bluuebunny/crossref_metadata_2025 huggingface dataset:
Od diagnozy do towarzyszenia w żałobie – wsparcie rodzin z dzieckiem z wadą letalną
Authors: JARZĘBIŃSKA ANETA
Published: January 2020

Aneta Jarzębińska, Od diagnozy do towarzyszenia w żałobie – wsparcie rodzin z dzieckiem z wadą letalną [From the diagnosis to the accompanying in mourning– support from the families of children with lethal defect]. Interdyscyplinarne Konteksty Pedagogiki Specjalnej, nr 22, Poznań 2018. Pp. 375-391. Adam Mickiewicz University Press. ISSN 2300-391X. DOI: https://doi.org/10.14746/ikps.2018.22.21

This article characterizes the interactions and institutions in which parents can receive support after their child has been diagnosed with a lethal defect. First and foremost parents need information and emotional support when making decision regarding their child. The primary source of the aforementioned elements is the hospital personnel and the perinatal hospice- that is if parents decide to contact it. If the child is born alive and discharged from the hospital then the parents require support during its treatment (which more often than not is identical with palliativecare) and rehabilitation, even social rehabilitation. Children’s hospices can offer many services in this particular matter. On each stage of the child’s disease the contact with other parents of children with lethal defect is crucial. They can negate the feeling of isolation, give practical advice regarding the situation and most of all give hope that even though the prognosis is fatal some of the children lived.
Recenzja monografii „Emocje dzieci i młodzieży z trudnościami w rozwoju i zachowaniu” (redakcja naukowa Barbara Winczura), wydawnictwo Oficyna Wydawnicza „Impuls”, Kraków 2017
Authors: KOWALIK STANISŁAW
Published: January 2020

.
Społeczne konstruowanie rytuałów i symboli akademickich
Authors: Grzesiak Emilia
Published: January 2020

Rites and ceremonies are very important in university reality. They are extremely important for maintaining the continuity of academic values and highlighting the rank of certain events, which is particularly visible during various academic ceremonies. This article will be devoted to academic rituals, ceremonies and symbols in the context of their social meaning and values. I refer this issue to other dimensions of socio-cultural reality (including ceremonial court practices), I will look for similarities, explaining their significance and roles. I will try to justify how – regarding their long history and tradition – we can understand them in the 21st century.
Od idei do realizacji – Ogrody dziecięce im. W.E. Raua w Warszawie 1899-1901
Authors: Wojewoda Anna
Published: January 2020

In the 19th and 20th centuries the idea of collective games in the open was very popular. The idea of developing physical activity of children was also accepted in the Kingdom of Poland. Drawing inspiration from Germany, Sweden, Belgium and France and inspired by Henryk Jordan Gardens in Krakow, representatives of the Warsaw Hygiene Society decided to set up similar gardens in Warsaw. After the enthusiastic opening of the garden in 1899, they quickly had to interrupt the fun to includ this type of activity in the Society. At that time, being unable to formally conduct collective games, members of the organizing committee were delegated abroad to seek inspiration and organizational and methodical solutions. W.E. Raue Children’s gardens re-started their activity in 1901, after obtaining the consent of the Ministry of the Interior.
A Krasnosel’skii-type theorem for certain orthogonal polytopes starshaped via k-staircase paths
Authors: Breen Marilyn
Published: January 2020

Let 𝒞 be a finite family of distinct axis-parallel boxes in ℝ
d
whose intersection graph is a tree, and let S = ⋃{C : C in 𝒞}. If every two points of S see a common point of S via k-staircase paths, then S is starshaped via k-staircase paths. Moreover, the k-staircase kernel of S will be convex via k-staircases.
A note on norms of signed sums of vectors
Authors: Chasapis Giorgos , Skarmogiannis Nikos
Published: January 2020

Improving a result of Hajela, we show for every function f with lim
n→∞
f(n) = ∞ and f(n) = o(n) that there exists n
0 = n
0(f) such that for every n ⩾ n
0 and any S ⊆ {–1, 1}
n
with cardinality |S| ⩽ 2
n/f(n) one can find orthonormal vectors x
1, …, xn
∈ ℝ
n
satisfying

∥

ε
1

x
1

+
⋯
+

ε
n

x
n

∥

∞

⩾
c

log
⁡
f
(
n
)

$\begin{array}{}
\displaystyle
\|\varepsilon_1x_1+\dots+\varepsilon_nx_n\|_{\infty }\geqslant c\sqrt{\log f(n)}
\end{array}$

for all (ε
1, …, εn
) ∈ S. We obtain analogous results in the case where x
1, …, xn
are independent random points uniformly distributed in the Euclidean unit ball

B
2
n

$\begin{array}{}
\displaystyle
B_2^n
\end{array}$

or in any symmetric convex body, and the

ℓ

∞

n

$\begin{array}{}
\displaystyle
\ell_{\infty }^n
\end{array}$

-norm is replaced by an arbitrary norm on ℝ
n
.
Topology of tropical moduli of weighted stable curves
Authors: Cerbu Alois , Marcus Steffen , Peilen Luke , Ranganathan Dhruv , Salmon Andrew
Published: January 2020

The moduli space Δ

g,w
of tropical w-weighted stable curves of volume 1 is naturally identified with the dual complex of the divisor of singular curves in Hassett’s spaces of w-weighted stable curves. If at least two of the weights are 1, we prove that Δ
0, w
is homotopic to a wedge sum of spheres, possibly of varying dimensions. Under additional natural hypotheses on the weight vector, we establish explicit formulas for the Betti numbers of the spaces. We exhibit infinite families of weights for which the space Δ
0,w
is disconnected and for which the fundamental group of Δ
0,w
has torsion. In the latter case, the universal cover is shown to have a natural modular interpretation. This places the weighted variant of the space in stark contrast to the heavy/light cases studied previously by Vogtmann and Cavalieri–Hampe–Markwig–Ranganathan. Finally, we prove a structural result relating the spaces of weighted stable curves in genus 0 and 1, and leverage this to extend several of our genus 0 results to the spaces Δ
1,w
.
Simulation of an Acid Gas Removal Unit Using a DGA and MDEA Blend Instead of a Single Amine
Authors: Zahid Umer
Published: January 2020

Most of the industrial acid gas removal (AGR) units employ chemical absorption process for the removal of acid gases from the natural gas. In this study, two gas processing plants operational in Saudi Arabia have been selected where two different amines n1amely, diglycolamine (DGA) and monoethanol amine (MDEA) are used to achieve the sweet gas purity with less than 4 ppm of H2S. This study performed a feasibility simulation of AGR unit by utilizing the amine blend (DGA+MDEA) for both plants instead of a single amine. The study used a commercial process simulator to analyze the impact of process variables such as amine circulation rate, amine strength, lean amine temperature, regenerator inlet temperature, and absorber and regenerator pressure on the process performance. The results reveal that when the MDEA (0–15 wt. %) is added to DGA, marginal energy savings can be achieved. However, significant operational energy savings can be made when the DGA (0–15 wt. %) is blended with MDEA being the main amine.
Dosage of phenytoin in neurocritical patients using Bayesian algorithms: a pilot study
Authors: Muñoz-Pichuante Daniel , Villa Zapata Lorenzo , Cabrera Salvador , Lagos Ximena , Grandjean Juan
Published: January 2020

Phenytoin is widely used in neurocritical patients. Owing to its high pharmacokinetic variability and narrow therapeutic range, plasma level-guided dosing has become the standard. Bayesian prediction (BP) is considered the most flexible and precise pharmacokinetic strategy among several options. A retrospective study of BP dosage adjustment in 20 patients (35 plasma measures) was developed. Results indicated that 70% of phenytoin plasma levels of first plasma samples were beyond the therapeutic range. Phenytoin doses were also estimated according to BP for all patients. The measurements confirmed the ability of the strategy to lead to optimal dosage in 80% of patients, thus indicating a three-fold improvement over the basing dosage adjustment recommended in the literature.
Design of a Miniaturized Class F Power Amplifier Using Capacitor Loaded Transmission Lines
Authors: Pirasteh Ali , Roshani Saeed , Roshani Sobhan
Published: January 2020

In this paper, a new method to decrease the dimensions of the microstrip structures and reducing the overall size of the class F amplifiers is presented. First, by using the PHEMT transistor with a conventional harmonic control circuit (HCC), a low-voltage class F amplifier in the L band frequency at the operating frequency of 1.75 GHz is introduced, which named primitive class F power amplifier. Then, this amplifier is optimized by using capacitor loaded transmission lines (CLTLs). The measurement results of the amplifier show that by using the CLTL structure, the overall size has been reduced 85% (0.23 λg × 0.17 λg). The maximum power-added efficiency (PAE) of the power amplifier is about 77.5 % and the power gain which has been reached to 18.33 dB. The desirable features of this power amplifier, along with its very small size, make this power amplifier a good choice to use for the global system for mobile communications.
Different counselors, many options: Career guidance and career plans in secondary schools
Authors: Fitzenberger Bernd , Hillerich-Sigg Annette , Sprietsma Maresa
Published: January 2020

Career guidance assists students with the school-to-work transition. Based on a survey conducted in secondary schools in Germany, we analyze career guidance activities and how these affect career plans. The take-up of career guidance depends upon the school track attended, and the school and the class setting, while personal characteristics are barely relevant. The effects of counseling depend upon the type of counseling provider. Counseling by the employment agency reduces plans for educational upgrading and increases the probability of applying for an apprenticeship, while the effects of counseling by school counselors works in the opposite direction for lower track students.
Determining predictors of change in sugar sweetened beverage consumption behaviour among university students in India
Authors: Sharma Ankur , Jain Meena , Nahar Vinayak K. , Sharma Manoj
Published: January 2020

Background

Consumption of sugar sweetened beverages (SSBs) is a significant risk behaviour that leads to the development of several chronic diseases. The present study aimed to predict the SSB consumption behaviour among Indian university students by utilising a multi theory model (MTM) of health behaviour change.

Methods

In a cross-sectional design, a validated 37-item self-report questionnaire was administered to 267 participants from a mid-size university in the National Capital Region (NCR) of India. Stepwise multiple regressions were used to determine predictors of change in initiation and sustenance of SSB consumption behaviour. For stepwise multiple regression, the a priori criteria of probability of F to enter the predictor in the model was set as less than or equal to 0.05 and for removing the predictor as greater than or equal to 0.10.

Results

The model was able to predict 16.7% variance in behavioural initiation through the constructs of participatory dialogue and behavioural confidence, and 30.2% variance in sustenance through emotional transformation and change in social environment. Participatory dialogue and behavioural confidence were predictors of behaviour initiation; and emotional transformation, and change in social environment were predictors of behaviour sustenance for SSB consumption behaviour change.

Conclusion

The study provided a pathway for design of interventions for SSB intake reduction in Indian university students. Interventions should be designed using participatory dialogue and behavioural confidence initiation, and emotional transformation and change in social environment for sustenance of change in SSB consumption in this population.
Antiaggregation effect of clopidogrel in coronary heart disease patients using omeprazole
Authors: Munthe Dian Hasiannami Boru , Sargo Siti Sjamsiah , Yogiarto Mohammad
Published: January 2020

Background

Antiplatelet agents used in coronary heart disease (CHD) cause gastrointestinal side effects. Omeprazole can prevent and cure these antiplatelet side effects. Clopidogrel combined with aspirin increases the risk of gastrointestinal tract ulcers and bleeding. This research studied the effect of omeprazole on the antiplatelet effect of clopidogrel.

Methods

CHD patients using clopidogrel and aspirin receive omeprazole 20 mg in a single dose for 10 days. Platelet antiaggregation point for clopidogrel was measured using VerifyNow P2Y12. The cutoff points used were: low on treatment platelet reactivity (LPR) <85 P2Y12 reaction unit (PRU), normal on treatment platelet reactivity (NPR) 85–208 PRU, and high on treatment platelet reactivity (HPR) >208 PRU.

Results

Using the paired t-test PRU points pre- and post-omeprazole were 154 ± 85.89 PRU and 169.4 ± 56.15 PRU, respectively. The PRU points were consistent or decreased from the previous PRU points below the HPR cutoff (p: 0.215; >0.05). Before omeprazole use, five patients were categorized as NPR, two patients as LPR, and three patients as HPR. After omeprazole use, two patients, each from HPR and NPR category had a PRU point >208; the rest showed results below the HPR point.

Conclusions

In this study the PRU points of clopidogrel after omeprazole use showed a PRU <208. The hypothesis that omeprazole may reduce the antiaggregation effect of clopidogrel as shown by the increase in PRU above the cutoff points >208 PRU (HPR) was not proven.
The enhancement of Arg1 and activated ERβ expression in microglia HMC3 by induction of 96% ethanol extract of Marsilea crenata Presl. leaves
Authors: Ma’arif Burhan , Agil Mangestuti , Laswati Hening
Published: January 2020

Background

Phytoestrogens have a high potential to overcome the neuroinflammation caused by estrogen deficiency. Marsilea crenata Presl. is a plant known to contain phytoestrogens. This research aimed to report the activity of a 96% ethanol extract of M. crenata leaves in inducing activation of microglia HMC3 cell to M2 polarity, which has anti-inflammatory characteristics.

Methods

The study was done by culturing microglia HMC3 cell in 24-well microplate and inducing it with IFN-γ for 24 h to activate the cell to M1 polarity, which has proinflammatory characteristics. The 96% ethanol extract was added with various doses of 62.5, 125, and 250 ppm. Genistein, 50 μM, was used as a positive control. The analysis of the immunofluorescence of Arginase-1 (Arg1) and ERβ as markers was done using a convocal laser scanning microscope.

Results

The result of Arg1 shows a significant difference in Arg1 expression in the microglia HMC3 cell line between the negative control and all treatment groups at p < 0.05, with the best result at 250 ppm, whereas for ERβ, the results show, at doses of 125 and 250 ppm, that the 96% ethanol extract of M. crenata leaves decrease the activated ERβ expression at p < 0.05, with the best result at 250 ppm. The Arg1 and activated ERβ expression have a weak negative relationship with the Pearson correlation test.

Conclusions

The 96% ethanol extract of M. crenata leaves has an antineuroinflammation activity through the induction of Arg1 and activated ERβ expression in microglia HMC3 cell, with the best dose at 250 ppm.
The relationship between the level of education and accuracy of insulin injection techniques in DM patients with measurement of HbA1c values
Authors: Achmad Anisyah , Sholihah Fatchur Rohmi Latifatus , Oktavianti Wanda Fenny , Sasiarini Laksmi
Published: January 2020

Background

Insulin therapy is a major part of diabetes treatment. The insulin injection technique must be done accurately and needs a professional process for diabetes mellitus (DM) patients. The aim of this research is to evaluate the relationship of education level pertaining to the accuracy of insulin injection techniques through HbA1c values.

Methods

We used a cross-sectional study with sampling using a purposive technique according to the inclusion criteria: diagnosed with DM and using insulin therapy with/without a combination of oral antidiabetic drugs, having HbA1c levels of data ± 3 months from the time of study, willing to become research respondents by signing informed consent. The study was conducted by filling out the questionnaire Forum for Injection Technique and Therapy Expert Recommendation (FITTER) and interviews.

Results

Fifty subjects with primary education were able to perform insulin injection techniques with 20% accuracy while subjects with secondary education level showed 14% accuracy, and higher education 2%. All of these results had HbA1c values > 6.5%. 100 % of the subjects were provided with educational resources and 78% had a care-giver at home. Statistical analysis of correlation between levels of education with the accuracy of the insulin injection technique was carried out through the Somers’ correlation test (p = 0.81, r = −0.03). This study shows there is no relationship between the level of education and the accuracy of insulin injection techniques through HbA1c values. This might occur due to several factors such as information sources and caregiver’s practice.
Crystal structure of triaqua-bis(2-(6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)-1-(2-oxo-2,5-dihydrofuran-3-yl)ethane-1-sulfonato-κ2
O,O′)calcium(II) – ethanol (1/2), C44H76CaO19S2
Authors: Ding Yuan-Min , Li Rui-Peng , Chang Ying-Jie , Zhao Jie , Liu Hong-Min , Li Wen
Published: January 2020

C44H76CaO19S2, monoclinic, C2 (no. 5), a = 25.5446(14) Å, b = 7.38025(19) Å, c = 18.8450(10) Å, β = 136.543(10)°, Z = 2, V = 2443.6(4) Å3, R
gt(F) = 0.0419, wR
ref(F
2) = 0.1161, T = 293(2) K.
Crystal structure of chlorido-(η
6-p-cymene)-(N-(2-fluorophenyl)-1-(pyridin-2-yl)methanimine-κ
2
N,N′)ruthenium(II) – acetone (1/1), C22H23ClN2F7OPRu
Authors: Gichumbi Joel M. , Omondi Bernard , Friedrich Holger B.
Published: January 2020

C22H23ClN2F7OPRu, monoclinic, P21/c (no. 14), a = 7.30480(10) Å, b = 12.9540(3) Å, c = 28.7076(6) Å, β = 96.6990(10)°, V = 2697.95(9) Å3, Z = 4, R
gt(F) = 0.0196, wR
ref(F
2) = 0.0479, T = 100(2) K.
The crystal structure of 2-bromoisonicotinic acid, C6H4BrNO2
Authors: Jia Hua-Li , Zhou Juan , Wang Xin , Zhao Hui , Feng Bo-Fang
Published: January 2020

C6H4BrNO2, monoclinic, P21/c (no. 14), a = 11.9715(14) Å, b = 7.5753(7) Å, c = 7.4498(8) Å, β = 102.302(4)°, V = 660.09(12) Å3, Z = 4, R
gt(F) = 0.0290, wR
ref(F
2) = 0.0635, T = 150(2) K.
Synergistic and antagonistic effects of soil applied P and Zn fertilizers on the performance, minerals and heavy metal composition of groundnut
Authors: Aboyeji Christopher Muyiwa , Dunsin Oluwagbenga , Adekiya Aruna Olasekan , Suleiman Khadijat Omowumi , Chinedum Chinomnso , Okunlola Faith Oluwatobi , Joseph Abiodun , Ejue Sunny Wutem , Adesola Oluwanifemi Omowumi , Olofintoye Temidayo A. Joseph , Owolabi Iyiola Oluwakemi
Published: January 2020

Nutrients use efficiency of plants could be affected by the antagonistic or synergistic effects of two or more elements in the soil leading to decreased or increased yield. Field experiments were conducted in 2017 and 2018 cropping seasons at the Landmark University Teaching and Research farm, Omu-Aran, Nigeria, to determine the interaction between zinc (Zn) and phosphate (P) fertilizers on growth, yield, nutrient elements and some heavy metals composition of groundnut grown on an Alfisol. Treatments consisted of four levels of phosphorus (0, 40, 80 and 120 kg P ha-1) and three levels of zinc (0, 4 and 8 kg Zn ha-1). The experiment was laid out in a Randomized Complete Block Design (RCBD), replicated four times. The following parameters were taken: plant height, plant spread, total biomass, number of pods/plot, weight of pods/plot, number of seeds/plot, weight of seeds/plot. Laboratory analysis of some chemical constituents of groundnut seed was carried out to determine the nutrient and heavy metals composition. Results indicated that application of 8 kg Zn ha-1 and 120 kg P ha-1 had a synergistic effect on the growth parameters and antagonistic effect on the yield, yield parameters, some nutrient elements and beneficial heavy metals. Application of 8 kg Zn and 80 kg P ha-1 is therefore recommended on an Alfisol without necessarily increasing the concentration of non-beneficial heavy metals in groundnut seed.
Down Presymptomatic View of Dementia Characteristics
Authors: Joshaghanian Mohammad Amin , Mohammadi Sassan , Gholizadeh Ghozloujeh Zohreh , Farahani Mehrdad , Mojtabavi Kurosh
Published: January 2020

Down syndrome (DS) is caused by complete or segmental chromosome 21 trisomy that results in neurodegeneration and progressive intellectual disability. Abnormal function in the prefrontal cortex, cerebellum, and hippocampus are the main reasons for cognitive deficits in DS that result in impaired cognitive function, delayed speech and language, learning and memory disability, and behavioral and emotional disorders. There is no specific treatment for DS, and our understanding of the mechanisms of the disorder is incomplete and causes to hamper the development of effective therapies regarding the development of neuropathology and memory loss in DS. Here, we review the literature on cognitive functioning, unique characteristics, environmental considerations, and recent findings on Alzheimer’s disease in DS.
Alterations in EGF-Endocytosis, Lysosomal Enzyme Transport and Maturation of Cathepsins in Juvenile Neuronal Ceroid Lipofuscinosis Fibroblasts
Authors: Cárcel-Trullols Jaime
Published: January 2020

Background: Juvenile neuronal ceroid lipofuscinosis (JNCL), one of the most frequent forms of the NCL storage diseases, is known to be caused by loss-of-function mutations in ceroid-lipofuscinosis neuronal protein 3 (CLN3), but its cell function has not been fully elucidated. We previously reported increased lysosomal pH in CLN3 deficient cells. In the present study, we analysed the consequences of this effect in the endo-lysosomal pathways in CLN3 cells. Methods: The present study investigated different endo-lysosomal pathways in control, CLN2, CLN3 human skin fibroblasts under high and low proteolysis conditions. Cell surface biotinylation after EGF (2 ng/mL) stimulation, EGF phosphorylation (Tyr-845), retromer and cation-independent mannose-6- phosphate receptor (CI-MPR) levels and stability, EGF degradation pathways and cathepsin L and D levels were analysed by western blots. Caveolae mediated endocytosis was analysed by flow cytometry. CIMPR subcellular localization was ascertained by immunocytochemistry, confocal microscopy and further image analysis. Results: Whereas caveolae-mediated endocytosis was not affected in CLN3 cells, clathrin-mediated epidermal growth factor (EGF) internalization was reduced, along with EGF receptor (EGFR) phosphorylation. In addition, cell surface EGFR levels and recycling to the cell membrane were increased. EGFR lysosomal degradation was impaired and our results suggest that the receptor was diverted to proteasomal degradation. We also analysed the machinery responsible for lysosomal hydrolase transport to the lysosome and found increased stability of CIMPR, a major receptor implicated in the transport of hydrolases. The subcellular distribution of the CI-MPR was also altered in CLN3 cells, since it accumulated within the Trans-Golgi network (TGN) and did not progress into the lysosomes. In addition, we found a reduced turnover of retromer subunits, a complex that retrieves the CI-MPR from endosomes to the TGN. Finally and as a possible consequence of these alterations in lysosomal enzyme transport, cathepsin L and D maturation were found suppressed in CLN3 cells. Conclusion: Altogether, these results point to increased lisosomal pH as a pivotal event causing various alterations in intracellular traffic associated to the development of JNCL disease.
Online Epileptic Seizure Prediction Using Phase Synchronization and Two Time Characteristics: SOP and SPH
Authors: Shokouh Alaei Hesam , Khalilzadeh Mohammad Ali , Gorji Ali
Published: January 2020

Background: The successful prediction of epileptic seizures will significantly improve the living conditions of patients with refractory epilepsy. A proper warning impending seizure system should be resulted not only in high accuracy and low false-positive alarms but also in suitable prediction time. Methods: In this research, the mean phase coherence index used as a reliable indicator for identifying the preictal period of the 14-patient Freiburg EEG dataset. In order to predict the seizures on-line, an adaptive Neuro-fuzzy model named ENFM (evolving neuro-fuzzy model) was used to classify the extracted features. The ENFM trained by a new class labeling method based on the temporal properties of a prediction characterized by two time intervals, seizure prediction horizon (SPH), and seizure occurrence period (SOP), which subsequently applied in the evaluation method. It is evident that an increase in the duration of the SPH can be more useful for the subject in preventing the irreparable consequences of the seizure, and provides adequate time to deal with the seizure. Also, a reduction in duration of the SOP can reduce the patient’s stress in the SOP interval. In this study, the optimal SOP and SPH obtained for each patient using Mamdani fuzzy inference system considering sensitivity, false-positive rate (FPR), and the two mentioned points, which generally ignored in most studies. Results: The results showed that last seizure, as well as 14-hour interictal period of each patient, were predicted on-line without false negative alarms: the average yielding of sensitivity by 100%, the average FPR by 0.13 per hour and the average prediction time by 30 minutes. Conclusion: Based on the obtained results, such a data-labeling method for ENFM showed promising seizure prediction for online machine learning using epileptic seizure data. Apart from that, the proposed fuzzy system can consider as an evaluation method for comparing the results of studies.
Integration of Wavelet and Recurrence Quantification Analysis in Emotion Recognition of Bilinguals
Authors: Goshvarpour Ateke , Goshvarpour Atefeh , Abbasi Ataollah
Published: January 2020

Background: This study offers a robust framework for the classification of autonomic signals into five affective states during the picture viewing. To this end, the following emotion categories studied: five classes of the arousal-valence plane (5C), three classes of arousal (3A), and three categories of valence (3V). For the first time, the linguality information also incorporated into the recognition procedure. Precisely, the main objective of this paper was to present a fundamental approach for evaluating and classifying the emotions of monolingual and bilingual college students. Methods: Utilizing the nonlinear dynamics, the recurrence quantification measures of the wavelet coefficients extracted. To optimize the feature space, different feature selection approaches, including generalized discriminant analysis (GDA), principal component analysis (PCA), kernel PCA, and linear discriminant analysis (LDA), were examined. Finally, considering linguality information, the classification was performed using a probabilistic neural network (PNN). Results: Using LDA and the PNN, the highest recognition rates of 95.51%, 95.7%, and 95.98% were attained for the 5C, 3A, and 3V, respectively. Considering the linguality information, a further improvement of the classification rates accomplished. Conclusion: The proposed methodology can provide a valuable tool for discriminating affective states in practical applications within the area of human-computer interfaces.
The preventive effect of Nigella sativa seed on gastric ulcer induced by indomethacin in rat
Authors: Paseban Maryam , Niazmand Saeed , Soukhtanloo Mohammad , Tayyebi Meybodi Naser
Published: January 2020

Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are considered as one of the most administrated groups of medications worldwide. Due to the role of NSAIDs in inducing gastric ulceration, their clinical applications are still challenging. Nigella sativa seed is widely used as an herbal medication against gastrointestinal complications. The present experiment was carried out to investigate the impact of N. sativa seed hydro-alcoholic extract on gastric ulcer induced by indomethacin (IND) and to evaluate its possible mechanisms in rat. Methods: This study was performed on 48 male Wistar rats. Acute gastric ulceration was induced by IND (35 mg/kg). N. sativa seed extract (100, 200, 400 mg/kg) and ranitidine (50 mg/kg) were administered orally for five days before the induction ulcer. Ulcer index, gastric acid secretion, gastric mucus content, glutathione (GSH), malondialdehyde (MDA), total hexose, gastric juice protein content were determined on the fifth day. Results: The ulcer index in all groups of N. sativa seed was significantly lower than that of the IND group. N sativa seed considerably decreased MDA and protein content, but increased total thiol, total hexose, and mucus content compared to the IND group. N. sativa seed did not affect gastric acid secretion. Conclusion: These findings were indicative of the gastroprotective effect of N. sativa seed against the IND-induced ulcer, suggesting that it can mainly be exerted through the anti-oxidant activity of the extract as well as its role in stimulating gastric mucus secretion and increasing total hexose in the gastric mucosa.
Antitumor activity of methoxylated flavonoids separated from Achillea fragrantissima extract in Ehrlich’s ascites carcinoma model in mice
Authors: Awad Basma M. , Abd-Alhaseeb Mohammad M. , Habib Eman S. , Ibrahim Amany K. , Ahmed Safwat A.
Published: January 2020

Introduction: Achillea fragrantissima extract has been used in folk medicine as an anticancer. The present study describes the antitumor activities of the extract and the flavonoid compounds and attempts to explain the mechanisms underlying these activities. Methods: The whole plant of A. fragrantissima was collected and ground to produce a fine powder which subjected to the maceration process. Step gradient elution was used using silica gel vacuum liquid chromatography (VLC). The fractions were compared by thin layer chromatography (TLC) and concentrated. Final purification was performed using Sephadex LH-20 to give three compounds cirsiliol, chrysosplenol D and cirsimaritin from F4 and one compound, eupatilin-7-methyl ether from F6. In this study, Ehrlich’s ascites carcinoma (EAC) model was used as the model of cancer. Results: Achillea fragrantissima extract and its isolated methoxylated flavonoids significantly reduced the weight of tumor discs compared to EAC-control group. In addition, cirsimaritin and eupatilin 7-methyl ether treatments produced a dose-dependent reduction in tumor weight. Serum tumor necrosis factor-alpha (TNF-ɑ) level showed that A. fragrantissima extract and its isolated methoxylated flavonoid compounds significantly reduced its serum level compared to the EAC-control group. Furthermore, A. fragrantissima extract and the flavonoids significantly increased the Total antioxidant capacity (TAC) compared to EAC-control. A. fragrantissima extract and its isolated methoxylated flavonoids produced a better differentiation of tumor cells, with reduced nuclear pleomorphism and better formed tubular structures especially with high dose indicating the induction of apoptotic mechanism. Conclusion: Achillea fragrantissima extract and its isolated methoxylated flavonoids exhibit antitumor activities that may be attributed to the antioxidant properties and the induction of the apoptotic process.
Feverfew attenuates carbon tetrachloride-induced testicular damage in rats
Authors: Mazani Mohammad , Banaei Shokofeh , Rezagholizadeh Lotfollah
Published: January 2020

Introduction: Feverfew is an herbal medicine with the traditional usage of treating several disorders. Some investigations have demonstrated that feverfew is an effective remedy for the prophylactic treatment of inflammatory conditions, migraine and menstrual disorders. Therefore, this study was arranged out to evaluate the protective or curative potentials of feverfew methanolic extract (FME) on carbon tetrachloride (CCl4) induced oxidative trauma in testis. Methods: In this experiment, male Wistar rats were divided into seven groups (n=6). Group I as a normal control received 1 mL/kg distilled water for 14 days orally and on the 14th-day olive oil (1.5 mL/kg, i.p.). Group II received 1 mL/kg distilled water orally for 14 consecutive days. Groups III, IV and V animals were pretreatment groups and treated with three different doses of FME (40, 80, and 120 mg/kg, p.o, respectively) for 14 days. All groups except group one, were also intoxicated with 1.5 ml CCl4 (i.p, in a 1:1 dilution with olive oil) on the 14th day. Groups VI and VII were post-treatment groups and received FME (80 and 120 mg/kg, p.o, respectively) at 2, 6, 24 and 48 h after CCl4 injection. Results: Injection of CCl4 significantly (P < 0.001) reduced antioxidant enzymes (SOD and GPx) and increased malondialdehyde when compared to the control group. Administration of FME significantly (P < 0.05) improved these alterations near to control rats. Conclusion: It is suggested that FME has the ability to protect testis against oxidative damage, possibly through antioxidant effects of its bioactive compounds.
Effects of cinnamon extract on complications of treatment and eradication of Helicobacter pylori in infected people
Authors: Imani Ghazal , khalilian Alireza , Dastan Dara , Imani Behzad , Mehrpoya Maryam
Published: January 2020

Introduction: Treatment of Helicobacter pylori has various side effects like antibiotic resistance. The purpose of this study was to evaluate the effects of cinnamon extract on complications of treatment and eradication of H. pylori in infected people. Methods: In this randomized clinical trial, a total of 98 eligible healthy and H. pylori-infected patients approved by esophageal endoscopy were selected. The cinnamon group received multi-drug treatment including clarithromycin, amoxicillin and pantoprazole as well as a cinnamon extract capsule. The control group received multi-drug treatment and a 40 mg starch capsule. In order to analyze the cinnamon extract efficacy, the urea breath test (UBT) was performed 3 months after the start of treatment. Clinical symptoms were evaluated by a questionnaire at the beginning (day of 0), 7 days and 14 days after starting treatment. Results: The clinical symptoms such as nausea, vomiting, diarrhea, constipation, blurred vision, headache, metallic flavor, epigastric pain, burp, and appetite were significantly reduced in the cinnamon group (P < 0.05). The odds ratio exhibited a higher eradication rate of H. pylori in the cinnamon group (73.47% in the cinnamon group compared to 53.06% in the control group) (P = 0.036). Conclusion: Cinnamon as assisted therapy is able to alleviate the disease and reduce the complications of H. pylori treatment.
Effects of gallic acid on rat testopathy following morphine administration: an experimental study
Authors: Jalili Cyrus , Abdolmaleki Amir , Roshankhah Shiva , Salahshoor Mohammad Reza
Published: January 2020

Introduction: Morphine (MOR) as a psychoactive agent in the opium family causes free radicals accumulation which leads to failure in spermatogenesis. Gallic acid (GA), a polyphenolic acid, is found in various plants with antioxidant, anti-fungal, anti-viral, and anti-allergic activities. The purpose of this study was to evaluate the effects of GA against MOR-induced damage to the reproductive parameter of rats. Methods: Sixty-four male Wistar rats (8 weeks, 220-250 g) were categorized into 8 groups by random (n=8/each); normal control and MOR control groups; GA groups (5, 10, 20 mg/kg) and MOR + GA groups (5, 10, 20 mg/kg). Treatments were administered intraperitoneally (i.p), daily for 4 weeks. The sperm parameters, spermatogenesis index (SI), total antioxidant capacity, testosterone level, and seminiferous tube diameter (STD) were assessed. Results: All sperm parameters reduced significantly in the MOR control group than to the normal control group (P < 0.01). All parameters were significantly improved in GA and GA + MOR treatment groups compared to the MOR control group (P < 0.01). Conclusion: MOR caused a detrimental effect on male reproductive parameters. Also, no significant modifications were observed in all doses of GA treatments in comparison with the normal control group. GA compensates the toxic effect of MOR on reproductive parameters. Hence, GA administration is beneficial in MOR users.
Phytochemical analysis and anti-inflammatory activity of Cladophora aegagropila extract
Authors: Aleksandrova Aleksandra , Nesterkina Mariia , Gvozdii Svitlana , Kravchenko Iryna
Published: January 2020

Introduction: The aim of this research is centered on phytochemical analysis and anti-inflammatory activity of Cladophora aegagropila extract. Methods: Total flavonoid content in the appropriate ethanol extract of C. aegagropila was determined using the spectrometric method. Anti-inflammatory activity was evaluated by the models of carrageenan-induced and allyl isothiocyanate-induced (AITC-induced) inflammation of hind limb in rats. Experimental animals were divided into 3 groups, 5 animals each: 1st group – control; the animals without therapy of induced inflammation, 2nd group – animals were treated with application of 5% ointment containing C. aegagropila; 3rd group – animals were treated with application of 5% ibuprofen. Evaluation of anti-inflammatory activity was performed by determination of dynamic change of thickness and volume of affected animal limb for carrageenan-induced inflammation for 8 days (with daily registration of records), and for AITC induced inflammation for 24 h (with registration of records after 30 min, 1 h, 2 h, 3 h, 6 h and 24 h since phlogogen was introduced). Results: Flavonoids content in C. aegagropila extract varied depending on ethanol concentration: usage of 40% ethanol led to 18.2 mg of flavonoid recovery on 1.0 g of dry raw material; 70% ethanol – 39.5 mg and 96% ethanol – 35.5 mg. Therapy of 5% ointment based on C. aegagropila extract decreased inflammatory response caused by the subplantar introduction of the corresponding phlogogen. Conclusion: The ointment from C. aegagropila extract shows anti-inflammatory activity by inhibiting inflammation caused by AITC and carrageenan.
Reparar o Erro Através do Casamento: Honra, Moral e Sexualidade em um Trâmite Judicial
Authors: Silva Alécio Gonçalves da
Published: January 2020

Em suma, a história dessa narrativa busca lançar um olhar historiográfico sobre figuras e acontecimentos. Elegemos para tanto, enquanto fonte histórica principal um caso judicial, este em específico ocorrido na década de 80 do século XX, mas precisamente em 1982. Tratando-se de uma ação judicial cível de “Suprimento de Idade para Casamento”. O desenrolar do fato gravado nas páginas dos autos, torna necessário, por si só, uma reflexão acerca dos fios e teias que urdiram a partir das relações de micropoderes um sistema estrutural maior, mais complexo, aqui entendido enquanto a sociedade disciplinar e de controle. A partir deste caso e com outras fontes disponíveis, buscamos refletir sobre as redes invisíveis de interesses, inscritas substancialmente nos procedimentos técnicos, dentro dos discursos de saber-poder médico e jurídico embebidos pela lógica social disciplinar.Palavras-chave: Ação Judicial; Suprimento de Idade para Casamento; Sexualidade; Sociedade Disciplinar e de Controle. AbstractIn short, the history of this narrative seeks to cast a historiographical look at figures and events. To this end, we have chosen, as the main historical source, a judicial case, specifically in the 80's of the twentieth century, but precisely in 1982. This is a civil lawsuit of “Marriage Age Supply”. The unfolding of the fact recorded in the pages of the file, in itself, requires a reflection on the threads and webs that wove from the relations of micropowers a larger, more complex structural system, understood here as the disciplinary and control society. From this case and with other available sources, we seek to reflect on the invisible networks of interests, inscribed substantially in technical procedures, within the discourses of medical and legal know-how embedded in the disciplinary social logic.Keywords: Lawsuit; Age Supply for Marriage; Sexuality; Disciplinary and Control Society.
Wilde, Zola, Dreyfus, Christ
Authors: Counter Andrew J.
Published: January 2020

Oscar Wilde and Émile Zola are conventionally opposed as the figureheads of, respectively, the aestheticist and the naturalist literary trends. Yet they exhibit a number of uncanny similarities—not least the turn both made in their last years toward religious themes and imagery, and especially those of martyrdom and the Passion. This article explores such images in the later life, work, and public persona of each writer and sets them within the context of the dizzying proliferation of references to Christ and martyrdom in fin de siècle culture. It examines the “entailments”—the unexpected consequences, meanings, and echoes—that these overdetermined themes brought in their train from the wider literary field and shows how those entailments were exacerbated by the massive politicization of “martyr” discourse around the time of the Dreyfus affair, when the theme acquired its fullest significance.
Promotion of Hyperthermic-Induced rDNA Hypercondensation in Saccharomyces cerevisiae
Authors: Shen Donglai , Skibbens Robert V
Published: January 2020

Ribosome biogenesis is tightly regulated through stress-sensing pathways that impact genome stability, aging and senescence. In Saccharomyces cerevisiae, ribosomal RNAs are transcribed from rDNA located on the right arm of chromosome XII. Numerous studies reveal that rDNA decondenses into a puff-like structure during interphase, and condenses into a tight loop-like structure during mitosis. Intriguingly, a novel and additional mechanism of increased mitotic rDNA compaction (termed hypercondensation) was recently discovered that occurs in response to temperature stress (hyperthermic-induced) and is rapidly reversible. Here, we report that neither changes in condensin binding or release of DNA during mitosis, nor mutation of factors that regulate cohesin binding and release, appear to play a critical role in hyperthermic-induced rDNA hypercondensation. A candidate genetic approach revealed that deletion of either HSP82 or HSC82 (Hsp90 encoding heat shock paralogs) result in significantly reduced hyperthermic-induced rDNA hypercondensation. Intriguingly, Hsp inhibitors do not impact rDNA hypercondensation. In combination, these findings suggest that Hsp90 either stabilizes client proteins, which are sensitive to very transient thermic challenges, or directly promotes rDNA hypercondensation during preanaphase. Our findings further reveal that the high mobility group protein Hmo1 is a negative regulator of mitotic rDNA condensation, distinct from its role in promoting premature condensation of rDNA during interphase upon nutrient starvation.
Ungleichheit und Ungerechtigkeit
Authors: Hufe Paul , Peichl Andreas , Stöckli Marc
Published: January 2020

Einkommensungleichheit ist ein in der Öffentlichkeit heiß diskutiertes Thema. Die gängigen Ungleichheitsmaße sind jedoch wenig informativ, um Aussagen über die Fairness einer gegebenen Einkommensverteilung zu treffen. In diesem Artikel betrachten wir drei verschiedene Fairness-Prinzipien und zeigen, dass normative Bewertungen von Einkommensverteilungen stark von dem jeweilig betrachteten Prinzip abhängen. Um diese Uneindeutigkeit zu umgehen, diskutieren wir zudem eine neue Messmethode, die alle drei Prinzipien in einem zusammenfassenden Maß unfairer Ungleichheit kombiniert.
Application of learning scenarios quality evaluation methods
Authors: Kurilovas Eugenijus , Žilinskienė Inga
Published: January 2020

The paper is aimed to analyse the problems of evaluation of quality of learning scenarios. Multiple criteria analysis principles are applied to form learning scenarios quality model. Several alternativesof learning scenarios that are widely used in Europe are analysed in the paper. These alternatives are evaluated with the help of the created quality model and application of triangular and trapezoidalfuzzy numbers methods. Research results show that both these methods are applicable in practice while evaluating quality of learning scenarios alternatives, and their application shows in principlesimilar results while comparing different alternatives of learning scenarios.
A specialization of definitions in common knowledge logic
Authors: Girčys Aurimas Paulius , Pliuškevičius Regimantas
Published: January 2020

It is known that one of main aims of specializations of derivations in nonclassical logics is the various tools which allow us to simplify the searching of termination of derivations. The traditional techniques used to ensure termination of derivations in various non-classical logics are based on loop-checking. In this paper the reflexive common knowledge logic based on modal logic K2 is considered. For considered logic a sequent calculus with specialized non-logical (loop-type) axioms is presented.
Schedules of lectures and Monte Carlo method
Authors: Grigorjev Nikolaj , Stepanauskas Gediminas
Published: January 2020

In this paper the problem of the construction of schedule of lectures is considered. The Markov chain Monte Carlo method is used. A particular program based on simulated annealing algorithm was created.
Semantics Analysis on the Relation of Meaning of Cultural Differences toward the Translation from Bahasa Indonesia to English
Authors: Pudjianti Danti
Published: January 2020

This article aims to explain how to translate the words of Bahasa Indonesia with the local cultural meaning, as sources language, to English, as target language. the mentioned words are taken from short story and would translate in the level og textual and referential level. firstly, it tried to find the meaning of the words based on the bilingual dictionary, Indonesian-English. Furthermore, they are consulted to the monolingual dictionary. finally the translation used is those accepted in target language speaking through the translation techniques, namely contextual conditioning.
Spektrum: Kebesaran Gayo dalam Pentas Seajarah
Authors: Madjid M. Dien
Published: January 2020

Dalam file scan
Al Muhassinat al Lafdziyyah al-Ma'nawiyah
Authors: Raswan Raswan
Published: January 2020

Study of badi has passed through various phases of the term. Badi 'grow and develop into a big lead and then retreating to his study and pragmatic. The first person credited codify badi 'is Ibn Mu'taz, then badi' is analyzed theby the exciting and challenging to Abdu al-an-Nabulisi Ghaniy formulated more than 160 scientific studied on badi'. Subsequent devlopment of science badi' orientation to orientation decreased pragmatic, not unlike just memorizing rules and unable to come to tadzawwuq balaghi.Study of badi'increasingly leaving only a few studies have considered the main pragmatic language in the Koran dive like the one in the book such as al-al-Wadhihah Balaghah, Jawahir al-Balagha, Jauhar al-Maknun etc.. Balaghah studies are still in existence and is considered the primary will be presented in this article.