bluuebunny/crossref_metadata_2025 huggingface dataset:
Irreversible HIV-1 Inactivation Employing a Small Molecule Dual-Action Virolytic Entry Inhibitor Strategy
Authors: Gaffney Althea , Nangarlia Aakansha , Gossert Steven , Rashad Adel A. , Hossain Alamgir , Abrams Cameron , B. Smith III Amos , Chaiken Irwin M.
Published: July 2019

The design, synthesis and validation of a family of small molecule “Dual-Action Virucidal EntryInhibitors” (DAVEIs) has been achieved that result in irreversible lytic inactivation of HIV-1 virions. These constructs contained two functional components that endow the capacity to bindsimultaneously to both the gp120 and gp41 subunits of the HIV-1 Envelope glycoprotein (Env). One component is derived from BNM-III-170, a small molecule CD4 mimic warhead that binds togp120. The second component, a Trp3 peptide, is a 9-amino acid segment based on the gp41 Membrane Proximal External Region (MPER) that has been proposed to bind to the gp41 MPERdomain of the Env. The resulting smDAVEIs both inhibit infection with low micromolar potency and induce lysis of the HIV-1 virion. The lytic activity was selective for functional HIV-1 virions. Crucially, virolysis was found to be dependent on covalent tethering of the BNM-III-170 and Trp3 domains with various spacers, as coadministration of the un-crosslinked components proved not to be lytic. Computational modeling supports a mechanism in which DAVEIs bind to open-state Env trimers and induce relative motion of gp120 subunits that further opens the trimers. Overall, this work represents a promising new step toward the use of small-molecule DAVEIs for eradication of HIV.
Modeling Interfacial Electron Transfer in the Double Layer: The Interplay Between Electrode Coupling and Electrostatic Driving
Authors: Limaye Aditya , Willard Adam
Published: July 2019

This manuscript presents a theoretical model for simulating interfacial electron transfer reactions within the electrical double layer. This model resolves the population density of redox active species and simulated electron transfer at the level of Marcus theory, with a fluctuating solvent polarization coordinate. In this model, the kinetics and thermodynamics of electron transfer depend on the values of the electronic coupling of species (to the electrode) and the electrical potential drop, respectively.
Targeted Covalent Inhibition of Telomerase
Authors: Betori Rick , Liu Yue , Wu Ding , Mishra Rama , Cohen Scott , Kron Stephen J. , Scheidt Karl
Published: July 2019

Telomerase is a ribonuceloprotein complex responsible for maintaining telomeres and protecting chromosomal integrity. The human telomerase reverse transcriptase (hTERT) is expressed in ~90% of cancer cells where it confers the capacity for limitless proliferation. Along with its established role in telomere lengthening, telomerase also serves non-canonical extra-telomeric roles in oncogenic signaling, resistance to apoptosis, and enhanced DNA damage response. Here, we report a new class of natural product-inspired covalent inhibitors of telomerase that target the catalytic active site. We developed rationally designed probe compounds that modulate both the telomeric and extra-telomeric activities of telomerase and present new opportunities to investigate the diverse functions of this unique molecular machine.
Demystifying the Soai Reaction
Authors: Athavale Soumitra , Simon Adam , Houk Kendall N. , Denmark Scott
Published: July 2019

The extraordinary Soai reaction has profoundly impacted chemists’ perspective of chiral symmetry breaking, absolute asymmetric synthesis and its role in the origin of biological homochirality. Herein, we describe the unprecedented observation of asymmetry amplifying autocatalysis in the alkylation of 5-(trimethylsilylethynyl)pyridine-3-carbaldehyde using diisopropylzinc. Kinetic studies with a “Trojan-horse” substrate and spectroscopic analysis of a series of zinc-alkoxides that incorporate specific structural mutations reveal a ‘pyridine-assisted cube escape’. The new cluster functions as a catalyst that activates the ‘floor-to-floor’ bound aldehyde and poises a coordinated diisopropylzinc moiety for alkyl group transfer. Transitionstate models leading to both the homochiral and heterochiral products were validated by density functional theory calculations. Moreover, experimental and computational analysis of the heterochiral complex provides a definitive explanation for the non-linear behavior of this system. Our deconstruction of the Soai system contributes substantially to understanding the mechanism of this transformation that has stood as a longstanding challenge in chemistry.
El Eternauta:
Authors: Gago Sebastian Horacio
Published: July 2019

Este artigo se propõe a estudar a recepção da obra do quadrinhista Héctor Germán Oesterheld. O seu título El Eternauta, é considerado hoje em dia um clássico da literatura argentina.  Construímos uma abordagem teórica e metodológica qualitativa do consumo de quadrinhos, que nos permite estudar a leitura em relação a uma série de condições de produção de sentido: a trajetória de consagração da obra e do autor, o momento histórico do consumo, e as biografias leitoras dos indivíduos. Nossa principal conclusão indica que a mudança parcial de posição de Oesterheld dentro do campo dos quadrinhos da Argentina – de roteirista da indústria editorial, passou a ser valorado como um intelectual desaparecido –, deixa sua marca nas leituras atuais da sua obra em direção a uma maior carga de níveis políticos de interpretação.
É para rir ou para chorar?
Authors: Crescêncio Cintia Lima
Published: July 2019

O objetivo deste texto é refletir sobre a emergência de uma modalidade de humor e, consequentemente, de riso, que tomou forma na imprensa alternativa feminista brasileira em tempos de ditadura: o humor gráfico. A partir do levantamento de uma série de charges/tirinhas com viés feminista defendo a ideia de que, a partir do humor e do riso, a imprensa feminista do Brasil desenvolveu uma modalidade de crítica social e cultural que se caracteriza por uma linguagem que desestabiliza o binômio sério/cômico, criando o que chamo de riso feminista.
Ciência e tecnologia nos mundos imaginários de Yantok:
Authors: Queluz Marilda Lopes Pinheiro
Published: July 2019

O objetivo deste texto é refletir sobre as Aventuras de Kaximbown, de Max Yantok, publicadas na revista O Tico-Tico, entre 1911 e 1913. Nessas narrativas de nonsense e aventura, os personagens partem em viagens interplanetárias, descobrindo mundos imaginários, com seres fantásticos e outras formas de organização social, em espaços povoados de engenhosidades, máquinas mirabolantes e artefatos bizarros. O humor é construído pelos contrastes, pelo estranhamento e por uma crítica sutil às soluções técnico-científicas e às reformas urbanas. Yantok cria, graficamente, não lugares, entrelaçando elementos utópicos e distópicos, em uma paródia da modernização brasileira na Primeira República.
Resistência escrava em um contexto de pequenas posses:
Authors: Malaquias Carlos De Oliveira , Costa Ana Carolina De Rezende
Published: July 2019

O artigo aborda a questão das fugas de escravos na perspectiva dos senhores que publicaram anúncios no periódico mineiro Astro de Minas entre 1827-1839. Busca-se conhecer quem eram os senhores que enfrentaram a fuga de seus escravos e quais as características de suas posses. Além dos anúncios de fuga, lança-se mão de um conjunto variado de documentos, como listas e mapas de moradores, inventários e processos-crime. Percebe-se que todos os senhores estavam sujeitos à fuga, mesmo os donos de pequenas escravarias, fato que sugere que a evasão do cativeiro relacionava-se a tensões no exercício senhorial de mando, mais do que com condições materiais previamente postas.
Feitiços, batuques e Códigos de Posturas:
Authors: Vieira Fábio Amorim , Debortoli Gabrielli
Published: July 2019

O presente artigo busca compreender as ações de controle policial diante das práticas de fé e religiosidade das populações de origem africana na ilha de Santa Catarina durante a segunda metade do século XIX. Para tal intento, serão analisadas fontes como os Códigos de Posturas do período, edificados pelos setores dominantes de modo a disciplinar a circulação e os atos dessas populações no espaço urbano desterrense. Também se incluirão à análise deste trabalho outros vestígios documentais, tais como processos criminais e autos policiais, em que esses sujeitos de origem africana, bem como alguns indícios de práticas e crenças suas, estejam presentes em relação aos modelos de postura e anseios projetados a essas pelas legislações e suspeições policiais, sugerindo reflexos de suas ações e protagonismos no contexto.
AN APPROACH TO JOHN WITTE ON THE REFORMATION OF RIGHTS AND RELIGION
Authors: KOKOBILI Alexander
Published: July 2019

This article focuses on the insight of Professor John Witte Jr., (b. 1959) in relation to human rights and religion. Witte has a distinctive theological path with vast scholarly works in connection to ethics, law and human rights at the Emory University in Atlanta. Although the origin of human rights has been interpreted differently by many authors in the past. However, Witte's exposure to the emergence of modern human rights gives attention to its religious roots and the establishment of the 1948 Universal Declaration of Human Rights. The concept of religious freedom and individual rights was paramount in Calvinism, while the Papacy also tried in the reformation of its Canon Law. The 1948 United Nations Human Rights Charter came at a time when the project of human rights became inevitable after the mass atrocities caused by World War II. This article will, therefore, give a unique understanding of the emergence of modern human rights through a religious dialogue.
Barreras para el acceso a la planificación familiar, comunidad indígena Mandu’arã. Caaguazú, Paraguay 2017
Authors: Díaz Pedro
Published: July 2019

La planificación familiar es una forma de pensar y vivir, adoptada voluntariamente por individuos y parejas, basada en conocimientos y actitudes de cara a promover la salud y el bienestar de la familia y de la comunidad. Este concepto hace alusión al derecho de las personas a regular su fertilidad; que, pensado desde esa óptica, se convierte fundamentalmente en un derecho sexual, pero que, a la vez, influye en el cumplimiento de los derechos reproductivos. Es un hecho que las condiciones de marginación, exclusión y pobreza, que enfrentan los pueblos indígenas obstaculizan el ejercicio de sus derechos sexuales y reproductivos. Sin embargo, existen factores culturales que incrementan esta problemática como son: los roles tradicionales de género y el no reconocimiento de los derechos de las mujeres a decidir sobre su cuerpo, su sexualidad y el número de hijos que desean tener. En Paraguay existen 112.848 habitantes aborígenes, 54.473 de ellos son mujeres, según el III Censo Nacional de Población y Vivienda para Pueblos Indígenas 2012.
Unidad modular para obtención de extracto líquido de stevia para microproductores de Itapúa, Paraguay
Authors: Arza Patiño César Emilio , Cardozo Vargas Carlos Alberto
Published: July 2019

En Itapúa existe potencial para el cultivo de Stevia, de la variedad Eirete. Se podría obtener un extracto líquido mediante proceso de infusión a 80ºC durante 60 minutos, en una concentración 1:20 [g:ml]. Se diseñó una unidad modular como alternativa económica y práctica para microproductores dedicados a la agricultura familiar. Ésta constaría de un tanque de acero inoxidable de 400 litros, un agitador de paletas y un calentador por resistencia eléctrica, además de los sistemas auxiliares. Macro, micro, ultra y nanofiltración permitirían obtener el extracto. Se consideraron los requerimientos para productos alimenticios en la selección de los materiales y para el diseño se tomó como base un cultivo de una hectárea, con una producción anual de 5.000 kg de hojas secas, procesadas en lotes de 17 kg/día. Basados en investigaciones afines se tendría un total teórico de 13 kg de extracto en concentración de 10% de glucósidos y un aprovechamiento de 163 kg de rechazo de la filtración, como abono y fertilizante natural. Se considera factible la idea de diseñar una unidad productiva orientada al productor minifundiario, a fin de reactivar el rubro de la Stevia (Ka’a Heé) y dotarle de un valor agregado.
Avances que produce la estimulación oportuna en el aprendizaje de una lengua extranjera en niños de 5 años de la Ciudad De Asunción
Authors: Quiñonez Silguero Gloria María Elizabeth
Published: July 2019

La investigación se originó ante la pregunta ¿Qué avances produce la estimulación oportuna en el aprendizaje de la lengua extranjera en niños de 5 años del grupo A de un colegio de gestión estatal de Asunción en el año 2018? Debido a la necesidad de nuevas estrategias para efectivizar el proceso de enseñanza – aprendizaje de un idioma extranjero.
Paraguay: una reseña de su participación y desafíos futuros en el sistema multilateral de comercio. Periodo 1995 – 2016
Authors: Cabral López María Antonella
Published: July 2019

El comercio es una actividad de larga data, que puede decirse fue realizada intensamente desde la antigüedad. A través de la misma, oferentes y demandantes de distintos puntos podían intercambiar bienes. En particular, durante el siglo XX se registraron una serie de avances notables en materia de comercio internacional, los que fueron posibles gracias a la evolución de la tecnología, la infraestructura y ciertas cuestiones institucionales, como ser la constitución de organismos internacionales y el establecimiento de mecanismos para que este proceso sea facilitado.
El pensamiento crítico en la formación profesional: indicadores para el desarrollo de las habilidades cognitivas del pensamiento crítico en la Facultad de Filosofía de la Universidad Nacional de Asunción
Authors: Canese de Estigarribia Marta Isabel , Chávez Selva , Cáceres Mercado Sergio , Estigarribia Velázquez Ricardo , Ibarra Gustavo , Bogado Francisco , Lugo Christian , Valenzuela Rocío
Published: July 2019

Este informe de investigación presenta los resultados parciales del proyecto de investigación que tiene por objetivo la elaboración de una guía de indicadores para el desarrollo de las habilidades cognitivas del pensamiento crítico en la Facultad de Filosofía de la UNA.
Educación participativa y la investigación en las Ciencias Exactas y Naturales
Authors: Yubero Fátima
Published: July 2019

La ciencia es un bien público, el cual debe ser preservado porque es una fuente de variedad. Uno de los aspectos relevantes en ciencias es su difusión. En la Primera Encuesta Nacional sobre Ciencia y Tecnología, grupos focales encuestados indicaron que el desconocimiento de la ciencia en Paraguay estaba relacionado con la falta de educación. Este trabajo exploro, desde la investigación realizada en un proyecto del área de ciencias exactas y naturales financiado por el CONACyT, propuestas educativas participativas de integración y a la vez de educación de los beneficiarios.
“Ave aventura”: una propuesta educativa para el primer ciclo de EEB en el Museo de Historia Natural del Paraguay
Authors: Colmán Ramírez Francisco Javier , Yahari Hugo Daniel
Published: July 2019

La sociedad Sudamérica ha experimentado cambios en su Diseño Curricular adaptando las capacidades desarrolladas del en el aula, se toma como eje el área de Medio Natural, ya que en la experimentación es un área cuyos contenidos son un poco olvidados a la hora de desarrollados en aula, y esto la motivación de la investigación en los niños. Considerando el contexto donde se desarrollará la propuesta didáctica cabe mencionar los Fines de la Educación paraguaya que es la búsqueda de hombres y mujeres integrales. Por ello, se analiza cuarto de los Museos latinoamericanos de relevancia que se encuentran en los siguientes países Bolivia, Perú, Uruguay y Chile, Museos que cuentan con diferentes programas educativos desde jardín hasta el bachillerato, destacándose Bolivia que cuenta con una Alianza con el Museo de Ciencias Naturales de Madrid (MNCM). De allí nace la propuesta didáctica ¨Ave Aventura¨, diseño que se pretende implementar como uno de los primeros programas educativos en el Museo, que consiste en un taller con actividades relacionadas tomando tres capacidades del programa paraguayo que están vinculadas con la colección. Ave aventura es una propuesta dividida en dos fases:La primera fase es un taller con los maestros denominado Volando con la Imaginación, la fase dos es la Actividad con los niños “Ave Aventura”.
Satisfacción del estudiante de la carrera de enfermería con la formación recibida en la Universidad María Auxiliadora (UMAX), Año 2014
Authors: Portelli María Lilian
Published: July 2019

En los últimos tiempos la educación y, en especial la educación superior, pareciera ocupar el banquillo de los acusados. El aumento casi indiscriminado de instituciones de educación superior junto a la creciente demanda de la matrícula, la heterogeneidad de la misma, la movilidad de estudiantes, académicos y profesionales configuran un escenario lleno de grandes desafíos para este sector. La calidad de la misma es constantemente interpelada por una sociedad que está en constantes y acelerados cambios. En este contexto, las instituciones se ven en la necesidad de redefinir y perfeccionar la calidad del servicio educativo que ofrece, a fin de enfrentar con éxito los retos emergentes y poner en el escenario laboral a profesionales con las competencias requeridas para apostar al desarrollo del país. Para Jiménez González (2011), la satisfacción del estudiante es elemento clave en la valoración de la calidad de la educación, ya que refleja la eficiencia de los servicios académicos y administrativos: su satisfacción con las unidades de aprendizaje, con las interacciones con su profesor y compañeros de clase, así como con las instalaciones y el equipamiento. La visión del estudiante, producto de sus percepciones, expectativas y necesidades, servirá como indicador para el mejoramiento de la gestión y el desarrollo de los programas académicos.
Experiencia de hombres condenados por feminicidio
Authors: Llanes Gómez Gloria
Published: July 2019

En Paraguay, cada año alrededor de 50 mujeres son asesinadas por sus parejas o ex parejas, según las cifras oficiales de Feminicidio del Ministerio de la Mujer. Esta investigación sobre Experiencia de Hombres condenados por Feminicidio, trata de demostrar desde una perspectiva real, tomando al victimario como punto de partida para entender los factores que condujeron al hecho. Feminicidio es considerado como la ´´muerte violenta de mujeres (asesinato, homicidio o parricidio), por el hecho de ser mujeres´´ así como ´´el asesinato de mujeres por razones asociadas con su género´´.
Análisis comparativo del modelo de gestión técnica entre los Centros Educativos CEIP Pinar de San José (ESP) y el Colegio Técnico
Authors: Sosa Gómez Oscar Misael
Published: July 2019

El trabajo de investigación se divide en dos partes principales, una consistente en una revisión sistemática de bibliografía respecto a los equipos directivos y aspectos relacionados a su funcionamiento, integrantes y las implicancias de la gestión directiva, al mismo tiempo cuenta con una segunda bloque temático que trata de un estudio de caso en el que se comparan las gestiones técnicas de los directores de dos centros educativos en específico. Uno correspondiente a la Comunidad Autónoma de Madrid y el otro al Gran Asunción, Paraguay.
El apoyo familiar en el proceso de formación académica en los estudiantes
Authors: González Orrego Ninfa
Published: July 2019

Este trabajo se ha realizado en el contexto de la relación familia-escuela, específicamente con el tema del apoyo familiar en el proceso de formación académica y personal. Se centra en las variables de comunicación y participación por parte de los padres durante el proceso educativo de los estudiantes.
Extensión universitaria: su aporte en la formación de los estudiantes del último curso de las Carreras de Grado de la Universidad Iberoamericana, Sede San Lorenzo, año 2018
Authors: Conti Rosa del Carmen
Published: July 2019

Se analiza el aporte del programa de extensión universitaria que requiere la inversión de tiempo de directivos, docentes y estudiantes, planificación, ejecución y evaluación, por lo que es importante conocer más detalladamente la realidad sobre su implementación y su aporte en la formación de los estudiantes universitarios.
Consecuencias de la adicción del celular en estudiantes adolescentes de 12 a 15 años
Authors: Conti Rosa del Carmen , Paredes Leila , González Marta , Oviedo Fátima Esperanza , Bogarin Lorena , Torres Silvio Miguel
Published: July 2019

La telefonía celular está creciendo en nuestro país a pasos agigantados ya que es considerado un fuerte medio porque integra imágenes y aplicaciones, que por poseer esas características y por tener la facilidad de llegar a la mayoría de la población, se ha transformado en un arma de doble filo dada la calidad de aplicaciones que transmite sin considerar que, la mayoría de sus usuarios no tienen un adulto que les oriente en relación al uso adecuado del mismo.
Phylodynamic analysis of hepatitis delta virus genotypes 1 and 2 in the Russian Federation
Authors: Karlsen Anastasia
Published: July 2019

Hepatitis delta virus (HDV) infection has an uneven prevalence in the Russian Federation, with low infection rates in European part. But, there are several endemic regions in the country, such as Republic Saha (Yakutia), Republic Tuva and Republic Dagestan. The aim of this study was to elucidate the transmission history of HDV in the Russian Federation Materials and methods
Students’ Perceptions of Doctoral Supervision: A Study in an Engineering Program in Australia
Authors: Helfer Fernanda , Drew Steve
Published: July 2019

Aim/Purpose: The overall aim of this study was to improve our understanding of engineering student satisfaction and expectations with PhD supervision and their perceptions of the roles in a supervisory relationship.

Background: Studies on PhD supervision quality are highly valuable, mainly when they provide information on supervision experiences from students’ perspectives, rather than from supervisors’ perspectives. Understanding how PhD students think, their preferences and their perceptions of roles in a supervision process can help enhance the quality of supervision, and consequently, form better researchers and produce better research outcomes.

Methodology: The method employed in this investigation was based on a student survey with scaled and open-ended questions of 30 full-time engineering PhD students from a research institution in Australia.

Contribution: Studies that provide a better understanding of how engineering PhD students think and how they expect a supervisory relationship to be are limited. This study can be used to derive recommendations for improving supervisory relationships, particularly in engineering schools and institutions.

Findings: The majority of the students perceived most of the supervisor and student roles in close agreement with the roles described in the literature and existing codes of practice for the supervision of higher degree research students. The main reasons for dissatisfaction with supervision were identified as being the lack of involvement of supervisors in the research projects, particularly in the writing process, and the lack of supervisor’s knowledge in the field being supervised.

Recommendations for Practitioners: It is recommended that the roles of each party in a supervision process be discussed and clarified at the beginning of any PhD candidature to avoid false student expectations. The right supervisory fit should be ensured early in the candidature, and additional supervisors should be added to the team if the expertise of supervisors is deemed insufficient. The use of supervisory panels as opposed to individual supervisions to ensure that responsibilities are shared and to increase the range of advice and support available to each student is highly recommended.

Recommendation for Researchers: It is recommended that this type of research be expanded to other disciplines. It is also recommended that specific actions be taken to improve supervision and these be correlated to satisfaction rates and/or student performance.
Simplified Irregular Beam Analysis and Design
Authors: Al-Ansari Mohammed Salem , Afzal Muhammad Shekaib
Published: July 2019

This paper presents simple method to estimate the strength design of reinforced concrete beam sections based on structural safety and reliability. Irregular beam shaped sections are commonly used nowadays in the construction industry. This study reveals the simplified method to analyze and design the different irregular shaped beam sections. In this study, the selected irregular beam shaped sections are divided mainly into three groups, beams with straight edges, beams with sloped edges and circular beams. Each group contains the most commonly used beam shaped sections in that category. Six beams sections (B-1 to B-6) are selected for group-1 whereas five beam sections (B-7 to B-11) and a circular beam section (B-12) are chosen for group 2 and 3 respectively. Flexural beam formulas for three groups of reinforced concrete beams are derived based on section geometry and ACI building code of design. This study also analyzed numerical examples for some of the sections in each group category using the proposed simplified method to determine the strength design of the irregular beams. The results obtained using simplified method for all of the three groups are compared with the finite element software (SAP v2000). The percentage difference of simplified method with the finite element software ranges within 5% to 10%. This makes the simplified method for irregular shaped beam sections quite promising.
Integrated TRMM Data and Standardized Precipitation Index to Monitor the Meteorological Drought
Authors: Abdulrazzaq Zaidoon T. , Hasan Raghad H. , Aziz Nadia A.
Published: July 2019

Droughts are a major problem in Iraq especially in the Arid and Semi-Arid Lands where they are frequent and causes a great deal of suffering and loss. Drought monitoring and forecasting requires extensive climate and meteorological data which is usually largely missing in developing countries or not available in the required spatial and temporal resolutions. In this study, the drought categories were defined for the years 2000, 2005, 2010, 2015 and 2017 using the TRMM data to map the spatiotemporal meteorological drought, and the Standardized Precipitation Index (SPI) to analyze the meteorological drought at 11 stations located in Western Iraq. The SPI analyses were performed on 12-month datasets for five years. The results showed that the northeast region has the higher rainfall indices and the southwest region has the lowest rainfall. An analysis of the drought and rain conditions showed that the quantity of extreme drought events was higher than that expected in the study area, especially in the south and southwest areas. Therefore, an alternate classification is proposed to describe the drought, which spatially classifies the drought type as mild, moderate, severe and extreme. In conclusion, the integration between TRMM data SPI data proved to be an effective tool to map the spatial distribution and drought assessment in the study area.
Analysis of Indus Delta Groundwater and Surface water Suitability for Domestic and Irrigation Purposes
Authors: Solangi Ghulam Shabir , Siyal Altaf Ali , Siyal Pirah
Published: July 2019

The present study was conducted to analyze the suitability of groundwater and surface water of the Indus Delta, Pakistan for domestic and irrigation purposes based on the concentrations of arsenic (As), total dissolved solids (TDS), and chloride (Cl). Around 180 georeferenced groundwater and 50 surface water samples randomly collected were analyzed and mapped spatially using ArcGIS 10.5 software. The results were compared with their respective WHO and FAO guidelines. The analysis revealed that as in groundwater and surface water samples ranged up to 200, and 25 µg/L respectively. Similarly, the TDS in the groundwater and surface water ranged from 203 to 17, 664 mg/L and 378 to 38,272 mg/L respectively. The Cl in groundwater and surface water varied between 131 and 6,275 mg/L and 440 to 17,406 mg/L respectively. Overall, about 18%, 87% and 94% of the groundwater, and 10%, 92% and 56% of the surface waters possessed higher concentrations of As, TDS, and Cl, respectively. The higher levels of Cl in the samples are attributed to subsurface seawater intrusion in the delta. Analysis results and GIS mapping of water quality parameters revealed that in most of the delta, the quality of water was not suitable for drinking and agricultural purposes, thus should be properly treated before its use.
Comparative Analysis of Settlement and Pore Water Pressure of Road Embankment on Yan soft soil Treated with PVDs
Authors: Mamat Rufaizal Che , Kasa Anuar , Mohd Razali Siti Fatin
Published: July 2019

The application of prefabricated vertical drains (PVDs) in the road embankment construction has been successfully performed in many projects throughout the country. The simulation of finite element method (FEM) can assist engineers in modelling very complex structures and foundations. This paper presents a plane–strain numerical analysis that was performed to verify the effectiveness of the model embankment stabilised with PVD using Plaxis 2D version 8. This study employed the smear effect of permeability ratio (kr) of 3 in the PVD modelling. The data of settlement and pore water pressure in the left and right sides of road embankment were monitored for 177 days, then the data were collected and compared by a numerical simulation. The coefficient of determination (R2) was used to assess the performance of the comparative analysis. The results of numerical simulation on settlement and pore water pressure obtained a coefficient of determination of greater than 0.9 which has reached a good agreement with those of the field measurement. On other the hand, there was no significant difference in the performance between both sides of the embankment. The smear effect parameter (kr = 3) is recommended for PVD designs and can provide accurate FEM prediction.
Ağrı ilinde kaz yetiştiriciliğinin incelenmesi
Authors: ALKAN Sezai , EREN Erhan
Published: July 2019

Bu araştırma, Ağrı ilinde kaz yetiştiriciliği
yapılan işletmelerin genel yapısının belirlenmesi amacıyla yürütülmüştür.
Araştırmada Ağrı ilinin merkezinde ve ilçelerinde kaz yetiştiriciliği yapan 151
aile işletmesinde uygulanan anketlerden elde edilen veriler kullanılmıştır.
Araştırma sonuçlarına göre, yetiştiricilerin %49.67’sinin 40-59 yaş arasında,
%48.34’ünün ilkokul mezunu ve %56.29’unda ise hane genişliğinin 4-6 kişi
arasında olduğu belirlenmiştir. Yetiştiricilerin %85.43’ü kaz yetiştiriciliği
dışında başka hayvancılık faaliyetiyle uğraşmaktadır. Yetiştiricilerin %64.9’u
kaz yetiştiriciliğini tüketim alışkanlığı olduğu için yaptığını belirtmiştir.
Kaz yetiştiriciliği süresinin işletmelerin %63.58’inde 1-10 yıl arasında
değiştiği belirlenmiştir. İşletmelerin %71.52’sinde kazın dışında tavuk
yetiştirilmektedir. İşletmelerin sadece %4.64’ünde kaz dışında başka kanatlı
hayvan yetiştirilmemektedir. Yetiştiricilerin %73.51’i kaz sayısını arttırmak
istediğini belirtmiştir. İşletmelerin % 98.68’inde kuluçka makinesi
kullanılmamakta ve %49.01’inde ise dezenfeksiyon yapılmamaktadır.
Yetiştiricilerin %62.91’I kazları 5-6 yıl süreyle damızlık olarak
kullanmaktadır. Yetiştiricilerin %90.73’ü kazları 8-12 aylık yaşta kesmektedir.
Yine yetiştiricilerin %84.77’si kaz üretimine devam etmek istediklerini ve
karşılaştıkları en önemli sorunun hastalıklardan kaynaklanan kayıplar (%19.86)
olduğunu belirtmişlerdir.
Bir sera işletmesi için şebekeye bağlı ve şebekeden bağımsız rüzgâr, fotovoltaik ve jeneratör sistemlerinin teknik ve ekonomik değerlendirmesi
Authors: ÇAĞLAYAN Nuri
Published: July 2019

Bu çalışmada, bir
sera işletmesinin elektrik ihtiyacının karşılanabilmesi için şebeke, rüzgâr
(RT), güneş (FV) ve jeneratör enerji sistemlerinin modelleme ve bilgisayar
benzetimleri yapılmıştır. Bilgisayar
benzetiminde işletmenin elektrik yükü günlük 369.52 kWh olarak tespit
edilmiştir. Ayrıca bu
sistemlerin ekonomik fizibilitesi birim enerji maliyetine (EM) göre
değerlendirilmiştir. Benzetim (Simülasyon) sonuçlarına göre, fotovoltaik ve rüzgâr
enerji sistemlerinin enerji maliyetleri sırasıyla 0.084 ve 0.059 $ kW-1 olmaktadır. EM sonuçlarına göre, fotovoltaik sistem, rüzgâr
enerji sistemine göre daha pahalıdır. Yıllık enerji üretim
miktarları incelendiğinde ise, rüzgâr enerji sistemi
fotovoltaik enerji sisteminden 3.1 kat daha fazla enerji üretebilmektedir. Öte
yandan, dizel jeneratörün enerji maliyeti (0.554 $
kWh-1) fotovoltaik sistemle birlikte bu işletme için en pahalı enerji kaynağıdır. Çalışmada ayrıca
zararlı gaz emisyon değerleri de araştırılmıştır. Rüzgâr enerji sistemi
kurulursa, yılda 34742 kg CO2, 151 kg SO2 ve 73.7 kg NOx
salınımı önlenebilecektir. Elde edilen
sonuçlara göre sera işletmesi için en uygun sistemin rüzgâr enerjisi olduğu
görülmüştür.
Trakya bölgesi canavar otlarının (Orobanche cumana Wallr.) ayçiçeğinin gelişimi üzerine bazı etkilerinin belirlenmesi
Authors: ÜDER Fatih , DEMİRBAŞ Sefer
Published: July 2019

Canavar otu (Orobanche
cumana Wallr.) parazit bitkisi fotosentez yeteneğinden yoksun olmasından
dolayı ayçiçeği (Helianthus annuus L.)
üretim alanlarında enfeksiyon seviyesine bağlı olarak ciddi verim kayıplarına
neden olmaktadır. Bu çalışmada, canavar otuna dayanıklı (LG5582) ve duyarlı
(Özdemirbey) ayçiçeği çeşitlerinin 2003-2016 yılları arasında Tekirdağ,
Kırklareli ve Edirne illerinin ayçiçeği üretimi yapılan bazı tarlalarından
toplanmış canavar otu enfeksiyonundan ne derecede etkilendikleri
belirlenmiştir. Öncelikle, toplanan canavar otu tohumlarının in vitro ortamda çimlenme kabiliyetleri
belirlenmiştir. Sonrasında in vivo
bitki yetiştirme ortamında canavar otu fidelerinin toprak yüzeyine çıktığı gün
ayçiçeği bitkilerinden örneklemeler yapılarak kök/gövde uzunluğu, kök/gövde yaş
ağırlığı, kök/gövde kuru ağırlığı, spesifik yaprak alanı (SLA) ve canavar otu
enfeksiyon seviyesi belirlenmiştir. Elde edilen sonuçlara göre, duyarlı ayçiçeği çeşidinde en yüksek hasarın 2016
yılında toplanan canavar otu tohumlarından kaynaklandığı, 2003 yılında toplanan
tohumlarının geçen süre zarfında hala çimlenebiliyor ve duyarlı ayçiçeği
çeşidinde enfeksiyon yaratabiliyor olduğu, ayçiçeği bitkilerinin gelişimleri
incelendiğinde enfeksiyon seviyesinde meydana gelen artışın kök uzunluğu,
gövde yaş/kuru ağırlığında artışa SLA değerinde ise azalmaya neden olduğu.
Ayçiçeği fidelerinin gövde uzunluğu ve kök yaş/kuru ağırlığında meydan gelen
değişimlerin ise enfeksiyon ile ilişkilendirilemeyeceğini saptanmıştır.
Difusi Produk Bioteknologi “Probiotik” Untuk Meningkatkan Produksi Ternak Ruminansia di Desa Lelede Kecamatan Kediri, Lombok Barat
Authors: Ulfa Arafatul , Akbar Mahfud , Ali Muhamad , Akbar Jihad
Published: July 2019

The community of Lelede Village, Kediri District, West Lombok Regency, mostly cultivate goats and cattle. However, the cultivation of both types of livestock is still done traditionally using grass and agricultural waste as feed. From that case, the addition of microorganisms which has the ability to digest fiber is very important in order to optimize the digestion process of the feed. Probiotics are certain microorganisms that can help digestion and can minimize the presence of disease. In this activity the production and the use of probiotics has been diffused to improve the livestock production performance in Lelede Village, Kediri District, West Lombok Regency. The activity began with socialization of probiotics, training of probiotics production, and its used for ruminants. The training material consisted of the process of making probiotics started from measuring the dosage of ingredients, making inoculum, until the production of probiotics in fermentors. For the training, 35 farmers have been involved. The probiotics produced are then distributed to farmers for later given to livestock either through feed or drink water.
Pengembangan Modul Perubahan Lingkungan dan Daur Ulang Limbah Berbasis Discovery Learning Melalui Media Google Classroom
Authors: Muttaqin Ainul , Fatirul Achmad Noor , Hartono Hartono
Published: July 2019

Pembelajaran biologi lebih diorientasikan pada pembelajaran yang mengutamakan pengalaman belajar bagi peserta didik. Hal ini bisa diperoleh melalui rangkaian kegiatan interaksi aktif teman sejawat dan lingkungan belajar peserta didik. Pembelajaran biologi perlu dikembalikan pada pembelajaran yang sebenarnya yaitu pendekatan produk dan proses pembelajaran dengan cara melibatkan secara aktif seluruh peserta didik dalam mengelola serta mengembangkan keterampilan berfikir kritis, keterampilan proses, mengembangkan pengetahuan maupun pengalaman peserta didik seperti pengembangan pembelajaran berbasis discovery learning. Sehingga pembuatan modul ini dirasa sangat penting untuk dikembangkan. Tujuan penelitian pengembangan ini adalah untuk mengetahui tingkat karakteristik, kelayakan dan keefektifan modul pembelajaran biologi berbasis Discovery Learning pada materi perubahan lingkungan dan daur ulang limbah sesuai dengan kebutuhan peserta didik di kelas X SMA Muhammadiyah 1 Gresik melalui media google classroom. Dalam pengembangan produk ini menggunakan teori Borg and Gall yang terdiri dari (1) Penelitian pendahuluan dalam rangka mengidentifikasi masalah dan potensinya. (2) Proses pengumpulan data. (3) Pembuatan desain produk. (4) Validasi desain. (5) Revisi desain. (6) Uji coba produk. (7) Revisi produk. Sedangkan model pengembangannya menggunakan model pengembangan produk diadaptasikan dari model ADDIE, yaitu Analyze, Design, Develop, Implement and Evaluate. Berdasarkan pada hasil data kajian analisis yang diuraikan sebelumnya, dapat disimpulkan bahwa produk pengembangan modul pembelajaran biologi SMA kelas X pada materi perubahan lingkungan dan daur ulang limbah sangat layak untuk diaplikasikan dalam pembelajaran pada peserta didik SMA Muhammadiyah 1 Gresik. Dasar kelayakan ini diambil dari hasil penilaian para ahli baik ahli media, ahli isi materi, dan penilaian teman sejawat. Selain memang layak, modul ini dikembangkan menggunakan pendekatan pembelajaran discovery learning dan dilakukan melalui aplikasi online google classroom dengan tujuan utama adalah pembelajaran yang aktif dan kreatif dari peserta didik.
Narrativas sobre a ação do estado na história da colonização de Campo Mourão (1900-1950)
Authors: Weber Astor , Junior Jorge Pagliarini
Published: July 2019

O texto objetiva, por intermédio da análise comparativa entre os artigos, as dissertações, as teses e a historiografia local, compreender porque algumas narrativas explicam de forma distinta a participação do Estado na história da colonização da região de Campo Mourão (1900-1950). A análise leva em consideração o período da produção dessa escrita e o lugarsocial e cultural de fala desse leitor-autor. O primeiro grupo é composto por geógrafos (1950-1990), o segundo grupo também por geógrafos (2000-2010), o terceiro grupo é formado por um historiador (2008) e um antropólogo-historiador (1990-2000) e o quarto grupo é composto pela historiografia local (1975-2010). Observou-se que a oposição das interpretações entre os geógrafos é influenciada pelo diferente período e as implicações teórico-metodológicas usadas na sua produção. Já a historiografia local se aproxima mais das interpretações dos geógrafos das décadas de 1950 a 1990 do que ao das décadas de 2000 a 2010. Portanto, nesse caso não é somente o período de produção que se deve levar em consideração para comprender as diferentes interpretações, muito mais o local de pertencimento social e cultural de produção desses grupos.
Pembuatan Sistem Kontrol Sliding Door untuk Rumah Tinggal
Authors: - Sir Anderson
Published: July 2019

The sliding door is a type of door that works by sliding the door to the right or to the left. The sliding door is a type of door that is suitable for use in a room with small volume, because the sliding door does not require a large space. lack the sliding door when the door has been closed, lack the sliding door when the door has been closed, there still exists a gap between the open doors and walls so that air can be in and out freely. with the construction of the door using the hinge mechanism, can minimize these conditions. To make the sliding door works automatically, the authors make a set of control system that uses an analog system and the concept of open-loop control system. “dc motor” is used as drive for the door and “central lock actuator” as locking doors. On the control circuit voltage source used is equal to 12V. Control circuit components used are double circuit push button (NO and NC), 12V relay 8 feet, limits switches, motor DC of power windows, central lock actuator. The components were assembled for the purpose of changing the polarity of the DC motor is regulated by a relay mechanism. By changing the polarity of the dc motor, the motor can rotate to the left and to the right, so the door is connected to the motor would be moves to open and close according to the motor movement.
Perancangan, Pembuatan dan Pengaturan Temperatur Pemanas Alat Uji Konduktivitas Termal
Authors: - Sir Anderson , - Sirnikson -
Published: July 2019

Severally material thermal character momentous deep arithmetic balans energy on hot transfer application. Data of thermal character for some type substance and significant have available deep tabular or graph on hot transfer textbooks and material knowledge and hand book. Along with epoch progress, there are many found new materials. By undertaking examination on tool tests conductivity significant this, conductivity significant examinee can be known. Examination is done to significant non metal in this case glass. Examination result points out kecendrungan descent of thermal conductivity significant to temperature ascension. Over and above mass factor, chemical composition, and crystal structure; processing factor determine material thermal conductivity price. To do thermal conductivity examination significant needful temperature which constant. Temperatures regulatory series manage tension of current source with action controls two on off's positions bases accepted DC tension
Studi Analisis Pengaruh Debit Air Terhadap Daya yang dihasilkan Pembangkit Listrik Tenaga Mikro Hidro (PLTMH) di Kecamatan IV Nagari Bayang Utara
Authors: - Nasrul -
Published: July 2019

In the district IV Nagari of North Bayang there are rivers that have a large water flow. Given its geographical position, these rivers has a large enough height difference. These rivers provide great opportunities for the development of electric energy generation in microscale powerplants.This District only have 2 villages that reserved the electricity, while others not covered due to the difficult path impassable and distances. So as to provide the electricity needs of society, the government in collaboration with the PNPM Mandiri established several microhydro powerplants (PLTMH), because of the potential for water in this place is quite large and abundant.PLTMH in this District is among PLTMH Muaro Aie 72.5 kW, PLTMH Pulai Indah 60 kW, PLTMH Bayang Janiah 15 kW, PLTMH Pancuang Taba 75 kW, PLTMH Limau-Limau 25 kW and PLTMH Ngalau Gadang 25 kW. By doing this analysis study can be known the potential of water flow on the PLTMH Muaro Aie and Pulai Indah. Due to the large potential of water flow present then the power raised also will be bigger, and new plants can be built or added to distribute the power to other areas that have not been fed by electrical energy.
Pengaruh Sudut dan Jari-Jari Saluran Menikung terhadap Konsentrasi Aliran Sedimen Suspensi arah Transversal
Authors: - Chairul Muharis
Published: July 2019

The change in channel dimension has a great effect on the flow hydraulic parameters. Likewise, the angle and radius of the bend are not the same will also affect the concentration of suspended sediment flow. To determine the effect of angle and radius of the bend, the measurement of susupended sediment concentration was done at 4 (four) location in Mataram irrigation channel curve. The four locations describe 2 channels having relatively the same angle but having different radius, and 2 (two) channels having the same relative radius but having different angles. Measurement of suspended sediment concentration in tranversal direction is done some depth point used by opcon probe. The results of the research for different angle of bend shows that from the interance to the end of the channel bend so the trend of suspended sediment concentration value are decreases. After the end of the channel bend started there is no more the angle influenced, the trend value of suspended sediment concentration are constant. As for the different radius, the value of suspended sediment concentration is still relatively the same and there is no change significantly. This shows that the relation or influence between the length of the radius of the bend with the value of the suspended sediment concentration is not visible
Rancang Bangun Sistem Pemantauan Infus dan Tekanan Darah pada Pasien Rawat Inap secara Real Time
Authors: - Vera Veronica , - Rahmadi Kurnia
Published: July 2019

The problems that often arise in inpatients, especially those that need special handling such as infusion fluids should be given is often the occurrence of negligence in the infusion bottle examination is good condition of fluids in infusion bottles and the number of droplets per minute that is not appropriate. In addition, the patient will also be disrupted when the nurse should take care of the patient's blood pressure periodically. To overcome these problems need to be made a system that can monitor all of it in real time.This system design process requires a hardware and software that is integrated in such a way that it can be used to monitor the infusion and blood pressure of the patient. The main hardware required is the infrared sensor and the pressure sensor where the sensor will be controlled by the microcontroller device which the results can be sent to the monitoring computer wirelessly.           From the overall testing of the design that has been made, it can generally be applied but there are still shortcomings that occur in measuring instruments, especially blood pressure gauges where the average error occurred in the measurement of systolic pressure of 8.42% and the average error that Occurs in diastolic measurements of 4.90% and on data delivery there is a significant delay spike when given a barrier.
Monitoring Suhu Proses Sangrai Biji Kopi
Authors: - Roza Susanti , Aidha Zas Ressy , Satrio Fedri Tri
Published: July 2019

Temperature set of the coffee bean roasting to get the roasting temperature of arabica using thermocouple temperature cencor. Temperature monitoring is controlled by microcontroller. The suitable temperature set of roasting process determine the temperature of three conditions, they are light roast, medium roast, and dark roast. Roasting temperature set of the coffee bean have a goal to get the best quality of coffee bean.
Perancangan Sistem e-Library Berbasis Web Jurusan Teknik Elektro Politeknik Negeri Padang
Authors: - Nasrul -
Published: July 2019

Data communication technology allows the building of a network of  computers with online applications.  With the Padang  State  Polytechnic  library  system  that  still  uses  a manual  system in the form of  books  and  cards – cards that contain data – data book is considered not efficient anymore, so it takes a library of WEB - based information systems. With the utilization of internet technology in tended for delivery and the need for rapid information retrieval, facilitate student and informed the user in the title of books desired, assist the Polytechnic library Country Meadow in logging the books, because of the internet as a very broad network is an effective and efficient means for this application.