bluuebunny/crossref_metadata_2025 huggingface dataset:
Adaption of the Loneliness in Intimate Relationships Scale (LIRS) to Turkish
Authors: EKŞİ Halil , KISRIK Sevda
Published: December 2023

The aim of this study is to investigate how loneliness is experienced in intimate relationships adapt, validate and assess the reliability of the Loneliness in Intimate Relationships Scale developed by Rokach, Sha'ked and Ben-Artzi (2022) for Turkish culture. The study group consists of 363 participants (229 females, 124 males) selected through an appropriate sampling method, ranging in age from 18 to 54.The translation-back-translation method was used during the process of translating the scale into Turkish. This scale consists of three factors with 14 items: separation, hurt, and guilt. The factor structure of the original scale was examined through confirmatory factor analysis, and it was found that the model exhibited acceptable fit. According to the analysis results, item factor loadings ranged from .46 to .64, showing variability. The reliability analysis resulted in a Cronbach's Alpha coefficient of .85 to establish the validity of the scale for the sample, the Beck Depression Inventory and the Experiences in Close Relationships Revised-II Scale were administered to a total of 123 individuals. Based on the analysis, it can be said that the original scale has acceptable criterion-related validity based on its positive relationship with anxious attachment and depression. The results of the study indicate that the Turkish version of the Loneliness in Intimate Relationships Scale has validity and reliability properties, making it suitable for use in scientific studies conducted in Türkiye.
Metabolic perturbations as trigger and driver of disease in hypertrophic cardiomyopathy
Authors:   , Nollet Edgar Elbert
Published: December 2023

Hypertrophic cardiomyopathy (HCM) is a frequently occurring disease of the heart muscle, characterized by asymmetrical left ventricular hypertrophy and diastolic dysfunction. In approximately half of all patients the disease is caused by mutations in genes encoding sarcomere proteins. These patients are referred to as genotype-positive (G-positive). In the other half of patients the disease is not caused by genetic mutations (genotype-negative patients; G-negative). Despite the fact that mutations in sarcomere proteins cause HCM in G-positive patients there is remarkable variation in the extent to which mutation carriers develop HCM. One mutation carrier may develop severe hypertrophy and heart failure at young age, while another remains asymptomatic until old age. Thus, the presence of a mutation itself is not sufficient to cause disease. Clinical studies suggest that traditional cardiovascular risk factors such as obesity and diabetes mellitus type II may contribute substantially to disease penetrance and severity of HCM. These factors have a considerable negative impact on cardiac metabolism. In part 1 of this thesis we explore how metabolic perturbations at the systemic level are involved in triggering G-positive HCM. Hereto we provide an overview of clinical literature and design a theoretical framework outlining cellular mechanisms via which obesity-associated metabolic perturbations may trigger HCM. Subsequently we tested this framework in mouse models of G-positive HCM. Our studies showed that in certain mouse models it is possible to indeed trigger HCM by feeding an unhealthy diet, which was accompanied by marked metabolic alterations in the diseased heart. In part 2 of this thesis we study how metabolic perturbations are related cardiac remodeling in HCM. To this end we used myectomy tissue samples of patients with HCM. Structural and functional analyses showed that mitochondrial dysfunction was linked to disruption of cardiomyocyte architecture. Additionally, only in G-negative patients there was a link between septal hypertrophy and mitochondrial dysfunction. In line with this observation, multi-omic analyses revealed contrasting patterns of metabolic alterations in relation to cardiac remodeling in G-positive and G-negative patients with HCM. This suggests that divergent disease mechanisms drive disease in these two patient groups. Lastly, in part 3 we discuss several methodological aspects and considerations in the field of (animal-free) basic cardiac science.
Metabolic modeling of microorganisms and dynamics of microbial communities in the food industry
Authors:   , Mendoza Farías Sebastián Nelson
Published: December 2023

In this thesis, we initially evaluated a wide range of reconstruction tools to determine their optimal performance in various cases. By utilizing the appropriate reconstruction tools, we successfully created a high-quality, genome-scale metabolic model for Lactobacillus delbrueckii subsp. bulgaricus, a bacterium commonly employed in yogurt production. Furthermore, we incorporated proteomic data into the model, acquired from two relevant conditions: growth on casein or amino acids. Through the incorporation of enzymatic capacity constraints into the model, we captured the emergence of glucose secretion as a system property, a phenomenon not discernible through the genome-scale model alone.
Concluding our study, we introduce two innovative approaches to simulate the dynamics of co-evolved microbial communities. These methodologies are particularly suitable for species that release costly compounds into the surrounding medium due to co-evolution, as observed in the context of yogurt production. With this thesis, we have propelled the domain of systems biology as applied to the food industry, utilizing yogurt production as our focal case study.
To List or Not to: Why Do Companies Deny Financing through Capital Market in Bangladesh?
Authors: Akter Faima , Mahmud Imran , Hossain Md. Iqbal
Published: December 2023

This study aims at figuring out the key reasons responsible for
inhibiting companies to go for IPO. For the purpose, 100
privately listed companies situated in Dhaka had been
approached and 15 companies responded. To substantiate
the views of the companies, interviews from academician,
merchant bank authorities, capital market journalist forum,
and regulators were taken. In total, 25 Key Informant
Interviews (KIIs) were conducted for the study. A focus group
discussion (FGD) was arranged consisting 30 representatives
from different merchant banks. To present the findings of the
study, a thematic analysis approach was chosen where initial
codes from the interviews and FGD were transformed and six
key themes: macro-environment deterrent, institutional
limitations, firm specific barriers, capital market deterrents,
corporate governance code 2018, and money market
deterrents were identified as the main factors of IPO
avoidance by eligible companies. The study revealed that lack
of coordination among relevant policy makers, few clauses of
corporate governance code 2018, costly and lengthy IPO
issuance process, insignificant tax gap, bank’s lenience
towards loan defaulters, loan rescheduling facility of banks,
lack of knowledge regarding capital market products, and
compliance related issues are considered the most crucial
reasons for IPO avoidance.
Macroeconomic Influence on the Balance of Payments of Bangladesh
Authors: Farzana Nahid
Published: December 2023

The present study investigated how the macroeconomic
factors have affected the balance of payments (BOP) of
Bangladesh using the time series data from 1990 to 2021.
The study found that balance of payments has been greatly
affected by the exchange rate of currencies (EXR), growth
rate of the gross domestic product (GDP), the foreign direct
investment (FDI) and the balance of trade (BOT) during the
period. Various pre and post estimation tools and techniques
have been employed followed by running of regression
models utilizing the STATA software to confirm the model
suitability and to consider the model outcomes to the
researchers, policy makers and the enthusiastic readers for
further studies and decision making. The study suggests that
the efficient implementation of government policies is vital in
determining how the economy of a nation is formed and to
perform. It emphasizes how important it is to create a friendly
atmosphere for foreign investments because these
investments could have an impact on the BOP and economic
growth of the country.
Pengenalan Literasi Akuntansi Syariah Sejak Usia Dini Pada Guru-Guru TK RA Al-Hidayah Pekanbaru
Authors: Oktaviani Rona Naula , Rahman Firdaus Abdul , Setiawan Rahmat , Ningsih Widiya Ningsih
Published: December 2023

Financial education is an important aspect in forming a quality generation, especially children. This service activity aims to increase teachers' understanding of sharia accounting literacy from an early age. This activity involved the participation of teachers at Kindergarten RA Al-Hidayah Pekanbaru. The problem is the lack of understanding and knowledge about sharia accounting literacy faced by teachers. This will affect their ability to integrate sharia accounting literacy into the curriculum and daily learning. The methods used are socialization, material presentations, and question and answer discussions. The conclusion from this activity is that there is still a lack of sharia accounting literacy among teachers. So, with this service activity it is hoped that it can increase teachers' understanding and knowledge of sharia accounting literacy and integrate it into daily learning, thereby helping children develop a good understanding of sharia accounting principles. So, it is recommended to make a positive contribution in forming a generation that understands and applies sharia accounting principles in financial management in order to build a strong foundation for future generations.
The Moderating Role of Sustainability Disclosure in the Association between Tax Avoidance and Cost of Debt
Authors: Firmansyah Amrie , Fauzi Irfan , Geno Muchamad Rizal Pua , Prakosa Dani Kharismawan , Purwaka Adhitya Jati
Published: December 2023

Company funding can derive from debt and shares. Managers' funding decisions have an impact on the costs that the company must bear. Even though it has high risks and many requirements, managers use much debt in company funding. The company must bear the debt costs associated with this funding. This research examines the effect of tax avoidance on the cost of debt. This research also uses sustainability disclosure as a moderating variable. This research uses manufacturing company financial report data from www.idnfinancials.com from 2016 to 2020. Based on purposive sampling, the total number of observations can be used in this research is 276. Hypothesis testing was carried out using multiple linear regression analysis for cross-section data. This research concludes that tax avoidance positively affects the cost of debt. This research also finds that sustainability disclosure strengthens the positive influence of tax avoidance on the cost of debt. This research contributes to providing literature on the role of sustainability implemented in companies in one of the developing countries. This implementation can be associated with managerial decisions that may not always align with the interests of company owners.
PROTOTYPE SISTEM OILY WATER SEPARATOR OTOMATIS PADA KAPAL MENGGUNAKAN METODE DECISION TREE BERBASIS MIKROKONTROLER
Authors: Ghilman Ahmad Faza  , Muhammad Fikri Fathurrohman  , Purwidi Asri  , Anggara Trisna Nugraha  , Perwi Darmajanti
Published: December 2023

Industri pelayaran rentan terhadap pencemaran laut berupa limbah minyak saat limbah cair dibuang dari kapal ke laut. Oleh karena itu diperlukan suatu alat yang digunakan untuk memisahkan air dan minyak, alat tersebut disebut OWS (Oil Water Separator). Penelitian ini melanjutkan penelitian sebelumnya tentang pengujian dan desain OWS untuk pemisahan air/minyak di kapal. Pada penelitian ini digunakan OWS untuk memisahkan air dan minyak pada 15ppm, jika kadar air kurang dari 15ppm maka dapat langsung dibuang ke laut. Pada penelitian ini dilakukan OWS dengan sensor kekeruhan yaitu mengklasifikasikan antara air dan oli dengan set point maksimum pada saat air kurang dari 25 NTU, dan sensor TDS digunakan untuk mengukur kadar ppm dalam air dengan set point. ini dapat melepaskan ke laut jika kurang dari 15ppm. Dan juga menggunakan komunikasi LoRa untuk mengirim data sensor dari pemancar ke penerima untuk komunikasi nirkabel. Sementara itu, metode pohon keputusan digunakan untuk mengklasifikasikan keluaran agar sesuai berdasarkan nilai-nilai sensor yang digunakan.
Dedicación y apoyo a la autonomía: Competencias de deportistas y asesores de carrera dual para gestionar el solapamiento de competiciones y exámenes
Authors: Miró Moyà Salvador Lluís , Ramis Laloux Yago , Torregrosa Álvarez Miquel , Pérez-Rivases Andrea , Regüela Sáez Susana
Published: December 2023

El objetivo de este estudio es explorar las competencias percibidas como más importantespor deportistas-estudiantes y asesores de carrera dual para gestionar conéxito el solapamiento de competiciones y exámenes. Participaron 184 deportistasestudiantesagrupados de acuerdo al nivel académico (i.e., educación secundaria obligatoria,bachillerato y universitarios) y 26 asesores de carrera dual de institucionesacadémicas y deportivas. Los datos se analizaron a partir de un análisis de respuestamúltiple. Los deportistas-estudiantes identificaron la dedicación, la capacidad depriorización y la capacidad de gestionar las situaciones estresantes como las competenciasmás importantes para tener éxito durante el solapamiento de competiciones yexámenes. Por su parte, los asesores de carrera dual identificaron como más importantela capacidad de estimular la autonomía de los deportistas-estudiantes durantesu carrera dual. Este estudio apunta que hay una serie de competencias transversalespara que los deportistas-estudiantes gestionen el solapamiento de exámenes y competiciones,mientras que otras competencias dependen de la etapa académica en laque estén. Futuras investigaciones deben ir dirigidas a profundizar en el estudio delas competencias para gestionar situaciones concretas de la carrera dual y en la creaciónde programas formativos para asesores de carrera dual.
Estudio del éxito académico de un modelo universitaro de carrera dual en deportistas -estudiantes según género, nivel de estudios y deporte
Authors: Sánchez-Pato Antonio , Conde Pascual Elena , Meroño García Lourdes , Arias Estero José Luis , Alfonso García-Roca Juan
Published: December 2023

La carrera dual representa un reto para las universidades europeas que necesitannuevas vías de reorganizar el conocimiento, reglas y modelos de aprendizaje queofrecen a sus deportistas-estudiantes para conseguir una carrera académica exitosaa la vez que su desarrollo deportivo. El presente trabajo tiene como finalidad conocerel éxito académico de un modelo universitario de carrera dual de deportistasestudiantesen general y según género, nivel de estudios y tipo de deporte. Participaron139 estudiantes-deportistas (91 hombres y 48 mujeres), que permanecieronacadémicamente activos (se presentaron a exámenes) durante el curso 2015-2016.El diseño fue cuasi-experimental, longitudinal a través del que se aplicó el modelode carrera dual. Su influencia se evaluó sobre la tasa de éxito (número de créditosmatriculados, frente a los superados). Los resultados mostraron que la tasa de éxitofue elevada (72,83%), pero el alumnado de género femenino, estudiantes de gradoy deportistas de deportes de raqueta obtuvieron valores significativamente máselevados. Estos resultados podrían significar que el modelo aplicado soluciona losdesencuentros presentes hasta la fecha en los programas de apoyo al deportista enlas universidades y, por tanto, les ayuda a superar las barreras para facilitar unaconciliación adecuada entre vida deportiva y académica.
Tipos de motivación y su relación con las expectativas de compaginar deporte y estudios en jóvenes jugadores de fútbol
Authors: López Chamorro José M. , Moreno Castellano Rubén
Published: December 2023

Dentro del contexto de las carreas duales, este estudio tiene como objetivo explorarla influencia que tiene sobre los tipos de motivación y de pasión hacia eldeporte la importancia que dan futbolistas jóvenes no solo a conseguir futuros logrosen su vida deportiva, sino también la importancia que dan a conseguir futuroslogros en el ámbito académico. En el estudio participaron 478 futbolistas jóvenesde élite que rellenaron los cuestionarios basados en los modelos teóricos propuestos.El análisis de regresiones muestra que dar importancia a desarrollar una carreraacadémica en un futuro influye negativamente en el desarrollo de la amotivación yla pasión obsesiva y tendría un efecto positivo sobre el desarrollo de la motivaciónautónoma hacia su deporte. Además, los resultados muestran que percibir comoimportante conseguir futuros logros en la vida deportiva tiene una influencia positivasobre la pasión armoniosa y negativa sobre la amotivación. Estos resultadospodrían apoyar que el desarrollo de una vida académica podría tener un impactodirecto sobre variables psicosociales relacionadas directamente con el desarrollodeportivo de los deportistas y las habilidades utilizadas en la esfera deportiva.
Carrera Dual en Deportistas de Alto Nivel Españoles: la importancia del apoyo social familiar en el ámbito académico
Authors: Moreno Castellanos Rubén , López Chamorro José M. , López De Subijana Cristina
Published: December 2023

Compaginar estudios superiores y el deporte de élite (Carrera Dual; CD), exigea los deportistas de alto nivel (DAN) un sobreesfuerzo físico y psicológico difícilde gestionar. La realización de estudios superiores somete a los estudiantes a intensosmomentos de estrés, por lo que el presente trabajo trata de centrarse en elpapel que juega la familia de estos deportistas, única y exclusivamente en el ámbitoacadémico, con el fin de conocer hasta qué punto el apoyo familiar puede ayudarlosa gestionar adecuadamente esta faceta menos explorada. La metodología utilizadaen este estudio fue cualitativa y el análisis de contenido de las 7 entrevistas revelanque los deportistas que poseen un mayor capital cultural (sobre todo padrescon estudios superiores), así como aquellos que eligen estudios desvinculados deldeporte, parecen tener una mayor percepción de apoyo social percibido por partede la familia y, en consecuencia, sensaciones de estrés más atenuadas en el ámbitoacadémico.
Acciones técnico-tácticas y físicas defensivas del portero alevín en fútbol-7
Authors: Jara Cortina Daniel , Ortega Toro Enrique , Gómez Ruano Miguel Ángel , Sainz de Baranda Andújar Pilar
Published: December 2023

El objetivo del presente estudio fue analizar el comportamiento técnico-táctico y físicodefensivo del portero de fútbol en categoría alevín. Mediante la creación de unsistema de categorías y siguiendo la metodología observacional se analizaron 902situaciones defensivas realizadas en 35 partidos del campeonato nacional de seleccionesregionales alevín de la temporada 2016/2017. Las variables estudiadas fueronla acción técnica realizada por el portero, la acción física (desplazamiento, caída, saltoy estirada), zona de la portería donde termina el disparo, zona de intervención delportero y gol. Se realizó un análisis descriptivo. Los resultados muestran que la accióntécnica más utilizada es el blocaje junto al desplazamiento derecho e izquierdo.A su vez, se observó una baja frecuencia en las acciones físicas defensivas de salto,caída y estirada. La zona más utilizada por el portero para jugar fue el área pequeña,mientras que las zonas bajas de la portería (1, 2 y 3) fueron las zonas donde más golesencajaron los porteros. Las zonas bajas y laterales (1 y 3) son las zonas más utilizadasen los disparos en busca del gol. Este análisis puede servir como referencia para eldesarrollo de las capacidades técnico-tácticas en esta etapa del deportista.
Esfuerzo percibido diferenciado en árbitros y asistentes de fútbol de tercera división durante partidos oficiales
Authors: Ozaeta Beaskoetxea Eñaut , Castillo Alvira Daniel , Cámara Tobalina Jesús , Yanci Irigoyen Javier
Published: December 2023

Objetivo: El objetivo de este estudio fue describir el esfuerzo percibido diferenciado(dRPE) y la carga percibida diferenciada (dRPE CP) en árbitros de fútbol durantepartidos oficiales. Método: Noventa árbitros clasificados en tres grupos atendiendoa su rol/categoría: árbitros de campo de tercera división (AC3, n = 31), árbitrosasistentes de tercera división (AA3, n = 26) y árbitros de división preferente queejercen de forma puntual de asistentes en partidos de tercera división (AApref, n= 33). Los participantes declararon el dRPE (RPEres = esfuerzo percibido respiratorioy RPEmus = esfuerzo percibido muscular) mediante la escala 0-10 de Fosteral final de la primera parte, segunda parte y el total al final del encuentro. El dRPECP (RPEres CP y RPEmus CP) fue calculado multiplicando el valor de dRPE porla duración (min) del partido. Resultados: Todos los grupos declararon un mayordRPEy dRPE CP en la segunda parte respecto a la primera (p < 0,01). Sin embargo,los valores de RPEres y de RPEmus de la segunda parte no fueron significativamentediferentes (p > 0,05) a los valores declarados del total del partido. Por otrolado, todos los grupos declararon un mayor RPEmus que RPEres (p < 0,01 o p <0,05). Conclusión: Parece ser que el arbitraje en el futbol tiene una alta implicaciónmuscular por lo que los entrenadores y preparadores físicos de árbitros deberíandiseñar entrenamientos específicos para mejorar su capacidad neuromuscular.
Exploration of a New Zakat Management System Empowered by Blockchain Technology in Malaysia
Authors: Nazeri Amelia Nur Natasha , Mohd Nor Shifa , Abdul Rahman Aisyah , Abdul Majid Mariani , Ab. Hamid Siti Ngayesah
Published: December 2023

Purpose — This paper aims to examine the implementation of blockchain technology in zakat management and determine how it will work in the context of Malaysia. Although zakat institutions in Malaysia use technology, confidence in the efficiency of the zakat fund is still an ongoing issue. Therefore, the potential of blockchain technology for improving the zakat management system is examined.
Design/Methodology/Approach — An exploratory study involving two informants with expertise in blockchain technology and Islamic finance was conducted to investigate how the application of blockchain in the zakat management system will accelerate the future implementation and potential of zakat management in Malaysia.
Findings — This research finds an accord between the features of blockchain technology and the objectives of zakat. The features are transparency, traceability and security, which align closely with the goals of zakat. As such, a new model has been proposed for the zakat management system, one empowered by blockchain technology that harmonises with the existing system and enhances these elements.
Originality/Value — This research can motivate zakat institutions in Malaysia to implement blockchain technology in their zakat management systems by using the proposed model. The research shows the synchronisation of blockchain principles with zakat, which would build trust and confidence.
Practical Implications — The discussion on how blockchain can be embedded in the existing zakat management system will contribute towards enhancing zakat management in Malaysia and improve the performance of zakat institutions, enabling them to better serve the community. Given the scarce literature on blockchain adoption in zakat management, this study can spur further research and discussion within this area.
Effects of the number of people, temperature, relative humidity, and CO2 parameters on indoor air quality in higher education institution classrooms
Authors: Ateş Ergun , Khameneh Elham Talebi
Published: December 2023

This study involved the measurement of air temperature, relative humidity, and CO2 levels in both open and closed circumstances of windows and doors, both indoors and outdoors, during educational activities in a higher education institution classroom. Air temperature and relative humidity measurements were found to be within the range of 21.36 to 26.97°C and 42.94 to 55.16%, respectively. These values have been determined to be within acceptable comfort levels, according to the literature. The CO2 concentration has been determined to increase with the number of people in the classroom and, in some cases, exceed the level of 1000 ppm, which is accepted as a general limit value, before the end of the course period. It has been determined that if the experiment is not terminated when the CO2 level rises above 1000 ppm, the CO2 level will reach even higher values depending on the elapsed time. The maximum level of CO2 was measured at 1404 ppm among the CO2 measurement data recorded before the end of the experiment. In addition, it has been determined that as the outside air intake increases, the concentration of CO2 accumulated inside decreases. This finding suggests that ventilation is necessary in fully enclosed spaces. The number of people in the class has been determined to be 35 in order to be safe in terms of CO2 levels in the activities carried out in the classroom where the research was carried out.
Manjari - The Curse of her Widowhood, the Pangs of her Bodily Hungers, and the Pain of her Living all Alone in Shashi Deshpande's 'Moving On'
Authors: Singh Ravindra Kumar
Published: December 2023

Moving on highlights the alienation and loneliness of a young widow, the curse of her widowhood, the pangs of her bodily hunger and the pain of her living all by herself. Manjari, the novel's protagonist, faces new dilemmas that Sarita, Indu, Jaya, Urmi, Sumitra, and Madhu have never experienced.
Avaliação da aprendizagem na educação infantil e os contextos empobrecidos
Authors: Matiazzi Shellen de Lima , Simões Renata Duarte , Vieira Alexandro Braga
Published: December 2023

O artigo busca compreender os sentidos que têm sido atribuídos aos processos de avaliação da aprendizagem na educação infantil, a partir da análise de relatórios avaliativos de crianças matriculadas em três Centros Municipais de Educação Infantil, localizados em territórios periféricos da cidade de Vitória-ES. Fundamentando-se em autores, como Hoffmann (2012) e Godoi (2010), debate a avaliação da aprendizagem, refletindo como os relatórios avaliativos têm considerado os contextos sociais de vida de crianças empobrecidas. Recorre aos pressupostos da pesquisa-ação, sistematizados em um curso de extensão com profissionais da educação infantil. O curso possibilitou direcionar olhares para as práticas avaliativas classificatórias e excludentes. O estudo evidenciou uma educação voltada à escolarização das crianças a partir de modelos hegemônicos presentes também nas avaliações, que desconsideram as realidades sociais. Foi possível repensar com o coletivo práticas educativas-avaliativas que respeitem as subjetividades infantis em um movimento de defesa de uma educação pública e de qualidade efetivamente inclusiva.
Reaction–diffusion systems with nonlinear sources of different intensity
in the case of a multiple root without quasimonotonicity condition
Authors: Simakov R. E.
Published: December 2023

We consider a boundary value problem for a singularly perturbed system of two second-order ordinary
differential equations with different powers of a small parameter at the second derivatives without requiring the
right-hand sides to be quasimonotonic. The specific feature of the problem is that one of the two equations in
the degenerate system has a double root. It is proved that for sufficiently small values of a small parameter, the
problem has a solution of the boundary layer type. A condition is obtained that replaces the quasimonotonicity
condition and expands the class of problems to which the results of the work are applicable.
Mechanical alloying in compositions iron–titanium–carbon (diamond)
Authors: Kovaliova S.A. , Kiseleva T.Yu. , Grigoreva T.F. , Zhornik V.I. , Devyatkina E.T. , Vosmerikov S.V.
Published: December 2023

X-ray diffraction analysis, scanning electron microscopy and M¨ossbauer spectroscopy have been applied to the study of Fe-xTi (x=20–40 wt.%), Fe/xTi-diamond and Fe–Ti–C powders structure formation under the conditions of an AGO-2 planetary ball mill. It has been shown that metals with high melting points and limited solubility under high-energy mechanical action for 20 min interact to form an alloy of nanostructured iron and grain-boundary phases similar to solid solutions of Fe(Ti), Ti(Fe) and FeTi with a total content of 22–24 %. In the Fe-20wt.%Ti composition, titanium reaches an X-ray amorphous state, and when the titanium content is above 20 wt.% 𝛼-Ti crystalline phase remains in an amount of 5–10 wt.%. When the Fe/xTi-diamond mixture is mechanically activated, composite particles with a metal matrix structure with a diamond size of 0.3–1.5 𝜇m are formed. It has been established titanium accelerates the process of grain-boundary and volumetric interaction of iron with diamond and titanium carbide. In the powder compositions under study, a solid solution is formed based on iron and TiC, Fe3C compounds with their total content: Fe/40 wt.%Ti-diamond up to 62%; Fe/TiC up to 34%. Under similar conditions in a diamond-iron mixture, the grain-boundary phases of the solid solution do not exceed 26%. The formation of graphite has not detected by X-ray diffraction.
Latest Advances in Scanning Ion-Conductance Microscopy and Nanopipette
Systems for Single-Cell Analysis under Serial Conditions
Authors: Shergin D.A. , Yakovlev A.P , Gorelkin P.V. , Salikhov S.V. , Erofeev A.S.
Published: December 2023

Studying single cells opens opportunities for understanding many biological processes and, as a consequence,
plays an important role in the development of biomedicine. Scanning Ion Conductance Microscopy (SICM)
and nanopipette systems for the analysis of single cells represent a powerful tool for investigating the
morphological, mechanical, and biochemical features of living cells with nanometer spatial resolution under
near-natural conditions. Over the last decades, SICM has shown great success in studying and manipulating
single cells, and the non-contact nature of the system, combined with the unique features of nanopipettes
used as probes, has opened new possibilities for the application of such systems in biomedical applications.
This review reflects the latest trends and directions in the development of SICM and nanopipette systems for
the single-cell analysis.
Enhancing Technical Skills Using Under-Passing and Game Approach in Girls Volleyball
Authors: Khoirudin Dwi , Pratama Henri Gunawan , Santoso Danang Ari , Putro Baskoro Nugroho
Published: December 2023

Background: A long-term training process is required to train athletes, which requires systematic, targeted, planned, and repetitive handling. Training methods improve the mastery of fundamental techniques for beginner athletes. Training volleyball methods are essential for beginners as they make the exercise more focused and gradual to improve their under-passing. Coach training methods make it easier to give practical and concentrated exercises to the areas you want to enhance.
Objective: The study aims to determine whether drill exercise and game approach can significantly improve female athletes' use of under-passing volleyball.
Methods: With the type of research being Quasi-Experimental. The research design used was Randomized Control Group Pretest-Posttest Design. A total of 24 athletes were given treatment for two months. The instrument used was the Braddy Volleyball Test, and data analysis used the T-Test.
Results: Results for the drill exercise experimental group were 0.695 > 0.05, and for the experimental group, the playing method was 0.695 > 0.05. This means that drill exercises and game approaches significantly improve the skills of passing volleyball.
Conclusion: In experimental groups, I and II, athletes who were given a drill exercise program and game approach both improved their skills in the basic techniques of skills under-passing volleyball. The average posttest results of both groups of experiments are higher than the average pretest results. It shows a difference between the drill exercise program and the game approach.
RISCO DE PROCEDIMENTO ESTÉTICO COM ÁCIDO HIALURÔNICO – UMA REVISÃO DE LITERATURA
Authors: Alcântara Leonardo Ian , Welter Graciele Selma , Ferreira Jaqueline dos Santos , Chaves Karine Rodrigues do Nascimento
Published: December 2023

Os procedimentos estéticos com ácido hialurônico (AH) são amplamente adotados para melhorar a aparência facial e corrigir imperfeições. No entanto, apesar de sua popularidade crescente, esses procedimentos não estão isentos de riscos. Este artigo se propõe a revisar e analisar os principais riscos associados ao uso de ácido hialurônico em procedimentos estéticos, com base em uma revisão abrangente da literatura científica. A revisão identifica quatro principais riscos: Reações Alérgicas e Hipersensibilidade; Assimetria e Deslocamento do Preenchimento e Necrose Tecidual; Infecções. A compreensão desses riscos e sua mitigação por meio de práticas clínicas  aprimoradas são cruciais para garantir que os pacientes desfrutem dos benefícios estéticos do ácido hialurônico com segurança. Embora a maioria dos pacientes passe por esses procedimentos sem complicações significativas, a seleção criteriosa dos pacientes e a capacitação dos profissionais de saúde são fundamentais para minimizar esses riscos e garantir resultados estéticos satisfatórios e seguros. Este artigo visa fornecer uma visão abrangente dos desafios e oportunidades associados aos procedimentos estéticos com ácido hialurônico, contribuindo para uma prática clínica mais informada e segura.
Analysis of Wireless Networks: Successful and Failure Existing Technique
Authors: Chavan Pundalik , Ali Anooja , C Ramaprasad H , V Ramachandra H , H Hari Krishna , Satish E G
Published: December 2023

One special feature of wireless networks is their capacity to keep people in contact even when they switch locations. The adaptability and agility needed for wireless communications are provided. The fields of business, education, defense, home-based and industrial applications, and the military environment have all found use for wireless and mobile communications. The world has changed significantly as a result of wireless networks since they have made it easier, more reliable, and more efficient to send information abroad or behind enemy lines. An essential productivity tool for today's mobile workforce is wireless networking. With wireless networking, we may practically access corporate and other information resources at any time and from any location. In recent times, wireless networks have become more commonplace in several fields, such as satellite broadcasting, mobile analog, and digital cellular telephones. Supporting a good quality of service (QoS) in this environment for the delivery of voice, video, and data has therefore become one of the major challenges of the twenty-first century. In this research article, we provide an overview of wireless networks, their classification, and quality of service (QOS) parameters such as bandwidth, delay, delay variation (jitter), throughput, and energy. Lastly, we provide security information regarding various parameters for end-to-end communication over wireless networks.
Stress, overload and spiritual related to the quality of life of caregivers of older adults
Authors: Donjuan Díaz Berenice Elizabeth , Duran-Badillo Tirso , Guerra Ordoñez Jesús Alejandro , Ruiz Cerino Juana María
Published: December 2023

Introduction: the identification of risk and protective factors for quality of life allows the development of interventions to improve the quality of life of caregivers of older adults. Objective: determine the relationship between stress, overload and spirituality with the quality of life of caregivers of older adults. Methods: cross-sectional and analytical study in 97 caregivers of older adults. The Perceived Stress Scale, Zarit test, Spirituality Questionnaire and Whoqol Breff questionnaire were applied. Descriptive and inferential statistical tests were applied. Results: no statistical significance was observed of overload, stress and spirituality on global quality of life (F [3, 93] = 2,19, p = 0,094). Overload is a risk factor for physical quality of life (p=0,002), stress is a risk factor (p<0,001) and spirituality is a protective factor (p<0,001) for psychological quality of life, stress is a risk factor for social quality of life (p=0,023) and spirituality is a risk factor for environmental quality of life (p=0,002). Conclusions: the design of interventions to improve the quality of life of caregivers must consider addressing stress and overload since they are factors that affect the dimensions of quality of life. Spirituality is a protective factor for psychological and environmental quality of life, so it is important to encourage its practice in caregivers
Proniosomal gel mediated transdermal delivery of Donepezil HCl: Development and in vitro characterization
Authors: Sai Sreenidhi K  , Anand Kumar Yegnoor
Published: December 2023

The aim of this research was to study the potential of proniosomal gel for transdermal delivery. Donepezil HCl loaded proniosomal gels were prepared by the coacervation phase separation method using different nonionic surfactants (spans and tweens). The prepared Donepezil HCl proniosomal gels were evaluated for various parameters such as particle size (PS), drug entrapment efficiency percentage (EE %), and in vitro drug release. Donepezil HCl loaded proniosomal gel was prepared successfully by coacervation phase separation method. The prepared proniosomal gel exhibited desired entrapment efficiency and Particle size. It was found that B2 which chosen as a best formula according to entrapment efficiency, Particle size, and in vitro release study. It was found that B2 which contains high concentration of span 60 is the most appropriate surfactant for the preparation of proniosomes. In vitro release studies proved that the prepared proniosomal gel contains Donepezil HCl considered to be a successful topical transdermal drug delivery system and provide a sustained release of encapsulated drug. Furthermore, there was no significant change in EE % and PS of Donepezil HCl proniosomal gel after storage for 6 months.
Toxicity profile of metals in water, sediments and Liza grandisquamis from Iko River, South-South of Nigeria
Authors: Aniefiokmkpong Okokon Okon  , Godwin Asukwo Ebong  , Victoria Paul Tombere  , Idongesit Bassey Anweting  , Helen Solomon Etuk  , Idongesit Ambrose
Published: December 2023

Water pollution and the risks associated with the prolonged exposure to contaminated water source by human is becoming a serious problem globally. The concentrations, cancer and non-cancer risks of Cd, Cr, Ni, and Pb via exposure to water, fish, and sediments from Iko River were examined. Results obtained showed that, the mean concentrations of these metals in fish and sediments were within their recommended limits however; the levels in water were higher than their limits. Principal component analysis (PCA) indentified anthropogenic factor as the major source of all the toxic metals in the environmental media assessed. The estimated daily intake (EDI) rate of the metals revealed that, Cd in water and sediments for both the adult and children populations were higher than their recommended daily oral reference doses (Rfds). The EDI for Cr in all the samples and ages were within the Rfd. While the EDI of Ni in water and fish for both populations were within the Rfd limit, but it was higher in sediments for both populations. The EDI of Pb for all the samples and ages were higher than the Rfd. The hazard indices of these metals were higher than one in water and sediments but less than one in fish for both populations. However, the children class was more susceptible to the non-carcinogenic risks. The results obtained also showed that, Cd and Pb were the major contributors to the reported non-carcinogenic risks. The total cancer risks (TCR) of the metals in all the samples and ages were higher than the recommended limit and the risks were higher in the children than the adult’s class.
Study on the influence of roof load combination on deformation control of shallow buried tunnel section
Authors: Zhang Lin
Published: December 2023

The shallow buried section of a tunnel exit in Kangding transit section of Kangxin Expressway in Sichuan Province is affected by the combination of loads on the roof of the tunnel, resulting in deformation phenomenon, which affects the safety and stability of tunnel construction. Based on the theory of elastic-plastic mechanics, combined with finite element numerical simulation, the article analyzes the stress distribution characteristics, plastic zone development and deformation characteristics of the surrounding rock of this tunnel section under different load combinations, exposes the influence of load combinations on the deformation of the tunnel, and puts forward a solution for the deformation of the surrounding rock in the course of this tunnel construction. The results show that the stress at the foot of the tunnel is more concentrated in the early stage of tunnel excavation, and the stress at the foot of the tunnel produces a maximum value of stress, which gradually decreases from the foot of the arch to the top of the arch. The load combination has no significant effect on the stress concentration areas, but will significantly increase the stress values at the foot of the arch. After excavation, the plastic zone of peripheral rock appears at the location of the side wall. With the construction of the primary support, the primary support bears the lateral pressure of the peripheral rock and transmits the pressure of the peripheral rock to the foot of the tunnel primary support, and the plastic zone is then transferred to the peripheral rock at the bottom of the foot of the primary support. The greatest deformation of the tunnel surrounding rock occurs at the roof or bottom of the tunnel, and the amount of displacement increases continuously with the increase of load. For the deformation characteristics of the tunnel surrounding rock after tunnel excavation and after various types of loads are applied during the construction process, the deformation control measures to be taken under each working condition are proposed, and these measures have a positive effect on the stability of the tunnel structure.
MENILAI KEEFEKTIFAN PROGRAM PEMBERDAYAAN KELOMPOK WANITA NELAYAN DALAM PENINGKATAN KEMAMPUAN DAN PEREKONOMIAN MASYARAKAT: STUDI KASUS PROGRAM HOLISTIK PEMBINAAN DAN PEMBERDAYAAN DESA (PHP2D) DI KELOMPOK NELAYAN KAMPUNG BAJO KELURAHAN ANAIWOI, KABUPATEN KOLAKA, SULAWESI TENGGARA
Authors: Prihantini Campina Illa , Soleha Dini , Syahrir
Published: December 2023

Penelitian ini bertujuan untuk menganalisis dampak yang dirasakan masyarakat setelah mengikuti kegiatan pengabdian Program Hibah Pengabdian dan Pemberdayaan Desa (PHP2D). Analisis yang digunakan adalah analisis persepsi masyarakat penerima program terhadap tingkat pemahaman, tingkat kemampuan atau skill, dan tingkat pendapatan setelah program berakhir. Responden adalah msyarakat penerima program sehingga metode penentuan responden adalah Purposive Sampling Method yang berjumlah 30 orang. Hasil analisis persepsi dengan menggunakan skala likert menunjukkan bahwa tingkat pemahaman masarakat sudah paham terhadap apa yang telah disampaikan di kegiatan program yang persentasi nilainya 60 % responden paham, untuk tingkat kemampuan atau skill masyarakat sudah sangat berubah yang persentasinya 70% responden sangat paham sedangkan untuk tingkat pendapatan masyarakat masih kategori tetap yang dimana nilai persentase 86,66% responden menyatakan belum adanya perubahan pendapatan dari program tersebut.
PERAN EKONOMI KREATIF DALAM MENINGKATKAN PENDAPATAN LEMBAGA PERS MAHASISWA INKADHA SUMENEP DITINJAU DARI BISNIS ISLAM
Authors: Utami Kristiani
Published: December 2023

Jurnal Penelitian dengan judul “Peran Ekonomi Kreatif dalam Meningkatkan Pendapatan Lembaga Pers Mahasiswa Inkadha Sumenep Ditinjau dari Bisnis Islam” Dalam pandangan ekonomi islam Mengenai pendapatan yang diperolah dari hasil usaha dokumentasi. Teknik analisis data yang digunakan yaitu menurut Miles dan Huberman, meliputi: reduksi data, penyajian data serta penarikan kesimpulan dan verifikasi. Sedangkan dengan teknik pengecekan keabsahan data yang digunakan dalam jurnal penelitian ini dilakukan dengan, perpanjangan pengamatan, peningkatan ketekunan dalam penelitian, triangulasi, hingga diskusi dengan teman sejawat. Hasil dalam penelitian ini, yiatu: 1) Mahasiswa anggota LPM (Lembaga Pers Mahasiswa) yang terlibat secara langsung dalam bisnis yang di tekuni saat ini sangat berdampak baik bagi  peningakatan pendapatan yang membuat taraf hidup atau perekonomian mereka semakin. 2) Yang kedua yaitu secara tidak langsung menambah pengalaman dan wawasan kerja bagi para mahasiswa anggota Pers inkadha sumenep. 3) Sehubungan dengan penelitian ini, kinerja atau pelayanan kepada konsumen yang di berikan oleh karyawan atau mahasiswa anggota Pers tersebut sudah memenuhi kaidah atau perspektif dalam bisnis islam. Bisnis yang menghasilkan manfaat dan tidak dilarang oleh agama, dari berbagai tahapan yang baik sehingga hasil atau upah yang di dapat dari bisnis tersebut di nyatakan sah atau halal dan tidak menjadi masalah.
GENOTYPIC AND PHENOTYPIC COMPARISON OF DRUG RESISTANCE PROFILES OF M. tuberculosis ISOLATES
Authors:   Republican TB Dispensary, Yoshkar-Ola, Russia, Petrova L.V. , Sevastyanova E.V. ,   Central TB Research Institute, Moscow, Russia, Larionova E.E. ,   Central TB Research Institute, Moscow, Russia, Smirnova T.G. ,   Central TB Research Institute, Moscow, Russia
Published: December 2023

We conducted a comparative analysis of drug resistance of M. tuberculosis isolates to first-line TB drugs. The diagnostic samples and cultures of M. tuberculosis from TB patients were tested in the Mari El Republic. It was established that the divergence between genotypic and phenotypic isoniazid resistance did not exceed 4%, and rifampicin resistance – 3.9%. In most cases there was lack of mutations associated with resistance to isoniazid or rifampicin in the presence of phenotypic resistance. However, the divergence between results obtained by genotypic and different phenotypic methods was not only seen for M. tuberculosis isolates genotypically referred to sensitive, but also for M. tuberculosis isolates genotypically referred to resistant.