bluuebunny/crossref_metadata_2025 huggingface dataset:
Electrochemical Analysis of Narcotic Drugs Using Nanomaterials Modified
Electrodes – A Review
Authors: Nagarajan Ramila Devi , Kavitha J. , Atchudan Raji , Arya Sandeep , Sundramoorthy Ashok K.
Published: June 2023

The usage of abused illicit drugs remains an increasing challenge for drug regulatory authorities
and therefore, it is important to develop advanced sensor technology that able to identify and determine
drugs concentration in seized samples, biological fluids and food samples. The World Health Organization
(WHO) recommends the usage of narcotic drugs legally for the medical treatments. Thus, many
reports indicated that the higher dosage level led to drug addiction and mental disorders in humans. The
United States record showed about 0.46 million cases of deaths due to the overdose of opioids-related
drugs every year. This review discusses the electrochemical analysis (DPV, CV, EIS spectra, etc.) of various
narcotic drugs using electrochemical transducers made of nanomaterials such as gold nanoparticles,
single-walled carbon nanotubes, Zn2SnO4/graphene nanocomposite, cysteamine functionalized gold nanoparticle
conjugated with an aptamer, etc. There were many challenges reported during the electroanalysis
of narcotic drugs. Some of the wearable devices were also made for the sensing of narcotic
drugs. Specifically, electro-analysis of nicotine, morphine, codeine and cathonine using 2D nanomaterials
and their nanocomposites-based electrochemical sensors fabricated on flexible substrates were discussed.
In particular, the linear range of detection, limit of detection (LOD), interference and real-world sample
analysis were highlighted. It was concluded that wearable sensors could be used for the monitoring of
illicit drugs and their derivatives in day-to-day life.
Naturally Occurring Herbs and their Bioactive Metabolites: Potential Targets and Signaling Pathways of Antiviral Agents
Authors: Singh Sonia , Sharma Shiwangi , Sharma Himanshu
Published: June 2023

Viruses significantly impact global health because they are the leading cause of death everywhere they are found. Despite the rapid development of human healthcare, more effective viricidal or antiviral therapies must be developed. The need to find safe, novel, and effective alter-natives against viral diseases is heightened by the rapid emergence of resistance to, and the high cost of, synthetic antiviral drug(s). The development of novel multi-target antiviral compounds that affect multiple steps of the viral life cycle and host proteins has benefited tremendously from look-ing to nature for guidance and inspiration. Hundreds of natural molecules are preferred over syn-thetic drugs because of concerns regarding efficacy and safety and a high resistance rate to con-ventional therapies. In addition, naturally occurring antiviral agents have demonstrated reasonable antiviral value in both animal and human studies. Therefore, finding new antiviral drugs is crucial, and natural products provide an excellent opportunity. This brief review examines the evidence of antiviral effects exhibited by various plants and herbs.
The Impact of Counseling on the Dignity of Older People: Protocol for a Mixed Methods Study (Preprint)
Authors: Hung Ho Yeow , Azman Azlinda , Jamir Singh Paramjit Singh
Published: June 2023

BACKGROUND

Psychological counseling is perceived as a treatment that could significantly improve older individuals’ psychological and behavioral functioning. There is a dearth of information on the impact of psychological counseling on preserving dignity and facilitating good aging among older people in Singapore.

OBJECTIVE

The objectives of this study are as follows: (1) to assess advance care planning among older people and their perception of life and health, end of life, and end-of-life care; (2) to explore older people’s accessibility and receptiveness toward counseling; (3) elucidate older people’s perspectives on counseling and its impact on emotional management and decision-making; (4) to assess older people’s competencies in emotional management; and (5) to propose an intervention model for enhancing older people’s well-being and dignity through psychological counseling in Singapore.

METHODS

A mixed method study design involving quantitative and qualitative methods will be used. Older individuals receiving some form of preventive, primary, or long-term care in the community through voluntary welfare organizations from the senior activity centers located in eastern Singapore participated in the qualitative phase. Six older individuals from each senior activity center have been enrolled for the interview phase to explore 6 components: the Advanced Care Planning (ACP) booklet, Trait Meta Mood Scale (TMMS), accessibility and receptiveness toward counseling, and emotional management and decision-making. The ACP, an instrument designed to assess advanced care planning among older individuals, and the TMMS, an instrument developed to measure meta-mood experience and emotional management, were used in the quantitative phase among 100 participants. The data will be analyzed thematically using NVivo version 12, whereas descriptive statistics and a 2-tailed, 1-sample t test will be conducted in SPSS (version 25; IBM Corp) for empirical data analyses.

RESULTS

The qualitative phase, which involves a semistructured interview, has been completed among 20 older individuals aged 66-86 years. Thematic analysis of the data is still ongoing. Meanwhile, the quantitative phase commenced on March 22, 2022, with 100 participants providing signed informed consent to participate in the study. The study is expected to be completed by March 2023.

CONCLUSIONS

The mixed methods study will document the current awareness of ACP, accessibility and receptiveness toward counseling, and the potential use of psychological counseling in enhancing well-being and dignity among older people in Singapore. The research findings will benefit policy makers in their decision-making when attempting to mitigate the potential barriers to seeking counseling assistance among older people.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/45557
The Effects of Exercise on Synaptic Plasticity in Individuals With Mild Cognitive Impairment: Protocol for a Pilot Intervention Study (Preprint)
Authors: Ramdeo Karishma R , Fahnestock Margaret , Gibala Martin , Selvaganapathy Ponnambalam Ravi , Lee Justin , Nelson Aimee Jennifer
Published: June 2023

BACKGROUND

Mild cognitive impairment (MCI) is a syndrome preceding more severe impairment characterized by dementia. MCI affects an estimated 15% to 20% of people older than 65 years. Nonpharmacological interventions including exercise are recommended as part of overall MCI management based on the positive effects of exercise on cognitive performance. Interval training involves brief intermittent bouts of exercise interspersed with short recovery periods. This type of exercise promotes cognitive improvement and can be performed in individuals with MCI. Synaptic plasticity can be assessed in vivo by the neurophysiological response to repetitive transcranial magnetic stimulation (rTMS). A method to assess synaptic plasticity uses an intermittent theta burst stimulation (iTBS), which is a patterned form of rTMS. Individuals with MCI have decreased responses to iTBS, reflecting reduced synaptic plasticity. It is unknown whether interval training causes changes in synaptic plasticity in individuals living with MCI.

OBJECTIVE

This research will determine whether interval training performed using a cycle ergometer enhances synaptic plasticity in individuals with MCI. The three aims are to (1) quantify synaptic plasticity after interval training performed at a self-determined intensity in individuals with MCI; (2) determine whether changes in synaptic plasticity correlate with changes in serum brain-derived neurotrophic factor, osteocalcin, and cognition; and (3) assess participant compliance to the exercise schedule.

METHODS

24 individuals diagnosed with MCI will be recruited for assignment to 1 of the 2 equally sized groups: exercise and no exercise. The exercise group will perform exercise 3 times per week for 4 weeks. Synaptic plasticity will be measured before and following the 4-week intervention. At these time points, synaptic plasticity will be measured as the response to single-pulse TMS, reflected as the percent change in the average amplitude of 20 motor-evoked potentials before and after an iTBS rTMS protocol, which is used to induce synaptic plasticity. In addition, individuals will complete a battery of cognitive assessments and provide a blood sample from the antecubital vein to determine serum brain-derived neurotrophic factor and osteocalcin.

RESULTS

The study began in September 2023.

CONCLUSIONS

The proposed research is the first to assess whether synaptic plasticity is enhanced after exercise training in individuals with MCI. If exercise does indeed modify synaptic plasticity, this will create a new avenue by which we can study and manipulate neural plasticity in these individuals.

CLINICALTRIAL

ClinicalTrials.gov NCT05663918; https://clinicaltrials.gov/study/NCT05663918

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/50030
Enhancing Energy Efficiency in Telehealth Internet of Things Systems Through Fog and Cloud Computing Integration: Simulation Study (Preprint)
Authors: Guo Yunyong , Ganti Sudhakar , Wu Yi
Published: June 2023

BACKGROUND

The increasing adoption of telehealth Internet of Things (IoT) devices in health care informatics has led to concerns about energy use and data processing efficiency.

OBJECTIVE

This paper introduces an innovative model that integrates telehealth IoT devices with a fog and cloud computing–based platform, aiming to enhance energy efficiency in telehealth IoT systems.

METHODS

The proposed model incorporates adaptive energy-saving strategies, localized fog nodes, and a hybrid cloud infrastructure. Simulation analyses were conducted to assess the model’s effectiveness in reducing energy consumption and enhancing data processing efficiency.

RESULTS

Simulation results demonstrated significant energy savings, with a 2% reduction in energy consumption achieved through adaptive energy-saving strategies. The sample size for the simulation was 10-40, providing statistical robustness to the findings.

CONCLUSIONS

The proposed model successfully addresses energy and data processing challenges in telehealth IoT scenarios. By integrating fog computing for local processing and a hybrid cloud infrastructure, substantial energy savings are achieved. Ongoing research will focus on refining the energy conservation model and exploring additional functional enhancements for broader applicability in health care and industrial contexts.
Asynchronous versus synchronous screening for depression and suicidality: A quality improvement study in a primary care health system (Preprint)
Authors: Sattler Amelia , Dunn Julia , Albarran Marleni , Berger Charlotte , Calugar Ana , Carper John , Chirravuri Lalitha , Jawad Nadine , Zein Mira , McGovern Mark
Published: June 2023

BACKGROUND

Despite being a debilitating, costly, and potentially life-threatening condition, depression is often underdiagnosed and undertreated. Pre-visit Patient Health Questionnaire–9s (PHQ-9) may help primary care health systems identify symptoms of severe depression and prevent suicide through early intervention. Little is known about the impact of pre-visit web-based PHQ-9s on patient care and safety.

OBJECTIVE

Investigate differences among patient characteristics and provider clinical responses for patients who complete a web-based (asynchronous) versus in-clinic (synchronous) PHQ-9.

METHODS

This quality improvement study was conducted at 33 clinic sites across two health systems in Northern California from November 1, 2020 to May 31, 2021 and evaluated 1,683 (0.9% of total PHQs completed) records of patients endorsing thoughts that they would be better off dead or of self-harm (Q#9) following implementation of a depression screening program that included automated electronic pre-visit PHQ-9 distribution. Patient demographics and providers’ clinical response (suicide risk assessment, triage nurse connection, medication management, electronic consultation with psychiatrist, referral to social worker or psychiatrist) were compared for patients with asynchronous versus synchronous PHQ-9 completion.

RESULTS

Of the 1,683 patients (63.7% female, 80.5% non-Hispanic, and 51.6% White), Hispanic and Latino patients were 40% less likely to complete a PHQ-9 asynchronously (OR=0.6; 95% CI: 0.45-0.8; p<0.001). Patients with Medicare insurance were 36% (OR=0.64; 95% CI: 0.51-0.79) less likely to complete a PHQ-9 asynchronously than patients with private insurance. Those with moderate to severe depression were 1.61 times more likely (95% CI: 1.21-2.15; p=0.001) to complete a PHQ-9 asynchronously than those with no or mild symptoms. Patients who completed a PHQ-9 asynchronously were twice as likely to complete a Columbia-Suicide Severity Rating Scale (OR=2.41; 95% CI: 1.89-3.06; p<0.001) and 77% less likely to receive a referral to psychiatry (OR=0.23; 95% CI: 0.16-0.34; p<0.001). Those who endorsed Q#9 “more than half the days” (OR=1.62; 95% CI: 1.06-2.48) and “nearly every day” (OR=2.38; 95% CI: 1.38-4.12) were more likely to receive a referral to psychiatry than those who endorsed Q#9 “several days” (p=0.002).

CONCLUSIONS

Shifting depression screening from in-clinic to pre-visit led to a dramatic increase in PHQ-9 completion without sacrificing patient safety. Asynchronous PHQ-9s can decrease workload on frontline clinical team members, increase patient self-reporting, and elicit more intentional clinical responses from providers. Observed disparities will inform future improvement efforts.

CLINICALTRIAL
Nghiên cứu chất lượng nước và tải lượng đạm và lân của ao nuôi thâm canh cá lóc đầu nhím (Channa sp.) ở huyện Tam Nông tỉnh Đồng Tháp
Authors: Lê Diễm Kiều , Phạm Quốc Nguyên
Published: June 2023

Nghiên cứu chất lượng môi trường nước của ao nuôi thâm canh cá lóc đầu nhím (Channa sp.) được thực hiện ở huyện Tam Nông tỉnh Đồng Tháp. Mẫu nước đầu vào, trong ao nuôi và nước thải của ao nuôi cá lóc được thu vào thời điểm 45, 95 và 135 ngày sau khi thả cá. Kết quả cho thấy nước cấp cho ao nuôi cá lóc được khảo sát hầu hết đều đạt QCVN:08-MT/2015/BTNMT (cột A1). pH và DO của nước ao nuôi và nước thải có khuynh hướng giảm, trong khi EC và TDS đều tăng. Nồng độ đạm vô cơ và lân của ao nuôi đều tăng so với nước cấp nhưng hầu hết vẫn trong giới hạn thích hợp cho cá lóc sinh trưởng và phát triển. Nồng độ N-NH4+, N-NO2- và P-PO43- của nước thải đều cao hơn so với nước cấp (p<0,05) và đều vượt QCVN:08-MT/2015/BTNMT cột B2.Tải lượng N-NH4+, N-NO2-, N-NO3-, P-PO43- và TP trong nước thải ao nuôi thâm canh cá lóc sau 5-6 tháng lần lượt là 154,17; 22,47; 58,95; 62,02 và 99,20 kg/1000 m2/vụ,vì vậy cần có giải pháp theo dõi và xử lý nước thải của ao nuôi cá lóc trước khi thải ra môi trường nhằm bảo vệ môi trường và phát triển bền vững mô hình nuôi loài thủy sản này.
Comparison Analysis of the Strength of Cement Bricks and Sago Bricks
Authors: Nanlohy Ansye , Redolf Vector Reinhard , Lewakabessy Hutubessy. Godfried , Soumokil Musper
Published: June 2023

Objective from study This For know how much big strong press on the brick sago that can become material addition as one _ alternative material building. Pith sago only end become waste on site processing sago in a manner tradition in Maluku Province. Study about utilization pith sago Already done However Not yet can utilized as product brick . Study This use print measuring 290 x 120 x 80mm. Composition Concrete brick sago sand 53%, cement 25%, pith sago 6%, water 16%, for cement brick test object on the market For tested the comparison . Heavy average cement brick 5297.90 gr and sago brick of 3602.54 gr with percentage weight 31.97% more light . Strong test results press Concrete brick cement obtained respectively 3.4 MPa, 2.4 MPa, 5.9 MPa. Concrete brick sago produce strong press respectively 20.5 MPa, 21.3 MPa, 24.1 MPa with strong average press of 22 MPa, so up to comparison strong very significant press . B atako sago produce strong press more _ tall from cement brick with percentage _ strong press to Concrete brick sago of 82.25%. Percentage elasticity Concrete brick sago to cement brick by 58.60%. Concrete brick sago own strength more compressive and elasticity _ big from cement bricks up to can used as one _ material building specifically for non- structural Because characteristic ductile
Data 4 Climate Action Edinburgh
Authors: Ward Pauline
Published: June 2023

Data 4 Climate Action Edinburgh is a group of volunteers, donating our time and skills with data to support climate action and biodiversity in and around Edinburgh.
The formation of the group was the idea of Pauline Ward, inspired on hearing discussions about the how climate action groups could be supported, and how they could help each other, through regional networks. Discussions with the Edinburgh Voluntary Organisations Council and the Scottish Secretariat for Climate Action Networks identified a role for D4CAE as part of such a network in Edinburgh. The Scottish Government has been working on a programme of support for such regional networks, the first being North East Scotland Climate Action Network. Specifically, there appeared to be great potential in facilitating the making of connections between local climate groups and prospective volunteers from among the staff and students of the University of Edinburgh. With practical support and dialogue with the University of Edinburgh Sustainability team and Community Engagement team, D4CAE carried out a survey of members of the public at the Edinburgh Climate Festival 2022. Underneath the University gazebo, individuals volunteered to help and talked with us about what areas of work would be most worthwhile in their view. The participants indicated their choices by placing chips into paper cups labelled with the options ‘mapping’, ‘sharing’ etc. The top result was ‘storytelling with data’. Volunteers asked us to create a mailing list so they could keep in touch and help. Climate activists told us they wanted help with presenting data about their activities for inclusion in funding bids, and mapping.
We now have a facebook page, website and a github repository. We use free tools from Google for email and file sharing (Drive, Sheets, Docs). We hold a monthly online drop-in on Zoom. We’re working on building links into the university, and working with data.
Biggest challenges – Many of our contacts who want to help are doing so in a professional capacity, and therefore mostly available during office hours, while the volunteer effort happens outside of working hours. Meanwhile, making the local groups aware of our offer is an area we need to work on, in partnership with the climate action network which is evolving and taking shape.
Looking ahead – hoping to organise a datathon event near or at the university in the near future.
Delivering skills – we’re in the business of sharing skills, and building our own skills with data along the way. We have fielded requests for help with non-climate data, both from professional life science researchers looking for help with data visualisation, and others through the community engagement network. The experience suggests there may be potential for a platform and other work to build more links for voluntary organisations to find help with specialised skills among the staff and students of the university.
Applying Intelligent Open Science to Combat Future Pandemics
Authors: Loffreda Lucia , Cox Eleanor , Johnson Rob
Published: June 2023

The COVID-19 pandemic demonstrated the potential strengths and existing weaknesses of open science practices and open data sharing to addressing urgent social and technological challenges. It was a time when pathogen genomic data was shared worldwide to characterise virus outbreaks, track the mutation and spread of the virus, and develop public health responses. However, this brought a renewed focus to the practice, incentives and infrastructures that crucially enable data sharing and reuse.
In 2022, the Department for Business, Energy and Industrial Strategy commissioned Research Consulting to investigate the opportunities and challenges associated with open data sharing during the pandemic. This work follows a commitment made during the UK’S G7 Presidency, as published in the G7 Research Compact, and its findings are closely aligned to those outlined in the World Health Organization’s recently published guiding principles for pathogen genome data sharing.
Our talk draws on evidence base of 295 sources, the views of 24 interviewees, and insights from 18 international peer reviewers to present five key lessons that can be learnt to enable preparedness for future pandemics.
Making Research FAIR With a PID-centric Workflow
Authors: Chen Xiaoli
Published: June 2023

Persistent identifiers (PIDs) are unique, machine-readable codes assigned to research entities that allow them to be easily discoverable. PIDs, along with their accompanying metadata, are crucial enablers of the FAIR principles (Findable, Accessible, Interoperable, and Reusable). PIDs ensure that digital objects can be located, accessed, and reused by humans and machines alike, while metadata provides essential information about research objects, including their origin, content, and format.
In the research ecosystem, each stakeholder has a role to play in integrating PIDs into their workflows. Publishers, for example, can assign DOIs (Digital Object Identifiers) to articles, books, and other publications, making them easily findable and citable. Repositories can assign PIDs to datasets, making them discoverable and accessible. Researchers can use PIDs to link their data to their publications, ensuring that their data is discoverable and can be reused in future research.
Despite the importance of PIDs and metadata, it's not always clear to researchers how to take advantage of the existing infrastructure and make their outputs FAIR. Being aware of the available PIDs, such as DOIs, ORCIDs, and RORs, and how they can be used to identify, connect, and cite various types of outputs and resources can help researchers plan and execute sensible data management, sharing, and publishing decisions that are efficient and beneficial in the long term.
In the Implementing FAIR Workflows Project, DataCite works with a team of researchers at the Max Planck Institute for Empirical Aesthetics to follow along a neuroscience PhD project from the beginning, to design and plan for a series of workflows that put the FAIR principles into practice, so that they become an inherent part of the research process, instead of an afterthought.  The FAIR workflows researcher is undertaking in the project include data management planning, experiment preregistration, domain-specific metadata capturing and archiving, data and code sharing, preprinting, and open access publishing. We have also been tracking the time spent on various types of FAIR and Open activities, hoping to shed a light on the actual time commitment expected for a FAIRly conducted research project.
We share our experience so far implementing these workflows with the Edinburgh Open Science community - the approach we used, the steps we’ve taken, and the outcomes and challenges that surfaced during the process. We are also preparing a guide for researchers to take on FAIR research workflows in their day-to-day work based on the lessons learned in the project, we look forward to taking the opportunity to hear from the community whether it resonates, and how can we format it in a way that’s most useful.
Open Science in the Wild
Authors: Wallis Kirsty
Published: June 2023

This talk uses real-world case studies to explore where and how open research can address global challenges and make a difference in the lives of everyday people worldwide. We explore these challenges through the work of UCL’s Office for Open Science and Scholarship and discuss how it is approaching support for similar projects and the expansion of the institution’s achievements in Open Science across the board.
Creating a University Wide Resource for Study Design Open Science and Data Analysis
Authors: Jordan Crispin
Published: June 2023

Join Crispin Jordan for his lightning talk, where he presents the new (and exciting) proposal for a broad scope, University wide centralised resource for training and best practice in study design, analysis and Open Science for disciplines across the University of Edinburgh.
South African Open Access and Open Data
Authors: Salematsela Daisy , Matizirofa Lazarus
Published: June 2023

Join our keynotes Daisy Salematsela (Director, WITS Libraries, Johannesburg, South Africa) & Lazarus Matizirofa (University of Pretoria) as they give us a survey of the progress being made in South Africa towards Open Access, Open Data, and Open Research in general - focusing on the role of the Library in this drive towards openness.
Rapid Aid – Android Application for Emergency Services
Authors: Vyas Yash
Published: June 2023

Abstract: At an alarming hour of emergency, we have seen that a lot of lives are at risk and many die due to improper planning and execution. So we have made an application which will be accessed to all the common citizens also would help the vehicle drivers who are working in emergency services, from various segments like Police vehicles, Ambulances also Fire Brigades at the time of emergency to reach the destination as soon as possible and execute their plan of action. It will also include all the necessary information from all the emergency-related departments of India. The application made is using android java and can be accessed by almost 95% of devices in the entire world. The prototypes of the UI and UX for our system are made via Adobe XD. Furthermore entering inside the application the login system is made using the Firebase technology which is fast being cloud based. We get an e-mail as soon as we insert our email to sign up as a user else we can access the app data being the guest user.
An Exploratory Study of the Influence of the Covid 19 Pandemic on EWS Students
Authors: Chauhan Ritika
Published: June 2023

Abstract: The COVID-19 crisis has forced education systems worldwide to find alternatives to face-to-face instruction. As a result, online teaching and learning have been used by teachers and students on an unprecedented scale. Since lockdowns – either massive or localized - may be needed again in the future to respond to new waves of the infection until a vaccine becomes available, it is of utmost importance for governments to identify which policies can maximize the effectiveness of online learning. This policy brief examines the role of students' attitudes towards learning in maximizing the potential of online schooling when regular face-to-face instruction cannot take place. Since parents and teachers play a fundamental role in supporting students to develop these crucial attitudes, particularly in the current situation, targeted policy interventions should be designed to reduce the burden on parents and help teachers and schools make the most of digital learning
Role of Information and Communication Technology (ICT) in Education
Authors: Yousuf Farhana
Published: June 2023

Abstract: With the development of scientific and technological innovations has effected every aspect of human life and field of education is one among them. ICT is providing different platforms for learners as well as educators in order to receive and share knowledge. These platforms are accessed by the learner’s community so to pursue their education. Educational Technology offers cost effective ways to reach to learners and access their understanding in various ways.ICT tools have been widely used by learners and educators in COVID times as it compelled them to shift to online education. It has changed the notion of physical classrooms as education was propagating in time and space less dimensions. The paper will analyse the use of Information and Communication Technology by learners in order to achieve their goals in relation to education.
FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUTUSAN PEGAWAI FEB UIN SYARIF HIDAYATULLAH, JAKARTA DALAM MEMBAYAR ZAKAT PROFESI
Authors: Ichsan Nurul , Rahmat Indra Nur
Published: June 2023

Penelitian ini bertujuan menganalisis faktor-faktor yang mempengaruhi keputusan Pegawai di Fakultas Ekonomi dan Bisnis dalam melaksanakan zakat profesi. Adapun faktor-faktor yang diteliti yaitu religiusitas, altruisme, motivasi, pengetahuan dan fintech. Data yang digunakan dalam penelitian ini data primer yang didapat dari kuesioner dan wawancara. Metode yang digunakan yaitu partial least square (PLS). Populasi dari penelitian ini adalah seluruh pegawai fakultas Ekonomi UIN Syarif Hidayatullah Jakarta sebanyak 183 responden, yang terdiri dari pegawai administrasi 35 orang, dosen tetap 98 orang, dosen tidak tetap 50 orang. Penentuan sampel mengacu pada rumus Slovin yakni 72 responden, teknik pengambilan sampel ini menggunakan probability sampling. Hasil penelitian ini menunjukan bahwa variabel religiusitas, altruisme, motivasi, pengetahuan dan fintech berpengaruh terhadap keputusan berzakat pegawai di Fakultas Ekonomi dan Bisnis UIN Syarif Hidayatullah Jakarta. Nilai R-square Adjusted sebesar  0,894%. Artinya bahwa variabel  religiusitas, altruisme, motivasi, pengetahuan dan fintech mempengaruhi keputusan dalam berzakat Profesi sebesar 89%, sedangkan 11% sisanya dipengaruhi oleh variabel lain di luar model yang di teliti. Implikasi dari penelitian adalah penelitian ini dapat digunakan sebagai referensi dalam perbandingan objek penelitian yang sama khususnya  tentang analisis faktor-faktor yang mempengaruhi keputusan dalam membayar zakat, selain itu untuk lembaga amil zakat penelitian ini diharapkan bisa menjadi acuan  untuk lebih memahami perilaku masyarakat dalam keputusannya membayar zakat sehingga bisa meningkatkan kinerja lembaga zakat dalam mengumpulkan dana.
Menulusuri Aspek Maritim Sungai Musi Untuk Pembelajaran Sejarah Lokal
Authors: Novemy Dhita Aulia , Reza Pahlevi Muhammad
Published: June 2023

The Musi River has an important role in historical periodization in Palembang, especially during the Srivijaya period. However, the role of the Musi river has not been conveyed so often in the concept of learning local history and its relation to maritime affairs. Based on these conditions, this study aims to examine the maritime aspects of the Musi River as a means of learning local history. The method used is a qualitative method using a historical approach. The role of the Musi river in Indonesian maritime needs to be developed for learning local history. This is very important because Sriwijaya's maritime glory was also influenced by the Musi river. This role can be explained through maritime aspects, namely trade, shipping, shipping, maritime traditions, sea mythology, piracy, fisheries, law of the sea. Based on exploring these maritime aspects, the material on the Musi river becomes broader and contextual to be applied in learning local history based on the basic competencies of the curriculum.
The Mathematical Literation Skill of Indonesian Elementary School Student
Authors: Indriani Ari , Novianti Dwi Erna
Published: June 2023

This study aimed to know the mathematical literation skill of elementary student. This study was qualitative descriptive approach. This study was held in SD Negeri 3 Kunduran. The population of this study was 5th grade with 39 students. The sampling was used saturation sampling technique. The data was collected using obervation, essay test, and documentation. Before the essay test was used, it was analyzed its content validity, level of difficulty, discrimination power, and reliability. Test was consist of 4 questions. The data technique was qualitative analysis with Miles and Hubermen model. This research showed that students who can worked on level 4 question were students who answered more correctly on question number 2. Students who can worked on level 3 question were students who answer more correctly on question number 4.This study concluded that the mathematical literation skill of 5th grade student in SD Negeri 3 Kunduran was good.
The Impact of Dynamic Shocks and Special Days on Time Series Data
Authors: HAFIZOĞLU GÖKDAĞ Zehra , BİLGE Ayşe Hümeyra
Published: June 2023

This paper includes an examination of a 4-year time series data on retail delivery demand generated by a logistics company based on the dates of creation. The periodic fluctuations observed in the data's normal structure are caused by the accumulation of demands over the weekend and their fulfillment at the beginning of the week. The aim of the study is modelling the response to unexpected changes in demand, which we refer to as "shocks," similar to the weekend effect. Special days, including single-day public holidays, religious holidays, and campaign periods in November, which represent specific periods, were also analyzed to interpret the patterns during these periods. The patterns created by single-day public holidays and religious holidays are significantly influenced by whether these days fall on a weekend or a weekday. By excluding weeks with special days from the overall data, the presence of shock effects in the remaining ordinary weeks was examined. During this period, the shock caused by the Covid-19 pandemic and adverse weather conditions was observed. The impact of the Covid-19 shock lasted longer compared to other shocks. When the increase in demand due to shocks exceeds the capacity of existing vehicles, the problem can be resolved by arranging daily rental vehicles from companies that provide vehicle allocations. Extracting the demand model for special days and unexpected shocks will ensure operational preparedness and prevent process delays. When ordinary weeks were examined, a monotonically decreasing trend from Monday to Sunday was observed based on the weekly average demand. The maximum demand was 58.3% on Monday, 17.2% on Tuesday, 15.9% on Wednesday, 7.3% on Thursday and 1.3% on Friday. The provided graphs also demonstrate a significant increase in demands in early 2020 due to the widespread adoption of e-commerce as a result of the Covid-19 pandemic
“REAÇÃO NOBEL NA ORGEXP2”: DEMONSTRAÇÃO DE UMA REAÇÃO CLICK CHEMISTRY NO LABORATÓRIO DE QUÍMICA ORGÂNICA EXPERIMENTAL 2
Authors: Barros José C. , De Oliveira Pereira Ana Carolina , Siqueira dos Santos Gabriel , Jacomo Jaques Silva Thamires , De Oliveira Costa Felisberto Vinicius , Lima da Silva Tiago , Da Silva Lima Camilo Henrique
Published: June 2023

O Prêmio Nobel de Química 2022 laureou Bertozzi, Meldal e Sharpless pelo desenvolvimento da Click Chemistry e da Química Bioortogonal. O tema deste Prêmio por sua simplicidade permitiu discussões com os alunos não apenas teóricas, porém notavelmente a realização do experimento em turma de Química Orgânica Experimental 2. Este trabalho consistiu no desenvolvimento de uma atividade em sala de aula sobre o tema, Incialmente os conceitos de Click Chemistry e Química Bioortogonal foram apresentados a partir do uso de slides, quadro e modelos moleculares modificados. Em seguida foi desenvolvido um kit para demonstração de uma reação de Click Chemistry em aula. O kit compreende todos os reagentes previamente fracionados e se mostrou prático e seguro para realização do experimento. Diversas discussões puderam ser realizadas com os alunos tais como a História do Prêmio Nobel, a importância industrial e biológica da Click Chemistry, bem como mecanismos de reações. Este trabalho dialogou com os conceitos de Ciência, Tecnologia e Sociedade (CTS).
Clinical Characteristics of Patients after Aryloxyphenoxy Propionate Herbicide Ingestion
Authors: Lim Junyeong , Moon Jeongmi , Chun Byeongjo
Published: June 2023

Purpose: No studies have been conducted to investigate the acute toxicity of aryloxyphenoxypropionate herbicides in humans following ingestion. Therefore, this study was conducted to investigate the clinical characteristics of aryloxyphenoxypropionate herbicide poisoning and provide guidance for physicians treating patients who have ingested these types of herbicides. Methods: A retrospective observational case series was conducted using ten patients with history of aryloxyphenoxy propionate herbicide. Data were collected for clinical manifestation, management and final outcome. Results: The most common symptoms were gastrointestinal irritation and an altered mental state (Glasgow Coma Scale<15). An elevated lactate level was a common laboratory abnormality, and prolonged QTc interval was commonly observed. These clinical features normalized within one day of supportive treatment. Conclusion: The acute toxicity of aryloxyphenoxypropionate herbicides in humans is manageable with supportive treatment. However, physicians should take into account depressed consciousness, the possibility of arrhythmia, and an elevated lactate level when planning their treatment strategy.
The Incidence, Associated Factors and Clinical Impact of Hyperamylasemia in Self-poisoning Patients
Authors: Seo Min Gu , Oh Sang Hoon , Lim Jee Yong , Kim Han Joon , Choi Se Min
Published: June 2023

Purpose: This study was conducted to investigate the incidence, associated factors and clinical impact of hyperamylasemia in self-poisoning patients. Methods: This study was based on a toxicology case registry of patients treated from 2009 to 2013 at a tertiary care university hospital. We retrospectively investigated the demographics, clinical variables, laboratory variables and intoxicants. Hyperamylasemia was defined as an elevation in serum amylase level to above the upper normal limit within 24 hours after admission. We analyzed the predisposing factors and clinical outcomes of patients in the hyperamylasemia group. Results: Hyperamylasemia was identified in 49 (13.3%) of the 369 patients. Using multivariate logistic regression, the odds ratios for HA were 3.384 (95% confidence interval, 1.142-8.013, p=0.014), 3.261 (95% confidence interval, 1.163-9.143, p=0.025) and 0.351 (95% confidence interval, 0.154-0.802, p=0.013) for pesticides, multi-drug use and sedatives, respectively. In the hyperamylasemia group, the peak amylase levels during 72 hours were correlated with the peak lipase levels (r=0.469, p=0.002) and peak aspartate aminotransferase levels (r=0.352, p=0.013). Finally, none of these patients had confirmed acute pancreatitis. Conclusion: Hyperamylasemia occurred rarely in these self-poisoning patients, and pesticide and multi-drug use were independent predictors of hyperamylasemia. Peak amylase levels were correlated with the peak lipase and aspartate aminotransferase levels.
Survey of Activated Charcoal Administration for Poisoning Patients Visited in Emergency Medical Centers and Emergency Staff's Perception in Korea
Authors: Bae Sung Jin , Choi Yoon Hee , Lee Duk Hee
Published: June 2023

Purpose: Activated charcoal (AC) has been widely used as a universal antidote. Currently, emergency medical centers in Korea cannot administer AC due to discontinuation of the supply of commercial ready-mixed AC suspension. This study was conducted to investigate the proportion of emergency medical centers that administer AC to poisoning patients and provide basic information for emergency physicians and toxicologists. Methods: A prospective telephone survey of all of the included emergency medical institutions was conducted. The type of emergency medical institution, average annual number of patients admitted to the emergency department, annual average number of patients who were poisoned and whether the hospital currently utilizes gastric lavage and administration of AC were determined. Results: AC was administered to poisoning patients in 40% of regional emergency medical centers, 59.3% of local emergency medical centers, and 45.9% of local emergency medical rooms. Overall, 37% of total emergency medical institutions did not administer AC due to discontinuation of the commercial ready-mixed AC suspension. Additionally, 77% of emergency physicians in institutions without AC knew AC is necessary for poisoning patients. The rate of vomiting experienced by the medical staff according to types of charcoal showed that the average rate of vomiting was 33% for commercial ready-mixed activated charcoal suspension and 51% for self-prepared charcoal powder (p=0.02). Conclusion: AC should be secured promptly in emergency medical institutions. Before the supply of commercial ready-mixed AC suspension becomes again it is essential to develop a standardized regimen for self-preparation of charcoal powder and to educate emergency physicians and toxicologists to its use.
A Fatal Case of Colchicine Poisoning
Authors: Ko Seung Hyun , Lee Gun Woo
Published: June 2023

Colchicine is a drug that has long been used to treat a variety of illnesses; however, it reportedly has adverse effects at apparent toxic doses as well as at lower and therapeutically recommended doses. The typical therapeutic dose of colchicine is up to 2.4 mg daily, although it is sometimes as high as 8-10 mg daily. Here, we describe a case in which the patient showed sudden deterioration and died because of unintentional colchicine poisoning with a relatively small dose. When a colchicine poisoned patient visits the hospital, the physician should identify the patient's colchicine poisoning dose and concomitant drugs. Moreover, the patients should be monitored intensively for 24 to 72 hours and managed with various supportive treatment methods early and actively.
Changes of Poison Data Characteristics Collected from Telephone Response in 1339 and 119: Discrepancy in Characteristics of Post-toxin Exposure Data Obtained through Telephone Counselling Provided by 1339 and 119
Authors: Park Kwang Hoon , Park Jong Su , Lee Sung-Woo , Kim Su-Jin , Han Kap Su , Lee Eui Jung
Published: June 2023

Purpose: The aim of this study was to compare the toxicologic profiles and outcome of poisoned patients by comparing the data obtained through telephone counselling, each provided by emergency medical information center (1339) and emergency dispatch center (119). Methods: We analyzed the telephone-based poison exposure data before and after Seoul 1339 merged to 119. We compared the Seoul 1339 call response data in 2008 with Seoul and Busan 119 call response data between 2014 and 2016. We analyzed the changes in the trend and quality of data obtained, as well as the quality of service provided by each center before and after this reallocation, by comparing the data each obtained through telephone counselling. Results: The data was collected for a total of 2260 toxin exposure related calls made to Seoul 1339 in 2009, and 1657 calls to 119 in Seoul and Busan between 2014 and 2016. Significant difference was observed for age, sex, and reason for exposure to toxic substance between the two groups. Conclusion: After the integration of 1339 with 119, 119 focused on role of field dispatch and hospital transfer, lacking the consulting on drug poisoning. Moreover, data on exposure to toxic substances at the pre-hospital stage indicate that drug information and counseling are missing or unknown. In addition, first aid or follow-up instructions are not provided. Thus, systematic approach and management are required.
Low-dose Intravenous N-acetylcysteine for the Prevention of Contrast-Induced Nephropathy in Emergency Patients Undergoing Computed Tomography
Authors: Lee Tae Wan , Kim Ji-Hoon , Choi Seung Pil
Published: June 2023

Purpose: To evaluate the effects of low-dose intravenous N-acetylcysteine on the prevention of contrast-induced nephropathy (CIN) in patients undergoing computed tomography (CT). Methods: All patients presenting to our emergency department and undergoing CT with intravenous contrast media between August 2014 and April 2016 were retrospectively enrolled. We included hospitalized patients with renal dysfunction [estimated glomerular filtration rate (GFR) between 30 and $89mL/min/1.73m^2$]. A 600-mg injection of N-acetylcysteine was given to patients once before and once immediately after CT, depending on the preference of physician. The primary outcome was CIN defined as an increase in creatinine level of ${geq}25%$ or ${geq}0.5mg/dL$ from the baseline within 48 to 72 hours after CT. A trained person blindly reviewed all medical records. Results: Of the 1903 admitted patients, CIN occurred in 9.8% of patients who received 1200 mg intravenous N-acetylcysteine (24/244) and 6.8% of patients who did not (113/1659, p=0.090). In a multivariable regression analysis, N-acetylcystine was not relevant to the prevention of CIN (odds ratio=1.42 [95% CI, 0.90-2.26]). Even in the stratified analysis using the propensity score matching, N-acetylcysteine was irrelevant (GFR 30-59: odds ratio=1.06 [95% CI, 0.43-2.60]; GFR 60-89: odds ratio=1.76 [95% CI, 0.75-4.14]). After adjustment, crystalloids were significantly associated with the reduction in CIN compared with dextrose water (odds ratio=0.60 [95% CI, 0.37-0.97]). Conclusion: No effect was found when low-dose intravenous N-acetylcysteine was used to prevent CIN. However, there seems to be an association between crystalloids and reduction in CIN.
Epidemiologic Characteristics of Intentional Poisoning: Emergency Department Based Injury in-depth Surveillance During 2011-2015
Authors: Lee Hak Soo , Han Juhee , Kim Ji Hoon , Kim Sunpyo , Kim Sun Hyu , Lee Ji Sook , Cho Gyu Chong , Han Chul , Park Joon Min , Chung Sung Phil , Kim Min Joung
Published: June 2023

Purpose: The purpose of this study was to investigate the epidemiologic characteristics of patients who visited emergency departments (EDs) after intentional poisoning in Korea. Methods: This study retrospectively analyzed the data of of 23 hospitals during a five-year period, between 2011 and 2015. We included patients who inflicted injury to themselves - attempt of suicide - by means of poisoning. Results: A total of 18,121 patients visited an ED after intentional poisoning. Among them, 58.3% were females; however, there were more males among those aged 60 years or older. The mortality rate for males was 8.6%, which was 3.1 times higher than that for females with 2.8%. The most common poison was pesticides (35.4%) in males and sedative-hypnotics (44.0%) in females. The most common causative agent of death was pesticide in both sexes (75.2% and 65.3%, respectively). Since the production of paraquat was discontinued in 2011, the number of deaths from pesticide poisoning has decreased. The mortality rate declined in both males and females, from 12.6% and 4.5% in 2011 to 7.1% and 2.1% in 2015, respectively. Conclusion: In this study, we analyzed the epidemiologic characteristics of intentional poisoning, especially the frequency of suicide attempts by gender and age group, the cause of suicide, and the causative agent. This can be used as basic data for establishing policies to reduce and prevent suicide attempts by poisoning.