bluuebunny/crossref_metadata_2025 huggingface dataset:
Multi-Emotion Features Extraction for Driver Distraction Detection
Authors: Chen Sheng-Tao , Hsia Chih-Hsien , He Yo-Cheng
Published: November 2024

Two major factors contributing to human-induced traffic accidents are driver fatigue and distraction. To reduce the rate of occurrence of car accidents, some studies introduced systems that record biometric measurements, diver behavior, and driver’s physical features while driving. Data obtained from these systems are used to predict the driver concentration states. However, these attention-detection systems face challenges in terms of applicability and accuracy in detecting negatively impacting driving behaviors. Contactless physical feature extraction and integration of deep learning are effective and applicable methods in this context. Therefore, this study proposes a method based on multi-feature processing in conjunction with you only look once (YOLO)-based object detection to classify driver attention. Experiments and validation were conducted using the open-source Yawn detection dataset (YawDD) and National Tsing Hua University drowsy driver detection dataset (NTHU-DDD). The proposed method not only outperforms those of certain studies and achieved high efficiency in detecting multi-emotion features of drivers and assisting driver attention.
Quantitative Evaluation for Robustness of Intelligent Fault Diagnosis Algorithms based on Self-attention Mechanism
Authors: Liu He , Wei Cheng , Sun Bo
Published: November 2024

Currently, various algorithmic models encounter numerous challenges in practical applications, such as noise, interference, and input changes, which can significantly impact their performance. Many methods have been proposed to enhance model robustness. However, to assess the effectiveness of these improvements, it is generally necessary to compare the model’s performance before and after applying the same noise and analyze the resulting changes. Moreover, evaluating the robustness of multiple models that meet basic requirements for a specific task requires qualitative analysis using specific indicators. This is especially crucial in fault diagnosis where multiple types of noise interference in the data can hinder accurate fault classification. Addressing this situation, this paper presents a quantitative evaluation method for the robustness of intelligent fault diagnosis algorithms based on the self-attention mechanism. The proposed method entails dividing the dataset into sub-datasets according to signal-to-noise ratio after injecting noise, separately calculating sub-indicators after training, dynamically assigning weights to these indicators using the self-attention mechanism and combining the weights of different sub-indicators to generate a comprehensive evaluation value for assessing robustness. The proposed method was validated through experiments involving three models, and the results demonstrated the reliability of this quantitative calculation approach for robustness.
Image Inpainting Method Based on Generative Adversary Networks
Authors: Zhang Zhao , Yan He , Wang Ping , Millham Richard , He Renjie
Published: November 2024

Aiming at the problems of missing and damaged image details, this paper proposes an image inpainting method that is preprocessed and then inpainted. First, through preprocessing that enhances and purifies the image, the clarity, saturation and contrast of the image are improved. Secondly, the image features are dynamically divided through the convolutional neural network, and the image is generated according to the principle of a generative adversarial network, finally, the adversarial strategy is used to promote the expression of the model, to make the repair result more realistic. Compared with other models, the method proposed in this paper has a better quality of repairing effect.
Acquisition of Cognitive Properties of Animal Cultural Words Based on Learners' Understanding and Output Performance
Authors: Lou Rongzhen
Published: November 2024

The mastery of the cultural connotation behind the language is one of the important criteria to measure the learners' language acquisition. The Cognitive property of words involves the cultural connotation behind the language, so it is necessary to apply the Cognitive property of words to the international Chinese education. This paper takes Chinese learners in Southeast Asian countries as the research object, and explores the Cognitive Properties of words from two aspects of learners' understanding and output. With the help of the corpus and the questionnaire survey method, it was found that Chinese learners have good understanding performance but poor output performance. The reasons are analyzed from the perspectives of mother tongue background, learning process and output environment, and put forward on teaching materials, teaching content and learning effect evaluation of Chinese teaching, in order to provide new ideas for the long-term development of international Chinese education.
Integrating Sports Tourism into Curriculum Design: Enhancing Experiential Learning in Educational Setting
Authors: Cheng Yubo , Wang Lin , Guan Hongguo
Published: November 2024

This paper explores the integration of sports tourism into curriculum design as a means of enhancing experiential learning in educational settings. Sports tourism provides students with opportunities to apply theoretical knowledge in real-world contexts, such as event management, marketing, and community engagement, while also fostering cultural understanding and personal development. The paper outlines theoretical frameworks for integrating sports tourism, discusses successful case studies, and identifies the benefits of experiential learning, including enhanced employability and personal growth. However, challenges such as limited resources and difficulties in assessment are also examined. The paper concludes by offering implications for educators and policymakers, as well as suggestions for future research on the long-term impacts of sports tourism in education and strategies for promoting inclusivity and accessibility.
Analysis of the Value Connotation and Development Path of Practical Education in Vocational Colleges
Authors: Chen Yonglin
Published: November 2024

Practice education is a new kind of educational mode in high vocational college, which is of practical meaning to enrich the connotation of educational system, to expand the methods of practical teaching and to innovate the measures of ideological and political work. This study discusses the value and connotation of practical education and analyzes the approaches to carry out practical education.
Blended Learning in English Education: A Comparative Study of Student Engagement and Learning Outcomes
Authors: Cai Jia
Published: November 2024

This study investigates the impact of blended learning compared to traditional instruction on student engagement and learning outcomes in English language education. Findings indicate that blended learning significantly enhances student engagement, leading to higher motivation and participation in both online and in-person activities. Additionally, students in blended learning environments show greater improvements in language skills, particularly in reading comprehension, vocabulary acquisition, and listening proficiency. The results suggest that incorporating digital resources into language education can create a more effective and engaging learning experience.
Exploring the Intersections of Design: A Comprehensive Analysis
Authors: li Guangyi
Published: November 2024

Design is a multifaceted discipline that intersects with various aspects of human life and industry. This paper delves into the broad and inclusive scope of design, examining foundational concepts, historical perspectives, product and industrial design, visual aesthetics, interaction design, sustainability, and cultural influences. By exploring these diverse domains, we aim to highlight the critical role of design in shaping our world and driving innovation.
An Exploration of Chinese College Students’ Attitudes toward ChatGPT’s Automated Written Corrective Feedback on English Essays
Authors: Zhang Xiaoyan , Cheng Zhi
Published: November 2024

This pilot study was conducted at a vocational college in Fuzhou, China, during the spring 2024 semester, to explore Chinese college students’ attitudes toward ChatGPT’s AWCF on a sample English essay. Twenty-seven college students majoring in Software Technology participated in the study and completed a survey via the WeChat survey app. SPSS and R Programming Language were used to analyze collected data. Survey results indicated that the participants generally have a positive view of ChatGPT’s feedback. While not all the participants believed ChatGPT identified more errors than they did, most of them acknowledged its effectiveness in correcting errors in the sample essay. It is worth noting that no significant differences in attitudes were found between the participants with and without ChatGPT experience, indicating that previous access to ChatGPT has not influenced their attitudes toward it. Interestingly, despite the overall positive attitudes toward ChatGPT, students varied significantly in their willingness to use it for learning English in the future. Overall, this study has implications for English teachers, especially college English teachers in China, to improve their English writing instruction.
Integrating Smart Technology into English Language Curriculum Enhancing Student Engagement and Learning Outcomes
Authors: Dou Anqi , Huang Cheng
Published: November 2024

This paper explores how the integration of smart technology into English language curricula enhances student engagement and improves learning outcomes. It begins by defining and illustrating the applications of smart technology in education, including tools such as artificial intelligence, apps, and virtual reality. The analysis then examines how these technologies foster interaction and participation, supported by relevant case studies. Furthermore, the paper discusses how smart tools aid in improving specific language skills and highlights the significance of adaptive learning and personalized feedback. Finally, data and research findings indicate that students utilizing smart technology show significant improvements in language proficiency. By effectively integrating smart technology, educators can create a more engaging and impactful learning environment for students.
Liquid Biofuel Production in Eastern Africa: The Sustainability Challenge of Land and
Feedstock Availability
Authors: Kedir Miftah F. , Doris Mutta
Published: November 2024

Liquid biofuel utilization is required to keep global warming below 2°C. In eastern African countries like Ethiopia, Sudan, Kenya, Tanzania, and Uganda, feedstocks for liquid biofuel production do not conflict with food crops. This study aimed to determine the land and feedstock availability for biofuel production in selected eastern African countries. In Ethiopia, 23.3 million ha of land area is suitable for biodiesel crops and 333,500 ha for bioethanol crops. Sudan has more than 60 million ha of land suitable for biofuel crops. In Tanzania, 435,000 ha of land was allocated for biofuel crops. In Uganda, 60% of the arable land area is ideal for Jatropha and 50% for sugarcane. About 20% of the potential arable land in Kenya is suitable for Croton. In 2009 Kenana Sudan Sugar Company launched 65 million litres of ethanol production. Tanzania was producing biodiesel for electricity. Uganda produced ethanol from sweet sorghum. Ethiopia and Tanzania can produce 35.588 and 7.089 billion liters of lignocellulosic ethanol, respectively, higher than their import of petroleum. However, other Eastern African countries, such as Burundi and Djibouti, had no liquid biofuel production in 2023. In eastern Africa, land and feedstock are widely available to produce biofuel for clean bioenergy that should be used in appropriate land use plan.

Keywords: biodiesel, bioethanol, feedstock, land, land use, productivity
Nutritional Assessment of Children and Adolescents with Isolated Ventricular Septal Defects after Closure
Authors: Salama Christine G. , El-Gharaz Mohamed H. , Sharaf Eman A. , Mostafa Fatma A. , Eldesouky Manar A.
Published: November 2024

Background: Children with congenital heart disease, including VSD, often start life with a normal birth weight. However, malnutrition and growth failure become apparent within the first few months. The energy intake and nutritional status of these children directly impact their growth, necessitating regular and meticulous follow- up from the moment of diagnosis, and extending for years after the defect has been corrected.The Aim: this study aimed to evaluate the nutritional status of children who have undergone surgical or interventional closure of isolated ventricular septal defects 6 to 12 months after closure.Methods: This study is a cross sectional observational included 50 patients were recruited form post cardiac interventional clinic (PCIC), Pediatric department Cairo university and October 6 university. All patients were subjected to Nutritional Assessment including objective and subjective global assessment, assessing length/height, weight, head circumference, BMI, skin fold thickness, and mid upper arm circumference. These parameters were plotted on WHO Z scores to detect malnutrition's type and degree. Nutritional Assessment by using the Subjective Global Assessment (SGA) form, that considers weight changes, food intake, functional status, and body composition, providing a holistic view of the child's nutritional health.Results: The mean age of the studied cases was 4.5 (±1.4 SD) with range (2.1-7.8) years, with 29 (58%) males. According to VSD size there were 8 (16%) moderate VSD and 42 (84%) large VSD. Membranous VSD was the most common type of VSD in 15 (30%). The mean age of VSD closure was 3.98y (±1.35 SD), according to method of closure. most of them were surgical 33 (66%) and 17 (34%) were interventional, The mean time interval between closure and assessment was 8 months (±2.14 SD). Among the studied cases according to subjective global assessment there were 8 (16%) A, 30 (60%) B and 12 (24%). Regarding weight for age on Z score 19 (38%) of the patients had moderate malnutrition lying bet (-2 to -3) and 1 patient (2%) had severe malnutrition less than (-3) on Zscore. Regarding MUAC 12 (24%) were moderately acute malnourished lying bet -2 to -3 and 10 (20%) were severely acute malnourished for age less than -3 on Z score. Regarding Ht for age on Z score 29 (58%) of the patients were above -2 on Z score while 42% were malnourished divided into 17 (34%) who suffers moderate stunting lies bet -2 to -3 on Z score and 4 (8%) had severe stunting for age less than -3.Conclusion: this study concludes that Malnutrition is still prevalent in patients after successful VSD closure and ongoing nutritional assessment is needed and SGA is a relevant tool in assessment of nutritional status of these children also Malnutrition in these patients is palpably multifactorial and not only due to the effect of VSD.
Development of AR-Based Educational Games for Mathematics Learning in Elementary Schools
Authors: Susanto Ruhiat , Nurtamam Mohammad Edy
Published: November 2024

The traditional approach to mathematics education in elementary schools often fails to engage students fully and can lead to a lack of interest in the subject. Augmented Reality (AR) technology presents a novel opportunity to enhance learning by integrating interactive, immersive experiences that can make mathematics more engaging and understandable for young learners. This study aims to develop and evaluate the effectiveness of AR-based educational games designed specifically for mathematics learning in elementary schools. The primary goal is to determine whether these games can improve students’ engagement and mathematical understanding compared to traditional teaching methods. A quasi-experimental design was employed, involving 150 elementary school students from three schools. Participants were divided into a control group, which continued with the standard curriculum, and an experimental group, which used the AR-based games. Data were collected through pre- and post-tests to assess mathematical understanding, as well as student engagement surveys. The findings revealed that students in the experimental group demonstrated significantly higher levels of engagement and improved test scores in mathematics compared to the control group. The AR games were particularly effective in enhancing students’ abilities to solve problems and understand complex mathematical concepts. The use of AR-based educational games in mathematics education can significantly enhance student engagement and understanding of the subject. This study suggests that incorporating AR technologies into the elementary school curriculum could be a beneficial strategy to revitalize mathematics education and improve learning outcomes.
Evolution and Challenges of Insurance Industry in Hong Kong: From a Backward Investment Channel to a Leading Financial Product
Authors: Zeng Dongxu
Published: November 2024

The objective of the study is to explore the growth trajectory of Hong Kong's insurance industry and its changing position in the financial market, this study uses historical literature analysis, market data analysis, and case studies to conduct an in-depth investigation of the development of Hong Kong's insurance industry from the 1980s to the present. The study found that the Hong Kong insurance industry has experienced a transformation from a marginal investment channel to a core financial product, and the product attributes have also undergone significant changes with market demand and technological progress. The analysis shows that the growth of the individual life insurance market is mainly driven by factors such as increased consumer awareness, market policy support, and stable economic environment. However, the study also identified challenges facing the industry, such as market saturation, regulatory changes, and declining consumer trust. Based on these findings, it is recommended to adopt diversified product strategies, strengthen consumer education, and improve service quality to maintain the vitality and sustainability of Hong Kong's insurance industry. The results of this study not only reveal the evolution law of the insurance industry, but also have important theoretical and practical significance for promoting the realization of financial freedom, enhancing industry competitiveness, and formulating future market strategies.
Evaluating the impact of seismic resilience of telecommunication tower by using time history analysis for with and without viscous damper
Authors: Meti Ashok , Malipatil Swapnil
Published: November 2024

The seismic behavior of viscous-damped telecommunication towers is evaluated using time history analysis. It is shown that the relative maximum peak displacement could be reduced to levels as low as 23% having an average 3% rise in acceleration as an acceptable trade-off. In the present study, dynamic time history analysis performed more effectively than the equivalent static analysis; even responses were significantly reduced in both X and Y directions. Peak displacements were thereby reduced by up to 77.6% and 94% in the X direction and by 94% and 78% in the Y direction, depending on the measurement point. Secondary analysis indicated that with the introduction of dampers displacements in the X and Y directions decreased by 62–82% and 61–81%, respectively. These results prove that the viscous dampers are a good application meant to neutralize effects from seismic forces, enhancing the structural system's resilience and ensuring the integrity of critical telecommunication infrastructure in seismic areas. The results show the value added by the viscous dampers to operational continuity and structure safety during the seismic event.
Learners Progressive Insight and Scholastic Triumphs Enhanced by School Facilities
Authors: Jamshaid Amber , Zaheer Hamna , Mukhtar Aamna , Baber Shafia , Roohi Tayyabah
Published: November 2024

The availability of basic facilities in institutes impact academic performance of students in all domains. Governments and societies around the globe strive to improve their educational systems so youth may avail the opportunity of reaching institutes to acquire the knowledge and skills, leading a healthy and constructive vivacity. Key inputs to the education system, such as curricula, trained teachers, sufficient institutional facilities and infrastructure, help to improve the quality of education. Present study emphasizes the impact measurement and evaluation of primary facilities in schools and their role in enhancing student educational growth and learning. The accessible population was selected based on research interest, centered on the non-probability convenience sampling. A total of eighteen key facilities were targeted and response analysis of participants was evaluated based on the hypothesis regarding impact of school facilities on student progress. Findings of present study conclude that educational achievements are negatively impacted by inadequate level of physical facilities and nonconductive learning atmosphere. Results highlighted critical interpretations where sufficient school infrastructure and strong child-parent interaction enhance progressive insight among students. These findings are evident as continuous improvement of school facilities build a foundation of institutional priming, optimizing learners overall growth and scholiastic triumphs.
PENDIDIKAN DAN LINGKUNGAN SOSIAL
Authors: Banatul Khoiriah  , Irpan Siregar Irpan Siregar , Dwi Puspita Sari Dwi Puspita Sari , Irvandy Anugrah Nasution Irvandy Anugrah Nasution
Published: November 2024

Pendidikan adalah proses yang berhubungan erat dengan transmisi pengetahuan, sikap, kepercayaan, keterampilan, dan aspek-aspek kelakuan lainnya kepada generasi muda. Dalam konteks ini, pendidikan mengajar dan membentuk pola-pola kelakuan manusia sesuai dengan harapan masyarakat. Penelitian ini bertujuan untuk menganalisis peran pendidikan dalam membentuk kelakuan sosial individu melalui interaksi di lingkungan keluarga, sekolah, dan masyarakat. Metode penelitian yang digunakan adalah penelitian kualitatif dengan pendekatan library research, dimana data dikumpulkan dari berbagai literatur yang relevan. Penelitian ini menemukan bahwa dalam masyarakat primitif, pendidikan formal tidak ada dan setiap anak belajar dari lingkungan sosialnya tanpa adanya guru tertentu yang bertanggung jawab atas kelakuannya. Namun, dalam masyarakat yang lebih maju, pendidikan formal di sekolah menjadi lembaga sosial yang penting dalam proses sosialisasi individu agar menjadi anggota masyarakat yang diharapkan. Pendidikan formal di sekolah memiliki peran besar dalam membentuk kepribadian individu, dimana hampir seluruh kelakuan individu dipengaruhi oleh orang lain. Selain itu, penelitian ini juga menyoroti pentingnya lingkungan pendidikan yang mencakup lingkungan keluarga, sekolah, dan masyarakat dalam memberikan pengaruh terhadap perkembangan anak baik secara sadar maupun tidak sadar.
PERAN GURU PENDIDIKAN AGAMA ISLAM DI ERA DIGITAL
Authors: Sri Lestari  , Jupriaman
Published: November 2024

Di era digital saat ini, akses terhadap informasi semakin mudah dan luas, memungkinkan peserta didik mengakses berbagai sumber, baik yang edukatif maupun yang negatif. Pendidikan menghadapi tantangan besar untuk tetap relevan dengan kemajuan zaman, sambil mempertahankan nilai-nilai agama Islam. Oleh karena itu, peran guru Pendidikan Agama Islam (PAI) sangat penting dalam membimbing siswa agar dapat meminimalisir dampak negatif dari era digital. Pendidikan merupakan aspek vital dalam perkembangan manusia, mempengaruhi pembentukan karakter dan intelektual anak. Berdasarkan UU Sisdiknas No. 20 Tahun 2003, pendidikan harus mengembangkan potensi spiritual, pengendalian diri, dan kecerdasan moral siswa. Guru PAI harus mampu memanfaatkan teknologi untuk mendesain pembelajaran yang kreatif dan interaktif, serta mengawasi penggunaan teknologi oleh siswa. Meskipun teknologi digital menawarkan banyak manfaat, seperti peningkatan efektivitas dan efisiensi, juga menimbulkan tantangan dalam bentuk akses terhadap konten negatif. Penelitian ini menggunakan pendekatan kualitatif deskriptif untuk menggambarkan strategi guru PAI dalam menanamkan nilai-nilai Islam di era digital. Temuan penelitian menunjukkan bahwa integrasi teknologi dalam pembelajaran agama Islam dapat meningkatkan motivasi dan akses informasi siswa, tetapi memerlukan pengawasan ketat untuk mencegah pengaruh konten negatif. Guru harus terus meningkatkan kompetensi digital mereka dan bekerja sama dengan orang tua untuk menciptakan lingkungan belajar yang mendukung perkembangan karakter dan moral siswa
RESENHA
Authors: Toledo Luis Marcio Arnaut de
Published: November 2024

RESENHA do livro do contos WILLIAMS, Tennessee. The Caterpillar Dogs and Other Early Stories. Tom Mitchell (Ed.). New York: New Directions, 2023. 112 p.
Pemberdayaan Kader Kesehatan dalam Deteksi Dini Gangguan Neuropaty pada Penderita DM di Desa Rasabou, Kecamatan Bolo, Kabupaten Bima
Authors: Kurniadi  , Sukmawati
Published: November 2024

Diabetes can lead to serious complications, one of which is neuropathy or nerve damage. This community service aims to enhance the knowledge of health cadres regarding the early detection of neuropathy disorders in diabetes mellitus. The methods employed include education through videos and booklets. The activities are divided into three phases: preparation, implementation, and monitoring, with the involvement of the partner, the village head, in gathering cadres and providing facilities for education. The activities took place in Rasabou Village, Bolo District, Bima Regency, in May 2024. The majority of health cadres are aged between 30 and 50 years, with high school as their highest education. Before the training, 12 cadres (70.6%) had a good understanding of diabetes. After the training, this number increased to 14 cadres (82.4%) with good knowledge. The conclusion indicates a significant improvement in the knowledge of health cadres following the education through lectures, videos, and simulations. The cadres showed high enthusiasm during the activities. It is recommended that future outreach methods be more interactive to enhance community understanding and participation in health programs.
ACTIVATES OF GLUTATION PEROXIDASE, GLUTATHION AND GLUTATION REDUCTASE IN HEALTHY AND DIABETES (INSULINE DEPENDENT) PATIENTS
Authors: Kozić А. , Popović М. , Ivetić V. , Pilija V.
Published: November 2024

Reduced glutathion (GSH), glutathion-reductase (GR) and glutathion-peroxidase (GSH-Px) are significant indicators of oxidative stress. Oxidative stress is a consequence of increased production of reactive oxygen radicals and/or on the other hand, insufficient antioxidative protection. It is well-known that free radicals have key role in the large number of biological phenomena, such as differentiation, transformation, signal transduction, aging etc., and they are important factors in pathogenesis of various diseases (carcinoma, diabetes, Alzheimer, Parkinson, aterosclerosis). This paper presents results of investigation of content of GSH and activities of GR and GSH-Px in healthy patients and diabetes insulindependent patients between 20 and 75 years of age in the region of Indjija. Correlation between investigated parameters in healthy persons and diabetics was found, as well as with results of similar investigations in other countries. Investigated sample comprised 200 healthy patients (20-75 years) divided into 5 groups, and 80 diabetes patients divided into 4 groups. Every group consisted of equal number of males and females. Above mentioned parameters were determined in hemolysate. Parameters change depending on patient age, and changes are more intense in all patients. Some differences exist in correlation of our results with results obtained in other regions.
EPIDEMIOLOGICAL CHARACTERISTICS OF MEASLES AFTER INTRODUCING THE VACCINE
Authors: Đorđević Z.
Published: November 2024

Measles are an acute infective disease highly contagious and belongs to the group of rush fevers. The aim of this paper is to examine the epidemiological characteristics of measles in Kosovo and Metohija after introducing the vaccine. The examination was carried out from 1987-1998. Because of the bad success after introducing the vaccine against measles in Kosovo and Metohija, which was not reached the issued minimum of 95% in either year, the measles have kept their epidemiological characteristics that they had in the prevaccinal period. The morbidity rate was in 1989. the highest (215.99 on 100000), and the lowest in 1995 (2.29 on 100000). Mortality rate was between 0-0.66 on 100000. It is very important that in those 4 years there were no dead cases. The cycles are still being registered by measles, with epidemic waves of 3-4 years. Seasons are also preserved, and the top of it is the month of January (291.3 patients on the average). Most patients belong to the preschool age (80.0%). Male children got more often ill (55.1%) than the female children.
PEMPHIGUS VULGARIS - THE CLINICAL MANIFESTATIONS AND COMPLICATIONS - case report
Authors: Krstić N. , Relić M. , Živanović J.
Published: November 2024

In this work the authors have treated patient with a wide range of skin symptomes and a various clinical sings and
manifestations of this serious bullous skin disease. The complications such as secondary bacterial infections on eroded
areas and swallow difficulties, because mucous membrane of oral cavity was affected, have supplemantary disabled quick
and efficient therapy. Therapeutical problems were presented as weakness, exhaustion, obstruction syndrome and asthmatic
constitution of a patient. The high doses of corticosteroids could provoke a hypertension, but still, with gradually reduced
doses of corticosteroids, supported by local therapy with antibiotics and corticosteroids, we achieved rehabilitation and
healing of our patient
EFFECTS OF GLUCAGON ON HEMODINAMIC VARIABLES IN CONDITIONS ON BLOCADE BETA ADRENORECEPTORS
Authors: Milanović Z. , Pavlović A. , Jovanović P. , Radović D. , Nestorović V. , Bursać M. , Smiljić S. , Mitić R.
Published: November 2024

Scientific research of effects of glucagon on the cardiovascular system have shown that glucagon has some
cardiostimulatory potential. The very interesting fact is that glucagon shows its cardiostimulatory effects by activating its
own, higly specific glucagonic receptors. That is way we wanted to research not only the effects of glucagon on the C.V.S.
but also its effects during the depression of the C.V.S. with high dosses of beta blocators (presolol) expecting a good
hemodinamic response. The experiment has been performed on two groups of 6 dogs. The first group of animal was treated
with i.v. bolus injections of glucagon and other group with presolol (15 mg/kg b.w.) i.v., and after that with i.v. bolus
injection of glucagon. Hemodinamic variables (mean arterial pressure, central venal pressure and hearth frequency) were
registred at the 1-st, 2-nd, 3-rd, 10-th, 20-th, 30-th and 40-th minute. The hearth frequency was registred by continous
monitoring, mean arterial pressure was registred with cateter in the arterial femoralis, while the central venal pressure was
registred over central venal cateter in v. femoralis. After the i.v. bolus injection glukagon shows higly positive effects,
followed by short-term increase of the mean arterial pressure, while the c.v.p. considerably falls. During the administration
of presolol the hearth frequency and mean arterial pressure fall considerably and progressively, while the c.v.p. rises
considerably. Glucagon, in conditions of c.v.s. depresion by high doses of presolol (15 mg /kg b.w.) considerably increases
hearth frequency and mean arterial pressure, while the c.v.p. falls considerably.
ANTIPYRETICAL EFFECT OF PARSLEY EXTRACTS (Petroselinum crispum L.) AT MICE
Authors: Bursać M. , Popović M. , Mitić R. , Bulajić S. , Stanojević Z. , Milanović Z.
Published: November 2024

With this work we intended to examine antipyretical effect of different extracts from the leaf. The following extracts were examined: etherical chloroformic The experiments were conducted on white laboratory mice, type BALB/C. Mice were divided in 5 groups, where each group received the appropriate extract. Rectal temperature was measured by "Termistorowy" termometer. After the temperatures were measured, for each of examined group we defined area under the curve. The area values were later used to determine statistically significant differences between them. Examination results of antipyretic effects of different extracts ( ) from the leaf, i parsley (Et O), (CHCl ), ethyl-acetic (EtOAC), n-bhutanolic (nBuOH), aquae- 2 3 ous (H O). 2 etherical (Et O), chloroformic (CHCl ), ethyl-acetic (EtOAC), n-bhutanolic (nBuOH), aquaeous (H O) parsley 2 3 2 n experiment with mice, show that all the extracts mentioned above, decreased (annuled) pyrogenic effect of 12% yeast suspension. 
PLACE OF SPECIFIC IMMUNOTHERAPY IN ALERGIC DISEASES TREATMENT
Authors: Smilić Lj. , Ristić-Vitaljić S. , Sovrlić B.
Published: November 2024

Specific immunotherapy (SIT) has been used for almost a century but its form of administration is still a matter of
debate. At present curative SIThas only demonstrated its efficiancy, under the conditions that an appropriate allergen extract
is used, and patients are careffuly selected. However, many alergic patients likely to respond to immunotherapy are not
treated specificaly, due to the prevaling opinion that immunotherapy is ineffective, and has more uneffectable side effects
than drug treatment. Direct comparison of efficiancy between immunotherapy and drugs is problematic as this implies a
comparison between a treatment aiming at interfering with the pathophysiological mechanisms of the alergic inflammation
with potential for long term effect, or even cure (immunotherapy), and a treatment abolishing symptoms whi-le being
administered, but without long term preventive capacity (drugs). In most patients the situation is not an either but ra-ther
both and. The advantages of combinig immunotherapy and drugs are related to a higher likelihood of increasing effi-ciancy,
reducing side effects, and improving patient compliance by combining a treatment having an immediate effect with one
functioning more slowly
FULMINANT HEPATITIS E - a case report
Authors: Milošev-Žilović D. , Marković M. , Maksin J.
Published: November 2024

Fulminant form of acute viral hepatitis E in adult patiens, except pregnants women, is very rare. The authors describe a 50 year-old man with diagnosis of viral hepatitis E on basis of antibodies found in IgM class to hepatitis E virus using ELISAtechnique. The disease had a fulminant course wich ended in death.
HISTOCHEMICAL LOCALISATION AND ACTIVITY OF DPP IV IN ANTIGEN STIMULATED TONSILLA
Authors: Savić S. , Savić S. , Avramović V. , Vlahović V.
Published: November 2024

Dipeptidyl peptidase IV is ecto-enzyme which is present on the cell surface of large number of cells and particularly of T-lymphocytes. It takes part in immune reactions and regulation of immune response, while antigen stimulation of cells increases percentage of expression of DPPIV on their cell surfaces. Since the immune response is different for chronic tonsillar disease of tonsilla palatine, idiopathic tonsillar hyperplasia ITH and recurrent tonsillitis RT, and considering the fact that DPPIV takes part in activation of T and B-lymphocytes stimulated by antigen, we presume that different activities of DPPIVexist in tonsillis and blood of persons diseased of different types of chronic tonsillitis, ITH and RT. The main goals of research are determination of activities of DPPIV on lymphocytes of tonsillas and serum of persons diseased of ITH and RT as well as histochemical and immunohistochemical determination of DPP IV localisation on lymphocytes of examed tonsillas. Two groups of patients are included: nineteen persons with ITH and thirteen persons with RT, while the control group was contained of thirty nine persons with diagnosis systematic lupus erythematosus (SLE) and fiftteen health persons. The research was done on 32 tonsillas created by tonsillectomia of persons with ITH and RT and 86 blood samples of all 86 persons. The results of research show histochemical localisation of enzyme activity of DPPIVin T-dependent zones of tonsilla and it is originating from activated T-lymphocytes. The enzyme activity of DPP IV on tonsillar lymphocytesis is higher in case of IHT compared with RT. By this research we conclude that deifferent activity of DPPIV on tonsillar lymphocytes for ITH and RTpresumes the difference of immuno response of tonsillas during these tonsillar diseases.
EVALUATION OF USAGE ANTIINFECTIVE MEDICAMENTS FOR SYSTEMATIC APLICATION ON THE BASIS OF DEFINED DAILY DOSE
Authors: Vojnović M. , Jakovljević Dž. , Jakovljević V. , Pilija V.
Published: November 2024

Defined daily dose (DDD) is arbitrary chosen technical unit for measuring medicament usage and it is not a recommended therapeutic dose. It is in fact a statistical parameter for monitoring medicaments usage, and it is related to the dose which is usually prescribed for the indication that the medicament was registered for. The aim of this work is to perform a detailed analysis of the extent and structure of the region of South Backa. Antiinfective medicaments in systematic use, according to the obtained data, participate with only 7.96 DDD/1000 inhabitants. The most applied pharmacotherapeutic subgroup with 2.99 DDD/1000 inhabitants is comprised of cephalexine and cephachlor. 
DYSPLASIO EPIPHYSIALIS MULTIPLEX - CASE REPPORT
Authors: Dejanović B. , Rašić D. , Antić G.
Published: November 2024

Dysplasio epiphysialis is congenital disorder of ossification and development of epiphysis that lead to deformation of epiphyses. This disorder of is not so frequent (1). Etiology is unknown. It appears in both sexes in the same percent, sporadically, but in the several members of one family also (2). It appears in two forms, polyarticular and oligoarticular. Clinical feature characterize low growing (150-160 cm) with short clumsy fingers, incrassate joints and limited mobility. Especially characteristic of this disorder is discrepancy between low degree of subjective complaints and marked radiological changes. (1). Laboratory findings most often are not specific. Metabolism of calcium and phosphorus is not changed (2). Radiological is characteristic irregular aspect of joint flanges and articulating surfaces and narrowing of the joint spaces, cartilage sclerosis, cystic changes in joints and, not so often periarticular chondromatosis. Vertebral joints if geared manifest platispondilia and ragged of vertebral joints surfaces (2). Conclusion: Dysplasio epiphysialis multiplex is characterized with specific clinical and radiological feature and appearance in jung ages; it is often substitute with primary generalized osteoarthrosis or rheumatoid arthritis (our case). From those reasons it is very important to recognize the specific nature of this disease for the therapeutic and prognostic purpose.
PHLEGMONA PERIURETHRALIS
Authors: Ivanović D. , Petronić D. , Stefanović G.
Published: November 2024

We presented you six patients suffering from phlegmona periurethralis. It is mens' disease and, in the greatest degree, it appears at stenosis and urethra trauma. The commonest case of this disease are patients suffering from diabetes and those who carry catheter all the time. The appliance of a large doses of antibiotics and early incision with drainage can help patients to be cured. Urine derivation is very important and it must be like minimal cystostomy
RARE INJURY OF BOTH TESTICLES CAUSED BY FIREARMS
Authors: Petronić D. , Stefanović G. , Ivanović D.
Published: November 2024

The injuries of genital organs are commonest today regarding to the fact that there are different kinds of firearms and contact mines, although testicles are well protected in thigh area. In cases where we have maximum testicles injuries the conservative surgical treatment should be applied, considering the fact that testicles have great power of "restitucio ad integrum".
CAUSES AND CONSEQUENCES OF SOCIALE DIFFERENCE FAMILY PLANING IN KOSMET
Authors: Petrović B.
Published: November 2024

In well organized societies, accept of material and technical progress, planning of the family and existing of human resources is of great importance. Every civilized society is tancing care of human potential, planning and progress, eather to stimulate or control of natural increase are bringing the suitable demographics of standards. With better family planning asspecially motivatiy the couples to decide for reproduction and delivering of optimal namber of children in optimal period between deliveries and in optimal ages, brings to decreased mortality among new-borns, and also their mathers. 
THE CHANGES IN BIOCHEMICAL BLOOD STRUCTURE AS A RESULT OF ACUTE DOG INTOXICATION WITH COPPER SULFATE
Authors: Vitošević B. , Kasanović K. , Radović D. , Pavlović A. , Mirić D. , Jovanović P. , Milanović Z.
Published: November 2024

It is known that the intoxication with heavy metals and pesticides is most often unmedical poisoning. In contrast to other heavy metals, for example: mercury, lead, cadmium and zinc, toxic copper activity and the mechanism of its effect are not known enough and they are not yet explained. Because of that, the aim of this work was ( with acute dog intoxication with copper sulfate ) to contribute to better clearing of biochemical mechanism as a result of copper toxical effect and to make analysis of its tissue distribution. Researching was done on adult dogs, both sexes, different races and body mass of 14- 20 kg, who were given a 10% water solution of copper sulfate in the dosage of 33mg/b.m. divided into 5 equal doses. The analysis of biochemical blood structure took the following things: total proteins, albumins, globulins, total lipids, chole2+ sterol, glucoze, transaminase (AST,ALT), catalase, peroxidase, vitamin C, proteine SH, the contretation of Cu in the serum 2+ and the content of Cu in the tissues. The results are presented in the charts and graphic presentation. All these changes can be the important directions in an biological monitoring as a biochemical indication of copper pollution in the surroundings.
METABOLIC SYNDROM, RISK FACTOR FOR CARDIOVASCULAR DISEASE
Authors: Novaković T. , Jovanović A. , Sovtić S. , Pajović S.
Published: November 2024

Sindrom X or Metabolic Syndrome are both terms used to describe a collection of herth risks contitions that increase your chance os developing heart disease, stroke and diabetes. The condition is aslo known by other names including insulin Resistence syndrome, and Dysmetabolic syndrome. The number of people with Metabolic Syndrome increases with
age, affecting more than 40 percent of people in their 60 s and 70 s. Components of Metabolic Syndrome are: Abdominal obesity, atherogenic dyslipidemia, raised blood pressure, insulin resistance, proinflamate state and prothrombotic state. The
National Cholesterol Education Program 's Adult Treatment Panel III report (ATPIII) identified 6 components of the metabolic syndrome that relevate to CVD. Insulin resistance is present in the majority of people with the matabolic syndrome.
It strongly associates is present with other metabolic risk factors and correlates unuvariately with CVD risk. Patiens with
longstanding insulin resistance frequently manifest glucose intolerance. When glucose intolerance evolves into diabetslevel hyperglicemia, independent risk factor for CVD. When 3 of 5 of the listed caracteristics are present, a diagnosis of metabolic syndrome can be made. The exact cause of Metabolic syndrome is not known. Most reserchers believe it is caused by
a combination of your genetic makeup and lifestyle choices-including the types of food you eat and level of physical activity.
INFLUENCE OF EMOTIONAL DISORDERS ON THE RECOVERY OF PATIENTS AFTER THE STROKE
Authors: Tomašević S. , Filipović D. , Naumović N. , Mišolić M.
Published: November 2024

The patients after the stroke besides impaired motor functions,often have cognitive and emotional disorders which
can endanger the successful carrying out of the rehabilitation treatment. The objective of this study was to estimate the
functional capability and to determine the cognitive and emotional disorders of the patients after the stroke. The research has
ecompassed 40 patients after the stroke of specified age and gender structure, treated in the Clinic for Rehabilitation, of the
Clinical Center in Novi Sad. The data have benn gathered from the anamnesis, clinical and neurological check, test of the
activity in everyday life, the findings of the psychologist on the emotinal status, as well as from the available medical
documentation about the patient. The average values of the Barthel's index are increased for 14.86% after the rehabilitation
treatment. The results show a strong presence of the emotional disorders with 57.5% of the patients. The increased values of Barthel's index and Mini Mental test at the end of the treatment show the undoubtfull importance of the rehabilitation
treatment in the recovery of the patients. The emotional disorders cause the worse recovery of the patients.
MICROBIOLOGICALLY FINDINGS AT SERONEGATIVE SPONDILOARTHROPATIES
Authors: Mekić M. , Ristić M. , Smilić Lj.
Published: November 2024

All formsspondyloarthropaties are uniteded with HLA-B27 antigen's in 70-100% in dependences of form illneses and so ethenic and eugenic qualifications. Consider that some Gram-negative bacteriums can have place in pathogenesis of spondyloarthropaties. Explored are 24 patients(15 men and 9 women) with seronegative spondyloarthropaties. Absence of
bacteriums which besides other factors inculpate for pathogenesis seronegative spondyloarthropaties in explored materials,
points to need for proving their antigens at synovium woof or anti-bodies in serum toward specific antigens.
COMPLEMENT - ACTIVATION, REGULATION OF ACTIVATION AND BIOLOGICAL ACTIVITY
Authors: Anðelković Z. , Mirić M. , Nestorović V. , Milanović Z. , Mitić R.
Published: November 2024

The complement system (complement) involves over 30 circulating and membrane-fixed proteins with an effector
role in the innate and humoral immunity. These proteins help the function of antibodies to protect the organism from foreign
molecules (antigens) which the term complement comes from. Soluble proteins of the complement system made mainly in
the liver and circulate in blood in an inactive form. The activation of complement may be initiated in three ways (classical,
alternative and lecitin pathway), and it is realized by sequential proteolysis of complement proteins (proenzymes) which
become emzymes with the proteolitic activity after cleavage. Products of the activatin of complement bind to the surface of
microbes or to the antibodies bound to antigens. An activated complement shows a number of biological effects, such as
lysis of an attached cell, opsonization, neutralization of viruses, inflammation, clearance of immune complexes etc. In contrast of microorganisms, human cells have a number of regulatory proteins which prevent the complement activation and in that way, they regulate its activity
MYOCARDITIS AND ENCEPHALITIS AS COMPLICATIONS OF TRICHINOSIS
Authors: Milošev-Žilović D. , Maksin J. , Marković M. , Jakovljević B. , Maslak S.
Published: November 2024

In February 2000, in Pancevo, 71 persons suffered from trichinosis. Of that number, 47 were hospitalized. In one of
the cases, which is a subject of this work, patient developed clinical feature of encephalitis. Encephalitis was diagnosed
based on clinical feature, EEG and spine fluid results. In the another case, that this work also deals with, toxic myocarditis
was developed. This diagnosis is based on clinical feature, changes in ECG and ultrasound of heart. Changes in ultrasound
of heart were noted 33 days after first symptoms had occurred.