bluuebunny/crossref_metadata_2025 huggingface dataset:
Spatiotemporal Simulation of Net Ecosystem Productivity and Its Response to Climate Change in Subtropical Forests
Authors: Zheng Junlong , Mao Fangjie , Du Huaqiang , Li Xuejian , Zhou Guomo , Dong Luofan , Zhang Meng , Han Ning , Liu Tengyan , Xing Luqi
Published: August 2019

Subtropical forests have great potential as carbon sinks; however, the relationship between net ecosystem productivity (NEP) and climate change is still unclear. This study took Zhejiang Province, a subtropical region, as an example. Based on remote sensing classification data of forest resources, the integrated terrestrial ecosystem carbon cycle (InTEC) model was used to simulate the spatiotemporal dynamics of the forest NEP in Zhejiang Province during 1985–2015 and analyze its response to meteorological factors such as temperature, precipitation, relative humidity, and radiation. Three patterns emerged: (1) The optimized InTEC model can better simulate the forest NEP in Zhejiang Province, and the correlation coefficient between the simulated NEP and observed NEP was up to 0.75. (2) From 1985 to 2015, the increase in the total NEP was rapid, with an average annual growth rate of 1.52 Tg·C·yr−1. During 1985–1988, the forests in Zhejiang Province were carbon sources. After 1988, the forests turned into carbon sinks and this continued to increase. During 2000–2015, more than 97% of the forests in Zhejiang Province were carbon sinks. The total NEP reached 32.02 Tg·C·yr−1, and the annual mean NEP increased to 441.91 gC·m−2·yr−1. The carbon sequestration capacity of forests in the east and southwest of Zhejiang Province is higher than that in the northeast of Zhejiang Province. (3) From 2000 to 2015, there was an extremely significant correlation between forest NEP and precipitation, with a correlation coefficient of 0.85. Simultaneously, the forest NEP showed a negative correlation with temperature and radiation, with a correlation coefficient of −0.56 for both, and the forest NEP was slightly negatively correlated with relative humidity. The relative contribution rates of temperature, precipitation, relative humidity, and radiation data to NEP showed that the contribution of precipitation to NEP is the largest, reaching 61%, followed by temperature and radiation at 18% and 17%, respectively. The relative contribution rate of relative humidity is the smallest at only 4%. During the period of 1985–1999, due to significant man-made disturbances, the NEP had a weak correlation with temperature, precipitation, relative humidity, and radiation. The results of this study are important for addressing climate change and illustrating the response mechanism between subtropical forest NEP and climate change.
Broadening Our Understanding of Hurricanes and Forests on the Caribbean Island of Puerto Rico: Where and What Should We Study Now?
Authors: López-Marrero Tania , Heartsill-Scalley Tamara , Rivera-López Carlos F. , Escalera-García Isabel A. , Echevarría-Ramos Mariangelí
Published: August 2019

Hurricanes shape ecosystems. A broad range of forested ecosystems is particularly affected by hurricanes, thus creating the need for studies addressing the effects of these disturbances. There is a long history of hurricane and forest research on the Caribbean island of Puerto Rico. In this study, we present results from a systematic literature review of peer-reviewed articles regarding ecological research conducted in Puerto Rico on the topic of hurricanes and forests published from 1900 through 2017. We present a summary of cyclonic activity on the island during the study period and the results from the systematic literature review within this cyclonic context. We discuss findings in terms of aspects of forests studied, geographical distribution of study areas, and time scales at which research was conducted. These findings allow us to determine what was studied about hurricanes and forests, identify gaps in the information, and suggest possible areas of research and production of new knowledge that recent and future storms can bring. We conclude with recommendations identifying research needs and propose additional approaches to complement existing information. Our goal is to generate future knowledge from hurricane and forest research with the broadest applications possible.
Physiological Responses to Abiotic and Biotic Stress in Forest Trees
Authors: Polle Andrea , Rennenberg Heinz
Published: August 2019

Forests fulfill important ecological functions by sustaining nutrient cycles and providing habitats for a multitude of organisms. They further deliver ecosystem services such as carbon storage, protection from erosion, and wood as an important commodity. Trees have to cope in their environment with a multitude of natural and anthropogenic forms of stress. Resilience and resistance mechanisms to biotic and abiotic stresses are of special importance for long-lived tree species. Since trees exist for many decades or even centuries on the same spot, they have to acclimate their growth and reproduction to constantly changing atmospheric and pedospheric conditions. In this special issue, we invited contributions addressing the physiological responses of forest trees to a wide array of different stress factors. Among the eighteen papers published, seventeen covered drought or salt stress as major environmental cues, highlighting the relevance of this topic in times of climate change. Only one paper studied cold stress [1]. The dominance of drought and salt stress studies underpins the need to understand tree responses to these environmental threats from the molecular to the ecophysiological level. The papers contributing to this Special Issue cover these scientific aspects in different areas of the globe and encompass conifers as well as broadleaf tree species. In addition, two studies deal with bamboo (Phyllostachys sp., [1,2]). Bamboo, although botanically belonging to grasses, was included because its ecological functions and applications are similar to those of trees.
Differential Trends of Qinghai Spruce Growth with Elevation in Northwestern China during the Recent Warming Hiatus
Authors: Wang Bin , Yu Pengtao , Zhang Lei , Wang Yanhui , Yu Yipeng , Wang Shunli
Published: August 2019

Tree growth strongly responds to climate change, especially in semiarid mountainous areas. In recent decades, China has experienced dramatic climate warming; however, after 2000 the warming trend substantially slowed (indicative of a warming hiatus) in the semiarid areas of China. The responses of tree growth in respect to elevation during this warming hiatus are poorly understood. Here, we present the responses of Qinghai spruce (Picea crassifolia Kom.) growth to warming using a stand-total sampling strategy along an elevational gradient spanning seven plots in the Qilian Mountains. The results indicate that tree growth experienced a decreasing trend from 1980 to 2000 at all elevations, and the decreasing trend slowed with increasing elevation (i.e., a downward trend from −10.73 mm2 year−1 of the basal area increment (BAI) at 2800 m to −3.48 mm2 year−1 of BAI at 3300 m), with an overall standard deviation (STD) of 2.48 mm2 year−1. However, this trend reversed to an increasing trend after 2000, and the increasing trends at the low (2550–2900 m, 0.27–5.07 mm2 year−1 of BAI, p > 0.23) and middle (3000–3180 m, 2.08–2.46 mm2 year−1 of BAI, p > 0.2) elevations were much weaker than at high elevations (3300 m, 23.56 mm2 year−1 of BAI, p < 0.01). From 2000–2013, the difference in tree growth with elevation was much greater than in other sub-periods, with an overall STD of 7.69 mm2 year−1. The stronger drought conditions caused by dramatic climate warming dominated the decreased tree growth during 1980–2000, and the water deficit in the 2550–3180 m range was stronger than at 3300 m, which explained the serious negative trend in tree growth at low and middle elevations. After 2000, the warming hiatus was accompanied by increases in precipitation, which formed a wetting–warming climate. Although moisture availability was still a dominant limiting factor of tree growth, the relieved drought pressure might be the main reason for the recent recovery in the tree growth at middle and low elevations. Moreover, the increasing temperature significantly promoted tree growth at 3300 m, with a correlation coefficient between the temperature and BAI of 0.77 (p < 0.01). Our results implied that climate change drove different growth patterns at different elevations, which sheds light into forest management under the estimated future climate warming: those trees in low and middle elevations should be paid more attention with respect to maintaining tree growth, while high elevations could be a more suitable habitat for this species.
Impact of Initial Planting Density on the Optimal Economic Rotation of Chinese Fir (Cunninghamia lanceolata (Lamb.) Hook) in an Experimental Forest Plantation
Authors: Liu Lin , Li Yan , Zhang Jianguo , Sun Honggang
Published: August 2019

The amount to be invested and the timing of clearcutting are central concerns in timber production. To assess the impact of the initial planting density on optimal economic rotation, we explicitly included the distribution of stand diameter classes and price differences representing the quality of stumpage in a model of forest land expected value (LEV). We selected five initial planting densities of 35-year old China fir (Cunninghamia lanceolata (Lamb.) Hook) plantations to fit the distribution of diameter classes along with stand age using a three-parameter Weibull theoretical growth model and then the Faustmann formula was used to calculate LEVs under different conditions. We found that the difference in the values of the growth rate of the stand volume and the discount rate affected the direction of the impact of initial planting density on the optimal economic rotation. If the value of the growth rate of the stand volume exceeded that of the discount rate, then the initial planting density had a negative impact on optimal economic rotation and vice versa. In addition, the quality effect, which means the shift in diameter class to a higher value attributed to the initial planting density, determined the extent of the impact of the initial planting density on the optimal economic rotation. The proportion of large-sized timber increased at a faster pace in accordance with the age of the stand in stands where the planting density was low compared with the proportion of such timber in stands with a higher initial planting density. The corresponding net stumpage price difference resulted in significant differences in LEVs. We concluded that a low-density stand of China fir was a preferred planting option for obtaining the highest LEV.
Application of GRAS Compounds for the Control of Mould Growth on Scots Pine Sapwood Surfaces: Multivariate Modelling of Mould Grade
Authors: Myronycheva Olena , Poohphajai Faksawat , Sehlstedt-Persson Margot , Vikberg Tommy , Karlsson Olov , Junge Helmut , Sandberg Dick
Published: August 2019

Research Highlights: In this study, the Generally Recognised as Safe (GRAS) compounds were applied in order to study mould-fungi growth on dried Scots pine sapwood. Background and Objectives: The transition to the use of more sustainable wood-material may be possible by applying GRAS compounds that can control and prevent contamination by primary colonising mould fungi. Materials and Methods: Kiln-dried sawn timber was treated with three different GRAS compounds, and different fungal inoculation methods applied in order to investigate differences in the development of fungal communities. Results: Substances based on potassium silicate significantly reduced fungal growth and mould contamination on the studied wood surfaces. By combining wood-surface treatments with GRAS compounds, fungal-area size as predictors and mould grade as response, a partial least squares (PLS) model that makes it possible to predict mould grade on wood surfaces was developed. The PLS model is a key component in the development of a smart grading-systems equipped by e.g. high-speed digital cameras for the early detection of fungal attack on wood surfaces in different applications. However, the measurements based on chemical characterisation should be the next step to take in order significantly to enhance the model and increase the range of robust applications. In the current study, a multivariate model describing the influence of each fungal-covering area on mould grade was presented for the first time.
Are We Defending the Indefensible? Reflecting on Policy and Practice Around ‘the Border’ in Plant Biosecurity for Tree Health
Authors: White Rehema M. , Marzano Mariella , Leahy Sharon , Jones Glyn
Published: August 2019

The challenges to forest health from climate change, globalization, contemporary trade practices and new recreational patterns require effective biosecurity. We asked: How is the biosecurity border for tree health understood and enacted by state and non-state actors? What are the consequences for tree health? Semi-structured interviews (N = 10) were conducted with scientists and other relevant actors (N = 21). The border was understood variously as: a biophysical boundary, often the coast; a geopolitical boundary, usually of the European Union; the points of main inspection focus; dispersed nodes of inspection; a ‘pre-border’ outside of UK; or by the location of detection activities. A wide range of state, non-state and hybrid groups are engaged in border practices. These practices have been altered due to trade and climate changes, are subject to cost and resource priorities and reflect particular knowledge flows and the biological nature of the agents. We suggest that there is an ‘everyone’ as well as ‘everywhere’ border that demands clarification of risks, roles and responsibilities, and we offer practical recommendations. We conclude that tree health border challenges are a manifestation of wider sustainability issues that enable us to explore human–nature relationships, democratic engagement and the pursuit of more sustainable futures.
Characterization of the Local Growth of Two Cantor-Type Functions
Authors: Prodanov Dimiter
Published: August 2019

The Cantor set and its homonymous function have been frequently utilized as examples for various physical phenomena occurring on discontinuous sets. This article characterizes the local growth of the Cantor’s singular function by means of its fractional velocity. It is demonstrated that the Cantor function has finite one-sided velocities, which are non-zero of the set of change of the function. In addition, a related singular function based on the Smith–Volterra–Cantor set is constructed. Its growth is characterized by one-sided derivatives. It is demonstrated that the continuity set of its derivative has a positive Lebesgue measure of 1/2.
Chromosomics: Bridging the Gap between Genomes and Chromosomes
Authors: Deakin Janine E. , Potter Sally , O’Neill Rachel , Ruiz-Herrera Aurora , Cioffi Marcelo B. , Eldridge Mark D.B. , Fukui Kichi , Marshall Graves Jennifer A. , Griffin Darren , Grutzner Frank , Kratochvíl Lukáš , Miura Ikuo , Rovatsos Michail , Srikulnath Kornsorn , Wapstra Erik , Ezaz Tariq
Published: August 2019

The recent advances in DNA sequencing technology are enabling a rapid increase in the number of genomes being sequenced. However, many fundamental questions in genome biology remain unanswered, because sequence data alone is unable to provide insight into how the genome is organised into chromosomes, the position and interaction of those chromosomes in the cell, and how chromosomes and their interactions with each other change in response to environmental stimuli or over time. The intimate relationship between DNA sequence and chromosome structure and function highlights the need to integrate genomic and cytogenetic data to more comprehensively understand the role genome architecture plays in genome plasticity. We propose adoption of the term ‘chromosomics’ as an approach encompassing genome sequencing, cytogenetics and cell biology, and present examples of where chromosomics has already led to novel discoveries, such as the sex-determining gene in eutherian mammals. More importantly, we look to the future and the questions that could be answered as we enter into the chromosomics revolution, such as the role of chromosome rearrangements in speciation and the role more rapidly evolving regions of the genome, like centromeres, play in genome plasticity. However, for chromosomics to reach its full potential, we need to address several challenges, particularly the training of a new generation of cytogeneticists, and the commitment to a closer union among the research areas of genomics, cytogenetics, cell biology and bioinformatics. Overcoming these challenges will lead to ground-breaking discoveries in understanding genome evolution and function.
Tumor-Infiltrating Leukocyte Composition and Prognostic Power in Hepatitis B- and Hepatitis C-Related Hepatocellular Carcinomas
Authors: Hsiao Yi-Wen , Chiu Lu-Ting , Chen Ching-Hsuan , Shih Wei-Liang , Lu Tzu-Pin
Published: August 2019

Background: Tumor-infiltrating leukocytes (TILs) are immune cells surrounding tumor cells, and several studies have shown that TILs are potential survival predictors in different cancers. However, few studies have dissected the differences between hepatitis B- and hepatitis C-related hepatocellular carcinoma (HBV−HCC and HCV−HCC). Therefore, we aimed to determine whether the abundance and composition of TILs are potential predictors for survival outcomes in HCC and which TILs are the most significant predictors. Methods: Two bioinformatics algorithms, ESTIMATE and CIBERSORT, were utilized to analyze the gene expression profiles from 6 datasets, from which the abundance of corresponding TILs was inferred. The ESTIMATE algorithm examined the overall abundance of TILs, whereas the CIBERSORT algorithm reported the relative abundance of 22 different TILs. Both HBV−HCC and HCV−HCC were analyzed. Results: The results indicated that the total abundance of TILs was higher in non-tumor tissue regardless of the HCC type. Alternatively, the specific TILs associated with overall survival (OS) and recurrence-free survival (RFS) varied between subtypes. For example, in HBV−HCC, plasma cells (hazard ratio [HR] = 1.05; 95% CI 1.00–1.10; p = 0.034) and activated dendritic cells (HR = 1.08; 95% CI 1.01–1.17; p = 0.03) were significantly associated with OS, whereas in HCV−HCC, monocytes (HR = 1.21) were significantly associated with OS. Furthermore, for RFS, CD8+ T cells (HR = 0.98) and M0 macrophages (HR = 1.02) were potential biomarkers in HBV−HCC, whereas neutrophils (HR = 1.01) were an independent predictor in HCV−HCC. Lastly, in both HBV−HCC and HCV−HCC, CD8+ T cells (HR = 0.97) and activated dendritic cells (HR = 1.09) had a significant association with OS, while γ delta T cells (HR = 1.04), monocytes (HR = 1.05), M0 macrophages (HR = 1.04), M1 macrophages (HR = 1.02), and activated dendritic cells (HR = 1.15) were highly associated with RFS. Conclusions: These findings demonstrated that TILs are potential survival predictors in HCC and different kinds of TILs are observed according to the virus type. Therefore, further investigations are warranted to elucidate the role of TILs in HCC, which may improve immunotherapy outcomes.
Further Defining the Phenotypic Spectrum of B3GAT3 Mutations and Literature Review on Linkeropathy Syndromes
Authors: Ritelli Marco , Cinquina Valeria , Giacopuzzi Edoardo , Venturini Marina , Chiarelli Nicola , Colombi Marina
Published: August 2019

The term linkeropathies (LKs) refers to a group of rare heritable connective tissue disorders, characterized by a variable degree of short stature, skeletal dysplasia, joint laxity, cutaneous anomalies, dysmorphism, heart malformation, and developmental delay. The LK genes encode for enzymes that add glycosaminoglycan chains onto proteoglycans via a common tetrasaccharide linker region. Biallelic variants in XYLT1 and XYLT2, encoding xylosyltransferases, are associated with Desbuquois dysplasia type 2 and spondylo-ocular syndrome, respectively. Defects in B4GALT7 and B3GALT6, encoding galactosyltransferases, lead to spondylodysplastic Ehlers-Danlos syndrome (spEDS). Mutations in B3GAT3, encoding a glucuronyltransferase, were described in 25 patients from 12 families with variable phenotypes resembling Larsen, Antley-Bixler, Shprintzen-Goldberg, and Geroderma osteodysplastica syndromes. Herein, we report on a 13-year-old girl with a clinical presentation suggestive of spEDS, according to the 2017 EDS nosology, in whom compound heterozygosity for two B3GAT3 likely pathogenic variants was identified. We review the spectrum of B3GAT3-related disorders and provide a comparison of all LK patients reported up to now, highlighting that LKs are a phenotypic continuum bridging EDS and skeletal disorders, hence offering future nosologic perspectives.
The Impact of Particulate Matter on Outdoor Activity and Mental Health: A Matching Approach
Authors: Jung Miyeon , Cho Daegon , Shin Kwangsoo
Published: August 2019

Exposure to air pollution affects human activity and health. Particularly, in Asian countries, the influence of particulate matter on humans has received wide attention. However, there is still a lack of research about the effects of particulate matter on human outdoor activities and mental health. Therefore, we aimed to explore the association between exposure to particulate matter with a diameter of less than 10 µm (PM10) and outdoor activity along with mental health in South Korea where issues caused by particulate matter increasingly have social and economic impacts. We examined this relationship by combining the physical and habitual factors of approximately 100,000 people in 2015 from the Korean National Health Survey. To measure each individual’s exposure to particulate matter, we computed the total hours exposed to a high PM10 concentration (>80 μg/m3) in a given district one month before the survey was conducted. After dividing all districts into six groups according to the exposed level of the high PM10, we applied the propensity score-weighting method to control for observable background characteristics. We then estimated the impact of the high PM10 on outdoor activity and mental health between the weighted individuals in each group. Our main findings suggest that the impact of PM10 on outdoor activity and stress shows an inverted-U shaped function, which is counterintuitive. Specifically, both outdoor activity and stress levels tend to be worsened when the exposure time to a high PM10 (>80 μg/m3) was more than 20 h. Related policy implications are discussed.
Field Study on the Microclimate of Public Spaces in Traditional Residential Areas in a Severe Cold Region of China
Authors: Lin Yujie , Jin Yumeng , Jin Hong
Published: August 2019

As residential environment science advances, the environmental quality of outdoor microclimates has aroused increasing attention of scholars majoring in urban climate and built environments. Taking the microclimate of a traditional residential area in a severe cold city as the study object, this study explored the influence of spatial geometry factors on the microclimate of streets and courtyards by field measurements, then compared the differences in microclimate of distinct public spaces. The results are as follows. (1) The temperature of a NE-SW (Northeast-Southwest) oriented street was higher than that of a NW-SE (Northwest-Southeast) oriented street in both summer and winter, with an average temperature difference of 0.7–1.4 °C. The wind speeds in the latter street were slower, and the difference in average wind speed was 0.2 m/s. (2) In the street with a higher green coverage ratio, the temperature was much lower, a difference that was more obvious in summer. The difference in mean temperature was up to 1.2 °C. The difference in wind speed between the two streets was not obvious in winter, whereas the wind speed in summer was significantly lower for the street with a higher green coverage ratio, and the difference in average wind speed was 0.7 m/s. (3) The courtyards with higher SVF (sky view factor) had higher wind speeds in winter and summer, and the courtyards with larger SVF values had higher temperatures in summer, with an average temperature difference of 0.4 °C. (4) When the spaces had the same SVF values and green coverage ratios, the temperature of the street and courtyard were very similar, in both winter and summer. The wind speed of the street was significantly higher than the courtyard in summer, and the wind speed difference was 0.4 m/s.
Differences and Similarities in Diabetes Research between China and the USA
Authors: Fan Hong , Bhurke Sheetal , Jia Guizhen , Song Fujian
Published: August 2019

Diabetes mellitus is one of the major non-communicable diseases (NCD) with increasing prevalence in China. There is a lack of high-quality research focusing on prevention and management of diabetes in low and middle income countries (LMICs) compared to developed countries. This comparative study aims to describe the characteristics of diabetes research conducted in China and the USA. The study included 800 studies on diabetes mellitus from both countries. Compared with studies in the USA, studies in China were more likely to be laboratory-based primary research (50.5% versus 30.8%), more likely to use animal subjects (47% versus 27.5%), more likely to focused on risk factors (22.7% versus. 14.7%), more likely to be case-controlled studies (17.7% versus 10.0%), and more likely to evaluate pharmacological treatments (36.5% versus 20.7%). Further, compared with studies in the USA, studies in China were less likely to involve patients (42.7% versus 60.7%), less likely to be clinical trials (6.2% versus 14.5%), less likely to be cohort studies (8.8% versus. 26.0%), and less likely to evaluate disease management interventions (3.3% versus 13.3%). Clinical studies in China should be more patient-based to facilitate more effective control and management of diabetes.
Patterns in the Occurrence and Duration of Musculoskeletal Pain and Interference with Work among Eldercare Workers—A One-Year Longitudinal Study with Measurements Every Four Weeks
Authors: Diana Nørregaard Rasmussen Charlotte , Karstad Kristina , Søgaard Karen , Rugulies Reiner , Burdorf Alex , Holtermann Andreas
Published: August 2019

The objective of this study was to examine patterns of musculoskeletal pain episodes over time. We conducted a one-year follow-up study among 275 eldercare workers with measurements of musculoskeletal pain (low back pain (LBP) and neck/shoulder pain (NSP)) and pain-related work interference (PWI) reported via text message every four weeks. We found a constant, high four-weekly prevalence of LBP and NSP (between 61% and 72%). The distributions of pain episodes for LBP and NSP were similar with approximately 30% of the episodes being 7 days or less per four weeks. There was also a high recurrence of pain, with 33% reporting LBP or NSP every four weeks. In addition, 24% had pain at every measurement in both the low back and neck/shoulder regions combined throughout the year. On days with LBP or NSP, approximately 59% also reported interference with work, and 18% of the eldercare workers reported that pain interfered with their work all measurements throughout the year. A high proportion of eldercare workers reported pain every four weeks throughout the year and the four-weekly prevalence of pain remained high and constant on a group level. During most days with pain, eldercare workers were hampered in their regular work activities.
Use of Flavored E-Cigarettes and the Type of E-Cigarette Devices Used among Adults and Youth in the US—Results from Wave 3 of the Population Assessment of Tobacco and Health Study (2015–2016)
Authors: Schneller Liane M. , Bansal-Travers Maansi , Goniewicz Maciej L. , McIntosh Scott , Ossip Deborah , O’Connor Richard J.
Published: August 2019

The United States (U.S.) Food and Drug Administration has expressed concern about flavored e-cigarettes (e.g., JUUL brand) because they are appealing to youth who may be unaware that the product is addictive. The Population Assessment of Tobacco and Health Study Wave 3 provided data on flavor categories, type of e-cigarette product, and smoking status among past 30-day youth and adult e-cigarette users in the US. Most past 30-day youth and adult users reported using only one flavor category, with fruit (53% youth, 31% adult) being the most commonly reported category. Adults were far more likely to report using tobacco flavor alone, compared to any other individual flavor category or flavor category combinations (OR: 21.08, 95%CI: 5.92, 75.12). Whereas, youth were more likely to report using multiple flavor categories (OR: 2.03, 95%CI: 1.55, 2.65), with the most reported pairing being fruit and candy (36%). The variety of flavors on the market appeals to consumers of all ages. Although most past 30-day e-cigarette users reported only one flavor category, non-tobacco flavors were far more common among youth. Differences in flavor preferences among adult versus youth vapers may have implications for the role of flavors in both the initiation of youth vaping and adult vaping for smoking cessation.
The Impact of Public Health Expenditure on Health Outcomes in South Africa
Authors: Hlafa Besuthu , Sibanda Kin , Hompashe Dumisani MacDonald
Published: August 2019

Health holds an important position in maintaining economic development since it is both a prerequisite for and an outcome of economic development. This means that health contributes greatly to the attainment of sustainable development and health outcomes. The importance of health is demonstrated in the Millennium Development Goals (MDGs) where three of the eight goals are aimed at improving health outcomes. Despite progress made by other middle-income countries in achieving health-related MDGs, South Africa is still worse off in respect of health outcomes and experiences a challenge in attaining positive outcomes for these goals. This study’s main focus was to identify the association between public health expenditure and health outcomes in South Africa’s nine provinces from 2002 to 2016. The study implemented fixed effects and a random effects panel data estimation technique to control for time effects and individual provincial heterogeneity. This was followed by employing the Hausman specification test to identify the fixed effects model as the appropriate estimator for the study. The study also employed the seemingly unrelated regression (SUR) model and the least squares dummy variable (LSDV) model to examine the impact of public health expenditure on each province separately. The findings elucidated that the relationship between public health expenditure and health outcomes in South Africa varied across provinces depending on provincial management and infrastructure availability.
Effect of Zn Addition on the Cd-Containing Anaerobic Fermentation Process: Biodegradation and Microbial Communities
Authors: Tian Yonglan , Zhang Huayong , Zheng Lei , Li Shusen , Hao He , Huang Hai
Published: August 2019

Anaerobic fermentation is considered as a cost-effective way of biomass waste disposal. However, the compound heavy metals contained in the biomass may induce complex effects on anaerobic fermentation, which limit the utilization of metal-contaminated biowaste. In this study, the impacts of Cd and Zn addition on biogas properties, process stability, substrate biodegradation, enzyme activity, and microbial properties were studied. The results showed that the addition of Cd together with Zn (Cd+Zn) increased the maximum daily and cumulative biogas yields, and brought forward the gas production peak compared with the Cd-added group. Taking the whole fermentation process into account, the promotion effects of adding Zn into the Cd-containing fermentation system on biogas yields were mainly attributable to better process stability, higher average NH4+-N concentration in the later stage of fermentation, reduced COD (p < 0.05), and increased biodegradability of lignocelluloses (p < 0.01), especially cellulose (p < 0.05) and lignin (p < 0.01). Meanwhile, the addition of Zn promoted the coenzyme M activity (p < 0.05), and increased the absolute abundance of Methanothermobacter. The bacteria communities during the fermentation process were responsible for the degradation of lignocelluloses. The results demonstrated that the addition of appropriate Zn into the Cd-containing fermentation system enhanced the efficiency of anaerobic fermentation and utilization of biowaste.
Periodontal Health and Use of Oral Health Services: A Comparison of Germans and Two Migrant Groups
Authors: Hagenfeld Daniel , Zimmermann Heiko , Korb Katja , El-Sayed Nihad , Fricke Julia , Greiser Karin Halina , Kühnisch Jan , Linseisen Jakob , Meisinger Christa , Schmitter Marc , Kim Ti-Sun , Becher Heiko
Published: August 2019

A cross-sectional study was performed with 251 individuals, consisting of 127 Germans, 68 migrants from Turkey, and 56 resettlers (migrants from the former Soviet Union with German ancestors) to compare periodontal health status, with a special focus on associations with lifestyle and anthropometric factors, and use of dental health services. Maximal pocket depth was used as a clinical surrogate marker for periodontitis. Other variables were obtained by questionnaires administered by a Turkish or Russian interpreter. The age- and sex-adjusted prevalence of periodontitis was significantly higher in Turks (odds ratio (OR) 2.84, 95% CI = 1.53–5.26) and slightly higher in resettlers (OR = 1.33, 95% CI = 0.71–2.49). These differences are partly explained by a differential distribution of known risk factors for periodontitis. A full model showed a higher prevalence of maximal pocket depth above 5 mm in Turks (OR = 1.97, 95% CI = 0.99–3.92). Use of oral health services was significantly lower in the two migrant groups. Individuals who reported regular visits to a dentist had significantly less periodontitis, independent of migrant status. A reasonable conclusion is that, since oral health causes major chronic diseases and has a major effect on total health system expenditures, public health efforts both generally and specifically focused on migrant groups are warranted.
Does the Mode of Exercise Influence the Benefits Obtained by Green Exercise?
Authors: Fraser Matthew , Munoz Sarah-Anne , MacRury Sandra
Published: August 2019

Green exercise studies have tended to use walking as a modality of exercise to establish benefits to mental health. Whether green exercise benefits translate into different forms of green exercise has been deemed an important research gap. A mixed-methods study design was used to compare psychological responses between two forms of green exercise; golf and walking. A total of 20 participants (10 in each group), with a range of ages and experience were recruited to take part in the study. Participants in the walking condition exhibited significantly greater levels of dissociative cognitions than golf condition participants. Consequently, only the walking condition significantly improved in a directed attention test. Results from the Exercise-Induced Feeling Inventory questionnaire found the walking condition demonstrated increases in all four subscales, whereas the golf condition showed no significant improvements. Based on the findings from the qualitative analysis, distinct differences were seen with regards to the perception of the environment. Participants in the golf condition noted natural elements as obstacles to effective performance, whereas the walking group noted natural stimuli as evoking positive feelings. In agreement with the Attention Restoration Theory, the current study demonstrates that the benefits of green exercise are somewhat reduced when greater levels of directed attention towards the activity are exhibited during green exercise.
Social Determinants and Disparities in Active Aging Among Older Taiwanese
Authors: Hsu Hui-Chuan , Liang Jersey , Luh Dih-Ling , Chen Chen-Fen , Wang Ying-Wei
Published: August 2019

This study assesses equity in active aging across social determinants among older Taiwanese. The data were collected from face-to-face interviews with adults aged 55 years or more in Taiwan in 2017 (n = 738). A total of 30 individual-level Taiwan active aging indicators were chosen, and the relationship between social determinants and active aging indicators were analyzed by logistic regression models. Women were more likely to participate in volunteering and other social groups and in lifelong learning activities, whereas men were more likely to be employed, to engage in physical activity, to feel safe from violence, and to use preventive care. Higher education was related to higher employment, social participation, independent living, lifelong learning, and a lower likelihood of poverty and severe cognitive impairment. Those living in rural areas were more likely to be employed, perform physical activity, feel physically safe, have better mental well-being, and have higher social respect and social integration ratings, whereas living in urban areas was related to greater access to medical care, owning assets, less severe cognitive impairment, greater likelihood of using information and communications technology, higher level of education, and higher access to convenient transportation. The significant disparities that exist in active aging may suggest inequality.
Characterization of Intelligence in Children with Exotropia
Authors: Sun Tao , Wang Zhonghao , Shen Tao , Yan Jianhua , Xie Chuanbo , Li Xiuhong
Published: August 2019

The effect of exotropia on the intelligence of children is unknown. This study aimed to assess the intelligence in children with exotropia and investigate the influence of the main clinical indexes of strabismus on intelligence. Eighty-four participants aged 8–12 years were enrolled, including 37 patients with exotropia (exotropia group) and 47 normal individuals (normal group). Intelligence was assessed by the Wechsler Intelligence Scale for Children—Fourth Edition (WISC-IV), including the Verbal Comprehension Index (VCI), Perceptual Reasoning Index (PRI), Working Memory Index (WMI), Processing Speed Index (PSI), and Full-Scale Intelligence Quotient (FSIQ). The exotropia group had a significantly lower PRI score but a higher PSI score than the normal group. However, there was no significant difference in the WMI, VCI, and FSIQ between groups. Multiple linear regression showed that PRI–WMI and PRI–PSI differences were significantly lower in the exotropia group. Inter-subscale correlations analysis showed that the pattern of intelligence structure was different between groups. The type of exotropia, angle of deviation, duration of symptoms, and stereoacuity had no effect on the intelligence of children with exotropia. Children with exotropia had a relatively worse performance in the perceptual reasoning skill but a better processing speed and a different pattern of intelligence structure.
Diet and Non-Alcoholic Fatty Liver Disease: The Mediterranean Way
Authors: Abenavoli Ludovico , Boccuto Luigi , Federico Alessandro , Dallio Marcello , Loguercio Carmelina , Di Renzo Laura , De Lorenzo Antonino
Published: August 2019

Lifestyle interventions remain the first-line treatment for non-alcoholic fatty liver disease (NAFLD), even if the optimal alimentary regimen is still controversial. The interest in antioxidants has increased over time, and literature reports an inverse association between nutrients rich in antioxidants and the risk of mortality due to non-communicable diseases, including NAFLD. Mediterranean diet (MD) is a model characterized by main consumption of plant-based foods and fish and reduced consumption of meat and dairy products. MD represents the gold standard in preventive medicine, probably due to the harmonic combination of many foods with antioxidant and anti-inflammatory properties. This regimen contributes substantially to the reduction of the onset of many chronic diseases as cardiovascular diseases, hypertension, type 2 diabetes mellitus, obesity, cancer, and NAFLD. The present review aims to clarify the intake of antioxidants typical of the MD and evaluate their effect on NAFLD.
Government Initiative in Brazilian Public Health: A Technology Transfer Analysis
Authors: Gomes Myller Augusto Santos , Kovaleski João Luiz , Pagani Regina Negri , Zammar Gilberto
Published: August 2019

The objective of this research is to analyze the transfer of technology developed by the commercial and industrial compensation policy of the initiative of the Plan of Expansion of Radiotherapy of the Ministry of Health. The data of the organization subsidized by the Plan of Expansion of Radiotherapy were obtained through research documentary, interviews with professionals and participant observation. The methodological strategy consisted of a case study supported by a cross-sectional study, the internal environment was analyzed with variables found in the literature, allowing its comprehension in a certain hospital situation. The results revealed that the initiatives of introduction of radiotherapy equipment by the Expansion Plan suffered numerous confrontations within the contextual and organizational circumstances that affected its development and effectiveness. Given the struggles of the Expansion Plan at the tactical and operational levels of decision-making, there are challenges that require responses from organizations involved in the process to implement the trade agreement established by the compensation policy, with the initial stage being highlighted as a technology transfer process. Due to management skills and expertise, it gives you the paradigm status to be followed based on the relevant dimensions and indicators of the technology transfer analysis.
The Influence of Standardized Residency Training on Trainees’ Willingness to Become a Doctor: A Comparison between Traditional Chinese Medicine and Western Medicine
Authors: Yang-Huang Junwen , Qian Wenji , Zhang Kan , Shi Lu , Huang Jiayan
Published: August 2019

A standardized residency training program (SRT) was launched in Shanghai in 2010, for both Western Medicine (WM) and Traditional Chinese Medicine (TCM). This study aimed to assess whether the program impacted trainees’ willingness to become a doctor and whether the program had different effects among WM and TCM trainees. A structured questionnaire was distributed to 2114 trainees to assess their perceptions and satisfaction with the program and their willingness to become a doctor after the exposure to the program. The trainees’ characteristics were compared between WM and TCM specialties using X2 tests. The potential factors associated with trainees’ perception of the program and willingness to become a doctor after the exposure to the SRT program were assessed by multiple linear and logistic regression models. Compared to WM trainees (n = 1853), TCM trainees (n = 261) would be more likely to become doctors if there were no SRT program (p = 0.003). Both individual and program-wide (different specialties) factors contributed to trainees’ perception, overall satisfaction, and willingness. Only specialty played an independent role in the associations with all three outcome variables. Inequality of characteristics between TCM and WM trainees reduced TCM trainees’ willingness to become a doctor after the exposure to the SRT program.
Childhood Undernutrition and Its Predictors in a Rural Health and Demographic Surveillance System Site in South Africa
Authors: Modjadji Perpetua , Madiba Sphiwe
Published: August 2019

Background: Overweight and obesity are increasing at an alarming rate in South Africa, while childhood undernutrition remains persistently high. This study determined the magnitude and predictors of stunting and underweight among schoolchildren in the Dikgale and Health Demographic Surveillance System Site, a rural site in South Africa. Methods: A cross sectional study using multistage sampling was conducted among 508 schoolchildren and their mothers. Anthropometric measurements were taken from children and their mothers, while sociodemographic information was obtained from mothers using a questionnaire. The World Health Organization Anthro Plus was used to generate height-for-age and weight-for-age z-scores to indicate stunting and underweight, respectively, among the children. Maternal overweight and obesity were assessed using body mass index. Bivariate and multivariate logistic regression analyses were used to evaluate the predictors of stunting and underweight among schoolchildren. Results: Twenty-two percent (22%) of children were stunted and 27% were underweight, while 27.4% of the mothers were overweight and 42.3% were obese. The odds of being stunted were lower in younger children, whereas having a mother who was overweight/obese and had a short stature increased the odds of stunting. Access to water, having a refrigerator, and having a young mother were protective against being underweight. Having a mother who was overweight/obese increased the odds of being underweight. Conclusions: The study showed a high prevalence of stunting and underweight among children, and overweight and obesity among mothers, indicating a household double burden of malnutrition. The age of the child and maternal overweight/obesity and short stature were predictors of stunting and underweight, while having a younger mother and access to water and a refrigerator were protective against being underweight. The need for an evidence-based and feasible nutrition program for schoolchildren, especially those in rural schools, cannot be over-emphasized.
Health Effects of Energy Intensive Sectors and the Potential Health Co-Benefits of a Low Carbon Industrial Transition in China
Authors: Yang Tingru , Liu Wenling
Published: August 2019

Background: The issues of environmental pollution and its effects on health have become increasingly serious in China. Energy intensive sectors are not only the main energy consumers, but also the main sources of air pollution. Analyzing the health effects of energy intensive sectors and the potential health co-benefits of a low carbon industrial transition is of great importance for promoting China’s air pollution control. Methods: This study used the exposure-response (ER) relationship model and inhalation factor methods to quantitatively analyze the health effects of air pollution and forecast the potential health co-benefits in the power and steel sectors. Results: The results showed that in 2016 SO2 and PM2.5 emissions caused about 850,000 premature deaths, and 10 million cases of respiratory diseases and chest discomfort, resulting in health-related economic losses of 1.2 trillion Yuan, accounting for 1.6% of the GDP. Meanwhile, demand control in consumption could significantly reduce SO2 emissions in the power and steel sectors, thus offering significant health co-benefits. However, there was still some uncertainty regarding the reduction of PM2.5 emissions in the steel sector. Conclusions: There is a need to take advantage of the health co-benefits of emission reduction in energy intensive sectors and to adopt flexible means to stimulate their green transformation.