bluuebunny/crossref_metadata_2025 huggingface dataset:
The Occipital Face Area Is Causally Involved in Facial Viewpoint Perception
Authors: Kietzmann Tim C. , Poltoratski Sonia , König Peter , Blake Randolph , Tong Frank , Ling Sam
Published: December 2015

Humans reliably recognize faces across a range of viewpoints, but the neural substrates supporting this ability remain unclear. Recent work suggests that neural selectivity to mirror-symmetric viewpoints of faces, found across a large network of visual areas, may constitute a key computational step in achieving full viewpoint invariance. In this study, we used repetitive transcranial magnetic stimulation (rTMS) to test the hypothesis that the occipital face area (OFA), putatively a key node in the face network, plays a causal role in face viewpoint symmetry perception. Each participant underwent both offline rTMS to the right OFA and sham stimulation, preceding blocks of behavioral trials. After each stimulation period, the participant performed one of two behavioral tasks involving presentation of faces in the peripheral visual field: (1) judging the viewpoint symmetry; or (2) judging the angular rotation. rTMS applied to the right OFA significantly impaired performance in both tasks when stimuli were presented in the contralateral, left visual field. Interestingly, however, rTMS had a differential effect on the two tasks performed ipsilaterally. Although viewpoint symmetry judgments were significantly disrupted, we observed no effect on the angle judgment task. This interaction, caused by ipsilateral rTMS, provides support for models emphasizing the role of interhemispheric crosstalk in the formation of viewpoint-invariant face perception.

SIGNIFICANCE STATEMENTFaces are among the most salient objects we encounter during our everyday activities. Moreover, we are remarkably adept at identifying people at a glance, despite the diversity of viewpoints during our social encounters. Here, we investigate the cortical mechanisms underlying this ability by focusing on effects of viewpoint symmetry, i.e., the invariance of neural responses to mirror-symmetric facial viewpoints. We did this by temporarily disrupting neural processing in the occipital face area (OFA) using transcranial magnetic stimulation. Our results demonstrate that the OFA causally contributes to judgments facial viewpoints and suggest that effects of viewpoint symmetry, previously observed using fMRI, arise from an interhemispheric integration of visual information even when only one hemisphere receives direct visual stimulation.
Geometric characteristics of Iraq’s raster topographic maps used for automatic updating the road network
Authors: Abdallah Rang
Published: December 2015

This paper is devoted to the problem of road network extraction from raster image. The task of
road network extraction is formulated in common view. The approach to the road map extraction has been proposed which can be applied for topographic map updating and is based on
image clustering by k-means method and on application of scanning algorithm for extraction of
road network fragments. Road map description is formed as set of linear fragments with knowing parameters. These linear fragments are created by merging of smaller parts. Experimental
researches were implemented for maps of 10 Iraq cities. Experimental results show in average
the extraction precision of 86% (in comparison with human expert).
Invasive Reed Canarygrass (Phalaris arundinacea) and Native Vegetation Channel Roughness
Authors: Martinez Adriana E. , McDowell Patricia F.
Published: December 2015

In instances where vegetation plays a dominant role in the riparian landscape, the type and characteristics of species, particularly a dominant invasive, can alter water velocity at high flows when vegetation is inundated. However, quantifying this resistance in terms of riparian vegetation has largely been ignored or listed as a secondary characteristic on roughness reference tables. We calculated vegetation roughness based on measurements of plant stem stiffness, plant frontal area, stem density, and stem area of three dominant herbaceous plants along the Sprague River, Oregon: the invasive reed canarygrass, native creeping spikerush, and native inflated sedge. Results show slightly lower roughness values than those predicted for vegetation using reference tables. In addition, native creeping spikerush and invasive reed canarygrass exhibit higher roughness values than native inflated sedge, which exhibits values lower than the other two species. These findings are of particular importance where the invasive reed canarygrass is outcompeting native inflated sedge, because with invasive colonization, roughness is increasing in channel zones and therefore is likely changing channel processes. Direct depositional measurements show similar results.
Strawberry Tolerance to Bed-Top and Drip-Applied Preemergence Herbicides
Authors: Boyd Nathan S. , Reed Thomas
Published: December 2015

Broadleaf weeds and nutsedge are persistent problems with limited management options for strawberry growers in Florida. Experiments were conducted in 2012 to 2013 (year 1) and 2013 to 2014 (year 2) at the Gulf Coast Research and Education Center in Wimauma, FL, to evaluate tolerance of two strawberry cultivars (‘Strawberry Festival' and ‘WinterStar'™) to PRE herbicides applied on the bed top or injected through the drip tape. The bed-top herbicides were applied to formed beds following fumigation but prior to laying the plastic mulch. Herbicides evaluated included two rates of EPTC, fomesafen, halosulfuron, and S-metolachlor as well as tank mixes of EPTC + S-metolachlor, fomesafen + S-metolachlor, and napropamide + oxyfluorfen. Drip-applied herbicides were applied through a single drip tape and strawberries were transplanted 1, 7, 15 and 30 d following application. Drip-applied herbicides included two rates of EPTC and fomesafen as well as two rates of a tank mix of napropamide + oxyfluorfen. None of herbicides applied on the bed top except S-metolachlor 214 g ai ha−1 consistently injured either strawberry cultivar or impacted yields. None of the drip-applied herbicides damaged the strawberry plants or reduced yields at all planting dates. In year 1, EPTC at 229 g ai ha−1 and EPTC at 229 g ha−1 + S-metolachlor at 107 g ha−1 resulted in a 70 to 86% reduction in purple nutsedge density compared to the nontreated control. No differences in nutsedge density among treatments were observed in year 2. The herbicides evaluated are safe for use on strawberry and would provide growers with alternative herbicide options, application timings, and application techniques. Further research is needed to evaluate efficacy.
International research for the betterment of children worldwide
Authors: Szécsi Tünde
Published: December 2015

The book “Early Childhood Education: International Research Report” edited by László Varga is a unique and successful demonstration of global efforts for the betterment of children worldwide. This joint research initiative brought researchers and practitioners from the field of early childhood together to explore the context and culture of childhood as perceived by children, and current and future educators. In sixteen chapters, authors from eight countries across three continents – Europe, Asia and America – investigated diverse aspects of childhood and child development, such as children stories, play, project approach and traditional and non-traditional learning environments. The purposeful selection of countries and authors allows the reader to gain insights into early childhood trends and practices in diverse cultures. The studies conducted in various countries – Croatia, Czech Republic, Greece, Spain, Turkey, The United Kingdom, Thailand and the United States of America – target the local context of childhood; however the context-specific findings carry features of similarities
A paraszti létmód tudatformáinak leképeződése Koszta József leánygyermek-ábrázolásain
Authors: Támba Renátó
Published: December 2015

Dolgozatomban az alföldi pusztaság festője, Koszta József leánygyermek-ábrázolásainak gyermekkép-történeti szempontú elemzésére vállalkozom, abból a célból, hogy rávilágítsak az archaikus paraszti társadalom körében élő gyermekkép néhány lényeges vonására, a leánygyermekeket övező gyermekségkonstrukciókat illetően. A szemlék során kompozícióelemzési, tartalomleírási, antropológiai szempontokat egyaránt érvényesítek, hogy mindezek nyomán aztán következtetéseket tehessek a gyermekképre vonatkozóan. Így a látottak (kor, nem, elhelyezkedés, kompozícióban betöltött szerep, tevékenység) leírásán túl rögzítésre kerülnek a szociokulturális kontextusra utaló jelek (tárgyi-fizikai környezet: táj, enteriőr, ruházat) is, illetve mindezek után tehetünk következtetéseket a már kislánykorban érlelődőben lévő, a leányideállal kapcsolatos értékekre, magatartásbeli elvárásokra vonatkozóan.
A gyerekek játékokhoz fűződő érzelmi kapcsolata
Authors: Zsubrits Attila , Valkó Anna , Horváth Krisztina , Fehér Annamária
Published: December 2015

A korai személyiségfejlődésben kitüntetett jelentőségű a közeli kapcsolatokban megszerezhető érzelmi biztonság. A gondoskodó személyekhez való kötődés fokozatosan kiegészül a környezet felé irányuló ragaszkodással. A személyek, a helyek és a tárgyak melletti elköteleződések után az egyes tevékenységekben ugyancsak újra és újra átélhetők lesznek az ismerős érzelmek. A tevékenységek közül különösen a játszás az a tevékenység, ami hosszú időn keresztül meghatározza a gyerekek mindennapi életét. A tanulmányban az interperszonális kötődéselméletből kiindulva a helykötődés, a tárgykötődés és a tevékenységhez való ragaszkodás jelenségét értelmezzük, amelyhez kapcsolódóan elemezzük a játékfejlődést, valamint a gyerekek játéktevékenységekhez és játéktárgyakhoz fűződő kapcsolatát. Az elméleti rendszerezést óvodáskorú gyerekek körében elvégzett empirikus kutatási eredmény egészíti ki.
180 éve született dr. Waisbecker Antal
Authors: Balogh Lajos , Keszei Balázs
Published: December 2015

Dr. Waisbecker Antal Vas vármegye tisztifőorvosa és a XIX–XX. század fordulóján a megye legjelentősebb botanikusa volt. A megye botanikai monográfiáját jegyző Borbás Vincét is jelentős florisztikai adatokkal segítette. Tanulmányaiban többek között feldolgozta Vas megye harasztjait és Kőszeg vidékének edényes növényeit. Érdemeket szerzett a sások ismerete terén, különösen a Carex fritschii leírásával. Adományozott növénygyűjteményével a Vasvármegyei, ma Savaria Múzeum Természettudományi Osztályának egyik alapítója (SAMU). Gyűjteményének másik része a Magyar Természettudományi Múzeum Növénytárában (BP) található.
Kárpáti, erdélyi, dácikus és pannon endemikus fajok a Szilágyság flórájában
Authors: Negrean Gavril , Karácsonyi Károly , Szatmari Paul-Marian
Published: December 2015

Az Erdélyi-medence és az alföldi pannon flóratartomány között elterülő romániai Szilágyság növénytakarójában az európai fajok mellett, a különböző földrajzi eredetű flóraelemek százalékos aránya igen magas. Ezek közül kiemeljük a keleti eredetű kontinentális, valamint a déli szubmediterrán jellegűek itteni széleskörű elterjedését. Jelentős számmal vannak képviselve az alább elemzett kárpáti (Aconitum moldavicum Hacq., Symphytum cordatum Waldst. & Kit.), erdélyi (Cephalaria radiata Griseb. & Schenk, Onosma pseudoarenaria Schur subsp. pseudoarenaria), dácikus (Helleborus purpurascens Waldst. & Kit., Phyteuma tetramerum Schur) és pannon (Centaurea sadleriana Janka), endemikus valamint szubendemikus fajok is, amelyek igen különböző jellegű termőhelyeken jelentkeznek.
ASPECTOS POLÍTICOS DA EDUCAÇÃO QUILOMBOLA: CURRÍCULO E PRÁTICA PEDAGÓGICA EM DISCUSSÃO
Authors: Santana Jaqueline
Published: December 2015

Este artigo pretende discutir rumos e caminhos para implementação da Lei 10639/03 e das Diretrizes Curriculares Nacionais para a Educação das Relações Étnicorraciais no âmbito das escolas quilombolas,  por meio do entendimento de como a cultura local, ao ser utilizada como  recurso pedagógico  interdisciplinar, pode contribuir para a construção de identidade das crianças. Para tanto, será realizada uma revisão bibliográfica que tem, como pressupostos teóricos, os estudos relativos à educação quilombola e da educação etnicorracial, assim como aqueles referentes ao papel da cultura como instrumento de construção de identidade e conquista de cidadania. Espera-se, com tal discussão, promover reflexões acerca dos quilombos e de sua importância para a sociedade brasileira, assim como fomentar novas possibilidades de trabalho educativo nesses espaços.
REFLEXÕES SOBRE A INFLUÊNCIA DO MERCADO EDITORIAL EM A MÁQUINA, DE ADRIANA FALCÃO
Authors: Chaves Mônica grisi
Published: December 2015

O presente artigo tem por objetivo proceder a uma reflexão sobre a relação estabelecida entre a prosa brasileira contemporânea e o mercado editorial. Tendo como via de acesso o romance A Máquina (1999), da escritora Adriana Falcão. Esta abordagem parte do princípio de que a leitura crítica do objeto artístico na atualidade exige a adoção de novos parâmetros e o mercado pode ser um dos indicadores, dada a sua participação no presente contexto de produção estética. Para tanto, serão acionados estudos desenvolvidos por Beatriz Rezende, Karl Erik Schollhammer e Silviano Santiago.
CONTEXTOS, CULTURA E SUBALTERNIDADE NO CINEMA BRASILEIRO CONTEMPORÂNEO
Authors: Ikeda Rodolfo Nonose
Published: December 2015

Este trabalho objetiva discutir, primeiramente, algumas questões sobre cultura e cultura popular para, posteriormente, refletir sobre os processos de (re)construção de regimes discursivos da subalternidade pelo cinema brasileiro contemporâneo nas décadas de 1990 a 2010, tendo em vista as circunstâncias de produção articuladas ao contexto sócio-histórico. O aporte teórico-crítico são os estudos culturais e os estudos sobre cinema brasileiro. Parte-se da ideia de que filmes como “Os Matadores” (BRANT, 1997), “Cidade de Deus” (MEIRELLES, 2002), “Tropa de Elite” (PADILHA, 2007), “Tropa de Elite 2” (PADILHA, 2010) e “O Som ao Redor” (MENDONÇA, 2012), (re)inventam regimes discursivos da subalternidade, fornecendo subsídios para a compreensão da cultura popular.
A RE-MITIFICAÇÃO DA HISTÓRIA DE NGUNGUNHANA EM UALALAPI, (1987) DE UNGULANI BA KA KHOSA.
Authors: Dultra Rodrigo Santos
Published: December 2015

Baseado no atual contexto das culturas afro-brasileiras e africanas este trabalho visa fazer uma análise do livro Ualalapi, lançando um olhar especial para a figura emblemática de Ngungunhana, sob a perspectiva da metaficção historiográfica, além de evidenciar a importância de se conhecer as literaturas africanas de língua portuguesa e o seu papel como difusora de uma cultura bem como o de guardiã de uma memória coletiva. Demonstrar também a importância da recontação das histórias silenciadas no período pós-independência, pois através da arte literária outras vozes puderam ser ouvidas e hoje pode-se escutar outras versões dessas mesmas histórias. As tensões entre modernidade e tradição também fazem parte da trama narrativa, que será demonstrada e analisada neste trabalho tomando como base algumas ideias de teóricos pós-coloniais.
Correlation of 30 consecutive idiopathic pulmonary fibrosis patients intertiary care center
Authors: Qureshi Asmath , Sarma Latha , Adepu Vijayalakshmi , KA Mohit Chilana
Published: December 2015

Background: Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause, primarily occurring in older adults, limited to the lungs, and associated with histological and/ or radiologic pattern of usual interstitial pneumonia. The objective of the study is to correlate severity of IPF and duration of symptoms with spirometry test/ forced vital capacity (FVC), high resolution computed tomography (HRCT) findings, smoking history, age and sex of 30 consecutive IPF patients in a tertiary care centre. Methodology: The study was done on 30 consecutive patients of IPF, clinically and radiologically fulfilling the criteria for IPF. Results: The study group showed significant male predominance of 80%. Subpleural, basal predominance, reticulations and honey-combing pattern on HRCT was seen in 100%, while traction bronchiectasis in 76.7% and minimal ground glassing in 33.3%. 23 out of 30 patients presented with symptom duration of 13-18 months, with mean duration of 16.4 months. 53.3% of the study population were smokers, 26.6% ex-smokers. Conclusion: Clinicians should integrate clinical, radiological and/ or pathological data to support the diagnosis of IPF. Smokers are at particular risk for IPF and should be watched for at every visit. As IPF evolves over a period of time, early CT chest may not have all the radiological features supporting IPF. Close follow up is therefore suggested. Keywords: Idiopathic pulmonary fibrosis; Forced vital capacity; High resolution computed tomography; Bronchiectasis
A study of Acinetobacter from various clinical specimens & its antibiotic sensitivity pattern in a tertiary care hospital
Authors: Rani Pragya , B Madhavi Latha , R Sukrutha Gopal , B Anil Kumar
Published: December 2015

Background: Acinetobacter baumannii has emerged as a significant hospital pathogen, quickly becoming resistant to commonly prescribed antimicrobials. Objectives: To isolate various species of Acinetobacter, to compare inpatients (ICU’s & wards) and outpatients isolates and to know it’s frequency from various clinical specimens. Material and methods: The retrospective study is conducted in the department of Microbiology, Krishna Institute of Medical Sciences, Secunderabad, from January 2013 to December 2014. The various clinical specimens from inpatients and outpatients were included. The samples were processed as per the standard guidelines. Identification & antibiotic sensitivity testing was done by using GN and AST 281 cards (Vitek 2 compact, BioMerieux) respectively. MIC values of antibiotics were obtained and reporting was done as per the CLSI guidelines. The data was captured from the laboratory computer and analysed. Results: A total of 496 Acinetobacter species were isolated from 2459 samples (20.17%) from the entire hospital, in which Acinetobacter baumannii was 462(93.16%), Acinetobacter lwoffii was 16(3.22%), Acinetobacter junii was 13(2.62%), Acinetobacter haemolyticus was 5(1.00%). Maximum isolates observed from endotracheal tube secretions (39.51%) followed by blood specimens (15.12%), sputum (12.70%), pus swab (8.66%), clean catch (5.84%) and others (18.17%). Conclusions: In this study, Acinetobacter isolates showed multidrug resistant pattern mostly in inpatients and hence there is a need for emphasizing the importance of hand washing and use of disinfectants in prevention of transmission of infection in health care setups. Keywords: Acinetobacter; multi-drug resistance; Acinetobacter baumannii; Acinetobacter haemolyticus; VITEK
Radiology of crystal arthropathies
Authors: Kakarla Subbarao
Published: December 2015

Not available
Clinical and genetic heterogeneity in Wilson disease - A review
Authors: Rangaraju Advithi , MS Sridhar , Naik Poonam
Published: December 2015

Wilson disease (WD) is an inborn error of copper metabolism leading to its accumulation in liver, kidney and cornea. It is caused by a defective ATPase protein which is coded by ATP7B gene. It follows an autosomal recessive mode of inheritance with a prevalence of 1 in 30,000. WD shows varied clinical heterogeneity making clinical diagnosis a difficult task. The corneal Kayser-Fleischer (KF) ring is an important diagnostic criterion as it is invariably present in 95% of the WD cases. In this review, we discussed the varied clinical manifestations of WD which makes diagnosis a challenging process. Though genetic testing is a reliable technique to confirm clinical diagnosis, genotype-phenotype correlations are yet to be established. This could be attributed to the consanguinity and ethnic variation observed in the Indian population, suggesting genetic heterogeneity leading to clinical heterogeneity making diagnosis difficult. Further, genetic studies are warranted to establish genotype-phenotype correlations which can pave way for early diagnosis and treatment. Genetic testing will help in identifying pre-symptomatic siblings and other family members of the patient who should be advised for regular follow-up. A combination of clinical and genetic studies should be considered for proper understanding of disease manifestation and for making an early clinical diagnosis of WD. Keywords: Wilson disease; copper metabolism; genetic testing; ATP7B gene; KF ring
Analysis of vitamin B12 and D deficiency and the effect of supplementation on patients at tertiary care hospital
Authors: B Srinivasa Rao , G Sakuntala Devi , K Kavitha , GVVS Kanaka Bhushanam
Published: December 2015

Vitamins are essential organic compounds for the body and the study aims to understand the extent of deficiency present among the patients tested for deficiency and the effect of supplementation. Our study also aims in understanding the effect of supplementation on treating the deficiency along with its effect on any secondary disease conditions present among the patients such as diabetes, cardiovascular disease, rheumatoid arthritis, osteoporosis and/or hypertension. Assessment was carried out in randomly selected, 500 patients from the patient pool (March 2013 to March 2015) and supplemented with vitamins at KIMS hospital, Secunderabad. Data such as biochemical measures, medications, food supplements and herbal medicines were also taken into consideration. The assessment showed improvement in deficiency symptoms after supplementation. Along with this, the improvement in general health of patients that have secondary conditions was analyzed. The study shows that patients with osteoporosis are benefited by vitamin D supplementation and supplementation seems to also helped patients with pain in case of rheumatoid arthritis. Patients with diabetes and/or cardiovascular disease did not show much improvement with supplementation. Patients with hypertension solely or with other conditions show improvement with this problem compared to other conditions. We observed that supplementation does have a role in general health improvement in patients with some chronic conditions. Keywords: vitamin D; vitamin B12; deficiency; general health; supplementation
Socio-emotional selectivity in elderly and old age as a factor of subjective well-being
Authors: Melehin A.
Published: December 2015

The article shows that the presence of social support, сonfidant network is associated with positive subjective well-being in elderly (55 - 74 years) and old age (75-90 years). However, certain types of social interaction can be considered as predictors of affective disorders and chronic somatic disorders in later ages as in normal aging and in neurodegenerative disorders. The purpose of this article is to familiarize professionals in the mental health of people of later ages with the theory of socio-emotional selectivity (Socioemotional Selectivity Theory) L.L. Carstensen, who makes a significant contribution to the understanding of the specificity and mechanisms of selection in social interaction in elderly and old age. Central mechanisms of socio-emotional selection in the later ages are the awareness of time and limited future time perspective, which enhances the awareness of mortality.
Alexithymia in persons regularly engaged in wellness yoga
Authors: Ledovskikh A.G. , Lukovtseva Z.V.
Published: December 2015

The aim of the study was to describe qualitative-quantitative characteristics of alexithymia in persons regularly engaged in Wellness yoga. The study involved 62 adult subjects, grouped into two groups. The main group included people practicing Hatha yoga and Iyengar yoga, the control group included people who are not engaged in sports activities. Methodical complex amounted tools for diagnosing the level of alexithymia and related emotional and personal characteristics. There was no statistically significant difference in the level of alexithymia between the examined groups, however, the descriptive statistics and the results of a qualitative analysis of the data indicate the presence of qualitative-quantitative specifics of the alexithymic symptoms in people practicing yoga.
Psychological support for mothers of children with autism spectrum disorders via traditional Russian tea party
Authors: Belopolskaya N.L. , Ruban O.V.
Published: December 2015

The study aimed to discuss the possibility of providing psychological support for mothers of children with autism spectrum disorders via traditional Russian tea party. Questionnaire results, according to which mothers of children with ASD are essentially focused on receiving psychological counseling in the area of child development and education are presented. However personal problems of the woman, including psychological weightiness is usually taken a back seat. The research supports a hypothesis that informal format of tea party allows mothers decreasing psychological distance with psychologist, feeling at ease. The article includes an analysis of psychological meetings focused on personal life questions of participants. The results obtained in the research showed effectiveness of this approach. The Russian tea party is a meeting form that fosters the growth of confidence toward psychologist, expanding the range of personal questions that could be discussed. The mothers had the opportunity of open communication with each other, reported psychological safety valve.
5th World Congress on ADHD: From Child to Adult Disorder
Authors: Goryacheva T. , Sedova E.O.
Published: December 2015

The article concerns the 5th World ADHD Congress, organized by the World Federation of ADHD in May 2015. It informs about the lectures, symposia and discussions of diagnostics and differential diagnostics of ADHD, as well as issues, concerning intervention programs.
Jubilee of N.V. Zvereva
Authors: Roschina I.
Published: December 2015

In the second part of November 2015 well-known domestic clinical psychologist Natalia Zvereva celebrates her Jubilee. Natalia Zvereva is a professor of the department of neuro- and patho- psychology of development of Moscow state university of psychology and education, leading researcher of department of medical psychology of Mental health research center.
Turmeric (Curcuma longa): From a Variety of Traditional Medicinal Applications to its Novel Roles as Active Antioxidant, Anti-Inflammatory, Anti-Cancer and Anti-Diabetes
Authors: Hamidpour Rafie , Hamidpour Soheila , Hamidpour Mohsen , Sohraby Mahnaz , Hamidpour Roxanna
Published: December 2015

Curcumin l
onga, which is commonly known as Turmeric, is an herbaceous perennial plant from the Curcuma genus that prospers in mainly Eastern Asia. Through a series of forms including powder and extract, the plant has been traditionally used to assist in inflammation and wound healing. Turmeric has been shown to alleviate the pain of inflammation in diseases such as rheumatoid arthritis and psoriasis, overall promoting the immune system response of acute inflammation for its therapeutic abilities and alleviating chronic inflammation. Not only has it been shown to assist in inflammation, but Turmeric has been shown to assist in preventing and battling cancer through its cytotoxic activities while boosting apoptosis to control the growth and distribution of cells. Along with these abilities, this plant assists with the pain and inflammation involved with diabetes. Turmeric is able to do this because of it being largely composed of a substance called Curcumin, a mixture of Turmeric oil and resin.
Dynamics of Interleukin-10 Levels in Chronic Rhinosinusitis with/without Allergy
Authors: Punagi Abdul Qadar , Rahardjo Sutji Pratiwi
Published: December 2015

BACKGROUND: Rhinosinusitis occurs when the lining of the nasal and sinuses gets inflamed, infected or irritated, become swollen, and create extra mucus, the swollen lining may also interfere with drainage of mucus. Chronic rhinosinusitis (CRS) is a more persistent problem that requires a specific treatment approach. Aim of this study was to determine changes in interleukin (IL)-10 as an anti-inflammatory cytokines in allergic and non-allergic CRS at Makassar. METHODS: A prospective cohort study was designed to assess the level of IL-10 for three times during two weeks of therapy. Medication of Cefadroxil 500 mg 2x1, Pseudoephedrine 30 mg 2x1, Terfenadine 40 mg 2x1 and Methylprednisolone 4 mg 3x1, was conducted during two weeks for 13 subjects in allergic CRS group and 12 subjects in non-allergic CRS group. Results were statistically analyzed with student t-test and paired t-test.RESULTS: The changes in levels of IL-10 in allergic CRS group were increased, but not significant (5.293 to 5.769, p=0.058), and in non-allergic CRS group were decreased, but not significant (6.125 to 5.475, p=0.103). CONCLUSION: The serum levels of IL-10 were not significant increased in allergic CRS group and not significant decreased in non-allergic CRS group. KEYWORDS: interleukin-10, chronic rhinosinusitis, allergy, cefadroxil, pseudoephedrine, terfenadine, methylprednisolone
Propofol Effect on Stress Response and Free Radicals in Patient during Surgery and Sedation Procedure
Authors: Rahardjo Theresia Monica
Published: December 2015

BACKGROUND: Propofol is an intravenous anesthetic used worldwide as an anesthesia induction and maintenance agent. Propofol also used as sedation agent in Intensive Care Unit (ICU). Despite it’s usual anesthesia properties, propofol has an unique pharmacologic characteristic, especially as antioxidant and stress response reduction. These advantages suggested propofol has positive effects when used as an anesthesia agent in surgery or sedation in ICU in conditions when high stress and free radical level are released.CONTENT:Stress response and free radical can be elevated in various conditions including surgery or during care in ICU, especially critical ill patient. Cortisol is a major stress hormone that influences metabolism, cardiovascular and central nervous system, either in acute or chronic phase. Oxidative stress was marked by free radical elevation called Radical Oxygen Species (ROS). Combination of both elements (cortisol and ROS) can worsen patient condition. Propofol with anti-stress and antioxidant properties could be used to reduce stress response and attenuate free radical level in order to improve patient condition.SUMMARY: The anti-stress and antioxidant properties of Propofol are interesting, because these benefits can be added as adjunctive therapy when propofol was used as an anesthetic agent in surgery and a sedation in ICU.KEYWORDS: propofol, stress response, antioxidant
Morbilidad materna extrema en la Clínica Universitaria Colombia, Bogotá (Colombia), 2012-2013
Authors: Villalba-Toquica Carolina Del Pilar , Martínez-Silva Pablo Andrés
Published: December 2015

Objetivo: describir la morbilidad materna extrema en una clínica de alta complejidad obstétrica.

Materiales y métodos: estudio descriptivo de vigilancia epidemiológica, basado en el análisis de los resultados de la implementación del subsistema de vigilancia de la morbilidad materna extrema (MME) en la Clínica Universitaria Colombia, entre junio de 2012 y junio de 2013. Esta es una institución de referencia que atiende pacientes de una empresa de aseguramiento privado y contributivo en Bogotá. Se estableció el número de gestantes que presentó morbilidad materna extrema en dicho periodo. Se evaluó la edad materna, la situación de salud generadora del reporte, los criterios definitorios de MME y los indicadores de calidad de la MME. Se realiza análisis descriptivo de los datos y se presenta la razón de prevalencia de la morbilidad materna extrema.

Resultados: la prevalencia de MME en la institución fue de 11 por 1.000 nacidos vivos. El 55 % de los eventos se relacionaron con hemorragias del embarazo, seguidos por trastornos hipertensivos del embarazo (30 %), complicaciones de comorbilidades cardiacas (9 %) y choque séptico (6 %). Un 58 % de las pacientes presentaron disfunción orgánica, con una utilización de la Unidades de Cuidado Intensivo en 52 %; la transfusión de hemoderivados se requirió en un 61 % de los eventos y la cirugía adicional en un 36 %. El índice de mortalidad fue del 8 %. La relación MME/MM fue de 11:1. El porcentaje de casos de MME con más de tres criterios fue del 73 %.

Conclusión: la morbilidad materna extrema es un problema frecuente en esta institución de referencia. Su medición es posible con base en la vigilancia pasiva y activa de los criterios definitorios. Se requiere más información de estos indicadores de calidad a nivel nacional para hacer comparaciones entre instituciones.
Factores de riesgo asociados al desarrollo de pielonefritis aguda entre las gestantes afiliadas a una Empresa Administradora de Planes de Beneficio en cuatro ciudades de Colombia. Estudio de casos y controles
Authors: López-Martínez Jessika Lissethe , Montoya-Jaramillo Yanett Marcela , Berbesi-Fernández Dedsy Yajaira
Published: December 2015

Objetivo: identificar factores de riesgo relacionados con pielonefritis aguda durante la gestación en las gestantes de Barranquilla, Bogotá, Bucaramanga, Cali y Medellín (Colombia), afiliadas a una empresa administradora de planes de beneficio.

Materiales y métodos: estudio de casos y controles, con dos controles por caso. Criterios de selección: gestantes que presentaron parto entre el 1 de enero de 2008 y 31 de diciembre de 2012, en las diferentes instituciones prestadoras de servicios de salud de una empresa administradora de planes de beneficio en Colombia; se excluyeron aquellas con anomalías del tracto urinario. Se definieron como caso aquellas que tenían diagnóstico de pielonefritis aguda durante el embarazo, y como control las gestantes con parto atendido en el mismo periodo, sin diagnóstico de pielonefritis. Los casos fueron seleccionados por conveniencia de manera consecutiva, los controles de manera aleatoria. Se midieron las variables gestacionales, sociodemográficas y las comorbilidades. Se evaluó la asociación con análisis bivariado y multivariado.

Resultados: se halló una incidencia de 18 casos de pielonefritis por 10.000 gestantes. El diagnóstico se realizó entre la semana 5 y 38 de gestación, la mayoría durante el segundo (40,2 %) y tercer (48,0 %) trimestre. Ningún caso presentó antecedentes de pielonefritis. Se halló asociación entre pielonefritis aguda y primigestante (OR = 1,94; IC 95 %: 1,13- 3,33), adolescente (OR = 2,85 ; IC 95 %: 1,51-5,40) e infección del tracto urinario previa al embarazo (OR = 2,29; IC 95 %: 1,17-4,44).

Conclusión: ser primigestante, adolescente y con antecedente de infección baja del tracto urinario previa al embarazo son factores de riesgo para pielonefritis aguda gestacional.
Sulfato de magnesio para neuroprotección fetal: revisión de la literatura
Authors: Muñoz-Martínez Camilo , Parra-Pineda Mario Orlando
Published: December 2015

Objetivo: revisar la evidencia disponible acerca de la efectividad y seguridad del sulfato de magnesio como neuroprotector en fetos pretérmino.

Materiales y métodos: se realizó una búsqueda de la literatura en las bases de datos, Medline, SciELO, Embase y ScienceDirect y Cochrane, utilizando los términos de búsqueda: "premature birth, cerebral palsy, magnesium sulfate", restringida a los siguientes tipos de estudios: metaanálisis, revisiones sistemáticas, guías de práctica clínica y ensayos clínicos controlados, entre el 2000 y el 2013.

Resultados: la búsqueda en las bases de datos electrónicas arrojó 31 títulos, de los cuales se excluyeron 19 estudios debido a que no respondían a la pregunta inicial, eran artículos de revisión narrativa, doble publicación, incluían estudios observacionales o se trataba de protocolos de investigación. Finalmente, se seleccionaron 12 artículos que corresponden a 5 revisiones sistemáticas, 5 ensayos clínicos controlados y 2 guías de práctica clínica. El sulfato de magnesio disminuye el riesgo de parálisis cerebral en alrededor del 30 % y de disfunción motora gruesa en un 40 %. No tiene impacto significativo en otros desenlaces como mortalidad perinatal, leucomalacia periventricular o hemorragia intraventricular. Este efecto protector es mayor en edades gestacionales más tempranas. Los eventos adversos maternos y neonatales son generalmente leves.

Conclusiones: el sulfato de magnesio utilizado en pacientes con trabajo de parto pretérmino, fase activa antes de semana 32, es un tratamiento efectivo y seguro en la prevención de la parálisis cerebral en fetos prematuros.
Resucitación cardiopulmonar y cerebral en la embarazada. Al final del colapso materno
Authors: Vasco-Ramírez Mauricio
Published: December 2015

Objetivo: proporcionar a los profesionales de la salud involucrados en el manejo de gestantes con complicaciones (obstetras, enfermeras, médicos generales y de emergencias, anestesiólogos, intensivistas, entre otros) los principios fundamentales de prevención y manejo de paro cardiorrespiratorio (PCR) en este grupo poblacional con el fin de mejorar los resultados del binomio madre-hijo.

Materiales y métodos: el documento se basa en una búsqueda de publicaciones en las bases de datos Medline, SciELO y Embase utilizando los términos "Cardiopulmonary Resuscitation, Pregnancy, Perimortem Cesarean, Maternal Cardiac Arrest, Cardiac arrest in pregnancy", y restringida a los siguientes tipos de publicación: "Meta Analysis, Systematic Reviews, Practice Guideline, Randomized Controlled Trial, Review, Case Report, Chapter, Editorial, Survey".

Resultados: se encontraron 78 títulos de los cuales se incluyeron 63; de estos, 22 corresponden a revisiones narrativas, 20 a reportes y series de caso, 8 a guías de práctica clínica, 5 a ensayos clínicos, 4 editoriales, 2 corresponden a revisiones sistemáticas o metaanálisis, 1 capítulo de libro y 1 encuesta o survey.

Conclusiones: el paro cardiaco en gestantes impone un reto al grupo interdisciplinario que lo enfrenta, por ser una entidad de baja frecuencia que se puede asociar a un alto grado de morbimortalidad materna y perinatal. Las principales acciones por realizar son: activación del código azul obstétrico con respuesta adecuada para realización de histerotomía de emergencia oportuna, compresiones torácicas de buena calidad, desviación manual uterina 15º a la izquierda cuando el útero grávido se palpe por encima del ombligo materno, manejo avanzado farmacológico y de vía aérea, y cuidado óptimo luego de la resucitación para la madre y el neonato.
Pentalogía de Cantrell y bandas amnióticas: reporte de un caso y revisión de la literatura
Authors: Saldarriaga-Gil Wilmar , Ayala-Zapata Sebastián , Ramírez-Cheyne Julián Andrés , Isaza Carolina
Published: December 2015

Objetivo: reportar un caso de pentalogía de Cantrell asociado a acranea, hendidura facial medial y reducción de las extremidades derechas originado por bandas amnióticas. Realizar una revisión de la literatura sobre la patogénesis de las bandas amnióticas y los hallazgos en el caso reportado.

Materiales y métodos: se presenta el caso de un recién nacido muerto, con malformaciones congénitas antes mencionadas, hijo de madre primigestante de 15 años con 34 semanas de gestación, que consultó al Hospital Universitario del Valle (HUV), hospital de nivel III y IV de referencia en obstetricia, de la red pública del suroccidente colombiano. Como fuente de información se utilizó la historia clínica, fotografías del recién nacido y los Rayos X.

Se realizó una búsqueda de literatura con las palabras clave "Pentalogy of Cantrell and amniotic band syndrome", "Limb body wall complex and amniotic band syndrome" en las bases de datos Medline vía PubMed en inglés y español, sin límite de tiempo; se buscaron reportes de caso, revisiones de tema y series de casos.

Resultados: se encontraron treinta artículos, se analizaron todas las referencias y se halló que catorce corresponden a reportes de caso, ocho a revisiones de tema y ocho a series de casos.

Conclusiones: se reporta un caso de pentalogía de Cantrell, posiblemente por bandas amnióticas originadas en el desarrollo embrionario. El caso se clasificó como complejo cuerpo-extremidad (LBWC), secundario a bandas amnióticas.
Conocimientos y prácticas de los jóvenes respecto a la Infección por el Papiloma Virus Humano - una cuestión reactualizada
Authors: Sepúlveda-Carrillo Gloria Judith , Goldenberg Paulette
Published: December 2015

Introduction: Because of the size of the problem and the implications for triggering several forms of cancer such as cervical cancer, the human papilloma virus (HPV) is considered a public health issue.

Objective: The purpose of the study was to conduct a systematic review of the literature on sexuality, knowledge, preventive practices and vulnerability in relation to HPV infections among adolescents and young adults.

Materials and methods: Bibliographic searches in journals and/or scientific periodicals with serialized publications indexed in the Bireme, PubMed, ScienceDirect, SpringerLink and Scopus databases, during the period between 1995 and 2012.

Results: In total, 60 articles were selected, including 36 reviews, 17 cross-sectional studies, 2 cohort studies, 2 case-controls studies, 1 clinical trial, 1 qualitative study, and 1 case series. A significant proportion of the youths showed a limited perception not only of the forms of transmission but also of the consequences of the infection, and gender differences were noteworthy. As they fail to identify the personal risk of catching the infection, youths forgo the use of protection such as practicing safe sex in cases of stable or non-stable relationships, as well as in heterosexual and homosexual forms of intercourse.

Conclusions: The study showed evidence of the need to implement specific interventions for HVP focused on the youth, under the conceptual perspective of vulnerability.
Frecuencia de solicitud y prevalencia de reactividad de la prueba no treponémica (VDRL) en pacientes con aborto en el Hospital Local del Norte de Bucaramanga, Colombia
Authors: Ortiz-Serrano Ricardo , Herrera-Galindo Víctor Mauricio , Acuña-Padilla Catalina
Published: December 2015

Introducción: la adherencia a las recomendaciones para la tamización de sífilis en mujeres gestantes es fundamental en la prevención de lúes congénita. El objetivo de este estudio fue estimar la frecuencia de solicitud de prueba no treponémica y reactividad en mujeres que cursan con aborto.

Materiales y métodos: estudio de corte transversal basado en el registro de pacientes que atendieron a la consulta de urgencias de obstetricia del Hospital Local del Norte de Bucaramanga entre enero 1º y diciembre 31 de 2011, y que tuvieron un diagnóstico de aborto. En estas pacientes se determinó la prevalencia de solicitud de la prueba no treponémica (VDRL), así como de resultados reactivos.

Resultados: en el periodo de estudio se identificaron 233 mujeres con diagnóstico confirmado de aborto. La edad promedio fue de 24,2 ± 7,3 años, con una edad gestacional de 9,1 ± 3,3 semanas. Se documentó evidencia de solicitud de prueba no treponémica en 135 pacientes (57,9%; IC 95%: 51,6-64,3) de las cuales 5 (3,7%; IC 95%: 0,5-6,9) tuvieron resultados reactivos: 1 con títulos de 1:2; 3 con títulos de 1:4, y 1 con títulos de 1:32.

Conclusión: pese a las recomendaciones vigentes, la prevalencia de solicitud de prueba no treponémica en pacientes con aborto es baja. Lo anterior evidencia la necesidad de concientizar al personal de salud acerca de la importancia de cumplir a cabalidad el protocolo de atención a la gestante.
Vasa previa, presentación de un caso en un centro de referencia en Envigado, Colombia, y revisión de la literatura
Authors: Bonilla-Sepúlveda Óscar Alejandro
Published: December 2015

Objetivo: reportar un caso de vasa previa y hacer una revisión de la literatura en cuanto a la patogénesis, el diagnóstico ecográfico antenatal y el pronóstico perinatal de la misma.

Materiales y métodos: se presenta el caso de una paciente de 44 años de edad y 36 semanas de gestación, que consultó al Hospital Manuel Uribe Ángel (HMUA), institución pública de segundo nivel de atención, centro de referencia obstétrica ubicado en el municipio de Envigado, Antioquia. Se utilizó como fuente de información la historia clínica, se realizó una búsqueda de literatura con las palabras clave“vasa previa”, “ultrasonography”, “prognosis” en las bases de datos Medline vía PubMed de los años 1993 a 2013 en inglés y español; se buscaron revisiones de tema, revisiones sistemáticas y reportes de caso.

Resultados: se encontraron 35 artículos, se analizaron todas las referencias y se halló que 22 corresponden a reportes de caso, 8 a revisiones de tema y 5 a revisiones sistemáticas.

Conclusiones: la vasa previa es una complicación obstétrica poco frecuente. La evaluación de la placenta por ultrasonido es un método útil para determinar la inserción del cordón umbilical y sus posibles anormalidades. El pronóstico es pobre, con altos índices de mortalidad fetal si no se realiza un diagnóstico antenatal.
El control judicial del contencioso administrativo en servicios públicos
Authors: Vargas Ayala Guillermo
Published: December 2015

No hay dudas de la importancia constitucional que supone el control judicial de la jurisdicción de lo contencioso en materia de servicios públicos. Aprovechando la conmemoración de los 20 años de la Ley de los Servicios Públicos Domiciliarios –Ley 142 de 1994–, este artículo invita a la reflexión sobre la realidad del derecho de los servicios públicos. Luego de una detallada exposición de algunos antecedentes de la jurisdicción de lo contencioso, se expone lo que aquí se denomina zonas de certeza y zonas de incertidumbre competencial del contencioso administrativo en materia de servicios públicos. Al realizar un análisis detallado de la jurisprudencia del Consejo de Estado, se llega a la inevitable conclusión de que la extensión del control contencioso sobre los actos de las autoridades y de los operadores del sector es mucho más amplio de lo que inicialmente se pensó. El administrativo se resiste a dejar de ser el derecho de los servicios públicos y el contencioso persiste en ser el juez del interés general y de las prerrogativas públicas.
The road towards the harmonisation of trade secrets law in the European Union
Authors: Torremans Paul L. C.
Published: December 2015

Trade secrets have traditionally been protected in various ways by national laws in the European Union. The international intellectual property treaties offered only a limited common core. From this starting point this article examines the new EU draft directive on trade secrets. The aim is not to put in place a comprehensive EU regime for the protection of trade secrets. There will only be a partial harmonisation of the national laws of the Member States, focussing on the unlawful acquisition, disclosure and use of trade secrets, and that harmonization will be of a minimalist nature in the sense that Member States may provide, in compliance with the provisions of the Treaty, for more far-reaching protection against the unlawful acquisition, use or disclosure of trade secrets than that required in the Directive.