bluuebunny/crossref_metadata_2025 huggingface dataset:
JILBER’S SYNDROME: CLINICAL AND PHARMACOLOGICAL ASPECTS. Review
Authors: Khaitovych M.V. , Turchak D.V.
Published: January 2021

Relevance. At present, the metabolism of drugs in patients with Gilbert's syndrome will be actively studied, as it may be associated with both the risk of dose-dependent adverse reactions and treatment ineffectiveness.
Objective: to summarize the information of various authors on the peculiarities of the use of drugs in patients with Gilbert's syndrome.
Methods. Analysis of scientific publications in the international electronic scientometric database PubMed by keywords. Search depth - 10 years (2010-2019).
Results. Gilbert’s syndrome is observed in 3-10% of the population and is characterized by an isolated increase of bilirubin in the blood to moderate values without changes in other biochemical parameters of liver function and without damage to its structure. Gilbert's syndrome is inherited autosomal recessively and is mainly due to the presence of an additional dinucleotide thymine-adenine (TA) in the promoter region A(TA)6TAA gene encoding the enzyme UGT1A1. Elongation of the promoter sequence reduces the formation of UGT1A1. Invariant A(TA)7TAA, the level of enzyme production can be reduced to 80% of the norm in hetero- and up to 20% in homozygotes, respectively. Gilbert’s syndrome is manifested by increased levels of indirect bilirubin in the blood, jaundice of the skin and mucous, abdominal pain, as well as dyspepsia, and asthenovegetative syndrome. Intermittent icteric sclera and skin occur against the background of exogenous and endogenous factors such as starvation, dehydration, infectious diseases, emotional and physical stress, hemolysis, menstruation, alcohol consumption, hormonal contraception, etc., usually at a bilirubin concentration exceeding 40-45 μmol/l. Complications of hyperbilirubinemia with Gilbert’s syndrome include the development of gallstone disease, including in children and adolescents. Gilbert’s syndrome is associated with impaired metabolism of some drugs – aglucones. These include anabolic steroids, glucocorticoids, androgens, rifampicin, cimetidine, chloramphenicol, streptomycin, sodium salicylate, ampicillin, caffeine, Ethinyl estradiol, paracetamol, ibuprofen, The clinical feature of Gilbert’s syndrome is the appearance or aggravation of jaundice associated with the use of such drugs. In conditions of UGT1 deficiency, drugs compete with bilirubin for the enzyme, which leads to an increase of indirect bilirubin in the serum. Therefore, to prevent liver damage, it is necessary to assess the risk and benefit of drug treatment of patients with Gilbert’s syndrome in each case.
Conclusions. Gilbert’s syndrome is a common pathological condition and therefore it is important to diagnose it as early as possible. Given that the use of aglucones in patients with Gilbert's syndrome may cause the development of drug-induced liver damage, it is necessary to assess the risk and benefit of drug treatment of patients with Gilbert’s syndrome in each case.
QUALIFICATION REQUIREMENTS FOR INDIVIDUALS AND ORGANIZATIONS WHICH CONDUCT THE AUDIT ON CIVIL PROTECTION, TECHNOGENIC AND FIRE SAFETY
Authors: Havrys A. , Sukach Yu.
Published: January 2021

Introduction. In this study, the problem of audit concept definition scarcity in legal documents (expert assessment) of civil protection, technological, and fire safety was considered. Specific qualification requirements, structure, rights, respon-sibilities, reports, a system for conducting and results registration of auditor inspections and audit organizations working in civil protection field and fire safety inspection have not been approved.Today, the issue of audit (expert assessment) of civil protection, technological, fire safety, and insurance of facilities is becoming the most pressing issue. Society, and in particular businesses, are reorienting themselves to European standards of doing business, where property insurance is necessary, and it guarantees them compensation in the case of an emergency.Purpose. The main purpose of the article is to highlight the problem of the lack of a rightful audit concept in civil protection, technological, and fire safety.Methods. Expert assessment of the state of businesses, institutions, and organizations, regardless of their ownership form, makes it possible to get a full picture of object shortcomings, proposals for their elimination, without prosecuting officials quickly and efficiently and without terminating the installation, units and the object as a whole. The audit is a kind of state supervision (control) in the field of civil protection, technological, and fire safety, but without administrative and legal consequences. Based on legal documents analysis in the field of civil protection and fire safety, processing of auditors' feedback, and practical experience of the authors of the article, the main scientific results are proposed.Results. The authors show organizational structure of audit associations. Also, the authors’ qualification requirements for auditors (experts) and their assistants, including the availability of relevant education, experience in practical, teaching, and research work in the field of civil security, and passing the qualifying examination was proposed.Conclusion. According to this organizational structure, high-class auditors create an association that will determine (organize) the activities of all levels of experts. The next step is the high-class experts, who form the relevant associations on a territorial basis, which control the activities of the first and second class experts. The last step is the first and second class auditors, who report to the higher class auditors in their activities.The proposed results should be taken into account in the existing regulations on auditing or a separate regulation in the field of civil protection, technological, and fire safety.
LEGO-LEGO AS PHENOMENON OF INTER-RELIGIOS AND CULTURAL IN ALOR SOCIETY
Authors: Iswanto Iswanto Iswanto
Published: January 2021

The reality of culture is actualised in sistemic sign relation, forming perception, representing contexts, and at the highest level it functions as a portrayal of the society’s ideology (Soames, 2010). As a phenomenon, Lego-lego defines the ideology among the people of Alor. The population live in the Island of Alor and Pantar, with Kalabahi as its capital city. There are 42 indigenous languages in the area of 2864 Km² with 66.4% of the population are Protestants, 30.27% are Muslims, 3.2% are Catholics, 0.02% are Hindus, and 0.01% are Buddhists. The primary data used was the text of Lego-lego and the secondary data was the interview trascript. The theory of Dichotomy Semiotic of Ferdinand de Saussure (1993) was used.  A descriptive qualitative method was used with a phenomenology approach (Gallagher, 2008). The result shows a) the sign system of inter-religious and culture in Lego-lego is divided into textual and intertextual signify where signify covers place and time as well as Alorese perception; b) diagram of cultural events in Lego-lego consists of group ideology, attitude, cultural events and contexts. It also shows that religion context is placed in the group attitude. To summarize, the interreligious and culture concept in Lego-lego are defined by using sign system and diagram of cultural events. Religion concept in Alor has become part of group attitude which is based on culture and perceived through Lego-lego discourse. Novelty in this research is the Alorese culture reflected in Lego-lego has become an extremely strong fundamental with inter-religious as one of its elements.
EFEKTIVITAS PENYULUH BP4 DALAM MENEKAN ANGKA PERCERAIAN DI KOTA MAKASSAR
Authors: Darmawati Darmawati , Haddade Hasyim
Published: January 2021

Penelitian ini berjudul “Efektivitas Penyuluh BP4 dalam Menekan Angka Perceraian di Kota Makassar” Masalah penelitian adalah apa faktor penyebab terjadinya perceraian di Kota Makassar? dan bagaimana bentuk upaya penyuluh BP4 dalam menurunkan angka perceraian di Kota Makassar? Jenis penelitian adalah penelitian kualitatif dengan menghasilkan data deskriptif. Penelitian dilakukan pada lima KUA di Kota Makassar. Teknik analisis data deskriptif-kritis. Informan kunci adalah kepala KUA dan para penyuluh BP4. Hasil Penelitian menunjukkan Sebab terjadinya perceraian di Kota Makassar, adalah kurangnya tanggung jawab bagi suami terhadap hal nafkah, kekerasan dalam rumah tangga, serta perselingkuhan disebabkan media sosial. Penyuluh BP4 telah melaksanakan tugas dan fungsinya secara maksimal, namun masih kadang mendapat kendala, terutama dari segi waktu, calon pengantin yang tidak sempat hadir dalam kegiatan suscatin (kursus calon pengantin), juga kendala dari segi anggaran dalam pelaksanaan penyuluhan. Kendala lainnya yang dialami oleh penyuluh dalam menekan angka perceraian adalah tidak hadirnya para pasangan suami istri yang ingin bercerai, yang seharusnya mereka datang ke kantor KUA setempat untuk mendapatkan penasihatan. Sehingga secara umum efektivitas penyuluh BP4 dalam menekan angka perceraian di Kota Makassar masih kurang maksimal.
Development and Validation of a Well-being Scale Based on Nahj al-Balagha
Authors:   Department of Counseling, Faculty of Humanities, University of Hormozgan, Bandar Abbas, Iran., Mirzaei Samira , Najarpourian Samaneh ,   Department of Counseling, Faculty of Humanities, University of Hormozgan, Bandar Abbas, Iran., Na’imi Ebrahim ,   Department of Counseling, Faculty of Psychology, Allameh Tabatabaei University, Tehran, Iran., Samavi Seyed Abdolvahab ,   Department of Educational Sciences, Faculty of Humanities, University of Hormozgan, Bandar Abbas, Iran.
Published: January 2021

Background: This study aimed to develop and validate a well-being questionnaire based on the wisdom of Nahj al-Balagha. Methods: The method of this research was descriptive. Accordingly, based on a predefined psychological well-being model, 74 items were formulated and approved by three experts from the Nahj al-Balagha field. The statistical population of this study included all adults aged 20 to 50 years, in Tehran. Using a simple sampling method, 200 people were selected as the study sample. Also, the reliability of the questionnaire was calculated through the Cronbach alpha coefficient. The validity of the questionnaire was assessed in two ways: validity and construct validity. The correlation of the questionnaire with the Ryff questionnaire was obtained for the validity of the questionnaire, and a confirmatory factor analysis was used to evaluate the construct validity. Results: The data were analyzed using the SPSS and Amos software. The results showed that the psychological well-being questionnaire had an appropriate internal consistency in the range of 0.62 to 0.85 for the subscales and 0.95 for the total scale. Also, the total score of the researcher-made questionnaire was significantly correlated with the Ryff 53-item questionnaire, using the Pearson correlation coefficient. Moreover, the fitness indices obtained from confirmatory factor analysis showed a proper construct validity for the scale; most of the items had a factor load of above 30. Conclusion: The questionnaire indicated good psychometric properties for assessing psychological well-being in Iranian society.
The Effect of an Eight-week Pilates Training on Interleukine-18 Level, Fatigue, and Balance in Women With Multiple Sclerosis
Authors:   Department of Physical Education and Sport Science, Khorasgan Branch, Islamic Azad University, Isfahan, Iran., Asvar Soodabeh , Taghian Farzaneh ,   Department of Physical Education and Sport Science, Khorasgan Branch, Islamic Azad University, Isfahan, Iran.
Published: January 2021

Background: Proinflammatory cytokines increasingly cause inflammation in patients with Multiple Sclerosis (MS). In this regard, the current study aimed to shed light on the effectiveness of an eight-week Pilates training program in the level of interleukin-18, the severity of fatigue, balance, and physical disability, in females with MS. Methods: This study was a quasi-experimental research with a pre-test-post-test design and a control group and conducted in Sirjan City, Iran. A total of 30 female MS patients (Mean±SD age: 30.15±6.97 years; 2≤ expanded disability status scale≤5.5) were selected using a purposeful sampling method and divided into control and experimental groups. The experimental group conducted the Pilates exercises for eight weeks, three sessions per week (lasting 45-60 minutes), while the control group had no regular physical activity. Before and after the training program, we evaluated fatigue, physical disability, and balance using the fatigue severity scale, the expanded disability status scale, and the Berg balance scale, respectively. Also, 5 mL of blood was taken from each participant to evaluate the interleukin-18 level. Then, the independent t-test was used to compare the pretest-posttest scores. Results: The findings indicated that the Pilates training program significantly decreased the level of interleukin-18, the severity of fatigue, and the score of physical disability (P≤0.05), and increased the balance (P≤0.05), in females with MS. Conclusion: Therefore, patients with MS can make the best use of such exercises to strengthen their immune systems and performances.
ORGANIZATION OF FOREIGN LANGUAGES DISTANCE LEARNING COURSE AT HIGH SCHOOL
Authors: I.I. Denysenko , A.M. Tarasiuk
Published: January 2021

The article is devoted to one of the advanced formats of foreign language teaching at high school, which effectively complements extramural and full-time forms of education – distance learning. The author emphasizes that the quality and effectiveness of foreign languages distance learning athigher educational establishments depends on effectively organized course; the pedagogical skills of teachers, participating in the educational process; the quality of applied methodical content.The main principles of foreign languages distance learning in higher education has been covered, the means of improving the quality and effectiveness of this educational format has been proposed, the key conceptual regulations of foreign languages distance learning has been determined. The article proposes a model for organizing foreign languages distance learning course for future specialists, describes a system to control and monitor the knowledge of all types of speech activities. It is also noted that independent work in the foreign languages distance course at high school should not be passive, but on the contrary, the student should be involved in active cognitive activities, not limited to acquiring foreign language skills, but necessarily includes their practical application; to solve certain communicative tasks in the future professional activity.The article concludes that in the process of organizing the foreign language distance learning course at high school, it is necessary to take into account not only the didactic characteristics and functions of multimedia and telecommunications as a technological basis, but also the conceptual trends of didactic distance learning as a component of modern education. In addition, it is necessary to take into account the specific nature of foreign language teaching in general.Key words: higher educational establishment, distance learning, multimedia means, independent work, information and communicative technologies, Internet, interactive engagement.
HUBUNGAN TINGKAT STRES DENGAN SIKLUS MENSTRUASI PADA SISWI KELAS XII SMA N 5 KOTA BENGKULU
Authors: Novriani Febby
Published: January 2021

Adolescence period is an important period in the life span of adolescents when theyare experiencing a transitional period of individual in finding into adulthood. The early years ofmenstruation are the period that susceptible to disturbance, 75% of women in adolescent havesustain disorder with menstruation that is irregular menstruation. The purpose of this study was todetermine the correlation between stress and we menstrual cycle in female students of XII classesat SMA N 5 Bengkulu City 2014. The study design that used was Descriptive Analytic design byusing cross sectional, population in this study were all female students of class XII consist of 106people, technique sampling used total sampling. Data Analysis were univariate and bivariate. Theresults showed that almost all respondents (84.2%) have irregular menstrual patterns. The resultsof the chi square expressed the relationship and stress levels and the menstrual cycle (p = 0.000)It is recommended to the school as a place of education for girls, school is expected to assist thestudent information about how to prevent the occurrence of stress, arrenge schedule with considencein getting relax and rest time for girls student do not that student does not feel burdenedwith activities and school schedules both in academic and non-academic, to reduce the risk ofstress on the students.
PENGARUH PEMBERIAN PENDIDIKAN KESEHATAN MOBILISASI DINI DENGAN LAMA HARI RAWAT PADA PASIEN POST OPERASI SECTIO CAESARIA
Authors: Mariati Mariati
Published: January 2021

Sectio Caesaria (SC) is a surgery to birth a child through an incision in theabdomen wall and uterus. The incidence of SC in Indonesia according to National SurveyData on 2007 is 22,8%. The labor case of SC in M.Yunus Hospital Bengkulu on 2011 is51,51%. 48,61% on 2012 and 47,84% on 2013. Childbirth by SC is not save alternativebecause it need special supervision of indication for SC. It need intensive monitoring untilmother indicated healthy, one of effort is Early ambulation as a wisdom for guiding patientsto get out from their bed until they can ambulation. Aim of research is known comparison ofadministration health education of early mobilitation to the patient with post operation of SCwith long day care in the hospital of Bengkulu City. Kind of research is Quasi Experiment fordetermine whether ther is a causal effect between indedendent variable and dependent variablewith compare one or more experiment groups fed with the comparison groups. Sample takenConsecutive Sampling. Population is mother of labor in intervention groups as much as 21respondents and 21 respondent for control groups. Bivariate analysis of median long day careto the mother group that administration health education of early mobilitation to the motherpost operation section caesaria as much as 3.00 with minimum value of long day care was 2and maximum value was 6.00 and average and standard deviation was 0,20. Result of MannWhitney Statistic Test showed that p=0,00 value means there was significant correlationadministration education of mobilitation to the long day care to the mother with post operationof section caesaria. Result of Multivariate Analysis together between health education ofearly mobilitation and age with long day care, it showed that p=0,00 value means there wassignificant correlation between health education of early mobilitation and age with long daycare. By controlling variable of age could prediction long day care as much as 51%.Health education of early mobilitation to the intervention groups showed that average of longday care faster than control groups. There was significant correlation between healtheducation of early mobilitation to the long day care for patient post operation section caesaria.
Efeitos do treinamento intervalado de alta intensidade na aptidão física relacionada à saúde em crianças e adolescentes: uma revisão sistemática
Authors: Souza Rafael Luiz Mesquita , Aidar Felipe José , Schutz Sí­lvia , Santos Jymmys Lopes dos , Soares Nara Michelle Moura , De Araújo Silvan Silva , Marçal Anderson Carlos
Published: January 2021

Introdução: O treinamento intervalado de alta intensidade (HIIT) é capaz de promover melhora da saúde e condicionamento físico e contribuir para o aumento da capacidade cardiorrespiratória (VO2máx), da resistência muscular localizada e melhora da composição corporal. No entanto, seus efeitos sobre a aptidão física relacionada a saúde de crianças e adolescentes ainda não são bem esclarecidos. Objetivo: O objetivo do estudo foi analisar a eficácia do HIIT na aptidão física relacionada a saúde de crianças e adolescentes. Métodos: O presente estudo analisou artigos das bases de dados (SportDiscus, Web of Science, Medline via PubMed, Scopus, Scielo e Bireme). Foi aplicada a estratégia PICO para selecionar os artigos e o CONSORT para avaliar a qualidade dos ensaios clínicos randomizados. Foram encontrados 511 artigos. Desse total, 101 artigos foram elegíveis para a análise do resumo. Resultados: Ao final do processo de seleção resultaram em 10 artigos que compuseram os critérios de inclusão. Os resultados sugerem que entre as variáveis analisadas pelos artigos referentes a aptidão física relacionada a saúde, o HIIT demonstrou eficácia na VO2máx, índice de massa corporal e percentual de gordura nessa população. Conclusão: Contudo, não foi possível afirmar que o HITT promoveu ajustes na flexibilidade, na força e na resistência muscular localizada, sendo necessário maiores estudos para avaliar seus efeitos sobre a aptidão física relacionada a saúde
Alanine Aminotransferase is a Predictor of NAFLD Activity Score for Diagnosing Non-alcoholic Steatoehpatitis
Authors: Das Dulal Chandra , Alam Sheikh Mohammad Noor E , Das Ripon , Mohsena Masuda , Mahtab Mamun Al
Published: January 2021

Nonalcoholic fatty liver disease (NAFLD) is a metabolic disorder characterized by excessive triglyceride- accumulation in hepatocytes. NAFLD has a multifactorial etiology and a combination of environmental, genetic and metabolic factors play a role in the development of advanced disease. NAFLD consists of a wide spectrum of conditions, ranging from simple steatosis to nonalcoholic steatohepatitis (NASH) which can progress to cirrhosis and hepatocellular carcinoma (HCC). Despite the high prevalence and severity of hepatic illness, NAFLD remains under diagnosed, because of few symptoms, lack of accurate laboratory markers. The accurate diagnosis of NASH remains dependent on specific histological parameters in liver biopsy. Although liver biopsy remains the ‘gold standard’, there are practical limitations, including costs and risks. There is an increasing requirement for simple, less invasive, highly accurate and affordable screening tools. Alanine aminotransferase (ALT) has been proposed as a noninvasive and available marker for assessment of NASH. A hospital based observational study was carried out for a period of two years in the Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Data were analyzed by SPSS version 16. Statistical inference were done by estimating distribution, Chi-square test and student’s t-test respectively. Fifty (50) patients were analysed.Twenty five were NASH and twenty five were simple steatosis. ALT in NASH group  were 97.0±51.5IU/L and insimple steatosis group were 55.5±28.6 IU/L. In NASH group 64%  of raised ALT had NASH . In Non-NASH group 16% of raised ALT had no NASH.There was significant difference in the NAFLD activity score for diagnosing NASH between elevated and normal ALT( P  value 0.001).

Bangladesh Med J. 2019 May; 48 (2): 1-6
Tuberous Sclerosis Complex Associated Lymphangioleiomyomatosis Presenting with Spontaneous Pneumothorax and Renal Angiomyolipomas
Authors: Rahman Mohammed Mirazur , Sarkar Shish Mohammad , Musa Manzurul Ibrahim , Habib Farjana Binte , Hasan Md Nazmul , Hossain AKM Mosharraf
Published: January 2021

Tuberous sclerosis complex (TSC) is a rare autosomal dominant disorder manifested by involvement of multisystem including skin, central nervous system, heart, kidneys and eyes. Lymphangioleiomyomatosis (LAM) is also a multisystem disorder that primarily affects the lungs. We report a case of tuberous sclerosis complex associated lymphangio-leiomyomatosis (TSC-LAM) in a 26-year-old female patient who was presented with spontaneous pneumothorax and renal angiomyolipomas. In clinical examination; We found multiple angiofibromas over her face, shagreen patches over upper and lower back and ungual fibromas in both fingers and toes. HRCT of chest revealed right sided pneumothorax with multiple thin walled cysts in both lungs. Ultrasonogram (USG) and Computer Tomography (CT) scan of abdomen revealed bilateral angiomyolipomas. We managed her pneumothorax with intercostal chest tube drainage and oxygen inhalation.

Bangladesh Med J. 2019 May; 48 (2): 51-54
Management of Flood Disaster in Resource Poor Country: Bangladesh Perspective
Authors: Asaduzzaman M
Published: January 2021

Abstract not available

Journal of Science Foundation 2019;17(2):40-41
Age, Gender and Common Site of Haematoma Formation among Acute Subdural Hematoma Patients: Experience of 48 Cases in Bangladesh
Authors: Uddin Kalim , Salam Md Abdus , Haque Ashraful , Khan Amir Md , Rahman Md Mahfuzur , Hussain Ahmed Riyad , Islam Rafiqul
Published: January 2021

Background: Acute subdural hematoma can occurs in different age group of patients in both male and female.

Objective: The purpose of the present study was to observe the age and gender distribution among acute subdural hematoma patients.

Methodology: This cross-sectional study was carried out in the Neurosurgery Department of Dhaka Medical College Hospital, Dhaka, Bangladesh from January 2011 to August 2012 for a period of one year and eight months. Patients with acute subdural hematoma who fulfil the inclusion criteria for surgery and got admitted were selected as study population. Acute Subdural hematoma patient of any age, both sex with GCS 5 to 13, thickness of hematoma more than l0 mm, midline shift more than 5 mm, pupil reacting to light and patient presented within 72 hours of injury were included for this study. At admission, a detailed history of the illness was taken from the patient or attendant, thorough general and neurological examinations were carried out and were recorded.

Result: A total number of 48 patients were recruited for this current study. The mean age of the patients was 32.39±11.63 years and their age ranged from 10 to 56 years. The male and female ratio was 5:1. Out of 48 patients 17(31.25%) cases were fronto-temporal. Temporo-parietal were 16(33.3%) patients. Fronto-temporo-parietal were 7(14.5%) cases. Parietal were 5(10.41%) cases. Frontal were 3 (6.25%) case.

Conclusion: In conclusion majority of the patients are male young adults presented with fronto-temporal and temporo-parietal region of shull.

Journal of Science Foundation 2019;17(2):54-57
Autonomic and Motor Involvement among the Patients Presented with Prolapse Lumbar Intervertebral Disc
Authors: Ali Md Rustom , Chowdhury Ayesha Afroz , Ahmed Md. Farhad , Khalil Md Ibrahim
Published: January 2021

Background: Involvement of autonomic and motor nervous system are very crucial for the patients suffering from prolapse lumbar intervertebral disc.

Objective: The purpose of the present study was to see the involvement of autonomic and motor nervous system of the patients suffering from prolapse lumbar intervertebral disc.

Methodology: This cross-sectional study was carried out in the department of Neurosurgery at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from March 2006 to October 2007 for a period of one and half year. Prolapse lumbar intervertebral disc (PLID) patients who were admitted in the Department Neurosurgery at BSMMU, Dhaka, Bangladesh after clinical and radiological evaluation were selected as study population. The involvement of autonomic and motor nervous system were examined among the patients suffering from prolapse lumbar intervertebral disc.

Result: A total of 59 hospital-admitted cases of PLID were included in the study. The mean age of the patients was 40.8±11.9 years and the lowest and highest ages were 21 and 65 years respectively. Majority of the patients had intact bladder function which was 57(94.9%) cases and the remaining 2(3.4%) cases had incontinence of urine. More than half (54.2%) of the subjects exhibited weak extensor hallucis longus test, while 30.5% had weak flexor digitalis longus test.

Conclusion: In conclusion motor dysfunction is very high, but low rate of autonomic abnormalities are found among the patients suffering from prolapse lumbar intervertebral disc.

Journal of Science Foundation, January 2020;18(1):3-6
Smart Interrogation System by Detection of Visual Focus of Attention
Authors: Debnath P. P. , Rashed M. G. , Das D. , Basar M. R.
Published: January 2021

The paper presents an approach to detect and control the focus of attention of the suspect using his/her eye gaze and head movement direction to build up an automatic interrogation system- specially to detect lies. To this point, we classified interrogation conversation into different criteria and identified the fatal ones. At first, we conducted psychological experiments on the sampled population to detect the different parameters connected with various symptoms when the suspect tells lies and build our knowledgebase with the results. This knowledgebase helps the system to make strategic decisions and to optimize accuracy. A monitoring camera captures continuous interrogation and feeds the frames to our proposed system. 3D head tracker is used to track the head from image and Active Shape Model (ASM) is utilized to localize face points. Vector Field of Image Gradient (VFIG) is calculated to track the eyeball and its rotation within the eye area. Random eye and head movement, change of eyebrow at the critical level of questionnaire provide us the possibility of detecting lies. Finally, experiments are conducted in a controlled environment to validate our psychological findings.
Verbesina encelioides: A Fast Spreading Weed in Semi-arid Regions of North-Western India. Is Climate Change Responsible?
Authors: Mehal K. K.
Published: January 2021

Alterations in rainfall pattern and rise in temperature along with various anthropogenic disturbances are contributing greatly to biological invasion. In response to ongoing climate change, the sub-tropical and semi-arid regions are shifting towards dry deserts and arid regions, which create a propitious chance for the establishment of highly efficient and opportunistic invasive plant species at the cost of native vegetation. Verbesina encelioides is one of such exploitative plants spreading fast in many semi-arid as well as arid regions of the world. Although the presence of V. encelioides dates back to 1960s, but its emergence as a dominant invasive weed of dry areas is recent in India. The present study focused on the rapid spread of V. encelioides in the north-western states of India owing to its ecological traits as well as changing climate patterns of the country.
Diagnóstico de Manguezais Periurbanos após 20 anos de impactos antrópicos
Authors: Blotta Katia Domingues , Guimarães Luciana Lopes , Braz Eliane Marta Quinoñes , Magenta Mara Angelina Galvão , Ribeiro Renan Braga , Giordano Fábio
Published: January 2021

O crescimento das zonas urbanas ao longo das últimas décadas vem interferindo na dinâmica dos manguezais, prejudicando a prestação de serviços ecossistêmicos. O objetivo do presente estudo foi verificar o perfil da distribuição das espécies vegetais, alterações na estrutura do solo e nos parâmetros que atestam a qualidade da água em manguezais periurbanos às margens do Rio Itanhaém, no município de Itanhaém (São Paulo, Brasil). Os resultados obtidos neste estudo, realizado entre os anos de 2017 e 2019, foram confrontados com estudos conduzidos entre os anos de 1996 e 1998, refletindo numa comparação de quase duas décadas de incremento na urbanização, em face do aumento populacional de 31% entre 1997 e 2017. As análises sugeriram alteração da composição de espécies vegetais das parcelas estudadas, especialmente naquelas mais próximas ao Rio Itanhaém. Os resultados das análises de sedimento demonstraram incremento de matéria orgânica no solo das estações de coleta e as análises da qualidade das águas nos diferentes pontos de coleta mostraram resultados em desacordo com os parâmetros estabelecidos pelas Resoluções CONAMA 357/05 e 274/00. A partir dos resultados obtidos, foi possível verificar que a velocidade com que vem se processando a expansão e especulação urbana nas cidades litorâneas, tem levado a uma degradação do ecossistema manguezal e entende-se que seja da maior importância haver o monitoramento da vegetação litorânea.
Utilização de óleo de moringa na cicatrização de feridas cutâneas em ratos
Authors: Luciano Leonardo Luca , Soares Evelise Aline , Garcia José Antonio Dias , Pereira Andréa Aparecida , Miranda Adélia Pereira , Silva Délcio Bueno da , Fernandes Aline , Silva Thiago Donizeth da , Lima Samuel José Fernandes de , Garcia  Erika Kristina Incerpi , Lima Ciderleia Castro de
Published: January 2021

Introdução: A moringa é uma planta tropical pertencente à família Moringaceae e apresenta propriedades cicatrizantes pouco conhecidas. Objetivo: avaliar o efeito do óleo de moringa (Moringa oleífera L.) na cicatrização cutânea em ratos (Rattus novergicus). Metodologia: Foram utilizados 45 ratos (Rattus norvegicus), wistar, com três meses de idade, divididos em três tratamentos: GCN (grupo controle negativo): aplicação de creme não iônico; GOM (grupo óleo de moringa): adição de 10% do óleo de moringa ao creme não iônico; GCP (grupo controle positivo): aplicação de creme à base de sulfadiazina de prata a 1%. Os ratos sofreram uma incisão de 1,0 cm circular na região dorso-cervical e as feridas foram tratadas com os cremes. Resultados: Foi observada a evolução do processo cicatricial e medido o diâmetro das feridas. No 3º, 7º e 14º dia do experimento, foram sacrificados cinco animais de cada grupo para a realização da contagem de macrófagos, neovasos e fibroblasto. A contagem de macrófagos mostrou aumento (p<0,05) após sete dias de aplicação dos cremes em todos os tratamentos. Os neovasos e fibroblastos não aumentaram (p>0,05) após sete dias de aplicação dos cremes nos tratamentos GCN e GCP em relação a três dias após início das aplicações, observando-se aumento (p<0,05) somente no tratamento GOM. Conclusão: As evidências obtidas mostraram que a aplicação tópica de creme acrescido com 10% de óleo de moringa em pele lesada influenciou em eventos celulares, otimizando a reparação tecidual e atenuando o processo inflamatório.
Florística e germinação ex situ do banco de sementes do solo em diferentes níveis de luminosidade
Authors: Cordeiro Iracema Maria , Lameira Osmar Alves , Neves Raphael Prado , Schwartz Gustavo
Published: January 2021

Bancos de sementes do solo trazem informações sobre a flora atual e permitem cenários futuros sobre as comunidades vegetais. O objetivo deste trabalho foi determinar o percentual de germinação ex situ de um banco de sementes em diferentes níveis de luminosidade. A amostragem ocorreu em floresta primária explorada sob pousio no município de Moju, estado do Pará, Brasil. Foram coletadas 10 amostras compostas por quatro amostras simples em 10 parcelas da camada superficial do solo (5 cm). As amostras foram mantidas em casa de vegetação e distribuídas aleatoriamente em bandejas de isopor sob três condições de luminosidade: Sombra (casa de vegetação + 70% de sombrite); Sombra Média (casa de vegetação + 30% de sobrite) e Pleno Sol, com cinco repetições cada. Após 120 dias, o banco de sementes apresentou 414 plântulas de 61 espécies, 48 gêneros e 34 famílias. Deste total, 27,78% dos indivíduos germinaram nos três ambientes analisados. O ambiente com maior germinação de indivíduos foi Sombra Média (F = 140,25; p = 0,0001; CV = 3,60%), o qual também incluiu 48,15% das espécies germinadas. O banco de sementes apresentou alta diversidade florística com predominância de espécies arbóreas, pioneiras e zoocóricas. Desta forma, condições ambientais determinam a germinação do banco de sementes, com destaque ao ambiente Sombra Média e às famílias Fabaceae, Rubiaceae e Urticaceae.
Influencia de la solidez y el número de álabes en una turbina de eje vertical tipo H-darrieus
Authors: Tobon-Tobon Nelson , Henao-González Kevin Alexander , Burbano-Hernandez Andrés Felipe , Sierra-Del Rio Jorge , Hincapié Zuluaga Diego Andrés
Published: January 2021

El siguiente estudio propone el análisis de una turbina hidrocinética de eje vertical tipo H-Darrieus que puede ser implementada en las regiones no interconectas al sistema eléctrico colombiano en especial las zonas costeras. El objetivo del estudio es analizar el número de álabes en la eficiencia de la turbina hidrocinética, para esto se proponen 27 tipos de rotores, en los cuales, se varia el número de álabes desde 2 hasta 10 para 3 valores de solidez diferentes. Concluyendo que a partir de 3 álabes se reducen los torques negativos producidos, incrementando la capacidad de autoarranque, sin embargo, cuando el número de álabes aumenta el torque total generado por la turbina disminuye lo que conlleva a una disminución en la eficiencia.
A complete classification of de mersenne´s primes and its iomplications for computing
Authors: Acevedo-Agudelo Yeisson Alexis
Published: January 2021

A study of Mersenne’s primes is carried out using the multiplicative group modulo 360 and a complete classification is obtained by its residual classes. This allows the search for Mersenne’s primes to be classified into four subgroups mutually exclusive (disjoint) and contributes to the ordered selection of exponents to be computationally tested. According to this idea, Mersenne’s trapeze is presented with the purpose of giving a geometric representation for this classification. Finally, from one of the theorems presented and proven for primes in modulo 360, a conjecture is established that could be solved by computing.
Análisis de un controlador adaptable con observador de estado por modos deslizantes para un modelo de tratamiento de diabetes tipo 1
Authors: Núñez-López Juan David , Villa-Tamayo María F. , Arango-Restrepo Juan Pablo , Botero-Castro Héctor A.
Published: January 2021

El desarrollo del Páncreas Artificial, el cual consiste en la implementación de una bomba de infusión continua de insulina y de sensores para el monitoreo de glucosa en la sangre, es una prioridad para el tratamiento de personas con diabetes tipo 1. Para lograr la automatización completa de este proceso se han propuesto varias estrategias de control con el objetivo de mantener los niveles de glucosa en la sangre en el rango de normoglucemia. Entre las estrategias desarrolladas se destacan las basadas en control adaptable, para contrarrestar el efecto de las variaciones fisiológicas inherentes al paciente. Sin embargo, estas estrategias requieren la medición completa del estado, lo cual no es una tarea fácil debido al costo de los sensores y a la dificultad inherente en la medición directa de variables fisiológicas. Por lo tanto, en este trabajo se usa una estrategia de control adaptable con estabilidad garantizada para un modelo de control de insulina y se diseña un observador de estado no lineal por modos deslizantes, con el fin de estimar las variables de estado que requiere el controlador. Con el sistema completo control-observador se logran resultados satisfactorios al compensar la ingesta de alimentos y los errores entre los parámetros del modelo y del sujeto.
Mantenimiento y reparación de vías usando un sistema robótico en la nube
Authors: Torres Ingrid Durley , Madrigal Mejia Andrés Felipe , Torres Sebastián , Guzmán-Luna Jaime Alberto
Published: January 2021

La revolución del internet de las cosas - IoT, genera nuevos retos para el campo de la robótica; Para la construcción de las aplicaciones y comunicación de los sistemas robóticos, con la nube, fueron creados protocolos y conceptos, que facilitan y estandarizan la interconexión, algunos de estos conceptos son: servicios web, programación XML, sistema WS-BPEL, Arquitectura Orientada Servicio, Big data y computación en la nube. Este artículo, muestra una aplicación específica de la integración del concepto de IoT con la robótica, representado por un sistema de reparación y mantenimiento de vías autónomo, con un sistema robótico en la nube, el cual utiliza servicios web y protocolos de comunicación como XML y BPEL para la interconexión entre la información necesaria para la reparación y mantenimiento de las vías, usados en la toma de decisiones y tareas asignadas entre los robots. De esta manera, se demuestra, cómo es posible articular todos los conceptos, para lograr soluciones en un escenario real de reparación de vías.
Identificación de microorganismos biorremediadores de suelos agrícolas del norte de Antioquia para degradación del clorpirifos
Authors: Hernandez-Angel Marta Lucia , Lopez Ena Patricia , Jaramillo Granda María Camila , Posada Usuga Anlly Paola
Published: January 2021

En los últimos años se ha encontrado cantidad de agroquímicos acumulados en suelos agrícolas que los vuelven infértiles, disminuye la calidad de los productos alimenticios, contaminan el suelo y aguas subterráneas. Un agroquímico utilizado de manera indiscriminada es el clorpirifos, principal producto de hidrólisis el 3,5,6-tricloro-2-piridinol. En este proyecto se unen dos estrategias de biorremediación para mitigar la problemática de los agroquímicos, se realiza análisis sobre capacidades de degradación de microorganismos del suelo contaminado, identificación para potenciar la facultad de estos, determinación de concentraciones viables para realizar biodegradación en los suelos agrícolas y disminuir la tasa de contaminación en el ecosistema y los niveles de intoxicación al ser humano. El objetivo de esta investigación es analizar y evidenciar la biodegradación del pesticida clorpirifos a diferentes concentraciones de microorganismos y solución de nutrientes, con el propósito de nivelar la sobrecarga de agroquímicos y evitar una mayor contaminación en el suelo, cultivos y aguas subterráneas.
Extraction and Characterization of Polyhydroxybutyrate (PHB) From Bacillus flexus MHO57386.1 Isolated From Marine Sponge Oceanopia arenosa (Rao, 1941)
Authors: D Aryaraj , V S Pramitha
Published: January 2021

Polyhydroxybutyrate (PHB) is the most widely studied biodegradable plastic that does not release any toxins or residues in the environment like petroleum based plastics. This work has been undertaken to screen PHB accumulating microorganisms from marine sponges and a total of sixteen isolates were collected and purified. Screening of isolated strains was done by Nile blue staining and observed under Leica LSCM to confirm the production of PHB. Yellow pigmented AB8a isolate from Oceanopia arenosa scored positive for PHB accumulation and subjected to morphological, biochemical and phylogenetic characterization. The biopolymer was extracted by dispersion of sodium hypochlorite and chloroform solution and characterized by FT-IR and 1H NMR for the confirmation as PHB. The highest PHB production (70.25%/100 ml) was achieved at pH 7.0 by applying dextrose as medium at incubation temperature 30°C and 150 rpm agitation speed. The FTIR spectrum of the PHB sample showed major peaks at 3457, 1692, 1550, 1454, 1420, 1190 and 1050 cm-1, whereas the remaining peaks are closely laid between 3450 cm-1 and 600 cm-1. 1H NMR spectrum of PHA isolated from dextrose media indicated characteristic signals of PHB. The spectrum also revealed the presence of three groups of signals characteristic of PHB by the doublet at 1.3 ppm attributed to the methyl group coupled to one proton; and the spectrum of the quadruplet at 2.57 ppm, the methylene group adjacent to an asymmetric carbon atom bearing a single proton and the multiplet at 5.28 ppm indicated signals of PHB. The PHB accumulated bacterium identified as Bacillus flexus strain based on characterization studies and 16S rRNA sequence analysis and confirmed the presence of intracellular accumulated polymer substantiated as PHB.
The Socialist Calculation Debate and the Commons
Authors: Schröter Jens
Published: January 2021

The paper discusses the relation between "The Socialist Calculation Debate" and the "Commons"
Analisis Faktor-Faktor Yang Mempengaruhi Pola Permukiman Sebagian Wilayah Kecamatan Kambu Kota Kendari
Authors: Mucolifah Maryatun , Ido Irfan , Harimudin Jamal
Published: January 2021

Jumlah penduduk Indonesia dari tahun ke tahun selalu bertambah. Kondisi ini akan membawa konsekuensi semakin bertambahnya kebutuhan ruang hidup yang berupa lahan permukiman. Penelitian ini bertujuan untuk: (1) mengetahui dan memahami pola permukiman penduduk sebagian wilayah  Kecamatan Kambu Kota Kendari, dan (2) mengetahui faktor-faktor yang mempengaruhi pola permukiman penduduk sebagian wilayah  Kecamatan Kambu Kota Kendari. Metode analisis yang digunakan pada penelitian ini adalah: (1) Nearest Neighbour Analysis dan (2) analisis scoring/pembobotan. Hasil Penelitian ini menunjukan bahwa: (1) sebagian wilayah Kecamatan Kambu terdapat empat kelurahan, yaitu Kelurahan Kambu, memiliki pola mengelompok dan acak di beberapa RT, Kelurahan Lalolara, Padaleu, dan Mokoau memiliki pola mengelompok. Dan memiliki tiga kelas permukiman, yaitu kelas permukiman teratur, semi teratur, dan tidak teratur dari beberapa RT/RW nya; (2) faktor-faktor yang  berpengaruh pada pola permukiman, yaitu faktor aksessibilitas, pendapatan atau ekonomi, aspek sosial, dan aspek budaya. Kata kunci:   Permukiman, Pola Permukiman, Faktor-Faktor Pola Permukiman, Nearest    Neighbour Analysi
Penicillin Allergy De-labeling Results in Significant Changes in Outpatient Antibiotic Prescribing Patterns
Authors: Hills Thomas , Arroll Nicola , Duffy Eamon , Capstick Janice , Jordan Anthony , Fitzharris Penny
Published: January 2021

Unverified penicillin allergies are common but most patients with a penicillin allergy label can safely use penicillin antibiotics. Penicillin allergy labels are associated with poor clinical outcomes and overuse of second-line antibiotics. There is increasing focus on penicillin allergy “de-labeling” as a tool to improve antibiotic prescribing and antimicrobial stewardship. The effect of outpatient penicillin allergy de-labeling on long-term antibiotic use is uncertain. We performed a retrospective pre- and post- study of antibiotic dispensing patterns, from an electronic dispensing data repository, in patients undergoing penicillin allergy assessment at Auckland City Hospital, New Zealand. Over a mean follow-up of 4.55 years, 215/304 (70.7%) of de-labeled patients were dispensed a penicillin antibiotic. Rates of penicillin antibiotic dispensing were 0.24 (0.18–0.30) penicillin courses per year before de-labeling and 0.80 (0.67–0.93) following de-labeling with a reduction in total antibiotic use from 2.30 (2.06–2.54) to 1.79 (1.59–1.99) antibiotic courses per year. In de-labeled patients, the proportion of antibiotic courses that were penicillin antibiotics increased from 12.81 to 39.62%. Rates of macrolide, cephalosporin, trimethoprim/co-trimoxazole, fluoroquinolone, “other” non-penicillin antibiotic use, and broad-spectrum antibiotic use were all lower following de-labeling. Further, antibiotic costs were lower following de-labeling. In this study, penicillin allergy de-labeling was associated with significant changes in antibiotic dispensing patterns.