bluuebunny/crossref_metadata_2025 huggingface dataset:
Managing Intracranial Hemorrhage in Patients with a Durable Continuous Flow Left Ventricular Assist Device
Authors: Jack Godly , Barker Phil , Searcy Ryan , Katz Jason N.
Published: October 2019

Background

While intracranial hemorrhage (ICH) is a known complication of left ventricular assist device (LVAD) support, and is associated with high morbidity and mortality, optimal care pathways have neither been elucidated nor reported. We describe management of LVAD patients following ICH, with a focus on anticoagulation, operative interventions, care team designation, complications, and outcomes.

Methods

We retrospectively reviewed all durable continuous-flow LVAD implantations at our academic medical center from January 2007 to July 2018. Patients who experienced ICH after LVAD were identified. We defined baseline and ICH characteristics, medical and surgical interventions, care teams, and outcomes including death, device thrombosis, ischemic stroke, and hemorrhage expansion.

Results

A total of 321 patients underwent LVAD implantation during the study period, and 27 (8%) developed ICH (17 intraparenchymal, 7 subdural, 2 subarachnoid, 1 intraventricular) while on support. Twenty-five were anticoagulated at onset of bleed. Of those, 13 were managed with immediate cessation of anticoagulation and administration of reversal products (Group A). Group A had a median of 6 days off anticoagulation and 60 days of follow up with 1 patient (8%) developing device thrombosis at day 8, 1 (8%) developing subsequent ischemic stroke at day 14, and 4 (31%) with ICH expansion. Seven patients had anticoagulation stopped at onset of bleed without administration of reversal products (Group B). With a median of 2 days off anticoagulation and 2 days of follow up, no patients in Group B developed ischemic stroke or device thrombosis while 1 (14%) had ICH expansion. Five patients had anticoagulation continued at onset of bleed (Group C) with a median follow up of 330 days. One (20%) developed device thrombosis at day 5 while 2 (40%) developed ICH expansion. Four patients with subdural hemorrhage underwent Burr hole drainage with all 4 surviving to discharge. Two patients with intraparenchymal hemorrhage underwent open craniotomy with neither surviving to discharge. An interdisciplinary discussion occurred in all cases. Following ICH, only one-third of patients in the study survived to 6 months.

Conclusion

LVAD patients who experience an ICH have variable outcomes. Their care is multidisciplinary and can involve operative intervention. The discontinuation and reversal of anticoagulation is generally well-tolerated, with a low risk for early device thrombosis. Like for many hemorrhagic complications of LVADs, ICH often persists or worsens. Additional investigation is needed to elucidate the most optimal management strategies.
Implantation of Left Ventricular Assist Device in the setting of heavily calcified left ventricular apex using an apex preserving technique
Authors: A Salas de Armas Ismael , Akay Mehmet , Patel Jayeshkumar A , Patel Chandni J , Patel Manish K , Akkanti Bindu , Kar Biswajit , Gregoric Igor
Published: October 2019

A heavily calcified ventricular apex represents a challenging, rare and unique situation in LVAD implantation. A 44-year-old male was admitted with myocardial infarction. Left heart catheterization was complicated by episodes of ventricular fibrillation. After an acute stabilization with veno-arterial extracorporeal membrane oxygenation (VA-ECMO), an LVAD implantation was approved. Pre-operative work-up had shown a heavily calcified ventricular apex and an intraventricular thrombus, which was confirmed intraoperatively. To retain a viable ventricular geometry, the decision was made to preserve the calcified apex rather than to excise the entire calcified left ventricular aneurysm. Sutures for the inlet cannula were placed around the calcific apex (Apex Preserving) away from the core site, parachuting the inflow sewing ring into an intramyocardial position (Telescope) and assuring hemostasis by placing a felt strip on the epicardial tissue in a purse string fashion (Cerclage). The HeartMate II LVAD inflow cannula was secured into the sawing ring, and the rest of the procedure was conducted in the standardized fashion. The patient was discharged into a rehabilitation center eight weeks after LVAD implantation. Thus, if the calcific area is maintained by coring just the inflow site, the spherical shape of the ventricle is maintained to all for better positioning of the inlet cannula. The second suture line enhances hemostasis around the inflow insertion site and stays away from the calcium, which sits in a deeper layer. This procedure, the apex preserving cerclage technique (APCT), does not increase surgical time and reinforces the tissue around the inlet site.
Successful Extracorporeal Membrane Oxygenation in the Management of Acute Respiratory Distress Syndrome and Cardiopulmonary Collapse Secondary to Amniotic Fluid Embolism
Authors: Roy Sumon , Biniwale Nishit , Pendela Venkata , Oates Patricia , Wojciechowski Katrina , Feitell Scott
Published: October 2019

Amniotic fluid embolism (AFE) is one of the most devastating complications of pregnancy that typically manifests as acute cardiopulmonary collapse during delivery or in the postpartum period. The potential role of extracorporeal membrane oxygenation (ECMO) as a management technique in severe cases of AFE remains largely unknown. In this report, we present the first case, to our knowledge, of successful implementation of ECMO as a life-saving measure in a case of hemorrhagic shock due to postpartum bleeding complicated by severe AFE leading to acute respiratory distress syndrome (ARDS) ultimately requiring tracheostomy. Hemodynamic decompensation is often rapid but transient in cases of severe AFE, and we recommend early consideration of ECMO implementation given its vital utility in these critical moments.
𝜔+-Type Index of GL+(2)-Paths
Authors: Liu Sai , Wang Wei
Published: October 2019

In this paper, we establish an

ω
+

{\omega^{+}}

-type index theory for paths in the general linear group

GL
+

⁢

(
2
)

{\mathrm{GL}^{+}(2)}

. This is done by the complete homotopy classification for such paths. We also compare this index theory with the ω index theory for paths in the symplectic group

Sp
⁢

(
2
)

{\mathrm{Sp}(2)}

and obtain a generalization of Bott formula for iterated paths in

GL
+

⁢

(
2
)

{\mathrm{GL}^{+}(2)}

. As applications, the minimal periodic solution problem and the linear stability of general differential systems are studied.
Tau Misfolding Efficiently Propagates between Individual Intact Hippocampal Neurons
Authors: Hallinan Grace I. , Vargas-Caballero Mariana , West Jonathan , Deinhardt Katrin
Published: October 2019

Neurofibrillary tangles, formed of misfolded, hyperphosphorylated tau protein, are a pathological hallmark of several neurodegenerations, including Alzheimer's disease. Tau pathology spreads between neurons and propagates misfolding in a prion-like manner throughout connected neuronal circuits. Tauopathy is accompanied by significant neuronal death, but the relationships between initial tau misfolding, propagation across connected neurons and cytotoxicity remain unclear. In particular the immediate functional consequence of tau misfolding for the individual neuron is not well understood. Here, using microfluidic devices to recreate discretely organized neuronal connections, we show that the spread and propagation of misfolded tau between individual murine neurons is rapid and efficient; it occurs within days. The neurons containing and propagating tau pathology display selective axonal transport deficits but remain viable and electrically competent. Therefore, we demonstrate that seed-competent misfolded tau species do not acutely cause cell death, but instead initiate discrete cellular dysfunctions.

SIGNIFICANCE STATEMENTPublic awareness of progressive neurodegenerations such as dementias associated with aging or repetitive head trauma is rising. Protein misfolding underlies many neurodegenerative diseases including tauopathies, where the misfolded tau protein propagates pathology through connected brain circuits in a prion-like manner. Clinically, these diseases progress over the course of years. Here we show that the underlying protein misfolding propagates rapidly between individual neurons. Presence of misfolded tau is not directly cytotoxic to the neuron; the cells remain viable with limited deficits. This suggests that neurons with tau pathology could be rescued with a therapeutic disease modifier and highlights an under-appreciated time window for such therapeutic intervention.
Exploring Mechanisms of Narrative Persuasion in a News Context: The Role of Narrative Structure, Perceived Similarity, Stigma, and Affect in Changing Attitudes
Authors: Tamul Daniel J. , Hotter Jessica C.
Published: October 2019

Two exploratory studies demonstrate, for the first time, that narrative persuasion can diminish the stigma attached to social groups featured in journalistic narratives. Study 1 shows narrative format improves stigma toward Syrian refugees indirectly through narrative engagement, perceived similarity, and meaningful affect. Decreases in stigma also improved attitudes toward refugees. Study 2 replicates these findings against a separate participant pool, an additional story topic, and compares changes in engagement, stigma, and attitude to a non-narrative fact sheet and a control condition. A preregistered third study seeks to validate the finding that narratives can elicit destigmatization and disentangle the roles of story exemplars from story structure.
The Analysis of Learning Model in Office Administration Training at Semarang Job Training Development Center
Authors: Mujiati Mujiati , Raharjo Tri Joko , Rifai RC Achmad
Published: October 2019

One reason for the high level of secondary and vocational school participation in quality that does not meet the competency standards required by the labor market. The need for new breakthroughs in order to improve the quality of human resources as an effort to prepare students in the world of work. The purpose of this research is to describe and analyze: (1) The learning model that is implemented in the office administration training that refers to the principle of adult training, (2) the readiness of the participants after completing the training. This research uses qualitative approach method. The subject is the section of training, training instructors, FMD team and trainees. Engineering data collection done by observation, interviews, and documentation. Data analysis techniques include the collection of data, data presentation, data reduction and withdrawal of the conclusion. An examination of the validity of the data using triangulation of sources and method. The research results showed that: (1) the model of learning which is implemented in office administration training refers to information processing model, personal model and behavior modification model. Implementation of the three models includes: learning syntax, social systems, reaction principles, support systems, instructional impacts and impact accompaniment. In the implementation of learning model in office administration, the training is based on adult learning principle, (2) participants' readiness is nurtured through job training activities that include 14 competency units, softskills activities, and character building.
Should we genotype the sperm of fathers from patients with ‘de novo’ mutations?
Authors: Pasmant Eric , Pacot Laurence
Published: October 2019

In this issue of the European Journal of Endocrinology, Lin et al. report a de novo heterozygous nonsense variant in the PHEX gene in an X-linked hypophosphatemic rickets patient. The authors described a germline mosaicism in the sperm of the unaffected father of the proband, providing the opportunity to discuss the concept of isolated germline mosaicism. In addition to the genetic information passed on from generation to generation, each of us is born with a small number of novel genetic changes -de novo mutations- that occurred either prezygotically or postzygotically. When de novo mutational events occur prezygotically, mutation may pre-exist in a parent who is mosaic but the mutation might be inherited in the zygote and potentially in all cells of the developing offspring resulting in a de novo disease phenotype. Only somatic cells (mainly from blood and skin) are routinely used in genetic analyses, and a hint about possible germline mosaicism can be obtained only if somatic mosaicism is detected, or if more affected siblings are born with an identical de novo variant. There is now a wide range of disorders for which the occurrence of parental germline mosaicism has been reported. Interestingly, Lin et al. analyzed eight different tissues of the proband’s father (including sperm), which allowed a conclusive assessment of his mosaicism extension. This study suggests that sperm analysis could more often be performed in our routine genetic screening for germline mosaicism in fathers of patients with apparently de novo mutations.
The Expression of Social and Emotional Competencies of Leadership in Lithuanian Organizations: The Gender Approach
Authors: Šilingienė Violeta , Stukaitė Dalia
Published: October 2019

The phenomenon of gender leadership is a controversial object in contemporary leadership studies. These days, the possibilities of traditional leadership have been limited by the ongoing dynamic, global changes, which have influenced the emergence of female leadership as an independent phenomenon and its separation from the male leadership. Presently, possibilities exist to form new insights about gender leadership. Scholars have begun an intense scientific discussion on the advantages and disadvantages of male and female leadership. The goal of this paper is to disclose the social and emotional leadership competencies of different gender employees. The employed research methods are as follows: an analysis and synthesis of scientific literature with the aim of revealing the peculiarities of gender leadership and defining leadership as a set of social and emotional competencies; quantitative research conducted using a questionnaire-based survey with the aim of empirically determining the manifestation of social and emotional leadership competencies in terms of gender leadership. The theoretical analysis allows us to identify the fundamental trends of gender leadership research. The empirical basis of this article comprises the results of empirical research carried out in 2018. The paper includes an abstract of the theoretical research of gender leadership and the social and emotional leadership competencies based on the research methodology and the results received. According to the results of the empirical research, it is possible to find matching assessments of social and emotional leadership competencies in men and women; certain significant differences exist as well. These results revealed which of the advantages possessed by female leaders tend to lie in their soft management skills: interaction, trust, as well as relationships and skills in working with people.
A Model of Domain Knowledge Content Updating Based on Management Information Interactions
Authors: Tekutov Jurij , Gudas Saulius , Denisovas Vitalijus , Smirnova Julija
Published: October 2019

The hierarchical Detailed Value Chain Model and the Elementary Management Cycle model of educational domain knowledge content updating are formally described in this paper, wherein computerized process measures are also proposed. The paper provides a method for updating the knowledge of the analyzed domain, referred to as the “enterprise domain,” based on enterprise modelling in terms of management information interactions. A method was designed, the formal DVCM and EMC descriptions of which are provided in the BPMN notation, allowing to develop a two-level (granular) model for describing the knowledge of educational domain management information interactions. In implementing this model and its algorithms in technological terms, a subsystem of enterprise knowledge has been created in a knowledge-based CASE system (computerized knowledge-based IS engineering), which performs the function of a domain knowledge database.
Peculiarities of Tour Guides’ Communication with Disabled People
Authors: Statkuvienė Daiva
Published: October 2019

Disabled people tend to go on tours more often. Neither guide training programs nor the guidebooks of arranging and doing tours include the peculiarity of working and communicating with disabled people. The features of how guides communicate with disabled people are researched in the paper. The peculiarities of doing a tour for physically, visually, auditorily, and mentally disabled people are found out. The sources of scientific literature and the standard of disabled people service are analyzed; conclusions are presented on how important it is for a guide to recognize clients’ disabilities, understand the culture of communicating with disabled people, and discover the most suitable methods of communication. The service of disabled tourists that satisfies their needs, ensures their dignity, integration, self-reliance, and equal rights should be the aim of any professional tour guide. This paper lays out some recommendations for the guide training program on including instructions for communicating with disabled clients.
The religious dimension reconstruction of the public sphere in modern theories of sociology of religion
Authors: Vashrova Natalia
Published: October 2019

The article describes the features of studying interaction between religion and society in contemporary sociology of religion. In particular, author presents theories, studying the transformation of religion, its adaptation to modern conditions, the emergence of new forms of interaction with political and public. Conducted is the review of Ukrainian sociologists’ elaborations in the interpretation of the religion’s role and place in modern society. The author also focuses on the possibilities of applying the approaches of Western sociology of religion for the conceptualization and the study of religious life in Ukraine.
The image of the 'powerful': methodology and results of the empirical content-analytical research
Authors: Yuzva Liudmyla
Published: October 2019

The author suggests design and analysis of the image of 'powerful' based on the certain parameters (socio-demographic characteristics, gender, race, health, education, marital status, number of children, occupation, age, sexual orientation, hobbies, titles and ranks), which were obtained by empirical content-analytical research.
Socio-economic consequences of protectionism for the Ukrainian economy (the end of 19th – the beginning of 20th centuries)
Authors: Bodnarchuk Tetiana
Published: October 2019

The article dwells upon the coverage of the issues of the influence of government policy of protectionism on the economic development and public socialization of the Ukrainian lands in end of 19th and the beginning of 20th century. Some long-term effects of the state paternalism for the domestic large-scale industry, small-scale manufacturing, agricultural production, domestic and foreign trade, etc. are revealed.
The main reasons of ineffectiveness of the domestic capitalist economy, generated by the active implementation of protection policy, are substantiated.
The Use of Nonnutritive Sweeteners in Children
Authors: Baker-Smith Carissa M. , de Ferranti Sarah D. , Cochran William J. ,   COMMITTEE ON NUTRITION, SECTION ON GASTROENTEROLOGY, HEPATOLOGY, AND NUTRITION, Abrams Steven A. , Fuchs George J. , Kim Jae Hong , Lindsey C. Wesley , Magge Sheela N. , Rome Ellen S. , Schwarzenberg Sarah Jane , Lightdale Jenifer R. , Brumbaugh David , Cohen Mitchell B. , Dotson Jennifer L. , Harpavat Sanjiv , Oliva-Hemker Maria M. , Heitlinger Leo A.
Published: October 2019

The prevalence of nonnutritive sweeteners (NNSs) in the food supply has increased over time. Not only are more children and adolescents consuming NNSs, but they are also consuming a larger quantity of NNSs in the absence of strong scientific evidence to refute or support the safety of these agents. This policy statement from the American Academy of Pediatrics is intended to provide the pediatric provider with a review of (1) previous steps taken for approved use of NNSs, (2) existing data regarding the safety of NNS use in the general pediatric population, (3) what is known regarding the potential benefits and/or adverse effects of NNS use in children and adolescents, (4) identified gaps in existing knowledge and potential areas of future research, and (5) suggested talking points that pediatricians may use when discussing NNS use with families
Política y biopolítica: una aproximación desde Foucault, Agamben y Rancière
Authors: Fajardo Christian
Published: October 2019

Este artículo busca esclarecer conceptualmente la diferencia entre política y biopolí-tica. Para alcanzar este objetivo, el texto explora la preocupación de Foucault por determinar cómo la vida biológica empieza a ser conducida por las técnicas modernas de gobierno. Enseguida pone en evidencia la preocupación de Agamben por mostrar que la biopolítica es la forma metafísica por excelencia que configura lo político en Occidente. Finalmente, y con la ayuda de Rancière, se muestra que la biopolítica no es tanto una forma metafísica que produce nuda vida, sino una forma del reparto policial de lo sensible que reacciona al escándalo que trae consigo la política.
Rivera Cusicanqui, S. (2018). Un mundo ch’ixi es posible. Ensayos desde un presente en crisis. Buenos Aires: Tinta Limón. 176 pp.
Authors: Gómez-Muller Alfredo
Published: October 2019

En América Latina, la socióloga e historiadora Silvia Rivera Cusicanqui ha sido una de las primeras en pensar el problema de la persistencia de ideas y prácticas coloniales en las regiones del continente que fueron antiguamente colonizadas por España y Portugal. En su último libro Un mundo ch’ixi es posible. Ensayos desde un presente en crisis nos invita a pensar la posibilidad de un mundo ch’ixi, ante todo el de Bolivia, sociedad donde ella vive y que mejor conoce. Los cuatro ensayos y la entrevista que componen el libro se refieren en lo fundamental a la historia social, cultural y política de ese país, en particular de su mundo andino; asimismo, contienen elementos que pueden resultar válidos para el estudio de otras realidades latinoamericanas e incluso de otras partes del mundo.
Presentación
Authors: Múnera Leopoldo , Caicedo Andrés , Prieto Sylvia , Sáenz Marya
Published: October 2019

Uno de los ejes teóricos y analíticos de este número es la pregunta por el sentido de la política y lo político. Este interrogante se articula con la preocupación por comprender la importancia que tienen los lugares físicos o simbólicos (las epistemologías, las racionalidades, las disposiciones afectivas, los lenguajes…) desde donde se habla y se producen estas dos dimensiones de la vida social. En otras palabras, al investigar el sentido de la política y lo político, este número también se preocupa por explorar los ámbitos de enunciación desde los cuales ambas dimensiones han sido pensadas y han adquirido forma. Recorrer cada uno de los lugares geográficos, históricos, epistémicos o culturales desde donde la política y lo político han emergido como asuntos indispensables para la vida en común, sería una labor inmensa, por no decir interminable. De igual manera, resultaría imposible en estas páginas cartografiar dicho recorrido, es decir, caracterizar cada uno de los ámbitos explorados, dibujar sus fronteras, delinear sus posibles zonas de encuentro o trazar sus puntos de ruptura.
Biológiai terápia szisztémás alkalmazása a szemészetben
Authors: Benyó Fruzsina , Farkas Alexandra , Horváth Hajnalka , Nagy Zoltán Zsolt , Szepessy Zsuzsanna
Published: October 2019

Abstract:

We present herewith cases of non-infectious uveitis with biological treatment where the ocular complaints were the initial symptoms indicating a multi-organ autoimmune disease. The first case was a patient with panuveitis and Vogt–Koyanagi–Harada disease, the second case was also a panuveitic patient with sarcoidosis and the third case was a patient with intermediate uveitis and inflammatory bowel disease. In all cases, emerging new, biological therapy (adalimumab) was necessary to achieve permanent inactive period of uveitis and the autoimmune disease. Introducing systemic biological treatment (adalimumab) in ophthalmology is crucial in the therapy of immune-mediated, non-infectious uveitis in order to preserve visual acuity. Orv Hetil. 2019; 160(44): 1744–1750.
EXTRACTION OF LIGNIN FROM SUGARCANE BAGASSE BY DEEP EUTECTIC SOLVENTS (DESs)
Authors: Thao Nguyen Bui Thi , Tru Nguyen Nhi , Minh Hoang Thai Ngoc , Duong Nguyen Hoang , Cuong Tran Manh
Published: October 2019

Lignin plays a crucial role as a structural material of plant cell walls and is also known as a significant renewable resource that has the potential to be a raw material for producing high value chemicals. The article aimed to research on the extraction of lignin from sugarcane bagasse by environmental method using deep eutectic solvents (DESs) containing choline chloride and formic acid. In the process, lignins dissolved in DESs were isolated from the solution by dilution with water and ethanol. The obtained lignin samples were characterized with UV - Vis (Ultraviolet – visible spectroscopy), FT-IR (Fourier-transform infrared spectroscopy), GPC (Gel permeation chromatography), and 1H-NMR (Proton nuclear magnetic resonance). The initial results showed that the extracted lignin obtained adequately distinct functional groups and the weight average molecular mass of the lignin was about 28265 g/mol.
EFFECT OF CERIUM OXIDE ON PROPERTIES OF LOW-PROTEIN VULCANIZED NATURAL RUBBER
Authors: Nguyen Thanh Thi Le , Cao Viet Xuan , Nguyen Linh Vu Viet
Published: October 2019

Natural rubber (NR) latex is considered as a “green material” because of its natural origin and a sustainable choice as well as it minimizes environmental impacts so that it has become an integral part of our daily lives. However, natural latex may contain allergenic proteins that need to be removed and this process affects the properties of vulcanized materials. In this study, an attempt has been made to incorporate cerium oxide (CeO2) into low-protein NR latex and effect of CeO2 content on the mechanical properties of the CeO2/ vulcanized rubber composite films such as tensile modulus 100% (M100), tensile modulus 300% (M300), tensile strength, tear strength was investigated.  The results show that the properties of low-protein NR films were stable after 48 hrs of incubation. In particular, the mechanical properties were remarkably improved while increasing CeO2 content from 2 to 4 phr. In addition, aging resistance (AR) ability by evidence of thermal degradation and Q-sun environment test in the presence of CeO2 (4 phr) is excellent whilst AR coefficient is closest to zero. This research has provided an initial prospect of the use of rare earth oxide to produce commercially valuable products from the natural rubber resources in Vietnam.
Propuesta para aumentar la competitividad de los productores de Uchuva de Norte de Santander mediante la diversificación de su oferta exportable.
Authors: López-Cárdenas Anyuri , Velandia-Paredes Yulieth Carolina , González-Verjel May Stefanny
Published: October 2019

Diseñar una propuesta para la proyección y diversificación de productos a base de uchuva por medio del estudio de lasnecesidades de los consumidores internacionales, para el aprovechamiento por parte de los productores del departamento Norte de Santander.Metodología Investigación no experimiental, Mixta, descriptiva, recolección de datos participación de 30 productores de Uchuva del municipiode Cácota del departamento Norte de Santander. Instrumentos de recolección de datos, encuestas sobre procesos de siembra, cosecha yposcosecha de la uchuva. Entrevista sobre tendencias mundiales de consumo y las oportunidades que los mercados internacionales ofrecen aeste producto, Observación (visitas de campo) frente calidad e inocuidad y los diferentes procesos de producción de la uchuva, y revisióndocumental de tendencias mundiales de consumo, para la diversificación de la oferta del producto, finalmente se cruzó en Matriz Foda.Validezdel estudio fue de carácter interno, análisis de la información en apoyo de spss y atlas ti. Conclusión. En el municipio de Cácota del departamentoNorte de Santander se aplican las buenas prácticas agrícolas en su proceso productivo, las tendencias de consumo actuales es variedad deproductos de alimentación saludable y natural, podría diversificar en tres productos a base de uchuva por medio de su transformar de forma quepueda ser comercializada con un valor agregado para el aumento de la competitividad del sector nacional e internacional.
El e-learning como un recurso de desarrollo educativo
Authors: Nieto Sánchez Zulmary Carolina
Published: October 2019

Las Tecnologías de la Información y de la Comunicación (TIC) tienen un gran potencial en todos los ámbitos de la educación, desde básica a universitaria, incluyendo educación continua y capacitación técnica, ya sea presencial o a distancia. El avance de las TIC es de particular significación para la educación superior, porque ella se caracteriza por ser un sistema en el cual se gestionan exclusivamente datos, informaciones y conocimientos. La educación superior, a través de sus funciones de enseñanza, investigación y extensión, es una compleja organización orientadas al uso, generación y difusión del conocimiento; por ello, es natural pensar que unas tecnologías especialmente destinadas a gestionar el conocimiento y a comunicarlo tengan amplia significación para la educación superior.
Aproximaciones conceptuales del aprendizaje organizacional.
Authors: Rivera-Porras Diego
Published: October 2019

El presente artículo corresponde a la revisión documental realizada con el propósito de analizar las aproximacionesconceptuales del aprendizaje organizacional. Para este análisis se recolectaron cincuenta referencias científicas en un periodo no mayor a cincoaños de publicación. Como principales hallazgos se encontró el concepto conjunto del aprendizaje organizacional como un proceso dinámicoque involucra a la empresa y sus colaboradores, así mismo la efectividad de este proceso afecta el rendimiento empresarial y algunos procesosinternos como lo son la inducción y capacitación.
Profesionales del nuevo milenio: llamados a ser actores de cambio.
Authors: Carrillo-Sierra Sandra Milena
Published: October 2019

Una vez el ser humano reconoce sus habilidades e intereses profesionales, se enlista en la formación profesional y es en ayuda de su alma mater que forja los conocimientos científicos para el desarrollo de su profesión, en el mundo laboral, de allí, la importancia de los modelos pedagógicos en la educación superior, que permitan el desarrollo de las competencias profesionales y personales, para hacer de los egresados personas inclusivas, resilientes, emprendedoras y con vocación de servicio.
Adapting futures scenarios to study UK household energy demand
Authors: Banchs-Piqué Miquel , Hutchinson David J , Becerra Victor M , Gaterell Mark
Published: October 2019

Greenhouse gas emissions originating from the built environment play a significant role towards climate change. Carefully planning the future of the building sector is key to mitigating these emissions. Addressing this problem by using a predictive approach may miss possible futures that cannot be anticipated. Using explorative scenarios to perform futures analysis helps widen the range of futures taken into account, which minimises this risk. Tools that use scenarios to help study the resilience of sustainable solutions for the UK urban environment are already available. However, they do not facilitate in-depth analysis of future household energy demand. This paper considers how one such tool, ‘Designing Resilient Cities’ (DRC), could be modified appropriately. It includes (a) a series of indicators representing factors affecting the energy demand in dwellings and (b) their characteristics for each scenario to complement the narratives in DRC. As a case study to validate these additions, the resilience of a recommendation to decrease domestic electricity consumption is evaluated.
The South African Journal of Chemistry 1918-2018: A Celebration
Authors: Ford T. Anthony , Kruger Hendrik G , Loyson Peter
Published: October 2019

In celebration of the centenary of the first publication of the South African Journal of Chemistry, the history of the Journal is traced, with reference to the personalities involved in its development and its relationship with the South African Chemical Institute. The impact of online publishing on the format of the Journal and the ways in which the handling of submitted manuscripts have changed over time are discussed. Some statistics are presented illustrating the changing topicality of the various chemistry disciplines over time, as well as the expansion of the potential pool of authors arising from the internationalization of the scientific publishing field. Reference is also made to the quantitative measures by which the integrity and international acceptance of the Journal are judged. Keywords: History, personalities, online publishing, statistics.
Isolation of single nuclei from postmortem fresh frozen human brain and immunostaining for NeuN v1
Authors: Otero-Garcia Marcos , Cobos Inma
Published: October 2019

- Protocol based on Krishnaswami et al., Nat Protoc. 2016, 3:499-524 - Used routinely in our lab for the isolation of single nuclei from fresh frozen postmortem brains from subjects with neurodegenerative disorders and healthy controls for single-nucleus RNA-seq - Works also for isolation of nuclei from fresh frozen mouse brains - Used for isolation of all nuclei or antibody-enriched populations (i.e., NeuN+ nuclei) - We always perform and strongly recommend FACS if used for single-nucleus RNA-seq
Isolation of single somas from postmortem fresh frozen human brain and immunostaining for AT8 and MAP2 v1
Authors: Otero-Garcia Marcos , Cobos Inma
Published: October 2019

- Protocol optimized to isolate single neuronal somas with cytoplasmic protein aggregates from postmortem fresh frozen brain - Works for the isolation of neuronal somas with neurofibrillary tangles from Alzheimer disease's brains - Note that cell membranes are highly disrupted in tissues that were previously frozen. Thus, cytoplasmic transcripts are largely lost. This protocol is therefore useful for the isolation of specific cell populations using antibodies against cytoplasmic antigens, but not for the profiling of cytoplasmic mRNA.
Changes in sugar-sweetened beverage purchases one year after Chile’s front-of-package warning labels and marketing restrictions: a pre-post analysis v1
Authors: Smith Taillie Lindsey , Reyes Marcela , Colchero Arantxa , Popkin Barry , Corvalán Camila
Published: October 2019

Brief Summary: In April 2012, the Chilean Senate passed the country-wide National Law of Food Labelling and Advertising, which has 3 major components: (i) point-of-food purchase labelling to improve consumer information through front-of-package (FOP) easy-to-understand labels, including specific messaging around sugars, saturated fats, sodium, and energy, (ii) complete restrictions on marketing and advertising of unhealthy foods to children under age 14y over an array of media and hours of coverage that cover a great deal of media time, and (iii) complete restriction of sale/offer (i.e. kiosks, cafeterias, school feeding programs) of unhealthy foods in schools and nurseries. The implementation began on July 1, 2016, and over a 3-year period becomes increasingly stringent with regards to the nutritional quality of food products. The aim of this study is to assess the changes in beverages’ purchase in Chilean households after the implementation of the first phase of the Chilean Law of Food Labelling and Advertising entered in force. For this purpose, we will use purchase data from Kantar World Panel, from 2014 to December 2017. We hypothesized that compared to the counterfactual (what would have happened with beverage purchases had the regulation not be implemented based on pre-regulation trends i.e. comparing the predicted post-regulation purchases based on the pre-regulation trend with observed post-regulation purchases), post-regulation: Overall, the total volume, sugar, and calories of regulated beverages will decline in the post regulation period. Volume of beverages in the baseline period that were regulated in July 2016 and remained regulated in the post-regulation period will decline. Volume of beverages in the baseline period that were regulated in July 2016 but became unregulated in the post-regulation period will increase. Calories and sugar of regulated beverages that remained regulated will decrease. Calories and sugar of regulated beverages that became unregulated will decrease. Households with a higher level of household head education will show larger declines in regulated beverage purchases than lower-educated households. Households with children <14y will show larger declines in regulated beverage purchases than households without children. Volume, calories, and sugar of unregulated beverages will increase. Calories and sugars of total beverage purchases will decline. Volume of total beverage purchases will not change.
Question Asking and the Common Good: A Hermeneutic Investigation of Student Questioning in Moral Configurations of Classroom Practice
Authors: Gong Susan P. , Yanchar Stephen C.
Published: October 2019

This qualitative study (based on a hermeneutic moral-realist interpretive frame (Yanchar & Slife, 2017)) explored question asking as it unfolded in the everyday practice of being a student in a graduate course on design thinking (with an emphasis on design in education). Findings are presented as four key tensions that occurred within the complex classroom setting under investigation: “theory and overlapping practices,” “convergence and divergence,” “participation and reticence,” and “give and take.” Overall, these thematized tensions point to a dynamic interplay between student agency and the common good of the class. These findings have significant implications for understanding student questioning experiences and the study of classroom interactions.
The First Year in Teaching: Changes in Beginning Teachers’ Visions and Their Challenges
Authors: Ergunay Onur , Adiguzel Oktay Cem
Published: October 2019

The present study examines both the changes in beginning teachers’ visions and the challenges they face during their first year experience in teaching. A basic qualitative research methodology was used, and the data were collected through semi-structured interviews and a questionnaire that included open-ended questions from eighteen beginning teachers who started teaching in public schools in Eskisehir, Turkey. A vision-oriented teacher education model provided the conceptual framework for identifying the changes in participants’ visions. The challenges were also emerged through inductive analysis of the data. The findings provide some evidence of considerable changes in beginning teachers’ visions and challenges in their first year teaching experience. They also present evidence for the significance of first year teaching experience in beginning teachers’ visions. The study also highlights the crucial role of learning through experience in the teaching profession. In the end, some further research trajectories on teacher education, particularly changes in visions and challenges are suggested.
“It Requires Interest, Time, Patience and Struggle”: Novice Researchers’ Perspectives on and Experiences of the Qualitative Research Journey
Authors: Kalman Mahmut
Published: October 2019

This study aimed at exploring novice researchers’ experiences of and perspectives on the qualitative research journey and determining the difficulties tackled and strategies developed while conducting qualitative research. The study was an interview-based qualitative case study involving nine graduate students in education as the participants. The data were collected between 2017 and 2019 at a state university located in Southeastern Turkey. The content-analyzed data revealed several findings about the research topic, indicating that the novice researchers considered the qualitative research journey as daunting and overwhelming, but pleasurable and satisfying. Despite scholarly development and lessons learned in the process, the researchers confronted with several difficulties concerning data collection, analysis and interpretation, recruitment and developing rapport, representation of findings, and the research process as a whole. They developed personal and external support strategies during the research journey. The metaphorical perceptions portrayed the elusive and distinctive nature of qualitative research.
Food Activism and Citizens’ Democratic Engagements: What Can We Learn from Market-Based Political Participation?
Authors: Lorenzini Jasmine
Published: October 2019

Food democracy calls for a democratization of the production, distribution, and consumption of food. Researchers and lay citizens are showing a growing interest for initiatives associated with food democracy, yet the specific democratic ideals and involvements that make up food democracy have gained limited attention. Many forms of participation associated with food democracy are market-based, such as buying organic food or joining community-supported agricultural projects. Research shows that market-based logics influence multiple spheres of life and threaten democratic ideals. However, scholars working on political participation have not yet analyzed the influence of market-based logics across forms of participation. This article analyses the action repertoire of food democracy to assess the influence of market-based logics on different forms of food activism. It builds on four critiques of market-based politics to question the relationship between different forms of participation and the market. It addresses three research questions: Which forms of political participation do citizens use to democratize the food regime? Which conceptions of democracy relate to these different forms of food activism? Which critiques of market-based politics apply to different forms of food activism? The article highlights the widespread risk of unequal participation, crowding out, commodification, and state retreat across forms of participation used to democratize food regimes. This study provides insights into the types of democratic renewal being experimented with in the framework of food democracy as well as their limits.
How Civil Servants Frame Participation: Balancing Municipal Responsibility With Citizen Initiative in Ede’s Food Policy
Authors: Van de Griend Joëlla , Duncan Jessica , Wiskerke Johannes S. C.
Published: October 2019

Contemporary governance is marked by increased attention for participation of non-governmental actors (NGAs) in traditionally governmental activities, such as policy-making. This trend has been prevalent across food policy processes and reflects a key feature of food democracy. However, the role of governmental actors in facilitating and responding to this participation remains a gap in the literature. In this article, we ask how civil servants frame the participation of NGAs in policy processes. Drawing on ethnographic research, we introduce the case of civil servants working on an urban food policy for the municipality of Ede (the Netherlands). Our analysis uncovers two competing frames: 1) highlighting the responsibility of the municipality to take a leading role in food policy making, and 2) responding reflexively to NGAs. The analysis provides insights into how the framing of participation by civil servants serves to shape the conditions for participation of NGAs. It further sheds light on related practices and uncovers existing tensions and contradictions, with important implications for food democracy. We conclude by showing how, in the short term, a strong leadership role for civil servants, informed by the responsibility frame, may be effective for advancing policy objectives of the municipality. However, the reactive frame illustrates that civil servants worry this approach is not effective for maintaining meaningful participation of NGAs. This remains a key tension of participatory municipal-led urban food policy making, but balancing both municipal responsibility and an open and reactive attitude towards the participation of NGAs is useful for enhancing food democracy.
Land Investments, Food Systems Change and Democracy in Kenya and Mozambique
Authors: Dekeyser Koen
Published: October 2019

In Africa, food systems intersect with dynamics such as demographic growth, urbanisation, and climate change, as African food systems are key drivers of livelihood provision, development, and human-environment interactions. The governance of African food systems shapes how food systems are changing as a response to these dynamics, which will have important social, economic, and ecological impacts for generations of Africans. This article positions large land investments in food system changes in central Kenya and northern Mozambique based on a large-scale household survey and interviews, and uses these findings to debate the concept of food democracy. Large land investments contributed to more modern food systems, which impacted land availability, household’s engagement in agriculture, and supply chains. These changes shifted power and control in local food systems. But even in the ‘extreme’ example of land investments, local perspectives challenge what could, and could not, be included in a democratic food system.
Empowering People—Democratising the Food System? Exploring the Democratic Potential of Food-Related Empowerment Forms
Authors: Bornemann Basil , Weiland Sabine
Published: October 2019

The current food system, characterised by considerable concentrations of economic and political power, is widely regarded as undemocratic and in many respects unsustainable in its outcomes. To address the democratic deficits in the food system, empowerment has become a central claim and point of reference for actors seeking to transform the system. In fact, numerous venues and practices have emerged in recent years to develop people’s capacities to engage with food issues. These range from local food initiatives and health-food movements to food policy councils and government education policies. This article takes a closer look at the theory and practice of democratic empowerment in the food system. It explores whether and how different forms of food-related empowerment have the potential to improve the democratic quality of the food system. Based on a broad analytical understanding of empowerment that is combined with a notion of power-based complex democracy, it is argued that different forms of food-related empowerment promote the development of different types of power, which in turn are constitutive for different functions of the democratic process. From this perspective, the challenge of democratising the food system lies in linking different complementary empowerment practices into functioning configurations of complex democratic governance.