bluuebunny/crossref_metadata_2025 huggingface dataset:
Правовое регулирование института уполномоченного по правам человека в России
Authors: Маказиева З.Д.
Published: June 2022

Исторически, российская государственность сложилась в качестве полиэтничной, что предполагает федеративные отношений, а также их постоянную модернизацию. Модернизация федеративных взаимоотношений выступает в качестве основного условия, при учете того, что во всем мире постоянно происходят различные события, а также делаются попытки укрепления согласия между различными народами, имеющими свою культуру и обычаи. Ведь именно в этом и заключается одно из главных условий поддержания единства государства. Процесс формирования в регионах страны института омбудсмена весьма сложен. Определяющим фактором является отношение к нему муниципальных властей, а также политическая культура, уровень политических взглядов муниципальных представителей власти.
Субъекты семейных правоотношений
Authors: Мамашарип кызы Багдагул
Published: June 2022

В данной статье проведен анализ правового статуса субъектов семейных правоотношений в Кыргызской Республике.Ни общественные объединения, ни юридические лица, ни другое образование не могут выступать в качестве субъектов семейного права и не могут иметь семейных прав и обязанностей, присущих человеку. По итогам исследования сделан вывод, что семейная правоспособность имеет определенные особенности при сравнении с гражданской правоспособностью.
Оценка эффективности хонингования внутренних цилиндрических поверхностей
Authors: Яшков В.А. , Лазуткин С.Л. , Артамонова Т.М.
Published: June 2022

Наиболее частыми причинами геометрических погрешностей является температурные перекосы, получающиеся от плохих смазки и охлаждения во время обработки цилиндра. При этом деформации или перегрев, при хонинговании, могут быть результатом слишком высокого давления прижима хонинговальных брусков. Сопоставление технологических схем хонингования и центробежного щлифования сборным абразивным инструментом с радиально-подвижными абразивными сегментами позволяет говорить о значительной общности данных технологических способов в плане организации охлаждения инструмента и обрабатываемой поверхности. Работа посвящена обоснованию критерия оценки эффективности технологического процесса хонингования внутренних цилиндрических поверхностей при ремонте двигателей внутреннего сгорания.
Анализ способов предоставления услуг сети интернет авиапассажирам
Authors: Дикалов И.С. , Ширко А.И.
Published: June 2022

Статья посвящена анализу способов предоставления услуг сети Интернет на борту самолѐта. Выявлены преимущества и недостатки различных способов. Предлагается применение систем, использующих космические аппараты на высокоэллиптических и низких орбитах. Практическая реализация данных систем позволит уменьшить стоимость и увеличить зону предоставления услуг.
Yurt Dışında Yapılan Din ve Yaşlanma Çalışmaları Üzerine Bir İnceleme
Authors: GÜRSU Orhan
Published: June 2022

1950’li yıllardan sonra yükselmeye başlayan nüfus artış hızı, sağlık alanındaki gelişmeler ve ölüm oranlarının azalmasıyla birlikte dünya genelinde özellikle 20. yüzyılın başında hızla artmaya devam etmiştir. Yaşlanan bireyin zamanla geçirdiği biyolojik, psikolojik ve sosyal değişimler yaşlılık döneminde çeşitli problemleri de beraberinde getirmektedir. Hem yaşlılığın anlamlandırılması hem de yaşlılıkta karşılaşılan problemlerle başa çıkma çabaları yaşlılık döneminde dinin önemli bir konuma gelmesine neden olmaktadır. Nitel araştırma desenlerinden derleme olarak tasarlanan çalışmada ülkemizdeki yaşlılık çalışmalarına ilham olması için yurt dışında din ve yaşlanma konusunda yapılan çalışmaların konu eğilimleri ve yöntemsel içeriklerinin tespit edilmesi amaçlanmıştır.

Ölçüt örnekleme tekniğiyle belirlenen Din, Maneviyat ve Yaşlanma Dergisinde son 10 yılda yayınlanan 203 çalışmalanın verileri doküman incelemesiyle elde edilmiştir. Elde edilen veriler bibliyometrik analiz ve içerik analizi yapılarak çeşitli başlıklar altında sınıflandırılmıştır. Sonuç olarak Din, Maneviyat ve Yaşlanma Dergisi’nde son 10 yılda yayınlanan makalelerin konu dağılımlarını tespit etmek için yapılan analizlerde çalışmaların en fazla (%12,8) doğrudan maneviyat konusunda yapıldığı ve en çok atıf alan konunun maneviyat olduğu tespit edilmiştir. Yöntemsel açıdan çalışmaların %35,5’i nitel, %23,6’sı nicel, %4’ü karma yöntemle yapıldığı ve %35,5’inin de teorik çalışma olduğu tespit edilmiştir.
Orta Çağ Batı Hıristiyan Manastırlarında (6-12. yy.) Manevi Okuma Kültürü: Lectio Divina
Authors: GÜZELDAL Yasin
Published: June 2022

Bu araştırmada özellikle Batılı bir manevi uygulama olan lectio divina'nın ana unsurlarından bahsedilmeye çalışılmıştır. Kutsal Kitap dışında okumaya çok fazla önem verilmeyen erken dönem Hıristiyan manastırcılığının ortaya çıktığı çöl keşişliğinden yerleşik manastır düzenine geçiş sürecinde birçok yeni uygulamalar ortaya çıkmıştır. Okuma alışkanlığı da yerleşik manastırlara geçildikten sonra manastırın vazgeçilmez unsurlarından biri haline gelmiştir. Bu terimin manastır literatürüne girmesi ise onu bir tür manastır disiplini olarak günlük manastır takvimine dahil eden Aziz Benedikt'e (MS 480-547) kadar uzanmaktadır. Manastırlarda uygulanan lectio uygulaması, bu okuma eyleminin içeriğinin ne olduğu, süresinin ne kadar olduğu ve nasıl tatbik edilmesi gerektiği gibi birtakım soruları da beraberinde getirmiştir. Bununla ilgili olarak, özellikle Aziz Benedikt'in de çağdaşı olan Cassiodorus'un manastır literatürüne yaptığı katkılar ve manastır okulu ideali önem arz etmektedir. Ayrıca çalışmada, lectio ile doğrudan ilişkili olması ve bilginin muhafazasının sağlanıp sonraki nesillere aktarılması açısından önemli bir yeri bulunan manastır kopyalama faaliyetleri hakkında da bilgi verilmiştir. Buradan hareketle, manastır kütüphanelerinde okunan Kutsal Kitap ve dini eserlerin dışında kalan pagan literatürüne dair, erken dönemden 12. yüzyıla kadar manastır önde gelenleri tarafından yapılan yorumlar incelenmeye çalışılmıştır. Lectio divina, Roma Katolik Kilisesi'ne bağlı olan manastırlar arasında popülerlik kazanmış ve 12. yüzyıla gelindiğinde II. Guigo tarafından bugün bilinen hali olan dört aşamalı okuma sürecine dönüşmüştür. Bu dört aşamalı sürecin detayları ise son bölümde verilmeye çalışılmış ve sonuç bölümünde yapılan değerlendirmeler ile araştırma sonlandırılmıştır.
Analogies used in presenting genetics in senior secondary school biology textbooks in Nigeria
Authors: Ojediran Isaac Ayodele , Oyinwola Oluseun Esther , Agboola Omowunmi Sola
Published: June 2022

The field of genetics is often believed as a subject or a topic in biology that is difficult to learn and comprehend. The study aimed to identify the analogies used in the presentational format in illustrating genetics in selected biology textbooks in Osun State, Nigeria. The study adopted a descriptive survey research design. The population for the study comprised all the nine biology textbooks presently recommended by the Osun State Ministry of Education for implementing the biology curriculum. The study sample comprised six out of the nine recommended biology textbooks in Osun State using a simple random sampling technique. An instrument developed by Curtis and Reigeluth titled Biology Textbook Genetics Analogy (BTGA) was adapted and was used to collect data for the study.  The study concluded that verbal analogies, simple analogies, and advance organizer analogies are the predominant analogies used in textbooks. It was also concluded that textbooks should include and balance the ratio of the different types of analogies being used.
 
Keywords: Analogy, Biology Textbook, Genetics, Senior Secondary School, Osun State (Nigeria)
Psychological states of professional anxiety and job perceptions of university students
Authors: Oralgaliyevna Oryngaliyeva Sholpan , Rizabekovna Yermentayeva Ardakh , Orazgaliyevna Iskakova Marzhan , Bolatbekovna Kadirsizova Shynar , Toktarovna Karipbayeva Shynar , Konstantinovna Akimenko Natalya
Published: June 2022

One of the areas that have an important place in the professional competence of students studying at universities is their psychological competence. Professional concerns are also included in the fields of psychological competence. It is important for students to be ready in every field to ensure their professional competence. For this purpose, in this study, it was aimed to determine the opinions of the students studying at the university on the level of professional skills. In this context, 85 students studying at the university in the 2020–2021 academic year were interviewed and their opinions on their sectoral expectations and professional uncertainties in their professional lives were taken. Before the research, official permission from the relevant institution and verbal participation approval from the students were obtained. In order to reach the research finding, four semi-structured interview questions were asked by the researcher by taking expert opinions. The results of the research were explained in detail with the content analysis method. As a result of the findings obtained from the research, it was revealed that their anxiety about the department was high, they were undecided about choosing the right department and the education they received was insufficient.

 

Keywords: Education, profession, psychological, psychological competence, student, anxiety, university;
BRiCE Project DRC and Niger: Baseline Report
Authors: Marchais Gauthier , Gupta Sweta , Brandt Cyril Owen , Justino Patricia , Leone Marinella , Marion Pierre , Matabishi Samuel , Somora Patrick Mze , Nyabagaza Pacifique , Kanyerhera Dieudonne , Kiemtoré Issa , Bazuzi Christian PolePole , Falisse Jean-Benoît
Published: June 2022

This Report presents the descriptive statistics and preliminary analysis carried out following the first phase of quantitative and qualitative data collection of the Building Resilience in Conflict through Education (BRiCE) research project in the Democratic Republic of Congo (DRC) and in Niger. Activities were led by the Institute of Development Studies, in partnership with Save the Children, with the Institut Supérieur Pédagogique de Bukavu in DRC and with the Save the Children MEAL team in Niger. The objective of the study is to further the understanding of education in fragile and conflict-affected contexts, focusing on four central research questions: RQ.1) Investigating whether, and how, exposure to and experience of violence influence teaching quality and well-being in fragile and conflict-affected contexts; RQ.2) Examining the impact of the Teacher Professional Development and Improving Learning Environments Together components of the BRiCE programme on teachers’ quality and well-being in fragile contexts; RQ.3) Examining how teaching quality and well-being influence children’s cognitive and non-cognitive outcomes in fragile and conflict-affected countries; RQ.4) Exploring how knowledge developed by teachers in conflict-affected contexts can be used effectively in policy and programming.
Bronze casting of the Vychegda Permians (based on the materials of the Lower-Vychegda Chezhtyyag burial ground)
Authors: Astakhova I. , Savelyeva E.
Published: June 2022

The paper deals with the burials of the excavation No. 7 of the Lower-Vychegda Chezhtyyag burial ground of the Vym culture of the Vychegda Perm, in which objects indicating the occupation of the population by bronze casting were found. The analytical studies were based on using optical and scanning electron microscopes. Based on the analysis of the grave goods, the belonging of these burials to women is substantiated. The conducted geochemical analysis of scrap metal found in the burials is represented by tin bronzes with lead separations, metallurgical copper, tin and silver-copper alloy. Metallurgical copper, lead-copper, zinc bronze, and tin bronze were used to manufacture adornments and household items. Convincing evidence of local bronze casting was obtained. Tin bronzes, lead and copper were produced mainly locally. Among the non-ferrous metal products, both products of local craftsmen and imported ones are presented. The similarity of the composition of non-ferrous metal and scrap metal products confirms the assumption that the burials in question belong to female casters, whose main field of activity was bronze casting.
The Geolex Biogeosorbent: practical application of technologies
Authors: Schemelinina T. , Anchugova E. , Kotova Ol'ga
Published: June 2022

The oil and gas industry plays a key role in the Russian economy. However, its risks of environmental impact are among the highest in modern production industries. The need for the fastest recovery of territories requires a prompt elimination of consequences of soil pollution with oil. This might be achieved by an extensive complex of technologies, including biotechnological product application. This study examined contaminated soils from experimental industrial sites of the Komi Republic, Yamal-Nenets Autonomous District, Khanty-Mansiysk Autonomous District. Practices accelerating the processes of soil restoration included the application of the Geolex biogeosorbent composed of a glauconite-bearing rock and immobilized oil-degraders of the BIOTRIN biopreparation. The biotechnologies embodied enhanced the processes of dehydrogenation and oxidation of oil and petroleum products. By the end of the experiment, the dehydrogenase activity of the soils recultivated decreased, which indicated the progressive succession. The efficiency of pollutant removal at pilot sites was 68—95 % in 60 days.
Parents' experiences of work-family conflict: Does it matter if coworkers have children?
Authors: Schulz Florian , Reimann Mareike
Published: June 2022

Objective: To examine how the perception of work-family conflict relates to the share of parents in women's and men's direct coworking environments.
Background: The idea of relational demography posits that individuals' relative positions within their coworking environments have an impact on their wellbeing. Depending on women's and men's parenthood status and the corresponding (dis-)similarity compared to their colleagues, this idea was applied to the perception of work-to-family and family-to-work conflicts.
Method: Time-based and strain-based work-to-family and family-to-work conflicts were analyzed by gender and parenthood with random effects panel regression models using longitudinal data from the LEEP-B3-survey, a large-scale linked employer-employee survey from Germany (2012/2013 and 2014/2015; 2,228 women and 2,656 men). The composition of the respondents’ working groups was included as a moderating variable.
Results: Mothers and fathers of children aged 0-11 years reported higher work-to-family and family-to-work conflicts than parents of older children and childless women and men. For mothers of children aged 0-11 years, a higher share of parents in their working groups was associated with less time-based family-to-work conflict. For fathers of children aged 0-11 years, the same associations were found for overall work-to-family conflict, strain-based work-to-family conflict as well as for all dimensions of family-to-work conflict.
Conclusion: Similarity between the team members regarding parenthood seemed to reduce mothers' and fathers' perceptions of work-family conflict beyond several other characteristics of the individuals and the workplaces.
Relationships Among Self-Care, Compassion Satisfaction, and Compassion Fatigue of Nurses in Community Hospitals in the Southeastern United States
Authors: Rigdon Katherine L. , Winters Karen
Published: June 2022

The purpose of this study was to determine the relationships among self-care, compassion satisfaction, and compassion fatigue of nurses in community hospitals in the Southeastern United States. A descriptive, nonexperimental, correlational, cross-sectional research design using purposive convenience sampling with primary data analysis was utilized in this study. Statistical analysis included descriptive statistics, simple linear regression, and multiple linear regression. Statistically significant relationships were identified for self-care and compassion satisfaction and also self-care and compassion fatigue/burnout.
Caring for Self and Others: A First-Year Seminar
Authors: Dyar Kelly L.
Published: June 2022

At a public university, a nursing faculty member offered a first-year seminar course focused on helping students learn to care for self and others. A premise of the course was that learning how to learn is a form of self-care. Students explore Watson’s theory of human caring, learning how to learn, and contemplative practices. Through varied learning activities, students explored academic and wellness resources on campus. Student work demonstrated understanding of a caring theory. Incorporation of caring principles into the classroom benefits students in becoming a caring person.
A new species and taxonomic notes on the genus Combretum (Combretaceae) in Thailand
Authors:   Forest Herbarium, Department of National Parks, Wildlife and Plant Conservation, Chatuchak, Bangkok 10900, Thailand, Pattharahirantricin Nannapat , Poopath Manop ,   Forest Herbarium, Department of National Parks, Wildlife and Plant Conservation, Chatuchak, Bangkok 10900, Thailand
Published: June 2022

A new species of Combretum, C. pendulum, is described and illustrated. Taxonomic notes on typifications for C. apetalum and C. winitii, and synonymisations for C. alatum and C. quadratum are presented. A key to Thai Combretum species is also provided.
A Theoretical Analysis of the Transient Fluctuation Theorem for Accelerated Colloidal Systems in the Long-Time Limit
Authors: Lokare Yash
Published: June 2022

A quantitative description of the second law of thermodynamics in small scale systems and over short time scales comes from various fluctuation theorems. The applicability of the transient fluctuation theorem in particular to small scale systems perturbed from an initial equilibrium steady-state distribution has been demonstrated both theoretically and experimentally in several works over the past few decades. In addition, some experimental works in the past have also made successful attempts to demonstrate the applicability of the fluctuation theorem to small scale systems evolving from a certain nonequilibrium steady-state distribution over relatively long time scales. To this end, this paper seeks to demonstrate the transient fluctuation theorem for a Brownian particle confined within a power-law trapping potential by following the trajectory of the particle that itself is translating linearly along one dimension with constant acceleration in a viscous fluid. Considered herein is an idealized version of this model, in that it is assumed that the force of the trapping potential is only felt by the translating Brownian particle confined within the trap, and that this Brownian particle moves relative to the fluid molecules that are held stationary. The results presented herein show that the transient fluctuation theorem applies not only to equilibrium steady-state distributions but also to nonequilibrium steady-state distributions of an ideal colloidal system in an accelerated frame of reference in the asymptotic (long-time) limit.
Methods in Improving the Mechanical Properties and Flux of Nanofibre Membranes for Water Filtration
Authors: Hami Siddratul Sarah Binti Mohd , Nor Affandi Nor Dalila , Mohd Ahmad Faiza , Harun Ahmad Mukifza , Alam Mohammad Khursheed , Ahmad Mohd Rozi
Published: June 2022

Nanofibres have gained increasing attention due to their advantages of having a high porous structure, narrow pore size and distribution, and a high specific surface area. One of the most efficient techniques for producing nanofibres is via electrospinning. Nanofibres are currently being used in various fields, including water filtration. Although nanofibres possess the ability to filter various components, the fibres generally have a low mechanical strength that can mitigate the performance over time. Therefore, in overcoming this issue, several studies have focused on improving the strength of the nanofibre membranes for a water filtration application. This review discusses the advantages and challenges of nanofibres for water filtration membranes and summarises the methods to increase the strength of the membranes, including solvent vapour, thermal treatment, and chemical crosslinking.
Redefining the Air Defence Identification Zone in the Framework of Customary International Law
Authors: Hadisusilo Priyo , Riyanto Sigit , Purwanto Harry
Published: June 2022

The use of force against other countries is strictly prohibited and has the character of jus cogens. However, this provision is not rigidly applied in the self-defence context codified in the United Nations Charter 1945 Article 51, also in the air defence context through the existence of the Air Defence Identification Zone (ADIZ). This research discusses whether ADIZ embodies the anticipatory efforts in the framework of customary international law. The research results indicate that the determination of ADIZ is not a form of self-defence principle in Article 51, which is the realm of jus ad bellum. Moreover, the conservative self-defence prerequisites in Article 51 are no longer relevant in line with the revolutionary development of aviation and its armament technology. Therefore, ADIZ, as a state security practice, constitutes a form of anticipatory efforts within the framework of long-standing state practice as customary international law. Furthermore, the use of force for violators is limited by Article 3 bis of the Chicago Convention 1944 and the Standard and Recommended Practices.
International Human Rights Protection: The Impact of COVID-19 Pandemic on Domestic Violence
Authors: Gunawan Yordan , Irrynta Dwilani
Published: June 2022

The Corona Virus Disease 2019 (COVID-19) outbreak has impacted practically every aspect of life worldwide, particularly Asia. Governments from various States work hard to prevent and mitigate the spread by instituting multiple social distancing and lockdown measures. While those measures have been effective in containing the spread, there are other negative consequences, including the risks associated with domestic violence in the family home, whether physical, psychological, verbal, sexual, or economic violence. Subsequently, there has been a significant increase in online searches for help from intimate partner violence, according to the United Nations Population Fund (UNFPA). Moreover, the UN Women also reported that essential services, such as shelters and helplines, have exceeded their capacity. Using a normative legal research methodology that sources are obtained from secondary data, the finding shows that thousands of women living in several Asian States experienced more abuse in domestic violence and had less resilience during the pandemic. Whether national or international, the existing regulations are insufficient to prevent violence and protect victims. Thus, remote services in various sectors, including social, health, and justice, must be further developed and institutionalized by the States to overcome such issues.
The Uniform Customs and Practices (UCP 600) and Letters of Credit: How do the Jordanian Bank's Compliance Practices ?
Authors: Al-Amaren Emad Mohammed , Aletein Sultan Ibrahim
Published: June 2022

The Uniform Custom and Practice (UCP 600), has defined letter of credit as: “Any arrangement, however, named or described, that is irrevocable and thereby constitutes a definite undertaking of the Issuing Bank to honour a complying presentation. UCP 600 is subject to four main principles: Strict Compliance, Autonomy, Documents handling and virtue examination. This study aims to identify the fundamental principles governing letter of credit operation under the Jordanian Banks practice. Through a qualitative and doctrinal legal approach, this study analyses the organization of UCP 600 regarding the principle governing L/C and the extent to which Jordanian banks adhere to the principles of UCP 600. It also examines, via case approach the Jordanian court's approach towards this matter. The findings reveal that the Jordanian banks (Conventional and Islamic) with 100% are fully committed to the UCP. Moreover, this study also has found that Although Jordanian legislators did not regulate letters of credit operations under the commercial law, it can be noticed, based on the commercial law, that the autonomy principle is applicable in Jordan, even if it is applied in a different context.
Pengembangan Bahan Ajar Berbasis Teks al-Barzanjī untuk Peningkatan Hasil Belajar Bahasa Arab Siswa
Authors: Nurlatifah  , Abdurrahman Maman , Nursyamsiah Nunung
Published: June 2022

This research is motivated by low understanding of students at Al-Barokah Islamic boarding school, Bandung, in the knowledge of al-Barzanjī text on Madārij al-Ṣu‘ūd book. Therefore, using a stylistic analysis approach, the researcher developed Madārij al-Ṣu‘ūd teaching materials with al-Barzanjī text teaching materials. The method used in this research is Research and Development with ADDIE model. This study aimed to determine: (1) the steps for developing teaching materials; (2) the results of the field trial of teaching materials. Based on the study results, it can be seen: (1) the average result of the pretest for the experimental class is 48.33, and the control class is 50.83; (2) the average post-test result for the experimental class was 86.66, and the control class was 59.16; (3) the results of the N-Gain Score test showed an increase in the experimental class of 0.73 in the high category. In comparison, the increase produced by the control class is 0.12 in the low category. In conclusion, developing Fatḥ al-Bayān as a teaching material can improve students' understanding of the al-Barzanjī text. Therefore, the Arabic language skills possessed by students are increasing.
Sistem Penunjang Keputusan Berbasis Aplikasi Java Pada Proses Produksi Pembibitan Benih Ikan Air Tawar di Desa Talang Kemulun
Authors: Dasmita Rosy
Published: June 2022

Balai Benih Ikan (BBI) Lokal Talang Kemulun merupakan salah satu unit kerja struktural yang membantu Dinas Perikanan Kabupaten Kerinci dalam melaksanakan pembangunan perikanan terutama dalam memenuhi kebutuhan benih ikan. proses produksi pembibitan benih  ikan air tawar di Balai Benih Ikan (BBI) Lokal Talang Kemulun yang didominasi oleh ikan  Mas, Semah, Nila Merah, Nila Hitam, Medik, Koan dan Betok. Jenis-jenis tersebut menyumbang lebih dari 80% dengan jumlah ikan kurang lebih 7,250,000 ekor dari total produksi ikan air tawar, tetapi karena perbedaan permintaan yang berubah-ubah maka  petani dalam proses produksi pembibitan benih ikan air tawar harus selalu mempertimbangkan jenis ikan yang menguntungkan dalam proses produksi pembibitan benih ikan. Penelitian ini diimplementasikan dengan program aplikasi Java yang digunakan untuk proses Perancangan Sistem Penunjang Keputusan Menentukan Jenis Ikan Air Tawar Yang Cocok Untuk proses produksi jenis ikan air tawar. Hasil penelitian menunjukan sistem yang dirancang dapat membantu para petani ikan dalam menentukan jenis ikan mana yang cocok untuk diproduksi pembibitan benih.

 

 

Kata Kunci— Sistem Pengambilan Keputusan, Java, Pembibitan Ikan
The anti-integrity activity of eugenol on inflammatory markers of chronic atherosclerosis
Authors: Karuppasamy Venkadeswaran , Sekar Suresh Kumar , Kandhasamy Subramanian , Ramasamy Rajeswari , Sriniva Venkatesh , Varatharajan Varalakshmi , Ramar Suganya , Kannan Shalini
Published: June 2022

The putative anti-atherogenic, anti-oxidative, and anti-inflammatory potential of atherogenic diet-fed, eugenol-treated Wistar rats were studied. The levels of hematological parameters (ESR, WBC, and platelet count); the mean levels of nitric oxide (NO), and C-reactive protein (CRP) were investigated in serum samples. The mean ESR, platelet, and total WBC counts were all significantly higher in atherogenic diet-fed (Group II) rat when compared with normal (Group I), whereas the mean ESR, platelet, and total WBC counts were significantly lower in atherogenic diet-fed followed by eugenol treatment (Group III). The mean hepatic tissue mRNA transcript level of the gene responsible for CRP, iNOS, TNF-α, IL-1β, and NF-κB and expression of their protein levels were determined in liver tissue samples were found to be significantly higher in the atherogenic diet-fed followed saline treatment (Group II) rats than the normal fed (Group I) rats. However, in hepatic tissue samples from an atherogenic diet-fed followed by eugenol treated rats, the mean mRNA the transcript level of the gene encoding CRP, iNOS, TNF-α, IL-1β, NF-κB and their mean concentration of the protein translation were significantly lower than the values in Group II rat’s hepatic tissue, approaching near-normal levels. These results are exhibited anti-atherogenic potential in hypercholesterolemic Wistar rats due to their hypocholesterolemic, antioxidant, and anti-inflammatory effects.
Comparing Cultured Melanocyte versus melanoma in Terms of Genetic Stability and Tumorigenicity for Vitiligo patient’s treatment
Authors: Shahbazi Atefeh , Zargar Seyed Jalal , Bajouri Amir , Mohammadi Parvaneh , Aghdami Nasser
Published: June 2022

Aims
Recently cultured melanocyte transplantation has been evolved as a promising modality against extensive depigmentation in vitiligo which are resistant to conventional treatments. Here, we aimed to find the best growth media for clinical purposes and to determine the tumorigenic activity of cultured melanocytes both in vitro and in vivo.
Main methods:
Human skin melanocytes were isolated from 8 patients, cultured under various growth media till passages 6. The best growth media based on doubling time (DT) and cell counts at each passages, was determined. Also, changes in BRAF, NRAS, and HRAS genes expressions in cultured cells were assessed by real-time PCR and gene sequencing of BRAF V600E and NRAS in exons 1 and 2 as compared to melanoma cell lines. Karyotyping of the passage 6 melanocytes was done to assess the genetic stability. Cells of passages 5, 6 were subcutaneously injected into BALB/c nude mice to evaluate the risk of tumorigenesis after transplantation.
Key findings
: A mixture of MGM-M2 supplemented with a combination of melanocyte growth factors two times plus 4% fetal bovine serum (FBS), had the best results in terms of PDT and melanocyte count during passages 0 to 6. Karyotypes of melanocytes at passages 5 and 6 in all patients displayed no structural alterations in the 15 metaphase plate spreads. HRAS and BRAF gene expressions of melanocytes at passage 6 showed < 2-fold increases, while HRAS and BRAF gene expressions in melanoma cell lines were up-regulated to more than 3 and 8 folds, respectively. Furthermore, NRAS gene expression in melanocytes at passage 6, showed 5-fold change which was lower than NRAS gene expression in melanoma cell line. Gene sequencing of BRAF V600E and NRAS in exons 1 and 2 displayed no mutation. Melanocytes injected into BALB/c nude mice showed no risk of tumor formation. Also, gene sequencing of BRAF and NRAS in injected melanocytes displayed no mutation 16 weeks after transplantation.
Significance:
Our results revealed that culturing human melanocytes using standard growth media protocols, may increase the expression of specific proto-oncogenes, however will not lead to tumorigenic mutations, in vitro and in vivo.
Impact of blockchain technology on agricultural product circulation system: A simulation analysis with agent-based modelling
Authors: Wang Liukun , Qi Chunjie , Jiang Peng , Xiang Si
Published: June 2022

In the context of the Internet, the agricultural product circulation system needs to undergo corresponding changes to adapt to the modern fast-paced social system. Based on the main characteristics of blockchain technology and the summary of domestic and foreign theoretical research, this paper simulates the impacts of blockchain technology on the agricultural product circulation system. The results reveal that blockchain technology can improve the qualification rate of agricultural products and thereby ensure their quality and safety. Moreover, blockchain technology can significantly enhance the efficiency of the agricultural product circulation system, thus greatly promoting the economic benefits. Finally, the introduction of blockchain technology can effectively promotes the governance level and reduces the supervision cost of the agricultural product circulation system. These findings enrich the research on the application of blockchain technology in the management and circulation of modern agricultural products.
Structural Design and Modal Analysis of Nickel Anode Plate Handling Robot Based on Workbench
Authors: Kombo Krich Richel Mpemissi , Li Guoping , Okeli Naomi Daïna , Nguimbi Germain , Mbango-Ngoma Prince Audron
Published: June 2022

The purpose is to directly transport the nickel anode plate to the destination, so as to truly realize the purpose of delivering goods to people thus this type of handling robot is designed. Using SolidWorks and Workbench software to establish 3D model and finite element model, carry out detailed design of nickel anode plate handling robot, and carry out modal analysis on the main structure of the robot, and analyze its external excitation source. Results The mounting plate of the lifting mechanism on both sides was the main factor affecting the dynamic characteristics, and the designed handling structure would not resonate due to external excitation. Conclusion The overall structure of the handling robot is novel and the design is reasonable, which can realize the handling of nickel anode plates, and has high application value.
Ready-to-eat-cereal intake and long term body weight status among children and adolescents – results of the DONALD Study
Authors: Hornemann Stephanie , Jankovic Nicole , Perrar Ines , Längler Alfred , Hohoff Eva , Alexy Ute
Published: June 2022

The aim of this study is to analyse the association between RTEC (Ready-To-Eat-Cereals) intake and long-term changes in Standard Deviation Score of Body Mass Index (BMI-SDS) and Fat Mass Index (FMI) among children and adolescents in Germany. Overall, 4,920 3-day dietary records and anthropometric measurements of 721 DONALD (Dortmund Nutritional and Anthropometric Longitudinally Designed Study) participants (3.5–18.5 years; boys: 52%) kept in 2004–2018 were analysed using polynomial mixed-effects regression models. There was no statistically significant association between RTEC or RTEC meal intake and BMI-SDS as well as FMI, probably due to the overall low RTEC intake.
A Tighter Lower Bound on the Capacity of Cascading Binary Deletion Channel and Binary Asymmetric Erasure Channel
Authors: Tavakoli Hassan
Published: June 2022

The authors have requested that this preprint be removed from Research Square.
The role of the blood on the heterotopic ossification of the injured tendon through PI3K/AKT signaling pathway
Authors: Chen Xuri , Yang Yuwei , Gu Yuqing , Yi Junzhi , Wu Hongwei , Bao Fangyuan , Wang Jiasheng , Wang Ying , Tian Mengya , Wu Zhonglin , Xie Yuanhao , Heng BoonChin , Liu Hua , Yin Zi , Chen Xiao , Zhou Jing , Ouyang Hongwei
Published: June 2022

It is a common clinical phenomenon that blood infiltrates into the injured tendon caused by sports injuries, accidental injuries, and surgery. However, the role of blood infiltration into the injured tendon has not been investigated. We established a rat model in which the injured Achilles tendon was infiltrated with autologous whole blood and confirmed that blood caused acute inflammation in the short term and more severe heterotopic ossification (HO) in the long term. Then we found that blood treatment increased cell apoptosis and decreased cell adhesion and tenogenic gene expression of TSPCs. Furthermore, Blood treatment promoted osteochondrogenic differentiation of TSPCs. Next, we used RNA-seq to find that the PI3K/AKT signaling pathway was activated in blood-treated tendon tissues. By inhibiting PI3K with a small molecule drug LY294002, the expression of osteochondrogenic genes was markedly downregulated while the expression of tenogenic genes was significantly upregulated. Our findings indicate that the upregulated PI3K/AKT signaling pathway is implicated in the aggravation of tendon HO. Therefore, inhibitors targeting the PI3K/AKT pathway would be a promising approach to treat blood-induced tendon HO.
Clinical analysis of spontaneous gastric rupture in non-neonatal children
Authors: You Zhiheng , Xi Hongwei , Shi Zhengfeng
Published: June 2022

Background
Spontaneous gastric ruptures are rare in non-neonatal children, but once gastric rupture occurs, it results in rapid progression with high mortality. This study aimed to summarize the treatment experiences of 10 cases of spontaneous gastric rupture in non-neonatal children. We further investigated the etiology and treatment of spontaneous gastric rupture in non-neonatal children to reduce complications and improve efficacy.
Methods
A retrospective analysis was performed on 10 cases of spontaneous gastric rupture in children admitted to the Shanxi Children’s Hospital between January 2009 and December 2020. Abdominal radiography showed a large amount of free gas in the abdominal cavity, which confirmed gastric rupture. Therefore, surgical treatment was performed in all the patients.
Results
Of the 10 patients, 2 died postoperatively, 3 had anastomotic leakage after the second surgery following the primary operation, and 5 were treated by the primary operation. All living patients had no complications at the 1 year follow-up.
Conclusions
Acute gastric dilatation is the primary cause of gastric rupture. A large amount of free gas in the abdominal cavity on abdominal radiographs and extraction of gastric contents on abdominal puncture are valuable for diagnosing the disease. Preoperatively, fluid infusion is performed to correct shock as well as water, electrolyte, and acid-base imbalances. Gastric rupture should be treated surgically, and a simultaneous gastrostomy should be performed as it is key to ensure anastomotic healing.
Response of soil water movement to rainfall under different land uses in karst regions
Authors: Chen Lei , Zhang Keli , Zhang Zhuodong , Cao Zihao , Ke Qihua
Published: June 2022

Soil water is a critical factor closely related to hydrological and ecological processes. Owing to the complex surface conditions with heterogeneous soil thickness and abundant underlying fissures, soil water in the karst region has been a complicated issue. In this study, the dynamic changes of soil water in the vertical profile of selected grassland, farmland and bare land on a karst yellow soil hillslope in southwest China were monitored at five depths including 20, 40, 60, 80 and 100 cm with an interval of 15 minutes. Results showed that (1) there were spatial differences in the response to rainfall of the soil water content at different depths. When the rainfall amount was similar, the soil water replenishment amount and migration depth under the three land uses decreased with the rainfall intensity. In the case of light rainfall, the soil water content at 20 cm was the most sensitive to rainfall, and the response of soil water to rainfall mainly occurred at 0–40 cm. In the case of moderate and heavy rainfall, soil water could migrate down to 100 cm on grassland but less than 100 cm on farmland and bare land under heavy intensity rainfall. (2) The variation in the soil water content had interlayer differences over time. The response of soil water to rainfall in different soil layers showed multipeak fluctuations. In general, when the rainfall intensity was the same, the soil water fluctuation on grassland and farmland at the same depth was larger than that on bare land; however, the peak value of soil water decreased with soil depth. (3) Land use and the antecedent soil water content had important effects on soil water loss during the dry period. Soil water loss was faster at the beginning and before slowing down. The soil water loss rate on grassland and farmland increased with the length of the dry period but decreased gradually on bare land. These results can support the utilization and protection of soil and water resources on karst yellow soil slopes and help to understand the temporal and spatial dynamics of soil water under natural rainfall.
Effects of soil and phylogeny on sulfur and phosphorus concentrations in wild plants from Japan
Authors: Mizuno Takafumi , Kondo Daichi , Kasai Hiroto , Yamashita Jun , Ito Takuro , Murai Yoshinori , Ent Antony van der , Hashimoto Atsushi , Watanabe Toshihiro
Published: June 2022

Andosols are characterized by relatively high sulfur concentrations, but also by their suppression of phosphorus absorption in plants. We assessed the effect of soil type on the concentrations of sulfur (S) and phosphorus (P) in plants using X-ray fluorescence (XRF) analysis and plant specimens collected from Andosols and non-volcanic soils. The S concentrations in plants from Andosols are significantly high, but there is no significant difference between their foliar P concentrations. Only ∼13% of plants from Andosols were below the S deficiency level (∼0.1 wt%), but two thirds of samples were below the P deficiency level (∼0.2 wt%). The S concentrations were high in herbaceous plants, especially in plants from the Brassicaceae and Liliaceae families. Overall, the results suggest that the S concentrations in wild plants from Japan is higher in Andosols, with a low risk for S deficiency. In contrast, the effect of soil type on the P concentration in plants was small, and this may be explained because most wild plants are growing under P-limiting conditions. Finally, the analysis reveals a significantly high correlation between S and P concentrations in plants, suggesting the existence of a mechanism that controls the S and P concentration ratio.
WITHDRAWN: Electronic structure, Optoelectronic properties, FTIR, CNMR and HNMR investigation on 4-((2-hydroxy-3-methoxybenzylidene) amino)-N-(thiazol-2-yl) benzene sulfonamide molecules at different concentrations in DMSO solvent
Authors: Mamand Dyari Mustafa , Aziz Dara Muhammed , Anwer Twana Mohammed Kak , Qadr Hiwa Mohammad
Published: June 2022

Optoelectronic properties of 4-((2-hydroxy-3-methoxybenzylidene) amino)-N-(thiazol-2-yl) benzene sulfonamide molecules at different concentrations in DMSO solvent were studied. Associated with different temperatures the bandgap energies, Tauc plot, refractive index, optical and electrical properties and dielectric constant were calculated. To quantitatively analyze molecules containing known compounds, both CNMR and HNMR were estimated. The functional groups of the molecule identified in this investigation depend on Fourier- transform infrared spectroscopy (FTIR) spectroscopy. The studies were carried out with density functional theory (DFT)/ 6-311G++ (d, p) basis set and Becke’s three parameters hybrid (B3LYP) level of theory through Gaussian software. Chemical reactivity and selectivity parameters such as HOMO-LUMO, global hardness, softness, electronegativity, electrophilicity, nucleophilicity, chemical potential, bandgap energy, and electron affinity were calculated. Becke’s three parameters hybrid exchange-correlation functional (B3LYP) level was used for achieving the title molecule’s geometry optimizations.
Novel XRayNet framework for lung disease detection and infection region identification
Authors: R Nitha V , S Vinod Chandra S
Published: June 2022

Lung diseases refer to different type of disorders that cause improper functioning of lungs. The motivation of this study is in timely identification of potential lung illnesses and hence can be beneficial in better therapeutic planning. This study provides an insight into automated human lung disease detection and accurate localization of infection using chest radiographs. We propose a multi-class classification using Convolutional Hidden Markov Neural Network (CHMNN) as an effective method for identifying lung disease. The radiographs are being pre-processed initially using edge preserved median filter and contrast limited adaptive histogram equalization. The pre-processed images are segmented using the proposed adaptive otsu binarization, followed by canny edge detection, and convex hull operation. Several significant hand-crafted features such as texture, shape, orientation etc.. are extracted from the image’s segmented areas. The CHMNN classifier outperformed existing approaches in multi-class lung disease classification with a specificity of 92.5%, sensitivity of 98.1%, and an accuracy of 97.0%. In order to improve the performance of infection region detection, we propose a modified soft similarity clustering algorithm and achieved a specificity of 92.8%. To demonstrate the efficacy of the proposed mechanism, statistical simulation results are provided along with the existing approaches.
Research on cute semantic CMF design based on product digital twin principle
Authors: Geng Chuangyuan , Wu Jingjing , Jiang Wenxian
Published: June 2022

Based on the principle of digital twinning and Kansei Engineering, this paper analyzes the product modeling data to obtain the product lovely Kansei semantic reference data based on personal aesthetic needs. Firstly, the twin data of product family is collected and extracted as the training set, and then the k-Means clustering algorithm is used to cluster the twin data, and the training results are converged to obtain the virtual model database. Then, the twin data which need to be improved are compared with the data in the model database, and adjusted flexibly. According to the guidance of the data, the appearance features which are subjectively similar to the perceptual product semantics of the training system are obtained. At present, the system realizes the simulation model and algorithm of color, material and surface processing ( CMF ) twin data under the cute perceptual semantics, and constitutes a model database for ' cute-malicious ' phrase pairs under the perceptual semantic vocabulary library. Using the twin data analysis results of the same style product to assist product appearance design can optimize the design scheme and simplify the design complexity.
The effects of probiotics on the performance of pre-weaning dairy calves
Authors: Wang Liyun , Sun Honghong , Gao Haixu , Xia Yaohui , Zan Linsen , Zhao Chunping
Published: June 2022

Background: Probiotics have been used in livestock production for many years, but information on their benefits during the early life of calves is inconsistent. This study aimed to assess the effects of probiotics on the performance of pre-weaning dairy calves and identify the factors influencing their effect size. Results: Forty-nine studies were selected for meta-analysis based on the inclusion and exclusion criteria. The study qualities were evaluated using a predefined risk assessment tool following GRADE guidelines. Meta-analysis results showed that probiotics increased the body weight by 1.988 kg, average daily gain by 40.689 g/d, butyrate by 0.788 mmol/L, BHBA by 0.029 mmol/L, and IgG by 0.698 g/L, based on the strict criteria (PSMD < 0.05, I2 < 50%). In contrast, probiotics decreased feed conversion rate by 0.073, acetate by 2.815 mmol/L, AST by 4.188 U/L (PSMD < 0.05, I2 < 50%). Additionally, probiotics increased starter dry matter intake by 0.034 kg/d, total dry matter intake (TDMI) by 0.020 kg/d, IgA by 0.313 g/L, IgM by 0.262 g/L, total antioxidant capacity by 0.441 U/mL, and faecal bacteria counts by 0.680 log10 CFU/g, based on the loose criteria (PSMD < 0.05, I2 > 50%). However, probiotics decreased LDH by 78.796 U/L, MDA by 0.404 nmol/mL, and faecal score by 0.052 (PSMD < 0.05, I2 > 50%). Regression and sub-group analyses showed that probiotic strains, supplementary dosage, and method significantly affected the performance of calves. The probiotics supplied with more than 9.5 log10 CFU/d significantly increased IgA and IgG contents (PSMD < 0.05). Additionally, the compound probiotics significantly increased TDMI, IgA, and IgM (PSMD < 0.001). Furthermore, probiotics supplemented in liquid (whole milk or milk replacer) significantly increased TDMI and decreased faecal score (PSMD < 0.05), while in whole milk, they significantly increased body weight, IgA, and IgM (PSMD < 0.001). Conclusions: Probiotics improve the growth performance, feed intake and efficiency, rumen fermentation, immune and antioxidant capacity, and health of pre-weaning calves. However, the effect sizes were related to the dosage, composition, and supplementary method of probiotics.