bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimal Levels of Isoeffective Doses for Two Fractionation Modes in Glioblastoma
Authors: Datsenko P. V. , Chuguev A. S. , Gerasimov V. A. , Belikova A. A. , Kaprin A. D.
Published: April 2023

Purpose: Determination of the optimal level of a/b for the calculation of isoeffective doses in glioblastoma.

Material and methods: Two fractionation modes were studied in 141 patients with primary glioblastoma (GBM). Fractionation with the prescribed dose of 2 and 3 Gy was used alternately (a study involving a pairwise selection strategy). In addition, 34 GBM patients treated in the pilot study of the National Medical Research Radiological Centre earlier were added to the database, the total number of patients was 175 people.

Results: As of December 2022, 134 (76.6 %) of 175 treated patients had a fatal outcome. In the range of values of the coefficient a/b from 5.0 to 10.0, the indicator a/b=7.5 turned out to be the most informative. According to the criterion of overall survival, a favorable level of isoeffective dose exceeds 59.5 Gy.

The median overall survival in the group with an isoeffective dose of >=59.5 Gy was 22.3 months (95 % Cl: 17.7–26.9), in the group with a lower dose level – 10.3 months (p<0.0001).

According to monovariate analysis at an isoeffective dose of >=59.5 Gy for fractionation regimens with a prescribed dose of 2 and 3 Gy, survival rates were almost identical (p=0.745). There were no differences in overall survival in the groups with prescribed doses of 2 and 3 Gy, taking into account the use of temozolomide on the background of radiation therapy (OR=1,087; p=0.677).

In the older age group, a/b= 7.5 should be used to determine the level of isoeffective dose. The median overall survival with an isoeffective dose of >=59.5 Gy was 20.57 months (n=98; 95 % Cl: 17.7–23.4), with a lower dose level – 6.35 months (n=24; p<0.0001). In persons younger than 50 years of age, a decrease in the a/b coefficient should be expected.

Conclusion: From our point of view, the obtained data on the equivalence of regimens with a prescribed dose of 2 and 3 Gy indicate the correct choice of the level of a/b in glioblastoma and the selection of the minimum level of isoeffective dose (59.5 Gy) according to the criterion of overall survival.
China en Latinoamérica: La expansión de la ruta de la seda
Authors: Furlong y Zacaula Aurora , Netzahualcoyotzi Luna Raúl , Hernández Herrera Edwin
Published: April 2023

El posicionamiento de China como primera potencia económica mundial, ha generado una fuerte demanda de materias primas a nivel global, las cuales son indispensables para mantener su ritmo de crecimiento industrial y para la construcción de su iniciativa más ambiciosa, la Franja y la Nueva Ruta de la Seda (BRI por sus siglas en ingles). El país asiático ha buscado en otras regiones, espacios geoestratégicos para la extracción de grandes volúmenes de recursos naturales, encontrados en Latinoamérica un espacio vital para la inversión enfocada en la extracción de éstos. El objetivo de este trabajo es analizar el  impacto de la Nueva Ruta de la Seda en América Latina, debido a que desde la cumbre del CELAC en 2018, China no ha escatimado en otorgar préstamos millonarios impagables, creando también nuevas iniciativas, como el corredor bioceánico de Sudamérica.
The Usage of Communication Technology in Algerian Universities
Authors: قبيبي بن دنيا د. فطيمة , فتيحة نور الهدى د. بلبليدية
Published: April 2023

The study aims to identify the reality of using TIC in the educational process. This research has been developed by a questionnaire, taking a sample of professors from Abdel Hamid Ibn Badis University –Algeria. The study concluded; the majority of teaching staff use TIC in educational process permanently with a percentage reaches 73.52%, among the motives and reasons behind using TIC attributed to their scientific supervision towards students' researches and their guidance permanently with a percentage 44.11% , then , to respond to students' scientific concerns easily with a percentage 30.88% , then , with a meagre percentage reaches 23.52% refers to acquire the needed information to provide knowledge efficiently. It also turns out that the cognitive gratifications are the most gratifications achieved from the study sample's use of modern communication technology, therefore, we find that the content gratifications, are the ones that imposed themselves on the study sample. Most of the study sample confirms that it is mandatory and inevitable in future to use MCT in the field of higher education.
Assessing the impact of parental involvement on scaling agricultural technologies from school garden to home farm in Cambodia
Authors: Pekarcik Gracie , Ader David , Gill Tom , Richards Jennifer
Published: April 2023

Cambodia is a predominantly rural nation with a heavy dependence on agriculture, particularly smallholder rice farming systems. While several sustainable agricultural technologies have been suc­cessfully piloted on research stations or with small numbers of early adopters, questions remain on how to extend these technologies to large numbers of resource-poor smallholder farmers. The Scaling Suitable Sustainable Technologies Project (S3-Cambodia) seeks to examine pathways for scaling sustainable intensification (SI) technologies to smallholder farmers. One of the identified path­ways to scaling SI is through the education system. Cambodian youth serve as an entry point to extend target technologies to farm families through experi­ential learning opportunities in schools by estab­lishing “green labs” featuring school gardens. This research study seeks to support the desired outcomes of the S3-Cambodia project by assessing Cambodian parental involvement in their children’s lives and school activities. While students can serve as agricultural education sources for their homes and communities, there is a need to deter­mine whether relationships between children, par­ents, and schools in Cambodia are strong enough to facilitate this knowledge transfer. Primary data was collected from 178 parents whose children attend three separate high schools in three districts of Cambodia through one-on-one orally conducted surveys. These were supplemented by key inform­ant interviews of selected parents, teachers, and principals at each high school. Results indicate that parents have a strong interest in school garden implementation and activities at their children’s school, with 84% of parents interested in visiting a school garden. Additionally, the majority believe that they can learn from their children (65%) and actively discuss with their children what they are learning at school (72%), indicating a potentially significant likelihood of knowledge transfer from a school garden. Yet, parents’ involvement in their children’s schools and lives varies between regions, with the rurality of the households influencing family social ties and homes’ proximity to the school.
Enfermagem em centro cirúrgico: alerta para a formação do enfermeiro no Brasil
Authors: Caregnato Rita Catalina Aquino , Posso Maria Belén Salazar
Published: April 2023

Editorial
Chaucer's Comic Providence
Authors: Thormann Janet , Fradenburg Joy Aranye
Published: April 2023

Chaucer’s Comic Providence presents readings of five of Chaucer’s Canterbury Tales that dramatize sexual division and the lack of rapport between the sexes. These readings are founded on the psychoanalytic thinking of Jacques Lacan in his rereading of Freud and are motivated by Thormann’s conviction that Chaucer understood what psychoanalysis would come to study as an unconscious operating in the subject that is independent of conscious control and desire. For psychoanalysis, the subject is interminably engaged with unconscious sexual difference and with what Lacan saw as the absence of sexual rapport. Chaucer’s Comic Providence analyzes Chaucer’s plots of sexual adventures, mishaps, and surprise to show how the five tales dramatize the lack of symmetry and absence of accord between the sexes.

Ultimately, Thormann’s interest here is in the ways these five narratives represent and deal with sexual division, in their means of handling what, in any case, cannot be avoided or mastered. Consequently, the resolutions of the narratives sponsor an ethics of desire: they affirm sexual pleasure and acknowledge misprision and limitation, but they do not compromise, close down, or finish with incompatibility, contraction, and limitation. Her reading, then, claims that Chaucer’s poetry already reveals the unconscious that Freud is credited with discovering. As well, Chaucer not only anticipates Lacan’s pronouncement that “the unconscious is structured like a language,” but also his emphasis on unconscious sexual difference and the absence of rapport between the sexes.

With few exceptions, while there has been much consideration of gender in Chaucer’s stories, contemporary criticism of Chaucer has remained inimical or, at the least, largely indifferent, to psychoanalysis, yet because it considers both difference and continuity, change and perpetuation, and because it incorporates psychic processes, motives, functions, and dynamics operating outside of conscious awareness, psychoanalysis offers a wider range for analysis of Chaucer’s tales than does gender theory alone. Chaucer’s Comic Providence also addresses the unexpected, surprising, and providentially comic resolutions of Chaucer’s tales, the concomitant abeyance of sexual conflicts, and the links between emergence and abeyance, which issue in the hope of a beneficent future.
CULTURAL LIFE OF STUDENTS DURING THE PANDEMIC
Authors: Сигида Д.А. , Колесник А.В.
Published: April 2023

В представленной работе проведен анализ культурной жизни студентов в период пандемии. Дано определение студенчеству в современном понимании. Исследованы ключевые тенденции в данном направлении. Охарактеризованы стимулы объединения в культурном направлении. С помощью социального опроса сделан вывод, какие сферы жизнедеятельности изменились, как пандемия оказала влияние на досуг и творчество студентов. В статье описывается, как культура включает в себя совокупность привычек людей и освоенных социальных ролей в повседневной жизни. Другим ее ключевым фрагментом остается общность интересов граждан. Любое предприятие имеет свою корпоративную культуру, так как члены коллектива тоже преследуют одинаковую цель и придерживаются определенной модели поведения, установленной трудовыми нормами. Культура как многогранное понятие, в которое входят установки, ценности и знания, материальные объекты, разделяется членами групп. Это динамично развивающаяся система, меняющаяся вместе с самим обществом, показана связь культуры и молодежи, особенно в условиях, где такого опыта прежде не случалось.

In the presented work, an analysis of the cultural life of students during the pandemic is carried out. The definition of students in the modern sense is given. The key trends in this direction have been studied. The incentives for association in the cultural direction are characterized. With the help of a social survey, it is concluded which areas of life have changed, how the pandemic has affected the leisure and creativity of students. The article describes how culture includes the totality of people's habits and learned social roles in everyday life. Its other key fragment is the community of interests of citizens. Any enterprise has its own corporate culture, as the members of the team also pursue the same goal and adhere to a certain model of behavior established by labor standards. Culture as a multifaceted concept, which includes attitudes, values ​​and knowledge, material objects, is shared by group members. This is a dynamically developing system, changing along with the society itself. The connection between culture and youth is shown, especially in conditions where such an experience has not happened before.
STEM TAPERING OF Eucalyptus spp. USING DIFFERENT CONFIGURATIONS OF ARTIFICIAL NEURAL NETWORKS
Authors: Souza Jianne Rafaela Mazzini de , Castro Renato Vinícius De Oliveira , Tavares Júnior Ivaldo Da Silva , Marcelino Reginaldo Arthur Gloria , Silva Rakiely Martins da , Moretti Sherellyn Daphnee Alves
Published: April 2023

The objective of this work was to test and evaluate different configurations of artificial neural networks (ANNs) for modeling tree stem taper in Eucalyptus spp. in strands in the microregion of Pirapora, Minas Gerais. The data used came from 8,410 Eucalyptus spp. at different speeds. The quantitative variables measured were: age, total height, diameter at the height of 1.30 m (dbh), diameter and height in different positions on the stem. The only qualitative variable measured was the clone. Four scenarios were evaluated: scenario 1 with Ht, dbh, hi, A and Clone inputs; scenario 2 with Ht, dbh, hi and Clone; scenario 3 with Ht, dbh, hi and A; and scenario 4 with Ht, dbh and hi. We tested different ANNs topologies of the Multilayer Perceptron type. The ANNs 102 (neurons in the hidden layer = 18; function = Exponential; algorithm = Rprop), 91 (neurons in the hidden layer = 19; function = Exponential; algorithm = Rprop), 13 (neurons in the hidden layer = 7; Function = Exponential; Algorithm = SCG) and 27 (neurons in the hidden layer = 6; function = Exponential; algorithm = Rprop) presented the best measures of statistical accuracy in training to predict the bottleneck in scenarios 1, 2, 3 and 4, respectively. The ANN 103 (neurons in the hidden layer = 19; function = Exponential; algorithm = Rprop) from scenario 1 presented good statistical results in the validation. Thus, the ANNs were efficient in predicting the diameter along the Eucalyptus spp stem.
ANALYSIS OF THE HORIZONTAL STRUCTURE OF THE YOUNG REGENERANT BANK IN A DEGRADED RIVERSIDE ECOSYSTEM IN THE SEMIARID OF PARAIBA
Authors: Silva Geneilson Evangelista da , Barbosa Francisca Maria , De Lacerda Alecksandra Vieira
Published: April 2023

The objective was to evaluate the structure of the young regenerating stratum in a degraded riverside area of caatinga in the Serra Branca-PB, the semiarid region of Paraíba. Two inventories were performed, one in the dry season (September/2019) and the other in the rainy season (March/2020). In the riparian area, 50 contiguous plots of 10 X 20 m were allocated. In the center of each plot, subplots of 1 X 1 m were plotted, totaling 50 m2, for the evaluation of the regenerating stratum. The density, frequency, dominance, and importance value parameters were calculated. The heterogeneity of the floristic community was determined by the Shannon diversity index (H') and Pielou's evenness index (J'). In both inventories, 39 species distributed in 31 genera and 14 families were recorded. In the dry period, the species with the highest importance value were respectively Alternanthera tenella Colla, Sida galheirensis Ulbr. and Fabaceae 1. Related to the rainy season, the species with the highest importance value were Urochloa decumbens (Stapf), R.D.Webster, Blainvillea acmella (L.), Philipson, and Boerhavia diffusa L. The diversity and evenness values were 1.22 nats.ind.-1 and 0.49 (dry season) and 2.59 nats.ind.-1 and 0.71 (rainy season), respectively. The results obtained in the two inventories were similar to other studies in these same conditions of degraded caatinga. The study also demonstrated that this area is in an initial stage of ecological succession, with a predominance of exotic species in both inventories (dry and rainy).
DETERMINATION OF E. benthamii PROPERTIES BY INFRARED SPECTROSCOPY AND PLS
Authors: Benin Cristiane Carla , Watzlawick Luciano Farinha , De Lima Vanderlei Aparecido
Published: April 2023

Considering the interest in the Eucalyptus benthamii species and the search for alternatives to determine some physical properties in a fast and reliable way, the objective of this study was to build multivariate calibration models through the near infrared spectroscopy (NIR) technique and partial least squares regression (PLS) for wood basic density (BD) and chip moisture (U). Trees were sampled in five diametric classes and used to evaluate DB, as a function of 3 ages and 3 production regions of E. benthamii. We considered only plantations at 7 years of age in the harvest phase and chip samples considering pre-defined intervals of ten days, from the date of tree harvest to 90 days, in two seasons of the year (winter and spring) for moisture analysis. For DB and U, NIR models were calibrated and validated using partial least squares (PLS) regression. Calibration models were evaluated by correlation coefficients (R²), root mean square error (RMSE), and variance performance ratio (RPD). The models for near infrared (NIR) spectroscopy showed R² values ranging from 0.60 to 0.68 for basic density and 0.72 for moisture. The best model for DB observed was the one that considered only the DAP samples. It was concluded that the NIR technique was suitable for estimating the properties of moisture and wood density in this evaluated species, E. benthamii.
Lo “statuto” del pubblico ministero europeo italiano
Authors: Bontempelli Manfredi
Published: April 2023

I poteri e lo statuto dei pubblici ministeri italiani che operano nella Procura europea devono essere definiti non solo alla luce della disciplina sovranazionale di riferimento, ma anche dei principi costituzionali sul pubblico ministero. La limitazione dell’indipendenza funzionale interna del procuratore europeo delegato è compatibile con le norme della Costituzione, con criticità residue riguardanti il meccanismo di supervisione da parte dei procuratori europei. Va, invece, analizzata criticamente la tesi della dottrina che esclude l’applicazione della regola della « piena autonomia » del magistrato in udienza.
Fusion System for Blockchain Asset Securitization Risk Control Using Adaptive Deep Learning-Based Framework
Authors:   Department of medical instrument engineering techniques, Alfarahidi University, Baghdad, Iraq, .. Raed ,   Al-Turath University College, Baghdad, 10021, Iraq,   Computer Communication Department, Al Rafidain University College, Baghdad, Iraq,   Department of computer engineering techniques, Mazaya University College, Thi Qar, Iraq,   Department of Intelligent Medical Systems, Al- Mustaqbal University college, Babylon 51001, Iraq, Ahmed Omar Saad , Al-Sharify Talib A. Al , Hameed Wasfi , Marjan Riyam K.
Published: April 2023

Feature engineering methods, which entail identifying and extracting useful features from big datasets, can be used to enhance the precision of asset securitization. It might be difficult to securitize assets that produce multiple receivables, such as consumer or company debt. In order to overcome these difficulties, companies might think about adopting a fusion system that integrates feature engineering with distributed ledger technologies such as blockchain. Businesses can benefit from implementing a fusion system like the Deep learning-based Adaptive Online Intelligent Framework (DLAOIF) since it allows for better decision-making, less wasted time and money, and less chance of fraud. Financial asset tracking on a blockchain can help investors keep a closer eye on asset performance and related risks, while also decreasing their reliance on credit rating agencies. Blockchain's high data security standards and elimination of regulatory bottlenecks in the securitization process also make it a useful tool for easing the burden of due diligence.
Changement, tendance et variabilité climatique en Haïti durant les 1000 dernières années à partir des processus organo-minéraux du lac Azuei
Authors:   ,   Université Quisqueya, Nocent David
Published: April 2023

Few studies on the reconstruction of climate change in Haiti have indicated that there have been changes in precipitation patterns over the past millennium. However, climatic mechanisms have not been proposed to elucidate them. This thesis aims to study the environmental and climate variability in Haiti during the last 1000 years in order to make significant progress in understanding these variabilities at different time scales and the associated ocean-atmosphere mechanisms. To achieve this objective, the work is based on a multi-proxy and multi-period approach with sedimentological, geochemical and mineralogical analyzes of a well-dated sediment core taken from Lake Azuei (Haiti). The temporal variations of the different proxy analyzed are grouped into four periods: the Medieval Climate Anomaly (MCA, 1000-1100 CE; subdivided into MCA1 (1000-1050 CE) and MCA2 (1050-1100 CE)), the transition period between the Medieval Climate Anomaly and the Little Ice Age (MCA-LIA, 1100-1400 CE), the Little Ice Age (LIA, 1400-1800 CE), and the Modern Warm Period (CWP, 1800 to our days). The MCA1 and LIA periods are marked by a decrease in the sedimentation rate and a decrease in detrital inputs linked to a decrease in precipitation. There was more denitrification related to suboxic conditions as a result of an increase in lake water temperature that is related to dry conditions. On the other hand, during MCA2 there was an increase in the sedimentation rate and an increase in detrital inputs into the lake which are due to an increase in precipitation and therefore an environment characterized by humid conditions. There was also a decrease in denitrification related to more organic matter input. The MCA-LIA transition period was characterized by unstable environmental and climatic conditions, with alternating wet and dry conditions. During PCM there is a gradual increase in the sedimentation rate due to the input of sediment into the lake during rainy periods as a result of erosion in the watershed as a result of anthropogenic activities. The results showed that Haiti has experienced progressively drier conditions over the past millennium and that rainfall is related to mean changes in ocean temperature, Atlantic and Pacific, through the Atlantic Multidecadal Oscillation (AMO), the El Nino Southern Oscillation (ENSO) and the Pacific Decadal Oscillation (PDO). Temporal correlation of our data with other Caribbean paleoclimate records shows that the trends observed in Lake Azuei were controlled by regional climate, likely associated with changes in the position of the Intertropical Convergence Zone (ITCZ). This research has therefore provided new detailed information on the environmental variations of Lake Azuei and hydro-climatic in Haiti during the last millennium.
THE PECULARITIES OF TUBERCULOSIS, CAUSED BY BEIJING STRAINS
Authors: Chesnokova М. М. , Bazhora Yu. І. , Antonenko K. О. , Ostapchuk K. V.
Published: April 2023

East Asian family Beijing M. tuberculosis is a family characterized by active distribution. The article analyzes the association between the features of the course of newly diagnosed tuberculosis in patients infected with pathogens of the Beijing family in comparison with the non-Beijing group. Cultures of M.tuberculosis for molecular genetic research were obtained from 87 patients with first diagnosed pulmonary tuberculosis. According to the presence of the IS6110 insertion fragment in the dnaA-dnaN region, 26,4% of the isolated cultures were reffered to the Beijing family. The medical records of 87 patients with pulmonary tuberculosis were analyzed. Patients infected with pathogens of the Beijing family more often has disseminated form of tuberculosis then infiltrative (60,9% to 30,5%, RR 2,0 CI 1,0 – 4,03), longer period of positive bacterioscopic and cultural tests for M.tuberculosis (RR 1, 8 CI 1,04 – 3,01), more common treatment failure. Higher frequency of mutations of the katG, inhA, rpoB genes, which cause resistance to isoniazid and rifampicin, and multiresistance was detected more often compared to non-Beijing pathogens. In the group of Beijing strains, the level of multiresistance detected by cultural method 31,6% versus 8.5% in non-Beijing, i.e. strains of the Beijing family were characterized by multiresistance 3.7 times more often according to the cultural study than isolates of the non-Beijing group (р<0.05; χ2=8.22) The obtained results permit to speculate that M. tuberculosis infection of the Beijing family is a risk factor for more severe corse of the disease.

Key words: tuberculosis, effectiveness of treatment, Beijing family, drug resistance, M.tuberculosis.
FEATURES OF DIAGNOSIS AND TREATMENT OF CROHN’S DISEASE (CLINICAL CASE)
Authors: Todurov I. M. , Perekhrestenko O. V. , Prokhorenko O. K. , Kupets V. Ye. , Panasenko O. O. , Plehutsa O. I. , Baka O. M. , Pechyborshch O. V. , Maidaniuk V. P.
Published: April 2023

The exact reason for the occurrence of Crohn’s disease remains unknown. It is believed that pathology can be carried out by infectious and viral pathogens, deviations from the norm of natural balance of the microflora of the gastrointestinal tract (hereinafter – the gastrointestinal tract). Many researchers indicate an abnormal autoimmune response of the body on food stimuli – in favor of such an assertion indicates the systematic impression of the internal organs. However, for the emergence and development of this disease, there are significant impacts with harmful habits, such as: smoking, alcoholic beverages and medicines, unbalanced nutrition and the presence of chronic inflammatory gastroids. The inflammatory process begins in the mucous membrane, gradually affects all layers of the wall of the gastrointestinal wall, leads to its destruction and fibrosis and the formation of fistish and stenoses. Therefore, early diagnosis and timely treatment prevents the development of complications, including such severe such as bleeding, perforation of the intestinal wall, intra-abdominal abscesses, internal and external fists, adhesions of the intestine with the development of obstruction.

Purpose: on the basis of a specific case of HC to investigate and analyze the features of diagnosis and treatment of these patients using an analytical method and a systematic approach.

Materials and methods: The material was a clinical case of HC, methods of instrumental diagnosis and objective analysis.

The results: The concrete case of HC is investigated, features of inspection and diagnostics are defined.

Conclusions: A feature of the diagnosis and treatment of patients with HC is a constant vigilance about the occurrence of complications, the key to the prevention of which is a multidisciplinary approach in the tactics of diagnosis and treatment of these patients.

Key words: Crohn’s disease, features of examination and diagnosis.
METABOLIC PROCESS IN THE ORGANISM IN DIABETIC PATIENTS DURING ORTHOPEDIC TREATMENT
Authors: Rozhko P. D. , Cherednichenko O. V.
Published: April 2023

In patients oral liquid with type 2 diabetes mellitus, who were referred for orthopedic treatment using implants, an increased content of triglycerides, cholesterol and glucose was found. Such state of oral cavity in type 2 diabetes cannot but affect the results of dental implantation. In this regard, patients of the main group were prescribed regular courses of drugs regulating carbohydrate metabolism and microbiocenosis, enhancing immunity and resistance in oral cavity, as well as antioxidant and osteotropic drugs. Biochemical studies of oral liquid showed a fairly high efficiency of proposed complex, which contributes to the normalization of impaired metabolism.
Key words: dental implantation, diabetes mellitus, oral liquid, biochemical parameters.
Association of Low Back Pain with Body Mass Index and Stress Among House Officers in Different Rotational Placements
Authors: Ghaffar Tamjeed , Sultan Sameen , Khalid Amna , Anjum Hadia , Irum Amna , Fawad Muhammad , Rao Awais
Published: April 2023

Low back pain (LBP) is the most common disorder affecting the back's muscles, nerves, and bones and affecting the quality of life. Objective: To find the association of LBP with body mass index and stress among house officers in different rotational placements. Methods: In this cross-sectional study, a sample of 170 participants were recruited. Oswestry disability index was used to assess the LBP and perceived stress scale was used to assess the stress. Inclusion Criteria includes house officers, both male and female and physical therapy internes. Exclusion Criteria includes disability, trauma and congenital disorder. Data were analyzed by IBM SPSS statistics version-25. Results: Out of 170 participants 10(5.9%) were underweight, 60(35.3%) were normal weight, 66(38.8%) were overweight and 34(20%) were obese. p value was .694 which showed that there is no association between LBP and body mass index. The p value for LBP and stress was .458 which showed there is no association. The p-value for LBP and different rotational placement was .000 which shows there is association present. Conclusions: There was no association found between LBP and body mass index, LBP and stress. There is association found between LBP and different rotational placements.
Perforated Stress Ulcer of the Duodenum: a Case of an Unexpected Diagnosis in a COVID-19 Patient Following Dilatation and Curettage Procedure
Authors: Obeidat Naser , Heilat Ghaith , Ajam Tarek , Zoubi Hamzeh
Published: April 2023

Background: Stress ulcers in the upper gastrointestinal tract can arise from pathologies related to erosive or inflammatory insults in critically ill patients. The relationship between stressful bodily events and the ischemia and perforation of stress ulcers is poorly understood. Objective: We present a case of perforated stress ulcer following an abortion that was treated by dilatation and curettage (D and C) and complicated by a coronavirus disease 2019 (COVID-19) infection. Case presentation: A 40-year-old lady presented to the emergency room complaining of diffuse abdominal pain, she was recently diagnosed with an incomplete abortion and managed via a D and C procedure in an external hospital. A computed tomography (CT) scan was done at our center for the abdomen and pelvis, showing extensive pneumoperitoneum, which brought the radiologist’s attention to suspect a small bowel perforation presumably accompanying a uterine perforation secondary to the D and C. There were no obvious signs of pelvic small bowel perforation in the initial CT images. The perforated duodenal stress ulcer was diagnosed the next day by a new CT scan following oral contrast ingestion and managed surgically by repair and omental patch, and no other bowel perforations were found upon surgical exploration. After the surgery, the patient was diagnosed with COVID-19, and her clinical status deteriorated gradually during the following week, and she passed away from a cardiac arrest. Conclusion: It is unclear whether septic abortion or COVID-19 has resulted in stress ulcer perforation in our patient. This case report highlights the importance of raising early suspicion in the diagnosis of stress ulcer perforation in critically ill patients to reduce the risk of morbidity and mortality.
Does Increasing Body Weight Negatively Impact Children’s Muscular Flexibility in Saudi Arabia?
Authors: Alonazi Asma , Shaikh Minaz , Alshammari Falah , Ahmad Fuzail , Alanazi Ahmad , Alyahya Danah
Published: April 2023

Background and Aims:
The incidence of overweight and obesity among children and adolescents is rising. The rise in weight and obesity impairs Saudi children’s physical activity and muscular flexibility, especially during the pandemic. However, few studies focus on the relationship between weight and physical fitness in Saudi. Therefore, this study aims to perform among Saudi Arabian children to assess the relationship between muscular flexibility and weight.
Methods:
A cross-sectional study of 195 children aged 6 to 13 was performed in Saudi Arabia. Children who had not previously experienced musculoskeletal pain, neurological disorders, or congenital or acquired spinal deformities were included. For this study, weight and height measurements were taken to calculate body mass index (BMI) in kg/m2, and a sit-and-reach (STR) test was measured to determine muscular flexibility in centimeters.
Results:
The Pearson correlation between STR and weight was negative (-0.26), with a 95% CI of -0.39 to -0.13, indicating a weak but statistically significant relationship between STR and weight. While controlling for other variables in the model, the regression analysis revealed that for every unit (kg/m2) increase in BMI, muscular flexibility decreased by 0.147 units on average (Beta =-0.147; [95 percent CI: -2.07- (-0.039)]. Gender and muscular flexibility were found to have a negative relationship (Beta =-0.078; [95 percent CI: (-2.98) to (0.86)].
Conclusions:
Being overweight and obese were inversely related to muscular flexibility as measured by STR, with no meaningful distinctions between boys and girls.
Does the Saudi Population Have Awareness and Perception Regarding New Treatment Options Other than Medications For Migraine?
Authors: AlHadlaq AbdulMajeed , Alamri Omar , Lazher Jalwi , Obeid Faisal
Published: April 2023

Background and Aims:
Migraine is the sixth most frequent disease globally and is the second leading cause of years lived with disabilities globally disease worldwide. The options for treatment were limited, until recently. The options and methods are increasing in numbers and ways. The goal of this research is to assess the awareness and perception of the Saudi population toward treatment options for migraine other than prescribed medications.
Methods:
The study is an analytical cross-sectional. We targeted the Saudi population. The data was collected starting from Jan till the end of Feb 2022. The survey was optional and distributed online. A total of 1380 responses were collected. We used R studio (v.4.1.2) to summarize, visualize, and statistically analyze the data. The p-value of Fisher’s exact test and Pearson’s chi-squared test were used to assess the statistical differences for qualitative data.
Results:
More than one-half (54.3%) of the participants used pain killers for migraine treatment; however, those who used specific drugs such as Sumatriptan, Eletriptan, or Ergotamine accounted for only 41.9%. Most respondents (n = 702, 55%) chose “avoiding noise and bright light” as non-pharmacological measure to relieve migraine. On the other hand, only 93 (7.3%) participants from the sample group knew that surgery is an available option for treating migraine, making it the least chosen option. Almost a third of respondents (31.8%) accepted when they were asked whether they would accept other interventional treatments if diagnosed with migraine. Females were more willing to accept these options (36%), whereas only 23% of males agreed. The awareness of the respondents, the diagnosed respondents, and the non-diagnosed were (n=515, 40%), (n=112, 60%), and (n=403, 37%) respectively. The comparison was statistically significant with P-value <0.001.
Conclusions:
Awareness of the Saudi population about migraine treatment other than medications is generally low. Physicians treating patients with migraine are advised to educate them about the disease and the treatment options to raise awareness. Also, empowering social media with trusted information plays a major role in raising awareness and spreading knowledge as it appeared to be an important source for diagnosed and non-diagnosed in this study results.
Prevalence of Mycoses and Investigation of Fungal Indoor Environment
Authors: Khateb Aiah , Mohammed Fadwa , Alsubhi Fai , Abdullah Razan , Alkatib Saniyya
Published: April 2023

Background and Aims:
The incidence of fungal infections in Saudi Arabia is increasing with an increase in the population of high-risk patients. Still, studies highlighting the impact of environmental fungal agents on infections in Saudi are limited, and none have examined the Medina region despite the city’s stature, diversity, and travel flow. This study aims to determine the fungal distribution across the Medina region.
Methods:
A randomized 212 indoor samples were collected based on analyzed data from 1374 questionnaires. The prevalence of participants to fungal infection was 19.2% and 26.3% in the risk group. Fungal species were identified via macroscopic and microscopic examination.
Results:
Two hundred and three (96%) samples showed fungal growth. Yeast identified were 78 (34%) Candida species, 56 (25%) non-Candida species. The study identified 13 genera and 20 species for mould, including 38 (17%) Aspergillus spp., 20 (9%) Rhizopus spp. 9(4%) holoarthic/enteroatric conidiogenesis, 7 (3%) Mucor spp. 4 (2%) of both Penicillium spp. and Neurspora spp. and only 2(1%) of Madurella spp., 3(1%) Epidermophyton spp., 2 (1%) Lichtheimia spp., and 1(1%) Peacilomyces spp.
Conclusions:
This study identified Aspergillus spp. as the most frequent fungi across the Medina region. The characterization of indoor fungal environment enables healthcare practitioners to anticipate fungal infection for individuals at risk. These findings can aid the prediction and prevention of fungal infections and fungal sensitization among the high-risk populations.
AVALIAÇÃO NA EDUCAÇÃO INFANTIL: ANÁLISE DA LEGISLAÇÃO EDUCACIONAL BRASILEIRA (1996 A 2018)
Authors: Raulino e Silva Rayner , Rodrigues Mirian Barbosa , Ferreira da Silva Anna Lívia
Published: April 2023

Compreendemos que a Educação Infantil etapa da Educação Básica brasileira é uma conquista dos movimentos sociais e como tal advém de um processo sócio-histórico. Entretanto, é uma conquista recente e está em intensas mudanças, entre essas mudanças, está na significação do processo avaliativo. Por isso, esse artigo tem como objetivo analisar como os documentos legais abordam sobre a avaliação na Educação Infantil. Tendo como fio metodológico a pesquisa documental por analisar seis documentos normativos que são datados de 1996 a 2018 que influenciaram mudanças no contexto educacional brasileiro. Esses documentos que fazem parte desse estudo refletem um olhar que demarca uma noção de sociedade, indivíduo e educação. Nesse processo analítico concluímos que a escola e seus professores compreendam a avaliação como um processo contínuo que deve levar em conta o desenvolvimento da criança diretamente ligado à própria prática pedagógica bem como o seu próprio desenvolvimento levando em comparação a criança nela mesmo.
A FAMÍLIA E O ACOMPANHAMENTO DAS ATIVIDADES ESCOLARES REMOTAS DURANTE A PANDEMIA DO COVID 19 NA EDUCAÇÃO INFANTIL: UMA ANÁLISE DAS PRÁTICAS NO MUNICÍPIO DE COLATINA
Authors: Drago Geisa , Pereira Andrade Nascimento Monica
Published: April 2023

A presente pesquisa objetivou identificar o funcionamento das escolas de Educação Infantil durante o período da pandemia por COVID-19, utilizando-se da metodologia exploratória, baseando-se na leitura de materiais produzidos pela Secretaria Municipal de Educação para a orientação metodológica às escolas para o atendimento educacional à etapa da Educação Infantil, assim como a análise de documentos e formulários disponibilizados pela Equipe de Formação da Secretaria Municipal de Educação de Colatina e pelo Sistema Operacional adotado pela Secretaria Municipal de Colatina para a compilação de dados da rede e produção de documentos. A análise dos documentos citados pautou-se na observação dos planejamentos e atitudes foram tomadas para um bom funcionamento escolar. A pesquisa realizada apontou que os documentos orientadores analisados foram imprescindíveis na condução das ações pedagógicas necessárias para a manutenção da oferta da educação escolarizada para a etapa analisada.
A kettős állampolgárság jogi szabályozása Szlovákiában
Authors: Kartai Gergő
Published: April 2023

Minden szuverén állam a belső jogában önállóan határozhatja meg az állampolgári jogokat és kötelezettségeket, éppen ezért nincs egységes álláspont arra nézve, hogy jogi értelembe mely jogok és kötelezettségek alkotják az állampolgárságot. Ugyan vannak nemzetközi és európai ügyek (lsd. Nottebohm-ügy, Rottmann-ügy, Tjebbes-ügy, Micheletti-ügy), melyek bár kiemelnek bizonyos elvi tételeket, mely tételeket és joggyakorlatot az államoknak figyelembe kellene venniük, azonban ez a jogkövető magatartás nem mindig érvényesül. Az1960-as évek végétől Csehszlovákiában több törvény is rendelkezett a szlovák, a cseh és a szövetségi állam állampolgárságának megszerzéséről és elvesztéséről. A magyar kedvezményes honosítás ellenreakciójaként értelmezhető a szlovák kormánynak a szlovák állampolgárságról szóló törvény alkotmányt sértő, szigorú jellegű módosítása, amely ahhoz vezetett, hogy 2022. decemberéig több mint 4300 ember veszítette el szlovák állampolgárságát. A szlovák Parlament tavaly fogadta el az állampolgársági törvény ismételt módosítását, mely a megfosztott szlovákiai magyarok többségének helyzetén mit sem javított. Felmerül tehát a kérdés, hogy az Európai Unióhoz csatlakozott Szlovákia állampolgársági törvény módosításai megfelelnek-e az európai uniós és a nemzetközi jogi normáknak? Vagy hogy megvalósul-e Szlovákiában az egyenlő elbánás elve az állampolgárság vonatkozásában? Meglátásom szerint ezek mind-mind olyan érdekfeszítő és releváns kérdések, amelyek nagymértékben meghatározzák és rányomják bélyegét a mai társadalmunkra.
Personalization is in the details
Authors: Szabó Lilla Petronella
Published: April 2023

The process of political personalization (namely, politicians taking the center stage rather than political collectives) has been observed from many perspectives by scholars of political communication. A wide range of research measured whether politics was becoming personalized; however, these studies were largely data-driven. In this paper, I argue that in order to gain a fuller understanding of personalized politics, more nuanced analyses need to be conducted, as the detailed interpretation of political communication reveals aspects of political personalization which data-based approaches may overlook. The relevance of qualitative analysis in terms of the personalization of politics is interpreted through the use of first-person singular and plural pronouns in Ronald Reagan’s 1984 and Barack Obama’s 2008 presidential nomination acceptance speeches. The results show that despite a similar level of personalization in quantitative terms in the two speeches, a closer analysis of the texts reveals differences in terms of the semantic categories represented by first-person pronouns.
Модернізація ринку праці на засадах концепту соціальної відповідальності як базова умова відновлення України
Authors: Маршавін Ю. М. , Кицак Т. Г. , Василенко А. О.
Published: April 2023

Актуальність дослідження характеризується необхідністю формування наукового підґрунтя для удосконалення державної політики зайнятості, яка має бути спрямована на модернізацію національного ринку праці, як головного фактора подолання руйнівних наслідків російської воєнної агресії та економічного відновлення України. Метою статті є оцінка процесів і тенденцій, які відбувалися у сфері зайнятості за два передвоєнних десятиліття, обґрунтуванні їх причин і факторів та визначення напрямів й інструментів покращення  функціонування ринку праці та економічного відновлення України на засадах соціально-відповідальних практик. Результатом дослідження стало обґрунтування основних напрямів модернізації національного ринку праці, головними з яких є залучення інвестицій в економіку України для створення нових робочих місць на базі техніко-технологічних елементів Індустрії 4.0. Визначено, що ринок праці України характеризується посиленням негативних процесів, які розвиваються у площині збільшення масштабів зовнішньої трудової міграції, підвищення рівня безробіття та зменшення зайнятості робочої сили, зниження економічної активності працездатного населення. Розглянуто проблему розвитку людського капіталу, зокрема через поліпшення сфери освіти, розвитку виробничої демократії, сповідування стандартів соціальної справедливості та відповідальності. Визначено напрями посилення конкурентних переваг ринку праці України, які передбачають модернізацію державної політики зайнятості відповідно до сучасних прогресивних міжнародних практик; активізацію в Україні політики залучення капітальних інвестицій; розвиток державного регулювання ринку праці у напрямі створення інноваційних робочих місць. Обґрунтовано пропозиції щодо можливості імплементації ідей і положень дослідження у зміст державних програм та планів відновлення України на засадах посилення соціально відповідальних практик, подолання соціально-економічних наслідків російської агресії. Акцентовано увагу на тому, що руйнівні процеси в економіці, загострення кризових явищ в соціальній сфері з врахуванням бойових дій, які вимушена вести наша Україна у відповідь на російську агресію, диктують необхідність наукового обґрунтування шляхів і засобів забезпечення відродження всіх галузей і сфер національного господарства як базису подальшого збалансованого соціально-економічного розвитку.
ХАЛКАРО ВА МИЛЛИЙ ХУКУК ТИЗИМИДА МЕДИАЦИЯ ИНСТИТУТИНИНГ РИВОЖЛАНИШ ТЕНДЕНЦИЯЛАРИ
Authors: Севара Б.
Published: April 2023

Мақолада медиация институтининг тарихий шакллари хамда ривожланиш тенденциялари хорижий давлатлар мисолида таҳлил килинган. Медиациянинг мамлакатимиз ҳуқуқ тизимида тутган ўрни атрофлича ўрганилган. Таҳлиллар асосида бугунги кунда медиация низоларни ҳуқуқий жихатдан тартибга солишнинг янги ижтимоий институти сифатида мухим ахамиятга эга экани тÿғрисида хулоса чикарилган.

The article analyzes the historical forms and development trends of the mediation institute on the example of foreign countries. The role of mediation in the legal system of our country has been thoroughly studied. Based on the analysis, it was concluded that today mediation is important as a new social institution of legal regulation for settlement disputes.

В статье анализируются исторические формы и тенденции развития института медиации на примере зарубежных стран. Автором была тщательно изучена и проанализирована роль медиации в правовой системе нашей страны. На основе проведенного анализа был сделан вывод о том, что сегодня медиация важна как новый социальный институт правового регулирования споров.
РЕФЕРЕНДУМНИНГ ЖАМИЯТ ҲАЁТИДА ТУТГАН ЎРНИ ВА АҲАМИЯТИ
Authors: Зафар Ф.
Published: April 2023

Мақолада референдумнинг жамият ҳаётида тутган ўрни ва аҳамияти, шунингдек, “Ўзбекистон Республикасининг референдуми тўғрисида”ги қонунга киритилган ўзгартириш ва қўшимчалар ҳамда уларнинг юртимиздаги ислоҳотлар самарадорлигини ошириш ва мамлакатимизнинг халқаро майдондаги мавқейини янада мустаҳкамлашдаги ўзига хос жиҳатлари ёритилган.

This article describes the role and importance of the referendum in the life of society, the changes and additions to the Law “On the Referendum of the Republic of Uzbekistan”, the specific aspects of these changes in improving the effectiveness of the reforms implemented in our country and further strengthening the position of our country in the international arena.

В данной статье показаны роль и значение референдума в жизни общества, изменения и дополнения в Закон «О референдуме Республики Узбекистан», конкретные аспекты этих изменений в повышении эффективности проводимых реформ и дальнейшего укрепления позиций нашей страны на международной арене.
МАМЛАКАТИМИЗ МИЛЛИЙ КОНУНЧИЛИГИДА ФУКАРОЛИК ЖАМИЯТИ ИНСТИТУТЛАРИ МАСАЛАСИ
Authors: Жаҳонгир Ш.
Published: April 2023

Мақолада қонунчиликда фуқаролик жамияти институтлари тушунчасидан фойдаланилиши ҳолати, нодавлат нотижорат ташкилотларини "ноҳукумат ташкилотлар" деб номламасликнинг сабаблари, Ўзбекистон Республикасининг Конституциясида фуқа­ролик жамияти институтлари таркибининг очиб берилиши, жамоат бирлашмаларига берилган таърифнинг назарий ва хуқуқий жихатдан бахсли жихатлари чуқур таҳлил этилган ҳамда муаллиф томонидан мавзуга оид таклифлар берилган.

The article provides an in-depth analysis of the use of the concept of civil society institutions in the legislation and the reasons for refusing to name non-governmental non-profit organizations as "non-governmental organizations", disclosing the structure of civil society institutions in the Constitution of the Republic of Uzbekistan, theoretical and legal aspects of defining a public association, and author's suggestions on the subject.

В статье проводится углубленный анализ использования в законодатель­стве понятия институтов гражданского общества, причин отказа от наименования негосу­дарственных некоммерческих организаций в качестве «неправительственных организа­ций», раскрытия структуры институтов гражданского общества в Конституции Республики Узбекистан, теоретических и правовых аспектов определения общественного объедине­ния, а также излагаются авторские предложения по теме.