bluuebunny/crossref_metadata_2025 huggingface dataset:
Does microbial resistance profile change in community-based intra-abdominal infections? Evaluation of the culture results of patients with appendicitis
Authors: Tartar Tugay , Sağmak-Tartar Ayşe , Saraç Mehmet , Bakal Ünal , Akbulut Ayhan , Kazez Ahmet
Published: March 2019

Most common origin of intra-abdominal infections in children is appendicitis. Microorganisms responsible for community-based and hospital-acquired intra-abdominal infections vary. The aim of this study was to evaluate microbial culture outcomes and antibiotic susceptibilities of these microorganisms in samples obtained intraoperatively from pediatric patients with appendicitis, and to define the infectious microorganisms responsible for the community-based intra-abdominal infections in our region, and their antibiotic susceptibilities. This study included 231 patients between 0 and 16 years of age, operated on due to appendicitis between 2014 and 2017. Appendicular tissues were sampled intraoperatively. Antibiogram was studied in case of reproduction in tissue culture. Forms included information on the age and gender of the patients, intra-abdominal event, bacterial growth in microbial culture and antibiogram, antibiotic switch during follow-up, duration of the treatment, complications and outcomes were recorded. No microbial growth was observed following inoculation of the samples obtained from appendiceal tissue of 24.7% patients, whereas growth was positive in 75.3%. Gram negative bacteria were isolated in 94.3% of the patients, whereas gram positive bacteria was isolated in 5.7%. Polymicrobial growth was observed in 2.2% of the patients. E. coli in 79.9%, P. aeruginosa in 5.2%, Enterobacter cloacae in 3.4%, Coagulase-negative staphylococci in 3.4%, Klebsiella spp. in 1.7%, Citrobacter spp. in 1.7%, Enterococcus spp. in 1.7%, Comamonas testosteroni in 1.2% of patients produced. ESBL positivity is present in 51 (36.7%) of 139 E. coli strains reproducing in appendiceal tissue culture. ESBL was positivity detected in one of the reproduced 3 Klebsiella spp. strains. In E. coli, ciprofloxacin resistance as 20.86%, ampicillin-sulbactam resistance as 83.45%, and co-trimoxazole resistance as 41% were found. Our study clearly demonstrates that the resistance profile varies in community-based intra-abdominal infections. Empirical treatment protocols should be revised in especially the patients admitted with septic presentation and where the source control is not possible.
UJI KINERJA ALAT PENGOLAH KAHWA DAUN (TEH HERBAL SUMATERA BARAT)
Authors: Eviza Andi , Novita Rilma , Irzal Irzal
Published: March 2019

Kahwa daun adalah teh herbal produk kearifan lokal Sumatera Barat. Kahwa Daun dibuat dari daun kopi segar dan membutuhkan waktu sekitar 2 minggu jika diolah dengan cara pengolahan tradisional. Produk yang dihasilkan dengan cara tradisional masih terbatas dan hanya dapat memenuhi kebutuhan skala rumah tangga. Seiring dengan diperkenalkannya kembali teh herbal ini awal tahun 2000, maka kahwa daun berkembang menjadi salah satu minuman alternatif yang diminati oleh masyarakat. Hal ini mengakibatkan  naiknya kebutuhan terhadap produk kahwa daun dan mutu produk yang dihasilkan. Tantangan ini tidak dapat dijawab oleh produksi secara tradisional. Berdasarkan latar belakang ini maka dirancang alat pengolahan kahwa daun dengan tujuan dapat meningkatkan kapasitas produksi kahwa daun dan mutu produk yang dihasilkan. Pada tahap awal dilakukan uji kinerja alat. Peralatan dirancang dan dibuat terdiri dari silinder berputar yang digerakkan oleh motor listrik 0,25 HP, terbuat dari stainless steel,  dan energi panas untuk pengeringan bersumber dari kompor LPG. Hasil uji coba kinerja alat  dengan 4 perlakuan (6; 8.5; 10.5; dan 12 rpm),  dengan variasi waktu penyangraian diketahui kadar air menyerupai kadar air produk tradisional tercapai setelah  120-135 menit, pada 8.5 rpm dan 10.5 rpm atau setelah 105-120 menit, pada 12 rpm. Jumlah produk akhir tertinggi dihasilkan dari alat yang diputar dengan kecepatan 10.5 rpm dengan berat 3,8 kg kahwa daun dari 10 kg daun segar. Diketahui alat memiliki kapasitas produksi lebih tinggi dan waktu produksi lebih singkat dibandingkan cara tradisional pada 10.5 rpm.
Enhance Features in URDU.KON-TB
Authors: Munir Saima
Published: March 2019

In this paper, we enhance features are the head & dependent relationship and functional tagset is marked by dependency grammar rules in URDU.KON-TB for increase the accuracy. The SSP and SSS tagset are using [1]. In this way, we conduct one experiment with six different feature models using MaltParser. First we check converted ability of URDU.KON-TB in domain of dependency parsing through conversion, so that’s why we need to proposed formula and defined rules.
EFFECT OF BIO-STIMULATORS ON PRODUCTION OF COWPEA SEED FOR FOOD SECURITY AND WEALTH CREATION IN JUJA, KENYA
Authors: Ilukol Judith Oyoo
Published: March 2019

A study was done to evaluate the effect of bio-stimulators on seed production of cowpea crop in Juja, Kenya during short rains season 2014-15. Bio-stimulators are plant and animal derived substances that trigger plant processes when applied to the plants at very low concentrations. They contain amino acids, low molecular weight polypeptides, vitamins, enzymes, hormones, sugars, betaines and antioxidants. Drought causes slow rate of the majority of plant growth and development processes leading to discontinuation of cell growth, stomatal closures, increased abscisic acid and proline, drop in cytokinins levels, reduced protein synthesis and reduced activity of nitrate reductase leading to retarded growth and plant senescence. In reducing the impact of the water stress therefore, cytokinins in bio-stimulators promote growth and slow down plant senescence. Parameters investigated were germination rate, days to flowering and pod formation, number of seeds per pod, length of pods, total number of pods and weight of seeds. Results on the effect of bio-stimulators on cowpea seed production are discussed.
COFFEE SILVERSKIN AND EXPIRED COFFEE POWDER USED AS ORGANIC FERTILIZERS
Authors: Carnier Ruan , Berton Ronaldo Severiano , Coscione Aline Renee , Pires Adriana Marlene Moreno , Corbo Jessica Zuanazzi Fioritti
Published: March 2019

The coffee industry produces a wide range of organic wastes, some in large amounts, and most of them do not have a well-defined final disposal. The agricultural use of these wastes can be based on the recycling of nitrogen, but their chemical characterization and evaluation with soil under controlled conditions are mandatory. The aim of this work was to evaluate the use of coffee silverskin and expired coffee grounds as organic fertilizers. The wastes were chemically characterized according to CONAMA’S resolution No. 375 and passed through Brazil’s Agriculture Ministry regulation for organic fertilizers and soil conditioners. A greenhouse experiment with Rhodic Ferralsol soil and maize was performed to obtain the agronomic efficiency index (AEI) for nitrogen. The treatments were control (without residue), ammonium nitrate as a mineral reference, and both organic wastes, at a dose of 450 mg of Kjeldahl nitrogen per pot, in triplicate. The data obtained in the characterization were favorable to the wastes as nitrogen sources for agriculture. However, the AEIs obtained were low (0.5 and 7.9% for the expired coffee grounds and the coffee silverskin, respectively) compared to that of the mineral reference (92%). Based on these results, the use of coffee silverskin and expired grounds as organic fertilizers is not recommended but can improve soil attributes and serve as a complementary source of nitrogen and potash.
CONTROL OF THE COFFEE ROASTING STAGE USING ARTIFICIAL VISION TECHNIQUES
Authors: Sarria-González Juan Camilo Camilo , Ivorra-Martínez Eugenio , Girón-Hernández Joel
Published: March 2019

Artificial vision techniques were used to evaluate its application in the control of the coffee roasting stage. Coffee samples of Colombia and Castillo varieties were obtained and analyzed by comparing images during the roasting stage. A one-way ANOVA analysis exhibited 94.28% of similarity of the coffee varieties studied; a multivariate analysis showed significant differences (p<0.05) for the time factor and its interaction with the variety factor, no differences were observed (p>0.05) for the coffee varieties. Additionally, a Principal Component, with two components demonstrated 90.77% of the variance by differentiating the samples in the different roasting times. Therefore, the proposed technique could be used in the control of the coffee roasting stage.
SELECTION OF COFFEE PROGENIES WITH LARGE BEANS RESISTANT TO RUST AND CERCOSPORA LEAF SPOT
Authors: Pereira Fernanda Aparecida Castro , Carvalho Samuel Pereira de , Viana Mariana Thereza Rodrigues , Vidal Douglas Alves , Ferreira Guilherme Souza , Silva Joyce Alves Goulart da , Sâmia Michelly Pereira
Published: March 2019

Rust is the main disease of coffee. Recently, cercospora leaf spot has grown in importance, intensifying defoliation and decreasing grain yield. The aim of this study was to use a mixed model approach to select the best progenies of "Big Coffee VL" for resistance to rust and cercospora leaf spot. We used 12 progenies with high bean yields. Based on bean size, leaves and plant size, plants within each progeny were classified as "small" (P), "medium" (M) and "large" (G). The experimental design was completely randomized, with six replicates and one plant per plot. Six measurements were carried out every 15 days for each plant by selecting 20 fully exposed leaves with higher and lower sun exposures. The measurements summarized disease severity using two diagrammatic scales to obtain the area of the leaf under rust or Cercospora leaf spot. A mixed model approach was used to calculate genotypic value (GV) and heritability estimates. The Mulamba and Mock index was used to select the most resistant progenies, in which the sum of rankings was weighted by a heritability value. Five progenies were selected; three progenies were G (G17, G9, and G12), one progeny was M (M5) and another progeny P (P23). Among these, M5 and P23 progenies are the most productive and may have potential use in future studies. The statistical approach used to predict promising genotypes facilitates the selection of genetically superior individuals for maximizing yields.
GROWTH, ANATOMY AND PHYSIOLOGY OF COFFEE PLANTS INTOXICATED BY THE HERBICIDE GLYPHOSATE
Authors: Castanheira Dalyse Toledo , Alecrim Ademilson De Oliveira , Voltolini Giovani Belutti , Rezende Tiago Teruel , Netto Pedro Menicucci , Guimarães Rubens José
Published: March 2019

Weed control is fundamental in coffee cultivation due to their high interference, competing with the crop for water, light and nutrients. Among the control methods used, chemical control is highlighted, due to its high efficiency and low cost. However, due to application failures, herbicide drift phytotoxicity is common. Aiming at the search for selective active ingredients in coffee, the objective of this study was to evaluate the selectivity of the active ingredient Glyphosate in young coffee plants. The experiment was carried out in a greenhouse with ‘Topázio MG1190’ coffee plants (Coffea arabica L.), cultivated in pots with an 11 L-substrate capacity. The statistical design was RBD, with four replications and four doses of the herbicide, making up 16 experimental plots. Each plot consisted of three plants. The treatments were: (i) 0%; (ii) 10%; (iii) 25% and (iv) 50% of the commercial dose of the herbicide Glyphosate. The evaluations were performed at 104 days after application of the treatments. Growth, morphological, physiological and anatomical characteristics were evaluated. The collected data were analyzed using the SISVAR software. The effect of glyphosate drift impairs plant growth. However, after 104 days of intoxication, there is no longer any effect on the physiology and leaf anatomy of coffee trees.
The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner
Authors: Heberle Alexander Martin , Razquin Navas Patricia , Langelaar-Makkinje Miriam , Kasack Katharina , Sadik Ahmed , Faessler Erik , Hahn Udo , Marx-Stoelting Philip , Opitz Christiane A , Sers Christine , Heiland Ines , Schäuble Sascha , Thedieck Kathrin
Published: March 2019

All cells and organisms exhibit stress-coping mechanisms to ensure survival. Cytoplasmic protein-RNA assemblies termed stress granules are increasingly recognized to promote cellular survival under stress. Thus, they might represent tumor vulnerabilities that are currently poorly explored. The translation-inhibitory eIF2α kinases are established as main drivers of stress granule assembly. Using a systems approach, we identify the translation enhancers PI3K and MAPK/p38 as pro-stress-granule-kinases. They act through the metabolic master regulator mammalian target of rapamycin complex 1 (mTORC1) to promote stress granule assembly. When highly active, PI3K is the main driver of stress granules; however, the impact of p38 becomes apparent as PI3K activity declines. PI3K and p38 thus act in a hierarchical manner to drive mTORC1 activity and stress granule assembly. Of note, this signaling hierarchy is also present in human breast cancer tissue. Importantly, only the recognition of the PI3K-p38 hierarchy under stress enabled the discovery of p38’s role in stress granule formation. In summary, we assign a new pro-survival function to the key oncogenic kinases PI3K and p38, as they hierarchically promote stress granule formation.
A vida nua e o vida loka: reflexões a partir do pensamento de Giorgio Agamben.
Authors: Leite Tiago Pereira
Published: March 2019

Giorgio Agamben, filósofo e jurista italiano, nascido em 1942, é um dos autores mais lidos atualmente. Iniciou sua produção acadêmica nos anos 70 tratando de temas relacionados à estética. A partir dos anos 90 volta-se mais objetivamente às questões políticas. A trama conceitual formulada pelo autor é vastíssima, no entanto, para fins desse ensaio, serão abordados os conceitos de estado de exceção, vida nua e campo. Além de discorrer sobre o potencial teórico dessas noções realiza-se uma interface com a categoria nativa vida loka. O objetivo é problematizar em que medida e de que maneira é possível articular a noção de vida nua, proposta por Agamben (2010) à categoria nativa vida loka. Explorando os tencionamentos oriundos dessa articulação, pretende-se verificar a operacionalidade das noções de estado de exceção e campo.
Representações sociais do “jeitinho brasileiro” por trabalhadores de repartições públicas de Brasília
Authors: Maciel Welliton Caixeta , Picelli Isabelle Alline Lopes
Published: March 2019

Objetivou-se, neste trabalho, analisar algumas representações sociais do “jeitinho brasileiro” por quinze trabalhadores/as de repartições públicas de Brasília e, mais especificamente: 1) apreender como percebem e interpretam esse modo característico de lidar com as situações bem como as eventuais ocasiões em que esse “modo de navegar” foi utilizado; 2) em diálogo mais aproximado com a Psicologia Social, verificar a ocorrência do fenômeno da dissonância cognitiva e da autojustificação nas respostas dos/as interlocutores/as. À luz dos conhecimentos sócio-antropológicos, do aporte teórico-metodológico propiciado pela Teoria das Representações Sociais e do material empírico estudado, conclui-se que o “jeitinho brasileiro”, enquanto representação social, se constrói não apenas sobre a capacidade representacional desses sujeitos, como também a partir de engendramentos de representações embebidos de práticas sociais, ou seja, de cultura; não devendo, pois, ser entendido fora de uma dimensão de alteridade.
A Cidade-Memória: a Salvador de A Grande Feira
Authors: Souto Mirela
Published: March 2019

artigo tem por objetivo entender de que forma a cidade de Salvador comparece em A Grande Feira (1961), de Roberto Pires, considerando especialmente nesse filme a sua perspectiva de enquadramento da cidade na qual vivia, bem como, talvez, a sua pretensão de eternizá-la na memória. Nossa discussão é articulada ao tema da paisagem, para entendermos a temática da geografia do cinema e a subjetividade do olhar, a partir da noção de espaço. Utilizamos esse filme não como objeto de análise fílmica, mas sim como fonte ilustrativa da nossa discussão entre cinema, memória e espaço urbano.
Som e Fotografias
Authors: Sobral Filipe
Published: March 2019

Som e Fotografias.
Implementasi Program Keluarga Harapan Di Kecamatan Tamalate Kota Makassar
Authors: Dheby Clara , Adys Abdul Kadir , Idris Muhammad
Published: March 2019

The objective of this research is to know the implementation of expectation family program In Tamalate sub-district of Makassar City. This research is qualitative and the type is phenomenology. The data is obtained by interview, observation, and documentation. The source of data is primary and secondary data. The informant involved in this research is ten informants. A technique of data analysis pervades reduction of data, presentation of data, conclusion, and verification. The legality of data pervades source triangulation, technical triangulation, and time triangulation.The result of this research reveals that Expectation Family Program in health field in Tamalate sub-district has applied digital financial service and health facility providing well. The Expectation Family Program in education field of Tamalate sub-district is not maximal yet, in particular on activation of illiterate children and home providing.Keywords : Implementation of policy, Expectation Family Program Tujuan penelitian ini adalah untuk mengetahui implementasi Program Keluarga Harapan di Kecamatan Tamalate Kota Makassar. Jenis penelitian adalah kualitatif dan tipe penelitian adalah fenomenologi. Data diperoleh melalui wawancara, observasi dan dokumentasi. Sumber data penelitian adalah data primer dan sekunder. Jumlah informan penelitian adalah 10 orang. Teknik analisis data meliputi reduksi data, penyajian data serta penarikan kesimpulan dan verifikasi. Pengabsahan data meliputi triangulasi sumber, triangulasi teknik dan triangulasi waktu. Hasil penelitian menujukkan bahwa PKH bidang kesehatan di Kecamatan Tamalate telah melaksanakan dengan baik layanan keuangan digital dan penyediaan fasilitas kesehatan. PKH bidang pendidikan di Kecamatan Tamalate belum memaksimalkan Pengentasan anak buta huruf dan penyediaan rumah singgah. Kata kunci : Implementasi Kebijakan, Program Keluarga Harapan (PKH)
Inovasi Pelayanan Publik Bidang Kesehatan Berbasis Home Care Di Kota Makassar
Authors: Putra Arjuna , Usman Jaelan , Abdi Abdi
Published: March 2019

This research aims to find out the implementation of Home Care innovation, it some factors that influence home care, and public services are received by society. The type of this research is Qualitative Research byusing 6 informants. The data collection techniques are observation, interview, and documentation. Result of this research presents in implementation of home care has been well with many superiorities. While, there are difficulties although home care innovation has been implemented and it can bee seen by the society in practice. The implementation of home care innovation in Makassar are influenced by the presence of Human Resources, Infrastructures, and frequency of socialization by managing of Home Care. Keywords: Innovation, Public Service, Home Care ABSTRAK Penelitian ini bertujuan untuk mengetahui pelaksanaan inovasi home care, faktor-faktor yang mempengaruhi pelaksanaan home care serta pelayanan publik yang diterima oleh masyarakat. Tipe penelitan yang digunakan adalah penelitian kualitatif dengan informan sebanyak 6 orang.Teknik pengumpulan data yang digunakan adalah observasi, wawancara dan dokumentasi. Hasil penelitian ini menunjukkan bahwa secara pelaksaanan home care telah terlaksana dengan baik dengan berbagai keunggulan yang bervariasi. Adapun tingkat kesulitannya walaupun inovasi home care terlaksana dan dapat dilihat secara nyata oleh masyarakat dalam praktik inovasi tersebut. Pelaksanaan inovasi home care di Kota Makassar dipengaruhi oleh adanya sumber daya manusia, sarana dan prasarana yang memadai, dan sosialisasi yang sudah sering dilakukan oleh pelaksana home care.Kata kunci: Inovasi, Pelayanan Publik, Home Care
RESPONSIVITAS KEPOLISIAN DALAM PENANGGULANGAN GENG MOTOR DI KECAMATAN SOMBA OPU KABUPATEN GOWA
Authors: Alfian Alfian , Muhammadiah Muhammadiah , Said Alimuddin
Published: March 2019

The objective of this research is to find out the Police Responsiveness towards the Prevention ofMotorcycle Gangs at SombaOpuDistric of Gowa Regency. The type of this research is a qualitativeresearch with case study by describing the police responsivenesstowards the prevention ofmotorcycle gangs at SombaOpu District. The data collection technique was conducted through interview, observation and documentation. The data were analyzed through some steps such as data collection, data reduction, data display and conclusion. For the data validation, the researcher applied triangulation method such as: resource triangulation, technique triangulation, and time triangulation. The results of the research reveal that the Police responsivenesstowards the prevention of motorcycle gangs with 3 indicators are: 1) responsive, 2) fast, and 3) on target. The police have strongly responded to the public complaints related to the motorcycle gangs,yetit is not quite fast or precise in solving motorcycle gang cases. Key word: Responsiveness, prevention, motorcycle gangs ABSTRAK Tujuan Penelitian ini adalah untuk mengetahui bagaimana responsivitas Kepolisian dalam penanggulangan geng motor di Kecamatan Somba Opu Kabupaten Gowa. Jenis penelitian adalah kualitatif dengan menggambarkan responsivitas Kepolisian dalam penanggulangan geng motor di Kecamatan Somba Opu Kabupaten Gowa. Tipe penelitian adalah studi kasus. Dalam pengumpulan data digunakan teknik wawancara, observasi dan dokumentasi. Teknik analisis data menggunakan pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Keabsahan data digunakan triangulasi yaitu triangulasi sumber, triangulasi teknik dan triangulasi waktu. Hasil penelitian menunjukan bahwa responsivitas Kepolisian dalam penanggulangan geng motor dengan indikator 1) Tanggap, 2) Cepat, 3) Tepat. Kepolisian sangat merespon keluhan masyarakat terkait masalah geng motor namun belum begitu cepat maupun tepat dalam menyelesaikan kasus geng motor. Kata kunci : responsivitas, penanggulangan, geng motor
Pengaruh Pengawasan Terhadap Efektivitas Kerja Pegawai Kantor Pt Pln (Persero) Wilayah Sulselbar
Authors: Rahman Nurwahda , Rahim Samsir , Elfiansyah Hafidz
Published: March 2019

The aims of this research were to find out to what extent the effectiveness of the supervision, the employees’ working effectiveness, and the influence of supervision on employees’ working effectiveness in the office of PT. PLN (Persero) for South-Southeast-West Sulawesi Regions at Secretariat Section for City of Makassar. The focus of the research used Sondang P. Siagian’s theory (namely, direct and indirect supervision) and Hasibuan’s theory (namely, working quantity, working quality, time management and the quality improvement of human resources). The type of this research was quantitative research. Techniques of data collection in this study were literature reviews and field study consisting of observation and questionnaire. The results indicated that the employees’ working effectiveness in the office of PT. PLN (Persero) for South-Southeast-West Sulawesi Regions at Secretariat Section for City of Makassar had not been effective yet. This happened because there were still many employees who were late to go to the office and not careful in carrying out their work. Based on the results of the determination test (R2), it can be concluded that the influence of the supervision on employees’ working effectiveness is 61.3%.Keywords: Influence, Supervision, Effectiveness Of Employee WorkABSTRAKTujuan penelitian adalah untuk mengetahui seberapa efektif pengawasan, seberapa efektif efektivitas kerja pegawai dan seberapa efektif pengaruh pengawasan terhadap efektivitas kerja pegawai di kantor PT PLN (Persero) Wilayah Sulselrabar Bagian Sekretariat Kota Makassar. Fokus penelitian menggunakan konsep atau teori oleh Sondang P. Siagian yaitu, pengawasan langsung dan pengawasan tidak langsung dan teori Hasibuan yaitu, kuantitas kerja, kualitas kerja, pemanfaatan waktu, dan peningkatan kualitas sumber daya manusia. Jenis penelitian yang digunakan oleh peneliti ialah penelitian Kuantitatif. Teknik pengumpulan data dalam penelitian ini menggunakan penelitian keperpustakaan dan studi ke lapangan yang terdiri dari observasi dan angket/kuesioner. Hasil penelitian menunjukkan bahwa efektivitas kerja pegawai di kantor PT PLN (Persero) Wilayah Sulselbar Bagian Sekretariat Kota Makassar belum efektif. Hal tersebut terjadi karena masih banyak pegawai yang terlambat ke kantor dan masih ada pegawai yang kurang teliti dalam melaksanakan pekerjaannya. Berdasarkan hasil uji determinasi ( ) dapat disimpulkan bahwa pengaruh variabel pengawasan terhadap variabel efektivitas kerja pegawai sebesar 61,3%.Kata Kunci: Pengaruh, Pengawasan, Efektivitas Kerja Pegawai
Clonal expansion of community-associated meticillin-resistant Staphylococcus aureus (MRSA) in people who inject drugs (PWID): prevalence, risk factors and molecular epidemiology, Bristol, United Kingdom, 2012 to 2017
Authors: Packer Simon , Pichon Bruno , Thompson Stephen , Neale Jane , Njoroge Jacquelyn , Kwiatkowska Rachel M , Oliver Isabel , Telfer Maggie , Doumith Michel , Buunaaisie Camillus , Heinsbroek Ellen , Hopewell-Kelly Noreen , Desai Monica , Hope Vivian , Williams Owen Martin , Kearns Angela , Hickman Mathew , Gobin Maya
Published: March 2019

Background: In 2015, Bristol (South West England) experienced a large increase in cases of meticillin-resistant Staphylococcus aureus (MRSA) infection in people who inject drugs (PWID).

Aim: We aimed to characterise and estimate the prevalence of MRSA colonisation among PWID in Bristol and test evidence of a clonal outbreak.

Methods: PWID recruited through an unlinked-anonymous community survey during 2016 completed behavioural questionnaires and were screened for MRSA. Univariable logistic regression examined associations with MRSA colonisation. Whole-genome sequencing used lineage-matched MRSA isolates, comparing PWID (screening and retrospective bacteraemia samples from 2012-2017) with non-PWID (Bristol screening) in Bristol and national reference laboratory database samples.

Results: The MRSA colonisation prevalence was 8.7% (13/149) and was associated with frequently injecting in public places (odds ratio (OR): 5.5; 95% confidence interval (CI):1.34–22.70), recent healthcare contact (OR: 4.3; 95% CI: 1.34–13.80) and injecting in groups of three or more (OR: 15.8; 95% CI: 2.51–99.28). People reporting any one of: injecting in public places, injection site skin and soft tissue infection or hospital contact accounted for 12/13 MRSA positive cases (sensitivity 92.3%; specificity 51.5%). Phylogenetic analysis identified a dominant clade associated with infection and colonisation among PWID in Bristol belonging to ST5-SCCmecIVg.

Conclusions: MRSA colonisation in Bristol PWID is substantially elevated compared with general population estimates and there is evidence of clonal expansion, community-based transmission and increased infection risk related to the colonising strain. Targeted interventions, including community screening and suppression therapy, education and basic infection control are needed to reduce MRSA infections in PWID.
Computer-assisted, high-frequency, hospital-wide point prevalence surveys of hospital-acquired infections in a tertiary care hospital, the Netherlands, 2013 to 2014
Authors: Streefkerk H Roel A , Willemsen Sten P , van der Hoeven Conrad P , Vos Margreet C , Verkooijen Roel PAJ , Verbrugh Henri A
Published: March 2019

Background

Surveillance of hospital-acquired infections (HAI) often relies on point prevalence surveys (PPS) to detect major deviations in the occurrence of HAI, supplemented with incidence measurements when more detailed information is needed. In a 1,320-bed university medical centre in the Netherlands, we evaluated an electronically assisted surveillance system based on frequently performed computer-assisted PPS (CAPPS).

Aim

The primary goals were to evaluate the performance of this method to detect trends and to determine how adjustments in the frequency with which the CAPPS are performed would affect this performance. A secondary goal was to evaluate the performance of the algorithm (nosocomial infection index (Nii)) used.

Methods

We analysed the data of 77 hospital-wide PPS, performed over a 2-year period (2013 and 2014) and including 25,056 patients.

Results

Six trends with statistical significance were detected. The probability to detect such trends rapidly decreased when PPS are performed at a lower frequency. The Nii and its dynamics strongly correlated with the presence of HAI.

Conclusion

Performing computer-assisted, high frequency hospital-wide PPS, is a feasible method that will detect even subtle changes in HAI prevalence over time.
Registro del colibrí barba negra (Archilochus alexandri) en el estado de Querétaro, México
Authors: Patiño-González Blanca Itzel , Pineda-López Rubén
Published: March 2019

Reportamos los primeros registros formales del colibrí barba negra (Archilochus alexandri) para el estado de Querétaro, México. Estos registros corresponden a tres sitios: el Parque Nacional El Cimatario, el Parque Nacional Cerro de las Campanas y un remanente de vegetación (dentro de la ciudad); donde observamos a la especie durante la migración, en 2014 y hasta el 2017. El colibrí barba negra visitó flores de muérdago (Psittacanthus calyculatus), flores de palo bobo (Ipomoea murucoides) y flores de espuela de caballero (Justicia candicans). Esta información confirma la presencia del colibrí barba negra en el estado de Querétaro y apoya su inclusión en el listado de avifauna de Querétaro.
Farklı Rakımlarda Yetiştirilen Bazı Kayısı Çeşitleri ile Zerdali Meyvelerinde Fenolik Bileşiklerin İncelenmesi
Authors: KAN Tuncay , KARAAT Fırat Ege
Published: March 2019

Fitokimyasallar insan sağlığını destekleyen en önemli mikro
besleyicilerinden olup; kanser ve kalp hastalıkları gibi tahrip edici
hastalıklar üzerine, etki mekanizmasının olduğu bilinmektedir. Bu çalışmada,
Malatya’da deniz seviyesinden 1040 m ve 1490 m yükseklikte yetiştirilen
Hacıhaliloğlu, Kabaaşı ve Çataloğlu kayısı çeşitleri ve Zerdali meyve
örneklerinde farklı antioksidan fitokimyasalların miktarları UV- DAD dedektörü
ile yüksek basınçlı sıvı kromotoğrafisi (HPLC) cihazı kullanılarak
belirlenmiştir. Bu kapsamda ilgili meyve örneklerinde gallik asit, p-kumarik asit, ferulik asit, kafeik
asit, klorojenik asit, kateşin, epikateşin, epigallokateşin, rutin,
prosiyanidin B1, prosiyanidin B2, prosiyanidin B3 ve 3-B-Q-D içerikleri
incelenmiştir. İncelenen tüm özelliklerde çeşitler ve zerdali örnekleri
arasında istatistiksel olarak önemli farklılık tespit edilmiştir (P<0.05).
Sonuçlar incelendiğinde, 1490 m rakımdan alınan meyve örneklerdeki fenolik
bileşik miktarlarının daha yüksek olduğu görülmüştür. En yüksek gallik asit ve
klorojenik asit içeriği 1490 m rakımda yetiştirilen Çataloğlu çeşidinde
(sırasıyla 305.25 ve 20916.65 µg/100 g) elde edilirken, en yüksek kateşin ve
epikateşin içerikleri yine 1490 m rakımda yetiştirilen Kabaaşı çeşidinde
(6372.80 ve 788.90 µg/100 g) tespit edilmiştir.
Analisis Tingkat Kesulitan Yang Dialami Peserta Didik Dalam Praktikum Biologi di SMA
Authors: Khaerunnisa Baiq Siti , Kusmiyati Kusmiyati , Ilhamdi Mohammad Liwa
Published: March 2019

Tujuan penelitian adalah untuk mengetahui kesulitan yang dialami peserta didik dalam praktikum pada mata pelajaran biologi kelas XI IPA di SMA Negeri 1 Kopang, Lombok Tengah, provinsi NTB. Jenis penelitian ini adalah penelitian deskriptif. Populasi dalam penelitian ini yaitu seluruh peserta didik SMA Negeri 1 Kopang yang terdiri dari 552 orang siswa. Teknik pengambilan sampel adalah purposive sampling. Instrumen pengumpulan data yang dugunakan adalah instrumen angkettertutup tipe pilihan ganda. Analisis data dihitung menggunakan rumus persentase tingkat kesulitan dan perbandingan persentase tingkat kesulitan. Hasil analisis data menunjukkan bahwa 76,1% mengalami kesulitan dengan kategori sulit. Kesimpulan untuk tingkat kesulitan peserta didik dalam praktikum adalah keterampilan, kesiapan, psikologis emosional kebiasaan sikap, kondisi jasmani minat praktikum, ketelitian konsentrasi, pengetahuan materi praktikum dan motivasi peserta didik.
Perhitungan Ruang Terbuka Hijau Berdasarkan Emisi Karbon Dioksida
Authors: Abdullah Taufik , Boedisantoso Rachmat
Published: March 2019

Kota Surabaya banyak mengalami perkembangan dibidang transportasi dan industri. Perkembangan ini menyebabkan meningkatnya emisi CO2. Penelitian ini bertujuan untuk menentukan kebutuhan ruang terbuka hijau yang dikeluarkan tiap-tiap area khusus di Kota Surabaya. Penelitian dilakukan dengan pendekatan metode perhitungan ruang terbuka hijau berdasarkan total emisi karbon dioksida yang dikeluarkan tiap-tiap area di sektor transportasi dan industri. Hasil penelitian menunjukkan bahwa sebaran emisi total CO2 di Surabaya Utara adalah 30.500,07 ton CO2/bulan dengan luas ruang terbuka hijau kira-kira 6,16 km2. Surabaya Timur sebaran emisi total CO2 adalah 115.653,46 ton CO2/bulan dengan luas ruang terbuka hijau kira-kira 23,24 km2. Untuk Surabaya Pusat, total emisi CO2 adalah 23.256,46 ton CO2/bulan luas ruang terbuka hijau kira-kira 4,75km2. Surabaya Utara memiliki total emisi CO2 adalah 865.709,04 ton CO2/bulan dengan luas ruang terbuka hijau kira-kira 14,54ÃÂ  km2. Sedangkan di Surabaya Barat, total emisi CO2 adalah 89.203,81 tonCO2/bulan dengan luas ruang terbuka hijau kira-kira 17,73 km2. Jadi kebutuhan ruang terbuka hijau di Surabaya Timur lebih besar dibandingkan dengan area lain karena memiliki total emisi CO2 yang tinggi.
PERKEMBANGAN TERKINI TERAPI RHEUMATOID ARTHRITIS (bagian 2)
Authors: Andisari Hendrata Erry
Published: March 2019

Terapi pada RA telah banyak mengalami kemajuan dewasa ini dan sejalan dengan pengetahuan tentang patogenesis RA, tujuan terapi saat ini adalah mengubah perjalanan dan mengontrol aktivitas penyakit RA. Beberapa kelompok obat-obatan telah digunakan dalam terapi RA diantaranya adalah obat antiinflamasi nonsteroid (OAINS), disease modifying antirheumatic drugs (DMARD) baik yang konvensional (cDMARD) maupun agen biologi (bDMARD), golongan glukokortikoid dan obat - obatan anti nyeri. Dalam beberapa tahun terakhir, perkembangan agen biologi yang memiliki target spesifik terhadap mediator-mediator inflamasi seperti interleukin (IL)-1, IL-6 dan Tumor Necrosis Factor (TNF) menunjukkan efek terapi yang poten terhadap RA. Pada artikel ini akan dipaparkan agen biologi terbaru sebagai terapi terkini pada RA.
ПРОБЛЕМИ ТА ПЕРСПЕКТИВИ РОЗВИТКУ ПІДПРИЄМНИЦЬКОГО ПОТЕНЦІАЛУ СУБ’ЄКТІВ МАЛОГО ТА СЕРЕДНЬОГО БІЗНЕСУ
Authors: Савчук Настя Павлівна
Published: March 2019

The paper seeks to explore the structure of the entrepreneurial capacity of small and medium-sized business entities as a set of their inherent characteristics affecting the realized and latent components of the entrepreneurial success – the so called resident drivers (resources, economic activity types, customization level, competitive advantages, focus on creating social values, entrepreneurial process, customer-based approach) which are triggered by the internal (psycho-physiological, socio-demographic, intellectual and creative properties, universal cultural and professional competencies, the ability to innovate, adaptability level, communications, etc.) and external (the institutional environment, the competition (co-operation) relationships development level, social capital, macro- and mesoeconomic indicators dynamics, the dominant technological paradigm) factors affecting the choice of a business activity pattern (forced / voluntary entrepreneurship / intrapreneurship). It is argued that during the phases of crisis and depression within the medium-term economic cycle the importance of internal factors underpinning the entrepreneurial capacity of small and medium-sized business entities increases dramatically, while the periods of revival and recovery demonstrate greater significance of external factors which involve a range of global (the world markets competition), national (nation-wide legal acts, social capital) and local (regional normative legal acts, acts of representative bodies of local self-government, social capital of local community, ethnic or confessional, etc.) factors. Findings report for a correlation analysis method has revealed that the most significant elements in building the entrepreneurial capacity in terms of ensuring positive dynamics of business performance efficiency indicators are customer value creation, macroeconomic environment dynamics, competition level and the quality of entrepreneurial thinking as evidenced by the results of scenario-based forecasting of business activities.
The Case of Mileva Marić: Was Einstein’s First Wife His Secret Collaborator?
Authors: Esterson Allen
Published: March 2019

The article examines the central claims that purport to
demonstrate that Mileva Marić, Einstein's first wife, collaborated with Einstein on his major scientific work during their marriage. The claims are shown to be based on erroneous information, unreliable sources, and the recycling of assertions that have no factual basis.
sejarah komputer
Authors: arif muhammad
Published: March 2019

Sejarah jaringan komputer bermula dari lahirnya konsep jaringan komputer pada tahun 1940-an di Amerika yang digagas oleh sebuah proyek pengembangan komputer MODEL I di laboratorium Bell dan group riset Universitas Harvard yang dipimpin profesor Howard Aiken. Pada mulanya proyek tersebut hanyalah ingin memanfaatkan sebuah perangkat komputer yang harus dipakai bersama. Untuk mengerjakan beberapa proses tanpa banyak membuang waktu kosong dibuatlah proses beruntun (Batch Processing), sehingga beberapa program bisa dijalankan dalam sebuah komputer dengan kaidah antrian
The Influence of Education and Training Toward the Achievement of Employees Performance at PT. ANTAM. Tbk, Nickel Ore Processing Unit Pomalaa, Indonesian
Authors: Ilham
Published: March 2019

Human resource development is essential for any organization that wants to be a dynamic and growth-oriented. Unlike other resources, human resources have the potential ability rather limited. This potential can be used only by creating a climate that can continuously identify, bring to the surface, maintain and use the ability. An HRD number of techniques have been developed in recent years to carry out the above tasks based on certain principles.This study aims to know the extent of the influence of Education and Training toward the Achievement of Employees Performance at PT. ANTAM Tbk, Nickel Ore Processing Unit Pomalaa. The population in this study was all the employees of PT. ANTAM Tbk, Nickel Ore Processing Unit Pomalaa, totaled 1,060 people, sampling is done by using the formula Slovin, so the sample is 91 people. The analysis method used in this study is a simple linear regression analysis.The results of this study showed that the variables of the Education and Training toward the Achievement of Employees Performance at PT. ANTAM Tbk, Nickel Ore Processing Unit Pomalaa. Is positive and significant impact on the Achievement of Employees Performance. The magnitude of the relationship between education and training variables to the variable of achievement of employee performance at PT. ANTAM Tbk, Nickel Ore Processing Unit Pomalaa, in the amount of 85.60% and the other influenced by other factors outside of education and training.
rupi hardiansyah 165100028
Authors: hardiansyah Rupi
Published: March 2019

Audit sistem informasi adalah proses pengumpulan dan penilaian bukti – bukti untuk menentukan apakah sistem komputer dapat mengamankan aset, memelihara integritas data, dapat mendorong pencapaian tujuan organisasi secara efektif dan menggunakan sumberdaya secara efisien Audit sistem informasi sendiri merupakan gabungan dari berbagai macam ilmu, antara lain traditional audit, manajemen sistem informasi, sistem informasi akuntansi, ilmu komputer, dan behavioral science.
PENGARUH LINGKUNGAN KERJA DAN DISIPLIN KERJA TERHADAP KEPUASAN KERJA KARYAWAN PADA KANTOR SAMSAT PAINAN
Authors: Ifriana  , Susanti Febsri
Published: March 2019

Good quality products in the eyes of consumers will encourage consumers to make purchasing decisions against these products. The purpose of this study is to determine the effect of product quality on consumer decisions in buying lubricants meditran SC on CV. Dul Service Padang. This type of research is quantitative. The population of this study were consumers who bought Pertamina lubricant brand Meditran SC on CV. Dul Service Padang consisting of 53 people is taken by simple random sampling. Data were processed by using simple linear regression using questionnaire. The results showed that there is influence of product quality to consumer decision in buying lubricant Meditran SC at CV. Dul Service Padang (p = 0,000) with adjusted value of Rsquare 0.150 means as much as 15% variable of product quality influence buying decision and the rest 85% influenced by other variable outside research variable.
An Upper Limit to Youth Psychotherapy Benefit? A Meta-Analytic Copula Approach to Psychotherapy Outcomes
Authors: Jones Payton J. , Mair Patrick , Kuppens Sofie , Weisz John R.
Published: March 2019

Across 50 years of research, extensive efforts have been made to improve the effectiveness of psychotherapies for children and adolescents. Yet recent evidence shows no significant improvement in youth psychotherapy outcomes. In other words, efforts to improve the general quality of therapy models do not appear to have translated directly into improved outcomes. We used multilevel meta-analytic data from 502 randomized controlled trials to generate a bivariate copula model predicting effect size as therapy quality approaches infinity. Our results suggest that even with a therapy of perfect quality, achieved effect sizes may be modest. If therapy quality and therapy outcome share a correlation of 0.20 (a somewhat optimistic assumption given the evidence we review), a therapy of perfect quality would produce an effect size of Hedge's g = 0.83. We suggest that youth psychotherapy researchers complement their efforts to improve psychotherapy quality by investigating additional strategies for improving outcomes.
Dewi Yopi Meitita 165100006
Authors: Meitita Dewi Yopi
Published: March 2019

Pada era globalisasi perkembangan teknologi berbasis internet berjalan sangat cepat. Hal ini salah satu nya juga terlihat dalam lingkup bisnis. Perusahaan pasar B2C mengubah cara mereka berinteraksi dengan konsumen secara fundamental dengan mengadopsi internet dalam pelayanan nya (Parasuraman dan Zinkhan 2002). Melalui cara tersebut seharusnya pelanggan akan di untungkan karena dapat mengurangi kos pencarian dan memperoleh informasi langsung (Zeinthan, Parasuraman, dan Malbora, 2002). Di sisi lain, terdapat tantangan potensial dalam mempertahan kan pelanggan yang relative sulit dalam penggunaan internet service (Parasuraman dan zinkhan 2002). Melalui teknologi berbasis internet tersebut, e-commerce menyebar hampir seluruh kehidupan. Salah satu nya bukti adalah pergerakan yang cepat dari travel sales melalui website. Hal ini juga berarti bahwa saat ini penggunaan e-commerce tersebut berasumsi dapat melihat, memilih, dan menyebar layan secara online.
Sensitivity analysis for publication bias in meta-analyses
Authors: Mathur Maya B , VanderWeele Tyler
Published: March 2019

We propose sensitivity analyses for publication bias in meta-analyses. We consider a publication process such that "statistically significant" results are more likely to be published than negative or "nonsignificant" results by an unknown ratio, eta. Our proposed methods also accommodate some plausible forms of selection based on a study's standard error. Using inverse-probability weighting and robust estimation that accommodates non-normal population effects, small meta-analyses, and clustering, we develop sensitivity analyses that enable statements such as: "For publication bias to shift the observed point estimate to the null, 'significant' results would need to be at least 30-fold more likely to be published than negative or 'nonsignificant' results." Comparable statements can be made regarding shifting to a chosen non-null value or shifting the confidence interval. To aid interpretation, we describe empirical benchmarks for plausible values of eta across disciplines. We show that a worst-case meta-analytic point estimate for maximal publication bias under the selection model can be obtained simply by conducting a standard meta-analysis of only the negative and "nonsignificant" studies; this method sometimes indicates that no amount of such publication bias could "explain away" the results. We illustrate the proposed methods using real-life meta-analyses and provide an R package, PublicationBias.
PENGARUH LINGKUNGAN KERJA DAN KARAKTERISTIK INDIVIDU TERHADAP KINERJA KARYAWAN DI KANTOR BPS PROVINSI SUMATERA BARAT
Authors: Kindi Icshan Al , Susanti Febsri
Published: March 2019

The purpose of this study was to determine the influence of work environment and individual characteristics on employee performance at the BPS of West Sumatera Province. Independent variables from this study are work environment and individual characteristics. The research method used is quantitative research. In this study the population amounted to 75 people who are all BPS employees of West Sumatera. The results of this study is there is a significant relationship between the Work Environment (X1) and Employee Performance (Y), Improving the work environment will affect employee performance and there is a significant relationship between Individual Characteristics (X2) with Employee Performance (Y) Meaning the better the individual characteristics make the employee's performance will be higher.
Exercício e saúde: recomendações para o treino da força muscular. Documento de apoio.
Authors: Neiva Henrique P
Published: March 2019

Documento pedagógico 1º ciclo
Confidence intervals in health and medical journals show an implausible excess of statistically significant results
Authors: Barnett Adrian , wren Jonathan
Published: March 2019

Results that are statistically significant are more likely to be reported by authors and more likely to be accepted by journals. These common biases warp the published evidence and undermine the ability of research to improve health by giving an incomplete body of evidence. We aimed to show the effect of the bias towards statistical significance on the evidence-base using published confidence intervals. We examined over 968,000 ratios and their confidence intervals in the abstracts of health and medical journals from Medline between 1976 and January 2019. We plotted the distributions of lower and upper confidence interval limits to visually show the strong bias for statistically significant results. There was a striking change in the distributions around 1, which is the statistically significant threshold for ratios. There was an excess of lower intervals just above 1, corresponding to a statistically significant increase in risk. There was a similar excess of upper intervals just below 1, corresponding to a statistically significant decrease in risk. These biases have not improved in recent years. The huge excesses of confidence intervals that are just above and below the statistically significant threshold are not statistically plausible. Large changes in research practice are needed to provide more results that better reflect the truth.