bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing Vocational High School EFL Teachers’ Technological Pedagogical Content Knowledge in Online Learning
Authors: Indriyono Happy , Budiraharjo Markus , Bram Barli
Published: October 2022

During the Covid-19 pandemic, classroom activities are mostly conducted online using Information and Communication Technology (ICT). This situation requires teachers to be literate in technology for teaching. Some pedagogical methods and platforms are available to support learning activities and a number of constraints need resolving. This study aimed to investigate the empirical data of teachers’ readiness for English education in vocational high school considering the technology integration in teaching and to uncover the obstacles. Teachers’ readiness was assessed using Mishra and Koehler’s (2006) Technological Pedagogical Content Knowledge (TPACK) framework. Descriptive quantitative research was conducted to the members of the forum of vocational high school English teachers located in Surakarta. It was predicted that a number of English teachers participating in this research were not ready for technology integration in the future in spite of their strong desire to learn the technology. Based on the participants’ responses, it was also crucial to have supports from educational institutions where teachers worked to provide relevant devices and encouraging atmosphere to enable technology-enhanced learning. It was predicted that students’ primary impediments to learning with technology were the facilities and the teacher’s pedagogical methods.
The Correlation between EFL Students’ Vocabulary Knowledge and Reading Comprehension
Authors: Manihuruk David Hotmagasi
Published: October 2022

This study aimed at investigating the correlation between students ’vocabulary mastery and reading comprehension performance. The population of the study was the whole students at the English Education Department of Universitas Kristen Indonesia. The sample was taken using the cluster sampling technique, i.e., by taking 52 students of Batch 2015, 2016, and Batch 2017 as the participants. Data were collected in May 2019 by administering vocabulary mastery and reading comprehension tests. The instrument’s reliability was tested employing Cronbach Alpha with the results of 0.733 for the vocabulary test and 0.730 for the reading comprehension test, indicating both instruments are reliable. Using Spearman's non-parametric test, the correlation coefficient between the two variables at the sig. (2 tailed) and 0.05 level of significance was 0.014.  This indicates there is a positive moderate correlation between vocabulary knowledge and reading comprehension.
Teaching Technique: Inside Outside Circle on Students’ Writing Skill of Secondary School in Tangerang
Authors: Yanah Mulyanah Euis
Published: October 2022

This research is aimed to find out the effect of the inside outside circle on tenth-grade students' writing narrative text at SMAN 3 Kabupaten Tangerang in the academic year 2019/2020. This research used a quasi-experiment with pre-test and post-test design. The technique of teaching used in this research is the inside outside circle. The population is 416 students at the school, and the sample was purposively selected by taking two classes of the tenth grade, each consists of 30 students The data was analyzed by using a T-test at the level significance (α=0.05) and degree of freedom is 58. The result showed that the t-count was higher than the t-table (4.49 > 2.00). In other words, the null hypothesis (H0) is rejected and the hypothesis alternative (Ha) is accepted. It means that the inside outside circle technique can improve the students' writing narrative score and the students will be easier to write because it can improve students' ideas. So, the inside outside circle is recommended to be applied for teaching writing.
Students’ Perception In Learning English Vocabulary Through Quizlet
Authors: Aprilani Dea Nur , Suryaman Maman
Published: October 2022

Vocabulary learning in second and/or foreign languages is needed to make effective communication and it is impossible to use a language effectively without an adequate vocabulary and to master other skills in English. However, many senior high school students have poor knowledge of vocabulary mastery because the process of remembering vocabulary is considered bored and stressful. This study is focused to investigate the student perceptions of the use of Quizlet in learning English vocabulary. The total participation is five students from senior high school. The interview was used to obtain information and explanations related to the student perceptions of learning English vocabulary. The data was analyzed through thematic analysis for classification and summary purposes. The results showed that Quizlet is effective to learn vocabulary interestingly and it makes the students felt more enthusiastic in learning English vocabulary. Accordingly, this research recommends English teachers use Quizlet in teaching English vocabulary to students in the classroom.
The Relationship between Students’ Speaking Skill and Students’ Self-Esteem of Mover F Class of NCL Madiun
Authors: Dewi Istyaning Asifa , Widiyani Erlik , Kurniawan Arri
Published: October 2022

The purpose of this study is to know "The Relationship between Students' Speaking Skills and Students' Self-Esteem of NCL Madiun's Mover F Class." This study's problem formulation is whether there is a relationship between students' speaking skills and NCL Madiun's mover class students' self-esteem. The purpose of this study was to determine whether there was a relationship between students' speaking ability and self-esteem in the NCL Madiun mover class. Mover F class NCL Madiun students took part in this study. There are 180 students in the NCL Madiun Mover class, which is divided into ten classes. The purposeful sampling technique was used in this study, and the sample consisted of 19 students from Mover F class, with 12 boys and 9 girls. The type of data used is quantitative data. Data were gathered using speaking tests and self-esteem questionnaires. According to the findings, the average score for speaking skills was 73.53, while the average value for self-esteem was 72. Pearson's product-moment correlation produces 797 results and a sig value of less than 0.05, corresponding to 0.0001. The researcher comes to the conclusion that H1 is accepted and H0 is rejected, implying that there is a relationship between students' speaking abilities and self-esteem in the NCL Madiun Mover F class. Students who have high self-esteem outperform students who have low self-esteem.
Pre-Service EFL Teachers’ Perception of Using Podcast as a Learning Media to Improve Listening Skills
Authors: Hasibuan Mawar Estepani , Male Hendrikus
Published: October 2022

The podcast is one of the popular tools of technology that can be used to support English language learning, especially in listening skills. Students can access podcasts everywhere and anytime to train their listening skills. Therefore, this study was employed to investigate the pre-service EFL teachers' perception of using podcasts as a learning medium in improving listening skills. The study was conducted on students of the English Language Education Department of Universitas Kristen Indonesia in May 2021. The respondents of this study were 50 students in the 2017-2019 batches. This study collected the quantitative data by distributing a questionnaire that consisted of 30 items. The data obtained were analyzed by using descriptive statistics. The result of this study showed that students hold a positive perception of using Podcasts as a learning medium in improving listening skills. Therefore, podcasts can motivate the students to become better listeners, and more confident when listening to the native speaker in the Podcast. The findings also indicated that it is essential for teachers to use appropriate instruction to achieve the best results. This media will assist both the teacher and the students in the learning process.
Thermostable heat-insulating composite materials based on hollow microspheres and solid phosphate binders: development and research
Authors: Apanasevich Natalia S. , Sokal Aliaksei A. , Kudlash Alexander N. , Lapko Konstantin N. , Siomikha Alesia Yu. , Yerakhavets Aliaksandra M.
Published: October 2022

Thermostable heat-insulating composite materials based on solid magnesium phosphate and calcium phosphate binders, fly-ash and glass hollow microspheres have been developed and proposed. Thermal and phase transformations have been studied as well as strength characteristics of the initial composites and products of their thermal treatment up to 1000 °C have been determined. It is shown that the prepared phosphate composites are thermally stable in the temperature range of 20 –1000 °С, have a density 0.4 – 0.6 g/cm3 , thermal conductivity 0.11– 0.19 W/(m ⋅ K) and show sufficiently high strength properties (compressive strength 1.4 –3.2 MPa).
Green chemistry teaching: Belarusian view through world tendencies
Authors: Savitskaya Тatsiana A. , Liavontsyeu Aliaksei P. , Kimlenka Iryna M. , Grinshpan Dmitry D. , Drashar Pavel , Lam Tran Dai , Lan Pham Thi
Published: October 2022

The disciplines curricula on green chemistry and sustainable chemistry available in various universities of the world were analysed. Trends in education development and science in this particular area were described as well as actual green chemistry teaching problems that need to be solved. Analysing the data obtained three approaches defining a trajectory for teaching the basic foundations of green chemistry were identified: British, European, and American. The first one involves in-depth study and the formation of competencies in the field of green chemistry. The second approach implies the inclusion of green chemistry in traditional chemical disciplines (organic, analytical chemistry, etc.). The third approach implies the inclusion of green chemistry as a module in such practice-oriented disciplines as biotechnology, food safety, ecology, etc. The content of the laboratory classes in green chemistry curricula and the usage of a green chemistry metric «green star» for assessment of their safety are discussed. It is proposed to join efforts of different countries for green chemistry ideas promotion and transfer the green chemistry ideas through creation of green chemistry centers of excellence for the use of its principles and methods in scientific research and the educational process.
Current Perspectives and Future Directions of Repeat Pulmonary Rehabilitation Programmes in People with Chronic Obstructive Pulmonary Disease: A Narrative Review of the Literature
Authors: McNamara Renae , Dale Marita , Spencer Lissa
Published: October 2022

The benefits of pulmonary rehabilitation (PR) diminish over 12–24 months following programme completion. A repeat PR programme may potentially prevent or reverse this decline in gains and may provide additional benefits. The aim of this narrative review was to discuss the current available evidence regarding repeat PR programmes and provide perspectives on unresolved questions, future areas of inquiry, and suggestions for clinical practice. Randomised controlled trials showed PR repeated at 6, 12, or 24 months after the initial PR programme resulted in similar short-term improvements in exercise capacity and quality of life; however, they did not result in long-term benefits beyond 12–24 months. In uncontrolled studies, the improvements in exercise capacity achieved following repeat PR were of a smaller magnitude than after the initial PR programme, but the improvements were still clinically significant. There is limited evidence to guide the optimal timing and characteristics of a repeat PR programme, such as frequency, duration and content, as well as which patients may benefit. There are ethical factors to consider in offering repeat PR programmes, including availability and access, the impact on resources and capacity of PR programmes, and patient-related factors such as financial burden and difficulties with transport. Alternate means of delivering a repeat PR programme should be explored, especially with emerging evidence for home-based PR and telerehabilitation programmes. A modular approach to a repeat PR programme by offering only certain elements rather than a comprehensive programme may also address the aspects of access, resources, capacity, and patient burden.
Pollen Exposure Increases the Risk of Respiratory Symptoms in Infants: A Longitudinal Study
Authors: Gisler Amanda , Eeftens Marloes , de Hoogh Kees , Vienneau Danielle , Salem Yasmin , Yammine Sophie , Jakob Julian , Gorlanova Olga , Decrue Fabienne , Gehrig Regula , Frey Urs , Latzin Philipp , Usemann Jakob
Published: October 2022

Exposure to pollen has been associated with an increased risk of respiratory symptoms in both allergic and nonallergic individuals. However, the association of pollen exposure with respiratory symptoms during infancy, a particularly vulnerable period for lung development, remains unclear. The goal of this study was to examine whether pollen exposure is associated with respiratory symptoms (cough, wheezing, and dyspnoea) during the first year of life and to test if maternal atopy, infant’s sex, and air pollution modify this association.
Re-IMAGinING the Pathway for Clinical Decision Making in Rare Lung Diseases: Moving Towards a United Vision
Authors: Humphry Nicola , Stolz Daiana , Strange Charlie , Wijsenbeek Marlies S. , Estes Elizabeth , McElvaney Gerry
Published: October 2022

This industry-supported symposium was held during the European Respiratory Society (ERS) International Congress and included presentations from several internationally renowned experts in rare lung diseases. The panel discussed the need to improve clinical decision making to expedite disease recognition, prognostic prediction, and early treatment in interstitial lung disease (ILD) and alpha 1 antitrypsin (AAT) deficiency-related chronic obstructive pulmonary disease (COPD).

Daiana Stolz, Clinic for Pneumology, University Hospital Freiburg, Switzerland, and Marlies S. Wijsenbeek, Erasmus University Medical Centre, Rotterdam, the Netherlands, explained that although high-resolution CT (HRCT) scans may appear similar, ILD from different causes results in significantly different patient outcomes. Therefore, image analysis and the identification of sensitive and specific biomarkers are critical to improving diagnosis and monitoring treatment response and disease progression in ILD.

Charlie Strange, Medical University of South Carolina, Charleston, USA, and Gerry McElvaney, Irish Centre for Genetic Lung Disease, Dublin, Ireland, described the variability in CT-based lung density measurements used to assess the progression of emphysema in patients with AAT deficiency. Clinical trial data indicate that accurate CT lung density measurements are superior to lung function measurements and other endpoints to detect disease progression. However, Strange presented data that showed the considerable impact of acute exacerbations of COPD on CT imaging measurements.

One organisation working to improve the accuracy and value of imaging data in lung diseases is the Open Source Imaging Consortium (OSIC), Saugatuck, Michigan, USA. Elizabeth Estes, who works for OSIC, explained that OSIC aims to build a large, global database of anonymised patient data and CT images in ILD, with plans for future expansion into other rare lung diseases. The ultimate goals of this effort are to encourage collaboration, and to develop machine learning algorithms to improve clinical decision making in rare lung diseases.
Application of particle streak velocimetry based on binocular vision in cascade flow channel
Authors:   1 School of Energy and Power Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China, Feng Mingjun ,   2 Shanghai Key Laboratory of Multiphase Flow and Heat Transfer for Power, Zhou Wu ,   1 School of Energy and Power Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; 2 Shanghai Key Laboratory of Multiphase Flow and Heat Transfer for Power, Wang Fangting ,   1 School of Energy and Power Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; 2 Shanghai Key Laboratory of Multiphase Flow and Heat Transfer for Power
Published: October 2022

Particle streak velocimetry (PSV) has become one of the important branches of measurement methods for fluid flow. A new kind of particle streak velocimetry method based on binocular vision and single-frame multi-exposure technology is proposed. The direction of the flow is judged by the combination of short and long exposures, the gray-level fitting method is used to identify the trajectory features. This method uses nearest neighbor matching and angle of inclination constraints to match and sort multiple trajectories of the same particle, uses epipolar constraints to accomplish binocular matching based on trajectory feature points, and adopts B-spline fitting on the three-dimensional reconstructed feature points to calculate the three-dimensional velocity of particles. The actual measurement of the fluid flow in a gas pipeline shows that this method can be reliably used for unsteady flow measurement.
Numerical Investigation of the Reynolds Number Effect on Five-Hole Probe Calibration
Authors:   University of Michigan- Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University, Fan Weihan , Xie Wenbo ,   University of Michigan- Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University, Jiang Hongmei ,   University of Michigan- Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University, Lu Shaopeng ,   School of Aeronautics and Astronautics, Shanghai Jiao Tong Unversity, Zhang Yuze ,   University of Michigan- Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University, Zhang Qiang ,   University of Michigan- Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University
Published: October 2022

Five-hole probes are widely used in turbomachinery applications. However, the Reynolds number dependence of the probe calibration has not received enough attention. The experimental uncertainty remains unclear when a probe is applied to wind tunnel measurement with a Reynolds number range different from its calibration condition. This numerical study investigated the sensitivity of five-hole probe calibration for a range of Reynolds numbers (4500-138000). The detailed flow physics around five-hole probe tip at various flow regimes (incompressible flow and high subsonic flow) were analyzed. The deviation of surface pressure distribution and calibration coefficients at different Reynolds numbers were quantitatively evaluated. The results reveal that, two counter-rotating vortices are generated at probe tip at large flow angles, and regions affected by vortices vary much in pressure coefficient at different Reynolds numbers. A recommended region of hole positioning is found according to flow structure and calibration results. At lower Mach number, the calibration becomes more sensitive to Reynolds number, while at high Reynolds number range this sensitivity becomes lower. Also, a rounded front edge design of a five-hole probe is found to have higher Reynolds number sensitivity than a sharp front edge design. The present study provides a useful guidance to five-hole probe calibration strategy and probe geometry design, and also highlights the need for in-situ calibration rig development, particularly in turbomachinery experimental studies.
Development of Aspirated Ultra-Short Intakes for Aerodynamic Off-Design Analysis
Authors:   Institute of Jet Propulsion and Turbomachinery, TU Braunschweig, Harjes Lennart , Benjamin Legin ,   Institute of Jet Propulsion and Turbomachinery, Grubert Jonas ,   Institute of Jet Propulsion and Turbomachinery, Heykena Constance ,   Institute of Jet Propulsion and Turbomachinery, Friedrichs Jens ,   Institute of Jet Propulsion and Turbomachinery
Published: October 2022

Even with different energy storage systems and power technologies of future aircraft, the thrust performance will be implemented with propulsors. In this context, the off-design nacelle behaviour – in particular for pure crosswind tests – becomes increasingly important especially for ultra-short nacelle designs due to their supposed drag and weight benefits [Peters and Rose (2015)]. In the upcoming years, several experimental tests at the Propulsion Test Facility (PTF) in Braunschweig are planned, to investigate the intake performance for different scale sizes and aspirated/powered test setups. As a starting point, two axisymmetric nacelles differing in intake length were designed and optimized at a representative full-scale fan diameter using an intuitive class/shape transformation based parametrization. The length was varied between L/D = 0.49 (classical design) and L/D = 0.36 (short design) with a minimum cruise drag design objective. The work flow of the optimization algorithm and nacelle parameter trends analysis are presented. Both intakes are scaled down to the testing rig’s diameter for the off-design analysis and a numerical setup and mesh density study are conducted. Through a detailed analysis of crosswind and scaling effects on the intake aerodynamics, the full-scale designs are modified to deliver a similar distortion behaviour for both designs by adapting the contraction ratio of the intakes. As a preparation for the upcoming tests, the numerical results of the local lip aerodynamics were analyzed for both intake designs showing, inter alia, that a decrease of the intake length increases the aerodynamic loading at the throat for the windward section.
Machine Learning Based Design Optimization of Centrifugal Impellers.
Authors:   Dalian University of Technology, Zhang Ao , Liu Yan ,   Dalian University of Technology, Yang Jinguang ,   Dalian University of Technology, Li Zhi ,   Dalian University of Technology, Zhang Chuang ,   Dalian University of Technology, Li Yiwen ,   Shenyang Blower Works Group
Published: October 2022

The big data and machine learning are developing rapidly, and their applications in the aerodynamic design of centrifugal impellers and other turbomachinery have attracted wide attention. In this paper, centrifugal impellers with large flow coefficient (0.18-0.22) are taken as research objects. Firstly, through one-dimensional design and optimization, main one-dimensional geometric parameters of those centrifugal impellers are obtained. Subsequently, hundreds of samples of centrifugal impellers are obtained by using an in-house parameterization program and Latin hypercube sampling method. The NUMECA software is used for CFD calculations to build a sample library of centrifugal impellers. Then, applying the artificial neural network (ANN) to deal with the he data in the sample library, a nonlinear model between the flow coefficients, the geometric parameters of these centrifugal impellers and the aerodynamic performance is constructed, which can replace the CFD calculation. Lastly with the help of the multi-objective genetic algorithm, a global optimization is carried out to fulfull a rapid design optimization for centrifugal impellers with flow coefficients in the range of 0.18- 0.22. Three examples provided in the paper show that the design and optimization method described above is faster and more reliable compared with the traditional design method. This method provides a new way for the rapid design of centrifugal impellers.
Research on Aerodynamics and Aeroacoustics of Duct Fan based on Panel-Vortex Particle Method
Authors:   nwpu.edu.cn, Liu Qian , Liu Hanru ,   nwpu.edu.cn, Wang Haitong ,   nwpu.edu.cn, Li Jiahui ,   nwpu.edu.cn, Wang Yangang ,   nwpu.edu.cn
Published: October 2022

With the urge requirement of high-performance aircraft electric propulsor, duct fan is expected to work in different operation conditions efficiently and satisfying multiple targets constraint. However, the putting up of higher design standards means FEM or FVM will be unsuitable because of the high computational cost. To achieve a balance between computational cost and accuracy, especially an unsteady aerodynamic problem e.g. aeroacoustics/aeroelasticity, the highefficiency Panel-Vortex Particle Method (PVM) is developed to predict the aerodynamic performance of a duct fan. Then, the duct acoustic model is developed to complete the acoustics prediction of duct fan. The hybrid method, consisting PVM and duct acoustic model, can be used to get a similar thrust with error of 0.93% when the span ratio of mesh is less than 91.6%, when comparing with FVM results. But the thrust of blade tip is over-predicted, which causes a total error of 5.36%, and the SPL is in a relative error of 4.16% under 1BPF and 11.55% under 2BPF.
INVESTIGATION OF LOCK-IN PHENOMENON OF A FLE FAN
Authors:   School of Energy and Power Engineering Beihang University, Zheng Yun , Gao Qingzhe ,   School of Energy and Power Engineering Beihang University, Yang Hui ,   School of Energy and Power Engineering Beihang University, Lei Da ,   School of Energy and Power Engineering Beihang University
Published: October 2022

This study numerically investigates the lock-in phenomenon of a fan blade with a flat-tip leading edge. A fully coupled, fluid-structure interaction method was applied to obtain the unsteady flows coupled with the blade vibrations. The results show that the disturbances of the unsteady aerodynamics become locked to the structural vibration, which indicates a lockin phenomenon. For a fixed modal velocity as the initial excitation, the frequencies of the structured mode were altered around the natural frequency to determine the lock-in boundary. In the lock-in region, the vibration amplitude grew exponentially, thus the blade vibration was unstable. The spectra of the displacement and the unsteady pressure associated with the structural response and the aerodynamic disturbance exhibit discrete peaks. The absolute difference of the coupled aerodynamic wave number (AWN) and the nodal diameter (ND) was equal to the blade number. In the unlocked region, the blade vibration exhibits the characteristics of the limit cycle oscillation. The pressure spectra present broadband peaks and the AWN was not matched to the concerned ND. However, the AWN and the ND changed in the cases with different vibration frequencies, and it indicates that there was still a coupling between the aerodynamic disturbance and the structural vibration. The lock-in phenomenon was consistent with the occurrence of NSV, evidenced by the fact that the frequency and phase of the aerodynamic disturbance can be locked to the structural vibration pattern. Hence, NSV could be induced by the lock-in phenomenon.
INVESTIGATIONS ON THE EFFECTS OF FLUE GAS RECIRCULATION ON THE COMBUSTION INSTABILITY OF A PREMIXED FLAME FOR THE LOW NOX EMISSIONS
Authors:   Tongji University, Pan Deng , Zhu Tong ,   Tongji University, Ji Chenzhen ,   Tongji University
Published: October 2022

The combustion instability has been a common problem accompany with the low NOx emission technologies in industrial premixed burner. The effects of flue gas recirculation ratio (FR) on the characteristics of combustion instability and NOx emissions of an industrial scale premixed burner were investigated with experiments and numerical simulation. The acoustic mode of the whole chamber was computed with a Helmholtz solver combined with CFD simulation. The NOx emissions significantly decrease with the increasing of the FR. As FR increases from 0% to 20% the NOx emission reduces about 85%. Four modes of pressure oscillations in the combustion chamber with different FRs were found in the experiment. The pressure oscillation exhibits combustion noise mode at low FRs (<10%) in which conditions the pressure oscillation amplitude is low and there is no distinct frequency. Two dominant pressure oscillation frequency ranging from 21Hz to 25Hz and ranging from 1Hz to 2Hz are observed under relatively high FRs. The first acoustic mode frequency is 5.3Hz~5.7Hz and the second acoustic mode frequency is 23.1Hz~24.1Hz which are close to the pressure oscillation frequencies observed in the experiment. The ultra-low frequency and high amplitude pressure oscillations are attributed the periodic overall extinguish and ignition of the flame under high FRs. The difference between the pressure oscillation frequencies and the acoustic cavity mode frequencies may be attributed to the interaction of the response of the flame and the cavity acoustic mode which can lead to mode transition.
Numerical Investigations on Slip Characteristics and Slip Onset Position in High-Loaded Backswept Centrifugal Impellers
Authors:   University of Shanghai for Science and Technology, School of Energy and Power Engineering, Zhang Chaowei , Dong Xuezhi ,   Institute for Aero Engine, Tsinghua University, Liu Xiyang ,   Institute for Aero Engine, Tsinghua University, Zhang Hualiang ,   1. Institute of Engineering Thermophysics, Chinese Academy of Sciences 2. University of Chinese Academy of Sciences
Published: October 2022

This paper mainly investigates the effect of mass flow, blade turning and tip clearance size on the slip characteristics in the high-loaded backswept centrifugal impeller by numerical simulation. The numerical results show that the slip onset position mainly depends on the blade loading and the intensity of tip leakage flow. The mass-averaged slip onset position moves upstream but changes little with increased mass flow. The mass-averaged slip onset position is very close to the position of the peak value in the B2B blade loadings at the design condition. With increased exit blade angle, the mass-averaged slip onset position moves downstream and the mass-averaged slip factor increases. With increased tip clearance size, the mass-averaged slip onset position moves downstream first and then upstream. This study can supply some guidance to develop the slip onset position prediction model for high-loaded backswept centrifugal impellers.
OPTIMASI PENGGUNAAN HPMC DAN Na CMC PADA FORMULA TRANSDERMAL PATCH EKSTRAK ETANOL BUNGA TELANG (Clitoria ternatea L.) DENGAN METODE SIMPLEX LATTICE DESIGN
Authors: Saryanti Dwi , Putri Setyadi Ita Mustika
Published: October 2022

Transdermal patch is drug delivery system that is pasted through the skin. These preparations can provide a constant drug release, easy to use, reduce the frequency of drug administration, eliminate first-pass metabolism, and reduce side effects such as gastric irritation and improve patient compliance. Blue pea (Clitoria ternatea L.) contains flavonoid compounds that have anti-inflammatory activity. This study aims to obtain the optimal comparison of HPMC and Na CMC as a polymer in the transdermal patch formula of the ethanol extract of the blue pea (Clitoria ternatea L.). Optimization was carried out using the Simplex Lattice Design method with Software Design Expert version 11. The responses used included pH tests, weight tests, thickness tests, folding tests and moisture content tests. The optimal formula obtained from the Simplex Lattice Design method was verified with the SPSS program using the one sample t-test method. The optimal formula of transdermal patch of blue pea ethanol extract was tested for acceptability to determine whether it was acceptable to the respondent or not. The optimal comparison of HPMC and Na CMC as a polymer with transdermal patch preparation of blue pea ethanol extract was 3.5%:1%, with a desirability value of 0.944.
UJI RESISTENSI BAKTERI Escherichia coli DARI SUMBER AIR BAKU DI KARAWANG TERHADAP ANTIBIOTIK SIPROFLOKSASIN
Authors: Diniarti Fuji Ayu , Kasasiah Ahsanal , Hilmi Indah Laily
Published: October 2022

Infectious diseases are included in the ten most common diseases in Indonesia. The disease can be overcome by the use of antimicrobials, one of which is antibiotics. Antibiotics are drugs used to treat infections caused by bacteria. Excessive use of antibiotics without clear indications can have an impact on the occurrence of bacterial resistance to these antibiotics. One of the bacteria that is resistant to antibiotics is Escherichia coli. This study aims to determine the sensitivity of Escherichia coli isolated from raw water sources in Karawang to the antibiotic ciprofloxacin. Samples were obtained from irrigation water which is the source of raw water for one branch of Perumdam in Karawang. The samples were tested using Lactose Broth (LB) media, then confirmed using Eosin Methylene Blue (EMBA) media to confirm the presence of Escherichia coli bacteria equipped with Gram stain. Bacterial resistance test was carried out using Mueller Hinton Agar (MHA) media with disc diffusion method. The results showed that the average diameter of the clear zone formed around the paper disc was 30.16 mm. The isolates showed intermediate results against the antibiotic ciprofloxacin.
FORMULASI DAN EVALUASI FISIK MASKER GEL PEEL OFF DARI SERBUK SISIK IKAN MUJAIR (Oreochromis mossambicus)
Authors: Mutmainnah Mutmainnah , Abdullah Abulkhair , Syawie Muvida
Published: October 2022

Masker gel peel off merupakan salah satu kosmetik yang digunakan untuk perawatan kulit yang dapat memutihkan, mengecilkan pori-pori, melembabkan dan menutrisi kulit. Salah satu bahan yang dapat dijadikan bahan utama masker gel peel off adalah sisik ikan mujair (Oreochromis mossambicus). Sisik ikan mujair mengandung kolagen yang bermanfaat sebagai antiaging. Penelitian ini bertujuan untuk mendapatkan formula masker gel peel off dari sisik ikan yang terbaik dengan memvariasikan konsentrasi PVA (5% dan 10%) dan HPMC (2% dan 4%). Dalam penelitian ini dibuat 4 formula yang berbeda. Pada sediaan dilakukan pengujian karakteristik yang meliputi uji organoleptis, uji homogenitas, uji pH, uji daya sebar, uji waktu mengering, dan uji hedonik. Hasil penelitian menunjukkan sediaan yang dibuat sudah memenuhi kriteria. Semua formula memiliki tekstur semi padat, beraroma jeruk, dan berwarna abu-abu dan semua formula menunjukkan homogenitas yang baik. Hasil uji pH diperoleh: F1 (5,0), F2 (5,6), F3 (5,5), dan F4 (5,4). Hasil uji daya lekat diperoleh: F1 (400 g : 5,2 cm), F2 (600 g : 5,2 cm), F3 (600 g : 5,4 cm), dan F4 (600 g : 5,4 cm). hasil uji waktu mengering: F1 (55 menit), F2 (33 menit), F3 (33,3 menit), F4 (56,3 menit). Dapat disimpulkan bahwa serbuk sisik ikan mujair dapat dijadikan sediaan masker gel peel off. Formula 2 menjadi formula terbaik dengan konsentrasi PVA 10% dan HPMC 2%.
PENGARUH KOMBINASI SODIUM LAURIL SULFAT DAN NATRIUM KLORIDA TERHADAP KARAKTERISTIK SAMPO EKSTRAK LIDAH BUAYA
Authors: Andriani Luh Nela , Putra I Gusti NAWW , Tunas I Ketut
Published: October 2022

The shampoo industry in Indonesia is growing. The shampoo formulation contains 2 main ingredients, namely sodium lauryl sulfate (SLS) and sodium chloride (NaCl). One example of natural ingredients in the manufacture of shampoo is Aloe Vera (Aloe vera L.). This study aims to determine the effect of variations in the concentration of SLS and NaCl on the physical and chemical properties of shampoo. This research is an experimental study with 8 formulas. Includes organoleptic test, homogeneity test, viscosity test, foam height test, specific gravity test, and pH test. Making shampoo preparations by weighing all ingredients according to each formulation, leaving the shampoo for 1 day before testing for 4 weeks of storage.The results showed that the organoleptic test and the homogeneity test of NaCl and SLS had no effect on shampoo. In the specific gravity test and the pH test of NaCl and SLS there was no dominant influence on the specific gravity of shampoo. In the foam height test, the SLS coefficient value is higher than NaCl so that SLS dominantly affects the height of the shampoo foam. In the viscosity test the coefficient value of NaCl is higher than SLS so that NaCl dominantly affects the viscosity of the shampoo. The conclusion from this research is that NaCl has a dominant influence on the physical properties, namely viscosity, while SLS has a dominant influence on the physical properties, namely the height of the shampoo foam.
Pengaruh Parenting Self-Efficacy, Keterlibatan Orang Tua dalam Pembelajaran Online dan Tiingkat Pendidikan Orang Tua terhadap Hasil Belajar Siswa
Authors: Tumbol Franky Anatoly , Kho Ronaldo
Published: October 2022

During the COVID-19 pandemic students had to learn at home. In this mode of learning students experienced difficulties in understanding the learning material which impacted on student assignments completion. This condition requires parental involvement in solving the problem. Parental background has effects on the quality of student mentoring. This study aims to determine the impact of parenting self-efficacy, parental involvement in online learning, and parental education level on student learning outcomes. The population of this study was all parents (mothers) of active students enrolled in the school. This research uses ex post facto research. The Measurement of variabels using a Likert Scale with multiple regression analysis. The results show that the variabel that has the most influence on student learning outcomes is the level of parental education which contributes 68.3%, followed by the variabel of parental involvement of 22.5% and the variabel of parenting self-efficacy of 9.2%.
Prinsip-Prinsip Pendidikan Anak Dalam Ulangan 6:4-9
Authors: Astuti Sri , Silalahi Desi Sutresia
Published: October 2022

The problem in this paper lies in the principles of child education contained in the Israel Shema. This discussion aims to First, the author can find out how the Israeli concept of children and the significance of children's education for the Israelites; Second, the writer knows the method or method applied by Israeli parents in educating their children; Third, the author can explore and describe the principles of child education contained in Deuteronomy 6:4-9. So this paper uses a library research approach. The conclusion of this paper proves that first, first, the nation of Israel is a nation that prioritizes education for children, because for the Jewish nation children are a precious gift from God. Second, in the Jewish tradition the family is the first and foremost place of education for children. The pattern used by Israeli parents in educating their children is by bringing their children to attend worship rituals, namely religious activities in houses of worship or celebrating religious holidays with the family, so that children have direct experience with God through worship, as well as using symbols. In addition, the methods used are verbal and non-verbal methods. Third, three important things are the principles of Shema written in Deuteronomy 6:4-9, namely loving God, educating children is the responsibility of parents, and repeated teaching.

 

 

Abstrak Bahasa Indonesia 

Permasalahan dalam tulisan ini terletak pada Prinsip-prinsip pendidikan anak yang terkandung dalam Shema Israel. Pembahasan ini bertujuan untuk Pertama, penulis dapat mengetahui bagaimana konsep orang Israel tentang anak dan signifikansi pendidikan anak bagi bangsa Israel; Kedua, penulis mengetahui cara atau metode yang diterapkan oleh orangtua Israel dalam mendidik anak; Ketiga, penulis dapat menggali dan menguraikan prinsip-prinsip pendidikan anak yang terkandung dalam Ulangan 6:4-9. Maka tulisan ini menggunakan pendekatan penelitian kepustakaan. Kesimpulan tulisan ini membuktikan bahwa pertama, Pertama, bangsa Israel merupakan bangsa yang sangat mengutamakan pendidikan kepada anak, sebab bagi bangsa Yahudi anak adalah anugerah berharga dari Allah. Kedua, dalam tradisi Yahudi keluarga merupakan tempat pendidikan pertama dan yang utama bagi anak. Pola yang digunakan orang tua Israel dalam mendidik anak yaitu dengan membawa anak untuk mengikuti ritual ibadah, yaitu kegiatan keagamaan di rumah ibadah maupun merayakan hari raya keagamaan bersama keluarga, sehingga anak memiliki pengalaman langsung dengan Allah melalui ibadah, juga menggunakan simbol-simbol. Selain itu, metode yang digunakan adalah metode verbal dan non verbal. Ketiga, tiga hal penting yang menjadi prinsip pendidikam Shema yang tertulis di dalam Ulangan 6:4-9, yaitu mengasihi Allah, pendidikan anak adalah tanggung jawab orang tua, dan pengajaran berulang-ulang.
The therapeutic effect of adipose-derived lipoaspirate cells in femoral head necrosis by improving angiogenesis
Authors: Zhang Weixin , Zheng Cheng , Yu Tiefeng , Zhang Houjian , Huang Jiaxin , Chen Liyue , Tong Peijian , Zhen Gehua
Published: October 2022

Femoral head necrosis (FHN), one of the most popular joint diseases in the musculoskeletal system, is usually attributed to local ischemia of the femoral head. Thus, regenerating the vascularization capacity and restoring the local perfusion of the femoral head becomes an efficient therapeutic approach for FHN. We investigated the function of autologous lipoaspirate cells (LPCs) in regenerating circulation in FHN animal models and human subjects in this study. We also explored the mechanisms of why LPCs show a superior effect than that of the bone marrow-derived stem cells (BMSCs) in vascularization. Thirty-four FHN patients were recruited for the randomized clinical trial. Harris Hip Score (HHS) and digital subtraction arteriography (DSA) and interventional technique were used to compare the efficacy of LPCs treatment and vehicle therapy in improving femoral head circulation and hip joint function. Cellular mechanism that underlies the beneficial effect of LPCs in restoring blood supply and rescuing bone architecture was further explored using canine and mouse FHN animal models. We found that LPCs perfusion through the medial circumflex artery will promote the femoral head vascularization and bone structure significantly in both FHN patients and animal models. The HHS in LPCs treated patients was significantly improved relative to vehicle group. The levels of angiogenesis factor secreted by LPCs such as VEGF, FGF2, VEC, TGF-β, were significantly higher than that of BMSCs. As the result, LPCs showed a better effect in promoting the tube structure formation of human vascular endothelial cells (HUVEC) than that of BMSCs. Moreover, LPCs contains a unique CD44+CD34+CD31− population. The CD44+CD34+CD31− LPCs showed significantly higher angiogenesis potential as compared to that of BMSCs. Taken together, our results show that LPCs possess a superior vascularization capacity in both autonomous and paracrine manner, indicating that autologous LPCs perfusion via the medial circumflex artery is an effective therapy for FHN.
'Targeting' the search: An upgraded structural and functional repository of antimicrobial peptides for biofilm studies (B-AMP v2.0) with a focus on biofilm protein targets
Authors: Ravichandran Shashank , Avatapalli SaiSupriya , Narasimhan Yatindrapravanan , Kaushik Karishma S. , Yennamalli Ragothaman M.
Published: October 2022

Bacterial biofilms, often as multispecies communities, are recalcitrant to conventional antibiotics, making the treatment of biofilm infections a challenge. There is a push towards developing novel anti-biofilm approaches, such as antimicrobial peptides (AMPs), with activity against specific biofilm targets. In previous work, we developed Biofilm-AMP, a structural and functional repository of AMPs for biofilm studies (B-AMP v1.0) with more than 5000 structural models of AMPs and a vast library of AMP annotations to existing biofilm literature. In this study, we present an upgraded version of B-AMP, with a focus on existing and novel bacterial biofilm targets. B-AMP v2.0 hosts a curated collection of 2502 biofilm protein targets across 473 bacterial species, with structural protein models and functional annotations from PDB, UniProt, and PubMed databases. The biofilm targets can be searched for using the name of the source organism, and function and type of protein, and results include designated Target IDs (unique to B-AMP v2.0), UniProt IDs, 3D predicted protein structures, PDBQT files, pre-defined protein functions, and relevant scientific literature. To present an example of the combined applicability of both, the AMP and biofilm target libraries in the repository, we present two case studies. In the first case study, we expand an in silico pipeline to evaluate AMPs against a single biofilm target in the multidrug resistant, bacterial pathogen Corynebacterium striatum, using 3D protein-peptide docking models from previous work and Molecular Dynamics simulations (~1.2µs). In the second case study, we build an in silico pipeline to identify candidate AMPs (using AMPs with both anti-Gram positive and anti-Gram negative activity) against two biofilm targets with a common functional annotation in Pseudomonas aeruginosa and Staphylococcus aureus, widely-encountered bacterial co-pathogens. With its enhanced structural and functional capabilities, B-AMP v2.0 serves as a comprehensive resource for AMP investigations related to biofilm studies. B-AMP v2.0 is freely available at https://b-amp.karishmakaushiklab.com and will be regularly updated with structural models of AMPs and biofilm targets, as well as 3D protein-peptide interaction models for key biofilm-forming pathogens.
Progress in research on gut microbiota in ethnic minorities in China and consideration of intervention strategies based on ethnic medicine: A review
Authors: Chen Rong , Duan Zhong-Yu , Duan Xiao-Hua , Chen Qing-Hua , Zheng Jin
Published: October 2022

One of the variables affecting gut microbiota is ethnicity. There are 56 ethnic subgroups in China, and their intestinal flora differs. A wealth of medical resources has also been produced by the presence of numerous ethnic minorities. In this study, we reviewed the pertinent literature on the intestinal flora of ethnic minorities in China and abroad using the CiteSpace visualization software, and we used bibliometric techniques to find the most widely prescribed medications for preventing and treating endemic diseases in ethnic minorities. Based on the gut microbiology of minority populations, we suggest that by comprehensive development involving literature, experimental, and clinical research, the pharmacological action mechanisms for interventions in endemic diseases can be drawn from ethnic medicine. This point of view has not been discussed before and will offer a fresh perspective on the creation and application of ethnic medications as well as a fresh method for the management of prevalent diseases in ethnic communities.