bluuebunny/crossref_metadata_2025 huggingface dataset:
Probing the Ion Binding Site in a DNA Holliday Junction Using Förster Resonance Energy Transfer (FRET)
Authors: Litke Jacob , Li Yan , Nocka Laura , Mukerji Ishita
Published: March 2016

Holliday Junctions are critical DNA intermediates central to double strand break repair and homologous recombination. The junctions can adopt two general forms: open and stacked-X, which are induced by protein or ion binding. In this work, fluorescence spectroscopy, metal ion luminescence and thermodynamic measurements are used to elucidate the ion binding site and the mechanism of junction conformational change. Förster resonance energy transfer measurements of end-labeled junctions monitored junction conformation and ion binding affinity, and reported higher affinities for multi-valent ions. Thermodynamic measurements provided evidence for two classes of binding sites. The higher affinity ion-binding interaction is an enthalpy driven process with an apparent stoichiometry of 2.1 ± 0.2. As revealed by Eu3+ luminescence, this binding class is homogeneous, and results in slight dehydration of the ion with one direct coordination site to the junction. Luminescence resonance energy transfer experiments confirmed the presence of two ions and indicated they are 6–7 Å apart. These findings are in good agreement with previous molecular dynamics simulations, which identified two symmetrical regions of high ion density in the center of stacked junctions. These results support a model in which site-specific binding of two ions in close proximity is required for folding of DNA Holliday junctions into the stacked-X conformation.
Photochemical Synthesis and Versatile Functionalization Method of a Robust Porous Poly(ethylene glycol methacrylate-co-allyl methacrylate) Monolith Dedicated to Radiochemical Separation in a Centrifugal Microfluidic Platform
Authors: Losno Marion , Ferrante Ivan , Brennetot René , Varlet Jérôme , Blanc Cécile , Grenut Bernard , Amblard Etienne , Descroix Stéphanie , Mariet Clarisse
Published: March 2016

The use of a centrifugal microfluidic platform is an alternative to classical chromatographic procedures for radiochemistry. An ion-exchange support with respect to the in situ light-addressable process of elaboration is specifically designed to be incorporated as a radiochemical sample preparation module in centrifugal microsystem devices. This paper presents a systematic study of the synthesis of the polymeric porous monolith poly(ethylene glycol methacrylate-co-allyl methacrylate) used as a solid-phase support and the versatile and robust photografting process of the monolith based on thiol-ene click chemistry. The polymerization reaction is investigated, varying the formulation of the polymerisable mixture. The robustness of the stationary phase was tested in concentrated nitric acid. Thanks to their unique “easy-to-use” features, centrifugal microfluidic platforms are potential successful candidates for the downscaling of chromatographic separation of radioactive samples (automation, multiplexing, easy integration in glove-boxes environment, and low cost of maintenance).
Functionalization of a Triazine Dendrimer Presenting Four Maleimides on the Periphery and a DOTA Group at the Core
Authors: Lee Changsuk , Ji Kun , Simanek Eric
Published: March 2016

A readily and rapidly accessible triazine dendrimer was manipulated in four steps with 23% overall yield to give a construct displaying four maleimide groups and DOTA. The maleimide groups of the dendrimer are sensitive to hydrolysis under basic conditions. The addition of up to four molecules of water can be observed via mass spectrometry and HPLC. The evolution in the alkene region of the 1H-NMR—the transformation of the maleimide singlet to the appearance of two doublets—is consistent with imide hydrolysis and not the Michael addition. The hydrolysis events that proceeded over hours are sufficiently slower than the desired thiol addition reactions that occur in minutes. The addition of thiols to maleimides can be accomplished in a variety of solvents. The thiols examined derived from cysteine and include the protected amino acid, a protected dipeptide, and native oligopeptides containing either 9 or 18 amino acids. The addition reactions were monitored with HPLC and mass spectrometry in most cases. Complete substitution was observed for small molecule reactants. The model peptides containing nine or eighteen amino acids provided a mixture of products averaging between 3 and 4 substitutions/dendrimer. The functionalization of the chelate group with gadolinium was also accomplished easily.
Prediction of Military Vehicle’s Drawbar Pull Based on an Improved Relevance Vector Machine and Real Vehicle Tests
Authors: Yang Fan , Sun Wei , Lin Guoyu , Zhang Weigong
Published: March 2016

The scientific and effective prediction of drawbar pull is of great importance in the evaluation of military vehicle trafficability. Nevertheless, the existing prediction models have demonstrated lots of inherent limitations. In this framework, a multiple-kernel relevance vector machine model (MkRVM) including Gaussian kernel and polynomial kernel is proposed to predict drawbar pull. Nonlinear decreasing inertia weight particle swarm optimization (NDIWPSO) is employed for parameter optimization. As the relations between drawbar pull and its influencing factors have not been tested on real vehicles, a series of experimental analyses based on real vehicle test data are done to confirm the effective influencing factors. A dynamic testing system is applied to conduct field tests and gain required test data. Gaussian kernel RVM, polynomial kernel RVM, support vector machine (SVM) and generalized regression neural network (GRNN) are also used to compare with the MkRVM model. The results indicate that the MkRVM model is a preferable model in this case. Finally, the proposed novel model is compared to the traditional prediction model of drawbar pull. The results show that the MkRVM model significantly improves the prediction accuracy. A great potential of improved RVM is indicated in further research of wheel-soil interactions.
MAPPING CO GAS IN THE GG TAURI A TRIPLE SYSTEM WITH 50 au SPATIAL RESOLUTION
Authors: Tang Ya-Wen , Dutrey Anne , Guilloteau Stéphane , Chapillon Edwige , Pietu Vincent , Di Folco Emmanuel , Bary Jeff , Beck Tracy , Beust Hervé , Boehler Yann , Gueth Fréderic , Huré Jean-Marc , Pierens Arnaud , Simon Michal
Published: March 2016

We aim to unveil the observational imprint of physical mechanisms that govern planetary formation in the young, multiple system GG Tau A. We present ALMA observations of 12CO and 13CO 3–2 and 0.9 mm continuum emission with 0.″35 resolution. The 12CO 3–2 emission, found within the cavity of the circumternary dust ring (at radius <180 au) where no 13CO emission is detected, confirms the presence of CO gas near the circumstellar disk of GG Tau Aa. The outer disk and the recently detected hot spot lying at the outer edge of the dust ring are mapped both in 12CO and 13CO. The gas emission in the outer disk can be radially decomposed as a series of slightly overlapping Gaussian rings, suggesting the presence of unresolved gaps or dips. The dip closest to the disk center lies at a radius very close to the hot spot location at ∼250–260 au. The CO excitation conditions indicate that the outer disk remains in the shadow of the ring. The hot spot probably results from local heating processes. The two latter points reinforce the hypothesis that the hot spot is created by an embedded proto-planet shepherding the outer disk.
PLUTO’S ATMOSPHERE FROM THE 2015 JUNE 29 GROUND-BASED STELLAR OCCULTATION AT THE TIME OF THE NEW HORIZONS FLYBY*
Authors: Sicardy B. , Talbot J. , Meza E. , Camargo J. I. B. , Desmars J. , Gault D. , Herald D. , Kerr S. , Pavlov H. , Braga-Ribas F. , Assafin M. , Benedetti-Rossi G. , Dias-Oliveira A. , Gomes-Júnior A. R. , Vieira-Martins R. , Bérard D. , Kervella P. , Lecacheux J. , Lellouch E. , Beisker W. , Dunham D. , Jelínek M. , Duffard R. , Ortiz J. L. , Castro-Tirado A. J. , Cunniffe R. , Querel R. , Yock P. C. , Cole A. A. , Giles A. B. , Hill K. M. , Beaulieu J. P. , Harnisch M. , Jansen R. , Pennell A. , Todd S. , Allen W. H. , Graham P. B. , Loader B. , McKay G. , Milner J. , Parker S. , Barry M. A. , Bradshaw J. , Broughton J. , Davis L. , Devillepoix H. , Drummond J. , Field L. , Forbes M. , Giles D. , Glassey R. , Groom R. , Hooper D. , Horvat R. , Hudson G. , Idaczyk R. , Jenke D. , Lade B. , Newman J. , Nosworthy P. , Purcell P. , Skilton P. F. , Streamer M. , Unwin M. , Watanabe H. , White G. L. , Watson D.
Published: March 2016

We present results from a multi-chord Pluto stellar occultation observed on 2015 June 29 from New Zealand and Australia. This occurred only two weeks before the NASA New Horizons flyby of the Pluto system and serves as a useful comparison between ground-based and space results. We find that Pluto's atmosphere is still expanding, with a significant pressure increase of 5 ± 2% since 2013 and a factor of almost three since 1988. This trend rules out, as of today, an atmospheric collapse associated with Pluto's recession from the Sun. A central flash, a rare occurrence, was observed from several sites in New Zealand. The flash shape and amplitude are compatible with a spherical and transparent atmospheric layer of roughly 3 km in thickness whose base lies at about 4 km above Pluto's surface, and where an average thermal gradient of about 5 K km−1 prevails. We discuss the possibility that small departures between the observed and modeled flash are caused by local topographic features (mountains) along Pluto's limb that block the stellar light. Finally, using two possible temperature profiles, and extrapolating our pressure profile from our deepest accessible level down to the surface, we obtain a possible range of 11.9–13.7 μbar for the surface pressure.
Последовательное разбиение ребер двудольного графа на паросочетания
Authors: Magomedov Abdulkarim Magomedovich , Magomedov Tagir Abdulkarimovich
Published: March 2016

Пусть исходные данные к расписанию обслуживания множества требований в некоторой системе приборов заданы двудольным графом. Рассматривается задача составления расписания минимальной длины, удовлетворяющего условиям беспростойной работы каждого прибора и их одновременного ввода в работу. Получены условия разбиения множества ребер графа на паросочетания, образующие расписание требуемого вида. Работа выполнена при финансовой поддержке 1) проекта № 2014/33 в рамках базовой части государственного задания Минобрнауки России, 2) проекта 3с Даггосуниверситета, 3) Отдела математики и информатики ДНЦ РАН.
Prevalence of Type of Frenal Attachment and Morphology of Frenum in Children, Chennai, Tamil Nadu
Authors: Christabel S Linda
Published: March 2016

Background

Labial frenum is a dynamic structure and is subject to variation in size, shape and position. The type of the maxillary labial frenal attachment and its morphology in children in Chennai has not been studied extensively. The purpose of this cross-sectional study is to examine the prevalence of the various types of maxillary frenal attachments and its morphology in children in Chennai.

Materials and methods

A study involving 931 Children between 3 and 12 years of age attending schools in Chennai were clinically examined for maxillary labial frenal attachment location and morphology under direct visual method. Parents were provided with informed consent. Demographic details including age and sex were recorded.

Results

Total number of children who were examined were 931. The most prevalent type of frenal attachment among all is gingival type followed by mucosal type of attachment. 49.5% were gingival type, 38.8% were mucosal type, 9.8% were papillary type and 1.9% were papillary penetrating type. The prevalence type had no gender difference but the age had significant association. The occurrence of papillary penetrating type decreases with age. The most prevalent morphological type is simple frenum 97% followed by simple frenum with nodule which is 2.6% and bifid labial frenum which is 0.4%.

Conclusion

The prevalent type among Chennai children is gingival type. The papillary penetrating type of frenal attachment decreases with age. The dentists should correlate the age of the child and type of frenal attachment and morphological variations during their clinical examination to avoid misdiagnosis and unnecessary treatment.

How to cite this article

Christabel SL, Gurunathan D. Prevalence of Type of Frenal Attachment and Morphology of Frenum in Children, Chennai, Tamil Nadu. World J Dent 2015;6(4):203-207.
Root Canal Irrigants in Primary Teeth
Authors: Vora Miloni S , Nihal Nidhi K , Ramachandra Jaya Agali
Published: March 2016

The endodontic triad consists of cleaning and shaping, disinfection and obturation. Success of root canal therapy in primary teeth is mainly achieved by thorough removal of debris and necrotic tissue. However, complete elimination of bacterial contaminants as well as necrotic debris require adjunctive use of root canal irrigants along with mechanical instrumentation. As we know from literature that none of the available irrigating solutions alone provides all the ideal requirements. Studies have shown that a combination of two or more irrigating solutions in a specific sequence will help to achieve optimal irrigation. This review article mainly highlights the mechanism of action, safety and biocompatibility of currently used irrigation solutions and also the other materials that can be used as a potent irrigants, their advantages and limitations in future of endodontics.

How to cite this article

Ramachandra JA, Nihal NK, Nagarathna C, Vora MS. Root Canal Irrigants in Primary Teeth. World J Dent 2015;6(3):229-234.
Sterile Feminine Hygiene Sanitary Napkin Dressing in the Management of Ludwig's Angina
Authors: Waknis Pushkar , Prasad GSV , Limaye Gandhali
Published: March 2016

Dry environment plays a very important role in the healing of infections. Commercially available sanitary pads were sterilized individually using ethylene trioxide (ETO) for 24 hours and used as dressing material in 10 Ludwig's angina patients. When compared with conventional gauze dressing, it showed significantly less number of dressing changes. We recommend its use as an alternative absorbent wound material for head and neck infections.

How to cite this article

Waknis P, Sarode SC, Prasad GSV, Limaye G, Sarode GS. Sterile Feminine Hygiene Sanitary Napkin Dressing in the Management of Ludwig's Angina. World J Dent 2015;6(4):239-240.
True Pulp Stones in Compound Odontome: An Unusual Finding
Authors: Anand Rahul , Waknis Pushkar
Published: March 2016

Calcifications within dental pulp are not a rare phenomenon. Rarely, they can be seen in association with dentin dysplasia type II, pulpal dysplasia, tumoral calcinosis, Ehlers-Danlos syndrome type I, Saethre-Chotzen syndrome, Elfin-Facies syndrome, familial expansile osteolysis, osteogenesis imperfecta type I and otodental syndrome. We came across a case of compound odontome in the maxillary posterior region with multiple true pulp stone formation at the microscopic level. Such an unusual association has not been reported in the English medical literature till date.

How to cite this article

Sarode GS, Sarode SC, Anand R, Waknis P. True Pulp Stones in Compound Odontome: An Unusual Finding. World J Dent 2015;6(4):241-242.
Re-anatomization of Conoid and Deciduous Lateral Incisors with Direct Composite Resin
Authors: Santezi Carolina , de Andrade Marcelo Ferrarezi , Bortolatto Janaína Freitas , Floros Michael Christopher , Dovigo Lívia Nordi
Published: March 2016

Discrepancies in tooth size and shape are commonly encountered in the dental clinic, and the conoids lateral incisors are among the most affected. This anomaly affects approximately 1% of the population and it strongly influences the disharmonic characteristics in the smile. This paper reports a clinical case describing a correct diagnosis, planning and the subsequent esthetic treatment of asymmetric lateral incisors using direct composite resin.

How to cite this article

Santezi C, Bortolatto JF, Floros MC, de Andrade MF, Dovigo LN. Reanatomization of Conoid and Deciduous Lateral Incisors with Direct Composite Resin. World J Dent 2016;7(1):4146.
Chronology and impact of the 2011 Cordón Caulle eruption, Chile
Authors: Elissondo Manuela , Baumann Valérie , Bonadonna Costanza , Pistolesi Marco , Cioni Raffaello , Bertagnini Antonella , Biass Sébastien , Herrero Juan-Carlos , Gonzalez Rafael
Published: March 2016

Abstract. We present a detailed chronological reconstruction of the 2011 eruption of the Cordón Caulle volcano (Chile) based on information derived from newspapers, scientific reports and satellite images. Chronology of associated volcanic processes and their local and regional effects (i.e. precursory activity, tephra fallout, lahars, pyroclastic density currents, lava flows) are also presented. The eruption had a severe impact on the ecosystem and on various economic sectors, including aviation, tourism, agriculture and fishing industry. Urban areas and critical infrastructures, such as airports, hospitals and roads, were also impacted. The concentration of PM10 (particulate matter  ≤  10 µm) was measured during and after the eruption, showing that maximum safety threshold levels of daily and annual exposures were surpassed in several occasions. Probabilistic analyses suggest that this combination of atmospheric and eruptive conditions has a probability of occurrence of about 1 %. The management of the crisis, including evacuation of people, is discussed, as well as the comparison with the impact associated with other recent eruptions located in similar areas and having similar characteristics (i.e. Quizapu, Hudson and Chaitén volcanoes). This comparison shows that the regions downwind and very close to the erupting volcanoes suffered very similar problems, without a clear relation to the intensity of the eruption (e.g. health problems, damage to vegetation, death of animals, roof collapse, air traffic disruptions, road closure, lahars and flooding). This suggests that a detailed collection of impact data can be largely beneficial for the development of plans for the management of an eruptive crisis and the mitigation of associated risk of the Andean region.
Rapid glacial retreat on the Kamchatka Peninsula during the early 21st Century
Authors: Lynch Colleen M. , Barr Iestyn D. , Mullan Donal , Ruffell Alastair
Published: March 2016

Abstract. Monitoring glacier fluctuations provides insights into changing glacial environments and recent climate change. The availability of satellite imagery offers the opportunity to view these changes for remote and inaccessible regions, often underrepresented in glacial inventories. Gaining an understanding of the ongoing changes in such regions is vital if a complete picture of glacial fluctuations globally is to be established. With this in mind, here we use satellite imagery (Landsat 7, 8 and ASTER) to conduct a multi-annual remote sensing survey of glacier fluctuations on the Kamchatka Peninsula (Eastern Russia) over the 2000–2014 period. Glacier margins were digitised manually, and reveal that in 2000, the peninsula was occupied by 676 glaciers, with a total exposed-ice area of 664.8 ± 23.9 km2. By 2014, the number of glaciers had increased to 766 (reflecting the fragmentation of larger glaciers), but their surface area had decreased to 465.1 ± 15.7 km2. This represents a ~ 30 % decline in total glacier surface area between 2000 and 2014, and a notable acceleration in the rate of area-loss since the late 20th century. Analysis of possible controls indicates that these glacier fluctuations were likely governed by variations in climate (particularly rising summer temperatures), though the response of individual glaciers was modulated by other (non-climatic) factors, principally glacier size and local shading.
Percepção de mães sobre um manual educativo sobre estimulação visual da criança
Authors: Silva Grazielle Roberta Freitas da , Cardoso Maria Vera Lúcia Moreira Leitão
Published: March 2016

A falta de conhecimento por parte das mães acerca da saúde ocular dos seus filhos é um denominador comum encontrado quando são abordadas sobre essa temática, principalmente relacionado à estimulação visual(EV), componente de valor significativo na saúde ocular dos recém-nascidos. Objetivamos investigar a percepção de mães de crianças com riscos para alterações visuais quanto ao conteúdo e aplicação de um manual sobre EV. O manual foi entregue às mães na enfermaria mãe-canguru juntamente com os materiais para EV, de abril a junho de 2005, em Fortaleza-CE, no qual elas leram sob a supervisão da pesquisadora. No 5º dia ou na alta eram realizadas entrevistas individuais gravadas sobre sua percepção quanto ao método de educação em saúde a 12 mães. Os dados foram organizados em quatro temas, a saber: Percepção do manual, Conhecimento das mães acerca da saúde ocular, Estrutura do manual e Promoção à saúde ocular. Concluímos que o manual facilitou a aprendizagem sobre a EV, como também facilitará a identificação de alterações visuais durante a convivência familiar, além de proporcionar incentivo à continuidade da estimulação no domicílio como fator indispensável para o desenvolvimento da criança, seja ela prematura ou não.
Especificação de sistema de informação de microáreas de risco utilizando a abordagem orientada a objetos
Authors: Stein Júnior Altair Von , Malucelli Andreia , Bastos Laudelino Cordeiro
Published: March 2016

O programa de saúde da família é uma estratégia que norteia a assistência à saúde por meio de ações assistenciais, educacionais, de promoção e prevenção aos agravos à saúde. Como método de trabalho as equipes realizam o reconhecimento da comunidade buscando identificar áreas de maior risco à saúde para planejarem ações.  Para isso são obtidos dados de diversos sistemas de informação, entretanto, esses sistemas nem sempre permitem a aquisição de dados atualizados ou referentes às condições de áreas específicas. Assim, o objetivo deste estudo é apresentar a especificação de um sistema de informação referente às condições ambientais e de infra-estrutura contidas na microárea contribuindo para o armazenamento e recuperação de informações de maneira atualizada e específica. Trata-se de uma pesquisa de desenvolvimento realizada em Curitiba de Janeiro a Junho/2007, onde foi realizado brainstorm para definir os requisitos do sistema e a linguagem de modelagem unificada (UML) para a sua especificação. Como resultados foram obtidos os diagramas de casos de uso, diagramas de sequência e diagrama de classes. A implantação de um sistema com as características propostas neste estudo pode agilizar o processo de planejamento local e auxiliar na análise da relação entre ambiente e saúde, com dados atualizados.
Práticas educativas em saúde do enfermeiro com a família da criança hospitalizada
Authors: Góes Fernanda Garcia Bezerra , La Cava Angela Maria
Published: March 2016

As reflexões de como os enfermeiros estão realizando as ações educativas em saúde na assistência infantil levaram a questão norteadora deste estudo: Como o enfermeiro tem desenvolvido as ações de educação em saúde com a família da criança hospitalizada? O presente trabalho teve como objetivo caracterizar as práticas educativas em saúde do enfermeiro com a família da criança hospitalizada. Trata-se de um estudo descritivo, exploratório, de abordagem qualitativa, cujos sujeitos foram nove enfermeiros que trabalham na unidade de pacientes internos de um hospital universitário pediátrico localizado no município do Rio de Janeiro. O instrumento para produção dos dados foi a entrevista semi-estruturada, aplicada aos sujeitos entre os meses de setembro a novembro de 2006. A partir da Análise Temática dos dados, emergiu a seguinte categoria: Práticas educativas em saúde: preparando as famílias de crianças dependentes de tecnologia para o cuidado domiciliar. Verificou-se que as ações educativas encontram-se voltadas principalmente para as crianças dependentes de tecnologia. Recomenda-se a criação de serviços de atenção domiciliar para as crianças que necessitam de cuidados especializados de forma tal que suas famílias tenham uma rede de apoio para cuidar de seus filhos e a criação de grupos educativos com as famílias das crianças hospitalizadas.
A experiência em família de uma pessoa com diabetes mellitus e em tratamento por hemodiálise
Authors: Mattos Magda de , Maruyama Sônia Ayako Tao
Published: March 2016

A experiência de adoecimento incorpora processos biológicos, mas também processos subjetivos, que devem ser abordados nas práticas de atenção em saúde. No entanto, revelar os processos subjetivos da experiência tem sido um desafio aos profissionais de saúde. A antropologia interpretativa tem subsídiado a compreensão deste processo na medida que integra aspectos socioculturais ao adoecimento. Estudo de natureza qualitativa, tipo Estudo de Caso teve por objetivo compreender a experiência em família de uma pessoa com diabetes mellitus, insuficiência renal crônica em tratamento por hemodiálise. O estudo foi realizado com um usuário em hemodiálise, em uma clínica no Estado de Mato Grosso e com sua esposa, no período de fevereiro a julho de 2008, por meio da entrevista. A análise dos dados nos permitiu apreender que vivenciar o adoecimento é uma experiência no qual os significados são reconstruídos e vividos com base nas experiências anteriores e nas perspectivas de vida, tendo a família como referência. Aspectos importantes do adoecimento marcaram a experiência de Moisés e sua esposa como o significado atribuído a família nuclear, a fragmentação da estrutura social, as limitações e restrições, o reflexo da doença na vida em família, os comportamentos, a construção da subjetividade masculina e o transplante renal.
Vivência de mulheres que se submeteram à gastroplastia
Authors: Agra Glenda , Henriques Maria Emília Romero de Miranda
Published: March 2016

A gastroplastia reduz as co-morbidades e melhora a qualidade de vida, resgatando a auto-estima e inclusão social do obeso mórbido. O estudo teve como objetivo investigar a vivência de mulheres que se submeteram à gastroplastia, a partir de seus discursos. Trata-se de um estudo exploratório com abordagem qualitativa, do qual participaram 16 pacientes mulheres que se submeteram à cirurgia bariátrica. Os dados foram coletados nos meses de junho a julho de 2007, por meio da técnica de entrevista semi-estruturada, com a utilização do sistema de gravação, as quais foram analisadas qualitativamente, à luz da técnica do Discurso do Sujeito Coletivo. Emergiram as seguintes idéias centrais: elevação da auto-estima e bem-estar psicológico; promoção de bem-estar físico; mudança negativa no pós-operatório imediato e mediato; mudança positiva após a fase de adaptação; possibilidade de maior socialização; satisfação familiar e pessoal enquanto mulher e maior disposição, segurança e melhor estado de humor. Conclui-se, portanto, que, a gastroplastia é um tratamento cirúrgico para obesos mórbidos, que remete à perda ponderal, melhora a auto-estima, mas que traz conseqüências negativas. Daí a importância do cuidar destas pacientes desde a decisão de se submeter à cirurgia até a total reabilitação.
Construção de um banco de termos da linguagem especial de enfermagem
Authors: Tannure Meire Chucre , Chianca Tânia Couto Machado , Garcia Telma Ribeiro
Published: March 2016

Este artigo apresenta a metodologia empregada na construção de um banco de termos da linguagem especial de Enfermagem descrevendo o processo de extração e padronização de termos identificados em prontuários de pacientes internados em uma unidade de tratamento intensivo de adultos, mapeando os termos extraídos com os termos existentes na CIPE® - versão 1.0 e classificando os termos não constantes nos sete eixos dessa classificação. É possível identificar termos que são utilizados na prática por enfermeiros e construir bancos de termos que possam alimentar sistemas de informação que auxiliem na operacionalização das etapas do processo de Enfermagem e na construção de catálogos CIPE®.
Distúrbios osteomusculares relacionados ao trabalho em profissionais de enfermagem de um hospital universitário
Authors: Freitas João Renan Silva de , Lunardi Filho Wilson Danilo , Lunardi Valéria Lerch , Freitas Kênia da Silva Santos de
Published: March 2016

Os Distúrbios Osteomusculares Relacionados ao Trabalho (DORT) representam o principal grupo de agravos à saúde, entre as doenças ocupacionais em nosso país. Esta é uma pesquisa qualitativa, cujos dados foram coletados, por meio de questionário com perguntas abertas e fechadas e de exames físicos e complementares, junto a trabalhadores de enfermagem de um Hospital Universitário. Teve como objetivos: verificar a ocorrência de DORT entre os membros da equipe de enfermagem; identificar os sintomas de DORT mais frequentes entre esses profissionais; identificar as regiões do corpo que mais freqüentemente são afetadas; verificar o número de dias não trabalhados em decorrência dos DORT, no período de janeiro de 2005 a outubro de 2006; identificar as características (sexo, categoria profissional e setor de trabalho) dos adoecidos. Dos vinte e um trabalhadores com queixas osteomusculares, no período de 1º de janeiro de 2005 a outubro de 2006, identificados com base em dados fornecidos pela chefia do Serviço de Enfermagem, quinze aceitaram participar da pesquisa e seis não participaram, sem apresentar os motivos. Os resultados evidenciaram que auxiliar de enfermagem e técnico de enfermagem foram as categorias acometidas por DORT, sendo todos do sexo feminino, oito auxiliares de enfermagem e sete técnicas de enfermagem.
A relação de ajuda não-diretiva junto ao cuidador de um idoso incapacitado
Authors: Ramos Tatiane Mitleton Borges , Pedrão Luiz Jorge , Furegato Antonia Regina Ferreira
Published: March 2016

O Brasil está na posição de um país estruturalmente envelhecido frente ao aumento da expectativa de vida de sua população. No ano de 2007, mais de 7% da população tinha idade de 60 anos ou mais, devido à melhoria na qualidade de vida e a diminuição da taxa de natalidade. O objetivo desse estudo foi analisar a interação de um profissional com um cuidador de uma pessoa idosa, com base na teoria da relação de ajuda não-diretiva. Para isso, foi gravado o processo interativo entre o profissional e o participante, posteriormente transcrito na íntegra, literalmente, e analisado conforme as teorias da relação de ajuda não-diretiva e da relação interpessoal em enfermagem. Os resultados mostraram que o processo interativo estabelecido proporcionou, ao participante, um momento de reflexão sobre a sua vivência na função que assumiu de cuidador, e, mostrou também, os benefícios trazidos pela relação de ajuda não-diretiva na medida em que possibilitou, ao participante, uma maior compreensão e consciência do momento em que vive, trazendo a ampliação da congruência entre seus sentimentos e pensamentos. Mostrou, finalmente, a contribuição que a relação de ajuda não-diretiva pode ter nas propostas de acolhimento das novas diretrizes do Sistema Único de Saúde.
Deep Sclerectomy in Primary Open-Angle Glaucoma and Exfoliative Glaucoma
Authors: Suominen Sakari M.A. , Harju Mika P. , Vesti Eija T.
Published: March 2016

Purpose

To study the effect of deep sclerectomy (DS) in primary open-angle glaucoma (POAG) and exfoliative glaucoma (EXG).

Methods

We retrospectively analyzed the intraocular pressure (IOP)-lowering effect of DS in 235 consecutive eyes. Eyes were divided into 2 groups according to glaucoma subtype: POAG (127 eyes) and EXG (108 eyes). Postoperative IOP was the main outcome measurement. We recorded complete and qualified surgical success, need for YAG-laser goniopuncture, and need for postoperative glaucoma medication. We studied factors related to outcome of surgery in a Cox regression model.

Results

In the POAG group, the mean (SD) IOP decreased from 22.6 (5.1) mm Hg preoperatively to 16.8 (7.5) mm Hg, with qualified success achieved in 70% of eyes. Postoperatively, 57% were without medication. In the EXG group, IOP decreased from 25.5 (6.5) mm Hg preoperatively to 16.5 (7.8) mm Hg postoperatively, with qualified success achieved in 66% of eyes. Postoperatively, 50% were without medication. Decrease in IOP was statistically significant in both groups (p<0.001). In the POAG group, 12%, and in the EXG group, 24% needed a reoperation in the follow-up period (p = 0.037). In the Cox regression model, 1 week IOP between 2 and 14 mm Hg without medication lowered the hazard rate of losing complete success by 34% (p = 0.031) and the hazard rate of losing qualified success by 54% (p = 0.004).

Conclusions

The IOP 1 week postoperatively seems to be a prominent indicator of surgical success. Deep sclerectomy is effective in reducing IOP in POAG and EXG subgroups, with reoperations more common in EXG eyes.
Risk Factors for Visual Impairment in Patients with Sickle Cell Disease in London
Authors: Saidkasimova Shohista , Shalchi Zaid , Mahroo Omar A. , Shunmugam Manoharan , Laidlaw D. Alistair H. , Williamson Tom H. , Howard Joanna , Mohamed Moin D.
Published: March 2016

Purpose

Dramatically improved health care in recent years has increased the life expectancy of patients with sickle cell disease (SCD) as well as the prognosis for its ocular complications. We sought to identify risk factors for visual impairment in patients with SCD in London 4 decades after Goldberg's seminal studies.

Methods

Patients 16 years and older with SCD (genotypes HbSS, HbSC, HbSβ-thalassemia) attending hematology and ophthalmology services were offered ocular examination. Retinopathy was graded according to the Goldberg classification. Visual impairment was defined as corrected distance visual acuity of 20/40 or poorer.

Results

In total, 182 eyes of 182 patients (mean ± SD age, 37.2 ± 12.8 years; female, 65.9%) were included. Women were significantly older than men (mean ± SD age, 38.8 ± 13.1 vs 34.2 ± 11.8 years; p = 0.0174). There was no difference in mean age of each genotype group (p>0.15). Risk factors for sight-threatening proliferative sickle retinopathy (PSR) were age over 35 years (odds ratio [OR] 2.01; 95% confidence interval [CI] 1.05-3.89; p = 0.0359) and HbSC genotype (OR 4.06; 95% CI 2.07-7.98; p<0.0001). Although visual impairment was related to the presence of sight-threatening PSR (OR 7.23; 95% CI 1.50-35.0; p = 0.0138), it was not related to hemoglobin genotype (p>0.50).

Conclusions

We present the largest study of ocular findings in SCD in the United Kingdom. Sight-threatening PSR is a risk factor for visual impairment, but hemoglobin genotype status is not.
Efficacy and Safety of Postvitrectomy Intravitreal Triamcinolone Therapy for Diabetic Macular Edema
Authors: Costa José F. , Sousa Keissy , Marques João P. , Marques Marco , Cachulo Maria Luz , Silva Rufino , Gomes Nuno , Figueira João
Published: March 2016

Purpose

After vitrectomy, diffusion and clearance rates of numerous drugs are increased, leading to a shorter intravitreal half-life. This raises doubts about the efficacy of intravitreal therapies, as retina specialists generally believe that a shorter half-life compromises the drugs’ therapeutic effect. We conducted a study to evaluate the functional and anatomical effect of intravitreal triamcinolone acetonide therapy (IVTA) in previously vitrectomized eyes with diabetic macular edema (DME).

Methods

In this retrospective, multicenter case series study including vitrectomized patients with DME who underwent IVTA injections, central macular thickness (CMT) measured with spectral-domain optical coherence tomography and best-corrected visual acuity (BCVA) in Early Treatment Diabetic Retinopathy Study letters were evaluated after each procedure. All relevant medical data were collected, including previous ophthalmologic treatments and comorbidities.

Results

Twenty vitrectomized eyes of 20 patients, mean age 58.1 years (range 40-72 years), were enrolled in the study. All patients presented DME and received at least one IVTA injection. Mean time between pars plana vitrectomy and IVTA was 12.9 ± 8.7 months. Mean pretreatment and posttreatment CMT was 438.8 ± 90.8 μm and 301.2 ± 76.2 μm, respectively, a difference that reached statistical significance (p<0.001). Mean gain in BCVA letter score was 7.83 ± 14.9 letters after treatment (p = 0.039). Mean intraocular pressure was significantly increased after IVTA (17.2 ± 1.9 mm Hg at baseline vs 21.2 ± 4.59 mm Hg after IVTA, p = 0.002).

Conclusions

A positive anatomical and functional effect was observed in our cohort. Our results suggest that, despite prior vitrectomy, triamcinolone remains a valid therapeutic approach for eyes with persistent DME. Further prospective randomized studies with larger patient samples are needed to validate this conclusion.
Expectation and Quality of Life after Aortic Valve Replacement over 85 Years of Age Match those of the Contemporary General Population
Authors: Salsano Antonio , Regesta Tommaso , Viganò Gaia , Rapetto Filippo , Boeddu Serena , Sportelli Elena , Pansini Stefano , Risso Paolo , Onorati Francesco , Passerone Giancarlo , Santini Francesco
Published: March 2016

Background

In the transcatheter aortic valve implantation (TAVI) years, very elderly patients with aortic stenosis (AS) are referred to surgery with reluctance despite excellent hospital outcomes. A poorly assessed outcome of discharged survivors might further overlook the actual efficacy of the surgical strategy in this cohort. We thus evaluated life-expectancy and functional results in discharged survivors over 85 years operated on for AS.

Methods

Between January 2001 and December 2013, 57 consecutive patients aged ≥85 years underwent aortic valve replacement (AVR) with or without concomitant procedures at our institution. Late survival rate (SR), New York Heart Associaion (NYHA) functional class and quality of life (RAND SF-36) were assessed. SR and quality of life (QoL) were than compared to the contemporary general population matched for age and gender, as calculated by the Italian National Institute of Statistics.

Results

Overall in-hospital mortality was 8.8% (5 pts). In patients without concomitant coronary artery bypass grafting (CABG), in-hospital mortality was 2.9%. Survival at 5 and 9 years was 57.7 ± 8.4% and 17.9 ± 11.4%, respectively. No predictors of late mortality including concomitant CABG were identified at Cox analysis. The mean NYHA class for long-term survivors improved from 3.1 to 1.6 (p<0.001). Survivors reported better QoL-scores compared to the age- and gender-matched contemporary general population in 4 RAND SF-36 domains. Life-expectancy resulted comparable to that predicted for the age and gender-matched general population.

Conclusions

Isolated AVR in patients aged ≥85 years can be performed with acceptable risk. Survivors improve in NYHA class and, when compared to age- and gender-matched individuals, show a similar life expectancy and a no lower QoL.
Can Brackets be Bonded with a Composite Resin after Expiration Date?
Authors: Gungor Ahmet Yalcin , Alkis Huseyin , Turkkahraman Hakan
Published: March 2016

Introduction

The aim of the study was to compare shear bond strengths of brackets bonded with a composite resin before and after expiration dates.

Methods

Forty-five freshly extracted premolar teeth were randomly divided into 3 groups of 15. Ormco Mini 2000 (Ormco Corp, Glendora, Calif) bicuspid metal brackets were used in the study. Group I: the brackets were bonded with Blugloo (Ormco Corp, Glendora, Calif) adhesive paste before the expiration date. Groups II and III: the brackets were bonded with same light cure composite resin 1 and 2 years after the expiration date. All of the groups were cured with a LED light. After bonding, the shear bond strengths of the brackets were tested with a universal testing machine. One-way ANOVA with post-hoc Tukey tests were used to compare shear bond strengths of the groups. The chi-square test was used to determine significant differences in the adhesive remnant index (ARI) scores between the groups. Significance for all statistical tests was predetermined at p<0.05.

Results

No statistically significant difference was found in shear bond strengths and ARI scores between three groups (p<0.05). There was a greater frequency of ARI scores of 2 and 3 and 4 in all groups.

Conclusions

Expiration dates do not have a significant effect on the shear bond strength of the composite material. Further studies are needed to investigate in other ways such as cytotoxicity of the composite resins after expiration date.
Evaluating Serum Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor Binding Protein 3 as Markers in Prostate Cancer Diagnosis
Authors: Rainato Giulia , Fabricio Aline S.C. , Zancan Matelda , Peloso Lucia , Dittadi Ruggero , Barichello Mario , Fandella Andrea , Scattoni Vincenzo , Gion Massimo
Published: March 2016

Background

Prostate-specific antigen (PSA) lacks specificity and sensitivity in discriminating prostate cancer (PCa) from benign prostatic hyperplasia (BPH) when the total PSA (tPSA) level is between 4 and 10 ng/mL. It remains to be investigated if additional tumor-associated molecules may improve the PCa diagnostic accuracy. The aim of the present study was to investigate whether serum levels of insulin-like growth factor 1 (IGF1), insulin-like growth factor binding protein 3 (IGFBP3) and their combinations with PSA may enhance the diagnosis of PCa.

Methods

Serum tPSA and free PSA (fPSA) levels were measured using an automated chemiluminescence-based method. IGF1 and IGFBP3 levels were evaluated by radioimmunoassays in a prospectively and consecutively enrolled subset of 149 patients with tPSA ≤10 ng/mL made up of patients with benign prostatic hyperplasia (BPH; n = 113) and PCa (n = 36).

Results

IGF1 and IGFBP3 serum levels did not significantly differ between the PCa and BPH groups. No important correlation was found between the IGF molecules and PSA isoforms in both groups. Statistical analysis of the combination of markers indicated that only the free/total PSA ratio (f/tPSA%) was informative and independent in predicting the presence of PCa, considering that for high values of this percentage (17%) the probability of finding PCa decreased. Receiver operating characteristics areas under the curve (AUC) for IGF1 and IGFBP3 were not informative (AUC ~0.5 in both cases) contrary to the AUC for f/tPSA% (AUC = 0.689, p = 0.0002).

Conclusions

The present study showed that neither IGF1 and IGFBP3 alone nor in combination with PSA enhance the diagnostic performance of PSA in PCa.
Rapportcijfer voor veiligheid in de buurt: bruikbaar voor beleid?
Authors: van der Aa Bart
Published: March 2016

Rapportcijfer voor veiligheid in de buurt: bruikbaar voor beleid?

Nederlandse gemeenten baseren zich veelal op de uitkomsten van de Veiligheidsmonitor (VM) om te weten hoe inwoners de veiligheid in hun woonomgeving waarderen. Ze kijken hierbij onder andere naar het rapportcijfer voor de veiligheid in de eigen buurt. Maar is dit eigenlijk wel een bruikbaar cijfer? In dit artikel nemen we het conceptuele model van Oppelaar en Wittebrood (2006) als uitgangspunt voor het uitvoeren van een regressieanalyse om te achterhalen waardoor het rapportcijfer voor veiligheid in de eigen buurt wordt verklaard. Het rapportcijfer blijkt door vele zaken te worden beïnvloed, aangevoerd door de manier waarop bewoners aankijken tegen de omvang van de criminaliteit in de eigen omgeving, de ervaren overlast en het oordeel over de wijk. Vanwege de vele kenmerken die meespelen, zo beargumenteren we, doen gemeenten er verstandig aan om het rapportcijfer niet te gebruiken.
Bees of the family Halictidae Thomson, 1869 from Dominica, Lesser Antilles (Hymenoptera: Apoidea)
Authors: Gibbs Jason
Published: March 2016

The bees of the family Halictidae Thomson, 1869 from Dominica are reviewed. Seven new species are described and illustrated: Lasioglossum (Dialictus) kalinago sp. nov., L. (D.) dominicense sp. nov., L. (D.) kilpatrickae sp. nov., L. (Habralictellus) roseauense sp. nov., Sphecodes diablotinus sp. nov., S. albifacies sp. nov. and Habralictus antillarus sp. nov. A description and images of the previously unknown female of Microsphecodes dominicanus (Stage, 1972) are provided. In total, eleven species are recognized; eight nest-building species and three kleptoparasites. All halictid species from Dominica are currently known only from the island. A key to halictid bees from Dominica is provided.
Inviting Prospective Teachers to Share Rough Draft Mathematical Thinking
Authors: Thanheiser Eva , Jansen Amanda
Published: March 2016

Engaging prospective elementary teachers (PTs) in participating productively by making their exploratory (rough draft) thinking public during class discussions remains a constant challenge for instructors of mathematics content courses for teachers, in part because of perspectives incoming PTs may hold about interacting in academic settings. In this article, we share the effects of an intervention designed to confront PTs' incoming perspectives. PTs were provided with opportunities to label the level of completeness and correctness of their thinking before they displayed and discussed their written work publicly during a mathematics content course for teachers. Results indicated that labeling their work increased PTs' level of comfort with sharing their thinking and awareness of the value of doing so. PTs also reported that the label served as a reflection tool. The label increased the PTs' productive disposition in terms of comfort level with taking intellectual risks when doing mathematics and reflecting on their work.
Supporting Teacher Noticing of Students' Mathematical Strengths
Authors: Jilk Lisa M.
Published: March 2016

Video cases and video clubs have become popular tools for supporting teacher learning. One concern is that many of the video projects discussed in the research literature may unintentionally continue to perpetuate deficit perspectives about students by focusing more on their gaps in understanding than on the strengths they bring to their learning. This article describes a video club that is part of a multidimensional professional development network that aims to re-culture mathematics classrooms so that all students have challenging and empowering learning experiences. I discuss shifts in teachers' ways of seeing and talking about students' mathematical activity that the video club has made possible, as well as features of the video club that have supported these shifts.
Representações, estímulos e constrangimentos do árbitro de futebol de 11
Authors: Sarmento Hugo Miguel , Marques Adilson , Pereira Antonino
Published: March 2016

O objetivo do estudo foi conhecer as representações, estímulos e constrangimentos de árbitros portugueses de futebol de 11. Através da realização de entrevistas semiestruturadas foram inquiridos 19 árbitros. Os dados foram analisados através da técnica de análise de conteúdo com o software Nvivo 10. A análise dos resultados permitiu concluir que a representação do que é ser árbitro se consubstancia, sobretudo, pelo paixão e prazer pela atividade, sendo também atribuída significativa importância aos valores como a idoneidade, a isenção, responsabilidade, respeito e dignidade. Referiram que um bom árbitro apresenta não só uma boa condição física, mas também uma estrutura psicológica e um “saber estar” que potenciam o seu desempenho. A generalidade dos entrevistados sentia-se estimulada para o exercício desta atividade, referindo o prazer e a possibilidade de progressão na carreira como os principais estímulos. Aqueles que não se sentiam estimulados consideraram que eram mal remunerados e pouco acompanhados e acarinhados pelos responsáveis da arbitragem. Os principais constrangimentos apontados foram os comportamentos agressivos de adeptos, dirigentes e público, as dificuldades de conciliação com a vida familiar e profissional, as dificuldades de progressão na carreira e a injustiça na avaliação do desempenho.