bluuebunny/crossref_metadata_2025 huggingface dataset:
Level of ethical-legal knowledge of medicine graduants: cross-sectional study in the year of 2020
Authors: Carvalho Leandro Duarte de , Soares Luisa Medeiros , Ferreira Fernanda Cambraia
Published: May 2023

Abstract: Introduction: Complaints about medical malpractice are frequent. Therefore, investigating how the medical student formation is made concerning the ethical and legal aspects, can contribute to its improvement. Objective: To evaluate and compare the level of knowledge of medical students from a university about ethical and legal aspects of the profession, based on their formation in the disciplines of the related axis (Medical Ethics and Bioethics; Legal Medicine and Deontology/Medical Forensics and Good Practice). Method: Cross-sectional study carried out through the application of an online questionnaire (August-November/2020) based on the Code of Medical Ethics (CME) and the Code of Ethics for Medical Student- 10 sociodemographic and 12 objective questions (Topics: “Professional Confidentiality”, “Medical student’s Interpersonal Relations”, “Medical Publicity”, “Relations with Patients and Families”, “Human Rights”, “Fundamental Principles”, “Medical Activity” and “Telemedicine”). A total of 116 students were evaluated at the start, middle and end of the medical course. The Kruskal-Wallis and Dunn tests were used for comparisons. The Chi-Square and Fisher’s exact tests were used for the association of categorical variables. Results: The performance increased throughout the course, with statistical significance between the average number of correct answers in the 1st, 6th and 10th/12th periods: 5.1; 6.7 and 7.8, (p-value <0.001). The analysis by thematic blocks, on the other hand, did not show a statistical association of correct answers with progress in the medical course (p-value >0.05) for broad-reaching topics and development of competences from the basic cycle, such as “Medical Publicity”, “Relations with Patients and Families”, “Telemedicine” and “Medical Student’s Interpersonal Relations” - with emphasis on the student’s limitations in providing care. As for topics that required competences inherent to the disciplines of the ethical-legal axis, this association was identified (p-value <0.05), as follows: “Professional Confidentiality”, “Human Rights”, “Fundamental Principles”, “Medical Activity” and “Medical Student’s Interpersonal Relations” - specifically on the use of electronics. Finally, the highest percentage of correct answers (95.7%) is associated with “Medical Student’s Interpersonal Relations”, with an emphasis on the student’s limitations. While the lowest rates were found in “Professional Confidentiality” (18.1%), “Medical Activity” (33.6%) and “Human Rights” (25%)”. Conclusion: There is an association between the medical formation proposed by the ethical-legal axis, and the effective increase of the medical student’s level of knowledge concerning the ethical-legal aspects of the profession.
Pandemia da Covid-19: um evento traumático para estudantes de Ciências Biológicas e da Saúde?
Authors: Ramos Sérgio Ricardo Freire , Braga Filho Rodrigo Araújo , Carvalho Mateus Almeida de , Costa Danilo Duarte , Carvalho Lucas Almeida de , Almeida Maria Tereza Carvalho
Published: May 2023

Resumo: Introdução: Os universitários de Ciências da Saúde se tornaram especialmente afetados pela pandemia do vírus Sars-CoV-2. As angústias intrinsicamente relacionadas à Covid-19 foram somadas aos impactos referentes às mudanças acontecidas nas instituições acadêmicas, particularmente a mudança para o ensino on-line, uma metodologia que pode gerar desconforto aos estudantes, além de vários obstáculos relacionados ao ensino e à aprendizagem, o que pode ter repercussões traumáticas importantes na saúde mental dessa população. Objetivo: Este estudo teve como objetivo verificar a carga mental provocada pela pandemia da Covid-19, como um evento traumático ao ponto de desencadear transtornos psiquiátricos, como o transtorno do estresse pós-traumático (Tept), em universitários. Método: Trata-se de um estudo transversal e quantitativo, com orientação analítico-descritiva, mediante preenchimento de formulário digital anônimo, iniciado após prévia aprovação do Comitê de Ética em Pesquisa. Os sujeitos foram estudantes de Ciências Biológicas e da Saúde de uma universidade estadual localizada na Região Sudeste do Brasil. A amostra foi constituída por 618 estudantes. Resultado: Foram respondidos 618 formulários pelos estudantes que pertenciam aos cursos de Educação Física (28,8%), Medicina (25,4%), Odontologia (18,1%), Ciências Biológicas (15,2%) e Enfermagem (12,5%). A presença de sintomas de estresse pós-traumático verificados pela Escala de Impacto do Evento-Revisada (IES-R) obteve prevalência de 32,7% (n = 202) entre os estudantes universitários das Ciências Biológicas e da Saúde. Conclusão: Houve impacto significativo na saúde mental dos universitários com presença de sintomas depressivos, ansiedade e estresse acima dos encontrados na literatura científica, e, consequentemente, constatou-se alta na prevalência do Tept.
Global Assessment of Pediatric Patient Safety Tool for identifying safety incidents in pediatric patients
Authors: Brandão Marilise Borges , Hermann Ana Paula , Lima Mônica Nunes
Published: May 2023

Abstract Objective: The aim of this study was to evaluate the accuracy of the Global Assessment of Pediatric Patient Safety (GAPPS) in order to identify patient safety incidents with patient harm or adverse events (AEs). Methods: This is a cross-sectional, retrospective study of 240 records of hospitalized patients of both genders under 18 years of age, systematically and randomly selecting 10 charts of patients that meet the GAPPS criteria every 15 days from the 4,041 records of 2017. Results: The prevalence of AEs was 12.5%, i.e., detected in 30 out of 240 medical records. In total, 53 AEs and 63 harm were recorded, of which 53 (84.1%) were temporary and 43 AE (68.2%) were definitely or probably preventable. The presence of at least one trigger in a medical chart revealed 13 times greater chance of the occurrence of an AE, with sensitivity index of 48.5%, specificity of 100%, and accuracy of 86.5%. Conclusion: GAPPS was effective in detecting patient safety incidents with harm or AE.
Consumption of ultra-processed foods and associated factors in children from Barbacena (MG), Brazil
Authors: Fonseca Marlene de Melo , Coimbra Rafaela Vitoria Guilherme , Oliveira Julia Silva e , Soares Anne Danieli Nascimento , Gomes Júnia Maria Geraldo
Published: May 2023

Abstract Objective: To evaluate the prevalence of ultra-processed food consumption and associated factors among children enrolled in the public school system of the city of Barbacena, Minas Gerais, Brazil. Methods: This is a cross-sectional study conducted with schoolchildren aged 7–9 years, of both sexes, enrolled in state public schools. Food intake was assessed using the Previous Day Food Questionnaire and the level of physical activity by the Previous Day Physical Activity Questionnaire. The listed foods were classified according to the extent and purpose of industrial processing, using the NOVA classification. Pearson’s χ2 test, Fisher’s exact test, χ2 with Yates correction, and Poisson regression were used in the statistical analysis, estimating the crude and adjusted prevalence ratio, with 95% confidence intervals. Results: The prevalence of daily ultra-processed food consumption was 69.6%. After adjusted analyses, the consumption of ultra-processed food was associated with the omission of breakfast, mid-afternoon snack, supper, low physical activity, and consumption of risk foods. On the other hand, consumption of in natura or minimally processed foods was associated with older age, the consumption of lunch, mid-afternoon snack, dinner, and protective foods. Conclusions: There is a high prevalence of ultra-processed foods consumption, associated with unhealthy dietary habits among schoolchildren. This highlights the need for nutritional counseling and educational actions, favoring healthy eating in childhood.
(Des)conhecimento do diabetes nas escolas: percepção de crianças e adolescentes
Authors: Mourão Denise Machado , Melgaço Natália Mota , Frias Nathália Felícia Silva , Silva Nayara Benedito Martins da , Silva Roberta Scaramussa da , Sedlmaier Bruna Martins Grassi , Borges Grasiely Faccin
Published: May 2023

Resumo Objetivo: Verificar a percepção sobre o diabetes dos alunos de escolas públicas. Métodos: Estudo descritivo transversal, com entrevista aos alunos sobre diabetes (sinais e sintomas, alimentação e questões sobre o autocuidado no ambiente escolar), com análise de conteúdo para a questão aberta, expressa em número de ocorrências, e demais resultados em frequência, média e desvio padrão. Resultados: 302 estudantes, com 9,1±1,5 anos e 54% do sexo feminino. Termos associados a consequências negativas tiveram 91 ocorrências para “o que é diabetes”. Para 95,4% dos entrevistados a pessoa com diabetes não pode comer doces, e para 32,8% o diabetes é transmitido de uma pessoa para outra. Apenas 34,8% afirmaram que o colega com diabetes pode participar de atividades físicas/recreativas, e 32,1% responderam que ele não poderia lanchar junto com os demais. Somente 29,2% dos entrevistados reconheceram que o colega com diabetes precisaria ter consigo algo com açúcar para momentos em que se sinta mal. Conclusões: Estes achados reforçam a necessidade de melhorar o conhecimento e a percepção dos estudantes sobre o diabetes no ambiente escolar, propiciando condições mais harmoniosas e seguras de manejo do diabetes nestes espaços.
Situational analysis of a Speech, Hearing and Language clinical school at a federal university in Bahia: a focus on problems
Authors: Andrade Natalia Vital de Sales , Matos Catharina
Published: May 2023

Abstract This work describes a situational analysis of a Speech, Hearing and Language clinical school at a federal university in Bahia, examining how it functions and coordinates with the municipal health system in Salvador, Bahia. It is a descriptive case study, whose methodological strategy is based on Carlos Matus’ Situational Strategic Planning (Planejamento Estratégico Situacional: PES) with a Focus on Problems. Our methodological strategy employed document analysis, participant observation, semi-structured interviews and a focus group with institutional actors. The results indicate weaknesses in four of the five categories of analysis, which were: infrastructure, funding, organization, and management. These have led to failings in student training and in the institution’s integration with the municipal health system. Of the twenty identified problems, ten related to the institutional actors’ capacity for both governance and governability, in other words, problems that are amenable to intervention. We conclude that the clinical school must institutionalize the practice of situational strategic planning to combat improvisational practices and enable it to effectively fulfil its two important functions: teaching and healthcare.
Análise da Política de Atenção Integral à Pessoa com Deficiência em uma capital da Região Nordeste do Brasil
Authors: Martins Cybelle Fernanda , Albuquerque Maria do Socorro Veloso de , Oliveira Raquel Santos de , Miranda Gabriella Morais Duarte
Published: May 2023

Resumo Na cidade do Recife, a primeira formulação de uma política de saúde direcionada às pessoas com deficiência (PCD) ocorreu 14 anos após a publicação da Política Nacional. Nesse sentido, o artigo analisou o processo de formulação da Política Municipal de Atenção Integrada à Saúde da Pessoa com Deficiência da cidade do Recife em 2016. Por meio de um estudo de caso, foram estudados o contexto, atores, conteúdo e processo de formulação da política através da realização de análise documental e entrevistas com gestores, representantes do Conselho de Saúde e de entidades representativas da PCD. A Política estudada foi formulada em um macrocontexto de vulnerabilidade social acentuado pelo golpe de 2015 e por medidas severas de austeridade fiscal que têm impactado desproporcionalmente as PCD. No microcontexto, percebeu-se influência da área de Direitos Humanos, das eleições municipais e da epidemia da síndrome congênita pelo Zika vírus, que descortinou um vazio assistencial. Houve incipiente participação das PCD, que desconhecem seu conteúdo e pouco acompanham sua implementação. A participação social é fundamental para atender às necessidades das PCD, por isso, pode-se afirmar que é imperativo o estabelecimento de uma relação dialógica em torno da Política e dos desafios de sua implementação.
O debate nas Ciências do Trabalho: do que estamos falando?
Authors: Rocha Raoni
Published: May 2023

Resumo O debate sobre o trabalho tem ocupado, nos últimos anos, um espaço importante nas abordagens das Ciências do Trabalho, principalmente naquelas desenvolvidas pelo CNAM-Paris (Conservatoire National des Arts et Métiers) ou inspiradas por essa escola. Disciplinas como a Ergonomia, a Psicodinâmica do Trabalho ou a Clínica da Atividade têm apresentado métodos que desenvolvem o debate do e no trabalho, de maneira a compreender a atividade realizada, bem como contribuir com transformações das situações de trabalho. Apesar disso, a literatura é relativamente escassa no que concerne às particularidades do debate em cada uma dessas disciplinas e de seus métodos. Com isso, o objetivo deste ensaio é buscar compreender o que compõe o debate nas abordagens das Ciências do Trabalho e também qual o seu potencial, identificando as particularidades inerentes a cada uma delas. É possível notar que existem semelhanças - como a centralidade analítica das contradições no debate - mas também muitas singularidades entre as disciplinas e seus métodos, tais como o funcionamento dos espaços em que o debate ocorre e a maneira com a qual ele é capaz de analisar a atividade e transformar o trabalho. Por fim, defendemos a necessidade de incorporação das especificidades do debate nas pesquisas sobre o tema, evitando assim cacofonias sobre o assunto.
Knowledge of professional contexts in the development of prospective teachers’ educators
Authors: Almeida William Xavier de , Richit Adriana
Published: May 2023

ABSTRACT The article addresses the professional knowledge developed by prospective teachers’ educators from the formative courses offered by the institutions where they work. This qualitative-interpretative work was based on Lee Shulman's professional knowledge perspective. It involved the analysis of official and institutional documents related to policies and formative actions aimed at teacher educators, a questionnaire applied to the faculty in human sciences, and an interview with four university professors selected from those who answered the questionnaire. The research participants teach degree courses in human sciences at a federal university in southern Brazil. As a result, the study points out that the teachers’ participation in different formative sessions allowed them to develop knowledge about multiple aspects related to the knowledge of professional contexts of higher education teaching, with emphasis on students’ and faculty's contexts and institutional and regional social contexts.
Education for power or the art of good meetings three or four ideas about Espinosa and education
Authors: Barreto André Valente de Barros , Pelbart Peter Pal
Published: May 2023

ABSTRACT Starting from some of the ideas present in Ethics, such as desire as a human essence, the theory of affections and the psychophysical parallelism, we explore some possible relationships between Espinosa’s philosophy and education, with the aim of making the teaching-learning process a emancipatory somato-affective experience based on good encounters between bodies-subjects with a view to building an ethical path for both students and teachers.
Assessment of Program Outcomes in Outcome Based Education through Students' Co-Curricular Activities
Authors:   Kongu Engineering College, Erode,TamilNadu India., S J Suji Prasad , M Thangatamilan , R Sureshkumar , P Revathi
Published: May 2023

ABSTRACT (OBE) has become the focal point in the Indian Higher education system. The National accrediting agency, such as NBA and NAAC expresses the significance of assessing the program outcomes. This paper discusses assessing program outcomes through students' cocurricular activities such as paper and project presentations and internships/industrial projects. The proposed method gives an in-view of the rubricsbased measurement of program outcomes PO1-PO12, PSO1&2 mapped with students' co-curricular activities. The outcome-based assessment of program outcomes will be beneficial in advancing higher education in India. Keywords: co-curricular activities; internship; outcome based education; paper and project presentation; program outcomes; rubrics
Learner Autonomy in Team-based Learning: A Case Study of Mechanical Engineering Education
Authors:   Department of Mechanical Engineering, Southern Taiwan University of Science and Technology, Tainan, Taiwan., Lin Yu-Sheng , Lin Yu-Hsuan ,   Department of Economics, the Catholic University of Korea, Bucheon, South Korea.
Published: May 2023

Abstract :Team-based learning (TBL) has been increasingly applied in engineering and science education over the past decade. This study explores a particular TBL approach used in a mechanical engineering module for second-year undergraduates in Taiwan. The results of a survey on these students’ learner autonomy (LA), perceptions of TBL, engagement with TBL, self-reported contributions and concerns about TBL activities were analyzed along with their academic performance. The results suggested that LA played a crucial role in TBL, especially contribution to group work, and that classroom implementations should therefore make it a priority to boost LA. In addition, positive reciprocity was found to be operating during group work. Group differences were found in issues the students expressed concern about. Students who cared about fairness had higher LA and were more likely to contribute to team tasks whilst some students could have been less engaged in group activities due to poororganizational structure. Several challenges were also observed in this study. They included passive learners, classroom-management problems, free-riding, and limited resources. Based on our findings, we recommend that engineering instructors encourage student-teacher communication by using bonus-point incentives, student experts, peer evaluation and group competitions. Keywords : Learner autonomy, mechanical engineering education, Taiwan, Team-based learning.
Enhancement of Program Outcomes for Cryptography and Network Security course using Alternate Assessment Tool: An approach towards outcome-based education
Authors:   Department of Computer Science and Engineering, B.M.S. College of Engineering, Bengaluru-560019, India, M Namratha , S Selva Kumar ,   Department of Computer Science and Engineering, B.M.S. College of Engineering, Bengaluru-560019, India, Sainath Krishnamurthy ,   Department of Chemical Engineering, B.M.S. College of Engineering, Bengaluru-560019, India
Published: May 2023

Abstract: Outcome-based education is being practiced across the globe to enhance the employability of the undergraduates by instilling certain domain-specific skills. Evaluation is key in measuring the leaning outcomes of students. Tools such as regular quizzes, assignments, and alternative assessment are in place for continuous evaluation. Alternative assessment tools (AAT) can be modulated to suit the course being taught, and if used properly, it can enhance the attainment of program outcomes (PO). To enhance the coding skills of the students with respect to security algorithms and their real-time applications, for the course “Cryptography and Network Security”, in the computer science and engineering branch, AAT was introduced in the assessment process. Students were given a task to develop an algorithm using CryptTool and demonstrate the various attacks on the selected encryption/decryption algorithm. By using AAT, engagement of students was improved due to fortnightly reviews from the teacher, peer reviews, and exchange of ideas to go in the right direction in the work plan. The results show improvement in the attainment of program outcomes PO4 and PO5, which were not mapped when AAT was not yet implemented. In addition, the use of CrypTool as part of AAT helped the students in selecting suitable security projects in their higher semester courses. Keywords: Alternate Assessment Tool; Bloom's Taxonomy; CO Attainment; CryptTool; Outcomebased Education; PO Attainment
IMPACT OF STRUCTURAL DEFECTS ON THE RELIABILITY OF POLYMER PIPES REINFORCED WITH METAL BELTS
Authors: Gallyamov V. R. , Romanchuk A. S. , Chervov A. A. , Andriyashkin L. N. , Vinogradov P. V.
Published: May 2023

Reinforced Thermoplastic Pipes (RTP; or Flexible Composite Pipes) are multilayered pipes that consist of inner, outer polymer shell and reinforcement layers. Although there are different types of reinforcement, due to widespread use in oil gathering systems in Russia, we consider steel strip reinforced pipes in this paper. While developing RTP manufacturers state constructive characteristics after conducting analytical analysis and experimental investigations. Final characteristics values are then published in technical regulations documents. Deviation from these values weaken strength of pipeline.As a result of conducted research it was shown that a thinning of a reinforcement strip by 0,1 mm leads to decrease in a burst pressure by 16 %. Similar effect on the pipe reliability has a deviation of the winding angle.
Regulation of Video Gaming Loot Boxes: Lessons for South Africa from Abroad
Authors: Van der Westhuizen Eduard , Carnelley Marita
Published: May 2023

To optimise income, video game developers incorporate microtransactions into their games. One such microtransaction is a loot box. This is a container that a gamer in certain instances can win or purchase to take a chance on the unknown contents in the hope of obtaining an item that may be useful in the progression of the game. In the case of tradable loot boxes, these items won can also be traded or sold for cash either during the game or on a third-party marketplace. Research has shown that loot boxes are potentially harmful to minors and that there is possibly a link between loot boxes and problem gambling. The labelling of the games seems inadequate as it does not always warn gamers and/or parents of the potentially harmful content. It has also been argued that these loot boxes are an example of the convergence between gambling and gaming in that gambling and gambling-like opportunities are becoming more prevalent in video games. Notwithstanding existing research, the industry has not been forthcoming in addressing these problems. There are some exceptions where the developers amended their games after the gaming community reacted negatively to the introduction of loot boxes or when forced to do so by regulations or other third-party service providers. The call for self-regulation by the industry to adopt a set of ethical guidelines to address these concerns has not yielded the desired results. As a result of the lacklustre actions of the industry, some jurisdictions have addressed these problems through regulation. The mechanisms used by these jurisdictions differ, ranging from the banning of loot boxes to a mere acknowledgement of the potential problems without taking any action. Even where (tradable) loot boxes fall within the legal definition of gambling in national legislation, enforcement has been inconsistent as some argue that using gambling regulatory frameworks to protect vulnerable groups is inappropriate. After discussing these debates and global developments, the article concludes with a discussion of the current South African legal situation vis-à-vis loot boxes with specific reference to the constitutional and international law imperatives, the Film and Publications Board classifications, the consumer protection legislation, and the gambling regulatory framework. It finally provides suggestions for legal changes that may be feasible considering the lessons learnt from abroad.
How Kazakhstani Multi-Vector Foreign Policy Works: Voting in UNGA Analysis
Authors:   National Research University Higher School of Economics, Yuneman Roman
Published: May 2023

The concept of multivectorism is the basis of the foreign policy strategy of the Republic of Kazakhstan. Multivectorism is also the framework within which Kazakhstan carries out its foreign policy in international organizations and integrational institutions. However, the implementation of this aspect of its foreign policy within the UN General Assembly has not yet been studied. To examine the concept of multivectorism, the author analyzes Kazakhstan’s voting cohesion with Russia, China, the USA, Turkey, and Germany in the UNGA from 2007-2022. The author also studies Kazakhstan’s behavior in situations where it voted opposite the way these countries voted. This article analyzes, among other things, the voting cohesion of Kazakhstan and the other countries in question on particular topics, such as disarmament, decolonization, human rights, development issues, armed conflicts, etc., as well as Kazakhstan voting patterns on key resolutions relating to armed conflicts involving the Russian Federation. As a result of quantitative and qualitative analysis of more than 1300 resolutions, the author comes to the conclusion that the main “vector” of Kazakhstan’s foreign policy is China. Not Russia, despite Russia formally enjoying the status of Kazakhstan’s declared key ally. Kazakhstan shares the highest voting cohesion with China (to a lesser extent with Russia, Turkey, and Germany, and only minimally with the United States). Moreover, when China and the other countries under examination vote in opposition to one another, Kazakhstan’s votes were more often in accordance with the Chinese position. The author argues that Kazakhstan also avoids explicit support for the Russian Federation in voting on resolutions related to armed conflicts involving Russia. This is further manifested in the Republic of Kazakhstan’s voting on resolutions related to the conflict in Ukraine. However, the reasons for the high level of voting cohesion between China and Kazakhstan in the UNGA require further research.
Shanghai Cooperation Organisation: Reassessment of the Priorities Against the Background of Old Problems and New Challenges. Book Review: «The Shanghai Cooperation Organization: Exploring New Horizons»
Authors:   Ural State Law University (USLU) named after V.F. Yakovlev, Khalafyan Rustam ,   Tyumen State University
Published: May 2023

This review examines the results of the unique international study devoted to the Shanghai Cooperation Organisation (SCO). The project was carried out on the initiative of eminent Russian specialists and covers the period of the SCO’s formation, the search for new areas of cooperation, and promising fields of interaction among the participating countries. The authors (including lawyers and economists) assess the current state of this regional organization and its future, which allows us to form a quite complete understanding of the SCO and the emerging directions of its development. The monograph was produced by a reputable foreign publishing house, reflecting an attention to regionalization that is especially noticeable against the background of the slowing processes of legal regulation at the universal level in recent years. The monograph reveals the reasons for the states within the SCO to unite efforts for realization of their common interests, which are not limited to traditional cooperation in the field of security. The team of authors pays attention to the specifics of the legal systems of the member states and the relations between the countries, as well as the SCO’s successful responses to challenges in the field of labour and migration, energy, environmental protection, transport, and logistics links. Such an approach reflects the conditions of the national legal implementation of international obligations by SCO members. The main features of the Eurasian concept of human rights are formulated, the existence and significance of which is proclaimed. The study provides necessary diagrams, graphs, and tables. General scientific and special methods of cognition were used in this review to show the structure of the monograph, the individual conclusions of the authors, and proposals. The review offers conclusions about the gradual evolution of the SCO, the growth of the humanitarian component of its competence, and the existing contradictions between the potential of the organization and the results achieved.
Current understanding of the cardiotoxicity-related treatment of immune checkpoint inhibitors in breast cancer
Authors: Jiajing Dai
Published: May 2023

Immune Checkpoint Inhibitors (ICIs) as the most important and widely used currently, have changed the traditional approach to cancer treatment and significantly improved the prognosis of most patients with advanced malignancies. Breast cancer is the most dangerous threatening tumor to women’s health and life globally, ICIs have shed light on the treatment for refractory breast cancer subtypes, including Triple-Negative Breast Cancer (TNBC) and trastuzumab resistance of human epidermal growth factor receptor 2 positives (HER2+). However, immune-related adverse events (irAE) associated with ICIs bring many extra considerations. Among these, potential cardiotoxicity is rarely seen but with the highest fatality rate. In the present review, we introduced the ICIs approved for the treatment of breast cancer and brief guideline for clinical application. Then we briefly summarized ICIs-related cardiotoxicity in breast cancer and mechanism based on immunology and basic medical research. Furthermore, we make a brief summary of the diagnosis methods.
Therapeutic applications and effects of Lupinus angustifolius (Blue lupin) and its components. A systematic review with meta-analysis. v1
Authors: Fernández Castillo Rafael
Published: May 2023

Reviews have focused on the blue lupin (Lupinus angustifolius) diet based on the reduction of analytical and anthropometric parameters in pathological populations or, alternatively, without population differentiation. The aim of this study was to investigate the scientific evidence on the biological properties of blue lupin (Lupinus angustifolius), its chemical constituents and their relevance for the treatment of health and disease in humans. The effect of the blue lupin diet was evaluated in conjunction with weight, BMI, blood glucose, LDL cholesterol and triglycerides. Boolean algorithms from various databases (PubMed, Scopus and Web of Science).
Effective Use of Indigenous Microorganism (IMO) in Composting a Mixture of Food and Yard Wastes on an Industrial Scale
Authors:   Civil Engineering Programme, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Malaysia., Kamaruzzaman Farishya , Md Zain Shahrom ,   Smart & Sustainable Township Research Centre (SUTRA),  Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Malaysia, Mat Saad Nur Fatin ,   Civil Engineering Programme, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Malaysia., Basri Hassan ,   Centre for Engineering and Built Environment Education Research (PEKA),  Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Malaysia., Ahmad Basri Noor Ezlin ,   Civil Engineering Programme, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Malaysia.
Published: May 2023

The aim of this research is to determine the performance of effective microorganisms (EM) in the composting of mixed food and yard wastes on an industrial scale. Composting parameters such as temperature, moisture content, pH, and the carbon to nitrogen ratio (C:N), as well as the maturity of nitrogen, phosphorus and potassium (NPK), were determined. For this purpose, the type of EM used to accelerate the composting process is Indigenous Microorganism (IMO). The study, which was conducted using the best EM, accelerated the composting process, wherein it only takes approximately 13 weeks for the decomposition process to occur in each heap. The results show that the final temperature for each heap is between 25.57 and 28.03 ͦ C, the percentage of moisture content is between 45.55 and 60.49%, the pH is between 6.81 and 7:41, the ratio of carbon to nitrogen is between 17:1 and 23:1, the NPK value for nitrogen ammonia is between 0 mg/L and 0.56 mg/L, the potassium content is between 2.25 and 3.25 ppm, and the value of phosphorus is between 0.56 and 0.76 ppm. Based on these results, it can be concluded that the quality of the compost produced for all piles is high. Due to the slight differences in parameters between all piles, the effectiveness of EM IMO was not conclusive for either open or closed aerated piles, and further research needs to be done.
Features of the formation of the Сhristian church in the early Сhristian period
Authors: Kovalenko Andri
Published: May 2023

The article is devoted to the analysis of key aspects of the formation of the Church in the period of early Christianity. The evolution of the meaning of the word "church" from the ancient Greek understanding of it as a popular assembly to the Christian understanding as the Body of Christ is shown. It is proved that the organizational structure of the Church was formed under the influence of historical, social, political and economic factors. It is shown that the early Christian Church was formed in the conditions of fierce external and fierce internal disputes. Already in the period of early Christianity, the Church made a turn from self-isolation to communication with society, and Christian ontological ideas are embodied in various spheres of life – social, political, economic, and so on. An important role was played by the early period of the Church's formation in the anthropological aspect. Christian anthropological ideas formed new meanings of social consciousness, a new type of man, which combines the divine and earthly, eternal and perishable, and whose spirit goes far beyond the horizons of all possible philosophical or ideological ideas. The understanding of man as the image and likeness of God served to affirm human dignity and new moral and ethical guidelines in all spheres of his existence.
AI-Based Literature Reviews: A Topic Modeling Approach
Authors: Verma Manoj Kumar , Yuvaraj Mayank
Published: May 2023

The purpose of this paper is to highlight the importance of topic modelling in conducting literature reviews using the opensource LDAShiny package in the R environment, with green libraries literature as a case study. To conduct the analysis, a title and abstract dataset were prepared using the Scopus database and imported into the LDAShiny package for further analysis. It was found that the green libraries' literature ranged from 1989-2023, with a sharp increase in research topics since 2003. The study also identified key themes and documents associated with green libraries research, revealing that energy efficiency, waste reduction and recycling, and the use of sustainable materials have been extensively discussed in the literature. However, further research is needed on the implementation of these practices in libraries, as well as the impact of the COVID-19 pandemic on green libraries. The findings will be beneficial to researchers interested in using topic modelling for literature reviews.
Evaluasi Kinerja Sub Das Krueng Jreu Kabupaten Aceh Besar
Authors: Purgawa Khairun , Basri Hairul , Syahrul Syahrul
Published: May 2023

Abstrak. Dampak perubahan alih fungsi lahan merupakan kejadian di alam yang perlu dipahami untuk menentukan tindakan yang perlu dilakukan di waktu yang akan datang. Strategi pengelolaan DAS masih membutuhkan suatu inovasi pendekatan hidrologi dan lahan untuk memperbaiki situasi DAS. Penelitian ini bertujuan untuk mengevaluasi kinerja  Sub DAS Krueng Jreu Berdasarkan Permenhut P.61 tahun 2014 tahun tentang Monitoring dan Evaluasi Pengelolaan Daerah Aliran Sungai yang mencakup karakteristik Lahan dan karakteristik hidrologi. Hasil penelitian menunjukan persentase lahan kritis yaitu 2,37% (0,023723 ha), Persentase persentase penutupan vegetasi yaitu 78,61% (18250,64) ha, Indeks Erosi sebesar 0,60, Koefisisien Rejim Aliran (KRA) sebesar 26,62  Koefisien Aliran Tahunan (KAT) didapatkan hasil sebesar 0,056, Muatan Sedimen didapatkan hasil 5,02 ton/ha/tahun, frekuensi banjir adalah 1 kali dalam kurun waktu lima tahun, Indeks Penggunaan Air sebesar 22917,30  m3/thn termasuk dalam kelas sangat baik (0,5). Berdasarkan hasil  skoring 8 Sub kriteria  evaluasi kinerja Sub DAS Krueng Jreu yang meliputi Penggunaan Lahan dan Tata Air maka didapatkan hasil akhir senilai 37,75 dengan katagori sangat baik yang berarti kondisi DAS dalam keadaan sangat baik jika di lihat dari penggunaan lahan dan tata air.Performance Evaluation of Krueng Jreu Sub-watershed, Aceh Besar DistrictAbstract. The impact of changes and land-use changes caused is an event in nature that needs to be understood to determine the actions that need to be taken in the future. The watershed management strategy still requires innovation to improve the watershed situation. This study aims to determine the performance of the Krueng Jreu sub-watershed based on the Regulation of the Minister of Forestry P.61 of 2014 concerning Monitoring and Evaluation of Watersheds which includes hydrological characteristics and characteristics. The results showed that critical land was 2.37% (0.023723 ha), the percentage of vegetation cover percentage was 78.61% (18250.64) ha, the Erosion Index was 0.60, the Flow Regime Coefficient (KRA) was 26.62 The Annual Flow Coefficient (KAT) yields 0.056, Sediment Load yields 5.02 tons/ha/year, the frequency of flooding is 1 time within five years, the Water Use Index is 22917.30 m3/yr included in the very good class. (0.5). Based on the scoring of 8 Sub Criteria for evaluating the performance of the Krueng Jreu Watershed which includes Land Use and Water Management, the final result is 37.75 with a very good category which means the watershed condition is in very good condition when viewed from land use and water management.
Analisa Efektifitas Pemecah Kemiri Di Kabupaten Solok Sumatera Barat
Authors: Putri Renny Eka , Sari Rise Prana , Hasan Ashadi
Published: May 2023

Abstrak. Kemiri adalah tanaman perkebunan yang sangat banyak manfaatnya bagi masyarakat. Daging biji merupakan bagian yang paling banyak manfaatnya. Proses pemecahan kemiri dilakukan secara manual dan dengan menggunakan alat atau mesin. Adapun tujuan penelitian adalah untuk melakukan analisis efektifitas kemiri di kabupaten Solok di Sumatera Barat.  Penelitian dilakukan dengan dua perlakukan yaitu dengan melakukan pembekuan bahan dan menyiram setelah dijemur dan menggunakan metoda pada umumnya. Parameter yang dievaluasi pada penelitian adalah sifat fisik kemiri, kapasitas kerja efektif, rendemen pemecahan, pengukuran kadar air, persentase kerusakan hasil, kecepatan putar alat, tingkat kebisingan alat.  Kemampuan dari alat pemecah kemiri dengan bahan baku dibekukan sebesar 924,35 kg/jam, dengan rendemen sebesar didapat 35%. Persentase Hasil utuh yang paling baik yaitu pada kemiri dengan perlakuan pembekuan dalam freezer sebesar 83%. Hal ini dapat dijadikan acuan oleh petani kemiri dalam mengolah kemiri sebelum dipecah untuk mendapatkan hasil yang maksimal.Analysis of the Effectiveness of Candlenut Crackers in Solok Regency, West Sumatra Abstract. Candlenut is a plantation crop that has many benefits for the community. The flesh of the seed is the most beneficial part. The process of splitting hazelnut is done manually and by using a tool or machine. The research objective is to analyze the effectiveness of candlenut in Solok district, West Sumatra. The research was carried out with two treatments, namely by freezing the material and watering it after drying it and using the general method. Parameters observed in this study were the physical properties of candlenut, adequate working capacity, yield of solution, measurement of moisture content, percentage of yield damage, tool rotation speed, tool noise level. The work capacity obtained in hazelnut which was subjected to freezing treatment was 924.35 kg/hour. The highest yield was obtained from frozen hazelnut by 35%. The best percentage of intact yield was candlenut with freezing treatment in the freezer of 83%.
Hubungan Faktor Predisposisi Dan Penguat Terhadap Tingkat Kepatuhan Pedagang Siap Saji Menerapkan Protokol Kesehatan 7M
Authors: Sari Widyawati Wilanda , Redjeki Endang Sri , Rachmawati Windi Chusnia , Gayatri Rara Warih
Published: May 2023

Abstract: The handling of Covid-19 is carried out by implementing the 7M health protocol which needs to be carried out in public places such as markets where large numbers of people meet for a long duration so as to allow transmission of the Covid-19 virus. Therefore, the purpose of this study is to determine the relationship between predisposing factors (knowledge and attitudes) and reinforcing factors (counseling) on ​​the compliance level of fast food traders in the Sukorejo market applying the 7M health protocol. This research includes quantitative research with a cross sectional approach and uses a sample of traders who sell ready-to-eat food or drinks with a total of 83 respondents. This study uses a questionnaire and analyzed using spearman test. From 83 respondents, 71.1 percent of non-compliant traders were found and the most willing were women (56.6 percent), 26-45 years old (43.4 percent), and high school graduates/equivalent (41 percent). After statistical testing, it can be seen that there is a significant relationship between predisposing factors (knowledge and attitudes) and reinforcing factors (counseling) on ​​the level of merchant compliance with p-value less than 0.005. Research advice is given to market officers, Sukorejo Covid-19 officers and respondents to be more attention for applying the 7M health protocol.

Abstrak: Penaganan kasus Covid-19 dilakukan dengan cara penerapan protokol kesehatan 7M yang perlu dilakukan pada tempat umum seperti pasar dimana tempat bertemunya orang dalam jumlah banyak dengan durasi lama sehingga memungkinkan terjadinya penularan virus Covid-19. Oleh karena itu tujuan dari penelitian yaitu untuk mengetahui hubungan antara faktor predisposisi (pengetahuan dan sikap) dan faktor penguat (penyuluhan) terhadap tingkat kepatuhan pedagang siap saji di pasar Sukorejo menerapkan protokol kesehatan 7M. Penelitian ini termasuk penelitian kuantitatif dengan pendekatan cross sectional dan menggunakan sampel pedagang yang menjual makanan atau minuman siap saji dengan total 83 responden. Penelitian ini menggunakan kuisioner dan dianalisis menggunakan bantuan uji spearman. Dari 83 responden didapatkan pedagang yang tidak patuh 71.1 persen dan yang paling banyak bersedia adalah perempuan (56.6 persen) usia 26-45 tahun (43.4 persen), serta tamatan SMA/sederajat (41 persen). Setelah dilakukan uji statistik dapat diketahui bahwa terdapat hubungan signifikan antara faktor predisposisi (pengetahuan dan sikap) dan faktor penguat (penyuluhan) terhadap tingkat kepatuhan pedagang dengan hasil pvalue kurang dari 0,005. Saran penelitian diberikan pada petugas pasar, petugas Covid-19 wilayah Sukorejo serta responden agar lebih memperhatikan penerapan protokol kesehatan 7M.
Survei Keterampilan Passing Pada Permainan Bola Voli Siswa Kelas VIII di SMP Negeri 1 Bagor Kabupaten Nganjuk
Authors: Herdaphasa Yonansyah , Hariyanto Eko , Winarno M. E. , Tomi Agus
Published: May 2023

Abstract: The occurrence of the COVID-19 pandemic that hit Indonesia in 2020-2021 resulted in activities in all sectors being carried out online, including educational activities. This is also done in one of the PJOK subjects that should be done in the field. Based on the observations made there are 75 percent or 48 students out of 64 students who are less precise in practicing volleyball, this is evidenced by the way of passing, serving, and smashing. So this study aims to determine the basic technical skills of passing in volleyball games for class VIII junior high school students at SMP Negeri 1 Bagor, Nganjuk Regency. The research method used is a survey with a quantitative descriptive approach. The population amounted to 288 with the number of samples based on the Slovin formula, namely 74, consisting of 36 male students and 38 female students. The results of the study showed that the scores of men and women's passing under were in the very poor category with the number of students 22 with a percentage of 61 percent, girls 29 students 76 percent. Passing over sons and daughters falls into the category of very low with the number of students 21 with a percentage of 58 percent, 18 students with a percentage of 47 percent for girls. So it can be said that most of the students in passing boys and girls fall into the very poor category.

Abstrak: Terjadinya pandemi covid-19 yang melanda Indonesia pada tahun 2020-2021 mengakibatkan kegiatan di seluruh sektor dilakukan secara online termasuk kegiatan kependidikan. Hal ini juga dilakukan pada salah satu mata pelajaran PJOK yang seharusnya dilakukan di lapangan. Berdasarkan observasi yang dilakukan terdapat 75 persen atau dengan jumlah 48 siswa dari 64 siswa kurang tepat dalam melakukan praktik bola voli, hal ini dibuktikan dari cara melakukan passing. Sehingga penelitian ini bertujuan untuk mengetahui keterampilan teknik dasar passing pada permainan bola voli siswa SMP kelas VIII di SMP Negeri 1 Bagor Kabupaten Nganjuk. Metode penelitian yang digunakan adalah survei dengan pendekatan deskriptif kuantitatif. Populasi berjumlah 288 dengan jumlah sampel berdasarkan rumus Slovin yaitu 74, dari 36 siswa putra dan 38 siswa putri. Hasil temuan penelitian menunjukkan nilai passing bawah putra dan putri adalah kurang sekali jumlah siswa putra 61 persen, putri 29 siswa 76 persen. Passing atas putra dan putri yaitu kurang sekali jumlah siswa putra 21 persentase 58 persen, putri 18 siswa 47 persen. Sehingga disimpulkan bahwa sebagian besar siswa dalam melakukan passing putra dan putri yaitu kategori kurang sekali.
Usage of iron foliar spray in enhancing the growth and yield of the flax plant (Linum usitatissimum L)
Authors: Gondal Aqarab Husnain , Areche Franklin Ore , Sumarriva-Bustinza Liliana Asunción , Chávez-Sumarriva Nadia Lys , Zela-Payi Nelly Olga , More López Jesús Manuel , Saldarriaga José Yovera , García-Díaz Bertila Liduvina , Porras-Roque María Soledad , Ayuque-Rojas Jose Carlos , Aguilar Salomón Vivanco , Vilchez David Ruiz , Yaulilahua-Huacho Russbelt , Malpartida Yapias Rafael Julian , Jabbar Abdul
Published: May 2023

The ideal growth and development of linseed plants depend on receiving the necessary nutrients during the growing season when they are grown. Flax's yield and oil content increase using a foliar spray containing micronutrients. This study aimed to determine how foliar iron (Fe) treatment affected flax yield and its constituents. The experiment was set up at the adoptive research farm Sargodha in a randomized block design and three replicates. At the capsule filling stages and bud initiation of the flax crop, foliar sprays with varying concentrations of Fe (5.5%, 4.5%, 3.5%, 2.5%, 1.5%) and without Fe (control) were administered. Sulphate of iron (Fe) was used as the source of Fe. All treatments resulted in notable enhancements in agronomic characteristics such as grain oil contents, harvest index, biological yield, number of capsule formations, technical stem length, plant height, as well as physiological parameters including fluorescence yield (Ft), quantum yield (YII), photosynthetically active radiation (PAR), electron transport rate (ETR), and chlorophyll contents. The results of this study suggested that the application of 3.5% to flax during the bud initiation and capsule filling stages increases the seed yield, yield attributes, and oil contents. In conclusion, foliar spray of Fe could enhance the yield of linseed crops.