bluuebunny/crossref_metadata_2025 huggingface dataset:
Bill Viola’s figures of submersion as techniques of transindividual affect
Authors: del Río Elena
Published: July 2022

This article seeks to establish a fundamental continuity between distinctive periods in Bill Viola’s work. Examining two relatively early works—The Reflecting Pool (1977–79) and The Passing (1991)—and the more recent piece Self Portrait, Submerged (2013), I consider the artist’s physical presence as a catalyst for an inherent continuity between early formalism and the intense affectivity of the later period. Affect and its transindividual energies were present in Viola even before they came to acquire a more explicit articulation in the 2000s and beyond. We see in Viola’s work a merging of artist and artwork which drastically departs from traditional notions of authorial autonomy and mediation, giving rise instead to an event of transindividual affect. I consider the merging of artist and artwork here in light of Gilbert Simondon’s philosophy of individuation, a process-oriented ontology remarkably resonant with Viola’s art. I rely on Simondon’s concepts of the technical object, the preindividual and the transindividual, to examine: first, Viola’s immanent, transductive relation to his medium as illustrated in The Reflecting Pool; second, the way in which the artist’s participatory witnessing of technological ontogenesis transmutes into a directly affective experience in The Passing; and finally, the confluent affectivity of artist and spectator in Self Portrait, Submerged.
MARGINAL TOPICS IN THE RESEARCH OF SCIENCE EDUCATION
Authors: Kubiatko Milan
Published: July 2022

The researchers all over the world are focused on different topics. Many of them have got a character of “mainstream”. When the reader is searching for science education journals, it is possible to find some research areas typical for every science subject (physics, chemistry, etc.). One of the topics is the problems connected with wrong ideas/preconceptions/misconceptions among different age groups, from elementary school pupils through high school pupils till university students and adult population.
Improved outcomes with “7+3” induction chemotherapy for acute myeloid leukemia over the past four decades: analysis of SWOG trial data
Authors: Othus Megan , Garcia-Manero Guillermo , Godwin John E. , Weick James K. , Appelbaum Frederick R. , Erba Harry P. , Estey Elihu H.
Published: July 2022

We have previously shown that complete response (CR) rates and overall survival of patients with acute myeloid leukemia have improved since the 1980s. However, we have not previously evaluated how the length of first CR (CR1) has changed over this time period. To address this, we analyzed 1,247 patients aged 65 or younger randomized to "7+3" arms from five SWOG studies: S8600 (n=530), S9031 (n=98), S9333 (n=57), S0106 (n=301), and S1203 (n=261). We evaluated length of CR1 and survival after relapse from CR1 over the four decades that these studies represent. Both length of CR1 and survival after relapse from CR1 have improved over the last four decades. The relative benefit associated with CR1 and the relative detriment associated with relapse have decreased over this period; while achieving CR1 and relapse from CR1 still have strong prognostic associations with outcomes, the magnitude of the association has decreased over time. Possible explanations for these patterns include higher CR rates with salvage therapies after relapse, more frequent use of hematopoietic cell transplant, and better supportive care.
Allogeneic transplant following CAR T-cell therapy for large B-cell lymphoma
Authors: Zurko Joanna , Ramdial Jeremy , Shadman Mazyar , Ahmed Sairah , Szabo Aniko , Iovino Lorenzo , Tomas Ana Alarcon , Sauter Craig , Perales Miguel-Angel , Shah Nirav. N. , Acharya Utkarsh H. , Jacobson Caron , Soiffer Robert J. , Wang Trent , Komanduri Krishna V. , Jaglowski Samantha , Kittai Adam S. , Denlinger Nathan , Iqbal Madiha , Kharfan-Dabaja Mohamed A. , Ayala Ernesto , Chavez Julio , Jain Michael , Locke Frederick L. , Samara Yazeed , Budde Lihua E. , Mei Matthew G. , Pia Alexandra Della , Feldman Tatyana , Ahmed Nausheen , Jacobs Ryan , Ghosh Nilanjan , Dholaria Bhagirathbhai , Oluwole Olalekan O. , Hess Brian , Hassan Ayesha , Kenkre Vaishalee P. , Reagan Patrick , Awan Farrukh , Nieto Yago , Hamadani Mehdi , Herrera Alex F.
Published: July 2022

Allogeneic hematopoietic cell transplantation (alloHCT) can potentially salvage large B-cell lymphoma (LBCL) patients experiencing treatment failure after chimeric antigen receptor T-cell therapy (CAR T). Nonetheless, data on the efficacy and toxicities of alloHCT after receipt of CAR T are limited. We report a multicenter retrospective study assessing the safety, toxicities, and outcomes of alloHCT in LBCL patients following CAR T failure. Eighty-eight patients with relapsed, refractory LBCL received an alloHCT following anti-CD19 CAR T failure. The median number of lines of therapy between CAR T infusion and alloHCT was one (range, 0-7). Low intensity conditioning was used in 77% (n=68) and peripheral blood was the most common graft source (86%, n=76). The most common donor types were matched unrelated donor (39%), followed by haploidentical (30%) and matched related donor (26%). Median follow-up of survivors was 15 months (range, 1-72). One-year overall survival, progression-free survival, and graft-versus-host disease-free relapse-free survival were 59%, 45%, and 39% respectively. One-year non-relapse mortality and progression/relapse were 22% and 33% respectively. On multivariate analysis, <2 lines of intervening therapy between CAR T and alloHCT and complete response at time of alloHCT were associated with better outcomes. In conclusion, alloHCT after CAR T failure can provide durable remissions in a subset of patients.
The Existence of PAI Teachers in PAI Learning during the Covid-19 Pandemic
Authors: Devi Indah Sari  , Aulia Ramadhani Lubis
Published: July 2022

This study aims to elaborate further on the role of PAI teachers in the midst of a pandemic, the strategies used, the obstacles encountered, the efforts made and what are the challenges for PAI teachers in carrying out their duties in the midst of the Covid-19 pandemic. This study uses a type of qualitative research method. Kirk and Miller define that qualitative research is a particular tradition in the social sciences that is fundamentally dependent on observations of humans both in terms of their area and in terms. This study uses a qualitative method because the researcher considers the problem under study to be quite complex and dynamic so that the data obtained from the informants is captured by a more natural method, namely direct interviews with the informants so that natural answers are obtained. In addition, the researcher intends to understand the social situation in depth, find patterns and theories that are in accordance with the data obtained in the field.
ДВОФАЗНА СУМІШ У РУХОМОМУ ПАРАЛЕЛЕПІПЕДІ ПРИ ІМПУЛЬСНОМУ ВПЛИВОВІ
Authors: Ткаченко Н.
Published: July 2022

У статті визначено, що задачі динаміки двофазних сумішей є важливими та актуальними для сучасної промисловості. Рухомість рідини впливає на керованість відповідних об‘єктів.
У статті проведено порівняльний аналіз динамічних процесів у двофазній суміші в нерухомому та рухомому прямокутних паралелепіпедах при зовнішньому імпульсному впливові, використовуючи математичну модель, побудовану на основі кінетичного підходу. Проведено порівняння середніх характеристик руху системи частинок у рухомому та нерухомому паралелепіпедах.
Досліджено рух системи рідина-частинки в рухомому паралелепіпеді, обумовлений вводом частинок у рідину і прикладанням імпульсивного тиску на вільній поверхні рідини, використовуючи модель двофазного середовища рідина-частинки, яка побудована на основі статистичного підходу. Знайдено закон розподілу середньої густини частинок на кінетичному та дифузійному режимі.
Ключові слова: двофазна суміш, кінетичний підхід, рухомий прямокутний паралелепіпед, густина розподілу.
УЧЕТ ПОГРЕШНОСТЕЙ ДИСТАНЦИИ И ВРЕМЕНИ КРАТЧАЙШЕГО СБЛИЖЕНИЯ ПРИ РАСХОЖДЕНИИ СУДОВ
Authors: Ганиев А.
Published: July 2022

Основными критериями для определения безопасного расхождения судов являются дистанция и время кратчайшего сближения. Поэтому основной задачей является определение и учет погрешностей, влияющих на значения этих параметров.
В данной статье рассмотрены основные параметры безопасности при расхождении судов на ограниченной акватории и в ограниченной видимости, составлена программа для расчета расхождения судов с учетом погрешностей дистанции и времени кратчайшего сближения.
Основным преимуществом программы является то, что она не только рассчитывает параметры опасного сближения и этим самым сокращает время, но и учитывает их погрешности, что имеет важное значение при следовании судов на ограниченной акватории. Судоводителю для определения основных критериев безопасности с учетом погрешностей нужно лишь ввести данные судна, цели и погрешности используемых приборов.
Ключевые слова: дистанция кратчайшего сближения, время кратчайшего сближения, фактор, судоводитель, авария, ограниченная акватория, ограниченная видимость, расхождение.
Análise das ações e estratégias de educação em saúde bucal como promoção de saúde no período gestacional: uma revisão integrativa
Authors: Limeira Arthur Barbosa Palmeira , Medrado Filho Nilton Freitas , Almeida Wellington Gabriel Silva de , Soares Samara Carollyne Mafra
Published: July 2022

Objetivo: analisar por meio das publicações científicas como estão sendo realizadas as ações e estratégias de educação em saúde bucal que se encontram em fase de proposta ou ainda aquelas que já obtiveram resultados sobre o atendimento do pré-natal odontológico com gestantes brasileiras no âmbito do Sistema Único de Saúde. Métodos: Trata-se de uma revisão integrativa da literatura, cujos dados foram coletados a partir de fontes primárias, por meio de levantamento bibliográfico nas bases de dados Biblioteca Virtual em Saúde (BVS), Google Scholar e Scientific Electronic Library Online (SciELO). Foram incluídos estudos originais que apresentavam propostas de ações e estratégias visando a melhoria do conhecimento das gestantes sobre saúde bucal e foram excluídos estudos de metanálise, revisões sistemáticas, revisões da literatura. Resultados: Dentre os 400 achados e após utilização de filtros, leitura de títulos e resumos, utilizaram-se 14 estudos para compor a revisão. Discussão: Os achados demonstraram que as principais estratégias de educação em saúde bucal se concentram em rodas de conversas para desmistificação de medos da consulta com o cirurgião-dentista durante a gestação, palestras e orientações sobre amamentação, escovação e utilização do fio dental.  Considerações finais: A análise dos estudos incluídos sobre ações e estratégias de educação em saúde bucal para gestantes brasileiras demonstra que trabalhos vêm sendo desenvolvidos pelos profissionais permeados pelas mudanças do SUS ao longo do tempo. Entretanto, em relação ao acesso às ações de saúde bucal das gestantes, foi visto uma certa dificuldade. Observou-se que as gestantes ainda possuem uma certa insegurança quanto ao atendimento odontológico durante o período gestacional.
New technologies in pasture and grazing management in the face of climate change perspectives
Authors: Prudencio Marcelo Falaci , Freitas Gabriela da Silva , Soares Filho Cecílio Viega
Published: July 2022

The search for sustainable livestock farming has been the focus of several researches in Brazil and worldwide, in face of climate change. Livestock production is mostly explored in pastures in Brazil. It is estimated that a large part of these pastures presents some kind of degradation, as a result of its incorrect management. With this degradation, besides reducing productivity, there is loss of soil organic matter and CO2 emission to the atmosphere, with a reduction in carbon sequestration by the pasture. Consequently, there is the release of excess enteric methane, which occurs in the digestive process of ruminants, by fermentation of fibrous and poor quality food ingested by these animals from this pasture. Several studies propose new technologies to mitigate greenhouse gases, with intensive pasture management, processing and conservation of forage to reduce particle size and increase digestibility. Recovery and renovation of pastures, using integrated production systems with grain, forest, and forage production. Implementation of pasture with forage in suitable environments and use of grasses with better leaf/stem ratio. Use of rotational grazing with height control of animals entering and leaving each forage species in order to produce a better and more digestible forage. With this, reduce the precursors of greenhouse gases to mitigate the possible effects on climate change.
The Brazilian State has assured the human right to adequate food for people with celiac disease?
Authors: Siqueira Renata Lopes de , Freitas Dayse Mara de Oliveira , Fernandino Sophia Sol Garcia , Cruz Pedro Siqueira , Oliveira Cassia Bonfim de , Fraga Layanne Nascimento , Carvalho Izabela Maria Montezano de
Published: July 2022

Introduction: By assuming adequate food as a social right, the Brazilian State became the bearer of the duty to respect, provide, promote and protect the Human Right to Adequate Food (HRAF) for all Brazilians, including celiacs. Therefore, it is essential that the State institute a normative apparatus compatible with the needs of the celiac population, guaranteeing the fulfillment of their rights. Objective: to assess whether the legislation in force in Brazil meets the demands of people with celiac disease. Methods: document analysis was adopted according to the methodology proposed by Pimentel. The set of documents analyzed is composed of all publications found that express the demands of celiacs, including: articles, manuals and complaint letters from representative bodies. Results: The incipience of legal instruments was observed, aggravated by the fact that a significant portion of the demands of the celiac population has not yet been covered by the current set of regulations. The legislation in force expresses the existence of specific initiatives in some Brazilian states and municipalities, which do not cover the entire national territory. This situation does not comply with the principle of universality that governs the HRAF, compromising the demand for compliance and reparation by public bodies for the celiac population. Conclusion: due to the punctual and incipient nature of the Brazilian legal apparatus, it remains predominantly the responsibility of civil society, individually or through representative associations, initiatives that guarantee the realization of the Human Right to Adequate Food for celiacs.
Avaliação das características químicas e físicas da farinha da abóbora moranga (Cucurbita maxima): polpa e sementes
Authors: Gomes Elienae da Silva , Marins Annecler Rech de , Gomes Raquel Guttierres
Published: July 2022

A abóbora moranga (Cucurbita maxima) é popular no Brasil estando entre as três variedades que se destacam com maior consumo no país. A polpa da abóbora é considerada rica em antioxidantes naturais, os carotenóides. Os humanos não sintetizam este pigmento, assim a necessidade do mesmo é satisfeita pela ingestão de alimentos contendo caroteno. As sementes da também possuem teor de carotenóides, além de fenólicos totais, flavonóides e teores minerais, destacando a quantidade de Zinco. Além dos produtos já existentes no mercado, a base de abóbora moranga, existe ainda o potencial da farinha de abóbora para ser utilizada como ingrediente em pães, produtos assados e massas sem glúten. O objetivo deste trabalho foi o desenvolvimento da farinha da polpa e das sementes da abóbora moranga, buscando o melhor binômio tempo/temperatura para a desidratação e a realização das análises físico-químicas. A umidade da farinha da polpa foi considerada dentro do estabelecido pela Anvisa. O valor de cinzas não diferiu entre as amostras de farinha de polpa e semente. Já o teor de proteína foi maior na farinha de semente, assim como a acidez titulável e o teor zinco de fibras total. A composição mineral a farinha da semente se destacou devido ao elevado conteúdo de zinco. A partir das curvas de secagem foi possível observar que a temperatura mais elevada permitiu um menor tempo de secagem, o que a tornaria melhor economicamente. As farinhas apresentaram teor elevado de minerais e matéria orgânica o que as tornam uma alternativa comercial atrativa e viável.
Relação entre a carga de trabalho e sintomas no teste ergométrico em pacientes com doenças pulmonares intersticiais e em indivíduos saudáveis
Authors: Bertin Larissa Dragonetti , Jorge Marcela Paes , Fan Otávio Goulart , Gois Junior Emanuel , Zamboti Camile Ludovico , Krinski Gabriela Garcia , Pimpão Heloise Angélico , Pitta Fabio , Camillo Carlos Augusto
Published: July 2022

Introdução: As doenças pulmonares intersticiais (DPI) apresentam características clínicas semelhantes caracterizadas por dispneia e intolerância ao exercício. Essas características se acentuam durante o esforço físico, embora isso ainda não tenha sido investigado em profundidade nessa população. Objetivos: Comparar a sensação subjetiva de dispneia e fadiga por carga de trabalho durante o teste ergométrico (TE) entre pacientes com DPI e indivíduos saudáveis. Métodos: Os indivíduos realizaram o TE em cicloergômetro com protocolo incremental. A cada estágio do teste foram coletados a sensação de esforço pela escala de Borg de dispneia (D) e fadiga (F). As inclinações das curvas de D e F por estágio no teste foram comparadas por meio de regressão linear utilizando o método Zar (teste F). Resultados: Foram estudados 37 pacientes com DPI e 29 controles. O grupo DPI apresentou menor carga máxima (60[40-80] vs saudáveis 120[100-160]; (P<.0001) e maiores sintomas ao final do teste para D (P=0,02), mas não para F (P=0,23) quando comparados ao controle. Ainda, o grupo DPI apresentou mais sintomas por watt (i.e. Borg/Wattts) no TE comparado ao grupo controle para D (8x10-2±7x10-2 vs 2x10-2 ± 2x10-2; P=0,0007) e F (1x10-1± 9x10-2 vs 3x10-2 ± 1x10-2; P=0,001). A inclinação das curvas Borg/watts diferiu entre os grupos, com DPI apresentando mais sintomas de D e F por watt (P<0.05 entre as curvas). Conclusão: Pacientes com DPI apresentarem menor capacidade máxima de exercício e parecem apresentar um aumento mais acentuado na sensação de D e F por carga de trabalho durante o TE.
Inovações e tecnologias no trabalho do fisioterapeuta no fortalecimento pélvico
Authors: Silva Eliane Candida da , Castro Karollainy Sousa de , Silva Karla Camila Correia da
Published: July 2022

Introdução: A fisioterapia pélvica é um tema importante para a melhoria dos serviços da área da fisioterapia, pois tem como tratamento o uso de técnicas manuais e tecnologias para sanar problemas sexuais que atingem as mulheres ao longo de suas vidas. O trabalho do profissional de fisioterapia no fortalecimento e recuperação perineal do assoalho pélvico passa a objetivar a melhoria na força de contração dos músculos perineais e a prevenção de disfunções e incontinências libidinosas. Objetivo: Conhecer as inovações e tecnologias utilizadas para o uso do fisioterapeuta no fortalecimento pélvico. Metodologia: Estudo bibliográfico de abordagem qualitativa descritiva, sendo pesquisados 33 artigos nas bases de dados, sendo: Scribd, PubMed, Scielo, realizadas entre os anos 2000 e 2022. Resultados: É necessário que se conheça as respectivas estruturas e ferramentas utilizadas para o tratamento dos tipos de disfunções e de seus principais sintomas. Por meio de treinos de fortalecimento, é possível desenvolver o aumento do diâmetro e força de fibras dos músculos do assoalho pélvico. Conclusão: O uso dos instrumentos é de suma importância para reintegrar a mulher à sua vida sexual e à sociedade objetivando maior velocidade e eficiência ao fortalecer a musculatura pélvica.
Efeitos adversos no uso indiscriminado de medicamentos na pandemia da COVID-19: um olhar sobre a cloroquina, hidroxicloroquina e azitromicina
Authors: Costa Jesus Eden Bezerra da , Rodrigues Junior Omero Martins , Almeida Pablo Henrique Freitas de , Magalhães Méllory Nétaly de Oliveira , Botero Beatriz Fonseca , Silva Ytalo Thiago Praciano da , Santos Pâmela Bianca Barbosa dos , Lima Maria Alves de
Published: July 2022

Objetivo: o presente estudo buscou analisar as evidências científicas existentes até o presente momento sobre efeitos adversos no uso indiscriminado da cloroquina, hidroxicloroquina e azitromicina na pandemia da COVID-19. Material e Método: Tratou-se de uma revisão integrativa de literatura junto às bases de dados LILACS, PUBMED/MEDELINE e SCIELO, entre 2019 e 2022. Identificaram-se 75 artigos, sendo 10 utilizados na elaboração do trabalho.Resultados mostram que a literatura científica sobre a eficácia dos medicamentos cloroquina, hidroxicloroquina e azitromicina no tratamento da COVID-19 é escassa , devido à rápida disseminação e instalação da pandemia em todo o mundo. Há necessidade de ensaios clínicos pragmáticos envolvendo um número maior de pacientes para analisar a eficácia do combate ao coronavírus e a segurança do uso desses medicamentos.
Análise da evolução de manifestações patológicas em túneis da cidade do Recife-PE
Authors: Guerra Arthur de Moura Dourado , Lins Eduardo José Melo , Moura Júnior José Maria de , Cavalcanti Lucas Rodrigues , Santos José Mickael Silvestre dos
Published: July 2022

As manutenções preventivas são fundamentais para o bom desempenho de qualquer obra de engenharia, principalmente em se tratando obras de arte especiais (OAEs). Os túneis mais recentes da cidade do Recife têm apresentado manifestações patológicas intensas, em mesmo grau de risco dos seus semelhantes mais antigos e providências devem ser tomadas. O objetivo do trabalho consiste em inspecionar visualmente os túneis e transmitir a evolução, entre os anos 2017 e 2021, dos problemas decorrentes de falta de manutenção e manifestações patológicas dos Túneis da Abolição e Felipe Camarão. Através de pesquisas bibliográficas foi possível obter dados referentes aos níveis de conservação de quatro anos antes e, assim, realizar análise comparativa. Das inspeções, ficou notório que as passagens inferiores em questão seguem apresentando falhas de manutenção e manifestações patológicas: pichações, percolação de água com carreamento de aterro, eflorescências e criptoflorescências, vegetação e bolor, lixiviação do concreto com produto de corrosão, alagamentos por falha do sistema de drenagem, além de fissuras de tipologia variada. A piora do estado de conservação é sensível, por isso, a realização de inspeções é essencial para revelar os problemas existentes nestas obras de arte especiais. Estudos como este devem ser reproduzidos nos demais túneis urbanos da cidade do Recife, acrescentando a realização de ensaios ao escopo dos trabalhos a fim de contribuir com o fornecimento de subsídios que possibilitem o planejamento e execução de ações de manutenção eficientes capazes de garantir a devida funcionalidade destas obras ao longo de suas vidas úteis.
Projetos sociais esportivos e a resiliência: um estudo de revisão
Authors: Monteiro Luciana Bernardes Vieira de Rezende Hersen , Silva Carlos Alberto Figueiredo , Osborne Renata , Araújo Carla Isabel Paula da Rocha
Published: July 2022

O objetivo desta pesquisa foi investigar na literatura as contribuições dos projetos sociais esportivos (PSE) e sua ligação com o desenvolvimento da imagem corporal dos discentes e a promoção da resiliência através do esporte. Trata-se de uma revisão narrativa da literatura, onde se buscou um caminho que apresentasse estudos de vertentes dos PSE, colhendo, especialmente, os textos que abordassem a resiliência. Os PSE, por serem um tema recente, ainda têm uma literatura escassa. A resiliência também é um tema novo e que precisa de mais estudos. Mais escassa ainda é a temática da resiliência em PSE, havendo uma grande lacuna a ser preenchida. Os estudos encontrados apresentam, em grande parte, que os PSE proporcionam benefícios graças à prática regular esportiva e colaboração na formação moral dos seus alunos; porém, há também um “lado sombra do esporte”, mostrando que muitos dos PSE são paliativos, pois possuem objetivos rasos e sem finalidades claras. Para uma melhor análise da contribuição dos PSE e o desenvolvimento da resiliência, faz-se necessário mais estudos que relacionem estas temáticas, pois o material encontrado, ainda é pouco. Mesmo assim, este artigo apresenta os conceitos mais usados relacionados a estes temas, tentando contribuir para uma maior discussão. Como muitos jovens atendidos pelos PSE são sujeitos em vulnerabilidade social, que cotidianamente sofrem diversos traumas ligados as suas condições sociais e culturais, para que consigam sair da imobilização causada por esses traumas, e que aconteça a superação dessas adversidades, havendo uma ressignificação de sua imagem corporal: há necessidade de um potencial de reação, processo conhecido como resiliência. Assim, os PSE podem ser uma importante ferramenta na promoção da resiliência de seus alunos, por serem um alicerce para a superação de adversidades.
Leishmaniose Tegumentar: panorama epidemiológico em região do Nordeste brasileiro, Região Metropolitana da Grande São Luís (2010-2020)
Authors: Aguiar Antônio Henrique Braga Martins de , Barbosa Wesley Lima , Caldas José Manuel Peixoto , Pinheiro Maria do Socorro Saraiva
Published: July 2022

Introdução: Leishmaniose Tegumentar é uma doença parasitária que apresenta alta incidência em regiões de clima tropical e subtropical. Ao longo dos anos apresenta alta expansão em todas as regiões brasileiras, com destaque para o Norte e Nordeste que evidencia populações vulneráveis como as mais atingidas. Investigar a epidemiologia destas doenças são fundamentais para a formulação e implementação de políticas públicas de saúde com o objetivo de prevenção e combate ao inseto vetor. Objetivo: Descrever os dados epidemiológicos e sua relação com variáveis sociodemográficas em relação à incidência de Leishmaniose Tegumentar na Região Metropolitana da Grande São Luís entre os anos de 2010 a 2020. Metodologia: Estudo epidemiológico de abordagem quantitativa e retrospectiva que utilizou dados secundários em relação aos casos confirmados da doença entre os anos de 2010 a 2020 para a região de estudo e variáveis qualitativas. Resultados: Os dados mostraram maior incidência da doença em indivíduos do sexo masculino, de cor parda e com ensino fundamental incompleto. Conclusão: Ações desenvolvidas por parte das esferas públicas com o objetivo de divulgação de campanhas preventivas associadas a investimento financeiro e técnico às universidades e centros de pesquisa contribuem para o desenvolvimento de pesquisas e elaboração de medidas que atuem nas interfaces de prevenção, tratamento, controle e erradicação das principais doenças tropicais negligenciadas.
Asynchronized spawning responses of small pelagic fishes to a short-term environmental change
Authors: Tiedemann M , Ndour I , Sow FN , Bagøien E , Krakstad JO , Ostrowski M , Stenevik EK , Ensrud T , Isari S
Published: July 2022

We provide substantial evidence on how short-term changes in environmental conditions activate and deactivate spawning activities in small pelagic fishes. An ichthyoplankton survey was conducted along the southernmost part of the Canary Current upwelling ecosystem in May 2013, covering the area twice within 20 d. This period coincided with a strong environmental change from a cold productive upwelling regime to a warmer and less productive upwelling relaxation event. This change triggered a shift in spawning activity from European anchovy Engraulis encrasicolus to round/flat sardinella Sardinella spp. We used zero-altered negative binomial regression models with a generalized additive structure based on integrated nested Laplace approximations to link early larval distribution patterns to the 2 different regimes. The models confirmed 2 species-specific temperature spawning windows, suggesting a spawning pause of anchovy during upwelling relaxation while simultaneously activating spawning in sardinella. Observing immediate spawning responses to the 2 environmental regimes underlines the assumption that windows of spawning opportunity are the main drivers of small pelagic fish fluctuations in upwelling regions. The duration of a specific environmental condition can, therefore, increase or decrease the chances for reproductive success. The observations of this study may explain why certain small pelagic fish species can dominate over others during a particular period and might also apply to other upwelling regions of the world oceans where upwelling and relaxation events alternate.
Perencanaan Bangunan Pelindung Pantai di Kawasan Pantai Pesaren Belinyu Provinsi Kepulauan Bangka Belitung
Authors: Lestari Atiqoh Dwi , Hisyam Endang Setyawati , Gunawan Indra
Published: July 2022

Pantai Pesaren merupakan salah satu pantai yang ada di Desa Bintet, Kecamatan Belinyu, Provinsi Kepulauan Bangka Belitung yang berfungsi sebagai kawasan wisata dan pelabuhan perahu bagi para nelayan. Permasalahan yang sering terjadi di Pantai Pesaren yaitu terjadinya abrasi yang menyebabkan kerusakan pada infrastruktur yang telah ada, sehingga rencana perlindungan pantai diperlukan untuk dapat mencegah kerugian lebih lanjut. Tujuan dari penelitian ini yaitu untuk mengetahui pola arus dan sedimen menggunakan bantuan aplikasi pemodelan, serta untuk menentukan dan merencanakan tipe bangunan pelindung pantai yang sesuai dengan kondisi di kawasan Pantai Pesaren. Metode penelitian dilakukan dengan menganalisis hidro-oceanografi berupa pasang surut, gelombang, pemodelan arus dan transpor sedimen menggunakan aplikasi software 2D. Berdasarkan analisis perencanaan, didapatkan penyebab dominan terjadinya abrasi yaitu gelombang besar dari arah utara dan penyebab lainnya yaitu arah arus dan sedimen dominan tegak lurus pantai sehingga untuk tipe dan bentuk dari bangunan pelindung pantai terpilih yaitu breakwater / pemecah gelombang sisi miring dengan tinggi (HT) sebesar 5,2 m, lebar puncak (lp) sebesar 1,5 m, total lebar dasar (b) sebesar 26,7 m, panjang breakwater (ly) sebesar 350 m, lebar lapis lindung (t) sebesar 1 m, jumlah batu per 10 m² (N) sebanyak 86 butir, berat butir batu lapis utama (W) sebesar 0,179 ton, berat butir batu lapis kedua (W/10) sebesar 0,0179 ton, berat butir batu di inti struktur (W/200) sebesar 0,000895 ton dan  berat butir kaki pemecah gelombang (W/15) sebesar 0,0119 ton.
STUDY OF THE EFFECT OF THE USE OF ADDITIONAL ADDITIVES DAMDEX AND BESTMITTEL ON THE COMPRESSIVE STRENGTH OF CONCRETE f'c 20 MPa.
Authors: Heldita Dina
Published: July 2022

Under normal circumstances, the maximum strength of the concrete will be reached at the age of 28 days, but to achieve the initial maximum strength of the concrete can be done in 2 ways, namely the use of Portland cement or the use of mineral additives or chemical admixtures. Another purpose of the use of admixture is the fulfillment of a short concrete execution time but the performance of the concrete is maintained.This study aims to determine the comparison of the compressive strength (N/mm2 unit) of normal concrete with concrete that uses Damdex and Bestmittel added materials, the test object used is cylindrical with the percentage addition of Damdex 2% and Bestmittel 0.2% of the weight of cement with composition the mixture used using the Job Mix Formula f'c 20 MPa for the Block B/F Heavy Rehab work project, Kotabaru District Prosperity Market Complex, namely for 1 m3 using 442.00 kg of cement, 681.79 kg of fine aggregate, 1065.72 kg of coarse aggregate , 215 liters of water. With the age of the tested concrete the compressive strength is 14 and 28 days.The results of the normal concrete compressive strength test at 14 and 28 days on average were 20.33 MPa and 22.19 MPa from the design compressive strength (f'c) of 20 MPa. Meanwhile, for the mixture with 2% Damdex and Bestmittel 0.2% added materials at 14 and 28 days the average was 22.93 MPa and 20.76 MPa from the design compressive strength (f'c) 20 MPa..Keywords: Concrete Quality, Damdex, Bestmittel, Compressive Strength
Using Problem-Based Learning to Develop EFL Pre-service Teachers’ Intercultural Awareness
Authors: Misdi Misdi , Mahaputri Ratna Andhika
Published: July 2022

This article reports an on-going research project dealing with intercultural issue that has conducted in the department of English education in a private university. In the framework of case study, this study attempts to describe how students were involved and shared their insights of intercultural learning in the classroom. Forty EFL pre-service teachers were recruited and involved in the current study. The data were drawn from the classroom observation. From the categorized data, critical incidents were captured and interpreted. The findings show the students’ sense of intercultural awareness developed. It concludes this problem-based learning provides authentic and meaningful learning as the students were engaged in real-lives related projects of intercultural exchangesArtikel ini merupakan sebagian laporan dari riset tentang kompetensi lintas budaya yand dilaksanakan di sebuah perguruan tinggi swasta di Cirebon-Indonesia. Dalam kerangka studi kasus, riset ini bertujuan untuk mendeskripsikan bagaimana mahasiswa calon guru terlibat dalam diskusi kasus lintas budaya yang diberikan di dalam kelas. Empat puluh mahasiswa calon guru bahasa Inggris direkrut dan terlibat dalam riset. Semua partisipan telah melalui dan memberikan persetujuan merekan untuk secara suka rela terlibat dalam proyek riset ini. Semua data dikumpulkan dari hasil observasi kelas dan hasilnya diintepretasokan dari setiap critical incident yang muncul. Hasil riset menjelaskan bahwa kemampuan komunikasi lintas budaya mahasiswa semakin terbangun. Hasil ini berkesimpulan bahwa problem-based learning merupakan pembelajaran yang penuh kebermaknaan dan pembelajaran yang otentik yang membuat mahasiswa terlibat dalam proyek-proyek yang menyentuh kehidupan langsung terkait dengan interaksi lintas budaya
Suitability of Ugur and Alinja Vine Varieties as Planting Stock
Authors: Alekperova M. , Aslanova F.
Published: July 2022

One of the main reasons for the delay in the development of viticulture in the country in recent years is the lack of high-quality planting material. For many years, the issue of providing viticulture in Azerbaijan with high-quality planting material remained unresolved, since the material and technical base of the farms producing planting material was rather weak In vineyards, targeted measures are already being taken to address this problem. Thus, in some farms, in order to expand vineyards, on-farm seedlings are planted, as well as seedlings imported from abroad and grown on their own roots. In connection with the “Strategic roadmap for the production and processing of agricultural products in the Republic of Azerbaijan”, the expansion of vineyards in the country until 2020 was taken as a strategic goal. Therefore, our republic needs nurseries. In order to organize a nursery, it is necessary to produce high-quality planting material. To do this, it is necessary to determine the quality indicators of the supplied seedlings and the characteristics of suitability for planting material. Depending on the climatic conditions in Azerbaijan, seedlings are supplied from approved orchards and nurseries from autumn to early spring. The accuracy of the name of the variety cultivated in the vineyard or the future planting material is taken as the basis, and the degree of susceptibility of the bushes to diseases and pests is also determined. In our studies, we also analyzed the quality indicators of the supplied seedlings of the Ugur and Alinja varieties from the Nakhchivan, and their suitability for planting material.
Tomatoes Cultivation Under Conditions of a Managed Farming Systems
Authors: Muradov R. , Ubaydillayev A.,
Published: July 2022

The aim of the work is to assess the impact of resource-saving irrigation technologies on water consumption, excavation depth, degree of salinity, duration of the light period, crop density and temperature changes when growing tomato in a managed farming system. The subject of the study is the factors affecting of the Lamia F1 variety tomato yield and water consumption (irrigation rate, soil salinity, excavation depth, duration of the light period, seedling density, temperature changes). Research objectives: to study the influence of managed farming system indicators (light period duration, greenhouse depth, seedling stem thickness, difference between day and night temperatures, salinity degree, irrigation rate) on tomato yield and seasonal irrigation rate; conducting experiments with fractional factorization of tomato yields and seasonal irrigation rates in accordance with managed farming system; development of an irrigation regime for the Lamia F1 variety of tomato culture according to the FAO method for managed farming system conditions; mathematical modeling of the dynamics of soil moisture, the consumption of nutrients when growing tomato crops under managed farming system conditions. The effect of the seasonal irrigation norm, the degree of soil salinity, the depth of the greenhouse, the length of the light period, the thickness of the stem of tomato seedlings, the difference between the maximum and minimum temperatures on the tomato yield of is substantiated; an irrigation regime for tomato crops has been developed based on the FAO method, taking into account managed farming system indicators; mathematical models of thermal regime processes, soil moisture dynamics, nutrient consumption in tomato cultivation under managed farming system conditions have been developed.
Modeling and Experimental Study of the Cow Skin Mechanical Cleaning Process
Authors: Juvarlinskaya E. , Mammadov G.
Published: July 2022

First of all, the contact of the organism with the environment occurs through it. Numerous sensory receptors perceive thermal, mechanical, light and pain stimuli. In order for the skin to fully perform its functions, it must be properly cared for. When animals are kept in the right conditions and their body is sanitized, their resistance to external effects increases. It should be noted that the technology and technological equipment developed for animal husbandry are insufficiently physiologically related to them. In addition, the researchers did not consider the animal as an element of a system with high genetic and neural information, as a result of which the animal was considered as a separate engineering and biological object, and not as a whole object of research. Attempts to compensate for the incompatibility of the technical element with physiological processes by instinctive requirements and behavioral reaction of the animal were unsuccessful. The purpose of this study was to constructively and technologically substantiate the mechanical cleaning of cow skins using a mathematical model and experiment. To construct a mathematical model of the development of such a complex biotechnical system as mechanical cleaning of the cow skin surface, a systematic approach based on formal methods was chosen: informational, functional and physiological signs. Preliminary experimental studies show that the quality of skin cleaning has many process parameters: constructive (length of cleaning elements, bending, modulus of elasticity, diameter of the rod of the working part), quality indicators (skin contamination), operating parameters (vacuum price, air consumption, movement of the device, speed). Therefore, the second stage of the experimental study included the study of the experimental scheme developed on the basis of a working hypothesis. The results obtained made it possible to establish the response surface, to determine the dependence of the desired parameters on a group of factors. Analyzing this surface, it is possible to draw conclusions about the optimal values of design and operating parameters.
Computational Method and Calculus for the Summation of Geometric Series and Binomial Expansions
Authors: Annamalai Chinnaraji
Published: July 2022

This paper presents computational method and differential and integral calculus for the summation of geometric series and binomial expansions in an innovative way and also theorems and relationship between the binomial expansions and geometric series. This computational technique refers to the methodological advance which is useful for researchers who are working in computational science. Computational science is a rapidly growing multi-and inter-disciplinary area where science, engineering, computation, mathematics, and collaboration use advance computing capabilities to understand and solve the most complex real life problems.
Diagnostic performance of cardiac magnetic resonance segmental myocardial strain for detecting microvascular obstruction and late gadolinium enhancement in patients presenting after a ST-elevation myocardial infarction
Authors: Gräni Christoph , Stark Anselm W. , Fischer Kady , Fürholz Monika , Wahl Andreas , Erne Sophie A. , Huber Adrian T. , Guensch Dominik P. , Vollenbroich René , Ruberti Andrea , Dobner Stephan , Heg Dik , Windecker Stephan , Lanz Jonas , Pilgrim Thomas
Published: July 2022

Background

Microvascular obstruction (MVO) and Late Gadolinium Enhancement (LGE) assessed in cardiac magnetic resonance (CMR) are associated with adverse outcome in patients with ST-elevation myocardial infarction (STEMI). Our aim was to analyze the diagnostic performance of segmental strain for the detection of MVO and LGE.

Methods

Patients with anterior STEMI, who underwent additional CMR were enrolled in this sub-study of the CARE-AMI trial. Using CMR feature tracking (FT) segmental circumferential peak strain (SCS) was measured and the diagnostic performance of SCS to discriminate MVO and LGE was assessed in a derivation and validation cohort.

Results

Forty-eight STEMI patients (62 ± 12 years old), 39 (81%) males, who underwent CMR (i.e., mean 3.0 ± 1.5 days) after primary percutaneous coronary intervention (PCI) were included. All patients presented with LGE and in 40 (83%) patients, MVO was additionally present. Segments in all patients were visually classified and 146 (19%) segments showed MVO (i.e., LGE+/MVO+), 308 (40%) segments showed LGE and no MVO (i.e., LGE+/MVO–), and 314 (41%) segments showed no LGE (i.e., LGE–). Diagnostic performance of SCS for detecting MVO segments (i.e., LGE+/MVO+ vs. LGE+/MVO–, and LGE–) showed an AUC = 0.764 and SCS cut-off value was –11.2%, resulting in a sensitivity of 78% and a specificity of 67% with a positive predictive value (PPV) of 30% and a negative predictive value (NPV) of 94% when tested in the validation group. For LGE segments (i.e., LGE+/MVO+ and LGE+/MVO– vs. LGE–) AUC = 0.848 and SCS with a cut-off value of –13.8% yielded to a sensitivity of 76%, specificity of 74%, PPV of 81%, and NPV of 70%.

Conclusion

Segmental strain in STEMI patients was associated with good diagnostic performance for detection of MVO+ segments and very good diagnostic performance of LGE+ segments. Segmental strain may be useful as a potential contrast-free surrogate marker to improve early risk stratification in patients after primary PCI.
Genotype-Specific ECG-Based Risk Stratification Approaches in Patients With Long-QT Syndrome
Authors: Rieder Marina , Kreifels Paul , Stuplich Judith , Ziupa David , Servatius Helge , Nicolai Luisa , Castiglione Alessandro , Zweier Christiane , Asatryan Babken , Odening Katja E.
Published: July 2022

Background

Congenital long-QT syndrome (LQTS) is a major cause of sudden cardiac death (SCD) in young individuals, calling for sophisticated risk assessment. Risk stratification, however, is challenging as the individual arrhythmic risk varies pronouncedly, even in individuals carrying the same variant.

Materials and Methods

In this study, we aimed to assess the association of different electrical parameters with the genotype and the symptoms in patients with LQTS. In addition to the heart-rate corrected QT interval (QTc), markers for regional electrical heterogeneity, such as QT dispersion (QTmax-QTmin in all ECG leads) and delta Tpeak/end (Tpeak/end V5 – Tpeak/end V2), were assessed in the 12-lead ECG at rest and during exercise testing.

Results

QTc at rest was significantly longer in symptomatic than asymptomatic patients with LQT2 (493.4 ms ± 46.5 ms vs. 419.5 ms ± 28.6 ms, p = 0.004), but surprisingly not associated with symptoms in LQT1. In contrast, post-exercise QTc (minute 4 of recovery) was significantly longer in symptomatic than asymptomatic patients with LQT1 (486.5 ms ± 7.0 ms vs. 463.3 ms ± 16.3 ms, p = 0.04), while no such difference was observed in patients with LQT2. Enhanced delta Tpeak/end and QT dispersion were only associated with symptoms in LQT1 (delta Tpeak/end 19.0 ms ± 18.1 ms vs. −4.0 ms ± 4.4 ms, p = 0.02; QT-dispersion: 54.3 ms ± 10.2 ms vs. 31.4 ms ± 10.4 ms, p = 0.01), but not in LQT2. Delta Tpeak/end was particularly discriminative after exercise, where all symptomatic patients with LQT1 had positive and all asymptomatic LQT1 patients had negative values (11.8 ± 7.9 ms vs. −7.5 ± 1.7 ms, p = 0.003).

Conclusion

Different electrical parameters can distinguish between symptomatic and asymptomatic patients in different genetic forms of LQTS. While the classical “QTc at rest” was only associated with symptoms in LQT2, post-exercise QTc helped distinguish between symptomatic and asymptomatic patients with LQT1. Enhanced regional electrical heterogeneity was only associated with symptoms in LQT1, but not in LQT2. Our findings indicate that genotype-specific risk stratification approaches based on electrical parameters could help to optimize risk assessment in LQTS.
The Prevalence of Activities of Daily Living Impairment in Patients With Heart Failure: A Systematic Review and Meta-Analysis
Authors: Lu Jing , Wang Meng , Zhang Yue , Mao Lifen , Chen Xiaoxiao , Yin Rulan , Shi Xiaoqing
Published: July 2022

Objectives

The prevalence of activities of daily living (ADL) in patients with heart failure (HF) reported in current studies were inconsistent, ranging from 11.1 to 70.5%. The purpose of this study is to quantify the prevalence of ADL impairment in HF patients.

Methods

PubMed, Embase, Cochrane, CINAHL, CNKI, SinoMed, VIP, and Wanfang databases were systematically searched for relevant studies (up to March 2, 2022). Cross-sectional, case-control, or cohort studies with detailed descriptions of overall ADL impairment in HF were included. Stata 16.0 was used for statistical analysis. Fixed-effect or random-effect model was adopted according to heterogeneity which was evaluated by Cochran’s Q and I2 values. Sensitivity analysis, subgroup analysis, and meta-regression were performed to investigate the sources of heterogeneity.

Results

A total of 12 studies with 15,795 HF patients were included in the meta-analysis, and the pooled prevalence of ADL impairment in patients with HF was 38.8% (95%CI: 28.2–49.3%; I2 = 99.5%, P < 0.001). No possible sources of heterogeneity were found in subgroup analysis and meta-regression. Funnel plots and Egger’s test showed no publication bias (P = 0.595).

Conclusion

The prevalence of ADL impairment is relatively high in HF patients. Differences in the prevalence of ADL impairment in patients with HF may be influenced by country, region, and assessment time. We suggest that more researchers could focus on the changes of ADL impairment in HF patients during different disease periods in different regions and countries.