bluuebunny/crossref_metadata_2025 huggingface dataset:
Análise da desinfecção apical do canal radicular preparado em três diferentes comprimentos de trabalho, utilizando movimento rotatório contínuo ou reciprocante e duas substâncias irrigadoras: estudo in vitro
Authors: LINS Rodrigo Pimentel , ARAÚJO Roberto Paulo Correia de , SILVA Sílvio José Albergaria da , REIS Joice Neves
Published: October 2019

Resumo Introdução O preparo do canal radicular, em especial o terço apical, é fundamental para o sucesso da terapia endodôntica, pois abriga o forame radicular, local que comunica o endodonto com os tecidos perirradiculares. Objetivo A presente pesquisa avaliou a contaminação do terço apical após a instrumentação de canais radiculares em três comprimentos distintos, através de dois tipos de instrumentação automatizada (rotatória contínua ou reciprocante) e uso de duas substâncias irrigadoras. Material e método Foram selecionados 66 pré-molares superiores birradiculares, os quais tiveram suas coroas removidas e raízes separadas, totalizando 132 corpos de prova (CPs). Na primeira fase, foram estabelecidos por sorteio seis grupos experimentais divididos de acordo com o comprimento de instrumentação (aquém, além e no forame radicular) e o tipo de instrumentação (rotatória contínua ou reciprocante), tendo como irrigante o hipoclorito de sódio. Na segunda fase, foi repetido o mesmo protocolo, utilizando-se como irrigante o cloreto de sódio. Para ratificar os resultados encontrados, foram criados dois grupos controles: positivo e negativo, cada um com seis CP. Resultado Não foram encontradas diferenças entre os grupos com instrumentação rotatória contínua ou reciprocante, nos seus diversos comprimentos de instrumentação, respeitando-se o mesmo irrigante. Os grupos irrigados com hipoclorito não apresentaram crescimento bacteriano, enquanto os irrigados com cloreto de sódio permaneceram contaminados após a instrumentação. Conclusão A ação mecânica dos instrumentos endodônticos sem o uso de substância irrigadora bactericida não promove a descontaminação apical do canal radicular e a escolha do tipo da cinemática dos instrumentos endodônticos (rotatória contínua ou reciprocante) não influencia significativamente a redução de bactérias no interior dos canais radiculares, bem como instrumentações que variam de um milímetro aquém até um milímetro além do forame também não apresentaram diferenças na redução de bactérias nesta pesquisa.
Políticas públicas de atenção à saúde do idoso: reflexão acerca da capacitação dos profissionais da saúde para o cuidado com o idoso
Authors: Martins Josiane de Jesus , Schier Jordelina , Erdmann Alacoque Lorenzini , Albuquerque Gelson Luiz de
Published: October 2019

RESUMO Este estudo tem o objetivo de refletir acerca do agir em saúde, a partir da articulação do Artigo 18 do Estatuto do Idoso com as atuais Políticas Públicas dirigidas à pessoa que envelhece em nosso país. Ressaltamos que o foco norteador da discussão centraliza-se na capacitação dos profissionais da saúde para o cuidado gerontogeriátrico. Tais profissionais são os responsáveis, direta e indiretamente, pela realização de um cuidado em saúde seguro, ético e com qualidade, sendo, portanto, agentes viabilizadores da efetivação das Políticas Públicas de Saúde dirigidas às pessoas idosas. É fundamental, também, o engajamento de toda a sociedade, com vistas à transformação da realidade dos idosos e humanização das relações entre viver e envelhecer. Assim, a reflexão sobre a questão do cuidado gerontogeriátrico, na perspectiva do Estatuto do Idoso, faz-se necessária na medida em que desvela perspectivas que se revestirão de cuidados seguros, éticos e com qualidade. Daí o grande desafio da equipe de saúde passa a ser a construção do cuidado integral, integrado e cidadão com a pessoa idosa; um novo modo de ser e agir em saúde vislumbrando a multidimensionalidade do ser que envelhece e do processo de envelhecimento humano.
THE BREAST RECONSTRUCTION PROCESS OF WOMEN WITH BREAST CANCER: A THEORETICAL MODEL
Authors: Volkmer Cilene , Santos Evanguelia Kotzias Atherino dos , Erdmann Alacoque Lorenzini , Sperandio Fabiana Flores , Santos José Luis Guedes dos , Souza Ana Izabel Jatobá de
Published: October 2019

ABSTRACT Objective: to build a theoretical model on the experience and meaning of the breast reconstruction process in women with breast cancer. Method: a qualitative research using Grounded Theory and Symbolic Interactionism as theoretical-methodological frameworks. Data collection and analysis occurred simultaneously, from April to October 2015, through theoretical sampling and theoretical saturation of the categories. Theoretical sample with 31 participants, 21 women and 10 health professionals, interviewed at home or at work, comprising four sample groups. Results: the theoretical model “Women face challenges and overcome difficulties: fear of death, breast mutilation and breast reconstruction, changing the way of being a woman” offers an explanation of the phenomenon and emerged from the systematic interrelation of the 11 study categories, with three causal categories, one category representing the context, five categories of intervening conditions, the strategies and the consequences represented by one category each. Conclusion: this study demonstrates the experience of the breast reconstruction process for women with breast cancer, the meaning of overcoming difficulties, value life and oneself, putting themselves first, taking care of themselves and learning to change, to be more tolerant, to value material things less and to face life with courage and faith. It also indicates that research on theoretical models on issues that plague our professional practices can enhance teaching and science and, consequently, improve care in women's health.
Turnip (Brassica Rapus L.): a natural health tonic
Authors: Javed Ahsan , Ahmad Awais , Nouman Muhammad , Hameed Adeela , Tahir Ali , Shabbir Umair
Published: October 2019

Abstract In addition to basic nutrition, plant-based foods provide substantial amounts of bioactive compounds which deliver desirable health benefits. During the last decade, secondary metabolites, also known as phytochemicals, obtained from plants, have aroused special attention by researchers. Amongst such plants, the turnip contains a few valuable components which not only endorse health benefits but also provide healing properties. Various bioactive components, for example peroxidase, kaempferol, phenolic compounds, sulforaphane, organic acids, vitamin K, glucosinolates etc are highlighted in this manuscript. Likewise, numerous minerals, such as copper, manganese and calcium, and organic acids, such as sinapic and ferulic acids and their derivatives, found in different amounts in fresh greens and turnip roots, are also discussed briefly. The current paper is focused on the phenolic compounds, which act as beneficial compounds for human health and can be isolated from plant foods, especially turnip. Due to the presence of bioactive constituents, turnip imparts a positive role with respect to the hepatic injury caused by diabetes, high antioxidant activity and a good hepatoprotective role. The impact of environmental conditions and processing mechanisms on the phenolic compound composition of Brassica vegetables, with special reference to turnip, was also briefly discussed.
Spatial and temporal distribution of Gymnorhamphichthys rondoni (Gymnotiformes: Rhamphichthyidae) in a long-term study of an Amazonian terra firme stream, Leticia - Colombia
Authors: Escamilla-Pinilla Carolina , Mojica José Iván , Molina Jorge
Published: October 2019

ABSTRACT Weakly electric fishes continually emit electric organ discharges (EOD) as a means of communication and localization of objects in their surroundings. Depending on water conductivity, the amplitude of the electric field generated is known to increase with decreases in electrical conductivity of the water. In Amazonian terra firme streams, water conductivity is extremely low and fluctuates constantly due to local and regional rains. In this context, the space between freely moving weakly electric fishes may be expected to decrease, on average, with an increase in water conductivity. To test this hypothesis, we recorded the positions at rest of the sand-dwelling fish Gymnorhamphichthys rondoni in a terra firme stream for several days in alternating months, over two years. Based on daily nearest neighbor distances among individual fish in a grid, we found a uniform temporal distribution pattern (which was not affected by water conductivity) indicative of site fidelity. Here we highlight the role of other factors that could influence resting site fidelity.
Conservation status and bio-ecology of Brycon orbignyanus (Characiformes: Bryconidae), an endemic fish species from the Paraná River basin (Brazil) threatened with extinction
Authors: Tonella Lívia Helena , Dias Rosa Maria , Vitorino Junior Oscar Barroso , Fugi Rosemara , Agostinho Angelo Antonio
Published: October 2019

ABSTRACT Brycon orbignyanus is an endemic species from La Plata basin whose stocks have been presenting significant reductions throughout the Paraná River. Brycon orbignyanus is categorized as an endangered species. This study evaluated aspects of the bio-ecology of this species that may be related to this threat, highlighting its distribution, abundance, and diet as well as the corresponding relationships between its recruitment and flood regimes. Data were obtained from different parts of the upper Paraná River (stretches free and regulated by dams) from 1986 to 2010 with more detailed data collected from the free remnant of this basin. The results indicate that no records for species exist at more than half of the sampling points located in dam-regulated sections of the Paraná River, whereas specimens were collected from 75% sites in the free plain remnant. We observed a remarkable effect of the hydrological regime on recruitment as well as distinct food demands during ontogenetic development, with adults almost exclusively consuming fruits and seeds, revealing that these individuals are supported by riparian vegetation. Thus, it is concluded that changes in the natural flood regime as well as riparian vegetation removal threaten B. orbignyanus populations in the Paraná River basin.
A new species of Astyanax (Characiformes: Characidae) from the rio de Contas basin, Bahia, Brazil
Authors: Zanata Angela Maria , Burger Rafael , Vita George , Camelier Priscila
Published: October 2019

ABSTRACT A new species of Astyanax from tributaries of the rio de Contas, Bahia, Brazil, is described. The new species differs from congeners by having three horizontal series of scales from lateral line to pelvic-fin origin and the distal margin of third infraorbital distinctly separated from vertical and horizontal limbs of preopercle, leaving a broad area not covered by superficial bones. The new species further differs from most congeners by the presence of bony hooks on all fins of mature males. Particularly from congeners occurring in rivers of the Northeastern Mata Atlântica freshwater ecoregion, it further differs by having the highest body depth just anterior to the dorsal-fin origin, 34-37 pored lateral line scales, a vertically elongated conspicuous dark humeral blotch reaching below the lateral line and a conspicuous dark wide midlateral stripe extending from the clear area on the rear of the humeral blotch to the end of middle caudal-fin rays and forming an inconspicuous blotch on caudal peduncle.
A morte em forma de poesia: comoção, indignação e reivindicação em cordéis midiatizados
Authors: Mendes Simone
Published: October 2019

Resumo Este artigo reflete parte das análises que vêm sendo desenvolvidas em nossa pesquisa de doutorado, cujo enfoque se constitui a partir da existência de uma dimensão argumentativa em cordéis que fazem interface com a mídia de informação. Em uma argumentação retórica, o raciocínio lógico e a demonstração não são suficientes para garantir a eficácia da interação, pois, ao basear-se na adesão do interlocutor a uma tese, através da crença, instauram-se outros pré-requisitos que devem ser observados, como o ethos do locutor ou a sua honestidade, sinceridade, senso de justiça, seriedade e confiabilidade; o pathos ou a capacidade do locutor de emocionar seu público através da comoção, da solidariedade, da indignação e da benevolência; e o lógos ou o próprio discurso e sua racionalidade, utilizado pelo locutor para reforçar seu ponto de vista e suas representações sociodiscursivas em torno do tema tratado. Ao analisarmos cordéis cuja temática gira em torno do homicídio, pudemos encontrar esse raciocínio teórico-metodológico.
Na rota dos festivais: uma tradição que se renova
Authors: Silva Andréa Betânia da
Published: October 2019

Resumo A oralidade é um espaço profícuo para o desenvolvimento de pesquisas e reflexões que busquem alterar, ou ao menos repensar, os alicerces teóricos que ora já não se apresentam tão firmes. Nessa esteira, o presente artigo volta-se para uma trajetória estabelecida na cantoria nordestina de improviso, mais especificamente no universo do repente, indo dos “pés de parede” aos festivais de violeiros que se espalham pelo Nordeste, visando perceber que contextos culturais propiciaram, se não a invenção, ao menos a renovação de uma tradição.
Recriar o espaço de voz do poeta: a memória entre dois mundos
Authors: Diniz Joseilda de Sousa
Published: October 2019

Resumo Poeta, cantador repentista, declamador, folheteiro, gravador que, após uma trágica enfermidade nas cordas vocais, torna-se pesquisador e escritor, José Alves Sobrinho foi um dos maiores poetas-cantadores nômades do Nordeste brasileiro. Seu nome está ligado ao período considerado a idade de ouro da cantoria e traz um testemunho privilegiado desse momento efervescente, marcado pela transição para as novas tecnologias da informação. Embrenhado nessa movência, na qual a palavra cantada perdia progressivamente espaço para a palavra impressa, José Alves soube, perspicazmente, recriar um espaço de diálogo entre a letra e a poesia. Acompanhando seu percurso artístico e intelectual, este estudo busca debruçarse sobre a capacidade criativa desse poeta e de seus pares, visando compreender a recriação das possibilidades necessárias à manutenção, difusão, adaptação e sobrevivência dessa arte.
Aids em cartazes: representações sobre sexualidade e prevenção da Aids nas campanhas de 1º de dezembro no Brasil (2013-2017)
Authors: Lermen Helena Salgueiro , Mora Claudia , Neves André Luiz Machado das , Azize Rogerio Lopes
Published: October 2019

Buscou-se analisar as representações da sexualidade e prevenção em cartazes produzidos pelo Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis (DCCI) a partir da diretriz da prevenção combinada (PC), adotada em 2013. Realizou-se análise de conteúdo, de caráter descritivo e documental, dos cartazes de campanhas do dia 1º de dezembro (2013-2017). Resultados apontam que aspectos relacionais do uso do preservativo teriam menos relevância, ao passo que a individualização do cuidado vem se acirrando sob a lógica de “testar para se conhecer”. Nota-se a oferta de alternativas de prevenção, por meio do símbolo do tripé “preservativo, teste e comprimido”, ou de novas tecnologias como a profilaxia pré-exposição (PrEP) e Profilaxia Pós Exposição (PEP). Isso sugere que, desde seu lançamento, a PC passou a orientar as campanhas do DCCI, em oposição a campanhas anteriores que privilegiavam populações-alvo e o preservativo masculino.
Sorafenib for Patients with Hepatocellular Carcinoma and Child-Pugh B Liver Cirrhosis: Lessons Learned from a Terminated Study
Authors: Labeur Tim A. , Achterbergh Roos , Takkenberg Bart , Van Delden Otto , Mathôt Ron , Klümpen Heinz-Josef
Published: October 2019

Lessons Learned

Recruitment of patients with advanced hepatocellular carcinoma and Child-Pugh B for sorafenib treatment and additional pharmacokinetic studies is challenging. Patients with Child-Pugh B liver cirrhosis have high rates of cirrhosis-related adverse events.

Background

Few data are available on the pharmacokinetics (PK) of sorafenib in patients with advanced hepatocellular carcinoma (HCC) and Child-Pugh B liver cirrhosis. This study aimed to explore the sorafenib PK and its relationship with efficacy and toxicity in these patients.

Methods

Patients with advanced HCC and Child-Pugh B7-8 liver function were prospectively recruited at a tertiary center. Adverse events (AEs), progression-free survival (PFS), and overall survival (OS) were recorded. Patients received a starting dose of 200 b.i.d. with toxicity-adjusted dose escalation to a target dose of 400 mg b.i.d. with PK sampling at fixed time points.

Results

Between May 2014 and March 2017, 12 patients were screened, of whom 7 progressed to a terminal stage during the screening (n = 6) or shortly after recruitment (n = 1). The five included patients had median PFS of 3.8 months (range, 1.7–10.8) and OS of 7.4 months (range, 1.7–25.8). Three patients had severe AEs and one patient had a partial response with an OS of 25.8 months. In 2017, the trial was aborted for lack of accrual.

Conclusion

Because of low accrual, no conclusion can be drawn on the sorafenib PK in patients with advanced HCC and Child-Pugh B liver cirrhosis. The poor survival and frequent cirrhosis-related AEs suggest limited benefit for most of these patients.
Türkiye Turizminin Tanıtılmasında Öncü Bir Süreli Yayın: Turizm Mecmuası (1957-1987)
Authors: AYDIN Çağdaş , AYDIN Ceren
Published: October 2019

Turizm Mecmuası, dünyada ve Türkiye’de turizm hareketinin hızlandığı bir dönemde yayımlanmıştır. Dergi 1957 yılından 1987 yılına kadar aralıksız bir biçimde 343 sayı olarak okuyucusuyla buluşmuştur. Derginin yayın amacı, Türkiye’nin sahip olduğu güzellikleri okuyuculara aktararak Türkiye’yi bir çekim noktası haline getirmek ve turizm hareketini topluma yaymak olarak ifade edilmiştir. Turizm Mecmuası dergisi devlet kurumları, özel yatırımcılar ve işletmeciler tarafından ilgiyle takip edilen süreli bir yayın olmuştur. Bu çalışmada, Türkiye’de turizmin gelişimine tanıklık eden ve 30 yıl boyunca kesintisiz bir biçimde yayımlanan turizm dergisini, turizm sektörüne ve turizm araştırmacılarına tanıtmak amaçlanmıştır. Bu amaçla derginin tüm sayıları araştırmacılar tarafından incelenmiş ve dergi içerik ve biçimsel olarak değerlendirilmeye tabi tutulmuştur. Bu noktada çalışmada, betimsel bir yaklaşım benimsemiş ve nitel araştırma yönteminden yararlanılmıştır. Yapılan incelemelerden sonra derginin biçimsel bir standart oluşturduğu ve bu standardını ilk sayısından son sayısına kadar koruduğu anlaşılmıştır. Diğer yandan dergi içerik olarak incelendiğinde, dergide dönemin turizmini etkileyecek olayların gündeme getirildiği, siyasi, askeri, ekonomik ve doğal afetler gibi birbirinden farklı tüm unsurların turizm açısından değerlendirildiği görülmüştür.
Basın-Yayın ve Turizm Bakanlığı Döneminde Turistik Tanıtım ve Propaganda Alanında Görülen Sorunlar (1957-1963)
Authors: EVCİN Erol
Published: October 2019

Türkiye turizm tarihi içinde önemli bir merhaleyi teşkil eden Basın-Yayın ve Turizm Bakanlığı (BYTB) döneminde (1957-1963) turizm alanındaki gelişmeleri tetikleyen ve kuvvetlendiren bir unsur olarak turistik tanıtım ve propaganda faaliyetleri önem arz etmiştir. Türkiye’nin tarihî ve doğal değerlerinin ülke insanına olduğu kadar yabancılara da tanıtılması, turistler nezdinde olumlu bir ülke imajı uyandırılması BYTB tarafından esaslı bir hedef olarak benimsenmiştir. Bununla birlikte ülkenin içinde bulunduğu siyasi, idari, iktisadi ve sosyal sorunlar, turizm altyapısının yeterli olmaması ve Batılı ülkelerin olumsuz yönde seyreden tarihî Türkiye algısı turizmin bütün alanlarını olduğu gibi tanıtma ve propaganda faaliyetlerini de olumsuz yönde etkilemiştir. Çalışma kapsamında, Türkiye turizminde önemli bir geçiş dönemini ve gelişim merhalesini teşkil eden BYTB döneminde turizmin tetikleyici unsurları arasında yer alan tanıtma ve propaganda faaliyetlerinde karşılaşılan sorunlar ele alınmıştır. Bu sorunların tespiti ve çözümü konusunda dile getirilen görüş ve öneriler, bu doğrultuda gerçekleştirilen faaliyetler Türkiye turizm tarihinin dönüm noktalarından biri olan BYTB döneminin anlaşılması açısından önem arz etmektedir.
Round Table 80th Anniversary of Victory at the Battles of Khalkhin-Gol, Organized by the Baikal Russian-Mongolian Resource Center
Authors: Anokhov Igor
Published: October 2019

The Baikal State University hosted a representative Russian-Mongolian scientific and educational forum organized by the Baikal Resource Center of Russian-Mongolian cooperation in the fields of education, science, youth policy and ecology affiliated with the Baikal State University.
State Analysis for Production and Trade of Boards and Plywood in the World
Authors: Karkhova Svetlana
Published: October 2019

Boards and plywood materials are a significant trade category in the global forest market. The demand and production of sheet and plate products are characterized by an intensive growth. Boards and plywood materials are widely used in construction, construction and repair works and in the furniture industry. The main representatives of the commodity group are veneer, plywood, particle boards and wood fiber boards. The article analyzes the production and consumption, export and import of these products by the world's regions and countries on a global scale. The leading countries in the world production and consumption by the types of the boards and plywood are identified. The article reveals the reasons affected the changes in the demand and supply of the boards and plywood materials in the past, it establishes that the factors influencing the production of the forest products are economic development of the countries of the world, new technologies and economic accessibility of the forest resources. The results of the study define the trends which will characterize the production and trade of the boards and plywood materials in the world, in the near and far future. Statistical data used in the article are obtained from the UN FAO database.
Batı-Dışı Modernleşme Kavramı Temelinde Türkiye’de Cumhuriyetin İlk Yıllarında Modernleşme Çabaları
Authors: ÖZÇELİK Tacettin Gökhan
Published: October 2019

Doğu ve Batı, Avrupa merkez alınarak kurgulanmış, gerçekte var olmayan, bütünüyle Avrupalının düşüncesinde doğmuş ve baskın kültür aracılığıyla dünyaya kabul ettirilmiş adlandırmalardır. Bu iki kutuplu yön anlayışı, yine bir üçüncüsü olmayan iki kültür ve uygarlığı ifade eder. Oryantalizm bu uygarlıklardan birini (Batı/Kuzey) ilerlemenin, sürekli gelişmenin, diğerini (Doğu/Güney) ise durağanlığın, geriliğin sembolü olarak bilimde, sanatta, kültürde, ekonomide vb. sürekli yeniden üretir. Bu yapılanma Batı’nın Aydınlanma felsefesi ışığında kurguladığı modern dünya görüşünü yansıtmaktadır. Modernleşmenin farklı toplumsal geleneklere sahip olan Batılı toplumlarda farklı kaynaklardan doğarak aynı modernlik temeline ulaştığı görülmektedir. Bu gerçekliğin sonucu olarak, modernliğin evrensellik ilkesinin sorgulanabileceği düşüncesinden hareket eden Batı-dışı modernlik düşünürleri, günümüzde halen modernleşme yolunda olan toplumların Batı’nın empoze ettiği kendisini taklit etmeyi öneren yolun, tek doğru yol olmayabileceğini, farklı izler üzerinden giderek de modernliğe ulaşılabileceğini iddia etmektedirler.
Research Team of the Academy of Mathematics and Systems Science of the Chinese Academy of Sciences Made Progress in Post-translational Modification of Protein v1
Authors: Ryan Steven
Published: October 2019

The protein whitening (P T M ) plays a fundamental role in the regulation of cell biosynthesis. P T M is an enzymatic covalent chemistry modification of the protein after translation of m R N A . Protein plastiding is very important because they potentially change the physical or chemical properties, composition, activity, cell localization or stability of the protein. In fact, the addition or removal of a chemical group at the N-terminus or C-terminus of an amino acid or protein can cause most of the protein to change. Some PTMcan be dynamically added or removed, which is a reversible protein function tuning mechanism. More than 400 specific egg white finishes have been identified, and more types of finishes are yet to be discovered (Creasy and Cottrell, 2004). To date, the most common PTMhas phosphoric acidification, threonization, ubiquitination, nitrosation, methylation, acetylation, sulfation, glycosylation analysisand acylation.
Caracterização da disfunção temporomandibular em estudantes da graduação de uma instituição de Ensino Superior de Alagoas
Authors: Oliveira Joyceane Alves de , Pedrosa Alexsandra de Souza , Coêlho Ana Candice , Silva Djanira Florentino , Panjwani Camila Maria Beder Ribeiro Girish
Published: October 2019

A ATM participa de papeis importantes do sistema estomatognático, sua desarmonia é tida disfunção. Temos por objetivo caracterizar a disfunção temporomandibular de estudantes de graduação de uma instituição de ensino superior de Alagoas. É um estudo discritivo, observacional, transversal e quantitativo, composto por alunos de IES, foram incluídos graduandos entre 18 e 29 anos, matriculados regularmente. Foram excluídos indivíduos com problemas de coluna, doenças reumatológicas ou qualquer outra condição que influencie na saúde das articulações. Instruídos a assinar o TCLE, responder o Questionário Anamnésico de Fonseca, e o Índice de disfunção clínica crânio mandibular (IDCCM) + índice de mobilidade mandibular – IMM. A análise estatística foi realizada pelo Teste do qui-quadrado e de Spearman com nível de significância de 95%. A amostra foi composta por 226 participantes, doa quais 76% eram do sexo feminino, 24% do masculino. 73,89% dos acadêmicos apresentou algum grau de DTM, onde 45,6% do tipo leve, 22,1% com DTM moderada e 6,2% severa. Fisioterapia e enfermagem apresentaram maior frequência, com uma porcentagem de 84,44% de DTM (p=0.000002504). A DTM não apresentou significância com mobilidade p=0,0957. 69% tinha diminuição da ADM, 39% tinham dor na região da ATM, 37% apresentou ruídos e 21% apresentou dor nos músculos mastigatórios. Mais de 70% da população estudada apresentou DTM, assim se propõe mais estudos que caracterizem a DTM, e tracem um perfil clínico dessa patologia, para implementar tratamento apropriado e que seja eficaz no público jovem, cada vez mais precocemente, a fim de diminuir sua incidência na vida adulta.
Atividade respiratória como teste de vigor em sementes de feijão (Phaseolus vulgaris L.)
Authors: Marques Rodrigues Caroline , Gonçalves Edilma Pereira , Silva Júlio César de Almeida , Viana Jeandson Silva , Lima Leandro Dias de , Almeida Débora Teresa da Rocha Gomes Ferreira de
Published: October 2019

Os testes rápidos de vigor são utilizados atualmente pelas empresas produtoras de sementes para avaliar a qualidade dos lotes. A indústria sementeira com a evolução tecnológica, exige cada vez mais rapidez na separação de lotes de alto vigor. Dessa forma, o trabalho objetivou verificar a eficiência e rapidez da atividade respiratória das sementes para diferenciar o vigor de lotes de sementes de feijão. O trabalho foi realizado na Universidade Rural de Pernambuco, conduzido no Laboratório de Análise de Sementes com três lotes de feijão adquiridos em municípios do estado de Pernambuco. Foram realizados alguns testes e determinações: teor de umidade, peso de mil sementes, germinação, primeira contagem da germinação, comprimentos e massa seca da parte aérea e raiz, condutividade elétrica, emergência de plântulas, comprimentos de parte aérea, raiz e massa seca da parte aérea. O índice de velocidade de emergência indicou o lote 3 e 1 como sendo os de maiores potencias fisiológicos e o lote 2 como o de menor. As sementes de feijão do lote 2, nos testes de germinação, índice de velocidade de germinação, índice de velocidade de emergência, massa seca de parte aérea e raiz como sendo o lote de menor vigor, e o que teve a menor liberação de CO2 no teste de atividade respiratória. O teste de atividade respiratória pode ser utilizado para determinar o vigor de sementes de feijão a partir de 12 horas de embebição.
The Canadian National Seismograph Network: Upgrade and Status
Authors: Bent Allison L. , Côté Timothy J. , Seywerd Henry C. J. , McCormack David A. , Coyle Kathryn A.
Published: October 2019

The Canadian National Seismograph Network (CNSN) operated by Natural Resources Canada consists of approximately 200 stations. Data from this network are used to produce the national earthquake catalog, to provide alerts in the aftermath of an earthquake, to develop the national seismic hazard maps, and for research within Canada and internationally. A significant upgrade to the instrumentation and infrastructure of the CNSN, which began in 2014, is nearing completion. The newly refurbished network is uniform in terms of instrumentation with the remaining single-component short-period stations converted to three-component broadband stations and consistent sampling rates across the network. Strong-motion instruments are now collocated with weak-motion instruments at many sites in all regions of Canada, and there is also a significant increase in the number of stand-alone strong-motion sites. Improvements in telecommunications were aimed at improving reliability and decreasing latency. All upgraded stations undergo a series of quality checks before the data are approved for dissemination. Data from the CNSN are freely available to the seismological community and the general public.
Efficiency of pharmacogenetic approach to anticoagulant therapy in patients with prosthetic heart valves
Authors: Gorbunova E. V. , Rozhnev V. V. , Ponasenko A. V. , Barbarash Olga Leonidovna
Published: October 2019

Background. This study examined clinical, demographic, anthropometric, and inheritance factors that influence individual sensitivity to warfarin therapy after heart valve surgery. The clinical significance of the pharmacogenetic approach was assessed using the individual time frame and time spent in the INR therapeutic range. Aims. We determined the clinical outcome of the pharmacogenetic approach at the start of warfarin therapy in patients with prosthetic heart valves. Materials and methods. The study included 915 patients, of which 512 women and 403 men (mean age 56±10 years), living in Western Siberia. Rheumatic heart disease was the main diagnosis that caused the acquired defect. Mechanical prostheses were used in 70% of cases of cardiac surgery. Real-time polymerase chain reaction used for molecular genetic testing. Results. The frequencies of the alleles and genotypes of CYP2C9 and VKORC1 in the study population of patients with heart valves prosthetic correspond to the distribution in Caucasoid populations. The use of pharmacogenetic testing results at the beginning of warfarin therapy reduced the time required for selecting a therapeutic dose of anticoagulant by 2 times and increased the duration of stay in the INR therapeutic range by 20.2%. Conclusion. The use of the pharmacogenetic approach at the begin‑ ning of warfarin therapy contributes to the effectiveness and safety of anticoagulant therapy in this category of patients.
Oral antifungal: the safety and efficacy of oral itraconazole in dermatophytosis
Authors: Thakare Vaishali , Patel Nandita K. , Patil Sharmila , Modi Navin
Published: October 2019

Background: The systemic antifungals like Griseofulvin, Itraconazole, Terbinafine, Ketoconazole and Fluconazole are widely used for superficial fungal infection. Hepatotoxicity with oral antifungals is well established fact. The rate of transient asymptomatic changes in liver function tests accounts for about 0.5 - 10% of all patients treated with systemic antifungals. Clinical hepatic toxicity is seen less frequently. The aim of this study is to evaluate the effect of oral Itraconazole on hepatic function and it’s efficacy in patients with extensive dermatophytosis.Methods: The total of 524 patients with extensive dermatophytosis were included in our study which was conducted in a tertiary care hospital in Navi Mumbai.Results: Itraconazole, a systemic antifungal agent is efficiently used in treatment of superficial and deep mycoses. It inhibits fungal cytochrome P450 dependent enzyme and thus impaires conversion of lanosterol to ergosterol. Adverse reactions to itraconazole includes drug reactions, gastrointestinal upset, headache, dizziness, thrombocytopenia, gynecomastia, reversible edema of extremities and metabolic side effects like hypokalemia, and hypertriglyceridemia. The level of hepatic transaminases increases in about 1%-5% of patients who have received continuous therapy with systemic itraconazole. Clinical hepatitis rarely occurs in patients and, recovery generally ensues with the cessation of medication.Conclusions: The baseline and post treatment liver function test is important to monitor if patient is on higher dose and longer duration of itraconazole therapy. The screening for high risk patients like poor liver function test, history of alcoholism, history of liver disease should be taken before stating the therapy.
Knowledge, attitude and practices towards medical research among resident doctors at a tertiary care hospital
Authors: Mandhare Rajshree N. , Khadke Venkatesh V. , Tamboli Saleem B.
Published: October 2019

Background: Research is a systematic process utilizing the scientific method for generating new knowledge that can be used to solve a problem or improving the existing status of a system. Human being is living a life of ease due to research in medical field. But it is important to know that whether those who are closest to society like resident doctors are involved in research process or not. Thus, the present study is planned to assess the knowledge, attitude and practice of resident doctors in a tertiary care hospital.Methods: This was the questionnaire-based study conducted among the resident doctors. Sample size calculated was 110 by open Epi software. A self-structured questionnaire was validated and distributed. Then we collected the data which was analysed using statistical analysis with MS excel and SPSS software version 21.Results: The 62% response rate was achieved. More than 50% of the resident doctors have the knowledge of p value and protocol writing. 63% students are strongly agreed that research in medical field is important while only 19% students are strongly disagreed that research increases burden over students 17% of the students have presented research paper. More than 75% student told that there are many barriers conducting research.Conclusions: This study demonstrates that more than 50% respondents have the basic knowledge about the medical research and they have the positive attitude too. But there is lack of the practices regarding research. Thus, there should be some efforts to improve practices of medical research among resident doctors.
Knowledge, attitude and practices about hemovigilance among practitioners: a cross-sectional study
Authors: . Roshi , Tandon Vishal R.
Published: October 2019

Abstract: Transfusion by blood and blood products forms an important part of treatment. But this is not free from transfusion reactions which may be in the form of fever, rashes, shivering, anaphylaxis or even death. Hemovigilance is a programme of reporting such events.Materials and Methods: The present study was conducted in a tertiary care hospital of Jammu, (J& K). Permission was taken from Institutional Ethics Committee, Govt. Medical College, Jammu. A pretested questionnaire was prepared and circulated among practitioners. They were given time of 15 minutes to fill that questionnaire. After 15 minutes, the filled questionnaire were collected and were analysed. The data was presented in tabulated form.Results: Total 50 practitioners were included in the study. All the practitioners had knowledge about transfusion reactions. Only 10% of the practitioners had knowledge that transfusion reactions can be prevented, 40% of the practitioners had knowledge about hemovigilance programme and had an idea that transfusion reactions can be reported. But only 10% of the practitioners knew where to report and who can report, 6% knew how to report. Only 48% of the practitioners thought that transfusion reactions should be reported, 70% of the practitioners thought that transfusion reactions can be dangerous. 40% of practitioners told that seminars/CMEs should be planned. 80% of practitioners had encountered transfusion reactions, but only 2% had documented the same. 10% of the practitioners had attended seminars, CMEs. Many reasons were quoted for not reporting transfusion reactions.Conclusion:  Overall, most of the practitioners have a positive attitude towards transfusion reaction reporting but knowledge regarding the haemovigilance concept is poor and the majority of them never reported such reaction. Hence, our study demands increased awareness and continued training to strengthen the haemovigilance system.
Topical ciprofloxacin induced ocular toxicity: case report
Authors: Deb Uttiya , Ray Soumya , Biswas Supreeti
Published: October 2019

Ciprofloxacin is a commonly used fluoroquinolone group of antimicrobial which is used for treating infective conditions like community acquired pneumonia and urinary tract infections. A patient of cataract was treated with ciprofloxacin eye drop as her pre-operative medication. She presented after four days with itching and redness in her right eye with swelling of the peri-orbital skin. We report this rare case where topical application of ciprofloxacin was responsible for the ocular symptoms.
The pattern of variations in the first trimester fetal heart rate in Indian population: a pilot study
Authors: R. Hethyshi
Published: October 2019

Background: Fetal heart rate is an indicator of fetal viability. During third trimester and labour the normal range of fetal heart rate is between 110-160 bpm as recommended by the international guidelines. Unlike this, the first trimester embryonic heart rate does not lie in the same range. During the first trimester the normal embryonic heart rate varies between each week of gestation, as determined by a few western studies. Indian studies on the same are not available. Objective of this study was to determine the trend of the fetal heart rate in first trimester of pregnancy in South Indian women.Methods: Transvaginal scan was done in 51 pregnant women with singleton pregnancy attending the antenatal clinic in a medical college hospital. Crown rump length and fetal heart rate were measured and plotted on a graph. Also, the fetal heart rate at different gestational age of our study was compared with the fetal heart rates at the same gestational age from the studies in the western population.Results: The range of fetal heart rate at different weeks of gestation was comparable to the heart rate variations as seen in the western population. The maximum heart rates at 9 weeks of gestation in our study was higher than the heart rate in the western population.Conclusions: Possibility of variation in the fetal heart rates in the first trimester in different populations cannot be ruled out until confirmed by studies with large sample size.
A comparative study of efficacy and safety of intramuscular carboprost and intravaginal misoprostol for cervical priming prior to first trimester surgical abortion
Authors: Mathuriya Gayatri , Verma Neha , Pandey Shivangi
Published: October 2019

Background: MTP Act no 34 of 1971 has been defined as Legal termination of pregnancy before the age of viability of fetus that is 20 weeks of gestation. There is a need to find a medical agent which can help in the process of abortion by speeding it up, with minimal side effects. The objective of this study was to compare the efficacy of I.M carboprost and intravaginal Misoprostol and to evaluate the safety profile of I.M carboprost and Intravaginal Misoprostol. To compare the cervical dilatation caused by I.M carboprost and intravaginal Misoprostol and to compare the blood loss and adverse effects of I.M carboprost and Intravaginal Misoprostol.Methods: Prospective randomized experimental study including pregnant women up to 12 weeks of gestation opting for M.T.P. Study conducted on 200 patients selected from patients admitted in MGM Medical College and M.Y. Hospital, Indore and Kalyanmal Hospital, Indore during the period July 2014 to March 2015. They were randomly divided into 2 groups. Group A who received intramuscular injection of 250 mcg of caboprost or Group B,which received 400 mcg of vaginal Misoprostol 4 hours prior to suction evacuation.Results: Intravaginal misoprostol achieves better cervical dilatation compared I.M carboprost which is statistically significant. Misoprostol is associated with higher blood loss as compared to I.M carboprost which is associated with nausea/vomiting & more likelihood of loose stools and abdominal cramps which is proved statistically.Conclusions: Intravaginal misoprostol is associated with higher blood loss as compared to I.M carboprost which is significant but intravaginal misoprostol achieves more cervical dilatation and causes less adverse events than I.M carboprost which is statistically more significant and therefore intravaginal misoprostol is the drug of choice for cervical priming prior to surgical abortion in terms of both efficacy and safety.
A prospective analysis of post mastoidectomy cavity complications
Authors: Rajan Dhanya , James Susan
Published: October 2019

Background: The main aims of surgical treatment of chronic middle ear suppuration are elimination of disease process, reconstruction of hearing mechanism and prevention of complications. The objective of this study is to find out the incidence of cavity problems after open cavity mastoidectomy. To evaluate perioperative factors involved in the causation of cavity problems.

Methods: A prospective analytical study was conducted among 78 patients came for open mastoidectomy admitted in department of ENT. Each patient had a follow up upto three months at twice weekly intervals. In this study a borderline healing period of three months (12 weeks) was given for the complete epithelialisation of an open mastoid cavity. SPSS was used for analysis.  

Results: The incidence of postoperative cavity problems in our set up is 26.92%. Youngest patient to undergo mastoidectomy was a 4-year-old boy. The youngest patient who presented with cavity problem was of 7years. 59 (75.64%) had sclerotic mastoid and 10 (12.82%) had cellular mastoid and 9 (11.53%) had diploeic mastoid. Hence out of the 21 postoperative mastoid cavity problems, 5 cases had large postoperative cavity, 18 cases had high facial ridge, 1 case had stenosis of meatoplasty, 17 cases had exposed middle ear and eustachian tube and 17 had postoperative granulations.

Conclusions: There should be complete exenteration of disease from the middle ear and mastoid. An adequately lowered facial ridge is an essential step to attain a dry cavity.
Sublingual dermoid cyst: a case report and review of literature
Authors: Dutta Angshuman , Vallur Srujan , Bothra Jitendra
Published: October 2019

Dermoid cysts in the floor of the mouth are relatively uncommon developmental lesions. They generally arise in the midline along the lines of embryonic fusion of the facial processes containing ectodermal tissue. We report a case of 24 year old lady with a Sublingual dermoid cyst which was surgically excised.
The benefit of Curcuma longa and Boswellia serrata to improve quality of life in osteoarthritis patients: a randomized controlled trial
Authors: Pinzon Rizaldy Taslim , Sanyasi Rosa De Lima Renita , Pramudita Esdras Ardi , Periska Septian Dewi
Published: October 2019

Background: Quality of life (QoL) can be affected by chronic pain in osteoarthritis (OA). Previous studies showed that combination of Curcuma longa (CL) and Boswellia serrata (BS) extract (CB extract) are promising for alternative treatment for pain in OA. This study aimed to measure the benefit of CB extract to improve QoL in patients with OA.

Methods: This was a randomized controlled trial (RCT) in OA patients. Subjects were randomized to 3 different group (Group 1: CB extract (350 mg of CL and 150 mg BS) and NSAID (400 mg ibuprofen or 50 mg diclofenac sodium); group 2: CB extract; group 3: NSAID). Each medication was taken two times per day for 4 weeks. QoL measured using 5Q-5D-5L that include five dimensiones in 5Q-5D: mobility, self-care, usual activities, pain/discomfort, anxiety/depression, with 5 levels of severity.

Results: There were 105 subjects at baseline. After 4 weeks of study, remained 95 subjects. The most common problem in group 1, 2, and 3 was pain (n=23, n=8, n=15 respectively). The improvement of level of severity in group 1 after 4 weeks of treatment was significant in mobility problems (p=0.002), pain/discomfort (p<0.001), and anxiety/depression (p=0.008). A significant improvement was only seen in usual activity problems (p=0.013) in group 2. The decrease of level of severity in usual activity problems (p=0.034), pain/discomfort (p=0.005), and anxiety/depression (p=0.018) in group 3 were also statistically significant.

Conclusions: CB extract was beneficial to improve QoL in OA patients with a less side effect compared to NSAID.
How to repair an immediately post-operative anterior cruciate ligament reconstruction failure? About a clinical case
Authors: Estves Joao , Rosa Joao Maia , Barros Luis , Ribau Ana , Pereira Paulo , Vilaça Adelio
Published: October 2019

We present a 23-year-old male with an early anterior cruciate ligament (ACL) reconstruction failure due to lateral wall blow-out, diagnosed on day one post-op. We were able to perform the revision using the original graft, and maintaining the initial tibial fixation, revising only the femoral fixation. At 1-year follow-up the patient is asymptomatic. In the early ACL reconstruction failures due to femoral wall blowout, it is possible to perform the revision surgery using the same graft and maintaining the same tibial fixation. This avoids de morbidity of a new graft harvest and the need for a new tibial tunnel.
History of Arrival and Development of Chinese Ethnic in Kupang
Authors: Taneo Melkisedek , Ndoen Fransina Aprilyse , Neolaka Stevridan Yantus
Published: October 2019

In the results of this study discusses the history of ethnic Chinese entry, the development and impact of the presence of ethnic Chinese in Kupang. This study uses historical research methods with steps that include heuristics, criticism to select historical sources, interpretation or steps to interpret the data that has been tested, then connect the facts in the form of concepts arranged based on an analysis of historical sources that have been obtained, and the last is historiography or the compilation of research results in written form or research report in accordance with the theme or problem under study.
Legal Standing of Work Order (SPK) by the Existence of Agreement on the Procurement of Public Goods in the Education Office of Padang City
Authors: Handayani Mira , Yuslim Yuslim , Ulfanora Ulfanora
Published: October 2019

Legal relation between user and provider, that occurs during the process of signing the agreement on the procurement of goods and services until the process of terminating the agreement, is called civil law relation which is specified as contractual relation. In the process of user and service user agreement, the government is represented by Budget User or Proxy or Commitment Officer (CO) or Procurement Official as an individual. Regarding this matter, the research problem is on how the legal standing of work order by the existence the public procurement agreement and on how the contractual relation between the Commitment Officer (CO) and the procurement of goods and services for the procurement of public goods at the Education Office of Padang City. This research employs empirical juridical approach. Based on the result of the research, it is found that the legal standing of work order, in addition to part of the contract, is also the decision of state administration in carrying out public authority in the form of procurement of goods and services which is violated through the state finance. In the meantime, the contractual relation of the parties is basically the same as the contract or agreement in general; the contract is binding on the parties such as laws in a lawful relationship and obligations.