bluuebunny/crossref_metadata_2025 huggingface dataset:
A Review of Immune Landscape of Clonal Hematopoiesis: Progression and Prospects for the Future
Authors: Ardestani Majid Teremmahi , Norouzian Marzieh
Published: August 2024

Context: Clonal hematopoiesis (CH), characterized by the clonal proliferation of mutant hematopoietic cells, is frequently observed in older individuals. It is widely recognized that ageing leads to somatic mutations in hematopoietic stem cells, increasing the risk of developing various diseases later in life. However, the impact of these clonal hematopoiesis-related mutations on the activation and regulation of the immune response remains uncertain. Evidence acquisition: To address this knowledge gap, a thorough review of the existing literature on clonal hematopoiesis and immune dysregulation was conducted. Relevant studies were systematically searched and their key findings were carefully analyzed to provide a comprehensive overview. Results: The review shows that mutations associated with clonal hematopoiesis have a significant impact on the modulation of immune responses in the body. These mutations are found to contribute to immune dysregulation, which has important implications for disease progression in the elderly. Conclusion: This review highlights the importance of studying immune dysregulation in the context of clonal hematopoiesis. By unravelling the relationship between CH-related mutations and immune responses, we can improve our understanding of disease progression in the elderly and identify promising therapeutic targets. This knowledge can inform the development of innovative interventions for improved disease management.
The Effect of Varicocelectomy on Sex Hormone Levels and Semen Parameters
Authors: Falahati Ali Mohammad , Mohajer-Bastami Mohammad , Natami Mohammad , Sobhani Alireza , Taqvaee Elahe , Latifi Masoomeh , Fallahi Soghra
Published: August 2024

Objectives: Varicocelectomy is a surgical intervention to treat varicocele. It may recover fertility in men by improving semen parameters and sex hormones. This research studied the role of varicocelectomy, focusing on semen properties and sex hormones. Methods: In this cross-sectional study, the data were collected from 45 patients with different varicocele grades who underwent varicocelectomy. The data were collected and compared before and after clinical examination. Results: After varicocelectomy, a significant improvement was observed in certain semen parameters, such as motility and concentration. However, among sex hormones, only testosterone increased after the surgical intervention (P=0.007). Discussion: To our knowledge, varicocele treatment may almost improve male fertility. Accordingly, varicocelectomy positively affects parameters such as testosterone and serum FSH levels and sperm count and motility. As such, varicocelectomy emerges as a practical approach to improve male fertility and sex disorders.
The Effect of the Acute Use of Different Doses of Glutamine Supplementation on Serum Testosterone and Cortisol Levels Following Exhaustive Exercise in Young Men
Authors: Naji Hamid , Sadeghi Abbas , Hematti Affif Ali , Ghiyami Seyed Hamed
Published: August 2024

Background: Anabolism has a major contribution in increasing proteolysis and muscle mass of athletes. This study was done to investigate the impact of the acute use of different doses of glutamine supplementation following exhaustive physical activity on cortisol and testosterone levels in young male athletes. Methods: Following a semi-experimental design, 24 male athletes with a mean age of 22.35±1.79 years were randomly selected and divided into two intervention groups (glutamine; 0.1 and 0.6 gr/kg body weight (BW) and a placebo group (10 g of dextrin dissolved in 500 mL water), each with eight subjects. Serum levels of cortisol and testosterone were measured immediately, 90 minutes, and 24 hours following the test. Data analysis was done using paired t-test and repeated measures analysis of variance at P<0.05. Results: Bruce protocol significantly increased cortisol levels immediately after physical activity (P<0.05). Cortisol levels significantly decreased in subjects receiving glutamine at 0.6 g/kg Bw (P=0.03) and 0.1 g/kg BW (P=0.02) 90 minutes and 24 hours following the protocol. Meanwhile, testosterone levels only increased in cases who received glutamine at 0.6 g/kg BW 24 hours following the protocol (P=0.02). Conclusion: According to the results of this study, taking a glutamine supplement at a dose of 0.6 g/kg body weight after exhausting activities is probably effective in maintaining an anabolic profile.
Investigating Patients’ Satisfaction With Patient-controlled Analgesia Versus Intrathecal Opioid Injection After Cesarean Section
Authors: Moallemy Abbas , Frahini Esfahany Farnoosh , Fekrat Fereydoon , Abdollazadeh Baghaei Alireza
Published: August 2024

Background: This study compares patients’ satisfaction with patient-controlled analgesia versus intrathecal opioid injection after cesarean section in Shariati and Khalij Fars hospitals in Bandar Abbas City, Iran, from 2016 to 2017. Methods: This double-blind, randomized clinical trial included 60 women with term pregnancies scheduled for elective cesarean section in Shariati and Khalij Fars hospitals in Bandar Abbas City, Iran, from 2017 to 2018. The patients were randomized into two groups: One group received patient-controlled analgesia (PCA), and the other group received intrathecal opioid injection. A numerical rating scale was used to assess pain and patient satisfaction. The patients also reported nausea, vomiting, and pruritus. The data were analyzed using the SPSS software, version 25. Results: Nausea and or vomiting did not differ significantly between the groups (P=0.46). The highest frequency of pruritus was observed in the PCA group at 1 (P=0.44), 4 (P=1.00), and 24 (P=0.24) h after surgery. Patient satisfaction was higher in the intrathecal opioid group (9.23±1.22) compared to the PCA group (8.84±1.22); however, the difference between groups was not statistically significant (P=0.08). Discussion: The results of the current study showed that despite the novelty of PCA, this method is not superior to conventional methods such as intrathecal opioid injection for pain relief. Also, patient satisfaction was lower with PCA compared to intrathecal opioids.
Achieving the Right to Health of Immigrants: Focusing on Intercultural Competence
Authors:   Catholic Institute of Bioethics, Oh Seung Min , Kim Pyeong Man
Published: August 2024

In the clinical field that provides health care services to immigrants, various medical ethics issues are raised, including discrimination, prejudice, hatred, lack of cultural sensitivity, and lack of understanding of various disease belief systems. The development of intercultural competence of health care workers to resolve this is an urgent task. Within a cultural background and context, care of patients from different cultures can be effectively and appropriately performed. Intercultural competencies of healthcare workers must continuously develop and strive for must be dealt with in various aspects of attitude, cognition, knowledge, and skill. Behavioral changes of health care workers must be brought about. Through this paper, we will examine the concepts, components, and intercultural competency process models, and examine the implications of strengthening the intercultural competence of health care workers for achieving right to health, a universal human right that migrants should have.
Pengaruh Pendidikan Kesehatan terhadap Pengetahuan dan Sikap Ibu tentang Pemberian Makan Bayi dan Anak Stunting
Authors: Hikmah Friska Nurul , Sunarsih Tri
Published: August 2024

Stunting is a chronic problem associated with lack of energy and generally appears from the first 1000 days of life. The peak of child growth and development occurs in the first two years of life, making the role of mothers important in ensuring adequate nutritional intake for their babies. The purpose of this study was to evaluate the Effect of Health Education on Mothers' Knowledge and Attitudes regarding Infant and Child Feeding (PMBA) stunting in Ngalang Village, Gunungkidul, Yogyakarta. The research method used a pre-experimental design with a one group pretest-posttest approach. The study population involved all mothers with stunted children in Ngalang Village, Gunungkidul, Yogyakarta as many as 85 respondents, with 46 respondents taken as samples using purposive sampling techniques. Statistical analysis was performed using the Paired Sample T-test. The results of the analysis found that the average education of junior high school mothers was 21 people (45.7%). Bivariate analysis showed a p value in the knowledge variable of 0.000 (<0.05), and in the attitude variable of 0.027 (<0.05). The conclusion of this study is that health education has a positive influence on mothers' knowledge and attitudes related to stunting PMBA. The suggestion for future researchers is to be able to use a diverse sample in geographical aspects such as family income, to ensure representative results.
Hubungan Pola Asuh Orang Tua terhadap Kejadian Diabetes pada Anak Usia Sekolah
Authors: Wenny Rahmawati  , Satiti Ika Arum Dewi
Published: August 2024

Elevated blood sugar levels are a sign of a metabolic disease called Diabetes Mellitus (DM). Several factors including the environment are contributors to the incidence of DM. The role of parents is mainly related to the child's lifestyle, including diet and food intake for the child. The lifestyle fostered in the family will affect the health of children. The purpose of this study was to analysis the parenting style of parents towards early diagnosis of diabetes based on blood glucose levels in children. A cross-sectional design and descriptive correlational design were used for this study. This study involved all students at SDN 2 Kepuharjo in August 2023 involving 92 children with total sampling technique. This study used the Parental Authority Questionaire instrument, which consists of twenty question items that assess how parenting is done. Details of the characteristics of the respondents were mostly 11 years old with 47 children (51.1%) and were in grades 5 and 6. The most respondents were female with 49 children (53.3%).  Working mother status was at 84 (91.3%).  53 children with less parenting (57.6%).  The results of the examination of blood sugar levels obtained were 17 children (18.5%) in the high category. Conclusion There is a correlation between parenting patterns and the number of cases of diabetes in school-age children in elementary schools with a p value of 0.006.
La lógica de la acreditación
Authors: Miroli Alejandro G.
Published: August 2024

El trabajo aborda el aporte del filósofo Henry Odera Oruka, en la noción de sistema de creencias de las naciones étnicas o comunidades originarias, incluidas en estados nación modernos, y como este aporte permite redefinir los supuestos ontológicos del problema de la acreditación de saberes y prácticas desde dicho Estado.   A partid de un juicio sobre costumbres funerarios en el cual Odera Oruka fue perito de parte, se caracterizan dos paradigmas ontológicos involucrados en dicho problema y se examina el impacto de las propuestas de Odera Oruka en la caracterización de estos paradigmas.
Derecho a la alimentación adecuada en Argentina. El Estado frente a su obligación de realizarlo.
Authors: Carrasco Maximiliano
Published: August 2024

El artículo presenta un resumen de la tesis de Doctorado titulada "Derecho a la alimentación adecuada en Argentina. El Estado frente a su obligación de realizarlo", autoría de Maximiliano Carrasco y que contó con la dirección de las Dras. Laura Pautassi y Pilar Arcidiácono.
Estudio sobre el nivel de conocimiento de salud bucodental en los alumnos de una universidad mexicana de Acapulco
Authors: García-Román Jennifer , Moreno-Pineda Ramón , Baldovinos-Leyva Irma
Published: August 2024

La salud oral es parte del bienestar general, mantener los dientes y las encías en buen estado es crucial para una vida saludable. Fomentar la higiene en una edad temprana y realizar visitas al dentista pueden garantizar una buena salud bucodental. Este estudio evaluó conocimientos sobre salud bucodental en adolescentes de segundo año de preparatoria, en edades de los 16 a 18 años, en la Universidad Hipócrates. Se utilizó una metodología descriptiva con enfoque cuantitativo, utilizando un cuestionario validado por 4 expertos en odontología de la universidad. El cuestionario abordó cinco dimensiones: datos demográficos (edad y sexo), frecuencia de visitas al dentista, conocimiento sobre alimentos que afectan la salud dental, uso de productos de higiene bucal y conocimientos generales sobre salud bucodental. El 51% de los adolescentes mostraron un conocimiento regular, evidenciando falta de conciencia sobre el cuidado adecuado de la higiene bucal, mientras tanto, el 26% mostró un conocimiento bueno, demostrando comprensión sobre cuidados odontológicos, reforzadas con visitas regulares al dentista, y el 23% restante registró un conocimiento deficiente, mostrando una falta de comprensión en el uso inadecuado de los productos de higiene bucal, especialmente en lo que respecta a los beneficios del flúor. Debido a que en general los aprendizajes no presentan niveles esperados, es crucial que la universidad intensifique sus esfuerzos en la educación sobre salud bucodental, especialmente enfocándose en mejorar la comprensión sobre el uso correcto de productos de higiene y la importancia de la nutrición adecuada para la salud dental.
Hubungan Dukungan Keluarga dengan Depresi pada Lansia di Desa Bentek Kabupaten Lombok Utara
Authors: Santriono Hadi , Hadi Suryatno , Ayu Mirah Adhi I Gusti , Ustiawaty Jumari , Mentari Ika Nurfajri
Published: August 2024

Proses kehidupan setiap manusia yang tidak dapat dihindari salah satunya adalah lanjut usia. Masalah pada orang dengan usia yang sudah lanjut adalah kurangnya beberapa kemampuan seperti menyesuaikan diri dengan perubahan dirinya secara psikologis. Oleh sebab itu, dapat memicu terjadinya gangguan mental, seperti depresi. Hasil studi awal pada Puskesmas Kecamatan Gangga yang menangani depresi lansia didapatkan jumlah lansia yang mengalami depresi di desa bentek kecamatan Gangga, Kabupaten Lombok Utara tahun 2019 sebanyak 61 orang yang tersebar di 18 Dusun dengan tujuan untuk mengetahui dukungan keluarga dengan depresi pada lansia di Desa Bentek Kecamatan Gangga. Populasi sekaligus sampel penelitian ini sebanyak 53 orang. Sampel didapatkan dengan menggunakan teknik sampel survey, sedangkan design penelitian yang digunakan adalah deskriptif korelasional dengan pendekatan cross sectional, instrumen penelitian menggunakan kuesioner dan analisis data menggunakan Korelasi Rank Spearman. Berdasarkan hasil analisis data bahwa parameter dukungan emosional termasuk kategori cukup (66,04%), dukungan informasi kategori cukup (67,92%), dukungan instrumental kategori cukup (62,26%), dukungan penghargaan kategori cukup (69,81%. Sedangkan depresi dengan parameter suasana hati termasuk kategori sedang (94,34%), parameter kehilangan kesenangan kategori sedang (69,81%), parameter kurang energi kategori sedang (73,58%), parameter perasaan bersalah kategori sedang (75,47%) dan parameter gangguan makan/tidur termasuk kategori sedang (94,34%). Sehingga dapat dikatakan bahwa ada hubungan antara dukungan emosional dengan depresi, dukungan informasi dengan depresi, dukungan instrumental dengan depresi, dukungan penghargaan dengan depresi lansia di Desa Bentek, Kecamatan Gangga, Kabupaten Lombok Utara. Saran dalam penelitian ini agar permasalahan depresi pada lanjut usia ditangani secara baik dan berkualitas.
Implementasi SNA dalam Menilai Popularitas Platform Pemesanan Makanan Online Berbasis Percakapan Twitter
Authors: Wibowo Adriyansyah Juri Setyo , Wibisono Setyawan
Published: August 2024

This research aims to understand the popularity of online food ordering platforms in Indonesia, although the data taken in Indonesian includes allied languages. This research combines the SWARA, WASPAS, and Social Network Analysis (SNA) approaches to achieve its objectives. The problem formulation proposed is how to measure and analyze the popularity of online food ordering platforms based on interaction data on Twitter social media. The SWARA method is used to determine the weight of the evaluation criteria, while WASPAS is applied to rank online food ordering platforms. Meanwhile, SNA is applied to analyze interaction patterns and user preferences for various online food ordering platforms. Twitter was chosen as the main data source because it provides direct conversation data and real depictions, allowing for in-depth and accurate analysis. Through Twitter, research can capture the dynamics of user interactions and how they communicate about various online food ordering platforms. This research aims to provide a strong foundation for decision makers in designing more effective marketing strategies and provide insight into the dynamics of competition in the online food ordering platform industry. The research results show that SNA-based analysis is able to clearly identify interaction patterns and user preferences.
PERFORMANCE EVALUATION USING THE DEA METHOD: A CASE STUDY OF ELECTRICITY COMPANIES IN INDONESIA
Authors: Putri Erni Puspanantasari , Purnama Jaka , Putra Bonifacius Raditya Sri Pramana , Puteri Agatha Hannabel Avnanta
Published: August 2024

Performance evaluation aims to continuously monitor the efficiency and economics of company operations and offers information for company decision-making. Adequate and comparable performance evaluation requires a method and measuring tool that can measure company performance in a complex manner. DEA is a method that allows the use of quantitative and qualitative characteristics. The State Electricity Company (PLN) is a company that focuses on the electric power sector for the benefit of society and the state. PLN's business sector consists of businesses such as: (i) production, transmission, and distribution of electric power; (ii) planning and development of electric power; (iii) exploitation and development of electric power; and (iv) business of services in the electricity sector. Indonesia's economic growth relies heavily on electricity. The aim of the research is to evaluate PLN's performance in Indonesia using the DEA method. DEA is a linear programming method that deals with performance measurement. Performance measurement consists of input and output parameters. Performance evaluation is one way to identify effective and ineffective DMU. In this way, PLN, as the driving force of the economy in Indonesia, can develop well in a sustainable manner. The research results indicated that efficient DMUs have a percentage of 94% and inefficient DMUs have a percentage of 6%.
Aprendizaje basado en proyectos para STEM. Breve manual práctico
Authors: Domenech Casal Jordi
Published: August 2024

A partir de experiencias llevadas al aula durante diez cursos académicos, el autor, profesor de secundaria con larga experiencia en este ámbito, explica en un tono franco y distendido ‒con anécdotas incluidas‒ cómo diseñar y aplicar proyectos basados en el aprendizaje basado en proyectos y en iniciativas STEM (ciencia, tecnología, ingeniería y matemáticas, por sus siglas en inglés). Un cíborg, medicamentos anticancerígenos, tres accidentes de tráfico, una misión espacial, el mapa de una casa, una constelación, un globo aerostático y un simulador de ecosistemas constituyen ochos proyectos ABP STEM aplicados en el aula, que se describen en profundidad, aportando la secuencia, los materiales de aula y las publicaciones relacionadas, junto con una valoración de su aplicación. A lo largo del texto, se usan marcos teóricos y su conexión con ejemplos para orientar el diseño de ABP a fin de que constituyan experiencias de aprendizaje rigurosas. Se abordan, asimismo, aspectos sobre la gestión y la organización del aula y la evaluación. Se proponen treinta apoyos (andamios didácticos) para desplegar el trabajo interdisciplinar entre las áreas STEM, en conexión con el desarrollo de destrezas STEM (pensamiento crítico, creatividad, pensamiento computacional, etc.) y distintos enfoques prácticos (controversias, datos remotos, sensores, tinkering, indagación, design thinking…). También se muestran logísticas de organización de centro (horarios, asignaturas…) para el despliegue ABP STEM en el centro educativo, incluyendo apoyos y orientaciones para el diseño y aplicación de planes de innovación. El libro culmina defendiendo una mirada crítica y escolar sobre el enfoque ABP STEM, así como sobre la conexión entre la teoría y la práctica educativa, invitando al rigor profesional y a la voluntad de servicio como guías para la innovación docente.
Knowledge and Practice of Safe Delivery among Community Health Practitioners in Bayelsa Central Senatorial District, Nigeria
Authors: David Odikeme E. , Kinigi Abraham Mercy , Uvoh Dr Solomon M , Abraham Lokobo J. , Emmanuel Dr Onokpite
Published: August 2024

Community health practitioners play a vital role in providing primary healthcare services, including antenatal/postnatal care and delivery. The research aim to identify safe normal delivery knowledge and practice among healthcare workers in primary healthcare clinics that plays significant role in the quality of care provided to pregnant women in their respective communities. Methods: A descriptive study design and a cluster sampling technique with the aid of questionnaires was used to select 210 community health practitioners from, Bayelsa Central Senatorial district. Results: From this study shows that 51.43% of respondents were within 25-34 years age bracket, 46.19% were married, 72.38% of respondents were CHEW’s, 53.81% were government employed and 92.38% were Christians while 1.90% and 5.71% were Islam and African traditional religion. An average knowledge of 94.76% community health practitioners on safe delivery was identified with a practice rate of 90.95% as well as 75.24% that has taken delivery successfully. Conclusion: Community health workers are known to be skilled birth attendants as well as positioned geographically and socially to deliver some aspects of MNH care. Hence we recommend that there should be an increased training and retraining of community health practitioners across Bayelsa state as this will help to protect life of women and their unborn /newborn babies.
Correlation of Gestational Age with Anterior-Posterior Thigh Diameter Measured by Two-Dimensional Sonography
Authors: Maruf Dr. Mohammed Abdoullah Al , Sultana Dr. Safia , Karim Dr. Ataul , Sultana Dr. Maria
Published: August 2024

Background: Anterior-posterior thigh diameter measurement via two-dimensional sonography (2D-US) correlates with fetal gestational age and reflects the growth and development of fetal thigh muscles and bones. This measurement, alongside estimated gestational age, offers valuable insights into fetal well-being and growth during pregnancy. This study aimed to evaluate the correlation of gestational age with anterior-posterior thigh diameter measured by two-dimensional sonography and estimated gestational age. Methods: This cross-sectional study was conducted at the Department of Radiology and Imaging, Mymensingh Medical College & Hospital, Mymensingh, Bangladesh from January 2010 to January 2012. As the study subjects, a total of 250 healthy women between the 24th and 38th weeks of normal pregnancy were enrolled by using a purposive sampling technique. For data analysis, SPSS version 23.0 was used. Results: The mean age of the participants was 24.79 ± 4.71 years with a range from 18 to 35 years. More than one-third (34.0%) of the women were in the age range of 21-25 years. The mean gestational age of all participants was 30.93 ± 4.32 weeks. Primigravida accounted for more than half (56.4%) of them. A statistically significant positive correlation was observed between fetal anterior-posterior thigh diameter and gestational age (p<0.001. Conclusion: There is a statistically significant positive correlation between fetal anterior-posterior thigh diameter and gestational age.
Hypertrophic Cardiomyopathy Unmasked: The Hidden Danger of Left Ventricular Apical Aneurysm through Coronary Embolization
Authors: Krimech A. , Jaafari M. , Sarsari M. , Abbi S. , Cherti Pr , Zarzur Pr , Amri Pr
Published: August 2024

Hypertrophic Cardiomyopathy (HCM) is a genetic heart disease characterized by left ventricular (LV) hypertrophy, with outcomes ranging from asymptomatic to sudden cardiac death (SCD). Accurate diagnosis and risk stratification are essential. This case report discusses a 52-year-old female with family history of sudden deaths, presenting with acute coronary syndrome symptoms. Investigations revealed atrial fibrillation, ST-elevation, and a thrombus in the left anterior descending artery (LAD). Echocardiography and cardiac CT confirmed a left ventricular apical aneurysm, multiple apical thrombus, and hypertrophic septal wall with systolic LV dysfunction. The report highlights the risk of thromboembolic events and SCD in patients with LV apical aneurysms. Meta-analyses and guidelines emphasize the importance of integrating risk markers like LV apical aneurysms and late gadolinium enhancement into clinical assessments. Given the patient’s family history, aneurysm, and LV dysfunction, primary SCD prevention with an implantable cardioverter-defibrillator (ICD) was deemed suitable. HCM patients with LV apical aneurysms represent a high-risk phenotype requiring comprehensive management, including SCD and stroke prevention.
Optimizing the Growth and Production of Pagoda Mustard Plants (Brassica narinosa L.) by providing Tofu Dregs Compost and Banana Peel Liquid Organic Fertilizer
Authors: Aji Pratama Nuranda , Ainy Dalimunthe Badrul , Ayu Putri Septyani Ika , Walida Hilwa
Published: August 2024

The pagoda mustard plant ( Brassica narinosa L.) is a type of vegetable that is healthy nutritious, and easy to cultivate because it is classified as an annual plant with a harvest age ranging from 40 to 45 HST. This research aims to optimize the growth and production of pagoda mustard greens ( Brassica narinosa L.) by providing Tofu Dregs Compost and Banana Peel POC. The location of this research was carried out in the appropriate home environment area in Danau Balai A Village, Rantau Selatan District, Labuhan Batu Regency, and the Agrotechnology Laboratory, Faculty of Science and Technology, Labuhan Batu University. Research I used the two-factor Randomized Group Plan (RAK) research method with three replications. ANOVA variance analysis (variety analysis) was used to test the observation data statistically. Duncan's Multiple Range Test (DMRT) was carried out at an α level of 0.05. The effect of giving banana peel POC and tofu dregs fertilizer in each treatment was not significantly different on the growth capacity of pagoda mustard plants. Based on the analysis of variance, POC treatment of banana peel waste had no significant effect on the number of pagoda mustard leaves aged 14 DAP, 21 DAP, and 28 DAP. POC treatment of Ambon banana peel waste had a significant effect on the number of pagoda mustard leaves at 35 HST and 42 HST.
Systematic approach in struggle against Heracleum Sosnowskyi with GPS mapping usage
Authors: Solomiichuk Mykhailo , Solomiichuk Maksym
Published: August 2024

Goal. Analysis of long-term data on the systematic control of Heracleum Sosnowskyi on the territory of the city of Chernivtsi and the city of Kovel, taking into account the effectiveness of the use of GPS mapping.
Methods. Researches conducted by visual method for identifying Heracleum Sosnowskyi in investigated regions. Used the quantity method used for determining sowing weediness. This method is based upon the weeds accounting on recording area. The spreading map formed with help of licensed software in studied districts. The device GPS-navigator used for (Garmin eTrex Legend) used for fixed points of Heracleum Sosnowskyi, areas of weeds’ hearths, spreading scopes and elimination areas, reference to coordinate system.
Results. Studies conducted as per operation maps. They had been developed upon the GPS mapping. They had been formed during 2016—2022 for previous areas Heracleum Sosnowskyi control. The patented way of struggle against Heracleum Sosnowskyi tested. The way based upon the biodestructor usage after cutting for plants drying and seeds material elimination. It may be used against young plants in chemicals in the form of a complex of herbicides are also. Monitoring of the territory of the city of Chernivtsi showed that as a result of the systematic destruction of Heracleum Sosnowskyi, 12 foci of weed disappeared. The plants’ density seriously decreased from 47.8 and 43.5 plants on 1 m2 to 1.1 and 0.2 plants on 1 m2.
Conclusions. Factual survey in town Chernivtsi showed that the systematic approach in struggle with Heracleum Sosnowskyi had allowed to decrease occupied area son 20 ha. The number of Heracleum Sosnowskyi plants decreased in more than 25 times. According to the results of systematic work in the city of Kovel, it is possible to claim the complete destruction of 2 outbreaks with a total area of 0.43 ha. GPS mapping usage allowed to increase monitoring and clear control for areas change of controlled object.
Diagnóstico e tratamento do câncer de colo de útero: uma revisão de literatura
Authors: Rodrigues de Queiroz Ronara , Wysllen Souza Avelino Karyllorranne , De Luca Castro Giovanna , Ruella Carvalho Daniela , De Andrade Lays , Alhandra Magno da Silva Laura , Pereira Gomes Franco Thais , Vidal de Souza Paula Maurício , Camargo de Oliveira Giovanna , Sales Lopes Cândido Ribeiro Victor Jorge , Félix Barbosa Maria Edite , Isabelle Alves Dantas Raissa
Published: August 2024

Este artigo tem por objetivo avaliar os aspectos clínicos do diagnóstico e do tratamento do câncer de colo de útero realizada nos últimos cinco anos. Revisão integrativa no banco de dados da BVS, LILACS, SciELO, PubMed de trabalhos publicados entre 2020 e 2024, combinando os descritores "câncer de colo de útero", "diagnóstico" e "tratamento" ao descritor booleano "AND". A incidência estimada de câncer do colo do útero no Brasil no ano de 2023 foi de 16.340 casos, e existem grandes diferenças regionais na incidência da doença. O fator de risco mais importante para o desenvolvimento deste câncer é a presença do vírus HPV com seus subtipos oncogênicos, além de outros fatores. Conclui-se que existem várias maneiras de rastrear o câncer de colo, mas o método ouro de diagnóstico do câncer de colo uterino é dado pela histologia, que pode ser realizada através de uma biopsia direta da lesão ou, em casos de lesão endocervical, através da conização de colo uterino ou curetagem do canal endocervical.
Manejo da pancreatite aguda: uma revisão de literatura
Authors: Grangeiro Matias Maria Beatriz , De Paulo Felix Jaqueline , Cortes de Aguiar Franco Leonardo , Fraga Pinheiro Nícolas , Costa Corgozinho Lucas , Briguenti Ramalho Rafaela , Brandão Malheiros Almeida Lizandra , Dias de Sousa Baobá Vivi , Santana Sakamoto Gustavo , Giselle Farias Fernandes Jaqueline , Melo dos Santos Neto Sileno , Bonamim Fiorilli Roberta
Published: August 2024

Este artigo tem por objetivo avaliar os aspectos clínicos da insuficiência cardíaca realizada nos últimos cinco anos. Revisão integrativa no banco de dados da BVS, LILACS, SciELO, PubMed de trabalhos publicados entre 2020 e 2024, combinando os descritores "pancreatite aguda", "diagnóstico" e "tratamento" ao descritor booleano "AND".  A pancreatite aguda é um processo inflamatório agudo decorrente da autodigestão do pâncreas causado pelas próprias enzimas pancreáticas, podendo ou não envolver subsequentemente outros tecidos regionais, órgãos ou tecidos a distância. Conclui-se que a presença de história clínica característica de pancreatite aguda associada ao aumento sérico das enzimas pancreáticas amilase e lipase confirmam o diagnóstico clínico-laboratorial. Os objetivos do tratamento da pancreatite aguda são o suporte clínico com reposição volêmica, analgesia, controle de náuseas/vômitos, realimentação precoce e fornecer suporte às complicações sistêmicas quando presentes
PERIIMPLANTITE: ETIOLOGIA E TRATAMENTO: REVISÃO DE LITERATURA
Authors: SOUZA DAIANE
Published: August 2024

O presente estudo possui como objetivo revisar criticamente a etiologia e os tratamentos da periimplantite. Realizou-se uma extensa revisão da literatura para identificar estudos relevantes acerca da proposta do presente estudo. Bases de dados eletrônicas, como PubMed, Scielo e Google Acadêmico, foram consultadas para obter o artigo publicado.Foram selecionados artigos que abordam diretamente os temas da inflamação dos tecidos periimplantares, envolvendo desde a mucosa até a perda de tecido ósseo ao redor do implante. Vários fatores estão envolvidos no desenvolvimento da periimplantite, como a presença de biofilme bacteriano, sobrecarga oclusal, doenças sistêmicas, alcoolismo e tabagismo, caracterizando a periimplantite como uma doença multifatorial. Existem, atualmente, variadas condutas terapêuticas para a periimplantite, como o tratamento mecânico, cirúrgico, medicamentoso (antibioticoterapia) e a laserterapia, sendo o caso clínico que irá determinar qual o tipo de conduta mais apropriada para o tratamento. O estudo reforça a importância da associação de técnicas, para os casos mais avançados da periimplantite, ressaltando, melhor que tratar a doença, prevenir ainda apresenta resultados mais seguros e consistentes, sendo importante educar o paciente dos cuidados necessários, após a reabilitação com implantes dentários.
O uso do Dupilumabe no tratamento da esofagite eosinofílica
Authors: Medeiros Myckanne , Barbalho Filho Eli Pinto , Holanda Guedes Ingrid , Do Rêgo Santos Joanna Amélia , Cordeiro de Almeida Guilherme Vitor , Da Conceição Sousa Christian Ricardo , Nunes Isaac de Santana , Augusta de Melo Katiane Fernanda , Menezes Heitor Keila Cristina , De Albuquerque Alves Natália de Fátima , Costa de Melo Kivia , Sobreira Nogueira de Almeida Suzay , Caruso Modesto Rafael
Published: August 2024

Introdução: A esofagite eosinofílica tem crescido nos últimos anos. Seus sintomas são incapacitantes e trazem prejuízos na qualidade de vida de seus portadores. O tratamento convencional falha em muitos casos. O imunobiológico dupilumabe se apresenta como alternativa no tratamento dessa doença, por meio do bloqueio da atividade da Interleucina  IL-4 e IL-13. Metodologia:  Realizou-se uma pesquisa bibliográfica nas plataformas Scielo, Biblioteca Virtual em Saúde e PubMed. No total, foram identificadas 1268 publicações, com os descritores “esofagite eosinofílica” e “dupilumabe”. Após avaliação metodológica, 22 publicações entre 2019 e 2024 em português, espanhol e inglês foram incluídas. Resultados e Discussão: O dupilumabe foi capaz de reduzir as contagens de eosinófilos esofágicos e melhorar significativamente a histologia do esôfago em todas as apresentações da doença. No tipo fibroestenótico, a medicação conseguiu a remissão eosinofílica em 100% dos casos estudados. Ademais, apresentou resultados excelentes quando utilizado no tratamento em portadores de outras patologias atópicas concomitantes. Em alguns estudos, foi visualizada a capacidade de melhoria da funcionalidade do esôfago. O alívio de sintomas foi registrado na maioria dos estudos, mas não houve unanimidade. Conclusão: O dupilumabe representa um importante aliado no tratamento da esofagite eosinofílica refratária à medicações de primeira linha. Entranto, seu alto custo e recente incorporação ao acervo terapêutico dessa doença constituem desafios a serem superados. É necessário realização de novos estudos, principalmente a longo prazo, sobre a eficácia da droga, dose e duração necessárias.
Aspectos Emergentes no Diagnóstico por Imagem da Gravidez Ectópica: Avanços Tecnológicos e Implicações
Authors: Ribeiro Victoria , Gonçalves Ribeiro Felicio Lucas Rayan , Rego Ramos Pereira Iaryma , Barbosa de Oliveira Roque Vinicius , Rigotti Maria Eduarda , Steffen Zilio Janaina Fernanda , Monteiro Martins Liz Kéthone , Dias Nery Marília Gabriela , Santiago lima verde neto Ari , Diniz Lins Luma , Rodrigues Alves Batista Beatryz , Machado Torquato Larissa
Published: August 2024

Este artigo visa explorar os aspectos emergentes no diagnóstico por imagem da gravidez ectópica, destacando os avanços tecnológicos recentes e suas implicações clínicas. Para a seleção dos artigos, foram utilizadas as bases de dados Scielo e Pubmed, com os termos de busca “Gravidez ectópica”, “Diagnóstico por imagem”, “Exame diagnóstico’’, combinados pelo operador booleano “AND”. Os resultados indicam que os avanços no diagnóstico por imagem têm melhorado significativamente a identificação da gravidez ectópica, através de alguns exames, como a ultrassonografia de alta definição, combinada com a quantificação sérica de β-HCG, a tomografia computadorizada, a ressonância magnética, e a inteligência artificial. Esses desenvolvimentos prometem melhorar continuamente a capacidade de detecção e o tratamento da gravidez ectópica.
BULIMIA NERVOSA: DO DIAGNÓSTICO AO TRATAMENTO
Authors: Dias Pedro César Veras , Júnior Francisco Almeida de Morais , Andrade Mariana Barboza de , Milhomem João Victor Braga , Queiroz Janaina Souza de Oliveira , Matos Cibelle Carriello , Junior Alfredo Nunes de Souza , Damasceno Larissa Silva , Vasconcelos Caroline Braga Palácio , Silva Dayna Ingrid Alves , Mecenas Dauana do Vale , Mascarenhas Caliza Calmon de Araújo
Published: August 2024

Apresenta-se uma revisão integrativa de literatura acerca da bulimia nervosa, seus aspectos clínicos, epidemiológicos, bem como o impacto dessa condição na vida do indivíduo. Essa condição caracteriza-se por um transtorno alimentar em que o indivíduo apresenta comportamentos periódicos de compulsão alimentar, nos quais o indivíduo ingere uma quantidade excepcional de calorias em um curto período. Tais episódios são sequenciados por comportamentos compensatórios, sentidos pela paciente como manifestações descontroladas e humilhantes. Utilizam-se critérios diagnósticos para definir o quadro, que pode coexistir com outras comorbidades. Há necessidade de uma equipe multidisciplinar para intervir na melhoria e na qualidade de vida dos pacientes, assim como um tratamento voltado para os vários aspectos que esse transtorno apresenta.
Importância da suplementação do ácido fólico e do ferro na gestação
Authors: Marques Ingrid Barabach , Teixeira Bruna Dacko , Goinski Luísa Emanoela Bandolin , Becchi Victor , Oliveira Ana Carolina kurquievicz de , Silva Michelle Bento Muniz , Ito Gabriel Issamu , Martins Manuella Fernandes , Taborda Gabrielle Camargo , Lunardon Olivir Macedo , Taborda Pedro Henrique Camargo , Batista Isabella de Vasconcelos Casal , Moreno Eduardo B. , Correa Giovanna Frankowski
Published: August 2024

Introdução: Durante a gravidez, a necessidade de suplementação do Ácido Fólico e do Ferro apresenta extrema importância, requerendo estratégias de manejo cuidadosas para preservar tanto a saúde materna quanto a fetal. Objetivo: Avaliar a importância e o impacto da carência dessa vitamina e desse micronutriente durante a gravidez e no futuro da prole. Metodologia: A coleta de dados foi conduzida por meio dos bancos de dados: Scientific Electronic Library Online (SCIELO), PubMed e Science Direct. Foram consultados diversos tipos de publicações, incluindo artigos científicos, monografias e revistas, com o objetivo de obter informações relevantes sobre o tema. Resultados e Discussão: A abordagem da utilização do folato e do ferro faz-se importante devido sua ajuda na saúde do recém nascido após diversos estudos. Dessa forma, as estratégias destacam a importância da individualização do plano de cuidados, para uma melhor saúde materna e fetal. Conclusão: Em conclusão a suplementação mostrou-se importante, embora exista desafios, seu benefício supera as desvantagens.
ICTS and e-Governance in Africa
Authors: Mncwango Noluthando , Mncwango Thando
Published: August 2024

Information and  Communication Systems (ICTs) have widely affected the world of governance which has led to a growth in e-governance in African countries. Public institutions have slowly adapted ICTs in order to achieve new levels of efficiency and more effective means of service delivery. These technologies continue to strengthen not only communication with society, but also further fosters the accountability and transparency of governments and government officials. A common dispute against ICTs in Africa is based on the knowledge that some African countries have a questionable ICT readiness due to weak infrastructure. For instance, Frans and Pather (2021:1) elaborate on the costliness of data in a country like South Africa which has easily led to numerous households having minimal access to the internet. Furthermore, due to high levels of poverty and rural areas in some African countries, many people do not have access to smartphones, nevertheless data or internet connection. However, in this time, the Covid-19 pandemic has accentuated the need to be 'in the know' for many people, which has thus led to a high demand for ICTs in countries (Frans and Pather, 2021:1). With the assistance and utilisation of secondary sources, this paper aims to highlight the benefits that come with incorporating ICTs in government as a mechanism to foster a relationship between government and its people. Through the consideration and incorporation of governance principles such as accountability, transparency, decision-making and participation, this paper will elaborate on how these principles can be achieved in African countries through the use of ICTs in governance. This research will further observe the following countries as case studies: Ghana, Rwanda, Egypt, Kenya and South Africa. The study  analyses these countries’ approaches in incorporating ICT and how it has benefitted them and will further benefit them. It will explore various aspects that determine a country's ICT readiness whilst further considering the risks, limitations and benefits that an incorporation of ICTs in governance brings.
Keywords: ICTs, Technology, Governance, Governments
HUBUNGAN TINGKAT PENGETAHUAN DAN MOTIVASI WANITA USIA SUBUR DENGAN PEMERIKSAAN INSPEKSI VISUAL ASAM ASETAT DI WILAYAH KERJA PUSKESMAS DELITUA
Authors: Hutabarat Vitrilina - , Sitepu Stefani Anastasia , Natalia Kristin , Hafiza Hilda Laila
Published: August 2024

Hutabarat, Vitrilina. The Relationship Between Knowledge Level and Motivation of Women of Childbearing Age with Acetic Acid Visual Inspection Examination in the Puskesmas Work Area. skripsi, Department of Midwifery, Faculty of Midwifery, Deli Husada Health Institute, Old Deli.
Based on a preliminary study conducted at the Deli Tua Health Center in 2023, there are 50 people who undergo IVA examination screening from a total of 100 women of childbearing age who visit the Deli Tua Health Center. The purpose of this study is to determine the relationship between the level of knowledge and motivation of WUS with IVA examination in the work area of the Old Deli Health Center. This type of research is an analytical survey with a cross sectional study design. The population is 100 women of childbearing age who visit the Deli Tua Health Center from January to June 2023. The sampling technique is 50 people. Data analysis using Chi-Square test with confidence level (α=0.05). There is a relationship between the level of knowledge and motivation of WUS with IVA examination in the working area of the Deli Tua Health Center in 2023 with a value of p=0.001 where p < α (0.05). Therefore, it is expected to be more active Women of childbearing age to increase Knowledge and Motivation carried out by Health workers and Women of childbearing age are expected to seek information about cervical health and early detection of cervical cancer in mass and print media.
a PEWARNA ALAMI AKAR MENGKUDU (Morinda citrifolia L) SEBAGAI PENGGANTI SAFRANIN PADA PEWARNAAN GRAM NEGATIF
Authors: Sari Sofiani
Published: August 2024

Noni is a plant that has the potential to be used as a therapeutic element, but many people are still unaware of its benefits. This plant is one of the herbal plants part of the noni plant has body parts that can almost all be utilised. Noni root or known as Morinda citrifolia L. can be processed and used as a natural dye because it contains morindon. Noni contains the molecule morindin, a disaccharide derivative of anthraquinone or anthraquinone, so its roots are used as a dye. Morindon is a natural dye produced when morindin glycoside is hydrolysed which will produce a red colour. Morinda citrifolia Linn fruit has antibacterial properties inherent in phenol and flavonoid molecules. The purpose of this study is to determine whether or not noni root extract can be used as an alternative to safranin gram staining. The variables used were noni root extract and gram staining which were carried out by Experimental Laboratories. This research began in May to June 2023. The results showed that noni root extract in a 60-second soak could colour gram-negative bacteria but in 20-second and 30-second soaks there was no red colour on gram-negative bacteria. Noni root extract can be applied as an alternative gram stain to safranin.
PERSONAL HYGINIE PADA SISTEM REPRODUKSI PADA SISTEM REMAJA DI DESA SELAMAT DUSUN IV KECEMATAN SIBIRU BIRU
Authors: Krisna Putri , Sari Husna , Purba Tetty Junita , Yanti Mutiara Dwi , Siregar GF Gustina
Published: August 2024

Pengetahuan tentang Kesehatan reproduksi merupakan faktor penting dalam menentukan perilaku hygiene pada perempuan. Untuk itu, pengetahuan tentang kesehatan alat reproduksi sebaiknya diajarkan saat perempuan ada di bangku sekolah agar para remaja putri memiliki pengetahuan tentang kesehatan reproduksi dan nantinya memiliki perilaku yang tepat dalam hyginitas. Metode : Desain penelitian yang digunakan adalah analitik crossectional. Sampel dalam penelitian ini sebanyak 41 responden yang ditentukan berdasarkan kriteria penelitian. Penelitian ini dilakukan di MA Model Zainul Hasan Genggong Probolinggo. Instrumen pengumpulan data menggunakan lembar kuesioner. Analisa data dilakukan menggunakan uji Kendal’s tau b. Hasil : Dari hasil uji analisa secara komputerisasi dengan program SPSS For Windows 17.00 menggunakan uji Kendal’s tau b didapatkan ρ = 0,00 dan α= 0,05 yang artinya ρ < α, sehingga hipotesis penelitian diterima yang berarti terdapat hubungan antara tingkat pengetahuan tentang kesehatan alat reproduksi dengan perilaku personal hygiene saat menstruasi pada remaja putri di MA Model Zainul Hasan Genggong. Kesimpulan : Dalam meningkatkan pengetahuan remaja putri tentang alat Kesehatan reproduksi dibutuhkan peran aktif dari semua pihak untuk dapat melakukan kolaborasi dan secara kontinu untuk melakukan sosialisasi terkait alat reproduksi pada remaja putri
Algebraic Structures and Their Applications in Modern Cryptography
Authors: Annu
Published: August 2024

Modern cryptography relies heavily on the principles of algebraic structures to ensure the security and integrity of data. This paper explores the fundamental algebraic structures that underpin contemporary cryptographic systems, including groups, rings, fields, and lattices. We provide a detailed examination of how these structures are employed in various cryptographic algorithms and protocols, such as public-key cryptography, digital signatures, and hash functions. an overview of basic algebraic concepts and their properties, followed by an in-depth analysis of their applications in cryptographic schemes. For instance, the use of elliptic curve groups in Elliptic Curve Cryptography (ECC) offers enhanced security with smaller key sizes compared to traditional systems like RSA. Similarly, lattice-based cryptography presents promising solutions for post-quantum security, leveraging the hardness of lattice problems to resist attacks by quantum computers. the role of algebraic structures in the development of advanced cryptographic techniques, such as homomorphic encryption, which allows computations on encrypted data without decryption, and zero-knowledge proofs, which enable the verification of information without revealing the information itself. Through these examples, we illustrate the critical importance of algebraic structures in achieving robust and efficient cryptographic systems.