bluuebunny/crossref_metadata_2025 huggingface dataset:
A RARE HEMATOLOGICAL MANIFESTATION OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA(PNH) WITH PANCYTOPENIA IN A YOUNG MALE PATIENT
Authors: Chauhan Sachin , Pankajkumar Trivedi Dhvani , Pankajkumar Trivedi Rudra , M Shah Hemantkumar
Published: February 2025

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder that can cause severe complications like hemolytic anemia, bone marrow
failure, and blood clots.¹ It occurs due to a mutation in the PIG-Agene,on chromosome Xp22.1, leading to the absence of protective proteins CD55
and CD59 on red blood cells.³ Without these proteins, the cells are vulnerable to the body's complement-mediated lysis. We encountered a 25-yearold man who presented with nasal, gum, and rectal bleeding, fatigue, breathlessness, and fever. His blood tests revealed severe pancytopenia, and a
bone marrow biopsy showed aplasia. Flow cytometry confirmed CD55 deficiency, diagnosing him with PNH. He was treated with blood and
platelet transfusions and antibiotics, and his condition improved. He was advised to consider a bone marrow transplant for long-term management.
Apart from causing anemia and other symptoms, PNH can also cause life-threatening blood clots due to free hemoglobin disrupting nitric oxide
levels, leading to vessel damage,making venous thrombosis a major cause of death. Treatment often includes eculizumab, which reduces
hemolysis and clot risks, but it is costly and less effective in severe bone marrow failure.⁷ In such cases, stem cell transplantation is the only curative
option. Early diagnosis in patients with unexplained anemia or pancytopenia is essential for timely and effective treatment.
ROLE OF LASER, PRP IN ADJUNCT WITH CHLORHEXIDINE IN ROOT CANAL DISINFECTION AGAINST PATHOGENIC MICROORGANISMS – A NEW SPHERE IN ENDODONTIC THERAPY
Authors: Paliwal Pragyan , Gupta Swati , Singh Aditi , Singh Gitanjali
Published: February 2025

The objective of endodontic treatment is to eradicate all the microorganisms and microbial outcomes from root canal system. This aim can be
reached through proper chemical and biomechanical debridement of root canals of the particular infected teeth. This review article narrates the
distinct requirements of the agents with the specific antimicrobial efficacy. Sodium hypochlorite is the primary irrigant by virtue of its organic
tissue dissolution capacity and broad antimicrobial properties. EDTA, chelating agents are recommended as additional solutions to remove the
smear layer and to hinder its formation on dentin surface.. This article reviews the new agents which can be used in future endodontic treatment with
good antimicrobial efficacy and no side effects.
STUDY ON THE PATIENTS PERCEPTION OF ORTHODONTIC TREATMENT IN CENTRAL TRAVANCORE POPULATION- A QUESTIONNAIRE BASED STUDY.
Authors: Daniel Jibin Joy , G Geojan Don , James Arpith
Published: February 2025

Introduction- Malocclusion is a common phenomenon which can affect the physical, social, psychological and sometimes economical well-being
of the patients. Orthodontics is that branch of dentistry deals with facial growth, development of the dentition and occlusion together with the
prevention and correction of occlusal anomalies. This questionnaire study aimed to assess the overall frequencies of positive perception towards
orthodontic treatment categorized according to age, sex, and area of living, and to identify barriers or negative perceptions preventing them from
receiving orthodontic treatment. A google form for the questionnaire-based study on patient's percep Materials And Methods- tion for orthodontic
treatment was created. The questionnaire included 8 questions, that assessed the demographics; age, sex, and general information about the
orthodontic treatment and treatment duration. The questionnaire was circulated through various social media platforms, to be filled by participants
who came to OPD of Department of Orthodontics in various hospitals and colleges in Central Travancore, as well as other private dental clinics for
those who had a query about orthodontic treatment. The study revealed that aesthetics was the main c Results- oncern for getting orthodontic
treatment whereas functional concern was less frequently reported. Patient believed that the treatment could make them more beautiful and
confident. This survey-based questionnaire helped in assessing the patient perception and attitude to Conclusion: wards Orthodontic treatment.
Aesthetic was the major issue for seeking orthodontic treatment, and also motivating factor for the start of treatment. Cost and duration of the
treatment were major barrier for the start of the orthodontic treatment.
ATYPICAL PRESENTATION OF DISSEMINATED NEUROCYSTICERCOSIS : LARGE CYSTIC CAVITY IN PONS
Authors: Rathod Hriday , Gandhi Pankaj
Published: February 2025

NCC is most common parasitic infection of central nervous system. Human acquired cysticercosis by ingestion of food contaminated with ova of
Taenia Solium. There are mainly two types of Neurocysticercosis : Parenchymal Neurocysticercosis in which brain tissue is involve;
Extraparenchymal Neurocysticercosis which occur outside brain tissue like ventricles or Subarachnoid space. Other locations like Spinal cord
(intra or extramedullary), Eye and Skeleton muscle can also be involved in Cysticercosis. In our case its location in Pons is rare and its large size
also so we have reported this case.
ROLE OF PREOPERATIVE INJECTION BETA-HCG IN OPEN ORCHIOPEXY FOR INTRAPERITONEAL UNDESCENDED TESTES – AN EXPERIENCE OF FIVE CASES FROM PERIPHERAL TERTIARY HEALTHCENTRE WITH REVIEW OF LITERATURE
Authors: Kushwaha Renu , Kushwaha Santosh , Upadhyay Prashant
Published: February 2025

Introduction: Cryptorchidism, or undescended testes (UDT) is defined as the failure of normal descent of the one or both testis into the scrotum. It
is one of the most common congenital anomalies in male infants, with an estimated incidence of 1–3% in full-term neonates and up to 30% in
preterm infants. Among these, 20–30% of cases involve non-palpable testes, which can be located intra-abdominally, inguinally, or absent
altogether. [1] A normal functioning hypothalamic-pituitary-testicular (HPT) axis is essential for the testicular descend. [2] About 70% of UDT
descend spontaneously till 1 year of age, especially before 3 months age, after which spontaneous descend is highly unlikely.[3] The management
of non-palpable testes is essential to prevent complications such as infertility, testicular atrophy, testicular torsion, malignancy.[1,4] Human
chorionic gonadotropin (hCG), a hormone that mimics the luteinizing hormone (LH), has been proposed as a therapeutic option to stimulate
testicular descent in cases of cryptorchidism. Beta-hCG injections are used to trigger testosterone production in Leydig cells, potentially
facilitating testicular descent especially in low lying testis in the inguinal canal or close to it. However, the efficacy of this approach, particularly in
cases of intraperitoneal non-palpable testes, remains controversial, with success rates varying widely across studies. [5,6] Laparoscopic
orchiopexy remains the standard treatment for non-palpable testes, hormonal therapy can be used as an adjunct to the open orchiopexy in selected
cases of palpable UDT, lying close to the deep inguinal ring (DIR), especially in resource limited peripheral settings where, laparoscopic
procedures are not possible due to unavailability of instruments and expertise. This case series aims to evaluate the role of Beta-hCG injection as an
adjunct in the management of intraperitoneal undescended testes mostly at or around the DIR enhancing the efficacy, safety, and providing insights
into optimizing open orchiopexy procedure in the resource limited rural settings.
NON-URGENT VISITS TO THE EMERGENCY DEPARTMENT AT SVIMS, TIRUPATI: A RETROSPECTIVE OBSERVATIONAL STUDY
Authors: Babu S Prakash , Mohmmad Ashik , Gupta Rohith , Reddy Krishna Simha
Published: February 2025

Background: Non-urgent visits to emergency departments (EDs) can contribute to resource strain and decreased efficiency in delivering care to
critical patients. This study aimed to evaluate the proportion, characteristics, and temporal trends of non-urgent ED visits at Sri Venkateswara
Institute of Medical Sciences (SVIMS), Tirupati. Methods: A retrospective observational study was conducted using data from patients visiting
the ED over a one-month period. Patient demographics, presenting complaints, triage categories, and visit timings were analyzed. Non-urgent
visits were defined as those classified under Triage Categories 3 (Non-Urgent) and 4 (Routine). Statistical tests, including Chi-square and ANOVA,
were used to assess associations and differences in the data. Results: Out of 700 ED visits, 500 (71.43%) were non-urgent. The most common
presenting complaints among non-urgent cases were chest pain (23%), abdominal pain (18%), and breathing difficulty (15%). Middle-aged
individuals (31–50 years) and males constituted the majority of non-urgent visits. Visits peaked during morning hours (50%) and on weekdays,
particularly Tuesdays (24%). Statistically significant associations were found between presenting complaints and age groups (p=0.02p =
0.02p=0.02). Conclusion: The high proportion of non-urgent ED visits highlights the need for public education on appropriate healthcare settings
and the enhancement of outpatient services. Temporal trends and demographic patterns can inform targeted interventions to optimize ED
utilization.
PARANASAL OSTEOMA: A CASE REPORT
Authors: Chawla Somya , Landge Sonali , Deshmukh Sunil , Keche Prashant , Nikam Shailesh
Published: February 2025

Paranasal sinus osteomas are the most common benign fibro-osseous lesions that occur in the paranasal sinuses, having potential serious
complications.2 With a prevalence ratio of 2:1 towards males, in 95% of the cases, the osteomas are situated most commonly in the frontoethmoidal
region. However, osteomas of the maxillary sinus account for less than 5% of cases. The management of symptomatic paranasal sinus osteomas is
surgical and is decided based on tumor size and location, patient symptoms, and experience of the surgeon. We report on a 40-year-old male patient
presenting with a giant calcified mass. In this case, an endonasal approach with caldwell luc approach was the most appropriate management with
the large size of the tumor. No recurrence at 24 months follow-up was reported.
ECTOPIC PREGNANCY: INCIDENCE, RISK FACTORS, AND OUTCOMES IN A TERTIARY CARE CENTER – A PROSPECTIVE OBSERVATIONAL STUDY
Authors: Das Debasish , Das Debasree , Choudhury Subrata
Published: February 2025

Background: Ectopic pregnancy (EP) is a life-threatening condition that occurs when a fertilized ovum implants outside the uterine cavity.
Despite advancements in diagnostic and therapeutic modalities, EP remains a significant cause of maternal morbidity and mortality worldwide.
Methodology: This prospective observational study aimed to investigate the incidence, risk factors, clinical presentations, and outcomes of
ectopic pregnancies in a tertiary care center. Conducted at the Department of Obstetrics and Gynaecology, AIIMS, Rishikesh, the study included 66
cases diagnosed between January 2019 and June 2020. Key risk factors included prior caesarean sectio Results: ns, abortions, and contraception
use. Most cases presented with amenorrhea (92.42%), abdominal pain (87.8%), and vaginal bleeding (74.2%). Surgical management was
predominant (72.72%), with salpingectomy being the most common procedure (87.7%). Medical management with methotrexate was successful
in select cases (24.24%), and expectant management was rarely employed. This study underscores the i Conclusion: mportance of early diagnosis
and intervention to improve maternal outcomes. Strengthening diagnostic capabilities, especially at primary care levels, and ensuring timely
referral can significantly reduce the incidence of ruptured ectopic pregnancies.
UNMASKING THE COMPLEXITIES BY TAILORING AYURVEDIC INTERVENTION IN A RARE CONDITION “ THE FRIEDREICH'S ATAXIA” – A CASE REPORT
Authors: Gayathri J. , Kumar Moharana Pradeep , Rout Suvendu
Published: February 2025

Background: Friedreich ataxia (FA) is the most common hereditary ataxia accounting for approximately 50% of all ataxia cases. 75% in patients
less than 25 years of age. The prevalence of FA globally is 1 in 40,000. It frequently occurs in Europe, the Middle East, South Asia, and North
, Africa . Methods: This report discusses a case of a 23-year-old male, previously healthy, presented with a 1-year history of progressive gait
instability and frequent falls. The patient also experienced numbness and tingling sensation in the extremities with a Family history was treated
with panchakarma procedures like Rukshana Chikitsa followed by Brihmana chikitsa along with Oral medications. Result: After 3 sittings there
was some relief in symptoms. Conclusion:The present case of FAis managed with the treatment principle of Kaphavruta vata.
A DOUBLE-BLIND RANDOMIZED CONTROL TRIAL TO COMPARE POSTOPERATIVE ANALGESIA WITH EPIDURAL BUPIVACAINE 0.25% AND ROPIVACAINE 0.2% IN LUMBAR SPINE SURGERY
Authors: Rajesh Venishetty , Keniya Varshali
Published: February 2025

Background: Postoperative pain after spinal surgery delays mobility and discharge from hospital. Bupivacaine and ropivacaine have similar
nerve-blocking effects but differ in their impact on motor function. The study aimed to compare these two drugs for epidural analgesia. Methods:
After ethical permission and informed consent, a prospective double blind randomized study was conducted at tertiary care hospital, from June
2022 to January 2024 in ASA Grade I or II patients aged 18 and older undergoing lumbar spine surgery under general anaesthesia. Eighty patients
were randomly assigned, 40 in each group, to receive either bupivacaine (0.25%) or ropivacaine (0.2%) via epidural infusion with fentanyl. The
patients were evaluated for VAS score, motor blockade at pre decided time points (0, 8, 16, 24, 36, 48 hours) and time taken to perform specific
manoeuvres. Both the groups were comparable with respect to demographic data and ASA grading. The vi Results: sual analog scale (VAS) scores
were comparable at rest and during coughing between the bupivacaine and ropivacaine groups at 0, 8, and 36 hours, but ropivacaine provided
significantly better pain relief at 16 and 24 hours. The VAS scores at mobilization showed no significant differences between Bupivacaine and
Ropivacaine at 0, 8 hours. However, Ropivacaine showed better pain relief at 16, 24, 36 and 48hours. The motor block assessment showed no
significant differences between Bupivacaine and Ropivacaine at 0, 8, 24 and 36 hours. However, at 16 hours with Ropivacaine showed less motor
blockade. Ropivacaine was associated with better functional outcomes in terms of maneuvers like turning, standing in front of the bed, walking,
and using the toilet, compared to Bupivacaine. Conclusion: For postoperative pain, ropivacaine was more effective than bupivacaine, providing
better VAS scores, less motor blockade, and earlier mobility
GASTROENTERITIS INDUCED POLYCYTHEMIAAND AKI : A CASE REPORT
Authors: Gupta Yatin
Published: February 2025

Summary: A30 year old male patient presented with complaints of 18-20 episodes of loose watery stools and 10-12 episodes of vomiting for the
last one day .He was admitted with the diagnosis of Acute Gastroenteritis with Severe Dehydration with Metabolic Acidosis . On examination he
was found to have features of severe dehydration and on investigation he was found to have Polycythemia and AKI as well. His hemoglobin level
was as high as 21.0 gm/dl which is very rare. On rehydration and other treatment all the three ailments got cured and the polycythemia which he had
was Relative Polcythemia and not primary polycythemia .
Utilization of local gum Arabic as an adhesive for the production of particle board from maize cobs and coconut shells
Authors: Ainerua E. O. , Jock A. A., , Bassey J. S.
Published: February 2025

The increase in the cost of building and furniture materials like particle board, ceiling and roofing sheets in Nigeria worsens by the day. The development of an alternative to curb this menace using agricultural waste such as maize cobs and coconut shells are required. In this study, maize cob, coconut shell and gum Arabic as adhesive were used in the development of particle board. The particle board was produced by mixing maize cob and coconut shell in different proportion. The physical and mechanical properties of the particle board such as density, water absorption, impact strength. compressive and tensile tests were investigated. The density ranged from 518.6 -843.3 Kg/m3, water absorption was between 11.05 and 70.2% by varying time of immersion at 30min, 1hr and 2hr. The compressive strength, tensile strength and impact strength fell within the range of 15.9 - 20.15MPa, 18 - 62KPa and 175 - 274.06KJ/m2 respectively. The results showed that the maize cob, coconut shell and gum Arabic are good candidates for building and furniture applications.
Energy Theft and Fault Detection in Smart Energy Meter Using Fuzzy Logic
Authors: Amusan A. , Waleola O. , Hassan A.
Published: February 2025

Energy theft and fault is a significant global issue in the energy sector, which accounts for non-technical loss in power utilities. Specifically, in Nigerian context, energy theft arises from meter tampering to reduce energy consumption readings, unauthorized or illegal connections, and meter swapping. The nexus of Internet of Things and Fuzzy logic learning techniques applied in smart metering system could mitigate this endemic problem. While there are efforts in literature that address this problem. However, there is still need for an optimal and smart metering system with an increased intelligence and accuracy to address energy theft and fault detection problem in distribution network. Hence, this work presents a solution to energy theft and fault detection in the distribution network by designing a smart energy metering system that applies simple fuzzy logic rules to analyze data thereby detecting theft and fault in the system. The system compares the measurements from a pole-based smart meter and consumer unit meter for detection of fault and theft. The smart energy meter is designed with a microcontroller and uses Wi-Fi communication for data transmission from pole-based metering point and consumer unit metering point to the central server for analysis and processing. The result shows that Fuzzy logic is useful in solving energy theft and fault detection problems. The accuracy and precision are 95% and 95% respectively for theft detection as well as 91% and 95% for fault detection.
Demokratische Regierungssysteme
Authors: Ganghof Steffen
Published: February 2025

Demokratien unterscheiden sich grundlegend in ihren Regierungssystemen: Wie wird die Regierung ausgewählt und abberufen? Und in welchem Verhältnis steht sie zu Wählern, Parlament und Staatspräsident? Steffen Ganghof erläutert die Grundlagen demokratischer Regierungssysteme – auf dem neuesten Stand der Forschung und anhand von Beispielen aus aller Welt. In kurzen, übersichtlichen Kapiteln behandelt er sowohl Basiswissen als auch häufig vernachlässigte Themen wie die direkte Abwahl des Präsidenten durch die Bürger oder die Rolle zweiter Parlamentskammern. Studierende der Politik- und Sozialwissenschaften und interessierte Bürger erhalten so ein tieferes Verständnis der repräsentativen Demokratie, was nicht zuletzt die Widerstandsfähigkeit des politischen Systems gegen Autokratisierungstendenzen stärken soll.
Politische Theorie
Authors: Schwaabe Christian
Published: February 2025

Die Neuauflage bietet einen Überblick über die wichtigsten Ansätze des westlichen politischen Denkens von der Antike bis in die Gegenwart.
Behandelt werden Platon, Aristoteles, Cicero, Augustinus, Machiavelli, Hobbes, Locke, Rousseau, Kant, Marx, Weber, Habermas, Rawls und Rorty. Im letzten Kapitel werden postmoderne und poststrukturalistische Ansätze besprochen, die für die aktuellen Debatten des Faches von zentraler Bedeutung sind (neben Rorty u. a. Foucault, Derrida, Lyotard und Mouffe).
Controlling
Authors: Friedl Birgit
Published: February 2025

Das Controlling ist Dreh- und Angelpunkt differenzierter und dezentraler Planungen und Entscheidungen in Unternehmen. Birgit Friedl hat mit diesem Lehrwerk eine umfassende und verständliche Basis für eine gezielte Prüfungsvorbereitung geschaffen. Durch die Zweiteilung des Stoffes in Grundlagen einerseits und Aufgaben und Instrumente andererseits können sich Dozenten und Studierende gezielt mit den für sie relevanten Teilbereichen befassen.
Das Controlling ist ein noch junges Teilgebiet der Betriebswirtschaftslehre, das sich sehr rasch entwickelt. Ziel dieses Buches ist es nicht, einen Überblick über alle Entwicklungen zu geben. Es handelt sich vielmehr um eine Einführung, die sich an Studierende und alle Interessierten richtet, die sich beruflich mit Fragen des Controlling beschäftigen.
Differences in the Prevalence of Allergy and Asthma before During and after the COVID-19 Pandemic (Article Reviews)
Authors: Elbasha Dr. Amal Ashour , Elbasha Dr. Huda Ashour
Published: February 2025

The increasing prevalence of allergies and asthma has become a significant global socioeconomic burden. The COVID-19 pandemic has dramatically changed the health and lifestyles of children and adolescents, but its impact on allergies and asthma remains unclear due to limited studies. This article aims to explore the differences in the prevalence of allergies and asthma among children and adolescents before during and after the COVID-19 pandemic, using data from various regions. COVID-19 increases the risk of new-onset asthma, and vaccination may reduce this risk by preventing COVID-19, particularly in older individuals. Further research is needed to explain these finding. Data were core databases and supplemented by browsing health information journals and citation searching. Asthma It is the most common chronic respiratory disorder in children, is a heterogeneous disease characterized by chronic airway inflammation and hyperresponsiveness that causing repeated cough, wheezing, chest tightness and shortness of breath, with prevalence approximately 14% of children worldwide, a prevalence much higher than that among adults (7.7%) [1] The purpose of this study is to investigate the incidence of asthma in children before and after the COVID-19 pandemic and explore potential contributing factors. Asthma diagnosis rates, demographic factors, and environmental exposures were compared. The study included Children and adolescents Adolencents with a documented diagnosis of asthma (ICD-10 code J45) were included. Exclusion criteria included pre-existing chronic respiratory conditions other than asthma.
mpact of Nutritional Status and WBC Count on Outcomes in Childhood Acute Lymphoblastic Leukemia Therapy
Authors: Khan Dr. Tasnuva , zaman Dr. Md. Ashaduz , Saief Dr. Mirza Md , Mark Dr. Sayeef Hossain Khan , Khan Dr. Rasif Hossain , Chowdhury Dr. Mubina Nuzhat , Khan Dr. Salwa , Khan Dr. Safinaz
Published: February 2025

Background: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy worldwide. Prognostic factors, including nutritional status and white blood cell (WBC) count at diagnosis influence treatment outcomes. Malnutrition weakens immune function, leading to infections and treatment delays, whereas hyperleukocytosis is associated with a poor prognosis. Understanding these factors is important for optimizing treatment strategies. This study aimed to evaluate the impact of nutritional status and white blood cell (WBC) count on treatment outcomes in childhood ALL. Methods: This cross-sectional study was conducted at the Department of Pediatric Hematology and Oncology, Bangabandhu Sheikh Mujib Medical University (BSMMU) from January to June 2013. Fifty children aged 1–15 years with newly diagnosed ALL, who received induction therapy, were included. Nutritional status was assessed using body mass index (BMI) (≥5 years) and weight-for-height (<5 years). WBC count was categorized as <50,000/mm³ and >50,000/mm³. Data were analyzed using SPSS, with statistical significance set at P <0.05. Results: Among the 50 patients, 62% were aged ≥5 years and 56% were male. Malnutrition was observed in 40% of the patients, and 66% had hyperleukocytosis (>50,000/mm³). Mortality was 100% among patients with WBC count >50,000/mm³. Malnourished children have prolonged neutropenia and higher infection rates with 10% mortality. Hyperleukocytosis was significantly associated with treatment failure and mortality (p<0.05). Conclusion: Nutritional status and WBC count were critical predictors of ALL treatment outcomes. Early nutritional interventions and risk-adapted treatment strategies can improve patient survival. A multidisciplinary approach is essential to improve patient outcomes.
A Comparative Study to Assess Illness Perception, Quality of Life and Self Care among Men and Women with Diabetes Mellitus Visiting for Follow Up in a Selected Hospital at Bagalkot, City
Authors: Bhagyalaxmi Ms. , .J Ms. Ancy P , Savitri Ms. , Santosh Mr. , Sowmya Ms. , Deepa Ms. , Basavaraj Mr. , Patil Dr. Ninganagouda G , Natekar Dr. Deelip S.
Published: February 2025

Background of the study: The prevalence of diabetes mellitus (DM) has been increasing all over the world in past 30 years, and particularly higher prevalence is seen in the Indian Subcontinent. India is a country with second highest number of people with type 2 DM. Apart from regular medications, there are other beneficial activities that can help in improvement of quality-of-life among patients with diabetes and can lead to better prevention and control of imminent complications such as diabetes. Aim: To find the comparison on illness perception, quality of life and self care among men and women with diabetes mellitus Patients. Materials and methods: Total 200 samples were selected by purposive sampling technique. 88 women and 112 men were selected. The standardized tools were used to assess the quality of life, self care and illness perception level. The data was collected for a period of 8 weeks in a selected hospital OPD. Unpaired t test and chi square test was used to compare the variables and find the association respectively. Graphs and tables were used to describe the data collected by the samples. Results: The study results reveal that majority Male (71.59%) of the DM patients were in the group of low experimental threat, Female (32.14%) of the DM patients were in the group of high. Male (29.54%) of the DM patients were in the group of high, Female (27.67%) of the DM patients were in the group of low experimental threat. Male (29.54%) and Female (18.75%) of the DM patients were in the group of moderate. Regarding quality of life shows that majority Male (73.32%) and Female (64.77%) of the DM patients were in the group of good category. Male (21.42%) and Female (28.40%) of the DM patients were in the group of vary good category. Male (6.25%) and Female (6.81%) of the DM patients were in the group of moderate. In regards of self care it shows that the majority Male (65.17%) and Female (55.68%) of the DM patients were in the group of good category. ...
The Influence of Artificial Intelligence and Electronic Word of Mouth (eWOM) on Consumer Purchasing Decisions
Authors: Saleh Farrel Alfarabi
Published: February 2025

This study aims to analyze the effect of using artificial intelligence (AI) algorithms and electronic word of mouth (eWOM) on consumer purchasing decisions on the TikTok social media platform, with a focus on fashion products in the Greater Jakarta area. This study focuses on Generation Z and Millennials as the research population. This study used a quantitative approach with a survey involving 358 active respondents who met the criteria. The research model examines the relationship of variables such as Purchase Duration, Product Recommendation, Social Media Dependency, and Consideration Set, as well as the impact of eWOM on purchasing decisions. The results showed that Product Recommendation and Social Media Dependency have a significant influence on Consideration Set, which in turn influences consumer purchasing decisions. On the other hand, Purchase Duration does not have a significant influence on Consideration Set in the context of fashion purchases through TikTok. In addition, perceived eWOM was found to play an important role as an external factor that directly influences purchasing decisions. These findings provide insights for fashion industry players and digital platforms to optimize AI and eWOM-based marketing strategies, to increase consumer engagement and drive purchase decisions in the social media era.
The Moderation Effect of Boycott Counternarrative on the Effect of Animosity on Purchase Amount
Authors: Isjwardhani Fawzia Rahmah Gieza
Published: February 2025

This study aims to empirically test the boycott counternarrative and how it affects the McDonald's boycott case that occurred in Indonesia, especially in Jakarta, Bogor, Depok, Tangerang, and Bekasi. The boycott campaign occurred as a result of the war between Israel and Palestine and is related to America which has diplomatic relations with Israel as the country of origin of McDonald's. This study refers to the theory of planned behavior and analyzes how it is applied in the context of a boycott. This study was conducted on McDonald's consumers spread across Jabodetabek and exposed to information related to the counter-boycott narrative targeted at McDonald's. The study was conducted on 377 respondents and the data obtained will be processed using structured equation modeling. This study is expected to provide an overview of whether the boycott counternarrative has succeeded in weakening the effect of animosity over McDonald's which provides support for the Israeli army on the purchase amount of respondents at McDonald's. Specifically, there have been no studies that empirically study the boycott counternarrative either in the context of McDonald's or in other contexts. The results of data processing using the PLS-SEM method show that boycott counternarrative has an effect on purchase amount by moderating the indirect relationship between animosity and purchase amount. This condition is in accordance with the research hypothesis which states that boycott counternarrative causes an increase in purchase amount from the moderation effect on the interaction of the boycott attitude variable with boycott intention. The moderating effect of boycott counternarrative on the indirect relationship between the animosity variable and purchase amount provides novelty for research that develops the theory of planned behavior.
The Effect of Green Marketing on Green Purchase Intention of The Body Shop Products Moderated by Environmental Attitude and Environmental Knowledge
Authors: Fadhilah Choirunnisa
Published: February 2025

In response to the growing demand for sustainable practices, green marketing has emerged as a pivotal approach for companies to engage environmentally aware consumers. This study investigates the impact of green marketing—measured through green product, green price, green promotion, and green place—on green purchase intention, with environmental attitude and environmental knowledge as moderating variables. Focusing on The Body Shop’s personal care products, the research examines Generation Z and Millennial consumers in the Jabodetabek area, Indonesia, who are aware of the brand but have not yet made a purchase. Using an online survey, data were collected from 274 respondents and analysed through Partial Least Squares Structural Equation Modelling (PLS-SEM). The results reveal that green promotion and green place significantly enhance green purchase intention, while green product and green price do not. Moreover, environmental attitude strengthens the relationship between green product and green purchase intention, while environmental knowledge positively moderates the influence of green price and green promotion on green purchase intention. These findings highlight the importance of prioritizing promotional efforts and distribution strategies in green marketing while addressing gaps in environmental knowledge to maximize consumer engagement. The insights provide valuable guidance for businesses in designing effective green marketing strategies tailored to the Indonesian market, contributing to broader sustainability goals.
The Effect of Vertical Mergers and Acquisitions (M&A) on the Value of Global Energy Sector Companies
Authors: Rusyda Rania , Prijadi Ruslan
Published: February 2025

This study aims to analyze the impact of vertical mergers and acquisitions (M&A) on firm value in the global energy sector, distinguishing vertical integration into upstream, downstream, and other categories. The background of this research is that, in the energy sector, most companies tend to acquire target firms operating in the same sector. This study adopts a quantitative approach by collecting data from Refinitiv and S&P Capital. The data consists of energy companies engaged in M&A activities during the 2014-2018 period and evaluates their impact on firm value over five years following the transactions. A total of 443 deals were analyzed using the Difference-in-Differences (DID) method. The results indicate that upstream and other vertical integrations have a significant positive impact on firm value, while downstream vertical integration shows a significant negative impact on firm value.
The Role of Influencer Marketing and Online Customer Review on Brand Attitude in Increasing Brand Loyalty, Brand Awareness, and Purchase Intention in Fashion Brands in Indonesia
Authors: Anugrah Siska
Published: February 2025

This study aims to analyze the influence of influencer marketing on consumer attitudes (brand attitude), brand loyalty, brand awareness, and electronic Word of Mouth (eWOM) in driving purchase intentions in Indonesia’s fashion industry. Using a quantitative approach, data were collected from 300 respondents via online surveys and analyzed through Structural Equation Modeling (SEM). The findings reveal that influencer credibility, attractiveness, involvement, and influencer-brand congruence do not significantly affect brand attitude. However, online reviews and brand-consumer congruence enhance loyalty, brand awareness, and purchase intention. This study offers insights for fashion marketers in selecting suitable influencers and managing customer reviews effectively.
Perbandingan Keakuratan CT Angiography dan MRI dalam Diagnosa Penyakit Arteri Koroner: Tinjauan Literatur Sistematis
Authors: Nurifin Stevany
Published: February 2025

Penyakit arteri koroner (PAC) merupakan penyebab utama morbiditas dan mortalitas global akibat penyempitan atau penyumbatan arteri koroner oleh plak aterosklerotik, yang dapat menyebabkan iskemia miokard, angina pektoris, infark miokard, gagal jantung, hingga kematian mendadak. Diagnosis yang akurat sangat penting untuk memastikan intervensi medis yang tepat waktu. Penelitian ini bertujuan untuk membandingkan efektivitas computed tomography angiography (CTA) dan magnetic resonance imaging (MRI) dalam mendeteksi PAC. Metode yang digunakan adalah tinjauan literatur sistematis terhadap 50 studi relevan yang membahas keakuratan kedua modalitas pencitraan ini. Hasil penelitian menunjukkan bahwa CTA memiliki sensitivitas dan spesifisitas rata-rata masing-masing 95% dan 97%, sementara MRI memiliki sensitivitas 89% dan spesifisitas 94%. CTA unggul dalam resolusi spasial tinggi untuk visualisasi anatomi arteri koroner, meskipun memiliki keterbatasan berupa paparan radiasi ionisasi dan risiko reaksi alergi terhadap media kontras. Sebaliknya, MRI lebih aman karena tidak menggunakan radiasi dan dapat mengevaluasi fungsi jantung, perfusi miokard, serta viabilitas jaringan, sehingga cocok untuk pasien dengan risiko tinggi atau kebutuhan pemeriksaan berulang. Hasil penelitian ini menunjukkan bahwa kombinasi CTA dan MRI melalui pendekatan hybrid imaging dapat meningkatkan akurasi diagnostik secara komprehensif. Oleh karena itu, pemilihan modalitas pencitraan harus mempertimbangkan kondisi klinis pasien dan tujuan pemeriksaan untuk meningkatkan kualitas diagnosis PAC serta efektivitas pengelolaan penyakit ini.
Manajemen Isu Pemerintah Daerah Istimewa Yogyakarta Terkait Polemik Sampah di Daerah Istimewa Yogyakarta
Authors: Hendrian Gugus , Deslia Iva Fikrani
Published: February 2025

Permasalahan pengelolaan sampah di Daerah Istimewa Yogyakarta (DIY) telah menjadi perhatian serius, terutama dengan ditutupnya Tempat Pembuangan Akhir (TPA) Piyungan pada tahun 2023 akibat kapasitas yang berlebihan. Penelitian ini bertujuan untuk menganalisis strategi manajemen isu yang diterapkan oleh pemerintah daerah dalam menangani krisis sampah. Sebagai provinsi dengan tingkat kunjungan wisata yang tinggi, DIY menghadapi tantangan besar dalam menjaga keberlanjutan lingkungan di tengah pertumbuhan penduduk yang cepat, infrastruktur pengelolaan sampah yang terbatas, dan rendahnya kesadaran masyarakat. Dengan pendekatan kualitatif, penelitian ini mengeksplorasi upaya hubungan masyarakat pemerintah dalam menyampaikan informasi, mendidik masyarakat, dan melibatkan pemangku kepentingan dalam solusi pengelolaan sampah. Penelitian ini juga menyoroti dimensi teknis, sosial, ekonomi, dan politik dari pengelolaan sampah, dengan menekankan pentingnya strategi holistik yang melibatkan pemerintah, LSM, sektor swasta, dan masyarakat. Temuan penelitian menunjukkan bahwa meskipun telah dilakukan berbagai kampanye kesadaran dan regulasi, upaya tersebut sering kali gagal menghasilkan perubahan perilaku yang nyata atau menyediakan solusi yang berkelanjutan. Penelitian ini menyimpulkan bahwa manajemen isu yang efektif memerlukan pendekatan terintegrasi yang menyelaraskan proses pengelolaan sampah dari hulu ke hilir, meningkatkan partisipasi masyarakat, dan memperkuat kolaborasi antar pemangku kepentingan. Langkah-langkah ini sangat penting untuk memulihkan citra Yogyakarta sebagai destinasi yang bersih dan berkelanjutan bagi penduduk dan wisatawan.
Estimulação Cerebral Profunda no Tratamento da Doença de Alzheimer, Parkinson e Outras Demências
Authors: Barbosa Guerra Rodrigo , Moreira Sathler Maria Vitória , Caroline Lopes Pinho Jéssica , Daniel Fernandes Almeida Gianluca , Aryel Rodrigues de Almeida Lima Fernanda , Bruno Oliveira Diniz Emerson , Araujo Pereira Itan , Ferreira Tomé Ribeiro Tatyane , Francisco Honorato da Nóbrega5 João , Do Rosário Costa Igor , Luiz Teixeira do Vale André , Caldeira de Faria Santiago Marianne , Almeida Silva Rocha Lucas , Gonçalo Pereira de Moura Henrique
Published: February 2025

A DBS tem evoluído de uma abordagem para transtornos do movimento, como Parkinson, para uma potencial terapia para doenças neurodegenerativas, incluindo Alzheimer. Avanços tecnológicos, como eletrodos direcionais e algoritmos de estimulação, melhoraram a precisão e reduziram efeitos adversos. Revisões sistemáticas e ensaios clínicos indicam que a DBS pode modular circuitos cerebrais envolvidos na cognição e memória, mas a falta de padronização nos parâmetros de estimulação limita sua aplicabilidade. Enquanto estudos sugerem benefícios na estabilização da função cognitiva, desafios éticos e de segurança, como vulnerabilidades digitais, ainda precisam ser abordados. A pesquisa contínua é essencial para estabelecer a DBS como um tratamento eficaz e seguro para demências.
Avanços e Desafios na Cirurgia de Emergência: Abordagens Contemporâneas no Manejo de Traumas Abdominais
Authors: Francisco Adriano Pereira Filho  , Daniel Araújo Pinheiro  , Daniel Gonçalves Menegazzo  , Diandra Santos de Souza  , Diana Tais dos Santos Maia  , Luciane Gil Varaschini  , Larissa de Souza Pedreira  , Milena Lima dos Santos  , Raquel Pires Bispo Andrade  , Salete Guterres  , Sthefanny Lorrany Veloso Borges  , Victor Monteiro de Campos Raya
Published: February 2025

A cirurgia de emergência, particularmente no manejo de traumas abdominais, é um dos campos mais desafiadores da medicina, devido à necessidade de um diagnóstico rápido e de decisões cirúrgicas precisas. Nas últimas décadas, houve avanços significativos em diversas áreas, como nas técnicas cirúrgicas, com destaque para a laparoscopia, e nas tecnologias de diagnóstico, como a tomografia computadorizada (TC), que têm melhorado a precisão na identificação de lesões abdominais. O trauma abdominal, causado por acidentes automobilísticos, quedas ou violência, continua a ser uma das principais causas de morbidade e mortalidade, exigindo uma abordagem rápida e eficiente. Embora as técnicas minimamente invasivas ofereçam benefícios, como menor tempo de recuperação e menos complicações, a aplicação dessas abordagens ainda enfrenta desafios, como a falta de infraestrutura e treinamento adequado em algumas regiões. Além disso, o tratamento pós-operatório, com controle da dor e prevenção de infecções, permanece um desafio constante. A evolução de novas tecnologias, como a inteligência artificial e a cirurgia robótica, promete melhorar ainda mais os resultados e a precisão no manejo de traumas abdominais, mas o acesso a esses avanços ainda é desigual. O tratamento de traumas abdominais não complicados com abordagens conservadoras tem se mostrado eficaz em muitos casos, minimizando a necessidade de intervenções cirúrgicas. A medicina personalizada, com o uso de biomarcadores e dados genéticos, está começando a ser explorada como uma ferramenta para otimizar os tratamentos e melhorar os resultados dos pacientes.
Principais tipos de arritmias cardíacas e seus manejos mais comuns
Authors: Castro Lisboa Thássia Mirelly Xavier de , Vitória Queiroz Lima Camilly , Eduarda Gomes Miguel Maria , De Oliveira Dias Thalisson , José Martins Fernando , Coelho de Medeiros Rodrigo Marinho , Magalhães Teixeira Maria Alice Oliveira , Parente Santos Gebes Vanderlei , Strassacapa Chociai Camila , Rosa Passaglia Lucia , Lima Bruno Guilherme Da Silva
Published: February 2025

O presente estudo trata-se de uma revisão narrativa de caráter crítico e analítico, na  pesquisa  sobre os principais  conceitos  no que tange as arritmias cardíacas e seu manejo comum. Foi  realizada  uma  revisão  de  artigos  nas  bases  de  dados   Scientific  Electronic  Library  Online (SciELO) e PubMed, com os seguintes Descritores em Ciências  da  Saúde  (DeCS): Arritmias; Cardiologia; Emergência. Selecionando artigos entre os períodos de 2000 a 2025, nos idiomas Inglês,  Português e Espanhol para ampliar o nível de relevância e a qualidade da revisão, além do embasamento técnico-científico advindo de obras literárias conceituadas pela história. A avaliação das arritmias cardíacas tem como objetivo identificar o local do distúrbio de condução, os ritmos atriais e ventriculares presentes, bem como a interação entre os impulsos atriais e ventriculares. O uso de derivações padrão de ECG é fundamental para a análise detalhada do ritmo cardíaco, sendo as derivações II e V1 as mais indicadas, pois oferecem as amplitudes máximas das ondas P e QRS, facilitando a avaliação da relação entre os impulsos supraventriculares e ventriculares.A avaliação e o manejo das arritmias cardíacas são fundamentais para o diagnóstico e tratamento adequado das condições que afetam o ritmo cardíaco. A utilização de derivadas padrão de ECG, como II e V1, permite uma análise detalhada do distúrbio de condução e facilita a identificação de alterações isquêmicas e rítmicas. A classificação das arritmias, considerando sua origem, frequência e condução do impulso, é essencial para a definição de estratégias terapêuticas eficazes, visando corrigir as causas precipitantes, restaurar o ritmo sinusal e prevenir recaídas.
Tomographic aspects of common variable immunodeficiency suggestive of lymphocytic granulomatous interstitial lung disease: a systematic review
Authors: Sousa Lucas Costa Amaral de , Amorim Caroline Alencar , Hunt Shannon de Oliveira , Santana Juliana Silva de , Marques Danilo de Santana , Motta Daniela de Lucena
Published: February 2025

Objective: Common variable immunodeficiency (CVID) is a primary antibody deficiency characterised by hypogammaglobulinemia, leading to the occurrence of infections and at times, the development of diffuse lesions with granulomatous characteristics and lymphoproliferative histopathological patterns. Granulomatous lymphocytic interstitial lung disease (GLILD) is a rare form of interstitial lung disease where imaging exams play a crucial role, therefore this article aims to assess the prevalence of tomographic findings and evaluate whether bronchiolitis and ground glass opacity are suggestive findings for the diagnosis of GLILD in patients with CVID without a previous GLILD diagnosis. Method: a systematic review using the prisma methodology was conducted with five descriptors across four databases, covering publications from 2012 to 2022 in the portuguese, english, and spanish languages. Results: out of 234 initial results, 26 articles were included, representing a total of 775 analysed CVID patients. Various radiographic abnormalities were identified, with notable findings including bronchiectasis, pneumonia, atelectasis, among others. Conclusion: the results indicate that it is not possible to establish a pattern of tomographic findings, demonstrating the heterogeneity in the presentation of glild.
A PERCEPÇÃO DOS PAIS QUANTO AO MANEJO E AVALIAÇÃO DA DOR AGUDA NÃO CIRÚRGICA PEDIÁTRICA NAS INSTALAÇÕES DE SAÚDE
Authors: HAIDA AMANDA MARIKO , Manchini Maria Fernanda , Campiolo Edmara Laura , Guimarães Cássia Regina Nogueira
Published: February 2025

Objetivo: Realizar uma revisão sistemática qualitativa com metassíntese sobre o manejo e a avaliação da dor aguda não cirúrgica em crianças, segundo a percepção de seus acompanhantes.
Introdução: A dor aguda pediátrica é prevalente, mas frequentemente negligenciada. Compreender a percepção dos cuidadores sobre seu tratamento e avaliação, fora do contexto pós-operatório, é essencial. Diante da ausência de uma síntese sobre o tema, esta revisão foi desenvolvida.
Critérios de inclusão: Estudos com responsáveis por crianças de 28 dias a 12 anos que buscaram atendimento para dor aguda (≤3 meses) não cirúrgica, decorrente de lesão ou condição médica. Foram incluídos artigos que investigaram a percepção dos cuidadores sobre o manejo da dor por profissionais da saúde, com acesso gratuito e abordagem qualitativa (fenomenologia, teoria fundamentada, etnografia, pesquisa-ação e pesquisa feminista).
Métodos: A busca foi realizada em PubMed, Scielo e Scopus (março/2024), incluindo estudos em inglês ou português, publicados entre 2010 e 2024, com os termos selecionados no título e/ou resumo. Os títulos e resumos foram triados conforme os objetivos da revisão, e os estudos relevantes foram analisados integralmente. A qualidade metodológica e os dados extraídos (metodologia, população, intervenção, resultados) foram avaliados por instrumentos padronizados. Os achados foram organizados em categorias e sintetizados.
Resultados: Três estudos foram incluídos, gerando duas metassínteses a partir de cinco categorias e 37 achados: i) acompanhantes sentiram que suas experiências e o contexto familiar/cultural não foram considerados adequadamente; ii) os pais avaliaram o desempenho da equipe na avaliação da dor como deficiente.
Conclusão: Cuidadores desejam uma abordagem mais proativa, inclusiva e colaborativa dos profissionais da saúde. A parceria entre profissionais, crianças e acompanhantes poderia
Pertenencia a grupos coercitivos como adicción social /
Authors: Mora Galán Manuel
Published: February 2025

El presente trabajo aborda la problemática de la adicción social como una forma de
dependencia emocional y psicológica en el contexto de las organizaciones coercitivas,
colectivos que utilizan técnicas de manipulación psicológica para controlar a sus
adeptos. El objetivo principal ha sido explorar cómo se manifiesta esta adicción en
dichos grupos, analizando sus dinámicas, consecuencias e implicaciones, y mostrando
las características psicológicas y sociales de la adicción social desde las técnicas
coercitivas utilizadas por estas organizaciones.