bluuebunny/crossref_metadata_2025 huggingface dataset:
Different Fgfs have distinct roles in regulating neurogenesis after spinal cord injury in zebrafish
Authors: Goldshmit Yona , Tang Jean Kitty K. Y. , Siegel Ashley L. , Nguyen Phong D. , Kaslin Jan , Currie Peter D. , Jusuf Patricia R.
Published: November 2018

Background

Despite conserved developmental processes and organization of the vertebrate central nervous system, only some vertebrates including zebrafish can efficiently regenerate neural damage including after spinal cord injury. The mammalian spinal cord shows very limited regeneration and neurogenesis, resulting in permanent life-long functional impairment. Therefore, there is an urgent need to identify the cellular and molecular mechanisms that can drive efficient vertebrate neurogenesis following injury. A key pathway implicated in zebrafish neurogenesis is fibroblast growth factor signaling.

Methods

In the present study we investigated the roles of distinct fibroblast growth factor members and their receptors in facilitating different aspects of neural development and regeneration at different timepoints following spinal cord injury. After spinal cord injury in adults and during larval development, loss and/or gain of Fgf signaling was combined with immunohistochemistry, in situ hybridization and transgenes marking motor neuron populations in in vivo zebrafish and in vitro mammalian PC12 cell culture models.

Results

Fgf3 drives neurogenesis of Islet1 expressing motor neuron subtypes and mediate axonogenesis in cMet expressing motor neuron subtypes. We also demonstrate that the role of Fgf members are not necessarily simple recapitulating development. During development Fgf2, Fgf3 and Fgf8 mediate neurogenesis of Islet1 expressing neurons and neuronal sprouting of both, Islet1 and cMet expressing motor neurons. Strikingly in mammalian PC12 cells, all three Fgfs increased cell proliferation, however, only Fgf2 and to some extent Fgf8, but not Fgf3 facilitated neurite outgrowth.

Conclusions

This study demonstrates differential Fgf member roles during neural development and adult regeneration, including in driving neural proliferation and neurite outgrowth of distinct spinal cord neuron populations, suggesting that factors including Fgf type, age of the organism, timing of expression, requirements for different neuronal populations could be tailored to best drive all of the required regenerative processes.
Systematic Review of the Efficacy and Safety of Gabapentin and Pregabalin for Pain in Children and Adolescents
Authors: Egunsola Oluwaseun , Wylie Claire E. , Chitty Kate M. , Buckley Nicholas A.
Published: November 2018

The barriers to opioid use in some countries necessitate the need to identify suitable alternatives or adjuncts for pain relief. The gabapentinoids (gabapentin and pregabalin) are approved for the management of persistent pain in adults, but not in children. Searches were conducted in Embase, Medline, Scopus, and Web of Science up until November 2017, for randomized controlled trials that investigated the analgesic effects of gabapentin or pregabalin in children and adolescents <18 years of age. A total of 7 publications were identified, 5 regarding gabapentin as prophylactic postsurgical pain relief for either adenotonsillectomy (n = 3) or scoliosis surgery (n = 2), and 1 for gabapentin treatment of chronic regional pain syndrome/neuropathic pain. One study investigated the efficacy of pregabalin as a treatment for fibromyalgia. Based on the studies’ primary outcomes alone, neither of the chronic pain studies involving gabapentin and pregabalin showed significant efficacy compared with amitriptyline or placebo, respectively. Two of the prophylactic gabapentin studies for adenotonsillectomy and idiopathic scoliosis surgery reported significantly fewer children requiring analgesia and lower opioid requirement, respectively, compared with placebo. Two of the identified clinical trials (conducted by the same first author) on the efficacy of gabapentin for prophylactic postadenotonsillectomy pain relief were omitted from narrative synthesis due to clear evidence of fabricated data. Overall, this review identified a paucity of evidence for the analgesic effect and safety of gabapentinoids in children. We also suggest audit of any current evidence-based practice and clinical guidelines that have cited the research studies with fabricated data.
Effectiveness of implementation of “mental health nursing students’ clinical competency model” on academic performance of nursing students
Authors: Atashzadeh-Shoorideh Foroozan , Mohtashami Jamileh , Pishgooie Seyed Amir Hosein , Jamshidi Tayebeh , Sedghi Sara
Published: November 2018

Background: Clinical nursing competence in mental health is one of the most important topics in theoretical and practical nursing training with many factors affecting it. The purpose of this study is to determine the impact of the implementation of the “mental health nursing students’ clinical competence model” on nursing students’ academic performance.

Methods: This study is a semi experimental following one group of student nurses. “mental health nursing students’ clinical competence model” for undergraduate nursing student’s education was applied. The study population included 50 nursing students, who were studying from fifth semester to seventh semester and selected through census sampling. During the seventh semester after the completion of theoretical and practical courses in mental health nursing, re-evaluation was conducted and the scores before and after the implementation of the clinical competence model were compared.

Results: Rate of clinical competency before the intervention, was estimated at the level of non-mastered; and after intervention was at the level of mastered, demonstrating a significant difference (p<0.001). Areas of clinical competency scores before and after the intervention were compared which showed significant difference in all the areas except the mental competency areas (p<0.05).

Conclusions: The implementation of the “mental health nursing students’ clinical competence model” and appropriate planning for achievement of mental health nursing specialized competency can ensure the achievement of clinical competency by nursing students.
ПСИХОЛОГИЧЕСКИЕ ОСОБЕННОСТИ ФУТБОЛЬНЫХ БОЛЕЛЬЩИКОВ: ФАНАТЫ И ХУЛИГАНЫ
Authors: Molchanova Elena Vladimirovna
Published: November 2018

Цель. В статье представлено теоретическое и экспериментальное исследование психологических особенностей представителей околофутбольной субкультуры – «фанатов» и «хулиганов». Целью экспериментального исследования стало выявление особенностей социальной фрустрированности, агрессивности и акцентуаций характера футбольных болельщиков.Метод или методология проведения работы. Библиографический метод; психодиагностический метод: анкетирование, методика «Уровень социальной фрустрированности» Л.И. Вассермана; опросник агрессивности А. Басса – А. Дарки; методика определения акцентуаций характера Г. Шмишека; математико-статистической метод обработки данных.Результаты работы. Футбольные болельщики в целом имеют низкую социальную фрустрированность, при этом если для «фанатов» областями негативных эмоций являются материальное положение и проведение отпуска, то для «хулиганов» – это современная обстановка в обществе и государстве и сфера медицинского обслуживания. Средние значения агрессивности и враждебности респондентов имеют повышенные показатели. Обнаружены статистически значимые различия в подгруппах «хулиганов» и «фанатов» по показателям негативизма, вербальной и физической агрессии. Стоит отметить, что футбольные болельщики не имеют ярко выраженных акцентуаций характера, а наиболее выраженными типами акцентуаций характера у обеих подгрупп являются гипертимный, застревающий и демонстративный.Область применения результатов. Полученные результаты дополняют немногочисленные работы по теме футбольной субкультуры и позволяют оптимизировать организацию массовых футбольных мероприятий, более эффективно решать возникающие конфликтные ситуации.Выводы. Представители околофутбольной среды, относящие себя к «фанатам» и «хулиганам», имеют психологические особенности и могут рассматриваться по уровню агрессивности как разные группы.
ОБРАЗ СОЦИАЛЬНО-ПСИХОЛОГИЧЕСКОГО ПРОСТРАНСТВА ГОРОДА в представлении МОЛОДЕЖИ С РАЗНЫМИ МИГРАЦИОННЫМИ НАМЕРЕНИЯМИ (НА ПРИМЕРЕ ГОРОДА КОМСОМОЛЬСКА-НА-АМУРЕ)
Authors: Bakina Anna Vladimirovna , Orlova Olga Aleksandrovna , Yaremtchuk Svetlana Vladimirovna
Published: November 2018

Тема, цель работы. Основной темой нашего исследования выступали особенности эмоционального отношения к людям, объектам и явлениям социально-психологического пространства города г. Комсомольска-на-Амуре у молодежи с разными миграционными намерениями.Метод и методологию проведения работы. В исследовании приняли участие 130 жителей города в возрасте 16–25 лет, разделенные на три группы: не собирающиеся менять место жительства, намеренные уехать из города при первой возможности и допускающие возможность переезда при определенных условиях. Для оценки эмоционального отношения к различным объектам социально-психологического пространства и изучения его структуры респондентам был предложен проективный модифицированный психогеометрический тест С. Деллингер. Исследование выстроено по типу репертуарной решетки, объектами оценки для респондентов выступали различные структурные компоненты социально-психологического пространства: коммуникативная сфера, возможности профессиональной и личностной самореализации, временные перспективы и территориальная идентичность испытуемых.Результаты и выводы. Анализ результатов показал, что молодежь с выраженными миграционными намерениями более негативно относится к Дальневосточному региону, его населению и своей настоящей жизни. Данная группа молодежи пространство города рассматривает как неэффективное для самореализации и саморазвития в настоящем и будущем и не идентифицирует себя с территорией проживания. Молодежь, которая хочет остаться в городе, рассматривает его как эффективное пространство для самореализации и саморазвития, имеет сформированную территориальную идентичность, позитивно относится к своей настоящей жизни, месту проживания и населению города.Область применения результатов. Результаты исследования могут быть применены в сфере проектирования социальной инфраструктуры, планирования молодежной и миграционной политики при реализации «Стратегии социально-экономического развития муниципального образования городского округа «Город Комсомольск-на-Амуре» до 2032 года».
ПСИХОЛОГИЧЕСКИЕ УСЛОВИЯ СНИЖЕНИЯ МОТИВАЦИИ ПЕРСОНАЛА ПОД ВЛИЯНИЕМ ВНЕШНЕГО ВОЗДЕЙСТВИЯ
Authors: Borisova Irina Ivanovna
Published: November 2018

Цель исследования. Статья посвящена изучению внешних психологических условий, снижающих мотивацию работника к осуществлению профессиональной деятельности. Задачами исследования являются: изучение отрицательного влияния внешних факторов на трудовые мотивы и описание негативных психологических особенностей условий снижения эффективности мотивационных воздействий.Методология проведения работы. Произведен анализ литературы и использованы эмпирические методы в процессе исследования. Метод исследования – тестирование испытуемых. После проведения тестирования полученные результаты подверглись статистической обработке в программе R.Результаты. Выявлена корреляция между внешней мотивацией и психологическими факторами. Сделаны выводы о негативном воздействии внешних психологических факторов на снижение мотивации к осуществлению эффективной профессиональной деятельности.Определены психологические условия, снижающие мотивацию работника, и предложены рекомендации для руководителей компаний.Область применения результатов. Результаты могут быть использованы управленческим аппаратом компаний.
A Libras como Proposta Educacional no Ensino Bilingue para Alunos com Surdez no Município de Belém
Authors: Sousa Cydriane Cristina Araújo de , Sena Bethânia Alves , Marques Marilene Dos Santos
Published: November 2018

O presente trabalho constitui-se em um recorte de pesquisa bibliográfica mais ampla que objetivou analisar a sobre a temática da Língua Brasileira de Sinais (LIBRAS) como Proposta Educacional no Ensino Bilíngue para alunos com surdez no município de Belém. Dessa forma, o trabalho discute como está sendo atribuídas as práticas educativas. Nesse sentido, levantou-se o seguinte questionamento acerca de que propostas educativas estão sendo utilizadas para os alunos com surdez nas series iniciais, no que diz respeito à literatura pesquisada com conhecimentos de alguns estudiosos da área, entre eles: Ferreira (2006) Lacerda(2000) Skilar(1999) Sanches(1993). Assim, buscou-se pensar numa inclusão para todos, onde surdos e ouvintes possam e devam aprender juntos caracterizando, dessa forma, um movimento eficaz dentro da educação inclusiva.
Marketing digital e os digital influencers: Breves comentários acerca dessa ferramenta e de sua eficácia na divulgação de bens e serviços
Authors: Sant´Anna André Luis
Published: November 2018

Resumo: o marketing digital tem se apresentado como ótima ferramenta para transações no mercado econômico. Um dos motivos dessa importância está relacionado ao aumento significativos das plataformas de comunicação online, para mais de 20% em 2013, refletindo na desvalorização de revistas e jornais impressos. Nesse novo cenário, com redes sociais, as pessoas tendem a se agruparem em comunidades com interesses semelhantes. Um dos líderes de junção de pessoas em uma mesma comunidade, são os digital influencers (influenciadores digitais), que são verdadeiros formadores de opiniões e tem sido amplamente utilizados como forma de marketing digital. Este artigo discute, com base na literatura especializada, o marketing digital. conclui-se que é fundamental o investimento no marketing digital, para fins de acompanhamento e adequação à era digital, como oportunidade de promoção de marcas e produtos e, fortalecimento de relacionamento com os clientes através dos digital influencers.
O Comércio Eletrônico como Estratégia Competitiva para a Sustentabilidade Empresarial
Authors: Galvão Jonas Pereira , Lima Márcia Maria Leite
Published: November 2018

Esse artigo tem como objetivo geral identificar os principais fatores que influenciam os consumidores a optar pelo comércio eletrônico. Para o alcance do mesmo, foi realizada uma pesquisa de opinião pública. A pesquisa conta com uma abordagem quantitativa, descritiva e exploratória, com amostra não probabilística. A pesquisa foi realizada na cidade de Porteiras-CE. O instrumento de coleta de dados aconteceu por meio de um questionário contendo 11 (onze) perguntas, sendo 08 (oito) fechadas e 03 (três) abertas. Como resultados, foram identificados que os preços acessíveis e as promoções influenciam os consumidores a realizarem compras na internet. Percebeu-se também que os serviços prestados pelo comércio eletrônico deixam um pouco a desejar, por conta das informações sigilosas e dados pessoais que são inseridas pelos clientes na internet.
Estresse Ocupacional: Uma análise sobre causas, consequências e prevenções em uma clínica médica na cidade de Juazeiro do Norte-CE
Authors: Alves Ana Lecia Pereira , Lima Márcia Maria Leite
Published: November 2018

Uma boa saúde ocupacional é algo importante dentro de qualquer empresa, seja qual for o seu propósito, toda empresa deve conter profissionais qualificados para a fomentação das suas atividades organizacionais, onde estas por vez devem estar alinhadas a pessoas capacitadas que se preocupem com o bem-estar organizacional, quanto com a saúde ocupacional dos colaboradores. Esse estudo tem por objetivo geral, estudar quais os fatores influenciadores do estresse ocupacional em uma clínica médica na cidade de Juazeiro do Norte- CE. Seguido dos objetivos específicos que é analisar se a comunicação é um fator influenciador, verificar se a cultura organizacional favorece a desmotivação do indivíduo dentro da organização, identificar se a qualidade de vida dentro da organização é satisfatória e investigar os danos que o estresse ocupacional pode ocasionar a saúde do trabalhador dentro da organização.  Para obter os resultados foi realizada uma pesquisa pelos métodos mistos Quanti-qualitativo, descritiva. Através do processo metodológico foi possível identificar os resultados que não foram satisfatórios aos objetivos, pois na pesquisa obteve-se que os agentes estressores são devidamente encarados e controlados se tornando assim fatores de crescimento ao colaborador.
A Percepção dos Empresários Sobre a Consultoria em Gestão de Pessoas na Região do Cariri
Authors: De Carvalho Márcia Marta , Rodrigues Larissa Vasconcelos
Published: November 2018

Percebe-se que consultoria é uma área bastante desafiadora nas organizações, pois tem papel de analisar as organizações com em suas esferas positivas e negativas, buscando a otimização de resultados. Assim, o objetivo dessa pesquisa é analisar a opinião dos empresários da Região do Cariri sobre a consultoria em Gestão de Pessoas, tendo como tipo de pesquisa quanti-qualitativa, por meio de dados coletados através de um questionário aplicado a 101 empresários da Região do Cariri, buscando verificar a opinião dos mesmos sobre consultoria em Gestão de Pessoas. Ao longo da pesquisa, destacam-se alguns conceitos de gestão de pessoas e consultoria empresarial relacionada ao tema apresentado. A pesquisa busca despertar uma atenção a consultoria em gestão de pessoas, sendo importantes para empresas na Região do Cariri analisar este ramo em busca de aumentar resultados nas suas organizações
Triptofano no Sono: Uma Revisão Sistemática baseada no Método PRISMA
Authors: Lima Leonardo Da Silva , Silva Carla Pequeno da
Published: November 2018

O sono é um processo biológico que apresenta alternância com períodos de vigília, modulado por hormônios e funções neuronais, tais como mecanismos fisiológicos que modificam a temperatura corporal, produção de hormônios e função cardíaca. Anormalidades no sono podem acarretar em má qualidade de vida e a longo prazo em doenças metabólicas e cardiovasculares. Acredita-se que um aliado para o tratamento das desordens do sono seja o triptofano (TRP), que por sua vez, é um aminoácido precursor da melatonina e serotonina. O TRP e alguns dos seus produtos metabólicos, como serotonina e melatonina, participa da regulação do humor, do sono e dos ritmos circadianos e são usados para tratar insônia e apnéia do sono. O objetivo desta pesquisa foi  identificar a eficácia do uso do triptofano no sono através de uma revisão sistemática no modelo PRISMA. A revisão sistemática foi realizada a partir de três bases de dados (PubMed, Lilacs e Scielo). Foram encontrados 1.034 artigos, sendo 876 da PubMed,  157 da Lilacs e 1 da Scielo, após a aplicação dos critérios de elegibilidade foram incluídos 8 artigos na revisão. Os estudos mostraram efeitos positivos da suplementação do triptofano no sono, este aminoácido mostrou-se ser eficaz até mesmo no tratamento de distúrbios relacionados ao sono.
Prevalência dos Acidentes de Motocicleta Envolvendo os Adolescentes de Quixadá
Authors: Barros Francisco Hilângelo Vieira , Silva Leonardo Oliveira , Roseno Maria Alcione Silva Gomes , Olinda Antônia Gomes de , Souza Joaquina Batista Rodrigues de , Amaral João Joaquim Freitas do
Published: November 2018

O impacto na sociedade e na saúde provocado pelos acidentes de trânsito tem sido extremamente registrado. O objetivo deste estudo retrospectivo e transversal foi conhecer o perfil epidemiológico dos acidentes de motocicletas em adolescentes do município de Quixadá-Ceará. Prevaleceu o sexo masculino (92%), entre 14 a 17 anos (52%), no ensino médio (86%), solteiros (71%), com renda familiar entre uma a três salários mínimos (53%), utilizavam a motocicleta para trabalhar (61%) e predominando a profissão mototaxista (43%). Em relação à motocicleta, 27% eram habilitados, 2% referiram conhecer o Código de Trânsito Brasileiro, 13% faziam uso do capacete, 65% não praticam direção defensiva, 02% conhecem a lei 11.705, 03% participaram de programas educativos. O estudo identificou o perfil epidemiológico e os possíveis fatores determinantes dos acidentes envolvendo os adolescentes. Conclui-se que é necessária a intensificação de campanhas educativas sobre acidentes de motocicleta em adolescentes, principalmente nas escolas.
O Processo de Terceirização de Serviços no Consórcio Águas do Ceará da Cidade de Brejo Santo-CE
Authors: Alves Nauanna Sampaio , Costa Antonia Valdelucia
Published: November 2018

A terceirização é importante para as empresas uma vez que racionaliza recursos, redefine suas operações, reduz custos, além de flexibilizar e enxugar as estruturas organizacionais. Ela auxilia na reestruturação organizacional, pois promove a competividade, aumento da produtividade e a consolidação da identidade e comprometimento da empresa no mercado em que atua. O objetivo geral deste estudo foi o de conhecer os benefícios percebidos pela empresa Consórcio Águas do Ceará, localizada na cidade de Brejo Santo-CE, a partir da terceirização de serviços. Como objetivos específicos: compreender, a partir da historicidade e da conceituação de terceirização, a relevância desse processo para as empresas; evidenciar as vantagens e desvantagens da terceirização em prol da qualidade do modo de gestão atual; conceituar e destacar a quarteirização como uma ferramenta competitiva da terceirização. A fundamentação teórica abordou temas relevantes ao estudo a partir da sua historicidade e conceitos acerca da terceirização, vantagens e desvantagens deste modelo de gestão e a quarteirização como ferramenta competitiva da terceirização. Quanto à tipologia da pesquisa, adotou-se como método o estudo de caso, com base bibliográfica, de cunho descritivo exploratório, com abordagem qualitativa.
Controladoria: A relevância da tecnologia da informação na qualidade dos relatórios contábeis.
Authors: Lima Douglas Alexandre Sampaio de , Macedo Maria Erilúcia Cruz
Published: November 2018

O presente trabalho busca apresentar a contribuição da tecnologia da informação diante da qualidade dos relatórios contábeis, pois com o desenvolvimento e evolução da tecnologia a contabilidade necessita está atualizando-se diariamente para atender à necessidade dos gestores de modo a auxilia-los diante das tomadas de decisões para obter vantagens competitivas diante dos demais concorrentes, visto que os consumidores estão cada vez mais exigentes na escolha de propostas vantajosas em suas compras. Deste modo buscou-se desenvolver os conceitos de sistemas de informações e suas funções paralelo a evolução da contabilidade através de pesquisa bibliográfica, descritiva e qualitativa em obras já publicadas sobre o tema. Portanto a tecnologia da informação possibilita que os relatórios contábeis possuam informações detalhadas da situação real das organizações eficazes e eficientes na tomada de decisão interna e externa.
Viabilidade para a Instalação de um Hotel em Missão Velha-CE
Authors: Santos Rozires Silva dos , Viana Wesley Barros , Costa Netto Manoel Leal
Published: November 2018

O presente estudo procurou como objetivo geral, investigar a viabilidade econômica e financeira de um empreendimento no ramo hoteleiro na cidade de Missão Velha-CE, ponderando as características e dados que se referem ao mercado local, para estabelecer de forma segura as estratégias para a implantação do hotel, sendo realizada a análise de mercado local. De maneira metodológica, foi realizada uma pesquisa de opinião pública com cunho descritivo e exploratório, com abordagem quantitativa. A pesquisa foi aplicada ao público participante entre os dias 06 e 08 de novembro de 2018. Utilizou-se de um questionário com 09 perguntas, distribuídas entre abertas e fechadas. Foram aplicadas por intermédio do Google Forms Questionários. Em seguida com os dados coletados, ocorreu a tabulação pelo auxilio do software Excel. Com resultados obtidos, conclui-se que existe uma viabilidade positiva para a instalação do empreendimento na cidade citada. Percebeu-se também que os clientes desejam qualidade, limpeza, segurança e bom preço nos serviços ofertados pelos hotéis, bem como outros aspectos relevantes, que podem ser usados como diferencial competitivo.
Uso dos Medicamentos Genéricos na População do Município de Aurora-CE, no Período de Janeiro de 2018
Authors: Tavares Luana Fernandes , Carvalho Poliana Moreira de Medeiros
Published: November 2018

A produção de medicamentos genéricos vem crescendo, como também sua utilização, tratando-se de um medicamento que possui o mesmo princípio ativo, composição e ação terapêutica de outra marca que é fabricado por outro laboratório não sendo mais protegido em razão da extinção da patente, tendo o nome de sua substância ativa, sendo utilizado por ser eficaz, seguro e barato. Nesse sentido, o presente estudo teve como objetivo observar a utilização dos medicamentos genéricos em residentes do município de Aurora-CE. Tratou-se de um estudo transversal com a utilização de um questionário estruturado com 100 pessoas residentes na cidade de Aurora-CE com mais de dezoito anos, de ambos os sexos, realizadas as entrevistas nas ruas do centro da cidade, sendo que o instrumento de coleta de dados abrangeu um questionário contendo dados referentes ao uso dos medicamentos genéricos. Quanto à utilização dos medicamentos genéricos em Aurora, foi visto que 58% dos entrevistados têm o hábito de usar medicamento genérico, 57% tendo-os em casa, 69% afirmaram acreditar na sua eficácia e segurança, 79% aceitando a troca do medicamento de referência pelo genérico realizada pelo farmacêutico e 54% comprando genérico não apenas devido o preço ser inferior ao de referência, porém 56% das pessoas não conhecem a diferença entre os medicamentos genéricos, similares e medicamentos de referência, sendo observada a preferência pelos genéricos. Visto que a Política de Medicamentos Genéricos deve divulgar informações sobre o seu uso informando a população, proporcionando aumento do acesso a medicamentos eficazes, seguros e de qualidade, a preços reduzidos.
Gestão Escolar: Assessoria Pedagógica para o Atendimento de Crianças Down
Authors: Dantas Denise Rodrigues , Acosta Juan Pablo Weschollek
Published: November 2018

O tema do presente estudo é assessoria pedagógica para o atendimento de crianças com Síndrome de Down e seu objetivo é determinar as formas de intervenção da gestão escolar para tornar efetiva a inclusão de crianças Down em classes regulares de ensino, sua aprendizagem e desenvolvimento. O tema é abordado com base na realização de pesquisa bibliográfica qualitativa, concluindo que, a gestão escolar, na realidade dos currículos, dos conteúdos e das práticas pedagógicas da educação inclusiva, apesar do processo inclusivo estar ainda em vias de implantação e aperfeiçoamento, pode e deve lançar um novo olhar sobre as possibilidades da educação inclusiva e, especialmente, sobre as crianças Down que ingressam na escola.
Percepção dos Profissionais das Unidades Básicas de Saúde sobre as Práticas Integrativas e Complementares
Authors: Andrade Leonardo Prates de , Morais Karla Cavalcante Silva de , Silva Carla Pequeno da , Tavares Felix Meira
Published: November 2018

As Práticas Integrativas e Complementares em saúde são compostas por um conjunto de atividades e ações terapêuticas, que apesar das políticas nacionais recomendarem sua implementação, é possível observar entre os profissionais de saúde o notório desconhecimento das terapias complementares. O objetivo do estudo foi identificar o conhecimento e opiniões dos profissionais de saúde que atuam nas Unidades Básicas de Saúde sobre as Práticas Integrativas e Complementares. Estudo do tipo exploratório e de abordagem qualitativa. A coleta de informações ocorreu no período de outubro de 2018, por meio entrevistas com os profissionais da UBS. Observou que houveram resultados alarmantes de falta de conhecimento com relação às práticas o que mostrou ser um desafio para sua implementação na atenção básica.
Treating Museum Objects as Text: A Case Study
Authors: Hebert Kirsten
Published: November 2018

Medical instrument collections are neglected primary source material that can be used to produce original scholarship on thehistory of medicine and the history of optometry. Opening museum collections and associated archives to researchers allowscollections managers to simultaneously address curatorial backlogs, facilitate research, and provide a foundation for craftingpublic-facing exhibits. In order to add to the historiography, research should not only focus on the technical aspects of theinstruments, but also employ theory to examine of the meaning of the objects in context. In this way, objects can be a vehicle forunderstanding broader themes in the history of medicine and reveal their utility as material evidence of the impact of medicineon society and culture. This two-part article includes a historiography of ophthalmic instruments and a case study in which an assemblage of ophthalmometers in the Archives & Museum of Optometry collection are treated as “text” to explore the nature of power in the doctor-patient relationship in early optometry.
Sign-Changing Solutions of Fractional 𝑝-Laplacian Problems
Authors: Chang Xiaojun , Nie Zhaohu , Wang Zhi-Qiang
Published: November 2018

In this paper, we obtain the existence and multiplicity of sign-changing solutions of the fractional p-Laplacian problems by applying the method of invariant sets of descending flow and minimax theory. In addition, we prove that the problem admits at least one least energy sign-changing solution by combining the Nehari manifold method with the constrained variational method and Brouwer degree theory. Furthermore, the least energy of sign-changing solutions is shown to exceed twice that of the least energy solutions.
Transforming faces: Supporting second language learners studying speech-language therapy in global contexts
Authors: Bell Nancy
Published: November 2018

The Transforming Faces project is a partnership of speech-language therapy (SLT) educators and practitioners that is co-creating a computer-based series of lecture modules for use in Low Middle Income Countries (LMICs). The initial series of lectures is in English, for use by English speaking instructors and students whose first language is not English. Making the technically challenging and content-specific language of the lectures more accessible and comprehensible to students was the focus of this study. A review of literature from three areas of language learning led to recommendations for consideration in the development of the computer-based lectures modules, and the subsequent piloting of the modules in Addis Ababa, Ethiopia. Following the three-week pilot project, analysis of feedback from the instructor and the students resulted in a number of recommendations for the continued development and implementation of the dysphagia lectures, as well as potential future SLT courses in other global contexts.
Studies of Structural Changes in PAN Fibers with Various Initial Structures under the Influence of Thermal Treatment in Media
Authors: Marczak Ewa , Marczak Piotr , Sztajnowski Sławomir , Lipp-Symonowicz Barbara
Published: November 2018

The aim of the paper is to assess the range and the mechanisms of transformations of the molecular structure and the physical microstructure of polyacrylonitrile (PAN) fibers produced by various manufacturers under the influence of thermal treatment in different conditions. The thermal treatments were carried out in different media (such as air, water, and steam), at various temperatures, and using different periods of treatment. Changes in the molecular structure were assessed using infrared (IR) absorption spectroscopy and evaluation of the differences in molecular cohesion energy of the fiber material during the dissolution processes. Changes in the fibers’ physical microstructure were investigated using densitometric, IR spectrophotometric, and X-ray diffraction methods; for assessment of both the reconstruction process of the paracrystalline matter of the fibers and the changes in the fibers’ total orientation, interferential polarization microscopy was used.
Smart Adaptive Big Data Analysis with Advanced Deep Learning
Authors: Juuso Esko K.
Published: November 2018

Increasing volumes of data, referred as big data, require massive scale and complex computing. Artificial intelligence, deep learning, internet of things and cloud computing are proposed for heterogeneous datasets in hierarchical analytics to manage with the volume, variety, velocity and value of the big data. These solutions are not sufficient in technical systems where measurements, waveform signals, spectral data, images and sparse performance indicators require specific methods for the feature extraction before interactions can be properly analysed. In practical applications, the data analysis, knowledge-based methodologies and optimization need to be combined. The solutions require compact calculation units which can be adaptively modified. The artificial intelligence is extended with various methodologies of computational intelligence. The advanced deep learning approach proposed in this paper uses generalized norms in feature generation, nonlinear scaling in developing compact indicators and linear interactions in model-based systems. The intelligent temporal analysis is available for all indices, including for stress, condition and quality indicators. The service and automation solutions combine these data-driven solutions with the domain expertise by using fuzzy logic for case-based systems. The applications are developed gradually in connections, conversion, cyber, cognition and configuration layers. The advanced methodology is based on the integration of features, scaling functions and interaction models specified by parameters. All the sub-systems and different combinations of them can be recursively updated and optimized with evolutionary computing. The systems adapt to the changing operating conditions and provide situation awareness for the risk analysis. The approach supports different levels of the smart adaptive systems.
Theoretical study of the formation of a spiro-Sn-heterocyclic compound by cycloaddition reaction of Me2C=Sn: and ethene
Authors: Tan Xiaojun , Lu Xiuhui
Published: November 2018

X2C=Sn: compounds (X=H, Me, F, Cl, Br, Ph, Ar) are new species. The cycloaddition reactions of X2C=Sn: are also a new study field of unsaturated stannylene chemistry. The mechanism of cycloaddition reaction between singlet Me2C=Sn: and ethene was investigated for the first time using the MP2/GENECP (C, H in 6-311++G**; Sn in LanL2dz) method. From the potential energy profile, it was predicted that the reaction has one dominant channel in which the 5p unoccupied orbital of Sn: in Me2C=Sn: and the π orbital of ethene form a π→p donor-acceptor bond in an intermediate product. Instability of the intermediate product results in its isomerization to a four-membered ring of stannylene. The four-membered stannylene further combines with ethene to form another intermediate product that further isomerizes to a spiro-Sn-heterocyclic ring compound.
Fuzzy 𝛿-𝐼-continuity in mixed fuzzy ideal topological spaces
Authors: Tripathy Binod Chandra , Ray Gautam Chandra
Published: November 2018

The aim of this paper is to introduce a new concept of fuzzy δ-I-continuity between mixed fuzzy ideal topological spaces and investigate some properties of this mapping.
Predicting Automatic Trigger Speed for Vehicle-Activated Signs
Authors: Jomaa Diala , Yella Siril
Published: November 2018

Vehicle-activated signs (VAS) are speed-warning signs activated by radar when the driver speed exceeds a pre-set threshold, i.e. the trigger speed. The trigger speed is often set relative to the speed limit and is displayed for all types of vehicles. It is our opinion that having a static setting for the trigger speed may be inappropriate, given that traffic and road conditions are dynamic in nature. Further, different vehicle classes (mainly cars and trucks) behave differently, so a uniform trigger speed of such signs may be inappropriate to warn different types of vehicles. The current study aims to investigate an automatic VAS, i.e. one that could warn vehicle users with an appropriate trigger speed by taking into account vehicle types and road conditions. We therefore investigated different vehicle classes, their speeds, and the time of day to be able to conclude whether different trigger speeds of VAS are essential or not. The current study is entirely data driven; data are initially presented to a self-organising map (SOM) to be able to partition the data into different clusters, i.e. vehicle classes. Speed, time of day, and length of vehicle were supplied as inputs to the SOM. Further, the 85th percentile speed for the next hour is predicted using appropriate prediction models. Adaptive neuro-fuzzy inference systems and random forest (RF) were chosen for speed prediction; the mean speed, traffic flow, and standard deviation of vehicle speeds were supplied as inputs for the prediction models. The results achieved in this work show that RF is a reliable model in terms of accuracy and efficiency, and can be used in finding appropriate trigger speeds for an automatic VAS.
Possible hints and pitfalls in diagnosing Peutz-Jeghers syndrome
Authors: Renes Judith S. , Knijnenburg Jeroen , Chitoe-Ramawadhdoebe Sharmila , Gille Johan J.P. , de Bruin Christiaan , Barge-Schaapveld Daniela Q.C.M.
Published: November 2018

Background

Peutz-Jeghers syndrome (PJS) is characterized by gastrointestinal polyposis, mucocutaneous pigmentation and cancer predisposition. Patients with PJS can develop large calcifying Sertoli cell tumors (LCSTs).

Case presentation

A patient presented at 3 years of age with delayed development, hypermobility and later also with tall stature and advanced bone age. Extensive endocrine evaluation, mutation analysis of genes associated with connective tissue disorders and a single nucleotide polymorphism (SNP) array showed no abnormalities. At 8 years of age, gynecomastia developed as well as pigmentations on the lips, both of which are associated with PJS. Mutation analysis showed a heterozygous deletion of the whole STK11 gene confirming PJS. Testicular ultrasound confirmed the presence of LCSTs. Interestingly, the previously performed SNP array did not report deletion of the STK11 gene.

Conclusions

We advise excluding LCSTs in children with tall stature and advanced bone age where more common causes have been eliminated. Although STK11 deletions are documented in control databases, reporting the deletion of this gene even in the absence of a phenotype is advised for patient management.
Hören und Tanzen – Das samāʿ als spirituelles Mittel und gesellschaftliches Kommunikationsmedium
Authors: Küçükhüseyin Şevket
Published: November 2018

The following article looks briefly into the development of the spiritual practice of dance (samāʿ) in Islamic mysticism prior to the ritualization of the dervishes’ ‘dance’ with the early Mawlawiyya. Focusing on changes in the notion of ‘dance’ or physical motion as a consequence of contemplation and ecstasy, it also examines its quality as a means to obtain this state. This is preceded by some remarks on the terms ‘dance’ in Arabic, Persian and Turkish, and a brief discussion of the difficulties of research dealing with medieval dance, primarily in the Turkish context.
Tanzen gegen die Sünde? Zum Tanzkapitel in Meister Ingolds ‚Guldin Spil‘
Authors: Reich Björn
Published: November 2018

In the 15th century, play and dance were expressively criticised. This makes it all the more remarkable for the Dominican Meister Ingold to identify, in his ‘Guldin Spil’, not only chess, cards and dice as some of the seven games useful to overcome the seven deadly sins, but also dance. Ingold, however, does not praise the outward dance. Rather, he intends to turn the reader towards what may be called inner contemplation or Betrachtung, with the various stages of Jesus’ life are transformed into dance steps. The result is an odd conflict: external dance may have negative connotations, yet lays the mental groundwork for the inner Betrachtung. This article aims to explore this area of conflict by examining the various traditions of interpretation which may have influenced Ingold.
Reliability Analysis of Forest Machines Due to FMEA Method
Authors: Ťavoda Pavol , Kováč Ján , Łukaszczyk Zygmunt Ł
Published: November 2018

The article deals with the research of operational reliability of forest felling machines with the method FMEA (Failure Mode and Effect Analysis) and its implementation for observed machines in the organization. Forwarders 810D by John Deere were chosen for this research. The research was realized in real operational conditions. Application of the FMEA method allows flexibility in case of unexpected situations and optimization of human potential abilities. FMEA tool is a tool preventing outages operational reliability and preventive tool for ensuring the maintenance of facilities. This paper explores and verifies the operational reliability theory in practical real-world conditions, resulting in a reduction in operating (variable) costs, minimization of failures and readiness and increased performance of observed machines.
The Optimal Tribotechnical Factors in the Design of Machines – Environmental Element in the Production Systems
Authors: Turis Ján , Beňo Pavel , Biały Witold
Published: November 2018

The article deals with the experimental detection of the tribotechnical parameters for two different types of sliding bearings which are intended for operation without an additional lubrication due to the increasing requirements in ecology and environment. The dominant tribotechnical parameters of the self-lubricating bearing are the coefficient of friction and temperature. To determine these parameters, an experimental method was applied in this paper. The introductory part deals with materials of self-lubricating sliding bearings, their properties and usage. The experimental part consists of the evaluation of friction characteristics and geometric change of a surface after sliding pairs were being worn. Experimental examined sliding pairs comprise a sliding bearing and the shaft. The aim of this research was to determine the effect of radial force on tribotechnical parameters in order to predict the behavior of examined sliding bearings in real operating conditions.
Dual Completion Petroleum Production Engineering for Several Oil Formations
Authors: Ivanova Tanyana Nikolaevna , Korshunov Aleksandr Ivanovich , Koretckiy Vladimir Pavlovich
Published: November 2018

Cost-efficient, enabling technologies for keeping and increasing the reservoir recovery rate of oil-formations with high water cut of produced fluids and exhausted resource are really essential. One of the easiest but short-term ways to increase oil production and incomes at development of oil deposits is cost of development and capital cost reduction. Therefore, optimal choice and proper feasibility study on the facilities for multilayer oil fields development, especially at the late stage of reservoir working, is a crucial issue for now-day oil industry. Currently, the main oil pools do not reach the design point of coefficient of oil recovery. The basic feature of the late stage of reservoir working is the progressing man-made impact on productive reservoir because of water injection increasing for maintaining reservoir pressure. Hence cost-efficient, enabling technologies for keeping and increasing the reservoir recovery rate of oil-formations with high water cut of produced fluids and exhausted resource are really essential. To address the above concerns the dual completion petroleum production engineering was proposed. The intensity of dual completion of formation with of different permeability is determined by rational choice of each of them. The neglect of this principle results a disproportionately rate of highly permeable formations development for the time. In effect the permeability of the formations or their flow rate is decreasing. The problem is aggravated by lack of awareness of mechanics of layers' mutual interference in producers and injectors. Dual completion experience in Russian has shown, that success and efficiency of the technology in many respects depend on engineering support. One of the sufficient criteria for the choice of operational objects should be maximal involvement of oil-saturated layers by oil displacement from seams over the economic life of well producing oil. If it is about getting high rate of oil recovery for irregular formations there is no alternative to dual completion and production. The recommended dual completion petroleum production technology enables development several formations by single well at the time. The dual completion petroleum production technology has been more important than ever because it is right not only for formations but for thin layers with undeveloped remaining reserves.
Options to Use Data Matrix Codes in Production Engineering
Authors: Karrach Ladislav , Pivarčiová Elena
Published: November 2018

The paper deals with the possibilities of using Data Matrix codes in production engineering. We designed and tested the computationally efficient method for locating the Data Matrix code in the images. The location search procedure consists of identification of candidate regions using image binarization, then joining adjacent points into continuous regions and also examining outer boundaries of the regions. Afterwards we verify the presence of the Finder Pattern (as two perpendicular line segments) and Timing Pattern (as alternating sequence of black and white modules) in these candidate regions. Such procedure is invariant to shift rotation and scale change of Data Matrix codes. The method we have proposed has been verified on a set of real industrial images and compared to other commercial algorithms. We are also convinced that such technique is also suitable for real-time processing and has achieved better results than comparable commercial algorithms.
Charitable Support for U.S. National and State Parks Through the Lens of Coproduction and Government Failure Theories
Authors: Gazley Beth , Cheng Yuan (Daniel) , Lafontant Chantalle
Published: November 2018

Substantial public budget constraints across the United States have increased reliance on charities for some public service provision. This article builds a unique historical dataset and presents the first systematic look at the charities supporting U.S. national and state parks through the lens of coproduction along with other major theories of government-voluntary interaction and its consequences. The results suggest that parks-supporting charities are involved in a multi-dimensional pattern of coproduction with distinct and differentiated forms of involvement in public service provision at the state and federal levels. Their growth over time reflects theories of government failure and philanthropic insufficiency. And their permanency suggests the value of greater understanding of public service reliance on private philanthropy.
Applications of metal selenium/tellurium compounds in materials science
Authors: Jain Vimal K. , Kedarnath G.
Published: November 2018

Metal chalcogenides are technologically important materials. Physical, chemical, electrical and mechanical properties of these materials can be fine-tuned by manipulating their shape, size and composition. Although several methods are employed for their synthesis, single-source molecular precursor route has emerged as a versatile strategy for their synthesis and in controlling shape, size and composition of the material under moderate conditions. This chapter gives a brief coverage on the design and development of single-source molecular precursors which have been employed for the preparation of metal selenide/telluride nanocrystals and for deposition of thin films. The discussion includes synthesis of transition-, main group and f-block metal chalcogenolate and/or chalcogenide clusters as precursors and their conversion into metal chalcogenides in the form of thin films and nanostructures. Precursors for ternary metal chalcogenides are also included.