bluuebunny/crossref_metadata_2025 huggingface dataset:
Bibliometric and Visualized Analysis of Global Evolution of Research in Lung
Ultrasound: A Rapidly Developing Field
Authors: Xiao Jinting , Yu Zaiyang , Shang Hao , Dongye Shengzi , Li Shengjie , Wu Jianlin
Published: November 2023

Background::

Lung ultrasound (LUS) is gaining recognition as an indispensable diagnostic tool in critical care.

Objective::

To characterize the global research landscape and trend of LUS with quantification and visualization approaches.

Methods::

Documents related to LUS published between 2007 and 2021 were selected from Web of Science Core Collection and identified. Visualization and statistical analysis were conducted with the VOSviewer 1.6.18, CiteSpace 5.7.R5, and Bibliometrix 4.1.0 Package, including analysis of the trend of global publications, prominent countries, active institutions and funding agencies, key authors and journals, co-cited references, and keywords.

Results::

A total of 2,206 publications including 1796 articles and 410 reviews were retrieved. The output of LUS research has increased steadily over the years, especially after 2018. The United States (n=584; 26.47%) showed the highest output, and the country with the highest total citations was Italy (cited 16567 times). The most influential author was Volpicelli Giovanni with 47 documents, who worked at the San Luigi Gonzaga University Hospital. Chest and Intensive Care Medicine with high citations and impact factor scores were the most influential journals. Besides "lung ultrasonography", the keywords had been developed in "coronavirus disease 2019 (COVID-19)", "acute respiratory distress syndrome (ARDS)", and "acute heart failure".

Conclusion::

Research output has increased steadily at LUS, especially after 2018. The United States and Western Europe are staying ahead in this field. Research collaboration still needs to be strengthened. This comprehensive analysis presents the global research landscape and trends of LUS research, providing valuable information for researchers to pursue further exploration.
Unveiling the ESR1 Conformational Stability and Screening Potent
Inhibitors for Breast Cancer Treatment
Authors: Sharma Khushboo , Panwar Umesh , Madhavi Maddala , Joshi Isha , Chopra Ishita , Soni Lovely , Khan Arshiya , Bhrdwaj Anushka , Parihar Abhyuday Singh , Mohan Vineeth Pazharathu , Prajapati Leena , Sharma Rashmi , Agrawal Shweta , Hussain Tajamul , Nayarisseri Anuraj , Singh Sanjeev Kumar
Published: November 2023

Background:

The current study recognizes the significance of estrogen receptor alpha
(ERα) as a member of the nuclear receptor protein family, which holds a central role in the
pathophysiology of breast cancer. ERα serves as a valuable prognostic marker, with its established
relevance in predicting disease outcomes and treatment responses.

Methods:

In this study, computational methods are utilized to search for suitable drug-like
compounds that demonstrate analogous ligand binding kinetics to ERα.

Results:

Docking-based simulation screened out the top 5 compounds - ZINC13377936,
NCI35753, ZINC35465238, ZINC14726791, and NCI663569 against the targeted protein. Further,
their dynamics studies reveal that the compounds ZINC13377936 and NCI35753 exhibit the
highest binding stability and affinity.

Conclusion:

Anticipating the competitive inhibition of ERα protein expression in breast cancer, we
envision that both ZINC13377936 and NCI35753 compounds hold substantial promise as potential
therapeutic agents. These candidates warrant thorough consideration for rigorous In vitro and In
vivo evaluations within the context of clinical trials. The findings from this current investigation
carry significant implications for the advancement of future diagnostic and therapeutic approaches
for breast cancer.
Enhancing the Bioavailability of Silymarin Phytopharmaceutical by using
Piperine and Fulvic Acid and Simultaneously Quantifying Three
Biomarkers in Plasma
Authors: Ralli Tanya , Saifi Zoya , Usmani Zakiya , Aeri Vidhu , Aqil Mohd. , Kohli Kanchan
Published: November 2023

Background:

Silymarin (SM) is a mixture of seven flavonolignans (FL) and one flavonoid
extracted from the seeds of the milk thistle plant. The major FLs include silibinin, silychristin, silydianin,
and isosilibinin. Silibinin, a mixture of two diastereomers, i.e., silybin A and silybin B, has
been found to be the most active biomarker molecule in the extract of SM. Some studies have also
demonstrated the usefulness of other biomarkers. However, most studies have characterized SM extract
with respect to silibinin only. In our previous study, we isolated five different biomarkers (silychristin,
silibinin, and isosilibinin (mixture of isosilybin A and B)) and denoted them as SM phytopharmaceuticals
(PP). In other research, we have combined the SM PP with two bioavailability enhancers,
i.e., Piperine (PIP) and fulvic acid (FA). The formulation containing 140 mg SM PP, 10%
PIP and 20% FA was optimized using dissolution testing, and its enhanced permeability was demonstrated
by ex-vivo gut sac study and Confocal laser scanning microscopy (CLSM).

Methods:

In this research, we have compared the bioavailability of SM suspension with SM PP and
the optimized formulation in C57BL/6J mice. Furthermore, the bioavailability estimation was done
for three biomarkers simultaneously, i.e., silychristin, silibinin, and isosilibinin.

Results:

Comparing the results for three different groups, it was found that the order of Cmax was F1>
SM PP> SM suspension for all three biomarkers. For all the three biomarkers, the value of Cmax was
at least two times more for F1 as compared to SM suspension. However, the Tmax remained constant
i.e., 2 h for all the three groups and for all the three biomarkers. Furthermore, the clearance values
were found to be in the order SM suspension > SM PP > F1.

Conclusion:

The PIP and FA present in this combination increased the clearance value and Cmax,
respectively, of the formulation. Hence, this combination of SM PP with PIP and FA has shown a
better pharmacokinetic profile than SM suspension, thus, it can serve as a better alternative for the
treatment of liver disease.
Preliminary Study of Antibiotics Susceptibility Testing and Pathogens
Associated with Nosocomial Infections in a Tertiary Hospital
Authors: Tolou-Ghamari Zahra
Published: November 2023

Background:

Health care associated with multiresistant pathogens is rising globally. As nosocomial infections (NIs) could increase hospital stay, morbidity, mortality and disability, therefore the aim of this preliminary study was to define antibiotics and pathogens associated with NIs in a main tertiary hospital in Isfahan, Iran.

Methods:

The data were extracted from the official database of hospital NIs records. For each patient, the reported infections were abbreviated as: UTI-SUTI, VAE-PVAP, BSI-LCBI, SSI-DIP and so on. For continuous variables, mean ± standard deviation, and for categorical varia-bles, frequency was used.

Results:

The study population was 5542 patients, comprised of males (n=3282) and females (n=2260). With a minimum of 15 and a maximum of 99, the mean age in 5313 patients was 58.5 ± 19.1 years old. The highest reported NIs (n= 77%) were associated with the ages between 30-80 years old. Sites of NIs in 93% were as: VAE-PVAP- VAE-IVAC; 31%, UTI-SUTI; 30%, SSI-DIP; 19%, BSI-LCBI; 13%, and other individual infection (7%) with the main pathogens associated with Acinetobacter baumannii, Klebsiella pneumonia, Candida and Staphylococcus spp. Antibiotic susceptibilty testing showed the most sensitivity of isolates against Vancomycin (62%), Gentamicin (59%), Ampicillin (44%), Amikacin (35%) and Co-trimoxazol (32%).

Conclusion:

As most NIs are avoidable, for commissioning an efficient surveillance system, further study of pathogens in relation to evidence-based antibiotic-therapy and advanced infection control program is suggested to be valuable.
Comparative Analysis of Published Database Predicting MicroRNA
Binding in 3’UTR of mRNA in Diverse Species
Authors: Ahirwar Sonu Singh , Rizwan Rehma , Sethi Samdish , Shahid Zainab , Malviya Shivani , Khandia Rekha , Agarwal Amit , Kotnis Ashwin
Published: November 2023

Background:

Micro-RNAs are endogenous non-coding RNA moieties of 22-27 nu-cleotides that play a crucial role in the regulation of various biological processes and make them useful prognostic and diagnostic biomarkers. Discovery and experimental validation of miRNA is a laborious and time-consuming process. For early prediction, multiple bioinformatics data-bases are available for miRNA target prediction; however, their utility can confuse amateur re-searchers in selecting the most appropriate tools for their study.

Objective:

This descriptive review aimed to analyse the usability of the existing database based on the following criteria: accessibility, efficiency, interpretability, updatability, and flexibility for miRNA target prediction of 3’UTR of mRNA in diverse species so that the researchers can utilize the database most appropriate to their research.

Methods:

A systematic literature search was performed in PubMed, Google Scholar and Scopus databases up to November 2022. ≥10,000 articles found online, including ⁓130 miRNA tools, which contain various information on miRNA. Out of them, 31 databases that provide infor-mation on validated 3’UTR miRNAs target databases were included and analysed in this review.

Results:

These miRNA database tools are being used in varied areas of biological research to select the most suitable miRNA for their experimental validation. These databases, updated until the year 2021, consist of miRNA-related data from humans, animals, mice, plants, viruses etc. They contain 525-29806351 data entries, and information from most databases is freely available on the online platform.

Conclusion:

Reviewed databases provide significant information, but not all information is ac-curate or up-to-date. Therefore, Diana-TarBase and miRWalk are the most comprehensive and up-to-date databases.
Políticas regionales de ciencia y tecnología. Capacidades interactivas, redes y desarrollo territorial en dos parques tecnocientíficos de México y Colombia
Authors: Giraldo Palacio María Elena
Published: November 2023

Los parques tecnocientíficos se conciben como instrumentos de política para generar capacidades interactivas entre los actores de la academia, las empresas, el gobierno y la sociedad en una región. Sin embargo, en los países periféricos, donde su implementación es resultado de la emulación de políticas diseñadas en el escenario internacional, esta función ha sido limitada. En este libro se analiza el papel que cumplen dos iniciativas gestadas en las regiones de Yucatán, México y Santander, Colombia. En la investigación se indagó sobre el tipo de capacidades territoriales previas que dieron origen a ambos parques, y las redes de conocimiento que se han dinamizado durante su operación.
Quantum algorithm for ground state energy estimation using circuit depth with exponentially improved dependence on precision
Authors: Wang Guoming , França Daniel Stilck , Zhang Ruizhe , Zhu Shuchen , Johnson Peter D.
Published: November 2023

A milestone in the field of quantum computing will be solving problems in quantum chemistry and materials faster than state-of-the-art classical methods. The current understanding is that achieving quantum advantage in this area will require some degree of fault tolerance. While hardware is improving towards this milestone, optimizing quantum algorithms also brings it closer to the present. Existing methods for ground state energy estimation are costly in that they require a number of gates per circuit that grows exponentially with the desired number of bits in precision. We reduce this cost exponentially, by developing a ground state energy estimation algorithm for which this cost grows linearly in the number of bits of precision. Relative to recent resource estimates of ground state energy estimation for the industrially-relevant molecules of ethylene-carbonate and PF6−, the estimated gate count and circuit depth is reduced by a factor of 43 and 78, respectively. Furthermore, the algorithm can use additional circuit depth to reduce the total runtime. These features make our algorithm a promising candidate for realizing quantum advantage in the era of early fault-tolerant quantum computing.
Imam Mahdi in Sunni Tradition: Differences in Beliefs and Interpretations
Authors: Nur Faisal M.
Published: November 2023

The concept of Imam Mahdi holds a special place, but differences in beliefs and interpretations regarding Imam Mahdi within the Sunni community have led to confusion and even disputes among Muslims. To gain a deeper understanding of how Imam Mahdi is viewed from the perspective of Sunni tradition and the differences in beliefs and interpretations, this research will delve into the complexities of these views and identify different frameworks of understanding. This will help us appreciate the diversity of Islamic thought and how these understandings impact religious practices and the perspectives of Muslim communities. Furthermore, it will underscore the importance of inter-sectarian dialogue in today's increasingly complex Muslim society. The research method employed in this study is a literature review, based on the analysis and synthesis of relevant literature on the specific research topic. Titled "Imam Mahdi in the Perspective of Sunni Tradition: Differences in Beliefs and Interpretations," the findings suggest that al-Mahdi plays a crucial role in elevating the status of Islam and the Muslim community to their true potential. This will enable the Muslim community to shield itself from the negative effects of materialistic modernization and blind imitation of traditions that may not align with Islamic values, as conveyed by the Prophet Muhammad (peace be upon him). The term 'Mahdi' refers to an eschatological figure in Islam, believed to come in the end times to establish justice throughout the world. In the Shia Islamic perspective, Mahdi is the twelfth Imam, and according to their beliefs, he will appear at some point in the future.
Oral Manifestations in Diabetes Mellitus and Management Considerations: A Review
Authors: R. Sonar Dr. Prasanna , S. Panchbhai Dr. Aarati , Mishra Dr. Sunil , B. Dangore Dr. Suwarna
Published: November 2023

Diabetes mellitus is a chronic metabolic disorder defined as an increase in sugar levels in the bloodstream brought onby either insufficient insulin secretion, resistance to insulin's effects, or both. All age groups are affected by the chronic conditionknown as diabetes mellitus. It is among the world's major causes of mortality and morbidity. Xerostomia, dental caries,periodontal disease, gingivitis, candidiasis, other oral infections, burning mouth syndrome, taste dysfunction, oral mucosalalterations, delayed wound healing, and localized osteitis are common oral manifestations of diabetes mellitus. Majorcomplications impacting a patient's quality of life include oral complications in diabetic individuals. Long-term oral problems inthese patients’ harm blood glucose regulation, making oral complications care and prevention important. The dental professionalshould be familiar with DM's oral manifestations to identify this disease complication. This article not only discusses the oralmanifestations but also discusses management considerations in diabetic patients which will help future dental professionals indental practice. This article aims to spread knowledge and awareness about the potential oral manifestations of diabetes mellitusand treatment considerations.Keywords: , , , , ,
Study On Association of Thyroid Hormone and Intensive Care Unit Mortality in Central India.
Authors: Dandekar DrPravin Gulab , Anil Jain Dr Pranay , Jain Dr Shefali
Published: November 2023

Thyroid dysfunction has been linked to mortality in patients hospitalized in the intensive care unit (ICU). We aim tostudy the thyroid hormone level changes in critically ill ICU patients and predict mortality based on thyroid hormone levels. Thisprospective observational study was conducted on 80 consecutive patients aged over 18yrs, from November 2021 to May 2022,in patients admitted to ICU at Chirayu medical college and Hospital, Bhopal, and followed up during their ICU stay. Samples weretested for T3, T4, and TSH on day 1 and day 7. In our study of 80 participants, 46(57.5%) were male, and 34(42.5%) were female.About 32 (40%) were non-survivors. The significance value (P value) of T3 levels on day 1 was 0.083, and on day 7 was 0.001; T4levels on day 1 were 0.85, and on day 7 was 0.001. Similarly, the significance of TSH levels on day 1 was 0.085, and on day 7 was0.001. Day 1 levels of T3 are significantly correlated with APACHE II Score, and Day 7 levels of T3, T4, and TSH significantlycorrelated with APACHE II scores in predicting the outcome of the patients with the higher significance of T3 compared to T4and TSH. Our study showed that low T3 level during critical illness increases mortality risk. Thyroid profiles can be used inpredicting mortality and as an independent factor in predicting the outcome of ICU patients.
Antioxidant and free radicals species in the aqueous humor of patients with age-related cataract
Authors: Brunet Stefan , Babic Nikola , Davidovic Sofija , Miljkovic Aleksandar , Knezi Nikola , Canadanovic Vladimir
Published: November 2023

Introduction/Objective. Age-related cataract is a significant cause of visual impairment worldwide. Oxidative damage and the effects of free radical species are considered important in the etiopathogenesis of cataracts. The aim of this study was to evaluate the antioxidative capacity and oxidative stress in the aqueous humor (AH) according to age and cataracts maturity. Methods. Clinical and biochemical researches were carried out in 55 patients with age-related cataract. According to the cataract maturity, patients were classified into incipient (cortical ? group C, 18 patients; nuclear ? group N, 20 patients; mature ? group M, 17 patients). In order to evaluate the impact of age patients within each group were divided into Group I (65?69 years) and Group II (70 ? years). The antioxidant activity of AH was measured by the reduction power method and the activity of glutathione peroxidase (GPx) spectrophotometrically. Changes in the concentrations of hydroxyl and ascorbyl radicals were detected by electron spin resonance spectroscopy. Results. Both reduction power and GPx activity were significantly (p < 0.001) reduced in group N compared to group C and in group M compared to group N. Concentrations of hydroxyl (29.45 ? 1.01% in group C, 38.12 ? 1.29% in group N, and 74.14 ? 2.52% in group M) and ascorbyl radicals (26.12 ? 0.89% in group C, 41.15 ? 1.39% in group N, and 83.56 ? 2.84% in group M) increased significantly (p < 0.05) with progression of age-related cataract. Significant negative correlation (r = -0.759, p < 0.05) was determined between concentrations of HO? and content of GPx. Conclusion. Our research proved that the level of oxidative stress in the AH is significantly affected during aging and cataract progression, The obtained data support the hypothesis that during aging, depending on the maturity of the cataract, the antioxidant capacity in the AH decreases due to an increase in the concentration of reactive HO?.
La dimensión social de la pandemia: Retornando al trabajo comunitario en la gestión de la pandemia en Navarra
Authors: de la Fuente Hurtado Montse , Abaurrea Leoz Pilar , Lainez Zaragüeta María , Blasco Pérez Maika , Urmeneta Aguilar Santiago , Legarra Zubiria Arantxa , Ibañez Espinal Rocío
Published: November 2023

La progresiva implantación de las acciones previstas en el “Plan Global para el desarrollo de actuaciones sociosanitarias y comunitarias ante la COVID-19 en Navarra” permitió ir aumentando gradualmente la conciencia de que, para una adecuada y más eficaz gestión de la pandemia desde una perspectiva biopsicosocial, no era suficiente con reaccionar ante las necesidades que emergían diariamente, sino que era necesario tratar de anticiparse, o incluso ir un paso más allá con enfoques comunitarios para tratar de incidir en las causas de las causas. Volver al origen desde un modelo salutogénico, centrado más en las fortalezas de las comunidades para generar salud que en el modelo patogénico clásico centrado en controlar comportamientos individuales. Dentro del citado Plan desde el nivel de intervención comunitario, inicialmente se actuó de manera reactiva ante brotes localizados con alta concentración de indicadores de riesgo social en un total de nueve Zonas Básicas de Salud, generando conocimiento útil desde las primeras experiencias a las últimas, llegando a plantear recomendaciones organizativas para facilitar la intervención posterior en esas situaciones. La evolución lógica de estas enseñanzas llevó a avanzar en actuaciones de promoción de la salud mediante la potenciación y facilitación del trabajo con la comunidad a través de las Mesas de Trabajo Comunitario existentes anteriormente o impulsadas durante la pandemia, y a la articulación de redes de sensibilización en determinados puntos del territorio como Tudela.
Angles between matrices and between polynomials in fractional linear systems and electrical circuits
Authors:   Białystok University of Technology, Kaczorek Tadeusz
Published: November 2023

The notions of angles between matrices and between polynomials of fractional linear systems and electrical circuits are proposed. In analysis of angles between state matrices of fractional linear systems the Hadamard product of two matrices is applied. The angles between matrices and their functions are also addressed. The angles between symmetrical and asymmetrical part of matrices are investigated. The angles between polynomials of transfer matrices of fractional linear systems are analyzed and some new properties are established.
Some issues of informational support for multilevel diagnostic systems of electrotechnical equipment
Authors:   Institute of Electrodynamics of the National Academy of Science of Ukraine, Myslovych Mykhailo , Zvarych Valerij ,   Institute of Electrodynamics of the National Academy of Sciences of Ukraine, Ostapchuk Ludwiga ,   Institute of Electrodynamics of the National Academy of Sciences of Ukraine, Hyzhko Yuriy ,   Institute of Electrodynamics of the National Academy of Sciences of Ukraine, Hutorova Мaryna ,   Institute of Electrodynamics of the National Academy of Sciences of Ukraine
Published: November 2023

Algorithmic software for the operation of informational measuring diagnostic systems according to the Smart Grid technology and with the conditional division of the electrotechnical equipment into hierarchical levels is proposed.
Review of the Modern Mongolian Healthcare System
Authors: Neumann Natalie , Warburton David
Published: November 2023

Objectives: Known to most as the horse-loving homeland of Chinggis Khan, Mongolia is today a country of increasing geopolitical, economic, and popular cultural significance. But even as an increasing number of health workers visit the country, its healthcare system remains unexplored in the medical literature. Here follows a broad-brushstrokes overview of the modern medical system of Mongolia, its structure and challenges. It is comprised of an overview of the country’s demographics, health profile, and medical history, followed by a brief summary of selected issues that affect the modern healthcare system. Methods: Descriptive single-case study consisting of clinical observations by the authors, original hospital-level data, and interviews with practitioners and policymakers. Results: The Mongolian healthcare system has performed well through the tumultuous transition from a socialist to a capitalist economy. Our analysis reveals three areas that require improvement: delivery of care, practitioner experience, and health systems administration. Conclusion: This article reviews not only the history and structure of the modern Mongolian healthcare system, but also its strengths and challenges. It is hoped that in explicating these issues, current and future efforts to assist Mongolian health-care providers may be directed more constructively and efficiently.
Diabetes Control in Mongolia: Facts and Needs
Authors: Tumenbayar Bayasgalan
Published: November 2023

No abstract in English
Comparative Study of Ischemic Stroke in Patients Aged Above and Below 50 Years Admitted to a Tertiary Care Hospital in Ulaanbaatar
Authors: Tsagaankhuu Delgermaa , Guntev Tsagaankhuu , Dashjamts Tuvshinjargal , Gongor Baigalmaa , Avirmed Tovuudorj
Published: November 2023

Objectives: The aim of this study was to compare characteristics of ischemic stroke between young (20-49 years) and old (50-89 years) patients undergoing investigations and treatment according to one common protocol in a tertiary hospital. Methods: This hospital-based prospective study included 90 young and 130 old patients with acute ischemic stroke. Data regarding the etiology of the stroke, diagnostic test results and degree of functional improvement of patients were examined during their observation. Results: Common causes for stroke in the young patients were current smoking (53.3%), heavy alcohol consumption (51.1%), cardiac embolism (36.0%), migraine with aura (25.5%), infective diseases (15.6%), and oral contraceptive use (14.4%). Leading causes for ischemic stroke in old patients were the conventional risk factors such as hypertension (75.4%), atherosclerosis (66.9%), and diabetes mellitus (26.9%). Most of the young stroke patients demonstrated good functional outcomes, at the time of discharge (71.1%) and at three weeks (86.6%) according to the Rankin Scale. Conclusion: There are significant differences between young and old patients with ischemic stroke regarding to risk factors, etiological subtypes and improvement of functional deficits associated with the stroke.
Advanced Pharmacology for Prescribers
Authors: Sukhbaatar Sarnai , Dorjsuren Narantungalag
Published: November 2023

No abstract in English
24 February 2022 - for a Geocinematic Use of Found Images
Authors:   CICANT/ Lusófona University, Barata Hugo , Alves Júlio ,   CICANT/ Lusófona University
Published: November 2023

Underlying the idea of precarity and the moving image, this paper describes the and theorizes about the original artwork 24TH FEBRUARY 2022 as a video-installation interconnected with the concepts of precarity in production, circulation, and participation in media culture today, this art-based research artwork tries to underpin the very nature of found material as a gateway from the public to the private, commenting on the spectacle of mass media images and also the production of “anarchival” gestures through which its possible to research a specific historic event. Included in a research project entitled FrameScapes that the authors are undergoing at this time, this research outcome relates to the war that Russia brought again to the gates of Europe when it invaded the Ukrainian territory, and also to the conflict in real-time - live action we could call it - in a way we haven’t seen since Desert Storm back in 1991. A continuous feed of videos and photographs in an era of multi-screen distraction and tiktokian dystopias, artists and creatives have the upper hand in constructing from scratch, just like the cubists would glue together a piece of old newspaper and a matchbox to paint a still-life. The precarious nature of found material to make art is present since the first vanguard movements, from Picasso to Duchamp. Through the arts, we’ve been always confronted with gestures of appropriation, quotation, found-footage, archival art, collage or the ready-made, all of these related to meager images. From Marcel Duchamp to Kurt Schwitters, from Douglas Gordon to Christian Marclay, artists have always looked into the metaphor of the precarious as a recontextualization and remediation of image and sound. The artwork 24TH FEBRUARY 2022 is an exploratory artwork about the world-as-camera-screen, responding critically and creatively to different structures of the social, economic and political contexts in today’s art research practice that deals with found materials. The phenomenon of a tele-visual structure presupposes different atopic tele-communities, built under the aegis of tele-presence and tele-objectivity – a dissolution of real space, that embraces geocinematics as a strong narrative contemporary structure, constructed with and bound by precarious images – images that are consistent with a tangible structure of the Real.
Molar ratio variation on high pressure methanol production: Quantitative safety analysis
Authors:   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Ahmad Mohd Aizad , Abd Rashid Anis Syamimi ,   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Abdul Rashid Zulkifli ,   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
Published: November 2023

The objective of this research was to conduct a quantitative safety analysis as well as estimate the possible risk of deaths due to methanol reactors at the Labuan process facility in Malaysia. The gathered outcomes included scenarios that occurred, such as toxicity, thermal radiation, and overpressure. The percentage of mortality was determined when a chemical mixture was discharged from nine plants in varying ratios of 1:3, 1:7, and 1:10, and at different operating pressures of 76, 184, and 331 bar, resulting in the occurrence of various events. ASPEN Hysys software was used to compute the mass and volume fraction of a chemical mixture. ALOHA and MARPLOT were also used to gather data on toxicity, thermal radiation, overpressure, and impacted zones. The quantity of chemicals emitted was calculated for three distinct leakage sizes (10 mm, 75 mm, and 160 mm). The findings showed that the plant with 331 bars at a ratio of 1:3 had the highest fatality rate of 16.07 %, which was caused by methanol leakage at night for a leakage size of 160 mm. This work has the potential to lower the number of deaths caused by methanol plants.
Peroxide value and palm oil extraction yield from sterilised oil palm mesocarp
Authors:   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Ruslan Siti Zulaikha , Zamanhuri Norashikin Ahmad ,   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia,   Surface Coating Research Group, School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, Selangor, Malaysia
Published: November 2023

Conventional palm oil milling undergoes multiple processes including sterilisation and stripping process that introduce a significant amount of water, resulting in a large amount of wastewater. Sterilisation is the first step in milling, where it is the pre-treatment to deactivate enzymes that increase free fatty acid before oil extraction. Microwave heating softens the surface of the palm fruit mesocarp, making it much easier to extract by solvent extraction. To fill the gap of the previous study, which is to apply two processes of drying and extraction, Soxhlet extraction and microwave will be proposed as an alternative to extracting a higher yield of palm oil mesocarp, replacing the conventional method, which uses the screw pressing process. The power of microwave pretreatment was found to be the most significant factor contributing to poor oil quality. Hence, iodination titration will be used to study the peroxide value (PV) in the oil palm that was extracted. During the sterilisation process, the exposure time and weight of the fruit were constant at 6 minutes and 200 g, respectively. At 800 W of microwave power, without the presence of water, it demonstrated a higher yield, which is around 59.31 %. Peroxide values from sterilized oil palm mesocarp are less than 10 meq/kg; thus, using a microwave sterilisation process followed by the Soxhlet extraction method is an alternative technique to produce crude palm oil.
​​Synthesis of graphene oxide using modified hammers method as fluid loss control additive for water-based drilling fluid (WBDF)​
Authors:   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Nik Ab Lah Nik Khairul Irfan , Wan Zaini Wan Al Harrif Alif ,   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Othman Nur Hidayati ,   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Alias Nur Hashimah ,   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Shahruddin Munawar Zaman ,   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia, Sayuti Muhamad Shafiq ,   School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
Published: November 2023

Water-based drilling fluid (WBDF) is one of the commonly used fluids in drilling operations due to its low cost and environmental advantages compared to oil-based fluid (OBF) and synthetic-based fluid (SBF). The effectiveness of a drilling fluid is mainly dependent on its rheological and filtration properties and these properties are strongly correlated to the type of additives used during the formulation of drilling mud. This study aims to investigate the use of graphene oxide (GO) as a nano-additive in WBDF and evaluate its influence on the rheology and filtration properties of the drilling fluid. Basic rheological properties such as plastic viscosity, yield point, filter cake thickness and density were examined. GO was synthesised using modified Hummer’s method and characterised using x-ray diffractometer (XRD), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analyser (TGA) and scanning electron microscope (SEM) to confirm the properties of GO. XRD analysis shows that graphite was successfully oxidised and exfoliated to GO. The FTIR analysis confirms the presence of C–O, C=C, and O–H bonds in the synthesised GO. The amount of GO added to the WBDF was varied and changes in the rheological properties (density, plastic viscosity, yield point and mud cake thickness) were studied. It was observed that drilling fluid developed using GO has better rheological and filtration properties than drilling fluid formulated without GO. The mud thickness was reduced after the addition of GO, indicating that GO-WBDFs have the capability to control fluid loss into the formation during drilling activities.
A Comparison of Control Schemes for Under-Actuated Pendubot System
Authors:   Ho Chi Minh city University of Technology (HCMUT), Tran Minh-Duc , Pham Le-Tuan-Hung ,   Ho Chi Minh city University of Technology and Education (HCMUTE), Dang Nguyen-Quang-Dong ,   Ho Chi Minh city University of Technology and Education (HCMUTE), Tran Doan-Tuan-Minh ,   Ho Chi Minh city University of Technology and Education (HCMUTE), Nguyen Minh-Khoi ,   Ho Chi Minh city University of Technology and Education (HCMUTE), Bui Le-Anh ,   Ho Chi Minh city University of Technology and Education (HCMUTE), Nguyen Quoc-Khanh ,   Ho Chi Minh city University of Technology and Education (HCMUTE), Vo Minh-Tai ,   Ho Chi Minh city University of Technology (HCMUT), School of Science, Engineering and Technology (SSET), RMIT University Vietnam
Published: November 2023

This paper presents a comparison of the three distinctive well-known control techniques, including Linear Quadratic Regulator (for short, LQR), Sliding Mode Control (for short, SMC), and Fuzzy Logic Control (for short, FLC). Each controller is in a different control category; LQR is an optimal controller employed in both linear and nonlinear systems, SMC is a nonlinear controller commonly applied in a nonlinear system, and the Fuzzy controller is the intelligent controller which can be archived by user’s experiment or other learning techniques. Beside the three main controllers for stabilizing at the equilibrium point, the swing-up controller is designed based on energy-based method to bring the system at the initial position close to the equilibrium points. Finally, the performance and the validity of the three methods are verified through both simulation and experimental results.
ОСОБЛИВОСТІ РЕАЛІЗАЦІЇ ТРЕНУВАЛЬНОГО ПРОЦЕСУ ГІМНАСТОК
Authors: Башавець Наталія Андріївна
Published: November 2023

У статті описано особливості тренувального процесу під час підготовки гімнасток. Окреслено, що гімнастика у її вищій формі – це така модель прояву здібностей та можливостей людини, яка доступна небагатьом особливо обдарованим дівчатам, соціально та морально націленим на цей вид діяльності. Це зумовлює напруженість процесу підготовки гімнасток, диктує закони побудови такої піраміди, основу якої забезпечувало б на її вершині більшу кількість справжніх майстрів гімнастики. У статті наведено науково-методичне обґрунтування системи багаторічної підготовки як цілеспрямованого керованого процесу, який виходить із загальної концепції, яка базується на єдності організаційних, програмно-методичних основ, матеріально-технічної оснащеності процесу та реалізується системним та комплексним використанням специфічних засобів та методів у поєднанні з належним контролем. Окреслено, що мета управління підготовкою гімнасток – це отримання потрібних результатів у необхідний час проведення змагань. Доведено, якщо спиратися на такі закономірності розвитку виду спорту, використовувати прогресивні засоби та методи підготовки, організаційні форми, то можна з повною підставою уникнути стихійного перебігу подій на шляху руху спортсменок до високої майстерності.
Penggunaan Fitur Closefriend Instagram Sebagai Bentuk Self Disclosure
Authors: Sisnawar Widya Cantika , Karimah Kismiyati El , Zein Duddy
Published: November 2023

Latar Belakang: Instagram adalah salah satu media sosial yang sering digunakan saat ini, khususnya oleh generasi milenial usia 18-24 tahun, di dalam Instagram pun terdapat berbagai fitur, salah satunya adalah fitur closefriend. Fitur closefriend merupakan fitur yang memungkinkan penggunanya dapat membagikan berbagai informasi dengan orang-orang yang telah mereka pilih untuk di masukan kedalam fitur tersebut. Tujuan dari penelitian ini untuk mengetahui motif Mahasiswa Bandung-Jatinangor dalam melakukan self disclosure pada fitur closefriend, mengetahui pengalaman Mahasiswa Bandung-Jatinangor dalam melakukan self disclosure pada fitur closefriend hingga bagaimana Mahasiswa Bandung-Jatinangor memaknai self disclosure yang dilakukannya pada fitur closefriend. . Metode yang digunakan oleh peneliti dalam penelitian ini adalah metode fenomenologi, dimana peneliti melakukan observasi, wawancara dan studi kepustakaan untuk mendapatkan data penelitian. Berdasarkan hasil penelitian ditemukan bahwa terdapat faktor yang dapat memotivasi seseorang untuk melakukan self disclosure pada fitur closefriend seperti besaran kelompok, perasaan menyukai, efek diadik, kompetensi, kepribadian, topik dan jenis kelamin. Selain itu setiap individu memiliki tingkat keterbukaan dan batasan privasi yang berbeda-beda. Self disclosure yang dilakukan pada fitur closefriend dilandasi dengan kepercayaan, rasa aman dan nyaman. Fitur closefriend memungkinkan penggunanya untuk dapat lebih berekspresi dan menjadi apa adanya dikarenakan di dalam fitur tersebut hanya berisikan orang-orang yang telah dipercaya. Dengan demikian dapat disimpulkan bahwa fitur closefriend menjadi wadah yang aman untuk melakukan self disclosure. Kata-kata kunci ; Self disclosure; Fitur Closefriend, Instagram, Faktor Self Disclosure, Batasan  privasi
Transcriptome analysis of genes involved in flower and leaf color of Oncidium by RNA-seq
Authors: Wang Ma-Yin , Ding Yu , Zhang Ye , Sun Lu , Song Xi-Qiang , Hao Dai-Cheng , Li Wei-Shi , Tang Min-Qiang , Ling Peng , Xie Shang-Qian
Published: November 2023

Oncidium, an important tropical orchid, has high ornamental value due to its specific color and occupies a significant market position for the worldwide flower. Transcriptome analysis of flower and leaf color formation provides new sources for producing novel Oncidium hybridum cultivars. We sequenced 12 samples of flowers (yellow and white) and leaves (striped and regular) of O. hybridum and assembled 381,136 and 453,566 unigene sequences from RNA-seq data, respectively. Among unigenes, 662 and 1,324 differentially expressed genes were identified in flower and leaf samples, respectively. Gene ontology and pathway enrichment showed that secondary metabolite biosynthetic pathways were responsible for flower and leaf color formation. It was determined that UGT75C1, E2.4.1.115, CCD7, E2.1.1.76, and CCoAOMT are involved in regulating flower color, and UGT75C1, LHCB, UGT, RP-L18Ae, and ABCB1 play crucial roles in regulating leaf color. Kyoto Encyclopedia of Genes and Genomes analysis revealed that UGT75C1 was significantly enriched in the anthocyanin biosynthetic pathway, showing effects on flower and leaf colors. This study was the first detailed analysis of the molecular mechanisms of O. hybridum flower and leaf colors, and the results advanced the understanding of the genetic basis of flower and leaf colors; they also provided additional support for improving commercial value and producing novel cultivars of O. hybridum.
Changes in physical and chemical characteristics of Syrah grapes in response to timing of cluster thinning
Authors: Tahmaz Hande
Published: November 2023

Cluster thinning was performed on vines of the Syrah variety eight days before the véraison (CTBV) and after the completion of the véraison (CTAV) in the 2019 and 2021 vegetation periods. The differences in physiological and chemical properties between the grapes were investigated to which cluster thinning was applied at two different times and those without cluster thinning. According to the research results, CTBV was more effective in the berry fresh weight, dry weight, berry volume, skin weight, skin surface, cluster width, cluster length, cluster weight, and cluster volume parameters than CTAV. Likewise, the levels of total phenolic compounds, total anthocyanins, and antioxidant capacity increased by 9%, 27%, and 30%, respectively, compared to the control group without cluster thinning. Among the phenolic compounds, trans-resveratrol showed the highest increase of 38%, and petunidin-3-glucoside increased the most (12%) among anthocyanins.
Temporal change of soil chemical properties in the southern forest-steppe of the Ufa region of the Republic of Bashkortostan, Russia
Authors: Asylbaev Ilgiz , Khabirov Ilgiz , Khasanov Ayrat , Gabbasova Ilysja , Garipov Timur
Published: November 2023

Modern technologies make it possible to obtain a lot of diverse information about the soil properties using satellite images, but field studies are also required to create or refine digital soil maps. To create a digital soil map scaled 1:25 000 in 2016, a classical field study was conducted with the laying of soil sections in places with the same coordinates as in the mapping of 1982. It allowed to carry out retrospective monitoring of transformation of morphogenetic and agrochemical properties of soils of the southern forest-steppe of the Republic of Bashkortostan (Russia) for the 34-year period of farm use. Thus, the correction and digitization of the soil map allowed to establish that arable land occupies 69.792 ha (67.9%) in the structure of agricultural land (102 811 ha). The monitoring showed deterioration of the main characteristics of arable soil fertility: the diminishing of humus-accumulative horizons, significant decrease of humus content (p ≤ 0.05), a small but reliable acidification of the medium reaction and reducing labile phosphorus. Losses of organic matter occurred mainly in the most fertile soils; their proportion decreased from 55.9% of the total area of agricultural land to 12.4%.
Phytocenological approach in biomonitoring of the state of aquatic ecosystems in Ukrainian Polesie
Authors: Fedonyuk Tetiana P. , Fedoniuk Roman H. , Zymaroieva Anastasiia A. , Pazych Viktor M. , Aristarkhova Ella O.
Published: November 2023

The results of a research into the scale and consequences of the degradation of aquatic ecosystems in Ukrainian Polesie have been detected in article, and the areas of increased anthropogenic pressure have been identified which greatly affect the condition and number of aquatic macrophytes. The biodiversity of sites with different anthropogenic load was evaluated using the biodiversity criteria. In the research, the structural and functional features of macrophytic species diversity within Teteriv River ecological corridor as a typical river landscape of Ukrainian Polesie were determined and described, the floristic composition was determined. Within the ecological zones, the number of species and their projective coverage in areas with different anthropogenic pressures within Teteriv River ecological corridor were determined. The basic criteria for the implementation of deferred biomonitoring based on the analysis of the dynamics of the spe-cies composition of the phytocoenoses of Teteriv River ecological corridor on the indicators of ecological stability and plasticity using the species-specific criteria, are: Margalef species richness index, Sørensen–Dice index, Shannon diversity index, Simpson’s index, and Pielou’s evenness index. Based on the results, correlation dependencies have been constructed, which will allow to obtain data on the stability of the development of aquatic ecosystems according to the data of species surveys. Interconnections between biodiversity indicators and indicators of surface water quality within the Ukrainian Polesie were found; they are the fundamental component of a long-term monitoring of the stability in the development of aquatic phytocenoses.
Waterlogging tolerance: A review on regulative morpho-physiological homeostasis of crop plants
Authors: Sharma Shubhangani , Sharma Jyotshana , Soni Vineet , Kalaji Hazem M. , Elsheery Nabil I.
Published: November 2023

The natural environment is being drastically affected by climate change. Under these severe environmental conditions, the growth and productivity of agricultural crops have reduced. Due to unpredictable rainfall, crops growing in the field are often exposed to waterlogging. This leads to significant crop damage and production losses. In this review paper, the mor-phological and physiological adaptations such as development of aerenchyma, adventitious roots, radial root oxygen loss barrier, and changes in chlorophyll fluorescence parameters of crops under waterlogging are discussed. This will help to understand the effects of waterlogging on various crops and their adaptation that promotes crop growth and productivity. To meet the food requirements of a growing population, the development of waterlogging tolerant crops by screening and plant breeding methods is necessary for plant breeders. Better knowledge of physiological mechanisms in response to waterlogging will facilitate the development of techniques and methods to improve tolerance in crops.