bluuebunny/crossref_metadata_2025 huggingface dataset:
Does human capital mediate the nexus of human resource management (HRM) practices and organizational performance?
Authors: Otoo Frank , Kuar Manpreet , Otoo Evelyn
Published: June 2022

Human capital is a significant element in the attainment of sustained competitive advantage and economic survival of organizations. The study explored whether human capital mediates the nexus of human resource management practices and organizational performance. A field study was conducted among 11 internationally and 4 indigenously owned banks. The hypothesized relationships were supported by the data. The results show that the association between selective staffing with the levels of human capital was significant. The results also show that the levels of human capital influenced organizational performance significantly. The results further show that human capital mediated the nexus of HRM practices and organizational performance. The generalizability of the results obtained may be constrained since the present study focused on the banking industry. The study suggests the creation and maintenance of valuable human capital promote competitiveness and sustained competitive advantage. The study contributes to the extant literature by empirically evidencing that human capital mediated the nexus of HRM practice and organizational performance.
Factors to consider when choosing data collection methods
Authors: Mwita Kelvin
Published: June 2022

Novice and experienced researchers may encounter numerous methodological challenges when it comes to data collection. Data have to be collected from the right sources using appropriate data collection tools to make research studies impactful. There are numerous data collection methods that researchers may use but not all methods are appropriate for all research studies. Choosing inappropriate research methods may result in invalid research findings and lead to erroneous conclusions. This means researchers have to carefully choose data collection methods to make their studies achieve their respective goals. This study intended to identify factors that researchers have to consider in choosing data collection methods. A systematic literature review was used to analyze 28 journal articles published between 2018 and 2022. From the analysis the study identified ten (10) factors that researchers have to consider in choosing data collection methods. These factors are; the research goal, the scope of the study, sample size, type of data, time and user-friendliness to the subjects. Other factors are research approach, safety and security of a researcher, the need for triangulation and theoretical framework. Before choosing methods for data collection, it is important to put into consideration these factors to increase the chances of achieving research objectives and answering research questions of research projects.
Leadership style and organizational citizenship behavior in the local public hospital of Indonesia: The impact of job satisfaction
Authors: Fahriyansyah Mohammad Syahman , Natsir Mokh , Sumarsono Tanto Gatot , Mazaya Sheilla Ulul , Nanang A.S
Published: June 2022

This study aims to explore the mediating role of job satisfaction in the influence of transformational leadership and transactional leadership on organizational citizenship behavior (OCB). A total of 110 respondents were involved in this study. In collecting data, researchers distributed questionnaires to nurses at the regional general hospital, Tulungangung, East Java, Indonesia. The collected data were then analyzed using the partial least squares (PLS) method. The research findings show that there is a significant relationship between transformational leadership and OCB, job satisfaction and OCB. However, not as we expected, transactional leadership did not show a significant improvement in nurses’ OCB. Furthermore, both transformational leadership and transactional leadership are able to act as strong predictors of job satisfaction. Finally, we hypothesized that job satisfaction may mediate the effect of transformational leadership and transactional leadership on OCB.
The impact of knowledge sharing on employee performance at Palangka Raya's health college
Authors: Pakpahan Duma H , Sambung Roby
Published: June 2022

The goal of human resource management research is to establish the impact of LMX on employee performance in health education institutions through job satisfaction and innovation moderated by knowledge exchange. It is critical for an organization's success to be able to apply LMX theory to work satisfaction, innovation, and knowledge exchange. Knowledge Sharing was used as a moderating variable in this study. Employees' inventive behavior is encouraged by the act of exchanging knowledge and collectively developing new knowledge, which involves synergistic teamwork between individuals. Quantitative research was used in this study. Questionnaires were distributed as part of the data collection process. The author enlisted the help of three Palangka Raya-based health education institutions as correspondents. On 75 respondents, data was collected using simple random sampling, and data was analyzed using descriptive statistical analysis and inferential statistical analysis. The findings revealed a link between LMX, innovation, and the moderating of knowledge sharing on performance. As a result of the findings, it is critical to use LMX and innovation in order to boost employee performance.
Evaluation of customer satisfaction attributes on hospitality services
Authors: Otoo Frank Nana Kweku , Effah Ameyaw Godfred , Kuar Manpreet , Otoo Evelyn Akosua
Published: June 2022

Customer satisfaction is an indicator of an organization's overall health and future prospects.  The study evaluated the impact of customer satisfaction attributes on hospitality services. Data were collected from 680 guests of one to three star rated hotels in the Greater Accra Region. The hypothesized relationships were supported by the data. The results show an insignificant relationship between accessibility and hospitability services. Reliability had an insignificant relationship with hospitability services. The results also show that competence had a significant relationship with hospitability services. The results further show that friendliness had an insignificant relationship with hospitality services. The generalizability of the results obtained may be constrained since the present study focused on the hotel industry with its unique characteristics. The study suggests the enhancement of customer satisfaction to establish customer loyalty, improve brand reputation and competitive advantage. The study adds to the extant literature by empirically evidencing that customer satisfaction attributes significantly impact hospitality services.
Social issues faced by children which can be solved through children’s literature
Authors: Mtumane Zilibele , Mojapelo Maishiko Doreen
Published: June 2022

This article discusses social issues faced by children which can be solved through children’s literature. Apart from children’s literature is seen only as a resource for reading, it can also be utilised in solving other societal ills faced by children. These ills include bullying, abuse, family structure and physical impairment. Social challenges are unpacked, detailing how they affect children. Low literacy levels are an issue for many children in South Africa. There are external conditions of learning which may be explained as features outside the learner that influence learning possibilities and are involved in the learning process. These external features are what this article analyze as it has been observed that some of them inhibit the environment for learning, thereby obstructing learning or the required standard of literacy in general.
Challenges faced by female entrepreneurs: The case of the South African learner transport industry
Authors: Mulaudzi Malebo , Schachtebeck Chris
Published: June 2022

This study aimed to explore the challenges faced by female entrepreneurs operating in the learner transport industry in South Africa, specifically in the Gauteng province. The study adopted a qualitative research approach by making use of semi-structured interviews with 15 female entrepreneurs operating in the learner transport industry in the Gauteng province. A non-probability sampling approach was adopted by means of convenience sampling. Data was analysed through thematic content analysis, using Atlas.ti.  Findings from the study indicated that female entrepreneurs in the learner transport industry face several challenges such as high operational costs, a male-dominated industry, being disrespected or undermined by customers, a lack of trust and commitment, being belittled, as well as a lack of opportunity awareness. Participants also indicated a need for government intervention in the industry due to prevailing working conditions. The findings of the study contribute both to the industry, as well as the existing body of knowledge. The findings from the study will assist the national government to collaborate with regional governmental transport agencies, as well as with regional industry associations in an effort to improve the working environment for female entrepreneurs, as well as grow the learner transport industry in a more structured and regulated manner. The industry, despite being regulated by regional transport associations, is currently unstructured.
Online music business: The relationship between perceived benefit, perceived sacrifice, perceived value, and purchase intention
Authors: Sawitri Suraya , Alhasin Alhasin
Published: June 2022

The development of information technology has changed the business model of firms in the industry that are in contact with technology. One of them is in the music industry, which currently has penetrated the online platform with a series of accompanying issues. This study uses a conceptual approach to Technology Acceptance Model to understand this relationship. Although in fact similar research has been carried out by a number of researchers, this topic remains an interesting object to study considering that technology acceptance cannot be separated from the environment in which consumers are located. This research was conducted with a quantitative approach to test the research hypotheses using data obtained from questionnaires distributed to 102 respondents spread across the Yogyakarta area. This study found that perceived usefulness and perceived price do not have a significant influence on perceived value. On the other hand, perceived playfulness and perceived ease of use have a significant influence on perceived value. This finding emphasizes that the online music business is more in touch with entertainment products. With respondents who are dominated by young people in a developing country, it is shown that pleasure is a highly prioritized part of overcoming other considerations, especially price and usability. Another finding is that the greater the perceived value of online music, the higher the intention in purchasing the product would be. This study adds to the literature and information about how consumers respond in different regions (Yogyakarta, Indonesia) as one the developing countries on the factors that affect the perceived value and purchase intention, thus it can be used to test the generality of the results of previous studies.
Migration Risks of the Afghan Crisis
Authors: Shustov A.
Published: June 2022

The hasty withdrawal of US troops and their NATO allies from Afghanistan in August 2021 caused an acute, but local-scale migration crisis. During this crisis, about 200 thousand people were evacuated from the country by the air forces of the Western coalition. The difficult socio-political and economic situation inside Afghanistan after the Taliban seized power poses a threat of a much larger migration crisis. Analogies with the migration consequences of the civil war in Syria, which has been going on since 2011, make it possible to predict the appearance of 8–9.5 million Afghan refugees within a few years who will go to Iran, Pakistan and Central Asia in the event of an aggravation of the internal conflict and further deterioration of the socio-economic situation in Afghanistan. About 1 million of them may end up in Tajikistan, Uzbekistan and Turkmenistan in case of a negative scenario. The appearance of large masses of refugees in Central Asian countries that do not have developed economies will lead to an acute humanitarian crisis. The existence of a visa-free regime between Russia and most of these states will eventually allow immigrants from Afghanistan to freely visit its territory. The penetration of members of radical Islamist organizations based in Afghanistan into the CIS countries is particularly dangerous. The most negative scenario is the spread of a zone of military instability on the territory of Tajikistan, Uzbekistan and Turkmenistan bordering Afghanistan, where about 50 million people live. The destabilization of these states threatens the emergence of mass forced emigration of their indigenous Muslim population to Kyrgyzstan, Kazakhstan and Russia. The negative consequences of these processes will be an increase in the burden on the budget, the education, health and social security systems, the aggravation of terrorist threats, the criminogenic situation and interethnic conflicts. In the long term, mass migration from Central Asia will lead to the transformation of the ethno-confessional structure of Russia, which, in the conditions of depopulation of its population due to the COVID‑19 epidemic, may become irreversible.
Pandemic: Return to the Past or Window into the Future?
Authors: Lapina N.
Published: June 2022

The article analyzes political, social, economic and cultural consequences of the COVID‑19 pandemic for French society. The national strategies of the state management of the sanitary crisis that have developed in the world are investigated: the strategy of “zero tolerance to coronavirus”; the strategy of free circulation of the virus; the strategy determined by the formula “stop and go”. France, like many other Western countries, chose the last one, which implied a combination of harsh measures (lockdown, self-isolation, mandatory vaccination, introduction of sanitary passes) with relaxation caused by the demands of business and society. The increased role of the State in the fight against the pandemic is revealed. The political context of the pandemic crisis settlement is revealed: centralization of power; tight control of the head of state over the activities of the Cabinet of Ministers; dominance of political power over the professional medical community; reduction of the parliament’s role. It is shown that under conditions of the sanitary crisis, the process of informatization of production and services accelerated, significant shifts occurred in the labor market, and there was an increase in social and socio-spatial inequality. The problem of the middle class, which continues to fragment, is acute. The pandemic and especially the methods of combating it caused a protest in French society: the French did not just express disbelief in the effectiveness of the vaccine, with their speeches they demonstrated distrust of the authorities and state institutions. The pandemic has shown that France is in dire need of a new social compromise that would take into account not only the interests of global corporations, but also people who have remained beyond the threshold of the information economy. The issue of reviewing the lowest salaries and raising the status of a number of professions is acute.
A SWOT Analysis of China’s Bid to Join the CPTPP
Authors: Zhang Chong
Published: June 2022

This study aims to discuss the opportunities and challenges of China’s bid to join the CPTPP through a SWOT analysis. Due to the continuous reforms and active participation in international rulemaking, China is getting closer to reaching the CPTPP standards. But to gain the membership of the CPTPP, there are still some impediments to overcome: get the consent of all CPTPP members and meet the high standards, especially those related to cross-border data flows, labor protection, and restrictions on state-owned companies.
Measurement of Trading Strategy Based on Model
Authors: Wang Shiya , Shi Huijie , Zeng Haixi
Published: June 2022

In the changing capital market environment, every trader pursues profit maximization. Based on the historical price of investment products, traders make trading moves that maximize their portfolios.In this paper, several models are established: Model 1: Moving Average Model; Model 2: HPY Model-Calculate the Holding Profit Rate. We also utilized some economic models such as Expected Return on Investment Model to better express our opinions.We use the moving average model, set the moving average, test the optimal moving average cycle by the way of moving average, and assume the two cases of full investment in BTC and gold, judge the buy and sell trading signals of BTC and gold, and get the maximum profit rate. Next, we use the previous evidence. By comparing methods A, B and C, we worked out the situation with the highest return of gold and BTC and formulate investment strategies. In addition, we explain the relevant information of income from the point of view of economics. Finally, we find out that the sensitivity analysis shows that the algorithm has strong robustness in the case that the average model established by us receives changes in the proportion of commission, and has no impact on the strategy made by the model, but affects the results.
Conflict Variety and the Facilitation Role of Forest Managemen Unit (FMU) on Resolution of Tenurial Conflict
Authors:   Universitas Tadulako, Golar Golar
Published: June 2022

In this study, tenure conflict is interpreted as various forms of claims related to mastery, management, utilization, and land use at FMU areas of Dampelas Tinombo. In this context, the FMU will be directly and responsibly involved in addressing disputes in its territory. This research aims to identify and analyze the variety of land-use conflicts and how the role of FMU in resolving conflict resolution in its managed areas. This study was conducted in 2020 at FMU of Dampelas Tinombo using the Rapid Land Tenure Assessment (RA-TA) method. Data collection techniques with a Rapid Rural Appraisal (RRA) approach through in-depth interviews and focus group discussions. The study sample was established by purposive sampling. The results showed that the variety of conflicts in FMU was land clearing, threats of illegal logging activities, and low public trust in programs derived from FMU. The role of KPH is needed in the resolution of tenure conflicts, significantly facilitating in optimizing collaborative management of forest resources and reducing the implementation of social forestry in the form of empowerment schemes and forestry partnerships.
Locals’ Claims of Rights and Access to Forest Resources in Three Forest Management Regimes in Gunungkidul Regency, Yogyakarta
Authors:   Universitas Gadjah Mada, Madjid Muhammad
Published: June 2022

One of state forest areas managed by three management regimes is Bunder forest area, Gunungkidul, Yogyakarta. Three management regimes are the production forest of KPH Yogyakarta, the conservation forest of Tahura, and the educational forest of KHDTK Wanagama I. The differences of management regimes are thought to affect the actual interaction pattern of villagers with the forest. This research aims to compare the actual rights and access of villagers to Bunder forest area in three management regimes in the hope of finding more effective forest management patterns. This research used a qualitative approach through the case study method of the interaction villagers of Bunder, Banaran, Ngleri, and Gading villages with the surrounding forests. The results show that forest management regimes affects the way villagers can access the forests. The aggregate value of the actual rights received by the villagers to the production forest of KPH Yogyakarta is higher than the educational forest of KHDTK Wanagama I. The lowest is management regimes in conservation forest of Tahura. Based on the access mechanisms that empower villagers, the educational forest regime of KHDTK Wanagama I is higher than the production forest regime of KPH Yogyakarta and the conservation forest regime of Tahura. This research recommends defining rights and access to increase certainty about the benefits of forest resources.
Exponentially–Fitted Fourth–Derivative Single–Step Obrechkoff Method for Oscillatory/Periodic Problems
Authors: Wusu Ashiribo Senapon , Olabanjo Olusola
Published: June 2022

The quest for accurate and more efficient methods for solving periodic/oscillatory problems is gaining more attention in recent time. This paper presents the construction and implementation of a family of exponentially–fitted Obrechkoff methods. A single–step Obrechkoff method involving terms up to the fourth derivatives was used as the base method. We also present the stability and convergence properties of the constructed family of methods. Two numerical examples were use to illustrate the performance of the constructed methods.
Novel Multi Epitope-based Vaccine against Monkeypox Virus: Vaccinomic approach
Authors: Shantier Shaza , Mustafa Mujahed , Abdelmoneim Abdelrahman , Fadl Hiba , Elbager Sahar , Makhawi Abdelrafie
Published: June 2022

Background: While mankind is still dealing with the COVID-19 pandemic, on May 7, 2022, a case of monkeypox virus (MPXV) has been reported to the WHO. Monkeypox is a viral zoonotic disease with characteristics comparable to those seen in smallpox cases in the past. It has been a public health threat, particularly in Africa, but recently have been circulating the world, consequently, may become a global public health threat in a very short period. Thus, the current work was planned and then constructed a multi-epitope vaccine that can evoke an immunological response against MPXV utilizing cell surface-binding protein as a target in order to develop a novel vaccine that is both safe and almost free of side effects. Results: The proposed vaccine composed of 304 amino acids and was shown to be antigenic in Vaxijen server (0. 5311) and nonallergenic in AllerTop server. The 3D structure of the designed vaccine is predicted, refined and validated by various in silico tools to assess the stability of the vaccine. Moreover, solubility of the vaccine construct was found greater than the average solubility provided by protein-Sol server indicating the solubility of the vaccine construct. Moreover, the most promising epitopes bound to MHC I and MHC II alleles were found having good binding affinities with low energies ranging between ₋7.0 - ₋8.1kcal/mol. Conclusion: We conclude from our research that the cell surface-binding protein is one of the primary proteins involved in MPXV pathogenesis. The most promising epitopes were selected using a rigorous procedure and used for vaccine design. As a result, our study will aid in the development of appropriate therapeutics and prompt the development of future vaccines against MPXV, which could serve as an important milestone in the production of an antiviral vaccine against MPXV.
Promising Strategies for Preserving Adult Endothelium Health and Reversing Its Dysfunction: From the Liquid Biopsy to New Omics Technologies and Non-invasive Circulating Biomarkers
Authors: Balistreri Carmela
Published: June 2022

The endothelium has multiple functions from maintaining vascular homeostasis, providing nutrition and oxygen to tissues, to evocating inflammation, under adverse conditions, and determining endo-thelial barrier disruption resulting in dysfunction. Endothelial dysfunction represents the typical condition associated with the pathogenesis of all the diseases of cardiovascular system, as well as of diseases of all the other human body’s systems, also including sepsis, acute respiratory distress syn-drome and COVID-19 respiratory distress. Such evidence is leading to identifying potential bi-omarkers and therapeutic targets for preserving, reverting, or restoring endothelium integrity and functionality by early treating its dysfunction. Here, it stresses some strategies for achieving these goals, even if diverse challenges exist and require a significant bench work associated with an in-creased number of clinical studies.
Bifurcation of Solutions of Ornstein-Zernike Equation in the Gas-Liquid Coexistence Region of Simple Fluids
Authors: MENON S.V.G.
Published: June 2022

One objective of this paper is to investigate bifurcation of solutions of Ornstein-Zernike equation in liquid state theory for the gas-liquid coexistence region of simple fluids. The analysis uses a discrete form of the Ornstein-Zernike equation in real space, together with a closure relation which provides nearly self consistent thermodynamic properties of fluids governed by interaction potentials like the Lennard-Jones potential. Accurate asymptotic forms of correlation functions are incorporated in the real space algorithm so as to mitigate the influence of cutoff length used in the discrete approximations. It is found that there is no spinodal on the vapor side on a sub-critical isotherm. But there are fold bifurcation points on the vapor and liquid sides together with a 'no-real-solution-region' in between. This is followed by a region of negative compressibility extending up to the spinodal on the liquid side. The emerging picture is quite similar to that in the case of the hypernetted-chain-closure. It is also found that complex solutions connect the physical solutions that exist outside the 'no-real-solution-region' as well as in region of negative compressibility. The second objective of the paper, in the light of bifurcation scenario, is to evolve an interpretation of the coupling-parameter expansion of correlation functions pertaining to the region of negative compressibility. It is shown that the expansion provides an accurate description of results of the restricted ensembles, implied in mean field theories and simulation methods. Bifurcation of singlet density to inhomogeneous distributions at a spinodal is also established using a simple equation, which uses the direct correlation function. Thus the paper reestablishes the fact that restriction to a homogeneous singlet density is the root cause of all inconsistencies found in the gas-liquid coexistence region.
Impacts of a Statewide Effort to Expand Contraceptive Access in New Mexico, 2014‒2020
Authors: Burapa Wanicha , Martinez Jeremy R. , Daniel Katharine Winkel
Published: June 2022

Two New Mexico state agencies implemented a statewide contraceptive access initiative in a sizable rural border state through the provision of low- or no-cost contraception, provider training and technical assistance, public awareness campaigns, and policy changes. These interventions resulted in successful expansion of reproductive health services provision and contraceptive use among Medicaid-enrolled adolescents and young women of reproductive age between 2014 and 2020. These findings demonstrate how multilevel interventions can expand contraceptive access, even in rural limited-provider settings. (Am J Public Health. 2022;112(S5):S541–S544. https://doi.org/10.2105/AJPH.2022.306817 )
Use of a Learning Community to Expand Access to Contraception
Authors: Estrich Cameron , DeSisto Carla L. , Uesugi Keriann , Akbarali Sanaa , Pliska Ellen S. , Romero Lisa , Cox Shanna , Kroelinger Charlan D. , Velonis Alisa
Published: June 2022

The Increasing Access to Contraception Learning Community was established to disseminate strategies and best practices to support 27 jurisdictions in the development of policies and programs to increase access to the full range of reversible contraceptives. We describe Learning Community activities and identify those that were most useful to participants. Although participation in Learning Community provided jurisdictional teams with structured activities such as virtual learning and peer networking opportunities, some teams struggled with full participation because of staffing turnover and shifts in priorities. (Am J Public Health. 2022;112(S5):S523–S527. https://doi.org/10.2105/AJPH.2022.306823 )
Sheared and Granular Peridotites from the Udachnaya–East Kimberlite (Yakutia): Mineralogy, Chemistry, and PGE Patterns
Authors: Ilyina O.V. , Agashev A.M. , Pokhilenko L.N. , Kozhemyakina E.A. , Pokhilenko N.P.
Published: June 2022

—Mantle xenoliths of fresh sheared and granular peridotites from the Udachnaya kimberlite pipe (Yakutian kimberlite province, Siberia, Russia) are studied in terms of mineralogy, chemistry, and behavior of platinum-group elements (PGE), with a focus on difference between the two types of peridotites and on the role of PGEs in their origin. The analyzed samples of sheared and granular peridotites differ in mineral-liquid equilibrium temperatures and pressures: 1230–1350 °C, 56–67 kbar inferred for the former and 750–1300 °C, 30–67 kbar for the latter. The contents of major oxides, trace elements, and PGEs differ both between sheared and granular peridotites and within each group. Some sheared and all granular peridotites are enriched in incompatible elements, have low percentages of clinopyroxene and contain garnet rich in middle rare-earth elements (MREE). These features result from interaction of the peridotites with melts and related fluids of presumably carbonate compositions containing incompatible elements in high abundances. Sheared peridotites were more strongly enriched and gained more Ca, Al, and Ti than the granular variety. On the other hand, granular peridotites have higher light REE (LREE) and lower heavy REE (HREE) enrichment, which may record compositional difference of metasomatic agents. Metasomatism acted in two stages: first silicate agents caused LREE enrichment and HREE depletion of melts and then the fractionated melts percolated through the mantle and affected the compositions of granular peridotites and, partly, sheared peridotites. The two types of peridotites differ also in PGE patterns, with largely variable Os–Pt concentrations in granular peridotite. This difference may be due to uneven distribution of the Os–Ir and Pt–Os–Ir intermetallic compounds, which formed as sulfide melting residue in the lithospheric mantle. Sheared peridotites show almost uniform Os–Pt distribution and are enriched in Pd, Re, and partly Pt. The enrichment possibly occurred during metasomatism when the percentages of garnet and clinopyroxene increased while sulfide phases precipitated into interstitials.
The e-mental health treatment in Stockholm myocardial infarction with non-obstructive coronaries or Takotsubo syndrome study (E-SMINC), a study protocol for a randomized controlled trial
Authors: Olsson Erik Martin Gustaf , Norlund Fredrika , Rondung Elisabet , Humphries Sophia Monica , Held Claes , Lyngå Patrik , Spaak Jonas , Sundin Örjan , Sundelin Runa , Leissner Philip , Kövamees Lena , Tornvall Per
Published: June 2022

Background:
In the aftermath of a myocardial infarction with non-obstructive coronary arteries (MINOCA) or Takotsubo syndrome (TS), patients commonly express high levels of stress and anxiety. Current treatment alternatives rarely address these issues.
Methods:
The study is a randomized controlled trial, where 90 patients with a discharge diagnosis of MINOCA or TS who also report symptoms of stress or anxiety will be randomized 2–4 weeks after their cardiac event. The treatment consists of ten weeks of internet-based cognitive behaviour therapy (CBT) and starts immediately after randomisation for the treatment group. The control group receives usual care. Main outcomes are symptoms of anxiety measured with Hospital Anxiety and Depression scale, Anxiety subscale and perceived stress measured with the Perceived Stress Scale, 14 item version, ten weeks after randomisation. Secondary measures include cardiac specific anxiety, symptoms of post-traumatic stress, quality of life, cortisol measured in hair and physiological stress responses (heart rate variability, blood pressure and saliva cortisol) during a stress procedure. Ten weeks after randomisation the control group will also receive treatment. Long-term follow up in the self-report measures mentioned above will be conducted 20 and 50 weeks after randomisation where the total group’s development over time is followed, and the groups receiving intervention early versus late compared.
Discussion:
At present there are no randomised studies evaluating psychological treatment for patients with MINOCA or TS. There is an urgent need for treatment alternatives aiming at relieving stress and anxiety considering the high mental stress and anxiety levels observed in MINOCA and TS, leading to decreased quality of life. CBT aiming at reducing mental stress has been shown to be effective regarding prognosis in patients with coronary artery disease. The current protocol describes a randomized open-label controlled trial evaluating an internet-based CBT program for reduction of stress and anxiety in patients with increased mental stress and/or anxiety with a discharge diagnosis of either MINOCA or TS.
Trial registration:
Clinicaltrials.gov NCT04178434. Registered 26 November 2019, https://clinicaltrials.gov/ct2/show/NCT04178434
A Long-term Global Comparison of IMERG and CFSR with Surface Precipitation Stations
Authors: Ghimire Uttam , Akhtar Taimoor , Shrestha Narayan , Paul Pranesh , Schürz Christoph , Sriniva Raghavan , Daggupati Prasad
Published: June 2022

For data sparse conditions of developing countries, gridded meteorological products have potential for different hydro-climatic applications. Comparisons of IMERG precipitation, at 0.1o, have been done with TRMM precipitation at station-, basin- and country-scale, in recent past. As IMERG products are expected to be available at least until mid-2030, a long-term global comparison of IMERG precipitation at station-scale, to guide their potential use, is highly desired. Therefore, we access surface precipitation stations from NOAA and compare their GSOM with IMERG at 0.1° during 2001–2020. Thus, we evaluate mean IMERG, CFSR and GSOM monthly precipitation with standard metrices like NSE, VE, KGE, R, RMSE and PBIAS for 5 geographical regions, 7 continents, 105 countries and > 50,000 surface locations. After comparison, we observe highest median NSE for Tropic of Capricorn (IMERG: CFSR = 0.85:0.59), followed by Antarctic (0.76:0.49), Arctic (0.71:0.32), Tropic of Cancer (0.64:0.14) and Frigid circle (0.47: -0.87). It shows satisfactory and unsatisfactory performances in the ‘fourth/first’ and ‘last/remaining regions’ for ‘IMERG/CFSR’, respectively. Fractional similarity of unit precipitation was good in Europe (VE = 0.72), North America (0.72), Asia (0.71), Australia (0.70) and satisfactory in South America (0.66) and Africa (0.52) for IMERG. Whereas, we find satisfactorily simulation for Europe (VE = 0.61), North America (0.56) and Australia (0.56), while other continents have unsatisfactory simulation of precipitation by CFSR. At country levels, 64 countries reveal a significantly better mean NSE with IMERG. While all these analyses pointed that IMERG monthly precipitation has better utility than CFSR in different hydro-meteorological applications, its site-specific application will still need detailed analysis at daily (sub-daily) resolutions. The outcomes of the study are expected to guide water resources managers to use these datasets in sustainable water resources management.
A Three-Dimensional Paradigm for the Onset of Fluid Turbulence
Authors: Rathmann Carl
Published: June 2022

A detailed and physically correct model of the origins of the fluid transition from laminar to turbulent flow has long evaded engineers, and designers have necessarily utilized simplified approaches, numerical models, and conservative assumptions. With the hope of formulating an easily understood and more accurate paradigm of the onset of turbulence, this paper proposes and elaborates on the “Modal Bifurcation Model” (MBM) as a new manner of describing the three-dimensional growth of turbulence in steady-state flows. The model proposes that the onset of turbulence is the manifestation of concurrent and interlinked bifurcating modes in velocity, pressure, and temperature in the flow with increasing Reynolds number. After summarizing the set of governing equations of fluid dynamics, the paper compares the relative roles played by the linear and non-linear terms in the equations, and re-formulates the set utilizing three-dimensional orthogonal function expansions. The paper investigates the excitation and concurrent bifurcations of orthogonal modes, and identifies simple and predictable patterns of the appearance and growth of all modes. The work reported here: confirms that the non-linear terms of the governing equations necessarily involve bifurcation phenomena that spread throughout the flow by mode coupling; reverses the historically assumed order of modal appearance as turbulence initially develops; verifies the supposition that first modal bifurcations appear in an identifiable order and, hence, are predictable; and suggests that the onset of turbulence can potentially be delayed in specific applications through mode-specific damping.
Internet Addiction and Relationships with Depression, Anxiety, Stress and Academic Performance among Egypt Pharmacy Students: A Cross-Sectional Designed Study
Authors: Sayed Moustafa , Medhat Christina , Aboelsaad Marina , Ibrahim Michael
Published: June 2022

Background and Aims
Pharmacy students represent the future of healthcare professionals and with daily use of the internet for different activities has made internet addiction (IA) of a growing concern. The main objectives of this study were to 1) assess internet addiction among pharmacy undergraduate students as well as factors associated with it; 2) assess the relationships between internet addiction and common mental disorders (depression, anxiety, and stress), in addition to academic performance and body mass index factors.
Methods
We utilized a cross-sectional questionnaire that was conducted among 808 students of Egypt university pharmacy students across the country. The surveys used included: Young Internet Addiction Test (YIAT) and the Depression Anxiety Stress Scales (DASS 21).
Results
YIAT average score was 44.75 (19.72%); prevalence rate of potential IA was 311 (38.5%) with no gender significant difference. We couldn’t detect any type of correlation between potential IA, stress, anxiety, depression and GPA. However, a robust correlation was found between internet addiction vs depression, anxiety and stress collectively.
Conclusions
Internet addiction is usually associated with mental related disorders thus it is of paramount important to identify it among students. Different therapeutic interventions could include management to IA and common psychological disorders such as depression, anxiety, and stress.
A Thermal Aware Application Mapping Algorithm for Photonic networks-on-chip
Authors: Ghafori Arash , reza akram , Mirzaee Reza Faghih
Published: June 2022

Photonic Network on Chip(PNoC) is a promising solution to overcome scalability and power consumption challenges in the traditional Network on Chip(NoC), with high bandwidth and low latency communication. Thermal sensitivity is one of the main problems in PNoC network. Because of the thermal sensitivity of photonic devices, thermal effects can cause the operation becomes incorrect or inaccurate, same as Laser power efficiency degradation, wavelength shifting, power loss due to wavelength mismatch, and switching disorders. Therefore, the goal of this study is set to present a suitable new mapping algorithm, which aims to Thermal distribution and maximum reduction thermal of PNoC. The main parameter that affects power consumption and thermal is a maximum power loss, maximum number of WDM channels and maximum communication thermal correlation. By increasing the amount of maximum power loss and the maximum number of WDM channels, the power of the signal in the source must be increased, which leads to an increase in thermal PNoC. In this paper, we modelled thermal parameters and suggested a fitness function to evaluate application mapping algorithms based on genetic algorithms. Based on evaluation results, the minimum thermal improvement is 23% in GA mapping with different W Coefficient and 46% improvement compared to the Nmap algorithm.
Free water diffusion MRI differentiates suicide ideators from attempters with treatment-resistant depression
Authors: Vandeloo Katie , Burhunduli Patricia , Bouix Sylvain , Owsia Kimia , Cho Kang Ik Kevin , Fang Zhuo , Geel Amanda Van , Pasternak Ofer , Blier Pierre , Phillips Jennifer
Published: June 2022

Suicide attempt is highly prevalent in treatment-resistant depression (TRD), however, the neurobiological profile of suicidal ideation versus suicide attempt is unclear. Neuroimaging methods including diffusion MRI (dMRI) based free water imaging may identify neural correlates underlying the progression from suicidal ideation to attempts in individuals with TRD. dMRI data were obtained from 64 participants, including 39 patients with TRD (n=21 suicide ideators and n=18 suicide attempters), and 25 age- and sex-matched healthy controls. Depression and suicidal ideation severity were examined using clinician-rated and self-report measures. Whole-brain analysis of neuroimaging data was conducted using tract-based spatial statistics via FMRIB Software Library to identify between-group differences in white matter microstructural integrity in suicide ideators versus attempters, and in patients with TRD versus controls. Free water imaging revealed elevated axial diffusivity (AD) and extracellular free water (FW) in fronto-thalamo-limbic white matter tracts of suicide attempters compared to ideators (thresholded p<0.05, FWE corrected). In a separate comparison, patients with TRD were found to have widespread reductions in fractional anisotropy (FA) and axial diffusivity (AD), as well as elevated radial diffusivity (RD) compared to healthy controls. A unique neural signature consisting of elevated AD and FW is identified for the first time in suicide attempters with TRD. Findings of reduced FA, AD, and elevated RD in patients versus controls are consistent with previously published studies. Multimodal and prospective investigations are recommended to better understand biological correlates of suicide attempt.
Comprehensive study of the occurrence and characteristics of carbon, nitrogen, and phosphorus in sediments and riparian soils of large drinking water reservoir
Authors: Hu Shuanggang , Cui Kangping , Chen Yihan , Hassan Muhammad
Published: June 2022

The contamination of nutrients has caused considerable worry about the environment, resource value, and ecological worth of drinking water reservoirs. Therefore, we comprehensively studied the abundance, sources, distribution, and environmental behavior of carbon, nitrogen, and phosphorus in Fengshuba Reservoir (FSBR) (a large drinking reservoir, China). Seasonal hydrological circumstances had little influence on the nutrient abundance and structural component of the FSBR, while carbon, nitrogen, and phosphorus abundance, composition, and environmental behavior varied significantly between various environmental media (sediment and soil phases). Microbial-derived humus (C1), terrestrial-derived humus (C2), and protein-like tryptophan (C3) were identified as the three primary fluorescence components using parallel factor analysis. The abundance of colored dissolved organic matter (CDOM), molecular weight, aromatization degree, and humification degree of dissolved organic matter (DOM) in the sediment were lower than in the soil, whereas the authigenic component was greater than in the soil, according to spectral index analysis. The main sources of humus in FSBR were biogenic contributions. Principal component analysis indicated that three components were closely associated to phosphorus in the sediment phase, whereas nitrogen and phosphorus in the soil phase were mainly related to C1 and C2. In summary, in the management and control of water environment nutrients in reservoirs, soil media in the riparian zone must be carefully considered.
MicroRNA-sequencing Analysis of Plasma-derived Exosomes Provides Novel Insights into the Disease Mechanism of Childhood Atopic Dermatitis
Authors: Zhu Teng , Sun Jing , Tian Jing , Liang Yuan , Ma Lin
Published: June 2022

Background: Exosomes are nano-size vesicles that plays important roles in transporting cellular modulators including microRNAs (miRNAs), DNA and proteins between cells. Exosomes and their components are proved to implicate a variety of dermatologic disorders in adults. However, the expression pattern of exosomal miRNAs in pediatric atopic dermatitis (AD) patients has not been well studied. Methods: Plasma samples were drawn from 5 pediatric AD patients and 5 age-matched healthy volunteers. Small RNA sequencing was performed to identify differentially expressed exosomal miRNAs (DEPEMs) between those two groups. Bioinformatics tools including Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were used to explore the DEPEMs involved canonical pathways and their relationships with the pathogenesis of AD. Reverse transcription real-time polymerase chain reaction (RT-qPCR) was used for validation and measurement of DEPEM levels. Results: A total of 40 DEPEMs, including 29 upregulated and 11 downregulated DEPEMs, were identified. Using the miRanda and TargetScan databases, 17,238 target genes of the 40 DEPEMs were predicted. GO and KEGG pathway enrichment analyses suggested that these target genes were involved in multiple functions and pathways associated with AD, such as the skin barrier, T-cell differentiation and keratinocyte proliferation. 10 selected DEPEMS, including 5 downregulated miRNAs (hsa-miR-1343-3p, hsa-miR-301a-5p_R-1, hsa-mir-1273c-p3, hsa-miR-374b-3p and hsa-miR-1908-5p) and 5 upregulated miRNAs (hsa-let-7b-3p_R-1_1ss21CT, hsa-miR-34a-5p, hsa-miR-100-5p_R-1, hsa-miR-27a-5p and hsa-mir-3976-p3_1ss16AT) were verified through RT-qPCR. Conclusions: This study provides the first genomic profile for understanding the pathogenesis and potential biomarkers for pediatric AD patients. The DEPEMs from our study differs from those from adult AD patients, suggesting children with AD have distinct peripheral exosomal miRNA expression. DEPEMs may serve as promising novel biomarkers or regulators of pediatric AD pathology.
The effects of Mediterranean diet on cardiovascular risk factors, glycemic control and weight loss in patients with type 2 diabetes: A meta- analysis
Authors: Zheng Xing , Zhang Wenwen , Wan Xiaojuan , Lv Xiaoyan , Lin Peng , Si Shucheng , Xue Fuzhong , Wang Aijun , Cao Yingjuan
Published: June 2022

To explore the impact of the Mediterranean diet on cardiovascular risk factors, glycemic control and weight loss in patients with type 2 diabetes(T2D) by a meta-analysis of randomized controlled trials (RCTs). We systematically searched PubMed, Cochrance Library, EMBASE and four Chinese databases to identify RCTs that compared the Mediterranean diet with control diets in patients with T2D up to December 2021. The Risk of Bias of the included studies was assessed using the version 2 of the Cochrane risk-of-bias tools for randomized trials (ROB 2). Seven RCTs with 1371 patients met the eligibility criteria and entered into the meta-analysis. Compared to control diets, the beneficial effects of Mediterranean diet were not statistically significant in high-density lipoprotein (MD = 2.33; 95% CI: -0.27 to 4.92), low-density lipoprotein (MD -2.34; 95% CI -5.67 to 0.99) and total cholesterol (MD = 2.92; 95% CI: -0.84 to 6.67). But Mediterranean diet led to reduce the level of systolic blood pressure (MD = -1.20; 95% CI: -2.21 to -0.19) and diastolic blood pressure (MD = -4.17; 95% CI: -7.12 to -1.22). Meanwhile, Mediterranean diet showed beneficial effects in glycemic control (HbA1[%]:MD = -0.39, 95% CI: -0.58 to -0.20; fasting plasma glucose: MD = -15.12 mg/dl, 95% CI: -24.69 to -5.55mg/dl) and weight loss (BMI: MD = -0.71, 95% CI: -1.30 to -0.78; MD = -1.69; 95% CI: -3.35 to -0.02) compared to the control diets. The meta-analysis provided evidence the Mediterranean diet showed the beneficial improvements in blood pressure glycemic control and weight loss, but the effect of Mediterranean diet on lipid profile was not significant, which needed further verification.