bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of CD24 as a potential biomarker for malignant pleural mesothelioma
Authors: Mousa Mohamed Shaaban , Ghoname Ahmed Mamdooh , Ateya Dalia Abd El-Kareem , Abdallah Hamed A H , Ahmed Salwa Hassan
Published: November 2023

Objectives

Pleural mesothelioma is a rapidly progressing pleural neoplasm caused by asbestos exposure of a long latency around 30-40 years. Patients with mesothelioma are usually diagnosed at a late stage with poor outcomes in terms of morbidity and mortality with 6–12 months’ median survival. Despite the prohibited use of asbestos, malignant pleural mesothelioma is still increasingly being occurred in young age and female patients. Different un-standardized biomarkers have been used to diagnose MPM as mesothelin and febulin with controversial results, so we used CD 24 as a biomarker to diagnose and differentiate between different subtypes of malignant pleural mesothelioma.

Materials and methods

Our cohort study included total of fifty-nine patients with exudative pleural effusion. All patients underwent full history taking, clinical examination, blood tests (CBC, coagulation profile, liver and kidney functions), tapping of pleural effusion and to send pleural fluid investigations for LDH, albumin, total protein and albumin, then confirmed exudative pleural effusion patients were subjected to thoracic ultrasonography and medical thoracoscopy for the majority of cases or ultrasound guided biopsy in selected cases to obtain pleural biopsies for histopathology and then the examination of pleural biopsies for CD24 expression.

Results

Our study demonstrated the possibility of using CD24 as a biomarker in the immunostaining of pleural biopsies to differentiate between malignant pleural mesothelioma and pleural malignancy other than mesothelioma (18 mesothelioma cases versus 2 nonmesothelioma malignant cases) with high statistical significance P value < 0.001 and also it can discriminate between subtypes of mesothelioma as it showed marked significance in epithelioid subtype (12 epithelioid versus 1 sarcomatoid versus 5 biphasic subtypes) with more uptake by score +2 in epithelioid mesothelioma.

Conclusions

CD24 can be supposed to be a routine biomarker for immunohistochemistry of pleural tissue samples in diagnosis of mesothelioma and it can be used to differentiate between subtypes of malignant mesothelioma subtypes.
Comparison between thoracoscopic pleural cryobiopsy and conventional forceps biopsy in diagnosis of exudative pleural effusion: Assiut University experience
Authors: El-Morshedy Reham M , El-kholy Maha M , Kamel Nermeen A M H , Sadek Samiaa H , Abdel Ghany Alaa S , Mohamed Marwan N
Published: November 2023

Context

Exudative pleural effusion is a diagnostic dilemma that includes many steps; one of them is obtaining a definite diagnosis through pleural biopsy.

Cryoprobes are being increasingly used for obtaining larger specimens with fewer crush artifacts. However, the safety and feasibility of cryoprobe biopsy compared with standard forceps for pleural biopsy have not been fully assessed.

Aims

To evaluate the diagnostic value, size, and quality of the specimens obtained by flexible cryoprobe in comparison with those obtained by flexible forceps probe during medical thoracoscopy in patients with exudative pleural effusion and to assess the possible complications from the procedure.

Settings and design

This interventional prospective study was carried out at the endoscopy unit at Chest Department and Tuberculosis Assiut University Hospital.

Patients and methods

This study included 60 patients with undiagnosed exudative pleural effusion. Medical thoracoscopy was carried out for all the patients, and pleural biopsies were taken from the parietal pleura using a conventional rigid forceps probe and flexible cryoprobe in the same settings.

Results

Cryoprobe biopsy established a definite diagnosis in 55/60, with 91.6% diagnostic yield, whereas forceps biopsy had a definite diagnosis in 53/60, with 88.3% diagnostic yield.

The size of cryoprobe biopsy was significantly larger in comparison with the forceps biopsy (26.56 ± 22.16 vs. 17.38 ± 12.08 mm2; P<0.001). The depth of pleural biopsy was evaluated by the presence of extrapleural fat cells, which were significantly higher in cryoprobe biopsy in comparison with forceps biopsy [21 (35%) vs. 11 (18.3%); P=0.03]. There were no significant complications or procedure-related deaths.

Conclusions

Cryobiopsy is a possible safe and effective alternative to conventional forceps probe biopsy in the diagnosis of exudative pleural effusion with a larger, deeper, and less number of biopsies. It was also found that cryoprobe biopsy had a better diagnostic yield, sensitivity, and accuracy.
Transthoracic ultrasound in the diagnosis and follow-up of ventilator-associated pneumonia
Authors: El-shinnawy Olfat M , Metwally Mohamed , Abdelaleem Nermeen , R R Gharieb Dina
Published: November 2023

Context

Patients in the intensive care unit (ICU) are at risk not only from their critical illness but also from secondary processes such as nosocomial infection. Pneumonia is the second most common nosocomial infection in critically ill patients. Indeed, diagnosis of ventilator-associated pneumonia (VAP) requires a high clinical suspicion combined with bedside examination, radiographic examination, microbiological analysis of respiratory secretions, and blood test.

Aims

This study aimed to evaluate the effectiveness and accuracy of lung ultrasound for VAP diagnosis and follow-up.

Settings and design

A prospective cohort study was conducted on 74 patients, with a total number of 54 with a high likelihood of VAP and 20 with a low likelihood of VAP.

Methods and material

Mechanically ventilated patients for 48 h or more were included. We calculated the clinical pulmonary infection score and the lung ultrasound was performed within 24 h.

Statistical analysis

Data were collected and analyzed using SPSS (Statistical Package for the Social Sciences, version 20, IBM, and Armonk, New York). Quantitative data were expressed as mean ±standard deviation (SD) and compared with Student’s t-test. Nominal data were given as number (n) and percentage (%). Chi2 test was implemented on such data.

Results

Based on the clinical pulmonary infection score (CPIS) with a cutoff point of ≥6, the sensitivity of transthoracic ultrasound was 81.5%, the specificity was 82%, and the accuracy was 81.6%. Regarding sonographic signs, the highest sensitivity was for subpleural dots of consolidation (82%), then B-lines (56%), followed by pleural effusion, and air bronchogram (both 19%). The highest specificity was for air bronchogram (100%), then B-lines, and pleural effusion (both 90%), followed by subpleural dots of consolidation (80%). The positive predictive value for transthoracic ultrasound was 92%; the area under the receiver-operating characteristic (ROC) curve (AUC) for the total ultrasound score was 0.82.

Conclusions

Transthoracic ultrasound is an easy bedside tool for the diagnosis and follow-up of ventilator-associated pneumonia.
Glucagon in the gut – brain axis
Authors: Parikh Rakesh M , Saboo Banshi , Mohan Viswanathan , Basit Abdul , Gupta Amit , Panda Jayant K , Bhartia Mithun , Topsever Pinar
Published: November 2023

The intricate relationship between the gut and the brain has long captured the imagination of scientists, philosophers, and clinicians alike. Over the past few decades, research has unveiled a complex and bidirectional communication network that connects these seemingly distinct organs, giving rise to the concept of the gut–brain axis. This axis represents a dynamic and multifaceted system through which the gut and the brain exchange signals, impacting not only digestive processes but also a wide array of physiological and neurological functions. From influencing appetite and mood to playing a role in metabolic regulation, the gut–brain axis has emerged as a crucial nexus in understanding human health and well-being. This chapter delves into the intricate mechanisms that underlie the gut–brain axis, exploring its components and pathways with a special focus on the role played by glucagon. By unraveling the mysteries of this axis, we gain valuable insights into how our body’s diverse systems collaborate to maintain a delicate balance and how disturbances within this axis can contribute to a range of health conditions.
Glucagon receptor modulation: Its role in diabetes care
Authors: Seshadri Krishna G , Sosale Aravind R , Prasanna Kumar Kanakatte M , Reddy Sanjay C , Chawla Purvi
Published: November 2023

The metabolic changes attributable to diabetes are due to both deficiency of insulin as well as excess glucagon (GC). The glucagon receptor (GCGR) is a G protein-coupled receptor. GC is predominantly found in the liver. GC exerts its action both at the GCGR and the glucagon-like peptide receptor (GLP1R). Knockout studies as well as human mutation analysis have indicated therapeutic potential as well as concerns of modulation of the GCGR as a potential target for diabetes therapies. Three approaches to GCGR antagonism—small molecules, monoclonal antibodies, and antisense oligonucleotides—have demonstrated an impressive reduction in HbA1C in preclinical and clinical studies. However, adverse events such as an increase in weight cholesterol liver enzymes and alpha cell hyperplasia have stalled further clinical development. On the other hand, balancing the hyperglycemic effect of glucagon and retaining their beneficial effects, especially with weight loss and decrease in weight loss and hepatic steatosis by use of unimolecular coagonists with GLP1 and GIP have shown considerable promise in clinical trials.
Analysis of Factors Influencing Successful Implementation of ODA Projects for Rural Development: The Case of Kyrgyzstan
Authors: Choi Young-Chool , Song Yanghoon , Kong Ki Seo , Lee Ahyoun
Published: November 2023

This paper aims to identify factors that influence the successful implementation of ODA rural development projects for developing countries. To this end, it has analysed the implementation process of a project, ‘The Integrated Rural Development Project in Kyrgyz Republic’, currently being carried out in Kyrgyzstan via Good Neighbors International (GNI) with support from KOICA (Korean International Cooperation Agency). The analysis method employed in this study is decision tree analysis. By means of a review of previous studies on the implementation of ODA projects, variables that are believed to have an impact on the successful implementation of ODA rural development projects were derived. The values of each variable for thirty villages in Kyrgyzstan were derived and used as independent variables, and decision tree analysis was performed using the overall execution performance score for each village as the dependent variable. As a result, it was found that co-operation between field managers active at the project site and village residents was the most important determining factor of success.
The locus of curves with an odd subcanonical point
Authors: Contiero André , Fontes Aislan
Published: November 2023

We present an explicit construction of a compactification of the locus of smooth curves
whose symmetric Weierstrass semigroup at a marked point is odd. This construction extends Stöhr’s
techniques, which can be seen as a variant of Hauser’s algorithm for computing versal deformation
spaces. As an application, we prove the rationality of the locus for genus at most six.
Nowhere scattered $C^*$-algebras
Authors: Thiel Hannes , Vilalta Eduard
Published: November 2023

We say that a

C^*

-algebra is nowhere scattered if none of its quotients contains a minimal open projection. We characterize this property in various ways, by topological properties of the spectrum, by divisibility properties in the Cuntz semigroup, by the existence of Haar unitaries for states, and by the absence of nonzero ideal-quotients that are elementary, scattered or type

\mathrm{I}

. Under the additional assumption of real rank zero or stable rank one, we show that nowhere scatteredness implies even stronger divisibility properties of the Cuntz semigroup.
Classification of weighted dual graphs consisting of $-2$-curves and exactly one $-3$-curve
Authors: Yau Stephen S.-T. , Zhu Qiwei , Zuo Huaiqing
Published: November 2023

Let $(V, p)$ be a normal surface singularity. Let $\pi\colon (M, A)\to (V, p)$ be a minimal good resolution of $V$. The weighted dual graphs $\Gamma$ associated with $A$ completely describes the topology and differentiable structure of the embedding of $A$ in $M$. In this paper, we classify all the weighted dual graphs of $A=\bigcup_{i=1}^n A_i$ such that one of the curves $A_i$ is a $-3$-curve, and all the remaining ones are $-2$-curves. This is a natural generalization of Artin's classification of rational triple points. Moreover, we compute the fundamental cycles of maximal graphs (see § 5) which can be used to determine whether the singularities are rational, minimally elliptic or weakly elliptic. We also give formulas for computing arithmetic and geometric genera of star-shaped graphs.
Topological phases in the theory of solid states
Authors: Sergeev Armen Glebovich , Teplyakov Egor
Published: November 2023

The paper is a survey devoted to the topological phases -
one of the actively developing directions in the theory of solid states.
An interpretation of topological phases in terms
of the generalized cohomology theories and $K$-theory is given.
The renormalization group transformation in the generalized fermionic hierarchical model
Authors: Missarov Mukadas Dmukhtasibovich , Khajrullin Dmitrii Airatovich
Published: November 2023

We consider a two-dimensional hierarchical lattice in which the vertices
of a square represent an elementary cell. In the generalized hierarchical model,
the distance between opposite vertices of a square differs from that
between adjacent vertices and is a parameter of the new model.
The Gaussian part of the Hamiltonian
of the 4-component generalized fermionic hierarchical model
is invariant
under the block-spin renormalization group transformation.
The transformation of the renormalization group in the space of coefficients,
which specify the Grassmann-valued density of the free measure, is explicitly
calculated as a homogeneous mapping of degree four in the two-dimensional
projective space.
On optimization of coherent and incoherent controls for two-level quantum systems
Authors: Morzhin Oleg Vasilevich , Pechen Alexander Nikolaevich
Published: November 2023

This paper considers some control problems for closed and open two-level quantum systems.
The closed system's dynamics is governed by the Schrödinger
equation with coherent control. The open system dynamics is governed by the Gorini-Kossakowski-Sudarshan-Lindblad master equation whose Hamiltonian depends on coherent control and superoperator of dissipation depends on incoherent control. For the closed system, we consider the problem of generation of the phase shift gate for some values of phases and final times for which we numerically show that zero coherent control, which is a stationary point of the objective functional, is not optimal; it gives an example of subtle point for practical solving quantum control problems. The two-stage method, which was developed in [48]
for generic $N$-level open quantum systems for approximate generation of a given target density matrix, is modified here for the case of two-level systems. We modify the first ("incoherent") stage by numerically optimizing piecewise constant incoherent control instead of using constant incoherent control analytically computed using eigenvalues of the target density matrix. Exact analytical formulas are derived for the system state evolution, the objective functions and their gradients for the modified first stage. These formulas are then applied in the two-step gradient projection method. The numerical simulations show that the modified first stage
duration can be significantly less than the unmodified first stage duration, but at the cost of performing optimization in the class of piecewise constant controls.
On weak solutions of boundary value problems for some general differential equations
Authors: Burskii Vladimir Petrovich
Published: November 2023

We study general settings of the Dirichlet problem, the Neumann problem, and other boundary value problems for equations and
systems of the form $\mathcal{L}^+ A\mathcal{L}u=f$ with general (matrix, generally speaking)
differential operation $\mathcal{L}$ and some linear or non-linear operator $A$ acting in $L^k_2(\Omega)$-spaces.
For these boundary value problems, results on well-posedness, existence and uniqueness of a weak solution are obtained.
As an operator $A$, we consider Nemytskii and integral operators.
The case of operators involving lower-order derivatives is also studied.
Two-weight estimates for Hardy-Littlewood maximal functions and Hausdorff operators on $p$-adic Herz spaces
Authors: Dung Kieu Huu , Duong Dao Van
Published: November 2023

This paper is concerned with some sufficient conditions for the boundedness of Hardy-Littlewood maximal functions, rough Hausdorff and matrix Hausdorff operators on two-weighted Herz spaces on $p$-adic fields through its atomic decomposition.
Reduced risk of dementia in patients with type 2 diabetes mellitus using Chinese herbal medicine: A nested case-control study
Authors: Liao Hou-Hsun , Livneh Hanoch , Huang Hua-Lung , Hung Jui-Yu , Lu Ming-Chi , Guo How-Ran , Tsai Tzung-Yi
Published: November 2023

The complication of diabetes, which is known as diabetic foot ulcer (DFU), is a significant concern due to its association with high rates of disability and mortality. It not only severely affects patients’ quality of life, but also imposes a substantial burden on the healthcare system. In spite of efforts made in clinical practice, treating DFU remains a challenging task. While mesenchymal stem cell (MSC) therapy has been extensively studied in treating DFU, the current efficacy of DFU healing using this method is still inadequate. However, in recent years, several MSCs-based drug delivery systems have emerged, which have shown to increase the efficacy of MSC therapy, especially in treating DFU. This review summarized the application of diverse MSCs-based drug delivery systems in treating DFU and suggested potential prospects for the future research.
Exploring the targets and molecular mechanism of glycyrrhetinic acid against diabetic nephropathy based on network pharmacology and molecular docking
Authors: Meng Fan-Di , Yuan Ling , Xu Duo-Jie , Che Meng-Ying , Hou Shao-Zhang , Lu Dou-Dou , Liu Wen-Jing , Nan Yi
Published: November 2023

The complication of diabetes, which is known as diabetic foot ulcer (DFU), is a significant concern due to its association with high rates of disability and mortality. It not only severely affects patients’ quality of life, but also imposes a substantial burden on the healthcare system. In spite of efforts made in clinical practice, treating DFU remains a challenging task. While mesenchymal stem cell (MSC) therapy has been extensively studied in treating DFU, the current efficacy of DFU healing using this method is still inadequate. However, in recent years, several MSCs-based drug delivery systems have emerged, which have shown to increase the efficacy of MSC therapy, especially in treating DFU. This review summarized the application of diverse MSCs-based drug delivery systems in treating DFU and suggested potential prospects for the future research.
Archaeology, rapid climate changes in the Holocene, and adaptive strategies
Authors: Budja Mihael
Published: November 2023

The article presents the concepts of repeating cycles of rapid climate variability in the Holocene, including rapid cooling cycles, cold events, ice-rafting events, and rapid climate change recorded in palaeoclimate archives. It also discusses the concepts of adaptation strategies embedded in the catastrophic scenarios of collapse on the one hand, and panarchy, resilience, and adaptation cycle on the other, i.e. the processes of transforming social hierarchical structures into dynamic, adaptive entities. In the rapid climate change series we focus on the 9.2 ka and 8.2 ka climate events associated with the Neolithisation process and the transition to farming. The 5.9 IRD event and/or period of rapid climate change from 6000–5200 cal yr BP are associated with the cultural, economic, and demographic collapse of the Early Neolithic Linear Pottery culture in central and western Europe. We also discuss the triad of recent weakening of North Atlantic ocean circulation, decreased solar activity, and the hypothesised transition to a cold period, the well-known historical scenario associated with the transition to Little Ice Age between 1450 and 1850.
Złodziejki pochodzące z Wielkopolski wschodniej osadzone w domu karnym w fordonie w okresie międzywojennym
Authors: Juszczak Magdalena
Published: November 2023

W artykule zostały przedstawione wyniki analizy akt złodziejek pochodzących z Wielkopolski Wschodniej osadzonych w Domu Karnym w Fordonie w okresie międzywojennym. Został przedstawiony portret socjodemograficzny osadzonych, akty oskarżenia, opis poszczególnych przestępstw i wymiar kary oraz przedterminowe zwolnienie na mocy ustawy amnestyjnej.

Thieves From Eastern Greater Poland Set in the Penalty House in Fordon in the Inter-War Period: The article presents the results of the analysis of files of thieves from Eastern Greater Poland imprisoned in the Penitentiary House in Fordon in the interwar period. A sociodemographic portrait of inmates, indictments, description of individual crimes and sentences as well as early release under the amnesty law were presented.
Unpacking Continuous Assessment: Teacher Knowledge and Attitudes in Zimbabwe Rural Secondary Schools
Authors: Makuvire Claretah , Mufanechiya Albert , Dube Bekithemba
Published: November 2023

The paper explores the implementation of continuous assessment in the context of teacher knowledge and attitudes in Zimbabwean rural secondary schools. Continuous assessment is a new curriculum assessment regime in the curriculum reform agenda in Zimbabwe introduced in the 2015 updated curriculum.The study defines continuous assessment as the mechanism where thelearner performs over timeconstitutes the final gradingof the learner.The researchers explain the teacher-related implementation challenges in continuous assessment in rural secondary schools in Zimbabwe. Ten teachers and five secondary school heads from Goromonzi District of Mashonaland East Province in Zimbabwe participated in the study. The five participating heads were conveniently selected, while theten teachers were randomly sampled to participate in the case study.Semi-structured questionnaires and in-depth interviews were used to collect qualitative data on rural teachers’ conceptualisationof continuous assessment and how this had shaped their attitudes towardthe concept. The general finding from the study was that the new assessment regime had empowered the teachers to make critical decisions about the students they teach and allow learners to co-create knowledge relevant to their life contexts.However, their concerns were around the absence of knowledgeable professionals in the area who can cascade and message the correct and accurate information regarding the implementation of the assessment reform.The study further found that this weakness in the implementation chain had resulted in negative attitudes of teachers and school heads. The study recommends that the Ministry of Primary and Secondary Education revisit the current continuous assessment to takeon board all educational stakeholders’ concerns for effective implementation of the assessment reform.
CONTRIBUTION TO THE STUDY OF THE SCENE OF BAPTISM OF CHRIST IN SERBIAN MEDIEVAL ART WITH SPECIAL INTEREST IN THE CHURCH OF SAINT NIKITA NEAR SKOPLJE (AROUND 1324; 1484)
Authors:   University of Belgrade, Faculty of Philosophy, Gavrilović Anđela
Published: November 2023

The subject of this paper is the motif of the stone slab (cheirograph) in the scene of Baptism in Serbian medieval monumental painting and on icons on which Christ stands and under which he suppresses serpent-like monsters: its iconography, literary sources and meaning (ill. 5). The article represents the first study of the issue of cheirograph in Baptism scenes in Serbian medieval art from its beginning until the end of the art done in the Byzantine tradition (1800). It provides the survey of the chosen examples of this motif and explains the nuances in the meaning of both the Baptism scene itself and its relation to the painted decorations of each monument (ill. 1–4, 6–9). Special attention is given to the motif of the stone slab in the church of Saint Nikita in Skoplje, the foundation of king Milutin (built: 1299/1300 –1308; decorated with frescoes: around 1324; 1484; 1846).
Use Of Standard Clauses in Transactions Therapeutics Based on Regulation Theory
Authors: Carwan Carwan , Lestari Sari Indah
Published: November 2023

The standard informed consent clause is prepared and formed by one of the parties to make it easier for doctors and patients to create a therapeutic agreement. One of the parties designed and developed this standard clause to make it easier for doctors and patients to form a therapeutic contract. However, in practice, it is found that the application of standard clauses prepared in advance by hospitals or doctors is only concerned with signatures and has an impact of dissatisfaction that is detrimental to patients. The research method used is juridical-normative. The results showed that based on the theory of legislation, normatively, the standard clause does not violate the principle of freedom of contract because the standard informed consent clause in the Therapeutic Transaction is a form of the initiative of doctors and hospitals as parties who have more expertise to form the main guidelines for doctors and patients in carrying out health services. In Decision Number 63/Pdt.G/2021/PN Kpn, the use of standardized informed consent clauses in therapeutic agreements provides repressive legal protection in the trial and has a positive influence, namely strengthening informed consent as vital and valid evidence in the problem because it has guided whether medical actions are carried out by the agreed actions, SP, SOP, and patient needs.
State of Climate Action 2023
Authors: Boehm Sophie , Jeffery Louise , Hecke Judit , Schumer Clea , Jaeger Joel , Fyson Claire , Levin Kelly , Nilsson Anna , Naimoli Stephen , Daly Emily , Thwaites Joe , Lebling Katie , Waite Richard , Collis Jason , Sims Michelle , Singh Neelam , Grier Emma , Lamb William , Castellanos Sebastian , Lee Anderson , Geffray Marie-Charlotte , Santo Raychel , Balehegn Mulubrhan , Petroni Michael , Masterson Maeve
Published: November 2023

The State of Climate Action 2023 provides the world’s most comprehensive roadmap of how to close the gap in climate action across sectors to limit global warming to 1.5°C. It finds that recent progress toward 1.5°C-aligned targets isn’t happening at the pace and scale necessary and highlights where action must urgently accelerate this decade to reduce greenhouse gas emissions, scale up carbon removal and increase climate finance.
Pendidikan Nilai Karakter Religiositas Anak Usia Dini
Authors: Aumar Suyanee , Jatmikowati Tri Endang , Rachman Angraeny Unedia
Published: November 2023

This study is an educational analysis aimed at shaping the attitudes and behavior of children to become good and morally upright individuals. The purpose of this research is to understand the implementation of religious character values for early childhood in PAUD Yasmin, Jember Regency. The research is of a qualitative descriptive type and employs data collection techniques such as observation, interviews, and documentation. The research findings regarding the implementation of religious character values for young children by teachers in the learning activities include the use of visual media, videos, and storytelling. In the application of religious character values for the early childhood group, this is achieved through daily routines such as Dhuha prayers, reciting prayers, memorizing short verses, and Quranic recitation. For the Playgroup age group, the application of religious character values is also carried out through daily routines, including Dhuha prayers, memorizing short verses, and reciting prayers. In the case of the Islamic Education Group (TPA), this is done through daily routines involving reciting prayers, memorizing short verses, and singing Islamic children's songs. In conclusion, the implementation of religious character values for young children can be integrated into the learning activities and further developed through self-improvement and character building for young children in their daily lives.
Kesulitan yang Dihadapi Anak Usia Dini dalam Memahami Teks dan Strategi Mengatasinya
Authors: Arifin Shafira Farha , Wardhani Wahju Dyah Laksmi , Kusumaningtyas Nuraini
Published: November 2023

The ability to read is one of the most crucial skills in everyday life. Through reading, a person can acquire knowledge, information, and develop an understanding of the world around them. Good reading skills also form a vital foundation in the learning process at school. This research aims to identify and analyze effective methods for improving early childhood reading abilities, as well as to explore potential challenges faced by young children in understanding text and the factors influencing their reading development. This study is a qualitative case study. The research reveals a significant positive influence of these methods on letter and word recognition, as well as reading comprehension. Therefore, educators and parents can utilize these methods to support and enhance reading abilities, as strong reading skills have long-term benefits for a child's academic development.
Digitalisasi Sistem Informasi Partai Politik ( Sipol ) pada Tahapan Verifikasi Pencalonan Partai Politik untuk Pemilu Tahun 2024 di Komisi Pemilihan Umum ( KPU ) Kabupaten Jember
Authors: Astutik Hesti Dwi , Angin Ria
Published: November 2023

Salah satu tugas KPU adalah melakukan verifikasi administrasi, verifikasi faktual dan menetapkan partai politik sebagai peserta pemilu. Pelaksanaan tugas tersebut dilakukan melalui  pemanfaatan Sistem Informasi Partai politik (Sipol) yang merupakan salah satu inovasi untuk meningkatkan kinerja KPU sehingga bisa lebih efektif. Berkaitan dengan hal tersebut tujuan penelitian ini adalah untuk memberikan gambaran tentang digitalisasi sistem informasi partai politik pada tahapan verifikasi pencalonan partai politik sebagai peserta pemilu tahun 2024 di KPU Kabupaten Jember. Penelitian ini menggunakan metode deskriptif kualitatif dengan pengumpulan data secara observasi, wawancara dan dokumentasi. Hasil Penelitian menunjukkan bahwa: pertama, kualitas sistem  belum baik yang ditandai dengan masih belum adanya jaminan data bisa masuk secara serentak dalam waktu yang bersamaan. Kedua, kualitas informasi yang diberikan oleh KPU Kabupaten terhadap partai politik cukup baik,  akan tetapi pada saat pengumpulan data informasi yang diterima oleh KPU Kabupaten Jember dari partai politik baru kurang akurat. Ketiga, kualitas pelayanan  KPU Kabupaten Jember terhadap proses pencalonan partai politik cukup baik  mulai dari awal pendaftaran, verifikasi hingga penetapan partai politik yang bisa lolos pada pemilihan umum tahun 2024.
Programa Segundo Tempo Universitário no atendimento ao esporte educacional em uma Instituição de Ensino Superior na região Centro-Oeste em Brasil
Authors: Vinícius Almeida Vargas Nathan , Marta Antunes Ramos Juliana , Brey D'auria Breno , Sumára Gomes dos Santos Roman Andreza , Bonjiovanne Lourenço Otávio , Silva Dirceu Santos
Published: November 2023

A prática esportiva apresenta inúmeras manifestações, que ao longo dos anos sofreram modificações. No contexto universitário, com a premissa de assegurar como direito constitucional, em 2009, o Governo Federal, criou a vertente do Programa Segundo Tempo (PST) Universitário, que visa possibilitar ao corpo discente o acesso à prática do esporte educacional. Dessa forma, o presente estudo tem como objetivo analisar o planejamento, a formação e avaliação do PST Universitário na Universidade Federal do Mato Grosso do Sul (UFMS). Para tanto, utilizou-se da pesquisa descritiva com abordagem qualitativa, com coleta de dados por meio de entrevistas semiestruturadas realizadas com os professores e monitores. Os dados foram analisados conforme proposta de Bardin (2009). O planejamento e estruturação do PST Universitário foram realizados pelo coordenador, de acordo com as diretrizes do programa, que não prevê a participação do professor e dos monitores. De acordo com relato dos entrevistados, a formação não foi realizada conforme diretrizes, mas as reuniões de planejamento se mostraram significativas para a formação profissional. O principal impacto do programa avaliado foi na oferta de prática esportiva como direito. Dessa forma, conclui-se que o PST Universitário contribui para o acesso ao esporte educacional do corpo discente, bem como para a formação profissional, conforme previsto nas diretrizes. Contudo, faz-se necessário a participação dos professores na construção do planejamento, haja vista que na implementação existe uma dissociação entre quem planeja e executa.
Palavras-chave: Política Social; Política Educacional; Política Pública; Esportes; Avaliação.
Forming the professional culture of a future specialist in the field of adaptive physical education and sport
Authors: Kopzhanov Galymzhan , Doshybekov Aidyn , Belegova Aliya , Orlov Alexander , Duisembek Abylay
Published: November 2023

The study of the issue of features of the organisation of adaptive physical education and sport is becoming increasingly popular in social and pedagogical research. In particular, since all over the world and respectively in the Republic of Kazakhstan more and more attention is paid to the expansion of opportunities for people with disabilities. That is why at the moment it is necessary to actively study the processes connected with training and formation of professional competence of specialists of this category. Hence, the purpose of the article is to analyse the available means and approaches to the educational and professional training of future employees in the sphere of adaptive physical culture and sports. Different methodological means were used for this study, among which, functional and dialectical approaches and the method of analysis and synthesis, comparison, classification, and generalisation. The results of the work done are theoretical and practical conclusions that relate to the issue under study and reveal its essence. In particular, at the beginning of the article the basic terms, in particular, adaptive physical education and professional competence of a specialist in adaptive sports were studied to fully characterise the object of research. In turn, the final component reveals specific approaches and ways of implementing training and imparting professional knowledge to future specialists. The practical value of this study is revealed in the fact that it can be used for different purposes – both in the form of methodological materials for academic disciplines and courses preparing specialists in this category and as additional material for persons wishing to improve their professional qualification. Future research papers should identify the specificities of teacher training in adaptive physical education and sport.
Keywords: Education, special pedagogy, correction, rehabilitation, people with disabilities, adaptive physical education, adaptive sport
Article RETRACTED due to manipulation by the authors
Authors: Pratama Kukuh Wahyudin , Suharjana Suharjana , Nasrulloh Ahmad , Sabrin La Ode Maklum , Pranata Doni , Pambayu Septadi Hanif , Hardianto Deni , Sutapa Panggung , Auliana Rizqie , Karakauki Manil , Utami Danarstuti , Riyana Ardi , Astuti Ari Tri , Utami Desy Yunita , Trisnadi Reza Adityas , Amran Amran , Ali Syed Kamaruzaman Syed , Mustapha Aida , Razali Muhammad Nazim , Sonjaya Azhar Ramadhana , Permadi Asep Angga , Arifin Z.
Published: November 2023

RED-S is a contraindication for women in the sport. The purpose of the exercise was originally getting results in the form of a healthy and a fit body, but the female athletes when exercise is done with intensity is too high then suffered great mental distress that would arise RED-S disease include anorexia nervosa, amenorrhea, and osteoporosis. This study aims to identify the RED-S in women swimmer athletes. The results showed that the identification of RED-S in the women swimmer athlete is as follows: In objective based on the control of anorexia nervosa in detail that there were 26 (100%) athletes who entered in categories of anorexia nervosa. While the detailed control of amenorrhoea that there are 25 (96.15%) athletes who fall into the category of secondary amenorrhoea and 1 (3.85%) athletes who fall into the category of primary amenorrhoea. Then in the control of Osteoporosis in detail there are 0 (0%) athletes who fall into the category of high osteoporosis, 12 (46.15%) athletes who fall into the category of moderate osteoporosis, and 14 (53.85%) athletes who fall into the category of low osteoporosis. In Subjective based on the tendency of the RED-S, as many as three athletes (11.54 %) were in the category of very high, 3 athletes (11.54 %) were in the high category, 13 athletes (50.00%) were in the category of being, 5 athletes (19.23 %) were categorized as low, and 1 athlete (3.85%) were categorized as very low. While based on the RED-S risk factors, as many as four athletes (15.38%) were in the category of very high, 5 athletes (19.23%) were in the high category, 12 athletes (46.15%) were in the category medium, 2 athletes (7.69 %) were included in the low category, and 3 athletes (11.54%) were in the category of very low.
Keywords: RED-S, Female Athlete, Swimmer.
A influência do índice de desenvolvimento humano municipal sobre o desenvolvimento de políticas esportivas educacionais, de rendimento ou de lazer no Brasil
Authors: Micaliski Emerson Liomar , Radtke Junior Claúdio Helio , Hertes Andrelise , Ordonhes Mayara Torres , Figuerôa Katiuscia Mello , Cavichiolli Fernando Renato
Published: November 2023

Este estudo teve por objetivo descrever as características da gestão esportiva municipal e verificar se o índice de desenvolvimento humano municipal exerce influência sobre o desenvolvimento de políticas esportivas educacionais, de rendimento ou de lazer. O estudo possui abordagem quantitativa e consiste em um estudo ex post facto. A pesquisa foi desenvolvida por meio do levantamento de dados da Pesquisa de Informações Básicas Municipais de 2016 e do Censo Demográfico de 2010, sistematizados pelo Instituto Brasileiro de Geografia e Estatística. Com a realização da pesquisa, evidenciou-se que existe uma diferença entre a escolaridade dos homens e das mulheres para ocupar o cargo de gestor e, de modo geral, verificou-se a importância de os gestores possuírem conhecimento técnico para executar suas tarefas. Além disso, pode-se perceber que existe uma tendência maior na realização de ações esportivas de rendimento quando os municípios possuem Índice de Desenvolvimento Humano Municipal maior.
Palavras-chave: Esportes, Política pública, Gestão esportiva.
The Relative Age Effect of Participants in the World Junior Tennis Finals in 2012–2016
Authors: Agricola Adrian , Polách Michal , Válek Tomáš , Nykodým Jiří , Zháněl Jiří
Published: November 2023

The main aim was to verify the Relative Age Effect (RAE) between female junior tennis players (U14, n=240), participants of the World Junior Tennis Finals in 2012–2016. The secondary aim was to verify the RAE on the order of nomination to each national team and then verify the RAE on the final ranking of the teams. The third aim was to compare the RAE between junior female tennis players and the world's best senior female players. Chi-square test and Effect Size (ES) index w were used for statistical data analysis. Statistically significant RAE was found in each of the years 2012–2016 for all subgroups, ES ranged between medium and large. Statistically significant RAE was found for all female players over the entire five-year period, ES was medium. Statistically significant RAE was found in all cases for nominations of players (the first, second and third tennis player of team), ES ranged between medium and large. In all four performance groups (1st-4th, 5th-8th, 9th-12th, 13th-16th), the RAE was statistically significant, ES was medium and large. Comparison of RAE between the groups of junior tennis players and the world's best players showed non-significant differences, the ES was small.
Keywords: Date of birth. Chronological age. Age distribution. Youth sports. Sports.
The Effects of Trademark Registration for MSMEs
Authors: Balik Agustina , Tjoanda Merry , Sopamena Ronald Fadly
Published: November 2023

Introduction: Trademark rights are exclusive rights granted by the state to trademark owners who are registered for a certain period by using the brand themselves or by giving permission to other parties to use it. Based on Article 3 of Act No. 20 of 2016 Regarding Trademarks and Geographical Indications, it states that trademark rights are obtained after the Brand is registered. Thus, registration is a requirement to obtain legal protection in the field of Trademarks in the field of IPR. The presence of MSMEs in improving the national trade must be supported by the application of laws that function to protect and provide investment guarantees as wide as possible. Purposes of the Research:  In the Maluku province, based on data owned by the Maluku Province Cooperatives and MSME Office, many MSMEs have used brands on their business products, but only a few have registered their brands. Factors that influence MSMEs not to register their trademarks are the lack of knowledge and information about the importance of trademark registration. Even though seen from the prospects for MSME businesses in the Maluku province, it is very promising to be able to compete in national and international trade markets.Methods of the Research: The research method used in this study is normative juridical with the nature of the research, namely analytical descriptive. The problem approach used is a statutory and conceptual approach. The analysis of legal materials used is a literature analysis supported by additional data obtained in the field.Results of the Research: Efforts to create IPR-based development strategies is a new challenge for the government to make as a reality. The government's role is very important in spurring and activating MSMEs business actors in managing and implementing marketing strategies that can increase selling power and healthy competitiveness. Registration of trademarks in order to obtain intellectual property rights protection must be a top priority in creating intellectual property-based development. Counseling and outreach regarding the importance of legal registration of marks must be carried out from now on. Not only that, but the process of assisting MSMEs in the registration process must also be carried out, so that the counseling and legal outreach that has been carried out produces results. The advantage that can be obtained by MSMEs if their trademark is registered is the legal protection provided by the state to them, so that there will be no open gaps for other business actors to take advantage of said trademarks.
Upaya ASEAN Terhadap Eksploitasi Anak Untuk Perdagangan Narkotika
Authors: Sopamena Siska Vilonia Indah , Talaperuw Vivi , Pattipeilohy Quentyn Priscilla
Published: November 2023

Introduction: It is important to study child exploitation in the drug trade, its causes, and develop effective strategies to prevent and address this problem. ASEAN plays an important role for Southeast Asian countries fighting drug trafficking.Purposes of the Research: The purpose of this article is to study ASEAN's efforts in tackling the exploitation of children in the drug tradeMethods of the Research: Research for this article uses a normative juridical method, namely a method that examines and analyzes the substance of laws and regulations related to the subject matter of legal problems.Results of the Research: ASEAN's efforts in tackling the exploitation of children in drug trafficking are by prioritizing three essential things, namely policies, approaches and strategies, making sure that the views, approaches and coping methods used are aligned with the vision and mission of the ASEAN organization itself and can be approved by all members belonging to ASEAN. ASEAN’s efforts to this problematic phenomenon is by developing related legal products, cooperating with the Customs among countries, provide counseling on narcotics as a preventive measure, and more training to increase participation in these issues regionally.
Peran Masyarakat Adat Dalam Menjaga Dan Melestarikan Lingkungan Hidup
Authors: Noya Ekberth Vallen
Published: November 2023

Introduction: This article outlines an analysis of the role of indigenous communities in protecting and preserving the environment through the traditional Kewang institution, so that the implementation of Sasi can run well.Purposes of the Research: The purpose of this article is to look at the role of indigenous communities in protecting and preserving the environment based on applicable customary law.Methods of the Research: The method used in this research is normative juridical which focuses on the main law by examining theories, concepts, legal principles and statutory regulations related to this research.Results of the Research: Environmental awareness is awareness that arises from an understanding of the relationship between humans and their environment. Awareness that humans are an integral part that cannot be separated from their environment is the key to successful environmental management. Through this understanding, on the one hand, it is hoped that good and healthy environmental quality will be realized as one of the constitutional rights of citizens as regulated in Article 28H of the 1945 Constitution. Community participation as an effort to protect the law can be seen in the applicable regulations. Indigenous communities in their role of protecting the environment, the Kewang institution has a big role, through Sasi, the kewang can carry out the function of protecting and preserving the environment.
Long-Term Psychosocial Issues among COVID-19 Survivors in Kathmandu Valley
Authors:   Counseling Psychologist, Faculty at Master Program in Counseling Psychology, Tribhuvan University and Founder CEO, PICS Nepal, Prasad Joshi Nabin
Published: November 2023

Since its emergence in December 2019, Corona Virus disease has impacted several countries, affecting many people. The first cases were recorded in Wuhan, China, between December 2019 and January 2020. Italy is one of the affected countries in Europe. The relations between India and Nepal have reverted to the pre-pandemic period as both countries have open borders. The study focused on the overall psychosocial impact among covid-19 survivors in their life what are the changes they are facing after covid also how are their relations with friends and relatives after they have covid in different municipalities of Kathmandu Valley, where people from different regions are living in rent and have their own houses. Support from friends and family during a pandemic can prevent it if it is strong enough. Nonetheless, there were risk factors for psychosocial damage, including a lack of or insufficient family and social support, psychiatric assistance, and inadequate insurance or compensation. Poorer mental health outcomes were inversely correlated with social rejection or isolation