bluuebunny/crossref_metadata_2025 huggingface dataset:
‘Same, but different’: A mixed-methods realist evaluation of a cluster-randomized controlled participatory organizational intervention
Authors: Abildgaard Johan Simonsen , Nielsen Karina , Wåhlin-Jacobsen Christian Dyrlund , Maltesen Thomas , Christensen Karl Bang , Holtermann Andreas
Published: October 2019

Participatory organizational interventions are a recommended approach to improve the psychosocial work environment. As interventions of this type are shaped by employees and managers, their implementation can vary considerably, making evaluation challenging. This study contributes to our understanding of interventions by focusing on how the intervention mechanisms and the organizational context interact. In a mixed-methods design, we use multi-group structural equation modelling of pre-and post-intervention survey data ( N = 204) to test multiple mediational mechanisms in three different contexts. We then analyse interviews ( N = 67) and field observations of workshops to identify the role of contextual factors. The findings suggest that participatory organizational interventions do not produce one-size-fits-all results; on the contrary, intervention results are better understood as products of multiple intervention mechanisms interacting with the specific organizational contexts.
Subgingival Microbiota and Longitudinal Glucose Change: The Oral Infections, Glucose Intolerance and Insulin Resistance Study (ORIGINS)
Authors: Demmer R.T. , Trinh P. , Rosenbaum M. , Li G. , LeDuc C. , Leibel R. , González A. , Knight R. , Paster B. , Colombo P.C. , Desvarieux M. , Papapanou P.N. , Jacobs D.R.
Published: October 2019

Microbial communities along mucosal surfaces throughout the digestive tract are hypothesized as risk factors for impaired glucose regulation and the development of clinical cardiometabolic disease. We investigated whether baseline measures of subgingival microbiota predicted fasting plasma glucose (FPG) longitudinally. The Oral Infections, Glucose Intolerance and Insulin Resistance Study (ORIGINS) enrolled 230 diabetes-free adults (77% female) aged 20 to 55 y (mean ± SD, 34 ± 10 y) from whom baseline subgingival plaque and longitudinal FPG were measured. DNA was extracted from subgingival plaque, and V3 to V4 regions of the 16S rRNA gene were sequenced. FPG was measured at baseline and again at 2 y; glucose change was defined as follow-up minus baseline. Multivariable linear models regressed 2-y glucose change onto baseline measures of community diversity and abundances of 369 individual taxa. A microbial dysbiosis index (MDI) summarizing top individual taxa associated with glucose change was calculated and used in regression models. Models were adjusted for age, sex, race/ethnicity, education, smoking status, body mass index, and baseline glucose levels. Statistical significance was based on the false discovery rate (FDR; <0.05) or a Bonferroni-corrected P value of 1 × 10-4, derived from the initial 369 hypothesis tests for specific taxa. Mean 2-y FPG change was 1.5 ± 8 mg/dL. Baseline levels of 9 taxa predicted FPG change (all FDR <0.05), among which Stomatobaculum sp oral taxon 097 and Atopobium spp predicted greater FPG change, while Leptotrichia sp oral taxon 498 predicted lesser FPG change (all 3 P values, Bonferroni significant). The MDI explained 6% of variation in longitudinal glucose change ( P < 0.001), and baseline glucose levels explained 10% of variation ( P < 0.0001). FPG change values ± SE in the third versus first tertile of the MDI were 4.5 ± 0.9 versus 1.6 ± 0.9 ( P < 1 × 10-4). Subgingival microbiota predict 2-y glucose change among diabetes-free men and women.
Mesenchymal Progenitor Regulation of Tooth Eruption: A View from PTHrP
Authors: Nagata M. , Ono N. , Ono W.
Published: October 2019

Tooth eruption is a unique biological process by which highly mineralized tissues emerge into the outer world, and it occurs concomitantly with tooth root formation. These 2 processes have been considered independent phenomena; however, recent studies support the theory that they are indeed intertwined. Dental mesenchymal progenitor cells in the dental follicle lie at the heart of the coupling of these 2 processes, providing a source for diverse mesenchymal cells that support formation of the highly functional tooth root and the periodontal attachment apparatus, while facilitating formation of osteoclasts. These cells are regulated by autocrine signaling by parathyroid hormone–related protein (PTHrP) and its parathyroid hormone/PTHrP receptor PPR. This PTHrP-PPR signaling appears to crosstalk with other signaling pathways and regulates proper cell fates of mesenchymal progenitor cell populations. Disruption of this autocrine PTHrP-PPR signaling in these cells leads to defective formation of the periodontal attachment apparatus, tooth root malformation, and failure of tooth eruption in molars, which essentially recapitulate primary failure of eruption in humans, a rare genetic disorder exclusively affecting tooth eruption. Diversity and distinct functionality of these mesenchymal progenitor cell populations that regulate tooth eruption and tooth root formation are beginning to be unraveled.
Linking Variation in Perception and Production in Sound Change: Evidence from Dutch Obstruent Devoicing
Authors: Pinget Anne-France , Kager René , Van de Velde Hans
Published: October 2019

This study investigates the link between the perception and production in sound change in progress, both at the regional and the individual level. Two devoicing processes showing regional variation in Dutch are studied: the devoicing of initial labiodental fricatives and of initial bilabial stops. Five regions were selected, to represent different stages of change in progress. For each region, 20 participants took part in production (Study 1) and perception (Study 2) experiments. First, the results of the production tasks give additional insight in the regional and individual patterns of sound change. Second, the regional perceptual patterns in fricatives match the differences in production: perception is the most categorical in regions where the devoicing process is starting, and the least categorical in regions where the process of devoicing is almost completed. Finally, a clear link is observed between the production and perception systems undergoing sound change at the individual level. Changes in the perceptual system seem to precede changes in production. However, at the sound change completion, perception lags behind: individuals still perceive a contrast they no longer produce.
Gratitude and Suicidal Ideation in Undergraduates in Taiwan: The Mediating Role of Self-Esteem and Meaning in Life
Authors: Lin Chih-Che
Published: October 2019

This study examined both the mediation effects of self-esteem and meaning in life for the relationship between gratitude and suicidal ideation in late adolescence. A total of 276 Taiwanese university students completed measures of gratitude, self-esteem, meaning in life, and suicidal ideation. Path analyses indicated that self-esteem and meaning in life acted as full mediators of the association between gratitude and suicidal ideation. The identified model also revealed a significant path from gratitude through self-esteem and meaning in life to suicidal ideation. A multigroup analysis found that the paths did not differ by genders. Implications for future research and limitations of the present findings are discussed.
Improved outcomes in neonates who require venoarterial extracorporeal membrane oxygenation after the Norwood procedure
Authors: De Jesus-Brugman Nicole , Hobson Michael Joe , Herrmann Jeremy L , Friedman Matthew L , Cordes Timothy , Mastropietro Christopher W
Published: October 2019

Background:

Extracorporeal membrane oxygenation after the Norwood procedure has historically been associated with poor outcomes, with reported hospital survival rates of 13%–48%. We hypothesized that contemporary outcomes in this population have improved. We aimed to compare clinical outcomes of contemporary cohorts of patients with functional single ventricle physiology who did and did not receive extracorporeal membrane oxygenation after the Norwood procedure.

Methods:

Single-center retrospective cohort study of patients with single ventricle anatomy who underwent the Norwood procedure between 2009 and 2017 was performed. Kaplan–Meier survival curves were constructed, and Cox proportional hazard regression analyses were performed to compare transplant-free survival in patients who did and did not receive venoarterial extracorporeal membrane oxygenation.

Results:

In total, 85 patients met inclusion criteria. Venoarterial extracorporeal membrane oxygenation was utilized in 25 patients (29%). A total of 18 patients (72%) who received venoarterial extracorporeal membrane oxygenation survived to hospital discharge, compared to 54 patients (92%) who did not receive venoarterial extracorporeal membrane oxygenation (p = 0.013). Post-discharge transplant-free survival was not significantly different between patients who did and did not receive venoarterial extracorporeal membrane oxygenation (log-rank p value = 0.28). Cox proportional hazard regression analysis revealed that the occurrence of cardiac arrest requiring cardiopulmonary resuscitation (hazard ratio = 4.5; 95% confidence interval = 2.0–10.1) during the perioperative period was independently associated with death or transplantation, whereas venoarterial extracorporeal membrane oxygenation was not an independent risk factor for death or transplantation (hazard ratio = 2.0; 95% confidence interval = 0.8–4.9).

Conclusion:

In our cohort of children who received venoarterial extracorporeal membrane oxygenation after the Norwood procedure, hospital survival was improved compared to historical data. In addition, venoarterial extracorporeal membrane oxygenation utilization was not independently associated with worse outcomes.
Environmental assessments of biological treatments of biowaste in life cycle perspective: A critical review
Authors: Vieira Victor Hugo Argentino de Morais , Matheus Dácio Roberto
Published: October 2019

Municipal biowaste is a major environmental issue. Life-cycle assessment is a valuable tool to assess recycling options, and anaerobic digestion and composting have performed adequately. However, reviews indicate several discrepancies between studies. Thus, we critically review 25 life-cycle assessments of the composting and anaerobic digestion of municipal biowaste. Our objective is to identify decisive factors, methodological gaps and processes that affect environmental performance. We generally identified methodological gaps in expanding systems borders. In energy systems, the replaced energy source did not consider power generation or dynamic regulation. All studies adopted mixed energy sources or marginal approaches. Agroecosystems included the carbon sequestration potential and compensation for the production of synthetic fertilizers only. A limited range of scientifically proven benefits of compost use has been reported. In general, studies provided a limited account of the effects of use on land emissions, but contradictory assumptions emerged, mainly in modelling synthetic fertilizer compensation. Only three studies compensated direct emissions from the use of synthetic fertilizers, and none included indirect emissions. Further studies should include an analysis of the additional benefits of compost use, compensate for the effects of emissions from synthetic fertilizer use on land and mix attributional and consequential approaches in energy system expansion.
Daily Protein Intake and Distribution of Daily Protein Consumed Decreases Odds for Functional Disability in Older Americans
Authors: McGrath Ryan , Stastny Sherri , Casperson Shanon , Jahns Lisa , Roemmich James , Hackney Kyle J.
Published: October 2019

Objective: We sought to determine whether daily protein intake and protein distribution across eating occasions were associated with functional disability in a national sample of older Americans. Methods: Data from 8,070 adults aged ≥60 years from the 2007-2016 waves of the National Health and Nutrition Examination Survey were included. Protein intake and functional capacity was self-reported. A daily protein recommendation of ≥1.0 g/kg/day was utilized. The daily protein recommendation was then spread-out across four meals, whereby a ≥0.25 g/kg/meal threshold was used. Results: Those meeting the daily protein recommendation had 0.78 (95% confidence interval [CI] = [0.65, 0.93]) decreased odds for functional disability. Persons meeting the protein intake threshold per eating occasion for one, two, three, and four occasions had 0.60 (CI = [0.38, 0.95]), 0.48 (CI = [0.30, 0.77]), 0.47 (CI = [0.29, 0.77]), and 0.39 (CI = [0.20, 0.75]) decreased odds for functional disability, respectively. Discussion: Protein consumption seems to be important for preserving function in older Americans.
Preservice and Inservice Teachers’ Perceptions of Pacing
Authors: Nápoles Jessica , Silveira Jason M.
Published: October 2019

The purpose of this study was to examine preservice and inservice teachers’ perceptions of pacing in ensemble rehearsal settings. We used Silveira’s definition of pacing as our conceptual framework: “the continuous flow of instruction without unnecessary interruptions and/or unnecessary sounds and without presentation of irrelevant material.” Participants were 23 preservice and 25 inservice music teachers. They viewed four excerpts of ensemble rehearsals and moved a Continuous Response Digital Interface dial to indicate their perceptions of fast and slow pacing. Based on our findings, we largely confirmed Silveira’s definition regarding pacing but suggest amending the definition for music rehearsal contexts to include student engagement and teacher talk. We propose the following revised definition of pacing: “the continuous flow of instruction without unnecessary interruptions and/or unnecessary sounds, without excessive teacher talk, and with presentation of relevant material while maintaining student engagement.”
Conflict and affiliative behavior frequency between cats in multi-cat households: a survey-based study
Authors: Elzerman Ashley L , DePorter Theresa L , Beck Alexandra , Collin Jean-François
Published: October 2019

Objectives

The objective of this study was to collect information from cat owners about the frequency of conflict and affiliative signs in their households in order to: (1) assess correlations with the owners’ ratings of household cat–cat harmony; and (2) determine if relationships exist between household variables, cat population variables and behavior frequencies.

Methods

Responses to an online survey of adult residents of the USA who were the primary caregiver of 2–4 indoor or indoor–outdoor cats were included in the analysis. Spearman’s correlations and χ2 tests were used to compare behavior frequencies with household and cat population variables.

Results

Of 2492 owners of multiple cats, 73.3% noted conflict signs from the very beginning when introducing the cats. The more cats in the house, the more frequent the conflict signs. Staring was the most frequently observed conflict sign, occurring at least daily in 44.9% of households, followed, in order of decreasing frequency, by chasing, stalking, fleeing, tail twitching, hissing and wailing/screaming. Hissing occurred at least daily in 18% of households. Affiliative signs were observed more frequently than conflict signs. Physical contact between cats was observed at least daily in around half of the multi-cat households. Higher harmony scores were correlated with less frequent conflict signs and more frequent affiliative signs. No household or cat population variable, including home size or numerically adequate resources provision, was strongly predictive of the frequency of conflict or affiliative signs.

Conclusions and relevance

This is the first large-scale online survey to obtain frequencies of conflict and affiliative behaviors and compare them with factors linked to the cats or the home settings. The study confirmed that feline relationships are correlated with the owner’s perceived impression of the initial introduction, but other household factors and cat population variables included in the study were not strongly predictive of the frequency of conflict or affiliative signs.
Examining the appointment of women to ministerial positions across Europe: 1970–2015
Authors: Goddard Dee
Published: October 2019

Under which circumstances are women appointed to ministerial positions? In this article, I provide a theoretical framework for the role of gender in ministerial selection by considering the policy, office, and vote-seeking motivations of party leaders. I present an original data set which details, at the party level, the appointment of female cabinet ministers in 30 European countries between 1970 and 2015. Using negative binomial regression models, I find that left-wing party leaders appoint more women than leaders of right-wing parties. Female party leaders appoint more women ministers than their male counterparts. Women are better represented in governments in gender-progressive countries, and survey data analysis shows that party leaders appoint more women when their supporters have more progressive gender attitudes. This analysis provides an original insight into how gender has shaped the partisan dynamics of ministerial selection across Europe over 45 years.
Novel approach for adaptive coefficient tuning for the simulation of evaporating high-speed sprays injected into a high-temperature and high-pressure environment
Authors: Nsikane DM , Vogiatzaki K , Morgan RE , Heikal M , Mustafa K , Ward A , Winder N
Published: October 2019

Producing reliable in-cylinder simulations for quick-turnaround engine development for industrial purposes is a challenging task for modern computational fluid dynamics, mostly because of the tuning effort required for the sub-models used in the various frameworks (the Reynolds-averaged Navier–Stokes and large eddy simulation). Tuning is required because of the need for modern engines to operate under a wider range of conditions and fuels. In this article, we suggest a novel methodology based on automated simulation parameter optimisation that is capable of delivering a priori a coefficient matrix for each operating condition. This approach produces excellent results for multiple comparison metrics like liquid and vapour penetration lengths, radial and axial mass fraction and temperature distributions. In this article, we also show for the first time that input model coefficients can potentially be linked to ambient boundary conditions in a physically consistent manner. Changes in injection pressure, charge pressure and charge density are considered. This paves the way for the tabulation of the constants in order to eliminate lengthy tuning iterations between operating conditions and move towards adaptive simulations as the piston moves changing the in-cylinder conditions. An additional discussion is performed for the validity range of existent models given that in recent years there has been a shift towards more extreme thermodynamic conditions in the injection stage (reaching the limits of transcritical flows). Although in this work the framework was implemented in the Reynolds-averaged Navier–Stokes context because this is the tool of preference of digital engineering currently by automotive industries, the approach can be easily extended in large eddy simulation.
Meta-Analysis on Interventions for Children Exposed to Intimate Partner Violence
Authors: Romano Elisa , Weegar Kelly , Gallitto Elena , Zak Sarah , Saini Michael
Published: October 2019

Several reviews have been conducted on children’s outcomes following exposure to intimate partner violence (IPV), but there remain inconsistent findings. We conducted a meta-analysis on child emotional and behavioral outcomes of IPV exposure interventions, based on published reviews that included a child component. We also explored relative effect sizes by examining moderators of the effect sizes across studies. This meta-analysis included 21 evaluation studies across 12 published reviews, which were located using a multiple database systematic search of English publications between 2000 and 2019. Studies were required to evaluate IPV interventions that included children, to gather quantitative pre- and post-intervention data on child outcomes, to use standardized instruments, and to present data in a format that could be used in a meta-analysis. Results indicated an overall pre- to post-intervention medium effect size ( d = 0.49), with effect sizes ranging from small to large depending on the specific outcome. Improvements at follow-up were maintained for internalizing behaviors but decreased for trauma-related symptoms and social, externalizing, and total behaviors. However, externalizing and total behavior outcomes still had significant effect sizes in the small-to-medium range ( d = 0.36 and 0.44). There were greater intervention effects when treatment was not exclusively trauma-specific. It appears that IPV exposure interventions are generally effective for improving children’s emotional and behavioral well-being, although interventions would benefit from greater tailoring to children’s specific needs. Interventions may also benefit from incorporating various content areas (both trauma-specific and non-trauma-specific) and from greater focus on ensuring the maintenance of treatment gains.
Effect of joint stiffness on torsional stiffness of open lattice composite structures
Authors: Shen Yang , Branscomb David , Adanur Sabit
Published: October 2019

In open lattice composite structures, the lattice components are chemically bonded, which affects the overall properties of the structure. This study examines the effects of chemically bonded joints on the torsional stiffness of tubular lattice composite structures. Tubular open lattice structures, known as the open-architecture composite structures, are manufactured by braiding the impregnated carbon fiber tows. Samples were prepared with no chemically bonded and with epoxy joints using braid angles of 35°, 45°, and 67.5°. A finite element model of the open-architecture composite structures is developed to examine the mechanical behavior under torsion. It is shown that there is a significant difference between the samples with no-bonding joints and samples with epoxy joints in terms of torsional stiffness. Torsional stiffness of the structure is retained at 97%, 96%, and 93% of the theoretical limit for 35°, 45°, and 67.5° braid angles, respectively, when joint stiffness is ten times the component stiffness. Torsional stiffness is only 32%, 22%, and 13% of the theoretical limit for 35°, 45°, and 67.5° braid angles, respectively, when joint stiffness is one-10th of the component stiffness. The epoxy bonding at the intersection achieves 72% of the theoretical torsional stiffness of the “perfect joint” for 45° braid angle when joint stiffness is equal to the component stiffness. The finite element model is validated by experimental results. It can be concluded from the finite element analysis and experimental testing that the stiffness of the bonding joints has significant impact on the overall torsional stiffness of the biaxial composite lattice.
Malignant Transformation of Hypertrophic Lichen Planus in a Young Pregnant Woman: A Case Report
Authors: Ravikumar Bharathi , Kumudhini S. , Krishnan S.
Published: October 2019

In this article, we report a case of hypertrophic lichen planus transforming into cutaneous squamous cell carcinoma in a 24-year-old Indian woman at 34 weeks of gestational age. We hypothesize that immunologic alterations during pregnancy could transform a long-standing hypertrophic lichen planus into cutaneous neoplasm.
A data-driven methodology for the classification of different liquids in artificial taste recognition applications with a pulse voltammetric electronic tongue
Authors: Leon-Medina Jersson X , Cardenas-Flechas Leydi J , Tibaduiza Diego A
Published: October 2019

Electronic tongue-type sensor arrays are devices used to determine the quality of substances and seek to imitate the main components of the human sense of taste. For this purpose, an electronic tongue-based system makes use of sensors, data acquisition systems, and a pattern recognition system. Particularly, in the latter, machine learning techniques are useful in data analysis and have been used to solve classification and regression problems. However, one of the problems in the use of this kind of device is associated with the development of reliable pattern recognition algorithms and robust data analysis. In this sense, this work introduces a taste recognition methodology, which is composed of several steps including unfolding data, data normalization, principal component analysis for compressing the data, and classification through different machine learning models. The proposed methodology is tested using data from an electronic tongue with 13 different liquid substances; this electronic tongue uses multifrequency large amplitude pulse signal voltammetry. Results show that the methodology is able to perform the classification accurately and the best results are obtained when it includes the use of K-nearest neighbor machine in terms of accuracy compared with other kinds of machine learning approaches. Besides, the comparison to evaluate the methodology is made with different classification performance measures that show the behavior of the process in a single number.
Multiple-model switching control for vibration suppression of planar membrane structures
Authors: Liu Mingjun , Huang Jin , Liu Mingyue
Published: October 2019

Membrane space structures have received widespread attention because of their small packaging volume and low mass. However, because membranes are very flexible and lightly damped, vibration suppression in membrane structures is very difficult. The objective of this study was to solve this problem. The first part of this article describes the influence of wrinkling in a membrane structure on the structure’s vibration characteristics. On this basis, the vibration deformations of a wrinkled square membrane structure were derived from the dynamic equations, and the correctness of this vibration model was verified by numerical simulation and experiment. A multi-model system is proposed to simulate the dynamic response of a membrane structure under different boundary conditions. In combination with the drive system, a multi-model switching control method based on adaptive and proportional–integral–derivative control is proposed. Under the initial disturbance, when the vibration amplitude dropped below 0.01 mm, the vibration duration was reduced to 2.96 s, compared with the duration of 12.37 s without control. The duration was shortened by approximately 39.7%, compared with the duration of 4.91 s achieved by the traditional proportional–integral–derivative control method, and by approximately 15.9% compared with the 3.52 s achieved by the out-plane control method. When there were multiple disturbances and the proposed method was used, the boundary displacement loadings did not increase when a certain value was exceeded. This prevented the breaking of the membrane by overstretching and provides a theoretical foundation for setting the initial pre-stress values.
The frontline of social prescribing – How do we ensure Link Workers can work safely and effectively within primary care?
Authors: Frostick Caroline , Bertotti Marcello
Published: October 2019

Objective

To identify the training, skills and experience social prescribing Link Workers, working with patients presenting with long-term conditions, need to carry out their role safely and effectively within primary care services.

Method

Qualitative data were collected from Link Workers as part of the evaluation of three social prescribing schemes. Interviews and focus groups were audio-recorded and transcribed.

Results

Link Workers describe the complexity of the work and the need to define the boundaries of their role within existing services. Previous life and work experience were invaluable and empathy was seen as a key skill. A variety of training was valued with counselling skills felt to be most critical. Clinical supervision and support were felt to be essential to conduct the work safely.

Discussion

Social prescribing is a significant theme within UK health policy and internationally and schemes in primary care services are common. Patient accounts consistently suggest that the Link Worker is key to the success of the pathway. Link Workers can facilitate positive behaviour change; however they must be recruited, trained and supported with a clear understanding of the demands of this complex role.
The relation between symmetry in food packaging and approach and avoidance words
Authors: Velasco Carlos , Pathak Abhishek , Woods Andy T , Corredor Andres , Elliot Andrew J
Published: October 2019

Research on aesthetic science has demonstrated that people generally prefer symmetrical over asymmetrical compositions. However, it remains unclear whether and how such compositions relate to the concepts of approach and avoidance motivation, especially in consumer contexts. In addition, it is not known how symmetry may influence such concepts in contexts where objects can differ in terms of their hedonic values (symmetry/product taste congruency). In the present research, we evaluated the relation between visual symmetry of the packaging of products with different hedonic value (sweet, non-sweet, non-food) and approach and avoidance words. In two experiments, we found evidence that people associate symmetrical designs with approach words more often than asymmetrical designs. Importantly, however, we did not find evidence that such an effect is influenced by the hedonic value of the products. Our results have value for scholars and practitioners interested in the effect of aesthetic features of brand elements (such as a product’s packaging) on consumer motivation.
Women of Reproductive Age Living with HIV in Argentina: Unique Challenges for Reengagement in Care
Authors: Cecchini Diego , Alcaide Maria Luisa , Rodriguez Violeta de Jesus , Mandell Lissa Nicole , Abbamonte John Michael , Cassetti Isabel , Cahn Pedro , Sued Omar , Weiss Stephen Marshall , Jones Deborah Lynne
Published: October 2019

This study evaluated the reasons for not taking antiretroviral treatment (ART) among women of reproductive age who are disengaged from HIV care (have missed pharmacy pickups and physician visits), with the goal of identifying strategies for reengagement in HIV care. Participants were cisgender women (n = 162), 18 to 49 years of age, and who completed sociodemographic, medical history, reasons why they were not taking ART, mental health, motivation, and self-efficacy assessments. Latent class analysis was used for analysis. Women who reported avoidance-based coping (avoid thinking about HIV) had higher depression ( U = 608.5, z = −2.7, P = .007), lower motivation ( U = 601, z = −2.8, P = .006), and lower self-efficacy ( U = 644.5, z = −2.4, P = .017) than those not using this maladaptive strategy. As women living with HIV experience a disproportionate burden of poor health outcomes, interventions focused on the management of depression may improve HIV outcomes and prevent HIV transmission.
Biomechanical Comparison of Quadriceps and 6-Strand Hamstring Tendon Grafts in Anterior Cruciate Ligament Reconstruction
Authors: Urchek Ryan , Karas Spero
Published: October 2019

Background:

The quadriceps tendon is becoming a popular graft option for anterior cruciate ligament (ACL) reconstruction. Few studies have examined the biomechanics of the quadriceps tendon compared with more commonly used graft choices. Due to the risk associated with small-diameter hamstring tendon grafts, various modifications of hamstring tendon preparation techniques have been described—specifically, a tripled, 6-strand hamstring tendon construct. This is the first study to directly compare the biomechanical properties of quadriceps tendon and hamstring tendon grafts.

Purpose/Hypothesis:

The purpose of this study was to quantify the biomechanical properties of the quadriceps tendon and 6-strand hamstring tendon grafts, specifically evaluating ultimate load to failure, load at 3 mm of displacement, and stiffness. These parameters characterize the time zero, in vitro, static tensile properties of these graft options. Our hypothesis was that for grafts of similar size, there would not be a significant difference in the biomechanical properties.

Study Design:

Controlled laboratory study.

Methods:

Quadriceps and hamstring tendon grafts were harvested from 6 human cadaveric knees (mean age, 61.17 ± 10.38 years). These matched grafts were prepared and biomechanically tested using an all-electric dynamic test load system. The mean diameter, stiffness, ultimate load to failure, and load to 3 mm of displacement were evaluated and analyzed.

Results:

The mean diameters of the 6-strand hamstring and quadriceps tendons were 11.33 and 10.16 mm, respectively ( P = .03). Despite these significantly different diameters, no differences were found in graft ultimate load to failure or load at 3 mm of displacement. The 6-strand hamstring tendon graft was significantly stiffer compared with the quadriceps tendon (1147.65 vs 808.65 N/mm; P = .04).

Conclusion:

The 6-strand hamstring tendon and quadriceps tendon graft had similar biomechanical properties with respect to ultimate load to failure and load at 3 mm of displacement in 6 matched cadaveric specimens. Both grafts were significantly stiffer than the native ACL, and the hamstring tendon construct was significantly stiffer than the quadriceps tendon.

Clinical Relevance:

The quadriceps tendon graft is a reliable alternative to a 6-strand hamstring tendon graft for ACL reconstruction.
Paradoxical Timelines in Wells Fargo’s Crisis Discourse: Expanding the Discourse of Renewal Theory
Authors: Anderson Lindsey B. , Guo Jiankun (Sylvia)
Published: October 2019

We detail the ways in which Wells Fargo used the tenets of the discourse of renewal and resilience communication to respond to its financial crises. To do so, we completed a thematic analysis of Well Fargo’s website and commercials. Specifically, we found that Wells Fargo relied on its organizational history to communicate renewal. In doing, so Wells Fargo (1) created a paradoxical timeline of events that puts alternative logic to work and (2) drew on established identity anchors. We therefore conclude that discourse of renewal can integrate past-orientation and address organizational identity work with theoretical basis. By combining these two frameworks and applying them to a real-world crisis context, we make important contributions to the continued development of both the discourse of renewal and resilience communication.
The Role of HR in Corporate Governance
Authors: Parker Marcel R.
Published: October 2019

In the era of epic disruption, HR has positioned itself as a strategic business partner, and in the fourth industrial revolution, it has taken up business priorities as its own to ensure business success. As agents of change for making people feel truly valued, six imperatives: Structure, Systems Selection/Succession, Separation, Standing Up and Safety form the pillars which sustain corporate governance and serve as the lodestar for the organisation. This article attempts to define the roles and responsibilities and rehumanise this function, keeping in mind the challenging conditions. The role of the employee and contracts are fast changing, and HR has to be able to confront and deliver around the 6 S’s for the future too.
Correction to: Synthesis and Characterization of Nanoscale Tungsten Particles with Hollow Superstructure Using Spray Drying Combined with Calcination Process
Authors: Zhao Panchao , Yi Wei , Cao Qigao , Zhang Bosheng , Chen Kunkun , Dang Rui , Chen Jialin
Published: October 2019

In the article [1], the use of the formula (NH4)6W7O24·6H2O to represent the starting material ammonium paratungstate (APT) is outdated and incorrect.
iTRAQ and PRM-based quantitative proteomics in early recurrent spontaneous abortion: biomarkers discovery
Authors: Cui Ying , He Ling , Yang Chun-Yan , Ye Qian
Published: October 2019

Background

Early recurrent spontaneous abortion (ERSA) is a common condition in pregnant women. To prevent ERSA is necessary to look for abortion indicators, such as hormones and proteins, in an early stage.

Methods

Thirty patients with ERSA were enrolled in the case group. In the control group, we recruited 30 healthy women without a history of miscarriage undergoing voluntary pregnancy termination. The differentially expressed proteins in the serum were identified between the two groups using PRM and iTRAQ.

Results

Seventy-eight differentially expressed proteins were identified. Using GO functional annotation and KEGG pathway analysis, we detected that the most significant changes occurred in the pathway of Fc gamma R-mediated phagocytosis. Meanwhile, using PRM, we identified three proteins that were closely related to abortion, B4DTF1 (highly similar to PSG1), P11464 (PSG1), and B4DF70 (highly similar to Prdx-2). The levels of B4DTF1 and P11464 were down-regulated, while the level of B4DF70 was up-regulated.

Conclusions

CD45, PSG1, and Prdx-2, were significantly dysregulated in the samples of ERSA and could become important biomarkers for the prediction and diagnosis of ERSA. Larger‑scale studies are required to confirm the diagnostic value of these biomarkers.
Correction to: “I just wish it becomes part of routine care”: healthcare providers’ knowledge, attitudes and perceptions of screening for maternal mental health during and after pregnancy: a qualitative study
Authors: McCauley Mary , Brown Abigail , Ofosu Bernice , van den Broek Nynke
Published: October 2019

Following publication of the original article [1], we have been notified of a few mistakes in the display of the author names. The publisher apologizes for the inconvenience.
The effect of mobilization with movement on pain and function in patients with knee osteoarthritis: a randomized double-blind controlled trial
Authors: Alkhawajah Hani A. , Alshami Ali M.
Published: October 2019

Background

Few studies have investigated the effects of mobilization with movement (MWM) in patients with knee osteoarthritis (OA) compared to other procedures. Sham procedures are generally more appropriate control than using no or usual treatments. Moreover, studies investigating the widespread hypoalgesic effects of MWM in patients with knee OA are lacking. The aim was to investigate the effect of MWM on function and pain in patients with knee OA compared to sham MWM.

Methods

This is a randomized double-blind (patients and assessor) controlled trial. Forty adult patients with knee OA of grade II and above were recruited to receive either MWM treatment or sham MWM for the knee. The outcome measures included the following: a visual analogue scale (VAS) for pain, the pressure pain threshold (PPT) test, the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index, the timed up and go (TUG) test, knee strength and knee range of motion (ROM). The measurements were taken at baseline, immediately after intervention and 2 days later.

Results

Compared with sham MWM, MWM resulted in greater immediate improvement in pain [mean difference (95% CI): − 2.2 (− 2.8, − 1.6)], PPT at both the knee [176 (97, 254)] and shoulder [212 (136, 288)], TUG time [− 1.6 (− 2.1, − 1.1)], knee flexor strength [2.0 (1.3, 2.7)] and extensor strength [5.7 (4.1, 7.2)] and knee flexion ROM [12.8 (9.6, 15.9)] (all, p < 0.001) but not knee extension ROM [− 0.8 (− 1.6, 0.1)] (p = 0.067). After 2 days of intervention, patients who received MWM also demonstrated a greater improvement in pain [− 1.0 (− 1.8, − 0.1)], PPT at the shoulder [107 (40, 175)], TUG time [− 0.9 (− 1.4, − 0.4)], knee flexor strength [0.9 (0.2, 1.7)] and extensor strength [2.9 (2.1, 3.9)] and knee flexion ROM [8.3 (4.7, 11.9)] (all, p ≤ 0.026). However, WOMAC scores and knee extension ROM showed no evidence of change at any stage after intervention (p ≥ 0.067).

Conclusions

MWM provided superior benefits over sham MWM in terms of local and widespread pain, physical function (walking), knee flexion and extension muscle strength and knee flexion ROM for at least 2 days in patients with knee OA.

Trial registration

ClinicalTrials.gov (NCT02865252), registered on August 12, 2016.
Psychological primitives can make sense of biopsychosocial factor complexity in psychopathology
Authors: Franklin Joseph C.
Published: October 2019

Background

Many agree that the biopsychosocial contributions to psychopathology are complex, yet it is unclear how we can make sense of this complexity. One approach is to reduce this complexity to a few necessary and sufficient biopsychosocial factors; although this approach is easy to understand, it has little explanatory power. Another approach is to fully embrace complexity, proposing that each instance of psychopathology is caused by a partially unique set of biopsychosocial factors; this approach has high explanatory power, but is impossible to comprehend. Due to deficits in either explanatory power or comprehensibility, both approaches limit our ability to make substantial advances in understanding, predicting, and preventing psychopathology. Thus, how can we make sense of biopsychosocial factor complexity?

Main text

There is a third possible approach that can resolve this dilemma, with high explanatory power and high comprehensibility. This approach involves understanding, predicting, and preventing psychopathology in terms of a small set of psychological primitives rather than biopsychosocial factors. Psychological primitives are the fundamental and irreducible elements of the mind, mediating all biopsychosocial factor influences on psychopathology. All psychological phenomena emerge from these primitives. Over the past decade, this approach has been successfully applied within basic psychological science, most notably affective science. It explains the sum of the evidence in affective science and has generated several novel research directions. This approach is equally applicable to psychopathology. The primitive-based approach does not eliminate the role of biopsychosocial factors, but rather recasts them as indeterminate causal influences on psychological primitives. In doing so, it reframes research away from factor-based questions (e.g., which situations cause suicide?) and toward primitive-based questions (e.g., how are suicidality concepts formed, altered, activated, and implemented?). This is a valuable shift because factor-based questions have indeterminate answers (e.g., infinite situations could cause suicide) whereas primitive-based questions have determinate answers (e.g., there are specific processes that undergird all concepts).

Conclusion

The primitive-based approach accounts for biopsychosocial complexity, ties clinical science more directly to basic psychological science, and could facilitate progress in understanding, predicting, and preventing psychopathology.
Kawasaki disease triggered by EBV virus in a child with Familial Mediterranean Fever
Authors: Maggio Maria Cristina , Fabiano Carmelo , Corsello Giovanni
Published: October 2019

Background

Familial Mediterranean Fever is a monogenic autoinflammatory disease, secondary to mutation of MEFV gene, and typically expressed with recurrent attacks of fever, serositis, rash, aphthous changes in lips and/or oral mucosa.

Kawasaki Disease, an acute systemic vasculitis with persistent fever (5 or more days), rash, stomatitis, conjunctivitis, lymphadenopathy, changes in extremities, is currently considered a multifactorial autoinflammatory disease.

An infection, as Epstein Barr virus, can be the trigger of Kawasaki Disease.

Case presentation

We describe the clinical case of a 3-year-old boy with Kawasaki disease. Successfully treated with intravenous immune globulin, acetyl salicylate acid, he late developed anaemia and thrombocytopenia. The Epstein-Barr virus infection has been demonstrated and he showed a resolution of the clinical manifestations of Kawasaki disease with the persistence of coronaritis, without aneurisms.

However, for the personal and familial history of monthly recurrent attacks of fever, pharyngitis, abdominal pain, the genetic study of MEFV was performed and demonstrated 3 heterozygous mutations of MEFV (E148Q, P369S, R408Q).

Conclusions

Mutations of MEFV can contribute to increase inflammatory expression in other diseases, as Kawasaki disease.
Characterization of genetic diversity on tropical Trichoderma germplasm by sequencing of rRNA internal transcribed spacers
Authors: Feitosa Yara Barros , Cruz-Magalhães Valter , Argolo-Filho Ronaldo Costa , de Souza Jorge Teodoro , Loguercio Leandro Lopes
Published: October 2019

Objective

Trichoderma species are found in soil and in association with plants. They can act directly or indirectly in the biological control of plant diseases and in the promotion of plant growth, being among the most used fungi in the formulation of bioproducts applied to agricultural systems. The main objective of this study was to characterize at a first-tier level a collection of 67 Trichoderma isolates from various tropical sources, based solely on sequencing of the internal transcribed spacer (ITS) region of the rRNA genes. Our goal was to provide a preliminary idea of the baseline diversity in this collection, to combine this information later with an array of other isolate-specific physiological data. This study provides a required knowledge at molecular level for assessment of this germplasm potential as a source of biotechnological products for beneficial effects in plants.

Results

Sequencing of the ITS region showed that the 67 Trichoderma isolates belonged in 11 species: T. asperellum, T. atroviride, T. brevicompactum, T. harzianum, T. koningiopsis, T. longibrachiatum, T. pleuroticola, T. reesei, T. spirale, T. stromaticum and T. virens. A total of 40.3% of the isolates were very closely related to each other and similar to T. harzianum. The baseline genetic diversity found indicates that the collection has different genotypes, which can be exploited further as a source of bioproducts, aiming at providing beneficial effects to plants of interest to cope with biotic and abiotic stresses.
A detailed overview of xylanases: an emerging biomolecule for current and future prospective
Authors: Bhardwaj Nisha , Kumar Bikash , Verma Pradeep
Published: October 2019

Xylan is the second most abundant naturally occurring renewable polysaccharide available on earth. It is a complex heteropolysaccharide consisting of different monosaccharides such asl-arabinose,d-galactose,d-mannoses and organic acids such as acetic acid, ferulic acid, glucuronic acid interwoven together with help of glycosidic and ester bonds. The breakdown of xylan is restricted due to its heterogeneous nature and it can be overcome by xylanases which are capable of cleaving the heterogeneous β-1,4-glycoside linkage. Xylanases are abundantly present in nature (e.g., molluscs, insects and microorganisms) and several microorganisms such as bacteria, fungi, yeast, and algae are used extensively for its production. Microbial xylanases show varying substrate specificities and biochemical properties which makes it suitable for various applications in industrial and biotechnological sectors. The suitability of xylanases for its application in food and feed, paper and pulp, textile, pharmaceuticals, and lignocellulosic biorefinery has led to an increase in demand of xylanases globally. The present review gives an insight of using microbial xylanases as an “Emerging Green Tool” along with its current status and future prospective.