bluuebunny/crossref_metadata_2025 huggingface dataset:
Kieszonkowy poradnik kierującego działaniem ratowniczym
Authors: Kielin Jan
Published: February 2025

Najnowsze wydanie Kieszonkowego poradnika kierującego działaniem ratowniczym bazuje na 10 edycji niemieckojęzycznego oryginału (M. Günter, R. Hermsen, M. Neuhaus, Feuerwehr-Einsatzleiter-Taschenbuch, Storck Verlag Hamburg 2022). To wodoodporna, kompaktowa publikacja, w której strażacy znajdą: rozmaite scenariusze zdarzeń, wskazówki dot. postępowania w obliczu różnych zagrożeń, przejrzyste informacje i schematy działań. W nowym wydaniu znalazła się nowość: niepublikowane dotąd i zaktualizowane karty ratownicze dot. postępowania podczas działań CBRNE, odesłania do materiałów informacyjnych KG PSP w postaci elektronicznej. Poradnik, popularny wśród niemieckich strażaków, powinien również dobrze służyć dowódcom jednostek OSP i PSP w Polsce, aby właściwie przeprowadzić działania ratowniczo-gaśnicze, zwłaszcza w niekorzystnych warunkach. Przedstawione hasła, szkice i tabele zostały wybrane przez autorów według najlepszej wiedzy i doświadczenia (….) Publikacja ta nie jest jednak podręcznikiem, który zastąpi właściwe zawodowe przygotowanie strażaków do wykonywania czynności ratowniczo-gaśniczych lub kierowania nimi. Jest to praktyczny poradnik, który każdego dnia może wspierać użytkownika przy realizacji zadań. Kolorystyka zastosowana do oznaczenia poszczególnych działów: Zagadnienia ogólne, Pożary, Ratownictwo techniczne i CBRNE ma na celu szybkie odnalezienie właściwej dla danej akcji ratowniczo-gaśniczej informacji. Natomiast odsyłacze prowadzą użytkownika kolejno do dalszych, możliwie istotnych sytuacji zagrożenia. Pierwsze wydanie Poradnika z 2017 roku spotkało się bardzo dużym zainteresowaniem. Nakład został wyczerpany. W odpowiedzi na zgłaszane nam potrzeby przekazujemy do sprzedaży zaktualizowaną i uzupełnioną wersję.
Testing the effect of changes in emotional distress on post-esophagectomy outcomes v1
Authors: Crump Trafford , Suarez Nisha , Kweon Jin
Published: February 2025

This study aims to investigate the impact of changes in preoperative emotional distress on postoperative outcomes in esophageal cancer patients undergoing esophagectomy. This is a retrospective study, using datacollected by McGill University’s Division of Thoracic Surgery. We will assess emotional distress at diagnosis and immediately prior to surgery using the Functional Assessment of Cancer Therapy-Esophageal (FACT-E) Emotional Well-Being subscale. We will categorize changes in emotional distress as 'improved' or 'unimproved' and analyze their association with postoperative length of hospital stay, complications, and 30-day readmission rates. This research seeks to determine whether preoperative psychological interventions could enhance surgical recovery and reduce healthcare utilization.
HCR - Embryo/Larvae fixation and permeabilisation v1
Authors: not provided FishFloorUCL
Published: February 2025

In situ hybridization chain reaction (HCR) is a method to visualize specific mRNAs in diverse organisms by applying a HCR that is an isothermal enzyme-free nucleotide polymerization method using hairpin DNAs. This specific protocol was developed by Chintan Trivedi based on previous work by Tsuneoka, Y. [1] and Choi [2]. It has many strengths over traditional (F)ISH: probe design is easier and doesn’t require optimisation or purification (contamination is not an issue), it is more specific (no off-target labelling), you can label up to six different targets in the same fish (multiplexing). Tsuneoka, Y. and H. Funato, Modified in situ Hybridization Chain Reaction Using Short Hairpin DNAs. Frontiers in Molecular Neuroscience, 2020. 13. Choi, H.M.T., et al., Third-generationin situhybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust. Development, 2018. 145(12): p. dev165753.
Differentiation of PSCs to Neural Progenitors v1
Authors: Dutan Polit Lucia , Nagy Roland
Published: February 2025

This protocol describes the differentiation of pluripotent stem cells (PSCs) to neural progenitors.
HCASMC CRISPRi TAPseq v1
Authors: Ramste Markus
Published: February 2025

This protocol outlines the steps for conducting a CRISPR interference (CRISPRi) TAP-seq experiment in human coronary artery smooth muscle cells (HCASMCs). The procedure includes virus transduction, MOI titration using digital PCR (dgPCR), and detailed instructions for setting up and running the experiment. Key steps involve configuring the experiment in the software, setting fluorescence thresholds for droplet analysis, and calculating target concentrations using the Poisson equation. The protocol ensures accurate quantification of target sequences and reference controls. This method provides a robust framework for analyzing gene expression and regulatory elements in HCASMCs using CRISPRi and TAP-seq technologies.
A Data‐Driven History of Gloucester's Fisheries Architecture
Authors: Santos Rafael Sousa , Tavares André
Published: February 2025

This article presents the methods and preliminary results of research into the socio‐ecological history of the Gloucester fisheries, with a focus on the interactions between humans and marine ecosystems. It explores how these interactions are reflected on land through the built environment and assesses the impact of human activity on marine life. The study is part of a broader research project examining the industrialization of fisheries along the North Atlantic coast. The objectives of this research are to establish a historical timeline of the Gloucester fisheries between 1880 and 1930, integrate statistical and geospatial data, and explore modalities for visualization and communication. Using a mixed‐methods approach, the study is organized around five datasets that combine written, statistical, and geospatial evidence: Fishing Grounds, Fishing Fleets, Population Shifts, Industry Footprint, and Processing Plants. Although the results are still inconclusive, this research aims to lay the groundwork for an experimental methodology that will be further developed. The goal is to enhance historical analysis by introducing an environmental perspective, assessing the pressures on ecosystems, and grounding the analysis in quantitative statistical and geospatial data.
Status‐Seeking Through Disaster Relief: India and China’s Response to Turkey–Syria Earthquakes
Authors: Jayaram Dhanasree , Gong Lina , Srivatsav Manaswini Dahagam
Published: February 2025

Disaster relief cooperation has emerged as an active area of status-seeking by major powers. In recent decades, India and China have increasingly leveraged their disaster management capabilities to project their power globally. Disaster relief cooperation can be viewed through the lenses of the logics of both appropriateness and consequences. As “non-Western” powers, they have conventionally been known to contest disaster relief norms perceived by them as Western. Simultaneously, they have varied status-seeking approaches, guided by distinct geopolitical equations and involving different actors. Against this background, the article analyses the patterns and drivers of India and China’s status-seeking behaviour through disaster relief cooperation using the frameworks of the logics of appropriateness and consequences, in the case of the 2023 Turkey–Syria earthquakes. It delineates the actors and capabilities involved in their overseas disaster relief activities as well as their implications. It also investigates the strategic and normative imperatives, and geopolitical considerations of their disaster relief cooperation. The article argues that the status-seeking behaviour of India and China through disaster relief cooperation with Turkey and Syria is guided by an interplay between the logic of appropriateness and the logic of consequences, based on their motivations, capacities, and distinct contexts of the recipient countries.
THE PARADIGM OF THE IDEA OF GLOBAL DIGITAL GOVERNANCE AS A PHENOMENON OF ADMINISTRATIVE LAW
Authors:   Public Organization “Analysis Center of Air and Space Law”, Levchenko Diana
Published: February 2025

The purpose of the article is to conducting a conceptual analysis of the paradigm of the idea ofglobal digital governance as a phenomenon of administrative law.Methods. The article uses the method of dialectics to reveal the digital revolution as a prerequisitefor the idea of global digital governance; the method of theoretical synthesis regarding the study of basic management paradigms (traditional, digital) and the formation of a conceptual model ofglobal digital governance; and the method of legal phenomenology in determining the main legalphenomena generated by the digital revolution and their relationship with administrative law.Results. The article defines the digital revolution as a prerequisite for the idea of global digitalgovernance. The digital revolution is revealed as a transformation of management processesat the global level. The stages of formation of the concept of global digital governance fromtraditional governance, electronic and global digital governance are determined. Global digitalgovernance is identified as a natural phenomenon of the development of administrative law in theconditions of globalization.Conclusions. The work revealed that the digital revolution of the 20th century is a prerequisitefor the idea of global digital governance as a new concept of global administration. Thedigital revolution, which has become a catalyst for the idea of global digital governance, is atechnological phenomenon and a civilizational shift that prompts a review of traditional legalstructures, approaches to decision-making and ensuring transparency in governance. It isestablished that the digital revolution has created the prerequisites for the formation of a new typeof governance, in which information technologies are the main tool for achieving public interests.It was revealed that the digital revolution has created a unique opportunity for the integration ofdifferent-level administrative processes, ensuring effective access to services and establishing aconnection between the government and society. It is revealed that global digital governance asa phenomenon forms a new legal reality in which the integration of technologies becomes a keyelement of effective public management and administration.
Immanuel Kant and theatre: to the problem statement
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Korobko Margaryta
Published: February 2025

Background. On the occasion of the 300th anniversary of Immanuel Kant, this study is dedicated to exploring his influence on theatrical art, even though Kant himself did not show much interest in theater. The article attempts to examine the theater of his time, its presence in Königsberg, and the impact of Kant's philosophy on the development of theatrical theory. To study the relationship between German theatrical art of the 18th century and the philosophy of Immanuel Kant, as well as to explore the influence of his philosophical ideas on the development of theatrical art in general.

Methods. The article employs general scientific methods such as analytical, comparative, and generalization.

Results. The analysis of Immanuel Kant's influence on theatrical art is an atypical area of philosophical research. Although Kant did not leave any works specifically dedicated to theater, his aesthetic theories, particularly those presented in "the Critique of Judgment", had a significant impact on the development of theatrical art and its theory. Kant's ideas, especially his concepts of the beautiful and the sublime, influenced Romanticism and notable figures such as Friedrich Schiller and Johann Goethe. The article also explores the historical context of theater development in Königsberg, where Kant lived and worked. Special attention is given to Kant's role in establishing aesthetic ideas that became the foundation for subsequent changes in theatrical art. The article emphasizes that Kant's philosophy remains relevant and influential in contemporary theater, providing new tools for analyzing and understanding aesthetic ideas. When considering the social role of theater and theatrical art, Kant also emphasized the importance of social interaction in the creation of art. He viewed aesthetic judgment as a serious act that is not merely private but concerns all of humanity. Aesthetic judgments form a public sphere, making them an important subject for philosophical analysis. According to Kant, aesthetic judgment is a way of seeking truth that unites people into a common human community. Similarly, theater is an instrument for seeking truth, a platform for questioning and finding answers to relevant issues. The article also highlights Kant's significance for understanding theater as an art form that unites different types of creativity and reveals its potential for fostering aesthetic taste and moral values.

Conclusions. Due to the lack of studies on the connection between Kant's philosophy and theatrical art, there is a vast field for analyzing his influence on the aesthetics of theater, as confirmed by the history of theater during his lifetime.
The picture frame: an aesthetic study (Translated from German by Olena Pavlova)
Authors: Simmel Georg , Pavlova Olena ,   Humboldt University of Berlin
Published: February 2025

The translation is supported by the Gerda Henkel Foundation from the publication: Simmel, G. (1902). Der Bildrahmen - Ein ästhetischer Versuch. Der Tag. Nr. 541, 18. November 1902 (Berlin).
MORPHOLOGICAL RESULTS OF INTRAOSSEOUS OSTEOINTEGRATION OF TITANIUM IMPLANTS WITH Ag- AND Zn-CONTAINING CALCIUM PHOSPHATE COATINGS
Authors: Irina А. Kirilova Irina А. Kirilova , Maiborodin Igor V. , Maiborodina Vitalina I. , Sheplev Boris V. , Sharkeev Yuri I P. , Sedelniko Mariya B. , Pavlov Vitaliy V. , Bazlov Vyacheslav A. , Anastasieva Evgeniya A. , Efimenko Maxim V.
Published: February 2025

INTRODUCTION: The surface condition of the implanted structures plays an important role in increasing the service life of implants and metal structures in the human body. Modification of implant surfaces is of great importance not only for traumatology and orthopedics, but also for restorative medicine, bone oncology, dentistry and maxillofacial surgery.
RESEARCH PURPOSE. To study in an experiment the effect of titanium implants with a calcium phosphate coating containing zinc or silver ions on surrounding bone tissues in an experiment.
METHODS. Using light microscopy, we studied the condition of bone tissue in the proximal tibia (PTB) of rabbits 4 weeks after implantation of cone-shaped titanium 3D implants with a rough surface of a calcium phosphate coating containing zinc or silver ions.
RESULTS. In all cases, titanium 3D implants with a patterned rough surface implanted in the PFB adhered very tightly to the bone tissue, the edges of which had minor cicatricial changes. Removal of the implants was difficult, many tissue fragments remained on their surface. Small foreign fragments were present in the bone tissue samples studied.
CONCLUSION. Titanium implants with a modified surface have demonstrated a tendency to osseointegration, even when the coating is damaged with the formation of foreign fragments migrating into the surrounding tissues. It is possible that changing approaches to the technique and modes of coating application and varying their thickness will allow the positive properties of the modified surface to be realized in full, including the positive antimicrobial properties of silver and zinc.
DESIGN OPTIMIZATION OF FIBER GLASS FILLER CIRCULAR CRASH BOX UNDER FRONTAL LOADING MODEL
Authors:   Doctoral Student of Mechanical Engineering Department, University of Brawijaya, WIDJANARKO DR. , CHOIRON MOCH. AGUS ,   Mechanical Engineering Department, University of Brawijaya, PURNOWIDODO ANINDITO ,   Mechanical Engineering Department, University of Brawijaya, IRAWAN YUDY SURYA ,   Mechanical Engineering Department, University of Brawijaya
Published: February 2025

This study aims to optimize the design parameters of a fiberglass filler circular crash box to enhance Energy Absorption (EA) capabilities under frontal loading conditions. Utilizing Response Surface Methodology (RSM) and a Box-Behnken Design (BBD), the research comprises 15 experiments to assess the impact of three primary parameters: foam diameter, foam height, and aluminum tube thickness. The optimal configuration achieved a maximum EA of 45.6002 kJ. The findings indicate that foam height significantly influences EA, and the interaction between foam height and tube thickness is crucial for optimizing crash box performance. This research also reveals significant interactions among design parameters, contributing to improved vehicle safety standards and crashworthiness. Consequently, the study underscores the importance of design optimization in enhancing vehicle safety, reducing the necessity for extensive physical testing, and ensuring effective energy dissipation during collisions. The results provide valuable insights for the future development of vehicle safety technologies.
ULTRASONIC PULSATING WATER JET DRILLING- PRELIMINARY STUDY
Authors:   Faculty of Manufacturing Technologies TUKE with a seat in Presov, STOLARIK GABRIEL , NAG AKASH ,   VSB - Technical University of Ostrava, KLICHOVA DAGMAR ,   The Czech Academy of Sciences, Institute of Geonics, HLOCH SERGEJ ,   The Czech Academy of Sciences, Institute of Geonics
Published: February 2025

This study presents pioneering experiments utilizing an ultrasonic pulsating water jet (PWJ) for drilling into aluminum alloy 5.5 mm thick following a circular trajectory with a diameter of 6 mm. The innovative approach combines the high frequency of water pulses with frequency of 20 kHz impinging the surface of material at Bernoulli impact speed was 254 m/s to enhance drilling efficiency and observe drilling precision. Circular trajectories with 10, 15 and 20x transition provided basic information on the characterization of the erosion process and the factors entering the process. Finally, an 80x multiple repetition confirmed the complete cutting of the sample and the separation of the core material from the surrounding material. The research provides a foundational understanding of UPWJ technology's potential applications in environmentally clean manufacturing processes.
EVALUATION OF EROSION RESISTANCE OF ADDITIVE 3D PRINTED MATERIALS UNDER CONTINUOUS AND PULSATING WATER JET EXPOSURE
Authors:   Faculty of Mechanical Engineering, VSB - Technical University of Ostrava, PETRU JANA , SKOREPA RADIM ,   Faculty of Mechanical Engineering, VSB - Technical University of Ostrava, NAG AKASH ,   Faculty of Mechanical Engineering, VSB - Technical University of Ostrava, STOLARIK GABRIEL ,   Faculty of Manufacturing Technologies, Technical University of Kosice with a seat in Presov, HLOCH SERGEJ ,   Institute of Geonics, The Czech Academy of Sciences
Published: February 2025

Additively manufactured/printed represent a high potential for their use in various branches of technical practice. However, their applicability requires knowledge of the maximum application limits, or the intensity of their damage due to external factors. This article investigates the testing of 3D printed materials produced via Selective Laser Melting (SLM) treated by an ultrasound excited pulsating water jet (PWJ). The study focuses on two frequencies, 20 kHz and 40 kHz, applied to AISI 316L stainless steel and AlSiMg10 aluminium alloy. The time exposure ranged from 0.5 seconds to 10 seconds, with increments of 0.5 seconds. The water jet was pressurized to 40 MPa using a high-pressure pump, and a nozzle with a diameter of 0.4 mm was employed. The primary objective of this research is to explore the effects of ultrasonic excitation on the erosion characteristics and surface integrity of SLM-manufactured materials. The results showed that both the time exposure and the modulation frequency play vital role in determining erosion depth. Also, the surface conditions of the material are significant in erosion magnitude. Therefore, by systematically varying the exposure time and frequency, the study provided a comprehensive understanding of how these parameters influence the erosion evolution and performance of the tested materials.
COBALT-FERROUS RATIOS FOR ENHANCED CORROSION AND WEAR RESISTANCE OF ELECTRODEPOSITED COATINGS ON 316 STAINLESS-STEELS
Authors:   Department of Mechanical Engineering, Vel Tech Rangarajan Dr, Sagunthala R&D Institute of Science and Technology, KUMAR J.V. SAI PRASANNA , R. SUNDHARESAN ,   Department of Mechanical Engineering, Vel Tech Rangarajan Dr, Sagunthala R&D Institute of Science and Technology, KRYSKA DOMINIK ,   Department of Machining, Assembly and Engineering Metrology, Faculty of Mechanical Engineering, VSB-Technical University of Ostrava, CEP ROBERT ,   Department of Machining, Assembly and Engineering Metrology, Faculty of Mechanical Engineering, VSB-Technical University of Ostrava, SAMAL S.P. ,   Department of Biosciences, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences
Published: February 2025

This study investigates the enhancement of wear and corrosion resistance of 316 stainless steels through Co-Fe electrodeposited coatings at varying ratios (50:50, 75:25, 95:5). The 50:50 Co-Fe ratios produced a uniform, defect-free coating with a thickness of 35 µm and a body-centered cubic (BCC) microstructure. Electrochemical tests, including Tafel and Nyquist plots, revealed superior corrosion resistance for the 50:50 ratio, with a low corrosion rate of 0.0037 mm/year, a corrosion potential (Ecorr) of -259.534 mV, and a corrosion current density (Icorr) of 12.752 µA. Tribological evaluation indicated the highest wear resistance, with the longest wear time (1082 seconds) and the lowest coefficient of friction (0.29). These findings highlight the potential of Co-Fe coatings for aerospace and marine applications, particularly in components exposed to harsh mechanical and corrosive environments. The study also emphasizes the novelty of cyclic voltammetry as a precise method for optimizing electrodeposited coatings.
A SYSTEMATIC LITERATURE REVIEW ON THE IMPACT OF GENERATIVE AI ON ADDITIVE MANUFACTURING: CURRENT STATE AND FUTURE DIRECTIONS
Authors:   Faculty of Data Science, University of Finance - Marketing, TRUONG THANH-CONG , HAI THUY TRUONG DINH ,   Faculty of Data Science, University of Finance - Marketing, KHANG NGUYEN HUY ,   Faculty of Data Science, University of Finance - Marketing, MA QUOC-PHU ,   Department of Machining, Assembly and Engineering Metrology, Faculty of Mechanical Engineering, VSB-Technical University of Ostrava, PETRU JANA ,   Department of Machining, Assembly and Engineering Metrology, Faculty of Mechanical Engineering, VSB-Technical University of Ostrava
Published: February 2025

Artificial Intelligence (AI) and its applications in modern industry, particularly in additive manufacturing (AM), have garnered significant attention from both researchers and industry professionals. In recent years, the rise of generative AI (GenAI) models, marked by the launch of ChatGPT in 2022, has driven an unprecedented shift in industry practices and workforce dynamics. This paper investigates the current state of research at the intersection of GenAI and AM, while also exploring future directions. By conducting a keyword search across four major databases (Web of Science, Scopus, IEEE Xplore, and ScienceDirect), we collected 272 papers. Through an in-depth evaluation of these papers, we identified five primary themes shaping GenAI applications in AM: AM process optimization, generative design, data & quality, design workflow, and applications. This paper also provides a detailed analysis of each category, offering valuable insights into the evolving role of GenAI in AM.
STATISTICAL EVALUATION OF CUTTING FORCE COMPONENTS AS A FUNCTION OF CUTTING EDGE RADIUS SIZE FOR MILLING OF AUSTENITIC STAINLESS STEEL AISI 316L
Authors:   Slovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava, Centre of Excellence of 5-axis Machining, Vozar M. , Vopat T. ,   Slovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava, Centre of Excellence of 5-axis Machining, Jurina F. ,   Slovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava, Centre of Excellence of 5-axis Machining, Patoprsty B. ,   Slovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava, Centre of Excellence of 5-axis Machining
Published: February 2025

This study investigates the impact of cutting edge radius on cutting forces during machining of AISI 316L with uncoated cemented carbide tools. Four cutting edge radii were tested, each with three tools. Milling was conducted with different parameters for roughing and finishing. Cutting forces were measured and analyzed into tangential and radial components. Statistical evaluation using linear regression and analysis of variance assessed the influence of edge radius, machining conditions, and interactions. Results showed that both edge radius and machining conditions significantly affect cutting forces, providing insights for optimizing tool selection and improving tool life under various conditions.
A COMPARATIVE ANALYSIS OF THE DIGITIZATION OF GEOMETRIC OBJECTS FABRICATED VIA ADDITIVE FDM TECHNOLOGY WITHIN THE FRAMEWORK OF REVERSE GEOMETRIC MODELLING APPLICATIONS
Authors:   Slovak University of Technology, Faculty of Materials Science and Technology, Dubnicka M. , Buransky I. ,   Slovak University of Technology, Faculty of Materials Science and Technology, Kritikos M. ,   Slovak University of Technology, Faculty of Materials Science and Technology
Published: February 2025

Additive manufacturing is already a commonly used manufacturing method encountered in industry. With the increasing demands for precision manufacturing, the need for reverse engineering also needs to be addressed. The aim of this study is to compare the results of digitizing primitive geometric objects using a coordinate measuring machine (CMM) and industrial computed tomography (CT) in terms of reverse geometric modeling. The principles of reverse geometric modelling are applied to samples produced by additive Fused Deposition Modelling (FDM) in order to create a geometrically accurate 3D CAD model from the acquired data. In the experiment, curves obtained from primitive geometric objects such as a cylinder were compared. 5 curves were obtained from each object. These curves were fitted to a nominal curve and the resulting curve dimension was compared with respect to the data acquisition method used.
The results of the study showed comparable accuracy of the two data acquisition methods. The investigated diameters were in tolerance of 40 +- 0.15 mm and thus correlated with the STN EN 2768 - 1 standard for nontoleranced surfaces. The individual data can be used to speed up the creation of 3D CAD models improving the accuracy and quality of these models.
A prospective study on identification, assessment, and spontaneous reporting of adverse drug reactions at a tertiary care hospital
Authors: Gurung Aruna , Ramaiah Balakeshwa
Published: February 2025

Background: Adverse drug reactions (ADRs) significantly contribute to global morbidity and mortality. Voluntary ADR reporting is crucial for the Pharmacovigilance Programme of India (PvPi), which identifies and quantifies medication risks. This study monitors ADRs from various departments of a tertiary care hospital, assessing them for causality, preventability, and severity before reporting to the Indian Pharmacopoeia Commission (IPC).
Methods: This prospective study was conducted over six months at a tertiary care hospital, which is an approved ADR Monitoring Centre (AMC). Data was collected by PharmD students, who assessed each ADR for causality, severity, and preventability using the World Health Organization (WHO) scale, Hartwig’s severity scale, and Schumock and Thornton scales. Descriptive statistics were used for analysis.
Results: A total of 358 suspected ADRs were evaluated. Most reactions (87.98%) were classified as "moderate" in severity, with 45.53% considered not preventable. The majority of ADRs were categorized as probable (84.07%), with Class J drugs (Anti-infectives) being the most associated (29.89%). Most reports came from General Medicine (53.35%), and the primary affected organ systems were metabolic and nutritional (21%).
Conclusions: Most ADRs in this study were caused by antimicrobials, highlighting the need for careful prescribing and patient monitoring. Type A ADRs were often underreported, with healthcare professionals focusing primarily on Type B and H reactions. This study emphasizes the importance of voluntary ADR reporting and the vital role of clinical pharmacists in assessing and documenting these reactions.
Evaluation of adverse drug reactions in a tertiary care hospital in India
Authors: James Janet M. , Paul Eldho M. , Varghese Dinu , John Jibin , Kuriakose Alan , Pillai Abhirami B. , Pramoj Shilpa , Chand O. Aparna
Published: February 2025

Background: Adverse drug reaction (ADR) is a major concern in the healthcare system and has been a persistent issue in the health sector. This study aimed to evaluate and assess the ADRs reported, the system organ class (SOC) affected, seriousness, outcomes, causality.
Methods: A retrospective observational study in a tertiary care hospital from April 2021 to May 2024. A descriptive analysis of reactions, causality of suspected drugs was carried out according to the setting analysed.
Results: Out of 7,396 individual case safety report (ICSR) reported, the highest number of ADRS was reported in the age group of 18-65 years (57.8%) and male patients (51.1%). Using World Health Organization-Uppsala Monitoring Centre (WHO-UMC) causality assessment scale, 67.1% events were possible. A significant majority of drug reported as ‘certain’ were of anti-infective class (51.03%). Most frequently affected SOC was blood and lymphatic system disorders (15.9%), Of all events, greater part of the reactions was non-serious (95.3%), the most drugs causing ADRs was anti neoplastic and immunodulating agents (40.4%) and 47.2% of drugs were high alert medications. The greater part of ADRs reporting was carried out by clinical pharmacists (95.9%).
Conclusions: The results highlighted the importance of clinical pharmacist in monitoring and spontaneous reporting of ADRs. Awareness and educational programs may help in active reporting among all healthcare providers.
Diagnostic accuracy of ultrasound in common shoulder pathologies: a retrospective cohort study and literature review
Authors: Mohamed Osama , Sam Jerry , Pydah Satya Kanth , Cheema Kanwalnaini
Published: February 2025

Background: This study aims to evaluate the diagnostic accuracy of shoulder ultrasound in detecting common shoulder pathologies, including rotator cuff tears, AC joint diseases, glenohumeral joint diseases, subacromial impingement, and long head of biceps conditions. The research question focuses on comparing ultrasound findings with arthroscopy results.
Methods: We conducted a retrospective cohort study of 60 patients who underwent preoperative ultrasound followed by shoulder arthroscopy. Sensitivity, specificity, and diagnostic accuracy were calculated for each pathology, comparing ultrasound to arthroscopic findings.
Results: Ultrasound demonstrated high sensitivity (90%) for detecting rotator cuff tears but showed lower sensitivity and specificity for AC joint diseases, subacromial impingement, and glenohumeral joint diseases. Ultrasound was particularly limited in identifying early biceps tendon pathologies.
Conclusions: Ultrasound is highly sensitive for diagnosing rotator cuff tears and serves as a valuable initial diagnostic tool. However, it is less reliable for other shoulder pathologies, where additional imaging modalities may be needed to confirm diagnoses. Improved operator training could enhance diagnostic accuracy.
Outcome of closed intramedullary fixation of femoral shaft fracture by titanium elastic nail in children
Authors: Uddin M. Minhaz , Islam Tasmia , Hossain M. Sharif , Rashid M. Harun Are , Bose Barshan , Rana M. Sohel
Published: February 2025

Background: Femoral shaft fractures are most common fractures in paediatric orthopaedic age group. The best treatment between six to fourteen years of age is a matter of debate. Titanium flexible elastic intramedullary nailing has become a well-accepted method of treatment of paediatric femoral shaft fractures. This study aims to evaluate the functional outcome of treatment of femoral shaft fracture by closed intramedullary titanium elastic nail (TEN) in children age between 6 to 14 years.
Methods: This prospective observational study was conducted over a period of two years from July 2017 to June 2019. Thirty children (23 boys, 7 girls) aged 6-14 years with femoral diaphyseal fractures were stabilized with retrograde titanium elastic nail. The results were evaluated by using Flynn’s TEN scoring criteria. Two nails were used in each fracture.
Results: Mean age was 11.1±1.8 years with male female ratio 3.3:1. Male patients were predominant in this study. Type of fracture were observed that 10(33.3%) cases were oblique, 18 (60.0%) cases were transverse and spiral 2 (6.7%). Radiological union in all cases were achieved in a mean time of 9.6±1.9 weeks. Objective evaluation showed that 21 (70.0%) patients had knee flexion >130°, 7 (23.3%) had restricted motion of 120–130°, and 2 (6.7%) had a range of 100–120°. The results were excellent in 23 patients (76.7%), satisfactory in 7 patients (23.3%) and there was no poor result.
Conclusions: TEN fixation of paediatric femoral shaft fractures is an excellent method of treatment in children aged 6-14 years.
Outcome of the treatment of developmental dysplasia of the hip after walking age with open reduction, varus derotation osteotomy with femoral shortening and acetabular osteotomy
Authors: Mahmud Al-Imran , Noman Saifullah Al , Minto M. C. Paul
Published: February 2025

Background: The principles of treatment of developmental dysplasia of hip after walking age are different than those of infants and neonates. The purpose of this study is to evaluate the radiographic and functional results of open reduction, varus derotation osteotomy with femoral and acetabular osteotomy of DDH in older children.
Methods: Between March 2021 and August 2023, 22 patients underwent one-stage triple procedure of open reduction, varus derotation osteotomy with femoral shortening and acetabular osteotomy for the treatment of DDH. Clinical outcomes were assessed using the modified McKay’s criteria. Radiographic assessment was made using Severin’s scoring system.
Results: The mean age at the time of operation was 5.068±1.8535 years (range 3–8 years) with male to female ratio 1:2.66. Mean preoperative acetabular index of the study population was 48.55±7.63 which significantly reduced to 23.68±2.93 postoperatively (p<0.05). The McKay’s score was excellent in 14 (63.6%) hips, good in 02 (9.1%) hips, fair in 01(4.5%) and poor in 05(22.7%) hips. The modified Severin’s class excellent was in 14 (63.6%) hips, good was in 02(9.1%) hips, fair is in 01 (4.5%) hip and poor was in 05 (22.7%) hips at the time of final evaluation as compared to none at the time of presentation.
Conclusions: Young children having DDH can be safely treated with an extensive one-stage procedure of open reduction, varus derotation osteotomy with femoral shortening and acetabular osteotomy, without increasing the risk of AVN. This one-stage surgical procedure for managing DDH patients after walking age also revealed acceptable clinical and radiological outcome.
Effectiveness and cost-utility of lumbar facet joint blocks using bupivacaine with and without steroid in the treatment of chronic low back pain in adults
Authors: Aeerabolli Ajay Reddy
Published: February 2025

Background: Chronic low back pain (LBP) causes lot of pain and suffering thus contributing to frequent and increased cost and burden on health-care-facilities. In United Kingdom, it has been estimated that economic cost of LBP pain is around £12.3B per annum. It is also associated with increased incidence of depression, anxiety. These morbidities also lead to increased costs for patient. To study effectiveness and cost-utility of lumbar facet joint blocks using bupivacaine with and without steroid in the treatment of chronic LBP in adults.
Methods: Hospital-based randomized comparative study was carried out among 100 adult cases of chronic LBP. They were randomly assigned as 50 cases treated with bupivacaine without steroids and 50 cases treated with bupivacaine with steroids. Modified oswestry disability index was used to assess functional improvement and visual analogue scale to assess pain score. Patient data was used to assess cost-utility.
Results: Patients in group-II were significantly older, had more pain duration than group-I. Incidence of repeat procedure required was more in group-I compared to group-II (p<0.05). The functional level in both groups was comparable (p>0.05) at baseline. At one, three, six and twelve months, it improved more significantly in group-II compared to group-I (p<0.05). At baseline, pain score was significantly more in group-II compared to group-I (p<0.05). But, at one, three, six and twelve months, it was significantly lesser in group-II compared to group-I (p<0.05). Patients in both groups were comparable for physician cost and facility cost. But total number of procedures and average number of treatments per patient were lesser in group-II compared to group-I.
Conclusions: Thus, we conclude that bupivacaine with steroids is not only effective in relief of pain and returning normal functionality, but also cost-effective compared to bupivacaine without steroid in adult patients with chronic LBP.
Comparative analysis of suprapatellar vs infrapatellar approaches in intramedullary nailing for distal tibia fractures
Authors: Ojha Ankur , Pushprajan  , Maheshwari Prince , Singh Ajit
Published: February 2025

Background: The current study delves into the clinical and functional outcomes of suprapatellar (SP) and infrapatellar (IP) intramedullary nailing techniques in treating distal tibia fractures, utilizing data accrued from King George’s Medical University, Department of Orthopaedics, between Jan 2022 to August 2023.
Methods: A retrospective analysis was carried out involving two groups of patients who underwent either SP or IP nailing techniques. Several parameters including surgical time, blood loss, pain score and functional outcomes were evaluated. Functional outcomes were assessed on the basis of AOFAS scores.
Results: The SP group demonstrated a reduced mean surgical time (85.7±14.8 minutes) compared to the IP group (96.3±16.7 minutes, p=0.011). Moreover, the SP group reported lower pain scores (20.2±3.9) than the IP group (27.5±3.6, p<0.001) and exhibited better functional outcomes as evidenced by higher AOFAS scores (94.1±4.3 vs 88.5±4.7, p<0.001). However, no significant difference was noted in blood loss or fracture healing time between the two groups.
Conclusions: The study underscores the potential superiority of the suprapatellar approach in terms of reduced surgical time, lower pain scores and better functional outcomes. Despite this, the infrapatellar approach had a higher incidence of fracture deformities, necessitating a cautious approach when selecting surgical strategies. Further research with larger sample sizes is warranted to substantiate these preliminary findings.
A pulmonary embolism secondary to fracture tibia: a clinical case report
Authors: Singh Jaswant , Saketh
Published: February 2025

Pulmonary thromboembolism (PTE) occurs when a thrombus, typically originating from venous thromboembolism, obstructs the pulmonary arteries, disrupting blood flow to the lungs. The thrombus often becomes lodged at the bifurcation of the main pulmonary artery or within the lobar branches, causing hemodynamic instability. Although the thrombus most commonly originates in the lower extremities as deep vein thrombosis (DVT), it can occasionally arise from the pelvic veins, renal veins, upper extremity veins, or the right side of the heart. Various factors can contribute to the development of deep vein thrombosis, but in the context of long bone fractures, it Deep vein thrombosis (DVT) typically develops 7 to 10 days after an injury. However, in rare cases, pulmonary thromboembolism (PTE) has been observed within 72 hours of the trauma. Several theories have been proposed to explain the mechanisms behind the early onset of PTE in such instances. Presenting a case which involves a 34-year-old male who developed pulmonary thromboembolism (PTE) following a roadside accident, and had segmental closed fracture of the right tibial shaft.
Experiencias de formación de grado en gestión editorial: el caso de la revista Informatio (Uruguay)
Authors: Vázquez Marcela , Fuster Yanet
Published: February 2025

Introducción: Actualmente no existe en la carrera ningún espacio específi co donde se focalice con detenimiento en el campo editorial, lo que entendemos muy necesario en la formación de los profesionales de la información. En virtud de este escenario, constatamos la necesidad de integrar a la formación espacios donde la gestión editorial se presente de forma más específi ca. Debido al lugar que posee la revista Informatio, en tanto publicación que pertenece a la Facultad de Información y Comunicación, hemos decidido sumar a las vertientes de la revista, un espacio que aporte a la formación de los futuros bibliotecólogos. Las prácticas pre profesionales (PPP) contempladas en nuestro plan de estudios constituyen el camino desde donde la revista puede ser espacio de encuentro de saberes y experiencias para formar a los estudiantes.Objetivo: El objetivo de esta presentación es mostrar la actividad de formación que se desempeña en la revista, compartiendo el constructo teórico que la impulsa, y las vertientes que orientan la practica propiamente dicha.Metodología: Brindaremos algunos lineamientos acerca de los contenidos de las prácticas, y las implicancias que a nivel pedagógico se desarrollan a partir del planteo realizado.Conclusiones: El resultado de la práctica refl ejado en los documentos propuestos por los estudiantes, evidencia que las expectativas planteadas en un inicio, se colmaron
Presença das revistas científicas do portal de periódicos da UFRGS nas redes sociais online
Authors: Krummenauer Anne , Tirello Acquolini Nicole , Andréa de Souza Vanz Samile
Published: February 2025

Analisa a presença das revistas científicas do Portal de Periódicos Científicos da Universidade Federal do Rio Grande do Sul em redes sociais não-acadêmicas. A pesquisa documental foi realizada no Facebook, Instagram, LinkedIn, X e Youtube, coletando dados sobre a criação dos perfis, alcance potencial e quantidade de postagens. Dos 44 títulos do Portal, 23 revistas mantêm 49 perfis nas redes analisadas. Os perfis têm, em média, 5,5 anos de existência, alcance de 67.719 seguidores e realizaram 12.017 postagens. O Facebook é a rede que concentra mais seguidores e perfis mais antigos. Os resultados desta pesquisa apresentam um mapeamento da situação das revistas publicadas pela UFRGS, e permitirão apoiar estratégias para expandir seu alcance e divulgação, bem como ajudar as revistas na estruturação da equipe para criação de novos perfis e manutenção dos perfis já existentes.
Presencia de revistas científicas del portal de revistas de la UFRGS en redes sociales en línea
Authors: Krummenauer Anne , Tirello Acquolini Nicole , Andréa de Souza Vanz Samile
Published: February 2025

Analiza la presencia de revistas científi cas del Portal de Revistas Científicas de la Universidade Federal do Rio Grande do Sul en redes sociales no académicas. La investigación documental se realizó en Facebook, Instagram, LinkedIn, X y Youtube, recopilando datos sobre la creación de perfiles, el alcance potencial y el número de publicaciones. De los 44 títulos del Portal, 23 revistas tienen 49 perfi les en las redes analizadas. Los perfi les tienen una antigüedad promedio de 5,5 años, un alcance de 67 719 seguidores y 12 017 publicaciones. Facebookes la red que concentra el mayor número de seguidores y los perfi les más antiguos. Los resultados de esta investigación presentan un mapeo de la situación de las revistas editadas por la UFRGS, y permitirán apoyar estrategias para ampliar su alcance y difusión, así como ayudar a las revistas a estructurar sus equipos para crear nuevos perfi les y mantener los existentes.
Lucia Engombe, a Namibian “GDR-Child No. 95”
Authors: Balezin Alexander
Published: February 2025

Lucia Engombe is one of more than 400 Namibian “GDR children” — the children of fighters of the Namibian liberation movement SWAPO, who were adopted by the GDR for upbringing and training in 1979—1989. She was brought to this country from a refugee camp in Zambia in 1979, and she lived and studied there until 1990, when all the Namibian children were returned to their homeland. However, she is not quite an ordinary “GDR child”, due to the complexities of her parents’ fates. Her father was in opposition to the SWAPO leadership and was considered a traitor, and her mother, after studying at a Moscow university, became close to SWAPO leader Sam Nujoma. This left its mark on the views of Lucia herself. In her memoirs, which served as the main source for this article, one can find information and considerations that differ from the memoirs of other “GDR children”. She is critical of the SWAPO and its efforts to transform the “GDR children” into the future elite of independent Namibia, to GDR indoctrination in the spirit of building socialism. She is preoccupied with the problems of her own identity, and at different stages of her life she sees them in different ways. In independent Namibia, Lucia Engombe's fate was difficult, she did not join the “new elite” of the country, and at critical moments she was helped by “capitalists” — German farmers and charitable foundations from Germany. The life of Lucia Engombe and other “GDR children” reveals a number of interesting aspects in the problem of cultural transfer, which occupies the minds of many modern historians.
Lesotho Prime Minister Leabua Jonathan: the Dynamics of Image Change in the Soviet Press in the 1960s — 1980s (based on Materials from the Newspapers Pravda and Izvestia)
Authors: Voevodskiy Alexander
Published: February 2025

The article analyses the dynamics of changes in the image of Lesotho Prime Minister Leabua Jonathan (1966—1986) in the Soviet press. The significance of this topic is due to the historical context of the period under study — in the 1960s — 1980s. Lesotho was an important center of the national liberation struggle in Southern Africa. Many members of the ANC and PAC found refuge on its territory in the 1960s, and from here the activities of the ANC underground were coordinated in the second half of the 1970s — mid-1980s. The figure of Leabua Jonathan naturally occupied a central place in these events, which is confirmed by his posthumous award of the Order of the Companions of Oliver Tambo in 2007 — one of the highest awards of South Africa. An analysis of the main newspapers of the USSR, Pravda and Izvestia, also allows us to study strategies for forming Soviet readers’ ideas about the national liberation struggle in Africa, adopted in the Soviet press.