bluuebunny/crossref_metadata_2025 huggingface dataset:
Alkaline phosphatase-to-albumin ratio as a novel predictor of long-term adverse outcomes in coronary artery disease patients who underwent PCI
Authors: Dai Xin-Ya , Zheng Ying-Ying , Tang Jun-Nan , Wang Wei , Guo Qian-Qian , Yin Shan-Shan , Zhang Jian-Chao , Cheng Meng-Die , Song Feng-Hua , Liu Zhi-Yu , Wang Kai , Jiang Li-Zhu , Fan Lei , Yue Xiao-Ting , Bai Yan , Zhang Zeng-Lei , Zheng Ru-Jie , Zhang Jin-Ying
Published: June 2021

Background: Alkaline phosphatase (ALP) and albumin (ALB) have been shown to be associated with coronary artery disease (CAD), and it has been reported that alkaline phosphatase-to-albumin ratio (AAR) is associated with the liver damage and poorer prognosis of patients with digestive system malignancy. Moreover, several previous studies showed that there was a higher incidence of malignancy in CAD patients. However, to our knowledge, the relationship between AAR and long-term adverse outcomes in CAD patients after undergoing percutaneous coronary intervention (PCI) has not been investigated. Therefore, we aim to access the relation between AAR and long-term adverse outcomes in post-PCI patients with CAD.

Methods: A total of 3378 post-PCI patients with CAD were enrolled in the retrospective Clinical Outcomes and Risk Factors of Patients with Coronary Heart Disease after PCI (CORFCHD-ZZ) study from January 2013 to December 2017. The median duration of follow-up was 37.59 ± 22.24 months. The primary end point was long-term mortality including all-cause mortality (ACM) and cardiac mortality (CM). The secondary end points were major adverse cardiac events (MACEs) and major adverse cardiac and cerebrovascular events (MACCEs).

Results: Kaplan–Meier analyses showed that an increased AAR was positively correlated with incidences of long-term ACM (log-rank, P=0.014), CM (log-rank, P=0.011), MACEs (log-rank, P=0.013) and MACCEs (log-rank, P=0.006). Multivariate Cox regression analyses showed that the elevated AAR was an independent predictor of long-term ACM (adjusted HR = 1.488 [1.031–2.149], P=0.034), CM (adjusted HR = 1.837 [1.141–2.959], P=0.012), MACEs (adjusted HR = 1.257 [1.018–1.551], P=0.033) and MACCEs (adjusted HR = 1.237 [1.029–1.486], P=0.024).

Conclusion: An elevated AAR is a novel independent predictor of long-term adverse outcomes in CAD patients following PCI.
Ecological Intervention for Stuttering in School-Age Children: A Collaborative Approach for School-Based Speech-Language Pathologists and Mental Health Providers
Authors: Hoff Steven E. , Unger Julia P.
Published: June 2021

Purpose

Stuttering can have a significant detrimental effect on the overall well-being of children, including anxiety, stigma, and adverse impact on the development of healthy social relationships. This clinical focus article proposes a collaborative, ecological model of stuttering intervention consistent with interprofessional practice that combines the expertise of the speech-language pathologist and school-based mental health provider to support fluency and social–emotional health for school-age children who stutter. The literature in the fields of speech pathology and mental health interventions was summarized to provide the underlying evidence base for such a collaborative approach.

Conclusions

While collaborative approaches are recommended as best practice for stuttering, there is scant evidence in the literature of such approaches being used. An ecological, collaborative framework will enable practitioners to help teachers, parents, and others address speech disfluency as well as the accompanying anxiety and avoidance that are pervasive in the lives of many children who stutter. Such an approach will help ensure that gains in the treatment room are carried across settings (i.e., transfer/generalization of skills) and will help children be better able to manage the challenges associated with stuttering to find success in the real world.
Diagnosing gait disorders based on angular variations of knee and ankle joints utilizing a developed wearable motion sensor
Authors: Akhavanhezaveh Ardalan , Abbasi‐Kesbi Reza
Published: June 2021

Here, a sensory motion system is developed to diagnose gait disorders using the estimation of angular variations in the knee and ankle joints. The sensory system includes two transmitter sensors and a central node, where each transmitter comprises three sensors of accelerometer, gyroscopes, and magnetometer to estimate the angular movements in the ankle and knee joints. By using a proposed filter, the angular variation is estimated in a personal computer employing the raw data of the motion sensors that are sent by the central node. The obtained results of the presented filter in comparison to an actual reference illustrate that the root mean square error is less than 1.01, 1.34, and 1.61 degrees, respectively, for the angles of and and that illustrate an improvement of 40% than the previous work. Moreover, a quantity value is defined based on the correlation between knee and ankle angles that show the amount of correctness in gating. Thus, the proposed system can be utilized for people who suffer problems in gait and help them to improve their movements.
Scattering of an obliquely incident E− polarised plane wave from ensembles of slotted cylindrical cavities: A rigorous approach
Authors: Vinogradova Elena D. , Smith Paul D.
Published: June 2021

A rigorous theory is developed for the multiple scattering analysis of an polarised plane wave from an ensemble of 2‐D slotted arbitrary cylinders. The Method of Analytical Regularisation, previously applied to the solution of scattering wave problems for isolated slotted cylinders, is generalised to problems incorporating ensembles of closed or slotted cylinders. Numerical calculations of the complex eigenvalues, factors and resonant current densities are performed for various configurations of two slotted circular or elliptical cavities, focussing on an accurate assessment of differing peculiarities of the mutual resonant electromagnetic coupling.
Simulating the Galactic multi-messenger emissions with HERMES
Authors: Dundovic A. , Evoli C. , Gaggero D. , Grasso D.
Published: June 2021

Context. The study of nonthermal processes such as synchrotron emission, inverse Compton scattering, bremsstrahlung, and pion production is crucial to understanding the properties of the Galactic cosmic-ray population, to shed light on their origin and confinement mechanisms, and to assess the significance of exotic signals possibly associated to new physics.

Aims. We present a public code called HERMES which is designed generate sky maps associated to a variety of multi-messenger and multi-wavelength radiative processes, spanning from the radio domain all the way up to high-energy gamma-ray and neutrino production.

Methods. We describe the physical processes under consideration, the code concept and structure, and the user interface, with particular focus on the python-based interactive mode. In particular, present the modular and flexible design that allows the user to easily extend the numerical package according to their needs.

Results. In order to demonstrate the capabilities of the code, we describe the details of a comprehensive set of sky maps and spectra associated to all physical processes included in the code. We comment in particular on the radio, gamma-ray, and neutrino maps, and mention the possibility of studying signals stemming from dark matter annihilation.

Conclusions. HERMES can be successfully applied to constrain the properties of the Galactic cosmic-ray population, improve our understanding of the diffuse Galactic radio, gamma-ray, and neutrino emission, and search for signals associated to particle dark matter annihilation or decay.
Experimental Study on Wind Erosion of Concrete Building Surface in Wind-Sand Environment
Authors: Jia Ying , Pei YuFei , Xie ZhiWei
Published: June 2021

In this paper, the effects of different wind-sand attack angle, wind speed, action time, concrete strength, sand particle size, and sand content on the surface wind erosion of concrete structures are experimentally studied. Wind erosion rate and strength loss rate are defined as the indexes to measure the degree of wind erosion of concrete. According to the similarity theory, the actual situation is deduced based on the wind erosion test, and the wind erosion time corresponding to the wind speed, the action time of wind sand, and the simulation test in the case of sand content is obtained. it makes the experimental study of wind erosion on concrete buildings to have more practical significance.
Study on sandstorm in the western section of Hexi Corridor of 2020
Authors: Wang Haiyan , Tian Qingming , Zhu Caixia
Published: June 2021

A diagnostic analysis of the dust storm weather occurring in the western part of the Hexi Corridor from 27-30 June 2020 was carried out using Jiuquan city’s live data, as well as ECMWF numerical forecasts, and the NCEP reanalysis information was used to draw a theta dust storm model based on the routing principle. The results show that: 1.In the early stage of sandstorm, there was no precipitation in Suzhou and Jinta counties in March and April, which resulted in dry surface and thickened soil layer. These factors created favorable conditions for the occurrence of dust weather. 2.Development of unstable trough eastward in front of the ridge of Mountain Ural at 500 hPa, The cold high pressure is continuously strengthened in the process of moving, which is the large-scale system leading to the sandstorm. Thermal depression in front of ground cold front is the main cause for the outbreak of the severe sandstorm. 3.The beginning and ending time of the sandstorm can be accurately predicted by the simulation chart of sandstorm forecast, which has a good indication significance for the sandstorm forecast in the Hexi area.
Study on the design of landscape wall of Wuhan Garden Expo
Authors: Cai Jing , Mo Yulong , Zhang Xinyang , Yuan Yimin
Published: June 2021

The investigation on the landscape wall of Wuhan Garden Expo shows that the landscape wall of Wuhan Garden Expo is widely used. There are four types of landscape wall, cultural wall, retaining wall and logo wall. There are 42 landscape walls in 34 Urban gardens. Their forms and themes of expression are different in Wuhan Garden Expo. Most of the landscape walls in Wuhan Garden and Expo Garden are made of marble materials, which show the characteristics of multi-color collocation in color. The size of the landscape walls is often determined by the content of the expression. The composition of the landscape walls is usually designed with plants.
Life cycle carbon emission of monorail transit and its comparison in operation stage with other city transit modes
Authors: Li Teng , Zhu Eryu , Liu Haoran
Published: June 2021

In this paper, carbon emissions of a monorail transit are calculated using the method of whole life cycle, which can be divided into four stages: material manufacturing stage, construction stage, operation stage and demolition stage. In the operation phase, the units are PKT (Passenger Kilometers Travelled) and VKT (Vehicle Kilometers Travelled), while in other three stages, the unit is 1 km. The results show that the carbon emissions from the 1km length monorail are 6271.204 tons. In addition, in the operation stage, it is found that the PKT index and VKT index of Chongqing monorail transportation are 0.07468 and 3.31933 respectively, far lower than those of subways in the same city. For PKT indicators of other rail transits, from small to large, they are light rail, tram, subway, APM and maglev. As for VKT indicators, from small to large, they are tram, light rail, subway, APM and maglev. The PKT index of Beijing subway is the lowest compared with that of other cities.
The optimization design of Piled raft foundation for substation building in US code
Authors: Yang Qingtao , Chen Ying , Li Wei , Wei Xiao , Gan Xing
Published: June 2021

In order to get a more safety and economic foundation, finite element method was performed for a piled mat cap and piled strip cap by the software of STAAD. Through the finite element analysis, plate distribution region of bending moment and shear stress were researched; meanwhile, considering the compatibility of deformation of element plate, how to chose the design value of plate stress was researched. The result showed that: single plate value is not representative, average of value of 9 plates (3x3 array) is close to the fact. Strip cap is better than mat cap both from the moment value and shear value of plate element in this project; strip cap was recommended due to its remarkable economic benefit.
A Research About One-dimensional Chloride Ion Erosion In Concrete Under Drying-wetting Cycles
Authors: Shen Hang , Li Jinyuan , Chen Changyuan , Li Yongli , Ji Wenjun
Published: June 2021

Reinforced concrete structures are now widely used in China, and with the exploitation of marine resources, many concrete structures are in a relatively harsh service environment. Concrete in wave and tidal stream areas is in a dry and wet cycle state. When unsaturated concrete is in a dry and wet cycle state, chloride ions will invade the concrete by diffusion and convection, which accelerates the erosion of the reinforcement within the concrete and degrades the concrete performance. Therefore, the study of chloride ion erosion in concrete under dry and wet cycles is particularly important. Fick’s law is a good predictor of the diffusion of chloride ions in saturated concrete with stable boundaries, but it is difficult to obtain satisfactory results for concrete under dry and wet cycles. There are many difficult parameters in the microscopic model that make programming the calculations more difficult. In this paper, we propose to use the radial basis function matching point method to solve the problem. It is found that the error is within acceptable limits and can be used to calculate the one-dimensional erosion of chloride ions under dry and wet cycles through solving the validation algorithm.
Research on the development of green buildings under the high-speed development mode
Authors: Zhu Shihan , Liu Jingjing , Wu Chenjie
Published: June 2021

In the rapid development of science and technology today, environmental problems are becoming more and more serious; the construction industry as the first high energy-consuming field with human production and life, the promotion of green buildings is of great significance. Under the high-speed development mode, how to make green buildings develop steadily has become a problem to be solved by various industries in China. Through the literature research method and the social investigation method, this paper analyses the development constraints of green buildings from the perspective of the four participants of market economy: government, real estate enterprises, consumers and practitioners. Respectively put forward some suggestions such as policy regulation, enterprise norms, green talents cultivation and collect feedback.
Study of water quality analysis and evaluation of Hengshui Lake
Authors: Gao Yuhua , Li Haihua , Zheng Yuxuan , Guo Ruhui , Liu Zhenfa
Published: June 2021

The water quality of Hengshui Lake in different regions and at different times was analyzed. According to the data analysis results of chemical oxygen demand (COD), biochemical oxygen demand (BOD5), ammonia nitrogen (NH3-N), total nitrogen (TN), total organic carbon (TOC), total phosphorus (TP), calcium ion content, total hardness, chloride ion content, pH value and conductivity of Hengshui Lake water samples, the water quality of Hengshui Lake was evaluated and analyzed. The results showed that the pollution of Hengshui Lake was mainly organic matter pollution, especially non-biodegradable organic matter pollution. The value of TN was higher than the Class III water, which showed that the self purification capacity of Hengshui Lake water body was weaker. The water quality of Hengshui Lake was better, but the treatment of organic pollution should be paid attention to.
Effect of total solids contents on the performance of anaerobic digester treating food waste and kinetics evaluation
Authors: Zhao Xiao-Fei , Yuan Yan-Qi , Chen Qing-Kong , Li Qi , Huang Yan , Wu Di , Li Lei
Published: June 2021

The effects of total solids (TS) content on the performance of anaerobic digestion (AD) treating food waste (FW) and kinetic characteristics were investigated in mesophilic batch reactors. The results showed that FW could be digested normally in the AD system within the TS of 3%-30%. The volume methane yield of dry-AD increased by 5.2-10.6 times than that of wet-AD and the degradation time of unit substrate was shortened by 35%-71%. The system stability indicators of dry-AD, such as pH, VFA/TA, TAN and salt remain within the suppression threshold after digestion. dry-AD had obvious advantages. The kinetic analysis showed that ADM1 could be used to simulate the anaerobic digestion reactor of FW, and accurately simulated the methane production in different TS systems after calibrating. With the increase of TS, the hydrolysis and methane production showed a tendency to increase first and then decrease, but the decrease rate of hydrolysis was higher than that of methanogene. Increasing TS simultaneously weaken the hydrolysis rate and methanation rate, but the effect on the hydrolysis and acidification phase weaker. The ratio of the hydrolysis rate constant to the methanogenic Monod maximum specific absorption rate (khy/km_ac) was a new perspective to used to evaluate the balance between the hydrolysis stage and the methane production stage. The results show that the khy/km_ac ratio of the 15% TS and 20% TS experimental groups was close to 1. It can be speculated that the system TS between 15%-20% can be used as recommended value in anaerobic digestion engineering design to treat FW. Within this TS range, hydrolysis and methane production dynamics matching, the accumulation of inhibitors is also in a relatively moderate state in the threshold.
Mesoscale modelling of bond failure behaviour of ribbed steel bar and concrete interface
Authors: Liu Mengjia , Zhang Renbo , Jin Liu , Du Xiuli
Published: June 2021

To explore the nonlinear bond behaviour between ribbed bar and concrete, combined with the characteristics of concrete meso-structure and ribbed bar surface characteristics and considering frictional resistance and the mechanical interlocking between rebar and concrete, a meso-scale model is established. Based on the good agreement between the simulation results and experimental results, the failure mechanism of bond between rebar and concrete is discussed, and the distribution characteristics of bond stress of steel bar are analysed. Furthermore, based on the meso numerical analysis method, the influence of friction coefficient between rebar and concrete on the failure mode of concrete and bond stress-slip curve was discussed, and the proportion of friction component in bond strength is obtained.
Research on the influence of design parameters on mechanical performance of net arch bridge
Authors: Cao Xinke , Lu Zheyuan , Hao Xianwu , Yang Guojun
Published: June 2021

In order to study the suspender layout parameters and design parameters of the tied arch bridge with mesh suspenders under the action of vehicle load, the structure stress is more reasonable and meets the higher economy and aesthetics. Taking a 96m span reticulated tied arch bridge as the engineering background, the finite element model is established by using Midas/Civil 2019 program. The variation law of internal force and Suspender Force of the structure is calculated and analysed under the change of rise span ratio and suspender number parameters, and the relatively optimal value range of corresponding parameters is given. The results show that the rise span ratio should be 0.2-0.24; The number of Suspenders for one side arch rib should be 34-38; The relatively optimal range of the above parameters is discussed for reference.
The construction technology and finite element analysis of the whole lifting of large grid
Authors: Deng Deyuan , Zhang Weixiong , Li Zixuan , Li Guangjun , Mo TianFang , Chen Zhou , Lu Hanwen
Published: June 2021

Taking a large grid frame in a maintenance hangar of Guangzhou Baiyun Airport as the research object, the construction steps of lifting the grid structure are briefly described, and the static mechanical characteristics, dynamic mechanical characteristics and stability of the large grid frame were studied by using Midas/Civil finite element analysis software, which meets the design and the practical application requirements. Since its first six orders safety factors are greater than 4. The stress state of the nodes at the important supports in the grid is mainly controlled by axial force.
Effect of water-to-binder ratio and fly ash content on the mechanical and deformation properties of bendable concrete
Authors: Du Jg , Chen B , Yang Yn , Bai Y , Wang Xf , Ao J , Zhong Ar , Zhang Dy
Published: June 2021

To investigate the effect of water-to-binder ratio and fly ash content on the properties of bendable concrete, we prepared four samples of different strength grades with water-to-binder ratios of 0.25 and 0.30 and fly ash contents of 60% and 80%. The effects of water-to-binder ratio and fly ash content on the compressive strength, flexural strength, elastic modulus, fracture toughness, and uniaxial tensile deformation of the samples were investigated. The results show that the strength of bendable concrete can be varied by varying the water-to-binder ratio and fly ash content. Water-to-binder ratio and fly ash content showed almost the same effect on fracture toughness, whereas fly ash content exhibited a greater effect on elastic modulus. With an increase in water-to-binder ratio and fly ash content of concrete, the initial crack stress and tensile strength decreased and the ultimate tensile strain increased, but the change of water-to-binder ratio showed a more significant effect on the ultimate tensile strain.
Research on the properties of peat soil and foundation treatment technology
Authors: Wang Xingkuo , Cao Xiuling , Xu Haiyan , Zhang Siru , Gao Yunsheng , Deng Zixiong , Li Jianming
Published: June 2021

In the infrastructure construction of my country and the countries along the “Belt and Road”, there are many projects involving peat soil foundation treatment, but there is a lack of in-depth research on the properties of peat soil and foundation treatment technology, and there is no complete set of relevant foundation treatment technical specification systems. However, the traditional replacement method for ground treatment characteristics cannot meet the needs of energy saving, environmental protection and green development concepts. This article adopts the method of literature research, taking Sri Lanka (CKE project) as an example to introduce the engineering foundation treatment technology of peat soil in detail, and provide a reference for the construction and treatment of peat soil foundation. How to realize the technical problem of peat soil-based treatment needs to be solved urgently, so the understanding of peat soil requirements is beneficial in the long term.
Study on construction control system of continuous rigid frame bridge with corrugated steel webs
Authors: Lu Z. Y. , Cao X K , Zhang J D
Published: June 2021

In order to improve the management and control level of bridge construction and understand the real-time dynamics of bridge construction in real time, a set of cloud 3D visualization information management and control system is created based on the Internet platform. In view of the characteristics of high precision and great difficulty in the construction control of corrugated steel webs bridge, a set of construction control and control software based on B/S (browser/server) architecture is developed to help managers know the site structure state more intuitionistic and improve the efficiency of construction control and control. The system deeply integrates the two-dimensional plane information with the three-dimensional entity, and realizes the three-dimensional display of information flow by highly restoring the real bridge construction state in the three-dimensional scene. The results show that the system can assist the management personnel to carry out construction management and improve the engineering efficiency through linear prediction. The system can realize the dynamic demonstration of the long span CSW-PC continuous rigid frame bridge 3D model and the graphical display of the construction measurement and control data and progress information.
The importance of applying the principle of sustainable development in trade
Authors: Pavicevic Djordjije , Novicevic Rajko , Abramovic Nikola , Crvenica Dejana
Published: June 2021

The relevance of this paper stems from the fact that the concept of sustainable development is just beginning to be applied in Montenegro. The state of Montenegro and its government are actively implementing strategies related to sustainable development, especially in areas where Montenegro has potential, such as agriculture and similar industries. The topic of this master ’s thesis is focused on the analysis of sustainable development in trade, with a special aspect on domestic products. This paper aims to show how in reality the goals of sustainable development have contributed to the improvement of business within trade, adapting trade to the needs of consumers of the 21st century and how they have provided the basis for better trade development in the future to maintain environmental, economic and consumer prosperity. Trade is just one of the areas in which sustainable development operates, but it greatly affects the economy itself, human habits and behavior.
The utilization of Social Media in marketing the Lebanese Higher Education institutions
Authors: Ismail Fadia
Published: June 2021

In today’s competitive environment, it is significant to develop a strong community that retains existing customers and attracts new ones. Higher education institutions in Lebanon, given the pandemic, are shifting to online platforms to market their services. The article explains how HEIs in Lebanon use social media as a way of engaging and communicating with stakeholders. Using a questionnaire targeting the marketing department of the Lebanese HEIs, managerial and marketing implications will be presented to explain the promotional implications of using social media and its challenges. The findings showed that most Lebanese higher educational institutions are utilizing social media strategies when planning their marketing efforts, due to the fear of losing control of its reputation and the limited budget allocated for these efforts. Moreover, they have a limited understanding of its value and its implications and, thus, use it solely for communication purposes with their current and potential students, rather than showing what they do as research centers.
HR-manager: Prospects for Employment in the Labor Markets
Authors: Zhukovska Valentyna , Piatnytska Galyna , Raksha Natalia , Lukashova Liudmyla , Salimon Olha
Published: June 2021

Topical issues of changing the requirements for HR managers in the labor market under the Covid crisis and digital transformation of business have been highlighted. Attention is drawn to the main responsibilities of a modern HR manager. The problems of communication interaction in the work of HR managers through the transition of employees to online or mixed mode of operation have been identified. An analysis of the supply and demand of HR managers in the labor market of different countries has been conducted. The requirements and benefits for HR manager by the sample of countries have been compared. Particular attention is paid to the work of HR-managers with expats. Distinctive characteristics of an expat in the position of HR manager have been demonstrated. In 2020-2021, the survey of HR managers has been conducted and the skills of the HR manager, which will enable him to be strategically in demand in the labor market and to contribute to the progressive development of both national and international companies have been identified. The objective of the paper is to identify transformations in the work of modern HR-managers and analysis of supply and demand for HR.
Education for sustainable development in the perspectives of “Information society”
Authors: Lipin Mykola , Husieva Nataliia , Krasilnikova Olena
Published: June 2021

Sustainable development aims at transforming existing way of development, which is gradually moving towards our planet’s ecosystem destruction and hypertrophied economic growth at the cost of other social life areas. In this paper, we prove that sustainable development of society implies changing methods of development themselves. The aim of this paper is to study possibilities and prospects for implementing principles of sustainable development in education sector, which essence is understood as developing ways of development and thinking themselves. To achieve this goal, dialectics is used as general theory of development, specifically its distinctive ability to differentiate qualitative, essential development from quantitative growth, quantitative transition within one essence. This paper proves that sustainable development is impossible without radical transformation of ways of activity, production, thinking and world perception. In this context, alternative potential, represented by “information society” models, is analyzed. Considering that desired model of sustainable development of society should not be only abstract ideal, it is proved that it might and should be embodied in daily practical activities today. Education as an area for intersubjective interaction where development of human subjectivity takes place has always been not only sector fulfilling existing society demands but also anticipating future society opportunities.
Social business as a component of controlling’s accounting support in trade enterprises
Authors: Kostyuchenko Valentyna , Kamil Anastasiia , Petrov Pavlo , Kolot Liubov
Published: June 2021

The disclosure of information about social business of trade enterprises is usually associated with some issues like alternative formats of presenting information (non-financial GRI reporting, managerial report, integrated report), lack of unified requirements for recognition of social business, their evaluation, scope and analytical disclosure of information, formation of data about social business in the system of controlling’s accounting support in trade enterprise. The purpose is to deepen the theoretical foundations and substantiate the proposals for the formation of controlling’s accounting support in trade enterprise by creating a strategic map in the context of social business. The dialectical method, methods of induction and deduction, scientific abstraction, comparative characteristics, economic and statistical methods were used in the research process. The formation of controlling’s accounting support in the trade enterprises in accordance with the goals of sustainable development will solve problems related to new social challenges, reduce systemic risk, increase brand value, increase sales and will build the trust of customers and society.
Indicators for assessing state fiscal policy in the context of promoting sustainable development
Authors: Sushkova Olena , Нurochkina Viktoriya , Voroshilo Viktoria , Tumanova Elena
Published: June 2021

The article proposes a scientific and methodological approach to assessing the level of promotion of fiscal policy of sustainable development, uniting a set of indicators of realization in the country of 17 SDGs. Applying the principle of the hierarchy of diagnostic knowledge, the assessment of the level of support for fiscal policies for sustainable development is presented through the linguistic variable, with the separation of measures of influence on the economic, social and environmental blocs. The hierarchical relationship between the state parameters and the level of support for fiscal policies for sustainable development is graphically presented as a logical inference tree The approach has been tested by measuring the level of promotion of fiscal policies for sustainable development in Ukraine for two scenarios, This will make it possible to predict the impact of the country’s policies. According to the results of the study, it has been proved that the level of support for the fiscal policy of sustainable development in Ukraine suppresses the implementation of 17 SDGs, and the nature of the changes tends to a pessimistic development scenario, and the total index for promoting fiscal policies for sustainable development decreases annually.
Scientific and practical aspects of extremal situations development in environmental and socio-economic frames of Ukraine and the European Union
Authors: Tkachenko Tetiana , Hladkyi Oleksandr , Zhuchenkо Valentyna , Bilyk Vladyslav
Published: June 2021

The theoretic fundamentals of the geography of extremal situations as a new approach for environmental science and socio-economic investigations are disclosed. The new direction of research named the geography of extreme situations is substantiated. The formation of the extreme operating mode in socio-ecological-economic systems (landscapes) that have a destructive, unbalanced nature and lead to imbalances in their development is explored. The term «geography of extreme situations» is introduced to determine the particular area of geographical knowledge, which studies natural and socio-economic phenomena that have the character of fast imbalance. The methodical approaches to investigation of the extremeness level of the territory via the example of Ukraine and the European Union are shown. In geography this approach was applied only to determine the specific features of the influence of natural conditions on human activity. The indicators of environmental disasters that include the amount of pollutant emissions into the atmosphere, the discharge of contaminated sewage into the natural surface water, the degradation of soil resources, the reduction of the forest fund, the species diversity of flora and fauna are disclosed. The different indices of extremeness such as medical and demographic, socioeconomic, engineering, physical-geographical and others are proposed.
Herzinsuffizienzbehandlung in Integrierten Versorgungsmodellen nach § 140 SGB V
Authors: Gysan Detlef Bernd , Pfister Roman , Bansmann Martin , Kalkan Alev , Latz Volker , Scholl Maximilian , Perings Stefan
Published: June 2021

Deutschlandweit werden über 20.000 Patienten in integrierten Herzinsuffizienz-Versorgungsmodellen betreut (Bundesverband Niedergelassener Kardiologen, persönliche Kommunikation, 16. Juli 2020). Durch eine damit einhergehende, leitliniengerechte Pharmakotherapie und regelmäßige Kontrolluntersuchungen lässt sich die Lebensqualität von herzinsuffizienten Patienten deutlich verbessern. Darüber hinaus lassen sich Krankenhauseinweisungen und daraus resultierend Kosten für die Krankenversicherungen minimieren. Eine enge Kooperation (in einem Netzwerk) zwischen Klinikkardiologen, niedergelassenen Kardiologen und Hausärzten ermöglicht eine optimale Herzinsuffizienz-Behandlung in allen Herzinsuffizienz-Schweregraden. Integrierte Versorgungmodelle wie CorBene oder KardioExpert tragen dazu bei, neben einer optimalen Patientenbetreuung, wissenschaftliche Auswertungen vorzunehmen und harte Endpunkte wie Re-Hospitalisierung oder kardiovaskuläre Mortalität zu reduzieren. Das hier
vorgestellte KHAD-Modell (Kölner Herzen Atmen durch") ist ein integriertes Versorgungsmodell in dem die aktuellen Leitlinienempfehlungen zur poststationären Versorgung von Herzinsuffizienzpatienten in der Region Köln umgesetzt werden sollen. Fast allen Krankenkassen unterstützen das Modell. Es nehmen alle Kölner Krankenhäuser und einige der niedergelassenen Kölner Kardiologen teil, um eine optimale Herzinsuffizienz-Versorgung gewährleisten zu können. Solche Modelle für eine Herzinsuffizienz-Betreuung könnten in allen deutschen Großstädten praktiziert werden. Zum Wohle der Patienten, zur Einsparung von Potenzialen bei den Krankenkassen, für eine angemessene Honorierung der behandelnden Ärzte und zur Entlastung der Krankenhäuser – ein Gewinn für unsere Patienten und alle Beteiligten im Gesundheitssystem.
Atriale Tachykardien nach Vorhofflimmerablation: Fluch oder Segen?
Authors: Müller-Edenborn Björn , Jadidi Amir , Arentz Thomas
Published: June 2021

Nach Vorhofflimmerablation kann es neben Vorhofflimmerrezidiven auch zum Auftreten von
verschiedenen atrialen Tachykardien kommen. Obwohl bei atrialen Tachykardien eine regelmäßige
atriale Aktivierung vorliegt, sind diese Rhythmusstörungen für die Patienten häufig stark
symptomatisch und teils kaum medikamentös zu kontrollieren. Für eine individualisierte
Therapieplanung können anhand des Oberflächen-EKGs auch bei vielen vor-abladierten Patienten
rechts- von links-atrialen Tachykardien recht zuverlässig unterschieden werden. Die
Ablationsstrategie richtet sich nach dem Mechanismus der Tachykardie: Auffinden der frühesten
elektrischen Aktivierung und lokale Ablation bei fokalen Tachykardien oder lineare Ablation
zur Unterbindung des Reentry-Kreislaufs bei Makro-Reentry-Tachykardien. Speziell bei Patienten
mit ausgeprägter Vorhoffibrose ist der optimale Therapieansatz aber noch Gegenstand klinischer
Studien.
Katheterablation bei asymptomatischem Vorhofflimmern – Wer profitiert?
Authors: Hindricks Gerhard , Darma Angeliki
Published: June 2021

Die Katheterablation von paroxysmalem oder persistierendem Vorhofflimmern hat sich in den
letzten Jahren als überlegene Therapiebehandlung zur Rhythmusstabilisierung gegenüber
Antiarrhythmika etabliert. Allerdings wird diese Behandlung nach den aktuellen Leitlinien nur
bei symptomatischen Patienten empfohlen. Ein großer Teil der Vorhofflimmerpatienten bleibt
jedoch asymptomatisch. Ältere Studien konnten keinen Vorteil bezüglich der Letalitäts- oder
Apoplexreduktion durch Rhythmusstabilisierung nachweisen. Eine aktuelle randomisierte Studie
zeigt erstmalig eine Reduktion der kardiovaskulären Ereignisse, aber nicht der
Gesamtletalität. Ist nach aktueller Datenlage eine Katheterablation im Falle von
asymptomatischen Patienten berechtigt und wer könnte davon profitieren?
Nicht invasive Vagusstimulation zur Behandlung von paroxysmalem Vorhofflimmern: eine vielversprechende Alternative?
Authors: Steven Daniel , van den Bruck Jan-Hendrik , Wörmann Jonas , Filipovic Karlo , Dittrich Sebastian , Lüker Jakob , Sultan Arian
Published: June 2021

Autonome Dysbalance kann die Wahrscheinlichkeit für das Auftreten von paroxysmalem Vorhofflimmern beeinflussen. Frühere Studien haben gezeigt, dass die Ablation autonomer Ganglien im linken Vorhof Rezidive von Vorhofflimmern reduzieren kann. Die bisherige Therapie von Vorhofflimmern besteht aus wenig effektiven medikamentösen Ansätzen und potenziell mit Risiken behafteten invasiven Verfahren, wie der katheterbasierten Isolation der Pulmonalvenen. Eine einfach durchzuführende nicht invasive Stimulation des N. vagus könnte eine mögliche Therapieoption sein. Die Effektivität dieses Verfahrens ist in einer kürzlich erschienenen randomisierten Arbeit mit einer relativ geringen Anzahl von Patienten untersucht worden. Der vorliegende Artikel gibt einen Überblick über die Therapie und ordnet den Stellenwert perspektivisch ein.
Clinical Efficacy and Safety Profile of Anterior Thalamic Stimulation for Intractable Epilepsy
Authors: Sobstyl Michał , Stapińska-Syniec Angelika , Iwański Szczepan , Rylski Marcin
Published: June 2021

Introduction Deep brain stimulation of the anterior nucleus of the thalamus (ANT DBS) is a neuromodulation therapy for patients with refractory partial seizures. The ANT is the structure of a limbic system with abundant neuronal connections to temporal and frontal brain regions that participate in seizure propagation circuitry.

State of the Art We have performed a literature search regarding the clinical efficacy of ANT DBS. We discuss the surgical technique of the implantation of DBS electrodes with special attention paid to the targeting methods of the ANT. Moreover, we present in detail the clinical efficacy of ANT DBS, with a special emphasis on the stimulation parameters, a stimulation mode, and polarity. We also report all adverse events and present the current limitations of ANT DBS.

Clinical Implications In general, the safety profile of DBS in intractable epilepsy patients is good, with a low rate of surgery, hardware-related, and stimulation-induced adverse events. No significant cognitive declines or worsening of depressive symptoms was noted. At long-term follow-up, the quality-of-life scores have improved. The limitations of ANT DBS studies include a limited number of patients treated and mostly open-label designs with only one double-blind, randomized multicenter trial. Most studies do not report the etiology of intractable epilepsy or they include nonhomogeneous groups of patients affected by intractable epilepsy. There are no guidelines for setting initial stimulation parameters. All the variables mentioned may have a profound impact on the final outcome.

Conclusions ANT DBS appears to be a safe and efficacious treatment, particularly in patients with refractory partial seizures (three-quarters of patients gained at least 50% seizure reduction after 5 years). ANT DBS reduces most effectively the seizures originating in the temporal and frontal lobes. The published results of ANT DBS highlight promise and hope for patients with intractable epilepsy.
A Study of Hormonal Receptors in Esophageal Carcinoma: Northeast Indian Tertiary Cancer Center Study
Authors: Kalita Deepjyoti , Bannoth Srinivas , Purkayastha Joydeep , Talukdar Abhijit , Das Gaurav , Singh Pritesh
Published: June 2021

Background Esophageal cancers, both squamous cell and adenocarcinoma, have poor outcomes with high morbidity and mortality. Our hospital-based registry for the year 2017 to 2018 showed that esophageal cancer constituted 22.7% of annual caseload. Most of our patients present in advanced stages. The aim of this article was to study the role of hormonal receptors in patients with esophageal cancer.

Methods This is a single-institution, prospective, observational study in patients with esophageal carcinoma. Hormonal receptors (estrogen receptor [ER]-α and progesterone receptors) were studied in tumor tissue. Of 160 patients, receptor status was analyzed in 133 patients. Chi-square test was used for the correlation of categorical variables. The value of p < 0.05 was considered as statistically significant.

Results A total of 133 patients was taken into the study of which 96 were males and 37 were females. The mean age of patients was 52 years. Carcinoma esophagus was predominantly seen in males. Estrogen and progesterone receptors were positive in 9.02 and 4.51% of the study population, respectively. Patients with hormonal receptor positivity presented with poor functional status, higher grades of dysphagia, higher stage, and most of the tumors were poorly differentiated with statistically significant p-values.

Conclusion Despite recent advances in various fields of oncology, outcomes of esophageal carcinoma have not improved significantly. Hence, a study of new pathways of pathogenesis in carcinogenesis of esophageal carcinoma is essential. Few recent evidences including our study shows that the hormonal milieu is responsible in the pathogenesis of carcinoma esophagus. The utilization of this data and future study of the role of hormonal therapy might lead to improved outcomes in patients with carcinoma esophagus.
Pure Interstitial 7q21.3-q 31.1 Duplication: A Rare Segmental Genomic Aneuploidy: Case Report and Review of Cases with Distal and Similar Segment Involved
Authors: Di Nora Alessandra , Lena Germana , Giugno Andrea , Di Mari Alessia , Smilari Pierluigi , Minardi Carmelo , Pavone Piero
Published: June 2021

In children with developmental delay (DD) and neurologic impairment, diagnosis can be challenging because of the wide spectrum of causes. Since the last decade, the use of array comparative genomic hybridization (CGH) offered a great contribution to get a diagnosis in complex phenotypes. The chromosome 7 is subject of interest in medical genetics because of its frequent association with chromosome aberrations, rearrangements, and deletions involving clinical manifestations. We hereby reported a 3-year-old male child patient with severe neuro-DD, craniofacial dysmorphisms, and pulmonary stenosis, whose array CGH analysis disclosed a duplication of 14.4 Mb on chromosome 7 (7q21.3-7q31.1). By reviewing the current literature to date, we first reported on neurologic and dysmorphic anomalies related to this rearrangement which was not previously reported.
Management of Acromioclavicular Osteoarthritis in Rotator Cuff Tears: A Scoping Review
Authors: Compagnoni Riccardo , Stoppani Carlo , Menon Alessandra , Cosmelli Nicolò , Fossati Chiara , Ranuccio Francesco , Randelli Pietro
Published: June 2021

Purpose The treatment of acromioclavicular joint (ACJ) osteoarthritis during shoulder arthroscopy is a discussed topic. The aim of this scoping review is to report the current recommendations regarding the management of this disorder in patients undergoing surgery for rotator cuff tears.

Methods A scoping review was performed in Pubmed\Medline and Embase in March 2017, restricted to English language literature. The following keywords were used: (“rotator cuff tear” OR ” rotator cuff” OR “rotator cuff repair”) AND (“acromioclavicular joint arthritis” OR “ac joint arthritis” OR “ac joint” OR “acromioclavicular joint”). Inclusion criteria were randomized controlled trials, prospective cohort studies, retrospective trials, and therapeutic case series. Exclusion criteria were reviews, meta-analyses, and expert opinions.

Results Two retrospective studies and three randomized controlled trials were identified. Clinical studies reported results of 443 shoulders, with an average age of 60.48 years and a mean follow-up of 31.7 months. Many differences were found regarding the design of the studies, patient's selection, surgical procedures, and instrumental and clinical evaluations. No statistically significant differences were found in clinical outcome scores between patients that underwent rotator cuff repair in association with distal clavicular resection and patients with isolated rotator cuff repair.

Conclusion Results of this scoping review underline a lack of evidence-based recommendations about the management of ACJ osteoarthritis in association with arthroscopic rotator cuff repair. Surgical procedures such as distal clavicle resection (DCR) should be performed carefully in this cohort of patients. More prospective randomized studies are needed to reach a consensus about the correct surgical approach to DCR in patients with signs of ACJ osteoarthritis and rotator cuff tears.

Level of Evidence Level III.