bluuebunny/crossref_metadata_2025 huggingface dataset:
Femtosecond laser-assisted creation of anterior capsulorhexis in anterior capsule fibrosis
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, Tambov branch, Tambov, Pirogova E.S. , Fabrikantov O.L. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, Tambov branch, Tambov,   Derzhavin Tambov State University, Medical Institute, Tambov, Nikolashin S.I. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, Tambov branch, Tambov,   Derzhavin Tambov State University, Medical Institute, Tambov
Published: June 2021

Purpose. To optimize the technique for the femtosecond laser-assisted anterior capsulorhexis creation in anterior capsular fibrosis. Material and methods. All patients were divided into two groups: group I included 12 patients with central and peripheral anterior capsule fibrosis who underwent anterior circular capsulorhexis creation using femtosecond laser LensX (Alcon, USA) with laser energy 10 and 15 μJ. Group II included 11 patients with central and peripheral anterior capsule fibrosis who underwent manual capsulorhexis. Results. In group II the operative complications occurred in 3 cases (27.3%), group I was uneventful. Conclusion. Femtosecond laser-assisted anterior capsulorhexis creation in patients with anterior capsule fibrosis allowed reducing the number of operative complications by 27% in comparison with manual capsulorhexis creation. It is advisable to use 10 μJ power to create the anterior capsulorhexis in the area of unaffected and slightly fibrotic anterior capsule cutting the fibrotic part of the anterior capsule by collet scissors. Key words: anterior capsolorhexis, fibrosis, anterior capsule.
Comparative assessment of visual functions and subjective satisfaction of quality of vision in patients with high myopia after implantation of multifocal and phakic intraocular lenses
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Semenova T.K. , Sorokin E.L. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation,   Far Eastern State Medical University, Khabarovsk, Russian Federation
Published: June 2021

Purpose. Comparative analysis of the achieved clinical refraction and the state of visual functions in patients with high myopia after implantation of multifocal and phakic intraocular lenses (IOL), subjective patients satisfaction of the quality of vision when working at close range. Material and methods. The clinical material consisted of 23 patients (46 eyes) with high myopia. 1st group – 10 people (20 eyes), who underwent phacoemulsification with implantation phakic and toric phakic IOLs (IPSL V 2.0) in both eyes, 2nd group – 13 people (26 eyes) – with implantation multifocal and multifocal toric IOLs (Alcon, USA) in both eyes. Uncorrected visual acuity (UCVA) at various distances and subjective patients satisfaction of visual functions using a standard questionnaire were investigated. Results. UCVA indices for the three distances turned out to be comparably high in both groups and did not reveal a statistically significant difference. But for long distance 12 months after the operation, the average UCVA index turned out to be statistically significantly higher in the 2nd group, amounting to 0.65 (0.6; 1) versus 0.5 (0.5; 0.6) in the 1st group. According to the result of the total calculation of the scores of the questionnaire, there was no statistical difference in the obtained indicators; p=0.13. Conclusion. Comparative analysis showed that both methods of IOL implantation in patients with high myopia made it possible to achieve high indicators of visual functions and high satisfaction of quality of vision at any distance. Key words: high myopia, IPCL, phakic IOL, multifocal IOL.
Features of primary IOL implantation in patients with history of chronic uveitis
Authors:   Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuous Professional Education» of the Ministry of Healthcare of the Russian Federation, Sonin D.V. , Kochergin S.A. ,   Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuous Professional Education» of the Ministry of Healthcare of the Russian Federation,   Moscow city ophthalmic center of State Budgetary Institute of Healthcare - City Clinical Hospital named after S.P. Botkin of Moscow Healthcare Department
Published: June 2021

Purpose. To determine possible postoperative complications and methods of their prevention in patients with history of chronic uveitis who underwent Phacoemulsification of cataract with primary IOL implantation. Material and methods. In this article we give clinical analysis of complications after phacoemulsification with primary IOL implantation in patients with history of chronic uveitis. 5 patients with this pathology were hospitalized during 2020. Results. In this work, we provide literature data on the topic of primary IOL implantation in such patients. Currently there is no united opinion on managing such patients. Nevertheless, many authors agree that by using acrylic lenses, prolonged pharmacotherapy, uveitis remission of more than 3 months primary IOL implantation can be safe, and we can get high visual acuity [14]. In hard cases, some authors used primary IOL implantation with primary posterior capsulorhexis, which helped them to lower rate of postoperative complications [2, 3, 11, 21, 24]. Nevertheless, there are cases where IOL cause untreatable uveitis and therefore the question of lens explanation arises [8]. Conclusion. When solving the question of primary IOL implantation during extracting cataract in patients with chronic uveitis for maximum safety we should consider the following: history of the patient's background disease and systemic treatment he is getting, frequency of former uveitic attacks, laboratory data at the time of operation. The patient needs preliminary sanitation of all possible sources of inflammation and infection, pharmacotherapeutical preparation (both topical and general). After operation patient is needed prolonged anti-inflammatory therapy (NAIDS and Corticosteroids) and dynamic observation despite calm eye condition. Key words: uveitis, cataract phacoemulsification, iol implantation.
A Perspective to Stinging Nettles from Emergency Department, Snakebites Worldbite
Authors:   University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Department of Emergency Medicine, Ankara, Turkey, BM Sönmez
Published: June 2021

Venomous snakes are responsible for approximately 1.5-3 million bites as well as perhaps more than 100.0000 fatalities annually worldwide [1]. Although exist 3000 venomous snake species in a global scale, only 200 of them pose a life threat for humans due to venom properties and tooth pattern. The venomous species include Elapidae, Viperidae, Hydrophiidae, Colubridae, and Antractaspididae families [2]. Progressive urban development and degradation of wild life have not resulted in lower rates of attacks of humans by wild animals. On the contrary, animals like snakes pose public health problems due to their venoms [3]. Humans residing in rural environments are reportedly more prone to snakebites than people living in urban centers [4-6]. Such a disparity may result from larger snake populations in rural areas but also people making a living through agriculture, which is reportedly a risk factor for snakebite [7]. People suffering from snakebite are generally adult males actively taking part in professional life [5,8].
Investigating the Factors Having the Important Role in the Standardization of Herbal Distillates’ Methanol Content
Authors:   Departments of Nursing & Midwifery, Rasht Branch of Islamic Azad University, Rasht, Iran, A Rafizadeh , Sh Shariati ,   Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran, MN Safarzadeh Vishekaei ,   Department of Agronomy, Rasht Branch, Islamic Azad University, Rasht, Iran, P Honarchian Masihi ,   Department of pharmacy, Mazandran University of Medical Sciences, Ramsar, Iran, M Rafizadeh ,   Department of pharmacy, Mazandran University of Medical Sciences, Ramsar, Iran
Published: June 2021

Blurred vision leading to nervous blindness is the only symptom of chronic methanol intoxication that occurs following prolonged drinking some kinds of herbal distillates and has been motivated serious anxieties. The methanol content of these products is not usually measured which may be due to the lack of applicable standards in this regard. In this study, the methanol concentrations of some kinds of herbal distillates were quantified by two different methods to define the most effective factors in the determination of methanol permitted dose of these products. In this study, the methanol contents of 60 different samples were examined by a newly designed kit and Gas Chromatography methods, and finally, based on gained results some recommendations were presented about how standardization of herbal distillates’ methanol content. All samples have different concentrations of methanol that in some cases, their methanol content seems enough for the creation of chronic methanol intoxication. Also, access to an appropriate and efficient national standard for controlling of methanol content of herbal distillates seems to be necessary.
Identification of Novel GSK-3β Inhibitors through Docking Based Virtual Screening and Biological Evaluation
Authors:   Zhejiang University of Technology, State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China, M Xu , SY Gao ,   Zhejiang University of Technology, State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China, YX Zeng ,   Zhejiang University of Technology, State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China, JR Gao ,   Zhejiang University of Technology, State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China, Q Ye ,   Zhejiang University of Technology, State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China, G Cheng ,   Zhejiang Chinese Medicinal University, College of Pharmaceutical Sciences, China, L Xu ,   National Center for Drug Screening, State Key Laboratory of Drug Research, Chinese Academy of Sciences, China, J Li ,   National Center for Drug Screening, State Key Laboratory of Drug Research, Chinese Academy of Sciences, China, YB Zhou ,   National Center for Drug Screening, State Key Laboratory of Drug Research, Chinese Academy of Sciences, China
Published: June 2021

GSK-3β is a key regulator in insulin, Wnt and NF-κB signaling pathways. Dysregulation of GSK-3β is often related to tumors and diabetes. Inhibiting it might provide cure for diabetes, tumors, neurodegeneration and brain ischemia. Although there are a number of reported GSK-3β inhibitors, the scaffold is limited. Herein we report a discriminatory analysis-based molecular docking on the Specs database, and identiﬁed 3 novel GSK-3β inhibitors with moderate IC50 (ranging from 17.42 μM to 6.74 μM) in the following in vitro biological test. Further dynamic simulations and docking pose analysis were performed to give a better understanding on the binding conformation of 3 hit compounds AK- 777/09836064, AK-968/37185006 and AN-698/41607072, which would provide basis for further optimization.
Straight Back Syndrome with Heart Failure and Myocardial Injury Diagnosis by Cardiac Magnetic Resonance
Authors:   Department of Radiology, The First Hospital of Lanzhou University, Lanzhou, 730000, People’s Republic of China, Z Chen , C Lin ,   Department of Radiology, The First Hospital of Lanzhou University, Lanzhou, 730000, People’s Republic of China, J Nan ,   Department of Radiology, The First Hospital of Lanzhou University, Lanzhou, 730000, People’s Republic of China, X Zhuang ,   Department of Radiology, The First Hospital of Lanzhou University, Lanzhou, 730000, People’s Republic of China, J Lei ,   Department of Radiology, The First Hospital of Lanzhou University, Lanzhou, 730000, People’s Republic of China, S Guo ,   Department of Radiology, The First Hospital of Lanzhou University, Lanzhou, 730000, People’s Republic of China, J Xue ,   Department of Radiology, The First Hospital of Lanzhou University, Lanzhou, 730000, People’s Republic of China, B Han ,   Department of Cardiology, The First Hospital of Lanzhou University, Lanzhou, People’s Republic of China, Z Zhang ,   Department of Cardiology, The First Hospital of Lanzhou University, Lanzhou, People’s Republic of China, M Lu ,   Department of Magnetic Resonance Imaging, Cardiovascular Imaging and Intervention Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China, S Zhao ,   Department of Magnetic Resonance Imaging, Cardiovascular Imaging and Intervention Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China
Published: June 2021

Straight Back Syndrome (SBS) is an autosomal dominant hereditary disease characterized by abnormal thoracic skeletal dysplasia, which leads to a decrease in anteroposterior diameter of the thorax and thereby the heart and great vessels are compressed and displaced. We reported a case with SBS showing cardiac dysfunction and myocardial injury by CMR. This case should remind physicians of the importance of differential diagnosis in patients with heart failure and arrhythmia.
Another Brick in the Wall of an Ongoing Discussion– Reduction of Anastomotic Leaks after Colorectal Resection by Preoperative Mechanical Bowel Preparation in Combination with Oral and Parenteral Antibiotics?–A Clinical Retrospective Single Center Study
Authors:   Department of General-Visceral and Minimally Invasive Surgery, O Safia ,   KRH Siloah, Academic Teaching Hospital of the Hannover Medical School, Germany, S Kuebler ,   Department of General-Visceral and Minimally Invasive Surgery; KRH Siloah, Academic Teaching Hospital of the Hannover Medical School, Germany, JW Mall ,   Department of General-Visceral and Minimally Invasive Surgery; KRH Siloah, Academic Teaching Hospital of the Hannover Medical School, Germany, SR Tallbot ,   Department of Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, Germany
Published: June 2021

Background: In colorectal surgery, postoperative Anastomotic Leak (AL) is a serious complication. Besides the surgeon`s experience, bowel preparation may have an impact on AL, but the published data are still inconclusive. The purpose of this retrospective single center study was to investigate the role of preoperative Mechanical Bowel Preparation (MBP) in combination with Oral Antibiotic Bowel Preparation (OBP) and parenteral antibiotics in a certified highvolume colorectal center. Methods: In the period of January 2017 to December 2019, all colon and rectal surgeries were recorded and separated into emergency and elective surgeries. Patients in the elective surgery group were further divided into two groups: patients with Bowel Preparation (BP) and patients without BP and were evaluated concerning to AL, postoperative hospital length of stay and mortality. Results: Between 2017 to 2019, 625 patients underwent colorectal surgery. 262 patients had emergency operations and were therefore excluded from the study. 363 patients underwent colorectal elective surgery (197men, 166 women). 44.0% received Combined Bowel Preparation (CBP), 46.8% received no BP, 3.3% received OBP only, 4.1% received MBP only, and for 1.1% nothing was documented. CBP was not only associated with a reduction in the rate of AL (P=0.038) (14.1% vs. 4.4%), but also with reduction in mortality (P=0.032) (7.6% vs. 1.2%) and length of stay (P=0.016) (14 vs. 11 days). Conclusion: Our retrospective data showed a significant impact of preoperative intestinal preparation with MBP in combination with OBP and parenteral antibiotics on AL, length of stay and mortality. Therefore we strongly recommend the use of this regimen of preoperative BP in elective colorectal surgery.
Antepartum COVID-19 and Postpartum Autism
Authors:   Department of Obstetrics & Gynecology, Hebrew University-Hadassah Hospital, Israel, G Steinman , D Mankuta ,   Department of Obstetrics & Gynecology, Hebrew University-Hadassah Hospital, Israel
Published: June 2021

A little over a year ago, a new viral disease appeared worldwide. Much like earlier pathologic RNA viruses, Covid-19 can cause distinctive harmful effects on pregnant women and their offspring. Because of the coexistent fever associated with a rise in pro-inflammatory interleukins in the most severe cases, there is a serious concern about the baby’s neurologic development. Although not yet observed in many Covid-19 pregnancies, it is anticipated particularly that the onset of autism in the child may be realized in a year or more postpartum. Prior studies have reported that exclusive breast-feeding which provides a good source of IGF1 for the baby may well reduce the incidence of autism in such cases.
Tachicardia-induced cardiomyopathy. Case report
Authors: Atabegashvili Maria R. , Shchekochikhin Dmitry Yu. , Gromyko Grigory A. , Pershina Ekaterina S. , Bogdanova Alexandra A. , Nesterov Alexey P. , Shilova Alexandra S. , Gilyarov Mihail Yu. , Svet Alexey V.
Published: June 2021

The tachycardia-induced cardiomyopathy is a rare case of reversible heart failure and left ventricle disfunction. The diagnostic approach and treatment strategy are described in this article. Also the clinical case of heart failure compensation in the patient with left ventricle dilatation and atrial flutter after the reverse to sinus rhythm is after catheter ablation presented.
Extraesophageal signs of gastroesophageal reflux disease: otorhinolaryngologist’s view
Authors: Radtsig Elena Yu. , Konstantinov Daniil I.
Published: June 2021

The data on association between various pathologies of the ENT organs and gastroesophageal reflux disease (GERD) is analysed in the article. The variety of extraesophageal signs of GERD in children and adults is given, what is advisable to inform physicians of different specialties about the possibilities of antireflux therapy. These options are expanded with the emergence of a unique new drug, Alfasoxx. Its bioadhesive formula is based on hyaluronic acid and chondroitin sulphate thereby protecting the esophageal mucosa. Alfasoxx acts on the surface of the esophageal mucosa without penetrating into the systemic bloodstream and it also has a low allergenic potential, which has been confirmed by numerous studies. With its healing and repairing effect on erosive lesions of the esophageal epithelium, Alfasoxx in combination with proton pump inhibitors is more effective in achieving regression of clinical manifestations of the disease and improving patients quality of life (according to SF-36 questionnaire) compared to proton pump inhibitors monotherapy.
The relationship between obesity, cardiometabolic disorders and disease activity in psoriatic arthritis patients: data from the Russian register
Authors: Korsakova Yuliia L. , Korotaeva Tatiana V. , Loginova Elena I. , Gubar Elena E. , Vasilenko Elizaveta A. , Vasilenko Aleksei A. , Kuznetsova Natalia A. , Patrikeeva Irina M. , Nasonov Evgeny L.
Published: June 2021

Aim. To study the relationship between obesity, cardiometabolic disorders and disease activity in patients with psoriatic arthritis (PsA) in real practice.
Materials and methods. The Russian register included 614 PsA patients [female 331 (54%)/283 (46%)]. Average age 45.20.52 years, PsA duration 5.70.27 years, psoriasis 15.710.56 years. Patients underwent examination, body mass index (BMI), PsA activity according to DAPSA, cDAPSA, analysis of concomitant diseases were assessed. The patients were divided into 3 groups depending on BMI (kg/m2): normal 25 (group 1), increased 2530 (group 2), obesity 30 (group 3).
Results. The average BMI was 27.70.23 kg/m2, normal BMI in 213 (34.7%), increased in 214 (34.8%) and obesity in 187 (30.5%). Concomitant diseases in 297 (48%). In group 3, arterial hypertension was observed significantly more often than in groups 1 and 2 (p0.0001); more often than in group 2 diabetes mellitus (p0.0001), metabolic syndrome (p0.0001); more often than in group 1 ischemic heart disease (p=0.026). PsA activity at Baseline, after 6/12 months was significantly higher in group 3 (p0.031). In obese patients, the chance of a decrease in disease activity to a moderate/low level and remission during therapy for 6/12 months is 2.484 times lower than in group 1, and 2.346 times lower than in group 2: odds ratio 2.346 (95% сonfidence interval 1.075.143) and 2.484 (95% сonfidence interval 1.1355.439), respectively.
Conclusion. In the majority (65.3%) of PsA patients, BMI exceeded the norm. Obesity is associated with a high incidence of cardiometabolic disorders, with higher PsA activity and lower treatment efficacy.
Vitamin D status in women with rheumatoid arthritis: frequency of hypovitaminosis, associations with disease activity, body composition and comorbidity
Authors: Dobrovolskaya Olga V. , Toroptsova Natalia V. , Nikitinskaya Oksana A. , Samarkina Elena Y. , Cherkasova Mariia V. , Feklistov Aleksei Y.
Published: June 2021

Aim. To evaluate the status of vitamin D in women with rheumatoid arthritis (RA) and establish its associations with comorbidity, disease activity, and body composition components.
Materials and methods. 86 women with RA (average age 58.18.5 years) were enrolled in the study. We analyzed the relationship of vitamin D levels with clinical and laboratory parameters and with the results of two-energy x-ray absorptiometry. MannWhitney or KruskalWallis, 2 and Spearman tests were performed using Statistica for Windows 10.0 (StatSoft Inc., USA).
Results. Vitamin D level was 22.4 [17.8; 27.3] ng/ml: deficiency was detected in 33%, and insufficiency in 46% of women with RA. Only 41% of patients with low vitamin D levels received supplements of cholecalciferol, while only 9% in a sufficient dose. 25(OH)D level was significantly lower in RA patients with sarcopenia, obesity, high activity according to DAS28 and in those who did not receive vitamin D supplements. There werent differences in 25(OH)D levels among subgroups of patient according to age, fertility, BMD status, comorbidity index, RA duration, ESR and CRP levels, medical therapy performed.
Conclusion. 79% of patients with RA had low levels of vitamin D, while less than half of them received additional cholecalciferol supplements. Low vitamin D levels in RA patients were associated with high disease activity, sarcopenia, and obesity.
Modern approaches to immunization of patients of rheumatologic profile
Authors: Belov Boris S. , Tarasova Galina M. , Muravyeva Natalia V.
Published: June 2021

Recently, the importance of comorbid infections in rheumatology has increased significantly, which have a significant impact on morbidity and mortality, especially in immuno-inflammatory rheumatic diseases (IIRD). In this regard, vaccination is becoming increasingly important in the prevention of infections in these patients. This review presents an updated version of the recommendations for vaccination of adult patients with IIRD, prepared by experts of the European Union League against Rheumatism (EULAR). There is a low (suboptimal) vaccination coverage of these patients, partly due to the low frequency of referral by doctors. The role of the rheumatology team in solving the problems associated with immunization of patients with IIRD is emphasized, as well as the importance of joint decision-making taking into account the needs and preferences of patients. The issues concerning the use of vaccines against influenza, pneumococcal infection, hepatitis B,
Consent. Modern interpretation: "Voluntary Informed Consent"
Authors: Chuchalin Alexandr G.
Published: June 2021

The article is devoted to voluntary informed consent. It considers the historical issues of the formation of this concept in modern health care and medical science. The article highlights a historical role of the Nuremberg Code which was taken as the basis for the Universal Declaration of Human Rights, the World Medical Association (WMA) Code of Ethics, the Declaration on Bioethics and Human Rights, i.e. documents that defined the world order after the end of World War II.
Cerebral edema: from the origins of the description to the modern understanding of the process
Authors:   Pirogov Russian National Research Medical University, Moscow, Russia, Gudkova Valentina V. , Kimelfeld Ekaterina I. ,   Pirogov Russian National Research Medical University, Moscow, Russia, Belov Stanislav E. ,   Hospital for War Veterans №3, Moscow, Russia, Koltsova Evgeniia A. ,   Pirogov Russian National Research Medical University, Moscow, Russia, Stakhovskaya Ludmila V. ,   Pirogov Russian National Research Medical University, Moscow, Russia
Published: June 2021

The article, which is a review-lecture, reflects the historical milestones in the description and study of cerebral edema (CE) from ancient times to the present. Great attention is paid to the Monroe–Kellie doctrine, without which it is impossible to understand the mechanism of development of a vitally significant complication of CE – intracranial hypertension. The importance of the Monroe–Kellie doctrine in substantiating the symptomatic treatment of increased intracranial pressure is emphasized. The possible involvement of the glymphatic system in both the decrease and the increase in increased intracranial pressure is discussed. The modern ideas about the blood-brain barrier (BBB), its role in the development of CE and an increase in intracranial volume are analyzed. With the study of the molecular mechanisms of BBB damage and the development of targeted therapy, the researchers associate future advances in the treatment of CE. The great interest of modern authors in the state of the BBB in various diseases, as well as in the violation of its integrity in COVID-19 is reflected. It is noted that the main and only, today, method for diagnosing CE is neuroimaging. Development has begun on the isolation of potential biochemical markers of CE from blood.
Strategies to enhance the treatment of lacunar stroke
Authors:   Research Center of Neurology, Moscow, Russia, Maksimova Marina Yu. , Airapetova Aleksandra S. ,   Research Center of Neurology, Moscow, Russia
Published: June 2021

Lacunar stroke (LS) is caused mainly by pathological changes in the small intracerebral (perforating) arteries, which are typical for arterial hypertension primarily. The current review highlights actual treatment strategies to LS. The management of patients with LS is carried out in accordance with the general approaches for ischemic stroke treatment and includes acute reperfusion and prevention of recurrent stroke. The choice of antithrombotic therapy in patients with LS is based on assessment of intracerebral hemorrhage and systemic bleeding risks. Dual antiplatelet therapy in patients with LS is not provide a significant benefit beyond aspirin monotherapy, increasing intracerebral hemorrhage risk.
Refeeding syndrome and its prevention in patients with anorexia nervosa
Authors:   Dzhanelidze Saint Petersburg Research Institute of Emergency Medicine, Saint Petersburg, Russia, Luft Valerii M. , Tyavokina Elena Iu. ,   Dzhanelidze Saint Petersburg Research Institute of Emergency Medicine, Saint Petersburg, Russia, Sergeeva Anastasiia M. ,   Dzhanelidze Saint Petersburg Research Institute of Emergency Medicine, Saint Petersburg, Russia, Lapitsky Aleksei V. ,   Dzhanelidze Saint Petersburg Research Institute of Emergency Medicine, Saint Petersburg, Russia
Published: June 2021

Aim. To study the condition of the problem, the prevalence and severity of dyselectrolytemia, as a possible manifestation of the syndrome of renewal of nutrition (refeeding syndrome) in patients with anorexia nervosa (AN). Materials and methods. We studied somatometric indicators and the prevalence of electrolyte disturbances of 81 women aged from 18 to 55 years, who were treated in the somato-psychiatric department of the Dzhanelidze Saint Petersburg Research Institute of Emergency Medicine. Results. Hypotrophy predominates as marasmus (95.2%) in the early stages of AN. At the later stages of development of AN, the frequency of mixed hypotrophy by the type of marasmatic kwashiorkor increases significantly (up to 63.2%), which is manifested by a decrease not only in somatometric indices, but also in depletion of the visceral protein pool. When studying the frequency of electrolyte disturbances, hypokalemia was most often observed in patients with NA in the initial period of realimentation (14.8%). At the same time, its moderately expressed degree prevailed. Moderate hypophosphatemia (not less than 0.6 mmol/L), which may indicate a latent manifestation of refeeding syndrome, was relatively often (21.1%) observed in patients with severe malnutrition (body mass index less 12.5 kg/m²). Hypomagnesemia for the entire period of observation of patients with various stages of the disease were not detected. Conclusion. Diselectrolytemia is often observed in patients with AN during their refeeding, which requires regular dynamic monitoring of serum potassium, magnesium and phosphate levels and timely correction of their deficiency.
TOROPETSKY UEZD IN THE MIDDLE AGES IN RUSSIAN HISTORIOGRAPHY: FACTORS OF FORMATION OF TERRITORIAL-ADMINISTRATIVE DIVISION AND SETTLEMENT
Authors: Карпова Мария Владимировна , Степанова Юлия Владимировна
Published: June 2021

Статья посвящена особенностям формирования территориально-административной структуры территории Торопецкого уезда в трудах отечественных историков. Пристальное внимание обращено на развитие Торопца в период его вхождения в состав Великого княжества Литовского. В этот период продолжали развиваться тенденции - налоговые, политические и промысловые - древнерусского периода. Среди факторов, оказавших влияние на формирование территориально-административного деления и поселенческой структуры, выделены периферийное положение Торопца, его статус господарского населенного пункта, прямой сбор налогов и одновременно сохранение относительной самостоятельности, что вызвало споры в отечественной историографии. В историографии отмечается также вовлеченность населения в промысловую деятельность, что повлияло на формирование особых территорий - перевар - в Торопецком уезде. Выявлена также специфическая организация поселенческой структуры в виде гнезд поселений.

The article is devoted to the characteristic of the formation of the territorial-administrative structure of the territory of Toropetsky uezd in Russian historiography. Much attention is given to the development of Toropets as a part of Lithuania, it was continuing to develop the taxing, political and working tendencies of ancient Russia. Among the factors that have influenced on the formation of the territorial-administrative division and settlement structure, there are the boundary position of Toropets, its status as a Grand Duke’s settlement, direct tax collection and at the same time the preservation of relative independence, which caused controversy in Russian historiography. In historiography there is also the engagement of people in forest bee-keeping that have influenced on the formation of special territories - perevaras - in Toropetsky uezd. The specific organization of the settlement structure in the form of settlement nests is also revealed.
Referensi dalam Kumpulan Cerpen Turun Ranjang Menjaring Angin Karya Hatmiati Masy’ud
Authors: Jahdiah NFN
Published: June 2021

Abstrak:Pengacuan  atau referensi adalah salah satu jenis kohesi gramatikal yang berupa satuan lingual tertentu yang mengacu pada satuan lingual lain yang mendahului atau mengikutinya. Masalah yang dibahas dalam penelitian ini adalah apa saja referensi yang terdapat dalam  kumpulan cerpen Turun Ranjang Menjaring Angin Karya Hatmiati. Penelitian ini bertujuan  a) mendeskripsikan referensi persona dalam kumpulan cerpen Turun Ranjang Menjaring Angin Karya Hatmiat Masy’ud, b) Mendeskripsikan  referensi demostratif Kumpulan Cerpen Turun Ranjang Menjaring Angin Karya Hatmiat Masy’ud, c) Kumpulan Cerpen Turun Ranjang Menjaring Angin Karya Hatmiat Masy’ud. Metode penelitian yang digunakan dalam penelitian ini adalah deskriptif dengan  pendekatan kualitatif. Dalam analisis data dilakukan penelaahan juga dilakukan metode agih, yaitu metode yang pelaksanaannya dengan menggunakan unsur bahasa itu sendiri. Teori yang digunakan dalam penelitian ini adalah teori analisis wacana yang dikemukan oleh Haliday dan Hasan. Hasil kajian ini menunjukan bahwa dalam kumpulan Cerpen Turun Ranjang Menjaring Angin terdapat ada tiga referensi yaitu a) referensi persona,  diantaranya  kamu, saya, aku, kita, dia, dan –mu. b) referensi demostratif diantaranya  kedai, pingir kota, jembatan, malam, subuh, Jakarta, Balangan, di sini, Telaga Silaba, Amuntai, Bandara Syamsuddinoor. 3) Referensi  kompratif diantaranya seperti, laksana.
Depoimentos, Memórias, Hugo Rodas.
Authors: Iara Pietricovsky Valéria Cabral e
Published: June 2021

Companheiras de longa data de Hugo Rodas, Valéria Cabral e Iara Pietricovsky trazem lembranças de sua convivência com o querido amigo, na celebração de seus 80 anos.
O Teatro: um duplo artístico ”“ tragédia e comédia em Acarnenses, de Aristófanes e no Auto da Compadecida de Ariano Suassuna
Authors: Jacson Martins Vieira Francisco
Published: June 2021

Por ser uma arte que permanece há tantos séculos, o teatro desperta curiosidade acerca de seus primórdios, existindo várias conjecturas e teorias sobre o surgimento da Comédia Antiga como ambiente extremamente propício à formação de duplos, a partir de uma série de elementos presente no mito e culto do deus do teatro, Dioniso, no qual as vozes, os gestos e as máscaras são sobrepostas, como causa de equívocos e componentes centrais das invectivas pessoais ou intrigas, transformando-se em acessórios fundamentais para o discurso moralizante e para alcançar o objetivo maior do a(u)tor: a obtenção da paz em Acarnenses, de Aristófanes, e a absolvição no Auto da Compadecida, de Ariano Suassuna.
A Cidade e o Teatro em Cavaleiros de Aristófanes: O Poeta e o Político ”“ Introdução Ã tradução de Cavaleiros.
Authors: César Pompeu Ana Maria
Published: June 2021

A peça Cavaleiros, de Aristófanes, data de 424 a.C. e é a comédia mais política dentre as que nos restaram do comediógrafo, logo também é a mais política da comédia antiga grega. O enredo da peça é uma disputa, ou agón, entre um escravo (o Barraqueiro, que representa o demagogo Cléon), recém-comprado pelo Povo, personificado como o patrão, e um vendedor de chouriços (o Vendetripa, que sugerimos representar o Poeta coÌ‚mico), pela liderança de Atenas. A rivalidade e o antagonismo entre o Vendetripa e o Barraqueiro escondem uma identidade e duplicação de um no outro. O Povo de Atenas é a presa disputada por ambos, que usam de impudência e de malícia para conseguir o governo da pólis. Mas, no final, o Vendetripa se revela amigo verdadeiro do Povo, enquanto o Barraqueiro apenas finge ter amor ao Povo, para enriquecer. Traduzimos os nomes das personagens enfatizando suas características de vendedores do mercado: Vendetripa, Barraqueiro, Bom de Feira, Zeus Feirante.
Jean-Jacques Lemêtre e a escuta do inaudível: princípios e procedimentos que permeiam suas atividades dentro e fora do Théâtre du Soleil
Authors: Amalfi Marcello
Published: June 2021

Este artigo visa oferecer um panorama sucinto de alguns dos princípios e procedimentos que orientam a atuação de Jean-Jacques Lemêtre enquanto músico do Théâtre du Soleil, e que estão igualmente presentes em sua atuação conduzindo estágios e workshops de música do teatro. Além de trechos de entrevistas exclusivas e inéditas de membros e pessoas ligadas à companhia, traz um pequeno glossário com alguns dos termos cunhados sobre tal atuação no decorrer de nossa pesquisa de Doutorado em Artes na Universidade de São Paulo, com estágio doutoral na Sorbonne Nouvelle Université Paris 8.
A encenação de ópera em busca do gesto icástico
Authors: Proença Guilherme
Published: June 2021

A presente reflexão procura clarificar o processo teórico e prático da encenação do gesto na representação lírica e a sua importá‚ncia para a criação global da imagem cénica. O gesto icástico é uma “singularidade” visual, verbal ou musical, destinada a comunicar o mais claramente possível uma intenção, um sentimento ou um significado. Ele é também ingrediente fundamental na articulação e equilíbrio de todos os signos interartísticos evoluindo no espaço tempo do espetáculo.
Peças de Ocasião: Cenas E(m) Música III
Authors: Mota Marcus
Published: June 2021

Reunião de partituras elaboradas a partir de contextos diversos, mas com uma coisa em comum: estabelecer relações entre sons e referentes extra-musicais. Entre as obras temos, Music of No Changes V, Odd Funk,Waiting for You, FIboNUts, Baião, Tertian Piano.
Apresentação: Música da Antiguidade e do Medievo: Performance, recepção e recriação
Authors: Vergara Cerqueira Fábio
Published: June 2021

Apresentação dossiê  Música da Antiguidade e do Medievo: Performance, recepção e recriação
A performance nas cantigas galego-portuguesas: desafios entre oralidade e tradição manuscrita trovadoresca
Authors: Ferreira de Paula Pessoa Felipe
Published: June 2021

Apesar do significativo aumento de interesse do público pela Idade Média, a música da lírica medieval galego-portuguesa ainda representa um grande desafio de interpretação e recriação. Motivados por essa questão, propomos neste artigo uma reflexão sobre a performance das cantigas galego-portuguesas, reconhecendo suas especificidades enquanto canção em um meio de criação e transmissão oral. Para tanto, analisaremos as perspectivas e métodos propostos pela musicologia e pelo movimento da Música Antiga ”“ Early Music ”“ para as fontes medievais e os principais desafios diante do escasso material oferecido pelos pergaminhos Vindel e Sharrer, fragmentos que contêm cantigas de amigo e de amor, respectivamente, com notação musical. Consideramos que o conceito de performance e sua compreensão no contexto medieval é fundamental para avançar- mos na interpretação da performance trovadoresca, cujas próprias cantigas propiciam alguns indícios, que pretendemos explorar neste artigo.
Experimentos com poesia e performance: um ensaio no (e com o) ensino da poesia grega antiga
Authors: Bacelar Agatha
Published: June 2021

O projeto de iniciação cientifica (PIBIC) “Entre festas e ritmos: aspectos performativos e musicais da poesia grega antiga” foi concebido para acolher estudantes no desenvolvimento de estudos de caso sobre poemas específicos. Cada plano de trabalho deve realizar um estudo introdutório sobre o contexto performativo do poema em questão e, em um segundo momento, incentivar experimentos de vocalização e percussão com o poema. Esses experimentos, adaptados de jogos de improviso vocal e de percussão corporal, são então propostos em oficinas de extensão abertas ao público não especializado. Este texto apresenta os estudos de caso desenvolvidos por dois estudantes entre 2018 e 2019 e faz um relato da primeira edição da oficina, realizada em 2019.
Sobre a composição musical Marsias contra Apolo: uma associação entre composição musical contemporá‚nea e mitologia grega
Authors: Perdigão Thiago
Published: June 2021

O presente artigo tem por objetivo expor e analisar o contexto mitológico da composição musical Marsias contra Apolo, para flauta solo, em sua relação com as técnicas e elementos musicais utilizados em sua composição. Assim, procuraremos expor primeiramente o mito grego que envolve o cerne da composição, depois a relação deste mito com os elementos musicais mais essenciais, e, por fim, como tais elementos foram então desenvolvidos.
Suíte Clássica. Para vozes e instrumentos (2020)
Authors: Mota Marcus
Published: June 2021

As partituras completas da Suíte Clássica. Para vozes e Instrumentos são disponibilizadas.
Fotojornalismo como fonte histórica
Authors: Ribeiro dos Santos Eunice
Published: June 2021

O presente artigo visa fazer uma revisão das principais ideias de Ernest Gombrich, Roland Barthes, e Eliseo Verón a respeito da análise de imagens a fim de averiguar quais as contribuições que os mesmos podem dar ao historiador no trabalho com jornais e revistas antigos, ou seja, suportes impressos como fontes históricas.
Impactos da pandemia da COVID-19 na dispensação de medicamentos pela assistência farmacêutica da regional de Pirapora
Authors: Gonçalves Pereira Giovana , Bahia Felicíssimo Zocratto Keli , De Oliveira Patrícia , Soares Santos André
Published: June 2021

A pandemia da Covid-19 tem exigido do poder público a adoção de medidas sanitárias emergenciais, visando diminuir o contágio e preservar a saúde da população. Essas medidas demandam a participação de todo sistema de saúde em seus diferentes níveis (municipal, estadual e federal), uma vez que várias mudanças regulatórias afetam a dispensação de medicamentos e o funcionamento das farmácias. Nessa perspectiva, o presente artigo tem por objetivo descrever as medidas de flexibilização e adequação adotadas pela Coordenação da Assistência Farmacêutica (CAF) da Gerência Regional de Saúde de Pirapora, durante a pandemia causada pela Covid-19, com base nas legislações do Ministério da Saúde, Secretaria de Estado da Saúde de Minas Gerais e da Agência Nacional de Vigilância Sanitária (Anvisa). Trata-se de um estudo de caso, de caráter descritivo com abordagem qualitativa e análise documental. Os resultados mostram que as medidas emergenciais adotadas subsidiaram a reorganização dos processos de serviços da CAF da Gerência Regional de Pirapora, no sentido de minimizar a aglomeração e exposição dos usuários, promover o distanciamento social e medidas de higiene dentro das farmácias, contribuindo para a redução do risco de disseminação e contágio do vírus causador da Covid-19 entre os usuários e servidores.
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Produção pública de medicamentos no Brasil no contexto da pandemia da COVID-19
Authors: Teixeira Pinto Ferreira Neto Paula , Rocha da Cunha Camila
Published: June 2021

No Brasil, o Sistema Único de Saúde foi instituído nas bases da Constituição Federal de 1988, que estabeleceu, dentre outros campos de atuação, a sua participação na produção de medicamentos e na promoção do desenvolvimento científico e tecnológico e a inovação em saúde. Este ensaio discute a produção pública de medicamentos no âmbito dos laboratórios oficiais e seus desafios no contexto da pandemia de COVID-19, utilizando-se como base os medicamentos do estudo Solidarity. O Brasil conta com 20 laboratórios oficiais que juntos possuem 289 medicamentos aprovados, compostos por 169 fármacos, em diferentes apresentações, além de 86 Parcerias para o Desenvolvimento Produtivo vigentes que envolvem o desenvolvimento e transferência de tecnologias de outros 55 medicamentos. Nos últimos anos, diversas políticas desenvolvidas no Brasil promoveram o desenvolvimento e a produção de medicamentos estratégicos para a população, reduzindo a dependência produtiva e tecnológica e contribuindo para a diminuição da vulnerabilidade do SUS. Contudo, desafios como a deficiência de infraestrutura e de competências técnicas e gerenciais dos laboratórios públicos, dependência externa de insumos farmacêuticos e políticas recentes de austeridade fiscal, fragilizam o País para o enfrentamento da pandemia.
Education Reforms for Equity and Quality: An Analysis from an Educational Ecosystem Perspective with Reference to Finnish Educational Transformations
Authors: Niemi Hannele
Published: June 2021

The article starts with the serious question of why educational reforms do not lead to better learning. Although access to education has increased remarkably, the quality of education can be very low. The reality is that by 2030 there will be 800 million young people who do not have basic skills in reading and math. The answers will be sought from the concept of the educational ecosystem and how different subsystems, such as curriculum system, evaluation systems, teacher education policy, and the labour market, should be interconnected, and the systemic changes supported by all these subsystems. The basic conditions are that different actors and stakeholders work in collaboration, there are active interactions within and between different subsystems for supporting both equity and quality in education. Educational reforms are complex processes and need diverse partners and governance in which trust is present. The article also provides a brief case description in Finnish contexts of how educational reforms have been implemented in the frame of the ecosystem concept. In the end, the article summarises how educational ecosystems could help in overcoming global learning crises.
GLOBALIZATION EFFECTS ON CONTAGION RISKS IN FINANCIAL MARKETS
Authors: Paskaleva Mariya , Stoykova Ani
Published: June 2021

Financial globalization has opened international capital markets to investors and companies worldwide. However, the global financial crisis also caused massive stock price volatility due in part to global availability of market information. We explore ten EU member states (France, Germany, the United Kingdom, Belgium, Bulgaria, Romania, Greece, Portugal, Ireland, and Spain), and the USA. The explored period is March 3, 2003 to June 30, 2016, and includes the effects of the global financial crisis of 2008. The purpose of the article is to determine whether there is a contagion effect between the Bulgarian stock market and the other examined stock markets during the crisis period and whether these markets are efficient. We apply an augmented Dickey-Fuller test, DCC-GARCH model, autoregressive (AR) models, TGARCH model, and descriptive statistics. Our results show that a contagion between the Bulgarian capital market and the eight capital markets examined did exist during the global financial crisis of 2008. We register the strongest contagion effects from the U.S. and German capital markets on the Bulgarian capital market. The Bulgarian capital market is relatively integrated with the stock markets of Germany and the United State, which serves as an explanation of why the Bulgarian capital market was exposed to financial contagion effects from the U.S. capital market and the capital markets of EU member states during the crisis. We register statistically significant AR (1) for UK, Greece, Ireland, Portugal, Romania, and Bulgaria, and we can define these global capital markets as inefficient.