bluuebunny/crossref_metadata_2025 huggingface dataset:
A TNFR2–hnRNPK Axis Promotes Primary Liver Cancer Development via Activation of YAP Signaling in Hepatic Progenitor Cells
Authors: Meng Yan , Zhao Qiudong , An Liwei , Jiao Shi , Li Rong , Sang Yan , Liao Jianping , Nie Pingping , Wen Fuping , Ju Junyi , Zhou Zhaocai , Wei Lixin
Published: February 2021

Most primary liver cancer (PLC) cases progress mainly due to underlying chronic liver inflammation, yet the underlying mechanisms of inflammation-mediated PLC remain unclear. Here we uncover a TNF receptor II (TNFR2)–hnRNPK–YAP signaling axis in hepatic progenitor cells (HPC) essential for PLC development. TNFR2, but not TNF receptor I (TNFR1), was required for TNFα-induced activation of YAP during malignant transformation of HPCs and liver tumorigenesis. Mechanistically, heterogeneous nuclear ribonuclear protein K (hnRNPK) acted downstream of TNFα–TNFR2 signaling to directly interact with and stabilize YAP on target gene promoters genome-wide, therefore coregulating the expression of YAP target genes. Single-cell RNA sequencing confirmed the association of TNFR2–hnRNPK with YAP expression and the pathologic importance of HPC. Accordingly, expressions of TNFR2, hnRNPK, and YAP were all upregulated in PLC tissues and were strongly associated with poor prognosis of PLC including patient survival. Collectively, this study clarifies the differential roles of TNFRs in HPC-mediated tumorigenesis, uncovering a TNFR2–hnRNPK–centered mechanistic link between the TNFα-mediated inflammatory milieu and YAP activation in HPCs during PLC development.

Significance:

This work defines how hnRNPK links TNFα signaling and Hippo pathway transcription coactivator YAP in hepatic progenitor cells during primary liver tumorigenesis.
Changes in the Incidence of Cancer in Bulawayo, Zimbabwe over a 50-Year Period
Authors: Parkin Donald Maxwell , Chingonzoh Tatenda , Vuma Samkeliso , Liu Biying , Chokunonga Eric , Ndlovu Ntokozo , Borok Margaret
Published: February 2021

Background:

The cancer registry of Bulawayo (Zimbabwe) operated for 15 years in the preindependence period (1963–77), and was restarted in 2011. This allows comparison of incidence of cancers over a period of almost 50 years.

Methods:

Age-standardized rates, with SEs, were calculated for 1963–1972 and 2011–2015. Detailed results are presented for those cancers for which there was a significant (P < 0.05) change in the rates between the two periods.

Results:

There were declines in the rates of those cancers previously known to be common in East and Southern Africa (esophagus, liver, bladder), and the emergence of cancers associated with “westernization” of lifestyles (breast, prostate, large bowel). Cancers related to infection with HIV–AIDS (Kaposi sarcoma, non-Hodgkin lymphoma, eye cancers) have come to comprise a much larger proportion of the total burden, and cancer of the cervix (also AIDS-related) has shown a large increase in incidence—as elsewhere in sub-Saharan Africa (SSA). More surprising is the decline in cancer of the lung—formerly very high, but by 2011–2015, despite little change in the prevalence of smoking, rates were low—close to the average for SSA. This may relate, in part, to a decline in the numbers of miners, and ex-miners, residing in the city.

Conclusions:

The changes in incidence are largely explained by differences in past exposure to environmental risk factors.

Impact:

Few datasets from SSA can document temporal changes in the cancer epidemic on the continent. There are some anticipated observations, as well as unexpected findings meriting further investigation.
Dietary Acid Load and the Risk of Pancreatic Cancer: A Prospective Cohort Study
Authors: Shi Li-Wei , Wu Yi-Lin , Hu Jie-Jun , Yang Peng-Fei , Sun Wei-Ping , Gao Jian , Wang Kang , Peng Yang , Wu Jing-Jing , Zhong Guo-Chao
Published: February 2021

Background:

Modern Western diets are rich in acidogenic foods. Human and in vitro studies suggest a potential link between dietary acid load and cancer risk. However, no epidemiologic studies have investigated the association of dietary acid load with the risk of pancreatic cancer. Therefore, we conducted a prospective cohort study to fill this gap.

Methods:

A population-based cohort of 95,708 American adults was identified. Potential renal acid load (PRAL) and net endogenous acid production (NEAP) were used to assess dietary acid load of each subject, with greater values indicating greater dietary acid load. Cox regression was used to estimate risk estimates for pancreatic cancer incidence. Predefined subgroup analysis was used to identify the potential effect modifiers.

Results:

A total of 337 pancreatic cancer cases were observed during 848,534.0 person-years of follow-up. PRAL score was found to be positively associated with the risk of pancreatic cancer [fully adjusted HRquartile 4 vs. 1: 1.73; 95% confidence interval (95% CI), 1.21–2.48; Ptrend = 0.001] in a nonlinear dose–response pattern (Pnonlinearity = 0.012). Subgroup analysis found that the positive association of PRAL score with the risk of pancreatic cancer was more pronounced in subjects aged <65 years than in those ≥65 years (Pinteraction = 0.018). Similar results were obtained for NEAP score.

Conclusions:

Higher dietary acid load is associated with a higher risk of pancreatic cancer. Future studies should validate our findings in other populations and settings.

Impacts:

This is the first epidemiologic study suggesting that reducing dietary acid load may be useful in primary prevention of pancreatic cancer.
The Adolescent and Young Adult (AYA) Horizon Study: An AYA Cancer Survivorship Cohort
Authors: Nichols Hazel B. , Baggett Chris D. , Engel Stephanie M. , Getahun Darios , Anderson Chelsea , Cannizzaro Nancy T. , Green Laura , Gupta Parul , Laurent Cecile A. , Lin Paul C. , Meernik Clare , Moy Lisa M. , Wantman Ethan , Xu Lanfang , Kwan Marilyn L. , Mersereau Jennifer E. , Chao Chun R. , Kushi Lawrence H.
Published: February 2021

Background:

In the United States, >45,000 adolescent and young adult (AYA) women are diagnosed with cancer annually. Reproductive issues are critically important to AYA cancer survivors, but insufficient information is available to address their concerns. The AYA Horizon Study was initiated to contribute high-quality, contemporary evidence on reproductive outcomes for female cancer survivors in the United States.

Methods:

The study cohort includes women diagnosed with lymphoma, breast, melanoma, thyroid, or gynecologic cancer (the five most common cancers among women ages 15–39 years) at three study sites: the state of North Carolina and the Kaiser Permanente health systems in Northern and Southern California. Detailed information on cancer treatment, fertility procedures, and pregnancy (e.g., miscarriage, live birth) and birth (e.g., birth weight, gestational length) outcomes are leveraged from state cancer registries, health system databases and administrative insurance claims, national data on assisted reproductive technology procedures, vital records, and survey data.

Results:

We identified a cohort of 11,072 female AYA cancer survivors that includes >1,200 African American women, >1,400 Asian women, >1,600 Medicaid enrollees, and >2,500 Hispanic women using existing data sources. Active response to the survey component was low overall (N = 1,679), and notably lower among minority groups compared with non-Hispanic white women.

Conclusions:

Passive data collection through linkage reduces participant burden and prevents systematic cohort attrition or potential selection biases that can occur with active participation requirements.

Impact:

The AYA Horizon study will inform survivorship planning as fertility and parenthood gain increasing recognition as key aspects of high-quality cancer care.
Loss of 9p21 Regulatory Hub Promotes Kidney Cancer Progression by Upregulating HOXB13
Authors: Baietti Maria Francesca , Zhao Peihua , Crowther Jonathan , Sewduth Raj Nayan , De Troyer Linde , Debiec-Rychter Maria , Sablina Anna A.
Published: February 2021

Loss of chromosome 9p21 is observed in one-thirds of clear-cell renal cell carcinoma (ccRCC) and is associated with poorer patient survival. Unexpectedly, 9p21 LOH does not lead to decreased expression of the 9p21 tumor suppressor genes, CDKN2A and CDKN2B, suggesting alternative mechanisms of 9p-mediated tumorigenesis. Concordantly, CRISPR-mediated 9p21 deletion promotes growth of immortalized human embryonic kidney epithelial cells independently of the CDKN2A/B pathway inactivation. The 9p21 locus has a highly accessible chromatin structure, suggesting that 9p21 loss might contribute to kidney cancer progression by dysregulating genes distal to the 9p21 locus. We identified several 9p21 regulatory hubs by assessing which of the 9p21-interacting genes are dysregulated in 9p21-deleted kidney cells and ccRCCs. By focusing on the analysis of the homeobox gene 13 (HOXB13) locus, we found that 9p21 loss relieves the HOXB13 locus, decreasing HOXB13 methylation and promoting its expression. Upregulation of HOXB13 facilitates cell growth and is associated with poorer survival of patients with ccRCC.

Implications:

The results of our study propose a novel tumor suppressive mechanism on the basis of coordinated expression of physically associated genes, providing a better understanding of the role of chromosomal deletions in cancer.
Wind energy resource assessment of desert sites in Algeria: energy and reduction of CO2 emissions
Authors: Benmedjahed Miloud , Maouedj Rachid , Mouhadjer Samir
Published: February 2021

This paper presents a statistical analysis of wind potential of four locations in southern Algeria, namely Adrar, In Salah, Illizi and Tamanrasset, using the Weibull distribution. The evaluation the energy production by the CALORIUS 37 wind turbine taking into account the meteorological (wind and temperature and geographical (latitude, longitude and altitude) datas of these locations. The data were collected every 3 hours over 5 years and used to estimate of the annual energy produced, in order to determine the amount of three types of fossil energy (natural gas, gasoil and gasoline) preserved and the quantities of CO2 that can be avoided. The shape parameter k, varies from 2.0 (Illizi and Tamanrasset) to 2.48 (In Salah), this means that all the distributions are stable, while the scale parameters C varies from 4.6 m/s (Illizi) to 6.3 m/s (In Salah) and mean velocity v varies from 4.1 m/s (Illizi) to 5.5 m/s (Adrar), while the annual energy produced by CALORIUS 37 range from 4467.6 kWh (Illizi) to 8409.6 kWh (Adrar), the equivalent of energies range from 0.38 TEP (Illizi) to 0.72 TEP (Adrar) and the amount of carbon dioxide (CO2 ) that we can provide varies from 0.90 TE-CO2 (natural gas power plant in Illizi ) to 2.24 TE-CO2 (gasoil power plant in Adrar).
Renewable energy production based on solar power and magnetic field prototype in Bangladesh
Authors: Qays Ohirul , Yasmin Farhana
Published: February 2021

Though modern technology of new era is mostly dependent on power sector entirely, the current energy scenario is showing a serious negative effect for the last few decades. Comparatively, Bangladesh is facing a precarious effect because of the scarcity of fossil-fuel dissipation. To accomplish the power demand resolution, a new type of power generation is proposed in this research paper. Magnetic flux and solar irradiation is combined to get maximum power outcome. The PV panel supplies the maximum power in the peak solar radiation and terminates the energy stream at night time. However, the floating generator can supply its maximum creation day or night time according to the movement of water wave tendency. For this reason, a PV-floating Generator based integrated renewable energy scheme is inspected in this venture. The experimental result shows its real-world validation (Maximum 14.5 Watt output) comparing to conventional methods.
Effect of Sleep Disturbances on Blood Pressure
Authors: Makarem Nour , Alcántara Carmela , Williams Natasha , Bello Natalie A. , Abdalla Marwah
Published: February 2021

This review summarizes recent literature addressing the association of short sleep duration, shift work, and obstructive sleep apnea with hypertension risk, blood pressure (BP) levels, and 24-hour ambulatory BP. Observational studies demonstrate that subjectively assessed short sleep increases hypertension risk, though conflicting results are observed in studies of objectively assessed short sleep. Intervention studies demonstrate that mild and severe sleep restriction are associated with higher BP. Rotating and night shift work are associated with hypertension as shift work may exacerbate the detrimental impact of short sleep on BP. Further, studies demonstrate that shift work may increase nighttime BP and reduce BP control in patients with hypertension. Finally, moderate to severe obstructive sleep apnea is associated with hypertension, particularly resistant hypertension. Obstructive sleep apnea is also associated with abnormal 24-hour ambulatory BP profiles, including higher daytime and nighttime BP, nondipping BP, and a higher morning surge. Continuous positive airway pressure treatment may lower BP and improve BP dipping. In conclusion, efforts should be made to educate patients and health care providers about the importance of identifying and treating sleep disturbances for hypertension prevention and management. Empirically supported sleep health interventions represent a critical next step to advance this research area and establish causality.
Atrial Fibrillation Following Patent Foramen Ovale Closure
Authors: Chen Jessie Ze-Jun , Thijs Vincent N.
Published: February 2021

Background and Purpose:

Multiple studies evaluated whether patent foramen ovale (PFO) closure reduces the risk of ischemic stroke. One commonly reported complication of PFO closure is the development of atrial fibrillation (AF), which is itself a powerful stroke risk factor that requires specific management. This study aims to evaluate the frequency of AF in patients post-percutaneous closure of PFO and the clinical factors that predict AF detection.

Methods:

Studies were identified by systematically searching EMBASE and MEDLINE databases on July 11, 2019. Meta-analysis of proportions was performed, assuming a random-effects model.

Results:

A total of 6 randomized controlled trials and 26 observational studies were included, comprising 3737 and 9126 patients, respectively. After PFO closure, the rate of AF development was 3.7 patients per 100 patient-years of follow-up (95% CI, 2.6–4.9). The risk of AF development is concentrated in the first 45 days post-procedure (27.2 patients per 100 patient-years [95% CI, 20.1–34.81], compared with 1.3 patients per 100 patient-years [95% CI, 0.3–2.7]) after 45 days. Meta-regression by age suggested that studies with older patients reported higher rate of AF (
P
=0.001).

In medically treated patients, the rate of AF development was 0.1 per 100 patient-years of follow-up (95% CI, 0.0–0.4). Closure of PFO is associated with increased risk of AF compared with medical management (odds ratio, 5.3 [95% CI, 2.5–11.41];
P
<0.001).

Conclusions:

AF is more common in PFO patients who had percutaneous closure compared with those who were medically treated. The risk of AF was higher in the first 45 days post-closure and in studies that included patients with increased age.
The Implementation Review Mechanism of the UN Convention against Transnational Organized Crime (UNTOC)
Authors: Tennant Ian , Mahadevan Prem
Published: February 2021

When the UNTOC came into being in 2000 at a signing ceremony in the Sicilian city of Palermo, it was hoped that the convention would empower civil society to fight transnational organized crime (TOC), alongside the state. This article examines the Implementation Review Mechanism, agreed by the Convention’s Parties in Vienna in 2018, which formalises the process by which civil society will be able to engage in monitoring and improving the implementation of the Convention. The article analyses the provisions of the mechanism pertaining to civil society participation, and finds that the UNTOC Review Mechanism, despite being an achievement of sorts, remains weak as it pertains to the opportunities for civil society to influence its outcomes. But despite its drawbacks, there are opportunities to be seized. Civil society, especially as regards those individuals and organizations working on organized crime issues, is evolving and growing. The mechanism exists where nothing similar has been seen before in the TOC sphere, and there is a critical mass of States parties that are willing to open the door to civil society with the aim of optimizing the outcomes of the mechanism. It is now up to civil society to organize itself for the upcoming challenge.
The Book Revealing the Future in a Religion without Books: the Apocalyptic Visions of Yezidi Seers
Authors: Spät Eszter
Published: February 2021

This article studies the “book,” or defter, of Yezidi seers in Northern Iraq. Following an oral religion in an Islamic environment where only “people of the Book” enjoyed legitimate status and social acceptance, Yezidis have developed various strategies to compensate for the absence of a written sacred book. The most unique among these is the phenomenon of “falling into book,” which refers to the altered state of consciousness experienced by some Yezidi seers. “Falling into book” provides the seer with a glimpse into both the past and the future, thus serving as a source of divination and prognostication, which ranges from addressing personal problems to foretelling the (usually apocalyptic) fate of the Yezidi community and the world. Thus the “book” of the seers is perceived to be a kind of “heavenly knowledge,” equal or even superior to the revealed texts of bookish religions.
The Man-Bird Mountain: Writing, Prophecy, and Revelation in Early China
Authors: Pregadio Fabrizio
Published: February 2021

The Taoist Canon (Daozang) contains a remarkable illustration entitled Renniao shan tu, or Chart of the Man-Bird Mountain, found in a text originally dating from the mid-fifth century. Other Taoist works describe this mountain as the ultimate origin of revealed scriptures and even of the entire Canon. In this article, I examine three main themes related to the Chart. The first is the role of birds in traditional accounts of the origins of Chinese writing. The second theme concerns the function of birds in the revelation of prophetic charts and texts, described in Han-dynasty “weft texts.” The third theme is the early narratives focused on the so-called “winged men” (yuren). This is followed by an analysis of the Chart, including its inscriptions, and of the text that contains it. An appendix provides translations of the inscriptions and of similar passages found in other Taoist sources.
Cyathea Sm. (Cyatheaceae) on Trindade Island (Brazil): An integrative approach
Authors: FARIA ALLAN LAID ALKIMIM , SALINO ALEXANDRE , CARVALHO-SILVA MICHELINE , STECH MICHAEL , AMORIM EDUARDO TOLEDO DE , CÂMARA PAULO EDUARDO AGUIAR SARAIVA
Published: February 2021

Trindade is a Brazilian oceanic island approximately 1,100 km from the American mainland. The Cyathea Sm. plants from Trindade were originally considered an endemic species, Cyathea copelandii Kuhn & Luerssen, but later included in Cyathea delgadii Sternb. Based on molecular data (trnL-trnF, trnG-trnR and rbcL-accD), morphometric analysis of leaf characters, scanning electron microscopy of indusia and spores, and habitat suitability modeling, the present study confirms the status of C. copelandii as a synonym of C. delgadii. Intraspecific molecular variation suggests phylogeographic structuring in C. delgadii and differentiation between the coastal Atlantic Forest domain and the Cerrado domain (savanna) in the interior of Brazil. The Trindade populations are more closely related to the Atlantic Forest populations, indicating a colonization of the island from the latter area.
Triandra pellabergensis (Hyacinthaceae subfam. Urgineoideae), a new genus and species from Pella se Berge, Northern Cape Province, South Africa
Authors: MARTÍNEZ-AZORÍN MARIO , CRESPO MANUEL B. , ALONSO-VARGAS MARÍA ÁNGELES , CROUCH NEIL R. , PINTER MICHAEL
Published: February 2021

Within the framework of a taxonomic revision of subfamily Urgineoideae based on morphological, genetic and phytogeographic data covering numerous samples from its whole range of distribution, we here describe a new genus and species from Pella se Berge in northwestern South Africa. Triandra gen. nov. is easily characterized by the absence of stamens associated with the outer tepal whorl, therefore having only three stamens per flower, a character previously unknown in Hyacinthaceae. Triandra pellabergensis sp. nov. produces hypogeal bulbs with filiform proteranthous leaves, spurred bracts, lax racemes with few, nodding, nocturnal flowers and erect capsules with the withered tepals persisting atop. The new species resembles Urginea revoluta in general morphology, although this latter species has six stamens per flower, a different seed morphology, a distinct phytogeographic pattern, and a distant phylogenetic relationship. A complete morphological description is presented for the new genus and species, including data on its biology, ecology and distribution.
Assimilation of a Coordinated Fleet of Uncrewed Aircraft System Observations in Complex Terrain: EnKF System Design and Preliminary Assessment
Authors: Jensen Anders A. , Pinto James O. , Bailey Sean C. C. , Sobash Ryan A. , de Boer Gijs , Houston Adam L. , Chilson Phillip B. , Bell Tyler , Romine Glen , Smith Suzanne W. , Lawrence Dale A. , Dixon Cory , Lundquist Julie K. , Jacob Jamey D. , Elston Jack , Waugh Sean , Steiner Matthias
Published: February 2021

Uncrewed aircraft system (UAS) observations collected during the 2018 Lower Atmospheric Process Studies at Elevation—a Remotely Piloted Aircraft Team Experiment (LAPSE-RATE) field campaign were assimilated into a high-resolution configuration of the Weather Research and Forecasting Model using an ensemble Kalman filter. The benefit of UAS observations was assessed for a terrain-driven (drainage and upvalley) flow event that occurred within Colorado’s San Luis Valley (SLV) using independent observations. The analysis and prediction of the strength, depth, and horizontal extent of drainage flow from the Saguache Canyon and the subsequent transition to upvalley and up-canyon flow were improved relative to that obtained both without data assimilation (benchmark) and when only surface observations were assimilated. Assimilation of UAS observations greatly improved the analyses of vertical variations in temperature, relative humidity, and winds at multiple locations in the northern portion of the SLV, with reductions in both bias and the root-mean-square error of roughly 40% for each variable relative to the benchmark run. Despite these noted improvements, some biases remain that were tied to measurement error and/or the impact of the boundary layer parameterization on vertically spreading the observations, both of which require further exploration. The results presented here highlight how observations obtained with a fleet of profiling UAS improve limited-area, high-resolution analyses and short-term forecasts in complex terrain.
The Effect of Monaurally Fitted Hearing Aid Use on the Evolution of Presbycusis
Authors: Dunya Gabriel , Najem Fadi , Mailhac Aurelie , Abou Rizk Samer , Bassim Marc
Published: February 2021

Objective:

The effect of hearing aid use on the evolution of presbycusis has not been well described in the literature, with only a handful of publications addressing this topic. This paper aims to evaluate the long-term use of amplification and its effect on pure-tone thresholds and word recognition scores.

Method:

Monaurally fitted patients were followed with serial audiograms. Data was collected from hearing aid centers. Seventy-seven patients with presbycusis met the inclusion criteria and participated in the present study. The progression of hearing loss in both pure tone thresholds and word recognition scores were compared between the hearing aid ears (HA), and the non-hearing aid ears (NHA). Pure tone thresholds were analyzed by comparing the pure tone average at the initial and last audiograms. Word Recognition Scores (WRS) were analyzed using the model of Thornton and Raffin (1978), and by comparing the change in the absolute values of WRS from the initial to the last audiogram between the HA ear and the NHA ear.

Results:

No significant difference in pure-tone thresholds between the HA ear and NHA ear was found at the last audiogram ( P = .696), even after dividing the patients into groups based on the duration of amplification. Both methods of analysis of patients’ WRS showed a statistically significant worsening in NHA ( P < .05).

Conclusion:

The present study supports the previously defined auditory deprivation effect on non-fitted ears, which showed worsening of word recognition over time and no effect on pure tone average. It provides an additional argument for the counseling of patients with presbycusis considering amplification, and highlights the importance of bilateral amplification in preserving the residual hearing of hearing impaired patients.
Inference on P(Y<X) Based on Record Values for Generalized Pareto Distribution
Authors: Chacko Manoj , Mathew Shiny
Published: February 2021

In this article, the estimation of [Formula: see text] is considered when [Formula: see text] and [Formula: see text] are two independent generalized Pareto distributions. The maximum likelihood estimators and Bayes estimators of [Formula: see text] are obtained based on record values. The Asymptotic distributions are also obtained together with the corresponding confidence interval of [Formula: see text].

AMS 2000 subject classification: 90B25
Narratives of a place named Ellora: Myths, culture and politics
Authors: Sharma Mahesh
Published: February 2021

Ellora is the place where caves associated with different sects and religions were carved over a span of at least 800 years. While the caves, narrowly understood, have been the subject of many studies, the ‘place’, as a site of political and social interaction, has been largely neglected. Ellora was larger than just the caves; it was a place with a long history where traders, monks, artisans and armies brought in different ideas, reconsidered the old and innovated upon cultural traditions that reflected on their own identities and their relationship with Ellora. These people and their actions stamped the place with meaning and identity, which accrued over time—sometimes exclusive, at other times hybrid, but inevitably transformative. Ellora was an important site that conjured multivalent sensibilities, more complex than many other places. This article uses toponym as an analytic focus to bring into play different subjects—the historical agents, religious organisations, monuments and textual materials—that provided structure and meaning to the Ellora Caves at different historical junctures. It argues how the place and people in power have different kinds of relationships with the past, especially when it is not their past but one that they need to master. The impact of material change and transition in the production of historical materials is particularly striking when studied in the long duration with focus on a relatively small but politically significant site.
Research on online management system of network ideological and political education of college students
Authors: Li Kang , Jing Maliang , Tao Xingwang , Duan Yinxiang
Published: February 2021

With the development of the network society, the life of college students is shrouded by the network society, and there are more and more channels for them to contact various kinds of information, which brings new challenges to their ideological and ideological behaviors. We need to use the correct, active, positive way to increase the ideological network political education of students. College students' ideological and political education also gradually stepped into the network education wave, in the process of the new era of university education, network education is more and more important in the process of ideological and political education. Inn carrying out the education work in colleges and universities, we should departure from the specific teaching content, in order to effectively promote the physical and mental development of college students, and ensure the ideological and political education of college students. The development of network provides a broader path for ideological and political education, and network education is also a new challenge for ideological and political educators. This paper proposes an efficient online education management system based on cloud computing technology, which improves the traditional information management process and information classification algorithm, and can be a good online education task.
Research on comprehensive evaluation method of Bayu cultural resources development based on DEMATEL
Authors: Qin Wei , Lin Qingna
Published: February 2021

Ba-Yu culture resources development of many influence factors, natural, businesses, communities, urban, rural, historical and cultural resources is composed of all the important elements of cultural resources, elements and related links between has always been culture researchers think, is the traditional quantitative analysis method can't combine with cultural resources research one of the important factors affecting, based on the DEMATEL method, will form a good complementary to the traditional research methods, more objective reflect the influence of the relationship between elements and, by building the evaluation system for the development of cultural resources, Form scientific and effective system of cultural resources development impact factors, the combination of qualitative and quantitative way, science reflects social common recognition of cultural resources development, better reflect the cultural resources elements influence each other and promote scientific achievements, for the regional government, enterprises and individuals in the culture industry investment in the corresponding decision system, scientific, objective decision-making system, through research will eventually realize the dynamic monitoring system for the development of cultural resources, will effectively improve the efficiency and effect of regional culture resources development, realize the rapid development of the regional cultural industry.
Abraham Maslow: The Last Weekend
Authors: Morrell Marylyn , Hoffman Edward
Published: February 2021

Abraham Maslow died suddenly of a heart attack in June 1970 at the peak of his intellectual renown and influence. This is an account of his final weekend as described in hand-written notes by the first author, who was a frequent visitor to the Maslow home in the San Francisco Bay area at the time. This account, which sheds new light on Maslow’s personal life, interests, and plans, has been edited for readability with contextual notes provided by the second author.
The ethics of ethnographic methods in conflict zones
Authors: Krause Jana
Published: February 2021

This article examines the ethics of using ethnographic methods in contemporary conflict zones. Ethnographic research is an embodied research practice of immersion within a field site whereby researchers use ethnographic sensibility to study how people make sense of their world. Feminist, conflict and peacebuilding scholars who research vulnerable populations and local dynamics especially value ethnographic approaches for their emphasis on contextual understanding, human agency, egalitarian research relationships and researcher empathy. While immersion leads to knowledge that can hardly be replaced by using more formal approaches, it also elicits ethical dilemmas. These arise not only from the specific research context but also from who the researcher is and how they may navigate violent and often misogynous settings. I argue that many dilemmas may and perhaps should not be overcome by researcher skill and perseverance. Instead, ethical challenges may lead researchers to adopt limited and/or uneven immersion in their field site, not as failed or flawed ethnography but as an ethical research strategy that incorporates ethnographic sensibility to a varying extent. Examining why researchers may opt for limited and uneven immersion is important because in conflict research, stereotypes of the intrepid (male) researcher with a neutral gaze still tend to mute open discussions of how gender, race, ethnicity, nationality, class and other background factors inevitably shape immersion. This article seeks to contribute to creating discursive space for these conversations, which are vital for researchers to analyse, reflect and write from the position of a ‘vulnerable observer’ and incorporate greater transparency in the discussion of research findings.
Digital equality requires more than access
Authors: Rafalow Matthew H.
Published: February 2021

Conversations about digital inequality in education often revolve around access to technology. However, research into youth culture has shown that many Black and Latinx teens are able to access technology and have developed the same digital skills as their white peers. Social scientist Matt Rafalow observed three California middle schools where students had similar levels of access to digital technologies despite being from different racial and class backgrounds and found that teachers perceived students’ technological abilities differently. Wealthy white students’ digital play was seen as essential to learning, while Asian American and Latinx students’ skills were seen as either a threat to their learning or irrelevant to it. Addressing digital inequality will require schools to also address the racial and class prejudice that leads teachers to view students’ abilities differently.
Washington View: Schools that stayed open: Lessons from St. Charles Parish
Authors: Ferguson Maria
Published: February 2021

Maria Ferguson talks with Ken Oertling, superintendent of the Saint Charles Parish Public Schools in Louisiana, to learn more about how the school opened its doors to in-person learning in fall 2020, during the COVID-19 pandemic. The plan for reopening required district leaders to juggle a variety of logistical challenges and communicate clearly at every step. And the physical and mental health of staff and students became an even higher priority than before.
How (Not) to Control for Population Size in Ecological Analyses
Authors: Rohr Benjamin , Martin John Levi
Published: February 2021

It is common for social scientists to use formal quantitative methods to compare ecological units such as towns, schools, or nations. In many cases, the size of these units in terms of the number of individuals subsumed in each differs substantially. When the variables in question are counts, there is generally some attempt to neutralize differences in size by turning variables into ratios or by controlling for size. But methods that are appropriate in many demographic and epidemiological contexts have been used in settings where they may not be justified and may well introduce spurious relations between variables. We suggest local regressions as a simple diagnostic and generalized additive models as a superior modeling strategy, with double-residualized regressions as a backup for certain cases.
Approaching honor and shame with humility: Limitations to our current understanding
Authors: Dunaetz David R
Published: February 2021

Although honor and shame have been popular missiological themes in the last decade, there are several limitations associated with the concepts that occur in both the missiological literature and the secular anthropological, sociological, and psychological literature. The first set of limitations concerns the meaning of honor and shame. Their definitions vary greatly from author to author. Some authors consider honor and shame to be emotions internal to the individual and others consider them as a measure of one’s social status, something external to the individual. Similarly, there is often no distinction made between shame and shame-proneness. Their relationship with other self-conscious emotions (guilt, embarrassment, and pride) is not clear. Often the distinction between vicarious and individual shame and honor is blurred. The second set of limitations concerns the lack of understanding of how honor and shame relate to culture. Since shame dynamics exist in every culture, it is not clear what is meant by a “shame culture.” Modern conceptions of culture tend to view culture as a phenomenon that is due to psychological processes within individuals, rather than external to the individual. Characteristics of cultures are described by positions on dimensions. Shame cultures are often defined as those which are more collectivistic (versus individualistic). However, many definitions of honor and shame indicate that the dimension of cultural tightness (or uncertainty avoidance) may be just as relevant for understanding shame dynamics, and the cultural dimension of power distance may also be relevant. In light of these limitations, missiologists need to approach the concepts of honor and shame with humility.
Gas pipeline leakage detection in the presence of parameter uncertainty using robust extended Kalman filter
Authors: Jahanian Mohadese , Ramezani Amin , Moarefianpour Ali , Aliari Shouredeli Mahdi
Published: February 2021

One of the most significant systems that can be expressed by partial differential equations (PDEs) is the transmission pipeline system. To avoid the accidents that originated from oil and gas pipeline leakage, the exact location and quantity of leakage are required to be recognized. The designed goal is a leakage diagnosis based on the system model and the use of real data provided by transmission line systems. Nonlinear equations of the system have been extracted employing continuity and momentum equations. In this paper, the extended Kalman filter (EKF) is used to detect and locate the leakage and to attenuate the negative effects of measurement and process noises. Besides, a robust extended Kalman filter (REKF) is applied to compensate for the effect of parameter uncertainty. The quantity and the location of the occurred leakage are estimated along the pipeline. Simulation results show that REKF has better estimations of the leak and its location as compared with that of EKF. This filter is robust against process noise, measurement noise, parameter uncertainties, and guarantees a higher limit for the covariance of state estimation error as well. It is remarkable that simulation results are evaluated by OLGA software.
Event-triggered boundary quantization control for flexible manipulator based on partial differential equations dynamic model
Authors: Wang Jiacheng , Liu Jinkun
Published: February 2021

In this paper, we consider boundary control for a single-link flexible manipulator system described by partial differential equations (PDEs). Existing researches on controller design rarely consider the problem of communication capacity constrains during signal transmission. To deal with this problem, an adaptive control is designed to achieve the input quantization by using the random quantizer. Besides, a triggering event is addressed on the basis of relative threshold strategy for relieving communication load between controller and actuator. The proposed scheme is able to ensure that all closed-loop signals are globally uniformly bounded, and the angular tracking error and vibration converge to a residual set. Simulation results are presented to illustrate the effectiveness of the proposed scheme.
RFID multi-tag dynamic detection measurement based on conditional generative adversarial nets and YOLOv3
Authors: Li Lin , Yu Xiaolei , Liu Zhenlu , Zhao Zhimin , Zhang Ke , Zhou Shanhao
Published: February 2021

The quality of multi-tag imaging greatly affects the effective detection of multi-tag. When multi-tag moves rapidly, the image may have serious dynamic blur, and tags can not be detected efficiently. In previous work, it is generally assumed that blur kernel and noise stationary to improve image quality. However, the dynamic deblurring of Radio Frequency Identification (RFID) multi-tag imaging is an ill-posed inverse problem. In this paper, firstly, blur-sharp multi-tag image pairs are made by superimposing and averaging the adjoin random frames. Then, we propose blind deblurring for dynamic RFID multi-tag imaging based on conditional generative adversarial nets (CGANs), which adds perceptual loss and content loss to generator to make image sharper. Finally, tags are detected by YOLOv3 in real time in end-to-end manner. Experimental results demonstrate that PSNR is at least 0.56dB higher and speed is at least 31.25 % faster than that of the current improved convolution neural networks (CNN). CGANs can remove image blur better, which has great superiority in the field of dynamic multi-tag imaging. In addition, YOLOv3 detects multi-tag quickly, thereby improving the detection accuracy.
Molecular simulation on mechanism of thiophene hydrodesulfurization on surface of Ni2P
Authors: Du Songjian , Li Tingting , Wang Xinwei , Zhang Liqiang , Yang Zhengda , Lin Riyi , Zhu Tanxiao
Published: February 2021

Hydrodesulfurization reaction, as the last step of hydrothermal cracking reaction, is of great significance for the reduction of viscosity and desulfurization of heavy oil. Based on Density Functional Theory and using Dmol3 module of Materials Studio, this research simulated the adsorption and hydrodesulfurization of thiophene on Ni2P (001) surface, and discussed the hydrodesulfurization reaction mechanism of thiophene on Ni2P (001) surface. It was found that the direct hydrodesulfurization of thiophene had more advantages than the indirect hydrodesulfurization of thiophene. Finally, the optimal reaction path was determined: C4H4S+H2→C4H6.
Translating a Chinese approach? Rural distribution and marketing in Ghana’s phone industry
Authors: Lu Miao
Published: February 2021

Ghana’s mobile phone markets are currently dominated by a Chinese company called Transsion. Based on 7-month ethnographic research, this article examines Transsion’s distribution and marketing practices in Ghana, which are largely labor-intensive, rural-centric, low value-added, and lower-class-oriented. Taking a historical approach, this article reveals that this business strategy originated in China and has been translated to Ghana by a wide variety of translators. By elaborating various translation scenarios, this article demonstrates that translation as a practice, be it cultural, technological, or managerial, is a complicated process with tensions, adaptations, and innovations. As a tech company from the Global South, Transsion provides a critical case to think beyond the urban-centric and high value-added business model of Silicon Valley-type companies.
“Because I said so!”: Mothers’ conventional conflict justifications related to resolution and child behavior problems and temperamental reactivity
Authors: Tollossa Ruhama M. , Nelson Jackie A.
Published: February 2021

A common strategy parents use to justify their point of view during parent–child conflict is conventional reasoning, which focuses on child obedience to authority. In this brief report, we examined mothers’ use of conventional justification during mother–child conflict discussions in relation to the resolution reached and children’s behavior problems and temperamental reactivity concurrently and longitudinally. Participants included 190 mothers and their 5- to 7-year-old children. Dyads engaged in a conflict discussion task in the laboratory, which was coded for mothers’ use of conventional justification and the type of resolution reached. Mothers reported on child behavior problems and temperamental reactivity then and 1 year later. Results showed mothers used more conventional reasoning during conflict discussions that resulted in a win/loss resolution compared to a compromise. Mothers’ conventional reasoning was concurrently associated with more child externalizing behaviors and temperamental reactivity at Year 1. Mothers’ conventional reasoning did not relate to changes in child behaviors over time. Findings are discussed in terms of mothers’ conceptions of parental authority and possible directions of effects.
Prediction value of EuroSCORE II in total arterial revascularization and its usage in the evaluation of postoperative complications: Single-center experience
Authors: Milutinovic Aleksandar V , Krasic Stasa D , Zivkovic Igor S , Cirkovic Andja M , Lokas Slobodan Z , Jovanovic Milos M , Milojevic Predrag S , Peric Miodrag S
Published: February 2021

Background

Total arterial revascularization is the most durable and technically the most demanding type of coronary artery bypass grafting procedure. It has proven long-term supremacy in comparison to conventional coronary artery bypass grafting. In our study, we investigated the reliability of EuroSCORE II as a predictor of intrahospital death. We showed its impact on adverse perioperative events.

Methods

In this nonrandomized prospective study, we analyzed 116 consecutive patients who underwent the total arterial revascularization procedure at our Institute from January 2011 until the present. For myocardial revascularization, the most suitable combinations with left internal mammary artery, right internal mammary artery, and radial artery grafts were used. Main fact in this research was intrahospital mortality value in comparison with the value predicted.

Results

There were 104 (89.7%) males and 12 (10.3%) females. Mean preoperative EuroSCORE II prediction value was 1.98% and postoperative we obtained 1.72%. Postoperative redo for bleeding was 6%. Positive correlation was proven between the EuoroSCORE II value and intensive care unit stay (0.452; p < 0.001). Among patients who received two internal mammary arteries, the highest EuroSCORE II was among those with presternal wound infection (p = 0.005). Patients with bilateral internal mammary arteries and diabetes showed that they have the highest values of EuroSCORE II and, at the same time, that they are extremely prone to wound problems.

Conclusions

We achieved a lower intrahospital mortality level than it was predicted with preoperative EuroSCORE II value. This tool is a reliable method for preoperative death risk calculation in this group of patients.