bluuebunny/crossref_metadata_2025 huggingface dataset:
Probiotics-based Anticancer Immunity in Thyroid Cancer
Authors: Pichai Tamilkani , Selvaraj Kalaiselvi , Muthusamy Karnan , Pulikondan francis Steffi , Chelliah Ramachandran , Barathikannan Kaliyan , Pulikondan francis Mishel , Annamalai Panneerselvam , Oh Deog-Hwan , Selvakumar Vijayalakshmi
Published: July 2023

Cancer is one of the major diseases that seriously endanger human health
worldwide. The risk of developing cancer depends on genetic factors and the body's
immune system. The intestinal microbiome plays an essential role in maintaining
homeostasis in the human body. After cardiovascular disease, the second-largest illness
in terms of morbidity and mortality rate is cancer. Cancer has always been the focus of
human attention worldwide, which makes it a research hotspot in the medical field. In
recent years, the consumption of probiotics has been fetching in health-promoting
foods for humans, therapeutic, prophylactic and growth supplements for animal
production and human health. In medicine, various studies have demonstrated that
probiotics can help in improving the immune system and intestinal health and the effect
of probiotic therapy on antitumor treatment-related side effects; combined use of
probiotic strains did have a positive protective effect for patients with specific immune
function. Healthy gut microbiota has positive impacts not just on immune system
activity but also on thyroid function. Dysbiosis has been detected in autoimmune thyroid diseases (AITD) and thyroid cancer, where many carcinogenic and inflammatory
bacterial strains were found. The nature of the gut microbiome also influences the
availability of important micronutrients for the thyroid gland. Iodine, iron, and copper
are required for thyroid hormone synthesis, selenium and zinc are required for T4 to T3
conversion, and vitamin D aids in immune response regulation. These micronutrients
are frequently lacking in AITDs, and lead to thyroid dysfunction. Thyroid-stimulating
hormone (TSH) and T3 levels may fluctuate due to bariatric surgery, resulting in
insufficient absorption of essential nutrients. Probiotic supplementation positively
affected thyroid hormones and thyroid function in general. This chapter summarizes
the role, mechanism of probiotics, clinical trials and effects of probiotics in thyroid
cancer.
Probiotics-based Anticancer Immunity In Lymphomas
Authors: Chaudhari Archana , Patel Swati , Kumar Dwivedi Mitesh
Published: July 2023

The gut microbiome can play an important role in maintaining homeostasis
in the human body. An imbalance in the gut microbiome can lead to pro-inflammatory
immune responses and the initiation of disease processes, including cancer.
Lymphocytes play a significant role in the reaction to bacterial colonization, mainly by
prompting a safe reaction to initiation. Most immunologically inhabitant cells are
continually signaled by dendritic cells or other antigen-presenting cells that collect
intestinal samples. Therefore, the microbiota is a pivotal contributor to developing
lymphoma, and specific changes to microbiota composition could help prevent the risk.
Microbial morphology can affect and control humanoids. The difference in the
composition of these microbes is associated with tumor development. Moreover, with
the increased exploration and knowledge of the connection between human microbiota
and carcinogenesis, the use of these findings to predict, prevent, or diagnose
lymphomas has attracted great attention. Probiotics have gained increasing medical
significance due to their beneficial effect on the human body, which has been linked to
the prevention and support of the treatment of many chronic diseases, including cancer,
in the absence of side effects. Chemotherapy and immunotherapy are extensively used
for the treatment of lymphomas. But these treatments have various side effects. There
is much evidence that probiotics can help in preventing cancer and support anticancer
therapy. This chapter presents the latest advances in research into the effectiveness of
probiotics in the prevention and treatment support of lymphoma. In addition, the
chapter also describes the potential mechanisms of probiotic chemoprevention and the
advisability of using probiotics in the prevention of lymphoma.
Probiotic Formulations For Anticancer Immunity
Authors: Parhi Rabinarayan , Das Nirupam
Published: July 2023

Probiotics are defined as “viable microorganisms which, when administered
in adequate amounts, promote health benefits on the host”. These health benefits may
include maintaining a healthy gut microbiota, reducing cholesterol levels, formation of
antimicrobial agents and vitamins, competitive inhibition of pathogenic bacteria in
terms of attachment site and nutrition, immunity-boosting, improvement of calcium
absorption, preventing constipation, and increased trans-epithelial resistance. Cancer is
expressed as the abnormal division and reproduction of cells and has a multifactorial
pathology. In mortality, cancer is in second place worldwide, which is evident from the
report that one out of every four deaths in the USA is due to cancer. Furthermore, the
prevalence of cancer is 24% and 21% for men and women, respectively. Probiotics
used in the prevention and treatment of cancer often prevent early death due to
complications caused by infection, particularly in GIT. The current article mainly
discusses different conventional and non-conventional formulations of probiotics. It
also discusses probiotics and immunity against cancer, safety, and current regulation
regarding probiotics.
Embracing E-Learning for Enhanced Learning Experiences in the Faculty of Economics and Business, Universitas Palangka Raya
Authors: Suherman Suherman , Sukmani Meylinda
Published: July 2023

Community service, one of the main tasks according to Tridharma, was carried out to optimize e-learning in the learning process for lecturers and students of the Faculty of Economics and Business (FEB), University of Palangka Raya (UPR). The issue being discussed was e-learning not being optimally used in FEB due to lecturers’ and students’ perceptions that e-learning was not a user-friendly platform. Hence to solve this problem, several implementation methods were being used, which were online and offline coaching clinics on the use of e-learning for lecturers, e-learning workshops for students, preparation of effective guidance modules, and creation of e-learning Standard Operating Procedures (SOP). The result after implementing the community service activities showed that the perceptions about e-learning were resolved after attending the community service activities which resulted in the growth of users from the lecturers and students.
ANALYSIS THE EFFECTIVENESS OF CNC TURNING MACHINES TYPE XTRA 420 USING THE OVERALL EQUIPMENT METHOD EFFECTIVENESS (OEE)
Authors:   Mechanical Engineering Department, Universitas Brawijaya, Arifin Arifin , Tama Ishardita , Sumantri Yeni
Published: July 2023

The development of the manufacturing industry is increasing every year, of course this makes competition in the manufacturing industry increasingly stringent. This research was conducted at PT. Tjokro Bersaudara Gresik, focused on CNC Turning machines with the type CNC Lathe Machine XTRA 420, namely machines used to produce various types of automotive parts and based on data collected regarding the effectiveness of the machine, it shows that the machine has not fully worked effectively. This is indicated by the presence of downtime data, engine speed reduction data, and product data that does not meet specifications. To find out how good the effectiveness of a machine is, it can measure the OEE value of the machine.. It can be concluded that the effectiveness rate (OEE) of CNC Turning machines in the January-August 2022 period is between 54.16% to 59.91% with an average of 57.55% (still below the ideal OEE value of 85%) with a percentage six big losses of 42.45%
On the Torsional Rigidity of Orthotropic Beams with Rectangular Cross Section
Authors: Baksa Attila , Ecsedi István , Lengyel Ákos József , Gönczi Dávid
Published: July 2023

The paper deals with the torsional rigidity of homogenous and orthotropic beam with rectangular crosssection. The torsional rigidity of the considered beam is defined in the framework of the Saint-Venant theory ofuniform torsion. Exact and approximate solutions are given to the determination of the torsional rigidity. The shapeof cross section is determined which gives maximum value of the torsional rigidity for a given cross-sectional area.The dependence of torsional rigidity as a function of the ratio shear moduli of beam is also studied.
Venous thromboembolism prophylaxis: Nurses' perceived knowledge and barriers
Authors: Alshammari Mohammed Qaydhi , Mostoles Romeo Jr. , Alharbi Jalal
Published: July 2023

Nurses, as primary healthcare providers who maintain regular patient contact, play a crucial role in preventing venous thromboembolism (VTE). This study aims to explore nurses' perceptions, knowledge, and barriers related to VTE prevention. A descriptive cross-sectional study was conducted among 263 staff nurses in governmental hospitals in the Hail region, Kingdom of Saudi Arabia. Data collection took place between January and May 2022. The majority of nurses considered VTE prevention to be an important issue (mean = 4.03±0.614) and perceived the current use of anticoagulant strategies as effective (mean = 2.91±1.16). However, nurses expressed some uncertainty regarding the safety of the current anticoagulant use (mean = 3.79±0.822) and felt that they underutilized available anticoagulant strategies (mean = 2.69±1.01). Generally, nurses demonstrated a good level of knowledge about VTE (83.2%). Gender was found to significantly influence knowledge (t = -2.841; p < 0.005), perception (t = -7.919; p < 0.000; mean = 3.85±0.707), and barriers (t = -4.661; p < 0.000). Regarding age, significant differences were observed in knowledge (F = 5.665; p < 0.004; mean = 15.87±4.39) and perception (F = 13.401; p < 0.000; mean = 4.16±0.782). No significant differences were found in educational attainment, work experience, and position concerning knowledge, perception, and barriers. The working area was found to have a significant impact on knowledge (F = 4.657; p < 0.000), perception (F = 4.347; p < 0.001), and barriers (F = 4.257; p < 0.001). By providing comprehensive and consistent patient education, nurses can play a critical role in minimizing morbidity and mortality rates associated with VTE, making VTE prevention a vital aspect of their responsibilities.
Endometrioid Carcinoma of the Uterine Corpus With a Micropapillary Component: A Novel Prognostic Factor For Metastasis
Authors: MOCHIZUKI KUNIO , OYAMA KEISUKE , TANAKA KOTA , FUKASAWA HIROKO , KONDO TETSUO
Published: July 2023

Background/Aim: Micropapillary pattern is a morphologically distinctive form of carcinoma composed of small, hollow, or morula-like clusters of cancer cells surrounded by clear stromal spaces. The neoplastic cells characteristically display a reverse polarity, also known as an ‘‘inside-out’’ growth pattern, that is linked to higher frequencies of lymphovascular invasion and lymph nodal metastasis. To the best of our knowledge, it has not been previously recognized in uterine corpus. Case Report: We report 2 cases of endometrioid carcinoma of the uterine corpus with a micropapillary component. In these cases, histological examination identified an endometrioid carcinoma that had invaded the myometrial layer. The carcinoma cells that constructed the micropapillary components were immunohistochemically positive for EMA. They lined the stromal facing surface of the cell membrane, confirming the inside-out growth pattern, and D2-40 immunohistochemistry confirmed lymphovascular invasion of carcinoma cells. Conclusion: We believe that the micropapillary pattern linked to higher frequencies of lymphovascular invasion and lymph nodal metastasis may be one of the most important invasive patterns in endometrioid carcinomas of the uterine corpus for predicting aggressive malignant potential, prognosis, and recurrence, although further, larger studies are required to evaluate its clinical significance.
Authors’ Response to Peer Reviews of “The Impact of SARS-CoV-2 Lineages (Variants) and COVID-19 Vaccination on the COVID-19 Epidemic in South Africa: Regression Study” (Preprint)
Authors: Mabuka Thabo , Naidoo Natalie , Ncube Nesisa , Yiga Thabo , Ross Michael , Kurehwa Kuzivakwashe , Nare Nyathi Mothabisi , Silaji Andrea , Ndemera Tinashe , Lemeke Tlaleng , Taiwo Ridwan , Macharia Willie , Sithole Mthokozisi
Published: July 2023

UNSTRUCTURED
The Effect of Explicit Suicide Language in Engagement With a Suicide Prevention Search Page Help-Seeking Prompt: Nonrandomized Trial (Preprint)
Authors: Onie Sandersan , Armstrong Susanne Oliver , Josifovski Natasha , Berlinquette Patrick , Livingstone Nicola , Holland Sarah , Finemore Coco , Gale Nyree , Elder Emma , Laggis George , Heffernan Cassandra , Theobald Adam , Torok Michelle , Shand Fiona , Larsen Mark
Published: July 2023

BACKGROUND

Given that signage, messaging, and advertisements (ads) are the gateway to many interventions in suicide prevention, it is important that we understand what type of messaging works best for whom.

OBJECTIVE

We investigated whether explicitly mentioning suicide increases engagement using internet ads by investigating engagement with campaigns with different categories of keywords searched, which may reflect different cognitive states.

METHODS

We ran a 2-arm study Australia-wide, with or without ads featuring explicit suicide wording. We analyzed whether there were differences in engagement for campaigns with explicit and nonexplicit ads for low-risk (distressed but not explicitly suicidal), high-risk (explicitly suicidal), and help-seeking for suicide keywords.

RESULTS

Our analyses revealed that having explicit wording has opposite effects, depending on the search terms used: explicit wording reduced the engagement rate for individuals searching for low-risk keywords but increased engagement for those using high-risk keywords.

CONCLUSIONS

The findings suggest that individuals who are aware of their suicidality respond better to campaigns that explicitly use the word “suicide.” We found that individuals who search for low-risk keywords also respond to explicit ads, suggesting that some individuals who are experiencing suicidality search for low-risk keywords.
Ankylosing spondylitis Is Associated With an Increased Risk of Inflammatory Bowel Diseases: Analysis of the United Kingdom Biobank (Preprint)
Authors: Su Yan -Bing , Dong Yi-Min , He Yuan , Ding Rong , Cheng Peng-Fei , He Xing-Xing , Ye Da-Wei , Wang Jin-Xi
Published: July 2023

BACKGROUND

Ankylosing spondylitis (AS) and inflammatory bowel diseases (IBDs) have been reported to correlated with each other in retrospective studies.

OBJECTIVE

Through a large sample size of Prospective cohort study to further support the relationship between Ankylosing spondylitis and Inflammatory bowel disease.

METHODS

The prospective associations between AS and Crohn’s disease(CD) or between AS and ulcerative colitis(UC) were analyzed with Cox regression models in prospective study cohorts, using data from the UK Biobank. We also calculated a polygenic risk score(PRS) for AS and analyzed its association with the risk of CD or UC. Finally, we used two-sample Mendelian randomization(MR) analyses to determine whether AS and IBDs have causal relationships on each other.

RESULTS

Participants with AS were at an over 7.8-fold risk of developing CD, and a 3.5-fold risk of CD. Reversely, the risk of AS in participants with CD(HR, 6.03; 95% CI, 3.10 ~ 11.73; P< 0.001) or with UC(HR, 3.08; 95% CI, 1.58 ~ 5.98; P< 0.001) were also greatly higher than the control population. These risks remained similar after adjusting for confounding factors in multivariate Cox models. Higher PRS of AS was also significantly association with increased risk of CD(HR, 3.60; 95% CI, 1.81~7.18; P<0.001) or UC(HR, 3.12; 95% CI, 1.92~5.08; P<0.001). In addition, the Mendelian analysis suggested a causal relationship of CD or UC on AS.

CONCLUSIONS

AS and IBDs are associated with greatly increased risk of developing each other in the individual level. This bidirectional risk correlation should be of clinical attention.
Otonomi Sosiologi Pedesaan di Asia Tenggara: Dari Ontologi Menuju Pengembangan Metodologi Riset
Authors: Sampean Sampean , Jannah Raudlatul
Published: July 2023

Artikel ini membahas tentang kajian Sosiologi Pedesaan di Asia Tenggara yang banyak dipengaruhi oleh pengetahuan Barat, meskipun karakteristik desa di Asia Tenggara berbeda dengan desa di Barat. Tujuan penelitian ini adalah untuk menganalisis ontologi Sosiologi Pedesaan di Asia Tenggara dengan menggunakan metode studi literatur pada tiga artikel yang diterbitkan pada tahun 1959 dan satu artikel tahun 2022. Penggunaan teori Pierre Bourdieu membantu peneliti menjelaskan praktik dominasi Barat terhadap kajian Sosiologi Pedesaan di Asia Tenggara. Penelitian ini menemukan bahwa sejarah perkembangan Sosiologi Pedesaan di Asia Tenggara tidak bisa dilepaskan dari orientalisme, kolonialisme, dan fenomena Perang Dunia II. Ilmuwan asing memainkan peran penting dalam memperkenalkan dominasi pengetahuan "ilmiah" Barat. Ontologi Sosiologi Pedesaan di Asia Tenggara diwarnai oleh tipe positivisme logis, tipe naturalistik, dan tipe materialisme. Penelitian ini menyimpulkan bahwa kajian Sosiologi Pedesaan di Asia Tenggara pada tahun 1959 dirancang untuk melayani kolonialisme dan kepentingan Barat, dan perlu adanya otonomi kajian Sosiologi Pedesaan yang memberikan  sudut pandang baru melalui pembaruan metodologi di Indonesia. Data Desa Presisi adalah salah satu bentuk pembaharuan metodologi dalam sistem penelitian di Indonesia yang berupaya membangun otonomi Sosiologi Pedesaan.
New Geopolitical Realities in the Armenian-Azerbaijani Confrontation and Prospects for the Development of Cooperation
Authors: Ismayilov Prof. Dr. Chingiz
Published: July 2023

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PHYTOCHEMICAL CONSTITUENTS AND ANTIOXIDANT ACTIVITY OF PERSEA AMERICANA LEAVE
Authors: OLASUNKANMI AMUDA MUTIU , OGUNYEMI ODERINLO
Published: July 2023

Objective: Persea americana is a popular plant that is well known for its fruit, which is highly consumed due to its nutritional and medicinal values. The rich secondary metabolites content of P. americana creates an opportunity to utilize it as a functional food or standardized herbal preparations. The quality of a medicinal plant is determined by the active substances produced by the plant. Therefore, the purpose of the present study is to determine the secondary metabolites present in P. americana grown in uncultivated farmland in Ogbomoso, Oyo State Nigeria.
Methods: The dried pulvurised leaves of P. americana from uncultivated farmland in Ogbomoso, Oyo State Nigeria were extracted with methanol by the maceration method and partitioned successively with solvents of increasing polarity. The extracts obtained were subjected to phytochemical screening and the total phenolics were determined spectrometrically using the folin–ciocalteu method.
Results: The phytochemical screening showed that P. americana is rich in various secondary metabolites such as flavonoids, saponins, tannins, and alkaloids. The total phenolic content gave 500µg/g gallic acid equivalent. The total flavonoid content obtained was 250µg/g using quercetin as standard. The anti-oxidant assay of the crude extract showed a high activity of 89.05% at a concentration of 0.05g/ml.
Conclusion: Total phenolic content of the plant is likely to be a key for determining the free radical scavenging and ROS reducing ability of the plant.
Idiomaticidade na gramática: um estudo da Construção Bem Que S
Authors: Sousa Clara , Pinheiro Diogo
Published: July 2023

No PB, há uma construção idiomática particular identificada pela sequência “bem que”. Exemplos do seu uso são frases como “Bem que minha mãe avisou que ia chover” e “Bem que eu queria ganhar na loteria”. A proposta desse trabalho é  investigar esse fenômeno sob a luz da Gramática de Construções Baseada no Uso (BYBEE, 2010; GOLDBERG, 2006). Adotando essa perspectiva, propomos que todos os usos analisados da sequência “bem que” são instâncias de uma construção mais abstrata, a Construção de Bem Que S. Especificamente, neste artigo, propomos que ela é identificada, formalmente, pela sequência [bem que [sentença]] e, no polo semântico-pragmático, pela presença do valor de rejeição de proposição. Nesse sentido, defendemos que trata-se de uma construção de intersubjetividade, já que atua no gerenciamento de informações inter-sujeito. Aqui, a partir de uma análise qualitativo-interpretativa de dados retirados do Twitter, procuramos relacionar, detalhadamente, os usos dessa construção com as generalizações propostas.
Multimodalidade e as estruturas desgarradas em anúncios publicitários: uma estratégia para favorecer a sedução
Authors: Campos Rosane Cassia Santos e
Published: July 2023

Este trabalho investiga, em anúncios publicitários, o uso das estruturas desgarradas, assim denominadas por Decat (2004, 2011). Segundo Decat (2004, 2011), o ‘desgarramento’, seja de SNs ou de orações, se apresentaria como maneira de marcar a importância de tal constituinte para uma estrutura informacional. Para a presente análise foram selecionados cinco anúncios publicitários, produzidos em língua portuguesa e veiculados em mídia de circulação nacional. Parte-se da hipótese de que anúncios publicitários constituem um gênero textual legítimo, com características e com especificidades exigidas para a sua produção que as estruturas desgarradas estariam a serviço da evidencialização do que esses anúncios propõem. Nesse sentido, é de grande relevância apresentar as quatro metafunções propostas por Halliday (1989) para que seja possível considerar anúncios como produções multimodais e, desta maneira, discorrer sobre os postulados defendidos pela Teoria da Multimodalidade, nos termos da Gramática do Design Visual tal como desenvolvida por Kress e Van Leeuwen (2006), considerando o texto em seus aspectos visual e verbal, partindo do princípio de que o visual e outros modos semióticos seguem determinados propósitos comunicativos. Ao fim, conclui-se que as estruturas desgarradas, associadas aos elementos da multimodalidade, representam um importante constituinte dos anúncios para que a valorização do produto seja evidenciada. As estruturas desgarradas têm a forte função de salientar informações com grande relevância para que se efetive o consumo de uma ideia ou de um produto, ou seja, conclui-se que a informação, em um anúncio publicitário, pode ganhar um destaque que não teria se não estivesse ‘desgarrada’.
A expressão de desejos em construções condicionais insubordinadas com “se ao menos”
Authors: Bernardo Comarim Maria Julia , Bezerra de Menezes Hirata Vale Flávia
Published: July 2023

As construções insubordinadas são, segundo Evans (2007), aquelas que apresentam marcas de subordinação, mas ocorrem de maneira sintática, semântica e pragmaticamente independente. As construções condicionais insubordinadas (CCI) têm um uso específico, conforme Hirata-Vale (2015), porque veiculam valores pragmáticos específicos, como a expressão de desejos. Neste artigo, analisam-se qualitativamente as CCI encabeçadas pelo “se ao menos”, coletadas no Corpus do Português. Para tanto, a análise se vale dos parâmetros de condicionalidade de Dancygier (1998) e da classificação funcional de D’Hertefelt (2015) desse tipo de construção nas línguas germânicas. Nas CCI com “se ao menos”, apenas os parâmetros não-assertividade e criação de espaços mentais hipotéticos são mantidos. Nessas construções, emerge o valor de desejo, formalmente marcado pelo imperfeito do subjuntivo. Conclui-se que há uma especialização das CCI encabeçadas pelo “se ao menos” para a expressão de um valor semântico específico de desejo que, embora esteja relacionado à condicionalidade, por se localizar no domínio do hipotético, dela se diferencia, conforme a categorização proposta por D’Hertefelt (2015).
Estrutura retórica, combinação de orações, estruturas desgarradas: revisitando contribuições de Beatriz Decat para estudos funcionalistas
Authors: Coneglian Andre Vinicius Lopes , Desiderato Antonio Juliano
Published: July 2023

Este trabalho tem como objetivo destacar as importantes contribuições de Maria Beatriz Nascimento Decat para a investigação do tradicional “período composto”. No Brasil, Decat foi a pioneira nos estudos da estrutura relacional discursiva a partir da Teoria da Estrutura Retórica. À luz de alguns dos principais trabalhos de Decat, analisamos dois corpora, um de língua falada constituído de entrevistas de professores universitários, e outro de língua escrita, constituído de uma amostra de crônicas, a fim de descrever o funcionamento de relações discursivas e combinação de orações, bem como das construções desgarradas, respectivamente. Os dados de língua falada mostram alto índice de ocorrência da conjunção temporal quando e baixo índice de ocorrência de outras expressões de natureza temporal, como na hora em que ou depois que. Os dados de língua escrita revelam alta frequência de ocorrência de desgarramento de constituintes de predicação simples e baixa frequência de ocorrência de desgarramento de predicados complexos. Esses dois estudos permitem tanto confirmar algumas das teses defendidas por Decat, quanto propor novas generalizações com base nos dados apresentados, particularmente no que diz respeito à testagem quantitativa de propostas feitas pela homenageada em seus trabalhos.
Uma proposta preliminar de descrição fonética e análise fonológica das consoantes da língua biafada/Guiné-Bissau
Authors: Lopes Mário Alexandre Garcia
Published: July 2023

A proposta deste artigo é apresentar uma descrição fonética das consoantes do biafada e algumas reflexões sobre a organização silábica dessa língua. A língua biafada é falada por 29.500 pessoas em Guiné-Bissau, país localizado no oeste africano, em quatro dialetos, a saber: binala, bubwas, cacandé e buwol. O biafada pertence ao tronco linguístico nigero-congolês e integra a família oeste-atlântica no grupo norte. Dentre outros, destacam-se quatro estudos da tipologia linguística sobre a língua biafada: Koelle (1854), Klingenheben (1924) e Wilson (1984, 1993). No entanto, não foram feitas, ainda, descrições e análises nas áreas de fonética e fonologia para essa língua. Neste trabalho, desenvolvemos uma metodologia caracterizada, primeiramente, pela observação etnográfica, segundo, pela aquisição da língua feita através de aulas e de um encontro de escrita da língua biafada. Através dessas atividades, transcrevemos, com base no Alfabeto Fonético Internacional, 1.600 palavras e frases desta língua. Por fim, a metodologia focalizou a descrição e a análise dos sons/fones consonantais. Eles foram classificados e identificados de acordo com o modo e o ponto de articulação. Também verificamos os padrões silábicos, observando a ocorrência das consoantes nas estruturas silábicas de ataque, núcleo e coda.
Análise do conector [atrás de] – uma visão funcional centrada no uso
Authors: Do Rosário Ivo Da Costa , Machado Marcello Martins
Published: July 2023

Este trabalho tem como objetivo analisar e descrever os usos do conector [atrás de] na função de articulador de orações em língua portuguesa. A coleta de dados sincrônicos foi feita no Corpus do Português. Emprega-se uma metodologia mista (LACERDA, 2016), que mescla a análise de dados em viés quantitativo e qualitativo. O arcabouço teórico adotado é o da Linguística Funcional Centrada no Uso (LFCU), nos termos de Furtado da Cunha, Bispo e Silva (2013) e Rosário e Oliveira (2016), sob a compreensão de que o elemento fundante da gramática é a construção, ou seja, um pareamento simbólico de forma e sentido (GOLDBERG, 1995; CROFT, 2001). O trabalho também mobiliza outros conceitos de base cognitivo-funcional, como categorização e chunking (cf. BYBEE, 2010; 2016), neoanálise e analogização (cf. TRAUGOTT; TROUSDALE, 2013), subjetividade (cf. TRAUGOTT; DASHER, 2002), além de outros associados à articulação de orações no plano funcional (LEHMANN, 1988; MATTHIESSEN; THOMPSON, 1988; GIVÓN, 1990; HOPPER; TRAUGOTT, 1993; NEVES, 2001; BRAGA, 2001). Com base em uma amostra de 100 ocorrências de [atrás de], foram encontrados 10 dados na função de articulador de orações. Esse conector, híbrido por natureza, combina orações com características de complementação circunstancial e de hipotaxe de finalidade.
A Review Paper on Bacterial Self-Healing Concrete
Authors: Sharma Vaidik , Singi Prof. Mayur
Published: July 2023

Abstract: Bacterial self-healing concrete (BSHC) has emerged as a promising technology in the field of construction materials due to its ability to autonomously repair cracks and enhance the durability and service life of concrete structures. This paper presents a comprehensive review of the existing literature on the strength properties of bacterial self-healing concrete. The objective of this review is to provide an overview of the research conducted in this area, assess the effectiveness of bacterial selfhealing in improving the mechanical properties of concrete, and identify potential areas for future research.
Scientific writing: A way to improve students' information literacy and reasoning ability
Authors: Permana Tutut Indria , Fatmawati Diani , Nuryady Moh. Mirza , Fahlevy Ikmal Reza , Ardiansyah Ivan
Published: July 2023

The abilities students need to fulfill the SDGs are current information literacy and reasoning skills. Apart from going through the learning process, this ability can be developed by the participation of students in extracurricular activities related to scientific writing. This service activity aims to provide scientific writing assistance for students at Batu Islam High School to improve information literacy and reasoning skills. The form of training carried out is to provide material related to various research that can be carried out by students both inside and outside the classroom and provide assistance to take part in scientific writing competitions at the national level. The instruments for community service activities used are information literacy questions and observation sheets. Data analysis was carried out descriptively. The results of community service activities show that there is an increase in students' information literacy and reasoning abilities. The results of the participation of students in the national competition won the third prize
From waste to wealth: A novel approach for empowering society through recycling used cooking oil into soap
Authors: Mahmudah Rif'atul , Shofiah Nurul
Published: July 2023

Soap made from waste cooking oil can be a potential product that can be developed to improve the economy and as an effort to preserve the environment by utilizing household waste. Waste cooking oil can be reprocessed into soap-based ingredients through an oil purification system so that the color is clear and does not smell rancid by using bagasse and orange peel adsorbents in the bleaching process. This service aims to train students' understanding of Mambaul Hikam Islamic boarding school about processing solid and liquid soap from waste cooking oil through the cold process method and the hot process method. The results of the service show firstly, the transfer of knowledge, skills, and affection for making liquid and solid soap using cold and hot process techniques through appropriate technology. Second, the formation of a community of students who can become facilitators in assisting the manufacture of laundry soap from used cooking oil waste. Soap production from this assistance is still an internal use of the Islamic boarding school but the students are expected to be able to increase the production of soap which can improve the economy of the santri and the Mambaul Hikam Islamic boarding school.
THE GEOPOLITICAL FACTOR OF THE DEVELOPMENT OF SWISS MILITARISM IN THE CONTEXT OF MILITARY ENTREPRENEURSHIP OF THE XIV-XVI CENTURIES
Authors:   Irkutsk State University (Russia), Lakhtyuk S.A. , Kostrov A.V. ,   Irkutsk State University (Russia), Saitgareev R.R. ,   Irkutsk State University (Russia)
Published: July 2023

The article discusses the possibilities and factors of influence of natural space on the formation of a special attitude of the population to the phenomenon of war. As an example, Switzerland is considered in the period of its formation within its modern borders in the XIV-XVI centuries. Separately, the authors note the understanding of the phenomenon of militarism as a sociocultural construct by the authors, including based on the originality of this approach in modern Russian historiography. Geographic determinism is used as the main research method. On its basis, using the data given in synchronous written sources, the influence of mountainous rugged terrain on the population's perception of the phenomenon of war and the formation of militarism in the socio-cultural space of society is considered. There is a difference in attitudes towards military affairs in the mountainous cantons of Switzerland and the plains. The researchers point out that this fact is most clearly seen in the Kappel religious wars, where the mountain cantons, in addition to protecting religious beliefs, defended their right to military enterprise, while reformers from the flat part of the country considered mercenarism as a threat to the unity of the country. In conclusion, a conclusion is made about the direct influence of the natural-geographical factor on the perception of the surrounding space and, as a result, the special attitude of the population in military affairs i.e., formation of the socio-cultural phenomenon of militarism.
FBI VS. AFRICAN AMERICANS (BASED ON COINTELPRO PROGRAM DOCUMENTS)
Authors:   The Autonomous non-profit organization Research Center «Institute of World Politics and Economics» (Russia), Zakirov A.V.
Published: July 2023

Today we are witnessing how various US intelligence agencies are engaged in espionage activities around the world. However, US citizens have been subjected to the most sophisticated methods of persecution in history. Using the example of the FBI's COINTELPRO program (carried out from 1956 to 1971), directed against activists of the African-American civil rights movement, the article examines the FBI's activities to protect the socio-political foundations of American society, which cannot be called anything but segregational and racist. The author showed how the US government influenced key figures of the civil rights movement in the USA, such as Martin Luther King Jr., Malcolm X and activists of the Black Panthers party through the FBI COINTELPRO program. The consequences of the program are considered, including restrictions on civil liberties, trust in the government and institutional violation of the rights of African Americans. The relationship between the latter phenomenon and earlier phenomena of discrimination against the rights of the "Colored People" of the United States, such as abolitionism and segregation, is carried out. The article analyzes the impact of the FBI's COINTELPRO program on modern times, including its reflection on modern legal norms, counterintelligence measures and public opinion about government surveillance. The study of the FBI's COINTELPRO program is important for understanding the complex relationship between government and civil society.
COMPARATIVE ANALYSIS OF THE TRAJECTORIES OF ONE-COURTYARD PEOPLE SETTLEMENT IN PUTIVL AND OREL COUNTIES
Authors:   the Kursk branch of the ROIA (Russia), Kudlanov K.B. , Golubkov R.O. ,   the Kursk historical genealogical society (Russia)
Published: July 2023

The study is based on the analysis of previously unpublished sources of RGADA, and other narrative sources. In the article researchers from the middle of XVI-th century compared the places of exit of settlers at two service cities that were situated on the Tula defensive system: Oryol and Putivl. In the course of the study, the authors, distributing the exit points of all the service military classes of Putivl and Orel along the trajectories of settlement, established similarities and differences between them. The main difference was that these two counties were located on different river systems (Orel on the Okskaya river system, and Putivl – on the tributaries of the Desna River). This difference imposed its own characteristics on 4 common features between these counties, which the authors identified. The similarity consisted, firstly, in the predominance of the northern Great Russian migration flow. True, it flowed to Oryol from the cities of the Tula defensive line, and to Putivl – from places outside of Moscow. Secondly, in a strong neighborhood trajectory of settlement. Only in Orel it flowed from the advanced cities of the Tula defensive system, and in Putivl – from the northern cities. Thirdly, in the presence of the local population, the descendants of the vyatichi in Orel, and the sevryuki in Putivl. However, given that the last city did not cease to exist, the concentration of the local population within its county was stronger. The main similarity of the studied counties consisted in the methods of settlement, because both in Putivl and in Orel there were all 3 categories of service migrants: unauthorized migrants, resettled people in military service and the local population. As a result, the authors conclude that in Putivl and Orel districts the northern and local trajectories of settlement were the main ones, with the absolute dominance of the first, and the rest were auxiliary. Thus, the slight difference in the geolocation of the studied counties did not cancel the similarity of the general methods and features of the settlement of these areas from the middle of XVI century.
Characteristics of Vitamin D3 Receptor Genotypes in T2DM of Iraqi Obese Women
Authors: Mutar Baraa Abdul-Kareem , Allwsh Thikra Ali , Yassin Ammar Gany , Al-Tu’ma Fadhil Jawad , Taghi Hassanien S.
Published: July 2023

Objective: This study aims to examine the association between the (rs1544410) polymorphism of the VDR gene with the pathogenesis of T2DM in Iraqi obese women.

Methods: A case-control study was performed on 50 patients with T2DM and 50 apparently healthy subjects who were admitted to Al-Hussein Teaching Hospital and Al-Hassan Center of Diabetes and Endocrinology unit / Kerbala health directorate – Iraq during (April 2022 – March 2023). The T2DM groups were divided into two groups, 25 obese and 25 non-obese; the control group was divided into 25 obese and 25 non-obese as apparently healthy groups. The ELISA Kit was used to measure serum 25(OH)D3, heat shock protein-70, VDBP, insulin and C-peptide. Also HbA1c% and insulin resistance (HOMA-IR) were evaluated. The vitamin D3 receptor gene (VDR) variant and the SNP (rs1544410) polymorphism was determined using allele specific polymerase chain reaction, 1.5% agarose gel electrophoresis and then visualized by gel photo-documentation system.

Results: The result of vitamin D3 variants genotype (rs 1544410) was a clear band with a molecular size of 200 bps. The size of the amplicon was determined by compare with DNA ladder 100 - 1500 bp. The result of the comparison between observed and anticipated values for SNIP with (rs 1544410) in the tested population was statistically significant, P= < 0.001 and the difference between demographic characteristics and (rs 1544410) SNP, age and BMI shows non-significant difference among all groups. The difference between biomarkers and (rs1544410) SNP was performed using one-way ANOVA test to compare the mean levels of HSP-70, VDBP, C-peptide,  RBC and HbA1c% which shown a non-significant difference among the variants of VDBP Genotype (rs1544410) in  obese women (patients and control) studied groups, p value > 0.05.  

Conclusion: The logistic analysis of the (rs1544410) SNP of the patients concluded that HSP-70, VDBP, and C-peptide  level was no significantly related to the also C-peptide, was shown to be a related risk factor to both CT and CT alleles (1.003, p > 0.05) in comparison with CC alleles. Furthermore, HbA1c% level was demonstrated to be related as a risk factor for the CG allele in comparison with CC and GG alleles (1.009, p < 0.05).
Integration of Migrants Through the Lens of a Constructivist Approach to Ethnicity
Authors: Varshaver Evgeni A.
Published: July 2023

The article rethinks the integration of migrants through the lens of constructivist studies of ethnicity. It is done on the basis of the theoretical language developed by the author, which builds upon other constructivist languages. It is pointed out that ethnicity is the organization of differences around categories, membership in which is predominantly inherited. Categories, according to language, are organized in the form of categorizations, classifications, and taxonomies; categories are associated with attributes, which include stereotypes, indicators, norms, characteristics of relationships with other categories, as well as discourses. Together, categories and attributes form the construction of ethnicity, which is a typical object of analysis and description. Individuals constantly evaluate the surrounding phenomena in terms of conformity with the construction of ethnicity, which is why the construction of ethnicity changes. Integration is a change in the construction of ethnicity or re-categorization of individuals in the space of the dichotomy «migrant» - «local» without changing the construction of ethnicity. In the course of integration, «migrant» categories may be re-categorized as «local»; «local» categories may change the attributes associated with them to include attributes previously associated with «migrant» categories; categories and attributes may not change, while re-categorization occurs at the individual level. How exactly integration will take place depends on a variety of factors that characterize the construction of ethnicity and go beyond it. The construction of ethnicity in Russia is a vernacular taxonomy, which implies the existence of a general category (‘Rossijane’, ‘Russkie’), which includes other categories - defined as the «local» ones. Most of the «migrant» categories correspond to identical in name «local» categories. The integration of migrants in Russia thus takes the form of an individual transition from the category of «Tajik migrants» to «local Tajiks». The language created and studied for applicability to the integration of migrants is analyzed for pros and cons and directions for further work are identified.
Dervish Mehmed bin Mubarek Geray Genghisi. The Chronicle “Tarikh-i Mehmed Geray” (“Mehmed Giray’s History”). Part 3
Authors:   Fevzi Yakubov Crimean Engineering and Pedagogical University, Abduzhemilev Refat R. ,   Marjani Institute of History of the Tatarstan Academy of Sciences
Published: July 2023

The Chronicle “Tarikh-i Mehmed Geray” (1682–1703) by the Crimean Tatar historiographer Dervish Mehmed bin Mubarek Geray Genghisi is the narrative source reflecting the history of the Crimean Khanate and the Ottoman state in 1682–1703. The date of the work is 1703 (completed in the month of Rejeb 1115). A copy of the chronicle has been preserved in the funds of the Austrian National Library (Österreichische Nationalbibliothek) under the cipher (inventory number) No. 1080, Cod. H.O.86 HAN MAG. Volume (folio) – 125 sheets in taalik script, sheets are small. There are verses on 125 sheets. The manuscript is not marked with the title, but has an appraisal prescript: “Tarih-i Mehmed Geray Qara Mustafa Paşa cenklerin söyler üçünci Sultan Mehmed Han vaqtlarından Sultan Ahmed Han biñ yüz on beş tarihınacek söyler bir maqbul tarihdır” / “Mehmed Tarikh-i Mehmed Giray narrating about the wars of Kara Mustafa Pasha, the acceptable story telling from the time of Sultan Mehmed Khan III to the period of Sultan Ahmed Khan, up to the year one thousand one hundred and fifteen”. The Chronicle’s translation into Russian (the author of the translation is R.R. Abduzhemilev) was made from the text’s transliteration of the manuscript into Latin, presented in the Turkish edition of Ugur Demir’s master thesis “Tarikh-i Mehmed Giray” (assessment – text’s transcription)” (consultant: Prof. Dr. Nejdet Öztürk, Istanbul, 2006, 163 pages).
Crimean Tatars in the national-state constructionof the Crimean ASSR (20–30s of the 20th century)
Authors:   Fevzi Yakubov Crimean Engineering and Pedagogical University, Kondratjuk Grigorii N. ,   Marjani Institute of History of the Tatarstan Academy of Sciences
Published: July 2023

The article analyzes the processes of national-state building in the Crimean ASSR in the interwar period. It is noted that the beginning of the 1920s was characterized by a wide inclusion of the representatives of the Crimean Tatar national movement in the creation of the authorities of the republic. The creation of the Crimean ASSR became the Soviet version of the state building processes of the Crimean Tatars.
Fūdo in Foreign Language Learning in Japan and Finland
Authors: Nishimura-Sahi Oshie
Published: July 2023

While the Japanese education system and policy have been studied extensively, Japanese philosophy and thoughts have rarely served as a theoretical and methodological resource in the field of comparative and international education. Resonating with a current scholarly attempt to explore the possibilities and limitations of using Japan as an epistemic resource, I have experimented with drawing upon Japanese philosophical thinking, namely Watsuji Tetsurō’s (1889-1960) comparative phenomenological study, to analyse the current foreign language education reforms in Japan. In this paper, I tell the story of my thought experiment in which I explore autoethnographically how my epistemic mindset has changed during my PhD journey through a slow dialogue with Watsuji’s study on milieu, relationality and ontological inquiry into human beings. Aiming to multiply the epistemological resources for educational research, I analyse reflexively on the way in which I was destabilised by Japanese philosophy in (un)learning educational practices in Japanese contexts. In so doing, I explore how ‘foreign’ educational comparativists might be able to move beyond the storyteller role in foreign contexts or the expert role in home contexts and, accordingly, contribute to promoting a pluralistic knowledge production.