bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of flunixin meglumine, meloxicam, and firocoxib on the acute-phase proteins in horses following standing castration
Authors: Filippo Paula A. Di , Gobbi Francielli P. , Lemos Gabriela B. , Quirino Célia R. , Martins Carla B. , Fonseca Leandro A.
Published: July 2021

ABSTRACT: Excessive infection and inflammation are the most common complications associated with castration. The objective of this study was to compare the efficacy of flunixin meglumine (FM), meloxicam (MX), or firocoxib (FX) for inflammation control after castration in horses using acute-phase proteins (APP) as markers of inflammation. Thirty healthy, unbroken, mixed-breed horses (body weight 358.62±45.57kg and age 4.99±2.63 years) were randomly (n=10 animals/group) allocated to receive one of three different post-castration anti-inflammatory medicines: Group 1 (FM 1.1mg/kg bwt, IV, s.i.d for 5 days); Group 2 (MX 0.6mg/kg bwt, IV, s.i.d for 5 days); and Group 3 (FX 0.1mg/kg bwt, IV, s.i.d for 5 days). All horses were castrated in standing position, using the open technique. Serum and peritoneal APP concentrations were measured by sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis (PAGE) and determined before castration (0), and 3, 5, 24, 48, 72, 120 and 168 hours after castration. The results were submitted to analysis of variance using the SAS statistical program, and means were compared by the Student-Newman-Keuls test (p<0.05). Three animals from the MX group developed hyperthermia (with rectal temperatures of 39.8, 39.3 and 38.9°C on day 4, 5 and 6, respectively) and showed local clinical signs of inflammation (inguinal and excessive scrotal edema) and reluctance to walk, as well as a rigid gait of the hind limbs. The same complications were observed in one FX horse. No complications were observed among the FM animals. The castration resulted in significant changes in serum and peritoneal values of total proteins, ceruloplasmin (Cp), transferrin (Tf), albumin (Alb), haptoglobin (Hp) and α1-acid glycoprotein (Gp) in animals of all experimental groups. However, the animals of the MX and FX groups presented more intense acute phase response compared to the animals of the FM group. Changes in the APP were associated with the surgical trauma of castration, but the differences between groups were associated with the ability of the nonsteroidal anti-inflammatory drug to control the inflammation. In conclusion, and based on the findings of acute phase proteins, flunixin is more efficient to control the magnitude of inflammation following castration as compared to meloxicam and firocoxib.
Stx1 and Stx2 subtyping and antimicrobial resistance in Shiga toxin-producing Escherichia coli (STEC) isolates from cattle and sheep feces in the Southeastern region of the State of Goiás, Brazil
Authors: Arrais Bruna R. , Silveira Ângela V.B.A. , Oliveira Angélica F. , Barbosa Nayara C. , Stella Ariel E. , Alves Benner G. , Ferreira Marcos R.A. , Moreira Cecília N.
Published: July 2021

ABSTRACT: The present study was aimed at subtyping of Stx1 and Stx2 genes and characterization of antimicrobial resistance in 106 Shiga toxin-producing Escherichia coli (STEC) strains isolated from cattle and sheep feces. PCR was used to determine the subtypes, and the disk-diffusion method was used to evaluate the antimicrobial resistance. Ten antibiotics from five different classes were tested. Among the isolates of bovine origin, two subtypes of Stx1 (Stx1a and Stx1c), and four subtypes of Stx2 (Stx2a, Stx2b, Stx2c, and Stx2d) were identified. In isolates of sheep origin, two subtypes of Stx1 (Stx1a and Stx1c), and four subtypes of Stx2 (Stx2a, Stx2b, Stx2c, and Stx2 g) were identified. The results obtained suggest the presence of high diversity in Stx1 and Stx2 genes. Further, 96.6% (57/59) of bovine fecal strains and 89.4% (42/47) of sheep fecal strains showed resistance to at least one tested antibiotic. In both animal species, most strains were multidrug-resistant (MDR) (67.8% in cattle and 59.6% in sheep), with no significant difference between host animals. Adult animals were eight times more likely to have STEC with greater pathogenic potential. STEC with the highest pathogenic potential were three times more likely to be multidrug-resistant than STEC with the lowest pathogenic potential. The data reported in this study suggests the occurrence of strains with high potential pathogenicity in the region studied. Therefore, the ruminants of this region are carriers of strains that can cause infections in humans.
Spontaneous poisoning by Cestrum intermedium in dairy cattle
Authors: Pohl Camila B. , Hammerschmitt Márcia E. , Molossi Franciéli A. , Lorenzett Marina P. , Bianchi Ronaldo M. , Vignoli-Silva Márcia , Bianchetti Samuel , Panziera Welden , Barros Claudio S.L. , Pavarini Saulo P. , Driemeier David
Published: July 2021

ABSTRACT: Acute hepatotoxicity caused by plants poisoning is responsible for economic losses in farm animals in Brazil. Reports of Cestrum intermedium natural poisoning in cattle are not commonly described in Rio Grande do Sul (RS). This study aimed to document an outbreak of spontaneous C. intermedium poisoning in dairy cattle in the Central-Eastern Mesoregion of RS. Three nine-month-old Holstein and Jersey heifers were affected after they were placed in a small paddock with shortage forage. In this area, specimens of C. intermedium Sendtn with signs of consumption were observed. Morbidity and lethality rates were 100% and clinical courses ranged from 9 to 12 hours. At post mortem examination of the three heifers, there was predominance of acute liver lesions. The liver was moderately enlarged and on the cut surface there was a marked accentuation of the lobular pattern and hemorrhage. Inside the rumen, partially digested C. intermedium Sendtn leaves were observed. The histological aspects of the liver were mostly centrilobular coagulative necrosis and hemorrhage, frequently extended to the midzonal region. The immunohistochemistry technique was performed, in which the polyclonal antibody caspase 3 was used in liver fragments. Moderate to marked immunolabeling was observed in the cytoplasm and nucleus of hepatocytes, predominantly on the periphery of areas of hepatic necrosis indicating cell apoptosis. The diagnosis of C. intermedium Sendtn poisoning in dairy cattle in this study was based on epidemiological, clinical and anatomopathological findings. Since the C. intermedium poisoning is uncommon in dairy cattle, we are describing it for the first time in the Central-Eastern Mesoregion of RS, and represents a differential diagnosis of other acute toxic liver diseases in cattle.
NEUROPSYCHOMOTOR DEVELOPMENT IN CHILDREN AND ADOLESCENTS WITH LIVER DISEASES: SYSTEMATIC REVIEW WITH META-ANALYSIS
Authors: SANTOS Juliana Costa , SAQUETTO Micheli Bernardone , GOMES NETO Mansueto , SANTOS Josiane de Lima dos , SILVA Luciana Rodrigues
Published: July 2021

ABSTRACT BACKGROUND: The nature of liver disease, the evolutionary course and duration of liver diseases, as well as the degree of severity and disability can trigger multiple outcomes with repercussions on neuromotor acquisition and development. OBJECTIVE: To systematically review and conduct a meta-analysis to evaluate the effects of liver disease on the neuropsychomotor development of children and adolescents with their native livers and those who underwent liver transplantation. METHODS: Observational studies published since the early 1980s until June 2019 were sought in the PubMed and Scopus databases. An α value of 0.05 was considered significant. The statistical heterogeneity of the treatment effect between the studies was assessed by the Cochran’s Q test and the I2 inconsistency test, in which values above 25 and 50% were considered indicative of moderate and high heterogeneity, respectively. Analyses were performed with Review Manager 5.3. RESULTS: Twenty-five studies met the eligibility criteria, including 909 children and adolescents with liver disease. Meta-analyses showed deficits in total IQ -0.41 (95%CI: -0.51 to -0.32; N: 9,973), verbal IQ -0.38 (95%CI: -0.57 to -0.18; N: 10,284) and receptive language -0.85 (95%CI: -1.16 to -0.53; N: 921) in liver transplantation, and those with native livers who had symptoms early had total and verbal IQ scores (85±8.8; 86.3±10.6 respectively) lower than the scores of those with late manifestations (99.5±13.8; 96.2±9.2). Gross motor skill was reduced -46.29 (95%CI: -81.55 to -11.03; N: 3,746). CONCLUSION: Acute or chronic liver disease can cause declines in cognitive, motor and language functions. Although the scores improve after liver transplantation, children remain below average when compared to healthy children.
Productivity and quality of sweet potato roots propagated by mini-cuttings with different trays and seedling ages
Authors: Cardoso Antonio Ismael Inácio , Nasser Maurício D , Nakada-Freitas Pâmela G , Vieites Rogério L , Martins Bruno NM , Ramos Juliana A , Furlaneto Karina Aparecida , Rós Amarilis B
Published: July 2021

ABSTRACT The use of mini-cuttings is an option for obtaining sweet potato propagules of excellent quality. The objective of this research was to evaluate the production and quality of sweet potato roots propagated by mini-cuttings in different types of trays and ages of seedlings. Six treatments, resulting from the factorial 2x3, were evaluated: two types of trays (162 and 200 cells, with 31 and 18 mL of substrate per cell, respectively) and three ages of seedlings (39, 46 and 53 days after placement of mini-cuttings in trays), in a randomized block design, with five replications. Seedlings characteristics, production and quality of roots were evaluated. Higher number and dry weight of leaves per seedling were observed in the tray with 162 cells than in trays with 200 cells. The younger seedlings (39 days) had a lower number of leaves, dry weight of leaves, stem, roots ant total (leaves + stem + roots) than seedlings of other ages. There was no difference in root production depending on the type of tray, regardless of the age of the seedlings. For the 162-cell tray, the age of the seedlings did not affect the production of roots. On the other hand, for the 200-cell tray, higher roots production was observed on seedlings 39 days age compared to seedlings with 53 days. No differences were observed among the roots of different treatments for titratable acidity, and levels of sucrose, reducing sugars ant total sugars. It is recommended to avoid old seedlings, that is, it is recommended to use seedlings with a maximum of 43 days after planting of mini-cuttings for trays with 200 cells, while for trays with 162 cells no difference in root production was observed with the different ages of the seedlings.
Morpho-agronomic characterization and genetic divergence in lentil genotypes
Authors: Cardoso Fabiana R , Brasileiro Lemerson de O , Ragassi Carlos Francisco , Carvalho Agnaldo DF de , Silva Patrícia P da , Vieira Jairo V , Nascimento Warley Marcos
Published: July 2021

ABSTRACT Lentil production has been increasing in Brazil, due to strong national and international demand. Despite the economic importance, few cultivars are available on the Brazilian market. The aim of this study was to evaluate 48 lentil inbred lines and one commercial cultivar (Silvina), based on morpho-agronomic traits and to identify genotypes which can be used in a plant breeding program. Twenty-one morpho-agronomic descriptors (nine qualitative and twelve quantitative) were used. The descriptors showed genetic variability among the genotypes. Clustering techniques using characterization data allowed to identify genetically divergent genotypes as well as identify superior genotypes in relation to agronomic traits: FLIP2010-8L and FLIP2010-12L (similarity group I), FLIP2010-99L, FLIP2010-20L and FLIP2010-106L (group II), FLIP90-25L and 6031 (group III), FLIP2007-16L (group IV) and the commercial cultivar Silvina (group V). We concluded that these genotypes have the potential to be used in lentil breeding programs.
Agronomic performance of experimental super sweet corn hybrids
Authors: Gava Emanuel , Faria Marcos V , Zaluski Welton L , Rosa Jocimar C , Paiva Elida AP , Chiquito Nathany R
Published: July 2021

ABSTRACT Super sweet is classified as a special type of corn, due to the presence of genes which promote sugar accumulation in grains, significantly reducing starch content in the endosperm. This study aimed to evaluate the agronomic performance of experimental super sweet corn hybrids, carrying the gene shrunken-2, in order to identify and select promising genotypes for Southern Brazil. The experiments were carried out in two sowing seasons in 2017/18, in the experimental field of UNICENTRO, Guarapuava-PR, Brazil. Thirty-two experimental hybrids resulting from an 8x4 partial diallel among super sweet corn inbred lines from four distinct populations were evaluated along with two commercial hybrids (BRS Vivi and Tropical Plus) used as checks. Traits of agronomic and commercial interest were evaluated: male flowering (MF), husk covering index (HCI), yield of husked ears (YHE), grain yield (GY), commercial prolificacy (CPR), percentage of commercial ears (PCE), color (COL) and soluble solids (SS) of the grains. We verified significant differences among the experimental hybrids, except for COL. There was no significant effect of sowing season regarding to SS. Genotypes x seasons interaction was significant for YHE, GY, CPR, PCE and COL. There are promising experimental hybrids showing performances superior to commercial super sweet corn hybrids used in Brazil. The experimental hybrids D2-61 x D5-41 and D3-10 x D5-43 were superior to the other experimental genotypes. The experimental hybrid D2-61 x D5-41 shows potential to meet the demands of the current super sweet corn market.
RETRATO DAS NARRATIVAS DE MAES UNIVERSITARIAS NO CONTEXTO ACADÊMICO
Authors: Silva Elenir Lindaura da , Benitez Priscila , Mizael Táhcita Medrado , Pasian Mara Silvia
Published: July 2021

Questões relacionadas ao gênero, especificamente, sobre o fator maternidade, têm sido documentadas como desafios importantes para serem superados no ambiente acadêmico e precisam ser investigados para que possa ocorrer uma melhor compreensão que gerem possibilidades de apoio e condições favoráveis para o pleno desenvolvimento da formação acadêmica com condições igualitárias. O trabalho teve como objetivo refletir sobre o espaço de mães na universidade pública brasileira, enquanto protagonistas do seu processo educacional, possibilitando assim, a construção de possíveis fatores de proteção que garantam a permanência das mesmas na universidade e em equidade aos demais estudantes. Para a construção do trabalho foi realizada uma revisão de literatura com temática relativa a maternidade na educação superior com enfoque nas diferenças de gênero para dar suporte a pesquisa de campo realizada e compor a discussão dos dados obtidos. A pesquisa de campo foi realizada em uma universidade pública federal brasileira. Os resultados identificaram a ocorrência de múltiplas atribuições das mulheres universitárias, que se somam com as atividades acadêmicas: a maternidade, as atividades domésticas e profissionais extra universidade. Espera-se que os achados contribuam para a construção de um ambiente mais inclusivo, que respeite a maternidade e contribua para a formação de uma sociedade mais igualitária.
Big and Learned and Far From Simple: Intellectual Narration in "The Plain People of Ireland" and The Third Policeman
Authors: Glass Maggie
Published: July 2021

Brian Ó Nualláin is a man of many names and many voices. The narrative power he posseses is exemplified when comparing 'The Plain People of Ireland' segments of the Cruiskeen Lawn columns in The Irish Times, penned under the pseudonym Myles na gCopaleen, and the voice of the nameless narrator in Flann O'Brien's The Third Policeman. Within these two works, the position of the intellectual in Irish society is portrayed through quite different lenses: the self-confident, perpetually correct Myles, and the timid, obsessively rational narrator. While both voices are erudite and authoritative, their positioning within the environments they inhabit could not be more different. This article examines the positioning of the 'intellectual narrator' in Ireland, as portrayed by the various voices of Ó Nualláin, focusing specifically on the tone utilised throughout the respective pieces to differentiate the social standing of the narrators from those they encounter. The mastery of language apparent in both 'The Plain People of Ireland' and The Third Policeman subverts the expected portrayal of a public intellectual, destabalising the inherent class politics that imbue both works without dismantling them all together.
Optimization and Kinetic Modelling of Total Phenols and Flavonoids Extraction from Tilia cordata M. Flowers
Authors: Mitic Milan , Jankovic Sonja , Mitic Snezana , Kocic Gordana , Maskovic Pavle , Dukic Dragutin
Published: July 2021

ABSTRACT The main goal was to optimize and establish the kinetics and the thermodynamics of the extraction process. An investigation into the effects of ethanol concentration (0-100 %), liquid to solid ratio (30-60 mL g-1), extraction temperature (25-65 °C), and extraction time (40-200 min) on the extraction of total phenols (TP) and total flavonoids (TF) from linden (Tilia cordata M.) flowers was performed using single-factor experiments. Experimental results showed that extraction conditions had a significant effect on the extraction of phenolic compounds. The optimized conditions were 50 % ethanol, liquid to solid ratio 60 mL g-1 for 120 min at 55 °C, with values of 17.05 mg GAE g-1 dry weight (d.w.) for TP and 13.32 mg CE g-1 d.w. for TF. Extracted phenolic compounds were analyzed by HPLC. The antioxidant activity of the extracts was evaluated by DPPH and ABTS assays. The applicability of different mathematical models (model based for the unsteady diffusion through the plant material, model based on the film theory and model of Ponomaryov) to describe the kinetics of the extraction process of TP and TF from linden flowers was studied as well. The mathematical models applied showed a good agreement with the experimental results, which allows their application in modelling and optimizing the solid/liquid extraction process to extract TP and TF from linden flowers. Keywords: Extraction conditions, phenolic compounds, antioxidant activity, mathematical models.
Tooth loss in relation to serum cotinine levels - A cross-sectional study from the Belville South area in South Africa
Authors: Kimmie-Dhansay Faheema , Pontes Carla C , Chikte Usuf , Erasmus Rajiv T , Kengne Andre P , Matsha Tandi E
Published: July 2021

Tooth loss constitutes a major public health challenge, sharing common risk factors with non-communicable diseases. To report the relationship between tooth loss and serum cotinine levels in a population sample of mixed ethnic heritage from the Belville South area in South Africa. Cross-sectional epidemiological study.Subjects were invited from 2014 to 2016 according to a consecutive sampling technique and all those who met the inclusion criteria were included. In all, 1876 individuals were included, being 1416 females (75.5%), with a combined average age of 49.5 ± 15.3 years. In total 46.7% of the sample was edentulous, with females presenting a higher proportion than males (50.7% vs. 34.1%, p < 0.001). The relative risk (RR) of being edentulous was higher for females (RR=1.8, 95% CI=1.35-2.41, p<0.001) and for participants with cotinine levels 15-299 ng/ml (RR = 1.37, 95% CI=1.02=1.83, p=0.04) and ≥300 ng/ml (RR=1.51, 95% CI=1.09-2.08, p=0.01). Maxillary incisors and mandibular molars were the most prevalent missing teeth. The burden of tooth loss is high in the studied population sample, as well their unmet needs for dental care. Female gender, tobacco exposure, and aging were associated with partial and total edentulism.
What’s new for the clinician? Excerpts from and summaries of recently published papers
Authors: Yengopal Veerasamy
Published: July 2021

Pulpectomy is a conservative treatment approach for preventing the premature loss of primary teeth that can result in loss of arch length, insufficient space for erupting permanent teeth, impaction of premolars, and mesial tipping of molar teeth adjacent to the lost primary molar. Pulpectomy is a procedure which involves removal of the roof of pulp chamber in order to gain access to the root canals which are debrided, shaped, disinfected, and obturated later with a resorbable material. As a result, the tooth can be maintained in the arch without vital pulp tissue, without compromising the function of the tooth. The most common complications associated with pulpectomy, post-operative pain (PP) and/or swelling, commence after treatment. These are always unpleasant experiences for both patients and clinicians. The apical extrusion of infected debris or irrigation solution during the canal preparation or irrigation procedure may worsen the inflammatory response and cause periradicular inflammation and postoperative pain. It is well-documented that the type of irrigation method affects the amount of apically extruded debris (AED) in permanent teeth. No study has evaluated the effect of different needle types on the intensity and duration of PP after pulpectomy in primary molars. Topçuoglu and colleagues reported on a trial that sought to compare the intensity and duration of postoperative pain after pulpectomy using open-ended needles (OEN) versus sidevented needles (SVNs) in primary upper molars.
The business management training needs of South African Biokineticists to ensure business sustainability
Authors: Lumb Michael James , Marais Karel
Published: July 2021

Background: Business management training is essential for success in the modern era. Health and medical professionals are exposed to knowledge that allows them to treat pathologies. However, their training does not prepare them to manage their practices as businesses and in a sustainable, effective, and efficient manner.Objectives: To investigate the business management training needs of registered South African Biokineticists.

Methods: A quantitative and descriptive research design was used. Sixty-nine registered Biokineticists answered the emailed survey. The survey was sent out on two separate days, two weeks apart. Participants could only answer the survey once. The survey was sent out by the Biokinetics Association of South Africa (BASA). The sample in this study consisted of both male and female participants who graduated between the years of 1985-2019. The survey consisted of demographic questions about their study methods. It also included a 5-point Likert Scale where a score of 1 indicated an exceptionally low need and a score of 5 indicated a very high need for corresponding business processes. The business processes included accounting, business sustainability, corporate social responsibility, ethics, financial management, human resource management, leadership and managerial decision-making, marketing, operational management, and strategic management. A final open-ended question on what other business management training the participant needed was asked at the end of the survey.

Results: Combined high to very high needs (X≥4 on the Likert Scale) for the business management processes explored were: accounting: 28%, business sustainability: 33%, corporate social responsibility: 23%, ethics: 55%, financial management: 35%, human resource management: 29%, leadership and managerial decision-making: 43%, marketing: 41%, operational management: 39%, and strategic management: 33%. Seventy-one percent of the participants who took part in the study suggested that they needed other business management training needs, providing suggestions in the final question. Of the 71% of participants who answered this question, the most important requests identified included information technology (17%), tax- related management and knowledge (19%) and medical aid training for ICD-10 coding (13%). The other 51% of the participants that answered the final question provided suggestions that could be categorised into the areas of business already reported on in the Likert Scale. Sixty-nine out of a possible ±1600 registered Biokineticists who were BASA members completed the survey. This represents a response rate of about 4%.

Conclusion: Business management training needs exist for South African Biokineticists. By addressing these needs, it may lead to improvements in overall patient care, practice management and small business growth which in return can lead to the socioeconomic stimulation of the country.
'n Lied vir donker tye (Wer nur den lieben Gott lässt walten - Wie maar op God wil werp sy sorge)
Authors: Kloppers E
Published: July 2021

Die Covid-19-pandemie het groot lyding veroorsaak en die einde is nog nie in sig nie. Wat help mense in swaar tye, tydens die "lockdowns" van die lewe? Wer nur den lieben Gott lässt walten van Georg Neumark (1621-1681) dien as voorbeeld van 'n lied wat mense in die konteks van geleefde geloof kan bemoedig. Die lied het neerslag gevind in baie Duitse gesangboeke en vertalings daarvan is in gesangboeke oor die wéreld opgeneem. In orrel-voorspele, kantates en ander musiekwerke word dit tot klank gebring. Tydens die Eerste Wéreldoorlog het dit mense in Duitsland getroos, maar is ook vir militaristiese en patriotiese doeleindes gebruik. Die lied speel 'n prominente rol in twee films: Babette 's Feast (1987) en Vaya con Dios (2002). In beide films word getoon hoe die lied mense in die uitlewing van hul geloof 'n stem gee en hoe hulle God se stem daarin hoor. In die artikel kry die agtergrond van die lied en die oorspronklike Duitse teks aandag. Daarna word die vertaling in Afrikaans en die wysigings aan die teks krities bespreek. Ses van die sewe strofes van GBA Gerdener se vertaling in Afrikaans (1931) is opgeneem in die Psalm- en Gesangboek (1944). Vir die Psalm-en Gesangboek (1978) is die teks drasties verkort tot drie strofes. Veranderinge in die weergawe vir die Liedboek van die Kerk (2001) het die band met die oorspronklike teks verder verbreek. In samehang met die treffende melodie (en met aspekte van die ouer weergawe wat nog in mense se himniese geheues lewend is), kan die lied mense steeds bemoedig en hulle aan God se teenwoordigheid herinner. Die resepsiegeskiedenis dui op die voortgaande werking van die lied in verskillende kontekste van geleefde religie.
Die Antroposeen en historiese bewussyn
Authors: Tempelhoff J
Published: July 2021

Sedert die vroeë 2000's het die "Antroposeen" 'n gonswoord geword waarvan natuur- en menswetenskaplikes asook die breë samelewing kennis geneem het. 'n Voorgestelde klassifisering van 'n "Antroposeen-epog" in die geologiese stratigrafie van die planeet, beteken dat die huidige geologiese stratigrafiese tydsindeling uitgebrei word. In werklikheid word verklaar dat meer dissiplines selfs buite die natuurwetenskappe, nodig is om kennis te neem van die toenemende mensgedrewe vernietiging van die aardse ondersteuningstelsel wat lewe onderhou. Hulpbronskaarsheid, omgewingsvernietiging en klimaatsverandering is die gevolg van die mensdom se ekologiese voetspoor. Daar word aanvaar dat vooruitgang en ongebreidelde ekonomiese groei nie volhoubaar is nie. Die toenemende uitwissing van endemiese plant- en dierspesies dui regstreeks op die antropogeniese oorbenutting van menslike hulpbronne. Die mensdom word tans selfs as die agent van omvangryke geologiese verandering uitgesonder - vandaar die gebruik van die term "Antroposeen". Geowetenskaplikes het nog nie konsensus oor die Antroposeen bereik nie. Een groep reken klimaatsverandering is bloot 'n natuurlike proses. Heelwat is krities teenoor die potensiële waarde van samewerking met wetenskaplikes in ander vertakkings van die natuur- en menswetenskappe. Hulle is huiwerig om, sonder die nodige bewysgronde, veranderinge van "sogenaamde nuwe insigte" in die breër raamwerk buite hul spesialiteitsterreine te aanvaar. Op hul beurt meen Antroposeen-voorstanders die tyd is ryp vir die aaneenskakeling van geowetenskappe by ander natuur- en menswetenskappe. Ten spyte van omvattende internasionale media-publisiteit en akademiese navorsingswerk, het die Internasionale Kommissie vir Stratigrafie (IKS) in 2018 die voorstel vir 'n nuwe "Antroposeen-epog" deur 'n spesialis Antroposeen Werkgroep (AWG) van die hand gewys. Die werkgroep het juis in opdrag van die kommissie gewerk. Die debat duur egter voort in die Internasionale Unie van Geologiese Wetenskappe (IUGW). Dit mag etlike jare duur voordat die Antroposeen as epog erken word. In Geskiedenis as dissipline, beteken dit dat 'n nuwe historiese bewussyn ontwikkel, waarin vereis word dat die gesprek oor die Antroposeen natuur- en menswetenskappe betrek. Daaruit moet 'n etiese selfbewussyn ontspring om verantwoordelik oor die aarde se verlede, hede en toekoms te besin.
'n Chinese padkaart vir die hervestiging van vrygelate gevangenes: 'n Gevallestudie
Authors: Lötter C
Published: July 2021

Hierdie bydrae is 'n kruis-kulturele oefening, binne 'n filosofiese, interdissiplinêre perspektief, waar gesteun word op die werk van beide Derrida en Lacan oor die verplasing van die betekenaar van sy oorspronklike samehang na 'n vars, vreemde konteks. In die lig van die bewese versuim van hervorming en die onaanvaarbare mislukking van hervestigingspogings in Westerse jurisdiksies (wat Suid-Afrika insluit), word data op uitgesoekte straf- en hervestigingspraktyke in die Volksrepubliek van China ingewin en gekodeer met die oog op die aanbieding van 'n padkaart vir die hervestiging van vrygelate gevangenes op eie bodem. Die uitgesoekte temas wissel van hervestiging tot gevangehouding (in daardie omgekeerde orde). Die data is ingewin by wyse van sekondêre data-analise en gekodeer deur die gebruik van 'n tematiese patroon. Hierdie oefening is geïnspireer deur Braithwaite se belangrike onderskeid tussen hardestigmatiserend-beskamende kulture (Suid-Afrika, die VSA) en integrerend-beskamende kulture (China, Japan). Deur 'n abduktiewe ("abductive") navorsingsbenadering met 'n kultuurvermengingsmetode te verbind, is dit moontlik om data van die Volksrepubliek saam te snoer met waarnemings oor hoe dit bestaande hervestigingstendense in Suid-Afrikaanse pogings tot hervorming van gevangenes kan aanvul. Gegewe die ingewikkelde aard van misdaad, word van 'n interdissiplinêre benadering gebruik gemaak in 'n poging om met behulp van 'n nuwe aanwending van 'n ou teorie en in 'n nuwe konteks 'n beter begrip van misdaad te bekom.
Die eerste 40 jaar van Orania
Authors: Senekal B
Published: July 2021

Orania verteenwoordig 'n unieke verskynsel in Suid-Afrika, en een waaroor daar reeds baie gepubliseer is. Daar is egter nog nie 'n doelgerigte poging aangewend om die geskiedenis van dié dorp op te teken nie. In hierdie artikel word ondersoek ingestel na die dorp se ontstaan en ontwikkeling vanaf die sestigerjare tot op hede. Die studie ondersoek die ontstaan van die idee, sowel as die ontstaan van die dorp tydens die Waterwese-tydperk, en dek ook die pioniersjare (1991-2000). Daar word verder aangetoon hoe hierdie dorp van 'n idee en 'n klein dorp gegroei het tot bykans 2 000 inwoners. Inisiatiewe soos die plaaslike geldeenheid, die Ora, die ontwikkeling van die gemeenskapsbank, die Orania Spaar- en Krediet Koöperatief (OSK), die (her)vestiging van standbeelde en monumente, die oprigting van tersiêre onderrigsentrums, besighede en toerismebedrywighede word bespreek. Uitdagings en suksesse word ook aangeraak, sowel as die volgehoue media-aandag wat dié dorp ontvang.
Onderwyserkennis van assessering - implikasies vir die opleiding van onderwysers
Authors: Du Plessis E , Van Der Westhuizen G
Published: July 2021

Assesseringsgeletterdheid is 'n belangrike komponent van die professionele voorbereiding van onderwysers. Onderwysers moet hierdie kennis toepas, deel maak van hulle pedagogiese inhoudskennis en deur praktykervaring daarop voortbou. Die navorsingsvraag in hierdie studie word gelei deur die vraag: Wat behels onderwysers se ervaring en kennis van assessering nadat hulle 'n program vir die Nagraadse Onderwyssertifikaat (NOS) aan 'n afstandsonderriginstansie voltooi het? 'n Totaal van 20 diensdoende onderwysers is doelgerig gekies en 14 deelnemers het ingestem om aan die studie deel te neem. Die ouderdom van die vyf manlike en nege vroulike deelnemers het tussen 26 en 54 jaar gewissel. Die onderwysers, wat almal minstens vyf jaar se praktykervaring gehad het, moes oop vrae beantwoord oor die doeleindes van assessering, hulle eie sienings rakende goeie assesseringspraktyke, die rol van terugvoer en handelinge in assessering wat daarop gemik is om leer te optimaliseer. Die bevindings van die studie word bespreek aan die hand van Bereiter se raamwerk van kennisbou in die onderwys en die maniere waarop kennisoortuigings in professionele leer tot die uitbouing van pedagogiese inhoudskennis bydra. Die hoofbevindings was dat die onderwysers deeglik oor assesseringsdoeleindes en goeie assesseringspraktyke ingelig is en weet hoe om terugvoer te hanteer en wat om met assesseringsinligting te doen om leer te verbeter. Die onderwysers is ook vol vertroue dat hulle kennis en praktyke voldoende en doelmatig is. Hulle voorkeurpraktyke is daarop gerig om leerderprestasie te verbeter. Die onderwysers het 'n behoefte aan opleiding in die gebruik van taksonomieë en tegnologie, en het 'n verlenging van onderwyspraktykervaring voorgestel. Die implikasies hiervan vir die opleiding van onderwysers en voortgesette professionele leer is ten slotte bespreek.
Native gel electrophoresis and Western Blot transfer of Kai-protein complexes v1
Authors: Köbler Christin , M Schmelling Nicolas , Pawlowski Alice , Spät Philipp , Scheurer Nina , LCB Berwanger Lutz , Macek Boris , Axmann Ilka , Wilde Annegret
Published: July 2021

This protocol could be used to analyze Kai-protein complexes in Clear-native PAGE perform Western Blot transfers of large native protein complexes with a semi dry blotting system perform the immunodetection of his-tagged proteins with a single monoclonal anti-his antibody conjugated to horseradish peroxidase (HRP) that catalyses the chemical reaction of the substrate ECL generating a chemiluminescence signal
Role of Fine Needle Aspiration Cytology in Effective Management of Patients with Granulomatous Inflammation in Neoplastic and Non-Neoplastic Lesions
Authors:   Senior Resident, Department of Pathology, Surat Municipal Instbitute of Medical Education and Research, Surat, Gujrat, India, Patel Dr. Drashti Jay , Shukla Dr. Ashwini Arool ,   Professor (Additional), Department of Pathology, Surat Municipal Institute of Medical Education and Research, Surat, Gujrat, India, Jivani Dr. Toral B ,   Assistant Professor, Department of Pathology, Surat Municipal Institute of Medical Education and Research, Surat, Gujrat, India
Published: July 2021

Background: Granulomatous inflammation is a common diagnosis given in fine-needle aspirationcytology (FNAC) and it is a type of chronic inflammation in which tissue reaction appears followingcell injury. Aims: To assess the usefulness of the cytological study in the diagnosis of granulomatouslesions. Materials and Methods: An observational study is done based on cytomorphologicalevaluation of 156 cases of granulomatous inflammation diagnosed at the Department of Pathology,in Surat Municipal Institute of Medical Education & Research over 18 months from February 2018 toJuly 2019. Results: Out of the total of 156 cases of granulomatous inflammation, tuberculosis wasthe most common finding in 111 cases (71.15%), followed by fungal infection (05 cases). The maleto female ratio was 1.0 to 1.4. The most commonly affected age group was 21 to 30 years.Conclusions: All the cases of granulomatous inflammations are analysed for definitive diagnosis toprovide early and proper treatment of underlying diseases, malignancies or lymphoma.
Word-Formational Formant as a Tool of the Process of Native Speakers’ Ethnocultural Identity (Case Study: Dialect Derivatives with the Formant –уш/а)
Authors: Araeva Liudmila A. , Lushpey Anastasiya A.
Published: July 2021

Modern multicultural space is a result of globalisation processes at all levels of human activity. However, a complex of tendencies towards unification gives rise to academic interest in the study of language in the aspect of its functional characteristics as a way of forming ethnocultural entity of a linguistic community. Dialects are a specific language subsystem, which has its own unique units for the process of nomination of persons, artifacts and natural facts of the surrounding reality. Due to its sphere of functioning, the word-formation formant –уш/а is a linguistic unit that is used by the dialect speakers for an alternative to the literary language way of creating nouns denoting plants, animals, and fish. Derivative words with such a suffix represent the value paradigm, verbalised through the relevant for a person qualities of objects, such as taste, colour, shape, place of growth, and functional properties. The appeal to dialectal derivative vocabulary with the archaic suffix, which is not currently used in the literary Russian language, gives an opportunity to describe the cognitive processes of the linguistic creativity of the Russian-speaking population in terms of its typical and unique features
A Word and Music in the Vocal Cycle of Rodion Shchedrin Based on the Osip Mandelstam’s Poem «My Age, My Beast»
Authors: Sinel’nikova Olga V.
Published: July 2021

The article is devoted to the issue of the synthesis of words and music in the vocal cycle of Rodion Shchedrin «My Age, My Beast» with lyrics by Osip Mandelstam, created by the order of V. Ashkenazi. The author studies the composer’s original approach to combining words and music and concludes that a number of innovations introduced by Shchedrin and transforming the traditional genre of the vocal cycle led to this result. Firstly, the composer uses fragments of Anna Akhmatova’s diaries where she recalls the dramatic moments of O. Mandelstam’s life – his arrest, exile, and death of the poet as the literary basis of the cycle. Fragmentary diary entries by A. Akhmatova in linear and counterpoint combination with the poetic texts by O. Mandelstam give rise to a diversified semantic polyphony of the composition. Secondly, the individual editing principle of R. Shchedrin’s artistic thinking contributes to an increase in the associative perception of O. Mandelstam’s poetry in its synthesis with music. Stages of the drama of R. Shchedrin’s composition, fixing the milestones in life and creative path of the poet are traced in the article. The author of the article analyzes the features of the composer’s musical language, consonant with the complex-associative poetry of O. Mandelstam. The analysis of the vocal cycle of R. Shchedrin became the starting point of the author’s reflections on the tragedy of the greatest poet of the 20th century in the unity of his poems and destiny, on the cruel lessons of Russian history and the victims of the totalitarian system
The Influence of E-service Quality On Marketplace Platform Towards Customer Loyalty
Authors: Mat Daud Nurul Izyan , Aziz Nur Athirah Syazwani , Mohd Fatihah , Sabri Nur Ain Ayunni
Published: July 2021

With the increasing of online marketplaces, online platform must come out with the solutions or ways in order to engage their relationship with customer. Hence, this study aims to examine the roles of e-service quality of online platform in customer loyalty. Convenience sampling technique was used, and data were collected using questionnaires. A sample of 248 respondents among final year students of Universiti Malaysia Kelantan, Pengkalan Chepa were selected. From the obtained results, study showed that there is a significant relationship between independent variables; reliability and security in Shopee platform towards the customer loyalty, respectively. With this finding, it can help and provide the marketers in terms of e-service quality to develop the customer engagement for the sake of customer loyalty. Therefore, the sustainability of the business can be maintained
The Effect of Microfinance Bank Services on Women Empowerment: The case for Women Entrepreneurs in Irbid, Jordan (SMEs)
Authors: Abdallah Alshammari Ahmed Mahmoud , Wan Daud Wan Mohd Nazri
Published: July 2021

Generally, women, entrepreneurs face problems in accessing funding due to factors that stem from cultural values, ??societal needs, family ties, illiteracy, gender discrimination, strict government policies, economic crisis, and the lack of training in entrepreneurship and skills acquisition that hinders entrepreneurial activities. This study was conducted to examine the impact of microfinance bank services in empowering female entrepreneurship in Irbid Governorate. The study used a cross-sectional survey research design consisting of 20,000 registered businesswomen. A total of 392 working women were selected using stratified sampling technique and the data was analysed using Least Square Structural Equation Modelling (PLS-SEM) with the help of SmartPLS3 software. The results showed that microfinance loans, microfinance savings, and financial interventions or donations had a significant, positive impact on empowering women's businesses in Irbid, Jordan. The study concluded that microfinance deposits could elevate women’s income and act as a guarantee to obtain loans and other microfinance services. Consequently, microfinance institutions (MFIs) should empower more women-owned businesses. In addition, the government through the Central Bank of Jordan should reduce the interest rate of microfinance banks to attract more female entrepreneurs and create more microfinance bank plans and financial intervention packages to enhance financial services to ensure donations and funds reach women entrepreneurs.
Digital Advertising Features on Customer Purchase Intention
Authors: Yin Yin Julia Tan , Feng Yan Li
Published: July 2021

Advertisement denotes a standard strategy of attracting public interest and facilitating purchase decisions. This research aims to determine the digital advertisement feature effects on consumer purchase intent in Malaysia. A cross-sectional design was employed to gather quantitative data from 361 Malaysian respondents with a digital survey. Additionally, SPSS was utilised to assess the digital advertising-purchase intention relationship. Resultantly, pictorial cues, repetition, and sensory stores significantly influenced Malaysian consumers’ purchase intention. Following the motivation theory, this research identified a relationship between digital advertising feature effects and purchase intention power that proved inadequate in past studies. The study outcome proved vital in rearranging advertising methods to be more appealing and informative for customers to receive clear and precise knowledge.
Simulation of a strictly φ-sub-Gaussian generalized fractional Brownian motion
Authors: Vasylyk O. I. , Lovytska I. I.
Published: July 2021

In the paper, we consider the problem of simulation of a strictly φ-sub-Gaussian generalized fractional Brownian motion. Simulation of random processes and fields is used in many areas of natural and social sciences. A special place is occupied by methods of simulation of the Wiener process and fractional Brownian motion, as these processes are widely used in financial and actuarial mathematics, queueing theory etc. We study some specific class of processes of generalized fractional Brownian motion and derive conditions, under which the model based on a series representation approximates a strictly φ-sub-Gaussian generalized fractional Brownian motion with given reliability and accuracy in the space C([0; 1]) in the case, when φ(x) = (|x|^p)/p, |x| ≥ 1, p > 1. In order to obtain these results, we use some results from the theory of φ-sub-Gaussian random processes. Necessary simulation parameters are calculated and models of sample pathes of corresponding processes are constructed for various values of the Hurst parameter H and for given reliability and accuracy using the R programming environment.
"Close Connection" Category in International Civil Procedure and in Conflict of Laws
Authors: Terentyeva L. V.
Published: July 2021

The use of "close connection" in conflict of laws area and in international civil procedure preconditions the question whether it is possible to interpret it uniformly both as a basis for establishing the jurisdiction to resolve cross-border private law dispute, and as a basis for choosing the applicable law.

When studying close connection within the framework of conflict-of-laws regulation, the author of the paper, along with the concept of "close connection" examines the concepts of "connection with only one country" and "the closest connection". The paper also discusses the concept of Proper law which, as a rule, in the Russian doctrine is identified with the category of close connection.

Analysis of the close connection as the basis for establishing jurisdiction has led to the conclusion that it is necessary to apply a differentiated approach to determining the content of close connection within the framework of Conflict of Laws and international civil procedure. This assumption is based on the fact that when establishing jurisdiction to consider cross-border private law disputes on the ground of a close connection, a special task is solved to overcome the conflict of jurisdiction while observing the principle of equality between judicial procedures of different states, as well as the principle of international judicial cooperation. In addition, within the framework of the international civil procedure, the concept of “foreign element” preconditioning the manifestation of a close connection of the disputed legal relationship with the court of the state, can be endowed with additional content except the content attached to the foreign element within the framework of the conflict of laws, namely: obtaining evidence abroad; enforcement of a court order abroad, etc.
The Doctrine and Legal Positions Developed by the Courts in Theft of Someone’s Property Cases
Authors: Kochoi S. M.
Published: July 2021

The paper considers the legal positions developed by the courts in cases of theft of someone’s property. The author is critical of the concept of "judicial doctrine", believing that the courts in essence cannot create a doctrine (theory, science), but notes the significant role of the legal positions of the courts in the formation and development of the doctrine (theory) of theft. The purpose of the work is to find an answer to the question of whether the legal positions of the courts on the application of the legal definition of theft in practice remain relevant (note 1 to Article 158 of the Criminal Code of the Russian Federation), as well as the doctrine about this crime and its elements. Having studied various points of view contained in the scientific literature, as well as the positions of the courts, including those expressed in individual decisions of the highest judicial instance of the country, the author concludes that neither the legal definition of theft nor the doctrine of it has lost its relevance. We should not be talking about the "revision" of legal and scientific structures or the "collapse of the system", but about the crisis of practice and doctrine due to the uncertainty associated with the emergence of new property goods and objects (virtual assets, digital rights, etc.) and forms of encroachment on property that are not covered by any of the features of theft. For this reason, in the absence of answers to the challenges that have arisen, controversial decisions are made in judicial and investigative practice, and contradictory recommendations are proposed in the scientific literature. According to the author, the crisis that has arisen can be solved by introducing legislative amendments to Chapter 21 of the Criminal Code of the Russian Federation aimed at forming norms on new property crimes against property that do not contain elements of theft of someone’s property.