bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Analysis of Asian Carps Parvalbumin Reveals the Evolutionary Divergence Pattern of a Major Fish Allergen
Authors: NG Judy Kin Wing , Xiong Qing , SHI Ling , Wai Christine Yee Yan , Shin Soo-Kyung , AO Fu Kiu , Leung Agnes Sze Yin , Leung Nicki , Leung Ting Fan , Tsui Stephen Kwok-wing
Published: December 2022

Background Asian carps are popular freshwater fish species in Hong Kong
and served as an important protein source for infants. Grass carp
parvalbumin was reported to have higher allergenicity than other
commercially important fishes (salmon and cod) in terms of IgE
reactivity. Objective To identify allergens in Asian carps and study the
divergence pattern of allergens. Method Three complete Asian carps’
genomes were constructed by hybrid assembly approach. All the homologs
of known and putative allergens were identified based on sequence
homology at the genomic level. The gene structures, expression level and
protein conformations of parvalbumin were revealed using bioinformatics
tools. Results Parvalbumin is the major allergen in grass carp tested by
indirect ELISA. Nine homologs of parvalbumin were identified in the
genome of grass carp, in which Cid_PV2 exhibited highest sequence
similarity to the reported group 1 allergen of grass carp, Cten i 1.
Similarly, ten parvalbumin homologs were identified in the genome of
bighead and black carp respectively, in which Mpi_PV7 and Hno_PV7 were
identified as the putative allergenic homologs. The expression profile
of parvalbumin revealed alternative usage of homologs in different
tissues of Asian carps. Moreover, gene copy numbers of parvalbumin
gradually expanded in bony fish and two gene clusters of parvalbumin
were identified inside the genomes of Asian carps. Conclusion All the
homologs of Asian carps’ parvalbumin were accurately identified and gene
divergence contributed to the formation of allergenic homologs. Together
with a comprehensive gene sequence profile of carps’ parvalbumin, those
could be applied to achieve a more precise clinical diagnostic test and
would ultimately assist the design of preventive treatment by
immunotherapy of fish allergy.
Plastid Genome Assembly Using Long-read data (ptGAUL)
Authors: Zhou Wenbin , Armijos Carolina , Lee Chaehee , Lu Ruisen , Wang Jeremy , Ruhlman Tracey , Jansen Robert , Jones Alan , Jones Corbin
Published: December 2022

Although plastid genome (plastome) structure is highly conserved across
most seed plants, investigations during the past two decades have
revealed several disparately related lineages that have experienced
substantial rearrangements. Most plastomes have two inverted repeat
regions and two single-copy regions with few dispersed repeats. However,
the plastomes of some taxa do harbor long repeat sequences
(>300 bp). These long repeats make it difficult to assemble
complete plastomes using short read data, leading to misassemblies and
consensus sequences that have spurious rearrangements. Long read
sequencing can potentially overcome these challenges. However, there is
no consensus as to the most effective method for accurately assembling
plastomes using long read data. Here, we generated a pipeline, plastid
Genome Assembly Using Long-read data (ptGAUL) to address the problem of
assembling of plastomes using long read data from Oxford Nanopore
Technologies (ONT) or Pacific Biosciences (Pacbio) platforms. We
demonstrated the efficacy of the ptGAUL pipeline using 16 published long
read datasets. We showed that ptGAUL produces accurate and unbiased
assemblies. Additionally, we applied ptGAUL to assemble four Juncus
(Juncaceae) plastomes using ONT long reads. Our results revealed many
long repeats and rearrangements in Juncus plastomes compared with basal
lineages of Poales.
Impedance Differential Protection for Double Circuit transmission Lines Based on Distributed Parameters
Authors: challab talib , Seyedi Heresh , Rostami Naghi
Published: December 2022

This paper presents an impedance differential protection scheme for a
double-circuit transmission line. Current and voltage measurements at
both line ends enable the formulation of a differential impedance that
serves as an effective protection standard for transmission lines. The
proposed method takes into consideration the effects of the line’s shunt
capacitance since it is based on the distributed parameter line model.
The proposed protection system is able to detect the faults and also has
the ability to determine the fault location. In addition, the relay
offers dependability, and selectivity for differentiating between
internal and external faults, thereby stays steady against external
faults. The proposed method has been tested with varying fault
resistances and under various fault conditions. The effectiveness,
security, and dependability of the method are verified by the simulation
results.
Pilot study rectifies real-world study design to support regulatory decision making
Authors: Major-Pedersen Atheline , Aberle Jens , Sbraccia Paolo , Rathor Naveen , Olsen Anne Helene
Published: December 2022

Purpose: To evaluate the feasibility of a drug utilization
study (DUS) investigating real-world use of Saxenda
and Victoza in Europe. Economic and time constraints
may incite researchers to avoid formalized pilot studies. Here, we
report results of a pilot study which rectified the ensuing DUS
protocol, thus ascertaining fit-for-purpose data availability and
quality, and supporting regulatory decision making. Methods: A
retrospective multicenter medical chart review in Germany and Italy, 6
months after Saxenda (liraglutide 3.0 mg, a
once-daily human glucagon-like peptide-1 analog for weight management)
launch, ahead of a full DUS. Collected data included: site
characteristics, patient demographics, medical history, drug utilization
(e.g., brand, dose, indication, weight-related comorbidities). Target
study population: 100 initiators (25 Saxenda and 25
Victoza initiators in both Germany and Italy).
Informed consent was obtained before medical-chart data extraction.
Results: Overall, 218 sites were contacted. Fifteen sites (nine
in Italy; six in Germany) enrolled initiators. There were 39 Saxenda
initiators (33 in Italy; six in Germany) and 52
Victoza initiators (31 in Italy; 21 in Germany).
Data were available for all Saxenda initiators and
all Victoza initiators in Italy, and for 12 of 21
Victoza initiators in Germany. In nine of the 12
initiators, only target dose was recorded, with no current dose
provided. Conclusions: The pilot study indicated a poor
enrollment feasibility of Saxenda initiators in
Germany and an unfit-for-purpose dose-related data quality. Based on
these findings, refinements were implemented to the ensuing DUS
protocol, thus ensuring robust real-world data to support regulatory
decision making.
Power Distribution Control and Performance Assessment of a Wind Energy fed Microgrid Integrated with Hybrid Energy Storage System
Authors: Behera Pradyumna Kumar , Pattnaik Monalisa
Published: December 2022

The present work proposes a coordinated power distribution control of
wind-energy fed self-excited induction generator (SEIG) based
low-voltage direct current (LVDC) autonomous microgrid. The battery and
supercapacitor (SC) hybrid energy storage system (HESS) is interfaced
with the common 48 V LVDC bus using a parallel-active configuration
through two bidirectional converters. The prime idea of hybridization is
to limit the instantaneous peak current demand and also to alleviate the
charge/discharge stress during transients, thus reducing the size of the
battery. The developed autonomous LVDC system with the supervisory power
distribution control scheme (PDCS) is experimentally validated for
different operating modes. The comparative experimental result analysis
substantiates the efficacy of the proposed PDCS along with seamless
transition between various modes.
A platinaalapú kemoterápia szerepe a húgyhólyagrák kezelésében - az elmúlt 10 év klinikai tapasztalatainak feldolgozása
Authors: Módos Orsolya , Bozsaki Ákos , Nagy Cintia , Nagy Nikolett , Csizmarik Anita , Keresztes Dávid , Oláh Csilla , Váradi Melinda , Horváth András , Szendrői Attila , Szűcs Miklós , Keszthelyi Attila , Nyirády Péter , Szarvas Tibor
Published: December 2022

Bevezetés: Az invazív húgyhólyagdaganat disszeminációjának megállítására első vonalban a platinaalapú kemoterápia áll rendelkezésünkre. Ez a kezelés azonban csupán a betegek körülbelül felében bizonyul hatékonynak. Jelen vizsgálataink célja az volt, hogy Intézetünkben a kemoterápiával kezelt hólyagrákos betegek klinikopatológiai adatait feltérképezve információt nyerjünk arról, hogy azok hatással vannak-e a platinaalapú kezelés hatékonyságára, illetve a betegség kimenetelére. Betegek és módszerek: A Semmelweis Egyetem Urológiai Klinikáján 2007 és 2017 között platinaalapú kemoterápiával kezelt hólyagrákos betegek adatait gyűjtöttük össze. Öszszefüggéseket kerestünk a klinikai paraméterek és a betegek progressziómentes és teljes túlélése között. Eredmények: Összesen 135 beteg adatait dolgoztuk fel, akik között 97 férfi (72%) és 38 nő (28%) szerepelt. A medián életkor a kezelés megkezdésekor 63 év volt (40–82). A kemoterápia indikációja szerint három csoportot különböztettünk meg: 1) Adjuváns kezelésben részesültek azok a betegek, akik a cystectomia szövettani eredménye szerint lokálisan előrehaladott lelettel (n=42/135; 31,1%) és/vagy nyirokcsomó-áttéttel (n=19/135; 14,1%) vagy mindkettővel (n=28/135; 20,7%) rendelkeztek. 2) Induktív kezelésben részesültek, akiknek a tumora a cystectomia után progrediált (lokális recidíva n=5/135; 3,7%, távoli szervi metasztázis n=7/135; 5,2%, és nyirokcsomóáttét n=1/135; 0,8%). 3) Palliatív kezelésben részesültek azok a betegek, akiknél radikális sebészi kezelésre nem volt lehetőség (n=33/135; 24,4%). Az induktív kezelésben részesülők tumora a cystectomia után progrediált (lokális recidíva n=5/135; 3,7%, távoli szervi metasztázis n=7/135; 5,2%, és nyirokcsomóáttét n=1/135; 0,8%). Palliatív kezelés esetén radikális sebészi kezelésre nem volt lehetőség (n=33/135; 24,4%). Eredményeink alapján az induktív terápiában részesülők túlélése volt a legkedvezőtlenebb (p<0,001). A nyirokcsomóáttét megléte szignifikánsan jobb prognózissal járt együtt (p=0,036). A cukorbetegség szignifikáns rizikófaktornak bizonyult a túlélés tekintetében (p=0,027). A kezelés alatt radiológiai progressziót nem mutató páciensek szignifikánsan tovább éltek (p=0,047). Következtetések: Eredményeink alapján a kemoterápia indikációja, a progresszió típusa, valamint a cukorbetegség lényegesen befolyásolhatja a platinaalapú kezelésnek alávetett betegek túlélését. E klinikai paraméterek mellett a tumorok molekuláris sajátságait is figyelembe vevő predikciós módszerekre lenne szükség a terápiás döntések hatékonyságának javítása érdekében.
The co-dynamics of malaria and tuberculosis with optimal control strategies
Authors: Alzahrani A.K. , Khan Muhammad
Published: December 2022

Malaria and Tuberculosis are both the severe and causing death diseases in
the world. The occurrence of TB and malaria as a coinfection is also an
alarming threat to the human. Therefore, we consider a mathematical model of
the dynamics of malaria and tuberculosis coinfection and explore its
theoretical results. We formulate the model and obtain their basic
properties. We show that at the disease free case each model is locally
asymptotically stable, when the basic reproduction number less than unity.
Further, we analyze the phenomenon of backward bifurcation for coinfection
model. For the sub models, we present the local stability for the disease
free case whenever the basic reproduction number less than 1. Further, an
optimal control problem is presented to investigate the dynamics of malaria
and tuberculosis coinfection. The numerical results with different scenarios
are presented. The mathematical model with and without control problemare
solved numerically using the Runge-Kutta backward and forward scheme of
order four.
"Inspiring" but Not True: An Added Glimpse of the RLDS Stance on the Book of Mormon
Authors: Midgley Louis
Published: December 2022

Since the late 1960s RLDS "liberals" have argued that the Book of Mormon should not be read as an authentic ancient history. This novel reading of the Book of Mormon has been part of a sustained effort by the RLDS hierarchy to make the Reorganization conform more closely with Protestant liberal approaches to the Bible. I demonstrate that the RLDS hierarchy has encouraged changes in the way the Book of Mormon is read by RLDS intellectuals. I then examine the arguments of Roger Launius, currently the foremost RLDS historian, who has recently insisted that the Book of Mormon ought to be read as "inspiring" frontier fiction. I also describe and criticize his claim that any concern with the historical authenticity of the Book of Mormon is not serious historical scholarship, which he wants focused on issues currently fashionable among secularized historians.
The Type at the Border: An Inquiry into Book of Mormon Typology
Authors: Clark Robert E.
Published: December 2022

A certain combination of temperament and upbringing can lead to a sense of alienation from the scriptures’ meaning. This paper considers the role that types might play in overcoming that alienation as they mediate between scriptural understanding and human experience, permitting deeper insight into both. The difficulties and possibilities inherent in such an approach are considered by way of typological analysis of the figures of Abinadi and the brother of Jared.
Comments on the Book of Mormon Witnesses: A Response to Jerald and Sandra Tanner
Authors: Roper Matthew
Published: December 2022

Critics of the Book of Mormon frequently claim that some of the Book of Mormon witnesses later doubted or denied their testimony of the Book of Mormon. They also claim that the activities of the Three Witnesses while out of the Church cast doubt upon the reliability of their earlier written testimony. I review evidence for these claims and also discuss the issue of what may constitute a witness of the Book of Mormon and whether the witnesses ever doubted or denied their testimony of the Book of Mormon. Evidence for later disbelief in the Book of Mormon is examined and found to be unpersuasive. Several miscellaneous issues relating to Jerald and Sandra Tanner’s criticisms of the Book of Mormon are also detailed.
Stories of students with autism, their lived experiences and journey throughout education: A narrative analysis
Authors:   , Pickard-Hengstenberg Heather
Published: December 2022

Students with autism face a multitudinous array of day-to-day internal horizontal transitions, and school-to-school external vertical transitions, during their educational journey. This research explores the educational and lived experiences of five students with autism. Its intentional aim is to promote greater understanding about their unique needs, to positively inform, influence, policy, and practice. To contribute towards the reduction of autistic disabling educational barriers, in turn enabling students to reach their full potential. Narrative analysis methods were used to explore participants unique first-person experiences, to interpret and analyse their fabula, transcribed spoken words, and sjuzet, non-verbal cues, as a means to represent their true reality. Transition and change theory models were adapted as a tool to represent these findings. Case comparisons were made to identify common themes, which were then compared with general and reviewed literature, to gain a comprehensive understanding about the educational experiences of the wider autistic population. Findings indicated that all participants faced a wide range of academic and emotional-social difficulties, termed concurrent stressors. It was evident that a diagnosis and autism specific support did not guarantee a reduction in stressors and improvement in state of health, due to core autistic features such as co-occurring depression, obsessive phobias, and inescapable social difficulties. All participants experienced the greatest number of stressors and a major deterioration in health, during the secondary phase. All participants experienced a reduction in stressors and improvement in health, during the sixth form phase. The university phase had mixed results with the minority of participants’ health deteriorating, or remaining stable, and the majority of participants showing an improvement overall. This research concludes, autism is a lifelong disabling condition, requiring early diagnosis, to ensure that stressors are understood, supported through autism specific support, to minimise deterioration in state of health, and to improve educational, academic, emotional-social, experiences.
Studying molecule-surface interactions using magnetically manipulated molecular beams
Authors:   , Alkoby Yosef
Published: December 2022

Molecular beam techniques contribute crucial knowledge for a wide range of research fields and applications[1, 2]. The goal of this PhD thesis is to contribute to the development of the new magnetic molec-ular interferometry technique and use it to study fundamentally im-portant molecule-surface systems in their ground state. The thesis describes both surface scattering experiments and the development of new instrumentation and experimental methods which make this technique more powerful and insightful. The development, character-isation and testing of a new direct beam line, capable of magnetically analysing the molecular beam without scattering from a surface, is presented. This new addition to the instrument enables gathering important information about the composition and properties of the molecular beam and its response to magnetic fields. This type of infor-mation will be particularly crucial when extending the interferometry technique to molecules where the magnetic Hamiltonian is not well known. Scattering experiments of hydrogen beams from graphene, copper and salt surfaces were performed, gaining unique quantum in-formation about the scattering process. Using magnetic manipulation, we can characterise the different quantum rotational projection states of the molecules before and after scattering from a surface and detect subtle changes in the quantum state during the scattering event.Both the scattering and the direct beam experiments presented in the thesis, were analysed by solving the magnetic evolution quantum mechanically. The results show that the scattering of hydrogen from a lithium-fluoride (001) surface into different diffraction channels, is highly dependent on the rotational projection states, i.e. the orien-tation of the molecular rotation of the incident molecules. In con-trast, the specular scattering of flat copper, Cu(111), and graphene surfaces shows no obvious change in the rotational state populations upon scattering. Further helium and deuterium beams experiments are presented, enhancing our understanding of the molecular magnetic interferometer and validating our analysis methods.
Uma pista para a gênese das ciências normativas
Authors: Topa Alessandro
Published: December 2022

Quais considerações levaram Peirce a introduzir as ciências normativas de Ética e Estética para a arquitetônica de inquéritos filosóficos que ele delineou primeiramente, e realizou parcialmente em Minute Logic [Lógica Meticulosa] de 1902? No artigo em mão, nós endereçamos a primeira questão focando nas taxonomias dos fins últimos da ação produzidos por Peirce em 1900 e 1901. Enquanto em 1898 Peirce tinha excluído Ética do domínio de inquéritos filosóficos, Minute Logic refleti sobre uma revisão completa do conceito de Ética, que diz que há três níveis de inquéritos éticos. O nível mais fundamental dos três é o anteriormente excluído “terceiro ramo [da filosofia], relativo aos fins” (R 435:10, 1898). Como Peirce repetidamente referenciou sua classificação dos fins últimos da ação apresentado na sua crítica de Grammar of Science [A gramática da Ciência], do Karl Pearson, em dezembro de 1900, essas taxonomias não são meras progenitoras da “ética pura”, mas sim representadoras da sua primeira conquista fundamental no domínio da ciência normativa pré-lógica.
ACTA AMBIENTAL CATARINENSE: 20 ANOS DIVULGANDO CONHECIMENTOS
Authors: Lutinski Junir Antônio , Mello Garcia Flávio Roberto , Müller Eliara Solange
Published: December 2022

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Analisis Korelasi antara Pengangguran, Kemiskinan, dan Ketimpangan Pendapatan di Provinsi Sumatera Barat
Authors: Sari Widia May Wulan , Putri Dewi Zaini
Published: December 2022

The purpose of this study is to explore the correlation between unemployment,poverty, and income inequality in West Sumatra. We use secondary data whichis in the form of time series with a period of 2000 to 2020, where in collectingdata, documentation techniques and literature studies are applied which areobtained from related institutions. The variables of this study include:unemployment, poverty and income inequality. The research method used isPearson Product Moment correlation, using normality test, correlation test andt test. The results show that: (1) unemployment has a positive and significantcorrelation with poverty in West Sumatra. (2) income inequality is negativelyand significantly correlated with poverty in West Sumatra. (3) unemployment isnegatively and significantly correlated with income inequality in West Sumatra.Structural Equation Modeling (SEM).
Analisis Kausalitas Indeks Pembangunan Manusia Pengangguran Pertumbuhan Ekonomi dan Ketimpangan Pendapatan di Indonesia
Authors: Putra Panca Gunawan , Anis Ali
Published: December 2022

This study aims to analyze: (1) The causality relationship between unemployment and the human development index, (2) The causal relationship between economic growth and the human development index, (3) The causal relationship between income inequality and the human development index, (4) The causal relationship between economic growth and unemployment, (5) Causality relationship between income inequality and unemployment, (6) Causality relationship between income inequality and economic growth, (7) Long-term and short-term relationship between human development index, unemployment, economic growth and income inequality in Indonesia. The data used is panel data from 34 provinces in Indonesia during the 2011-2020 period. The analytical method used is Panel Vector Error Correction Model (PVECM) and Panel Granger Causality Test. The results of this study indicate that there is a relationship: (1) Two-way causality between unemployment and the human development index, (2) Economic growth to the human development index, (3) Income inequality to the human development index, (4) Economic growth to unemployment, ( 5) Income inequality to unemployment, (6) Income inequality to economic growth, (7) There is a long-term relationship between unemployment and the human development index which has a positive effect, economic growth has a negative effect on the human development index and income inequality on the human development index has a positive effect negative.
Pengembangan Aplikasi Modul Elektronik (E-Modul) Pada Mata Pelajaran Administrasi Sistem Jaringan
Authors: Dion Dion , Saputra Hadi Kurnia
Published: December 2022

Keberhasilan suatu proses pembelajaran untuk mencapai tujuan pembelajaran tidak terlepas dari media dan bahan ajar yang digunakan. Mengingat waktu pembelajaran tatap muka yang terbatas dengan volume materi pembelajaran yang harus disampaikan, dibutuhkan media dan bahan ajar yang tepat agar siswa tetap dapat melakukan pembelajaran diluar pertemuan tatap muka. Pengembangan Modul Elektronik (E-Modul) bertujuan agar siswa tetap dapat mempelajari materi mata pelajaran administrasi sistem jaringan secara mandiri tanpa harus melakukan pembelajaran tatap muka. Dalam pengembangannya, model pengembangan yang digunakan adalah model 4D, sedangkan dalam pembuatan aplikasinya menggunakan visual app builder FlutterFlow. Pengembangan ini menghasilkan sebuah aplikasi android E-Modul pada mata pelajaran administrasi sistem jaringan  yang sudah mengintegrasikan silabus, materi, jobsheet, video tutorial, dan evaluasi dalam satu aplikasi yang dapat digunakan oleh siswa untuk mempelajari materi pembelajaran diluar pembelajaran tatap muka. Aplikasi E-Modul yang dikembangkan telah melalui uji validitas dan praktikalitas. Hasil uji validitas menunjukkan nilai sebesar 89,75% sedangkan hasil uji praktikalitas menunjukkan nilai 94% oleh guru dan 81.4% oleh siswa.Kata kunci : E-Modul, Administrasi Sistem Jaringan, 4D, Android The success of a learning process to achieve learning objectives is inseparable from the media and teaching materials used. Given the limited face-to-face learning time with the volume of learning material that must be delivered, appropriate media and teaching materials are needed so that students can still carry out learning outside of face-to-face meetings. The development of the Electronic Module (E-Module) aims to enable students to learn network system administration subject matter independently without having to do face-to-face learning. In its development, the development model used is the 4D model, while in making the application it uses the FlutterFlow visual app builder. This development produces an Android E-Module application in the subject of network system administration which has integrated syllabus, materials, jobsheets, video tutorials, and evaluations in one application that can be used by students to study learning material outside of face-to-face learning. The developed E-Module application has gone through validity and practicality tests. The results of the validity test showed a value of 89.75% while the results of the practicality test showed a value of 94% by teachers and 81.4% by students.Keywords: E-Modul, Network System Administration, 4D, Android
Analyse de L’euphémisme Trouvé Dans Le Journal de « BBC News Afrique »
Authors: Plorensa Br Tarigan Maike Airin , Pramuniati Isda
Published: December 2022

La recherche a pour but d’analyser l’euphemisme trouvée dans les phrases des journaux numérique français. En outre, cette recherche vise également à décrire les différents classifications d’euphémisme et à identifier les raisons de l’euphemisme trouvée dans les phrases des journaux numérique français. La méthode de cette recherche est descriptive qualitative et le sujets de recherche est le journal numérique français de «BBC News Afrique» sur du thématique «Monde» à partir de l’édition 2018 jusqu’à 2021. La recherche utilisé la théorie de Samoskaïte (2011:13). Ensuite, les resultants montre qu’il y a 62 données trouvées. Après que les données ont été analysées et classées selon leur classification, la fréquence pour chaque classification est comme suit; la fréquence l’euphémisme du Professionnel apparaît 9 données, la fréquence de l’euphémisme de la maladie apparaît 7 données, la fréquence de l’euphémisme de la mort apparaît 16 données, la fréquence de l’euphémisme de la Sexualité apparaît 4 données, la fréquence de l’euphémisme du Criminel apparaît 11 données, et la fréquence de l’euphémisme de la Politique apparaît 15 données. De plus, on peut donc conclure qu'il existe classification que plus dominante trouvée dans cette recherche est la mort. Il y a 8 raisons d'euphémisme dans cette recherche, à savoir ; comme un langage lubrifiant pour éviter les situations offensants et durs, comme moyen de communiquer avec des mots simples, pour éviter certaines tabous, comme un moyen important de coordonner les relations interpersonnelles entre les personnes, pour sauver le visage d’un orateur et auditeur une conversation, pour faire des références polies à des handicaps physiques ou psychologiques, pour respecter les autres, et pour réduire la perception publique de certaines conditions. Alors, on peut donc conclure dans une raison qu'il existe 1 à 3 les classifications d’euphémisme.Mot clès: Figure de Style de l’Euphémisme, Journal Numérique Français de BBC News Afrique
On Biological Function
Authors: Chen Bohang
Published: December 2022

Eliminativism is a peripheral (if not dead) position in the current biological function debate, and it is roughly presented as the thesis that function terms are eliminable in biological discourse. While eliminativism is often assumed inadequate, a detailed examination of eliminativism is lacking in current literature. Accordingly, this article provides a critical examination of eliminativism. This examination consists of three parts: a clarification of three supporting arguments for eliminativism (based on historical literature), a unified account of eliminativism (inspired in particular by Larry Wright 1976), and a discussion of its validity and some of its implications. This article concludes by briefly addressing the persistent presence of function terms in biological discourse.
Materials and their Biographies
Authors: Mocellin Ronei Clécio , Zaterka Luciana
Published: December 2022

In this article, we are interested in analyzing the biography of metallic titanium (Ti) and its dioxide (TiO2) from a historical, philosophical, and sociological point of view of some of its modes of existence. This biography does not suggest any anthropomorphization of material objects, rather, it is about an attempt to reconcile the reality of science in the present with its history to understand the particularities of materials in contemporary societies. We intend to investigate some properties and characteristics of the “natural” modes of existence and the new properties and implications when these materials gain a new mode of existence, the nanostructured one. This mode of existence refers to a new way of organizing scientific knowledge, an inflection which has been called technoscience, more concerned with what an object will become in the future, then with what it essentially is. In this sense, the proper chemical identity of these substances is one among other modes of existence, into this mode of existence, one must add others which can approach its biological, geological, cultural, technological, economic or geopolitical behavior.
Coping Stress pada Ibu dengan Anak Berkebutuhan Khusus
Authors: Kawuryan Fajar
Published: December 2022

Several studies that have been conducted previously on parents of children with special needs indicate primary caregivers; usually mothers, are at risk for mental health problems.This study aims to determine stress coping in mother with special needs children. This study uses a qualitative phenomenological method using data collection techniques through observation and interview. There are three informants in this study whose are mother of children with special needs. The results showed that among the three informants had different coping stress. The coping stress that was owned by informant I was more oriented to problem focus coping. Informants try to provide the best for their children and provide concrete solutions. The second informant has stress coping which is oriented more to the problem focus coping. This informants can reach this stage even though informants sometimes still appear emotionally angry and pinch when her child is tantrums. Meanwhile, informant III has stress coping which is more oriented to emotional focus coping because the informant does not want to be bothered with the condition of her child so that all the wishes of her child is always fulfilled. It seems as if the informants did not take any action to deal with the existing problems and resigned to the situation and condition of her special neeed child.
Nilai Toleransi Pada Film Semesta Karya Chairun Nissa
Authors: Sa'diyah Kamilatus , Khamdun Khamdun , Fardani Much Arsyad
Published: December 2022

The purpose of this study is to describe the analysis of the value of tolerance in the film Semesta by Chairun Nissa.The research method used is qualitative by using discourse analysis methods. The object of research is the values of tolerance in the Semesta  film in thematic learning in elementary schools, where the fifth grade teacher is the facilitator and the informant is the fifth grade students consisting of 6 students, 3 boys and 3 girls. Data analysis uses discourse analysis techniques that focus on two elements, namely first at the word level and secondly how the events and actors involved in an event are about to be discussed.The results of the study show that there are forms of tolerance in Chairun Nissa's universal film, namely respect for Hindus who practice Nyepi, respect for the cultural heritage of gadget rituals, and respect and love for living beings. The value of tolerance in Film Semesta has been implemented and has been implemented, namely introducing the diversity of Indonesia, praying before and after lessons according to their respective beliefs, doing picket together in turns, listening to others when talking without interrupting the conversation, and respecting the personal rights of others.
VALIDITAS POP UP CRAFT BERBASIS KEARIFAN LOKAL UNTUK MENGENALKAN HURUF ANGKA SISWA TUNAGRAHITA
Authors: Silvia Icha , Aini Alfina Noor , Rosyada Alia Amrina , Samodra Teguh , Masfuah Siti
Published: December 2022

Valid learning media is needed for mentally retarded students so that student learning outcomes increase. This research is a validation stage which is part of research and development. This study aims to examine the validity of the Pop Up Craft at SLB Cendono Kudus based on local wisdom for mentally retarded children. This product consists of Pop Up Craft combined with audio visual media. This media validator consists of media experts and material experts. Based on data analysis, the results obtained were that the media aspect received a score of 3.78 or was in the valid category, the media display aspect received a score of 4.10 or was in the valid category and the program quality aspect received a score of 3.38 or was in the valid category. These results concluded that Pop Up Craft media at SLB Cendono Kudus based on local wisdom is valid for improving learning outcomes for mentally retarded children
La ciudad tridimensional: Tres libros, una avenida, dos edificios (posmodernos) y unas escaleras mecánicas en Santiago de Chile
Authors: Pinchart Saavedra María Pilar
Published: December 2022

Los Edificios Centro Nuevo y Plaza Lyon se terminan con cinco años de diferencia y sintetizan en su desarrollo y concepción, el paso del paradigma moderno al posmoderno tanto en lo arquitectónico y lo urbano, así como las implicancias de las grandes operaciones relacionadas a las infraestructuras urbanas y los experimentos relativos al programa de uso mixto. Como conjunto, su desarrollo manifiesta el paso en menos de cinco años, de un modelo moderno, ya impuro, de placa y torre residencial + galerías subterráneas en Centro Nuevo, al posmodernismo de Rossi de edificio constructor de ciudad, propio del centro, en Plaza Lyon, que esperaba propiciar la densificación interior de las manzanas conformando entre ambos una infraestructura pública, un único edificio interrumpido por una avenida, cuyo suelo urbano poroso recoge tanto la geometría resultante de la apertura de la Nueva Providencia, como recorridos para un peatón que pasea por un fragmento de ciudad, experimentando distintos modelos y espacios comerciales.
Una sátira biopolítica. Las atmósferas de Hans Hollein en la XIV Triennale di Milano
Authors: Elvira Peña Juan
Published: December 2022

El final de la década de los años 60 fue un momento crítico para los arquitectos que perseguían utopías sociales. El sueño había terminado: la nueva economía de consumo y la crisis ecológica centraban las nuevas preocupaciones sociales. La biopolítica, estudiada por autores como Michel Foucault, estaba cada vez más presente. El impacto psicológico del medio construido sobre el comportamiento humano era objeto de numerosos estudios: el conductismo radical o el control del comportamiento eran temas clave que influían en la producción artística y en la creación de espacios que jugaban con el comportamiento humano. El pabellón Austriennale de Hans Hollein, construido para la XIV Triennale di Milano, no sólo abarcaba su tema principal, "El gran número", sino que —la hipótesis principal del artículo— estuvo especialmente influido por este ‘giro conductual’. De forma satírica y lúdica, el proyecto abrazó los tiempos de crisis, convirtiéndolos en un espacio de crítica social. Este texto analiza el proyecto en términos de sátira arquitectónica, una máquina biopolítica diseñada para crear una experiencia en serie basada en una gratificación producida en masa. Simultáneamente fordista, kafkiano y freudiano, su organización del movimiento, el control de multitudes, los protocolos de estímulo-recompensa y las atmósferas performativas especializadas se organizan en una obra arquitectónica.
Un sistema en perfecto equilibrio. La presencia de la forma-núcleo y la forma-artística en el proyecto A Gandareira, de Carlos Pita y Abraham Castro
Authors: Quintela João
Published: December 2022

El proyecto A Gandareira, de Carlos Pita Abad (A Coruña, 1964 - ) y Abraham Castro Neira (Silleda, 1986 - ), es un claro ejemplo de una arquitectura que nace de la idea de estructura y del propio proceso constructivo. El proyecto consiste en una gran cubierta generada a partir de un conjunto de grandes vigas prefabricadas de hormigón, simplemente apoyadas, lo cual expone un sistema estructural en perfecto equilibrio que aprovecha la fuerza de la gravedad. No hay trucos: lo que vemos es una estructura pura, lo que experimentamos es el espacio construido por ella. Este trabajo de investigación profundiza en el estudio de este proyecto desde su concepción hasta su materialización y trata de establecer una relación con los conceptos de formanúcleo y forma-artística propuestos por Karl Bötticher (Nordhausen, 1806 - Berlín, 1889) y debatidos por Gottfried Semper (Hamburgo, 1803 - Roma, 1879) a finales del siglo XIX. Estos conceptos fueron retomados casi un siglo después por Kenneth Frampton (Woking, 1930 - ) en varias ocasiones, en particular en su libro "Studies in tectonic culture" (1995). El artículo pretende analizar este proyecto desde un punto de vista estructural para identificar no sólo la presencia de estos conceptos, que tradicionalmente han sido pensados por separado, pero también la superposición física y conceptual de ambos en una única entidad que podríamos llamar forma-esencial.
Analysis of the Convolutional Neural Network Model in Detecting Brain Tumor
Authors: Rankins Destiny , Dixon Dewayne A. , Kang Yeona , Kim Seonguk
Published: December 2022

Detecting brain tumors is an active area of research in brain image processing. This paper proposes a methodology to segment and classify brain tumors using magnetic resonance images (MRI). Convolutional Neural Networks (CNN) are one of the effective detection methods and have been employed for tumor segmentation. We optimized the total number of layers and epochs in the model.  First, we run the CNN with 1000 epochs to see its best-optimized number.  Then we consider six models, increasing the number of layers from one to six.  It allows seeing the overfitting according to the number of layers.
No, los antiguos lo sabían bien
Authors: La Cecla Franco , Rodríguez Gabriela , Merlo Romina
Published: December 2022

La historia del punto G masculino es un invento extraño. En este artículo el autor reflexiona sobre la sexualidad masculina juzgada como culpable y patriarcal, sometida a un proceso de despenización (supresión del pene). Trazando contrastes con las civilizaciones antiguas que sabían que el deseo es impulsado por fuerzas profundas que no son comparables con nuestras intenciones.Tanto la moralización como la política del sexo nos han hecho incapaces de comprender que no podemos confinar el deseo a nuestras expectativas “democráticas” y racionales.
‘Dedo-de-moça’ pepper seedlings were produced using basic slag in alternative substrate
Authors: Oza Eduardo France , Vieira Lo Monaco Paola Alfonsa , Monteiro dos Santos Millena , Lopes Rosado Thiago , Rodrigo Krause Marcelo , Alves Garcia Willian
Published: December 2022

Studies related to the use of steel mill slag have become essential, because of the possibility of its use as a component of substrates in the production of seedlings and because this use minimizes the risk of environmental contamination, resulting from inadequate disposal. Thus, the objective of this work was to evaluate the effect of increasing levels of steel slag in substrates composed of soil with tanned bovine manure and sand, on the growth variables and the quality of “Dedo-de-moça” pepper (Capsicum baccatum L.) seedlings. A randomized block design was used with five slag concentrations (0%, 2.5%, 5%, 10% and 20%) and four repetitions. Evaluations occurred at 55 days after sowing, consisting of counting the number of leaves, measuring plant height and collar diameter, quantifying the dry mass of leaves and roots and determining the Dickson Quality Index. Regression models were fitted (P < 0.05) to treatments with increasing levels of steel slag. The addition around 10% of slag to the substrate provided the highest values of growth variables, in seedlings of Dedo-de-moça pepper.
The development of low sugar bitter melon-green tea compound beverage
Authors: Fu Xingzhou , Zhang Rui , Fu Yifan
Published: December 2022

With fresh bitter melon and green tea as main ingredients, xylitol, sucrose and citric acid as auxiliary ingredients, a new cool health tea beverage was developed. The optimum formula of low sugar bitter melon green tea compound beverage was developed by single factor experiment and orthogonal test based on sensory evaluation. The results showed that the optimum formula was as follows: Bitter melon juice was added at 7%, green tea extract was added at 20%, total xylitol and sucrose was 6% (mass ratio 1:1), citric acid was added at 0.2%, and the volume was fixed to 100% with deionized water. The product has light green color, harmonious aroma, moderate acidity and sweetness, and clear texture. The aftertaste is long, with tea polyphenol content of 342 mg/kg, soluble solids of 5.2% and pH 5.8.
Spontaneous vegetation in the horticultural belt of La Plata as host of Thripidae (Thysanoptera) vectors of Tospovirus: Relative risk as an epidemiological component
Authors: Carrizo Paola , Amela García María Teresa
Published: December 2022

Black Death is a virosis caused by the Tomato Spotted Wilt Virus (TSWV), transmitted by thrips, and represents a complex problem since weed hosts for thrips vectors and the virus is accentuated as virus reservoir and vector sustenance. The objective was to generate, from a list of weeds that act as hosts for the four vector thrips species in the horticultural belt of La Plata, a relative risk categorization as an epidemiological component. Between 2000 and 2003, three sites were selected within the horticultural belt of La Plata (Buenos Aires, Argentina) where flowers of 21 weed hosts of Frankliniella occidentalis, Frankliniella schultzei, Frankliniella gemina and Thrips tabaci were sampled monthly (60 in total). For analysis, the sampling results were grouped into three annual seasons, corresponding to the phenology of greenhouse crops in the region. For the four thrips vectors, the abundance of adult thrips and the presence of their larvae were considered using an unsupervised hierarchical cluster analysis and the DGC multivariate mean comparison test to obtain the number of significant groups. From this base grouping, three risk groups (RG) were defined as a source of inoculum for these vectors: high (H), medium (M) and low (L) according to the status of the reproductive host (RH). The groups that emerged were: (H): RH of F occidentalis, (M): RH of F. schultzei and T. tabaci, and (L): RH of F. gemina or non-vector thrips. Periodic survey and early flowering suppression of nine weed species categorized as high risk is proposed. This implies the continuous monitoring of three weed species, to which other companion weeds are added according to the growing season.
Analysis of main botanical characters of 56 Momordica charantia varieties
Authors: Min Ziyang , Li Yongqi , Han Xiaoxia , Zhang Zhuqing , Yuan Zuhua , Hu Xinjun
Published: December 2022

In order to scientifically evaluate the germplasm resources of Momordica charantia in southern China, the diversity, correlation and cluster analysis were carried out on the main botanical characters of 56 Momordica charantia varieties, such as melon length, melon transverse diameter, single melon weight, internode length, stem diameter, leaf length and leaf width. The results showed that the variation coefficients of 7 agronomic characters of 56 Momordica charantia varieties ranged from 8.81% to 19.44%, the average variation coefficient was 14.21%, the maximum variation coefficient of single melon weight was 19.44%, and the minimum variation coefficient of melon cross diameter was 8.81%. The correlation analysis showed that there were correlations among the agronomic traits. The positive correlation coefficient between leaf length and leaf width was up to 0.978, and the negative correlation coefficient between single melon weight and internode length was up to 0.451. The 56 varieties were divided into 3 groups by cluster analysis, of which 92.86% of the materials were concentrated in the first and second groups, and there were only 4 materials in the third group. The results can provide a reference for the cultivation, utilization and genetic improvement of Momordica charantia resources in southern China.
Onion downy mildew severity in no-tillage irrigation under nutrient budgeting and population densities
Authors: Menezes Júnior Francisco Olmar Gervini de , Araújo Edivânio Rodrigues de , Resende Renata Sousa
Published: December 2022

We analyzed the relationship between nutrient (N and K) parceling and population density on the severity of onion downy mildew under no-tillage fertigation cultivation in the conditions of Alto Vale do Itajaí (Barzil). For this purpose, field trials were conducted in the years 2017, 2018 and 2019, in Ituporanga (Barzil). The treatments corresponded to four population densities (300, 400, 500 and 600 mil plants ha-1) subjected to applications of nitrogen (150 kg N ha-1) and potassium (127.5 kg K2O ha-1) distributed throughout the vegetative cycle of the crop via fertigation on a weekly, biweekly and monthly basis, based on the absorption curve of these nutrients for the cultivar Empasc 352-Bola Precoce. In fertigated no-tillage systems, nutrient (N and K) tranches do not influence the severity of downy mildew. The severity of downy mildew increases linearly with increasing population density, especially from 500 mil plants per ha-1.
Effects of different rootstock grafting on yield and quality of cucumber
Authors: Tan Zhanming , Xuan Zhengying , Zhang Juan , Zhu Sasa , Liu Yifei , Xiong Renci
Published: December 2022

In this study, ‘Xinli No. 3’, ‘Shengli rootstock’, ‘Shenli rootstock’ and ‘Shengzhen No. 1’ were used as rootstock, and ‘Jinchun No. 39’ cucumber was used as scion to study the effects of different rootstock on the yield and quality of grafted cucumber, and to select high quality rootstock suitable for cucumber grafting. Different rootstock affected the survival rate, phenology, the height of plant, stem diameter, growth potential, yield and quality of cucumber grafting. Among them, the survival rate of ‘Shenli rootstock’ grafted cucumber is the highest, and the growth of ‘Shengzhen No. 1’ grafted cucumber is relatively the strongest. There was no significant difference in fruit tuber, melon edge, thorn color and pulp crispness between self-rooted seedling (CK) and each rootstock grafting combination. The average yield of ‘Xinli No. 3’ grafted cucumber plot was not significantly different from that of self-rooted seedlings (CK). The length of ‘Shenli rootstock’ and ‘Shengli rootstock’ grafted cucumber was significantly higher than that of self-rooted seedlings (CK), and the length of ‘Shengzhen No. 1’ Grafted Cucumber was significantly higher than that of self-rooted seedlings (CK). The contents of vitamin C and soluble protein of ‘Shengli rootstock’, ‘Shenli rootstock’ and ‘Shengzhen No. 1’ grafted cucumber were significantly higher than those of self-rooted seedlings (CK), and the contents of soluble sugar were lower than those of self-rooted seedlings (CK). Therefore, ‘Shengzhen No. 1’ and ‘Jinchun No. 39’ have strong compatibility with cucumber. As rootstocks, the grafted cucumber plants not only have strong growth potential and high yield, but also significantly increase the content of soluble protein and vitamin C.