bluuebunny/crossref_metadata_2025 huggingface dataset:
METHOTREXATE FOR REBOUND PHENOMENON OF VOGT-KOYANAGI-HARADA IN JUVENILE: A RARE CASE REPORT
Authors: Bachmid Humairah , Eka Hasnah , Anoez Azizah , Fikri Bahrul
Published: February 2024

Introduction: Vogt-Koyanagi-Harada (VKH), an auto-immune disorder driven by melanocyte antigen, is rare in children. The mainstay treatments are corticosteroid and immunomodulators. Methotrexate is one of immunomodulator that widely used due to its effectiveness with minimal side effects.
Case Report: A 9-years-old boy get diagnosed Vogt-Koyanagi-Harada. His best corrected visual acuities (BCVA) were 20/400 in both eyes. Anterior segment examination showed granulomatous uveitis. Posterior segment examination revealed optic disk swelling, Dallen Fuch’s nodule and exudative retinal detachment. We also found poliosis and vitiligo in his lips. He had been previously treated with topical corticosteroids, oral corticosteroids and topical cycloplegics. The dose was tapered every month. After taking medication for 5 months with the last dose oral corticosteroid 16 mg/day and topical corticosteroid every 8 hours, his BCVA recovered to 20/25 RE and 20/40 LE. During the treatment time, the patient discontinued the medication due to parental disobedience and then came with decrease of vision. Based on the consideration of rebound phenomenon and the use of maximum dose of corticosteroids, we consulted the patient to the pediatrician, and decided to give methotrexate as an immunosuppressant. After receiving 15 mg/week of methotrexate for 3 months, inflammation calmed down but unfortunately the vision did not improve.
Discussion: In children, the main treatment for VKH disease is high-dose corticosteroids. Considering the side effects of prolonged systemic corticosteroid therapy, methotrexate become the first line of corticosteroid sparing agent, especially in chronic stage.
Conclusion: Methotrexate can be an effective treatment option for rebound VKH. 
Keywords: Juvenile Vogt-Koyanagi-Harada, Steroid Sparing Agents, Rebound Phenomenon, Methotrexate.
PUPIL CYCLE TIME AND PERIPAPILLARY PERFUSION IN ANGLE CLOSURE GLAUCOMA
Authors: Kamal Muhammad Alfin , Rahmi Fifin L. , Puspasari Denti , Maharani Maharani
Published: February 2024

Introduction and Objective:
One of important roles in the pathogenesis of glaucoma is vascular condition. To enhance glaucoma management, the clinical assessment of ocular perfusion is required. The pupillary light reflex's afferent or efferent pathways may become impaired as a result of pupil cycle time (PCT) elongation. PCT is a simple objective method to measure the function of optic nerve, including glaucoma. The purpose of this study is to evaluate the connection between pupil PCT and peripapillary perfusion.
Methods:
A cross-sectional study from Kariadi Hospital included 26 eyes with angle closure glaucoma and 26 eyes of healthy patients. Complete ophthalmologic examinations, PCT measurements, and OCT peripapillary angiography were performed on each patient. Patients with history of drugs use that can affect pupillary reflexes such as barbiturates, methyldopa, anaesthetics, and antidepressant, and patients with history of glaucoma attack are excluded. The comparisons between the two groups were examined, with a p<0.05 indicating statistical significance.
Results:
The mean PCT of normal subjects was 943,4ms (882,4ms – 993,4ms) and angle closure glaucoma subject was 1789,5ms (1060ms – 4600ms). There were statistically significant difference of PCT value in angle closure glaucoma compared to normal subjects (P<0,05). Peripapillary flow index and peripapillary vessel density in closed angle glaucomatous eyes were lower than normal eyes (P<0.05). There is a significant relationship between PCT with peripapillary flow index and peripapillary vessel density. (P<0,05).
Conclusion:
In angle closure glaucoma, prolonged PCT associated with decreased peripapillary perfusion as shown by decreases in peripapillary flow index and peripapillary vascular density.
SURGICAL OUTCOMES OF STRABISMUS CORRECTION IN LARGE ANGLE EXOTROPIA
Authors: Sadida Rahmah , Ekowati Liana , Saubig Arnila Novitasari
Published: February 2024

Introduction and Objective: Surgery is one of the treatment options for strabismus. The success rates of surgical interventions, as reported in a number of different studies, vary widely. There is no database of surgical outcome in large angle exotropia patient undergoing surgery in Semarang, Central Java.
This study aims to evaluate the surgical outcome of strabismus correction in large angle exotropia in Dr. Kariadi General Hospital.
 Methods: A retrospective study held from the medical record of patients with diagnosis large angle (>50?) exotropia undergoing strabismus correction surgery from January 2020-December 2022 in Dr. Kariadi General Hospital, Semarang. The clinical characteristics: sex, age, angle of exodeviation, amblyopia condition, sensory deprivation, and postoperative alignment were obtained. Surgical outcome measured with follow up of angle deviation in one month dan three months follow up after surgery.
 Result: Totally 59 large angle exotropia patients were obtained with 31 (53%) were woman and 28 (47%) were man, range aged 1 year to 53 years old had preoperative angle of exodeviation 51->85 ?, 6 (10%) had amblyopia, 11(18.6%) had sensory deprivation. By the 3 months post-operative visit, 100% of all patients reported orthophoria.
 Conclusion: This study found the outcome of strabismus correction for large angle exotropia is satisfactory. Two- or three-muscle surgery provides an effective means for treatment of large angle exotropia.
 Keywords: large angle exotropia, exodeviation, strabismus
Characteristics of Patients with Eyelid Laceration in Kariadi General Hospital Semarang
Authors: Padmastrimaya Aderiesta , Erinda Raja
Published: February 2024

Introduction and Objective: Eyelid laceration is one of the most common ocular injuries with complications. This study examines patient characteristics with eyelid lacerations at Kariadi General Hospital Semarang.
Methods: An observational study used medical records data from April 2019 to January 2023. Age, gender, eyelids, grading, area of laceration, mechanism of trauma and injury, canthal and canalicular involvement, associated injury, and surgery were recorded.
Results: From 75 patients, lacerations were more common in men (56, 75%) and ages 16-<50 years (43, 57%). Lacerations occurred in right lower (21, 28%), right upper (17, 23%), right upper and lower (16, 21%), left lower (9, 12%), left upper (8, 11%), and left upper and lower (4, 5%) eyelids. They were mainly medial (52, 69%), lateral (12, 16%), and central (7, 9%). Full-thickness lacerations (58, 77%) outnumbered lamellar thickness (17, 23%). Blunt trauma (63, 84%) was the main mechanism, with motor vehicle accidents leading 30 (40%). Canthal involvement was absent in 41 cases (55%), medial in 29 (39%), and lateral in 5 (7%). Canalicular involvement was absent in 39 cases (52%) and present in 36 (48%). The three most frequent of associated injury of the patients was 16 (21%) subconjunctival bleeding, 12 (16%) orbital hematom, 9 (12%) conjunctival laceration. All patients underwent surgery, with eyelid repair most common (32, 43%).
Conclusion: Eyelid lacerations mainly involved right lower eyelid, medial region, and are full-thickness. Blunt trauma, particularly motor vehicle accidents, was the main cause. Most cases lack canthal or canalicular involvement. Eyelid repair was the most frequent choice of surgery.
CHEMICAL OCULAR INJURY BY POTASS CHEMICAL OCULAR INJURY BY POTASSIUM PERMANGANAT
Authors: Janardi Saraya Amajida
Published: February 2024

Introduction: Chemical ocular injury is an emergency case and commonly occured among children. Alkaline chemical ocular injury is more destructive especially due to saponification.  One of the rare chemical ocular injury is alkaline trauma by Potassium Permanganate (KMNO4).  

 

Case Report: A case of a three-year-old boy patient brought by his mother in emergency department at Cicendo Eye Hospital with severe pain, redness, and swelling of the left eye. Ten hours earlier, the patient was playing and accidentally exposed to KMNO4. Visual acuity of the right eye was 6/6 and the left eye was difficult to examine. Ophthalmological examination revealed superior and inferior palpebra are swelling, KMNO4 adhered tightly on conjunctival tarsal superior, inferior, and conjunctival bulbi inferior until fornix and temporal area. Cornea was hazed and iris shadow test positive so he was diagnosed with Chemical Trauma Ropper Hall grade II OS. Treatment begins with irrigation 2 litres of normal saline until pH 7 along with debridement of KMNO4 from conjunctival tarsal superior inferior and bulbi. The patient underwent installation of transplanted amniotic membrane and debridement under anasthesia.

 

Discussion: Management in the initial phase is irrigation. The definitive therapy requires surgery to speed up the healing process. Complications that often occur are corneal limbal cell deficiency, dry eye, symblepharon formation, secondary glaucoma, and complicated cataracts. 

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Conclusion: Alkali chemical injury is hazardous and can lead to severe vision threatening complications because of saponification. Prompt and aggressive management is required in such cases to give them the best chance of a more favourable outcome.  

 

Keywords: Chemical ocular injury, Potassium permanganate, Chemical burns, Eye trauma
POTENCY OF OCIMUM SANCTUM L EXTRACT OINTMENT ON THE MANAGEMENT PARTIAL-THICKNESS PALPEBRAL LACERATION, IS IT A NOVELTY TO BE CONSIDERED AS AN ALTERNATIVE THERAPY?: REVIEW ON HISTOPATHOLOGICAL CHANGES IN EXPERIMENTAL MODEL
Authors: Rery Muhammad Insanul Kamil , Lubis Rodiah Rahmawaty , Sitepu Bobby Ramses Erguna
Published: February 2024

Introduction and Objective:
Ocimum sanctum extract (OSE) has been shown to have antioxidant, anti-inflammatory, and antibacterial properties which are responsible for wound healing. This study aims to analyze the effect of 5%, 10%, and 15% OSE ointment on changes in collagen density and fibroblast count in Wistar rats with partial-thickness palpebral laceration.
Methods:
Laboratory experimental study with randomized post-test only control group design. The subjects were 30 rats divided into 5 groups: The placebo; Gentamicin 0.3%; OSE 5%; OSE 10% and OSE 15% group. The intervention was administered 2 times/day for 4 days. On the fifth day, the palpebral tissue was obtained to make histopathological preparations and to observe the collagen density and fibroblast count. Data were analyzed using Mann-Whitney, One-Way ANOVA, Kruskal Wallis, and Tamhane test. A p-value <0.05 was assigned to the statistically significant.
Results:
The placebo group revealed loose collagen tissue and OSE 15% and gentamicin group revealed dense collagen tissue. The low fibroblast count was in the gentamicin and OSE 15% group and the highest fibroblast count was in the placebo group with a mean of 19.77±3.29; 22,67±0,73 and 60.9±10.66 cells, respectively. There was a significant difference (p<0.001) in the collagen density and the fibroblast count based on the treatment groups. Posthoc tests revealed differences in the collagen density level and the fibroblast count between the placebo and the whole group.
Conclusion:
There was a significant difference between placebo and all groups of collagen density changes and fibroblast count. There was no difference between OSE 15% and gentamicin both microscopically and statistically.
 
Keywords: Ocimum sanctum L, Extract of Ocimum sanctum L, partial-thickness palpebral laceration, fibroblast cell count, collagen density
Analisis Manajemen Persediaan Barang Dagang dalam Upaya Meningkatkan Kinerja Perusahaan (Studi Kasus pada Penggilingan Padi Bumi Makmur)
Authors: Pratiwi Agatha , Aminah
Published: February 2024

Inventory management is an effort to determine the size of inventory levels and control them effectively and efficiently the inventory of merchandise. This study aims to find out, test and analyze merchandise inventory management in an effort to improve the performance of Bumi Makmur Rice Milling Company for the period January to June 2022. The technique used by the author in further analyzing and finding facts is through merchandise inventory cards with the perpetual FIFO method and the calculation of company profit / loss. The results of the analysis show a significant increase in inventory from January to June 2022. The performance of Bumi Makmur Rice Milling Company as measured using profitability ratio with gross profit margin calculation also increased significantly, although in the second month it experienced a slight decline. Companies are advised to use merchandise inventory cards so that the company can know exactly the stock of inventory in the warehouse.
Dampak Reputasi, Responsifitas, Pemberian Hadiah, dan Rekomendasi terhadap Nasabah yang Berpindah dari BSI ke Bank Konvensional
Authors: Asakdiyah Salamatun , Rachmiani  , Musafir  , Hasim
Published: February 2024

This research aims to investigate the impact of reputation, responsiveness, gift-giving, and recommendations on Brand Switching, especially the movement of customers from Conventional Banks to Bank Syariah Indonesia (BSI). The research method uses multiple linear regression with a Likert Scale to collect data from 100 respondents who are customers from various cities in Indonesia, including Yogyakarta, Gorontalo, and Surakarta. The validity test results show that all variables have a valid correlation with Brand Switching. Multiple linear regression revealed that gifts had the greatest impact, while recommendations had a lower impact. The F test and t-test confirm that reputation, responsiveness, gift-giving, and recommendations simultaneously and partially significantly influence Brand Switching. Even though the Multiple R shows a relationship of 61.7%, the Adjusted R Square of 35.5% indicates that the model does not fully explain variations in Brand Switching. The conclusions of this research provide insight for bank management to improve reputation, responsiveness, and gift-giving strategies to reduce the level of Brand Switching. Future research is recommended to consider additional variables and a qualitative approach to explore the factors that influence customer decisions.
Pengaruh Sistem Pemasaran Hasil Pertanian dan Keterbatasan Penjualan Terhadap Perekonomian Petani
Authors: Prastiwi Julia E
Published: February 2024

This research discusses the influence of marketing and sales strategies on the economy of farmers in Bayem Village, Kasembon District, Malang Regency. This research aims to determine the impact of the agricultural product marketing system on the farmer's economy in Bayem Village, as well as to evaluate the influence of the agricultural product marketing system and sales limitations on the farmer's economy in Bayem Village. The sampling technique used a simple random sampling method with a total sample of 35 farmers in Bayem Village. The data analysis technique used is multiple linear regression analysis. The research results show that marketing strategies have a significant effect on the farmer's economy. This can be seen from the calculation results for the t variable for Marketing Strategy (X1) of 2,933 with a significance value (sig.) or partial p-value of 0.006, which is smaller than 0.05. Therefore, Marketing Strategy (X1) taking into account other variables has a partially significant influence on the dependent, namely the Farmer's Economy (Y). Furthermore, sales also have a significant effect on the farmer's economy, with a t value of the X2 variable of 3.076 and a significance value of 0.004, which is also less than 0.05. This shows that X2 has a significant influence on the dependent variable, namely Y. Overall, marketing and sales strategies together have a significant influence on the farmer's economy. This is confirmed by the calculation results in the Anova F Test of 17,124 with an F test significance (Sig) of 0.000, which is less than 0.05. Therefore, it can be concluded that there is a simultaneous influence of the independent variable on the dependent variable so that H0 is rejected and H1 is accepted.
Pengaruh Reward, Gaya Kepemimpinan dan Budaya Organisasi Terhadap Kinerja Karyawan Pada PT. PLN (Persero) ULP Sampit
Authors: Samalla Vieda , Nasir Moechammad
Published: February 2024

Kinerja karyawan di PT PLN (Persero) ULP Sampit dipengaruhi oleh tiga faktor utama, yaitu budaya organisasi, gaya kepemimpinan, dan reward. Analisis dilakukan melalui serangkaian uji instrumen, uji klasik, dan uji hipotesis dalam survei yang melibatkan responden menggunakan kuesioner. Data yang terkumpul dianalisis dengan menggunakan perangkat lunak statistik SPSS versi 24. Hasil penelitian menunjukkan bahwa (1) reward memiliki dampak pada kinerja karyawan, meskipun tidak signifikan; (2) gaya kepemimpinan juga memiliki dampak pada kinerja karyawan, namun tidak secara signifikan; dan (3) budaya organisasi memiliki pengaruh yang signifikan dan positif terhadap kinerja karyawan.
Pengaruh Sistem Informasi Akuntansi dan Pengendalian Internal Pemerintah Terhadap Kualitas Laporan Keuangan Daerah Pesawaran
Authors: Novriansyah Erwin , Nilwan Afrizal
Published: February 2024

Pesawaran Regency is one of the regions in Lampung that has received the Fair Without Exceptions (WTP) predicate from the Financial Audit Agency (BPK). This research aims to measure the impact of existing variables on the quality of regional financial reports. This research uses a quantitative approach with a purposive sampling method and a Likert scale measurement. Data was collected by distributing questionnaires to 30 respondents, employees of the Regional Financial and Asset Management Agency (BPKAD) of Pesawaran Regency who focus on the financial sector. The research results show that variable X1, namely the accounting information system, and variable X2, namely the internal control system, influence the quality of financial reports. These findings contribute to further understanding regarding the role of accounting information systems and internal control in ensuring the quality of regional financial reports.
Pengaruh Profitabilitas, Likuiditas, Struktur Aset, dan Pertumbuhan Penjualan Terhadap Struktur Modal pada Perusahaan Sektor Consumer Goods Industry yang Terdaftar di Bursa Efek Indonesia Tahun 2019-2022
Authors: Buana David Imam , Karmawan  , Anggita Wenni
Published: February 2024

This research aims to test and analyze the influence of profitability, liquidity, asset structure, and sales growth on capital structure in companies in the consumer goods industry sector. This type of research is quantitative research with a sample of companies in the consumer goods industry sector. The independent variables used in this research are profitability, liquidity, asset structure, and sales growth, while the dependent variable in this research is capital structure. The sample in this study was 32 companies using the purposive sampling technique. The data analysis method used is multiple regression analysis. Based on the results of research conducted with a sample of 32 companies, it can be concluded as follows: (1) The profitability variable has a significant positive influence on capital structure because the company is carrying out expansion which requires a lot of funds to encourage increased profits in the future. (2) The liquidity variable has a significant negative influence on capital structure because sector companies that have high liquidity means they can pay short-term debt, so they tend to reduce total debt, which ultimately will make the capital structure smaller. (3) The asset structure variable does not have an influence on the capital structure because most of the company's fixed assets are financed with the company's internal funds. An increase in fixed assets is not always followed by an increase in long-term debt. (4) The sales growth variable does not influence the capital structure because sales tend not to be supported by an efficient increase in the company's capital, resulting in operational costs that are too high
Analisis Organizational Citizenship Behavior (OCB) dan Work-Life Balance dalam Meningkatkan Kinerja Karyawan Generasi Z di PT Galang Tinggi Raya
Authors: Fajar Gandi Muhammad
Published: February 2024

Every company expects optimal employee performance to support the achievement of the company's main goals. This research aims to explore the impact of Organizational Citizenship Behavior (OCB) and Work-Life Balance on improving the performance of Generation Z employees at PT Galang Tinggi Raya. In addition, this research identifies supporting and inhibiting factors in improving the performance of Generation Z employees at PT Galang Tinggi Raya. This research involved a sample of 5 employees from PT Galang Tinggi Raya. The main approach in data collection is interviews as the primary method. The research results show that the implementation of OCB at PT Galang Tinggi Raya, especially in the aspect of Altruism (providing voluntary assistance to colleagues), has gone well. It was found that providing help to coworkers, both regarding tasks and personal problems, contributed positively to employee performance.
Analisis Pengaruh Kualitas Pelayanan, Nilai yang Diterima, dan Citra Perusahaan terhadap Kepuasan Nasabah Tabungan di PT. Bank Syariah Indonesia (BSI) Kota Sorong
Authors: Irawan Satrya Bayu , Sahetapy Willyan , Nurlela
Published: February 2024

This research aims to analyze the impact of service quality, value received, and company image on savings customer satisfaction at PT. Indonesian Sharia Bank (BSI) Sorong City. The research sample consisted of 177 savings customers selected using the convenience sampling method from the total population of PT savings customers. Indonesian Sharia Bank (BSI). Primary data was collected through questionnaire distribution. Data analysis was carried out using multiple linear regression. Hypothesis testing was carried out partially (t-test) and simultaneously (F test) with a significance level (α) of 5%. The research results show that the independent variables, namely service quality, value received, and company image, significantly influence PT savings customer satisfaction. Bank Syariah Indonesia (BSI) both partially (t-test) and simultaneously (F-test). Of these three variables, service quality is the variable that has the most dominant influence on customer satisfaction at PT. Indonesian Sharia Bank (BSI).
Pentingnya Kualitas Pelayanan dalam Anuitas dengan Tinjauan Financial Highlight Asuransi di PT. Asuransi Umum Bumiputera Muda 1967 Cabang Medan
Authors: Handayani Oktavia , Sari Maya , Nopiazinda Adelia , Anugrah Rizki , Rahayu Sri Ulfa
Published: February 2024

The Importance of Service Quality in Annuities with a Review of Financial Highlights of Insurance at PT. Bumida General Insurance 1967. This research focuses on the importance of service quality in the annuity products offered by PT. Bumida General Insurance 1967. By combining qualitative and quantitative approaches, this study evaluates how service quality affects customer perceptions and company financial performance. The findings show that superior service quality plays an important role in increasing customer confidence and strengthening the company's financial position in the insurance sector. The data analysis technique used is the data triangulation technique, namely testing similar data from various sources. Based on the results of these observations, it appears that the quality of customer service at Bumida General Insurance 1967 Medan Insurance branch is quite good. This is demonstrated by the absence of complaints from customers who remain and do not move to other service companies or insurance companies. Bumida 1967 continues to survive in world competition even though many other insurance companies have emerged that are no less large. Currently, Asuransu Bumida 1967 is still one of the largest insurance companies in Indonesia. However, the quality of service at the Bumida Bersama Life Insurance Medan branch must continue to be improved so that the positive image that has been created can be maintained.
The Role of Green Intellectual Capital Towards Masuliyyah Improving Environmental
Authors: Yudianto Agus , Yuliawati Tuti
Published: February 2024

Environmentally, the company tries to achieve a level of environmental protection as part of the organization's sustainability goals. Meanwhile, socially, companies must also benefit society so that their existence gains social legitimacy. This research examines the influence of Green Intellectual Capital (GIC) towards Masuliyyah Improving Environmental Performance. In its implementation, green intellectual capital consists of Green Structural Capital (GSC), Green Human Capital (GHC), and Green Relational Capital (GRC), which reflect the intangible assets owned by the company, including knowledge, wisdom, experience, and innovation with attention to environmental welfare. This research is related to abstract ideas or theories and is often used to develop new concepts or provide new interpretations of existing theories. Through comprehensive literature analysis, this kind of research can produce research models that can be developed in further empirical research. The role of Masuliyyah green intellectual capital is environmentally friendly sustainability of human capital, the impression felt by organizational elements in their journey to discover and build organizational knowledge and improve the organization's environmental performance by focusing on needs, comfort, and a sustainable environment, but also providing the meaning of learning, innovation, maintaining friendly environment, support and attention to organizational elements to achieve common goals towards masuliyyah improving environmental performance.
Pengaruh Disiplin Kerja, Komitmen Organisasi dan Person Job Fit Terhadap Kinerja Karyawan Pada Sektor Industri Mebel di CV Gardenia Java Ngabul Jepara
Authors: Agustina Sinta , Prawitasari Dian , Oktavia Vicky , Wibowo Mochammad Eric Suryakencana
Published: February 2024

Perusahaan diharapkan mampu memaksimalkan sumber daya manusia yang terbatas yang dimilikinya guna memenuhi tujuan suatu perusahaan yang telah ditetapkan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variabel disiplin kerja, komitmen organisasi, dan person job fit terhadap kinerja karyawan di CV Gardenia Java.  Metode penelitian yang digunakan adalah metode kuantitatif. Objek penelitian merupakan salah satu industri mebel yang ada di Jepara. Populasi dalam penelitian ini adalah karyawan pada bagian produksi dengan jumlah 105 orang. Teknik penarikan data yang digunakan adalah kuesioner. Analisis data dengan menggunakan regresi linier berganda dengan bantuan aplikasi SPSS 25. Dalam menganalisis data menggunakan metode statistik dengan menggunakan uji validitas, reliabilitas, dan normalitas. Untuk memastikan apakah data memenuhi asumsi dasar penelitian maka dilakukan uji asumsi klasik. Selain itu peneliti akan melakukan uji multikolinearitas, heteroskedastisitas, uji T, uji simultan (F), dan uji determinasi.  Hasil dari penelitian ini menunjukan bahwa: (1) Variabel disiplin kerja mempunyai pengaruh positif terhadap kinerja pegawai yang ditunjukkan dengan nilai b1 (nilai koefisien disiplin kerja) sebesar 0.678 yang artinya semakin meningkat disiplin kerja maka kinerja pegawai akan meningkat; (2) Variabel komitmen organisasi mempunyai pengaruh positif terhadap kepuasan kinerja pegawai, yaitu jika komitmen organisasi meningkat maka kinerja pegawai akan meningkat. Hal ini ditunjukkan dengan nilai koefisien komitmen organisasi (b2) sebesar 0.478; (3) Variabel person job fit mempunyai pengaruh positif terhadap kinerja pegawai yang ditunjukkan dengan nilai koefisien person job fit sebesar 0.561 (b3). Artinya jika person job fit menjadi lebih terjangkau maka kinerja karyawan akan meningkat.
Pengaruh Green product, Green Price dan Green Brand Image Terhadap Keputusan Pembelian Produk Galon Le Minerale
Authors: Ulya Salma Novita , Aqmala Diana
Published: February 2024

Tujuan penelitian ini adalah menganalisis pengaruh Green product, Green Price, dan Green Brand Image terhadap Keputusan Pembelian Galon Le Minerale. Data yang digunakan dalam penelitian ini menggunakan kuesioner berbasis Google Form, dan data valid yang berhasil dikumpulkan sebanyak 120 responden. Metode pengambilan sampel pada penelitian ini adalah purposive sampling. Alat bantu pengujian yang digunakan adalah SPSS. Metode analisis pada penelitian ini menggunakan data primer kuantitatif, menggunakan metode penelitian analisis linier berganda, tahap uji yang dilakukan adalah: uji validitas, reliabilitas, regresi linear berganda, uji F, uji t dan koefisien determinasi. Hasil penelitian ini menunjukan bahwa variabel Green product, Green Price, Green Brand Image secara parsial dan simultan berpengaruh positif dan signifikan terhadap keputusan pembelian. Penelitian ini memberikan manfaat signifikan bagi perusahaan galon Le Minerale dengan membuka wawasan mendalam tentang preferensi konsumen terhadap aspek-aspek keberlanjutan, seperti green product, green price dan Green Brand Image. Hasil penelitian ini dapat membimbing strategi pemasaran yang lebih tepat sasaran, memungkinkan perusahaan untuk meningkatkan daya tarik produk, memperluas pangsa pasar, dan membangun hubungan yang lebih kuat dengan konsumen yang peduli lingkungan. Dengan memahami keputusan pembelian konsumen secara mendalam, perusahaan dapat mengoptimalkan upaya keberlanjutan mereka untuk mencapai dampak positif yang lebih besar di pasar.
Analisis Faktor Harga dan Mutu dalam Keputusan Pembelian Konsumen terhadap Sepeda Motor Listrik GESITS di Indonesia
Authors: Aji Achmad Maezar Bayu , Firmansyah Alfian , Macpal Stelly Julia
Published: February 2024

In the development of the electric motorbike industry in Indonesia, this research focuses on the influence of price and quality on vehicle purchasing decisions, especially Gesits electric motorbikes. Manufacturers, facing fierce competition, continue to improve product quality, price and design to meet consumer needs. By involving 52 respondents (25% of the population of 207 units sold), this study exceeds the recommended minimum sample size. The results of multiple linear regression analysis show that price and quality factors have a significant correlation and strongly influence Gesits purchasing decisions. This research contributes to understanding the purchasing factors of electric motorbikes, providing strategic insight for manufacturers in improving quality and pricing.
Analisis Pengaruh Ketersediaan, Kualitas Produk, Promosi, dan Harga terhadap Kepuasan Konsumen Pengguna MacBook di Jakarta Selatan
Authors: Wadu Ruth Mariana Bunga , Wirawan Rio
Published: February 2024

This research aims to analyze the influence of product availability, product quality, promotion, and price on consumer satisfaction with Macbook laptop users in South Jakarta. Through a multiple linear regression analysis approach, this research uses primary data processed using SPSS tools. The results of the validity test show that the research variables are recognized as valid, and the reliability test shows a good level of reliability. VIF analysis confirmed the absence of multicollinearity problems. By using a regression equation, the research results show that product availability, product quality, promotion, and price together influence consumer satisfaction. The individual t-test on these variables produces significant values. Therefore, the hypothesis proposed in this study is accepted. These findings support the importance of promotional strategies in increasing consumer satisfaction and strengthening product positions in the market. The practical implications of this research guide for companies to design more effective marketing strategies, improve product quality, optimize promotions, and design more effective pricing policies to achieve higher consumer satisfaction.
Motivasi Menghafal Al-Qur'an Juz 30 Pada Peserta Didik Kelas VI Dalam Meningkatkan Belajar Baca Al-Qur’an Di Madrasah Ibtidaiah Yamra Merauke
Authors: 'Rudi Hartono
Published: February 2024

This research aims to determine the process of memorization motivation, motivation factors, and achievement results for class VI students in increasing interest in learning to read the Al-Qur'an through motivation to memorize Al-Qur'an juz 30. This research is classified as a qualitative research type, a research approach that used: phenomenological. The data sources for this research are the Head of the Madrasah, the Head of the Al-Qur'an class coordinator, the Al-Qur'an class supervisor and the students. The data collection methods used were observation, interviews and documentation. Then, data processing and analysis techniques are carried out through three stages, namely: data reduction, data presentation, data verification and drawing conclusions. Research results: A. motivation process for memorizing Al-Qur'an Juz 30: 1) Students' self-awareness of learning, 2) Adjusting goals, 3) Learning to students' needs, 4) Giving a gentle touch, 5) Giving gifts, 6 ) Giving praise and respect, 7) Students knowing their learning achievements, 8) A healthy school environment, 9) Competent and humorous teachers. B. Factors that influence motivation to memorize the Qur'an: a) Internal factors, in the form of attitude, personality, education, experience and ideals. b) External factors, in the form of social and non-social environments. C. Student achievement results: 1) can memorize Juz 30 according to the target, 2) can read the Al-Qur'an well and correctly, and 3) master the science of recitation.

Keywords: Al-Qurán, Motivation, Memorizing
Investigation the Relationship Between Myonectin Levels and Both Lipid Profiles and Liver Function Tests in Diabetic Nephropathy Patients
Authors: Ismail Zahraa. M. , Al-Fartusie Falah S. , Tahir Noor. T. , Ismail Ahmed H.
Published: February 2024

Myonectin, or CTRP12, is a relatively recent adipokine—a protein released by adipose tissue that has gained interest in the context of metabolic health, including its possible implications in diabetic complications. Volunteers were divided into three groups, healthy subjects as controls (group A), they don't suffer from any disease, patients with T2D without nephropathy  (group B) and T2D with nephropathy (group C), the age ranges between (35-70) years and the average duration disease of T2D (5-25) years, attending to the AL-Kindi teaching hospital, Baghdad Iraq. There was a highly significant increase P ≤ 0.01 of FBS, Insulin level, HOMA-IR, HbA1c, TC, TG, HDL and TSB among different groups (T2D with nephropathy, T2D without nephropathy, and control), a highly significant increase P ≤ 0.01 of myonectin levels among different groups. There was no significant difference present in AST U/L, and ALP U/L. A statistically significant increase in ALT U/L when compared with the control group. Conclusion: Levels of serum myonectin were significantly higher in patients with (T2D without nephropathy) as compared with ( T2D with nephropathy) and the control group.
Radionuclide Imaging Findings in Iatrogenic Stress in Cases with Reduced Left Ventricular Ejection Fraction
Authors: Ceylan Sule
Published: February 2024

Objective: This study aims to contribute to the existing literature by assisting in the selection of stress protocols for patients with reduced left ventricular ejection fraction (LVEF). We also aim to provide insights into patient follow-up based on changes in post-stress LVEF determined by echocardiography.
Methods: Our retrospective study encompassed 487 patients initially diagnosed with coronary artery disease. Left ventricular function was assessed using echocardiography and myocardial perfusion scintigraphy. Among them, 250 patients with LVEF values within normal limits constituted Group-1, while 237 patients with LVEF values below 50% formed Group-2. Exercise stress testing was performed using a treadmill according to the Bruce protocol. For vasodilator stress testing, intravenous adenosine infusion at a rate of 140 μg/kg/min was administered for 6 minutes. Tc-99m-sestamibi was intravenously administered (8-12 mCi) for stress imaging and (24-36 mCi) for rest imaging.
Results: The median age of all patients in the study was 64 (52-79) years, with 283 (58.1%) being male. Myocardial perfusion, assessed by myocardial perfusion scintigraphy, revealed a fixed perfusion defect in all patients. Reversible perfusion defects were observed in 172 (35.3%) patients. Among patients with reduced echo-LVEF values, those who underwent exercise stress testing showed significantly lower post-stress EF values compared to those who underwent vasodilator stress testing (35 (25-42) vs. 36 (30-47), p: 0.0005). Post-stress LVEF was notably lower in patients with reversible perfusion defects, indicating a higher rate of LVEF decrease due to stress (p: 0.0005).
Conclusion: Left ventricular ejection fraction (LVEF) serves as a valuable metric for assessing left ventricular function. The findings from this study support its utility in guiding the selection of a suitable stress protocol and monitoring patients during iatrogenic cardiac stress applications.
Drug Resistance Tests for Mycobacterium Tuberculosis and Compatibility between Tests; From Past to Today
Authors: Keren Metin
Published: February 2024

Objective: The gold standard for pulmonary tuberculosis diagnosis is the demonstration of Mycobacterium tuberculosis bacilli. Drug susceptibility test results of the bacilli obtained are crucial in tuberculosis treatment management. The various tests used to determine drug susceptibility must yield the same result. In the present study, we aimed to evaluate the compatibility of drug susceptibility test results obtained by Löwenstein-Jensen (L-J) and BACTEC 460TB methods from the past to the present.
Material and Methods: Sputum results from 79 patients suspected of multidrug-resistant pulmonary tuberculosis (MDR-TB) clinically, radiologically, and bacteriologically were evaluated for isoniazid, rifampicin, ethambutol, and streptomycin between June 1997 and June 1998. Culture and drug sensitivity tests on the L-J medium were conducted at the Heybeliada Chest Diseases and Thoracic Surgery Center bacteriology laboratory, while culture and drug sensitivity tests with the BACTEC 460 TB system were performed at another center. The results were assessed for compatibility using the Kappa (κ) test, a tool for comparing two independent parameters.
Results: All drug sensitivity tests for isoniazid, rifampicin, ethambutol, and streptomycin were collectively evaluated. It was determined that 263 (83.3%) of 316 drug sensitivity tests yielded concordant results, while 53 (16.7%) produced discordant results. The drug sensitivity tests using L-J and BACTEC 460TB methods indicated compatibility only for streptomycin (κ = 0.715). In contrast, they yielded different results for isoniazid (κ = 0.585), ethambutol (κ = 0.552), and rifampicin (κ = 0.507). Streptomycin exhibited compatibility, while isoniazid, ethambutol, and rifampicin showed incompatibility between the L-J and BACTEC 460TB methods.
Conclusion: Drug sensitivity tests are pivotal in tuberculosis treatment management. While literature suggests compatibility between L-J and BACTEC 460TB methods, our study revealed incompatibility. Evaluation of drug sensitivities may lead to confusing results. Current practices involving studies in the same laboratory and genetic testing contribute to faster and more accurate outcomes in managing drug-resistant tuberculosis. Genetic tests and reference laboratories remain crucial for antituberculosis drug sensitivity, emphasizing their continued importance.
GENRE DIFFERENTIATION AND SELECTION OF LANGUAGE MEANS IN WRITING SCIENTIFIC ARTICLES
Authors:   Editor-in-Chief of ", Saloeva Kh. R. ,   Science and Innovative Development",   magazine  Ministry of Higher and Secondary Specialized Education of the Republic of Uzbekistan
Published: February 2024

The article deals with the main problems and difficulties faced by the authors in the preparation of scientific articles submitted to the editors of the scientific journal "Science and Innovative Development". It is emphasized that most authors have no idea about the genre differentiation of articles, which becomes the main reason for the wrong choice of presentation style and language tools when writing scientific articles. The article also discusses the concept of "scientific article", its types and criteria by which a scientific article should be divided into types.
Abordagens Cirúrgicas no Tratamento de Doenças Cardíacas: Uma Revisão Atualizada
Authors: Perfeito Guilherme Nakamura , Costa Andressa da Cruz , Carvalho Dannubio Luz de , Barros Pedro Gomes , Silva Simone da Costa
Published: February 2024

Este artigo de revisão aborda as abordagens cirúrgicas no tratamento de doenças cardíacas, destacando os avanços recentes e as implicações para a prática clínica. Na introdução, enfatiza-se a importância do tema, dada a prevalência de doenças cardíacas e os desafios associados ao seu tratamento. A metodologia incluiu uma busca sistemática em bancos de dados científicos, utilizando termos-chave específicos e critérios rigorosos de inclusão e exclusão. Os resultados são sintetizados em tópicos que cobrem a cirurgia de revascularização miocárdica, substituição e reparo de válvulas cardíacas, cirurgia para arritmias e avanços em técnicas minimamente invasivas. Cada tópico discute a eficácia, segurança e desfechos clínicos associados a essas abordagens. A discussão ressalta a importância da avaliação individualizada e considera as limitações e recomendações para pesquisas futuras. A conclusão resume as descobertas, destacando a evolução contínua da cirurgia cardíaca e a necessidade de abordagens terapêuticas integradas e inovadoras. Este estudo fornece uma visão abrangente e atualizada das técnicas cirúrgicas no tratamento de doenças cardíacas, contribuindo para a prática clínica e a pesquisa na área.
Estratégias de Prevenção e Tratamento da Obesidade: Perspectivas Clínicas
Authors: Maia Júlia Cordeiro , Souza Matheus Henrique de Freitas , Torres Lara Maria Cruz , Silva Fernanda Ágata , Marques Natália Gennari da Costa
Published: February 2024

Este artigo oferece uma revisão abrangente das estratégias de prevenção e tratamento da obesidade, enfocando as perspectivas clínicas. A introdução destaca a obesidade como uma preocupação crescente de saúde pública, abordando a complexidade de seus fatores contribuintes. A metodologia incluiu uma estratégia de busca sistemática em bases de dados eletrônicas, com critérios de inclusão e exclusão bem definidos. Os resultados foram agrupados em quatro categorias principais: intervenções dietéticas e atividade física; terapias farmacológicas; cirurgia bariátrica; e abordagens comportamentais e psicológicas. Cada categoria foi analisada quanto à sua eficácia e desafios. A discussão abordou as implicações dos resultados, enfatizando a necessidade de abordagens multifacetadas e individualizadas, além de destacar limitações e recomendações para pesquisas futuras. A conclusão resumiu as principais descobertas, salientando que o tratamento eficaz da obesidade requer uma combinação de várias estratégias, adaptadas às necessidades individuais. Este estudo destaca a importância da integração de diferentes abordagens para o manejo eficaz da obesidade.
Consequências Cardiorrespiratórias do Cigarro Eletrônico: Perspectivas Atuais
Authors: Vasconcelos José Lucas Moura , Silva Bruna de Aquino Morais da , Sousa Ana Sunamita Pereira de , Leite Andressa Karoline Alves , Sandri Alessandra , Araújo Carina Marien , Henrique Caroline Fernanda Alexandre , Solobodziam Claudia , Nascimento Gabriel da Silva , Fritsch Giordana Gregório , Chaves Guilherme Alves , Barth Gustavo Oscar , Cândido Isabella Felisberto , Rubin Izadorah Ferreira de Souza , Cardoso Luisa Kecyane Batista , Rodrigues Nadja Mara Pondé , Gonçalves Kauara Marcelino , Calmon Maria Fernanda Barros Freitas , Polycarpo Rafaela Bollini , Sousa Sara Elem Pereira de , Dias Vanessa Moraes
Published: February 2024

Este trabalho apresenta uma revisão abrangente dos impactos cardiovasculares do uso de cigarros eletrônicos, com base em uma análise crítica da literatura científica disponível. Os resultados destacam uma variedade de descobertas significativas, incluindo efeitos agudos imediatos, como aumento da frequência cardíaca e pressão arterial após o uso de cigarros eletrônicos, bem como potenciais efeitos adversos a longo prazo, como disfunção endotelial e estresse oxidativo. Embora alguns estudos sugiram que os cigarros eletrônicos podem representar uma alternativa menos prejudicial ao tabagismo convencional, ainda há incerteza considerável sobre seus efeitos a longo prazo na saúde cardiovascular. Essas descobertas destacam a importância de uma pesquisa adicional para elucidar os mecanismos subjacentes e informar políticas de saúde pública e práticas clínicas relacionadas ao uso de cigarros eletrônicos.
SÍNDROME DE EKBOM E SUAS IMPLICAÇÕES DERMATOLÓGICAS: EXPLORANDO O IMPACTO PSICODERMATOLOGICO DA ILUSÃO PARASITÁRIA
Authors: Sousa Vitória Amorim Mendonça de , Monteiro Lauren Felipe , Silva Lucimara de Jesus , Araujo Karoline de Sousa , Fonseca Ariella Pereira Martins , Dias Carlos Henrique Rodrigues , Paula Walder Neto da Silva de , Santos Saíza Arian de Souza , Cardoso Murilo de Miranda , Cardoso Ariadiny da Rocha Gouveia , Leite Giovani Araujo , Polizelli Júlia Alves , Rocha Paula Sabrina Martins Gomes da , Maia Amanda Atthie
Published: February 2024

A Síndrome de Ekbom é uma condição psiquiátrica complexa caracterizada por delírios e alucinações persistentes, nos quais o paciente acredita estar infestado por parasitas ou afetado por objetos inanimados. Esta síndrome, também conhecida como neuroderma parasitofobia, é mais comum em mulheres na quinta ou sexta década de vida e está associada a transtornos psicológicos como depressão e ansiedade. Os sintomas incluem sensações de formigamento, coceira e lesões cutâneas causadas pela tentativa de remover os supostos parasitas da pele. O diagnóstico é desafiador e requer a exclusão de infecções reais. O tratamento geralmente envolve o uso de neurolépticos e uma abordagem empática por parte dos profissionais de saúde. A conscientização sobre a Síndrome de Ekbom é crucial para melhorar o diagnóstico precoce, o manejo adequado e o apoio aos pacientes afetados por essa condição.