bluuebunny/crossref_metadata_2025 huggingface dataset:
Breast cysticercosis mimicking malignancy: A case report from Nepal
Authors: Ghimire Prinska , Jha Anamika , Sharma Nisha , Shrestha Mamata
Published: December 2023

Cysticercosis, caused by the larval stage of Taenia solium, is an uncommon parasitic infection typically associated with the central nervous system. Despite its relatively common occurrence in Nepal due to agricultural practices and pig farming, breast involvement in cysticercosis remains an exceptional clinical phenomenon, which we elucidate through a distinctive case report, highlighting the complexities it introduces in diagnosis. A 62-year-old woman presented with a painful lump in her left breast, which raised concerns of malignancy on clinical examination. Mammography and ultrasound further supported this suspicion, revealing an irregular, high-density mass without calcification, and an echogenic rind. To confirm the diagnosis, an ultrasound-guided biopsy was performed, leading to the conclusive identification of cysticercosis through histopathological analysis. This case underscores the importance of considering cysticercosis as a potential diagnosis for solitary soft-tissue lesions, even in regions with a high prevalence of breast cancer. While imaging findings can provide valuable hints, histopathological examination remains the definitive confirmation method. A multidisciplinary approach is crucial, involving clinical, radiological, and histopathological assessments to accurately diagnose and manage such cases. Raising awareness of atypical presentations of cysticercosis is essential for prompt and effective treatment, ultimately leading to improved patient outcomes.
A novel technique of using percutaneous nerve catheter for post-operative analgesia and early mobilization in hand surgeries
Authors: Kamath B. N. J. , Nayak Keerthan R. , Thaleppady Megha , Kamath K. R.
Published: December 2023

Objectives:

The need for the early mobilization of the fingers after hand surgery cannot be overemphasized in the outcome of the patients. In hand surgeries, the open method of blocking the distal nerves at the distal forearm is well-known and practiced in some centers. The same with a closed method has not been practiced or published in the English literature.

Methods:

We performed the technique soon after the surgery when the patient was still under regional anesthesia/general anesthesia. Pain score was assessed using a numeric pain rating scale (NPRS) between post-operative day 1 and day 4 during the finger mobilization. Active metacarpophalangeal (MCP), proximal interphalangeal (PIP), and distal interphalangeal (DIP) joint movements were recorded using a goniometer.

Results:

NPRS improved from 2.88 ± 0.81 at post-operative day 1–1.69 ± 0.48 at post-operative day 4. Similarly, the range of motion of the MCP joint improved from 66.67 ± 12.31° to 82.67 ± 8.877°. The range of motion of the PIP joint significantly improved from 69.38 ± 26.95° to 85 ± 11.55°, respectively. Similarly, the range of motion of the DIP joint improved from 85 ± 11.55° to 69 ± 11.55°. We have not encountered any major complications such as infection, hematoma, or injury to tendons or nerves.

Conclusion:

The percutaneous nerve catheter is an excellent technique in hand surgeries for blocking peripheral nerves, thus providing analgesia and early rehabilitation.
Large intramuscular and parosteal lipoma of the upper limb: A case report and literature review
Authors: Alghamdi Khalid , Alshayie Meshari
Published: December 2023

Although lipomas are the most common benign soft-tissue tumors, the intramuscular type is rare and the parosteal type is even rarer. These types of tumors can present like malignant tumors like liposarcoma. Unlike superficial lipomas, deep lipomas (intramuscular/parosteal) require magnetic resonance imaging to evaluate for and rule out malignant features. We report this patient with giant and mixed types of rarest lipomas (intramuscular and parosteal) that arise from the humeral periosteum and within the brachioradialis muscle with encasement of the radial nerve. We aimed to increase awareness to think outside the box and shed light on this giant, rarest mixed type of intramuscular and parosteal lipomas. Furthermore, it emphasizes the need for careful investigations to rule out malignant tumors like liposarcoma. Finally, many orthopedic oncology centers designate large, deep lipomas as low-grade liposarcoma due to the risk of local recurrence.
Rhino orbital mucormycosis: The new mimicker of neuro-ophthalmic lesions
Authors: Nandi Sunanda , Chougule Pratik , Dam Bikram
Published: December 2023

It was always challenging to start steroids in a suspected optic neuritis case with rhino-orbital mucormycosis being the differentials in the COVID era. A 27-year-old female presented with headache and fever for 1 week, along with sinusitis and both eyes (BE) blurred vision for 2 days. There was history of tingling sensation in both lower limbs with urinary retention previously. History of COVID infection 1 month back. Vision in Right Eye (RE): 20/20 and Left Eye (LE): counting fingers (CF) CF with presence of relative afferent pupillary defect (RAPD) Grade 3. Humphrey Visual field gave a picture of Junctional scotoma with ganglion cell loss noted in BE. Magnetic resonance imaging (MRI) brain with orbit gave a picture of LE optic neuritis with right ethmoidal, sphenoidal sinusitis involving orbital apex making mucor a suspect. MRI spine showed focal myelitis. Patient underwent nasal endoscopy to rule out rhino-orbital mucormycosis following which she was started on intravenous methylprednisolone (IVMP) and vision improved drastically. Hence, a diagnosis of neuromyelitis optica was made. Three doses of IVMP along with a tapering dose of oral prednisolone were given and the patient is still in follow-up with no recurrence reported till now.
Il fait beau aujourd'hui. Contribution à l'approche linguistique des malentendus interculturels
Authors: Kilani-Schoch Marianne , Alamzad Nastaran , Ayllon Patricia , Hauert Christoph , Osei-Bonsu Avita
Published: December 2023

[pas de résumé]
INTERSECTION ARRANGEMENT DESIGN ON SULTAN HAMID II ROAD - GUSTI SITUT MAHMUD ROAD – 28 OKTOBER ROAD – SELAT PANJANG ROAD PONTIANAK DUE TO THE OPERATION OF THE LANDAK PARALLEL BRIDGE
Authors: Lo Oktaviani Chelin , Mukti Elsa Tri , Juniardi Ferry
Published: December 2023

The signalized intersection on Sultan Hamid II Road - Gusti Situt Mahmud Road – 28 Oktober Road – Selat Panjang Road is an intersection in Pontianak city with high traffic problems. The construction of the Landak parallel bridge initially aimed to reduce congestion, but this created an imbalance that caused congestion. This research analyses the performance of the intersection using the 1997 Indonesian Road Capacity Manual method and VISSIM software simulation. Data was collected in the form of intersection geometric data, traffic light cycle time, vehicle speed, and traffic volume taken for three days with a survey tool in the form of CCTV as a recorder at 06.00 - 18.00 WIB. Then, the data collected is processed into the basis of research to calculate the performance of the intersection in existing conditions and develop alternative improvement plans using MKJI 1997 and VISSIM software simulations. In the analysis with the MKJI 1997 method, the North road's service level is LOS C; the East road is LOS C; the South road is LOS B; the West road is LOS F, and the highest degree of saturation is 1.56. Analysis with VISSIM software simulation obtained the level of service of the intersection LOS C. After making alternative changes in cycle time, geometrics, and restrictions on the time of prohibition of passing obtained in alternative 15 with changes from signalized intersections to roundabouts and geometric changes.
Reaction Kinetics of the Autocatalytic Hydrolyses of Alkyl Lactates
Authors: Brauer Sophie , Mastalski Isaac , Murphy Madeline , Hoekstra Benjamin , Monson Lyle , Dauenhauer Paul , Nicholas Christopher
Published: December 2023

Kinetic description of the hydrolysis reaction of alkyl lactates has been limited to acid-catalyzed conditions even though the reverse reaction, esterification of lactic acid with alcohols, has been well studied in the presence and absence of added acidic catalysts. Methyl lactate and ethyl lactate, like most esters, undergo spontaneous hydrolysis in aqueous solution. As the reaction progresses, the generated lactic acid serves to catalyze ester hydrolysis, while the rate of the reverse reaction to form esters increases with the accumulation of acid product. The reaction sequence of lactate hydrolysis can be described in three regimes: initiation/neutral hydrolysis, autocatalytic hydrolysis, and equilibrium. In these experiments, the evolution of lactate hydrolysis was measured for varying temperatures (6°C to 40 °C) and initial methyl or ethyl lactate concentrations (3 to 40 mol%) to quantify the kinetics transition in reaction regimes with time.
On the Dye-Protein Interaction of TMR-Biocytin – Streptavidin Complex: Molecular Simulations and Time-Resolved Fluorescence Quenching
Authors: Yoo Jang Mok , Lee Sujin , Kim Hahkjoon , Rhee Young Min
Published: December 2023

The interaction of a fluorophore and a protein, as a type of chemical-protein interactions (CPIs), is important toward studying physical properties of a protein through spectroscopy. For example, the structural changes of a protein can often be followed with spectroscopic tools by utilizing such an interaction. Streptavidin-bound 5-(and-6)-tetramethylrhodamine (TMR) biocytin is one of the few systems with which CPI can actually be observed via the fluorescence of TMR. While it has been suggested that the fluorescence is quenched when the ligand is bound to the binding pocket of streptavidin and is recovered after biotin occupies the binding pocket to replace TMR, no clear evidence has been provided yet. In order to gain a better understanding of this CPI, here we propose a possible binding site of TMR in the streptavidin, and predict the binding affinity values of biotin and the TMR moiety of TMR-biocytin conjugate. We estimate that the biotin affinity (-20.2 ± 1.4 kcal/mol) is significantly higher than the TMR-biocytin affinity (-6.91 ± 0.72 kcal/mol and -8.06 ± 0.79 kcal/mol), which supports the earlier explanation on the fluorescence quenching and recovery of biotinylated dyes. We also discover that TMR cannot bind to the streptavidin pocket as perfectly as biotin does, but that it rather blocks the entrance portion of the binding pocket. Fluorescence quenching of TMR-biocytin by streptavidin is measured with time-resolved fluorescence to show that the average fluorescence lifetime of TMR-biocytin decreases from 3.54 ns to 2.54 ns in the presence of excess streptavidin. Based on the distance between TMR and the nearby tryptophan residues, we propose that the nearby tryptophan residues of streptavidin are the potential quenchers of the dye unit fluorescence.
A guidebook for sustainability in laboratories
Authors: Freese Thomas , Kat Renate , Lanooij Suzanne D. , Böllersen Tanja C. , De Roo C. Maurits , Elzinga Nils , Beatty Meagan , Setz Brian , Weber Roza R. , Maltagliati Irene , Gandek Timea B. , Fodran Peter , Pollice Robert , Lerch Michael M.
Published: December 2023

This guidebook aims to improve lab users’ everyday practices to become more sustainable. Specifically, this guidebook provides practical suggestions on how to effectively use lab instruments and resources and on how to acquire data. We provide advice to labs covering disciplines such as biology, chemistry, computational science, engineering, life sciences, materials sciences, medicine, pharmacy, and physics. As every lab is different, it may occur that alternative measures are required, advice may be outdated or not applicable, and sometimes laboratories may not be able to comply with measures of other laboratories.
Model of the location system for transport
Authors: Budko Vladyslava , Popova Anastasiia , Tolstoluzka Olena , Tolstoluzkyi Yevhen
Published: December 2023

In the modern world, tracking systems are actively implemented in various forms, ranging from smart surveillance cameras and integrated smart home systems to tracking parcels, passenger vehicles or vehicles carrying important cargo. This topic is actual for the companies working with vehicles, such as insurance companies, emergency services, and car fleets where tracking the vehicles becomes the commercial necessity. It also concerns those who prefer to work on a rotational basis and have contractors on wheels, for example mining companies, where it is important to track accurately the location of vehicles and calculate the route time. The tracker is a small device used to determine the location and track it. Nowadays, due to its unique properties, this device has a wide range of implementations such as monitoring of children and the elderly, creating optimal routes for the movement of goods using car navigators and video recorders, or ensuring the safety and accuracy of movement of private and commercial vehicles. These small electronic devices can not only determine their coordinates using GPS satellites, but use the built-in communication module to send them to a remote server for further database storage and processing. The currently popular cloud services can be used as a remote server, for instance, Amazon Web Services, the computing power of which is distributed in many geographic locations all around the world, and therefore, it is possible not only to save the obtained data in the geographic location closest to the user, but also to perform their analysis and processing without renting a separate physical server.
НЕКОТОРЫЕ НЕСТАЦИОНАРНЫЕ ДВУМЕРНЫЕ ТЕЧЕНИЯ ГАЗА, ОПРЕДЕЛЯЕМЫЕ С ПОМОЩЬЮ ТРИГОНОМЕТРИЧЕСКИХ РЯДОВ
Authors: Баутин С. П. , Карелина О. А. , Обухов А. Г.
Published: December 2023

В работе используется методика представлений решений системы нелинейных уравнений движения в виде бесконечных тригонометрических рядов от двух пространственных переменных. Коэффициенты рядов являются искомыми функциями от времени, для которых выписана бесконечная система обыкновенных дифференциальных уравнений. Начальные данные задаются в виде конечных тригонометрических сумм. Приближенные решения поставленных задач Коши также строятся в виде конечных отрезков тригонометрических рядов. При различных начальных данных в работе рассмотрены конкретные нестационарные двумерные периодические по пространственным переменным ,  течения газа и проанализированы их свойства.
Advantages and Development Prospects of Building Information Modelling (BIM) Technology Application in Highway Engineering
Authors: Wang Hongmei , Lin Ying , Gan Xiaolin
Published: December 2023

Based on the advantages of the application of Building Information Modelling (BIM) technology in highway engineering, this paper analyzes the difficulties of its in-depth application, grasps the pain points of the application of BIM technology in practice, and approaches from the integration of BIM design-construction. This paper also puts forward the integration of cross-stage information based on the BIM + Geographic Information System (GIS) construction information management system to realize the BIM whole life cycle management, and provides directional support for the continuous and efficient application of BIM technology in engineering practice.
Examining the Pathological Diagnostic Impact of Frozen Sections in Breast Cancer
Authors: Shen Ying
Published: December 2023

Objective: To analyze the diagnostic value of frozen section pathology in the diagnosis of breast cancer. Methods: A total of 50 patients with breast tumors treated between July 2021 and February 2023 were randomly selected as samples. Both paraffin section and frozen section diagnoses were conducted. The paraffin section results served as the gold standard for evaluating the value of frozen section examination. Results: Among the frozen section diagnoses, 48 cases (96.00%) were confirmed, 1 case was misdiagnosed (2.00%), and 1 case was delayed (2.00%). Among the confirmed patients, 45 cases (90.00%) were entirely consistent, and 3 cases (6.00%) were basically consistent. The diagnostic rate of the frozen section was 96.00%, compared with 100.00% for the paraffin section (P > 0.05). The diagnostic time of the frozen section (35.25 ± 2.11 min) was significantly shorter than that for the paraffin section (6911.36 ± 58.36 min; P < 0.05). Conclusion: Frozen section diagnosis is rapid and demonstrates relatively high diagnostic accuracy. It can guide doctors in determining whether to pursue breast-conserving treatment and aid in selecting appropriate surgical methods. This is beneficial for preventing unnecessary medical interventions and reducing the need for secondary surgeries in breast cancer patients.
Assessing the Effectiveness of Montelukast Sodium in Managing Pulmonary Infections in Lung Cancer Patients
Authors: Xu Rui , Wang Li , Huang Zhuan , Zhang Yurong , Huang Lingjuan
Published: December 2023

Objective: To investigate the efficacy of montelukast sodium in the treatment of lung cancer patients with pulmonary infections. Methods: A total of 330 patients diagnosed with lung cancer and pulmonary infection, who were admitted to the First Affiliated Hospital of Xi’an Medical University from 2020 to 2022, were selected as research subjects. They were randomly divided into two groups: a control group receiving conventional treatment and an observation group receiving conventional treatment combined with montelukast sodium. Each group consisted of 165 cases. The time required for clinical symptom improvement, the resolution of lung infection signs, and the levels of serum inflammatory factors before and after treatment were compared between the two groups. Results: The observation group exhibited significantly faster improvement in clinical symptoms compared to the control group (P < 0.001). ELISA assays were conducted to detect the expression levels of IL-1β, IL-6, IL-8, and TNF-α in the serum of both groups at 1 week and 2 weeks into the treatment. The results indicated that, as the treatment progressed, the observation group displayed significantly lower levels of the four serum inflammatory factors compared to the control group (P < 0.001). Conclusion: Montelukast sodium demonstrates efficacy in the treatment of patients with lung cancer complicated by pulmonary infections. These findings suggest its potential for further verification and clinical application.
A Study on Enhancing Pancreatic Islet Function in Type 2 Diabetes and Coronary Heart Disease Patients with Liraglutide and Metformin Combination Therapy
Authors: Yang Chunxiao
Published: December 2023

Objective: To investigate the impact of combining liraglutide with metformin on the enhancement of pancreatic islet function in patients with type 2 diabetes and coronary heart disease. Methods: 60 patients with type 2 diabetes and coronary heart disease admitted from February 2022 to August 2023 were selected as research subjects. They were randomly assigned to either control or treatment groups, with 30 patients in each. The control group received metformin alone, while the treatment group received liraglutide in combination with metformin. Various indicators, including blood sugar levels, pancreatic islet function, and cardiac function between the two groups were compared. Results: The results of FPG, 2hPG, HbA1c, HOMA-IR, NT-proBNP, and LVEDD in the treatment group were lower than those in the control group, whereas the values of FINS, HOMA-β, E/A, and LVEF in the treatment group were higher than those in the control group (P < 0.05). Conclusion: The use of liraglutide in combination with metformin significantly benefits patients with type 2 diabetes and coronary heart disease. It leads to improved pancreatic islet function, better blood sugar control, and enhanced cardiac function. This combination therapy is recommended for clinical adoption.
MEDIA YOUTUBE TERHADAP HASIL BELAJAR IPA MATERI GRAVITASI BUMI KELAS IV SEKOLAH DASAR
Authors: Aisyah Fara , Srinana Wardani Imas , Juniarso Triman
Published: December 2023

Studi ini adalah bentuk respons terhadap hasil belajar siswa yang masih rendah saat aktivitas pembelajaran. Kurangnya suasana pembelajaran yang menyenangkan akan dapat mempengaruhi hasil belajar siswa. Guru menggunakan metode pembelajaran konvensional dan menggunakan media power point, sehingga para siswa cenderung bosan dan kurang memperhatikan penjelasan materi yang disampaikan guru. Studi ini dilakukan sebagai upaya mengidentifikasi dampak dari media youtube pada hasil pembelajaran IPA materi gravitasi bumi kelas IV sekolah dasar. Studi ini termasuk dalam kategori eksperimen semu (quasi-experimental) dengan posttest only control group design serta mengadaptasikan pendekatan kuantitatif. Para siswa kelas IV A dan IV B di salah satu Sekolah Dasar yang berada di Surabaya dengan jumlah 20 siswa pada tiap masing-masing kelas. Data dan informasi yang dipakai didapat melalui observasi serta tes. Berikutnya data akan dianalisis dengan mengimplementasikan beberapa teknik pengujian statistik yaitu normalitas homogenitas, serta pengujian hipotesis menggunakan uji t. Digunakan posttest only control group design dengan menggunakan software SPSS versi 22. Temuan analisis yang dilakukan memperlihatkan jika perolehan nilai t hitung atau data post-test kelas eksperimen dan post-test kelas kontrol hasil belajar siswa signifikansi < 0,05 dengan nilai sig (2-tailed) sebesar (0.019). Dapat disimpulkan bahwa terdapat pengaruh yang signifikan pada penggunaan media youtube terhadap hasil belajar IPA materi gravitasi bumi kelas IV Sekolah Dasar.
Concept Attainment Model for Enhancing Conceptual Understanding in Seventh-Grade Students at Junior High School
Authors: Haq Firjon Nurisna Hadi Al , Walida Sikky El , Sari Fadhila Kartika
Published: December 2023

This research aims to describe the implementation of the Concept Attainment Model in teaching conceptual understanding of quadrilaterals, specifically parallelograms and rectangles. The research subjects were 22 students from grade VII. This study was conducted through two cycles of classroom action research. Each cycle consisted of planning, acting, observing, and reflecting stages. Data collection techniques included observation, concept understanding tests, and interviews. The research results showed that the test scores in cycle 1 and cycle 2 were 67.8 and 78.68, with an increase of 10.88, and the average percentage of students who met the Minimum Mastery Criteria in Cycle 2 was 77.27%. The teacher's success rate in conducting activities in cycle 1 and cycle 2 was 59.54% and 79.54%, respectively, indicating a 20% improvement. Meanwhile, the percentage of students' activity observation results in cycle 1 and cycle 2 was 59.58% and 78.75%, respectively, showing a 19.78% improvement.
Legal Protection of Patient's Electronic Medical Record: Indonesian Legal Perspective
Authors: Basani Christin Septina
Published: December 2023

Health is the most fundamental factor of every citizen, particularly in Indonesia. Considering that many people need health services, patients’ data are pivotal as they contain patients’ health and medical records, identity, examination, medication, and other services patients receive in health services. Medical record in Indonesia is regulated by the Minister of Health Regulation No. 269 of 2008 on Medical Record and the Minister of Health Regulation No .22 of 2022 on Electronic Medical Record. The transition to electronic medical records is expected to finish on 31 December 2023. Electronic Medical Records (EMRs), which are now being implemented across the healthcare system in Indonesia, have the potential to fulfill the rights of citizens in the healthcare sector. On the other hand, data security for patients requires protection, as electronic systems may be vulnerable to data breaches and misuse by unauthorized individuals.  The objective of this research is to examine the legal protection for patients when their electronic medical record data is misused and to elucidate patients' rights in the realm of healthcare, particularly concerning medical records. The research employs a normative juridical approach with a legislative regulation focus. Article 29 of Minister of Health Regulation No. 22 of 2022 already addresses data protection for patients' personal information, although continuous monitoring of the implementation of patient's Electronic Medical Records is still necessary. The findings of this study emphasize the necessity of ensuring data protection guarantees for patients stored within electronic systems.
The Socio–Juridical Dimensions of Passing Off in Indonesia
Authors: Baso Fatihani , Djaoe Andi Novita Mudriani , H Redita Septia Sari
Published: December 2023

There are many business actors marketing products that resemble well-known brands in Indonesia. To prove whether the Passing Off phenomenon occurs or not in Indonesia, the authors use The Classical Trinity Theory. The article’s aim is to explain the socio–juridical dimensions of passing off in Indonesia. Seeing that in Indonesia there are many business actors marketing products that resemble well-known brands. To prove whether the Passing Off phenomenon occurs or not in Indonesia, the author uses The Classical Trinity Theory. The research uses a juridical-normative method, with statute and conceptual approach based on literature study, analyzed qualitatively. The Classical Trinity Theory is a theory used as a basis for assessment which states whether a passing-off action occurred or not. First, Goodwill, is whether business actors use the reputation of well-known brand owners to support their business. Second, misrepresentation, there is confusion by consumers regarding genuine products and fake products. Third, damage, there is an element of deceptive branding and goods or services which could very well result in losses experienced by the owner of the well-known brand as a result of copying the company's identity.
Həkim-Pediatrın Təcrübəsində Probiotiklərin Rolu
Authors: Hidayatova L.A.  , Taghizada T.G.  , Mammadova F.M  , Hajiyeva U.K.  , Hasanova N.S.  , Safarova İ.A.
Published: December 2023

Ədəbiyyat icmalında fizioloji və patoloji proseslərin inkişafında bağırsaq florasının və probiotiklərin rolunu əks etdirən müasir məlumatlar əks olunmuşdur. Burada probiotiklərin təsir mexanimzləri və müxtəlif xəstəliklərin müalicəsində onların rolu göstərilmişdir. Eyni zamanda probiotiklərin tərkibi, təsnifatı, eləcə də onların pozitiv və neqativ təsirləri təsvir olunmuşdur.
Tibbi Etika Və Deontologiyanın Tarixi Məgamları
Authors: Taghizada T.G.
Published: December 2023

Etika, fəlsəfənin ən qədim sahəsi olaraq həkimlərin gündəlik fəaliyyətində rastlaşlıqları çox vacib problemlərindən biridir. Muasir anlayişda: ailədə, cəmiyyətdə, məişətdə, iş yerində insanların münasibətini, davranışını və gətiyyətini müəyyinləşdirməkdən bəhs edir.Həkimlik ixtisası sahəsindəki mənəvi problemlər yeni deyil. O, çox gədim dövrəlrdən cəmiyyəti maraqlandıran, onun diqqətini cəlb edən məsələdir, çünki təbabət insanlara məhəbbət və şəfqət üzərində əsaslanaraq həmişə huminzm ilə əlaqələnmişdir.
Bakı şəhərində göstərilən narkoloji xidmətinin xarakteristikası
Authors: P.P.Mammadov
Published: December 2023

Hal-hazırda Azərbaycan Respublikasının «Narkotik vasitələrin, psixotrop maddələrin və onların prekursorlarının dövriyyəsi haqqında» [5,6] və «Narkoloji xidmət və nəzarət haqqında» [3, 4] qanunları əhaliyə narkoloji yardımın göstərilməsi qaydasını müəyyən edir. Azrbaycan Respublikasının «Narkoloji xidmət və nəzarət haqqında» qanununun 5.6 maddəsinə əsasən, narkotik asıllıqdan müalicənin anonimliyinə dair zəmanət xəstələrin dövlət narkoloji mərkəzlərinə müraciətinin sayının artmasına və narkomaniyanın gizlilik dərəcəsi səviyyəsinin azalmasına səbəb olmuşdur. Hal-hazıradək, Respublika höküməti tərəfindən bu cür yardım qaydasını və onun əlçatan olmasını müəyyən edən müvafiq qərarlar qəbul edilmişdir.
Активный вариант синдрома кандинского-клерамбо при шизофрении
Authors: Асадов Б.М.
Published: December 2023

В последние годы появился ряд исследований, посвященных изучению осо­бен­ностей становления, формирования, психопатологического строения и специфической но­зо­логической окраски синдрома Кандинского-Клерамбо [1; 2; 6; 9 и др.]. Однако, анализ психиатрической литературы показывает, что большинство исследований проведено в плане расширения нозологических форм психозов, в рамках которых встречается синдром Кандинского-Клерамбо, нежели в плане глубокого клинико-психопатологического исследования этого сложного психопатологического состояния. В то же время, в структуре самого синдрома обнаруживаются психопатологические особенности, не ставшие еще предметом специального исследования.

Актуальность исследования. В последние годы появился ряд исследований, посвященных изучению осо­бен­ностей становления, формирования, психопатологического строения и специфической но­зо­логической окраски синдрома Кандинского-Клерамбо [1; 2; 6; 9 и др.]. Однако, анализ психиатрической литературы показывает, что большинство исследований проведено в плане расширения нозологических форм психозов, в рамках которых встречается синдром Кандинского-Клерамбо, нежели в плане глубокого клинико-психопатологического исследования этого сложного психопатологического состояния. В то же время, в структуре самого синдрома обнаруживаются психопатологические особенности, не ставшие еще предметом специального исследования.
Giant Fungating Borderline Phyllodes Tumor of the Breast
Authors: Makhandule F. C. , Bhuiyan M. M. Z. U.
Published: December 2023

Phyllodes Tumors are rare fibroepithelial neoplasms of the breast, accounting for less than 1% of all breast neoplasms. Preoperative diagnosis of Phyllodes Tumors is not easy, and a definitive diagnosis depends on a complete excision of the tumor. We present a case of a Giant Fungating Borderline Phyllodes Tumor of the breast. The main objective is to share our experience with the Phyllodes tumor of the breast from Mankweng Academic Hospital, Limpopo, South Africa. Case Report:  A 50-year-old postmenopausal patient presented to our Breast Oncology clinic with a history of a slow-growing left breast mass for a duration of more than 1 year. It started as a small mass and progressively increased in size. She previously had two core needle biopsies, of which both histological analyses were inconclusive. In the last four months, there were multiple ruptured round masses associated with pain, bleeding, and an offensive discharge. The patient does not have any family history of breast cancer. On examination, the left breast has a fungating mass of 15×15 cm, with areas of necrosis and hemorrhage. There were no associated axillary lymph nodes and no abnormal findings in the right breast. Chest X-ray: normal. A mammogram was not done owing to the fear and risk of bleeding. A mastectomy was performed, and it was a highly vascularized mass. The excised specimen weighed 2.7 kg and was sent for histological assessment, which showed features of fibroepithelial proliferation consistent with Borderline Phyllodes Tumor with areas of stromal atypia, focal increase in cellularity, mitosis 5 per 10 High Power Field (HPF), and clear surgical margins of 0.9 millimeters (mm). The patient was reviewed six weeks after the operation. Conclusion: Owing to the rare nature and misdiagnosis of Phyllodes tumors, it is important to obtain a tissue biopsy for histological assessment of all suspicious breast lesions, regardless of age. Doi: 10.28991/SciMedJ-2023-05-02-04 Full Text: PDF
Jurassic and Cretaceous transgressive-regressive (T-R) cycles, Northern Gulf of Mexico, USA
Authors: Mancini Ernest A. , Puckett T. Markham
Published: December 2023

Establishment of a chronostratigraphic framework is fundamental to the correlation of strata and for the interpretation of the geohistory of a basin. For the onshore basins in the northern Gulf of Mexico, an integrated sequence stratigraphic and biostratigraphic approach has utility as amethod for establishing such a framework. Eleven transgressive-regressive (T-R) cycles and numerous biozones are recognized in Jurassic and Cretaceous non-marine, coastal and marine shelf strata of basins of the northern Gulf ofMexico. The cycles consist of a transgressive phase (aggrading and backstepping intervals) and a regressive phase (infilling interval). Cycle recognition is based on stratal geometries, the nature of the cycle boundaries, facies stacking patterns and large-scale shifts in major facies belts. Cycles are primarily controlled by the change in accommodation space resulting from stratigraphic base-level changes (eustatic and tectonic effects) and sediment supply. Utilizing this integrated approach, 12 regional unconformities and 11 surfaces of maximum transgression (regional marine flooding surfaces) were identified as major events in the Mesozoic geohistory of the northern Gulf of Mexico region. The surfaces of maximum transgression have potential as events for chronocorrelation.
Caracterización y función del Weya'weya en algunos relatos de tradición oral de los zoques de Chiapas
Authors: Velasco Estrada Jaime
Published: December 2023

En el presente trabajo se estudia el relato del Weya’weya, a partir de la caracterización y de la función que desempeña el personaje en las comunidades zoques. El análisis tiene como base distintas versiones del relato recogidas en Chiapas. Si bien el relato del Weya’weya ha pervivido en las narraciones orales con diferentes caracterizaciones, por lo general su función se mantiene estable, gracias a que el relato se ritualizó (y en ese sentido, adquirió fijeza) en la danza homónima. A grandes rasgos, puede decirse que representa una especie de héroe en quien recae los valores colectivos. Versión a versión, se ha intentado rescatar los distintos y complementarios elementos que encarna: de ser un ente sobrenatural relacionado con la de fertilidad y el mundo primitivo, en su ‘actualización’ y ‘re-funcionalización’ católica, en cierto modo, se convirtió en símbolo de fortaleza ascética, se transfiguró en San Juan Bautista.
El emprendimiento. Reto de la educación superior ante el mercado laboral global y flexible
Authors: Lladó Lárraga Dora María , Espinosa Barajas Jeny Haideé , Leal Ríos Fernando
Published: December 2023

La presente comunicación tiene como propósito presentar un panorama sobre las razones por las que en el contexto actual se hace necesario impulsar una formación emprendedora, especialmente en el estudiantado del nivel superior.  La primera parte del escrito presenta cómo las transformaciones económicas, políticas y tecnológicas de las últimas décadas impactan en los mercados de trabajo transformando los procesos laborales y organizativos, formas de organización laboral y productiva interna y externa, mecanismos de contratación y permanencia del personal y servicios. Ello genera demandas a las instituciones de educación superior con relación a la identificación de las competencias demandadas a los profesionistas en el contexto de los mercados de trabajo flexible. Se pone de manifiesto que ante la falta de oportunidades de empleo en este contexto global y ante el continuo tránsito de condición laboral -que va de la dependencia a la independencia o viceversa- en el mercado de trabajo, el emprendimiento comienza a vislumbrarse como una oportunidad para lograr el autoempleo, es decir la propia generación de trabajo.
Breaking the Ice: Exploring the Link Between Glaciers and Mental Well-being
Authors: Beausoleil Keeya , Moon Judy , Mah Rowan
Published: December 2023

Background    Glaciers are integral in maintaining hydrological cycles, moderating oceanic levels, and preserving valuable ecosystems.  Cryospheric regions are often overlooked in evaluating the environmental factors affecting mental health. This study investigates the potential influence of glacial presence and melt behaviour on global mental health, particularly among marginalized communities.
Methods   National suicide rates of general population and specific age categories were gathered from World Health Organization between 2012-19. Glacial data was sourced from the World Glacier Monitoring Service, and Randolph Glacier Inventory. Wilcox testing was conducted to identify mean suicide rates across countries with and without glaciers. Pearson and Spearman correlation testing were employed to identify relationships between melt rate indicators and suicide rates.  
Results    Over the entire eight-year duration, countries with the existence of glaciers revealed a notably higher suicide rate (p-value of 0.0001). Children aged 5-15 years old demonstrated a consistently higher suicide rate amongst countries with glacial bodies (p-value between 0.020-0.037). A positive correlation between regional suicide rates and glacial area was revealed, except in low-latitude countries.  Although melt rate variability showed no significant correlation with suicide statistics, Greenland was the only country to demonstrate a negative relation among all populations.
Conclusions    To address the ongoing impacts of the climate crisis, further research is necessary to develop an inclusive framework that acknowledges the unique challenges faced by communities living in cryospheric regions.  This study is the tip of the iceberg, recognizing the importance of inclusivity in addressing the mental health implications of climate change in these environments.
Waqf-based private forest management model: case study in Bogor Regency, Indonesia
Authors: Restiyani Destika , Hardjanto  , Hasanah Neneng
Published: December 2023

As in Bogor Waqf Forest, a waqf-based private forest management pattern was developed in Indonesia. Waqf currently functions not only for constructing mosques, cemeteries, and orphanages, but also for environmental preservation, known as green waqf. This study analyzed the mechanism of waqf forest development and waqf forest management practices in Bogor Regency. The method used Exploratory research was conducted using primary and secondary data. The informants were selected using purposive sampling. The data were analyzed qualitatively. The results showed that Bogor Waqf Forest Foundation collected donations in the form of zakat, infaq, and waqf (ziswaf) for the development of the Bogor Waqf Forest. In addition, the Bogor Waqf Forest Foundation collaborates with BAZNAS and the Ministry of Religious Affairs to manage Bogor Waqf Forest productively by empowering local communities by forming groups such as the Berkah Bersama Group, Giat Bersama Group, Citra Berdikari Group, KUB Asri Berseri, and Kelompok Tanggap Bencana (KATANA). Bogor Waqf Forest Management applies agroforestry forest management practices, such as agrosilvofishery, agrosilvopasture, apiculture, and agrisilviculture, which are non-timber product-oriented, namely NTFPs and environmental services.
Chikungunya: Diagnostic, Treatment and Challenge in Indonesia
Authors: Ramzi Ali
Published: December 2023

Chikungunya based on the literature is classified as one of the many diseases that become a differential diagnosis of acute undifferentiated fever. Finally, patients with this condition are treated with empirical therapy so that often the management does not meet the standards / undertreatment. In an effort to reduce morbidity and improve the quality of care with limited modalities, history taking and physical examination as well as effective risk factor analysis are necessary in the current situation in Indonesia. Therefore, the authors raise this topic to help improve diagnostic acuity and the importance of the role of laboratory modalities in the diagnosis of chikungunya in Indonesia. Google Scholar by using the search keywords "Chikungunya" and "In Indonesia" with a time span of 2013-2023. Through a search that has been carried out using these 2 keywords, we get 10,300 publications. Based on the inclusion and exclusion results, 30 publications were obtained that could be used in compiling our literature review. Indonesia is an archipelago and is one of the countries in the world with a tropical climate, so it is certainly an ideal place for various tropical infectious diseases such as chikungunya. Although Indonesia has suppressed chikungunya incidence, Indonesia still facing some problem on diagnostic and case reporting system. This situation effect the performance of incidence validity and quality of treatment.  Chikungunya virus infection in Indonesia still requires diagnostic development efforts to anticipate future outbreaks.
Effectiveness of Plant Bioactive Compounds as Colorectal Cancer Cell Line Inhibitors: A Systematic Review
Authors: Fadillah  , Rahmi Aulia , Rahman Aldi Tamara , Annisa Nurul , Ibrahim Muhammad Hamdi , Aisyah Rihadatul , Irwan Reziq Marchellino , Maliza Rita
Published: December 2023

Cancer is a non-communicable disease and one of the highest causes of human death. It has been well documented that active substances have been shown in vitro to have anticancer properties. The purpose of this article is to examine the therapeutic implications of active substances involved in colorectal anticancer activity. We looked through the databases of PubMed, Science Direct, and Google Scholar in our systematic review to find papers released between 2013 and 2023. Ten studies were selected and published between 2013 and 2023. From the results obtained on plant data used as colorectal anticancer, it was reported that plants contain active phenolic compounds, flavonoids, alkaloids, gallic acid, saponins, triterpenoid/steroid, hydroquinones, triterpenoids, phenols, glycosides, quercetin, kaempferol, artemisinin, and tannins that can act as colorectal anticancer agents and are proven to be an inhibitor of cell line growth in colorectal cancer.
Self Harm and Suicide in Adolescents
Authors: Anugrah M. Fardi , Karima Khaula , Puspita Ni Made Sri Padma , Amir Nurul Aulia Binti , Mahardika Agustine
Published: December 2023

Self harm is also called Non-Suicidal Self-Injury (NSSI). NSSI is defined as intentional self-injurious behavior to cause minor bodily harm without suicidal intent. Self-harm is strongly associated with suicidal thoughts and approximately 27-30% of adolescents with NSSI have reported suicide attempts. Based on the explanation above, the author is interested in discussing self-harm and suicide to explore the definition and management of self-harm and suicidal behavior in adolescents. In writing this literature review, we used a literature study method from various references and focused on discussions about self-harm and suicide. The search engines used were PubMed, ProQuest, and Google Scholar with the keywords "Self harm and suicide", "Epidemiology", "Diagnosis", and "Management". Overall, there were 30 articles used as references for preparing the literature review. The results of the investigation showed that self-harm and suicide are mental problems that often occur in teenagers and therefore require appropriate management using non-pharmacological and pharmacological medical approaches.
Economic Valuation of Mangrove Forest Ecosystem in Waidoba Island, South Kayoa District, South Halmahera Regency
Authors: Al Hadad M. Said , Fadel Ariyanti H. , Susanto Adi Noman , Abubakar Salim , Samman Ardan , Subur Riyadi
Published: December 2023

Mangrove Forest ecosystems have distinctive characteristics and forms and have functions and benefits as development resources both as economic resources and ecological resources that have long been felt by the Indonesian people, especially for the people who live around that area. This research aims to identify the types of utilization of mangrove forest ecosystems and to analyze the total economic value of mangrove forest ecosystems in the area of Waidoba Island, South Kayoa District, South Halmahera Regency. The sampling method in this study used a purposive sampling method. Based on the results identification of the benefits and functions of the mangrove forest ecosystem in Waidoba Island area, Kayoa Selatan District, that there were (4) four types of mangrove forest ecosystem benefits, namely (1) direct benefits (2) indirect benefits, (3) optional benefits and (4) benefits of existence. While the results of costs and benefits of the total economic value of mangrove forest ecosystem in Waidoba Island area of South Kayoa District were obtained Rp. Rp.170.520.720.104/year or Rp.418.014.659,-/ha/year. This total economic value was the benefit value of mangrove forest ecosystem that utilized by the community covering an area of 407.93 Ha.
Exploration of The Species Richness of Butterfly (Hexapoda: Odonata) in The Rice Field Ecosystem of Perian village, Montong Gading, East Lombok
Authors: Ilhamdi Mohammad Liwa , Ivansyah Aria Rizki , Syazali Muhammad
Published: December 2023

Several Odonata studies on Lombok Island still focus on forest and river habitat types. This causes the diversity of this insect group to be unknown in other habitats such as rice fields. This research aims to explore the richness of dragonfly species in the rice field ecosystem of Perian village, Montong Gading subdistrict, East Lombok district. Sample collection was carried out in May – June 2022. Dragonfly searches were carried out in the morning from 08.00 – 12.00, and in the afternoon from 14.00 – 18.00 on two transects determined purposively. The odonata found were documented using a digital camera, and captured using insect nets. Samples that were successfully collected were identified to the species taxon. The total odonata we found were 2 suborders, 5 families and 11 species. The suborder Zygoptera is the group with the highest species richness. For families, Libellulidae and Coenagrionida are the families with the highest species richness compared to other families. Of the 11 species that we found, 1 species is endemic, namely Euphaea lara lombokensis. Compared with the results of previous research conducted in Suranadi and Batu Bolong River, there are 5 species which are new records. The five species are Copera ciliata, Rhinocypha bisignata, Ischnura senegalensis, Ischnura heterosticta, and Brachythemis contaminata. The results of this study indicate that there are more species from the Odonata order on Lombok Island compared to previous reports.