bluuebunny/crossref_metadata_2025 huggingface dataset:
Les deux problèmes publics de l’affaire Robert
Authors: Aubin France , Houle Sébastien , Simard Jeanne
Published: September 2024

L’article revient sur le premier cas de divulgation à avoir été traité par le Protecteur du citoyen après l’adoption de la Loi facilitant la divulgation d’actes répréhensibles à l’égard des organismes publics (LFDAROP) : l’affaire Robert. Abordant l’affaire dans la perspective de la sociologie politique des problèmes publics, l’article montre qu’il s’agit non pas d’un, mais de deux problèmes publics : celui de l’ingérence du secteur privé dans la recherche publique et celui de la protection des lanceurs d’alerte contre les représailles. Après un retour sur les différentes solutions proposées aux deux problèmes, nous soulignons le rôle déterminant des médias avant de proposer quelques réflexions sur le projet de loi no 53 Loi édictant la Loi sur la protection contre les représailles liées à la divulgation d’actes répréhensibles et modifiant d’autres dispositions législatives, adopté récemment, en mai dernier.
Reconstructing Spatiotemporal Trajectories of Visual Object Memories in the Human Brain
Authors: Lifanov-Carr Julia , Griffiths Benjamin J. , Linde-Domingo Juan , Ferreira Catarina S. , Wilson Martin , Mayhew Stephen D. , Charest Ian , Wimber Maria
Published: September 2024

How the human brain reconstructs, step-by-step, the core elements of past experiences is still unclear. Here, we map the spatiotemporal trajectories along which visual object memories are reconstructed during associative recall. Specifically, we inquire whether retrieval reinstates feature representations in a copy-like but reversed direction with respect to the initial perceptual experience, or alternatively, this reconstruction involves format transformations and regions beyond initial perception. Participants from two cohorts studied new associations between verbs and randomly paired object images, and subsequently recalled the objects when presented with the corresponding verb cue. We first analyze multivariate fMRI patterns to map where in the brain high- and low-level object features can be decoded during perception and retrieval, showing that retrieval is dominated by conceptual features, represented in comparatively late visual and parietal areas. A separately acquired EEG dataset is then used to track the temporal evolution of the reactivated patterns using similarity-based EEG–fMRI fusion. This fusion suggests that memory reconstruction proceeds from anterior frontotemporal to posterior occipital and parietal regions, in line with a conceptual-to-perceptual gradient but only partly following the same trajectories as during perception. Specifically, a linear regression statistically confirms that the sequential activation of ventral visual stream regions is reversed between image perception and retrieval. The fusion analysis also suggests an information relay to frontoparietal areas late during retrieval. Together, the results shed light onto the temporal dynamics of memory recall and the transformations that the information undergoes between the initial experience and its later reconstruction from memory.
Existing and forthcoming obstacles in adopting technological advances in vulnerable supply chains
Authors: Raj Rohit , Kumar Vimal , Ranjana Jyoti , Anirvinna C.
Published: September 2024

The study on supply chain vulnerabilities presented in this research intends to uncover key indicators influencing the adoption of new technological advancements to enhance supply chain operations. This work used the GRA (grey relational analysis) method to conduct semi-structured interviews with the PQR company’s automotive lead design engineer, manufacturing process engineer, and optical process engineer in order to enhance the supply chain process and develop a comprehensive structural relationship to rank them to streamline the supply chain vulnerability (SCV) indicators. From the data analysis and results, cost of implementation (CI), skills gap (SG), and cultural shift (CS) are identified as the top three key indicators. However, environmental concerns (EC), regulatory compliance (RC), and supply chain complexity (SCC) have been identified as the bottom three key indicators, respectively. The study’s conclusion assists the company’s supply chain vulnerability decision-makers (DMs) in identifying critical signs impeding the uptake of new technology. As a market leader, it constantly seeks to enhance the value of its goods through supply chain management (SCM), strong management teams, and expert decision-making that will boost business performance. This study is innovative in that it uses the GRA approach to rank the important indicators of supply chain vulnerability. Managers and practitioners will benefit from this work as the organization will be able to adapt to new developments in their supply chain process and offer superior services.
Comparing the prognostic impact of 131I and/or artificial liver support system on liver function failure combined with hyperthyroidism
Authors: Fang Danzhou , Li Shiying , Zhou Changgu , Wang Yirui , Yuan Gengbiao , Zhang HuiHui , Rao Maohua
Published: September 2024

Objective

Hyperthyroidism, a prevalent endocrine disorder, can lead to complications such as liver failure due to the liver's essential role in thyroid hormone metabolism. The study aimed to elucidate the respective contributions of 131I and/or ALSS in managing hyperthyroidism alongside liver failure.

Methods

A retrospective analysis was carried out on 74 patients diagnosed with severe liver failure in the context of Graves' disease. Patients were categorized into three groups: group A (n = 34) received 131I treatment, group B (n = 17) underwent 131I and ALSS treatment, and group C (n = 24) received artificial liver support system (ALSS) treatment alone.

Results

Throughout the treatment period, the liver function indexes in all groups exhibited a declining trend. The thyroid function of group A and group B treated with 131I was significantly improved compared to that before treatment. There was no significant change in thyroid function in group C. After the correction of hyperthyroidism, significant improvements were observed in the liver function of individuals in groups A and B, particularly with more noticeable amelioration compared to group C. After two months of treatment, the efficacy rates for the three groups were 79.41%, 82.35%, and 60.87% respectively. Mortality rates of the three groups were 5.88%, 17.65%, and 36% (P < 0.01). Group B, receiving both 131I and ALSS treatments, exhibited a lower mortality rate than group C.

Conclusion

In cases of severe liver failure accompanied by hyperthyroidism, prompt administration of 131I is recommended to alleviate the adverse effects of hyperthyroidism on liver function and facilitate a conducive environment for the recovery of liver functionality.
Graves’ hyperthyroidism treated with potassium iodide: early response and after 2 years of follow-up
Authors: Fujikawa Megumi , Okamura Ken
Published: September 2024

Objective

As thionamide is associated with various adverse effects, we re-evaluated the practical efficacy of potassium iodide (KI) therapy for Graves’ hyperthyroidism (GD).

Methods

We administered KI (mainly 100 mg/day) to 324 untreated GD patients and added methimazole (MMI) only to those remaining thyrotoxic even at 200 mg/day. When the patient became hypothyroid, MMI, if taken was stopped, then levothyroxine (LT4) was added without reducing the KI dose. Radioactive iodine (RI) therapy or thyroidectomy was performed whenever required. We evaluated the early effects of KI at 2–4 weeks and followed patients for 2 years.

Results

At 2 weeks, serum thyroid hormone levels decreased in all 324 patients. At 4 weeks, fT4, fT3, and both fT4 and fT3 levels became normal or low in 74.7%, 50.6%, and 50.6% of patients, respectively. In a cross-sectional survey over 2 years, GD was well-controlled with KI or KI + LT4 (KI-effective) in >50% of patients at all time points. Among 288 patients followed for 2 years, 42.7% remained ‘KI-effective’ throughout the 2 years (KI Group), 30.9% were well-controlled with additional MMI given for 1–24 months, and 26.4% were successfully treated with ablative therapy (mainly RI). Among ‘KI-effective’ patients at 4 weeks, 76.5% were classified into the KI Group. No patients experienced adverse effects from KI.

Conclusion

KI therapy was useful in the treatment of GD. A sufficient dose of KI was effective in >50% of GD patients from 4 weeks to 2 years, and 42.7% (76.5% of ‘KI-effective’ patients at 4 weeks) remained ‘KI-effective’ throughout the 2 years.
ОСОБЛИВОСТІ ФОРМУВАННЯ ПЕДАГОГІЧНОЇ КОМПЕТЕНТНОСТІ МАЙБУТНІХ УЧИТЕЛІВ У ЄВРОПІ ТА СВІТІ
Authors: СЕМБРАТ АЛЛА
Published: September 2024

У статті окреслено проблему формування педагогічної компетентності майбутніх учителів з позиції сьогодення. Наголошується, що даний процес має бути неперервним, спрямованим на вироблення новітньої стратегії, яка орієнтована на затребуваність на ринку праці конкурентоздатних педагогів. Автором проведений порівняльний аналіз на прикладі України, окремих європейських і держав світу системи формування фаховості майбутніх педагогів у закладах вищої освіти. Дано характеристику сучасного світового і вітчизняного досвіду професійного розвитку студентів ‒ майбутніх спеціалістів у процесі здобуття ними освіти у закладах вищої освіти.
Modeling of Two-component Mixtures of Shifted Distributions with Zero Cumulant Coefficients
Authors: Krasilnikov A.I.
Published: September 2024

For two-component mixtures of shifted distributions a general formula for finding the value of the shift parameter , at which the cumulant coefficients of any order are equal to zero, is obtained. An algorithm for mathematical and computer modeling of two-component mixtures of shifted distributions with zero cumulant coefficients is formulated. General formulas for two-component mixtures of shifted gamma-distributions with zero cumu-lant coefficients of any order are obtained and examples of mixtures with zero skewness and kurtosis coefficients are given. General formulas of two-component mixtures of shifted Stu-dent’s distributions with zero cumulant coefficients of any order are obtained and examples of mixtures with zero kurtosis coefficient and coefficient are given. The research results provide the practical possibility of using two-component mixtures of shifted distributions for mathematical and computer modeling of non-Gaussian random variables with zero cumulant coefficients of any order.
Improvement of Protective Effects on Dangerous High-Frequency Impression Signals
Authors:   G.E. Pukhov Institute for Modelling in Energy Engineering  National Academy of Sciences of Ukraine, Kyiv, Zaika N. , Rakovych V. ,   G.E. Pukhov Institute for Modelling in Energy Engineering  National Academy of Sciences of Ukraine, Kyiv, Komarov M. ,   G.E. Pukhov Institute for Modelling in Energy Engineering  National Academy of Sciences of Ukraine, Kyiv, Laureyssens E. ,   State Research Institute of Cyber Security Technologies, Kyiv
Published: September 2024

The paper examines the issue of risk management in critical infrastructure facilities, highlight-ing the analysis of existing approaches and methods used to assess negative threats. Particular attention is paid to the importance of using information technologies for data collection and processing, as well as to the complexity of developing a systematic risk management method-ology. Tracking activity in social networks, analyzing browser history and other data allows you to analyze and track a person’s psychological and physical state. Having access to infor-mation about interests and personal issues gives attackers the opportunity to develop various types of influence, including pressure, blackmail and manipulation.
Review of Steganographic Methods and their Application in Securing Banking Information Systems
Authors:   National Technical University  ", Umanskiy O.G. ,   Kharkiv Polytechnic Institute"
Published: September 2024

The article provides a detailed analysis of modern steganographic methods and their practical applications across various fields, with a focus on the prospects for integration into banking systems. It examines key steganographic methods, including Least Significant Bit (LSB) sub-stitution, Discrete Cosine Transform (DCT), and Discrete Wavelet Transform (DWT), as well as hybrid approaches combining steganography with cryptography. The impact of stega-nographic methods on enhancing the security of internal communications, protecting client da-ta, and ensuring the continuity of business processes in the banking sector is analyzed. The ar-ticle presents real-world examples of implementing steganography to protect online tran¬sac-tions and mobile banking, and discusses the main stages of integrating these methods into banking systems, including security requirement analysis, testing, and staff training.
Evolution of Treatment Modalities for Disseminated HAdV Infection in Neonates
Authors: Zhang Wenjing , Liu Fang , Liang Enlin , Zhang Li
Published: September 2024

Human adenovirus (HAdV) infection in newborns is a rare condition that typically affects multiple organ systems and has a high mortality rate. We report a case of neonatal HAdV-D37 infection that presented with fever and respiratory distress that was confirmed by metagenomic next-generation sequencing using blood and bronchoalveolar lavage fluid. We treated the patient with intravenous immunoglobulin, methylprednisolone, and anticoagulants, and the patient recovered. Our review of 41 cases of HAdV found that treatment with intravenous immunoglobin might have improved the outcome of HAdV-D infection. We further suggest that glucocorticoid therapy may have additional therapeutic validity in the setting of severe or disseminated disease and that monitoring coagulation function and timely anticoagulation treatment should be considered to prevent complications associated with disseminated intravascular coagulation.
The need for practicality and applicability: A longitudinal study involving pre-service English teachers
Authors: Simon Krisztián
Published: September 2024

A key issue that teacher training programmes need to address is how well the contents of various methodology courses translate to in-class uses for pre-service teachers to use during their teaching practices. The paper addresses the problem from multiple angles in a longitudinal project that collected quantitative and qualitative data regarding fourth-year Hungarian pre-service English teachers' views about the practicality and applicability of various EFL methodology course contents. The study found that the key needs pre-service teachers have in connection to the applicability of their course contents corresponds to their developing identities as future teachers. Conclusions are drawn regarding a possible support model utilizing semi-open ended teaching material support and the application possibilities of blended learning.
ISLAMIC EDUCATIONAL APPROACHES TO STUNTING PREVENTION AND CHILD PROTECTION
Authors: Samad Sri Astuti A. , Samad Munawwarah , Ramli Saiful , HR Sabriadi , Ilyas Ilyas
Published: September 2024

Stunting, characterized by impaired growth and development in children under five years old, represents a significant global nutritional issue, particularly in Indonesia. This study aims to explore stunting prevention and child protection from the perspective of Islamic education. Employing a qualitative methodology with a phenomenological approach, the research seeks to understand and interpret specific events and social situations related to stunting and child protection within the Indonesian context. Data were collected through in-depth interviews and documentation, specifically involving lecturers at UIN Ar-Raniry Banda Aceh. The findings reveal that the incidence of stunting in Indonesia remains alarmingly high compared to other middle-income countries, leading to decreased cognitive abilities, heightened health risks, and diminished future productivity. The research concludes that stunting prevention and child protection are critical national programs that require synergistic implementation to secure a better future for children and ensure their right to quality education. From the perspective of Islamic education, these efforts are intrinsically linked, as Islamic teachings emphasize the importance of proper care, provision of halal and nutritious food, which positively influence both the physical and mental well-being of children. The study highlights the need for integrating Islamic educational principles in national stunting prevention strategies to foster holistic child development.
Uniting Through Humour: Navigating Interreligious Dialogue in Indonesia's Cyberspace During Elections
Authors: Saifatunnisa Yuri Nabila , Almubarokah Ulfah Wafa , Arighi Raihan Aqhsal , Abidin Muhammad Salman
Published: September 2024

Purpose: This study explores the role of humour in fostering interreligious dialogue and cooperation within Indonesia’s digital spaces, particularly during the politically charged atmosphere of the 2024 general election. Methodology: Employing netnography, this research focuses on the 'Garis Lucu' (GL) cyberculture, analysing interactions on platforms like Twitter and Instagram to understand how humour mediates religious and political discourse. Findings: The study identifies three main themes: political engagement, political communication, and religious humour. Humour was found to significantly enhance civic engagement and function as a bridge in interreligious communication, easing tensions and fostering a culture of mutual respect and understanding. Research Implications: The findings suggest that digital platforms can serve as effective forums for promoting societal harmony and tolerance through humour, particularly in diverse societies facing political and religious tensions. Originality/Value: This research contributes to the understanding of cyberculture and interreligious dialogue by illustrating how humour can transform potentially divisive political interactions into opportunities for constructive and harmonious exchanges.
ReproduceMe: Lessons from a pilot project on computational reproducibility
Authors: Baker Daniel H. , Berg Mareike , Hansford Kirralise J. , Quinn Bartholomew P.A. , Segala Federico G. , Warden-English Erin L.
Published: September 2024

If a scientific paper is computationally reproducible, the analyses it reports can be repeated independently by others. At the present time most papers are not reproducible. However, the tools to enable computational reproducibility are now widely available, using free and open source software. We conducted a pilot study in which we offered ‘reproducibility as a service’ within a UK psychology department for a period of 6 months. Our rationale was that most researchers lack either the time or expertise to make their own work reproducible, but might be willing to allow this to be done by an independent team. Ten papers were converted into reproducible format using R markdown, such that all analyses were conducted by a single script that could download raw data from online platforms as required, generate figures, and produce a pdf of the final manuscript. For some studies this involved reproducing analyses originally conducted using commercial software. The project was an overall success, with strong support from the contributing authors who saw clear benefit from this work, including greater transparency and openness, and ease of use for the reader. Here we describe our framework for reproducibility, summarise the specific lessons learned during the project, and discuss the future of computational reproducibility. Our view is that computationally reproducible manuscripts embody many of the core principles of open science, and should become the default format for scientific communication.
Rola (post)pamięci i filmu w południowokoreańskiej narracji narodowej oraz jej wpływ na relacje z Japonią
Authors:   Ośrodek Spraw Azjatyckich, Uniwersytet Łódzki, Beczkowska Joanna
Published: September 2024

There seems to be a barrier in relations between Japan and South Korea that, despite shared interests and values, is an obstacle to building a lasting reconciliation. Political solutions that are supposed to be permanent and unchangeable (such as the agreement on comfort women) are being undermined. The idea of unresolved historical disputes and the lack of sufficient apologies has been ingrained in South Korea, which influences the perception of Japan as a dishonest partner. Subsequently, the brutality of authoritarian rule and the restriction of civil rights became associated with the legacy of the colonial period. Although political elites on both sides agree on the need to build future- oriented relationships, these efforts encounter internal resistance. Analysis of the role played by the collective memory of the colonial period allows us to notice antagonisms that lead to the reification of reality in which lasting reconciliation without solving historical disputes is impossible. Using the film, a post-memory with a strongly emotional tone is constructed, reinforcing anti-Japanese resentments. The analysis of the development of film narratives about the colonial period serves to capture changes in the national discourse and leads to conclusions regarding the impact not only on relations with Japan, but also on the connection between the anti-colonial discourse and the criticism of authoritarian power. The rhetorical vision presented in the films has been so deeply rooted in the national narrative that changing it seems extremely difficult - which is why it constantly threatens the building of lasting reconciliation with Japan.
Polskie portale informacyjne wobec dokumentu Franciszkańska 3 Marcina Gutowskiego – analiza zawartości z perspektywy personalistycznej
Authors:   Uniwersytet Dolnośląski DSW we Wrocławiu, Węglińska Agnieszka , Harbanowicz Justyna ,   Uniwersytet Dolnośląski DSW we Wrocławiu
Published: September 2024

The subject of the analysis was the person of Karol Wojtyła, presented in the five most opinion-making news portals in the context of the documentary Franciszkańska 3 in the first eight days after its broadcast on TVN24. The adopted research perspective is the phenomenon of personalization. The paper aims to analyse how the five leading news portals presented the person of Karol Wojtyła in the context of the documentary Franciszkańska 3. In the research, both quantitative and qualitative, the authors verify the hypothesis that in the documentary and the analysed texts, the reactions to the crime of paedophilia among the clergy in the diocese of Krakow are interpreted in the context of Karol Wojtyła’s personal responsibility and not of the institution. The research results confirm the above hypothesis.
Inicjatywa Środkowoeuropejska w okresie bułgarskiej prezydencji sprawowanej w 2022 roku
Authors:   Polska Akademia Nauk, Czernicka Marzena
Published: September 2024

This text analyses the implementation of the main priorities of the Bulgarian Presidency of the Central European Initiative (CEI) in 2022. The current activities of the Initiative are presented through an analysis of priorities and planned tasks. This analysis shows that the CEI – which recently celebrated its 30th anniversary – is meticulously performing the tasks for which it was established. It undertakes a number of activities for the integration within the EU, regional security and sustainable development issues. Almost all the planned events were organized during the Bulgarian Presidency. Meetings were held in each of the areas of the CEI activity, i.e. the parliamentary, governmental, economic and recently developed local dimensions. The official programme of the Presidency, the indicative calendar of events, as well as information published on the official website of the Initiative and on the websites of some Bulgarian ministries and institutions involved in the Presidency, form the basis of the research.
“Sr. Critico” José Veríssimo (1857-1916): a metonímia e a fortuna crítica (1916-1974)
Authors: Moraes Felipe Tavares de
Published: September 2024

RESUMO Realiza-se neste trabalho a análise do lugar assumido pela obra de José Veríssimo no pensamento brasileiro enquanto representante da crítica e história literária produzida no final do século XIX e início do XX, por meio de diferentes leituras sobre sua vida, obra e personalidade. Por contraste, são abordadas as apreciações realizadas por essas leituras a respeito da sua atuação educacional e estudos sobre Amazônia. Com uma abordagem teórica da história e crítica literária, o artigo examina a trajetória da fortuna crítica que escrutinou a produção intelectual de José Veríssimo no transcorrer do século XX, dos folhetins de jornais à tese universitária. Desse conjunto de leituras emergiu, de uma trajetória intelectual marcada pela diversidade de temáticas, enciclopédica em abordagens e erudita em conhecimentos, a imagem do “Sr. Critico”: uma metonímia que destacou o crítico/historiador literário em detrimento do polígrafo intelectual oitocentista.
Geographical context and HIV/AIDS: multiple health perspectives on Mozambican women
Authors: Pedroso Mateus Fachin , Guimarães Raul Borges , Cau Boaventura Manuel
Published: September 2024

Abstract The aim of this article is to understand the gender vulnerability experienced by women living with HIV/Acquired Immunodeficiency Syndrome (AIDS) in the city of Maputo, Mozambique, according to the reports of representatives and leaders of the health services who work directly on the issues of these conditions for the female public. To this end, the research was based on qualitative methodologies, since the production of the data was supported by a semi-structured script that considers the following themes: HIV/AIDS; gender; culture; and health services. The interpretations are mediated by Discourse Analysis (DA), which enables immersion in linguistic resources through meanings and connections. This allows us to interpret the complexity of the geographical context of women living with HIV/AIDS in the region, highlighting the need to promote actions toward the issues surrounding the disease, since it is urgent to establish a geographical interpretation of health, especially considering the reality lived by women who experience difficulties, oppression, stigma, and discrimination on a daily basis.
Radikal Prostatektomi Sonrası Erken Dönem Komplikasyonları Etkileyen Faktörlerin Değerlendirilmesi
Authors: Arıkan Ozgur , Keser Ferhat , İplikçi Ayberk , Keleş Ahmet , Efiloğlu Özgür , Yıldırım Asıf
Published: September 2024

Amaç: Radikal prostatektomi (RP) sonrası komplikasyonları ve erken dönemde hastaneye tekrar başvuruları azaltmak öngörücü faktörlerin belirlenmesiyle sağlanabilir. Bu çalışmanın amacı RP uygulanan hastalarda, hastanede kalış süresinde uzama ve postoperatif erken dönemde hastaneye tekrar başvuruları öngörmede etkili parametreleri araştırmaktır. İkinci amaç ise bu hastalardan yaşlı grupta (65 yaş ve üzeri) postoperatif komplikasyon gelişiminde etkili parametreleri belirlemektir.
Materyal ve Metod: Retrospektif olarak yapılan çalışmada Şubat 2022 ile Şubat 2023 arasında prostat kanseri tanısı ile kliniğimizde açık retropubik RP uygulanan hastaların verileri değerlendirildi. Komorbidite durumları Charlson Komorbidite İndeksi (CCİ) ile; malnütrisyon durumları ise mini nütrisyonel değerlendirme (MNA) testi ile değerlendirildi.
Bulgular: Toplam 27 hastada (%27) postoperatif erken dönemde komplikasyon gelişti. MNA testine göre hiçbir hasta malnütrisyonlu değildi. Hastaların büyük çoğunluğunun (%91) beslenmesi normaldi. Postoperatif erken dönemde komplikasyon gelişen hastalar ile gelişmeyen hastalar karşılaştırıldığında (grup 1 vs. grup 2), sigara kullanımı, kilo, VKİ, hemoglobin, eGFR, ALT, AST ve albumin değerleri arasında fark izlenmedi. İki grup arasında MNA testi karşılaştırıldığında, komplikasyon gelişenlerde ortalama malnütrisyon skoru daha düşüktü ve bu istatistiksel olarak anlamlı bulundu (grup 1:25,5 vs. grup 2:26,4, p=0,019). Komplikasyon gelişenler; yatış süresi uzayanlar (grup P) ve taburculuk sonrası erken dönemde tekrar hastaneye başvuranlar (grup R) olarak iki gruba ayrıldığında, 17 (%17) hastanın yatış süresinin uzadığı, 10 (%10) hastanın postoperatif erken dönemde tekrar başvuruda bulunduğu görüldü. İki grup karşılaştırılarak alt grup analizi yapıldığında ortalama MNA skoru (grup P:26,2±2,0 vs. grup R:24,3±1,0, p=0,005) R grubunda istatistiksel anlamlı olarak daha düşüktü. Uzamış yatış süresi için risk faktörlerine bakıldığında, çok değişkenli regresyon analizinde CCİ (p=0,006) bağımsız risk faktörü olarak belirlendi. Hastaneye tekrar başvuru için risk faktörlerine bakıldığında, çok değişkenli regresyon analizinde malnütrisyon riski (p=0,035) bağımsız risk faktörü olarak belirlendi.
Sonuç: Lokal evre prostat kanseri tanısıyla RP uygulanan hastalarda; MNA skoru, yaş ve boy ölçüsü, postoperatif erken dönemde komplikasyon gelişimi için birer prediktör olabilir. Yaşlı hastalarda ise; malnütrisyon riski ve komorbidite sayısı, postoperatif komplikasyonları öngörmek için değerli görülmüştür.
OKUL ÇAĞI DÖNEMİNDE VEYA SONRASINDA SÜNNET OLMA: RETROSPEKTİF DEĞERLENDİRME
Authors: Ulusoy Tangül Sevgi , Şenaylı Atilla
Published: September 2024

Amaç: Hastanemizin bulunduğu bölgede sünnet çoğunlukla okul öncesinde yani 6 yaş ve öncesinde yapılmaktadır. Okul öncesi dönemini tercih edilmesindeki etken faktörün ise ailelerin okul başlamadan bu süreci tamamlamak istemeleri olduğu anlaşılmaktadır. Bir kısım çocukların ise genel tercihin aksine altı yaş veya üstünde sünnet oldukları tespit edilmiştir. Çalışmamızda altı yaş üstü sünnet edilen hastaların tercih nedenlerinin araştırılması ve işlem sürecinin değerlendirilmesi amaçlanarak bu tercihteki faktörlerin tespit edilmesi planlanmıştır.
Metot: Hastanemizde 2018-2023 yılları arasında sünnet işlemi yapılmış çocukların elektronik ortamda arşivlerine ulaşıldı. Bu çocuklardan 6 yaş ve üzerinde olanların dosyaları incelendi. Bu gruptaki hastaların işlem sonrası poliklinik kontrolüne gelenler çalışmaya alındı. Bu sayede sünnet işlemi sonrasında okul çağı ve üstünde yaş grubunda olup işlem sonrası kontrole gelenlerin genel değerlendirilmesi yapıldı. Elde edilen sonuçlar literatürle kıyaslanarak değerlendirildi.
Bulgular: Sünnet işlemi yapılan 1145 çocuk tespit edildi. Çocukların 91’inin 6 yaş ve üzerinde olduğu ve bu hastalardan 53’ünün sünnet sonrasındaki kontrollere geldiği anlaşıldı. Bu çocukların okul yaşı ve üstü grupta sünnet ettirilme sebepleri çok faktörlü olarak görüldü. İleri okul dönemi yaşı, beraberinde herni, inmemiş testis, enürezis, Henoch-Schönlein Sendromu gibi hastalıkların varlığı, yurtdışında yaşıyor olmak gibi durumlar tespit edildi. Ortalama 1,3 gün yatış yapıldı. Hiçbirinde komplikasyon olmadı ve kontrol muayeneleri hepsinde normaldi.
Sonuç: Genelde sünnet işlemi okul öncesinde istenmesine karşı dış etkenler ve ailevi etkenler de işlemin ertelenme gerekçesidir. Ancak bu grup genel toplama göre azınlıktadır. İşlemin etkisi açısından sürecin bu yaşlarda yürütülmesinin ek sorunlara sebep olmadığı görülmüştür. Bölgemizdeki yaş dağılımı geneline bakıldığında ülkemizde yapılan bazı çalışmalarda 8 yaş ve üzeri sünnet yapıldığı için sonuçlarımızın oldukça farklı olduğu anlaşıldı.
Правовое регулирование обязательств из публичного конкурса в государствах-участниках СНГ
Authors: Гусева Татьяна , Казакова Марина , Низамова Елена
Published: September 2024

Статья посвящена исследованию правового регулирования обязательств из публичного конкурса в государствах-участниках СНГ и оценке его соответствия современным потребностям социально-экономического, культурного и духовного развития стран Содружества. Целью сравнительного анализа и оценки национального законодательства и правоприменения стран СНГ является выработка единого подхода к правовому регулированию обязательств из публичного конкурса. Это будет способствовать международному сотрудничеству и обмену передовым опытом решения значимых социально-экономических и инновационных задач. Анализ доктринальных источников, национального законодательства и правоприменительной практики о публичном конкурсе в государствах-участниках СНГ позволил раскрыть динамику обязательства из публичного конкурса, установить правовой статус сторон обязательства, определить оптимальные способы защиты их прав и законных интересов. Авторами установлено, что положения ряда национальных законодательств стран Содружества о публичном конкурсе, крайне лаконичные, а в некоторых случаях и противоречащие принципам гражданского права, создают почву для злоупотреблений организатора конкурса и не обеспечивают защиты прав его участников. Показано как пробелы и противоречия в регулировании препятствуют действенности публичного конкурса. В результате исследования предложена модель правового регулирования обязательства из публичного конкурса, охватывающая все его этапы, и включающая наряду с имеющимся арсеналом положения, регулирующие аспекты обязательств из публичного конкурса, значимые, но остающиеся вне правового поля. Выработанные авторами подходы к правовому регулированию обязательств из публичного конкурса, с одной стороны, могут служить основой гармонизации национального законодательства стран-участниц СНГ и таким образом способствовать его сближению и созданию единого правового пространства на территории Содружества. C другой стороны, новые подходы способны обеспечивать соблюдение принципов конкурсного обязательства: состязательности и прозрачности публичного конкурса, независимости и объективности оценки работ участников, защиты их прав и законных интересов. Налаженный механизм правового регулирования способен содействовать результативности публичного конкурса и расширению его применения в разнообразных сферах жизнедеятельности.
Способы волеизъявления сторон в условиях цифровой трансформации: актуальные тренды правоприменения
Authors: Фролова Евгения , Берман Алиса
Published: September 2024

Авторы рассматривают современные способы волеизъявления сторон в условиях цифровой трансформации и их влияние на практику правоприменения. Особое внимание уделяется таким аспектам, как цифровизация, смарт-контракты, clickwrap, browse-wrap и shrink-wrap соглашения, а также использование биометрической идентификации для совершения сделок. Также подвергается анализу новый тренд — использование эмодзи как замены подписи на договоре. Исследована зарубежная и отечественная судебная практика, свидетельствующая о придании эмодзи юридического значения. Отдельное внимание уделено вопросам кибербезопасности в контексте цифровых сделок. Предложено авторское видение понимания смарт-контрактов, сlick-wrap соглашения, browse-wrap соглашения, shrink-wrap соглашения. Анализируются преимущества и риски использования данных инструментов, а также предлагаются рекомендации к обеспечению правовой действительности, безопасности и эффективности таких цифровых сделок. Прослеживается тенденция кратного роста новых цифровых явлений, заслуживающих правового регулирования, идущих в ногу со стремительным проникновением в сферу имущественных правоотношений технологий, революционизирующих ее принципиально новыми возможностями предпринимательской деятельности. Ими создан диапазон новых категорий, в той или иной мере становящихся объектами правового регулирования или заслуживающими того, чтобы стать ими — «большие данные», «блокчейны», «цифровые активы», «цифровые права» и др. Цифровая трансформация, интегрируясь в предпринимательскую деятельность, качественно изменяет ее. Зачастую весь процесс от момента заключения сделки до ее завершения совершается в электронном виде. Для успеха экономического сотрудничества необходимо создание быстрых и гибких способов разрешения споров. Достигнуть данных целей возможно за счет интегрирования в данный процесс современных информационно-телекоммуникационных технологий. Общей тенденцией в процессе разрешения споров является переход к электронной форме. Анализируется отечественная и зарубежная литература, посвященная выявлению роли и значения права в регулировании отношений, связанных с цифровизацией, и делается вывод, что правовая наука приступила к масштабному и глубокому исследованию содержания и методов регулирования отношений по поводу искусственного интеллекта.
Isolation of Nuclei from Brain Tissue Using Gradient Centrifugation for Myelin Depletion for 10x Genomics Platform v1
Authors: Institute Allen
Published: September 2024

Protocol is used for isolation of nuclei from frozen brain tissue orthawed and microdissected brain tissue sections for RNA-seq analysis. Note: Research reported in this publication was supported by the National Institute Of Mental Health of the National Institutes of Health under Award Number UM1MH130981. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health
Quantum Computing Impact on Traditional Computer Architecture Models
Authors:   Alnoor University, Attya Salih Mahmoud , Haddad Suhad Qasim G. ,   Al Mansour University College, Al-Zaidi Hamid Kareem Radam ,   Al Hikma University College, Hameed Wafaa Mustafa ,   Cihan University Sulaimaniya, Latif Nabaa ,   Al-Turath University
Published: September 2024

Background: Traditional computer architectures are based on classical computational techniques, challenged by rapid advances in quantum computing. Quantum computers use quantum bits (qubits) to do calculations at speeds unreachable by classical computers, possibly revolutionizing many fields by providing exponential improvements in processing power. Objective: The article aims to investigate the potential consequences of quantum computing on traditional computer architectural models, emphasizing integration issues and transformative powers. Methods: We conducted extensive literature reviews and simulations to compare the performance of quantum and classical computing architectures in various computational workloads. Key performance metrics were developed to evaluate the scalability, efficiency, and feasibility of incorporating quantum computing principles into existing architectural models. Results: The findings indicate that quantum computing has the potential to improve significantly processing speeds and efficiency for specific algorithmic procedures, particularly cryptography and large-scale data analysis. However, modern quantum computers have hurdles in terms of error rates and qubit coherence times, complicating their integration with standard architectures. Conclusion: While quantum computing represents a paradigm change with promising improvements in computational speed and efficiency, significant technological advances are needed before it can be fully integrated into existing computer architecture models. Continued research and development are required to overcome these hurdles and realize quantum computing's full promise in improving traditional computing systems.
Treatment of children with forearm deformities using the Ortho-SUV navigation system
Authors: Ryzhikov Dmitry V. , Belousova Ekaterina A. , Pozdeev Alexander P. , Vissarionov Sergey V.
Published: September 2024

Background. Children with congenital dysplastic skeletal disorders often develop various multi-axial bone deformities in the forearm during growth, most commonly occurring against the backdrop of polyosseous exostotic chondrodysplasia. The main surgical treatment method for these children is currently external fixation. To correct pronounced angular deformities of the forearm bones, the use of a passive computer navigation system can be advantageous.
The aim of the study is to compare the outcomes of correcting multi-axial deformities of the forearm bones in children using the Ortho-SUV navigation system versus without its use.
Methods. The study is based on the analysis of examination and treatment results of 36 patients aged 4 to 16 years with forearm deformities associated with exostotic chondrodysplasia. All patients were examined and treated between 2008 and 2022 and were divided into two groups: the main group and the control group. The main group consisted of 13 patients who underwent the correction of forearm bone angular deformities using the Ortho-SUV navigation system based on passive computer navigation. The control group included 23 patients who had their forearm bone deformities corrected in the operating room by reducing bone fragments with an external fixator without the use of the Ortho-SUV navigation system.
Results. Comparative assessment of the anatomical and functional outcomes in the studied groups showed that good results were achieved in 52.7% of cases (n = 19), most of them in the main group (n = 13). Satisfactory results were obtained only in the control group, where 17 (47.2%) patients experienced satisfactory outcomes.
Conclusion. The use of the Ortho-SUV navigation system for correcting multi-axial deformities of the forearm bones in children allows for highly precise, dosed correction of all components of the deformities, achieving good radiological and functional outcomes.
Digitalization in forensic medicine
Authors: Ardashkin Anatolii P. , Sergeev Vladimir V.
Published: September 2024

BACKGROUND: A decree of the President of Russia defines the introduction of digital technologies as a national goal for the breakthrough development of the country. The development of digital technologies in forensic medicine ensures the success of individual expert tasks and demonstrates the possibility of digital transformation in forensic activity.
AIM: To examine the attitude of forensic experts toward digital transformation in their professional activity.
MATERIALS AND METHODS: A survey was developed for 77 forensic experts from the Bureau of Forensic Examination of the Republic of Bashkortostan and Voronezh, Kirov, and Samara regions. A questionnaire survey containing six questions with three answer options each was developed in accordance with the purpose and objectives of the study.
The methods of variation statistics, analysis, synthesis, and comparison were used.
RESULTS: This study investigated the level of experts’ understanding of the goals of digital transformation in medicine, assessed the experts’ perception of the process of digital transformation in forensic medicine, analyzed the experts’ awareness of the application of digital technologies in expert practice, determined the attitude of experts toward the digital transformation in forensic medicine, and evaluated the respondents’ opinion on the possible impact of digital technologies on the objectivity of the results of expert studies. The viewpoints of forensic practitioners on the relevance and importance of digital transformation in forensic activity were obtained. The recommendations for optimization of digital transformation in forensic medical activity were generated.
CONCLUSION: Forensic experts show a low level of interest on the issue of digital transformation in forensic activity. In the present case, experts have highlighted the relevance of digital transformation for their professional activity and cognitive importance of digital technologies for expert knowledge.
Historia clínica del edéntulo total
Authors:   Universidad César Vallejo, Terrones Campos Wilfredo , Pairazamán García Juan ,   Universidad Privada Antenor Orrego
Published: September 2024

1. Acuérdate de tu Creador en los días de tu juventud, antes que vengan los días malos, y lleguen los años de los cuales digas: No tengo en ellos contentamiento; 2. antes que se oscurezca el sol, y la luz, y la luna y las estrellas, y vuelvan las nubes tras la lluvia; 3. cuando temblarán los guardas de la casa, y se encorvarán los hombres fuertes, y cesarán las muelas porque han disminuido, y se oscurecerán los que miran por las ventanas; … Santa Biblia. Eclesiastés. Capítulo 12, versículo 1-3. Texto bíblico Reyna Valera, 1960. La historia clínica del edéntulo total es un documento médico odontológico con un valor clínico y legal. Es producto de la interacción del estomatólogo con el paciente donde se recoge la información necesaria de forma ordenada, secuencial y precisa. Su finalidad es llegar a un diagnóstico, pronóstico y un plan de tratamiento adecuado y oportuno por parte del especialista. Lamentablemente, muchos profesionales dejan de lado la elaboración de la historia clínica por el tiempo que demanda realizarla; sin embargo, es necesaria para garantizar un buen tratamiento y cumplir con las expectativas del paciente. Se necesita de mucha audacia y capacidad por parte del especialista para poder obtener la información necesaria que ayude a identificar la enfermedad. Por eso, el estomatólogo se basa de medios de diagnóstico como la palpación, percusión, inspección y auscultación para la elaboración de la historia clínica.
KİŞİLERARASI ÖFKE VE DİNDARLIK İLİŞKİSİ: ŞOFÖRLER ÜZERİNE NİCEL BİR ARAŞTIRMA
Authors: Duran Mehmet Emrullah
Published: September 2024

Bu araştırmada, şoförlerin kişilerarası öfke ve dindarlık düzeyleri arasındaki ilişki incelenmiştir. 2024’ün Şubat ayında gerçekleştirilen araştırmaya Konya’da çalışmakta olan 265 şoför katılmıştır. Araştırmanın amacı kapsamında ilişkisel tarama modeli kullanılmıştır. Araştırma verileri anket tekniğiyle toplanmış ve anket formunda Kişisel Bilgi Formu, Kişilerarası Öfke Ölçeği ve Dini Tutum Ölçeği kullanılmıştır. Veri analizinde Perason Korelasyon Analizi ve T Testi kullanılmıştır. Araştırma sonucunda kişilerarası öfke ile dindarlık arasındaki ilişkinin negatif yönde güçlü düzeyde ve istatistiksel olarak anlamlı olduğu, dindarlık puanları yükseldikçe kişilerarası öfkenin azaldığı tespit edilmiştir. Kişilerarası öfkenin alt boyutları olan intikam tepkileri, pasif agresif tepkiler, içe dönük tepkiler ve umursamaz tepkiler ile dindarlığın alt boyutları biliş, duygu, davranış ve ilişki arasındaki ilişkinin negatif yönde güçlü düzeyde ve istatistiksel olarak anlamlı olduğu saptanmıştır. Şoförlerin kişilerarası öfke ve dindarlık puanlarının yaş değişkenine göre istatistiksel olarak anlamlı farklılık gösterdiği bulgusuna ulaşılmıştır. Ayrıca kişilerarası öfke puanının aracın niteliği değişkenine göre istatistiksel olarak anlamlı farklılık gösterdiği tespit edilmiştir.
A REVIEW ON MOTHER GODDESS PARADOX IN LYDIAN SYNCRETISM
Authors: Külahlı Nuriye
Published: September 2024

The cultural mosaic of the Lydian civilization manifests itself most intensely in its religious structure. Many gods and goddesses attract attention in Lydian syncretism. While goddesses stand out with their different characteristics, the problem of the mother goddess has long been a subject of curiosity for today's researchers. This situation has the nature of a paradox as there is no consensus on this situation with different opinions. Lydian goddesses of Anatolian and Greek origin stood out with their different characteristics and spheres of influence. However, which one is the mother goddess remains a mystery. Artemis, Demeter, Kore, Kybele and Athena are the goddesses most frequently mentioned in ancient sources and most frequently depicted in visual finds. In this case, the Greek goddesses, who are numerous in number, and the famous Anatolian goddess Kybele, whose sphere of influence is quite wide and in a powerful position, face each other in the same pantheon. In this study, an evaluation was made by considering the influence areas of Lydian goddesses and their frequency of reflection in existing epigraphic and numismatic finds. In this evaluation of the mother goddess paradox in Lydian syncretism, ancient artifacts, Sardis inscriptions and coins were mainly examined.