bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamics of spin-momentum entanglement from superradiant phase transitions
Authors: Chelpanova Oksana , Seetharam Kushal , Rosa-Medina Rodrigo , Reiter Nicola , Finger Fabian , Donner Tobias , Marino Jamir
Published: August 2024

Exploring operational regimes of many-body cavity QED with multilevel atoms remains an exciting research frontier for their enhanced storage capabilities of intralevel quantum correlations. In this work, we consider an experimentally feasible many-body cavity QED model describing a four-level system, where each of those levels is formed from a combination of different spin and momentum states of ultracold atoms in a cavity. The resulting model comprises a pair of Dicke Hamiltonians constructed from pseudospin operators, effectively capturing two intertwined superradiant phase transitions. The phase diagram reveals regions featuring weak and strong entangled states of spin and momentum atomic degrees of freedom. These states exhibit different dynamical responses, ranging from slow to fast relaxation, with the added option of persistent entanglement temporal oscillations. We discuss the role of cavity losses in steering the system's dynamics into such entangled states and propose a readout scheme that leverages different light polarizations within the cavity. Our work paves the way to connect the rich variety of non-equilibrium phase transitions that occur in many-body cavity QED to the buildup of quantum correlations in systems with multilevel atom descriptions.

Published by the American Physical Society
2024
Flip-Chip-Based Fast Inductive Parity Readout of a Planar Superconducting Island
Authors: Hinderling M. , Kate S.C. ten , Haxell D.Z. , Coraiola M. , Paredes S. , Cheah E. , Krizek F. , Schott R. , Wegscheider W. , Sabonis D. , Nichele F.
Published: August 2024

The properties of superconducting devices depend sensitively on the parity (even or odd) of the quasiparticles that they contain. Encoding quantum information in the parity degree of freedom is central in several emerging solid-state qubit architectures, including in hybrid superconductor-semiconductor devices. In the latter case, accurate, nondestructive, and time-resolved parity measurements are a challenging issue. Here, we report on control and real-time parity measurement in a superconducting island embedded in a superconducting loop and realized in a hybrid two-dimensional heterostructure using a microwave resonator. To avoid microwave losses impeding time-resolved measurements, the device and readout resonator are located on separate chips, connected via flip-chip bonding, and couple inductively through vacuum. The superconducting resonator detects the parity-dependent circuit inductance, allowing for fast parity readout. We have resolved even- and odd-parity states with a signal-to-noise ratio of SNR≈3 for an integration time of 20μs and a detection fidelity exceeding 98%. The real-time parity measurement shows a state lifetime extending into the millisecond range. Our approach will lead to a better understanding of coherence-limiting mechanisms in superconducting quantum hardware and help to advance inductive-readout schemes for hybrid qubits.

Published by the American Physical Society
2024
Two polymorph modifications of tris(hexafluoroacetylacetonato)iron(III) revealed: is that common for other trivalent metals?
Authors: Chang Joyce , Defeo Julianna N. , Wei Zheng , Dikarev Evgeny V.
Published: August 2024

A long-standing issue about the correct identification of an important starting reagent, iron(III) hexafluoroacetylacetonate, Fe(hfac)3 (1), has been resolved. The tris-chelated mononuclear complex was found to crystallize in two polymorph modifications which can be assigned as the low-temperature (1-L) monoclinic P21/n and the high-temperature (1-H) trigonal P\overline{3}. Low-temperature polymorph 1-L was found to transform to 1-H upon sublimation at 44 °C. Two modifications are clearly distinguished by powder X-ray diffraction (PXRD), single-crystal X-ray diffraction, differential scanning calorimetry (DSC), and melting-point measurements. On the other hand, the two forms share similar characteristics in direct analysis in real-time mass spectrometry (DART-MS), attenuated total reflection (ATR) spectroscopy, and some physical properties, such as color, volatility, sensitivity, and solubility. Analysis of the literature and some of our preliminary data strongly suggest that the appearance of two polymorph modifications for trivalent metal (both transition and main group) hexafluoroacetylacetonates is a common case for several largely used complexes not yet accounted for in the crystallographic databases.
Synthesis, crystal structure and Hirshfeld surface analysis of [Cu(H2
L)2(μ-Cl)CuCl3]·H2O [H2
L = 2-hydroxy-N′-(propan-2-ylidene)benzohydrazide]
Authors: Boulguemh Imededdine , Lehleh Asma , Beghidja Chahrazed , Beghidja Adel
Published: August 2024

The present study focuses on the synthesis and structural characterization of a novel dinuclear CuII complex, [trichloridocopper(II)]-μ-chlorido-{bis[2-hydroxy-N′-(propan-2-ylidene)benzohydrazide]copper(II)} monohydrate, [Cu2Cl4(C10H12N2O2)2]·H2O or [Cu(H2
L)2(μ-Cl)CuCl3]·H2O [H2
L = 2-hydroxy-N′-(propan-2-ylidene)benzohydrazide]. The complex crystallizes in the monoclinic space group P21/n with one molecule of water, which forms interactions with the ligands. The first copper ion is penta-coordinated to two benzohydrazine-derived ligands via two nitrogen and two oxygen atoms, and one bridging chloride, which is also coordinated by the second copper ion alongside three terminal chlorines in a distorted tetrahedral geometry. The arrangement around the first copper ion exhibits a distorted geometry intermediate between trigonal bipyramidal and square pyramidal. In the crystal, chains are formed via intermolecular interactions along the a-axis direction, with subsequent layers constructed through hydrogen-bonding interactions parallel to the ac plane, and through slipped π–π stacking interactions parallel to the ab plane, resulting in a three-dimensional network. The intermolecular interactions in the crystal structure were quantified and analysed using Hirshfeld surface analysis. Residual electron density from disordered methanol molecules in the void space could not be reasonably modelled, thus a solvent mask was applied.
Unveiling success factors for implementing and sustaining circular economy practices in small and medium-sized firms: multi-level perspective
Authors: Ahmadov Tarlan , Durst Susanne , Gerstlberger Wolfgang
Published: August 2024

Purpose

This study aims to identify and understand critical success factors for implementing and sustaining circular economy (CE) practices in manufacturing small and medium-sized enterprises (SMEs). More precisely, this study examines the complex interplay between micro-, meso- and macro-level success factors that are deemed critical for implementing and sustaining CE practices.

Design/methodology/approach

The study is based on a two-stage methodology that combines a comprehensive literature review and an interview study with 12 Swedish manufacturing SMEs that implement CE practices.

Findings

The study identifies and categorizes success factors for implementing and sustaining CE practices in manufacturing SMEs. Based on the findings, a holistic framework is proposed that takes into account multiple perspectives, i.e. at the micro, meso and macro levels. This framework enables a deeper understanding and thus a more nuanced discussion of the complexity inherent in the transition to a CE from the perspective of manufacturing SMEs.

Originality/value

This study contributes to the growing body of research on CE transition. By focusing on SMEs in particular, the paper adds the needed diversity to the study of CE practices and influencing factors at different levels.
A systematic review of information and communication technologies (ICTs) on student motivation: researchers’ reflections on a selected higher education institution (HEIs)
Authors: Nhleko Nhlanhla Mzameleni , Aroba Oluwasegun Julius , Chisita Collence Takaingenhamo
Published: August 2024

Purpose

Through the review of several journal articles on the adoption of information and communication technologies (ICTs) and how it impacts students’ motivation to continue with their studies or to drop out of their academic program, this study aims to review the literature on the impact of ICTs on student motivation at a university.

Design/methodology/approach

This paper is based on a systematic literature review steered by the PRISMA guidelines. This paper uses both Durban University of Technology subscription-based and publicly available papers. The research articles examined were published between 2018 and 2023 in Scopus, Web of Science and ScienceDirect.

Findings

Reviewed literature bespeaks that ICTs can increase student motivation by enhancing interactive, engaging and individualized learning. Digital technologies that engage students and offer a more engaging learning environment include instructional apps, online simulations and multimedia content. Using ICTs may be useful in lowering university dropout rates.

Originality/value

The systematic review yielded valuable insights for both academic research and real-world applications in education regarding the Durban University of Technology. The study offers a comprehensive analysis of the nexus between ICTs and student motivation.
A conceptual soft skills competency framework for enhancing graduate intern employability
Authors: Bisschoff Zelda S. , Massyn Liezel
Published: August 2024

Purpose

The paper aims to close a literature gap by proposing a comprehensive conceptual soft skills competency framework for enhancing graduate intern employability through the cultivation of employability capital.

Design/methodology/approach

The study employed a theoretical inquiry and delved into the existing literature on employability, soft skills competencies and employability capital to establish a comprehensive foundation to formulate the conceptual framework. A content analysis of existing empirical studies was conducted to derive a generic list of employers’ required soft skills. A Delphi technique was employed to harness expert consensus and insights into the derived framework.

Findings

Employability capital can be cultivated in the setting of work-integrated learning programmes and synergised through emotional and social intelligence interventions to enhance soft skills competency and graduate employability.

Research limitations/implications

The soft skills identified may overlook other important skills required by employers. Increasing participation in the Delphi study could yield additional valuable insights. Validation of the framework is needed in practical settings to understand its effectiveness and applicability to real-world organisational needs.

Practical implications

This study significantly enhances understanding of the role of employability capital in soft skills competency development and graduate employability through work-integrated learning programs and self-development. In addition, the framework has the potential to positively impact the employer-employee relationship.

Originality/value

The key theoretical contribution is a soft skill development framework that offers employers and graduates a means to identify and address deficiencies through WIL and self-development.
Learning designs that empower: navigating sandbox data science at the intersection of computing, big data and social media
Authors: Barany Amanda , Scarola Andi Danielle , Acquah Alex , Reza Sayed Mohsin , Johnson Michael A. , Walker Justice
Published: August 2024

Purpose

There is a need for precollege learning designs that empower youth to be epistemic agents in contexts that intersect burgeoning areas of computing, big data and social media. The purpose of this study is to explore how “sandbox” or open-inquiry data science with social media supports learning.

Design/methodology/approach

This paper offers vignettes from an illustrative youth study case that highlights the pedagogical prospects and obstacles tied to designing for open-ended inquiry with computational data science to access or “scrape” Twitter/X. The youth case showcases how social media can be taken up productively and in ways that facilitate epistemological agency, an approach where individuals actively shape understanding and knowledge-creation processes, highlighting the potentially transformative impact this approach might have in empowering learners to engage productively.

Findings

The authors identify three key affordances for learning that emerged from the illustrative case: (1) flexible opportunities for content-specific domain mastery, (2) situated inquiry that embodies next-generation science practices and (3) embedded computational skill development. The authors discuss these findings in relation to contemporary education needs to broaden participation in data science and computing.

Originality/value

To address challenges in current data science education associated with supporting sustained and productive engagement in computing-based data science, the authors leverage a “sandbox” approach – an original pedagogical framework to support open inquiry with precollege groups. The authors demonstrate how “big data” drawn from social media with high school-aged youth supports learning designs and outcomes by emphasizing learner interests and authentic practice.
Low-SAPS additives for lubrication in next-generation vehicles
Authors: He Xin , Chretien Christelle , Weathers Thomas , Burel Celine , Gody Guillaume , Back Olivier
Published: August 2024

Purpose

The purpose of this study is to create sustainable additives for future vehicles, characterized by low levels of sulfated ash, sulfur and phosphorus (SAPS) or even SAPS-free alternatives. These newly developed additives must not only match or outperform the current commercial benchmarks in terms of tribological performance, but also align with the emerging sustainability trends. It is anticipated that this innovative technology will yield promising outcomes in the realm of hybrid and electric vehicles.

Design/methodology/approach

This research primarily focused on chemical synthesis, performance evaluation and characterizations. These aspects were studied through collaboration between Syensqo, Southwest Research Institute (the USA) and the Lab of the Future in France. The data was generated and analyzed by a team of research scientists, internship students and technical specialists.

Findings

Two types of additives have been specifically designed and synthesized in accordance with sustainable requirements. Both technologies have exhibited exceptional frictional and wear-resistant properties. Moreover, the leading candidates exhibit a lower rate of copper corrosion, stable electric conductivity and outstanding thermal stability when compared to commercial benchmarks. This study is expected to open a new research avenue for developing next-generation additives for lubricants, with wide potential applications including hybrid electric vehicle and electric vehicle markets.

Originality/value

In the current lubricant market, there is a lack of effective low-SAPS or SAPS-free additives. This research aims to address this gap by designing sustainable additives for next-generation vehicles that not only meet specific requirements but also maintain optimal lubrication performance.

Peer review

The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-01-2024-0033/
The effect of corporate governance on financial fragility in non-financial companies: a Minskyian approach
Authors: Khatatbeh Ibrahim N. , Samman Hamdi W. , Al Salamat Wasfi A. , Meqbel Rasmi
Published: August 2024

Purpose

This study aims to examine the effect of corporate governance (CG) mechanisms on financial fragility in non-financial corporations, using Nishi’s operationalization of Minsky’s financial instability hypothesis. Specifically, the study investigates the influence of board size, board independence, CEO duality and audit quality on the financial fragility of non-financial companies (NFCs).

Design/methodology/approach

Using a panel logit regression model, the authors analyse annual data from (66) NFCs listed on the Amman Stock Exchange, spanning over the period 2015–2021. This methodology enables us to assess the relationships between the identified CG mechanisms and the categorical proxy of financial fragility.

Findings

The findings of this study reveal that a large share of NFCs fall within Minsky’s “Ponzi” classification, indicating elevated levels of financial vulnerability. Remarkably, the analysis demonstrates that larger board sizes and the CEO-Chairman duality exacerbate financial fragility within these firms. Conversely, the study results suggest that board independence and audit quality exhibit limited effects on financial fragility. In addition, profitability, firm size and financial leverage are identified as key predictors of financial fragility.

Originality/value

This study adds to the current literature by using a financial fragility index grounded in Minsky’s financial instability hypothesis. The constructed index is then used to examine specific CG factors in relation to financial fragility, which offers new insights into the dynamics influencing the default exposure of NFCs. Furthermore, the study findings have direct implications for policymakers and stakeholders aiming to enhance CG practices and foster financial stability in the private sector.
Defense supply chain collaboration: an exploratory study and empirical framework
Authors: Loska David , Genchev Stefan , Rich Nicholas , Malik Tegwen
Published: August 2024

Purpose

Considering the size and intricate nature of defense supply chains (DSC), there exists a need for a conceptual understanding regarding the precise dynamics of collaboration among the various participants engaged in these chains. This paper seeks to address the gap by investigating the practices that enable or inhibit collaborations and the development of new competencies to effectively employ a flexible response to temporary or more sustained surges in demand. Ultimately, the study aims to develop a theoretical framework relevant to the practical implementation and scholarly examination of contemporary military supply chains.

Design/methodology/approach

Semi-structured interviews were conducted with 51 DSC professionals in 7 embedded cases within an enterprise framework. The resulting transcripts were analyzed using constructs and concepts from a supply chain logistics (SC/L) literature analysis and synthesis relevant to our research purpose. Finally, the results were validated by an industry focus group with 12 participants representing the government, military, industry, and academia.

Findings

This research produced empirical generalizations that provide in-depth and systematic exploratory insights into collaboration’s meaning and characteristics within the DSC context. This study culminates by introducing a conceptual model and definition of defense supply chain collaboration (DSCC) and concludes by proposing future research directions.

Originality/value

This study makes a novel and empirical contribution to the SC/L body of knowledge by investigating embedded cases through unique access to informants within an enterprise framework that focuses on the antecedent influencing factors of collaboration within the contextual domain of the DSC and positions a future research agenda.
A multiobjective mathematical model for a novel buy-back coordination contract in the symbiotic supply chain with fuzzy price: a data-driven decision approach
Authors: Belghand Mobina , Asadi Amirhosein , Alipour-Vaezi Mohammad , Jolai Fariborz , Aghsami Amir
Published: August 2024

Purpose

The purpose of this study is developing a new buy-back coordination contract in the symbiotic supply chain. In this new contract, the goal of the supply chain members (profit maximization) is realized.

Design/methodology/approach

This paper encourages the manufacturer to order products optimally by presenting a new buy-back coordination contract, and in return, the supplier undertakes to buy the unsold products from the manufacturer at the buy-back price. By using data-driven decision-making and multiobjective decision-making and considering the existing conditions in the symbiosis industry, a contract has been presented that guarantees the profits of supply chain members.

Findings

In this paper, it was found out how the authors can determine the order quantity, buy-back price and wholesale price in a symbiotic supply chain in such a way that it makes a profit for both the supplier and the manufacturer. In other words, how to determine these variables to encourage the manufacturer to order more quantity to the supplier so that both will benefit.

Originality/value

To the best of the authors’ knowledge, this is the first paper that defines a new buy-back coordination contract in the symbiotic supply chain by considering uncertain demand and a multiobjective model. Due to the importance of environmental issues, the sharing of resources by companies and organizations with each other, and the necessity of their cooperation, industries are moving toward a symbiosis industry.
Customer gratitude expressions and FLEs’ prosocial behavior: insights from delighted customers
Authors: Tremblay Michel
Published: August 2024

Purpose

This study aims to investigate the impact of customers’ delight on the likelihood of frontline employees (FLEs) receiving expressions of gratitude from customers, as well as the subsequent effects on their customer-focused and coworker-focused behaviors. Additionally, it examines how customer orientation moderates the relationship between FLE’s likelihood of receiving customer gratitude expressions and their performance behaviors.

Design/methodology/approach

The study used a sample from a Canadian retailer specializing in the sale of artistic and creative materials for artists, crafters and hobbyists. Longitudinal data was collected through a survey administered to frontline employees, unit managers and customers, spanning 7 assessment waves over a 12-month period. In total, the data set comprised 1,609 individual observations and 3,533 customers nested within 35 business units. The hypotheses were tested by using a multilevel longitudinal modeling approach.

Findings

This research has yielded important insights. First, significant relationships emerged between enhanced customers’ delight and an increased likelihood of FLEs receiving expressions of gratitude from customers. Second, gratitude expressions received from customers were found to be positively associated with prosocial behaviors toward both customers and coworkers. Third, the findings indicate that the impact of receiving customer gratitude expressions on FLEs’ performance behaviors is more pronounced for employees with a high level of customer orientation.

Practical implications

This study highlights the importance of investing in relationship-building strategies aimed at enhancing customers’ delight. This can motivate customers to express their gratitude toward service employees and to elicit higher prosocial behaviors from employees.

Originality/value

This study offers theoretical insights into gratitude, customer behaviors and employee performance in the retail industry. A pivotal contribution of this study to marketing literature lies in its paradigm shift, redirecting attention from the traditional examination of firm-customer relationships to a nuanced exploration of customer–employee relationships.
Exploring the mutual relationships of brand equity in the tourism and hospitality sector
Authors: Huang Yung-Chuan
Published: August 2024

Purpose

The purpose of current study aims to provide a different perspective on customer-based brand equity (CBBE) and integrate this with previous brand equity theory to contribute to the brand equity literature.

Design/methodology/approach

Proposed hypotheses were verified using structural equation modelling (SEM) with multiple datasets. Study 1 collected data from 574 foreign tourists and 624 domestic tourists of culinary tourism. Study 2 used 1,020 customers from anti-epidemic restaurants, and Study 3 investigated 464 hotel customers’ perceptions of customer-based brand equity.

Findings

Building on the mediation-moderation model, the present study posits that perceived quality relates to brand loyalty through brand image and brand awareness of using 2,682 participants. Specifically, we argue that this indirect relationship exhibits a difference moderated pattern in which motivation and hedonic function are most likely to benefit from revisit destinations for tourists when they are moderate. We further explored the new anti-epidemic concepts of COVID-19 and identified restaurant operation as an important moderator that influences customer image of restaurant revisit.

Originality/value

Until now, no tourism and hospitality studies have addressed these unsolved problems in an integrated manner. This study was to investigate the brand equity development process.
What is the experience of engaging in mentalization-based treatment? A meta-ethnography of client perspectives of the therapeutic process and outcome
Authors: O’Leary Niamh , Ryan Christian , Moore Philip
Published: August 2024

Purpose

Mentalization-based treatment (MBT) is a psychotherapeutic approach that aims to increase mentalizing capacity. The purpose of this meta-ethnography was to synthesize the available qualitative literature on MBT to allow for a more thorough understanding of the lived experience of those who have undergone this therapy.

Design/methodology/approach

A systematic search of seven databases was carried out. The Critical Appraisal Skills Programme was used to appraise the papers suitable for inclusion. The data were synthesized using a meta-ethnographic approach in which the second-order constructs from each paper were translated and reinterpreted creating a line of argument synthesis.

Findings

A total of 11 studies were included in the meta-ethnography. Three overarching themes were identified within the included papers which outlined that participant experience of MBT consisted of three different developmental stages. Navigating the therapeutic process describes the participant’s experience of the therapeutic process of MBT. The processes of change in MBT outlined participant reports of mechanisms of change experienced in MBT. Mentalizing self and others described the experience of generalizing new knowledge and skills to the world outside of therapy and unveiled the impact that engaging in MBT had on participants.

Originality/value

This meta-ethnography offers new insights into how clients experience MBT as a therapeutic process and offers suggestions for implementation in clinical practice as well as areas of focus for research of this therapeutic approach.
Hybrid ferrofluid flow on a stretching sheet with Stefan blowing and magnetic polarization effects in a porous medium
Authors: Chouhan Kiran Kunwar , Chaudhary Santosh
Published: August 2024

Purpose

This study investigates the behavior of viscous hybrid ferromagnetic fluids flowing through plain elastic sheets with the magnetic polarization effect. It examines flow in a porous medium using Stefan blowing and utilizes a versatile hybrid ferrofluid containing MnZnFe2O4 and Fe3O4 nanoparticles in the C2H2F4 base fluid, offering potential real-world applications. The study focuses on steady, laminar and viscous incompressible flow, analyzing heat and mass transfer aspects, including thermal radiation, Brownian motion, thermophoresis and viscous dissipation with convective boundary condition.

Design/methodology/approach

The governing expression of the flow model is addressed with pertinent non-dimensional transformations, and the finite element method solves the obtained system of ordinary differential equations.

Findings

The variations in fluid velocity, temperature and concentration profiles against all the physical parameters are analyzed through their graphical view. The association of these parameters with local surface friction coefficient, Nusselt number and Sherwood number is examined with the numerical data in a table.

Originality/value

This work extends previous research on ferrofluid flow, investigating unexplored parameters and offering valuable insights with potential engineering, industrial and medical implications. It introduces a novel approach that uses mathematical simplification techniques and the finite element method for the solution.
Unfolding entrepreneurial resourcefulness: a systematic literature review
Authors: Lange Francie , Hesse Lukas , Kanbach Dominik K. , Kraus Sascha
Published: August 2024

Purpose

Literature on entrepreneurial resourcefulness (ER) has grown constantly in the last two decades. ER is a construct that describes the specific behavior of entrepreneurs, focusing on the generation and deployment of resources to pursue an opportunity. Since the ER literature has expanded and diversified, the purpose of this study is to integrate its findings with existing knowledge about the construct.

Design/methodology/approach

The study applies a systematic literature review approach, following the methodology of Tranfield et al. (2003). The authors identify and synthesize 31 studies focusing on ER.

Findings

The literature on ER can function on four different levels: (1) individual, (2) organizational, (3) contextual, and (4) effectual level. Studies on ER concentrate on either the individual or the organizational level, with the contextual and effectual levels appearing as additional study categories for the studies. Behind this categorization, research views ER either as an antecedent influencing a specific effect or as an outcome resulting from a particular context.

Originality/value

This paper is the first of its nature, structuring the existing ER research and proposing a research agenda on ER with seven concrete research avenues and their research questions. Based on the systematic literature review, the authors develop a framework consolidating the interrelations of the different levels.
Two-sample Mendelian randomization study: iron deficiency anemia increases the risk of epilepsy
Authors: Tong Yu , Liu Xianyun , Yang Wenqi , Qin Ningxiang , Peng Xi
Published: August 2024

Purpose

Iron deficiency anemia (IDA) is the most common form of anemia in the world, affecting children, women and the elderly, while also being a common comorbidity in several medical conditions. Several studies have suggested a possible association between IDA and neurological dysfunction. Epilepsy, one of the common neurological disorders, has an unknown association with IDA. This pa per aims to investigate whether there is a causal relationship between IDA and epilepsy using a two-sample Mendelian randomization (MR) design.

Design/methodology/approach

This paper obtained summary data on IDA and epilepsy from the FinnGen consortium. Genetic variants significantly associated with IDA were used as instrumental variables (IVs). Epilepsy, focal epilepsy and generalized epilepsy were the outcomes. This paper used inverse variance weighted (IVW) as the primary estimate, and other MR methods were used as supplementary measures. Sensitivity analysis was also performed to assess heterogeneity and pleiotropy.

Findings

IVW estimates genetically predicted a causal relationship between IDA and the risk of epilepsy [odds ratio (OR), 1.15; 95% confidence interval (95% CI), 1.05–1.26; p = 0.002] and focal epilepsy (OR, 1.978, 95% CI, 1.58–2.48, p ≤ 0.0001), while no significant causal relationship was found with generalized epilepsy (OR, 1.1, 95% CI, 0.94–1.3, p = 0.24). There was no evidence of horizontal pleiotropy and heterogeneity in the sensitivity analysis.

Originality/value

This two-sample MR study found that IDA has a negative effect on the development of epilepsy. Clinical control of IDA may be helpful in the prevention of epilepsy. There is a need for further studies to explain the underlying mechanisms of this association.
A bibliometric analysis of thematic developments in street-level bureaucracy research
Authors: Santoso Anang Dwi , Lionardo Andries
Published: August 2024

Purpose

Street-level bureaucracy (SLB) has been essential to public administration in executing government policies and shaping public service quality. This paper aims to uncover the knowledge gaps and ongoing challenges to inform future analysis on SLB.

Design/methodology/approach

This literature review analyzes the publications on SLB between 1971 and 2023 by using various bibliometric methods, including trend analysis, network co-occurrence, and thematic evolution from 994 journal articles extracted from the Scopus database.

Findings

Research on SLB has shifted focus from specific issues such as work efficiency in the early 2000s to broader themes like governance methods, policy implementation, social policy, and public service delivery. This change reflects the adaptation of the field to global challenges and policy evolutions. International collaborations have contributed to the evolution, enriching SLB discourse with cross-cultural insights and comparative analyses. The partnerships have led to innovative strategies and models to address the challenges faced by SLB, enhancing public service delivery and policy implementation.

Originality/value

This paper shows the need to integrate the shift in SLB from specific practices to broader administrative themes with the global insights from international collaborations. In underrepresented regions, such as Africa, Latin America, and Southeast Asia, research is suggested to enrich the global understanding of SLB.
Why they rot: a global epidemic impacting employees
Authors: Bilderback Stephanie
Published: August 2024

Purpose

This paper aims to explore “rotting” in the workplace, characterized by antisocial hibernation, where employees become isolated and disengaged. The study examines underlying factors and provides actionable insights and practical interventions to address “rotting” and restore a healthy work environment, empowering readers with the means to make positive changes.

Design/methodology/approach

The research integrates various theories of employee behavior, including Maslow’s hierarchy of needs, Herzberg’s two-factor theory, the job demands-resources model, cognitive load theory, distraction-conflict theory and engagement theory. By connecting these frameworks with practical HR strategies, the paper ensures a comprehensive understanding of employee isolation, instilling confidence in the research’s depth.

Findings

Employee isolation and disengagement significantly challenge organizational health and productivity. The study identifies key factors such as poor management practices, lack of social support, high job demands and inadequate communication channels. Addressing these factors through supportive environments, effective communication and mental health support can enhance engagement and reduce isolation.

Originality/value

This paper offers an innovative perspective on employee rotting by integrating multiple theoretical frameworks and practical HR strategies. It emphasizes the urgent need to address employee isolation, especially with increasing remote work and digital communication.
The Portuguese version of the societal attitudes towards autism (SATA) scale: Psychometric properties, confirmatory factor analysis and reliability
Authors: Fonseca Hugo , Manão Andreia A. , Lemos Laura , Cunha Marina , Carreiras Diogo
Published: August 2024

People with autism spectrum disorders (ASD) face discriminatory behaviours based on their condition, a consequence of prevailing negative attitudes in society. The main goal of this study was to adapt and validate the Societal Attitudes Towards Autism scale (SATA) for the Portuguese population. Additionally, we intended to examine possible factors that may influence current attitudes towards ASD. Participants were 377 adults from the general Portuguese population, with an average age of 38.55 years. The sample was collected online using self‐reported questionnaires. Starting from the original factorial structure, four SATA models were tested. The final model showed adequate fit. This unifactorial model comprised 12 items, with two correlated error pairs. The internal consistency of the total scale was acceptable (α = 0.79), and the convergent validity was confirmed by significant correlations between the SATA and compassion, and empathy. Findings suggested temporal stability was adequate. Women aged 31 to 45 years, with more knowledge of and contact with ASD, and with an autistic family member, showed more positive attitudes towards ASD. The SATA seems to be a valid and reliable scale to measure the attitudes of the Portuguese population towards ASD.
Veillonella parvula promotes root caries development through interactions with Streptococcus mutans and Candida albicans
Authors: Li Guo , Liu Yuqiu , Zhang Mengdie , Ning Jia , Wu Linrui , Jian Lixiang , Wu Hongkun , Cheng Xingqun
Published: August 2024

Root caries is a subtype of dental caries that predominantly impacts older adults. The occurrence and progression of root caries are associated with the homeostasis of dental plaque biofilm, and microbial synergistic and antagonistic interactions in the biofilm play a significant role in maintaining the oral microecological balance. The objective of the current study was to investigate the role of Veillonella parvula in the microbial interactions and the pathogenesis of root caries. The analysis of clinical samples from patients with/without root caries revealed that Veillonella and V. parvula were abundant in the saliva of patients with root caries. More importantly, a significantly increased colonization of V. parvula was observed in root carious lesions. Further in vitro biofilm and animal study showed that V. parvula colonization increased the abundance and virulence of Streptococcus mutans and Candida albicans, leading to the formation of a polymicrobial biofilm with enhanced anti‐stress capacity and cariogenicity, consequently exacerbating the severity of carious lesions. Our results indicate the critical role of V. parvula infection in the occurrence of root caries, providing a new insight for the etiological investigation and prevention of root caries.
Cooperative nuclear action of RNA‐binding proteins PSF and G3BP2 to sustain neuronal cell viability is decreased in aging and dementia
Authors: Takayama Ken‐ichi , Suzuki Takashi , Sato Kaoru , Saito Yuko , Inoue Satoshi
Published: August 2024

Dysfunctional RNA‐binding proteins (RBPs) have been implicated in several geriatric diseases, including Alzheimer's disease (AD). However, little is known about the nuclear molecular actions and cooperative functions mediated by RBPs that affect gene regulation in sporadic AD or aging. In the present study, we investigated aging‐ and AD‐associated changes in the expression of PSF and G3BP2, which are representative RBPs associated with sex hormone activity. We determined that both PSF and G3BP2 levels were decreased in aged brains compared to young brains of mice. RNA sequencing (RNA‐seq) analysis of human neuronal cells has shown that PSF is responsible for neuron‐specific functions and sustains cell viability. In addition, we showed that PSF interacted with G3BP2 in the nucleus and stress granules (SGs) at the protein level. Moreover, PSF–mediated gene regulation at the RNA level correlated with G3BP2. Interestingly, PSF and G3BP2 target genes are associated with AD development. Mechanistically, quantitative reverse transcription‐polymerase chain reaction (qRT‐PCR) analysis demonstrated that the interaction of RBPs with the pre‐mRNA of target genes enhanced post‐transcriptional mRNA stability, suggesting a possible role for these RBPs in preserving neuronal cell viability. Notably, in the brains of patients with sporadic AD, decreased expression of PSF and G3BP2 in neurons was observed compared to non‐AD patients. Overall, our findings suggest that the cooperative action of PSF and G3BP2 in the nucleus is important for preventing aging and AD development.
Benefit delayed immunosenescence by regulating CD4+T cells: A promising therapeutic target for aging‐related diseases
Authors: Xia Tingting , Zhou Ying , An Jiayao , Cui Zhi , Zhong Xinqin , Cui Tianyi , Lv Bin , Zhao Xin , Gao Xiumei
Published: August 2024

CD4+T cells play a notable role in immune protection at different stages of life. During aging, the interaction between the body's internal and external environment and CD4+T cells results in a series of changes in the CD4+T cells pool making it involved in immunosenescence. Many studies have extensively examined the subsets and functionality of CD4+T cells within the immune system, highlighted their pivotal role in disease pathogenesis, progression, and therapeutic interventions. However, the underlying mechanism of CD4+T cells senescence and its intricate association with diseases remains to be elucidated and comprehensively understood. By summarizing the immunosenescent progress and network of CD4+T cell subsets, we reveal the crucial role of CD4+T cells in the occurrence and development of age‐related diseases. Furthermore, we provide new insights and theoretical foundations for diseases targeting CD4+T cell subsets aging as a treatment focus, offering novel approaches for therapy, especially in infections, cancers, autoimmune diseases, and other diseases in the elderly.
The effect of materialism on unethical behaviour: The mediating role of self‐control
Authors: Yue Lei , Zeng Xiangli , Li Jing
Published: August 2024

Self‐enhancement values (power, achievement, and hedonism) have been found to be important predictors of ethical behaviour; however, the link between materialism (also a kind of self‐enhancement value) and unethical behaviour and its underlying mechanisms have received limited attention from researchers. The present research examines the effect of materialism on unethical behaviour and the mediating role of self‐control across five multi‐method studies with Chinese samples. Using Chinese data from the Sixth World Values Survey, we confirmed that materialism was positively related to a variety of unethical behaviours such as fare evasion, theft, tax evasion, bribery, domestic violence, and violence against others (Study 1). In follow‐up experiments, priming materialism increased unethical behaviour (Studies 2 and 3). Moreover, through a questionnaire survey, we found that self‐control played a mediating role between materialism and unethical behaviour in specific social contexts (Study 4). Finally, the manipulation of high materialists' self‐control reduced their unethical behaviour, further verifying the mediating role of self‐control (Study 5). Our findings indicate that materialists tend to have lower levels of self‐control, thus they are more likely to engage in unethical behaviours. This research supports the hot/cool system model of self‐control and deepens our understanding of how materialism might lead to unethical behaviour.
A meta‐analysis of perfusion parameters affecting weight gain in ex vivo perfusion
Authors: Marlar Riley , Abbas Fuad , Obeid Rommy , Frisbie Sean , Ghazoul Adam , Rezaee Ava , Sims Jack , Rampazzo Antonio , Bassiri Gharb Bahar
Published: August 2024

Background

Ex vivo machine perfusion (EVMP) has been established to extend viability of donor organs. However, EVMP protocols are inconsistent. We hypothesize that there is a significant relationship between specific parameters during EVMP and perfusion outcomes.

Methods

A meta‐analysis of literature was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta‐Analysis (PRISMA) Statement. The search encompassed articles published before July 25, 2023. PubMed, Embase, and CENTRAL databases were screened using search terms “ex‐vivo,” “ex‐situ,” “machine,” and “perfusion.” Weight gain, an indicator of organ viability, was chosen to compare outcomes. Extracted variables included perfused organ, warm and cold ischemia time before perfusion, perfusion duration, perfusate flow, pressure, temperature, perfusate composition (presence of cellular or acellular oxygen carrier, colloids, and other supplements) and percent weight change. Data were analyzed using SPSS statistical software.

Results

Overall, 44 articles were included. Red blood cell‐based perfusates resulted in significantly lower weight gain compared to acellular perfusates without oxygen carriers (11.3% vs. 27.0%, p < 0.001). Hemoglobin‐based oxygen carriers resulted in significantly lower weight gain compared to acellular perfusates (16.5% vs. 27%, p = 0.006). Normothermic perfusion led to the least weight gain (14.6%), significantly different from hypothermic (24.3%) and subnormothermic (25.0%) conditions (p < 0.001), with no significant difference between hypothermic and subnormothermic groups (24.3% vs. 25.0%, p = 0.952). There was a positive correlation between flow rate and weight gain (ß = 13.1, R = 0.390, p < 0.001).

Conclusions

Oxygen carriers, low flow rates, and normothermic perfusate temperature appear to improve outcomes in EVMP. These findings offer opportunities for improving organ transplantation outcomes.
Dicloxacillin is an inducer of intestinal P‐glycoprotein but neither dicloxacillin nor flucloxacillin increases the risk of stroke/systemic embolism in direct oral anticoagulant users
Authors: Iversen Ditte B. , Dunvald Ann‐Cathrine Dalgård , Ernst Martin Thomsen , Abtahi Shahab , Souverein Patrick , Klungel Olaf , Jeppesen Glenn Brøde , Nielsen Flemming , Brøsen Kim , Hammer Helen S. , Pötz Oliver , Damkier Per , Järvinen Erkka , Pottegård Anton , Stage Tore B.
Published: August 2024

Aim

We aimed to assess if dicloxacillin/flucloxacillin reduces the therapeutic efficacy of direct oral anticoagulants (DOACs) and the underlying molecular mechanism.

Methods

In a randomized, crossover study, we assessed whether dicloxacillin reduces oral absorption of drugs through P‐glycoprotein (P‐gp) during 10 and 28 days of treatment. To study the impact of dicloxacillin/flucloxacillin on intestinal and hepatic expression of P‐gp in vitro, we usd LS174T cells and 3D spheroids of primary human hepatocytes. Finally, we used nationwide Danish health registries and the UK's Clinical Practice Research Datalink to estimate hazard ratios (HRs) for the risk of stroke and systemic embolism following dicloxacillin/flucloxacillin exposure among DOAC users, using phenoxymethylpenicillin and amoxicillin as active comparators.

Results

Dicloxacillin reduced the area under the curve of dabigatran to a geometric mean ratio 10 days of 0.67 (95% confidence interval [CI]: 0.42–1.1) and geometric mean ratio 28 days of 0.72 (95% CI: 0.39–1.4), suggesting reduced oral absorption via increased P‐gp expression. In vitro, dicloxacillin raised P‐gp expression in both intestinal and liver cells, while flucloxacillin only affected liver cells. In the pharmacoepidemiologic study, dicloxacillin and flucloxacillin were not associated with increased risk of stroke/systemic embolism (dicloxacillin vs. phenoxymethylpenicillin HR: 0.93, 95% CI: 0.72–1.2; flucloxacillin vs. amoxicillin HR: 0.89, 95% CI: 0.51–1.5).

Conclusions

Dicloxacillin increases expression of intestinal P‐gp, leading to reduced oral absorption of dabigatran. However, concomitant use of dicloxacillin/flucloxacillin was not associated with stroke and systemic embolism among DOAC users, suggesting no clinical impact from the drug–drug interaction between dicloxacillin/flucloxacillin and DOACs.