bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantitative Effects of Anthropogenic and Natural Factors on Heavy Metals Pollution and Spatial Distribution in Surface Drinking Water Sources in the Upper Huaihe River Basin in China
Authors: Liu Tong , Wang Mingya , Zhang Chunhui , Yang Shili , Zhang Fan , Jia Luhao , Ma Wanqi , Sui Shaobo , Liu Qingwei , Wang Mingshi
Published: July 2024

The water quality of sources in the Huaihe River Basin significantly affects the lives and health of approximately 16.7% of China’s population. Identifying and quantifying pollution sources and risks is essential for effective water resource management. This study utilized Monte Carlo simulations and Geodetector to assess water quality and eutrophication, as well as to evaluate the sources of heavy metals and the associated health risks for both adults and children. The results showed that eutrophication of water sources in Huaihe River was severe, with an overall EI value of 37.92; 67.8% of the water sources were classified as mesotrophic and 32.2% classified as eutrophic. Water quality and eutrophication levels in the southern mountainous regions were better than those in the densely populated northern areas. Adults were found to have a higher carcinogenic risk than children, whereas children faced a higher noncarcinogenic risk than adults. Cr presented the highest carcinogenic risk, affecting more than 99.8% of both adults and children at levels above 1 × 10−6 but not exceeding 1 × 10−4. The noncarcinogenic risk from metals did not surpass a level of 1, except for Pb. As was primarily influenced by agricultural activities and transportation, whereas Cd, Cr, and Pb were mainly affected by industrial activities, particularly in local textile industries such as knitting and clothing manufacturing. The analysis demonstrated that the influence of anthropogenic factors on heavy metal distribution was significantly enhanced by indirect natural factors. For example, the explanatory power of Precipitation and Road Network Density on As was 0.362 and 0.189, respectively, whereas their interaction had an explanatory power as high as 0.673. This study indicates that the geodetector method is effective in elucidating the factors influencing heavy metal distribution in water, thereby providing valuable insights into pollution sources in global drinking water.
Structural Assessment of Chlamydia trachomatis Major Outer Membrane Protein (MOMP)-Derived Vaccine Antigens and Immunological Profiling in Mice with Different Genetic Backgrounds
Authors: Roe Shea K. , Zhu Tianmou , Slepenkin Anatoli , Berges Aym , Fairman Jeff , de la Maza Luis M. , Massari Paola
Published: July 2024

Chlamydia trachomatis (Ct) is the most common cause of bacterial sexually transmitted infections (STIs) worldwide. Ct infections are often asymptomatic in women, leading to severe reproductive tract sequelae. Development of a vaccine against Chlamydia is crucial. The Chlamydia major outer membrane protein (MOMP) is a prime vaccine antigen candidate, and it can elicit both neutralizing antibodies and protective CD4+ T cell responses. We have previously designed chimeric antigens composed of immunogenic variable regions (VDs) and conserved regions (CDs) of MOMP from Chlamydia muridarum (Cm) expressed into a carrier protein (PorB), and we have shown that these were protective in a mouse model of Cm respiratory infection. Here, we generated corresponding constructs based on MOMP from Ct serovar F. Preliminary structure analysis of the three antigens, PorB/VD1-3, PorB/VD1-4 and PorB/VD1-2-4, showed that they retained structure features consistent with those of PorB. The antigens induced robust humoral and cellular responses in mice with different genetic backgrounds. The antibodies were cross-reactive against Ct, but only anti-PorB/VD1-4 and anti-PorB/VD1-2-4 IgG antibodies were neutralizing, likely due to the antigen specificity. The cellular responses included proliferation in vitro and production of IFN-γ by splenocytes following Ct re-stimulation. Our results support further investigation of the PorB/VD antigens as potential protective candidates for a Chlamydia subunit vaccine.
Equal Maintenance of Anti-SARS-CoV-2 Antibody Levels Induced by Heterologous and Homologous Regimens of the BNT162b2, ChAdOx1, CoronaVac and Ad26.COV2.S Vaccines: A Longitudinal Study Up to the 4th Dose of Booster
Authors: do Nascimento Tatiana A. , Nogami Patricia Y. , de Oliveira Camille F. , Neto Walter F. F. , da Silva Carla P. , Ribeiro Ana Claudia S. , de Sousa Alana W. , Freitas Maria N. O. , Chiang Jannifer O. , Silva Franko A. , das Chagas Liliane L. , Carvalho Valéria L. , Azevedo Raimunda S. S. , Vasconcelos Pedro F. C. , Costa Igor B. , Costa Iran B. , Barbagelata Luana S. , das Chagas Junior Wanderley D. , da Penha Junior Edvaldo T. , Soares Luana S. , Viana Giselle M. R. , Amarilla Alberto A. , Modhiran Naphak , Watterson Daniel , Casseb Lívia M. N. , Martins Lívia C. , Henriques Daniele F.
Published: July 2024

Several technological approaches have been used to develop vaccines against COVID-19, including those based on inactivated viruses, viral vectors, and mRNA. This study aimed to monitor the maintenance of anti-SARS-CoV-2 antibodies in individuals from Brazil according to the primary vaccination regimen, as follows: BNT162b2 (group 1; 22) and ChAdOx1 (group 2; 18). Everyone received BNT162b2 in the first booster while in the second booster CoronaVac, Ad26.COV2.S, or BNT162b2. Blood samples were collected from 2021 to 2023 to analyze specific RBD (ELISA) and neutralizing antibodies (PRNT50). We observed a progressive increase in anti-RBD and neutralizing antibodies in each subsequent dose, remaining at high titers until the end of follow-up. Group 1 had higher anti-RBD antibody titers than group 2 after beginning the primary regimen, with significant differences after the 2nd and 3rd doses. Group 2 showed a more expressive increase after the first booster with BNT162B2 (heterologous booster). Group 2 also presented high levels of neutralizing antibodies against the Gamma and Delta variants until five months after the second booster. In conclusion, the circulating levels of anti-RBD and neutralizing antibodies against the two variants of SARS-CoV-2 were durable even five months after the 4th dose, suggesting that periodic booster vaccinations (homologous or heterologous) induced long-lasting immunity.
Exploring Perceptions and Barriers: A Health Belief Model-Based Analysis of Seasonal Influenza Vaccination among High-Risk Healthcare Workers in China
Authors: Peng Yalan , Wang Yantong , Huang Wenzhi , Lin Ji , Zeng Qinghui , Chen Yi , Qiao Fu
Published: July 2024

The annual seasonal influenza vaccination rate among high-risk healthcare workers (HCWs) has fallen below expectations, underscoring the importance of exploring the impact of perception on vaccination behavior. An online survey, grounded in the Health Belief Model (HBM), was administered to high-risk healthcare workers at West China Hospital. The data analysis encompassed descriptive statistics, logistic regression for univariate analysis, and path regression for multivariate analysis. A total of 1845 healthcare workers completed the survey, with an acceptance rate of 83.90% (95% CI, 82.20–85.60%). Path analysis revealed significant correlations between vaccination acceptance and perceived susceptibility (β = 0.142), perceived benefits (β = 0.129), perceived barriers (β = 0.075), exposure to vaccination advertisements (β = 0.115), and knowledge about seasonal influenza (β = 0.051). Vaccination education efforts should prioritize elucidating the risks associated with the disease and emphasizing the benefits of vaccination. Furthermore, leveraging advertising proves to be an effective strategy for promotion.
Assessment of Subseasonal-to-Seasonal (S2S) Precipitation Forecast Skill for Reservoir Operation in the Yaque Del Norte River, Dominican Republic
Authors: Pelak Norman , Shamir Eylon , Hansen Theresa Modrick , Cheng Zhengyang
Published: July 2024

Operational forecasters desire information about how their reservoir and riverine systems will evolve over monthly to seasonal timescales. Seasonal traces of hydrometeorological variables at a daily or sub-daily resolution are needed to drive hydrological models at this timescale. Operationally available models such as the Climate Forecast System (CFS) provide seasonal precipitation forecasts, but their coarse spatial scale requires further processing for use in local or regional hydrologic models. We focus on three methods to generate such forecasts: (1) a bias-adjustment method, in which the CFS forecasts are bias-corrected by ground-based observations; (2) a weather generator (WG) method, in which historical precipitation data, conditioned on an index of the El Niño–Southern Oscillation, are used to generate synthetic daily precipitation time series; and (3) a historical analog method, in which the CFS forecasts are used to condition the selection of historical satellite-based mean areal precipitation (MAP) traces. The Yaque del Norte River basin in the Dominican Republic is presented herein as a case study, using an independent dataset of rainfall and reservoir inflows to assess the relative performance of the methods. The methods showed seasonal variations in skill, with the MAP historical analog method having the strongest overall performance, but the CFS and WG methods also exhibited strong performance during certain seasons. These results indicate that the strengths of each method may be combined to produce an ensemble forecast product.
Organização, gestão e cuidado nutricional de pessoas com sobrepeso e obesidade na Atenção Primária à Saúde
Authors: Mariani Karine Alves , Sena Reis Roberta , Martins Karine Anusca , Moraes Bibiana Arantes , Silva Lara Livia Santos da , Peixoto Maria do Rosário Gondim
Published: July 2024

Objetivo: Avaliar a organização, gestão e o cuidado nutricional ofertado às pessoas com sobrepeso e obesidade na Atenção Primária à Saúde (APS). Métodos: Trata-se de um estudo transversal realizado com 54 profissionais da Atenção Primária à Saúde da cidade de Goiânia-GO. Os dados foram obtidos por meio do questionário eletrônico semiestruturado e autoaplicável. Resultados: Os profissionais participantes eram enfermeiros 88,9%, e com mais de cinco anos na função atual 79,6%. Ao analisar a infraestrutura e mobiliário, apenas 11,1% relataram cadeiras e bancos adequados, 33,3% acessibilidade física. O mapeamento do território foi referido por 51,8% dos profissionais. As principais estratégias para organização do cuidado e tratamento foram: central de regulação 79,6%, referência e contrarreferência 77,8%. Conclusão: Os resultados deste estudo refletem que a APS em Goiânia-GO, está em processo de implantação da gestão e cuidado nutricional que atendam às políticas públicas previstas para a prevenção e manejo do sobrepeso e obesidade.
Management of the Russian labor market: new trends
Authors: Kulapov M. N. , Odegov Yu. G. , Uraev N. N. , Manakhov S. V.
Published: July 2024

The market as such is a social institution that facilitates the exchange of different types of goods and services. In general, the labor market should be considered as an integral part of the market economy, functioning in it along with other markets – resources, goods, securities, etc. It is a system of social relations between employers, employees and the state present on the market, reflecting and achieving a balance of interests between them for a given period, ensuring the reproduction, exchange and use of living labor. It has its own specific internal structure, the main elements of which are: the demand for labor; the supply of labor; the price of power; labor cost; competition. The transition to a market economy has led to the fact that for the bulk of the economically active population, labor has become wage-based, depending on the ratio of supply and demand and economic conditions. This is where the employee sells his workforce to the employer.

Today, the labor market is undergoing rapid changes associated with a number of global factors such as a change in technological structure, digitalization of the economy, demographic and age-related changes in the structure of the population. It adapts to external conditions, for example, the consequences and limitations of the coronavirus epidemic, creates new formats of labor relations, in particular, the format of self-employment set by national goals, and forms relevant requests to employers and job seekers, the answer to which is not always obvious. Responding to the creation of high-performance jobs, the labor market increases the proportion of atypical forms of employment, which are becoming more and more in demand as a result of more flexible legal regulation of labor relations.

The model of labor market flexibility focuses mainly not on the macro, but on the micro level, not on external, but on internal labor markets, not on quantitative, but on qualitative adaptation of employment. The International Labour Organization links modern transformations in the world of work with such areas of the economy as the informal economy, non-standard forms of work and other new forms of employment. All of them have qualities that destroy standard employment from the inside and expand non-standard employment. The consequence of this is the forced employment of large masses of workers in conditions of partial or complete loss of their labor and social rights provided for in standard employment. The International Labour Organization estimates the negative impact of precarious employment on modern employment to be higher than unemployment.
Nikolaev Ivan Romanovich: the problem of the reality of balance
Authors: Glazko A. I.
Published: July 2024

This article is devoted to the problem of determining the semantic content of balance sheet assets and the impact of this problem on the analysis of financial statements. Discussions on this issue began by Western and domestic balance specialists of the XIX– XX entury and remain relevant at the present time. Ivan Romanovich Nikolaev, one of the few proponents of dynamic balance theory among Russian balance sheet specialists of the 20th century, paid special attention to the problem of determining assets. Representing the views of accounting realism, he defended the approach according to which an asset represents the amount of costs incurred, rather than the objective value of the property. In terms of analysis, his ideas prove the futility of calculating liquidity ratios in the event that an asset is recognized as a set of expenses that have not yet been written off.
The ICC jurisdiction in Ukraine: challenges and opportunities in the fight against impunity
Authors: Lankevych Andrii , Zaverukha Oleh , Sopilnyk Rostyslav , Havrylenko Oleksandr , Podilchak Olha
Published: July 2024

This article examines the legal relationship between the International Criminal Court (ICC) and Ukraine, a non-party to the Rome Statute, focusing on the scope of the Court's jurisdiction to consider Ukraine's referrals regarding serious crimes committed on its territory since 2014. Discussions regarding the extension of the ICC's jurisdiction over Ukraine commenced in 2014-2015 following Ukraine's two requests for recognition of the ICC's ad hoc jurisdiction. Following the full-scale invasion in 2022, the ICC consolidated these proceedings with the ongoing investigation of crimes committed in Ukraine since 2014. This article analyzes how the ICC's jurisdiction applies to Ukraine, the challenges and prospects for cooperation between the ICC and Ukraine in investigating crimes committed by Russian forces, and the broader implications for the international criminal justice system. The authors analyze arguments for and against Ukraine's ratification of the Rome Statute, concluding that the ICC's jurisdictional framework, particularly concerning the crime of aggression, requires refinement.
Keterampilan Guru Mengelola Kelas dalam Meningkatkan Prestasi Belajar Siswa Kelas VI Bidang Studi Qur’an Hadits di MI NW Korleko
Authors: Masjudin Masjudin
Published: July 2024

This research aims to find out how teachers' classroom management skills improve student learning achievement. Various problems in the learning process are part of various unfinished studies discussed in various seminars, discussions and other academic activities to find various alternative solutions to problems faced by teachers in carrying out their duties as teachers and educators in school or madrasah environments.  The research method uses qualitative research and data is collected using interview, observation and documentation methods to secure the research objects in the field. The research was carried out at Madrasah Ibtida'iyah NW Korleko. The results of the research show that the classroom management carried out at the research location takes the form of classroom management skills when studying the field of Qur'an Hadith studies, namely classroom arrangement, teaching facility arrangement, student management, student management outside the classroom and classroom administration. Meanwhile, student learning achievement is still less successful because class management skills have not been implemented optimally, so there needs to be an increase in the teacher's class management skills so that student learning achievement can be even better
Gaya Kepemimpinan Kepala Sekolah Dalam Meningkatkan Motivasi Kerja Tenaga Kependidikan
Authors: Fadilah Rahmi , Ose Fitria , Idris Idris , Nellitawati Nellitawati , Yahya Yahya
Published: July 2024

The principal is the highest leader in an educational institution, has an important role in increasing the work motivation of educational staff. Leadership is the key to effective educational implementation. School principals can lead schools towards improving quality and service by choosing the right leadership style. This research examines the leadership style of school principals to increase the work motivation of educational staff. This research uses a systematic literature review. The results of this research are that the school principal's leadership style on the performance of educational staff has a big influence which includes several aspects of the principal's leadership style, namely: (a) the daily behavior of the principal shows an attitude that is caring, open, cheerful, firm, wise, disciplined and committed, as well as stable emotions; (b) assignments are distributed fairly and instructions are provided; (c) decision making is carried out collectively or jointly; and (d) appropriate and consistent supervision. To improve the performance of educational staff, school principals motivate by providing incentives and giving awards.
MANAJEMEN PENGORGANISASIAN DALAM PENDIDIKAN ISLAM
Authors: Nawawi Moh , Fatkhiyah Milatul , Sopiah Sopiah
Published: July 2024

artikel ini menyajikan tinjauan tentang konsep pengorganisasian dalam konteks dan pandangan pendidikan Islam, dengan fokus pada aspek-aspek kritis seperti konsep dasar, jenis, proses, fungsi serta manfat/tujuan, struktur organisasi. wewenang dan keskuasaan, desentralisasi dan sentralisasi, hubungan dalam organisasi, serta analisis management pengorganisasian terhadap lembaga pendidikan di indonesia. Artikel ini menggunakan metode penelitian library research  yang bersumber dari  media online akademik. Tujuan dari artikel ini diharapkan dapat memberikan wawasan bagi para praktisi pendidikan Islam dan pengambil kebijakan untuk meningkatkan pengorganisasian pendidikan mereka. Dengan pendekatan yang holistik dan berbasis nilai-nilai Islam, pengorganisasian dalam pendidikan Islam dapat menjadi landasan kuat untuk membentuk generasi yang berintegritas, berwawasan luas, dan berkomitmen pada pembangunan masyarakat yang berlandaskan nilai-nilai Islam.
MANAJEMEN KEUANGAN LEMBAGA PENDIDIKAN ISLAM
Authors: Suroso Suroso , Untung Slamet , Muslih Mohamad
Published: July 2024

Penelitian ini bertujuan untuk menjelaskan manajemen keuangan dalam konteks lembaga pendidikan Islam. Manajemen keuangan pendidikan merujuk pada proses profesional dan proporsional dalam mengatur pengelolaan keuangan yang diperuntukkan bagi program-program pelaksanaan operasional pendidikan. Manajemen keuangan merupakan bagian integral dari pengelolaan sekolah yang memiliki peran penting dalam menentukan jalannya kegiatan pendidikan di sekolah. Fokus dari penelitian ini adalah untuk memahami prinsip-prinsip dasar dalam manajemen keuangan serta bagaimana penerapannya dalam konteks lembaga pendidikan Islam. Penelitian ini dilakukan dengan menggunakan metode kualitatif dimana data diperoleh melalui penelitian perpustakaan yang bertujuan untuk memahami pesan yang terkandung dalam suatu teks. Hasil dari penelitian ini menunjukkan bahwa manajemen keuangan dalam pendidikan Islam melibatkan proses alokasi sumber daya untuk mendukung kegiatan operasional pendidikan, yang mencakup perencanaan pendanaan, implementasi anggaran pendidikan, serta pencatatan dan pemeriksaan atau pengawasan terhadap pengelolaan anggaran pendidikan. Tujuan utama dari manajemen keuangan pendidikan adalah penggunaan dana atau anggaran secara efisien dan efektif untuk mencapai tujuan pendidikan yang diharapkan.
EVALUASI PERBANDINGAN PELAKSANAAN KURIKULUM 2013 DAN KTSP PADA PEMBELAJARAN GEOGRAFI DI SMAN KOTA PADANG
Authors: Simponi Maijem , Yanto Andri , Rahayu Intan Dwi , Veni Veni , Putri Desi Eka , Sari Tiara Indah , Afrianto Nanda
Published: July 2024

Based on literature studies and researcher observations, the problems encountered in the implementation of the 2013 curriculum are reflected in the difficulty of changing teachers' mindsets, changing the learning process from teacher centered to student centered, low spiritual morals, low reading and research culture, lack of mastery of technology by teachers, weak mastery. in the field of administration, the tendency of teachers to emphasize more on cognitive aspects, there are still many teachers who do not want to become human learners, a teacher is required to continue to increase knowledge and broaden his horizons, especially after the implementation of the 2013 curriculum. These problems make the 2013 curriculum difficult for some schools to accept, including high schools spread across Padang City. Similar to other regions, Padang City also complained about learning based on the 2013 curriculum. One of the subjects affected by this curriculum change was geography.  As is the case in high school (SMA), geography learning has been given specifically since the first grade of school, while in grades two and three geography learning is only given to students who choose the Social Sciences major. The KTSP problem can be seen from the lack of creativity of teachers who are trusted as educators.
DAMPAK BUDAYA ORGANISASI TERHADAP EFEKTIVITAS KOMUNIKASI INTERNAL DI SEKOLAH MIS NURUL FADHILAH
Authors: Syahputra Muhammad Rizki , Munawwarah Tarisa , Sani Dinda Aulia , Kholizah Nur Alfiana , Siregar Nur Khofifah
Published: July 2024

Internal school communication includes various elements between students and teachers, teachers and students, teachers and students' parents and teachers and members of the school environment. Research The method used was an interview with one of the respondents, namely the MIS school teacher at Nurul Fadhilah. The method used in this research is qualitative research with a literature study approach. Research findings show that associations have an impact on the continuity of interior correspondence at the Nurul Fadhilah MIS School. The following were found to be the impacts of organizational culture: increasing employee engagement at work, job satisfaction, and motivation at work expanding the continuity of inner correspondence between leaders between organizational members and subordinates. The findings of this research indicate that an effective organization can be one that has a strong and positive communication culture, thereby improving the performance and efficiency of representatives. As a result, this research helps develop strategies. Effective communication in the MIS Nurul Fadhilah organization and other schools. The aim of this research is to find out how organizational culture influences the effectiveness of internal communication at the Nurul Fadhilah MIS School.
PENERAPAN STRATEGI MANAJEMEN KONFLIK DI LINGKUNGAN SEKOLAH: ANALISIS BERDASARKAN KAJIAN LITERATUR
Authors: Maharani Rafika , Hanif Ma’mun
Published: July 2024

This research aims to describe the implementation of conflict management strategies in the school environment based on a literature review. This research is qualitative research in the nature of library research where various books and other literature are used as the main source. Qualitative research is a research method that produces information in the form of descriptions and notes based on the text that is the focus of the research. Data collection uses the source search method and constructs it from various literature, for example books, journals and previous research results. Library materials are obtained through various references which are analyzed critically and in depth to strengthen arguments and ideas. The result of this research is that through an in-depth understanding of the literature review, we can detail concrete steps that can be taken by educational institutions to increase their capacity in managing conflict. In this way, schools can become spaces that not only provide quality education but also form good character and conflict resolution abilities in students. The literature review illustrates that implementing conflict management strategies in the school environment is an important step to increase harmony and effectiveness of educational institutions
Interim geologic map of the Fort Douglas quadrangle, Salt Lake, Davis, and Morgan Counties, Utah
Authors: Anderson Zachary W. , McKean Adam P. , Yonkee W. Adolph
Published: July 2024

The Fort Douglas quadrangle (Plate 1) is in Salt Lake, Davis, and Morgan Counties of northern Utah and covers part of Salt Lake Valley and rugged peaks and canyons of the central Wasatch Range, including the Sessions Mountains. This area straddles the Basin and Range and Middle Rocky Mountains Physiographic Provinces. Parts of the cities of North Salt Lake and Bountiful are in the northwest corner of the quadrangle. The southwest corner covers the northeast part of Utah’s capital, Salt Lake City, including parts of downtown, the Avenues Historic District neighborhood, and the University of Utah including its medical complex and research facilities. Some of these areas were the first parts of the valley settled and developed after the arrival of the Latter-Day Saints in 1847. The Wasatch Range contains steep and rugged terrain that is a critical watershed and recreation area for the population of the heavily urbanized Wasatch Front, as well as critical habitat for wildlife. Major drainages within the quadrangle are, from north to south: Mill Creek Canyon (Bountiful), North Canyon, City Creek Canyon, Dry Creek, Red Butte Canyon, and Emigration Canyon. The northeast corner of the quadrangle contains the upper reaches of Holbrook Canyon and Shingle Mill Creek, a tributary to Hardscrabble Canyon, which feeds the Weber River.
Метод k-mer у завданнях виявлення закономірних послідовностей
Authors: Терпіловський Єгор Олександрович
Published: July 2024

У статті порівнюються дві методології попередньої обробки послідовностей ДНК людини для покращення ідентифікації конкретних генетичних захворювань за допомогою методів машинного навчання. Перший підхід забезпечує вибірку слів k-mer, тоді як другий використовує Multiple EM for Motif Elicitation (MEME) для розпізнавання мотиву. Метод k-mer передбачає розбиття по­слідовності ДНК на менші фрагменти фіксованої довжини, що дозволяє структурувати та аналізувати великі обсяги даних ефективно. З іншого боку, MEME застосовує алгоритм максимізації сподівань (EM) — Expectation-Maximization для виявлення статистично значущих біологічних мотивів у послідовностях, що дає змогу глибше зрозуміти функціональні області ДНК. Всебічний аналіз передбачає тренування моделі машинного навчання на вибірках даних, оцінку точності та інші метрики продуктивності, а також можливість практичного впровадження обох методів. Дані для дослідження надані центром U.S. National Library of Medicine і репрезентовані у форматі FASTA, який забезпечує стандартизоване представлення нуклеотидних послідовностей. Кожен зразок ДНК належить людям, які дали згоду на використання їхніх генетичних матеріалів у наукових дослідженнях. Для забезпечення всебічного аналізу дані оброблені як за допомогою k-mer, так і MEME. Перший метод сумісний з різними алгоритмами машинного навчання та дозволяє ефективно обробляти великі обсяги генетичних даних, а другий є потужним інструментом для розпізнавання мотивів, але потребує значних обчислювальних ресурсів та часу для аналізу. Порівняння цих методів показало, що у контексті ідентифікації генетичних захворювань за геномними послідовностями k-mer має переваги у швидкості та ефективності, тому більш придатний для практичного застосування у клінічних умовах. Виявлено, що цей метод забезпечує також високу точність і ефективність, що робить більш доцільним його інтеграцію у клінічні системи для швидшої діагностики. Отримані висновки сприятимуть удос­коналенню підходів до генетичної діагностики та розвитку персоналізованої медицини.
CONTROLLED STOCHASTIC SYSTEMS
Authors: Knopov P.S. ,   V.M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine, knopov1@yahoo.com, Pepelyaeva T.V. ,   V.M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine, pepelaev@yahoo.com
Published: July 2024

Controlled Markov and semi-Markov processes and systems are considered. A review of inventory control problems is provided. One- and multiproduct models with different types of cost function and optimality criteria are considered. The optimality conditions and structures of optimal strategies in the problems are investigated. Keywords: Markov processes, semi-Markov processes, inventory control, (s,S )-strategy, optimality criterion, optimal strategy.
THE IMPACT OF PUBLIC PROCUREMENT ON THE STRUCTURE AND DYNAMICS OF THE NATIONAL ECONOMY
Authors: БУНТОВСКИЙ С.Ю. , СИБИРКИНА В.С.
Published: July 2024

В статье представлены результаты теоретических и методических исследований в области государственного регулирования закупками. Влияние государственных закупок на состояние экономики и поддержании ее на стабильном уровне является актуальной темой для стабильного функционирования системы управления и поддержания качества жизни населения.

The article presents the results of theoretical and methodological research in the field of state regulation of procurement. The impact of public procurement on the state of the economy and maintaining it at a stable level is an urgent topic for the stable functioning of the management system and maintaining the quality of life of the population.
MANAGEMENT OF THE POTENTIAL OF SOCIO-ECONOMIC SYSTEMS OF THE KRASNODAR REGION
Authors: ВАСИЛЬЕВА Н.К. , СИДОРЧУКОВА Е.В. , ТАРАСЕНКО Н.Г. , КРЫЖАНОВСКИЙ Д.Д.
Published: July 2024

В статье определено, что, управление социально-экономической системой региона следует рассматривать как процесс влияния на потенциал совокупности взаимосвязанных экономических субъектов с целью повышения эффективности их деятельности с применением ряда количественных и качественных показателей, характеризующих их экономический рост и развитие и состоящий из последовательных этапов: выявление, оценка, использование, развитие. При этом, каждый потенциал, входящий в систему оценивается рядом показателей, имеющих количественное и качественное выражение.

The article determines that the management of the socio-economic system of the region should be considered as a process of influencing the potential of a set of interrelated economic entities in order to increase the efficiency of their activities using a number of quantitative and qualitative indicators characterizing their economic growth and development and consisting of successive stages: identifying , evaluation, use, development. At the same time, each potential included in the system is evaluated by a number of indicators that have a quantitative and qualitative expression.
IMPROVEMENT OF PUBLIC ADMINISTRATION OF THE CROP INDUSTRY
Authors: ТИТОВА Е.П. ТИТОВА Е.П. , ОРЕХОВА М.С. ОРЕХОВА М.С. , ЧЕСЕБИЕВ А.Ю. ЧЕСЕБИЕВ А.Ю.
Published: July 2024

В статье рассмотрены направления инновационного развития растениеводства. Представлены три этапа развития освоения инноваций отраслью растениеводства. Проведена оценка наукоёмких агротехнологий в адаптивно-ландшафтных системах земледелия Краснодарского края. Дана оценка предпосевной электрофизической обработки семян. Результаты анализа могут быть использованы в процессах разработки и реализации политики регулирования сельскохозяйственной активности в системах различного уровня.

The article considers the directions of innovative development of crop production. Three stages of the development of the development of innovations by the crop industry are presented. The assessment of scienceintensive agricultural technologies in adaptive-landscape systems of agriculture in the Krasnodar Territory has been carried out. The evaluation of presowing electrophysical treatment of seeds is given. The results of the analysis can be used in the development and implementation of policies for regulating agricultural activity in systems of various levels.
Study of optical parameters of composites of different years of manufacture with temperature changes and recommended exposure time by an automated spectrophotometer
Authors: Shalamay L.I. , Mendosa E.Yu. , Maiorov E.E. , Lampusova V.B. , Oksas N.S. , Kosov S.A.
Published: July 2024

This article is devoted to the study of the optical parameters of composites of different years of manufacture with changes in temperature and exposure time by an automated spectrophotometer. It is promising to use spectrophotometers to study the optical properties of composite materials, since these devices provide reliable, reliable and highly accurate information about the object under study. The paper defines the purpose of the research, sets the task and presents the objects and method of measurements. The optical scheme and technical parameters of the device are given. Spectral dependences of the absorption coefficient K(λ) of «Estelite Asteria» samples of hue in the second axis at different exposure times and different temperatures are obtained. It was found that the exposure time t = 10 s, and temperatures (T = 0 °C, T = 47 °C), as well as the year of manufacture of the material (2020, 2021 and 2023), do not affect the quality of the restorations. Study results can be used in therapeutic dentistry, dental logistics and optical instrumentation.
PENGEMBANGAN FASILITAS PENDUKUNG UNTUK MENGOPTIMALKAN POTENSI WISATA EDUKASI KEBUN PAK AGUS
Authors: Maryo Inri Pratama  , Khala Christianto Credidi Septino , Saiid Muhammad , Ilham Muhammad , Farid Rival Ahmad , Syah Indo Rismayani Syah , Amalia Lina , Haruniah Wa Siti Nabilah , Surya Muhammad Aji , Apriliani Tiara
Published: July 2024

Kegiatan pengabdian masyarakat di Kebun Pak Agus bertujuan untuk memberikan kontribusi positif kepada masyarakat sekitar, khususnya dalam hal pengembangan potensi wisata edukasi dan keberlanjutan lingkungan. Metode pelaksanaan kegiatan pengabdian masyarakat ini terdiri dari beberapa kegiatan diantaranya adalah pembuatan website Kebun Pak Agus, penyediaan alat-alat berkebun untuk pengunjung (anak-anak sekolah), pembuatan penanda tanaman, pembuatan posteredukasi, pembuatan poster branding dan sosialisasi Kebun Pak Agus. Hasil dari kegiatan ini menunjukkan terciptanya aksesibilitas yang lebih luas bagi masyarakat untuk mengakses informasi terkait Kebun Pak Agus dan dapat membantu masyarakat terutama pengunjung dalam meningkatkan pemahaman mengenai berbagai jenis tanaman serta memperkuat citra dan kesadaran masyarakat tentang keberadaan Kebun Pak Agus sebagai sumber daya penting dalam pendidikan dan pertanian lokal.
PENGEMBANGAN DAERAH KAMPUNG PESISIR MELALUI PENINGKATAN SARANA RT.06 KLANDASAN ULU
Authors: Syah Putra Rulliannor , Alfiqri Muhammad Diva , Zainun Ahmad , Aditama Fahrudin , Putri Marshanda Aulia , Salsabila Naurah , Pangestuti Tria Puji , Santoso Mallika Putri , Artanti Tiara Harya
Published: July 2024

Facilities are facilities or tools needed to support a particular activity or activities. Developing facilities is one way to improve the quality of life of people in an area. Klandasan Ulu Village is one of the villages on the coast with a fairly dense population, but does not yet have adequate facilities for its people. The facilities in question include ablution places at local prayer rooms, alley signboards, and communal trash cans for residents. Therefore, it is necessary to develop facilities in the village to support the activities of the residents of Pesisir Village so that they can carry out their activities comfortably. The method for carrying out activities begins with discussions with local residents regarding the construction of rubbish bins, ablution places and sign boards along with their installation points. The results obtained during the activity were facilitating the community in disposing of rubbish easily, creating ablution facilities to facilitate worship activities, and creating sign boards as a useful information medium for the local community.
Problems of removing heavy metals salts from wastewater: options and solutions
Authors: Рябчиков Б.Е. , Пантелеев А.А. , Касаточкин А.С. , Ларионов С.Ю. , Шилов М.М.
Published: July 2024

На предприятиях многих отраслей промышленности образуется большой объем сточных вод, содержащих соли различных тяжелых металлов и их соединений. Разработано множество вариантов технологий, позволяющих извлекать тяжелые металлы из сточных вод: ионный обмен и мембранные технологии, а также реагентные методы. Однако в результате очистки с помощью первых двух методов образуются новые высококонцентрированные растворы токсичных компонентов, которые требуют последующего захоронения или отверждения. Реагентные методы позволяют получать отходы в виде шлама, который также необходимо обрабатывать и подвергать захоронению. В результате эти технологии часто используются совместно. Некой альтернативой являются методы очистки, основанные на интенсивном реагентном осаждении в вихревом слое в присутствии затравочного материала, обычно песка. В этом случае продуктом являются гранулы, как правило, карбоната кальция, со связанными в слое карбоната тяжелыми металлами или другими токсичными загрязнениями. Разработанная динамическая система умягчения воды (ДСУ), предназначенная для удаления карбонатной жесткости из питьевой воды, была опробована для целей удаления цветных металлов. Полученные результаты позволяют рассчитывать на высокую эффективность данного метода.

Many industrial enterprises generate large amounts of wastewater containing salts of various heavy metals and their compounds. Numerous technological options have been developed to extract heavy metals from wastewater: ion exchange and membrane technologies, as well as chemical methods. However, using the first two methods results in the generation of new highly concentrated solutions of toxic components that require subsequent landfilling or solidification. Chemical methods provide for obtaining waste in the form of sludge that also needs processing and landfilling. Consequently, these technologies are often combined. Some methods based on the intensive chemical precipitation in a vortex layer in the presence of seeding material, sand, as a rule, can be considered as an alternative. In this case, products of the process are granules, usually calcium carbonate, with heavy metals or other toxic contaminants bound in the carbonate layer. The developed dynamic water softening system (DSS), designed to remove carbonate hardness from drinking water, was tested for the purpose of removing non-ferrous metals. The results obtained allow us to expect the high efficiency of this method.
«Gute Nachrichten für uns Hyperboräer». Le lettere di Hans Magnus Enzensberger a Cesare Cases (1962-1966)
Authors: Manara Matilde
Published: July 2024

This article presents the correspondence Cesare Cases and Hans Magnus Enzensberger entertained from 1962 to 1966. Held at Centro Interdipartimentale di Ricerca Franco Fortini (University of Siena), this correspondence consists of eight letters and one postcard (all sent by Enzensberger to Cases). By analyzing and commenting on certain excerpts of their letters, we will place the two authors in their national and international contexts and provide a foreshortened picture of the relationships between German and Italian left-wing intellectuals after the Second World War.
L’ordine simbolico patriarcale in fiamme: L’arte della gioia di Goliarda Sapienza
Authors: Muraglia Giulia
Published: July 2024

This article proposes an interpretation of Goliarda Sapienza’s L’arte della gioia focused on a shaded area not analyzed by the criticism yet: the topic of patricide. The latter presents itself as the act of initiation that sets in motion the process of deflagration of patriarchy in order to create a new symbolic order – not related to the maternal order nor to the paternal one – that comes from the ashes of fire which Modesta ignites at the beginning of her existential path.
Alteraciones en el ciclo menstrual post-infección de COVID-19
Authors: Pérez Martínez María Belén
Published: July 2024

OBJETIVO: describir las alteraciones en el ciclo menstrual post-infección de COVID-19. MÉTODO: se realizó una revisión de estudios y artículos científicos recientes. RESULTADOS: actualmente se describe la enfermedad de COVID-19 como una enfermedad multisistémica, en la cual cada día se describen casos relacionados con alteraciones en el ciclo menstrual. Estas alteraciones no solamente pueden ser perjudiciales para la salud reproductiva, sino que se asocian con problemas de salud mental, cardiovascular, renales y, en general, afectan la calidad de vida de las mujeres. Las alteraciones en el ciclo menstrual pueden presentarse en cualquier paciente que haya tenido COVID-19. CONCLUSIÓN: Las alteraciones en el ciclo menstrual de la mujer luego de la infección por  COVID-19 se ha evidenciado en numerosos estudios realizados, los cuales demuestran que existen cambios en la frecuencia de los ciclos, la duración de cada ciclo y en el volumen menstrual.
Enhancing Faculty Excellence: The Impact of NEP 2020 on Training and Development of Management Educators
Authors: Prasad Dr. Nilesh Narayan
Published: July 2024

The New Education Policy (NEP) 2020 has brought significant reforms to the Indian education system, particularly in the training and development of management faculty. This paper explores the impact of NEP 2020 on enhancing the skills and competencies of management educators. The study highlights the key initiatives introduced by NEP 2020, the challenges faced in implementing these initiatives, and the overall implications for the quality of management education. The findings suggest that NEP 2020 fosters a more dynamic and effective faculty development framework, although further efforts are needed to address implementation barriers.
Sistem Pendukung Keputusan untuk Penentuan Jurusan di Sekolah Menengah Kejuruan dengan Metode SAW
Authors: HERNANDO LUKI
Published: July 2024

Penelitian ini bertujuan untuk mengembangkan Sistem Pendukung Keputusan (SPK) berbasis metode Simple Additive Weighting (SAW) untuk membantu proses penentuan jurusan di Sekolah Menengah Kejuruan (SMK). Sistem ini diharapkan dapat membantu siswa, orang tua, dan pihak sekolah dalam memilih jurusan yang tepat dan sesuai dengan potensi dan keinginan siswa. Penelitian ini menggunakan metode SAW untuk menilai berbagai kriteria seperti nilai akademik, minat dan bakat siswa, hasil tes psikologi, serta rekomendasi dari guru atau konselor Pendidikan. Data yang digunakan dalam penelitian ini adalah data siswa kelas X SMK yang terdiri dari nilai akademik, hasil tes psikologi, dan minat dan bakat siswa. Hasil penelitian menunjukkan bahwa sistem SPK berbasis metode SAW terbukti efektif dalam membantu proses penentuan jurusan di SMK. Sistem ini menghasilkan rekomendasi jurusan yang akurat dan sesuai dengan data yang digunakan. Sistem ini juga mudah digunakan dan dipahami oleh pengguna, sehingga dapat diterapkan dengan mudah di lingkungan siswa SMK.
Efektivitas Komunikasi Pembelajaran Pelatihan Model Blended Learning
Authors: Kalatasik Arniati J. , Hasanuddin Universitas , Mau Muliadi
Published: July 2024

Tujuan dari penelitian ini adalah untuk menganalisis efektivitas komunikasi pembelajaran dalam pelatihan dengan model BL. Penelitian ini menerapkan penelitian kuantitatif metode survei dengan membagikan kuesioner terdiri dari 18 pernyataan sikap dalam bentuk skala likert (Sangat Tidak Setuju, Tidak Setuju, Netral, Setuju, Sangat Setuju) yang akan dipilih oleh responden dan dibagi ke dalam 3 indikator, yakni Kemampuan Komunikasi Tenaga Pelatih, Keaktfian Peserta, dan Interaksi Pembelajaran. Hasil dari penelitian ini bahwa efektivitas komunikasi pembelajaran dalam model BL dianggap sangat tinggi oleh peserta pelatihan. Kemampuan komunikasi tenaga pelatih dinilai tinggi, menunjukkan keterampilan yang efektif dalam menyampaikan materi. Keaktifan peserta juga dinilai tinggi, menunjukkan partisipasi aktif dalam pembelajaran. Interaksi pembelajaran dinilai tinggi, menciptakan lingkungan pembelajaran yang kondusif. Temuan ini relevan untuk mengembangkan program pelatihan di masa depan dan merumuskan kebijakan pendidikan yang mempertimbangkan peran teknologi dalam meningkatkan aksesibilitas dan kualitas pendidikan.
PEMBERDAYAAN SISWA-SISWI SEKOLAH MENENGAH KEJURUAN NEGERI PERIKANAN DALAM PEMBENIHAN IKAN AIR TAWAR
Authors: Mukti Akhmad Taufiq , Muhamad Amin  , Putri Desi Wulan Sari  , Veryl Hasan  , Gunanti Mahasri  , Puguh Yugo Wijanarko  , Lia Oktavia Ika Putri  , Salman Aldo Alfaresi
Published: July 2024

The limited knowledge and skills in the hatchery technology application of the freshwater fish to seed production business are obstacles faced by prospective young entrepreneurs in the aquaculture sector. The Community Partnership Program (PKM) was provided as a strategic step to overcome the obstacles faced by the target partner group in this PKM activity in line with the Public Vocational Secondary School's (SMKN) expectations to provide sufficient insight into science and technology for SMKN students as provision for independent entrepreneurship. The aim of this PKM was to transfer the application of freshwater fish (catfish) hatchery technology and the produce fish seeds independently. The activity method was conducted through: a) delivery of material and training related to broodstocks selection and gonad maturation, b) training on the application of freshwater fish hatchery technology (catfish), and c) regular monitoring and assistance to PKM target partner groups by involving related agencies (SMKN). Delivery of material was carried out regularly, both online and face to face (offline). Approximately 40 students of SMKN Ngadirojo, Pacitan Regency who took the flagship program of Aquaculture Agribusiness, attended this activity. This PKM activity was also attended by accompanying teachers. The practical results show an increase in the knowledge and skills of partners in catfish hatchery through the application of semi-artificial catfish broodstocks spawning technology.