bluuebunny/crossref_metadata_2025 huggingface dataset:
The new design of cows' behavior classifier based on acceleration data and proposed feature set
Authors: Phi Khanh Phung Cong ,   VNU University of Engineering and Technology, 144 Xuan Thuy, Hanoi City, Vietnam, Tran Duc-Tan , Duong Van Tu , Thinh Nguyen Hong , Tran Duc-Nghia ,   Faculty of Electrical and Electronic Engineering, Phenikaa University, Hanoi City, Vietnam,   NTT Hi-Tech Institute–Nguyen Tat Thanh University, 300A Nguyen Tat Thanh Street, Ward 13, District 4, Ho Chi Minh City, Viet Nam,   Institute of Information Technology, Vietnam Academy of Science and Technology, Hanoi City, Vietnam
Published: April 2020

Monitor and classify behavioral activities in cows is a helpful support solution for livestock based on the analysis of data from sensors attached to the animal. Accelerometers are particularly suited for monitoring cow behaviors due to small size, lightweight and high accuracy. Nevertheless, the interpretation of the data collected by such sensors when characterizing the type of behaviors still brings major challenges to developers, related to activity complexity (i.e., certain behaviors contain similar gestures). This paper presents a new design of cows' behavior classifier based on acceleration data and proposed feature set. Analysis of cow acceleration data is used to extract features for classification using machine learning algorithms. We found that with 5 features (mean, standard deviation, root mean square, median, range) and 16-second window of data (1 sample/second), classification of seven cow behaviors (including feeding, lying, standing, lying down, standing up, normal walking, active walking) achieved the overall highest performance. We validated the results with acceleration data from a public source. Performance of our proposed classifier was evaluated and compared to existing ones in terms of the sensitivity, the accuracy, the positive predictive value, and the negative predictive value.
Le site de Kınık-Höyük et la Cappadoce méridionale : recherches archéologiques et historiques
Authors: Balza Maria Elena
Published: April 2020

Since 2007 a team of researchers from the University of Pavia began a series of archaeological research, historical and epigraphic in Niğde region of southern Cappadocia. This research led in 2011 to the opening of genuine archaeological excavations on the site of Kınık Höyük, one of the most interesting settlement of the region due to its geographic location and its dimensions. In this short contribution we propose on the one hand, to present the results of the first two excavation campaigns on the site and on the other hand, to expose historical research underway in the region. Since ancient times, Southern Cappadocia has indeed played a key role as a contact and exchange zone between different inputs, from the heart of Anatolia to the north, to the Levant the south and Assyria in in the east.
Quelques nouvelles données sur la chronologie des phases anciennes de Porsuk, du Bronze Moyen à la réoccupation du Fer
Authors: Beyer Dominique
Published: April 2020

In recent years, various surveys made on the ground, supported by dendrochronology or radiocarbon, helped correct or refine historical data concerning the foundation destructions and reconstructions phases of the city of Porsuk, identified as the ancient Tunna or Dunna according to Hittite and Assyrian sources. If there are still many questions, it is clear that the occupation phase of the Old Hittite Kingdom is much more important than previously thought. The evaluation of the gap between the end of the Bronze Age and the Iron Age remains delicate to assess precisely.
Porsuk – Zeyve höyük à l’Âge du Fer : le cas des fibules comme marqueurs d’échanges et de datation
Authors: Patrier-Lacambre Julie
Published: April 2020

Fibulae are important historical and cultural markers for the Iron Age. Since the first excavations at Porsuk in 1969 until the 2011 campaign, fourteen fibulae have been discovered on the site. The study of these objects, still unpublished, aims at providing a contribution to the assessment of the links that could have been existed, in the region of Porsuk and Tyanitide, between Phrygians and Neo-Hittites.
Réflexions sur les relations entre la Cappadoce méridionale et la Cilicie : les deux Kastabala et Artémis Pérasia
Authors: Casabonne Olivier
Published: April 2020

Like the two Komana, Pontus and Cappadocia, there were two Kasbala, one in Cilicia and the other in southern Cappadocia. This duplication allows us to understand the geopolitical relations between the two regions and the importance of the Tyanitide/Tyanide in the transmission of cultural facts from the East to the West.
Toulouse/Tolosa, cité des Tolosates et Auch/Elimberris, cité des Ausques : des centres de pouvoir indigènes aux capitales romaines
Authors: Gardes Philippe
Published: April 2020

Les recherches archéologiques récentes permettent de s’interroger sur les conditions d’apparition de deux capitales de cités du sud-ouest de la Gaule : Toulouse et Auch. Ces villes succèdent à un centre de pouvoir indigène qui, dans les deux cas, est abandonné après avoir emprunté la voie d’une certaine forme d’acculturation urbaine après la Conquête. Cette dernière prend la forme d’une mutation de l’architecture et des formes d’habitat. Ainsi, on observe non seulement l’adoption de techniques de constructions italiques mais aussi de modèles architecturaux et esthétiques. La situation change au tournant de l’ère avec la création de capitales, dont le programme urbanistique répond aux nouvelles exigences juridiques et administratives issues des réformes augustéennes.
Saintes/Mediolanum, cité des Santons et Bordeaux/Burdigala, cité des Bituriges Vivisques : destins croisés
Authors: Maurin Louis , Bouet Alain , Hiriart Eneko , Landreau Guilhem , Sireix Christophe , Tardy Dominique
Published: April 2020

En raison de leurs « destins croisés », une seule étude réunit Saintes/Mediolanum et Bordeaux/Burdigala pour présenter leur passage sous la domination romaine. Depuis un quart de siècle, les recherches archéologiques et numismatiques ont permis de croire qu’au moment où éclata la guerre des Gaules, leur histoire était liée, ce qu’ont paru confirmer certaines interprétations des silences de César dans les causes du conflit qui l’opposa aux Helvètes. Divers indices ont conduit à avancer qu’à l’époque les Santons ambitionnaient d’exercer leur mainmise sur Bordeaux, considéré comme le débouché de l’isthme gaulois, mais ils sont encore fragiles. Les recherches archéologiques récentes montrent que les deux villes avaient des origines bien différentes : Bordeaux apparaît depuis 600 av. J.-C. environ comme un comptoir commercial sur la rive gauche de la Gironde ; Mediolanum est peut-être née, et dès avant la guerre, du déplacement sur la rive gauche de la Charente de l’oppidum des Santons, sans doute situé jusqu’alors à Pons. Ce peuple figure parmi les grands vaincus de la conquête césarienne : l’étendue de son territoire aurait été amoindrie vers le sud et – ce qui peut être tenu pour très vraisemblable – les Romains constituèrent de ce côté une puissance nouvelle, celle des Bituriges Vivisques déracinés du Berry et déplacés sur l’estuaire ; le petit emporium de Bordeaux fut leur capitale. Auguste constitua en cité les Bituriges Vivisques comme les Santons, et leurs chefs-lieux furent ornés d’un sanctuaire du culte impérial. Les institutions politiques y sont semblables ; les inscriptions montrent que, marquées pour la forme d’un cachet gaulois, elles assurent le pouvoir de l’ancienne classe dominante ralliée à Rome.Dans la génération qui suit la guerre, Mediolanum et Burdigala connaissent un brusque développement sous des aspects voisins. Les deux villes s’épanouissent à l’époque augustéenne, et leur essor est parallèle dans la première moitié du ier s. apr. J.-C. pour ce que nous en savons, avant tout dans l’établissement d’un plan d’urbanisme et la construction d’équipements pour le confort et la salubrité (aqueducs, fontaines) ; cela n’a rien d’original dans la Gaule romaine. L’empreinte culturelle de l’époque de l’Indépendance est nettement plus prononcée à Saintes, alors que cette ville jouit, des deux dernières décennies avant notre ère jusqu’au milieu du ier s., d’une importante parure architecturale proprement romaine qui lui donne un éclat incomparable par rapport à sa voisine et aux autres cités de la nouvelle province d’Aquitaine.
Rennes/Condate, cité des Riédons : aux origines d’une ville-capitale
Authors: Le Cloirec Gaétan , Pouille Dominique , Labaune-Jean Françoise , Besombes Paul-André , Jean Stéphane , Lorho Thierry
Published: April 2020

Plusieurs fouilles importantes ont eu lieu à Rennes depuis la fin des années 1980. Bien qu’elles aient toutes concerné la moitié nord du chef-lieu des Riédons, les informations qu’elles ont fournies ont profondément renouvelé la vision de l’organisation urbaine entre le i er et le iv e s. apr. J.-C. Entre 2012 et 2014, les opérations archéologiques réalisées dans le couvent des Jacobins et sur la place Sainte-Anne ont encore apporté des éléments essentiels sur les modalités de fondation de Condate sous le règne d’Auguste. Elles confirment surtout que le cœur de la cité se trouve dans ce secteur précis où se concentrent à la fois les plus anciennes occupations et la plus forte densité de vestiges archéologiques. La découverte d’un imposant édifice public et la présence d’un monument de carrefour illustrent l’importance de ce secteur dès l’origine. Il n’échappera pourtant pas à un déclin momentané qui semble frapper l’ensemble de l’agglomération au début du i er s. Après cet épisode, bien avéré mais encore difficile à comprendre, la reprise en main qui s’opère sous Claude transparaît à travers l’aménagement des espaces publics de circulation et la construction de nouveaux bâtiments. Les fouilles traduisent alors le rôle essentiel des artisans, métallurgistes et céramistes notamment, dans l’installation durable de l’urbanisme, mais plusieurs indices posent aussi la question d’une implication des militaires sans qu’on puisse en évaluer le rôle précis et l’importance.
Amiens/Samarobriva, cité des Ambiens : aux origines de la ville romaine
Authors: Bayard Didier
Published: April 2020

La question des origines et des débuts de la ville romaine de Samarobriva été abordée à plusieurs reprises dans les dernières décennies. Le scénario d’ensemble a été défini en 1983. Il présente deux paradoxes. Le premier concerne ses origines : en dépit de la mention de son nom à consonance celtique dans les commentaires de La Guerre des Gaules ou dans la correspondance de Cicéron, aucun lien matériel n’a pu être établi entre la ville romaine et un antécédent gaulois, ni même avec un camp césarien.Il semble bien que ce soit la construction de la voie de l’Océan, peut-être lors du second gouvernement d’Agrippa en Gaule, entre 19 et 16 av. J.-C., qui est à l’origine d’une agglomération au bord de la Somme. La voie a été retrouvée extrêmement bien conservée dans le fond de la vallée. Cette agglomération prend l’aspect d’une ville organisée selon un vaste quadrillage de rues régulier entre la fin du règne d’Auguste et le milieu du ier s. apr. J.-C. L’analyse du plan général montre que ce quadrillage répond à un schéma directeur cohérent, accréditant l’hypothèse d’un acte de fondation initial. La question principale qui se pose aujourd’hui est la datation de cette fondation. Si la mise en place des chaussées de gravier et silex est datée partout, à l’exception de deux voies du centre de la ville, des années 50 qui correspondent effectivement à un moment décisif dans l’histoire de la ville, divers indices suggèrent l’existence d’une agglomération déjà fort étendue à la fin du règne d’Auguste avec des habitats organisés selon ce même schéma directeur. Nous verrons de quelle façon et dans quelle mesure il est possible à partir de la documentation disponible de surmonter ces difficultés.
Sens/Agedincum, cité des Sénons
Authors: Nouvel Pierre , Delor-Ahü Anne , Estur Émilien , Venault Stéphane
Published: April 2020

La multiplication des opérations préventives et la reprise des données anciennes permettent aujourd’hui de reconsidérer la question de l’origine de la capitale des Sénons. L’Agedincum romaine est précédée d’une agglomération ouverte, remontant au iie s. voire au iiie s. av. J.-C., installée au confluent de l’Yonne et de la Vanne et mentionnée par César. Vraisemblablement avant 3 av. J.-C., une nouvelle trame urbaine est implantée à un kilomètre au nord-est, profitant ici du percement de la voie dite de l’Océan signalée par Strabon. Son quadrillage régulier, déterminé par le tracé de cette voie, couvre environ 110 ha. Cependant, les vestiges datables des premières décennies de la ville sont bien peu nombreux, même si l’on peut supposer que certains des monuments attestés à une période plus tardive (forum, thermes, sanctuaire périurbain de la Motte du Ciar) existaient déjà. La rareté des documents épigraphiques et des éléments archéologiques en contexte ne permet pas d’étudier avec précision la structure de la population et la nature des activités qui s’y déroulaient. Il semble néanmoins que son développement initial soit assez lent : il faut attendre le iie s. apr. J.-C., voire le début du iiie s. apr. J.-C. pour qu’Agedincum atteigne son plein essor.
Le cens, l’autel et la ville chef-lieu : Auguste et l’urbanisation des Trois Gaules
Authors: Van Andringa William
Published: April 2020

Cet article propose de retracer et comprendre le processus fondamental d’urbanisation des Trois Gaules – il marque l’avènement de la civilisation municipale dans ces régions – en reprenant la documentation textuelle disponible à la lumière des résultats de l’archéologie urbaine récente. En Gaule intérieure, le démarrage fondamental intervient bien au lendemain de la guerre des Alpes et dans le contexte de la préparation de la conquête de la Germanie, très exactement entre 15 et 12 av. J.-C. C’est à ce moment-là qu’Auguste établit un sénat, des magistrats et des lois dans les cités de la Gaule Chevelue. Les négociations se sont poursuivies après son départ, notamment lors des réunions régulières organisées à l’autel du confluent et dans le cadre des recensements supervisés par Drusus en 12 av. J.-C., puis par Germanicus en 14 apr. J.-C. L’intervention de l’État romain, lors de l’écrasement de la révolte de 21 et après, a dû également jouer dans l’accélération des programmes urbains, dans les rythmes de développement des chefs-lieux.
Text Mining Business Policy Documents
Authors: Spruit Marco , Ferati Drilon
Published: April 2020

In a time when the employment of natural language processing techniques in domains such as biomedicine, national security, finance, and law is flourishing, this study takes a deep look at its application in policy documents. Besides providing an overview of the current state of the literature that treats these concepts, the authors implement a set of natural language processing techniques on internal bank policies. The implementation of these techniques, together with the results that derive from the experiments and expert evaluation, introduce a meta-algorithmic modelling framework for processing internal business policies. This framework relies on three natural language processing techniques, namely information extraction, automatic summarization, and automatic keyword extraction. For the reference extraction and keyword extraction tasks, the authors calculated precision, recall, and F-scores. For the former, the researchers obtained 0.99, 0.84, and 0.89; for the latter, this research obtained 0.79, 0.87, and 0.83, respectively. Finally, the summary extraction approach was positively evaluated using a qualitative assessment.
"It was competitive, it was very competitive!": memory of school sports of performance in particular schools of Curitiba (1980-1990)
Authors: Vargas Pauline Iglesias , Capraro André Mendes
Published: April 2020

The present study investigated the practice of school-based sport in private schools in Curitiba-PR, between 1980 and 1990, by means of interviews with technicians, athletes and sports managers who experienced the phenomenon during this period were interviewed. The research is qualitative in nature and the research method used was true Oral History. From the analysis it was noticed that a good part of the schools of Curitiba of the time maintained sports teams of income; the context of the Curitiba school sport was a kind of metaphor of professional sport; there was a hegemony of collective sports; the feminine sport sedimented in the memory of the interviewees was gymnastics; the teams were highly valued within the colleges; school teams participated in national and international championships; despite the character of income, there was already a difference of the sport practiced in clubs; some educational institutions were partnering with sports clubs.
Teaching self-efficacy and factors associated with the teaching practice of physical education faculty
Authors: Salles William das Neves , Folle Alexandra , Farias Gelcemar Oliveira , Nascimento Juarez Vieira do
Published: April 2020

Teaching self-efficacy (SE) refers to the belief that teachers/professors have in their own ability to exert a relevant effect on their students' engagement and learning, which is an important indicative of their pedagogical behavior. This associative, predictive empirical study aimed to investigate teaching self-efficacy profiles and the factors associated with the teaching practice of Physical Education (PE) faculty. The College Teaching Self-Efficacy Scale was applied to 43 professors from a Brazilian public university, and data were analyzed by descriptive statistics, the Chi-Squared test, and Binary Logistic Regression (α=5%) on SPSS 25 software. Results revealed high teaching SE levels, both in the general scope and in the specific dimensions of professional practice (teaching planning, student engagement, in-class interaction promotion, learning assessment and self-assessment), besides evidencing strong associations between teaching SE dimensions. SE for teaching planning explained 34.40% of the variation in the professors' behavior, which indicates a need to carry out new investigations with a more in-depth analysis of the influence exerted by other personal, professional and contextual factors on the perceptions of teaching SE within the PE university context.
Knowledge production on sport economics: a systematic review
Authors: Reis Nadson Santana , Húngaro Vitor , Magalhâes Ywry Crystiano da Silva , Mascarenhas Fernando
Published: April 2020

The study analyzes the scientific production that deals with the economic activity of the sport. This is a systematic review that evaluates scientific papers published in the last Olympic cycle (2012-2016) in national and international journals, in English, Spanish and Portuguese, indexed to the Portal of Journals of Capes (Coordination for the Improvement of Higher Education Personnel). From the content analysis, 355 studies were examined that, despite their diversity, were grouped into 16 categories. The considerations suggest an ample process of commercialization of the sport as a cultural commodity and, also, vehicle of sale and propagation of other products.
ANÁLISE NÃO LINEAR DE TRELIÇAS COM A FORMULAÇÃO CORROTACIONAL DE ELEMENTOS FINITOS E DIFERENTES MEDIDAS DE DEFORMAÇÕES
Authors: João Pedro de Lima Miyazaki  , Souza Luiz Antonio Farani de , Carlos Humberto Martins
Published: April 2020

Treliças quando submetidas a grandes carregamentos em seus nós apresentam não linearidade geométrica, que ocorre quando a relação entre deslocamento e deformação não são mais lineares. A formulação corrotacional de Elementos Finitos para solução do problema não linear geralmente é feita utilizando a deformação de engenharia. No entanto, existem outras medidas de deformação que podem ser utilizadas na formulação e levar a diferentes resultados, destacando-se as deformações de Green-Lagrange, Biot e Almansi. Este artigo apresenta um modelo numérico-computacional para análise de treliças com não linearidade geométrica. As trajetórias de equilíbrio de problemas de treliças planas são obtidas para as diferentes medidas de deformação, e os resultados numéricos são comparados. O sistema de equações não lineares foi solucionado pelo procedimento incremental e iterativo de Newton-Raphson padrão associado à técnica de continuação Comprimento de Arco Linear. O código computacional foi implementado no software Scilab.
Earth Abundant Metals as Cost Effective Alternatives in Photocatalytic Applications: A Review
Authors: Nkabiti L. Legapa , Baker Priscilla Gloria Lorraine
Published: April 2020

In a quest for a cleaner planet and to have alternative forms of energy generation apart from the fossil-based power supply, fuel cell technology has emerged as an alternative energy source for usage across all economic sectors. The application of this age-old technology is found in alkaline (AFC), molten carbonate (MCFC), phosphoric acid (PAFC), polymer electrolyte membrane (PEMFC) and solid oxide (SOFC) fuel cells. These fuel cells are named based on the type of electrolyte employed in their applications and the fuel of choice for energy generation is hydrogen. This fuel can be used in its pure form or extracted from other sources such as methanol, water and syngas. Ammonia in its liquefied and gaseous forms may be used as a non-carbonaceous fuel for the hydrogen source in some of these fuel cell technologies due to its safety, lower price, ease of storage and transportation. In this review, all the fuel cells will be investigated in their capability of using ammonia as a direct fuel. The role of earth abundant metal catalysts in comparison to TiO2 was evaluated in terms of molecular orbital theory and in the decomposition of organic compounds and other material into nitrogen and hydrogen products under the visible light radiation. The p-orbital participation in earth abundant metals or metal oxides doping, emerged as a strong contribution to bandgap attenuation.
Study of α”-Martensitic Transformation in Ti35NbxSn Alloys Subjected to Cryogenic Heat Treatment
Authors: Silva Abraão , Azevedo Thiago Figueiredo , Sampaio Weslley Rick Viana , Pereira Luiz Carlos , Griza Sandro
Published: April 2020

TiNbSn alloys have been extensively researched due to several properties they exhibit, including high mechanical strength, low elastic modulus, superelasticity, shape memory effect, biocompatibility. The present study evaluated the cryogenic heat treatment in the Ti35NbxSn alloys (x = 0.0; 2.5; 5.0; 7.5). The alloys were arc melted, cold formed and quenched in both water and liquid nitrogen at-198° C. The Ti35Nb2.5Sn alloy was also aged after exposed to both quenching medium. Microstructure and microhardness analyses were performed. Cryogenic treatment was not enough for transformation of primary β phase into martensitic α” in alloys containing 5 and 7.5% Sn. Cryogenic treatment provided β to α” transformation in alloys containing 0 and 2.5% Sn. The Sn-free alloy was more likely to α" transformation in both quenching medium. The alloys microhardness increased with decrease of both quenching temperature and Sn content. The increase of α" is also related to the increase of the alloy microhardness after aging.
Susceptibility Study to Hydrogen Embrittlement of Welded Joints of API 5L X52 Steel in Sulphide Media
Authors: Kohls Daniel , Gemelli Enori , Filho Laercio da Silva , Bernardo Majorie Anacleto
Published: April 2020

Pipelines for oil and gas, manufactured in high-strength low-alloy steels (HSLA), such API pipes, promote high levels of strength and fracture toughness. Therefore, it is important to ensure this high level of toughness in the welded joint. When the pipelines are exposed for many years to wet H2S environments, they can fail due to hydrogen embrittlement. Thus, it is important to evaluate the influence of different weld specifications in the susceptibility to hydrogen embrittlement. In this case, the aim of this work was to study the susceptibility to hydrogen embrittlement of API 5L X52 steel and in the welded region in wet environments. The welding was performed in the circumferential direction by GMAW process in two different specifications (with lower and higher thermal input). The susceptibility to hydrogen embrittlement was carried out according to NACE TM0177 and SSRT (slow strain rate tensile tests) test, performed according to ASTM G 129 standard. All welded joints and base metal did not show any signal of cracks and susceptibility to hydrogen embrittlement, according to the requirements of the NACE TM0177 test. According to SSRT tensile test, the results showed that the welded joints and base metal are susceptible to hydrogen embrittlement. The tensile tests exhibited a drop in the strain and necking, and higher values of yield stress. The welded joint with the lowest heat inputs employed in the welding process presented the highest susceptibility to hydrogen embrittlement.
Experimental Study of Tensile and Flexural Strength of Cottonseed Hull Reinforced Epoxy Composites
Authors: Cho Mingyu
Published: April 2020

In this study, the tensile and flexural strengths of cottonseed hull reinforced epoxy composites were investigated. Specimens were made using a stainless steel mold. A hand lay-up process was used to make the composite material, and three kinds of materials were made: unreinforced epoxy, raw cottonseed hull reinforced composite, and grinded cottonseed hull reinforced composite. The fiber content of all composites is 15 wt%. Tensile and flexural test were performed with universal testing machine. The result shown that Tensile and flexural strengths of grinded cottonseed hull reinforced composites were found to be the highest.
Recenti osservazioni di Acheta domesticus (L., 1758) (Orthoptera Gryllidae) in Piemonte (Italia nord occidentale)
Authors: Dutto Moreno , Ferracini Chiara , Drago Andrea , Martini Simone
Published: April 2020

Acheta domesticus (L., 1758) è una specie sinantropica e antropofila ritenuta localmente rara e in progressiva rarefazione a causa delle migliorate condizioni igieniche e costruttive delle abitazioni e per la competizione con Gryllomorpha dalmatina dalmatina (Ocskay, 1832). In base ai dati bibliografici, A. domesticus, fino al 2009, era nota solo per tre località piemontesi. A seguito di indagini negli ambienti urbani (abitazioni) la presenza della specie è stata accertata in altre nove località nelle province di Cuneo e Torino. L’assenza di dati è quindi probabilmente imputabile non tanto alla rarefazione della specie quanto invece a: a) riduzione progressiva dell’interesse applicato a partire dal secondo dopoguerra, b) scarso interesse collezionistico e c) difficoltà di accesso agli ambienti in cui è confinata (abitazioni private).
LYON-UNIVERSITY HOSPITAL EXPERIENCE WITH GEMTUZUMAB OZOGAMICIN THERAPY IN ACUTE MYELOID LEUKEMIA: A ‘REAL-LIFE’ STUDY
Authors: Thomas Xavier , Laurino Marica , Loron Sandrine , Larcher Marie-virginie , Fossard Gaëlle , Elhamri Mohamed , Deloire Alexandre , Balsat Marie , Barraco Fiorenza , Labussière Hélène , Ducastelle Sophie , Renault Myriam , Wattel Eric , Heiblig Maël , Salles Gilles
Published: April 2020

One-hundred and four adults with newly diagnosed or relapsed/refractory acute myeloid leukemia (AML) were treated with fractionated doses of gemtuzumab ozogamicin (GO) at one-single French center over a 10-year period. We attempted to define predictive factors for response and survival. The overall response rate was 70% (86% in newly diagnosed and 67% in relapsed/refractory AML). Disease-free survival (DFS) and overall survival at 3 years after GO treatment was 31% and 29%, respectively. Mortality during induction was 7%. Among remitters, allogeneic hematopoietic stem cell transplantation can be performed in 33 cases (45%). DFS at 3 years was 54%. Incidences of transplant-related mortality, grade ≥ 3 acute graft-versus-host (GvH) disease, and extensive chronic GvH disease were 15%, 12%, and 27%, respectively.No sinusoidal obstruction syndromes were reported among allografted patients as among the other patients in the studied cohort. GO-based chemotherapy is a viable option for treatment of newly diagnosed and relapsed/refractory AML patients, and is a feasible schedule as a bridge to allogeneic transplant.
CLINICAL USEFULNESS OF BROCHOALVEOLAR LAVAGE IN THE MANAGEMENT OF PULMONARY INFILTRATES IN ADULTS WITH HAEMATOLOGICAL MALIGNANCIES AND STEM CELL TRANSPLANTATION
Authors: Jorge Laura , Torres Diego , Languasco Agustín , Rodriguez Pablo , Bonvehí Pablo , Temporiti Elena , Relloso Silvia , Videla Cristina , Herrera Fabián
Published: April 2020

Introduction: Pulmonary complications are frequent in patients with hematologic malignancies and stem cell transplantation. Regardless of the microbiological usefulness of bronchoalveolar lavage (BAL), little information exists on both its benefits as a guide for therapeutic decisions and its impact on patients’ clinical outcome.

Methods: A prospective observational single center study was performed between July 2011 and July 2015. Consecutive episodes of pulmonary infiltrates were analyzed in subjects over 18 years of age who presented hematologic malignancies and underwent chemotherapy or stem cell transplantation.

Results: Ninety-six episodes of pulmonary infiltrates were analyzed. Acute leukemia was the most frequent underlying condition. Thirty-seven patients (38.5%) received a stem cell transplant. Sixty-one (62.9%) were neutropenic at the moment of inclusion in the study. A definitive etiologic diagnosis was obtained in 41 cases (42.7%), where infection accounted for the vast majority of causes (33 cases, 80.5%). Definitive diagnosis was reached by non-invasive methods in 13 cases (13.5%). BAL was performed in 47 cases, and led to a diagnosis in 40.4% of the cases. BAL results led to therapeutic changes in 27 cases (57.4%), including the addition of new antimicrobials to empiric treatments in 10. Regarding BAL’s safety, 2 patients experienced minor adverse events and 1 a severe adverse event; no procedure-related deaths were observed.

Conclusions: Infection was the leading cause of pulmonary infiltrates in patients with hematologic malignancies and stem cell transplantation. BAL was a useful decision-making diagnostic tool, with minor adverse events
SARS-CoV-2 (COVID-19) and Chronic Myeloid Leukemia (CML): a case report and review of ABL kinase involvement in viral infection
Authors: Abruzzese Elisabetta , Luciano Luigia , D'Agostino Francesco , Trawinska Malgorzata Monika , Pane Fabrizio , De Fabritiis Paolo
Published: April 2020

no abstract available
Aknowledgements:
We thank professor Nathan Tubliz, dept. Biology, University of Oregon, for his insightful support.
The response of animals to suxamethonium (succinyldicholine) and succinylmonocholine
Authors: Hattingh J. , Pitts N. I. , De Vos V. , Moyes D. G. , Ganhao M. F.
Published: April 2020

The time which elapses before cessation of breathing, and blood pressure and blood gas changes after the intramuscular administration of suxamethonium, or a mixture of suxamethonium and hexamethonium, is compared in immobilised African elephants (Loxodonta africana) and buffaloes (Syncerus caffer). In addition, the respiratory responses of elephants and other animals to intravenous administration of suxamethonium and succinylmonocholine are reported on, as are the effects of darting animals with succinylmonocholine. The results show that respiration is affected in a similar fashion in all species investigated. However, the characteristic gradual decrease in respiratory rate seen in elephants during culling, using suxamethonium, resembles the effects observed when succinylmonocholine is administered. It is suggested that elephants are killed by this first breakdown product of suxamethonium during culling and/or that unique acetylcholine receptors may be involved.
Micro-CT analysis of two-dimensional and three-dimensional parameters in severely curved roots prepared with 3 instrumentation systems: An in vitro study
Authors: Souza-Flamini Luis Eduardo , Crozeta Bruno Monguilhott , Silva Ricardo Gariba , Savioli Ricardo Novak , Sousa-Neto Manoel Damião , Cruz-Filho Antonio Miranda da
Published: April 2020

Aim: This study analyzed the two-dimensional (2D) and three-dimensional (3D) parameters and canal transportation using micro-CT in roots prepared with three instrumentation systems preceded or not by glide path. Materials and Methods: Sixty mesial canals of mandibular molars with severe curvature angles (≥25°) were divided randomly (n = 10): G1-Twisted-file-adaptive (TFA); G2-Reciproc (RC); G3-One-Shape (OS); G4-ProGlider (PG)+TFA; G5-PG+RC; and G6-PG+OS. Area, perimeter, circularity, and major and minor diameters at the apical 5 mm and volume and surface area and canal transportation were evaluated. Data were analyzed using two-way analysis and Tukey's test (α = 0.05). Results: RC showed significantly higher areas and lower perimeters and diameters than TFA (P < 0.001). Increases in root canal volumes promoted by RC and OS were similar (P = 0.979). There was no statistically significant difference in canal transportation (P = 0.083). RC generally promoted major changes in the 2D and 3D parameters. Conclusions: The RC system caused a significantly higher perimeter and area increase than the TFA system. The preceding use of PG in the instrumentation techniques did not influence the evaluated parameters.
In vitro evaluation of the erosive effect of probiotic drink on tooth enamel
Authors: Zulkapli Rahayu , Daslam Daslianah , Safiai Nur Fazlin Syahirah Mohamad , Zainal Mukarramah , Zain Nurhayati Mohamad
Published: April 2020

Purpose: The study aimed to evaluate the erosive activity of six probiotic drinks (PD) on tooth enamel. Methods: Forty-eight extracted human teeth premolar free of hypocalcification and carious were used in this study. The erosive activity was evaluated by measuring the pH, titratable acidity (TA), tooth weight loss, and the rate of calcium release after 5-min exposure daily over 7 days. Results: The pH of the PD was found to be in acidic range (3.08–4.10) with different TA values depending on the bacterial strain presence. The highest pH value showed minimum TA. The erosion was determined by the rate of calcium release and weight loss from the enamel surface on exposure to PD. Most of the samples showed consistent calcium reabsorption to the tooth enamel after 5 min of exposure daily over 7 days. However, all the samples showed persistent weight loss over 7 days' exposure. Conclusion: Although PD was found to be acidic, it exhibited low erosive activity, most probably due to the presence of high calcium content and certain bacterial strains in the drink. The number and type of bacterial strain in the drink did not significantly contribute to the erosion of the enamel, as no calcium loss was found except for certain drinks of repeated exposure in days 3 and 5. However, consistent weight loss was measured over a period of 7 days. In conclusion, PD does not cause any calcium loss on tooth enamel. Other than beneficial to the gut, it also promotes calcium reabsorption to the tooth enamel.
Абсолютная непрерывность спектра периодического оператора Шрeдингера в цилиндре с третьим краевым условием
Authors: Kachkovskii Il'ya , Filonov Nikolai Dmitrievich
Published: April 2020

Доказана абсолютная непрерывность спектра оператора Шрeдингера $H = - \Delta + V$ в гладком цилиндре с третьим краевым условием $\partial_\nu u = \sigma u$ на границе в предположении, что коэффициенты $V$ и $\sigma$ периодичны по продольным переменным.
Многосолитонные решения уравнения Дегаспериса-Прочези и его коротковолнового предела: подход преобразования Дарбу
Authors: Li Nianhua , Wang Gaihua , Kuang Yonghui
Published: April 2020

Предложен новый подход к нахождению многосолитонных решений уравнения Дегаспериса-Прочези и его коротковолнового предела, основанный на сочетании преобразования взаимности с преобразованием Дарбу для отрицательного потока иерархии Каупа-Купершмидта. В частности, показано, что различный выбор параметров солитонов приводит к двум различным типам солитонных решений для уравнения Дегаспериса-Прочези.
Is there scientific progress in macroeconomics? The case of the NAIRU*
Authors: Lang Dany , Setterfield Mark , Shikaki Ibrahim
Published: April 2020

We address the question posed in the title of this paper by investigating recent developments in the literature that estimates the NAIRU. A necessary condition for the existence of a NAIRU is dynamic homogeneity: the Phillips curve should be homogeneous of degree one in lagged and/or expected inflation. But contemporary approaches to estimating the NAIRU typically assume rather than test for dynamic homogeneity, thus assuming (rather than testing for) the existence of a NAIRU. We argue that these developments remove the NAIRU from the domain of testable hypotheses and transform the concept into an article of faith. This does not constitute scientific progress.
PENELITIAN TENTANG PENGGUNAAN LKS DALAM KEGIATAN CBSA BIDANG STUDI MATEMATIKA DI SMPN 1 DARUL KAMAL ACEH BESAR
Authors: Zuhratuddin
Published: April 2020

Berdasarkan hasil analisis data penelitian ini tidak ada perbedaan yang berarti antara hasil belajar kelompok belajar siswa yang belajar dengan menggunakan Lembaran Kerja Siswa (LKS) dengan hasil belajar kelompok siswa yang tidak menggunakan Lembaran Kerja Siswa (LKS). Tidak berbedanya hasil belajar di kedua kelompok menurut pengamatan peneliti disebabkan siswa kurang menjalankan perannya dengan baik terutama dalam mempersiapkan diri dalam menghadapi proses belajar mengajar yang berlangsung. Tetapi selama proses belajar mengajar berlangsung terlihat keaktifan siswa yang memakai LKS lebih tinggi dibandingkan dengan siswa yang tidak memakai LKS.
PENDEKATAN PEMBELAJARAN METODE BERMAIN PADA ASPEK FISIK DAN MOTORIK DI TAMAN KANAK-KANAK
Authors: Ahadin
Published: April 2020

Pendekatan pembelajaran atau strategi penbelajaran direncanakan dan dibuat untuk mencapai tujuan dari pembelajaran. Suatu strategi pembelajaran diterapkan agar tujuan pembelajaran dapat dicapai sebagaimana yang diharapkan. Strategi pembelajaran dapat dijabarkan menjadi dua bentuk yaitu motode atau teknik. Karakteristik metode bermain adalah anak dengan motivasi intrrinsik, aktif, terbuka, lentur, bebas, gembira, menyenangkan, produk spiritual, murni, alami, keputusan, berpura-pura, kebutuhan, dan spontan. Sedangkan karekteristik anak taman kanak-kanak adalah mereka ingin mengexpresikan kata hati mereka dalam aktivitas atau kegiatan bermain dengan bebas, aktif, dan spontan. Aspek fisik dan motorik adalah salah satu aspek yang diajarkan taman kanak-kanak, yang materi . dari keterkaitan atau hubungan antara pendekatan pembelajaran metode bermain, katakteristik anak tamn kanak-kanak. Maka dapat disimpulkan bahwa metode bermain tepat atau sesuai untuk digunakan oleh guru dan taman kanak-kanak untuk mengajarkan aspek fisik dan motorik, agar tujuan pembelajaran dapat tercapai dengan baik.
MANAJEMEN KEPEMIMPINAN KEPALA MADRASAH DALAM MOTIVASI KERJA
Authors: Musdiani
Published: April 2020

Kepemimpinan merupakan suatu persoalan yang sangat aktual untuk dibicarakan, Karena dengan kepemimpinan dapat mempengaruhi orang lain untuk mengikuti tujuan yang diinginkan. Kunci keberhasilan suatu madrasah sesungguhnya terletak pada efesiensi dan efektivitas penampilan seorang kepala madrasah dan guru dalam melaksanakan tugas. Gaya kepemimpinan yang diterapkan kepala madrasah tersebut sangat berimplikasi terhadap motivasi guru dalam melaksanakan tugas. bahwa gaya kepemimpinan yang di terapkan kepala madrasah dalam peningkatan motivasi kerja adalah gaya transaksional, transformasional dan visionari, adapun gaya yang dominan di terapkan adalah gaya transformasional, sedangkan upaya kepala madrasah untuk peningkatan motivasi kerja telah diusahakan semaksimal mungkin dengan harapan guru bisa melaksanakan tugas sesuai dengan harapan, tujuan, dan sasaran yang diinginkan.
ANALISIS BUKU TATA BAHASA BETTY SCHRAMPFER AZAR FUNDAMENTALS OF ENGLISH GRAMMAR SEBAGAI BUKU TEKS UNTUK SISWA
Authors: Mulyadi
Published: April 2020

Riset ini adalah tentang analisa buku tatabahasa Betty Schramfer Azar Fundamentals English Grammar sebagai buku teks siswa. Tujuan reset ini adalah mengidentifikasikan langkah mengajar, materi ajar, ketrampilan bahasa dan unsur - unsur bahasa yang ada dalam buku tatabahasa ini. Sampel dalam reset ini adalah semua isi yang ada dalam buku tatabahasa Betty Schrampfer Azar. Penulis menyeleksi latihan-latihan tertentu dalam studi ini. Sementara itu ruanglingkup dalam studi ini menyangkut dengan ketrampilan bahasa dan unsur-unsur bahasa. Analisa data menunjukkan bahwa buku ini menekankan latihan-latihan tulisan. pada setiap unit. Tensis disini memeliki suatu peranan penting dalam menggunakan tatabahasa kedalam ungkapan-ungkapan lain. Sementara latihan lisan didalam buku ini untuk melatih siswa mampu merespon pertanyaan –pertanyaan temannya secara otomatis. Tingkat kesulitan keterampilan bahasa dan unsur bahasa dalam buku ini berbeda –beda. Demikian pulacontoh dan penjelasan dalam buku ini kalimat-kalimat yang disajikan dalam kalimat yang libih panjang dan latihan yang libih sulit. Kadang-kadang siswa harus mengembangkan kata-kata sendiri. Cek lis dalam kosa kata terdiri dari frasa dan klausa. Hasil dari riset ini menunjukkan bahwa siswa harus mampu tatabahasa dalam melatih keterampilan bahasa. Berdasarkan data yang telah dianalisa oleh penulis, ditemukan bahwa struktur bahasa yang difokuskan didalam buku ini. Maksudnya bahwa sebelum melatih keterampilan bahasa dan unsure bahasa, siswa disuruh untuk memahami struktur sebaik mungkin untuk dapat mengisi dan melatih latihan dengan benar.
PELAKSANAAN MANAJEMEN BERBASIS SEKOLAH DALAM MENINGKATKAN KUALITAS SISWA DI SEKOLAH
Authors: M. Husin
Published: April 2020

Secara garis besar kualitas pendidikan di Indonesia masih sangat memprihatikan. Oleh karena itu pemerintah melakukan reformasi pendidikan yang pada dasarnya sudah meupakan suatu tekat dan gerakan bangsa Indonesia yang selalu ingin melakukan perbaikan dalam kualitas sumber daya manusia Indonesia.Salah satu dalam bidang menajemen pendidikan. Manajemen berbasis sekolah (MBS) merupakan salah satu cara untuk meningkatkan kualitas pendidikan dan sumber daya manusia. Pelaksanan manajemen operasional berbasis sekolah dapat mempengaruhi peningkatan kulaitas pendidikan dan sumber daya manusianya disini terlihat peningkatan mutu kelulusannya.
PENERAPAN INDUKSI MATEMATIKA DALAM PEMBUKTIAN MATEMATIKA
Authors: Miksalmina
Published: April 2020

Induksi matematika merupakan sebuah teknik pembuktian pernyataan yang berkaitan dengan objek diskrit yang sangat penting. Penerapan induksi matematika di dalam matematika yang menjadi pokok bahasan utama untuk menjabarkan bagaimana induksi matematika dapat membuktikan sebuah masalah matematika. Induksi matematika merupakan metoda pembuktian yang dapat pula digunakan dalam pembuktian kebenaran algoritma. Induksi matematika memiliki tiga tahapan pembuktian. Tahap pertama, ialah langkah basis dimana tahapan ini untuk membuktikan bila p(n), n = 1 benar. Tahap kedua, merupakan tahap langkah induksi, tahapan yang membuktikan bila p(n) benar maka p(n+1) benar. Tahapan terakhir ialah konklusi, yang menyatakan bahwa semua p(n) adalah benar bila kedua tahapan sebelumnya benar. Pembuktian matematika membahas tentang strategi pembuktian. Bukti langsung, bukti tak langsung, dan bukti kontradiksi. Proses yang digunakan dalam melakukan proses pembuktian ialah proses majumundur, yaitu proses yang memerlukan titik awal. Penerapan induksi matematika dalam pembuktian sebuah masalah matematika memiliki empat prinsip induksi. Pertama; induksi matematika sederhana, sebuah pembuktian dengan metode bukti langsung; induksi matematika yang dirampatkan; induksi kuat dan induksi umum matematika. Induksi matematika sebuah metoda pembuktian matematika yang valid.
THE ABILITY OF STUDENTS IN USING ENGLISH CONJUNCTION (CASE STUDY AT SENIOR HIGH SCHOOL SMA NEGERI 5 BANDA ACEH)
Authors: Maulizan ZA
Published: April 2020

This research is about the ability of Students in Using EnglishConjunction. The aim of this study is to measure the ability of second year students ofSenior high school in using English conjunctions. The samples of this research were57 second semester students of senior high school. The determination of the sampleswas done randomly. In collecting the data, they were given a set of test inunderstanding the usage of conjunction. The number of items are 40, they weredivided into two parts, the first part (completed the paragraph in using coordinatingand subordinating conjunction) and the second part (complete the sentence in usingcoordinating and subordinating conjunction). In processing data the writer used thestatistical procedure such as, the range score, the interval width, the interval class, thefrequency distribution, and arithmetic mean ( X ). From the data analysis the meanscore of second semester students of senior high school is 60,15. It is considered thecriteria of value in this research is not enough. It is recommended to the researchwhich relates to the ability of second semester students of senior high school in usingconjunctions or other the same level can be continued by other researchers so that theunbreakable problems can be solved in the future.
MINIMIZING TRADITIONAL APPROACH IN INDONESIAN EDUCATION
Authors: Musdiani
Published: April 2020

This essay discusses the traditional approach in Indonesian education from different angle; cause and effect perspective. A traditional teaching approach employs a didactic flow of knowledge from the teacher, as a sage, to the student as a receptacle (Richmond, 2007) which more emphasizes the mastery of concept, with less stress on skills improvement. The common system of traditional education is teacher centred where the teacher focuses on delivering information about some contents (Liang, 2004). Teacher-centred class instruction and rote learning are deeply embedded; this type of instruction has become a part in the Indonesian school culture and unofficial standard of practice for years (USAID 2008; Bjork 2005). Shallow level of meaning found in school science (Aikenhead 2000). There are several explanations related to these problem; the institutional culture, the Indonesian school cultures; standardized and highly centralized examinations, and less emphasize on improving their teaching ability. Due to these causes, this paper proposes 4 solutions as follows; first, detaching the teachers from their dependence on and deference to the policies and regulations of the central government’s education authorities, Second, finding other methods of teacher recruitment, third, empowering the teachers: enriching pedagogical knowledge-lesson study/action research, and prosperity, last, providing a fair system which is emphasized on teaching Standard for standardized test.
PENGUASAAN SISWA PADA MATERI TRIGONOMETRI DI MAN DARUSSALAM ACEH BESAR
Authors: Miksalmina
Published: April 2020

Trigonometri merupakan materi pokok yang banyak menggunakan konsep yang akan terus berkembang dan bukan materi hafalan sehingga apabila siswa belum menguasai konsep materi sebelumnya maka dikhawatirkan akan mengalami kesulitan dalam materi selanjutnya. Namun kenyataan menunjukkan bahwa siswa sekolah menengah atas, pada umumnya masih banyak yang belum memahami dan mengalami kesalahan dalam mempelajari trigonometri serta belum mampu menguasai konsep-konsep trigonometri. Mengingat kenyataan tersebut, penulis melakukan penelitian terhadap siswa kelas XI IPA MAN Darussalam Aceh Besar dan bertujuan untuk mendeskripsikan tingkat penguasaan siswa terhadap materi trigonometri, menentukan jenis kesalahan dan penyebab kesalahan siswa dalam memahami materi trigonometri. Pendekatan yang digunakan adalah gabungan pendekatan kuantitatif dan kualitatif. Teknik pengumpulan data dilakukan dengan cara melakukan tes dan wawancara. Analisis data dilakukan dengan memeriksa jawaban siswa dan dikonversikan ke dalam kriteria penguasaan yang telah ditetapkan. Dari hasil pengolahan data diperoleh informasi bahwa dari 31 orang siswa yang mengikuti tes penguasaan materi trigonometri dapat disimpulkan bahwa yang menguasai kategori penguasaan-1 ada 11 orang (35,48%), yang menguasai kategori pengusaan-2 ada 4 orang (12,9%), dan kategori penguasaan-3 tidak ada satu orang pun yang menguasai (0%).