bluuebunny/crossref_metadata_2025 huggingface dataset:
Effectiveness of Structured Exercise Protocol on Muscle Imbalance of Quadriceps and Hamstrings in Postmenopausal Obese Women
Authors: Aphale Sawani Rajendra , Patil Chandrakant
Published: December 2023

Background and Objectives: In a woman who experienced menopause, there is a decrease in the strength of the muscle due to hormonal changes and because of several changes related to the hormones that occur in the body, it affects the body’s BMI which then affects to daily life. Physiotherapy is an effective way of reducing the majority of difficulties while doing daily activities and thereby improving overall health. The study aims to determine how the structured exercise protocol affects a muscle imbalance of hamstrings and quadriceps in postmenopausal obese women. Methodology: This research study was carried out on 50 females who experienced menopause and were between the age group 50-60 years the inclusion criteria were satisfied by them and they were divided into 2 groups randomly. Pre-interventional and post-interventional measurements were taken by Modified Sphygmomanometer, by 90-90 SLR test, Range of knee joints by goniometer also pain was assessed. Group A (the Control group) received the treatment which included hot moist therapy along with hamstrings active stretching, isometric exercises for both hamstrings and quadriceps and quadriceps strengthening and Group B received the treatment which included mulligans technique for hamstrings and for quadriceps muscle, MET technique was used. Both groups received the treatment for 6 weeks. Results: Statistically significant changes (with p-value <0.05) were seen in the pre and post-interventional measurements. But the value of the mean shows more progress in group B compared to group A. Research Conclusion: Both protocols are useful in the treatment of muscle imbalance in quadriceps and hamstrings in postmenopausal obese women but the Structured exercise protocol is more effective than the conventional protocol for muscle imbalance of quadriceps and hamstrings in postmenopausal obese women.
A Study on Various Dimensions of Quality of Work Life of Employees in Textile Industries with Special Reference to Tiruppur District
Authors: Muthuraju P.
Published: December 2023

Quality of Work Life (QWL) methods entail acquiring, developing, training, evaluating, and motivating people to attain the best outcomes possible by the organization’s goals. The current study has an impact on the dimension composed of Core components in terms of sustaining and developing QWL. The QWL refers to a workplace’s favorable circumstances and surroundings that provide and foster employees by offering benefits, job security, and opportunities for advancement. A total of 500 samples were gathered using a structured questionnaire and a convenience sampling method. The Spearman correlation test was used to look at the relationship between social relevance and social integration. The QWL in dimensions, according to the findings, comprises an examination of the correlation coefficient between social integration and social relevance.
Social Media and Working Memory - A Review
Authors: Dikshit Rishi , Kiran U. V.
Published: December 2023

Social media is a part of daily today life which is growing more and more widespread. Many individuals have mobile phones and often use social media. This review paper explores the impact of social media on working memory, a critical cognitive function. It discusses the widespread use of social media, its emotional influence, and its potential effects on cognitive processes. It highlights factors contributing to this complex relationship, including the type of engagement and platform design. Research indicates that using social media expands the possibility of becoming addicted. Excessive social media usage affects emotional well-being by strengthening negative feelings such as fear of missing out, melancholy, increased loneliness, anger, irritation, and anxiety. According to earlier research, the subject of whether using social media negatively affects our working memory has been raised. They cause numerous issues in our daily lives while they do the task. This literature review’s data came from a comprehensive database search of relevant previously published articles. A total of 25 papers were extracted from databases of which 10 were found relevant and hence chosen to be part of this review. The review revealed that online social media has a high potential to affect the cognitive functioning ‘working memory’ of people who spend their time on online social media platforms. The paper proposes interventions such as cognitive training, mindfulness practices, and digital detox programs to counter potential negative effects. Overall, it emphasizes the need for ongoing interdisciplinary research to better understand and address the interaction between social media and cognitive functions.
Assessment of Respiratory Morbidities among Shopkeepers and Vendors in a Semi-Urban Area
Authors: Keny J. Greeshma , Pandey Aastha Narayan
Published: December 2023

Context: Rapid urbanization has increased risk factors for respiratory morbidities, leaving the general population vulnerable. Potentially damaging agents are numerous, which result in damage to defence mechanisms, in turn causing respiratory morbidities. Shopkeepers and vendors in the semi-urban area, who mostly work outdoors at ground level, are continuously exposed to unhealthy environments and practices, and the majority are unaware of the situation. Aim: Our study will help identify the prevalence of respiratory morbidities and their association with risk factors. Thus, appropriate measures could be taken to impede respiratory morbidities. Settings and Design: Cross-sectional study in a semi-urban area. Methods: done among 260 subjects working for more than a year, while ones already on medication for respiratory illnesses were excluded. Statistical Analysis Used: Excel was used for data tabulation and Chi-square tests for significance, with the level of significance at α = 0.05. Results: A high prevalence of respiratory morbidities, with 64.62% of the study population showing one or more respiratory morbidities, was noted. Cough (23.85%), followed by breathlessness (22.31%), and were highly prevalent. The study revealed significant relationships between Peak Expiratory Flow Rate (PEFR) and age, BMI, Total Exposure Period (TEP), respiratory morbidities, and addictions. However, no significant relation was found between PEFR and the type of shop, whereas prevalence was high on the roadside as compared to closed shops. Conclusions: The prevalence was high in subjects with shops situated on the roadside as compared to the closed ones. This was due to the high TEP, as the shopkeepers worked for longer durations owing to their socioeconomic demands. Therefore, the Total Exposure Period (TEP) plays a greater role than the type of shop.
Knowledge and Preventive Measures of Occupational Hazards among the Workers Working in Different, Factories, Industries and Health Care Settings: A Review
Authors: Hazarika Darshana , Praveen Uppu
Published: December 2023

An occupational health hazard is described as a possible harm to a person’s health after leaving a toxic workplace, which is a serious public health concern. The most frequent risks in their workplace include eye fatigue, eye pain, neck injuries, musculoskeletal issues, stress, professional burnout, anxiety, depression, and some common psychological hazards that might arise during dental treatment. A total eight numbers of relevant original descriptive (cross-sectional) studies of the recent five years restated to knowledge and preventive measures of occupational hazards among the workers working in different, factories, industries, and healthcare settings were selected for this present review. The knowledge of the employees regarding occupational hazards is very important for the provision and establishment of occupational health and safety measures.
Genetyczne i molekularne podłoża rozwoju glejaka
Authors: Panek Przemysław , Jezela-Stanek Aleksandra
Published: December 2023

Stage IV glioblastoma is the most frequently diagnosed and the worst prognosis tumor of the central nervous system (CNS). Patients suffering from this type of cancer usually survive several months with the use of surgical treatment, radiotherapy and chemotherapy. The development of glioblastoma is determined by a number of mutations, the most common of which are the p16, p19, p53, pRB, PTEN, PDGFR, CDK4 and EGFR protein genes as well as the loss of heterozygosity on chromosomes 10, 17 and 19. The occurrence of mutations within the IDH1 and IDH2 genes and increased methylation of MGMT promoter improves patient survival, but few patients live more than 3 years after diagnosis. The most important cell signaling pathways in glioblastoma are PI3K/Akt/mTOR and Wnt/β-catenin, which play a key role in tumor cell function. However, these cells are highly resistant to anticancer drugs, including inhibitors of cell signaling pathways. Currently, the potential methods of effectively combating malignant gliomas are alternating electric field therapy and the implementation of new immunotherapeutic strategies.
Struktura molekularna i funkcje wakuolarnych enzymów procesujących w ontogenezie roślin
Authors: Przybylak Marta , Wleklik Karolina , Stafiej Alan , Borek Sławomir
Published: December 2023

Vacuolar processing enzymes (VPEs) are plant proteases belonging to the C13 protease family. The specific activity of VPEs was characterized by comparing them to animal caspases. VPEs perform many important functions at various stages of plant ontogenesis, playing a role not only in the proper development of the plant organism but also in plant reactions to biotic and abiotic stress factors. A particularly important role of VPEs is noted in the processing of vacuolar proteins, enabling the production of their mature and active forms. VPEs are involved in programmed cell death, but despite residual evidence, we also suggest that VPEs are involved in autophagy. Based on literature data on autophagy in yeast, we formulate a hypothesis that VPEs during autophagy in plant cells are involved in the degradation of autophagic bodies - one of the final stages of autophagy.
Sirtuina 1 jako potencjalny cel molekularny resweratrolu w wybranych chorobach
Authors: Frankenstein Hanna , Robak Jakub , Lewandowska Urszula , Owczarek Katarzyna
Published: December 2023

Cancer, type 2 diabetes, cardiovascular and neurological diseases are disorders commonly classified as diseases that have a significant impact on the length and quality of human life. Sirtuins play an important role in their pathogenesis and complications. Numerous studies indicate that modulation of the expression of these proteins can slow down the processes of aging and cell death, prevent inflammation, and regulate metabolic processes, and consequently modify the progression of the disease. One of the best-known sirtuins is sirtuin 1, whose strongest natural activator is resveratrol. The development of alternative therapies involving natural compounds such as resveratrol is highly desirable due to the significantly lower number of side effects compared to conventional therapies. Therefore, this review summarizes the possible benefits of resveratrol as a sirtuin 1 activator in the prevention and treatment of human diseases based on the results of the studies conducted so far.
Antimicrobial Silver Zeolite and Urinary Incontinence in Patients with Alzheimer’s Disease
Authors: Bidaki Reza , Mojarrab Behnaz , Sadeh Maryam
Published: December 2023

The Article Abstract is not available.
Associations between Sensory Loss and Depressive Symptoms in a Longitudinal National Study of Ageing Adults in Thailand
Authors: Pengpid Supa , Peltzer Karl
Published: December 2023

Introduction: Sensory loss and depressive symptoms (DS) may be an increasing concern in ageing adults. Some previous studies in China found bidirectional associations between sensory loss and DS, but we lack information on this relationship in Southeast Asia. The purpose of this study was to assess the bidirectional association between sensory loss and DS in a longitudinal study in Thailand.
 
Methods: The responses of participants (≥ 45 years) of two consecutive waves (2015 and 2017) of the Health, Aging and Retirement in Thailand (HART) study were analysed. Sensory loss was assessed with self-reported questions and DS with the Center for Epidemiological Studies Depression scale.
 
Results: The analytic baseline sample included 3708 participants (median = 66 years) who responded to the 2015 and 2017 survey. The prevalence of vision, hearing and dual sensory loss were 25.4%, 13.3% and 7.9%, respectively, and the prevalence of DS was 12.3%. In the final model, adjusted for relevant confounders, vision, hearing, and sensory loss at baseline were positively associated with incident DS (AOR: 1.34, 95% CI: 1.01 to 1.74; AOR: 1.71, 95% CI: 1.23 to 2.38; and AOR: 1.80, 95% CI: 1.20 to 2.69, respectively). DS at baseline was not significantly associated with incident vision, hearing or dual sensory loss.
 
Conclusion: Baseline vision, hearing, and dual sensory loss increase the odds of incident DS, but baseline DS did not significantly increase the odds of incident vision, hearing, or dual sensory loss among ageing adults in Thailand.
Does COVID-19 Change the Food Habits of the Rural Elderly? A Cross-Sectional Study in Khulna District of Bangladesh
Authors: Jabbar Abdul , Kabir Ripul
Published: December 2023

Introduction: COVID-19 has changed all the routine works of human beings around the globe. The food habits of the elderly are changing due to various reasons. The purpose of this study was to find out the factors influencing food habit changes due to the pandemic.
 
Methods: A non-experimental research design, a survey, was executed at Sachibunia, Nijkhamr, Krishnonagar, and Raingamari villages under Batiaghata Upazila in the Khulna District of Bangladesh. Following a simple random sampling technique, data were collected through a field survey using an interview schedule. To show the relations between/among the variables, the chi-square/Fisher exact test was performed.  For measuring the degree of relations of those variables, Binary Logistic Regression  was used to find out the factors of food habit changes with a 95% confidence interval. For the model, p < 0.05 was considered statistically significant.
 
Results: The study reveals that 39% of the elderly changed their food habits during COVID-19. Except for the sex and employment status of the elderly, all the sociodemographic factors of this study were associated with food habit changes. Among these sociodemographic factors, age (OR = 2.51, 95% CI, 1.22-5.18), religion (OR = 2.07, 95% CI, 1.13-3.78), spouses' occupation (OR = 3.73, 95% CI, 1.90-7.32), and family head (OR = 3.74, 95% CI, 1.43-9.75) of the elderly influenced their food habits changes.
 
Conclusion: The socio-demographic and economic situations were responsible for the elderly’s food habits changes.
Integrated Bioelectrodialysis for Hydrogen Production from Biological Waste
Authors: Gholizadeh Abdolmajid , Foroughi Maryam , Ghorbanian Mahdi , Poureshgh Yousef , Yektay Sama
Published: December 2023

The Article Abstract is not available.
Characteristics of Airborne Particles and Bacteria in Hospital Indoor and Outdoor Air
Authors: Atoof Fatemeh , Gholipour Sahar , Shamsizadeh Zahra , Amirimoghaddam Mohsen , Mirzaei Nezam , Nazari-Alam Ali , Rabbani Davarkhah , Baziar Mansour , Hoseindoost Gholamreza , Mostafaii Gholamreza , Bahrami Abbas
Published: December 2023

Introduction: Given that hospital air is one of the important environmental sources for transmission of microorganisms, the importance of airborne transmission in the epidemiology of hospital-acquired infections (HAIs) has gained attention in the past two decades. Therefore, the present study aims to determine the concentration of bacteria in association with airborne particulate matter (PM) in the outdoor and indoor air of two hospital wards.
Materials and methods: The GRIMM 1.109 dust monitor and the Andersen one-stage viable impactor were used for particle counting and bioaerosol sampling, respectively.
Results: The average levels of airborne bacteria sampled from outdoor air were 33 colony-forming units (CFU/m3), and in the air samples of medical and infectious disease wards, they were 76 and 85 CFU/m3, respectively. Staphylococcus spp. and Acinetobacter spp. were the most prevalent bacteria in the samples. Statistical analysis showed a significant association between PM2.5, and PM10 particle mass concentrations and airborne bacteria concentrations in indoor air samples (P-value < 0.05).
Conclusion: Some bacterial agents of HAIs existed in hospital air and may be problematic for immunocompromised patients. Higher levels of bacteria in indoor air compared to outdoor air may indicate that the bacteria were of indoor origin, such as the presence and activities of people. Moreover, the results showed that particle counting may be a useful tool for airborne bacteria monitoring.
Studies of the Properties of New Electrospun Based on PVA-PEG Polymer Systems Electrolytes for Energy Storage Devices
Authors: GUL Ramat , MAHMOOD Wan Ahmad Kamil
Published: December 2023

Solid polymer electrolytes (SPEs) have been considerably investigated due to various electrochemical device applications. Most of the SPEs comprise polymer as a host material to provide strength and good mechanical stability and salt that transfers charge carriers to cause conductivity. Nanocomposite solid polymer electrolyte membranes based on poly(vinyl alcohol) (PVA)-poly(ethylene glycol) (PEG) blend complexed with LiClO4 and nanofillers Al2O3 at different weight percent ratios have been obtained by using electrospinning method. The conductivity and structural properties of the different systems have been characterized by using various experimental approaches such as X-ray diffraction (XRD) and Fourier transform infrared FTIR spectroscopy. The ionic conductivity of the systems has been measured by using an LCR meter in a temperature ranging from 298 to 353 K. Maximum ionic conductivity of 1.58 × 10-4 S cm-1 at room temperature has been observed for the system of PVA-PEG-LiClO4-Al2O3 (50-25-15-10) with 15 wt% weight percent of LiClO4 salt in PVA-PEG blend matrix. The ac conductivity report indicates that the ionic conductivity of the PVA-PEG-LiClO4-Al2O3 complex is influenced by the concentration of LiClO4. The effect of temperature on the ionic conductivity of polymer electrolyte complexes has been estimated by changing the temperature ranging from 298 to 353 K. However, the conductivity of the nanofiber polymer electrolyte systems increases with the rise of temperature, and the maximum conductivity of 1.58 × 10-2 S cm-1 has been recorded at 353 K. The temperature-dependent conductivity follows the Arrhenius behavior.
Prognostic value of non-alcoholic fatty liver disease in patients with pulmonary embolism
Authors: KAÇMAZ KAT Nurcan , SENSOY Nur Ozer , KUZEYTEMİZ Mustafa , DEMİR Ömer Furkan
Published: December 2023

Objectives: Pulmonary embolism (PE) is an important disease due to its mortality and morbidity-related clinical conditions. Patients with a high risk of death within 30 days are discriminated against with the help of various clinical scores. Non-alcoholic fatty liver disease (NAFLD) has been found to be associated with atherosclerosis. We aimed to investigate the effect of NAFLD on disease severity and early death rate in patients with pulmonary embolism.
Methods: This retrospective study includes patients who applied to the emergency department with suspected pulmonary embolism and whose diagnosis was confirmed according to the results of the examination. In addition to confirming the diagnosis of PE, hepatic steatosis was detected and graded by tomographic examination of the liver and spleen. Disease severity was stratified by Simplified Pulmonary Embolism Severity Index (sPESI).
Results: A total of 165 patients (105 with sPESI≥1 and 60 with sPESI<1 controls) were included. The rate of mortality was 12% (n=13) in the sPESI≥1 group. The prevalence of NAFLD was 64% and the prevalence of hepatosteatosis was similar according to disease severity and prognosis (67% vs. 58%; P=0.28 and 69% vs. 63%; P=0.77). Besides the effect of disease severity; chronic lung disease (CLD) and chronic kidney disease (CKD) were independently associated with poor prognosis by multivariate analysis [3.71 (1.02-13.46); P=0.04 and 15.89 (2.57-98.35); P=0.003].
Conclusion: No association between disease severity and prognosis was observed with NAFLD in acute PE disease.
O tożsamości sztuki sportu
Authors: Lipiec Józef
Published: December 2023

Z tradycji Igrzysk w Olimpii, jak również nowożytnego ruchu olimpijskiego, nie sposób odnieść się do walorów i dziedzictwa Grecji jako katalogu wartości formujących współcześnie sport. Biorąc to pod uwagę celem podjętych rozważań jest próba odpowiedzi na pytania: Kiedy i dlaczego nastąpił proces zbliżenia sportu do sztuki? Co decyduje o tożsamości poszczególnej dziedziny sportu jako fenomenu przynależności do tej samej sfery bytu i tego samego pola doświadczeń ludzkich? Kto jest artystą wpisanym w krąg światła sztuki? Odpowiedzi na te pytania podejmowane będą przez pryzmat koncepcji jedności cnót ludzkich, a także poprzez odwoływanie się do tradycji Olimpii z perspektywy historycznej, aksjologicznej oraz esencjalnej. Oryginalnie ujęta cielesność jest tworzywem sztuki sportu jako materialnego fundamentu całości swoistej i samodzielnej.
Incidence and Population Dynamics of Various Associated Insect-pests of Late Direct Sown Paddy, Oryza sativa L. at Gajapati, Odisha
Authors: Yadav Manish K. , Satapathy Satya Narayan , Priyadarshini Priyanka , Tripathy Barsha , Lenka Biswajit , Behera Kiran Kumar , Paikaray Subhashree Subhasmita
Published: December 2023

Background: Rice is the most important staple food of the world. Rice production is now-a-days reduced due to insect pest attacking to the crop in various growing stages. There are more than 1400 pest species, which are cause great menace to the rice cultivation. Incidences and abundance of pests in rice is growing day by day due to climatic change and excess use of chemical pesticides. In late direct sown paddy is also facing the insect pest problems in different growing stages. The study aimed to layout the different pest’s incidence and population dynamics as well, on various stages of direct sown paddy. The knowledge of incidence timing for various pests can be further utilized for the suitable management. Methods: The present study has been conducted during the late Kharif seasons of 2021-22 for 11 most widely grown paddy cultivars of farmers field around the locality of MS Swaminathan School of Agriculture, Centurion University of Technology and Management, Paralakhemundi, Odisha. The surveyed cultivars were Anjali, Arize 8433, BAM-6, Bhuban, Chandra, CR Dhan 100, Varsha Dhan, CR Dhan 306, Sumit, Luna Sankhi and Vandana, respectively. These cultivars were surveyed for the abundance of various associated insect-pests at two different crop growth stages. Result: The results revealed that the incidence of various pests namely Scirpophaga incertulus, Orseolia oryzae, Cnaphalocrocis medinalis, Parapoynx stagnalis, Dicladispa armigera, Leptocorisa acuta, Grasshoppers, Nezara virdula, Nephotettix virescens, Melantis leda and Mythimna separate was found to be significant for both the growth stages. The maximum population on late direct sown rice was found to be of Scirpophaga incertulus (3.67) and Orseolia oryzae (2.67) at the vegetative stage of rice while pests such as Cnaphalocrocis medinalis (6.34), Leptocorisa acuta (7.34) and Mythimna separate (5.67) were recorded maximum during the milking stage of rice.
Role of Organic Fertilizer Types on Nutrient Absorption and Soybean Yield in Teak-based Agroforestry Systems
Authors: Setyaningrum D. , Budiastuti M.T.S. , Purnomo D. , . Sudadi
Published: December 2023

Background: Indonesia’s soybean production is insufficient to meet the demand for domestic soybean consumption as 86.4% demand is met from imports. Climatic conditions strongly influence soybean production and its quality in Indonesia, so the agroforestry system are used to to boost soybean production. However, the weakness of the agroforestry system is the low light intensity resulting in lower production. This study examines the effect of various organic fertilizers on nutrient uptake and soybean yields in teak-based agroforestry systems. Methods: The study used a complete randomized block design with one factor, namely the type of fertilizer with seven levels, namely inorganic fertilizer (Urea 50 kg/ha, SP36 100 kg/ha and KCl 100 kg/ha), Indigofera tinctoria compost, corncob compost, peanut green manure, chicken manure, goat manure and cow manure (dose of 5 tons/ha) and repeated three times. Result: The type of fertilizer affects nitrogen and potassium uptake, root length and biomass, number of leaves, plant biomass and 1 ha soybean yield in a teak-based agroforestry system. Indigofera tinctoria compost produced the highest nitrogen and potassium uptake, 13.83 g and 2.77g. Nitrogen uptake is positively correlated with root length and plant biomass. The highest soybean yield in the peanut green manure treatment was 1.6 tons. Organic fertilizers increased nutrient uptake and soybean yields under teak stands compared to inorganic fertilizers.
Nutritional Evaluation of Legume Based Traditional foods of Palampur region of Himachal Pradesh
Authors: sharma Rekha , Dhaliwal Y.S.
Published: December 2023

Background: The present investigation was undertaken with the objectives to document the traditional food recipes, process/preparation, nutritional evaluation and development of protocols for the standardization of the recipes to minimize the nutrient losses. Methods: Three blocks viz. Baijnath, Panchrukhi, Bhawarna and Palampur itself were selected. A questionnaire was used to collect the relevant information on traditional foods from 120 respondents. Legume based traditional foods were also analyzed for their nutritional component with standard methods. Result: In legumes black gram contained highest crude protein content (26.26%). Moisture content was highest in kidney beans (12.65%), whereas in bengal gram dal it was lowest (9.69%). Fat content was highest in Bengal gram whole (6.07%) whereas it was lowest in Black gram (2.20%). Protein content highest in black gram (26.26%), whereas it was lowest in Bengal gram dal (22.35%). Crude fiber was highest in kidney beans (5.37%) and lowest in black gram (0.99%). chickpea had highest total ash content (5.19%) whereas it was lowest in Bengal gram whole (2.73%Recipes analysis result showed that pakodu contained high crude protein content i.e. 27.44 per cent, whereas Crude fat content was highest in mukund badi madra (22.17%). Kidney beans had highest phytic acid content (96.74 mg/100 g), whereas it was lowest in Bengal gram dhal (37.99 mg/100 g). Total phenols were highest in chick peas (117.16 mg TAE/100 g), where as lowest was in kidney beans (92.95 mg TAE/100 g). Oxalates were highest in kidney beans (0.91 mg/100g) whereas, lowest was chick peas (0.24 mg/100 g).
Human Factors Engineering and Usability as Key Drivers for Design of Device Suited for Urine Filtration and Enrichment
Authors: Jordaens Stephanie
Published: December 2023

Evidence-based practices (EBPs) are not always straightforward to implement in a design process, as impacts can be difficult to assess in practice and appropriate methods are not yet established. User-centered design (UCD) offers opportunities to improve implementation of EBPs. UCD refers to the use of rigorous and validated engineering tools to design technology interfaces focused on user goals, such as device safety, effectiveness, efficiency, and user satisfaction. UCD has the potential to improve six core elements of patient-centered care: (i) education and shared knowledge, (ii) free flow of information, (iii) patient engagement, (iv) teamwork, (v) attention to non-medical aspects of care, and (vi) respect for patient preferences. Technological advances in medicine over the past few decades have provided patients with a variety of inventions, such as electronic health record patient portals, home-based medical devices, and smartphone apps. Effective application of UCD principles results in patient-centered inventions that are more likely to ease patients’ treatment burden, improve their care experience, increase patient engagement, and enable patients to become more self-sufficient. Here, the URICH device design process is used as case-example to demonstrate the inclusion of usability testing and all users as early as possible in the product design and development process.
Laporan Kasus: Infeksi Cacing Strongyloides pada Kucing Peliharaan
Authors: Wisana Kadek Adya Arsa , Widyastuti Sri Kayati , Erawan I Gusti Made Krisna
Published: December 2023

Strongyloidiasis adalah penyakit yang disebabkan oleh cacing nematoda Strongyloides sp. Hewan kasus adalah kucing peliharaanberjenis kelamin betina, berumur tujuh bulan,dengan bobot badan 2,24 kg. Kucing kasus mengalami diare selama satu minggu setelah dua minggu dipelihara yang disertai dengan penurunan nafsu makan. Hasil pemeriksaan fisik menunjukkan gejala dehidrasi, lemas, mukosa mulut dan mata pucat, serta pembesaran pada abdomen.Pada pemeriksaan feses dengan metode natif ditemukan telur cacing Strongyloides sp..Pemeriksaan darah lengkap menunjukkan kucing kasus mengalami leukositosis. Kucing kasus didiagnosis menderita Strongyloidiasis. Penanganan kucing kasus dilakukan dengan diberikanantiparasit ivermectin0,2mg/kg BB, terapi suportif dengancyanocobalamin250 mcg/ kg BBsecara intramuskuler dan diulang duahari sekali.Hasil pengobatan selama satu minggu menunjukkan perkembangan yangbaikditandai dengan kucing kasus sudah tidak mengalami diare, capillary refill time(CRT) kurang dari 2 detik, turgor kulit normal, mukosa mulut dan mata berwarna merah muda, serta abdomen kembali normal.Pemeriksaan feses kembali dilakukansetelah satu minggu pengobatan sebagai evaluasi. Pemeriksaan feses dilakukandengan metode natif dan tidak ditemukan telur cacing Strongyloides sp.Untuk mencegah terjadinya infeksi kembali disarankan untuk memberikan obat cacing secara berkala setiap tigabulan sekali.Perbaikan nutrisi perlu dilakukan dengan memberikan pakan yang baik serta lingkungan yang lebih nyaman.
Chromosome 9 aberrations diagnosed at a pediatric hospital in Tabasco, Mexico
Authors: Rodríguez García Diana Saraí , Gómez Sandoval Norma , Diaz Martínez Rubicel , Rivera Angles Miriam Margot , Huerta García Elizabeth , Gómez Valencia Luis
Published: December 2023

Objective. To determine the frequency of patients diagnosed with chromosome 9 disorders in a pediatric hospital between the years 2012 and 2022.
Materials and methods. A cross-sectional and descriptive study was performed in 2932 patients who attended the genetics consultation of a pediatric hospital in Tabasco, Mexico, from January 2012 to December 2022, based on the results of chromosomal diagnosis in peripheral blood.
Results. Chromosomal alterations were present in 14.76% (433/2932). The most frequently involved chromosome was number 21 in 83.37% (361/433), followed by sex chromosome X with 5.31% (23/433) and chromosome 9 with 3.69% (16/433).  Regarding chromosome 9, 50% (8/16) corresponded to morphological variants (9qh+), followed by pericentric inversion in 3 of the cases (18.75%), deletion in 2 (12.5%), insertion in 1 (6.6%), ring in 1 (6.6%), and a shunt (6.6%). 
Conclusion. The cytogenetic results found, according to the patients' reasons for referral, suggest the performance of peripheral blood karyotyping as a useful tool in the diagnosis of diseases with genetic suspicion.
 
Key words: Chromosomal inversion; Karyotype; Infertility.
A construção histórica e social da infância: um diálogo entre alguns dos principais pesquisadores contemporâneos que estudam temas relacionados à cultura das crianças e à/s infância/s
Authors: Silva Camila Ferreira da , Maia Janaina Nogueira
Published: December 2023

Esta pesquisa teórico-bibliográfica busca identificar os recentes estudos sobre o universo infantil e ilustra como compreendê-lo a partir da construção histórica e social. Permeia uma pesquisa a partir do Grupo de Estudo e Pesquisa Crianças e Infâncias (GEPCI), da Universidade Federal de Mato Grosso do Sul – Campus Aquidauana (UFMS/CPAQ). Orienta-se na perspectiva da história social da infância e da criança, em que o foco se entrelaça na preocupação e necessidade de investigar a origem dos conceitos, levando-se em conta o contexto, a produção e suas relações sociais, bem como um panorama das concepções dos principais pesquisadores que estudam temas relacionados à cultura das crianças e à/s infância/s, como: Manuel Sarmento (2004), Alan Prout (2010), Willian Corsaro (2011), Régine Sirota (2006) e Jens Qvortup (2011). Dessa forma, o registro em questão sublinha o que pensam tais pesquisadores e como estão, para a sociedade, os estudos da criança, sobretudo a sociologia da infância. Para efeito de investigação, o conjunto de contribuições dos pensadores aqui reunidos expressa o vigor e o desafio de um grupo disposto a estudar a infância sob uma nova ótica: dando à criança um protagonismo inédito. Assim, este estudo é uma oportunidade para o conhecimento das perspectivas adotadas por um grupo de investigadores que têm ajudado a renovar o debate nas ciências sociais e humanas de nosso tempo e que, de alguma forma, sejam capazes de sublinhar novas investigações e instigar práticas pedagógicas mais sensíveis e respeitosas às possibilidades e aos direitos das crianças.
STRICT LIABILITY FOR BREACH OF THE LAWS OF THE WAR BETWEEN ISRAEL AND PALESTINS IN GAZA
Authors: Budi Dio Prasetyo , Kaloko Ilhamda Fattah
Published: December 2023

Feuds and conflicts that occur in the world are dynamics that occur and things that cannot be avoided by the state. Conflicts between Israel and Palestine occur repeatedly, but the realization of international accountability has not been in accordance with existing rules. The existence of events that resulted in casualties in the war must be accounted for by Israel as a State, as well as the individuals involved. As a result of this action, the perpetrators of war crimes must be held accountable under international law. The problem with this article is what is the responsibility of the State of Israel for violating the laws of war? The conclusion of this article is: There is no responsibility of the State of Israel for violations of the laws of war, from every violation of international law Israel remains free from punishment, of course this is related to international politics which is considered very inhumane. Israel has not ratified the Rome Statute, so the ICC certainly will not be able to process cases of war crimes committed by Israel, making it difficult to hold Israel accountable for violations of the laws of war. In order for the implementation of international humanitarian law enforcement for perpetrators of war crimes, it can be carried out through Internationally Wrongful Acts, it can be realized by carrying out full reparations for losses in the form of restitution, compensation and satisfaction, either separately or in combination.
OPTIMIZATION OF NATURAL CATALYSTS IN OIL PRODUCTION FROM PLASTIC WASTE PYROLYSIS
Authors: Afriadi Denni , Muhammad Yasin Fazrul
Published: December 2023

This study was conducted to determine the effect of the amount of catalyst on yield from the pyrolysis of Polypropylene (PP) type plastic waste and to determine the characteristics of plastic waste pyrolysis oil which includes the physical and chemical properties of pyrolysis oil. The physical properties tested include viscosity, fire point, flash point, pour point, density, and water content while the chemical properties are compounds contained in pyrolysis oil using Gas ChromatoChromatography -Massmetry (GCMS) and knowing its calorific value. The research was conducted on the type of High-Density Polyethylene (HDPE), namely Polypropylene (PP) which was hydrolyzed in a batch reactor using an incinerator where heating originated from outside using wood powder and LPG. The ratio of raw materials used is as much as 1 kg of plastic with a variation of zeolite catalyst 0.25; 0.5; 0.75; 1 in kg. The results showed that the more catalysts added, the more pyrolysis oil was produced. The results of measuring oil at LEMIGAS kinematic viscosity at 40oC are 1.556 cST, 42 oC fire point, PMCC 26 o C flash point, pour point -42 o C, density at 15 o C 0.7857 g / cm3, and water content is 507.54 ppm . While the hydrocarbon compounds produced are pentene, heptane, and cyclohexane which have flammable properties. The calorific value produced from this pyrolysis oil is 40.947 Mj / Kg. The maximum amount of plastic oil volume is obtained by using 1 kg of raw material with 1 kg of 955 ml zeolite catalyst.
FORMULATION OF SUNSCREEN BODY LOTION FROM MORINGA ( Moringa oleifera L.) LEAF EXTRACT
Authors: Taebenu Desi Adriyanti Nina Taebenu , Arpiwi Ni Luh , Sudatri Ni Wayan
Published: December 2023

The way to avoid UV radiation is to use sunscreen lotion. Moringa plant (Moringa oleifera L.) contains 46 types of antioxidants and 36 anti-inflammatory compounds that have the potential as sunscreens. The purpose of this study was to determine the effect of the type of concentration of Moringa leaf extract on the SPF value, to analyze the quality of the lotion produced and the level of probandus preference for sunscreen lotions. The research was conducted at the Laboratory of Plant Physiology, FMIPA Unud, Laboratory of Chemical Analysis and Pharmaceutical Analysis, FMIPA Unud, and the Integrated Research Laboratory of Unud. The design used in this study was a completely randomized design (CRD) using 0% concentration of Moringa leaf extract; 0.5%; 1%; 1.5% and 2%. Parameters tested include; organoleptic test, homogeneity, pH, viscosity, hedonic and the determination of SPF number with in vitro technique. The results of the study show that the pH, homogeneity and viscosity tests of F0, F1, F2, F3 and F4 have met the requirements of SNI. The SPF value of each formula is 5.6780; 9.7605; 19.0299; 38.0369; 68.8832. Statistical analysis of pH and viscosity showed that there were different variations in each formulation. Statistical analysis of the hedonic test showed that there was no difference in variation in each formulation. As the addition of moringa leaf extract to sunscreen lotion, the higher the SPF number.
A REVIEW: A ROLE OF CAPSAICIN TO REGULATING T2R AND TRPV1 AND ITS ASSOCIATION IN CANCER DEVELOPMENT
Authors: Rokhman Ardi Putra Faruk , Anis Irmawati
Published: December 2023

Cancer is one of the leading causes of death in the world. It is estimated that this disease has caused 10 million deaths. The cause of the development of cells into cancer is still a mystery until we know that cancer is a disease that occurs due to an imbalance of molecular genes and cell receptors. Bitter taste receptors (T2R) are known to be expressed outside the taste buds and detect the perception of a bitter taste. These receptors are known to be involved in the mechanism of cancer cell development. Capsaicin is involved in a wide variety of genes that regulate the life cycle and growth of cancer cells. The activity of Capsaicin in inhibiting cell growth can be observed through various target genes, such as oncogene signaling pathways and tumor-suppressor genes. The systematics in this article is carried out using four electronic databases, namely Google Scholar, PubMed, ResearchGate, and NCBI. The keywords used are "capsaicin" combined with "T2R", "T2R8", "TAS2R", "TRPV1", "GPCRs" and also "Cancer", "Cancer cell line", "Mice", "Rat", "Man". Capsaicin affects the activity of normal cells and cancer cells through the TRPV 1 and T2r pathways. Through the TRPV1 pathway, Capsaicin increases intracellular calcium and disrupts the mitochondrial matrix. Via the T2r pathway, Capsaicin causes IP3, which increases intracellular calcium through endoplasmic reticulum stress.
COMBINATION OF ELECTROACUPUNCTURE THERAPY WITH HERBAL ROSEMARY (ROSEMARINUS OFFICINALIS L.) IN CASE OF OBESITY
Authors: Puspita Widya Retnaning , Rahman Abdul , Suhariningsih  , Astuti Suryani Dyah , Fitriyah Nurul , Winarno  , Katherine  , Alma Ahmad Faizin , Zulkarnaen Mohammad
Published: December 2023

Obesity or overweight is a condition that occurs when the quantity of body fat tissue compared to total body weight is greater than the normal state. Diet, exercise, psychological factors, heredity, hormones, and drug side effects are a few of the factors that might cause obesity. Gastric heat syndrome was present in the patient in this case study. The patients received electrostimulator-assisted acupuncture treatment 12 times for a total of 15 minutes at the following points: Fenglong (ST40), Neiting (ST44), Sanyinjiao (SP6), and Quchi (LI11), and was also given the herbal remedy rosemary (Rosmarinus officinalis L.) for 28 days, taken twice daily. Through the activation of PPAR- g, inhibition of prankeas lipase, and inhibition of pre-adipocyte development into adipocytes, carnosic acid, a component of rosemary, helps people lose weight. Additionally, carnosic acid stimulates the excretion of fat in feces. According to the case study results, the patient's body weight dropped from 77.6 kg to 73.9 kg. This indicates that acupuncture treatments at the points Fenglong (ST40), Neiting (ST44), Sanyinjiao (SP6), and Quchi (LI11) together with the administration of rosemary herbs can result in weight loss of up to 3.7 kg over the course of 28 days.
The culture of reading for acquisition and learning of content knowledge for English language and literature in English in higher education
Authors: Ramolula Kabelo , Nkoane Milton
Published: December 2023

This study aims to explore the culture of reading literary texts in higher education and the strategies that can enhance the acquisition and learning of the content knowledge for both English Language and Literature in English. The study adopted an interpretivist paradigm and qualitative research design. The study is qualitative in nature. Language in/for/with content and schema theories form the basis for the study. The former holds that language cannot be acquired outside content whilst schemata are stored mental structures that determine the acquisition of new knowledge; thus, literary content knowledge may not be acquired/learned outside linguistic and communicative competencies and vice versa. Data were collected from the relevant literature from the past six years. It was interpreted and analysed thematically. The results showed that students' habit of reading is poor which affects their academic performance. In addition, new technological devices make learning easier and more accessible, but it negatively affects students' ability to read authentic texts for information and entertainment. The study therefore concludes that university students do not read literary texts because of the bad use of information and communication technology. However, the use of digital libraries could improve the situation. The findings suggest that institutions of higher learning should have strategies to engage linguists and literary scholars in the habit of reading literary texts. University libraries should be equipped with relevant and updated digital reading materials.
Competency in information and communication technology and use of e-recruitment portal in Dodoma city, Tanzania
Authors: Msacky Richard , Mwangata Isa
Published: December 2023

The recruitment functions of human resources have transitioned from a conventional paper-based system to utilizing the internet through electronic recruitment portals. Electronic recruitment is widely recognized as a strategy that organizations utilize to attract people who possess the necessary education, experience, and abilities. The objective of this study was to evaluate the factors that influence job-seekers' utilization of e-recruitment platforms for job applications in the public sector of Tanzania. The study employed a cross-sectional survey approach to gather both quantitative and qualitative data from Dodoma City. A standardized questionnaire was used to collect quantitative data from 384 job applicants. The interview method was used to acquire qualitative data from ICT officials of PSRS. Job-seekers were chosen through the utilization of a random sample technique, whereas PSRS ICT officials were deliberately recruited. The study's findings indicate that there is a positive and significant correlation between job seekers' use of e-recruitment and their ICT competencies. Thus, the study determined that ICT competencies play a vital role in determining the utilization of the e-recruitment portal of PSRS for job applications. Therefore, the study suggests that PSRS should revamp its portal to enhance its user-friendliness.
Assessing the imperative for school social workers: insights from principals and circuit managers in Mankweng circuit, South Africa
Authors: Sibise Katekani , Mathebula Wiseman Ntlhari
Published: December 2023

This research study investigated the critical role of school social workers within the educational landscape of Mankweng Circuit, South Africa. School social workers play a pivotal role in addressing the multifaceted challenges faced by students, their families, and school communities. Through a qualitative research approach, we conducted in-depth interviews with principals and circuit managers to explore their perspectives on the role of school social workers in promoting holistic student development, improving school climate, and addressing socio-emotional barriers to learning. The findings uncover the multifaceted challenges faced by school social workers, including limited resources, high caseloads, and the need for ongoing professional development. The implications of this research are significant, shedding light on the critical need for recognising and investing in the roles of school social workers in South African education. The insights gained from this study can inform policymakers, educators, and stakeholders in the field of education on the imperative of integrating school social workers into the educational system as vital contributors to the overall success and well-being of students. Ultimately, this research contributes to the ongoing discourse on strengthening the educational support system in South Africa and beyond.
Corporate ESG issues and retail investors’ investment decision: a moral awareness perspective
Authors: Nafisa Rounok , Mohammad Ashraful Alam , Qian Aimin
Published: December 2023

The specific goal of this study is to find out how retail investors consider company ESG issues while making investment decisions, with their moral awareness (MA) serving as a moderator. The framework's foundations are the norm activation model (NAM) and the theory of planned behavior (TPB). The report is based on a questionnaire survey that was completed by 599 retail investors in Dhaka and Chattagram, Bangladesh. To examine the data and verify the theories, the PLS path modeling approach is employed. Six hypotheses are investigated using structural equation modeling; five are found to be significant and one to be non-significant. All of the hypotheses are positive. The findings of the research demonstrate that when making investment decisions, investors take a company's social, environmental, and governance issues into account. The moral awareness of investors seems to influence their investment decisions as well. By presenting empirical data on the relationship between business ESG issues and investment decisions with moderating impacts on investors' moral awareness, the paper advances the field of behavioral finance research. It implies that corporate advertising tactics may support global reporting requirements, draw impact investors, and promote moral and environmental education. To safeguard ESG concerns and promote sustainable growth of the capital market and economy, governments should enact laws, rules, and directives.