bluuebunny/crossref_metadata_2025 huggingface dataset:
Sürdürülebilir Kalkınma: Nitelikli Eğitim Hedefinde Kamu Eğitim Harcamalarının Rolü
Authors: Taşdoğan Bilgen
Published: September 2024

Maliye politikasının temel amaçlarından birisi olan ekonomik kalkınmanın gerçekleşebilmesi için fiziki sermayeye ek olarak beşeri sermayenin de katkısına ihtiyaç bulunmaktadır. Beşeri sermayenin katkısını artırmanın yegâne yolu da nitelikli eğitim imkânlarının gelir ve fırsat eşitliği temelinde tüm bireylere sunulması ile mümkündür. Ayrıca bir kamusal mal olan eğitim hem özel hem de kamusal mal özelliğine sahip olduğu için yarı kamusal mal ve hizmet olarak tanımlanmaktadır. Dolayısıyla özel kesime ek olarak eğitim harcamalarında kamunun da sorumluluk üstlenmesi bir zorunluluk olarak görülmektedir. Bu çalışmada kamu eğitim harcamalarının GSYH içindeki payının Sürdürülebilir Kalkınma Hedeflerinden biri olan nitelikli eğitim hedefi için belirlenen mesleki eğitime ve yükseköğretime kayıt oranı göstergelerine etkisi incelenmiştir. Elde edilen bulgulara göre kamunun eğitim harcamalarının GSYH içindeki payı arttıkça; mesleki eğitime katılım özellikle mesleki eğitime katılımın düşük olduğu ülkelerde daha çok artmasına katkı yaparken üniversiteye katılımın düşük olduğu ülkelerde de pozitif bir etki yaratmaktadır. Bunların aksine üniversiteye katılım oranının en yüksek olduğu ülkelerde ise kamunun eğitim harcamalarının GSYH içindeki payı arttıkça üniversiteye katılım oranı negatif etkilenmektedir. Dolayısıyla yükseköğretime kayıt düzeyi konusunda üst sıralarda yer alan ülkelerin kamu kaynaklarını üniversiteler yerine mesleki eğitime yönlendirmelerinin kalkınma hedeflerine daha fazla katkı yapacağı düşünülmektedir.
Capacity development training workshop on crop simulation modelling and effects of climate risks on agricultural production systems in Southeast Asia
Authors: Geetha Mohan , Hoogenboom Gerrit , Jintrawet Attachai , Buddhaboon Chitnucha , Anothai Jakarat
Published: September 2024

Southeast Asia (SEA) has experienced frequent floods and droughts, posing severe challenges for farmers, agricultural scientists and extension officers. Consequently, crop modelling has become imperative in developing agricultural production systems and making informed decisions at the field level. The Decision Support System for Agrotechnology Transfer (DSSAT) can be effectively utilised at both farm and regional levels to assess the influence of climate change on production across different spatial scales. Moreover, it supports planning adaptation strategies tailored to the needs of farmers. The one-week hands-on training workshop aims to enhance technical and scientific proficiency in crop simulation modelling and evaluate the effects of climate risks on agricultural production systems in Southeast Asian countries such as Cambodia, Lao PDR, Thailand and Vietnam. A total of 62 participants from the selected countries, including Singapore and Ethiopia, were joined in the training. Among them were 48 male and 24 female individuals, comprising researchers, students, scientists, academicians and extension officers. The participants predominantly acquired knowledge of crop simulation modelling techniques by utilising existing case examples and lecture materials from the DSSAT foundation. Furthermore, the training workshops establish research networks and collaborations among the participant countries, facilitating the exchange of scientific knowledge related to innovative farm management practices and fostering interactions between local agricultural communities and scientists.
The Midterm Outcomes of Endovascular Therapy for Femoropopliteal Lesions via Drug-Coated Balloon, Directional Atherectomy and Bare Metal Stent Angioplasty
Authors: Lin Yuhao , Quan Jianjun , Dong Jian , Cong Longlong , Yang Lin
Published: September 2024

Background: This study investigated the midterm primary patency of drug-coated balloons (DCBs), directional atherectomy plus balloon angioplasty (DA), and bare metal stent (BMS) angioplasty for the treatment of femoropopliteal lesions. Methods: This two-center retrospective cohort study included 105 patients (110 limbs) undergoing DCB, DA, and BMS angioplasty—32 patients (34 limbs), 31 patients (32 limbs), and 42 patients (44 limbs), respectively. The demographic, baseline, and procedure data were collected, and the complications and midterm outcomes (patency, amputation-free survival, and clinically driven target lesion revascularization rates) were analyzed. Results: All three procedures achieved a 100% success rate. Significant improvements were noted in ankle brachial index, walking distance, and Rutherford classification at 30 days post-procedure (p < 0.001), with no differences or severe complications among the groups. The all-cause mortality rate during the follow-up period, was 5.5%, and amputation-free survival rates at 24 months were 97.0%, 90.6% and 90.9% in the DCB, DA, and BMS angioplasty groups, respectively. The primary patency rate for the DCB group (79.4%) exceeded those of the DA (56.2%) and BMS (52.2%) groups (p < 0.05), with no significant difference between the DA and BMS groups at 24 months. The secondary patency and clinically driven target lesion revascularization rates were similar among the three groups. A runoff number ≤1, Trans-Atlantic Intersociety Consensus (TASC) D, and severe calcification were found to be independent risk factors for primary patency. Conclusions: The DCB procedure demonstrated superior primary patency, compared to both BMS and DA procedures, in the treatment of femoropopliteal lesions.
“Pepe” ile “Maysa ve Bulut” Adlı Yerli Çizgi Filmlerdeki Folklorik Unsurların İncelenmesi
Authors: Alataş Ayfer
Published: September 2024

Folklor, geçmişin kültürel değerlerinin gelecek nesillere aktarılarak yaşatıldığı maddi ve manevi unsurların tümüdür. Temel insani değerlerin ve kültürel yapının ‘çocukluk’ adı verilen süreçte şekillenmesi, kültürel kodların bu süreçte çocuklara aktarılmasını değerli kılmıştır. Çalışmada, geçmişini bilen kişilerin geleceğe hükmetmesi gerçeğinden ve amacından hareketle TRT çocuk kanalında yer alan “Maysa ve Bulut” ile “Pepe” çizgi filmleri çalışmamızın konusu olmuştur. İçerik analizi yöntemi ile çalışmaya konu olan çizgi filmlerden “Maysa ve Bulut” 30 bölüm ve “Pepe” 45 bölüm olarak incelenmiştir. Söz konusu çizgi filmlerde içerik analizi yöntemi kullanılarak folklorik unsurların neler olduğu ve bunların nasıl temsil edildiği üzerine anlam okumaları yapılmıştır. Araştırılması amaçlanan olgu hakkındaki bilgi içeren film, video gibi elektronik kaynaklar ve yazılı materyaller incelenmiştir. Çocuğun büyüme ve bireyselleşme sürecinde önemli bir yeri olan çizgi filmler tahlil edilerek kültürel kodları ne kadar barındırdığı tespit edilmiştir. Adı geçen çizgi filmlerin çocukların ilgi, ihtiyaç ve meraklarını karşılayarak folklorik öğeleri ve kültürel kodları barındırması yönüyle bilimsel ve nesnel bakış yöntemiyle değerlendirilmiştir. Atalardan kalan kültürel mirasın varlığını devam ettirebilmesi, bir milletin var olabilmesi için önemlidir. Çizgi filmler, kültürel kodları aktarması yönüyle çocukların gelişimlerine katkı sağlamakta olup tespit edilen sembollerin tahlili bu önemi ortaya koyacaktır. Bu değerlendirmenin sonunda söz konusu çizgi filmlerin Türk folklor ögelerini farklı boyutta temsil ettiği sonucuna ulaşılmıştır. Anneye –babaya ve büyüklere saygı, yeme içme adabı gibi olumlu davranışların yanı sıra çocuğa küsüp yemek yememe, hasta numarası yapıp okula gitmeme gibi olumsuz davranışları da kazandırdığı tespit edilmiştir.
Guidelines for equipment and support for endoscopic examinations (part one)
Authors: Starkov Yu. G. , Korolev M. P. , Starodubov V. I. , Balalykin A. S. , Ivantsova M. A. , Nikonov E. L. , Veselov V. V. , Fedorov E. D. , Khrustaleva M. V. , Belova G. V. , Duvansky V. A. , Shcherbakov P. L. , Korzheva I. Yu. , Ivanova E. V. , Olevskaya E. R. , Timofeev M. E. , Shishin K. V. , Budzinsky S. A. , Solodinina E. N. , Karpenkova V. I. , Grenkova T. A. , Sivokozov I. V. , Vasilyev I. V. , Dzhantukhanova S. V. , Zamolodchikov R. D. , Kuvaev R. O. , Voroshin D. G. , Veselov A. V. , Kulaev K. I. , Primasyuk O. P. , Ilyashenko M. G. , Vagapov A. I. , Khain V. V. , Gnevashev S. A. , Kazak S. M. , Ivantsov Yu. V. , Alkhanov E. V.
Published: September 2024

The guidelines describe modern approaches to equipping and ensuring endoscopic examinations of the digestive and respiratory systems in accordance with the objectives of improving their quality, safety and efficiency. The focus is on improving endoscopic diagnostics of precancerous diseases and early cancer of the gastrointestinal tract and bronchi. Based on the analysis of evidence-based medicine data, modern conditions for equipping and ensuring endoscopic examinations from the minimum necessary to the expert level are provided, including conditions for integrating digital solutions into protocols and reports, including conditions for creating databases for artificial intelligence systems, as well as conditions for ensuring epidemiological safety in endoscopy. The guidelines are based on risk-oriented approaches and serve as a basis for an objective assessment and analysis of the risks of compliance of equipment and provision in endoscopy with modern requirements for the quality and safety of medical activities. The components of equipment and provision are presented in summary tables, which in practice can serve as checklists. Each component is also an evaluation parameter and can be assessed by qualitative (present or absent) and/or quantitative (% provision) indicators. The methodological recommendations are designed in accordance with the requirements of the current GOST R 6.30-2003: “Unified documentation systems. Unified system of organizational and administrative documentation. Requirements for the execution of documents” (updated on 05/25/2017), which states that this type of methodological product, based on positive experience, reveals the order and logic of setting up any methodology. The objectives of such documents include the promotion of the most effective and rational examples of practical actions applicable to a certain type of activity, according to which the terminology, style and volume of methodological recommendations are regulated.
Can Experience Sampling Self-monitoring tools promote the activation of clients in mental healthcare? A qualitative study
Authors: de Thurah Lena , Weermeijer Jeroen Dennis, Merlijn , Uyttebroek Lotte , Wampers Martien , Bonnier Rafaël , Myin-Germeys Inez , Kiekens Glenn
Published: September 2024

BACKGROUND: Actively engaging clients in managing their health and care is crucial for person-centered mental healthcare. Self-monitoring tools such as the Experience Sampling Method (ESM) can help individuals collect information about their mental health and daily activities on their smartphones and share this with their clinicians.AIMS: This qualitative paper examines whether and how ESM self-monitoring might enhance self-insight, self-management, self-efficacy, therapeutic alliance, and shared decision-making and this way promote the activation of clients in mental healthcare. METHODS: Twelve clinicians and 24 clients participated in the IMPROVE study. After using the IMPROVE ESM self-monitoring tool, seven clinicians and 11 clients were interviewed and a thematic analysis examined participants' experiences of changes in client activation. RESULTS: Clients reported improvements in self-awareness, self-insight, and self-management. Only a few participants experienced enhanced self-efficacy, improved therapeutic alliances, and more client involvement. Self-awareness was mainly boosted via smartphone self-monitoring, while collaborative data interpretation between clients and clinicians was crucial for unlocking insights about clients' mental health and creating actionable therapy goals.CONCLUSION: Our findings suggest that using ESM self-monitoring tools can help enhance the activation of clients in mental healthcare. Future research should develop best practice guidelines for integrating these tools into clinical care.
Phase confusion: how inconsistent cardiac labelling obscures interoception research
Authors: Caparco Angelia , Lopez-Martin Genaro , Galvez-Pol Alejandro
Published: September 2024

Research on the interaction between interoception and external sensory processing has grown rapidly, with a key focus on how different phases of the cardiac cycle (systole and diastole) affect stimulus processing. This typically involves synchronizing stimulus presentation with specific cardiac phases. However, the definition of these phases varies significantly across studies. As in biomedical disciplines, some studies define systole as the period from the R-peak to the end of the T-wave in the electrocardiogram (ECG), with diastole encompassing the rest of the cycle. Others use a time-based heuristic approach, defining systole based on the estimated time for afferent signals from the heart to reach the brain. These studies assume that baroreceptor activity near the heart plays a key role in cognition, though conclusive evidence for this assumption is lacking. This variation in definitions has led to a confusing characterization of cardiac phases, where systole in one study may correspond to diastole in another (and vice versa). To address this, we review current research on how cardiac phases affect external stimulus processing and highlight methodological inconsistencies in their operationalization. We debate the use of time-based heuristic approaches and discuss additional sources of variability, such as differences in recording equipment and measures of interoceptive abilities. Rather than focusing on specific study findings, we emphasize the broader challenges posed by these inconsistencies, including issues with replicability and interpretation. Finally, we provide recommendations for standardizing methodologies to improve the reliability and comparability of future research.
Canadian Dietary Intakes Assessed by Nutrient Profiling Models and Association with Mortality and Cardiovascular Disease
Authors: Jacobs Adelia C. , Jessri Mahsa
Published: September 2024

Purpose: Nutrient profiling (NP) ranks foods according to nutritional composition and underpins policies (e.g., front-of-package (FOP) labelling). This study aimed to evaluate Canadian adults’ dietary intakes using proposed Canadian FOP “high-in” labelling thresholds and international NP models (i.e., Ofcom, FSANZ, and Nutri-Score) and examine the association between intakes using international NP models and all-cause mortality and cardiovascular disease (CVD).

Methods: Intakes from the Canadian Community Health Survey-Nutrition (CCHS-Nutrition) 2004 and 2015 were given NP scores and assessed against FOP thresholds. CCHS-Nutrition 2004 was linked with death records (Canadian Vital Statistics Database, n = 6767) and CVD incidence and mortality (hospital Discharge Abstract Database, n = 6420) until December 2017.

Results: Foods that would require FOP labels, should there be such regulation in Canada, contributed 38% of calories. Association between NP scores and mortality was significant for Ofcom, FSANZ, and Nutri-Score (hazard ratio (HR) in highest quintile (lowest quality): 1.73, 95%CI [1.20–2.49], 1.59[1.15–2.21], and 1.75[1.18–2.59], respectively), and for CVD incidence, among males (HR in highest quintile: 2.11[1.15–3.89], 1.74[1.07–2.84], and 2.29[1.24–4.24], respectively).

Conclusions: Canadians had moderately healthy intakes. NP systems could discriminate between low and high dietary quality such that adults with the lowest diet quality were more likely to experience all-cause mortality and CVD events (for males).
Estrategias de Marketing Digital y Presencia en Redes Sociales para el Posicionamiento de las MIPYMES en Ecuador
Authors: Zambrano Verdesoto German Jazmany
Published: September 2024

Introducción:  En un entorno empresarial cada vez más competitivo, las micro, pequeñas y medianas empresas en Ecuador buscan estrategias efectivas para mejorar su posicionamiento en el mercado.Metodología: Se realizó un revisión bibliografica para fundamentar  las variables de investigación, tambien se realizaron 312 encuestas a clientes de MiPymes los datos recopilados fueron analizados mediante un modelo de ecuaciones estructurales (SEM), una técnica estadística que permite evaluar las relaciones entre múltiples variables. Resultados: Se identificó que las estrategias de marketing digital tienen un impacto significativo en la presencia en redes sociales de las MiPymes  y también  que  una mayor presencia en redes sociales influye positivamente en el posicionamiento de la marca. Discusión: La presencia activa en  redes sociales  influye notablemente en los  clientes y es factor  diferenciador al momento de elgir una marca. Conclusiones: Las estrategias de marketing digital y la  presencia activa en redes sociales son fundamentales para el posicionamiento de la marca de las MiPymes en Ecuador. Las empresas que invierten en estas áreas pueden esperar una mejora en su reconocimiento y competitividad en el mercado.
Traditional and debate-focused flipped methodology in the teaching of “English Narrative”
Authors: Sánchez Cuervo Margarita Esther
Published: September 2024

Introduction: This research presents a practice of flipped learning for the subject of “English Narrative”, taught in the degree of Modern Languages at the University of Las Palmas de Gran Canaria. Methodology: A group of 25 students has received two variants of this methodology: traditional and debate-focused flipped classroom to study two recognised writers of English literature: Charles Dickens and E. M. Forster. Results: Dickens’s lesson has followed a traditional flipped classroom, where the group has seen a presentation about the novelist and his work made by the teacher outside class. The time spent in the face-to-face session has been devoted to doing specific exercises and deepening into the author’s style. Forster’s lesson has applied a debate-focused flipped learning, where the group has also seen a similar presentation. The questions are oriented towards the contrast of ideas to generate a discussion in class that favours the exchange of opinions. Discussion: The evaluation of this experience has been performed by means of questionnaires in which the methodology of flipped learning has been preferred over the more traditional one, even though the latter is largely valued. Conclusions: The students’ suggestions will be considered when applying this methodology to most authors of “English Narrative”.
MODELAGEM MATEMÁTICA E CINÉTICA DE SECAGEM DE SEMENTES DE ABÓBORA
Authors: Leal Barros Sâmela , Melo Frota Maryana , Pessoa Melo Mylena Olga , Alves dos Santos Isabela , Barros de Vasconcelos Lucicleia
Published: September 2024

A abóbora possui uma importância socioeconômica que gira em torno do seu cultivo e, consequentemente, da sua comercialização. Durante o processamento, as sementes encontradas no interior do vegetal são descartadas, no entanto, são fontes de ácidos graxos e proteínas. Para a sua comercialização é necessário processos de secagem que preservem as qualidades físicas e nutricionais durante o armazenamento. Nessa perspectiva, o presente estudo teve o objetivo de ajustar diferentes modelos matemáticos aos valores experimentais da secagem de sementes de abóbora (Cucurbita máxima) e avaliar quais dos modelos melhor representa o fenômeno. A cinética de secagem das sementes foi realizada em estufa com circulação de ar, nas seguintes temperaturas: 50, 60 e 70°C. Aos dados experimentais foram ajustados três modelos empíricos, Page, Midilli e Henderson&Pabis, avaliados quanto a magnitude do coeficiente de determinação (R2) e do desvio quadrático médio (DQM) por meio do Software STATISTICA 12, utilizando a análise de regressão não-linear, pelo método Quasi-Newton. O modelo de Midilli foi o que apresentou maiores valores de R2 e valores inferiores de DQM em comparação aos demais modelos, mostrando maior confiabilidade em representar o fenômeno de secagem de sementes de abóbora. O modelo de Henderson e Pabis apresentou uma distribuição tendenciosa de resíduos, indicando que não se adequa ao fenômeno estudado. Os tempos de secagem variaram de 450 a 600 min. A maior temperatura estudada favoreceu a transferência de massa das sementes e reduziu o teor de umidade de equilíbrio dinâmico e o tempo de secagem. Percebeu-se a proporcionalidade dos parâmetros “a” e o “k” com a temperatura do ar de secagem, contudo, o parâmetro “b” sofreu diminuição com o acréscimo da temperatura. O parâmetro “n”, não apresentou influência das temperaturas utilizadas.
AVALIAÇÃO DAS CARACTERÍSTICAS FÍSICO-QUÍMICAS DE BORRAS DE CAFÉS ESPECIAIS ORGÂNICAS E NÃO ORGÂNICAS EXTRAÍDAS EM FILTRO KOAR
Authors: Oliveira Marisa , Lima Costa Donato Maria Vitória , Wagner Vilela Santos Wallysson , Daniel Santos Silva Gustavo Henrique , Pedroza Suzana
Published: September 2024

A borra do café é um resíduo sólido composto por uma combinação de grãos moídos, óleos essenciais, compostos solúveis e insolúveis que não foram completamente extraídos durante a infusão da bebida e, categorizada em dois tipos diferentes: orgânica e não-orgânica. Quando descartada de maneira inadequada, a borra de café pode contribuir para poluição do meio ambiente, entretanto, pode ser utilizada de várias maneiras, seja elas: promovendo a reciclagem de nutrientes, promovendo a melhoria do solo, agindo como repelente para pragas, utilização na indústria cosmética, matéria-prima para produção de biodiesel, causando impactos socioeconômicos e ambientais positivos. O objetivo do presente estudo foi caracterizar física e físico-quimicamente as borras de café orgânicas e não-orgânicas cedidas por uma cafeteria da cidade de Garanhuns, Pernambuco, assim como seus benefícios, males e importância para futuros estudos em áreas diferentes da agroindústria. Foram realizadas análises físico-químicas nas borras, incluindo umidade, cinzas, lipídios, proteínas, atividade de água, pH, condutividade, acidez total titulável, sólidos solúveis totais, cor, açúcares redutores e cafeína. Os resultados mostraram diferenças significativas entre as borras orgânicas e não-orgânicas em relação aos diversos parâmetros. Concluindo-se, que através da metodologia e análises empregadas, foi possível relacionar os resultados obtidos para borras de café orgânicas e não orgânicas, onde os parâmetros de umidade, atividade de água, pH, condutividade elétrica, sólidos solúveis totais e cor apresentaram diferença significativa., apresentando semelhanças em relação à quantidade de compostos inorgânicos, teores lipídico e proteico, acidez, açúcares e cafeína. Sendo importante investir em pesquisa e inovação sobre os resíduos gerados no processamento pós-colheita e no pós-extração da bebida café, a fim de que os produtores, baristas e consumidores de café tornem-se mais informados e definam a forma mais sustentável, viável e eficiente deste subproduto.
Study of the anisotropy of α-33S single crystal thermal expansion
Authors: Serebrennikova P. S. , Panchenko A. V. , Egorov N. В. , Gromilov S. А.
Published: September 2024

A technique for arbitrary symmetry crystals unit cell parameters refining on modern single-crystal diffractometers is described. The technique is based on the 2D detector position calibration. The elementary orthorhombic unit cell parameters of the α-33S single crystal have been refined. The anisotropy of parameters changes in the range of 90–350 K has been studied. It is shown that the relative increase in parameter c is 6.4%. The obtained dependences are approximated by second–third degree polynomials. The absolute increase in cell volume is 138.4 A3, and the relative increase is 4.3%. The temperature dependencies of the thermal expansion tensor elements has been refined. The coefficients of α-33S thermal expansion tensor at the room temperature are: α11 = 15.35 × 10–5, α22 = 8.56 × 10–5, α33 = 9.12 × 10–5 К–1.
Morphology and spatial distribution of ordered domains in GaInP/GaAs(001) according to transmission electron microscopy
Authors: Myasoedov А. V. , Bert N. A. , Kalyuzhnyy N. А. , Mintairov A. M.
Published: September 2024

The structure of epitaxial films of the GaInP solid solution, in which ordering occurs, was studied using transmission electron microscopy. The films were grown by metalorganic vapor phase epitaxy on GaAs (001) substrates near the half-composition point. During the study, dark-field images obtained using superstructure reflections for cross-sectional and plan-view specimens of films were analyzed. The morphology and relative spatial arrangement of ordered domains have been determined. The phenomenon of spontaneous self-organization of regions with CuPt–B+ and CuPt–B– ordering near the surface was discovered, while in the bulk of the film the domains are uniformly located and mutually overlap each other. The effect of spatial separation of domains is associated with the lattice relaxation, leading to a change in the surface topology.
Microfluidic-assisted synthesis of hybrid calcium carbonate/silver microparticles
Authors: Ermakov А. V. , Chapek S. V. , Lengert Е. V. , Konarev P. V. , Volkov V. V. , Soldatov M. A. , Trushina D. B.
Published: September 2024

The development of advanced methods for the synthesis of nano- and microparticles for biomedical applications is of considerable interest. A method for the synthesis of submicron silver-shelled calcium carbonate particles using a microfluidic chip designed to provide control over particle formation is proposed. Precise control of reaction parameters enables the formation of silver shell and calcium carbonate particles in a controlled manner. The distribution of pores in the hybrid particles was analyzed using small-angle X-ray scattering, which provided insight into the complex structure of the pores. The results provide information on particle morphology and may facilitate the development of new calcium carbonate-based materials for various applications.
The Similarity of Quasi-geostrophic Vortices Against the Background of Large-Scale Barotropic Currents
Authors: Zhmur V. V.
Published: September 2024

The paper proposes a theory of similarity of quasi-geostrophic vortices against the background of large-scale flows. This information is useful when planning laboratory and numerical experiments to study mesoscale and submesoscale vortex dynamics of vortices interacting with currents. Special attention is paid to the study of geometric similarity of phenomena. It is revealed that the complete set of dimensionless similarity numbers of baroclinic vortices includes four dimensionless parameters: the dimensionless intensity of the vortex, the geometric similarity of the background flow (the ratio of relative vorticity to the deformation coefficient of the background flow), the coefficient of horizontal elongation of the vortex core and the coefficient of vertical oblateness of the vortex core coinciding with the Burger number. To describe the similarity of barotropic vortices against the background of barotropic flows, the number of necessary dimensionless parameters is reduced by one number — the coefficient of vertical oblateness of the vortex core is eliminated from consideration. When studying axisymmetric vortices or vortex structures close to axisymmetric, another geometric parameter of the vortex is eliminated from consideration — the coefficient of horizontal elongation of the vortex core. As a result, the maximum possible set of similarity parameters includes four dimensionless numbers, and the minimum is two.
Organic Carbon Content in Dissolved and Particulated Forms in the Kara Sea Water
Authors: Belyaev N. A. , Fedulov V. Yu. , Kravchishina M. D. , Shchuka S. A.
Published: September 2024

Data of suspended matter content, concentrations of dissolved and particulate organic carbon in the Kara Sea water for 2007-2022 are summarized. A difference in the distributions of dissolved (DOC) and particulate (POC) organic carbon in the water column during the autumn (September) and spring-summer (July-August) periods was revealed. An increase of concentrations of dissolved organic carbon was recorded both on the surface and in the water column in the summer. Analysis of the dependences of DOC concentrations on salinity showed that the increase in these concentrations is not associated with an increase in DOC concentrations in river runoff waters. There was also a significant increase in DOC and POC concentrations in phytoplankton bloom zones throughout the water column. Thus, a connection has been identified between seasonal increases of organic matter concentrations in the open part of the sea and the processes of phytoplankton blooming.
Air quality index prediction for clearer skies using improved long short-term memory
Authors: Bahadure Nilesh Bhaskarrao , Sahare Oshin , Shukla Nishant , Mandal Rohit , Pandey Pramod , Patni Jagdish Chandra , Mohiddin Md. Khaja
Published: September 2024

Air pollution has become an international calamity, a problem for human health and the environment. The ability to predict the air quality becomes a crucial task. The usual approaches for assessing air quality are exhausted when extracting complicated non-linear relationships and long-term dependence features embedded in the data. Long- and short-term memory, a recurrent neural network family, has emerged as a potent tool for addressing the mentioned issues, so computer-aided technology has become essential to aid with a high level of prediction and best-in-class accuracy. In this study, we investigated classic time-series analysis based on Improved Long short-term memory (ILSTM) to improve the performance of air quality index prediction. The predicted AQI value for the 25 days lies in a 97.63% Confidence interval zone and highly adoptable performance metrics such as R-Square, MSE, RMSE, and MAE values.
Modulation of Cerebellar Oscillations with Subthalamic Stimulation in Patients with Parkinson’s Disease
Authors: Bosch Taylor J. , Cole Rachel C. , Vuong Shawn M. , Flouty Oliver , Singh Arun
Published: September 2024

Background:

Deep brain stimulation (DBS) targeting the subthalamic nucleus (STN) has emerged as a potent treatment for alleviating motor symptoms in Parkinson’s disease (PD). Despite its effectiveness, the impact of high frequency STN-DBS on cerebellar oscillations remains unclear, posing an intriguing challenge for neural modulation. Given the direct and indirect connections between the STN and cerebellum, we investigated whether STN-DBS affects cerebellar oscillations.

Objective:

To observe the effects of STN-DBS on cerebellar oscillations in patients with PD.

Methods:

We recruited 15 PD patients receiving STN-DBS. Electroencephalographic (EEG) signals were recorded from cerebellar regions during resting-state conditions in both the OFF-DBS and STN-DBS conditions. Our analyses centered on spectral features, particularly theta and beta oscillations, guided by prior research and correlation tests to investigate the relationship between oscillatory changes and motor symptom severity.

Results:

In the mid-cerebellar (Cbz) region, we observed a significant increase in the relative power in all frequency bands, including theta and beta oscillations during STN-DBS, showing the global effect of DBS. Importantly, the correlation results indicated significant associations between mid-cerebellar (Cbz) beta power during the OFF condition and motor severity, which were not evident during STN-DBS. Interestingly, correlations between beta power and motor severity were not observed at the mid-occipital (Oz) and mid-frontal (Cz) regions. Notably, signal similarity analyses demonstrated no evidence of volume conduction effects between the mid-cerebellar (Cbz) and nearby mid-occipital (Oz) regions.

Conclusions:

While these findings provide valuable insights into the complex interplay between STN-DBS and neural oscillations, further research is essential to decipher their precise functional significance and clinical implications. Understanding these intricacies may contribute to the optimization of DBS therapies for PD.
Infections in the Etiology of Parkinson’s Disease and Synucleinopathies: A Renewed Perspective, Mechanistic Insights, and Therapeutic Implications
Authors: Mercado Gabriela , Kaeufer Christopher , Richter Franziska , Peelaerts Wouter
Published: September 2024

Increasing evidence suggests a potential role for infectious pathogens in the etiology of synucleinopathies, a group of age-related neurodegenerative disorders including Parkinson’s disease (PD), multiple system atrophy and dementia with Lewy bodies. In this review, we discuss the link between infections and synucleinopathies from a historical perspective, present emerging evidence that supports this link, and address current research challenges with a focus on neuroinflammation. Infectious pathogens can elicit a neuroinflammatory response and modulate genetic risk in PD and related synucleinopathies. The mechanisms of how infections might be linked with synucleinopathies as well as the overlap between the immune cellular pathways affected by virulent pathogens and disease-related genetic risk factors are discussed. Here, an important role for α-synuclein in the immune response against infections is emerging. Critical methodological and knowledge gaps are addressed, and we provide new future perspectives on how to address these gaps. Understanding how infections and neuroinflammation influence synucleinopathies will be essential for the development of early diagnostic tools and novel therapies.
Microbial community composition in subgingival plaques and heterogeneity of tumor tissue TCRβ CDR3 repertoire in patients with moderate-to-severe periodontitis and oral squamous cell carcinoma
Authors: Huang Jie , Yang Kun , Gao Li , He Quanmin , Ge Song
Published: September 2024

BACKGROUND:

The human oral cavity contains over 700 types of bacteria that may protect the body against colonization by exogenous pathogens and maintain relative homeostasis. However, alterations in the immune status can disrupt the balance between microorganisms and the host, inducing various diseases such as oral cancer and diabetes mellitus. The mechanism underlying this process is not clearly understood.

OBJECTIVE:

The purpose of this study was to investigate the relationships between subgingival bacteria, T-cell receptor [Formula: see text]-chain complementarity-determining region 3 (TCR[Formula: see text] CDR3), and the development oforal squamous cell carcinoma (OSCC).

METHODS:

We grouped patients as “healthy periodontal” (H), “moderate-to-severe chronic periodontitis” (C), and “moderate-to-severe chronic periodontitis with OSCC” (T). Bacterial groups were “subgingival plaque” (bp) and “gingival/tumor tissue” (g). We also recorded patients’ age, gender, attachment level (AL), bleeding on probing (BOP), and probing depth (PD). We extracted and sequenced RNA from plaques, gingival tissues, tumors, and teeth. We performed high-throughput sequencing on TCR[Formula: see text] CDR3 and plaque bacteria.

RESULTS:

Synergistetes and Veillonella parvula were more abundant in the H group than in the T group. Granulicatella, Peptostreptococcus, and Streptococcus infantis were enriched in the T-bp group. AL, BOP, and PD were positively correlated with Granulicatella, Peptostreptococcus, and Pseudomonas but negatively correlated with Prevotella nigrescens and V. parvula. TCR[Formula: see text] CDR3 diversity was C [Formula: see text] H [Formula: see text] T. TCR [Formula: see text]-chain Variable gene (TRBV)20-1 usage varied among the H, C, and T groups. TRBV2 and TRBV5-1 usage was greater in the T group than in the C group. TRBJ1-1, TRBJ1-2, TRBJ2-2, TRBJ2-7, and TRBJ2-5 were most frequently used.

CONCLUSIONS:

These trends and the reduction of gingival Synergistetes were correlated with OSCC. TCR[Formula: see text] CDR3 diversity was the lowest in patients in the T group, and there were considerable changes in the expression of TRBV2 and TRBJ. Therefore, plaque bacterial composition can influence TCR[Formula: see text] CDR3.
Arterial variations and hemodynamic impact in the upper limb: Insights from an observational study
Authors: Chen Xin , Yu Zhengya , Wu Jixiang
Published: September 2024

BACKGROUND:

The incidence of arterial variations in the upper limb is variable among ethnic groups. However, there are only a few studies on the Asian population, particularly in China.

OBJECTIVE:

This research provided the first large data series on arterial variations in the upper limb of Chinese adults.

METHODS:

In this observational study, the arteries in the upper limb of consecutive patients were analyzed between July 2020 and June 2021, and the hemodynamic variables of each patient were collected.

RESULTS:

The brachial artery deviated in 6.60% of upper limbs (11.89% of patients), and the brachioradial artery (BRA) was the most frequent variation. In the wrists of all patients, the volume flow (VF) of the BRA was lower than that of the radial artery (RA). Besides, the VF of the BRA in patients with end-stage renal disease (ESRD) was lower than that in those without ESRD in the wrist. Additionally, in the forearms of patients without ESRD, the VF of the BRA was lower than that of the RA. In the upper arm of patients with ESRD, the VF of the brachial artery in patients with BRA was significantly lower than that in patients with RA.

CONCLUSION:

The incidence of arterial variations in the upper limb of Chinese adults was 6.60% (limbs) or 11.89% (patients) in this study. In our investigation, the BRA was the most common high bifurcation of the brachial artery type. Furthermore, the Chi-squared test revealed significant differences in the distribution, which was common in the right upper limb but not in sex.
Families and problems of Vietnamese families in the process of international integration
Authors:   Ho Chi Minh City University of Technology, VNUHCM, Dang Diem Kieu
Published: September 2024

The process of international integration has multidimensional impacts on various aspects of social life, changing human perceptions in relationships, especially in marital and family relationships. Nowadays, along with the dynamics of the market economy, industrialization, modernization, and international integration, there have been certain impacts on changes in family life, both positive and negative. The process of international integration has brought about significant changes in many areas of Vietnamese society, especially as the country continues to open up to the global market, its economy, culture, and social norms are influenced by external factors. One of the areas most affected is family life. These changes are not only due to the influence of Western values but also due to exposure to different lifestyles and family models from other Asian countries, including China, South Korea, and Japan. These changes are evident in the marriage evaluation, gender roles, and parenting in Vietnamese families. More specifically, younger generations emphasize individualism and freedom of choice in relationships. Therefore, identifying the impact of the international integration process on Vietnamese families to promptly propose directions and solutions to promote the positive aspects and limit the negative ones is both urgent and long-term issue.
Peran Kualitas Integrasi Omnichannel dalam Membentuk Niat Perilaku Generasi Y & Z
Authors: Agung Deatri Arumsari , Purwanto Gabriella Lisbeth Avriel , Ellitan Lena
Published: September 2024

This research aims to understand the omnichannel shopping behavior of the Y and Z generations, by focusing on the role of customer involvement in mediating the influence of omnichannel integration quality on behavioral intentions, and examining the role of age in moderating the influence of customer involvement. This quantitative research uses a Likert scale, where the total number of questionnaires obtained and processed was 204 samples. This research was conducted in Surabaya with respondents from Surabaya and its surroundings. Data analysis was carried out using PLS-SEM technique, with the SmartPLS3 analysis tool. The three dimensions of omnichannel integration quality, namely channel-service configuration, integrated interactions, and assurance quality, are proven to have a positive influence on customer engagement. Customer involvement is proven to influence behavioral intentions positively, and mediate the influence of omnichannel integration quality three dimensions on behavioral intentions. Age is also proven to have a moderating role that strengthens the influence of customer involvement on behavioral intentions. One managerial implication is that generation Y should be of greater concern in efforts to develop customer engagement, compared to generation Z, to maximize customers' behavioral intentions.
Severe, uncontrolled epilepsy in pregnancy: A population-based case-control study
Authors: Kemp Bryn , Kelso Andrew , Williams David , Knight Marian
Published: September 2024

Background Epilepsy affects one percent of the UK population and is the most common serious neurological condition experienced during pregnancy. We compared the characteristics, clinical management, and pregnancy outcomes in women with severe, uncontrolled epilepsy to those of women with well controlled disease. Methods We conducted a population-based case-control study in all UK consultant-led maternity units. Cases of severe uncontrolled epilepsy during pregnancy were identified prospectively and reported via the UK Obstetric Surveillance System (UKOSS). Severe epilepsy was defined a-priori as ≥1 of the following: admission to hospital during pregnancy to manage seizures; prescribed ≥3 antiepileptic medications; or died from epilepsy. Controls comprised women with epilepsy not meeting the case definition, identified within the same centres as cases. Pre-pregnancy epilepsy control and pregnancy outcomes were compared between groups using multivariable logistic regression. Results We identified 94 cases between 1 October 2015 and 31 March 2017 and compared these with 186 controls. Cases were significantly more likely to be admitted to manage seizures in the year preceding pregnancy (42/94 cases vs 10/186 controls, adjusted odds ratio [aOR]=7.38 [95% CI 2.70-20.2]), and to report their most recent seizure within 3 months of pregnancy (51/94 cases vs 18/186 controls, aOR=5.86 [95% CI 2.30-15.0]). Cases were significantly more likely to deliver before 37 weeks (20/94 cases vs 8/186 controls, aOR=7.61 [95% CI 2.87-20.2]). Conclusions Women admitted for seizure management in the year before pregnancy are at higher risk of severe epilepsy during pregnancy and of preterm birth. These women should be prioritised for discussion about pregnancy and contraception. When pregnant, they should be reviewed as early as possible by specialists in the management of epilepsy during pregnancy. Delivering messages about the importance of pregnancy planning and contraception to all women with epilepsy should be viewed as the responsibility of all clinicians involved their care.
Health Communication Film Implementation Strategy COVID-19-era: The Turning T.I.D.E. in HIV Multimedia Research
Authors: Ebor Megan T. , Viducich Isabella M. , Sutton Madeline Y.
Published: September 2024

Among public health and social behavioral scientists there is an emergent interest in using film-based methodologies to promote health and wellness. During the novel coronavirus disease 2019 (COVID-19), this research method, as well as other forms of research, were thwarted. This article reports on our experience of implementing an online health communication film intervention under a research design initially intended for in-person communal viewing. We investigated if the film-based intervention could enhance the uptake of therapeutic modalities first learned through a brief five week session for Black and Latine adults living with HIV. To address changes in research methods attributed to COVID-19, the T.I.D.E. implementation method includes four critical considerations: 1) T- Tenacious approach, increased level of persistence leveraging social and clinical supports, 2) I- Immediate Needs, connecting participants to needed community resources, 3) D- Dissemination Plan revamp and harness technology to share information, and 4) E- Environmental Awareness privacy protocol to strengthen trust by participants.
Origin and Affinities of the Malmberget Iron Oxide-Apatite Deposit, Northern Sweden: Insights From Magnetite Chemistry and Fe-O Isotopes
Authors: Henriksson Jens S. , Troll Valentin R. , Kooijman Ellen , Bindeman Ilya , Naeraa Tomas , Bauer Tobias E.
Published: September 2024

European iron ore production is primarily sourced from magnetite dominated iron oxide-apatite ore deposits in the northern Norrbotten ore province of northernmost Sweden. The Malmberget iron oxide-apatite deposit is at present the largest iron ore resource in Europe and is an amphibolite facies grade analogue of the world-famous Kiirunavaara iron oxide-apatite deposit. The Malmberget rock association is characterised by multiple phases of deformation, metamorphism, and alteration that resulted in a geometrically and petrologically complex deposit that is genetically ambiguous. Primary ore textures and emplacement structures of the Malmberget iron oxide-apatite deposit have largely been recrystallised during metamorphic overprinting and now comprise dominantly medium- to coarse-grained granoblastic magnetite. However, isotopic characteristics are preserved and when combined with trace element chemistry, these can be used to understand magmatic vs. hydrothermal origin of the deposit. To unravel the primary origin of the Malmberget magnetite ore, we combined magnetite trace element chemistry and Fe-O stable isotopes to investigate the massive magnetite in the Fabian-Kapten and ViRi ore bodies of the Malmberget iron oxide-apatite deposit. Trace element correlations indicate a high-temperature magmatic to a transitional high-temperature magmatic-hydrothermal origin of the Malmberget iron oxide-apatite ore deposit, with data plotting into fields of clear magmatic affinity in trace element discrimination diagrams. Fe-O data fall into established magmatic fields regardless of subsequent metamorphic modifications, underlining a dominantly (ortho-)magmatic origin of the investigated deposits. Despite an overall magmatic to magmatic-hydrothermal origin for the two ore bodies studied, Fe-O isotope equilibrium calculations of the magnetite suggest a possible temperature discrepancy between the Fabian-Kapten ore body and the ViRi ore body, the latter showing a more pronounced magmatic character. These variations in trace element contents and Fe-O isotopes can be explained by the proximity of the more magmatic signatures to the centre of the ore forming magmatic system.