bluuebunny/crossref_metadata_2025 huggingface dataset:
Vulvar Leiomyomatosis: A Diagnostic Challenge Case Report
Authors: Hasanzadeh Malihe , Moeindarbari Somayeh , Seresht Leila Mousavi , Jafarian Amir Hosein , Hamidi Anahita , Farazestanian Marjaneh
Published: January 2020

Introduction:

Vulvar leiomyomas are rare and usually misdiagnosed as Bartholin’s cyst
on initial presentation. Leiomyoma of vulva accounts for only 0.03% of all gynecological neoplasm.
Definite diagnosis is based on surgical excision of the tumor. The aim of this report is to
introduce a case of leiomyoma of the vulva which was initially misdiagnosed as Bartholin’s cyst.

Case Presentation:

We present a case of a 36-year old virgin female (BMI>30) who was referred to
the clinic with a 5-year history of left labial mass which was initially diagnosed as Bartholin’s cyst.
The mass was removed and the pathologist confirmed that the final diagnosis was vulvar leiomyoma.

Conclusion:

Vulvar leiomyoma is usually misdiagnosed with Bartholin cyst and distinguishing
between benign and malignant forms is confusing, so it is a diagnostic challenge. Surgical excision
is the treatment of choice in all smooth muscle tumors of the vulva. Continuing follow-up after
treatment is highly recommended.
Videoconferencing Psychotherapy in the Public Sector: Synthesis and Model for Implementation
Authors: Muir Samuel David , de Boer Kathleen , Thomas Neil , Seabrook Elizabeth , Nedeljkovic Maja , Meyer Denny
Published: January 2020

Background

Videoconferencing psychotherapy (VCP) is a growing practice among mental health professionals. Early adopters have predominantly been in private practice settings, and more recent adoption has occurred in larger organizations, such as the military. The implementation of VCP into larger health service providers in the public sector is an important step in reaching and helping vulnerable and at-risk individuals; however, several additional implementation challenges exist for public sector organizations.

Objective

The aim of this study was to offer an implementation model for effectively introducing VCP into public sector organizations. This model will also provide practical guidelines for planning and executing an embedded service trial to assess the effectiveness of the VCP modality once implemented.

Methods

An iterative search strategy was employed, drawing on multiple fields of research across mental health, information technology, and organizational psychology. Previous VCP implementation papers were considered in detail to provide a synthesis of the barriers, facilitators, and lessons learned from the implementation attempts in the military and other public sector settings.

Results

A model was formulated, which draws on change management for technology integration and considers the specific needs for VCP integration in larger organizations. A total of 6 phases were formulated and were further broken down into practical and measurable steps. The model explicitly considers the barriers often encountered in large organizational settings and suggests steps to increase facilitating factors.

Conclusions

Although the model proposed is time and resource intensive, it draws on a comprehensive understanding of larger organizational needs and the unique challenge that the introduction of VCP presents to such organizations.
Developing a Model to Predict Hospital Encounters for Asthma in Asthmatic Patients: Secondary Analysis
Authors: Luo Gang , He Shan , Stone Bryan L , Nkoy Flory L , Johnson Michael D
Published: January 2020

Background

As a major chronic disease, asthma causes many emergency department (ED) visits and hospitalizations each year. Predictive modeling is a key technology to prospectively identify high-risk asthmatic patients and enroll them in care management for preventive care to reduce future hospital encounters, including inpatient stays and ED visits. However, existing models for predicting hospital encounters in asthmatic patients are inaccurate. Usually, they miss over half of the patients who will incur future hospital encounters and incorrectly classify many others who will not. This makes it difficult to match the limited resources of care management to the patients who will incur future hospital encounters, increasing health care costs and degrading patient outcomes.

Objective

The goal of this study was to develop a more accurate model for predicting hospital encounters in asthmatic patients.

Methods

Secondary analysis of 334,564 data instances from Intermountain Healthcare from 2005 to 2018 was conducted to build a machine learning classification model to predict the hospital encounters for asthma in the following year in asthmatic patients. The patient cohort included all asthmatic patients who resided in Utah or Idaho and visited Intermountain Healthcare facilities during 2005 to 2018. A total of 235 candidate features were considered for model building.

Results

The model achieved an area under the receiver operating characteristic curve of 0.859 (95% CI 0.846-0.871). When the cutoff threshold for conducting binary classification was set at the top 10.00% (1926/19,256) of asthmatic patients with the highest predicted risk, the model reached an accuracy of 90.31% (17,391/19,256; 95% CI 89.86-90.70), a sensitivity of 53.7% (436/812; 95% CI 50.12-57.18), and a specificity of 91.93% (16,955/18,444; 95% CI 91.54-92.31). To steer future research on this topic, we pinpointed several potential improvements to our model.

Conclusions

Our model improves the state of the art for predicting hospital encounters for asthma in asthmatic patients. After further refinement, the model could be integrated into a decision support tool to guide asthma care management allocation.

International Registered Report Identifier (IRRID)

RR2-10.2196/resprot.5039
Development of a Short Instrument for Measuring Health-Related Quality of Life in Oncological Patients for Clinical Use: Protocol for an Observational Study (Preprint)
Authors: Schrage Theresa , Görlach Mirja , Betz Christian Stephan , Bokemeyer Carsten , Kröger Nicolaus , Mueller Volkmar , Petersen Cordula , Krüll Andreas , Schulz Holger , Bleich Christiane
Published: January 2020

BACKGROUND

Cancer patients often suffer from the physical and psychological burden of their disease and its treatment. This is frequently insufficiently identified and addressed in clinical practice. In the context of improving patient-centered care in oncological patients, patient-reported outcomes (PROs) represent an important addition to current routine care. So far, available PRO questionnaires for cancer patients are unsuitable for routine procedures due to their length and complexity.

OBJECTIVE

This study aimed to develop and psychometrically test a short questionnaire to measure health-related quality of life (HrQoL) in cancer patients for use in routine care.

METHODS

This observational study consists of two parts: (1) a qualitative study to develop a short questionnaire measuring HrQoL and (2) a quantitative study to psychometrically test this questionnaire in five oncological departments of a comprehensive cancer center. In part 1 of the study, semistructured interviews with 28 cancer patients, as well as five focus groups with 22 clinicians and nurses, were conducted to identify clinically relevant dimensions of HrQoL. The identified dimensions were complemented with related dimensions from empirical studies and reviewed via expert discussion. Based on this, a short instrument was developed. In part 2 of the study, the developed questionnaire was tested in cancer in- and outpatients at five participating oncological clinics using additional standardized questionnaires assessing HrQoL and other important PROs. The questionnaire was presented to more than 770 patients twice during treatment.

RESULTS

The project started in May 2017 with recruitment for study phase I beginning in December 2017. Recruitment for study phases I and II ended in April 2018 and February 2019, respectively. After study phase II and psychometrical analyses, the newly developed questionnaire measuring the HrQoL of all cancer entities in routine care was finalized.

CONCLUSIONS

With five to six dimensions and one item per dimension, the developed questionnaire is short enough to not disrupt routine procedures during treatment and is profound enough to inform clinicians about the patient’s HrQoL impairments and status.

CLINICALTRIAL

Open Science Framework Registries 10.17605/OSF.IO/Y7XCE; https://osf.io/y7xce/

INTERNATIONAL REGISTERED REPORT

RR1-10.2196/17854
Annotation Guideline No. 8: Annotation Guidelines for Narrative Levels
Authors: Hammond Adam
Published: January 2020

I first became aware of the SANTA project at the Digital Humanities conference

in Montreal in the summer of 2017. I had just been assigned a 90-student secondyear

undergraduate Digital Humanities undergraduate English Literature class,

set to begin in January 2018, and I was looking for a group annotation project for

my students. In previous iterations of the course, I had carried out several annotation

projects focused on the narrative phenomenon of free indirect discourse

(FID) in texts by Virginia Woolf and James Joyce. What made these projects

successful, from my perspective, was that FID is a complex phenomenon (by definition,

a passage in which it is difficult or impossible to say for certain whether a

character or narrator is speaking certain words) which is however relatively easy

to represent in machine language (for instance, with the TEI  element and

a few value-attribute pairs). The challenge in the assignment, in other words,

was literary rather than technical: while it was easy to learn the TEI tagging, it was hard to say for certain whether a passage from To the Lighthouse was in direct

discourse or FID, or to identify who exactly was speaking. To my mind,

this made the assignment a meaningful one for my students, teaching them a

technical skill while also bringing them into closer contact with the sometimesirresolvable

complexities of literary language.
Análisis comparativo de la competitividad de la producción bovina en corral en Tejupilco y Amatepec, México (2009-2014)
Authors: Hernández Martínez Juvencio , Rebollar Rebollar Alfredo , Rebollar Rebollar Samuel , Guzmán Soria Eugenio , Gómez Tenorio Germán
Published: January 2020

Se realizó un análisis comparativo de la competitividad de la producción bovina engordada en corral en Tejupilco y Amatepec, Estado de México de 2009 a 2014. La información se obtuvo de 40 productores. El cálculo de los indicadores de competitividad y de rentabilidad se realizó a través de la Matriz de Análisis de Política (MAP). Los resultados indicaron una ganancia en valores constantes por kilogramo producido de 3.22 $/kg en 2014, que fue superior en 29.3 % al obtenido en 2009; el coeficiente de rentabilidad privada pasó de 10.89 % a 12.70 %; la relación de costo privado (RCP) disminuyó de 0.51 a 0.45. Estos resultados mostraron un aumento de la competitividad por la obtención de ganancias positivas y de que la RCP en el último año fue menor en relación con el año de referencia, debido a que los precios del ganado en pie registraron una tendencia creciente que motivó a los productores a ser más eficiente en el uso de sus recursos.
Turismo rural, impacto ambiental y resiliencia en Piedra Herrada, México
Authors: Pérez Ramírez Carlos Alberto , Flores Montes Alma
Published: January 2020

Se analizó el impacto que genera el turismo rural en el ejido PiedraHerrada, ubicado en el municipio de Temascaltepec, Estadode México (México), que se caracteriza por el aprovechamientoturístico del proceso de hibernación de la mariposa monarca(Danausplexippus L.), a partir de la valoración de la resiliencia.Para ello se retoman las aportaciones de Martín-López et al.(2009) para determinar el sistema socio ecológico (SSE) del lugarde estudio, así como Strickland-Munro et al. (2010) y Santos(2012) para el análisis de los impactos del turismo en áreas naturalesprotegidas (ANP), a partir de la resiliencia y los criteriosde valoración: perturbaciones, vulnerabilidad, conectividad ypotencial de cambio. Se identificó que el turismo está generandobeneficios económicos para la población local, que a su vezincide en la conservación del entorno forestal y el hábitat de lamariposa monarca; no obstante, el SSE es sensible a la dinámicae intensificación de la actividad turística, con alcance sobre laconservación del suelo y la biodiversidad, por lo que es necesariodelinear estrategias que favorezcan la conservación ambiental y eladecuado desarrollo del turismo rural.
Influencia de valores humanos en la aceptación del queso Chapingo y sus significados intangibles de compra
Authors: Hernández Montes Arturo
Published: January 2020

La conducta de compra de las personas puede ser influenciada por valores humanos específicos y creencias individuales, entre otros factores. El propósito de la investigación fue identificar la influencia directa e indirecta de los valores humanos sobre la aceptación del queso Chapingo. Se aplicó una encuesta a una muestra (n=187) de la población estudiantil agroindustrial. Se obtuvo el coeficiente de correlación (R1) de una regresión múltiple de factores seleccionados de un análisis factorial de atributos tangibles y la aceptación; se calculó el R2 de la regresión de la aceptación y los factores seleccionados de los valores humanos, junto con residuales de atributos tangibles. Los factores de los valores y la aceptabilidad proporcionaron el R3. Adicionalmente se midieron intenciones de compra (afectivas y simbólicas). La influencia directa de los valores en la aceptación del queso se obtuvo restando R2 de R1 (cambio en R), y la indirecta resultó de la diferencia entre cambio en R y el coeficiente R3. La influencia directa no resultó significativa, demostrando que en la aceptación del queso los valores fluyeron a través de la importancia de los atributos tangibles. De los significados de compra más importantes, dos fueron afectivos y uno simbólico.
Sedación con Propofol por no anestesiólogos para colonoscopia total
Authors: Mulett-Vásquez Edelberto , Osorio Chica Mauricio , Arango Molano Lázaro Antonio
Published: January 2020

Introducción: la colonoscopia es un procedimiento de gran precisión en el diagnóstico y tratamiento de las enfermedades del colon, lo que permite visualizar la mucosa de todo el colon y el íleon terminal, si la exploración es adecuada. Clásicamente se ha utilizado ansiólisis o sedación consciente mediante la administración de benzodiacepinas o la asociación de estos fármacos y opiáceos, sin embargo, la utilización de propofol como sedante en endoscopia digestiva se ha ido extendiendo de forma paulatina en los últimos años.

Objetivo: evaluar la evolución de los procedimientos de sedación con propofol administrado por médicos no anestesiólogos en colonoscopia total.

Material y métodos: se evaluaron los pacientes programados para colonoscopia total que fueron sedados con propofol administrado por médicos no anestesiólogos, con el entrenamiento apropiado para tal fin, midiendo el comportamiento hemodinámico y respiratorio. Se excluyen los pacientes con ASA (American Society of Anesthesiologists) mayor de II.

Resultados: se en los pacientes que presentaron bradicardia fue de 1,76 mg/kg.

Conclusión: la utilización del propofol por médicos no anestesiólogos es un procedimiento que se puede considerar seguro, siempre y cuando se sigan los protocolos establecidos para tal fin evaluaron 390 pacientes, 269 (69%) mujeres y 121 (31%) hombres, con una edad promedio de 53,1 años. La dosis promedio utilizada de propofol fue de 2,3 mg/kg. El 4,9% de los pacientes presentó bradicardia según la definición utilizada. La dosis promedio de propofol.
Síndrome de Bouveret, una causa extraña de obstrucción intestinal alta: reporte de caso
Authors: Siado Guerrero Sergio Andrés , Canal Daza Fermín Alonso , Jiménez Sánchez Héctor Conrado , Martínez Montalvo Carlos Mauricio , Osorio Santos Marcela
Published: January 2020

El síndrome de Bouveret (SB) es una patología poco frecuente, la cual se caracteriza por la presencia de obstrucción gástrica o duodenal secundaria a un cálculo enclavado en la luz duodenal, el cual migra a través de una fístula colecistoduodenal. Su incidencia es de alrededor 1% al 3% de todos los casos de íleo biliar. Los principales síntomas consisten en vómito, dolor abdominal, hematemesis, pérdida de peso y anorexia. En el 91% de los casos se requiere manejo quirúrgico. En este artículo se presenta un caso de un paciente de 50 años, con cuadro clínico de 2 meses de evolución de dolor abdominal en epigastrio y mesogastrio, distensión abdominal y múltiples episodios de emesis. Al examen físico con clínica de obstrucción intestinal se realizó tomografía abdominal, donde se evidenció obstrucción intestinal por imagen intraluminal en primera porción duodenal asociada con tríada de Rigler, con diagnóstico de síndrome de Bouveret.
Investigation of Performance for Entrained Flow Gasifier Through Simulations
Authors: Rajper Suheb Ali , Unar Imran Nazir , Channa Azizullah , Bhatti Zulfiqar Ali
Published: January 2020

Pakistan has proven huge coal reserves but still unable to harvest the energy due to unavailability of ingenious technology. Coal gasification is robust, efficient and environmental friendly technology but it is highly sensitive to the coal characteristics. Scant literature is available on the development of the coal gasification technology which suits the characteristics of indigenous coal reserves. This papers presents the simulation of entrained flow gasifier for using indigenous coal through process modeling software namely Aspen Plus® to evaluate various system flow steps within an entrained flow gasifier. General techniques have also been discussed for creating the equilibrium-bases simulations of gasification systems. Peng-Robinson equation was used to correlate the volume of species with respect to state variables (temperature and pressure). The effects of composition of different indigenous coals like Thar, Lakhra and Sonda were investigated through simulations along with O/C (Oxygen-to-Carbon) ratio. Parametric study revealed that the O/C ratio along with other related system parameters have great influence on the performance. Sulfur could be available in different forms in coal like pyrite, sulfate or organic sulfur so appropriate form of sulfur in feedstocks should be corrected for better accuracy of model results. The highest percentages of CO i.e. 44.2, 37.8, and 46.6% were obtained from Thar coal (air dried form), Lakhra coal and Sonda coal respectively at the 0.3 O/C ratio. The decrease in LHV and HHV (Lower and Higher Heating Values) of syngas was observed on increase of O/C ratio for all coal types. The composition of as received Thar coal gave maximum LHV (1.5x104 KJ/Kg) and HHV (1.78x104 KJ/Kg) at the 0.3 O/C ratio. The future work could be extended by simulating biomass composition in the developed model of gasifier in transient simulations.
Exhaustive Security System Based on Face Recognition Incorporated with Number Plate Identification using Optical Character Recognition
Authors: Zaheen Muhammad Yasir , Mohi-u-din Zia , Siddique Ali Akber , Qadri Muhammad Tahir
Published: January 2020

In recent times due to rise in terrorism, people need to live in a safer place where unidentified persons will not be allowed to enter in the premises. Securing of major areas is a vital issue that needs to be addressed for the intelligence and security agencies. At the surrounding of premises, CCTV (CloseCircuit Television) cameras are usually installed to identify the number plate from database by using OCR (Optical Character Recognition) algorithm. This method of security by identifying only vehicle without verifying the person inside it is usually causing serious security issues. Identification of a person is usually done through image processing by using Viola Jones algorithm and acquire the information of the facial components to create a dataset for machine learning. It is imperative to introduce such a system that will be capable to identify the person along with the number plate of vehicle from the stored database. In this research, a comprehensive security system based on face recognition integrated with the vehicle number plate is proposed. The combined information of both dedicated cameras is then transferred to the based station for identification. This system is capable, of securing premises from crime in a more enhanced way.
Simulation Based Approach for Improving Outpatient Clinic Operations
Authors: Kalwer Muhammad Ahmed , Mari Sonia Irshad , Memon Muhammad Saad , Tanwari Anweruddin , Siddiqui Ali Arsalan
Published: January 2020

The aim of this study is to suggest the optimum number and schedule of doctors at the OPD (Out-Patient Department) of Gastrology of a hospital in Pakistan. In order to achieve this aim, the discrete event simulation model is developed to minimize waiting time of patients. Data is collected for one week from the OPD; Data collection variables are arrival and service rate of patients, their salaries/income, patient‘s OPD fee, doctor’s charges/patient, service time of patients at each of service channel i.e. reception, triage and doctors’ cabin. Stop watch is used for recording the service time of patients. Input analyzer is used to reveal the distribution of the data. Rockwell arena software version 14.5 is used to model and simulate the queuing system of the outpatient department. Scenario analysis is conducted in four scenarios; in each of the scenario doctors were assumed to be seated for one additional hour. During the period of data collection, it is observed that most of the patients are coming with an appointment of doctors therefore, it is not justified to suggest the hiring of new doctor; especially when patients are coming for the particular doctor; therefore, already available doctors are suggested to be seated longer in the OPD; that is the way to serve the maximum number of patients in the virtual queue of patients that has been kept waiting for having an appointment and for their turn to see the doctor.
Numerical Modeling and Experimental Validation in Orthogonal Machining of Aluminum Al 6061-T6 Alloy
Authors: Akram Suhail , uddin Shafi , Jaffery Syed Hussain Imran , Jalil Mian Aamir , Kazmi Syed Waqar Hyder
Published: January 2020

Non-traditional machining processes are popular for generating complex features on the work piece. With advances in material engineering, new ways of cutting technologies has been emerged. However, EDM (Electric Discharge Machining) has gained recognition for producing extraordinary surface finished, intricate part geometries with accuracy and its ability to cut through difficult to machined materials. However, like every product cycle, manufacturing processes also require energy to convert raw materials into finished product. In manufacturing operations, energy input gives carbon footprints which have an effect on our environment. It is observed that reducing energy consumption is becoming the main concern of manufacturers because of enforcing environmental laws and due to the economics of the processing. It is argued that world’s 70% of energy consumption is consumed by manufacturing sector. The aim of the work was to identify direct energy demands in wire cut EDM. The variability in energy demand was explored by operating wire cut EDM at no-load and loaded conditions.Stainless steel S304 was used as a work piece. Experiments were performed on three different wire-cut EDM.Molybdenum wire, brass wire and copper wire were used as an electrode wire and distilled water was used as a working fluid. During the experiment, electrical current was measured and the variation of power requirement was evaluated. Power required by different features of EDM was compared with the existing energy models and factors were identified that consume most of the electrical energy. Further, a comparison is made between traditional and non-traditional machining processes. This contribution will help to assess energy efficiency of EDM technology and identify priority areas for improvements. This work is also significant for machine tool designers for optimum utilization of energy,reduced environmental impact and reduced production cost of their machine tool.
Effects of different types of training on weight loss
Authors: Slavic Danijel , Karaba-Jakovljevic Dea , Zubnar Andrea , Tapavicki Borislav , Aleksandric Tijana , Drapsin Miodrag
Published: January 2020

Introduction. The difference between 24-hour daily energy intake and total
daily energy expenditure determines whether we lose or gain weight. The
resting metabolic rate is the major component of daily energy expenditure,
which depends on many different factors, but also on the level of physical
activity. The aim of the study was to determine anthropometric and metabolic
parameters of athletes engaged in different types of training, to compare
obtained results and to examine whether there are statistically significant
differences among them. Material and Methods. The study included a total of
42 young male athletes divided into two groups. The first group included 21
athletes who were predominantly engaged in aerobic type of training, and the
other group of 21 athletes in anaerobic type of training. Anthropometric
measurements were taken and resting metabolic rate was assessed using the
indirect calorimetry method. The results were statistically analyzed and the
differences in parameters between the two groups were compared. Results.
Statistically significant differences were established in total body mass,
amount of fat-free mass and muscle mass, body mass index, as well as in the
relative metabolic indices between two groups of subjects. Conclusion. The
percentage of fat-free body mass has the greatest impact on the resting
metabolic rate. The rate of metabolic activity of this body compartment is
higher in athletes engaged in aerobic than in athletes engaged in anaerobic
type of training.
Correlation between atmospheric pressure changes and incidence of abdominal aortic aneurysm ruptures
Authors: Kacanski Milos , Budinski Slavko , Markovic Vladimir , Dejanovic Bozidar
Published: January 2020

Introduction. Abdominal aortic aneurysm and its rupture have been often
studied over the years, and numerous risk factors for aneurysm rupture have
been considered, including atmospheric pressure. The effect of atmospheric
pressure has not yet been sufficiently investigated, although studies have
been conducted on its possible impact on aneurysms. The aim of this study
was to determine the presence of comorbidity as well as the impact of
atmospheric pressure on the incidence of abdominal aortic aneurysm ruptures.
Material and Methods. All patients who underwent abdominal aortic aneurysm
rupture at the Clinic of Vascular and Endovascular Surgery of the Clinical
Center of Vojvodina in the period from January 1, 2014 to December 1, 2018
were included in this study. The retrospective study was conducted using
patient medical records, computer data, additional clinical records, and
discharge reports. Data on atmospheric pressure in the territory of
Vojvodina were collected from the Republic Hydrometeorological Institute of
Serbia. Results. The number of cases with abdominal aortic aneurysm rupture
was found to be higher at higher atmospheric pressure than expected at that
altitude, in as much as 95% of cases, most often in the fall. Conclusion. We
concluded that there is a significant correlation between high atmospheric
pressure and the incidence of abdominal aortic aneurysm rupture, but the
exact mechanism of this impact remains to be studied in some further
studies.
Erratum: Hereby we offer our apologies for an inadvertent, error published in the Medical Review: 5-6/2019
Authors: Editorial E
Published: January 2020

Erratum - Hereby we offer our apologies for an inadvertent error published in
the Medical Review: 5-6/2019, on page 171 and in the contents, where Sanja
Jovanovic was listed as a co-author instead of Sandra Jovanovic. Editorial
Board

 Link to the corrected article 10.2298/MPNS1906171D
Novel PANK2 mutation identified in patient with pantothenate kinase-associated neurodegeneration
Authors: Svetel Marina , Novakovic Ivana , Tomic Svetlana , Kresojevic Nikola , Kostic Vladimir
Published: January 2020

Introduction. Pantothenate kinase-associated neurodegeneration (PKAN) is a rare, recessively inherited disorder caused by mutations in the pantothenate kinase 2 (PANK2) gene on chromosome 20p13. The objective of this report is to present a patient with atypical PKAN with the novel heterozygous PANK2 mutation. Case outline. We present a 32-year-old female who had disease onset at the age 20 (depression, speech, chewing problems and backward falls) with progressive course. Neurological examination revealed hypomimia, risus sardonicus, dysphagia, tachylalia and severe dystonic dysarthria, moderate arms, legs, and jaw-opening dystonia, postural instability, urge incontinence, and decreased visual acuity. Brain magnetic resonance imaging revealed iron accumulation in the bilateral globus pallidus and putamen (?eye-of-the-tiger?), a radiological finding pathognomonic for PKAN. Genetic analysis revealed known mutation p.T528M (c.1583C>T) in exon 6, and novel p.Y405D (c.1213T>G) in exon 3 of the PANK2 gene. In silico analyses strongly suggested this mutation to be pathogenic. Conclusion. We report a patient with PKAN, and novel substitution p.Y405D (c.1213T>G) in PANK2 that has not been previously described in PKAN patients.
Treinamento auditivo: zumbido e habilidades auditivas em idosos com perda auditiva
Authors: Bertuol Bianca , Araújo Tiago De Melo , Biaggio Eliara Pinto Vieira
Published: January 2020

Introdução: O zumbido juntamente com a perda auditiva, é uma percepção acústica anormal que pode levar a uma desorganização no Sistema Nervoso Auditivo Central. Por isso sujeitos portadores são suscetíveis ao Transtorno do Processamento Auditivo Central. O Treinamento Auditivo, baseado nos conceitos de neuroplasticidade pode auxiliar na redução do incômodo com o zumbido, por objetivar sincronia na via auditiva. Objetivo: Estimar os efeitos do Treinamento Auditivo Acusticamente Controlado Computadorizado na redução do incômodo com o zumbido e nas alterações das habilidades auditivas em idosos com perda auditiva usuários de próteses auditivas. Material e Método: Estudo transversal quantitativo e qualitativo, no qual foram reabilitados cinco idosos com zumbido, alteração em pelo menos uma habilidade auditiva e perda auditiva. Foram realizadas avaliações pré e pós intervenção, sendo elas: anamnese e avaliação audiológica básica, aplicação do questionário Tinnitus Handicap Inventory, testes comportamentais do processamento auditivo e avaliação eletrofisiológica. Realizou-se o tratamento com o software Escuta Ativa, em 16 sessões de em média 30 minutos cada. Resultados: Houve diferença estatisticamente significante em relação aos valores pré e pós tratamento no questionário Tinnitus Handicap Inventory e nos testes comportamentais. Não houve mudanças eletrofisiológicas pré e pós tratamento. Conclusão: Foi possível avaliar os efeitos do Treinamento Auditivo Acusticamente Controlado Computadorizado na redução do incômodo com o zumbido, por meio do questionário escolhido aplicado pré e pós intervenção. Além disso, algumas habilidades auditivas comportamentais também melhoraram com a referida intervenção. Apenas não foi possível observar mudanças eletrofisiológicas no Potencial Evocado Auditivo Longa Latência.
Percepção da qualidade de vida em crianças e adolescentes usuárias de próteses auditivas
Authors: Machado Renata De Quadros , Chagas Laíza Pinheiro , Pazini Eduarda , Mattiazzi Ângela Leusin , Kessler Themis Maria , Biaggio Eliara Pinto Vieira
Published: January 2020

Introdução: Com o avanço da tecnologia, os dispositivos eletrônicos relacionados com a reabilitação auditiva suprem de algum modo as necessidades dos usuários e melhoram a qualidade de vida e as habilidades comunicativas. Qualidade de Vida Relacionada à Saúde (QVRS), por ser um tema subjetivo de difícil mensuração, requer a utilização de questionários para tal aferição. Objetivo: Analisar e comparar a percepção de qualidade de vida de crianças e adolescentes usuárias de próteses auditivas na sua visão e de seus familiares/responsáveis, correlacionando-as com as características audiológicas e escolares. Método: Estudo transversal, quantitativo e descritivo, com entrevista estruturada e questionário. Amostra constituída por 25 sujeitos (crianças e adolescentes), idade entre 08 a 18 anos incompletos, diagnosticados com deficiência auditiva bilateral neurossensorial. Os procedimentos utilizados: anamnese; verificação das próteses auditivas; atualização dos dados audiológicos e o questionário Pediatric Quality of Life InventoryTM (PedsQL) versão 4.0 – Português – Brasil, para análise da percepção da QVRS de crianças /adolescentes e seus familiares/responsáveis. Conclusão: Sujeitos com diagnóstico de deficiência auditiva neurossensorial apresentaram semelhante percepção de QVRS comparada às respostas de seus familiares/responsáveis. As variáveis analisadas no perfil de uso da prótese auditiva não mostraram relação na QVRS dos sujeitos surdos. O grupo dos adolescentes evidenciou uma autopercepção de QVRS inferior à percebida pela faixa etária pediátrica.
Evolução da leitura e estrutura narrativa no reconto em escolares do segundo e terceiro anos do Ensino Fundamental I
Authors: Galvão Nicole Inêz , Souza Ariana De Assis , Pereira Edlaine Souza , Celeste Letícia Correa , Alves Luciana Mendonça
Published: January 2020

A compreensão configura um processo refinado, no qual as menores unidades de um texto são progressivamente integradas entre si e com o conhecimento do leitor. É possível verificar essa habilidade por meio do reconto. Este trabalho teve como objetivo realizar estudo da leitura e estruturas narrativas no reconto de escolares do 2º e 3º anos do Ensino Fundamental I. Foi realizada a gravação de leitura e reconto de texto narrativo, em voz alta, de 101 alunos do 2º e 3° anos de escolas pública e particular, seguida de aplicação de questionário de interpretação, contendo 10 questões de múltipla escolha, tendo apenas uma resposta correta para cada questão. Os dados coletados foram analisados segundo o Modelo de Compreensão de Texto de Estrutura Causal, foram realizadas análises descritivas, de associação e de correlação dos dados. A análise permitiu verificar que há associação com significância estatística entre: categorias do reconto e ano escolar; inferência com ano escolar e categorias do reconto; Interferência com categorias do reconto; reconstrução com sexo. As questões corretas não diferiram entre os anos, bem como o desempenho nas questões de inferências não diferiu para questões literais. Não houve classificação na melhor categoria de reconto. Foi possível verificar que há uma evolução entre segundo e terceiro anos em relação à narrativa do reconto, no que diz respeito a inferências, número de cláusulas no reconto, e acurácia. Os achados colaboram para técnicas mais assertivas nas habilidades avaliadas, reconhecimento de quando podem estar defasadas e identificação de métodos de aprendizagem mais adequados.
A alimentação com fórmula em recém-nascidos prematuros ou com baixo peso ao nascer
Authors: Feitosa Antonio Lucas Ferreira , Depolli Gabriel Trevizani , Flores Jorge Nicolás Silva , Assunção Monica Lopes de , Santana Maria Da Conceição Carneiro Pessoa de
Published: January 2020

Basuki F, Hadiati DR, Turner T, McDonald S, Hakimi M. Dilute versus full-strength formula in exclusively formula-fed preterm or low birth weight infants. Cochrane Database of Systematic Reviews 2019, Issue 6. DOI: 10.1002/14651858.CD007263.pub3.
Improving The Performance of Big Data Databases
Authors: Abdulqadir Ali Nzar , Arif Dashne Raouf
Published: January 2020

Real-time monitoring systems utilize two types of database, they are relational databases such as MySQL and non-relational databases such as MongoDB. A relational database management system (RDBMS) stores data in a structured format using rows and columns. It is relational because the values of the tables are connected. A non-relational database is a database that does not adopt the relational structure given by traditional. In recent years, this class of databases has also been referred to as Not only SQL (NoSQL).  This paper discusses many comparisons that have been conducted on the execution time performance of types of databases (SQL and NoSQL). In SQL (Structured Query Language) databases different algorithms are used for inserting and updating data, such as indexing, bulk insert and multiple updating. However, in NoSQL different algorithms are used for inserting and updating operations such as default-indexing, batch insert, multiple updating and pipeline aggregation. As a result, firstly compared with related papers, this paper shows that the performance of both SQL and NoSQL can be improved. Secondly, performance can be dramatically improved for inserting and updating operations in the NoSQL database compared to the SQL database. To demonstrate the performance of the different algorithms for entering and updating data in SQL and NoSQL, this paper focuses on a different number of data sets and different performance results. The SQL part of the paper is conducted on 50,000 records to 3,000,000 records, while the NoSQL part of the paper is conducted on 50,000 to 16,000,000 documents (2GB) for NoSQL. In SQL, three million records are inserted within 606.53 seconds, while in NoSQL this number of documents is inserted within 67.87 seconds. For updating data, in SQL 300,000 records are updated within 271.17 seconds, while for NoSQL this number of documents is updated within just 46.02 seconds.
Fungsi Malangge Bagi Masyarakat Nagari Koto Malintang
Authors: Sri Wahyuni Ningsih , Amri Emizal , Fitriani Erda
Published: January 2020

Penelitian ini mengkaji tentang fungsi Malangge bagi masyarakat di Nagari Koto Malintang. Pertanyaan penelitian, apa fungsi malangge bagi masyarakat. Pendekatan penelitian ini termasuk kualitatif dengan tipe penelitian studi etnografi Teknik pemilihan informan dengan purposive sampling. Data dikumpulkan melalui teknik: observasi, wawancara mendalam, dan studi dokumen. Untuk mendapat keabsahan data dilakukan triangulasi yaitu: triangulasi sumber. Data dianalisis menggunakan model analisis interaktif dari Miles dan Huberman. Temuan penelitian fungsi malangge  bagi masyarakat Nagari Koto Malintang adalah: Pertama, malangge sebagai fungsi ekonomi bagi masyarakat diantaranya: (1) menambah uang belanja. (2) mengisi pariuak bareh. (3) untuk membeli rokok sebatang. Kedua, malangge sebagai fungsi sosial bagi masyarakat, diantarnya: (1) untuk saling berbagi satu sama lain, (2) menjalin silaturrahmi. Ketiga, malangge ditengah-tengah masyarakat.
İlkokul Serbest Etkinlikler Uygulamasına İlişkin Bir Durum Çalışması
Authors: YILMAZ GÜNDÜZ Derya
Published: January 2020

Bu araştırma ilkokul 1-4. sınıflarda “Serbest Etkin-likler” uygulaması çerçevesinde okullarda neler yapıldığını ortaya koymak ve MEB tarafından bu uygulamaya geçilme gerekçeleri ile okullarda yapılan uygulamalar arasındaki uyumunu incelemek amacıyla, Ankara ilinde farklı ilçelerde yer alan iki okulda gerçekleştirilmiştir. Araştırma örnek durum araştırması olup veriler, gözlem ve görüşmeler yo-luyla “Öğretmen Görüşme Formu” “Odak Grup Görüşme Formu” ve “Ders Gözlem Formu” vasıtasıyla toplanmıştır. Verilerin analizinde ‘betimsel analiz yöntemi’ kullanılmıştır.
Elde edilen veriler sonucunda, en sık uygulanan et-kinlik kitap okuma iken en az yapılan etkinlikler şiir dinleme ve okuma, boyama etkinliği ile sınıf içi serbest faaliyetler olduğu görülmüştür. Serbest etkinlikler uygulaması çerçe-vesinde yapılan etkinliklerin farklı sınıf düzeylerinde değiş-mediği görülmüştür. Serbest etkinlikler uygulamasına ge-çilme gerekçeleri ile uygulamaların arasındaki benzerlik-lerden ziyade, farklılıkların fazla olduğu sonucuna ulaşıl-mıştır. Farklı sınıflarda görev yapan öğretmenlerin ve gö-rüşme yapılan öğrencilerin serbest etkinlikler uygulamasına ilişkin olumlu görüşte oldukları da belirlenmiştir.
Akademisyenlerin Gözünden Bilgisayar ve Öğretim Teknolojileri Eğitimi Bölümü’ne Bakış
Authors: BAKAR-ÇÖREZ Ayşegül , KOLBURAN GEÇER Aynur
Published: January 2020

Bilgisayar ve Öğretim Teknolojileri Eğitimi (BÖTE) Bölümü 1998 senesinde açılmıştır. Ancak, yapılan akademik çalışmalar ve bilimsel etkinliklerde düzenlenen paneller bölüm ile ilgili bir takım güncel sorunlara işaret etmektedir. Bu çalışma son zamanlarda BÖTE alanında ortaya çıkan sorunlarla birlikte akademisyenlerce sıklıkla tartışılan bir takım konuları bilimsel araştırma çerçevesinde araştırarak durum çalışması yapmayı amaçlamaktadır. Araştırma BÖTE’de görev yapmakta olan ve doktora derecesine sahip 43 akademisyenin açık uçlu sorulara vermiş oldukları yanıtları kapsamaktadır. Yapılan analizler akademisyenlerin alana bakış açısını ortaya koymakta ve akademisyenlerin gözünden bölümde yaşanan sorunları ve bu sorunların nasıl çözülebileceğini göstermektedir. Çalışma, aynı zamanda, alanda görev yapmakta olan akademisyenlerin farklı görüşlere sahip olduğunu da ortaya koymaktadır. Görüş farklılıkları akademisyenlerin farklı disiplinlerden geliyor olmalarıyla açıklanabilir.
Daily Life of Students of the Women’s Gymnasium of Yakutia in the Late 19th – Early 20th Centuries
Authors: Makarova Agrafena Innokentyevna ,   North-Eastern Federal University,   Siberian branch of the Russian Academy of Sciences
Published: January 2020

The paper analyses the daily life of students of the Yakut women’s gymnasium. The author, based on archival and published materials, studies the organization of classes, living conditions and leisure of students. In general, the curriculum and the events held within the walls of the Yakut women’s gymnasium did not differ from the national ones. However, it was found that the curriculum of women’s gymnasium provided a limited amount of knowledge compared to the men’s one. The specificity of everyday life of schoolgirls was determined by a complex of factors: the climate of the area, the well-being of their parents, the sanitary and hygienic conditions of the classroom. A characteristic feature of life of educational institutions at the beginning of the 20th century in Russia was students’ participation in the revolutionary movement. Students and graduates of the Yakut women’s gymnasium, who became members of revolutionary circles and active participants in revolutionary events and the Civil War in Yakutia afterwards, were no exception.
France Getting Mandate to Syria: the Way From Mudros to Sèvres
Authors:   Taurida Academy (Academic Unit) of V.I. Vernadsky Crimean Federal University, Bershov Vladimir Nikolaevich
Published: January 2020

The paper distinguishes between the spheres of influence of the Entente countries in the Ottoman Empire after World War I and the actions of French diplomacy, which led to getting the French mandate for Syrian vilayets. The emphasis is put on the Armistice of Mudros, which served as the starting point for the collapse of the Ottoman Porte. It is noted that the actual breakdown of the empire was carried out by the Entente countries on results of the agreement in San Remo and at the points of the Treaty of Sèvres. These events led to agreements between France and England, in the aftermath of which France won the mandate for Syrian vilayets of the Ottoman Empire. As part of the conducted research, the articles of the French mandate were translated into Russian. The present work is intended for specialists in the field of world history (of modern and contemporary times), Orientalist scholars and for all who are not indifferent to Middle Eastern studies.
«Vicente de la Fuente y el costumbrismo estudiantil», de Fermín Ezpeleta Aguilar
Authors: Martínez Crespo Sara
Published: January 2020

Reseña del libro Vicente de la Fuente y el costumbrismo estudiantil (Zaragoza, Taula Ediciones, 2019), de de Fermín Ezpeleta Aguilar.

En él se recogen ocho "costumbres estudiantinas" del escritor aragonés, precedidas por un estudio introductorio en el que se repasa la vida de autor y se contextualiza la lectura de estos textos dentro del costumbrismo.
«Para una teoría de las distancias», de Lorenzo Oliván
Authors: Abril Juan Carlos
Published: January 2020

Reseña del libro Para una teoría de las distancias (Barcelona, Tusquets, col. Nuevos Textos Sagrados, 2018), de Lorenzo Oliván.
ANALISIS KINERJA KEUANGAN USAHA KECIL DAN MENENGAH DI KOTA TASIKMALAYA
Authors: Kostini Nenden , Dai Ratna Meisa
Published: January 2020

Classic problems that are often encountered in Small and Medium Enterprises are generally related to the lack of management capabilities in working capital management. These limitations cause difficulties in measuring the financial performance of Small and Medium Enterprises. Measurement of financial performance, generally uses complex financial indicators for large companies so that it is not suitable when applied to Small and Medium Enterprises. This study aims to determine the condition of the financial performance of Small and Medium Enterprises in the City of Tasikmalaya. Measurement of financial performance uses simple financial ratios, which consist of current ratio, debt ratio and net margin ratio. The population and sample in this study are Small and Medium Enterprises in the Creative Industry Sector in the City of Tasikmalaya with 48 Small and Medium Enterprises. In addition to in-depth interviews with Small and Medium Enterprises, documentation studies were also conducted to collect secondary data. Processing data using a comparative or comparison method. The results of data processing show that the financial position of most of the Small and Medium Enterprises in Tasikmalaya City is in a liquid condition because the position of current assets is still greater than the current debt, and the profitability is quite good. Permasalahan klasik yang sering ditemui pada Usaha Kecil Menengah, umumnya berkaitan dengan minimnya kemampuan manajemen dalam pengelolaan modal kerja. Keterbatasan tersebut menyebabkan kesulitan dalam pengukuran kinerja keuangan Usaha Kecil Menengah. Pengukuran kinerja keuangan, umumnya menggunakan indikator keuangan yang kompleks untuk perusahaan besar sehingga tidak sesuai bila diterapkan pada Usaha Kecil Menengah. Penelitian ini bertujuan untuk mengetahui kondisi kinerja keuangan Usaha Kecil Menengah di Kota Tasikmalaya. Pengukuran kinerja keuangan menggunakan rasio keuangan sederhana, yang terdiri dari current rasio, debt rasio dan net margin rasio. Metode penelitian dalam penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian deskriptif. Adapun yang menjadi populasi dan sampel dalam penelitian ini adalah Usaha Kecil Menengah pada Sektor Industri Kreatif di Kota Tasikmalaya sebanyak 48 Usaha Kecil dan Menengah. Selain wawancara mendalam dengan pelaku Usaha Kecil Menengah, dan Dinas KUKM Kota Tasikmalaya, studi dokumentasi juga dilakukan untuk mengumpulkan data sekunder. Pengolahan data menggunakan metode komparatif atau perbandingan. Hasil penelitian menunjukkan bahwa posisi keuangan sebagian besar Usaha Kecil Menengah di Kota Tasikmalaya berada dalam kondisi yang likuid karena posisi harta lancar masih lebih besar daripada utang lancarnya, serta profitabilitas yang cukup baik. Hal ini terlihat dari kondisi current rasio yang menunjukkan