bluuebunny/crossref_metadata_2025 huggingface dataset:
Hexokinase and glucokinases are essential for fitness and virulence in the pathogenic yeastCandida albicans
Authors: Laurian Romain , Dementhon Karine , Doumèche Bastien , Soulard Alexandre , Noel Thierry , Lemaire Marc , Cotton Pascale
Published: October 2018

Metabolic flexibility promotes infection and commensal colonization by the opportunistic pathogenCandida albicans.Yeast cell survival depends upon assimilation of fermentable and non-fermentable locally available carbon sources. Physiologically relevant sugars like glucose and fructose are present at low level in host niches. However, because glucose is the preferred substrate for energy and biosynthesis of structural components, its efficient metabolization is fundamental for the metabolic adaptation of the pathogen. We explored and characterized theC. albicanshexose kinase system composed of one hexokinase (CaHxk2) and two glucokinases (CaGlk1 and CaGlk4). Using a set of mutant strains, we found that hexose phosphorylation is mostly assured by CaHxk2, which sustains growth on hexoses. Our data on hexokinase and glucokinase expression point out an absence of cross regulation mechanisms at the transcription level and different regulatory pathways. In the presence of glucose, CaHxk2 migrates in the nucleus and contributes to the glucose repression signaling pathway. In addition, CaHxk2 participates to oxidative, osmotic and cell wall stress responses, while glucokinases are overexpressed under hypoxia. Hexose phosphorylation is a key step necessary for filamentation, that is affected in the hexokinase mutant. Virulence of this mutant is clearly impacted in theGalleria mellonellaand macrophage models. Filamentation, glucose phosphorylation and stress response defects of the hexokinase mutant prevent host killing byC. albicans.By contributing to metabolic flexibility, stress answer response and morphogenesis, hexose kinase enzymes play an essential role in the virulence ofC. albicans.

Author summary

The pathogenic yeastC. albicansis both a powerful commensal and pathogen of humans that can infect wide range of organs and body sites. To grow in its host and establish an infection, the pathogen must assimilate carbon from these heterogenous environments.C. albicansregulates central carbon metabolism in a niche-specific manner, activating alternatively gluconeogenesis, glyoxylate cycle and the glycolytic metabolism. For yeast and other microorganisms, glucose is the preferred carbon and energy source and its accurate detection and metabolism is essential. However, the glycolytic hexose kinase system has not been investigated yet inC. albicans.In this report, we showed that hexokinase and glucokinases contribute to the fitness and virulence ofC. albicans.We revealed the main metabolic role of the hexokinase CaHxk2 which impacts on growth, glucose signalling, morphological transition and virulence. However, glucokinases contribute to the anoxic response and their implication in regulation processes is suggested.
Gating modules of the AMPA receptor pore domain revealed by unnatural amino acid mutagenesis
Authors: Poulsen Mette H. , Poshtiban Anahita , Klippenstein Viktoria , Ghisi Valentina , Andrew Plested
Published: October 2018

Ionotropic glutamate receptors (iGluRs) are responsible for fast synaptic transmission throughout the nervous system. Conformational changes of the transmembrane domain (TMD) underlying ion channel activation and desensitization remain poorly understood. Here, we explored the dynamics of the TMD of AMPA-type iGluRs using genetically-encoded unnatural amino acid (UAA) photo-crosslinkers, p-benzoyl-L-phenylalanine (BzF) and p-azido-L-phenylalanine (AzF). We introduced UAAs at sites throughout the TMD of the GluA2 receptor and characterized these mutants in patch-clamp recordings, exposing them to glutamate and UV light. This approach revealed a range of optical effects on the activity of mutant receptors. We found evidence that an interaction between the Pre-M1 and the M4 TMD helix was essential for normal activation and desensitization. Photoactivation at F579AzF, a residue behind the selectivity filter, had extraordinarily broad effects on gating and desensitization. This observation suggests coupling to other parts of the receptor and like in other tetrameric channels, selectivity filter gating.
Aberrant PRDM9 expression impacts the pan-cancer genomic landscape
Authors: Houle Armande Ang , Gibling Heather , Lamaze Fabien C. , Edgington Hilary A. , Soave David , Fave Marie-Julie , Agbessi Mawusse , Bruat Vanessa , Stein Lincoln D. , Awadalla Philip
Published: October 2018

The binding of PRDM9 to chromatin is a key step in the induction of DNA double-strand breaks associated with meiotic recombination hotspots; it is normally expressed solely in germ cells. We interrogated 1879 cancer samples in 39 different cancer types and found that PRDM9 is unexpectedly expressed in 20% of these tumors even after stringent gene homology correction. The expression levels of PRDM9 in tumors are significantly higher than those found in healthy neighboring tissues and in healthy nongerm tissue databases. Recurrently mutated regions located within 5 Mb of the PRDM9 loci, as well as differentially expressed genes in meiotic pathways, correlate with PRDM9 expression. In samples with aberrant PRDM9 expression, structural variant breakpoints frequently neighbor the DNA motif recognized by PRDM9, and there is an enrichment of structural variants at sites of known meiotic PRDM9 activity. This study is the first to provide evidence of an association between aberrant expression of the meiosis-specific gene PRDM9 with genomic instability in cancer.
A coaxial alignment method for large aircraft component assembly using distributed monocular vision
Authors: Li Shuanggao , Deng Zhengping , Zeng Qi , Huang Xiang
Published: October 2018

Purpose

The assembly of large component in out-field is an important part for the usage and maintenance of aircrafts, which is mostly manually accomplished at present, as the commonly used large-volume measurement systems are usually inapplicable. This paper aims to propose a novel coaxial alignment method for large aircraft component assembly using distributed monocular vision.

Design/methodology/approach

For each of the mating holes on the components, a monocular vision module is applied to measure the poses of holes, which together shape a distributed monocular vision system. A new unconstrained hole pose optimization model is developed considering the complicated wearing on hole edges, and it is solved by a iterative reweighted particle swarm optimization (IR-PSO) method. Based on the obtained poses of holes, a Plücker line coordinates-based method is proposed for the relative posture evaluation between the components, and the analytical solution of posture parameters is derived. The required movements for coaxial alignment are finally calculated using the kinematics model of parallel mechanism.

Findings

The IR-PSO method derived more accurate hole pose arguments than the state-of-the-art method under complicated wearing situation of holes, and is much more efficient due to the elimination of constraints. The accuracy of the Plücker line coordinates-based relative posture evaluation (PRPE) method is competitive with the singular value decomposition (SVD) method, but it does not rely on the corresponding of point set; thus, it is more appropriate for coaxial alignment.

Practical implications

An automatic coaxial alignment system (ACAS) has been developed for the assembly of a large pilotless aircraft, and a coaxial error of 0.04 mm is realized.

Originality/value

The IR-PSO method can be applied for pose optimization of other cylindrical object, and the analytical solution of Plücker line coordinates-based axes registration is derived for the first time.
Chinese perception and willingness to buy Taiwanese brands
Authors: Souiden Nizar , Ladhari Riadh , Chang Liu
Published: October 2018

Purpose

The purpose of this paper is to examine ethnocentrism and animosity in a special context of two societies that share cultural, historical, ethnic and geographical characteristics. In particular, it first investigates the relationships between Chinese ethnocentrism and animosity toward Taiwan, and then it examines the impact of these two factors on the Chinese perception of Taiwanese brand quality and their purchase intent.

Design/methodology/approach

Based on a sample of 605 respondents from China, data were analyzed by structural equation modeling.

Findings

The results show that although Chinese animosity toward Taiwan is moderate, it is significantly driven by ethnocentrism, which has a significant and negative effect on willingness to buy, but not on the perception of Taiwanese brand quality. The Chinese animosity toward Taiwan, however, has negative and significant effects on their perception of Taiwanese brand quality and their intention of purchasing Taiwanese brands.

Research limitations/implications

The immense size of the country has impeded the representativeness of the authors’ sample and the generalizability of the results. Also, the study covers only one type of product.

Practical implications

Forming partnerships with local Chinese businesses and developing strong ties with local communities could be considered as a solution to minimize or circumvent the effect of animosity and might help foreign companies appear more “local.”

Originality/value

In contrast to past studies that investigated ethnocentrism and animosity in the context of countries presenting several differences (e.g. China vs USA), this study investigates the effect of ethnocentrism and animosity in the context of two countries (China and Taiwan) that share cultural, historical, ethnic and geographic characteristics. Despite the strong ties between the two countries, the Chinese have a certain animosity, though moderate, toward Taiwan and consequently are less inclined to buy Taiwanese brands. This implies that Chinese animosity toward a country may be toned down or pronounced, depending on whether they have strong or weak ties with that country.
Organic shoppers’ involvement in organic foods: self and identity
Authors: Kim Yun-Hee
Published: October 2018

Purpose

The purpose of this paper is to understand how identities drive customer values, attitudes toward organic foods and satisfaction, all of which influence world or mouth (WOM).

Design/methodology/approach

Questionnaire surveys were administered to the purchasers of organic foods. In total, 512 completed responses were obtained for data analysis.

Findings

Strongly defined social identity and role identity are significant antecedents of consumers’ health consciousness and socially responsible consumer behavior (SRCB). This finding explains why organic shoppers value their health and the environment (i.e. self- and others-oriented values). Additionally, health consciousness and SRCB significantly influence attitudes toward organic foods. The study reveals that attitudes toward organic foods positively influence organic shoppers’ satisfaction, and their satisfaction increases positive WOM. Finally, the moderating effects of involvement and mass media are examined. When organic shoppers are strongly involved with organic foods, their health consciousness has a more positive effect on their attitudes toward organic foods. However, organic shoppers’ involvement did not moderate the effect of SRCB on attitudes toward organic foods. Likewise, the mass media did not moderate the effect of health consciousness and SRCB on attitudes toward organic foods.

Originality/value

This study incorporates critical factors such as the antecedents of the customer values to develop a comprehensive model for understanding of organic shoppers’ consumption of organic foods.
An analysis of the farmers contractual preferences in process innovation implementation
Authors: Martino Gaetano , Polinori Paolo
Published: October 2018

Purpose

The purpose of this paper is to consider how farmers cope with the uncertainty-related broiler process innovation in long-term contractual relationships.

Design/methodology/approach

This paper conceptualizes the process innovation implementation in terms of governance structure adaptation. The focus of the study is on the property and decision rights combination in process innovation implementation. It is argued that this approach highlights a key aspect of the nexus between governance mode and innovation within inter-firms relationships.

Findings

The results first show that the allocation of the decision rights between the farmer and the processor explains the process innovation implementation and, second, that the farmer contractual preferences are caused by the expected costs of the adaptation. Third, estimates of transaction and production costs variations are proposed.

Research limitations/implications

This study considers only the uncertainty stemming from the process innovation, whereas further uncertainty sources may influence the contract negotiation. Second, the lack of sample representativeness requires further information to be gathered. Finally, the investigation could be developed by modeling the farmer-processor negotiation.

Practical implications

The results indicate that effective governance structures in poultry production should give room to the adaptation in order to facilitate process innovation.

Originality/value

To conceptualize the process innovation implementation as an adaptation of the governance structure strengthens the knowledge of innovation in the sector context and contributes to the extent of the applied field of transaction cost economics.
Farmer behavior and perception regarding food waste and unsold food
Authors: Bonadonna Alessandro , Matozzo Andrea , Giachino Chiara , Peira Giovanni
Published: October 2018

Purpose

The purpose of this paper is to analyze farmer behavior, considering their attitude toward food waste with particular focus on their involvement in the last phase of the process, the retail phase. It assesses the different approaches applied to food waste management and its future.

Design/methodology/approach

A sample of 35 farmers in thePorta Palazzomarket, the biggest food market in the Turin Area (north-west Italy), was identified and a survey was carried out to determine the behavior and perception of farmers regarding food waste and the management of unsold food.

Findings

Results show that there is a high level of interest on the ethical and charitable aspects of food waste and unsold food. However, awareness and knowledge of the initiatives organized by institutions are not sufficient.

Practical implications

If policy makers and institutions have an understanding of farmer behavior, they can implementad hocinitiatives to reduce food waste and build on the work already done by farmers. Additionally, farmers can help customers to better understand the products.

Originality/value

This study analyzes the perception of the food waste phenomenon for one type of traditional operator in the food supply chain, the farmer. The originality of the paper lies in the fact that it has not only considered the perception of food waste but also the management of unsold food in a market area.
Age and size dependencies of firm failure processes: an analysis of bankrupted Estonian firms
Authors: Lukason Oliver
Published: October 2018

Purpose

This study aims to find out whether firm failure processes are age- and size-dependent.

Design/methodology/approach

The sample consists of 333 bankrupted Estonian firms. Failure processes are detected with consecutive factor and cluster analyses of six financial variables calculated for three pre-failure years. Multinomial logistic regression is applied to study the interconnections between failure processes (dependent variable) and firm size and age (independent variables). In addition, the contingency between detected failure processes and failure causes obtained from court judgements are studied.

Findings

Three failure processes are detected, of which the predominant one accounting for 55 per cent of cases is a gradual failure process, indicating a step-by-step decline in the values of financial variables. The two minority processes are mixed, meaning that some financial variables are poor for many years before the bankruptcy and others decrease only shortly before bankruptcy declaration. With an increase in firm size, the gradual failure process becomes more common, but in turn, the presence of the gradual failure process is not age-dependent. Failure causes detected by trustees are not associated with failure processes.

Originality/value

This paper is the first one to specifically outline the age and size dependencies of firm failure processes. In addition, the interconnection of failure causes and firm failure processes detected with financial variables are rarely studied topics.
What makes up intentions to purchase the pioneer? A theory of reasoned action approach in India and the USA
Authors: Mady Tarek
Published: October 2018

Purpose

The purpose of this paper is to extend the research paradigm focusing on behaviorally-based first-mover advantages (FMA) by applying the widely-accepted Theory of Reasoned Action (TRA) and offers insights into differences between a mature market (USA) and an emerging market (EM) (India) regarding how intentions to purchase the pioneer are formed.

Design/methodology/approach

Utilizing samples of 208 USA and 194 Indian consumers, hypotheses examining the underlying beliefs, attitudes, social norms and purchasing intentions regarding pioneer brands are developed and tested using structural equation modeling.

Findings

Insights from the study suggest the TRA provides a means for assessing behaviorally-based FMAs across cultures, even as manifestations of purchase intentions differ significantly. According to the TRA and findings of this study, intentions are a function of overall attitudes and social norms. In the USA, individual attitudes were found to play a more significant role than social norms in formulating purchase intention. In India, social norms played a more dominant role in intention formation.

Originality/value

The study represents one of the first empirical attempts to shed light on the extent of behaviorally-based FMAs in an EM and how manifestations of intention to purchase the pioneer differ from mature markets. The study expands the behavioral paradigm of analysis to include one of the most sought-after EMs today (India) and provides one of the first empirical studies to utilize the TRA in addressing behaviorally-based FMAs.
Determinants of foreign direct and indirect investments from the institutional perspective
Authors: Wang Liu , Li Shaomin
Published: October 2018

Purpose

Amid the rising concerns about the unbalanced globalization, there has been a renewed interest in examining the pattern of international trade and investment, especially between emerging and mature economies. In this study, the purpose of this paper is to examine the role of different institutional and market-related determinants in shaping the pattern and mode of foreign investments in emerging and developed markets.

Design/methodology/approach

The empirical investigation is based on a balanced panel sample of 45 countries (28 developed countries and 17 emerging economies) over an 11-year period from 2002 to 2012. A series of multivariable regressions are conducted to evaluate both the trend and the mode of foreign investment with rigorous robustness checks.

Findings

Overall, the authors find that market openness and capital market development are the main determinants of a country’s ability to attract foreign investment in developed countries, while the governance environment is the key consideration in emerging markets. Regarding the mode of foreign investment, the authors find that, in developed markets, foreign investors tend to choose direct investment in the countries with more open markets. In emerging markets, however, the choice between direct and indirect (portfolio) investments is mainly driven by arbitrage activities, where investors opt for portfolio investment when the stock market is undervalued.

Practical implications

First, the findings may aid foreign investors in their strategic choice between emerging vs mature markets based on the governance environment, market openness, capital market development and arbitrage opportunities. Second, the findings may be used to aid governments in prioritizing institutional improvement in market openness, stock market development and policies aimed at balancing different investment channels.

Social implications

The study may enhance the social understanding on the current debate on the winners and losers of globalization. A main complaint from mature economies is that the emerging economies took their jobs away and, therefore, they should adopt protectionism (which implies closing their own markets) in order to preserve jobs. The study shows that such a reaction may not be in the best interests of the mature economies since they will be able to attract more foreign investment (which implies creating or at least keeping more jobs) if they make their markets more open.

Originality/value

Existing studies on foreign investment have primarily focused on direct investment. The study examines both the direct and indirect investments and the way in which they affect the foreign investment markets in emerging and mature economies. From the institutional perspective, the authors show how the governance environment and market factors affect foreign investors’ strategic choice between direct and indirect investment, contingent upon the stage of a country’s economic and institutional development.
Health needs and risky behaviours among inmates in the largest prison of eastern Nepal
Authors: Shrestha Gambhir , Mulmi Rashmi , Yadav Deepak Kumar , Baral Dharanidhar , Yadav Birendra Kumar , Chakravartty Avaniendra , Pokharel Paras Kumar , Sapkota Nidesh
Published: October 2018

Purpose

The purpose of this paper is to assess the health status and risky behaviours of inmates in Nepal.

Design/methodology/approach

This cross-sectional study was conducted in Jhumka Regional Prison, the largest male prison in eastern Nepal from September 2014 to August 2015. Data were collected through face-to-face interviews from 434 randomly selected incarcerated participants using semi-structured questionnaires.

Findings

The mean age of 434 participants was 35.7 years (SD 13.3). The majority (84 per cent) had at least one current health problem, of which the commonest were respiratory (50 per cent), skin (38 per cent) and digestive (26 per cent). Alcohol (73 per cent) and cigarettes (71 per cent) were the most commonly used substances prior to imprisonment. Approximately, 27 and 11 per cent reported illicit drug use and injectable drug use prior to incarceration, respectively. A total of 204 inmates reported having intercourse with sex workers. Of these, 49 per cent did not use a condom in their last intercourse with a sex worker.

Research limitations/implications

This paper illustrates that a wide range of physical and mental health problems exist among incarcerated people in Nepal. The study may lack generalisability, however, as it was conducted in a single male prison.

Practical implications

The paper suggests a need for medical, psychiatric and substance abuse care in correctional settings to improve the health status of the prison population. It is also important to develop screening policies for blood-borne viral and other infectious diseases in the prison.

Originality/value

This is the first study of its kind drawn from prisons in Nepal.
Can artificial neural networks predict lawyers’ performance rankings?
Authors: Lopes Susana Almeida , Duarte Maria Eduarda , Almeida Lopes João
Published: October 2018

Purpose

The purpose of this paper is to propose a predictive model that could replace lawyers’ annual performance rankings and inform talent management (TM) in law firms.

Design/methodology/approach

Eight years of performance rankings of a sample of 140 lawyers from one law firm are used. Artificial neural networks (ANNs) are used to model and simulate performance rankings over time. Multivariate regression analysis is used to compare with the non-linear networks.

Findings

With a lag of one year, performance ranking changes are predicted by the networks with an accuracy of 71 percent, over performing regression analysis by 15 percent. With a lag of two years, accuracy is reduced by 4 percent.

Research limitations/implications

This study contributes to the literature of TM in law firms and to predictive research. Generalizability would require replication with broader samples.

Practical implications

Neural networks enable extended intervals for performance rankings. Reducing the time and effort spent benefits partners and lawyers alike, who can instead devote time to in-depth feedback. Strategic planning, early identification of the most talented and avenues for tailored careers become open.

Originality/value

This study pioneers the use of ANNs in law firm TM. The method surpasses traditional static study of performance through its use of non-linear simulation and prediction modeling.
Four facets of learning in performance measurement
Authors: Martin Jason , Elg Mattias , Wallo Andreas , Kock Henrik
Published: October 2018

Purpose

The purpose of this paper is to contribute to a better understanding of the role of learning in performance measurement.

Design/methodology/approach

The authors develop a theoretical framework combining workplace learning theory with purposes of performance measurement. The authors elaborate this framework empirically by identifying critical incidents from a case set within a context containing a broad range of different performance measurement activities. Finally, the authors discuss the results and the possible implications for using the theoretical framework in order to better understand facets of learning regarding the design of performance measurement.

Findings

Workplace learning theory provides a deeper understanding of how the mechanisms of performance measurements support control or improvement purposes. The authors propose a tentative framework for learning as a driver for performance measurement and four facets of learning are identified: reproductive, rule-oriented, goal-oriented and creative learning.

Research limitations/implications

The empirical material is limited to the healthcare context and further studies are needed in order to validate the findings in other settings.

Practical implications

The authors argue that all managers must consider what kind of learning environment and what kind of learning outcomes best serve the interests of their organisation. Purposeful and carefully designed organisational arrangements and learning environments are more likely to induce intended learning outcomes.

Originality/value

Previous connections between the fields of “performance measurement” and “workplace learning” often lack any deeper conceptualisations or problematisations of the concept of learning. In this paper, the authors provide a more nuanced discussion about the process of learning in performance measurement, which may provide a basis for further research and scholarly attention.
Productivity paradox? The impact of office redesign on employee productivity
Authors: Yunus Erlinda N. , Ernawati Erni
Published: October 2018

Purpose

The purpose of this paper is twofold: first, to investigate the relationship between office redesign and employee productivity; and second to highlight the impact of privacy on work productivity across different generations.

Design/methodology/approach

This study examines open-office policy more comprehensively by integrating socio-behavioral and physical aspects of the office, and by using a mixed-method approach that incorporates most significant change, factor analysis and hierarchical regression analysis. Using a census method, the respondents were all consultants and trainers in an educational institution who were experiencing office design changes from a combi, cellular-like office to a more open, non-territorial office.

Findings

Three variables emerged as impacts of office redesign perceived by respondents: friendship, collaboration and privacy. Collaboration and privacy exert a positive influence on work productivity, while friendship does not. The relationship between privacy and work productivity is stronger for the Generation Y than for senior employees, namely, the Baby Boomers and Generation X.

Research limitations/implications

This study examines the impacts of office redesign in one organization. Future studies should advance the findings by empirically testing the theoretical model in broader contexts. Future studies could also enrich the literature by bringing cultural aspects into the discussion and comparing Asian-based and European or Western-based findings.

Practical implications

For Gen Y employees who prefer freedom, mobility and flexibility to personalization in their workplace, the open office could be a better solution for organizations that aim for both work productivity and efficiency.

Originality/value

This study provides an empirical value by using a mixed method of qualitative and quantitative research. This study further contrasts the different perspectives of an office redesign between younger and older generations.
Integrated management systems diffusion models in South European countries
Authors: Cabecinhas Mónica , Domingues Pedro , Sampaio Paulo , Bernardo Merce , Franceschini Fiorenzo , Galetto Maurizio , Gianni Maria , Gotzamani Katerina , Mastrogiacomo Luca , Hernandez-Vivanco Alfonso
Published: October 2018

Purpose

The purpose of this paper is to dissect the diffusion of the number of organizations that implemented multiple management systems (MSs), considering the International Organization for Standardization (ISO) 9001, ISO 14001 and OHSAS 18001 standards (quality, environment and safety) in the South European countries: Italy, Portugal and Spain. In addition, based on the data collected, forecasting models were developed to assess at which extent the multiple certifications are expected to occur in each studied country.

Design/methodology/approach

Data concerning the evolution of the amount of multiple MSs in Italy, Portugal and Spain were collected for the period between 1999 and 2015. The behavior of the evolution of the number of MSs over the years was studied adopting both the Gompertz and the Logistic models. The results obtained with these two models were compared and analyzed to provide a forecast for the next years.

Findings

The diffusion throughout the years of the number of MSs presents an S-shaped behavior. The evolution of the amount of MSs in countries with a lower saturation level are properly fitted by the Gompertz model whereas the Logistic model fits more accurately when considering countries with a larger saturation level.

Research limitations/implications

The data related to the early years are not available in some of the countries. To overcome this shortcoming missing data were extrapolated from the data set provided by the annual ISO survey. Additionally, the integration level attained by each company was not assessed and, on this regard and in the scope of this paper, an integrated management system is understood as implemented when organizations have multiple MSs implemented.

Practical implications

The results provide a cross-sectional portrayal of the diffusion of MSs certifications in the South European countries and enable a forecast for the trend in the next years.

Originality/value

This study aims for the first time, to the best of the authors’ knowledge, to analyze the diffusion of multiple MSs throughout the years.
Consumer safety complaints and organizational learning: evidence from the automotive industry
Authors: Sarkar Sourish , Rajagopalan Balaji
Published: October 2018

Purpose

The purpose of this paper is to investigate the value of information in consumer safety complaints for organizational learning.

Design/methodology/approach

Empirical analysis of this study uses a novel secondary data set, which is formed by combining complaints data filed with the National Highway Traffic Safety Administration (NHTSA) for potential safety defects, and design change information from 2003 to 2011 model-year vehicles in the USA.

Findings

First, the paper demonstrates the value of information embedded in complaints. Second, in the case of radical product redesigns, owing to the lack of direct applicability of consumer feedback based learning, the impact of learning on product safety is found to be muted, third, the results suggest that the safety complaint rates vary by vehicle classes/categories and, fourth, the findings differ from prior research conclusions on vehicle quality. Prior research finds the debuting car models have the lowest repair rates among all car models produced in a given year, but the current study finds the debuting models to have the highest rates of safety complaints.

Originality/value

Quality management literature rarely examines the safety complaints data (which, unlike other consumer feedbacks, focuses exclusively on the safety hazards due to flaws that result in accidents). This paper fills the gap in literature by linking safety complaints with future product quality and organizational learning.
Developing a structured framework for measuring police efficiency
Authors: Asif Muhammad , Shahzad Muhammad , Awan Muhammad Usman , Akdogan Huseyin
Published: October 2018

Purpose

The growing emphasis on “managerialism” in police and the pressure to employ scientific methods of performance measurement warrants the need for a structured framework. The scope of police duties is large as it relates to several preventive and corrective action related to public safety and crime management. A challenge in measuring police performance is to take into consideration a range of variables that can potentially influence performance. The purpose of this paper is to provide a structured framework for measuring different facets of police efficiency, which is especially useful in managerial decision making.

Design/methodology/approach

This paper uses data envelopment analysis and discusses efficiency measurement in terms of the technical, managerial and scale efficiency, resources utilization patterns, returns-to-scale analysis and measurement of super-efficiency. The application of framework is based on the data of the police stations of Lahore, a large metropolitan city in Pakistan.

Findings

The paper shows the application of different measures of efficiency in making decisions pertaining resources allocation, prioritizing areas for improvement and identifying benchmarks for performance improvement. Different measures of efficiency are presented in the form of a structured framework.

Practical implications

Managers can use this framework to glean rich insights into different types of efficiency and sources of inefficiency. Further, a discussion of variables provided in this paper can be especially useful in determining trade-offs during the selection of inputs and outputs.

Originality/value

The key contribution of this paper is in providing a multifaceted efficiency measurement framework, that is capable of providing rich insights into the sources of inefficiency and helps scientific decision making. To the best of our knowledge, such a multifaceted approach has not been provided in previous publications.
An empirical investigation of implementing Lean Six Sigma in Higher Education Institutions
Authors: Sunder M. Vijaya , Mahalingam Sanjay
Published: October 2018

Purpose

The purpose of this paper is to empirically investigate the applicability and implementation of Lean Six Sigma (LSS) in Higher Education Institutions (HEIs). LSS is considered as the most recent service quality practice which has proved its success in manufacturing and service sectors. Though there is plenty of literature available with regard to the application and benefits of LSS in services sectors (like Banking, healthcare, information technology sectors, etc.), there is apparently no evidence in the literature about the implementation of LSS in HEIs.

Design/methodology/approach

A five-phased approach is followed. A multiple case-study method is used in this paper to explore this implementation of LSS in two select international University colleges. LSS toolkit comprising of define-measure-analyze-improve-control phases is used for the execution of the projects. Featuring student teams in LSS project management adds novelty to the approach.

Findings

The paper empirically validates the application of LSS in HEIs. Further, it highlights the practical challenges and benefits of LSS in the HEI setup. An in-depth empirical analysis of LSS toolkit application, LSS change management and using student teams in LSS project management are the highlights of this paper. The paper concludes that LSS is applicable and could provide positive benefits to HEIs.

Research limitations/implications

LSS application in HEIs is perhaps a new research area, which is at its nascence and upcoming in the researchers’ community. Hence, this paper would serve as a platform and provide directions for future scholars to ponder on the subject.

Practical implications

Since the cases are executed in the real-time setup of HEIs, the paper has several practical implications. First, the academia and practitioners’ collaboration in executing projects adds novelty. Second, the involvement of student teams from project selection to execution brings in practical perspectives alongside the academic education. Several other key lessons learned and benefits of LSS in HEI setup are presented as part of the paper.

Originality/value

LSS has been successful in the past few decades in the manufacturing and service sectors. However, its application in HEIs was very nascent, and few researchers even doubted its relevancy of application in HEIs. This study illustrates its importance and application to the higher education sector which is a highly responsible area of the service sector, for imbibing quality excellence, serving as an excellent resource for researchers and higher education professionals.
Factor analysis-validated comprehensive employee job performance scale
Authors: Na-Nan Khahan , Chaiprasit Kanokporn , Pukkeeree Peerapong
Published: October 2018

Purpose

The purpose of this paper is to develop an employee job performance (EJP) scale questionnaire that encompasses the job time, job quality and job quantity dimensions of employee performance.

Design/methodology/approach

In this study, the questionnaire questions were first validated using exploratory factor analysis (EFA) and then confirmatory factor analysis (CFA) along the three performance dimensions. The research samples were auto-parts assembly line workers. The factor analysis results confirmed the validity of the questionnaire as a reliable employee performance evaluation tool, as evidenced by the composite reliability (CR) and the average variance extracted (AVE).

Findings

The questionnaire questions identified three factors of EJP, namely, job time, job quality and job quantity, with 13 items. The factor analysis results confirmed the validity of the questionnaire as a reliable employee performance evaluation tool, as evidenced by a CR of 0.894 and AVE of 0.739, in addition toχ2=63.340, df=54,p=0.180, goodness of fit index=0.976, adjusted goodness of fit index=0.960, RMSEA=0.021 and root mean square residue=0.014.

Research limitations/implications

The EJP scale questionnaire was examined using only EFA and CFA. These scales are expected to help academics, researchers and practitioners test theories. Because of the features of the sample, the final results should be considered carefully.

Practical implications

Importantly, the factor analysis results suggest that the proposed EJP scale questionnaire can be applied to various industries and settings either as is or with minimal modifications.

Originality/value

The EJP questionnaire is novel and can serve as an excellent EJP tool to measure employees’ behavioral output. The questionnaire can provide empirical data on employee performance output based on the employee’s perspective.
A six sigma based approach to evaluate the on time performance of Indian railways
Authors: Vaidya Omkarprasad S.
Published: October 2018

Purpose

The purpose of this paper is to propose an approach to evaluate “on time” performance for a class of Indian railways (IR). This approach is build-up on the theme of six sigma level computation for continues data. The arrival data obtained from a class of IR called “Rajdhani Express” exhibited a unique characteristic: neither did the data followed a distribution nor could it be transformed to fit into a distribution. In this work, the authors present an approach to evaluate on time performance of IR, given such “unruly” data.

Design/methodology/approach

An attempt is made to develop a lucid approach, given an unruly data. Initially, the authors plot a histogram using Scott’s method. Later, the authors use Taguchi’s quality loss function to assign weights to each of the bins in histogram. Weights to each of the bins are assigned based on the predefined rules. Finally, sigma level is computed by using weighted defect per million opportunities (DPMO) approach. In this paper, the authors discuss the proposed algorithm, an illustrative example with an emphasis on a class of IR.

Findings

Given the unique characteristic (unruly data) of arrival data of IR, the proposed methodology helps in quantifying it is on time performance. This method extends the conventional DPMO approach of computing the sigma level. The proposed method is validated using various data sets of different distributions. Further, this approach can be generalized and applied to data set of any distribution. Since distribution of the data is not the pre-requisite, the proposed approach can be applied to compare (and benchmark) data sets of different distributions. This methodology, thus, paves path to develop newer approaches in quantifying and benchmarking the sigma levels.

Research limitations/implications

In this manuscript, the authors present a case of Rajdhani Express trains, a class of IR. A practicing manager can use this approach to compare the performance of various classes of railways and benchmark their performance. Such an approach, with suitable modifications (if any) can be applied to evaluate performance in various service industries.

Originality/value

Usually, if the data are unruly, the sigma level is computed by usingad-hocmethods that may provide compromising solutions and/or inaccurate results. The developed methodology proposes a unique approach to quantify sigma level, given such an unruly nature of the data. This approach thus fills the long needed gap in addressing such situations. This approach can be applied in various similar situations. A case of IR is presented.
Improvement of the reliability of a dependent system under copula
Authors: Temraz Neama
Published: October 2018

Purpose

The purpose of this paper is to analyze a parallel system consisting of n dependent components with lifetimes following Weibull distribution. FGM Copula in multivariate case is used to generate the reliability function of the original system. A reduction method is introduced to improve system reliability. Other methods of hot, cold and warm duplication are established to improve system reliability. An application is introduced to show the results and compare between different improvement methods.

Design/methodology/approach

In this paper, a study of a parallel system consisting of n dependent and non-identical components is introduced. Reliability function of the original system is derived by using the concepts of copula, subject to Weibull distribution. Reliability function of the original system is improved according to reduction, hot duplication, warm and cold duplication methods. Reliability equivalence factors are introduced to compare between different system designs. Numerical illustration and real-time data application are discussed to show the results obtained in this paper.

Findings

Copulas can be used to model the reliability of systems with dependent units.

Originality/value

This paper is original. Improvement of the reliability of dependent systems is not discussed in literature. Copula is a useful tool to analyze the reliability of dependent systems. The introduced model is considered as a generalization of the models discussed in literature.
Impacts of ISO 9000 on Greek SMEs business performance
Authors: Kakouris Andreas P. , Sfakianaki Eleni
Published: October 2018

Purpose

The purpose of this paper is to explore the association between ISO 9000 certification and business performance for small-to-medium enterprises in the food and beverage (F&B) industry.

Design/methodology/approach

The research employed a qualitative approach based on case studies to investigate in depth how companies perceive ISO 9001. More specifically, four enterprises were examined, and a total of 26 semi-structured in-depth interviews were conducted with top and middle managers from the companies. Questions were validated by experts and through pilot interviews. In total, 45 documents of a broad range related to the quality management system were examined. Personal observation and non-structured consultation with personnel were also used to evaluate the possible impacts and livelihood outcomes.

Findings

Research findings showed that the certified companies in the F&B industry gain a number of both internal and external benefits, including: quality awareness, increased productivity, increased personnel participation and efficiency, improved image and penetration into new markets. Regarding the financial benefits of certification, the findings are not as convincing, as one company reported no financial benefits, and the rest reported that financial benefits are indirect and intangible. Conclusively, it can be said that SMEs that wish to pursue certification should certainly expect benefits.

Practical implications

Although many studies have concentrated on analyzing the impact of the implementation of ISO 9001 certification, there is still a clear need for research in specific sectors. Practicing managers and researchers will be able to examine findings in order to evaluate benefits and weaknesses from certification, thereby identifying and acting before and after certification.

Originality/value

Although the F&B industry has shown a great preference for the ISO 9000 standard and has adopted it extensively, scant empirical evidence has been recorded on the subject. This paper contributes to a better understanding of the benefits for implementing the ISO 9001 certification and to the analysis of its application to the ever-important F&B industry in Greece, a country whose economy is particularly supported by SMEs and has been severely hit by the economic crisis. Researchers will therefore further their knowledge, understand benefits but also acknowledge weaknesses.