bluuebunny/crossref_metadata_2025 huggingface dataset:
A CAPILLARY GC-MS ANALYSIS OF RESIDUAL ETHANESULFONATES IN TENELIGLIPTIN
Authors: M. Manivannan  , P. Parthiban  , P. Ilayaraja
Published: April 2023

The presence of residual sulfonate esters in drugs is potentially genotoxic impurities (PGIs), thus demanding a need for a specific method to quantify them in the drug as per regulatory authorities’ guidelines. Accordingly, a GC-MS procedure was optimized and proved for the assessment of ethyl ethanesulfonate (EES) and isopropyl ethanesulfonate (IPES) in the Teneligliptin drug. The detection (LOD) and quantification (LOQ) limit values of EES and IPES were 3.75 and 11.25 ppm, respectively. A linear relationship was observed between 11.25 and 56 ppm. The mean recoveries of EES and IPES were 102.65 and 102.21%. The method is precise, accurate, specific, and linear; thus it can be employed to measure the EES and IPES in Teneligliptin and other gliptins.
Schüler*innen beruflicher Schulen – eine polarisierte Zielgruppe? Projekterfahrungen aus dem ländlichen Raum Osthessens
Authors: Lachmann Paul
Published: April 2023

In diesem Beitrag werden zentrale Ergebnisse des Projekts „Gestern wie heute – Haltung zeigen!“ vorgestellt. Das Projekt ist als Reaktion auf die Präsenz der extremen Rechten im öffentlichen Raum, die Alltäglichkeit gruppenbezogener Menschenfeindlichkeit in Hessen sowie die schlechte Lage politischer Bildung an beruflichen Schulen entstanden. Einerseits versucht es, die Resilienz der einzelnen teilnehmenden Schüler*innen und ihr Bewusstsein für gemeinschaftliche Konfliktlösung zu stärken. Andererseits ist mit dem maßgeblich pädagogisch arbeitenden Projekt auch ein wissenschaftliches Interesse verbunden. Schüler*innen beruflicher Schulen (SbS) sind in Einstellungserhebungen selten vertreten. In Studien heißt es meist: Je geringer die formale Bildung, desto weniger stehen die Schüler*innen für demokratische Werte ein und stimmen eher extrem rechten Einstellungsmerkmalen zu. Dieser Beitrag versucht, anhand der Ergebnisse einer eigenen Einstellungserhebung sowie qualitativer Beobachtungen die Frage zu beantworten, ob diese Verallgemeinerungen auch auf die bisher unsichtbar gebliebene Schüler*innenschaft an beruflichen Schulen zutreffen. Im vorliegenden Projekt offenbaren sich strukturelle Benachteiligungen für SbS, zudem deuten sich konflikthafte Gleichzeitigkeiten in den Werthaltungen der Schüler*innen an.
The Application of Adjustable Magnetic Devices in Electric Power Systems
Authors: Gwóźdź Michał
Published: April 2023

This work represents a continuation of the research cycle on magnetic devices with adjustable parameter values. The work focuses on the possibility of using tunable magnetic devices in electrical power systems with adaptive features. The idea underlying this type of operation, which depends on interaction with magnetic fluxes, is a new approach to the design of magnetic elements. Suitable examples of adaptive electric power systems can act as devices for improving the quality of electricity. When used in compensators of reactive power or both reactive and distortion power, magnetic devices in the form of tuned inductors offer much wider possibilities for the compensation of both reactive and distortion power in electric systems, compared to ‘standard’ solutions, involving compensators based on inductors with fixed parameter values. Nevertheless, the application of the proposed device in electric systems such as these is only one example of its possible implementations in the area of electric power. In the work, the following issues are covered: an exemplary solution of an adaptive ‘passive’ compensator, rules for the operation of an adjustable magnetic device, and an investigation of the results from a laboratory model of an electric system based on this device.
Análise prototípica de professoras das classes regulares acerca da sala de recursos
Authors: Macedo Davinni da Silva , Gonzaga Luciano Luz
Published: April 2023

Esta pesquisa é parte integrante do Mestrado Profissional em Ensino de Ciências e Saúde, de uma Instituição do Ensino Superior do Estado do Rio de Janeiro, e visa identificar os principais cognemas de professoras da Educação Básica, de uma escola pública da região da Baixada Fluminense, no Estado do Rio de Janeiro, acerca da Sala de Recursos Multifuncionais. Ao grupo, foi aplicado um Teste de Evocação Livre de Palavras a partir do termo indutor “sala de recursos” e a análise foi realizada pelo software Evocation 2000. A Teoria das Representações Sociais de Moscovici (1961), foi o principal aporte teórico da pesquisa. Dessa forma, buscou-se detectar as possíveis crenças que professoras das classes regulares desenvolvem acerca da sala de recursos da unidade escolar em que atuam na tentativa da valorização dos saberes e opiniões destas profissionais em relação ao Atendimento Educacional Especializado (AEE) e pensar em possíveis estratégias que possam contribuir para um trabalho colaborativo entre as professoras das turmas regulares com as professoras da sala de recursos. Como resultados, a centralidade da representação revela que o ‘amor’ é a engrenagem para o funcionamento do espaço. Por outro lado, a periferia revela o caráter auxiliador e de zelo no atendimento aos estudantes com necessidades especiais.
PENGAJARAN-PEMBELAJARAN BAHAN SENI BAHASA: APLIKASI SEMANTIK INKUISITIF DAN TEORI RELEVANS
Authors: Bujang George Romiko , Subset Mary Fatimah
Published: April 2023

Kajian ini bertujuan untuk mengesan dan menjelaskan makna tersirat dalam bahan seni bahasa melalui pengaplikasian pendekatan semantik inkuisitif (SI) yang diperkenalkan oleh Nor Hashimah Jalaluddin (2014) dan digabungjalinkan dengan Teori Relevans (TR) yang diasaskan oleh Sperber & Wilson (1986, 1995).  Penyelidikan berbentuk kualitatif ini menggunakan kaedah analisis teks terhadap bahan seni bahasa yang terkandung dalam buku teks Bahasa Melayu Tahun Empat Sekolah Kebangsaan (SK). Kaedah pemerhatian turut dilakukan terhadap 10 orang pelajar Tahun Empat di Sekolah Kebangsaan Batu Luking yang terletak di daerah Kanowit, Sarawak yang menjadi responden kajian ini.  Hasil kajian mendapati bahawa bahan seni seperti sajak dapat mewujudkan persoalan-persoalan berbentuk kemahiran berfikir aras tinggi (KBAT) dalam kalangan pelajar. Selain itu, kajian ini juga mendapati bahawa makna tersirat yang dihajati penyajak dapat dikesan oleh para pelajar apabila analisis satu persatu pendekatan semantik inkuisitif dilakukan, bermula

dengan analisis semantik skrip, semantik resonans dan seterusnya semantik inkuisitif. Pengaplikasian teori Relevans pada tahap kedua analisis semantik resonans telah menunjukkan bahawa mata pelajaran bahasa Melayu dapat digabungjalinkan dengan pelbagai disiplin ilmu yang lain dan pembelajaran mata pelajaran ini menjadi lebih menarik dan bersifat multi-disiplin.  Kajian ini berupaya dijadikan sebagai sumber rujukan kepada para pengkaji, guru-guru bahasa dan pelajar sekolah khususnya dalam mempelajari dan menelusuri makna yang terkandung dalam bahan seni bahasa. Kajian ini telah mengetengahkan bukti saintifik terhadap ujaran yang digunakan dalam penghasilan sajak sebagai bahan seni bahasa.
Nâng cao hiệu quả bảo mật cho hệt hống tên miền
Authors: Tân Trần Minh , Tam Nguyễn Văn
Published: April 2023

Domain  Name  Server  (DNS)  system,  a root  source  providing  answers  with  IP  addresses  forany request for domain names, is regarded as the most important  part  of  Internet.  DNS  system  also  plays  avery  important  part  of  cryptography  analytic infrastructure  of  Internet.  Any  change  made  to  DNS system  can  make  the  system  fall  into  malfunction, boosting  complexity  levels  in  dealing  with  triggered issues  [2,11].  Therefore,  security  for  DNS  is  a  vital must.  For  the  time  being,  RSA  algorithm  [6,12]  has become  the  de  factor  standard  for  DNS  security. However,  RSA  requires  a  longer  key  length  of  more than  1000  bits  [10,15],  affecting  performance efficiency  of  DNS  system.  Hence,  elliptic  curve cryptography  or  ECC  is  regarded  as  an  alternative mechanism for implementing public-key cryptography.The  ECC  is  expected  to  be  used  not  only  in  new generation  mobile  devices  [13]  but  also  in  DNS system in the near future as ECC requires shorter key length than RSA but providing the same security level. This  paper  focuses  on  introducing  ECC  and  new findings  related  to  this  mechanism  such  as  key  pairgeneration  algorithms,  key  transfer,  encryption  anddecryption in ECC, as well as findings of the trialon the  Vietnam  national  domain  name  system  dot  VN; these  findings  aims  to  apply  for  certification  domain name  data  transfer  for  the  DNS  system  of  a  country and compare with the same method in RSA algorithm
Numerical and Analytical Study of a Geo-exchange Borehole Using Conventional Grout and Bentonite-Based Backfilling Material
Authors: Bayomy Ayman M. , wang jun , Dworkin Seth
Published: April 2023

Ground source heat pumps (GSHP) have been used in various types of residential and commercial buildings due to their high efficiency. Numerical models are useful to predict the overall performance and ground temperature response of these systems. This paper presents a hybrid model that contains a modified finite element model and an analytical solution for a single conventional vertical borehole system. In this modified finite element model, turbulent heat transfer equations were solved for the ground heat exchanger and the actual building load variation and heat pump performance variation were considered. The present model was then used to explore an emerging geo-exchange technology, which involves the use of a bentonite slurry enhanced with graphite flakes in the vicinity of a borehole heat exchanger. The results revealed slight increases in the mean average ground temperature in the vicinity of the borehole by 1.1°C over 4 years. Furthermore, the analytical solution of the ground temperature response was in good agreement with the results obtained using the finite element model within a maximum relative error of 3% (0.5°C). The results revealed that the 40 m depth bentonite-based borehole achieved better performance than the conventional design by 5% to 13% in the monthly average COP.
THE EFFECTIVENESS OF ERGONOMICS TECHNIQUES ON THE ABILITY TO OVERCOME MUSCULOSKELETAL DISORDER (MsDs) COMPLAINTS AMONG TAILORS IN BENGKULU CITY AND JAKARTA CITY 2019
Authors: Mulyati Sri , Prabowo Kuat , Kermelita Deri
Published: April 2023

Ergonomics is essential to study because it can avoid fatigue and muscle injuries affecting employee performance. One of the diseases caused by ergonomics is the complaint of MsDs. There is an effect of the ergonomic technique on the ability to reduce MsDs complaints in tailors in Bengkulu and Jakarta. This research to know the ergonomic of the sewers and to identify the complains MsDs before and after intervention and the influence of the true ergonomic intervention toward the compalains of MsDs. The research uses a quantitative survey design with a quasi-experimental approach to non-randomized control group pre-test-post-testing (training intervention group respondents using a module on ergonomic techniques when sewing) and observing ergonomic practices when sewing. Data analysis used univariate and bivariate. Research results in ergonomic variables: Bengkulu City before treatment mean 7.55 after treatment 12.05. The city of Jakarta before the treatment means 7.50. After treatment, the mean is 11.0. MsDs complaint variable: Bengkulu city before treatment mean 63.8 and after treatment mean 45.3. The city of Jakarta before treatment means 64.82 after treatment means 45.3. Suggestions are expected that the tailors in the treatment group use a module that the tailor has received to be a guide in sewing work to minimize MsDs complaints.
IDENTIFICATION OF CALAMANSI FRUIT PEEL ESSENTIAL OIL COMPONENTS FROM BENGKULU USING GC-MS
Authors: Purnama Yetti , Dewiani Kurnia , Rahmawati Suci , Yusanti Linda , Fitriani Novri , Sunaryo Merki Aliyadi , Yulyani Linda
Published: April 2023

Calamansi orange (Citrofortunella microcarpa) is one of the citrus groups that have been cultivated in Bengkulu Province. Calamansi oranges have a distinctive aroma from the volatile oil components found in the skin of the fruit. This study aimed to identify the components of Bengkulu calamansi peel essential oil using GC-MS. The essential oil of calamansi fruit peel was obtained by steam distillation method using vacuum distillation. The essential oil yield obtained was 0.36%. The results of the examination of essential oils using GC-MS showed that there were 6 main compounds. they are 3-carane, Cyclopentanone, 2-(-methyl propyl), Cychexanol, 2methyl-5-(1-methylethenyl), Decanal, L-alpha-Terpineol and D-Crvone.
THE EFFECT OF GREEN BEAN JUICE AND PUDDING RED GUAVA ON THE ENHANCEMENT OF HEMOGLOBIN LEVELS IN ADOLESCENT GIRLS
Authors: Maharani Ridhola , Maigoda Tonny Cortis , Pravita Ayu
Published: April 2023

Adolescent girls are at risk of developing anemia because they have menstruation every month. Prevention of anemia by consuming foods that are high in iron and foods that help the absorption process can increase the hemoglobin levels of adolescent girls. This purpose of this study was  to determine the effect of consuming green bean juice and red guava pudding on the increase in hemoglobin levels of adolescent girls. This type of research used in this study was an experiment with a pre-test and post-test design. The  sample in this study was 21 people with random sampling technique which was divided into three groups. The intervention was carried out for 7 days. Data analysis used paired sample t-test.  The average increase after the intervention of the combination of red guava pudding and green beans was 3.6 g/dl with  p<0.05 . The average increase after the intervention of the green bean extract treatment group was 2.2 g/dl with  p< 0.05. While the of jelly plain group (control) only increased by 0.02 g /dl with  p > 0,05 . In conclusion, this study showed that there was an effect of giving a combination of red guava pudding and green beans   to increase hemoglobin levels. It was known that giving green bean juice to increase hemoglobin levels. However, there was no effect of giving agar (Control group) in increasing hemoglobin levels
The Effect of Internal Marketing on Organizational Citizenship Behavior
Authors: Adil Mahmood Alkhafagi Yasir
Published: April 2023

The aim of this paper is to determine the effect of internal marketing through three dimensions: vision, development, and reward - on organizational citizenship behavior in three private universities in Iraq. Organizations’ view of their members as internal customers could be made them more realistic in dealing with the reasons for leaving and going to other organizations. This can promote business organizations to build an organizational environment that contributes to making the organization look like the homeland of those workers. The research method is descriptive and analytical. The tool for data collection was the questionnaire. Statistical software (SPSS V.23 and AMOS V.23) was used to analyze the data. The research sample was randomly selected and consisted of 290 faculty members. The results of the research indicated that there is a positive effect of the independent variable “internal marketing” on the dependent variable “organizational citizenship behavior”. Also, the dimension of development has the most impact on organizational citizenship behavior, then comes the reward, and the vision, respectively. The research highlights the level of variables and the nature of the relationships between them in the private higher education sector in the Iraqi environment.

 

 

Paper type: Research paper
EVALUACIÓN DE LA VIABILIDAD Y RENTABILIDAD DE UN PROYECTO DE INVERSIÓN CON FONDOS PÚBLICOS PARA LA FABRICACIÓN DE TELAS UTILIZADAS PARA LA CONFECCIÓN DE UNIFORMES ESCOLARES GRATUITOS OTORGADOS POR LOS AYUNTAMIENTOS DE LA ZONA METROPOLITANA DE GUADALAJARA
Authors: Arroyo Martínez Simona
Published: April 2023

Este trabajo de investigación tiene como objetivo evaluar proyectos de in­versión con fondos públicos considerando los beneficios privados y los beneficios sociales y económicos de la región. La metodología utilizada fue mediante el caso de estudio, eligiendo una empresa con experiencia en la industria textil en Jalisco. Siendo su infraestructura tecnológica y capital humano los aspectos más relevantes que garanticen un proceso integral de producción de telas (teñido, urdido, tejido y acabado), lo que permite ex­plotar sus economías de escala, obteniendo mayores beneficios. Los resul­tados obtenidos mostraron que el nivel óptimo de producción es de 80% (2.4 millones de metros lineales de telas), con una tasa interna de retorno del 70.19% y una utilidad neta del $162’787,389.95, lo que representa un margen de utilidad de 33.41% en el primer año. Además, comprobamos que los recursos gubernamentales asignados a este tipo de proyectos gene­ran beneficios sociales y económicos por encima de los beneficios privados. Si el proyecto es financiado con recursos públicos, significa que por cada peso que asigne la Secretaría de Economía, éste será retornado a la econo­mía en 26 pesos por la generación de empleos directos e indirectos.
INTERVENCIONES DIDÁCTICAS PARA EL DESARROLLO DE LA MOTRICIDAD FINA EN LA FORMACIÓN DEL ODONTÓLOGO
Authors: Abraham Peñaloza Patricia , Chávez Rivera Rubén
Published: April 2023

En esta investigación se identificó la deficiencia en motricidad fina de los estudiantes que cursan la licenciatura de Odontología, basado en la fisio­logía de los músculos de la mano e identificando su falta de desarrollo. En este sentido, inicia con un diagnóstico, identificando la categoría de motricidad; del cual se establecieron las subcategorías, instituyéndose un plan de intervención de reeducación motriz, mediante la ejercitación de los músculos intrínsecos de la mano. De modo que la investigación es de corte cualitativo y con un enfoque interpretativo hermenéutico y fe-nomenológico. Así pues, se han diseñaron estrategias de aprendizaje ante la inquietud de apoyar de forma diferente la formación integral de los estudiantes. Consecuentemente, con la aplicación de intervenciones di­dácticas se obtuvieron resultados favorables, pues los músculos lograron el desarrollo y secuencialmente se vio reflejado el desempeño en la ejecución de procedimientos dentales, a diferencias con quienes no se les aplicó la metodología. El desarrollo de las habilidades motrices aumentará la con­fianza del estudiante en sí mismo al estar trabajando
MODELO DE CORRECCIÓN DE ERROR PARA LA TRANSMISIÓN DE PRECIOS DEL FRIJOL, 2003-2017
Authors: Morales Ventura Ana Gabriela , González Pérez José Manuel
Published: April 2023

El presente trabajo estudia la importancia del frijol y su precio como una de las leguminosas de mayor contribución en el valor de la producción agrícola. Para ello, se recurre al análisis de cointegración con la finalidad de realizar un Modelo de Corrección de Error (MCE) que permita medir el incremento en el precio inicial desde su producción, hasta el precio final cuando llega al consumidor. El modelo se basará en los datos obtenidos en un periodo de cotorce años, comprendidos de 2003 a 2017, con lo que se pretende determinar el aumento de precio explicado por cuestiones de comercialización o distorsiones de mercado, y no por incrementos en los costos de producción. En el segundo apartado se expone el método del modelo econométrico identificando las pruebas más relevantes. En la tercera parte se presenta la aplicación del modelo con información tomada del Instituto Nacional de Estadística y Geografía (INEGI), para el periodo 2003-2017. Y finalmente se presentan las conclusiones.
RECURSOS HUMANOS Y POLÍTICA EDUCATIVA PARA LA GESTIÓN AMBIENTAL
Authors: Castillo Girón Víctor Manuel , Marina Antoine Marva Esther , Ayala Ramírez Suhey
Published: April 2023

La política pública ambiental mexicana además de añeja es multifacética. Entre sus expresiones destaca la creación de Áreas Naturales Protegidas (ANP) que, aunque subyacen en un fuerte bagaje normativo, tienen ciertas tareas pendientes como la ausencia de medidas orientadas a la formación de recursos humanos para su gestión. Teniendo como referencia tres ANP ubicadas en Jalisco y administradas por el gobierno estatal, en este trabajo se analizan los posibles efectos vinculados con dicha omisión así como las áreas de oportunidad para potenciar su desarrollo. Los datos provienen esencialmente de la observación directa de sus procesos funcionales, así como de entrevistas a diversos funcionarios estatales y, particularmente, a los directores y ex directores de esas ANP. Concluimos que los procesos de gestión se sustentan más en juicios de valor de los directores en turno que en programas cimentados en la administración estratégica desde una visión holística correspondiente con el entorno político-educativo.
LA RESILIENCIA EN UN MODELO INTEGRADOR ANTE LA EXISTENCIA DE ESCENARIOS PATERNALISTAS EN EL PROGRAMA TUTORIAL DE ESTUDIANTES DE LA FCA-UN DE LA UADEC
Authors: González Guajardo Jesús Emilio , Zúñiga Corte Juan Hermilo , Aguillon Robles Jesús , Jiménez González Valeria Anahi
Published: April 2023

El estudio se desarrolló con un objetivo general: determinar si existen con­textos paternalistas en el programa de tutoría para los estudiantes de la Fa­cultad de Contabilidad y Administración Unidad Norte de la Universidad Autónoma de Coahuila con base en los siete pilares de la resiliencia de Wo-llin y Wollin y en los indicadores tutoriales con mayor impacto en el com­portamiento. La investigación es exploratoria, con un enfoque cualitativo y cuantitativo, por lo que se considera de tipo mixto; una población de 628 alumnos con tutor, determina una muestra de 243 con un nivel de confianza del 95% y un margen de error del 5%; se empleó el programa estadístico SPSS 21.0 y se determina la fiabilidad de la muestra con un resultado de .772 para el instrumento mediante el empleo del alfa de Cronbach. Entre los principales resultados obtenidos ee pueden mencionar que de un total de 17 variables, 6 (35.39%), se encuentran con actuaciones favorables; las restantes 11 variables (64.71%) de ellos, 8 tienen una fuerte inclinación hacia la escala favorable; Ninguno aparece en el rango de muy desfavorable. Se concluye con la afirmación de que se pueden descartar escenarios paternalistas.
EL DESEMPLEO EN MÉXICO DURANTE EL PERIODO 2000 – 2017: UN MODELO EMPÍRICO
Authors: Arroyo Martínez Simona , Ortega Ovalle Luis Gerardo
Published: April 2023

El objetivo del estudio es evaluar la inversión, la educación y el salario para determinar su impacto en la tasa de desempleo en México, durante el periodo 2000-2017. En julio del 2018, la tasa de desempleo abierto en México fue del 3.47 por ciento. Algunos autores plantean que bajas tasas de desempleo obedecen a que: 1) La Población Económicamente Abierta (PEA), no incrementa debido a la migración fuera del país; 2) Considerar que una persona está ocupada aunque trabaje un día a la semana. La inver­sión, el salario, Producto Interno Bruto (PIB) y la educación son variables que inciden en la tasa de desempleo. Por lo que diseñamos un modelo econométrico de regresión lineal estocástico para comprobar las hipótesis. Los hallazgos mostraron que la inversión influye en la tasa de desempleo de manera significativa, al igual que la educación, mientras el salario tiene un impacto poco significativo en la tasa de desempleo.
IMPACTO DEL LIDERAZGO TRANSFORMACIONAL EN LAS PEQUEÑAS EMPRESAS
Authors: López Saldaña Cristina del Pilar , Peña Cárdenas Maricela Carolina , Chávez Macías Adriana Guadalupe , Rivera Flores Karen Yaneth , Zamora de los Santos Fátima Guadalupe
Published: April 2023

El liderazgo normalmente se relaciona con el funcionamiento de una or­ganización, siendo un elemento esencial para que una empresa alcance con éxito sus resultados. El objetivo de esta investigación consistió en analizar el impacto del liderazgo transformacional en la gestión de las pequeñas empresas del sector comercial de Monclova, Coahuila, México. La meto­dología empleada corresponde a una investigación de campo tipo cuanti­tativa, descriptiva y transversal. Los resultados demuestran que el liderazgo transformacional dentro de las pequeñas empresas tiene un impacto posi­tivo. Lo que permite concluir que utilizar este tipo de liderazgo representa un factor predominante en el desarrollo de las organizaciones ya que diri­gen su gestión a la búsqueda de resultados óptimos.
CELDAS FOTOVOLTAICAS EN EL DESARROLLO ECONÓMICO EN LA SUBJETIVIDAD SOCIAL EN CLIMA EXTREMO: MÉXICO
Authors: Chávez Rivera Rubén , Ramos Sánchez Jesús Ricardo , Alcaraz Vera Jorge Víctor
Published: April 2023

El objetivo es conocer el desarrollo económico y social con el uso de la tecnología de celdas fotovoltaicas para satisfacer el ahorro y el bienestar de las familias con clima extremo en México. Considerando el incoveniente de las familias de escasos recursos para invertir en celdas fotovoltaicas en estos tiempos el estudio se enfoca sobre clase social media-alta y alta. Se interviene la forma de medición de factores que inciden en el desarrollo regional en dos variables latentes: el ahorro económico con el uso de cel­das fotovoltaicas y su consecuente satisfacción de bienestar social en clima extremo. La medición de las variables se hace con la propuesta del modelo de ecuaciones estructurales (SEM) conjugado con lógica difusa (Mamda-ni-MatLab), la cual permita encontrar valores no observados a través de los indicadores de tipo cualitativos lo que permite flexibilidad de generar intervalos de confianza que puedan dar respuesta a variables endógenas de una manera cuantitativa.
EL CRECIMIENTO DEL COMERCIO INTERNACIONAL A PARTIR DE LAS CONCEPCIONES DE PAUL KRUGMAN
Authors: Chamú Nicanor Félix , Marín Leyva René Augusto
Published: April 2023

El objetivo del presente artículo es analizar el crecimiento del comercio internacional a partir de las concepciones del economista Paul Krugman. De acuerdo con este autor, el comercio internacional (mercancías y ser­vicios comerciales) está determinado fundamentalmente por economías de escala en mercados imperfectos. Las ganancias del comercio ocurrirán, incluso entre países con gustos, tecnologías y dotación de factores idénti­cos. A partir del análisis descriptivo del comercio internacional en el pe­riodo 2008-2018, se concluye que el comercio ha tenido un importante crecimiento en dicho periodo, excepto en el año 2009 debido a la crisis financiera y económica mundial. En el año 2018, el comercio de mercan­cías tuvo una participación mayor (78%) en el comercio internacional con respecto a los servicios comerciales transados (22%). Aunque cabe señalar que, en los últimos 10 años, los servicios comerciales han tenido un mayor crecimiento, sobre todo impulsado por las tecnologías de la información y comunicaciones (TIC).
Gleymda foreldrið: Foreldraútilokun frá sjónarhóli útsetta foreldrisins
Authors: Poustie Clare , Matthewson Mandy , Balmer Sian
Published: April 2023

Rannsóknin beindist að upplifun útsettra foreldra af foreldraútilokun og útilokandi hegðun. Eitt hundrað tuttugu og sex útsettir foreldrar svöruðu opinni spurningu í lok netkönnunar og sögðu frá reynslu sinni. Stuðst var við þemagreiningu Braun og Clarke (2006) til að greina þemu í gögnunum. Greind voru sex þemu sem lýsa reynslu útsettra foreldra af foreldraútilokun og útilokandi hegðun. Útsettir foreldrar lýstu því hvernig þeir upplifa líkamlega og tilfinningalega viðskilnað við börn sín, og þeir lýstu hvernig afskipti þeirra af „kerfum“ eins og réttarkerfi og barnaverndarkerfi taki af þeim toll, fjárhagslega og tilfinningalega. Foreldrarnir lýstu vanlíðan og áhyggjum af andlegri velferð barna sinna. Útsettir foreldrar litu á útilokandi hegðun sem birtingarmynd heimilisofbeldis. Útsettir foreldrar sýndu einnig fram á virka spjörunarhegðun (e. coping behavior). Niðurstaðan er sú að þörf sé á frekari rannsóknum, svo hægt sé að öðlast dýpri skilning á foreldraútilokun. Geðheilbrigðisstarfsfólk og lögfræðingar þurfa að vinna saman, svo hægt sé að veita útsettum foreldrum viðunandi stuðning.
Tradução E Adaptação Transcultural Do Índice De Vulnerabilidade Clínico-Funcional (Ivcf-20) Para Português Europeu
Authors: Pinho Ana Maria , Morais Ana Paula
Published: April 2023

Introdução: A avaliação multidimensional clínica e funcional é fundamental na intervenção adequada e personalizada da pessoa idosa. O Índice de Vulnerabilidade Clínico Funcional (IVCF-20) é um instrumento simples, que contempla aspetos multidimensionais da saúde do idoso. Este estudo tem como objetivo traduzir e adaptar transculturalmente o IVCF-20.
Metodologia: No estudo foi realizada a tradução da escala original, retrotradução e validade de conteúdo (painel de peritos e 2 pessoas idosas). Com o pré-teste emerge a versão final do IVCF-20 em português europeu. Ao longo do processo houve envolvimento dos autores da escala original.
Resultados: A equivalência linguística e semântica decorreu de forma clara e simples. No painel de peritos instigaram-se alterações em 12 dos 20 itens: 7 itens com a concordância de todos (100%) e 5 itens com 75%. No pré-teste emerge a necessidade da alteração de um termo, obtendo-se a versão do IVCF-20 em português europeu.
Discussão: A inclusão de pessoas idosas no processo tornou-se muito vantajosa. Procedeu-se à alteração do intervalo da classificação da idade, de acordo com a definição da OMS e ONU, foi considerado o intervalo de 65-74 anos em vez de 60-74 anos (escala original). Na aplicação do pré-teste verificou-se ligeira dificuldade na compreensão das questões mais extensas (Q18 e Q19) e na interpretação da expressão “saúde normal”.
Conclusão: A versão portuguesa do IVFC-20 é um instrumento de fácil compreensão, com linguagem simples e pode ser usado com confiança na prática clínica. Pretende-se de seguida, a realização do estudo psicométrico para assegurar a sua validação.
Anaphylaxis to the Pfizer or BioNTech COVID-19 Vaccine with Positive Polyethylene Glycol Skin-Prick Test in Brazil
Authors: Werber-Bandeira Luiz , Braga Bruno , Bandeira Thiago , Almeida Elisa , Bandeira Isabela , Sabra Aderbal
Published: April 2023

A 56-year-old male patient attended at the Medicine Allergy Section with a current history of itchy red spots on the body reported that a few hours after receiving the the Pfizer/ BioNTech messenger RNA (mRNA) COVID-19 vaccine, started with red and pruritic lesions. On physical examination, the patient did not show any considerable alteration. Under dermatological examination diffuse red urticarial lesions were present in the thoracic region. A biopsy of the urticarial lesion for histological analysis and epicutaneous-prick test (SPT) with polyethylene glycol (PEG) 335, 600, 3350 and 6000 with reading after 15 minutes were performed. Urticaria biopsy showed eosinophilic and lymphocytic infiltrate and SPT was positive for PEG 6000 (wheal size 5mm). The patient was treated with an antihistamine and corticosteroid 30mg per day for 5 days. Upon returning, the lesions had disappeared. PEG allergy is not so common and it seems to occur to higher molecular weight PEGs or higher concentrations. However, since the use of this molecule as an excipient in mRNA vaccines have no precedent before COVID-19, not much information was available and anaphylaxis reactions to mRNA vaccine from Pfizer/BioNTech COVID-19 induced or supposedly induced by PEG have been reported.
Spontaneously Conceived Quadruplet with Three Viable Babies & A Papyraceous Fetus: A Case Report
Authors: I.J Onyekpa , B.U Odugu , I.I Okafor , C Nevo , C.A Omeke , K Ortuanya , C Ofonere , V Udeozor , N Ezeora , B.C Nwachukwu , C.S Onyekpa
Published: April 2023

Background: High order multiple gestations are an uncommon occurrence. The incidence of multiple gestation continues to decrease as the number of fetuses increase as calculated using Hellin’s rule: incidence = 1:80n-1 births, where n is the number of fetuses. Thus, the expected incidence of quadruplets is estimated at 1 in 512,000 births. All these have changed with the advent of reproductive technology. However, the occurrence of quadruplets as a natural process has remained rare globally. Objective: To report a case of a successful spontaneously conceived quadruplet with the death of one of the fetuses and delivery of 3 live fetuses and a twin papyraceous fetus at the 36th week of gestation. Methods: We report a case of a 28-year-old para-2 woman who had a spontaneous conception resulting in a quadruplet. She had an ultrasound diagnosis of death of one of the fetuses at 25 weeks of gestation. She was admitted twice in the course of the pregnancy and subsequently delivered at the 35th week of gestation. Results: A successful caesarean delivery of 2 fem ales and 1 male with a male papyraceous fetus.
Rhabdomyosarcoma-Like and Non-Rhabdomyosarcoma-Like in Children: Assessment of Outcomes in Combination Cancer Therapy
Authors: Jazdon Miłosz , Kuc Dominika , Radziejewska Olga , Singh Swati , Derwich Katarzyna
Published: April 2023

Soft tissue sarcomas (STS) are rare malignant neoplasms, accounting for approximately 7-8% of childhood cancers. The 5-year survival rate varies from 15-90% depending on the severity of the disease. The purpose of our study was to assess the therapeutic results of patients who received combined treatment, according to CWS Protocols implemented at the Department of Pediatric Oncology, Hematology and Transplantology (DPOHT) in Poznan (2007: 2017). The study group consisted of 29 children, although the final analysis of treatment outcomes was completed in 25 children, 18 (72%) boys and 7 (28%) girls. Combined treatment according to the regimens of VAIA III, CEVAIA, O-TIE, radiotherapy and surgery was applied. After first-line treatment, 17/25 (68%) patients achieved remission and 7/25 (28%) died due to disease progression without achieving remission. One child (4%) received palliative care with disease progression. In 3/17 (18%) children, the disease relapsed. The pOS for the RMS-like group is 0.530 and the non-RMS-like group is 0.621. The pEFS for the RMS-like group is 0.578 and the non-RMS group is 0.505. The 5-year survival probability of RMS-like and non-RMS-like patients, despite intensive treatment, is lower than other childhood cancers. In the study group, treatment failures were mainly due to treatment resistance.
OPTIMASI PEMBUATAN SERBUK INSTAN DARI BUAH JERUK KEPROK (Citri reticulata) DENGAN METODE KRISTALISASI
Authors: Monica Eva , Setiyawan Muhammad , Afthoni Muhammad Hilmi , Ando Rollando
Published: April 2023

Jeruk keprok (Citri reticulata) atau sering juga disebut dengan Tangerang yaitu salah satu jenis jeruk yang paling banyak digemari. Buah jeruk keprok (cetus reticulata) adalah salah satu sumber yang kaya vitamin C dan mengandung asam sitrat. Pada perkembangan jaman banyak berbagai olahan produk pangan dalam berbentuk minuman serbuk instan yang banyak disukai oleh berbagai masyarakat. Pada penelitian ini bertujuan mengetahui formulasi yang optimal, karakteristik mutu dan stabilitas pada serbuk instan dari buah jeruk keprok (citra reticulata).

Pada penelitian ini menggunakan metode kristalisasi. Penelitian dilakukan pada bulan Juli - September 2022 dengan mendapatkan sampel di desa Dau Kabupaten Malang. Pada penelitian ini, dilakukan pengujian terhadap 3 formulasi sediaan serbuk instan dari buah jeruk keprok (Citrus reticulata) dengan uji karakteristik dan stabilitas yang terdiri dari uji mikrobiologi, organoleptik, hedonik, kadar air, laju alir, kadar vitamin C.

Hasil dan kesimpulan penelitian formulasi 1 dengan perbandingan air jeruk dan gula sebesar 1:1 dipilih sebagai formula yang optimal dengan hasil uji hedonik tertinggi dari 40 responden serta memenuhi persyaratan karakteristik mutu dan mempunyai kadar vitamin C sebesar 42,3%. Saran pada penelitian selanjutnya perlu diteliti dalam mengoptimasi sediaan serbuk instan dalam beberapa pengujian yaitu uji kadar vitamin C dan uji laju alir.
DNA contamination and taxonomic diversity hinder eDNA research on freshwater stingray species: Comment on Lim & Then (2022)
Authors: Alshari NFMAH , Adnan MHIB , Jamaluddin JAF , Lavoué S , Nor SAM
Published: April 2023

Recently, Lim & Then (2022; Endang Species Res 48:43-50) used an environmental DNA (eDNA) PCR-based method for detecting the presence of an endangered species of freshwater stingray, Fluvitrygon kittipongi (Dasyatidae), in the Pahang River basin, east Peninsular Malaysia. For that, they designed a species-specific pair of primers to amplify a 196 base pair (bp) fragment of the cytochrome c oxidase I (COI) gene. Lim & Then (2022) reported positive detection of this species along an upstream stretch of the Pahang River during the inter-monsoon and the southwest monsoon seasons, with the PCR-amplified eDNA sequences identical to the reference COI sequences of F. kittipongi collected from the Perak River basin, west Peninsular Malaysia. Here, we argue that such positive results are likely the consequence of a DNA contamination because the 196 bp COI fragments of F. kittipongi from the Pahang River and the Perak River differ from each other by 4 nucleotide substitutions. The source of contamination in Lim & Then (2022) could have been the Perak samples the authors handled to develop the primers. We also briefly discuss the potential impact of the presumed co-occurrence of freshwater stingrays of the genus Fluvitrygon in the Pahang River on the specificity of the F. kittipongi-specific primers designed by Lim & Then (2022).
Condition, size, and winter duration affect winter survival probability of juvenile Atlantic cod Gadus morhua in a coastal subarctic ecosystem
Authors: Geissinger EA , Bloom CR , Gregory RS , Laurel BJ , Snelgrove PVR
Published: April 2023

Juvenile Atlantic cod Gadus morhua in coastal Newfoundland, Canada, settle in nearshore habitats in 3-6 pulsed events each year, from mid-summer to early winter, creating a broad size range of age-0 fish within each year-class, with potentially different survival trajectories entering their first winter. We hypothesized that early-arriving pulses, high autumn body condition, and low winter severity would contribute to high first-winter survival of age-0 cod. To test these hypotheses, we examined juvenile cod catch data, archived samples, and winter temperature records to determine the impact of winter duration, body condition, and settlement time on winter survival from 2001 to 2019. Settlement pulse, pre-winter condition, and winter duration had an interactive effect on survival. Fish condition did not vary across pulses within a given year-class, but we observed improved winter survival during long winters when body condition was high, with highest survival among the larger, early-arriving pulses of fish. Late-arriving pulses of fish were small-sized before winter onset, but these pulses unexpectedly survived better than pulses settling earlier in the season during short winters when body condition was high. However, all settlement pulses had a survival advantage when settlement occurred earlier on average (associated with warmer autumns), suggesting that increased growth and size within a pulse can also contribute to overwintering success. Our findings challenge some assumptions of overwintering ecology (e.g. ‘bigger is better’, low temperature stress) but illustrate the importance of cohort effects for overwintering survival in a sub-arctic marine ecosystem in a changing climate.
The role of dorsal columns pathway in visceral pain
Authors: Paleček J
Published: April 2023

Traditionally, the dorsal column-medial lemniscus system has been viewed as a pathway not involved in pain perception. However, recent clinical and experimental studies have provided compelling evidence that implicates an important role of the dorsal column pathway in relaying visceral nociceptive information. Several clinical studies have shown that a small lesion that interrupts fibers of the dorsal columns (DC) that ascend close to the midline of the spinal cord significantly relieves pain and decreases analgesic requirements in patients suffering from cancer originating in visceral organs. Behavioral, electrophysiological and immunohistochemical methods used under experimental situations in animals showed that DC lesion lead to decreased activation of thalamic and gracile neurons by visceral stimuli, suppressed inhibition of exploratory activity induced by visceral noxious stimulation and prevented potentiation of visceromotor reflex evoked by colorectal distention under inflammatory conditions. Whereas the surgical lesion of the DC tract has proven to be clinically successful, a pharmacological approach would be a better strategy to block this pathway and thus to improve visceral pain conditions under less dramatic circumstances than cancer pain. Our finding that PSDC neurons start to express receptors for substance P after colon inflammation suggests new targets for the development of pharmacological strategies for the control of visceral pain.
OBEYING KYAI; The Tradition of Santri’s Mariage in Maqāsid Sharī'ah Perspective
Authors: Masruh Ahmad , Zahro Ahmad
Published: April 2023

This article is the result of a qualitative field research. The research location is at the At-Tahdzib Islamic Boarding School Rejoagung Ngoro Jombang. The direction of the discussion in this article is how to place the marriage tradition following the Kyai within the framework of maqasid marriage and maqasid shariah. The researcher uses maqasid al-nikah and maqasid shariah theory in explaining the position of the marriage tradition following the Kyai, because the maqasid al-nikah and maqasid shariah theories. The researcher argues that the marriage tradition following the Kyai provides advocacy for the protection of the bride and groom in achieving the goals of marriage and the goals of the Shari'a that arise from marriage

Keywords: marriage is obedient to the kyai, maqasid shariah.

 

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Long-term results comparison after anterior cervical discectomy with BGS-7 spacer (NOVOMAX®-C) and allograft spacer: A prospective observational study
Authors: Ryu Seungjun , Ryu Dal-Sung , Kim Keun-Su
Published: April 2023

Introduction: In an anterior cervical discectomy and fusion (ACDF), various types of graft materials including autograft, allograft, and synthetic graft have been used to achieve adequate spinal fusion. Allograft spacer is mainly used in cervical fusion, especially in the anterior approach. The synthetic bone graft material BGS-7(CaO-SiO2-P2O5-B2O3, bioactive Glass-Ceramics) can bind with surrounding bone tissue by forming a hydroxyapatite layer bone bridge, leading to faster graft osseointegration. This study was conducted to compare long-term clinical outcome of BGS-7 spacer and allograft spacer for anterior cervical discectomy and fusion surgery.

Materials and Methods: From September 2014 to December 2016, Consecutive anterior cervical discectomy and fusion surgeries using a BGS-7 spacer (N = 18) and Allograft spacer (N = 26) were compared for postoperative clinical outcomes. Radiologic assessments were performed, and Instrumental failure, including breakage, cage migration, subsidence were observed and Fusion status were analyzed. Finite element analysis was performed for simulating mechanical stress between the vertebral body and implant. Clinical outcomes were evaluated using neck VAS, NDI, and JOA on the patient’s final follow-up visits.

Results: Among the 44 patients who underwent an anterior cervical discectomy and fusion surgery using the BGS-7 spacer and Allograft spacer, there were 30 men and 14 women. The average age at the operation was 47.69 ± 10.49 in allograft spacer and 51.67 ± 11.03 in BGS-7 spacer. The mean follow-up period was 89.18 ± 5.44 months. Twenty three (88.46%) patients in allograft spacer and 20(100%) patients in BGS-7 spacer were demonstrated radiologic evidence of interbody fusion in last OPD, which accounts for fusion grade 4 or 5. Peak stresses were 343.85 MPa in allograft spacer, and 132.55 MPa in BGS-7 spacer. Long-term clinical outcomes including neck VAS, NDI, and JOA didn’t show statistical differences between the two groups. There were no adverse events related to the BGS-7 spacer.10.3389/fbioe.2023.110046.

Conclusion: The BGS-7 spacer demonstrated reliability as a spacer in anterior cervical discectomy and fusionF surgery without instrumental failure. Early stabilization with a bony bridge formation was observed at the intermediate follow-up period, and the long-term clinical outcome was favorable at more than 60 months after surgery without any adverse events. Thus, the BGS-7 spacer is a safe and effective alternative to the allograft spacer in anterior cervical discectomy and fusion surgery.