bluuebunny/crossref_metadata_2025 huggingface dataset:
Student science club — an important link in the structure of higher medical education
Authors: Ilyenko L. I. , Fedulaev Yu. N. , Orlova N. V. , Pinchuk T. V. , Spiryakina Ya. G.
Published: April 2023

Aim. Studying the motivation of students to participate in the work of student science clubs (SSCs) and determining the most attractive modes of work for students.

Material and methods. The study involved 28 postgraduate students and 129 thirdand fourth-year students of the pediatric faculty of the Pirogov National Research Medical University. A snapshot survey was conducted with subsequent analysis and statistical processing of the data obtained.

Results. The results showed that 45% of the students surveyed are active SSC participants. The most interesting for students are clinical disciplines (pediatrics, therapy, surgery). The main reasons for participation in the club are the desire to expand their knowledge in the specialty, acquire practical skills, to take part in research work. In addition, 95% of the surveyed postgraduate students were active participants in the SSCs according to the profile chosen in the specialty. The most attractive modes of work are clinical examinations, joint duty with the head of the SSCs in the clinic and participation in research work.

Conclusion. Active participation in SSCs provides an in-depth study of the area of interest in medicine and science, motivates students to continue research work upon graduation, admission to graduate school and develops a candidate’s pool of the teaching staff of the institution. The results revealed high demand among medical students for the experience of research work, the expansion and deepening of knowledge in the specialty, as well as the positive impact of participation in SSCs on the further formation of future clinicians.
Olympiad movement as a method of training high-level professional competencies
Authors: Prosyanik V. I. , Serebryakova O. V. , Serkin D. M. , Bogomolova I. K.
Published: April 2023

This paper shows the influence of students’ participation in the Olympiad movement in internal medicine on the development of their competencies. On the basis of the Department of Hospital Therapy and Endocrinology of the Chita State Medical Academy, an intra-university Olympiad in internal medicine was held for sixth-year students. We assessed the level of effectiveness of the competence-based approach as part of the active implementation of the Olympiad movement. This paper shows that participation in the Olympiad movement allows students to master a high level of competencies, form a clearer idea of the profession, which in the future makes it possible to prevent professional incompetence.
Semen Semenovich Zimnitsky’s contribution to the description of the clinic of infectious diseases, microbiology and immunology
Authors: Oslopov V. N. , Khazova E. V. , Khaliullina S. V. , Khasanov N. R. , Oslopova Yu. V. , Mishanina Yu. S. , Oslopova D. V.
Published: April 2023

The early period of S. S. Zimnitsky scientific activity is characterized by a passion for microbiology, immunology and infectious diseases. Of great importance was the three-year work abroad with I. I. Mechnikov and R. Virkhov. S. S. Zimnitsky gained worldwide fame for his discovery of Manchurian typhus. S. S. Zimnitsky investigated blood complements, proved the presence of "group immuniziny", treated croupous pneumonia with monovalent serum. An analysis of S. S. Zimnitsky works in the field of infectious diseases, microbiology and immunology, several biochemical studies indicate the great contribution of the scientist to the development of Russian biological science.
Continuity and orientation of the pedagogical process in a medical university
Authors: Skryabina Е/ N. , Nikitina Natalia M.
Published: April 2023

The article considers the problems of modern education and questions arising in a medical university, in particular: "What can be done to increase students’ motivation for the medical profession, increase its significance and reduce the outflow of postgraduates?"

The experience of the educational process in a internal medicine clinic aimed at improving the doctor-patient interaction is presented. The introduction of an additional course of psycho-pedagogical training aimed at developing the personal qualities, various forms of scientific work, expanding the possibilities of professional thinking, into the program of postgraduate education will contribute to the formation of a competent specialist.
Communication skills of a local general practitioner in conducting preventive counseling (methodological aspect)
Authors: Astanina S. Yu. , Kalinina A. M. , Shepel R. N. , Derinova E. A. , Mikhailova N. A. , Drapkina O. M.
Published: April 2023

The article considers the problem of developing communicative competence of local general practitioners in preventive counseling. The study showed that the process of preventive counseling is an integration of medical diagnostic, preventive and psychologicalpedagogical activities of a local general practitioner.

The paper presents the content of the doctor’s communicative competence, which is the ability and readiness to inform the patient about the examination results, to clarify information taking into account the individual patient characteristics, as well as to improve the patient’s medical adherence.

The indicators of achieving the anticipated results, expressed in communicative competence development, are determined, represented by communicative skills, which make up 3/4 of the total number of skills being formed, and the doctor’s skills in medical diagnostic and preventive activities, which make up 1/4 of the total number of necessary skills.

The results obtained made it possible to predict the most effective methods of preparing doctors for a brief preventive consultation and to determine the requirements for control and evaluation materials that provide an objective assessment of the development of identified skills. The obtained materials can serve as a basis for developing a methodology for developing doctor’s communicative skills in conducting preventive counseling and further quality monitoring.
Antidepressants and memory effects of ketamine under the neuromolecular view: A literature review
Authors: Da Silva GP Felipe , Rezende M Gabriel , Lohana Pompelli Scapatici , Luísa Zanelatto de Araujo , Bruna Carrara Lombardi , Caroline Vidal , David Batista Wiedmer , Lucas Schoeler , Minhoto R Gisele , Andreatini Roberto
Published: April 2023

Objective: Major Depressive Disorder (MDD) has as diagnostics characteristics chronic deep sadness, anhedonia, sleeping disorder, lower energy, and cognition impairment like memory deficits. Among the pharmacological treatments that have been used until the moment, most of them act by monoaminergic pathways. Overall, the antidepressant effects promoted by this kind of medication usually delay starting, resulting in treatment resistance by the patients; moreover, in some cases, this kind of treatment has shown to be inefficient in depression remission. With this, new treatments have been studied for resistant cases and an immediate antidepressant effect, for example, ketamine – whose action occurs in glutamatergic pathways. This study aimed to analyze, from a literature review, the molecular mechanisms involved in the action of ketamine - focusing on the neuroplastic hypothesis of depression. Methods: A literature search was conducted in PubMed, MEDLINE, and SciELO databases using the following terms as descriptors: "ketamine AND depression AND neuroplasticity," with criterion PICO, resulting in 60 bibliographic texts. Results/discussion: The studies analyzed demonstrated that ketamine could exert its antidepressant effects through the inhibition of GABAergic interneurons, activation of TRK-B/AKT/mTORC pathways involved with cell survival/growth through the neurotrophine BDNF and increased activation of AMPAr by glutamate. Furthermore, it is evident that the pharmacodynamics of ketamine involves different molecular cascades present in the impaired neural plasticity pathways in individuals with MDD. Conclusion: Thus, more research on the effectiveness of ketamine is needed to consolidate its use in MDD and to evolve with glutamatergic pharmacological therapy for other mental disorders, such as bipolar and neurodegenerative affective disorders, an example of Alzheimer's disease.
Karışık boyalı atıksuların paslanmaz çelik ve grafit elektrotlar kullanarak peroksi-koagülasyon yöntemiyle arıtılması
Authors: GÜMÜŞ Dilek
Published: April 2023

Boyalı atıksuların çoğu canlılar için toksik ve kanserojendir. Karmaşık yapılarından dolayı geleneksel arıtma yöntemleriyle arıtılmaları oldukça güçtür. Boyalı atıksuları arıtmak için çeşitli elektrokimyasal yöntemler geliştirilmiştir. Bu çalışmada karışık boyaların oluşturduğu sentetik atıksudan renk ve KOİ giderimi peroksi-koagülasyon yöntemi kullanılarak incelenmiştir. Anot ve katot olarak sırasıyla paslanmaz çelik ve grafit elektrotlar kullanılmıştır. Başlangıç pH, akım yoğunluğu ve elektroliz süresi gibi temel işletme parametrelerinin etkisi incelenmiştir. Parametrelerin elektrokimyasal sistem üzerindeki etkilerini incelemek için Taguchi deneysel tasarım yöntemi (L9) orthogonal array (OA) uygulandı. Sistemin performansı, Sinyal/gürültü (S/N) oranı (ne kadar büyükse o kadar iyidir) ve varyans analizi (ANOVA), faktörlerin yanıt değeri üzerindeki etkisinin göreceli olarak büyüklüğünü karşılaştırmak için değerlendirildi. Optimum çalışma koşulları başlangıç pH’ı 3, akım 100 mA ve reaksiyon süresi 60 dakika olarak bulundu. Bu koşullarda %99’un üzerinde renk giderimi ve %95 KOİ giderimi elde edilmiş ve toplam enerji tüketimi yaklaşık 25 kWh/kgKOİ olarak hesaplanmıştır.
BRAVE NEW WORDS
Authors:   Research and Educational Center of Foreign Languages, National Academy of Sciences of Ukraine, Ilchenko Olga
Published: April 2023

[Kramar N.A. A Dictionary of 21th Century English Neologisms. – Кyiv: Interservice, 2022. – 240 p.]
Activity of matrix metalloproteinase type 9 and its relationship with calcification of the thoracic aorta in patients with resistant hypertension: cross-sectional comparative study
Authors: Litvinova Marina  S. , Khaisheva Larisa A. , Shlyk Sergey V. , Aboyan Igor A.
Published: April 2023

Background. The extracellular matrix of vessels is degraded under the influence of matrix metalloproteinases (MMPs). MMP type 9 is of particular interest in arterial hypertension (AH) since its activity is regulated by a tissue inhibitor of matrix metalloproteinase type 1 (TIMP1). The balance of their ratio can shift in either direction depending on the disease stage and provoke vascular wall calcification.
Objective. This cross-sectional comparative study investigated the level of MMP9 and its type 1 tissue inhibitor and their relationship with the severity of thoracic aorta calcification in patients with resistant hypertension, depending on antihypertensive therapy effectiveness.
Material and methods. The study included 92 patients with resistant hypertension. All patients underwent 24-hour blood (BP) pressure monitoring (ABPM), and had their index of the thoracic aorta (ТАС) and the plasma levels of MMP9 and TIMP1 assessed.
Results. Patients were divided into groups based on whether they achieved the BP target level according to the results of ABPM: controlled (n=44) and uncontrolled (n=48) resistant AH. In the second group, most estimated parameters of ABPM were higher, and the variants of the daily BP profile for non-dipper and night-peaker systolic blood pressure (SBP) were more common than in the first group. In the second group, a more pronounced increase in TAC, TIMP1, and TIMP1/MMP9 levels was revealed. Evaluation of the relationship between the studied parameters revealed a positive relationship between TAC and age (r=0.683, p 0.00001), hypertension duration (r=0.610, p 0.00001) and a negative relationship with regular antihypertensive therapy duration (r=0.822, p 0.00001). ТАC was higher in individuals with higher values of SBP (r=0.513, р 0.00001), pulse BP (r=0.805, р 0.00001), rate of morning rise in BP (r=0.678, р 0.00001) and insufficient decrease in SBP at night (r=-0.822, р 0.00001). There was a positive correlation of moderate strength TAC with the level of low-density lipoproteins (r=0.490, p=0.0002), TIMP1 (r=0.344, p=0.005) and the TIMP1/MMP9 ratio (r=0.481, p 0.00001).
Conclusion. In patients with resistant hypertension, an increase in the TAC was revealed, which has a statistically significant direct correlation with the value of pulse BP, the morning rise in BP, and an insufficient decrease in SBP at night. An imbalance in the TIMP1/MMP9 ratio, rather than an isolated increase in MMP9, can indicate the intensity of the formation and degradation of the extracellular matrix components in patients with resistant AH, which triggers the vascular wall calcification process.
Analysis of factors influencing the values of parameters of intraoperative flowmetry of coronary bypass grafts: retrospective single-center cross-sectional study
Authors: Bazylev Vladlen V. , Tungusov Dmitry S. , Senzhapov Ilgiz Ya. , Garanyan David N. , Mikulyаk Artur I.
Published: April 2023

Оbjective. This study determines the factors that can affect the value of the parameters of intraoperative flowmetry of coronary bypass grafts.
Material and methods. TTFM is a routine procedure accompanying coronary artery bypass grafting at the Federal State Budgetary Institution FTSSSh (Penza). This retrospective study included 995 consecutive patients who underwent isolated coronary artery bypass grafting of the left coronary artery. The exclusion criteria were damage to the right coronary artery bed, the emergency nature of the operation, and the combined pathology of the valvular apparatus. Patients who underwent anastomosis revision due to flowmetry parameters changes were also excluded from the study. Intraoperative assessment of coronary artery bypass grafts was performed using VeryQ and MiraQ MediStim flowmeters (Norway).
Results. A total of 1733 arterial and 479 venous grafts were evaluated. The following factors influenced the average volumetric blood flow velocity value: composite shunting of the border stenosis increases the chance of reducing the volumetric blood flow below the threshold value by 1.841 times (OR=1.841; p=0.018), the combination of occlusion and borderline stenosis with composite shunting increases the chance of reducing the volumetric blood flow velocity by 3.91 times (OR=3.91; p=0.041), an increase in the diameter of the bypassed artery by 1.0 mm reduces the chance of a decrease in blood flow volume velocity by 53.7% (OR=0.423; p=0.05).
Conclusion. The following factors influence the peripheral resistance index: coronary artery diameter (OR=0.21; p=0.001), degree of artery proximal stenosis (OR=0.987; p=0.034), the vascular wall condition (OR=2.25; p=0.05), type of conduit used (OR=0.298; p=0.002), and shunting method (OR=1.699; p=0.017). The following factors influence the mean volumetric blood flow velocity value: bypass method (OR=1.841; p=0.018), a combination of occlusion and borderline stenosis in composite bypass grafting (OR=3.91; p=0.041), and the bypassed artery diameter (OR=0.423; p=0.423; p=0.05).
Modern possibilities of intensive treatment of dyslipidemia and gaps in its control: literature review
Authors: Larina Vera N. , Golovko Milada G. , Larin Vladimir G. , Mironovna Tatyana N. , Orlov Denis A.
Published: April 2023

The article discusses modern approaches to screening for dyslipidemia and its control, target levels of low-density lipoproteins (LDL), initiation of lipid-lowering therapy depending on the total risk on the Systematic Coronary Risk Evaluation (SCORE) scale, considering the effects of age, gender, smoking, blood pressure, lipid levels, which are of crucial importance for selecting preventive and therapeutic strategies in patients with several risk factors. Different types of therapy for dyslipidemia are discussed as of monotherapy with statins and, in combination with ezetimibe, inhibitors of the enzyme proprotein convertase subtilisin-kexin type 9 (PCSK9). New lipid-lowering drugs are highlighted: bempedoic acid and inclisiran, a synthetic small interfering RNA (siRNA) conjugated with a hydrocarbon of three-antennary N-acetylgalactosamine, which activates the natural RNA interference mechanism to cleave the mRNA of the PCSK9 enzyme and prevent its translation into a protein molecule. This increases the number of receptors for LDL and reducing their amount in the blood. We present our results of assessing the use of lipid-lowering therapy and achievement of the target LDL value in very high-risk patients. Innovative biotechnological drugs based on human monoclonal antibodies or antisense oligonucleodins create additional opportunities for improving the treatment of statin-resistant forms of dyslipidemia in patients with a very high cardiovascular risk. The article aims to increase the level of knowledge about modern approaches to lipid-lowering therapy of general practitioners, cardiologists of the primary care settings and will be of interest to other specialists.
Reduction in global tissue deformation of the left ventricle as a cause of heart failure and worse quality of life in patients with takotsubo syndrome in the long period of the disease: prospective cohort study
Authors: Evdokimov Dmitry S. , Boldueva Svetlana A. , Feoktistova Valeria S.
Published: April 2023

Objective. This study evaluates the severity of chronic heart failure (CHF), ejection fraction (EF), and global contractility of the left ventricle (LV) using Speckletracking (STE) in patients with takotsubo syndrome (TS) in the early and late disease stages of the disease and compares these data with an assessment of the quality of life (QoL) of patients.
Material and methods. The study included 60 patients with TS, with a mean age of 65.513.4 years. The severity of CHF symptoms was assessed using the SHOKS scale (assessment of the clinical condition in CHF). The Minnesota Questionnaire and the HeartQol questionnaire were used to study QoL. Echocardiography data (ECHOCG) were recorded during the acute period and at discharge from the hospital. In the late disease period, ECHOCG was performed using the STE method. After 1 year, endothelial function was studied using the EndoPAT 2000 device to determine the reactive hyperemia index.
Results. According to the SHOKS scale, the severity of CHF symptoms corresponded to 12 functional class (FC) in all patients with TS in the long-term disease; however, before the development of TS, only 15 people had signs of CHF at the level of 12 FC. According to ECHOCG, LVEF in patients with TS was 44.59.7% at admission, 60.27.6% at discharge, 61.69.2% after a year, and 60.09.0% after 2 years. The average values of global longitudinal and global circular deformation of the left ventricle in patients with TS were 14.03.1 and 15.04.1%, respectively, after 1 year from disease onset and 12.31.9 and 13.11.9%, respectively, after 2 years. When comparing the data of the Minnesota Questionnaire and HeartQol questionnaires, QoL in the long-term of ST was significantly lower than the initial one before disease development. Mean reactive hyperemia index values after 1 year were 1.740.19.
Conclusion. Despite the complete restoration of LVEF in patients with TS, clinical manifestations of CHF persist. Using the STE technique during the long term, 90% of patients had abnormalities in the global tissue deformity of the left ventricle. These changes may explain the CHF clinical manifestations and QoL decrease in patients with TS during long-term disease.
Influence of prosthesis – patient mismatch on long-term results in patients after aortic valve replacement with a biological prosthesis: retrospective single center study
Authors: Bazylev Vladlen V. , Tungusov Dmitriy S. , Babukov Ruslan M. , Bartosh Fedor L. , Mikulyak Artur I. , Levina Alena V.
Published: April 2023

Background. Despite numerous studies, ambiguity remains at present regarding the impact of prosthesis-patient mismatch (PPM) on long-term outcomes after aortic valve (AV) replacement.
Objective. This study evaluates the effect of PPM on long-term results in patients after AV replacement with a biological prosthesis.
Material and methods. We retrospectively analyzed the data of 231 patients who underwent AV replacement with a biological prosthesis from 2010 to 2018 at the Penza Federal Center of Cardiovascular Surgery. Patients were implanted with the following biological prostheses: Medtronic Mosaic, Edwards PERIMOUNT, Biocor.
Results. Moderate PPM was present in 131 patients (56%), and severe PPM in 1 patient (0.7%). The mean follow-up was 78.832 months. There were no significant differences in hospital mortality in patients with and without PPM, 4 (3%) and 3 (2,9%), respectively, p=0.9. In the long-term period, patients with PPM showed a slower regression of left ventricle (LV) mass and recovery of LV contractile function than patients without PPM, p=0.05. There was no significant difference in survival in the long-term follow-up period between patients with and without PPM long-term survival, 77.7% and 79%, respectively, p=0.6. Also, there were no significant differences in major adverse cardiac events and the freedom from adverse events was 90% and 91%; p=0.7. However, there was a tendency to more frequent hospitalization for chronic heart failure (CHF) exacerbation in the patient group with PPM than in those without PPM, 63.8% and 78%; HR 1.6; 95% CI 0.932.1, p=0.007. There was also a tendency for an increased biological valve structural degeneration in the group with PPM than in the group without PPM 76% and 87%, HR 1.4; 95% CI 1.43.1, p=0.01 According to the Cox regression, the overall postoperative mortality predictors were diabetes mellitus, vascular atherosclerosis HR 5; 95% CI 1.222, p=0.04 and HR 2.9; 95% CI 1.46.6, p=0.01 respectively. Predictors of the risk of hospitalization due to CHF exacerbation were previous myocardial infarction and PPM HR 0.4; 95% CI 0.20.9, p=0.04 and HR 1,5; 95% CI 0.92; p=0.005, respectively PPM HR 2; 95% CI 0.854.1, p=0.01.
Conclusion. PPM is a common complication after AV replacement with a biological prosthesis. It is associated with a slower regression of LV mass, an increased risk of structural valve degeneration, and hospitalizations for exacerbated heart failure.
Kontribusi Beban Akademik dan Manajemen Waktu Terhadap Kejenuhan Akademik Pada Peserta Didik SMKN 6 Malang
Authors: Zahroh Anisa Hayatuz , Rahman Diniy Hidayatur , Santoso Djoko Budi
Published: April 2023

Abstract: Academic load and time management are factors that can contribute to student burnout. In this study, it was found that students of SMKN 6 Malang who experienced burnout were in high category is 19 percent, and those who were experiencing burnout in medium category is 62 percent, while in the low category by 19 percent. The purpose of this research was to determine the contribution of academic load and time management in students' academic burnout at SMKN 6 Malang. This study uses a correlational design with a subject of 310 students of SMKN 6 Malang. Data collected with  the academic load inventory instrument, time management inventory instrument and academic burnout inventory instrument. Data was analyze with simple linear regression tests using the IBM SPSS Statistic 16 For Windows application. The results showed, the significance value of academic load against academik burnout  was 0.00 which means there was a contribution between academic load on academic burnout, the significance value of the time management against academic burnot was 0.135, which means there was no contribution between time management and academic burnout.

Abstrak: Beban akademik dan manajemen waktu merupakan faktor yang dapat mengakibatkan timbulnya kejenuhan pada peserta didik. Dalam penelitian ini diketahui peserta didik SMKN 6 Malang yang mengalami kejenuhan dengan kategori tinggi sebesar 19 persen, dan yang mengalami kejenuhan dengan kategori sedang sebesar 62 persen, sedangkan dengan kategori rendah sebesar 19 persen. Penelitian ini bertujuan untuk mengetahui kontribusi beban akademik dan manajemen waktu terhadap kejenuhan akademik peserta didik SMKN 6 Malang. Penelitian ini menggunakan desain korelasional dengan subjek sebanyak 310 peserta didik SMKN 6 Malang. Pengumpulan data menggunakan instrumen inventori beban akademik, instrumen inventori manajemen waktu dan instrumen inventori kejenuhan akademik. Data dianalisis dengan uji regresi linier sederhana menggunakan bantuan aplikasi IBM SPSS Statistic 16 For Windows. Hasil penelitian menunjukkan bahwa nilai signifikansi beban akademik terhadap kejenuhan akademik bernilai 0,00 yang berarti terdapat kontribusi beban akademik terhadap kejenuhan akademik, dan nilai signifikansi manajemen waku terhadap kejenuhan akademik bernilai 0,135 yang berarti tidak terdapat kontribusi manajemen waktu terhadap kejenuhan akademik.
Dukungan Orang Tua, Ekspektasi Karier dan Hubungannya dengan Motivasi Belajar Siswa di SMK Negeri 5 Malang
Authors: Rohmawati Laili Indah Sari , Indreswari Henny , Flurentin Elia
Published: April 2023

Abstract: This research examines the problems of lack of learning motivation experienced by students of SMK Negeri 5 Malang, as well as factors related to these problems. The purpose of this study is to determine the correlation between student learning motivation problems and parental support obtained by students and student expectations for future careers. This is important to research as a basis for providing services to increase student learning motivation. The type of research used is correlational descriptive research. The population in this study was class XI and XII at SMK Negeri 5 Malang. Sampling was performed using a Cluster Random Area. The data retrieval technique uses questionnaires and the data is analyzed using multiple linear analysis. The results of this study show that; (1) there is a correlation between parental support and student learning motivation; (2) there is a correlation between career expectations and learning motivation; (3) there is a correlation between parental support, career expectations and learning motivation. Results of this research can be used to provide services that can improve the provision of support from parents to students and also services that can increase students' expectations of future career. It is hoped that these services can increase student learning motivation.

Abstrak: Penelitian ini mengkaji mengenai problematika kurangnya motivasi belajar yang dialami oleh siswa SMK Negeri 5 Malang, dan variabel lain yang berhubungan dengan permasalahan tersebut. Penelitian ini bertujuan untuk mengetahui gambaran korelasi antara dukungan orang tua dan ekspektasi karier dengan motivasi belajar siswa.  Hal tersebut penting diteliti sebagai dasar pemberian layanan untuk meningkatkan motivasi belajar siswa. Jenis penelitian yang digunakan adalah penelitian deskriptif korelasional. Populasi pada penelitian ini adalah kelas XI dan XII di SMK Negeri 5 Malang. Pengambilan sampel dilakukan dengan menggunakan Cluster Random Area. Teknik pengambilan data menggunakan kuesioner dan data dianalisis menggunakan analisis linier berganda. Hasil penelitian ini menunjukan bahwa; (1) terdapat hubungan antara dukungan orang tua siswa dengan motivasi belajar siswa; (2) terdapat hubungan antara ekspektasi karier dengan motivasi belajar; (3) terdapat hubungan antara dukungan orang tua, ekspektasi karier dengan motivasi belajar. Hasil dari penelitian ini, dapat digunakan sebagai acuan dalam membuat program layanan bimbingan dan konseling. Diharapkan dari pemberian layanan tersebut, dapat meningkatkan dukungan orang tua, ekspektasi karier serta motivasi belajar siswa.
Pengembangan Panduan Teknik Self-Management Berbantuan Google Calender untuk Menurunkan Prokrastinasi Akademik Siswa SMP
Authors: Isnainingtyas Zahwa , Muslihati Muslihati , Prihatiningsih Riskiyana
Published: April 2023

Abstract: Procrastination is activity carried out to delay students' school assignments given by the teacher. One form of procrastination that is often found in students is delay in submitting assignments. Solving procrastination problems can use various guidance and counseling services. Self-management is an effort to make student study schedules work well. This study aims to produce a Google Calendar-assisted self-management guidebook to reduce academic procrastination in junior high school students. The method used is research and development (R and D) adapted from the Bord and Gall development model. Data analysis in this study used quantitative data analysis and descriptive data. The subjects of this study were two material experts, two media experts, and two prospective users. The results showed that the product developed was included in the very precise classification obtained from the assessment of the material expert test questionnaire with a score of 0.94, the questionnaire assessment from the media expert test with a score of 1, and the results of the prospective user test assessment with a score of 1. These results can be used as counselors in helping students to reduce student academic procrastination at SMP Negeri 21 Malang.

Abstrak: Prokrastinasi merupakan suatu kegiatan yang dilakukan untuk menanguhkan tugas sekolah siswa yang diberikan oleh pendidik. Salah satu bentuk dari prokrastinasi yang sering dijumpai pada siswa adalah keterlambatan dalam mengumpulkan tugas. Penyelesaian permasalahan prokrastinasi dapat menggunakan berbagai layanan bimbingan dan konseling. Self management salah satu upaya untuk membuat jadwal belajar siswa dapat terlaksana dengan baik. Penelitian ini bertujuan menghasilkan buku panduan self-management berbantuan Google Calendar untuk menurunkan prokrastinasi akademik siswa SMP. Metode yang digunakan yakni penelitian dan pengembangan (R dan D) yang diadaptasi dari model pengembangan Bord dan Gall. Analisis data peda penelitian ini menggunakan analisis data kuantitatif dan data deskriptif. Subjek penelitian ini ialah dua ahli materi, dua ahli media, dan dua calon pengguna. Hasil penelitian menunjukkan bahwa produk yang dikembangkan masuk dalam klasifikasi sangat tepat yang didapat dari penilaian angket uji ahli materi dengan skor 0, 94, penilaian angket dari uji ahli media dengan skor 1, dan hasil penilaian uji calon pengguna dengan skor 1. Hasil tersebut dapat dijadikan konselor dalam membantu siswa untuk menurunkan prokrastinasi akademik siswa di SMP Negeri 21 Malang.
Leveraging on Machine Moderation to Improve Content Organization
Authors: Fadziso Takudzwa
Published: April 2023

The growing pressure from the government on operators of different platforms on the needs to manage content in order to eliminate misinformation and ‘hate speech, this study examines the introduction of machine moderation mechanisms; surveys approximately the prevailing automated tools employed by key players in social media to manage rights violation, sabotage and hate speech; and recognizes major structures as the requirement for the implementation. We attempt to address the purpose of this paper by reviewing some selected pieces of literature. The article provides automated ‘hash matching and projecting artificial intelligence or machine learning devices. We also define machine moderation as a technological approach set up to demeanor content moderation at balance by foremost platforms for user-created content like YouTube, Facebook, and Twitter.
Why Neuralink will Change Humanity Forever?
Authors: Fadziso Takudzwa
Published: April 2023

We go over new and current creations that use Artificial Intelligence to enable our use of the devices as the days fly by. This unforeseen flood in the use of AI has increased fragility among individuals that it can leave us without any use. This increased vulnerability prompted people to work out what could be possible between robotics and man-made logic to keep our future secure. The deal also came out, combining all perspectives and achieving a positive relationship between humans and AI. We should use the "Neural Lace" innovation as well as the Brain-Machine Interface (BMI) to do this. The paper explored the use of the Brain-Machine Interface, Artificial Intelligence, and Neural Network in order to achieve beneficial contact with AI alongside the entity that makes this conceivable, Neuralink, an Elon Musk startup that has a dream to repair the vulnerability among us.
The Comparison of The United States Foreign Policy Against The Islamic World Under President Barack Obama and President Donald Trump Administration
Authors: Bahari Diana Mutiara , Sahide Ahmad
Published: April 2023

The United States of America (USA) is an international concern, especially regarding the national election agenda. The presidential election of the world's leading superpower will impact the world's geopolitical order, such as the emergence of global political turmoil that has resulted in tensions in relations between the US and countries in the world, especially countries in the Islamic World. The 2016 US presidential election has captured international attention because it was won by a controversial figure, Donald Trump. The victory of Donald Trump to replace President Barack Obama marked a change in the style of US foreign policy towards the Islamic World. Therefore, the question arises of how the US foreign policy compares to the Islamic World in the era of President Obama and President Trump. This study uses a Foreign Policy Decision Making Theory. This study concludes that US foreign policy during the Obama administration was friendly to the Islamic World. On the other hand, US foreign policy during the Trump administration was not friendly to the Islamic World, which caused tension in relations between the US and the Islamic World.Keywords: US, Barack Obama, Donald Trump, Islamic World, Foreign Policy
Trump’s Securitization of US against Aliens and Immigrants Case Study: Latin Migrants
Authors: Sitompul Eiga , Cipto Bambang
Published: April 2023

This paper examines Trump’s securitization of Latin migrants and aliens in the United States (US) through law enforcement and legal political practice. Public citizens have divided opinion regarding immigrants, especially aliens, as they are undocumented and are deemed to destabilize internal public safety. Politicians in the US have also conduct political competitions in politicizing migrants through multitudes of official matters, and passing policies. One prominent example in politicizing migrant is Donald J. Trump, a popular unorthodox president of the US that views immigrants with hostility and skepticism. Trump antagonized the Latin migrants through the dangers they posed in the past combined with crime occurrences in his term, and justify protectionist policies by reducing border crosses through Mexico-US border and cutting down the number of Latin aliens and immigration in the country. Trump, through his famous Zero-tolerance policy, promoted attitudes that often encourage public citizens and law enforcers to view potential threats of immigrants, especially aliens. Trump’s campaign about Latin migrants changed the image of Latin migrants among Trump supporters as well as local law enforcers in viewing Latin migrants as a source of threat. This research finds that: Trump’s securitization of US against Latino migrants was lawfully and effectively projected through empowerment of federal level immigration and law enforcement agencies down to field officers.
THE ROLE OF PARADIPLOMACY AND THE POTENTIAL PROTO-DIPLOMACY IN THE UNITARY STATE
Authors: Fathun Laode Muhamad
Published: April 2023

This article aims to explain the study of paradiplomacy in the unitary state. With the case study of Indonesia, the author explains the role of paradiplomacy and the potential of proto-diplomacy in a unitary state like Indonesia. This article uses a qualitative method with a case study method with research data sources, journal articles, books, reports and other relevant sources. The results found that the role of paradiplomacy in Indonesia is still conservative because it still follows the boundaries that have been set. Post-reform the role of paradiplomacy is very stretched, especially in big cities such as Jakarta, Bandung, Surabaya, which already have strategic partners abroad. This role opens up opportunities for cooperation in economic, social, cultural, educational and other fields that are needed by para-diplomacy. The role of paradiplomacy has been stated in various regulations as the basic foundation for moving in search of strategic partners abroad. Although it has a positive impact, it turns out that there is potential for proto-diplomacy in Indonesia. This is especially the case for areas that have a history of popular movement for regional independence. This movement has the potential to lead to disintegration. However, it can be muted if each party can reduce ego and commitment to build together.
Propaganda and Political Memes on Social Media in the 2019 Indonesian Presidential Election
Authors: Aminulloh Akhirul , Qorib Fathul , Fianto Latif , Setiamandani Emei Dwinanarhati
Published: April 2023

Political memes colored the 2019 Indonesian presidential election campaign on social media. Political memes have become one of the propaganda strategies to influence public opinion to gain political support from the public before the presidential election. This study aims to analyze and understand political memes as a medium of political propaganda in the 2019 Indonesian presidential election. This study uses critical discourse analysis to uncover the meaning behind the text. The data collection technique uses documentation in the form of political memes of the two presidential candidates, both in images and political symbols scattered on social media in the January – March 2019 period. Furthermore, the data will be analyzed using Fairclough's critical discourse analysis model to find out the meaning of the text. This study indicates that social media plays an essential role in political communication in the 2019 presidential election campaign. Social media is a cheap and fast means of spreading political memes that reach potential voters widely and massively. Through political memes, Joko Widodo often talks about having links with the Indonesian Communist Party. Meanwhile, Prabowo Subianto is often spoken of by his political opponents as a supporter of the caliphate in Indonesia. These political memes are used as political propaganda to construct or deconstruct political presidential candidates' discourse and build or damage the reputation of presidential candidates to influence public opinion.
Turkey’s Reasons to Normalize Diplomatic Relations with Israel in 2021
Authors: Mufidah Isyfa Zahrotul , Prasodjo Haryo , Rijal Najamuddin Khairur , Prakoso Havidz Ageng
Published: April 2023

This article discusses the reasons for Turkey's normalization with Israel in 2021. Diplomatic relations between the two sides have been established for more than 70 years since the state of Israel was founded, although the dynamics of their relationship have experienced ups and downs. This study is qualitative research in which the analysis of this phenomenon is taken from news reference sources, articles, reports and documents, using the theory of Foreign Policy Analysis by Valerie M.Hudson. The results of this analysis show that three important aspects make Turkey carry out normalization with Israel, first from an economic perspective which is the main aspect of normalization, second from a political aspect and finally from a security or military perspective. Israel has become Turkey's strategic partner even though as an Islamic country that carries out normalization with the Jewish state, this is a strategy that Turkey wants to build, because this policy it is the foundation for achieving national interests.
Japan’s Strategy on Managing Territorial Disputes of Senkaku Islands
Authors: Dirha Kirana Essa Rahmadhani , Pratama Irsadanar Rafyoga Jehan
Published: April 2023

The purpose of this study is to clarify and provide new information regarding the Japanese approach to handling territorial issues involving the Senkaku Islands. By applying the Negotiation and Mediation theory by Dean G. Pruitt and Peter J. Carnevale to evaluate and further explain the types of negotiations between Japan and China to resolve the territorial issues of the Senkaku Islands, it will explain the process of Japan's strategy for doing so. The study discovered that both countries went through several dynamics in their negotiating process using the Negotiation and Mediation theory. To identify the best way to develop a solution, Japan and China used two strategies: the first was the contesting strategy, which took place at the start of the negotiating process, and the second was the yielding or concession strategy. Finally, carry out the problem-solving plan whereby both parties agreed to host a Joint Development to put an end to the territorial disputes over the Senkaku Islands.
Islamophobia and Misconception : A Systematic Literature Review
Authors: Tristantri Cepi Novia , Zahidi M Syaprin , Salahudin Salahudin
Published: April 2023

This research aims to determine the development of the phenomenon of Islamophobia and misconceptions about Islam and Muslims that occur in the world. The research method used is a systematic literature review (SLR) using 580 scientific journal articles from the Scopus database. The article analysis uses RIS Scopus data which is visualized using the Vos Viewer application to determine the co-occurrence of the article data obtained. From the analysis carried out, the results reveal that the study of Islamophobia and Misconceptions has long been a concern of scholars/researchers. This is evidenced by the many relevant topics and sub-themes that exist. This study also concludes that the phenomenon of tidal Islamophobia is following the dynamics of events that occur. The results of this research contribute to describing the magnitude of Islamophobia against Islam and Muslims in the world. This research also contributes as a reminder to the world of the importance of maintaining peace and tolerance. The drawback of this research is that the articles used as authorship references are only sourced from the Scopus database. So that the results presented in this scientific article are not able to fully describe Islamophobia and its misconceptions that occur in the world. From this lack of scientific article writing, it is hoped that further research can use scientific articles sourced from databases of other accredited international journals, such as Web of Science (WoS), Thomson Reuters, Elsevier, and Springer.
Correlation of mitotic activity and Ki 67 with BR score and molecular classification in carcinoma breast
Authors: Satyajit Singh Gill  , Nutan Jumle  , Aleena Babu  , Saumya Lal  , Ritu Sharma  , Rohit Singh Rajput  , Dnyanesh Limaye
Published: April 2023

Background: To determine if mitotic activity played a role in classifying breast cancer in terms of its biological behaviour. We investigated the prospect of identifying a more meaningful cell proliferation marker for categorising treatment-naive breast cancer.
Methods: The 150 cases diagnosed as invasive breast carcinoma in the histopathology section were systematically studied for the clinical, gross, and microscopic features.
Results: the 50% patients were grade 2 (75), 41% were grade 3 (71) and 9% (14) were grade 1 in present study. The distribution of intrinsic subtypes was luminal A 25% (38), luminal B 59% (88), HER2 enriched 10% (15), basal 6% (9). Out of 150 cases, 29% (43) cases were T1, T2 were 65% (97), T3 were 2% (4), T4 were 4% (6). Mean Ki 67 was 15.6±8.8 in grade 1, 23.3±15.4 and 38.2± in grade 3. There was significant difference between I and III, and II and III (p<0.05). Mean mitotic count in grade 1 was 5.4±2.7, in grade 2 it was 9.7±13.5, in grade 3 it was 16.1±6.9. There was significant difference between grade 1 and 2, grade 2 and 3, grade 1 and 3 (p<0.05). There was significant difference between T stages (p<0.05).
Conclusions: Ki 67 showed a more significant statistical correlation with prognostic factors as compared to mitotic count; we feel Ki 67 is more superior to mitotic count as a prognostic factor.
Frequency of nodal metastasis in differentiated thyroid carcinoma
Authors: M. Abdullah Al Mamun  , Muhammad Ariful Islam  , M. Hasibur Rahman  , M. Saiful Islam  , Mahmud Asif Rifat
Published: April 2023

Background: Thyroid cancer is the most common endocrine malignancy. Moreover, within thyroid cancer, differentiated thyroid carcinoma (DTC) is the most common variety, with the incidence rising over the past decade. Often, most of the cases present with multicentric disease and presenting with lymph node metastases at the time of diagnosis. Nodal metastasis has prognostic importance, and it may guide surgeons regarding further management. Considering this scientific fact, the study was performed to see the frequency of lymph node metastasis in DTC among the patients admitted to a tertiary care hospital.
Methods: This cross-sectional study was conducted in the department of otolaryngology and head-neck surgery, Sher-E-Bangla Medical College Hospital, for 9 months after the acceptance of the protocol. A total of 50 patients (in all age groups) who attended the relevant department due to thyroid malignancies were approached and interviewed. Thorough history taking, physical examination, and relevant investigation were done and recorded into separate case record forms. Informed written consent was taken from each subject. Following collection, data were coded and inputted into statistical software. Data analysis was done with SPSS 21 according to the objective of the study. Data were presented in the form of tables, and charts.
Results: Among the 50 patients, the mean age of the patients was 47.86±15.69 SD (years) with minimum and maximum ages of 14 and 78 years respectively. The male-female ratio was 1:4 (20% male vs 80% female). Papillary carcinoma was the most frequent (88%) followed by follicular (10%). Nodal metastasis was most common in the papillary variety, about 54.55% of cases, whereas 20% were present in the follicular variety. The majority of the patients underwent total thyroidectomy with neck dissection (90%) and the remaining cases were managed by lobectomy (10%).
Conclusions: This study concluded that nodal metastasis was present in 54.55% of cases of papillary carcinoma.