bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and Sonological Evaluation of Borderline Amniotic Fluid Index and Oligohydramnios-Its Correlation with Perinatal Outcomes
Authors: Jamsheed Saira , Abid Khadijah
Published: January 2024

Objective: To evaluate the correlation of low borderline amniotic fluid index and oligohydramnios with perinatal outcomes among pregnant females presenting at the tertiary care hospital of Karachi. Study Design: Cross-sectional study.Place and Duration of Study: The study was conducted at the Department of Obstetrics and Gynecology, Hamdard University, Karachi, Pakistan, from March 2021 to March 2022.Methods: Females aged 18-45 years, with a gestational age of 20-42 weeks assessed on the last menstrual period and a single fetus on ultrasound were enrolled. The final sample size for the study was determined to be 260 with 130 participants in each group, i.e., the females with Amniotic Fluid Value (AFI) value of ≤5 cm considered as oligohydramnios (group-1) and AFI value of 5.1 to 8 cm considered as borderline AFI (group-2)The amniotic fluid index value was determined in all the females using ultrasonographic reports by the consultant physicians. Females were classified as having oligohydramnios if their amniotic fluid index value was less than 5 cm and borderline amniotic fluid index between 5.1 and 8 cm. To evaluate the maternal and perinatal outcomes, all females were monitored up to birth. Data was analyzed using SPSS version 23.Results: The mean maternal age was 29.85±5.45 years, and the mean BMI was 29.78±5.62 kg/m . Most of the females had gravida ≥1. Females with oligohydramnios had higher rates of low birth weight (84.6% vs. 51.5%, p=0.001), IUGR (68.5% vs. 22.3%, p=0.001), meconium staining (42.3% vs 7.7%, p=0.001), low APGAR score (50.8% vs. 13.8%, p=0.001), respiratory distress syndrome (72.3% vs 27.7%, p=0.001), birth asphyxia (65.4% vs 23.1%, p=0.001), NICU admission (73.8% vs. 43.1%, p=0.001), and neonatal death (21.5% vs. 5.4%, p=0.001) than women with borderline amniotic fluid index.Conclusion: This observational study demonstrates a significant correlation between oligohydramnios and adverse perinatal outcomes, emphasizing the importance of vigilant monitoring and intervention in pregnancies with low amniotic fluid. How to cite this: Jamsheed S, Abid K. Clinical and Sonological Evaluation of Borderline Amniotic Fluid Index and Oligohydramnios-Its Correlation with Perinatal Outcomes. Life and Science. 2024; 5(1): 16-21. doi: http://doi.org/10.37185/LnS.1.1.378
Comparison of Early and Delayed Feeding after Elective Gut Anastomosis
Authors: Jabbar Ghazanfar , Ahmed Mirza Sijeel , Malik Arsalan Sharif , Akhtar Shahzad , Minhas Farooq Sultan , Makshoof Muhammad Talha , Shahid Zoha
Published: January 2024

Objective: To compare the effects of early and delayed feeding after elective gut anastomosis in relation to a mean number of days of audible bowel sounds.Study Design: A cross-sectional study.Place and Duration of Study: The study was conducted at the Department of Surgery, Combined Military th th Hospital (CMH), Rawalpindi, Pakistan, from 11th May 2019 to 10th November 2019.Methods: A total of 60 individuals undergoing gut anastomosis were divided into two groups. In group A, the NG tube was removed within 6 to 24 hours of surgery, and clear oral liquids (30ml/hour) were started. Oral fluids, including juices and soups on the other day after surgery, tailed by semisolid food at 3rd day, then regular food at 4 day and finally discharge at the 5 day. In group B, the NG tube was detached three to five days after the procedure, observing NG tube output <30-50cc daily. Then, patients were followed up in post-surgical wards for 48 hours. Patients were noted and informed of the time when bowel sounds were audible, the first flatus passed, and the first stool passed. Results: The mean age in group A was 40.23 ± 15.66 years, and in group B was 37.93 ± 15.23 years. Most of the patients, 31 (51.67%), were between 16 to 30 years of age. Out of 60 patients, 36 (60.0%) were males and 24 (40.0%) were females, with male to female ratio of 1.5:1. The mean number of days of audible bowel sounds in Group A (early feeding) was 1.57 ± 0.63 days while in Group B (delayed feeding) was 3.90 ± 0.76 days (p-value = 0.0001). Conclusion: This research established that the outcome of early feeding is better than the outcome of delayed feeding after elective gut anastomosis.

How to cite this: Jabbar G, Ahmed MS, Malik AS, Akhtar S, Minhas FS, Makshoof MT, Shahid Z. Comparison of Early and Delayed Feeding After Elective Gut Anastomosis. Life and Science. 2024; 5(1): 101-106. doi: http://doi.org/10.37185/LnS.1.1.411
Assessment of Diagnostic Accuracy of Digital Breast Tomosynthesis in Distinguishing Malignant and Benign Breast Lesions
Authors: Afzal Kanza , Gul Nadia , Mehmood Khalid , Jawwad Sobia , Iqbal Bushra
Published: January 2024

Objective: The study aims to determine the diagnostic accuracy of digital breast tomosynthesis in diagnosing malignant and benign lesions, keeping histopathology as the gold standard.Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the Department of Diagnostic Radiology, POF th th Hospital, Wah Cantt, Pakistan over a period of six months from 11th  July 2021 to 11th January 2022.Methods: A total of 200 women presenting with suspicion of breast malignancy were selected consecutively from the outpatient department, and Digital Breast Tomosynthesis(DBT) was performed, followed by a biopsy of the specimen to confirm the findings on histopathology. Results: The average age of the sample was 48.3 + 7.1 years, ranging between 35 and 60 years. Palpable breast lump was recorded in 44.5%, pain in 33%, and nipple discharge in 35.5%. Family history of breast Ca was present in 25.5. On Digital Breast Tomosynthesis (DBT), 58.5% of lesions were labeled as malignant, while 53.5% were labeled as malignant on follow-up histopathology. On applying the formulae for calculation, the sensitivity of DBT was found to be 86% and specificity 73.1%. The positive predictive value of the DBT is 78.6%, and the negative predictive value is 81.9%.Conclusion: In conclusion, Digital Breast Tomosynthesisis a significantly sensitive and specific tool for detecting malignant breast lesions in women suspected of breast carcinoma.How to cite this: Afzal K, Gul N, Mehmood K, Jawwad S, Iqbal B. Assessment of Diagnostic Accuracy of Digital Breast Tomosynthesis in Distinguishing Malignant and Benign Breast Lesions. Life and Science. 2024; 5(1): 3-8. doi: http://doi.org/10.37185/LnS.1.1.416
Assessment of Post-Traumatic Stress Disorder and Role of Spirituality Amongst Caregivers of Pediatric Cancer Patients in Pakistan
Authors: Bashir Noman , Ain Qurat ul , Karim Noor-E- , Niazi Hafsa , Khan Muhammad Ibrahim , Asghar Areej Khan
Published: January 2024

Objective: This study examined the levels of Post-Traumatic Stress Disorder (PTSD) in pediatric cancer caregivers and the impact of spirituality on PTSD in Pakistan. Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the Department of Oncology, Shaukat Khanum Memorial Cancer Hospital & Research Centre, Peshawar, Northwest General Hospital & Research Centre, Peshawar in Khyber Pakhtunkhwa (KPK), Pakistan Institute of Medical Sciences, Islamabad and Quaid-e-Azam International Hospital in Islamabad, Pakistan from January 2023 to March 2023.Methods: The study comprised 153 Caregivers of pediatric cancer patients aged One month –12 Years using convenience sampling. The PTSD Checklist-Civilian Version (PCL-C) and Caregiver's Spirituality Scale (CSS-10) were used to collect data. Results: Results of the study found that 81 caregivers (52.94%) had high PTSD, and 96 (62.74%) had high spirituality. Females reported higher PTSD and spirituality than guys. Graduates have more PTSD and spirituality than illiterates and matriculate. PTSD and spirituality had a negative Pearson's Correlation Coefficient. Conclusion: The study emphasizes spirituality as a caregiver's mental health protector. Healthcare practitioners caring for pediatric cancer patients can use the findings to lessen PTSD symptoms by targeting caregivers' spiritual needs. Convenience sampling and self-report measurements decrease generalizability. Future study is needed to investigate the association between PTSD and spirituality in caregivers of pediatric cancer patients.How to cite this: Bashir N, Ain Q, Karim N, Niazi H, Khan MI, Asghar AK. Assessment of Post-Traumatic Stress Disorder and Role of Spirituality Amongst Caregivers of Pediatric Cancer Patients in Pakistan. Life and Science. 2024; 5(1): 33-40. doi: http://doi.org/10.37185/LnS.1.1.440
Effect of Body Mass Index and Ankle Dorsiflexion in Planter Fasciitis Patients; Performance Perspective
Authors: Lata Prem , Hayat Shaista , Kumar Vinesh , Faizan Hassan Muhammad , Batool Sana , Sandeela Khadijatul Ain , Jamil Komal
Published: January 2024

Objective: To determine the effects of body mass index and ankle dorsiflexion in patients with plantar fasciitis.Study Design: A cross-sectional.Place and Duration of Study: The study was carried out at the Department of Physical Therapy of the two leading tertiary care centers, Advance Orthopedic & Reconstructive Institute & Dr. Ziauddin Hospital Karachi, Pakistan from August 2022 to June 2023.Methods: Sixty-Four participants were recruited from the physical therapy departments of two tertiary care centers in Karachi by convenience sampling. The study focuses on the impact of demographics on the performance of plantar fasciitis patients. The measurement tools used in this are BMI (Body mass index), NRS (Numeric rating scale), LEFS (Lower extremity functional scale), and Goniometer. The data were analyzed by SPSS version 23.0. Results: Our findings show that plantar fasciitis is more common in the obese-II category with reference to BMI, females are more affected than males with reference to gender, the middle age group is more affected with reference to age and dorsiflexion angle of patients is less than normal range shows the directly proportional of demographics with the performance of patients with plantar fasciitis.Conclusion: Our study showed the positive effect of ankle dorsiflexion angle and BMI, gender, pain, and age on the physical performance of plantar fasciitis patients.

How to cite this: Lata P, Hayat S, Kumar V, Hassan MF, Batool S, Sandeela KA, Jamil K. Effect of Body Mass Index and Ankle Dorsiflexion in Planter Fascitis Patients; Performance Perspective. Life and Science. 2024; 5(1): 113-119. doi: http://doi.org/10.37185/LnS.1.1.461
The Binding Occupancy of Pro-Hypertrophic Transcription Factors among Cardiac Developmental Enhancers
Authors: Zehra Raza Rabail , Hussain Irfan , Akhtar Fatima , Mumtaz Sara
Published: January 2024

Objective: To check which of the eight pro-hypertrophic transcription factors bind in abundance to a set of 140 functionally confirmed cardiac enhancers aiming to identify potential therapeutic targets for delaying the onset of cardiac hypertrophy. Study Design: Bioinformatics, in-Silico Study.Place and Duration of Study: The study was conducted at the Department of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi, Pakistan, from January 2022 to December 2022.Methods: For experimentally verified human and mouse noncoding regions with gene enhancer activity measured in transgenic mice, VISTA Enhancer Browser was used to obtain 140 cardiac-specific functionally confirmed enhancers. Among these enhancers, transcription factor binding sites were computationally mapped to assess transcription factor occupancy. The binding sites for all eight transcription factors were screened in the collective set of 140 cardiac enhancers via an in-house script. Results: In this study, among a small set of eight pro-hypertrophic transcription factors, occupancy of transcription factor HAND (Heart- And Neural Crest Derivatives-Expressed Protein) was found to be maximum in the collected pool of functionally confirmed cardiac enhancers. Conclusion: The transcription factor HAND was found to have maximum binding occupancy among a set of experimentally confirmed cardiac enhancers.How to cite this: Raza RZ, Hussain I, Akhtar F, Mumtaz S. The Binding Occupancy of Pro-Hypertrophic Transcription Factors among Cardiac Developmental Enhancers. Life and Science. 2024; 5(1): 22-26. doi: http://doi.org/10.37185/LnS.1.1.464
Role of Prophylactic Antibiotics in Preventing Stroke-Associated Pneumonia in Patients with Ischemic Stroke
Authors: Aslam Muhamad Jawad , Amir Muhammad , Sayed Tahir Mukhtar , Hashmat Asif , Hussain Maryam , Fatima Minahil
Published: January 2024

Objective: To compare the frequency of stroke-associated pneumonia in patients given prophylactic antibiotics versus those not given prophylactic antibiotics.Study Design: Comparative Cross-sectional study.Place and Duration of Study: The study was carried out at the Department of Internal Medicine, Combined st st Military Hospital (CMH), Peshawar, Pakistan from 1 August 2022 to 31 January 2023.Methods: We included 250 ischemic stroke patients and divided them into groups A, “Prophylactic group,” and B, “no prophylactic antibiotics group.” Patients were assessed at 7 days after admission for presence of “stroke associated pneumonia (SAP)” through clinical examination and chest X-rays. Data were analyzed using a statistical package for social sciences 22. For qualitative variables, frequency and percentages were used, whereas for quantitative data, the median (IQR) was used as the data were not normally distributed and contained outliers; using the median and IQR can be more appropriate for describing the central tendency and spread of the data compared to the mean and standard deviation.Results: In our study, the median age of the patients was 68(46-83) years. 61 (24.40%) of the patients were male while 189(75.60%) were female. The median BMI was 31 (19-44) kg/m2. Diabetes was present in 123 (49.20%) patients and 96(38.40%) had hypertension. We found that in the the “prophylactic antibiotics” group (A), 9 (7.20%) patients developed SAP, while in the “no prophylactic antibiotics” group (B) frequency of SAP was 34 (27.20%) (p< 0.001).Conclusion: Prophylactic antibiotics used in “ischemic stroke” patients provide better outcomes by reducing the incidence of “stroke-associated pneumonia”. Therefore, it should be given to all patients admitted to the hospital with ischemic CVA.

How to cite this: Aslam MJ, Amir M, Sayed TM, Hashmat A, Hussain M, Fatima M.Role of Prophylactic Antibiotics in Preventing Stroke Associated Pneumonia in Patients with Ischemic Stroke. Life and Science. 2024; 5(1): 82-88. doi: http://doi.org/10.37185/LnS.1.1.465
Evaluation of Restless Leg Syndrome in Patients with Non-Dialysis Dependent Chronic Kidney Disease at Fatima Memorial Hospital Lahore: A Cross-sectional Study
Authors: Basit Bilal , Sabir Omer , Shahid Adnan Hussain , Kanwal Andleeb , Abass Qadri Ghulam , Rizvi Nabiha
Published: January 2024

Objective: To determine the occurrence of restless leg syndrome in individuals with non-dialysis-dependent chronic kidney disease.Study Design: A descriptive cross-sectional study.Place and Duration of Study: The study was carried out at the Outpatient Department (OPD) of Fatima Memorial Hospital, Lahore, Pakistan, from March 2020 to August 2020.Methods: A total of 280 CKD patients not dependent on dialysis were included in the study. The data were collected through interviews containing questions from international restless leg syndrome study group (IRLSSG). Patients were stratified into different stages according to the estimated glomerular filtration rate (eGFR). Restless leg syndrome was diagnosed by analyzing the responses of the interview marked by the examiner. Results: Among 280 patients, 15.7% (n=44) of chronic kidney disease patients were noted to have restless leg syndrome. The syndrome was significantly more frequent in females and was associated with higher CKD stages (Stage V > Stage III and IV). There was no association with either age or BMI.Conclusion: Restless leg syndrome is more common in chronic kidney disease stage V as compared to lower chronic kidney disease stages (III & IV). If untreated, it can affect patients' quality of life and increase the risk of cardiovascular activities.

How to cite this: Basit MB, Sabir O, Shahid AH, Kanwal A, Qadri GA, Rizvi N. Evaluation of Restless Leg Syndrome in Patients with NonDialysis Dependent Chronic Kidney Disease at Fatima Memorial Hospital Lahore: A Cross-sectional study. Life and Science. 2024; 5(1): 95-100.doi: http://doi.org/10.37185/LnS.1.1.516
Diagnostic Accuracy of Serum Cystatin C for Early Detection of Kidney Damage in Patients with Type II Diabetes Mellitus: Bahawalpur, Pakistan
Authors: Sajid Iqra , Saeed Rabia , Goheer Arfa , Asghar Sameen , Saqib Sara , Bashir Fareeha
Published: January 2024

Objective: To determine the diagnostic accuracy of serum Cystatin C for early detection of kidney damage taking albumin Creatinine Ratio as a reference standard among people of Bahawalpur having diabetes mellitus type 2.Study Design: A cross-sectional study.Place and Duration of Study: The Study was conducted at the Department of Pathology in collaboration with th th Kidney Center, Bahawalpur Victoria Hospital, Bahawalpur, Pakistan from 27 August 2021 to 26 February 2022.Methods: There was a total of 200 patients having diabetes mellitus type 2 with GFR between 60-90ml/min with an age range from 40-60 years were selected. Study participants with a history of steroid intake, hypothyroidism, chronic liver disease, AIDS, and hypertension were not included in the study. For assessment of diagnostic accuracy of Cystatin C to evaluate the renal damages in early stages, microalbuminuria was evaluated. As per the guidelines provided by the respective manufacturers, individuals exhibiting two albumin creatinine ratio (ACR) levels exceeding 30 mg/g were classified as having diabetic nephropathy (DN).Results: The overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of serum Cystatin C for the early detection of kidney damage, with albumin-to-creatinine ratio used as the reference standard among individuals with type 2 diabetes mellitus, were 90.98%, 78.21%, 86.72%, 84.72%, and 86.0%, respectively.Conclusion: The findings of this investigation indicate that serum cystatin C (CysC) exhibits a considerable level of diagnostic accuracy in the early detection of kidney damage among individuals with type 2 diabetes mellitus, utilizing the albumin-to-creatinine ratio as a reference standard.How to cite this: Sajid I, Saeed R, Goheer A, Asghar S, Saqib S, Bashir F. Diagnostic Accuracy of Serum Cystatin C for Early Detection of Kidney Damage in Patients with Type II Diabetes Mellitus: Bahawalpur, Pakistan. Life and Science. 2024; 5(1): 41-47. doi: http://doi.org/10.37185/LnS.1.1.559
Clinical Effects of Shugan Jieyu Capsule Combined with Aerobic Exercise on Depression
Authors: Dong Qizheng
Published: January 2024

This study explored the clinical effect of Shugan Jieyu capsule combined with aerobic exercise on depression. One hundred patients with depression were recruited from Zhengzhou Sixth People’s Hospital and were divided into a control group (n = 50) and a research group (n = 50). Patients in the control group received escitalopram alone therapy, while the research group received escitalopram and Shugan Jieyu capsule in conjunction with aerobic exercise. The research group exhibited a better therapeutic effect than the control group (χ2 = 6.06). After therapy, the Hamilton Depression Rating Scale scores of both groups were reduced, and the research group had a lower score than the control group. Following treatment, tumor necrosis factor-α, interleukin-6, and interleukin-2 levels decreased in both groups, and the research group had lower levels than the control group. The Pittsburgh Sleep Quality Index scores of both groups were reduced, with the research group having a lower score than the control group. The score for each item of the World Health Organization Quality of Life in both groups was elevated after therapy, and the research group had a higher score than the control group. In summary, Shugan Jieyu capsule combined with aerobic exercise can decrease the symptoms of depression and inflammatory response, and promote the efficacy of treatment, sleep quality, and quality of life in patients with depression.
Pemanfaatan Limbah Ikan dan Sayuran dari Pasar Kahayan menjadi Silase dengan Sumber Bakteri Asam Laktat yang Berbeda
Authors: Sulistyaningrum Tyas Wara , Araina Elga
Published: January 2024

Penelitian ini bertujuan untuk mengoptimalisasi pemanfaatan limbah ikan khusunya isi perut, kepala dan sisik ikan dan limbah sayuran terutama kubis, sawi hijau dan sawi putih di Pasar Kahayan Kota Palangka Raya dalam upaya untuk mengurangi pencemaran lingkungan karena saat ini limbah tersebut sebagian kecil hanya digunakan sebagai tambahan pakan ternak yang hanya dapat digunakan dalam bentuk segar hingga waktu simpan yang sangat pendek, sementara limbah organik dan anorganik dari lokasi Pasar Kahayan dibuang ke TPA. Untuk itu dilakukan penelitian tentang upaya mengoptimalisasi pemanfaatan limbah tersebut menjadi silase ikan, yaitu sebagai tambahan ransum pakan ternak dengan harapan produk yang dihasilkan mempunyai nilai guna dan nilai ekonomis serta limbah yang terbuang semakin sedikit. Pada penelitian ini parameter pengujian adalah uji kimia, yaitu uji kadar protein dan uji kadar lemak, menggunakan 3 perlakuan yaitu: pembuatan silase dengan penambahan larutan sumber asam laktat dari asinan kubis (A); Pembuatan silase dengan penambahan larutan bakteri asam laktat dari asinan sawi hijau (B); dan pembuatan silase dengan penambahan larutan bakteri asam laktat dari asinan sawi putih (C). Hasil dari penelitian ini diperoleh kandungan protein berkisar antara 32,98-35,75 % dan kandungan lemak pada masing-masing perlakuan berkisar antara 8,13-8,42%.
Assessment of the health benefits of phytochemicals in Cynometra
cauliflora based on an in silico study against Alzheimer’s disease
Authors: Illangasinghe Jagath , de Zoysa Heethaka. Krishantha Sameera , Yapa Neelamani , Bamunuarachchige Thushara Chathuranga , Waisundara Viduranga Yashasvi
Published: January 2024

Aim: Cynometra cauliflora (namnam) belongs to the family Fabaceae and is native to eastern Peninsular Malaysia. It grows well with an annual rainfall of 1,500–2,000 mm. Even though a considerable amount of research has been carried out with C. caulifora, there is a dearth of information about biomolecules that may pave the way for drug discoveries and food supplements, which is a gap addressed in this study.
Methods: The study presented in this paper has identified several antimicrobial, antioxidant, and anti-inflammatory substances, and an in silico approach was used to understand the behaviors of kaempferol-3-O-rhamnoside (K-3-Rh) and β-sitosterol acetate against Alzheimer’s disease (AD). The molecular dynamics (MD) simulations were performed with the selected protein ligand complex of two natural molecules and the synthetic ligand to analyze the dynamic behaviors and binding free energy throughout the 100 ns simulation time. Further, both natural molecules that were investigated comply with Lipinski’s drug-likeness rules.
Results: The docking scores of both K-3-Rh and sitosterol were found to be compatible with the synthetic AD drug molecules [donepezil analogue (H0L)] used as a reference in the study. Hence, the phytochemicals of Cynometra caulifora showed comparatively similar potency against acetylcholinesterase (AChE).
Conclusions: Overall, the potential binding affinity from molecular docking and static thermodynamics features from MD simulation suggest that K-3-Rh and β-sitosterol acetate could be considered as a potential therapeutic lead to inhibit AChE leading for AD treatment.
Equinoterapia en población reclusa: una nueva realidad de reinserción social
Authors: Boria Arias Raquel
Published: January 2024

Numerosos estudios científicos muestran la dificultad de reinserción de la población reclusa. Las cárceles son lugares de internamiento donde las personas privadas de libertad se ven obligadas a adoptar un estilo de vida carcelario durante el tiempo que dure la condena, lo que repercute negativamente no solo en sus vínculos afectivos, debido al aislamiento, sino también a nivel psicológico y cognitivo. Aunque existen leyes que fomentan la reinserción y reintegración social de esta población, se han observado deficiencias que dificultan el alcance de esos objetivos. La presente investigación analiza las consecuencias que acarrean las largas estancias en prisión y los tratamientos e intervenciones que se están llevando a cabo en la actualidad profundizando en una nueva línea de actuación que enfrente esta problemática mediante el uso de Intervenciones Asistidas con Caballos (IAC). Asimismo, se pretende descubrir si estas intervenciones pueden suponer un ámbito de actuación para la Educación Social. Con este fin se ha llevado a cabo una investigación de índole cualitativa y de metodología comunicativa gracias a la cual se ha podido conocer el impacto que generan estas Intervenciones (IAC) no solo a nivel físico sino también a nivel psicológico y social en la población reclusa. Éstas han generado una mejora del autoconcepto, la responsabilidad, el sentido de logro favoreciendo, además, el desarrollo de habilidades psicoemocionales que posteriormente se manifiestan en las relaciones interpersonales. Estos cambios producen, a su vez, una disminución de los índices de reincidencia de este colectivo.
Three-dimensional Finite Element Model of Three-phase Contact Line Dynamics and Dynamic Contact Angle
Authors: Chekhonin Konstantin A. , Vlasenko Victor D.
Published: January 2024

An unconventional model of three-phase contact liny dynamics is suggested for the numerical solution of the boundary value problem of dipping and spreading. The numerical modeling is conducted with the use of the finite-element method in Lagrange variables. The mathematical model of the process is described by the equation of motion, continuity, and natural boundary conditions on the free surface. To exclude the ity of viscous stresses in the mathematical model on three-phase contact lines (TPCL) there was suggested a gridded model of gliding that takes into consideration peculiarities of dissipative processes in the neighborhood of TPCL at the microlevel. To reduce oscillations of pressure in the neighborhood of TPCL, a finite element is used. The suggested method allows for natural monitoring of free surface and TPCL with an unconventional model for dynamic contact micro-angle. A stable convergent algorithm is suggested that is not dependent on the grid step size and that is tested through the example of a three-dimensional semispherical drop and a drop in the form of a cube. The investigations obtained are compared to well-known experimental and analytical results demonstrating a high efficiency of the suggested model of TPCL dynamics at small values of capillary number.
The Impact of IFRS Mandatory Adoption on the Performance of Saudi Banks
Authors: Mohammad Mona Hassabelrasoul , Shehab Lamia S. , Turki Hela , Ali Zahra Tajuddin Abdelgader
Published: January 2024

The study aims to determine the impact of IFRS mandatory application on financial and market performance, in the Saudi Arabian banking sector for the period from 2012 to 2021. The results of this study show that there is no relationship between the IFRS mandatory application and each of the rates, return on equity, and return on assets, while there is an inverse relationship with earnings per share. In terms of the effect on the market performance, the study concluded that there is no relationship between the IFRS mandatory application and each of the volume and value of trading, and there is a positive relationship on the growth rate. The study attributed these results to several reasons, the most important of which is the gradual application of the IFRS, which was followed by Saudi Arabia, in accordance with strict executive procedures from the Saudi Arabian Monetary Authority (SAMA).
Positiivinen näkökulma konfliktijohtamiseen – esimiesten onnistumiset ristiriitatilanteiden ratkaisussa
Authors: Salmi Ilkka , Perttula Juha , Syväjärvi Antti
Published: January 2024

A positive view on conflict management – resolving conflict situations successfullyThis research aims to reveal managers’ conceptions about the successful ways of resolving conflict situations between employees. The research question is “What conceptions do managers associate with the successful ways of resolving conflict situations between employees? ” The research data was collected through a questionnaire posted to managers in the public health care sector. Out of 47 managers, 20 responded to the questionnaire. Eventually, 19 responses were included in the analysis, which we conducted using the phenomenographic approach. On the basis of the analysis, the following three description categories were formed: a manager’s own action; cooperation between a manager and both parties of a conflict; and a resolution by a third party. A manager’s interaction and attitude proved to be important factors in resolving conflicts. Using the accrued data, we formed four classes – diplomatic, assertive, empathic, and delegative
Placenta peptides: antibacterial effects
Authors: Torshin I. Yu. , Bogacheva T. E. , Gromova O. A.
Published: January 2024

Mass spectrometric sequencing of peptides in Laennec indicated the presence of 5 peptides in the drug, the biological activity of which may determine the antibacterial properties of the drug. The most significant result of this study is the presence in Laennec of a fragment of the antibacterial peptide cathelicidin (LL-37), an important vitamin D-dependent factor of innate immunity. Other Laennec peptides help reduce excess inflammation by inhibiting the activity of the NF-kB protein, which mediates the effects of TNF-α.
Study of the effectiveness of the drug Laennek in case of liver damage by palm oil in rats
Authors: Bogacheva T. E. , Kalacheva A. G. , Gromova O. A. , Torshin I. Yu. , Grishina T. R. , Demidov V. I.
Published: January 2024

Palm oil is a component of most food products, characterized by a high content of palmitic and oleic acids, an excess of which leads to the formation of tripalmitins, practically do not respond to enzymatic hydrolysis by lipoprotein lipase and predetermine the development of obesity, type 2 diabetes mellitus and atherosclerosis. This paper presents the results of a study of the drug Laennek, produced on the basis of standardized hydrolysates of the human placenta (HRP). The use of HRP under the influence of excessive consumption of palm oil in the diet led to a significant decrease in markers of liver dysfunction (ALT), which increase with an enriched diet of refined palm oil (bilirubin, total protein, ALT, AST). The hepatoprotective effect of Laennek was confirmed by the results of histological and biochemical studies indicating a decrease in the severity and prevalence of fatty liver dystrophy.
Effectiveness of Incorporating Film Adaptations in EFL Literature Courses: A Case Study in Saudi Arabia
Authors: Azhar Hadeel
Published: January 2024

line with the recent and ongoing technological changes in Saudi Arabia, which place greater emphasis on cinema and film adaptations, this study aimed to investigate the effect of incorporating films and visual media into literature courses on students’ understanding of and motivation towards literary texts. The participants were 41 fourth-level female students in the Department of English at Umm Al-Qura University, Saudi Arabia. The treatment group (n=21) read Henrik Ibsen’s play A Doll’s House (1879) and watched the adapted film, whereas the control group (n=20) was asked to only read the play and discuss it in class. The findings revealed that the treatment group performed better in terms of answering questions about play after watching the film adaptation. It is suggested that incorporating film adaptations into literature courses has a positive impact on English as a foreign language students’ understanding of assigned literary texts. This research adds a new case study to the expanding literature. Limitations and future research directions are discussed.
KEYWORDS
English language, literary texts, motivational tools, students’ comprehension, teaching methods, visual media
Kinds, properties and atelicity
Authors: Chierchia Gennaro
Published: January 2024

Since at least Vendler 1967, one of the most widely discussed data points, often viewed as the ultimate test for (a)telicity, is the behavior of durative modifiers with respect to different VP types as in John killed mosquitos/*a mosquito for an hour. In the present paper, I explore a new blend of the two most widespread approaches to this issue, namely (i) the view of durative modifiers as universal quantifiers (e.g., Dowty 1979, a.o.) and (ii) their view as aspect sensitive measure adverbials (e.g., Krifka 1998, a.o.).  The blend explored here is based on an economy constraint specific to the scope of adverbial quantification (‘do not weaken’ cf. Bassa Vanrell 2017) combined with the identification of the special role that kinds and properties may play as direct bearers of thematic relations in an event-based semantics.
Bivariate Time Series Analysis of Nigeria Gross Domestics Product and Communication Sector
Authors: Ekpe Anyanime Udo , Usoro Anthony Effiong , Ekong Akaninyene Okon
Published: January 2024

The need to establish a relation between Gross Domestic Product and Communication sector was the major focus of this research. This research work investigated the contribution of Communication sector to the Gross Domestic product of Nigeria Economy. With the aid of ACF and PACF, ARIMA (1 1 1) was suggested for both variables. Alternative multivariate time series models used for the analysis were ARIMAV, MARDL and MARDL-MA models. The research has established interaction and interdependence between the two macroeconomic variables, and has also revealed that each of the variable has contributed significantly to each other at first time lag. The error variances of the bivariate time series model were derived for GDP and Communication sector. When comparing the three models for the two economic variables, ARIMAV model for Gross Domestic Product has the least error variance of 0.2183 making it the best model, while MARDL model for communication sector produced the least error variance of 0.0723, thereby indicating that MARDL model outperformed ARIMAV and MARDL-MA models for communication sector. Hence, this research has brought to focus the fact that performance of a model over another is predicated upon the nature of the economic data. That means there is no fixed multivariate time series model for a given macroeconomic data due to the dynamic nature of the time series.
Awareness and Utilisation of Family Planning Among Postpartum Women in Ondo State, Nigeria
Authors: Abiodun-Ojo Olubukola Esther , Alo Oluwatosin Blessing , Akinyemi Oluwatoyin Olajumoke , Dele-Alonge Olajumoke Ileola , Maitanmi Julius Olatade , Maitanmi Bukola Titilope
Published: January 2024

This study investigates the awareness and utilisation of family planning among postpartum women attending postnatal clinics in selected health centers in Ifedore Local Government, Ondo State. The objectives include determining sources of information, examining common methods used, and assessing knowledge, utilisation, and perceived attitudes of workers regarding family planning. A descriptive design was employed, and the target population comprised women aged 15 to 49, 1 week–12 months postpartum, accessing child health services from three selected health centers. The sample size of 234 was determined using Cochran’s formula, with data collected through a self-structured questionnaire. Validity and reliability were ensured through expert assessment and a pilot study. Analysis using SPSS 27.0 involved percentages, tables, and chi-square tests. The findings revealed commendable understanding of family planning services among women of reproductive age, although utilisation remained inadequate. Factors contributing to this included low socioeconomic status, religious beliefs, and limited education. Despite these challenges, the study highlights the potential for positive outcomes in the future, emphasizing the importance of comprehensive understanding of family planning services. Recommendations include enhancing community education on the benefits of smaller families and women empowerment, promoting gender balance, and emphasizing immediate initiation of family planning postpartum in healthcare settings. These initiatives aim to address barriers and promote the use of family planning methods among women in the study area.
Sperm Switch: A New Trend in Reducing Maternal Mortality
Authors: Awe Olabisi Olayinka , Fadare Risikat Idowu
Published: January 2024

The study looked at the emerging practice of switching sperm to reduce maternal mortality in Ekiti State. Secondary data from the chosen health facilities in Ekiti State was used in the study. The major beneficiaries of family planning programs have historically been women, and men have been seen as the services' invisible partners. The study's ideas included male involvement in family planning, the effect caused by sperm switching on family planning, its difficulties, ways to use sperm switching to lower maternal death rates, and the responsibilities of midwives and the government in the process. The study's implications for nursing practice are that nurses and midwives undergoing training should be able to apply the sperm switch approach, and nurses should conduct additional research on new trends in family planning, particularly sperm switching, as well as the advantages of male involvement in family planning. The suggestion is that political commitment, priorities, effective governance, and enough financing should be given top priority. In addition, men should receive advice regarding the reversibility of the sperm switch method, and more awareness should be raised regarding the sperm switch strategy's positive effects on health when used with male contraceptives for family planning.
Revisión del Abordaje Odontológico de las Fracturas Maxilomandibulares
Authors: González Ordoñez Teresa Veronica , Rodríguez Largo Arturo Andrés , Flores Oña Cristian Andrés , Caiza Iza Franklin Orlando , Morante Ruiz Emely Denisse
Published: January 2024

Objetivo: describir el actual abordaje odontológico de las fracturas maxilomandibulares. Metodología: se realiza una revisión bibliográfica en Pubmed, Web Of Science, Cochrane con los términos indexados en español: “Fracturas Maxilomandibulares” y “Tratamiento”, junto a sus términos indexados en inglés: “Jaw Fractures” y “Therapy”, en los últimos 6 años (2018-2024). Resultados y discusión: el limitado número de publicaciones refleja una brecha significativa en la investigación. Conocer la clasificación de estas fracturas es fundamental para guiar el manejo clínico y quirúrgico, la clasificación de Le Fort para fracturas del maxilar superior y la clasificación de mandíbula de la AO para fracturas mandibulares, dos de las más ampliamente reconocidas. El manejo de las fracturas maxilares y mandibulares implica una evaluación exhaustiva para determinar un abordaje conservador o quirúrgico, con la finalidad de garantizar las funciones propias, la armonía facial y evitar futuras complicaciones. Conclusión: el manejo de las fracturas maxilomandibulares implica una comprensión profunda de la clasificación, evaluación cuidadosa de la extensión y gravedad de la lesión, y la aplicación de estrategias de tratamiento personalizadas. La colaboración entre cirujanos maxilofaciales, ortodoncistas y otros profesionales de la salud es esencial para garantizar resultados óptimos y la restauración completa de la función y la estética facial.
Meningitis Criptocòcica en Paciente Masculino De 40 Años con Comorbilidades. Reporte de Caso
Authors: San Andrés Tuárez Camila Alexandra , Paz Marín Carlos Andrés , Banda Tapia Daniel Andrés , Muñoz Galarza Cinthya Lorena , Sotomayor Neumane Gabriel Alejandro , Carrión Granda Carlos Andrés
Published: January 2024

La meningitis criptocócica es una de las principales causas de meningitis en muchos países de ingresos bajos y medios y es una infección grave del sistema nervioso central que también representa un importante problema de salud pública debido a la alta mortalidad y la discapacidad a largo plazo, el diagnóstico rápido de la infección y la intervención terapéutica temprana son cruciales para mejorar las tasas de supervivencia y la calidad de vida de estos pacientes. La criptococosis es una levadura encapsulada que afecta a humanos y animales y se adquiere por inhalación de agentes infecciosos de la especie Cryptococcus neoformans y el menos común Cryptococcus gattii. La criptococosis meníngea tiene una alta prevalencia en todo el mundo y afecta particularmente a pacientes infectados por VIH con recuentos bajos de CD4 y a personas que reciben terapia inmunosupresora. Paciente de 40 años con antecedentes de Lupus eritematoso sistémico, se evidencia alteración del estado de conciencia acompañado de cefalea de 7 días de evolución, motivo por el cual acude a la casa de salud mas cercana.
Estereotipos Negativos Hacia la vejez en Estudiantes de Medicina de Pregrado
Authors: López Vargas Javier , Nuñez Bautista Cristian Adrián , Rodea Solares Gala Fabiana , Nájera Espinosa Leticia Carolina
Published: January 2024

El objetivo de la presente investigación fue estimar el nivel de estereotipos negativos hacia la vejez en estudiantes de medicina de pregrado. Se realizó un estudio de tipo descriptivo y transversal. La muestra estuvo conformada por un total de 215 estudiantes de pregrado de medicina, 165 mujeres y 50 hombres. Se utilizo el cuestionario de estereotipos negativos hacia la vejez (CENVE) el cual está constituido por 15 ítems y cuenta con tres factores: Salud, Motivación-Social y Carácter-Personalidad. Se obtuvo una media de 36.67 en el CENVE el cual indica que existe un nivel bajo de estereotipos negativos hacia la vejez. Se concluye que los estereotipos negativos hacia la vejez se encuentran en un nivel bajo en la muestra estudiada, pues se obtuvo un puntaje general bajo. Asimismo, para las tres dimensiones: Salud, Motivación-Social y Carácter-Personalidad se obtuvieron puntajes bajos en ambos sexos.
La Importancia de la Nutrición en el Manejo de la Obesidad Infantil: Un Estudio de Revisión
Authors: Ortiz Sánchez Erick Alexander , Hidalgo Morales Kattyta Patricia
Published: January 2024

Según la OMS (2), la obesidad es “una enfermedad crónica que se caracteriza por el exceso de grasa en el organismo, en un niño se considera que es obeso cuando su peso sobrepasa el 20% de su ideal, mientras que en un adulto es cuando el índice de masa corporal es mayor de 30 kg/m²”. Es por ello que se la considera como una enfermedad crónica, compleja y multifactorial, que generalmente aparece en la infancia y adolescencia que puede tener cierta predisposición genética y ambiental. Por ello, el propósito del presente estudio fue elaborar una revisión bibliográfica referente a la importancia de la nutrición en el manejo de la obesidad infantil, además de cómo prevenirlo a través una buena alimentación desde edades tempranas.  Se realizaron búsquedas en sitios como PubMed, MDPI, Dialnet y Google Scholar desde el 12 de julio del 2023 al En la cual, se incluyó, 30 artículos publicados desde el año 2018 y 2023; a partir de los cuales se logró describir los índices y estadísticas de la obesidad infantil, así como, la importancia de una buena alimentación acompañada de ejercicio para mantener una buena salud. Por otro lado de determinó la niñez, es la edad perfecta para crear hábitos alimenticios adecuados, ya que una dieta equilibrada es fundamental para el desarrollo y fortalecimiento del sistema inmunológico; muchos de los problemas de salud que se llegan a presentar en la adultez se encuentran ligadas a una alimentación deficiente durante la infancia.
Mount Faifa, a local hotspot of butterfly diversity (Lepidoptera: Papilionoidea) in the Kingdom of Saudi Arabia
Authors: Verovnik Rudi , Kosmač Marko , Ishag Alrabea A. E. , Al Dhafer Hathal M. , Seizmair Michael
Published: January 2024

During four surveys in 2022 and 2023, we studied the butterfly fauna of Mt. Faifa at 25 locations situated mainly on the wooded north western side of the mountain. A total of 75 species were recorded, bringing the species count for the mountain to 82, which represents 65 % of the butterfly fauna of Saudi Arabia. Several rare species were recorded including Lepidochrysops haveni, which is reported in Saudi Arabia for the first time. Given the proximity of the African continent, widespread Pan-African species dominate the biogeographic composition. There are only a few montane species present on Mt. Faifa, and both mid-elevation maximum and a decline in butterfly richness towards the higher altitudes was noticeable. This mountain could be considered a hot spot of butterfly diversity, thus some efforts should be made to preserve the remaining woodlands and other butterfly-rich habitats.
The peace formula of Volodymyr Zelenskyy before and after the Vilnius NATO summit
Authors: Hryhorii Perepelytsia Hryhorii Perepelytsia
Published: January 2024

Abstract. The Peace Formula put forward by Volodymyr Zelenskyy at the G20 Summit was a response to the challenges caused by the russian-Ukrainian war and the destruction of the existing world order that followed it. Undoubtedly, the Formula stirred great resonance both among diplomatic circles and the entire international environment since the old system of regional and global security was destroyed, and the global world now faced the problem of finding the contours of a new architecture of international security. Therefore, the Formula represented an attempt to simultaneously solve a whole set of different-scale and multi-directional strategic tasks: urgent and long-term, regional and global, etc. The level of priority of those tasks depends not just on the course and outcome of russian-Ukrainian war but also on the challenges and threats that subsequently emerged at the global level of international security.

The article describes the conditions and factors that preceded the emergence of the Peace Formula, as well as the process of filling the sessions and content of the document. The author emphasises the Formula’s significance for potential negotiations with russia to end the war and analyses the positions of key geopolitical actors regarding the implementation of the Peace Formula and its role in formulating security guarantees for Ukraine. Other aspects covered in the study include the influence of the decisions of the Vilnius NATO Summit on the fulfilment of the items of the Peace Formula, the prospects of security guarantees for Ukraine, and the ultimate formation of a new regional security architecture.

Key words: Peace Formula, security guarantees, NATO, regional security.
The Effectiveness of the Regional Regulation Formation Agency in Producing Initiative Regional Regulations
Authors: Tulangow Deo Jeremy , Mangindaan Joanne V. , Londa Very Y.
Published: January 2024

This research aims to analyze the effectiveness of the Regional Regulation Formation Agency in Producing Initiative Regional Regulations in the DPRD of North Sulawesi. This research uses the theory of Richard M. Steers with measures of effectiveness, namely goal achievement, integration and adaptation. This research used a qualitative descriptive method with 4 informants consisting of the deputy chairman of the DPRD of North Sulawesi, the chairman of BAPEMPERDA (Regional Regulation Establishment Agency), members of BAPEMPERDA, and BAPEMPERDA staff. The results of this research show that the performance of BAPEMPERDA is still not optimal, seen from the lack of effectiveness in making regional regulations, to the point that they do not reach directly to the community. Based on research findings, several things that need to be suggested to the DPRD (Regional People's Representative Council), especially BAPEMPERDA North Sulawesi, are the need for commitment from DPRD members so that a regional regulation can be effective, not only in terms of quality, but can be felt by the constituents, namely the community.