bluuebunny/crossref_metadata_2025 huggingface dataset:
FATE OF MILK YIELD AND FERTILITY PARAMETERS IN HOLSTEIN DAIRY COWS SIMULTANEOUSLY EXPOSED TO ZEARALENONE, DEOXYNIVALENOL AND FUMONISIN B1 MYCOTOXICITY
Authors: Uyarlar C , Yilmaz O
Published: April 2024

This study was planned to investigate the effect of zearalenone (ZEA), deoxynivalenol (DON) and Fumonisin B1 (FB1) on blood metabolites, milk yield, estrous activity, pregnancy rate and uterine health in 486 heads of Holstein dairy cows. For this purpose, the data collected from the animals were divided into the four periods as follows: feeding with non-contaminated diet for 30 days (pre-contamination period), contaminated diet for 60 days (contamination period), contaminated diet supplemented with mycotoxin adsorbent for 30 days (adsorbent period) and the diet after removing the contaminated feedstuffs for 30 days (non-contamination period). Each feedstuff was analysed in contamination period and at the beginning of the non-contamination period to determine the presence or absence of ZEA, DON and FB1 in the diet. The blood metabolic profile was assessed in 21 animals in 1-10 days in milk, selected through cluster random sampling method while milk yield, estrous activity, pregnancy rate and prevalence of metritis/endometritis were compared among all four periods. The milk yield (P≤0.001) and milk fat (P≤0.05) in the contaminated period were low as compared to other periods. The concentrations of beta-hydroxybutyric acid (p≤0.001), non-esterified fatty acids (P≤0.05), gamma-glutamyl transferase (P≤0.05), and blood urea nitrogen (P≤0.001) parameters were significantly higher, while the glucose (P≤0.001) and triglycerides (P≤0.05) were lower in the contamination period, as compared to adsorbent and non-contamination periods. The pregnancy rate through artificial insemination decreased significantly during the contamination period (P≤0.05) as compared to pre-contamination period. The overall pregnancy rate in the pre-contamination period was also significantly decreased as compared to the adsorbent and non-contamination periods (P≤0.001). The percentage of type III anestrus were significantly lower during the non-contamination period (P≤0.05). The percentages of cows with metritis during the non-contamination period was significantly lower (p≤0.05) as compared to the contamination period. It was concluded that the routine feed analysis was necessary to determine the presence of ZEA, DON and FB1. Moreover, mycotoxin binder supplementation and/or removing contaminated feedstuffs from the diet under mycotoxicosis conditions may prevent the severe negative energy balance and improve the milk yield and fertility parameters.
Keywords: DON, ZEA, Fuminosins, Metabolic Parameters, Milk Yield, Fertility, Holstein
Digital Collage Design Through The Concept of Linear Time in The Documentary Film "Nasida Ria: Sun Stage" (2023) by Wisnu Candra
Authors: Wisnu Candra Mohammad , Armantono R. B.
Published: April 2024

Not only recording reality, the form of documentary films today has undergone significant development. One of the drivers of development is the digital phenomenon. Digitalization is not an impact, but a phenomenon that must be adapted as best as possible and addressed as wisely as possible. The purpose of this development is to provide innovation in the form of documentary films that are more innovative and creative. Qualitative method is used as the epistemology of data collection through research to validate the truth of the subject. Meanwhile, the principle of cross-disciplinary collaboration between film directors and digital collage artists is used as a foundation to produce a visual identity for the film to be more innovative and creative. As a result, the short film "Nasida Ria: Sun Stage" is not only a film that records the history of Nasida Ria, but also a contribution to the evolution of the documentary film form. Through an archive of texts, photos and videos arranged using digital collage techniques and moved linearly.
Influence of Drying Parameters and Methods of Fractionation in the Chemical Composition of Dehydrated Ginger (Zingiber Officinale Roscoe)
Authors: Cristofel Cristian Jose , Catharina Weis Cláudia Moreira Santa , Vaz Goncalves Giovanna Camile , Treichel Helen , Bertan Larissa Canhadas , Tormen Luciano
Published: April 2024

Ginger is widely commercialized in the food, chemical, and pharmaceutical industries, mainly in dehydrated and powdered form. To do this, the raw material must go through a drying process, which can significantly influence its characteristics. This study proposed to investigate the ginger dehydration process under three different fractionation methods: whole, sliced, and grated, and subjected to three other drying processes: oven with forced air circulation and renewal (CC) and without forced air circulation and regeneration (SC), both for temperatures of 50, 60, 70 and 80 °C, and freeze-drying. The data obtained allowed the construction of drying curves depending on time. The samples were analyzed for color, phenolic compounds, substances reactive to thiobarbituric acid (TBARS), acidity titratable capacity, 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity, and chemical composition of the oils essential, obtained by hydrodistillation. The ginger drying kinetics shows that the process efficiency is maximized by combining parameters such as more significant sample fractionation, high temperatures, and forced air circulation. Notably, the preservation of bioactive compounds is more effective under conditions of lower temperature, lower fractionation, and absence of forced air circulation, highlighting the importance of these factors in maintaining the nutritional properties of ginger. The evaluation of the essential oil reinforces the need for appropriate strategies, such as freeze-drying or drying in an oven with forced air circulation at 50 °C, to minimize the degradation of volatile components, contributing to optimizing ginger dehydration processes promoting and preserving its nutritional and functional benefits.
Helicobacter pylori and gastric cancer: a critical approach to who really needs eradication
Authors: Kouroumalis Elias , Tsomidis Ioannis , Voumvouraki Argyro
Published: April 2024

It is generally accepted that eradication of Helicobacter pylori (H. pylori) infection may reduce the risk of the development of gastric cancer. Recommendations for global generalized tests and treat all individuals detected positive for H. pylori infection are currently proposed. However, the bacterium is commensal and harmless for the vast majority of the infected population. Moreover, eradication may have detrimental consequences in several groups of patients. In the present review, the current epidemiological data and recommendations for eradication in connection with the possible beneficial effects of the colonization with H. pylori in diseases such as asthma and allergies or chronic gastro-intestinal disorders such as inflammatory bowel disease and Barrett’ esophagus are presented the problems with increasing antibiotic resistance were also examined. Specific groups of patients where eradication of H. pylori may be necessary and endoscopic surveillance is advised were identified. Finally, based on the paradox of high H. pylori prevalence and low gastric risk as reported for areas of Africa, Asia, South America, and Greece, alternatives that may replace the widespread eradication of H. pylori with equal if not better results and more prudent use of the available financial resources are proposed. Mediterranean diets and alcohol and smoking reduction are among the well documented alternatives.
Vessel Dynamic Positioning System Mathematical Model
Authors: Simanenkov Andrii , Doshchenko Halyna , Chymshyr Valentyn , Kononenko Andrii , Terzi Hanna , Smyrnova Iryna
Published: April 2024

This study aims to examine two potential approaches for addressing the challenge of synthesizing control laws in the Dynamic Positioning (DP) system. Both approaches pertain to the same ship model but are rooted in distinct ideologies concerning how to account for the influence of external disturbances on a closed system. The findings of this investigation could offer valuable insights for enhancing DP systems and formulating more efficient management strategies in maritime conditions. The research delves into the structure and principles of the DP system as a sophisticated control complex, identifying associated challenges in its application. Despite numerous implemented projects and considerable developer efforts, sustaining a ship in a specified position during rough seas remains a formidable task, partly due to the ship’s lack of energy armament. Exploration in the realm of regulatory system development has yet to yield the anticipated results. The present study constructs a mathematical model depicting the dynamics of a ship during positioning, considering two versions of automatic control laws aimed at stabilizing the ship’s position. The second model demonstrates superior efficiency in the control system, surpassing the first by at least 14%. A comparative analysis of two control system options with filtering properties in dynamic positioning mode for the vessel was conducted. For better results, it is recommended to implement filtering on the relevant data source before this procedure on a specific data consumer. This preliminary testing helps to remove duplicate and inaccurate data, reducing the load on the data link. Final filtering should be performed on high-performance systems. In summary, the originality and novelty of this article stem from its comparative analysis of control laws, exploration of DP system dynamics, acknowledgment of existing challenges, and practical recommendations for data filtering in dynamic positioning. The study brings a tangible contribution to the field, paving the way for advancements in the development of DP systems management and control methods.
A Comparative Analysis on Proportional-Integral and Fuzzy-Logic Control Strategies for Doubly-Fed Induction Generators
Authors: Padamata Ankineedu Prasad , Rao Gudapati Sambasiva
Published: April 2024

This research investigates superior control methods for optimize the performance of Doubly-Fed Induction Generators in wind energy conversion systems. This proposed work, compares the well-established Proportional-Integral controller, with a Fuzzy Logic controller, known for its effectiveness in managing non-linear systems. To achieve a thorough analysis, this research develops a detailed mathematical model, specifically adopted to the DFIG system. It employs a PI controller for both the rotor-side and grid-side converters of the DFIG system. To enhance performance, a Fuzzy Logic controller is introduced to replace the PI controller, based on real-time operating conditions and gain values. Extensive simulations evaluate rigorously various performance metrics of the DFIG system under different control strategies. This analysis provides valuable insights to guide the selection of optimal control techniques, for wind energy systems using DFIGs. The analysis contributes to advancements in reliability, and efficiency for DFIG-based wind-energy systems, furthering the development of sustainable energy solutions.
Using a Flywheel to Stabilize a Self-Balancing Bicycle
Authors: Siller-Alcalá I. I. , Liceaga-Castro J. U. , Alcántara-Ramírez R. A. , Calzadilla-Ayala S.
Published: April 2024

The designs of two linear control systems approach to stabilize the balance of an unmanned bicycle system are presented. Both approaches are based on the use of a reaction wheel or flywheel to balance the bicycle. The two linear control approaches, based on the linearization of a nonlinear model obtained using Lagrange formalism, are the classic linear controllers, PID and State Feedback control. The performance of both controllers is verified by digital simulation and real-time experimental results.
A Tall Summit: Securing Lasting, Reliable Public Access For Recreational Use On Colorado’s Privately Owned Fourteeners
Authors: Betrus Michael
Published: April 2024

From the National Scenic Trails to mountains to other destinations in nature drawing the public’s interest and time for recreational activities, privately owned land can cause difficulties in ensuring reliable and consistent public access. A specific example is the Decalibron Loop, a trail in Colorado linking together a few mountains; public access has wavered over the years, and a recent Tenth Circuit case, Nelson v. United States, greatly affected landowner dispositions—particularly with regard to liability—toward the privately owned property. Similar situations across the country provide a variety of potential approaches to helping provide public access and reducing landowner concerns.

With the goals of respecting private property ownership and addressing landowner concerns, this Comment explores and analyzes various potential solutions as applied to the Decalibron Loop. Actions such as creating new easements or utilizing the government’s power of eminent domain have significant weaknesses. Creating a reliable partnership and updating the Colorado Recreational Use Statute are the two most viable options. These solutions take into account landowners’ vocal concerns, local organizations’ opinions and insight, and the uncertain future in this area of law following the Nelson case.
НАУКОВИЙ І МЕТОДИЧНИЙ СУПРОВІД РОЗВИТКУ УНІВЕРСИТЕТІВ СВІТОВОГО КЛАСУ: фундаментальні результати Інституту вищої освіти НАПН України для функціонування і розвитку закладів вищої освіти
Authors: Lugovyi Volodymyr
Published: April 2024

У статті підсумовані наукові здобутки вчених НАПН України, насамперед Інституту вищої освіти, як основної наукової установи у сфері вищої освіти, що важливі для розвитку університетів світового класу (УСК). Інститут ровесник Болонського процесу і в цьому році відзначає 25-річчя, за цей час пройшов трансформацію від галузево до проблемно орієнтованої установи, активно формує науку про університети (університетологію), для оприлюднення дослідницьких здобутків заснував наукові фахові видання «Університети і лідерство» та «Філософія освіти», публікує монографії, аналітичні матеріали тощо. На підставі наукових результатів сформульовано методичні рекомендації із створення умов для успішного становлення УСК в Україні, що важливо для повоєнного відновлення країни, підвищення її обороноздатності та прискорення євроінтеграції.
Vaccinoprophylaxis of infections and activity of immuno-inflammatory rheumatic diseases: pro et contra
Authors: Belov B. S. , Muravyeva N. V.
Published: April 2024

In modern conditions, patients with immuno-inflammatory rheumatic diseases (IIRD) are at significant risk of influenza, pneumococcal and herpes viral infections, as well as COVID-19, in some cases fatal. The most effective way to prevent infectious diseases and reduce mortality from them is vaccination, which is recommended in the inactive phase of IIRD. However, a number of patients with IIRD have a refractory course of the disease, and achieving remission in them turns out to be a difficult task, and therefore the problem of vaccination of such patients against the background of an active inflammatory process is very relevant. The review analyzes data on the use of vaccine prophylaxis for the above infections in the active phase of IIRD. In the vast majority of cases, vaccination was safe and did not lead to an exacerbation of IIRD or the development of new autoimmune phenomena.
Güncel Periodontoloji Çalışmaları III
Authors: Gürbüz Ezgi , Kaçar Zeki , Karabıyık Damla Kan , Kavruk Fatma , Önder Yasemin Beliz , Altındal Dicle , Saraç Atagün Özlem , Çetin Özdemir Eda , Bilen Emrah , Dursun Zahitovic Hamide , Bıyıkoğlu Başak , Tekin Tümer , Gül Sema Nur Sevinç , Has Ladise Ceylin , Naderlou Faezeh , Tavan Egemen , Gökmenoğlu Ceren
Published: April 2024

Gingival Ünite Greftinin Periodontal Plastik Cerrahide Kullanımı
Ezgi GÜRBÜZ
Zeki KAÇAR
Damla Kan KARABIYIK
Fatma KAVRUK
Gerodontoloji ve Periodontal Durum
Yasemin Beliz ÖNDER
Dicle ALTINDAL
Dental Mikrocerrahinin Gelişimi ve Periodontolojide Kullanımı
Özlem SARAÇ ATAGÜN
Periodontal Doku Mühendisliğinde Yeni Yaklaşımlar
Eda ÇETİN ÖZDEMİR
İmplant Tedavisi Açısından Canalis Sinuosusun Konik Işınlı Bilgisayarlı Tomografi ile Değerlendirilmesi
Emrah BİLEN
Hamide DURSUN ZAHİTOVİC
Periodontitis ve Romatoid Artrit
Başak BIYIKOĞLU
Tümer TEKİN
Dental İmplant Başarısızlığının Etiyolojisi ve Yönetimi
Sema Nur Sevinç GÜL
Ladise Ceylin HAS
Endodontik Periodontal Lezyonlar
Sema Nur SEVİNÇ GÜL
Faezeh NADERLOU
Dişeti Çekilmelerinde Güncel Tedavi Yaklaşımları
Egemen TAYAN
Periodontal Hastalıklar ve Covid-19 Arasındaki İlişki
Egemen TAYAN
Ceren GÖKMENOĞLU
Discovery and biosynthesis of bacterial drimane-type sesquiterpenoids from Streptomyces clavuligerus
Authors: Zhang Dongxu , Du Wenyu , Pan Xingming , Lin Xiaoxu , Li Fang-Ru , Wang Qingling , Yang Qian , Xu Hui-Min , Dong Liao-Bin
Published: April 2024

Drimane-type sesquiterpenoids (DMTs) are characterized by a distinctive 6/6 bicyclic skeleton comprising the A and B rings. While DMTs are commonly found in fungi and plants, their presence in bacteria has not been reported. Moreover, the biosynthetic pathways for DMTs have been primarily elucidated in fungi, with identified P450s only acting on the B ring. In this study, we isolated and characterized three bacterial DMTs, namely 3β-hydroxydrimenol (2), 2α-hydroxydrimenol (3), and 3-ketodrimenol (4), from Streptomyces clavuligerus. Through genome mining and heterologous expression, we identified a cav biosynthetic gene cluster responsible for the biosynthesis of DMTs 2–4, along with a P450, CavA, responsible for introducing the C-2 and C-3 hydroxy groups. Furthermore, the substrate scope of CavA revealed its ability to hydroxylate drimenol analogs. This discovery not only broadens the known chemical diversity of DMTs from bacteria, but also provides new insights into DMT biosynthesis in bacteria.
Communicating The Smart City Concept to The SME Community
Authors: Arifin Pupung , Amanda Putri Jessica
Published: April 2024

The smart city concept has been used by many cities in Indonesia as means to ease people lives. Yogyakarta, as the province with the highest ratio of area and number of tourism visits in Indonesia, is a province that has been quite hit by the COVID-19 pandemic. One of the affected parties are Small and Medium Enterprises (SMEs). To anticipate this, the Yogyakarta City Government launched the Jogja Smart Service (JSS) application. JSS was launched with the aim of facilitating public services, and one of its features namely Gandeng Gendong to bring together the SMEs community with potential buyers. This paper will describe the communication process of JSS application by Yogyakarta City Government and SMEs actors. This research departs from the impact of the Covid-19 pandemic felt by the SMEs of Yogyakarta City on the economy in their lives. After the pandemic, the Yogyakarta City Government tried to foster smart economy as one of the smart city branch concepts. Nonetheless, there are still many challenges. In anticipation of a repeat of the economic impact of the COVID-19 pandemic, the SMEs actors must be able to quickly adopt the Jogja Smart Service application. The results of the research obtained are the process of communication by Yogyakarta City Government and SMEs actors in the early majority stage. The SMEs actors are at the confirmation stage. The confirmation determines that SMEs actors continue to use the Jogja Smart Service application but need more socialization and training.
Hepatics from Rovno amber (Ukraine). 11. Radula oblongifolia and R. tikhomirovae sp. nov.
Authors: Mamontov Yuriy S. , Ignatov Michael S. , Vasilenko Dmitry V. , Legalov Andrei A. , Perkovsky Evgeny E.
Published: April 2024

A study of Rovno amber has revealed two fossil leafy liverwort species of the genus Radula (Radulaceae, Marchantiophyta) that are new to the late Eocene flora of Rovno amber. One of these species, R. oblongifolia, was described previously from Eocene Baltic and Bitterfeld amber, whereas the other species, R. tikhomirovae, is described here as new. Radula tikhomirovae differs from R. oblongifolia and two other Eocene species of that genus, R. sphaerocarpoides and R. baltica, by the presence of microphyllous branches and by the shape of its leaf lobules.
The prevalence and risk factors of lower back pain among healthcare workers in Iraq: A cross sectional study
Authors:   Baghdad Teaching Hospital, Baghdad, Iraq, Hazim Mahmood Al-Bakri Shaymaa , Al-Shuwaili Saeb Jasim ,   “Al-Hadi” University College, Baghdad, Iraq, Ataimish Haider Hekmat Jewaid ,   Imamein Kadhimein Medical City, Baghdad, Iraq
Published: April 2024

Background. Globally, the LBP prevalence among the general population varies from 15-45%. Work-related LBP is estimated to cause 818,000 disability-adjusted life years lost (DALYs) annually. Aim of study. To determine the prevalence and factors associated with LBP among Iraqi Healthcare workers. Methodology. This is a cross-sectional study that included 220 participants and was conducted at Baghdad during the period from 5/7/2023 to 25/11/2023. Lower back pain was assessed using an Arabic version of the Standardized Nordic Musculoskeletal Questionnaire (NMQ). Results. The life, annual, and weekly prevalence of LBP were 92.7%, 90.9%, and 58.2%, respectively. A statistically significant associated was detected between weekly prevalence of LBP and each of female gender, long working hours, BMI, and occupation. Conclusion. LBP is a highly prevalent condition among Iraqi HCWs and it caused considerable reduction to the quality of life and work performance. Risk factors for weekly prevalence were female gender, longer working hours, obesity, and working as a dentist.
Surgical outcomes of degenerative lumbar spondylolisthesis: A cohort study
Authors:   “Al Hussein” Teaching Hospital, Al-Muthanna, Sammawa, Iraq, Alabid Saif Saood Abdlrazaq , Faisel Abdulrahman Kamal ,   “Ibn Sina” Teaching Hospital, Erbil, Iraq, Abdulhameed Tarik Abdulwahid ,   Scientific Council of Spine Surgery Subspecialty, Arab Council of Health Specializations, Baghdad, Iraq
Published: April 2024

Background. DLS is defined as the slippage of one vertebra over the one below, in association with intervertebral disc degeneration and arthritis of the facet joints of the involved vertebrae, which will cause canal stenosis. Purpose. The primary objective of this study is to compare the outcome after surgical intervention (with neural decompression, fusion and fixation) in proved patients with lumbar degenerative spondylolisthesis (DLS). Patients and methods. Fifty patients with symptomatic DLS, in the period between October 2021 and March 2023, graded using Myerding scale, operated on by instrumented posterolateral fusion and decompression. Mean patients’ age at surgery was 50 years (range, 49–69). Surgical results were evaluated using ODI. Lumbar spine radiographs were used to evaluate the status of fixation constructs, the sagittal balance and the status of fusion. Results. Intraoperative and postoperative complications were encountered, but all were relatively not significant. Follow up time was 18 months. Clinical outcome was good or very good in 30 patients and satisfactory in 13 patients. This research showed that surgical intervention in patients with DLS is a valid option for addressing the clinical symptoms, surgical outcome, planned pain relief and return to daily activity. Conclusion. DLS is a common pathology, many treatment options are available including conservative and surgical, surgery is a valid option for candidates with DLS as it aims to decompress the neural tissue and correct sagittal balance.
The Role of Halal Certification and Brand Image in Increasing Consumer Trust (Case Study of MSMEs Crispy Masjef Bananas)
Authors: Muhnidin Arif , Br. Pinem Rasta Kurniawati
Published: April 2024

One of the MSME products in the city of Medan that has been certified halal is Pisang Crispy Masjef, founded in 2020 and quite well known among the people around Medan Johor for its crispy bananas and abundant toppings. The problem in this research is whether halal certification and brand image have an influence on increasing consumer trust and promoting Masjef Crispy Banana MSMEs, as well as what the owner's role is in increasing consumer trust. The objectives of this research are: (1) to know and analyze the effect of halal certification in increasing consumer confidence; (2) to explain and analyze the influence of brand image in promotion; and (3) to understand the role of the owner of Masjef Crispy Banana UMKM in increasing consumer trust through halal certification and brand image. The research method used in this study is descriptive quantitative. The research results show that halal certification and brand image have a significant effect on increasing consumer trust, with the t-count value of the halal certification variable being 4.963 and the t-count value of the brand image variable being 9.512, which is proven to be greater than the t-table value of 1.673. Furthermore, this research also indicates that the owner of the Crispy Masjef Banana UMKM plays a role in increasing consumer confidence by arranging halal certification and carrying out re-branding according to surveys and market demand, changing from "Bersama Pisang Horn Masjef" which uses the main ingredient of banana horns to "Crispy Banana Masjef" which uses the main ingredient of kepok banana.
Colección Instrumentos musicales José Ferrero
Authors: Gómez Rueda Andrés Alberto
Published: April 2024

La colección de instrumentos musicales de José Ferrero, depositada en el Instituto de Estudios Albacetenses “Don Juan Manuel”, representa un corpus muy heterogéneo en el que se reúnen piezas de diversas familias, géneros y estilos. La variedad de instrumentos y su valor musicológico realzan la importancia de la que es, a fecha actual, la colección más grande de este tipo que se encuentra en Albacete y que es posible visitar.
Brain Tumor Detection Through Advanced Computational Methods
Authors: Veera Krishna Maddinala Viswanath , Vishnu Charan Pemmaraju , Mounika B.C.S , Younus Md. Maseed
Published: April 2024

Brain tumors are abnormal growth of bulk mass in the brain which might harmful or harmless, posing a challenge for evaluation due to the protective skull covering, the cranium. The prior detection and diagnosis is very important and decide the survival of the patient, if not diagnosed and treated earlier the life time of the patient is exponentially decreased which makes Detecting and predicting brain tumors efficiently is crucial for timely intervention. Neuroradiology employs various methods such as biopsy, radioactive iodine testing, and MRI reports, with MRI being the most prevalent. However, interpreting MRI reports demands expertise and time, necessitating a more efficient approach. Hence, we propose leveraging machine learning and deep learning algorithms to develop a model for brain tumor detection such as Convolutional Neural Network (CNN) for image processing and ML algorithms which take the parameters of an MRI report and predict the type of tumor for prediction part. The system is time efficient and comes in handy for the medical practitioner to analyze the brain tumor in its early stages and treat it appropriately before the situation gets out of hand and increases the lifetime of the patient.
Predicting Coronary Heart Disease using Various Regression Analysis
Authors: Chavan Varun , Doaj Niyati , Vaswani Naveen
Published: April 2024

Nowadays, cardiovascular diseases are the major concern for Human beings. Cardiovascular Heart Diseases (CHDs) are the major reason for mortality globally causing millions of deaths each year. The global death toll from Cardiovascular Heart Disease (CHD) rose from 12.1 million in 1990 to 20.5 million in 2021. The age-standardized death rate for CHD in India was 282 deaths/100000 was higher compared with global levels that is 233 deaths/100000. The leading factors contributing to cardiovascular diseases or fatalities encompass high cholesterol level, triglyceride, etc. These are the most common factors nowadays which result in heart attack in humans. The main aim of this particular project is to explore various risk factors associated with myocardial infarction, commonly known as Heart Attack. We have used tensorflow and Keras frameworks for the following project. In this project, we utilize neural network models to forecast the risk of coronary heart disease (CHD) using various features. The prediction process involves training the models on a portion of the data and assessing their effectiveness on the remaining test set. These models are designed to discern patterns and correlations between input features and the target variable, 'chd'. The choice of features, architecture, and training parameters influences the model's predictive performance. The research focuses on two distinct neural network models: the first, 'sbp_model,' predicts CHD using only systolic blood pressure ('sbp'), while the second, 'linear_model,' utilizes all available features after normalization. Both models are evaluated on their ability to predict CHD through mean absolute error, with training histories and loss curves analysed. We have taken into consideration all the important Regression Models.
Spatial Distribution of Intracluster Light versus Dark Matter in Horizon Run 5
Authors: Yoo Jaewon , Park Changbom , Sabiu Cristiano G. , Singh Ankit , Ko Jongwan , Lee Jaehyun , Pichon Christophe , Jee M. James , Gibson Brad K. , Snaith Owain , Kim Juhan , Shin Jihye , Kim Yonghwi , Kim Hyowon
Published: April 2024

One intriguing approach for studying the dynamical evolution of galaxy clusters is to compare the spatial distributions among various components such as dark matter, member galaxies, gas, and intracluster light (ICL). Utilizing the recently introduced weighted overlap coefficient (WOC), we analyze the spatial distributions of components within 174 galaxy clusters (M
tot > 5 × 1013
M
⊙, z = 0.625) at varying dynamical states in the cosmological hydrodynamical simulation Horizon Run 5. We observe that the distributions of gas and the combination of ICL with the brightest cluster galaxy (BCG) closely resembles the dark matter distribution, particularly in more relaxed clusters, characterized by the half-mass epoch. The similarity in spatial distribution between dark matter and BCG+ICL mimics the changes in the dynamical state of clusters during a major merger. Notably, at redshifts >1, BCG+ICL traced dark matter more accurately than the gas. Additionally, we examined the one-dimensional radial profiles of each component, which show that the BCG+ICL is a sensitive component revealing the dynamical state of clusters. We propose a new method that can approximately recover the dark matter profile by scaling the BCG+ICL radial profile. Furthermore, we find a recipe for tracing dark matter in unrelaxed clusters by including the most massive satellite galaxies together with the BCG+ICL distribution. Combining the BCG+ICL and the gas distribution enhances the dark matter tracing ability. Our results imply that the BCG+ICL distribution is an effective tracer for the dark matter distribution, and the similarity of the spatial distribution may be a useful probe of the dynamical state of a cluster.
Investigation of Profile Shifting and Subpulse Movement in PSR J0344-0901 with FAST
Authors: Tedila H. M. , Yuen R. , Wang N. , Li D. , Wen Z. G. , Yan W. M. , Yuan J. P. , Han X. H. , Wang P. , Zhu W. W. , Dang S. J. , Wang S. Q. , Xie J. T. , Wu Q. D. , Khasanov Sh. ,   FAST Collaboration
Published: April 2024

We report two phenomena detected in PSR J0344−0901 from two observations conducted at frequencies centered at 1.25 GHz using the Five-hundred-meter Aperture Spherical Radio Telescope. The first phenomenon manifests as the pulse emission shifting to later longitudinal phases and then gradually returning to its original location. The event lasts for about 216 pulse periods, with an average shift of about 0.°7 measured at the peak of the integrated profile. Changes in the polarization position angle (PPA) are detected around the trailing edge of the profile, together with an increase in the profile width. The second phenomenon is characterized by the apparent movement of subpulses, which results in different subpulse track patterns across the profile window. For the first time in this pulsar, we identify four emission modes, each with unique subpulse movement, and determine the pattern periods for three of them. Pulse nulling was not detected. Modeling of the changes in the PPA using the rotating vector model gives an inclination angle of 75.°12 ± 3.°80 and an impact parameter of −3.°17 ± 5.°32 for this pulsar. We speculate that the subpulse movement may be related to the shifting of the pulse emission.
The Slipping Magnetic Reconnection and Damped Quasiperiodic Pulsations in a Circular Ribbon Flare
Authors: Huang Jing , Tan Baolin , Zhang Yin , Zhu Xiaoshuai , Yang Shangbin , Deng Yuanyong
Published: April 2024

The study of circular ribbon (CR) flares is important to understand the three-dimensional magnetic reconnection in the solar atmosphere. We investigate the slipping brightenings and damped quasiperiodic pulsations in a CR flare by multiwavelength observations. During the flaring process, two extreme ultraviolet brightenings (SP1 and SP2) slip synchronously along the ribbon in a counterclockwise direction. The ribbon and fans between them show synchronous enhancement with the microwave and hard X-ray (HXR) CR source. In the magnetohydrostatic extrapolation results and observations, the dome and outer spine display an evident counterclockwise twisting feature. We propose the slipping reconnection occurs between the fan and outer spine in the null point, which covers the region from SP1 to SP2. The fan of SP1 shows the strongest twist and produces the most efficient reconnection. The ribbon after SP1 becomes weak due to the destruction of the fan configuration. The fan of SP2 is in the front of the slipping motion, which initiates new reconnection and brightens the local ribbon. The twisting of the dome continuously promotes new reconnection in the null point, which brightens the ribbon in sequence to display a counterclockwise slipping feature. Thus, the twist of the dome may trigger and dominate the slipping reconnection, and the rotation of the central positive pole could be one possible cause of the twist. After the peak, the microwave and HXR emission shows damped oscillations at a period of 15 s. The collapse of the fan–spine structure may lead to the standing kink oscillations of the fan to modulate the reconnection and particle acceleration process.
Hidden Companions to Intermediate-mass Stars. XVII. Uncovering a 0.72 M
⊙, 0.35 au Companion in the Spectroscopic Binary Sigma Sculptoris*
Authors: Waisberg Idel , Klein Ygal , Katz Boaz
Published: April 2024

Sigma Sculptoris is a nearby star that was suspected of being a rotating Ap variable. It was recently found not to be an Ap star but rather a 47 days single-lined spectroscopic binary. Here we report on the direct detection of the companion with a K band flux ratio of 5.5% at a projected separation of 5.16 mas based on a VLTI/GRAVITY observation. We estimate isochrone masses M

A
 = 1.95M
⊙ and M

B
 = 0.72M
⊙, a semimajor axis a = 0.35 au and an orbital inclination i = 27° (or 153°). The large rotational velocity of the primary (assuming spin–orbit alignment) is consistent with the lack of prominent chemical peculiarities.
Three-dimensional Atmospheric Dynamics of Jupiter from Ground-based Doppler Imaging Spectroscopy in the Visible
Authors: Schmider Francois-Xavier , Gaulme Patrick , Morales-Juberías Raúl , Jackiewicz Jason , Gonçalves Ivan , Guillot Tristan , Simon Amy A. , Wong Michael H. , Underwood Thomas , Voelz David , Sanchez Cristo , DeColibus Riley , Kovac Sarah A. , Sellers Sean , Gilliam Doug , Boumier Patrick , Appourchaux Thierry , Dejonghe Julien , Rivet Jean Pierre , Markham Steve , Howard Saburo , Abe Lyu , Mekarnia Djamel , Ikoma Masahiro , Hanayama Hidekazu , Sato Bun’ei , Kunitomo Masanobu , Izumiura Hideyuki
Published: April 2024

We present three-dimensional (3D) maps of Jupiter’s atmospheric circulation at cloud-top level from Doppler-imaging data obtained in the visible domain with JIVE, the second node of the JOVIAL network, which is mounted on the Dunn Solar Telescope at Sunspot, New Mexico. We report on 12 nights of observations between 2018 May 4 and May 30, representing a total of about 80 hr. First, the average zonal wind profile derived from our data is compatible with that derived from cloud-tracking measurements performed on Hubble Space Telescope images obtained in 2018 April from the Outer Planet Atmospheres Legacy program. Second, we present the first ever 2D maps of Jupiter’s atmospheric circulation from Doppler measurements. The zonal velocity map highlights well-known atmospheric features, such as the equatorial hot spots and the Great Red Spot (GRS). In addition to zonal winds, we derive meridional and vertical velocity fields from the Doppler data. The motions attributed to vertical flows are mainly located at the boundary between the equatorial belts and tropical zones, which could indicate active motion in theses regions. Qualitatively, these results compare well to recent Juno data that have unveiled the 3D structure of Jupiter’s wind field. To the contrary, the motions attributed to meridional circulation are very different from what is obtained by cloud tracking, except at the GRS. Because of limitations with data resolution and processing techniques, we acknowledge that our measurements of the vertical or meridional flows of Jupiter are still to be confirmed.
Expression of norA, norB and norC efflux pump genes mediating fluoroquinolones resistance in MRSA isolates
Authors: Hamady Asmaa B , Abd El-Fadeal Noha M , Imbaby Samar , Nassar Hassnaa MA , Sakr Mohamed Gamal , Marei Yara E
Published: April 2024

Introduction: Although fluoroquinolones are used to treat methicillin-resistant Staphylococcus aureus (MRSA)-induced infections, acquisition of antibiotic resistance by bacteria has impaired their clinical relevance. We aimed to evaluate the frequency of norA, norB, and norC efflux pump genes-mediating fluoroquinolones resistance and measure their expression levels in MRSA isolates.
Methodology: 126 S. aureus isolates were collected from different clinical samples of adult hospitalized patients and identified by conventional microbiological methods. MRSA was diagnosed by cefoxitin disc diffusion method and minimum inhibitory concentration (MIC) of ciprofloxacin by broth microdilution method. The expression levels of efflux pump genes were measured by quantitative real-time polymerase chain reaction (qRT-PCR).
Results: 80 (63.5%) MRSA isolates were identified and showed high level of resistance to erythromycin (80%), gentamicin (75%), clindamycin (65%) and ciprofloxacin (60 %). norA, norB and norC were detected in 75%, 35% and 55% of the MRSA isolates respectively. norC was the most commonly overexpressed gene measured by qRT-PCR, occurring in 40% of MRSA isolates, followed by norA (35%) and norB (30%). The expression of these genes was significantly higher in ciprofloxacin-resistant than quantitative real-time PCR ciprofloxacin-sensitive MRSA isolates.
Conclusions: This study showed high prevalence and overexpression of efflux pump genes among MRSA isolates which indicates the significant role of these genes in the development of multidrug resistance against antibiotics including fluoroquinolones.
Efficacy of Linezolid in the management of pneumonic COVID-19 patients. Bioinformatics-based clinical study
Authors: Eid Ragaey A , Elgendy Marwa O , Sayed Ahmed M , Abdallah Abdelrahman M , Mostafa Hayam MA , Mohammed M Elsisi Ahmed , Hamed Ahmed M , Shaker Marwa Abdallah
Published: April 2024

Introduction: At the beginning in July 2023, there has been a significant increase in daily hospital admissions attributed to the new variant of COVID-19. Aim of this study is to explore the clinical benefits and outcomes of using linezolid in the management of pneumonic COVID-19 patients.
Methodology: The study included 230 patients with SARS-CoV-2 infection confirmed by RT-PCR. Group 1: 118 patients were managed with Linazolid alongside steroids. Group 2: (control group) patients treated according to the Protocol for Egyptian COVID-19 management outlines and WHO guidelines (112 patients). Each patient group was categorized into 3 age groups: 20-40 years, 41-65 years, and over 65 years. Patients were carefully followed up until recovery or mortality. A docking analysis was carried out to investigate the potential of linezolid to act as an Mpro inhibitor.
Results: Group 1's average recovery time was 15.1 days in contrast to 18.7 days for Group 2 (control). There were no deaths reported. In silico investigations revealed that Linezolid was able to achieve a binding mode comparable to that of the co-crystalized inhibitor.
Conclusions: Linazolid is considered an effective antiviral weapon against SARS-COV-2. It could be used in the management plan of pneumonic individuals due to SARS-COV-2 infection. We recommend using it to combat the current wave caused by Omicron EG-5 Variant.
Le droit international humanitaire face aux défis du XX e siècle
Authors: Meyer Antoine
Published: April 2024

Cette présentation s’attache aux développements récents et aux perspectives en matière de protection de l’enfance dans les conflits armés, avec un éclairage particulier sur la question des enfants associés aux forces et aux groupes armés. Elle vise un bref exposé des enjeux de protection et du cadre normatif de référence liant droit international humanitaire et droit international des droits de l’Homme (I); une mise en perspective des leviers juridiques et politiques de mise en œuvre de ces normes et de réponse à l’« impératif humanitaire » reconnu dans l’engagement du Conseil de Sécurité des Nations unies (II). Elle dégage enfin quelques priorités pour la protection des enfants associés aux forces et aux groupes armés, dans une approche globale fondée sur les droits de l’enfant (III) .
Local linear estimation for the censored functional regression
Authors: Almulhim Fatimah A , Merouan Torkia , Alamari Mohammed B. , Mechab Boubaker
Published: April 2024

This work considers the Local Linear Estimation (LLE) of the conditional functional mean. This regression model is used when the independent variable is functional, and the dependent one is a censored scalar variable. Under standard postulates, we establish the asymptotic distribution of the LLE by proving its asymptotic normality. The obtained results show the superiority of the LLE approach over the functional local constant one. The feasibility of the studied model is demonstrated using artificial data. Finally, the usefulness of the obtained asymptotic distribution in incomplete functional data is highlighted through a real data application.
On Decolonization and its Correlates
Authors: Filho Wilson Trajano
Published: April 2024

This essay offers a critical analysis of the literature on decolonization (and its correlates), from the studies carried out by colonial agents and administrators to the recent vogue for postcolonial and decolonial studies. It highlights the limitations of the top-down approach of most studies up to the 1970s, the binarism that has characterized contemporary studies, and the conceptual ambivalence as well as marketing perspective that distinguish the decolonial approach. Lastly, it considers the idea of using the conceptual framework of creolization studies and the ideas of Oswald de Andrade on anthropophagy to get a better understanding of decolonization.
Sonja K. Foss : La rhétorique invitationnelle comme défi féministe à la tradition rhétorique
Authors: Foss Sonja K. , Shugart Helene A.
Published: April 2024

Dans cet essai, Sonja K. Foss est interviewée par Helene A. Shugart sur la rhétorique invitationnelle, une forme de rhétorique ancrée dans les principes féministes qui remet en question la tradition rhétorique classique axée sur la persuasion. Elle décrit les événements clés qui l’ont amenée à s’intéresser à la fois à la rhétorique et au féminisme, et présente les contextes féministes et rhétoriques dans lesquels sa théorie s’est développée. Elle en explique les principes et les hypothèses-clés et parle de sa réception dans la discipline de la communication, tout en offrant quelques applications de la théorie dans le monde réel. Elle donne un autre exemple de projet dans lequel elle intègre féminisme et rhétorique - sa théorisation de deux paradigmes de changement - et conclut en suggérant comment elle applique dans sa propre vie certains des principaux concepts qui ont émergé de cette intégration du féminisme et de la rhétorique.
Sonja K. Foss: Invitational Rhetoric as a Feminist Challenge to the Rhetorical Tradition
Authors: Foss Sonja K. , Shugart Helene A.
Published: April 2024

In this essay, Sonja K. Foss is interviewed by Helene A. Shugart about invitational rhetoric, a form of rhetoric rooted in feminist principles that challenges the classical rhetorical tradition’s focus on persuasion. She begins by describing key events that led to her interest in both rhetoric and feminism and notes the feminist and rhetorical contexts in which invitational rhetoric developed. She explains the key tenets and assumptions of invitational rhetoric and its reception in the communication discipline and provides some real world applications of the theory. She offers another example of a project in which she integrates feminism and rhetoric – her theorizing of two paradigms of change – and concludes by suggesting how she applies in her own life some of the major concepts that emerged from her integration of feminism and rhetoric.
Étude de la conflictualité : les apports des Prolégomènes à une sémantique des conflits sociaux d’Alfredo Lescano
Authors: Genty Noémie
Published: April 2024

Cette « réflexion critique » examine les apports du livre d’Alfredo Lescano Prolégomènes à une sémantique des conflits sociaux à l’étude de la conflictualité sociale. Pour cerner les particularités de cette théorie, nous présentons l’ensemble du système élaboré ainsi que les soubassements épistémologiques sur lesquels ce dernier repose et comparons cette proposition avec des études de la polémique qui font autorité en Argumentation, Rhétorique et Analyse de Discours : entre autres, Sémantique de la polémique de Maingueneau, Apologie de la polémique d’Amossy ou Dialogue de Sourds d’Angenot. Ce faisant, il apparaît qu'est proposée une théorie inédite dans laquelle l’espace sémantique d’un conflit est considéré comme le lieu où sont rendues (in)disponibles des actions discursives ou non discursives.
Michael A. Gilbert : Ne pas argumenter logiquement n’est pas illogique : il y a d’autres façons de communiquer des arguments
Authors: Gilbert Michael A. , Carozza Linda
Published: April 2024

Michael A. Gilbert a apporté une contribution significative à la théorie contemporaine de l’argumentation. Ses apports les plus remarquables résident dans sa théorie multimodale de l’argumentation et dans sa théorie de l’argumentation dite « coalescente », des modèles novateurs qu’il a développés pour étudier la façon dont les interlocuteurs discutent réellement dans la vie courante. Ses idées n’ont pas toujours été comprises, appréciées ou reconnues par l’ensemble de la communauté des spécialistes d’argumentation. Néanmoins, récemment, le Centre for Research in Reasoning, Argumentation and Rhetoric (en Ontario, au Canada) a reconnu l’importance de sa contribution en organisant un institut d’une semaine entière consacré à ses travaux. Aussi provocantes que puissent paraître ses théories, les spécialistes de la rhétorique n’en peuvent pas moins trouver un certain terrain d’entente avec ses travaux.