bluuebunny/crossref_metadata_2025 huggingface dataset:
COVID-19 Outcomes by Cancer Status, Site, Treatment, and Vaccination
Authors: Salvatore Maxwell , Hu Miriam M. , Beesley Lauren J. , Mondul Alison M. , Pearce Celeste Leigh , Friese Christopher R. , Fritsche Lars G. , Mukherjee Bhramar
Published: January 2023

Background:

Studies have shown an increased risk of severe SARS-CoV-2–related (COVID-19) disease outcome and mortality for patients with cancer, but it is not well understood whether associations vary by cancer site, cancer treatment, and vaccination status.

Methods:

Using electronic health record data from an academic medical center, we identified a retrospective cohort of 260,757 individuals tested for or diagnosed with COVID-19 from March 10, 2020, to August 1, 2022. Of these, 52,019 tested positive for COVID-19 of whom 13,752 had a cancer diagnosis. We conducted Firth-corrected logistic regression to assess the association between cancer status, site, treatment, vaccination, and four COVID-19 outcomes: hospitalization, intensive care unit admission, mortality, and a composite “severe COVID” outcome.

Results:

Cancer diagnosis was significantly associated with higher rates of severe COVID, hospitalization, and mortality. These associations were driven by patients whose most recent initial cancer diagnosis was within the past 3 years. Chemotherapy receipt, colorectal cancer, hematologic malignancies, kidney cancer, and lung cancer were significantly associated with higher rates of worse COVID-19 outcomes. Vaccinations were significantly associated with lower rates of worse COVID-19 outcomes regardless of cancer status.

Conclusions:

Patients with colorectal cancer, hematologic malignancies, kidney cancer, or lung cancer or who receive chemotherapy for treatment should be cautious because of their increased risk of worse COVID-19 outcomes, even after vaccination.

Impact:

Additional COVID-19 precautions are warranted for people with certain cancer types and treatments. Significant benefit from vaccination is noted for both cancer and cancer-free patients.
Identificando la condición límite para la problematización del juvenicidio (Apuntes generales para la construcción de la categoría aplicada al contexto salvadoreño 2003 – 2022)
Authors:   Centro de Estudios e Investigaciones sobre la Persona Joven (Ceijuve), El Salvador, Majano Moisés
Published: January 2023

El juvenicidio es una categoría inédita para el contexto salvadoreño, lo que permite partir del análisis de la aplicación categorial en otros contextos similares a este. Esta categoría inexplorada, permitirá la comprensión del proceso histórico salvadoreño de las últimas dos décadas desde una perspectiva generacional con una aplicación del enfoque de juventudes que no se limita al desarrollismo económico como generalmente se mal entiende. El juvenicidio como fenómeno en El Salvador puede ser complejo si se analiza desde las masacres en masas de determinados grupos de juventudes, ya que el mismo proceso histórico, permite la opacidad analítica. La revisión de narrativas, cifras y opiniones en los diferentes períodos en los que se divide el análisis, es fundamental para ir tejiendo el análisis desde la perspectiva de juvenicidio, reuniendo todos aquellos elementos que ya fueron identificados por otras investigadoras, pero que dispersos, no logran poner de manifiesto la problemática a la que se han enfrentado las juventudes salvadoreñas desde 2003
“Não é só um comprimido!”: conflitos, moralidades e a gestão de um “saber” sobre viver com HIV/Aids indetectável
Authors: Coitinho Filho Ricardo Andrade
Published: January 2023

Este artigo busca examinar as tensões, conflitos e ajustamentos que têm sido mobilizados a partir da emergência da indetectabilidade viral para o HIV/Aids, enquanto política global de saúde. A análise parte das diferenças geracionais que, ao serem associadas a outros marcadores sociais, modulam formas de sentir, perceber e vivenciar as experiências cotidianas com HIV/Aids indetectável e, mediante a isso, implicam na produção de enquadramentos políticos. Portanto, se insere num cenário recente de disputas entre gerações do ativismo e que complexifica a centralidade biomédica que ainda permeia a condução da política de Aids. São tomadas como foco de reflexão duas situações etnográficas que fazem parte de um campo mais amplo da pesquisa desenvolvida entre 2016 e 2021 junto à Rede de Jovens + RJ.
Escolarização e reivindicação de uma teoria do conhecimento guarani e kaiowá: interconexões entre o modo de ser indígena - ava reko - e o modo de ser não indígena - karai reko
Authors: Lourenço Renata , Pereira Levi Marques
Published: January 2023

O artigo discute o engajamento de intelectuais Kaiowá e Guarani no esforço de sistematização de uma teoria do conhecimento oriunda de seus próprios princípios cosmológicos. Tal teoria seria forjada nas conexões multifacetadas entre o sistema de conhecimento indígena - ava reko -, referido como distintas modalidades de seres, habitantes dos vários planos de existência e acessados por especialistas indígenas, como os homens e mulheres xamãs, e o sistema não indígena de escolarização, no qual os jovens letrados estão intensamente inseridos - karai reko. O objetivo é demonstrar como o processo de letramento ou escolarização, que à primeira vista afastaria ou aprisionaria a perspectiva indígena, muitas vezes tem um efeito contrário, provocando a intensificação da (re)conexão desses/as jovens letrados/as com sua própria tradição. Priorizamos o diálogo com esses/as jovens pesquisadores/as e com suas produções escritas como base para o desenvolvimento da hipótese aqui sugerida.
Uma adaptação à brasileira: Uma análise comparativa entre João e Maria, dos irmãos Grimm, e a versão do programa Conta Pra Mim
Authors: Nascimento Antonio Augusto Castro do
Published: January 2023

Este artigo traça uma análise comparativa entre o conto de fadas João e Maria, escrito pelos irmãos Grimm, e a disponibilizada pelo programa Conta Pra Mim, do Ministério da Educação (MEC), cuja coleção de livros veio a público em 2020. A partir de teorias sobre o conto de fadas (Volobuef, 1993 e 2011; Coelho, 2003; Zipes, 2012) e sobre adaptações (Hutcheon, 2013), pretende-se tensionar as ausências e alterações feitas pela versão brasileira e refletir acerca da problemática que isso representa para a literatura infantil.
A racionalidade neoliberal nas contratações públicas de combate à sindemia da Covid-19
Authors: Rufino Filho Ednaldo Tavares , Vettorato Poala
Published: January 2023

A crise sanitária decorrente da Covid-19 constitui uma sindemia devido à interação dos aspectos biológicos com as precárias condições sociais. Para este estudo, examinaram-se as aquisições públicas relacionadas ao enfrentamento dessa sindemia, contemplando o Rio Grande do Sul e Porto Alegre. Trata-se de um estudo exploratório e qualitativo, sendo aanálise realizada após o levantamento bibliográfi co sobre micropolítica e neoliberalismo. A coleta de dados foi realizada no painel gerencial de contratações relacionadas à Covid-19 da Controladoria Geral da União (LicitaCon) do Tribunal de Contas do Rio Grande do Sul, para as compras do estado e do município de Porto Alegre. Notou-se que a maior licitação da Central de Licitações do estado foi de equipamentos de informática e, no município, de cestas básicas. Ao analisar as compras governamentais dos entes municipal e estadual, verificou-se que foram permeadas pela racionalidade neoliberal.
A forma do porvir: literatura vitoriana, a máquina, as classes ou sobre a ficção científica de H. G. Wells en fin de siècle e um estudo sobre The time machine
Authors: Berchez Amanda Naves
Published: January 2023

O principal objetivo deste artigo é demostrar como o romance vitoriano The time machine de H. G. Wells reverbera, pelas óticas da ficção científica e distópica, questões (de ordem, sobretudo, social) intensamente exploradas no gênero romanesco industrial, também nomeado condition-of-England novels, ao exemplo das lutas de classes e da desumanização para com o proletariado no nicho industrial. Para tanto, recuperamos tanto histórica quanto teoricamente todos os referidos gêneros e formas literários.
The film 'Hollow city' - an adaptation of the book 'The adventures of Ngunga': from utopia to dystopia
Authors: Lauriti Thiago
Published: January 2023

This article seeks to identify the “new lenses and discourses” that mark the film Hollow city, from 2004, by the Angolan filmmaker Maria João Ganga, in relation to the text that serves as a source for Ngunga’s adventures, by 1972, by fellow Angolan artist Artur Carlos Maurício Pestana dos Santos, known as Pepetela. For this purpose, studies by Robert Stam (2006) and Linda Hutcheon (2011) on adaptation will be used as theoretical and analytical contributions. Both explore the intertextual or dialogical possibilities that are established when a literary work is adapted for the cinema, transporting local particularities to other space-times that result in a new, hybrid work and not necessarily inferior to the one that gave rise to it. Both move away from the rhetoric of loss that laments what was lost in the transition from novel to film.
Pensadores do nada: Heidegger e a mística judaica medieval
Authors: Ciucu Cristina , Gonçalves Lucas de Lima Cavalcanti
Published: January 2023

Tradução de: Ciucu, C. (2010). Les penseurs du néant: Heidegger et la mystique juive du Moyen Âge. Yod, 5, 215-233, por Lucas de Lima Cavalcanti 
DOI: https://doi.org/10.4000/YOD.676
Nenhum arquivo te reconstituirá
Authors: Moraes Joana Passi de
Published: January 2023

Tradução dos capítulos 1 e 2 do livro No archive will restore you de Julietta Singh.
Os arquivos de Marguerite Duras: a intermidialidade no processo criativo
Authors: Oliveira Luciene Guimarães de
Published: January 2023

Os arquivos de Marguerite Duras, preservados no IMEC (Institut Mémoires de l’édition contemporaine), permitem desvelar vários aspectos da obra da escritora, cineasta e dramaturga, confirmando um processo criativo de natureza intermidial, pois a obra transita entre o texto literário, a peça de teatro e o filme. Explorando esse campo transdisciplinar — a intermidialidade —, percebe-se como a obra se manifesta na fronteira tênue entre a literatura e o cinema.
Improving College Choice in Centralized Admissions: Experimental Evidence on the Importance of Precise Predictions
Authors: Ye Xiaoyang
Published: January 2023

This paper provides the first experimental evidence of how admission outcomes in centralized systems depend on strategic college choice behaviors. Centralized college admissions simplify the application process and reduce students' informational barriers. However, such systems also reward informed and strategic college choices. In particular, centralized admissions can be difficult to navigate because they require students to understand how application portfolios and placement priorities map to admission probabilities. Using administrative data from one of the poorest provinces in China, I document that students made undermatched college choices that correlated with inaccurate predictions of admission probabilities. I then implemented a large-scale randomized experiment (N= 32,834) to provide treated students with either (a) an application guidebook or (b) a guidebook plus a school workshop. Results suggest that informing students on choosing colleges and majors based on precise predictions of admission probabilities can effectively improve student–college academic match by 0.1 to 0.2 standard deviation among compliers without substantially changing their college-major preferences.
‘Stretch’ and ‘Translate’: Gramscian Lineages, Fanonist Convergences in the (Post)Colony
Authors: Kipfer Stefan A. , Mallick Ayyaz
Published: January 2023

This paper establishes a theoretical linkage between Antonio Gramsci and Frantz Fanon. Gramsci’s critical-historicist method and its relationship to humanism, his integral understanding of Marxism, and emphasis on the moment of political practice resonate with Fanon’s articulation of the subjective and political-economic aspects of the colonial question, his activistic materialism, and his dialectically humanist universalism forged through anti-colonial struggle. Establishing this linkage presupposes engaging distinct currents of postcolonial Gramscianism in relation to each other and to the philological turn in Gramsci scholarship. In turn, a Gramsci–Fanon convergence helps elucidate the specificities of (post-)colonial contexts without elevating these into a civilisational-ontological difference. Emphasising their geographical sensitivity as a meeting point, pushing Gramsci towards Fanon helps us treat the global South and imperial heartlands relationally, in historico-geographical and specifically political terms. A Fanonian Gramsci (or Gramscian Fanon) thus allows us to tackle Eurocentrism without closing doors to a counter- or postcolonial Marxism.
Two new Phyllachora species in Southwest China
Authors: LI JIN-CHEN , WU HAI-XIA , SONG JIA-YU
Published: January 2023

Phyllachora species are biotrophic, obligate plant parasitic fungi featuring a high degree of host specificity, a high degree of species richness, and worldwide distribution. In this study, two Phyllachora species were collected from different hosts in Yunnan province, China. Based on morphological characteristics and multigene (LSU, ITS, SSU) phylogenetic analyses, they are introduced as two new taxa. Photographs, detailed descriptions, and notes are provided.
Endemism among Lord Howe Island Thysanoptera, with new species of Baenothrips (Phlaeothripidae) and Scirtothrips (Thripidae)
Authors: MOUND LAURENCE A. , WELLS ALICE
Published: January 2023

The Thysanoptera diversity of Lord Howe Island comprises 39 known species, of which 13 are considered likely to be endemic to this tiny remnant of an ancient submarine volcano. Three new species are described in Baenothrips, a small but widespread genus of wingless, fungus-feeding species in the Old World tropics. Two new species of Scirtothrips are described that are members of a species-group breeding on the youngest fronds of tree ferns.
Climate Change Effects on Irrigated Corn Growth in the Lower Mississippi Delta
Authors: Kannan Narayanan , Anapalli Saseendran
Published: January 2023

In this study, the possible climate change impacts on irrigated corn production in the lower Mississippi delta (LMD) region were analyzed. The observed daily maximum and minimum air temperature, wind speed, relative humidity (RH), and precipitation from 1960 to 2018 were used in the analysis. The length of the growing season, evapotranspiration (ET), and crop yield estimates from the precalibrated Root Zone Water Quality Model (RZWQM) were also used. Trend analyses were performed on growing-season averages for temperature, RH, and wind speed; growing-season totals for precipitation and ET; daily values of minimum and maximum temperature; and averages of RH and wind speed at critical corn growth stages. The last day of spring freezing (LDSF) and days with an average daily air temperature Ta of more than 35°C during corn silking were also included in the analysis. The trend analysis was performed using the modified Mann–Kendall test, Pettitt test, and Sen’s slope at a significance level of p ≤ 0.05. The results from our study pointed out increases in minimum Ta, increases in the number of days with Ta exceeding 35°C during the corn silking stage, increases in RH and decreases in ET, advancement of the LDSF by 2 weeks, and 8% reductions in corn yield that could be attributed to changes in climate. If the observed trends in climate (climate variability and change) and yield reductions continue in the region, it could be challenging to grow the corn crop in the LMD profitably.

Significance Statement

In recent years, growing corn and soybeans instead of cotton has been gaining popularity in the lower Mississippi delta (LMD) region. Our study is aimed to understand how climate change in the recent past (1960–2018) has affected irrigated corn production in LMD. This will help us to better understand the expected consequences of the future climate. We used observations of daily weather data from 1960 to 2018 and corn yield, water balance, and crop yield results from a computer model designed to simulate corn production. Tools were used to analyze trends and patterns in the data and results. Our analysis pointed out significant changes in weather, water balance, and yield decline for irrigated corn in the LMD.
A Multi-Temporal-Scale Modulation Mechanism for the Postprocessing of Precipitation Ensemble Forecasts: Benefits for Streamflow Forecasting
Authors: Bellier Joseph , Whitin Brett , Scheuerer Michael , Brown James , Hamill Thomas M.
Published: January 2023

In the postprocessing of ensemble forecasts of weather variables, it is standard practice to first calibrate the forecasts in a univariate setting, before reconstructing multivariate ensembles that have a correct covariability in space, time, and across variables, via so-called “reordering” methods. Within this framework though, postprocessors cannot fully extract the skill of the raw forecast that may exist at larger scales. A multi-temporal-scale modulation mechanism for precipitation is here presented, which aims at improving the forecasts over different accumulation periods, and which can be coupled with any univariate calibration and multivariate reordering techniques. The idea, originally known under the term “canonical events,” has been implemented for more than a decade in the Meteorological Ensemble Forecast Processor (MEFP), a component of the U.S. National Weather Service’s (NWS) Hydrologic Ensemble Forecast Service (HEFS), although users were left with material in the gray literature. This paper proposes a formal description of the mechanism and studies its intrinsic connection with the multivariate reordering process. The verification of modulated and unmodulated forecasts, when coupled with two popular methods for reordering, the Schaake shuffle and ensemble copula coupling (ECC), is performed on 11 Californian basins, on both precipitation and streamflow. Results demonstrate the clear benefit of the multi-temporal-scale modulation, in particular on multiday total streamflow. However, the relative gain depends on the method used for reordering, with more benefits expected when this latter method is not able to reconstruct an adequate temporal structure on the calibrated precipitation forecasts.
Revisiting the Do-Live-Well Health Promotion Framework: A Citation Content Analysis
Authors: Hamilton Kennedy A. , Letts Lori J. , Larivière Nadine , Moll Sandra E.
Published: January 2023

Background. The Do-Live-Well (DLW) framework was first published in 2015 and aimed to fill a theoretical gap in the health promotion literature related to the links between occupational patterns and health. However, the extent of uptake and use of the framework since publication is unknown. Purpose. To explore and reflect on the adoption and application of DLW in the literature. Method. Citation content analysis of two seminal DLW publications was conducted from 2015 to November 2022 across six databases. Findings. Seventeen citations directly applied DLW to inform research ( n = 10), practice ( n = 5) and knowledge translation ( n = 2). Implications. The findings highlight uptake of the framework in a range of settings, and how it can inform an occupation-based understanding of health and well-being. Ongoing knowledge dissemination, development of practice tools, and research to update evidence and examine relevance are needed to further advance the utility and application of the framework.
Fiber reinforced polypropylene composites interfacial behavior improvement fabricated by cold plasma jet SiOx nanoparticles deposition
Authors: Zhang Lin , Xia Zhangchuan , He Yadong , Xin Chunling , Yu Yang , Ren Feng , Wang Ruixue
Published: January 2023

In this study, cold atmospheric pressure plasma jet was adopted to glass fibers surface modification with tetraethyl orthosilicate as a precursor. To enhance the interfacial bonding forces of glass fiber reinforced polypropylene (GFRP) composites, SiOx nanoparticles were polymerized on the fiber surfaces. The effect of two factors (the distance between nozzle and fiber (D) and the treatment time (T)) on the interfacial bonding behavior of GFRP composites was studied. The modified fibers and composites properties, including surface topography, chemical composition, wettability and interfacial mechanical properties, were studied comprehensively. The optimal parameters were obtained at D = 17 mm and T = 12 s. Our results indicated that the interlaminar shear strength of GFRP composites was increased by 30.79% compared to control group. Further studies found that plasma treatment introduced larger surface roughness, surface energy and more oxygen-containing functional groups, which was responsible for the interlaminar shear strength improvement.
The Multiple Meanings of Discrimination
Authors: Harnois Catherine E.
Published: January 2023

Discrimination is one of the most important concepts for understanding, analyzing, and addressing social inequality. It is a term with many meanings, however, and existing research tells us little about how people understand and use the term. This study analyzes data from interviews with 38 English-speaking adults in the southeastern United States to examine how people use and make sense of the term discrimination. In structured interviews, participants described their experiences of mistreatment, reflected on whether their experiences were instances of discrimination, and explained their reasoning. Many participants expressed uncertainty about the meaning of discrimination and were unsure if it applied to particular situations. When asked to explain why they thought particular situations were or were not instances of discrimination, some participants relied on a legalistic framework, drawing from knowledge they had gained in their formal educational and training. Others foregrounded issues of inequality and social justice, explicitly invoking racism, sexism, and social class when explaining why something was or was not discrimination. A third group of participants, disproportionately but not exclusively White and non-Latinx, considered discrimination to be synonymous with “differential treatment” and unrelated to social inequality. Analyses suggest that these interpretive frameworks reflect participants’ legal consciousness, political consciousness, and their ability to read particular situations as connected to specific systems of inequality—that is, their literacies of particular inequalities.
The Revised Parent-Adolescent Conflict Issues Checklist: Development, Reliability, and Validity
Authors: Mokhtarnia Iraj , Zadeh Mohammadi Ali , Panaghi Leili , Cheraghi Mona
Published: January 2023

The present study developed the revised version of the Parent-Adolescent Conflict Issues Checklist (PACIC) by completing the judgment stage of systemic content validity. In the first study, to examine the necessity and relevance of each item, 40 experts were selected through a purposeful method. After the judgment stage, 92 items were reduced to 47 items and 13 factors. In the second study, to assess the confirmatory factor analysis, adolescent girls and boys aged 12–18 years completed the checklist ( N = 1350, mean age 15.4 years, girls 50.1%); also, the Youth Self-Report Scale (YSR), Adolescents' Perceived Family Collective Efficacy Scale (EFCP/A), and the Conflict Behavior Questionnaire (CBQ) were applied to assess concurrent validity, and to establish convergent validity, respectively. The obtained results supported the reconstructed model, and the items went well with the specified factors. The study achieved concurrent and convergent validity. The Cronbach’s alpha coefficients between 0.78 and 0.86 showed that this instrument has excellent internal consistency; moreover, PACIC-R has measurement invariance across gender; thus, PACIC-R can be applied to assess the issues of parent-adolescent conflict and the challenges of families as well.
Institutional pressures and RegTech challenges for banking: The case of money laundering and terrorist financing in Lebanon
Authors: Bakhos Douaihy Houanyda , Rowe Frantz
Published: January 2023

As banks face heightened levels of regulatory challenges, many of them, especially those in developing countries, are struggling to maintain their reputations. This paper addresses the following questions: How do commercial banks in developing countries like Lebanon respond to institutional pressures for compliance concerning anti-money laundering (AML) and counter-financing of terrorism (CFT)? How do Regulatory Technology (RegTech) solutions contribute to solving their compliance problems in this domain and why may the potential of RegTech be limited in the Lebanese context? To answer these questions, we conducted a field study among Lebanese commercial banks and their vendors. Based on thematic analysis, findings reveal the importance of technology for enhancing compliance of Lebanese banks with international regulations, especially US ones, thereby avoiding sanctions. Thus, the adoption of RegTech is mainly due to coercive pressures, whereas the choice of RegTech solutions is highly dependent on mimetic and normative forces, and happens later. Results also show that manual processes are insufficient for compliance due to the huge number of regulations and transactions. Hence, RegTech for AML/CFT is notably adopted for the efficient screening of clients and monitoring of their transactions. These solutions enhance decision-making processes for compliance teams, which become effective when the banks ensure an adequate interaction between employees and the new technologies. However, RegTech presents several additional challenges that have to be overcome for effective compliance such as finding the right vendors and ensuring data quality. Moreover, the geopolitical context in developing countries like Lebanon limits the potential of RegTech for AML/CFT.
Epidermoid cyst in atypical intracranial areas transformed to epidermoid carcinoma: a case report
Authors: Zhang Xiaoli , Zhan Ao , He Deping , Wei Zhenghong , Pan Yawen , Li Xinlong
Published: January 2023

Intracranial epidermoid cysts, also known as epidermal cysts, grow slowly and may be occult. When small, epidermoid cysts are usually clinically unremarkable or cause no definitive symptoms. At typical sites, they are easily found through magnetic resonance imaging, which aids evaluation before surgery. However, in rare cases, epidermoid cysts are situated in unusual locations or transformed to malignancy, and preoperative misdiagnosis is possible. Here, the case of a 58-year-old male patient who presented with weakness in the left lower limb and was diagnosed with a malignant epidermoid cyst in the right frontoparietal lobe, right lateral ventricle, is reported. Surgery was performed to remove the tumour followed by radiotherapy, and the patient was reported to be living independently after approximately 11 months of follow-up.
Huge sialolith of the submandibular gland: a case report and review of literature
Authors: Ashindoitiang John Adi , Nwagbara Victor Ikechukwu Canice , Ugbem Theophilus , Odoks Rachel Kanong , Udo Solomon Akpan , Akpan Samuel Okokon , Ogamba Nzubechukwu , Asuquo Maurice Efana
Published: January 2023

The formation of stone in the ductal system of the salivary gland is termed sialolithiasis, with the submandibular gland being the most commonly affected. The precise aetiology is unknown but certain factors peculiar to the submandibular gland accounts for its likelihood of developing a calculous disease. Stones are classified based on their dimension, and may be silent or present with symptoms attributable to the size, location and complications. Here, a 50-year-old female who presented with a painless swelling in the left submandibular region that had grown slowly over the previous year, is reported. Following clinical and radiologic evaluation, left submandibular stone disease was preoperatively diagnosed. The patient underwent sialoadenectomy with transient palsy of the marginal mandibular branch of the facial nerve. Histopathology confirmed sialolith (2.7 cm) with severe squamous metaplasia of the duct. This presentation demonstrates some peculiar features attributable to the size, vertical orientation and location of the stone, in addition to the compression of the gland, thick fibrous capsule and significant squamous metaplasia of the duct. These findings require further evaluation for optimal treatment in view of the emerging trends for managing sialolithiasis.
Accuracy of Magnetic Resonance Imaging in the Diagnosis of Multiple Ligament Knee Injuries: A Multicenter Study of 178 Patients
Authors: Sanchez-Munoz Enrique , Lozano Hernanz Beatriz , Zijl Jacco A.C. , Passarelli Tirico Luís Eduardo , Angelini Fabio Janson , Verdonk Peter C.M. , Vuylsteke Kristien , Andrade Renato , Espregueira-Mendes João , Valente Cristina , Figueroa Francisco , Figueroa David , Maestro Fernández Antonio
Published: January 2023

Background:

Magnetic resonance imaging (MRI) has shown limited diagnostic accuracy for multiple ligament knee injuries (MLKIs), especially posterolateral corner (PLC) injuries.

Hypothesis:

The diagnostic accuracy of MRI for MLKIs will only be moderate for some knee structures. Patient-related factors and injury patterns could modify the diagnostic accuracy of MRI.

Study Design:

Cohort study; Level of evidence, 3.

Methods:

All patients with MLKIs surgically treated between January 2014 and December 2020 in the centers participating in the study were reviewed. We recorded sex, age, mechanism of injury, time from injury to MRI, and vascular and neurological associated lesions. Lesions to the anterior cruciate ligament (ACL), posterior cruciate ligament, medial collateral ligament, lateral collateral ligament (LCL), popliteus tendon, popliteofibular ligament, iliotibial band, biceps tendon, medial and lateral meniscus, and articular cartilage from MRI reports and surgical records were also collected. The sensitivity, specificity, positive predictive value, negative predictive value, diagnostic accuracy, diagnostic odds ratio, positive and negative likelihood ratio, and intraclass correlation coefficient of MRI were calculated for each knee structure. With logistic regression, associations between patient and injury characteristics and MRI accuracy were assessed.

Results:

A total of 178 patients (127 male; mean age, 33.1 years) were included. High-energy trauma was the most common mechanism of injury (50.6%), followed by sports trauma (38.8%) and low-energy trauma (8.4%). The ACL was the structure with the best diagnostic accuracy, diagnostic odds ratio, and positive predictive value (94.4%, 113.2, and 96.8%, respectively). PLC structures displayed the worst diagnostic accuracy among knee ligaments (popliteus tendon: 76.2%; LCL: 80.3%) and diagnostic odds ratio (popliteus tendon: 9.9; LCL: 17.0; popliteofibular ligament: 17.5). MRI was more reliable in detecting the absence of meniscal and chondral lesions than in identifying them. Logistic regression found that the diagnostic accuracy was affected by the Schenck classification, with higher Schenck grades having worse diagnostic accuracy for peripheral structures (iliotibial band, popliteus tendon, and biceps tendon) and improved diagnostic accuracy for the ACL and posterior cruciate ligament.

Conclusion:

The diagnostic accuracy of MRI for MLKIs largely varied among knee structures, with many of them at risk of a misdiagnosis, especially PLC, meniscal, and chondral lesions. The severity of MLKIs lowered the diagnostic accuracy of MRI for peripheral structures.
Energy absorption capability of carbon/epoxy composite laminates: A novel numerical approach
Authors: Engül Mehmet C , Ersoy Nuri
Published: January 2023

While composite structures absorb energy well during crash events, crush-induced failure mechanisms and their effects on energy absorption characteristics are still unclear. Due to the complexity of the process, Finite Element (FE) models applied to estimate energy absorption capability of composite structures require a considerable amount of computational time. This study presents a novel numerical approach for the crushing process of AS4/8852 flat coupon plates in which computational cost is decreased by reducing the number of interfaces between plies and modifying the relevant properties. Experimental and numerical studies are conducted for cross-ply specimens [0/90]ns in order to understand and discuss the failure mechanisms occurring during the crushing process in detail and the influence of plate thickness on Specific Energy Absorption (SEA). Moreover, to demonstrate the validity of novel FE model for different stacking sequences, same approach is applied to the [0/45/0/−45]s plate geometry. By this method, run time is decreased by more than 50%.
Preparing Indigenous School Psychologists: Stories From an Indigenous Specialization Project in School Psychology
Authors: Robinson-Zañartu Carol , Kinlicheene Bryanna , Neztsosie Nora
Published: January 2023

Educational disparities between Indigenous and non-Indigenous youth across Canada, as is true across the United States, pose challenges to education systems to examine and alter professional practices in ways that support closing these gaps. Calls for more Indigenous school psychologists who might bring skills and perspectives to bear are long-standing, yet few graduate preparation programs have responded. Whether Indigenous students begin and do not complete programs, or never apply, it is incumbent on programs to examine the systemic underpinnings of the problem and respond with culturally responsive recruitment and retention strategies. In this article, one school psychology program shares programmatic contexts, recruitment processes, and retention strategies that have supported the preparation and graduation of dozens of Indigenous school psychologists from multiple Indigenous nations.
Exploring the Perspectives of Adults Aging With Long-Term Physical Disabilities on Physical Activity: A Qualitative Study
Authors: Heeb Desai Rachel , Kiserow Rachel , Mullings Alicia , Smith Megan , Tucker Susan , Eyler Amy , Stark Susan , Morgan Kerri
Published: January 2023

Background

Adults aging with long-term physical disabilities (AAwPD) face personal and environmental barriers to living independently, but little is known about their perspectives on and experiences with physical activity (PA).

Purpose

The purpose of this study was to explore the perspectives of AAwPD on PA.

Research Design

Qualitative semi-structured interviews with AAwPD were conducted virtually via phone or videoconference.

Study Sample

A convenience sample of AAwPD aged 45-65 and living with a physical disability for at least 5 years was recruited through aging organizations, disability organizations, and social media in St. Louis, Missouri until thematic saturation was reached (n = 20).

Data Collection and Analysis

Participants were asked semi-structured interview questions about their perspectives and experiences with PA following an interview guide developed by disability, aging, and qualitative research experts. Data were analyzed using text analysis in NVivo 12. Codes were developed into themes by the research team and validated using member checking methods.

Results

Four themes emerged from the data: barriers and facilitators to engaging in PA, motivations and beliefs regarding PA, benefits of PA, and PA routines and habits. Participants reported a desire to engage in more PA but described barriers such as pain and fatigue symptoms, secondary health conditions, lack of social support, and fear of falling. Accessibility of facilities and equipment (eg, lack of ramps or equipment not at wheelchair height) and transportation barriers (eg, inconvenient schedules or excessive wait times) were specifically described as major environmental barriers.

Conclusion

Most participants’ reported PA routines did not meet the quantity or intensity levels recommended by current guidelines. These results may help inform healthcare providers, community programs, and future interventions to improve PA levels for AAwPD, an underserved but growing demographic.
Effects of mixed marshalling modes on longitudinal freight train dynamics
Authors: Yang Liangliang , Luo Shihui , Fu Maohai , Wang Chen
Published: January 2023

Mixed freight trains have more diversified vehicle characteristics and train combination modes than unified freight trains, so it is more difficult for mixed freight trains to predict the accident caused by longitudinal impulse. At present, train dynamics theories and numerical simulation methods have been increasingly used to reduce longitudinal train impulse and decrease freight wagon instability. According to these research experiences, this paper focuses on the marshalling modes of mixed freight trains and their effects on the longitudinal in-rain forces. For this purpose, an advanced simulation model for mixed freight trains was developed and several typical mixed marshalling modes were designed and simulated. The results indicate that, for the mixed train including empty and loaded wagons, empty wagons should be arranged at the tail of the train and should avoid being marshalled together. For the mixed train including marshalled wagons with various actual live loads or nominal axle loads, heavier wagons should be centrally arranged in the front part of the train, and meanwhile marshalled wagons should avoid being sorted by weight in the concave and ascending distribution mode. For the mixed train including marshalled wagons with various body types, container flat wagons and oil tank wagons should be arranged as much as possible in the front of the other wagons.
Mitochondrial ROS induced by ML385, an Nrf2 inhibitor aggravates the ferroptosis induced by RSL3 in human lung epithelial BEAS-2B cells
Authors: Taufani Indra Putra , Situmorang Jiro Hasegawa , Febriansah Rifki , Tasminatun Sri , Sunarno Sunarno , Yang Liang-Yo , Chiang Yi-Ting , Huang Chih-Yang
Published: January 2023

Ferroptosis is a new type of cell death marked by iron and lipid ROS accumulation. GPX4 is one of the glutathione peroxidases known to regulate ferroptosis tightly. On the other hand, Nrf2 also plays a vital role in ferroptosis as it targets genes related to oxidant defense. Herein, we employed beas-2 human epithelial cells treated with a low concentration of RSL3 to induce ferroptosis. To study the protective role of Nrf2, we used ML385 as its specific inhibitor. A combination of ML385 and a low concentration of RSL3 synergistically induced more toxicity to RSL3. Furthermore, we found that mitochondrial ROS is elevated in ML385 and RSL3 combination group. In addition, Mito TEMPOL application successfully prevents the upregulation of mitochondrial ROS, lipid ROS, reduces the toxicity of RSL3, restores the antioxidant capacity of the cells, and mitochondrial functions reflected by mitochondrial membrane potential and mitochondrial oxidative phosphorylation system (OXPHOS) expression. Altogether, our study demonstrated that Nrf2 inhibition by ML385 induces more toxicity when combined with RSL3 through the elevation of mitochondrial ROS and disruption of mitochondrial function.
Like a Pig in Mud: Rejecting the Manicured Boundaries of the Patriarchy
Authors: Weiser S. Gavin , DeMartino Linsay , Stasicky Alyssa
Published: January 2023

How do school leaders make sense of the mess of the regimes of the normal (Warner, 1993) when they themselves are beyond the norm? While we may be beyond the normal, we are also “awash in the flow of the everyday” (Manalansan, 2018, p. 2). Though we may resist and see ourselves as beyond the norm (Weiser et al., 2019), we are never “in a position of exteriority in relation” (Foucault, 1978, p. 95) to the norms of power. Using data from several different projects collected over the past several years, we conceptualize a new way to consider not only data, but also how embracing new formations of leadership, which may appear messy, can work toward liberatory praxis. Drawing upon our archive of previous projects (DeMartino & Weiser, 2021; Weiser, 2018; Weiser et al., 2019, DeMartino, 2020) that have been published, as well as completed but not-yet-published projects, we funk (Warner, 1993) up our relations to these archives (Cvetkovich, 2003; Manalansan, 2014) to uncover how we have been engaged in the act of making a mess through our research. Parallel to the idea of failure as distinctly queer (Halberstam, 2011),we aim to understand how engaging in the messiness of identity-based research using art and visual methods (Leavy, 2017) can provide pathways forward for educational leaders who are willing to get dirty in order to support members of the educational community who do not fit cleanly into cisheteropatriarchal standards.
Ethical Issues and Ethical Traps
Authors: Bradley Loretta J.
Published: January 2023

Ethics in its most basic form refers to doing what is right. This article focuses on four ethical traps to help couple and family counselors not only recognize ethical traps but in addition to understand how to avoid and solve ethical traps. To help the couple and family counselor better understand the principles involving ethical traps, four case studies are presented.
Tracheal Bronchus and Successful Right-Sided Isolation With a Bronchial Blocker
Authors: Tang Jonathan E. , Tybout Caroline E. , Csernak Lidia M. , Awad Hamdy , Benavidez Pamela P. , Essandoh Michael K.
Published: January 2023

The presence of a tracheal bronchus, which is often incidentally discovered, complicates endotracheal intubation and lung isolation during thoracic surgery. Prior reports of successful right-sided lung isolation in the presence of tracheal bronchus required utilization of a double lumen tube. Although right-sided lung isolation was required in our case, due to other patient factors, it was determined that a double lumen tube of a suitable size would be unlikely to be placed safely and successfully. We describe the successful use of a Rüsch EZ-Blocker bronchial blocker in obtaining right-sided isolation in a patient with a difficult airway and tracheal bronchus.
For a political conception of multicultural citizenship
Authors: Gianni Matteo
Published: January 2023

Multicultural citizenship has provided a terrific liberal philosophical framework to justify respect for cultural minorities and their fair accommodation in contexts marked by cultural disadvantages. However, the importance it provides to societal culture in order to fulfil individual's autonomy entails a metaphysical aspect (i.e societal culture as an instrumental condition for autonomy) which calls into question the full inclusion of all individuals in multicultural societies. This paper maintains that the conception of citizenship in Multicultural citizenship should be independent of metaphysical assumptions and strengthen in its political underpinnings. Kymlicka's view on citizenship is based on liberal rights and the constitutional recognition of minorities. It does not address the process of citizenship, and how a conception of performative citizenship can be conceived to address claims for recognition in ways that produce legitimate, inclusive and inter-subjectively shared outcomes, especially with regard to an inclusive national identity. Multicultural citizenship provides principled legal modalities to accommodate multicultural societies, but does not clearly address the political modalities supporting such accommodations. It thus entails a danger of a de-politicization of citizenship; and a de-politicized citizenship, is not citizenship anymore. The article tasks to figuring out the political and democratic conditions allowing accommodations to be endorsed by all affected individuals in the name of a common and justified conception of democratic citizenship and inclusive conception of the nation.
Bodies of Walking: Trans-Materializing the Experiences of Racial Harassment
Authors: Zarabadi Shiva
Published: January 2023

Partaking in some of the material and affective moments and movements that emerged from my PhD research, I map the ontological, epistemological, and ethical possibilities/impossibilities that trans-corporeality and trans-materiality open in my research. Using walking and photo-diary as PhEmaterialist multisensory methodologies, I followed 15 Muslim schoolgirls in two London secondary schools (East Dulwich and Bethnal Green) mapping relational materialities between things that matter for them in their ordinary everyday practices and experiences. Employing Jane Bennett’s creative and absorbent I as a partaker rather than either actor or recipient, taking in and being taken up by virtues specific to the moment, this article materializes some partaker agencies and “more-thans” that Maha (my PhD participant) and I walked, made, challenged, and became with in different “spacetimematterings.” I argue that social injustice and inequalities, gendered and racial harassment as political, ethical, and material issues, are not always raised by those represented or able to name and speak up as part of social structures but emerge through complex webs of power relations and ordinary, everyday material moments and affective encounters. I consider bodies of walking as partakers of influx and efflux, many “I”s, moving and making the moments and experiences of racial harassment, affective entanglements, and the potentialities of the virtual, material, and affective that emerge in-between human and more-than-human walking bodies.
Two Molecular Weights Holothurian Glycosaminoglycan and Hematoporphyrin Derivative-Photodynamic Therapy Inhibit Proliferation and Promote Apoptosis of Human Lung Adenocarcinoma Cells
Authors: Hao-Yu Dai , Ding-Yi Yu , Bao-Hong Xiao , Aihua Sui , Xiao-Qian Ding , Cun-Zhi Lin
Published: January 2023

Holothurian glycosaminoglycan (hGAG) is extracted from the body wall of the sea cucumber, and previous studies have shown many unique bioactivities of hGAG, including antitumor, anti-angiogenesis, anti coagulation, anti thrombosis, anti-inflammation, antidiabetic effect, antivirus, and immune regulation. The effects of 3W and 5W molecular weights hGAG with hematoporphyrin derivative-photodynamic therapy (HPD-PDT) on lung cancer were investigated. Human lung adenocarcinoma A549 cells were divided into 6 groups: control group, 3W molecular weight hGAG group, 5W molecular weight hGAG group, HPD-PDT group, 3W molecular weight hGAG + HPD-PDT group, and 5W molecular weight hGAG + HPD-PDT group. Cell morphology was observed under inverted phase contrast microscope. Cell proliferative activity was detected by CCK8 and cell apoptosis was assayed by Hoechst33258 staining and flow cytometry. The results showed that two different molecular weights hGAG could inhibit proliferation, promote apoptosis rates of A549 cells, and enhance the sensitivity of A549 cells to HPD-PDT. The combined use of hGAG and HPD-PDT has synergistic inhibitory effects on A549 cells, and the effects of 3W molecular weight hGAG are better than that of 5W molecular weight hGAG.