bluuebunny/crossref_metadata_2025 huggingface dataset:
Anthropometry and high-speed resistive exercise performance by male athletes
Authors: Mitchell Lacey N. , Perry Rachel A. , Martin Jake L. , Vickers Samantha D. , Baptista Rachel A. , Clark Ashley N. , McArtor Jon D. , Caruso John F.
Published: November 2015

BACKGROUND: High-speed exercise is an essential training component to prepare athletes for competition. To date correlations between anthropometry and high-speed exercise performance are mixed.

OBJECTIVE: To assess anthropometry as a correlate to performance from workouts comprised exclusively of tonic or phasic repetitions done on a high-speed resistive exercise device (Impulse Training Systems; Newnan, GA).

METHODS: Male athletes (n = 31) did two workouts that involved performance of a standing unilateral rowing motion with their left arm for two 60-second sets. Each workout was comprised solely of tonic or phasic repetitions. Anthropometric measurements included: height, mass, body fat percentage, shoulder width, upper and lower arm lengths as well as torso length. Mean force and total work values from each type of workout served as criterion variables.

RESULTS: Anthropometry predicted significant amounts of variance for both mean force and total work values (r2 ∼ 0.21) from tonic workouts. However anthropometry failed to predict a significant amount of performance variance from phasic workouts.

CONCLUSIONS: Anthropometry acts as a better correlate to high-speed resistive exercise performance for repetitions that do not terminate with impact forces and are inherently less ballistic, as the latter likely utilizes less momentum.
Clinicopathologic characteristics and treatment of marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma)
Authors: Raderer Markus , Kiesewetter Barbara , Ferreri Andrés J. M.
Published: November 2015

Answer questions and earn CME/CNE

Extranodal marginal zone lymphoma of the mucosa‐associated lymphoid tissue (MALT lymphoma) accounts for 7% to 8% of newly diagnosed lymphomas. Because of its association with infectious causes, such as Helicobacter pylori (HP) or Chlamydophila psittaci (CP), and autoimmune diseases, it has become the paradigm of an antigen‐driven malignancy. MALT lymphoma usually displays an indolent course, and watch‐and‐wait strategies are justified initially in a certain percentage of patients. In patients with gastric MALT lymphoma or ocular adnexal MALT lymphoma, antibiotic therapy against HP or CP, respectively, is the first‐line management of choice, resulting in lymphoma response rates from 75% to 80% after HP eradication and from 33% to 65% after antibiotic therapy for CP. In patients who have localized disease that is refractory to antibiotics, radiation is widely applied in various centers with excellent local control, whereas systemic therapies are increasingly being applied, at least in Europe, because of the potentially systemic nature of the disease. Therefore, the objective of this review is to briefly summarize the clinicopathologic characteristics of this distinct type of lymphoma along with current data on management strategies. CA Cancer J Clin 2016;66:152–171. © 2015 American Cancer Society.
A New Approach for Automatic Removal of Movement Artifacts in Near-Infrared Spectroscopy Time Series by Means of Acceleration Data
Authors: Metz Andreas , Wolf Martin , Achermann Peter , Scholkmann Felix
Published: November 2015

Near-infrared spectroscopy (NIRS) enables the non-invasive measurement of changes in hemodynamics and oxygenation in tissue. Changes in light-coupling due to movement of the subject can cause movement artifacts (MAs) in the recorded signals. Several methods have been developed so far that facilitate the detection and reduction of MAs in the data. However, due to fixed parameter values (e.g., global threshold) none of these methods are perfectly suitable for long-term (i.e., hours) recordings or were not time-effective when applied to large datasets. We aimed to overcome these limitations by automation, i.e., data adaptive thresholding specifically designed for long-term measurements, and by introducing a stable long-term signal reconstruction. Our new technique (“acceleration-based movement artifact reduction algorithm”, AMARA) is based on combining two methods: the “movement artifact reduction algorithm” (MARA, Scholkmann et al. Phys. Meas. 2010, 31, 649–662), and the “accelerometer-based motion artifact removal” (ABAMAR, Virtanen et al. J. Biomed. Opt. 2011, 16, 087005). We describe AMARA in detail and report about successful validation of the algorithm using empirical NIRS data, measured over the prefrontal cortex in adolescents during sleep. In addition, we compared the performance of AMARA to that of MARA and ABAMAR based on validation data.
Role of α and β Transmembrane Domains in Integrin Clustering
Authors: Shamloo Amir , Golgoon Ashkan , Zadeh Ebrahim
Published: November 2015

Integrins are transmembrane proteins playing a crucial role in the mechanical signal transduction from the outside to the inside of a cell, and vice versa. Nevertheless, this signal transduction could not be implemented by a single protein. Rather, in order for integrins to be able to participate in signal transduction, they need to be activated and produce clusters first. As integrins consist of α- and β-subunits that are separate in the active state, studying both subunits separately is of a great importance, for, in the active state, the distance between α- and β-subunits is long enough that they do not influence one another significantly. Thus, this study aims to investigate the tendency of transmembrane domains of integrins to form homodimers. We used both Steered and MARTINI Coarse-grained molecular dynamics method to perform our simulations, mainly because of a better resolution and computational feasibility that each of these methods could provide to us. Using the Steered molecular dynamics method for α- and β-subunits, we found that the localized lipid packing prevented them from clustering. Nonetheless, the lipid packing phenomenon was found to be an artifact after investigating this process using a coarse grained (CG) model. Exploiting the coarse-grained molecular dynamics simulations, we found that α- and β-subunits tend to form a stable homo-dimer.
Antioxidant White Grape Seed Phenolics: Pressurized Liquid Extracts from Different Varieties
Authors: Garcia-Jares Carmen , Vazquez Alberto , Lamas Juan , Pajaro Marta , Alvarez-Casas Marta , Lores Marta
Published: November 2015

Grape seeds represent a high percentage (20% to 26%) of the grape marc obtained as a byproduct from white winemaking and keep a vast proportion of grape polyphenols. In this study, seeds obtained from 11 monovarietal white grape marcs cultivated in Northwestern Spain have been analyzed in order to characterize their polyphenolic content and antioxidant activity. Seeds of native (Albariño, Caiño, Godello, Loureiro, Torrontés, and Treixadura) and non-native (Chardonnay, Gewurtzträminer, Pinot blanc, Pinot gris, and Riesling) grape varieties have been considered. Low weight phenolics have been extracted by means of pressurized liquid extraction (PLE) and further analyzed by LC-MS/MS. The results showed that PLE extracts, whatever the grape variety of origin, contained large amounts of polyphenols and high antioxidant activity. Differences in the varietal polyphenolic profiles were found, so a selective exploitation of seeds might be possible.
Extremely Nonlinear Optics Using Shaped Pulses Spectrally Broadened in an Argon- or Sulfur Hexafluoride-Filled Hollow-Core Fiber
Authors: Hoffmann Andreas , Zürch Michael , Spielmann Christian
Published: November 2015

In this contribution we present a comparison of the performance of spectrally broadened ultrashort pulses using a hollow-core fiber either filled with argon or sulfur hexafluoride (SF6) for demanding pulse-shaping experiments. The benefits of both gases for pulse-shaping are studied in the highly nonlinear process of high-harmonic generation. In this setup, temporally shaping the driving laser pulse leads to spectrally shaping of the output extreme ultraviolet (XUV) spectrum, where total yield and spectral selectivity in the XUV are the targets of the optimization approach. The effect of using sulfur hexafluoride for pulse-shaping the XUV yield can be doubled compared to pulse compression and pulse-shaping using argon and the spectral range for selective optimization of a single harmonic can be extended. The obtained results are of interest for extending the range of ultrafast science applications drawing on tailored XUV fields.
Investigations of the Diurnal Variation of Vertical HCHO Profiles Based on MAX-DOAS Measurements in Beijing: Comparisons with OMI Vertical Column Data
Authors: Lee Hanlim , Ryu Jaeyong , Irie Hitoshi , Jang Seong-Ho , Park Junsung , Choi Wonei , Hong Hyunkee
Published: November 2015

An investigation into the diurnal characteristics of vertical formaldehyde (HCHO) profiles was conducted based on multi-axis differential optical absorption spectroscopy (MAX-DOAS) measurements in Beijing during the CAREBEIJING campaign, covering a month-long period through August and September 2006. Vertical HCHO profiles were retrieved based on a combined differential optical absorption spectroscopy (DOAS) technique and an optimal estimation method (OEM). The HCHO volume-mixing ratio (VMR) was found to be highest in the layer from the surface up to an altitude of 1 km and to decrease with altitude above this layer. In all retrieved profiles, HCHO was not detected in the layer from 3–4 km. Over the diurnal cycle, the HCHO VMR values were generally highest at 15:00 local time (LT) and were lower in the morning and late afternoon. The mean HCHO VMRs were 6.17, 1.82, and 0.80 ppbv for the 0–1, 1–2, and 2–3-km layers, respectively, at 15:00 LT, whereas they were 3.54 (4.79), 1.06 (1.43), and 0.46 (0.63) ppbv for the 0–1, 1–2, and 2–3-km layers, respectively, at 09:00 (17:00) LT. The HCHO VMRs reached their highest values at 15:00 LT on August 19, which were 17.71, 5.20, and 2.31 ppbv for the 0–1, 1–2, and 2–3-km layers, respectively. This diurnal pattern implies that the photo-oxidation of volatile organic compounds (VOCs) was most active at 15:00 LT for several days during the campaign period. In a comparison of the derived HCHO VCDs with those obtained from the Ozone Monitoring Instrument (OMI) measurements, the HCHO vertical column density (VCD) values obtained from the OMI measurements tend to be smaller than those from the MAX-DOAS.
Effects of Vanadium/Nickel Contents in Laves Phase-Related Body-Centered-Cubic Solid Solution Metal Hydride Alloys
Authors: Young Kwo-hsiung , Wong Diana , Nei Jean
Published: November 2015

Structural, gaseous phase hydrogen storage, and electrochemical properties of a series of annealed (900 °C for 12 h) Laves phase-related body-centered-cubic (BCC) solid solution metal hydride (MH) alloys with vanadium/nickel (V/Ni) contents ranging from 44/18.5 to 28/34.5 were studied. As the average Ni-content increases, C14 phase evolves into the C15 phase and a new σ-VNi phase emerges; lattice constants in BCC, C14, and TiNi phase all decrease; the main plateau pressure increases; both gaseous phase and electrochemical hydrogen storage capacities decrease; the pressure-concentration-temperature (PCT) absorption/desorption hysteresis decreases; both high-rate dischargeability (HRD) and bulk hydrogen diffusivity increase and then decrease; and the surface reaction current decreases. There is a capacity-rate tradeoff with the change in V/Ni content. Alloys with relatively lower Ni-content show higher capacities but inferior high-rate performance compared to commercially available AB5 MH alloy. Increasing the Ni-content in this BCC-based multi-phase alloy can improve the high-rate capability over AB5 alloy but with lower discharge capacities. The inferior surface reaction current in these alloys, compared to AB5, may be due to the smaller surface area, not the total volume, of the Ni clusters embedded in the surface oxide layer of the activated alloys.
DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles’ Heel of Cancer
Authors: Velic Denis , Couturier Anthony , Ferreira Maria , Rodrigue Amélie , Poirier Guy , Fleury Fabrice , Masson Jean-Yves
Published: November 2015

For decades, radiotherapy and chemotherapy were the two only approaches exploiting DNA repair processes to fight against cancer. Nowadays, cancer therapeutics can be a major challenge when it comes to seeking personalized targeted medicine that is both effective and selective to the malignancy. Over the last decade, the discovery of new targeted therapies against DNA damage signalling and repair has offered the possibility of therapeutic improvements in oncology. In this review, we summarize the current knowledge of DNA damage signalling and repair inhibitors, their molecular and cellular effects, and future therapeutic use.
Role of microRNAs in Alcohol-Induced Multi-Organ Injury
Authors: Natarajan Sathish , Pachunka Joseph , Mott Justin
Published: November 2015

Alcohol consumption and its abuse is a major health problem resulting in significant healthcare cost in the United States. Chronic alcoholism results in damage to most of the vital organs in the human body. Among the alcohol-induced injuries, alcoholic liver disease is one of the most prevalent in the United States. Remarkably, ethanol alters expression of a wide variety of microRNAs that can regulate alcohol-induced complications or dysfunctions. In this review, we will discuss the role of microRNAs in alcoholic pancreatitis, alcohol-induced liver damage, intestinal epithelial barrier dysfunction, and brain damage including altered hippocampus structure and function, and neuronal loss, alcoholic cardiomyopathy, and muscle damage. Further, we have reviewed the role of altered microRNAs in the circulation, teratogenic effects of alcohol, and during maternal or paternal alcohol consumption.
Recent Advances in Electrochemical Biosensors Based on Fullerene-C60 Nano-Structured Platforms
Authors: Pilehvar Sanaz , De Wael Karolien
Published: November 2015

Nanotechnology is becoming increasingly important in the field of (bio)sensors. The performance and sensitivity of biosensors is greatly improved with the integration of nanomaterials into their construction. Since its first discovery, fullerene-C60 has been the object of extensive research. Its unique and favorable characteristics of easy chemical modification, conductivity, and electrochemical properties has led to its tremendous use in (bio)sensor applications. This paper provides a concise review of advances in fullerene-C60 research and its use as a nanomaterial for the development of biosensors. We examine the research work reported in the literature on the synthesis, functionalization, approaches to nanostructuring electrodes with fullerene, and outline some of the exciting applications in the field of (bio)sensing.
Diet and Pancreatic Cancer Prevention
Authors: Casari Ilaria , Falasca Marco
Published: November 2015

Pancreatic cancer is without any doubt the malignancy with the poorest prognosis and the lowest survival rate. This highly aggressive disease is rarely diagnosed at an early stage and difficult to treat due to its resistance to radiotherapy and chemotherapy. Therefore, there is an urgent need to clarify the causes responsible for pancreatic cancer and to identify preventive strategies to reduce its incidence in the population. Some circumstances, such as smoking habits, being overweight and diabetes, have been identified as potentially predisposing factors to pancreatic cancer, suggesting that diet might play a role. A diet low in fat and sugars, together with a healthy lifestyle, regular exercise, weight reduction and not smoking, may contribute to prevent pancreatic cancer and many other cancer types. In addition, increasing evidence suggests that some food may have chemo preventive properties. Indeed, a high dietary intake of fresh fruit and vegetables has been shown to reduce the risk of developing pancreatic cancer, and recent epidemiological studies have associated nut consumption with a protective effect against it. Therefore, diet could have an impact on the development of pancreatic cancer and further investigations are needed to assess the potential chemo preventive role of specific foods against this disease. This review summarizes the key evidence for the role of dietary habits and their effect on pancreatic cancer and focuses on possible mechanisms for the association between diet and risk of pancreatic cancer.
Two Carbonylations of Methyl Iodide and Trimethylamine to Acetic acid and N,N-Dimethylacetamide by Rhodium(I) Complex: Stability of Rhodium(I) Complex under Anhydrous Condition
Authors: Hong Jang-Hwan
Published: November 2015

Rhodium(I)-complex [Rh(CO)2I2−] (1) catalyzed two carbonylations of methyl iodide and trimethylamine in NMP (1-methyl-2-pyrolidone) to acetic acid and DMAC (N,N-dimethylacetamide) in the presence of calcium oxide and water. The carbonylation of trimethylamine continued during the carbonylation and consumption of methyl iodide. In total, 183.8 mmol of carbonylated products was produced while consuming 24.1 mmol methyl iodide via acetic acid formation. These results clearly indicated that there were two carbonylation routes of trimethylamine and methyl iodide and the carbonylation rate of trimethylamine was faster than that of methyl iodide. Rhodium(I)-complex [Rh(CO)2I2]− (1) in the presence of trimethylamine was stable enough to be used 25 times with TON (Turnover Number) of 368 for DMAC and TON of 728 for trimethylamine. Inner-sphere reductive elimination in stepwise procedure was suggested for the formation of DMAC instead of acyl iodide intermediate under anhydrous condition.
Dominant Strategies of Quantum Games on Quantum Periodic Automata
Authors: Giannakis Konstantinos , Papalitsas Christos , Kastampolidou Kalliopi , Singh Alexandros , Andronikos Theodore
Published: November 2015

Game theory and its quantum extension apply in numerous fields that affect people’s social, political, and economical life. Physical limits imposed by the current technology used in computing architectures (e.g., circuit size) give rise to the need for novel mechanisms, such as quantum inspired computation. Elements from quantum computation and mechanics combined with game-theoretic aspects of computing could open new pathways towards the future technological era. This paper associates dominant strategies of repeated quantum games with quantum automata that recognize infinite periodic inputs. As a reference, we used the PQ-PENNY quantum game where the quantum strategy outplays the choice of pure or mixed strategy with probability 1 and therefore the associated quantum automaton accepts with probability 1. We also propose a novel game played on the evolution of an automaton, where players’ actions and strategies are also associated with periodic quantum automata.
The Scalp Has a Lower Stratum Corneum Function with a Lower Sensory Input than Other Areas of the Skin Evaluated by the Electrical Current Perception Threshold
Authors: Takagi Yutaka , Takatoku Hiroko , Terazaki Hiroyuki , Nakamura Tadashi , Ishida Koichi , Kitahara Takashi
Published: November 2015

Many people feel frequent prickling or itching sensations on their scalp. The scalp is an atypical area of the skin since it is normally covered with thick hair and has many sebaceous glands and sweat glands. The scalp often has skin problems that can affect its sensitivity and functions. However, not much is known about stratum corneum function and the neural sensitivity of the scalp. Here we evaluated stratum corneum function and the neural sensitivity of the scalp of 47 normal male individuals in various skin conditions and compared the results to that to the forehead. The neural sensitivity was evaluated by measuring the electrical current perception threshold (CPT). The cutaneous barrier function and stratum corneum moisture-retention ability (MRA) of the scalp were significantly lower than on the forehead, even if there were some scalp problems. Depending on the increase in severity of scalp skin problems, both these skin functional properties and the CPT decreased significantly. However, regardless of its lower functional properties, scalp skin was not significantly lower than that of the forehead. Although the scalp has a low stratum corneum function compared with the forehead and has easily induced skin problems, the scalp skin has less sensitive sensory nerves, resulting in experiencing a worsening of scalp symptoms more easily.
Enthalpies of Formation of Transition Metal Diborides: A First Principles Study
Authors: Colinet Catherine , Tedenac Jean-Claude
Published: November 2015

The enthalpies of formation of transition metals diborides in various structures have been obtained from density functional theory (DFT) calculations in order to determine the ground state at T = 0 K and p = 0. The evolution of the enthalpies of formation along the 3D, 4D, and 5D series has been correlated to the considered crystal structures. In the whole, the calculated values of the enthalpies of formation of the diborides in their ground state are in good agreement with the experimental ones when available. The calculated values of the lattice parameters at T = 0 K of the ground state agree well with the experimental values. The total and partial electronic densities of states have been computed. Special features of the transition metal electronic partial density of states have been evidenced and correlated to the local environment of the atoms.
Liquid-Assisted Grinding to Prepare a Cocrystal of Adefovir Dipivoxil Thermodynamically Less Stable than Its Neat Phase
Authors: Jung Sungyup , Choi Insil , Kim Il
Published: November 2015

Liquid-assisted grinding was employed to generate a cocrystal of adefovir dipivoxil (AD) and glutaric acid (GLU), which had not been successfully obtained through solution crystallization. The cocrystal formation was confirmed with powder X-ray diffraction, and its thermal stability and release behavior were studied through differential scanning calorimetry and dissolution experiments, respectively. The AD/GLU cocrystal was less stable than neat AD phase and the previously reported AD cocrystals with other dicarboxylic acids, such as suberic acid and succinic acid. This suggests that the intermolecular interactions of the AD/GLU cocrystal are probably weaker than the other crystal phases. The release behavior of the AD/GLU was comparable with the cocrystal with suberic acid. The current study verifies the effectiveness of the liquid-assisted grinding for the preparation of the thermodynamically less stable cocrystal phase.
Risk Factors for Possible Dementia Using the Hopkins Verbal Learning Test and the Mini-Mental State Examination in Shanghai
Authors: Xu Xin , Xiao Shifu , Rahardjo Tri , Hogervorst Eef
Published: November 2015

Using a combination of the Hopkins Verbal Learning Test (HVLT) and the Mini-Mental State Examination (MMSE), we investigated the prevalence of possible dementia (DEM) in community-dwelling elderly in Shanghai. Subsequently, we investigated significant risk factors for DEM and generated a DEM self-checklist for early DEM detection and case management. We found that among a total of 521 participants using a HVLT cut-off score of <19 and a MMSE cut-off score of <24, a total of 69 DEM cases were identified. Risk factors, such as advanced age (≥68 years), low education (no or primary level), self-reported history of hypertension, and self-reported subjective memory complaints (SMC) were significantly predictive of DEM. The presence of ≥3 out of four of the above mentioned risk factors can effectively discriminate DEM cases from non-DEM subjects.
Forecast Combination under Heavy-Tailed Errors
Authors: Cheng Gang , Wang Sicong , Yang Yuhong
Published: November 2015

Forecast combination has been proven to be a very important technique to obtain accurate predictions for various applications in economics, finance, marketing and many other areas. In many applications, forecast errors exhibit heavy-tailed behaviors for various reasons. Unfortunately, to our knowledge, little has been done to obtain reliable forecast combinations for such situations. The familiar forecast combination methods, such as simple average, least squares regression or those based on the variance-covariance of the forecasts, may perform very poorly due to the fact that outliers tend to occur, and they make these methods have unstable weights, leading to un-robust forecasts. To address this problem, in this paper, we propose two nonparametric forecast combination methods. One is specially proposed for the situations in which the forecast errors are strongly believed to have heavy tails that can be modeled by a scaled Student’s t-distribution; the other is designed for relatively more general situations when there is a lack of strong or consistent evidence on the tail behaviors of the forecast errors due to a shortage of data and/or an evolving data-generating process. Adaptive risk bounds of both methods are developed. They show that the resulting combined forecasts yield near optimal mean forecast errors relative to the candidate forecasts. Simulations and a real example demonstrate their superior performance in that they indeed tend to have significantly smaller prediction errors than the previous combination methods in the presence of forecast outliers.
Will the Use of Contextual Indicators Make UK Higher Education Admissions Fairer?
Authors: Boliver Vikki , Gorard Stephen , Siddiqui Nadia
Published: November 2015

In the UK, as elsewhere, the use of ‘contextual’ data has been strongly advocated in order to inform undergraduate admissions decision-making. More than a third of UK universities currently take the socioeconomic or other background context of undergraduate applicants’ attainment into account when deciding whom to shortlist, interview, make standard or reduced offers to, or accept at confirmation or clearing. Even more universities plan to do so in the future. Contextualised admissions policies are considered by many commentators to be intrinsically fairer, and to represent a potentially powerful means of addressing the persistent under-representation of HE students from less advantaged backgrounds, but their impact has not yet been rigorously evaluated. In order to be effective, the indicators must be accurate, appropriate, and complete, and policies for their use must demonstrably widen participation, presumably without compromising student achievement. This paper reviews the indicators available for judging context, and the existing evidence base on how contextually-identified students perform in higher education. It illustrates the considerable difficulties of using any available indicators, alone or in combination, in terms of trustworthiness. And it explains how their use could introduce new injustices while tackling merely the symptoms of stratified participation in HE. This is far from a counsel of despair. We need to widen participation and the use of context stills shows considerable promise. The paper therefore presents the case for a new study by the authors, looking at which of the available contextual indicators are best in practice, and what difference their use would really make to widening participation at HE.
Immigrant Children and Youth in the USA: Facilitating Equity of Opportunity at School
Authors: Adelman Howard , Taylor Linda
Published: November 2015

A great deal has been written about immigrant children and youth. Drawing on work done in the USA, this paper focuses on implications for school improvement policy and practice. Discussed are (1) the increasing influx of immigrants into schools; (2) different reasons families migrate; (3) concerns that arise related to immigrant students; (4) prevailing school practices for addressing immigrant concerns; (5) a framework for broadening what schools and communities do; and (6) policy implications, cautions, and recommendations for embedding immigrant concerns into a unified, comprehensive, and equitable system of student and learning supports.
Introduction to the Special Issue on Intelligent and Cooperative Vehicles
Authors: Milanes Vicente
Published: November 2015

Intelligent vehicles constitute one of the hot research topics on the Intelligent Transportation Systems (ITS) field. The development of Advanced Driver Assistance Systems (ADAS) based on multi-fusion information coming from on-board cameras, lidar or radar sensors is leading to more sophisticated passive and active safety systems. Additionally, the growing interest in using wireless communications to connect the vehicle either with other vehicles or the infrastructure is moving the intelligent vehicle research field toward smart interaction, moving to the Cooperative ITS (C-ITS) research field. [...]
Cooling Effect of Water Injection on a High-Temperature Supersonic Jet
Authors: Li Jing , Jiang Yi , Yu Shaozhen , Zhou Fan
Published: November 2015

The high temperature and high pressure supersonic jet is one of the key problems in the design of solid rocket motors. To reduce the jet temperature and noise, cooling water is typically injected into the exhaust plume. Numerical simulations for the gas-liquid multiphase flow field with mixture multiphase model were developed and a series of experiments were carried out. By introducing the energy source terms caused by the vaporization of liquid water into the energy equation, a coupling solution was developed to calculate the multiphase flow field. The temperature data predictions agreed well with the experimental results. When water was injected into the plume, the high temperature core region area was reduced, and the temperature on the head face was much lower than that without water. The relationship between the reduction of temperature on the bottom plate and the momentum ratio is developed, which can be used to predict the cooling effect of water injection in many cases.
Effects of Land Use on Flow Rate Change Indices
Authors: Assani Ali , Delisle Francis , Landry Raphaëlle , Muma Mushombe
Published: November 2015

The goal of this study was to analyze the impact of agriculture on the spatial and temporal variability of flow rate change indices from 1930 to 2008. The two indices used are the coefficient of immoderation (CI) and the coefficient of variation (CV). Values of these two indices are higher for the L’Assomption River agricultural watershed than for the Matawin River forested watershed due to higher runoff in the former than in the latter. The difference in these values between the two watersheds is greater for winter, but it is lower for summer, when the difference in runoff between the two watersheds is strongly attenuated by the presence of crops. Regarding the temporal variability, a difference between the two watersheds is observed in the fall. For the agricultural watershed, mean values of neither index show a break in slope, while a break is observed for the forested watershed. In both watersheds, both indices are positively correlated with maximum temperature and total rainfall in winter, but only to this latter climate variable in the fall. In springtime, the two indices are negatively correlated with minimum temperature in the forested watershed, but only CV is correlated, positively, with this same climate variable in the agricultural watershed.
Development of Novel Textile Bioreactor for Anaerobic Utilization of Flocculating Yeast for Ethanol Production
Authors: Osadolor Osagie , Lennartsson Patrik , Taherzadeh Mohammad
Published: November 2015

Process development, cheaper bioreactor cost, and faster fermentation rate can aid in reducing the cost of fermentation. In this article, these ideas were combined in developing a previously introduced textile bioreactor for ethanol production. The bioreactor was developed to utilize flocculating yeast for ethanol production under anaerobic conditions. A mixing system, which works without aerators, spargers, or impellers, but utilizes the liquid content in the bioreactor for suspending the flocculating yeast to form a fluidized bed, was developed and examined. It could be used with dilution rates greater than 1.0 h−1 with less possibility of washout. The flow conditions required to begin and maintain a fluidized bed were determined. Fermentation experiments with flow rate and utilization of the mixing system as process variables were carried out. The results showed enhanced mass transfer as evidenced by faster fermentation rates on experiments with complete sucrose utilization after 36 h, even at 30 times lesser flow rate.
The Future Internet: A World of Secret Shares
Authors: Buchanan William , Lanc David , Ukwandu Elochukwu , Fan Lu , Russell Gordon , Lo Owen
Published: November 2015

The Public Key Infrastructure (PKI) is crumbling, partially due to the lack of a strong understanding of how encryption actually works, but also due to weaknesses in its implementation. This paper outlines an Internet storage technique using secret sharing methods which could be used to overcome the problems inherent with PKI, while supporting new types of architectures incorporating such things as automated failover and break-glass data recovery. The paper outlines a novel architecture: SECRET, which supports a robust cloud-based infrastructure with in-built privacy and failover. In order to understand the performance overhead of SECRET, the paper outlines a range of experiments that investigate the overhead of this and other secret share methods.
Adding Value to Fruit Processing Waste: Innovative Ways to Incorporate Fibers from Berry Pomace in Baked and Extruded Cereal-based Foods—A SUSFOOD Project
Authors: Rohm Harald , Brennan Charles , Turner Charlotta , Günther Edeltraud , Campbell Grant , Hernando Isabel , Struck Susanne , Kontogiorgos Vassilis
Published: November 2015

This article communicates the set-up of BERRYPOM, a European research project established in the second call of the SUStainable FOOD Production and Consumption (SUSFOOD) network. The project deals with the by-product from berry processing, which is frequently recycled as animal feed, composted or utilized for biogas production. With BERRYPOM it is proposed to analyze the value of berry pomace, to optimize the recovery of bioactive compounds from pomace material, and to incorporate processed berry pomace in cereal-based foods to take advantage of nutritional benefits that originate from its fiber and the content of bioactive substances. Additionally, extraction methods will be evaluated to obtain products rich in phytochemicals, and the influence of processing steps on the antioxidant capacity of pomace will be analyzed. The fiber extracts will then also be utilized in different cereal-based foods and extruded products. As project outcome we expect a substantial increase of knowledge concerning fiber and phytochemicals extraction from berry pomace, its suitability for enhancing nutritional and sensory properties of cereal-based foods, and its effects on the sustainability of the food chain.
Haplotypes and Sequence Variation in the Ovine Adiponectin Gene (ADIPOQ)
Authors: An Qing-Ming , Zhou Hui-Tong , Hu Jiang , Luo Yu-Zhu , Hickford Jon
Published: November 2015

The adiponectin gene (ADIPOQ) plays an important role in energy homeostasis. In this study five separate regions (regions 1 to 5) of ovine ADIPOQ were analysed using PCR-SSCP. Four different PCR-SSCP patterns (A1-D1, A2-D2) were detected in region-1 and region-2, respectively, with seven and six SNPs being revealed. In region-3, three different patterns (A3-C3) and three SNPs were observed. Two patterns (A4-B4, A5-B5) and two and one SNPs were observed in region-4 and region-5, respectively. In total, nineteen SNPs were detected, with five of them in the coding region and two (c.46T/C and c.515G/A) putatively resulting in amino acid changes (p.Tyr16His and p.Lys172Arg). In region-1, -2 and -3 of 316 sheep from eight New Zealand breeds, variants A1, A2 and A3 were the most common, although variant frequencies differed in the eight breeds. Across region-1 and region-3, nine haplotypes were identified and haplotypes A1-A3, A1-C3, B1-A3 and B1-C3 were most common. These results indicate that the ADIPOQ gene is polymorphic and suggest that further analysis is required to see if the variation in the gene is associated with animal production traits.
Manilaner’s Holocaust Meets Manileños’ Colonisation: Cross-Traumatic Affiliations and Postcolonial Considerations in Trauma Studies
Authors: Martin Jocelyn
Published: November 2015

After interrogating the (non-)referential status of the Holocaust for Asians, this essay examines Frank Ephraim’s Escape to Manila and Juergen Goldhagen’s Manila Memories. In particular, cross-traumatic affiliation is studied between two groups of people: the Manilaner and the Manileños: the former were Europeans who fled Nazism and sought refuge in Manila; the latter were Filipino residents of Manila who, during the Second World War, found themselves under Japanese Occupation. A closer reading of the memoirs, however, also reveals latent orientalism in the portrayal of Filipinos. This essay thus echoes present postcolonial concerns in recent Trauma Studies research which ask the place of serial colonisations, martial law, climate catastrophes and the sacred in Trauma theory.
Prevalence of Diabetes and Impaired Fasting Glucose in Hypertensive Adults in Rural China: Far from Leveling-Off
Authors: Yu Shasha , Sun Zhaoqing , Zheng Liqiang , Guo Xiaofan , Yang Hongmei , Sun Yingxian
Published: November 2015

In recent years data from many investigations has shown a leveling–off trend in diabetes incidence. In order to explain the diabetes epidemic in rural China during the past ten years, we conducted a survey from July 2012 to August 2013. Data from comprehensive questionnaires, physical examinations, and blood tests were obtained from 5919 residents with hypertension, aged ≥ 35 years. Diabetes and impaired fasting glucose (IFG) were defined according to the American Diabetes Association (ADA) criteria. The overall prevalence of diabetes and IFG were 15.3% (13.6% in men, 16.8% in women) and 40.7% (44.1% in men, 34.7% in women) in the hypertensive rural Chinese population. The prevalence of previously diagnosed diabetes was 6.5% (4.6% in men, 8.4% in women). The prevalence of undiagnosed diabetes was 8.7% (9.0% in men, 8.5% in women). Multivariate logistic regression revealed that increasing age, drinking, overweight or obesity, systolic blood pressure, low HDL-C, high total cholesterol and triglycerides increased the risk of diabetes (p < 0.05). Diabetes is thus still prevalent in rural areas of China and is manifesting an accelerating trend. It remains an important public health problem in China, especially in rural areas and routine assessment for the early detection and treatment of diabetes should be emphasized.
Predicting the Incidence of Human Cataract through Retinal Imaging Technology
Authors: Horng Chi-Ting , Sun Han-Ying , Liu Hsiang-Jui , Lue Jiann-Hwa , Yeh Shang-Min
Published: November 2015

With the progress of science, technology and medicine, the proportion of elderly people in society has gradually increased over the years. Thus, the medical care and health issues of this population have drawn increasing attention. In particular, among the common medical problems of the elderly, the occurrence of cataracts has been widely observed. In this study, we developed retinal imaging technology by establishing a human eye module with ray tracing. Periodic hole arrays with different degrees were constructed on the anterior surface of the lens to emulate the eyesight decline caused by cataracts. Then, we successfully predicted the incidence of cataracts among people with myopia ranging from −3.0 D to −9.0 D. Results show that periodic hole arrays cause severe eyesight decline when they are centralized in the visual center. However, the wide distribution of these arrays on the anterior surface of the lens would not significantly affect one’s eyesight.
The Association between Health Behaviours and Academic Performance in Canadian Elementary School Students: A Cross-Sectional Study
Authors: McIsaac Jessie-Lee , Kirk Sara , Kuhle Stefan
Published: November 2015

Background: Establishing early healthy eating and physical activity behaviours is critical in supporting children’s long-term health and well-being. The objective of the current paper was to examine the association between health behaviours and academic performance in elementary school students in a school board in Nova Scotia, Canada. Methods: Our population-based study included students in grades 4–6 across 18 schools in a rural school board. Diet and physical activity were assessed through validated instruments. Academic performance measures were obtained from the school board for Mathematics and English Language Arts (ELA). Associations between health behaviours and academic performance were assessed using multilevel logistic regression. Results: Students with unhealthy lifestyle behaviours were more likely to have poor academic performance for both ELA and Mathematics compared to students with healthy lifestyle behaviours; associations were statistically significant for diet quality, physical activity, sugar-sweetened beverage consumption for ELA; and breakfast skipping, not being physically active at morning recess, and not being physically active after school for Mathematics. The effects of diet and physical activity were independent of each other and there was no interaction between the two exposures. Conclusions: Our findings suggest that support for healthy behaviours may help to improve academic outcomes of students.
Fast Inversion of Air-Coupled Spectral Analysis of Surface Wave (SASW) Using in situ Particle Displacement
Authors: Lu Yifeng , Cao Yinghong , McDaniel J. , Wang Ming
Published: November 2015

Spectral Analysis of Surface Wave (SASW) is widely used in nondestructive subsurface profiling for geological sites. The air-coupled SASW is an extension from conventional SASW methods by replacing ground-mounted accelerometers with non-contact microphones, which acquire a leaky surface wave instead of ground vibration. The air-coupled SASW is a good candidate for fast inspection in shallow geological studies. Especially for pavement maintenance, minimum traffic interference might be induced. One issue that restrains SASW from fast inspection is the traditional slow inversion which relies on guess-and-check iteration techniques including a forward analysis. In this article, a fast inversion analysis algorithm is proposed to estimate the shear velocity profile without performing conventional forward simulation. By investigating the attenuation of particle displacement along penetrating depths, a weighted combination relationship is derived to connect the dispersion curve with the shear velocity profile directly. Using this relationship, the shear velocity profile could be estimated from a given/measured dispersion curve. The proposed procedure allows the surface wave-based method to be fully automatic and even operated in real-time for geological site and pavement assessment. The method is verified by the forward analysis with stiffness matrix method. It is also proved by comparing with other published results using various inversion methods.
Biodistribution, Stability, and Blood Distribution of the Cell Penetrating Peptide Maurocalcine in Mice
Authors: Perret Pascale , Ahmadi Mitra , Riou Laurent , Bacot Sandrine , Pecher Julien , Poillot Cathy , Broisat Alexis , Ghezzi Catherine , De Waard Michel
Published: November 2015

Maurocalcine (MCa) is the first natural cell penetrating peptide to be discovered in animal venom. In addition to the fact that it represents a potent vector for the cell penetration of structurally diverse therapeutic compounds, MCa also displays several distinguishing features that make it a potential peptide of choice for clinical and biotechnological applications. The aim of the present study was to gain new information about the properties of MCa in vivo in order to delineate the future potential applications of this vector. For this purpose, two analogues of this peptide with (Tyr-MCa) and without (Lin-Tyr-MCa) disulfide bridges were synthesized, radiolabeled with 125I, and their in vitro stabilities were first evaluated in mouse blood. The results indicated that 125I-Tyr-MCa was stable in vitro and that the disulfide bridges conferred a competitive advantage for the stability of peptide. Following in vivo injection in mice, 125I-Tyr-MCa targeted peripheral organs with interesting quantitative differences and the main route of peptide elimination was renal.
Multi-Functional Macromers for Hydrogel Design in Biomedical Engineering and Regenerative Medicine
Authors: Hacker Michael , Nawaz Hafiz
Published: November 2015

Contemporary biomaterials are expected to provide tailored mechanical, biological and structural cues to encapsulated or invading cells in regenerative applications. In addition, the degradative properties of the material also have to be adjustable to the desired application. Oligo- or polymeric building blocks that can be further cross-linked into hydrogel networks, here addressed as macromers, appear as the prime option to assemble gels with the necessary degrees of freedom in the adjustment of the mentioned key parameters. Recent developments in the design of multi-functional macromers with two or more chemically different types of functionalities are summarized and discussed in this review illustrating recent trends in the development of advanced hydrogel building blocks for regenerative applications.
Inhibitory Effect of Gardenoside on Free Fatty Acid-Induced Steatosis in HepG2 Hepatocytes
Authors: Liang Huiqing , Zhang Limin , Wang Hongguo , Tang Jinmo , Yang Jiaen , Wu Chuncheng , Chen Shaodong
Published: November 2015

Gardenoside is one of the most important effective extractions of a herb for its hepatoprotective properties. The aim of this study was to address the mechanism of Gardenoside on HepG2 cellular steatosis induced by free fatty acids (FFAs). The model of HepG2 steatosis was duplicated by oleic and palmitic acid at the proportion of 2:1 (FFAs mixture) for 24 h, then lipid toxicity was induced. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) were used to detect cell viability and Oil Red O staining method was used to judge the lipid accumulation respectively. Inflammatory cytokines TNF-α, IL-1β, IL-6 and intracellular NFκB were measured after 24 h. The steatosis was significantly decreased after Gardenoside treatment without cytotoxicity. TNF-α, IL-1β, IL-6 were modulated to HepG2 cells by treatment of Gardenoside. In the meantime, the activation of NFκB was inhibited by Gardenoside. Gardenoside has a protective effect on FFA-induced cellular steatosis in HepG2 cells which indicates that Gardenoside might be a potential therapeutic herb against NASH by suppressed supernatant inflammatory cytokine production and intracellular NFkB activity.