bluuebunny/crossref_metadata_2025 huggingface dataset:
Conceptual Microgrid Management Framework Based on Adaptive and Autonomous Multi-Agent Systems
Authors: Lizondo Diego F. , Jimenez Victor Adrian , Araujo Pedro B. , Will Adrián
Published: April 2022

The Smart Grids paradigm emerged as a response to the need to modernize the electric grid and address problems related to the demand for better quality energy. However, there are no fully developed and implemented smart grids, but only some minor scale tests to prove the concepts. Centralized systems are still common, with a low granularity of control and reduced monitoring capacity, especially in low-voltage networks. In this work, we propose a framework for Microgrid Management, addressing problems such as determining how to control the energy demand and peak loads, the effect of the energy consumption in the network, and the amount of energy required. We proposed a solution based on autonomous and distributed systems for the following problems: Peak Load addressed with AIN-DSM distributed algorithm, transformer lifespan estimation using a thermal model adjusted by Genetic Algorithms, and Short-Term Load Forecasting based on Artificial Neural Networks and Genetic Algorithms. The distributed paradigm of the Organization Centered Multi-Agent Systems methodology was applied for the framework's modeling and development. The results obtained by using these solutions in the Tucumán province, Argentina, show the system's capabilities and the relevance of the information produced from the framework.
Fast Facial Landmark Detection and Applications: A Survey
Authors: Khabarlak Kostiantyn , Koriashkina Larysa
Published: April 2022

Dense facial landmark detection is a key element of face processing pipeline. In this paper we survey and analyze modern neural-network-based facial landmark detection algorithms, focus on approaches that have led to a significant increase in quality over the past few years on datasets with large pose and emotion variability, significant face occlusion, all of which are typical in real-world scenarios. We summarize the improvements into categories, provide quality comparison on difficult and modern in-the-wild datasets: 300 Faces in-the-wild (300W), Annotated Facial Landmarks in-the-wild (AFLW), Wider Facial Landmarks in-the-wild (WFLW), Caltech Occluded Faces in-the-wild (COFW). Additionally, we compare algorithm speed on desktop central and graphical processors, mobile devices. For completeness, we also briefly touch on established methods with open implementations available. Besides, we cover applications and vulnerabilities of the landmark detection algorithms. We hope that generalizations that we make will lead to further algorithm improvements.
Imágenes zoomorfas en diálogo
Authors: Consiglieri Nadia Mariana
Published: April 2022

Entre los siglos XI y XII, el Monasterio de Santo Domingo de Silos (Burgos, España) resultó un heterogéneo receptáculo de imágenes de temática zoomorfa. En él convivieron piezas producidas en sus propios recintos, en talleres locales y foráneos, así como aquellas procedentes de al-Ándalus. Los animales plasmados en diversos objetos y soportes dialogaron simbólicamente de manera variada y generaron tensiones discursivas e ideológicas a partir de la reapropiación del imaginario del «otro» dominado y de su recontextualización en clave cristiana. Asimismo, las diferentes materialidades puestas en juego (piedra, marfil, esmalte, temple sobre pergamino) determinaron los modos de ver y de consumir por los monjes estos entramados zoomorfos que formaron parte de la cultura visual cotidiana del monasterio.
1999 y la desautomatización del teatro platense
Authors: Guimarey María
Published: April 2022

Este artículo centra su atención en la producción concretada por Manuel Ángeles Ortiz en la Patagonia, entre 1941 y 1943, durante su exilio en la Argentina. Dentro de la misma, referiremos a las litografías que realizó para su carpeta A campo abierto (1941) y para el libro Patagonie (1942) del francés Roger Caillois, indagando en la repercusión alcanzada con ellas. Analizaremos sus Construcciones escultóricas, las que expuso durante 1943 en la Galería Müller de Buenos Aires, el mismo año en que llevó a cabo una muestra retrospectiva de dibujos en la Galería Luisa Fanning. Ambas exhibiciones fueron acompañadas por críticas y notas publicadas en el periódico Correo Literario, que los gallegos Luis Seoane, Lorenzo Varela y Arturo Cuadrado habían fundado en noviembre de ese año.
De las manos a los muros
Authors: López Galarza Clarisa
Published: April 2022

En el presente escrito abordaremos la circulación de una serie de retratos fotográficos de detenidxsdesaparecidxs chilenxs, de los que nos interesa estudiar su exhibición en contextos específicos, sus formas de mostración y modos de puesta en público. Nos detendremos en posibles significaciones y modos de socialización en un recorrido por dos momentos: su aparición en movilizaciones y publicaciones gráficas gestadas por organizaciones de derechos humanos, y su circulación en formato de exposición temporaria dentro de las salas del Museo de la Memoria y los Derechos Humanos (MMDDHH) (Santiago, Chile).
Rol de los planos cristalográficos {0001} y {0112} de la α-Fe₂O₃ en la remoción del arsénico
Authors:   , Martínez Pérez Fernanda Tonantzin
Published: April 2022

Ante la necesidad de desarrollar técnicas asequibles y eficientes para eliminar el arsénico (As) de cuerpos de agua y así proteger la salud humana, el presente trabajo es un estudio teórico que da continuidad a la investigación experimental realizada por Garay-Rodríguez en el año 2018, quien estudio la remoción de los iones As (III) y As (V) presentes en el agua para consumo humano por el proceso de adsorción, empleando como material adsorbente una zeolita natural tipo clinoptilolita del estado de Oaxaca modificada químicamente con óxidos de hierro (principalmente en su fase hematita, α-Fe₂O₃). Con el fin de crear un modelo representativo que pueda ser manipulado para mejorar la eficiencia en el proceso de remoción de contaminantes, específicamente compuestos de arsénico. La presente investigación implementa un enfoque basado en la química cuántica, donde la energía total de un sistema esta descrita como función de la densidad electrónica, para esto se utiliza la teoría de funcionales de la densidad —DFT por sus siglas en inglés— que ha demostrado ser una herramienta potente para el análisis y explicación de los resultados generados experimentalmente. La primera etapa de esta investigación abarco el estudio de las propiedades geométricas y electrónicas que surgen de la complejidad de los compuestos de óxido de hierro como material adsorbente. Resultando en que el estado magnético más estable de la α- Fe₂O₃ es el estado antiferromagnético (+ − − +) y, por lo tanto, el estado magnético de la α- Fe₂O₃ a condiciones estándar (1 atm de presión y 25 ˚C de temperatura). Por otro lado, se demostró que los planos [0001] y [0112] están presentes en el material en bulk debido a su baja diferencia energética. Finalmente, la segunda etapa consistió en un estudio de la fuerza de adsorción teórica de los iones As (III) (arsenito) y As (V) (arsenato) tanto en la superficie {0001} como la superficie {0112}, debido a que cada una de estas superficies presenta diferente reactividad en la remoción de estos contaminantes de los mantos acuíferos.
The impact of IFRS adoption on foreign direct investment in CIS
Authors: Sanjar Sherkulov , Kamrul Hasan A. K. M. , Khajieva Indira , Nusratova Gulhayo , Yodgorova Feruza
Published: April 2022

Exploring the relationship between International Financial Reporting Standards (IFRS) and Foreign Direct Investment (FDI) inflows is the main objective of this paper. Although IFRS is identified as a determinant of FDI, a few studies have examined the impact of IFRS on FDI inflows, and it is unexplored as to whether IFRS impacts CIS countries. This paper covers ten (10) IFRS adopted CIS countries from 2000 to 2019 using Ordinary Least Square (OLS) and bias-corrected Least Square Dummy Variable (LSDVC). OLS estimator shows that IFRS positively impacts FDI inflows. However, according to the results of LSDVC, there is a negative relationship between IFRS adoption and FDI inflows. Generally, in developing countries implementing IFRS would lead to FDI enhancement. The negative relationship between IFRS adoption and FDI inflows in CIS countries shows that IFRS is not an essential factor of FDI inflows.
Characterisation of Yersinia enterocolitica strains isolated from wildlife in the northwestern Italian Alps
Authors: Carella Emanuele , Romano Angelo , Domenis Lorenzo , Robetto Serena , Spedicato Raffaella , Guidetti Cristina , Pitti Monica , Orusa Riccardo
Published: April 2022

Introduction

Yersiniosis is a zoonosis causing gastroenteritis, diarrhoea, and occasionally reactive arthritis and septicaemia. Cases are often linked to meat consumption and the most common aetiological agent is the Gram-negative bacilliform Yersinia enterocolitica bacterium. The occurrence of Yersinia spp. among wild animals has mostly been studied in wild boar, but it has seldom been in other species.

Material and Methods

A total of 1,868 faecal samples from animals found dead or hunted were collected between 2015 and 2018 in the Valle d’Aosta region of the northwestern Italian Alps. Alpine ibex faecal samples were collected during a health monitoring program in 2018. Bacteria were isolated via PCR and confirmed as Y. enterocolitica biochemically. Strain antimicrobial susceptibility was tested by Kirby–Bauer disc diffusion, and the presence of virulence factors and antimicrobial resistance genes was investigated using whole-genome sequencing.

Results

Yersinia enterocolitica strains of biotype 1A were detected in six faecal samples from red deer (0.93%), roe deer (0.49%) and red foxes (0.7%). Strains found in beech martens (3.57%) and Alpine ibex (2.77%) belonged to biotypes 1B and 5, respectively and harboured the pYPTS01 plasmid that had only been detected in Y. pseudotuberculosis PB1/+. All the isolates were resistant to ampicillin and erythromycin.

Conclusion

The biovar 1A strains exhibited different virulence factors and behaved like non-pathogenic commensals. The strain from an Alpine ibex also harboured the self-transmissible pYE854 plasmid that can mobilise itself and the pYPTS01 plasmid to other strains. The beech marten could be considered a sentinel animal for Y. enterocolitica. Phenotypic resistance may account for the ability of all the strains to resist β-lactams.
PERAN MOTIVASI KERJA DALAM MEMEDIASI PENGARUH KOMPENSASI TERHADAP KINERJA KAYAWAN
Authors: Yuliantari Dewi Ni Kadek , Ardana I Komang
Published: April 2022

Kinerja karyawan merupakan hasil kerja yang dapat dicapai oleh karyawan berdasarkan kemampuan yang dimilikinya. Kinerja adalah hasil kerja nyata yang dicapai oleh karyawan dalam melaksanakan tugas yang diberikan kepadanya sesuai dengan kriteria dan tujuan yang ditetapkan oleh perusahaan. Tujuan dari penelitian ini adalah untuk menganalisis peran motivasi kerja dalam memediasi pengaruh kompensasi terhadap kinerja karyawan PT. BPR Gianyar Partasedana. Penelitian ini dilakukan di PT. BPR Gianyar Partasedana, jumlah sampel yang digunakan yaitu 44 orang karyawan dengan menggunakan sampling jenuh (sensus). Data dianalisis menggunakan teknik analisis jalur (path analysis). Pengumpulan data melalui wawancara dan penyebaran kuesioner. Hasil penelitian menunjukkan bahwa kompensasi berpengaruh positif dan signifikan terhadap kinerja karyawan pada PT. BPR Gianyar Partasedana. Kompensasi berpengaruh positif dan signifikan terhadap motivasi kerja pada PT. BPR Gianyar Partasedana. Motivasi kerja berpengaruh positif dan signifikan terhadap kinerja karyawan pada PT. BPR Gianyar Partasedana. Motivasi Kerja mampu memediasi pengaruh kompensasi terhadap kinerja karyawan pada PT. BPR Gianyar Partasedana. Implikasi dari penelitian ini adalah memberikan referensi serta informasi terkait dengan peran motivasi kerja memediasi pengaruh kompensasi terhadap kinerja karyawan. Kata kunci: Kinerja Karyawan, Kompensasi, Motivasi Kerja
PENGARUH KEADILAN ORGANISASI DAN WORK STRESS TERHADAP COUNTERPRODUCTIVE WORK BEHAVIOR
Authors: Destriana Ni Putu Eva , Dewi Sagung Kartika
Published: April 2022

This study aims to explain the influence of oeganizational justice and work stress on the phenomenon of employees counterproductive work behavior. This research was conducted at Main store of Graha Kaori Group Gianyar. The number of sampels used in this research was 52 employees, sampling is done by simple random sampling technique. Data collection method is done through the dissemination of questionnaires and interviews to nonmanajerial employees in the company. The data analysis technique used is multiple linear regression techniques. From the results of the analysis found that organizational justice and work stress have a simultaneous and significant influence on CWB. Organizational justice has a negative and significant effect on CWB. Work stress has a positive and significant effect on CWB. The company management can improve organizational justice and reduce employee work stress by improving the indicators used in this study.

Keywords: Counterproductive work behavior, Organizational justice, Work stress
PERAN MEDIASI BRAND IMAGE PADA PENGARUH GREEN MARKETING TERHADAP BRAND LOYALTY (Studi Kasus Pada Pelanggan Starbucks Di Kota Denpasar)
Authors: Keniten Adnyana Ida Bagus Rai , Santika I Wayan
Published: April 2022

Companies that produce products with environmentally friendly issues have a better imgae brand because the company is considered to care about environmental sustainability. Companies are slowly applying green marketing activities in their various projects as part of social awareness and they are required to reach consumers with green marketing messages in an effort to increase brand loyalty. One of the global companies that applies green marketing is Starbucks. The purpose of this study was to examine the role of brand image mediation on the effect of green marketing on Starbucks brand loyalty. The population in this study were all residents of the city of Denpasar who had shopped at Starbucks. In this study, the sample selection technique used purposive sampling technique with a sample size of 120 respondents. The analysis technique of this research is using descriptive analysis, path analysis and single test. The results of the analysis in this study indicate that green marketing affects brand image, green marketing affects brand loyalty, brand image affects brand loyalty, and brand image mediates the effect of green marketing on brand loyalty. This research is expected to provide empirical support and can be stated to strengthen the results of previous studies.

Keywords: Green Marketing, Brand Image and Brand Loyalty
SOCIAL ENTREPRENEURSHIP INTENTION DURING COVID-19 CRISIS AMONG UNIVERSITY STUDENTS: A CASE STUDY FROM INDONESIA
Authors: Kesumahati Erilia
Published: April 2022

The young generation as agents of change needs social entrepreneurship knowledge to create social entrepreneurship intention to solve social issues, especially during the COVID-19 pandemic. This research was conducted to examine social entrepreneurship intention among university students in Batam City, Indonesia based on the Theory of Planned Behavior (TPB) with the addition of empathy, entrepreneurship education, and COVID-19 stress perception variables to the framework. This research used the purposive sampling method through an online questionnaire that was distributed to all students of the Faculty of Economics Universitas Internasional Batam who took social entrepreneurship course. The data collected from 269 respondents were analyzed using SmartPLS version 3.0 to test the proposed hypothesis. The research result confirmed that attitude, perceived behavioral control, and empathy have significant positive relationship with social entrepreneurship intention. Entrepreneurship education and subjective norm have no significant positive relationship on social entrepreneurship intention. Meanwhile, COVID-19 stress perception was not proven to have a significant negative relationship with social entrepreneurship intention. Based on this result, universities are suggested to improve social entrepreneurship learning method so it can generate student’s interest in social entrepreneurship as an attractive career choice.

Keywords: social entrepreneurship; social entrepreneurship intention; theory of planned behavior, COVID-19.
PENGARUH BRAND IMAGE, BRAND SATISFACTION, DAN BRAND TRUST TERHADAP BRAND LOYALTY PELANGGAN SEPATU MEREK NIKE
Authors: Prawira Anak Agung Ngurah Dicky Natha , Setiawan Putu Yudi
Published: April 2022

Brand Loyalty is a measure of consumer loyalty to a brand. The factors that can affect brand loyalty include brand image, brand satisfaction, and brand trust. The purpose of this study was to see the effect of the influence of brand image, brand satisfaction, and brand trust on brand loyalty of Nike brand shoes customers in Denpasar City. This research was conducted on customers, a Nike shoe brand that is domiciled in the city of Denpasar who has bought Nike shoes more than twice. The sample size used was 110 respondents with non-probability sampling methods, especially purposive sampling. Data collection was carried out by distributing questionnaires using the google form to online respondents. The data analysis technique used is multiple linear regression analysis. The results showed that (1) brand image has a positive and significant effect on brand loyalty with a significance value of 0.001 (2) brand satisfaction has a positive and significant effect on brand loyalty with a significance value of 0.001 (3) brand trust has no positive and significant effect on brand loyalty. a significance value of 0.532. Based on the results of this study, it can add evidence related to research variables that can assess the results of previous research.

Keyword: Brand image, Brand satisfaction, Brand trust, Brand loyalty
BAGAIMANA HARGA GANJIL MEMBANTU ANDA MEMANFAATKAN KEKUATAN PSIKOLOGI
Authors: Lopes Amaral Maria Augustin , Goetha Selfiana , Tisu Rosadalima
Published: April 2022

Price is one of the important points in marketing as well as in creating customer value. Odd prices.are..one of the strategies made by companies to form the impression of low prices in the minds of consumers. The goal of this study is to understand the relationship between odd prices and consumer involvement in purchase intentions. Non-random sampling (convenience sampling) was used in this study for data collection. The respondents numbered 112 people who were in Kupang. Questionnaires were disseminated to customers who used shopee (Flash sale product) in Kupang. The research method is a survey and outcome were analyzed and interpreted using Structure Equation Modeling (SEM). The relationship between odd prices, customer involvement shows positive influence on each other.

Keywords: Odd price, consumer involvement, purchase intention
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI PEMILIHAN KARIER PADA ALUMNI STMIK AMIKOM SURAKARTA
Authors: Lashwaty Nina Dewi , Nurhidayanto Nurhidayanto
Published: April 2022

This research was conducted to find out the impact of labor market consideration, financial rewards, family expectation, job intrinsic values, work environment, and work motivation towards the alumni career choice of STMIK AMIKOM Surakarta. The samples were alumni of STMIK AMIKOM Surakarta. The research data were primer, by distributing questionnaires. The validity and reliability test applied to the instrument were inferred valid and reliable. The Multiple Linear Regression Analysis done yielded that labor market consideration, family expectation, work environment and work motivation positively influenced the alumni career choice of STMIK AMIKOM Surakarta, otherwise financial rewards and job intrinsic values negatively influenced. F-test value showed that labor market consideration, financial rewards, family expectation, job intrinsic values, work environment, and work motivation simultaneously influenced the alumni career choice of STMIK AMIKOM Surakarta. T-test value showed that partially family expectation had the most significant influence towards alumni career choice of STMIK AMIKOM Surakarta.

Keywords: Career; Financial; Family; Environment; Motivation
PENGARUH PROMOSI DAN KEMASAN TERHADAP KEPUTUSAN PEMBELIAN YANG DIMEDIASI OLEH BRAND AWARENESS (Studi pada konsumen Bali Square Pie di Kabupaten Badung)
Authors: Jayadi Febe Vanesamay , Wardana I Made
Published: April 2022

This aims of  this research are to determine the effect of promotion and packaging on purchase decision, the effect of promotion and packaging on brand awareness, the effect of brand awareness on purchase decision, and mediating effect of band awareness. The research was done on customers of Bali Square Pie. The sample’s used were 100 respondents that was chosen by purposive sampling method. Data collection is done by distributing quetionnaires. The technique for analyzing the data is using path analysis with SPSS. The result of this research  indicated that promotion and packaging has positive significant effect on purchase decision, promotion and packaging has positive significant effect on brand awareness, brand awareness has positive significant effect on purchase decision, and also the effect of promotion and packaging on purchase decision is madiated by brand awareness. In orded to increase purchase decision of Bali Square Pie consumers in Badung Districs, Bali. The owner of Bali Square Pie is able to continuously doing innovations, by prioritizing promotional excellence, packaging excellence, and the company success in creating brand awareness among its consumers.

Keywords: promotion, packaging, purchase decision, brand awareness
PERAN INOVASI MEMEDIASI PENGARUH ORIENTASI PASAR TERHADAP KINERJA BISNIS UMKM SONGKET
Authors: Antari Ni Kadek Weni , Widagda K I Gusti Ngurah Jaya Agung
Published: April 2022

This study aims to test the hypothesis that explains the relationship between business performance variables that are influenced by market orientation and mediated by innovation in Songket SMEs in Sidemen Karangasem. The number of samples in this study amounted to 64 units of MSME Songket. The method used in determining the sample in this study is a saturated sampling technique (census). Data collection methods used in this study were interviews and surveys conducted by distributing questionnaires. This study uses a PLS (Partial Least Square)-based SEM (Structural Equation Model)-based structural equation model. The results show that market orientation has a positive and significant effect on business performance, market orientation has a positive and significant effect on innovation, innovation has a positive and significant effect on business performance and innovation mediates the effect of market orientation on business performance significantly.

Keywords: Market Orientation, Innovation, Business Performance, MSME
PENGARUH KEPERCAYAAN MEREK DAN KUALITAS PELAYANAN TERHADAP LOYALITAS PELANGGAN MELALUI MEDIASI PERSEPSI NILAI PELANGGAN
Authors: Dhirtya Desak Ayu Made Citta , Warmika I Gede Ketut
Published: April 2022

The purpose of this study was to analyze the effect of brand trust, service quality and customer value perception on customer loyalty on the Bukalapak site, to analyze the influence of brand trust and service quality on customer value perception on the Bukalapak site, and to analyze the effect of customer value perception mediating brand trust and quality of service to customer loyalty on the Bukalapak site. The population in this study are social media users who make online transactions on the Bukalapak site with certain considerations. The sample is determined by the non probability sampling technique, which is 150 respondents. The data collection method uses a questionnaire. The data analysis technique used in this study is Path Analysis. The results showed that brand trust, service quality and customer value perceptions had a positive and significant effect on customer loyalty. The results showed brand trust and service quality had a positive and significant effect on customer value perception. The results also indicate the perception of customer value is able to mediate the influence of brand trust and service quality on customer loyalty.

Keywords: brand trust, service quality, customer value, customer loyalty
Translation as a form of dialogue: artistic translations by V. Narbut and M. Zenkevich
Authors: Temirshina Olesya Ravil'evna , Ustinovskaya Alena Aleksandrovna , Pogodina Yuliya Yur'evna
Published: April 2022

The subject of the study is the mechanisms of semiotic development of aesthetic systems by acmeists of the "left wing" in the act of literary translation. The main hypothesis of the work is that the poetics of Narbut and Zenkevich seriously influenced the specifics of their translation activities, leading to the projection of semantic motif-figurative structures into the semantic space of translated texts. The work uses a linguosemiotic methodology, which, firstly, assumes an understanding of translation in the pragmatic and communicative aspect as an act of aesthetic communication, and secondly, allows to identify a system of semantic correlations between different texts based on the philosophical and aesthetic base of Acmeist poets. The novelty of the work lies in the fact that the article for the first time analyzes Narbut's translations in projection on the specifics of his military revolutionary poetry and reveals the mechanisms of "semantic narrowing" of the physiological theme in Zenkevich's translations (in comparison with his lyrics). In conclusions of the study the author establishes a number of patterns of translation activity of Narbut and Zenkevich. Thus, the work shows that a semantic pattern is formed in the military revolutionary lyrics of Narbut, which includes an apocalyptic myth, the motive of the ascension /ascension, performative structures, national toponymy. This semantic complex with all its elements is also represented in Narbut translations, which allows us to conclude that Narbut uses a direct projection strategy in his translation activities. Zenkevich's translations, correlated with the theme of war, are based on a fundamentally different model. Zenkevich's aesthetic-poetic system is much more ambitious in its philosophical scope than the translated texts themselves, which leads to a strategy of "semantic narrowing" of physiological "acmeistic" themes.
Archetypal Aspects of a Person's Life Scenario
Authors: Skleynis Viktor Aleksandrovich
Published: April 2022

The subject of this study is the correlation of the type of life scenario of the individual on the one hand and the components of the personality on the other. The aim of the research is to analyze the relationship between archetypal structures of the personality and his/hers life scenario. Considering the life scenario of the person and archetypal structures of his/her personality as components of the outlook, projected at the level of semantics in the form of attitudes to individual objects, situations and time intervals, the author compares the type of life scenario of the person on the one hand and the categorical axes of the archetypal space on the other. The scientific novelty of the research consists in the fact that within the framework of this work, for the first time, the relationship between the types of the life scenario of the individual and the components of his/her archetypal space is empirically investigated. In addition, the novelty of the study lies in the fact that archetypal structures and the life scenario of a personality are considered in the framework of this study from the standpoint of the psychology of subjective semantics and are described as deep semantic structures that manifest themselves at the level of surface structures in the processes of meaning formation. In the course of the study, statistically significant data were obtained, indicating the presence of the conjugacy of the axes of the archetypal space and the type of life scenario of the individual
Uma análise acerca das características das coagulopatias na Covid-19: revisão de literatura
Authors: Carvalho Déborah Batista , Ferreira Victor Lucas , Silva Cassandra Mendes Assunção e , Silva Júlia Alonso Lago , Augusto Mateus Facklam , Silva Rhuan Victor Moreira da , Lacerda Filho Sérgio Luciano da Silva , Goulart Thaíssa de Lima , Fonseca Isabelle Félix , Figueiredo Júnior Hélcio Serpa de
Published: April 2022

Objetivo: Analisar as características das coagulopatias associadas à infecção pelo novo coronavírus. Revisão bibliográfica: Com o avanço da doença percebeu-se que além de afetar o pulmão essa infecção também poderia predestinar doenças trombolíticas devido à alta capacidade inflamatória e desordem homeostática, estresse oxidativo endotelial causado por hipóxia e coagulação intravascular disseminada.  A infecção é marcada pelo aumento do D-dímero. Além disso, os pacientes apresentaram altos índices de citocinas pró-inflamatórias no sistema circulatório, como as interleucinas 1 e 6 e Fator de Necrose Tumoral (TNF), formando o conceito de tempestade de citocinas que causa uma grande lesão endotelial. Considerações finais: Em virtude da atual pandemia de Covid-19, tornou-se essencial o estudo de sua fisiopatologia e de suas complicações, sendo uma das mais importantes os eventos tromboembólicos que decorrem da ativação do sistema imune e da tempestade de citocinas que causa uma inflamação do endotélio e um estado de hipercoagulabildade. Nesse sentido, é importante que o tratamento dos doentes seja avaliado individualmente nessa situação, ponderando o risco benefício da anticoagulação profilática além da avaliação clínica bem-feita de modo a reduzir a morbimortalidade por essa condição.
The relationship between Thiol/disulfide homeostasis and endometrial hyperplasia in patients with abnormal uterine bleeding/
Authors: ERTÜRK AKSAKAL Sezin , DİKTAŞ Elif Gülşah , PAY Ramazan Erda , TAPISIZ Ömer Lütfi , TİMUR Burcu , KORKMAZ Vakkas , EREL Özcan , ÜSTÜN Yaprak
Published: April 2022

Introduction: The role of oxidative stress and antioxidant capacity in the development of endometrial hyperplasia (EH) is controversial. Aim: The study aimed to evaluate Thiol/disulfide Homeostasis and ischemia modified albumin (IMA) levels in patients with EH without atypia. Materials and Methods: In this prospective case-control study, patients with EH without atypia (HP group) (n=28), patients with nonhyperplasia (proliferative/secretory/irregular proliferative/irregular secretory endometrium) (non-HP group) (n=28), and 28 healthy women (control group) were included. The patient's clinical characteristics, serum Thiol/disulfide parameters, and IMA levels were compared between groups. Results: A total of 84 patients were included in the study. Patients’ mean age, BMI, and mean native thiol (-SH-), total thiol (-SH-+-SS-), disulfide (-SS-), and IMA levels were similar among the three groups. The -SS- /-SH- ratio was higher in the HP group than the non-HP group. -SS- /-SH-+-SS- ratio was higher in the HP group vs. the other two groups. The -SS- /-SH-+-SS ratio was higher in the HP group vs. the non-HP group. -SH-/ -SH-+-SS- ratio was lower in the HP group than in the non-HP group. ET was greater in the HP group than in the non-HP and control groups. ET was also significantly greater in the non-HP group vs. in the control group. -SS-/-SH- ratio was found to be predictive with 64% sensitivity and 68% specificity for EH (area under curve = 0.672, p = 0.01). Conclusion and Suggestions: The dynamic thiol/disulfide balance shifted to the disulfide side in women with endometrial hyperplasia.
Predictive modeling of the potential of gold mineralization by means of GIS (on the example of the Iengra - Timpton interfluve, South Yakutia)
Authors: ЛОСКУТОВ Е.Е.
Published: April 2022

Поиски и разведка полезных ископаемых требует надежных прогнозных моделей, которые помогут повысить, вероятность обнаружения месторождений полезных ископаемых на определенной местности. В настоящее время значительная часть месторождений полезных ископаемых, расположенных у поверхности уже найдена. Вследствие этого новые принципы поиска заметно усложняются, что требует применения более сложных методов анализа пространственных данных. Современные ГИС позволяют производить анализ и интеграцию геопространственной информации из разных источников. В данной работе произведен анализ геологических, геохимических и геофизических данных на примере рудного района расположенного в междуречье рек Иенгра и Тимптон. Для установления закономерностей размещения золоторудной минерализации выполнен анализ строения геохимических (Ag, Pb, Cu, Mo, Zn) и геофизических полей (магнитное поле и градиент магнитного поля). Охарактеризованы особенности магнитного поля и геохимических полей меди, цинка, серебра, молибдена и свинца. На основе статистического подхода проведена обработка и интерпретация геохимических и геофизических данных с помощью программного обеспечения ArcGIS. Статистический анализ аномалий показывает, что для выделения участков, благоприятных для локализации золотого оруденения по геохимическим и геофизическим данным, оптимальными интервалами являются следующие: геохимическое поле молибдена 1,38 – 2,65 вес. %; геохимическое поле серебра 1,5 – 4,14 вес. %; геохимическое поле меди 1,53 – 7,15 вес. %; геохимическое поле цинка 6,15 – 11,3; геохимическое поле свинца 1,0 – 2,2; магнитное поле -5,0 – 5,5 у.е.; градиент магнитного поля 0,01 – 0,35 град. Полученные данные могут быть использованы при дальнейших геологоразведочных работах.
An Extra-Large Pore Zeolite Enabled by 1D-to-3D Topotactic Condensation
Authors: Li Jian , Gao Zihao Rei , Lin Qing-Fang , Liu Chenxu , Gao Fangxin , Lin Cong , Zhang Siyao , Deng Hua , Mayoral Alvaro , Fan Wei , Luo Song , Chen Xiaobo , Camblor Miguel A. , Chen Fei-Jian , Yu Jihong
Published: April 2022

Zeolites are microporous silicates that find an ample variety of applications as catalysts, adsorbents, and cation exchangers. Natural and synthetic zeolites possess a fully connected three-dimensional network of corner-sharing SiO4 tetrahedra (i.e. they are tectosilicates or framework silicates, with Si occasionally substituted by other atoms). Stable silica-based zeolites with increased porosity are of interest to allow processing of large molecules, but challenge our synthetic ability. Here we report a novel zeolite, ZEO-3, with a multidimensional, interconnected system of extra-large pores open through windows made by 16 and 14 SiO4 tetrahedra, which, with a specific surface area of over 1000 m2/g and an extraordinary performance for Volatile Organic Compounds abatement, is the less dense polymorph of silica known so far. This zeolite, however, is not directly synthesized as a tectosilicate but is the first three-dimensional zeolite that is obtained by topotactic condensation from a one-dimensional chain silicate (inosilicate, ZEO-2), a process that bears a 17% contraction of the structure but that does not alter the topology of the chain silicate (hence the term “topotactic”). This discovery challenges concepts deeply-rooted into zeolite science, and opens up the possibility of chain silicates as precursors for the crystallization of zeolites.
Quick and Efficient Quantitative Predictions of Androgen Receptor Binding Affinity for Screening Endocrine Disruptor Chemicals Using 2D-QSAR and Chemical Read-Across
Authors: Banerjee Arkaprava , De Priyanka , Kumar Vinay , Kar Supratik , Roy Kunal
Published: April 2022

Endocrine Disruptor Chemicals are synthetic or natural molecules in the environment that promote adverse modifications of endogenous hormone regulation in humans and/or in animals. In the present research, we have applied two-dimensional quantitative structure-activity relationship (2D-QSAR) modeling to analyze the structural features of these chemicals responsible for binding to the androgen receptors (logRBA) in rats. We have collected the receptor binding data from the EDKB database (https://www.fda.gov/science-research/endocrine-disruptor-knowledge-base/accessing-edkb-database) and then employed the DTC-QSAR tool, available from https://dtclab.webs.com/software-tools, for dataset division, feature selection, and model development. The final partial least squares was evaluated using various stringent validation criteria. From the model, we interpreted that hydrophobicity, steroidal nucleus, bulkiness and a hyrdrogen bond donor at an appropriate position contribute to the receptor binding affinity, while presence of electron rich features like aromaticity and polar groups decrease the receptor binding affinity. Additionally we have also performed chemical Read-Across predictions using Read-Across-v3.1 available from https://sites.google.com/jadavpuruniversity.in/dtc-lab-software/home, and the results for the external validation metrics were found to be better than the QSAR-derived predictions. To explore the essential features responsible for the receptor binding, pharmacophore mapping, molecular docking along with molecular dynamics simulation were also performed, and the results are in accordance with the QSAR findings.
Unified Synthesis of Multiply Arylated Alkanes by Catalytic Deoxygenative Transformation of Diarylketones
Authors: Kurosawa Miki B , Kato Kenta , Muto Kei , Yamaguchi Junichiro
Published: April 2022

A deoxygenative transformation of diarylketones leading to multiply arylated alkanes was developed. Diarylketones were reacted with di-phenylphosphine oxide resulting in a phospha-Brook rearrangement, followed by palladium-catalyzed cross-couplings or a Friedel–Crafts type alkylation to afford the corresponding multiply arylated alkanes. A variety of diarylketones can be converted to multiply arylated alkanes such as diarylmethanes, tetraarylethanes, and triarylmethanes by reduction, dimerization, and arylation in one pot. Furthermore, a one-pot conversion from arylcarboxylic acids to diarylmethanes and tetraarylethanes, and a synthesis of tetraarylmethane and tri-phenylethane using sequential coupling reactions are also presented.
Shapeshifting Antibiotics: Bullvalene Linked Vancomycin Dimers are Effective Against Multidrug-Resistant Gram-Positive Bacteria
Authors: Ottonello Alessandra , Wyllie Jessica A. , Yahiaoui Oussama , Murray Ewan , Williams Paul , Bolla Jani R. , Robinson Carol V. , Fallon Thomas , Soares da Costa Tatiana P. , Moses John E.
Published: April 2022

The alarming rise in superbugs that are resistant to drugs of last resort, including vancomycin-resistant enterococci and staphylococci, has become a significant global health hazard. Here we report the click chemistry synthesis of an unprecedented class of shapeshifting vancomycin dimers (SVDs) that display potent activity against bacteria that are resistant to the parent drug, including the ESKAPE pathogens, vancomycin-resistant Enterococcus (VRE), methicillin-resistant Staphylococcus aureus (MRSA) as well as vancomycin-resistant S. aureus (VRSA). The shapeshifting modality of the dimers is powered by a click-linked bullvalene core, hence exploiting the dynamic covalent rearrangements of the ﬂuxional carbon cage and creating ligands with the capacity to inhibit bacterial cell wall biosynthesis. The new shapeshifting antibiotics are not disadvantaged by the common mechanism of vancomycin resistance resulting from the alteration of the C-terminal dipeptide with the corresponding D-Ala-D-Lac depsipeptide. Further, evidence suggests that the shapeshifting ligands destabilize the complex formed between the flippase MurJ and lipid II, inferring the potential for a new mode of action for polyvalent glycopeptides. The SVDs show little propensity for acquired resistance by enterococci, suggesting that this new class of shapeshifting antibiotic will display durable antimicrobial activity not prone to rapidly acquired clinical resistance.
Stimuli-responsive Enaminitrile Molecular Switches as Tunable AIEgens Covering the Chromaticity Space and Acting as Vapor Sensors
Authors: Ren Yansong , Kravchenko Alexander , Xie Sheng , Svensson Grape Erik , Yang Zhen , Inge A. Ken , Yan Mingdi , Ramstrom Olof
Published: April 2022

A family of responsive enaminitrile molecular switches showing tunable turn-on fluorescence upon switching and aggregation is reported. When activated by the addition of acid/base, isomerization around the C=C bond could be effectuated, resulting in complete and reversible switching to the E- or Z-isomers. Typical aggregation-induced emission (AIE) could be recorded for one specific state of the different switches. By subtle tailoring of the parent structure, a series of compounds with emission covering almost the full visible color range were obtained. The switchable AIE features of the enaminitrile structures enabled their demonstration as solid-state chemosensors to detect acidic and basic vapors, where the emission displayed an “off-on-off” effect. Single-crystal X-ray diffraction measurements and DFT calculations suggested a luminescence mechanism based on restriction of intramolecular rotation and an intramolecular charge transfer effect in the AIE luminogens.
Preprints in chemistry: a research team’s journey
Authors: Ciriminna Rosaria , Pagliaro Mario
Published: April 2022

The benefits of publishing research papers first in preprint form are substantial and long-lasting also in chemistry. Recounting the outcomes of our team’s nearly six-year journey through preprint publishing, we show evidence of how preprinting research findings and new ideas substantially benefits both early career and senior researchers in the chemical sciences.
SISTEM AKUNTANSI PEMBELIAN BARANG DAGANGAN PADA KOPERASI PEGAWAI NEGERI-KOPERASI DEPARTEMENT AGAMA PANGKAT (KPN-KOPDAP)
Authors: Zulkifli Zulkifli , Nuhung Mahmud
Published: April 2022

The results of the research obtained include exposure to the elements contained in the accounting system for purchasing merchandise, related functions, documents used, accounting records used, and the methods used in the accounting system for purchasing merchandise at the Cooperative. Civil Servants - Cooperatives Department of Religion Pangkep (KPN-KOPDAP). From the results of the study, conclusions can be drawn on the Civil Servant Cooperative - Pangkep Department of Religion Cooperative (KPN-KOPDAP), there are several elements contained therein: 1) Purchase Request, 2) Price Bid Request, 3) Purchase Order, 4) Goods Receipt , 5) Debt Registrar. Civil Servants Cooperative - Pangkep Religion Department Cooperative (KPN-KOPDAP) also has two types of credit purchase systems, namely: 1) Shop Order, 2) Salesman Canvas.
KONSISTENSI, AKUNTABILITAS DAN TRANSPARANSI PENGELOLAAN KEUANGAN MASJID AL MARKAS AL-ISLAMI BERDASARKAN PSAK 109
Authors: Amir Adriani , Nuhung Mahmud
Published: April 2022

The study is aimed at the consisteny, accountability and transparancy of the financial management at Al-Markaz Al Islami Mosque based on PSAK 109, the type of research used in this study is quantitave descriptive research. Process Data is Data obtained from interviews and 2017 financial statements. Data collection technique usedin this study are documentation, field observations and interviews. Based on the result of this study it can be concluded that the Al-Markaz Al Islami Mousque has been open and responsible for managing mosque finance because according to them the financial statements made are a mandate from pilgrims who need to be managed properly. PSAK No. 109 has not been applied in presenting the current financial statements. Financial records are also still based on cash basis, namely recording transactions based on a cash in and cash out.
ANALISIS PELAKSANAAN RAHN DALAM GADAI SAWAH DI DESA SALOHE KECAMATAN SINJAI TIMUR KABUPATEN SINJAI
Authors: M Rahmaniar , Khalid Idham
Published: April 2022

The pawn contract practice conducted by the community in Salohe Village, East Sinjai District, Sinjai Regency is a rice field pawning. This research is focused to further study whether the practice of paddy pawning which has been carried out by the people of Salohe Village is in accordance with the Shariah economic principles. The problems studied are focused on the understanding of the people of Salohe Village regarding the implementation of paddy pawning and the application of Sharia principles in the implementation of paddy pawning in Salohe Village, East Sinjai District, Sinjai Regency. The method in this research is a qualitative approach. With the data source used is prime data, secondary data and informant data. Data collection uses observation, interviews and documentation. To analyze data, researchers used Data Reduction, Data Presentation and Conclusion Drawing / verification. The results obtained from this study of the implementation of paddy pawning in Salohe Village, Sinjai Timur District, Sinjai Regency were done long ago because of very urgent needs. The pawn process is only done verbally, namely the pawners (rahin) come to the murtahin to offer their fields to be pawned with the intention of obtaining some money. The power / use of rice fields is in the hands of the pawning recipient (murtahin) until the repayment of debt. Generally done interpersonal, which is inseparable from the spirit please help. However, the majority of them do not understand the pawn rules in Islam.
PRINSIP-PRINSIP DASAR EKONOMI ISLAM DALAM BISNIS
Authors: Rahmah Syahidah
Published: April 2022

This research aims to look at the concepts of Islamic ethics and basic principles (basic principles) which are based on the values of the Koran which are directed to raise moral values related to the prevention of actions that are not in accordance with the teachings of Islamic law. Using qualitative research methods with data analysis techniques for results and discussion using library research (Library Research) by collecting, reading and browsing a number of books that are used as references. The results show that some of the right concepts to be used in Islamic business ethics to raise moral values according to the teachings of Islamic law are to understand very well the concepts of property and ownership, the concept of wealth distribution, the concept of work and business, and the concept of Halal and Haram
STANDAR DAN EFEKTIVITAS PENGUPAHAN DALAM MENINGKATKAN KESEJAHTERAAN KARYAWAN PERSPEKTIF EKONOMI ISLAM (Studi Kasus Rumah Bersalin Siti Khadijah 1 Kota Makassar)
Authors: Suarni Agusdiwana , Suandi Ervin
Published: April 2022

This study aims to determine the standard and effectiveness of wages in improving employee welfare in an Islamic economic perspective. The type of research used is descriptive qualitative. The results obtained in this study are wage standards at RSIA. Sitti Khadijah was based on standards set by the company based on an assessment of the circumstances and living needs of employees and it was evident from the results of interviews conducted with several relevant informants who said that the determination of wage standards was based on company standards, and which became the benchmark the standard of remuneration is the UMP as a legal basis in paying employees. While the effectiveness of wages is not yet very effective and is still in the stage of effectiveness.in the application of future wage hopefully in effect again and form regulations that regulate both the question of effectiveness in the method of employee wageization so that the welfare of employees can be fulfilled moril or materially
UPAYA PENINGKATAN AKUNTANSI PENJUALAN MELALUI MOTIVASI KERJA KARYAWAN
Authors: Soraya Zalkha , Adiningrat Andi Arifwangsa , Andayaningsih Sri , Rahmansyah Rahmansyah
Published: April 2022

The purpose of this study was to determine efforts to increase sales accounting through employee work motivation. Data in this study, carried out at PT. Megahputra Sejahtera Main Mobil Suzuki Gowa. This study uses a saturated sampling technique. the sample used was 38 people. Data analysis method used is central tendency and analysis statistic descriptive The results of this study indicate that employee motivation is related to sales accounting variables, this means that an employee with good communication tries to be motivated to improve sales accounting by efforts to improve product quality and competitive prices