bluuebunny/crossref_metadata_2025 huggingface dataset:
Central Nervous System-related Conditions and Associated Healthcare Resource Use Among Japanese nmCRPC Patients Based on Retrospective Claims Data
Authors: Ledesma Dianne , Chua Jonathan , Tang Susan , Lim Xiu
Published: October 2023

Background: Japanese patients with prostate cancer are typically treated with primary androgen deprivation therapy (ADT), most commonly administered as a combination of a luteinizing hormone-releasing hormone (LHRH) agonist and an antiandrogen (AA). Since LHRH agonists and AA therapy can be maintained for several years, the long-term effects of these treatments on patients must be carefully considered, including the risk of concomitant central nervous system (CNS) conditions which could affect treatment choices. Objective: To describe CNS-related concomitant conditions during ADT and/or AA treatment and the subsequent healthcare resource utilization in Japanese nonmetastatic castration-resistant prostate cancer (nmCRPC) patients. Methods: Patients diagnosed with nmCRPC and CNS-related conditions while on ADT and/or AA therapy between April 2009 and August 2017 were retrospectively followed up for a maximum of 2 years using a claims database. Results: A total of 455 patients (average age, 78.5 years), were included. The 3 most common concomitant CNS-related conditions were pain (~60% of events), insomnia (~30%), and headache (2%-3%). The frequency of CNS-related conditions in these patients increased approximately threefold after starting AA therapy (before, 969 events; after, 2802). On average, a patient had 10 episodes of concomitant CNS-related conditions in a year. Medical costs did not significantly increase due to CNS-related conditions. Discussion: The most frequently reported CNS-related conditions were pain, insomnia, and headaches. Furthermore, more concomitant CNS-related conditions 1 year after CRPC diagnosis and 1 year after starting AA treatment were recorded. Conclusion: Patients with nmCRPC experience an increase in the frequency of concomitant CNS-related conditions, including pain, insomnia, and headaches, after CRPC diagnosis or starting AA treatment. Future research should explore the causes of this increased frequency.
Influência do sombreamento no desenvolvimento forrageiro em sistema de integração lavoura-pecuária-floresta
Authors: Magalhães Angelo Ferreira , Backes Clarice , Silva Larissa Luz da , Lopes Luciana Christina Alves , Amaro Bezerra Stephanie Ingrid
Published: October 2023

A Integração Lavoura-Pecuária-Floresta (ILPF) é uma estratégia de produção sustentável, onde há o cultivo de espécies agrícolas, florestais e/ou pecuária em uma mesma área, gerando sinergia entre os componentes. O Brasil possui vários fatores que beneficiam a implantação de sistemas integrados, como, condições edafoclimáticas favoráveis, área disponível, e perfil para produção agropecuária. Dentre as espécies mais utilizadas como componente arbóreo na ILPF, o eucalipto se destaca pelo rápido crescimento, boa adaptação as condições de solo e clima do Brasil, bom valor de mercado, baixo custo de implantação e facilidade de aquisição de mudas. O componente agrícola representa forma de diversificação da produção área na forma de grãos e/ou silagem, além de proporcionar a recuperação e/ou conservação do solo, uma vez que a área deverá ser mecanicamente e quimicamente preparada para implantação das culturas, além de contribuir com fornecimento de matéria orgânica para o solo e viabilizar a implantação da forrageira através do sistema de plantio direto. As forrageiras do gênero Brachiaria syn. Urochloa são adaptadas a maioria dos solos do bioma Cerrado, apresentando boa produção de massa seca e valor nutritivo, facilidade de aquisição de sementes, e resistência a cigarrinha das pastagens, já sendo utilizada por grande parte dos produtores rurais. No entanto, um dos grandes desafios da ILPF, é manter a produtividade da pastagem ao longo dos anos após o plantio com o avanço da idade das árvores e consequentemente aumento do nível de sombreamento. O nível de sombreamento ocasionado pelas árvores, que está relacionado com a quantidade e qualidade da luz que chega no sub-bosque e pode impactar na produtividade da forrageira cultivada no sub-bosque. Diante disso, objetiva-se descrever sobre o desenvolvimento forrageiro de Urochloa brizantha cultivar Marandu em sistemas de ILPF e suas alterações em diferentes modelos propostos.
O papel do médico veterinário frente a saúde única – uma revisão
Authors: Beckman Taina Oliveira , De Souza Caio Cezar Nogueira , Do Nascimento Karine Louise Almeida , Andrade Junior Walbe Aldemir de Souza , Da Silva Raphaeli Crhistini Vale , Rocha Isadora Matias , Sampaio Isabela Menezes , Ferreira Ana Paula Reis , Araújo Thaize da Fonseca
Published: October 2023

O conceito de One  Health (saúde única) surge com a premissa de buscar discutir de forma mais abrangente aspectos inseparáveis entre a saúde humana, animal e ambiental., sendo o Médico Veterinário capacitado para atuar nas três áreas sendo considerado pelo Sistema Único de Saúde como profissional de saúde. Diante disso, o objetivo desse estudo é evidenciar por meio de estudos presentes na literatura  a atuação do Médico Veterinário na saúde única. Dessa forma, pode-se observar a importância da Medicina Veterinária na saúde coletiva e as diversas medidas que são tomadas por profissionais de saúde para garantira qualidade de vida da população humana e animal e a preservação do meio ambiente.
O ensino de Ciências na educação do campo: particularidades na formação profissional em Agroecologia
Authors: Zaratim Karina Pinheiro , Pimentel Ana Paula Pinheiro Zaratim , Maia Ana Heloisa
Published: October 2023

A abordagem no ensino de Ciências na educação do campo alinha-se com uma formação baseada nos princípios da agroecologia, que inclui a orientação dos indivíduos na construção do conhecimento, a partir de uma visão holística e de acordo com a realidade das comunidades. O presente artigo busca, a partir de uma revisão sistemática da literatura nas bases de bases de dados: SciELO, Web of Science, Biblioteca Digital de Teses e Dissertações, Educational Resources Information Center e Revista Brasileira de Educação do Campo, apresentar um panorama sobre a realidade dos estudos sobre o ensino de Ciências em cursos técnicos de Agroecologia na educação do campo, visando sintetizar os aspectos relevantes, bem como identificar as lacunas existentes para aprofundamento nesta temática. A partir da revisão sistemática e análise documental realizadas, dos 280 trabalhos identificou-se poucos estudos (07) sobre assunto. Assegurar um ensino básico e de qualidade longe dos moldes apenas tecnicistas impostos à educação profissional é um desafio, onde é necessário estabelecer estratégias que sejam incorporadas à construção dos currículos dos cursos, que garantam o acesso a formação agroecológica e a permanência dos camponeses nos territórios.
СУЩНОСТЬ И ЗАДАЧИ АПЕЛЛЯЦИОННОГО ПРОИЗВОДСТВА В СОВРЕМЕННОМ УГОЛОВНОМ СУДОПРОИЗВОДСТВЕ
Authors: Мальцагов И.Д. , Гельдибаев М.Х. , Кириллова Т.К.
Published: October 2023

Апелляционное производство – самостоятельная стадия уголовного процесса, в рамках которой осуществляется пересмотр вышестоящим судом по жалобам сторон о не вступивших в законную силу судебных решений путем нового разбирательства дела по существу, то есть как по юридическим, так и фактическим основаниям. Апелляционные суды имеют основной собственной функцией исправление ошибок, допущенных судом пер-вой инстанции, им предоставлен широкий круг средств, позволяющих проверять и исследовать доказательства, выносить решения по итогам проведенного разбирательства. Указывается, что допущенные судебные ошибки в уголовном судопроизводстве, их раскрытие и устранение в законном порядке реализуются через апелляционное судопроизводство в процессе пересмотра решений суда. Пересмотр судебных решений, а имен-но обжалование решений необходимо для того, чтобы гарантировать соблюдение прав и законных интересов всех участников уголовного судопроизводства.
В данной статье автор поэтапно охарактеризовывает изменения в данной области права, пути и возможные варианты решения проблемных аспектов в контексте правового регулирования деятельности апелляционного суда.
ANALISIS KINERJA FINANSIAL LEMBAGA KEUANGAN MIKRO AGRIBISNIS PADA PAGUYUBAN PETANI ALBAROKAH DESA KETAPANG, SUSU
Authors: Fariastuti Mefi Fariastuti , Ekowati Titik , Prastiwi Wahyu Dyah
Published: October 2023

The success measurement of a financial institution can be seen from the number of its members necessity are being met and its financial performance. One of the problems that makes it difficult for cooperatives to develop is financial management. The research aimed to 1). To find out the role of the Gardu Tani Multi-stakeholder Cooperative in helping farmers to access their farming needs, 2). Compare the financial performance of the Gardu Tani Multi-stakeholder Cooperative before and during the Covid-19 pandemic. The research was conducted in January – February 2022 at the Gardu Tani Multi-stakeholder Cooperative. The survey method is research carried out using questionnaires as a research tool taken from samples in a population. The data used is primary data obtained from interviews with respondents and secondary data obtained from books, journals and previous reports. Data were analysed using financial ratio analysis. Independent sample t test was conducted to test the hypothesis of the second research goals. The results are based first object showed that the role of the Gardu Tani Multi-stakeholder Cooperative in helping farmers are as followed: as a provider of production inputs; provider of agricultural equipment; provider of agricultural information, financing farming business, marketer, and promotion agent as well as money saving activities. Financial performance based on liquidity and solvency ratios were found in good criteria. Meanwhile, rentability ratios were found in poor criteria. The results of the independent sample t test on the current ratio, solvability ratios and rentability ratios showed there are no differences in financial performance before and during the Covid-19 pandemic. Furthermore, the result of the Mann-Whitney test on the quick ratio also found there are no differences in financial performance before and during the Covid-19 pandemic
Apakah Produk Bank Syariah Indonesia Menarik Minat Masyarakat?
Authors: Nurhayati Nurhayati , Astaginy Niar , Ismanto Ismanto
Published: October 2023

Penelitian ini memiliki tujuan utama, yakni: (1) Menginvestigasi dampak citra merek terhadap keinginan untuk membeli produk Bank Syariah Indonesia KCP Kolaka. (2) Mengevaluasi pengaruh religiusitas terhadap keinginan untuk membeli produk Bank Syariah Indonesia KCP Kolaka. Metode penelitian yang digunakan dalam studi ini adalah pendekatan kuantitatif eksplanatori yang mencakup pengumpulan data melalui pengamatan, dokumentasi, dan distribusi kuesioner. Seluruh populasi Kabupaten Kolaka menjadi subjek penelitian, dengan sampel sejumlah 130 responden yang dipilih dengan metode purposive sampling berdasarkan kriteria tertentu. Validitas dan reliabilitas instrumen penelitian dijamin menggunakan perangkat lunak SPSS 25.0. Analisis data dilakukan menggunakan Metode Structural Equation Modeling (SEM) berdasarkan Partial Least Square (PLS), dengan pengujian model pengukuran dan model struktural menggunakan Smart PLS 4.0. Hasil penelitian ini menunjukkan adanya pengaruh positif dan signifikan citra merek terhadap keinginan untuk membeli produk, sementara religiusitas juga memiliki dampak yang positif dan signifikan terhadap kecenderungan untuk menggunakan produk tersebut..

Abstract

This study aims to: (1) Examine the effect of brand image on the intention to purchase Bank Syariah Indonesia KCP Kolaka products. (2) Assess the impact of religiosity on the intention to purchase Bank Syariah Indonesia KCP Kolaka products. The research uses an explanatory quantitative approach, including data collection through observation, documentation, and questionnaires. The study covers all residents of Kolaka Regency, with a sample size of 130 respondents selected through purposive sampling. Validity and reliability of research instruments were ensured using SPSS 25.0. Data analysis employed Structural Equation Modeling (SEM) based on Partial Least Square (PLS), with Smart PLS 4.0 used to test the measurement model and the structural model. The findings highlight a positive and significant influence of brand image on product intention, along with a similar positive and significant impact of religiosity on product inclination.
Pengaruh Literasi Keuangan dan Lifestyle Hedon Terhadap Perilaku Keuangan Gen-Z pada Mahasiswa Prodi Manajemen Angkatan 2020 Universitas Indo Global Mandiri Palembang
Authors: Sianipar Bertua Ambarwati , Purnamasari Endah Dewi , Ulum M. Bahrul
Published: October 2023

Perkembangan dunia keuangan saat ini menawarkan banyak pilihan bagi masyarakat dalam mengambil keputusan keuangan. Mengelola keuangan dengan baik merupakan tindakan bijak yang dapat diambil untuk meningkatkan kondisi ekonomi, baik untuk diri sendiri, keluarga maupun organisasi.  Tujuan penelitian ini adalah untuk mengetahui pengaruh literasi keuangan dan lifestyle Hedon terhadap perilaku keuangan Gen-Z pada Mahasiswa Prodi Manajemen Angkatan 2020 Universitas Indo Global Mandiri Palembang. Penelitian ini dilakukan pada mahasiswa prodi manajemen Angkatan tahun 2020 Universitas Indo Global Mandiri Palembang. Jenis penelitian yang digunakan adalah penelitian kuantitatif dengan menyebarkan kuesioner melalui Google form. Sampel penelitian ini terdiri dari 105 mahasiswa. Sumber data penelitian ini adalah data primer dengan menggunakan teknik purposive sampling. Berdasarkan hasil uji t menunjukkan hasil bahwa literasi keuangan dan lifestyle hedon berpengaruh positif dan signifikan terhadap perilaku keuangan Gen-Z pada Mahasiswa Prodi Manajemen Angkatan 2020 Universitas Indo Global Mandiri Palembang.

Abstract

Currently, the financial industry offers several options for individuals to make informed financial decisions. Effective financial management is a wise decision that can improve economic conditions for individuals, their families, and their organizations.  The aim of this study was to evaluate the influence of financial literacy and hedonic lifestyle on the financial behavior of Generation Z students enrolled in the Management Study Program, class of 2020, at Indo Global Mandiri University Palembang. This research comprised students from the Management program, class of 2020, at Indo Global Mandiri University Palembang. The research used a quantitative approach and distributed questionnaires through Google Form. The study gathered data from 105 students. This research obtained primary data using purposive sampling. The t-test results suggest that financial literacy and hedonic lifestyle have a positive and significant effect on Gen-Z financial behavior among students in Indo Global Mandiri University Palembang's Management Study Program.
Keputusan Investasi Cryptocurrency di Purwakarta: Mengungkap Dampak dari Herding dan Overconfidence
Authors: Pranata Rengga Madya
Published: October 2023

Investasi merupakan salah satu cara untuk mengalokasikan dana ke dalam bentuk investasi yang menguntungkan dengan memiliki dimensi waktu jangka panjang. Namun, keputusan investasi yang diambil harus dipertimbangkan dengan baik karena memiliki konsekuensi berjangka panjang pula. penelitian ini untuk menguji pengaruh herding dan overconfidence terhadap keputusan investasi cryptocurrency di PurwakartaPenelitian ini merupakan penelitian kuantitatif dengan melakukan survei terhadap investor cryptocurrency menggunakan kuesioner, sampling penelitian menggunakan aksidental terhadap investor di Purwakarta, responden yang di dapatkan berjumlah 53. Data dianalisis secara statistik untuk memahami pengaruhnya dengan analisis regresi berganda.Hasilnya ditemukan bahwa herding bias memiliki pengaruh positif yang signifikan terhadap keputusan investasi, sementara overconfidence bias juga mempengaruhi keputusan investasi meskipun dengan pengaruh yang lebih rendahInvestor perlu meningkatkan pemahaman tentang cryptocurrency, melakukan analisis yang cermat, dan mengurangi pengaruh perilaku herding dan overconfidence bias untuk membuat keputusan investasi yang lebih rasional.
Pengaruh Elektabilitas Gaya Kepemimpinan dan Lingkungan Kerja Terhadap Tingginya Turnover Karyawan PT. Sumi Rubber Indonesia
Authors: Ridwansyah Ridwansyah , Purwadhi Purwadhi , Andriani Rian
Published: October 2023

The purpose of this research was to find out and analyze the influence of the electability of leadership style and work environment on employee turnover at PT. Sumi Rubber Indonesia together. This research uses a quantitative approach. The samples in this study were employees at PT. Sumi Rubber Indonesia with a total of 73 people. Data collection in this study was in the form of a questionnaire. The data analysis techniques are validity test, reliability test, classical assumption test and multiple linear regression analysis. Hypothesis testing using, t test, f test, R test and R2 test. The results showed that: 1) The electability of leadership style has a significant effect on employee turnover, 2) The work environment has a significant effect on employee turnover, 3) The electability of leadership style and work environment has a significant effect on employee turnover in the Directorate of Sales and Marketing

Keywords: Electability of Leadership Style, Work Environment and Employee Turnover
Pengaruh Brand ambassador dan Keuntungan Reksa Dana Pada Minat Mahasiswa Dalam Berinvestasi Reksa Dana Pada Aplikasi Bibit (Studi Pada STIE Satya Dharma angkatan 2019).
Authors: Putu Devy Isabella Permatawati
Published: October 2023

The purpose of this study was to determine the effect o f brand ambassadors and mutual fund benefits on students' interest in investing in mutual funds in Bibit applications (studies at STIE Satya Dharma class of 2019). The analysis technique used in this research is validity and reliability test, classical assumption test, multiple linear regression analysis, and model feasibility test. The results of the study show that Brand ambassadors have an effect on student interest in investing in mutual funds in the Bibit application (Study at STIE Satya Dharma class of 2019) from the results of hypothesis testing with the T test showing that Brand ambassadors have a positive and significant effect on student interest in investing in mutual funds. Profits affect student interest in investing in mutual funds in the Bibit application (Study at STIE Satya Dharma class of 2019) from the results of hypothesis testing with the T test showing that profits have a positive and significant effect on student interest in investing in mutual funds.
El español en contacto con el francés en Quebec y su estudio gracias al «Corpus oral de la lengua española en Montreal» (COLEM)
Authors: Pato Enrique
Published: October 2023

Este trabajo resume la situación lingüística de Quebec y de su inmigración ‘latina’. Describe, asimismo, la situación del español en la Región metropolitana de Montreal, espacio donde el contacto español-francés se ve favorecido por la continua migración y la percepción local de lo hispano. Por último, gracias a los datos del Corpus oral de la lengua española en Montreal, trata la integración de los migrantes y ejemplifica los principales procesos que tienen lugar en situación de contacto de lenguas y de variedades: préstamos léxicos, uso de ciertos marcadores y un caso concreto de transferencia sintáctica, fenómenos todos ellos fruto del contacto.
Comentario sobre el estudio y la edición crítica de «Las dos bandoleras y fundación de la Santa Hermandad de Toledo», comedia atribuida a Lope de Vega
Authors: Zesiger Marie
Published: October 2023

El artículo siguiente presenta el trabajo de maestría «Estudio y edición crítica de Las dos bandoleras y fundación de la Santa Hermandad de Toledo, comedia atribuida a Lope de Vega», que fue premiado en 2020 por la Sociedad Suiza de Estudios Hispánicos. Este trabajo pretendía rescatar una comedia atribuida a Lope de Vega para cuestionar y tratar de demostrar su presunta autoría. Nuestro método de análisis se basó en la combinación de factores métricos, de ortología y de estilometría, pero también trabajamos sobre el contexto de escritura de la obra y su temática histórica y legendaria
barranqueño
Authors: Abreu Vilaranda Kevin de
Published: October 2023

En este artículo, se tratará de describir el estado actual del barranqueño, una variedad mixta resultante del contacto entre dos lenguas: el portugués y el español. Este dialecto ha sido poco estudiado a lo largo de los años, desde el primer trabajo del lingüista José Leite de Vasconcelos en la primera mitad del siglo XX, hasta los estudios de María Victoria Navas Sánchez-Élez en la década de los 90. La falta de estudios y su relativa lejanía en el tiempo justifican una actualización del estado de esta variedad rayana. En este artículo, se analizarán los componentes lingüísticos actuales del barranqueño y las actitudes lingüísticas de los hablantes acerca de su propio dialecto y de las lenguas con las cuales están en contacto: el portugués y el español.
Guerra Civil en viñetas: los impresos efímeros entre dos siglos Luana Bermúdez
Authors: Bermúdez Luana
Published: October 2023

El presente artículo pretende estudiar las principales estra-tegias propagandísticas de los impresos efímeros que circularon du-rante la Guerra Civil española, al igual que analizar cómo la novela gráfica Picasso en la Guerra Civil (2019), de Daniel Torres, retoma y reelabora dichos impresos. Así, en primer lugar, exploraremos las características de los documentos que reúnen textos e imágenes para vehicular un mensaje político. En un segundo lugar, desgranaremos los niveles de ficción que componen la obra de Torres y analizaremos algunas reelaboraciones de impresos efímeros editados entre 1936 y 1939, tales como los carteles de guerra, las pancartas, las revistas, las caricaturas y las aleluyas. Según veremos, Torres parte de materiales auténticos heterogéneos, los mezcla con varias técnicas propagandísticas usadas durante la contienda española y llega a un discurso metaliterario sobre las posibilidades de los géneros gráficos.
Memoria y exilio
Authors: Zárate Julio
Published: October 2023

El presente artículo plantea una lectura comparada de La diáspora (1989) y Moronga (2018), de Horacio Castellanos Moya. Se postula como eje reflexivo la manera en la que ha evolucionado, a casi treinta años de distancia, la mirada del autor salvadoreño en torno al tratamiento ficcional de lo que él mismo califica como “éxodo caótico” centroamericano, producto de la guerra civil y de la inmanencia de la violencia y la pobreza en esta región. Se estudiará de qué manera la guerra ha dejado un puñado de náufragos que sobreviven en un mundo al que asisten como espectadores, viviendo con el norte puesto en el pasado. Asimismo, se analizará cómo la distancia y el tiempo parecen incapaces, en ambas novelas, de borrar las huellas de la guerra, las cuales se mantienen latentes en la memoria de los personajes, incluso después de haberse exiliado en México y los Estados Unidos. Castellanos Moya construye un puente, a lo largo de su obra, entre la ficción y el contexto histórico salvadoreño. El puente se vuelve, en su obra más reciente, distante y cínico ante la desilusión y la desesperanza de encontrar una solución a la violencia.
«La isla de los hombres solos» de José León Sánchez y la cuestión autobiográfico-testimonial
Authors: Chen Sham Jorge
Published: October 2023

Desde el prólogo autorial y el incipit, la novela La isla de los hombres solos (1967) problematiza la función del testimonio, al plantear la complejidad temporal de la escritura autobiográfica; la novela posibilita su pacto narrativo bajo la autenticidad y la veracidad del discurso y analiza las capacidades de la autoría con los tópicos clásicos de la captatio benevolentiae y la excusatio propter infirmitatem. La solicitud, de que se refiera al caso por parte de un auditor/lector interno a la manera de la picaresca, aclara, pues, la perspectiva del testimonio en el que la amplificación del dolor y los sufrimientos colectivos permiten no sólo justificar sino exculparse. Este trabajo planteará los límites de la cuestión autobiográfico-testimonial en la obra seminal del laureado escritor costarricense.
«Me llaman el desaparecido, que cuando llega ya se ha ido»
Authors: Rosa Silvia
Published: October 2023

En el presente artículo nos centramos en las nuevas dimensiones de la figura del desaparecido en películas documentales y docuficcionales recientes en América Central, particularmente revisamos cineastas de Guatemala, Nicaragua y El Salvador. El objetivo de la investigación es extender la categoría ontológica y estética del “desaparecido original” (Gatti, 2008), que ha sido trabajada en países del Cono Sur (Argentina, Chile, Paraguay), a fines de repensarla en las actuales condiciones sociales, políticas y estéticas de Mesoamérica. La particular situación del istmo presenta problemáticas propias que precisan formas también propias de representación, como, por ejemplo, la “desaparición en tránsito”, la “desaparición voluntaria” o la “desaparición en potencia”. Todos estos conflictos son los que el actual celuloide centroamericano tematiza en sus cintas.
Dossier: Mi tesis en 15 minutos. Nuevos horizontes de investigación. Introducción
Authors: Bizzarri Hugo O. , Ramírez Santacruz Francisco
Published: October 2023

Resumen
Hacia una nueva definición del yanito
Authors: Rodríguez García Marta
Published: October 2023

Gibraltar, como enclave británico situado en el sur de la Península Ibérica, presenta un panorama lingüístico, social y cultural muy rico. Este artículo es parte de una tesis doctoral y presenta una reflexión sobre la variedad de habla local, el yanito, con el objetivo de ofrecer una nueva definición de esta variedad en la generación de jóvenes adultos. Para ello, se presentan ejemplos extraídos de un corpus con un total de 48 participantes (entre 16 y 35 años de edad) formado por 16 grupos de enfoque de 3 personas cada uno. Los y las participantes siguen una guía de conversación para estimular la discusión de temas de interés como, en este caso, la variedad local. Se sostiene que el término yanito ha sufrido una extensión semántica y que, para la generación de jóvenes adultos, este código local se ha visto envuelto en el proceso de transformación de su lengua base, reflejo del cambio lingüístico en la comunidad.
habla del Chocó
Authors: Kobel Diana Cecilia
Published: October 2023

Este artículo expone algunos fenómenos lingüísticos del habla cotidiana del municipio de Medio San Juan, Chocó, Colombia. Se han jerarquizado fenómenos lingüísticos que algunos lingüistas observaron de modo repetitivo en el habla de las diferentes comunidades afrodescendientes en América. Junto con la hipótesis de partida ―la existencia de un habla afrohispánica o una variedad colombiana adscrita a los afrodescendientes―, se han expuesto objetivos tendientes a confirmarla o descartarla. Se indican las principales preguntas de investigación. Posteriormente, se ofrece una reseña metodológica aplicable a trabajos de sociología lingüística. Finalmente, se abordan, de modo general, tres cuestiones básicas en los estudios de las variables afrohispánicas: 1) la matriz africana originaria, referente a indagaciones sobre el origen o lugar de África del cual proviene la población afrodescendiente del Chocó; 2) el signo lingüístico, teniendo en cuenta que el rompimiento de la transmisión hereditaria de la lengua genera un “conflicto” o evolución lingüística, y 3) la pronunciación de la oclusiva glotal en las tierras bajas del Pacífico colombiano. Se ha seleccionado una serie de ejemplos léxicos del habla cotidiana del Chocó. Este trabajo pretende dar un tratamiento introductorio a la temática ex puesta, lejos de postular conclusiones o tesis propiamente dichas.
Representaciones transnacionales en los relatos de viajes
Authors: Barreira de Sousa Catarina
Published: October 2023

En un contexto mundial globalizado se valoran cada vez más los aportes teóricos para comprender las relaciones transnacionales. En ese sentido, nos proponemos poner de relieve el potencial de los textos viáticos, recurriendo a un abordaje imagológico. Ilustraremos algunos presupuestos con tres relatos de viaje contextualmente muy distintos: uno hispánico, con Por tierras de España y Portugal, de Miguel de Unamuno (la gran referencia literaria de la imagología intraibérica); otro francófono, con Viaje al Congo de André Gide (representación del Otro en tiempos coloniales); y, por fin, uno lusófono con Breviário do Brasil, de Agustina Bessa-Luís. En éste se tratará más bien de un viaje a la memoria colonial de Portugal.
Dossier: Teoría y práctica de la narrativa breve hispánica. Introducción
Authors: Bizzarri Hugo O. , Ramírez Santacruz Francisco
Published: October 2023

Resumen
Fragmento y acontecimiento en «Challenger» de Guillem López
Authors: Kunz Marco
Published: October 2023

La novela Challenger (2015) del escritor español Guillem López se compone de 72 capítulos, protagonizados por otros tantos personajes, que narran fragmentos de un solo día en Miami, el 28 de enero de 1986, fecha en que explotó el transbordador espacial Challenger, poco después de su despegue. En este artículo reflexionamos sobre las relaciones entre la fragmentación y el acontecimiento histórico. Analizamos las técnicas utilizadas en Challenger para enlazar los fragmentos en un constructo ficcional coherente que combina motivos de numerosos genres y logra un precario pero suficiente equilibrio entre fuerzas centrípetas y centrífugas. Pretendemos mostrar que, haciendo un uso moderado de procedimientos “experimentales” muy difundidos en la narrativa contemporánea más “vanguardista”, esta novela tiende un puente entre la cultura pop y la literatura elitista.
Between interpretation and application: case-specific CJEU judgments in the preliminary ruling procedure
Authors: Krommendijk Jasper
Published: October 2023

The division of roles between the CJEU and national courts in the preliminary ruling procedure is clearly defined, at least on paper. The CJEU interprets EU law and the referring national court applies this interpretation to the case pending before it. In the literature, there are often complaints that this is different in practice and that the CJEU all too often steps into the domain of the national judge by not limiting itself to only interpreting EU law but also applying the interpretation to the national legal or factual context. Too much case specificity may put the referring court in a difficult position, especially in cassation appeals when the facts have already been established. Little is known as to whether the CJEU adheres to the clear ‘separation of functions’. This contribution analyses to what extent and why the CJEU abides by this division. It examines 55 judgments delivered during the period between 1 January 2020 and 22 March 2021 in response to questions from courts in five EU Member States (the Netherlands, Ireland, the Czech Republic, Sweden and Greece). This structured case law analysis aids the identification of factors that contribute to outcome-oriented judgments. The article also critically examines the approach of the CJEU from a normative perspective weighing the pros and cons.
Pengaruh Ekstra Lidah Buaya ( Aloe vera) Sebagai ZPT Alami untuk Pertumbuhan Tanaman Kacang Tanah (Arachis hypogaea)
Authors: Srg Rianto Joni , Hrp Rahmi Sari
Published: October 2023

Aloe Vera plants (Aloe vera) contain minerals including selenium, calcium, magnesium, potassium and several enzymes of sugar, fatty acids, and also growth hormones, namely auxin and gibberellin. This study was conducted to determine the extra effect of Aloe vera on the growth of peanut plants. The study was conducted by providing treatment in the form of watering peanut plants with Aloe vera solution exta at several different concentrations and controls as a reference. The treatment was carried out for 14 days and observation of the growth of green bean plants was carried out every 3 days. The data obtained were tested using One-Way ANOVA, Then analyzed descriptively. The results showed that peanut plants had significantly different growth in the 10% gel concentration treatment which resulted in the highest plant height, while the number of leaves, leaf area, and stem diameter did not have a significant effect. Keywords: aloe vera, growth, ZPT
Variasi Dialek Pulau Pinang: Analisis Geolinguistik
Authors: Mohamed Sultan Fazal Mohamed , Ismail Anas
Published: October 2023

Geolinguistik menggabungkan geografi dan linguistik, serta menggunakan teknologi Sistem Maklumat Geografi (GIS) untuk memeta dan mencari sempadan dialek sesuatu bahasa dengan tepat varian leksikal dalamnya. Dialek Melayu di negeri Pulau Pinang yang bersempadan dengan negeri Kedah, Perlis dan Perak dikenal pasti menggunakan teknologi GIS. Oleh itu, kajian ini akan mengenal pasti penggunaan dan penyebaran variasi leksikal “kapal”, “kuih” dan “panas”, serta menjana pemetaan isoglos dan kolopret variasi leksikal ini di negeri Pulau Pinang dengan menggunakan Sistem Maklumat Geografi (GIS). Kajian Geolinguistik ini dimulakan dengan pengumpulan data leksikal yang dibuat melalui kajian lapangan di 27 buah kampung di seluruh daerah di negeri Pulau Pinang. Jumlah kampung yang sedikit disebabkan oleh saiz Pulau Pinang yang kecil. Seramai 123 responden daripada generasi tua dan muda telah disoal siasat. Kajian ini telah membuktikan bahawa varian leksikal “kapal”, “kuih” dan “panas” adalah berbeza-beza. Varian ini dapat membantu penemuan dialek baharu, iaitu Pulau Pinang, Kedah, dan Patani Sik, serta menandakan penyebaran ini dengan tepatnya.
IMPACT OF MICROBIAL ART ON ADVANCING STUDENTS' CULTURING PROFICIENCY IN MICROBIOLOGY EDUCATION
Authors: Sulaiman Suraya , Wan Ismail Wan Nordini Hasnor , Othman Mohd Izani , Mohd Najib Mohd Nadzri
Published: October 2023

Abstract: Microbial art, an emerging trend in microbiology education, integrates artistic activities to enhance critical thinking and deepen comprehension of intricate scientific concepts. This study examines the effect of microbial art activity on students' understanding and competency of microbiological culturing methods. A qualitative content analysis was employed to evaluate the comprehension of 108 students who participated in the microbial activity, which encompassed the assessment of both their visual creations and written reports. The relationship between students' understanding of bacterial culturing techniques and the quality of their artworks was assessed using descriptive statistics and Pearson's correlation coefficient. The quality of the artwork was classified as poor, moderate, and good, reflecting students' cultivation skills, with 53% at a moderate level, 30% good, and only 17% having poor artwork quality. According to the analysis of the students' written reports, it was found that 71% of the students exhibited a strong understanding of the activity, while 29% showed an average level of understanding. However, there was no correlation found between students' understanding and the quality of their artwork. This study demonstrates that incorporating microbial art into science education can improve student cultivation techniques by providing an engaging and creative way to practice microbiology skills.

Keywords: Artworks; Culturing technique; Enhance; Microbial art; Microbiology education
Conceptual Design And Simulation Analysis Of Dough Mixer-Maker Machine
Authors: Abdul Fatah Ireana Yusra , Nor Aini Ramli  , Razwan Rohimi
Published: October 2023

Collecting information on the use of kitchen appliances i.e. dough mixers is important to provide a more efficient and high-quality system and design. Nowadays, dough mixers that can only knead the dough are widely used to get a complete dough while saving time. Therefore, a dough mixer machine that operates with two functions such as McDuo Maker Machine is developed to save users time in kneading the dough as well as forming the finished dough into a cake according to the set mold. Currently, the machines developed in the market only work for kneading dough. Therefore, this machine is developed to produce a machine that can operate with two functions namely mixing the dough and forming the dough into a cake.
Preliminary Ethnoichthyological Assessment: Fish Consumption Patterns among Orang Asli Semelai (Aborigines: Proto-Malay) in Tasek Bera, Pahang
Authors: Abdullah-Fauzi Nurfatiha Akmal Fawwazah , Othman Nursyuhada , Haris Hidayah , Ramli Farah Farhana , Sariyati Nur Hartini , Najmuddin Mohd Faudzir , Ilham-Norhakim Mohd Lokman , Abdul-Latiff Muhammad Abu Bakar
Published: October 2023

Ethnoichthyology, as a field of study, examines the indigenous knowledge held by ethnic groups concerning different fish species. Despite its significance in understanding traditional fishing practices and cultural connections to aquatic resources, data on fish species consumption among the Orang Asli Semelai community remain limited. Therefore, this ethnoichthyological preliminary study aims to address this research gap by documenting the fish species utilized by the Orang Asli Semelai in the Tasek Bera region of Pahang, Malaysia. To achieve this objective, a comprehensive survey and interview session were conducted with a small sample size of four randomly chosen respondents. The study identified 15 fish species solely consumed as food by the community. The most commonly consumed fish species were the Climbing Perch (Anabas testudineus) and Snakehead Murrel (Channa striata). Additionally, the study revealed the presence of the Critically Endangered Jullien's Golden Carp (Probarbus jullieni) among the consumed species, indicating the urgent need for conservation efforts. The findings underscore the significance of integrating sustainable fishing practices and conservation efforts to protect the unique ecosystem of Tasek Bera and preserve the cultural heritage of the Orang Asli Semelai community. Further comprehensive studies and collaborative approaches are vital to safeguarding the region's aquatic biodiversity and ensuring the community's food security sustainably.
Diurnal Variation of Blood Pressure and Arterial Stiffness in Chronic Kidney Disease
Authors: Arief Akbar Kgs M Yusuf , Novadian Suhaimi  , Zulkhair Ali  , Suprapti Slamet  , Ian Effendi  , Syahpri Putra Wangsa  , Deddy Primadona Mulia
Published: October 2023

Hypertension and chronic kidney disease (CKD) are interrelated public health problems throughout the world. Hypertension accompanied by CKD is mostly difficult to control. Difficulty in controlling blood pressure (BP) is known from changes in the diurnal variation of BP over 24 hours in CKD patients with a pattern of non-dipping and reverse dipping at night and an increase in pulse pressure due to arterial stiffness that occurs in CKD, resulting in a high incidence of nocturnal hypertension and masked hypertension. Nocturnal hypertension in CKD has a significant prognostic risk of increased risk of cardiovascular disease and cause of death. Therefore, guidelines for the management of hypertension strongly recommend that patients with hypertension have blood pressure well controlled at all times, especially to improve hypertension control at night in CKD patients.
Examining/Understanding the Reading Culture and Comprehension Abilities of Learners of English as a Foreign Language in Uganda
Authors: Rugyema Rodney
Published: October 2023

In this study, I analysed the reading culture and its influence on reading comprehension of learners of English as a Foreign Language (EFL) in Uganda. The data were collected by interviewing ten EFL teachers in order to gather their views of their learners’ reading culture and comprehension abilities. Data were analysed using Vroom’s Expectancy theory. Findings indicate that the EFL learners were enthusiastic about reading even beyond the classroom reading tasks. 30% of the teachers interviewed confirmed that the learners had a positive attitude towards reading as part of their language learning, hence a confirmation of their good reading culture. The rest of the teachers interviewed confirmed that 70% of the learners possess a poor reading culture. The study further confirmed the presence of a strong link between the learners’ reading culture and reading comprehension achievement. The majority of the teachers agreed that the positive reading culture exhibited by their EFL learners significantly contributed to their reading comprehension. The learners with a poor reading culture also exhibited poor reading comprehension abilities because they lacked frequent reading comprehension opportunities. The study concludes that the majority of EFL learners lack a good reading culture. There was a clear relationship between the reading culture and the learners’ attainment of reading comprehension. This is confirmed by the fact that in cases where the reading culture was positive, the learners’ reading comprehension abilities were better
ANALISIS ERGONOMIS PADA ALAT MINI CULTIVATOR PENGOLAH LAHAN PERTANIAN BERDASARKAN METODE NBM DAN OWAS
Authors: Mahmuda Muhammad , Sukardi  , Wiyogo
Published: October 2023

This research aims to: (1) Analyzing the ergonomics of mini cultivator tools based on the Nordic Body Map (NBM) method, and (2) Analyzing the ergonomics of mini cultivator tools based on the Ovako Working Posture Analysis System (OWAS) method. The method in this study was experimental, and the data were analyzed by quantitative descriptive method. The research sample amounted to 5 farmers. The results showed that in the initial posture, namely the upright back position, a score of 1122 category 1 was obtained, which means that the posture is not dangerous and does not need to be improved. In the work posture when running the mini cultivator tool, a score of 2173 category 3 is obtained, which means that the straight work posture must be improved immediately. The results of filling out the NBM questionnaire show that farmers still feel "a little sick" in straight work postures. Meanwhile, the turning posture obtained a score of 4173 category 3 which means that immediate improvement is needed. The results of filling out the NBM questionnaire show that farmers still feel "very sick" in the turning posture. Thus, the mini cultivator tool still needs improvement in several aspects of ergonomics and is discussed in the results of this study
Overcoming phenotypic switching: targeting protein-protein interactions in cancer
Authors: Ladias Christos , Papakotoulas Pavlos , Papaioannou Maria , Papanikolaou Nikolaos A.
Published: October 2023

Alternative protein-protein interactions (PPIs) arising from mutations or post-translational modifications (PTMs), termed phenotypic switching (PS), are critical for the transmission of alternative pathogenic signals and are particularly significant in cancer. In recent years, PPIs have emerged as promising targets for rational drug design, primarily because their high specificity facilitates targeting of disease-related signaling pathways. However, obstacles exist at the molecular level that arise from the properties of the interaction interfaces and the propensity of small molecule drugs to interact with more than one cleft surface. The difficulty in identifying small molecules that act as activators or inhibitors to counteract the biological effects of mutations raises issues that have not been encountered before. For example, small molecules can bind tightly but may not act as drugs or bind to multiple sites (interaction promiscuity). Another reason is the absence of significant clefts on protein surfaces; if a pocket is present, it may be too small, or its geometry may prevent binding. PS, which arises from oncogenic (alternative) signaling, causes drug resistance and forms the basis for the systemic robustness of tumors. In this review, the properties of PPI interfaces relevant to the design and development of targeting drugs are examined. In addition, the interactions between three tyrosine kinase inhibitors (TKIs) employed as drugs are discussed. Finally, potential novel targets of one of these drugs were identified in silico.
Impact of coronavirus disease 2019 pandemic on good clinical practice trials in oncology
Authors: Agostinelli Veronica , Ballatore Zelmira , Ricci Giulia , Lucarelli Alessandra , Burattini Michela , Mariotti Lorenzo , Catani Claudia , Tarantino Valentina , Berardi Rossana
Published: October 2023

Aim: Coronavirus disease 2019 (COVID-19) became pandemic on 11th March 2020 and it deeply stressed the healthcare system. Cancer patients represent a vulnerable population, so many recommendations have been approved to ensure optimal management. Clinical research was notably impacted by COVID too. This review aims to analyze the challenges occurred during a pandemic for the management of enrolled patients (enrollment, use of telemedicine visits, study procedures) and for the clinical trials system (from feasibility to selection visit, site initiation visit, monitorings, use of e-signature, deviations and discontinuations).
Methods: The studies included in the present review were selected from PubMed/Google Scholar/ScienceDirect databases.
Results: During the first phase of pandemic many clinical trials were suspended in accrual and, as the pandemic progressed, recommendations were established to guarantee the safety and the continuity of care of enrolled patients. In addition, lot of new strategies was found during the pandemic to reduce the negative consequences on clinical trial performance and to guarantee new opportunities of care in the respect of good clinical practice (GCP) in a bad scenario.
Conclusions: Among all modifiers, investigators would prefer to maintain the positive ones such as pragmatic and simplified trial designs and protocols, reducing in-person visits when not necessary and to minimizing sponsor and contract research organizations (CROs) visits.