bluuebunny/crossref_metadata_2025 huggingface dataset:
Detection of Mycoplasma bovigenitalium and Mycoplasma tauri in Holstein Friesian dairy cows with subclinical endometritis
Authors: Milovanović Bojan , Kureljušić Branislav , Milićević Vesna , Zdravković Nemanja , Kureljušić Jasna , Marinković Darko , Maletić Milan
Published: September 2023

Mycoplasma spp. is the cause of serious cattle health disorders that lead to poor reproductive efficiency. Chronic seminal vesiculitis, infertility, vulvovaginitis and dystocia were observed in Mycoplasma spp. infection. The objectives of the present study were to investigate the frequency o f Mycoplasmas in the uterus of postpartum dairy cows and its potential role in the occurrence of subclinical endometritis. Our study included 102 Holstein Friesian dairy cows 22-32 days postpartum. Uterine samples for cytological, bacteriological, and molecular analysis were provided using Cytoprint A I®. Metricheck® was used for the assessment of cervicovaginal mucus. After detection of Mycoplasma spp. genome in uterine samples, the swabs of the vulva, vagina, nasal swab, and samples of milk were sampled in order to exclude possible contamination with other microorganisms as potential trigger of subclinical endometritis. The genome of Mycoplasma spp. in the uterus was confirmed in 4 cows (2.40%). Sequencing of the 16S RNA revealed that detected mycoplasmas belonged to Mycoplasma bovigenitalium and Mycoplasma tauri species, with a prevalence of 1.80% and 0.6%, respectively. The cytological evaluation showed a 69.90%, 54.87% and 48.33% of polymorphonuclear cells for M. bovigenitalium positive cows, and 61.64% for M. tauri positive cow. Bacteriological examination revealed Trueperella pyogenes in uterine samples in all 4 observed cows. This is the first study where M. tauri was detected in the uterus of a live cow with subclinical enodmetritis. In this paper we hypothesized that M. bovigenitalium and M. tauri may have a certain role in the etiology of subclinical enodmetritis.
A Real-World Benchmark Problem for Global Optimization
Authors: Yuriy Romasevych , Viatcheslav Loveikin , Borys Bakay
Published: September 2023

The paper presents the statement of the problem of dynamical system „crane-load” optimal control. The acceleration period is under consideration and control must meet the minimum duration condition as well as load oscillations elimination. The objective function, which ensures the final condition satisfaction, is developed and analyzed in terms of its topology features. It includes three arguments and their searching is the essence of the benchmark problem. Two variants of the problem are proposed with varied objective function parameters. Twelve agent-based optimization algorithms have been applied to find solutions to a bunch of problems. A brief analysis of the performance of the algorithms reveals their weaknesses and advantages. Thus, the proposed real-world problem may be exploited to estimate the optimization algorithms’ search performance.
Analysis of Energy and Network Cost Effectiveness of Scheduling Strategies in Datacentre
Authors: Bhutto Afia , Chandio Aftab Ahmed , Luhano Kirshan Kumar , Korejo Imtiaz Ali
Published: September 2023

In parallel and distributed computing, cloud computing is progressively replacing the traditional computing paradigm. The cloud is made up of a set of virtualized resources in a data center that can be configured according to users’ needs. In other words, cloud computing faces the problem of a huge number of users requesting unlimited jobs for execution on a limited number of resources, which increases energy consumption and the network cost of the system. This study provides a complete analysis of classic scheduling techniques specifically for handling data-intensive workloads to see the effectiveness of the energy and network costs of the system. The workload is selected from a real-world data center. Moreover, this study offers the pros and cons of several classical heuristics-based job scheduling techniques that take into account the time and cost of transferring data from multiple sources. This study is useful for selecting appropriate scheduling techniques for appropriate environments.
A Novel Hypergraph Clustered Gray Relational Analysis HGPSO Algorithm for Data Aggregation in WSN
Authors: Pushkin Shailendra , Ranvijay
Published: September 2023

Wireless Sensor Networks (WSN) aggregate data from multiple sensors and transfer it to a central node. Sensor nodes should use as little energy as possible to aggregate data. This work has focused on optimal clustering and cluster head node selection to save energy. HyperGraphs (HGC) and cluster head selection based on distance and energy consumption are unique approaches to spectral clustering. GRA computes a relational matrix to select the cluster head. The network’s Moving Agent (MA) may use Hypergraphed Particle Swarm Optimization (HGPSO) to collect data from cluster heads. Compared to the clustering algorithm without agent movement, the HGC-GRA-HGPSO approach has increased residual energy by 5.59% and packets by 2.44%. It also has improved residual energy by 2.45% compared to Grey Wolf Optimizer-based Clustering (GWO-C).
An innovative conceptual model for education and training on hybrid warfare
Authors: Tudorache Paul , Bârsan Ghiță , Jobbágy Zoltán , Cîrdei Alin , Gligorea Ilie
Published: September 2023

This study aims to present an innovative conceptual model of learning, teaching, and training that appears to be applicable to the field of hybrid warfare. It is based on integrating three critical elements such as reference curriculum, teaching methodology, and online support capabilities. By using qualitative research through correlating critical analysis of relevant sources, logical scheme, and cognitive task analysis, each descriptive element is analysed in order to provide an eloquent image of the proposed conceptual model. Also, to gain real feedback on the proposed model as well as on its constitutive elements, the quantitative research using statistical data grouping is performed. The analysis and interpretation of the collected data demonstrate not only a high interest in the designed conceptual model, but also a positive impact at the level of each descriptive element on the academic staff and students from the military and civilian university environment.
Poverty Reduction: Analysis of Factors Affecting Poverty in Lithuania
Authors: Aleksandravičienė Akvilė , Barišauskaitė Gintarė , Ruzveltaitė Lina
Published: September 2023

The purpose of this paper is to evaluate poverty reduction possibilities determining the effect of average wage and unemployment on poverty, identifying the factor that is a more important predictor of poverty in Lithuania. Based on scientific literature analysis, we identify the factors that determine the phenomenon under study. We perform a statistical analysis of the collected data in the period of 2008–2021 to identify trends and patterns in the factors under consideration. The ordinary least squares method allows to estimate the impact of the selected factors on poverty. The results show that unemployment has a statistically significant positive effect (based on the sign of the estimated parameter of the regression model) on poverty, while average wage has a statistically significant negative effect on poverty. Based on the obtained results, we present possible solutions to company managers on how they could contribute to reducing poverty in the country. We conclude that company managers could apply more sustainable development goals in their businesses, reduce gender inequality, increase wages, hire unskilled workers, and help them to improve. In this way, company managers could contribute to reducing poverty in the country.
Analysis of Injuries and Cause of Death in Fatal Accidents with Farm Tractors
Authors: Slovic Zivana , Vitosevic Katarina , Todorovic Danijela , Todorovic Milos
Published: September 2023

Farm tractor accidents are a frequent cause of death for people in agricultural field of work. The aim of this study was to evaluate the characteristics of the fatal farm tractor accidents, as well as the most significant types of injuries and causes of death. Research is based on epidemiological criteria of subjects, traffic participation, cause of death, distribution of injury, outliving period and toxicological details. The study included 22 (4.2%) farm tractor related fatalities out of all 525 subjects who died from sustained injuries or complications of the injuries sustained in road traffic accidents. The highest number of deaths was reported in men in 95.5%. The highest percentage died of bleeding out (41%), while in 18% of cases, complications that occurred during the outliving period were the cause of death. Analyzing injuries through organ systems, it is observed that the highest number of farm tractor drivers had a chest injury (90%), and the most common chest injury was a rib fracture (82%). When determining the outliving period, the highest number of fatal farm tractor drivers died at the scene of accidents (68.2%). Of all of the subjects, 32% were under the influence of alcohol, while 23% had blood alcohol concentration level greater than 0.5 ‰. The high mortality of farm tractor drivers can be reduced by introducing a mandatory rollover protective structures system and the use of a seat belt in farm tractors with cabs, which would reduce the possibility of the driver falling out of the farm tractor seat and additional injuries due to rollover.
Types and functions of precedent names in English-language cinematic discourse
Authors: Bushueva L. , Muliukina A.
Published: September 2023

The subject of this study is precedent names in the English-language cinematic discourse. The focus is placed on determining the functional potential of precedent names in this type of discourse. In this work, precedent names are considered as a kind of precedent phenomena: names of personalities, events and works of fiction. The study of precedent names has significance within the framework of cultural linguistics, cognitive science and intertextuality theory, as precedent names contain information about important cultural and historical phenomena, give insights into the mechanism of metaphorization, and serve to create intertextual connections. The frequency of their use in different types of discourse, especially in cinematic discourse, is steadily increasing, which explains the relevance of research in this field. Using the methods of discourse analysis, functional-semantic analysis, inductive analysis and continuous sampling, we examine the types of precedent names, source spheres and the functions that these lexical units perform in cinematic discourse. Such analysis makes it possible to establish the cultural significance of personalities, events, and other phenomena, as well as their reflection in such a mass art form as cinematography. Due to its mass appeal and depiction of various social groups, cinematic discourse is of particular interest within the framework of sociolinguistics in regard to such culturally significant units as precedent names. The analysis of the functions of precedent names allows one to establish their role in cinematic discourse, their artistic value, semantic potential and cultural significance. The analysis revealed which types of precedent names are most frequently used in the English-language cinematic discourse (anthroponyms and names of works of art); identified productive sources of precedent names (the sphere of art and the social sphere); and introduced a list of characteristic functions that precedent names perform in cinematic discourse (among which ludic and evaluative functions are especially prominent).
Artificial Intelligence in Medicine: Progress, Challenges, and Promises
Authors: Choi Yuen Yung Audrey
Published: September 2023

This article discusses the potential of artificial intelligence (AI) in medicine to address complex challenges, from personalized treatment to difficult diagnoses. The use of AI in medicine has exhibited remarkable performance in various fields, including evidence-based clinical decision support, AI-assisted surgery, and electronic health records analysis. However, challenges remain, such as data silos and potential biases in AI training data. Despite these challenges, AI technology has the potential to transform healthcare in significant ways, and ongoing research and development, collaborations among stakeholders, and innovative initiatives can help ensure its safe and ethical use in medicine and healthcare.
Bootstrap Fourier AARDL Yöntemiyle J Eğrisi Hipotezinin Türkiye’nin Balkanlarla Dış Ticaretinde Geçerliliğinin Analizi
Authors: ÖZÇELİK Oğuzhan
Published: September 2023

Bu araştırmada Türkiye’nin 7 Balkan Ülkesiyle olan ikili ticaretinde J Eğrisi Hipotezinin geçerliliği, 2000-2022 dönemi aylık verileri kullanılarak, Fourier zaman serisi analizi yöntemiyle incelenmiştir. Serilerin durağanlık seviyeleri Enders ve Lee (2012) Fourier ADF birim kök testiyle araştırılmış, eşbütünleşme sınaması ve regresyon analizlerinde McNown vd. (2018), Sam vd. (2019) ve Solarin (2019) çalışmalarıyla geliştirilen Fourier Bootstrap AARDL yöntemiyle yapılmıştır. Eşbütünleşme testlerinde; Macaristan, Makedonya, Sırbistan ve Bosna-Hersek’te eşbütünleşme olmadığı görülürken, Bulgaristan, Hırvatistan ve Karadağ’da eşbütünleşme tespit edilmiştir. Son üç ülke için gerçekleştirilen analizlerde; reel döviz kurundaki artışların Türkiye’nin Bulgaristan, Hırvatistan ve Karadağ karşısındaki dış ticaret dengesini kısa dönemde daha da bozduğu, uzun dönemdeyse Bulgaristan ve Karadağ karşısındaki dış ticaret dengesini iyileştirdiği saptanmıştır. Bu nedenle J Eğrisi Hipotezinin Türkiye – Bulgaristan ve Türkiye – Karadağ dış ticaretlerinde geçerli olduğuna karar verilmiştir.
CCL2 Promotes Novel Coronavirus–Mediated Inflammatory Responses in Macrophages
Authors: Ding Fang , Dai Muwei , Kang Xichun , Zhang Xin , Li Li , Zhao Lei , Jiang Ping , Gao Huixia , Yan Huimin
Published: September 2023

Purpose: The hyperinflammatory response is one of the main complications associated with novel coronavirus disease 2019 (COVID-19), and there is no effective treatment for cytokine storm. Therefore, it is important to investigate the key genes associated with severity of the disease.Methods: In this study, we used a microarray data set to analyze the key genes associated with severe illness in patients with COVID-19. The proportion of immune cells was determined using the CIBERSORT algorithm. The key genes were further verified by detecting the levels of cytokines and chemokines in the serum of patients. Additionally, macrophages were stimulated with SARS-CoV-2 spike protein and chemokine ligand (CCL) 2. The expression of cytokines, ERK1/2, and NF-κB in macrophages was detected.Results: Four hub genes were identified. Among them, C-C motif chemokine receptor 2 (CCR2) was an upregulated hub gene, while killer cell lectin-like receptor subfamily K member 1 (KLRK1), macrophage colony-stimulating factor receptor (CSF1R), and CD3D human recombinant protein (CD3D) were downregulated genes. Immune cell type identification found that the proportion of monocytes was higher in patients with severe COVID-19 than that in controls. Moreover, levels of CCL2 were significantly higher in patients with COVID-19. When stimulated with SARS-CoV-2 S protein and CCL2, macrophages secreted more inflammatory cytokines. The expression level of ERK1/2 was elevated.Conclusions: These results suggested that S protein and CCL2 may mediate macrophage inflammatory responses through the ERK1/2 signaling pathway. This study provides a basis for clinical treatment and improves the prognosis of critically ill patients with COVID-19.
Capitalismo epistémico: hacia una crítica de los modos de evaluación
Authors: Farrán Roque
Published: September 2023

Este texto desea ampliar nuestra forma de entender el funcionamiento del capitalismo actual y sus modos de subjetivación, a partir de problematizar nuestras prácticas concretas. Parte de considerar un artículo de David Pavón Cuéllar publicado en esta misma revista, con el cual se coincide en la perspectiva marxista y lacaniana que presenta, para indicar algunos puntos no desarrollados por él; ejemplarmente, el modo de entender el proceso de conocimiento y la evaluación. Para ello me remito a propuestas anteriores que vengo presentando hace tiempo, adelantando aquí un avance conceptual sobre el “fetichismo de la evaluación”.

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This text seeks to broaden the understanding of current capitalism functioning and its modes of subjectivation, beggining with the problematization of our concrete practices. It starts from considering an article by David Pavón Cuéllar published in this same journal, with which I agree on the Marxist and Lacanian perspective presented to indicate some points not developed by him. Specially, the understanding of the process of knowledge and evaluation. Referring to previous elaborations that I have been presenting for some time, anticipating here a conceptual advance on the "fetishism of evaluation".
Ásperos y fragosos caminos de montaña: Dominio y administración en los antiguos caseríos de Caramanta y Chamí durante los siglos XVI-XVIII.
Authors: Gaviria Vargas Laura
Published: September 2023

Este artículo aborda algunos aspectos de la administración española en el suroccidente de loque hoy es Colombia. Por medio de cartas, expedientes, ordenanzas y medidas tomadas porla Corona española, aquí se entiende cómo el dominio territorial tuvo efectos que sólo sepueden observar desde una perspectiva local. En los caseríos coloniales, el control sobre laspoblaciones indígenas del alto Chocó y de las montañas de la antigua Caramanta, operógracias a una constante negociación e interpretación de la institucionalidad, de modo quenunca se dio del todo de manera legal o ilegal. En este texto se ven las exploraciones, losfracasos, las constantes contradicciones administrativas, conflictos y fragmentaciones,además de las estrategias de sometimiento y explotación de dos territorios indígenasdiferentes, ambos ubicados en la cordillera Occidental de los Andes. La propuesta seenmarca en una revisión de la interpretación de la frontera vacía, y analiza de formapertinente el trasfondo de un territorio considerado periférico y salvaje en el periodocolonial.
PERENCANAAN SUMUR RESAPAN UNTUK PENGENDALIAN BANJIR DI WILAYAH KECAMATAN PASAR REBO, JAKARTA TIMUR
Authors: Artiani Gita Puspa , Rodji Achmad Pahrul , Sihombing Sahat Martua , Arga Yonas Prima , Pribadi Gali
Published: September 2023

Kecamatan Pasar Rebo merupakan salah satu kecamatan di Kota Administrasi Jakarta Timur yang terletak antara 106049’35” Bujur Timur dan 06010’37” Lintang Selatan, Luas wilayah kecamatan ini seluas 12,98 km2 (6,88 persen dari luas wilayah Kota Jakarta Timur) yang terbagi dalam 5 (lima) kelurahan meliputi: Kelurahan Baru, Kelurahan Cijantung, Kelurahan Gedong, Kelurahan Kalisari, dan Kelurahan Pekayon. Kecamatan Pasar Rebo termasuk kedalam kawasan rawan pergesaran tanah berdasarkan data Badan Penanggulangan Bencana Daerah (BPBD) DKI Jakarta. Pada tanggal 10 Oktober 2020, banjir akibat hujan deras berada di jalan Lewa  RT 14 RW 08 Kelurahan Pekayon setinggi 50 sentimeter, jalan Swadaya dan jalan Karya Bakti RT 10 RW 11 Kelurahan Cijantung setinggi 1,2 meter, dan jalan Cakrabuawana dan Manunggal Kelurahan Kalisari 1 meter. Permasalahan ini tidak terlepas terhadap belum terintegrasi sistem drainase dengan baik, perilaku masyarakat membuang sampah, pendangkalan saluran, kepadatan bangunan menyebabkan tidak terdapat resapan air, dataran rendah. Sumur resapan adalah salah satu konsep sederhana yang efektif untuk mengurangi aliran permukaan yang dapat menyebabkan banjir dan merupakan kegiatan konservasi sipil teknis sederhana berupa sumuran yang berfungsi untuk menampung, menahan dan meresapkan air permukaan (run-off) ke dalam tanah (akuifer) untuk meningkatkan jumlah dan posisi muka air tanah. Adapun hasil dari pengabdian kepada masyarakat ini berupa kegiatan FGD yang kemudian menjadi bahan pertimbangan untuk finalisasi pembuatan rekomendasi konsep dalam pembuatan desain saluran drainase selanjutnya untuk mendorong pihak-pihak terkait sesuai bidangnya (OPD Pemda), untuk mewujudkan sumur resapan sebagai usulan program kegiatan.
SOSIALISASI MANAJEMEN MASJID GUNA MENDUKUNG MASJID SEBAGAI TEMPAT IBADAH DAN PUSAT PEMBERDAYAAN EKONOMI UMAT PADA PERUMAHAN TANJAKAN INDAH TANGERANG
Authors: Winanti Winanti , Basuki Sucipto , Fayzhall Miyv , Prihastomo Yoga , Suseno Bayu , Sasono Ipang , Budiadyana Nyoman , Nurasiah Nurasiah , Supriyanto Supriyanto , Yusuf Yusuf , Wahyuni Cahya Ayu , Riyani Riyani
Published: September 2023

Masjid Tanjakan Indah saat ini dimanfaatkan semata-mata hanya sebagai tempat ibadah bagi umat Islam. Selain tempat beribadah, masjid difungsikan untuk pengajian TPA dan penerima serta penyalur zakat dan sodaqoh. Masjid belum dimanfaatkan untuk hal lain selain dari kedua hal tersebut.  Masjid terlihat sepi di saat jam-jam tertentu dan akan ramai kembali di waktu orang-orang muslim mengerjakan ibadah sholat. Banyak aktivitas yang dapat dilakukan di lingkungan masjid, pertemuan-pertemuan warga, diskusi, dan kegiatan ekonomi lainnya dapat dilakukan dan dikelola oleh para pengurus masjid. Memaksimalkan fungsi masjid sebagai tempat ibadah dan pusat ekonomi umat bukan hal yang mudah. Dibutuhkan sosialisasi dan pemahaman kepada seluruh warga dan pengurus masjid sebagai penanggung jawab. Sosialisasi dilakukan sebagai salah satu kegiatan pengabdian kepada masyarakat dosen dan mahasiswa Universitas Insan Pembangunan. Narasumber menyampaikan berbagai pengetahuan mengenai fungsi masjid sebagai tempat ibadah dan pusat ekonomi umat yang diikuti oleh masyarakat perumahan Tanjakan Indah. Sosialisasi melibatkan masyarakat di perumahan Tanjakan Indah kabupaten Tangerang, baik laki-laki maupun perempuan. Narasumber menyampaikan materi mengenai bagaimana mengelola keuangan masjid, lingkungan dan membentuk unit-unit sosial dan bisnis melalui kepengurusan DKM masjid. Memanfaatkan berbagai kegiatan ekonomi masyarakat di lingkungan masjid guna meningkatkan ekonomi umat melalui beberapa kegiatan dan membentuk koperasi masjid untuk memfasilitasi berbagai kebutuhan anak-anak yang belajar di TPA dan ibu-ibu majelis taklim. Sosialisasi ini diharapkan dapat menumbuh kembangkan peran masjid sebagai tempat ibadah sekaligus sebagai pusat ekonomi umat di perumahan Tanjakan Indah.
PEMBERDAYAAN PEREMPUAN MELALUI PENYULUHAN LITERASI DIGITAL KEUANGAN
Authors: Susanti Yuyun , Dedeh Dedeh , Ilah Ilah , Yanti Rini Agustin Eka , Mulyadi Endang
Published: September 2023

Perempuan mempunyai peranan yang penting termasuk dalam membuat perencanaan keuangan. Karena pentingnya peranan tersebut, maka perlu memberdayakan perempuan dalam mengatur keuangan, maka diperlukan edukasi tentang literasi keuangan yang memadai. Tujuan dari kegiatan ini adalah peningkatan literasi digital keuangan pada perempuan Dharma Wanita Persatuan SMA/SMK/SLB Banjar. Kegiatan pengabdian ini dilaksanakan melalui metode penyuluhan tentang pentingnya literasi digital keuangan dengan memberikan pengetahuan dan informasi tentang perkembangan digital keuangan, memudahkan untuk mengakses produk dan layanan sektor jasa keuangan secara cepat dan mudah.
Adolescentes em instituição de acolhimento: redes de apoio social e institucional
Authors: Vargas Tainara Giovana Chaves de , Silveira Andressa da , Favero Natalia Barrinuevo , Soccol Keity Laís Siepmann , Costa Marta Cocco da , Cabral Fernanda Beheregaray , Santos Lairany Monteiro dos , Oliveira Juliana Portela de , Soster Francieli Franco
Published: September 2023

Objetivo: Identificar a rede de apoio social e institucional de adolescentes que residem em instituição de acolhimento. Método: Estudo qualitativo, descritivo e participativo, realizado com 12 adolescentes entre 10 e 16 anos de idade. A produção de dados ocorreu nos meses de agosto e setembro de 2021, utilizando o Método Criativo e Sensível com a Dinâmica de Criatividade e Sensibilidade Mapa Falante. As enunciações foram submetidas à Análise de Discurso na corrente francesa. Resultados: A rede de apoio social dos adolescentes é constituída pelos familiares, amigos, alguns profissionais da instituição e as redes sociais, enquanto a rede de apoio institucional é formada pela casa de acolhimento, a escola, os serviços de saúde e os projetos desenvolvidos pela instituição. Conclusão: A rede de apoio de adolescentes institucionalizados oferece suporte emocional, material, instrumental e informacional, sendo valorizadas as relações interpessoais às institucionais, o que evidencia a necessidade de que os profissionais que atuam nesse cenário sejam capacitados para atender além das demandas físicas, também às emocionais.
Let Artificial Intelligence Be Your Shelf Watchdog: The Impact of Intelligent Image Processing-Powered Shelf Monitoring on Product Sales
Authors: Deng Yipu , Zheng Jinyang , Huang Liqiang , Kannan Karthik
Published: September 2023

We collaborated with a leading fast-moving consumer goods (FMCG) manufacturer to investigate how intelligent image processing (IIP)-based shelf monitoring aids manufacturers’ shelf management by using data from a quasi-experiment and a field experiment. We discovered that such artificial intelligence (AI) assistance significantly and consistently improves product sales. Several underlying mechanisms were revealed by our quantitative and qualitative analysis. First, retailers are more likely to comply due to the greater monitoring effectiveness enabled by AI assistance. Second, the positive effect of IIP-based shelf monitoring partially persists after it is terminated, implying that human learning takes place. Third, the value of IIP-based shelf monitoring can be attributed to independent retailers rather than chain retailers. Since the degree of contract heterogeneity is the major difference between these retailers in terms of monitoring, this finding further suggests that AI is relatively more scalable when coping with more heterogeneous instances. Apart from these great benefits, we demonstrate the low marginal costs of implementing IIP-powered shelf monitoring, which indicates its long-term applicability and potential to generate incremental value. Our research contributes to several literature streams and provides managerial insights for practitioners who consider AI-assisted operational models.
МОДЕЛИРОВАНИЕ ПРОЦЕССА РАСПРОСТРАНЕНИЯ ЭЛЕКТРОМАГНИТНЫХ ВОЛН В РАДИОПОГЛОЩАЮЩИХ Ni–Zn ФЕРРИТАХ
Authors: Игошина С.Е. , Мухаев Д.А. , Крупкин Е.И. , Карманов А.А.
Published: September 2023

Никель-цинковые (Ni–Zn) и магний-цинковые ферриты (Mg–Zn), а также композиты на их основе, являются одним из наиболее перспективных радиопоглощающих материалов, которые могут эффективно поглощать электромагнитное излучение в диапазоне частот от нескольких МГц до единиц ГГц. Многие вопросы, связанные с радиопоглощающими свойствами данных материалов, остаются открытыми до сих пор, что является следствием влиянием параметров образца, как на частотные зависимости магнитной и диэлектрической проницаемости, так и на параметры доменных стенок. В рамках настоящей работы предложена математическая модель процесса распространения электромагнитных волн в радиопоглощающих Ni–Zn ферритах. Поставлены граничные и начальные условия, учитывающие геометрию и микроструктуру образцов. Решение сформулированной краевой задачи на отрезке с использованием метода разделения переменных или метода Фурье показало, что амплитуда электромагнитной волны значительно уменьшается, пройдя половину толщины образца, что отвечает высоким радиопоглощающим свойствам исследуемых Ni–Zn ферритов. Проведен численный анализ отражения плоской поляризованной волны от двухслойной структуры Ni–Znферрит/металлическая пластина в области частот до 100 MГц. Результаты моделирования верифицированы экспериментальными данными по радиопоглощающим свойствам Ni–Zn ферритов марки 1000НН. Показано, что использование предположения об экспоненциальном характере зависимостей диэлектрической и магнитной проницаемости от нормированной координаты применимы только в узком частотном диапазоне до 3 МГц, для которого экспериментальные данные и результаты численного анализа находятся в хорошем согласии.
ЭВОЛЮЦИЯ СТРУКТУРЫ ПОРОШКОВОЙ СМЕСИ СОСТАВА Ti+Al В ПРОЦЕССЕ МЕХАНИЧЕСКОЙ АКТИВАЦИИ
Authors: Филимонов В.Ю. , Логинова М.В. , Собачкин А.В. , Ситников А.А. , Яковлев В.И. , Мясников А.Ю. , Розный А.А.
Published: September 2023

В представленной работе проведено изучение эволюции структуры механически активированной порошковой смеси состава Ti+Al при продолжительности процесса активации 3, 10, 17 мин. В качестве активатора использовалась планетарная шаровая мельница АГО-2 с двумя цилиндрами. Объем каждого цилиндра составлял 160 см3, диаметр шаров 8 мм, масса порошка в каждом цилиндре 10 г, масса шаров 200 г. Центробежное ускорение цилиндров составляло 400 мс-2 (40 g). Исследования микроструктуры активированных смесей проводились с использованием сканирующего электронного микроскопа SEM S-3400N Hitachi Science Systems Ltd на основе модуля HyperMAP оригинального программного обеспечения. Анализ активированных смесей проводился на дифрактометре ДРОН-6, с CuK-излучением (λ=1,5418 Å). Шаг сканирования составлял 0,05°, время экспозиции – 3 с. В процессе анализа микроструктур выявлено, что активированная смесь характеризуется элементом структуры, представляющим собой пластичную матрицу алюминия с внедренными частицами титана (механокомпозит). Для каждого интервала времени механической активации проводился дисперсный анализ активированной порошковой смеси с целью построения гистограмм распределения как по размерам частиц механокомпозита, так и по размерам частиц титана, распределенных в объеме матрицы. Установлено, что на первой стадии активации наблюдается рост размеров механокмпозитов, на второй стадии доминирует процесс измельчения, что связано с конкуренцией процессов разрушения и агломерации. Размер частиц титана в матрице при этом монотонно уменьшается. Анализ дифрактограмм процесса позволил установить, что основные изменения структуры кристаллической решетки компонентов размола происходят на ранних стадиях процесса механической активации, при этом соединений на основе титана и алюминия не обнаружено для всех времен активации.
ОСОБЕННОСТИ АКУСТИКО-ЭЛЕКТРИЧЕСКИХ МЕТОДОВ МОНИТОРИНГА РАЗРУШЕНИЯ ТВЕРДЫХ ДИЭЛЕКТРИКОВ
Authors: Беспалько А.А. , Данн Д.Д. , Ло Ц. , Федотов П.И.
Published: September 2023

В статье представлены результаты исследований характеристик и параметров механико- и акустико-электрических преобразований. Изучены закономерные связи характеристик электромагнитной эмиссии и параметров электромагнитных сигналов при образовании трещин и наличия слоистости структуры твердотельных диэлектрических материалов при детерминированном импульсном акустическом воздействии. Приведены экспериментальные результаты влияния зарядового состояния слоистых структур на параметры электромагнитных сигналов. На примере сложной структуры неметаллических образцов горных пород приведены закономерности изменений характеристик электромагнитной эмиссии. Используя эти закономерности, показана возможность определять этапы развития разрушения при непрерывном одноосном нагружении сжатием до разрушения образца, в том числе этап образования и развития деструктивной зоны. Изучены закономерности изменения параметров акустико-электрических преобразований при внешних детерминированных импульсных воздействиях на исследуемые естественные и модельные диэлектрические структуры при ступенчатом нагружении одноосным сжатием. Анализируются особенности каждого из используемых методов применительно к контролю процессов развития разрушения.
ПОЛУЧЕНИЕ ФРАГМЕНТИРОВАННОЙ СТРУКТУРЫ МИКРО И НАНОУРОВНЯ В ЧИСТОЙ МЕДИ ПОСЛЕ ВОЛОЧЕНИЯ И РКУП
Authors: Землякова Н.В. , Рогачев С.О.
Published: September 2023

В настоящее время представляет интерес возможность получения регламентированной субмикроструктуры меди методом равноканального углового прессования (РКУП). В работе показано изменение структуры субзерен чистой меди размером до 600 нм после интенсивной холодной пластической деформации. Цель работы – показать возможность получения микрофрагментов в регламентированной субструктуре меди на всех этапах холодной интенсивной пластической деформации. Для проведения работ был получен пруток технически чистой меди М1 диаметром 20 мм после холодной (Т = 20 ºС) деформации волочением (исходное состояние). Была проведена интенсивная пластическая деформация прутка методом РКУП по маршруту Bc за 4 и 8 проходов. Изображения субмикроструктуры и электронограмма образцов получены методом просвечивающей электронной микроскопии. В первичных субзернах, полученных после волочения, происходит сначала сдвиг с образованием деформационных дефектов в виде пакета нанодвойников, каждый толщиной 35 нм. Затем уже в объеме образца происходит аккомодационное скольжение, после чего пакеты нанодвойников разрушаются и образуются фрагменты округлой формы размером 100 нм. После четырех проходов РКУП в субзерне диаметром 500 нм были обнаружены фрагментированные микрополосы переориентации шириной от 70 нм и нанофрагменты шириной 20 нм. Отличие субструктуры меди, полученной в ходе интенсивной пластической деформации, состоит в том, что после четырех проходов РКУП присутствуют микрополосы переориентации, а после восьми проходов РКУП в границах и стыках субзерна образовались нанофрагменты диаметром от 35 нм. Микрополосы переориентации формировались под действием дисклинаций, расположенных в стыках и в субзеренных границах субзерна.
РЕИНЖИНИРИНГ ТЕХНОЛОГИИ ПОЛУЧЕНИЯ ОТЛИВОК ИЗ ВЫСОКОХРОМИСТОГО ЧУГУНА ЧХ28
Authors: Гурьев М.А. , Иванов С.Г. , Черных Е.В. , Романенко В.В. , Гурьев А.М.
Published: September 2023

Одной из важнейших задач горнодобывающей, рудо- и лесоперерабатывающей промышленностей является импортозамещение и реинжиниринг деталей зарубежной техники. В настоящей работе с применением принципов реинжиниринга исследуется химический состав и структура отработанной детали дробильного оборудования. Установлено, что представленные образцы выплавлены из высокохромистого чугуна ЧХ28, дополнительно легированного молибденом, ванадием и никелем. Наиболее близким зарубежным аналогом данного материала может быть сталь марки DIN 1695-81: G-260Cr27. Результаты исследования показали, что материал отливок подвергался нагреву до температур 950-1050 °С и выдержке при этих температурах в течение времени не менее 2 ч, с последующим охлаждением на воздухе до температур 160-200 °С и отпуском при температуре 200 °С в течение времени не менее 2 ч, что подтверждается твердостью образцов на уровне 63-64 HRC и высокой степенью равновесности их структурно-фазового состояния и гомогенности фаз.
Hetero-Bimetallic Paddlewheel Complexes for Enhanced CO2 Reduction Selectivity: A First Principles Study
Authors: McCarver Gavin , Yildirim Taner , Zhou Wei
Published: September 2023

The reduction of carbon dioxide (CO2) into value-added feedstock materials, fine chemicals, and fuels represents a crucial approach for meeting contemporary chemical demands while reducing dependence on petrochemical sources. Optimizing catalysts for the CO2 reduction reaction can entail employing first principles methods to identify catalysts possessing desirable attributes, including the ability to form diverse products and exhibit favorable reaction kinetics. In this study, we investigate the CO2 reduction reaction on bimetallic Cu paddlewheel complexes, aiming to understand the impact metal doping has on bimetallic paddlewheel metal-organic frameworks (MOFs). Doping the paddlewheel with Mn results in a more catalytically active Cu center, poised to produce substantial quantities of formic acid (HCOOH) and minor quantities of methane (CH4) with a suppressed production of C2 products. Moreover, the presence of Mn as a dopant significantly reduces the limiting potential for CO2 reduction from 2.22 eV on the homo-bimetallic Cu paddlewheel complex to 1.19 eV, thereby necessitating a smaller applied potential. Conversely, within the Co-doped paddlewheel complex, the Co-site emerges as the primary catalytic center, selectively yielding CH4 as the sole reduced CO2 product, with a limiting potential of 1.22 eV. Notably, the Co site faces substantial competition from H2 production, attributed to a lower limiting potential of 0.81 eV for hydrogen reduction. Our examination of the Cu-Ni paddle-wheel complex, featuring a Ni dopant, reveals two catalytically active centers, each promoting distinct reductive processes. Both the Ni and Cu sites exhibit a propensity for HCOOH formation, with the Ni site favoring further reduction to CH4, while the Cu site directs the reaction towards methanol (CH3OH) production. This highlights the profound influence of metal dopant incorporations on the type and quantity of products generated during CO2 reduction.
Ultraviolet Photodissociation and Collision Induced Dissociation for Qualitative/Quantitative Analysis of Low Molecular Weight Compounds by Liquid Chromatography-Mass Spectrometry
Authors: Giraud Romain , Le Blanc Yves J.C. , Guna Mircea , Hopfgartner Gérard
Published: September 2023

Collision induced dissociation (CID) is the most wildly used fragmentation technique for qualitative and quantitative determination of low molecular weight compounds (LMWC). Ultraviolet photodissociation (UVPD) has been mainly investigated for the analysis of peptides and lipids while only in a limited way for LMWC. A triple quadrupole linear ion trap instrument has been modified to allow ultraviolet photodissociation (UVPD) in the end of the q2 region enabling various workflows with and without data dependent acquisition (DDA) combining CID and UVPD in the same LC-MS analysis. The performance of UVPD, with a 266 nm laser, is compared to CID for a mix of 90 molecules from different classes of LMWC including peptides, pesticides, pharmaceuticals, metabolites, and drugs of abuse. These two activation methods offer complementary fragments as well as common fragments with similar sensitivities for most analytes investigated. The versatility of UVPD and CID is also demonstrated for quantitative analysis in human plasma of bosentan and its desmethyl metabolite, used as model analytes. Different background signals are observed for both fragmentation methods as well as unique fragments which opens the possibility to develop selective quantitative assay with improved sample throughput, in particular for analytes present in different matrices
Features of the course and adverse events risk of coronavirus infection COVID-19 in hematological diseases (data from the CHRONOS19 register for the Primorsky Territory, intermediate stage)
Authors: Talko Angelina V. , Nevzorova Vera A. , Dubov Vitaliy S. , Muzychenko Nikita S. , Gurbanov Eldar R. , Dubov Sergei K. , Beniova Svetlana N. , Simakova Anna I.
Published: September 2023

Aim. To assess the characteristics of the course of coronavirus infection COVID-19 and to determine the risk factors for adverse events in patients of the regional hematological center.
Materials and methods. As part of an observational prospective cohort study, data from 144 medical records of patients in Primorsky Krai with hematological diseases and COVID-19 were analyzed. The data of the developed standardized questionnaire of the CHRONOS19 study were used. The primary endpoint (adverse outcome) was a composite point that included mortality from any cause during the observation period, development of acute respiratory distress syndrome, hospitalization in the intensive care unit, and the need for mechanical ventilation.
Results. A study of the features of the course of COVID-19 in hematological patients showed an increase in the number of adverse events in patients with neoplastic blood diseases, especially in chronic lymphoproliferative diseases and acute myeloid leukemia. Significant predictors of an unfavorable course of COVID-19 include a refractory/recurrent variant of the course of a blood tumor, glucocorticoid therapy as part of the protocol for the treatment of the underlying disease, stage 34 lung damage according to computerised tomography scans at the onset of COVID-19, and the presence of diabetes mellitus.
Conclusion. Predictors of an unfavorable course of COVID-19 in hematological patients have been identified. Hematological patients in the context of the COVID-19 pandemic require a coordinated interdisciplinary approach involving hematologists and therapists, careful monitoring of clinical and laboratory parameters to reduce the risk of adverse events.
Adherence to treatment of hematological malignancies patients with anxiety and depression
Authors: Vybornykh Dmitry E. , Moiseeva Tatiana N. , Gemdzhian Eduard G. , Gaponova Tatiana V. , Esina Liubov V. , Kolgaeva Elmira I. , Novikova Daria V.
Published: September 2023

Aim. To establish the features of the influence of anxiety and depressive disorders on treatment adherence, as well as to clarify the factors associated with it in hematologic malignancies patients.
Materials and methods. The study included 117 patients: 51 men and 66 women, aged 19 to 67 years, with Hodgkin's lymphoma 88, acute lymphoblastic leukemia 16 and aplastic anemia 13 patients. Patients were examined by psychiatrist using the Brief Psychiatric Rating Scale, as well as some psychometric methods.
Results. Anxiety-depressive spectrum disorders were detected in 36 (40.9%) patients with Hodgkin's lymphoma and 8 (50%) with acute lymphoblastic leukemia, in the aplastic anemia group there were three (23.1%) of such patients. It was found that the average adherence to treatment was in 2/3 of patients, low and high in the remaining 1/3 of patients. With medium and low adherence to treatment, the risk of adverse events increases by an average of 1.7 times. The adherence to treatment it is significantly higher in patients older than 45 years. Signs of depression that negatively correlated with adherence to treatment were pessimism and disruption of social ties. Adherence to treatment significantly positively correlates with the following types of attitudes towards the disease: anosognosic, hypochondriac and egocentric, and significantly negatively correlates with the following types of attitudes towards the disease: anxious, melancholic and dysphoric.
Conclusion. Anxiety/depressive disorders contribute to reduced adherence of hematologic malignancies patients to treatment. Their correction and increased adherence should be carried out jointly by hematologists and mental health professionals.
Iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia. Case report
Authors: Mozdon Maria A. , Ponomarev Rodion V. , Tsvetaeva Nina V. , Shabrin Aleksey V. , Ermachenkova Evgeniya I. , Larichev Sergei E. , Lukina Elena A.
Published: September 2023

RenduOslerWeber disease or hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant disease. It is characterized by vascular dysplasia with the formation of telangiectasias on the skin, mucous membranes of the respiratory and digestive tracts, arteriovenous malformations (AVMs) in the internal organs, which is manifested by bleeding. Diagnosis is based on Curacao criteria: recurrent and spontaneous nosebleeds, multiple telangiectases on the characteristic localizations, AVMs in one or more of the internal organs, a family history of HHT (i.e. first-degree relative who meets these same criteria for definite HHT). Therapy is aimed at preventing and stopping gastrointestinal, nosebleeds, correction of iron deficiency anemia. A promising method of therapy is the use of angiogenesis inhibitors, in particular bevacizumab. The article presents a description of a clinical case of HHT in a 49-year-old woman with telangiectisia on the mucous membrane of the tongue, gastrointestinal tract and liver AVMs.
Efficacy of dupilumab in real practice in the treatment of severe forms of asthma and atopic dermatitis (comparative retrospective study)
Authors: Fomina Daria S. , Fedosenko Sergey V. , Bobrikova Elena N. , Chernov Anton A. , Mukhina Olga A. , Lebedkina Marina S. , Karaulov Alexander V. , Nurtazina Asel Yu. , Lysenko Mariana A.
Published: September 2023

Background. Dupilumab, a fully human monoclonal antibody directed against the common -subunit of interleukin (IL)-4 receptors and blocking signaling from both IL-4 and IL-13, may be recommended for the treatment of moderate to severe atopic dermatitis (AD) and bronchial asthma (BA).
Aim. To perform a comparative assessment of the effectiveness of maintenance therapy with dupilumab in patients with severe BA as the main indication for genetically engineered biological drugs and in patients with severe asthma with concomitant severe AD as the indication for targeted therapy.
Materials and methods. A 6-month retrospective comparative study was performed at the specialized reference center for allergology and immunology. The study included 115 adult patients of both sexes treated with dupilumab for uncontrolled severe asthma as the main indication for targeted therapy (BA group; n=65) or for a combination of severe uncontrolled asthma and severe AD (BAAD; n=50). Dupilumab was administered subcutaneously for 6 months. The first dose was 600 mg once and then 300 mg Q2W. Evaluation of the effectiveness of dupilumab therapy at 6 months of treatment in both groups included achieving asthma control (ACT, ACQ5), improving pulmonary function test, reducing the risk of exacerbations and the need for systemic glucocorticosteroids (SGCS), improving quality of life (AQLQ), change of biomarkers (FeNO, eosinophil count) and the course of comorbid diseases, including improvement in the AD (SCORAD, EASI) and rhinosinusitis polyposa (SNOT-22).
Results and conclusion. During dupilumab therapy, in a significant proportion of patients, regardless of the presence or absence of other T2-associated diseases (e.g., AD or rhinosinusitis polyposa), an improvement in asthma was demonstrated as early as in the first 6 months of treatment with dupilumab in all recommended domains for assessing the response to targeted therapy: improving asthma control and respiratory function, reducing the frequency of moderate and severe exacerbations associated with the use of SGCS and/or hospitalization, a positive effect on the quality of life and the comorbid diseases, as well as a cumulative reduction in the need for SGCS.
A call from early‑career Turkish scientists: seismic resilience is only feasible with “earthquake culture”
Authors: Karasözen Ezgi , Büyükakpınar Pınar , Ertuncay Deniz , Havazlı Emre , Oral Elif
Published: September 2023

Despite significant scientific advances in earthquake research and building codes, Türkiye remains vulnerable to earthquakes, as demonstrated by the tragic Kahramanmaraş earthquake in February 2023. In contrast, countries such as Chile and Japan have successfully reduced earthquake damage through strict enforcement of building codes and effective public awareness campaigns. This paper highlights the need for seismic resilience in Türkiye and proposes actionable guidelines to bridge the gap between science and society. These guidelines include comprehensive geoscience education, the establishment of local earthquake centers, effective science communication, preparation for future earthquakes through scenario modeling, and development of an earthquake culture. Geoscience education should be integrated into the education system, and opportunities for geoscientists should be increased. Local earthquake centers can improve seismic monitoring, research, and public outreach. Geoscientists should prioritize science communication training to engage the public and combat misinformation. Scenario modeling and annual preparedness exercises can improve earthquake preparedness across the country, and promoting earthquake memory and awareness initiatives will build a collective consciousness about earthquakes. By implementing these guidelines, Türkiye can build earthquake resilience and mitigate the impact of future earthquakes; however, the active engagement of scientists, institutions, and the public is essential to achieve earthquake resilience.