Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases
Authors: Duse Marzia , Santamaria Francesca , Verga Maria Carmen , Bergamini Marcello , Simeone Giovanni , Leonardi Lucia , Tezza Giovanna , Bianchi Annamaria , Capuano Annalisa , Cardinale Fabio , Cerimoniale Giovanni , Landi Massimo , Malventano Monica , Tosca Mariangela , Varricchio Attilio , Zicari Anna Maria , Alfaro Carlo , Barberi Salvatore , Becherucci Paolo , Bernardini Roberto , Biasci Paolo , Caffarelli Carlo , Caldarelli Valeria , Capristo Carlo , Castronuovo Serenella , Chiappini Elena , Cutrera Renato , De Castro Giovanna , De Franciscis Luca , Decimo Fabio , Iacono Iride Dello , Diaferio Lucia , Di Cicco Maria Elisa , Di Mauro Caterina , Di Mauro Cristina , Di Mauro Dora , Di Mauro Francesco , Di Mauro Gabriella , Doria Mattia , Falsaperla Raffaele , Ferraro Valentina , Fanos Vassilios , Galli Elena , Ghiglioni Daniele Giovanni , Indinnimeo Luciana , Kantar Ahmad , Lamborghini Adima , Licari Amelia , Lubrano Riccardo , Luciani Stefano , Macrì Francesco , Marseglia Gianluigi , Martelli Alberto Giuseppe , Masini Luigi , Midulla Fabio , Minasi Domenico , Miniello Vito Leonardo , del Giudice Michele Miraglia , Morandini Sergio Renzo , Nardini Germana , Nocerino Agostino , Novembre Elio , Pajno Giovanni Battista , Paravati Francesco , Piacentini Giorgio , Piersantelli Cristina , Pozzobon Gabriella , Ricci Giampaolo , Spanevello Valter , Turra Renato , Zanconato Stefania , Borrelli Melissa , Villani Alberto , Corsello Giovanni , Di Mauro Giuseppe , Peroni Diego 
Published: April 2021

Background

In 2019, a multidisciplinary panel of experts from eight Italian scientific paediatric societies developed a consensus document for the use of inhaled corticosteroids in the management and prevention of the most common paediatric airways disorders. The aim is to provide healthcare providers with a multidisciplinary document including indications useful in the clinical practice. The consensus document was intended to be addressed to paediatricians who work in the Paediatric Divisions, the Primary Care Services and the Emergency Departments, as well as to Residents or PhD students, paediatric nurses and specialists or consultants in paediatric pulmonology, allergy, infectious diseases, and ear, nose, and throat medicine.

Methods

Clinical questions identifying Population, Intervention(s), Comparison and Outcome(s) were addressed by methodologists and a general agreement on the topics and the strength of the recommendations (according to the GRADE system) was obtained following the Delphi method. The literature selection included secondary sources such as evidence-based guidelines and systematic reviews and was integrated with primary studies subsequently published.

Results

The expert panel provided a number of recommendations on the use of inhaled corticosteroids in preschool wheezing, bronchial asthma, allergic and non-allergic rhinitis, acute and chronic rhinosinusitis, adenoid hypertrophy, laryngitis and laryngospasm.

Conclusions

We provided a multidisciplinary update on the current recommendations for the management and prevention of the most common paediatric airways disorders requiring inhaled corticosteroids, in order to share useful indications, identify gaps in knowledge and drive future research.