bluuebunny/crossref_metadata_2025 huggingface dataset:
PROSPECTIVA ECOGERENCIAL EN LA GESTIÓN PÚBLICA DE DESECHOS SÓLIDOS EN LA UNIVERSIDAD CENTRAL DE VENEZUELA, PARA PRODUCIR ABONO ORGÁNICO
Authors: Carolla Carmen
Published: January 2025

Las organizaciones deben brindar resultados frente a los requerimientos sociales, económicos y ambientales, en cuanto al manejo de los desechos sólidos generados en sus actividades, de manera que les permita promover el desarrollo sostenible. En esta investigación cualitativa se generó, una manera de organizar y representar los hechos conceptualmente, en red de relaciones de sus partes constituyentes, a través de un proceso de análisis empleando el software ATLAS. ti 2022. La información permitió generar una teorización prospectiva ecogerencial, con el propósito de constituir una visión de futuro posible y deseable, donde el desempeño organizacional considere el manejo de los desechos sólidos y se emplee la fracción orgánica para elaborar abono. Esto incorporando una herramienta estadística disponible, para realizar la gestión pública de los desechos sólidos producidos en los cafetines de la Universidad Central de Venezuela. Se propone materializar la teorización a través del modelo propuesto, empleando estrategias gerenciales, de liderazgo, administrativas y académicas para optimizar los procesos de planificación, dirección, organización, ejecución, evaluación, control y seguimiento, con visión de futuro (prospectiva) en la gestión pública de los desechos sólidos en la institución y así contribuir en la generación de una cultura organizacional diferente.
EVALUACIÓN DEL DESEMPEÑO ANALÍTICO Y RENDIMIENTO EN LA IDENTIFICACIÓN Y CUANTIFICACIÓN DE LOS ELEMENTOS FORMES DE LA ORINA DEL AUTOANALIZADOR FUS-2000
Authors: Hernández Celsy , Ramos Jonattan , Díaz Kelyn , Blanco Gabriela , Martínez William , Cruz Norelys , MENDOZA MARIA JOSÉ
Published: January 2025

el FUS-2000 es un autoanalizador de orina basado en el principio de citometría de flujo laminar hidrodinámica y microscopia digital inteligente automatizada. El presente estudio tuvo como objetivo evaluar el primer autoanalizador FUS-2000 de DIRUI industrial Co, Ltd (China), comercializado en nuestro país. Métodos: investigación descriptiva transversal, que evaluó los parámetros de desempeño analítico de acuerdo a las pautas de DIRUI y los requisitos del CLSI, y el rendimiento para la identificación y cuantificación de los elementos formes mediante el análisis de 209 muestras de orina patológicas de forma ciega por el FUS-2000 y el método manual estandarizado, de acuerdo a los requisitos y recomendaciones de CLSI y EFLM. Resultados: El desempeño analítico para la tasa de arrastre (0,02%), veracidad (sesgo 3,6%), precisión intracorrida (CV 6,62% y 2,97%), e intercorrida (CV 2,74%), cumplió con los requisitos establecidos por el fabricante y resultó relativamente mejor al obtenido por otros autores para otros autoanalizadores. Adicionalmente, el rendimiento para la identificación y cuantificación de los elementos formes mostró una concordancia estadística con coeficiente kappa ponderado óptimo para leucocitos (0,906) cilindros hialinos (0.906) y espermatozoides (1,000); y satisfactorio para glóbulos rojos (0,853), células epiteliales escamosas (0,847), células epiteliales transicionales (0,756), bacterias (0,834) y mucina (0,893). Conclusiones: El FUS-2000 es un autoanalizador con elevado desempeño y rendimiento analítico, que trabaja de forma rápida y con muy baja tasa de revisión manual, lo que mejora la productividad y toma de decisión clínica oportuna, principalmente en laboratorios clínicos que manejan grandes volúmenes de muestras.
Performance Monitoring Model to Increase Employee Productivity at STMIK Mardira Indonesia
Authors: Sudiryo  , Rohendi A , Hidayat Dasrun
Published: January 2025

Performance monitoring is an important point for realizing the progress of a company. Effective performance monitoring is by conducting performance assessments of employees. Employee performance is always faced with the problem that employees do not have work achievement targets or Employee Work Targets (SKP). This research aims to find a performance monitoring model that can be applied at STMIK Mardira Indonesia. The research methodology used is a qualitative method with a case study approach and natural observation. The performance monitoring model that is suitable to be implemented at STMIK Mardira is a combination of Traditional Assessment, Management By Objective (MBO), 360-Degree Feedback models supported by a digital-based information system, namely the Human Resource Information System (HRIS).
Influence of Lifestyle and Prices Regarding Purchasing Decisions at UD Putra TS Majalengka
Authors: Wawan Yuswanto  , Emi Amelia  , Dea Siska Paramita
Published: January 2025

Lifestyle is one of the driving factors for someone to make purchasing decisions. Apart from lifestyle, price and product quality are also influences in purchasing decisions. So it is very important for marketers to understand and study consumer behavior to create sales strategies. This research aims to determine the influence of lifestyle and price both partially and simultaneously on purchasing decisions at UD Putra TS Majalengka.The method used in this research is a descriptive and verification research method with a sample of 96 people who are consumers who come to the UD Putra TS Majalengka, and uses multiple linear regression analysis to determine the mathematical model, product moment (Pearson) correlation analysis , to calculate the level of the closeness of the relationship of determination analysis to determine the effect. To make data processing easier, the author uses SPSS for window software version 25.0.The results obtained show that lifestyle and price have a very strong and positive relationship with purchasing decisions, namely with a correlation of 0.801, while the magnitude of the influence on purchasing decisions is 64.2% as measured using the coefficient of determination formula. based on hypothesis testing, lifestyle and price together have a positive and significant effect on purchasing decisions. Because the value of Fcount (83.432) > Ftable (3.09), so H0 is rejected and Ha is accepted.
HUBUNGAN PENGETAHUAN IBU TENTANG MANFAAT PIJAT BAYI DENGAN PELAKSANAAN PIJAT BAYI SECARA MANDIRI DI DESA MEDAN KRIO TAHUN 2023
Authors: Ermita Silvana Putri
Published: January 2025

Pijat bayi merupakan stimulasi taktil yang memberikan efek biokimia danefek fisiologis pada berbagai organ tubuh. Pijat yang dilakukan secara benar danteratur pada bayi diduga memiliki berbagai keuntungan dalam prosest umbuhkembang bayi. Pijat pada bayi oleh orang tua dapat meningkatkan hubunganemosional antara orangtua dan bayi,juga diduga dapat meningkatkan beratbadan Adapun tujuan penelitian ini adalah untuk mengetahui HubunganPengetahuan Ibu tentang manfaat pijat bayi dengan pelaksanaan pijat bayisecara mandiri di desa medan krio tahun 2023.Jenis penelitian ini adalah survei analitik, dengan pendekatan crosssectional. Populasi pada penelitian ini yaitu Pengetahuan Ibu DenganPelaksanaan Pijat Bayi Di Desa Medan Krio. Sampel pada penelitian ini denganmenggunakan accidental Sampling, yaitu sampel dilakukan dengan mengambilkasus atau responden yang kebetulan ada atau tersedia di suatu tempat sesuaidengan konteks penelitian sebanyak 35 orang.Hasil penelitian menunjukkanbahwa mayoritasibu memiliki pengetahuan dengan kategori kurang sebanyak 17orang (48,6%). Dan minoritas ibu yang memiliki pengetahuan baik sebanyak7(20,0%). Mayoritas ibu yang melaksanakan pijat bayi sebanyak 16 orang(54,3%) dan minoritas ibu yang tidak melaksanakan pijat bayisebanyak 19 orang(45,7%). Terdapat hubungan Pengetahuanibudengan pelaksanaan pijat bayi nilaip 0.000< 0,05 sehingga ada hubungan Pengetahuan ibu Dengan Pelaksanaanpijat bayi di Desa Medan Krio Kecamatan Sunggal Kabupaten Deli serdangTahun 2023.Kesimpulan pada penelitian ini yaitu ada hubungan antara Pengetahuanibu tentang manfaat pijat bayi dengan pelaksanaan pijat bayi secara mandiri didesa medan krio Tahun 2023. Disarankan kepada ibu agar selalu ikut sertadalam setiap penyuluhan yang diberikan tenaga kesehatan agar pengetahuanibu dapat bertambah sehingga tindakannya juga bisa menjadi lebih baik.Kata Kunci :Pengetahuan ibu, pelaksanaan pijat bayi secara mandiri
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGANKEJADIAN KEKURANGANENERGI KRONIK PADA IBU HAMIL DI PUSKESMAS SEMULA JADIKOTA TANJUNGBALAITAHUN 2020
Authors: Erlina Esther Rotua Siringoringo
Published: January 2025

Tujuan penelitian ini adalah Untuk mengetahui Faktor-faktor yangberhubungan dengan kejadian Kekurangan Energi Kronik pada ibu hamil diPuskesmas Semula Jadi Kota Tanjungbalai tahun 2020. Penelitian inimenggunakan metode penelitian survey analitik yaitu penelitian yang mencobamenggali bagaimana dan mengapa fenomena terjadi. Populasi dalam penelitianini Populasi dalam penelitian ini adalah seluruh ibu hamil yang melakukankunjungan ke Puskesmas Semula Jadi Kota Tanjungbalai pada bulan Mei 2020sebanyak 35 orang. Analisis data dilakukan dengan uji chi-square.Hasilpenelitian menunjukan bahwa Tidak terdapat hubungan Umur,paritas, dan jarakkehamilan Ibu dengan kejadian Kekurangan Energi Kronik pada ibu hamil diPuskesmas Semula Jadi Kota Tanjungbalai Tahun 2020dan Terdapat hubunganpendidikan dan pendapatan dengan Ibu dengan kejadian Kekurangan EnergiKronik pada ibu hamil di Puskesmas Semula Jadi Kota Tanjungbalai Tahun 2020.Saran bagi tenaga kesehatan untuk lebih meningkatan promosi kesehatantentang pentingnya nutrisi selama kehamilan, dan mengaktifkan kelas ibu hamilserta memberikan pendidikan kesehatan tentang KEK dan factor penyebabnyadan bagi ibu hamil agar lebih rutin memeriksakan kehamilannya dan aktifmengikuti penyuluhan yang dilakukan oleh petugas kesehatan untukmendapatkan informasi sehubungan dengan nutrisi selama kehamilan dan selalumengkonsumsi gizi seimbang dan baik dalam masa kehamilan.Kata Kunci : Kekurangan Energi Kronik(KEK), Hamil
HUBUNGAN PENGETAHUAN IBU TENTANG ASUPAN MAKANAN BERGIZI TERHADAP KEJADIAN STUNTING USIA 1-5 TAHUN DI WILAYAH KERJA PUSKESMAS RAMBUNG TAHUN 2023
Authors: Seri Wahyuni Harahap
Published: January 2025

Stunting adalah kondisi gagal pertumbuhan pada anak (pertumbuhan tubuhdan otak) akibat kekurangan gizi dalam waktu yang lama. Sehingga, anak lebihpendek atau perawakan pendek dari anak normal seusianya dan memilikiketerlambatan dalam berpikir. Umumnya disebabkan asupan makan yang tidaksesuai dengan kebutuhan gizi.Penelitian ini adalah penelitian deskriptif analitik dengan pendekatan crosssectional dengan sampel penelitian adalah ibu yang memiliki anak usia 1-5 tahun diwilayah kerja puskesmas Rambung sebanyak 30 orang dengan menggunakan ujichi-square.Dari hasil penelitian nilai asymsig
Ukrainian Orthodox Church Facing the Challenge of War (February – early June 2022)
Authors: Bureha Volodymyr
Published: January 2025

The article is dedicated to the processes in the Ukrainian Orthodox Church (UOC) during the first three months of the escalation of the Russian-Ukrainian war. The author reconstructs the key events of church life over the course of February-May 2022 and shows that the Primate of the UOC  consistently took a patriotic position, condemning Russian aggression from the first day of the escalation. The Church launched a wide range of humanitarian activities aimed at helping refugees and internally displaced persons and regularly provided assistance to the Armed Forces of Ukraine. To the contrary, the Moscow Patriarch Kirill unequivocally sided with the aggressor, which caused mass indignation among the parish clergy of the UOC and led to a movement calling against commemorating Patriarch Kirill during the service, which eventually developed into calls for the complete separation of the UOC from the Moscow Patriarchate. Consequentially, the most determined part of the clergy (more than 430 people) appealed to the heads of all the autocephalous Churches of the world with a call to bring Patriarch Kirill to the church court. The beginning of the war also caused a noticeable aggravation of state-church relations. Local authorities began to make decisions on banning the activity of UOC communities. An assembly of bishops, clergy, and laity was called by the Holy Synod of the UOC on May 27 in Kyiv, which grew into the UOC Council, which made fundamental changes to the UOC Statute and severed the connection of the UOC with the Moscow Patriarchate. While this constitutes a serious breakthrough for the UOC,, the author concludes that the status of the Ukrainian Orthodox Church can only be fully resolved only after the end of the war.
Research, Development, and Evaluation of a Control System for Electric Traction Drives in Railway Applications
Authors:   , Burenin Vsevolod
Published: January 2025

This Thesis aims to develop and validate a control system for railway traction drives using a 2-level inverter and hybrid PWM at low switching frequencies. It includes mathematical solutions for selective harmonic elimination (SHE), a hybrid current observer, and a control system for seamless modulation transitions. Simulations in MATLAB and Simulink, along with laboratory testing on a downscaled prototype, are used to evaluate harmonic distortion, power losses, and system performance under various operating conditions.
Desmoulins vs. Brissot: an episode in the History of French Revolutionary journalism
Authors: Gotovtseva Anastasiya Gennad'evna
Published: January 2025

The article is devoted to one of the episodes in the history of French revolutionary journalism — the polemical confrontation between the leader of the Girondists, J.-P. Brissot, and a supporter of the more radical Montagnard party, C. Desmoulins. The texts of periodicals such as The French Patriot and the Tribune of Patriots, pamphlets by Desmoulins and Brissot, as well as speeches by the Jacobin ideologue Robespierre, are considered. Brissot, attacking the far-left members of the Jacobin Club and the Convention, wrote about the existence among the revolutionaries of a disorganizing party that "wants to destroy everything and build nothing," "a society without a government and a government without power," "not constitutions, but revolutions." Desmoulins, like Robespierre, accused the Girondins of working for the English crown and wanting to create a "federal government", thus dismembering the country, which, in fact, constituted an accusation of high treason. The methodology of the research is complex, which uses general scientific methods of analysis and synthesis, the biographical method, comparative historical and descriptive methods, as well as the method of discursive analysis, which combines the study of linguistic features of the source text and various extralinguistic aspects. The article examines the relationship between legality and revolutionary legal awareness. The revolutionaries abolished the legal norms of the Old Regime and replaced them with an intuitive sense of the danger threatening the Revolution. The verdict was passed not on the basis of actual criminal activity, but on the basis of an inner conviction of the defendant's guilt before the Republic. In his texts against the Brissotines, Desmoulins did not rely on facts proving their guilt or on legal norms, but tried to emotionally arouse hatred of the enemies of the Revolution in his readers. The controversy between Desmoulins and Brissot was based not so much on ideological differences as on a desire to secure a leading position in the National Convention. In this sense, Desmoulins was an expression of the views and political ambitions of the entire Jacobin group, in whose hands Desmoulins' pamphlets were the strongest weapon and contributed to the fall and execution of the Girondists.
The St. Petersburg paradox with state dependent linear utility functions for monetary returns. A note
Authors: Lahiri Somdeb
Published: January 2025

In the experiment underlying the St. Petersburg paradox, we use state-dependent linear utility functions for money with a countably infinite set of states of nature to show that a potential participant will be willing to pay no more than a finite sum of money to participate in the experiment.
Vector properties of angular momentum of cylindrical vector vortex beam in free space
Authors: Gao Yu-Jie  , Li Jin-Hong  , Wang Jing  , Liu Jin-Hong  , Yin Xiao-Jin  ,   1 Shanxi Center of Technology Innovation for Light Manipulations and Applications, School of Applied Science, Taiyuan University of Science and Technology, Taiyuan 030024, China;,   2 Department of Science, Taiyuan Institute of Technology, Taiyuan 030008, China
Published: January 2025

The full vector property of the optical parameter of cylindrical vector vortex beam (CVVB) in free space was characterized using the spin-momentum relation, including the momentum (P), spin angular momentum (SAM), transverse-type spin angular momentum (t-SAM), longitudinal-type spin angular momentum (l-SAM) and light field . P has x, y and z components . SAM has x and y components, but no z component. t-SAM and l-SAM all have components which are parallel and perpendicular to the optical axis when the topological charge m is not 0. t-SAM has a longitudinal component which is related to the helical trajectory of photons and l-SAM has a transverse component in free space. Except for the APVB, which has no longitudinal field when the topological charge m is 0, both RPVB and APVB have longitudinal fields in free space. The vectorial characteristic of the angular momentum of CVVB in free space can provide a theoretical basis for analyzing the transmission of structured beams in different media.
Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida
Authors: He Meina , Tao Yongxin , Mu Kexin , Feng Haoqi , Fan Ying , Liu Tong , Huang Qiaoyun , Xiao Yujie , Chen Wenli
Published: January 2025

Copper is an essential enzyme cofactor in bacteria, but excess copper is highly toxic. Bacteria can cope with copper stress by increasing copper resistance and initiating chemorepellent response. However, it remains unclear how bacteria coordinate chemotaxis and resistance to copper. By screening proteins that interacted with the chemotaxis kinase CheA, we identified a copper-binding repressor CsoR that interacted with CheA in
Pseudomonas putida
. CsoR interacted with the HPT (P1), Dimer (P3), and HATPase_c (P4) domains of CheA and inhibited CheA autophosphorylation, resulting in decreased chemotaxis. The copper-binding of CsoR weakened its interaction with CheA, which relieved the inhibition of chemotaxis by CsoR. In addition, CsoR bound to the promoter of copper-resistance genes to inhibit gene expression, and copper-binding released CsoR from the promoter, leading to increased gene expression and copper resistance.
P. putida
cells exhibited a chemorepellent response to copper in a CheA-dependent manner, and CsoR inhibited the chemorepellent response to copper. Besides, the CheA-CsoR interaction also existed in proteins from several other bacterial species. Our results revealed a mechanism by which bacteria coordinately regulated chemotaxis and resistance to copper by CsoR.
Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage response
Authors: Fan Jiayi , Dhingra Nalini , Yang Tammy , Yang Vicki , Zhao Xiaolan
Published: January 2025

Activation of the DNA damage checkpoint upon genotoxin treatment induces a multitude of cellular changes, such as cell cycle arrest or delay, to cope with genome stress. After prolonged genotoxin treatment, the checkpoint can be downregulated to allow cell cycle and growth resumption. In yeast, downregulation of the DNA damage checkpoint requires the Srs2 DNA helicase, which removes the ssDNA binding complex RPA and the associated Mec1 checkpoint kinase from DNA, thus dampening Mec1-mediated checkpoint. However, it is unclear whether the ‘anti-checkpoint’ role of Srs2 is temporally and spatially regulated to both allow timely checkpoint termination and to prevent superfluous RPA removal. Here we address this question by examining regulatory elements of Srs2, such as its phosphorylation, sumoylation, and protein-interaction sites. Our genetic analyses and checkpoint level assessment suggest that the RPA countering role of Srs2 is promoted by Srs2 binding to PCNA, which recruits Srs2 to a subset of ssDNA regions. RPA antagonism is further fostered by Srs2 sumoylation, which we found depends on the Srs2-PCNA interaction. Srs2 sumoylation is additionally reliant on Mec1 and peaks after Mec1 activity reaches maximal levels. Based on these data, we propose a two- step model of checkpoint downregulation wherein Srs2 recruitment to PCNA proximal ssDNA- RPA filaments and subsequent sumoylation stimulated upon Mec1 hyperactivation facilitate checkpoint recovery. This model suggests that Srs2 removal of RPA is minimized at ssDNA regions with no proximal PCNA to permit RPA-mediated DNA protection at these sites.
Diferencias en la susceptibilidad a germinación de precosecha en quínoa (Chenopodium quinoa Willd) asociadas a genotipo y ambiente
Authors:   , Concha Abayay Belén
Published: January 2025

La quínoa ha ganado relevancia en los últimos años debido a sus beneficios nutricionales y su adaptabilidad al cambio climático, lo que ha impulsado su expansión global. No obstante, esta expansión enfrenta un desafío significativo: la germinación de precosecha (GPC), donde las semillas germinan mientras aún están en la planta, reduciendo su valor comercial. Aunque este fenómeno ha sido ampliamente estudiado en otros cereales, en la quínoa se desconocen los factores que influyen en su susceptibilidad y no se han validado los métodos de evaluación existentes para abordarlo. Con el objetivo de identificar los factores que afectan la GPC en quínoa y evaluar la eficacia de los distintos métodos de evaluación, se estudiaron tres genotipos de quínoa: QLUC05, QLUCNCH y Regalona (variedad comercial), cultivados en condiciones de aire libre e invernadero. Se realizaron pruebas visuales de mojado de panojas en dos estados fenológicos, así como pruebas de germinación para medir la germinación total y el índice de germinación. Los resultados mostraron diferencias significativas entre los genotipos, siendo QLUC05 el más susceptible, seguido de Regalona y QLUCNCH. Además, se observó que el ambiente influye en la dormancia de los genotipos, mostrando mayor dormancia en semillas desarrolladas a temperaturas más altas. Al comparar los métodos de evaluación, se concluyó que es posible detectar diferencias significativas entre los genotipos si se realizan evaluaciones tempranas, lo cual es útil para programas de mejoramiento. QLUCNCH se destacó como un candidato prometedor para reducir el riesgo de GPC en futuros programas de mejoramiento de la quínoa.
De profesor de aula a líder intermedio: tránsito en el ejercicio de la influencia docente, un estudio de caso
Authors:   , García Campaña Maryse
Published: January 2025

La existencia de líderes intermedios bajo la figura de jefes de departamento es fundamental, pues encarnan el puente entre directivos y docentes ejerciendo múltiples funciones tanto como maestro y líder a la vez. Pese a su importancia, existe escasa evidencia sobre el tránsito cuando un profesor asume por primera vez liderar a sus pares. El presente estudio de caso único tiene como objetivo caracterizar la trayectoria de un profesor de aula hacia una posición de liderazgo intermedio desde el departamento de Lenguaje, identificando las prácticas de liderazgo adquiridas, las funciones desarrolladas, las oportunidades, obstáculos y desafíos presentados. Por medio de entrevistas semiestructuradas se realiza un análisis temático cuyos resultados destacan la importancia del conocimiento profundo de la disciplina, el equipo liderado y la influencia de la institución respecto de su empoderamiento como modelo o guía. Se discuten las implicancias sobre las condiciones organizacionales y de desarrollo profesional docente, visibilizando las necesidades y oportunidades que requieren atención para potenciar y facilitar el tránsito de roles.
On the automatic synthesis of modular industrial cyber-physical systems
Authors:   , Biskupovic Mancilla Angel Eduardo
Published: January 2025

Los sistemas ciberfísicos industriales (ICPS) se consideran transversalmente como los sistemas de control industrial del futuro y como una de las tecnologías centrales de la cuarta revolución industrial en curso. A pesar de sus ventajas, los ICPS dependen en gran medida del proceso físico subyacente y su síntesis es un esfuerzo personalizado, exigente en terminos de recursos, que si no se realiza con cuidado puede afectar el rendimiento del sistema. Además, a medida que los ICPS se consolidan como soluciones de automatización maduras, han surgido preguntas sobre cómo aprovechar su flexibilidad para mantener el rendimiento. Este trabajo propone una metodología para abordar la síntesis de ICPS de forma sistemática, mediante el uso de un conjunto de agentes industriales que toman como entrada un archivo de descripción de proceso estandarizado y despliegan automáticamente un ICPS modular a partir de contenedores funcionales prediseñados. La implementacion inicial se demuestra a través de dos ejemplos específicos (un sistema de tanques y un espesador de pasta industrial) para ilustrar el potencial de la metodología propuesta. Los resultados indican que el ICPS puede realizar una síntesis automática independientemente del proceso, facilitada por un archivo de configuración, la utilización de agentes y una librería de componentes con servicios empaquetados en contenedores. Además, el sistema muestra adaptabilidad a diversos requisitos de proceso y puede repararse a sí mismo en caso de una falla del servicio, reduciendo así el tiempo de implementacion y puesta en marcha.Para facilitar el proceso de síntesis, dadas las limitaciones de los estandares industriales actuales para modelar la información, esta tesis propone un modelo de información basado en gráficos multicapa que facilita la tarea de interpretación al agente responsable.También se ha incorporado el concepto de clases y subclases, permitiendo clasificar nodos y relaciones en función de su apariencia y rol dentro del ICPS. El modelo incluye capas que clasifican los componentes del proceso en cuatro aspectos esenciales: red, lógico, físico y nube.Finalmente, la tesis concluye integrando tareas de toma de decisiones para mejorar el desempeño, la eficiencia y otros aspectos operativos del ICPS a través de un conjunto de agentes supervisores. Se realizaron pruebas en dos estudios de caso, que demostraron que el uso de agentes industriales para monitorear y reconfigurar los servicios del ICPS mejoró el desempeño de ambos sistemas propuestos.
Exploring the Role of ChatGPT in Transforming the Education Ecosystem
Authors: Mo Zimei
Published: January 2025

Since its emergence, ChatGPT has emerged as a transformative technology with significant implications for the education ecosystem. This paper discusses the author's attitude towards ChatGPT through three aspects: assessing the potential it brings to the educational ecosystem (including its impact on learners, educators, and the educational system), how educational focus will adapt to the times, and by examining the reasons for the integration of ChatGPT into educational applications through the context of early childhood education, which is the starting point of school education. The challenge of how education adapts to and leads the development of the times is always a difficult issue. The focus of this paper is still centered around the "essence of education". Regardless of the emergence of new methods, the ultimate goal of education is to cultivate individuals with sound physical and mental development
The Impact of Corporate Governance on Firm Performance: A Review
Authors: Ilahiyah Mar'a Elthaf , Yahya Dian Ratnasari , Yahya  , Triyonowati  , Khan Muhammad Arsalan , Palupi Dian
Published: January 2025

Aims: The purpose of this paper is to analyze the results of recent empirical research on the impact of corporate governance on firm performance and reflect on potential research design issues that lead to inconsistent results.
Study design: Literature Review.
Place and Duration of Study: Archival Literature from Emerald Journal’s Data.
Methodology: This study aims to explore the impact of financing decisions on firm value in Indonesia, focusing on the implementation of Good Corporate Governance (GCG). This study synthesizes existing studies by collecting data from scientific literature sourced from online databases such as Google Scholar, Mendeley, and others. The literature review includes articles published in the last decade (2020-2024).
Results: Empirical evidence shows that financing decisions positively and significantly affect firm value. Optimal financing choices can increase firm value sustainably. In addition, the implementation of GCG principles is essential in overseeing management practices, ensuring transparent, responsible, and shareholder-friendly financing decisions.
Conclusion: This study provides in-depth insights into the relationship between financing decisions, firm value, and the importance of GCG practices in the Indonesian business environment.
Navigating Ethics and Regulation: The Role of AI in Modern Financial Services
Authors: Al-Harbi Ahmad
Published: January 2025

In this paper, I delve into the ethical and regulatory aspects of using artificial intelligence (AI) in the finance sector. As AI technologies increasingly influence financial decision-making, addressing issues of fairness, transparency, and regulation becomes crucial. The research will involve reviewing relevant academic literature, industry reports, and regulatory documents to gather information and insights on the ethical and regulatory dimensions of AI in finance. My research focuses on three main areas: the presence of bias in AI-driven financial decisions, the regulatory challenges hindering ethical AI deployment, and the need for transparency and explainability in AI processes. By examining these aspects, I argue that mitigating bias, enhancing regulatory frameworks, and promoting clarity in AI applications are essential for building trust and ensuring ethical practices in financial services. Key findings include the presence of bias in AI-driven financial decisions, the need for updated regulatory frameworks to address AI complexities, and the importance of transparency and explainability in AI processes. These elements are crucial for building trust and ensuring ethical practices in financial services. Ultimately, this work advocates for a collaborative approach among regulators, financial institutions, and AI developers to create a more equitable financial ecosystem.
Hydrochemical Assessment of Water Quality and Risks Related to the Use of Groundwater Resources in the Urban Area of Niamey and Nearby Rural Areas in the Regions of Dosso and Tillabery in Niger
Authors: Mohamed MOUNKAILA , Zeinabou MAHAMADOU , Abdoulatif ABASS SALEY , Moussa RABILOU SOULEY , Maman INOUSSA Maarouhi , Salifou SOUMANA
Published: January 2025

Groundwater continues to be useful as the main source of drinking water in semi-arid and arid regions of sub-Saharan Africa. The main goal of this work is to assess the health risks associated to the consumption of borehole water in urban and peri-urban areas of Niamey in Niger. Hydrochemical analyses were carried out from water samples of 16 boreholes using standard methods (AFNOR). The parameter measured are pH, Electric conductivity (EC), HCO3-, NO3-, NO2-, Cl-, SO42-, F-, Na+, K+, Ca2+, Mg2+, Fe2+ and Mn2+. 80% of the samples are very risky for the populations. About 56% of boreholes have a nitrate concentration < 30 mg/L and 44% of samples have more than 50 mg/L corresponding the limit standard set by the WHO. High nitrite contents (NO2-) were determined from the same borehole water samples and contain more than 10 mg/L, and are considered unfit. Main causes are the lack of good urban wastes  managements, and the uncontrolled use fertilizers in the agricultural sectors. The sites containing between 2 and 3 mg/L of Fe2+ are located in areas of lateritic soils. About 12% of samples contain Mn2+ above the WHO standard (0.4 mg/L). This study of few boreholes from Niamey and its close rural areas demonstrates that nitrate, nitrite and manganese contents may cause major risks, in particular gastric, cardiovascular, carcinogenic and neurological diseases. With the growing population and urbanization, the lack of sanitation and of good management of urban waste, monitoring of groundwater quality is urgently need to preserve human health. Regular,  rapid and less costly monitoring of the pH and electrical conductivity of urban borehole  waters can help to prevent the risk of poisoning by nitrate, nitrite and by heavy metals such as manganese.
Analysis of Construction Technology of Shear Wall in House Construction
Authors: Gao Yan , Wu Shaojie , Tan Zilong
Published: January 2025

With the increase in economic development and urban construction, the development of the domestic construction industry has further accelerated. In building engineering, shear wall structures are commonly adopted, which can effectively ensure project efficiency. This article first analyzes the shear wall structure in building construction, then introduces the application of shear wall construction technology in house construction, including reinforcement construction technology, formwork construction technology, and concrete construction technology, and finally proposes key points for maintaining construction quality, hoping to provide effective reference for relevant personnel.
Titanium particles inhibit bone marrow mesenchymal stem cell osteogenic differentiation through the MAPK signaling pathway
Authors: Tong Shunyi , Fang Sanhua , Ying Kangjie , Chen Weiwei
Published: July 2023

Metallic implants have great application in clinical orthopedics. Implants wear out in vivo due to long‐term mechanical loading. The formation of wear debris is one of the long‐term complications of prosthesis. In the case of artificial joint replacement in particular, aseptic loosening is the most common reason for secondary revision surgery. Previous studies suggested that wear debris caused aseptic loosening mainly by promoting osteolysis around the prosthesis. In this study, titanium particles, the most commonly used particles in clinical practice, were selected to simulate wear debris and explore the influence of titanium particles on osteogenic differentiation of mesenchymal stem cells. Our results show that titanium particles can significantly inhibit osteogenic differentiation in a dose‐dependent manner. While engaged in preliminary exploration of the underlying mechanisms, we found that titanium particles significantly affect phosphorylation of ERK1/2, a key component of MAPK signaling. This suggests that the MAPK signaling pathway is involved in the inhibition of osteogenic differentiation by titanium particles.
Super‐priority lien challenged for its state constitutionality in the United States of America
Authors: Nishiura Sadatsugu
Published: July 2023

This note focuses on super‐priority liens (SPLs), which allow homeowner associations to foreclose a property over its mortgage. Twenty‐two states have so far implemented such liens, hoping to balance the interests of mortgage creditors and homeowner associations. The state of Nevada has been facing more challenges from both mortgage creditors and homeowner associations regarding the constitutionality of non‐judicial foreclosure than other states. This paper summaries the cases since 2000 and discusses the three major decisions that the Supreme Court of Nevada made involving SPLs' non‐judicial constitutionality, tender‐extinguishing SPLs, and federal creditors' role in SPLs.
Predictive factors and diagnostic significance of CT findings for anastomotic leak after gastric cancer surgery: A retrospective analysis
Authors: Sah Birendra Kumar , Zhang Yang , Li Jian , Li Chen , Zhang Huan , Yan Min , Zhu Zheng Gang
Published: July 2023

Background

Anastomotic leak following radical gastrectomy poses a significant risk to patients. Despite previous studies, effective methods for diagnosing anastomotic leaks after gastric cancer surgery remain elusive. In this study, we aimed to assess the overall burden of anastomotic leaks and investigate diagnostic factors, particularly radiological signs on postoperative computed tomography (CT), that may facilitate early detection.

Methods

We included a total of 70 gastric cancer patients who underwent curative gastrectomy and underwent CT examination post‐surgery. Among them, 35 patients with anastomotic leak were matched with 35 patients without anastomotic leak. We compared the rates of various types of postoperative complications between the two groups and conducted univariate and multivariate analyses to identify predictive variables for postoperative diagnosis.

Results

Patients with anastomotic leaks experienced significantly longer postoperative hospital stays and higher overall expenditures (p < 0.001). Logistic regression analysis revealed that extraluminal gas at the anastomosis site, fever (T ≥ 38.5°C), and neutrophilia (NE ≥ 78%) on postoperative days 4–7 were independent diagnostic factors for anastomotic leaks (p < 0.05).

Conclusions

The diagnostic factors identified in this study offer valuable insights into early detection of anastomotic leaks. We recommend early CT examination for patients exhibiting consistent fever and neutrophilia between postoperative days 4 and 7 following gastric cancer surgery.
A comprehensive study of skeletal muscle imaging in FHL1‐related reducing body myopathy
Authors: Mohassel Payam , Yun Pomi , Syeda Safoora , Batra Abhinandan , Bradley Andrew J. , Donkervoort Sandra , Monges Soledad , Cohen Julie S. , Leung Doris G. , Munell Francina , Ortez Carlos , Sánchez‐Montáñez Angel , Karachunski Peter , Brandsema John , Medne Livija , Chaudhry Vinay , Tasca Giorgio , Foley A. Reghan , Udd Bjarne , Arai Andrew E. , Walter Glenn A. , Bönnemann Carsten G.
Published: July 2023

Objective

FHL1‐related reducing body myopathy is an ultra‐rare, X‐linked dominant myopathy. In this cross‐sectional study, we characterize skeletal muscle ultrasound, muscle MRI, and cardiac MRI findings in FHL1‐related reducing body myopathy patients.

Methods

Seventeen patients (11 male, mean age 35.4, range 12–76 years) from nine independent families with FHL1‐related reducing body myopathy underwent clinical evaluation, muscle ultrasound (n = 11/17), and lower extremity muscle MRI (n = 14/17), including Dixon MRI (n = 6/17). Muscle ultrasound echogenicity was graded using a modified Heckmatt scale. T1 and STIR axial images of the lower extremity muscles were evaluated for pattern and distribution of abnormalities. Quantitative analysis of intramuscular fat fraction was performed using the Dixon MRI images. Cardiac studies included electrocardiogram (n = 15/17), echocardiogram (n = 17/17), and cardiac MRI (n = 6/17). Cardiac muscle function, T1 maps, T2‐weighted black blood images, and late gadolinium enhancement patterns were analyzed.

Results

Muscle ultrasound showed a distinct pattern of increased echointensity in skeletal muscles with a nonuniform, multifocal, and “geographical” distribution, selectively involving the deeper fascicles of muscles such as biceps and tibialis anterior. Lower extremity muscle MRI showed relative sparing of gluteus maximus, rectus femoris, gracilis, and lateral gastrocnemius muscles and an asymmetric and multifocal, “geographical” pattern of T1 hyperintensity within affected muscles. Cardiac studies revealed mild and nonspecific abnormalities on electrocardiogram and echocardiogram with unremarkable cardiac MRI studies.

Interpretation

Skeletal muscle ultrasound and muscle MRI reflect the multifocal aggregate formation in muscle in FHL1‐related reducing body myopathy and are practical and informative tools that can aid in diagnosis and monitoring of disease progression.
Advanced Fabrication of Mechanical Metamaterials Based on Micro/Nanoscale Technology
Authors: Chen Zhaochang , Lin Ying-Tian , Salehi Hadi , Che Zhumei , Zhu Ye , Ding Jun , Sheng Biyun , Zhu Ronghua , Jiao Pengcheng
Published: July 2023

In recent years, mechanical metamaterials have shown good mechanical properties such as ultralightness, programmable stiffness, and tunable Poisson's ratio through clever structural design of microstructures. Micro/nanotechnology has been used to ensure mechanical metamaterials’ fabrication quality and performance for use as structural substrates in multifunctional applications. Mechanical metamaterials are intentionally engineered with periodic microstructures in diverse shapes, allowing for the creation of complex structural substrates. However, this sophisticated design poses significant challenges in the fabrication process, particularly at the micro/nanoscale level, where current technology hinders mechanical metamaterials’ performance improvement and function realization. This review explores the fabrication processes of mechanical metamaterials using micro/nanotechnology and showcase recent progress and future trends. Particular attention is given to recent development, challenges, and future trends in advanced fabrication technologies for mechanical metamaterials. This survey aims to explain why mechanical metamaterials have significant benefits and are well‐suited as structural substrates for multifunctional applications, what advanced fabrication technologies at the micro/nanoscale have been introduced to prepare mechanical metamaterials and how to overcome manufacturing technology bottlenecks of mechanical metamaterials in terms of synthesis, materials, and design method.
Bioconjugation in Materials Science
Authors: Bednarek Christin , Schepers Ute , Thomas Franziska , Bräse Stefan
Published: July 2023

With the advent of bioconjugation chemistry in the last two decades, highlighted by the Nobel Prize 2022, the quest for possible novel applications has been greatly intensified, broadening the prospects of these mostly simple, specific, and high‐yield reactions. The advancement of bioconjugation methods is anticipated to expand the scope of bioinstructive and bioadaptive materials science in the future. This perspective article will discuss the reactions developed in this research area over the last 10 years for coupling various biological entities such as polysaccharides, oligonucleotides, peptides, and proteins. Building on this, the impact of bioconjugation reactions in materials science and 3D printing, including their challenges and requirements is shown. Established procedures for modifying molecular structures such as Covalent and Metal Organic Frameworks (COF/MOF) or hybrid materials for biomedical applications and the scope for future research and optimization will be presented.
Biomanufacturing of 3D Tissue Constructs in Microgravity and their Applications in Human Pathophysiological Studies
Authors: Ren Zhanping , Harriot Anicca D. , Mair Devin B. , Chung Michael K. , Lee Peter H. U. , Kim Deok‐Ho
Published: July 2023

The growing interest in bioengineering in‐vivo‐like 3D functional tissues has led to novel approaches to the biomanufacturing process as well as expanded applications for these unique tissue constructs. Microgravity, as seen in spaceflight, is a unique environment that may be beneficial to the tissue‐engineering process but cannot be completely replicated on Earth. Additionally, the expense and practical challenges of conducting human and animal research in space make bioengineered microphysiological systems an attractive research model. In this review, published research that exploits real and simulated microgravity to improve the biomanufacturing of a wide range of tissue types as well as those studies that use microphysiological systems, such as organ/tissue chips and multicellular organoids, for modeling human diseases in space are summarized. This review discusses real and simulated microgravity platforms and applications in tissue‐engineered microphysiological systems across three topics: 1) application of microgravity to improve the biomanufacturing of tissue constructs, 2) use of tissue constructs fabricated in microgravity as models for human diseases on Earth, and 3) investigating the effects of microgravity on human tissues using biofabricated in vitro models. These current achievements represent important progress in understanding the physiological effects of microgravity and exploiting their advantages for tissue biomanufacturing.
Global Literature Analysis of Organoid and Organ‐on‐Chip Research
Authors: Shoji Jun‐ya , Davis Richard P. , Mummery Christine L. , Krauss Stefan
Published: July 2023

Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical, physiological, or pathological states of tissues and organs. These technologies are widely regarded by academia, the pharmacological industry and regulators as key biomedical developments. To map advances in this emerging field, a literature analysis of 16,000 article metadata based on a quality‐controlled text‐mining algorithm is performed. The analysis covers titles, keywords, and abstracts of categorized academic publications in the literature and preprint databases published after 2010. The algorithm identifies and tracks 149 and 107 organs or organ substructures modeled as organoids and organ‐on‐chip, respectively, stem cell sources, as well as 130 diseases, and 16 groups of organisms other than human and mouse in which organoid/organ‐on‐chip technology is applied. The analysis illustrates changing diversity and focus in organoid/organ‐on‐chip research and captures its geographical distribution. The downloadable dataset provided is a robust framework for researchers to interrogate with their own questions.
Long Lifetime Delayed Fluorescent Materials with Water and Temperature Tolerability Based on Charge Separation States
Authors: Lu Peng , Zhou Mengdie , Gu Danyu , Yuan Yongjie , Yu Yan , Zhang Hailiang
Published: July 2023

Long lifetime delayed fluorescent materials have great potential applications in bioimaging, anti‐counterfeiting encryption, lighting, and other fields. However, the preparation of functionalized long lifetime fluorescent materials with simple chemical structure and tunable luminescent behavior still poses significant challenges. In this article, a simple and effective method to prepare a series of long lifetime delayed fluorescent copolymers with temperature and humidity tolerance is presented. This method involves the copolymerization of 2‐bromo‐5‐hydroxybenzaldehyde derivative monomer (M1), which contains electron‐withdrawing groups, with naphthalimide derivative fluorescent monomer (M2), which contains electron‐donating groups. The results demonstrate that long‐range charge transfer occurs between the two components in copolymers, forming charge‐separated states that emit long lifetime delayed fluorescence after exciton recombination. The delayed luminescent behavior of the copolymer is directly influenced by the content of the M2 component. The maximum delayed fluorescence lifetime can reach 13.7 ms, and the fluorescence quantum yield is 39%. Interestingly, the polymer film of P3 can emit a maximum afterglow of 1.00 s after photoactivation. Even after being immersed in water for 49 days, the afterglow remains unchanged. Besides, the afterglow of P3 can exist for ≈0.43 s at 323 K. Even at 373 K, the afterglow for 0.2 s can still be observed.