bluuebunny/crossref_metadata_2025 huggingface dataset:
Of Inflammasomes and Alarmins: IL-1β and IL-1α in Kidney Disease
Authors: Anders Hans-Joachim
Published: August 2016

Kidney injury implies danger signaling and a response by the immune system. The inflammasome is a central danger recognition platform that triggers local and systemic inflammation. In immune cells, inflammasome activation causes the release of mature IL-1β and of the alarmin IL-1α. Dying cells release IL-1α also, independently of the inflammasome. Both IL-1α and IL-1β ligate the same IL-1 receptor (IL-1R) that is present on nearly all cells inside and outside the kidney, further amplifying cytokine and chemokine release. Thus, the inflammasome-IL-1α/IL-β-IL-1R system is a central element of kidney inflammation and the systemic consequences. Seminal discoveries of recent years have expanded this central paradigm of inflammation. This review gives an overview of arising concepts of inflammasome and IL-1α/β regulation in renal cells and in experimental kidney disease models. There is a pipeline of compounds that can interfere with the inflammasome-IL-1α/IL-β-IL-1R system, ranging from recently described small molecule inhibitors of NLRP3, a component of the inflammasome complex, to regulatory agency–approved IL-1–neutralizing biologic drugs. Based on strong theoretic and experimental rationale, the potential therapeutic benefits of using such compounds to block the inflammasome-IL-1α/IL-β-IL-1R system in kidney disease should be further explored.
BP Control and Long-Term Risk of ESRD and Mortality
Authors: Ku Elaine , Gassman Jennifer , Appel Lawrence J. , Smogorzewski Miroslaw , Sarnak Mark J. , Glidden David V. , Bakris George , Gutiérrez Orlando M. , Hebert Lee A. , Ix Joachim H. , Lea Janice , Lipkowitz Michael S. , Norris Keith , Ploth David , Pogue Velvie A. , Rostand Stephen G. , Siew Edward D. , Sika Mohammed , Tisher C. Craig , Toto Robert , Wright Jackson T. , Wyatt Christina , Hsu Chi-yuan
Published: August 2016

We recently showed an association between strict BP control and lower mortality risk during two decades of follow-up of prior participants in the Modification of Diet in Renal Disease (MDRD) trial. Here, we determined the risk of ESRD and mortality during extended follow-up of the African American Study of Kidney Disease and Hypertension (AASK) trial. We linked 1067 former AASK participants with CKD previously randomized to strict or usual BP control (mean arterial pressure ≤92 mmHg or 102–107 mmHg, respectively) to the US Renal Data System and Social Security Death Index; 397 patients had ESRD and 475 deaths occurred during a median follow-up of 14.4 years from 1995 to 2012. Compared with the usual BP arm, the strict BP arm had unadjusted and adjusted relative risks of ESRD of 0.92 (95% confidence interval [95% CI], 0.75 to 1.12) and 0.95 (95% CI, 0.78 to 1.16; P=0.64), respectively, and unadjusted and adjusted relative risks of death of 0.92 (95% CI, 0.77 to 1.10) and 0.81 (95% CI, 0.68 to 0.98; P=0.03), respectively. In meta-analyses of individual-level data from the MDRD and the AASK trials, unadjusted relative risk of ESRD was 0.88 (95% CI, 0.78 to 1.00) and unadjusted relative risk of death was 0.87 (95% CI, 0.76 to 0.99) for strict versus usual BP arms. Our findings suggest that, during long–term follow-up, strict BP control does not delay the onset of ESRD but may reduce the relative risk of death in CKD.
Heterogeneity in the Dynamics of Disaggregate Unemployment
Authors: Ahn Hie Joo
Published: August 2016

This paper explores the role that unobserved heterogeneity within an observed category plays in the dynamics of disaggregate unemployment and in the cross-sectional di¤erences across individuals of the duration of unemployment spells. The distribution of unobserved heterogeneity is characterized as a mixture of two distributions with each mean and weight determined by the in ows and out ows of workers with unobserved types H and L, which are identied based on the nonlinear state-space model of Ahn and Hamilton (2016). I found that the contribution of each factor to the dynamics of disaggregate unemployment di¤ers by observed category. The in ow of type L workers is the most important factor in the majority of demographic groups in the business-cycle frequency. I identify permanent job loss to be the observable characteristic most closely associated with the type L attribute. A simple model of heterogeneity based on two unobserved types can explain more than 50 percent of the cross-sectional dispersion in completed-duration spells after the Great Recession, while observed heterogeneity makes only a minor contribution.
Accurate Evaluation of Expected Shortfall for Linear Portfolios with Elliptically Distributed Risk Factors
Authors: Dobrev Dobrislav , Nesmith Travis D. , Oh Dong Hwan
Published: August 2016

We provide an accurate closed-form expression for the expected shortfall of linear portfolios with elliptically distributed risk factors. Our results aim to correct inaccuracies that originate in Kamdem (2005) and are present also in the recent comprehensive survey by Nadarajah, Zhang, and Chan (2014) on estimation methods for expected shortfall. In particular, we show that the correction we provide in the popular multivariate Student t setting eliminates understatement of expected shortfall by a factor varying from at least 4 to more than 100 across different tail quantiles and degrees of freedom. As such, the resulting economic impact in financial risk management applications could be significant. More generally, our findings point to the extra scrutiny required when deploying new methods for expected shortfall estimation in practice.
Energiewende’s Lone Warriors: A Hyperlink Network Analysis of the German Energy Transition Discourse
Authors: Kaiser Jonas , Rhomberg Markus , Maireder Axel , Schlögl Stephan
Published: August 2016

This paper explores the integration of different social fields within the German Energy Transition (Energiewende) discourse in the election year 2013 by analysing the hyperlink structures online. Energiewende describes the fundamental transition from non-renewable energy to sustainable sources. This goal is both ambitious and controversial. Numerous stakeholders try to make their voices and interests heard and as such politics has to both disseminate and collect information in order to include all relevant groups from different social fields in the political process. This discourse is also visible online. By analysing the hyperlink structures we are able to see the attention distribution of different actor groups in the network. This study shows that most actors tend to link within their own social field and do not aim for a more integrated public sphere. Especially political actors appear to be lone warriors who neither look left or right and mostly link within their own party and ignore other actors. Whereas social field as the media or public administration are relevant within the network we find that scientific actors are ignored by all fields, except for their own.
No Digital “Castles in the Air”: Online Non-Participation and the Radical Left
Authors: Andersson Linus
Published: August 2016

This article presents results from a study of online presence in activist milieus associated with the radical left in Sweden discussed from a perspective of non-participation. With the aim to further the understanding of digital non-participation as communicative strategy in activism, it builds upon empirical findings and argues that the online practices and use of social media, as could be observed in milieus associated with the radical left, indicates active non-participation and that this, in turn, is related to the ambition to claim autonomy. The article draws from existing scholarship on critical perspectives on protest movements and social media as well as empirical examples of online content published by radical leftist groups. Furthermore, it analyses how these activities could be understood in terms of active and passive non-participation, abstention or adaptation to social media affordances, as well as implosion of the social in digital media. The findings suggest that much of the activities in the material could be described as active non-participation and that this media practice relates to ideological positioning and values in the milieu.
Scientometric databases and integration of Ukrainian biological journals into common information space
Authors: Torgalo E. , Vakal S. , Ostapchenko L.
Published: August 2016

The most well-known citation indices and scientometric databases are reviewed in the article. Among them are Web of Knowledge, Scopus, Index Copernicus, GoogleScholar, Russian Science Citation Index. Basic concepts of calculation, as well as differences between most widely used scientometric values (IF, h-index, SJR, SNIP, ICV etc.), are explained. Simple methods of search of indexed journals lists and abovementioned scientometric values are depicted. Up-to-date list of Ukrainian biological journals included in international citation indices, as well as their indexation and citation dynamics for the period 1996-2013, are represented. Modern problem of "predatory" journals and possible strategies for increase of Ukrainian journals representation in common informational space are discussed at the end of the paper.
Features of the etythropoesis upon treatment of chronic myeloid leukemia with tyrosine kinase inhibitor
Authors: Sviezhentseva I. , Bilko D. , Bilko N. , Dyagil I.
Published: August 2016

A functional activity of erythroid hematopoietic cells of patients with chronic myeloid leukemia, who were treated with tyrosine kinase inhibitor of the first and second generation was investigated. Samples of bone marrow of patients with resistance to tyrosine kinase inhibitor treatment show an increase of erythroid colonies number provided that there is erythropoietin in the culture medium. Furthermore, it was found that clone cells in culture in vitro acquire the ability to differentiate towards erythroid direction in the absence of a culture medium culturing exogenous erythropoietin when they have a resistance to imatinib and nilotinib. Thus, the determination of proliferative activity of erythroid hematopoiesis level in cultured cells in vitro may serve as an important prognostic factor for the further choice of treatment strategy.
The appearance of molecules of prothrombin origin in blood upon development of atherothrombotic and cardioembolic ischemic stroke
Authors: Raksha N. , Burlova-Vasylieva M. , Torgalo E. , Savchuk O.
Published: August 2016

Increase of molecules of prothrombin origin in patients with atherothrombotic and cardioembolic stroke subtypes had been shown. It was found the presence of protein fractions in the range of molecular weights corresponding to both prothrombin molecules and its degraded forms.
Influence of essential oils and polyhexamethyleneguanidine on black yeast-like fungi Exophiala alcalophila
Authors: Kondratyuk T. , Kalinichenko A.
Published: August 2016

Influence of essential oils of the following plants Rosmarinum officinalis L., Pinus sibirica Du Tour, Abies sibirica Ledeb., Juniperus communis L., turpentine oil, and polyhexamethyleneguanidine (PHMG) on black yeast-like fungi Exophiala alcalophila FCKU 304 was investigated. Disc-diffusion method was used. Level of the antifungal influence on X. alcalophila found to be different for each chemical. 5% PHMG is characterized by the highest fungicide activity. Level of the antifungal activity of essential oils of plants Rosmarinum officinalis, Pinus sibirica and Abies sibirica is similar to 1.5-3 % PHMG activity. The PHMG and essential oil of Rosmarinum officinalis found to cause exchanges of morphometric indices of cells, colony morphology and intensity of budding E. alcalophila what is considered as adaptations of investigated culture of black yeast-like fungus. Furthermore dimorphic transition 'yeasts – mycelium' of E. alcalophila was observed under influence of essential oil of Rosmarinum officinalis.
Effect of different oral doses of glucose on the blood serum content of serotonin in rats
Authors: Yurchenko A. , Konopelniuk V. , Torgalo E. , Savchuk O.
Published: August 2016

The analysis of the effect of different doses of oral glucose content of serotonin in blood serum of rats. The increasing content of serotonin in blood serum of rats with diabetes and with the administration of glucose. The increase in the studied parameters in the serum of the control group of animals under conditions of glucose. It is concluded that glucose has a direct positive effect on the endogenous flow of serotonin into the bloodstream.
Effect of histamine on lipid composition of rat bile
Authors: Athamnah S. , Baranovsky V. , Reshetnik E. , Veselsky S. , Yanchuk P.
Published: August 2016

To investigate the effect of histamine (8 mkg/kg, i/v) on the concentration of lipids in the rats bile. Using the method of thin layer chromatography concentrations of phospholipids, cholesterol and its esters, free fatty acids, triglycerides were determined in the rats bile collected in acute experiments (anesthesia, sodium thiopental, 50 mg/kg). The results were calculated using Statistica 7.0; p<0,05. Histamine increased concentration of phospholipids, cholesterol, its esters and reduced content of free fatty acids and triglycerides in the rats bile. Probably, histamine, acting on transport lipid components in bile effect on its physical and chemical properties and the maintenance of cholesterol in mixed bile micelles. Histamine affects the metabolic conversion and transport of lipids in the liver cells, causing the increase in the concentration of phospholipids, cholesterol and its esters in bile and decrease it in the content of free fatty acids and triglycerides.
Fusion expression of recombinant human beta-defensin-3 and analysis of its biological activity
Authors: Gerashchenko O. , Kovalchuk V. , Boidunik O. , Soldatkina M. , Pogrebnoy P.
Published: August 2016

Human beta-defensins (hBDs) are small cationic antimicrobial peptides with multiple biologic activities. The aim of the study was cloning, expression in E.coli, purification and in vitro analysis of biological activity of recombinant human beta-defensin-3 (rec-hBD-3). hBD-3 cDNA was cloned into pGEX-2T vector, and recombinant plasmid was transformed into E.coli BL21(DE3) cells.
Rec-hBD-3 was expressed in bacterial cells as GST-hBD-3 fusion protein, and purified by 3-step procedure via affine chromatography on glutathione-agarose, cleavage of fusion protein by thrombin, and reverse phase chromatography on Sep-Pack C18. Analysis of biological activity of rec-hBD-3 has shown that the peptide is active against Pseudomonas aeruginosa in micromolar concentrations in radial diffusion test. Rec-hBD-3 did not affect proliferation and viability of cultured human cancer cells of A431, A549, and TPC-1 lines, but was capable to potentiate cytotoxic effects of rec-hBD-2 and docetaxel in vitro.
Modern concepts of the role of platelet receptors in the dynamics of thrombus formation
Authors: Nikolaieva I. , Halenova T. , Savchuk O.
Published: August 2016

The study of molecular and biological aspects of the platelets functioning with the use of biochemical methods, new technologies of cell and molecular biology became the basis for understanding signaling cascades regulating the activation, adhesion and aggregation of these cells. In this review, the general modern information of the role of platelet membrane receptors in physiological and pathological processes of thrombus formation was performed. The possible role of platelet receptors as target of antiagregatory agents was analyzed. Also, new promising areas of searching for effective and specific antithrombotic agents were identified.
Methods of obtaining multipotent stem cells of the placenta in rats
Authors: Svitina G. , Garmanchuk L. , Shabliy V.
Published: August 2016

Placenta is a valuable source of multipotent stem cells (PMSC) widely used for cell therapy. Hence, the most optimal method of PMSC obtaining remains questionable. By methods of explant culturing and enzymatic digestion were obtained PMSC of fetal origin and multipotent features at 4 th passage. Allogeneic rat serum is not favor PMSC establishment and growth, consequently the use is made of fetal bovine serum, that is xenogeneic for cell cultures.
Influence of low chronic exposure on physiological and biochemical properties of three irradiated generations Aspergillus versicolor
Authors: Tugay A. , Tugay T. , Lukashov D.
Published: August 2016

Exposure of chronic radiation on three generation Aspergillus versicolor, which were obtained in the model conditions from two parental strains: A.versicolor 99 with radioadaptive properties isolated from location "Shelter" Chornobyl NPP and A.versicolor 432 – control were characterized. In investigated generation A. versicolor 99 and A. versicolor 432 were found opposite changes of the growth rate (from deceleration to acceleration) under the cultivating in two medium with different content of carbon source, which value was in the range from 60% to 140% (on wort agar) and from 70% to 230% (on depleted nutrients agar) in comparison with non-irradiated generations. In three investigated generations A.versicolor 432 and A.versicolor 99 were found changes in the profile of activity of the antioxidant enzymes superoxidedismutase, catalase, peroxidase, which had wavy like character (except catalase) and high amplitude of oscillation from decreasing to 70% up to an increase to 900 %.
Protein analysis of rat hepatocytes under conditions glutamate-induced obesity and its correction
Authors: Voieikova D. , Stepanova L. , Savchuk O. , Ostapchenko L. , Kondro M.
Published: August 2016

We had characterized low-, medium- and high-molecular protein fractions of hepatocytes under development of glutamate-induced obesity and correction of nanocrystalline cerium dioxide and pioglitazone. Protein fractions were separated by electrophoresis using a 10 % Laemmli SDS-PAGE sodium dodecyl sulfate. Protein hepatocytes change under glutamate-induced obesity: high-protein reduced, and low-protein increased. Changes in hepatocyte proteins are consistent with previously established changes in protein content of hepatocytes under the influence HCD rich in fats and carbohydrates. We had noticed similar changes in protein of hepatocytes under correction cerium dioxide, but compared with glutamate-induced obesity, low proteins were lower. Pioglitazone didn't show a positive effect on hepatocyte proteins that may be associated with short-term administration.
Promoting a Culture of Engaged Scholarship and Mentoring Junior Faculty in the Reappointment, Tenure, and Promotion Process at a ‘Teaching First’ University
Authors: Boehm Lisa Krissoff , Larrivee Linda S.
Published: August 2016

This paper analyzes the processes and outcomes involved with mentoring junior faculty in the reappointment, promotion, and tenure (RPT) process at a comprehensive state university and creating a culture supportive of engaged research. Although the university in this case study is governed by a collective bargaining agreement that prohibits the development of new written policies on RPT, the deans and other academic leaders can promote significant change through cultural means. The article will examine: the place of engaged scholarship within the reappointment, tenure, and promotion processes of the university; the university’s commitment to a cross-institutional research approach; the mentoring of faculty conducting innovative community projects; the university’s recent strategic plan initiative funding of collaborative cross-college and community projects; partnership with the city of Worcester’s Department of Public Health on applied scholarship related to five domains of public health currently establishedas the focus of efforts by the city and the region; and the innovative CitySpeak devised theater project. At this state university, strong leadership helped support a deepening culture of engaged teaching and scholarship and helped faculty negotiate the road of RPT.
Engaged Scholarship: (Re) Focusing on Our Mission
Authors: Kirtman Lisa , Bowers Erica , Hoffman John L.
Published: August 2016

Although the mission statements of most comprehensive teaching institutions of higher education include serving as a resource for the global and local community, the tenure and promotion process typically does not recognize these community partnerships as research endeavors, even when the nature of the work is firmly grounded in sound empirical practice. This paper shares the process a faculty task force undertook to gain consensus and incorporate language on engaged scholarship within the College’s personnel document. The process took four years and included five steps: (a) establish a definition of engaged scholarship grounded in scholarly literature, (b) gather practice-oriented information regarding best practices as well as faculty perceptions of engaged scholarship practice, (c) create policy language for department personnel documents, (d) generate consensus among faculty for the policy language, and (g) submit final documents to the University Personnel committee for approval. The paper concludes with a discussion of implications for policy and practice.
Pediatric forearm fractures with tens: freedom of movements
Authors: Shivanna Shivanna , C. V. Maruthi
Published: August 2016

Background: A prospective analysis of a case series of diaphyseal forearm fractures in children treated with titanium elastic nails is presented.  

Methods: Between 2012 and 2014, 30 children aged 5-15 years with displaced diaphyseal forearm fractures underwent titanium elastic nailing. Both bones were fractured in 25 patients, four fractured only the radius, and one experienced ulna fracture. Eleven candidates had unstable irreducible fractures, 13 had loss of reduction, and six had open fractures. Titanium elastic nails were used to stabilize the fractures. All fractures were immobilized postoperatively with an above-elbow plaster slab for 2 weeks till the swelling is completely resolved followed by encouraging range of motion exercises.

Results: Closed reduction and TENS was successful in 20 cases, including 15 double-bone fractures and five single-bone fractures. Open reduction was completed in four fractures of both bones, and in six single-bone open fractures. Bone union was achieved in all patients at an average of 7 weeks. The ROM of the forearms was evaluated using the Daruwalla grading criteria. Excellent results were reported in 96% without significant complications after a mean follow-up of 20 months.

Conclusions: Titanium elastic nails fixation of pediatric forearm fractures revealed several advantages, a small incision for insertion, a low rate of complications, unhindered bone healing, and good clinical and radiological results thus achieving maximum range of motion at the earliest.
Hailey Hailey disease-a rare case report
Authors: Prateek Kumar , Banwarilal Meena Rinoo , Chaudhary Shyam Sundar , Garg Meenaskhi
Published: August 2016

Hailey-Hailey disease is an autosomal dominant acantholytic disorder relatively uncommon in India. It is characterized by painful, pruritic, foul smelling vesicles and bullous lesions with erosions in intertriginous areas such as the neck, axillae, inframammary areas and groin. The defect in ATPC2 gene leads to calcium channel dysfunction which results in defect in epidermis. Fungal infection, intertrigo, psoriasis, extramammary Paget's disease, acanthosis nigricans, pemphigus vegetans and Darier's disease are some of the dermatosis from which it needs to be differentiated. Histopathology has a key role in diagnosis of Hailey-Hailey disease with characteristic ‘dilapidated brick wall' appearance. Hailey-Hailey disease can be easily misdiagnosed by general physicians due to lack of knowledge of this uncommon disease as it resembles dermatosis involving intertriginous areas. Due to its relapsing and remitting course there is a need to have effective treatment options. We report a case of 45 year old middle aged female who presented with on and off itchy papules & vesicles over right inframammmary region around the umbilicus & medial aspect of right thigh. Skin biopsy revealed a diagnosis of Hailey-Hailey disease. This case is being reported due to its rare occurrence.
Electroshock: On How and Why It Lingers on Long After Insulin Coma Shock and Lobotomy Are Gone
Authors: Breeding John
Published: August 2016

Mid-20th century psychiatry routinely touted and performed a trio of barbarisms on unwitting or unwilling citizens; insulin coma shock, ice pick lobotomy, and electroshock were treatments of choice. In the second half of that century, 2 of the 3 were stopped. Insulin coma shock ended because it became too difficult for even the glamour and mystification of psychiatric propaganda to cover up the fact that this horrific treatment was literally killing too many people. Not long after—despite a Nobel Prize to its founder, Egas Moniz, and a period of fame and notoriety to its main United States practitioner, James Freeman—the severing of people’s frontal lobes by an ice pick through their eye sockets was stopped. The leadership of psychiatrist Peter Breggin was key in forcing a halt to lobotomy. So 2 of this terrible 3 have joined a long history of psychiatric atrocities no longer practiced, yet electroshock somehow endures. The lobotomists have been disgraced, but the shock doctors, including people like Max Fink who infamously declared in 1996 that “ECT is one of God’s gifts to mankind” (as cited in Boodman, 1996), carry on. What are the facts about electroshock, also known as electroconvulsive treatment, or electroconvulsive therapy (ECT)? How and why is it still used today? In this essay, I will explore these questions and provide some answers.
Voice Hearing Interpreted
Authors: Casstevens W. J.
Published: August 2016

This article presents vignettes that reflect ways three individuals integrate voice-hearing experiences into very different belief systems. Differing spiritual belief systems substantially contributed to how voices were identified and welcomed (or not) into lifestyles and interpersonal relationships, demonstrating the unique nature of interpretation and experience. Although none of these individuals view their voices as symptoms of illness, the concept of “coping” does play a role because managing the voices presented at least occasional difficulties for each. Thus, this article concludes with a summary of successful coping strategies that these three individuals developed and used with their voices.
O ENSINO MÉDIO E O TRABALHO DOCENTE: CARACTERÍSTICAS DE MINAS GERAIS
Authors: Melo Savana Diniz Gomes , Cirilo Pauliane Romano , Pinto Samilla Nayara dos Santos
Published: August 2016

Este artigo visa a apresentar uma discussão sobre o Ensino Médio no Brasil, suas características no Estado de Minas Gerais a partir de 2003, e o trabalho docente nessa etapa de ensino. Aborda, também, aspectos das condições de emprego e de trabalho na Rede Estadual de Educação de Minas Gerais. Em termos metodológicos, o presente artigo fundamenta-se em bibliografia da área, em pesquisa documental com foco em legislações de âmbito nacional e estadual acerca do Ensino Médio, em dados secundários produzidos por pesquisa recente. Conclui-se que o Ensino Médio, no Brasil, adquire uma nova orientação rumo à expansão do ensino superior mercantilizado, e que o trabalho docente, para se adequar a esse objetivo, padece de uma precarização ampliada. Também se propõe a continuidade de estudos.
PROGRAMA DE AVALIAÇÃO DA APRENDIZAGEM ESCOLAR (PAAE): INTERFACES PEDAGÓGICAS ENTRE AVALIAÇÃO E CURRÍCULO DE HISTÓRIA NO ENSINO MÉDIO
Authors: Fernandes Alex De Oliveira , Gomes Suzana Dos Santos
Published: August 2016

Este texto visa a contribuir com o debate na área de políticas públicas de avaliação, com dados analisados sobre o Programa de Avaliação da Aprendizagem Escolar (PAAE) e suas interfaces com o Currículo Básico Comum (CBC) da disciplina de História na Rede Pública Estadual de Educação de Minas Gerais. Buscou-se analisar as concepções de avaliação e de ensino-aprendizagem que norteiam o programa, e que estão presentes no CBC. Para tanto, elegeu-se como referencial teórico os autores do campo da avaliação e do currículo. Constatou-se uma convergência entre as concepções de ensino de História presentes na proposta curricular para o Ensino Médio e os itens de teste utilizados pelo programa, assim como a necessidade de pesquisas no interior das escolas, como forma de preencher as lacunas existentes nos debates no campo da avaliação educacional e do currículo.
AS POLÍTICAS PARA O ENSINO MÉDIO NA REALIDADE BRASILEIRA: UMA AGENDA EM DISPUTA
Authors: Oliveira Dalila Andrade
Published: August 2016

O artigo discute a situação do Ensino Médio na atualidade no Brasil, a partir de algumas mudanças vividas na última década. O texto procura discutir a situação do Ensino Médio diante das exigências da legislação recente, mais especificamente a instituição da obrigatoriedade e gratuidade pela EC n° 59/2009 e a aprovação do Plano Nacional de Educação. Procura, ainda, refletir sobre o impacto sofrido no Ensino Médio com as mudanças no Enem, que promoveram uma verdadeira revolução na forma de ingresso à educação superior pública, por meio do Sisu; e privada, em decorrência da vinculação de seu resultado à concessão de bolsas do ProUni, e sobre os efeitos diretos e indiretos desse exame sobre a orientação curricular, que vem sendo dirigida no sentido de responder à exigência do teste.
GESTÃO ESCOLAR E O TRABALHO DOS DIRETORES EM MINAS GERAIS
Authors: Duarte Adriana , Augusto Maria Helena , Jorge Tiago
Published: August 2016

Este artigo busca apresentar quem são os diretores de escolas de Ensino Médio em Minas Gerais e como eles respondem as demandas advindas do chamado Acordo de Resultados estabelecido entre as escolas e os órgãos centrais da educação no estado. Este acordo está voltado para o cumprimento de metas, buscando o alinhamento das políticas educacionais às políticas de governo, com base nos resultados obtidos em sistemas de avaliação do estado e nacionais. Neste processo, não se leva em consideração outros aspectos, como as condições de trabalho das escolas e dos professores, as desigualdades sociais e educacionais existentes, e as peculiaridades de cada região e de cada escola. A avaliação é vista como um mecanismo indutor de excelência e torna-se um mecanismo eficaz de controle e de responsabilização de seus agentes.
A REFORMA DO ENSINO MÉDIO E OS INTERESSES DE MERCADO NA POLÍTICA EDUCACIONAL
Authors: Frizzo Giovanni
Published: August 2016

Ensaio Acadêmico
LA REFORMA DE LA ENSEÑANZA MEDIA EN ESPAÑA
Authors: Del Alcázar Josep Lluís
Published: August 2016

Ensaio Acadêmico
FORMAÇÃO PEDAGÓGICA E ESTÉTICA NA DISCIPLINA DE ESTÁGIO SUPERVISIONADO: APRENDIZAGENS DOCENTES DE ESTUDANTES UNIVERSITÁRIOS
Authors: Moraes Ana Cristina , Castro Francisco Mirtiel Frankson Moura , Porto Bernadete Souza , Moura Rogério Adolfo
Published: August 2016

Este artigo reflete sobre vivências formativas na disciplina Estágio Supervisionado realizadas em duas universidades públicas estaduais do Brasil – uma localizada no Nordeste e outra no Sudeste. As análises focalizam as aprendizagens constituídas com experimentações estético-pedagógicas na referida disciplina, tomando-as como elementos essenciais à formação integral e sensível de professores. O texto fundamenta-se em estudo bibliográfico de autores como Barreiros e Gebran (2006), Buriolla (2005), Farias et. al. (2008), Fazenda (1995), Imbernon (2009), Pimenta (2011; 2008), dentre outros. Também foi desenvolvida pesquisa empírica de caráter qualitativo, envolvendo observação participante, registros em diário de campo e entrevistas. Análises revelam que a unidade teoria-prática é percebida pelos estudantes na disciplina referida, e que as vivências apresentadas articularam múltiplos saberes, como os estéticos, de práticas de ensino, pedagógicos e inter-relacionais.
O PROGRAMA ENSINO MÉDIO INOVADOR EM SANTA CATARINA E AS TECNOLOGIAS DIGITAIS
Authors: Menegaz Eliana Scremin , Lunardi Mendes Geovana Mendonça
Published: August 2016

Este artigo discute a inserção de tecnologias digitais no Programa Ensino Médio Inovador nas escolas de Santa Catarina. Esse programa foi criado para provocar o debate sobre o Ensino Médio junto aos Sistemas de Ensino Estaduais e Distrital fomentando o redesenho curricular, pautado em oito macrocampos, dentre eles, a Comunicação, Cultura Digital e Uso de Mídias. No desenvolvimento do trabalho realizou-se uma pesquisa documental utilizando, como fontes, os Projetos de Redesenho Curricular das escolas e os Documentos Orientadores do programa. Com base no material empírico, este estudo mapeia as escolas que optaram pelo macrocampo acima citado, identificando as ações desenvolvidas e o que apontam sobre a utilização das tecnologias digitais. Trata-se de um subprojeto de pesquisa vinculado ao projeto Tablets, computadores e laptops: análise sobre políticas e aspectos pedagógicos da inserção de novas tecnologias na escola, financiado com recursos do OBEDUC/CAPES.
A FORMAÇÃO DO PROFESSOR DO ENSINO MÉDIO NO BRASIL E O PLANO NACIONAL DE EDUCAÇÃO
Authors: Costa Gilvan Luiz Machado , Oliveira Claudinéia Da Silva , Medeiros Gilvan
Published: August 2016

O artigo tem como objeto a formação do professor do Ensino Médio. Objetiva-se compreender aspectos que apontem as configurações da formação inicial e continuada dos professores do Ensino Médio, alinhados a tornar a Educação Básica de fato, um direito social. Realizou-se a discussão com base em indicadores educacionais relacionados ao Nível de Escolaridade e Formação Acadêmica, com destaque ao indicador Adequação da Formação Docente, e nas metas 15 e 16 do Plano Nacional de Educação, aprovado pela Lei nº 13.005/2014. Os dados apontam os limites e as possiblidades relacionadas à formação inicial e continuada do professor do Ensino Médio no Brasil. Ao mesmo tempo em que explicitam a distância em relação ao proposto nas metas 15 e 16, expressam avanços relacionados à elevação da formação acadêmica do professor da escola média.
Penerapan Prinsip Kehati-hatian dalam Pembiayaan dan Kredit di BRI Unit Mlarak dan BMT Hasanah Ponorogo
Authors: Mujiono Agus
Published: August 2016

Abstract: Bank Indonesia, through the Bank Indonesia Regulation (PBI) No. 6/10 / PBI / 2004 dated 12 April 2004 on the System of Assessment of the Soundness of Financial Institutions, determined that the maximum tolerated NPL (non-performing loans) and NPF (non performing finance) is 5%. It was found that the average NPL at BRI Mlarak Ponorogo is only 1%, while NPF at BMT Hasanah Mlarak reached an average of 15%. The discrepancy in numbers is due to the inequality in the application of the precautionary principle, especially in the provision of financing. This study compares the application of the principles of prudence in the process of financings and loans in both institutions. It was found that: First, prudential standards in BRI Unit Mlarak are based on the guidelines for the implementation of micro business loans (PPKBM), while BMT Hasanah has not yet implemented the principles of prudence properly, because it has no strict standard operating procedures (SOP) of financing. Secondly, the principles of prudence have enhanced the reputation of BRI Mlarak and, conversely, the weakness of the application of these principles has negative impact on the BMT Hasanah.
Abstrak: Bank Indonesia melalui PBI Nomor 6/10/PBI/2004 tanggal 12 April 2004 tentang sistem penilaian tingkat kesehatan lembaga keuangan, menetapkan  bahwa rasio kredit bermasalah (Non Performing Loan, NPL maupun Non Performing Finance, NPF) adalah 5%. Dalam praktik pada BRI Unit Mlarak Kabupaten Ponorogo dengan rata-rata NPL hanya 1% sedangkan BMT Hasanah Kecamatan Mlarak rata-rata NPF 15%. Perbedaan angka NPL dan NPF diantarnya disebabkan oleh perbedaan penerapan prinsip kehati-hatian khususnya dalam pemberian pembiayaan/kredit. Penelitian ini mengkaji seputar penerapan prinsip kehati-hatian dalam proses pembiayaan dan kredit di kedua lembaga tersebut. Berdasarkan penelitian, temuan peneliti, Pertama, implementasi prinsip kehati-hatian di BRI Unit Mlarak melalui mekanisme PPKBM atau Pedoman Pelaksanaan Kredit Bisnis Mikro. Sementara pada BMT Hasanah belum melaksanakan prinsip kehati-hatian dengan benar karena belum adanya SOP pembiayaan. Kedua, Implikasi prinsip kehati-hatian di BRI Mlarak memberikan dampak positif secara bisnis dan reputasi. Sedangkan di BMT Hasanah berdampak negatif dengan NPF tinggi, karena kualitas SDM dan dukungan IT yang belum memadai sehingga perlu penerapan good corporate governance.
Urgensi Penerapan Celestial Management Bagi Sumber Daya Manusia Di Bank Syariah
Authors: Trimulato Trimulato
Published: August 2016

Abstract: Islamic banking currently has a strong legal law with the presence of the law number 21 of 2008 on banking syari'ah.Hal This adversely affects the existence of the banking Shari'ah are increasingly in demand by many. Islamic bank continues to grow and continue to open office services in various areas. Thus iru development of Islamic banks must be matched with adequate resources and qualified. Noted labor in Islamic banks continued to grow, from November 2014 to November 2015 grew to 23.51%. Not only the quantity but the quality should also be considered, it takes a celestial concept should be applied for the Management of human resources in Islamic banks. This paper uses a descriptive qualitative limitations in this paper is focused on the human resources that exist in the Islamic bank. The need for the application of celestial management for human resources in the bank syariahi. The results of this paper that the human resources in Islamic banks is growing, then the need for the application of celestial management for human resources in Islamic banks to create good quality. Because the Islamic bank is an institution whose business is inseparable from the rule of religion or spiritual aspect.

 Abstrak: Perbankan syari’ah saat ini telah memiliki payung hukum yang kuat dengan hadirnya undang-undang nomor 21 tahun 2008 tentang perbankan syari’ah.Hal ini sangat berpengaruh terhadap eksistensi dari perbankan syari’ah yang semakin diminati oleh banyak kalangan. Bank syari’ah terus berkembang dan terus membuka layanan kantor di berbagai daerah. Maka dari iru perkembangan bank syariah harus diimbangi dengan sumber daya yang mencukupi dan berkualitas. Tercatat tenaga kerja di bank syariah terus bertambah, dari November 2014 sampai November 2015 mengalami pertumbuhan hingga 23,51%. Tidak hanya dari kuantitas tapi kualitas juga harus diperhatikan, dibutuhkan sebuah konsep celestial manajement yang harus diterapkan bagi sumber daya manusia di bank syariah. Penulisan ini menggunakan jenis deskriptif kualitatif, Batasan dalam tulisan ini difokuskan pada sumber daya manusia yang ada di bank syari’ah. Perlunya penerapan celestial management bagi sumber daya manusia di bank syariahi. Hasil dari tulisan ini bahwa sumber daya manusia di bank syariah mengalami pertumbuhan,kemudian perlunya penerapan celestial management bagi sumber daya manusia di bank syariah untuk menciptakan kualitas yang baik. Karena bank syariah adalah lembaga bisnis yang tidak terlepas dari aturan agama atau aspek spiritual.

 
Penerapan Peminjaman Mandiri Berbasis SLiMS Versi Desktop: Studi Kasus di Perpustakaan STAIN Kediri
Authors: Hamim Muhamad
Published: August 2016

Abstrak; Layanan peminjaman mandiri adalah layanan peminjaman yang dilakukan sendiri oleh pemustaka. Peminjaman mandiri merupakan antarmuka peminjaman koleksi perpustakaan yang terkoneksi dengan database perpustakaan berbasis SLiMS sebagai pusat datanya. Tujuan layanan mandiri adalah untuk mengefektifkan layanan peminjaman di Perpustakaan STAIN Kediri yang memiliki petugas terbatas. Sebelumnya, transaksi peminjaman dilakukan oleh seorang petugas saja. Sering terjadi antrian panjang terutama ketika perpustakaan menjelang tutup atau istirahat. Sehingga diperlukan alternatif pelaksanaan transaksi peminjaman yang lebih efektif dan efisien. Layanan mandiri dikembangkan dengan menggunakan bahasa pemrograman lazarus freepascal dan mengambil data dari aplikasi senayan. Proses peminjaman dilakukan dengan melakukan verifikasi user akun pemustaka, verifikasi koleksi dan verifikasi peminjaman di database SLiMS.

Abstract; Selfservice loan isa loan services conducted by the member of library themselves. Self services loan is interface loan transaction that connected to SLiMS Library database server. The purpose is to get more efectivelly loan services at Library of STAIN Kediri because of the lack of staffs. Before hand, Loan services was controlled by one operator. Long waiting line happens almost everyday asspecially at the approach of closing library or break time. however, it needed to develop the loan services that is more effective and eficient. Self sevices loan is developed by using Lazarus free Pascal software and the data is connected to senayan database. Self services loan processed is initiated from the verification of user account, verification of bibliography data and verification of loan data in the SLiMS database.
Institutional Repository Sebagai Sarana Komunikasi Ilmiah Yang Sustainable Dan Reliable
Authors: Harliansyah Faizuddin
Published: August 2016

Abstract; Institutional repositories development has drawn the attention of many scholars throughout the world. Using the keywords ‘institutional repositories’, there are over 300 peer-reviewed articles related on the topic has been indexed in Library, Information Science, & Technology Abstracts (LISTA) and SCOPUS. There are also hundreds of theses, dissertations, and websites dedicated on this blooming trends. These are proofs that the importance of IR in higher education has been acknowledged by many professionals in the field. This paper aims at clarifying the role of repositories in strengthening scholarly communication in higher education and research institution and explaining some basic repositories concepts (types of repositories and their characteristics), as well as exploring its relations with open access movement, the development ideas, and resources that could be kept in repositories and deposit policies.

Abstrak; Pengembangan institutional repositories telah banyak menyita perhatian dari kalangan ilmiah di seluruh dunia. Melalui kata kunci ‘institutional repositories’, ada lebih dari 300 artikel terulas mitra bestari yang berhubungan dengan topik ini, yang telah terindeks di Library, Information Science, & Technology Abstracts (LISTA), dan SCOPUS. Terdapat juga ratusan tesis, disertasi, dan website yang mengulas trend ini. Inilah bukti bahwa pentingnya institutional repositories (IR) telah dipahami oleh para profesional di bidangnya. Tulisan ini akan menjelaskan aturan-aturan repository dalam memperkuat komunikasi ilmiah di perguruan tinggi dan lembaga riset, menjelaskan konsep-konsep dasar repositories, termasuk tipe-tipe repository dan karakteristiknya. Tulisan ini juga akan memperdalam konsep repositories dalam hubungannya dengan gerakan open access, pengembangan ide-ide, sumber-sumber ilmiah yang dapat disimpan di repositories, serta kebijakan penyimpanan di dalamnya.

 
A Next-Generation Shock-Capturing, Multi-Phase Flow Simulator for Perforating Applications in HPHT Environment
Authors: Bale D. S. , Satti R. P. , Ji M.. , Howard J. J.
Published: August 2016

As the Oil and Gas industry looks forward to perforating next-generation complex wells (including but not limited to HPHT, deepwater, geothermal, multi-stage long horizontals etc.), computational modeling tools have been increasingly used to predict the transient flow physics that govern the design and optimization of perforating jobs. In particular, it is crucial to accurately predict the unsteady wellbore flow dynamics and relevant shock physics that typically occur during perforation jobs. Such modeling capabilities provide us the ability to prevent downhole equipment failures that may result from shock loading as well as lead to accurate predictions of perforation cleanup process which depends on balance of pressures in the reservoir, wellbore and gun. In addition, as complex completions such as those found in subsea wells and long horizontal wells are becoming more important, so is the need to extend such a predictive capability to higher-pressure and higher-temperature environment that often accompanies such wells.

To address the above, this study is focused on the development and verification of a next-generation transient wellbore flow simulator that is used in conjunction with our existing perforation modeling software. The use of appropriate numerical algorithms allows the simulator to accurately capture unsteady compressible wellbore flows with large gradients of flow quantities. The set of governing equations for compressible flows are closed with improved thermodynamic equations of state, specifically designed to model extreme high pressure (up to 40,000 psi) and temperatures (up to 600 °F).

Computational results from various shock-tube test cases show good agreement among exact solutions, single-phase numerical solutions, and the new three-phase solutions. Compared with our existing perforation modeling software, the next-generation simulator exhibits improved accuracy for HPHT environment, better shock-capturing properties, and improved computational efficiency. This unique computational tool has been integrated into an existing perforation job-design workflow to realize significant improvements in risk mitigation and design parameter optimization. This improved workflow enables a new decision process to better model and design challenging deepwater/HPHT perforating applications.
A Novel Inflow Control Device Design Philosophy of Optimizing Horizontal Well Performance
Authors: Cao Mengjing , Wu Xiaodong , An Yongsheng , Han Guoqing , Wang Ruihe , Liang Bin
Published: August 2016

Horizontal wells in bottom-water reservoir equipped with inflow control devices (ICDs) are a proven technology of delaying influx of water to help maximize oil production by creating additional pressure drop, adjusting horizontal wellbore pressure distribution, and thus, achieving an even influx profile. Owing to completion risk and investment venture, especially offshore field, it’s essential to design ICDs (number, location, type, size, etc.) effectively in order to improve production and net present value (NPV), otherwise the ICDs even would be overlooked. Conventional ICDs design is aiming to attain equal influx along the horizontal wellbore, which would delay water production, as well as oil potential production, unfortunately. This paper will use reservoir simulation to study four production strategies and analyze the benefits of delaying water and improving oil production. The four strategies considered are (i) no ICD, (ii) stinger water-control completion, (iii) ICD (conventional design), (iv) ICD (design based on the principle of maximizing oil production). The simulation results and analysis will show the disadvantage of conventional ICDs design method. This paper will develop a novel ICD design philosophy on the basis of maximizing oil production before water breakthrough. In this paper, we will evaluate an offshore field case, which suffers from water coning, to compare the novel design philosophy with conventional one. The actual role of conventional ICDs design in delaying water coning will be found in this paper to sacrifice oil production reduction, which has negative impact on horizontal well performance and eventually results in ultimate oil recovery decrease. Instead, ICDs based on the novel ICD design philosophy presented in this paper will be proven to be more effective to improve oil production, while water coning from bottom-water reservoir can be delayed.