bluuebunny/crossref_metadata_2025 huggingface dataset:
Fontan Conversion
Authors: Mavroudis Constantine , Deal Barbara J.
Published: March 2016

Early survival after the Fontan operation has improved significantly leading to a lifetime of Fontan circulation for patients. There is a natural progression of pulmonary artery pressure during the human lifetime that is easily tolerated in two-ventricle physiology but is deleterious for single-ventricle physiology. Obstructions in the venous to pulmonary artery pathway and pulmonary venous return or ventricular outflow, atrioventricular valve dysfunction (regurgitation), pulmonary arteriovenous malformations, venous thrombosis, and the development of atrial arrhythmias can lead to reduced functional status. These complications have been demonstrated in older patients with largely atriopulmonary connections owing to time accrual and unfavorable flow characteristics. Various surgical and catheter interventions aimed at reducing morbidity and mortality have been attempted to treat these identifiable abnormalities. The purpose of this article is to review the extant literature on Fontan Conversion and to assess the lessons learned over 20 years.
“Just-In-Time” Simulation Training Using 3-D Printed Cardiac Models After Congenital Cardiac Surgery
Authors: Olivieri Laura J. , Su Lillian , Hynes Conor F. , Krieger Axel , Alfares Fahad A. , Ramakrishnan Karthik , Zurakowski David , Marshall M. Blair , Kim Peter C. W. , Jonas Richard A. , Nath Dilip S.
Published: March 2016

Background:

High-fidelity simulation using patient-specific three-dimensional (3D) models may be effective in facilitating pediatric cardiac intensive care unit (PCICU) provider training for clinical management of congenital cardiac surgery patients.

Methods:

The 3D-printed heart models were rendered from preoperative cross-sectional cardiac imaging for 10 patients undergoing congenital cardiac surgery. Immediately following surgical repair, a congenital cardiac surgeon and an intensive care physician conducted a simulation training session regarding postoperative care utilizing the patient-specific 3D model for the PCICU team. After the simulation, Likert-type 0 to 10 scale questionnaire assessed participant perception of impact of the training session.

Results:

Seventy clinicians participated in training sessions, including 22 physicians, 38 nurses, and 10 ancillary care providers. Average response to whether 3D models were more helpful than standard hand off was 8.4 of 10. Questions regarding enhancement of understanding and clinical ability received average responses of 9.0 or greater, and 90% of participants scored 8 of 10 or higher. Nurses scored significantly higher than other clinicians on self-reported familiarity with the surgery (7.1 vs 5.8; P = .04), clinical management ability (8.6 vs 7.7; P = .02), and ability enhancement (9.5 vs 8.7; P = .02). Compared to physicians, nurses and ancillary providers were more likely to consider 3D models more helpful than standard hand off (8.7 vs 7.7; P = .05). Higher case complexity predicted greater enhancement of understanding of surgery ( P = .04).

Conclusion:

The 3D heart models can be used to enhance congenital cardiac critical care via simulation training of multidisciplinary intensive care teams. Benefit may be dependent on provider type and case complexity.
Some Determinants of Trust Formation and Pro-social Behaviours in Investment Games: An Experimental Study
Authors: Bartolomeo Giovanni Di , Papa Stefano
Published: March 2016

This study aims to examine some ‘circumstances’ that may influence trust formation and, in general, pro-social behaviours in game situations characterized by complex strategies, that is, not dichotomous choices. We consider the potential role played by one-way communication (cheap talk), social history, and ‘climate effects’ induced by meditation in a single experiment based on the investment game. Our main findings are that meditation enhances trust formation, while social history and cheap talk have limited or no effect on it—at least on average.
Employment Status and Health in Spain Before and After the Great Recession
Authors: Sánchez-Moreno Esteban , Gallardo-Peralta Lorena P. , Barrón Ana , Arias-Astray Andrés , de la Fuente-Roldán Iria-Noa
Published: March 2016

This article analyzes the relationship between employment status (ES), on one hand, and self-rated health and psychological distress, on the other, in the context of the Great Recession beginning in 2008. For this purpose, it is necessary to move beyond the employment/unemployment dichotomy characteristics of previous theories and research concerning the relationship between the labor market, recession, and health. The authors use data from the Spanish National Health Surveys in 2006 ( n = 15,128), before the crisis, and in 2012 ( n = 11,124), when its consequences had taken effect. The results of the regression analysis indicate a structural change in the relationship between ES and health. Health inequality patterns changed during the crisis, with increased deterioration in the health of unemployed, especially the long-term unemployed, and self-employed workers. Health inequalities were reduced for temporary workers. The results support the idea that the structure of the association between ES and health varies according to the economic cycle. The association between recession, ES, and health would be directly related to the specific characteristics of the economic and employment contexts under study. In the Spanish case, labor market segmentation processes based on numerical flexibility—a key feature of the Mediterranean Variety of Capitalism—may explain the results obtained.
A Classroom Experience That Builds the Top Skills Employers Want
Authors: Smith Kirk
Published: March 2016

National surveys routinely list the skills employers look for in new college graduates. This article describes a classroom activity that helps build those skills in your students but does not require dedicating your whole course to the effort. Guests from the business world visit class for only 1 hour and bring real problems for the students to work on while the client visits. Students must quickly analyze the client’s situation, develop possible solutions in a team and time-pressured environment, and then present their ideas to the guest within that hour. Nine iterations during the semester seems to be enough.
Climate Change, Food Security, and Water Management in South Asia: Implications for Regional Cooperation
Authors: Kaur Simrit , Kaur Harpreet
Published: March 2016

Global warming, climate change and greenhouse gas emissions have been the context of several deliberations since the 1992 Rio Earth Summit. Climate change is a critical issue, especially for the developing economies of South Asia. The region’s geographical dynamics, accompanied by the presence of substantial poverty, undernourished people, and food insecure population, adds to its vulnerability to climate change through a number of ways including their livelihoods, food availability, and affordability. The rivers of the region are the lifelines of the economy providing water to more than half of the world’s population. The increased occurrence of temperature extremes, altered rainfall patterns, rise in frequency of deficit monsoons, and heavy precipitation events observed in the region are the outcomes of climate change. Regretfully, these trends are projected to continue challenging the growth and development in the region, thereby necessitating cooperation among member countries. In this context, an analysis of the food and water security situation is undertaken, along with the expected impacts of climate change on the same. The article concludes by recommending policies that address public investments in agriculture, regional food stocks, and cooperation on water issues.
Ranking reactive glutamines in the fibrinogen αC region that are targeted by blood coagulant factor XIII
Authors: Mouapi Kelly Njine , Bell Jacob D. , Smith Kerrie A. , Ariëns Robert A. S. , Philippou Helen , Maurer Muriel C.
Published: March 2016

Key Points

FXIIIa exhibits a preference for Q237 in crosslinking reactions within fibrinogen αC (233-425) followed by Q328 and Q366. None of the reactive glutamines in αC 233-425 (Q237, Q328, and Q366) are required to react first before the others can crosslink.
Blunted perception of neural respiratory drive and breathlessness in patients with cystic fibrosis
Authors: Reilly Charles C. , Jolley Caroline J. , Elston Caroline , Moxham John , Rafferty Gerrard F.
Published: March 2016

The electromyogram recorded from the diaphragm (EMGdi) and parasternal intercostal muscle using surface electrodes (sEMGpara) provides a measure of neural respiratory drive (NRD), the magnitude of which reflects lung disease severity in stable cystic fibrosis. The aim of this study was to explore perception of NRD and breathlessness in both healthy individuals and patients with cystic fibrosis. Given chronic respiratory loading and increased NRD in cystic fibrosis, often in the absence of breathlessness at rest, we hypothesised that patients with cystic fibrosis would be able to tolerate higher levels of NRD for a given level of breathlessness compared to healthy individuals during exercise.

15 cystic fibrosis patients (mean forced expiratory volume in 1 s (FEV1) 53.5% predicted) and 15 age-matched, healthy controls were studied. Spirometry was measured in all subjects and lung volumes measured in the cystic fibrosis patients. EMGdiand sEMGparawere recorded at rest and during incremental cycle exercise to exhaustion and expressed as a percentage of maximum (% max) obtained from maximum respiratory manoeuvres. Borg breathlessness scores were recorded at rest and during each minute of exercise.

EMGdi% max and sEMGpara% max and associated Borg breathlessness scores differed significantly between healthy subjects and cystic fibrosis patients at rest and during exercise. The relationship between EMGdi% max and sEMGpara% max and Borg score was shifted to the right in the cystic fibrosis patients, such that at comparable levels of EMGdi% max and sEMGpara% max the cystic fibrosis patients reported significantly lower Borg breathlessness scores compared to the healthy individuals. At Borg score 1 (clinically significant increase in breathlessness from baseline) corresponding levels of EMGdi% max (20.2±12%versus32.15±15%, p=0.02) and sEMGpara% max (18.9±8%versus29.2±15%, p=0.04) were lower in the healthy individuals compared to the cystic fibrosis patients.

In the cystic fibrosis patients EMGdi% max at Borg score 1 was related to the degree of airways obstruction (FEV1) (r=−0.664, p=0.007) and hyperinflation (residual volume/total lung capacity) (r=0.710, p=0.03). This relationship was not observed for sEMGpara% max.

These data suggest that compared to healthy individuals, patients with cystic fibrosis can tolerate much higher levels of NRD before increases in breathlessness from baseline become clinically significant. EMGdi% max and sEMGpara% max provide physiological tools with which to elucidate factors underlying inter-individual differences in breathlessness perception.
Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL)
Authors: Koestler Devin C. , Jones Meaghan J. , Usset Joseph , Christensen Brock C. , Butler Rondi A. , Kobor Michael S. , Wiencke John K. , Kelsey Karl T.
Published: March 2016

Background

Confounding due to cellular heterogeneity represents one of the foremost challenges currently facing Epigenome-Wide Association Studies (EWAS). Statistical methods leveraging the tissue-specificity of DNA methylation for deconvoluting the cellular mixture of heterogenous biospecimens offer a promising solution, however the performance of such methods depends entirely on the library of methylation markers being used for deconvolution. Here, we introduce a novel algorithm for Identifying Optimal Libraries (IDOL) that dynamically scans a candidate set of cell-specific methylation markers to find libraries that optimize the accuracy of cell fraction estimates obtained from cell mixture deconvolution.

Results

Application of IDOL to training set consisting of samples with both whole-blood DNA methylation data (Illumina HumanMethylation450 BeadArray (HM450)) and flow cytometry measurements of cell composition revealed an optimized library comprised of 300 CpG sites. When compared existing libraries, the library identified by IDOL demonstrated significantly better overall discrimination of the entire immune cell landscape (p = 0.038), and resulted in improved discrimination of 14 out of the 15 pairs of leukocyte subtypes. Estimates of cell composition across the samples in the training set using the IDOL library were highly correlated with their respective flow cytometry measurements, with all cell-specific R2>0.99 and root mean square errors (RMSEs) ranging from [0.97 % to 1.33 %] across leukocyte subtypes. Independent validation of the optimized IDOL library using two additional HM450 data sets showed similarly strong prediction performance, with all cell-specific R2>0.90 and RMSE<4.00 %. In simulation studies, adjustments for cell composition using the IDOL library resulted in uniformly lower false positive rates compared to competing libraries, while also demonstrating an improved capacity to explain epigenome-wide variation in DNA methylation within two large publicly available HM450 data sets.

Conclusions

Despite consisting of half as many CpGs compared to existing libraries for whole blood mixture deconvolution, the optimized IDOL library identified herein resulted in outstanding prediction performance across all considered data sets and demonstrated potential to improve the operating characteristics of EWAS involving adjustments for cell distribution. In addition to providing the EWAS community with an optimized library for whole blood mixture deconvolution, our work establishes a systematic and generalizable framework for the assembly of libraries that improve the accuracy of cell mixture deconvolution.
CoeViz: a web-based tool for coevolution analysis of protein residues
Authors: Baker Frazier N. , Porollo Aleksey
Published: March 2016

Background

Proteins generally perform their function in a folded state. Residues forming an active site, whether it is a catalytic center or interaction interface, are frequently distant in a protein sequence. Hence, traditional sequence-based prediction methods focusing on a single residue (or a short window of residues) at a time may have difficulties in identifying and clustering the residues constituting a functional site, especially when a protein has multiple functions. Evolutionary information encoded in multiple sequence alignments is known to greatly improve sequence-based predictions. Identification of coevolving residues further advances the protein structure and function annotation by revealing cooperative pairs and higher order groupings of residues.

Results

We present a new web-based tool (CoeViz) that provides a versatile analysis and visualization of pairwise coevolution of amino acid residues. The tool computes three covariance metrics: mutual information, chi-square statistic, Pearson correlation, and one conservation metric: joint Shannon entropy. Implemented adjustments of covariance scores include phylogeny correction, corrections for sequence dissimilarity and alignment gaps, and the average product correction. Visualization of residue relationships is enhanced by hierarchical cluster trees, heat maps, circular diagrams, and the residue highlighting in protein sequence and 3D structure. Unlike other existing tools, CoeViz is not limited to analyzing conserved domains or protein families and can process long, unstructured and multi-domain proteins thousands of residues long. Two examples are provided to illustrate the use of the tool for identification of residues (1) involved in enzymatic function, (2) forming short linear functional motifs, and (3) constituting a structural domain.

Conclusions

CoeViz represents a practical resource for a quick sequence-based protein annotation for molecular biologists, e.g., for identifying putative functional clusters of residues and structural domains. CoeViz also can serve computational biologists as a resource of coevolution matrices, e.g., for developing machine learning-based prediction models. The presented tool is integrated in the POLYVIEW-2D server (http://polyview.cchmc.org/) and available from resulting pages of POLYVIEW-2D.
Endothelial permeability following coronary artery bypass grafting: an observational study on the possible role of angiopoietin imbalance
Authors: Hilbert Tobias , Duerr Georg Daniel , Hamiko Marwan , Frede Stilla , Rogers Lynette , Baumgarten Georg , Hoeft Andreas , Velten Markus
Published: March 2016

Background

Unresolved inflammation resulting in capillary leakage with endothelial barrier dysfunction is a major contributor to postoperative morbidity and mortality after coronary artery bypass graft (CABG). Angiopoietins (ANGs) are vascular growth factors, also mediating inflammation and disruption of the endothelium, thus inducing capillary leakage. We hypothesized that changes in the relative serum levels of ANG1 and ANG2 influence endothelial barrier function and perioperative morbidity after CABG.

Methods

After approval and informed consent, serum samples (n = 28) were collected pre CABG surgery, 1, 6, and 24 h after aortic de-clamping. ANG1, ANG2, soluble ANG receptor TIE2 (sTIE2), and IL-6 serum concentrations were analyzed by ELISA. Human pulmonary microvascular endothelial cells (HPMECs) were incubated with patient serum and FITC-dextran permeability was assessed. Furthermore, ANG2 secretion of HPMECs was analyzed after incubation with IL-6-containing patient serum.

Results

CABG induced an early and sustained increase of ANG2/ANG1 ratio (5-fold after 24 h compared to pre-surgery). These changes correlated with elevated serum lactate levels, fluid balance, as well as the duration of mechanical ventilation. Permeability of HPMECs significantly increased after incubation with post-surgery serum showing a marked shift of ANG2/ANG1 balance (18-fold) compared to serum with a less pronounced increase (6-fold). Furthermore, CABG resulted in increased IL-6 serum content. Pre-incubation with serum containing high levels of IL-6 amplified the ANG2 secretion by HPMECs; however, this was not influenced by blocking IL-6.

Conclusions

CABG affects the balance between ANG1 and ANG2 towards a dominance of the barrier-disruptive ANG2. Our data suggest that this ANG2/ANG1 imbalance contributes to an increased postoperative endothelial permeability, likewise being reflected by the clinical course. The results strongly suggest a biological effect of altered angiopoietin balance during cardiac surgery on endothelial permeability.
A new look at technical progress and early retirement
Authors: Burlon Lorenzo , Vilalta-Bufí Montserrat
Published: March 2016

Technical progress affects early retirement in two opposing ways. On the one hand, it increases real wages and thus produces an incentive to postpone retirement. On the other hand, it erodes workers’ skills, making early retirement more likely. We re-examine the effect of technical progress on early retirement in the US. We measure technical change during the whole working life of the individuals and find that its effect on the probability of early retirement is non-monotonic. In particular, when technical change is small, the erosion effect dominates, but when it is large the wage effect dominates. These results may signal that the higher the technical change, the more willing are the elderly to retrain, which has direct policy implications for the design of elderly training programs.

Jel codes:J24, J26, O33
Do state work eligibility verification laws reduce unauthorized immigration?
Authors: Orrenius Pia M. , Zavodny Madeline
Published: March 2016

During the 2000s, several states adopted laws requiring employers to verify new employees’ eligibility to work legally in the USA. This study uses data from the 2005–2014 American Community Survey to examine how such laws affect unauthorized immigrants’ locational choices. The results indicate that having an E-Verify law reduces the number of less-educated prime-age immigrants from Mexico and Central America—immigrants who are likely to be unauthorized—living in a state. We find evidence that some new migrants are diverted to other states, but also suggestive evidence that some already-present migrants leave the country entirely.

JEL codes: J15, J61, J68
Patient-Reported Outcomes After Choice for Contralateral Prophylactic Mastectomy
Authors: Hwang E. Shelley , Locklear Tracie D. , Rushing Christel N. , Samsa Greg , Abernethy Amy P. , Hyslop Terry , Atisha Dunya M.
Published: March 2016

Purpose

The rate of contralateral prophylactic mastectomies (CPMs) continues to rise, although there is little evidence to support improvement in quality of life (QOL) with CPM. We sought to ascertain whether patient-reported outcomes and, more specifically, QOL differed according to receipt of CPM.

Methods

Volunteers recruited from the Army of Women with a history of breast cancer surgery took an electronically administered survey, which included the BREAST-Q, a well-validated breast surgery outcomes patient-reporting tool, and demographic and treatment-related questions. Descriptive statistics, hypothesis testing, and regression analysis were used to evaluate the association of CPM with four BREAST-Q QOL domains.

Results

A total of 7,619 women completed questionnaires; of those eligible, 3,977 had a mastectomy and 1,598 reported receipt of CPM. Women undergoing CPM were younger than those who did not choose CPM. On unadjusted analysis, mean breast satisfaction was higher in the CPM group (60.4 v 57.9, P < .001) and mean physical well-being was lower in the CPM group (74.6 v 76.6, P < .001). On multivariable analysis, the CPM group continued to report higher breast satisfaction (P = .046) and psychosocial well-being (P = .017), but no difference was reported in the no-CPM group in the other QOL domains.

Conclusion

Choice for CPM was associated with an improvement in breast satisfaction and psychosocial well-being. However, the magnitude of the effect may be too small to be clinically meaningful. Such patient-reported outcomes data are important to consider when counseling women contemplating CPM as part of their breast cancer treatment.
Cardiovascular Disease Risk Profiles in Survivors of Adolescent and Young Adult (AYA) Cancer: The Kaiser Permanente AYA Cancer Survivors Study
Authors: Chao Chun , Xu Lanfang , Bhatia Smita , Cooper Robert , Brar Somjot , Wong F. Lennie , Armenian Saro H.
Published: March 2016

Purpose

To describe the epidemiology and risk factors for cardiovascular disease (CVD) in survivors of adolescent and young adult (AYA) cancer.

Methods

We identified a retrospective cohort of 2-year survivors of AYA cancer who were diagnosed between the ages of 15 to 39 years (1998 to 2009) at Kaiser Permanente Southern California. A comparison group without cancer was selected and matched 10:1 to cancer survivors on the basis of age, sex, Kaiser Permanente Southern California membership, and calendar year. Patients were followed through December 31, 2012, for coronary artery disease, heart failure, and stroke. Time-dependent Poisson regression was used to evaluate the effect that cancer survivorship had on the risk of developing CVD, adjusted for cardiovascular risk factors (CVRFs; ie, diabetes, hypertension, and dyslipidemia), ethnicity, smoking, and overweight/obesity. Among cancer survivors, mortality risk by CVD status was examined using Cox regression.

Results

A total of 5,673 2-year survivors of AYA cancer and 57,617 comparison patients were included, representing 24,839 and 239,073 person-years of follow-up, respectively. Overall, cancer survivors had more than two-fold risk of developing CVD (adjusted incidence rate ratio, 2.37; 95% CI, 1.93 to 2.93) when compared with patients without cancer; survivors of leukemia and breast cancer were at the highest risk (adjusted incidence rate ratio, 4.23; 95% CI, 1.73 to 10.31; and 3.63; 95% CI, 2.41 to 5.47, respectively) of developing CVD. Having any of the CVRFs increased the risk of CVD in cancer survivors. Cancer survivors who developed CVD had an 11-fold increased overall mortality risk (hazard ratio, 10.9; 95% CI, 8.1 to 14.8) when compared with survivors without CVD.

Conclusion

Survivors of AYA cancer are at increased risk for developing CVD. Survival after CVD onset is compromised, and CVRFs are independent modifiers of CVD risk. These data form the basis for identifying high-risk individuals and proactive management of CVRFs.
A direct role for murine Cdx proteins in the trunk neural crest-gene regulatory network
Authors: Sanchez-Ferras Oraly , Bernas Guillaume , Farnos Omar , Touré Aboubacrine M. , Souchkova Ouliana , Pilon Nicolas
Published: March 2016

Numerous studies in chordates and arthropods currently indicate that Cdx proteins have a major ancestral role in the organization of post-head tissues. In urochordate embryos, Cdx loss-of-function has notably been shown to impair axial elongation, neural tube (NT) closure and pigment cell development. Intriguingly, in contrast to axial elongation and NT closure, a Cdx role in neural crest (NC)-derived melanocyte/pigment cell development has not been reported in any other chordate species. To address this, we generated a new conditional pan-Cdx functional knockdown mouse model that allows circumventing Cdx functional redundancy as well as the early embryonic lethality of Cdx mutants. Through directed inhibition in the neuroectoderm, we here provide in vivo evidence that murine Cdx proteins impact melanocyte and enteric nervous system development via, at least in part, directly controlling the expression of the key early regulators of NC ontogenesis Pax3, Msx1 and FoxD3. Our work thus reveals a novel role for the Cdx proteins atop of the trunk NC-gene regulatory network in the mouse, which appears to be inherited from their ancestral orthologue.
ΟΙ ΙΚΕΤΑΙ ΠΑΡΑ ΤΟΙΣ ΑΡΧΑΙΟΙΣ ΕΛΛΗΣΙ
Authors: PAMΟY — ΧΑΨΙΑΔΗ ANNA
Published: March 2016

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Η ΙΔΡΥΣΗ ΤΟΥ ΕΛΛΗΝΙΚΟΥ ΠΡΟΞΕΝΕΙΟΥ ΤΗΣ ΜΑΛΤΑΣ (1827)
Authors: ΓΑΡΔΙΚΑ ΕΛΕΝΗ
Published: March 2016

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ΤΑ ΤΣΙΦΛΙΚΙΑ ΤΟΥ ΒΕΛΗ ΠΑΣΑ ΥΙΟΥ ΤΟΥ ΑΛΗ ΠΑΣΑ
Authors: ΓΙΑΝΝΟΠΟΥΛΟΣ ΙΩΑΝΝΗΣ Γ
Published: March 2016

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ΜΕΤΑΣΧΗΜΑΤΙΣΤΙΚΗ ΑΝΑΛΥΣΙΣ ΤΩΝ ΣΥΜΠΛΗΡΩΜΑΤΙΚΩΝ ΠΡΟΤΑΣΕΩΝ ΤΗΣ ΝΕΑΣ ΕΛΛΗΝΙΚΗΣ ΓΛΩΣΣΗΣ
Authors: ΣΑΚΕΛΛΑΡΙΑΔΗΣ ΓΕΩΡΓΙΟΣ XP.
Published: March 2016

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Η ΠΕΡΙΟΔΕΙΑ ΤΟΥ ΑΝΔΡΕΑ ΜΕΤΑΞΑ ΣΤΗΝ ΠΕΛΟΠΟΝΝΗΣΟ (1830)
Authors: ΛΟΥΚΟΣ ΧΡΗΣΤΟΣ Κ.
Published: March 2016

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ΤΟΠΩΝΥΜΙΚΑΙ ΔΙΑΣΑΦΗΣΕΙΣ Ι. ΜΥΟΝΝΗΣΟΣ
Authors: ΠΡΟΜΠΟΝΑΣ ΙΩΑΝΝΗΣ Κ.
Published: March 2016

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Ο ΣΠ. ΤΡΙΚΟΥΠΗΣ ΕΙΣΗΓΕΙΤΑΙ ΣΤΟΝ ΟΘΩΝΑ ΤΗΝ ΠΑΡΑΧΩΡΗΣΗ ΣΥΝΤΑΓΜΑΤΟΣ (ΑΝΕΚΔΟΤΟ ΥΠΟΜΝΗΜΑ ΤΟΥ 1835)
Authors: ΛΑΜΠΙΡΗ ΑΝΤΖΕΛΑ
Published: March 2016

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Η ΔΙΚΗ ΤΟΥ ΘΕΟΚΛΗΤΟΥ ΦΑΡΜΑΚΙΔΗ (1829-1830)
Authors: ΒΑΡΘΟΛΟΜΑΙΟΥ ΒΓΕΝΑ Α.
Published: March 2016

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ΠΡΟΣΠΑΘΕΙΕΣ ΚΑΙ ΣΧΕΔΙΑ ΤΟΥ ΦΟΡΙΕΛ ΓΙΑ ΜΙΑ ΔΕΥΤΕΡΗ ΕΚΔΟΣΗ ΤΗΣ ΣΥΛΛΟΓΗΣ ΤΩΝ ΕΛΛΗΝΙΚΩΝ ΔΗΜΟΤΙΚΩΝ ΤΡΑΓΟΥΔΙΩΝ
Authors: ΠΟΛΙΤΗΣ ΑΛΕΞΗΣ
Published: March 2016

Δεν παρατίθεται περίληψη.
JUAN, JOSÉ ELIODORO BOULIGNY KAI LORENZO MABILI DE BOULIGNY : ΟΙ ΠΡΟΓΟΝΟΙ ΤΟΥ ΜΑΒΙΛΗ ΚΑΙ Η ΔΙΠΛΩΜΑΤΙΚΗ ΤΟΥΣ ΑΛΛΗΛΟΓΡΑΦΙΑ. (ΤΕΛΗ ΙΗ' - ΑΡΧΕΣ ΙΘ' ΑΙΩΝΑ)
Authors: ΧΑΣΙΩΤΗΣ Ι. Κ.
Published: March 2016

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ΑΝΤΙΠΟΙΝΑ ΤΩΝ ΓΕΡΜΑΝΙΚΩΝ ΔΥΝΑΜΕΩΝ ΚΑΤΟΧΗΣ ΣΤΗΝ ΕΛΛΑΔΑ 1941 - 1944
Authors: FLEISCHER HAGEN
Published: March 2016

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ΦΟΡΟΛΟΓΙΑ ΚΑΙ ΕΚΧΡΗΜΑΤΙΣΜΟΣ ΣΤΗΝ ΟΙΚΟΝΟΜΙΑ ΤΩΝ ΒΑΛΚΑΝΙΚΩΝ ΧΩΡΙΩΝ (15ος- 16ος αι.)
Authors: ΑΣΔΡΑΧΑΣ ΣΠΥΡΟΣ Ι.
Published: March 2016

Δεν παρατίθεται περίληψη.
ΠΟΛΙΤΕΥΟΜΕΝΟΙ ΣΤΡΑΤΙΩΤΙΚΟΙ ΣΤΗΝ ΕΛΛΑΔΑ ΣΤΑ ΤΕΛΗ ΤΟΥ 19ου ΑΙΩΝΑ
Authors: ΒΑΡΔΑ ΧΡΙΣΤΙΝΑ
Published: March 2016

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ΤΟ ΚΑΠΟΔΙΣΤΡΙΑΚΟ ΚΟΜΜΑ 1832 - 1833. ΑΠΟ ΤΗΝ ΗΤΤΑ ΣΤΟΝ ΠΑΡΑΓΚΩΝΙΣΜΟ ΚΑΙ ΤΗΝ ΚΑΤΑΔΙΩΞΗ
Authors: ΜΠΟΥΤΖΟΥΒΗ - ΜΠΑΝΙΑ ΑΛΕΚΑ
Published: March 2016

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ΤΟ ΜΟΝΟΦΥΛΛΟ ΤΟΥ ΡΗΓΑ ΤΟΥ 1797. ΠΑΡΑΤΗΡΗΣΕΙΣ ΣΤΗ ΝΕΟΕΛΛΗΝΙΚΗ ΕΙΚΟΝΟΓΡΑΦΙΑ ΤΟΥ ΜΕΓΑΛΟΥ ΑΛΕΞΑΝΔΡΟΥ
Authors: ΓΚΡΑΤΖΙΟΥ ΟΛΓΑ
Published: March 2016

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ΝΕΑ ΣΤΟΙΧΕΙΑ ΓΙΑ ΤΗ ΣΧΕΣΗ ΓΕΡΜΑΝΙΚΩΝ ΑΡΧΩΝ ΚΑΤΟΧΗΣ ΚΑΙ ΤΑΓΜΑΤΩΝ ΑΣΦΑΛΕΙΑΣ
Authors: FLEISCHER HAGEN
Published: March 2016

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Η ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΙΚΗ ΣΥΝΕΡΓΑΣΙΑ ΤΟΥ ΒΕΝΕΤΙΚΟΥ ΟΙΚΟΥ ΤΑΡΩΝΙΤΗ - ΘΕΟΤΟΚΗ ΚΑΙ ΤΩΝ ΑΔΕΛΦΩΝ Γ. ΚΑΙ Θ. ΓΕΩΡΓΙΒΑΛΩΝ (1732 -1737). (Ο ΡΟΛΟΣ ΚΑΙ Η ΔΡΑΣΗ ΤΟΥ ΕΜΠΟΡΙΚΟΥ ΠΡΑΚΤΟΡΑ ΔΗΜ. ΧΑΜΟΔΡΑΚΑ)
Authors: ΜΙΧΑΗΛΑΡΗΣ ΠΑΝΑΓΙΩΤΗΣ
Published: March 2016

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Η ΕΝΟΙΚΙΑΣΗ ΠΡΟΣΟΔΩΝ ΚΑΤΑ ΤΗΝ ΚΑΠΟΔΙΣΤΡΙΑΚΗ ΠΕΡΙΟΔΟ. ΑΠΟΨΕΙΣ ΓΙΑ ΤΗΝ ΠΟΛΙΤΙΚΗ ΔΙΑΣΤΑΣΗ ΤΟΥ ΖΗΤΗΜΑΤΟΣ
Authors: ΛΟΥΚΟΣ Χ. Κ.
Published: March 2016

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ΜΝΗΜΟΣΥΝΟ ΛΙΝΟΥ ΠΟΛΙΤΗ (1906-1982)
Authors: ΣΚΛΑΒΕΝΙΤΗΣ ΤΡΙΑΝΤΑΦΥΛΛΟΣ Ε.
Published: March 2016

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ΕΝΑ ΧΕΙΡΟΓΡΑΦΟ ΑΠΟ ΤΟ ΜΕΛΕΝΙΚΟ ΣΤΗ ΒΙΒΛΙΟΘΗΚΗ JOHN RYLANDS ΤΟΥ ΜΑΝΤΣΕΣΤΕΡ. (Ψευδο-Δωρόθεος, Λέων ΣΤ' ο Σοφός)
Authors: ΜΑΡΚΟΠΟΥΛΟΣ Α.
Published: March 2016

Δεν παρατίθεται περίληψη.
Case Report: Rectal perforation during CT colonography
Authors: Zukiwskyj Marianna , Arafat Yasser
Published: March 2016

Introduction

Computer tomography colonoscopy (CTC) is an increasingly prevalent procedure for the investigation of colorectal symptoms, or as a component of colorectal cancer screening.  It is considered a low risk procedure, however colonic perforation is a recognized significant complication.

Case Report

We report the case of an 81-year-old female patient who underwent CTC after failed optical colonoscopy as part of routine colorectal cancer screening.  Perforation of the rectum with surrounding pararectal air was confirmed on CTC.  The patient had minimal symptoms and was treated successful non-operatively with bowel rest and antibiotics.

Conclusion

Perforation sustained during CTC is an uncommon complication.  The incidence of perforation during CTC is still lower than that during optical colonoscopy.  In the absence of significant abdominal signs and symptoms, this rare complication may be successfully managed non-operatively.
How Do Delay Announcements Shape Customer Behavior? An Empirical Study
Authors: Yu Qiuping , Allon Gad , Bassamboo Achal
Published: March 2016

In this paper, we explore the impact of delay announcements using an empirical approach by analyzing the data from a medium-sized call center. We first explore the question of whether delay announcements impact customers’ behavior using a nonparametric approach. The answer to this question appears to be ambiguous. We thus turn to investigate the fundamental mechanism by which delay announcements impact customer behavior, by constructing a dynamic structural model. In contrast to the implicit assumption made in the literature that announcements do not directly impact customers’ waiting costs, our key insights show that delay announcements not only impact customers’ beliefs about the system but also directly impact customers’ waiting costs. In particular, customers’ per-unit waiting cost decreases with the offered waiting times associated with the announcements. The results of our counterfactual analysis show that it may not be necessary to provide announcements with very fine granularity.

This paper was accepted by Yossi Aviv, operations management.
Length-weight relationship and population genetic of two marine gastropods species (Turbinidae: Turbo sparverius and Turbo bruneus) in the Bird Seascape Papua, Indonesia
Authors: SALEKY DANDI , SETYOBUDIANDI ISDRAJAD , TOHA HAMID A. , TAKDIR MUHAMMAD , MADDUPPA HAWIS H.
Published: March 2016

Length-weight relationship and population genetic of two marine gastropods species (Turbinidae: Turbo sparverius and Turbo bruneus) in the Bird Seascape Papua, Indonesia. Biodiversitas 17: 208-217. Turbo sparverius and Turbo bruneus are herbivorous grazers gastropod that lived on the rocky intertidal area, which have a role in maintaining algae on the intertidal ecosystem. Local people in Papua have exploited them for food and souvenirs. Even though this exploitation might affect their genetic diversity and population, a study of the genetic structure of these species has not been previously reported. This study aimed to analyze the morphometric, genetic diversity, population structure and connectivity of T. sparverius and T. bruneus in coastal water of West Papua, Indonesia. The results showed that the growth pattern of T. sparverius and T. bruneus in all populations were negative allometric, which means that weight gain was slower than length. Haplotype diversity value of all population T. sparverius and T. bruneus were 0.657-0.705 and 0.739-0.816, respectively. In addition, the haplotype diversity of eachÂ population showed a high level of diversity. The genetic structure was found in all population of T. sparverius and T. bruneus with F value-0.037-0.201 and 0.031, respectively. Population structure and phylogenetic tree showed the closeness of genetic due to gene flow between both T. sparverius and T. bruneus. Genetic distance value between populations T. sparverius and T. bruneus are very low were 0.002 and 0.003-0.004, respectively. High genetic similarity might occur due to condition and direction of current flow mediating ofÂ gene transport among population, and the similarity of habitats in each population.
Publishing Juan de Mena: an overview of the editorial traditions
Authors: Brocato Linde M.
Published: March 2016

This study traces the editorial traditions of the works of Juan de Mena from 1483 through 1590 and shows the geographical and chronological distribution of editions, paying particular attention to the mise en recueil of his poetic works. It then analyzes the mise en page of the editions, with particular analysis of the 1552 Antwerp editions. The article includes a catalog of editions with sigla according to the norms of the CIM project, and two tables comparing editorial production by work and year, and the distribution of editions by place.
Da articulación textual nos testemuños da lírica profana galego-portuguesa
Authors: Fernández Guiadanes Antonio
Published: March 2016

Na presente contribución lévase a cabo unha primeira aproximación á estruturación xerarquizada que presentan os contidos textuais (cantigas) nalgúns dos relatores que nos legaron a lírica profana galego-portuguesa, isto é, cómo se delimita cada cantiga e as partes que a compoñen. Esta descrición da diuisio textus permitiranos en moitas ocasións poder discernir entre un plano xeral de obra (cancioneiro, folla ou mesmo antígrafo) e un plano particular en que afloran as particularidades de copia de cada un dos amanuenses que interviñeron no proceso de copia; estes deron conta, probablemente, dunhas directrices preconcibidas que, ó seren abandonadas en certos momentos puntuais, puideron ocasionar evidentes erros. Ser conscientes da ordinatio dos contedores que conservaron a tradición lírica, poder chegar a percibi-los desvíos debidos ós axentes encargados de poñer por escrito estes textos e ser quen de remontarnos ó antecedente e á súa posible estruturación constitúe o único camino cara á formulación de hipóteses de traballo a nivel textual dun alto grao de fiabilidade.
«Atiérrame el porvenir»: la Confesión de Juan Fernández de Heredia
Authors: D'Agostino Maria
Published: March 2016

El artículo es un primer paso hacia el estudio exhaustivo de la producción religiosa de Juan Fernández de Heredia. La poesía de uno de los más importantes representantes de la corte de Germana de Foix no ha sido, sino en años recientes, objeto de análisis pormenorizado y menos lo han sido sus composiciones religiosas. En efecto, los textos devotos de Fernández de Heredia son un número exiguo frente a su amplia producción de tema amoroso y de tipo tradicional. Sin embargo, a pesar del número reducido de composiciones, la poesía religiosa de don Juan se imprimió por primera vez seis años antes de que saliera la editio princeps de sus Obras en 1562, puesto que vio la luz en 1556 en la primera edición española del Cancionero de Jorge de Montemayor. El objetivo del trabajo es averiguar qué tipo de textos religiosos escribió Fernández de Heredia y, sobre todo, si su poesía devota es asimilable, y en qué medida, a la producción de finales del xv principio del xvi del mismo ámbito temático o si presenta —como hemos intentado demostrar en trabajos anteriores a propósito de su poesía amorosa—, frente a esa tradición diferencias, en algunos casos especialmente relevantes, procedentes de la gran tradición lírica valenciana cuya cumbre es Ausiàs March. El artículo se centra especialmente en el análisis de la Obra exhortando la obligación que el cristiano tiene de confesar y lo que debe hacer —o, mejor dicho, la Confesión— y demuestra, una vez más, que Juan Fernández de Heredia funde en sus versos tradiciones poéticas diferentes fijando su mirada, también en este caso, en la producción de su gran coterráneo, en concreto en el Cant espiritual, texto con el que el poema de don Juan comparte el dramático tema de la contritio y de la dificultad de llegar a un sincero arrepentimiento y en cuyos versos es posible detectar en más de una ocasión la fuente directa de nuestro poeta.
Estudio de variantes y adiciones del Laberinto de Fortuna
Authors: Moreno Manuel
Published: March 2016

Este artículo es la introducción y estudio de la edición crítica de Las XXIV (ID 4672, ID 6076, ‘Como durmiendo con la pesada’), ‘segunda adición’ al Laberinto de Fortuna de Juan de Mena. En este estudio se abordan los problemas de transmisión de Las XXIV y cómo a partir de las tradiciones manuscritas e impresas se pretende que tres composiciones formen un solo cuerpo: Al muy prepotente don Juan el segundo (ID 0092, Laberinto de Fortuna), La Flaca barquilla (ID 1808, tres coplas, ‘primera adición’) y Como el que duerme con la pesada (ID 4672, ID 6076, Las XXIV, ‘segunda adición’). El estudio de los enlaces entre las tres composiciones, la edición de ID 1808, el estudio de: las variantes, los componentes de la glosa (resúmenes, vocabulario e intertextualidad), así como de la historia editorial de la transmisión de Las XXIV, completan el estudio.
Ramblings of an old academic: Unconfident advice for end-times academics
Authors: Gee James Paul
Published: March 2016

The last person anyone should take advice from about how be an academic today is me. First, I am a Baby-Boomer. We Baby-Boomers let colleges and the rest of the world go to hell in a handbasket on our watch. Second, . . . [download the PDF below and read more]