bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of interval hypoxic therapy in the hypoxia-hyperoxia mode on the hemostatic system of patients who have suffered a new coronavirus infection COVID-19
Authors: Misirova Indira A. , Tsuntaev Omari-Butta A. , Merzhoeva Madina V. , Merzhoeva Makka V. , Borukaeva Irina Kh.
Published: September 2023

Background. The positive effect of interval hypoxic therapy in the treatment of many diseases has become the basis for its use in rehabilitation after a new coronavirus infection to normalize disorders of the hemostatic system.
Aim. To identify the peculiarities of the interval hypoxic therapy effect on the hemostatic system of patients who have suffered a new coronavirus infection.
Material and methods. The work was carried out from April 2020 to May 2022. 220 men aged 4559 years (average age 48.82.4 years) were examined. The main group included 90 people who had a moderate coronavirus infection a month ago; the control group (n=70) was represented by relatively healthy people; the comparison group (n=60) suffered coronavirus infection and underwent standard rehabilitation without hypoxic therapy. The content of platelets, D-dimer, international normalized ratio, prothrombin time, activated partial thromboplastin time, antithrombin III activity, interleukin-6 level, and C-reactive protein content in the blood serum was determined. To assess statistically significant differences, a parametric method applying paired and unpaired Student's t-test was used. Differences were considered statistically significant at p 0.05.
Results. In patients of the main group, a violation of the hemostatic system, indicating increased thrombogenicity of the blood against the background of persistent inflammatory activity, was revealed. After interval hypoxic therapy, the platelet count increased to 215.5323.57109/l (p=0.035), activated partial thromboplastin time to 26.741.84 s (p=0.035), international normalized ratio to 0.890.06 (p=0.005), antithrombin III activity in the blood up to 81.814.33% (p=0.007); the level of fibrinogen decreased to 3.861.09 g/l (p=0.035) and the content of D-dimer in the blood to 255.5817.36 ng/ml (p=0.035). There was a decrease in the level of interleukin-6 to 6.030.65 pg/ml (p=0.035) and C-reactive blood protein to 1.030.15 mg/l (p=0.035).
Conclusion. Interval hypoxic therapy had a normalizing effect on the hemostatic system of patients who suffered a new coronavirus infection, as a result of suppressing the inflammatory process in the body.
Premature birth. Successes and failures
Authors: Fatkullin Ildar F.
Published: September 2023

518% of pregnancies end in premature birth, defined as birth before 37weeks of gestation. Every year, 15,000,000babies are born prematurely worldwide, of which more than 1,000,000die due to complications associated with prematurity. Their contribution to neonatal and infant mortality is significant (70 and 36%, respectively). Premature birth is a syndrome characterized by many etiological factors, such as intra- and extrauterine infections, decreased excretion and decreased reception of progesterone, uterine overdistension, cervical factor, stress and a number of other, sometimes unknown, reasons. Over the past decade, some progress has been made in predicting and preventing spontaneous preterm birth. The main method for predicting and diagnosing the threat of premature birth is transvaginal ultrasound cervicometry in the second trimester of pregnancy (1424weeks). The length of the sonographically measured cervix is the most accurate prognostic criterion for assessing the risk of preterm birth, especially in pregnant women at risk (history of preterm birth). Vaginal administration of micronized progesterone reduces the risk of preterm birth in women with a short cervix. Diagnosis is based on taking into account clinical symptoms, cervical length and biochemical tests that determine placental proteins. Hospitalization in a perinatal center or levelIII institutions, which include intensive care units and the second stage of nursing newborns, serves as the basis for the effective organization of medical care for premature birth. When indications for surgical delivery are indicated, preference should be given to a cesarean section with the extraction of a low-weight fetus in the entire amniotic sac. The article also reflects the contribution of the staff of the Department of Obstetrics and Gynecology named after prof.V.S.Gruzdev of Kazan State Medical University in solving the problem of premature birth.
Post-marketing surveillance study to compare the efficacy and safety by investigating the combination of Vitamin C, Vitamin E, Lutein, Zeaxanthin, Zinc and Copper with the combination of Astaxanthin, L-Glutathione and Lutein (contains Zeaxanthin) in patients of dry age-related macular degeneration (AMD)
Authors: Pawaskar Lalit , Kiran Mayuresh , Sharma Amit , Kiran Mayuresh
Published: September 2023

To determine the comparative efficacy and safety of Investigational Product – 1 (combination of Vitamin C, Vitamin E, Lutein, Zeaxanthin, Zinc and Copper) with Investigational product 2 (combination of Astaxanthin, L-Glutathione and Lutein (contains Zeaxanthin)) in patients for the indication of dry age-related macular degeneration (AMD).

It was an academic, prospective, open labelled, parallel, randomized, multicentric, comparative post-marketing surveillance study. The study was conducted at 5 clinical trial sites with 40 patients at each site. Patients with confirmed diagnosis of dry AMD in right or left or both eyes who met study inclusion and exclusion criteria were recruited for the study. The study duration was of 365 days and during the same patients were asked to visit the clinical trial site on day 30, 180 and 365 for the safety and efficacy assessment. Visual acuity, vision related quality of life and visual impairment questionnaire were the efficacy assessment parameters evaluated.

Total 181 patients completed the study. It was found that there was statistically significant difference in the patients treated with the investigational product 1 and 2 for the efficacy assessment parameter, visual acuity (p value 0.0102) and vision related quality of life (p value 0.0013) and for visual impairment questionnaire score, no statistically significant difference was found (p value 0.0747).

Investigational product 1 was found to be more efficacious as compared to investigational product 2 for the efficacy assessment parameters visual acuity and vision related quality of life. Whereas for visual impairment questionnaire score i.e. vision required for the daily work, both products were found to be equally efficient.
Assessment of anaemia and hyperglycaemic status in progression of diabetic retinopathy along with macular changes: A case control study
Authors: Bhattacharya Ankita , Banerjee Sadajit , Biswas Indira Bhaskar , Maity Ashok Kumar
Published: September 2023

: Diabetes-related visual impairment is preventable through control measures. As diabetic retinopathy and maculopathy lack effective treatment, prevention is key. This study examines glucose, HbA1c, and hemoglobin to assess their impact on disease development and severity.

Study includes 100 case (diabetic retinopathy) and 100 control (diabetes without retinopathy)subjects. Further, case group was subdivided into subgroups according to its severity and depending on the presence of maculopathy. Thereafter, values of different renal parameters were compared between these sub groups.

The mean FBS and PPBS values significantly correlate with diabetic retinopathy (DR) severity (P<0.001 for FBS, P=0.012 for PPBS). Uncontrolled diabetes compounds DR risk. All very severe NPDR and PDR patients had HbA1c >7.0. No significant relationship between HbA1c and DR severity (P=0.302) was found. Elevated HbA1c in cases (P<0.001) underscores hyperglycemia's role. CSME, F/PP blood sugar, and HbA1c show no significant correlation. DR group has higher anemia likelihood (P=0.001), increasing with severity (P=0.017). Hemoglobin's relation to CSME is statistically insignificant.

Elevated FBS, PPBS, and HbA1C levels in diabetic retinopathy (DR) cases link hyperglycemia to DR development. Severity correlates with these parameters. HbA1C rises notably in severe NPDR and PDR. Anemia risk increases, but CSME shows no significant correlation. Monitoring biochemistry is vital due to limited DR treatment options.
Pandemia to także szansa – o pozytywnych zmianach w wymiarze indywidualnym i społecznym
Authors: Zbyrad Teresa
Published: September 2023

Powszechnie zwraca się uwagę na negatywne skutki pandemii. Jednak jak każde zjawisko społeczne, pandemia COVID-19 oprócz skutków negatywnych, przyniosła także pewne skutki pozytywne. Jednak te ostatnie mają mniejszą skalę, ale i paradoksalnie ogromną wartość dla jednostki i rodziny. W swoim artykule skupię się na pozytywnej stronie, ukazując pandemię w zupełnie innym świetle, która dla wielu ludzi oprócz niszczącej siły spustoszenia, stała się szansą na zmianę pozytywną. Czy pandemia może być szansą? Czy zło, które przyszło wraz z wirusem, dziesiątkujące ludzkość, przynoszące śmierć i cierpienie milionów ludzi, rodzące strach – czy to zło mogło zrodzić jakieś dobro? Czy ten totalny i globalny kryzys w wymiarze społecznym, gospodarczym, zawodowym, rodzinnym i osobistym mógł przełożyć się na umocnienie, rekonstrukcję, odbudowę i rozwój tożsamości? Oto pytania, na które postaram się odpowiedzieć.
A Verdant Ethnography: Henry Green, Navajo Poetry, and Dialogical Ethnopoetics
Authors: Webster Anthony
Published: September 2023

The endeavour here is to write an ethnography with a sense of living. Using the literary work and theories of Henry Green, as well as concerns with dialogical anthropology, a discourse-centred approach to language and culture (conjoined here as a dialogical ethnopoetics), and Navajo rhetorical practices, I present an aggregate of transcripts from several conversations with Navajo poets over the years. It is the transcripts that give life to ethnography. The first part places this endeavour in an intellectual context; the much longer second part gives the verdant ethnography. A verdant ethnography is predicated on an empirical foundation (transcripts), but also on an obliqueness as well (the stuff of talk).
The Physiological Effects of ASMR on Anxiety
Authors: Seifzadeh Sahar , Asayesh Vahid , Nikjeh Majid Torabi , Dehghani Mahdi , Parsa Elham Rabbani , Asgharianasl Fatemeh
Published: September 2023

Purpose: Autonomous Sensory Meridian Response is a novel phenomenon that is very popular these days on Youtube and Reddit to its anti-anxiety effects. As the name suggests, ASMR is a relaxing warm sensation that begins on the scalp and spreads throughout the body. This technique is also known as "brain massage," and it relies on soothing sights and sounds, like whispers and slow movements. Investigating these videos is primarily motivated by the desire to determine their scientific origins, which can be derived from a variety of approaches.
Materials and Methods: In this paper, we intended to examine the physiological changes such as Heart Rate (HR) as well as Galvanic Skin Conductance (GSC) levels before and after watching a single session ASMR video.
Results: The dependent t-test statistical analysis by SPSS results with P-value <=0.01 indicated that after a single session of ASMR watching, the heart rate decreased significantly comparing the baseline data. In addition, the skin conductance was slightly reduced as well, but not significantly.
Conclusion: These physiological findings prove that ASMR could be an affordable, portable, and immediate anxiety relief for those struggling with anxiety-based disorders, especially for patients who do not respond well to medication or seek alternatives to anti-anxiety medications due to the wide range of side effects or would like to try it for better results along with the prescribed drugs.
Decomposition of Displacement Field into the Irrotational and Solenoidal Component Using Fast Fourier Transform
Authors: Gorji Reza Bahrami , Mohammadi Mohammad , Makkiabadi Bahador
Published: September 2023

Purpose: A new code based on Helmholtz decomposition is presented to separate longitudinal (pressure) and transverse (shear) components of a mixed wave field. This algorithm will help isolate shear or pressure components of an elastic wave to further concentrate on each specific wave and its physical characteristics, particularly in medical imaging instrument development and image processing techniques.
Materials and Methods: Using the combination of Fourier transform and Helmholtz decomposition, first, the mathematical basis of the work is prepared. After reaching a usable formula, this basis is embedded in the Code written in MATLAB program. Then, various test data containing shear and pressure waves were created and fed to the Code to evaluate its ability to decompose the displacements into the shear and pressure waves.
Results: This new algorithm successfully isolated the transverse and longitudinal wavefront of the mixed wavefield. The Code demonstrated 100% accuracy for separating the shear wave and more than 99% for the pressure wave. Moreover, the background noise was kept under 0.03% in every step.
Conclusion: The results show that using Helmholtz decomposition in Fourier space on 3D data can help decompose a displacement field into its irrotational and solenoidal components with high accuracy. A weak dependency on wave thickness and contrast was observed, but the algorithm's accuracy never fell below 99%.
Improper Use of Traditional Medicine “Anbar Nesara” for Wound Infection: A Case Report
Authors: Dastjerdi Marzieh Vahid , Ghahghaei-Nezamabadi Akram , Tehranian Afsaneh , Mansouri Parisa , Hosseini Ladan
Published: September 2023

In Iranian traditional medicine, donkey dung, known as "Anbar-Nesara" is used for its antimicrobial and antiallergic properties. Incorrect medical beliefs can lead to the incorrect use of complementary medicine and the creation of unnecessary harmful effects. Although there have been many reports about the traditional medical benefits and the use of Anbar-Nesara, we describe a woman with severe wound infection following surgical and administration of Anbar-Nesara smoke.
Indicadores de sustentabilidade e a ferramenta IDEA: Um estudo de caso em uma propriedade rural familiar de Uruguaiana, Rio Grande do Sul
Authors: Goñi Liana Mendonça , Lopes Marcio R. Caetano de Azevedo , Bahr Gustavo Conceição , Schimitz Débora Andréia , Bruch Christian Alan
Published: September 2023

Para promover uma análise sobre a sustentabilidade em um determinado sistema de produção, torna-se fundamental levar em consideração uma abordagem que considere, minimamente, indicadores sociais, ambientais e econômicos.Neste tipo de levantamento, os índices de sustentabilidade apresentam-se enquanto resultados gerados por instrumentos de diagnóstico, a fim de possibilitar a coleta e a interpretação de informações. Assim, o presente artigo tem como objetivo demonstrar a utilização da ferramenta de Indicadores de Sustentabilidade das Explorações Agrícolas (IDEA) em uma propriedade rural familiar. A ferramenta IDEA leva em consideração as dimensões agroambiental, sócio-territorial e econômica. A partir do diagnóstico foi possível evidenciar que apesar de a ferramenta apresentar lacunas, constitui-se enquanto importante instrumento de análise, evidenciando que a propriedade objeto deste estudo possui baixos índices de sustentabilidade, necessitando a intervenção e correção de alguns pontos cruciais para que alcance níveis mais satisfatórios de sustentabilidade.
Algoritmi nad velikimi količinami podatkov LiDAR
Authors: Žalik Borut , Lukač Niko , Mongus Domen
Published: September 2023

V članku predstavimo postopke obdelave velikih količin nestrukturiranih geometrijskih podatkov, pridobljenih s prebirniki LiDAR. Najprej opišemo postopke klasifikacije točk LiDAR v točke, ki ležijo na Zemljinem površju. Opravimo kratek pregled obstoječih metod nato pa na kratko predstavimo našo metodo, temelječo na konceptih matematične morfologije. V nadaljevanju predstavimo zanimivo aplikacijo klasificiranih podatkov LiDAR za določitev sončevega potenciala streh v urbanih področjih. Podamo ključne parametre metode in predstavimo podatke za določitev sončevega potenciala in pridobljene električne energije iz treh različnih tipov celic za občino Beltince.
Zoltan Kerčmar, evangeličanski duhovnik in informator UDV
Authors: Rihtarič Ivan
Published: September 2023

Na Apaškem polju je živelo z ostalimi iz radgonskega okraja okoli 300 vernikov evangeličanske cerkve. Njihov položaj se je poslabšal v času druge svetovne vojne, ki jo je dokaj spretno vodil Zoltan (Zlatko) Kerčmar (1902-1962). Nova oblast ga je vključila v politično delo v kraju a ga je v začetku marca 1948 aretirala UDV zaradi klevetanja režima. Pod pritiskom je postal sodelavec UDV- informator s kodnim imenom »Matej«. Pisno je poročal o organiziranosti in delovanju vodstva cerkve v Pomurju ter o sedemnajstih družinah z apaškega območja. Poročal je, da so ljudje kritični do številnih ukrepov nove oblasti, predvsem na gospodarskem področju.
Izračunljivi modeli splošnega ravnovesja kot pomoč političnim odločevalcem
Authors: Dominko Miha , Primc Kaja , Slabe Erker Renata
Published: September 2023

Izračunljivi modeli splošnega ravnovesja (CGE-modeli) so v zadnjih 40 letih postali standardno orodje empirične ekonomske analize. K temu so pomembno prispevale izboljšave na področju računalniške tehnologije, ki so znatno zmanjšale stroške uporabe teh modelov za namen analize političnih odločitev ter s tem utrle pot njihovi razširjeni uporabi po celotnem svetu. Področje modeliranja izračunljivega splošnega ravnovesja je zahtevno, saj terja dobro poznavanje ekonomske teorije, osnovnih računovodskih konvencij in ekonometričnih metod, razumevanje algoritmov reševanja ter obvladovanje pripadajoče programske opreme. Vendar pa dobro poznavanje vsega naštetega nima veliko pomena, če razvijalec modela svojih rezultatov ni sposoben pojasniti na dovolj razumljiv in prepričljiv način, da so nato uporabljeni v praksi. Oviro pri implementaciji rezultatov velikokrat predstavlja tudi nezaupanje v modele, ki je posledica slabega poznavanja njihovega delovanja, zato je namen pričujočega prispevka osvetliti osnovne lastnosti in zakonitosti izračunljivih modelov splošnega ravnovesja.
Metafore v diskurzu o podnebnih spremembah v slovenskih, nemških in madžarskih medijih
Authors: Larisa Fabčič Melanija , Bernjak Elizabeta
Published: September 2023

Varovanje podnebja je v domačem in mednarodnem javnem razmišljanju postalo središče pozornosti že pred nevarno situacijo, ki jo je povzročil koronavirus. Virus in vojna v Ukrajini pa sta močno spremenila politično agendo in postavila varnostna vprašanja na prvo mesto, pred boj proti podnebnim spremembam. Globalno segrevanje in podnebne spremembe mnogi dojemajo kot znanstveno dokazano dejstvo, ki ga povzročajo številne človekove dejavnosti, podnebni skeptiki pa dvomijo o obstoju podnebnih sprememb in človekovem vplivu nanje. V prispevku obravnavamo diskurz o podnebnih spremembah v slovenskih, nemških in madžarskih medijih, fokus je na diskurznih akterjih s področja politike, znanosti in medijev. Zanima nas, kako so prikazane podnebne spremembe in kateri metaforični okviri prevladujejo v poročanju o njih. Pri tem se naslanjamo na kognitivno teorijo metafore Lakoffa in Johnsona (1980) ter Steenov (2008) tridimenzionalni model metafore. Pri analizi diskurza se opiramo na metodo kritične analize diskurza (Fairclough in Wodak 1997, van Dijk 1999).
Radiološke spremembe pljuč pri COVID-19 pljučnici
Authors: Šantl Letonja Marija , Meolic Anamarija
Published: September 2023

Radiogram pljuč in srca (RTG PC) in slikanje prsnih organov z računalniško tomografijo (CT) imata pomembno vlogo pri diagnosticiranju, prikazu začetnih sprememb in sledenju bolnikov, ki so okuženi z virusom SARS-CoV-2. RTG PC je manj občutljiva preiskava, a je hitra, enostavna in jo lahko opravimo ob bolniški postelji, obenem pa predstavlja zlati standard za kontrolo sprememb v pljučih bolnikov z COVID-19 pljučnico. CT ima visoko občutljivost v diagnosticiranju COVID-19 pljučnice. Infiltrati mlečnega stekla in konsolidacija pljučnega parenhima so glavne spremembe, ki so vidne na CT. Razporeditev infiltratov je tipično obojestranska in periferna. Manj tipične spremembe so plevralni izliv, kavitacije, pnevmomediastinum in pnevmotoraks.
Šipon je avtohtono ime, ni pa avtohtona sorta
Authors: Šikovec Slavica
Published: September 2023

Bela vinska sorta ŠIPON je bila k nam prinesena iz severne Italije- Piemonte, za časa pohoda rimskih legij, preko našega ozemlja, proti severu Evrope. Zaradi boljše oskrbe vojske z vinom, so Rimljani pospeševali vinogradništvo, lepega dela Evrope. Sorta FIORI MONTE je prav na območju ljutomerskih hribov našla ekološke danosti kjer je lahko trta optimalno razvila svoj genski kakovostni potencial; saj je vino kot »Echte Luttenberger« (Žlahtni Ljutomerčan) bilo na dvorih Avstrije, zelo cenjeno . Leta 1948 so vsa državna vinogradniška posestva pri nas pričela s pozitivno nato negativno in končno s klonsko selekcijo. Klone odlikuje visoka rodnost, ki jo je potrebno regulirati z manjšo obremenitvijo trte, pri rezi, če želimo pridelati vino vrhunske kakovosti. Zato pa sorta ŠIPON ni avtohtona sorta ampak je ŠIPON ORIGINALNO NAŠE IME , ki ima korenine v vzklikih »si bon,« francosko govorečih Križarjev. To so domačini zaselka Jeruzalem osvojili kot ŠIPON.
Povezava med konceptualnim pristopom pri poučevanju fizike in rezultati raziskave TIMSS
Authors: Ülen Simon
Published: September 2023

Osnovni cilj konceptualnega pristopa pri poučevanju fizike je globlje razumevanje fizikalnih konceptov. V prispevku predstavljamo temeljne zakonitosti konceptualnega pristopa pri poučevanju fizike in ključne karakteristike mednarodne raziskave trendov znanja matematike in naravoslovja za maturante 2015 - Trends in International Mathematics and Science Study, Advanced (TIMSS). V osrednjem delu prispevka predstavimo rezultate raziskave na izbrani slovenski gimnaziji in jih analiziramo v povezavi z uporabo konceptualnega pristopa.
Reverzibilno računalništvo
Authors: Meolic Robert
Published: September 2023

Današnji računalniki delujejo tako, da so števila in podatki predstavljeni z dvojiškim sistemom, računanje pa je izvedeno kot zaporedje Boolovih operacij. Ta model je mogoče zelo dobro udejaniti s pomočjo električnih signalov. Ker želimo vedno manjše in hitrejše računalnike pa danes raziskovalci raziskujejo tudi radikalno drugačne tehnologije kot je npr. kvantni računalnik. Pomembna teorija na poti do novih temeljev računalništva je teorija reverzibilnega računalništva. Reverzibilna vezja imajo lastnost, da delujejo v obeh smereh, torej lahko nastavimo vrednosti na izhodni strani, rezultat pa dobimo na vhodni strani. V tem prispevku podamo matematične osnove potrebne za načrtovanje takšnih vezij.
Čebelarstvo kot poslovna priložnost za Pomurje
Authors: Kapun Stanko
Published: September 2023

Čebelarstvo se je na območju Pomurja v zadnjih petnajstih letih močno razvilo. Naravne danosti in neokrnjena narava v pokrajini ob Muri, dajejo raznotere možnosti na področju pridelovanja medu, vzreje čebeljih matic, čebeljih družin, pridobivanja peloda, matičnega mlečka, surovega propolisa in čebeljega voska. Zanimanje med mladimi je vedno večje, to dokazuje dejstvo, da se je v zadnjih treh letih iz območja Pomurja vpisalo na osnovni tečaj iz čebelarstva preko 200 slušateljev, ki so tečaj uspešno opravili.
Akademik Anton Vratuša – med znanostjo in politiko
Authors: Toplak Ludvik
Published: September 2023

Dr. Anton Vratuša je bil prvi akademik, ki je imel korajžo, da je javno spregovoril v prid razvoja na otvoritvi visokošolskega študija v Pomurju. V imenu njegovega dela in rezultatov vsega njegovega truda, želim s hvaležnostjo nanizati nekaj osebnih in dragocenih izkušenj.
Papir izdelan iz japonskega dresnika
Authors: Gregor Svetec Diana , Možina Klemen
Published: September 2023

Poleg lesnih vlaken se za izdelavo papirja lahko uporabljajo tudi vlakna enoletnih in večletnih rastlin. V prispevku je kot alternativna surovina za izdelavo papirja predstavljen japonski dresnik. Japonski dresnik je ena izmed najbolj invazivnih tujerodnih rastlinskih vrst v Evropi in Sloveniji. Projekt Mestne občine Ljubljana APPLAUSE »Od škodljivih do uporabnih tujerodnih rastlin z aktivnim vključevanjem prebivalcev« naslavlja nerešena vprašanja glede ravnanja z invazivnimi tujerodnimi rastlinami v smislu pristopa brez odpadkov in krožnega gospodarstva. Ena izmed tovrstnih rešitev je, pridobivanje papirnih vlaken iz olesenelega stebla rastline. V okviru projekta je tako bil na pilotnem papirnem stroju na Inštitutu za celulozo in papir (ICP) izdelan papir, ki vsebuje 55 % vlaken japonskega dresnika, ostalo so lesna vlakna. Papirju so bile določene osnovne, površinske in mehanske lastnosti papirja, z namenom ugotoviti uporabnost tovrstnega papirja. Preliminarna raziskava je pokazala, da bi se japonski dresnik lahko uporabljal v papirni industriji za izdelavo posebnih, majn zahtevnih vrst papirjev.
Ewolucja ochrony konsumenta w przypadku braku zgodności towaru z umową. Uwagi w kontekście implementacji dyrektywy 2019/771 w sprawie niektórych aspektów umów sprzedaży towarów do prawa polskiego
Authors: Dąbrowska Wiktoria , Zań Natalia
Published: September 2023

20 maja 2019 r. została uchwalona Dyrektywa 2019/771 Parlamentu Europejskiego i Rady, która wprowadziła wiele zmian w zakresie ochrony praw konsumenta oraz sprzedaży konsumenckiej. Dostosowanie dotychczasowych przepisów prawa polskiego oraz wprowadzenie nowych tak, by odpowiadały celom wspomnianego wyżej aktu stanowiło niemałe wyzwanie legislacyjne, które prowadziło do różnych wątpliwości. Niniejsza praca ma na celu przegląd tej problematyki, zwracając szczególną uwagę na zmiany dotyczące ochrony konsumentów oraz instytucji rękojmi.
MATHEMATICAL MODELING OF POROUS GEOMETRICALLY NONLINEAR METAL NANO-PLATES TAKING INTO ACCOUNT MOISTURE
Authors: Krysko Anton V. , Kalutsky Leonid A. , Zakharova Alena A. , Krysko Vadim A.
Published: September 2023

Link for citation: Krysko A.V., Kalutsky L.A., Zakharova A.A., Krysko V.A. Mathematical modeling of porous geometrically nonlinear metal nano-plates taking into account moisture. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 9, рр. 36-48. In Rus.
The relevance.  The study of stress-strain behaviour and bearing capacity of porous metallic nanoplates, especially under extreme conditions and taking into account large deformations, is of great importance. These structures have a wide range of practical applications, for example, to clean solid fractions in wells during their setting up and to ensure fluid flow during operation. In addition, porous metal filters in the form of plates can serve as effective filters for removing solids from production wellbores, especially in the bottomhole zone. The versatility of these materials extends to various industries including aerospace, medical and instrumentation, indicating their potential to solve critical problems and advance technologies in various fields. The main aim of the research is to develop a new model of porous nanoplates, taking into account moisture, which would describe the real work of the studied objects in the oil and gas industry and other industries; to construct the efficient and fast methods for studying porous metallic nanoplates. Methods: variational iterations method, an extended Kantorovich method, which has high accuracy of solution of nonlinear problems and fast performance. The correctness of application of this method is conditioned by the proof of its convergence theorems belonging to the authors. In addition, the obtained solutions are compared with the solutions obtained by the Bubnov–Galerkin method in higher approximations and by the finite difference method of the second order of accuracy, as well as with the solutions obtained by other authors. Results. A model of porous flexible nanoplates is constructed taking into account moisture. Nano effects are described by the modified moment theory of elasticity. The method of variational iterations is further developed for the study of the stress-strain state of porous metallic nanoplates at large deflections. The paper analyzes the types of material porosity, size-dependent nano parameter, moisture distribution, porosity index and boundary conditions on the bearing capacity of porous metal plates. The type of porous material with the highest bearing capacity is identified.
Tamm-Horsfall Protein Expression in Urine of Buffaloes at the Estrus and Diestrus Stages of Estrous Cycle
Authors: Varra Manasa , Sundaresan N.R. , Kumar V. Girish , Chandranaik B.M. , Sejian Veerasamy , Sudha G. , Suchitra B.R.
Published: September 2023

Background: Identifying buffaloes in estrus is crucial for enhancing the efficiency of reproduction as silent heat is a major concern in this species. Review of literature indicated the role of Tamm-Horsfall protein (THP) is associated with the physiological events around the estrus stage. Hence, the present study was aimed to quantify the expression level of THP in urine of buffaloes to ascertain its suitability as a marker for identifying buffaloes in estrus. Methods: The grouping of animals as mid-diestrus (Group-I/G-I/Control group), regular estrus (Group-II/G-II) and silent estrus (Group-III/G-III) buffaloes was done using a combinatorial approach. The expression of THP in the urine of three groups of animals was quantified by western blot. Result: The results of the present study revealed higher levels of urinary THP in G-II animals when compared to G-III and G-I animals, although it was statistically non-significant (p greater than 0.05). The present study revealing for increased urinary expression of THP in G-II and G-III animals when compared to G-I animals probably construes the antimicrobial role of THP in the female reproductive tract and its role during estrus to prevent microbiota population beyond the physiological levels. For THP to be considered as biomarker for detecting buffaloes in silent heat there is need for further studies involving large number of animals. Nonetheless, an easy method has been developed that facilitated THP detection and quantification in urine of buffaloes by western blot.
The Etiology of Primary infertility in the Population of Kashmir Valley, India
Authors: Ahmed Khan Latif , Wani Mahmooda , Ahad Afroza , Latif Roman
Published: September 2023

Objective: To study the etiology of primary infertility in the population of Kashmir Valley, India. Design: A prospective study was undertaken of the couples who attended the clinic of the author over a period of 4 years, 2012 to 2016 for Consultation of Primary Infertility. Setting: This was study done in a community hospital. All patients who attended our hospital for infertility over a period of 4 years. A NICE protocol was followed for the evaluation. Ethical committee permission was obtained for this study. Patient Population: Couples married for at least 1 year and those who had regular unprotected sexual intercourse. Process of Study: A longitudinal study protocol was followed to identify the cause of infertility. Results and outcome: A predominant female factor was identified in 74% of the couples. Predominant male factor was identified in 7.8 % males and in all others, there was either a male as well as female factor or no male factor at all. Complete azoospermia was seen in 7.8% of the screened men and 18% showed some abnormality. Among females. 37.2% % showed evidence of anovulation (mostly Polycystic Ovary disease), 14.89% had hypothyroidism, 7% showed some sort of uterine abnormalities like malformed uterus, uterine septa or massive fibroids in uterus, and 6.3% of the patients showed tubal abnormalities. Conclusion: Polycystic ovary disease, either unrecognized or untreated is most common cause of infertility followed by hypothyroidism and uterine issues. Tubal blockage is not the common etiology as seen in most of the western world. Male factor like azoospermia does occur and sperm abnormalities are a common cause in our setting but not the sole factor for subfertility.
Effect of Prolonged GnRH Agonist Therapy Prior to Frozen Embryo Transfer on IVF-ET Outcome in Patients with and without Endometrioma Surgery
Authors: Uludag Semih Zeki , Yurci Arzu , Turktekin Nurettin
Published: September 2023

Objective: It remains to be clarified whether prolonged Gonadotrophin-Releasing Hormone agonist (GnRHa) administration before frozen embryo transfer to patients with and without endometrioma resection improves reproductive outcome. This study was designed to investigate freeze-all cycles with subsequent prolonged GnRHa administration in patients with and without endometrioma surgery. Method: A total of 164 patients with complaints of infertility and diagnosed with endometrioma were included in this case controlled study. Endometrioma resection was performed in 65 out of 164 women and then Controlled Ovarian Stimulation (COS) was performed (Group 1). Fresh embryos were transferred to 40 of 65 patients who underwent endometrioma surgery. Embryos were vitrified in 25 patients and administered leuprolide acetate 3.75 mg for 3 months. The remaining 99 patients were referred directly to the COS without any surgery for endometrioma (Group 2). While fresh-ET was applied to 49 of 99 cases, embryos were frozen in the remaining 50 cases. Subsequently they were administered leuprolide acetate 3.75 mg for 3 months. Primary outcome was Clinical Pregnacy Rates (CPR), Ongoing Pregnancy Rates (OPR), and Live Birth Rates (LBR). Results: No significant difference was found between the operated and non- operated groups in terms of CPR, OPR and LBR between patients who received fresh-ET. While there was no significant difference in CPR and OPR in operated and non-operated groups who underwent frozen-ET, LBRs were found to be significantly higher in patients who were not operated (p<0.01). Making fresh-ET or frozen-ET in patients who underwent endometrioma surgery did not significantly affect CPR, OPR and LBR. Making frozen-ET in patients who did not undergo surgery significantly increased both CPR (p <0.02) and OPR (p<0.03). Conclusion: Prolonged use of GnRH agonist treatment before frozen-ET in patients without endometrioma surgery resulted in significantly higher clinical and ongoing pregnancy rates than did patients with endometrioma surgery.
Medico-Surgical Therapeutic Management of Benign Prostatic Hyperplasia
Authors: Mega Obukohwo Oyovwi
Published: September 2023

Although benign prostatic hyperplasia (BPH), a condition that affects many elderly people, is frequent, surgical treatment for BPH has advanced significantly in comparison to medicinal care. Instead of addressing the disease itself, medical treatment just addresses the symptoms. Due to the fact that the majority of senior patients will have comorbid conditions like diabetes and hypertension, surgery may not be an option for everyone, making medical care more widely available. Notably, even while TURP, TUIP, TVP, TUMT, and TUNA continue to be the gold standards for treatment, medicinal therapy still offers hope for recovery and averting surgery. But one must be aware of the recently identified negative effects that these drugs can have in the elderly male, especially over a lengthy period of time. Though they are not appropriate for every patient, novel minimally invasive procedures have shown promise for the elderly male who has failed medicinal therapy but is not a surgical candidate or wishes to avoid surgery. Before choosing a course of treatment for your BPH patient, it’s crucial to talk with them about the risks, advantages, side effects, and alternatives.
Stem Cells In IVF: Hope or Hype?
Authors: Hollands Peter
Published: September 2023

Perhaps the most obvious link to IVF and stem cells is the development of human Embryonic Stem Cells (hESC) from the inner cell mass of human embryos [4]. Whilst hESC are pluripotent and therefore an excellent candidate for gamete production, very little progress has been made because of the legal, ethical, moral, and religious objections to creating hESC which requires the destruction of a viable human embryo [5]. Induced Pluripotent Stem Cells (iPSC) have a similar history when it comes to IVF. These are somatic cells (e.g., skin cells) which are ‘transformed’ into pluripotent stem cells by the introduction of various genes [6]. These iPSC are pluripotent and autologous, so they have the ability, in theory, to be able to carry out gametogenesis in patients undergoing fertility treatment [7]. The problems with the routine clinical use of iPSC in fertility treatment is the cost but most importantly ongoing safety concerns about iPSC because of the genes needed to be inserted to convert a somatic cell into a stem cell [8]. Mesenchymal stem cells (MSC) can be obtained from adipose tissue, bone marrow, the umbilical cord and even inside teeth [9]. These MSC stem cells can produce bone, connective tissue and adipose tissue and there are some data suggesting that MSC may be useful in premature ovarian failure [10]. The drawbacks of using MSC in the treatment of infertility are the cost and the standardization of MSC to ensure safety and efficacy [11]. All these stem cell types have their problems when considering their use in the treatment of infertility. It may be many years, if ever, before they come to routine clinical practice in the treatment of infertility.
Herlyn-Werner-Wunderlich Syndrome: About an Uncommon Case Report
Authors: Mahtate Mariam , Lakhdar Khaoula , Cherradi Soukaina , Slaoui Aziz , Zeraidi Najia , Lakhdar Amina , Baydada Aziz
Published: September 2023

Herlyn-Werner-Wunderlich syndrome (HWWS), defined by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis, is a rare Mullerian duct malformation, usually diagnosed after menarche, when symptoms related to haematocolpos arise. HWW generally occurs at puberty and exhibits variable symptoms including pelvic pain shortly following menarche, dysmenorrhoea, palpable mass due to the associated haematocolpos or haematometra or haemoperitoneum due to retrograde menstruation. Ultrasonography and MRI are extremely useful in the diagnosis and classification of Müllerian duct anomalies. 3D ultrasound is more effective in the diagnosis of uterine malformation. Early detection of this relatively rare syndrome can lead to the provision of immediate treatment to preserve future fertility. We present a rare case report on Herlyn-Werner-Wunderlich syndrome from Morocco.
Sistema para el apoyo en la instrucción y seguimiento de las áreas de conocimiento evaluadas en la prueba PISA en la educación secundaria
Authors:   , Quispe Rosales Daniel Saul , Rodríguez Zarate Abel Sebastian
Published: September 2023

La calidad educativa en el nivel secundaria en el Perú es bajo comparado a los países vecinos de América del Sur, esto se evidencia en los resultados de la prueba PISA 2018. Aun así, estas pruebas también señalan que el Perú ha tenido una evolución positiva en sus puntajes obtenidos a lo largo del tiempo desde la prueba PISA 2009 hasta el 2018. Para complementar los esfuerzos realizados por el gobierno en mejorar la calidad educativa, se ha propuesto una aplicación web progresiva, que complemente el desarrollo de las competencias académicas del estudiante de secundaria y les permita alcanzar la línea base propuesta por la OCDE en las evaluaciones PISA. Esta aplicación está diseñada para los usuarios de estudiante y docente. Permitirá a los estudiantes practicar sus habilidades y consultar material de estudio y permitirá a los profesores evaluar y consultar informes del desempeño de sus estudiantes. Como resultados, esta aplicación demostró efectividad en incrementar al menos en un 40% el desempeño de los estudiantes en las áreas de matemáticas, ciencias, lectura y educación financiera.
El rol del fandom prosumer en la narrativa transmedia publicitaria de League of Legends
Authors:   , Herrera Paz Ariam Michael
Published: September 2023

League of Legends es uno de los videojuegos más populares del mundo y, debido a la gran variedad de contenido que genera en diversos medios, mantiene fiel a su audiencia. Gracias a ello, logró crear muchas comunidades de fans que, en la mayoría de los casos, participa en la creación de contenido de su universo. A estos fanáticos, que consumen y al mismo tiempo producen contenido, se les denomina prosumers y en esta investigación se buscó conocer cuál es el rol que ocupan en la narrativa transmedia publicitaria de League of Legends. La investigación se hizo bajo un enfoque cualitativo y un diseño fenomenológico. La muestra de este estudio estuvo compuesta por 15 fans/gamers del videojuego en cuestión, a los que se seleccionó mediante un muestreo por conveniencia entre participantes activos en sus comunidades. Asimismo, para responder a las preguntas de investigación, se realizaron entrevistas semiestructuradas, divididas en categorías. De todo ello, se obtuvo como principal hallazgo que el fandom prosumer cumple un rol de influencer en la narrativa transmedia publicitaria de League of Legends, ya que crea y comparte contenido con diferentes audiencias y plataformas, convirtiéndose en una suerte de publicidad gratuita y genuina para el videojuego.
Detecting Equine Herpesvirus-1 and Equine Herpesvirus -4 Infections in Racehorses using Polymerase Chain Reaction
Authors: TEKELİOĞLU Bilge Kaan , AKAY Ömer
Published: September 2023

The aim of this study was to use polymerase chain reaction (PCR) to detect and differentiate Equine Herpesvirus Type-1 (EHV-1) and Type-4 (EHV-4) viruses within the racehorse population in Türkiye. The diagnostic sensitivity of PCR was also assessed. For this purpose, 98 nasal swab specimens from naturally infected racehorses aged 2 and above, displaying respiratory symptoms suggestive of EHV infections, and 26 aborted fetuses with various organ samples were collected. DNA extraction and PCR analysis were performed on these samples. The study started with PCR optimization using reference strains of EHV-1 (89c25p) and EHV-4 (TH20p) DNA. Finally optimized was completed and reference strains were used for this study. In conclusion, PCR successfully detected and differentiated 7 EHV-1 positive samples from the tissues of the 26 aborted fetuses, as well as one EHV-1 positive and two EHV-4 positive samples from the nasal swabs of the 98 cases. This study represents one of the pioneering works where PCR was firstly employed to detect and differentiate EHV-1 and EHV-4 strains in Türkiye. The study's findings reveal the presence of both EHV-1 and EHV-4 in Türkiye's racehorse population and is among the early reports to identify the existence of EHV-4 using PCR. These findings underscore the circulation of both viruses within the racehorse population. As a result of this study, it has been concluded that the PCR method is a sensitive, cost-effective, and time-saving diagnostic approach for detecting and distinguishing EHV-1 and EHV-4 infections.
TÜRK BASININDA ÇERÇEVELEME MÜCADELESİ: AMASRA MADEN KAZASI HABERLERİNİN ÇERÇEVELEME ANALİZİ
Authors: YETKİNER Beyler , ÖZARSLAN Hüseyin , GÜRAN M. Salih
Published: September 2023

15 Ekim 2022 tarihinde, Bartın ilinin Amasra ilçesinde Türkiye Taşkömürü Kurumu (TTK) Amasra Müessese Müdürlüğü'ne bağlı kömür madeninde grizu patlaması oldu, sonrasında göçük ve yangın meydana geldi. Yaşanan maden kazasında yeraltında bulunan 110 madenciden 42’si hayatını kaybetti. Basında önce “kaza” “facia”, “patlama” kelimeleriyle kurulan haber öyküleri Cumhurbaşkanı Recep Tayyip Erdoğan’ın arama kurtarma faaliyetlerini incelemek üzere gittiği Bartın’da “Kader planına inandığımız için bunun ne dünü bugünü ne de yarını olmayacaktır bunlar her zaman olacaktır. Bunu da bilmemiz lazım.” şeklindeki açıklamasından sonra yön değiştirdi. Medya ve siyaset sahnesinde kader ve şehitlik tartışması başladı ve yeni bir kutuplaşma yaşandı. Kutuplaşmanın bir tarafında siyasi aktörlerin sponsorluğunda “şehit”, “kader” gibi kültür ve din referanslı çerçeveler diğer tarafta ise “ihmal/tedbirsizlik, cinayet/katliam” gibi sorumluluk atıflarının hakim olduğu çerçevelerle inşa edilmiş haberler ortaya çıktı.

Bu araştırma yaygın medyanın haber söylemini ve siyasi aktörlerin söylemlerini izleyerek çerçeveleme kuramının toplumsal-siyasi süreçlerin analizinde ne ölçüde pratik bir araç olduğunu anlamayı ve ayrıca Türk medyasında maden kazasıyla ilgili haberlerdeki çerçeveleme tercihlerini ortaya koymayı amaçlamaktadır. Çerçeveleme teorisi, siyasi aktörlerin ve medya aktörlerinin söylemlerinin, ortaya çıkış sürecinden başlayarak, birbirleriyle çatışmaları, izlerkitle çerçeveleriyle etkileşimleri, zaman içindeki dönüşümleri ve sosyal kültürel-politik arka planlarını da göz önünde bulundurularak analiz edilmesinde yararlı bir yöntem oluşturmaktadır. Bu bağlamda Birgün, Karar, Sabah, Sözcü, Yeni Akit, Yeni Şafak gazetelerinde Amasra Maden Kazasıyla ilgili yayımlanan toplam 276 haber çerçeve analizine tabi tutulmuştur. Araştırma sonucunda Sabah, Yeni Şafak ve Yeni Akit gazetelerinin “şehit”, “kader”, “devlet görev başında” çerçeveleriyle; Sözcü, Karar, Birgün gazetelerinin ise “cinayet/katliam”, “ihmal/tedbirsizlik”, “kader söylemine tepki” çerçeveleriyle kaza haberlerini çerçevelediği bulunmuştur. Gazetelerin en çok tercih ettiği tür çerçevesi ise insani ilgi çerçevesi olmuştur.
Selection and adaptation of teaching materials for content and language integrated learning
Authors: Baydikova Tatiana V. , Makarova Elena L.
Published: September 2023

Importance. Language teaching in higher education is aimed not only to promote the development of communicative competence at medium and high levels, but also to be a way of familiarizing students with specialized foreign language discourse. One of the most common methods that can accomplish these two tasks is Content and Language Integrated Learning. With its help, it is possible to adapt authentic materials to the requirements of linguodidactics. However, the question of the procedure for creating teaching materials for an integrated course remains open – there is a need to determine the general properties of selected and adapted texts for Content and Language Integrated Learning.
Research methods. The research is based on the scientific literature devoted to the organization of the integrated learning course. The connections between the systems of materials creation proposed by various authors were revealed via comparative analysis.
Results and Discussion. In the course of the study, a list of the properties of educational texts necessary for effective teaching of a professional foreign language was established. Different models of selection, ordering and adaptation of authentic texts are also considered. The correlation of the variety of properties and methods of organizing materials led to the creation of a three-module system that includes content, cognitive and communicative components. Each of the components operates with special characteristics of the selected and adapted texts: content – professional relevance of the texts; cognitive – the potential novelty of the perceived material; communicative – language and speech means to create communication environment.
Conclusion. The proposed three-module system of adaptation of authentic materials for Content and Language Integrated Learning is able to cover a variety of characteristics of texts, thereby providing opportunities for effective organization of the educational process.