bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S16 from Tumor Cell–Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer
Authors: Chen Hao , Cresswell Gregory M. , Libring Sarah , Ayers Mitchell G. , Miao Jinmin , Zhang Zhong-Yin , Solorio Luis , Ratliff Timothy L. , Wendt Michael K.
Published: April 2023

SHP2 regulates MHC class I expression via the balance between MAPK and STAT1 signaling in human MBC cells.
Supplementary Figure S15 from Tumor Cell–Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer
Authors: Chen Hao , Cresswell Gregory M. , Libring Sarah , Ayers Mitchell G. , Miao Jinmin , Zhang Zhong-Yin , Solorio Luis , Ratliff Timothy L. , Wendt Michael K.
Published: April 2023

Growth factors and 3D culture environment induce PD-L1 in MBC cells.
Supplementary Figure S13 from Tumor Cell–Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer
Authors: Chen Hao , Cresswell Gregory M. , Libring Sarah , Ayers Mitchell G. , Miao Jinmin , Zhang Zhong-Yin , Solorio Luis , Ratliff Timothy L. , Wendt Michael K.
Published: April 2023

Inhibition or depletion of SHP2 and PD-L1 blockade rescue T cell cytotoxicity.
Supplementary Table TS1 from Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non–small Cell Lung Cancer
Authors: Frank Malene S. , Andersen Christina S.A. , Ahlborn Lise B. , Pallisgaard Niels , Bodtger Uffe , Gehl Julie
Published: April 2023

Sequencing data of tumor tissue in each patient case
Supplementary Figure S11 from Tumor Cell–Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer
Authors: Chen Hao , Cresswell Gregory M. , Libring Sarah , Ayers Mitchell G. , Miao Jinmin , Zhang Zhong-Yin , Solorio Luis , Ratliff Timothy L. , Wendt Michael K.
Published: April 2023

Representative dot plots for data shown in figure 4G-H and additional myeloid composition analysis in mice bearing 4T1 metastases.
Supplementary Figure FS5 from Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non–small Cell Lung Cancer
Authors: Frank Malene S. , Andersen Christina S.A. , Ahlborn Lise B. , Pallisgaard Niels , Bodtger Uffe , Gehl Julie
Published: April 2023

OS and PFS – substantial/no substantial increase
Supplementary Figure FS4 from Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non–small Cell Lung Cancer
Authors: Frank Malene S. , Andersen Christina S.A. , Ahlborn Lise B. , Pallisgaard Niels , Bodtger Uffe , Gehl Julie
Published: April 2023

OS and PFS – cfDNA
Supplementary Table S1 from Avian Paramyxovirus 4 Antitumor Activity Leads to Complete Remissions and Long-term Protective Memory in Preclinical Melanoma and Colon Carcinoma Models
Authors: Javaheri Aryana , Bykov Yonina , Mena Ignacio , García-Sastre Adolfo , Cuadrado-Castano Sara
Published: April 2023

APMV-4 reverse genetics system primers
Supplementary Fig. S2 from Avian Paramyxovirus 4 Antitumor Activity Leads to Complete Remissions and Long-term Protective Memory in Preclinical Melanoma and Colon Carcinoma Models
Authors: Javaheri Aryana , Bykov Yonina , Mena Ignacio , García-Sastre Adolfo , Cuadrado-Castano Sara
Published: April 2023

Experimental inoculation of APMVs in mice
Table S1 and Table S2 from Distinct Predictive Immunogenomic Profiles of Response to Immune Checkpoint Inhibitors and IL2: A Real-world Evidence Study of Patients with Advanced Renal Cancer
Authors: Eisner Joel R. , Beebe Kirk D. , Mayhew Gregory M. , Shibata Yoichiro , Guo Yuelong , Farhangfar Carol , Farhangfar Farhang , Uronis Joshua M. , Mooney Jill , Milburn Michael V. , Foureau David , White Richard L. , Amin Asim , Milla Marcos E.
Published: April 2023

40 gene IL-2 response classifier and related immune cell types
Figure S7 from Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment
Authors: Kacher Jamila , Manches Olivier , Aspord Caroline , Sartelet Hervé , Chaperot Laurence
Published: April 2023

Supplementary figure 7 shows heat map and dot plots illustrating correlations between CD3E and chemokines levels, detailed migration of CD4 and CD8 lymphocytes driven by cell lines, correlations between CD3E and CD1c and between CCL19/CCL22 and APC specific markers.
Figure S3 from Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment
Authors: Kacher Jamila , Manches Olivier , Aspord Caroline , Sartelet Hervé , Chaperot Laurence
Published: April 2023

Supplementary figure 3 shows flow cytometry gating strategy and raw data in calcium mobilization experiments in all cell subsets
Figure S1 from Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment
Authors: Kacher Jamila , Manches Olivier , Aspord Caroline , Sartelet Hervé , Chaperot Laurence
Published: April 2023

Supplementary figure 1 shows chemokine arrays details: row data for culture medium, map of the array, and normalized data for all chemokines
Supplementary Figure S5 from A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis
Authors: Bora-Singhal Namrata , Saha Biswarup , Mohankumar Durairaj , Padmanabhan Jaya , Coppola Domenico , Chellappan Srikumar
Published: April 2023

High levels of YAP1-HIF1 alpha levels in mouse tumors
Supplementary Figure S4 from A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis
Authors: Bora-Singhal Namrata , Saha Biswarup , Mohankumar Durairaj , Padmanabhan Jaya , Coppola Domenico , Chellappan Srikumar
Published: April 2023

Hypoxia-induced reduction in YAP1-PHD2 co-localization
Supplementary Figure S2 from A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis
Authors: Bora-Singhal Namrata , Saha Biswarup , Mohankumar Durairaj , Padmanabhan Jaya , Coppola Domenico , Chellappan Srikumar
Published: April 2023

Single antibody controls for proximity ligation assays
Supplementary Figure S1 from A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis
Authors: Bora-Singhal Namrata , Saha Biswarup , Mohankumar Durairaj , Padmanabhan Jaya , Coppola Domenico , Chellappan Srikumar
Published: April 2023

Transient transfection data
Figure S9 from CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy
Authors: Cao Anthony , Yi Jiaqing , Tang Xinyan , Szeto Christopher W. , Wu Renyi , Wan Bing , Fang Xu , Li Shou , Wang Lei , Wang Lina , Li Jing , Ye Qiuping , Huang Tom , Hsu Karl , Kabbarah Omar , Zhou Haiying
Published: April 2023

M1/M2 modulation by ZL-1201
Supplementary Material S4 from Diagnostic Accuracy of Blood-based Biomarkers for Pancreatic Cancer: A Systematic Review and Meta-analysis
Authors: Kane Laura E. , Mellotte Gregory S. , Mylod Eimear , O'Brien Rebecca M. , O'Connell Fiona , Buckley Croí E. , Arlow Jennifer , Nguyen Khanh , Mockler David , Meade Aidan D. , Ryan Barbara M. , Maher Stephen G.
Published: April 2023

Inclusion exclusion criteria
Supplementary Material S3 from Diagnostic Accuracy of Blood-based Biomarkers for Pancreatic Cancer: A Systematic Review and Meta-analysis
Authors: Kane Laura E. , Mellotte Gregory S. , Mylod Eimear , O'Brien Rebecca M. , O'Connell Fiona , Buckley Croí E. , Arlow Jennifer , Nguyen Khanh , Mockler David , Meade Aidan D. , Ryan Barbara M. , Maher Stephen G.
Published: April 2023

Individualised search strategy
Supplementary Material S2 from Diagnostic Accuracy of Blood-based Biomarkers for Pancreatic Cancer: A Systematic Review and Meta-analysis
Authors: Kane Laura E. , Mellotte Gregory S. , Mylod Eimear , O'Brien Rebecca M. , O'Connell Fiona , Buckley Croí E. , Arlow Jennifer , Nguyen Khanh , Mockler David , Meade Aidan D. , Ryan Barbara M. , Maher Stephen G.
Published: April 2023

PRISMA flow chart
Supplementary Material S1 from Diagnostic Accuracy of Blood-based Biomarkers for Pancreatic Cancer: A Systematic Review and Meta-analysis
Authors: Kane Laura E. , Mellotte Gregory S. , Mylod Eimear , O'Brien Rebecca M. , O'Connell Fiona , Buckley Croí E. , Arlow Jennifer , Nguyen Khanh , Mockler David , Meade Aidan D. , Ryan Barbara M. , Maher Stephen G.
Published: April 2023

PRISMA 2020 checklist
Figure S6 from CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy
Authors: Cao Anthony , Yi Jiaqing , Tang Xinyan , Szeto Christopher W. , Wu Renyi , Wan Bing , Fang Xu , Li Shou , Wang Lei , Wang Lina , Li Jing , Ye Qiuping , Huang Tom , Hsu Karl , Kabbarah Omar , Zhou Haiying
Published: April 2023

Differentiation of macrophages
Figure S5 from CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy
Authors: Cao Anthony , Yi Jiaqing , Tang Xinyan , Szeto Christopher W. , Wu Renyi , Wan Bing , Fang Xu , Li Shou , Wang Lei , Wang Lina , Li Jing , Ye Qiuping , Huang Tom , Hsu Karl , Kabbarah Omar , Zhou Haiying
Published: April 2023

Macrophage content in TCGA
Tables S1-S4 from Cell-free DNA Predicts Prolonged Response to Multi-agent Chemotherapy in Pancreatic Ductal Adenocarcinoma
Authors: Christenson Eric S. , Lim Su Jin , Durham Jennifer , De Jesus-Acosta Ana , Bever Katherine , Laheru Daniel , Ryan Amy , Agarwal Parul , Scharpf Robert B. , Le Dung T. , Wang Hao
Published: April 2023

Table S1: Patient demographics. Table S2: Summary of TP53 VAF and KRAS VAF data for patient cohort (N=12). Table S3: Correlation between TP53 VAF, KRAS VAF, or median VAF and CEA and CA19-9 biomarkers using Spearman rank correlation coefficient (R). Table S4: Comparing predictive value of TP53 VAF, KRAS VAF, or median VAF versus CEA and CA19-9 for OS using C-index
Figure S4 from CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy
Authors: Cao Anthony , Yi Jiaqing , Tang Xinyan , Szeto Christopher W. , Wu Renyi , Wan Bing , Fang Xu , Li Shou , Wang Lei , Wang Lina , Li Jing , Ye Qiuping , Huang Tom , Hsu Karl , Kabbarah Omar , Zhou Haiying
Published: April 2023

Fc-dependent synergy of ZL-1201
Figure S3 from CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy
Authors: Cao Anthony , Yi Jiaqing , Tang Xinyan , Szeto Christopher W. , Wu Renyi , Wan Bing , Fang Xu , Li Shou , Wang Lei , Wang Lina , Li Jing , Ye Qiuping , Huang Tom , Hsu Karl , Kabbarah Omar , Zhou Haiying
Published: April 2023

In vitro phagocytosis by ZL-1201
Figure S1 from CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy
Authors: Cao Anthony , Yi Jiaqing , Tang Xinyan , Szeto Christopher W. , Wu Renyi , Wan Bing , Fang Xu , Li Shou , Wang Lei , Wang Lina , Li Jing , Ye Qiuping , Huang Tom , Hsu Karl , Kabbarah Omar , Zhou Haiying
Published: April 2023

ZL-1201 binding to CD47
Supplementary Table S8 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Summary of antibodies used in flow cytometry analyses.
Figure FS4 from Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
Authors: Widmer Carmen A. , Klebic Ismar , Domanitskaya Natalya , Decollogny Morgane , Howald Denise , Siffert Myriam , Essers Paul , Nowicka Zuzanna , Stokar-Regenscheit Nadine , van de Ven Marieke , de Korte-Grimmerink Renske , Galván José A. , Pritchard Colin E.J. , Huijbers Ivo J. , Fendler Wojciech , Vens Conchita , Rottenberg Sven
Published: April 2023

TIDE analysis and tumor growth curves of Kaplan Meyer survival graphs shown in main Figure 3
Supplementary Table S6. from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Predicted neoantigen candidates with strong binding (%Rank < 0.5).
Supplementary Table S2 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

NSCLC patient characteristics.
Supplementary Figure S6 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Additional in vivo data using MC-38 cells.
Supplementary Figure S4 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Additional in vitro data using the MC-38 clones.
Supplementary Figure S1 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Authors: Morinaga Takao , Inozume Takashi , Kawazu Masahito , Ueda Youki , Sax Nicolas , Yamashita Kazuo , Kawashima Shusuke , Nagasaki Joji , Ueno Toshihide , Lin Jason , Ohara Yuuki , Kuwata Takeshi , Yukami Hiroki , Kawazoe Akihito , Shitara Kohei , Honobe-Tabuchi Akiko , Ohnuma Takehiro , Kawamura Tatsuyoshi , Umeda Yoshiyasu , Kawahara Yu , Nakamura Yasuhiro , Kiniwa Yukiko , Morita Ayako , Ichihara Eiki , Kiura Katsuyuki , Enokida Tomohiro , Tahara Makoto , Hasegawa Yoshinori , Mano Hiroyuki , Suzuki Yutaka , Nishikawa Hiroyoshi , Togashi Yosuke
Published: April 2023

Clinical course of a gastric cancer patient, IHC, and sequencing data.
Supplementary Data S1 from Ad hoc Analysis of the Phase III ENGOT-OV16/NOVA Study: Niraparib Efficacy in Germline BRCA Wild-type Recurrent Ovarian Cancer with Homologous Recombination Repair Defects
Authors: Mirza Mansoor Raza , Lindahl Gabriel , Mahner Sven , Redondo Andrés , Fabbro Michel , Rimel Bobbie J. , Herrstedt Jørn , Oza Amit M. , Canzler Ulrich , Berek Jonathan S. , González-Martín Antonio , Follana Phillipe , Lord Rosemary , Azodi Masoud , Estenson Kasey , Wang Zebin , Li Yong , Gupta Divya , Matulonis Ursula , Feng Bin
Published: April 2023

Supplementary Data
Supplementary Figure 7 from Remodeling of the Tumor Microenvironment Through PAK4 Inhibition Sensitizes Tumors to Immune Checkpoint Blockade
Authors: Abril-Rodriguez Gabriel , Torrejon Davis Y. , Karin Daniel , Campbell Katie M. , Medina Egmidio , Saco Justin D. , Galvez Mildred , Champhekar Ameya S. , Perez-Garcilazo Ivan , Baselga-Carretero Ignacio , Singh Jas , Comin-Anduix Begoña , Puig-Saus Cristina , Ribas Antoni
Published: April 2023

Supplementary Figure 7: PAK4 protein expression levels in the different cell lines.
Table ST1 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Table S1 shows summary of all adverse events
Figure S9 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Figure S9 shows emotional well-being over time
Figure S8 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Figure S8 shows social/family well-being over time by response
Figure S6 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Figure S6 shows physical well-being over time by response
Figure S5 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Figure S5 shows physical wellbeing over time
Figure S2 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Figure S2 shows summary of normalized serum levels of cytokins/chemokines/growth factors at week 4
Figure S11 from Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Authors: Paller Channing J. , Wang Lin , Fu Wei , Kumar Rajendra , Durham Jennifer N. , Azad Nilofer S. , Laheru Daniel A. , Browner Ilene , Kachhap Sushant K. , Boyapati Kavya , Odeny Thomas , Armstrong Deborah K. , Meyer Christian F. , Gaillard Stephanie , Brahmer Julie R. , Page Ivelisse , Wang Hao , Diaz Luis A.
Published: April 2023

Figure S11 shows functional well-being over time by response
Supplementary Table ST1 from MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
Authors: Fukasawa Kazuya , Lyu Jiajun , Kubo Takuya , Tanaka Yuki , Suzuki Akane , Horie Tetsuhiro , Tomizawa Akane , Osumi Ryoma , Iwahashi Sayuki , Tokumura Kazuya , Murata Misato , Kobayashi Masaki , Todo Tomoki , Hirao Atsushi , Hinoi Eiichi
Published: April 2023

Supplementary Table
Figure S7 from MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
Authors: Fukasawa Kazuya , Lyu Jiajun , Kubo Takuya , Tanaka Yuki , Suzuki Akane , Horie Tetsuhiro , Tomizawa Akane , Osumi Ryoma , Iwahashi Sayuki , Tokumura Kazuya , Murata Misato , Kobayashi Masaki , Todo Tomoki , Hirao Atsushi , Hinoi Eiichi
Published: April 2023

Figure S7
Figure S5 from MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
Authors: Fukasawa Kazuya , Lyu Jiajun , Kubo Takuya , Tanaka Yuki , Suzuki Akane , Horie Tetsuhiro , Tomizawa Akane , Osumi Ryoma , Iwahashi Sayuki , Tokumura Kazuya , Murata Misato , Kobayashi Masaki , Todo Tomoki , Hirao Atsushi , Hinoi Eiichi
Published: April 2023

Figure S5
Supplementary Figure SF3 from Antibody Binding and Neutralization of Live SARS-CoV-2 Variants Including BA.4/5 Following Booster Vaccination of Patients with B-cell Malignancies
Authors: Chang Andres , Akhtar Akil , Lai Lilin , Orellana-Noia Victor M. , Linderman Susanne L. , McCook-Veal Ashley A. , Switchenko Jeffrey M. , Saini Manpreet , Valanparambil Rajesh M. , Blum Kristie A. , Allen Pamela B. , Lechowicz Mary Jo , Romancik Jason T. , Ayers Amy , Leal Alyssa , O'Leary Colin B. , Churnetski Michael C. , Baird Katelin , Kives Melissa , Wrammert Jens , Nooka Ajay K. , Koff Jean L. , Dhodapkar Madhav V. , Suthar Mehul S. , Cohen Jonathon B. , Ahmed Rafi
Published: April 2023

Supplemental Figure 3. Kinetics of serologic response after booster vaccination.
Figure S4 from MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
Authors: Fukasawa Kazuya , Lyu Jiajun , Kubo Takuya , Tanaka Yuki , Suzuki Akane , Horie Tetsuhiro , Tomizawa Akane , Osumi Ryoma , Iwahashi Sayuki , Tokumura Kazuya , Murata Misato , Kobayashi Masaki , Todo Tomoki , Hirao Atsushi , Hinoi Eiichi
Published: April 2023

Figure S4
Supplementary Figure SF1 from Antibody Binding and Neutralization of Live SARS-CoV-2 Variants Including BA.4/5 Following Booster Vaccination of Patients with B-cell Malignancies
Authors: Chang Andres , Akhtar Akil , Lai Lilin , Orellana-Noia Victor M. , Linderman Susanne L. , McCook-Veal Ashley A. , Switchenko Jeffrey M. , Saini Manpreet , Valanparambil Rajesh M. , Blum Kristie A. , Allen Pamela B. , Lechowicz Mary Jo , Romancik Jason T. , Ayers Amy , Leal Alyssa , O'Leary Colin B. , Churnetski Michael C. , Baird Katelin , Kives Melissa , Wrammert Jens , Nooka Ajay K. , Koff Jean L. , Dhodapkar Madhav V. , Suthar Mehul S. , Cohen Jonathon B. , Ahmed Rafi
Published: April 2023

Supplemental Figure 1. Anti-nucleocapsid IgG and spike IgM titers in NHL/CLL patients.
Supplementary Figure S5 from Complex Patterns of Genomic Heterogeneity Identified in 42 Tumor Samples and ctDNA of a Pulmonary Atypical Carcinoid Patient
Authors: Robb Tamsin J. , Tsai Peter , Fitzgerald Sandra , Shields Paula , Houseman Pascalene S. , Patel Rachna , Fan Vicky , Curran Ben , Tse Rexson , Ting Jacklyn , Kramer Nicole , Woodhouse Braden J. , Coats Esther , Le Quesne Stabej Polona , Reeve Jane , Parker Kate , Lawrence Ben , Blenkiron Cherie , Print Cristin G.
Published: April 2023

Supplementary Figure S5: Inference of putative sequences of genomic changes consistent with
the data using the LICHeE and REVOLVER methods LICHeE and Revolver were used to further speculate the order of genomic changes in this patient's dataset. ClonEvol was also trialed, using PyClone putative clonal clusters as input, however the results did not converge. A, LICHeE was run according to the tool creator's instructions, using VAFs as input, to generate clonal relationships of tumor samples. Numbers inside colored circles represent the number of mutations defining a clone, and the squares represent the clonal structures of individual samples.
Shaded regions indicate the proportion of cells belonging to that clone, where the white regions
represent normal cells. Four dominant tumor groups were apparent. Where two or more colors are
present, LICHeE has predicted the sample to contain a mixture of clones (most apparent in Pa1 and Lu1
but also present in In2, Pa6 and others). This feature is also visible in the VAF plot (Figure 5a) but not
represented on the DNA phylogram (Figure 5b). Technical reasons prevented the inclusion of some
samples, e.g. Lu8 and Pa5. B, Clonal relationships between tumor samples as predicted by REVOLVER,
using PyClone putative clonal clusters as input (from VAF and chromosomal copy number), and default
tool parameters. Clones are labeled according to one variant defining that clone (e.g., MASTL), and the
circle size is proportional to the number of variants defining the clone. Number refers to clone number.
REVOLVER highlighted the same pattern of progression seen in other analyses: from normal cells,
common variants accumulate (labeled as MASTL in Figure 5b), and a further set of variants shared by
most tumors was identified (labeled GPAM) before a split into two dominant tumor groups, each
characterized by their own set of variants (labeled SLIT1 and PAQR6 respectively). REVOLVER highlights
the progression of variant accumulation across all samples, rather than indicating individual samples.
All coloring consistent with Figure 5. Overall, LICHeE and REVOLVER explore the clonal and subclonal
structure of individual tumor samples and suggest the same sequence of genomic progression evident
in the DNA phylogram (Figure 5b). None of these cancer-specific methods attempts to time the
evolutionary divergence events.
Supplementary Figure S3 from Complex Patterns of Genomic Heterogeneity Identified in 42 Tumor Samples and ctDNA of a Pulmonary Atypical Carcinoid Patient
Authors: Robb Tamsin J. , Tsai Peter , Fitzgerald Sandra , Shields Paula , Houseman Pascalene S. , Patel Rachna , Fan Vicky , Curran Ben , Tse Rexson , Ting Jacklyn , Kramer Nicole , Woodhouse Braden J. , Coats Esther , Le Quesne Stabej Polona , Reeve Jane , Parker Kate , Lawrence Ben , Blenkiron Cherie , Print Cristin G.
Published: April 2023

Supplementary Figure S3: Mutational signatures across all samples collected at autopsy
A, Overall mutational burden does not reveal significant mutational signatures (MuSiCa). The signature
contribution is indicated by the degree of shading (key to right). The signature with the highest
contribution was Signature 3, however it was not statistically significant in most samples according to
tool Signal. B, The scarHRD method for quantifying homologous recombination deficiency did not
identify any tumors to be HR-deficient; with all having an HRD-sum score < 20 (known HR-deficient
tumors usually have HRD-sums of > 40)28.
Supplementary Figure S1 from Complex Patterns of Genomic Heterogeneity Identified in 42 Tumor Samples and ctDNA of a Pulmonary Atypical Carcinoid Patient
Authors: Robb Tamsin J. , Tsai Peter , Fitzgerald Sandra , Shields Paula , Houseman Pascalene S. , Patel Rachna , Fan Vicky , Curran Ben , Tse Rexson , Ting Jacklyn , Kramer Nicole , Woodhouse Braden J. , Coats Esther , Le Quesne Stabej Polona , Reeve Jane , Parker Kate , Lawrence Ben , Blenkiron Cherie , Print Cristin G.
Published: April 2023

Supplementary Figure S1: ADTEx copy number analysis of Biopsy 1 from low coverage WES
Copy number profile of low-coverage WES of Biopsy 1 revealing A, likely amplification of Chr 5 and B,
loss of Chr 21. Top panels display DOC ratio, colored by predicted copy number state. Bottom panels
display BAF, colored by predicted copy number alteration. The separation of BAF towards 0.3 and 0.6 in
Chr 5 indicates chromosomal gain, whereas the separation of BAF towards 0 and 1 in Chr 21 indicates
LoH. There was insufficient evidence conclusively identify the presence or absence of the loss of C, Chr
6 and D, chromothripsis of one copy of Chr 11 based on ADTEx analysis of the low-coverage WES of
Biopsy 1, however it is likely that they were absent. Copy number analysis was plagued with high levels
of noise from low coverage and large differences in coverage between the Biopsy 1 and normal sample.
The sole Chr 11 breakpoint covered by the exome sequencing did not provide read support for
chromothripsis. The apparent amplifications of regions of each chromosome do not match up to any
known alterations in high-quality DNA samples from tumours collected at autopsy and are likely
attributable to noise in the low coverage WES.
Table S2 from Mouse Stromal Cells Confound Proteomic Characterization and Quantification of Xenograft Models
Authors: Shi Zhaomei , Mao Binchen , Chen Xiaobo , Hao Piliang , Guo Sheng
Published: April 2023

Gene set enrichment analysis results using the top 1000 DEPs between the original and de-moused tumors for each of five PDX models.
Supplemental Figures S1-S6 from Grain, Gluten, and Dietary Fiber Intake Influence Gut Microbial Diversity: Data from the Food and Microbiome Longitudinal Investigation
Authors: Um Caroline Y. , Peters Brandilyn A. , Choi Hee Sun , Oberstein Paul , Beggs Dia B. , Usyk Mykhaylo , Wu Feng , Hayes Richard B. , Gapstur Susan M. , McCullough Marjorie L. , Ahn Jiyoung
Published: April 2023

S1. Gut microbiome alpha- and beta-diversity according to energy-adjusted quartiles of dietary fiber intake in the Food and Microbiome Longitudinal Investigation (FAMiLI).

S2. Gut microbiome alpha- and beta-diversity according to energy-adjusted quartiles of whole grain intake in the Food and Microbiome Longitudinal Investigation (FAMiLI), stratified by race/ethnicity.

S3. Gut microbiome alpha- and beta-diversity according to energy-adjusted quartiles of whole grain intake in the Food and Microbiome Longitudinal Investigation (FAMiLI).

S4. Gut microbiome alpha- and beta-diversity according to energy-adjusted quartiles of whole grain intake in the Food and Microbiome Longitudinal Investigation (FAMiLI), excluding participants with self-reported inflammatory bowel disease (N=21) at enrollment.

S5. Gut microbiome alpha- and beta-diversity according to energy-adjusted quartiles of refined grain (with sweets/desserts) intake in the Food and Microbiome Longitudinal Investigation (FAMiLI).

S6. Gut microbiome alpha- and beta-diversity according to energy-adjusted quartiles of gluten (with sweets/desserts) intake in the Food and Microbiome Longitudinal Investigation (FAMiLI).
Table S1 from Mouse Stromal Cells Confound Proteomic Characterization and Quantification of Xenograft Models
Authors: Shi Zhaomei , Mao Binchen , Chen Xiaobo , Hao Piliang , Guo Sheng
Published: April 2023

Protein quantification results in cell line mixtures and PDX tumors.
Table TS2 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Authors: Tucker John B. , Bonema Sarah C. , García-Varela Rebeca , Denu Ryan A. , Hu Yang , McGregor Stephanie M. , Burkard Mark E. , Weaver Beth A.
Published: April 2023

Table S2. Patient characteristics of matched primary and metastatic cases
Table TS1 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Authors: Tucker John B. , Bonema Sarah C. , García-Varela Rebeca , Denu Ryan A. , Hu Yang , McGregor Stephanie M. , Burkard Mark E. , Weaver Beth A.
Published: April 2023

Table S1. Patient characteristics
Movie S4 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Authors: Tucker John B. , Bonema Sarah C. , García-Varela Rebeca , Denu Ryan A. , Hu Yang , McGregor Stephanie M. , Burkard Mark E. , Weaver Beth A.
Published: April 2023

Chromosome bridge
Movie S2 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Authors: Tucker John B. , Bonema Sarah C. , García-Varela Rebeca , Denu Ryan A. , Hu Yang , McGregor Stephanie M. , Burkard Mark E. , Weaver Beth A.
Published: April 2023

Misaligned chromosome that persists through anaphase onset
Movie S1 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Authors: Tucker John B. , Bonema Sarah C. , García-Varela Rebeca , Denu Ryan A. , Hu Yang , McGregor Stephanie M. , Burkard Mark E. , Weaver Beth A.
Published: April 2023

Normal division
Fig FS5 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Authors: Tucker John B. , Bonema Sarah C. , García-Varela Rebeca , Denu Ryan A. , Hu Yang , McGregor Stephanie M. , Burkard Mark E. , Weaver Beth A.
Published: April 2023

Figure S5. Chromosomes that are misaligned at anaphase onset are rapidly incorporated
into the main DNA masses during anaphase A. A-B. Timelapse analysis of T47D (A) and
Cal51 (B) breast cancer cells with endogenously labeled histone H2B and a-tubulin showing the
fate of misaligned chromosomes after anaphase entry. In cells that entered anaphase with
misaligned chromosomes, the majority of the misaligned chromosomes reincorporated into the
main masses of segregating DNA during anaphase A (left columns). A smaller portion of
misaligned chromosomes remained distinct from the segregating DNA masses and therefore
visible throughout anaphase A (middle column). A small minority of misaligned chromosomes
were detectable for at least 2 minutes during anaphase B (right column). n>25 cells with
misaligned chromosomes in 3 biological replicates. C-D timing of anaphase and telophase in
T47D (C) and Cal51 (D) cells. n>55 cells in 3 biological replicates.
Fig FS3 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Authors: Tucker John B. , Bonema Sarah C. , García-Varela Rebeca , Denu Ryan A. , Hu Yang , McGregor Stephanie M. , Burkard Mark E. , Weaver Beth A.
Published: April 2023

Figure S3. Lagging chromosomes in breast cancer are primarily mitotic in origin. A-B.
Images of lagging chromosomes lacking a centromere, which are likely to occur due to premitotic
defects (A) or containing their centromere, which are likely to arise due to mitotic defects
(B). C. Quantification of lagging chromosomes in 8 primary tumors showing acentric (ACA-)
fragments are less frequent than lagging chromosomes containing centromeres. Data represent
mean +/- SD.
Fig FS2 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Authors: Tucker John B. , Bonema Sarah C. , García-Varela Rebeca , Denu Ryan A. , Hu Yang , McGregor Stephanie M. , Burkard Mark E. , Weaver Beth A.
Published: April 2023

Figure S2. Breast tumor subtypes show similar rates of mitotic defects. A. Triple Negative
(TN) and HER2+ tumors show higher CIN as assessed by 6-chromosome interphase FISH (see
Methods) than hormone (ER and/or PR) receptor positive (HR+) tumors. n = 235, 45, 46
respectively. B. Rates of mitotic defects are similar in all subtypes.
Fig FS1 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Authors: Tucker John B. , Bonema Sarah C. , García-Varela Rebeca , Denu Ryan A. , Hu Yang , McGregor Stephanie M. , Burkard Mark E. , Weaver Beth A.
Published: April 2023

Figure S1. Pipeline to assess CIN in primary breast cancer. A. A tissue microarray
containing 377 breast cancer and 17 normal breast samples was evaluated for proliferation by
Ki67 and CIN based on 6 chromosome FISH (39). H&E stained sections for cases with sufficient
proliferation to assess mitotic cells with a range of CIN scores were analyzed for mitotic defects.
Linear correlations were used to compare CIN by FISH to mitotic defects in tumor sections.
Table TS5 from Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma
Authors: Wong Derek , Luo Ping , Znassi Nadia , Arteaga Diana P. , Gray Diana , Danesh Arnavaz , Han Ming , Zhao Eric Y. , Pedersen Stephanie , Prokopec Stephenie , Sundaravadanam Yogi , Torti Dax , Marsh Kayla , Keshavarzi Sareh , Xu Wei , Krema Hatem , Joshua Anthony M. , Butler Marcus O. , Pugh Trevor J.
Published: April 2023

differentially methylated probes
Supplementary Data SD1 from A Miniaturized Screening Platform to Identify Novel Regulators of Extracellular Matrix Alignment
Authors: Jones Caitlin E. , Sharick Joe T. , Sizemore Steven T. , Cukierman Edna , Strohecker Anne Marie , Leight Jennifer L.
Published: April 2023

Figure S1, S2, S3, Table S1 and S2
Table TS1 from Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma
Authors: Wong Derek , Luo Ping , Znassi Nadia , Arteaga Diana P. , Gray Diana , Danesh Arnavaz , Han Ming , Zhao Eric Y. , Pedersen Stephanie , Prokopec Stephenie , Sundaravadanam Yogi , Torti Dax , Marsh Kayla , Keshavarzi Sareh , Xu Wei , Krema Hatem , Joshua Anthony M. , Butler Marcus O. , Pugh Trevor J.
Published: April 2023

panel design
Figure S4 from Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma
Authors: Wong Derek , Luo Ping , Znassi Nadia , Arteaga Diana P. , Gray Diana , Danesh Arnavaz , Han Ming , Zhao Eric Y. , Pedersen Stephanie , Prokopec Stephenie , Sundaravadanam Yogi , Torti Dax , Marsh Kayla , Keshavarzi Sareh , Xu Wei , Krema Hatem , Joshua Anthony M. , Butler Marcus O. , Pugh Trevor J.
Published: April 2023

Supplemental Figure 4
Figure S3 from Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma
Authors: Wong Derek , Luo Ping , Znassi Nadia , Arteaga Diana P. , Gray Diana , Danesh Arnavaz , Han Ming , Zhao Eric Y. , Pedersen Stephanie , Prokopec Stephenie , Sundaravadanam Yogi , Torti Dax , Marsh Kayla , Keshavarzi Sareh , Xu Wei , Krema Hatem , Joshua Anthony M. , Butler Marcus O. , Pugh Trevor J.
Published: April 2023

Supplemental Figure 3
Figure S1 from Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma
Authors: Wong Derek , Luo Ping , Znassi Nadia , Arteaga Diana P. , Gray Diana , Danesh Arnavaz , Han Ming , Zhao Eric Y. , Pedersen Stephanie , Prokopec Stephenie , Sundaravadanam Yogi , Torti Dax , Marsh Kayla , Keshavarzi Sareh , Xu Wei , Krema Hatem , Joshua Anthony M. , Butler Marcus O. , Pugh Trevor J.
Published: April 2023

Supplemental Figure 1
Supplementary File S1 from A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
Authors: Nygaard Vigdis , Ree Anne Hansen , Dagenborg Vegar Johansen , Børresen-Dale Anne-Lise , Edwin Bjørn , Fretland Åsmund Avdem , Grzyb Krzysztof , Haugen Mads H. , Mælandsmo Gunhild M. , Flatmark Kjersti
Published: April 2023

Supplementary File S1 Data S1-S9
Supplementary Figure 2 from Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis
Authors: Benwell Christopher J. , Johnson Robert T. , Taylor James A.G.E. , Price Christopher A. , Robinson Stephen D.
Published: April 2023

Angiogenesis is inhibited in PyMT-BO1 tumours upon NRP1 and NRP2 depletion
Supplementary Figure 1 from Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis
Authors: Benwell Christopher J. , Johnson Robert T. , Taylor James A.G.E. , Price Christopher A. , Robinson Stephen D.
Published: April 2023

Co-targeting NRP1 and NRP2 inhibits tumour growth and angiogenesis
Table S1 from Loss of Dok-3 in Non-tumor Cells Induces Malignant Transformation of Benign Epithelial Tumor Cells of the Intestine
Authors: Arimura Sumimasa , Inoue-Yamauchi Akane , Katayama Kotoe , Kanno Tatsuo , Jozawa Hiroki , Imoto Seiya , Yamanashi Yuji
Published: April 2023

95 genes significantly mutated in human colorectal cancer.
Suppl. Fig. S8 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42
Authors: Medina Julia I. , Cruz-Collazo Ailed , Maldonado Maria del Mar , Matos Gascot Tatiana , Borrero-Garcia Luis D. , Cooke Mariana , Kazanietz Marcelo G. , Hernandez O'Farril Eliud , Vlaar Cornelis P. , Dharmawardhane Suranganie
Published: April 2023

Supplementary Figure S8 shows nucleotide loading of GTP binding to Rho GTPases.
Suppl. Fig. S7 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42
Authors: Medina Julia I. , Cruz-Collazo Ailed , Maldonado Maria del Mar , Matos Gascot Tatiana , Borrero-Garcia Luis D. , Cooke Mariana , Kazanietz Marcelo G. , Hernandez O'Farril Eliud , Vlaar Cornelis P. , Dharmawardhane Suranganie
Published: April 2023

Supplementary Figure S7 shows the effect of MBQ-167 on Rac1(G15A) association with Tiam-1 and p-REX-1.
Suppl. Fig. S6 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42
Authors: Medina Julia I. , Cruz-Collazo Ailed , Maldonado Maria del Mar , Matos Gascot Tatiana , Borrero-Garcia Luis D. , Cooke Mariana , Kazanietz Marcelo G. , Hernandez O'Farril Eliud , Vlaar Cornelis P. , Dharmawardhane Suranganie
Published: April 2023

Supplementary Figure S6 shows the inhibition of Rac1B, Rac1, and Rac1 P29S by MBQ-167
Suppl. Fig. S5 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42
Authors: Medina Julia I. , Cruz-Collazo Ailed , Maldonado Maria del Mar , Matos Gascot Tatiana , Borrero-Garcia Luis D. , Cooke Mariana , Kazanietz Marcelo G. , Hernandez O'Farril Eliud , Vlaar Cornelis P. , Dharmawardhane Suranganie
Published: April 2023

Supplementary Figure S5 shows the effect of MBQ compounds on Rac activation in attached and detached cells.
Figure S4 from Loss of Dok-3 in Non-tumor Cells Induces Malignant Transformation of Benign Epithelial Tumor Cells of the Intestine
Authors: Arimura Sumimasa , Inoue-Yamauchi Akane , Katayama Kotoe , Kanno Tatsuo , Jozawa Hiroki , Imoto Seiya , Yamanashi Yuji
Published: April 2023

Stromal reaction associated with invasive tumors of Apc/Dok3 mice.
Suppl. Fig. S4 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42
Authors: Medina Julia I. , Cruz-Collazo Ailed , Maldonado Maria del Mar , Matos Gascot Tatiana , Borrero-Garcia Luis D. , Cooke Mariana , Kazanietz Marcelo G. , Hernandez O'Farril Eliud , Vlaar Cornelis P. , Dharmawardhane Suranganie
Published: April 2023

Supplementary Figure S4 shows the safety of MBQ compounds in mice.
Figure S2 from Loss of Dok-3 in Non-tumor Cells Induces Malignant Transformation of Benign Epithelial Tumor Cells of the Intestine
Authors: Arimura Sumimasa , Inoue-Yamauchi Akane , Katayama Kotoe , Kanno Tatsuo , Jozawa Hiroki , Imoto Seiya , Yamanashi Yuji
Published: April 2023

Loss of Dok-1/-2 has no significant effect on invasiveness of tumors in Apc mice.
Suppl. Fig. S3 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42
Authors: Medina Julia I. , Cruz-Collazo Ailed , Maldonado Maria del Mar , Matos Gascot Tatiana , Borrero-Garcia Luis D. , Cooke Mariana , Kazanietz Marcelo G. , Hernandez O'Farril Eliud , Vlaar Cornelis P. , Dharmawardhane Suranganie
Published: April 2023

Suppl. Fig. S3 shows the effect of MBQ-167 and derivatives on lung cancer cells.
Suppl. Fig. S2 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42
Authors: Medina Julia I. , Cruz-Collazo Ailed , Maldonado Maria del Mar , Matos Gascot Tatiana , Borrero-Garcia Luis D. , Cooke Mariana , Kazanietz Marcelo G. , Hernandez O'Farril Eliud , Vlaar Cornelis P. , Dharmawardhane Suranganie
Published: April 2023

Supplemental Figure S2 shows the Effect of MBQ compounds on cell migration
Suppl. Fig. S1 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42
Authors: Medina Julia I. , Cruz-Collazo Ailed , Maldonado Maria del Mar , Matos Gascot Tatiana , Borrero-Garcia Luis D. , Cooke Mariana , Kazanietz Marcelo G. , Hernandez O'Farril Eliud , Vlaar Cornelis P. , Dharmawardhane Suranganie
Published: April 2023

Suppl. Fig. S1 shows percentage cell viability
Figure S5 from Targeting MLL Methyltransferases Enhances the Antitumor Effects of PI3K Inhibition in Hormone Receptor–positive Breast Cancer
Authors: Jones Robert B. , Farhi Jonathan , Adams Miranda , Parwani Kiran K. , Cooper Garrett W. , Zecevic Milica , Lee Richard S. , Hong Andrew L. , Spangle Jennifer M.
Published: April 2023

Figure S5 shows that combined PI3K and MLL inhibition provides therapeutic benefit in vitro and in vivo
Figure S3 from Targeting MLL Methyltransferases Enhances the Antitumor Effects of PI3K Inhibition in Hormone Receptor–positive Breast Cancer
Authors: Jones Robert B. , Farhi Jonathan , Adams Miranda , Parwani Kiran K. , Cooper Garrett W. , Zecevic Milica , Lee Richard S. , Hong Andrew L. , Spangle Jennifer M.
Published: April 2023

Figure S3 shows additional transcriptional and genomics analyses that support MLL1 inhibitor-driven hyperactivation of AKT
Figure S2 from Targeting MLL Methyltransferases Enhances the Antitumor Effects of PI3K Inhibition in Hormone Receptor–positive Breast Cancer
Authors: Jones Robert B. , Farhi Jonathan , Adams Miranda , Parwani Kiran K. , Cooper Garrett W. , Zecevic Milica , Lee Richard S. , Hong Andrew L. , Spangle Jennifer M.
Published: April 2023

Figure S2 shows on-target activity of PI3K and MLL1 inhibitors
Supplementary Movie 1 from Three-dimensional Imaging Reveals Immune-driven Tumor-associated High Endothelial Venules as a Key Correlate of Tumor Rejection Following Depletion of Regulatory T Cells
Authors: Milutinovic Stefan , Abe Jun , Jones Emma , Kelch Inken , Smart Kathryn , Lauder Sarah N. , Somerville Michelle , Ware Carl , Godkin Andrew , Stein Jens V. , Bogle Gib , Gallimore Awen
Published: April 2023

Global overview of intra-tumoral HEVs in a 4T1 regressor tumour following PI-3065 treatment.
Figure S2 from Elevated Dietary Carbohydrate and Glycemic Intake Associate with an Altered Oral Microbial Ecosystem in Two Large U.S. Cohorts
Authors: Monson Kelsey R. , Peters Brandilyn A. , Usyk Mykhaylo , Um Caroline Y. , Oberstein Paul E. , McCullough Marjorie L. , Purdue Mark P. , Freedman Neal D. , Hayes Richard B. , Ahn Jiyoung
Published: April 2023

Carbohydrate and GI Pearson correlation
Figure S1 from Elevated Dietary Carbohydrate and Glycemic Intake Associate with an Altered Oral Microbial Ecosystem in Two Large U.S. Cohorts
Authors: Monson Kelsey R. , Peters Brandilyn A. , Usyk Mykhaylo , Um Caroline Y. , Oberstein Paul E. , McCullough Marjorie L. , Purdue Mark P. , Freedman Neal D. , Hayes Richard B. , Ahn Jiyoung
Published: April 2023

Population flow diagram
Figure S4 from Three-dimensional Imaging Reveals Immune-driven Tumor-associated High Endothelial Venules as a Key Correlate of Tumor Rejection Following Depletion of Regulatory T Cells
Authors: Milutinovic Stefan , Abe Jun , Jones Emma , Kelch Inken , Smart Kathryn , Lauder Sarah N. , Somerville Michelle , Ware Carl , Godkin Andrew , Stein Jens V. , Bogle Gib , Gallimore Awen
Published: April 2023

LSFM imaging of Treg depleted fibrosarcomas.