bluuebunny/crossref_metadata_2025 huggingface dataset:
Penentuan Kesalahan Korporasi Pada Tindak Pidana Perpajakan (Studi Putusan Pengadilan Negeri Jakarta Barat No.: 334/Pid.Sus/2020/PN Jkt.Brt)
Authors: Putra I Made Walesa , Marcus Priyo Gunarto  , Dahliana Hasan
Published: July 2022

AbstractThe Indonesian Criminal Code does not recognize corporate criminal liability. Conceptually, the perpetrator, who commits a criminal act must have a fault to be liable, including corporation as the subject of criminal law. The criminal sanctions impostion of PT. Gemilang Sukses Garmindo (PT. GSG) based on West Jakarta District Court through the decision number: 334/Pid.Sus/2020/PN Jkt.Brt, it was the second criminal decision against the corporation in the taxation sector, after the Asian Agri Group (AAG) decision. This study aims to analyze the regulation of corporate criminal liability in tax laws and to analyze the basis of judge considerations in determining the corporate guilt of PT GSG. The type of research is normative research with a statutory and case approach. The results of study showed that the Tax Law has not explicitly regulated the corporation as the subject of tax criminal law and there was an inaccuracy in the judge’s consideration of the PT.GSG criminal decision. The determination of corporate fault can be based on the material perpetrator’s fault and the internal requirements of the corporation. Finally, identification theory can be used as the basis for justifying the imposition of a corporate criminal sanction to PT. GSG.Keywords: Corporate Fault; Criminal Act; Taxation.
AbstrakKitab Undang-Undang Hukum Pidana (KUHP) Indonesia belum mengakui pertanggungjawaban pidana korporasi. Secara konsepsi, untuk dapat dipertanggungjawabkan pidana pelaku yang melakukan tindak pidana harus memiliki kesalahan, termasuk pula subjek hukum pidana korporasi. Pengenaan pidana terhadap PT. Gemilang Sukses Garmindo (PT. GSG) berdasarkan Putusan Pengadilan Negeri Jakarta Barat No.: 334/Pid.Sus/2020/PN Jkt.Brt, merupakan putusan pidana terhadap korporasi yang kedua di bidang perpajakan setelah putusan korporasi Asian Agri Group (AAG). Penelitian bertujuan menganalisis pengaturan pertanggungjawaan pidana korporasi dalam perundang-undangan perpajakan serta menganalisis dasar pertimbangan hakim dalam penentuan kesalahan Korporasi PT GSG. Jenis penelitian adalah penelitian normatif dengan pendekatan perundang-undangan dan pendekatan kasus. Hasil penelitian menunjukkan Undang-Undang Perpajakan belum mengatur eksplisit korporasi sebagai subjek hukum pidana perpajakan serta ada ketidaktepatan dasar pertimbangan hakim putusan pidana PT. GSG. Penentuan kesalahan korporasi dapat berdasarkan kesalahan pelaku materiil beserta syarat internal korporasi. Pada akhirnya, teori identifikasi sesungguhnya dapat digunakan sebagai dasar pembenaran penjatuhan pidana korporasi PT. GSG.Kata Kunci: Kesalahan Korporasi; Tindak Pidana; Perpajakan.
Politik Hukum Perubahan Norma Perizinan dan Iklim Investasi Dalam Undang-Undang Cipta Kerja Menggunakan Metode Omnibus Law
Authors: Prasetyo Angga Dwi , Abdul Rachmad Budiono  , Shinta Hadiyantina
Published: July 2022

AbstractThe Job Creation Law passed and enacted in 2020 is a momentual result with the expectation that the Law will create jobs. But after the passage of the Job Creation Law with the use of the omnibus law method, it produced various responses and reactions from the community so that the community also among academics produced pros and cons to the Law. In addition, after the Uncang-Cipta Kerja Law was passed, it has had an impact on the elimination of industries included in the negative investment list, triggering an increase in foreign investment in Indonesia. Based on the description, a problem was formulated: what is the legal politics behind the change in licensing norms and the investment climate in the Job Creation Law using the omnibus law method. The research method used in the writing of this article is the use of legal normative research. The source of legal materials used includes 3 (three) types of legal materials, namely primary legal materials, secondary legal materials, and tertiary legal materials. Legal data collection techniques use a literature research model that analyzes the legal data studied in the form of qualitative and descriptive content analysis. The results showed that the government’s efforts to reduce duplication of regulations through comprehensive legislation are expected to accelerate licensing.Keywords: Omnibus Law; UU Cipta Kerja; Licensing; Investment.
AbstrakUndang-Undang Cipta Kerja yang disahkan dan diundangkan pada tahun 2020 merupakan suatu hasil momentual dengan harapan dari Undang-Undang tersebut ialah menciptakan lapangan kerja. Tetapi pasca pengesahan Undang-Undang Cipta Kerja dengan penggunaan metode omnibus law tersebut menghasilkan berbagai tanggapan dan reaksi dari lapisan masyarakat sehingga masyarakat pun juga dikalangan akademisi menghasilkan pro kontra terhadap Undang-undang tersebut. Selain itu, pasca Undang-Undang Cipta Kerja disahkan telah berdampak pada penghapusan industri yang masuk dalam daftar negatif investasi sehingga memicu peningkatan investasi asing di Indonesia. Berdasarkan uraian tersebut, dirumuskan masalah: apa politik hukum dibalik perubahan norma perizinan dan iklim investasi dalam UU Cipta kerja menggunakan metode omnibus law. Metode penelitian yang dipakai pada penulisan artikel ini ialah penggunaan penelitian normatif hukum. Sumber bahan hukum yang digunakan meliputi 3 (tiga) jenis bahan hukum, yakni materi hukum primer, materi hukum sekunder, serta materi hukum tersier. Teknik pengumpulan data hukum menggunakan model penelitian kepustakaan yang menganalisis data hukum yang diteliti berupa analisis isi kualitatif dan deskriptif. Hasil penelitian menunjukkan bahwa upaya pemerintah untuk mengurangi duplikasi regulasi melalui undang-undang yang komprehensif diharapkan dapat mempercepat perizinan.Kata Kunci: Omnibus Law; UU Cipta Kerja; Perizinan; Investasi.
Exit Plan Terhadap Clerical Eror Pada Putusan Yang Berkekuatan Hukum Tetap: Sebuah Upaya Preventif Terwujudnya Putusan Non-Executable
Authors: Anand Ghansham , Xavier Nugraha
Published: July 2022

AbstractThis study aims to firstly analyze clerical errors in court decisions that have permanent legal force and secondly analyze related legal remedies for clerical errors in court decisions that have permanent legal force. This research is a doctrinal research with a statute approach, a conceptual approach, and a case approach. The results of this study are that first, a clerical error in a court decision that has permanent legal force is an error that is minor in nature or in the form of an accident and is not related to the substance of the judge’s legal considerations and this error can be corrected by the court, even after the judge makes a decision. . Second, legal remedies that can be filed against typos in decisions that have legal force consist of various kinds, but generally the right one is through an application. It is based on nature, complexity, time, cost, and evidentiary.Keywords: Clerical Eror; Non-Executable Judgement; Legal Action.
AbstrakPenelitian ini bertujuan untuk pertama menganalisis kekeliruan pengetikan (clerical eror) dalam putusan pengadilan yang berkekuatan hukum tetap dan kedua menganalisis terkait permohonan terhadap adanya kekeliruan pengetikan (clerical eror) dalam putusan pengadilan yang berkekuatan hukum tetap. Penelitian ini adalah penelitian hukum (doctrinal research) dengan pendekatan perundang-undangan (statute approach), pendekatan konseptual (conceptual approach), dan pendekatan kasus (case approach). Adapun hasil dari penelitian ini adalah pertama kekeliruan pengetikan (clerical eror) pada putusan pengadilan yang berkekuatan hukum tetap adalah kesalahan yang sifatnya ringan atau berbentuk ketidaksengajaan dan tidak berkaitan dengan substansi pertimbangan hukum hakim dan kesalahan ini dapat diperbaiki oleh pengadilan, meskipun setelah hakim menjatuhkan putusan. Kedua, exit plan yang dapat diajukan terhadap adanya kekeliruan pengetikan pada putusan yang berkekuatan hukum terdiri dari beraneka ragam, namun umumnya yang tepat adalah melalui permohonan. Hal ini didasarkan pada hakikat, kompleksitas, waktu, biaya, dan pembuktian. Kata Kunci: Clerical Eror; Putusan Non-Executable; Exit Plan.
High-cycle fatigue S-N curve prediction of steels based on a transfer learning-guided convolutional neural network
Authors: Wei Xiaolu , Wang Chenchong , Jia Zixi , Xu Wei
Published: July 2022

The evaluation and prediction of fatigue properties are crucial for metallic materials. Although the determination of S-N curves represents the most important methods for evaluating such properties, its fatigue testing is costly and time-consuming. Furthermore, fatigue testing involves different test conditions, thereby complicating the evaluation of the fatigue properties. This study develops a transfer convolutional neural network (TR-CNN) framework, in which the prediction of the reversed torsion S-N curves of steels is transferred from rotating bending S-N curves. In the TR-CNN framework, the source CNN models for rotating-bending curve prediction are first trained based on the composition and process conditions. Subsequently, based on the source models, the reversed torsion S-N curves are estimated by training the TR-CNN models based on only a small dataset. After proving the rationality of the framework, its universality with respect to different amounts of data is further investigated. The reversed torsion curves under small-sample conditions (22 samples) are predicted accurately by the TR-CNN. Additionally, the TR-CNN models remain accurate under varying amounts of data (22-112 samples), showing excellent generality for different amounts of fatigue data. The predictive capability of the TR-CNN models is improved by introducing tensile properties into the source models. The proposed TR-CNN framework can significantly reduce the cost of evaluating fatigue properties, and the prediction of S-N curves can be optimized by combining the transfer framework and low-cost properties related to fatigue.
Library local history audio tour: the specifics of creation
Authors: Verkhov A. I.
Published: July 2022

The popularization of local history knowledge, based on the fund of materials about the native land that is being formed by local libraries, includes the use of new information and online technologies. The format of the street audio tour allows the library to get closer to the user, such a tour is «a historian in your pocket». The purpose of this text (based on the experience of creating street audio tours by the our department of local history) is to outline both the real obstacles in creating an audio tour and the underestimated resources of libraries.So, for example, when preparing an audio tour, the libraries' own information resources may be underestimated. But relying on the local history fund the library has every opportunity to create a high quality excursion product. Especially noteworthy resources are the collections of periodicals, city directories and phonebooks  of past years, which allow checking the facts and raising the degree of reliability of the tour.At the same time, one should not overestimate the competencies required for creating an audio tour, including those related to writing texts and working with audio recordings. The advantage of a guide created by non-pros is the possibility of creating an almost intimate one-to-one story. At the same time, librarians undoubtedly need both methodological support and technical advice.
Training and retraining of the library staff in Tajikistan: status and development trends
Authors: Makhmudov G. B.
Published: July 2022

Libraries are an important social institution, significantly influencing the development of econ­omy, science, education and culture. They play the main role in forming the information infrastructure.

The development of librarianship largely depends on the level of material support, the introduction of new technologies, the renewal of collections, as well as on the training of personnel. In many cases, just the problems of education, the level of qualification of the library personnel are decisive for providing population with effective information and library service. The author presents the results of the analysis of the state of library and information education in Tajikistan. The main strategic aspects of the development of higher education in the country are elucidated, as well as the trends in training, advanced training and retraining of library personnel, the problems are indicated and possible ways to solve them are defined.
Using Brains as Sensors of the Magnetic Fields Produced by Other Brains
Authors: Jeuland Énora , Lenne Matthieu , Jarry Florence , Debruille Jacques Bruno
Published: July 2022

The effects of transcranial magnetic stimulations (TMS) show that the human brain is impacted by some magnetic fields (EMFs). Moreover, after a delay, it produces potentials that reveal a subsequent processing of this impact. The human brain might also be sensitive to very weak magnetic fields of extremely low frequencies (vwEMFelf). Namely, to the vwEMelf produced by the brain of other persons when they process visual stimuli. In effect, two studies report that the event-related brain potentials (ERPs) that are evoked by presenting a picture to a participant can be modulated by simultaneously presenting a picture to a partner. To confirm it here, we followed most of the methods of these studies. We recorded the ERPs evoked by presenting, at each trial, the photograph of a face. Simultaneously and, most importantly, privately, we presented a partner with the same or with a different face photograph. ERPs of participants were found to depend on that sameness (p0.001), unbeknownst to them. These joint processing effects (JPEs), confirm a sensitivity of the human brain to the vwEMFelf produced by other brains.
Light Dispersion in Gravitational Field
Authors: Zhu Yin
Published: July 2022

In any region of a space, the gravitational field cannot be eliminated. The speed of light in a vacuum has never been observed and cannot be observed with current technology. Till now, only the speed of light in a gravitational field has been observed. Here, it is presented that light could be dispersion in a gravitational field analogous to the dispersion of light in the Newtonian prism experiment. The relativistic mass density on the surface of a neutron star is on the level of 1017kgm-3 while on the surface of the Earth is only 6.63*10-7kgm-3, the speed of light acted by the gravitational field of a neutron star is much larger than that by the Earth. Therefore, light dispersion in strong gravitational field could be generally observed from the picture of a star and it should have been observed through the spectroscopic binary system.
Reliability of Satellite-Based Rainfall Products for Water Man-agement Studies: the Case of The Ankavia River Basin in Madagascar
Authors: Ramahaimandimby Zonirina , Randriamaherisoa Alain , Jonard François , Vanclooster Marnik , Bielders Charles
Published: July 2022

Hydrological modeling for water management in large watersheds requires accurate spatially-distributed rainfall time series. In case of low coverage density of ground-based measurements, satellite precipitation products (SPP) constitute an attractive alternative, the quality of which must nevertheless be verified. The objective of this study was to evaluate, at different time scales, the reliability of six SPPs against a 2-year record from a network of 14 rainfall gauges located in the Ankavia catchment (Madagascar). The SPPs considered in this study are the African Rainfall Estimate Climatology (ARC2), the Climate Hazards group Infrared Precipitation with Station data (CHIRPS), the ECMWF Reanalysis (ERA5), the Integrated Multi-satellitE Retrievals for Global Precipitation Measurement (IMERG), the Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks (PERSIANN), and the African Rainfall Estimation (REF2) products. The results suggest that IMERG (R² = 0.63, slope of linear regression a = 0.96, root mean square error RMSE = 12 mm/day, mean absolute error MAE = 5.5 mm/day) outperforms other SPPs at the daily scale, followed by REF2 (R² = 0.41, a = 0.94, RMSE = 15 mm/day, MAE = 6 mm/day) and ARC2 (R² = 0.30, a = 0.88, RMSE = 16 mm/day, MAE = 6.7 mm/day). All SPPs, with the exception of the ERA5, overestimate the ‘no rain’ class (0 – 0.2 mm/day). ARC2, IMERG, PERSIANN, and REF2 all underestimate rainfall occurrence in the 0.2 – 150 mm/day rainfall range, whilst CHIRPS and ERA5 overestimate it. Only CHIRPS and PERSIANN could estimate extreme rainfall (>150 mm/day) satisfactorily. According to the Critical Success Index (CSI) categorical statistical measure, IMERG performs quite well in detecting rain events in the range 2-150 mm/day, whereas PERSIANN outperforms IMERG for rain events larger than 150 mm/day. Because it performs best at daily scale, only IMERG was evaluated for time scales other than daily. At the yearly and monthly time scales, the performance is good with R² = 0.97 and 0.87, respectively. At the event time scale, the probability distribution function PDF of rain gauge values and IMERG data show good agreement. However, at hourly time scale, the correlation between ground-based measurements and IMERG data becomes poor (R2 = 0.20). Overall, the IMERG product can be regarded as the most reliable satellite precipitation source at monthly, daily and event time scales for hydrological applications in the study area, but the poor agreement at hourly time scale and the inability to detect extreme rainfall >200 mm/day may nevertheless restrict its use.
A Critical Analysis of Decentralizing the Portuguese Public Healthcare Provision Services
Authors: Nunes Alexandre Morais , Ferreira Diogo Cunha
Published: July 2022

The Portuguese health system has a universal, public, general National Health Service (NHS), tending towards free healthcare access. Created in 1979, this delivery model developed from the integration and complementarity between the different response levels (primary, hospital, continuing, and palliative care). However, over these 40 years, the initially centralized system underwent a decentralization process with the creation of Regional Health Administrations in the five mainland administrative regions. Since then, the entire NHS has settled around this new organization. The most recent step started in 2018 with decentralizing primary health care skills to 190 municipalities. This paper presents the various critical issues involved in the latest gradual decentralization process in health, intending to bring services closer to the citizens, and more focused on their needs. The article identifies and discusses the implications of this experience based on the steps foreseen in the already published legal texts.
Effects of MWCNTs on Char Layer Structure and Physicochemical Reaction in Ethylene Propylene Diene Monomer Insulators
Authors: Chen Zhiheng , Han Shida , Ji Yuan , Wu Hong , Guo Shaoyun , Yan Ning , Li Hongyan
Published: July 2022

As one of the most promising ablative fillers, multi-walled carbon nanotubes (MWCNTs) have been used to improve the ablative resistance of Ethylene-Propylene-Diene Monomer (EPDM) insulators by facilitating the carbothermal reduction reaction of silica. However, the contribution of MWCNTs to char layer structure of the insulators was unclear. In this work, the effects of MWCNTs on char layer structure and ablative resistance were investigated in different EPDM-based insulators with and without silica. The results showed that adding only 3 phr MWCNTs can reduce the linear ablation rate of EPDM-based insulators without silica by 31.7%, while 6 phr MWCNTs are required to obtain similar results in EPDM-based insulators with silica. Both the char layer morphology of the two insulators gradually evolved into dense porous structure as MWCNTs content increasing, but their formation mechanisms are different. The XRD and Raman spectrum showed that different physicochemical reactions occurred around MWCNTs under different charring components. The proposed ablation mechanism was further verified by designing alternating multilayer distribution of MWCNTs and silica. This work can guide the construction of desirable char layer structure for increasing ablative resistance of EPDM-based insulators.
Vitamin D-related Genetic Variations and Non-alcoholic Fatty Liver Disease: a Systematic Review
Authors: Jaroenlapnopparat Aunchalee , Suppakitjanusant Pichatorn , Ponvilawan Ben , Charoenngam Nipith
Published: July 2022

Background: Studies have demonstrated the link between vitamin D-related genetic variations and non-skeletal outcomes. We aimed to identify all available data on the association of vitamin D-related genetic variations with non-alcoholic fatty liver disease (NAFLD).
Methods: Potentially eligible studies were identified from Embase and Medline databases from inception to June 2022 using search strategy that comprised terms for “Vitamin D” and “NAFLD”. Eligible study must report the association between vitamin D-related genetic variations and presence, severity or response to treatment of NAFLD. Data were extracted from each eligible study.
Results: A total of 3,495 articles were identified. After systematic review, twelve studies were in-cluded. A total of 26 genetic variations were identified. Presence of NAFLD was associated with variations of GC (rs222054, rs222020, rs10011000, rs7041), VDR (rs2228570, rs11168287, rs10783219, rs4752), CYP24A1 (rs3787557, rs6068816, rs2296241, rs2248359) and CYP27B1 (rs4646536). Severity of NAFLD was associated with variations of GC (rs4588), VDR (rs2228570, rs4334089), CYP2R1 (rs10741657), DHCR7 (rs1544410, rs3829251, rs12785878) and CYP24A1 (rs3787557, rs6068816, rs6097809, rs6127119, rs2248359, rs3787554, rs4809960, rs6022999). Response to calcitriol treatment was associated with variation of VDR (rs10735810).
Conclusions: Multiple vitamin D-related genetic variations were associated with NAFLD, indi-cating the role of vitamin D in the pathogenesis of NAFLD.
Psychological Distress in South African Healthcare Workers early in the COVID-19 Pandemic: An Analysis of Associations and Mitigating Factors
Authors: Lee Hsin-Ling , Wilson Kerry , Bernstein Colleen , Naicker Nisha , Yassi Annalee
Published: July 2022

While the global COVID-19 pandemic has been widely acknowledged to affect the mental health of health care workers (HCWs), attention to measures that protect those on the front lines of health outbreak response has been limited. In this cross-sectional study, we examine workplace contextual factors associated with how psychological distress was experienced in a South African setting where a severe first wave was being experienced with an objective of identifying factors that can protect against HCWs experiencing negative impacts. Consistent with mounting literature on mental health effects, we found a high degree of psychological distress (57.4% above General Health Questionnaire cut-off value) and a strong association between perceived risks associated with the presence of COVID-19 in the healthcare workplace and psychological distress (adjusted OR = 2.35, p <.01). Our research indicates that both training (adjusted OR 0.41, 95% CI 0.21 – 0.81) and the reported presence of supportive workplace relationships (adjusted OR 0.52, 95% CI 0.27 – 0.97) were associated with positive outcomes. This evidence that workplace resilience can be reinforced to better prepare for the onset of similar outbreaks in the future suggests that pursuit of further research into specific interventions to improve resilience is well merited.
Argentina’s fertility regime (1980-2010): the end of the first demographic transition or an emergent second one?
Authors: Mertehikian Yasmin
Published: July 2022

Argentina’s fertility transition has exceptional characteristics. Compared to most Latin American countries, Argentina’s fertility declined relatively early and, unlike fertility transitions in Western Europe, this decline did not lead to a high period of natural population growth. By the beginning of the twenty-first century, Argentina seemed to experience fertility stagnation despite women’s increased formal education and labor force participation, and increased availability of contraceptives. Using the 1980, 1991, 2001, and 2010 Population Censuses, I demonstrate that fertility has continued its downward trend from 1980 to 2010. Changes in fertility behaviors are given by a decrease in the mean number of children per woman, but not by an increase in childlessness. However, there is evidence of postponement of childbearing. Results show that although Argentina is completing its first demographic transition, as it has not reached below-replacement fertility yet, this country could show signs of an emerging second demographic transition.
FORMALIZATION OF THE PROCESS OF PREPARATION OF THE TEACHERS STUDYLOAD PLAN OF THE HIGHER EDUCATION INSTITUTION DEPARTMENT
Authors: Dvukhhlavov Dmytro , Bezmenov Mykola , Shmatko Oleksandr , Dvukhhlavova Alona , Korkhovyi Dmytro , Cherkun Mykyta
Published: July 2022

A formalized description of the process of planning the studyload of teachers of the department for the academic year at the department of higher education institution. The relevance of presenting the model in a formalized form is determined by the need to have a unified view of the processes of preparation of the required data, principles and algorithms of data transformation, as well as to unify the results of presenting the final results. The proposed formalized description is considered as a basis for further creation of an automated system for calculating and distributing studyload with the possibility of automated generation and distribution of reporting documents, including semester plan and studyload plan, and personal extracts for preparing part "Educational work" in teacher’s individual plans. The presented process reflects the peculiarities of the distribution and presentation of initial data and results of studyload planning at a particular department of a particular institution of higher education in Ukraine. The Enterprise Architect design support system was used to prepare the models, and therefore the proposed formalized description can be adapted to the specifics of another higher education institution or its department. The basis of the formalized description is the domain model. Each of the essentials of the domain model is represented by a set of attributes that allows the use of description tuples in the design of the database of the respective software system. The stages of training load planning in the form of BPMN business process diagrams and UML activity diagrams are defined. Mathematical relations and descriptions of the order of calculations are presented, which allow to obtain the set values of the values at certain stages of the plan formation. The proposed results are obtained on the basis of the regulatory framework of Ukraine in the field of education.
PROBLEM OF CLASSIFICATION OF SEMANTIC KERNELS OF WEB RESOURCE
Authors: Orekhov Sergey , Malyhon Hennadiy , Stratiienko Nataliia
Published: July 2022

The article presents a new theoretical basis for solving the problem of situational management of semantic cores identified on the basis of WEB content. Such a task arises within the framework of a new phenomenon called virtual promotion. Its essence lies in the fact that a real product can exist in two realities: online and offline. According to marketing theory, the lifetime in two realities is the same. However, in the online mode, the goods exist independently and in accordance with the laws of the use of Internet technologies. Therefore, based on the concept of a marketing channel, it was proposed to consider a message in such a channel as a semantic core. The core is a specially selected set of keywords that briefly describe the product and the corresponding need. It has been proposed that each need forms a so-called class of need. Therefore, the product description will either belong to this class or not. In addition, a product can be described by a different set of keywords, which means that different descriptions of the same product or several products, if there are any for sale in the enterprise, will fall into the demand class. As a result, in this work, it was proposed to consider the center of this class as the so-called K-candidate. It is the K-applicant that will be the semantic core that will be considered at the current iteration of the situational management process. In addition, in order to move from one situation to another, in other words, from one core to another, it is required to have such an alternative core. It can be safely taken either from the neighborhood of the need class center (K-applicant), or the center of another class (another K-applicant), if the product can cover several needs of a potential buyer. Then the actual task is to classify the classes of needs based on the text corpus in HTML format. Having a text corpus at the first stage, the task of synthesizing semantic cores is realized, and then the classification task itself. This article proposes the formulation of the classification problem, taking into account the features that the Internet technologies contribute to search engine optimization. In particular, it is proposed to use four metrics from the category of WEB statistics. And then it is proposed to use the clustering method to identify classes of needs, taking into account the fact that the K-applicant is presented as a semantic network or as a graph.
The Mexican Consortium of Epidemiological Studies for the Prevention, Diagnosis, and Treatment of Chronic Kidney Disease: a review of collaborating studies
Authors: Cortés-Valencia Adrian , Ortiz-Rodríguez Saraí , Balderas-Arteaga Nydia , Catzin-Kuhlmann Andrés , Correa-Rotter Ricardo , González-Villalpando Clicerio , Jiménez-Corona Aida , López-Ridaura Ruy , Mejia Miguel , Salmerón Jorge , Tamayo Juan , Lajous Martín , Denova Gutiérrez Edgar
Published: July 2022

Objective. To harmonize participants’ information from five epidemiological studies. Materials and methods. The Mexican Consortium of Epidemiological Studies for the Prevention, Diagnosis, and Treatment of Chronic Kidney Disease (RenMex, by its Spanish acronym) was established in 2018. RenMex is a consortium of five studies: The Mexican Teachers Cohort Study; the Mexico City Diabetes Study; the Health Workers Cohort Study; the Comitán Study; and the Salt Consumption in Mexico Study, which assessed baseline serum creatinine, albumin, and C-reactive protein, all performed with standardized techniques. Results. RenMex includes 3 133 participants, with a mean age of 44.8 years, 68.8% women, 10.8% with a previous medical diagnosis of type 2 diabetes, and 24.1% living with obesity. Conclusions. In the future, RenMex will work on more detailed analyses with each cohort allowed to opt in or out for each topic according to their individual data.
Prevalence and factors associated with the depressive symptoms in rural and urban Mexican older adults: evidence from the Mexican Health and Aging Study 2018
Authors: García-Pérez Alvaro , González-Aragón Pineda Alvaro Edgar , Sandoval-Bonilla Bayron Alexander , Cruz-Hervert Luis Pablo
Published: July 2022

Objective. To determine the prevalence and factors related to depressive symptoms in older Mexican adults in urban and rural areas. Materials and methods. Cross-sectional study. We examined older adults from a sample taken from the Mexican Health and Aging Study (MHAS-2018). 14 230 older Mexicans were screened for self-reported depressive symptoms. Results. The prevalence of depressive symptoms was 29.8% (33.4% rural vs. 28.9% urban). In the rural and urban population, the probability of a high prevalence of depressive symptoms was higher in older adults with multimorbidity ≥3, severe pain, and fair/poor SRH. Only in the urban population the prevalence of depressive symptoms increased with lower schooling. Conclusion. Identification of the factors related to depressive symptoms may help healthcare professionals provide better treatment for specific groups in the population.
Effect of Mexico’s vaccination program on Covid-19 cases, hospitalizations, and deaths among older adults in Mexico City
Authors: Gasca Natalie C , Reyes-Garza Jose , Lozano-Esparza Susana , Orozco-del Pino Pedro , Olivas-Martinez Antonio , Ulloa-Pérez Ernesto , Garbuno-Inigo Alfredo , Arroyo Jesús
Published: July 2022

Objective. To characterize the impact of Mexico’s Co­vid-19 vaccination campaign of older adults. Materials and methods. We estimated the absolute change in sympto­matic cases, hospitalizations and deaths for vaccine-eligible adults (aged >60 years) and the relative change compared to vaccine-ineligible groups since the campaign started. Re­sults. By May 3, 2021, the odds of Covid-19 cases among adults over 60 compared to 50-59 year olds decreased by 60.3% (95%CI: 53.1, 66.9), and 2 003 cases (95%CI: 1 156, 3 130) were avoided. Hospitalizations and deaths showed similar trends. Conclusions. Covid-19 events decreased after vaccine rollout among those eligible for vaccination.
Inhibition of extracellular and intracellular survival of Mycobacterial strains by alkaloids extracted from Justicia adhatoda leaves.
Authors: Mishra Smita , Khatri Manisha , Mehra Varsha
Published: July 2022

Tuberculosis (TB) continues to be one of the world's leading causes of death by the infectious pathogen Mycobacterium tuberculosis, which infects one-third of the global population. The emergence of the COVID-19 pandemic made its spread rapid and the treatment task more daunting. With the havoc of infectious disease expansion, traditional medicines have triggered tremendous interest worldwide. However, less availability of scientific evidence still hinders its practical use. In the present study, we evaluated the potential of the traditional medicinal plant, Justicia adhatoda, which has been used to treat respiratory ailments since ancient times. We have successfully isolated and characterized several bioactive compounds viz- Vasicoline, Vasicolinone, Adhatodine, Adhavasine, Aniflorine, and Vasicinone from J. adhatoda plant leaves, including Vasicine as the principal compound, and showed their anti-tubercular activity on nutrient-starved Mycobacterium smegmatis and Mycobacterium bovis. The study also directs their in-vitro and ex-vivo antimycobacterial potential on THP1 macrophages with internalized Mycobacterium. Our study is one of its first kind, where we assessed the synergistic antimycobacterial effect of the isolated compounds with the first-line drug Isoniazid (INH). Their potential role in promoting phagolysosome fusion and apoptosis of M. bovis infected THP1 macrophages is further evaluated.
Analysis of the phase velocities of (Pure, Slow and Fast ) Alfvèn waves in the E region of the ionosphere for low latitudes
Authors: kurt kadri
Published: July 2022

In this paper, (pure, slow, and fast) Alfvèn waves for the accepted conditions in Northern-hemisphere at E-region of ionospheric plasma were calculated with low latitudes by using Eq. (20,25-26) and the real geometry of Earth’s magnetic field, at hours 12.00 LT for the 1990 year which sunspot is maximum. One of the most important results of this study is to show analytically that the “MHD modes= (pure, slow and fast) Alfvèn waves” depend not only on the angle between the wave propagation vector (k) and the magnetic field (B) but also on the declination (D=It is the angle value between the direction of the sun's rays and the equatorial plane) and magnetic dip angle (I=It is the angle between real north and magnetic north). From the results obtained, the behavior of the magnitudes of the squares of the phase velocities of all MHD modes is consistent with the behavior of the distribution of electron density with low geographic latitude, even if the magnetic field vector is both perpendicular and parallel to the propagation vector of the wave. In parallel, the phase velocities of the waves are greater in summer than in winter. It has been determined that the propagation velocities of the fast and slow MHD mode in the magnetic equatorial trough region at (q = I) are very small, the energy is almost non-existent, but if q = 90 + I, the energy increases with latitude and is approximately maximum at the low latitude limit. It can be said that the minimum points are between 0-10 oN latitudes where the wave energies are the smallest, and the maximum points are between 20-30 oN latitudes the wave energies are the biggest.
Isoflavones have a potential role to play in off-flavour scavenging, with Isoflavone synthase 2 (IFS2) as a key player determining isoflavone accumulation in soybean seeds
Authors: Kumar Sandeep , Banerjee Sagar , Kaur Amandeep , Sasi Minnu , Kumari Sweta , Sachdev Archana , Dahuja Anil
Published: July 2022

Soybean (Glycine max (L.) Merr) is a nutrient-rich crop with limited consumer acceptability because of the presence of off-flavour. Owing to the ubiquity of isoflavones in soybean, their inherent antioxidant potential, and inhibitory effect on lipoxygenase activity, their sensorial attribute in mitigating off-flavour is currently being envisaged. We estimated the content and composition of isoflavones in 17 soybean cultivars and established the correlation between isoflavone profile and lipid peroxidation, which was measured in terms of Thiobarbituric acid (TBA) number and carbonyl value. The results showed a significant negative correlation of these parameters with the total isoflavone content and genistein: daidzein ratio. Besides, expression analysis of a key gene involved in isoflavone biosynthesis, i.e., isoflavone synthase (IFS1 and IFS2) in contrasting soybean genotypes during seed development revealed a higher expression of both isoforms in Bragg (High isoflavone) as compared to PUSA 40 (Low isoflavone) at different stages of seed development accompanied by more isoflavone accumulation. The cloning and in silico analysis of IFS isoforms revealed a more significant interaction with other biosynthesis enzymes by the IFS2, indicating its more substantial role in isoflavone synthesis. IFS2 overexpression thus can be a valuable target to increase isoflavone biosynthesis, thereby scavenging off-flavour.
Association between problematic use of smartphones and mental health in the Middle East and North Africa (MENA) region: a systematic review
Authors: bouazza samira , Elkinany Soukaina , ABBOUYI Samira , RHAZI Karima El , ZARROUQ Btissame
Published: July 2022

Background
Smartphones have become essential components of daily life, and research into the harmful effects of problematic smartphone use (PSU) on mental health is expanding globally. Although several recent studies have addressed the relationship between PSU and mental health in the Middle East and North Africa (MENA) region, this issue has yet to be synthesized and critically evaluated.
Methods
To find quantitative observational studies on the relationship between PSU and mental health in the MENA region, we developed a search strategy based on a search equation and adapted it for four databases. The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were followed during the selection process. This review included approximately 33 cross-sectional studies and one cohort study out of the 6423 studies identified. The only available language was English. All identified studies published until October 8th, 2021, were considered. A modified Newcastle-Ottawa scale was used to assess the quality of the included studies, as we were interested in three mental health outcomes: depression, anxiety, and stress.
Results
The studies enrolled 21696 people and had low to moderate methodological quality. The prevalence of PSU ranges from 4.3 percent to 97.8 percent. The time factor (average duration of use per day, frequency of use, consultation during the night), type of application used on the smartphone, and socio-demographic characteristics were the determinants of PSU (age, gender, marital status). Depression, anxiety, and stress were all strongly correlated with PSU, with a stronger relationship between PSU and depression (0.164 ≤ r ≤ 0.996) than between PSU and anxiety (0.12 ≤ r ≤ 0.562) or stress (0.14 ≤ r ≤ 0.508).
Conclusions
PSU is a real public health issue because it is linked to mental illnesses and social dysfunctions that are a wearisome burden on society. As a result, more epidemiological studies, particularly longitudinal ones that respect the quality of evidence, are needed in all MENA countries to better plan, and implement preventive measures to avoid devastating complications for individuals and societies.
Systematic review registration:
an a priori protocol is registered on PROSPERO under the number CRD42022266732.
Prenatal methamphetamine hydrochloride exposure leads to signal transduction alteration and cell death in the prefrontal cortex and amygdala of male and female rats’ offspring
Authors: Maghsoudi Nader , Zare Nayereh , Mirbehbahani Seyed Hamidreza , Khodagholi Fariba , Khakpour Shahrzad , Mansouri Zahra , Yekta Batool Ghorbani
Published: July 2022

Background
In the last decade, there has been a great increase in methamphetamine hydrochloride (METH) abuse by pregnant women that exposes fetus and human offspring to a wide variety of developmental impairments that may be the underlying causes of future psychosocial issues.
Objective
Herein we investigated whether prenatal METH exposure with different doses (2 and 5mg/kg) could influence neuronal cell death and antioxidant level in the different brain regions of adult male and female offspring.
Methods
Adult male and female Sprague–Dawley rats prenatally exposed to METH (2 or 5mg/kg) and/or saline was used in this study. At week 12 adult rats' offspring were decapitated to collect different brain region tissues including amygdala (AMY), anterior cingulate cortex (ACC), and prefrontal cortices (PFC). Western blot analysis was performed to evaluate the apoptosis and autophagy related markers, and enzymatic assay was used to measure the level of catalase and also reduced glutathione (GSH).
Results
Our results showed that METH exposure during pregnancy increased the level of apoptosis (BAX/Bcl-2 and Caspase-3) and autophagy(Beclin-1 and LC3II/LC3I) in the PFC and AMY area of both male and female offspring’s brain. Also, we found an elevation in the GSH content of all three mentioned brain areas and catalase activity of PFC in the offspring's brain.
Conclusion
Prenatally exposure to METH increased cell death at least partly via apoptosis and autophagy in AMY and PFC of male and female offspring’s brain, while the antioxidant system tried to protect cells in these regions.
Evolution of moist wound healing: Methods of autologous tissue regeneration
Authors: Yamamoto Kenji , Miwa Senri , Yamada Tomoyuki , Setozaki Shuji , Hamuro Mamoru , Kurokawa Shunji , Enomoto Sakae
Published: July 2022

Since the first report of an autologous tissue regeneration technique in 1962, hydrocolloids have been widely used for wound closure. However, complete closure of the wound may result in an infection, which is a major setback. Several dressing types have been unable to circumvent this issue and are not recommended in infected wounds. Wound infection is difficult to determine; in several countries, the wound is often covered with conventional gauze rather than a covering material. The novel ability of irreversible membrane dressings to absorb leachate irreversibly while retaining surface moisture has dramatically improved outcomes in Japan. Our results show that moist wound healing maximizes autologous tissue regeneration, hastens epithelialization, and reduces infection.
Development of a MAGIC population and high-resolution quantitative trait mapping for nicotine content in tobacco
Authors: Yuan Guangdi , Sun Kefan , Yu Wenlong , Jiang Zipeng , Jiang Caihong , Liu Dan , Wen Liuying , Si Huan , Ren Min , Wu Fengyan , Meng He , Cheng Lirui , Yang Aiguo , Wang Yuanying
Published: July 2022

Multiparent Advanced Generation Inter-Cross (MAGIC) populations are ideal genetic and breeding materials for quantitative trait locus (QTL) mapping and molecular breeding. In this study, a MAGIC population derived from eight tobacco parents was developed. Eight parents and 560 homozygous lines were genotyped by a 430K single-nucleotide polymorphism (SNP) chip assay and phenotyped for nicotine content under different conditions. Four QTLs associated with nicotine content were detected by genome-wide association mapping (GWAS), and one major QTL, named qNIC5-1, was mapped repeatedly under different conditions. Furthermore, by combining forward mapping, bioinformatics analysis and gene editing, we identified an ethylene responsive factor (ERF) transcription factor as a candidate gene underlying the major QTL qNIC5-1 for nicotine content in tobacco. A presence/absence variation (PAV) at qNIC5-1 confers changes in nicotine content. Overall, the large size of this MAGIC population, diverse genetic composition, balanced parental contributions and high levels of recombination all contribute to its value as a genetic and breeding resource. The application of the tobacco MAGIC population for QTL mapping and detecting rare allelic variation was demonstrated using nicotine content as a proof of principle.
River Mouth Shifting and Horeline Change Analysis of Mangala River Mouth at Puri Coastline
Authors: Mishra Debabrata , Kar Anil Kumar
Published: July 2022

The shoreline environment has been considered as a major concern in most of the parts of the globe. A significant trend of both erosion and accretion are primarily experienced on the Puri coast of Bay of Bengal at mouth of river Mangala. The sand dunes are formed, so the river mouth is shifting towards town and a new mouth is beginning. The satellite images from the year 1998 to 2021 are used to detect the shoreline change and the river mouth shifting. The GIS tools as well as a compatible tool bar Digital Shoreline Analysis System (DSAS) has been used to delineate the shoreline change and its corresponding hazards. It is found that, the shoreline of Mangala river mouth is accredited with an average rate of accretion of 3.49 m/yr. Total forty number transects are formed along with none as erosional transects which means all the transects formed undergo 100% of accretion. The percent of all transects that have statistically significant to accretion is 87.5%. The maximum value of accretion is 6.11 m/yr. This research intends to describe possible causes and consequences of shoreline changes of the Mangala river mouth and need for necessary precautionary measures.