bluuebunny/crossref_metadata_2025 huggingface dataset:
Pattern of Cybercrime among Adolescents: An Exploratory Study
Authors: SHAHJAHAN Mohammad , MIAH Abdul Kader
Published: February 2024

Background: Cybercrime is common phenomenon at present both developed and developing countries. Young generation, especially adolescents now engaged internet frequently and they commit cybercrime frequently in Bangladesh. Objective: In this regard, the present study on the pattern of cybercrime among youngers of Bangladesh has been conducted. Methods and tools: This study was a cross-sectional study, descriptive in nature. Non-probability accidental sampling technique has been applied to select the sample because of the nonfinite population and the sample size was 167. A printed semi-structured questionnaire was used to collect data. Results: The study shows that adolescents mainly do hacking (94.6%), pornography (88.6%), software piracy (85 %), cyber theft (82.6%), credit card fraud (81.4%), cyber defamation (75.6%), sweet heart swindling (social network) (65.9%) etc. as cybercrime. According to findings the major causes of cybercrime among the respondents in Bangladesh were- weak laws (88.0%), defective socialization (81.4%), peer group influence (80.2%), easy accessibility to internet (74.3%), corruption (62.9%), unemployment (58.7%), and poverty (24.6%) etc. It is evident from the study that 91.0% respondents used password cracker as the techniques of cyber criminality. About 76.6%, 72.5%, 71.9%, 68.3% and 60.5% respondents’ technique was key loggers, network sniffer, exploiting, vulnerability scanner and port scanner consecutively. Conclusion: The study concluded that pattern of cybercrimes is frequently changing and increasing dramatically. Finally, it is recommending that the private public partnership and execution of existing laws can be controlling this crime.
Cloud Penetration Testing
Authors: MIHALACHE Denisa-Nicoleta
Published: February 2024

The utilization of cloud computing has been growing exponentially, becoming the preferred platform for businesses of all sizes, from start-ups to large corporations. However, this shift towards cloud computing brought about the responsibility to ensure the security of cloud applications and data from malicious attacks. The joint responsibility model of cloud security requires both service providers and businesses to maintain security. Identity and access management are shared responsibility models, requiring protocols and ethical hacking to ensure data protection. Advanced security measures like penetration testing are essential to establish a secure virtual environment. The primary aim of this research paper is to demonstrate how important penetration testing is for an organization even with security features that cloud providers implemented.
Islamism and Jihad: The Problem With Western Taxonomies
Authors: Mohamed Mohamed Mosaad Abdelaziz
Published: February 2024

Explaining the confusing classification of 'political Islam' as Islamism/Jihad, I argue that this classification is epistemologically grounded in 1) Christian morality, 2) political secularism, and 3) modern ideologism. I contrast this epistemology to an Islamic-friendly epistemology, framed by a specific theory of meaning, a priority of historical cases over abstract principles in determining the correct action, and a priority of the apparent action in deciding its rule legally over any internal intention or implied subjectivity. Following this discussion, I propose and introduce four legal concepts that traditionally articulate Muslims’ political protest: 1) jihad, 2) khurūj, 3) qitāl al-fitnah, and 4) naṣīḥah. Contrasting this legal classification against the conventional Islamism/Jihad classification, I explain the advantages of using Islamic-friendly concepts to understand and frame Muslims’ political protest. I also explain that these four concepts are essentially neither good nor evil, neither true nor false. They are rooted neither in ideology nor in morality. They are legal concepts where each one of them can be ruled, depending on a specific historical situation, as wājib, mustaḥab, mubāḥ, makrūh, or ḥarām.
Educating to the “Culture” of Quantum Technologies: A Survey Study on Concepts for Public Awareness
Authors: Seskir Zeki Can , Goorney Simon Richard , Chiofalo Maria Luisa
Published: February 2024

In this article we offer a conceptual and practical contribution to the field of STEM education by investigating the concepts educators may include in Quantum Technologies (QT) outreach activities. We embed our approach in the discipline-culture (DC) framework, in which we consider the cultural nuances of QT as an important factor which must not be ignored in education efforts. To this end, a survey study by the pilot project Quantum Technologies Education For Everyone (QuTE4E), investigating key concepts for QT outreach, was conducted between December 2021 and June 2022. Here we present the results of the study, analysed through the DC framework, and consider the implications for designing QT outreach activities. The data hints at the perceived value of highlighting core concepts of Quantum Mechanics (QM), while also raising the question of whether QT sits as a discipline of Physics, Computer Science, or elsewhere. This calls for a reordering of the primacy of certain concepts (such as qubit and spin) for outreach purposes, where core concepts in QM might not be core concepts in QT, and vice versa. The results of this study provide valuable insights for those interested in learning more about this rapidly-evolving field.
Pengaruh Pendanaan Iklim terhadap Penurunan Emisi Karbon melalui Energi Terbarukan di Indonesia
Authors:   Departemen Ilmu Ekonomi, Fakultas Ekonomi dan Bisnis, Universitas Padjadjaran, Evitasari Noviani , Komarulzaman Ahmad ,   Departemen Ilmu Ekonomi, Fakultas Ekonomi dan Bisnis, Universitas Padjadjaran
Published: February 2024

Perubahan iklim menimbulkan berbagai dampak negatif bagi kehidupan sehingga memerlukan tindakan mitigasi dan adaptasi. Pendanaan iklim dapat berperan untuk mendukung transisi ekonomi rendah karbon secara global, termasuk Indonesia. Namun, penelitian empiris mengenai pendanaan iklim di Indonesia masih terbatas. Studi ini menggunakan analisis jalur untuk mengkaji hubungan antara pendanaan iklim, bauran energi terbarukan, dan emisi karbon di Indonesia dari tahun 1973–2020. Hasil menunjukkan bahwa pendanaan iklim tidak dapat secara langsung mengurangi emisi karbon. Pendanaan iklim juga tidak dapat mendorong energi terbarukan untuk menurunkan emisi karbon. Temuan ini mengindikasikan perlunya realokasi pendanaan iklim ke sektor-sektor yang memiliki potensi pengurangan karbon di Indonesia.
Methods of improving the detection of defects in thermograms on the example of GFRP testing
Authors: Swiderski W
Published: February 2024

In non-destructive testing using infrared thermography, we deal with disturbances of the temperature field on the surface of the tested objects, which are not caused by subsurface defects. In order for the thermograms to be free from interference and to have clearly distinguished features of interest to us, a number of image processing algorithms are used. In the article, on the example of non-destructive testing of the GFRP composite by pulse thermography, the effectiveness of various image processing algorithms was compared. In the algorithms used, there is a mechanism to increase the signal/noise ratio and thus increase the effectiveness of defect detection. It should be noted that each processing of the thermogram leads to distortion and the point is only that this distortion is beneficial from the point of view of the purpose of non-destructive testing, i.e. detection of defects and evaluation of their parameters.
DC-Fire: a Deep Convolutional Neural Network for Wildland Fire Recognition on Aerial Infrared Images
Authors: Ghali Rafik , A. Akhlouf Moulay
Published: February 2024

This paper presents a novel deep learning method, called DC-Fire, for recognizing wildland fires using aerial infrared images. Experimental results show that DC-Fire achieved a high performance with an accuracy of 100% and an F1-score of 100% using a large dataset and data augmentation techniques, better than classical machine learning and baseline CNN methods. In addition, DC-Fire demonstrated its potential in detecting smoke and flames, surpassing challenges including small areas of fire/smoke, background complexity, and the variability of forest fires in terms of size, shape, and intensity.
Numerical and experimental analysis for flaw detection in composite structures of wind turbine blades using active infrared thermography
Authors: Figueiredo A. A. A , D’Alessandro G , Perilli S , Sfarra S , Fernandes H
Published: February 2024

Using composite materials in turbine blades has become common in the wind power industry due to their mechanical properties and low weight. This work aims to investigate the effectiveness of the active infrared thermography technique as a non-destructive inspection tool to identify defects in composite material structures of turbine blades. Experiments were carried out by heating the sample and capturing thermographic images using a thermal camera in four different scenarios, changing the heating strategy. Such a preliminary experiments are prodromic to build in the future the so-called optimal experiment design for thermal property estimation. Numerical simulations were carried out to present solutions for improving defect detection. It was demonstrated that active infrared thermography is an efficient technique for detecting flaws in composite material structures of turbine blades. This research contributes to advancing knowledge in inspecting composite materials.
Using autoencoders to reduce noise from infrared thermal imaging of carbon fiber reinforced polymer plates
Authors: Moraes Neto P , Fernandesand H. C , Fontana C. M. C
Published: February 2024

Noise in data can generate difficulty and even inaccuracy in its analysis. In some activities where diagnoses must have good technical precision, such as medical and dental examinations, non-destructive tests on industrial materials, agricultural monitoring, and others, noise present in the data can disturb this precision. In this work we present a statistical learning model, based on convolutional neural networks, capable of removing synthetic noise in infrared thermal images, obtained from a carbon fiber reinforced polymer plate.
Infrared thermography investigation of the mechanical and thermal properties of laser-shocked Ti64
Authors: Iziumova A , Vshivkov A , Sabirov R , Gachegova E , Plekhov O
Published: February 2024

Laser shock peening (LSP) is widely used for improving mechanical and fatigue properties of metals. It uses high power laser radiation to create shock waves. The resulting plastic deformation and microstructural changes create a complex combination of tensile and compressive residual stress fields. This affects the mechanical and thermal behaviour of the laser-shocked material. Infrared thermography (IRT) could be used to define the thermodynamic state of the laser-shocked material under load and to optimize the LSP mode for different geometries and loading conditions. This work investigates the thermal properties and thermomechanical behaviour of laser-shocked Ti64 under quasistatic tensile using IRT.
Pulse Phase Thermography for Panel Paintings Inspection in Mid-wave and Longwave Infrared Bands.
Authors: Kouser H , Boubanga Tombet S , Carrock J , Detalle V , Calligaro T , Bai X , Semerok A
Published: February 2024

Active infrared thermography has demonstrated an ability to retrieve critical sub-surface level information relevant to historical conservation efforts aiming to better understand and preserve multi-layered panel paintings. Complementary use of two Telops infrared cameras (Mid and Long Wave IR), a pulsed thermography system, and pulsed phase thermography processing software, has shown an ability to detect underlying drawings and pentimenti [1]. Further developments on this work have now shown an ability to detect structural components in situ, and preparatory surface irregularity across canvas layers. This non-destructive approach provides critical information to art preservationists and should be considered for broader adoption.
Quantitative Analysis of Pedal Ulcerations Using Thermographic Images
Authors: Dhanalakshmi M , Deepa Rohini T , Fowziya Begum A , Komatheswari T
Published: February 2024

Thermographic images are widely used in diagnosing Diabetic foot (DF) infection and ulceration that are associated with neurological abnormalities. Thermographic images of various diabetic foot ulcerated conditions are collected from 60 patients. There are twenty different types of conceptual foot patterns occurring in diabetic patients, out of which most predominantly observed are type 3A, type 1D, type 3D, type 4D. This work proposes on developing an automatic algorithm to match these diabetic thermographic images of ulcerated foot with conceptual template rather than manually comparing it with the thermogram datasheet. A conceptual template is created using the thermogram datasheet for each of these twenty patterns by edge mapping and curvelet technique. About 60 thermographic images of diabetic foot that have the most predominant patterns are taken for study. These images are pre-processed and segmented for ulcerated region of interest. A pattern for these thermographic images is generated using edge mapping technique and Hough transform. The broken edges are joined by curvelet technique to form a pattern. Each of these patterns is compared with the twenty conceptual templates by template matching technique and an overall efficiency of about 95.27 percent is achieved. This automated algorithm helps the physicians in finding the accurate type of diabetic foot and it is possible to detect the pre-signs of ulcerations in foot.
Mitigating flash flooding in the city: Drain or harvest?
Authors: Siphambe Tebogo V. , Aliyu Abdurrahman , Souadji Kawter , Bayongwa Samuel Ahana , Amans Tiwangye , Fomena-Tchinda Hermann , Banaon Pinisikin Yasmina , Gina Ciniso Sizwe , Vuai Hidayat Ame , Farah Abdikadir Mohamud , Niang Adji Billo , Taicha Abdelhak , Ahmed Seifeldin , Bashir Ahmed , Abdelbaki Chérifa , Mwamila Tulinave Burton , Gwenzi Willis , Nya Esther Laurentine , Noubactep Chicgoua
Published: February 2024

Rainwater harvesting (RWH) is principally based on collecting, storing, and using rainfall which would otherwise be lost as surface runoff. Runoff threatens in several ways: accelerating erosion, intensifying flooding, and reducing groundwater recharge. Therefore, purposely retaining rainfall in the urban water cycle rather than draining has several positive impacts on designing sustainable cities. This work presents a proposal on how to avoid flooding in cities by systematically harvesting, storing rainwater, and using it for multiple purposes. The concept of RWH presented here has the potential to be a radical innovation to solve the social, economic, and environmental challenges associated with flash flooding. Each residence is regarded as a water production unit. Depending on the climatic conditions, people can meet their water needs on a local household basis, or alternatively use piped water as a complement. By infiltrating rainwater, groundwater is locally recharged and downstream wells are more productive. The implementation of this idea involves entrepreneurial agency that challenges existing structures, rather than adapting to them. Clearly, social entrepreneurship and social innovation are expected to catalyse the realization of this social innovation, also in rural areas. It is about mobilizing ideas, capacities, and resources to create a sustainable social transformation.
Devices for Filtering and Spectral Analysis of Radio Signals in Radio Engineering Information Systems
Authors: ZAICHENKO Kirill V. , GULYAEV Yuri V.
Published: February 2024

The widespread use of multi-channel systems and signal processing methods is the
development trend of modern radio engineering information systems. The case examples are
multi-channel filtering and spectral analysis devices, which are discussed in detail in this
monograph. Exceptional opportunities for improving methods and devices for information
processing emerge from the use of information and, in particular, structural redundancy that
appears as a result of the multi-channel processing of radio signals with a high-frequency
resolution. This has resulted prominently in recent years. Solving the problems of study, design,
and implementation of spectral analysis tools on acoustic waves are the most important tasks
of applying the latest achievements in the development of technologies, methods, algorithms,
structures, and devices for radio signals spectral processing in modern multifunctional multichannel radio information systems.
Synthesis of Algorithms and Structures for Frequency Measuring of Radio Signals at the Output of Filtering and Spectral Analysis Devices
Authors: ZAICHENKO Kirill V. , GULYAEV Yuri V.
Published: February 2024

When studying the problems of spectral processing of radio signals, implementing
their technologies, methods and algorithms for analysis, modeling, and development of
structures and devices for filtering and spectral analysis, the final goal is, generally, frequency
selection and frequency measurement of radio signals. A set of issues related to such
measurements is considered. Algorithms, structures, and devices for measuring the frequency
of radio signals after their spectral processing have been developed.
Performance and Implementation of Frequency Measuring Equipment for Radio Signals
Authors: ZAICHENKO Kirill V. , GULYAEV Yuri V.
Published: February 2024

A review of methods for estimating signal parameters and the synthesis of devices
for estimating and measuring their frequency showed that there are a large number of different
options for constructing frequency discriminators. On this basis, open and tracking meters can
be implemented on various elements. Each of them brings its own specifics to the processing
of radio signals in the frequency measurement channels. Such a variety of measuring elements
and structures prescribes different approaches to their research, but only relatively simple
devices can be analyzed analytically, although most often under significant restrictive
assumptions. Others, more complex and with less stringent constraints, can be studied through
computer modeling or hybrid modeling approaches. The ultimate and most preferred method
for analyzing the accuracy of frequency discriminators and meters based on them should be
considered an experimental study in laboratory or natural conditions, which allows obtaining
the most reliable and valuable results.
Filtering of Microwave Signals for Satellite Communication Systems
Authors: KOMAROV Vyacheslav V. , MESHCHANOV Valery P.
Published: February 2024

High electrical strength and low losses compared to other transmission lines
predetermined the widespread use of waveguide filters and multiplexers in on-board radioelectronic complexes of satellite communication systems. The electrical parameters of these
devices, taking into account the specifics of their operation in near-Earth orbit, are subject to
fairly stringent requirements: high power limit, temperature stability, weight, and size
indicators. Their disadvantages can be considered as a limited range of operating frequencies,
determined by the cutoff frequencies of the main and first higher modes, as well as relatively
large sizes. Very high requirements are also placed on the accuracy of the manufacture of
filtration devices. At present, in the literature, one can find a description of a large number of
various designs of band-pass filters of the waveguide type. Some of them are considered in the
present chapter.
Microstrip Filters on Co-directional Hairpin Resonators with Split Poles of Operating Attenuation
Authors: ARISTARKHOV Grigory M.
Published: February 2024

Circuit engineering methods for increasing frequency selectivity of microstrip filters
based on half-wave co-directional hairpin resonators are studied, the principle of operation
which is based on the rational use of the effect of inequality of normal wave phase velocities.
It is shown that in these structures with N resonators, it is possible to form N + 1 operating
attenuation poles at finite frequencies without introducing additional electromagnetic couplings
between non-adjacent resonators. The conditions for splitting the operating attenuation poles in
compact multiply coupled structures are determined. The results of experimental studies of this
type of highly selective filter are presented.
Single- and Dual-resonator Structures with the Properties of Multi-Resonator Microwave Networks
Authors: ARISTARKHOV Grigory M.
Published: February 2024

In the structures considered in the previous chapter, a limited number of operating
attenuation poles (transmission zeros) P ≤ N + 1 is formed, which is a limiting factor for a
further increase of filter selectivity using resonators with a relatively low intrinsic Q factor.
This is due to the structural construction of these circuits and, as it seems to us, an insufficient
number of degrees of freedom in the independent control of the frequency properties of partial
two-pole impedances Za and Zb of their equivalent circuits. This chapter explores new properties
of single- and dual-resonator MSF structures, in which up to six or more operating attenuation
poles can be directly formed at finite frequencies, i.e., these structures with an extremely
minimal number of resonators sometimes demonstrate the properties of multi-resonator
microwave circuits.
Features of Multi-resonator Microstrip Filter Design Using Highly Selective Elements
Authors: ARISTARKHOV Grigory M.
Published: February 2024

The principles of constructing high-order microstrip filters based on single- and dualresonator highly selective sections are being developed. It is shown that a significant increase
of microstrip structure selectivity with a minimum number of resonators can be achieved by
using the method of "reverting" of the transmission zeros, the effect of combining the main and
parasitic passbands, as well as the galvanic connection of the sections instead of their cascade
connection.
Clinical Decision Support System Used in Spinal Disorders: Scoping Review
Authors: Toh Zheng An , Berg Bjørnar , Han Qin Yun Claudia , Hey Hwee Weng Dennis , Pikkarainen Minna , Grotle Margreth , He Hong-Gu
Published: February 2024

Background

Spinal disorders are highly prevalent worldwide with high socioeconomic costs. This cost is associated with the demand for treatment and productivity loss, prompting the exploration of technologies to improve patient outcomes. Clinical decision support systems (CDSSs) are computerized systems that are increasingly used to facilitate safe and efficient health care. Their applications range in depth and can be found across health care specialties.

Objective

This scoping review aims to explore the use of CDSSs in patients with spinal disorders.

Methods

We used the Joanna Briggs Institute methodological guidance for this scoping review and reported according to the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) statement. Databases, including PubMed, Embase, Cochrane, CINAHL, Web of Science, Scopus, ProQuest, and PsycINFO, were searched from inception until October 11, 2022. The included studies examined the use of digitalized CDSSs in patients with spinal disorders.

Results

A total of 4 major CDSS functions were identified from 31 studies: preventing unnecessary imaging (n=8, 26%), aiding diagnosis (n=6, 19%), aiding prognosis (n=11, 35%), and recommending treatment options (n=6, 20%). Most studies used the knowledge-based system. Logistic regression was the most commonly used method, followed by decision tree algorithms. The use of CDSSs to aid in the management of spinal disorders was generally accepted over the threat to physicians’ clinical decision-making autonomy.

Conclusions

Although the effectiveness was frequently evaluated by examining the agreement between the decisions made by the CDSSs and the health care providers, comparing the CDSS recommendations with actual clinical outcomes would be preferable. In addition, future studies on CDSS development should focus on system integration, considering end user’s needs and preferences, and external validation and impact studies to assess effectiveness and generalizability.

Trial Registration

OSF Registries osf.io/dyz3f; https://osf.io/dyz3f
Federalism and the Notwithstanding Clause
Authors: Mathen Carissima
Published: February 2024

This paper looks at possible responses to section 33 that could deeply affect the country’s underlying federal structure. It discusses three responses — disallowance, judicial review, and formal constitutional amendment — that have either arisen in public discourse or, I argue, warrant serious consideration. The ultimate goal of the paper is to offer a more complex way of thinking of about section 33 focusing on its relationship to Canadian federalism and, by implication, to the future course of the country’s democratic constitutionalism.
ASSESSMENTOFTHERMALPAINSENSITIVITYVALUESIN PATIENTS WITH CONSEQUENCES OF THORACOLUMBAR SPINE INJURY
Authors:   Federal State Budgetary Institution National Ilizarov Medical Research Centre for Traumatology and Orthopedics of the RF Ministry of Health, Shchurova Elena N. , Kachesova Anastasiia A. ,   Federal State Budgetary Institution National Ilizarov Medical Research Centre for Traumatology and Orthopedics of the RF Ministry of Health, Prudnikova Oksana G. ,   Federal State Budgetary Institution National Ilizarov Medical Research Centre for Traumatology and Orthopedics of the RF Ministry of Health
Published: February 2024

Studying the sensitive sphere is not unimportant in determining the degree of injuring the spinal cord and its structures, the nervous system plasticity, and the processes of recovering after injury.However, little attention has been paid in the literature to the instrumental assessment of sensitivity in patients with the consequences of the thoracolumbar spine injury. Purpose of the Work. To study the features of the state of thermal pain sensitivity in patients with long-term consequences of the thoracolumbar spine injury with partial damage to the spinal cord and its structures (type B and C according to ASIA scale). Material and Мethods. A total of 22 patients with long-term consequences of the spinal cord injury in the thoracolumbar spine (type B and C, ASIA) was examined.Clinical analysis of sensory disorders was carried out according to ISNCSCI and ASIA scales. An electric esthesiometer was used to study thermal pain sensitivity in Th10-S2 dermatomes on the right and left. Results. Regardless of the type of injuries (B/C), the similar disorders were determined: hypoesthesia of thermal pain sensitivity; hyperesthesia of pain sensitivity; thermanesthesia; thermanalgesia. However, the degree and level of disordering varied. In the group of patients with type B, significant changes in thermal pain sensitivity were recorded from L1dermatome,in patients with type C – from L4. In the group of patients with type C, in comparison with the values of patients with type B, there was a decrease in the number of cases of thermanesthesia (by 38%, p=0.033) and thermanalgesia (by 64.3%, p=0.004), an increase in the proportion of dermatomes with normal pain sensitivity thresholds (by 443%, p =0.036) and with hypoesthesia of thermal sensitivity (by 52%, p=0.037). Conclusion. In patients with long-term consequences of the thoracolumbar spine injury the level of significant disorders of thermal pain sensitivity depends on the degree of traumatization of the spinal cord. In the group of patients with type B, significant changes in temperature and pain sensitivity are recorded from the dermatome L1, in patients with type C — from L4.
THE VALUE OF MUTATIONS IN THE ASXL1 GENE IN THE ONCOGENESIS OF ACUTE MYELOID LEUKEMIA IN ADULTS
Authors:   State Autonomous Healthcare Institution of the Sverdlovsk Region ", Vinogradov Alexander V. ,   Sverdlovsk Regional Clinical Hospital No. 1",   , Department of Hematology, Chemotherapy and Bone Marrow Transplantation, Sazonov Sergey V. ,   State Autonomous Healthcare Institution of the Sverdlovsk Region “Center for Specialized Types of Medical Care “Institute of Medical Cell Technologies”
Published: February 2024

The aim was to evaluate the significance of the ASXL1 gene mutations in the oncogenesis of acute myeloid leukemia (AML) in adults. Materials and methods. Bone marrow and peripheral blood samples of 49 patients with AML aged from 18 to 84 years, treated at the Sverdlovsk regional hematological center, were examined, including those with a morphological variant of AML M0 – 3, M1 – 4, M2 – 19, M3 – 6, M4 – 10, M5 – 1, M6 – 1, M7 – 1, blast plasmacytoid dendritic cell neoplasm – 1, acute hybrid leukemia – 2, AML after chronic myeloproliferative disease (CMPD) – 2. Mutations in the ASXL1 gene were detected in peripheral blood and bone marrow samples by direct RNA sequencing (n=26) and high-throughput DNA sequencing (n=23) on automatic genetic analyzers ABI Prism 310 and MiSeqDX, respectively. Results. It was found that pathogenetically significant mutations of the ASXL1 gene were detected in 16.3% of samples with AML M0, M2, M4, AML from CMPD and acute hybrid leukemia. The distribution of ASXL1 anomalies was as follows: deletion n. Del (1755;2007) — 4, duplication c.1934dupG — 3, non-synonymous transversion c.1348A>T — 1. Along with lesions of the ASXL1 gene, quantitative and structural chromosomal aberrations were determined in these samples, including del(5)(q13), t(8;21)(q22;q22), t(9;22)(q34;q11), as well as point mutations in the CEBPA, IDH2, NRAS, RUNX1, SRSF2, TET2 genes, internal tandem duplication in the FLT3 gene. This indicates the cooperation of two or more mutational events in the oncogenesis of ASXL1-positive AML, which can determine the different reaction of the tumor to chemotherapeutic treatment and the prognosis of the disease.
THE INFLUENCE OF THE KETONE DIET ON THE LEUKOCYTE FORMULA, STABILITY AND ACTIVITY OF THE GENETIC MATERIAL OF MICE
Authors:   Federal State Budgetary Educational Institution of Higher Education ", Kalaeva Elena A. ,   Voronezh State University", Kalaev Vladislav N. ,   Federal State Budgetary Educational Institution of Higher Education "Voronezh State University", Blazhenov Igor V. ,   Federal State Budgetary Educational Institution of Higher Education "Voronezh State University", Nechaeva Marina S. ,   Federal State Budgetary Educational Institution of Higher Education "N.N. Burdenko Voronezh State Medical University" of the Ministry of Healthcare of the Russian Federation, Maltseva Oksana Yu. ,   Federal State Budget Educational Institution of Higher Education "Voronezh State University of Engineering Technologies", Novikova Inna V. ,   Federal State Budget Educational Institution of Higher Education "Voronezh State University of Engineering Technologies"
Published: February 2024

The effect of a 14-day ketogenic diet on the level of erythrocytes with micronuclei, the activity of nucleolar-forming regions in lymphocytes, and the leukocyte blood count of 8-week-old male C57BL/6 mice was studied. It was found that in animals receiving a ketone diet, the proportion of erythrocytes with Jolly bodies was 18.7 times higher than in mice in the control group receiving a standard diet. The diet did not cause changes in nucleolar activity in lymphocytic cells of the peripheral blood of experimental animals. A slight increase in the level of neutrophils in mice from the experimental group compared with the control was found, probably induced by a change in the biochemical composition of the blood (ketodiet mimics the state after fasting or heavy exercise, which may be accompanied by slight neutrophilia). A significant increase in the proportion of erythrocytes with micronuclei in the peripheral blood of animals of the experimental group may be due to a violation of cell maturation under conditions of severe deficiency of the main energy source for red blood cells — glucose and the inability to use ketone bodies as an energy substrate.
AVAILABLE OPTIONS FOR HCV INFECTION TREATMENT IN DECOMPENSATED LIVER CIRRHOSIS PATIENTS
Authors:   State Autonomous Health Care Institution ", Anashkina Maria A. ,   Sverdlovsk Regional Clinical Hospital №1", Bessonova Elena N. ,   State Autonomous Health Care Institution "Sverdlovsk Regional Clinical Hospital №1", Klimusheva Natalia F. ,   State Autonomous Health Care Institution "Sverdlovsk Regional Clinical Hospital №1", Bazarnyi Vladimir V. ,   Federal State Budgetary Educational Institution of Higher Education Ural State Medical University of the Ministry of Health of the Russian Federation
Published: February 2024

Introduction. Chronic viral hepatitis C is an infectious disease that is widespread among the working-age population and is often diagnosed at liver cirrhosis stage. The opportunity to slow down the progress of infection and subsequent complications appeared when the drugs with direct antiviral action became wildly available. However, the problem of antiviral treatment decompensated liver cirrhosis patients (Child-Pugh classes B and C) is still controversial and discussed. This category of patients is still the most difficult to treat. Research objectives. Search for a comprehension of the optimal liver function for the safe administration of DAA, determination of the optimal timing and DAA regimen for patients with decompensated cirrhosis based on a review of the literature. Methods. The source of information was PubMed medical bibliographic databases, from which 26 original articles for 2015–2021 were selected. Conclusion. Relatively small number of patients with cirrhosis Child-Pugh C, the high incidence of adverse events and decompensations, and the absence of clearly defined criteria for prescribing DAA, this problem requires further study and research.
THE EFFECT OF SUNLIGHT ON HUMAN HEALTH
Authors:   Federal State Budgetary Educational Institution of Higher Education ", Boldyreva Yulia V. ,   Tyumen State Medical University",   of the Ministry of Health of the Russian Federation, Gubin Denis G. ,   Federal State Budgetary Educational Institution of Higher Education "Tyumen State Medical University" of the Ministry of Health of the Russian Federation
Published: February 2024

Introduction. Light is electromagnetic radiation, which plays a huge role in the life of each of us, because it supplies the body with most of the information about the world around it and influences the course of many biochemical processes. However, sunlight, like any effect on the body, can have both beneficial and negative effects. In this connection, updating and systematizing the available data on the research topic is an important problem at the present time.Results and discussions. Under the influence of sunlight, first of all, the active form of vitamin D is formed in the body. Along with this, biologically active compounds are synthesized, in particular, nitric oxide (I). These compounds prevent the development of a number of socially significant diseases, for example, metabolic syndrome, Alzheimer’s disease, etc. Conclusion. The beneficial effect of sunlight on human health has been proven, thanks to vitamin D. Along with this, biologically active supplements containing vitamin D do not give similar results.
From the Soil to the Screen: Women Representation in Contemporary Rural China
Authors: Chen Oscar
Published: February 2024

This research delves into the representation of female characters in contemporary Chinese cinema, focusing on films set in rural and underdeveloped areas between 2010 and 2022. Under the guidance of Professor Luis Duno Gottberg at Rice University, the study scrutinizes the complex interplay between traditional socio-cultural norms and evolving gender perceptions within these cinematic narratives. Central to our inquiry is the exploration of how a distinctly Chinese interpretation of the Male Gaze and entrenched Confucian patriarchal values shape the portrayal of women, signaling a negotiation between historical and cultural influences and modern identities. Employing a qualitative research methodology, this study integrates a comprehensive literature review, focusing on feminist film theory and its application within the Chinese context. Content analysis of selected films is conducted to uncover recurring visual and narrative themes, character development, and gender dynamics.
Literature and Mythology: Exploring Mythological Elements and Archetypes in “The Lion, the Witch and the Wardrobe”
Authors: Raj Greeshma
Published: February 2024

This article delves into the intricate relationship between literature and mythology, exploring how C.S. Lewis skilfully intertwines mythological elements and archetypes in his classic children's book, "The Lion, the Witch, and the Wardrobe." The author examines the use of Christian symbolism, the resurrection motif, and characters inspired by traditional myths to create a timeless narrative. The essay explores the subversion of myths within the story, emphasizing the nuanced characterization of figures like the White Witch and the unexpected transformation of flawed heroes. Additionally, the article analyses the thematic implications and character development in the novel, highlighting the central themes of good vs. evil, redemption, sacrifice, heroism, and friendship. Furthermore, it discusses how Lewis subtly subverts mythological elements, challenging preconceptions and providing a fresh perspective on timeless tropes. The Narnian setting itself is examined, with its disruption of time and diverse array of magical creatures challenging conventional expectations. In conclusion, the article asserts that "The Lion, the Witch, and the Wardrobe" stands as a testament to the enduring impact of the legendary genre on fiction, showcasing Lewis's ability to transform familiar myths into a thought-provoking and timeless masterpiece.
Resistance and Resilience: A Critical Study of Bama’s Vanmam
Authors: Mani B. Vivilia Arivu
Published: February 2024

This paper aims to analyze how Dalit women are portrayed in literature in Bama's Vanmam. The current study looked specifically at how caste and gender interact in Vanmam, with an emphasis on how Dalit women are portrayed there. The second half of the 20th century saw a thriving output of Tamil-language works by Dalit writers, who are thought to have explored the writers' responses to issues related to the Dalit community's caste identity and its interaction with a gendered social matrix. The book being studied depicts a ten-year proactive involvement in Tamil literary discourse that gave rise to a fresh, lively voice that challenged literary and cultural clichés, establishing new benchmarks and novel perspectives on literary frameworks. Dalit women are depicted as continuously weeping, wailing, wishing for male protection, cursing their femininity, and lamenting their incapacity to maintain their chastity on their own. Instead of being portrayed as fighters like in Bama's novels, they are shown as victims. Dalit women are victims of sexual violence.
Harassment and Perseverance for oneself in Usha Ganguly’s Rudali
Authors: Sriee M. Sruthi
Published: February 2024

This paper aims to analyse how a woman belonging to a low society is abused and how she stands for herself in Usha Ganguly’s Rudali. The paper depicts specifically at how caste and poverty reflect the differences in the interaction between the high and the low sections of a society. Women belonging to lower community are depicted as continuously weeping, wailing, cursing their femininity and being responsible despite all the odds. The play written by Usha Ganguly depicts the fate of the female protagonist Sanichari, who is being harassed through harsh words and curses used by her family members due to a vague entitlement given for her name and her birth on an inauspicious day. Being cursed, abused through harsh words and completely isolated, she decides to become a Rudali (Mourner).
Temperature Dependent Dielectric Properties Using Reflectrometric Technique of (Drumstick) Moringa oleifera Lam.
Authors: Karhale Dr. Govind A.
Published: February 2024

Abstract: The use of dielectric properties of agricultural products for sensing moisture in seeds and their powder form and their applications in microwave dielectric heating are discussed briefly. Values of dielectric properties of products in powder form are presented in tables and graphically to show the dependence of these properties on frequency, moisture content, and temperrature. Use of dielectric properties of Moringa oleifera Lam. For moisture measurement has been most prominent agricultural applications for such data. The results show that, there was a systematic increase in dielectric constant (ε') and loss factor (ε") with increasing values of relative packing fraction (δr) and decrease in dielectric constant and loss factor with increasing temperature. The moisture percentage measured by Thermo -gravimetric method. Experimental results of different relative packing fractions were further used to obtain transformation to 100% solid bulk using correlation equations of Landau-Lifshitz- Looyenga and Bottcher. The result shows that, there is a fair agreement between experimental values and theoretical values of different dielectric parameters.
Microensilados de pasto elefante BRS Capiaçu adicionados con consorcio microbiano comercial en diferentes días de rebrote
Authors: Da Silva Santos Allan Stênio , Da Costa Araújo Daniel Louçana , Rodrigues da Silva Ivone , Sousa Araújo Matheus , Azevêdo Alves Arnaud , Nunes Parente Henrique , De Oliveira Maria Elizabete , Batista Lopes João
Published: February 2024

Este estudio tuvo como objetivo evaluar si la inoculación bacteriana mejora las características fermentativas, microbiológicas y químicas de los ensilados del pasto elefante cv. BRS Capiaçu en diferentes días de rebrote. El diseño experimental fue completamente al azar y se estableció en un arreglo factorial 3x2 (tres días de rebrote, con y sin inoculante), con cuatro repeticiones. Hubo una interacción significativa entre los días de rebrote y el inoculante sobre el pH, el nitrógeno amoniacal (N-NH3) y las pérdidas por efluentes (PE) de los ensilados. La inoculación disminuyó la PE con el avance de los días de rebrote y aumentó la tasa de recuperación de materia seca en comparación con los ensilados sin inoculante. La población de mohos y levaduras disminuyó cuando se adoptó la inoculación al forraje cosechado después de 85 d. Hubo una interacción significativa entre la materia seca (MS), la proteína cruda (PC) y la fibra detergente neutro corregida por los contenidos de cenizas y proteína (FDNcp) de los ensilados. La inoculación en el pasto cosechado después de 85 días aumentó el contenido de MS del ensilado. Los mayores contenidos de PC se observaron en los ensilados después de 85 días. Los contenidos de FDNcp de los pastos cosechados después de 110 y 135 días fueron mayores que el del pasto cosechado después de 85 días. El contenido de FDNcp de los ensilados sin inoculante aumentó con la edad de cosecha. El ensilado de forraje de BRS Capiaçu cosechado a los 110 días demostró un desempeño favorable para la producción de ensilado. Sin embargo, la influencia del uso de inoculantes fue baja para las características evaluadas.
Pembuatan Bolu Gulung Menggunakan Campuran Tepung Kacang Merah
Authors: Aditya I Komang Arta , Aprinica Ni Putu Isha
Published: February 2024

Bolu gulung adalah produk makanan yang terbuat dari tepung terigu, gula, lemak dan telur. Pembuatan Bolu membutuhkan pengembangan gluten dan biasanya digunakan bahan pengembang kimiawi. Tujuan dari penelitian ini adalah untuk mengetahui kualitas Bolu Gulung dengan subtitusi campuran tepung terigu dengan tepung kacang merah. Teknik analisi data yang digunakan adalah analisis data deskriptif kuantitatif uji organoleptik, uji daya tahan dan analisis biaya. Berdasarkan uji organoleptik, penelitian ini dinilai oleh 25 panelis, uji daya tahan produk dilakukan selama 9 hari dan menghitung analisis biaya yang diperlukan. Dari segi rasa, aroma, warna, tekstur, Pembuatan Bolu Gulung Menggunakan Campuran Tepung Kacang Merah P3 (75%) memiliki kualitas yang unggul dibandingkan P1 (25%) dan P2 (50%). Dari uji daya tahan Pembuatan Bolu Gulung Menggunakan Campuran Tepung Kacang Merah P3 (75%) bertahan 9 hari di suhu ruangan terbuka. Simpulan dari penelitian ini, hasil terbaik adalah Pembuatan Bolu Gulung Menggunakan Campuran Tepung Kacang Merah dengan substitusi 75%.
 
Roll sponge cake is a food product made from wheat flour, sugar, fat and eggs. Sponge making requires the development of gluten and usually a chemical developer is used. The purpose of this study was to determine the quality of Sponge Rolls by substituting a mixture of wheat flour with red bean flour. The data analysis technique used is descriptive quantitative data analysis of organoleptic test, endurance test and cost analysis. Based on the organoleptic test, this study was assessed by 25 panelists, the product durability test was carried out for 9 days and calculated the required cost analysis. In terms of taste, aroma, color, texture, Making Sponge Rolls Using a Mix of Red Bean Flour P3 (75%) has superior quality compared to P1 (25%) and P2 (50%). From the durability test of Making Sponge Rolls Using a Mix of Red Bean Flour P3 (75%) it lasted 9 days at open room temperature. The conclusion of this research, the best result is Making Sponge Rolls Using Mixed Red Bean Flour with 75% substitution.
Teologi Perdamaian dan Kerukunan Antar Agama dalam Perspektif Asghar Ali Engineer
Authors: Saumantri Theguh
Published: February 2024

This article explores the concept of Islamic theology of peace and interfaith harmony through the perspective of Asghar Ali Engineer, particularly focusing on the essence of Islam, theology of peace, and interreligious harmony. The article employs a literature study method, analyzing and interpreting Engineer's works. Asghar Ali Engineer, an Indian Muslim scholar and intellectual, advocates for peace and pluralism in Islam, emphasizing the importance of Tauhid (the Oneness of God) as a foundation for social justice and peace. His approach integrates the concept of liberation theology, emphasizing the necessity of liberating humanity from oppression and injustice. Engineer interprets Tauhid not merely as a religious ritual but as a social structure that fosters equality and peace. He argues that true peace in Islam involves respecting religious diversity and eliminating coercion in faith. The study affirms that Engineer's theology of peace is relevant in multicultural and multireligious contexts like Indonesia and can offer an alternative approach to resolving interfaith conflicts. Engineer's emphasis on dialogue and understanding among different faiths is crucial for enhancing harmony and reducing societal polarization.AbstrakArtikel ini mengeksplorasi konsep teologi perdamaian Islam dan kerukunan antaragama melalui pemikiran Asghar Ali Engineer, khususnya mengenai esensi Islam, teologi perdamaian, dan kerukunan antar agama. Artikel ini menggunakan metode studi pustaka dengan menganalisis karya-karya Engineer dan menginterpretasikannya. Asghar Ali Engineer, seorang ulama dan intelektual Muslim India, mengadvokasi perdamaian dan pluralisme dalam Islam, menekankan pentingnya Tauhid (Keesaan Allah) sebagai dasar untuk keadilan sosial dan perdamaian. Pendekatannya menggabungkan konsep teologi pembebasan, menekankan pentingnya membebaskan umat manusia dari penindasan dan ketidakadilan. Engineer menafsirkan Tauhid tidak hanya sebagai ritual agama tetapi sebagai struktur sosial yang mendorong kesetaraan dan perdamaian. Ia berargumen bahwa perdamaian sejati dalam Islam melibatkan penghormatan terhadap keragaman agama dan penghapusan paksaan dalam beragama. Kajian ini menegaskan  bahwa teologi perdamaian Engineer relevan dalam konteks multikultural dan multireligius seperti di Indonesia dan dapat menjadi pendekatan alternatif untuk mengatasi konflik antar agama. Penekanan Engineer pada dialog dan pemahaman antar agama yang berbeda sangat penting untuk meningkatkan kerukunan dan mengurangi polarisasi masyarakat.