bluuebunny/crossref_metadata_2025 huggingface dataset:
Agriculture Data Analytics in Crop Yield Estimation using IBM Cognos
Authors: T Dr. Gururaj
Published: July 2022

Abstract: Analytics is the interpretation of data pattern that assist decision- making and performance improvement. Agriculture Data analytics in crop yield helps in analysing some important visualization, creating a dashboard and by going through these we will get most of the insights of Crop production in India. IBM Cognos Analytics integrates reporting, modelling, analysis, exploration, dashboards, stories, and event management so we can understand our organization's data, and make effective decisions. A dashboard helps us to monitor events or activities at a glance by providing key insights and analysis about our data on one or more pages or screens. In this project, we visualize, analyse and gain most of the insights by creating a dashboard.
Health Information Exchange using BlockChain and Cardiac Disease Prediction using Naïve Bayes Algorithm
Authors: Siddique Sumaiya
Published: July 2022

Abstract: The interchange of electronic health data across healthcare facilities is made possible via the health information exchange program. There is a potential for data manipulation in this. This article primarily focuses on using "Blockchain," i.e. one of the greatest technologies, to secure medical health data. Blockchain has demonstrated its outstanding qualities in the field of cryptocurrencies like bitcoin and Ethereum. This study employs the Secure Hash Algorithm (SHA), Simple Mail Transfer Protocol (SMTP), and AES Rijndael Algorithm (SMTP). Additionally, using the Naïve Bayes method, we forecast many heart illnesses related to this work.
Cost and Quality Analysis of Bio-Deposited Recycled Aggregates Concrete
Authors: Chatterjee Anik
Published: July 2022

Abstract: Internationally, the utilization of concrete particularly high-strength concrete has been increasing day-by-day due to rapid industrialization and infrastructural developments. An enormous quantity of natural coarse aggregate is required for making concrete to meet the huge demand. Construction activities mainly depend on natural resources as a source of raw materials, leading to ecological imbalance & the natural resources of coarse aggregate are depleting rapidly all over the world and urgently need to be conserved. On the other hand, millions of tonnes of construction and demolition (C&D) wastes are being generated from different sources. So far the disposal of these huge quantity of (C&D) waste is posing a big problem to the local administration & environment. In this study, recycled aggregates were collected from a 20-30 year old demolished building at the university and recycled into fractions of 1.20 mm~2.45mm and 10 mm~20 mm and replaced for both fine aggregates and coarse aggregates. In this study, by surface treatments on coarse fractions of recycled aggregates were treated by microbes, and the properties of the RAC were studied with the combination of both surface-treated recycled coarse aggregates and un-treated recycled fine aggregates.
An Application for Monitoring Pregnant Women Using IOT
Authors: R M Ankitha
Published: July 2022

Abstract: Pregnancy is a special condition in which women go through various health complications throughout the period of gestation. It is not feasible to predict those complications in an absolute manner. Delays in diagnosis or in the initiation of treatment contribute to a large portion of pregnancy related deaths. The System is capable of distinguishing abnormal readings of patient as a known medical complication specific to pregnancy which is available to end user.
Baby Monitoring Robot Using IoT
Authors: B R Ajay Kumar
Published: July 2022

Abstract: In order to help parents who are already stretched thin, this project offers a mechanism for monitoring infants. The baby's movements and sound can be detected by this system, notably crying, and a video output of the baby's current position can be shown on a display monitor so that the mother or another responsible adult can keep an eye on the child while they are away. The motion and crying of the infant can be automatically detected by this baby monitoring device. The voice recognition module, motion sensor, and camera are all integrated into the Arduino nano module to create the hardware's overall control system. A motion sensor is also used to detect the baby's movement. The hardware devices are operated using the Arduino IDE. Baby videos that are either sleeping or playing are displayed on a display. Last but not the least, the developed hardware is evaluated to determine its capacity for detecting the baby's motion and cries as well as the video output.
The Impact of Data Breach on Reputed Companies
Authors: Ray Rakesh Kumar
Published: July 2022

Abstract: We'll come to digital India we the Indians are at the top position in internet usage at the same time India is ranked third among list of countries globally where most of the threats were detected &second globally when it comes to spam and phishing (misleading emails, weblink etc. A data breach is the planned or inadvertent disclosure of confidential information to unauthorized parties. The impact of cyber-attack on a Company is much higherthan the impact on an individual.Data leakage poses serious threats to companies, including significant reputational damage and financial losses. Day by day as the volume of data is growing exponentially and data breaches are happening more frequently than ever before, identifying and preventing data loss has become one of the most pressing security concerns for organizations. This review article helps to learn about company’s data leak threats, recent data breach incidents and its impact on reputed companies
Android Application for Finding Local Jobs
Authors: Shetty Rishab
Published: July 2022

Abstract: The development of Technology has prompted a reality where everybody is associated just by means of PCs, cell phones and tablets. Subsequently has caused world to appear to be more modest. That one creation that rolled out an extraordinary improvement in the loves of individuals are PDAs. The variable that makes cell phone a savvy gadget are portable applications. Different applications fill different needs as per the need. Inspite of extensive variety of utilization accessible, not many areas actually need utilizing this innovation. One such areas is opportunity in requests for employment of limited scope industry. The conventional approach to advising position in these areas are through news papers or releases. Consequently this, project points planning an application for the gig searchers and suppliers of the limited scale industry. Another area that need are local area level association's. As people group develops keeping up with the record of the individuals gets dreary. At present little local area keep up with records of their individuals like individual informations, phone records, and so on mannually in a register. Every one of these data could be only a tick away when put togther in one application. This undertaking points in planning one such application.
Correlation of ECG Values to the Behavior of Heart Attack Sufferers
Authors: B Chaithra , Sumana K R , Phaneendra Dr. H D
Published: July 2022

Abstract: Heart attack is among one of the deadliest of cardiovascular diseases. It happens as circulation or blood flow to heart muscle is interrupted, causing the heart muscle to damage or die. The essential reason for most heart assaults could be a blockage which causes blood stream to one of the coronary courses, imperative channels through which blood voyages to the heart muscle, to become reduced or obstructed. When blood stream is discouraged or decreased, the heart muscle is quickly denied of ruddy blood cells which carry the fundamental oxygen basic for supporting life and awareness in the human body. It takes as few as six to eight minutes without oxygen to cause the heart muscle to capture, driving to the individual’s passing. And the cause of most heart attacks is plaque, a hard substance which builds up over time in the coronary arteries. Plaque, a substance made up of numerous cells and cholesterol (fat), draws platelets, etc., which increase over time, causing a blockage large enough to diminish or block blood flow to heart muscle. Cardiac disease medications are regularly being subjected to the securing and investigation of tremendous amount of advanced cardiac information. The objective of the project is to make the analysis on the digital ECG dataset is made on the various medical terminologies that correlates towards Heart Attack. To implement a Deep Learning Model that correlates what digital ECG values maps to the abnormal patterns which leads to Heart Attack. To analysis further on gender, age group and lifestyle of a Heart Attack Patients.
Heart Disease Prediction Using Machine Learning Technique
Authors: K Dr. Hareesh , N Ganesh , V P Chetan Kumar , Naik Pavan , M Gowtham
Published: July 2022

Abstract: Heart sickness has been a significant dangerous issue in a person. Because of a few reasons like dietary patterns, absence of activity, becoming overweight and smoking, and unfortunate way of life propensities cause heart sicknesses. This propels us to find out about the put factors in our life in extreme danger in regards to the reason for coronary illness. The proposed strategy recommends the degrees of chance elements agreeing with the patient's information, with the goal that one can deal with their wellbeing appropriately to forestall the coronary illness. In this examination work, the proposed procedure is to isolate coronary illness patients in light of their gamble factors. As a matter of some importance applying the half assurance is to diminish the records of knowledge and to line up the model speedier. The 5 classifiers area unit strategic relapse, support vector machine, K-closest neighbor, selection tree, and irregular backwoods area unit applied. beyond applying the classifiers, a projected model can disengage the coronary illness patients considering their bet factors in line with the Age of the patients. this may assist the consultants with researching the card-playing parts of the patients.
Galantamine: A Review Update
Authors: Kaur Jaspreet , Melkani Indu , Singh Ajeet Pal , Singh Amar Pal , Bala Kiran
Published: July 2022

Galantamine, like nor-belladine, is a benzazepine. Galanthus and other plants of the Amaryllidaceae are the most common sources of it. Galantamine is used to combat the muscle effects of gallamine triethiodide and tubocurarine by acting as a cholinesterase inhibitor. The review reveals the protective effects of galantamine on the functions and integrity of the liver, brain and memory impairment. Various independent studies have shown anti-Alzheimer, antioxidant, antidiabetic and neuroprotective effect of galantamine. The current review highlights current knowledge and the health-promoting effects of a drug known as galantamine. This review summarizes the current state in the pharmacology of galantamine, focusing on its effects on tolerance, dosage, drug interactions and pharmacological studies in animal models.

Keywords: Galantamine, Pharmacology, Acetylcholinesterase inhibitor, Neuroprotective, Protective effect.
Development and In-Vitro Evaluation of Plantago ovata Based Rapid Disintegrating Tablets of Labetalol Hydrochloride
Authors: Dubey Abhay Kumar , Archana ,
Published: July 2022

Objectives: To avoid swallowing problems of conventional tablets and improved patient compliance Plantago Ovata based Labetalol HCl Rapid disintegrating tablets have been prepared. Methods: Six different (F1 to F6) batches of Labetalol HCl Rapid disintegrating tablets were developed by ‘direct compression method’ using Plantago ovata as a natural super-disintegrating agent. The formulated RDT were tested for angle of repose’, densities like tapped and bulk density, Hausner’s ratio, Carr’s index like pre-compression parameters and for thickness, weight variation or weight uniformity, tablet hardness, % drug content or content uniformity, water absorption ratio’, time require for wetting of tablets’ means wetting time, in-vitro drug disintegration time and in-vitro drug dissolution studies under post-compression parameters of evaluation. Results: It was found that the all the results of these pre-compression and post-compression parameters comply with official standards. The drug release was determined using dissolution media of pH 6.8 phosphate buffer through in-vitro dissolution of drug. This study showed that a rapid drug release by prepared tablets. The optimized formulation F6 showed higher water absorption ratio`, lower wetting time, minimum in-vitro disintegration time’ and higher drug release amongst all the formulations. The F6 formulation was considered the best among all formulations. Conclusion: The prepared rapid disintegrating tablets shows rapid onset of action by quick drug release, minimize side effects and enhanced patient compliance. These prepared tablets containing selective alpha-1 and non-selective beta adrenergic antagonist’ drug candidate Labetalol HCl, will be very useful in the treatment of high blood pressure with enhanced bioavailability.

Keywords: Rapid disintegrating tablets, Labetalol Hydrochloride, Bioavailability Enhancement, Natural Superdisintegrant, Plantago Ovata, High Blood Pressure, RDT, Patient Compliance
Comparative Effects of Cashew Nut, Leaf and Stem Bark (Anacardium Occidentale L.) on Hyperglycemia and Associated Abnormalities in Streptozotocin-Induced Diabetic Rats
Authors: Ajao Folasade Omobolanle , Akanmu Oluwatosin , Iyedupe Marcus Olaoye
Published: July 2022

Background: Medicinal plants are used as alternative therapy for diabetes. This study investigated comparative effects of methanolic extracts of Anacardium occidentale (linn) nut, leaf and stem bark on hyperglycemia and associated abnormalities in streptozotocin-induced diabetic rats.

Methods: Ninety male Wistar albino rats weighing (200±20g) were used and diabetes was induced by single intraperitoneal injection of streptozotocin (50mg/kgb.wt). The rats were allotted into 9 groups, 10rats/group. Group I: (non-diabetic); Group II: (diabetic untreated); Groups: III & IV: diabetic rats received 100mg/kgb.wt& 200mg/kgb.wt nut extract; Groups: V & VI: diabetic rats received 100mg/kgb.wt& 200mg/kgb.wt leaves extract; VII & VIII were diabetic rats received 100mg/kgb.wt& 200mg/kgb.wt stem bark extract and Group IX: diabetic rats received 2mg/kgb.wt p.o glimepirides for 4weeks. Daily food and water intakes were recorded; weekly body weight and blood glucose levels were measured throughout the experiment. The animals were sacrificed on the last day and fasting plasma blood glucose was withdrawn for biochemical parameters estimation.

Results: Fasting plasma blood glucose, triglyceride (TG), total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C), aspartate aminotransferase (AST), alanine aminotransferase, alkaline (ALT), aminotransferase (ALP), urea, uric acid, creatinine, malondialdehydes (MDA) and water intake levels were significantly (p<0.01, 0.05) reduced in the extracts treated groups. However, High density lipoprotein- cholesterol (HDL-C), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH), body weight and food intake levels were significantly (p<0.01, 0.05) increased in the extracts treated groups.

Conclusion: Anacardium occidentale parts posses anti-diabetic properties. The nut has extreme therapeutic efficacy and could be used as alternative therapy for diabetes.

Keywords: Anacardium occidentale, Hyperglycemia, Lipid profiles, Antioxidants, Kidney function.
Holarrhena antidysenterica in Inflammatory Bowel Disease: a potential review
Authors: Bala Kiran , Melkani Indu , Singh Ajeet Pal , Singh Amar Pal , Kaur Jaspreet
Published: July 2022

Holarrhena antidysenterica belongs to the Apocynaceae family and is generally known as kurchi in Hindi. It is a small deciduous tree found in arid woods throughout the world including India. H. Antidysenterica is commonly used in Indian traditional medicine to treat Inflammatory Bowel disease, dysentery, diarrhoea and worms in the intestines.  Plant parts like bark are useful in antimicrobial, anti-inflammatory and analgesic treatments, amoebiasis, chronic bronchitis, boils, and ulcers. The Phytoconstituents   found in the plant ergosterol, flavonoids, phenolic acids, resins, saponins, steroidal alkaloids, coumarins, tannins and triterpenoids. Anti-amnesic, anti-diabetic, antibacterial action, anti-inflammatory, anti-diarrhoeal, antioxidant/free radical activity ,  radical scavenging, diuretic, anti-amoebic, anthelmintic and anti-microbial effects are found as pharmacological properties of Holarrhena  antidysenterica. H. antidysenterica bark contains alkaloids the most important of which is the steroidal alkaloid conessine which is the major therapeutic constituent. Conarrhimine, Conimine, Conamine, Conessidine, Isoconessimine, Dimethyl Conkurchine and Holarrhimine are among the various alkaloids studied. The bark also includes gum, resin, tannin, lupeol and the digitenol glycoside Holadysone in addition to alkaloids. Bark of Holarrhena antidysenterica is used to treat malaria, chest infections, asthma, bronchopneumonia, stomach disorders, dyspepsia, diarrhoea and dysentery.

Keywords: HA- Holarrhena antidysenterica, IBD- Inflammatory Bowel Disease, Collitus
Granulocyte colony stimulating factor (GCSF) protected in ovarian tissues against ischemia-reperfusion injury
Authors: Aktaş Ayfer , Aşır Fırat , Başaran Süreyya Özdemir , Kaplan Özge , Ermiş Işılay Sezen , Deveci Engin
Published: July 2022

Ovarian torsion is an important reproductive gynecological emergency in daily life and physiology. Granulocyte colony stimulating factor (G-CSF) is a glycoprotein capable of hematopoietic development and successfully used in the treatment of congenital granulocytopenia. In our study, we aimed to investigate protective effects of G-CSF on ovarian ischemia reperfusion (IR) immunohistochemically. Four groups were used. In control group, abdomen was opened and closed with the surgical protocol. The rats in the G-CSF group were given 100 µg/kg G-CSF subcutaneously before the IR and the abdomen was surgically opened and closed. 3-h of ischemia was and then 3-h reperfusion was induced in the ischemia-reperfusion (I/R) group. In the IR+G-CSF group, 100 µg/kg G-CSF was given before the procedure and IR was performed. At the end of the experiment, ovarian tissues were fixed in 10% formalin and then processed for routine paraffin tissue protocol. Normal ovarian histology was observed in the control and G-CSF groups. In the IR group, vascular dilatations, hemorrhage and increased inflammation were observed. In the I/R+G-CSF group, pathology in seen IR was decreased. IL-6 expression was mainly negative in control and G-CSF groups. Positive IL-6 immune reaction was observed in the granulosa cells and stromal area. In the I/R+G-CSF group, IL-6 expression was significantly decreased in ovarian follicular structures and in the stromal area compared to the I/R group. In conclusion, G-CSF reduced vascular dilatation and inflammation in the ovarian IR model and promoted ovarian folliculogenesis.

Keywords: Ovary, Ischemia/reperfusion, G-CSF, Azan, IL-6, Immunohistochemistry
Nanoparticle of Telmisartan and Polyvinylpyrrolidone K-30: Characterization and Dissolution Study
Authors: Fadhila Muthia , Wahyuni Rina , Sari Yeni Novita , Octavia Maria Dona , Lestari Meliati Dwi
Published: July 2022

Background: Telmisartan (TEL) is an orally active nonpeptide angiotensin II antagonist drug. The drug acts on a subtype of AT1 receptors, which serves to cope with high blood pressure (hypertension). TEL is a class II Biopharmaceutical Classification System (BCS), which is a drug that has low solubility in water and high permeability. Objectives: This study aims to determine the effect of the formation of TEL-PVP K-30 nanoparticles through the solvent drop grinding method on the characteristics of physicochemical properties and the rate of dissolution of TEL. Methods: Nanoparticles are made in 2 formulas, namely formula 1: 1 and formula 1: 2. Results: Characterization of the Particle Size Analyzer (PSA) was performed with the results of the formula 1:1 24nm, and the formula 1:2 35nm. X-ray Diffraction (XRD) analysis resulted from a decrease in the intensity of crystallinity degrees. Fourier Transform Infrared (FT-IR) Spectroscopy occurs wave number shift. Differential Scanning Calorimetry (DSC) decreases in melting point. The dissolution rate was carried out using a pH 7.5 phosphate tart medium. Conclusion: The result of the dissolution rate has increased by 3.3 times for formula 1:1 and 2.9 times for formula 1:2.

Keywords: Telmisartan; polyvinylpyrrolidone K-30; nanoparticles; and solvent drop grinding.
ANALISIS FISCAL POLICY TERHADAP PERTUMBUHAN EKONOMI DI PROVINSI ACEH
Authors: Murtala Murtala
Published: July 2022

Penelitian ini bertujuan untuk mengetahui pengaruh kebijakan fiskal dalam bentuk pajak dan belanja pegawai terhadap pertumbuhan ekonomi di Provinsi Aceh. Jenis data yang digunakan  adalah data sekunder dengan menggunakan variabel pajak, belanja pegawai dan pertumbuhan ekonomi dengan menggunakan model regresi. Hasil penelitian menunjukkan kebijakan fiskal dalam bentuk pajak berpengaruh negatif dan signifikan terhadap pertumbuhan ekonomi di Provinsi Aceh.  Kebijakan fiskal dalam bentukbelanja pegawai  berpengaruh negatif dan signifikan terhadap pertumbuhan ekonomi di Provinsi Aceh artinya semakin tinggi angka belanja pegawai maka akan menurunkan pertumbuhan ekonomi di Provinsi Aceh.Kebikalan fiskal baik pajak dan belanja pegawai berpengaruh terhadap pertumbuhan ekonomi di provinsi Aceh sebesar 81,8 persen dan sisanya sebesar 18,2 persen dipengaruhi oleh variabel lainnya diluar model penelitian ini.Diharapkan kepada pemerintah daerah dan pemerintah pusat agar dapat membantu dan mendorong kegiatan pertumbuhan ekonomi di provinsi Aceh, dengan tidak sembarangan menaikkan pajak dan belanja pegawai.
ANALISIS HUBUNGAN CADANGAN DEVISA, JUMLAH UANG BEREDAR (JUB) DAN NET EKSPOR TERHADAP NILAI TUKAR RUPIAH DI INDONESIA
Authors: , Murtala
Published: July 2022

Penelitian ini bertujuan untuk menganalisis hubungan cadangan devisa, jumlah uang beredar, dan net ekspor terhadap nilai tukar rupiah di Indonesia. Data yang digunakan dalam penelitian ini adalah data sekunder selama periode Tahun 1988 – 2019. Alat analisis data yang dgunakan ialah metode analisis Vector Auto Regression (VAR). Hubungan cadangan devisa, jumlah uang beredar dan net ekspor tidak sgnifikan terhadap nilai tukar rupiah di Indonesia. Variabel nilai tukar membutuhkan waktu empat sampai delapan tahun untuk kembali pulih akibat shock yang diberikan oleh variabel lain dalam penelitian ini. Kontribusi yang paling dominan terhadap variabel nilai tukar, cadangan devisa dan jumlah uang beredar adalah variabel itu sendiri, sedangkan untuk variabel net ekspor kontribusi terbesar diberikan oleh nilai tukar
MENINGKATKAN PELUANG PEMBERDAYAAN EKONOMI MASYARAKAT MENUJU DIGITALISASI MELALUI PENGUATAN UMKM
Authors: Nita Sri , Iskandar Irham
Published: July 2022

Kajian ini bertujuan menganalisis pengaruh kontribusi usaha mikro, kecil dan menengah terhadap pertumbuhan ekonomi dan strategi kebijakan terhadap pemberdayaan ekonomi masyarakat melalui penguatan UMKM. Populasi dalam penelitian ini adalah keseluruhan penggiat ekonomi UMKM pada sentra-sentra UMKM di Provinsi Aceh. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah purposive sampling. Dalam purposive sampling, pengambilan sampel dilakukan hanya atas dasar pertimbangan penelitinya saja yang menganggap unsur-unsur yang dikehendaki telah ada dalam anggota sampel yang diambil. Sampel penelitian ini adalah 100 penggiat ekonomi UMKM pada sentra-sentra UMKM yaitu Usaha Mikro dan Kecil (UMK), Dinas Koperasi, UKM, Perindustrian dan Perdagangan kabupaten/kota yang tersebar di 5 kabupaten yaitu Kabupaten Pidie, Kabupaten Pidie Jaya, Kabupaten Bireuen, Kabupaten Aceh Selatan dan Kabupaten Aceh Barat Daya.Hasil penelitian menunjukkan indeks pendidikan sebagai variabel moderating memiliki pengaruh terhadap hubungan antara teknologi dan pertumbuhan ekonomi. Hal ini menunjukkan bahwa indeks pendidikan memberikan pemanfaatan teknologi bagi pertumbuhan ekonomi, kemudian strategi kebijakan yang ditempuh adalah meningkatkan strategi pemasaran melalui sosial media dengan mengikuti kemajuan teknologi, meningkatkan kualitas produk dengan melihat daya beli serta permintaan konsumen, lokasi yang sangat strategis untuk memudahkan masyarakat mengaksesnya, memberikan pelayanan kepada konsumen yang maksimal dan meningkatkan variasi produk yang ada dengan melihat selera atau permintaan konsumen di pasaran.
Formulation and Evaluation of Body Lotion Containing Aegle Marmelos Leaf Extract
Authors: S. Gop Rajeshkumar , K. Mudartha Deepti , D. Karmokar Kajol , H. Yadav Anuradha , Maheshwari Veena
Published: July 2022

Skin is the maximally exposed part of the body, that is susceptible to UV radiation, pollution, etc. A body lotion can aid in protection of skin from these detriments with no side effects. Also, there is a growing arena towards natural and herbal cosmetic products for skincare. Keeping all these in mind, this herbal body lotion was prepared from the extract of Aegle marmelos leaves along with other ingredients to form various formulations. Various studies demonstrated medicinal and immunomodulator activities of Aegle marmelos leading to treatment and preventive strategies incombating vivid conditions. Several antioxidant components such as β-carotene, glutathione, α-tocopherol, ascorbic acid, and total polyphenols and flavonoids are rich in Aegle leaves. The objective of our study was to find out the antioxidant potential of Aegle marmelos and thereby using the extract for formulating body lotion for skincare. These formulations were further evaluated for various parameters such as antioxidant assays (DPPH, FRAP, TPC), pH, lotion type, emulsion type, stability, microbial growth, organoleptic properties, spread ability, etc. Body lotion containing methanolic extract of Aegle marmelos showed 50% radical scavenging activity at 172.51 ± 5.60 mg/mL, TPC value of 28.06 ± 0.40 mg/g and FRAP value of 4.08 mM/g. According to the feedback obtained from the volunteers, the colour of lotion was found to be very good, odour and homogeneity of the body lotion was found to be excellent. The spreadability and emolliency was also found to be excellent. The lotion was found to be non-greasy and maximum volunteers did not experience any sort of irritancy. Further studies are needed to test the efficacy of this lotion in various forms like nanoparticles, etc.
Recent Updates On Medicinal Potentiality of Fabaceae Family: Critical Review
Authors: Jadhavar Priyanka , Deshpande Seema
Published: July 2022

Use of Wild plants for medicinal purposes is an ancient tradition that has endured in many rural communities in India. In recent times, the practice of herbal medicine is decreasing. Thus in the rejuvenation of traditional herbal medicines, it is an effort to record the valuable ethno-botanical and ethno-medicinal knowledge. This review covers all aspects of medicinal importance of the Fabaceae family that were missed by some reviewers. Most of the review studies focused on the antibacterial activity of the Fabaceae family but rarely covered all other aspects as well as general health benefits of family Fabaceae in the day to day life. Some important and new aspects such as anticancer, anti-inflammatory, antiviral, antioxidant are also covered in this review article. Several research data have been published in the last decades on this concept but it is noticed that there is no single overview which can cover all medicinal properties of family Fabaceae in a single draft. Under these circumstances present review will serve as a pathfinder to researchers who have keen interest in medicinal properties of Fabaceae. Aim of our study is to focus on all medicinal activities of family Fabaceae and the main objective of this study is to collect new research and review articles using data from Medline, Pubmed, Scopus, Embase etc. The secondary metabolites of this family are very different, including the class of flavonoids, phenolic acids, tannins, anthocyanins, coumarins, saponins, Phyto-steroids and terpenoids. Due to the presence of all these secondary metabolites, it is the second-largest family to be used with therapeutic resources all over the world. Studies reveal important bioactive properties related to different genera and species, such as: analgesic activity, anti-inflammatory, anticancer, antidiabetic, antirheumatic, antimicrobial, antibacterial, cytotoxic, Antioxidant, antiproliferative, anti-leishmania, healing, cardioprotective, myorelaxant, antiulcerogenic, serine protease inhibition, chemoprotective and anti-wrinkles.
An Overview of Quality Audit: A Boon for Pharmaceutical Sector
Authors: Patidar Anita , S. Chhabra Gurmeet , K. Mishra Dinesh
Published: July 2022

This review article covers a combination of aspects of the sole entity which defines the quality of products in the pharmaceutical sector. Quality audit is one of the essential elements of ISO 9001 quality system standards. It assures that an organization has distinctly defined a quality system to manufacture the quality products and work according to it. Concession or negotiation in quality of pharmaceutical products would directly impact the health of patients so audits are performed at specified time interval to ensure the quality as it is benefaction for the companies towards gaining loyalty from customers, maintain regulatory standards, long term revenue and profit. Regulatory bodies have their standard assessment tools termed Audits and Inspection, which reviews and evaluates various records, systems, and procedures followed in an organization. Most of the articles glorify that the quality audits mainly involve documented examinations and verification of all the processes and activities routinely performed, leading to ensure the required quality standards. The article is a result of a collection of data about the principles and objectives of quality audit and the benefits it provides to the respective firm by following the proper audit plan, procedures, corrective actions, and follow up making us aware of methods of gathering information for an audit, a brief knowledge of audit closure meetings, reports and basic criteria for selecting the auditor. Auditors play an important role to guarantee their organization’s consistency with pharmaceutical United States Food and Drug Administration and current Good Manufacturing Practices guidelines and other quality standards like ICH Q10. The article also describes the deficiencies occurring during and after the audit and a case study regarding the audit. The figures represented in the given article comprises the basic principles of audit, types of audits, steps of conducting an audit efficiently, audit management, and flow cycle of audit which gives an overall idea of the running of audit in a consistent manner to check the product meets the regulatory requirements, expected results and patient’s compliance.
Beliren Yetişkinlikte Psikolojik Belirtiler ve Yardım Alma Davranışları
Authors: TUNCA Aslı , BALOĞLU Menekşe
Published: July 2022

Bu çalışmanın amacı, beliren yetişkinlik döneminde olan üniversite öğrencilerinin psikolojik yardım alma davranışlarına göre psikolojik belirtilerini incelemektedir. Araştırma, ilişkisel tarama modelinde betimsel bir çalışmadır. Araştırmanın çalışma evreni üniversitede öğrenim görmekte olan 18-25 yaş aralığındaki gençlerdir. Çalışmada örnekleme yöntemi olarak basit tesadüfi yöntem kullanılmıştır. Veriler, bir kamu üniversitesinin Psikolojik Danışma ve Rehberlik Uygulama ve Araştırma Merkezi aracılığıyla, üniversitede öğrenim görmekte olan öğrencilere çevrimiçi yollarla ulaşılarak elde edilmiştir. Çalışmada “Kişisel Bilgi Formu” ve “Kısa Semptom Envanteri” kullanılmıştır. Toplamda 253 öğrencinin verileri analiz edilmiştir. Bulgulara göre, beliren yetişkinlikte depresyon, hostilitenin ve toplam belirti düzeylerinin yüksek olduğu tespit edilmiştir. Kadınların ve profesyonel psikolojik destek alan bireylerin psikolojik belirtilerinin daha fazla olduğu saptanmıştır. Psikolojik destek alma arayışlarının depresyon için anlamlı farklılık gösterdiği ve psikolojik destek almaya ilişkin gönüllülüğe göre anlamlı farklılık göstermediği tespit edilmiştir. Çalışmada, gençlerde yüksek düzeyde bulunan depresyon ve hostilite bulgularına ve kadın öğrencilerin psikolojik belirtilerinin daha yüksek çıkması bulgusuna dayanarak, üniversitelerde psikolojik danışma ve rehberlik birimlerince bu belirtileri iyileştirmeye yönelik bireysel ve grupla psikolojik danışma faaliyetleri düzenlenebilir, psiko-eğitim çalışmaları yapılabilir. Bu çalışma ile sosyal desteğin önemi anlaşılmıştır. Bu bağlamda aile, arkadaş, partner ilişkilerini geliştirmeye dayalı müdahaleleri ele alan yaklaşımlar beliren yetişkinlere sunulabilir.
Negara, Politik Identitas, dan Makar: Pandangan Organisasi Massa Islam Tentang Makar dan Upaya Pencegahannya Melalui PERPPU Ormas
Authors: Hermawan Sulhani , Sidik Sidik
Published: July 2022

The discourse of mass organization dismissal of Hizbut Tahrir Indonesia (HTI) by the government through the Government Regulation in Lieu of Law No. 2/2017 (Perppu), that now has been officially being the mass organization regulation, causes pro and contra.This article analyses the substance of the differencies of HTI, NU, and Muhammadiyah opinion about violant attack (makar) and Perppu as its rule to protect it. It also analyses the rationale and reason of their opinion. This article finds two points: First, HTI noted that their activities were not a violant attack but the religious proselytizing (dakwah) so that the dimissal act through Perppu, according to them, was not appropriate. Meanwhile, NU said that HTI activities were a violant attack and they supported itsdismissal through Perppu. Whereas Muhammadiyah argued that the contradiction toward national idology is a violant attack but it dimissal has to be constitutional. Second, based on the social dialectic theory, this article notes that the differencies of these mass organization opinion were influenced by their different conception on nation that internalized when they looked at the problem of violant attack and Perppu. According to the political identity theory, each mass organization brings religious knowledge identity that fitted together, especially concerning Perppu.
 
Diskursus terkait penonaktifan organisasi massa (ormas) Hizbut Tahrir Indonesia (HTI) oleh pemerintah melalui Peraturan Pemerintah Pengganti Undang-Undang No. 2 tahun 2017 (Perppu Ormas), yang kemudian disahkan menjadi UU Ormas, memunculkan pro-kontra. Artikel ini mengkaji bagaimana substansi perbedaan pandangan HTI, Nahdhatul Ulama (NU), dan Muhammadiyah (MU) tentang makar dan Perppu sebagai payung hukum pencegahannya. Lantas, apa sebenarnya yang melandasi perbedaan pandangan tersebut. Kajian ini menemukan beberapa hal. Pertama, HTI berpandangan bahwa aktivitas mereka bukan makar melainkan aktivitas dakwah sehingga pembubarannya melalui Perppu dinilai tidak beralasan. Sementara NU memandang aktivitas HTI adalah makar dan mendukung pembubarannya melalui Perppu. Adapun Muhammadiyah berpandangan bahwa yang bertentangan dengan ideologi negara adalah makar, tapi pencegahannya harus secara konstitusional. Kedua, merujuk pada teori dialektika sosial, perbedaan sikap masing-masing ormas dipengaruhi oleh pandangan mereka tentang konsepsi negara yang terinternalisasi dalam menyikapi persoalan makar dan pencegahannya melalui Perppu. Sementara berdasarkan teori politik identitas, masing-masing ormas mengusung identitas pemahaman keagamaan yang saling beririsan terkait Perppu.
Quantitative Structural Edge-version Topological Descriptors for Boric Acid Graphite Structure
Authors: J Sahaya Vijay , Santiago Roy
Published: July 2022

A quantitative structural analysis was carried out to predict the
physical properties of boric acid structure. A topological descriptor of
chemical molecule structure is a numerical value that distinguishes
between a base structure and its branching pattern in the knowledge of
chemical, physical, and biological aspects of molecular structure. In
modern chemistry, theoretical chemistry, pharmacology, toxicology, and
environmental chemistry, a large number of numerical graph invariants
(topological indices) have been established and used for correlation
analysis. In this paper, edge-version of distance based topological
descriptors like edge Wiener, edge Szeged, edge PI and vertex-edge
Wiener are computed for the structure of boric acid graphite sheet and
Theta, Omega, Sd and PI polynomials and their subsequent topological
indices for boric acid graphite structure are quantified. Further, using
Theta and Omega polynomials, we devise a new approach for calculating
the PI and Sd indices.
Incidental finding of Tuberous Sclerosis Complex in a woman with Hematuria: A Case Report of Renal Angiomyolipoma and Review of the Literature
Authors: Adhikari Gauri , Pandey Prabin , Bhattarai Kishor , Khadka Chhabi , Adhikari Gopal
Published: July 2022

Tuberous sclerosis complex (TSC) is a rare genetic multisystem disorder
that was first described by Von Recklinghausen. We report a case of a
female who initially presented with hematuria and was later found to
have multiple manifestations of the disease. The report emphasizes the
value of investigations on suspected cases.
Medicinal properties of vinca alkaloid (Catharanthus roseus) and their impact on human health
Authors: Malhotra Meenakshi , Tandon Pooja , Melkani Indu , Wadhwa Kritika , Singh Ajeet , Singh Amar Pal
Published: July 2022

Abstract: Medicinal plants, contain a variety of phytochemicals
promising as traditional medicine for the treatment of chronic and
infectious diseases, has been safe and effective alternatives with fewer
side effects than synthetic agents. Catharanthus roseus (L.) G. Don (C.
roseus) has been widely available and used to treat various diseases in
many countries. It is attracting more and more attention as it has been
shown to have a wide range of phytochemicals with various biological
activities such as antioxidant, antibacterial, antifungal, antidiabetic
and anticancer characteristic. Notably, vinblastine and vincristin
isolated from this plant were the first plants derived from this plant
anticancer agents deployed for clinical purposes. In addition,
vindoline, vindolidine, vindolicine and vindolinine isolated from C.
roseus leaves showed antidiabetic properties. These findings indicate
that the plant remains a promising source of bioactive substances. This
article provides an overview of the tradition use and pharmacological
uses of C. roseus, and a summary of updated health benefits of extracts
and bioactive compounds derived from this plant have also been addressed
to support their potential as therapeutic agents.
Pseudo compact almost automorphic solutions to a family of non-monotone delayed differential equations
Authors: Zheng Fengxia , Li Hong-Xu
Published: July 2022

In this paper, a family of non-monotone differential equations with
mixed delays is considered. By introducing a concept of Bi-pseudo
compact almost automorphic functions and establishing the properties of
these functions, and using Halanay’s inequality and Banach fixed point
theorem, some results on the existence, uniqueness and global
exponential stability of pseudo compact automorphic solutions of the
equations are obtained. Our results extend some recent works. Moreover,
an example is given to illustrate the validity of our results.
Global well-posedness and energy decay for a one dimensional porous-elastic system subject to a neutral delay
Authors: Labidi Sara , Khochemane, Houssem Eddine , Loucif Sami , Djebabla Abdelhak
Published: July 2022

In this article, we consider a one-dimensional porous-elastic system
with porous-viscosity and a distributed delay of neutral type. First, we
prove the global existence and uniqueness of the solution by using the
Faedo–Galerkin approximations along with some energy estimates. Then,
based on the energy method and by constructing a suitable Lyapunov
functional as well as under an appropriate assumptions on the kernel of
neutral delay term, we show that despite of the destructive nature of
delays in general, the damping mechanism considered provockes an
exponential decay of the solution for the case of equal speed of wave
propagation. In the case of lack of exponential stability, we show that
the solution decays polynomially.
Assessing the importance of seed priming for seed germination in Muscari.
Authors: ROHOLLAHI IMAN , Labbaf Narjes , NAJI Amir Mohammad
Published: July 2022

Muscari with absorbing color is a widespread and commercial species. As
a pot and bedding bulb flower has excellent adaptability and vigorous
growth in late winter and early spring. In our experiment, the quantity
and uniformity of Muscari propagation by seed and the importance of seed
priming will be measured. The selected M. neglectum populations which
already were gathered in our previews research and M. armeniacum were
evaluated under separated sulfuric acid (5, 15, and 20 min) and hot
water (5, 15, and 20 min) scarification plus 15, 30, and 45 days
stratification in a completely randomized design, four replications were
planted in separate containers. Seeds of M. armeniacum only germinate
(70%) by 15 min sulfuric acid plus 45-day stratification treatments.
Based on the analysis of variance and mean comparison data that only
were reported in M. neglectum, their seeds optimally germinated by 5 and
15 min sulfuric acid treatment plus 45-day stratification. In
conclusion, M. neglectum seeds germination is tuned to take place well
in mid-winter under natural conditions; on the other hand, 45 days of
lengthy constant stratification and 5 min sulfuric acid priming will
accelerate M. neglectum seeds germination.
Hybrid immunity and protection against infection during the Omicron wave in Malta
Authors: Cauchi John Paul , Dziugyte Ausra , Borg Maria-Louise , Melillo Tanya , Zahra Graziella , Barbara Christopher , Souness Jorgen , Agius Steve , Calleja Neville , Gauci Charmaine , Vassallo Pauline , Baruch Joaquin
Published: July 2022

Background: By December 2021, administration of the third dose of
COVID-19 vaccinations coincided with the spread of the Omicron variant
in Europe. Questions had been raised on protection against infection
conferred by previous vaccination and/or infection. Method: Our study
population (n = 252,433) included all those in the COVID-19 vaccination
registry in Malta who were vaccinated with only 2 doses equivalent by
15th December 2021, and not vaccinated with an additional dose by 8th
March 2022, and alive by 8th March 2022. Data were then matched with the
national testing database (all RT-PCR/Rapid Diagnostic Tests - RDT
tests) until 8th March. We collected vaccination status, vaccine brand,
vaccination date, infection history, and age. Using logistic regression,
we examined different combinations of vaccine dose, prior infection
status and time, and the odds of infection during the Omicron period
(December 15th, 2021 onwards). Results: Results found that participants
infected with Sars-Cov-2 prior to the Omicron wave had a significantly
lower odds of being infected with the Omicron variant. Additionally, the
more recent the infection and the more recent the vaccination, the lower
the odds of infection. Receiving a third dose within 20 weeks of the
start of the Omicron wave in Malta offered similar odds of infection as
receiving a second dose within the same period. Conclusion: Time since
vaccination is a strong determinant factor against infection, as was
previous infection status and the number of doses taken. This finding
reinforces the importance of future booster dose provision especially to
vulnerable populations.
Information Security Incident Handling in the Cloud
Authors:   Digital Forensics and Cyber Security Graduate Programme Department of Information Systems & Innovations Ghana Institute of Management & Public Administration Greenhill, Accra, Ghana E-mail: abram.sackey@gmail.com, Sackey Abraham
Published: July 2022

Information security incident handling in the cloud is an integral part of security management, threats detection and analysis of security incidents. The strategies or models are important to ensure the security of an organization particularly in cloud and big data environment. Incident handling strategy is one key strategy to mitigate risks to the confidentiality, integrity and availability of organizational assets, as well as minimizing loss. This study concluded that cloud-based services has changed many organizational cyber threats. It recommended that, there is the need to integrate digital forensics with incident handling. This study suggested that, a collaborative model can be implemented, and this collaboration could be centrally managed by a trusted entity (e.g., Centre for Cloud Incident Management). Further studies are required in monitoring incidents both proactive and reactively. Key words: Information Security, Incident Handling, Cloud, Cyber Security, Protection, Data
Contemporary research trends in computer science and informatics - editorial
Authors: Ivanovic Mirjana , Radovanovic Milos , Kurbalija Vladimir
Published: July 2022

nema
Guest editorial - Intelligent systems and their applications
Authors: Kilimci Hilal , Solak Serdar , Eken Süleyman
Published: July 2022

nema
Development aid benefits for donor countries
Authors: Hunjak Stula Vladimir
Published: July 2022

The article is based on the doctoral dissertation: ?International Development
Aid as an Instrument for Achieving the Foreign Policy Objectives of France
and Germany?. The main hypothesis of this article is that development aid is
being used as an instrument for achieving foreign policy objectives and that
it is, in this sense, primarily beneficial for donor countries. The article
analyses the developmental inequality in the modern global capitalist order
and the impact of corporations and development aid on the maintenance of
such a system. The article focuses on two main EU member states: the
Republic of France and the Federal Republic of Germany. By shifting the
paradigm from the one in which less developed countries benefit the most
from development aid policies to the one in which, in the long run, the
countries that initiate these policies benefit the most, the article shows
that larger and politically and economically more powerful countries use
development aid policies to promote their own interests and achieve their
foreign policy goals.