bluuebunny/crossref_metadata_2025 huggingface dataset:
Sex Pheromone of the Alfalfa Plant Bug, Adelphocoris lineolatus: Pheromone Composition and Antagonistic Effect of 1-Hexanol (Hemiptera: Miridae)
Authors: Koczor Sándor , Vuts József , Caulfield John C. , Withall David M. , Sarria André , Pickett John A. , Birkett Michael A. , Csonka Éva Bálintné , Tóth Miklós
Published: April 2021

The sex pheromone composition of alfalfa plant bugs, Adelphocoris lineolatus (Goeze), from Central Europe was investigated to test the hypothesis that insect species across a wide geographical area can vary in pheromone composition. Potential interactions between the pheromone and a known attractant, (E)-cinnamaldehyde, were also assessed. Coupled gas chromatography-electroantennography (GC-EAG) using male antennae and volatile extracts collected from females, previously shown to attract males in field experiments, revealed the presence of three physiologically active compounds. These were identified by coupled GC/mass spectrometry (GC/MS) and peak enhancement as hexyl butyrate, (E)-2-hexenyl butyrate and (E)-4-oxo-2-hexenal. A ternary blend of these compounds in a 5.4:9.0:1.0 ratio attracted male A. lineolatus in field trials in Hungary. Omission of either (E)-2-hexenyl-butyrate or (E)-4-oxo-2-hexenal from the ternary blend or substitution of (E)-4-oxo-2-hexenal by (E)-2-hexenal resulted in loss of activity. These results indicate that this Central European population is similar in pheromone composition to that previously reported for an East Asian population. Interestingly, another EAG-active compound, 1-hexanol, was also present in female extract. When 1-hexanol was tested in combination with the ternary pheromone blend, male catches were reduced. This compound showed a dose-response effect with small doses showing a strong behavioral effect, suggesting that 1-hexanol may act as a sex pheromone antagonist in A. lineolatus. Furthermore, when (E)-cinnamaldehyde was field tested in combination with the sex pheromone, there was no increase in male catch, but the combination attracted both males and females. Prospects for practical application are discussed.
The influence of in-group and out-group favouritism on the disciplinary practice of ethnic majority and minority preservice teachers
Authors: Schuchart Claudia , Glock Sabine , Dunkake Imke
Published: April 2021

Teacher judgments and the disciplinary sanctioning of pupils can be understood as a function of the ethnic match, which means whether or not teachers and pupils have the same ethnic background. According to social identity theory, teachers should be motivated to protect positive self-esteem and therefore favour pupils of their ethnic in-group over pupils of their ethnic out-group. Following system justification theory however, it must be assumed that teachers also base their judgments and their disciplinary behaviour on the acceptance of social hierarchies. According to this theory, ethnic minority teachers should therefore favour ethnic majority pupils over ethnic minority pupils. We test these hypotheses by conducting an experimental study among 196 preservice teachers. The results suggest that ethnic majority participants do not discriminate against ethnic minority pupils. However, although ethnic minority participants seem to explicitly favour their in-group, they also implicitly tend to have more negative stereotypes about them. Moreover, the more negative explicit and implicit stereotypes ethnic minority participants have against pupils of their in-group, the more severely they punish pupils of their out-group. This could suggest that ethnic minority participants felt the desire to compensate for a negative view of their in-group by treating their out-group more harshly.
A new paradox and the reconciliation of Lorentz and Galilean transformations
Authors: Guo Hongyu
Published: April 2021

One of the most debated problems in the foundations of the special relativity theory is the role of conventionality. A common belief is that the Lorentz transformation is correct but the Galilean transformation is wrong (only approximately correct in low speed limit). It is another common belief that the Galilean transformation is incompatible with Maxwell equations. However, the “principle of general covariance” in general relativity makes any spacetime coordinate transformation equally valid. This includes the Galilean transformation as well. This renders a new paradox. This new paradox is resolved with the argument that the Galilean transformation is equivalent to the Lorentz transformation. The resolution of this new paradox also provides the most straightforward resolution of an older paradox which is due to Selleri in (Found Phys Lett 10:73–83, 1997). I also present a consistent electrodynamics formulation including Maxwell equations and electromagnetic wave equations under the Galilean transformation, in the exact form for any high speed, rather than in low speed approximation. Electrodynamics in rotating reference frames is rarely addressed in textbooks. The presented formulation of electrodynamics under the Galilean transformation even works well in rotating frames if we replace the constant velocity $$\mathbf {v}$$
v
with $$\mathbf {v}=\varvec{\omega }\times \mathbf {r}$$

v
=

ω

×
r

. This provides a practical tool for applications of electrodynamics in rotating frames. When electrodynamics is concerned, between two inertial reference frames, both Galilean and Lorentz transformations are equally valid, but the Lorentz transformation is more convenient. In rotating frames, although the Galilean electrodynamics does not seem convenient, it could be the most convenient formulation compared with other transformations, due to the intrinsic complex nature of the problem.
Genotype-dependent mass somatic embryogenesis: a chance to recover extinct populations of Pulsatilla vulgaris Mill.
Authors: Żabicka Justyna , Żabicki Piotr , Słomka Aneta , Jędrzejczyk-Korycińska Monika , Nowak Teresa , Sliwinska Elwira , Kapler Adam , Migdałek Grzegorz , Kuta Elżbieta
Published: April 2021

The paper presents a technique for micropropagation of endangered in Europe and extinct in Poland Pulsatilla vulgaris for ex situ conservation of the genetic resources. Genotype-dependent induction of somatic embryogenesis and rooting was revealed in series of two experiments (I and II) performed under the same experimental conditions. Shoot tips of seedlings were the best explants in both experiments and Murashige and Skoog (MS) medium supplemented with 0.25 or 0.5 mg L−1 BAP was suitable for induction of somatic embryos (SE) and adventitious shoots. Mass SE was obtained in experiment I after explants transfer on ½ MS (2% sucrose) + 0.45 mg L−1 B1 and extending culture to 2–3 months without passages. Rooting of adventitious shoots was a critical point. Out of seven rooting media used in experiment I, only two, ½ MS hormone free (2% sucrose) + 0.45 mg L−1 B1 or MS + 5 mg L−1 NAA + 3.76 mg L−1 B2 resulted in altogether 36.4% rooted shoots. In experiment II, somatic embryogenesis, rooting and acclimatization of adventitious shoots failed. Regenerated plantlets and seedlings converted from SE from experiment I were acclimatized to ex vitro conditions. Both genome size, determined by flow cytometry, and genetic diversity analyzed by ISSR markers, confirmed the compatibility of regenerants from experiment I with P. vulgaris initial seedlings and commercial cultivar. Regenerants obtained in experiment II differed genetically from the regenerants of experiment I and cultivar. Propagated in vitro tissues/organs (SE, adventitious shoots) of P. vulgaris could be a source of material for cryopreservation, artificial seed production and/or for acclimatization of regenerated plantlets and could be used for restoration of the extinct populations.

Key Message

The micropropagation technique via organogenesis and somatic embryogenesis of endangered in Europe pasqueflower was developed as a tool for species recovery. The critical point is that somatic embryogenesis is genotype-dependent, which affects the repeatability of the experiments and also imposes applying molecular techniques to confirm the genetic fidelity of the regenerants with the initial material and other genotypes.
Are acute sitting-induced changes in inflammation and cerebrovascular function related to impaired mood and cognition?
Authors: Carter Sophie E. , Draijer Richard , Stewart Claire E. , Moss Andy D. , Thijssen Dick H. J. , Hopkins Nicola D.
Published: April 2021

Purpose

Sedentary behaviour is negatively associated with mood and cognition, yet how acute sitting contributes to these overall associations is unknown. Since sitting heightens inflammation and impairs cerebrovascular function, this study investigated the hypothesis that these sitting-induced changes are related to impaired mood and cognition.

Methods

Twenty-five healthy desk workers (18 male, 28.3 ± 7.5 years, BMI: 24.2 ± 3.3 kg∙m−2) were recruited. During laboratory visit one, participants were familiarised with cognitive performance tests measuring executive function, attention and working memory. During laboratory visit two, participants completed 6 h of continuous, uninterrupted sitting. At baseline and after 6 h, serum markers of inflammation, middle cerebral artery blood flow velocity (MCAv), cerebrovascular carbon dioxide reactivity (CVR), dynamic cerebral autoregulation (CA), cognitive performance and mood (positive and negative affect, alert, contented and calm) were assessed. Data were analysed using paired-samples t tests and correlation analyses.

Results

Following sitting, C-reactive protein (∆-1.0 µg/ml) and tissue plasminogen activator (∆-360.4 pg/ml) decreased (p < 0.05), MCAv reduced (∆-2.9 cm∙s−1, p = 0.012) and normalised gain increased in the very low frequency range, indicating impaired CA (∆ + 0.22%·mmHg−1, p = 0.016). Positive affect (∆-4.6, p < 0.001), and alert (∆-10.6 p = 0.002) and contented (∆-7.4, p = 0.006) mood states also decreased following sitting. No significant changes in interleukin-6, tumour necrosis factor-alpha, von Willebrand factor, CVR or cognitive performance were observed (p > 0.05). The observed changes in inflammation and cerebrovascular function were not related to changes in mood (p > 0.05).

Conclusion

Alterations in inflammation or cerebrovascular function following six hours of prolonged, uninterrupted sitting are not related to the observed reductions in mood, indicating other mechanisms underlie the relationship between acute sitting and mood disturbances.
Biophysical mechanism of the interaction between default mode network and working memory network
Authors: Yuan Yue , Pan Xiaochuan , Wang Rubin
Published: April 2021

Default mode network (DMN) is a functional brain network with a unique neural activity pattern that shows high activity in resting states but low activity in task states. This unique pattern has been proved to relate with higher cognitions such as learning, memory and decision-making. But neural mechanisms of interactions between the default network and the task-related network are still poorly understood. In this paper, a theoretical model of coupling the DMN and working memory network (WMN) is proposed. The WMN and DMN both consist of excitatory and inhibitory neurons connected by AMPA, NMDA, GABA synapses, and are coupled with each other only by excitatory synapses. This model is implemented to demonstrate dynamical processes in a working memory task containing encoding, maintenance and retrieval phases. Simulated results have shown that: (1) AMPA channels could produce significant synchronous oscillations in population neurons, which is beneficial to change oscillation patterns in the WMN and DMN. (2) Different NMDA conductance between the networks could generate multiple neural activity modes in the whole network, which may be an important mechanism to switch states of the networks between three different phases of working memory. (3) The number of sequentially memorized stimuli was related to the energy consumption determined by the network's internal parameters, and the DMN contributed to a more stable working memory process. (4) Finally, this model demonstrated that, in three phases of working memory, different memory phases corresponded to different functional connections between the DMN and WMN. Coupling strengths that measured these functional connections differed in terms of phase synchronization. Phase synchronization characteristics of the contained energy were consistent with the observations of negative and positive correlations between the WMN and DMN reported in referenced fMRI experiments. The results suggested that the coupled interaction between the WMN and DMN played important roles in working memory.
High-Performance Polyamide/Carbon Fiber Composites for Fused Filament Fabrication: Mechanical and Functional Performances
Authors: Dul Sithiprumnea , Fambri Luca , Pegoretti Alessandro
Published: April 2021

This study is focused on the 3D printing by fused filament fabrication (FFF) process of short carbon-fiber-reinforced polyamide (PA) composites. In particular, the effect of short carbon fiber (CF) on the mechanical, electrical and piezoresistivity properties of 3D-printed polyamide (PA) composite parts has been analyzed. In comparison with neat PA, the results revealed that the carbon fibers effectively improved all assessed mechanical properties of PA/CF composites. In particular, in XY build orientation, PA/CF 3D-printed composites exhibited a tensile strength of 96 MPa and a tensile modulus of 7.9 GPa, with an increment of + 34 and + 147%, respectively, when compared to the neat PA. Interlayer strength of 3D-printed PA and PA/CF composites reaches similar values, in the range 26-28 MPa. The impact strength of 3D-printed XY parts was reduced by the presence of CF. However, the fracture toughness of PA/CF composite 3D-printed parts was slightly higher in comparison with that of neat PA. Electrical resistivity of PA/CF 3D-printed parts is gradually decreasing from 1.7 × 104 to 0.7 × 104 Ω cm in the temperature range from − 16 to 100 °C. The piezoresistivity tests revealed that an exponential resistance change occurs for both compression-molded and 3D-printed PA/CF samples once strained in tension. A gauge factor of 3D-printed parts of about 65 ± 5 was determined from cyclic strains in the elastic region.
Is accurate routine cancer prognostication psychologically harmful? 5-year outcomes of life expectancy prognostication in uveal melanoma survivors
Authors: Brown Stephen L. , Fisher Peter , Hope-Stone Laura , Damato Bertil , Heimann Heinrich , Hussain Rumana , Cherry M. Gemma
Published: April 2021

Purpose

Prognostication in cancer is growing in importance as increasingly accurate tools are developed. Prognostic accuracy intensifies ethical concerns that a poor prognosis could be psychologically harmful to survivors. Uveal melanoma (UM) prognostication allows survivors to be reliably told that life expectancy is either normal (good prognosis) or severely curtailed because of metastatic disease (poor prognosis). Treatment cannot change life expectancy. To identify whether prognosis is associated with psychological harm, we compared harm in UM survivors with good and poor prognoses and those who declined testing and compared these outcomes to general population norms.

Methods

Non-randomized 5-year study of a consecutive series of 708 UM survivors (51.6% male, mean age 69.03, SD=12.12) with observations at 6, 12, 24, 36, 48 and 60 months. We operationalized psychological harm as anxiety and depression symptoms, worry about cancer recurrence (WREC) and poor quality of life (QoL).

Results

Compared to other groups, survivors with poor prognoses showed initially elevated anxiety and depression and consistently elevated worry about local or distant recurrence over 5 years. Good prognoses were not associated with outcomes. Generally, no prognostic groups reported anxiety, depression and WREC or QoL scores that exceeded general population norms.

Conclusions

Using a large sample, we found that harm accruing from a poor prognosis was statistically significant over 5 years, but did not exceed general non-cancer population norms.

Implications for Cancer Survivors

Survivors desire prognostic information. At a population level, we do not believe that our findings show sufficiently strong links between prognostication outcome and psychological harm to deny patients the option of knowing their prognosis. Nonetheless, it is important that patients are informed of potential adverse psychological consequences of a poor prognosis.
Unbounded Wiener–Hopf Operators and Isomorphic Singular Integral Operators
Authors: Castrigiano Domenico P. L.
Published: April 2021

Some basics of a theory of unbounded Wiener–Hopf operators (WH) are developed. The alternative is shown that the domain of a WH is either zero or dense. The symbols for non-trivial WH are determined explicitly by an integrability property. WH are characterized by shift invariance. We study in detail WH with rational symbols showing that they are densely defined, closed and have finite dimensional kernels and deficiency spaces. The latter spaces as well as the domains, ranges, spectral and Fredholm points are explicitly determined. Another topic concerns semibounded WH. There is a canonical representation of a semibounded WH using a product of a closable operator and its adjoint. The Friedrichs extension is obtained replacing the operator by its closure. The polar decomposition gives rise to a Hilbert space isomorphism relating a semibounded WH to a singular integral operator of Hilbert transformation type. This remarkable relationship, which allows to transfer results and methods reciprocally, is new also in the thoroughly studied case of bounded WH.
Kant and Russell on Leibniz’ Existential Assertions
Authors: Rossi Alessandro
Published: April 2021

Leibniz believed in a God that has the power to create beings and whose existence could be a priori demonstrated. Kant (KrV, A 592-602/B 620-630) objected that similar demonstrations all presuppose the false claim that existence is a real property. Russell (London and New York: Routledge, 1992) added that if existence were a real property Leibniz should have concluded that God does not actually have the power to create anything at all. First, I show that Leibniz’ conception of existence is incompatible with the one that Russell presupposes. Subsequently, I argue that on Leibniz’ conception of existence Russell’s objection is immediately undermined.
„So soll es sein“
Authors: Schmidt Holger
Published: April 2021

Aufgabe der Sozialen Arbeit ist auch die Reproduktion sozialer Normen. Dies geschieht in pädagogischen Normverhandlungen und setzt ein spezifisches Arbeitsverhältnis voraus, welches auf einer gegenseitigen Anerkennung beruht. Als fachliche Orientierung wird die negative Freiheit als normativer Horizont vorgeschlagen.
“The Earth Calculus”: Babbage, tables, and the calculating machine in the study of geology
Authors: Petrocelli Carla
Published: April 2021

Charles Babbage is best known as a pioneer of computer science, but his contributions to the study of the Earth are not as well known. A curious and tireless traveler, on one of his trips to Italy, he dwelt on the remains of the Temple of Serapis, located about one-hundred feet from the coast of the small bay near Pozzuoli, south-west of Naples. On his return to England, also using his Difference Engine, he developed a theory to explain the phenomena related to the area of Serapeo, accompanied by illustrations and mathematical calculations, aimed at explaining the geological phenomena that had helped to make the site so interesting. With the same precision used for his calculation engine, Babbage proposed innovative techniques for the printing of diagrams and tables to be used in earth sciences. Just as his calculation engine had to be reliable by helping to eliminate human error, so the innovative techniques proposed had to allow a representation of geology as a reliable scientific experience.
Robust Landing Control of a Quadcopter on a Slanted Surface
Authors: Choi Jiwook , Cheon Donghun , Lee Jangmyung
Published: April 2021

A robust landing control algorithm is proposed for a quadcopter, as well as for a landing platform to land on an inclined or problematic surface. To use the quadcopter for outdoor application, it is necessary to design a landing platform that can withstand environmental obstacles such as wind and weight load during landing. Conventional retractor landing platforms are not suitable for achieving a stable landing on inclined surfaces or obstacles. Therefore, in this paper, 2-link structured landing legs are applied to stably land on an inclined surface or obstacle with a suitable control algorithm. To achieve stable landing on a slanted surface, a cooperative control algorithm of the quadcopter and the landing platform has been proposed. The proposed robust landing system comprises two controllers, i.e., a high-speed proportional derivative control for the landing platform and a neural network-based proportional–integral–derivative control for controlling the quadcopter in real time. A quadcopter with a robust landing platform has been implemented, and the performance of the robust landing control algorithm has been demonstrated with the system.
An Interdisciplinary Perspective on the Value of Envy
Authors: Lange Jens , Protasi Sara
Published: April 2021

The public and scholars alike largely consider envy to be reprehensible. This judgment of the value of envy commonly results either from a limited understanding of the nature of envy or from a limited understanding of how to determine the value of phenomena. Overcoming this state requires an interdisciplinary collaboration of psychologists and philosophers. That is, broad empirical evidence regarding the nature of envy generated in psychological studies must inform judgments about the value of envy according to sophisticated philosophical standards. We conducted such a collaboration. Empirical research indicates that envy is constituted by multiple components which in turn predict diverse outcomes that may be functional for the self and society. Accordingly, the value of envy is similarly nuanced. Sometimes, envy may have instrumental value in promoting prudentially and morally good outcomes. Sometimes, envy may be non-instrumentally prudentially and morally good. Sometimes, envy may be bad. This nuanced perspective on the value of envy has implications for recommendations on how to deal with envy and paves the way toward future empirical and theoretical investigations on the nature and the value of envy.
Pharmaceutical design of a delivery system for the bacteriocin lacticin 3147
Authors: Ryan Aoibhín , Patel Pratikkumar , O’Connor Paula M. , Ross R. Paul , Hill Colin , Hudson Sarah P.
Published: April 2021

Lacticin 3147 is a dual-acting two-peptide bacteriocin which is generally active against Gram-positive bacteria, including Listeria monocytogenes and antimicrobial-resistant bacteria such as Closteroides difficile in the colon. L. monocytogenes infections can cause life-long effects in the elderly and vulnerable and can cause severe complications in pregnant women. C. difficile causes one of the most common healthcare-associated infections and can be fatal in vulnerable groups such as the elderly. Although lacticin 3147 is degraded by intestinal proteases and has poor aqueous solubility, encapsulation of the bacteriocin could enable its use as an antimicrobial for treating these bacterial infections locally in the gastrointestinal tract. Lacticin 3147 displayed activity in aqueous solutions at a range of pH values and in gastric and intestinal fluids. Exposure to trypsin and α-chymotrypsin resulted in complete inactivation, implying that lacticin 3147 should be protected from these enzymes to achieve successful local delivery to the gastrointestinal tract. The amount of lacticin 3147 dissolved, i.e. its solution concentration, in water or buffered solutions at pH 1.6 and 7.4 was low and varied with time but increased and was stabilized in gastrointestinal fluids by the phospholipid and bile salt components present. Thus, the feasibility of a solid lipid nanoparticle (SLN) delivery system for local administration of lacticin 3147 was investigated. Bacteriocin activity was observed after encapsulation and release from a lipid matrix. Moreover, activity was seen after exposure to degrading enzymes. Further optimization of SLN delivery systems could enable the successful pharmaceutical development of active lacticin 3147 as an alternative to traditional antibiotics.

Graphical abstract
Who Is Not Linking to HIV Care in Tennessee — the Benefits of an Intersectional Approach
Authors: Pierce Leslie J. , Rebeiro Peter , Brantley Meredith , Fields Errol L. , Jenkins Cathy A. , Griffith Derek M. , Conserve Donaldson , Shepherd Bryan , Wester Carolyn , Ahonkhai Aima A.
Published: April 2021

Introduction

Guided by an intersectional approach, we assessed the association between social categories (individual and combined) on time to linkage to HIV care in Tennessee.

Methods

Tennessee residents diagnosed with HIV from 2012-2016 were included in the analysis (n=3750). Linkage was defined by the first CD4 or HIV RNA test date after HIV diagnosis. We used Cox proportional hazards models to assess the association of time to linkage with individual-level variables. We modeled interactions between race, age, gender, and HIV acquisition risk factor (RF), to understand how these variables jointly influence linkage to care.

Results

Age, race, and gender/RF weAima A. Ahonkhaire strong individual (p < 0.001 for each) and joint predictors of time to linkage to HIV care (p < 0.001 for interaction). Older individuals were more likely to link to care (aHR comparing 40 vs. 30 years, 1.20, 95%CI 1.11-1.29). Blacks were less likely to link to care than Whites (aHR= 0.73, 95% CI: 0.67-0.79). Men who have sex with men (MSM) (aHR = 1.18, 95%CI: 1.03-1.34) and heterosexually active females (females) (aHR = 1.32, 95%CI: 1.14-1.53) were more likely to link to care than heterosexually active males. The three-way interaction between age, race, and gender/RF showed that Black males overall and young, heterosexually active Black males in particular were least likely to establish care.

Conclusions

Racial disparities persist in establishing HIV care in Tennessee, but data highlighting the combined influence of age, race, gender, and sexual orientation suggest that heterosexually active Black males should be an important focus of targeted interventions for linkage to HIV care.
Constraint multi-objective optimal design of hybrid renewable energy system considering load characteristics
Authors: Chen Yingfeng , Wang Rui , Ming Mengjun , Cheng Shi , Bao Yiping , Zhang Wensheng , Zhang Chi
Published: April 2021

Finding the optimal size of a hybrid renewable energy system is certainly important. The problem is often modelled as an multi-objective optimization problem (MOP) in which objectives such as annualized system cost, loss of power supply probability etc. are minimized. However, the MOP model rarely takes the load characteristics into account. We argue that ignoring load characteristics may be inappropriate when designing HRES for a place with intermittent high load demand. For example, in a training base the load demand is high when there are training tasks while the demand decreases to a low level when there is no training task. This results in an interesting issue, that is, when the loss of power supply probability is determined at a specific value, say 15%, then it is very likely that most of loss of power supply would occur right in the training period which is unexpected. Therefore, this study proposes a constraint multi-objective model to deal with this issue—in addition to the general multi-objective optimization model, the loss of power supply probability over a critical period is set as a constraint. Correspondingly, the non-dominated sorting genetic algorithm II with a relaxed $$\epsilon $$
ϵ
constraint handling strategy is proposed to address the constraint MOP. Experimental results on a real world application demonstrate that the proposed model and algorithm are both effective and efficient.
Community Interest and the International Public Legal Order
Authors: Thin Sarah
Published: April 2021

Traditional ideas about the private nature of the international legal order are increasingly being forced to contend with the development of public legal elements at the international level. The notion of the international community interest is key to understanding these developments and, as such, has transformed our understanding of international law. There are many different approaches to the public/private distinction in law, broadly categorised into relational, public authority, and interest-based approaches. These can be reduced to four key elements of publicness: the existence of a community or public; the universality of the public regime in question with its own boundaries; normative and institutional hierarchies; the objectivity of obligation and responsibility. The development of the community interest and related norms of international law can be seen to have introduced and strengthened all of these elements of publicness within the international legal system. It is thus on its way to becoming an international public legal order. This has important implications for our understanding of international law and the future development of the international legal order.
Corrosion Resistance of Selected Cast Iron Grades Under Deposit Mining Conditions
Authors: Stawarz Marcin , Dojka Malwina
Published: April 2021

The paper analyzes two types of alloyed cast iron used for pump impellers operated in mine working conditions. The research on corrosion resistance of two cast iron grades resistant to abrasive wear was presented. Tests were performed for chromium cast iron (HCCI) grade EN-GJN HV600 (XCr18) (acc. to EN 12513) and high-silicon cast iron HSCI Grade 1 (acc. to ASTM A 518/ A 518M - 99). Deposit mining is characterized by variable working conditions. Both types of cast iron are resistant to abrasive wear and are suitable for loaded elements (e.g. pump impellers). The paper presents a metallographic analysis of selected cast iron grades based on light microscopy. The chemical composition of the tested cast irons was determined with the Leco GDS 500 spectrometer; C and S content was determined with the CS125 Leco Carbon–Sulfur Determinator. The Si content for HSCI Grade 1 was determined by gravimetric method. Corrosion tests were performed under laboratory conditions. In-service tests of cast impellers were performed under real conditions (working mines applications). Corrosion resistance tests were measured with VoltaLab® Potentiostat (PGP 201). Performed tests resulted in the determination of the usefulness of materials used for dewatering pump impellers in mine working conditions. The results of laboratory tests were verified under the operating conditions of cast impellers. In the conditions of transporting a liquid-solid mixture at the moment of appearance of impurities (e.g. chlorine impurities) in the liquid, the impellers from cast iron HCCI revealed a tendency to pitting corrosion, which explains the exploitation results collected in the mining. After laboratory tests for sample from HCCI, the low value of breakdown potential Eb and repassivation Ecp was concluded which says about the absence of pitting corrosion resistance.
Evaluation of Data Errors and Monitoring Activities in a Trial in Japan Using a Risk-Based Approach Including Central Monitoring and Site Risk Assessment
Authors: Kondo Hidenobu , Kamiyoshihara Tomoaki , Fujisawa Kenji , Nojima Toshiaki , Tanigawa Ryohei , Fujiwara Hisataka , Suganami Hideki , Hayashi Yukikazu , Yamaguchi Takuhiro
Published: April 2021

Background

Risk-based monitoring (RBM) is a slow uptake in some trial sponsors. There are three main reasons for this. First, there is the fear of making large investments into advanced RBM technology solutions. Second, it is considered that RBM is most suitable for large, complex trials. Third, there is the fear of errors in both critical and non-critical data, appearing as reduced on-site monitoring is being conducted.

Methods

Our RBM team identified, evaluated, and mitigated trial risks, as well as devised a monitoring strategy. The clinical research associate (CRA) assessed the site risks, and the RBM team conducted central monitoring. We compared all data errors and on-site monitoring time between the partial switching sites [sites that had switched to partial source data verification (SDV) and source data review (SDR)] and the 100% SDV and SDR sites (sites that had implemented 100% SDV and SDR).

Results

Partial switching sites did not require any critical data correction and had a smaller number of data corrections through on-site monitoring than the 100% SDV and SDR sites. The RBM strategy reduced the on-site monitoring time by 30%.

Conclusions

The results suggest that RBM can be successfully implemented through the use of site risk assessment and central monitoring with practically no additional investment in technology and still produced similar results in terms of subject safety and data quality, as well as the cost savings that have been reported in global complex studies.
Correction to: Relationship Between Magnetic Resonance T2-Mapping and Matrix Metalloproteinase 1,3 in Knee Osteoarthritis
Authors: Shi Lei , Wang Kexin , Yu Jinghong , Li Mingkai , Men Guangmei , Ma Gang , Wang Xing
Published: April 2021

The original version of this article unfortunately contained some mistakes.
Georgia v. Russia (II)
Authors: Dzehtsiarou Kanstantsin
Published: April 2021

On January 21, 2021, the European Court of Human Rights (ECtHR or Court) issued its judgment in the interstate case of Georgia v. Russia (II). Georgia complained that Russia committed systemic human rights violations in the course of the 2008 war in South Ossetia and Abkhazia. Both of these regions are de jure parts of Georgia, but they have not been effectively governed by central Georgian authorities since the collapse of the Soviet Union in 1991. During the night of August 7–8, 2008, Georgian artillery attacked Tskhinvali (the administrative capital of South Ossetia). Russian forces entered South Ossetia and Abkhazia the next day. Russian and Georgian troops engaged in hostilities for five days, before agreeing a ceasefire on August 12, 2008. Since then, a significant military contingent of Russian troops has remained in South Ossetia and Abkhazia. The Georgian authorities complained of systemic violations of European Convention on Human Rights (ECHR) Articles 2 (right to life), 3 (prohibition of torture), 5 (right to liberty), and 8 (right to privacy), ECHR Protocol 1 Articles 1 (right to private property) and 2 (right to education), and ECHR Protocol 4 Article 2 (Freedom of movement).
Deploying Health Care Providers During the COVID-19 Pandemic
Authors: Shander Aryeh , Mesrobian Jay , Weiss Jeffrey , Javidroozi Mazyar
Published: April 2021

As the COVID-19 pandemic runs its course around the globe, a mismatch of resources and needs arises: In some areas, health care systems are faced with an increased number of COVID-19 patients potentially exceeding their capacity, whereas, in other areas, health care systems are faced with procedural cancelations and a drop in demands. TeamHealth in Knoxville, Tennessee, a multidisciplinary health care organization, was able to roll out a systemic approach to redeploy its clinicians practicing in the fields of emergency medicine, hospital medicine, and anesthesiology from areas of less need (faced with reduced or no work) to areas outside of their normal practice facing immediate need.
Clinical Characteristics of the First 100 Patients of COVID-19 in Tobruk, Libya: A Brief Report From Low-Resource Settings
Authors: Ismail Faisal , Farag Atiya , Haq Soghra , Kamal Mohammad A.
Published: April 2021

Objective:

This study aims to report the clinical features of a cohort of patients with suspected coronavirus disease (COVID-19) from Tobruk, Libya, and reflect upon the diagnosis challenge in low-resource settings.

Methods:

A descriptive report of the first 100 patients with suspected COVID-19 who have visited the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and COVID-19 screening clinic at the National Centre for Disease Control in Tobruk, Libya.

Results:

The most common presenting symptoms were fever (90%), cough (89%), dyspnea (85%), sore throat (79%), fatigue (78%), headache (64%), loss of smell (52%), loss of taste (53%), loss of appetite (43%), nausea and vomiting (26%), diarrhea (22%), and rhinorrhea (16%); 51% of the patients had lymphocytopenia, whereas 13% had thrombocytopenia. Bilateral infiltrates were the most common radiologic finding on chest X-ray (76%), and COVID-19 IgM and/or IgG antibodies were detected in 80% of the patients, whereas only 37% of the patients were tested positive by the reverse transcriptase polymerase chain reaction (RT-PCR).

Conclusions:

The disease continued its spread across the region. Fever, cough, and dyspnea were the main symptoms; 21% of the patients did not have any chest X-ray abnormalities. Initial negative results for either antibody testing or RT-PCR-testing for COVID-19 do not rule out the infection.
Butler and Postanalytic Philosophy
Authors: Giladi Paul
Published: April 2021

This article has two aims: (i) to bring Judith Butler and Wilfrid Sellars into conversation; and (ii) to argue that Butler's poststructuralist critique of feminist identity politics has metaphilosophical potential, given herpragmaticparallel with Sellars's critique of conceptual analyses of knowledge. With regard to (i), I argue that Butler's objections to the definitional practice constitutive of certain ways of construing feminism is comparable to Sellars's critique of the analytical project geared toward providing definitions of knowledge. Specifically, I propose that moving away from a definition ofwomanto what one may call poststructuralistsites of womanparallels moving away from adefinition of knowledgeto a pragmatic account ofknowledgeas arecognizable standing in the normative space of reasons. With regard to (ii), I argue that the important parallels between Butler's poststructuralist feminism and Sellars's antirepresentationalist normative pragmatism about knowledge enable one to think of her poststructuralist feminism as mapping outpragmaticcognitive strategies and visions fordoing philosophy. This article starts a conversation between two philosophers whom the literature has yet to fully introduce to each other.
The Relationship between Perceived Security Threats and Negative Descriptions of Armenians in Turkish Politics (1946–1960)
Authors: Nefes Türkay Salim
Published: April 2021

How do perceived threats influence politicians’ attitudes towards religious minorities? Examining the Turkish parliamentary records between 1946 and 1960, this study suggests that perceived security threats significantly contribute to Turkish political parties’ negative descriptions of Armenians. The research analyzes speeches about Armenians via a mixed-method content analysis. The findings demonstrate that (a) debate about security threats is a reliable predictor of the political parties’ negative portrayals, and (b) members of the parliament justify their negative views by labeling Armenians as an enemy. The article concludes that perceived threats evoke negative speeches about Armenians in Turkish politics.
Provider perspectives on Asram in Ghana
Authors: Rent Sharla , Bakari Ashura , Plange-Rhule Gyikua , Bockarie Yemah , Kukora Stephanie , Moyer Cheryl A.
Published: April 2021

Neonatal mortality is one of the leading causes of under-five mortality globally, with the majority of these deaths occurring in low- and middle-income countries. In Ghana, there is a belief in an array of newborn conditions, called Asram, that are thought to have a spiritual, rather than physical, cause. These conditions are predominantly managed by traditional healers as they are considered unable to be treated by allopathic medical providers. Through a series of semi-structured qualitative interviews of medical providers in Kumasi, Ghana, conducted in July–August 2018, this study sought to elucidate perspectives of allopathic medical providers about Asram, including the perceived implications of traditional newborn care patterns on newborn health and higher-level neonatal care. Twenty health care providers participated and represented a tertiary care hospital and a district hospital. Medical providers were universally aware of Asram but varied on the latitude they gave this belief system within the arena of newborn care. Some providers rationalized the existence of Asram in the backdrop of high neonatal mortality rates and long-standing belief systems. Others highlighted their frustration with Asram, citing delays in care and complications due to traditional medical treatments. Providers utilized varying approaches to bridge culture gaps with families in their care and emphasized the importance of open communication with the shared goal of improved newborn health and survival. This study describes the importance of providers being aware of socio-cultural constructs within which pregnant women operate and suggests a focus on the shared goal of timely and effective newborn care in Ghana.
Toward a Theory of Offense: Should You Feel Offended?
Authors: Liu Chang
Published: April 2021

The feeling of being offended, as a moral emotion, plays a key role in issues such as slurs, the offense principle, ethics of humor, etc. However, no adequate theory of offense has been developed in the literature, and it remains unclear what questions such a theory should answer. This paper attempts to fill the gap by performing two tasks. The first task is to clarify and summarize the questions of offense into two kinds, the descriptive questions (e.g., what features differentiate offense from similar moral states like anger?) and the normative questions (e.g., what are the conditions for taking offense to be apt?). The second task is to answer these questions by developing what I call ‘the violated norm theory of offense’. According to this theory, feeling offended entails that the norm one endorses is judged to be violated by the offender. Appealing to the violated norm enables this theory to answer the descriptive questions (e.g., taking offense differs from anger because of features like not requiring victims and the difficulty of animal offense) and the normative questions of offense (e.g., taking offense is apt only if the violated norm is universalizable).
Design and control of a cable-driven rehabilitation robot for upper and lower limbs
Authors: Oyman Efe Levent , Korkut Muhammed Yusuf , Yilmaz Cüneyt , Bayraktaroglu Zeki Y. , Arslan M. Selcuk
Published: April 2021

The design and control of a cable-driven rehabilitation robot, which can be configured easily for exercising different articulations such as elbows, shoulders, hips, knees and ankles without requiring any orthosis, are introduced. The passive, active-assisted and active-resisted exercises were designed and implemented using impedance control. The controller could switch between exercises according to the force feedback. The effectiveness of the proposed controller was demonstrated by experimental studies. The robot was tested first with a dummy extremity and then with a healthy subject mimicking various types of patients during the tests. Experimental results showed that satisfactory closed-loop performances were achieved.
Strong Language: Mathew Carey, Sensibility, and the American State, 1819–1835
Authors: VANDECREEK DREW E.
Published: April 2021

Mathew Carey promoted the high tariff as a political expression of humane sentiments that relieved American workers of the misery caused by low wages and unemployment. This made him an early example of a state-builder working outside the state itself, building ideological frames and using emotional appeals to promote the expansion of state capacity. Although other aspects of his protectionism appealed to the republican tradition, Carey meshed his sentimental appeal with the liberalism. Later reformers integrated sensibility with liberalism by reference to the rights of vulnerable parties, but Carey added an appeal to an enlightened self-interest that allowed American manufacturers to profit while protecting workers. Although he became a well-known advocate for the organized provision of social welfare, his continued opposition to the widespread distribution of outdoor relief also suggests that he viewed the policy as a circumscribed federal social-welfare measure providing work rather than direct aid.
COVID-19 re-infection in Shahroud, Iran: a follow-up study
Authors: Zare Fariba , Teimouri Maryam , Khosravi Ahmad , Rohani-Rasaf Marzieh , Chaman Reza , Hosseinzadeh Ali , Jamali Atergeleh Hozhabr , Binesh Ehsan , Emamian Mohammad Hassan
Published: April 2021

Although many people became infected and recovered during the COVID-19 epidemic, the immunity duration and re-infection in recovered patients have recently attracted many researchers. The aim of this study was to evaluate the recurrence of the infection in recovered individuals over a 9-month period after the onset of the COVID-19 epidemic. In this study, data related to COVID-19 patients in Shahroud city were collected using the electronic system for registering suspicious patients and also by checking patients' hospital records. In this study, from 20 March 2020 to 20 November 2020 (9 months), a total of 8734 suspected patients with respiratory symptoms were observed and followed up. RT-PCR was positive for 4039 patients. During this period, out of the total number of positive cases of COVID-19, 10 cases became re-infected after complete recovery. The risk of re-infection was 2.5 per thousand (0.95 CI 1.2–4.5). The mean time interval between the first infection and re-infection was 134.4 ± 64.5 days (range 41–234 days). The risk of re-infection between male and females was not statistically different (1.98 per 1000 women and 2.96 per 1000 men). Exposure to COVID-19 may not establish long-term protective immunity to all patients and may predispose them to re-infection. This fact can be reminded that the use of masks, social distancing and other preventive measures are very important in recovered patients and should be emphasised especially in health care personnel who are more exposed to the virus.
Checklist of the species of notothenioid fishes
Authors: Eastman Joseph T. , Eakin Richard R.
Published: April 2021

We provide our perspective on the species-level taxonomy of notothenioid fishes, the dominant component of the fish fauna of Antarctica. There are 140 species in 45 genera, an increase of 15% since the previous summary in 2000. Biogeographically, 30 species are non-Antarctic, 33 are sub-Antarctic and 77 are Antarctic. The checklist is documented with footnotes that provide the rationale for our decisions. Supplementary Material provides additional details for our decisions on two species ofPogonophryne.
THE NONARITHMETICITY OF THE PREDICATE LOGIC OF STRICTLY PRIMITIVE RECURSIVE REALIZABILITY
Authors: PLISKO VALERY
Published: April 2021

A notion of strictly primitive recursive realizability is introduced by Damnjanovic in 1994. It is a kind of constructive semantics of the arithmetical sentences using primitive recursive functions. It is of interest to study the corresponding predicate logic. It was argued by Park in 2003 that the predicate logic of strictly primitive recursive realizability is not arithmetical. Park’s argument is essentially based on a claim of Damnjanovic that intuitionistic logic is sound with respect to strictly primitive recursive realizability, but that claim was disproved by the author of this article in 2006. The aim of this paper is to present a correct proof of the result of Park.