bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of Maternal and Fetal Factors in Fetal Lesions: Insights from Fetal Autopsies
Authors: Gupta Dr Chandra Prakash , Jadhav Dr Rahul M. , Dahe Dr Swati , Gaikwad Dr Amol R. , Karle Dr Ravindra , Dongre Dr Suryakant
Published: February 2025

Fetal death/Intra uterine death (IUD) is a significant adverse pregnancy outcome, particularly prevalent in low- and middle-income countries. It is also a good indicator of quality of healthcare available. Fetal autopsy is often required to determine the cause of intrauterine death or miscarriages, provide recurrence risk, and is known to alter the ﬁnal diagnosis and genetic counseling. Aim: To study the maternal and fetal factors in fetal autopsy lesions. To know the prevalence of various fetal abnormalities in IUD. Material and methods: The present study was a retrospective observational study conducted in the Department of Pathology at Dr. BVP Rural Medical College, Loni, over a duration of 5 years. A total of 78 cases were included, with data collected on the mother's age, gestational age, fetal gender, weight, and other relevant details, alongside records of fetal autopsies. Special attention was given to identifying organ abnormalities in the fetuses. The collected data was compiled in Microsoft Excel, and the analysis was carried out using Openepi version 3.2.1 software. Results: The study found that mean maternal age was 24.8+ 4.5 years, ranging between 18 to 38 years. Mean gestational age was 21.7 +4 weeks. It was seen that among total 78 cases, 40 were males, 30 were females, 6 fetuses were macerated and 2 fetus gender was ambiguous. Conclusion: The study shows a varied distribution of fetal characteristics, with male fetuses being more common and cardiac abnormalities being the most prevalent. These findings emphasize the diverse nature of fetal lesions and their potential effects on fetal development, influenced by gestational age and maternal conditions.
EFFICIENCY OF MILK CONSUMPTION BY LAMBS
Authors:   Federal State Budgetary Educational Institution of Higher Education "Gorsky State Agrarian University", GOGAEV O.K. , DEMUROVA A.R. ,   Federal State Budgetary Educational Institution of Higher Education "Gorsky State Agrarian University"
Published: February 2025

During the initial period of life, especially in the first few months, the growth of young animals is strongly influenced by the level of milk feeding, as their entire nutritional requirements are covered by milk. The results showed that the lambs ate an average of 77.89 kg of milk before milking, with the highest amount of milk eaten in the first month of life. In each subsequent month of the experimental period, weight gain increased, while milk consumption per 1 kg of body weight gain decreased. In the first month of life, the average daily weight gain of the young rams was 0.151 kg and the milk consumption per 1 kg gain was 6.09 kg. In the second and third months, these values were 0.163-4.86 and 0.205-4.56 kg respectively. In the first month of life, the young ewes gained an average of 0.138 kg per day and consumed 6.54 kg of milk per 1 kg of body weight gain. In the second month, the average daily gain was 0.158 kg and milk consumption was 4.87 kg; in the third month, the values were 0.199 and 4.48 kg. On average, the lambs consumed 6.31 kg of milk per 1 kg of gain in the first month of life. It was found that growing lambs from three months of age to weaning by the suckling-milking method increased milk yield per sheep by 28.0 kg and did not have a negative effect on body weight and wool productivity of the lambs compared to growing with mothers. Feeding oil cake at the rate of 150 g per day per animal during the period from three to five months with simultaneous milking their mothers increased the body weight of lambs at weaning by 10.7-11.7 % and wooliness - by 26.5-24.1 % compared to other groups.
Terapia Gênica no Tratamento da Doença de Alzheimer: Avanços e Perspectivas
Authors: Janyara Anny Azevedo de Andrade  , Gabriel Abdon Batista Pinto Fernandes  , Julia Karla Nascimento Rocha  , Gabriel Oliveira Miranda  , Jordana Teixeira da Nobrega  , Alice Madilza Palmeira Gomes de Arauji  , Thiago Vinicius Santana Costa  , Monyke Oliveira de Souza  , Samantha Chaves Santos  , Juliana D’Angelo Firmino  , Tarcila Fontes Lucena  , Beatriz Beniz Alves Caldeira
Published: February 2025

A doença de Alzheimer (DA) é uma enfermidade neurodegenerativa progressiva que representa a principal causa de demência no mundo. Apesar dos avanços no conhecimento da fisiopatologia da DA, os tratamentos disponíveis ainda são limitados e majoritariamente paliativos. Diante desse cenário, a terapia gênica emerge como uma alternativa promissora, possibilitando a modulação de genes envolvidos na patogênese da doença. Este estudo realizou uma revisão narrativa da literatura para avaliar os avanços e perspectivas da terapia gênica no tratamento da DA. Foram analisados ensaios clínicos e estudos pré-clínicos que abordam o impacto da modulação genética no metabolismo da proteína beta-amiloide, na agregação da proteína tau e na neuroinflamação. Os resultados indicam que a terapia gênica pode contribuir para a melhora cognitiva e a neuroproteção, especialmente por meio do uso de vetores virais, como os vírus adeno-associados (AAV) e lentivirais, que permitem a entrega eficiente de material genético no sistema nervoso central. No entanto, desafios persistem, como a especificidade da terapia, a heterogeneidade da resposta dos pacientes e as limitações dos modelos experimentais. Conclui-se que, apesar das evidências promissoras, são necessários estudos mais robustos para garantir a viabilidade e segurança da aplicação clínica da terapia gênica na DA.
Os impactos da atividade física em idosos: benefícios na qualidade de vida dos indivíduos com doenças cardiovasculares
Authors: Stopassola Camile da Rosa , De Faria Viviane Maria das Graças , Da Silva Maíra Mendes , Macedo Felipe Elias , Cassemiro Jennifer Nayelli Moreira , Rabite Marcelle Silveira , Silva Ana Alice Goulart
Published: February 2025

Introdução: A prática regular de exercícios físicos traz inúmeros benefícios à saúde cardiovascular, especialmente para idosos, como prevenir hipertensão arterial, aterosclerose e acidentes vasculares. Com o aumento da expectativa de vida, as doenças cardiovasculares se tornaram uma preocupação crescente na saúde pública, sendo a principal causa de morbidade e mortalidade em idosos. Portanto, a implementação de programas de prevenção e a promoção de atividades físicas são essenciais para melhorar a saúde e a qualidade de vida dos idosos. Objetivo: Informar a respeito dos benefícios da atividade física para a melhora de doenças do aparelho cardiovascular. Metodologia: Revisão de literatura a partir das bases de dados SciELO e PubMed, de agosto a novembro de 2024. Foram incluídos artigos de 2007 a 2024, sendo das 35 referências, 11 artigos anteriores ao período de 2018, empregando palavras-chave específicas como: atividade física, idosos, problemas cardiovasculares e qualidade de vida. Resultados e discussão: Idosos que praticam exercícios aeróbicos e de força apresentam menor incidência de doenças cardiovasculares, além de melhorar a saúde mental. No entanto, barreiras como medo de quedas e condições de saúde dificultam a adesão à prática regular. Conclusão: Pode-se concluir que idosos fisicamente ativos apresentam menos sintomas associados às doenças cardiovasculares, além de possuírem melhoras significativas na qualidade de vida. Portanto, é de suma importância a criação de intervenções públicas para que essa parcela da população pratique exercícios físicos constantemente.
Avanços no Diagnóstico e Tratamento do Acidente Vascular Cerebral Isquêmico: Terapias Inovadoras e Abordagens de Reabilitação
Authors: Soares Alcantara da Silva Rubia , Costalonga Gomes Ana Luísa , Garcia Lucena Carla Sabrina , Maquileles Firmino David , Do Rosário Costa Igor , Rocha Bizerra Carlos Eduardo , Quinco de Lima Filho Raimundo , Peres da Silva Sarmento Karolina , Lopes Cajubá de Britto Roberto Augusto , Ávila Matheus Henrique , Fernandes Natan Francisco Silva
Published: February 2025

Este artigo visa discutir os avanços no diagnóstico e tratamento do Acidente Vascular Cerebral Isquêmico, utilizando a base de dados PubMed com os termos "Acidente Vascular Cerebral Isquêmico”, “Reabilitação”, “Terapias Inovadoras". Com base nos avanços descritos ao longo da revisão, é possível concluir que o diagnóstico e o tratamento do Acidente Vascular Cerebral Isquêmico (AVCi) evoluíram consideravelmente nos últimos anos, com inovações significativas tanto em terapias farmacológicas quanto em técnicas intervencionistas. A trombectomia mecânica e a trombólise intravenosa ampliaram as opções terapêuticas, melhorando as perspectivas de recuperação funcional para os pacientes. Além disso, a aplicação de terapias neuroprotetoras, aliada ao uso de tecnologias avançadas de imagem, tem mostrado um potencial promissor para reduzir os danos cerebrais e promover a neuroplasticidade. Essas abordagens têm se mostrado eficazes, principalmente quando associadas a um diagnóstico precoce e a uma intervenção rápida. No entanto, apesar dos progressos, ainda existem desafios no manejo do AVCi, principalmente no que se refere à variabilidade nos resultados dos tratamentos e à janela terapêutica limitada. A reabilitação, por sua vez, é um campo que continua a apresentar oportunidades de inovação, com destaque para o uso de novas tecnologias, como estimulação elétrica e realidade virtual, que têm demonstrado eficácia na recuperação motora e cognitiva. Para garantir a continuidade dos avanços, é fundamental o investimento em mais estudos clínicos, que possam otimizar as abordagens terapêuticas e promover um tratamento mais personalizado e eficaz, além de uma integração ainda mais eficaz entre as diversas especialidades envolvidas no cuidado ao paciente com AVCi.
PROTAGONISMO DA EQUIPE DE ENFERMAGEM NOS CUIDADOS AOS IDOSOS ASSISTIDOS PELA ATENÇÃO PRIMÁRIA À SAÚDE: REVISÃO INTEGRATIVA
Authors: Dias Luciene Teixeira , Silva Patrick Leonardo Nogueira da , Dias Jannayne Lúcia Câmara , Costa Amanda de Andrade , Santos Claudio Luís de Souza , Rabelo Jonathan José Damon Alves , Martins Aurelina Gomes e , Freitas Ingred Gimenes Cassimiro de , Ruas Rosana Franciele Botelho , Souto Simone Guimarães Teixeira , Siqueira Leila das Graças , Alves Carolina dos Reis
Published: February 2025

Este estudo objetivou discutir sobre o protagonismo da equipe de enfermagem nos cuidados aos idosos assistidos pela Atenção Primária à Saúde. Trata-se de uma revisão integrativa da literatura, realizada nas bases de dados online da Biblioteca Regional Médica, sendo elas: Medical Literature Analysis and Retrieval System Online, Literatura Latino-Americana e do Caribe em Ciências da Saúde e a Base de Dados de Enfermagem. A amostra do estudo foi constituída por 14 artigos científicos publicados durante o período de 2017 a 2022. A coleta dos artigos foi realizada durante o 1º semestre de 2022, nos meses de março e abril, pelo pesquisador responsável. Os achados do estudo foram representados em uma tabela e discutidos a luz da literatura científica. Observou-se que o autogerenciamento pela equipe de enfermagem dos recursos disponíveis à população idosa, bem como a utilização do círculo de cultura como intervenção educativa na promoção da saúde de idosos com doenças crônicas, configuram as principais ferramentas gerenciais, organizativas e assistenciais da enfermagem mais discutidas nos estudos já publicados. Ainda, os estudos abordam a preocupação da equipe de enfermagem com o acesso e a acessibilidade do idoso à Unidade de Saúde da Família e a realização de visitas domiciliares para a busca ativa, bem como com a realização de testes de cognição de idosos quanto ao acompanhamento de sua saúde mental. Portanto, conclui-se que o protagonismo da enfermagem se faz por meio da assistência ativa pela equipe, bem como do seu autogerenciamento, com impacto direto na saúde da pessoa idosa tendo em vista a prevenção de doenças crônicas e degenerativas, a redução consideravel da necessidade de cuidados intensivos e aumento da sobrevida e da qualidade de vida do idoso.
Analysis of approaches to repair and restoration of worn friction surfaces of ceramic matrix brake discs
Authors:   Vorobev A. A. Nilov A. S. CHayka E. S.
Published: February 2025

To assess the current level and approaches to repair and restoration of worn brake surfaces of automobile brake discs made of ceramic matrix composites (CMC) with a SiC matrix. The analysis of technological processes for repair work and restoration of worn coatings of two types of CMC brake discs was carried out. It was revealed that there are currently four basic technologies for repair and restoration of CMC brake discs, each with its own advantages and disadvantages. For these technologies, their features were considered and priorities were determined for their selection when carrying out repair work for specific types of defects in brake surfaces and various types of CMC brake discs. It was shown that the use of repair and restoration work makes it possible to significantly extend the service life of such an expensive element of the automobile braking system as a CMC brake disc.

Keywords
ceramic matrix composite, surface defects, friction surface repair, LSI technology, LPI technology, high-temperature soldering, flame spraying
Creation of an unmanned robotic platform as a way to solve a number of utility tasks
Authors:   Grajdantsev E. V. Gubar O. N. Ahpashev A. YU. Aliev D. A. Leskov V. D.
Published: February 2025

The article considers a number of aspects affecting the possibility of organizing work on the design and creation of unmanned utility technological platforms and the integration of such systems into the urban environment, the mass and dimensional characteristics of technological platforms, algorithms for the functioning of basic control systems, positioning elements, sensors and additional equipment for the organization of machine vision.

Keywords
vehicles, unmanned vehicles, utility vehicles, unmanned platforms
On increasing the capacity of the Voronezh city street and road network
Authors:   Zelikova N. V.
Published: February 2025

The stages of traffic management in the perspective of the use of unmanned road transport on the street and road network of large cities are considered, the results of visual observations of the movement of single cars and traffic flow in general are presented, shortcomings in the organization of traffic are identified, the causes of starting delays at intersections are determined. A variant of the order of access to a regulated intersection and exit from it by motor transport is considered. It is proposed to fix such a variant of the passage of a regulated intersection in the Traffic Rules of the Russian Federation. It is proposed to make changes and additions to paragraph 6.14 of the Traffic Rules of the Russian Federation.

Keywords
road network, vehicle, road intersection, left turn, starting delay
Problems of traffic intensity growing in Yakutsk city and ways of their solution
Authors:   Filippova N. M. Boyarshinov A. L. Filippov D. V.
Published: February 2025

The socio-economic development of Yakutsk in recent decades has been accompanied by an increase in the population of the agglomeration with a simultaneous increase in its motorization rate. The existing transport and logistics delivery scheme has radically changed as a result of the railway construction to the village of Nizhny Bestyakh. It is generally accepted that one of the main positive effects of the planned bridge crossing over the Lena River will be the elimination of seasonal gaps. The bridge will also cause dramatic changes in the directions of traffic flows in the urban agglomeration, and can lead to congestion of the road network, its accelerated wear and tear and a decrease in road safety. The likely negative impact of the bridge remains poorly understood and dictates the need to analyze the capabilities of the road system and adjacent territories for the redistribution of traffic flows and transit of goods after the bridge occurrence. The article highlights the main problems and proposes individual measures to solve them. The article was published with the support of the REC "North — territory of sustainable development".

Keywords
transport, traffic intensity, traffic flow, road network, motorization of the population, transit potential
Calculation of parameters of electric starter system of internal combustion engine using a ready-made starter
Authors:   Volkov E. V.
Published: February 2025

When designing a self-starting power supply system, it is necessary to study the possibility of using an existing starter from another model of a car or tractor on a new engine. This task also becomes relevant in the case of developing a series of engines with different working volumes for one basic model of automotive and tractor equipment. In order to unify storage batteries and starters, it is advisable to reduce their nomenclature, ensuring compliance with the requirements of regulatory documents.

Keywords
nominal capacity of the storage battery, nominal power of the starter, volt-ampere characteristic, electromechanical and mechanical characteristics of the starter, torque resistance to cranking, minimum starting temperature, minimum starting frequency of the engine, gear ratio of the drive
Exploring the Key Drivers of Employee Performance: A Comprehensive Study of Contributing Factors
Authors: Roul Abhijeet , Dash Rutuparna
Published: February 2025

Focusing on company culture, leadership style, job satisfaction, training opportunities, and work-life balance, this article looks at the factors influencing employee performance. Using these components, it looks at the relationships among demographic factors—age, gender, tenure. Combining ideas from Maslow's Hierarchy of Needs and Herzberg's Two- Factor Theory, the studies reveal a whole picture of motivating elements and performance enhancement. It emphasizes the need of good leadership, motivating surrounds of work, and continuous professional development. The study also covers problems including stress, burnout, and inadequate resources by way of properly written guidelines and treatments. The study provides relevant information to legislators and human resource managers by use of statistical tools including correlation analysis and regression study. The outcomes underscore the need of tailored planning that fits both personal and business goals. The study contributes to the larger general discussion on environmentally friendly HR practices, employee welfare, and business fairness. Emphasizing health, empowerment, and lifetime learning, it challenges a strategic assessment of accepted management practices. Employee performance is a dynamic process influenced by organizational, personal, and outside elements calling for a proactive combined approach to human resource management.
STABILITY TESTING OF PHARMACEUTICAL PRODUCTS
Authors: Saloni Baria  , Khushi Koli  , Riyansi Koli  , Muskan Dhodi
Published: February 2025

Stability testing is a crucial part of the pharmaceutical development process that ensures the safety, efficacy, and quality of a drug product throughout its shelf life. This testing involves subjecting the product to various environmental condition, such as temperature, humidity, and light, to evaluate how these factors affect its physical, chemical, and microbiological properties. Stability studies help determine the appropriate storage conditions, expiration date, and packaging requirements for a pharmaceutical product. The tests are typically conducted under accelerated, intermediate, and long-term conditions, with samples analyzed at predefined intervals. The data obtained from stability testing also play a critical role in a regulatory approval process, providing evidence that the product remains within specifications throughout its intended shelf life. Furthermore, stability testing is an ongoing process that continuous post-market to monitor any potential changes or degradation that may occur during distribution or consumer us. This paper reviews the principles, methodologies, and importance of stability testing, highlighting its role in ensuring the reliability of pharmaceutical products in the market.
KEYWORDS: Stability testing, ICH Guideline, Shelf life
THE TURKIC-MONGOLIC LEXICAL PARALLELS AND LEXEMES FROM OTHER LANGUAGES IN THE OLD UZBEK LITERARY TRANSLATION OF “ZAFARNOMA”
Authors: Primov Azamat Iskandarovich
Published: February 2025

The article discusses the genealogical characteristics and distinctive usage aspects of Turkic-Mongolic lexical parallels and lexemes from other languages found in the Old Uzbek translation of Zafarnoma, originally written in Persian by Sharafuddin Ali Yazdi in 1424–1425 (Hijri) and translated into Old Uzbek by Muhammad Ali ibn Darvesh Ali al-Bukhari in 1519.
KEY WORDS: Sharafuddin Ali Yazdi, Zafarnoma lexicon, Old Uzbek literary language, linguistic stratigraphy, lexical layers, genealogical analysis, Turkic-Mongolic lexical parallels, Chinese loanwords, Indian loanwords.
ONTOLOGICAL BASIS AND ECONOMIC ESSENCE OF STRATEGIC INNOVATIONS IN THE CONTEXT OF THE LIFE AND OPERATIONAL CYCLE OF CONSTRUCTION ENTERPRISES
Authors: Chupryna K.M. , Matveev V.V. , Alekseenko V.O. , Nikolayko D.M.
Published: February 2025

Abstract. In the context of the dynamic development of the construction market, strategic innovations play a crucial role in ensuring the competitiveness of enterprises. This abstract explores the ontological foundation and economic essence of strategic innovations within the life and operational cycles of construction companies. Defining strategic innovations, their role, and their impact on various stages of a company's life cycle is essential for achieving sustainable development. The life cycle of construction companies includes stages from ideation and design to the implementation and completion of construction, as well as the subsequent operation of facilities. Strategic innovations introduced at each of these stages can significantly enhance resource management efficiency, optimize processes, and ensure flexibility in responding to market changes.
In our work, we analyze how strategic innovations interact with the economic aspects of construction enterprises. The study examines the impact of innovations on productivity enhancement, cost reduction, improvement of service quality and competitiveness, as well as the formation of new business models. Special attention is given to the analysis of risks and uncertainties associated with the implementation of innovative strategies and their effect on the life cycle of enterprises.
In particular, strategic innovations may include the introduction of new technologies, management approaches, construction methods, as well as changes in the processes of interaction with clients and suppliers. Innovative strategies not only improve internal operational processes but also enable construction companies to adapt flexibly to changes in market conditions. The research also highlights the importance of investing in innovations to develop human capital, improve staff qualifications, and create conditions for high labor productivity.
Thus, the study of the ontological foundation and economic essence of strategic innovations reveals their potential in achieving success in the construction market, which is crucial for the further development of the industry and ensuring its sustainability.
DIGITAL OPERATIONAL ECOSYSTEMS OF CONSTRUCTION ENTERPRISES: SMART MANAGEMENT, ADAPTATION, AND TRANSFORMATION
Authors: Khomenko O. , Chernenko M. , Krupnyk D. , Kushnir O. , Davydenko O. , Pereli D.
Published: February 2025

Abstract. The modern construction industry is undergoing an active process of digital transformation, driven by the need to enhance management efficiency, optimize resources, and reduce costs. This article examines the economic and managerial aspects of digital transformation in the construction sector, focusing on key concepts and best practices for implementing innovative solutions. SMART management of construction projects is analyzed as the foundation of the operational activities of construction enterprises, based on the integration of digital technologies, IoT solutions, artificial intelligence (AI), and Big Data to improve productivity, automate processes, and enhance decision-making systems. The study emphasizes adaptive platforms as a key element of the digital ecosystem in construction development. The use of adaptive platforms enables the integration of BIM modeling, digital twins, and blockchain technologies, ensuring process transparency, real-time control, and reduced project implementation time. The impact of digital tools on stakeholder management efficiency, supply chain optimization, and risk minimization in construction is also analyzed. The article identifies the economic imperatives of digital transformation in the operational systems of construction enterprises, including transaction cost reduction, increased investment attractiveness of projects, optimization of material resource utilization, and the implementation of sustainable development models. A systematic approach to digital construction management is proposed, based on the integration of flexible business models, smart monitoring technologies, and analytical forecasting tools. The study proves that digital transformation in the construction industry is not only a technological advancement but also an economic factor that enhances the competitiveness of enterprises. Successful cases of SMART management implementation in construction are presented, key challenges of digitalization are outlined, and recommendations for improving economic and managerial mechanisms in the construction sector are formulated.
National Allegory Through Her Own Voice: A Reading of Wangari Maathai’s Unbowed: One Woman’s Story
Authors: Ogaro Gladys Nyaiburi , Ndogo Samuel Macharia
Published: February 2025

This paper examines Wangari Maathai's Unbowed: One Woman’s Story as a national allegory, exploring its portrayal of Kenya's socio-political and cultural identity. Anchored on Hall’s theory of the nation as a site of inclusion and exclusion, the study foregrounds Maathai’s articulation of Kenya’s gendered nationhood. Further drawing on the theoretical postulations of Butler, McClintock, and Yuval-Davis, the paper interrogates how Maathai critiques patriarchal structures and the instrumentalization of women in national narratives. Her story intertwines personal struggles with national challenges. Her marriage and subsequent divorce reflect Kenya's tumultuous journey through independence and post-independence disillusionment. Through the lens of orature, Maathai revisits Kikuyu myths, colonial disruptions, and postcolonial challenges, revealing the interplay of gender, power, and nationalism. Maathai's leadership, grounded in her Anjiru clan heritage, underscores her unwavering commitment to national development through political, environmental, and social activism. Despite setbacks in politics and personal life, she emerges as a resilient figure, confronting issues such as ethnic division, governance failures, and environmental degradation. Maathai’s autobiographical reflections on identity, social justice, and environmental activism underscore her resistance against colonial and neo-colonial legacies. This allegorical reading posits Unbowed as a narrative of Kenya’s ongoing struggle for equality, inclusivity, and self-determination. Using metaphors such as the African stool with three legs (democracy, sustainable resource management, and peace), Maathai offers a blueprint for a just and sustainable Kenya. Her story celebrates persistence, hope, and collective responsibility in the quest for nation-building, providing a powerful feminist and nationalist perspective.
Justificações da adoção do enfoque territorial nas políticas públicas rurais
Authors: Schiesari Carolina , Moruzzi Marques Paulo Eduardo
Published: February 2025

Este estudo tem o objetivo de identificar as justificações e suas formas de comprovações em torno do processo de adoção da abordagem territorial de desenvolvimento para o meio rural brasileiro e baiano. A Teoria das Justificações é o principal referencial teórico-metodológico utilizado para a análise dos discursos de representantes dos poderes executivos nacional e estadual em termos de suas estratégias. Posteriormente, com a finalidade de avaliar a aplicação da principal política territorial em andamento no Brasil, aquela de Desenvolvimento Territorial do estado da Bahia, a avaliação se dirigiu aos discursos dos atores locais com a mesma base teórica.  Como resultado, elementos da ordem de justiça cívica, como bem-estar comum, inclusão social, governança participativa, ação coletiva e mobilização social, situam-se na base destas construções discursivas visando legitimação a favor do enfoque territorial. Por outro lado, comprovações de vontade política, engajamento social e aplicação de dispositivos legais robustos se mostraram essenciais para possibilitar a continuidade e o avanço desta perspectiva, fatores consistentes no estado da Bahia, porém enfraquecidos a nível nacional. Entretanto, quanto a sua efetividade, a política territorial da Bahia enfrenta importantes desafios, sobretudo no que diz respeito à promoção da intersetorialidade, questão que demanda maiores estudos para a sua validação.
Multi-Objective Ant Lion Optimizer for Congestion Management and Real-Power Rescheduling in Power Systems
Authors: Ziane Ismail , Benhamida Farid , Graa Amel
Published: February 2025

This paper presents the congestion management problem in electrical networks during power line outages and overloads on other lines. The study focuses on congestion management in the IEEE 30 bus system and modifies the IEEE 30 bus system by applying a model for congestion management pricing, incorporating data from both transmission lines and generators. The research proposes a Multi-Objective Ant Lion Optimizer (MOALO) method to solve single and multi-objective optimization problems to find a solution for management pricing, comparing results with other research methods to show the effectiveness of the applied approach and the mathematical model representing congestion management.
Application of Neural Network Algorithms in Networked Microgrids' Operation Optimization and Control
Authors: Rehman Muhammad Atiq Ur , Rivera Sergio , Abdullah Suheel , Khan Muhammad Sajjad
Published: February 2025

Neural Network algorithms have significant applications in microgrid operations optimization and control to provide cheap, robust, and reliable energy to end-users. These algorithms are inspired by artificial neural networks (ANNs). In this paper, we have proposed a neural network algorithm (NNA) based on the unique structure of ANNs. Neural network algorithms have the capability to generate new candidate solutions using the complicated structure of ANNs and their operators. Improvised exploitation and each parameter in the asymmetric interval are iteratively converged theoretically in the context of convergence proof. In this paper, we have demonstrated the scheduling problems for networked microgrids solved by using artificial neural networks (ANNs) along with the biological nervous systems approach. The neural network algorithm (NNA) is designed by using a specific structure of ANNs. NNA has the capability to take the benefits using complicated structure of ANNs to generate the enhanced solution. The designed code supports and implements a neural network-supported optimization algorithm. The proposed algorithm finds optimal solutions by utilizing solutions that are based on certain rules produced by machine learning neural networks.
An Optimal Landing Problem for a Bessel Process
Authors: Lefebvre Mario
Published: February 2025

A homing problem for a one-dimensional Bessel diffusion process is considered. The aim is to bring the controlled process to a value representing ground level as quickly as possible while taking the control costs into account. The cost function includes a parameter that takes the risk sensitivity of the optimizer into account. An explicit solution is found for both the value function and the optimal control in a particular problem.
The Concept of Expectation in Behavioral Finance Theory: A Bibliometric Analysis
Authors: Kurt Unzule , Caliskan Zehra Dogan
Published: February 2025

Behavioral economics is a subfield of economics that reveals how individuals' economic decisions are influenced by cognitive, emotional, and psychological factors. In behavioral economics, individuals are not only seen as actors who interpret economic indicators and make rational decisions but they are also considered in terms of their emotions and motivations. Therefore, behavioral economics investigates how certain emotional and psychological motivations affect economic decisions. Behavioral finance theory, from the same perspective, examines the financial decisions individuals make within the context of psychological and emotional variables. In behavioral finance theory, the most important emotional determinant is the concept of "expectation." In this context, the study investigates how the concept of "expectation" is addressed in studies examining the field of behavioral finance theory using the bibliometric analysis method. This research examines databases such as Web of Science, Scopus, and Google Scholar between the years 1985-2022, based on criteria such as the number of publications, citations, leading authors, countries, and institutions, aiming to reveal the evolution of the concept of expectation over time. In this regard, the study finds that the effects of the concept of expectation in behavioral finance theory have been examined more frequently since the 2000s. These studies primarily focus on risk perception and loss aversion behaviors.
Endoscopic treatment outcome of oesophageal gastrointestinal stromal tumours
Authors: Xu En-Pan , Qi Zhi-Peng , Zhang Jia-Wei , Li Bing , Ren Zhong , Cai Ming-Yan , Cai Shi-Lun , Lv Zhen-Tao , Chen Zhang-Han , Liu Jing-Yi , Zhong Yun-Shi , Zhou Ping-Hong , Shi Qiang
Published: February 2025

BACKGROUND

There are few clinicopathologic characteristics and clinical results for oesophageal gastrointestinal stromal tumours (GISTs). Thus, the objective of this study was to identify the clinicopathologic characteristics and clinical results of oesophageal GISTs.

AIM

To investigate endoscopic treatment effective of oesophageal GISTs.

METHODS

It was retrospective research that collected 32 patients with oesophageal GISTs treated by endoscopic resection (ER) between January 2012 and January 2023 in two Hospital. Clinicopathologic, endoscopic records, and follow-up data were collected and analysed.

RESULTS

Thirty-one patients underwent en bloc resection and 24 (75.0%) lesions underwent R0 resection. The size of GISTs was 2.12 ± 1.88 cm. The overall complication rate was 25.0%, including hydrothorax and post-endoscopic submucosal dissection electrocoagulation syndrome. The mean mitotic index was 3.34 ± 5.04 (median, 1.50; range, 1.00-4.00). Eighteen (56.3%), 6 (18.8%), 2 (6.3%), and 6 (18.8%) patients were identified as very low, low, intermediate, and high risk, respectively. Three patients developed recurrence after a median follow-up of 64.69 ± 33.13 months. The 5-year overall survival rate was 100%, and the disease-free survival rate was 90.6%.

CONCLUSION

ER is safe and effective for patients with low-risk oesophageal GISTs. Early detection of oesophageal GISTs is essential to achieve a favourable prognosis.
Tenofovir amibufenamide: A potential alternative for chronic hepatitis B treatment
Authors: Ma Hai-Nan , Cao Kai-Sen , Liu Yan-Miao , Chen Cheng , Zhang Hang , Tang Fu-Shan
Published: February 2025

Tenofovir amibufenamide (TMF) is a novel prodrug of tenofovir that demonstrates a promising safety and efficacy profile. A recent study by Peng et al compared TMF with tenofovir alafenamide in the treatment of chronic hepatitis B. The findings indicated that both medications offer similar efficacy in terms of viral response and alanine aminotransferase normalization. Notably, TMF showed potential advantages in lipid management, as it did not significantly affect cholesterol levels, unlike tenofovir alafenamide. This correspondence highlights the need for further research to evaluate the long-term safety and efficacy of TMF, its impact on cardiovascular risk, and its use in specific patient populations.
Artificial intelligence in gastroenterology: Ethical and diagnostic challenges in clinical practice
Authors: Ramoni Davide , Scuricini Alessandro , Carbone Federico , Liberale Luca , Montecucco Fabrizio
Published: February 2025

This article discusses the manuscript recently published in the World Journal of Gastroenterology , which explores the application of deep learning models in decision-making processes via wireless capsule endoscopy. Integrating artificial intelligence (AI) into gastrointestinal disease diagnosis represents a transformative step toward precision medicine, enhancing real-time accuracy in detecting multi-category lesions at earlier stages, including small bowel lesions and precancerous polyps, ultimately improving patient outcomes. However, the use of AI in clinical settings raises ethical considerations that extend beyond technological potential. Issues of patient privacy, data security, and potential diagnostic biases require careful attention. AI models must prioritize diverse and representative datasets to mitigate inequities and ensure diagnostic accuracy across populations. Furthermore, balancing AI with clinical expertise is crucial, positioning AI as a supportive tool rather than a replacement for physician judgment. Addressing these ethical challenges will support the responsible deployment of AI, through equitable contribution to patient-centered care.
Circular RNA contributes to gastric cancer by targeting Wnt family member 2B as a competing endogenous RNA
Authors: Bai Wei , Guo Zong-Liang , Guo Jiang-Hong , Li Feng , Bu Peng , Liu Juan
Published: February 2025

BACKGROUND

As a non-coding RNA molecule, circular RNAs (circRNAs) have significant specificity, and existing data suggest a close relationship between them and the prognosis of patients with gastric cancer (GC). However, this mechanism has no evidence yet. This article explores the functions of hsa_circRNA_102415 in the malignant behavior and potential downstream signaling of GC cells. The chosen approach is loss of signal and functional gain.

AIM

To investigate and analyze the relationship between hsa_circRNA_102415 and GC and explore its specific role. Results provide reference for other researchers to develop targeted treatment plans.

METHODS

The gene expression omnibus (GEO) database can be used to obtain the microarray dataset GSE83521. Data were analyzed using the GEO2R tool to identify differences in circRNAs between normal and GC samples. Quantitative real-time polymerase chain reaction was used to detect differentially expressed genes in GC tissue samples and adjacent cancer tissue samples. GC cells were transfected with small interfering-hsa_circRNA_104415 and plasmid DNA (pcDNA)-hsa_ircRNA_102415. Multiple detection methods, such as Transwell and cell counting kit 8, were used to evaluate cellular physiological activities, including cell invasion and proliferation. The relationship between Wnt family members 2B, microRNA (miR)-4529-5p, etc. , including argonaute 2-RNA immunoprecipitation and luciferase reporter genes was analyzed. Rescue experiments were conducted to analyze and explore the relationship between the malignant behavior of GC cells and hsa_circRNA_102415.

RESULTS

GEO2R analysis confirmed that hsa_circRNA_102415 had significantly higher expression levels in disease tissues. hsa_circRNA_102415 and miR-4529-5p showed a negative correlation in disease cells, suggesting that hsa_ circRNA_102415 upregulated WNT2B expression in GC cells as a competing endogenous RNA for miR-4529-5p. miR-4529-5p mimic or small interfering-WNT2B reversed the effects of pcDNA-hsa_circRNA_102415 or miR-4529-5p inhibitor on cell malignant functions.

CONCLUSION

miR-4529-5p was used to successfully activate the potential of WNT2B , clarify the role of hsa_circRNA_102415 in GC cells, and provide reference for other researchers to develop targeted treatment plans.
Review of theoretical approaches to the formation of innovative infrastructure for the development of the service sector
Authors:   Siberian Federal university, Byvshev V. I. , Suslova Yu. Yu. ,   Siberian Federal university, Voloshin A. V. ,   Siberian Federal university, Pisarev I. V. ,   Krasnoyarsk Regional Fund of Science and Technology Support
Published: February 2025

Introduction. The development of theoretical approaches to the formation of innovative infrastructure is currently considered as one of the ways to achieve technological sovereignty. The service sector is one of the areas of modern economy that can provide potential GDP growth and has the potential for innovative development.

Goal. Formation of a theoretical approach to the definition and composition of the elements of the innovative infrastructure for the development of the service sector.

Materials and methods. The research materials were scientific publications on the subject of the work of domestic and foreign authors. The research uses formal logical and general scientific methods, as well as a descriptive method.

Results and discussion. Approaches to the formation of innovative infrastructure are studied, a typology of approaches to the formation of innovative infrastructure is compiled. The composition of the types of elements of the innovative infrastructure of the service sector is determined, which identifies two types of elements proposed by the authors in comparison with existing approaches, the digital type of elements and the social one. The definition of the concept of innovative infrastructure for the development of the service sector is given.

Conclusion. The approaches to the concept of innovation infrastructure vary depending on its scale. The innovation infrastructure of individual spheres should include specialized types of elements that will contribute to the innovative development of this particular sphere, and over time, new types of elements may form depending on the vector of innovative development of the sphere.
The study of synchronization accuracy of ENMU devices according to the PTPv2 protocol in laboratory conditions
Authors:   North-Caucasus Federal University, Kononov Yu. G. , Zvada P. A. ,   North-Caucasus Federal University, Zelenskii E. G. ,   North-Caucasus Federal University, Zvezdilin R. A. ,   North-Caucasus Federal University, Turchenko D. A. ,   North-Caucasus Federal University
Published: February 2025

Introduction. One of the directions of digital transformation of the electric power industry is the introduction of intelligent electronic devices (IED) with the function of synchronized measurements. For high-precision and reliable synchronization of the IED, the PTPv2 protocol is used in combination with fiber-optic communication lines (FOCL) and programmable switches supporting them. There is experience of such synchronization at distances up to 2 km in substation projects with a high level of automation. However, there is no experience of practical testing of such a solution in distribution networks at distances of more than 2 km based on ENMU devices of Energoservice LLC.

Goal. The aim is to study the accuracy of synchronization of ENMU devices using the PTPv2 protocol of the IEEE 1588 standard using a timeserver, telecommunication switches and media converters and an 8 km fiber-optic communication line in laboratory conditions.

Materials and methods. The study was performed in laboratory conditions using a time correction unit, an industrial switchboard and a media converter, a bay with an 8 km long OKP-K-8 fiber-optic cable, a reference signal generator and a backup measuring system based on National Instruments measuring devices implementing the PMU functionality.

Results and discussion. The results of laboratory tests showed that the synchronization accuracy ranged from 0.5 to 16 µs, depending on the method used to calculate the desynchronization.

Conclusion. Laboratory tests have shown the possibility of synchronizing measurements with high accuracy using ENMU devices based on the IEEE 1588 PTP v2 protocol at a distance of at least 8 km. The results obtained prove the prospects for the introduction of such devices not only in power supply centers, but also within the entire feeder of the distribution network or its individual parts.
Мodeling of electromagnetic effects of multicircuit power lines on pipelines
Authors:   Irkutsk State Transport University, Kryukov A. V. ,   Irkutsk National Research Technical University, Suslov K. V. ,   National Research University “MPEI”; Irkutsk National Research Technical University, Cherepanov A. V. ,   Irkutsk State Transport University, Kryukov A. E. ,   Irkutsk National Research Technical University, Batuhtin A. G. ,   Irkutsk National Research Technical University
Published: February 2025

Introduction. An effective way to reduce land allocation for the construction of power engineering facilities is to implement multi-circuit power lines (MCPL). In the medium term, it can be expected that in some areas these lines will be located near main pipelines; due to the electromagnetic influence on the parts of the structure, potentials may arise that are dangerous for personnel and negatively affect the corrosion protection systems. To solve the problem of calculating the effects of MCPL on pipelines, an approach based on phase coordinates can be effectively used.

Goal. To develop digital models for determining induced potentials and currents on a pipeline laid parallel to the route of a multi-circuit power line.

Research methods. Technologies for modeling the modes of electric power systems in phase coordinates were used.

Results and discussion. A comparison of a MCPL and a corridor of lines allowed the authors to formulate the following conclusions. In the normal mode the induced voltages at individual points of the pipe in the model with a multi-circuit power transmission line exceed similar indicators for the corridor of lines by almost two times. In an open-phase mode the potential ratios on the pipe for a MCPL and a corridor of lines are within the range of 0.7…2.44, and for currents 0.7…0.82.

Conclusion. The applied approach to calculation of induced voltages is universal and can be used to determine modes in networks of various configurations. The models presented in the article can be useful in the practice of designing sections of joint passage of promising multi-circuit power transmission lines and pipelines when planning measures to ensure the safe operation of service personnel. The scientific novelty of the presented results consists in the use of an original method for determining the electromagnetic effects of multi-circuit power transmission lines on pipelines, based on the use of phase coordinates. The method applies to multi-circuit power transmission lines of other designs, for example, four- and six-circuit.