bluuebunny/crossref_metadata_2025 huggingface dataset:
LITERATUR REVIEW : EFEKTIFITAS PENERAPAN TEKNIK RELAKSASI NAFAS DALAM TERHADAP PENURUNAN NYERI PADA PASIEN FRAKTUR
Authors: Vanika
Published: February 2022

Latar Belakang: Nyeri merupakan manifestasi penderita fraktur, Pada penderita fraktur rasa nyeri sering dirasakan sifat menusuk dan tajam yang ditimbulkan akibat spasme otot atau penekanan bagian saraf sensori, oleh karena itu nyeri yang tidak diatasi akan memperlambat masa penyembuhan atau perawatan. Tindakan yang dilakukan dalam penatalaksanaan mencakup tindakan farmakologi dan nonfarmakologi. Tindakan nonfarmakologis merupakan hal utama dalam beberapa kasus nyeri yang bersifat ringan diantaranya teknik relaksasi nafas dalam. Teknik relaksasi adalah proses mengendalikan emosi yang akan membuat tubuh menjadi rileks. Tujuan: Tujuan penelitian ini untuk mengetahui efektifitas tindakan teknik relaksasi nafas dalam terhadap penurunan nyeri pada pasien fraktur. Metode: keperawatan yang digunakan pada penelitian ini adalah literature review mengenai teknik relaksasi nafas dalam. Penelusuran artikel dilakukan dengan google search yang dipublikasikan sejak tahun 2016-2020 yang diakses fulltext dalam format pdf. Hasil : Berdasarkan kelima artikel jurnal yang telah dilakukan review maka menunjukkan bahwa penerapan teknik relaksasi nafas dalam dapat mengurangi nyeri pada pasien fraktur. Kesimpulan: Secara signifikan ditunjukan bahwa teknik relaksasi nafas dalam adalah teknik yang sangat efektif dalam mengurangi intensitas nyeri
Anomaly Detection applied to Money Laundering Detecion using Ensemble Learning
Authors: Otero Gomez Daniel , Agudelo Santiago Cartagena , Patiño Andres Ospina , Lopez-Rojas Edgar
Published: February 2022

Financial crime and, specifically, the illegal business of money laundering are increasing dramatically with the expansion of modern technology and global communication, resulting in the loss of billions of dollars worldwide each year. Money laundering, known as the process that transforms the proceeds of crime into clean legitime assets, is a common phenomenon that occurs around the world. Irregular obtained money is generally cleaned up thanks to transfers involving banks or companies, see Walker (1999). Hence, one of the main problems remains to find an efficient way to identify suspicious actors and transactions, in each operation attention should be focused on the type, amount, motive, frequency, and consistency with the previous activity and the geographic area. This identification must be the result of a process that cannot be based solely on individual judgments but must, at least in part, be automated. Although prevention technologies are the best way to reduce fraud, fraudsters are adaptive and, given time, will usually find ways to overcome such measures, see Perols (2011). Then, what we propose is to enrich this set of information by building an anomaly detection model in operations related to money transfer in order to benefit from the power of artificial intelligence. Now, antimoney laundering is a complex problem but We believe Artificial Intelligence can play a powerful role in this area.
Contrasting symbolic and non-symbolic numerical representations in a joint classification task
Authors: Prpic Valter , Basamh Yasmine , Goodridge Courtney Michael , Agostini Tiziano , Murgia Mauro
Published: February 2022

Both symbolic (digits) and non-symbolic (dots) numerals are spatially represented, with relatively small numbers being responded faster with a left key press and large numbers being responded faster with a right key press (Spatial-Numerical Association of Response Codes). The idea of a format independent SNARC seems to support the existence of a common system for symbolic and non-symbolic numerical representations, although evidence in the field is still mixed. The aim of the present study is to investigate whether symbolic and non-symbolic numerals interact in the SNARC effect when both information is presented simultaneously. To do so, participants were presented with dice-like patterns with digits being used instead of dots. In two separate magnitude classification tasks, participants had to respond either to the number of digits being present on the screen or to their numerical size. In the non-symbolic task, they had to judge whether the digits on the screen were more or less than three, irrespective of the numerical value of the digits. In the symbolic task, participants had to judge whether the digits on the screen were numerically smaller or larger than three, irrespective of the number of digits being present. The results show a consistent SNARC effect in the symbolic task and no effect in the non-symbolic one. More interestingly, congruency between symbolic and non-symbolic numerals did not modulate the response patterns, thus supporting the idea of independent representations and questioning some of the current theoretical accounts.
Are Changes in the Perception of Major Life Events Associated With Changes in Subjective Well-Being?
Authors: Haehner Peter , Pfeifer Lena Sophie , Fassbender Ina , Luhmann Maike
Published: February 2022

After experiencing a major life event, people differ in the extent and duration of event-related changes in subjective well-being (SWB). Some of these individual differences can be explained by individual differences in how people perceive major life events. But how events are perceived does not only vary between individuals, it also changes over time. We therefore examined the longitudinal interplay between perceived event characteristics and SWB using two short-term longitudinal studies conducted with German-speaking participants (NStudy1 = 619, 73% female; NStudy2 = 691, 71% female). In both studies, perceived event characteristics and SWB were assessed at two measurement occasions 3 months apart. We used bivariate latent change score models to estimate correlated changes of these constructs. Perceiving events as increasingly externally controlled and as increasingly social status threatening over time was consistently associated with a decrease in life satisfaction. Furthermore, perceiving events as increasingly challenging over time was consistently associated with a decrease in positive affect and an increase in negative affect. Our results indicate that the development of SWB and perceived event characteristics is intertwined, and they highlight the importance of assessing perceived event characteristics longitudinally to gain a better understanding of event-related changes in SWB.
Associations between ADHD symptoms and maternal and birth outcomes: An exploratory analysis in a multi-country cohort of expectant mothers
Authors: Murray Aja Louise , Taut Diana , Baban Adriana , Hemady Chad Lance , Walker Susan , Osafo Joseph , Sikander Siham , Tomlinson Mark , Du Toit Stefani , Marlow Marguerite , Ward Catherine , Fernando Asvini D , Madrid Bernadette , Vo Thang Van , Hoang Tuyen Dinh , Dunne Michael , Hughes Claire , Fearon Pasco , Valdebenito Sara , Eisner Manuel
Published: February 2022

ADHD symptoms can adversely impact functioning in a range of domains relevant for maternal well-being and foetal development; however, there has been almost no research examining their impact during pregnancy. We used data (n=1204) from a longitudinal birth cohort study spanning eight countries to address this gap. ADHD symptoms in the third trimester of pregnancy were associated with lower social support from family (b=-0.16, p=.031), friends (b=-0.16, p=.024), and significant others (b=-0.09 p=.001); higher stress (b=0.34, p<.001) and depressive symptoms (b=0.31, p<.001), and increased likelihood of an unwanted pregnancy (b=0.30, p=.009). Significant associations with tobacco use (b=.36, p=.023) and premature birth (b=.35, p=.007) did not survive correction for multiple comparisons and there were no significant associations with alcohol use, low birth weight, or unplanned pregnancy. Results suggest that women with ADHD symptoms could benefit from earlier, more regular screening for mental health difficulties and greater mental health support during pregnancy.
Reflexivity in Quantitative Research: a Rationale and Beginner’s Guide
Authors: Jamieson Michelle Kimberly , Govaart Gisela Hanna , Pownall Madeleine
Published: February 2022

Reflexivity is the act of examining one's own assumptions, beliefs, and judgments, and thinking carefully and critically about how these influence the research process. The practice of reflexivity confronts and questions who we are as researchers and how this guides our research. It is central in debates on objectivity, subjectivity, and the very foundations of social science research and generated knowledge. Incorporating reflexivity in the research process is traditionally recognized as one of the most notable differences between qualitative and quantitative methodologies. Qualitative research centres and celebrates participants’ lived experience, and qualitative researchers are readily encouraged to consider how their own positionalities inform the research process, forming an important part of qualitative research training. Quantitative methodologies in social and personality psychology, on the other hand, have remained seemingly detached from this level of reflexivity and general reflective practises. In this commentary, we, three quantitative researchers who have grappled with the compatibility of reflexivity with our research, argue that reflexivity has much to offer quantitative methodologists, in social and personality psychology and beyond. The act of reflexivity prompts researchers to acknowledge and centre their positionalities, encourages a more thoughtful engagement with every step of the research process, and thus, as we argue, contributes to the ongoing reappraisal of openness and transparency in psychology. In this paper, we make the case for integrating reflexivity across all research approaches, before providing a ‘beginner’s guide’ for quantitative researchers wishing to engage reflexivity within their work, providing concrete recommendations, worked examples, and reflexivity prompts.
ASSESSING SURVEY RESPONSE STABILITY A complementary quality assurance protocol for survey studies in the social sciences
Authors: Dolnicar Sara , Grün Bettina , MacInnes Sarah
Published: February 2022

Survey measurement scales are expected to be stable – to generate the same values across two timepoints and under unchanged conditions. In scale development, stability is assessed by calculating a scale’s test-retest reliability – a prerequisite to validity. Yet, a systematic review shows that test-retest reliability values are reported for only 23% of newly developed scales and typically assessed only at aggregate level – based on scale-level or subscale-level scores. This study (1) demonstrates how (sub)scale-level test-retest reliability indicators can conceal a lack of response stability at item level and (2) proposes a complementary protocol for assessing item-level response stability. Assessing stability at both item- and scale level ensures that only stable items are included in a scale, which, in turn, increases the reliability and validity of the scale and contributes to the replicability of findings in the social sciences.
EVALUACIÓN DEL PERFIL DE BIENESTAR Y CONTROL AMBULATORIO EN PACIENTES CON DIABETES MELLITUS TIPO 2 DEL PRIMER NIVEL DE ATENCIÓN EN LA UNIDAD DE MEDICINA FAMILIAR NO. 249, 2020
Authors: Ortiz-Vilchis Cristian Miguel
Published: February 2022

La diabetes mellitus tipo 2 o diabetes tipo 2 (DM2) se presenta como una interacción compleja entre genes y medio ambiente, caracterizada por hiperglucemia secundaria de una inadecuada secreción de insulina o inadecuada acción de la misma, por lo que la capacidad del organismo para autorregular la absorción y liberación de glucosa se ve alterada. La hiperglucemia prolongada es el principal contribuyente a las complicaciones micro y microvasculares de la DM 2 (1). La relevancia en priorizar esta enfermedad es que actualmente la diabetes y sus complicaciones se han convertido no solo en un grave problema de salud pública sino también en una gran carga económica y social para nuestras comunidades y está a punto de volverse un problema irresoluble (2). México es uno de los países a nivel mundial con la prevalencia más alta de DM2, en el Atlas 2017 de la Federación Internacional de Diabetes (3), se reporta una prevalencia nacional de 14.1%. De acuerdo a la Encuesta Nacional de Salud y Nutrición de Media Camino 2016 (51) la prevalencia de diabetes por diagnostico medico previo en México es de 9.4% lo que representa un incremento con relación a los datos obtenidos en la encuesta de 2006 de 7.34% y en la del 2012 de 9.2%, y la prevalencia reportada en mujeres es mayor (10.3%) que la encontrada en hombres (8.4%). La evidencia ha demostrado que el bienestar de los pacientes con diabetes se ve afectada de manera negativa requiriendo un abordaje sistemático de prevención ante la adopción de estilos de vida saludable, la detección oportuna y el establecimiento de programas efectivos tanto no farmacológicos como farmacológicos son estrategias efectivas y mejor aún costo-efectivas para disminuir la carga de la enfermedad metabólica y sus complicaciones. Objetivo. Evaluar el perfil de bienestar y el control ambulatorio en pacientes con diabetes mellitus del primer nivel de atención en la unidad de medicina familiar 249. Método: Estudio descriptivo observacional, prospectivo, transversal, donde se realizaron cuestionarios en base al instrumento DDS para evaluar el estado de bienestar, así como información obtenida en la consulta médica. Análisis: Se estudio una muestra de 98 pacientes con índice de confiabilidad de 97.5% de los cuales fueron 46 mujeres y 52 hombres, dividiendo la población en geriátrica y no geriátrica. Resultados: Se aplicó un análisis y prueba de chi cuadrada a ambas poblaciones para valorar la fuerza de asociación entre metas de control metabólico contra puntajes DDS, demostrándose un valor de p de <0.05 para la población no geriátrica, concluyendo en una asociación significativa.
Antibacterial activity profile and quality standards of Cymbopogon citratus Stapf- an aromatic grass used in Indian system of medicine
Authors:   Associate professor, Department of Dravyaguna, SDM College of Ayurveda, Kuthpady, Udupi, Karnataka-574118, India, Suma V Mallya , Tanuja Nesari ,   Professor and additional director, Brahmarshi Charaka Samsthana, New Delhi-110073, India
Published: February 2022

Background: Cymbopogon citratus stapf. an aromatic grass found cultivated commonly in India, used in ancient texts of Ayurveda to cure infectious diseases related to respiratory system. The aromatic, long leaves are major used part of this drug. Materials and methods: Leaves collected form mature plant, cleaned properly, macro-microscopic characters recorded as per standard methodology. Physico-chemical constituents and major secondary metabolites found in the leaves are marked. HPTLC fingerprints of methanolic extract of test drug drawn out. In vitro antibacterial activity of aqueous and methanolic extract of test drug carried out as per disc diffusion method, zone of inhibition measured. Results: Macro-microscopic characters, physicochemical standards are a measure of its quality. Secondary metabolites like triterpenoids, tannins, flavanoids etc revealed its chemical nature. HPTLC fingerprint further prove its chemical nature. Both methanolic and aqueous extract of the drug has shown sensitivity against all four bacterial strains. Conclusion: Methanoilc extract of test drug has shown better zone of inhibition against S. pyogen, S. aureus, P. auregenosa, thus proved a promising source of antimicrobial drug.
Quality Control Parameters of Arogyavardhini Rasa prepared by classical method
Authors:   Ph.D.(Ayu) Scholar, Dept. of Rasashastra & Bhaishajya Kalpana, I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar-361008, Gujarat, India, Sapkota Yuga Raj , Bedarkar Prashant ,   Asst. Prof, Department of Rasashastra and Bhaishajya Kalpana, I. P. G. T. and R. A, Jamnagar, Gujarat, India, Shukla V.J. ,   Head, Dept. Pharmaceutical Chemistry, I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar-361008, Gujarat, India, Prajapati P.K ,   Professor and Director, I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar-361008, Gujarat, India
Published: February 2022

Background: Arogyavardhini Rasa (AVR) is a well-known An Ayurvedic herbo-mineral formulation, indicated for treatment of broad spectrum chronic diseased conditions commonly used by physicians whose details of pharmaceutical processing are yet to document. Current research is first effort to document quality control parameters of this important formulation. Aim: To study the Pharmaceutical and physicochemical Quality Control Parameters profiles of Arogyavardhini Rasa. Materials & Method: AVR was prepared in one pilot and 3 main batches as per classical reference of Rasaratnasamucchaya. Its Physico-chemical parameters, qualitative tests for functional groups, Chromatography and quantitative elemental estimation were investigated. Results & Discussion: An average of 2500ml Swarasa was required for optimum Mardana for preparation of AVR from Avg. 506 gms of powdered Raw drugs, leading to an average yield, % yield (as that of powdered drugs) % wt gain of 605gm, 119.56%, 99 gm and 19.56% respectively. Functional groups Cardiac Glycosides, Alkaloids, Tannins and Phenols, Proteins, carbohydrates, steroids, Flavanoids, Saponins, Amino acids, Starch and Sugar were present. HPTLC study revealed a total of 11 and 8 bands at 254 nm and 366 nm in AVR. Conclusion: There is uniformity among results of observed and test parameters, among 3 batches. Pharmaceutical process, Results of pharmaceutical study, Physico-chemical tests, Presence of functional groups and HPTLC profile in present study may be considered as Standard manufacturing process of Arogyavardhini Rasa.
Efficacy of Pushpadhanva-Rasa and Svayamagupta-Ikshuraka Beeja Choorna on Ksheena-Shukraka (Oligozoospermia)
Authors:   Assistant Professor, Department of Roga Nidana & Vikriti Vijnana, I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar, Gujarat-361008, India, Pandya Darshna , Padariya Jitesh ,   Medical Officer, Indian Systems of Medicine and Homoeopathy (ISM&H), At Dhalaja, Surendranagar, Gujarat, India
Published: February 2022

Progeny is a dream for every couple, childlessness affects couples psychological harmony, sexual life and social functioning too. Among total infertility cases male infertility is as chief cause in 26.2 – 46.6% and the most common reason for male infertility is Oligozoospermia. The condition resembles with Ksheena Shukra described in Ayurveda. Vajeekarana- one of specialty of Ayurveda deals with such problems and can contribute substantially to solve this problem. Aim: To study the efficacy of Pushpadhanva-Rasa and Svayamagupta-Ikshuraka Beeja Choornaon patients of ologozoospermia. Materials and Methods: Patients having complaints of oligozoospermia were selected and treated with either of the drugs. Patients of Group-PR were given Pushpadhanva-Rasa 250mg tablet, twice a day with Ghee, whereas patients of Group-SI were given Svayamagupta-Ikshuraka Beeja Choorna 3 gm powder twice a day. In both the groups sugar added milk was kept as Anupana. Duration for the treatment course was one month. Result: Both therapies provided good improvement in different seminal as well as sexual parameters. Conclusion: In quantitative abnormality and disturbance in sexual parameter Pushpadhanva Rasa is better while Svayamagupta-Ikshuraka Beeja Choorna showed better results to improve quality of semen and level of testosterone.
Need of modifications in current trends in clinical researches in Ayurveda
Authors:   Associate Professor, Department of Kayachikitsa, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University (IMS-BHU), Varanasi, Uttar Pradesh-221005, India, Prasad Rajendra
Published: February 2022

Research and Innovations are the two necessary parts of any growing science. In innovations we make efforts to create something new whereas in researches we try to explore anything more from existing knowledge or information. Ayurveda is an independent science; principles and findings mentioned in this are well proved and experience based. Although there experiments were lacking but their approach and attitude about any concept was quite authentic and logical. It can be observed well if we consider the concept of indications of drugs; either in single form or as compound preparation. Especially the concept of “Rogadhikar” indicates the specific indication of any particular drug in any specific disease condition. Therefore while treating patients or planning research we can consider these drugs or preparations as standard drugs for particular condition. To make them more authentic or just to prove efficacy of those drugs, first we should plan researches and studies to validate them. If they found suitable and effective then we should consider or use them as standard or control drugs for conducting researches or clinical trials in ayurvedic medicine.
Concept of Embryology in Ayurved
Authors:   Assistant Professor, Department of Basic Principles, Faculty of Ayurveda, Parul University, Vadodara, Gujarat391760, India, Amin Hetal , Sharma Rohit ,   Assistant Professor, Department of RSBK, Abhilashi Ayurved Institute and Research Centre, Abhilashi University, Mandi, Himachal Pradesh-175002, India
Published: February 2022

The creation of the foetus is assured if the (1) a good seed is sown, (2) in a moist soil and (3) at the proper season, are presented combine in a proper manner. The creation of all beings is due to the proper union of the seed and field.[1] A woman here called Kshetra is really the best aphrodisiac and stimulant for procreation.[2] According to Chakrapani, a woman begets a stout son when all essentials viz. the uterus, the path of the ovum, the female and male seed, Vata and the mental state are normal and clear.[3]
Nutraceuticals in leukemia
Authors:   Department of Environmental Carcinogenesis & Toxicology, Chittaranjan National Cancer Institute, Kolkata, West Bengal- 700026, India, Roy Madhumita , Mukherjee Apurba ,   Department of Environmental Carcinogenesis & Toxicology, Chittaranjan National Cancer Institute, Kolkata, West Bengal- 700026, India, Mukherjee Sutapa ,   Department of Environmental Carcinogenesis & Toxicology, Chittaranjan National Cancer Institute, Kolkata, West Bengal- 700026, India, Biswas Jaydip ,   Director, Department of Environmental Carcinogenesis & Toxicology, Chittaranjan National Cancer Institute, Kolkata, West Bengal- 700026, India
Published: February 2022

The term Leukemia signifies cancer of the blood, bone marrow and lymphoid system and is resulted due to abnormal proliferation of immature white blood cells. Conventional therapeutic modalities for leukemia act by targeting various signalling pathways that contribute to leukemogenesis. These treatment strategies may be effective in tackling the disease but they often pose severe side effects as they harm the normal healthy cells along with the cancer cells. Thus alternative means of leukemia therapy need to be explored. Ayurveda, one of the ancient forms of medicine practised in the Indian subcontinent, may be a good option. Ayurveda aims to cure diseases by harnessing the power of natural herbs and other plant resources or phytochemicals. It has been documented that ayurveda is effective in the treatment of various types of cancer, including leukemia. These ayurvedic formulations may find their use as an adjuvant therapy in conjunction with existing treatment protocols. Ayurveda is unique in the way that it helps to control the disease in a non-toxic way by preventing growth of abnormal blood cells vis a vis sparing the normal cells. They also aid to relieve the leukemic patient of pain and anxiety in the later stages of the disease. Thus intense research is warranted to establish the potential of ayurveda or natural medicine in the therapy of leukemia.
Herbal approach to management of thyroid disease - a review
Authors:   Lab Tech. (Chemistry), Regional Ayurveda Research Institute for Metabolic Disorders, Ashoka Pillar, Jayanagar, Bangalore, Karnataka-560011, India, Bharthi Vandana , Kavya N ,   Senior Research Fellow (Ayurveda), Regional Ayurveda Research Institute for Metabolic Disorders, Ashoka Pillar, Jayanagar, Bangalore, Karnataka-560011, India, Shubhashree M. N. ,   Research Officer (Ayurveda), Regional Ayurveda Research Institute for Metabolic Disorders, Ashoka Pillar, Jayanagar, Bangalore, Karnataka-560011, India, Bhat Sulochana ,   Research Officer, S-3 (Ayurveda), Regional Ayurveda Research Institute for Metabolic Disorders, Ashoka Pillar, Jayanagar, Bangalore, Karnataka-560011, India
Published: February 2022

Endocrine disorders are common in India of which the thyroid disorders represent a major subset. Thyroid dysfunction prevalence is rising at an alarming rate in Indian population. Hypothyroidism and hyperthyroidism constitute the maximum percentage of thyroid diseases in India. Hormone replacement therapy has been a standard approach to thyroid dysfunction. However, herbal approach to treatment of thyroid dysfunction is gaining popularity as it is said to be equally effective, safe and devoid of any side effects. Ayurvedic system of medicine has been very effective in maintenance and treatment of hypothyroidism and hyperthyroidism. This review aims at providing comprehensive information regarding various herbal drugs used in Ayurveda acting towards correction of thyroid dysfunction.
Ayurvedic pharmacopea if constructed as per Ayurvedic principles; An observational outlook
Authors:   Associate Professor, Department of Dravyagauna, SDM College of Ayurveda, Udupi, Karnataka, India, V Mallya Suma , Madhusudhana Kamat ,   Associate Professor, Division of Ayurveda, Center for Integrative Medicine and Research (CIMR), Manipal, Karnataka, India, Sunilkumar KN ,   Research Officer, Siddha Central Research Institute, Central Council for Research in Siddha (CCRS), Chennai, Tamil Nadu, India
Published: February 2022

Natural products derived from plant, animal and mineral origin, constitute the materia medica of Ayurveda. Ayurveda, science of life has its own principles and theories in relation to cure of a disease or at maintenance of health. Quality monographs on these natural products constructed based on the principles of Ayurveda, may really serve the purpose in this regard. An observational discussion on facts and future scenario on Ayurveda pharmacopeia has been discussed in this paper.
Cirrhosis of liver: Review from Ayurvedic literature
Authors:   Senior Consultant (Ayurveda), Regional Ayurveda Research Institute for GID, Guwahati, Assam- 781028 India, Deka Darshana
Published: February 2022

Cirrhosis is the severe scarring of the liver and poor liver function seen at the terminal stages of chronic liver disease. The scarring is most often caused by long-term exposure to toxins such as alcohol or viral infections. It tends to progress slowly and often does not cause symptoms in its early stages. However,as the function of the liver gradually becomes worse, serious problems can develop. In Ayurveda, Yakrit is considered as an important anga right from the vedic period. Ayurvedic classical references are available regarding the enlargement of Yakrta. The disease Yakrddalyudara has been included in eight types of Udara Roga in Ayurvedic classics. In this article,an effort is made to understand the aetiopathogenesis, sign and symptoms Yakrddalyudara and its management mentioned in classical Ayurvedic texts along with its modern counterpart. There is no need to say that till date, no definite therapy is available in western system of medicine for the management of terminal diseases like cirrhosis of liver. Ayurvedic treatment seems to be very specific including pitta pacifying therapy and purificatory therapy.These measures mentioned in classics are also focused in this study which provide management in natural way with no adverse effects.
Management of alopecia by bloodletting and certain Ayurveda medicine: A case study
Authors:   Ph.D. Scholar, Department of Panchakarma, National Institute of Ayurveda, Jaipur, Rajasthan-302002, India, Bhusal Nirmal , Mangal Gopesh ,   Assistant Professor and Head, Department of Panchakarma, National Institute of Ayurveda, Jaipur, Rajasthan302002, India
Published: February 2022

Continuously increasing industrialization and urbanization has posed greater threat on health of hair due to pollution, contamination of water, air and stress. There is an increase in the incidence of Alopecia (Hair Fall). Alopecia can be correlated with Khalitya described in Ayurveda. Ayurveda treatment provides a holistic approach like Shodhana (purification), Shamana (palliative medicine), Nidana Parivarjana (abstaining from etiology) and Rasayana (Rejuvination). A male patient aged 23 years with complaint of excessive hair fall more than 150 hairs in a day resulting in baldness in forehead, dandruff and Itching all over head was managed by Abhyanga with Dhurdhurpatradi Taila followed by modified bloodletting technique and certain internal Ayurvedic drugs Withinia somnifera, Asparagus recemosus, Glycerhiza glabra Churna 2 gms each and smilax china 1 gm twice a day with water, Kaishor Gugullu 500mg three times a day. 5 Sitting of blood letting once in every week were done.Patient had complete relief in dandruff, itching in scalp, and marked relief in hair fall. The numbers of hair fall daily were less than 20. New hair follicles started to grow in the upper forehead and patient was satisfied and happy with Ayurveda approach.
In-silico study on plant determined flavonoids compounds for the synthetic medications against breast cancer growth
Authors:   Plant Biotechnology Laboratory, Department of Biotechnology, Delhi Technological University, New Delhi-110042, India, Singhal Garima , Roy Arpita ,   Plant Biotechnology Laboratory, Department of Biotechnology, Delhi Technological University, New Delhi-110042, India, Bharadvaja Navneeta ,   Plant Biotechnology Laboratory, Department of Biotechnology, Delhi Technological University, New Delhi-110042, India
Published: February 2022

Breast cancer is one of the genuine wellbeing worries in India bringing about the most elevated death rate in females, which happens because of uncontrolled cell division and can be metastasize to different parts of the human body, and different medications are accessible to its cure. Drugs like Tamoxifen and Herceptin can cure breast cancer however these medications have their unsafe impacts on human body. This study deals with the docking, toxicity, bioactivity and ADME expectation of flavonoids compounds with HER2 and estrogen receptor, to limit the utilization of existing medications. Lipinski's channel is utilized to screen the flavonoids compounds on the premise of five tenets. Out of 200 flavonoids compounds 15 compounds were screened on the premise of Lipinski's channel. The outcomes uncovered that the top positioning screened flavonoids indicates greatest docking and minimum binding energies with the HER2 and ER receptor when contrasted and the accessible medications. The above analysis demonstrated the compounds ST026594 (7-hydroxyflavone), ST070967 (2-(- 4-fluorophenyl)- 4n-chromen-4-one), ST086622 (3-hydroxyflavone) and ST055369 (8-methylflavone) were the best compounds indicating minimum binding energy in correlation with medication Tamoxifen with Estrogen receptor and compounds ST060160 (4-hydroxyflavone) and ST058442 (6,3- dimethylflavone) were the best compounds indicating minimum binding energy in examination with medication Herceptin with HER2 receptor, were likewise bioactive and non dangerous in nature with great pharmokinetics properties and drug likeliness.
Bio-absorption mapping of Caratol-E capsules-The science and brilliance of Siddha system of medicine
Authors:   Research Scientist, Dr.JRK’s Research and Pharmaceuticals Pvt., Ltd., Kundrathur, Chennai, Tamil Nadu-600069, India, Amruthavalli G.V , Rajagopal Gayathri ,   Research Scientist, Dr.JRK’s Research and Pharmaceuticals Pvt., Ltd., Kundrathur, Chennai, Tamil Nadu-600069, India
Published: February 2022

Caratol-e capsules was studied for its effect in altering the stomach ecosystem and found that caratol e capsules does not affect the same. The possible reason for the administration of two capsules in night may be due to its likely effect on melatonin –MSH interaction and this sufficiently explains the importance of caratol e capsules in the treatment of vitiligo and the importance such treatment during night hours as well. Findings of the study discussed in the paper.
Arsenic in the management of leukemia: an Ayurvedic perspective
Authors:   Assistant Professor, B.I.P.S, SPLPIM Campus, Kalyani, Nadia,West Bengal, India, Palbag Satadru , Gautam D.N.S. ,   Associate Professor, Faculty of Ayurveda, BanarasHindu University, Varansai, Uttar Pradesh, India
Published: February 2022

Gauripasan, Harital and Manhasilaare important classical Ayurvedic arsenic containing minerals found in Rasashastra (Indian Alchemy). Though there are no direct references about the role of these minerals in treating leukemia but there are several references of the above minerals in combating blood disorders, infection and anemia which can occur secondary to leukemia. This review discusses the probable role of this arsenic based Ayurvedic compounds in the management of leukemia, its study from ancient classics supporting its therapeutic efficacy and also to draw a comparison among the effectiveness in between several arsenic containing mineral groups in Ayurveda.
The Wiled RET edible plants consumed by the Irula tribals of Walayar valley, Southern Western Ghats of India
Authors:   Department of Botany, Kongunadu Arts and Science College, Coimbatore, Tamil Nadu-641029, India, Venkatachalapathi A , Paulsamy S ,   Department of Botany, Kongunadu Arts and Science College, Coimbatore, Tamil Nadu-641029, India
Published: February 2022

The present study is aimed to know the RET wild edible plants consumed by the Irula tribals of Walayar valley, Southern Western Ghats of India. The study was carried out during 2015 - 2016. A total number of 51 species in 38 genus belongs to 32 families of wild edible plants were enlisted during the survey. The information about each plant the local name of the plant, parts used, mode of use and medicinal uses are documented in separated filed data sheet. Among them 14 plant species are coming under IUCN red listed category. They have a very good knowledge of wild edible plants in their surrounding forest. Plants parts are mostly consumed as direct food. Our study revealed that the Adivasi community in the Walayar Valley continues to have and use the knowledge about the wild edible plants, including their habitat, collection period, sustainable collection, mode of preparation and consumption. To date, this knowledge appears to be fairly well conserved and used as a result of continued reliance of local community on the wild uncultivated foods.
Current perspective on osteoarthritis: a narrative review
Authors: Pokhrel Sony , Nepal Ojashwi
Published: February 2022

Introduction: Osteoarthritis is the most prevalent chronic inflammatory joint disease affecting mobility in humans. It is caused by inflammation, breakdown, and eventual loss of cartilage in the joints. It is one of the ten most disabling diseases in developed countries. In this review we aimed to appraise the current evidence for the short as well as long term prevention and available effective treatment approaches for osteoarthritis. The objective of this study is to discuss about the risk factors, clinical methods of treatment, prevention and recent development in pathophysiological understanding of osteoarthritis.

Materials and methods: Full length published articles and journals were collected from different reliable sites, PubMed, Hinari and Medline. Among the accessed materials, 52 full length articles were selected excluding studies that only provided abstract as published papers.

Results: The incidence and prevalence was high among the people who had suffered from joint injury or undergone joint surgery recently in their lives. The risk was also high in people with bone malalignment, altered shape of bone and muscle strength. High muscle/fat ratio showed a protective effect against KOA prevalence. The incidence also depends on age and sex, obesity, bone density and mass, diet and genetic factors.

Conclusions: The risk is high among people with joint injury, old people, obese, people with poor diet, patients undergone joint surgery and in women after menopause. Definitive treatment for OA hasn’t been available yet but, there are ways for prevention and treatment of OA. Pharmacological treatment includes NSAIDs, non-pharmacological includes exercise, physical activity and diet whereas surgical method includes total joint replacement.
Online teaching learning during COVID-19 pandemic : perception and challenges faced by teachers
Authors: Subba Ramesh , Subba Hem Kumari
Published: February 2022

Introduction: Online teaching can play a vital role in the process of teaching and learning during COVID-19 pandemic. However, teachers’ perceptions and challenges are major factors in the adoption and effectiveness of online teaching learning, especially at institutions where it is newly adopted. This study aimed to investigate the perception and challenges faced by nursing teachers regarding online teaching learning during the pandemic in Bharatpur, Chitwan.

Materials and methods: A web-based cross-sectional survey was undertaken among 162 nursing teachers of different nursing colleges of Chitwan actively involved in online teaching learning for undergraduate and postgraduate programs during the pandemic. Non-probability enumerative sampling technique was used to select the sample. A structured questionnaire consisting of 23 items (5-point Likert scale) covering four domains for teachers perception (usefulness, ease of use, system use and behavioral intention toward online teaching learning) was distributed to the teachers using Google Form from 2021 June 5th to 2021 July 20th. Collected data were analyzed using descriptive and inferential statistics.

Results: More than half (56.2%) of the teachers had good perception towards online teaching learning during COVID 19 pandemic. Teachers faced challenges to implement online teaching learning such as poor internet connection, electricity problem, difficult to assemble all the students for the class, difficult for interaction with students, and lack of information technology skills.

Conclusions: Despite having to confront numerous challenges in the online teaching process, teachers can demonstrate the positive perception toward technology of online teaching. Teachers need to be equipped with e-learning technology for effectiveness of online teaching classes.
Technologies of cleaning and in-line inspection of gas mains
Authors: Banakhevych Yu. V.
Published: February 2022

In-line inspection of pipe metal is an extremely important component of technical diagnostics of gas mains. The main objective of inspection is determining the actual technical condition of gas pipeline and its equipment with subsequent repair of detected defects to ensure reliable operation of the facility. Untimely diagnostics and repair operations lead to higher failure rate and emergencies. Regular diagnostics makes it possible to determine effectively the technical condition and allows establishing the expediency of further operation and recommendations for the elimination of detected defects.
The influence of external and internal factors on stress corrosion cracking of low-alloyed pipe steel
Authors: Nyrkova L. I.
Published: February 2022

The article presents investigation results of the regularities of stress corrosion cracking (SCC) of controllable rolling X70 pipeline steel under the influence of various factors: corrosion-active environment, potential, pre-accumulated stresses, periodic wetting, etc. Factors, acting in the conditions of the gas pipe mains operation, were simulated in the laboratory conditions and their influence on the SCC susceptibility of X70 pipe steel was investigated. It was found that in NS4 solution, potential shifting to the cathode area promotes the increasing of the SCC susceptibility of X70 steel. Under cathodic protection at potential equal to -1.0 V, the fracture characteristics change, a brittle component appears in the fracture, and the coefficient KS increases compared to the breaking of samples without cathodic potential. Under such a potential there may appear some differences in the SCC susceptibility of X70 steel, which have a minor structural features: steel with less contamination of non-metallic inclusions is less susceptible to brittle cracking. Accumulated cyclic stresses, periodic wetting, the presence of coatings with different transient resistance and the stress concentrator promote the increase of the degree of SCC susceptibility of X70 pipeline steel at a potential of -1.0 V.
Debunking Doxastic Transparency
Authors: Sullivan-Bissett Ema
Published: February 2022

In this paper I consider the project of offering an evolutionary debunking explanation for transparency in doxastic deliberation. I examine Nicole Dular and Nikki Fortier’s (2021) attempt at such a project. I suggest that their account faces a dilemma. On the one horn, their explanation of transparency involves casting our mechanisms for belief formation as solely concerned with truth. I argue that this is explanatorily inadequate when we take a wider view of our belief formation practices. I show that Dular and Fortier overstate the extent to which adaptive non-evidentially supported beliefs are rare, and the implausibility of disjunctive evolutionary systems. They should allow a role for the non-truth directed behaviour of our mechanisms of belief formation. On the other hand, we might restrict the explanation offered by Dular and Fortier to the deliberative context, that is, we might understand them as allowing for non-evidential belief formation outside of the deliberative context, but as identifying the key to explaining transparency in the truth-directed evolutionary mechanisms as they operate in the deliberative context. However, this would land them on the second horn of the dilemma: we would then have no different an explanation to one I have offered elsewhere (2018), an explanation which Dular and Fortier explicitly put aside as engaged in a project different from their own. I finish by briefly considering some broader implications relating to explaining transparency, the nature of belief, and the prospects for pragmatism. I conclude that Dular and Fortier’s debunking explanation of transparency bestows an implausible role for truth in fixing our beliefs, or, if it doesn’t, then we simply have the restatement of a view explicitly disavowed by the authors. We are left, then, with an explanation we ought not want, or an explanation we already had
Activities of travel agencies and tour operators in Egypt
Authors: Andrusyak Natalia , Anipko Natalia
Published: February 2022

Egypt is a popular tourist destination for tourists from Ukraine. This destination is the most successful for sale to tourists, as it has the longest duration during the year and is affordable. Despite the fact that the active tourist season in Egypt lasts from March to December, but even in the relatively cold winter months, tourists from Ukraine choose Egypt as a destination. The events of 2020 have significantly affected the activities of both tour operators and travel agencies.
The previously fierce competition has intensified. However, every year there is a decrease in the level of confidence of tourists in tourism enterprises. This is due to the fact that tourists do not always receive reliable information about the tourist product, and often managers do not conduct a full consultation of tourists.
Therefore, it is advisable to study the current state of travel agencies and tour operators, barriers that hinder the development of tourism enterprises and the causes of tourism collapses. This type of research will be relevant in 2021, when new information will be obtained on the functioning of the tourism industry in the Pavid-19 pandemic in 2020. The activity of travel agencies and tour operators of Chernivtsi in the direction of Egypt is analyzed in the work. A survey of travel agencies in Chernivtsi and tourists. Leaders among tour operators of Ukraine for travel agencies in Chernivtsi, leaders among tour operators in Egypt have been identified. The analysis of applications of tourists for selection of tour by tourist agencies of Chernivtsi is carried out, the basic demand for a tourist product of this or that country among the population of the Chernivtsi area is revealed, the countries-leaders on tourist demand are allocated, etc.
Tour operators, which today are leaders in the tourist market of our country, are also leaders in the sale of tourist products to Egypt. Among the leaders are tour operators Join Up, Anex Tour, followed by TPG, Coral, TUI, TEZ Tour. Travel agencies in Chernivtsi today offer holidays in all the famous resorts of Egypt - Sharm el-Sheikh, Hurghada and Marsa Alam. They prefer tourist products, including in Egypt, the two leaders of the tourist market of Ukraine - Join Up and Anex Tour.
The results of a survey of the population of Chernivtsi region and managers of travel agencies in Chernivtsi showed that the leaders in tourist demand are four countries - Bulgaria, Egypt, Turkey and Greece. A total of 856 applications were submitted to travel agencies for processing. Applications for the selection of the tour were analyzed, in the main demand for the tourist product of a country.
Exporting Russian Higher Education in the Conditions of a New Reality
Authors: Nikolaev V. K.
Published: February 2022

The article addresses the mechanism to raise the competitiveness and attractiveness of the Russian higher education in the international educational market through the development of educational services exporting. Currently, the Russian universities have made progress in international students engagement. According to date for 2021, there are 310 thousand of international students studying at Russian universities, which is approximately 8% of the total amount of students. These figures have been achieved due to the large national strategic projects implementation in the sphere of higher education internationalization. In 2021, the Government of the Russian Federation set a new goal to increase the number of international students motivated to study at Russian universities by 50 per cent. In the conditions of the COVID-19 pandemic, achieving the target figures is possible with the use of the modern tools for the university brand promotion in the world educational space.
Russian University Teachers’ Ethical Culture Regulation
Authors: Maksimenko A. A. , Deyneka O. S. , Dukhanina L. N. , Krylova D. V.
Published: February 2022

Based on a review of publications of Russian and foreign researchers, the authors highlight the most significant topics on the deontology of university life. The article presents the results of an analysis of the texts of ethical codes of some leading universities in Russia (National Research University Higher School of Economics, Moscow State University, St. Petersburg State University, Kazan Federal University, Ural Federal University), as well as the results of an online survey (N = 297) of teachers of these universities. The survey was conducted to study the attitude of the teaching staff towards the tools for standardizing the moral culture of universities and the implementation of the values enshrined in the ethical standards of universities and ideals of academic community. Conclusions are made about the ethical attitudes of teachers and the effectiveness of moral regulation, as well as proposals for improving the ethical codes of universities are made.