bluuebunny/crossref_metadata_2025 huggingface dataset:
Proyectos destacados 2021
Authors: Matach Guillermo , Lema Efraín , Carón Ignacio
Published: June 2022

A continuación se recopilan los proyectos más sobresalientes de la asignatura Diseño, durante el período académico de 2021, producidos en la carrera de grado en Arquitectura, de la Facultad de Arquitectura y Urbanismo de la Universidad Católica de Salta, Argentina.Dichos trabajos fueron realizados en los talleres de los arquitectos Guillermo Matach, Efraín Lema e Ignacio Carón, quienes a su vez llevaron a cabo el proceso de selección de los reconocidos.Los proyectos consisten en configuraciones arquitectónicas de mediana y gran escala, que contemplan en su interior usos mixtos vinculados tanto al comercio, la economía del conocimiento, la cultura y el habitar colectivo. En todos los casos, el sitio de implantación es en sectores o manzanas ubicadas en áreas consolidades de la capital salteña.
Técnica decisória e diálogo institucional: decidir menos para deliberar melhor
Authors: Marinoni Luiz Guilherme
Published: June 2022

O texto analisa a técnica decisória constitucional com o fim de reforçar o diálogo institucional. Mediante o emprego do método histórico-comparado, busca-se demonstrar que, quando a Corte percebe a necessidade de aguardar o resultado da deliberação popular e parlamentar, lhe é legítimo decidir sem aprofundar a discussão teórica sobre a questão carente de deliberação. A fundamentação se vale de importantes posições doutrinárias e de relevantes decisões da Corte do Segundo Circuito e da Suprema Corte dos Estados Unidos, considerando-se especificamente a técnica do second look e o minimalismo, de Cass Sunstein. O objetivo é demonstrar que a Corte, sem inibir a deliberação que lhe é imprescindível para decidir questão de maior amplitude, tem meios para decidir pela (in)constitucionalidade, tutelando os direitos durante o tempo do diálogo constitucional.
O combate à Covid-19 e o papel do Supremo Tribunal Federal: entre direito à saúde e conflitos federativos
Authors: Sarlet Ingo Wolfgang , Barbosa Jeferson Ferreira
Published: June 2022

O objetivo do artigo é identificar e analisar os principais temas em discussão no Supremo Tribunal Federal (STF) relativamente ao direito à saúde e ao combate à Covid-19. As decisões pesquisadas foram selecionadas por meio dos informativos de jurisprudência do STF, abarcando o período de março de 2020 até dezembro de 2021. Fontes de informações também foram a obra Case Law Compilation Covid-19 e o Painel de ações Covid-19, ambos de autoria do STF, divulgados nos informativos. A síntese das discussões revela que o contexto federativo perpassa os temas de conflito. Também há um reforço da dimensão transindividual do direito à saúde, sem prejuízo da individual. Existe um esforço por assegurar tanto a prerrogativa da União de estabelecer critérios gerais e exercer a coordenação geral no que diz com as políticas e medidas em geral de combate à pandemia, quanto por garantir que estados e municípios não fiquem imobilizados. A maior deferência a critérios científicos, evidências e estatísticas aparece como uma tendência. Também há um incremento de ações do tipo estruturante, indicando um caminho viável para o diálogo institucional e para o equilíbrio entre os poderes. Por último, evidencia-se uma tendência de fortalecimento da proteção de grupos vulneráveis.
O direito à participação dos povos originários e o STF
Authors: Bahia Alexandre Gustavo Melo Franco de Moraes , Bacha e Silva Diogo
Published: June 2022

O texto discute como o Supremo Tribunal Federal aplica a Convenção n. 169 da Organização Internacional do Trabalho – OIT quanto à necessidade de consulta e participação dos povos originários e tradicionais na tomada de decisões por parte do Estado brasileiro. Argumenta-se que o Supremo Tribunal Federal não tem tido uma única orientação quando decide tais casos, ora conferindo efetividade à Convenção Internacional, ora entendendo que a consulta seria ato meramente protocolar e não vinculativo. Procura mostrar a melhor interpretação da exigência de consulta prévia e argumenta que sua compreensão a partir da Constituição de 1988 e da Convenção n. 169 é proteger e dar voz aos povos originários e comunidades tradicionais e que nenhum argumento pode, a priori, se sobrepor àqueles que serão diretamente afetados. O texto se vale de metodologia reconstrutiva e de técnicas de pesquisas documentais, doutrina e jurisprudência, nacional e da Corte Interamericana de Direitos Humanos e tem como marcos teóricos teorias de(s)coloniais em um diálogo com a teoria discursiva de Habermas.
CHARLILI (MENCHARGE LILIN LITERASI) SAAT PANDEMI BERBUAH BUKU ANTOLOGI
Authors: Sumarno Wahyuni Budi Hastuti
Published: June 2022

Abstract
This study aims to describe literacy development strategies through writing culture to produce an anthology of short stories. The movement to write books with students is an effort to motivate students to write about their learning experiences during the pandemic. With the activity of writing books for students at MTs Negeri 34 Jakarta, it is hoped that it can increase the literacy movement of madrasa residents. The methodology used in this paper is descriptive qualitative by describing the mentoring activities in the project of making an anthology book. The activity of writing an anthology book with students is carried out in several stages, namely (1) the implementation stage in the form of providing understanding, motivation; (2) the implementation stage, students join the WhatsApp group, providing signs for writing distance learning experiences; (3) the completion stage in the form of activities sending manuscripts, editing manuscripts by each student, sending manuscripts to publishers, editing manuscripts sent from publishers, printing processes, promotions and responses from students after receiving their books. Writing books can give students flexibility in exploring their experiences, developing vocabulary, providing strengthening character education. So that the final result to be achieved is a project-based learning product, namely an anthology of short stories with an ISBN.
 
Abstrak
Penelitian ini bertujuan untuk menggambarkan stategi pengembangan literasi melalui budaya menulis untuk menghasilkan buku antologi cerpen. Gerakan menulis buku bersama siswa ini sebagai upaya untuk memotivasi siswa untuk menulis tentang pengalaman belajar selama pandemi. Dengan adanya kegiatan menulis buku, siswa di MTs Negeri 34 Jakarta diharapkan dapat meningkatkan gerakan literasi warga madrasah. Metodologi yang digunakan pada penulisan ini adalah deskriptif kualitatif dengan menggambarkan kegiatan  pendampingan pada proyek membuat buku antologi. Kegiatan menulis buku antologi bersama siswa dilakukan melalui beberapa tahap, yaitu: (1) tahap pelaksanaan berupa kegiatan pemberian pemahaman, motivasi; (2) tahap pelaksanaan, siswa bergabung dalam  grup WhatsApp, pemberian rambu-rambu penulisan pengalaman pembelajaran jarak jauh; (3) tahap penyelesaian berupa kegiatan pengiriman naskah, edit naskah oleh masing-masing siswa, pengiriman naskah ke penerbit, edit naskah yang dikirim dari penerbit, proses cetak, promosi dan tanggapan dari siswa setelah menerima buku hasil karya mereka. Menulis buku dapat memberikan keleluasan siswa dalam mengeksplor pengalamannya, mengembangkan perbendaraan kata, memberikan penguatan pendidikan karakter. Sehingga hasil akhir yang dicapai adalah sebuah produk pembelajaran berbasis proyek yaitu sebuat buku antologi cerpen ber-ISBN.
Implementation of Digital Technologies in the Institution of Customs Payments
Authors: Skiba Vladimir Y. , Bykov Andrey M.
Published: June 2022

The article is devoted to an important and urgent problem of introducing digital technologies into the institute of customs payments, which are designed to provide automatic verification of the correctness of calculation and automatic control of the completeness of customs payments, accounting and timeliness of their transfer to the federal budget, as well as to create conditions for simplifying the interaction of participants in foreign economic activity with customs authorities, reduce the administrative burden on business. The conditions for the introduction of digital technologies into the institute of customs payments are analyzed, technologies for solving problems of automatic verification of the correctness of accrual, control of completeness, timeliness of payment and accounting of customs payments are considered, and the technology of information interaction of participants in foreign economic activity (declarants) with customs authorities when performing customs operations related to the payment and accounting of customs payments is also given.
The Effect of Human Resource Skills and Capabilities on SMEs Performance
Authors: Wijaya Reni , Yadewani DORRIS , Kurniati Karim
Published: June 2022

This study aims to investigate more deeply the impact of skills and abilities on the performance of Small and Medium Enterprises in Kota Pariaman. The population of this research is 4,281 Small and Medium Enterprises located in Pariaman City where the number of samples is 98 SMEs. The technique used in collecting data for this research is to use Field Research, then the technical data analysis used is factor analysis. Hypothesis testing is carried out using Statistical Program Social Scence (SPSS) 24.0 for Windows by using factor analysis, among others instrument test, classical assumption test, Goodness of Fit test, multiple linear regression analysis. The results of this study indicate that a) There is a positive influence of skills on the performance of small and medium enterprises of 13.2%. b) There is a positive effect of ability on the performance of small and medium enterprises of 30.8%. c) There is a positive influence of skills and abilities on the performance of small and medium enterprises of 34.1%.
Menelisik Problematika dan Strategi Pelaksanaan Misi Dalam Konteks Indonesia
Authors: Bombongan Rantesalu Marsi
Published: June 2022

The purpose of this research is to identify the challenges faced in the implementation of missions in Indonesia and the appropriate strategies used in the implementation of missions. The method used is descriptive qualitative with reference sources from books and the latest studies on missions through journals. The results showed that the implementation of missions in Indonesia experienced many challenges such as a very strong cultural problem in the lives of recipients, very diverse language problems and responses from adherents of other religions who had negative views on the implementation of Christian missions. In order to keep the mission going, it needs the right strategy and continue to take advantage of every opportunity available and maximize the available facilities.

Tujuan dari penelitian ini adalah untuk mengidentifikasi tantangan-tantangan yang dihadapi dalam rangka pelaksanaan misi di Indonesia dan strategi yang tepat digunakan dalam pelaksanaan misi. Metode yang digunakan adalah deskriptif kualitatif dengan sumber referensi dari buku-buku dan kajian terbaru tentang misi melalui jurnal. Hasil penelitian menunjukkan bahwa pelaksanaan misi di Indonesia memiliki banyak tantangan seperti persoalan budaya yang sangat kuat dalam kehidupan penerima, persoalan bahasa yang sangat beragam dan respon dari pemeluk agama lain yang memiliki pandangan negatif terhadap pelaksanaan misi Kristen.  Agar misi tetap berjalan maka dibutuhkan strategi yang tepat dan terus memanfaatkan setiap peluang yang ada dan memaksimalkan fasilitas yang tersedia.
Medicinal plants of Acharya Nagarjuna University campus and its immediate surrounding environment
Authors: Babu K. , Ammani K.
Published: June 2022

A study of medicinal plants was carried out in Acharya Nagarjuna University and its surrounding environment. Altogether 153 species belonging to 64 families were identified and their uses have been described giving their vernacular name, Telugu (Local name). The Family and Botanical name of species followed by local name and their uses have been provided in the paper.
A supplement to the flora of Lahaul-Spiti
Authors: Sekar K. , Srivastava S.
Published: June 2022

The paper deals with 115 taxa of Angiosperms belonging to 24 families, 76 generas, as supplement to the Flora of Lahaul-Spiti, Himachal Pradesh.
Selaginella Chrysocaulos (Hook. ET Grev.) Spring – An addition to the pteridophytic flora of central India
Authors: Sikarwar R. , Pande H.
Published: June 2022

Chitrakoot hill is most sacred and legendry hill for Hindu pilgrimages. It is situated on the border of Satna district of Madhya Pradesh. Selaginella chrysocaulos was collected from Satna District and is being reported for the first time from Central India. A complete description with illustration is provided.
Efficiency of Using Geoinformation Systems in the Design of Gas Distribution and Gas Consumption Networks
Authors: Bespalov Vadim Igor , Stakyan Mihran Grigor , Grishin Grigorii Sergey
Published: June 2022

The scientific article is devoted to determining the effectiveness of the use of geoinformation systems (GIS) in the design of gas distribution and gas consumption networks. An experiment was carried out on a laboratory stand modeling ring, dead-end and mixed gas networks. The electronic model of a gas network identical to the laboratory stand in the ZuluGaz 10.0 software package, a module for expanding the GIS functionality for calculating gas supply networks designed to solve various industry. A comparative analysis of the results of an experiment and the results obtained during simulation in GIS is carried out. Based on the analysis, a conclusion is made about the accuracy of the GIS results and the feasibility of using GIS for the design of gas distribution and gas consumption systems.
Method of Calculation of the Sediment Drying Structure in Natural Conditions
Authors: Butko Denis Alexander , Sarukhanyan Arestak Aramayis
Published: June 2022

Dewatering of sediments of natural water treatment plants is one of the most important technological and environmental problems of their operation. The use of drying in natural conditions ensures low energy consumption with the achievement of the necessary results in the moisture content of the sediment. The increase in the rate of dehydration is facilitated by the use of structures using the capillary effect to increase the rate of dehydration. The designs of dewatering sites with such elements have been developed and the article presents the method of their calculation.
Automated Real Estate Valuation With Machine Learning: A Case Study on Apartment Sales in Yerevan
Authors: Sergoyan Henrik Tigran , Bezirganyan Grigor Vahan
Published: June 2022

Real estate is one of the major sectors of the Armenian economy and has been developing dynamically since Armenia transitions from planned to market economies in early 1990s. More recently, large online platforms have been developed in Armenia to advertise real estate offerings, thus reducing information asymmetry, and increasing liquidity in both sales and rental markets. Simultaneously, granular geospatial data became increasingly affordable via platforms such as OpenStreetMap, Google Maps and Yandex Maps. With granular data concerning a representative portion of the real estate offering available online, it is increasingly tenable to monitor the real estate market in real time and develop analytical tools that can automatically and accurately estimate the value of real estate assets based on their internal and external features. This paper sets out to analyze Armenia real estate market and assess the performance of a special class of machine learning models while predicting the price of a square meter of apartments in Yerevan. Furthermore, it is presented the way to determine the most decisive factors which have an influence on the price of apartments on sale.
Effectiveness of Istiku in Teaching Mtb-Mle 1 to the Pupils of Mmsu-Les
Authors: Lagura Romelyn , Decano Jan Jan , Lorenzo Natividad , Diza Marie Joyce
Published: June 2022

This study aimed to understand the effectiveness of the use of puppets in teaching Mother Tongue-Based Multilingual Education (MTB-MLE 1) to the pupils of Mariano Marcos State University- Laboratory Elementary School (MMSU-LES), by studying its usefulness in the familiarization of words. It examined how well the pupils recognize Iluko words and their meaning through performing the model. It analyzed the meaning conveyed and the words which are presented by the movement and acting of the puppet and actors throughout the performance. This study employed the experimental research design to examine the work of The Puppeteer (Teacher) within the context of the teaching and learning process. The challenge was to analyze The Puppeteer’s performances using the product-oriented method which is a contributory factor in opening the minds of the learners in grasping different Iluko words in the dialogues during the whole puppet presentation. Product oriented analysis deals with the performance as a finished aesthetic product.With this study, the researcher was able to execute the model to the target clienteles during their MTB-MLE 1 classes. As a result, the model gained a positive evaluation from the cooperating school and agreed its usefulness in teaching the subject. In addition, the respondents assessed the product for recommendation. On the part of the learners, they were able to distinguish different Iluko words and differentiate it from parts of speech whether they were used as an article, noun, verb, and adjective and simple adverb, preposition and conjunction. As part of the assessment, they were capable to use several Iluko words in their own sentences. This implied that the use of ISTIKU Model was effective in teaching MTB-MLE to the grade one pupils.
Ficus vogelii methanol leaf extract ameliorates inflammation and arthritis by modulating osmotic fragility in C57BL/6J mice
Authors: Nwaehujor Chinaka
Published: June 2022

The study evaluated the membrane-stabilizing potentials in red blood cells and anti-inflammatory properties in C57BL/6J mice of the methanol leaf extract of Ficus vogelii. Animals were treated orally with different doses of the extract (50, 100, 200 mg/kg) for 30 days and their blood was measured for membrane stability at different saline concentrations. Diclofenac (12.5 mg/kg) or Indomethacin (10 mg/kg) was used as standard in the anti-inflammatory studies. The mean corpuscular fragility (MCF) values and their corresponding percentage stabilization increased significantly (p≤0.05) in the treatment groups compared to the negative control. Treatment of mice with 50, 100 and 200 mg/kg of the extract significantly (p≤0.05) inhibited carrageenan-induced paw oedema in mice. The highest dose (200 mg/kg) showed lower anti-inflammatory activity compared to Diclofenac (12.5 mg/kg). Daily administration of the extract significantly (p≤0.05) suppressed adjuvant-induced paw arthritis by day 15 and 30 post arthritis induction. Ficus vogelii extract inhibited granuloma formation significantly. The anti-inflammatory effects of methanol leaf extract of Ficus vogelii on granuloma formation were comparable to that of Indomethacin (10 mg/kg). In summary, this study showed that the methanol leaf extract of Ficus vogelii possessed membrane-stabilizing potentials and anti-inflammatory properties, therefore, providing further proof that the leaves contain an active compound with potent anti-inflammatory activity
Hippocampal Astrogliotic Reduction in Scopolamine Hydrobromide-Induced Alzheimer’s Type Cognitive Dysfunction Wistar Rats Following Administration of Aqueous Extract of Telfairia Occidentalis (pumpkin) seeds.
Authors: Mba Eru
Published: June 2022

Astrocytes are small star-shaped glial cells that maintain normal human brain physiology including secretion of several active compounds and the formation of blood brain barrier. Reactive astrocytes support regenerating axons and also, actuate some genes responsible for the induction of synapse formation. In this study, the effect of aqueous extract of Telfairia occidentalis seeds on hippocampal astrogliosis was probed using scopolamine-induced Alzheimer’s type cognitive dysfunction Wistar rats. Thirty Wistar rats weighed between 180-200g were randomly grouped into five designated A, B, C, D and E.  Each group contained six rats. Alzheimer’s type cognitive dysfunction was induced in groups B to E by administering intraperitoneally, 1 mg/kg body weight of scopolamine for seven days before Donepezil and the aqueous extract of Telfairia occidentalis seeds for fourteen days. Twenty-four hours after the last administration, the animals were sacrificed; their brain tissues perfused and stained with glial fibrillary acidic protein (GFAP) dye. Results revealed prominently stained astrocytes with their processes intact (group A). Some densely stained numerous astrogliosis with hypertrophied fibres were noticed in group B. Group C demonstrated prominent astrocytes with hypertrophied fibres, group D, moderately stained astrogliosis with hypertrophied fibres while group E showed numerous astrocytes with prominent nuclei and hypertrophied fibres. In conclusion, there was reduced hippocampal astrogliosis mostly in group D treated with Telfairia occidentalis which may neutralize oxidative stress and enhanced learning and memory in the Wistar rats of the present study.
Carpolobia lutea Root Extract Improved Steroidogenic Activity in Male Wistar Rats Exposed to Cadmium
Authors: Akinola Adeniran Oluwadamilare , Wahab Oyeyemi Adekunle , Raji Yinusa
Published: June 2022

Cadmium (Cd) is known to affect reproductive functions adversely. Carpolobia lutea is a protective herbal derivative due to its antioxidant potential. This study investigates the steroidogenic activities of methanol extract of Carpolobia lutea root on cadmium-induced reproductive toxicity in male Wistar rats. Carpolobia lutea root was obtained in Ijare via Akure. The plant was authenticated at the herbarium of Forestry Research Institute of Nigeria (FRIN), Ibadan, Nigeria, with FHI number 109784. The methanol extract Carpolobia lutea root (MCL) was obtained by Soxhlet extraction. Thirty male Wistar rats (150-170g) were used in this study (n=5) and treated as follows: Control, Cd (2 mg/kg), Cd+MCL (2 mg/kg+100 mg/kg), Cd+MCL (2 mg/kg+200 mg/kg), MCL (100 mg/kg), and MCL (200 mg/kg). The extract was administered orally for eight weeks, and a single dose of 2 mg/kg Cd was given intraperitoneally. Serum Follicle Stimulating Hormone (FSH), Luteinizing hormone (LH), testosterone levels, testicular hydroxysteroid dehydrogenases (HSDs) activities and Steroidogenic Acute Regulatory protein (StAR) expression were evaluated. Data were subjected to descriptive statistics and analysed using ANOVA at p<0.05. Serum FSH, LH, testosterone levels, 3β-HSD, 17β-HSD activities and StAR expression were significantly reduced (p<0.05) in Cd group. The co-administration of Cd with MCL (200mg/kg) significantly increased (p<0.05) serum FSH, LH, testosterone levels, 3β-HSD, 17β-HSD activities and StAR expression when compared with Cd group. Carpolobia lutea root extract improved steroidogenic activity in male Wistar rats exposed to cadmium.
Ethanolic extract of Salacia nitida root bark ameliorates lipid peroxidation and hepatosplenomegaly in Plasmodium berghei–malaria infected mice
Authors: Nwiloh Barine , Uwakwe Augustine Amadikwa , Akaninwor Joyce Oronne
Published: June 2022

The root bark of Salacia nitida L.benth (celastraceae) is used as remedy for malaria and typhoid fever in Southern part of Nigeria. This study is designed to evaluate the effect of treatment with ethanolic extract from root bark of S. nitida on lipid peroxidation, hepatomegaly and splenomegaly in Plasmodium berghei-malaria infected mice. Thirty malaria-infected and six uninfected mice were used for the study. 280, 430, and 580 mg kg-1 body weight day-1 of ethanolic extract and 4 mg kg-1 body weight day-1 of artesunate were administered orally to infected mice in groups B, C, D, and E, while 4 ml kg-1 body weight day-1 of physiological saline was given to infected untreated mice in group A and the uninfected untreated mice in group F. Treatments were done for five days. Levels of malondialdehyde were measured as means of assessing lipid peroxidation in the experimental animals. Weights of experimental animals, liver, and spleen, and the length of spleen from experimental animals were also measured. Animal’s liver and spleen-body weight ratios were determined. Results from the study showed significant decrease (P < 0.05) in levels of malondialdehyde, and significant increase (P < 0.05) in body weights. Also, significant decreases (P < 0.05) were seen in the weights of liver and spleen, lengths of spleen, and organ-body weight ratios of malaria-infected treated mice. Therefore, this study confirmed that ethanolic extract from root bark of S. nitida is effective in the treatment of malaria, as it is seen in its ability to attenuate lipid peroxidation and hepatosplenomegaly in mice, thus corroborating its traditional use for the treatment of malaria.
The hypotensive effect of the aqueous calyx extract of Hibiscus sabdariffa may occur through the attenuation of Autonomic nervous system activity
Authors: Mojiminiyi Frank , Aliyu Buhari , Oyeniran Oluwatosin , Isu Alex
Published: June 2022

This study tested the hypothesis that the hypotensive effect of the aqueous calyx extract of Hibiscus sabdariffa (HS) occurs through autonomic mechanisms that may be associated with a reduction in the double product (DP) of the heart. Experiments were performed in accordance with the Principles of the Declaration of Helsinki. Following ethical approval and informed consent, the Harvard step test (HST) was performed in healthy subjects (n=14) to activate the autonomic nervous system before and after the oral administration of 15mg/kg HS. The blood pressure (BP) and heart rate (HR) responses were measured and DPs and the mean arterial pressure (MAP) were calculated. Results were expressed as mean ±SEM. Paired t-test and one way ANOVA with a posthoc Bonferoni test were used for statistical analyses. P<0.05 was considered significant. HST without HS resulted in a significant rise in MAP, HR and DP (112.6±2.7mmHg, 97.7±2.5/min and 12630.0±642 mmHg.bpm) from the basal values (98.5±2.3mmHg, 76.5±2.0/min and 8730.7±354.9 mmHg.bpm, P<0.001, P<0.01 and P<0.001 respectively). In the presence of HS, HST-induced changes (∆MAP=7.8±1.6mmHg; ∆HR=8.1±1.6/min; ∆DP= 1113.6±103.4 mmHg.bpm) were significantly dampened compared to its absence (∆MAP= 13.3±2.6mmHg; ∆HR=17.0±3.7/min; ∆DP= 3899.3±287.2 mmHg.bpm; P<0.001, P<0.01 and P<0.0001 respectively). The HST-induced increase in BP, HR and DP suggest sympathetic nervous system (SNS) activation and parasympathetic nervous system (PNS) withdrawal associated with an increased cardiac O2 consumption and workload. These were dampened by HS suggesting that its hypotensive effect occurs through the inhibition of SNS activation, PNS withdrawal and an associated reduction in cardiac O2 demand and workload.
Discourse clitics in the texts of 12th–16th century Russian chronicles
Authors: Györfi Beáta
Published: June 2022

The present research is aiming at the investigation of the distributional, syntactic and paradimatic features of Old Russian (OR) discourse clitics. Clitics constitute a special class in OR, as despite the relative free word order, their position is fixed in the clause. From the three types of OR enclitics (discourse, pronominal and auxiliary) the least attention has been paid to discourse clitics. An investigation of their frequency, distributional properties and role in the information structure of OR clauses by corpus linguistic methods could provide new perspectives for the research of OR word order as well.
Impact of the Changes in the Administrative and Territorial Structure of the Ottoman Empire on the Development of Cities in the Bulgarian Lands During the 19th Century (Until 1878)
Authors: Muchinov Ventsislav
Published: June 2022

During the 19th century, significant changes occurred in the administrative and territorial structure of the Balkan provinces of the Ottoman Empire. The article analyzes the impact that these changes have had on the development of cities in the Bulgarian lands under Ottoman rule. The administrative rise of cities, such as Plovdiv, Bitola, and Ruschuk (Ruse), stimulated their economic and demographic development instead of other urban centres that were important in the past, such as Sofia, Nikopol, and Silistra. At the local level, the changes in the Ottoman administrative system have also had a significant impact, contributing to the upward development of settlements proclaimed as cities in the Stara Planina, Sredna Gora, and Sub-Balkan regions, such as Gabrovo, Koprivshtitsa, Panagyurishte, etc.
Drinago – Belgrade in Medieval Portolan Maps
Authors: Voynikov Zhivko
Published: June 2022

The strange name of the city of Drinago first appeared on Angelino Dalorto’s “portolan” map from 1325. In later “portolans” made by other cartographers, the name continues to be used. In terms of its geographical location, the city of Drinago in question corresponds to Belgrade. The name Drinago itself is a distorted variant of the Latin-Hungarian name of the city “Alba de Nander” > “Denader” > “Drinago”. It is especially interesting that Dalorto placed above the city an image of a flag with the monogram “Ш” of the ruling Bulgarian dynasty of the Shishmanids. This shows that, around 1325 when the map was drawn, Belgrade was under the rule of Tsar Michael Shishman. This is indirectly confirmed by a letter of Pope John XXII from 1329 to the Bishop of Belgrade, in which he mentions that the city is under the rule of the Bulgarian Empire. Thus, the information on the map is confirmed by the Pope’s letter.
Assessment of Aflatoxins production and its various Control strategies: A Review
Authors: Hassan Syeda Mona , Afzal Nosheen
Published: June 2022

Mycotoxins specifically the aflatoxins contaminate about 25% of the agricultural products in the world. They effect greatly the growth rate, feed intake, and feed conversion ratio. There is a great economical loss to farmers due to loss of food values and effecting human as well as animal health. The different preventive measures are in use to control fungal contamination such as chemicals (acids, bases, and salts), HSCAS ,zeolite polymers, activated charcoal and yeast with variable findings. Fraction of yeast sludge has proved to minimize the adverse effects of aflatoxicosis due to the presence of manno-oligosaccharides in its cell wall. The present review highlights the remedial measures particularly yeast sludge to control aflatoxicosis.
Proteolysis-targeting Chimeras Technology for Selective Protein Degradation
Authors:   State Key Laboratory of Biopolysaccharide Fiber Forming and Ecological Textile, Xia Yeqing
Published: June 2022

Proteolysis-targeting chimeras technology has emerged as a new therapeutic strategy that take advantage of endogenous ubiquitin-proteasome system (UPS) to selectively degrade oncoproteins. It has been developed from peptide-based PROTACs to small molecule-based ones, with capability to degrade a variety of target proteins with unprecedented advantages compared with traditional inhibitors. PROTACs have attracted the interest of both academia and industry and developed rapidly in the past decades. To date, there has been approximately 13 drugs already entered the clinic. However, as a new technology, it is facing many problems and challenges as well. This review will begin with introduction of common structure and rational design of PROTACs, with concentration on their significant features compared with traditional inhibitors. Then, different types of PROTACs will be discussed, followed by brief description of PRATACs that have reached the clinical stage.
Effect of citalopram combined with psychological intervention on cellular immunity and negative emotion in patients with primary liver cancer
Authors:   the Fourth People’s Hospital of Zibo, Wang Suling
Published: June 2022

To explore the effect of citalopram combined with psychological intervention on cellular immune function and negative emotion in patients with primary liver cancer. 124 patients with primary liver cancer from June 2018 to August 2019 were selected. 62 in the observation and 62 in the control. In the control received routine interventional therapy for liver cancer, while in the observation were treated with citalopram combined with psychological intervention. Before and after treatment, CD3+, CD4+, CD4+/CD8+, NK cells and other cellular immune indexes were compared; core quality of life scale scores of cancer patients before and after treatment were compared; MMSE, HAMD and HAMA scores. The levels of CD3+, CD4+, CD4+/CD8+ and NK cells in the observation were higher than in the control after treatment. After treatment, MMSE 83.17 ± 4.47, HAMD 67.51 ± 7.71 and HAMA 60.42 ± 5.83 in the observation group were higher than those in the control group. Citalopram combined with psychological intervention in the treatment of patients with primary liver cancer is conducive to the protection of cellular immune function, and has positive significance in regulating patients’ mood, improving patients’ psychology and improving patients’ quality of life.
Opportunities for the Development of Cognitive Functions in Preschool Children Through Emotions
Authors:   Katolícka univerzita v Ružomberku, Pedagogická fakulta, Inštitút Juraja Páleša v Levoči, Katedra špeciálnej pedagogiky a liečebnej pedagogiky, Kolibová Daniela , Dolinská Eva ,   Katolícka univerzita v Ružomberku, Pedagogická fakulta, Inštitút Juraja Páleša v Levoči, Katedra predškolskej a elementárnej pedagogiky sociálne znevýhodnených skupín
Published: June 2022

Educational practice currently deals with the emotions of preschool children to a small extent, so we are of the opinion that their preparation is not sufficient for the school and for life, too. We came to this knowledge when we were working with preschool children hospitalized in hospital. The aim of the presented study is to analyse the opportunities of developing cognitive functions of preschool children through working with their emotions. The goal was set because of that in the practice is not the sufficient account of an association of the child’s cognitive and emotional development. We approached this goal through qualitative and quantitative research, in which the level of partial cognitive functions of children before and after working with their emotions were diagnosed. To diagnose children from the research group, we used the B. Sindelar method and the B. Bays method “PATH”. In the practical part we present the goal of the research - the importance of the relationship between cognitive functions and emotions. The sub-targets are formulated in research questions and hypotheses about differences in children's performance, which were statistically verified. Based on the survey, a discussion and conclusions for practice are formulated.
Art Talents in the Context of a Specific Research Focus
Authors:   Paneurópska vysoká škola, Fakulta masmédií, Ústav dizajnu médií, Benčič Stanislav , Kováčová Barbora ,   Katolícka univerzita v Ružomberku, Pedagogická fakulta, Katedra pedagogiky a špeciálnej pedagogiky, Valachová Daniela ,   Univerzita Komenského v Bratislave, Pedagogická fakulta, Hudecová Anna ,   Katolícka univerzita v Ružomberku, Pedagogická fakulta, Katedra pedagogiky a špeciálnej pedagogiky
Published: June 2022

The scientific study presents a survey of the outcomes and research results obtained through a research tool by a questionnaire from the teachers of the basic art schools in Slovakia. Interpretation of research data in the form of categories - characters and determinants of artistic talent and talent of children and pupils has a representative function. Results of the mentioned group of respondents will be further compared with groups of teachers to different levels of schools.
SOSYO-DİJİTAL EŞİTSİZLİK EKOSİSTEMİNDE SANAL GERÇEKLİKTEN METAVERSE’E ERİŞİLEBİLİRLİK: İÇERİDEKİLER VE DIŞARIDAKİLER
Authors: ERKEN Fatih
Published: June 2022

Dünyada derinleşerek sürmekte olan sosyo-dijital eşitsizlikler, sanal gerçeklik ve Metaverse teknolojileri ölçeğinde, görme engelli bireyleri kapsayacak şekilde genişlemektedir. Konunun güncel durumunun değerlendirildiği bu makalede; dezavantajların kesişimine, sosyo-dijital eşitsizliğe, sanal gerçeklik ve Metaverse’e erişilebilirliğe ilişkin problemler, mevcut çalışmalara değinilerek ortaya konulmaktadır. Bu çerçevede, meta evrenin sosyo-dijital eşitsizlik potansiyeli tartışılarak soruna ilişkin çözüm önerileri sunulmuştur. Çalışma; Metaverse’ün görme engelliler açısından yaratacağı dezavantajların, sosyo-dijital eşitsizlikler çerçevesinde anlaşılması, bilinmesi ve vurgulanması açısından önem taşımaktadır.
A Rare Focal Inflammatory Process After a Pufferfish Bite
Authors: ACE Gülseren , ACE Zekeriya Buğrahan , BATUR Ali , ERBİL Bülent
Published: June 2022

Aim: Attacks and bites of marine animals are very rare in Turkey. The highly venomous pufferfish (Lagocephalus sceleratus), which often causes systemic toxicity with its toxin (tetradotoxin), could also cause focal toxicity due to bites.

Case: A 57-year-old healthy female patient was admitted to the ED with the complaints of inflammation and wounds on the anterior aspect of the leg after a fish bite. 15 days before the admission, complaints of inflammation and pain occurred because of a pufferfish bite in the sea near the shore. In this case, we aimed to present the clinical changes detected after the 6-week follow-up of the patient who presented to the emergency department (ED) after a pufferfish bite that showed a local course.

Conclusion: The tetradotoxin (TTX), which is especially found in the liver and reproductive organs of puffer fish. acts through sodium channels. There is no treatment or antitoxin available for enteral systemic poisoning. Symptomatic supportive treatment is recommended. In this patient who did not have any chronic disease, the healing process took over 2 months after puffer fish bite. In countries with a coast to the sea such as Turkey, it is necessary to be careful about the clinical situations that may occur after contact with sea creatures. Global warming and illegal hunting, can cause sea creatures to reproduce and live, in unusual habitats. This leads to unconventional and unknown medical conditions after wilderness contacts.
Acreditación de la existencia de pareja de hecho en orden a devengar la pensión de viudedad en el régimen de clases pasivas: la jurisprudencia contenciosa se reencuentra con la social.
Authors: Cavas Martínez Faustino
Published: June 2022

Desmarcándose de la solución adoptada en su sentencia de 7 de abril de 2021 (recurso de casación 2479/2019), en la STS-CA 372/2022, de 24 de marzo, la Sala Tercera del TS recupera su doctrina general -coincidente con la mantenida por la Sala Cuarta- asertiva de que la prueba de la existencia de una pareja de hecho solamente puede acreditarse, a los efectos del reconocimiento del derecho a la pensión de viudedad, mediante los medios expresamente señalados en el art. 38.4 del Real Decreto Legislativo 670/1987, por el que se aprueba el texto refundido de la Ley de Clases Pasivas del Estado, es decir, mediante la inscripción en un registro específico autonómico o municipal del lugar de residencia o mediante documento público, formalización de la pareja de hecho que debe ser anterior, al menos, en dos años al fallecimiento del causante. Reitera doctrina de la sentencia de 28 de mayo de 2020 (recurso de casación 6304/2017) y aclara que la diferente solución que aplica la STS-CA 480/2021, de 7 de abril, responde a las circunstancias concurrentes en el caso concreto.

Distancing from the solution adopted in its judgment of April 7, 2021 (appeal number 2479/2019), in STS-CA 372/2022, of March 24, the Third Chamber of the Spanish Supreme Court recovers its general doctrine wich states that the existence of a unmarried partner, in order to obtain the widow's pension, can only be proved by the means expressly indicated in article 38.4 of Royal Legislative Decree 670/1987, which approves the revised text of the Law on Passive Classes of the State: registration in a specific regional or municipal registry of the place of residence or by public document, formalization of the non marital couple that must be earlier, at least two years after the death of the deceased. The Supreme Court confirms the doctrine of the judgment of May 28, 2020, and clarifies that the different solution applied by STS-CA 480/2021, of April 7, responds to the concurrent circumstances in the specific case.
Concurrencia desleal y procedencia del despido disciplinario
Authors: García Romero Belén
Published: June 2022

Despido disciplinario procedente por concurrencia desleal. Conducta de intervención y apoyo en las actividades de captación de patrocinadores e intermediación de publicidad para empresa creada por su superior jerárquico en el mismo campo y sector que la demandada, con utilización de medios de su empleadora y durante el tiempo de trabajo. Voto particular.

Fair disciplinary dismissal for unfair competition. Conduct of intervention and support in the activities of attracting sponsors and intermediation of advertising for a company set up by his hierarchical superior in the same field and sector as the defendant, with the use of his employer's resources and during working time. Individual opinion.
El pacto a través del que se obliga a los pilotos contratados a devolver el coste del curso de habilitación que ha sido impartido por la misma empleadora es lícito, aunque enmascare un pacto de permanencia impropio
Authors: Ballester Pastor Inmaculada
Published: June 2022

La empresa AERONOVA exige a los pilotos que contrata la habilitación profesional a través de la necesaria formación que la misma empresa imparte. La empresa adelanta el coste de la formación y después descuenta estas cantidades en las nóminas del trabajador en virtud de la suscripción de un pacto que tiene la visibilidad de "pacto de permanencia" pero en realidad no opera como tal.

The AERONOVA company requires the pilots it hires to have professional qualification through the necessary training that the same company imparts. The company advances the cost of training and then deducts these amounts from the worker's payroll by virtue of signing an agreement that has the visibility of a "permanence agreement" but in reality does not operate as such.
Pengaruh Rasio Keuangan Terhadap Pertumbuhan Laba
Authors: Lesmana Indra , Suprayogi Agus , Saddam Muhammad , Busro Muhammad Ali , Saifuddin Saifuddin
Published: June 2022

Penelitian ini bertujuan untuk mengetahui pengaruh rasio keuangan terhadap pertumbuhan laba pada perusahaan tambang batubara yang terdaftar di Bursa Efek Indonesia (BEI) periode 2017-2020. Variabel independen yaitu Rasio Keuangan, rasio keuangan yang digunakan adalah Current Ratio Net Profit Margin dan Debt to Eqity Ratio, sedangkan variabel dependen yang digunakan adalah Pertumbuhan Laba. Hasil yang diperoleh dalam penelitian ini adalah variabel Current Ratio dan Debt to Equity Ratio tidak berpengaruh terhadap pertumbuhan laba. Sedangkan variabel Net Profit Margin berpengaruh terhadap pertumbuhan laba. Secara simultan variabel Current Ratio, Net Profit Margin dan Debt to Equity Ratio berpengaruh terhadap pertumbuhan laba, besarnya koefisien determinasi (Adjusted R Square) adalah 22,3%. Hal ini berarti 22,3 persen variabel dependen yaitu pertumbuhan laba dapat dijelaskan oleh ketiga variabel independen, sedangkan sisanya 77,7 persen variabel pertumbuhan laba dijelaskan oleh variabel lain yang berada diluar penelitian ini.
Pengaruh Rasio Keuangan Terhadap Return On Assets Pada Perbankan
Authors: Marlinda Santi , Wahyudi Slamet , Hidayat Taufik
Published: June 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh Capital Adequacy Ratio (CAR), Loan to Depsit Ratio (LDR), Non Performing loan (NPL), biaya operasional pendepatan operasional (BOPO) terhadap Return On Assets (ROA) pada perbankan (studi pada bank umum yang terdaftar di Bursa Efek Indonesia selama periode tahun 2016-2020). Metode penelitian Asosiatif kuantitatif. Teknik analisis data dokumentasi yang bersumber dari laporan publikasi bank. Pengambilan sampel dilakukan secara purposive sampling dengan jumlah 10 bank. Hasil penelitian menunjukan bahwa Capital Adequacy Ratio (CAR) berpengaruh positif terhadap Return On Assets (ROA), Loan to Deposit Ratio (LDR) berpengaruh positif terhadap Return On Assets, Non Performing Loan (NPL) berpengaruh negatif terhadap Return On Assets (ROA), Biaya Operasional Pendapatan Operasional (BOPO) berpengaruh negatif terhadap Return On Assets (ROA). Secara simultan Capital Adequacy Ratio (CAR), Loan to Deposit Ratio (LDR), Non Performing Loan (NPL), dan Biaya Operasional Pendapatan Operasional (BOPO) memiliki pengaruh positif terhadap Return On Assets (ROA).
Evaluating the Experience of Sukuk Issuance in the World A Comparative Study of the Kingdom of Saudi Arabia and Malaysia
Authors: Amīn ʿUways , Jamāl Maʿtūq
Published: June 2022

This research sought to draw back the veil on the issuance of ṣukūk in the world and to examine it by comparing [the experiences of] Malaysia and Saudi Arabia. This is in order to map the future stage of Islamic ṣukūk issuance so that the instrument can properly develop and become the desired Islamic alternative. The research adopted the descriptive and analytical methods and reached a number of results. The most important is that the performance of ṣukūk in the financial market is somewhat acceptable (as has been established by the standard studies); however it has not risen to the level of the aspirations of the Islamic world nor the level of its potential. Moreover, the overall size and growth rate of ṣukūk have decreased since 2013 CE, and the future trends confirm that this decline will continue until 2030 if the situation continues as is, as evidenced by the outlook study. The study recommends that trading in Islamic financial instruments should be included in the Islamic and international securities markets in order to develop dealing in this market.
Economic Efficiency of Cryptocurrencies: Model of Bitcoin
Authors: A Al-shatir Muneer Maher , Abdullah Ahmed Sufyan , Shareef Suhail
Published: June 2022

Cryptocurrency is considered a significant financial ground-breaking financial product which has led to a new revolution in financial market, affecting many countries and institutions globally, in both the economic and regulatory level. The huge impact of its existence can be seen by the enormous volume of borderless transactions, which occasionally overwhelming the economic size of some countries. The objective of this article is thus, to explore the reality of cryptocurrency focusing on Bitcoin as a case study. Besides, the article also aims to measure the efficiency of the currency technically and economically as to make assumptions on the probable impacts should it happen that the currency is adopted in main stream monetary system. Eventually, the article concludes that the adoption of the currency (bitcoin) may lead to inefficiency of the economy due to its nature of being overly exposed to the volatile market forces without any supervision. The adverse economic condition such as the risk of piracy and loss of rights, can also be expected as until currently there is no legal jurisdiction that guarantees the rights, apart of the presence of in the currency itself