bluuebunny/crossref_metadata_2025 huggingface dataset:
ROLE OF ILAJ-BIL-GHIZA (DIETOTHERAPY) AS A PREVENTIVE THERAPY IN PREGNANCY INDUCED HYPERTENSION (PIH): A REVIEW
Authors: Imtiyazi N. , Ameen Furquan
Published: October 2021

The hypertension that is caused directly by gravid state is known as Pregnancy Induced Hypertension (PIH). It has an association with increased maternal morbidity and mortality. In classical Unani literature, hypertension is referred as Hejan of blood. Ibn-e-Sina (Avicenna) wrote in his book Al-Qanoon Fit Tib (Alcanon) that few times pregnant women may complain Warm-e-Qadam (Pedal Oedema). During labour, Tashannuj wa Tamaddud (Convulsions) may occur. Ilaj-bil-Ghiza (Dietotherapy) is a method of Unani treatment in which a specific diet is given for a specific disease. Dietary supplement of 400 IU Vitamin E and 1000 mg Vitamin C per day as antioxidant resulted in reducing oxidative stress, decreased endothelial activation and reduction in the risk of PIH by 61%. Specific diets mentioned in Unani medicine which contains Vitamin E and Vitamin C can be beneficial in PIH.
THE SURGICAL BILIO-DIGESTIVE BYPASS BEFORE CEPHALIC PANCREATICODUODENECTOMY, REPORT OF EIGHT CASES
Authors:   Surgery Department (I), Military Hospital, Rabat, Morocco, Faculty of Medicin, Sidi Mohamed Ben Abdellah University, Fes, Morocco., Najih Mohammed , Bouzroud Mohamed ,   Surgery Department (I), Military Hospital, Rabat, Morocco, Faculty of Medicin, Sidi Mohamed Ben Abdellah University, Fes, Morocco., El Mehdi Aboulfeth ,   Surgery Department (I), Military Hospital, Rabat, Morocco, Faculty of Medicin, Sidi Mohamed Ben Abdellah University, Fes, Morocco., Sidi Mohammed Bouchentouf ,   Surgery Department (I), Military Hospital, Rabat, Morocco, Faculty of Medicin, Sidi Mohamed Ben Abdellah University, Fes, Morocco., Hakim El Kaoui ,   Surgery Department (I), Military Hospital, Rabat, Morocco, Faculty of Medicin, Sidi Mohamed Ben Abdellah University, Fes, Morocco., Ahmed Bounaim ,   Surgery Department (I), Military Hospital, Rabat, Morocco, Faculty of Medicin, Sidi Mohamed Ben Abdellah University, Fes, Morocco.
Published: October 2021

The cephalic pancreaticoduodenectomy (CPD) has a universally high morbidity and surgery in patients with obstructive jaundice is associated with a high risk of postoperative complications especially in patients with high bilirubin levels. For this reason, endoscopic preoperative biliary drainage (PBD) has been proposed to improve the postoperative courses.. Nevertheless, this solution is not always feasible and the use of a surgical bilio-digestive bypass may be necessary, which may complicate a later surgical procedure.In this work we report a case series of patients who underwent CPD preceded by a double surgical bypass and we analyze its impact on morbi-mortality.
Students’ Motivation to Acquire English through Virtual Learning Midst Covid-19 Pandemic
Authors: Ikhwan Eisha Jamila Qomariyah , Andriyanti Erna
Published: October 2021

This research aimed to find out students’ motivation to acquire English as a foreign language through virtual learning midst Covid-19 pandemic. It involved 202 students spread throughout Indonesia. Data were collected by means of motivation questionnaires adopted from the Situational Motivation Scale (SIMS) of students’ motivation, i.e., instrumental motivation and integral motivation. The data were analyzed with descriptive statistics and Pearson’s Correlation on SPSS 22. The result shows that the students have a low level of motivation both for integrative and instrumental motivation to acquire English. The statistical calculation reveals that there is a correlation between the students’ motivation and virtual learning activity as shown by the level of significance 0,000<0,05 with the coefficient Pearson’s correlation of 0,282. There is no correlation between the students’ motivation and the Covid-19 pandemic as depicted by Pearson’s correlation of 0,062 with the significant level of 0,382>0,05. The research implies a need for a more innovative instructional design for virtual language learning to better improve students’ motivation to learn English during the Covid-19 pandemic.
Ana Dhei Dhato (An Analysis of Traditional Wedding Traditions at Rajawawo Village of Ende Regency)
Authors: Janggo Wendelinus
Published: October 2021

This research aimed to describe each process of ‘Ana Dhei Dhato’ and revealed its cultural meanings based on the perspective of people in Rajawawo village of Ende regency. The method of this research was descriptive qualitative research. In collecting the data, the researcher used interviews, note-taking, and recording. The data were analyzed through transcribing and translating. The analysis results show that ‘Ana Dhei Dhato’ is considered the most valuable type of wedding because of its complexity and peculiar characteristics. It can be seen from the way they run this kind of wedding ritual. Some cultural meanings are found in these wedding rituals and language spoken, such as religious meaning, social meaning, historical meaning, juridical meaning, and didactic meaning. Therefore, it is expected that people in Rajawawo village must consider ‘Ana Dhei Dhato’ as one of the most valuable cultural heritages and should also maintain its existence.
Language Politeness in the Javanese Verb Speech Level
Authors: Atmawati Dwi
Published: October 2021

The focus of this research was the use of Javanese verb forms. The problem was studied with a sociolinguistic approach. The object of this research was the selection of Javanese verb forms used by speakers in the Magelang region. The informants were children, adolescents, and adults, both male and female. The informants in this research were 50 Javanese speakers. Data obtained by the technique of listening, recording, and taking notes. The problem was studied using speech component theory and language politeness norms. This research used a qualitative descriptive method. Based on this research, it is known that some children and the younger generation are less able to choose the correct form of verbs related to the level of speech, for example, the words ‘siram’ (bath), ‘tindak’ (go), and ‘mireng’ (hear). These three words should refer to people with whom to speak and be respected, not to describe oneself. Using an inaccurate form of the verb can lead to the assumption that the speaker is impolite. Based on the findings in this research, it is hoped that there will be efforts, both in the domain of families, schools, stakeholders, and policymakers, to provide better education to speakers, especially children, and the younger generation. With better education, it is hoped that the younger generation will be able to understand well the proper use of verbs. Incorrect use of the verb form can indicate the impoliteness of the speaker.
Strategies Applied in Translating Information Technology (IT) Terms in Manual Books: Iphone 12 Pro and Samsung S20 FE
Authors: Pratiwi Eksanti Dwi , Khatib Ahmad Juma'
Published: October 2021

This research focused on the translation of technological terms from English into Indonesian in the translation of the manual book of iPhone 12 Pro and Samsung S20 FE. Descriptive The descriptive-analytical study was employed in this research. Then Chesterman’s translation strategies were used to find out how Information Technology (IT) terms were translated from English into Indonesian. The research finds that four translation strategies are used to translate the manual book of the iPhone 12 Pro and Samsung S20 FE from English into Indonesian. From the total 60 data, the four strategies are loan (35 data), calque (11 data), unit shift (13 data), and the least used strategies are information change (1 data). It can be concluded that the most frequently used strategies are loan (35 data), while the least used strategies are information change (1 data).
A Non-Peptidic MAS1 Agonist AVE0991 Alleviates Hippocampal Synaptic Degeneration in Rats with Chronic Cerebral Hypoperfusion
Authors: Xue Xiao , Duan Rui , Zhang Qiao-Quan , Wang Si-Yu , Gong Peng-Yu , E Yan , Zhang Ying-Dong , Jiang Teng
Published: October 2021

Background:

Chronic cerebral hypoperfusion (CCH) is a contributing factor for neurodegenerative diseases. As a recently identified heptapeptide of the brain renin-angiotensin system, angiotensin-(1-7) has been revealed to activate its receptor MAS1 and thus ameliorated cognitive impairments in rats with CCH. Since hippocampal synaptic degeneration represents an important pathological basis of cognitive deficits, we hypothesize that activating MAS1-mediated signaling may alleviate CCH-induced synaptic degeneration in the hippocampus.

Methods:

In this study, we tested this hypothesis and uncovered the underlying mechanisms in a rat model of CCH induced by bilateral common carotid artery ligation surgery. At one week after the surgery, rats received a daily intraperitoneal vehicle injection or a non-peptidic MAS1 agonist AVE0991 for 8 weeks. During this procedure, Cerebral Blood Flow (CBF) was recorded. The levels of MAS1, amyloid-β (Aβ), neuroinflammatory cytokines, glial cell markers, and synaptophysin in the hippocampus were assessed at the end of the treatment period.

Results :

We showed that AVE0991 significantly alleviated hippocampal synaptic degeneration in rats with CCH. This protection might be achieved by facilitating CBF recovery, reducing hippocampal Aβ levels, and suppressing neuroinflammatory responses.

Conclusions:

These findings indicate that MAS1-mediated signaling may represent a novel therapeutic target for CCH-related neurodegenerative diseases.
Extemporaneous Compounding: A Possible Trigger Tool to Detect Potential
Health Incidents
Authors: de Carvalho Mastroianni Patrícia , Toma Marina Massae , de Freitas Santana Gabriel , de Nadai Tales Rubens , Varallo Fabiana Rossi , de Lima Benzi Jhohann Richard
Published: October 2021

Background:

Extemporaneous compounding (EC) involves the preparation of a therapeutic
product for specific patient need. However, there is a potential relationship between this procedure
and the occurrence of health incidents (HI). The use of trigger tools increases HI identification.

Objective:

This study assessed the performance of EC as a trigger to detect potential health incidents
arising from this procedure.

Method:

A one-month observational and cross-sectional study was performed in internal
medicine ward and intensive care unit of medium-sized hospital. Data collection was carried out in
5 stages: all triggered patients with dysphagia or enteral feeding tube with prescription of EC were
included; EC executed in prescribed standardized drugs was observed; the procedure was compared
with the hospital guide and scientific literature; HI monitoring and their evaluation using
WHO and NCC MERP algorithms; a search for pharmaceutical alternatives (PA) that would avoid
the observed EC.

Results:

197 patients were recruited. Almost half of them were triggered by EC from 84 standardized
drugs. 48 patients met the inclusion criteria. 28 adverse drug reactions, 01 therapeutic ineffectiveness,
and 29 medication errors were identified. EC as a trigger tool showed a PPV value of
0.38. Only 24 drugs have PA available in the market, which could avoid one third of all observed
EC.

Conclusion:

It was possible to detect potentially HI in one of two patients with enteral feeding
tubes using EC as a trigger tool. The use of EC as a trigger tool contributes to identifying potential
HI arising from drugs, which have not gotten pharmaceutical alternatives to be administered via enteral
feeding tube.
Lipoxygenase Inhibitory Activity of Some Extracts Prepared from
Flaxseed (Linum usitatissimumv L.)
Authors: Jandali Raghad , Agha Mohammad Isam Hasan
Published: October 2021

Background:

Lignans are biologically important phenolic compounds that exist in different
levels of various plants; yet, flaxseed is one of the richest sources of such compounds. Lipoxygenase
enzymes are associated with many inflammatory-related diseases such as arthritis, allergic
asthma, psoriasis, cardiovascular disease, kidney disease, skin diseases, and neuropsychiatric disorders,
as in Alzheimer's disease. Not only are these enzymes involved in many types of cancers, but
they are also very crucial to find new LOX inhibitors to treat human diseases such as cancer or cardiovascular
disease. Screening for lipoxygenase inhibitory activities of flaxseeds lignans extracts in
various methods is reported in this work.

Methods:

Extracts of samples of flaxseeds (Linum usitatissmum) were prepared using the following
methods: a- extraction with continuous stirring with 80% ethanol, b- extraction with a mixture
of equal volumes of diethyl ether and ethyl acetate after direct acid hydrolysis, c- Extraction with
50% ethanol followed by alkaline hydrolysis. Total flavonoids, total phenolic of these extracts
were compared. The scavenging potential of free radicals was determined using the DPPH method.
The inhibitory potential against the lipoxygenase enzyme was determined by using the soybean
lipoxygenase enzyme.

Results:

The highest phenolic content was in the extract prepared with ethanol 80% with continuous
stirring, with phenolic content of (126.848 mg GAE /g). While the highest flavonoid was content
in the extract prepared with a mixture of equal volumes of diethyl ether and ethyl acetate after
direct acid hydrolysis, with flavonoid content reached (7.8 mg QE / g). Moreover, the scavenging
potential of free radicals expressed in terms of IC50 (μg/ml) showed extraction with a mixture of
equal volumes of diethyl ether and ethyl acetate after direct acid hydrolysis exhibited higher antioxidant
capacity (IC50=22.257±0.095 μg/ml) followed by 80% ethanol extract. The median inhibitory
concentration (IC50) was calculated according to the LOX enzyme inhibitory method. The IC50
value of a mixture of equal volumes of diethyl ether and ethyl acetate after direct acid hydrolysis
extract of flaxseeds is 73.689±0.585 μg/ml.

Conclusion:

The mixture of equal volumes of diethyl ether and ethyl acetate extract after direct
acid hydrolysis gives stronger scavenging potential of free radicals and lipoxygenase inhibitory effects
than the other extracts in this study. Therefore, according to the results we got in our study,
flaxseed extracts can be a potential source of novel therapeutics to treat many diseases related to
the LOX enzyme.
Research on the Influence of Temperature on the Performance of
Induction Motor
Authors: Zhang Wenzhong , Liu Ziyang , Zhao Qiang , Qiu Hongbo
Published: October 2021

Background: :

Induction motor plays a major role in various industries, and its importance
is increasing. Due to the environmental temperature or sealed working environment, heat generation
is generally severe. The heat exchange with the outside environment does not take place smoothly,
and the motor temperature increases. The performance of the induction motor is also significantly
influenced by the temperature. Therefore, it is necessary to study the influence of temperature on the
performance of induction motor.

Objective:

This study aimed to analyse the influence of temperature on induction motor. At different
temperatures, variation in performance parameters has been observed.

Methods:

Taking an 11 kW 1500r/min induction motor as an example, a two-dimensional transient
electromagnetic field model was established, and the correctness of the model was verified by experiments.
The motor starting performance, various losses and efficiencies under different temperatures
wereestimated.

Results :

As the stator and rotor resistance increased, the starting current decreased by 11.99% when
the internal temperature rose from 25°C to 150°C. When the internal temperature rose from 25°C to
150°C, the stator copper loss increased by 32.83%, and the rotor copper loss increased by 28.79%.
However, the core loss of the motor increased by 3W, and the motor efficiency decreased by 2.12%.

Conclusion:

When the temperature is different, the starting torque of the motor is almost unchanged,
and the starting current decreases with an increase in temperature. The stator copper loss
and rotor copper loss of the motor increase with the increase in temperature, while the core loss is
almost unchanged. In addition, the efficiency of the motor gradually decreases with the increase in
temperature.
The Effect of Life Kinetik Training Models to Improve Self-Confidence in Team and Individuals Athletes
Authors: Komarudin Komarudin , Mulyana Boyke , Novian Geraldi
Published: October 2021

Introduction:

Athletes are known to have confidence in individual abilities. Meanwhile, athletes that lack self-confidence often doubt their ability to perform at best. To increase self-confidence, it is necessary to train with the right model such as Life Kinetik training.

Objectives:

This study aims to examine the effect and differences in Life Kinetik and conventional training model to improve self-confidence in the team and individual athletes.

Methods:

This was an experimental study conducted using the “pre-posttest control group design.” The athlete’s confidence was tested pre and post-training treatments. Meanwhile, the study population, involving male athletes (mean age 17.4 ± 1.65 years), was from one of the state universities in Indonesia. Thirty-four tested athletes actively trained and competed in team sports, while thirty-two athletes engaged in an individual sport. Moreover, subjects were divided into two groups through random assignment, namely experimental and control groups. The experimental group used the Life Kinetik training model for eleven sessions, twice a week whereas, the control group utilized a conventional training model. Besides, data analysis was carried out using the t-test and MANOVA with SPSS version 24 for Windows.

Results:

The results showed that the Life Kinetik and conventional training model significantly increased self-confidence in the team and individual athletes. Furthermore, there were differences in the effect of the Life Kinetik and conventional training model on increasing the athlete's confidence in the team and individual sports.

Conclusion:

Based on the results, the Life Kinetik and conventional training models improve athletes' confidence. Meanwhile, there were differences in the effect of the Life Kinetik and conventional training models on increasing the athlete's confidence in the team and individual sports. The Life Kinetik training model is more effective compared to the conventional model. Therefore, the Life Kinetik training model can be recommended to train the self-confidence of athletes.
High-Occupancy Vehicle Lane Enforcement System
Authors: Jang Jinhwan
Published: October 2021

Introduction:

An automatic High-Occupancy Vehicle (HOV) lane enforcement system is developed and evaluated. Current manual enforcement practices by the police bring about safety concerns and unnecessary traffic delays. Only vehicles with more than five passengers are permitted to use HOV lanes on freeways in Korea. Hence, detecting the number of passengers in HOVs is a core element for their development.

Methods:

For a quick detection capability, a YOLO-based passenger detection model was built. The system comprises three infrared cameras: two are for compartment detection and the other is for number plate recognition. Multiple infrared illuminations with the same frequency as the cameras and laser sensors for vehicle detection and speed measurement are also employed.

Results:

The performance of the developed system is evaluated with real-world data collected on proving ground. As a result, it showed a passenger detection error of nine percent on average. The performances revealed no difference in vehicle speeds and the number of passengers according to ANOVA tests.

Conclusion:

Using the developed system, more efficient and safer HOV lane enforcement practices can be made.
Effectiveness of a Mindfulness-Based Mobile Application for the Treatment of Depression in Ambulatory Care: Protocol for a Randomized Controlled Trial (Preprint)
Authors: Sarlon Jan , Doll Jessica P K , Schmassmann Aline , Brand Serge , Ferreira Naomi , Muehlhauser Markus , Urech-Meyer Stefanie , Schweinfurth Nina , Lang Undine Emmi , Bruehl Annette Beatrix
Published: October 2021

BACKGROUND

Patients with major depressive disorder (MDD) often experience relapses despite regular treatment with pharmacotherapy and psychotherapy. Further, long waiting lists and more demand than treatment capacity characterize ambulatory settings. Mindfulness-based interventions proved to be effective in relapse prevention in MDD. Next, mindfulness-based interventions in the form of free mobile applications can be an effective augmentation of the treatment as usual and can fill a gap in ambulatory care.

OBJECTIVE

Given this background, the aim of this randomized controlled study is to assess the effectiveness of additional MBI via a mobile app on the symptom severity and stress levels, compared to treatment as usual.

METHODS

A total of 140 individuals with MDD will be randomly allocated to the intervention or control condition. The intervention consists of the daily use of the mindfulness mobile application Headspace for thirty days (up to 10 minutes a day). The control condition will be treatment as usual. At baseline and four weeks later, the following key outcome dimensions will be assessed: self-rated (Beck Depression Inventory) and experts’ rated symptoms of MDD (Hamilton Depression Rating Scale); secondary outcome variables will be blood pressure, heart rate, and respiratory rate and changes in tobacco and alcohol consumption and medication as a proxy of perceived stress.

RESULTS

This study was funded in February 2021 and approved by the institutional review board on April 15, 2021, and it started in May 2021. As of December 2021, we enrolled 30 participants. The findings are expected to be published in spring 2023.

CONCLUSIONS

We hypothesize that compared to the control conditions, individuals with MDD of the mobile app-condition will have both lower self- and experts’ rated symptoms of MDD and more favorable stress-related levels. While the risk for medical events is low, the immediate benefit for participants could be a decrease in symptom severity and reduction of the stress level.

CLINICALTRIAL

Clinical Trials.gov NCT05060393; https://clinicaltrials.gov/ct2/show/NCT05060393.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/33423
A formação em educação literária na construção do professor como interlocutor qualificado
Authors: Pereira Maria João , Cosme Ariana , Malato Maria Luísa
Published: October 2021

Este artigo apresenta um projeto de pesquisa-ação no âmbito de um curso de formação de professores no campo da Educação Literária, junto de cinco turmas de professores na cidade do Porto (Portugal) e cujo objetivo visava analisar e produzir conhecimento sobre as práticas docentes e o potencial pedagógico da Educação Literária. Assim, refletimos sobre a importância dos paradigmas pedagógicos pela forma como influenciam a ideia de Escola, o papel dos professores na definição da Educação Literária e sua importância enquanto instrumento pedagógico agregado à construção do programa. É nesta linha que se abrem caminhos para a reflexão sobre a Educação Literária enquanto espaço de promoção de democracia, motivador para a construção de cidadãos críticos sobre o mundo envolvente e que se reconhece a formação de professores como parte imprescindível de uma ação pedagógica reflexiva, apelando à ação de um professor enquanto “interlocutor qualificado” (COSME, 2009). Em síntese, podemos concluir que, através da cooperação entre professores participantes e investigadoras, tivemos aqui a oportunidade para aliar perspetivas e experiências sobre conceções e práticas em Educação Literária. Os discursos sobre as práticas são oportunidades para refletir sobre as próprias. Consideramos também que o que definimos como prática traça linhas de ação no trabalho pedagógico, com as suas estratégias e instrumentos específicos.
Calidad de vida relacionada con la salud y percepción de amenaza de la enfermedad en pacientes con enfermedad renal crónica avanzada
Authors: Lacomba-Trejo Laura , Mateu-Mollá Joaquín , Carbajo Álvarez Eva , Poves Gómez Marta , Galán Serrano Antonio
Published: October 2021

Introducción:
La enfermedad renal crónica avanzada (ERCA) puede impactar notablemente lacalidad de vida relacionada con la salud (CVRS) de las personas que la padecen. Además, la per-cepción sobre lo amenazante que es esta enfermedad para su vida puede impactar notablementela salud física y emocional de los pacientes.
Objetivos:
Valorar la CVRS y la percepción de amenaza de la enfermedad en pacientes con ERCAy evaluar las asociaciones entre las variables de estudio.
Materiales y métodos:
Estudio transversal realizado en 70 pacientes (80 % varones) de entre 38y 88 años (M=68,88; DT=9,98) mediante dos instrumentos: el cuestionario de calidad de vida enenfermedad renal versión abreviada (KDOQL- SF36) y el cuestionario de percepción de amenaza de enfermedad (BIPQ). Se realizó un análisis descriptivo de los datos mediante el programaestadístico SPSS 26.0 y usando los estadísticos pruebast,dde Cohen y correlaciones de Pearson.
Resultados:
Los participantes mostraron una gran afectación de su CVRS y una percepción ne-gativa de la enfermedad, siendo los peores indicadores los encontrados en mujeres. Una peorpercepción de la enfermedad se asoció con mayor afectación de la CVRS
Conclusiones:
La percepción de los pacientes sobre su salud puede afectar la adherencia terapéutica,por lo que es necesario implementar programas de intervención que incidan en ella y favorezcan lasalud física y mental de los pacientes.
Importancia de un modelo de nefroprevención adaptado para Colombia
Authors: Abuabara-Franco Emilio , Bohórquez-Rivero José , Restom-Arrieta José , Sáenz-López José , Gómez-Franco Alicia , Navarro-Quiróz Roberto
Published: October 2021

La enfermedad renal crónica es una afección de elevada incidencia y prevalencia, que representa un importante problema de salud pública a nivel mundial. Se encuentra dentro de las principales causas de muerte tanto en Colombia como en el resto del mundo y presenta una gran carga social y económica; similar a la de otras enfermedades crónicas como la Hipertensión Arterial y la Diabetes Mellitus. Actualmente, los gobiernos han realizado esfuerzos para moderar sus estadísticas; sin embargo, estos no han sido lo suficientemente sólidos para mantener bajo control el efecto que ejercen dichas enfermedades en la salud de las personas, por lo cual se hace imprescindible fortalecer las acciones que fomenten dicho control. El objetivo de esta revisión es resaltar la importancia de un modelo de nefroprevención que se adapte a nuestro país; que permita la detección oportuna y la prevención de los factores de riesgo cardiovasculares y renales, y que facilite el diagnóstico precoz de la enfermedad renal crónica en aras de eludir su progresión y sus consecuencias potencialmente letales.
Modelo ideal de nefroprevención para Colombia
Authors: Zakzuk Perez Juan Pablo , Vargas Torres Josber , Urzola Suárez María Rosa , Piñerez Ochoa María Paula , Arenas Hoyos German , Ocampo Henao Oscar
Published: October 2021

La enfermedad renal crónica (ERC) es una patología altamente prevalente en países en vía de desarrollo como Colombia, en donde afecta a gran parte de la población. Esta es una enfermedad que afecta la calidad de vida y la longevidad de los pacientes, así como los costos del sistema de salud.
La ERC tiene un carácter progresivo e irreversible, por lo que intervenirla en etapas tempranas resulta ser una medida altamente costo-efectiva; a partir de esto surge el concepto de nefroprevención, mediante la cual, teniendo en cuenta los niveles de prevención primaria, secundaria y terciaria, se puede lograr una identificación precoz y la interrupción o enlentecimiento de la progresión, y además se puede implementar un manejo oportuno e integral del daño renal según el estadio de la enfermedad. Esto es posible haciendo una búsqueda activa de casos, realizando pruebas de cribado y haciendo intervenciones interdisciplinarias que incluyan educación de la población y del personal en salud, para así promover el autocuidado y realizar un seguimiento que impacte de forma positiva en la calidad de vida de los pacientes, en los desenlaces de la enfermedad y en la economía de los países en vía de desarrollo, los cuales deben optimizar sus limitados recursos e invertir en los procesos que generen mayor costo-efectividad.
Proteoma urinario en la enfermedad renal diabética. Estado del arte
Authors: Rico Fontalvo Jorge Eduardo , Daza Anedo Rodrigo , Raad Sarabia María , Pájaro Galvis Nehomar , Bello Espinosa Ariel , Uparella Gulfo Isabella , Pérez Calvo Christian , Pomares Lara Alonso , Mondol Almeida Zulay , Vergara Serpa Oscar , Berrocal Martinez Carlos , Collazos Torres Luis Adolfo , Ruiz Pastrana Karen
Published: October 2021

La enfermedad renal diabética (ERD) es la principal complicación microvascular de los pacientes con diabetes mellitus; esta es una entidad que genera un aumento significativo en la mortalidad de origen cardiovascular de este grupo de pacientes, aunque su diagnóstico temprano impacta de forma significativa en la evolución a enfermedad renal terminal y, por lo tanto, en la mortalidad. La detección de albuminuria en la orina y el deterioro de la tasa de filtración glomerular estimada son las principales técnicas diagnósticas que se utilizan en la práctica clínica para establecer la presencia de ERD; sin embargo, estas tienen limitaciones y por lo tanto es importante resaltar que el daño renal suele ser irreversible una vez están presentes. Durante los últimos años, numerosos estudios se han enfocado en detectar nuevos biomarcadores para detectar ERD y es aquí donde aparece como nueva herramienta la proteómica urinaria, una tecnología emergente que permite identificar en una muestra de orina proteínas que sugieren la presencia de esta enfermedad de manera temprana. Asimismo, el descubrimiento de biomarcadores basados en proteómicos representa una estrategia novedosa para mejorar el diagnóstico, pronóstico y tratamiento de la nefropatía diabética; sin embargo, los enfoques basados en la proteómica aún no están disponibles en la mayoría de los laboratorios de química clínica
Features of functional reserves of the cardiovascular system in cadets of the maritime university in conditions of long-term navigation
Authors: Gudkov A. B. , Shcherbina F. A. , Popov O. N. , Chashchin V. P.
Published: October 2021

Aim: to reveal the features of cardiovascular system functional reserves in naval cadets under the conditions of a long voyage.

Materials and methods. 70 cadets undergoing training and sailing practice for 165 days on Sedov training and sailing ship were studied. Cardiovascular system reserves were determined once a month indices before taking over the watch. The results were elaborated using the SPSS program, v 17.0 (IBM).

Results and their discussion. On the first, second, and third months of the voyage, the naval cadets retained the functional reserves of the cardiovascular system, which is indicated by the typical normotonic reaction in its activity in response to physical activity.

On the fourth and fifth, the cadets showed signs of a decrease in the reserves of the cardiovascular system, which is manifested by a slower recovery after standard physical activity, a decrease in the inotropic reserve index and an increase in the chronotropic reserve index.
Relationship between psychovegetative status dysfunction and markers of the early formation of the atherosclerotic process in flight personnel in the Far North
Authors: Zakrevsky Yu. N. , Gertsev A. V. , Boutikov V. P. , Manuilov V. M.
Published: October 2021

The aim of this work is studying the influence of the severity of dysfunctions on the part of the central and autonomic nervous systems on the atherosclerotic process in hypertension in flight crews with concomitant traditional factors of cardiovascular risk (abdominal obesity) serving in the Far North by the authors.

Materials and methods. A clinical examination was carried out on 54 patients (men) aged from 33 to 42 years, from among the military personnel of the aviation personnel of the Northern Fleet naval aviation, the average age of the examined was 37.4±4.6 years. The following groups of patients were formed: 1st (n=26) — flight crew specialists serving in the Far North, with first degree abdominal obesity, first stage hypertension and moderate astheno-neurotic disorders (main group); 2nd (n=14) — flight crew specialists serving in the Far North, with first degree abdominal obesity, first stage hypertension in comorbidity with mild astheno-neurotic disorders; Group 3 (n=10) was represented by flight crew patients with the first stage of hypertension with initial manifestations of psychovegetative dysfunctions (control). We assessed the qualitative and quantitative paired correlations between the state of the psychological status, regulation of the neuropsychic adaptation system, markers of early formation of atherosclerosis, and indicators of the average daily blood pressure level.

Results and their discussion. It was found that the severity of disorders of the asthenovegetative spectrum in the examined groups has a negative direct pathological effect on quantitative and qualitative paired correlations between indicators characterizing the state of psychophysiological status, markers of early formation of the atherosclerotic process, and values of average daily blood pressure monitoring. The results obtained make it possible to summarize that the more pronounced the disturbances in the functioning of the central and autonomic nervous systems in hypertension in persons from the flight crew, the more significant the shifts towards atherogenicity of indicators reflecting the activity of the atherosclerotic process and the more unfavorable outcome in the course of cardiovascular pathology in such patients.
Study of renal function indices to determine hypoxic hypoxia resistance in divers
Authors: Zverev D. P. , Myasnikov A. A. , Shitov A. Yu. , Andrusenko A. N. , Chernov V. I. , Klenkov I. R. , Israfilov Z. M.
Published: October 2021

Aim: using oral stress kidney tests to reveal changes in renal function and water-electrolyte metabolism in divers with different initial resistance to hypoxic hypoxia.

Materials and methods. 44 men were studied. All subjects were evaluated for their initial resistance to hypoxic hypoxia. Oral renal stress tests were performed to determine the status of kidney function.

Results and their discussion. For the selection of divers, it is necessary to carry out oral stress tests with water, 10% potassium chloride solution and 7.5% calcium lactate solution. In divers with low and medium resistance to hypoxic hypoxia, there is a deterioration in the calcium and potassium uretic function of the kidneys after oral stress renal tests. The method for determining the resistance of divers to hypoxic hypoxia should be supplemented by the regularity developed by us.
Characteristics of the weather and climatic conditions of the Arctic zone of the Krasnoyarsk Territory by bioclimatic indices
Authors: Rakhmanov R. S. , Bogomolov E. S. , Narutdinov D. A. , Razgulin S. A. , Ashina M. V.
Published: October 2021

Aim. Assess the health risk of a cold environment by bioclimatic indices characterizing weather and climatic conditions in the Arctic zone of the Krasnoyarsk Territory.

Materials and methods. The mean monthly daily ambient temperature, wind speed and relative air humidity were determined. The body cooling conditions integral index (BCCII) and the wind-cold index (WCI) were calculated.

Results and their discussion. Using the BCCII from 4 to 6 months a year at Cape Chelyuskin, the critical risk of frostbite in exposed areas of the body determined at Dixon Island from 4 to 5 months a year; in July and August, the indicator values reached the lower border of the “moderate risk”. Using the WCI, an uncomfortable cold environment was determined, respectively, 2 months and 4 months, a very cold — 3 months and 2 months, and an extremely cold — 3 months and 2 months.

Conclusion. The advantage of using BCCII rather than WCI is shown, since on its basis the criteria for safe working conditions in an open area are determined. To interpret the value of “no risk” while using WCI, it is necessary to know the period of the year, in which the weather and climatic conditions are assessed as a cold environment.
Experience in conducting a special tactical exercise of the forces and means of the Ministry of emergency situations of Russia with a massive influx of victims of an emergency of a biological and social nature (terrorist act)
Authors: Aleksanin S. S. , Rybnikov V. Yu. , Nesterenko N. V.
Published: October 2021

Aim. To summarize the experience of conducting special tactical exercises of the forces and means of the EMERCOM of Russia in the event of a massive admission of victims of an emergency of a biological and social nature (terrorist act) to a multidisciplinary hospital and an airmobile hospital of the EMERCOM of Russia.

Materials and methods. The normative documents and experience in response of the EMERCOM of Russia during the training period with a massive influx of victims were analyzed.

Results and their analysis. The results of special tactical exercises, the experience of the deployment and actions of the forces and means of the EMERCOM of Russia during the mass admission of victims of a terrorist act to a multidisciplinary hospital and an airmobile hospital of the EMERCOM of Russia are presented. For evacuating 50 victims, ambulance aircraft (MI-8 helicopter), ambulances and cars were used. The exercise was attended by over 300 people, including observers and participants in the exercise, victims.

Conclusion. The data obtained are an important basis for maintaining the readiness of the forces and means of the Russian Emergencies Ministry to respond to emergencies.
On the importance of monsoon rainstorm impact period in soil salinization
Authors: Ke Zengming , Liu Xiaoli , Ma Lihui , Jiao Feng , Tu Wen , Feng Zhe , wang zhanli
Published: October 2021

Abstract: Long-term soil salt accumulation could lead to salinization.
Aimed to prevent soil salinization, we investigated soil salt dynamics,
its interface with the groundwater table, rainfalls duration and the
impact periods when salt is mostly accumulated. Total soil salt
accumulation and dynamic distribution were monitored in the 0–80 cm
layer in alluvial farmland from 2018 to 2020. We found soil salt
contents increased by 0.15 g kg–1 and 0.07 g kg–1 in the 0–40 and
40–80 cm soil layers, respectively, which indicated that soil
salinization occurred. We defined the rainstorm impact period (RIP) as
period when soil salt dynamic distribution was affected by rainstorm
event. The salinity time-trend during RIP was sequentially characterized
by a first salt leaching, followed by a rapid and then slow salt
accumulation, which took the first 4 days, from day 4 to 10, and then
beyond, respectively. In the first leaching stage, salt migration
content was determined by rainfall (P < 0.05) which could
leach 41.5% of salt on average in the whole soil layer. In the rapid
accumulation stage, lots of salt accumulated due to high
evapotranspiration and shallow groundwater table. In the slow
accumulation stage, salt accumulation rate was inhibited by deeper
groundwater table. In addition, the total accumulated soil salt in the
whole soil layer increased by 0.14 g kg–1 in the RIPs, which comprised
only 14.5% of the overall study period, but the value accounted for
63.6% of the salt accumulation, thereby indicating that RIPs were the
main periods when salt accumulated during the soil salinization process.
Our results provided insights into soil salt dynamic distribution during
RIPs, thereby facilitating the effective prevention and control of soil
salinization.
Brain Mineralocorticoid receptor in health and disease: from molecular signaling to cognitive and emotional function
Authors: Paul Susana , Wingenfeld Katja , Otte Christian , Meijer Onno
Published: October 2021

Brain mineralocorticoid receptors (MR) mediate effects of aldosterone in
relation to salt homeostasis, and of glucocorticoid stress hormones
corticosteroids in the context of stress adaptation. Brain stem MRs
respond to aldosterone, while forebrain MRs mediate rapid and delayed
MR-mediated glucocorticoids effects in conjunction with the
glucocorticoid receptor. MR-mediated effects depend on gender, genetic
variations and environmental influences. Disturbed MR activity by
chronic stress or in certain (endocrine) diseases can cause deleterious
effects on affective state, cognitive and behavioural function in
susceptible individuals. High MR activation may have protective effects
in healthy individuals, whereas dysregulated high MR activity during a
stress response would require treatment with mineralocorticoid receptor
antagonists (MRAs). Here, we discuss recent pharmacological and genetic
developments, from the molecular underpinnings of MR signaling and
function, to pharmacological interventions in the clinic. Improved
understanding of MR dependent pathways will help to improve
glucocorticoid therapy, unwanted side effects and psychiatric symptoms.
Effect of a social skills program on the improvement of the organizational climate of educational institutions for schools
Authors: Vásquez-Panduro Imelda , López-Novoa Ibis , Padilla-Guzmán Manuel , Gallarday-Morales Santiago
Published: October 2021

The article set out to determine the effect of a social skills program on improving the organizational climate of the professors and administrative workers of the Germán Tejada Vela educational institution in Moyobamba. The research was quantitative, quasi-experythmental design, experimental type; the population consisted of 180 teaching and administrative workers; the sample was 90. The social health program was developed through workshops with the experimental group and a questionnaire was applied about the organizational climate as a pretest and post-test to both groups. The results were processed by the SPSS version 20.0 statistical program; analysis of the results, itis concluded that the effect of the implementation of a social skills programme on the improvement of the organizational climate of the teaching and administrative workers of that institution is positive and significant.
Developing a conceptual framework for (educational service) marketing competencies of faculty members
Authors: Shirpour Mohsen , Sattari Sadraddin , Vazifeh Rasool
Published: October 2021

The present study was to establish a conceptual framework for faculty members' personal marketing (training services) competencies. Assuming that universities are the highest institutes of learning with the aim of promoting knowledge transfer, providing human resource training in various fields of science and technology, providing higher education and research services; They need competent faculty members to achieve these goals. In this qualitative study, documentary analysis was used to evaluate all books, print and electronic resources and resources in the fields of marketing and branding, using note-taking forms as data collection tools. Qualitative analysis and further coding were used to analyze the data. The results of expert opinions also showed that one of the most important personal marketing competencies of faculty members is a significant relationship between knowledge competencies and behavioral competencies.
The development of preschoolers’ cognitive and communicative activity in the process of educational and research activities in nature
Authors: Karapuzova Iryna , Sulaieva Nataliia , Manzhelii Nataliia , Vashak Oksana , Fazan Tetiana
Published: October 2021

Preschool education remains one of the strategic directions of state policy in the field of education. The current state of development of society in Ukraine opens considerable opportunities for updating the education content based on the principles of child-centeredness, humanization, and integration. The main aim of this article is to consider an essential issue of preschool education. As methods, analysis of productive activities (results of completed tasks), observation of children, and conversation with them are utilized. It is the organization of educational and research activities in nature as a means of developing preschool children’s cognitive and communicative activity. Emphasis is put on their role in preschoolers’ personal development, the feasibility of its implementation in preschool education. It is concluded that increasing the preschoolers’ level of cognitive and communicative activity is possible using mnemonic tables and fairy tales about nature.
Communicative-speech future educator training for social adaptation of 5- to 7-year-old children by means of modern art
Authors: Zimakova Liliya , Kramarenko Valentyna , Kovalevska Natalija , Tupytsya Oleksandr , Mokhirieva Yuliia
Published: October 2021

The article clarifies that in Ukraine the professional communicative-speech future educator and primary school teacher training for social adaptation of 5- to 7-year-old children is relevant and important. The efficient role of modern art in the social adaptation of children has been studied. The model of professional communicative-speech future educator training for social adaptation of children by means of modern art with the following structural components is developed: the stimulating and motivating component, the semantic component, the operative and action component, the monitoring and regulating component, and the assessment and result component. Based on the results, the presented model of professional future preschool teacher and primary school teachers training is effective, and the artistic and pedagogical approach increases the level of future educators’ communicative-speech development, socio-pedagogical competence and socio-artistic pedagogical sensitivity, which generally contributes to the formation of their professional competence.
The influence of virtualization and municipal museums in the activities on the historical education of citizens
Authors: Vapnyarskaya Olga Igorevna
Published: October 2021

The purpose of the study is to reveal the influence of virtualization on the role and contribution of municipal museums to the activities of the historical education of citizens and the development of cultural tourism. Based on the analysis of scientific literature, the study examines the features of the functioning of municipal museums and analyzes the phenomenon of its virtualization. The study deals with the transformation of municipal museums into territorial socio-cultural centers. Based on the analysis of the work of the Museum Association "Museums of the Korolev science city", the contribution of municipal museums to the historical education of the population has been analyzed, recommendations for the creation of virtual exhibitions based on the website of the said Museum Association have been proposed. In the end, it was concluded that virtualization of municipal museums is a modern advertising tool that informs about the tourist benefits of the city and the region, increases the possibilities of museums for the historical education of citizens, and forms a new type of motivation for cultural tourism.
Museum pedagogy in education: educational, historical, and pedagogical aspects
Authors: Nataliia Filipchuk , Yarina Kvasetska , Ludmila Bazyl , Valeriy Orlov , Myroslava Vovk , Galina Zahaiska
Published: October 2021

At the present stage of civilizational development, characterized by numerous transformations in the historical-political, socio-economic, cultural, scientific, and educational spheres of social progress, the importance of using the results of pedagogical innovation in continuing education is emphasized. The study's aim is to consider the experience of using museum pedagogy based on education and analyzes this phenomenon in terms of historical and pedagogical aspects. To meet the objective of the study, the descriptive method is utilized. Based on the results obtained, it can be concluded that the mission of museums is to increase the level of knowledge and moral and spiritual education. The authors state that the priority approach of the state cultural, scientific, and educational policy should be the effective use of museum activities for the public good. Education requires the active introduction of museum pedagogy to improve the educational process.