bluuebunny/crossref_metadata_2025 huggingface dataset:
Memorial War in the Modern World: History and Theory
Authors:   North Caucasus Mining and Metallurgical Institute, Chedzhemov Sergey R.
Published: June 2022

2022 marks the anniversary of the Battle of the Caucasus, one of the fateful battles of the Great Patriotic War. The multinational Russian people are sensitive to the historical memory of their heroic ancestors, the great feat of the Soviet people who saved Europe and the whole world from fascist enslavement. This fully applies to the residents of the Republic of North Ossetia-Alania. However, today in the world the “cold” war and the détente of international tensions have been replaced by the “memorial” war. Historical reality and people’s memory are distorted, monuments to the dead are overthrown. Scientists engaged in the analysis of historical and legal problems need to do everything possible to defend historical truth and expose lies and distort the results of World War II. The authors, based on the analysis of normative and historical sources, focus on the problems of the so-called “memorial war”, the factors that determine the current state of our society, which needs to build up and modernize the system of patriotic educational work based on historical search. The article applies an interdisciplinary approach that allows using the methods of historical and historical-legal research, which is consistent with the order of the Ministry of Education and Science of the Russian Federation dated November 10, 2017 №. 1093 on the approval of a new nomenclature of scientific specialties. This makes the issues raised in the article very relevant. The materials of the article can be used in the methodology of teaching historical disciplines, conducting educational work in educational institutions.
Development of the Cadets’ Regulative Skills at Practical English Classes by a Means of Formative Assessment Technology
Authors:   Yaroslavl Air Defense Military College, Orekhova Yuliya M.
Published: June 2022

The new paradigm of education requires teaching stuff to search for efficient ways of forming of the key competences integral to personal and professional development of future officers of the Russian Army. Due to this reason, the search for the brand new assessment methods and technologies used in measuring cadets’ personal achievements in a military college is a challenging problem of foreign language learning theory and practice. The implementation of the modern assessment techniques involves the development of students’ regulative skills at foreign language classes and meets the requirements of the new federal educational standard to the teaching process in a higher educational institution, provides the sustained personal growth conditions and encourages cadets to conscious learning activities. The present article is devoted to the analysis of the formative assessment didactic potential relating to the field of foreign language teaching. The author proves the effectiveness of its use at the English classes as a means of improving cadets’ monitoring, evaluation and reflexive skills. Formative assessment is considered as a learning technology necessary for cadets’ personal development and improving the quality of foreign language learning through providing the feedback from all the parties involved in the educational process organization. The advantages of formative assessment in comparison with traditional methods of assessment are given. The cadets’ regulative skills developed by means of this technology at the English classes are also listed. The author provides the examples of the main formative assessment techniques implementation (criteria-based assessment, self-report, survey, etc.) at the English practical classes. The article contains the figures and tables which demonstrate the implementation of formative assessment.
The National Liberation Struggle and the Declaration of Independence of South Ossetia in the Late 80s - Early 90s. 20th Century
Authors:   North Ossetian State University named after K.L. Khetagurov, Shavlokhov Georgy K.
Published: June 2022

The article deals with issues related to the history of the creation of the statehood of the Republic of South Ossetia from the time of the beginning of the destruction of the Soviet Union until its complete collapse. The relevance of the article is due to the growing interest in the historical conditions for the construction of statehood in South Ossetia, its features and characteristics. In addition, the events of this important stage in the recent history of the South Ossetian people are still insufficiently covered in the domestic scientific literature. Particular attention is paid to the political processes of the late 80s - early 90s. of the last century, which radically changed the situation in South Ossetia. It is noted that the invasion of the Georgian armed formations into the territory of South Ossetia, as well as the facts of the genocide carried out against them by the Georgian Mensheviks in the summer of 1920, preserved in the historical memory of the South Ossetian people, predetermined the impossibility of further being part of the Georgian state, aggressively disposed against national minorities. Accordingly, the population of South Ossetia came to the full realization of the need to declare independence, as the only way to save themselves from physical destruction by Georgian nationalists. Great importance in the work was given to the consideration of a set of issues related to the political, legal and historical justifications for the declaration of independence of the Republic of South Ossetia. In particular, it is stated that the implementation of the strategic course towards full independence and sovereignty of the republic, self-determination of the South Ossetian people was carried out in accordance with the union legislation in force at that time. As a result, the people of South Ossetia, who suffered heavy human losses and destruction during the national liberation struggle, retained their historical lands, the article emphasizes.
Redes sociales y producción del sujeto criminal en el contexto urbano. Comentario a Incivil y criminal, de Andrea Aguirre
Authors: Eguiguren María Mercedes
Published: June 2022

s. r.
La representación internacional de Colombia y el Tratado con las Provincias Argentinas, 1825
Authors: Kloster Mariano
Published: June 2022

Este artículo estudia el tratado entre la República de Colombia y Buenos Aires, armado en 1823, y ratificado por el Congreso Constituyente de las Provincias Argentinas en 1825. Las discusiones en torno a este acto muestran dos fenómenos inherentes al reconocimiento internacional: por un lado, la dinámica del proceso de nacionalización de la soberanía en las Provincias Argentinas; por otro, la cuestionada superposición de cargos del deán Gregorio Funes quien era, simultáneamente, diputado por la provincia de Córdoba y encargado de negocios de Colombia frente a las Provincias Argentinas.
Quito como escenario de construcción estatal de la delincuencia entre 1960 y 1980
Authors: Clark Kim
Published: June 2022

s. r.
Alfredo Bosi: el brillo de un legado
Authors: de Salles Oliveira Cecilia Helena
Published: June 2022

s. r.
The Effect of Limestone and Fly Ash on Clay Stabilization on CBR and Soil Compressive Strength
Authors: Lonarissa Harditya Putri Vandika Nadia , Syafwandi Syafwandi
Published: June 2022

The subgrade in the road access construction project must have a strong soil bearing capacity so that it can withstand the load on it. Clay soil has high water content and expands easily. Various ways have been done to overcome it, one of them is by improving the original soil properties using the stabilization method. The research conducted is the stabilization of expansive clay soil using fly ash and limestone with a percentage of fly ash 5%, 10%, 15%, 20% fly ash and 25% limestone. Existing soil used from a wellpad construction project, in Ujung Pangkah, Gresik, East Java. The tests carried out are specific gravity, Atterberg, compaction, CBR and UCT tests. The CBR test was conducted to determine the appropriate CBR value to support DDT. The compressive strength of the soil was tested using the UCT test. The results of the study of the effect of fly ash and limestone are an increase in the dry weight of the soil and a decrease in soil water content. The increase in CBR and maximum soil compressive strength with a mixture variation of 20% fly ash + 25% limestone, Qu is 2.98 kg/cm 2 and CBR is 10.56%. This is due to a decrease in the water content thereby increasing the dry weight of the soil.
AKSI BERSIH PANTAI DALAM MENINGKATKAN LINGKUNGAN BERSIH DI PANTAI SEGER KUTA LOMBOK
Authors: Mardiana Baiq Wirian , Sari Dwi Sonia , Hemamalini Hemamalini , Yasmin Lale , Adistira Lalu Gede A. K. D. , Sari Lita Purnama , Ludyasari Septiyana Tri , Sumbawati Yuyun , Setiawan Heri
Published: June 2022

The rapid development of tourism in the Mandalika SEZ area has various positive and negative impacts. The negative impact is in the form of various problems, one of which is the problem of waste, such as in the Seger beach area of ​​Kuta, Lombok. One of the things that can overcome this is, it takes awareness of the local community and visitors to keep the environment clean. Efforts that can be made to overcome these problems are, the Unram Integrated Community Service Team concluded to carry out weekly routine cleaning or beach clean-up actions around Seger beach. This activity aims to increase public awareness and visitors to maintain cleanliness and provide an understanding that by disposing of garbage in its place can make the environment cleaner so that the beauty of the beach can be enjoyed comfortably. The methods used are direct observation, interviews, coordination, preparation, and implementation of beach cleaning as well as waste disposal. The Unram team consists of 15 students. Through weekly clean-up activities, the cleanliness around the beach is maintained and there is an increase in public and visitor awareness in maintaining cleanliness. The results were quite good, so that the community members took part in the Seger beach clean-up activities. In the future, it is hoped that there will be complete facilities and technical waste transportation so that the cleanliness of the Seger beach is maintained.
La lucha y la alianza del 66. La opinión en el periódico La Patria en la creación de Risaralda
Authors: Vallejo Giraldo Camilo
Published: June 2022

Esta reflexión se orienta a analizar cómo el periódico La Patria, en su momento, como el principal medio de comunicación de la región del Eje Cafetero, jugó un rol fundamental en la creación del Departamento de Risaralda. Con sus opiniones, más allá de lo anecdótico, hace presencia en los dos momentos de la crisis, en tanto evento histórico: uno comunicativo abierto a la opinión pública, y otro político como contexto de las negociaciones del conflicto. Se pre- tende re-significar el manejo de poder de las elites de las dos capitales: Manizales y Pereira en el marco de la disputa que llevo a la escisión territorial.
Manifestaciones de la autorregulación emocional en niños y niñas de educación inicial
Authors: Franco Cardenas Beatriz Elena , Menjura Escobar María Inés
Published: June 2022

El artículo describe los resultados de un estudio cualitativo de las manifestaciones de autorregulación emocional en actividades lúdicas de niños y niñas de 4 a 5 años de una institución de educación preescolar del municipio de Armenia.
La interacción de niños y niñas permitió reconocer y analizar las manifestaciones de la regulación emocional y concluir que el juego no solo es fuente de diversión, sino una valiosa estrategia para favorecer procesos de autorregulación emocional en la edad preescolar por cuanto estimula los mecanismos y estrategias para resolver retos, obtener recompensas y, a la vez, ajustarse al cumplimiento de normas. Así mismo, se evidenció que la educación orienta hacia las competencias emocionales, contribuye a fortalecer los niveles de socialización de los niños y niñas, quienes desarrollan además habilidades como la empatía y el afrontamiento ante desafíos.
Experiencias de feminidad y autosatisfaccion en mujeres universitarias
Authors: Ramos Brenda , Bolaños Ceballos Fernando , Cazares Itzia
Published: June 2022

Las ideas estereotipadas de género en la cultura y contexto específicos de las personas determinan en gran parte el desarrollo humano y las experiencias de feminidad y masculinidad. Se realizó un estudio descriptivo, no experimental, transversal y con metodología cualitativa, con el objetivo de conocer las experiencias de mujeres universitarias mexicanas en torno a la auto-satisfacción con su experiencia cotidiana de feminidad. Empleando las técnicas de grupo focal y análisis de contenido, se analizó el discurso grupal de 17 mujeres. Se identificaron elementos tradicionales y otros novedosos de género en la subjetividad y prácticas de las participantes. Entre otros hallazgos, se reportó que el ideal de feminidad de las participantes radica en ser tratadas de forma equitativa y sin distinciones sexistas; el contexto familiar y comunitario, así como el acoso sexual en espacios públicos, destacaron en las valoraciones sobre estas experiencias.
Quantum Biophysics of the Atmosphere: Asymmetric Wavelets of the Average Annual Air Temperature of Irkutsk for 1820-2019
Authors: Matveevich Mazurkin Peter
Published: June 2022

The regularities of the dynamics of the average annual temperature of Irkutsk from 1820 to 2019 were revealed. It is proposed to use the sum of temperatures. However, this indicator requires the continuity of the dynamic series, so for Irkutsk the sum of temperatures could be accepted only from 1873. The first three terms of the general wavelet model gave a very high correlation coefficient of 0.9996. The second indicator is a moving average, calculated as the ratio of the sum of temperatures to the current time. Here the first three wavelets gave a correlation coefficient of 0.9962. In the dynamics of the average annual temperature from 1820 to 2019, 86 wavelets were obtained, of which 47 affect the future. The temperature has a high quantum certainty, and the change in the average annual temperature of Irkutsk is obtained up to a measurement error of 0.05 °C, and the identification process occurs as a full wavelet analysis. The basis of the forecast in 200 years makes it possible to replace the non-linear two-term trend with an oscillatory perturbation. With an increase in the number of terms in the model, the ordinate of the average annual temperature increases: For three terms, the temperature interval is from –2.95 °C to 2.61 °C; for 12 members from –4.06 °C to 4.02 °C; for the forecast for 47 members for 2020- 2220, from –4.62 °C to 4.40 °C.
Evaluation of sleep quality and prevalence of depression in pregnant women
Authors: Hima Bindu Nallapu  , Satish Chinnala
Published: June 2022

Objective: Poor sleep quality and depression during the pregnancy period leads to maternal complications and adverse fetal effects. There are various etiological factors that may cause sleep deprivation and depression during gestation. Our study aims to evaluate sleep quality and prevalence of depression in pregnant women. Methods: This is a Prospective Observational study carried out in pregnant women. Sleep Quality. PSQI and BDI scales were used to assess sleep and depression respectively. Results: In our study there is significant decrease in sleep quality and higher prevalence of depression in pregnancy. A significant correlation existed between sleep deprivation and depression with Trimesters of Pregnancy. Conclusion: There is a need for development of effective methods of detecting and management of depression and sleep quality during pregnancy individualized to each patient.
Artificial intelligence for radiomics; diagnostic biomarkers for neuro-oncology
Authors: Farzan Vahedifard  , Sara Hassani  , Ali Afrasiabi  , Armin Modarresi Esfe
Published: June 2022

Recent advances in medical image analysis have been made to improve our understanding of how disease develops, behaves, and responds to treatment. Magnetic resonance imaging (MRI) and positron emission tomography (PET) advanced imaging strategies provide structural and functional phenotypic biomarkers that correlate with key disease processes. Through radiomics and radiogenomics, ML-medical imaging has opened up new perspectives in high-grade glioma diagnosis. As a result, non-invasive and in vivo biomarkers for patient survival, tumor recurrence, and genomics are identified. Tumor genomic imaging signatures can help identify patients who benefit from targeted therapies. Molecular characterization of gliomas and prediction of their evolution would allow treatment optimization. Radiomics-based biomarkers allow for a more in-depth analysis of pathophysiologic processes and insights into diagnosing better, classifying, stratifying, and prognosticating brain tumors and assessing their response to therapy. Radiomics is a new data-driven approach that can help answer clinical questions like diagnosis, prognosis, and treatment response. With encouraging outcomes in brain tumor patients, radiomics and deep learning are still not widely used in clinical practice, requiring more extensive and practical clinical studies.
Pengembangan PENGEMBANGAN MEDIA BUKU PINTAR UNTUK KEMAMPUAN SOSIAL EMOSIONAL DENGAN KEGIATAN BERCERITA DI KELOMPOK A TKM NU 295 ROUDLOTUN NAFILAH GRIYA PEGANDEN ASRI
Authors: Musayyachah Musayyachah
Published: June 2022

Penelitian ini bertujuan untuk mengembangkan dan mengetahui tingkat kelayakan media pembelajaran berupa Buku Pintar untuk perkembangan keterampilan sosial emosional anak Kelompok A. Penelitian ini merupakan Penelitian dan Pengembangan (Research and Development) 6 tahapanm, yaitu : 1) mengobservasi potensi dan masalah, 2) pengumpulan data, 3) desain produk, 4) validasi desain, 5) revisi produk, dan 6) ujicoba produk. Penelitian ini menggunakan angket untuk mengevaluasi kualitas media pembelajaran, respon anak, orangtua, guru dan kepala sekolah.validasi media pembelajaran dilakukan oleh dosen Jurusan PIAUD Universitas Muhammadiyah Gresik, dan diujicobakan pada anak Kelompok A di TKM NU 295 Roudlotun Nafilah Griya Peganden Asri. Hasil penelitian ini adalah produk media pembelajaran Buku Pintar untuk perkembangan sosial emosional anak kelompok A. Penilaian aspek kelayakan media pembelajaran memperoleh presentase sebesar 68,18% dengan kategori “Baik” sehingga layak di ujicobakan dan untuk respon anak peneliti mendapatkan skor 58 dan kelayakan produk sebesar 80,55% dengan kesimpulan hasil produk termasuk dalam kategori “Sangat Baik” atau media “buku pintar” layak digunakan sebagai media perkembangan sosial emosional anak di sekolah.

Kata kunci : media pembelajaran, buku pintar, bercerita, sosial emosional, Metode Research and Development
Performance Evaluation of Public Service Mall (Mall Pelayanan Publik) in Indonesia using the Balanced Scorecard
Authors: Rahayu Amy Yayuk Sri , Puji Rahmayanti Krisna , Mahendra Wahyu , Amania Afra Syifa
Published: June 2022

The provision of public services in various regions in Indonesia began to be integrated into the public service mall (PSM) or Mall Pelayanan Publik (MPP), an expansion of the Office of Investment and One-Stop Integrated Services (DPMPTSP). The evaluation of public services showed a significant increase in the public service achievement index (Kemenpan RB, 2021). However, this evaluation was based on the perspective of the public as service users, whilst other crucial perspectives, namely internal processes, employee learning, and growth, and finance, are yet to be considered. For the comprehensive performance evaluation, a Balanced Scorecard (BSC) was employed in this study. This study aims to measure the performances of 11 MPP using the scorecard, in which the scores can be used as a basis for improvement and reinforcement of MPP in the future. By using a mix method approach, the results found that two aspects, finance and employee learning and growth, experience the lowest score. Meanwhile, two other dimensions (service quality and internal processes) obtained optimum results. These findings bring a main recommendation to revisit the nomenclature of MPP: expected to adopt data and authority integration, improve management clarity, and enhance organization capacity and capability.
La traduzione dei classici per l'infanzia in una prospettiva di genere
Authors: Illuminati Valeria
Published: June 2022

Gli approcci di genere alla traduzione dei testi destinati a giovani lettrici e lettori rappresentano un ambito di ricerca recente, emerso solo all’inizio degli anni Duemila. Il volume si inserisce in tale contesto di studio indagando i punti di contatto tra la traduzione della letteratura per l’infanzia e la traduzione in prospettiva di genere, a partire da un corpus costituito da classici per l’infanzia francesi e inglesi tradotti in italiano. Grazie alla dimensione diacronica dischiusa dalla ritraduzione, l’analisi comparativa esplora la possibilità di tradurre prestando attenzione alle problematiche di genere, rintracciando le strategie linguistiche, testuali e paratestuali messe in atto nel processo traduttivo in relazione a tali aspetti. Combinando analisi quantitativa e qualitativa, la ricerca restituisce così la complessità dei legami tra genere e traduzione letteraria per l’infanzia. Valeria Illuminati insegna Lingua francese presso il Dipartimento di Interpretazione e Traduzione dell’Università di Bologna, Campus di Forlì. Membro del Centro MeTRa e dei progetti europei GBOOK, volti a promuovere una letteratura per ragazze e ragazzi “positiva” dal punto di vista di genere, è autrice di pubblicazioni sulla traduzione in prospettiva di genere e sull’audiodescrizione.
Features of operation of ship electrical power systems with electrical propulsion systems
Authors: Savenko A. E. , Savenko P. S.
Published: June 2022

THE PURPOSE. Consider the issue of the presence of distortions in the form of sinusoidal voltage and current in autonomous electrical power systems with electrical propulsion systems, built on the principle of the unified electric power system. Compare the results of the study of voltage distortion for electrical power systems with electrical propulsion systems of various structures and give recommendations for their application.

METHODS. For research, unified electric power systems with DC electrical propulsion systems on the Yeysk ferry and alternating current on the asymmetric icebreaker Baltika are considered. The possibilities of programming with frequency control of modern drives of rudder propellers with AC motors are analyzed.

RESULTS. Oscillograms of voltages and currents of generators were obtained using thyristor converters and inverters to control electrical propulsion systems in various modes. Significant ripples and distortions of the sinusoidal voltage and generator currents were noted when thyristor converters are used to power DC propulsion electric motors. Also, small deviations from the sinusoidal form of the ship's network voltage were recorded when inverters were used to control AC propulsion motors as part of rudder propellers.

CONCLUSION. The issue of ensuring the quality of electricity produced in autonomous electrical power systems of sea vessels is of great relevance and importance. To ensure the best results, it is advisable to use azimuthing podded drive with AC electric motors, the rotation speed of which is implemented by inverter frequency converters with a DC link.
Kemampuan Pemecahan Masalah Matematis pada Pembelajaran Berbasis Etnomatematika
Authors: Masruroh Masruroh , Zaenuri Zaenuri , Walid Walid , Waluya S.B.
Published: June 2022

Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan kemampuan pemecahan masalah matematis pada pembelajaran bernuansa etnomatematika. Metode yang digunakan dalam penelitian adalah systematic literature review. Hasil seleksi artikel dari 20 artikel yang terbit dari tahun 2017-2021 didapatkan 9 artikel nasional dan internasional bereputasi tentang kemampuan pemecahan masalah matematis dalam pembelajaran bernuansa etnomatematika. Hasil identifikasi dan analisis artikel ditemukan bahwa pembelajaran matematika bernuansa etnomatematika menjadi salah satu alternatif pembelajaran matematika untuk meningkatkan kemampuan pemecahan masalah matematis siswa. Pembelajaran bernuansa etnomatematika memberikan kesempatan kepada siswa untuk berdiskusi tentang materi yang dipelajari kemudian dikaitkan dengan pengalaman kebiasaan budaya siswa yang pernah dialami siswa sehingga siswa dapat memahami, mengolah, dan menggunakan ide-ide dan konsep matematika terkait pengalaman siswa untuk memecahkan permasalahan matematika yang berkaitan dengan aktivitas sehari-hari siswa secara inovatif dan mandiri. Penggunaan model pembelajaran dalam pembelajaran matematika bernuansa etnomatematika dapat disesuaikan dengan materi, permasalahan serta situasi tempat penelitian.
Prenatally diagnosed fetal heart rhythm abnormalities—incidence, diagnosis and outcome
Authors: Stamenković Jelena , Parezanović Vojislav , Kontić-Vučinić Olivera , Stefanović Ivan , Trkulja Maja , Jovanović Ida , Ljubić Aleksandar , Srbinović Milena
Published: June 2022

Backrounds: Fetal arrhythmias represent a significant cause of fetal morbidity and mortality and occur in approximately 1–3% of pregnancies. The unknown fetal arrhythmias are the cause of intrauterine fetal demise in as many as 3–10% of cases, as well as the cause of unexplained fetal hydrops or premature births. Methods: A fetal echocardiography test makes it possible to notice structural heart defects at very early stages of pregnancy. The ultrasound heart rate monitoring also involves the use of specific Doppler methods. Heart rhythm disorders may occur in the form of tachycardia (sinus tachycardia (ST), supraventricular tachycardia (SVT) and atrial flutter (AF)) or in the form of bradycardia (sinus bradycardia (SB), atrial bigeminy (AB) and complete AV block). The most frequently diagnosed fetal heart rhythm disorders are isolated extrasystoles with no clinical significance. Results: In this study, we have examined 7863 fetuses (182 were multiple gestations). Out of the total number of examined patients, 572 fetuses (7.23%) had pathological heart features, while 127 (1.61%) had some form of rhythm disorder. Conclusions: The ability to recognize the heart rhythm disorder and commence the treatment in a timely manner increases the treatment success rate.
Herlyn-Werner-Wunderlich syndrome with double hematocolpos in one side hemivagina
Authors: Kim You Jin , Yang Jung Bo , Jung Ye Won , Song Soo Youn , Lee Geon Woo , Yoo Heon Jong
Published: June 2022

Background: Herlyn-Werner-Wunderlich syndrome (HWWS) is an extremely rare Mullerian anomaly consisting of uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis. Although few HWWS cases had been reported in the gynecological literature, most of the reported cases were combined with single hematocolpos. Case: We report here on a case of HWWS with double hematocolpos on one side of a hemivagina combined with ipsilateral renal agenesis. This is the first report of HWWS with double hematocolpos on one side of a hemivagina that was successfully treated with the resection of the vaginal septum. Conclusion: It is important to understand the pathogenesis and clinical features of these anomalies for diagnosis.
An Inverse QSAR Method Based on Linear Regression and Integer Programming
Authors: Zhu Jianshen , Azam Naveed Ahmed , Haraguchi Kazuya , Zhao Liang , Nagamochi Hiroshi , Akutsu Tatsuya
Published: June 2022

Background: Drug design is one of the important applications of biological science. Extensive studies have been done on computer-aided drug design based on inverse quantitative structure activity relationship (inverse QSAR), which is to infer chemical compounds from given chemical activities and constraints. However, exact or optimal solutions are not guaranteed in most of the existing methods. Method: Recently a novel framework based on artificial neural networks (ANNs) and mixed integer linear programming (MILP) has been proposed for designing chemical structures. This framework consists of two phases: an ANN is used to construct a prediction function, and then an MILP formulated on the trained ANN and a graph search algorithm are used to infer desired chemical structures. In this paper, we use linear regression instead of ANNs to construct a prediction function. For this, we derive a novel MILP formulation that simulates the computation process of a prediction function by linear regression. Results: For the first phase, we performed computational experiments using 18 chemical properties, and the proposed method achieved good prediction accuracy for a relatively large number of properties, in comparison with ANNs in our previous work. For the second phase, we performed computational experiments on five chemical properties, and the method could infer chemical structures with around up to 50 non-hydrogen atoms. Conclusions: Combination of linear regression and integer programming is a potentially useful approach to computational molecular design.
Effects of Spermidine on Cell Proliferation, Migration, and Inflammatory Response in Porcine Enterocytes
Authors: Wei Zi-xi , Cai Long , Zhao Xue-mei , Jiang Xian-ren , Li Xi-long
Published: June 2022

Background: Polyamines have been demonstrated to be beneficial to porcine intestinal development. Our previous study showed that putrescine mitigates intestinal atrophy in weanling piglets and suppresses inflammatory response in porcine intestinal epithelial cells, it is still unknown the role of spermidine in mediating putrescine function. Objective: The current study aimed to investigate the effect of spermidine on the proliferation, migration, and inflammatory response in porcine intestinal epithelial cells (IPEC-J2 cell line). Methods: The effects of spermidine on proliferation and migration of IPEC-J2 cells were measured. Difluoromethyl ornithine (DFMO) and diethylglyoxal bis (guanylhydrazone) (DEGBG) were used to block the production of putrescine and spermidine, respectively. A cell inflammation model was established with lipopolysaccharides (LPS) stimulation. Gene expression and protein abundance were determined by real-time quantitative PCR and western blotting, respectively. Result: Spermidine significantly enhanced cell proliferation in DFMO (or/and) DEGBG treated IPEC-J2 cells (p < 0.05). Pretreatment with putrescine restored cell growth inhibited by DFMO but did not prevent the decrease in cell proliferation caused by DEGBG (p > 0.05). Similarly, spermidine but not putrescine significantly elevated the rate of migration in DEGBG treated IPEC-J2 cells (p < 0.05). Spermidine deprivation by DEGBG dramatically enhanced mRNA abundance of pro-inflammatory cytokines IL-8, IL-6, and TNF-α (p < 0.05), and the addition of spermidine attenuated excessive expression of those inflammatory pro-inflammatory cytokines, moreover, spermidine but not putrescine suppressed the phosphorylation of NF-κB induced by DEGBG. Spermidine supplementation also significantly suppressed LPS-induced the expression of TNF-α. Conclusions: The present study highlights a novel insight that putrescine may be converted into spermidine to modulate cell proliferation, migration, and inflammatory response on porcine enterocytes.
SENDİKALAR VE İŞ GÜVENCESİ: GÜVENCESİZ SENDİKACILIĞA DOĞRU MU?
Authors: AYDIN Aykut
Published: June 2022

Üyelerinin ekonomik ve sosyal çıkarlarını koruma görevi olan sendikalar, bu görevi yerine getirirken küresel etkilerin yol açtığı zorlu bir süreçten geçmektedir. Yoğun rekabet, yeni ekonomik şartların istihdam piyasalarına yansıyan yönleriyle esnek üretim ve esnek çalışma biçimlerinin yaygınlaşması; sendikaların etki alanlarını daraltan ve sendikal yoğunlukta azalmaya yol açan önemli küresel zorluklardır. Bu zorluklar ayrıca, sendikaların ana fonksiyonlarından biri olan iş güvencesi sağlama fonksiyonu ile ilgili tartışmaların gün yüzüne çıkmasına neden olmuştur. Sendikalar, esnek ve giderek güvencesiz hale gelen bir istihdam piyasası düzeni içerisinde konumlanmaktadır. İş güvencesi sağlama fonksiyonları zayıflayan sendikalar, güvencesiz sendikacılığa doğru bir süreç içerisine girmiş görünmektedir. Güvencesiz sendikacılık hareketinin, zayıflayan iş güvenceleri ile sendikalı çalışanlar ya da yeni sendikalaşanlar için tavizler mi vereceği ya da imtiyazlar mı edineceği önümüzde duran sorulardır. Şu ana kadar yapılan araştırmalar, sendikaların iş güvencesi fonksiyonunu ne kadar yerine getirebildiği, sendikaların bu fonksiyonuna ilişkin çalışanların algıları, kamu-özel sektör sendikalarının iş güvencesi ile ilgili uygulama farklılıkların olup olmadığı gibi birtakım sorulara yanıt bulmaya çalışmıştır. Çalışmada, iş güvencesi ve iş güvencesizliği kavramlarına, sendikalar için iş güvencesinin önemine, konu ile ilgili araştırmalara, bulgulara ve güvencesiz sendikacılık hareketine değinilmiştir. Çalışma, sendikaların esnek istihdam piyasaları ve şartları karşısında iş güvencesi konusunda yaşayacağı muhtemel sorunlara ışık tutmayı amaçlamaktadır.
Kecenderungan Global Dalam Proses Pembelajaran Pendidikan Pancasila Kewarganegaraan Di Sekolah
Authors: Putri Nabila Ananda Gunawan
Published: June 2022

Kecenderungan global dalam pendidikanDancasia dan kewarganegaraan untuk demokrasi yang secara luar biasa berpotensimempengaruhi pendidikan pancasila dan kewarganegaraan pada negara-negara yangmenganut faham demokrasi konstitusional.kecenderungan global itu adalah komponen-komponen yang saling berinterelasi,pengajarankonsep-konsep inti secara sistematik analisis terhadap studi kasus,keterampilan-keterampilan pembuatankeputusan, analisis komparatif, keterampilan partisipatoris dan kebajikan Ward heyardmelalui kegiatan-kegitan belajar,penggunaan buku sumber, pengetahuan, keterampilan dankebajikan kebajikan warga negara, dan menghubungkan antara isi dan prosesdalam belajar mengajar pengetahuan, keterampilan dan kebajikan-kebajikan warga negara.Berdasarkan kecenderungan global, kajian tentang kecenderungan global dalam pendidikanpancasila dan kewarganegaraan cukup berpengaruh terhadap perkembanganpendidikan pancasila dan Kewarganeydrdanpada tingkat persekolahan di Indonesia.
Konsep Keselamatan Menurut Pandangan Paulus
Authors: Tumanang Morde
Published: June 2022

AbstractBasically, the purpose of writing this paper is to find an understanding of the concept of salvation. A work done by Jesus for all believers is a very powerful thing. This salvation is carried out by Jesus himself, and can be obtained through believing in Jesus Christ the savior. The work of salvation is a solution to overcome sin. Faith and works result from many people not understanding the meaning of grace. In the view of many, Faith must be parallel to deeds. In this paper, the author will try to show how in the Word of God one must really understand Faith as an action that has occurred in life. In the relationship of human life, without faith, humans will not have salvation. Humans accept that salvation only comes from God, and how do humans work that salvation seriously. The tenacity of principles possessed by everyone seems to shift over time. Thus, the writer wants to take a qualitative approach to solve the problems that arise regarding God's saving work.AbstrakPada dasarnya, tujuan penulisan karya tulis ini adalah untuk menemukan sebuah pengertian mengenai konsep dari keselamatan. Sebuah karya yang dilakukan oleh Yesus bagi semua orang percaya merupakan sebuah hal yang sangat dahsyat. Penyelamatan itu dilakukan oleh Yesus sendiri, dan dapat diperoleh melalui percaya kepada Yesus Kristus Sang penyelamat itu. Karya penyelamatan itu merupakan sebuah solusi untuk melewati dosa. Iman dan perbuatan diakibatkan pada ketidakmengertian banyak orang akan arti dari kasih karunia itu. Dalam pandangan yang sekian banyak, Iman itu harus sejajar dengan perbuatan. Dalam tulisan ini, penulis akan berusaha menunjukkan bagaimana dalam Firman Tuhan harus benar-benar memahami Iman sebagai perbuatan yang telah terjadi dalam kehidupan. Dalam relasi kehidupan manusia, tanpa Iman manusia tidak akan mempunyai keselamatan. Manusia menerima keselamatan itu hanya berasal dari Allah, dan bagaimana manusia mengerjakan keselamatan itu dengan sungguh-sungguh. Keteguhan prinsip yang dimiliki oleh setiap orang seiring berjalannya waktu. Demikianlah penulis hendak melakukan pendekatan kualitatif untuk memecahkan masalah yang didapat seputar karya penyelamatan Allah.
Kebijakan fiskal perspektif Islam
Authors: amaliyah zahra
Published: June 2022

Ditinjau dari etimologi, kebijakan fiskal berasal dari dua kata, yaitu kebijakan dan fiskal. Kebijakan (policy) memiliki arti yang bermacam-macam, Harold D. Laswell dan Abraham Kaplan memberi arti kebijakan sebagai suatu program pencapaian tujuan, nilai-nilai dan praktik-praktik yang terarah. Kebijakan fiskal adalah kebijakan ekonomi yang digunakan pemerintah untuk mengelola perekonomian.
PEMIKIRAN TAQIYUDDIN AN-NABHANI TENTANG KEPEMILIKANDALAM SISTEM EKONOMI ISLAM
Authors: Hasna salsabila , harefa Primoadin
Published: June 2022

Taqiyuddin an-Nabhani adalah seorang ulama, politikus dan tokoh berpengaruh yang berasal dari Palestina. Aktivitas politik merupakan aspek yang menonjol dalam kehidupannya. Hal ini menampakkan kecermatan dalam karya- karyanya. Ia juga banyak menelaah peristiwa-peristiwa politik, lalu mendalaminya dengan amat cermat, disertai pemahaman sempurna terhadap situasi-situasi politik dan ide-ide politik yang ada. Ia termasuk salah seorang pemikirdan politikus terulung pada abad 20. Ia mempunyai gagasan tentang Ekonomi Islam, beliau mengungkapkan bagaimana prinsip dasar ekonomi islam. Prinsip-prinsip dasar sistem ekonomi islam menurut Taqiyuddin an-Nabhani dijalankan atas asas kepemilikan, pemanfaatan pemilikan, dan konsep distribusi kekayaan yang hal ini akan sangat bertentangan apabila dihadapkan dengan kapitalisme dan sosialisme. Dalam konsep kepemilikan kapitalisme berpendapat bahwa kepemilikan pribadi sebagai prinsip dasarnya, sedangkan sosialisme mengakui kepemilikan kolektif sebagai prinsipnya. Lain halnya dalam sistem Islam mengakui tiga jenis kepemilikan (kepemilikan individu, kepemilikan umum, kepemilikan negara). Ia memahami Bahwa Islam bukan sebagai agama saja, tetapi sebuah ideologi, sistem yang termasuk didalamnya tentang negara. Islam sebagai sebuah ideologi mempunyai sistem kehidupan yang menyeluruh dalam semua aspek kehidupan, termasuk didalamnya sistem ekonomi. Sebagai sebuah sistem menuntut untuk diterapkan secara totalitas dalam kehidupan.
instrumen dan komponen kebijakan fiskal islami
Authors: amaliyah zahra
Published: June 2022

Dalam Islam, kebijakan fiskal merupakan salah satu perangkat untuk mencapai tujuan syariah yang menurut imam al-Ghazali termasuk peningkatan kesejahteraan dengan tetap menjaga keimanan, kehidupan, intelektualitas, kekayaan dan kepemilikan. Pada dasarnya kebijakan fiskal telah lama dikenal dalam teori ekonomi Islam, yaitu sejak zaman Rasulullah dan Khulafaur Rasyidin, dan kemudian dikembangkan oleh para ulama. Ibnu Khaldun (1404) mengajukan obat untuk resesi berupa mengecilkan pajak dan meningkatkan pengeluaran pemerintah, pemerintah adalah pasar terbesar, ibu dari semua pasar, dalam hal besarnya pendapatan dan penerimaannya.
EEG ERP Preregistration Template
Authors: Govaart Gisela Hanna , Schettino Antonio , Helbling Saskia , Mehler David Marc Anton , Ngiam William Xiang Quan , Moreau David , Chiossi Francesco , Zanesco Anthony Paul , Yang Yu-Fang , Gau Remi , Bartlett James Edward , García Alanis José C. , Gutsell Jennifer Nadine , Çetinçelik Melis , Pavlov Yuri G. , Šoškić Anđela , Ehinger Benedikt Valerian , Mouseli Pedram , Algermissen Johannes , Topor Marta , Pérez-Navarro Jose , Häberle Greta , Schreiner Melanie Steffi , Rothmaler Katrin , Niso Guiomar , Paul Mariella
Published: June 2022

This preregistration template guides researchers who wish to preregister their EEG projects, more specifically studies investigating event-related potentials (ERPs) in the sensor space.
Advances in seismic imaging of magma and crystal mush
Authors: Paulatto Michele , Hooft Emilie , Chrapkiewicz Kajetan , Heath Benjamin , Toomey Douglas , Morgan Joanna
Published: June 2022

Seismic imaging methods have provided detailed three-dimensional constraints on the physical properties of magmatic systems leading to invaluable insight into the storage, differentiation and dynamics of magma. These constraints have been crucial to the development of our modern understanding of magmatic systems. However, there are still outstanding knowledge gaps resulting from the challenges inherent in seismic imaging of volcanoes. These challenges stem from the complex physics of wave propagation across highly heterogeneous low-velocity anomalies associated with magma reservoirs. Ray-based seismic imaging methods such as travel-time and surface-wave tomography lead to under-recovery of such velocity anomalies and to under-estimation of melt fractions. This review aims to help the volcanologist to fully utilize the insights gained from seismic imaging and account for the resolution limits. We summarize the advantages and limitations of the most common imaging methods and propose best practices for their implementation and the quantitative interpretation of low-velocity anomalies. We constructed and analysed a database of 277 seismic imaging studies at 78 arc, hotspot and continental rift volcanoes. Each study is accompanied by information about the seismic source, part of the wavefield used, imaging method, any detected low- velocity zones, and estimated melt fraction. Thirty nine studies attempted to estimate melt fractions at 22 different volcanoes. Only five studies have found evidence of melt storage at melt fractions above the critical porosity that separates crystal mush from mobile magma. The median reported melt fraction is 13% suggesting that magma storage is dominated by low-melt fraction crystal mush. However, due to the limits of seismic resolution, the seismological evidence does not rule out the presence of small (<10 km^3) and medium-sized (<100 km^3) high- melt fraction magma chambers at many of the studied volcanoes. The combination of multiple tomographic imaging methods and the wider adoption of methods that use more of the seismic wavefield than the first arriving travel-times, promise to overcome some of the limitations of seismic tomography and provide more reliable constraints on melt fractions. Wider adoption of these new methods and advances in data collection are needed to enable a revolution in imaging magma reservoirs
Variational and numerical modelling strategies for cost-effective simulations of driven free-surface waves
Authors: Gidel Floriane , Lu Yang , Bokhove Onno , Kelmanson Mark
Published: June 2022

A new, cost-effective and widely applicable tool is developed for simulating three-dimensional (3D) water-wave motion in the context of the maritime-engineering sector, with specific focus on the formation and analysis of extreme waves generated within in-house experimental wave tanks. The resulting ``numerical wave tank'' is able to emulate realistic sea states in which complex wave-wave or wave-beach interactions occur. After first transforming the time-dependent free surface and oscillatory wavemaker into a static rectilinear domain with fixed boundaries, a variational approach is used to derive weak formulations that lead to a non-autonomous space-discrete Hamiltonian system to which robust (stable and mass-conserving) temporal integrators are applied. Specifically, first-order symplectic-Euler and second-order Stormer-Verlet schemes are implemented in the finite-element environment ``Firedrake'', and convincing validation of the new tool is demonstrated via a comparison of its numerical results with data post-processed from real wave-tank experiments at the Maritime Research Institute Netherlands (MARIN). Current and future extensions to industrial applications are discussed.
Changes in Preferences Reported After Choices Are Informative, Not Merely Statistical Artifacts
Authors: Lee Douglas G. , Pezzulo Giovanni
Published: June 2022

Decades of research has shown that people rate things more favorably if they have recently chosen them and less favorably if they have recently rejected them. This spreading apart of the ratings of the alternative options (“spreading of alternatives” or SoA) has been described as choice-induced preference change, where the act of choosing causes evaluations to systematically differ after choices relative to before. An important study pointed out that SoA can be detected in the data even without it being caused by a choice, as the result of a statistical artifact. This potential alternative source of SoA has encumbered researchers who investigate the phenomenon, impeding progress in the field field – and a deeper investigation of the cognitive mechanisms behind SoA. Here, we present a novel approach to control for the statistical artifact explanation through the use of regression analysis supported by computational simulations. Our approach provides a logical and computational manner of distinguishing the possible sources of SoA in experimental data that is quick and easy to implement. We demonstrate our approach by comparing theoretical predictions of the statistical artifact and other possible explanations of SoA with empirical data, and show that the statistical artifact alone cannot account for the data.
A Network Analysis of the PART-O at 1 and 2 Years after TBI: A Veterans Affairs Model Systems Study
Authors: West Samuel James
Published: June 2022

The construct of participation after traumatic brain injury (TBI) can be difficult to operationalize. Psychometric network analysis offers an empirical approach to visualizing and quantifying the associations between activities that comprise participation, elucidating the relations among the construct’s components without assuming the presence of a latent common cause and generating a model to inform future measurement methods. The current research applied psychometric network analysis to the Participation Assessment with Recombined Tools- Objective (PART-O) within a sample of Service Members and Veterans (SM/Vs) with a history of TBI at 1- and 2-years (T1 and T2) post-injury.Participants (N = 663) were SM/Vs with a history of TBI who completed comprehensive inpatient rehabilitation services at a VA Polytrauma Rehabilitation Center (PRC). Setting: Five VA PRCs. Design: Cross-sectional, retrospective analysis of data from the Veterans Affairs (VA) TBI Model Systems study. Main Measures: Participation Assessment with Recombined Tools-Objective (PART-O). Network analysis demonstrated that the PART-O structure was generally consistent over time, but some differences emerged. The greatest difference observed was the association between “spending time with friends” and “giving emotional support” to others. This association was more than twice as strong at T2 as at T1. The “out of the house” item was most central, as demonstrated by dense connections within its own subscale (Out and About) and items in other subscales (i.e., Social Relations and Productivity). When examining items connecting the three subscales, the items related to giving emotional support, Internet use, and getting out of the house emerged as the strongest connectors at T1, and Internet was the strongest connector at T2. Providing emotional support to others is associated with greater participation across multiple domains and is an important indicator of recovery. Being out and about, Internet use, and engagement in productive activities such as school and work shared strong associations with Social Relations. Network analysis permits visual conceptualization of the dynamic constructs that comprise participation, and has the potential to inform approaches to measurement and treatment.