bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Kemiringan Kolektor Menggunakan Adsorben Arang Aktif Terhadap Efisiensi Kolektor Surya Pada Proses Adsorpsi Mesin Pendingin
Authors: Amelia Septiyan Nur , Sudarsono Sudarsono , Hasbi Muhammad
Published: April 2022

Indonesia has abundant sources of solar energy with an average solar radiation intensity of about 4.8 kWh/m2 per day throughout Indonesia because it is located at the equator 6°N to 11°N and 9°E-141°E. That way the sun's energy that is not used up can be utilized. The purpose of this study is to determine the heat used by the collector for the desorption process and to determine the effect of variations in the angle of inclination of the collector on the efficiency of the collector. That way, one of them can be used for the water cooling process using a solar collector device on a solar heat adsorption cycle cooling machine The purpose of this study was to determine the heat used by the collector for the desorption process and to determine the effect of variations in the collector tilt angle on the efficiency of the collector. This research was conducted by varying the slope of the cooling machine collector with an adsorption cycle using solar energy. The test results show that the average theoretical useful heat at the collector (Qu) obtained by the 0° angle collector is 236,079 Watt, the 15° angle collector (from 08.00 – 15.30) is 131.683 Watt, and the 30° angle collector (from 08.00 – 16.00) is 179.638 Watt. on each test day. The average efficiency (η) from 08.00 – 15.30 (optimal measurement) obtained by the 0° angle collector is 51.296%, the 15° collector angle is 47.1%, and for the 30° angle collector the average efficiency is from 08.00 – 16.00 (optimal measurement) of 52.836%.Keywords: collector, adsorption, temperature.
Analisa Pengaruh Kuat Arus Terhadap Kekuatan Tarik Dan Bending Sambungan Las Kampuh V Menggunakan Las SMAW Dengan Elektroda E6013 Pada Pengelasan Baja Karbon Rendah
Authors: Ridwan Ridwan , Kadir Abd. , Aminur Aminur
Published: April 2022

Strong current in welding is something that has always been a problem in the welding process. High currents can cause penetration of the welded material, whereas low currents can cause shallow penetration. The purpose of the study was to determine the effect of current on the tensile and bending strength of V seam welded joints using SMAW welding with E6013 electrodes on low carbon steel welding. The research method used is to make a seam on a steel plate with an angle of 60 degrees and then weld it with a different current. The current used is 70, 90, 110 amperes with an electrode diameter of 2.6 mm. The samples that have been welded are then formed into tensile and bending test specimens. The results showed that the highest average tensile stress was 518.310 MPa at a welding current of 110 amperes. The highest average tensile strain is 34.00% at a welding current of 70 amperes. The highest average elastic modulus is 0.01864 GPa at a welding current of 110 amperes. For bending testing at 70 amperes, the fb1 specimen has cracks in the weld metal area with a crack length of 1.00 mm and the fb2 specimen has 0.50 mm cracks, while the 90 amperes fb1 specimen has 1.00 mm cracks, and fb2 specimens have 0.50mm crack. Current 110 amperes fb1 specimen has a crack of 4.70 mm, and fb2 specimen has a crack of 3.00 mm. From the results of the study, a good welding current for a plate with a thickness of 7.5 mm with an E6013 electrode with a diameter of 2.6 mm is at a current of 90 amperes.
Rancang Bangun Bilah Taperless Jenis Horizontal Axis Wind Turbin Untuk PLTB 500 Watt Dengan Airfoil NACA 6412 Menggunakan Software Qblade
Authors: Usman La Ode , Balaka Ridway , Imran Al Ichlas
Published: April 2022

Energy demand in Indonesia generally continues to increase due to population growth, one of the most widely used energies is wind energy. The research objectives are to determine the geometry of the blades, design and manufacture the blades suitable for use in moderate winds and to determine the power generated. The research started from determining the geometry of the blades for medium speed wind, then making the blades and then testing the blades. The geometry of the blades formed is tapertlles blades of the horizontal axis wind turbine type NACA 6412 airfaoil using Qblade software. The blade is designed with a blade radius of 0.774 m, the chord is 0.0999 m using mahogany wood material. The manufacturing method used is the manual method with the help of machine tools. The blades are tested for equilibrium, then mounted on the tower, 10 meters high to take the data. The test results show that the blades that have been made work well and produce an average power per second of 58.29 Watt, 90.82 Watt, and 102.00 Watt, for three days of testing.Keywords: Tuperless blades, airfoil naca 6412, qblade, horizontal axis wind turbines, mahogany wood.
Pengembangan Desain Kompor Gasifikasi Top Lith Up Draft (TLUD)
Authors: Syahrir Muhamad Ashar , Mangalla Lukas Kano , Imran Al Ichlas
Published: April 2022

The use of environmentally friendly stoves in the household sector can be an alternative to overcome the limited use of kerosene and the constrained supply of LPG. The purpose of the study was to develop a gasification stove design with the concept of Top Lith Up Draft on several variations of the column, namely without columns, column 2 holes and column 4 holes using cashew shell fuel which produces optimal gas fuel. The research method is the Top Lith Up Draft method, which is a gasification process semi-gasifier technology method that can produce fewer emissions that can harm human health. The results obtained indicate that the development of the TLUD gasification stove design from several variations of the column functions well. The gasification testing process carried out for the three variations of the column used resulted in good temperature values, namely for variations without a temperature column of 829 , column 2 holes of 935 , and column 4 holes of 934 . The best column variation is the 2 hole column with the highest temperature value of 935. Kata kunci: Gasification, TLUD, cashew shell,  efficiency.
Karakteristik Tegangan dan Regangan Tarik Pada Komposit CFRP Yang Berlubang
Authors: Ikhsan Muhammad , Sudarsono Sudarsono , Endriatno Nanang
Published: April 2022

In the industrial world, the development of material technology is growing rapidly. There is an increasing demand for materials with certain properties such as perforated composites. The consideration of perforated composites is an important parameter in the design of composite components. The purpose of this study was to determine the tensile stress and strain characteristics of hollow CFRP composites. The research method used is to analyze the tensile test using abaqus software, the tensile test analysis is carried out with 3 variations in the diameter of the hole (2 mm, 4 mm, and 6 mm). From the tensile test simulation results, it is found that the highest stress occurs in the 6 mm diameter composite with a maximum stress value of 180.4 N/mm², and the lowest stress occurs in the 2 mm diameter composite with a maximum stress value of 102.6 N/mm². The highest stress and strain that occurs in each specimen is located on the edge of the hole perpendicular to the direction of the force, the stress and strain increase based on the diameter of the hole in the composite, the larger the diameter in the composite, the greater the stress that occurs..Keywords: Tensile test, CFRP composite, abaqus software
Analisis Pengaruh Nilai Beban Unit Terhadap Efisiensi dan Heat Rate Turbin Pada Pltu Moramo
Authors: Ilham Muhammad , Salimin Salimin , Aksar Prinob
Published: April 2022

Moramo steam power plant is one of steam power plant in Indonesia that using coal as it fuels with capacity of 2x50 MW. Power produced by Moramo steam power plant is not always in constant condition because of fluctuation power in distribution grid with corresponding of power demand. One of the main indicators of steam turbine performance is the efficiency of steam turbine cycle and turbine heat rate. This research conducted to analyzes the effect of changes in power produced by Moramo steam power plant on the efficiency and turbine heat rate using a thermodynamic analysis approach and energy input-output methods. Analyzed data in this research is actual data during normal operation that taken from Distributed Control System (DCS). Results of this research indicated that the more the power produced by Moramo steam power plant the better of performance of its steam turbine. It is showed by the increase of average efficiency from 39.138% on 30 MW Net load to 39.369 % on 40 MW Net load, and increase to 39.976 % on 50 MW Net load. Furthermore, the increase of performance also showed by the decrease of its average turbine heat rate from 10137.79 kJ/kWh on 30 MW Net load to 9633.95 kJ/kWh on 40 MW Net load, and decrease to 9333.77 kJ/kWh on 50 MW Net load.Keywords: Load, efficiency, heat rate, steam power plant, steam turbine
Analisa Pengaruh Excess Air Terhadap Efisiensi Pembakaran Boiler Jenis Pulverizer Coal 230 T/H
Authors: Muholad Wildan , Hasbi Muhammad , Endriatno Nanang
Published: April 2022

To save on coal consumption in PLTU (Steam Power Plant), it is necessary to increase boiler efficiency. The factors that can affect boiler efficiency include: flue gas temperature, fuel specification, excess air, ambient temperature, radiation and convection losses. By changing the value of excess air in this case the percentage of oxygen (4% to 4.5%) will affect the efficiency of the boiler. Changing the value of excess air also results in a change in the electrical power used by the auxiliary system in the boiler. Calculation of boiler efficiency with the direct method by testing 2 times on each oxygen percentage value of 4% and 4.5. Efficiency increased 0.94%, from 80.76% to 81.7% in test 1 and increased 1.02%, from 90.81% to 91.83% in test II. The power usage increased by 27.959 Kw in the 1st test and increased to 26.663 Kw in the test II.Kata kunci: Boiler, efficiency, excess air, PLTU
Rancang Bangun Blade Turbin Angin Jenis Taper Untuk Pembangkit Listrik Tenaga Bayu Berskala Mikro
Authors: Kusmayanto La Ode Andi , Balaka Ridway , Imran Al Ichlas
Published: April 2022

The ultization of renewable energy in Indonesian kept on doing as the increase of amount in energy electricity demand as well as environmentally friendly energy requerements, efficient and sustainable. This study aims to learn about the blade’s geometric shapes designed and crafted, as well as the blade’s performance. The study has bee succesfully designed and crafted as soon as tested by the blade’s for a low-scale wind turbine. The design blade’s geometry is a type of taper, is the Horizontal of Axis Wind Turbine type with airfoil NACA 6412. The blade was design with Qblade software and built with a manual engine. The method of data collection was the blade installed on the tower at 30 meters for three days. The energy generated on a daily basis that is the first day, the energy average production is 45,80 watts with an average wind speed of 4,54 m/s, the second day of 55,11 watts with and average wind speed of 5,23 m/s, and the third day of 72,27 watts with an average wind speed 5,14 m/s.Keywords:Airfoil, blade, energy, wind turbine
Pengaruh Pemanasan Bahan Bakar Terhadap Laju Konsumsi Bahan Bakar Pada Sepeda Motor Sistem Karburator
Authors: Faradila Uswatun , Mangalla Lukas Kano , Sudia Budiman
Published: April 2022

The increasing human need for transportation requires maksimum engine performance and efficient fuel consumptiton on carburetor system motorcycles. In an effort to improve engine performance it is done various ways one of which is by preheating the fuel. This study aims to determine engine performance through preheating the fuel. This research was conducted on a motorcycle with a carburetor system by providing treatment without heating and by heating the fuel with a fuel preheat temperature of 60oC, 80oC, and 90oC at 2500 rpm engine speed and the fuel used is gasoline and pertamax. In this study, fuel consumption increased at 90oC by 0,38 (Kg/hour), at 80oC and 60oC decreased by 0,30 (Kg/hour) and 0,21 (Kg/hour). Specific fuel consumption at temperature 90oC  increased by 0,195 (Kg/kWh), at 80oC and 60oC decreased by 0,155 (Kg/kWh) and 0,106 (Kg/kWh) in gasoline, while in pertamax fuel, fuel consumption more efficient than gasoline, namely at a temperature of 90oC increased by 0,33 (Kg/hour), at 80oC and 60oC decreased by 0,22 (Kg/hour) and 0,19 (Kg/hour) while the specific fuel consumption at a temperature of 90oC increased by 0,170 (Kg/kWh), at 80oC and 60oC it decreased by 0,113 (Kg/kWh) and 0,095 (Kg/kWh).Kata kunci: Engine Performance, Preheating of fuel, Temperature Variations
Pemanfaatan Minyak Pirolisis Ban Bekas Menjadi Bahan Bakar Alternatif
Authors: Saputra Ade , Mangalla Lukas Kano , Salimin Salimin
Published: April 2022

Tire production in Indonesia is increasing continuously in line with the increasing automotive industry. Along with that, the waste of used tires that are not used in the environment is increasing. So we researched the use of used tire pyrolysis oil as an alternative fuel. The purpose of this study was to determine how to produce fuel oil through the pyrolysis process of used motorcycle tires and to determine the combustion characteristics of the pyrolysis results of motorcycle-used tires. The method used in this research is an experimental method using a pyrolysis tool and data collection is carried out directly with various temperature variations. The research was conducted at temperatures of 250oC, 300oC, and 350oC to produce 202 ml, 280 ml, and 219 ml of pyrolysis liquid, respectively. The pyrolysis oil combustion test produced shows that the burning of used tire pyrolysis oil takes longer than the burning of kerosene in the same volume. Keywords: Tires, pyrolysis, temperature
PENGUJIAN SISTEM TOREFAKSI KAYU JATI MENGGUNAKAN MICROWAVE
Authors: Sarifudin Sarifudin , Mangalla Lukas Kano , Barata La Ode Ahmad
Published: April 2022

Torrefaction is a heat treatment of raw biomass to obtain a fuel that is more stable, has a high energy density and higher brittleness and is easy to grind. The purpose of this study is to determine changes in physical properties, calorific value of water absorption resistance (hydrophobic) in teak wood after the torrefaction process in the microwave. The method used in this study is an experimental method using a microwave heater equipped with measuring instruments such as a digital thermometer, and digital scales. The biomass material used was finished wood cut with sample sizes of Model 1 (cube 3 x 3 cm), Model 2 (rectangular 7 x 3 x 3 cm), and Model 3 (cylindrical tube 7 x 3 cm). Each material was put in a microwave depth for torrefaction for 15, 25, 35 minutes. The results showed that the model 2 sample experienced the largest mass change of 80.95%, followed by model 3 with a mass change of 76.47% and Model 1 which experienced a mass change of 70%. The longer you experience electromagnetic wave radiation in the microwave, the greater the mass change and the lower the water absorption Keywords: Torrefaction, teak wood, microwave, calorific value, moisture content
Analisis Karakteristik Biomassa Cangkang Kelapa Dan Kulit Mete Melalui Proses Torefaksi
Authors: Nurudin La Ode , Mangalla Lukas Kano , Barata La Ode Ahmad
Published: April 2022

In the face of the depletion of fossil fuels, alternative fuels such as biomass are needed. However, biomass has a fairly low calorific value and several other disadvantages compared to petroleum. Therefore, a new breakthrough is needed to correct these weaknesses, one of which is the Torrefaction process. The purpose of this study was to determine the effect of torrefaction of coconut shell and cashew shell biomass on the physical and chemical properties of the material. This research was conducted using coconut shells and cashew shells. The results of this study indicate that the calorific value of coconut shells and cashew shells after torrefaction is 5115,297-5147,021 cal/gr. The water content in coconut shells is 2.718% and the value of water content in cashew shells is 2.397%, the ash content of coconut shells is 6.853% and the value of cashew shell ash content is 6.600%, the value of volatile levels of coconut shells is 14.885% and the value of volatile levels of cashew shells of 14.557% and the value of fixed carbon content of coconut shell is 75.574% and the value of fixed carbon content of cashew shell is 76.447%. Keywords : Biomass, coconut shell, cashewnut shell, torrefaction
Pengujian Eksperimental Perbandingan Konsumsi Bahan Bakar dan Emisi Gas Buang Dengan Beberapa Jenis Bahan Bakar Pada Sepeda Motor
Authors: Firsan Muhammad , Mangalla Lukas Kano , Hasanudin La
Published: April 2022

Air pollution is caused by the activities of motorized vehicles that emit exhaust gas emissions, including CO, CO2, HC, NOX, SOX, and particulates. The purpose of this study was to determine how the effect of fuel variations on the time of fuel consumption and exhaust emissions on motorcycles and to find out how the composition of mixing premium fuel with ethanol affects the time of fuel consumption and exhaust emissions. This study uses 4 types of fuel, namely premium, pertalite, E-5, and E-10 and tested using 3 variations of throttle openings. From the test results, it is found that the most fuel consumption is found in the wide throttle opening on premium fuel = 0.77 L/h. For the results of the lowest CO and HC exhaust emissions found in the wide throttle opening on the E-10 fuel where the emission value of CO = 1.98% and HC = 1425 ppm. So it can be concluded that in comparison with the time of fuel consumption, the higher the throttle opening, the faster the fuel consumption will be and for exhaust gas emissions, the higher the throttle opening, the lower the CO and HC emission values. Mixing premium fuel with ethanol can make the fuel consumption time slower than pure premium and can also reduce the content of CO and HC exhaust emissions.Key words: Fuel, Exhaust emissions, Fuel consumption
Desain Didaktis Pada Pelajaran al-Qur’an Hadist berdasarkan Analisis Hypothetical Learning Trajectory (HTL) terhadap Learning Obstacle Siswa Kelas XI
Authors: Yusnimar Yusnimar
Published: April 2022

This study based on the results of teachers discussions with preliminary data in the form of students’ cognitive test results and class observations. Cognitive tests of students were carried out aiming to see the problems that students often faced in learning Al-Qur’an Hadith. Problem that arise include; 1) students have difficulty memorizing verses and hadith, 2) difficult to master the interpretation and interpretation of the arguments provided in learning, 3) and it is difficult to practice the law of reading (tajwid). This is because learning Al-Qur’an Hadith is theoretical in nature so it necessary to prepare a learning design that is able to facilitate students learning and understanding the concept of Al-Qur’an Hadith. The learning design is based on a hypothetical learning trajectory (HTL) analysis of students cognitive abilities. This research is a descriptive analysis with a participant of 30 students of class XI. The result of study provide information for further research in the development of a didactical design that is hypthesized to improve students understanding in learning the Al-Qur’an and Hadith
Quando o paciente chora na consulta
Authors: Santos Marcia Cristina Lemos dos , Bastos Gabriela Sobrino Porto , Mantovani Aline Stefano , Santos Bianca Porto
Published: April 2022

Introdução: Nos atendimentos clínicos realizados na Atenção Primária, não é incomum que pacientes chorem durante a consulta. No entanto, os profissionais que atuam nesse âmbito podem não se sentir preparados para lidar com esse cenário, em virtude da falta de conhecimento de ferramentas para lidar com esse tipo de demanda. Objetivo: Este estudo propôs-se a elencar e categorizar técnicas para a abordagem ao paciente que chora, por meio de entrevistas realizadas com preceptores do Programa de Residência em Medicina de Família e Comunidade (MFC) da Secretaria Municipal de Saúde do Rio de Janeiro. Método: Foram realizadas entrevistas com 16 preceptores, que foram gravadas, transcritas e analisadas segundo os preceitos de Bardin. Resultados: Como resultado, obteve-se o compilado de 94 citações de técnicas não verbais e 27 de técnicas verbais, além dos modos de aprendizado delas, que ocorreram sobretudo por conhecimentos obtidos na Residência em MFC, na experiência prática e na leitura de temas correlatos, destacando-se referências sobre comunicação clínica. Ademais, foram categorizados os motivos para o choro dos pacientes, os sentimentos dos médicos, os objetivos das técnicas utilizadas e se se considera que elas auxiliam tanto médicos quanto pacientes nessa situação. Conclusões: Conclui-se que as técnicas empregadas pertencem ao conjunto de ferramentas de comunicação clínica baseadas em empatia e vínculo, e que o primeiro contato com elas ocorre geralmente na Residência em MFC; posteriormente elas são aprimoradas com a experiência clínica. Nesse contexto, destaca-se a importância da ênfase dada ao tema durante a especialização e da educação continuada em benefício do médico e do paciente.
Presenting Step-Ladder Expansive Cranioplasty as the Next Step After Decompressive Hemicraniectomy: It Is Different!
Authors: Kumar Sengupta Sudip
Published: April 2022

Context: Decompressive hemicraniectomy (DC) is the final surgical remedy for refractory raised intracranial pressure (ICP). Even with years of experience and profound refination of technique, the procedure has less rewarding results in traumatic brain injury (TBI). Besides, arrangements for bone flap preservation and the necessity of follow-up surgery in the form of cranioplasty bring in unavoidable monetary and logistic burdens to the patients. Step-ladder expansive cranioplasty was conceptualized as an alternative to achieve adequate intracranial volume expansion to help normalize ICP, with immediate reinstitution of the Monro-Kellie doctrine. It is also expected to prevent cerebral cortical pressure injury to the cortex underlying the craniectomy defect. The evolution of this concept, as worked out on different models, the surgical technique, and our experience with this technique are discussed in this article. Evidence Acquisition: Multiple research projects undertaken by our team to build up the concept and acquire data necessary to plan the surgical procedure have been published over last eight years. This review article attempts to evaluate the existing knowledge and our clinical experience so far. Results: Step-ladder expansive cranioplasty allows an assured centrifugal displacement of the inner table and underlying dural bag at craniotomy site by at least 9 mm, thereby achieving a minimum volume expansion of 120 cc for a circular craniectomy defect of 10cm dia. Both of these parameters can be increased as considered necessary by the surgeon. Conclusions: Step-ladder expansive cranioplasty offers an alternative that takes the centripetal pressure exerted by the combination of the tensile strength of the scalp and atmospheric pressure off the brain surface while achieving an assured augmentation of intracranial volume that can be optimized on a case-to-case basis, based on our future understanding of the subject. While it can be a single-stage surgery for those satisfied with the cosmesis, a revision cranioplasty (if required) will be easier, cheaper, and cosmetically superior to the presently popular cranioplasty techniques achieving cover over a craniotomy defect routinely done after DC.
Manual Leftward Displacement of the Uterus in the Prevention of Maternal Hypotension During Cesarean Section: A Randomized Comparative Study
Authors: Samimi Sadeh Saghar , Bastanhagh Ehsan , Yousefshahi Fardin , Smith Jane , Amirmohammadi Mina
Published: April 2022

Background: It is essential to maintain the hemodynamic state of mothers during delivery in cesarean section (CS). Research has shown that hypotension can be controlled by applying a 15° left lateral tilt. This can be achieved using an obstetric wedge or by tilting the operating table leftward. A systematic review of further research shows insufficient evidence to suggest whether it is effective or practical. Objectives: This study aims to evaluate the effectiveness of manual left tilting of the uterus on maintaining the hemodynamic status of mothers undergoing a CS delivery, where a spinal anesthetic has been given. Methods: Seventy women who were candidates for CS deliveries were randomly assigned into 2 groups as follows: group 1, the anaesthesiologist manually maneuvered the mother’s uterus to the left shortly after spinal anesthesia; group 2, the mothers’ uteruses were not displaced to the left. Sixty-seven of 70 participants completed the study. The hemodynamic status of the mother was reported before, during, and after surgery. The total doses of inotropic-vasopressors used to maintain hemodynamic stability were recorded. Results: The mother’s age, vital signs, and body mass index (BMI) before pregnancy and near term were not significantly different. Mothers maintained a significantly higher systolic blood pressure (SBP) when the uterus was displaced to the left (group 1). The mothers also required less ephedrine. Mothers in group 2 suffered a greater decrease in their SBP both after induction and before incision of the abdomen (group 2, P < 0.05). Conclusions: The manual tilting of the uterus to the left during CS is effective in maintaining blood pressure and decreases the need for vasopressors.
Discovery of a Potent Inhibitor to Overcome Carbapenem Resistance in Pseudomonas aeruginosa Strains via Inhibition of VIM-2 Metallo-β-lactamases
Authors: Moosavi Seyedeh Sara , Madani Mahboobeh , Mirzaie Sako , Hosseini Jazani Nima
Published: April 2022

Background: Mutations in bacteria frequently occur that display a crucial need for new antimicrobial agents. Metallo-β-lactamases (MBLs) are a growing threat to maintaining the effectiveness of beta-lactam antibiotics. Resistance to beta-lactam antibiotics is one of the most common types of antibiotic resistance, which causes the ineffectiveness of antibiotics. Objectives: This study aimed to identify a novel inhibitor using molecular dynamics simulations to inhibit VIM-2 Metallo-β-lactamases and overcome carbapenem resistance in Pseudomonas aeruginosa strains. Methods: Computational biology tools were employed for this study, including molecular dynamics, binding free energy, virtual screening, and docking. Natural compounds were taken from the ZINC databank and prepared. At the next stage, the prepared compounds were screened based on docking energy in the active site of VIM-2 MBL by Schrödinger (Maestro) software, and better compounds were selected. Captopril was chosen as a positive control inhibitor for VIM-2 MBLs. Ultimately, molecular dynamics simulations were performed using GROMACS software, and outputs were analyzed. Results: Maestro software's screening results showed that ZINC00517765 was the best inhibitor with -12.29 kcal mol-1 docking energy. The ADME investigations revealed that ZINC00517765 had an appropriate range of pharmacokinetics, lipophilicity, and drug-likeness features as an inhibitor of VIM-2 MBL. Molecular dynamics outcomes explicated that VIM-2 MBL in the presence of ZINC00517765 had better stability during simulation. The results of the MM-PBSA study illustrated that ZINC00517765 with -72.29 kJ mol-1 binding free energy was more potent than Captopril with -23.39 kJ mol-1. Conclusions: This study showed that VIM-2 MBL in the presence of ZINC00517765 has suitable stability during simulation. Also, more hydrogen bonds and stronger binding free energy than Captopril confirm that ZINC00517765 is a proper candidate for further studies and laboratory investigation.
Octreotide Efficacy and Safety in Pediatric Non-variceal Upper Gastrointestinal Bleeding: A Randomized Placebo-Controlled Clinical Trial
Authors: Mirrahimi Bahador , Rohani Pejman , Moradi Omid , Hemmati Azin
Published: April 2022

Background: Octreotide has been used to control bleeding episodes with variceal origin in the pediatric population. To date, there is no clear evidence of octreotide use for non-variceal bleeding in clinical trials. Objectives: We aimed to assess the octreotide efficacy as an add-on therapy to the conventional regimen of proton pump inhibitors for controlling upper non-variceal gastrointestinal (GI) bleeding in the pediatric population. Methods: This prospective randomized controlled clinical trial was performed on pediatric patients aged 1 - 15 years and diagnosed with acute non-variceal upper GI bleeding. The participants were allocated to receive octreotide or placebo and pantoprazole concomitantly. The study was conducted in Mofid Children’s Hospital, Tehran, Iran, during February 2019 - December 2019. Patients with hepatic failure, liver stigma, and coagulopathy due to thrombocytopenia were excluded. Demographic, clinical, and preclinical data were recorded in prepared sheets. All the patients were followed until therapy discontinuation. P-value < 0.05 was considered significant. Results: Forty-three patients with a mean age of 4.98 ± 3.79 years and confirmed non-variceal upper GI bleeding were included in the present study. Most patients had no specific etiology for their bleeding episodes. Patients in the intervention and control groups received pantoprazole in comparable doses. No differences were observed between the two groups in terms of baseline hemoglobin values (P = 0.08), while final hemoglobin values were significantly higher in the intervention group (P = 0.014). The bleeding duration was not significantly different between the two groups (P = 0.99). Moreover, none of the cases showed adverse drug reactions due to octreotide infusion. Conclusions: Our study demonstrated that octreotide did not alter bleeding duration or need for blood transfusion. However, positive results were observed for hemoglobin, affecting blood loss volume.
The Effect of Strenuous Endurance Training in Combination with Zingiber Supplementation on Serum Interleukin-17 and Skeletal Muscle Total Oxidant in Male Rats
Authors: Usefpour Mozhgan , Ghasemnian Aghaali , Rahmani Ahmad
Published: April 2022

Background: This study aimed to investigate the effect of 8 weeks of strenuous endurance training (ET) with ginger extract supplementation on resting levels of serum interleukin-17 (IL-17) and total antioxidant capacity (TAC) of muscle in male Wistar rats. Methods: Forty rats were divided randomly into five groups: control (n = 8), Sham (n = 8), zingier (n = 8), ET (n = 8), and ET + zingiber (n = 8). The training protocols consisted of ET on a treadmill for 8 weeks (5 days a week). Ginger extract (100 g/kg body weight) was injected subcutaneously in the ginger group and ET + zingiber group for 8 weeks (3 days a week) from the beginning of the second week. Forty-eight hours after the last training session and 4 hours of overnight fasting, blood and tissue samples were collected. The serum concentration of IL-17 was measured using the ELISA method by BT kit, China. TAC concentration of muscle tissue was measured using the colorimetric method with ZELBIO kits, Germany. One-way analysis of variance (ANOVA) and Scheffe’ post hoc tests were used to analyze the data. Results: This study showed that after 8 weeks, serum levels of IL-17 were significantly higher in the ET groups than in the control group (P < 0.05). Also, serum IL-17 was significantly decreased in the ET + ginger group than the endurance group (P < 0.05). However, there was no significant difference in TAC of muscle tissue in the ET, ginger, and ET + ginger groups than the control group (P < 0.05). Conclusions: This study demonstrated that 8 weeks of endurance training, combined with ginger supplementation, significantly reduced the inflammatory marker of IL-17. Therefore, ginger supplementation with endurance training seems to have a protective role against oxidative and inflammatory factors.
Chekhov's prose in the opera of the late XX-beginning. XXI centuries .
Authors: Shoniezova Dinara Makhmadovna
Published: April 2022

As the world theatrical practice of the last decades shows, it is the legacy of A.P. Chekhov that is an inexhaustible source of inspiration for many directors and composers. There is a huge number of works devoted to the topic "Chekhov and music". The musicality of Chekhov's prose is one of the most frequent topics in philological and musicological studies. Plays, novels, and short stories by the author have more than once become an occasion for new creations in the opera house. In this article, the author examines the famous operas of composers of the turn of the XX-XXI centuries based on the prose of A. Chekhov. The works are arranged according to the principle of differences between the plot plot and the libretto of operas from the literary source. In foreign musicology, the genre transformation of opera, in which the literary component becomes the main factor of centralizing unity, has been called literary (the term of K. Dahlhaus). In the most general sense, this genre should be understood as a reliable musical version in accuracy or in the abbreviation of the literary source. In Russian musicology, literary opera is a little-studied area of music history, which allows us to speak about the scientific novelty of the presented material. Thus, in the article the author comes to the conclusion that operas based on A.P. Chekhov stand apart in the implementation of the genre of literary opera in the domestic theater of the selected period. Based on the analysis, the author identifies three types of literary opera, which allow to characterize the method of composers' work with the literary source.
Song creativity of Suleiman Aleskerov
Authors: Niftiyeva Ulfat Namiq
Published: April 2022

The subject of the research is the study of the specific stylistic features of the songwriting of the outstanding composer Suleiman Aleskerov, who played an exceptional role in the prosperity and development of the musical art of Azerbaijan, the study of the role of vocal music in the composer's work, the identification of the main features of his songs by analysis. The object of the study is the songwriting of Suleiman Aleskerov. In this context, the object of the study is to study the composer's attitude to the sources of song creativity, to the sources of folk music, to identify the national characteristics of the musical language of his songs, its originality. His songwriting is analyzed from the point of view of thematic and genre diversity, special attention is paid to the study of musical form, rhythm, mugham, melodic language of his songs. The main results of the study are that, despite the fact that Aleskerov's songs differ in musical structure, textural features, the definiteness of the national mugham is clearly expressed in them, the content of the melody, the intonation core is revealed. The author's special merits in studying the topic are that the main feature manifested in the melodies of songs is associated with the appearance of such mughams as shchur, segah, shushtar, bayat shiraz, which occur above the harmonic structure of a major or minor. Although his lyrical songs show the qualities inherent in folk songs, they differ in musical language. So, here the peculiarities of the romance genre come to the fore, and not folk songs. This is especially evident in the widely developed, smooth melody, which in its style is associated with mugham. The scientific novelty of the research lies in the fact that the songwriting of Suleiman Aleskerov was studied, the musical language of his songs and the stylistic features of the composer were revealed. The composer's songs in various genres were analyzed, the themes of his work, genre features, creative attitude to folk music and mugham were revealed.
The study of the creative directions of the art of the twentieth century in the classes of the theoretical cycle of disciplines in music universities and colleges
Authors: Sorokina Ekaterina Aleksandrovna
Published: April 2022

The music of the twentieth century is characterized by multidimensional concepts, a variety of composing techniques, a complex content context, which makes it difficult to master the studied material in the lessons of theoretical disciplines of music educational institutions. The purpose of the article is to substantiate the specifics of studying the musical art of the twentieth century within the disciplines of the theoretical cycle of the modern multilevel system of music education. The main method of research was a complex, requiring an interdisciplinary approach (art history, musicology, cultural studies, pedagogy, music pedagogy). The scientific novelty of the study consists in identifying optimal approaches to mastering one of the most difficult periods of composer creativity for students to perceive. As a result, a thesis formulation of the categorical and conceptual apparatus of the studied creative trends, trends and compositional styles with an accompanying illustrative series, both auditory and visual, is proposed. The practical significance of the research lies in the fact that the methodological approaches presented in the work in the study of musical art of the twentieth century will be in demand within the framework of theoretical disciplines at different levels of musical education. The materials are addressed primarily to top-level teachers (bachelor's degree, within the framework of studying the disciplines "History of Foreign Music" and "Music of the twentieth century"), however, they may be in demand, including fragmentary, and in college, and with some adaptation in high schools of music and art schools when studying the composition of the twentieth century centuries.
The importance of the principles of proceedings in cases of administrative offenses and the form of their consolidation
Authors: Nobel Artem
Published: April 2022

The subject of the article is the norms of legislation on administrative offenses: the Code of the Russian Federation on Administrative Offenses, the Constitution of the Russian Federation, the European Convention for the Protection of Human Rights and Fundamental Freedoms of 04.11.1950, regulating the principles of proceedings in cases of administrative offenses. The author carried out a comparative analysis of scientific views on the ways and forms of fixing the principles of proceedings in cases of administrative offenses, as well as the relationship of the concepts of "rule of law" and "legal principle". The methodological basis was made up of general scientific methods of cognition: analysis, synthesis, comparison and private scientific methods of cognition: formal legal, comparative legal. The author notes the special position of the principles of proceedings in cases of administrative offenses as regulatory entities and comes to the conclusion about their importance for the regulation of proceedings in cases of administrative offenses. The article substantiates the position on the need to distinguish between the legal principles of proceedings in cases of administrative offenses, enshrined in the legislation on administrative offenses and the principles of a non-legal nature existing in the science of administrative law. The opinion is expressed that the objectification of the principles of proceedings in cases of administrative offenses in the legislation on administrative offenses is carried out through textual and semantic methods of normative expression.
Democracy as an institution for revealing the will of the people
Authors: Kravchenko Oleg Aleksandrovich
Published: April 2022

The subject of the study is democracy and approaches to its definition through the prism of revealing the will of the people, as well as issues of the implementation of democracy in constitutional and legal reality. The author examines in detail the necessary and sufficient conditions for the implementation of democracy on the basis of three approaches. The first approach defines democracy as the participation of all (the people) in public administration. The second approach is widespread in jurisprudence and expresses the totality of a different set of legal conditions and procedures, as well as relationships regarding the delegation of power from the people to the public administration. The third approach, which has appeared quite recently in science, is a kind of synthesis of the first two, but is focused on the result of procedural aspects of democracy. В  The thesis concept is based on the following political and legal postulates of understanding democracy, state power and elections: 1) the objective regularity of any state power is its desire to continue to possess it; 2) a democratic state is more effective than an undemocratic one, since it has legal institutions that allow limiting the usurpation of state power by any one political force; 3) a democratic state differs from an undemocratic one by the possibility of changing political power nonviolently through elections, the result which is not predetermined in advance. By virtue of the first postulate, in the electoral systems of states, there is a possibility of seizing and retaining state power in violation of democracy by distorting the will of the people, since the state authorities of the previous composition, acting as organizers of the elections, are interested in maintaining the status quo. In this connection, a comprehensive mechanism is needed to limit the possibility of usurpation of state power during elections at the stages of organizing voting, summarizing its results and establishing the results of elections (referendums).
Legal status of the State Budgetary Institution Of The Voronezh Region "Center For State Cadastral Valuation Of The Voronezh Region"
Authors: Kolmakova Kristina Aleksandrovna
Published: April 2022

Starting from January 1, 2017, the functions for the direct implementation of the state cadastral valuation of real estate objects were transferred to specialized organizations of the subjects of the Russian Federation created in the form of state budgetary institutions.On the one hand, the actual work on the valuation of real estate is being withdrawn from the sphere of public procurement, which implies the refusal to involve professional appraisers in determining the value of real estate objects, that is, persons whose main purpose is to make a profit. On the other hand, the functions and powers of the authorities in the field under study are delegated to specialized organizations that do not have the status of a public authority. В В  The article proves that the legal status of such institutions should be defined as a "legal entity of public law". At the same time, their activities are based on the concept of delegating state powers to private individuals. At the moment, there are contradictions between approaches grounded in legal science to the status of legal entities of public law, as well as to the procedure for delegating (outsourcing) certain power functions, on the one hand, and the legislative consolidation of the legal status of budgetary institutions performing functions in the field of state cadastral valuation, on the other.In addition, the concept of legal entities of public law is relatively new for domestic legislation and legal science.
Proving in cases of administrative offenses provided for in Article 6.1.1 of the Administrative Code of the Russian Federation (Beatings)
Authors: Vodianaia Mariia , Lyashuk Anna Valer'evna
Published: April 2022

The object of the study is a set of administrative and legal relations arising in the field of the implementation of tasks by the police and functions for bringing to administrative responsibility for beatings. The subject of the study is the norms of Russian legislation regulating the process of collecting evidence in cases of this category, as well as the problems of law enforcement practice caused by the lack of a unified approach to the formation of the evidence base. The authors consider the features of the administrative and jurisdictional activities of the police aimed at bringing the perpetrators of beatings to administrative responsibility. In the course of the study, private scientific methods were used, such as formal-logical, statistical research methods; analysis of documents. Based on the analysis of law enforcement practice, as well as court decisions made by courts of general jurisdiction and justices of the peace, the article reveals the features of collecting and forming an evidence base that allows for comprehensive, complete, objective and timely clarification of the circumstances of cases involving persons guilty of battery to administrative responsibility under Article 6.1.1 of the Administrative Code of the Russian Federation, as well as its resolution is in accordance with the law. The trends that have developed to date in judicial practice on the consideration of cases of these administrative offenses are analyzed and determined. The results of the study are correlated with the legal positions of the higher courts.
Legal regulation of the use of information and communication technologies in the activities of public authorities
Authors: Lolaeva Al'bina Slavovna
Published: April 2022

The article examines the issues of legal regulation of the use of information and communication technologies in the activities of public authorities. The relevance of the topic is due to the universal digitalization of public relations, including the activities of public authorities. The widespread informatization of various spheres of society, their economic activities, the development and introduction of modern data transmission devices, the expansion of computer networks led to a sharp increase in the volume of processed information, and modern society began to be called informational. The process of informatization of society is gradually taking place. Various information and communication technologies are also actively used in the field of public administration in Russia. The processes of informatization and information support are increasingly active in the digital economy of Russia. Technologies and their application are turning from a specialized professional field into a key issue in the sphere of public administration. In the general understanding, information and communication technologies are a process that includes a set of tools and methods for the implementation of operations for the collection, registration, accumulation, processing and transmission of information based on hardware and for the purpose of solving management tasks. The author formulates the conclusion that information and communication technologies are increasingly being used in the activities of public authorities. Informatization of the activities of public authorities in the Russian Federation is an indispensable and important stage in the formation of the information society, as well as the leading direction of reforming the entire system of public administration.