bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrating random forest and crop modeling improves the crop yield prediction of winter wheat and oil seed rape
Authors: Dhillon Maninder Singh , Dahms Thorsten , Kuebert-Flock Carina , Rummler Thomas , Arnault Joel , Steffan-Dewenter Ingolf , Ullmann Tobias
Published: January 2023

The fast and accurate yield estimates with the increasing availability and variety of global satellite products and the rapid development of new algorithms remain a goal for precision agriculture and food security. However, the consistency and reliability of suitable methodologies that provide accurate crop yield outcomes still need to be explored. The study investigates the coupling of crop modeling and machine learning (ML) to improve the yield prediction of winter wheat (WW) and oil seed rape (OSR) and provides examples for the Free State of Bavaria (70,550 km2), Germany, in 2019. The main objectives are to find whether a coupling approach [Light Use Efficiency (LUE) + Random Forest (RF)] would result in better and more accurate yield predictions compared to results provided with other models not using the LUE. Four different RF models [RF1 (input: Normalized Difference Vegetation Index (NDVI)), RF2 (input: climate variables), RF3 (input: NDVI + climate variables), RF4 (input: LUE generated biomass + climate variables)], and one semi-empiric LUE model were designed with different input requirements to find the best predictors of crop monitoring. The results indicate that the individual use of the NDVI (in RF1) and the climate variables (in RF2) could not be the most accurate, reliable, and precise solution for crop monitoring; however, their combined use (in RF3) resulted in higher accuracies. Notably, the study suggested the coupling of the LUE model variables to the RF4 model can reduce the relative root mean square error (RRMSE) from −8% (WW) and −1.6% (OSR) and increase the R2 by 14.3% (for both WW and OSR), compared to results just relying on LUE. Moreover, the research compares models yield outputs by inputting three different spatial inputs: Sentinel-2(S)-MOD13Q1 (10 m), Landsat (L)-MOD13Q1 (30 m), and MOD13Q1 (MODIS) (250 m). The S-MOD13Q1 data has relatively improved the performance of models with higher mean R2 [0.80 (WW), 0.69 (OSR)], and lower RRMSE (%) (9.18, 10.21) compared to L-MOD13Q1 (30 m) and MOD13Q1 (250 m). Satellite-based crop biomass, solar radiation, and temperature are found to be the most influential variables in the yield prediction of both crops.
Continuous high-frequency pesticide monitoring in a small tile-drained agricultural stream to reveal diel concentration fluctuations in dry periods
Authors: la Cecilia Daniele , Dax Anne , Ehmann Heinz , Koster Margie , Singer Heinz , Stamm Christian
Published: January 2023

Plant Protection Products (PPPs) pose a threat to surface water quality worldwide. While small streams compose the majority of the stream lengths and are crucial for biodiversity, their exposure patterns to PPPs and transformation products (TPs) are largely understudied in dry periods. This knowledge gap can lead to ineffective monitoring strategies for addressing water quality issues. Here, we focus on two extended dry periods the in-depth analysis of a unique continuous high-frequency (20 min) concentrations dataset for 60 PPPs and TPs. The dataset refers to the monitoring of a small tile-drained agricultural stream over 41 days from May to July in 2019. The overall 2560 concentration data per compound obtained with the on-site mass spectrometer MS2Field platform revealed: (i) surprisingly high maximum concentrations (hundreds to thousands ng/l for some compounds) over extended periods of time, (ii) novel diel fluctuations of concentrations in the order of hundreds of ng/l for some PPPs and TPs, (iii) unexpected high concentrations (up to 220 ng/l) of a legacy compound (the fungicide oxadixyl withdrawn from the Swiss market in 2005). We hypothesized the cause of our findings was rooted in high PPPs levels in the shallow groundwater. To investigate this, we complemented our measurements with the long-term Swiss national monitoring program integrating samples over 14 days at the same location. The continuous long-term measurements found a few PPPs all year-round, thus indicating the presence of persistent contamination sources in the catchment. Next, we collected spatially distributed grab samples in tile drain outlets and stream water on a dry summer day in 2020. The dry-day campaign not only confirmed our hypothesis given the measured high concentrations of PPPs and TPs in tile drain outlets but also highlighted large spatial variability in measured concentrations along the stream. Hereafter, we highlight the questions that different monitoring schemes can answer in dry conditions. This information was relevant to observe for the first time, and thus foresee, the dynamic patterns of PPPs and TPs in the aquatic ecosystem in dry summer conditions, with the latter generally becoming more frequent due to climate change.
Past and future evolution of the onshore-offshore groundwater system of a carbonate archipelago: The case of the Maltese Islands, central Mediterranean Sea
Authors: De Biase Michele , Chidichimo Francesco , Micallef Aaron , Cohen Denis , Gable Carl , Zwinger Thomas
Published: January 2023

Offshore freshened groundwater (OFG) is groundwater with a salinity below that of seawater that is stored in sub-seafloor sediments and rocks. OFG has been proposed as an alternative solution to relieve water scarcity in coastal regions and to enhance oil recovery. Although OFG has been documented in most continental margins, we still have a poor understanding of the extent and flow characteristics of OFG systems, and their evolution through time. In view of the general absence of appropriate field data, paleohydrogeological models have been used. The majority of these models are based on 2D approaches, and they rarely consider the future evolution of OFG systems, especially in response to predicted climate change. Here we utilize recently acquired geological, geophysical and hydrogeological data from onshore and offshore the Maltese Islands, and employ 2D and 3D numerical models, to: (i) reconstruct the evolution of the onshore-offshore groundwater system during the last 188 ka, (ii) predict the evolution of the OFG system in response to climate-related changes. We show that the mechanisms emplacing OFG include a combination of active meteoric recharge at present as well as at sea-level lowstands. The Maltese onshore-offshore groundwater system is relatively dynamic, with 23% of groundwater being preserved in the last 18 ka. The control of geology is expressed by the more prevalent distribution of OFG north of the Great Fault, which is associated to the occurrence of low permeability units, and the asymmetry of the groundwater lens during the 18 ka lowstand. A 30% decrease in recharge predicted in the coming 100 years will diminish OFG extent by 38%, whereas sea-level rise will play a negligible role. At present the estimated volume of OFG is 1 km3, which could potentially provide an alternative supply of potable water to the Maltese Islands for 75 years. Exploitation of OFG with minimal salinization of onshore groundwater bodies would require locating pumping wells close to the coast.
“Even more than that, men love cars”: “Car guy” memes and hegemonic masculinity
Authors: Dundes Lauren
Published: January 2023

The construction of gender identities occurs through a variety of social forces, including memes widely circulated on social media. Beyond the function of internet memes as entertainment, they also promote gender-based bonding through humor in ways that encourage performative gender roles central to self-image. Decoding memes as a form of contemporary data reveals desires and fears, both conscious and unconscious, that underlie dramaturgical performances supporting hegemonic masculinity. In the case of “car guys,” car aficionados whose passion for cars is integral to their identity, memes reflect the group's aspirational presentation of self, including cars, as a symbolic physical embodiment of hegemonic masculinity. This semiotic study of 60 car guy memes shared on social media uncovered recurrent motifs centered around cars' ability to affirm men's position in the metaphorical driver's seat. Flashy cars were often portrayed as more desirable than women, a sentiment encapsulated by the meme, “Men love women, but even more than that, men love cars.” This novel analysis of memes explores the ostensible male preference for fantasy cars over emotionally risky relationships. Two salient themes relevant to conceptions of masculinity emerged: (1) car guys' apprehensions about male–female interdependence and (2) frustration with women's discretion in meeting men's emotional and sexual needs. Memes as a cross-sectional, unfiltered data source provide insight into the need to reconcile car culture with gender equality.
What do the narratives tell us? Exploring the implementation of the Athena SWAN Ireland Charter
Authors: O'Mullane Monica
Published: January 2023

Due to the systemic inequalities enduring in career progression pathways in the Irish higher education sector, the Athena SWAN Ireland Charter (ASIC), a gender equality accreditation program, is being implemented. Using a theoretical approach, blending insights from feminist institutionalism with literature on the role of narratives in policy implementation, this article reveals the complex nature of subjective engagement with policy implementation processes. This article discusses an empirical study of Athena SWAN Ireland Charter implementation across three purposively chosen Irish universities, interviewing 26 key institutional actors tasked with implementing the ASIC locally. Narrative themes emerging as dominant from the data include a lack of operational knowledge, desire for a nationally contextualized program, ambiguity, championing, “happy talk,” and identifying points of resistance. Literature on the role of narrative accounts highlighting a diversity of perceptions in policy and program implementation is strengthened by this study's findings. A feminist institutionalist lens highlight the gendered nature of the operationalization of the Charter work and the vague and detached “happy talk” engaged predominantly by senior men leaders. Findings from this empirical study highlight the importance of exploring the narrative accounts of key actors in order to gain a holistic understanding of the nuanced implementation process, beyond the normative assumptions inherent in the Charter implementation.
Digital work platform: Understanding platforms, workers, clients in a service relation
Authors: Cruz Sofia Alexandra , Gameiro Ana
Published: January 2023

The rapid growth of digital economic activity had led to considerable scholarly interest in the phenomenon of platforms. Evidence shows how digital work platforms constitute one of the most relevant changes that have occurred in recent years and assume the condition of actors with an important presence in national and global work markets. However, these changes cannot be understood by focusing only on the work sphere, as the sphere of consumption is also central to this debate. In fact, the new ways of organizing, dividing and coordinating work on digital platforms are interconnected with specific modalities of consumption of the services made available by them. This article argues that a service relation approach allows an understanding of what is happening on digital work platforms, both in terms of the structural and conjunctural configurations of the interrelationships between platforms, workers and clients, as well as their social and economic consequences. This approach allows the analysis of the web of interdependencies between distinctive types of platforms, workers and clients, and to discuss how changes longitudinally within it are conditioned by the very transformations inherent to the platforms market. Thus, future research needs to explore the network of the voices of platforms, workers and clients in order to produce a robust analysis of these triangular relations as well as of the challenges regarding the differences and interconnections between algorithmic and human management.
Potential and limitations of digital ethnographic research: A case study on a web community
Authors: Masullo Giuseppe , Coppola Marianna
Published: January 2023

Introduction

This work aims at transposing ethnographic research into digital contexts to probe its potential and limitations in a specific field of study: that of sexuality, particularly suited to ethnographic exploration. We chose as our case study a web community of Italian asexual people. As we shall see, this allowed us to simultaneously explore both the various techniques called into play in digital ethnography and the digital as a specific sphere within which sexuality takes on a very peculiar meaning. Digital sociality is paramount for the definition of imaginaries, meanings, and practices that could not be explored elsewhere. This is due to the implicit characteristics of the population studied, which does not find corresponding physical spaces of aggregation.

Methods

The paper will present the research design using this specific case study to address some of the typical dilemmas that researchers face when following the digital ethnographic approach and will explore the research results as an example of the kind of analysis available with the information and data collected through this method.

Results and discussion

The conclusions will attempt to briefly outline the shortfalls and advantages of this method, considering its application to this specific field of study.
Gender in mental health: Relationship of spirituality, social support, and COVID-19-related fear among heterosexual and LGBTQ+ youth
Authors: Alibudbud Rowalt
Published: January 2023

Introduction

The youth is a vulnerable population to COVID-19-related fear. Among them, those with LGBTQ+ identities are at higher risk. Given the posited protective effects of spirituality and social support on fear, this study explored their effects on COVID-19-related fear among heterosexual and LGBTQ+ youth.

Materials and methods

This cross-sectional study recruited 137 respondents Filipinos aged 18–30 years old. The respondents answered a survey containing a sociodemographic questionnaire, 12-items Multidimensional Scale of Perceived Social Support (MSPSS), 20-items Core Dimensions of Spirituality Questionnaire (CDSQ), and 7-items Fear of COVID-19 Scale (FCS). After, the data were analyzed using means, frequencies, Mann-Whitney U-tests, and correlation coefficients.

Results

Social support from friends was negatively correlated with COVID-19-related fear among heterosexual respondents, R = −0.219, p = 0.029. Search for meaning positively correlated with COVID-19-related fear among LGBTQ+ respondents, R = 0.395, p = 0.016. Heterosexual respondents also have a higher belief in God (U = 1,004, p < 0.001) and feelings of security (U = 1,110.5, p < 0.001) than their LGBTQ+ counterparts.

Discussion

These findings suggest that social support from friends is protective against COVID-19-related fear among heterosexual youth but not among LGBTQ+. In addition, a high search for meaning can heighten COVID-19-related fear among LGBTQ+. Finally, these findings can be explained by the higher rates of discrimination against LGBTQ+ than heterosexual youth. Thus, gender-responsive mental healthcare is needed to address the youth's fears as society recovers from the pandemic.
The case for solar full-disk spectral diagnostics: Chromosphere to corona
Authors: Ugarte-Urra Ignacio , Young Peter R. , Brooks David H. , Warren Harry P. , De Pontieu Bart , Bryans Paul , Reep Jeffrey W. , Downs Cooper , Winebarger Amy R. , Tun Samuel D.
Published: January 2023

In the context of the recent call for white papers for the Decadal Survey for Solar and Space Physics (Heliophysics) 2024–2033, we present the argument that spatially-resolved spectral diagnostics over the full solar disk should be made a high-priority goal in Heliophysics and lead to the development of a mission concept that has the potential to become a cornerstone of the Heliophysics System Observatory (HSO). We claim that a mission providing consistent full-disk sampling of plasma properties (Doppler-shifts, non-thermal velocities, electron densities, elemental composition, etc.) of the chromosphere-corona system at the dynamic timescales of solar eruptive phenomena will revolutionize the field by adding the spectral diagnostics capability to the highly successful concept of full-disk imaging, everywhere, all the time, represented by the Solar Dynamics Observatory (SDO). We argue for it to be developed by the end of the current Decadal Survey cycle around the lessons learned from spectroscopic missions in the current NASA development pipeline, that include innovative strategies for faster integration of large fields-of-view, and comprehensive temperature coverage.
Biomechanics and lower limb function are altered in athletes and runners with achilles tendinopathy compared with healthy controls: A systematic review
Authors: Quarmby Andrew , Mönnig Jamal , Mugele Hendrik , Henschke Jakob , Kim MyoungHwee , Cassel Michael , Engel Tilman
Published: January 2023

Achilles tendinopathy (AT) is a debilitating injury in athletes, especially for those engaged in repetitive stretch-shortening cycle activities. Clinical risk factors are numerous, but it has been suggested that altered biomechanics might be associated with AT. No systematic review has been conducted investigating these biomechanical alterations in specifically athletic populations. Therefore, the aim of this systematic review was to compare the lower-limb biomechanics of athletes with AT to athletically matched asymptomatic controls. Databases were searched for relevant studies investigating biomechanics during gait activities and other motor tasks such as hopping, isolated strength tasks, and reflex responses. Inclusion criteria for studies were an AT diagnosis in at least one group, cross-sectional or prospective data, at least one outcome comparing biomechanical data between an AT and healthy group, and athletic populations. Studies were excluded if patients had Achilles tendon rupture/surgery, participants reported injuries other than AT, and when only within-subject data was available.. Effect sizes (Cohen's d) with 95% confidence intervals were calculated for relevant outcomes. The initial search yielded 4,442 studies. After screening, twenty studies (775 total participants) were synthesised, reporting on a wide range of biomechanical outcomes. Females were under-represented and patients in the AT group were three years older on average. Biomechanical alterations were identified in some studies during running, hopping, jumping, strength tasks and reflex activity. Equally, several biomechanical variables studied were not associated with AT in included studies, indicating a conflicting picture. Kinematics in AT patients appeared to be altered in the lower limb, potentially indicating a pattern of “medial collapse”. Muscular activity of the calf and hips was different between groups, whereby AT patients exhibited greater calf electromyographic amplitudes despite lower plantar flexor strength. Overall, dynamic maximal strength of the plantar flexors, and isometric strength of the hips might be reduced in the AT group. This systematic review reports on several biomechanical alterations in athletes with AT. With further research, these factors could potentially form treatment targets for clinicians, although clinical approaches should take other contributing health factors into account. The studies included were of low quality, and currently no solid conclusions can be drawn.
Advancing feminist innovation in sport studies: A transdisciplinary dialogue on gender, health and wellbeing
Authors: Thorpe Holly , Bekker Sheree , Fullagar Simone , Mkumbuzi Nonhlanhla , Nimphius Sophia , Pape Madeleine , Sims Stacy T. , Travers A.
Published: January 2023

Athlete health and wellbeing requires a holistic, multidimensional approach to understanding, supporting, and treating individual athletes. Building more supportive, inclusive, and equitable environments for the health and wellbeing of women and gender expansive people further requires gender-responsive approaches that promote broader cultural change. Feminist sport and exercise medicine practitioners, sports scientists, and social science researchers are increasingly coming together in their efforts to do this work. However, working across disciplines inevitably includes an array of ontological, epistemological, and political challenges. In this paper, we offer a curated ‘dialogue’ with a group of feminist scholars engaged in research and practice across disciplines, bringing them together to discuss some of the most pressing gendered issues in sport today (i.e., ACL injury, concussion, menstruation in sport, mental health, gender categories). In so doing, we amplify the voices of those working (empirically and clinically) at the disciplinary intersections of gender, sport and health, and learn about some of the current and future possibilities for transdisciplinary innovations and strategies for building (responsiveness to) cultural change.
Assessing complementary synergies for integrated crop–livestock systems under conservation agriculture in Tunisian dryland farming systems
Authors: Dhehibi Boubaker , Fouzai Ayoub , Frija Aymen , Adhim Mohamed Abdel , M'hamed Hatem Cheikh , Ouerghemmi Hassen , Rekik Mourad
Published: January 2023

The aim of this paper is twofold. The first objective is to measure the technical efficiency of mixed crop-livestock (CL) smallholder producers operating under conservation agriculture systems in Tunisian rainfed areas. The second objective is to explore complementarities, synergies, and economies of diversification across the different production system components of these crop-livestock producers using the cross-partial derivative framework of output variables in the distance function. A simple random sampling process was employed to select and survey 59 CL smallholders operating under conservation agriculture. The collected data were analyzed using a stochastic input distance function in which synergies were estimated based on the second cross-partial derivative concept of output variables in the distance function. Results show that technical inefficiencies are significant in integrated crop-livestock systems, and there is evidence that economic diversification provides a productivity buffer against climate change threats. As a sustainable intensification strategy, this integrated system also offers a potential advantage. The results further contribute to the debate on crop diversification vs. specialization. Although an enhanced system integration could be a financially and ecologically viable option for mixed crop-livestock systems, more pathways for profitable and viable diversification of cereal-based or orchard-based systems remain to be explored.
Food systems in depressed and contested agro-territories: Participatory Rural Appraisal in Odemira, Portugal
Authors: Horstink Lanka , Schwemmlein Kaya , Encarnação Miguel F.
Published: January 2023

Farming regions in Europe, particularly in the South, are increasingly feeling the effects of climate change due to factors such as drought, extreme weather events, and desertification, with severe consequences for food security and food sovereignty. Additionally, decades of rural mismanagement have left countless of these farming territories severely depressed as well as at the mercy of competition for their natural resources. This paper presents and discusses the results of a Participatory Rural Appraisal conducted in the region of Odemira, Southwest Portugal. Rooted in the frameworks of agroecology and food democracy, this mixed methodology aims to support people in multiply stressed agro-territories to diagnose the state of their food systems and agroecosystems from a democratic and ecological point of view and engage local actors in imagining fairer and healthier food futures for their regions. Local food actors were invited to identify and qualify the main problems in the region's food systems, complemented by an agroecological assessment of farm production systems. The results of the study confirm the status of Odemira as a depressed and contested agro-territory, whose social, economic, and ecological vulnerability is being compounded by the clash between the model of traditional smallholder farming and that of large-scale intensive agriculture. The study also shows the potential of sustainable farming practices as well as collaboration between the different food actors to support an agroecological transition in the region. However, to jointly realise food democracy and food system sustainability, the tensions resulting from the current political support for hyper-industrialisation and the lack of democratic, institutional, and legal mechanisms available to local actors will need to be addressed head-on.
Cervical single open-door laminoplasty with or without local lateral mass screw fixation and fusion to treat cervical spinal cord injuries accompanied by segmental spinal canal stenosis
Authors: Yu Zihao , Xie Hongwei , Ouyang Ziyu , Zhang Hua
Published: January 2023

Study Design

Retrospective.

Objectives

To investigate the efficacy of cervical single open-door laminoplasty with and without local lateral mass screw fixation and fusion as treatments for cervical spinal cord injuries accompanied by multisegmental spinal canal stenosis.

Setting

The Second Affiliated Hospital, School of Medicine, Zhejiang University.

Methods

Of all enrolled patients, 42 formed a stable group who underwent cervical single open-door laminoplasty alone and 14 formed an unstable group who underwent the procedure combined with lateral mass screw fixation and fusion. Neurological function was evaluated before surgery, at discharge, and at final follow-up using the American Spinal Cord Injury Association (ASIA) impairment scale and the Japanese Orthopedic Association (JOA) score.

Results

ASIA scores reflected improved neurological function in 52.5% of the stable group (15 with grade-D and 4 with grade-A injuries did not improve) and 45.5% of the unstable group (3 with grade-D and 3 with grade-A injuries did not improve). Postoperative JOA scores reflected 19.1% ± 21.6% improvement in the stable group and 18.6% ± 18.4% improvement in the unstable group (P > 0.05). Final follow-up JOA scores reflected 49.2% ± 31.7% improvement in the stable group and 47.1% ± 39.2% improvement in the unstable group (P > 0.05).

Conclusions

Laminoplasty combined with local fusion aided the treatment of unstable cervical spinal cord injuries and spinal stenosis. Such stenosis is the main pathological factor causing multiple spinal cord compressions in patients with cervical spinal cord injuries.
Effects of robotic and laparoscopic-assisted surgery on lymph node dissection and quality of life in the upper third of gastric cancer: A retrospective cohort study based on propensity score matching
Authors: Fu Jingxiao , Li Yi , Liu Xuechao , Jiao Xuelong , Qu Hongyu , Wang Yuhao , Niu Zhaojian
Published: January 2023

Objective

The objective of this study was compare the effects of robot-assisted and laparoscopic-assisted surgery on lymph node dissection and quality of life in upper third gastric cancer patients undergoing radical total gastrectomy.

Methods

The clinical and follow-up data of 409 patients with upper third gastric cancer who underwent total gastrectomy from July 2016 to May 2021 were enrolled. The patients were divided into a robotic group (n = 106) and a laparoscopic group (n = 303). Age, sex, body mass index, American Society of Anesthesiologists score, tumor size and location, pathological type, cT, cN, and cTNM were adjusted to offset selection bias. The patient characteristics, operative procedures, surgical outcomes, oncologic and pathologic outcomes, number of lymph node dissections, quality of life assessment, and nutritional status were compared between the two groups.

Results

After propensity score matching, 61 cases were included in the robotic group and 122 cases were included in the laparoscopic group. The number of dissected lymph nodes (37.3 ± 13.5 vs. 32.8 ± 11.8, P = 0.022) significantly differed between the two groups. The number of lower mediastinal and subphrenic lymph nodes in the robotic group was greater than that in the laparoscopic group, and the difference was statistically significant (P < 0.001). Compared with the laparoscopic group, the total score of physical symptoms in the robotic group was significantly lower at 6 and 12 months after surgery (P = 0.03 and P = 0.001, respectively). The total social function score at 6 and 12 months after surgery was higher in the robotic group (P = 0.006 and P = 0.022). The quality of life scores were statistically significant only at 3 months after the operation (P = 0.047). A higher patient-generated subjective global assessment (PG-SGA) score is when the score significantly correlated (P < 0.001) with a higher related physical symptoms score, lower social function score, and lower quality of life score.

Conclusion

Compared with laparoscopic radical gastrectomy, robotic radical gastrectomy is safe and feasible. Compared with laparoscopic radical gastrectomy, robotic radical gastrectomy was more refined, was associated with less surgical bleeding, and increased the quality of lymph node dissection. In addition, patients in the robotic group showed better postoperative quality of life.
Femoral and tibial cementless fixation neither increases blood loss nor impedes early functional recovery: A randomized controlled trial
Authors: Cao Jian , Liao Kai , Li Ze-xi , Wang Duan , Chen Jia-li , Wang Hao-yang , Zhou Zong-ke
Published: January 2023

Background

Whether cementless fixation on femoral and tibial components increases blood loss during total knee arthroplasty (TKA) is unclear. The purpose of this randomized controlled trial was to compare blood loss and early functional recovery between patients who underwent cementless or cemented TKA.

Methods

Between November 2021 and April 2022, sixty-one eligible patients at our medical center were randomized to cementless and cemented group. The primary outcome was total blood loss (TBL). Secondary outcomes were drainage, knee swelling, anemia, transfusion, hematological indicators, early functional recovery, and postoperative complications. The early functional recovery included range of motion (ROM), Hospital for Special Surgery (HSS) score, walking distance.

Results

A total of 61 patients were analyzed, of whom 30 underwent cementless fixation. On postoperative day 1, the mean TBL was 394.39 ml (SD 182.97 ml) in the cementless group and 382.41 ml (SD 208.67 ml) in the cemented group (P = 0.863). By postoperative day 3, the corresponding mean TBL was higher at 593.48 ml (SD 230.04 ml) and 603.80 ml (SD 213.16 ml) (P = 0.751). The two groups did not differ significantly in drainage, knee swelling, anemia, levels of hemoglobin or hematocrit or platelets, ROM, HSS score, walking distance, or rates of transfusion or postoperative complications.

Conclusions

Cementless fixation on femoral and tibial components during TKA does not increase blood loss or impede early functional recovery, which suggests that clinicians need not worry about blood loss and early functional recovery when deciding what type of fixation to perform during TKA.

Trial registration

Number: ChiCTR2100052857; Date: November 6, 2021.
Comparison of Robotic-Assisted vs. Conventional Laparoscopy for Para-aortic Lymphadenectomy in Gynecological Malignancies: A Systematic Review and Meta-Analysis
Authors: Zhou Zhengli , Ge Jing , Ye Kefan , Zhang Yifeng , Hu Qian , Wang Limei , Chen Yiwen
Published: January 2023

Background

Robotic-assisted surgery is one of the novel minimally invasive surgical techniques for the treatment of gynecological malignancies. The aim of this systematic review and meta-analysis was to compare the outcomes of robot-assisted vs. conventional laparoscopy for para-aortic lymphadenectomy (PAL) in patients with gynecological malignancies.

Methods

An electronic search in PubMed, Scopus, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar databases was performed for articles, published up to 01st November 2021. Outcomes including operating time (OT), total blood loss (TBL), length of stay (LOS), and complication rate (CR) in robot-assisted vs. conventional laparoscopy were investigated.

Results

A total of nine studies (7 non-RCTs and 2 RCTs) involving 914 participants were included. Of them, 332 patients underwent robotic laparoscopy (robotic group) and 582-conventional laparoscopy (conventional laparoscopy group). A significant decrease in TBL (MD = −149.1; 95% CI: −218.4 to −79.91) [ml] was observed in the robotic group as compared to the conventional laparoscopy group. However, no significant difference was noted for OT, CR, and LOS in the overall findings. Further subgroup analysis showed that the robotic group had a lower OT in mixed histological populations and studies reporting on the extraperitoneal approach. The lower chance of TBL was observed in mixed histological populations and studies involving extraperitoneal approach, Caucasian population, and non-RCTs design.

Conclusions

Robotic laparoscopy has a significant advantage over the conventional laparoscopy approach for PAL in gynecological malignancies. Further prospective observational studies embedded with a large sample size are needed to validate our findings.
Protective efficacy induced by Eimeria maxima rhomboid-like protein 1 against homologous infection
Authors: Wang Mingyue , Tian Di , Xu Lixin , Lu Mingmin , Yan Ruofeng , Li Xiangrui , Song Xiaokai
Published: January 2023

Introduction

Avian coccidiosis, caused by apicomplexan protozoa belonging to the Eimeria genus, is considered one of the most important diseases in the intensive poultry industry worldwide. Due to the shortcomings of live anticoccidial vaccines and drugs, the development of novel anticoccidial vaccines is increasingly urgent.

Methods

Eimeria maxima rhomboid-like protein 1 (EmROM1), an invasion-related molecule, was selected as a candidate antigen to evaluate its protective efficacy against E. maxima in chickens. Firstly, the prokaryotic recombinant plasmid pET-32a-EmROM1 was constructed to prepare EmROM1 recombinant protein (rEmROM1), which was used as a subunit vaccine. The eukaryotic recombinant plasmid pVAX1.0-EmROM1 (pEmROM1) was constructed as a DNA vaccine. Subsequently, 2-week-old chicks were separately vaccinated with the rEmROM1 and pEmROM1 twice every 7 days. One week post the booster vaccination, induced cellular immune responses were determined by evaluating the mRNA level of cytokines including IL-2, IFN-γ, IL-4, IL-10, TGF-β, IL-17, and TNFSF15, as well as the percentages of CD4+ and CD8+ T cells from spleens of vaccinated chickens. Specific serum antibody level in the vaccinated chickens was determined to assess induced humoral immune responses. Finally, the protective efficacy of EmROM1 was evaluated by a vaccination-challenge trial.

Results

EmROM1 vaccination significantly upregulated the cytokine transcription levels and CD4+/CD8+ T cell percentages in vaccinated chickens compared with control groups, and also significantly increased the levels of serum-specific antibodies in vaccinated chickens. The animal trial showed that EmROM1 vaccination significantly reduced oocyst shedding, enteric lesions, and weight loss of infected birds compared with the controls. The anticoccidial index (ACI) from the rEmROM-vaccination group and pEmROM1-vaccination group were 174.11 and 163.37, respectively, showing moderate protection against E. maxima infection.

Discussion

EmROM1 is an effective candidate antigen for developing DNA or subunit vaccines against avian coccidiosis.
SWOT analysis of risk factors associated with introduction of African Swine Fever through vehicles returning after export of pigs
Authors: Gao Yuqi , Nielsen Lisbeth Harm , Boklund Anette Ella , de Jong Mart C. M. , Alban Lis
Published: January 2023

Denmark is a major pig exporter and applies a high level of biosecurity, with washing and disinfecting stations for returning livestock vehicles. The introduction of African Swine Fever (ASF) would have significant economic consequences related to loss of export of live pigs and products thereof. In this study, we focused on the role of empty livestock vehicles returning after exports of pigs for the introduction of ASF. Initially, the current components and measures related to export of livestock were described. Next, analyses of strengths, weaknesses, opportunities, and threats (SWOT) were conducted, covering the components and measures identified. Then, export of pigs was described either through assembly centers or directly from farms. Washing and disinfection, as required and undertaken at the designated stations, constitutes the most important among all risk-reducing measures identified. Recommendations are to: (1) ensure the quality of washing and disinfection through staff training; (2) find new, safe, and more efficient disinfectants; (3) ensure the required temperature, and therefore effect, of the disinfectant and water. It was impossible to assess, the influence of export through assembly centers compared to direct transport. However, through SWOT analyses we identified the strengths and weaknesses of the two pathways. Moreover, components/measures with risks of unknown sizes are also discussed, such as vehicles undertaking cabotage and the current vehicle quarantine periods.
Relationship between engagement with the impossible task, cognitive testing, and cognitive questionnaires in a population of aging dogs
Authors: Khan Michael Z. , Mondino Alejandra , Russell Katharine , Case Beth , Fefer Gilad , Woods Hope , Olby Natasha J. , Gruen Margaret E.
Published: January 2023

Introduction

The aim of this study was to evaluate the engagement of aging dogs with a cognitively challenging and potentially frustrating task (the impossible task). Based on previous observations, we predicted that dogs showing signs of cognitive impairment in other cognitive tests and owner-completed questionnaires would show reduced engagement with the task.

Methods

In this task, dogs were shown a piece of food in a clear container that they could not open; time spent interacting with the container and the experimenter was measured. While the impossible task has not been used as a measure of frustration, the parameters of the test design creates a potential frustrate state, making this assessment appropriate. Thirty-two dogs enrolled in a longitudinal aging study participated in the study. Owners were asked to complete two cognitive dysfunction screening questionnaires (Canine Dementia Scale [CADES] and Canine Cognitive Dysfunction Rating Scale [CCDR]) as well a questionnaire assessing general frustration. Dogs participated in multiple measures of cognitive function as well the impossible task.

Results

Latency to disengage from the impossible task was faster for dogs with higher total (more impaired) CADES (p = 0.02) and total CCDR (p = 0.04) scores. Latency to disengage also correlated with decreased performance in cognitive tests observing social cues (p = 0.01), working memory (p ≤ 0.001), spatial reasoning and reversal learning (p = 0.02), and sustained attention (p = 0.02).

Discussion

The high correlation with several cognitive measures and the ease of administration of this test makes it a useful tool in evaluating canine cognitive dysfunction syndrome, however it is unclear if increased frustration or other cognitive processes are contributing to the observed changes.
Whole blood trace element and toxic metal concentration in dogs with idiopathic epilepsy and healthy dogs: A case-control study
Authors: Rosendahl Sarah , Anturaniemi Johanna , Kukko-Lukjanov Tiina-Kaisa , Vuori Kristiina A. , Moore Robin , Hemida Manal , Muhle Anne , Hielm-Björkman Anna
Published: January 2023

Background

Idiopathic epilepsy (IE) is the most common neurological disease in dogs. Multiple genes and environmental factors interact to cause clinical signs, although the pathogenesis remains poorly understood. Extensive evidence from recent decades shows that trace elements play a role in epilepsy in humans, and recently it was shown for the first time that also dogs with IE have altered trace element status. On the other hand, toxic metals may cause seizures but research on their role in canine IE is lacking. Therefore, we aimed to investigate trace element and toxic metal concentrations in whole blood from dogs that had been diagnosed with IE and compare them to those of healthy dogs.

Materials and methods

Whole blood concentrations of trace elements (selenium, zinc, copper, manganese, iron, and chromium) and toxic metals (arsenic, cadmium, mercury, and lead) were analyzed from 19 dogs that had been diagnosed with IE by board-certified neurologists and 19 healthy control dogs using inductively coupled plasma mass spectrometry. The concentrations in study and control group were compared using the Mann-Whitney U test.

Results

Dogs diagnosed with IE had significantly higher blood copper concentration (P = 0.007), higher copper/zinc ratio (P = 0.04), and higher selenium concentration (P < 0.001), as well as lower chromium concentration (P = 0.01) when compared to healthy dogs. Treatment of IE with potassium bromide was associated with a significant elevation in blood arsenic concentration (P = 0.01).

Conclusion

In conclusion, the present results support the role of altered trace element status in dogs diagnosed with IE and suggest that copper, selenium, and chromium may be involved in the pathogenesis of canine epilepsy or seizures. The results also suggest that potassium bromide may alter arsenic metabolism in dogs.
African animal trypanocide resistance: A systematic review and meta-analysis
Authors: Kasozi Keneth Iceland , MacLeod Ewan Thomas , Welburn Susan Christina
Published: January 2023

Background

African animal trypanocide resistance (AATr) continues to undermine global efforts to eliminate the transmission of African trypanosomiasis in endemic communities. The continued lack of new trypanocides has precipitated drug misuse and overuse, thus contributing to the development of the AATr phenotype. In this study, we investigated the threat associated with AATr by using the major globally available chemotherapeutical agents.

Methods

A total of seven electronic databases were screened for an article on trypanocide resistance in AATr by using keywords on preclinical and clinical trials with the number of animals with treatment relapse, days taken to relapse, and resistant gene markers using the PRISMA checklist. Data were cleaned using the SR deduplicator and covidence and analyzed using Cochrane RevMan®. Dichotomous outputs were presented using risk ratio (RR), while continuous data were presented using the standardized mean difference (SMD) at a 95% confidence interval.

Results

A total of eight publications in which diminazene aceturate (DA), isometamidium chloride (ISM), and homidium chloride/bromide (HB) were identified as the major trypanocides were used. In all preclinical studies, the development of resistance was in the order of HB > ISM > DA. DA vs. ISM (SMD = 0.15, 95% CI: −0.54, 0.83; I2 = 46%, P = 0.05), DA vs. HB (SMD = 0.96, 95% CI: 0.47, 1.45; I2 = 0%, P = 0.86), and HB vs. ISM (SMD = −0.41, 95% CI: −0.96, 0.14; I2 = 5%, P = 0.38) showed multiple cross-resistance. Clinical studies also showed evidence of multi-drug resistance on DA and ISM (RR = 1.01, 95% CI: 0.71–1.43; I2 = 46%, P = 0.16). To address resistance, most preclinical studies increased the dosage and the treatment time, and this failed to improve the patient's prognosis. Major markers of resistance explored include TbAT1, P1/P2 transporters, folate transporters, such as F-I, F-II, F-III, and polyamine biosynthesis inhibitors. In addition, immunosuppressed hosts favor the development of AATr.

Conclusion

AATr is a threat that requires a shift in the current disease control strategies in most developing nations due to inter-species transmission. Multi-drug cross-resistance against the only accessible trypanocides is a major public health risk, justifying the need to revise the policy in developing countries to promote control of African trypanosomiasis.
Trajectories of Posttraumatic Stress Symptoms Among Young Adults Exposed to a Typhoon: A Three-Wave Longitudinal Study
Authors: Shi Wei , Hall Brian J.
Published: January 2023

Objective: We used a latent class growth model to identify distinct PTSS trajectories and correlates of these trajectories among young adults who experienced Typhoon Hato, the strongest storm to strike China in the last 50 years.

Methods: A longitudinal survey (three-waves) was conducted to explore the mental health status and its correlates among young adults exposed to the typhoon. Data from 362 participants were analyzed via a latent class growth model and multinomial logistic regression.

Results: Three distinct classes of PTSS trajectories were identified, including: “resilience” (86.46%), “recovery” (9.12%), and “deterioration” (4.42%). The higher levels of direct typhoon exposure, media use, and posttraumatic growth significantly predicted the higher likelihood of participants being in the “recovery’’ class. In addition, more social support significantly predicted the higher possibility of being in the “resilience” class. Finally, more severe depressive and anxiety symptoms significantly predicted the higher likelihood of being in the “deterioration” class.

Conclusion: Further research should develop interventions to enhance protective factors (e.g., posttraumatic growth, media use), decrease risk factors (e.g., depressive and anxiety symptoms), and thereby prevent PTSS.
Analysis of the Notch Filter Insertion Position for Natural Frequency Vibration Suppression in a Magnetic Suspended Flywheel Energy Storage System
Authors: Hu Hongjin , Wei Jingbo , Wang Haoze , Xiao Peng , Zeng Yuan , Liu Kun
Published: January 2023

The composite material flywheel rotor of a flywheel energy storage system (FESS) has a low natural frequency. When the system suffers from noise interference, the magnetic bearing generates a force with the same frequency as the natural frequency and causes vibration to occur. Thus, it is necessary to suppress the natural vibration of the magnetic suspended (MS) FESS. The LMS adaptive notch filter is generally adopted for vibration suppression. The vibration suppression performance of the system is different when the insertion position of the notch filter is different. This paper analyzes the influence of the notch filter in different insertion positions of the control system. Through the transfer function from noise to magnetic bearing force, theoretical analysis of the influence of different positions of the notch filter is performed. Corresponding experiments are performed in a 500 kW MS FESS prototype. The theoretical analysis is verified experimentally.