bluuebunny/crossref_metadata_2025 huggingface dataset:
REGULATION PECULIARITIES OF UKRAINE FOREIGN ECONOMIC ACTIVITY IN WAR TIMES
Authors:   State University of Trade and Economics, Baryshpol Stefan
Published: September 2023

In the context of martial law, trade in goods in Ukraine requires a number of changes to protect national interests and the domestic market. The purpose of the article is to identify the key features of foreign economic activity regulation in Ukraine during the war. The Global Trade Alert database for the period of research 2009-2023 was used to conduct the study and analyze the regulation of Ukraine's foreign trade. The results indicate a significant increase in the share of Ukraine's exports and imports to European countries, particularly to the EU, and to Asian countries, which required adjustments to the foreign trade regulation policy from 2011 to 2021. During the period under study, trade policy was aimed at implementing liberalization and protectionist measures simultaneously, which were characterized by an average level of efficiency for certain product groups. During the period of martial law in 2022, 10 liberalization measures and 9 protectionist measures were introduced in trade in goods, particularly for certain European countries. The restrictive measures concerned Russia, European countries, Canada, the United States, and other countries, and were aimed at protecting the domestic market. The key sectors of liberalization in 2022 were cereals, products made of polymeric materials, certain types of equipment and machinery, equipment for electricity distribution, and certain types of fabrics. Legal changes during martial law are determined by domestic demand and external supply for certain groups of goods. The key measures regulating trade in goods in Ukraine are tariff measures, including export and import licensing requirements; export quotas and taxes; import tariffs; and domestic import taxation. In general, some of the regulatory measures discriminate against foreign commercial interests, while others ensure liberalization on a non-discriminatory basis. Non-tariff measures related to exports and imports mainly include sanitary and phytosanitary measures, technical barriers to trade, and precautionary measures.
NAVIGATING ETHICAL AND SOCIAL DIMENSIONS OF GLOBAL SUPPLY CHAINS: CHALLENGES AND OPPORTUNITIES
Authors:   Kyiv National Economic University named after Vadym Hetman, Sandul Mariia
Published: September 2023

The globalized nature of supply chains has brought to the forefront various social and ethical implications, demanding heightened attention from researchers, businesses, and policymakers. The article delves into the critical realm of social and ethical considerations in supply chain management, shedding light on the risks, challenges, and opportunities associated with adopting sustainable practices. The article provides the overview of global supply chains’ impact on diverse stakeholders. It explores the multifaceted nature of sustainability and social responsibility in supply chains, encompassing aspects such as labour practices, human rights, environmental responsibility, and transparency. Drawing upon recent case studies and real-world examples, the research studies the risks and challenges that arise from ethical lapses within supply chains. It examines the financial repercussions faced by companies due to reputational damage, consumer backlash, and legal penalties when labour violations, environmental harm, or other unethical practices come to light. In addition to the risks, the article explores the underlying problems and obstacles in implementing socially and ethically responsible supply chain practices. It discusses the complexities of monitoring and auditing supply chains, particularly in regions with weaker regulatory frameworks, and the potential for exploitative practices to thrive unnoticed. The text discusses the increasing demand for socially and ethically responsible prac- tices in global supply chains, driven by consumers, activists, and investors. The article emphasizes the importance of transpar- ency in supply chains to identify potential ethical issues and implement sustainable practices. By exploring the risks, challenges, and opportunities associated with ethical and socially responsible practices, this article aims to contribute to the growing body of research advocating for a more sustainable and equitable approach to supply chain management in the modern era. Overall, the research advocates for ongoing efforts to address ethical and social issues in supply chains to preserve brand value, consumer trust, and financial stability.
CUSTOMS PAYMENTS AS A FISCAL TOOL OF THE STATE: TRENDS AND CHALLENGES OF THE CURRENT PERIOD
Authors:   HEI «Uzhhorod National University», Sochka Kateryna , Palinchak Mykola ,   HEI «Uzhhorod National University»
Published: September 2023

The governments of many countries are facing the urgent task of forming a system of sustainable sources of budget revenues to finance various needs of the state in present conditions of uncertainty in economic, social, political processes. The article examines the role of revenues collected by customs authorities in the tax revenues of budgets of various groups of countries according to the classification of the World Customs Organization and their relationship with the level of economic development of such countries. The conducted research confirmed the important role of customs payments in the formation of the revenue base of the state budget of Ukraine (appr. 40% of total revenues). The most important fiscal role among customs payments is related to VAT on imported goods, while customs duty and excise tax on imported excise goods perform mainly a regulatory function, since their fiscal role is not significant. The positive and negative consequences of the use of customs payments as indirect taxes on different subjects of economic systems (governments, business and population) are studied. The negative economic results of the active use of indirect taxation include an increase in general prices level and an increase in consumer inflation. The high dependence of budget tax revenues on customs payments is a feature of countries with a low economic development level. It is necessary to create conditions for attracting investments, restoration of industrial and social infrastructure, reconstruction of housing, and production facilities in order to ensure the reliable basis for budget revenues col- lection. This kind of policy can contribute to the recovery of the economy, increasing businesses and population incomes, form- ing financial reserves, and will also create an economic base for a gradual increase in the role of direct taxes in budget revenues. Prevention of violations of custom legislation in foreign economic transactions can increase the revenues to the state budget without increasing the tax burden.
THE CONTRADICTORY IMPACT OF INSTITUTIONAL CHANGES ON THE ECONOMIC DEVELOPMENT OF THE EUROPEAN REGION COUNTRIES
Authors:   Taras Shevchenko National University of Kyiv, Zavazhenko Andrii
Published: September 2023

The article describes the contradictory impact of institutional changes on the economic development of the European region countries. The article’s topic is a relevant theoretical problem within the framework of research into the new institutional theory, as it substantiates ways of realizing the negative impact of inefficient institutions on the process of economic systems development. The theoretical basis of the convergence and divergence of the development trajectories of economic systems in the context of the implementation of institutional reform is analyzed. The author notes that the process of institutional changes is not uniform and its result can be both effective and ineffective institutions, which become the basis of divergent trajectories of the development of economic systems. As a result of the theoretical analysis, the author substantiated the hypothesis regarding the contradictory influence of institutional factors on the socio-economic development of economic systems. The key institutional factors that can influence economic development are described such as property rights defence, access to capital, human capital, level of corruption, social inequality, economic policy etc. According to the results of the conducted econometric analysis of institutional indicators of economic development of the European region countries that is based on statistical data from recent years, it was empirically established that there is a convergent-divergent influence of institutional factors on the economic development of the European region countries. It can be explained because the institutional environments of analyzed countries have unique development trajectories that reflect complex and other convergent-divergent processes when the accumulated elements of the system create an individual unique integrity that differs from country to country. The author also warns that the described directions of Ukraine’s institutional reforming should not be carried out as an exception but purposefully in the form of implementing a long-term strategy for reforming all areas of social life.
INNOVATIVE POWER AND STATUS OF THE UKRAINIAN ECONOMY
Authors:   Uzhorod National University, Zayats Olena , Yarema Tomash ,   Uzhorod National University, Chornomaz Mykola ,   Uzhorod National University
Published: September 2023

The innovative power of Ukraine plays a vital role in driving its economic growth and competitiveness, primarily as the country aims to integrate with Europe and works towards attaining candidate status for EU membership. To accurately assess Ukraine's innovative status and identify areas for improvement, it is imperative to evaluate critical indicators and factors. Given the current economic realities, pursuing an effective innovation policy for our country is of utmost importance, considering its status as a candidate for European Union membership. The article aims to analyze the innovative power and status of the Ukrainian economy within the framework of European integration processes. It has been determined that the level of innovative activity in Ukrainian companies is currently below the international standard and needs to catch up to the average benchmark set by the European Union. Emphasis is placed on the fact that most innovations are primarily "new to the firm," often achieved through equipment acquisition, rather than "new to the world" innovations. The study revealed that Ukrainian companies encounter a challenging external environment in their pursuit of innovation. Consequently, critical positive and negative factors that significantly influence the potential innovative power of the Ukrainian economy have been identified. The article analyzes the international legal agreements that serve as the foundation for cooperation between Ukraine and the EU in research and innovation. Furthermore, it highlights that Ukraine is classified as a new innovator according to the European Innovation Scoreboard 2022. The article emphasizes the structural disparities between Ukraine and the European Union, which significantly impact the innovative status and strength of the Ukrainian economy. The research concluded that Ukraine has substantial potential for cultivating an innovation-driven economy, owing to its large talent pool and entrepreneurial aptitude. Nevertheless, the innovative potential of Ukraine has yet to be fully realized, and the military conflicts on Ukrainian territory have introduced a new existential risk to the country's innovation sphere. Overcoming this challenge necessitates the effective engagement of public-private partnerships, a substantial increase in scientific funding within Ukraine, and the utilization of new opportunities, including financial ones, presented by the candidate status for EU membership. Particularly, joining the European research area holds promise in this regard.
TRANSFORMATION OF THE SYSTEM OF JOINT INVESTMENT INSTITUTIONS IN THE CONDITIONS OF GLOBAL CHALLENGES
Authors:   Taras Shevchenko National University of Kyiv, Kalnyi Serhii , Stepanova Alla ,   Taras Shevchenko National University of Kyiv
Published: September 2023

The paper provides comprehensive analysis of investment funds and their specific under economy transformation, supported by internationalization and globalization of economic systems. Main historical phases and milestones of investment funds development were outlined. Definition was provided to investment companies, as well as major organizational forms were defined on mechanisms to accumulate and distribute financial resources. Types of investment companies were classified. Specific of investment strategies was underlined on their impact on investment portfolio. Particular attention is paid to new forms and types of investment institutions, such as hedge funds and exchange-traded funds. The history of their formation and stages of development, including the specified features of their functioning and shortcomings of this type of institutes, are highlighted. The proposed periodization of the formation of joint investment institutes. The positive and negative impact of JII on interna- tional financial markets is determined. Important components of the article are the analysis of panel analytical data by years and countries of the world, provided to confirm the main theses, as well as the definition of the main trends in the development of joint investment institutions. The leading countries in terms of assets of joint investment institutes and the structural composition of open investment funds have been determined. Stock funds dominate, followed by bond funds. The assets of US investment funds and the financial assets of institutional investors and the GNI of the US for 2011–021 were analyzed. The regional struc- ture of investment funds was studied. US investment funds make up 56% of the global volume, European – 29.9%, together 85.9%. The structure of joint investment institutions was analyzed for the 3rd quarter of 2022. The main share of JII in the USA is made up of stock funds 48.2% (money market funds – 14.3%), in the EU this figure is 31.7% (money market funds – 8.1%). The dynamics of the growth of the assets of institutional investors in the USA is characterized, by a significant increase that has been revealed since 2019 in comparison with the period 2011–2017. The investment funds of the USA and Europe continue to play a decisive role in the joint investment market.
LA EVALUACIÓN DE LA SOLVENCIA DEL CONSUMIDOR FINANCIERO COMO MANIFESTACIÓN DE LA SEGURIDAD EN EL CONSUMO Y SU INCIDENCIA EN LA RESPONSABILIDAD CIVIL DEL PRESTAMISTA INCUMPLIDOR
Authors: Alarcón Cañuta Miguel
Published: September 2023

El trabajo analiza y reflexiona respecto de la responsabilidad civil que le cabe al prestamista en caso de incumplimiento de los deberes circunscritos a la evaluación de solvencia del art. 17 N de la LPDC. Para ello, estudia la naturaleza de los deberes establecidos en la norma en su vinculación con el deber de seguridad en el consumo y, a partir de allí, determina el régimen de responsabilidad civil aplicable al caso de incumplimiento, y los alcances que ello presenta en algunos elementos de la respectiva responsabilidad civil.
BASES PARA UN DERECHO CHILENO DEL ENRIQUECIMIENTO INJUSTIFICADO. HACIA EL ABANDONO DE UN ENFOQUE UNITARIO
Authors: Campos Micin Sebastián Nicolás
Published: September 2023

El presente artículo, luego de formular una crítica general a la aproximación predominante en la doctrina nacional en torno al enriquecimiento injustificado, realiza una reconstrucción esquemática del derecho del enriquecimiento injustificado y presenta una tipología de supuestos que dan o debiesen dar lugar a acciones restitutorias. Se identifican varios supuestos arquetípicos de enriquecimiento injustificado y se expone cuáles son las diferencias de las correspondientes acciones en lo que atañe a sus funciones, requisitos de procedencia y medidas restitutorias. Luego se delinea el régimen jurídico que el Código Civil chileno asocia a cada supuesto arquetípico. Finalmente, se propone abandonar el enfoque unitario que ha prevalecido en la doctrina nacional y transitar hacia un estudio de las particularidades de los supuestos arquetípicos de enriquecimiento injustificado, de modo que las hipótesis no reguladas se asimilen a las que sí lo están, aplicando a aquellos las reglas que resulten más adecuadas.
CONTRATO A LA PARTE ENTRE EL ARMADOR Y LA TRIPULACIÓN DE UNA EMBARCACIÓN DE PESCA ARTESANAL
Authors: Manterola Pablo
Published: September 2023

El trabajo analiza la sentencia recaída en un caso en que el armador y la tripulación de una embarcación de pesca artesanal celebraron lo que la Ley General de 345 Pesca y Acuicultura llama un “contrato o sociedad a la parte”. La tripulación de mandante ejerció la acción de cumplimiento de este contrato y solicita que el armador sea condenado a pagar el producto de una reliquidación de la pesca de varias temporadas, así como la parte que le correspondía en una venta de la cuota de captura a un tercero. El comentario pone de relieve las dificultades que plantea la distinción entre negocios parciarios y contrato de sociedad, así como el lugar (contingente) de la personalidad jurídica en este último.
ЕФЕКТИВНІСТЬ ВЗАЄМОДІЇ БАТЬКІВ ТА ДІТЕЙ ІЗ ПОРУШЕННЯМИ РОЗВИТКУ В УМОВАХ ІНКЛЮЗИВНО-РЕСУРСНОГО ЦЕНТРУ
Authors: Яковлева Світлана Дмитрівна
Published: September 2023

У статті розглядається питання взаємодії батьків дітей, які мають затримку психічного розвитку, та фахівців інклюзивно-ресурсного центру. Успіх та просування у розвитку дітей із відповідними порушеннями залежать від тісної, злагодженої роботи фахівців інклюзивно-ресурсного центру та батьків, а також їх активного включення як рівноправних членів команди психолого-педагогічного супроводу, що стало метою експерименту. Дослідження проводилося у закладах відповідної категорії дітей із труднощами у навчанні як найбільш чисельній категорії дітей із порушеннями у молодшому шкільному віці. Відвідування такими дітьми інклюзивно-ресурсного центру дає змогу реалізувати своє право на правильну діагностику та отримання якісної корекційної роботи. Методи дослідження. Визначався рівень задоволеності батьків дітей із порушеннями розвитку з роботою фахівців центру, а також робота за методиками «Вивчення задоволеності батьків роботою фахівців інклюзивно-ресурсного центру», «Вивчення оцінки батьками ролі інклюзивно-ресурсного центру у вихованні дітей із тяжкими мовленнєвими вадами» (розроблена доцентом А.А. Андрєєвим) та оцінювався рівень допомоги дитині з тяжкими мовленнєвими порушеннями. Стаття містить узагальнені результати дослідження з їх аналізом та висновками. Результати дослідження. Зазначено, що рівень задоволеності батьків роботою фахівців інклюзивно-ресурсного центру підвищився за умови їх тісної, тривалої співпраці, а також зросла оцінка допомоги, яку отримували діти з труднощами у навчанні. Це дало змогу отримати позитивні зрушення у розвитку та позитивні результати корекційно-виховного впливу на дану категорію вихованців. Усі фахівці інклюзивно-ресурсного центру усвідомлювали необхідність постійної тісної взаємодії з батьками дітей із порушеннями розвитку для отримання позитивного результату корекційно-розвиткової роботи, яка надається дітям в умовах спеціальної організації діяльності дітей в інклюзивно-ресурсному центрі. Конкретно доведено, що інклюзивно-ресурсний центр надає комплексний психолого-педагогічний супровід дитині із затримкою психічного розвитку, при цьому надає ефективні поради, інструкції, можна сказати, навчає батьків, включаючи їх в активну роботу зі своїми дітьми, а також мотивуючи фахівців інклюзивно-ресурсного центру до надання більш ефективного корекційно-розвиткового впливу. Висновки. Результати дослідження дають змогу зробити висновок: взаємодія батьків дітей із труднощами у навчанні та фахівців інклюзивно-ресурсного центру повинна являти собою особливу форму співпраці, яка передбачає активну участь у корекційно-розвивальному процесі, тісний зв'язок із фахівцями центру з метою компенсації порушень психічного розвитку дітей даної категорії.
Rheumatoid Arthritis and Periodontal Disease Association and Effect of Disease Modifying Anti-Rheumatic Drugs: A Narrative Review
Authors: Mohd Zamri Nuramalin Sofya , Taib Haslina , Wan Mohamad Wan Majdiah , Sabarudin Muhammad Annurdin
Published: September 2023

Associations between periodontal disease (PD) and other diseases, including rheumatoid arthritis (RA), respiratory disease, and chronic kidney disease, have been reported. Patients with moderate to severe periodontitis have a high risk of suffering from RA and vice versa. This bidirectional relationship could be due to genetic (HLA-DR), dysregulation of the inflammatory response, and the role of Porphyromonas gingivalis (P. gingivalis), which stimulates anti-cyclic citrullinated peptide antibodies via citrullination. This review aims to identify associated factors that contribute to RA and PD relationship and to explore the effects of disease-modifying anti-rheumatic drugs (DMARDs) on PD. A literature search was performed using PubMed and Google Scholar to identify related articles published from the year 1990 to 2020 within the research interest using keyword combinations. Thirty-one articles that fit the research interest and address the research questions for both objectives were selected. As a result, the associated factors for RA and PD relationship, including genetic predisposition, immunoregulatory imbalance, and the role of P. gingivalis in the citrullination process as a risk factor of RA. Significant improvement was found in periodontal parameters in RA patients treated with biologic and synthetic DMARDs. This review reported common factors contributing to the RA and PD relationship and the benefits of DMARDs on periodontitis.
Áhrif undirbúnings á gæði táknmálstúlkunar
Authors: Þóroddsdóttir Hólmfríður , Gísladóttir Karen Rut
Published: September 2023

Greinin sem hér birtist fjallar um táknmálstúlkun og áhrif undirbúnings á hugrænt álag túlka og tengsl þess við gæði táknmálstúlkunar. Þátttakendur í rannsókninni voru starfandi táknmálstúlkar á Íslandi. Rannsóknin var unnin með blönduðum rannsóknaraðferðum, þar sem tekin voru viðtöl við táknmálstúlka og send út spurningakönnun í tengslum við sérstök túlkaverkefni, auk þess sem hluti þátttakenda tók þátt í sérhönnuðu túlkunarprófi. Prófið var framkvæmt til að ná fram tölfræðilegum upplýsingum um áhrif undirbúnings á táknmálstúlkun og fá túlkana sjálfa til að lýsa undirbúningi sínum og greina þætti sem mikilvægt er að undirbúa fyrir túlkun.

Niðurstöður rannsóknarinnar varpa ljósi á að undirbúningur bæði eykur skilning túlkanna á umræðuefninu sem túlka á og auðveldar þeim framsetningu túlkunarinnar. Þessi atriði draga úr hugrænu álagi og auka gæði túlkunar. Tölfræðilegar upplýsingar sýndu að í óundirbúnum túlkunum töpuðust tæp 20% þeirra aðalatriða sem átti að túlka, en einungis um 10% í undirbúnum túlkunum. Niðurstöður benda til þess að mikilvægt sé að táknmálstúlkar hafi tækifæri til að undirbúa sig fyrir verkefni sín. Til að tryggja gæði túlkunar ætti það að vera hagsmunamál allra túlkanotenda að túlkar fái þann undirbúning sem þeir þurfa.
Generational differences in communication and translation to medical education
Authors: Jimenez Shannon , Ford-Wilcox Haley
Published: September 2023

Context: Each generation has special characteristics brought out by the times in which they have lived, which have affected the way they communicate in both reception and expression of information.

Objectives: This article looks at key differences between the generations and discusses their application to medical education. Both older generations, as well as younger generations, will be discussed.

Methods: The initial research for this review was started in March 2020 as part of a preceptor podcast series. Both listed authors participated in the literature search and assimilation. Articles reviewed came from various resources included the Pew Institute, marketing or communication companies, and universities.

Results: This article outlines many differences as well as some similarities between the 5 unique working generations. Some of these characteristics include stoicism, altruism, idealism and beneficence.

Conclusions: Keeping these typical characteristics in mind, however, when interacting with members of these generations can improve communication all around. In medical education, improved communication can facilitate better learning and more productive and pleasant experiences for the teacher and the learner.
Determination of amygdalin in fifteen different fruit kernels and extraction optimization
Authors:   Marmara University, Institute of Health Science, 34854, Maltepe, Istanbul, Turkey, OZTURK Busra Nagihan , AYAZ SEYHAN Serap ,   Marmara University, Faculty of Pharmacy, Department of Analytical Chemistry 34854,     Basıbuyuk, Istanbul, Turkey, BILGIC ALKAYA Dilek ,   Marmara University, Faculty of Pharmacy, Department of Analytical Chemistry 34854,     Basıbuyuk, Istanbul, Turkey
Published: September 2023

Amygdalin (AMG) is mainly as an alternative therapy for traditional cancer treatment. In this study, an effective HPLC-DAD method was developed to investigate the extraction efficiency and determine AMG levels in fifteen fruit kernels belonging to different families. AMG in bitter almond was extracted from using various solvents by different extraction methods (Soxhlet, ultrasonic, orbital shaking and microwave extraction). The most suitable method was determined by the optimized HPLC-DAD method was applied to fifteen different fruit kernels. The recoveries were in the range 94.68% to 95.26%. The LOD and LOQ values were 0.0097 mg/g and 0.0295 mg/g, respectively. The amygdalin content in kernel fruits was determined ranging from 0.074 to 65.21 mg/g. This study showed that AMG was determined in a short time and with high yield, and the presence of AMG was proven in other fruit kernels belonging to different families that had not been proven before.
Zn(OAc)2•2H2O-catalyzed green synthesis of substituted 1-amido/thioamidoalkyl-2-naphthols
Authors:   Nagnath Arts, Commerce and Science College, Aundha Nagnath, Hingoli-431705, Maharashtra, India, TOTAWAR Pradeep Rameshrao , VARALA Ravi ,   Scrips Pharma, Hyderabad-500 076, Telangana, India, PULLE Jitendra S. ,   Shri Guru Buddhi Swami Mahavidyalaya, Purna, Parbhani-431511, Maharashtra, India
Published: September 2023

Zn(OAc)2.2H2O (5 mol%)-catalyzed one-pot multicomponent reaction of β-napthol, aldehydes and amide/thioamides to produce corresponding amidobenzylnaphthols in shorter reaction times (20 min-2 h) under neat conditions at 70 oC, is reported in good to excellent yields (58-95%).
Resistencia a la insulina: sustrato fisiopatológico del síndrome metabólico
Authors: García Mendoza María Victoria , Garcés Paredes Eder , Pazmiño Moya Shaaron Magaly , Prado Mendoza Jean Pierre , Moreira Pincay Marieta Stefania
Published: September 2023

Introducción: La resistencia a la insulina es una condición médica caracterizada por disminución de la respuesta tisular a la insulina; o una disminución en su producción o calidad, lo que se traduce en aumento consecuente de la concentración de glucosa en sangre; el síndrome metabólico constituye una patología mediada por la insulinorresistencia y abarca la coexistencia de diabetes tipo 2, hipertensión arterial, dislipemia, obesidad central. Objetivo: Sintetizar los actuales conocimientos respecto a la fisiopatología del síndrome metabólico y el rol de la insulinorresistencia. Metodología: Se trata de una revisión narrativa de la literatura que se construye a partir de artículos originales, revisiones sitemáticas y narrativas publicadas en Pubmed, ScienceDirect, Redalyc, y SciELO, empleando los descriptores y términos: síndrome metabólico, resistencia a la insulina, celulas secretoras de insulina. La selección se realizó según los criterios de inclusión: tiempo de publicación menor a 10 años, idioma inglés y/o español y encontrarse disponible de forma libre en su versión completa. Conclusión: La insulinorresistencia constituye un fenómeno fisiopatológico complejo que, a diferencia del clásico y erroneo concepto glucocentrico, impacta sobre el metabolismo de los glucidos, lípidos y proteínas, afectando en consecuencia a todos los niveles funcionales y estructurales del organismo, constituyendo el sustrato fisiopatológico en el desarrollo del síndrome metabólico.
Materiales metálicos: Revisión del estado del arte
Authors: Verdezoto Espinoza Edison Miguel , Rosero Ruano Leani Jasmin , Balla Yucailla John Danny , Valiente Sigcha Antony Adrian
Published: September 2023

Introducción: Los materiales metálicos han utilizado durante muchos años, en una diversa gama de aplicaciones a nivel industrial, esto debido a que poseen excelentes propiedades físicas y mecánicas. Los materiales metálicos son elementos producidos mediante varios cambios de manufactura, para desarrollar aleaciones con mejores propiedades, como mayor resistencia y tenacidad. En la industria, es importante conocer los procesos que se encuentran en disposición para la selección de una mejor opción y optimización en el consumo del material, así obteniendo un aumento en la eficiencia de la producción. Metodología: Este artículo indaga los avances de los materiales metálicos y su relevancia en la industria actual, analizando sus características químicas y mecánicas, y su influencia en diversas aplicaciones en sus aleaciones con compuestos de Hierro-Carbono, a bajas conductividad con distintos elementos en su composición. Resultados: Se resalta la importancia de mantenerse informado en este campo para utilizar al máximo las ventajas que ofrecen estos materiales en un entorno industrial competitivo. Es fundamental chequear investigaciones previas y estudios científicos para la mejor comprensión de los materiales metálicos, así como presentar ejemplos de aplicaciones industriales para resaltar sus beneficios y desafíos. El entendimiento de los procesos de manufactura y la elección adecuada de materiales son elementos importantes para mejorar la eficiencia y reducir el desecho de recursos en la producción industrial. Conclusión: los materiales metálicos continúan siendo esenciales para la industria debido a sus propiedades avanzadas y su capacidad para satisfacer diversas necesidades de aplicación. Área de estudio general: ciencia de los materiales, Área de estudio específica: resistencia de los materiales, Tipo de estudio: revisión bibliográfica.
Analytical performance of the FDA-cleared Parsortix® PC1 system
Authors: Templeman Amy , Miller M. Craig , Cooke Martin J. , O'Shannessy Daniel J. , Gurung Yuwaraj , Pereira Tiago , Peters Samuel G. , De Piano Mario , Teo Manilyn , Khazan Negar , Kim Kyukwang , Cohen Evan , Lopez Heather B. , Alvarez Franklin , Ciccioli Mariacristina , Pailhes-Jimenez Anne-Sophie
Published: September 2023

Introduction: The Parsortix® PC1 system, Food and Drug Administration (FDA) cleared for use in metastatic breast cancer (MBC) patients, is an epitope-independent microfluidic device for the capture and harvest of circulating tumor cells from whole blood based on cell size and deformability. This report details the analytical characterization of linearity, detection limit, precision, and reproducibility for this device.
Methods: System performance was determined using K2-EDTA blood samples collected from self-declared healthy female volunteers (HVs) and MBC patients spiked with prelabeled cultured breast cancer cell lines (SKBR3, MCF7, or Hs578T). Samples were processed on Parsortix® PC1 systems and captured cells were harvested and enumerated.
Results: The system captured and harvested live SKBR3, MCF7, and Hs578T cells and fixed SKBR3 cells linearly between 2 and ~100 cells, with average harvest rates of 69%, 73%, 79%, and 90%, respectively. To harvest ≥1 cell ≥95% of the time, the system required 3, 5 or 4 live SKBR3, MCF7 or Hs578T cells, respectively. Average harvest rates from precision studies using 5, 10, and ~50 live cells spiked into blood for each cell line ranged from 63.5% to 76.2%, with repeatability and reproducibility percent coefficient of variation (%CV) estimates ranging from 12.3% to 32.4% and 13.3% to 34.1%, respectively. Average harvest rates using ~20 fixed SKBR3 cells spiked into HV and MBC patient blood samples were 75.0% ± 16.1% (%CV = 22.3%) and 68.4% ± 14.3% (%CV = 21.1%), respectively.
Conclusions: These evaluations demonstrate the Parsortix® PC1 system linearly and reproducibly harvests tumor cells from blood over a range of 1 to ~100 cells.
GERAKAN BERSIH MUSHOLLA (GBM) OPTIMALISASI FASILITAS MUSHOLLA DI DESA SUMBERURIP
Authors: Amalia Ayu , Asmara Dwi Aksa Yudha , Putra Purnama
Published: September 2023

Community service is a forum that students can use to implement the knowledge gained during lectures. This service was carried out in Sumberurip village, Pebayuran sub-district, Bekasi district, with a prayer room cleaning program in Sumberurip village. Cleanliness is very important in Islam. Because a clean environment will create a comfortable and healthy place. The condition of a dirty prayer room will make a person not solemn in worship and can be a place that has the potential to cause disease. In this community service, the author carries out a community service program to clean the prayer room so that everyone can worship solemnly. Community service activities related to the clean prayer room movement apply community education and training methods to three prayer rooms in Sumberurip village. The target of this activity is the surrounding community with the assistance of Unisma Bekasi students. The success of the community service activities is the clean condition of the prayer room environment in Sumberurip village, increasing public awareness of the importance of cleanliness of places of worship and the surrounding environment, and strengthening a sense of shared responsibility in caring for and maintaining places of worship.
PELATIHAN SISTEM ADMINISTRASI PENDATAAN PENDUDUK MELALUI WEBSITE PRODESKEL DESA SINDANGSARI KABUPATEN BEKASI
Authors: Farhana Firda , Muis Abdul , Rofieq Ainur
Published: September 2023

The processing of population data in regional offices must be regulated and detailed in detail. This is very important because accurate population data collection in Indonesia starts from accurate village data. Population administration system training activities through the website prodeskal singosari village implemented as a form of real paper Lecture activities for community service. The purpose of this training is to assist and facilitate village employees in the process of population data collection and improve services to the community. The method used is training, the activities of which are carried out through several stages. Preparation phase, implementation phase and evaluation phase, this training is needed by village employees, especially to improve population administration services. An indicator of the success of the training is the increasing knowledge and skills of village employees in managing the population administration of sindangsari village.
SOSIALISASI OLAHRAGA TRADISIONAL HADANGAN DI DESA KERTAJAYA
Authors: Lengari Servasius Loise , Abidin Dindin , Faiz Ridlo Azi
Published: September 2023

Community service activities related to the socialization of traditional hadang sports aim to provide understanding and insight into the culture of hadang traditional sports. The target audience for this community service activity are students in Kertajaya Village, Pebayuran District, Bekasi Regency. The method of implementing community service applies community education methods in the form of socialization of the hadang game which then practices the implementation of the hadang game method to students. This community service activity has had a good impact, namely increasing understanding of traditional hadang games among students, increasing knowledge of traditional sports and cultural heritage, increasing the development of motor skills, creativity, emotional intelligence, social interaction and concentration, and promoting a healthy lifestyle and appreciation of traditional sport.
PELATIHAN PEMBUATAN DAN PENGADAAN BIOPORI SEDERHANA SEBAGAI SOLUSI DRAINASE DI DESA JAYALAKSANA
Authors: Wahhid Willdan , Dian Eka Fatimah , Supratno Setyo
Published: September 2023

The accumulation of silt and grass in the neighborhood around residents' homes and around the drainage channels is one of the factors that hinders water from flowing into the river, causing overflow at several points. Knowledge on how to make and manage biopori is still not widespread, especially among rural communities. Training on the manufacture and procurement of simple biopores as a drainage solution is expected to make a positive contribution to the community's quality of life, the environment, and overall sustainability. This service applies a combination of methods in the form of science and technology diffusion and training to the people of Dea Jayalaksana, Bekasi Regency. The impact of the success of this program is improving local drainage thereby reducing the risk of flooding, soil erosion and environmental pollution in Jayalaksana Village.
PENGGAGASAN PEMBENTUKAN WADAH KOMUNIKASI PENGURUS MASJID DI DESA SUMBERSARI
Authors: Nasution Maulana Muhammad Azhar , Siaga Pangestuti Rinda , Rusham Rusham
Published: September 2023

The aim of establishing a communication forum for mosque administrators is to increase Islamic ukhuwah, increase the potential and function of mosques, increase the potential and empowerment of Muslims in the economic, social and community sectors, as well as realize local collaboration programs between mosques. The method of implementing service activities will involve a series of strategic steps. The method of implementing community service activities applies the socialization method through Forum Group Discussion (FGD) to mosque administrators. The impact of this success was in the form of the formation of a communication forum for mosque administrators in Sumbersari Village under the name IMAM (Association of Mosques and Mushollas), increased communication between fellow mosque and musholla administrators.
PELATIHAN CALISTUNG SEBAGAI UPAYA PEMBERANTASAN BUTA AKSARA BAGI WARGA DESA PANTAI BAKTI
Authors: Azzizah Nimah Anis , Mulyadi Acep , Irham Irham
Published: September 2023

This community service discusses calistung as an effort to eradicate illiteracy for the residents of Pantai Bakti Village. Calistung is an activity that includes several abilities, namely the ability to read, write and count. The ability to read, write and count is very important for a person from an early age to old age. With the ability to read, write and count a person is able to learn knowledge and obtain information. Therefore, failure to master this skill would result in serious trouble. Pantai Bakti Village is a village where there are still residents who cannot read, write and count, this is due to dropping out of elementary school, family economic difficulties and parents who do not care about education. This activity is one of the KKN work programs, with this activity it will improve the quality of human resources for residents in Pantai Bakti Village. This activity was carried out at the Jamie Baitul Mu'minin mosque for three days. The method used was training through tutoring. This training can improve the ability of the residents of Pantai Bakti Village in reading, writing and arithmetic.
SOSIALISASI PENCEGAHAN STUNTING UNTUK ANAK BALITA DI DESA BANTARJAYA
Authors: Shofa Ghefira Zahira , Mulyanti Kurniawati , Nadhira Qintharah Yuha
Published: September 2023

Nutritional problems are global problems that have a systemic impact on developing countries, including Indonesia. The problems that occur in malnourished children are not only in body posture, but have an impact on health both now and in the next life. Lack of outreach to parents regarding children's nutritional patterns is still a problem that must be addressed. The purpose of implementing community service related to the socialization of stunting prevention is to increase understanding regarding nutrition and child nutrition so that stunting can be prevented. The service method applies socialization and counseling to the target location of Bantarjay Village. The results of the service show that a positive role is in the form of increasing parental understanding regarding stunting prevention, good and nutritious eating patterns, and increasing in-depth understanding of how nutrition affects growth and development.
MEMBANGUN PERSONAL BRANDING PADA WARGA DESA BANTARSARI
Authors: Sayidah Hilda , Sulastri Tuti , Nadhira Qintharah Yuha
Published: September 2023

The Branding is common in the world of marketing. Branding is done to differentiate between a product and other products so as to bring out its distinctive characteristics. As it develops, the branding context has added to many lines, including in one's self-development. The flow of personal branding in the current digital era is very important to apply, especially for teenagers. The purpose of carrying out this service activity is to embody the perspective of adolescents in defining who they are. This is necessary because self-extension is a fundamental thing that must exist in a person, including teenagers. In forming this personal branding, it is conveyed through the socialization method, you can practice it so that teenagers in this activity can know and tame themselves more positively. As a result of this activity, the audience is able to create and practice personal branding for themselves, improve communication skills and expertise, in this case make up beauty, so that it becomes a business opportunity.
A CRITICAL REVIEW ON TECHNICAL OPERATION AND REDUCING HUMAN ERRORS
Authors: Chatterjee Prof. (Dr.) Subhasish , Banerjee Dr. Ranjita , Halder Prof. (Dr.) Biplab ,   ICFAI University
Published: September 2023

Human errors may occur everywhere and have a variety of consequences. Errors may occur as a result of pressures and situations in industrial operations and maintenance. If the prediction is inaccurate, the forecaster may die. Human error can be said to be a deliberate and voluntary action by a human interacting with another system that exceeds established tolerances defined by that system. The damages done through human error encompasses a continuum that runs from no injury or loss to major damage and casualties, including fatal accidents or death, at times. Blaming someone else often merely moves the individuals back to the setting where the error was made. Unless and until the reasons for square measurement mistakes are identified and corrected, the issue may exist indefinitely. This research looked at human errors in engineering operations. The action to be taken by the human involves the cognitive ability to decide between alternate courses of action based upon knowledge, skills, competencies, experience, and the combined external and internal inputs available to the human. The authors of this paper have made an attempt to do a review on human error in the context of engineering operations.
Hansen’s Disease with Pure Nerve Involvement and Perineural Abscess Mistaken for Peripheral Nerve Sheath Tumour
Authors: Sultan Moinuddin , Choudhary Mitali , Siddique Mazain , Lavhale Nihal , Vikram Badhe Padma
Published: September 2023

Nerve abscess is an infrequently reported complication of leprosy. It is also an uncommon first manifestation of leprosy. In this case, due to the absence of classic signs and symptoms, such as skin lesions, hypoesthesia, and loss of sensation, the swelling was clinically diagnosed as a peripheral nerve sheath tumour on initial presentation. The authors have described an unusual presentation of pure neuritic leprosy that showcased nerve abscess. Clinical presentation was swelling over the medial aspect of the right arm and ulnar aspect of the right forearm, and clawing of the fourth and fifth digits of the right hand, with no signs of inflammation present on the skin surrounding the swelling. Hansen’s disease with pure nerve involvement could not be considered as a differential diagnosis solely based on clinical examination, therefore posing a diagnostic challenge. On ultrasonography, the right ulnar nerve showed diffuse intermittent thickening and a heterogeneously hypoechoic fusiform area with internal echoes at the site of swelling indicating a nerve abscess. These led the authors to the diagnosis of leprosy with perineuronal abscess. Histopathology confirmed the diagnosis by revealing granulomas and acid-fast Hansen’s bacilli. The patient showed dramatic response to surgery, multidrug therapy, and systemic corticosteroids.
Menopoz Eş Desteği Ölçeği’ni Türkçe’ye Uyarlama Çalışması: Menopozda Eş Desteği
Authors: TESKERECİ Gamze , SÜMEN Adem
Published: September 2023

Amaç: Bu çalışma, Menopoz Eş Desteği Ölçeği’nin (MEDÖ) Türk kültüründe geçerlik ve güvenirliğini test etmek amacıyla yapılmıştır.

Gereç ve Yöntemler: Çalışma metodolojik tipte gerçekleşmiştir. Araştırmada olasılıksız örnekleme yöntemlerinden amaçlı örnekleme yöntemi kullanılmıştır. Çalışmaya Türkiye’nin güneyinde yer alan bir ilçedeki 45-65 yaş arası toplam 335 kadın katılmıştır. Araştırma verileri Kişisel Bilgi Formu ve Menopoz Eş Desteği Ölçeği kullanılarak, yüz yüze toplanmıştır. MEDÖ’nün psikometrik özelliklerini tespit etmek için kapsam ve yapı geçerliği ve iç tutarlık güvenirliği analiz yöntemlerinden yararlanılmıştır.

Bulgular: MEDÖ’nün 17 maddelik Türkçe formuna uygulanan açıklayıcı faktör analizi sonucuna göre dört boyutlu olduğu doğrulanmıştır. Faktör yükleri 0,553-0,881 arasında değişmektedir. Doğrulayıcı faktör analizine göre modelin, CFI, NFI değerleri bakımından iyi uyuma; χ2/sd, GFI, TLI, RMSEA değerleri bakımından kabul edilebilir uyuma sahip olduğu görülmüştür. Ölçeğin tümü için Cronbach Alfa katsayısı toplamda 0,958, alt boyutlarında ise 0,844-0,927 olarak bulunmuştur. Katılımcıların MEDÖ toplam puan ortalaması 102,03±37,54 ve ölçek alt boyut puanları arasındaki pearson korelasyon katsayısı 0,534-0,850 arasındadır.

Sonuç: Türk kültürüne uyarlanan MEDÖ menopozdaki kadınların eş desteğini belirlemede geçerli ve güvenilir bir ölçme aracıdır. Ölçek, hemşireler ve diğer sağlık hizmeti sunucuları tarafından birinci veya ikinci basamak sağlık hizmetlerinde, toplum çalışmalarında, menopoz dönemindeki kadınlara yönelik müdahale programlarında, bilimsel araştırmalarda ve eşten hangi tür destekleyici davranışların gerekli olduğunu belirlemede kullanılabilir.
Besin Ögesi Yoğunluğuna Genel Bakış
Authors: PINARLI Çağla , KARAAĞAÇ Rabia Melda
Published: September 2023

Besin ögesi yoğunluğu, sağladığı enerjiden daha fazla besin ögesi içeren besinleri tanımlamak için kullanılmaktadır. Diyetteki enerji yoğunluğu ile besin ögesi yoğunluğu ters orantılıdır. Diyetteki enerji yoğunluğunun azaltılması, vücut ağırlığı yönetimi veya genel sağlığın korunması amacıyla da olsa, besin ögesi yoğunluğunun artmasıyla sonuçlanmaktadır. Besin ögesi yoğunluğu ölçümleri, besin ögesi örüntü profillemelerine dayanmaktadır. Yüksek gelir düzeyine sahip ve gelişmiş ülkelerde besin ögesi örüntü profili modelleri; besin etiketleme, yasaların düzenlenmesi ve vergilerin düzenlenmesi için bilimsel gerekçe sağlamaktadır. Ayrıca besin ögesi yoğunluğu, demir eksikliği anemisi, sarkopeni, malnütrisyon, metabolik sendrom ve çalışma kapasitesi (üretkenlik) ile yakından ilişkili olarak görülmektedir. Besin ögesi yoğunluğu kavramı, aynı zamanda sürdürülebilir bir yaşam için de büyük öneme sahiptir. Dünya nüfusunun 2050 yılına kadar 10 milyara ulaşacağı tahmin edilmektedir. Herkes için yeterli besin ögesine sahip bir diyet sağlarken aynı zamanda gezegen refahını korumanın küresel bir sorun haline geleceği düşünülmektedir. Bu noktada sürdürülebilir beslenme ve sürdürülebilir gıda sistemleri ön plana çıkmaktadır. Araştırmalar, besin ögesi yoğunluğu yüksek olan besinlerin, çevre üzerine de daha olumlu etkileri olduğunu göstermektedir. Tüm bu nedenlerle, besin ögesi yoğunluğu kavramına, beslenme rehberleri ve diyet modelleri içerisinde daha fazla vurgu yapılması gerektiği düşünülmektedir.