bluuebunny/crossref_metadata_2025 huggingface dataset:
Association Between Plasma Metabolites and Psychometric Scores Among Children With Developmental Disabilities: Investigating Sex-Differences
Authors: Sotelo-Orozco Jennie , Abbeduto Leonard , Hertz-Picciotto Irva , Slupsky Carolyn M.
Published: December 2020

Background:Developmental disabilities are defined by delays in learning, language, and behavior, yet growing evidence has revealed disturbances in metabolic systems that may also be present. Little is known about whether these metabolic issues contribute to the symptoms or severity of these disabilities, or whether sex plays a role in these associations, given that boys are disproportionately affected by some developmental disabilities. Here we sought to investigate the correlation between psychometric scores, sex, and the plasma metabolome.

Methods:The plasma metabolomes of children with autism spectrum disorder (ASD;n= 167), idiopathic developmental delay (i-DD;n= 51), Down syndrome (DS;n= 31), and typically developing controls (TD;n= 193) were investigated using NMR spectroscopy. Spearman rank correlations and multiple linear regression models (adjusted for child's neurodevelopmental diagnosis, child's sex, child's age, child's race/ethnicity, maternal age at child's birth, and parental homeownership) were used to examine the association between plasma metabolites and sex in relation to psychometric measures of cognitive skills, adaptive behavior, and maladaptive behavior in our study population.

Results:Higher levels of metabolites involved in cellular energy and mitochondrial function among children with ASD (fumarate and cis-aconitate), DS (lactate), and TD (pyruvate) are associated with poorer cognitive and adaptive subscales. Similarly, higher o-acetylcarnitine associated with deficits in cognitive subscales among all DS cases and TD boys, and carnitine correlated with increased maladaptive behavior among girls with ASD and girls with DS. Among children with DS, elevated myo-inositol, ornithine, and creatine correlated with poorer scores across several subscales. Even among TD cases, elevated 3-hydroxybutyrate correlated with decreased receptive language. In contrast, higher levels of glutamate were associated with better socialization skills among ASD cases. Even after adjusting for the child's neurodevelopmental diagnosis, sex, and other possible confounders, key metabolites including glycolysis metabolites (lactate and pyruvate), ketone bodies (3-hydroxybutyrate and acetoacetate), TCA cycle metabolites (cis-aconitate and fumarate), as well as ornithine were associated with deficits in multiple domains of cognitive function, adaptive skills, and aberrant behaviors.

Conclusions:Our results highlight that some plasma metabolites may relate to specific functional subdomains within cognitive, adaptive, and behavioral development with some variation by diagnosis and sex.
Real-Time Estimation of Rt for Supporting Public-Health Policies Against COVID-19
Authors: Contreras Sebastián , Villavicencio H. Andrés , Medina-Ortiz David , Saavedra Claudia P. , Olivera-Nappa Álvaro
Published: December 2020

In the absence of a consensus protocol to slow down the spread of SARS-CoV-2, policymakers need real-time indicators to support decisions in public health matters. The Effective Reproduction Number (Rt) represents the number of secondary infections generated per each case and can be dramatically modified by applying effective interventions. However, current methodologies to calculate Rt from data remain somewhat cumbersome, thus raising a barrier between its timely calculation and application by policymakers. In this work, we provide a simple mathematical formulation for obtaining the effective reproduction number in real-time using only and directly daily official case reports, obtained by modifying the equations describing the viral spread. We numerically explore the accuracy and limitations of the proposed methodology, which was demonstrated to provide accurate, timely, and intuitive results. We illustrate the use of our methodology to study the evolution of the pandemic in different iconic countries, and to assess the efficacy and promptness of different public health interventions.
OpenVirtualObjects: An Open Set of Standardized and Validated 3D Household Objects for Virtual Reality-Based Research, Assessment, and Therapy
Authors: Tromp Johanne , Klotzsche Felix , Krohn Stephan , Akbal Mert , Pohl Leonardo , Quinque Eva M. , Belger Julia , Villringer Arno , Gaebler Michael
Published: December 2020

Virtual reality (VR) technology provides clinicians, therapists, and researchers with new opportunities to observe, assess, and train behavior in realistic yet well-controlled environments. However, VR also comes with a number of challenges. For example, compared to more abstract experiments and tests on 2D computer screens, VR-based tasks are more complex to create, which can make it more expensive and time-consuming. One way to overcome these challenges is to create, standardize, and validate VR content and to make it openly available for researchers and clinicians. Here we introduce the OpenVirtualObjects (OVO), a set of 124 realistic 3D household objects that people encounter and use in their everyday lives. The objects were rated by 34 younger and 25 older adults for recognizability, familiarity, details (i.e., visual complexity), contact, and usage (i.e., frequency of usage in daily life). All participants also named and categorized the objects. We provide the data and the experiment- and analysis code online. With OVO, we hope to facilitate VR-based research and clinical applications. Easy and free availability of standardized and validated 3D objects can support systematic VR-based studies and the development of VR-based diagnostics and therapeutic tools.
The Winter Habitat Selection of Red Deer (Cervus elaphus) Based on a Multi-Scale Model
Authors: Sun Yue , Yu Yanze , Guo Jinhao , Zhang Minghai
Published: December 2020

Single-scale frameworks are often used to analyze the habitat selections of species. Research on habitat selection can be significantly improved using multi-scale models that enable greater in-depth analyses of the scale dependence between species and specific environmental factors. In this study, the winter habitat selection of red deer in the Gogostaihanwula Nature Reserve, Inner Mongolia, was studied using a multi-scale model. Each selected covariate was included in multi-scale models at their “characteristic scale”, and we used an all subsets approach and model selection framework to assess habitat selection. The results showed that: (1) Univariate logistic regression analysis showed that the response scale of red deer to environmental factors was different among different covariate. The optimal scale of the single covariate was 800–3200 m, slope (SLP), altitude (ELE), and ratio of deciduous broad-leaved forests were 800 m in large scale, except that the farmland ratio was 200 m in fine scale. The optimal scale of road density and grassland ratio is both 1600 m, and the optimal scale of net forest production capacity is 3200 m; (2) distance to forest edges, distance to cement roads, distance to villages, altitude, distance to all road, and slope of the region were the most important factors affecting winter habitat selection. The outcomes of this study indicate that future studies on the effectiveness of habitat selections will benefit from multi-scale models. In addition to increasing interpretive and predictive capabilities, multi-scale habitat selection models enhance our understanding of how species respond to their environments and contribute to the formulation of effective conservation and management strategies for ungulata.
Enhancement of Live Food Nutritional Status with Essential Nutrients for Improving Aquatic Animal Health: A Review
Authors: Samat Nur Amalina , Yusoff Fatimah Md , Rasdi Nadiah W. , Karim Murni
Published: December 2020

At the present time, no artificial larval diet is capable of entirely fulfilling the dietary requirements of several larval fish and crustacean species. Zooplankton live food is the basic foundation of fish larviculture, and successful rearing of fish larvae still heavily depends on an adequate supply of nutritious live food. Despite being important, the production protocols of copepods and cladocerans (Moina) are still underdeveloped in hatcheries. Rotifers and Artemia are the most commonly used live foods. However, these live foods are evidently lacking in crucial nutrient constituents. Hence, through nutrient enrichment, live food with the nutritional profile that meets the requirements of fish larvae can be produced. With the aim to maximize the effectiveness of production to optimize profitability, it is important to evaluate and improve culture techniques for the delivery of micro- and macro-nutrients as feed supplements to larvae in aquaculture systems. Bioencapsulation and enrichment are the evolving techniques in aquaculture that are commonly employed to enhance the nutritional quality of live food by integrating nutrients into them, which subsequently improves the growth, survival, and disease resistance of the consuming hosts. This review aims to highlight some of the approaches and methods used to improve the nutritional quality of live food by modifying their nutrient composition, which could have immense promise in the enhancement of aquatic animal health.
Impact of the First COVID-19 Lockdown on Management of Pet Dogs in the UK
Authors: Christley Robert M. , Murray Jane K. , Anderson Katharine L. , Buckland Emma L. , Casey Rachel A. , Harvey Naomi D. , Harris Lauren , Holland Katrina E. , McMillan Kirsten M. , Mead Rebecca , Owczarczak-Garstecka Sara C. , Upjohn Melissa M.
Published: December 2020

Initial COVID-19 lockdown restrictions in the United Kingdom (23 March–12 May 2020) prompted lifestyle changes for many people. We explored the impact of this lockdown phase on pet dogs using an online survey completed by 6004 dog owners, who provided information including dog management data for the 7 days prior to survey completion (4–12 May 2020), and for February 2020 (pre-lockdown). We explored associations between potential predictors and four outcomes relating to changes pre-/during lockdown (reduction in number and duration of walks; increased frequency of play/training, and provision of toys). Most owners (79.5%) reported their dog’s routine had changed compared to pre-lockdown. There was a four-fold increase in the proportion not left alone for >5 min on any day during a weekly period (14.6% pre-lockdown, 58.0% during lockdown), with the proportion being left for ≥3 h at a time decreasing from 48.5% to 5.4%. Dogs were walked less often and for less time daily during lockdown, with factors related to the dog, owner, household, and home location associated with changes to walking practices. Many dogs had more play/training sessions and were given toys more frequently during lockdown. Decreased walk duration was associated with increased odds of play/training opportunities and toy provision. These changes to dog management have the potential for immediate and longer-term welfare problems.
Scattering or Pushing for Object Singulation in Cluttered Environment: Case Study with Soma Cube
Authors: Khan Muhammad Umair Ahmad , Imran Abid , Kim Sanghwa , Hwang Hyunho , Lee Ji Yeong , Lee Sungon , Yi Byung-Ju
Published: December 2020

This paper proposes a hybrid singulation approach combining dynamic scattering and pushing techniques. Using the impulse-based dynamic model, a guideline is provided to decide whether scattering or pushing is conducted for object singulation. The Soma cube consisting of seven blocks is used as the test example. The target is to singulate all the blocks. The dynamic scattering technique was initially applied to separate blocks in the formation. However, scattering alone does not provide target singulation in all the cases. So we combine the quasi-static pushing technique to complete the singulation of all the blocks. In pushing, image segmentation based on principal component analysis (PCA) algorithm was employed to singulate multiple blocks in clutter and prehensile manipulation was used to remove isolated blocks. Several 2-D formations of the Soma cube are used as the test cases. To validate the effectiveness of our approach, we have conducted comparative analysis which clearly shows that the hybrid singulation achieves singulation in much less time as compared to the pure pushing approach.
Molecular MR Imaging of Prostate Cancer
Authors: Kader Avan , Brangsch Julia , Kaufmann Jan O. , Zhao Jing , Mangarova Dilyana B. , Moeckel Jana , Adams Lisa C. , Sack Ingolf , Taupitz Matthias , Hamm Bernd , Makowski Marcus R.
Published: December 2020

This review summarizes recent developments regarding molecular imaging markers for magnetic resonance imaging (MRI) of prostate cancer (PCa). Currently, the clinical standard includes MR imaging using unspecific gadolinium-based contrast agents. Specific molecular probes for the diagnosis of PCa could improve the molecular characterization of the tumor in a non-invasive examination. Furthermore, molecular probes could enable targeted therapies to suppress tumor growth or reduce the tumor size.
Neuropathic Pain Related to Peripheral Neuropathies According to the IASP Grading System Criteria
Authors: Di Stefano Giulia , Di Lionardo Andrea , Di Pietro Giuseppe , Truini Andrea
Published: December 2020

Neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory system. Neuropathic pain represents a broad category of pain conditions, common complications of peripheral neuropathies, which are characterized by a combination of positive symptoms, including paresthesia and/or dysesthesia and sensory deficits in the painful area. In the present paper, we aimed to assess neuropathic pain frequency and clinical characteristics of peripheral neuropathies due to different aetiologies according to grading system criteria of the International Association for the Study of Pain for a definitive diagnosis of neuropathic pain. Epidemiological studies applying these criteria have been conducted in patients with diabetes, brachial plexus injury, and other traumatic nerve injuries. Neuropathic pain was diagnosed in 37–42% of patients with diabetic peripheral neuropathy, 56% of patients with brachial plexus injury, and 22% of patients with intercostobrachial neuropathy. The most frequent neuropathic pain type was ongoing pain (described as burning or pressing), followed by paroxysmal pain (electric shock-like sensations) and allodynia (pain evoked by brushing and pressure). By providing information on the frequency, clinical signs, and variables associated with neuropathic pain due to different aetiologies, these studies contribute to improving the clinical management of this condition.
Metal-Free Catalysts for the Polymerization of Alkynyl-Based Monomers
Authors: Zhang Jie , Zhang Zhiming , Yang Fulin , Zhang Haoke , Sun Jingzhi , Tang Benzhong
Published: December 2020

Novel polymerizations based on alkyne monomers are becoming a powerful tool to construct polymers with unique structures and advanced functions in the areas of polymer and material sciences, and scientists have been attracted to develop a variety of novel polymerizations in recent decades. Therein, catalytic systems play an indispensable role in the influence of polymerization efficiencies and the performances of the resultant polymers. Concerning the shortcomings of metallic catalysts, much of the recent research focus has been on metal-free polymerization systems. In this paper, metal-free catalysts are classified and the corresponding polymerizations are reviewed, including organobase-catalyzed polymerizations, Lewis-acid-catalyzed polymerizations, as well as catalyst-free polymerizations. Moreover, the challenges and perspectives in this area are also briefly discussed.
Possible Association of Periodontal Disease and Macular Degeneration: A Case-Control Study
Authors: Di Spirito Federica , La Rocca Michele , De Bernardo Maddalena , Rosa Nicola , Sbordone Carolina , Sbordone Ludovico
Published: December 2020

Oral pathogens have been identified in bioptic specimens from Age-Related Macular Degeneration (ARMD) patients, and alveolar bone loss has been related to ARMD. Therefore, the possible association between ARMD and periodontal disease was investigated in the present case-control study, evaluating clinical and radiographic periodontal parameters, primarily, in cases vs. controls and, secondarily, in relation to ARMD risk factors, in cases, to highlight a possible pathogenic link between the disorders. Forty ARMD cases and 40 non-ARMD controls, matched for age (±3 years) and gender and homogeneous for ARMD risk factors, therefore comparable, underwent full-mouth periodontal charting, panoramic radiograph, and medical data, including ARMD risk factors, collection. Statistical analysis was conducted using the language R. Comparisons between groups were made using both traditional t-tests and Yuen’s test with bootstrap calibration. Enrolled subjects were ≥55 years old, and 50 females and 30 males were equally distributed among the two groups. No statistically significant difference was found in clinical and radiographic periodontal parameters in cases vs. controls. In the case group, no differences were found when relating the periodontal parameters to ARMD risk factors, except for Clinical Attachment Level values that were statistically significantly higher in hypertensive ARMD subjects. A possible association between periodontal disease and ARMD may be hypothesized in hypertensive ARMD subjects, with hypertension as a possible pathogenic link between the disorders.
The Impact of COVID-19 Pandemic on Italian Nature-Based Programs in the Educational, Therapeutic, Training and Leisure Areas
Authors: Borelli Chiara , Gigli Alessandra , Melotti Giannino
Published: December 2020

In these times of global crisis caused by COVID-19, there is an urgent need to address the topic of nature-based experiences in education: the pandemic has strongly highlighted both the interdependence between human beings and nature, and the need for mending the dichotomic vision that keeps them separate. Experiential education in natural contexts within an ecological framework might have a strategic role in this crucial period to develop anthropologic, civic, and dialogic conscience (Morin, 2001). Through this study, CEFEO Research Center had the objective of investigating the socio-economic impact of COVID-19 on Italian nature-based programs in the educational, therapeutic, training, and leisure areas. From 28 May to 19 June 2020, an online questionnaire was distributed with the purpose of understanding the socio-economic impact of the pandemic on nature-based programs during the lockdown period and during the period of first reopening, and the related needs and new opportunities for the future. The results highlight a paradox: the COVID-19 crisis has caused more problems for a sector which was already suffering from a lack of funding and of social and institutional acknowledgment. Many agencies working in the field lost months of income and numerous working days, and they are uncertain about the future: they are having difficulties surviving in a moment when we need them more.
Passivhaus
Authors: Moreno-Rangel Alejandro
Published: December 2020

Passivhaus or Passive House buildings are low-energy buildings in which the design is driven by quality and comfort, hence achieving acceptable levels of comfort through post-heating or post-cooling of fresh air. Additionally, Passivhaus building design follows the Passivhaus design criteria, as described in the Passive House Planning Package (PHPP). This article aims to introduce the Passivhaus background, development, and basic design principles. Finally, it also presents a brief description of the performance of Passivhaus buildings.
If the Coronavirus Doesn’t Scare You, the Banners Will—A Case Study of Early COVID-19 Banners
Authors: Dong Hongjie , Zhou Minli , Che Dewei , Bodomo Adams
Published: December 2020

As a crucial element of China’s political and cultural life, “banners”, or biāoyǔ, have been around for decades, in support of national-level policies such as family planning and the governing mottos of Presidents. The banners that have emerged during the Covid-19 pandemic which was also the subject of a national-level driven policy, have been involved in a nation-wide public debate over the language styles of banners used to urge people to stay indoors. Based on the analysis of the early COVID-19 banners and the related online comments, this article analyzes the language style patterns of the banners and the mode of banner circulation. The study found that the manner in which the banners are circulated goes beyond a unidirectional path of on-site instant communication. This process is facilitated by social networks and mass media, which, during circulation, twice created a banner upgrade. The upgrades created decontextualization and function extension of the banners, whereas audience feedback triggered an adaptive adjustment of the language style of the banners. This article suggests that the study of the use and spread of banners, especially the early COVID-19 banners, sheds light on the study of mass communication and discourse style, and also how measures to contain pandemics such as COVID-19 can be communicated.
Prognostic Value of Fibrinogen among COVID-19 Patients Admitted to an Emergency Department: An Italian Cohort Study
Authors: Di Micco Pierpaolo , Russo Vincenzo , Carannante Novella , Imparato Michele , Cardillo Giuseppe , Lodigiani Corrado
Published: December 2020

Introduction: A highly pathogenic human coronavirus able to induce severe acute respiratory syndrome (SARS) has been recently recognized as the cause of the coronavirus disease 2019 (COVID-19); the disease became pandemic after a few months. Little is still known about the laboratory prognostic markers in COVID-19 patients. The aim of our study was to describe the prognostic value of clotting parameters for the prediction of severe form of COVID-19 characterized by acute respiratory distress syndrome (ARDS) at hospital admission. Material and Methods: From a large cohort of 152 patients consecutively admitted from February to March 2020 for fever and dyspnea to the emergency departments (ED) of three Italian hospitals, we evaluated 85 patients with confirmed diagnosis of COVID-19 and 67 patients with acute illness. All patients underwent medical history checks, physical examination, and laboratory evaluation. Prothrombin time (PT), activated thromboplastin time (aPTT), fibrinogen and D-dimer tests were performed and compared, first, between COVID-19 and control groups, and then between COVID-19 patients with or without ARDS. Results: COVID-19 patients were more likely to show abnormal baseline levels of PT, aPTT, D-dimer, and fibrinogen at admission compared to the control group. COVID-19 patients with ARDS showed a statistically significant increase in levels of fibrinogen compared to those without ARDS (720 (621–833) vs. 490 (397.5–601.5); p= 1.8653 × 10−9 (0.0765). A cut-off value of 617 mg/dL had a sensitivity of 76% and a specificity of 79% in identifying COVID-19 patients with ARDS. Conclusion: A serum level of fibrinogen of 617 mg/dL in COVID-19 patients admitted to emergency department may help to identify early those with ARDS.
Design Reliable Bus Structure Distributed Fiber Bragg Grating Sensor Network Using Gated Recurrent Unit Network
Authors: Dehnaw Amare Mulatie , Manie Yibeltal Chanie , Chen Ya Yu , Chiu Po Han , Huang Hung Wei , Chen Guan Wei , Peng Peng Chun
Published: December 2020

The focus of this paper was designing and demonstrating bus structure FBG sensor networks using intensity wavelength division multiplexing (IWDM) techniques and a gated recurrent unit (GRU) algorithm to increase the capability of multiplexing and the ability to detect Bragg wavelengths with greater accuracy. Several Fiber Bragg grating (FBG) sensors are coupled with power ratios of 90:10 and 80:10, respectively in the suggested experimental setup. We used the latest IWDM multiplexing technique for the proposed scheme, as the IWDM system increases the number of sensors and allows us to alleviate the limited operational region drawback of conventional wavelength division multiplexing (WDM). However, IWDM has a crosstalk problem that causes high-sensor signal measurement errors. Thus, we proposed the GRU model to overcome this crosstalk or overlapping problem by converting the spectral detection problem into a regression problem and considered the sequence of spectral features as input. By feeding this sequential spectrum dataset into the GRU model, we trained the GRU system until we achieved optimal efficiency. Consequently, the well-trained GRU model quickly and accurately identifies the Bragg wavelength of each FBG from the overlapping spectra. The Bragg wavelength detection performance of our proposed GRU model is tested or validated using different numbers of FBG sensors, such as 3-FBG, 5-FBG, 7-FBG, and 10-FBG, separately. As a result, the experiment result proves that the well-trained GRU model accurately identifies each FBG Bragg wavelength, and even the number of FBG sensors increase, as well as the spectra of FBGs, which are partially or fully overlapped. Therefore, to boost the detection efficiency, reliability, and to increase the multiplexing capabilities of FBG sensor networks, the proposed sensor system is better than the other previously proposed methods.
Seroprevalence of Mycobacterium avium subsp. paratuberculosis in Dairy Cattle in Khartoum State, Sudan
Authors: Elmagzoub Wisal A. , Adam Nabawia M. , Idris Sanaa M. , Mukhtar Mohamed E. , Abdelaziz Sanaa A. , Okuni Julius B. , Ojok Lonzy , Abd El Wahed Ahmed , Eltayeb ElSagad , Gameel Ahmed A. , Eltom Kamal H.
Published: December 2020

Paratuberculosis, caused by Mycobacterium avium subspecies paratuberculosis (MAP), is a chronic wasting disease mainly of domestic and wild ruminants. It occurs worldwide, causing significant economic losses through decreased productivity, low fertility, increased cull rates and mortality. It is listed by the OIE (World Organization for Animal Health) as a disease of concern to trade in animals. Prevalence of this disease can be studied by detecting anti-MAP antibodies by Enzyme linked immunosorbent Assay (ELISA). The aim of this study was to investigate the current prevalence of MAP infection in cattle in Khartoum State. The overall apparent prevalence of MAP infection was found to be 6.3% and 18.9% at animal and herd levels, respectively. All seropositive animals were cross-bred females of good body condition; most of them (>90%) were >3 years old and >50% were from medium-sized herds in Omdurman. No significant association (p > 0.05) was found between seropositivity and animal herd size. The prevalence of MAP infection in Khartoum State is still low to medium compared to other parts of the world, but it is comparable to those reported from other African countries. Further studies with the view of designing nationwide surveys in domestic ruminants and camels in other states of the country are needed for establishing control programmes.
“Então não verias o divino Agamêmnon com preguiça” (Il. 4. 223): um caso de apóstrofe na Ilíada?
Authors: Canazart Gabriela , Werner Christian
Published: December 2020

Este artigo, partindo de uma argumentação narratológica, discute as alocuções dirigidas ao narratário primário na Ilíada buscando determinar se elas podem ser consideradas apóstrofes, ou seja, se são poeticamente homólogas às apóstrofes a personagens. Seu objetivo secundário é explorar se e como essas alocuções, levando-se em conta seu contexto, sugerem ao narratário outros caminhos para a narrativa se desenvolver.
O azul da ilha, de Évelyne Trouillot
Authors: Ribeiro Ana Cláudia Romano
Published: December 2020

Apresenta-se aqui a tradução coletiva da peça O azul da ilha (Le bleu de l’île), escrita originalmente em francês pela haitiana Évelyne Trouilot em 2005. Em uma breve introdução, o público leitor será apresentado à autora, a seu contexto e ao ponto de partida do trabalho da tradução, realizado no âmbito da disciplina “Iniciação à prática da tradução francês-português” ministrada no curso de Letras da Universidade Federal de São Paulo em 2017. A própria Trouillot, em uma apresentação que também traduzimos, explica o contexto de escrita da peça.
Cícero e o propósito da criação do homem: tradução do capítulo XIV da obra De ira Dei de Lúcio Cecílio Firmiano Lactâncio
Authors: Santos Júnior Cristóvão José dos
Published: December 2020

Esta é a primeira tradução integral para a língua portuguesa do capítulo XIV da obra De ira Dei (Sobre a ira de Deus), atribuída ao escritor africano Lactâncio, que teria vivido entre os séculos III e IV. Essa composição pertence, portanto, à Antiguidade Tardia, um período ainda pouco estudado em pesquisas desenvolvidas em nosso idioma. O escrito apresentado possui um conteúdo apologético, buscando defender a doutrina cristã em oposição ao paganismo. Na décima quarta seção, Lactâncio defende, a partir do pensamento de Cícero, que a natureza humana foi feita para amar ao próximo e honrar a Deus. Por fim, o texto de chegada proposto foi desenvolvido a partir da edição crítica estabelecida pela Sources Chrétiennes (1982).
Revânî’nin İşret-nâme Adlı Eserinde Metin-Minyatür İlişkisi
Authors: BEKEN Burak
Published: December 2020

Divan edebiyatında müstakil edebî türler içinde sâkînâmeler, kaleme alındıkları toplumun sohbet, işret ve zevk anlayışını yansıtmasıyla önemli bir yere sahiptir. Minyatürlü metinler ise genel anlamda okuyucunun tahayyülünü destekler niteliktedir. Sâkînâmelerde minyatürler, Divan şiiri dairesinde konu edilen sâkî, şarap, ‘ıyş u işret gibi kavramların daha net bir şekilde anlaşılmasına katkı sağlayabilir. Revânî’nin İşret-nâme’sinin bir nüshasında da minyatürler metinle birlikte resmedilmiştir. İşret-nâme’de metin-minyatür ilişkisi bu çalışmaya konu edilmiştir. Divan şiirinin ilk müstakil sâkînâmesi sayılan İşret-nâme’nin Staatsbibliothek zu Berlin Ms. or. oct. 3366 numarada kayıtlı nüshasındaki on adet ve aynı kütüphanenin Diez A oct. 144 numarada kayıtlı nüshasındaki bir minyatür incelenerek minyatürlerin nitelikleri belirlenmiştir. Nitelikleri ifade edilen minyatürler ile eserin metin kısmında anlatılanlar arasında fark olup olmadığı, bunların ne ölçüde uyumlu olduğu tespit edilerek minyatürlerin metni tasvir gücü ortaya konmuştur.
Tüberküloz Peritonit Tanısı ile Takip Edilen Olguların Değerlendirilmesi
Authors: KAVAK Şeyhmus , KAYA Şafak , SÖĞÜTÇÜ Nilgün , ALP Vahhac , YILDIRIM Dinçer
Published: December 2020

Amaç: Son yıllarda ekstrapulmoner tüberküloz olgularının arttığı gözlenmektedir. Tüberküloz peritonit nadir görülen ekstrapulmoner tüberküloz formudur. Bu çalışmada tüberküloz peritonit olgularını irdeledik.

Yöntem: Bu çalışma, Ocak 2012-Şubat 2020 tarihleri arasında hastanemizde tüberküloz peritonit tanısıyla takip edilen toplam 23 hastanın verisini içeren retrospektif bir çalışmadır. Veriler hasta dosyalarından, hastane veri kayıt sisteminden elde edilmiştir.

Bulgular: Hastaların 8 (%34.8)’i erkek, 15 (%65.2)’i kadın, yaş ortalaması 41,5±22.1 idi. Beş (%21.7) hastada hipertansiyon, 3 (%13)’ünde diyabetes mellitus mevcuttu. Hastaların 20 (%87)’sinde karın ağrısı, 18 (%78.3)’inde ateş, karında şişlik ve asit, 17 (%73.9)’sinde gece terlemesi, 14 (%60.9)’ünde iştahsızlık mevcuttu. Onaltı (%69.5) hastada radyolojik yöntem olarak bilgisayarlı tomografi ve ultrasonografi, 7 (%30.5) hastada sadece bilgisayarlı tomografi kullanıldı. Hastaların 17 (%73.9)’sinde tanı histopatolojik, 3 (%13)’ünde mikrobiyolojik, 3 (%13)’ünde ise hem mikrobiyolojik hem histopatolojik olarak konuldu.

Sonuç: Tüberküloz peritonitte erken tedavi önemli olduğundan en kısa sürede tanıya gidilmelidir. Radyolojik bulgular nonspesifik olmakla beraber tanıda yardımcıdır. Hem düşündürücü bulgular olması hem de asit sıvısı ve periton incelemesi için ultrasonografi ve bilgisayarlı tomografi oldukça yol göstericidir.
Pregnancy-related Anxiety Scale (The PrAS): Validity and Reliability Study of its Turkish Version
Authors: ŞOLT Ayça , KANZA GÜL Derya
Published: December 2020

Aims: Women may have anxiety during pregnancy. This anxiety may have adverse results both for women and their infants. A scale is needed to determine this anxiety, that occurs during pregnancy, psychometrically. This study aims to conduct the reliability and validity study of the PrAS in Turkish population.

Materia and Method: The study was designed methodologically. The data of the study were collected in the Obstetrics Outpatient clinic of a private hospital located in Istanbul. The participants were composed of 495 pregnant women (primiparous and multiparous).

Results and Discussion: The internal consistency of the Turkish version of the PrAS (Cronbach's alpha = 0.85), the correlation coefficient of the items (0.27 and 0.57) and the confirmatory factor analysis (CFA= 0.35 and 0.98) were found to be high. The PrAS had a high correlation with PRAQ-R2 (multiparous pregnant women r= 0.60, primiparous pregnant women r= 0.65, p= 0.000)

Conclusion: It was demonstrated that the Turkish version of the PrAS was a reliable and valid instrument to assess the anxiety level experienced during pregnancy and this instrument may be easily adapted to other languages.
Marli Wunder: Entre fios, imagens e processo criativo
Authors: Leite Amanda Mauricio Pereira
Published: December 2020

O texto discute o processo de criação da artista plástica brasileira Marli Wunder. Trata-se de um desdobramento da pesquisa de Pós-Doutorado realizada no Departamento de Educação, Conhecimento, Linguagem e Arte da Faculdade de Educação da Universidade Estadual de Campinas (UNICAMP). A partir de um movimento cartográfico, procuramos acompanhar o processo de criação de Wunder a fim de perceber a intensidade da obra e de experimentá-la em suas múltiplas dimensões, nas conexões em redes tecidas com a própria vida. Apoiados em Deleuze (1997), entendemos que a noção de devir-planta funciona como uma linha transversal entre a matéria vegetal e o corpo da artista, uma linha tênue que mistura formas e sensações. Suas fotografias são como escritas de entrelinhas, conjunto de imagens que forçam o pensamento a pensar. Entre fios, fotografias e processo criativo indagamos: o que faz pensar, o que move, o que desestabiliza na obra de Wunder?
Harapan Pada Lansia Dengan Diabetes Melitus Tipe 2
Authors: Ifianti Lailatuz Zalia , Widyastuti Rita Hadi
Published: December 2020

Diabetes melitus adalah gangguan metabolik yang ditandai dengan kenaikan kadar glukosa dalam darah dan dapat menyebabkan  berbagai macam komplikasi sehingga mempengaruhi kualitas hidup lansia. Harapan akan membawa kepada keoptimisan dan meningkatkan kualitas hidup lansia dengan penyakit kronis. Sementara penelitian mengenai dampak harapan masih sangat kurang. Penelitian ini bertujuan untuk mendeskripsikan derajat harapan pada lansia dengan diabetes melitus tipe 2.Penelitian ini menggunakan desain penelitian kuantitatif survei, responden terdiri dari 127 lansia yang menderita DM tipe 2 yang diambil dengan teknik total sampling setelah memenuhi kriteria inklusi. Kuesioner HHI (Herth Hope Index) digunakan untuk mengetahui gambaran harapan. Uji validitas dan reliabilitas telah dilakukan dan hasilnya valid serta reliabel.  Hasil penelitian ini menunjukkan bahwa karakteristik responden adalah didominasi usia 60-74 tahun, sebagian besar berjenis kelamin wanita, tingkat pendidikan didominasi oleh pendidikan SD-SMP, sebagian besar menikah, Suku Jawa, menderita DM < 5 tahun dan tidak mengalami komplikasi. Derajat harapan menunjukkan bahwa responden mempunyai harapan yang tinggi dengan nilai mean sebesar 37.41. Sebagian besar responden merasa hidupnya memiliki nilai dan berharga.Masyarakat dan petugas kesehatan harus membantu lansia mempertahankan derajat harapan yang sudah tinggi dengan menyediakan dukungan sosial dan membantu lansia mencari jalan keluar ketika menghadapi masalah tentang kesehatan dan yang lainnya. Kata Kunci: diabetes mellitus; harapan; lansiaHOPE IN ELDERLY WITH DIABETES MELITUS TYPE 2Diabetes mellitus is a metabolic disorder that signed with the increase of glucose level in blood and can make various complication which influences the elderly’s quality of life. Hope will bring the optimism and increased the  quality of life on elderly with chronic diseases. However, research supporting this effect is lacking. This study was aimed to find out the description of the hope level among elderly with diabetes mellitus type 2. This study was quantitative descriptive with 127 elderly diabetic patients taken by using total sampling technique by fulfilling the inclusion criteria. Herth Hope Index (HHI) questionnaire was used. The validity and reliability was confirmed. The results of this research show that the age of respondent was dominated with 60-74 years old, mostly consist of female. The education level was mostly elementary school, mostly have been married and from Javanese family, suffered from DM for about 5 years and mostly didn’t have complications. For the hope level, the respondent mostly  is in high level with mean score is 37.41. The respondent feel that their life is worth and precious. Based on the results of this research, the society and health center member should help the elderly to maintenance their level of hope by give the support system to the elderly and facilitate the elderly to solve their problem about health or another. Keywords: diabetes mellitus; elderly; hope
Perspectivas de enseñanza en docentes que integran una red de matemáticas: percepciones sobre la integración de TIC y las formas de enseñar
Authors: Hernández Suárez César Augusto
Published: December 2020

El estudio pretendió identificar las perspectivas de enseñanza, las percepciones en la forma de enseñar y las intenciones de integración de las TIC. La investigación se contextualizó dentro del enfoque cuantitativo no experimental transaccional, de carácter descriptivo; así como la técnica cualitativa basada en los grupos de discusión, en un ambiente permisivo, no directivo. La muestra estuvo conformada por 28 docentes que forman parte de la Red de experiencias matemáticas de Norte de Santander-Colombia. Los instrumentos empleados fueron el inventario acerca de las perspectivas de enseñanza (Teaching Perspectives Inventory –TPI-), una pregunta para medir el nivel de uso de las TIC y los registros de la reactividad de los docentes, a través de una discusión grupal en un foro virtual, donde se halló que la perspectiva de enseñanza dominante es la de acompañamiento. Se concluyó que la integración de las TIC está influenciada por las creencias y determina en la práctica la forma de enseñar las matemáticas.
Physico-chemical conditions of crystallization of minerals-phenocrysts in basaltic complexes hosting massive sulfide deposits of the Urals fnd Siberia
Authors: Simonov V.A. , Maslennikov V.V.
Published: December 2020

he paper discusses the physico-chemical formation conditions of minerals-pheno-crysts in basaltic complexes, which host massive sulfde deposits of the Urals and Siberia. It is found as a result of study of melt inclusions that clinopyroxene from basalts of the Valentorka (North Urals) and Kyzyl-Tashtyg (South Siberia) deposits crystallized from melts with similar temperature (1165–1130 and 1210–1085 °С, respectively) and chemical parameters. In both cases, the composi¬tions of basalt-andesite magmas (with features of igneous island arc and back-arc basin systems) evolved with a decrease in FeO, MgO, and CaO contents and increase in K2O and SiO2 contents. Modeling, which is based on the compositions of inclusions and clinopyroxene, showed that miner-als-phenocrysts crystallized from intermediate magma chambers of diferent depth, the parameters of which are consistent with each other and with data on present-day suprasubduction magmatism: Valentorka deposit – 33–27, 23–13, and 10–3 km, 1185–1090 °C; Kyzyl-Tashtyg deposit – 27–20, 15.0–6.7, and 5.0–1.7 km, 1215–1105 °С. Calculations using compositions of melt inclusions show a consistent change of melts from basalts to rhyolites, indicating that the combination of contrasting volcanic complexes of the deposits studied are a result of the evolution of initial basaltic magmas during their uplift to the upper crustal horizons. Our studies of rocks, clinopyroxene and melt inclu¬sions indicate that the basaltic complexes of the Valentorka and Kyzyl-Tashtyg deposits formed in an ancient suprasubduction island arc – back-arc basin system.
ÁNALISE DAS NOTIFICAÇÕES DE VIOLÊNCIA AUTOPROVOCADA POR TENTATIVA DE SUICÍDIO NO ESTADO DA PARAÍBA NO ANO DE 2014 A 2017
Authors: do Nascimento Costa Dáfiny , Andrelly Matos de Lima Maria , Mirelly Ferreira de Lima Lívia
Published: December 2020

OBJETIVO: Analisar as informações contidas nas notificações de violência segundo a lesão autoprovocada com perspectiva na tentativa de suicídio ocorrido no Estado da Paraíba no período de 2014 a 2017. MÉTODO: Trata-se de um estudo quantitativo, descritivo, observacional, cujos dados foram coletados do Departamento de Informático do Sistema Único de Saúde (DATASUS). A partir do Sistema de Informação de Agravos Notificado - SINAN e do Sistema de Informação de Mortalidade - SIM. Analisando os casos notificados comparando com os óbitos ocorridos por lesão autoprovocada. RESULTADOS: Foram registradas 1.572 vítimas de lesão autoprovocada no estado da Paraíba no período de 2014 a 2017, sendo 66% correspondendo ao sexo feminino, a faixa etária que mais cometem esse tipo de violência são os adultos jovens. Em relação aos óbitos com o Código Internacional de Doença (CID) de Lesões autoprovocadas voluntariamente, observou-se um alto número de mortalidade no sexo masculino com 78,8. O maior índice de violência autoprovocada é por envenenamento/intoxicação com 50,8% das ocorrências. CONCLUSÃO: Foi possível avaliar que ainda existem as subnotificações, através da causa morte de lesão autoprovocada voluntariamente, uma vez que as informações registradas no SINAN divergem dos dados encontrados no SIM. Todavia com a educação continuado com os profissionais que preenchem a ficha de notificação pode não só melhorar a coleta dos dados e sua digitação como também o acolhimento do paciente e de sua família.

Palavras chave: Epidemiologia. Tentativa de Suicídio e Lesão Autoprovocada. Violência.
DILEMAS E DESAFIOS DA PARTICIPAÇÃO SOCIAL NOS CONSELHOS DE SAÚDE NO BRASIL
Authors: dos Santos Costa Cilânea
Published: December 2020

OBJETIVO: O presente estudo tem por objetivo fazer uma breve discussão sobre modelo de participação social que se tem desenhado no âmbito da Política de Saúde, através dos Conselhos de Saúde, mecanismos de controle social e ampliação da cidadania, criados a partir da Constituição Federal de 1988. O direito a participação social na saúde é fruto de um intenso debate construído durante o Movimento Sanitário o qual lutava pela democratização da saúde, em contraponto ao modelo privatista em vigência. Tendo em vista, que na atualidade vivenciamos um processo de desconstrução de direitos, em virtude do ideal neoliberal, instalado no País na década de 1990. MÉTODO: optou-se por uma pesquisa de cunho bibliográfico com abordagem qualitativa, cujo método se debruça no dialético, pois este oferece subsídios para a análise do objeto de estudo e seus determinantes. RESULTADOS: Diante disso, ficou evidente que os Conselhos de Saúde não tem se configurado como canal democrático dentro da relação entre Estado e Sociedade civil, ainda vigoram práticas que caminham para rotinização, manipulação política e burocratização em seu funcionamento. CONCLUSÃO: A participação social é indispensável para legitimação das demandas coletivas, torna-se cada vez mais imprescindível que os sujeitos sociais se apropriem desses espaços de participação direta e contribuam na construção do planejamento orçamentário, bem como seu monitoramento, implementação e fiscalização.

Palavras chave: Conselhos de saúde. Direito a saúde. Participação Social. Política de Saúde.
VIOLÊNCIA SEXUAL CONTRA CRIANÇAS E ADOLESCENTES SOB O OLHAR DAS POSSÍVEIS IMPLICAÇÕES NA VIDA DAS VÍTIMAS: UMA REVISÃO DE LITERATURA
Authors: Paula Monteiro do Nascimento Ana , Flávia Henriques Ribeiro Monteiro Ana , Galvão Araújo Lucas , Louis Rodrigues Cavalcanti Mateus , Medeiros Gomes Cavalcanti Paloma , Cavalcanti Rodrigues Raissa
Published: December 2020

OBJETIVO: Este artigo tem como principal objetivo realizar uma discussão a respeito dos impactos da violência sexual em crianças e adolescentes, citar as medidas adotadas pelo governo para reverter essa situação no âmbito da saúde e conhecer o perfil dos agressores tendo como justificativa o crescente número de casos no Brasil. MÉTODO: Utilizou-se a base de dados do PubMed, Scielo, Google acadêmico e documentos fornecidos virtualmente pelo ministério da saúde para estudo e correlação com os dados pesquisados. RESULTADOS: Através dos achados científicos analisados, estima-se que, anualmente, cerca de 225 milhões dos menores são vítimas de abusos sexuais e, destes, a maioria dos casos é do sexo feminino. Os agressores eram homens em mais de 90% dos casos e os resultados apontam que os pais, padrastos e tios foram os principais responsáveis pelo crime de violência sexual. Ainda há muitos municípios, no país, sem cobertura pelo Programa Sentinela. CONCLUSÃO: Não é possível generalizar ou delimitar com precisão os efeitos do abuso sexual, uma vez que a gravidade e a extensão das consequências são individuais e dependem da experiência de cada vítima. Por isso fica evidente que é preciso uma ação conjunta do Governo com o Sistema de Saúde para detecção precoce, a fim de minimizar danos, possibilitar tratamento e acompanhamento adequados, além de identificar agressores.

Palavras chave: Adolescentes. Criança. Violência sexual.
PENGABDIAN KEPADA MASYARAKAT DENGAN KEGIATAN MURAL UNTUK MEMPERCANTIK LAPANGAN ASTAGINA, PADANGSAMBIAN KLOD
Authors: Kusuma Putra Gede Lingga Ananta , Putra I Gede Jaya
Published: December 2020

Beautifying the environment is one form of our concern as creatures who depend on an environment to live. By beautifying an environment will create a comfortable impression and atmosphere to be in that environment. One of the actions that can beautify the environment is to do mural activities on walls or walls that are less attractive in appearance. Mural is an activity of painting or drawing on flat media, walls, walls or large surfaces that are permanent in nature. Based on the results of observations that have been made in the Astagina Field, which is located on Jl. Mt. Tangkuban Perahu No.291, Padangsambian Klod, Kec. Denpasar Bar., Denpasar City, Bali 80117, has one corner of the large wall that is unkempt and unattractive. So that the Bali Design and Business Institute will carry out mural creation activities in Astagina Field to beautify the environment as well as an embodiment of community service programs.