bluuebunny/crossref_metadata_2025 huggingface dataset:
Effectiveness criteria for application of the isolated limb perfusion in soft tissue sarcoma
Authors: Petrochenko N. S. , Burov D. A. , Manikaylo A. E. , Bokhyan B. Yu. , Kharatishvili T. К. , Martynkov D. V. , Kumekhov Z. Yu.
Published: June 2021

It perdormed the literature data analysis on the criteria and methods for assessing the clinical efficacy of the isolated limb perfusion method in the treatment of soft tissue sarcoma. It is noted that the use of isolated limb perfusion is a rather effective method providing local control of the tumor process in locally advanced forms of soft tissue sarcoma. It has been demonstrated that the use of such a neoadjuvant treatment regimen allows administration of the drug with the achievement of high local concentrations of chemotherapeutic drugs with a relatively low incidence of systemic side effects. Criteria for tumor response to therapy, in particular RECIST (Response Evaluation Criteria In Solid Tumors), Choi criteria, adapted for magnetic resonance imaging, are presented. It is noted that a number of studies have studied the possibility of using positron emission tomography with fluorodeoxyglucose labeled with 18F (18F-FDG) to assess the response to treatment in sarcomas. At the same time, it was shown that the results of studying the metabolic response are superior in accuracy to the method of assessment using the RECIST criteria and the assessment performed by the dynamics of the tumor tissue volume has significant potential in assessing the response to isolated limb perfusion in patients with soft tissue sarcoma. The importance of a one-time assessment of positron emission tomography with 18F-FDG parameters and Magnetic Resonance Imaging for soft tissue sarcoma is confirmed by the results of a combined analysis that takes into account both morphological characteristics and quantitative metabolic parameters of the tumor. The high potential of the combined assessment of metabolic and volume-morphological parameters obtained using these methods was demonstrated; it was noted that the combination of positron emission tomography data with 18F-FDG and Magnetic Resonance Imaging enhances the reliability and efficiency of planning and monitoring of soft tissue sarcoma treatment using the isolated limb perfusion method.
THE CENTER OF FOLKLORE AND ETHNOGRAPHY AS A PLATFORM OF PRESERVING, STUDYING AND PROMOTION OF UKRAINIAN FOLKLORE (TO THE 30TH ANNIVERSARY OF THE CENTER)
Authors: Zakalska Yaryna , Shchybria Volodymyr , Baramba Iryna , Overchuk Oksana
Published: June 2021

The article is devoted to the activity of the Center of Folklore and Ethnography of the Institute of Philology of Taras Shevchenko National University of Kyiv on the revival, preservation and popularization of the intangible cultural heritage of Ukrainians at the present stage. The history of development, the basic directions and results of work are characterized.
Temperature anomalies of a cold period on the territory of Ukraine in 2010-2019
Authors:   Odessa State Environmental University, Odessa, Ukraine, Nashmudinova Helena
Published: June 2021

Regional climate change in Ukraine in recent decades is accompanied by an increase in the repetitiveness of intense waves, both heat and cold; there is a tendency to increase the frequency of warm winters, but sometimes there are periods with significant decreases in temperature. The aim of the study is to determine the specifics of the formation of air temperature anomalies in the cold period 2010–2019. According to the distribution of the average monthly air temperature at the stations Odessa, Kiev, Kharkiv, Lviv investigated positive and negative deviations from the climate norm. In January, the average monthly air temperature in most cases was above normal, except for 1–3 years. The maximum positive anomaly was 4–5°C in Kyiv and Lviv (2015), the largest negative deviations were 3.8°C. In February, the trend continues – only 2–3 years with negative anomalies, the largest deviations to 3–6°C in 2011 and 2012, and positive deviations maximum in 2016. In March, negative temperature anomalies were observed 3–4 years, with a maximum of 2–3°C in 2018, positive anomalies in 4–6°C were observed in 2014, 2017. Temperatures in November were variable, with the prevailing positive anomaly, a high of 6–8°C in 2010. The distribution of air temperature in December was characterized by positive deviations of a maximum of 5–6°C in 2011, 2015, 2017 and 2019. Months of the greatest positive and negative air temperature anomalies over Europe have been highlighted. Among the colder months, the biggest anomaly stood out in January 2010 and February 2012 to 5–6°C. Among the warm months, the temperature anomaly was observed in February 2016, positive deviations from the norm to 8°C. Heat waves formed in winter with a zonal type of circulation, when warm moist air from the Atlantic shifted across the periphery of the Icelandic low. In March, waves of heat formed in low–gradient fields. Powerful waves of cold over the European sector were mainly formed under the influence of “eastern processes” in the spread of the Siberian anticyclone to Europe. In some years, significant cooling over Ukraine is formed in cyclonic systems with a high–altitude thermobaric field characterized by polar or ultrapolar hollow.
Man-induced transformation of the territory of Staryi Sambir raion of Lviv Region
Authors:   Ivan Franko National University of Lviv, Lviv, Ukraine, Telish Pavlo
Published: June 2021

Types of man-induced impact in the territory of village councils in Staryi Sambir raion have been analyzed. The most significant changes in the raion’s territory have been caused by agricultural, forestry, pastoral, residential, industrial, and recreational impacts. Many types of impact are characterized by a rather clear landscape confinedness. Each of the types of impact causes different anthropic transformations in specific environmental components. Following P. Shyshchenko’s methodology, the factors of man-induced transformation for the territory of village councils of the raion in question have been estimated on the basis of analysis of the structure of agriculturally used lands. Five levels of territory transformation have been outlined according to the value of the man-induced transformation factor: very slightly transformed, slightly, moderately, severely and very severely transformed. It has been clarified that the territories of village councils with moderate level of transformation stand for almost a half of the raion’s area. A bit smaller is the share of very slightly transformed ones – 24.9% and slightly transformed ones – 23.1% of the territory. The territories of severely and very severely transformed village councils occupy, respectively, 1.6% and 1.5%. These are mainly the territories around the towns of Staryi Sambir, Dobromyl, and Khyriv. The overall man-induced transformation factor for the territory of Staryi Sambir raion is some 3.51.
Research history of geoarcheological sites of the Middle Dnieper Left Bank
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Kravchuk Illia
Published: June 2021

The article presents an analysis of the study of archeological sites by methodology of natural sciences on the left bank of the Middle Dnieper, namely 23 sites from the Middle Palaeolithic to the Iron Ages (11 in Chernihiv region; 2 in Sumy region; 6 in Poltava region; 2 in Kyiv region and 1 in Dnipropetrovsk region). Three stages in the sites research have been established on the basis of the complex of methods applied: 1) 1st half of the 20th century - 1980s – the discovery of majority of the sites and settlements on the left bank of the Middle Dnieper region; mainly geological and palaeontological studies. 2) 1980s–2000 – introduction of new (or improved) natural science methods, the complex interpretation and analysis of former research materials. The first appearance of pollen data in the studied area was an important milestone; 3) the beginning of the 21st century – nowadays – further implementation of pollen and palaeopedological methods in the study of the previously known and newly discovered sites. Uneven distribution of the Palaeolithic sites in the area studied was shown (with their significant concentration in the Desna region). The geoarchaeological sites were studied with a different number of methods – 13 out of 23 sites were dated by the radiocarbon method, 9 sites also had palynological and palaeopedological data, 18 of them had paleontological findings. The most complete and representative information is obtained for the following Palaeolithic sites: Pushkari I, Buhorok, Dobranichivka, Hintsi, Buzhanka II, Obolonnia and the Neolithic site Pohorilivka-Vyrchyshche. The Bronze and Chalcolithic sites in the area were studied less intensely and with less number of methods than the Palaeolithic sites. The necessity for further palynological and palaeopedological studies of the archaeological sites is highlighted.
Features of formation and distribution of zoogenic relief in the Oster River floodplain
Authors:   Nizhyn Mykola Gogol State University, Nizhyn, Ukraine, Filonenko Yurii
Published: June 2021

During 2015–2020, we carried out a series of field studies of zoogenic relief in the Oster River floodplain. In the process, the method of field route observations, polls, photography, morphological and morphometric analyses were actively used. Mathematical methods and computer technologies were used to process and summarize the obtained data. Based on the field research data, it was established that the natural conditions of the Oster River floodplain are favourable for the emergence of zoogenic relief forms. Zoogenic landforms are common here, and their size and location depend on the animal species which live in the area or constantly migrate through it. The influence of individual representatives of the animal world on the formation of the surface of the studied area is presented. It was shown that some of them simultaneously create both accumulative and negative forms of biogenic relief. Accumulative zoogenic landforms are represented in the Oster floodplain by individual small dams and beaver huts; muskrat huts; earthen anthills and anthills formed from dry grass and twigs; molehills; mice’s soil nano-strands; hamster mounds; pico-humps formed by worms and beetles. Among the negative landforms of zoogenic origin there are burrows and burrow nests; underground galleries of animals and insects; nano-basins of forest and field mice; livestock trails and wildlife migration trails; burrowing of wild pigs; footprints of various animals. Beavers, moles, wild boars and ants are found to cover the highest proportion of landform creation activity within the Oster River floodplain. It was also found that the size of most zoogenic landforms in the studied area have the rank of pico- and nano-relief. Relief microforms are much less common. The lifespan of zoogenic landforms can range from tens or even hundreds of years to several hours. It is discovered that fires significantly affect the landforms of zoogenic origin. As a result of the flames, many of the forms change their shape and size, and some even cease to exist.
Development of comparative approach elements in the classical natural geography
Authors:   Institute of Geography of NAS of Ukraine, Kyiv, Ukraine, Davydiuk Mykola
Published: June 2021

At the current stage of scientific research development, the comparative approach, an efficient logical method of cognition of the Earth’s nature, does not lose its significance in the light of new and classic scientific methods, particularly in geography. The article presents the in-depth analysis of the origins and development of comparative approach in natural geography on the basis of national geographical sources. The researchers who applied comparative approach to their studies are also presented. The time intervals – stages of development of comparative approach in geography are defined. Two of them are considered – pre-antique and antique. Such periodization is based on time, because this approach has been developed and improved along with the development of physical-geographical ideas and knowledge. The stages of its development were defined on the basis of different, characteristic for them, logical features of comparative approach. Considering the various aspects, one can learn about various significant events during the various stages of developing of geographical sciences. The pre-antique stage of origin and the enriched development of the components of the comparative approach (stage 1) were characterized by all significant comparisons, and therefore comparisons, the content of which, in particular, even reached the idea of possible distant lands similar to the known ones. The beginnings of geospatial representations in our ancestors began to take shape at the dawn of human culture. On the background of the limited cognitive tools of ancient science, the comparative approach was distinguished by its capabilities and applications as one of the most effective in the then scientific and practical knowledge of the world.
On methodology of palaeogeographical studies of karst cave deposits of Ukraine
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Avdieienko Yuliia
Published: June 2021

New approaches developed within the complex palaeogeographic methodology of cave deposits studies for reconstruction of the past ecological conditions are presented in the paper. The relevance and reliability of results of such studies are shown on the cases from the previous research of cave systems in Ukraine. The methodology based of palynological and lithological (including grain-size analysis) study of terrigenous cave deposits is proposed, and the advantages of their complex application within the multidisciplinary palaeoenvironmental study are proved. The reliability of palaeovegetational reconstructions based on pollen studies of clastic cave deposits is confirmed by the compatibility of their results with those obtained from coeval subaerial deposits. The same patterns were shown by a comparison of pollen from hyaena coprolites in the cave and their enclosing sediments. It has been found that the content of redeposited pollen in the clastic sediments of caves depends on their particle size distribution, sharply increasing in sandy deposits. The grain-size composition of cave deposits also provides information on the genesis of deposits and, thus, indirectly, on paleoenvironmental conditions. Changes in clay, large silt and sand fractions are of main importance for the interpretation of the results. A direct correlation of paleoclimatic signals obtained by the results of pollen and lithological analyses with the indicators of magnetic susceptibility has been established. The use of these paleogeographic methods for studying cave deposits, namely pollen analyses, lithological (in particular, grain-size), palaeontological, petromagnetic, palaeogenetic, radiocarbon and paleomagnetic methods, will be able to control the reliability of the reconstruction by collate them. Multidisciplinary study of the cave deposits has a great potential for reconstructions of the ancient Man environments as deposits of many caves include archaeological horizons of different material cultures from the Early Palaeolithic to the Early Iron Age.
Depolimerisasi Kitosan Menggunakan Sinar Ultraviolet dan Katalis Asam Klorida
Authors: Faustine Devi , Setyaningsih Iriani , Hardiningtyas Safrina Dyah
Published: June 2021

Kitosan merupakan produk alam hasil deasetilasi kitin yang memiliki rantai molekul yang panjang dan berat molekul yang tinggi, hal ini menjadikan kitosan terkendala dalam proses pengaplikasiannya. Untuk mengatasi hal tersebut perlu dilakukan proses depolimerisasi yang dapat menurunkan berat molekul kitosan dan memendekkan rantai molekul kitosan. Penelitian ini bertujuan menentukan pengaruh lama penyinaran sinar ultraviolet terbaik yang akan menghasilkan kitosan dengan bobot molekul rendah yang dapat larut dalam air atau pelarut netral. Depolimerisasi kitosan dalam penelitian ini dilakukan dengan memanfaatkan radiasi sinar ultraviolet dan asam kuat untuk memotong rantai polimer kitosan hingga menghasilkan kitosan dengan rantai yang lebih pendek dan dapat larut dalam air atau pelarut netral. Depolimerisasi dimulai dengan melarutkan kitosan dan HCl 2%, selanjutnya disinari dengan sinar ultraviolet selama 45 menit, 60 menit, 75 menit. Larutan kitosan dipresipitasi menggunakan isopropil alkohol, dan difiltrasi dengan kain nylon ukuran 40 mesh. Kitosan yang telah memiliki pH 7 dikeringkan untuk mendapatkan kitosan larut air. Kitosan larut air yang didapat dianalisis dengan membandingkan tiap perlakuan yang diberikan dan kitosan bahan baku. Penggunaan sinar ultraviolet dan larutan HCl berpengaruh terhadap karakteristik depolimerisasi kitosan yang dihasilkan. Perlakuan terpilih berada pada kitosan yang didepolimerisasi perlakuan lama penyinaran sinar ultraviolet 75 menit dengan hasil rendemen 70,07±14,00%, kelarutan 99,80±0,17%, derajat putih 99,99±0,00%, viskositas 49,78±0,31 cP, bobot molekul 169,46±0,30 kDa, dan zeta potensial 73,03±1,92 mV. Penurunan bobot molekul dan viskositas pada karakteristik kitosan larut air dalam perlakuan tersebut menunjukkan bahwa proses depolimerisasi kitosan telah terjadi dimana efek depolimerisasi meningkat seiring dengan meningkatnya lama penyinaran sinar ultraviolet.
Penambahan Genjer (Limnocharis flava) pada Pembuatan Garam Rumput Laut Hijau untuk Penderita Hipertensi
Authors: Nurjanah Nurjanah - , Mardiono Jacoeb Agoes , Ramlan  , Abdullah Asadatun
Published: June 2021

Rumput laut hijau jenis Ulva lactuca dapat dimanfaatkan sebagai bahan baku pembuatan garam rumput laut. Garam rumput laut rendah natrium dan tinggi kalium menjadi alternatif mengurangi penyakit hipertensi. Penelitian ini bertujuan untuk menentukan jumlah/rasio penambahan genjer (Limnocharis flava) dalam menghasilkan garam rumput laut yang sesuai standar garam diet untuk penderita hipertensi. Parameter yang dianalisis adalah komposisi mineral, kadar natrium klorida (NaCl), aktivitas dan kapasitas antioksidan serta cemaran logam berat. Pembuatan garam rumput laut dilakukan dengan cara mencampurkan bahan baku dengan akuades perbandingan 1:10, dan dipanaskan pada suhu 40 ºC selama 10 menit, filtrasi pada suhu 60 ºC selama 30 jam. Ekstrak U. lactuca mengandung IC50 48,64 ppm (DPPH) dan kapasitas antioksidan 246,92 µmol/g (CUPRAC). Garam U. lactuca menghasilkan rendemen 32,36%, rasio Na:K 1,49; NaCl 23,90%, aktivitas antioksidan 93,24 ppm (DPPH), dan kapasitas antioksidan 129,15 µmol/g (CUPRAC). Setelah ditambahkan genjer (1:1) dihasilkan rendemen 22,78%, rasio Na:K 0,59; NaCl 21,05%, aktivitas antioksidan 118,87 ppm (DPPH), dan kapasitas antioksidan 104,07 µmol/g (CUPRAC). Penambahan genjer sebesar 50% dapat menurunkan rasio Na:K menjadi 0,59 demikian juga dengan kadar NaCl, dengan aktivitas dan kapasitas antioksidan mengalami penurunan relatif kecil.
Coaxial Electrohydrodynamic Bioprinting of Pre-vascularized Cell-laden Constructs for Tissue Engineering
Authors: Mao Mao , Liang Hongtao , He Jiankang , Kasimu Ayiguli , Zhang Yanning , Wang Ling , Li Xiao , Li Dichen
Published: June 2021

Recapitulating the vascular networks that maintain the delivery of nutrition, oxygen, and byproducts for the living cells within the three-dimensional (3D) tissue constructs is a challenging issue in the tissue-engineering area. Here, a novel coaxial electrohydrodynamic (EHD) bioprinting strategy is presented to fabricate thick pre-vascularized cell-laden constructs. The alginate and collagen/calcium chloride solution were utilized as the outer-layer and inner-layer bioink, respectively, in the coaxial printing nozzle to produce the core-sheath hydrogel filaments. The effect of process parameters (the feeding rate of alginate and collagen and the moving speed of the printing stage) on the size of core and sheath lines within the printed filaments was investigated. The core-sheath filaments were printed in the predefined pattern to fabricate lattice hydrogel with perfusable lumen structures. Endothelialized lumen structures were fabricated by culturing the core-sheath filaments with endothelial cells laden in the core collagen hydrogel. Multilayer core-sheath filaments were successfully printed into 3D porous hydrogel constructs with a thickness of more than 3 mm. Finally, 3D pre-vascularized cardiac constructs were successfully generated, indicating the efficacy of our strategy to engineer living tissues with complex vascular structures.
Validation of the Hungarian PHQ-15. A latent variable approach
Authors: Stauder Adrienne , Witthöft Michael , Köteles Ferenc
Published: June 2021

Somatic symptoms without a clear-cut organic or biomedical background, also called “medically unexplained” or “somatoform” symptoms, are frequent in primary and secondary health care. They are often accompanied by depression and/or anxiety, and cause functional impairment. The Patient Health Question­naire Somatic Symptom Scale (PHQ-15) was developed to measure somatic symptom distress based on the frequency and bothersomeness of non-specific somatic symptoms. The study aimed to (1) evaluate the Hungarian version of the PHQ-15 from a psychometric point of view; (2) replicate the bifactor structure and associations with negative affect described in the literature; and (3) provide the Hungarian clinical and scientific community with reference (normal) values split by sex and age groups. PHQ-15, depression (BDI-R), and subjective well-being (WHO-5) scores obtained from a large (n = 5020) and close to representative community sample (Hun­garostudy 2006) were subjected to correlation analysis and linear structural equation modeling. The PHQ-15 showed good internal consistency (Cronbach’s α = 0.810; McDonald’s ω = 0.819) and moderate to strong correlation with the BDI-R (rs = .49, p < 0.001) and WHO-5 (rs = -.48, p < 0.001). Fit of the bifactor structure was excellent; in independent analyses, the general factor was strongly associated with depression (β = 0.656±0.017, p < 0.001) and well-being (β = -0.575±0.015, p < 0.001), whereas the symptom specific factors were only weakly or not related to these constructs. The PHQ-15 score was higher in females and showed a weak positive association with age. The Hungarian PHQ-15 is a psychometrically sound scale which is positively associated with depression and ne­gatively related to subjective well-being. The bifactor structure indicates the existence and meaningfulness of a gene­ral factor representing the affective-motivational component of somatic symptom distress. The Hungarian version of the PHQ-15 is a brief and usable tool for the pre-screening of somatization disorder (DSM-IV) or somatic symptom disorder (DSM-5). The reported reference values can be used in the future for both clinical and research purposes.
A new method to determine the optimal orientation of Slim Modiolar cochlear implant electrode array insertion
Authors: Horváth Bence , Perényi Ádám , Molnár Fiona Anna , Csanády Miklós , Kiss József Géza , Rovó László
Published: June 2021

Our goal was to determine the optimal orientation of insertion of the Slim Modiolar electrode and develop an easy-to-use method to aid implantation surgery. In some instances, the electrode arrays cannot be inserted in their full length. This can lead to buckling, interscalar dislocation or tip fold-over. In our opinion, one of the possible reasons of tip fold-over is unfavourable orientation of the electrode array. Our goal was to determine the optimal orientation of the Slim Modiolar electrode array relative to clear surgical landmarks and present our method in one specified case. For the measurement, we used the preoperative CT scan of one of our cochlear implant patients. These images were processed by an open source and free image visualization software: 3D Slicer. In the first step we marked the tip of the incus short process and then created the cochlear view. On this view we drew two straight lines: the first line represented the insertion guide of the cochlear implant and the second line was the orientation marker (winglet). We determined the angle enclosed by winglet and the line between the tip of the incus short process and the cross-section of previously created two lines. For the calculation we used a self-made python code. The result of our algorithm for the angle was 46.6055°. To validate this result, we segmented, from the CT scan, the auditory ossicles and the membranaceous labyrinth. From this segmentation we generated a 3D reconstruction. On the 3D view, we can see the position of the previous lines relative to the anatomical structures. After this we rotated the 3D model together with the lines so that the insertion guide forms a dot. In this view, the angle was measured with ImageJ and the result was 46.599°. We found that our method is easy, fast, and time-efficient. The surgery can be planned individually for each patient, based on their routine preoperative CT scan of the temporal bone, and the implantation procedure can be made safer. In the future we plan to use this method for all cochlear implantation surgeries, where the Slim Modiolar electrode is used.
Comparison of direct costs of percutaneous full-endoscopic interlaminar lumbar discectomy and microdiscectomy: Results from Turkey
Authors: Ünsal Ünlü Ülkün , Şentürk Salim
Published: June 2021

Microdiscectomy (MD) is a stan­dard technique for the surgical treatment of lumbar disc herniation (LDH). Uniportal percutaneous full-endoscopic in­terlaminar lumbar discectomy (PELD) is another surgical op­tion that has become popular owing to reports of shorter hos­pitalization and earlier functional recovery. There are very few articles analyzing the total costs of these two techniques. The purpose of this study was to compare total hospital costs among microdiscectomy (MD) and uniportal percutaneous full-endoscopic interlaminar lumbar discectomy (PELD). Forty patients aged between 22-70 years who underwent PELD or MD with different anesthesia techniques were divided into four groups: (i) PELD-local anesthesia (PELD-Local) (n=10), (ii) PELD-general anesthesia (PELD-General) (n=10), (iii) MD-spinal anesthesia (MD-Spinal) (n=10), (iv) MD-general anesthesia (MD-General) (n=10). Health care costs were defined as the sum of direct costs. Data were then analyzed based on anesthetic modality to produce a direct cost evaluation. Direct costs were compared statistically between MD and PELD groups. The sum of total costs was $1,249.50 in the PELD-Local group, $1,741.50 in the PELD-General group, $2,015.60 in the MD-Spinal group, and $2,348.70 in the MD-General group. The sum of total costs was higher in the MD-Spinal and MD-General groups than in the PELD-Local and PELD-General groups. The costs of surgical operation, surgical equipment, anesthesia (anesthetist’s costs), hospital stay, anesthetic drugs and materials, laboratory wor­kup, nur­sing care, and two main groups (PELD-MD) me­dication diffe­red significantly among the two main groups (PELD-MD) (p<0.01). This study demonstrated that PELD is less costly than MD.
Krónikus dialízis kapcsán kialakult destruktív cervicalis spondylarthropathia esete
Authors: Berta Balázs , Komáromy Hedvig , Schwarcz Attila , Kajtár Béla , Büki András , Kuncz Ádám
Published: June 2021

A case of a 61-year-old male patient suffered chronic renal failure and dialysed for 23 years with destructive cervical spondylarthropathy is presented. The patient presented with sudden onset of cervical pain radiating into his shoulders without neurological deficits. CT and MRI of the cervical and thoracic spine revealed severe destructive changes and compressive fractures of C6 and C7 vertebrae which caused the narrowing of the nerve root canals at these levels. A 360-degree fixation was performed to treat the unstable fracture and the patient’s pain (C6 and C7 corpectomy, autolog bone graft replacement of the two vertebral bodies, anterior plate fixation and posterior instrumentation with screws and rods). Postoperatively the patient had no significant pain, no neurological deficit and he was able to manage independent life himself. During the immediate follow-up CT of the neck showed the satisfactory position of the bone graft and the metal implantations. The 6 months follow-up CT revealed the anterior migration of the two screws from the Th1 vertebral body and 2 mm ventral elevation of the caudal end of the plate from the anterior surface of the Th1 vertebral body. The 1-year follow-up could not be performed because the patient died due to cardio-pulmonary insufficiency. This is the second Hungarian report of a chronic dialysis related severe spondylarthropathy which may cause pathologic fractures of the vertebral bodies. The typical radiological and histological findings are discussed. This disease affect patients’ quality of life and the conservative treatment alone seems to be ineffective in most cases. Based on the literature and personal experiences, the authors suggest 360-degree fixation of the spine to provide sufficient stability for the vertebrae of ”bad bone quality”, and early mobilisation of the patient can be achieved.
COVID 19: The catalyst for digital transformation in the hospitality industry?
Authors:   NOVA Information Management School (NOVA IMS), Universidade Nova de Lisboa, Lisbon, Portugal, António Nuno ,   CITUR- Universidade do Algarve, Faro, Portugal, Rita Paulo ,   NOVA Information Management School (NOVA IMS), Universidade Nova de Lisboa, Lisbon, Portugal
Published: June 2021

Despite its benefits related to efficiency, creating better customer experiences, increasing revenue, and supporting decision-making, until the outbreak of COVID-19 digital transformation was not on many hotels’ strategic plans. However, like in many other industries, the COVID-19 physical distancing good practices and governments’ restrictions acted as catalysts and promoted hotel digitalization. To this end, a questionnaire was administered to 51 hotel managers to verify if that happened in Portuguese hotels and what processes were most impacted. Results showed that 92% of the hotel managers agreed that COVID-19 promoted the digitalization of processes, with most organizations considering that online meetings and technology productivity tools are here to stay. Hotels’ digitalization has the potential to generate high-efficiency gains both in public-facing operations and back-office operations. This study highlights these implications and intends to spur researchers to investigate the practical impact of these implications on business efficiency and social theory.
РОЗВИТОК БАНКІВСЬКОЇ СИСТЕМИ РЕСПУБЛІКИ УЗБЕКИСТАН В УМОВАХ ЕКОНОМІЧНИХ РЕФОРМ
Authors: Зайналов Жахонгир , Хотамкулова Мадіна
Published: June 2021

У статті аналізується ситуація в банківському секторі Узбекистану, показано наявність ряду системних проблем, що перешкоджають його розвитку відповідно до економічними перетвореннями і потребами суспільства. Науково обгрунтовано необхідність реформування банківської системи країни, визначені основні напрями її реалізації щодо підвищення ефективності та забезпечення фінансової стабільності банківської системи, зниження державної частки в банківському секторі, підвищення доступності та якості фінансових послуг.
“Compliance” empresarial: la labor de empresa más allá de los bienes jurídico-penales. Perspectiva española
Authors: Ballesteros Sánchez Julio
Published: June 2021

Este artículo analiza, desde una óptica de derecho comparado, el vínculo que une el estudio del fenómeno del criminal compliance, capaz de evitar o reducir hasta niveles de tolerancia social los riesgos emanados de la actividad empresarial, con las prioridades estratégicas globales (seguridad humana, desarrollo sostenible) establecidas por organismos internacionales como, por ejemplo, Naciones Unidas. Se considera que este enfoque servirá para que los Estados democráticos fortalezcan el Estado de derecho y, particu­larmente, las pautas legales relativas a la prevención en materia de compliance dentro y fuera de las fronteras nacionales. Así, el presente trabajo, para cuya redacción se examinó una variedad de documentos estratégicos penales y extrapenales, advierte que el modelo preventivo ofrecido por el compliance en aras de proteger bienes jurídico-penales puede ser útil para contener otros riesgos que causan inseguridad en las sociedades actuales.
Mortality Outcomes of Single-staged versus Multi-staged Complete Coronary Revascularization in Multivessel Non-ST Elevation Myocardial Infarction Patients
Authors: ALICI Gökhan , QUİSİ Alaa , GENC Omer , HARBALIOĞLU Hazar , ALLAHVERDİYEV Samir , YILDIRIM Abdullah , URGUN Örsan Deniz , GÜR Mustafa
Published: June 2021

Aim: The aim of this study was to compare the short-term and long-term mortality results of single-stage percutaneous coronary intervention (SS-PCI) and multi-stage percutaneous coronary intervention (MS-PCI) strategies in patients diagnosed with non-ST segment elevation myocardial infarction (NSTEMI) with multivessel disease.
Material and Methods: A total of 298 consecutive patients diagnosed with multivessel NSTEMI (71 (23.8%) patients in the SS-PCI group and 227 (76.2%) patients in the MS-PCI group) were included in this study. Data regarding mortality were obtained from the health information system of our institute and national health registry.
Results: Although in-hospital mortality rates were found to be significantly higher in univariate analysis in the SS-PCI group compared to the MS-PCI group (14.1% (n=10) vs 4.0% (n=9); p=0.005), it was not independently associated with total mortality in multiple model. Among the parameters predicted mortality determinants, low hemoglobin (odds ratio (OR)=0.485, 95% confidence interval (CI)=0.332-0.708; p=0.002), No-reflow occurrence (OR=6.194, 95% CI=1.310-29.300, p=0.021), not using post dilatation (OR=0.287, 95% CI=0.085-0.970, p=0.045) were independently associated with total mortality.
Conclusion: There was no statistical difference in overall mortality between the two study groups in multivessel NSTEMI patients who underwent complete coronary revascularization with the SS-PCI and MS-PCI strategy, while low hemoglobin, No-reflow phenomenon, and not using post-dilatation were found as independent predictors of mortality.
Reševanje problemov mehanike tal
Authors: Jelušič Primož
Published: June 2021

Namen učbenika je aplicirati zakonitosti mehanike tal na praktičnih primerih. Prikazani so osnovni postopki za ovrednotenje fizikalnih in mehanskih lastnosti zemljin, ki so osnova za učinkovito reševanje problemov v geotehniki. Glede na obstoječo literaturo s področja mehanike tal je vsebina učbenika razdeljena na 16 poglavij: Uvod, Klasifikacija zemljin, Tri-fazni sestav zemljine, Napetosti v zemljini, Napetosti v sloju tal, Darcyjev zakon, Prepustnost zemljin, Precejanje podzemne vode, Napetosti in deformacije, Eno-dimenzionalni tlak, Konsolidacija, Lezenje, Strižna trdnost, Določitev parametrov strižne trdnosti, Napetosti-teorija elastičnosti in Stabilnostna analiza.
La Alianza del Pacífico y el CPTPP: ¿alternativas para la solución de diferencias ante la OMC?
Authors: Gallardo-Salazar Natalia , Tijmes-IHL Jaime
Published: June 2021

El sistema de solución de diferencias de la Organización Mundial del Comercio (OMC) está en crisis desde que su Órgano de Apelación dejó de funcionar en diciembre de 2019. Como consecuencia, el Órgano de Solución de Diferencias de la OMC no puede adoptar el informe de un grupo especial si una parte en la diferencia notifica su intención de apelar. En ese contexto, el presente artículo analiza qué factores pueden influir en la decisión de las partes reclamantes de recurrir a dos acuerdos comerciales regionales (ACR), la Alianza del Pacífico y el Tratado Integral y Progresista de Asociación Transpacífico (CPTPP), como foros alternativos a la solución de diferencias de la OMC. Tras un análisis comparativo de las normas de solución de diferencias en ambos ACR, y en el Entendimiento sobre Solución de Diferencias de la OMC, concluimos que los factores procesales e institucionales serán posiblemente relevantes para las partes reclamantes que deseen seleccionar un foro de solución de diferencias.
Woordeboek Afrikaans-/Xam - /Xam-Afrikaans
Authors: Raper Peter
Published: June 2021

/Xam is die taal wat gepraat is deur die /Xam-Boesmans wat binne menseheugenis suid van die Oranjerivier gewoon het, in die gebied wat vroeër bekend was as die Kaapkolonie. Mettertyd het Hollands en later Afrikaans hulle taal van voorkeur geword, en die /Xam-taal het in onbruik geraak. Hierdie amper vergete taal is hoofsaaklik deur WHI en DF Bleek opgeteken, en dit vorm ŉ belangrike deel van die kulturele erfenis van tallose nasate van die /Xam en ander San wat vandag Afrikaanssprekend is. Hierdie woordeboek is onontbeerlik vir almal wat deel is van hierdie erfenis, veral in hierdie tyd van hernieude belangstelling in die Eerste Mense en hulle eie identiteit, kultuur en taal. Die /Xam-taal het ŉ invloed gehad op al die ander tale in die land, wat veral gesien kan word in plekname en name van diere. Hierdie woordeboek sal nuttig wees vir studente, navorsers en belangstellendes, asook vir pleknaamowerhede wat die brontale van name moet bepaal.
Effects of COVID-19 on Health Care Workers
Authors: Whalen Mary , Smith Penny C.
Published: June 2021

COVID-19 continues to spread across the United States with a continued increase in reported infections and deaths. How this virus effects pregnancy, particularly mothers and their infants around and after delivery, is of particular concern for health care workers. Moreover, concerns for compassion fatigue in the health care worker, as they attempt to provide comprehensive care to this population, is a documented concern that could have long-term effects on workers' ability to provide care. This article will describe the current concerns for the transmission of COVID-19 from the mother to the infant and how that has affected recommendations from several national and international organizations around maternal/infant testing, isolation, breastfeeding, and the infant requiring neonatal intensive care. Effects that changing recommendations may have on health care workers and care delivery, and how these may contribute to compassion fatigue, will also be discussed.
COVID-19 and the NICU: #Zeroseparation
Authors: Discenza Deborah
Published: June 2021

COVID-19's first wave created chaos for new NICU families as they struggled to cope with the challenge of a fragile infant along with a pandemic. Safety was paramount due to a lack of understanding around how the virus transmits, but much has been learned since then. The next wave of the virus needs to have a rethink around family separation. World leader organization European Foundation for the Care of Newborn Infants (EFCNI) provides insight into the challenges with the first wave and suggests ideas around rethinking how families interact with their baby in the subsequent waves.
SARS CoV-2 (COVID-19) Current Pharmacotherapy for Mother and Infant
Authors: Thigpen Jim
Published: June 2021

The novel coronavirus disease 2019 (COVID-19), appeared in the United States over 1 year ago. This virus has a wide range of presentations, from being asymptomatic to causing severe acute respiratory syndrome, which can lead to death. It has led to a worldwide effort to find effective treatments, from repurposed medications to new discoveries, as well as the push to develop effective vaccines. As the race to fight this pandemic unfolds, this column provides what is currently available to combat this virus, how it has been utilized in the pregnant population, and what data have been made available about how these treatments affect fetal development and the neonate.
Bazı Toprak Özellikleri İle İlişkili Olarak Arazi Kullanımı ve Arazi Örtüsünün Toprak Organik Karbon Stokuna Etkisi
Authors: YILMAZ Merve , DENGİZ Orhan
Published: June 2021

Toprak organik karbon (TOK) stokunun mekânsal dağılımını etkileyen temel faktörlerin belirlenmesi, TOK stok tahminlerinin doğruluğunu artırmak için kritik öneme sahiptir. Bu çalışmanın temel amacı, Türkiye’nin Orta Karadeniz Bölgesi’nde yer alan Samsun ilinin Vezirköprü ilçesinin 111 km2’lik kısmını kaplayan alanda arazi kullanımı-arazi örtüsü ile bazı toprak özelliklerinin TOK stoku üzerindeki etkilerini belirlemektir. Çalışma alanının arazi kullanımını ve arazi örtüsünü belirlemek için Triplesat uydu görüntüsü kullanılmıştır. Orman, mera, yerleşim ve tarım arazileri olmak üzere dört ana arazi kullanımı ve arazi örtüsü belirlenmiştir. Elde edilen sonuçlara göre, çalışma alanında bazı toprak özelliklerinin ve arazi kullanımının-arazi örtüsünün TOK yoğunluğunun mekânsal değişimini istatistiksel olarak önemli düzeyde etkilediği saptanmıştır. Çalışma alanında TOK stok miktarı yüzey (0-20 cm) topraklarında 4.79 ton ha-1 ile 94.10 ton ha-1 arasında, yüzey altı (20-40 cm) topraklarda ise 5.16 ton ha-1 ile 8.86 ton ha-1 arasında değişmektedir. Farklı arazi kullanımları arasında en yüksek TOK stoku miktarının yüzey toprağında 53.356 ton ha-1 ile ormanlık alanlarda iken, en düşük TOK stoku miktarının ise 34.048 ton ha-1 ile tarım arazilerinde olduğu belirlenmiştir.
Analisis Penerapan Media Pembelajaran Geogebra dalam Mengembangkan Kemampuan Komunikasi Matematis Siswa Pokok Bahasan Sistem Persamaan Linier Dua Variabel
Authors: Arnanda Alvias Noviantika , Dafik Dafik , Oktavianingtyas Ervin , Harmi Harmi , Firmani Indyah
Published: June 2021

Abstract: The objective of this research was to find out students’ learning activity on Linear Equation System of Two Variables subject using Geogebra learning media, to find out if there was an increase in the students’ mathematic communication skills on Linear Equation System of Two Variables subject using Geogebra learning media, and to describe the students’ mathematic communication skills on Linear Equation System of Two Variables subject using Geogebra learning media. This research was conducted at SMP Negeri 1 Ngusikan. Based on the data in the school, the students’ mathematic communication skills was still low, so the use of Geogebra media was expected to increase students’ mathematic communication skills. This research applying qualitative research. The data were collected by tests and interview. To analyzing the students’ mathematic communication skills, the researcher did pre-test and post- test. The result showed that the application of Geogebra learning media can increase the students’ mathematic communication skills on Linear Equation System of Two Variables subject. It proved from the students work process in accordance with the indicators of students’ mathematic communication. Furthermore, the students’ mathematic communication skills will be described by the factors which include the learning process, students’ attitudes and comprehension, also giving question that can measure mathematical communication skills continuously.

Keywords: Mathematic communication skills, Geogebra, Linier Equation System of Two Variable
Profil Kemampuan Komunikasi Geometris Siswa Kelas 8 di Era Pandemi Covid 19 Ditinjau dari Tipe Kepribadian Florence Littauer
Authors: Hariyanto Nanang Hadi , Sunardi Sunardi , Yudianto Erfan , Nariyati Nariyati
Published: June 2021

The geometric communication ability profile is a description of communication skills that can help someone express and understand geometric concepts through an image. The purpose of study was to describe the geometric communication skills profile of 8th graders during the covid 19 pandemic in terms of the personality type of florence littauer. this type of research is a descriptive study with a qualitative approach. The results of this study indicate that the first sanguinis student has good communication skills, the second sanguinis student has quite good communication skills. The first choleric type students have good communication skills, while the second choleric students have poor communication skills. The first melancholic type student has poor communication skills, while the second melancholic student has fairly good communication skills. The firs phlegmatic tipe student has very good communication skills, while the second student has quite poor communication skills.

Keyword: Communication, Geometry, Personality
Eksplorasi Etnomatematika pada Bangunan Candi Jabung di Desa Jabung Probolinggo sebagai Bahan Ajar Siswa
Authors: Fadillah Mohamad Yasin , Sunardi Sunardi , Setiawan Toto' Bara , Astari Nida'an Chofiyyah
Published: June 2021

Ethnomatematics is mathematics that is practiced by cultural groups, such as rural and urban communities in carrying out certain cultural activities. Culture can be in the form of works such as buildings that have certain characteristics. Mathematics with the application of culture will make it easier for students in the learning process. This study aims to determine the ethnomatematics of Jabung temple in Jabung village, Probolinggo and as a material for making student test packages in the form of questions. This type of research is qualitative research with an ethnographic approach. Data collection methods used were observation and interviews. This study shows that there are mathematical concepts in the Jabung temple including rectangle, triangle, circle, rhombus, tube, beam, similarity, congruence, translation, reflection, dilatation. The results of this study were student test packages for class IX SMP / MTs. which contains ethnomatematics in Jabung temple.

Keywords: ethnomatematics, jabung temple, test packages
Translation and Psychometric Testing of the Indonesian Version of the Preparedness for Caregiving Scale
Authors: Sari Ike Wuri Winahyu , Nirmalasari Novita
Published: June 2021

Background: Although many previous studies have used the Preparedness for Caregiving Scale (PCS), it has not been translated and validated in Indonesia. Purpose: This study aimed to translate and evaluate the PCS’s psychometric adequacy among family caregiver of non-communicable disease (NCD) patients in Indonesia. Methods: The linguistic of the PCS was validated using a standard forward-backward process. The Indonesian version was approved with Content Validity Index (CVI). Then a cross-sectional survey was conducted to establish the construct validity of the PCS to measure caregiver preparedness. A purposive sampling approach was used to recruit 40 consenting family caregivers of NCD patients. The PCS sum score was correlated with each item using Pearson product-moment. The internal consistency of the Indonesian version of the PCS (I-PCS) was assessed using Cronbach’s alpha. Results: The Item-CVI (I-CVI) and Scale-level CVI (S-CVI) of the I-PCS were 1.00. It showed the high content validity of the I-PCS. The I-PCS  revealed a Cronbach’s alpha of 0.933 for the total score. The Pearson-r was more than 0.320 indicated that the item valid. Conclusion: The I-PCS is appeared to be valid and reliable for measuring the caregiver preparedness of NCD patients in Indonesia.