bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Lingkungan Kerja, Pengetahuan Regulasi dan Kompetensi Terhadap Kinerja
Authors: Salatin Yeti Nurul , Tabrani
Published: April 2024

Tujuan penelitian adalah mengetahui pengaruh ling­kungan kerja terhadap motivasi kerja, mengetahui pengaruh pengetahuan regulasi terhadap motivasi kerja, mengetahui pengaruh kompetensi pegawai terhadap motivasi kerja, mengetahui pengaruh lingkungan kerja terhadap kinerja pegawai, mengetahui pengaruh pengetahuan regulasi ter­hadap kinerja pegawai, mengetahui pengaruh kompetensi pegawai terhadap kinerja pegawai, mengetahui pengaruh motivasi kerja terhadap kinerja pegawai. Populasi dalam penelitian ini adalah seluruh tenaga kesehatan di Puskesmas Bangun Galih Tegal yaitu sebanyak 48 pegawai. Teknik pengambilan sampel menggunakan sampel jenuh atau studi sensus. Dengan demikian maka jumlah sampel juga sebanyak 48 pegawai. Hasil penelitian adalah tidak terdapat pengaruh lingkungan kerja motivasi kerja, tidak terdapat pengaruh pengetahuan regulasi terhadap motivasi kerja, terdapat pe­ngaruh positif dan signifikan kompetensi terhadap motivasi kerja, tidak terdapat pengaruh lingkungan kerja terhadap kinerja tenaga kesehatan, terdapat pengaruh positif dan sig­nifikan pengetahuan regulasi terhadap kinerja tenaga kese­hatan, terdapat pengaruh positif dan signifikan kompetensi terhadap kinerja tenaga kesehatan, tidak terdapat pengaruh motivasi kerja terhadap kinerja tenaga kesehatan
Pengaruh Store Atmosphere, Kualitas Pelayanan, dan Harga Produk Terhadap Loyalitas Pelanggan Melalui Kepuasan Pelanggan
Authors: Dewi Tri Filia , Mubarok Abdulloh
Published: April 2024

Penelitian ini dilakukan untuk mengetahui pengaruh dari store atmosphere, kualitas pelayanan, dan harga produk pada loyalitas pelanggan Café Eatboss. Analisis yang digunakan yaitu PLS. hasil yang didapatkan yaitu store atmosphere tidak berpengaruh pada loyalitas, kualitas pelayanan berpengaruh pada loyalitas, harga produk berpengaruh pada loyalitas, store atmosphere ber¬pe¬ngaruh terhadap kepuasan, kualitas pelayanan tidak ber¬pe¬ngaruh terhadap kepuasan, harga produk berpengaruh pada kepuasan, kepuasan pelanggan berpengaruh pada loyalitas pe¬la¬nggan cafe Eatboss Tegal, kepuasan pelanggan mampu memediasi pengaruh store atmosphere terhadap loyalitas pelanggan, kepuasan pelanggan tidak mampu memediasi pengaruh kualitas pelayanan terhadap loyalitas pelanggan, kepuasan pelanggan mampu memediasi pengaruh harga produk terhadap loyalitas pelanggan.
THE Comparative Analysis of Technological Content Knowledge (TCK) through The Digital Module and Google Classroom in Integrated Science Learning
Authors: Hayati Muriani , Arfiani Yuni , Fatkhurrohman M. Aji
Published: April 2024

The development of information technology has become one of the measures in ranking the nation's competitiveness. The success of technology integration in education comes primarily from curriculum content, learning processes, and the use of technology in education. A complex planning is needed in order to produce the output as expected, so in this case, the domain of capability in technological knowledge content (TCK) known as Technological Content Knowledge is needed, especially in science material. This study aims to analyze the comparison of learning outcome and TCK skills by user experience through used technology which is digital web modules and Google classroom. The subjects of this study were 6th semester students to obtain learning outcome. This study was a quasi-experimental study. This study used two e-learning platforms, namely digital modules and Google Classroom, to compare learning outcomes and questionnaire to analyse their TCK abilities. The study showed that there were differences using a digital module and using Google classroom by t- test. The use of digital modules further enhances cognitive learning outcomes than with Google classroom. The profile of TCK using the digital module is better than using GC.
Media Pembelajaran Video Animasi Stop Motion pada Materi Sistem Sirkulasi Manusia untuk Meningkatkan Keterampilan Berpikir Kritis Siswa
Authors: Muzammil Imal , Kurniasih Surti , Jaenudin Dadang
Published: April 2024

study aims to produce products in the form of Stop motion animation learning media and obtain information on students' critical thinking skills on circulation system materials. This research is a development research or Research and Development (R&D) with a research design carried out referring to the 4-D development model by Thiagarajan et al., (1974). The 4-D development model consists of define, design, develop, and dessiminate stages. Of the four steps, only three steps were carried out in accordance with the limitations of the study. Data collection is carried out in a quantitative descriptive manner. The results of this study showed that the learning media got an average score of 3.66 which means it is very good based on expert assessment, the CVR score got a score of 3.90 and CVI got a score of 0.94. The results of  the student's critical thinking skills test before using stop motion animation  media scored  56.53 and after using the media scored 82.53.
Analisis Hasil Belajar Biologi Siswa Kelas XII MIPA Pada Materi Pertumbuhan dan Perkembangan Berdasarkan Ranah Kognitif Taksonomi Bloom Revisi
Authors: Mila Nor , Jumrodah  , Fadillah Az Zahro
Published: April 2024

This study aims to determine the analysis of biology learning outcomes for class XII MIPA students on growth and development material based on the cognitive domain of the revised bloom taxonomy using a descriptive method with a quantitative approach. Descriptive research aims to explain and describe the facts obtained in accordance with a certain point of view. The technique of determining the research subject was carried out by purposive sampling in which the research subjects were students of class XII MIPA MAS Muslimat NU. The results of the analysis of biology students found that the classification of evaluation questions for Biology class XII MIPA on growth and development material based on the cognitive domain of the Revised Bloom's Taxonomy already contains questions with an understanding indicator (C2) of 48% and an indicator of applying (C3) of 52%. The learning outcomes of class XII MIPA students based on the cognitive domain of the Revised Bloom's Taxonomy are that students are more able to solve questions with an understanding indicator (C2) of 80% compared to questions with an apply indicator (C3) of 63%.Keywords: revised bloom taxonomy, cognitive, analysis
Pengaruh Penggunaan Mobile Learning Berbasis Website Terhadap Kemampuan Literasi Sains Materi Sistem Tata Surya
Authors: Anindita Rahma , Hayati Muriani Nur , Widiyanto Bayu
Published: April 2024

Penelitian ini bertujuan untuk mengetahui peningkatan kemampuan literasi sains peserta didik pada materi sistem tata surya, dan untuk mengetahui perbedaan kemampuan literasi sains peserta didik yang menggunakan media mobile learning berbasis website dan tanpa menggunakan media mobile learning berbasis website. Populasi dalam penelitian ini peserta didik kelas VII di salah satu SMP Kota Tegal dengan teknik pengambilan sampel yaitu cluster random sampling yang berjumlah 31 peserta didik di kelas eksperimen dengan menggunakan media mobile learning berbasis website dan 30 peserta didik di kelas kontrol tanpa menggunakan media mobile learning berbasis website. Penelitian ini memperoleh nilai signifikansi uji paired sample t-test sebesar 0,000 < 0,005 artinya terdapat perbedaan yang signifikan antara media pembelajaran mobile learning berbasis website dengan kemampuan literasi sains dan untuk uji n-gain diperoleh mean persentase kelas ekperimen dan kelas kontrol sebesar 71,49% dan 65,24% artinya pada kelas eksperimen berpengaruh menggunakan media mobile learning berbasis website dibandingkan kelas kontrol tanpa menggunakan media mobile learning berbasis website.
Perbandingan Respon Siswa Terhadap Praktikum IPA di Sekolah Dasar Indonesia dan Thailand
Authors: Widiyanto Bayu , Aryanti Khusnul Khatimah Ismi
Published: April 2024

Kegiatan praktikum merupakan suatu kegiatan yang perlu dilakukan karena dalam mempelajari materi IPA selain mempelajari teori, peserta didik juga  perlu untuk mempelajari secara langsung materi yang dipelajari untuk memperoleh pengetahuan dan pengalaman secara nyata. Kegiatan praktikum di setiap sekolah tentunya berbeda dan tergantung pada ketersediaan sarana dan prasarana sekolah, hingga sumber daya yang ada. Tujuan dari penelitian ini adalah untuk membandingkan Respon Siswa terhadap praktikum IPA di salah satu Sekolah Dasar di Indonesia dengan Thailand. Metode penelitian ini yaitu menggunakan metode kualitatif-komparatif. Data diambil melalui kegiatan wawancara dan     observasi. Subyek penelitian ini adalah 5 Siswa di salah satu sekolah dasar yang terletak di Satun, Thailand Selatan serta 5 siswa di salah satu sekolah dasar yang terletak di Indonesia. tepatnya di kecamatan Larangan, kabupaten Brebes, provinsi Jawa Tengah. Berdasarkan penelitian yang telah dilakukan, dapat diketahui bahwa respon siswa di sekolah dasar Thailand maupun di sekolah dasar Indonesia, memberikan respon yang sama ketika dilakukan praktikum IPA yaitu merasa senang, dan merasa lebih mudah dalam memahami materi. Kegiatan praktikum IPA di kedua sekolah dasar tersebut sama-sama terdapat pemanfaatan lingkungan sekitar khususnya praktikum yang berkaitan dengan tumbuhan. Namun sarana dan prasarana yang tersedia di kedua sekolah tersebut memiliki perbedaan.
Implementasi Model Pembelajaran Discovery Learning Guna Meningkatkan Motivasi Belajar IPA Peserta Didik Kelas VII SMP
Authors: Prayogi Dwi Prayogi
Published: April 2024

Tujuan penelitian ini untuk mengetahui stratei implementasi model Discovery Learnig (DL), meningkatkan motivasi belajar IPA peserta didik kelas VII D SMP Negeri 3 Banguntapan Bantul. Jenis penelitian ini adalah penelitian tindakan kelas dengan tahap lesson study (plan do and see). Penelitian ini dilakukan sebanyak dua siklus dengan materi yang diajarkan yaitu sistem tata surya, bumi dan satelitnya, fase-fase bulan. Instrumen yang digunakan berupa angket motivasi belajar (awal dan akhir), lembar observasi kegiatan peserta didik dan observasi keterlaksanaan pembelajaran guru. Proses pembelajaran dilakukan sesuai dengan sintaks yang terdapat dalam model DL. Hasil penelitian menunjukkan keterlaksanaan model DL sudah baik dengan terlaksananya semua langkah pada siklus 2. Hasil tes posttest menunjukkan peningkatan rerata nilai dari siklus 1 sebesar 67.33 ke siklus 2 sebesar 83.33. Hasil nilai angket menunjukkan nialai N-gain sebesar 0,77% dengan kriteria tinggi. Dengan demikian, dapat disipulkan bahwa penerapan model DL dapat meningkatkan motivasi belajar IPA peserta didik kelas VII D.
Comparison Emission and Fuel Consumption of Engine of 6000 Watts Electric Generator Fuelled with Biogas and Gasoline
Authors: Artha Negara Gede , Gde Tirta Nindhia Tjokorda , Bandem Adnyana Wayan , Ngurah Putu Tenaya Gusti , Astawa Ketut , Sari Nindhia Tjokorda , Kumar Shukla Shaildendra , Jhalani Amit
Published: April 2024

The electric generator with a capacity 6000 watts was prepared in this research to be able to be fuelled with flexible fuel. The engine in this generator was 4 strokes engine, single cylinder of 4 stroke spark ignition engine with cylinder volume of 420 cc that can be operated fully with biogas and if biogas is not available, the engine can also be run by using gasoline with an easy switch mechanism. The method developed in this research was different from the idea of dual-fuel which was the fuel was mixed. Two types of Biogas are prepared in this research, type 1 biogas was purified from H2S and H2O, and type 2 of biogas was purified from CO2, H2S, and H2O. The gasoline type that was used in this work was the pertalite with a research octane number (RON) was 90. The engine was run with no load (idle position) and with a load 250 watts and the effect on emission and fuel consumption were recorded and analyzed. The result indicates that the average fuel consumption of using biogas type 1 is about 44.24 L/Minute in idle position and increases to become 45.35 L/minute with load 250 watts. For biogas type 2 the fuel consumption is found about lower, that is 43.76 L/Minute in idling position and increase to reach 45.04 L/minute for with load 250 watts.It is noted here that by using gasoline the fuel consumption is 0,023 L/ Minutes in idle position and a little bit increase to become 0.024 L/minute for 250-watt load. The CO emission is found at 3.91 % vol. for gasoline engine in idle position and reduce a little bit to become 3.5 % vol. with load 250 watts. The emission is found excellent if biogas is used as a fuel comparing gasoline. For biogas type 1, the CO emission is found 0.06 % vol. in idle position and just a bit increase to become 0.07 % vol. if loaded at 250 watts. The best performance is found for biogas type 2 that the CO emission is found 0.04% vol. and still in this value at loading 250 watts.
Application for New Student Admission at SMKS Al-Akhyar II Jakarta with C4.5 Algorithm
Authors: Eka Meilan Dwi , Tri Sutrisno , Bagus Mulyawan
Published: April 2024

Al-Akhyar II Jakarta Vocational High School (Smk) is a school that has been accredited with A superior. However, the application of new student admissions still has some difficulties in knowing the potential of prospective students who will attend school. This makes schools have to selectmore students who will be accepted at Smks Al-Akhyar IIJakarta.Therefore,a method is needed to identify prospective new students at school. Data Mining with the C4.5 Algorithm can be used to select and classify prospective new students at school by making a decision tree based on existing data and selecting prospective students. Data on prospective students whoregisterandtaketests in the 2019 academic year, 2020 and 2021 will be selected using theC4.5method whichwill latersee students who are accepted at Smks Al-Akhyar IIJakarta. The resultsthat have been tested using training data and comparing thetraining dataandtestingdatahaveanaccuracyof97%using theC4.5method.Testswere also carried out on 89 respondents who agreed that this design was carried out to overcome problems at Smks Al-Akhyar II Jakarta.
HEALTHY FOOD MENU RECOMMENDATION SYSTEM AT INDONESIAN GORRY GOURMET COMPANY USING ELECTRE METHOD (ELIMINATION ET CHOIX TRAUDISANT LA REALITE)
Authors: Damartantyo Anggito , Pragantha Jeanny , Jaya Perdana Novario
Published: April 2024

One way to maintain a healthy lifestyle is to consume balanced food intake with proper nutrition and diet. Gorry Gourmet is a company that produce healthy food, which elements to enhance health. This company is overseen by qualified nutritionists to ensure their healthy meal’s. The meal is considered healthy if it provides the body with enough nutritions. There are a number of issues that make it challenging for people to choose "suitable meal" according to user's needs. Since everybody dietary requirements are unique and cannot be generalized, a system that can offer the recommendations of healthy meal will be developed. The result is a website that give recommendation menu meal that meets the user's needs. The system employed Elimination Et Choix Traduisant La Realite (ELECTRE) approach to determine which healthy meal available from the Gorry Gourmet.
Application of Solar Photovoltaic Technology for Energy Saving and Sustainable Co-Living Buildings
Authors: Hizkia Nathanael , Trisno Rudy
Published: April 2024

Abstract. One of the efforts to protect the environment is to follow the Kyoto Protocol, Paris Agreement, and conferences related to global warming. The tangible manifestation of this issue is that buildings have begun to pay attention to the concept of sustainable architecture by changing single-use energy to renewable energy. The purpose of this paper is to find out how much energy can be saved by co-living buildings that apply passive design and solar photovoltaic systems using the EDGE application. The research method used is a quantitative method by paying attention to the calculation of EDGE energy and the total of solar photovoltaic. This paper concludes that the co-living buildings can be categorized as an energy-efficient building with the use of photovoltaic and with a passive design system. Then the building can be classified as an advanced energy-efficient building with an energy saving of 47% and a break-even point of 216 days. The novelty of this paper is that the use of EDGE application that can determine the amount of energy savings that is very significant in communal residential buildings in Indonesia.
Analysis Of Thermal Comfort In L 609 Classroom By Using SST k-ꞷ Turbulence Model
Authors: Gozali Ryo , Darmawan Steven , Tanujaya Harto
Published: April 2024

In today's era, more and more people spend most of their time indoors, with artificial climatic conditions, where thermal comfort is a basic factor such as a glazing system (ventilation), both for dimensions and material characteristics, this basic factor is very important because it affects the parameters involved in thermal comfort. One of the requirements for thermal comfort is good air circulation, good air circulation can also prevent the spread of the COVID-19 virus that is currently engulfing the world.Therefore, research is needed to analyze the air flow engineering in the room, especially the classroom to get results that will later be seen whether it has met the demands of room comfort, especially thermal comfort. The purpose of this study is to provide recommendations for the configuration of air circulation in the L609 classroom and perform a CFD analysis on air circulation in the classroom which can create thermal comfort. Based on all the simulation results carried out with 2 outlet configurations and 5 different speed fan configurations, the obtained results are in accordance with the ASHRAE 55 standard in 2020 only in the first configuration with a speed of 0.79 m/s. in the second configuration all the simulation results obtained are not in accordance with the thermal comfort limit according to ASHRAE 55 in 2020 because the speed obtained is more than 0.8 m/s and the temperature obtained is more than 297 K. Considering the COVID-19 pandemic, there must be circulation air in order to break down the aerosol concentration of the COVID-19 virus itself. Therefore, the author recommends using a classroom configuration with an open door so that air circulation can flow properly.
Development of the Gadingsari Village Tourism Geographic Information System Application
Authors: Then Raymond , Trisnawarman Dedi , Hugeng
Published: April 2024

Gadingsari Village is a city located in Jogjakarta, has cultural diversity as an asset of regional wealth, and must be developed as optimally as possible. Many tourists visit tourist attractions in Gadingsari Village, but there are difficulties in choosing the tourist attractions visited due to limited information about tourist attractions in Gadingsari Village. The other problems are congestion problems, cost problems, time problems,s, and labor problems. The purpose of this study is to create a geographic information system for tourism in Gadingsari village. The system is built using PHP and MySQL programming languages as database management as well as the application of the Dijkstra algorithm used to find the shortest path based on the smallest weight from one point of departure to another. The tests carried out in this study used the User Acceptance Test, aiming to determine the user's understanding of the application created. The resulting geographic information system consists of several features, namely the information feature of tourist places, and the feature of finding the fastest route to the tourist spot. In the fastest route search feature, the Dijkstra algorithm works optimally so that it can quickly find the fastest route to tourist places in Gadingsari Village.
The Effects of the Covid-19 Pandemic on Big Data Artificial Intelligence
Authors: Johan Suwinto
Published: April 2024

The Covid-19 pandemic has changed people's behavior. Artificial Intelligence is made based on big data of people's behavior. Financial institutions use AI in making credit decisions. The AI basis of credit decisions is made based on existing customer Big Data. This customer's Big Data has changed as a result of the Covid-19 pandemic. Changes in Big Data mean that the AI of financial institutions in decision making must be adapted to the new behavior. This study aims to discuss the changing community behavior variables related to the granting of credit approvals. This study uses a qualitative method with a literature review. This study concludes that length of stay, home ownership, occupation, length of work, expense ratio, age, bank account, awareness of fintech, usage of fintech and demographic variables have changed. These variables need to be adjusted as a result of changes in the behavior of the Covid-19 pandemic.
The Rank of Factors Affecting Labor Productivity on Construction Projects
Authors: Faustine Celine , Waty Mega
Published: April 2024

Human resources or labor is one of the factors that influence the success of a construction project. Based on this

statement, it is necessary to analyze labor productivity. Many factors can affect labor productivity. This

research aims to determine the ranking of factors that affect labor productivity in high-rise building

construction projects in Jabodetabek. These factors are divided into 2 parts, namely internal factors, and

external factors. Internal factors are factors derived from within labor control and external factors are factors

derived from outside labor control. The method used in this research is a quantitative research method using a

questionnaire. Furthermore, this research is analyzed using IBM SPSS software for validity and reliability

testing and analyzed using the Relative Importance Index (RII) to determine the ranking of these factors.

Based on the results of the validity and reliability tests, 18 variables were declared valid and reliable. The

highest ranking of the factors that affect labor productivity when viewed as a whole is work skills which is a

variable from internal factors with an RII value of 0,906, while the highest ranking of external factors is

equipment quality with an RII value of 0,883.
Comparison of Building Information Modeling and Conventional Methods for Concrete and Rebar Quantity Take-Off
Authors: Tresnandhini Kusumaningroem Tika , Gondokusumo Onnyxiforus
Published: April 2024

Calculation of Quantity Take-Off (QTO) of concrete and rebar must be carried out accurately and consistently. Design modeling also often changes so that technology is needed to simplify and speed up work. The application of Building Information Modeling (BIM) is one way to reduce errors and speed up QTO calculations. One of the BIM software that can be used to carry out QTO work for concrete and rebar is Revit, which is produced by the Autodesk company. The use of Revit is still often encountered obstacles, but these obstacles can be anticipated by conducting an analysis. The analysis carried out include comparative analysis of calculation results, analysis of initial design time requirements and analysis time requirements if there is a design change, and analysis of advantages and obstacles in using Revit. The data was obtained by conducting interviews and calculating the QTO of concrete and rebar using Revit and conventional methods. The results show that the use of Revit is recommended. This is because Revit can speed up the calculation time for the QTO of concrete up to 49% and the QTO of rebar up to 20% for the initial design stage, the calculation of QTO of concrete if there is a design change up to 90%, and QTO of rebar up to 67% when compared to the conventional method. Respondents also stated that they prefer using the Revit method compared to conventional methods. This study shows that there are no difference results for the QTO of concrete and there is a slight difference for the QTO of rebar up to 0.6742%.
STEGANOGRAPHY IMPLEMENTATION OF INSERTION OF CONFIDENTIAL DATA ON DIGITAL IMAGE MEDIA
Authors: Dharma Kusumah Kelvin , Pragantha Jeanny , Jaya Perdana Novario
Published: April 2024

Sending confidential messages through the internet is very vulnerable to theft, many irresponsible parties try to get information from these messages for personal gain. So that the secret message can only be read and understood by certain parties, a way is needed to hide the message, namely with steganography. Steganography is a technique to hide messages in media such as text, images, audio and video so that the media that is inserted looks like normal. Bit-Plane Complexity Segmentation (BPCS) is a steganographic method used in message embedding. This method has a large message insertion capacity. The insertion is done by replacing the complex bit-pane with a secret message block. In this final project, a software is developed that applies the steganography method with the BPCS method on uncompressed images. In addition, tests were conducted to analyze the suitability of the BPCS method on uncompressed images. The final result obtained is a software capable of handling message insertion. The conclusion of this research is that the BPCS algorithm is proven to be able to solve the problem of inserting messages into image media.
COMPARATIVE ANALYSIS OF WIND PRESSURE OF UNTAR MAIN BUILDING
Authors: Vincent  , Leman Sunarjo
Published: April 2024

Wind flows from high to low pressure due to presence of solar heat. The movement of wind in air is freely

exposed to obstacles such as buildings, especially in large cities. Buildings that are exposed to wind create

pressure for building which can be compressive or suction. In this study, wind pressure analysis was used in

three ways, that is with MIDAS GEN software, Autodesk CFD, and with manual calculation analysis

referring to Indonesia National Standard (SNI) 1727:2020. The building modeling used as test is main

building of UNTAR campus 1 with total height 89 m. The tested wind direction moved from south to north

and from west to east at a wind speed 32 m/s. The results of analysis showed that percentage of wind

pressure results between MIDAS GEN with manuals was at least 5.66% for both wind directions and

between CFD and manuals at least 0.7% for wind directions from south to north. The results from CFD also

show that result the main building surface wind pressure for wind flows moving from south to north results in

wind load in the edge area building smaller than in the central area building. The amount of wind pressure in

center of surface can be 4 to 5 times greater than wind pressure at the edge of surface.
2D Web-Based Battle Game "MONSTER BEATer" With Rhythm-Base Combat System
Authors: Sundriansyah Kevin , Pragantha Jeanny , Andana Haris Darius
Published: April 2024

“Monster BEATer” is a rhythm genre game with 2D graphics developed for the Web. This game is developed by

Unity game engine with the C# programming language. In this game, player will control the musical note

character Bita to fight against musical notes which turned into monsters. The game has 10 levels with

different songs and obstacles. This game offers the freedom to play using either a PC/Laptop or smart phone as

long as it is connected to the internet. The Monster BEAter game testing is done by blackbox testing, alpha testing

and beta testing methods. The test results show that the Monster BEATer game is a game that can be played

anywhere as long as it has internet connection, has a high level of difficulty and has a unique gameplay.
Modified K-Nearest Neighbor Web Based Chatbot as Service and Academic Information School
Authors: Natanael  , Christanti Mawardi Viny
Published: April 2024

At a time when everything is done on an Online basis starting from office activities, teaching and learning activities especially administrative activities school. Where in the activity, aninformant needs to be can serve academic and non-academic information needs for para parents of students and other parties. Chatbot is one of the means to overcome these needs by presentingfeatures that allows for someone to ask when and where. Therefore, in the conclusion that chatbot can be a public means especially on schools - schools that can implement their uses as one school information sources other than the school's business. This Chatbot made using the Modified K-Nearest Neighbor method or can be briefed MKNN. MKNN is the latest version of the previous method, K-Nearest Neighbor where in the application MKNN method does the process additional after Euclidean Distance calculation, Weight Voting. Premise from the weight voting method itself is the biggestweight calculation, so chatbot will calculate the value of the shortest distance to the database from the chatbot then after completion, the chatbot will calculate the value weight or information from that distance so that the results that can be from this are the shortestdistance to the data class that is being addressed by carrying the weight of information biggest or most. This is used to facilitate the deep chatbot determine the category of a database so that it can provide answers that more certain and accurate.
The development of pharmaceutical biotechnology in Kharkiv: to the 125th anniversary of “Biolik” enterprise
Authors: Krasnopolsky Yu. M.
Published: April 2024

Aim. To study the development of pharmaceutical biotechnology in Ukraine on the example of the history of the Kharkiv enterprise “Biolik” over the past 125 years.
Materials and methods. Analytical and comparative research methods, as well as bibliosemantic review were used in the article.
Results and discussion. The development of the scientific and technological school of the enterprise “Biolik” in the production of drugs based on biotechnology, such as vaccines, serums, probiotics, artificial nanoparticles, etc., was studied covering the period from the end of the XIX-th century and to the present time.
Conclusions. It has been shown that the enterprise “Biolik” has a significant potential (production areas, equipment, technological documentation, staff, etc.). The enterprise can produce immune-biotechnological and original medicines. We can hope that this potential of the enterprise will allow it to successfully resume the production of high-tech drugs in Ukraine.
The study of some pharmacognostic aspects of Ferula persica Wild. (Apiaceae) roots in the flora of Azerbaijan
Authors: Kerimli E. H. , Kerimov Yu. B. , Isaev J. I. , Zulfugarova P. V. , Akhmedov E. Yu. , Maslov O. Yu.
Published: April 2024

Aim. To determine the component composition of the monoterpene fraction of F. persica roots and identify the localization of biologically active substances in the raw material.
Materials and methods. The identification and quantitative analysis were performed using gas chromatography – mass spectrometry. The raw material was collected during the full seed ripening in the vicinity of the village Dzhangi in the Gobustan region of Azerbaijan.
Results and discussion. Using gas chromatography – mass spectrometry, 15 compounds of monoterpenes were identified. The predominant components were heneicosane – 5.10 %; tetradecane – 3.29 %; disulfide, bis(1-methylpropyl) – 2.86 %; heptadecane – 2.50 %; 9,12,15-octadecatrienoic acid 2,3-bis(acetyloxy)propyl ester – 2.39 %; thiophene, 2,3,4-trimethyl- – 2.05 % in the dry raw material. In addition, it was found that resin was localized in large schizogenous receptacles.
Conclusions. The content of monoterpenes in F. persica roots has been determined using gas chromatography – mass spectrometry. The roots contain monoterpenes of heneicosane; tetradecane; disulfide, bis(1-methylpropyl); heptadecane; 9,12,15-octadecatrienoic acid 2,3-bis(acetyloxy)propyl ester. Thiophene and 2,3,4-trimethyl predominate in the raw material.
Development of conditions for isolation of antidepressant paroxetine from biological fluids
Authors: Karpushyna S. A. , Baiurka S. V. , Halkevych I. Y. , Ihlitska S. I. , Altukhov O. O. , Bylov I. E.
Published: April 2024

Aim. To develop optimized conditions for isolating the new antidepressant paroxetine from model blood and urine samples by the liquid extraction followed by the determination of the analyte using the UV spectrophotometric method.
Materials and methods. The studies were performed with model samples of the donor blood and urine spiked with paroxetine. In the sample preparation of blood, the form elements were previously precipitated by 10 % solution of trichloroacetic acid. Endogenous impurities were removed by the extraction purification with chloroform from an acidic medium at pH 1, and paroxetine was extracted from the biological fluids under study with ethyl acetate at pH 10. The organic extracts obtained were further purified using the TLC method. After that, the determination of paroxetine in the eluates obtained from chromatograms was performed using the UV spectrophotometric method.
Results and discussion. The Rf value of paroxetine in the mobile phase of ethyl acetate-methanol-25 % ammonium hydroxide solution (85:15:10) was 0.42 ± 0.02. The UV spectra of eluates from chromatograms had absorption maxima at wavelengths of 265 ± 2, 272 ± 2 and 293 ± 2 nm and matched with the UV spectrum of a standard solution of paroxetine in 0.1 M solution of hydrochloric acid. The quantitative determination was performed at λmax293 nm according to the equation of the calibration curve y=0.0094x–0.02. The methods developed allowed to isolate 70.0 ± 4.0 % of paroxetine from the urine, 26.0 ± 3.0 % from the blood plasma and additionally 5.4 ± 0.6 % of the antidepressant studied from the blood cell sediment after its preliminary separation from the blood plasma.
Conclusions. The optimized conditions for sample preparation of model blood and urine samples by the liquid extraction method in relation to paroxetine have been determined. The results obtained are of applied practical significance for creating an algorithm in the toxicological study of biological fluids for the presence of this antidepressant in fatal drug intoxications.
Development of the composіtіon and technology of the herbal mixture with the cerebroprotectіve actіon
Authors: Marchenko M. V. , Bohutska O. Ye. , Marchenko Ya. S
Published: April 2024

Aіm. To determine the prospects for using the plant raw material for the creation of herbal medicines with the cerebroprotective effect, as well as to develop the composition and technology of a new medicine of natural origin.
Materіals and methods. The study objects were black horehound (Ballota nigra L.) herb, white dead nettle (Lamium album L.) herb, and Austrian wormwood (Artemisia austriaca) herb. Experimental studies were conducted using modern physical, physicochemical, pharmacotechnological, and mathematical methods of analysis.
Results and dіscussіon. Based on the analysis of scientific sources on the situation with cerebrovascular diseases (CVD) and the range of drugs for their treatment, it has been proven that to improve the quality of therapy, it is rational to conduct a complex pharmacotherapy with the use of herbal medicines. We have proposed a new drug with the cerebroprotective action based on the plant raw material. The medicinal product was obtained in the form of the herbal mixture, which included black horehound herb, white dead nettle herb, and Austrian wormwood herb. The rational technology of the drug has been theoretically and experimentally substantiated. A block diagram of the herbal mixture has been developed, and the critical parameters of its production have been determined. The pharmacotechnological studies of the plant raw material and the drug obtained have been conducted.
Conclusіons. Based on the results of the work conducted, the data scientific sources on the spread of CVD have been analyzed and summarized; the expediency of using the plant raw material in medicines for a complex pharmacotherapy of CVD has been proven; the composition and technology of the drug from black horehound herb, white dead nettle herb, and Austrian wormwood herb in the form of the herbal mixture with the cerebroprotective action for internal use have been developed.
The study of antidepressant properties of new 1,2,3-triazolo-1,4-benzodiazepine derivatives
Authors: Botsula I. V. , Kireyev I. V. , Mazur M. O. , Chebanov V. A.
Published: April 2024

Anxiety-depressive disorders are among the most common mental health conditions and often cause significant functional impairment, affecting a person’s quality of life. Research conducted in recent years indicate the importance of studying and searching for new substances based on benzodiazepines, in particular triazolobenzodiazepines, for the treatment of anxiety states and disorders, as well as determining the presence of other biological activities of these compounds.
Aim. To study the antidepressant activity of new derivatives of 1,2,3-triazolo-1,4-benzodiazepines in the Porsolt forced swim and tail suspension tests.
Materials and methods. The antidepressant activity of new 1,2,3-triazolo-1,4-benzodiazepine derivatives under the code MA-252, MA-253, MA-254, MA-255 and MA-261 was studied in the Porsolt forced swim and tail suspension tests. The following behavioral reactions, such as the latent period of the first immobility (more than 5 seconds), the total duration of immobility (staying in a stationary state), the number of immobile episodes, were recorded.
Results and discussion. During the study, a decrease in the total duration of immobility, the main indicator of “despair” of animals, and an increase in the latent period of the first immobility were monitored. It may indicate the manifestation of antidepressant properties of new 1,2,3-triazolo-1,4-benzodiazepine derivatives. The indicator of the antidepressant activity in groups of animals administered MA-253, MA-254 and MA-255 derivatives in all doses was higher among the groups studied. The depression index was the lowest when MA-253 and MA-254 derivatives were used in the dose of 1 mg/kg, and was not statistically significantly different from that in the group receiving imipramine in the dose of 25 mg/kg. According to the results of the tail suspension test, 1,2,3-triazolo-1,4-benzodiazepine derivatives MA-253, MA-254 and MA-255 showed a significant decrease in the total duration of immobilization by 69.4 %, 47.1 % and 33.1 %, respectively, in relation to the control group (p<0.05), as well as an increase in the latent period of the onset of the first immobility episode by several times.
Conclusions. A decrease in the duration of immobility in mice injected with 1,2,3-triazolo-1,4-benzodiazepine derivatives gives grounds to draw a conclusion that animals develop a state of “behavioral despair” and exhibit antidepressant properties.
A Survey Study on Proposed Solutions for Imbalanced Big Data
Authors: Razoqi Shaymaa Ahmed , Al-Talib Ghayda A.A.
Published: March 2024

Learning from imbalanced data has been a focus of studies for more than two decades of continuous development. Training data is considered imbalanced when the size of the positive (minority) class is neglected because of the large size of the negative (majority) class, in addition to the problem of deviating distributions of binary tasks. The appearance of big data brings new problems and challenges to the imbalance problem. Big Data announces the challenges with 5V: volume, velocity, veracity, value, and variety. This study relied on dividing the solution to the problem of data imbalance into three levels: data level, algorithm level, and hybrid approaches. First, the standard solutions for this problem that were proposed were mentioned, and in addition, the most important metrics adopted for measuring the classification efficiency of imbalanced data were identified. In this survey study, 27 studies were reviewed during the period 2015–2022, distributed according to the levels of treatment of the imbalance problem. They also reviewed the performance metrics that were used in these studies and the sources of the datasets to which these solutions were applied. The study makes it easier for researchers and scholars to see the solutions to addressing the problem of data imbalance and the hybrid approaches recently used for that, and to take advantage of them in improving the classification process.
Kriminologinen kirjasto vankeinhoidon tiedon välittäjänä
Authors: Kylkisalo Hannu
Published: April 2024

Mikäli tarvitset vankeinhoitoon ja kriminologiaan liittyvää kirjallisuutta, kannattaa suunnaksi ottaa Tikkurilassa sijaitseva Kriminologinen kirjasto. Rikosseuraamusalan koulutuskeskuksen yhteydessä toimiva erikoiskirjasto tarjoaa monipuolisen valikoiman kirjallisuutta kaikille kiinnostuneille.
Kinetics of IgM, IgA, IgG to SARS-CoV-2 in children with COVID-19 in Lviv region in different periods of the infectious process depending on the severity of the course and age
Authors: Stasiv Maria
Published: April 2024

Aim. The research aims at analyzing the kinetics of IgA, IgM, and IgG to SARS-CoV-2 in children based on the severity of COVID-19 and age.
Materials and Methods. The conducted prospective study involved 88 children (mean age 9.4 years) with COVID-19, admitted to the "Lviv Regional Pediatric Clinical Hospital "OKHMATDYT" from 2020 to 2021. The participants included 36 males (40.90%), and 52 females (59.10%) in the observation group. Diagnosis verification relied on clinical manifestations of the disease, with the detection of SARS-CoV-2 RNA from nasal mucus using the PCR method. The values of IgA, IgM, and IgG to S and N proteins of SARS-CoV-2, determined by the ELISA method at different times of the infectious process in 380 blood serum samples, were analyzed.
Results and Discussion.The research findings of IgM to SARS-CoV-2 in the first week of illness revealed a median value of 0.24 [0.14; 1.39], increasing to 0.49 [0.30; 2.87] in the second week. The highest median value of IgA to SARS-CoV-2 is 0.33 [0.24; 1.00] was found from 15 to 30 days, after 30 days it was 0.24 [0.20; 0.28].
The increase in the median value of IgG-N to SARS-CoV-2 was observed from the second week of the illness, reaching 1.13 [0.52; 3.17], with its maximum value at 5.68 [2.39; 8.86] within the period up to three months. Severe COVID-19 was diagnosed in 27 children (30.68%), comprising 15 females (55.56%) and 12 males (44.44%). In the majority of hospitalized children, IgM values at different degrees of disease severity were positive from the first to the seventh day of illness. In children with a severe course of SARS-CoV-2, the median value of IgM in blood serum during this period was 1.39 [1.36; 4.07]. There was a statistically significant difference between the IgG levels for moderate and severe forms on days 15-30 of the illness: 0.54 [0.21; 1.89] compared to 5.55 [4.99; 5.80], respectively (p<0.05). In patients with both moderate and severe forms of the disease, median values of IgG to N SARS-CoV-2 were positive throughout the study period. A significant increase in the median value of IgG to N SARS-CoV-2 was observed in females from day 31 to day 90. In severe cases of the disease, the median value of IgG to SARS-CoV-2 from three to six months was 9.40 [7.80; 10.60], which was higher than in patients with a moderate form of the disease - 8.72 [8.64; 8.97] (p<0.05).
Conclusions. Serological studies enable the investigation of the immune response to SARS-CoV-2, determination of seroconversion, and characterization of the course of COVID-19, being crucial for epidemiological research. The levels of IgM, IgA, and IgG to SARS-CoV-2 depend on the disease's severity and the patient's age.
ASPEK YURIDIS KEPEMILIKAN KONDOTEL SWISS BELHOTEL TUBAN – KUTA BALI OLEH WARGA NEGARA ASING BERDASARKAN PP NO. 103 TAHUN 2015
Authors: Nastasha Estherina. G  , Setiawati Anda
Published: April 2024

If previously the apartments were only meant for domestic use, they are now also utilized for non-residential uses, such as service hotels, one of which is situated in Bali, namely the Swiss Belhotel Tuban - Kuta Bali Condotel, whose existence draws tourists from abroad. According to PP No. 103 of 2015 concerning Ownership of Residential or Residential Houses by Foreigners Domiciled in Indonesia, the foreigner must be domiciled in Indonesia, provide economic benefits and the condotel purchased must be a new unit and built on Land Right to Use in order to be able to own and control the Swiss Belhotel Tuban - Kuta Bali Condotel unit. Simply said, there is a violation in the condotel unit's ownership Condotel ownership is given with a "strata title certificate" that includes 14 units that are owned and controlled by foreigners, in accordance with the provisions of PP No. 103/2015 and UURS. Given that the condotel is constructed on land with usage rights, foreigners should have ownership rights over flat units (HMSRS) rather than a "strata title" for their unit.
PEMBATALAN PERKAWINAN AKIBAT WALI NIKAH TIDAK SAH
Authors: Saarah Faadhilah  , Setyaningsih Setyaningsih
Published: April 2024

Humans usually have the desire to have a life partner and offspring, one way to make this happen is through marriage. In carrying out a marriage, sometimes unwanted things occur, to overcome them, one can do this, namely by submitting an application for annulment of the marriage to the court. Therefore, this issue is raised to answer the main issues, 1) What are the legal consequences for the cancellation of marriages due to illegal marriage guardians according to the laws and regulations in Indonesia? 2) Does the content of the judge's legal considerations in the Decision of the Central Jakarta Religious Court Number 193/Pdt.G/2019/Pa.JP comply with the laws and regulations in Indonesia? So this research was conducted normatively. The nature of the analytical descriptive research. How to draw conclusions with deductive logic. With data management, namely qualitative. The results of this study with reference to Article 28 of Law no. 1 of 1974 concerning Marriage jo. Article 75 Compilation of Islamic Law.
EKSEKUSI HAK TANGGUNGAN DI BANK SYARIAH (STUDI KASUS PUTUSAN NOMOR 5530/PDT.G/2017/PA.BADG)
Authors: Widodo Syifa Esthiningtyas Putri , Setyorini Dyah
Published: April 2024

The Mortgage Law and Objects Related to Land, namely Law Number 4 of 1996, (hereinafter reffered as the Mortgage Law) states that there are three ways if the debtor breaks a promise (wanprestasi) and the creditor can carry out the execution of the Mortgage object. The three methods consist of Parate Execution as stated in the Mortgage Law Article 6, Executorial Title as stated in the Mortgage Law Article 14 paragraphs (2) and (3), as well as Underhand Execution. Execution of Mortgage carried out by Islamic Banks in the Study of Decision Number 5530/Pdt.G/2017/PA.Badg remains subject to the Mortgage Law and the auction process which is carried out on the basis of Minister of Finance Regulation Number 27/PMK.06/2016 concerning The Instructions for Auction has been amended by The Minister of Finance Regulation Number 213/PMK.06/2020 concerning Instructions for Auction Implementation. The judge's considerations in adjudicating the Decision Number 5530/Pdt.G/2017/PA.Badg case are in accordance with the Mortgage Law, especially in Article 6 with the creditor still having the right to carry out execution through auction according to Minister of Finance Regulation Number 27/PMK. 06/2016 which has now been amended by Minister of Finance Regulation Number 213/PMK.06/2020.