bluuebunny/crossref_metadata_2025 huggingface dataset:
Monitoring Cytokine Levels in COVID-19 Overexposed and Vaccinated Volunteers
Authors: Briukhova D. D. , Dubrovina V. I. , Kiseleva N. O. , Korytov K. M. , Pyatidesyatnikova A. B. , Vishnyakov V. A. , Balakhonov S. V.
Published: November 2023

Relevance. COVID-19 is accompanied by high production of cytokines - immune molecules, imbalanced regulation of which leads to disruption of the immune response. Therefore, the study of cytokine status in both vaccinated and re-vaccinated patients is necessary to develop an immunoprophylaxis strategy for COVID-19. Aim. To evaluate the cytokine status in COVID-19 survivors and vaccinated employees of a health care facility against this disease. Materials and Methods. Production levels of cytokines (IL-4, IL-10, IFN-γ and TNF-α) were determined by quantitative enzyme immunoassay in serum of 144 volunteers. Results and discussion. A significant 1.5-fold increase in IL-10 and 2.0-fold increase in TNF-α was found in the group of re-invaccinated overinfected volunteers, and a 2.0-fold decrease in IL-4 compared with the vaccinated group. An inverse correlation between IL-4 and IFN-γ levels and timing after the disease was detected. A significant decrease in IL-4 in survivors (Omicron variant) and an increase in IL-10 in the survivors at the beginning of the pandemic as compared to other re-vaccinees was established. In the vaccinated group, regardless of the vaccine used, IL-10 and TNF-α decreased significantly after revaccination. No statistically significant differences were found between the cytokine status parameters in the survivors before and after vaccination. The predominance of the cellular component of immunity was established in all the examined groups, and the highest proportion of persons with a humoral immune response was detected among the vaccinated volunteers, while the highest proportion of persons with a mixed immune response was detected among the overexperienced non-vaccinated patients. Conclusions. The results obtained supplement the available data on coronavirus infection and indicate the need for further research.
Vaccination of Persons Subject to Call-up for Military Service
Authors: Kostinov M. P. , Zverev V. V. , Svitich O. A. , Mukhachev I. S.
Published: November 2023

Relevance. In recent years, there has been an increase in the incidence of a number of vaccine-preventable diseases. The health of military personnel directly affects the combat effectiveness of the army. Aim. Preserving the health of the military and ensuring the sanitary and epidemiological well-being of the troops is one of the most important tasks. Result. Approaches to vaccination of persons subject to conscription for military service and a list of infections against which they should be vaccinated (influenza, meningococcal and pneumococcal infections, chickenpox, COVID-19) are presented. Vaccines, schedule and features of vaccine administration are described. A list of the main regulatory documents for vaccination is provided. Conclusion. Vaccine prevention of persons subject to conscription for military service is an important strategic task, the implementation of which depends on coordinated work between military and civilian healthcare. Vaccination coverage of persons subject to conscription for military service must reach 100%.
The Incidence of Measles Infection in Southern Vietnam during COVID-19 Pandemic
Authors: Hoang M. , Antipova A. Yu. , Lavrentieva I. N. , Zarubaev V. V.
Published: November 2023

The paper presents data on measles cases identified in 18 provinces of South Vietnam (SV) in 2020, during the active phase of the pandemic of the new coronavirus SARS-CoV2. The measles virus actively circulated in SV in the first months of 2020: the average measles incidence rate was 1.27 per 100,000 population. Children under 5 years of age dominated in the age structure (71%). The vast majority of cases are people who have not been vaccinated against measles, as well as people who do not have information about vaccinations; in total, their share was 97.4%, but there were vaccinated and revaccinated individuals among the sick. Significantly more often, IgM-measles antibodies were recorded in samples obtained from the city of Can Tho, (n=57) where the infectious diseases hospital is located, receiving patients from neighboring regions of the SV. The largest number of measles cases were also recorded in the provinces of Dong Thap (n=57), Hao Glang (n=62) and Ho Chi Minh City (n=15). That is, residents of large cities, industrial and the medical centers were primarily involved in the measles epidemic process. A sharp decrease in the incidence of measles has been shown since April 2020, when measures to limit the spread of COVID-19 were introduced in SV. It should be noted that violations of vaccination associated with the COVID-19 pandemic, after the lifting of sanitary and epidemiological restrictions, may lead to increased morbidity and the development of measles outbreaks in Vietnam and other countries involved in the pandemic. Therefore, preventing future outbreaks will require strengthening measles surveillance and control measures to achieve its elimination.
Evaluación de la contribución del programa Ko’one’ex Kanik Maaya al aprendizaje de la lengua Maya
Authors: Caamal Chan Celsa Dolores , García Domínguez Luis Alberto
Published: November 2023

El presente estudio tuvo como sustento la importancia de la lengua maya en el ámbito educativo y una de las acciones que se han llevado a cabo para su revitalización lingüística en contextos urbanos. El objetivo consistió en evaluar la contribución del enfoque comunicativo al aprendizaje de la lengua maya como segunda lengua, con base en el programa Ko’one’ex Kanik Maaya (Aprendamos maya) en alumnos de sexto grado de una Escuela Primaria perteneciente al Sistema General, ubicada en la ciudad de Mérida, Yucatán. A través de una metodología mixta, se analizaron las habilidades lingüísticas y se recopilaron percepciones de alumnos, padres, docente y director escolar. De acuerdo con los resultados, los alumnos beneficiarios, alcanzan un nivel básico de aprendizaje, al comprender, responder, leer y escribir frases comunes y cotidianas de su contexto, lo que llevó a concluir que existe un logro significativo en el aprendizaje de la lengua maya. Sin embargo, se identificaron áreas de mejora. Este estudio subraya la importancia de preservar lenguas indígenas en contextos urbanos y demuestra que el enfoque comunicativo es efectivo.
CREATION OF THE RESIT INFORMATION SYSTEM FOR PREDICTION OF RIVER POLLUTION UNDER EMERGENCY SITUATIONS
Authors:   State University of Telecommunications, Kyiv, Gertsiuk M. M.
Published: November 2023

This article describes developed RESit information system, that created, as improvement to RESit software. System parts are described, such as database, server, interaction between server and possible water flow measurement sensors, learning utility, administration application and user application. RESit advantages are given in relation to using similar systems possibility in emergencies. A practical implementation of such developed methods is described: • pollution forecasting results adjusting method based on a neural network working based on the regression problem; • pollution level forecasting method between specific points using interpolation and recursion methods; • pollution source determining method based on a filtering and sorting algorithm that works on the basis of facts database; • system information with sensors measuring current water flow interaction mechanism. Thus, an information system acquires information technology for forecasting river pollution in emergencies features.
NETWORK MONITORING TOOLS IN IOT INFRASTRUCTURE WITH HYBRID ARCHITECTURE
Authors:   National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, Kyiv, Kaplunov A. V.
Published: November 2023

Text of annotation translation. – The processes of data exchange in computer networks have been examined within the context of generating productivity issues and critical network state in complex IoT systems with distributed infrastructure. Monitoring tools for computer network infrastructure in real-time were proposed for IoT systems. The architecture of a network environment monitoring system was developed to implement the concept of hybrid IoT infrastructure which was built with edge computing technologies. Also was proposed the methodology for integrating modern network infrastructure monitoring tools. The developed tools facilitate the collection, analysis and planning of performance components of IoT devices and their network environments. It enables the monitoring and prevention of critical states within the network IoT infrastructure in hybrid IoT system architectures. The proposed method for analysing computer network performance based on a weighted performance metric contributes to enhancing the efficiency of computer network monitoring within the local domain of network IoT infrastructure by load balancing. The developed tools was realized at the IoT edge, enhancing overall network monitoring efficiency at the local level and possessing the potential for integration with cloud technologies and services.
MODELS FOR ENHANCED PROTECTION OF PERSONAL DATA OF USERS OF THE DISTANCE LEARNING SYSTEM OF THE ARMED FORCES OF UKRAINE
Authors:   State University of Telecommunications, Kyiv, Shapran O. O.
Published: November 2023

The problem of improving existing and developing new models and methods of increasing the security of personal data of users of the distance learning system of the Armed Forces of Ukraine based on artificial intelligence is substantiated. It has been proven that to ensure a high level of security of personal data of users of distance learning systems in modern conditions, progressive organizational, hardware and software solutions are actively used. An analysis of foreign and domestic experience in the development and implementation of personal data protection systems for users of the distance learning system is provided, and a conclusion is made about the possibility of significantly increasing their efficiency due to the development of mathematical and software. It is justified that the most relevant in this direction is the use of models and methods of artificial intelligence, namely, fuzzy logic and hybrid networks. Research materials are presented on the development of a methodology for improving the security of personal data of users of the distance learning system of the Armed Forces of Ukraine, which provides an effective response to the flow of threats and is based on the implementation of models and methods of fuzzy logic and hybrid networks; the model for determining the state of the personal data protection system and the method of forecasting the state of the personal data protection system are described. The results of computer modeling are presented.
USING SLURM WORKLOAD MANAGER FOR MANAGING SUPERCOMPUTERS AND LINUX CLUSTERS
Authors:   State University of Telecommunications, Kyiv, Dryha V. O.
Published: November 2023

The article is dedicated to the use of the Slurm Workload Manager for managing supercomputers and Linux clusters and highlighting the importance and advantages of using the Slurm Workload Manager in resource management on multi-user systems. Within the research, existing workload management systems and their limitations were analyzed. Based on this analysis, it was found that Slurm is one of the most widely used and efficient solutions in the field of resource management on multi-user systems. The article provides a detailed examination of the functionality of Slurm, including its core functions such as resource scheduling, task distribution, and system monitoring. Slurm allows users to efficiently utilize computational resources, distribute tasks among cluster nodes, ensure optimal CPU time usage, and control the system load. These features enable high productivity and efficiency in resource utilization. The advantages of Slurm compared to other resource management systems are presented in the article. Slurm is noted for its flexibility and the ability to configure various types of resources, as well as support for different scheduling algorithms. Limitations and challenges associated with using Slurm are also mentioned, providing readers with a comprehensive understanding of its capabilities and potential considerations for implementation. This article will provide readers with a detailed overview of the Slurm Workload Manager, its core functions, advantages, and limitations. With the comprehensive analysis and description of Slurm's core functions, the article will serve as an invaluable source of information for professionals working with large-scale computing clusters and supercomputers. It will also be beneficial for those interested in exploring best practices in resource management on multi-user systems and learning effective strategies for utilizing the Slurm Workload Manager.
On The Balance of the Federal Budget: Conceptual Ideas and Russian Experience
Authors: Sukharev Aleksander
Published: November 2023

The models of balancing the federal budget within the framework of changes in the external economic situation and the experience of its implementation in Russia are considered. Approaches to assessing the solvency of the state to fulfill its monetary obligations are shown.
Economic Inactivity and Assessment of the Economic Burden of the Population in the Regions of Russia
Authors: Nanavyan Ashkhen
Published: November 2023

The article presents an analysis of the dynamics of the number of persons outside the labour force, the calculated economic burden of the population and the economic burden of the employed in some CIS countries and in the regions of the Russian Federation. In the CIS countries, the greatest economic burden was once observed in Armenia, although in subsequent years it significantly decreased, as a result of reduction in the unemployment rate. The trend of reducing the economic burden in Uzbekistan and the relatively stable situation in Kazakhstan are noted. In the Russian Federation, the economic burden of the population has been decreasing, but significant regional differentiation remains. The minimum values of the economic burden are noted in the Chukotka and Yamalo-Nenets districts, in the Magadan region, and the maximum values are in the Republic of Adygea and in the Kurgan region.
The Resource Potential of the State Pension System and Related Social Services as an Object of Research
Authors: Eduard Vafin
Published: November 2023

The article examines the theoretical foundations of the formation of resource potential and gives its characteristics as an object of research. It is noted that the functioning of the current pension system results in a shortage of financial resources, significantly reduces the opportunities for the development of the market of high-quality pension and social services. The concept of "resource potential of the pension system" is defined through the legal, social and economic content of its characteristics. The elemental structure of the resource potential and its probabilistic nature are considered. The necessity of using a set of systemic and integrated approaches in the study of the financial potential of the pension system is substantiated. Recommendations for improving the use of the resource potential are proposed.
Optimizing Provision Management for Socially Oriented Non-Profit Organizations in Russia
Authors: Morozova Irina
Published: November 2023

The article discusses the current state of the sector of socially oriented non-profit organizations (SONPO) of the Russian Federation in the context of federal districts. There is an asymmetry in the distribution of resources, which entails a significant backlog of some federal districts in terms of SONPO development. The formation of a mechanism for interaction between the state, society, business and socially oriented non-profit organizations is considered as a key measure for optimizing the financial and property support of SONPO activities. The proposed mechanism is based on the creation of special funds in each of the Russian regions to ensure the activities of socially oriented non-profit organizations.
Actual Vectors of the Transfoemation of Russian Businesses within the Framework of Sustainable Development Strategy (ESG Standards)
Authors: Abdullina Leila
Published: November 2023

The authors analyze the historical context and relevance of sustainable development indicators and offer an overview of business transformation trends in Russia in line with ESG standards. The article considers environmental, social and managerial trends in the transformation of business in the Russian Federation, highlights promising areas, problems and limitations. Specific examples of initiatives and achievements in line with the ESG principles from various leading companies in Russia are given. The authors suggest that companies pay attention to the prospects for integrating sustainable development principles into corporate strategies and promote the development of social programs to support employees.
On Factors Threatening the Economic Security of Light Industry Enterprises
Authors: Bayboboeva Firuza
Published: November 2023

The factors that threaten the economic security of light industry enterprises are highlighted in the article. The author refers to such critical problems as long-term shortage of locally produced items that meet consumers’ taste and demand for fashionable goods. It is emphasized, that such shortages contribute to the development of preferences for imported goods which is not easy to overcome.
Predicting Novatek Share Prices Using the Models of Decision Tree and Linear Regression
Authors: Kuznecov Roman
Published: November 2023

The development of technology and the emergence of various machine learning models influence social life in many ways, including the analysis and forecasting of the stock market. The ability to competently select and use machine learning models in predicting stock quotes is one of the key competitive advantages that allow large investment companies and individuals to increase their profits from the market activity. The study reveals the effectiveness of using decision tree and linear regression models in predicting daily quotes of NOVATEK.
MEDIA SOSIAL UNTUK PEMBELAJARAN DALAM MENDORONG DIGITALISASI PADA MASYARAKAT 5.0 BAGI MAHASISWA PEMBELAJARAN JARAK JAUH
Authors: Sela Shiyrah Theosebes , Paulina Christine
Published: November 2023

Penggunaan media sosial untuk berbagai tujuan seharusnya lebih sederhana, lebih murah namun lebih bermanfaat. Penelitian ini mengkaji penggunaan media sosial untuk pembelajaran dengan mendorong digitalisasi pada masyarakat 5.0. Untuk pengumpulan data, kuesioner telah dibagikan secara luas dan dikirimkan ke mahasiswa pembelajaran jarak jauh melalui formular Microsoft Forms. Penelitian ini menggunakan metode gabungan dengan menggunakan metode kuantitaif untuk pengolahan data dan kualitatif untuk menganalisa hasil untuk mendapatkan temuan bagi pertanyaan penelitian sebagai berikut: (1) Bagaimana media sosial mendukung pembelajaran?, (2) Berapa lama dalam sehari orang saling terhubung melalui media sosial?, ( 3) Bagaimana media sosial mendukung masyarakat dalam mendorong digitalisasi?, (4) Bagaimana seharusnya pembelajaran yang dilakukan dalam digitalisasi menuju masyarakat 5.0. Penelitian ini terbatas pada lingkup perguruan tinggi pembelajaran jarak jauh dan seharusnya dapat diaplikasikan pada organisasi Pendidikan lainnya untuk penelitian selanjutnya.
PENGARUH GOOD CORPORATE GOVERNANCE TERHADAP KINERJA KEUANGAN PADA PERUSAHAAN PERTAMBANGAN YANG TERDAFTAR DI BEI
Authors: Arimby Rista , Astuti Tutut Dewi
Published: November 2023

Keberhasilan perusahaan dalam meningkatkan kesejahteraan para pemegang saham menjadi salah satu faktor penunjang bagi perusahaan dalam meningkatkan kinerja keuangan perusahaannya. Salah satu faktor yang mempengaruhi kinerja keuangan adalah Corporate Governance yang dapat diukur menggunakan rasio profitabilitas, yaitu Return On Assets (ROA). Penelitian ini bertujuan untuk mengetahui pengaruh Good Corporate Governance yang diproksikan pada kepemilikan institusional, dewan komisaris independen, dan komite audit terhadap kinerja keuangan perusahaan pertambangan yang terdaftar di Bursa Efek Indonesia periode tahun 2020-2022. Sampel dalam penelitian ini berjumlah 45 sampel yang berasal dari 15 perusahaan pertambangan yang diseleksi sesuai dengan kriteria purposive sampling yang telah ditentukan. Metode analisis data yang digunakan adalah analisis regresi linier berganda dan uji t yang dibantu dengan SPSS versi 21. Hasil dari penelitian ini menunjukkan bahwa kepemilikan institusional dan dewan komisaris independen tidak berpengaruh terhadap kinerja keuangan, sedangkan komite audit berpengaruh terhadap kinerja keuangan.
P53 Expression in Gastric Dysplasia and carcinoma in Erbil City
Authors: Al-Badri Bayan A. , Qadir Ali Gayllan
Published: November 2023

Background: Alteration in the expression of p53 tumor-suppressor protein is an event that occurs frequently in human cancer, but the practical implications of this phenomenon are yet to be fully exploited.Objectives: to determine the value of p53 expression as a marker of tumor aggressiveness and the relationship between p53 over expression and clinico-pathologic variables in gastric adenocarcinoma.Material & Methods: The expression of p53 was studied immunohisto-chemically in 10 cases with gastric dysplasia and 85 cases with gastric adenocarcinomas using formalin fixed, paraffin-embedded tissue samples. D07 a monoclonal antibody to p53 protein was used for the immunehistochemical analysis. The correlation between p53 expression in gastric dysplasia, gastric adenocarcinoma and clinicopathologic variables were analyzed.Results: P53 positivity was found in 48.2% of gastric carcinoma cases, and 40% of gastric dysplasia. There was a significant correlation between the rate of p53 over expression and tumor grade (p = 0.015), and also with carcinomas associated with lymph node involvement (p = 0034). There was no significant association between p53 protein expression and histological type (p = 0.171). The association between p53 protein expression and the depth of tumour invasion was found to be statistically insignificant.Conclusion: The results obtained suggest that P53 protein expression is a useful biomarker for the assessment of gastric adenocarcinoma aggressiveness. The preoperative assessment of p53 expression in gastric carcinomas can be helpful in identifying patients with higher grades and more advanced tumors. P53 immunoreactivity can predict lymph node status in patients with gastric carcinoma.
High Expression of P53 protein in Recurrent Pregnancy Loss Could Play a Role in the Pathology!!
Authors: Abdul-Mohaymen Nidhal , Al-Obaidi Asmaa’ B. , Rasheed Thanaa
Published: November 2023

Background: Recent data provide evidence that p53 plays a critical role in mediating pregnancy by regulating steroid hormone activationObjective: localization of semi quantitation tof por protein at the materno-fetal interface, in patients with recurrent pregnancy loss.Methods: Immunohistochemistry analysis of p53 protein using paraffin embedded sections of curate samples obtained from 40 women, who where divided into three groups: 24 women with RPL, 10 women with abortion for the first time, and 6 women with induced abortion.Results: The mean value of the expression of p53 protein in the RPL group was (65.8±2.16), which is significantly higher than that of the second group (48.0±2.81), and the third group (50.0±4.66), (p=0.000).Conclusion: High expression of p53 protein in women with RPL may have a role in accelerating placental apoptosis leading to failure of pregnancy.
Production as a link in the market of agricultural machinery for crop farming in Ukraine
Authors: Navrotskyi Yaroslav , Petrov Vadym
Published: November 2023

The production of agricultural machinery and equipment in Ukraine is one of the main sources of supplying the market with resources and facilities for agricultural production, but as of 2023, it does not fully meet its needs. According to the relevance of the subject matter, the purpose of the study was to investigate the trends in the development of the agricultural engineering industry in Ukraine in dynamics, the impact of military operations on it, and to work out effective ways to overcome their negative consequences. The following methods were used: dialectical, statistical and economic, graphical, index, correlation and regression analysis, empirical, comparative analysis, analytical forecasting, abstract logical, etc. The principles of regional placement of agricultural engineering enterprises are defined, depending on the availability of raw materials, energy and labour resources. The structure of enterprises in the industry by category is determined – most of them are small enterprises (85.8-91.5%), but the majority are employed by medium-sized enterprises (59.1-79.3%). Due to military operations, the number of active enterprises in the industry has decreased by about 30 units. The trend of reducing the production of tractors, combine harvesters, and some types of tillage machines in Ukraine and the reasons for its occurrence are revealed. The prospects of production of sowing equipment in Ukraine are substantiated. The index of identified comparative advantages of different countries by individual types of machinery is analysed, and it is found that in Ukraine only tillage machinery has a high level of advantages – 1.802 and has optimistic prospects for development. The paper defines a close correlation between the export and production of tractors in Ukraine in 2010-2021 (the corresponding correlation coefficient – 0.8982). Problems that hinder the development of the agricultural machinery industry are identified: inflation, disruption of logistics links and loss of suppliers, high prices for energy resources, etc. Recommendations for overcoming them are proposed: creating favourable investment conditions; implementing protectionist customs and tax policies for industry enterprises; evacuating them from the war zone. The proposed measures will contribute to the restoration, preservation, and progressive innovative development of the potential of agricultural engineering un Ukraine
Trends in the development of dairy farming and its state financial support in Ukraine
Authors: Tulush Leonid , Hryshchenko Olena , Strykhovskyi Dmytro
Published: November 2023

The importance of dairy farming for food security and the formation of added value in agriculture necessitates a rational combination of market self-regulation mechanisms and instruments of state intervention in economic processes in the sector. The purpose of this study was to assess the development of dairy farming in Ukraine and identify ways to improve its state support. The following methods of scientific cognition were employed in the study: analysis and synthesis, induction and deduction, abstract-logical, historical, comparative analysis, monographic, computational-constructive, graphical, tabular, statistical analysis, generalisation, causal and retrospective analysis, analytical alignment of time series, economic modelling, and forecasting. Based on the results of using these methods, the study summarised the current trends in the development of dairy farming in Ukraine and its state financial support using tax and budgetary regulation instruments. The study covered the specifics of the existing structure of dairy farming in Ukraine, which, unlike the countries of the European Union, is represented by three categories of economic entities. It was found that since the early 2010s, Ukraine has been experiencing processes of concentration in the field of dairy farming. The study found a direct correlation between the size of the number of cows kept and the profitability of dairy farming. It was determined that enterprises with up to 100 cows gradually reduce the volume of activities in the dairy farming sector due to its unprofitability. The study assessed changes in the structure of dairy farms in European countries from the mid-1990s to the early 2020s and found that they are also characterised by trends in the concentration of dairy farming. The efficiency of the state financial support for the development of dairy cattle breeding in Ukraine through the instruments of tax and budgetary regulation in the pre-war period and in the martial law regime was assessed. The paper described the advantages and disadvantages of the applied instruments of budgetary support for dairy farming, substantiated proposals for the use of instruments of tax and budgetary stimulation of dairy farming development in the period of post-war economic recovery of Ukraine, considering the existing trends in the development of dairy farming in Ukraine. The practical significance of this study lies in the possibility of using the obtained results in the drafting of policy documents on the post-war development of the agro-industrial complex of Ukraine in general and specifically its dairy subcomplex
Regional aspect of the efficiency of lending to the agricultural sector of the Ukrainian economy
Authors: Cheremisina Svitlana , Tomashuk Iryna
Published: November 2023

Ukrainian agriculture has shown resilience, adaptability, and production flexibility during the war. At the same time, the priority issues are the lack of financial resources for business operations, the restoration of damaged facilities and ensuring technological discipline. In this context, the issue of lending to agricultural enterprises is of great relevance. The purpose of this study was to improve and develop methodological tools for assessing the credit burden and efficiency of lending in agriculture by region of Ukraine. The study employed several methods of cognition: comparative analysis, tabular, graphical, statistical, computational-constructive, abstract-logical. In 2015-2022, lending to agricultural producers increased by 2.4 times (by 43.5% or UAH 35.9 billion in 2022 alone). The share of loans attracted is dominated by Kyiv Oblast (31%). The share of lending to the agricultural sector increased by 2.6 times (from 6.1% to 15.7%). Ukrainian agrarians are lent mainly in the national currency (76.4% of disbursed loans) and for terms up to one year (54.4%), with terms of 1 to 5 years (41.2%). In 2015-2021, the loan burden per business entity and per employee almost doubled. The highest lending efficiency was demonstrated by farms in Zakarpattia, Zhytomyr, Rivne, Luhansk, and Chernivtsi oblasts. During the first year of the full-scale war, the efficiency of lending in agriculture fell by 48% (from 8.63 to 4.49 thousand UAH). Agricultural enterprises need support from both the state and credit institutions. The practical significance of this study is determined by the improvement of tools for measuring the level of credit burden and assessing the effectiveness of lending in the agricultural sector of the economy by regions of Ukraine, which can be used by public and sectoral authorities in the regional practice of monitoring and intensifying the practice of state financial support for rural producers
Introduction to Evolutionary Cancer Cell Biology (ECCB) and Ancestral Cancer Genomics
Authors: Niculescu Vladimir F.
Published: November 2023

Cancer is a complex and devastating disease that has engaged scientists and researchers for decades. Despite tremendous efforts, previous hypotheses about cancer development have not achieved significant breakthroughs. Evolutionary Cancer Cell Biology (ECCB) is a novel and emerging branch of oncological science that provides an evolutionary perspective on the origin of cancer. It reveals that the cancer genome evolved hundreds of millions of years ago, long before the multicellular organisms such as metazoans and humans emerged (1,2,3). ECCB aims to unify all evolutionary insights, hypotheses, and theories into a cohesive framework. It investigates the intricate relationship between cancer genomics and ancient pre-metazoan genes that emerge when normal cells transform into cancer cells. It challenges conventional wisdom of cancer research by suggesting that cancer could arise through intrinsic cellular mechanisms without genetic alterations and mutations (4). Furthermore, it postulates that somatic mutations are only secondary, downstream events in the process of oncogenesis.
A Study to Assess the Effect of Pelvic Floor Muscle Strengthening Exercises on Urinary Incontinence in Patients with Cervical Cancer Undergoing Radiation Therapy at a Tertiary Cancer Centre
Authors: Jagdiish Prathepa , Daptardar Anuradha
Published: November 2023

OBJECTIVES - The objective was to analyse the effect of pelvic floor muscle strengthening exercises on urinary incontinence in patients with cervical cancer undergoing radiation therapy at a tertiary cancer centre.

METHODS - This study included 45 cervical cancer patients undergoing radiation therapy, using a non-probability convenience sampling technique and a quasi-experimental one-group pre-post design. The intervention consisted of four pelvic floor muscle strengthening exercises including a) Kegel exercise, b) Squeeze and release, c) Pelvic floor/inner thigh ball squeeze, d) Lower trunk rotation / Lying hip rotation. These exercises were demonstrated with the help of a model pamphlet and were performed four times daily. The total duration of the four exercises was 18-20 minutes, over a period of 12 weeks. Daily follow-ups were conducted and a logbook was maintained for compliance. The patients were assessed for urinary incontinence using the ICIQ UI-SF tool and a perineometer on the 8th and 12th weeks. The statistical evaluation plan involved summarising the demographic and clinical data with descriptive statistics. The primary objectives were evaluated with the Friedman test and one-way ANOVA test, while the secondary objectives were evaluated with frequency distribution and chi-square t-test.

RESULTS OF THE STUDIES - In this study, 45 women received the intervention; however, only 43 women completed the intervention and follow-up.
The results showed that the frequency and quantity of urinary incontinence significantly reduced from the patient’s baseline parameters. It was observed that the participants’ ICIQ UI SF total score on the pre-test had a mean of 12.56 (SD±3.74), after 8 weeks of intervention the mean was 11.33 (SD±3.48), and after 12 weeks of intervention the mean was 8.86 (SD±2.97). The P-value was statistically significant (p <0.001). There was a significant (P <0.001) improvement in the quality of life of the participants. The research hypothesis was accepted. There was significant (p <0.001) alleviation in urinary incontinence after pelvic floor muscle strengthening exercises in patients with cervical cancer undergoing radiation therapy. The pelvic floor muscle contractility on the perineometer on pre-intervention had a mean of 21.63 (SD±2.71), after 8 weeks of intervention the mean was 22.33 (SD±2.65), and after 12 weeks the mean was 23.49 (SD±2.16). The pelvic floor muscle strengthening exercises statistically significantly (p <0.001) proved the improvement in pelvic floor muscle strength.

CONCLUSION - The results of this study suggest that pelvic floor muscle strengthening exercises were effective for alleviating urinary incontinence, which improved the quality of life of patients with cervical cancer undergoing radiation therapy. It is a statistically significant intervention.
Decoding Time Dynamics: The Crucial Role of Phase Shift Measurement amidst Relativistic & Non-Relativistic Influences
Authors: Thakur Soumendra Nath
Published: November 2023

This research endeavors to decode the intricate dynamics of time by shedding light on the pivotal role played by phase shift measurement amidst the influences of both relativistic and non-relativistic factors. Time, a fundamental dimension of existence, intertwines with the dynamic nature of waves, and this study explores the essentiality of measuring phase shifts in unraveling a universal phenomenon. Relativistic effects, such as speed and gravitational potential differences, alongside Newtonian influences like mechanical speed, contribute to the nuanced dance of waves. External elements, often overlooked, including heat, magnetic flux, and electromagnetic flux, further enrich the temporal tapestry. The relationship between wavelength distortion and time dynamics, expressed through λ∝T, forms the cornerstone of understanding, revealing how changes in wavelength correspond to shifts in the temporal domain. Crucially, amidst the tapestry of influences, the decisive factor for comprehending time dynamics is identified as the measurement of phase shift—in degrees. This metric consistently represents the corresponding time shift or time distortion, transcending specific external influences. The research provides universal insights into the dynamic interplay of relativistic and non-relativistic factors, offering a nuanced and comprehensive view of the temporal tapestry that envelops our existence.
Far-Field Accelerograms for Nonlinear Two-Dimensional Analysis of Steel Moment Frame
Authors: Hassani Sokhtesaraei M. , Ghassemieh M.
Published: November 2023

Due to destructive effects of earthquake loads, acceptable assessment of these loads and create a coordinated approach adapted to each seismic zone, is important. In this study, the main purpose is preparing an appropriate list of far field accelerograms for nonlinear two-dimensional analyses. The main focus of this study is to evaluate all parameters affecting on proper accelerogram selection. By considering 2000 accelerograms and all effective parameters include distance, magnitude, frequency content, earthquake mechanism, soil and properties of earth layers, a list of 20 accelerograms were presented for nonlinear two-dimensional analyses. These proposed accelerograms represent the actual ground motion as much as possible. Also, the study of final scale factor of accelerograms for steel moment frame have been obtained with point-to-point difference in periodic intervals corresponding to each frame method.
Developed Computational Methodology for the Most Effective Design of Open Channel Cross Sections
Authors: Abd-El-Baky Rania
Published: November 2023

Open channel is the most important way to convey water for various purposes. Channels cost a lot of money to construct. The optimal design means delivering water with efficiency, safely, and economical costs of construction. The determinant of minimum cost must take into account the effect of manning coefficient variation between the sides and the bed. The proposed program is solved using the Shuffled complex evolution method developed at the University of Arizona (SCE-UA) algorithm. The results obtained in this study are compared with existing models developed by others in the past using either the complex equations or the Simultaneous Perturbation Stochastic Approximation (SPSA) technique. The result shows that the existing optimization problem formulations, when solved using SCE-UA, provided results compared to those solved using the Lagrange multiplier method. The results obtained in this study indicate that approximately 34% of cost savings can be achieved. Also, the provided results were compared to those obtained by others in the past using (SPSA) technique. The results obtained in this study indicate that approximately 36.5% of cost savings can be achieved. It was found that the (SCE-UA) technique is more accurate than (SPSA) and has the lowest total construction cost.
What Are the Factors Influence on Construction Safety? A Review
Authors: Rashid Sheikh Azim Ur , Hadikusumo Bonaventura H W , Chowdhury Md. Rakibul Islam
Published: November 2023

Because of resource constraints, construction safety management is more difficult in underdeveloped nations. The aim of this paper is to explore and identify the key factors affecting construction site safety performance.  The first step in this study was a systematic assessment of 98 papers using a content qualitative approach. From this review, 12 influential factors for safety performance in construction projects were identified. Second, a framework was developed to illustrate the interactions between the identified factors at various project management levels. Furthermore, expert interviews were used to validate the framework. The findings of this study will help project managers better understand how different important safety issues at different construction project hierarchies affect the safety performance of the sites.
MENGGAGAS ETIKA DAKWAH DI RUANG MEDIA SOSIAL
Authors: Mastori Mastori , Islamy Athoillah
Published: November 2023

This study intends to explore various values ​​of Islamic teachings that can be used as a da'wah code of ethics in the social media space. This research is qualitative research in the form of library research. The main data sources used are various scientific literature, both in the form of books (books) and scientific journals related to the discussion of ethical values ​​in preaching on social media. Meanwhile, secondary research data sources used are various scientific literature relevant to the core object of this research. This research is categorized as conceptual research with a philosophical normative approach. Meanwhile, the nature of this research approach is descriptive-analytic. However, it is not only descriptive-analytic but also prescriptive. The results of the study show that there are various values ​​of Islamic teachings that can be used as ethical values ​​of indictment in the social media space (socmed). These ethical values ​​include being sincere and true, honest, and avoiding coachman debates
ANALISIS SEMIOTIKA IKLAN LAYANAN KELUARGA BERENCANA (KB) VERSI PERNIKAHAN DINI
Authors: Suryani Suryani , Suraili Suraili
Published: November 2023

Family Planning (KB) is one of the government programs aimed at limiting the number of children in a family and inhibiting the rate of population growth in Indonesia. To introduce the program, the government made an advertisement for KB service version of Early Marriage on television. These ads contain meanings that are indirectly conveyed through the symbols in the ad. The ad will be analyzed using Jurgen Ruesch's semiotic analysis model, classifying all verbal and nonverbal cues in sign language, action language and object language. The meaning of the symbol consisting of the language of the sign, the language of action and the language of the object that includes body communication such as gestures, facial communication, eyes and touch as well as space and time communication in the KB ad version of early marriage sends the message that early marriage is better avoided for the maturity and readiness of the couple in the household both mentally and physically.
PERAN DAN POLA INTERAKSI PESAN PADA AKUN MEDIA SOSIAL PEMKAB BANGKA
Authors: Iksander Iksander
Published: November 2023

The use of social media as part of e-government development for local governments is an obligation, especially related to the concept of online public relations for every institution in today's digital era. This research was aimed to describe the social media accounts owned by the Bangka Regency Government in supporting the presence of the official site bangka.go.id as well as to define what pattern of message interaction was among the social media accounts. Based on a descriptive analysis using the 7'cs Framework approach, this study found that social media accounts owned by the Bangka Regency Government were classified as non-existent. the second finding is that the message interaction can be classified as one-way patterns where one content on one platform is forwarded to another social media platform without any difference.
DESIMINASI DAKWAH Gus BAHA’ DAN ANTUSIASME NETIZEN DI MEDIA SOSIAL
Authors: Musyaffa Musyaffa
Published: November 2023

Muhammad Baha'udin Nursalim, Gus Baha' was named the Da'i of The Year 2020. During the Covid19 pandemic, the pattern and study of his da'wah communication also enlivened social media. How does Gus Baha' convey the message of da'wah on social media so that it attracts mad'u's attention? How does Mad'u respond to Gus Baha's da'wah style through social media? The author revealed the question by analyzing it through a qualitative approach and descriptive method. The author collects several data and fact findings from Instagram, Youtube, and Facebook which officially and authentically package their da'wah. The results of the study show that: First, Gus Baha' in preaching tends to be humorous, full of 'jokes' but full of Islamic scientific treasures. Comprehensive da'wah message with logic and scientific argumentation. He is Hafidz as well as mufassirin, making Gus Baha 'more flexible in conveying messages. Second, netizens or mad'u responded to Gus Baha's study with positive comments. Although, some mad'u often repeat the content in order to understand.
ANALISIS FRAMING GERAKAN SOSIAL AKSI CEPAT TANGGAP (ACT) DI MEDIA SOSIAL
Authors: Ahmad Rizal Derry , Nurhalim Muhsin , Avicenna M. Putra Yuniar , Rofiq Hosnor
Published: November 2023

As a humanitarian agency, Aksi Cepat Tanggap (ACT) utilizes social media to promote its activities as well as invite the audience to be involved by donating or volunteering. This research focuses on the social media content displayed so that the public can help each other. By using qualitative descriptive methods and using Norman Fairclough's theory of Critical Discourse Analysis, the results of this study suggest that the display of text, images, and discourses narrated by Aksi Cepat Tanggap (ACT) on social media is filled with experiential values, relational values, expressive values, and collective values ​​with strong Islamic nuances. The public's interpretation of texts and images is also reflected in the largest source of donations i.e. from the public.
PENERAPAN KOMUNIKASI MASSA TERHADAP BUDAYA MASYARAKAT PADA REMAJA DI ERA SOCIETY 5.0
Authors: Mustofa Muhammad Bisri , Wuryan Siti , Tari Iis Liana , Septiani Julisa , Andriyani Lisa
Published: November 2023

The condition of social media is now able to fully encourage social interaction and all community activities. The influence of mass communication (cognitive, affective, and behavioral) for users or social media audiences where their behavior has been positively and negatively influenced. This condition is very concerning because the socio-culture of teenagers has been influenced by the mass media which seems to have become the basic need of teenagers. The mass media should be consumed according to need, in fact now the mass media has become a basic need that has been able to fulfill and assist all daily activities. However, as a teenager in his time, he should still be controlled and need supervision. This study focuses on how the influence/effect of mass communication on audiences who use social media on teenagers in the 5.0 era of society. Adolescence is the start of the change between childhood and adulthood, which is still influenced by the mass media in this 5.0 era of society. Researchers used library research methods using various library sources or previously written works. From the results of this study, the greatest effect of social media on adolescents is a change in attitudes and behavior in the social and cultural sphere. Therefore, the social effects of mass communication on teenagers are like 2 sides of a coin that have good and bad effects, so due to the mass media today, everything that teenagers do sometimes cannot be controlled and still cannot be considered good or bad for themselves.