bluuebunny/crossref_metadata_2025 huggingface dataset:
Tardive transvaginal small bowel evisceration after colpohysterectomy: a case report of a rare surgical emergency
Authors: Bortolin Greta , Querini Giorgio , D'Ovidio Angelo , Bocca Gabriele , Zonta Sandro
Published: October 2023

Transvaginal small bowel evisceration is a rare surgical emergency after gynaecological surgery with around 100 cases described in literature from 1864. Its diagnosis is merely clinical. The surgical treatment is time-depending because of the risk of acute small bowel ischemia. A 71-year-old female presented in our emergency room complaining abdominal pain, vomiting, and small bowel evisceration through the vagina. She suffered gynaecological prolapse and underwent transvaginal hysterectomy four years earlier. At the clinical examination, intestinal loops were oedematous, dusky, vascular sufferance, and without peristalsis. An urgent laparotomy was performed to reduce the prolapsed bowel, resect the ischemic loop, and vaginal cuff closure. Transvaginal bowel evisceration is a delay complication after hysterectomy. It is a life-threatening condition that requires prompt recognition and surgical management.
Post-traumatic biliopleural fistula treated with endoscopic retrograde cholangiopancreatography: a case report
Authors: Bergna Alessandro , Salvetti Francesco , Leati Giovanni , Monti Marco , Segalini Edoardo
Published: October 2023

Thoracobiliary fistulae are a rare disorder caused by iatrogenic injury or trauma. Because these fistulae are uncommon, no standard of care has been established, but non-operative management (NOM) is often advised. As a result, endoscopic retrograde cholangiopancreatography (ERCP) appears to be playing a growing role in the treatment of select cases. A 42-year-old male patient involved in a street fight developed a biliopleural fistula as a result of an abdominal penetrating injury. Even in the lack of a clearly defined site of biliary leak, NOM and ERCP have proven to be safe and effective therapy in this case.
Rare but possible: clopidogrel-induced pancytopenia
Authors: Bocchi Pietro , Giuri Pasquale Gianluca , Bovino Achiropita , Casola Alessia , Detrenis Simona , Bertorelli Marcello , Meschi Michele , Mangè Giancarlo
Published: October 2023

We present the case of an 84-year-old female patient admitted to the Internal Medicine Ward for atypical chest pain and laboratory findings of severe pancytopenia. Past medical history was remarkable for an episode of myocardial infarction approximately 4 weeks prior to the current hospitalization which had required angioplasty + drug-eluting stent and dual antiplatelet therapy with acetylsalicylic acid and clopidogrel. Some rare cases of clopidogrel-induced pancytopenia are described in scientific literature, therefore, after excluding infectious, vitamin deficiencies, and autoimmune causes, we modified the antiplatelet therapy by replacing clopidogrel with ticagrelor, obtaining complete leukocyte recovery within a few days. Since clopidogrel is an antiplatelet drug still used in clinical cardiological practice, the knowledge of this rare side effect may lead the clinician to suspect hematological toxicity which, if recognized promptly, may suggest modification of antiplatelet therapy and limit any possible infectious complications for the care of the patient.
Design and operational parameters optimisation of a citrus substrate filling and transporting machine
Authors: Xu Qinchao , Li Shanjun , Pan Haibing , Yang Qian , Zhang Jian , Lu Xuedong , Shan Cheng
Published: October 2023

Aiming to address the problem of low mechanisation of filling and transporting citrus seedling pots in China, a new type of pot filling and transporting machine with 120 pots at a time was designed. Based on the study of flow characteristics of the seedling substrate, key components of the filling and transporting machines, such as the hopper component, transmission mechanism, flip mechanism, and steering mechanism, were designed. The effects of the opening width of the hopper, the rotating speed of the stirring shaft, the moisture content of the seedling substrate, and the forward speed of the transporting device on the filling effect of the seedling pot were studied by the experimental method, and the optimal operation parameters were determined. The prototype tests were repeated 3 times with the best combination of parameters. The test results indicate that the machine was in good condition for loading and unloading. The number of filling pots was 120 once, and the average filling time was 40 s. The average filling mass was 1.881 kg, 0.006 kg different from the predicted value of 1.887 kg, and the relative error was 0.32%. The coefficient of variation of the mass was 2.97%, which was 0.12% different from the predicted value of 2.85%, and the relative error was 4.0%. This designed machine can provide a reference for developing and optimising the citrus substrate filling and transporting machine.
Centro-affine differential geometry and the log-Minkowski problem
Authors: Milman Emanuel
Published: October 2023

We interpret the log-Brunn–Minkowski conjecture of Böröczky–Lutwak–Yang–Zhang as a spectral problem in centro-affine differential geometry. In particular, we show that the Hilbert–Brunn–Minkowski operator coincides with the centro-affine Laplacian, thus obtaining a new avenue for tackling the conjecture using insights from affine differential geometry. As every strongly convex hypersurface in

\mathbb{R}^n

is a centro-affine unit sphere, it has constant centro-affine Ricci curvature equal to

n-2

, in stark contrast to the standard weighted Ricci curvature of the associated metric-measure space, which will in general be negative. In particular, we may use the classical argument of Lichnerowicz and a centro-affine Bochner formula to give a new proof of the Brunn–Minkowski inequality. For origin-symmetric convex bodies enjoying fairly generous curvature pinching bounds (improving with dimension), we are able to show global uniqueness in the

L^p

- and log-Minkowski problems, as well as the corresponding global

L^p

- and log-Minkowski conjectured inequalities. As a consequence, we resolve the
isomorphic
version of the log-Minkowski problem: for any origin-symmetric convex body

\bar K

in

\mathbb{R}^n

, there exists an origin-symmetric convex body

K

with

\bar K \subset K \subset 8 \bar K

such that

K

satisfies the log-Minkowski conjectured inequality, and such that

K

is uniquely determined by its cone-volume measure

V_K

. If

\bar K

is not extremely far from a Euclidean ball to begin with, an analogous
isometric
result, where

8

is replaced by

1+\varepsilon

, is obtained as well.
On the Semi-absoluteness of Isomorphisms between the Pro-$p$ Arithmetic Fundamental Groups of Smooth Varieties
Authors: Tsujimura Shota
Published: October 2023

Let

p

be a prime number. In the present paper, we consider a certain pro-

p

analogue of the semi-absoluteness of isomorphisms between the étale fundamental groups of smooth varieties over

p

-adic local fields [i.e., finite extensions of the field of

p

-adic numbers

\mathbb{Q}_p

] obtained by Mochizuki. This research was motivated by Higashiyama’s recent work on the pro-

p

analogue of the semi-absolute version of the Grothendieck conjecture for configuration spaces [of dimension

\geq 2

] associated to hyperbolic curves over generalized sub-

p

-adic fields [i.e., subfields of finitely generated extensions of the completion of the maximal unramified extension of

\mathbb{Q}_p

].
Two-phase models for elastic membranes with soft inclusions
Authors: Santilli Mario , Schmidt Bernd
Published: October 2023

We derive an effective membrane theory in the thin film limit within a two-phase material model for a specimen consisting of an elastic matrix and soft inclusions or voids. These inclusions may lead to the formation of cracks within the elastic matrix and the corresponding limiting models are described by Griffith-type fracture energy functionals. We also provide simplified proofs of relaxation results for bulk materials.
The KLiP Mobile: A model of community engagement programme
Authors: Muna’aim Maimunah  Abdul , Mokhtar Azlina , Khairudin Muhammad Najmi , Jaafa Hafiz , Azzeri Amirah , Mohd Tengku Amatullah Madeehah Tengku
Published: October 2023

Background: KLiP Mobile (Klinik pakar bergerak) is a mobile eye specialist clinic initiated by the state government of Negeri Sembilan and Universiti Sains Islam Malaysia (USIM). It is funded by the state of Negeri Sembilan and managed by USIM.   
Objectives: The four objectives of this programme are: 1) Providing essential eye services, 2) Enhancing public-private partnerships to support the programme, especially among the underprivileged community for cataract surgery, rehabilitation of vision, and glasses for children and elderly 3) Promoting awareness through knowledge transfer programme on eye disease 4) conducting research. This paper aims to describe the prevalence of common eye diseases among our target population in Negeri Sembilan.   
Method: This is a cross-sectional study consisting of referred or walk-in patients who visited the KLiP Mobile program between January 2016 to June 2022.   
Results: The result showed the prevalence of common eye diseases among the population and is comparable with our national eye survey.   
Conclusion: The KLiP Mobile is a model of community engagement programme and is expected to continue benefiting the community especially those who are unable to access specialist services.
Drug cost analysis of outpatients with cardiovascular disease under the national health insurance scheme
Authors: Nur Andi Bulqiah , Suprapti Budi , Yulistiani Yulistiani , Yusuf M. , Kurniawati Nelly
Published: October 2023

Background: Cardiovascular disease is one of the catastrophic diseases that absorbs the most health budgets. Reimbursement of healthcare costs from the National Health Insurance Agency is done through the case-based groups (INA-CBGs) and fee-for-service (non-INA-CBGs) methods based on e-catalogue drug prices. Drug costs are a concern.    
Objective: To evaluate drug prescription compliance to the national formulary, total drug cost and drugs cost included in the INA-CBGs package.       
Method: This observational study used retrospective prescription data from the outpatient Cardiology Clinic. A quantitative analysis was conducted for prescription compliance with formulary and drug costs.   
Result: Out of the 4,443 prescriptions, the prescription alignment with the national formulary was  98%. The difference between the total e-catalogue and the actual drug costs was IDR4,818,252 (0.9%) (p > 0.05). Drug costs constitute 19%  of the INA-CBGs package.    
Conclusion: Drug prescribing is quite efficient with 98% compliance with the formulary and drug costs constitute 19% of the INA-CBGs package.
Intersectoral leadership on family planning programme performance: A prospective longitudinal study
Authors: Prasetyorini Anif , Muhadi  , Puryanti  , Rochmah Thinni Nurul , Suhariadi Fendy
Published: October 2023

Background: There had been no research on shared leadership at the team level in diverse organisation.    
Aims: This study aimed to investigate the effect of shared intersectoral leadership on family planning programme’s performance.    
Method: This was an observational study with a prospective longitudinal time series design. This study distributed questionnaires to 30 teams which were taken by simple random sampling to provide agreed answers. The measurement of the impact of shared leadership on performance was carried out three times. Linear regression was then used to analyse the data. The shared leadership team qualified as adequate.    
Result: The beta coefficient value indicated that shared leadership had a strong impact on the team’s performance of the family planning programme with a value of 0.817 - 0.824 (p = 0.000).
Conclusion: Once the shared leadership approach is effectively utilised, the team performance of family planning programmes will improve.
Food security and parenting as risk factors of stunting in toddlers aged 24 to 59 months
Authors: Rohmawati Ninna , Akbar Abdul Azis , Nurfaradila Tiara
Published: October 2023

Background: Stunting is one of the global health problems that need to be considered because the impacts are very complex and long term. There are various factors that influence the incidence of stunting, including food security and parenting.
Objective: The aim of this study was to analyse the status of household food security and parenting, as risk factors of stunting among toddlers in Pamekasan regency. 
Method: This research was done using the observational analytic with a case control design.
Result: Household food security status had a significant relationship with the incidence of stunting. Toddlers who were in food-insecure households had a 3.5 times greater risk of experiencing stunting compared to toddlers in food-resistant families. There is a relationship between these two variables. Toddlers with poor parenting had an 8.4 times higher risk of experiencing stunting compared to toddlers with good parenting. 
Conclusion: The status of household food security and parenting is a risk factor for the incidence of stunting.
Soursop leaf extract (Annona muricata L) as a biochemical pesticide against fruit flies (Bactrocera sp)
Authors: Ningrum Prehatin Trirahayu , Ekaningrum Yulis , Pujiati Rahayu Sri
Published: October 2023

Background: The citrus cultivation industry is commonly operated by the government, private sector, or individual owners from small, medium, to large scales. The fruit flies (Bactrocera sp) insect was reported to attack citrus crops in almost every region in Indonesia.    
Objective: To determine the effectiveness of soursop leaf extract (Annona muricata L) as a plant-derived insecticide against fruit flies.    
Methods: This study used true experimental with Posttest Only Control Design to analyse the difference in the average mortality of fruit flies for 24 hours.   
Results: The data generated through the Kruskal Wallis test showed that at a concentration of five per cent and 10% the effect of the mortality in fruit flies equals p > 0.939. However, at a concentration of 15%, the number decreased to p < 0.001. This finding showed that the compound has evolved its function to antifeedant only or as a secondary metabolite that does not result in immediate death but rather gives discomfort to insects.    
Conclusion: The use of an antifeedant compound as a biopesticide can inhibit fruit flies’ attack on citrus crops.
El material autoconstruido en Educación Física: fortalezas y virtudes
Authors: Cubillo León Rodrigo
Published: October 2023

La incorporación de modelos pedagógicos en el aula es una realidad cada vez más extendida. El presente trabajo busca exponer y justificar el gran potencial del modelo de autoconstrucción de materiales en la materia de Educación Física. La autoconstrucción de materiales, como modelo pedagógico emergente, surgió para dar solución a tres cuestiones. Por un lado, superar las limitaciones derivadas de los bajos presupuestos; por otro lado, posibilitar la adaptación de herramientas a las necesidades del aula y, por último, crear conciencia ambiental. Con este modelo se busca fomentar la motivación y creatividad del alumnado dando una segunda vida a materiales de desecho, consiguiendo con ello un amplio abanico de ejercicios y actividades con los que seguir aumentado el bagaje motor del alumnado a través de un proceso de enseñanza activo, social y creativo. Su empleo está justificado a nivel curricular, y permite la hibridación con otros modelos pedagógicos, además de facilitar el trabajo interdisciplinar con otras materias. Por todo esto, la autoconstrucción de materiales se presenta como un modelo óptimo para abordar la diversidad en el aula a través de actividades innovadoras y motivantes, escapando de la monotonía instaurada por la limitación de material existente en la materia de Educación Física. Con este modelo, el docente, desde el conocimiento y control de su grupo clase, puede estimular el proceso de enseñanza-aprendizaje sacando el máximo potencial de cada alumno.
FEATURES OF THE FORENSIC METHODOLOGY FOR INVESTIGATING CRIMINAL ATTACKS AGAINST THE PERSON COMMITTED USING INFORMATION AND TELECOMMUNICATION NETWORKS
Authors: Vostrikov Gleb A.
Published: October 2023

The development of information and telecommunication networks, in addition to the ease with which data are transmitted, provides criminals with an effective tool that can enhance the guarantees of achieving their goals. In addition to increasing the social danger of the crimes in which this tool is used, another effect is achieved, which is to make it difficult to investigate. This creates problems in establishing the truth. The purpose of the study is to determine the type of forensic methodology, the application of which is able to optimize the investigation of each specific criminal assault on a person committed using information and telecommunication networks. Materials and Methods. The objective was achieved through the application of methods such as analysis, synthesis, deduction, induction, modelling (general science), as well as systems and forensic sitology (forensic). Results. The study identified problems that arise in the practice of investigating criminal attacks against persons committed using information and telecommunication networks. Funding was analyzed for their resolution. It has been established that the forensic methodology for its effectiveness should be based on typical knowledge of the use of information and telecommunication networks in these crimes. This should be a comprehensive investigative technique. Conclusions. Comprehensive methods of investigation of criminal attacks against the person committed with the use of information. The telecommunications network makes it possible at an early stage to avoid errors and to ensure that the circumstances most relevant to a fair trial are established.
Spironolactone Does Not Prevent Restenosis After Coronary Stenting in Humans
Authors: Kursaklioglu H , Iyisoy A , Amasyali B , Celik T , Ozturk C , Kose S , Isik E
Published: October 2023

Introduction: In animal studies, aldosterone enhanced neointimal proliferation by increasing extracellular accumulation of collagen and potentiating the effects of angiotensin II. Spironolactone, an aldosterone antagonist, is a potent inhibitor of neointimal proliferation. We conducted a placebo-controlled, double-blind, randomised study to assess the effect of spironolactone on angiographic 6-month in-stent restenosis.

Materials and Methods: Of the 310 randomised patients with significant coronary artery disease, 258 patients were available for analysis: 128 constituted the placebo group and 130 were assigned to receive spironolactone. Eligible patients were randomly assigned to receive a dose of 50 mg spironolactone or placebo orally twice a day for 6 months. The primary endpoint was the angiographic restenosis (>50% stenosis) rate at follow-up angiography.

Results: At 6-month follow-up angiography after stenting, there was no difference between the 2 groups in minimal lumen diameter, percent diameter stenosis, late loss, and net gain. Angiographic restenosis occurred in 46 (35.4%) of 130 patients receiving spironolactone and 50 (39.0%) of 128 in the placebo group with an odds ratio (OR) of 0.85 with a 95% confidence interval (CI) of 0.49 to 1.46 (P = 0.62). Restenosis rate was found in 60 (32.9%) of 182 lesions in the spironolactone group, and 61 (35.5%) of 172 lesions in the placebo group with an OR of 0.89 with a 95% CI of 0.56 to 1.42 (P = 0.89).

Conclusions: Spironolactone did not reduce the incidence of in-stent restenosis as compared with placebo in human, contrary to the fact that reduction of neointimal formation in animal models has been observed upon administration of spironolactone.
Standards and Revalidation or Recertification
Authors: Irvine D
Published: October 2023

Patients want doctors who are competent, respectful, honest and able to communicate with them. This is patient-centred professionalism. In the United Kingdom, it is being embedded into practice by the General Medical Council (GMC) through medical regulation in a partnership between the public and doctors. The foundation is a national code of professional standards – Good Medical Practice – that has been tied to medical licensure to secure doctors’ continuing compliance whilst they are in active practice. The revalidation of a doctor’s license to practise is the means of achieving such compliance. Revalidation requires that specialists and general practitioners must be able to demonstrate – on a regular basis – that they are keeping themselves up to date and remain fit to practise in their chosen field. It begins in April 2005. For revalidation, doctors’ performance, conduct and health will be assessed against the headings of Good Medical Practice. Doctors will collect a folder of illustrative evidence that will form the basis of an annual appraisal carried out at the workplace by an appropriately trained colleague. The results of these annual appraisals will be submitted to the GMC for a revalidation decision every 5 years. Where doctors’ performance or conduct gives cause for concern, they may have to undergo a further searching assessment under the GMC’s Fitness to Practise Procedures. Under these procedures the GMC can order a doctor to retrain or, if circumstances warrant it, to stop practising.
15th Chapter of Surgeons Lecture: Surgeon of the New Millennium – Surgeon, Scientist and Scholar
Authors: Tan SK
Published: October 2023

The surgeon of the new millennium has come a long way from his humble beginnings in the Middle Ages as the lowly barber-surgeon. The skills and techniques developed by outstanding surgeons like Astley Cooper of the 19th century have withstood the test of time and have been refined by subsequent generations of surgical masters. The scientific basis of modern surgery was put on a firm footing in the early 19th century through the discovery of anaesthesia and microorganisms as a cause of many diseases and surgical complications. The 20th century brought about rapid progress in medicine, information technology (IT) and the life sciences, and closed with a big bang with the completion of the sequencing of the human genome. For the surgeon of the 21st century to remain relevant, he must embrace the concept of the Total Surgeon. Not doing so will render him irrelevant in the course of time, for having good surgical technique alone is insufficient. He must also lead in scientific endeavours to push the frontiers of the life sciences in attempts to solve the insoluble, and be scholarly in thought, attitude and behaviour. In other words, he must be a Surgeon-Scientist-Scholar.
Axoglial Interaction via the Notch Receptor in Oligodendrocyte Differentiation
Authors: Hu QD , Cui XY , Ng YK , Xiao ZC
Published: October 2023

Introduction: Increasing evidence has revealed that the Notch signalling pathway is one of the pivotal systems that mediate oligodendrocyte development. The Notch receptor is a type I transmembrane molecule that represents a novel cellular signalling paradigm, namely, regulated intramembrane proteolysis (RIP).

Method: The typical Notch ligands, such as Delta, Serrate/ Jagged and Lag2 (DSL), promote the formation of oligodendocyte precursor cells (OPCs) and maintain them in an uncommitted stage, thus retarding oligodendrocyte appearance in the central nervous system (CNS).

Results: In contrast, our recent studies have revealed that F3/ contactin, a GPI-linked neural adhesion molecule, interacts with Notch and speeds up the generation and maturation of oligodendrocytes.

Conclusions: Considering the distinct, albeit somewhat overlapping expression patterns of F3 and DSL in the CNS, the Notch receptor appears to function ligand-dependently during oligodendrocyte development. This multipotentiality may well designate the Notch receptor as one of the therapeutic targets that one can manoeuvre to treat demyelinating diseases, such as multiple sclerosis, that is characterised by chronic myelin degeneration.
Merging Medicine with Science: The Birth of a Targeted Therapy in Cancer
Authors: Mendelsohn J
Published: October 2023

We will review the development of a new anticancer therapy which acts by blocking the EGF receptor (EGFR) protein on the surface of cancer cells. The research began in 1981 and has not ended. Participants have included scientists in universities, biotech and pharmaceutical companies, the US National Cancer Institute, the Food and Drug Administration (FDA), clinical investigators at many cancer centres, and thousands of patients.
UMA REVISÃO DA LITERATURA BRASILEIRA SOBRE OS MODELOS DE GERENCIAMENTO MATRICIAL DE DESPESAS
Authors: De Souza Ermerson Rogério , Pinto Anderson Rogério Faia , Pacheco Bruna Cristine Scarduelli , Bonizio Roni Cleber
Published: October 2023

A melhoria da capacidade competitividade de uma empresa requer uma gestão eficaz dos gastos. Uma ferramenta que propicia uma visão detalhada e estratégica dos gastos é o Gerenciamento Matricial de Despesas (GMD). Entretanto, não há produções científicas com foco em revisões de literatura sobre o GMD. Logo, este artigo tem como objetivo apresentar uma revisão da literatura brasileira sobre os estudos publicados acerca do GMD. É o primeiro artigo a fornecer uma análise sobre abordagens do GMD publicadas nas bases científicas do Brasil. A metodologia de pesquisa empregou uma revisão de literatura de natureza exploratória e descritiva em torno do GMD. As buscas nas bases de dados científicas se estenderam até junho de 2022. As análises dos resultados demostraram que o GMD é mais aplicado nos segmentos de Saúde (25%), Alimentícia (15%), Metalúrgica (10%) e Órgãos Públicos (10%). A principal contribuição deste artigo está em fornecer um arcabouço teórico que corrobora com os avanços na aplicação do GMD no Brasil. Assim sendo, este artigo pode apoiar gestores, estudantes e pesquisadores sobre os processos de implantação e implementação do GMD. Uma importante sugestão para futuros estudos é melhor adaptar o GMD às empresas de vários segmentos no Brasil.
CUSTOS OCULTOS EM UMA PEQUENA EMPRESA: ESTUDO DE CASO ÚNICO EM UM SUPERMERCADO EM RECIFE, PERNAMBUCO
Authors: Dominguez Arita Indira Scarlett , Cunha Callado Antônio André
Published: October 2023

O presente artigo tem como objetivo identificar os custos ocultos em um supermercado localizado na cidade de Recife, Pernambuco. Trata-se de uma pesquisa descritiva com abordagem qualitativa aplicada a um estudo de caso único. Durante o processo de pesquisa foram utilizados instrumentos de coleta de dados, como a entrevista semiestruturada e a observação direta. A microempresa está localizada no bairro da Várzea e possui uma estrutura organizacional composta por diversos departamentos, como: departamentos básicos, atendimento ao cliente, contabilidade, recursos humanos e gestão até as áreas mais específicas de um supermercado, como de vendedores e a de reabastecimento. Ao longo da pesquisa se percebeu a necessidade de realizar um mapeamento efetivo de todo o processo operacional. Sendo que esse mapeamento deve ser orientado para os custos, permitindo a identificação efetiva dos custos ocultos. Dentro da microempresa, uma das principais causas que geram custos ocultos é o estoque interno que o supermercado possui, por isso vê-se a necessidade de criação e implementação de ferramentas que permitam um melhor controle do sistema de abastecimento.
Identification of staphylococcal enterotoxin b in dairy products by immunochromatography with visual and digital video detection
Authors: Yarkov SP , Tretyakov SI , Shilenko IV , Ishkov YuN , Styazhkin KK
Published: October 2023

Detection of staphylococcal enterotoxins in food products is an important task of food poisoning prevention. The study was aimed to develop immunochromatography tests (ICTs) for detection of staphylococcal enterotoxins А (SEA) and be В (SEB), as well as to improve sensitivity of immunochromatography detection of staphylococcal enterotoxins (by the example of SEB) in dairy products relative to visual assessment by recording the analysis results with digital video recorders (DVR) using the principle of processing digital immunochromatogram images acquired using illumination in various spectral ranges. ICTs for detection of enterotoxins were designed as sandwich tests based on highly specific monoclonal antibodies (MABs) against staphylococcal enterotoxins. Milk, cream, sour cream, cheese artificially contaminated with SEB were analyzed. The analysis results were recorded visually or by DVR. DVR of immunochromatograms of the enterotoxin-containing dairy products acquired using illumination with white light in the wavelength range of 400–800 nm ensures a 4-fold increase in the SEB detection sensitivity, while that involving illumination with green light in the wavelength range having its maximum at 525 nm ensures a 4–8-fold increase relative to visual recording. The use of the “Reflecom” and “Zondazh” digital video immunochromatogram analyzers multiplies sensitivity of SEB detection by immunochromatography when assessing dairy products relative to visual recording.
Heart disease in young elite athletes having a history of COVID-19
Authors: Makarov LM , Komolyatova VN , Kiselyova II , Besportochny DA , Akopyan AG , Dmitrieva AV , Aksenova NV
Published: October 2023

The impact of coronavirus infection (SARS-CoV-2) on cardiac output in underage athletes is uncertain. The study was aimed to determine heart disease in young elite athletes having a history of COVID-19 (SARS-CoV-2). A retrospective analysis of the results of the developed three-phase medical assessment of 236 elite athletes aged 14–17 (16 ± 1), who had had SARS-CoV-2 infection, was performed. The first phase of assessment involved examination, ECG, ECHO, bicycle ergometry (BEM), creatine kinase and creatine kinase MB tests. During the second phase 22 athletes (9.3%) underwent a more thorough assessment that included Holter monitoring (HM) with heart rate turbulence (HRT), microvolt T–wave alternans (MTWA), heart rate variability (HRV) estimation, high-resolution ECG (HRECG), determination of myocardial damage biochemical markers (troponin, NТproBNP) due to alterations revealed. Seven athletes (32%) having alterations revealed during this phase were referred to gadolinium enhancement cardiac magnetic resonance imaging (MRI) (the third phase). Myopericarditis was diagnosed in four cases (1.7% of 236) based on the results. Thus, low (below 2%) myocardial involvement has been revealed in young elite athletes, who have a history of SARSCoV-2 infection. Cardiovascular assessment algorithm has been developed for such athletes. Detection of cardiac arrhythmias by ECG, BEM, and HM is the most informative. HRECG, HRV, HRT, and MTWA can be used as additional methods to determine indications for MRI as a gold standard of the diagnosis of myocarditis.
Pelaksanaan Gadai Tanah Menurut Masyarakat Adat Madura
Authors: Khomaizah Khomaizah , Tjoanda Merry , Matuankotta Jenny Kristiana
Published: October 2023

Introduction: Agricultural land mortgage is the act of transferring land rights to another person which is done clearly and in cash, the party who transfer the title has the right to redeem the land. Than the transfer of land rights to the pawn is temporary. Facts in the field pawn land is done in a customary way, wich causes the mortgage time to last for years. This contradicts which law No. 5 of 1960 agrarian basic regulations and 7 paragraph 1 of law No. 56 of 1960 the determination of agricultural area. 

Purposes of the Research: This study aims to analyze the implementation of land pawning in the madurese indigenous people.

Methods of the Research: The research approach method used is a statutory approach and a conceptual approach. The bahan hukum obtained in the form of primary bahan hukum and secondary bahan hukum and tertiary bahan hukum. This type of research is normative research through literature study. Bahan hukum were analyzed by qualitative analysis by presenting bahan hukum in narrative form.

Results Originality of the Research: The results of the study show that the practice of pawning agricultural land in the madurese community continues for years, even to the customary heirs there. And do not follow according to the provisions 7 paragraph 1 of law No. 56 of 1960 the determination of agricultural area. This requires legal protection against the implementation of land pledges that are nt in accordance with artcle 7 of law No. 56 of 1960. The land mortgages that exceed 7 year must be returned to the owner without ransom. As well as legal consequences for the implementation of land pawning without a time limit that occurred in Waru Pamekasan Madura, that can be subject to a 3-mont sanction and or a maximum fine of 10.000.
Efektivitas Penegakan Hukum bagi Pelaku Pertambangan Emas tanpa Izin (Illegal Mining)
Authors: Sulaiman Banta
Published: October 2023

Introduction: Illegal Mining is Illegal Mining that is carried out without a permit so that it violates the law.  Carrying out illegal mining is the same as committing a crime against State Assets, the purpose of Illegal Mining is Extraction of Natural Resources by the community or company without following operational procedures and government regulations. 

Purposes of the Research: The aim of the research is to examine the effectiveness of law enforcement against the crime of gold mining without a permit and to find out the obstacles in law enforcement.  

Methods of the Research: this research was conducted using the Juridical Empirical research method, the data used is the result of facts from the field by interviewing the Nagan Raya Police, Judges of the Suka Makmue Court and Nagan Raya Legal Academics.

Results Originality of the Research: The results of the research show that law enforcement against gold miners without permits is not effective.  This is evidenced by cases that always exist every year even though law enforcement has been carried out by law enforcement.  The obstacle in handling this case was that when an investigation was carried out, the perpetrator had already received information.
Penolakan Pasien Dalam Keadaan Darurat Karena Belum Divaksin
Authors: Sangadji Nandito Joi , Wadjo Hadibah Zachra , Tuhumury Carolina
Published: October 2023

Introduction: Criminal liability arises when the damage caused by the negligence of the hospital's medical staff meets three factors: The three factors are the presence or absence of negligence, wrongdoing, and other relevant sanctions. In addition, under the criminal justice system, if a company commits a crime, its owner can be jailed or fined.Purposes of the Research: This study aims to analyze and explain the refusal of patients in an emergency situation because they have not been vaccinated against the Health Law Number 36 of 2009 and to analyze and explain the legal policy mechanism taken for patients in an emergency situation because they have not been vaccinated who are referred to the hospital.Methods of the Research: The type of research used is normative, which is focused on providing explanations that explain a particular category. Approach the problem of the statute approach (statute approach) and the conceptual approach (conceptual approach). The collection of legal materials through primary legal materials is then free from secondary legal materials. The processing and analysis of legal materials is described in a qualitative way with the aim of describing the findings in the field.Results of the Research: The refusal of patients in an emergency situation because they have not been vaccinated is contrary to the Health Law No. 36 of 2009. In which the Law of the Republic of Indonesia No. 36 of 2009 concerning Health has regulated the refusal of health services by hospitals. The legal policy mechanism that is taken for emergency patients because they have not been vaccinated is that they still pay attention to the existing legal rules for both patients and for the hospital, by prioritizing patient safety first, all patients are entitled to outpatient medical services, inpatient care, or emergency department at a health facility. This is regulated in the Law of the Republic of Indonesia number 29 of 2004 concerning medical practice, Law of the Republic of Indonesia number 36 of 2009 concerning health. The refusal to take care of the patient's health is ignored by medical institutions, because it can worsen the patient's condition.
Biodegradação de fezes de cães pela digestão anaeróbia em diferentes faixas de temperatura
Authors:   , Fiães Gabriela Maria Fernandes
Published: October 2023

As fezes caninas são geradas em elevadas quantidades, em especial pelo aumento do número de animais em canis. A digestão anaeróbia das fezes caninas pode ser uma alternativa interessante para o seu tratamento, com potencialidades de recuperação do biogás e uso do digestato como biofertilizante. O objetivo deste trabalho foi avaliar a biodegradação de fezes de cães pela digestão anaeróbia em diferentes condições de temperatura e relação inóculo/substrato. O estudo compreendeu o monitoramento da geração de fezes caninas em um canil no município de Viçosa (Minas Gerais-Brasil). A quantificação e a caracterização físico-química/microbiológica dos resíduos foram realizadas por um período de 1 mês. Testes de biodegradabilidade (PBM) foram conduzidos para se avaliar os efeitos da relação inóculo:substrato (I:S) de 1:2, 1:1 e 2:1, assim como a influência da temperatura na degradação dos resíduos: (i) ambiente (17°C a 22°C), (ii) mesofílica (35°C), termofílica (55°C), e mista (55°C + 35°C). Estudos cinéticos foram realizados para os modelos de 1° ordem, Gompertz modificado e Cone. Estimou-se o potencial energético do biogás para o canil monitorado. A qualidade do digestato foi avaliada em termos de lançamento em corpos hídricos e atendimento a diretrizes para fertirrigação. A relação I:S que gerou o maior volume de biogás foi a de 1:1 (298,6 mL.g−1SV), sendo utilizada esta relação na segunda etapa dos estudos de biodegradabilidade. O tratamento mesofílico (316,9 mL.g−1SV) gerou um volume de biogás consideravelmente maior que o tratamento termofílico (202,7 mL.g−1SV). Os teores médios de metano produzidos foram semelhantes para os tratamentos mesofílico (48,9%) e termofílico (48,3%). O modelo cinético mais adequado de forma geral para todos os tratamentos foi o Gompertz modificado. Além disso, a produção de energia encontrada para os tratamentos ambiente, mesofílico e termofílico foi de 23,27 MJ.d−1, 39,24 MJ.d−1 , e 25,00 MJ.d−1, respectivamente. A geração de fezes caninas foi de 240 g.animal-1.d-1. A digestão anaeróbia se mostrou vantajosa para o tratamento de fezes caninas em termos de recuperação de recursos e gerenciamento deste resíduo. Palavras-chave: Mesofílica. Termofílica. Fertirrigação.
Códigos de grupo, LCD e auto-ortogonais construídos a partir de p-grupos abelianos finitos
Authors:   , Souza Pedro Leonardo Pinto de
Published: October 2023

Neste trabalho descrevemos os idempotentes primitivos da álgebra de grupo Fq G = Fq (Cpm × Cpn ), em que Cpm e Cpn são, respectivamente, grupos cíclicos de ordem pm e pn . Para tanto, elaboramos alguns exemplos nos quais calculamos os elementos idempotentes a partir da teoria de corpos ﬁnitos. Além disso, calculamos os idempotentes, por meio de exemplos, a partir da teoria de grupos. Nosso objetivo é mostrar, na prática, como devemos transitar seguramente entre essas diferentes abordagens, evidenciando as relações entre elas e as consequências nos cálculos dos idempotentes, gerados pela diferença das hipóteses adotadas em cada caso. Por ﬁm, descrevemos todos os códigos abelianos LCD e auto-ortogonais da álgebra de grupo Fq G a partir dos idempotentes primitivos previamente calculados. Palavras-chave: Códigos. Idempotentes. Primitivos.
From a dermatologist point of view, enthesopathy and peripheral neuropathy in psoriasis patients
Authors: KULAKLI Sevgi , ATAKAN Nilgün , ÇAĞLAYAN Gökhan , AKINCI Ayşen , ÖZÇAKAR Levent
Published: October 2023

Background: Investigating psoriasis patients’ enthesopathy and peripheral neuropathy, which dermatologists often neglect.Methods: Seventy-four psoriasis patients’ lower limb entheses were evaluated by ultrasonography using Glasgow Ultrasound Enthesitis Scoring Scale (GUESS). Sensory and motor nerve conduction studies in median and ulnar nerve, motor nerve conduction research of peroneal and tibial nerves and sensory conduction study on right sural nerve was performed in 25 patients.Results: 172 of 730 entheses had ultrasonographic enthesopathy symptoms (23.56%). Enthesopathy was substantially more common in cases involving the nail (p = 0.004). The frequency of enthesopathy did not change significantly between symptomatic and asymptomatic patients (p = 0.408). Seven of 25 patients (28%) had a pathology in nerve conduction studies. With increasing GUESS scores, bilateral ulnar and right tibial nerve distal motor latencies were shown to become longer (p = 0.001, p = 0.01, p =0.019), although left ulnar nerve sensory conduction velocity got slower (p = 0.033).Conclusions: Enthesopathy and peripheral nerve dysfunction were frequently observed in psoriasis patients. Dermatologists should be mindful of neuromusculoskeletal disorders in psoriasis patients.
What is the ideal repair technique for triple hernia accompanied by umbilical and bilateral inguinal hernias?
Authors: TÜRKAN Ahmet , ERDOĞAN Ahmet
Published: October 2023

Background: For patients with bilateral inguinal hernia (BIH) accompanied by an umbilical hernia (UH), there may be hesitations regarding the repair of all three hernias in the same session in terms of pain and possible problems in the healing process. Studies on these patients are rather rare in the literature. In the present study, the results of laparoscopic and open surgical treatment in patients with triple hernia accompanied by BIH and UH were compared.Methods: The data of patients were analyzed retrospectively. Patients whose hernias were fully repaired with open surgery made up group 1, and patients who underwent laparoscopic transabdominal preperitoneal (TAPP) repair together with open UH repair made up group 2. There were 10 patients in group 1 and 11 patients in group 2. The patients’ umbilical defect diameter, whether inguinal hernia (IH) was scrotal or not, applied surgical technique, length of hospital stay, duration of the operation, postoperative complications, and recurrence status were evaluated. Results: While 19 (90.5%) of the patients were male, 2 (9.5%) were female. In group 2, recurrence of unilateral IH was seen in 1 (4.5%) patient. Complications developed in 3 (14.3%) patients: seroma in 1 patient in group 1; and seroma in 1 patient; and wound infection in another patient in group 2. There was no significant difference between the groups in terms of duration of the operation, length of hospital stay, or postoperative complications (p value, p=0.251, p=0.756, p=0.538, respectively)Conclusion: In patients with triple hernia where umbilical and BIH occur together, open UH repair and IH repair can be performed safely by TAPP repair.
Chronic Kidney Disease Observational Cohort Study And Assessment Of Baseline Characteristics And Their Relationship With Diabetes Status And Kidney Function
Authors: KOYUNCU Sümeyra , ULUDAG Koray , GÜNAL Ali İhsan
Published: October 2023

Background: Chronic kidney disease (CKD) may result in end-stage renal disease (ESRD), and undesirable outcomes such as death and dialysis. We carried out an observational cohort study to ascertain risk factors for the renal outcomes, all-cause mortality in patients with CKD. In this report, we studied the baseline demographic and laboratory characteristics of the cohort.
Methods: A single-center, retrospective, observational cohort study was conducted at the outpatient Nephrology Clinic of Health Sciences University, Kayseri Medical Faculty, from January 1, 2010, to December 31, 2020. Age 18 to 70 years and eGFR 15 to 59 mL/min/1.73 m2 were inclusion criteria. Baseline demographic and laboratory data were documented.
Results: One thousand seventy-three patients with CKD were enrolled in the study. Mean (SD) age was 55.87 (8.83) years, and 53.2% were men. %45.9 and %84.4 had diabetes mellitus and hypertension, respectively. The mean body mass index was 26.73 (3.95) kg/m2. Mean eGFR was 34.14 (10.45) mL/min/1.73 m2 using chronic kidney disease epidemiology collaboration. Median (p25-p75) urinary protein-creatinine ratio was 48.80 [22.40, 89.00] mg/mmol. Older patients had a lower eGFR, and the male gender was more common at stage 3 patients. Stage 4 patients had lower hemoglobin and serum calcium levels. Also, low eGFR was associated with high uric acid levels.
Conclusion: This study along with future analysis may elucidate the natural history and clinical consequences of CKD. Controllable factors could be understood, and CKD progression and adverse outcomes may be prevented in this way.
Fibrin Membrane Induced Pupillary Block Glaucoma Treated With Nd:YAG Laser After Uncomplicated Cataract Surgery
Authors: SÜMER Fatma
Published: October 2023

Background: Fibrin pupillary-block glaucoma is a rare complication after uneventful cataract surgery. We aimed to share our treatment approach with Nd: YAG laser fibrin membranotomy.

Case presentation: A 68-year-old male patient without any systemic comorbidity developed acute intraocular pressure elevation with a shallow anterior chamber 7 days after uneventful cataract surgery. Visual acuity (VA) of the right eye was 0.1 and IOP was 48 mmHg. There was a fibrin membrane that completely closed the pupillary space. It was observed that there was 360-degree iridocorneal contact in the periphery. An Nd: YAG laser was applied to create an opening at the upper edge of the fibrin membrane. A rapid deepening of the anterior chamber was observed immediately after perforation of the membrane. After deepening of the anterior chamber, permanent peripheral iridotomy was opened with argon-Nd: YAG.

Conclusion: Although the fibrin membrane is seen after uneventful cataract surgeries usually suggests which inflammation is triggered, these results can sometimes occur even before the disease is present.
Determining the turnaround time in a newly established biochemistry laboratory
Authors: ÖZTÜRK Alpaslan , DEMİRCİ Gülşah
Published: October 2023

Background: The aim of our study was to compare the request-to-result times in the central biochemistry laboratory of Etlik City Hospital temporally and between clinics and to reveal the reasons for the changes in these times.

Methods: The time of acceptance of the samples to the Central Biochemistry Laboratory of Etlik City Hospital and the time of confirmation of the results were noted and the difference between these two times was taken.

Results: Delay rates were significantly different between the inpatients in October, November and December (P
Primary epiploic appendagitis: A retrospective analysis of clinical and tomographic findings in 14 patients
Authors: ÇEVİK Belma , KASAPOĞLU Benan
Published: October 2023

Background: The aim of this study is to describe the clinical features and imaging findings of 14 patients diagnosed with primary epiploic appendagitis on computed tomography (CT).
Methods: Between January 2019 and August 2022, the hospital records of 14 patients were retrospectively reviewed. We recorded patients' age, gender, fever presence, blood leukocyte count (WBC), C-reactive Protein (CRP) level, localization of abdominal pain, the presence of nausea or vomiting, the involved part of the colon on CT, whether they received treatment or not, and whether they underwent surgery.
Results: This study included 14 patients, 8 male and 6 female. Their ages ranged from 27 to 63 years. All patients presented with acute abdominal pain in most cases, with no elevation in body temperature or significant increase in inflammation markers. CT scan images showed a fat oval lesion corresponding to the inflamed Appendix epiploica, with a peripheral hyper-attenuated frame and a central "dot" in some cases referring to the thrombosed vessel. The patients were successfully treated with conservative methods.
Conclusions: Epiploic appendagitis can mimic surgical diseases such as appendicitis and diverticulitis due to its non-specific clinical presentation. CT scan is essential in diagnosing this disease, which can be managed with more conservative treatment methods.