bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of MCFA and Other Methods of Terminating Alcohol Fermentation and Their Influence on the Content of Carbonyl Compounds in Wine
Authors: Licek Josef , Baron Mojmir , Sochor Jiri
Published: December 2020

This study deals with the effects of the use of a mixture of medium-chain fatty acids (MCFA) at the end of the alcohol fermentation process on the content of carbonyl compounds in wine. During the experiment, the effects of the addition of MCFA at doses of 10 and 20 mg/L were compared to the termination of alcohol fermentation using cross-flow filtration and chilling treatments. Individual carbonyl compounds were determined by HPLC analysis. The experiment showed that the addition of MCFA caused a reduction of the acetaldehyde content compared to the chilling process, and a reduction of the diacetyl content compared to cross-flow filtration. Throughout the experiment, a lower level of total carbonyl compounds was observed after the addition of MCFA.
Determination and Comparison of Short-Chain Fatty Acids in Serum and Colon Content Samples: Alzheimer’s Disease Rat as a Case Study
Authors: Guo Lin-Xiu , Tong Yue , Wang Jue , Yin Guo , Huang Hou-Shuang , Zeng Long , Wang Ping , Li Jun-Peng , Bi Kai-Shun , Wang Tie-Jie
Published: December 2020

Short-chain fatty acids (SCFAs) are the main microbial fermentation products from dietary fibers in the colon, and it has been speculated that they play a key role in keeping healthy in the whole-body. However, differences in SCFAs concentration in the serum and colon samples had attracted little attention. In this study, we have optimized the extract and analysis methods for the determination of ten SCFAs in both serum and colon content samples. Methanol and acetonitrile were chosen for extraction of SCFAs from serum and colon content samples, respectively. Biological samples were collected from Alzheimer’s disease rats treated by extract of Schisandra chinensis (Turcz.) Baill (SC-extract) were taken as research objects. The results showed that, the relative peak intensities of SCFAs in the colon content from all groups were quite similar, and the trend was identical in the serum samples. Compared with the values in humans, the ratio of ten SCFAs in rat’s colon was similar, while the percent of acetate in rat’s serum was significantly higher. For therapy of Alzheimer’s disease (AD), SC-extract decreased the concentration of butyrate, 3-Methyvalerate, and caproate in the serum samples towards the trend of normal rats. This study may help our understanding of how SCFAs are transported across colonic epithelium in healthy and diseased organisms.
Kinetic Investigation on Tetrakis(4-Sulfonatophenyl)Porphyrin J-Aggregates Formation Catalyzed by Cationic Metallo-Porphyrins
Authors: Occhiuto Ilaria Giuseppina , Zagami Roberto , Trapani Mariachiara , Castriciano Maria Angela , Romeo Andrea , Scolaro Luigi Monsù
Published: December 2020

Under mild acidic conditions, various metal derivatives of tetrakis(4-N-methylpyridinium)porphyrin (gold(III), AuT4; cobalt(III), CoT4; manganese(III), MnT4 and zinc(II), ZnT4) catalytically promote the supramolecular assembling process of the diacid 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrin (H2TPPS4) into J-aggregates. The aggregation kinetics have been treated according to a well-established model that involves the initial formation of a critical nucleus containing m porphyrin units, followed by autocatalytic growth, in which the rate evolves as a power of time. An analysis of the extinction time traces allows to obtain the rate constants for the auto-catalyzed pathway, kc, and the number of porphyrins involved in the initial seeding. The aggregation kinetics have been investigated at fixed H2TPPS4 concentration as a function of the added metal derivatives MT4. The derived rate constants, kc, obey a rate law that is first order in [MT4] and depend on the specific nature of the catalyst in the order AuT4 > CoT4 > MnT4 > ZnT4. Both resonance light scattering (RLS) intensity and extinction in the aggregated samples increase on increasing [MT4]. With the exception of AuT4, the final aggregated samples obtained at the highest catalyst concentration exhibit a negative Cotton effect in the J-band region, evidencing the occurrence of spontaneous symmetry breaking. The role of the nature of the metal derivative in terms of overall charge and presence of axial groups will be discussed.
Alginic Acid from Padina boryana Abate Particulate Matter-Induced Inflammatory Responses in Keratinocytes and Dermal Fibroblasts
Authors: Jayawardena Thilina U. , Sanjeewa K. K. Asanka , Wang Lei , Kim Won-Suk , Lee Tae-Ki , Kim Yong-Tae , Jeon You-Jin
Published: December 2020

Particulate matter (PM) is a significant participant in air pollution and is hence an inducer of serious health issues. This study aimed to evaluate the dust protective effects of alginate from Padina boryana (PBA) via inflammatory-associated pathways to develop anti-fine dust skincare products. In between the external and internal environments, the skin is considered to be more than a physical barrier. It was observed that PM stimulates inflammation in the skin via activating NF-κB and MAPK pathways. The potential of PBA to inhibit the studied pathways were evident. The metal ion content of PM was considerably reduced by PBA and thus attributed to its chelation ability. Current research demonstrated the potential of P. boryana alginates to be implemented as a protective barrier against inflammation imposed with heavy metal and bacterial-derived endotoxin bound to the surface of the PM. Concisely, the results suggest that the bioactive components derived from the brown algae Padina boryana increased the cellular resistance to PM-stimulated inflammation-driven skin damage.
Physical, Thermal and Biological Properties of Yellow Dyes with Two Azodiphenylether Groups of Anthracene
Authors: Carabet Carla Alice , Moanță Anca , Pălărie Ion , Iacobescu Gabriela , Rotaru Andrei , Leulescu Marian , Popescu Mariana , Rotaru Petre
Published: December 2020

Two yellow bis-azo dyes containing anthracene and two azodiphenylether groups (BPA and BTA) were prepared, and an extensive investigation of their physical, thermal and biological properties was carried out. The chemical structure was confirmed by the FTIR spectra, while from the UV–Vis spectra, the quantum efficiency of the laser fluorescence at the 476.5 nm was determined to be 0.33 (BPA) and 0.50 (BTA). The possible transitions between the energy levels of the electrons of the chemical elements were established, identifying the energies and the electronic configurations of the levels of transition. Both crystals are anisotropic, the optical phenomenon of double refraction of polarized light (birefringence) taking place. Images of maximum illumination and extinction were recorded when the crystals of the bis-azo compounds rotated by 90° each, which confirms their birefringence. A morphologic study of the thin films deposited onto glass surfaces was performed, proving the good adhesion of both dyes. By thermal analysis and calorimetry, the melting temperatures were determined (~224–225 °C for both of them), as well as their decomposition pathways and thermal effects (enthalpy variations during undergoing processes); thus, good thermal stability was exhibited. The interaction of the two compounds with collagen in the suede was studied, as well as their antioxidant activity, advocating for good chemical stability and potential to be safely used as coloring agents in the food industry.
Developing a Library of Mannose-Based Mono- and Disaccharides: A General Chemoenzymatic Approach to Monohydroxylated Building Blocks
Authors: Tanzi Lisa , Robescu Marina Simona , Marzatico Sara , Recca Teresa , Zhang Yongmin , Terreni Marco , Bavaro Teodora
Published: December 2020

Regioselective deprotection of acetylated mannose-based mono- and disaccharides differently functionalized in anomeric position was achieved by enzymatic hydrolysis. Candida rugosa lipase (CRL) and Bacillus pumilus acetyl xylan esterase (AXE) were immobilized on octyl-Sepharose and glyoxyl-agarose, respectively. The regioselectivity of the biocatalysts was affected by the sugar structure and functionalization in anomeric position. Generally, CRL was able to catalyze regioselective deprotection of acetylated monosaccharides in C6 position. When acetylated disaccharides were used as substrates, AXE exhibited a marked preference for the C2, or C6 position when C2 was involved in the glycosidic bond. By selecting the best enzyme for each substrate in terms of activity and regioselectivity, we prepared a small library of differently monohydroxylated building blocks that could be used as intermediates for the synthesis of mannosylated glycoconjugate vaccines targeting mannose receptors of antigen presenting cells.
The Ketamine Antidepressant Story: New Insights
Authors: Alshammari Tahani K.
Published: December 2020

Ketamine is a versatile agent primarily utilized as a dissociative anesthetic, which acts by blocking the excitatory receptor N-methyl-d-aspartate receptor (NMDA). It functions to inhibit the current of both Na+ and K+ voltage-gated channels, thus preventing serotonin and dopamine reuptake. Studies have indicated that administering a single subanesthetic dose of ketamine relieves depression rapidly and that the effect is sustained. For decades antidepressant agents were based on the monoamine theory. Although ketamine may not be the golden antidepressant, it has opened new avenues toward mechanisms involved in the pathology of treatment-resistant depression and achieving rapid antidepressant effects. Thus, preclinical studies focusing on deciphering the molecular mechanisms involved in the antidepressant action of ketamine will assist in the development of a new antidepressant. This review was conducted to elucidate the emerging pathways that can explain the complex dose-dependent mechanisms achieved by administering ketamine to treat major depressive disorders. Special attention was paid to reviewing the literature on hydroxynorketamines, which are ketamine metabolites that have recently attracted attention in the context of depression.
Inhibition of Drp1 Sensitizes Cancer Cells to Cisplatin-Induced Apoptosis through Transcriptional Inhibition of c-FLIP Expression
Authors: Woo Seon Min , Min Kyoung-jin , Kwon Taeg Kyu
Published: December 2020

Mitochondrial fragmentation occurs during the apoptosis. Dynamin-related protein 1 (Drp1) acts as an important component in mitochondrial fission machinery and can regulate various biological processes including apoptosis, cell cycle, and proliferation. The present study demonstrates that dysfunction of mitochondrial dynamics plays a pivotal role in cisplatin-induced apoptosis. Inhibiting the mitochondrial fission with the specific inhibitor (Mdivi-1) did not affect apoptotic cell death in low concentrations (<10 μM). Interestingly, mdivi-1 enhanced cisplatin-induced apoptosis in cancer cells, but not in normal cells. Particularly in the presence of mdivi-1, several human cancer cell lines, including renal carcinoma cell line Caki-1, became vulnerable to cisplatin by demonstrating the traits of caspase 3-dependent apoptosis. Combined treatment induced downregulation of c-FLIP expression transcriptionally, and ectopic expression of c-FLIP attenuated combined treatment-induced apoptotic cell death with mdivi-1 plus cisplatin. Collectively, our data provide evidence that mdivi-1 might be a cisplatin sensitizer.
Antioxidant Property of the Egyptian Propolis Extract Versus Aluminum Silicate Intoxication on a Rat’s Lung: Histopathological Studies
Authors: Abu Almaaty Ali H. , Abd El-Aziz Yasmin M. , Omar Nahed A. , Abdeen Ahmed M. , Afifi Hala , Ibrahim Tarek S. , Elhady Sameh S. , Khedr Amgad I. M.
Published: December 2020

In this study, we evaluated the inflammatory responses induced by aluminum silicate (AS) cytotoxicity in rat lungs. The prophylactic effect of propolis extract was evaluated in 60 adult male albino rats. The rats were divided into six groups: (1) a normal, healthy control group; (2) a normal group fed with 200 mL of propolis extract/Kg; (3) a low-dose positive control group injected with 5 mg/kg of AS; (4) a treated group given propolis and a low dose of AS; (5) a high-dose positive control group injected with 20 mg/kg of AS; and (6) a treated group given propolis with a high-dose of AS. At the end of the two-month experiment, the rats’ lungs were removed. For each pair of lungs, one portion was subjected to biochemical analysis and the other underwent hematoxylin and eosin (H&E) staining in order to study its histology. The rats that received AS doses displayed significant disorders in their antioxidant contents as well as in their enzymatic activities and their histopathological structures revealed severe damage to their lung tissues. Upon the rats being treated with propolis, the enzymatic and antioxidant contents improved and partial improvements in the lung structures appeared, including minimized congestion, a reduced hemorrhage of blood vessels and preserved bronchioles, alveolar ducts, and alveoli. The prophylactic effectiveness of propolis extract on the cytotoxicity of AS, owing to the antioxidant properties of propolis, were studied.
Recent Strategies and Applications for l-Asparaginase Confinement
Authors: Nunes João C. F. , Cristóvão Raquel O. , Freire Mara G. , Santos-Ebinuma Valéria C. , Faria Joaquim L. , Silva Cláudia G. , Tavares Ana P. M.
Published: December 2020

l-asparaginase (ASNase, EC 3.5.1.1) is an aminohydrolase enzyme with important uses in the therapeutic/pharmaceutical and food industries. Its main applications are as an anticancer drug, mostly for acute lymphoblastic leukaemia (ALL) treatment, and in acrylamide reduction when starch-rich foods are cooked at temperatures above 100 °C. Its use as a biosensor for asparagine in both industries has also been reported. However, there are certain challenges associated with ASNase applications. Depending on the ASNase source, the major challenges of its pharmaceutical application are the hypersensitivity reactions that it causes in ALL patients and its short half-life and fast plasma clearance in the blood system by native proteases. In addition, ASNase is generally unstable and it is a thermolabile enzyme, which also hinders its application in the food sector. These drawbacks have been overcome by the ASNase confinement in different (nano)materials through distinct techniques, such as physical adsorption, covalent attachment and entrapment. Overall, this review describes the most recent strategies reported for ASNase confinement in numerous (nano)materials, highlighting its improved properties, especially specificity, half-life enhancement and thermal and operational stability improvement, allowing its reuse, increased proteolysis resistance and immunogenicity elimination. The most recent applications of confined ASNase in nanomaterials are reviewed for the first time, simultaneously providing prospects in the described fields of application.
Possibilities for Optimization of Industrial Alkaline Steeping of Wood-Based Cellulose Fibers
Authors: Fechter Catharina , Brelid Harald , Fischer Steffen
Published: December 2020

Steeping of cellulosic materials in aqueous solution of NaOH is a common pre-treatment in several industrial processes for production of cellulose-based products, including viscose fibers. This study investigated whether the span of commonly applied process settings has the potential for process optimization regarding purity, yield, and degree of transformation to alkali cellulose. A hardwood kraft dissolving pulp was extracted with 17–20 wt% aq. NaOH at 40−50 °C. The regenerated residue of the pulp was characterized regarding its chemical composition, molecular structure, and cellulose conformation. Yield was shown to be favored primarily by low temperature and secondly by high alkali concentration. Purity of xylan developed inversely. Both purity of xylan and yield varied over the applied span of settings to an extent which makes case-adapted process optimization meaningful. Decreasing the steeping temperature by 2 °C increased xylan content in the residue with 0.13%-units over the whole span of applied alkali concentrations, while yield increased by 0.15%-units when extracting with 17 wt% aq. NaOH, and by 0.20%-units when extracting with 20 wt%. Moreover, the yield-favoring conditions resulted in a narrower molecular weight distribution. The degree of transformation via alkali cellulose to cellulose II, as determined with Raman spectroscopy, was found to be high at all extraction settings applied.
In Situ Determination of Nitrate in Water Using Fourier Transform Mid-Infrared Attenuated Total Reflectance Spectroscopy Coupled with Deconvolution Algorithm
Authors: Gan Fangqun , Wu Ke , Ma Fei , Du Changwen
Published: December 2020

Fourier transform infrared attenuated total reflectance (FTIR-ATR) spectroscopy has been used to determine the nitrate content in aqueous solutions. However, the conventional water deduction algorithm indicated considerable limits in the analysis of samples with low nitrate concentration. In this study, FTIR-ATR spectra of nitrate solution samples with high and low concentrations were obtained, and the spectra were then pre-processed with deconvolution curve-fitting (without water deduction) combined with partial least squares regression (PLSR) to predict the nitrate content. The results show that the typical absorption of nitrate (1200−1500 cm−1) did not clearly align with the conventional algorithm of water deduction, while this absorption was obviously observed through the deconvolution algorithm. The first principal component of the spectra, which explained more than 95% variance, was linearly related to the nitrate content; the correlation coefficient (R2) of the PLSR model for the high-concentration group was 0.9578, and the ratio of the standard deviation of the prediction set to that of the calibration set (RPD) was 4.22, indicating excellent prediction performance. For the low-concentration group model, R2 and RPD were 0.9865 and 3.15, respectively, which also demonstrated significantly improved prediction capability. Therefore, FTIR-ATR spectroscopy combined with deconvolution curve-fitting can be conducted to determine the nitrate content in aqueous solutions, thus facilitating rapid determination of nitrate in water bodies with varied concentrations.
Excellent, Lightweight and Flexible Electromagnetic Interference Shielding Nanocomposites Based on Polypropylene with MnFe2O4 Spinel Ferrite Nanoparticles and Reduced Graphene Oxide
Authors: Yadav Raghvendra Singh , Anju  , Jamatia Thaiskang , Kuřitka Ivo , Vilčáková Jarmila , Škoda David , Urbánek Pavel , Machovský Michal , Masař Milan , Urbánek Michal , Kalina Lukas , Havlica Jaromir
Published: December 2020

In this work, various tunable sized spinel ferrite MnFe2O4 nanoparticles (namely MF20, MF40, MF60 and MF80) with reduced graphene oxide (RGO) were embedded in a polypropylene (PP) matrix. The particle size and structural feature of magnetic filler MnFe2O4 nanoparticles were controlled by sonochemical synthesis time 20 min, 40 min, 60 min and 80 min. As a result, the electromagnetic interference shielding characteristics of developed nanocomposites MF20-RGO-PP, MF40-RGO-PP, MF60-RGO-PP and MF80-RGO-PP were also controlled by tuning of magnetic/dielectric loss. The maximum value of total shielding effectiveness (SET) was 71.3 dB for the MF80-RGO-PP nanocomposite sample with a thickness of 0.5 mm in the frequency range (8.2–12.4 GHz). This lightweight, flexible and thin nanocomposite sheet based on the appropriate size of MnFe2O4 nanoparticles with reduced graphene oxide demonstrates a high-performance advanced nanocomposite for cutting-edge electromagnetic interference shielding application.
UV-B Radiation Affects Photosynthesis-Related Processes of Two Italian Olea europaea (L.) Varieties Differently
Authors: Piccini Chiara , Cai Giampiero , Dias Maria Celeste , Romi Marco , Longo Roberta , Cantini Claudio
Published: December 2020

Given the economical importance of the olive tree it is essential to study its responses to stress agents such as excessive UV-B radiation, to understand the defense mechanisms and to identify the varieties that are able to cope with it. In the light of the analysis carried out in this study, we argue that UV-B radiation represents a dangerous source of stress for the olive tree, especially in the current increasingly changing environmental conditions. Both the varieties considered (Giarraffa and Olivastra Seggianese), although resistant to the strong treatment to which they were exposed, showed, albeit in different ways and at different times, evident effects. The two varieties have different response times and the Giarraffa variety seems better suited to prolonged UV-B stress, possible due to a more efficient and quick activation of the antioxidant response (e.g., flavonoids use to counteract reactive oxygen species) and because of its capacity to maintain the photosynthetic efficiency as well as a relatively higher content of mannitol. Moreover, pigments reduction after a long period of UV-B exposure can also be an adaptation mechanism triggered by Giarraffa to reduce energy absorption under UV-B stress. Olivastra Seggianese seems less suited to overcome UV-B stress for a long period (e.g., higher reduction of Fv/Fm) and has a higher requirement for sugars (e.g., glucose) possible to counteract stress and to restore energy.
Abscisic Acid and Sulfate Offer a Possible Explanation for Differences in Physiological Drought Response of Two Maize Near-Isolines
Authors: Shekoofa Avat , Sinclair Thomas R.
Published: December 2020

The hypothesis was tested that differences in response to water-deficits between low osmotic potential (LOP) and high osmotic potential (HOP) maize (Zea mays L.) near-isolines were associated with differences in transpiration rate sensitivity to abscisic acid (ABA) and/or sulfate. In a series of four experiments, decreases in transpiration rate (DTR) of whole plants and fully expanded leaves were measured in response to treatments of 1.0 µM ABA and 15 mM MgSO4 singly and in combination following long (2 day) and short (180 min) exposures. There was little evidence that intact plants grown on soil were responsive to the treatments. For hydroponically grown plants subjected to long exposure, there was similarly no response to treatments. Further, the short exposure of hydroponically grown plants to solely ABA or a combination of chemicals resulted in no sensitivity in DTR for either of the near-isolines. On the other hand, when these plants were fed sulfate, the transpiration was stimulated by about 20% for the LOP and 60% for the HOP. Detached leaves proved to be the most sensitive to treatment. Treatment with the two chemicals singly caused essentially equivalent DTR in the two near-isolines. However, treatment with ABA plus sulfate resulted in different DTR between the two near-isolines with values of 65% for the LOP and 16% for the HOP near-isoline. Overall, these results showed that the short exposure treatment of hydroponically grown plants or detached leaves supported the hypothesis of different transpiration rate sensitivities of the near-isolines in response to ABA and sulfate treatments.
Taxonomy of the Genus Halophila Thouars (Hydocharitaceae): A Review
Authors: Kuo John
Published: December 2020

The seagrass genus Halophila Thouars has more than twenty described species and is predominately distributed over a wide geographic range along the tropical and the warm temperate coastlines in the Indo-West Pacific Oceans. A brief history of the Halophila taxonomic development is presented. Based on reproductive and vegetative morphology, the genus is divided into eight sections including three new sections: section Australes, section Stipulaceae and section Decipientes. A rewritten taxonomic description of the type species for the genus Halophila,H. madagascariensis Steudel ex Doty et B.C. Stone, is provided. The lectotype of H. engelmannii Asch. as well as neotypes of H. hawaiiana Doty et B.C. Stone and H. spinulosa (Br.) Asch. are designated. Furthermore, H. ovalis ssp. bullosa, ssp. ramamurthiana and ssp. linearis together with H. balforurii have been recognised as distinct species. Nomenclature, typification, morphological description and botanical illustrations are presented for each taxon. Recent molecular phylogenetic surveys on certain Halophila taxa are also discussed. Field surveys for the deep water Halophila in West Pacific regions are suggested. Morphological studies combined with molecular investigations for the Halophila on the east coast of Africa and the West Indian Ocean are urgently needed and highly recommended.
Comparative Technical Process and Product Assessment of Catalytic and Thermal Pyrolysis of Lignocellulosic Biomass
Authors: Patel Akshay D. , Zabeti Masoud , Seshan K. , Patel Martin K.
Published: December 2020

Availability of sustainable transportation fuels in future hinges on the use of lignocellulosic resources for production of biofuels. The process of biomass pyrolysis can be used to convert solid biomass resources into liquid fuels. In this study, laboratory experiments and process simulations were combined to gain insight into the technical performance of catalytic and thermal pyrolysis processes. Waste pinewood was used as a feedstock for the processes. The pyrolysis took place at 500 °C and employs three different catalysts, in the case of the catalytic processes. A process model was developed with Aspen Plus and a wide range of representative components of bio-oil were used to model the properties of the bio-oil blend. The results of the process model calculations show that catalytic pyrolysis process produces bio-oil of superior quality. Different technical process scenarios were explored based on the properties of the bio-oil after separation of water-soluble components, with the intention of producing a blendable or stand-alone product. It was found that—depending on the bio-oil requirements—sufficient hydrogen can be made available from the aqueous fraction to further treat the organic fraction to the desired extent. The resulting organic fractions are suitable candidates for blending with conventional fuels. The analysis results are used to provide guidance for catalyst development.
Synthesis of 2-(4-hydroxyphenyl)ethyl 3,4,5-Trihydroxybenzoate and Its Inhibitory Effect on Sucrase and Maltase
Authors: Li Wen-Tai , Chuang Yu-Hsuan , Liao Jiahn-Haur , Hsieh Jung-Feng
Published: December 2020

We report on the synthesis of an active component, 2-(4-hydroxyphenyl)ethyl 3,4,5-trihydroxybenzoate (HETB), from Rhodiola crenulata. Subsequent analysis revealed that HETB exhibits α-glucosidase inhibitory activities on maltase and sucrase, with potency exceeding that of the known α-glucosidase inhibitors (voglibose and acarbose). An inhibition kinetics study revealed that HETB, acarbose, and voglibose bind to maltase and sucrase, and HETB was shown to be a strong competitive inhibitor of maltase and sucrase. In a molecular docking study based on the crystal structure of α-glucosidase from Saccharomyces cerevisiae, we revealed the HETB binding in the active site of maltase via hydrogen-bond interactions with five amino acid residues: Ser 240, Asp 242, Glu 277, Arg 315, and Asn 350. For HETB docked to the sucrase active site, seven hydrogen bonds (with Asn 114, Glu 148, Gln 201, Asn 228, Gln 381, Ile 383, and Ser 412) were shown.
Numerical Study on Bubble Rising in Complex Channels Saturated with Liquid Using a Phase-Field Lattice-Boltzmann Method
Authors: Yu Kang , Yong Yumei , Yang Chao
Published: December 2020

Packed bed reactors have been widely applied in industrial production, such as for catalytic hydrogenation. Numerical simulations are essential for the design and scale-up of packed beds, especially direct numerical simulation (DNS) methods, such as the lattice-Boltzmann method (LBM), which are the focus of future researches. However, the large density difference between gas and liquid in packed beds often leads to numerical instability near phase interface when using LBM. In this paper, a lattice-Boltzmann (LB) model based on diffuse-interface phase-field is employed to simulate bubble rising in complex channels saturated with liquid, while the numerical problems caused by large liquid-to-gas density ratio are solved. Among them, the channel boundaries are constructed with regularly arranged circles and semicircles, and the bubbles pass through the channels accompanied by deformation, breakup, and coalescence behaviors. The phase-field LB model is found to exhibit good numerical stability and accuracy in handing the problem of the bubbles rising through the high-density liquid. The effects of channel structures, gas-liquid physical properties, and operating conditions on bubble deformation, motion velocity, and drag coefficient are simulated in detail. Moreover, different flow patterns are distinguished according to bubble behavior and are found to be associated with channel structure parameters, gravity Reynolds number (ReGr), and Eötvös number (Eo).
Methanol in Grape Derived, Fruit and Honey Spirits: A Critical Review on Source, Quality Control, and Legal Limits
Authors: Botelho Goreti , Anjos Ofélia , Estevinho Letícia M. , Caldeira Ilda
Published: December 2020

Spirits are alcoholic beverages commonly consumed in European countries. Their raw materials are diverse and include fruits, cereals, honey, sugar cane, or grape pomace. The main aim of this work is to present and discuss the source, quality control, and legal limits of methanol in spirits produced using fruit and honey spirits. The impact of the raw material, alcoholic fermentation, and the distillation process and aging process on the characteristics and quality of the final distilled beverage are discussed. In addition, a critical view of the legal aspects related to the volatile composition of these distillates, the origin and presence of methanol, and the techniques used for quantification are also described. The methanol levels found in the different types of spirits are those expected based on the specific raw materials of each and, almost in all studies, respect the legal limits.
Economic and Environmental Assessment of Catalytic and Thermal Pyrolysis Routes for Fuel Production from Lignocellulosic Biomass
Authors: Patel Akshay D. , Zabeti Masoud , Seshan K. , Patel Martin K.
Published: December 2020

Meeting the transport needs of a growing world population makes it imperative to develop renewable and sustainable routes to production of liquid fuels. With a market-driven economic structure and pressing environmental issues, it is essential that these new routes provide environmental benefits while being economically viable. Conversion of second-generation lignocellulosic biomass resources to fuels via pyrolysis represents an important technological route. In this article, we report comparative assessment of the economic and lifecycle environmental aspects for catalytic and thermal pyrolysis. The goal of this assessment is two-fold: one is to understand the potential of this conversion route via the catalytic and thermal processes and second is to provide feedback for further development of catalysts for various stages of this conversion. The complete assessment is interdisciplinary in nature and connects the laboratory experiments with contextual sustainability assessment. Three catalytic and one thermal pyrolysis processes are analyzed using this assessment approach. Subject to the model choices and data inputs, the results, which consider quality of the oil product, show that biofuels produced using catalytic and thermal routes are rather expensive compared to gasoline. But at the same time, they provide significant greenhouse gas emission savings and can lead to lower CO2 abatement costs compared to the first-generation ethanol that is used currently. With one of the product scenarios of hydrotreated (HT) oil, the abatements costs are estimated to be 51% of those associated with first-generation ethanol. Additional product scenarios with developments in catalysts show potential to further reduce abatement costs significantly to below 100 EUR per metric tonne of CO2 equivalents. Using scenario analysis, the results help us to understand specific areas for development of novel catalysts. At the same time, the results demonstrate the trade-offs associated with the variety and complexity of technical factors associated with the pyrolysis routes. The study highlights the challenges and the promises of catalytic and thermal pyrolysis for production of high-quality biofuels produced via a sustainable production route.
Functionality of Special Beer Processes and Potential Health Benefits
Authors: Salanță Liana Claudia , Coldea Teodora Emilia , Ignat Maria Valentina , Pop Carmen Rodica , Tofană Maria , Mudura Elena , Borșa Andrei , Pasqualone Antonella , Anjos Ofélia , Zhao Haifeng
Published: December 2020

Consumers’ demand for functional fermented food that can fulfill nutritional needs and help maintain a balanced diet while also having a positive impact on one’s health status is increasing all over the world. Thus, healthy choices could include beverages with nutrients and bioactive compounds which can be used as an effective disease-prevention strategy. Regular beer has certain health benefits which inspire further research with the prospect of obtaining special functional beers with little or no alcohol content. As observed, the special beer market remains highly dynamic and is predicted to expand even further. Therefore, brewers need to keep up with the consumers’ interests and needs while designing special beers, namely nonalcoholic beers (NABs), low-alcohol beers (LABs), and craft beers (CBs). Thus, understanding the potential uses of bioactive compounds in special beer, the wide range of therapeutic effects, and the possible mechanisms of action is essential for developing healthier beverages. This review aimed to evaluate the nutritional features of special beers, and their proven or potential beneficial actions on one’s health status and in preventing certain diseases.
Numerical Simulation on the Brake Effect of FAC-EMBr and EMBrRuler in the Continuous Casting Mold
Authors: Li Zhuang , Zhang Lintao , Bao Yanming , Ma Danzhu
Published: December 2020

The brake effect of the freestanding adjustable combination electromagnetic brake (FAC-EMBr) and EMBr ruler on the behavior of molten steel flow and the level fluctuation were investigated with the numerical method. The effects of the horizontal magnetic pole position (EMBr ruler), magnetic induction intensity, and casting speed on two types of electromagnetic brakes were studied. The numerical simulation results show that the magnetic field caused by the EMBr ruler is mainly distributed under the submerged entry nozzle (SEN), and it is very weak nearby the meniscus area. After the FAC-EMBr is applied, the magnetic field is mainly distributed in the area below the submerged entry nozzle, the upper roll region, and in the meniscus region. The application of the electromagnetic brake can effectively suppress the impact of the jet and decrease the molten steel velocity in the meniscus area. The brake effect of the EMBr ruler on the behavior of the molten steel flow and the level fluctuation is significantly influenced by the horizontal magnetic pole position. The increasing of the magnetic flux density can significantly increase the velocity of molten steel in the upper roll region and lead to an intense fluctuation in the steel/slag interface, as the horizontal magnetic field cannot cover the three key regions. The brake effect of the FAC-EMBr is less influenced by the variation of the process parameters due to the addition of vertical magnetic poles. Additionally, the “secondary braking effect” of the vertical magnetic poles can help to lower the increase of velocity in the upper roll region caused by the excessive magnetic induction intensity and the high casting speed. Therefore, even under the high casting speed conditions, the application of a new type of FAC-EMBr is also an efficient way to suppress the molten steel flow and level fluctuation at the meniscus area and decrease the possibility of slag entrapment.
Eulerian Multiphase Simulation of the Particle Dynamics in a Fluidized Bed Opposed Gas Jet Mill
Authors: Araújo dos Santos Dyrney , Baluni Shivam , Bück Andreas
Published: December 2020

The compressible and turbulent gas–solid multiphase flow inside a fluidized bed opposed jet mill was systematically investigated through numerical simulations using the Euler–Euler approach along with the kinetic theory of granular flow and frictional models. The solid holdup and nozzle inlet air velocity effects on the gas–solid dynamics were assessed through a detailed analysis of the time-averaged volume fraction, the time-averaged velocity, the time-averaged streamlines, and the time-averaged vector field distributions of both phases. The simulated results were compared with the experimental observations available in the literature. The numerical simulations contributed to a better understanding of the particle–flow dynamics in a fluidized bed opposed gas jet mill which are of fundamental importance for the milling process performance.
Is Steam Explosion a Promising Pretreatment for Acid Hydrolysis of Lignocellulosic Biomass?
Authors: Steinbach David , Kruse Andrea , Sauer Jörg , Storz Jonas
Published: December 2020

For the production of sugars and biobased platform chemicals from lignocellulosic biomass, the hydrolysis of cellulose and hemicelluloses to water-soluble sugars is a crucial step. As the complex structure of lignocellulosic biomass hinders an efficient hydrolysis via acid hydrolysis, a suitable pretreatment strategy is of special importance. The pretreatment steam explosion was intended to increase the accessibility of the cellulose fibers so that the subsequent acid hydrolysis of the cellulose to glucose would take place in a shorter time. Steam explosion pretreatment was performed with beech wood chips at varying severities with different reaction times (25–34 min) and maximum temperatures (186–223 °C). However, the subsequent acid hydrolysis step of steam-exploded residue was performed at constant settings at 180 °C with diluted sulfuric acid. The concentration profiles of the main water-soluble hydrolysis products were recorded. We showed in this study that the defibration of the macrofibrils in the lignocellulose structure during steam explosion does not lead to an increased rate of cellulose hydrolysis. So, steam explosion is not a suitable pretreatment for acid hydrolysis of hardwood lignocellulosic biomass.
Top-Down Estimation of Particulate Matter Emissions from Extreme Tropical Peatland Fires Using Geostationary Satellite Fire Radiative Power Observations
Authors: Fisher Daniel , Wooster Martin J. , Xu Weidong , Thomas Gareth , Lestari Puji
Published: December 2020

Extreme fires in the peatlands of South East (SE) Asia are arguably the world’s greatest biomass burning events, resulting in some of the worst ambient air pollution ever recorded (PM10 > 3000 µg·m−3). The worst of these fires coincide with El Niño related droughts, and include huge areas of smouldering combustion that can persist for months. However, areas of flaming surface vegetation combustion atop peat are also seen, and we show that the largest of these latter fires appear to be the most radiant and intensely smoke-emitting areas of combustion present in such extreme fire episodes. Fire emissions inventories and early warning of the air quality impacts of landscape fire are increasingly based on the fire radiative power (FRP) approach to fire emissions estimation, including for these SE Asia peatland fires. “Top-down” methods estimate total particulate matter emissions directly from FRP observations using so-called “smoke emission coefficients” [Ce; g·MJ−1], but currently no discrimination is made between fire types during such calculations. We show that for a subset of some of the most thermally radiant peatland fires seen during the 2015 El Niño, the most appropriate Ce is around a factor of three lower than currently assumed (~16.8 ± 1.6 g·MJ−1 vs. 52.4 g·MJ−1). Analysis indicates that this difference stems from these highly radiant fires containing areas of substantial flaming combustion, which changes the amount of particulate matter emitted per unit of observable fire radiative heat release in comparison to more smouldering dominated events. We also show that even a single one of these most radiant fires is responsible for almost 10% of the overall particulate matter released during the 2015 fire event, highlighting the importance of this fire type to overall emission totals. Discriminating these different fires types in ways demonstrated herein should thus ultimately improve the accuracy of SE Asian fire emissions estimates derived using the FRP approach, and the air quality modelling which they support.
Comparison of Machine Learning Algorithms for Structure State Prediction in Operational Load Monitoring
Authors: Mucha Waldemar
Published: December 2020

The aim of operational load monitoring is to make predictions about the remaining usability time of structures, which is extremely useful in aerospace industry where in-service life of aircraft structural components can be maximized, taking into account safety. In order to make such predictions, strain sensors are mounted to the structure, from which data are acquired during operational time. This allows to determine how many load cycles has the structure withstood so far. Continuous monitoring of the strain distribution of the whole structure can be complicated due to vicissitude nature of the loads. Sensors should be mounted in places where stress and strain accumulations occur, and due to experiencing variable loads, the number of required sensors may be high. In this work, different machine learning and artificial intelligence algorithms are implemented to predict the current safety factor of the structure in its most stressed point, based on relatively low number of strain measurements. Adaptive neuro-fuzzy inference systems (ANFIS), support-vector machines (SVM) and Gaussian processes for machine learning (GPML) are trained with simulation data, and their effectiveness is measured using data obtained from experiments. The proposed methods are compared to the earlier work where artificial neural networks (ANN) were proven to be efficiently used for reduction of the number of sensors in operational load monitoring processes. A numerical comparison of accuracy and computational time (taking into account possible real-time applications) between all considered methods is provided.
Integrating Biosignals Measurement in Virtual Reality Environments for Anxiety Detection
Authors: Petrescu Livia , Petrescu Cătălin , Mitruț Oana , Moise Gabriela , Moldoveanu Alin , Moldoveanu Florica , Leordeanu Marius
Published: December 2020

This paper proposes a protocol for the acquisition and processing of biophysical signals in virtual reality applications, particularly in phobia therapy experiments. This protocol aims to ensure that the measurement and processing phases are performed effectively, to obtain clean data that can be used to estimate the users’ anxiety levels. The protocol has been designed after analyzing the experimental data of seven subjects who have been exposed to heights in a virtual reality environment. The subjects’ level of anxiety has been estimated based on the real-time evaluation of a nonlinear function that has as parameters various features extracted from the biophysical signals. The highest classification accuracy was obtained using a combination of seven heart rate and electrodermal activity features in the time domain and frequency domain.
Industrial Symbiosis in Insect Production—A Sustainable Eco-Efficient and Circular Business Model
Authors: PhI Chloé Phan Van , Walraven Maye , Bézagu Marine , Lefranc Maxime , Ray Clément
Published: December 2020

Insect meal (IM) is a source of high-quality protein for aquafeed while insect oil (IO) is a source of fatty acids used in monogastric feed with identical or better performance than premium fishmeal (FM) or vegetable oils (VOs) respectively. Although insects’ ability to feed on agricultural by-products and the entire valorization of insect products (IM, IO, frass) suggest insect production is sustainable, no studies have documented its environmental impact using industrial-scale production data. The present study is the first attributional life cycle assessment (A-LCA) based on data from an industrial-scale facility implementing an innovative symbiosis production model. This A-LCA was used to (i) assess the environmental performance of the symbiosis model vs. a no-symbiosis model and (ii) compare the environmental impacts of IM and IO production vs. their respective alternatives. The results revealed that the symbiosis model introduces a meaningful change in terms of environmental footprint by reducing CO2 emissions by 80% and fossil resources depletion by 83% compared to the no-symbiosis model. The higher sustainability of the IM and IO produced using the symbiosis model was also demonstrated, as CO2 emissions were reduced by at least 55% and 83% when compared to the best FM and VOs alternatives, respectively.
Green Restaurant Consumers’ Pride and Social Healthy Narcissism Influencing Self-Actualization and Self-Transcendence That Drive Customer Citizenship Behavior
Authors: Hwang Kumju , Lee Bora , Hahn Juhee
Published: December 2020

This study explored green restaurant consumers’ self-actualization and self-transcendence motivations that drive customer citizenship behavior (CCB). A survey of green restaurant consumers was administered, and structural equation modeling (SEM) analysis was performed. The findings indicate the presence of positive associations between pride and self-actualization, and healthy social narcissism and self-transcendence. This study also found a positive relationship between self-actualization and self-transcendence, and they are positively associated with CCB. Interestingly, the findings suggest that green restaurant consumers’ pride, self-actualization and CCB path is more dominant path vis-à-vis the path from healthy social narcissism mediated by self-transcendence to CCB.
VIBRODIAGNOSTICS OF HINGE ELEMENTS CAR SUSPENSION
Authors:   Orel State University, RODICHEV A.Yu. , TEBEKIN M.D. ,   Orel State University, GORIN A.V. ,   Orel State University, KOLPAKOVA S.V. ,   Orel State University
Published: December 2020

The article contains an analysis of failures of articulated elements of automotive equipment. The paper presents a mathematical model for changing the technical condition of the ball joint of automotive vehicles. A design scheme is proposed, assumptions and limitations for a mathematical model are determined. During the work, experimental and theoretical studies were carried out. To assess the reliability of the results obtained by theoretical methods, an experimental study was car-ried out on the developed installation using vibration methods.
THE CONCEPT OF A LEAN LABORATORY FOR STUDENTS OF TRANSPORTATION SPECIALTIES
Authors:   Orel State University, GRADYNOVA E.N. , TOKMAKOVA M.A. ,   Orel State University, USIKOVA I.G. ,   Orel State University, RODICHEVA I.V. ,   Orel State University
Published: December 2020

The concept of functioning of a technical laboratory for training students of transport spe-cialties, based on the principles of 5C, is proposed. The layout of work and training areas in the classroom is presented. An algorithm for conducting laboratory work has been developed, taking into account the latest requirements for the educational process of transport directions of training at the university.