bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of framework networks for sign detection in deep learning models
Authors:   Lviv Polytechnic National University, Pukach Pavlo
Published: February 2023

This paper analyzes and compares modern deep learning models for the classification of MRI images of the knee joint. An analysis of modern deep computer vision architectures for feature extraction from MRI images is presented. This analysis was used to create applied architectures of machine learning models. These models are aimed at automating the process of diagnosing knee injuries in medical devices and systems. This work is devoted to different types of feature detection framework networks for machine learning architectures that perform magnetic resonance imaging (MRI) image classification of the knee. The resulting models were evaluated on the MRNet validation dataset, calculating the metrics (ROC-AUC), prediction accuracy, F1 score, and Cohen’s K-Kappa. The results of this work also show that Cohen's Kappa metric is important for evaluating models on the MRNet architecture because it provides a deeper understanding of the classification decisions of each model.
Overview of deep learning and mobile edge computing in autonomous driving
Authors:   Lviv Polytechnic National University, Cui Tianyuan
Published: February 2023

In recent years, mobile edge computing and deep learning have attracted strong industry attention in the application scenario of autonomous driving. Mobile edge computing reduces the transmission delay of autonomous driving information by offloading computational tasks to edge servers to reduce the network load; deep learning can effectively improve the accuracy of obstacle detection, thereby enhancing the stability and safety of autonomous driving. This paper first introduces the basic concept and reference architecture of MEC and the commonly used model algorithms in deep learning, and then summarizes the applications of MEC and deep learning in autonomous driving from three aspects: target detection, path planning, and collision avoidance, and finally discusses and outlooks the problems and challenges in current research.
Optimization of the infrastructure of the distributed information system of goods accounting
Authors:   Lviv Polytechnic National University, Faizulin Oleh , Kis Yaroslav ,   Lviv Polytechnic National University
Published: February 2023

An existing goods accounting information system was assessed for possible infrastructure optimization. A various parts of the system were analyzed to improve infrastructure costs without having a significant degradation of non-functional requirements. Modeling of the optimized system was performed, and evaluation of the infrastructure costs was made. Several optimization directions were evaluated, analyzed and either recommended or rejected. As the result, the final information system model was designed which allows to achieve significant infrastructure cost savings by applying multiple optimizations.
HUBUNGAN PENYESUAIAN DIRI DENGAN STRES AKADEMIK DALAM MENJALANI PEMBELAJARAN TATAP MUKA TERBATAS DI ERA NEW NORMAL PADA SISWA KELAS XI IPS SMA NEGERI 1 LUBUK PAKAM T.A 2021/2022
Authors: Siregar Syaninda Putri Asyifa , Rahmulyani Rahmulyani
Published: February 2023

The purpose of this study was to determine the relationship between adjustment and academic stress in limited face-to-face learning for class XI IPS students at SMA N 1 Lubuk Pakam for the Academic Year 2021/2022. The method in this study is a quantitative method. The research population is the students of class XI IPS. Sampling in this study using purposive sampling by taking a sample of 88 students who are stressed. Data collection was carried out using a questionnaire. The validity and reliability of the instrument was obtained by product moment correlation. Hypothesis testing using Pearson's product moment formula with the help of SPSS for Windows. The results of the analysis showed r = 0.661 and Rsquare = 0.437 and a significant value of 0.000 (p <0.05). Based on these results, the research hypothesis was put forward: "There is a relationship between adjustment and academic stress". Given this negative relationship of -.661 it can be stated that self-adjustment related to academic stress in limited face-to-face learning for students of SMA N 1 Lubuk Pakam was accepted. It is recommended that limited face-to-face learning be carried out simultaneously with increasing students' self-adjustment so that students' academic stress can be controlled.
HUBUNGAN RESILIENSI DENGAN STRES AKADEMIK SELAMA PEMBELAJARAN TATAP MUKA TERBATAS SISWA KELAS XI IPS SMA NEGERI 12 MEDAN TAHUN AJARAN 2021/2022
Authors: Jaya Ahmad Chandra , Irawan Mirza
Published: February 2023

The method in this study is a quantitative method with a correlational research design. The purpose of this study was to link resilience with academic stress during limited face-to-face learning for class XI social studies students at SMA N 12 Medan in the 2021/2022 academic year. The population in this study were students in class XI social studies. Sampling in this study used random sampling by taking 25% of all students of class XI IPS SMA N 12 Medan. The sample size is 30 students. Data collection is done by using a questionnaire. The validity of the questionnaire was obtained by using the product moment correlation and the reliability test was obtained by using the Cronbach alpha test. Test the hypothesis using the Pearson product moment formula with the help of SPSS20 for Windows. The results of the analysis showed r = 0.605 and Rsquare = 0.366 and a significance value of 0.000 (p <0.05). Based on these results, a research hypothesis was proposed: "there is a relationship between resilience and academic stress". Given this negative relationship of -.605, it can be stated that resilience related to academic stress in limited face-to-face learning for students of SMA N 12 Medan is accepted. It is recommended that limited face-to-face learning be carried out simultaneously with increasing student resilience so that students' academic stress can be controlled.
What we need to know about conducting language revitalisation work - A literature review from sociolinguistic perspectives
Authors: Ting Chien
Published: February 2023

This article provides a critical review of literature relating to Indigenous language revitalisation, including an introduction that provides the sociolinguistic background on language endangerment, and makes a strong plea for language preservation work. In particular, this paper highlights the efforts required prior to conducting language revitalisation work by explaining language endangerment assessment criteria and the efforts entailed to carry out the work. In theorising language revitalisation, key concepts and vocabulary are explained, and thus, the content serves as an additional resource to PG students interested in research related to language and society.
Destellos de una memoria trans
Authors: Del Curto Macarena , Featherston Catalina
Published: February 2023

En el presente artículo nos proponemos abordar el Archivo de la Memoria Trans, tomando como corpus dos fotografías de su acervo. A partir de ellas, pretendemos analizar las prácticas de representación que se configuran en el archivo, reparando en la manera en que este mismo se presenta, sus lógicas de acceso y sus criterios de catalogación. Comprendemos que la posibilidad de proyectar una memoria trans aparece, desde lo íntimo, ligada a una fuerte reivindicación identitaria y constituye en sí misma un posicionamiento político.
Topical permethrin may increase blacklegged tick (Ixodes scapularis) repellency but is associated with cutaneous irritation in horses
Authors: Poh Karen C. , Cole Zoey T. , Smarsh Danielle N. , Springer Hayley R. , Kelly Kathleen , Kenny Laura B. , Machtinger Erika T.
Published: February 2023

OBJECTIVE

To evaluate the safety of repeated applications of permethrin concentrations (0% control, 1.5%, 5%, and 10%) to the necks and faces of horses and assess the efficacy and longevity of permethrin as an equine tick repellent.

ANIMALS

5 healthy adult Quarter Horses.

PROCEDURES

Each treatment was applied to the neck of each horse (0.01 m2) 4 times a day, for up to 10 days. An 8-mm biopsy was taken to evaluate postexposure dermal responses. Any treatments that were not withdrawn were applied to a quadrant of the horse’s face 4 times a day, for up to 5 days. For tick bioassays, a treatment was applied to 1 leg of a horse and 5 female blacklegged ticks (Ixodes scapularis) were evaluated as “repelled” or “not repelled” by the treatment. The bioassays were repeated up to 5 days, but treatment application took place only on the first day of the experiment.

RESULTS

Histological results of neck biopsies indicated that more repeated exposures or higher concentrations resulted in more dermal damage. Tick bioassays showed that 5% and 10% permethrin had the greatest efficacy and longevity as a tick repellent, but the differences in tick repellency were not significant overall.

CLINICAL RELEVANCE

While there was a nonsignificant trend of higher permethrin concentrations repelling more ticks with longer-lasting residual repellent effects, higher concentrations also produced greater skin damage after repeated exposures. These opposing findings emphasize the need for better tick prevention and control methods that balance safety and efficacy for the equine community.
The Asian and Balkan Background of Draculia’s Wallachian Restoration (1473-1474)
Authors: Pop Ioan Aurel , Simon Alexandru
Published: February 2023

Roughly a week before Ali Mihaloğlu, bey of Vidin and Smederevo, raided Oradea (February 7-8, 1474), the royal link between Hungary proper and the Voivodate of Transylvania, the Commune of Ragusa, equally vassal to Ottoman sultan Mehmed II and to Matthias Corvinus, king of Hungary, informed the Venetian doge, Nicolò Marcello, her Adriatic neighbour, about the most recent developments at the Porte, as well as both at the Porte’s Asian and European borders (January 31, 1474). From the latest news on Usun Hassan, still viewed by some as Christendom’s main anti-Ottoman hope (in spite of the crippling losses he had suffered in August 1473), Ragusa moved on – in her message to Venice (earlier Usun’s main supporter) – to the combats in Vlachia Maior (Wallachia proper), recently invaded by Stephen III the Great of Moldavia (November 8-30, 1473). The information had likewise been provided by the Ragusan envoys to the Porte, who had just returned to the Adriatic, after departing from Constantinople (Istanbul) on December 28, 1473. With Venice waging an increasingly desperate war against Mehmed II (for ten years and counting), the task of conveying Ottoman inside information was very delicate for tribute paying Ragusa.The Ragusan message is the only extant known source to state that Stephen III the Great had won Wallachia from Radu III the Handsome for the benefit of Vlad III the Impaller. The rest of the known sources (however chronicles, not documents) claim that Stephen enthroned Basarab III Laiotă as ruler of Wallachia (Laiotă was his Wallachian ruler of choice until autumn 1474).Ragusa’s Venetian message bluntly contradicts the known contemporary data on Stephen III’s intervention in Wallachia in November 1473 and on the subsequent events, data preserved only in the chronicles of Stephen III (chiefly in the Moldavian-German Chronicle intended for Habsburg subjects, around 1499-1500) and in the writings of Jan Długosz (notoriously hostile towards the Hunyadis).
CuO–Water MHD Mixed Convection Analysis and Entropy Generation Minimization in Double-Lid–Driven U-Shaped Enclosure with Discrete Heating
Authors: Mliki Bouchmel , Miri Rached , Djebali Ridha , Abbassi Mohamed A.
Published: February 2023

The present study explores magnetic nanoliquid mixed convection in a double lid–driven U-shaped enclosure with discrete heating using the lattice Boltzmann method (LBM) numerical method. The nanoliquid thermal conductivity and viscosity are calculated using the Maxwell and Brinkman models respectively. Nanoliquid magnetohydrodynamics (MHD) and mixed convection are analyzed and entropy generation minimisation has been studied. The presented results for isotherms, stream isolines and entropy generation describe the interaction between the various physical phenomena inherent to the problem including the buoyancy, magnetic and shear forces. The operating parameters’ ranges are: Reynolds number (Re: 1–100), Hartman number (Ha: 0–80), magnetic field inclination (γ: 0°– 90°), nanoparticles volume fraction (ϕ: 0–0.04) and inclination angle (α: 0°– 90°). It was found that the N

um
and the total entropy generation augment by increasing Re, ϕ: and γ. conversely, an opposite effect was obtained by increasing Ha and α. The optimum magnetic field and cavity inclination angles to maximum heat transfer are γ = 90° and α = 0.
Solution of the Modified Time Fractional Coupled Burgers Equations Using Laplace Adomian Decompostion Method
Authors: Omame Andrew , Zaman Fiazud Din
Published: February 2023

In this work, a coupled system of time-fractional modified Burgers’ equations is considered. Three different fractional operators: Caputo, Caputo-Fabrizio and Atangana-Baleanu operators are implemented for the equations. Also, two different scenarios are examined for each fractional operator: when the initial conditions are u(x, y, 0) = sin(xy), v(x, y, 0) = sin(xy), and when they are u(x, y, 0) = e{−kxy}, v(x, y, 0) = e{−kxy}, where k, α are some positive constants. With the aid of computable Adomian polynomials, the solutions are obtained using Laplace Adomian decomposition method (LADM). The method does not need linearization, weak nonlinearity assumptions or perturbation theory. Simulations are also presented to support theoretical results, and the behaviour of the solutions under the three different fractional operators compared.
Non-Formal Learning Activities – Adult Learning Initiatives
Authors: Simándi Szilvia
Published: February 2023

Introduction: The purpose of this paper is to contribute to the international history of community culture and culture-based adult learning through showing the initiatives of a Post-Socialist country through introducing some initiatives from 1950, without claim for completeness. Additions to the History of Community Culture and Culture-based Adult Education and Learning in Hungary.

Purpose: Our questions include how the political and legal environment, and the spread of the mass media influenced the cultural activities and the community culture, and what culture-based adult learning initiatives and activities can be identified in the area of culture.

Methods: To its realization we chose horizontal and vertical analysing viewpoints. The horizontal viewpoint of our investigation is the linearity of timeline, while the vertical analysing viewpoint is the characteristics of political and legal environment having influence on culture-based adult education (cf. non-formal and informal cultural learning) and showing the work of some significant personalities, through synthetizing archive sources and literature background.

Conclusions: The changing of the regime brought reform on this area, too, it basically changed the profession and the training as well: the community culture builds on local initiatives and active participation, includes the training, creating artistic, informational activity of the citizens, based on their self-activities.
On Writing and College Life: Rainbow Rowell’s Fangirl as a Campus Novel
Authors: Anténe Petr
Published: February 2023

In 2022, Rainbow Rowell’s Bildungsroman Fangirl (2013), listed among 10 recent campus novels by Michelle Carroll on PowellsBooks.Blog, may seem a somewhat nostalgic text, as it is set at the University of Nebraska in the 2011/12 academic year. While Fangirl has also been classified as a young adult novel, as a chronicle of the protagonist’s, Cath’s, first year at college, it may arouse memories of a comparable experience in any college graduate, academics included. Like many classic campus novels, Fangirl is concerned with the writing process, as the storyline focuses on a creative writing course Cath takes in her first semester. An author of fanfiction based on a Harry Potteresque fantasy, Cath submits a piece of her fanfiction as an assignment, and is shocked to be accused of plagiarism by her professor. Gradually, Cath’s progression to writing a different short story for the course parallels her learning to deal with family problems as well as her anxiety in the college environment that is new to her. In turn, not only does the novel not completely idealize college life, but it also highlights Cath’s need to negotiate her obligations as a student and her responsibilities outside campus.
Contemporary Black Campus Novels: Between Nostalgia and Counter-Nostalgia
Authors: Bacci Francesco
Published: February 2023

In its vast range of variants, the genre of the campus novel continues to thrive and be reinvented by contemporary writers. This essay focuses on a specific subgenre, the contemporary Black campus novel, and I intend to analyze compelling examples of the dualism of nostalgia and counter-nostalgia. While some of these campus-set stories are centered on, for example, murder mysteries and social satire, generally the Black campus novel has a more specific focus: the fictional and satirical representation of Black students and academics at university, constituting a window into the social-political events.

With the support of literary and sociological works such as Derek C. Maus’s Post-Soul Satire and Elaine Showalter’s Faculty Towers, I scrutinize Paul Beatty’s The White Boy Shuffle (1996), Zadie Smith’s On Beauty (2005), and Brandon Taylor’s Real Life (2020). While Beatty’s novel creates a post-soul satire (Maus) of the contradictory aspects of US colleges and their effect on African American students, Smith’s On Beauty and Taylor’s Real Life are more centered on nostalgic elements of the coming-of-age process of students coming to terms with their sexuality, family, and their professional future. My article intends to navigate what Janice Rossen calls “a complicated web [that] can be discerned in the texture of university fiction.”
“Brexit from the Campus”: Jonathan Coe’s Middle England
Authors: Mengel Ewald
Published: February 2023

The title of my article bears a double meaning. On the one hand, it refers to a group of Conservative politicians around Boris Johnson who studied at Oxford University in the eighties and who are identified in Jonathan Coe’s novel as the engineers behind the Brexit; on the other hand, Coe’s novel portrays a fictional group of scholars who are more or less frustrated and dissatisfied with the university for various reasons and turn their backs on academia to find their luck elsewhere. In the first case, Oxford colleges such as Balliol where people are nostalgically hankering after England’s glorious past and dream of regaining England’s former glory, play a role as seedbed of Brexit; in the second case, we are dealing with a more private ‘exit’ of a group of talented academicians who no longer believe in the university as a place of self-realization. While nostalgia is a driving force of the first group, the second has a clear-eyed view of the growing hostility of their environment. Historically speaking, the existence of nostalgia here and the lack of nostalgia there are two sides of the same medal: they point to the heritage of the Thatcher era and the deep-reaching ‘reformation’ of British society whose effects can still be felt today. They also point to loss: the loss of social consensus in the first case, and the loss of what the university and a university career once stood for.
Nostalgia for the Belief in a Female-Friendly Academic World to Come
Authors: Perkowska-Gawlik Elżbieta
Published: February 2023

In the academic novel of the 1980s, which Elaine Showalter dubs the feminist towers, women characters are not limited to beautiful and seductive students or faculty wives, whose husbands’ academic career appears to be also their own goal. Although the very presence of women in academia is often interpreted as a threat to the male reign over the ‘small world,’ female scholars are determined to expose and fight against gender inequity and inequality in order to be perceived and valued as fully-fledged scholars. Paradoxically, even if women are considered serious candidates for different university positions, they cannot indulge in the same intense pleasures of academic life as their male counterparts due to the overpowering feeling of being the other.

An analysis of female scholar characters and their diverse attitudes towards feminism is based on two academic mystery novels written in the 1980s, Death in a Tenured Position by Amanda Cross and Graves in Academe by Susan Kenney. It is followed by an investigation of the reasons making academics feel nostalgia for the university of the 1980’s, i.e. the milieu before the emergence of the protective power of the Me Too movement and reports on sexual harassment of women in academia published by the NASEM.
Impact of the covid-19 pandemic on the activities and implementation of polish research institutes and their statutory activities in 2020–2021
Authors: Barcikowska Renata
Published: February 2023

This is a research article whose main objective is to discuss the impact of the COVID-19 pandemic on the activities of research institutes in Poland. The sources of the paper are the results of surveys conducted twice in 2020, on a selected sample of research institutes associated with the Main Council of Research Institutes. For the purposes of the article, surveys of the literature and available sources were made, and the method of analysis and synthesis was applied. The article closes with a summary containing the most important conclusions.
The innovative potential of scientific and research units in the process of entrepreneurial discovery — examples from selected eu regions
Authors: Bednarczyk Gabriel , Trzmielak Dariusz M.
Published: February 2023

The entrepreneurial discovery process (EDP) is an element of the Research and Innovation Strategy for Smart Specialisation (RIS3) concept, which is the basis for activities carried out in European Union (EU) regions in the area of innovation policies. The process requires the creation of an institutional structure (cooperation network) that allows for coordinated and continuous cooperation between representatives of entities that create regional innovation systems. These include: authorities, scientific and research units, entrepreneurs and civil society. The purpose of this article is to present the role of scientific and research units in the cooperation network, as well as the possibility of using their innovation potential when conducting EDP. On the basis of market research in 10 regions, the authors identified practical examples of cooperation carried out in selected seven EU regions (partner regions participating in a project calledBeyond EDP).
Decision-making Algorithm for Waste Recovery Options. Review on Textile Waste Derived Products
Authors: Zandberga Anda , Kalnins Silvija Nora , Gusca Julija
Published: February 2023

As the volume of textile waste steadily increases, mechanical, chemical and biological technologies for textile waste recovery are evolving. Also, the legal framework of the European Union has stated the commitments for promoting the recycling of textile waste in the Member States. So far, however, no decision-making algorithms have been developed for the selection of products recovered from textile waste. Within the present study, a hybrid multi-criteria decision-making algorithm for evaluating textile waste recovered products has been developed applying seven circular economic criteria – ‘Circular economy approach of the technology’, ‘Added-value potential of final product’, ‘Share of textile waste in total waste feedstock’, ‘Diversity of textile mix suitable for specific technology’, ‘Pre-treatment of waste feedstock’, ‘Recovery potential’ and ‘Maturity of a recovery technology’. The weighting of the criteria was determined by eight waste management experts. The results of the expert-based criteria evaluation show that the most important criteria are ‘Added-value potential of final product’ and ‘Circular economy approach of the technology’. The developed decision-making methodology has been adapted to nine textile waste recovered products – compost, refuse-derived fuel, ethanol, glucose, building insulation material from cement and textile waste mix, building insulation material from denim textile waste, terephthalic acid, recovered cotton and recovered polyester. The multi-criteria, decision-making ranking of the products textile shows that the highest potential for products recovered from textile waste is for glucose and terephthalic acid, while the lowest – for ethanol, compost and refuse-derived fuel.
The use of comparative market coefficients to measure office property market and fair values: Some special aspects
Authors: YAKUPOVA Nailya M. , KLYCHOVA Guzaliya S. , LEVACHKOVA Svetlana Yu. , SAIFEEVA Elena B.
Published: February 2023

Subject. This article deals with the issues of assessing the market value of office real estate.
Objectives. The article aims to substantiate the need to use special calculated values of multipliers differentiated by the main cost factors.
Methods. The study is based on the verification of the considered methods of valuation of office real estate on the basis of pair and multiple regression methods, as well as the theoretical and methodological aspects of assessing the value of office real estate, in particular, on the application of the gross rent multiplier (GRM) method. We also used general scientific methods of cognition, empirical and economic analysis methods, methods of scientific abstraction, comparison, classification, generalization, grouping, and graphic analysis.
Results. The article identifies the main factors in determining the value of office real estate, analyzes the values of the office real estate objects’ value by published multipliers and various calculated types of multipliers, and also it compares the values obtained. It focuses on the fact that the value of office real estate obtained on the basis of published values of gross rent multipliers, is underestimated. The article also justifies the need to use multipliers that are more detailed in terms of cost factors.
Special knowledge of an expert economist in the field of budget security of Russia
Authors: ZHIL’TSOVA Yuliya V.
Published: February 2023

Subject. This article explores the role of the public sector in the Russian economy and the problem of improving the quality of forensic economical examination.
Objectives. The article aims to identify and systematize the differences between accounting and reporting of enterprises in the commercial and public sectors of the economy, as well as study statistics on economic crimes in the public sector.
Methods. For the study, I used analysis, synthesis, and comparison.
Results. The article presents a systematization of the features of budget accounting and describes the characteristic features of unlawful acts in the budgetary sphere.
Conclusions. The results of the study can contribute to the competent compilation of the research part of the expert opinion and the obtaining of reasonable conclusions, which will optimize the judicial process as a whole.
Other Uses of Rhynchosia Roots Other Than For Processing Traditional Fermented Beverages in Zambia
Authors:   Zambia Agriculture Research Institute (ZARI), Private Bag 7, Chilanga Zambi, Zambia, Phiri Sydney
Published: February 2023

Rhynchosia roots commonly known as Munkoyo roots in Zambia are an important ingredient in the processing of cereal-based traditional fermented beverages called Munkoyo and Chibwantu
La ganadería en la baronía de Escornalbou, arzobispado de Tarragona (siglos XII-XV)
Authors:   Universitat Autònoma de Barcelona (España), Sarobe Huesca Ramon
Published: February 2023

This article is an approach to the livestock farming activities in the domain of Escornalbou (Catalonia, in the Baix Camp shire and municipality of Riudecanyes) during the late medieval centuries. After recounting the few known history and particularities of the Augustinian canons of the barony of Escornalbou, the lords of the place, the main features of the livestock explotation are narrated: The protections granted by the emprius (rights of use), the vicinity of the city of Tarragona, credits to the livestock purchasing operations, and the animal custody and care infrastructures as well. Animals present in the documents are also explained and the characteristics of their explotation. The canons of Escornalbou did not have a particular interest in the livestock economy, but their barony’s men considered it a serious business to be exploited with the only limit of their financial capacities.
PENGUKURAN PRODUKTIVITAS LANTAI PRODUKSI MENGGUNAKAN METODE OBJECTIVE MATRIX (OMAX) DI PT. XYZ
Authors: Komariah Imas
Published: February 2023

Produktivitas berperan penting dalam kelangsungan hidup sebuah perusahaan.PT XYZ berupaya meningkatkan produktivitas agar seluruh sumber daya dapat dimanfaatkan secara optimal. Penelitian ini melakukan pengukuran produktivitas di lantai produksi dengan menggunakan metode Objective Matrix (OMAX). Indikator pengukuran produktivitas melingkupi beberapa data yakni produksi, tenaga kerja, jam kerja, mesin, dan pemakaian daya listrik pada bulan Maret 2015 s.d. bulan Maret 2016. Hasil penelitian yang dilakukan mengenai analisis produktivitas pada periode bulan Maret 2015 s.d. bulan Maret 2016 menunjukkan adanya penurunan performa yang diindikasikan oleh beberapa rasio bernilai rendah. Pengelompokkan katagori penilaian nilai rasio menggunakan metode Traffic Light System. Pemanfaatan metode OMAX ini dilakukan sebagai analisis peningkatan produktivitas bagi PT XYZ dalam meningkatkan produktivitas sumber daya terkait secara berkelanjutan
Göç, Göçmen Politikaları ve Türkiye’de İşgücü Piyasalarında Prekaryalaşma
Authors: ÖRMECİ GÜNEY Gülay , CENGİZ Sibel
Published: February 2023

Bu çalışmada Türkiye’deki yabancı göçü ve göçmen politikaları ile işgücü piyasalarında prekarya olarak adlandırılan güvencesizlik ve ilgili kavramlar ele alınmıştır. Çalışmanın amacı bu kavramlar çerçevesinde Suriyeli ve Afgan göçmenler hakkında güncel verilerle durum tespiti yapmak ve göçmenlerin işgücü piyasalarının yeni prekaryası olup olmadığını sorgulamaktır. Özellikle son on yılda göçmen sayısındaki artışın işgücü piyasalarına yansıması ile ilgili güncel çalışmalar, raporlar ve veriler ile durum tespiti yapılmıştır. Suriyeli ve Afgan göçmenlerin Türkiye işgücü piyasalarının neden yeni prekaryası olduğu tümden gelimci bir betimleme çalışması yoluyla ortaya konulmuştur. Türkiye ekseninde göç ve göçmen politikaları ve piyasada bugün gelinen noktada, ülkenin yeni prekaryasının Suriyeli ve Afgan göçmenlerden oluştuğu sonucuna varılmış ve gerekçeleri anlatılmıştır. Çalışma sonunda Türkiye’de son yıllarda yurtdışından gelenlerin sayısındaki artışın, işgücü piyasalarında yapısal değişimleri gerekli kıldığı, yapısal değişimlerin göçmen politikaları üzerinde etkili olduğu, işgücü piyasalarında küresel anlamda; güvencesizlik, kayıt dışılık, ücret düşüklüğü ve esneklik artışı yaşandığı, göçmenlerin işgücü piyasalarında varlık göstermeye başlaması ile birlikte işgücü piyasalarında varlığını koruyan yapısal sorunların biraz daha derinleştiği tespit edilmiştir.
Principais causas da queda em idosos: um despertar para a prevenção
Authors: Oliveira Sheyla Macêdo Ribeiro de , Morais Alanna Michely Batista de , Sousa Milena Nunes Alves de
Published: February 2023

Objetivo: Realizar uma revisão integrativa a respeito da queda em idosos com foco na prevenção. Métodos: Foi desenvolvida a coleta de dados no meio eletrônico, a partir da busca de artigos científicos que demonstrasse relevância para compor os resultados. Utilizou-se plataformas científicas a exemplo do Scientific Electronic Library Online (SCIELO), Lilacs e PubMed. Selecionou-se artigos publicados em português e inglês, publicados entre os anos de 2017 e 2022. Resultados: A queda no idoso é um ato não intencional que causa situações adversas na qualidade de vida, sendo a residência do mesmo o ambiente mais propicio para essa a queda. A queda pode ser ocasionada pelo organismo envelhecido, onde a redução na proporção de fibras musculares anaeróbicas de contração rápida. Considerações finais: Como forma de prevenir esse efeito negativo na vida do idoso, os estudos apontam que o mesmo deve realizar atividades físicas que acoplem força, equilíbrio, coordenação e flexibilidade realizados, pelo menos três vezes por semana.
CONTINUATION OF THE ARCHAEOLOGICAL RESEARCH OF THE GRAND CHAMBER OF THE PALACE COMPLEX OF THE ALEXANDROVSKAYA SLOBODA IN 2019
Authors: Турова Е.А.
Published: February 2023

Археологическими исследованиями Древнерусской экспедицией Государственного Эрмитажа на территории юго-западного участка соборной площади древней Александровской Слободы в 2019 г. раскрыты остатки двух каменных палат великокняжеской и царской резиденции, датируемых началом XVI в и 1570-ми гг. Впервые археологически исследованы остатки парадных сооружений, которые упомянуты в чинах и разрядах свадеб Ивана Грозного и царевича Ивана Ивановича и могут быть соотнесены с изображениями на гравюрах И. Т. де Бри из издания записок Я. Ульфельда 1578 г.

Archaeological research by the old Russian state Hermitage expedition on the territory of the South-Western section of the Cathedral square of the ancient Alexander Sloboda in 2019 revealed the remains of two stone chambers of the Grand Ducal and Royal residence, Dating from the beginning of the XVI century and the 1570s. For the first time, the remains of ceremonial structures that are mentioned in the ranks and categories of the weddings of Ivan the Terrible and Tsarevich Ivan Ivanovich and can be correlated with the images on engravings by I. T. de Brie from the 1578 edition of the book by Jacob Ulfeld have been studied archaeologically.
GLASSWARE FROM THE EXCAVATIONS IN MUROM
Authors: Данилов О.В. , Абрамов Д.В.
Published: February 2023

Статья посвящена стеклянным сосудам из раскопок на Богатыревой горе в городе Муроме Владимирской области в 2017 г. В коллекции индивидуальных находок, собранной в ходе этих раскопок, выделяются две группы фрагментов стеклянной посуды. Первая группа состоит из фрагментов бокалов XII-XIII вв. Вторая группа объединяет фрагменты сосудов XVI-XVII вв. Импортные сосуды древнерусского периода представлены фрагментами изготовленных на Ближнем Востоке бокалов с орнаментом из накладных тонких фиолетовых стеклянных нитей и с росписью золотом и эмалью, изготовленных в ранний период бытования таких изделий. Среди позднесредневековых находок выделяются фрагменты сосуда с белой и синей филигранью, выполненного в технике «Fagon de venise»

The article is devoted to glass vessels from the excavations on Bogatyryova Mountain in the Murom (Vladimir region, Russia) in 2017. Two groups of glassware fragments stand out in the collection of finds collected during these excavations. The first group consists of fragments of goblets or beakers of the XII-XIII centuries. The second group combines fragments of vessels of the XVI-XVII centuries. Imported vessels of the Old Russian period are represented by fragments of Middle East goblets or beakers with an ornament of thin violet glass threads and with painting with gold and enamel, which were made in the early period of the existence of such products. Fragments of the vessel with white and blue filigree stand out among the late medieval finds. The vessel was made with using the “Fagon de venise” technique.
NEW EVIDENCES FOR MEDIAVAL METAL PRODUCTION FROM SUZDAL
Authors: Рузанова С. А. , Баранов Н. А.
Published: February 2023

В данной статье рассматривается опыт исследования шлаков и фрагментов горнов, найденных в ходе охранных археологических работ в г. Суздале на территории посада XII-XIII вв. В работе рассмотрены общие особенности подобного исследования, от морфологического до химического и микроструктурного анализа. Использование этих методов в данном случае позволило исследователям сделать вывод об одновременном (или близком во времени) существовании на указанной территории двух металлообрабатывающих производств с разным характером деятельности: мастерской, специализированной на обработке цветных металлов, и кузнечной мастерской. Полученные результаты свидетельствуют об информативности изучения шлаков как дополнительного источника при выявлении характера древних производств, связанных с металлообработкой.

This paper describes the scientific investigation of the medieval metal production residues from Suzdal. Different metallurgical materials were identified as smithing hearth bottoms or fragments of vitrified hearth lining. The samples were studied using chemical and microstructural analyses. The results of the analyses indicate that the residues originated from two different metal production processes.
Extraction, Physicochemical Characterization and Pharmacological Evaluation of Alginate from a Mediterranean Species of Brown Algae Dictyopteris membranaceae
Authors:   Department of Drug Development, Faculty of pharmacy, University of Monastir, Tunisia, R Ayadi
Published: February 2023

Brown seaweeds have attracted the attention of research. Alginates, one of the components of brown seaweed, are the subject of our study. In this work, we present the extraction, the physico-chemical characterization and the pharmacological evaluation of alginate from the brown seaweed Dictyopteris membranaceae. The extraction of alginates from brown seaweed was conducted using Rioux et al. method with few modifications. The characterization of alginates was then preceded by infra-red spectroscopy. The content of different components was determined using Ultraviolet-visible spectroscopy. Molecular properties were determined using size exclusion chromatography. The results of our study showed that the yield of extraction of alginate from Dictyopteris membranacea is 7% of dry weight. Protein, total sugar and alginic acid content were determined using colorimetric assays. The results are comparable to those reported in literature. The infra-red spectrum confirmed the nature of our extract. The molecular weight is 77823 Daltons. Additionally, our extract presented a higher gastroprotective activity at 200mg/Kg than sucralfate administered at the same dose. Our results suggest that alginate from Dictyopteris membranaceae could be used as a gastroprotective agent.
Large Decrease in Melting Point of Benzoquinones via High-n Eutectic Mixing Predicted by a Regular Solution Model
Authors: Baclig Antonio , Ganapathi Devi , Ng Victoria , Penn Emily , Saathoff Jonathan , Chueh William
Published: February 2023

Decreasing the melting point (Tm) of a mixture is of interest in cryopreservatives, molten salts, and battery electrolytes. One general strategy to decrease Tm, exemplified by deep eutectic solvents, is to mix components with favorable (negative) enthalpic interactions. We demonstrate a complementary strategy to decrease Tm by mixing many components with neutral or slightly positive enthalpic interactions, using the number of components (n) to increase the entropy of mixing and decrease Tm. In theory, under certain conditions this approach could achieve an arbitrarily low Tm. Furthermore, if the components are small redox-active molecules, such as the benzoquinones studied here, this approach could lead to high energy density flow battery electrolytes. Finding the eutectic composition of a high-n mixture can be challenging due to the large compositional space, yet is essential for ensuring the existence of a purely liquid phase. We reformulate and apply fundamental thermodynamic equations to describe high-n eutectic mixtures of small redox-active molecules (benzoquinones and hydroquinones). We illustrate a novel application of this theory by tuning the entropy of melting, rather than the enthalpy, in systems highly relevant to energy storage. We demonstrate with differential scanning calorimetry measurements that 1,4-benzoquinone derivatives exhibit eutectic mixing that decreases their Tm, despite slightly positive enthalpies of mixing (0-5 kJ/mol). By rigorously investigating all 21 binary mixtures of a set of seven 1,4-benzoquinone derivatives with alkyl substituents (Tm's between 44-120 °C), we find that the eutectic melting point of a mixture of all seven achieves a large decrease in Tm to -6 °C. We further determine that the regular solution model shows improvement over an ideal solution model in predicting the eutectic properties for this newly investigated type of mixture composed of many small redox-active organic molecules.
Assessing the effect of protein corona formation in the process of EV surface engineering
Authors: Musicò Angelo , Zenatelli Rossella , Romano Miriam , Zendrini Andrea , Alacqua Silvia , Tassoni Selene , Paolini Lucia , Urbinati Chiara , Rusnati Marco , Bergese Paolo , Pomarico Giuseppe , RADEGHIERI Annalisa
Published: February 2023

To be profitably exploited in medicine as drug delivery carriers, nanosized systems should be endowed with essential properties, including high biocompatibility, stealth ability to escape the immune system, prolonged circulation lifetime, and targeting abilities towards the pathological tissues. Currently, the choice of biogenic nanoparticles as Extracellular Vesicles (EVs) represents the most promising strategy to deal with clearance issues. EV targeting properties and pharmacokinetics could be augmented by surface engineering methods by inserting specific target ligands, including antibodies or small peptides. Biorthogonal chemistry allows for the formation of a stable covalent bond among these moieties and EV surface, ensuring the maintenance of biomolecule’s reactivity. As for synthetic nanoparticle counterparts, it has recently been acknowledged proteins might physically adsorb on the EV surface in biofluids, forming a protein corona (PC), thus modifying EV biological identity. This phenomenon cannot be overlooked when investigating the properties and behavior of nanosized systems in biological media. In this work, we explored the possibility to engineer the EV surface with a modified antibody (Cetuximab, CTX) by both chemisorption (via click chemistry reaction) and physisorption (forming a protein corona) mechanisms. We found that both mechanisms are suitable to engineer the EV surface and, at the molecular level, SPR analysis showed that EV formulations functionalized by CTX, through its physisorption or chemisorption presented a comparable affinity for EGFR. However, at the cellular level, the improved stability for CTX-EV prepared by click chemistry strategies confers superior binding and uptake ability toward target cells. These results highlight for the first time the EV-PC formation during surface engineering processes and suggest its functional role, which should be carefully estimated in EV-based drug delivery system development due to the lower stability of the EV-PC compared to the covalent chemical binding between EV and CTX.
Role of Intermittency on the Effectiveness of Methane Emissions Detection at Oil and Gas Facilities: Comparative Assessment of Optical Gas Imaging and Site-wide Surveys
Authors: Strayer Alan , Ravikumar Arvind
Published: February 2023

Intermittent emission events are a significant source of methane emissions from oil and gas operations. New technologies such as site-wide aerial surveys promise more effective detection of intermittent emission events compared to conventional optical gas imaging (OGI) surveys. In this work, we present case studies to assess role of intermittent emission events on the emissions reduction equivalence between conventional OGI-based surveys and site-wide screening surveys with new technologies. We find that the equivalence condition between OGI-based surveys and site-wide screening is robust against different assumptions about the duration of large emitters. As duration of large emitters decrease, monthly site-wide screening surveys are more effective at detecting large emitters compared to quarterly OGI monitoring. However, the contribution of large emitters to total emissions also decreases, which reduces the impact of the higher detection effectiveness of site-wide surveys. In addition, annual OGI survey as part of site-wide screening strategy is more critical when the detection threshold of the screening technology is greater than 10 kg/h or higher as the screening survey does not detect below detection threshold emissions.
Influence of Mg2+ Distribution on the Stability of Folded States of the Twister Ribozyme Revealed using Grand Canonical Monte Carlo and Generative Deep Learning Enhanced Sampling
Authors: Sengul Mert , MacKerell Alexander
Published: February 2023

Metal ions, particularly magnesium ions (Mg2+), play a role in stabilizing the tertiary structures of RNA molecules. Theoretical models and experimental techniques show that metal ions can change RNA dynamics and how it transitions through different stages of folding. However, the specific ways in which metal ions contribute to the formation and stabilization of RNA's tertiary structure are not fully understood at the atomic level. Here, we combined oscillating excess chemical potential Grand Canonical Monte Carlo (GCMC) and metadynamics to bias towards the sampling of unfolded states using reaction coordinates generated by machine learning allowing for examination of Mg2+-RNA interactions that contribute to stabilizing folded states of the pseudoknot found in the Twister ribozyme. GCMC is used to sample diverse ion distributions around the RNA with deep learning applied to iteratively generate system-specific reaction coordinates to maximize conformational sampling during metadynamics simulations. Results from 6 s simulations performed on 9 individual systems indicate that Mg2+ ions play a crucial role in stabilizing the 3D structure of the RNA by stabilizing specific interactions of phosphate groups or phosphate groups and bases of neighboring nucleotides. While many phosphates are accessible to interactions with Mg2+ it is observed that multiple, specific interactions are required to sample conformations close to the folded state; coordination of Mg2+ at individual specific sites facilitates sampling of folded conformations though unfolding ultimately occurs. It is only when multiple specific interactions occur, including the presence of specific inner shell cation interactions linking two nucleotides, that conformations close to the folded state are stable. While many of the identified Mg2+ interactions are observed in the X-ray crystal structure of Twister, the present study suggests two new Mg2+ ion sites in the Twister ribozyme that contribute to stabilization. In addition, specific interactions with Mg2+ are observed that destabilize the local RNA structure, a process that may facilitate the folding of RNA into its correct structure.