bluuebunny/crossref_metadata_2025 huggingface dataset:
Hubungan Ibu Hamil Kekurangan Energi Kronik Dengan Kelahiran Bayi Berat Badan Lahir Rendah
Authors: Dwi Handayani Paramita Benny  , Idah Ayu Wulandari  , Sri Ariani Ni Komang , Ni Wayan Sri Rahayuni  , Ni Ketut Noriani
Published: July 2024

Pregnant women who have less nutritional intake adequately during pregnancy have the potential to experience chronic energy deficiency (CED) and tend to give birth to babies with low birth weight (LBW). One of the indicators used to determine chronic energy deficiency in mothers is upper arm circumference <23.5cm. The impact of LBW on children's growth is the occurrence of stunting. The purpose of this study was to determine the correlation between chronic energy deficiency and low birth weight babies at the Public Health Center Kambaniru, East Sumba. This study employed quantitative analysis with a cross-sectional approach. The sample was 29 respondents recruited from medical record data of pregnant women who gave birth to LBW babies. Data were analyzed using the Spearman's Rho correlation technique test. Findings indicated that the majority of 19 respondents (65.5%) with CED gave birth to children with LBW conditions, while 10 respondents (34.5%) without CED also gave birth to LBW babies. The Spearman's Rho test results indicated a significant positive correlation between mothers with CED and LBW babies. The lower the upper arm circumference of a pregnant woman, the higher the risk of giving birth to a LBW baby. It is expected that pregnant women will always carry out regular health checks during pregnancy and consume sufficient nutritious food.
Pengaruh Pendidikan Kesehatan Melalui Media Booklet Terhadap Pengetahuan dan Sikap PPIA Pada Ibu Hamil
Authors: Anis Nikmatul Nikmah  , Meirna Eka Fitriasnani  , Lindha Sri Kusumawati  , Fithri Rifatul Himmah
Published: July 2024

PPIA (Prevention of HIV-Transmission from Mother to Child) is one of the efforts to control HIV-AIDS and STIs in pregnant women. Data from Kediri City in 2023, from the target of 263 pregnant women, 248 people checked PPIA and there was 1 pregnant woman who was HIV positive. The low coverage of pregnant women is forced to do an examination because this is a mandatory program that must be done. The purpose of this study was to determine the Effect of Health Education through Booklet Media on PPIA Knowledge and Attitudes in Pregnant Women. This research method is a pre-experimental, one group pretest-postest design design. Population of all pregnant women who visited the health center with the number of invinite. The research sample was 30 respondents. Sampling technique with Acidental Sampling. Research location at Puskemas Ngletih Kediri City in January 2024 Data collection through questionnaires to obtain primary data. Test research analysis with Wilcoxon test. The results showed that after being counseled, most of the knowledge was sufficient by 16 respondents (53.3%) and most of the attitudes were positive by 22 respondents (73.3%). Based on the Wilcoxon test on knowledge obtained PValue 0.000<α 0.05) while in the attitude P Value 0.012<α 0.05 which means H0 is rejected and H1 is accepted. From the results of the study, it was concluded that there is an influence of health education through booklet media on the knowledge and attitudes of PPIA in pregnant women. Health workers are expected to always strive to provide socialization and motivation to pregnant women so that the knowledge and attitudes of pregnant women about PPIA prevention will increase.
Cost-effectiveness analysis of mirogabalin in treatment of diabetic peripheral neuropathic pain and post-herpetic neuralgia in China
Authors: Wu Yao , Tao Libo , Liu Chang , Wang Fangxu , Sun Shuang
Published: July 2024

Objective: To evaluate the cost-effectiveness of mirogabalin in treatment of Chinese patients with DPNP or PHN, and to discuss
its reasonable pricing strategy.
Methods: A cost-effectiveness analysis was performed by constructing a three-state Markov model (mild, moderate, and
severe pain) to compare mirogabalin with placebo and pregabalin for DPNP or PHN patients from Chinese healthcare system
perspective. The efficacy parameters were derived from randomized clinical trials (RCTs) comparing mirogabalin with placebo in
the treatment of PHN or DPNP, as well as from network meta-analyses comparing mirogabalin/pregabalin with placebo RCTs.
The health utility values were obtained from published literatures. Cost parameters contained cost of pregabalin, supportive
care, and other medical resource utilization, were sourced from both published literature and public price database. Sensitivity
analysis was conducted on key parameters to verify the stability of the results.
Results: With one-year time horizon, for PHN, the incremental quality-adjusted life years (ΔQALYs) of mirogabalin compared with
placebo and pregabalin were 0.048 and 0.025 respectively; For DPNP, the ΔQALYs of mirogabalin compared with placebo and
pregabalin were 0.021 and 0.017 respectively. Using the national volume-based procurement price of pregabalin as a reference,
with 1 and 3 times the per capita GDP in China (￥89,358, 2023) as thresholds, the daily cost of mirogabalin was found to be
cost-effectiveness when it was within 1.64 times (DPNP) or 2.07 times (PHN), 2.47 times (DPNP) or 3.46 times (PHN) of the
daily cost of pregabalin. One-way sensitivity showed that, utility values of mild and moderate pain, costs of mirogabalin had the
biggest influence on incremental cost-effectiveness ratio.
Conclusion: As a novel calcium channel modulator, the cost-effectiveness of mirogabalin is greatly influenced by the reference
drug. When pricing in China, it is essential to select appropriate comparator drugs and their prices as references.
Key words: cost-effectiveness, mirogabalin, diabetic peripheral neuropathic pain, postherpetic neuralgia
Cost-effectiveness analysis of Trastuzumab Deruxtecan as second-line treatment for HER2- positive advanced breast cancer
Authors: Xiao Feiyi , Xiao Wudong , Li Xue , Li Rui , Zhao Kun
Published: July 2024

Objective: To analyze the cost effectiveness of trastuzumab detrastuzumab (T-Dxd) or trastuzumab emtezumab (T-DM1) in
patients with HER2-positive advanced breast cancer who were previously treated with trastuzumab and taxanes.
Methods: Based on the perspective of China’s health system, a partitioned survival model is constructed to simulate the direct
medical costs, life years and quality-adjusted life years of patients throughout their life cycle. The basic scenario set by the model
is: based on the data of the Asian-Pacific population in the DESTINY-Breast03 (DB03) phase III clinical trial, the experimental
group and the control group were given intravenous infusion of T-Dxd and T-DM1 at a frequency of every 3 weeks respectively
until the patients’ disease progressed. Clinical effect data and health utility values come from individual patient-level data of the
Asia-Pacific population in the DB03 Phase III clinical trial. Direct medical costs include drug costs, follow-up treatment costs,
adverse event treatment costs, medical service costs, examination and testing costs, and hospice care costs.
Results: In the basic scenario, T-Dxd can reduce the risk of disease progression in patients, and compared with T-DM1, patients’
life years and quality-adjusted life years are improved. Calculated based on China’s per capita GDP in 2022 (85,698 yuan),
the incremental cost-effectiveness ratio (ICER) in the case of donated drugs is within the threshold of 2 times per capita GDP.
Conclusion: Trastuzumab Deruxtecan (T-Dxd) can extend the life years and improve the quality of life of patients with indications.
Under the condition of drug donation, the use of T-Dxd has a comparative advantage of cost-effectiveness.
Key words: cost-effectiveness analysis, trastuzumab deruxtecan, breast cancer, antibody-drug conjugate, economy
Establishment of a predictive model for antidepressant efficacy based on machine learning
Authors: Liu Yiyao , Ni Huitong , Zhi Teng , Zhao Ziqi , Zeng Xiaoxi , Hu Ming , Wu Zhiang
Published: July 2024

Objective: Establishing a model can accurately predict the depressive patient’s response to different drugs, thereby providing
personalized treatment plans to improve treatment outcomes.
Methods: Depressive patients who have taken Paroxetine hydrochloride or Venlafaxine hydrochloride or Agomelatine at a
hospital in Sichuan Province are the subjects. By analyzing their medical records, medication histories, and basic information,
an predictive model is constructed to predict the efficacy of antidepressant medications based on eXtreme Gradient Boosting.
Results: For the prediction model of Paroxetine hydrochloride, 52 variables selected by the model were used to construct an
efficient predictive model. In the training set, the model achieved an AUC value of 0.6354 and a K-S value of 0.1944, indicating
good performance in correctly classifying positive and negative samples and distinguishing different predictive probability
thresholds. In the validation set, the AUC was 0.6065, and K-S was 0.1847, confirming the model’s effectiveness on new data.
Compared to actual clinical data, the efficacy of sertraline hydrochloride was approximately 61.9%. The model’s predictions
aligned well with real-world data, reinforcing its reliability and practicality. As for venlafaxine hydrochloride, the model achieved
an AUC of 0.5745 and K-S of 0.149 on the training set, while the validation set showed an AUC of 0.5298 and K-S of 0.0597.
These results suggest that the model’s performance in predicting venlafaxine hydrochloride is mediocre. Comparing with
clinical data, the efficacy of venlafaxine hydrochloride was approximately 68.9%, indicating a discrepancy between the model’s
predictions and actual outcomes, possibly due to the uneven distribution of the training set samples. As for agomelatine, due
to the insufficient number of agomelatine samples collected at the sample hospital (less than 200), an effective predictive model
could not be established.
Conclusion: In clinical practice, doctors can make more informed treatment decisions and achieve personalized antidepressant
therapy with the assistance of this model.
Key words: predictive model, machine learning, antidepressant efficacy, depressive patients, clinical practice
Optimizing covariate selection and results inference in anchored matched adjusted indirect comparison method
Authors: Rui Mingjun , Li Hongchao , Wang Yingcheng
Published: July 2024

Indirect comparison methods become particularly prominent in pharmacoeconomic evaluations. This study delves into the
anchored matched adjusted indirect comparison (MAIC) method, spotlighting the challenges of selecting appropriate covariates
and distinguishing between predictive and prognostic factors. In addition, our research bridges the gap of MAIC results application
inference, enhancing the methodological rigor and applicability of MAIC analyses. Through theoretical exploration and a detailed
case study of toripalimab and pembrolizumab in the neoadjuvant treatment of NSCLC, we demonstrate the significant impact of
covariate selection on the outcomes of pharmacoeconomic evaluations. Analyzing the individual patient data by using statistical
methods alone is insufficient to identify all potential prognostic factors. Instead, a combination of previously published related
research and expert consultations is necessary. The individual patient data network meta-analysis should be employed if the
shared effect modifier assumption is not met to make the MAIC results be inferred for the real-world decision-making population.
Key words: matched adjusted indirect comparison, covariate selection, results inference
Pharmacoeconomic studies on biologic agents for ankylosing spondylitis: A systematic review
Authors: Shi Jiaqi , Zhao Ziqi , Zhou Wenxin , Hu Ming
Published: July 2024

Objective: This study aims to systematically review and assess the quality of published pharmacoeconomic studies on biologic
agents for ankylosing spondylitis conducted both domestically and internationally.
Methods: PubMed, Embase, and the Cochrane Library databases were searched using English keywords such as “ankylosing
spondylitis” and “pharmacoeconomics.” Chinese databases, including China National Knowledge Infrastructure (CNKI) and
Wanfang Database, were searched using Chinese keywords such as “ankylosing spondylitis”, “cost” and “effectiveness”. The
search was conducted from the inception of the databases until February 2023. The quality of the included studies was assessed
using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS 2022) and the Quality of Health Economics
Studies Instrument (QHES). Two researchers extracted data from the included studies, and descriptive analysis was performed
to summarize the characteristics of the included studies.
Results: A total of 24 English-language studies were included in the review. The included studies were published between 2004
and 2020, with 19 studies classified as high-quality and 5 studies as “general quality studies.” Furthermore, 18 studies (75%) were
model-based pharmacoeconomic evaluations, including Markov models, mathematical models, and discrete event simulation
models. In terms of economic evaluations, Tumour necrosis factor (TNF) inhibitors and IL-17 inhibitors were found to be more
cost-effective compared to traditional nonsteroidal anti-inflammatory drug (NSAIDs) treatment. Factors such as the BASDAI 50
response rate and disease-related costs had varying degrees of impact on the incremental cost-effectiveness analysis results.
Conclusion: The overall results indicate that, in the short-term treatment scenario, biologic agents are not cost-effective
compared to traditional treatment options, but in the long-term treatment scenario, biologic agent treatment becomes more
cost-effective. The most cost-effective intervention measures varied among different studies comparing different biologic agents.
Key words: ankylosing spondylitis, biologicals, pharmacoeconomic evaluation, systematic review, TNFis inhibitors, IL-17 inhibitor
The parameter variation of one-way sensitivity analysis in economic evaluation: Global systematic review
Authors: Li Pingping , Liu Xiangyu , Jiang Chen , Yang Zeying , Tian Yihe , Zhao Min , Yan Hualing , Li Hongchao
Published: July 2024

Objective: One-way sensitivity analysis (OSA) plays a crucial role in economic evaluations (EEs), yet knowledge about parameter
range and research practices is limited. Understanding these patterns is essential for reliable healthcare decision-making. This
study aims to describe OSA patterns in EEs, providing insights into parameter ranges and good research practices.
Methods: Systematic searches on PubMed, MEDLINE, Embase, and ScienceDirect were conducted for model-based EEs
published in English (2021-2023). Neoplasm-related articles were prioritized due to their abundance. Screening, data extraction,
and quality assessment were performed by two independent reviewers. Study characteristics, OSA methods, and OSA result
diagrams were collected. Study quality was assessed using the Criteria for Health Economic Quality Evaluation (CHEQUE) tool.
Results: Among 7,885 records, 362 articles were extracted. Economic parameters such as price per unit, packaging cost,
and number of healthcare utilization were commonly varied in OSA (94%). Efficacy parameters (84%), utility parameters (79%),
and safety parameters related to adverse event and complication (54%) were also frequently varied. Only 67% of the articles
described parameter variation methods, 73% listed parameter change ranges, and only 34% explicitly stated the rationale
behind parameter variations. A taxonomy of OSA range types was developed, including practices such as literature review,
confidence intervals, practical context, clinical opinion, extreme values, percentage/distance variations, guideline provisions,
author assumptions, unknown ranges/types, uncertain variations, and others. Good practices for OSA were recommended.
Tornado diagrams were the most common OSA result plots (88%), accompanied by table, curve, and line chart. Method quality
scored 13 out of 18 points, while reporting quality scored 12 out of 17 points.
Conclusion: This systematic review revealed unsatisfactory quality in the methods and reporting of OSA in neoplasm EEs.
Recommendations are provided for parameter variation methods, ranges, references, and chart presentation for future OSA
studies.
Key words: parameter variation, one-way sensitivity, systematic review, economic evaluation
Niñas y niños investigadores. Cuestionando la investigación académica
Authors: Martínez Muñoz Marta , Liebel Manfred
Published: July 2024

Manfred Liebel y Marta Martínez MuñozResumenLa investigación de la infancia, incluso cuando se concibe como investigación participativa, se mueve dentro de un corsé académico en el que el poder está desigualmente distribuido y los intereses y perspectivas de los niños sólo se expresan de forma limitada. Los adultos investigadores que quieren hacer justicia a estos intereses y perspectivas tienen que asumir el riesgo de no sólo entender a los niños como parte de un proyecto de investigación predefinido, sino de reconocerlos como investigadores por derecho propio y, si es necesario, apoyarlos en ello. En este ensayo se analizan las dificultades y desafíos que ello implica y se dan ejemplos de las oportunidades especiales de conocimiento que ofrece la investigación dirigida por niños y las formas en que éstos pueden beneficiarse de ella.Palabras claveInvestigación de la infancia; investigación participativa; adultos como co-investigadores; investigación dirigida por niños; beneficios para niños ResumoA investigação infantil, mesmo quando concebida como investigação participativa, move-se dentro de um espartilho académico em que o poder é distribuído de forma desigual e os interesses e perspectivas das crianças só são expressos de forma limitada. Os adultos investigadores que querem fazer justiça a estes interesses e perspectivas têm de correr o risco de não só compreender as crianças como parte de um projecto de investigação pré-definido, mas também de as reconhecer como investigadoras por direito próprio e, se necessário, de as apoiar nesse sentido. O documento discute as dificuldades e os desafios envolvidos e dá exemplos das oportunidades especiais de conhecimento oferecidas pela investigação liderada por crianças e das formas como as crianças podem beneficiar dela.Palavras-chaveInvestigação infantil; investigação participativa; adultos como co-investigadores; investigação conduzida por crianças; benefícios para as criançasAbstractChildhood research, even when conceived as participatory research, moves within an academic corset in which power is unequally distributed and children’s interests and perspectives are only expressed to a limited extent. Researching adults who want to do justice to these interests and perspectives have to take the risk of not only understanding children as part of a predefined research project, but of recognizing them as researchers in their own right and, if necessary, supporting them in this. The paper discusses the difficulties and challenges involved and gives examples of the special knowledge opportunities offered by child-led research and the ways in which children can benefit from it.KeywordsChildhood research; participatory research; adults as co-researchers; child-led research; benefits to children
La inclusión de la perspectiva generacional en salud. Co-construir salud con las niñeces en territorio.
Authors: Apaz Soledad
Published: July 2024

El objetivo de este artículo es reflexionar sobre la importancia de incluir la perspectiva generacional, en el análisis y las prácticas en salud, para comprender cómo operar en intersección con otros marcadores sociales como la clase social, el género, la razón, la etnia, la funcionalidad normativa, la determinación de los procedimientos de salud. Y también pensar posibilidades de transformación de nuestras prácticas como trabajadorxs de salud desde una perspectiva, feminista y de co-protagonismo de las infancias/adolescencias para co-construir salud con ellxs como protagonistas protagonistas de esos procesos.
Vozes das crianças em contexto de violência testemunhal: desafios para uma escuta ética
Authors: Gomes Ana Paula Pereira , Finco Daniela
Published: July 2024

Este artigo trata da violência doméstica conjugal que permeia a vida das crianças e mulheres. Aborda a problemática das expressões das crianças pequenas em contexto de violência testemunhal, apontando os desafios de uma escuta ética e acolhedora. Surgiu de uma pesquisa de doutorado que entrevistou 7 profissionais da rede de apoio contra violência e de escolas de Educação Infantil de São Paulo. Tem como referenciais teóricos os Estudos Sociais da Infância, que evidenciam a participação da criança na sociedade como sujeito de direitos, e os Estudos Feministas e de Gênero, que localizam a criança e a mulher na sociedade patriarcal. Os resultados problematizam os valores atribuídos às vozes dessas crianças, com o problema da dupla violência exercida contra elas: a violência testemunhal e a condição de invisibilidade, trazendo subsídios para pensar condições e modos de intervir para garantir a proteção e o direito das crianças à uma vida sem violência.
Construyendo campos de interlocución: un taller de antropología como dispositivo metodológico de investigación con niño/as
Authors: Piñeyro Leandro
Published: July 2024

Realizar investigaciones con niños y niñas tiene implícita la implicancia de la relación asimétrica entre la niñez y la adultez. A la hora de plantear esquemas metodológicos hay que problematizar esta relación de poder. En este artículo reflexiono sobreel pensar-sentir-accionar de las relaciones de poder existente en un grupo escolar. Describoun taller de antropología con niños y niñas realizado en una escuela de la ciudad de Montevideo que se tornó un dispositivo metodológico de investigaciones. A partir de este taller pude observar que niños y niñas tienen una compleja visión de las relaciones de poder y una concepción sumamente dinámica del dispositivo de alteridad. Concepción que los ubica en un rol activo, protagónico a la hora de habitar una relación asimétrica. Hecho que debe ser tomado en cuenta a la hora de construir las reflexionarsobre los espacios habitados por las infancias.
Voces de niños y niñas sobre el COVID 19. Avances, obstáculos y desafíos de un estudio argentino
Authors: Querejeta Maira , Laguens Ana , Romanazzi María Justina
Published: July 2024

Este trabajo aborda la inclusión de las perspectivas de niños y niñas sobre la pandemia de COVID-19 desde una posición crítica que destaca la importancia de considerar la agencia social infantil y evitar visiones simplistas al interpretar sus voces. El estudio se enmarca en una investigación interdisciplinaria más amplia que buscó comprender la experiencia de niños y adolescentes durante la pandemia recurriendo a distintas fuentes. Para este estudio, se convocó a niños de diferentes niveles educativos a expresar sus pensamientos y emociones a través de dibujos, relatos y videos. Las producciones artísticas reflejaron temas recurrentes como el virus, las medidas preventivas y los cambios en la vida cotidiana. Aunque la pandemia presentó desafíos en la interacción con los niños, las producciones proporcionaron una visión de sus percepciones en un contexto extraordinario. Las conclusiones se basaron en las producciones, con reconocimiento de los desafíos y obstáculos inherentes a la situación pandémica, así como específicos de la investigación con niños.
Das vozes fetichizadas ao diálogo intergeracional: desafios da pesquisa com crianças na América Latina
Authors: Szulc Andrea , Shabel Paülah
Published: July 2024

A investigação social sobre a infância desenvolveu-se vigorosamente nas últimas décadas na América Latina e registou progressos no reconhecimento, na visibilidade e na análise das formas como as crianças participam ativamente e dão sentido à vida social em cada um dos seus contextos. No entanto, “dar voz” às crianças tornou-se um imperativo que muitas vezes bloqueia a reflexão mais profunda sobre a complexidade que isso implica, produzindo uma fetichização que separa essas vozes dos seus contextos e das estruturas sociais de desigualdade em que se inserem. Aqui desdobramos algumas chaves conceituais para aprofundar o debate sobre essas vozes a partir das contribuições da antropologia, epistemologia, feminismos, teorias decoloniais e queer/cuir, que se unem em uma análise urgente diante do avanço das direitas regionais. Por fim, apresentamos brevemente os artigos que compõem a seção temática.
La otredad en la clase de matemáticas: experiencias didácticas matemáticas interculturales (EDMI) para aulas inclusivas
Authors: Peña-Rincón Pilar , Guerrero Patricia
Published: July 2024

Este artículo reflexiona sobre cuestionar la normalidad y diferencia en las clases de matemáticas, ya que estas ideas han generado exclusiones. Se presenta una investigación que utilizó una metodología cualitativa y colaborativa, incorporando matemáticas no hegemónicas mediante las Experiencias Didácticas Matemáticas Interculturales (EDMI). Se investigaron las influencias de esta experiencia intercultural en las creencias matemáticas docentes. Los resultados muestran cómo esta aproximación permite un cambio en la enseñanza de las matemáticas y en la forma en que vemos a los demás en el aula. Se propone la utilización de las EDMI para abordar la otredad en la formación docente y en el aula.
Probiotics to enhance animal production performance and meat quality: A review
Authors: Mia N , Alam AMMN , Rahman MM , Ali MS , Hashem MA
Published: July 2024

The utilization of probiotics in animal husbandry has garnered significant attention as a natural and effective strategy to enhance production performance and meat quality. This review synthesizes current research on the impact of probiotics on various livestock, including poultry, swine, and cattle. Probiotics, which are live microorganisms that confer health benefits to the host, have been shown to improve growth rates, feed conversion ratios, and overall health status of animals. Furthermore, they contribute to enhanced meat quality by influencing factors such as muscle composition, fat content, and oxidative stability. Mechanistically, probiotics exert their effects through modulation of gut microbiota, enhancement of nutrient absorption, and stimulation of the immune system. Studies also indicate a reduction in the incidence of diseases and a decrease in the need for antibiotic growth promoters, addressing concerns over antibiotic resistance. Despite promising results, variability in outcomes suggests that probiotic efficacy is influenced by factors such as strain specificity, dosage, and administration methods. Future research should focus on optimizing probiotic formulations and understanding the underlying mechanisms to maximize their benefits in animal production. This review highlights the potential of probiotics as a sustainable approach to improve animal performance and meat quality, contributing to more efficient and health-conscious animal agriculture.
Development of dietary fiber enriched sausage using rice bran
Authors: Sagar MSR , Habib M , Hashem MA , Azad MAK , Rahman MM , Ali MS
Published: July 2024

The study was conducted to evaluate the effect of de oiled rice bran as a source of dietary fiber on the sensory, physicochemical and biochemical properties of chicken sausages. For this purpose, sausages were prepared into 4 different groups. They were as follows: control; broiler breast meat sausage without rice bran, broiler breast meat sausage with 5% rice bran, broiler breast meat sausage with 10% rice bran, broiler breast meat sausage with 15% rice bran. All parameters were analyzed at 0, 14th and 28th days of storage period. The surface color (CIE L*, a*, b*) of sausages samples were measured using a Minolta Chroma meter at different storage period. DM, Ash, Crude fiber, EE and pH showed significantly different among the different sausage batters. All the parameters except pH was significantly lower in control group compare to different rice bran sausage batter group. During the analysis of sausages, all proximate parameters were significantly different among different sausage treatment groups. DM, Ash and EE contents were significantly higher in rice bran groups compare to control, while CP content and pH were significantly higher in control group. DM and CP% increased, while EE% and pH decreased with increasing the storage period. The lightness (L*) value was higher, while redness (a*) and yellowness (b*) values were lower in control sausage compare to rice bran group sausages. Free fatty acid, TBARS were significantly lower in control group compare to rice bran sausages group. Peroxide value and TBARS value increased with increasing the storage period. In sensory analysis, significantly lower color, off-flavor, juiciness and tenderness were found in broiler breast meat sausage without rice bran. Although color, off- flavor, juiciness and tenderness were not varied during sensory evaluation, flavor and overall acceptability significantly differ among the four treatments. Sensory evaluation indicated higher acceptability of sausage with 5% rice bran incorporated group compare to other rice bran incorporated sausage group.
Development of dietary fiber enriched chicken sausage using wheat bran
Authors: Shanaullah M , Habib M , Hashem MA , Azad MAK , Ali MS
Published: July 2024

The study was conducted to evaluate the effect of wheat bran on the sensory, physicochemical, and biochemical properties of chicken sausages. For this purpose, sausages were prepared into 4 different groups. Such as: control- broiler breast meat sausage without wheat bran, broiler breast meat sausage with the addition of 5% wheat bran, broiler breast meat sausage with the addition of 10% wheat bran, broiler breast meat sausage with the addition of 15% wheat bran. All parameters were analyzed at 0, 14 and 28 days of storage period. The surface color (CIE L*, a*, b*) of sausage samples were measured using a colorimetric meter at different storage period. The proximate composition, pH and cooking loss of different sausage batter were analyzed and significant differences were found in DM%, CF%, CP%, Ash%, EE%, and pH. The DM and CF% were significantly lower, while CP% was higher in control sausage batter. Highly significant (p<0.01) differences were found in DM, CP, CF, and Ash % in broiler breast meat sausages. DM, CF, and Ash% were significantly lower and CP% was higher in control sausage. Both CP and CF content were increased, but Ash and Fat content decreased with the increase of storage time. The storage period has significant effect (p<0.01) on different biochemical (POV and TBARS value) tests. POV and TBARS were increased with increasing the storage period. Lightness (L*) value showed significant (p<0.05) differences among different treatments and different storage period. Significantly (p<0.05) lower lightness and yellowness were found in broiler breast meat sausage without wheat bran. Again, redness and yellowness were decreased with increasing the storage period. In sensory analysis, flavor and overall acceptability were significantly higher in broiler breast meat sausages with 5% wheat bran (p<0.05). Taken together it may conclude that wheat bran at 5% level might be incorporated in broiler breast meat sausages with higher overall acceptability.
Uprising the effective estrus synchronization protocols with hormones in anestrus dairy and beef cows guided by rectal palpation
Authors: Nishi SA , Sarder MJU , Islam MA , Khaton R , Uddin J , Islam MH
Published: July 2024

The purpose of the study was to evaluate effective estrus synchronization protocols with hormones in anestrus cows guided by rectal palpation. About 200 dairy and beef cattle was selected at private and Govt. dairy farm of Rajshahi region from 1st July 2020 30th June, 2021. For this experiment animals were divided into 7 groups of different protocol and one control. Protocol-I, II and III was singly double and triple PGF2α injection Technique to inject PGF2α was @ 5ml Intramuscular at day 0, 11-14 and 9 & 11-14 days respectively 3 protocol and inseminated heated. Protocol -IV: GnRH–PGF2α–GnRH Technique to inject GnRH @ 5ml Intramuscular at day 0 and Check estrous and bred them. The second injection of PGF2α was administered 7 days after first injection similarly estrus and AI. The third injection of GnRH was administered 11-14 days after second injection similarly estrus and AI. Protocol -V: PGF2α–GnRH– PGF2α Technique to inject PGF2α @ 5ml Intramuscular at day 0 and the second injection of GnRH was administered 12 days after first injection. The third injection of PGF2α was administered 7 days after second injection similarly estrus and AI after 12-18 hours of fix times with GnRH injection. Protocol VI: GnRH– PGF2α Technique, to inject GnRH @ 5ml Intramuscular at day 0 and Check estrous and bred them. Second injection of PGF2α was administered 7 days after first injection similarly estrus and AI. Protocol -VII: hCG technique to inject hCG @ 1500 i.u. Intramuscularly at 0 day and observed up to 1 month. Protocol VIII: Control group (No treatment) (n=20), animal was observed for one month’s how many cows have shown estrus and check it after 120 day by rectal palpation. In results It showed that when hormonal treatment was given for induction of oestrus, higher (77.14%) proportion of cows showed oestrus compared to control counterpart (20.00%). The difference in the induction of oestrus in cows with different treatment protocol groups were 60%, 85%, 80%, 90% and 60% in PG, PG-PG, PG-PG-PG with fixed AI, PG-GnRH-PG with Fixed AI, GnRh-PG and hcG, respectively. It shows that the higher proportion of cows showed oestrus with hormonal treatment. Pregnancy rate of induction of estrous cycle by using different synchronization protocols were observed highest in 88.89% at PG-GnRH-PG fixed time AI technique and lowest 81.25% at GnRH-PG-GnRH fixed time AI protocol. Based on the experimental results. different treatment protocols compare in terms of their effectiveness in inducing estrus
Effect of freezing period on the quality of doe liver
Authors: Sharker BS , Mia N , Ali MH , Hashem MA , Rahman MM , Khan M
Published: July 2024

The current study examined how the quality of doe liver was affected by a freezing period at -20°C. Raw, fresh doe liver was collected for this purpose and split into three treatment groups. On day 0, day 60, and day 120, they received treatment as T1, T2, and T3, respectively. Liver samples were frozen at (-20°C) and wrapped in plastic bags. For each treatment, the parameter studied were biochemical properties (TBARS), proximate component (DM, CP, EE, and Ash), physicochemical properties (pH, cooking loss, and water holding capacity), sensory attributes (color, taste, juiciness, and tenderness), and microbiological qualities (TCC, TVC, and TYMC). The findings demonstrated that as the number of storage days increased across all treatments, color, taste, juiciness, and tenderness all reduced (p<0.05). DM content was significantly increase (p<0.05), whereas crude protein, ether extract and ash were decreased with the increase of days of storage. pH and water holding capacity was decreased and cooking loss was increased among different treatments significantly (p<0.05). Biochemical properties such as TBARS were increased significantly (p<0.05). Microbial qualities such as TCC, TVC and TYMC values showed significantly (p<0.05) higher value with the increase of days of storage. From these findings the nutritive value of doe liver is less decreased during 60 days storage so it is acceptable for human consumption but the third treatment as 120 days, its quality is deteriorated with the increase of storage time.
Seroprevalence of SARS-CoV-2 IgG antibodies among rural children aged 6-14 years in a selected block of West Bengal, India
Authors: Shukla Vineeta , Shukla Vivek , Basu Mausumi , Mondal Aparajita , Rashid Mamunur , Saha Ripan
Published: July 2024

Background and objectives: Children comprised a significant part of the population during the second and third waves of the COVID-19 pandemic. The objectives of this study were to estimate the seroprevalence of COVID-19 IgG antibody among the children aged 6 to 14 years and to determine, if any, the factors associated with seropositivity.

Methods: This cross-sectional study was conducted in a selected block of West Bengal, India over a period of 1 year (April 2022-March 2023) among children. Thirty villages in the block were selected by cluster sampling technique. COVID-19 IgM/IgG Rapid Antibody Test Kit (ICMR approved) was used for the detection of SARS-CoV-2 IgG antibodies. Data were analyzed by appropriate statistical tests.

Results: Total 600 children were enrolled in the study.SARS-CoV-2 IgG antibody was positive in 57.2% children. The seropositivity rate (91.8%) was significantly (p<0.001) high among children of age group 12 to 14 years. Seropositivity rate was not significantly different between male and female children (46.4% vs. 53.6%; p>0.05).

Conclusion: SARS-COV-2 IgG antibody was positive in a high proportion of children residing in rural areas indicating asymptomatic coronavirus infections among rural population. Socio-demographic factors such as higher age group and father’s education were significantly associated with seropositivity.

July 2024; Vol. 18(2):010. DOI:https://doi.org/10.55010/imcjms.18.022

*Correspondence: Vineeta Shukla, Department of Community Medicine, Infectious Diseases and Beliaghata General Hospital, Kolkata, India. Email: vineeta1992@gmail.com
Learning to Live with Osteoporosis: A Metaphoric Narrative
Authors: Hovey Richard , Craig Robert
Published: July 2024

A philosophical hermeneutic research approach was chosen to explore the meaning of living with osteoporosis, a degenerative bone disease. Osteoporosis creates the possibility of living with disabling physical, emotional, and social conditions for the person diagnosed with this serious health condition. The purpose of this study was to interpret the narratives authored by twelve participants living with osteoporosis. The findings provided in this article offer a perspective of how oneâ€™s shifting sense of self-renewal was expressed through osteoporosis-specific metaphors, which explicated a transformative process of how one learns to live well with osteoporosis. Three metaphors were identified and interpretively named the shattering, the surrendering, and the dance. An analysis, interpretation, and discussion of these narratives was performed. Consideration was given to how an interpretation of these findings, through metaphor, may benefit others living with osteoporosis, and how those diagnosed in the future can benefit from shared understandings and conversations about the meaning of living with osteoporosis. As people endeavored to make meaning of living with their illness, metaphors provided a useful common ground and invitation for discussion, story-telling, and the development of supportive relationships â€“ all implemented as educative methods to positively transition the impacted personsâ€™ physical, emotional, and social traumas toward the possibility of self-renewal.
The Privileges Chart in a Behaviour Class: Seeing the Power and Complexity of Dominant Traditions and Unconcealing Trust as Basic to Pedagogical Relationships
Authors: Gilham Christopher Matthew
Published: July 2024

Through an anecdote this interpretive work suggests that a chart on student privileges in a class for students with behavioural challenges led to an understanding of dominant traditions at play and the power such traditions can hold over educators. These complexly intertwined traditions included the efficiency movement, the norm, and market capitalismâ€™s emphasis on personal rights. These traditions set the conditions for an abused and exclusive notion of privileges for particular students. This led the teacher and me to question who decides student rights and for whom do such rights apply. We were then able to talk about how the teacher came to understand his students through pedagogical relationships built on trust rather than a singular belief in the rights of each student. This paper also attempts to show the above understandings involved an investigative labouring to dialogue with the topic and that such effort is worth-while because we were able to return to or recover some â€˜basicsâ€™ within pedagogical relationships. Keywords: behaviour, special education, interpretation, tradition, discourse, rights, trust, pedagogy
In Play, At Play
Authors: Laing Catherine Mohrea
Published: July 2024

Abstract It is surprising for many people to learn how restricted children with cancer are, both in their daily activities as well as in the bigger, more significant events in their lives.Â  The treatment for cancer often leaves children with significant immune suppression; exposure to any kind of virus or infection could lead to a life-threatening event.Â  Summer camp â€“ a â€œrite of passageâ€ for many kids â€“ would be a forgone experience were it not for specialized childrenâ€™s cancer camps. This paper is intended to interpretively examine the concept of play in relation to childrenâ€™s cancer camps. Much has been written about play both philosophically and scientifically, and while it might seem an obvious association, play and camp, I would suggest that like the word itself there is more complexity in this relationship than what first appears obvious.Â  Children play at camp, of course, but there is much â€œat playâ€ in them when they attend camp.Â  As Gadamer (1960/1989) wrote, â€œsomething is going onâ€¦something is happeningâ€ (p. 104).
Dr. David Jardine and the "Descartes Lecture": Twenty Years of Miraculous Returns
Authors: Moules Nancy J
Published: July 2024

http://hdl.handle.net/10515/sy5th8c32
From the "Science of Disease" to the "Understanding of Those Who Suffer": The Cultivation of an Interpretive Understanding of "Behaviour Problems" in Children
Authors: Gilham Christopher Matthew
Published: July 2024

In this interpretive essay, I attempt to unconceal the problematic history at play in Special Education in Alberta today, with a focus on â€œbehaviour studentsâ€ or their norm-referenced disability status. A brief, but central, anecdote is used to help reveal some of the everyday problems that arise in education because of the behavioural disability framing of students. I suggest that these problems are examples of Illichâ€™s appropriated notions of iatrogenesis and counterproductivity. As an applied emancipatory action, I call upon Gadamer and Ricoeur to help me interpretively turn the common, everyday understanding of pathology and self in the context of others as possibilities for understanding â€œbehaviour studentsâ€ anew.Keywords:behaviour, coding, dignity, disorder, iatrogenesis, self-esteem, special education
Social Work and Hermeneutic Phenomenology
Authors: Newberry Andrea Margaret
Published: July 2024

In this article, I discuss the connections between social work practice and interpretive approaches to knowledge building, introduce and situate hermeneutic phenomenology for novice social work researchers, and explore the fit between hermeneutic phenomenology and social work.Â  This paper also presents a historical, methodological, and philosophical overview of the roots of hermeneutic/interpretive phenomenology from Augustine to Sartre.Â  I advocate for the congruence between an hermeneutic approach and social work research due to its focus on inquiry as application, emphasis on the situated nature of human experiences, concept of attention to the unspoken or undisclosed, idea of the hermeneutic circle as a link between individual experiences and larger structures, fusion of horizons, and inclusion of the practitioner identity in research activities.
Teaching Science as a Hermeneutic Event
Authors: Pelech Sharon
Published: July 2024

In this article, the author explores the need for science education to be taught as a hermeneutic event, as opposed to a book of facts to be memorized. The fragmented, passive transmission of facts does not allow students to have a clear understanding of science, itsâ€™ traditions and how science lives in the world. By reconnecting biology back into the world and recognizing its creativity and uncertainty will help students understand how science impacts their lives and the world. The author explores how, through hermeneutics, students can experience the living discipline of science, as opposed to learning about science.
Scheler, Heidegger and the Hermeneutics of Value
Authors: Hackett J. Edward
Published: July 2024

In this paper, the author examines two different phenomenological frameworks for values: Heideggerâ€™s hermeneutic phenomenology and Schelerâ€™s phenomenology. Given the popularity of hermeneutic phenomenology inspired by Heideggerâ€™s efforts, the author openly questions if values can be accommodated in that framework. The author suggests that those paying attention to the lived-experience of values consider Schelerâ€™s phenomenology of value as a more refined alternative to make sense of value-experience and cultural practices more generally.KeywordsEthics, Givenness, Heidegger, Scheler, Value
"Isn't All of Oncology Hermeneutic?"
Authors: Moules Nancy J , Jardine David W , McCaffrey Graham P , Brown Christopher B
Published: July 2024

In this paper, we describe an event during a pediatric oncology research meeting that prompted the discussion of the ways in which hermeneutics brings a different kind of understanding to both research and practice. We claim that oncology is the practical science of handling natural science research and as such practice in oncology is deeply hermeneutic in character in its recognition of the importance, vitality, and generativity of the â€œindividual caseâ€ even in the face of amassed, verified, and aggregate knowledge that is given from the natural science research. Oncology is always contingent, next case handling, and is not identifiable simply as something determined and guided by natural sciences alone. In the face of this, we propose that there is an obvious, profound, and natural fit of hermeneutic research in understanding the lives, relationships, suffering, and experiences that are affected by cancer. Â  Keywords: childhood cancer, Gadamer, hermeneutics, pediatric oncology, Robert Buckman Â
Knowing Nothing: Understanding New Critical Social Work Practice
Authors: Gallop Cynthia Justine
Published: July 2024

Individuals embarking on their journey to become professional social workers often state they feel as if they know nothing upon entering their practice. Regardless of the number of years critical social workers have practiced, they are also thought to know â€œnothing.â€ By utilizing a philosophical hermeneutic approach I chose to recognize that new critical social work ideas, theories and practices come from something and somewhere (Moules, 2002). This hermeneutic study involved interviewing six newly graduated social workers from with a declared critical orientation. I asked these budding new professionals to describe what happens when they begin working in organizations that may or may not support a critical ideology and how this influences their practice. Hermeneutic interpretations of the participant experiences suggest that this â€œnothingâ€ is not devoid of meaning or method, but instead involves insinuating themselves and their ideas into their agencies in a delicate curvilinear manner.
The Island of Misfit Toys
Authors: Laing Catherine M. , Moules Nancy J.
Published: July 2024

A philosophical hermeneutic study was conducted to understand the meaning of childrenâ€™s cancer camps for the child with cancer and the family. Six families and five camp counselors were interviewed in order to bring understanding to this topic.Â  While the research included findings related to: the concept of play at cancer camp (both philosophically and scientifically); grief as something to live with versus â€œget overâ€; storytelling as a means of re-shaping and understanding traumatic experiences; and the solidarity of the community as one that creates intense, healing bonds, this paper will detail the finding related to the children and families experience of finding acceptance and fit at camp.