bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-Term Activation of Semicarbazide-Sensitive Amine Oxidase Lowers Circulating Levels of Uric Acid in Diabetic Conditions
Authors: CARPÉNÉ C. , DESQUESNES A. , GOMEZ-RUIZ A. , IFFIÚ-SOLTÉSZ Z. , LE GONIDEC S. , MERCADER J.
Published: April 2020

Uric acid is involved in nitrogenous waste in animals, together with ammonia and urea. Uric acid has also antioxidant properties and is a surrogate marker of metabolic syndrome. We observed that the elevated plasma uric acid of high-fat fed mice was normalized by benzylamine treatment. Indeed, benzylamine is the reference substrate of semicarbazide-sensitive amine oxidase (SSAO), an enzyme highly expressed in fat depots and vessels, which generates ammonia when catalysing oxidative deamination. Ammonia interferes with uric acid metabolism/solubility. Our aim was therefore to investigate whether the lowering action of benzylamine on uric acid was related to an improvement of diabetic complications, or was connected with SSAO-dependent ammonia production. First, we observed that benzylamine administration lowered plasma uric acid in diabetic db/db mice while it did not modify uric acid levels in normoglycemic and lean mice. In parallel, benzylamine improved the glycemic control in diabetic but not in normoglycemic mice, while plasma urea remained unaltered. Then, uric acid plasma levels were measured in mice invalidated for AOC3 gene, encoding for SSAO. These mice were unable to oxidize benzylamine but were not diabetic and exhibited unaltered plasma uric levels. Therefore, activated or abolished ammonia production by SSAO was without influence on uric acid in the context of normoglycemia. Our observations confirm that plasma uric acid increases with diabetes and can be normalized when glucose tolerance is improved. They also show that uric acid, a multifunctional metabolite at the crossroads of nitrogen waste and of antioxidant defences, can be influenced by SSAO, in a manner apparently related to changes in glucose homeostasis.
Atropa Belladonna L. Water Extract: Modulator of Extracellular Matrix Formation in Vitro and in Vivo
Authors: GÁL P. , VASILENKO T. , KOVÁČ I. , KOSTELNÍKOVÁ M. , JAKUBČO J. , SZABO P. , DVOŘÁNKOVÁ B. , SABOL F. , GABIUS H.-J. , SMETANA Jr. K.
Published: April 2020

Previously, we found that treatment of cutaneous wounds with Atropa belladonna L. (AB) revealed shortened process of acute inflammation as well as increased tensile strength and collagen deposition in healing skin wounds (Gál et al. 2009). To better understand AB effect on skin wound healing male Sprague-Dawley rats were submitted to one round full thickness skin wound on the back. In two experimental groups two different concentrations of AB extract were daily applied whereas the control group remained untreated. For histological evaluation samples were removed on day 21 after surgery and stained for wide spectrum cytokeratin, collagen III, fibronectin, galectin-1, and vimentin. In addition, in the in vitro study different concentration of AB extract were used to evaluate differences in HaCaT keratinocytes proliferation and differentiation by detection of Ki67 and keratin-19 expressions. Furthermore, to assess ECM formation of human dermal fibroblasts on the in vitro level fibronectin and galectin-1 were visualized. Our study showed that AB induces fibronectin and galectin-1 rich ECM formation in vitro and in vivo. In addition, the proliferation of keratinocytes was also increased. In conclusion, AB is an effective modulator of skin wound healing. Nevertheless, further research is needed to find optimal therapeutic concentration and exact underlying mechanism of action.
Age-Related Changes in Postural Responses to Backward Platform Translation
Authors: HALICKÁ Z. , LOBOTKOVÁ J. , BZDÚŠKOVÁ D. , HLAVAČKA F.
Published: April 2020

The aim of the study was to investigate age-related changes in postural responses to platform translation with 3 various velocities. We focused on the influence of linear velocity using the smoothed profile of platform acceleration (till 100 cm.s−2). Eleven healthy young (20-31 years) and eleven healthy elderly (65-76 years) subjects were examined. The subjects stood on the force platform with their eyes closed. Each trial (lasting for 8 sec) with different velocity (10, 15, 20 cm.s−1) of 20 cm backward platform translation was repeated 4 times. We have recorded displacements of the centre of pressure (CoP) and the EMG activity of gastrocnemius muscle (GS) and tibialis anterior muscle (TA). The results showed increased maximal values of CoP responses to the platform translation. There was also observed a scaling delay of CoP responses to platform translation with different velocities in elderly. The EMG activity of GS muscle during backward platform translation was of about similar shape in both groups during the slowest platform velocity, but it increased depending on rising velocity. EMG activity of TA was not related to the platform velocity. Early parts of postural responses showed significant co-activation of TA and GS muscles of elderly. It is likely that elderly increased body stiffening in order to help their further balance control.
Late Divergence of Target and Nontarget ERPs in a Visual Oddball Task
Authors: DAMBORSKÁ A. , BRÁZDIL M. , REKTOR I. , JANOUŠOVÁ E. , CHLÁDEK J. , KUKLETA M.
Published: April 2020

Different mental operations were expected in the late phase of intracerebral ERPs obtained in the visual oddball task with mental counting. Therefore we searched for late divergences of target and nontarget ERPs followed by components exceeding the temporal window of the P300 wave. Electrical activity from 152 brain regions of 14 epileptic patients was recorded by means of depth electrodes. Average target and nontarget records from 1800 ms long EEG periods free of epileptic activity were compared. Late divergence preceded by almost identical course of the target and nontarget ERPs was found in 16 brain regions of 6 patients. The mean latency of the divergence point was 570±93 ms after the stimulus onset. The target post-divergence section of the ERP differed from the nontarget one by opposite polarity, different latency of the components, or even different number of the components. Generators of post-divergence ERP components were found in the parahippocampal gyrus, superior, middle and inferior temporal gyri, amygdala, and fronto-orbital cortex. Finding of late divergence indicates that functional differences exist even not sooner than during the final phase of the task.
Central Corneal Thickness Considered an Index of Corneal Hydration of the UVB Irradiated Rabbit Cornea as Influenced by UVB Absorber
Authors: ČEJKA Č. , LUYCKX J. , ČEJKOVÁ J.
Published: April 2020

UVB radiation from sunlight induces an acute corneal inflammation, photokeratitis, accompanied by changes in corneal hydration. We employed a method of ultrasonic pachymetry for daily examination of central corneal thickness as an index of corneal hydration of the rabbit cornea repeatedly irradiated by UVB radiation (312 nm, daily dose of 0.25 J/cm2 during three or four days) as influenced by UVB absorber (actinoquinol combined with hyaluronic acid) dropped on the ocular surface during irradiation. One day after the third irradiation procedure the animals were sacrificed and corneas examined immuno-histochemically for peroxynitrite formation, a marker of oxidative damage, the antioxidant aldehyde dehydrogenase 3A1 and endothelial nitric oxide synthase, an enzyme generated nitric oxide. Results show that UV absorber combined with hyaluronic acid protected the cornea against UVB-induced changes in corneal thickness and microscopical disturbances to the cornea (both seen after buffered saline application) until the fourth experimental day. These UVB doses are equivalent to a daily exposure of 2.5 hrs of the human cornea to solar UVB radiation for three consecutive days. It is suggested that actinoquinol/ hyaluronic acid drops might be helpful for the human eye in the defence against photooxidative and other oxidative processes.
Development of Oxytocin- and Vasopressin-Network in the Supraoptic and Paraventricular Nuclei of Fetal Sheep
Authors: SHI L. , FAN Y. , XU Z.
Published: April 2020

The hypothalamic supraoptic and paraventricular nuclei consist of oxytocin and arginine vasopressin synthesizing neurons that send projections to the neurohypophysis. A growing body of evidence in adult animals and young animals at near term confirmed the structure and function in the vasopressinergic and oxytocinergic network. However, whether those distinctive neural networks are formed before near term is largely unknown. This study determined the special patterns in location and distribution of oxytocin- and vasopressin-neurons in the paraventricular and supraoptic nuclei from preterm to term in the ovine fetuses. The results showed that oxytocin- and vasopressin-neurons were present in both nuclei at the three gestational time periods (preterm, near term, and term). In the paraventricular nuclei, vasopressin-cells concentrated mainly in the core of the middle magnocellular paraventricular nuclei, and oxytocin-cells were scattered surrounding the core. In the supraoptic nuclei, vasopressin-cells mostly located in the ventral part, and oxytocin-cells in the dorsal part. The data demonstrated that the special distributed patterns of vasopressin- and oxytocin-neuron network have formed in those two nuclei at least from preterm. Intracerebroventricular injection of angiotensin II significantly increased fetal plasma oxytocin and vasopressin levels at preterm, which was associated with an increase of oxytocin- and vasopressin-neuron activity marked with c-fos expression. The data provided new evidence for the structural and functional development of the oxytocin- and vasopressin-network before birth.
An Antagonist of GABA-B Receptors Potentiates Activity of Cortical Epileptic Foci
Authors: MAREŠ P. , BERNÁŠKOVÁ K. , KUBOVÁ H.
Published: April 2020

Cortical epileptic foci elicited by local application of bicuculline methiodide represent a model of interictal epileptic activity with a transition into ictal phases. We studied a role of GABA-B receptors in this model using GABA-B receptor antagonist CGP35348 in adult rats with implanted cortical electrodes and cannula. CGP35348 (100 or 200 mg/kg i.p.) did not affect interictal discharges but it augmented ictal activity. Latency to the first ictal episode was decreased by the lower dose of CGP35348, duration of episodes was increased by the higher dose. GABA-B receptor antagonist did not influence purely cortical epileptic phenomenon but it is proconvulsant in ictal activity generated with participation of subcortical structures.
T2D Risk Haplotypes of the TCF7L2 Gene in the Czech Population Sample: the Association With Free Fatty Acids Composition
Authors: VČELÁK J. , VEJRAŽKOVÁ D. , VAŇKOVÁ M. , LUKÁŠOVÁ P. , BRADNOVÁ O. , HÁLKOVÁ T. , BEŠŤÁK J. , ANDĚLOVÁ K. , KVASNIČKOVÁ H. , HOSKOVCOVÁ P. , VONDRA K. , VRBÍKOVÁ J. , BENDLOVÁ B.
Published: April 2020

The association of transcription factor 7-like 2 (TCF7L2) gene variants with the pathogenesis of T2D, gestational diabetes and polycystic ovary syndrome (PCOS) was examined. The study involved 1460 individuals: 347 T2D patients (D); 261 gestational diabetics (G); 147 offspring of T2D (O); 329 women with PCOS, and 376 controls (C). The SNPs: rs7901695; rs7903146; rs12255372 in the TCF7L2 gene were genotyped. Anthropometric and biochemical parameters, oGTT derived indices were assessed. In addition, free fatty acids (FFAs) were evaluated in 183 non-diabetic women. The CTT haplotype showed the strongest association with T2D with OR 1.57, p=0.0003. The frequency of the CTT/CTT haplotype was decreasing in following order: D 10.6, O 9.5, G 6.1, C 5.3 and PCOS 4.9 [%]. Among CTT carriers, significantly decreased levels of oGTT-stimulated insulin and C-peptide as well as proportions of fasting PUFAs were observed. The carriership of CTG/TCG was associated with gestational diabetes, OR 2.59, p=0.036. The association of TCF7L2 haplotypes with T2D and gestational diabetes but not with PCOS was confirmed. Novel association of TCF7L2 with FFAs composition was found.
Autophagy-Lysosomal Pathway Is Involved in Lipid Degradation in Rat Liver
Authors: ŠKOP V. , CAHOVÁ M. , PAPÁČKOVÁ Z. , PÁLENÍČKOVÁ E. , DAŇKOVÁ H. , BARANOWSKI M. , ZABIELSKI P. , ŽDYCHOVÁ J. , ZÍDKOVÁ J. , KAZDOVÁ L.
Published: April 2020

We present data supporting the hypothesis that the lysosomal-autophagy pathway is involved in the degradation of intracellular triacylglycerols in the liver. In primary hepatocytes cultivated in the absence of exogenous fatty acids (FFA), both inhibition of autophagy flux (asparagine) or lysosomal activity (chloroquine) decreased secretion of VLDL (very low density lipoproteins) and formation of FFA oxidative products while the stimulation of autophagy by rapamycine increased some of these parameters. Effect of rapamycine was completely abolished by inactivation of lysosomes. Similarly, when autophagic activity was influenced by cultivating the hepatocytes in “starving” (amino-acid poor medium) or “fed” (serum-supplemented medium) conditions, VLDL secretion and FFA oxidation mirrored the changes in autophagy being higher in starvation and lower in fed state. Autophagy inhibition as well as lysosomal inactivation depressed FFA and DAG (diacylglycerol) formation in liver slices in vitro. In vivo, intensity of lysosomal lipid degradation depends on the formation of autophagolysosomes, i.e. structures bringing the substrate for degradation and lysosomal enzymes into contact. We demonstrated that lysosomal lipase (LAL) activity in liver autophagolysosomal fraction was up-regulated in fasting and down-regulated in fed state together with the increased translocation of LAL and LAMP2 proteins from lysosomal pool to this fraction. Changes in autophagy intensity (LC3-II/LC3-I ratio) followed a similar pattern.
Dependence of Spontaneous Electrical Activity and Basal Prolactin Release on Nonselective Cation Channels in Pituitary Lactotrophs
Authors: KUČKA M. , KRETSCHMANNOVÁ K. , STOJILKOVIC S. S. , ZEMKOVÁ H. , TOMIĆ M.
Published: April 2020

All secretory anterior pituitary cells fire action potentials spontaneously and exhibit a high resting cation conductance, but the channels involved in the background permeability have not been identified. In cultured lactotrophs and immortalized GH3 cells, replacement of extracellular Na+ with large organic cations, but not blockade of voltage-gated Na+ influx, led to an instantaneous hyperpolarization of cell membranes that was associated with a cessation of spontaneous firing. When cells were clamped at –50 mV, which was close to the resting membrane potential in these cells, replacement of bath Na+ with organic cations resulted in an outward-like current, reflecting an inhibition of the inward holding membrane current and indicating loss of a background-depolarizing conductance. Quantitative RT-PCR analysis revealed the high expression of mRNA transcripts for TRPC1 and much lower expression of TRPC6 in both lactotrophs and GH3 cells. Very low expression of TRPC3, TRPC4, and TRPC5 mRNA transcripts were also present in pituitary but not GH3 cells. 2-APB and SKF-96365, relatively selective blockers of TRPC channels, inhibited electrical activity, Ca2+ influx and prolactin release in a concentration-dependent manner. Gd3+, a common Ca2+ channel blocker, and flufenamic acid, an inhibitor of non-selective cation channels, also inhibited electrical activity, Ca2+ influx and prolactin release. These results indicate that nonselective cation channels, presumably belonging to the TRPC family, contribute to the background depolarizing conductance and firing of action potentials with consequent contribution to Ca2+ influx and hormone release in lactotrophs and GH3 cells.
Idebenone-Induced Recovery of Glycerol-3-Phosphate and Succinate Oxidation Inhibited by Digitonin
Authors: RAUCHOVÁ H. , VOKURKOVÁ M. , DRAHOTA Z.
Published: April 2020

Digitonin solubilizes mitochondrial membrane, breaks the integrity of the respiratory chain and releases two mobile redox-active components: coenzyme Q (CoQ) and cytochrome c (cyt c). In the present study we report the inhibition of glycerol-3-phosphate- and succinate-dependent oxygen consumption rates by digitonin treatment. Our results show that the inhibition of oxygen consumption rates is recovered by the addition of exogenous synthetic analog of CoQ idebenone (hydroxydecyl-ubiquinone; IDB) and cyt c. Glycerol-3-phosphate oxidation rate is recovered to 148 % of control values, whereas succinate-dependent oxidation rate only to 68 %. We find a similar effect on the activities of glycerol-3-phosphate and succinate cytochrome c oxidoreductase. Our results also indicate that succinate-dependent oxidation is less sensitive to digitonin treatment and less activated by IDB in comparison with glycerol-3-phosphate-dependent oxidation. These findings might indicate the different mechanism of the electron transfer from two flavoprotein-dependent dehydrogenases (glycerol-3-phosphate dehydrogenase and succinate dehydrogenase) localized on the outer and inner face of the inner mitochondrial membrane, respectively.
Partial Agonist of Benzodiazepine Receptors Ro 19-2088 Elicits Withdrawal Symptoms After Short-Term Administration in Immature Rats
Authors: KUBOVÁ H. , MAREŠ P.
Published: April 2020

Repeated administration of partial agonist of benzodiazepine receptors Ro 19-8022 (a derivative of quinolizine class) does not elicit withdrawal in adult rats. Our older data demonstrated that single injection of Ro 19-2088 to immature rats induces increased sensitivity to convulsant action of pentylenetetrazol as a withdrawal phenomenon. To know if repeated administration of the partial agonist has the same effect we injected rats at postnatal days 7 to 11 with an anticonvulsant dose of Ro 19-2088 (0.5 mg/kg i.p.) and tested them 24 h, 48 h and 4 days after the last injection. Repeated administration of Ro 19-8022 resulted also in an increased sensitivity to convulsant action of pentylenetetrazol in immature rats (higher incidence and severity of seizures). This effect was significant 24 h after the last injection but only outlined 48 h after administration. No signs of hypersensitivity were seen at 4-day interval. There is a difference between immature and adult brain in an appearance of withdrawal symptom after administration of the partial agonist of benzodiazepine receptors Ro 19-2088.
RANCANG BANGUN SISTEM PEMASARAN PROPERTI BERBASIS WEB
Authors: Herdiansah Arief , Handayani Tuti , Yunita Elsya
Published: April 2020

Information technology is growing rapidly now, with technological advances everything can be achieved and reached very practically. Today many people spend their time using mobile phones / smartphones to view various online media, and one of them is advertising. PT Akila Trijaya is a property company, the company sees that currently the promotion method has not been carried out effectively, therefore the Company wants to utilize information technology in marketing its housing products known as Akila Residence in Serang City. To meet these needs, researchers took the initiative to design a web-based property information system created using the PHP programming language with the Mysql database. The researcher analyzes the current system using the SWOT analysis method. In the system design process, researchers use the Unified Modeling Language (UML) to create a marketing system design. The system testing method used is black box testing. This research has produced a web-based property marketing system that can help PT Akila Trijaya's to sell the Akila Residence.
Prediksi Ketepatan Waktu Lulus Mahasiswa Menggunakan Algoritma C4.5 Pada Fakultas Dakwah Dan Ilmu Komunikasi UIN Raden Intan Lampung
Authors: Satria Fiqih , Zamhariri Zamhariri , Syaripudin M Apun
Published: April 2020

Student graduation data is very important for universities because it is used in the accreditation process. Data continues to grow and is ignored because it is rarely used. Data of graduating students can provide useful information if processed optimally. This study processes data using data mining to obtain information in the form of a prediction of student graduation punctuality. The method used is the C4.5 algorithm. The criteria used are gender, regional origin, type of school origin, ranking and entry point. In its application, the C4.5 algorithm can be used in predicting student graduation times with a precision value of 70.70%, 60.4% recall, and 58.2% accuracy. In measuring the performance of the algorithm in pattern recognition or information retrieval it is recommended to use a minimum of two parameters namely precission and recall to detect bias, therefore in this study the F-Measure calculation is used. From the calculation of the F-Measure obtained a value of 71% which means that the C4.5 algorithm is considered good in classifying and predicting students who graduate on time
MODEL INFORMATION DASHBOARD NILAI SISWA: TOOLS MONITORING HASIL BELAJAR
Authors: Fahrezy Husein Muhammad , Silaen Toga Parlindungan , Henderi Henderi
Published: April 2020

In teaching and learning activities it is necessary to have monitoring activities carried out by teachers to the principal, so that the teaching staff know the values and limits of the ability of their students. The process of delivering information about the grades of students to the principal is still manually and less than optimal. So we need a system that makes it easy for teachers to monitor their students. Therefore, the discussion in this paper is to design a dashboard information model that will facilitate collaboration between teachers and monitor the development of students' abilities by the principal. This research uses the needs analysis, planning, prototype design and prototype review methods. So the data displayed will be in accordance with what is needed by the school. With the dashboard information will provide teaching staff information that is as needed, interactive and more efficient.
ANALISIS PERFORMA PERANGKAT LUNAK ANTIVIRUS DENGAN MENGGUNAKAN METODOLOGI PENGUKURAN PERFORMANCE
Authors: Kurniawati Ana , Ardiansyah Ardiansyah
Published: April 2020

This research aims to observe the performance of licensed enterprise antivirus software. The company Antivirus researched is Trend Micro Worry-Free Service and Kaspersky Endpoint Security. To get the data done testing on the specified antivirus parameters using the help of tools like Rebooter, BootRacer, Teracopy, Process Explorer and IP Messenger. Testing both antivirus software did as many as 8 parameters are boot time, restart, full scan, copy-paste files and use memory capacity during a full scan or when idle. The results of the data found at random are analyzed with statistical tests using Test T and test F. Tests conducted to indicate there is no significant average score difference from the test result value of 8 antivirus parameters. The result of the T-Test statistical analysis and F-test is that both anti-virus product has the advantages and disadvantages in each of the parameters with the speed of time and memory capacity used. But when calculated as a whole, antivirus Kaspersky Endpoint Security becomes the best antivirus performance.
PENGARUH E-SERVICE QUALITY DAN E-TRUST TERHADAP KEPUASAN NASABAH PENGGUNA BNI MOBILE BANKING MELALUI CITRA BANK SEBAGAI VARIABEL INTERVENING
Authors: Nawangasari Sri , Putri Nadea Dwirahma
Published: April 2020

This study aims to determine the effect of e-service quality and e-trust on customer satisfaction of BNI Mobile banking users through the image of the bank as an intervening variable. Data used in this study are primary data, data collection through questionnaires with a total sample of 185 respondents who are "BNI Mobile banking" customers use a purposive sampling technique. Analysis of the data used is descriptive analysis and path analysis. The results showed that: The e-service quality variable directly affected the customer satisfaction variable; The e-trust variable directly influences the customer satisfaction variable; e-service quality variables affect the image of the bank, e-trust variables affect the image of the bank, and the image of the bank affect customer satisfaction. Thus, BNI Bank should continue to improve service quality and trust in the Bank so that customers feel satisfied so that the bank's reputation is better.
Penerapan Metode EPQ(Economic Production Quantity) Pada Pengendalian Bahan Baku Laundry Di Samarinda Laundry Mart Barbasis Android
Authors: Ekawati Hanifah , Adytia Pitrasacha , Yunita Yunita
Published: April 2020

Samarinda Laundry Mart is a business that provides laundry services, besides that it is also a supplier of laundry raw materials in Samarinda. Control of laundry raw materials in the laundry business is a complicated problem. Therefore one method that can be used for raw material control is the EPQ method (Economic Production Quantity) where the EPQ method can determine the optimal production level, optimal production frequency, optimal time cycle to minimize total inventory costs. The results of this study are made inventory control applications using the EPQ method that can make calculations automatically. Only by entering monthly data that is already available. Users can also make transactions using the application so that all data has been integrated in the database to facilitate management in the laundry business. In addition, this application can also print transaction reports and turnover reports.
Klasifikasi Penentuan Pengajuan Kartu Kredit Menggunakan K-Nearest Neighbor
Authors: Kurniawan Yogiek Indra , Barokah Tiyssa Indah
Published: April 2020

A credit card is a device payment issued by the bank certain made of plastic and useful as a tool payment on credit carried out by the owner of the card or in accordance with the name of listed in a credit card is on when making purchases goods or services. The problems facing in giving a credit cards to customers bank that have signed up is difficult to determine the category of a credit cards in accordance with the customer bank. By doing this research is expected to facilitate the bank or the analysis to determine the category of a credit card to customers bank right. The research used is by applying methods K-Nearest Neighbor to classify prospective customers in the making a credit card in accordance with the category of  customers by using data customers at the Bank BNI Syariah Surabaya. A method K-Nearest Neighbor used to seek patterns on the data customers so established variable as factors supporters in the form of gender, the status of the house, the status, the number of dependants (children), a profession and revenue annually. The results of this research shows that an average of the value of precision of 92%, the value of recall of 83%, and the value of accuracy of 93%. Thus, this application is effective to help analyst credit cards in classifying customers to get credit cards that appropriate criteria.
IMPLEMENTASI SIG UNTUK PEMETAAN USAHA MIKRO, KECIL DAN MENENGAH (UMKM) PRODUK KHAS KOTA PALEMBANG
Authors: Agustini Eka Puji
Published: April 2020

Geographically the area of Palembang City is 400.61 km2 which is divided into 16 subdistricts and 107 villages and has a sizeable population. The Office of Cooperatives, Small and Medium Enterprises in Trade and Industry of Palembang City as an office directly related UMKM has mapped UMKM in Palembang City but this mapping is still limited to reporting, and is not yet widely accessible to the public. Therefore this study aims to map UMKM geographically and publicly accessible. This mapping will be built using Arcgis technology and Geographic Information System which is an application of earth data processing by looking at spatial data and attribute data. The results of this study are in the form of a GIS application that maps the UMKM of Palembang City.
MEMBANGUN WEBSITE PROFILE KELURAHAN MELAYU TENGGARONG
Authors: Yulindawati Yulindawati , Ekawati Hanifah
Published: April 2020

The research to build Website Profile of Tenggarong Kelurahan is a study to facilitate the public to obtain complete and up-to-date information because the information is felt to be very important in decision making and in achieving goals. In addition to obtaining complete and up-to-date information, the website can also send and publish information to the wider community online. The system development method used in this research is the System Development Life Cycle (SDLC) method, or better known as the system development life cycle in system engineering and software engineering, is the process of making and changing systems and the models and methodologies used to develop these systems. The long-term goal to be achieved is that it is hoped that this system will be able to publicize its activities for more up-to-date information so that the public can find out about the activities that have been carried out, ease of information on the procedures for handling correspondence in the Melayu Tenggarong village to the public at large. So that the specific target of using the Tenggarong Kelurahan website as an effective medium for delivering information can be achieved.
Prototype Rancang Bangun Robot Penyiram Tanaman Otomatis Dengan Kendali Fuzzy
Authors: Ekaprasetyo Akmal , Pambudi Wahyu Setyo
Published: April 2020

Robot is a mechanical device that can perform physical tasks, both with human supervision and control (semi-automatic), or with a program that has been defined in advance (artificial intelligence). Robots are usually used for heavy tasks, repetitive and monotonous work such as cleaning up toxic wastes, underwater and space exploration, mining, search and rescue, and in agriculture. The agricultural robot designed is a four-wheeled mobile robot that can water plants automatically by taking into account the temperature and soil humidity. This agricultural robot design uses line follower system (line follower robot) and wireless communication through ESP8266. The robot detects the temperature and soil humidity through LM35 and YL-69 sensors which are readable through ATmega32 microcontroller  programmed by C programming language.
FAKTOR YANG MEMPENGARUHI KEPUASAN PENGGUNA SITUS BELANJA
Authors: Wibowo Yudi Wahyu
Published: April 2020

Satisfaction is one sign of the success of a product or service in this case in the form of online shopping sites. Satisfaction assessed if users feel the achievement of a goal from the user. This study aimed to analyze the influence of variables contained in an online shopping website that quality systems, quality of information, perception of usefulness, ease of use to the user satisfaction. This research used experimental methods and quantitative data in the form of a questionnaire. The results showed that the three hypotheses were rejected and 4 received. Results of the data analysis using methods DeLone and McLean combined with Technology Acceptance Model (TAM) and PLS SEM showed that the three factors that influence user satisfaction is the quality of the system, perceived ease of use and perceived usefulness.
RANCANGAN SISTEM INFORMASI PENDAFTARAN SISWA BARU BERBASIS WEB PADA SMK PUTRA RIFARA
Authors: Maghfiroh Ainiyatul , Henderi Henderi , Maulani Giandari
Published: April 2020

New student registration is one of the processes that is normally carried out every year in educational institutions such as schools. New student registration is useful for screening prospective students who have been selected tobecome their students. In this research the process of registering new students at SMK Putra Rifara is done conventionally and has not been computerized, which allows many errors from writing data, stacking files and losing data. The formulation of the problem of this research is how to make a registration information system for SMK Putra Rifara. So the research method used is the method of observation, interviews, and library methods. The new student registration in formation system is buit with the PHP programming language and utilizes the MySQL database as a database server. The results of this study are web-based new student registration information systems that have the ability to provide data accuracy and ease for parents and prospective new students to obtain information about the school.
APLIKASI UJIAN ONLINE BERBASIS WEB DI SMA BHAKTI NUSANTARA PALEMBANG
Authors: Sopiah Nyimas , Amanda Muhammad Theda , Aminto Muhammad Theda , Al Mubarokah Alfi Brilian , Herawati Yusriah
Published: April 2020

Palembang Bhakti Nusantara High School is one of the High Schools (SMA) that has used information technology in certain activities. Palembang's Bhakti Nusantara High School utilizes technology to facilitate teaching and learning by applying the Online Examination. At present, the exam still conducts tests using paper so that there is a need for further development to help and improve the effectiveness and efficiency of performance carried out in accordance with the business processes that run at the Bhakti Nusantara Palembang High School. This Online Examination is used to facilitate the management of master data needed to support the examination activities and the management of exam master data values. The software development method used is the web engineering method. This Online Examination implementation uses PHP, HTML, CSS, Javascript and MySQL Database Management System (DBMS).
PENGEMBANGAN PERANGKAT LUNAK MONITORING WELLIES DENGAN METODE WATERFALL MODEL
Authors: Tujni Baibul , Hutrianto Hutrianto
Published: April 2020

Work is a necessity and routine for everyone. In doing ordinary work there are agencies where someone works. One of the workplaces is ConocoPhilips Suban. The existing work is to secure the goods in each wellies. Currently in the process of monitoring existing goods in the ConocoPililips Suban willes is still being done conventionally, especially the situation report for each wellies owned. For this reason, in this study the development of software used to monitor and manage the willes guarding schedule and find out the identity of anyone on duty in order to improve the performance of the members of guard. The software development used in this study is the waterfall model. Waterfall is a structured software development method with five stages namely communication, planning, modeling, construction and deployment. The results of the research are monitoring wellies software with three types of users, namely admin, patrol officer, guard officer. The software also has a menu in the form of data management officers, wellies, goods, and reports. The software has two types of display interfaces namely web-based used for admin type users and mobile interfaces used for officer type users. The results also showed that the software was able to monitor goods in each wellies so that the reporting carried out had good accuracy values.

 

Abstrak: Pekerjaan merupakan kebutuhan dan rutinitas septiap orang. Dalam melakukan pekerjaan biasaya terdapat instansi tempat seseorang bekerja. Salah satu tempat kerja yang adalah ConocoPhilips Suban. Pekerjaan yang ada yaitu melakukan pengamanan barang yang ada pada setiap wellies. Saat ini dalam proses monitoring barang yang ada pada  willes ConocoPhilips Suban masih dilakukan secara konvensional terutama laporan keadaan untuk setiap wellies yang dimiliki. Untuk itu di dalam penelitian ini dilakukan pengembangan perangkat lunak yang digunakan untuk monitoring dan mengatur jadwal penjagaan willes serta mengetahui identias siapa saja yang bertugas agar dapat meningkatkan kinerja para anggota penjagaan. Pengembangan perangkat lunak yang digunakan dalam penelitian ini adalah waterfall model. Waterfall merupakan metode pengembangan perangkat lunak yang terstruktur dengan lima tahapan yaitu komunikasi, perencanaan, pemodelan, konstruksi dan deployment. Hasi dari penelitian berupa perangkat lunak monitoring wellies dengan tiga jenis pengguna yaitu admin, petugas patroli, petugas jaga. Perangkat lunak juga memiliki menu berupa pengelolaan data petugas, wellies, barang, dan laporan. Perangkat lunak memiliki dua jenis tampilan antarmuka yaitu berbasis web yang digunakan untuk pengguna jenis admin dan antarmuka mobile yang digunakan untuk pengguna jenis petugas. Hasil penelitian juga menunjukkan bahwa perangkat lunak mampu untuk melakukan monitoring barang pada setiap wellies sehingga pelaporan yang dilakukan memiliki nila akurasi yang baik.
Alien—Different—One’s Own. Ethnocultural frontier: conceptual, typological, and situational aspects
Authors: Barabash Yurii
Published: April 2020

This is the first paper of the three-issue series about the ethnocultural frontier planned by the author. A long time ago, the scholarly discussions on the problems of the frontier, which became quite vivid in the last decades, had overcome the initial relatively local frames of the American ‘thesis of the frontier’ connected with the specific conditions and circumstances of the Wild West epoch. Currently, these discussions cover various fields of humanities and are becoming more relevant at the present stage of the global historical development, as they signal new civilizational traits and specific features of this stage. By this, the author implies globalization and glocalization processes that encompass multiplicity and variability, also unpredictability, oddity, and non-stability of combinations as well as the diversity of ambivalent forms and transitive states emerging on this basis. The paper defines key theoretical and methodological principles forming the intentional (according to R. Carnap) approach to the concept of the frontier; it also suggests a number of typological models of the ethnocultural frontier (frontier literary zones; transitive periods and states in the historicalliterary process, as well as in the language sphere, in creative work, and psychology of an author; comparative collations, etc.). Finally, it analyzes selected literary cases that emerged in geopolitical and ethnocultural zones of Ukraine (namely Austro-Ukrainian and Polish-Ukrainian frontiers) within the framework ‘Alien — Different — One’s own’. The analysis, both diachronic and synchronic, considers contextual factors, i.e. genetic, historical, geopolitical, international, ideological, and sociocultural contexts. In the following two papers of the series, the author intends to deal with the eastern ethno- and linguocultural frontier of Ukraine (Kharkiv, Donbas) and the Ukrainian-Jewish literary frontier.
‘Text as condenser of cultural memory’: intertextual space of Valerii Shevchuk’s prose
Authors: Prylipko Iryna
Published: April 2020

The paper considers the demonstrative aspects of intertext in the prose by Valerii Shevchuk and focuses on the peculiarities of the works’ interaction with the Bible, mythology, and literature, which takes place at the level of different forms and types of intertext. Particular attention is paid to revealing the specifc ‘dialogue’ of V. Shevchuk’s works with their pretexts — hagiography, autobiographical and diary’s literature of Baroque. ɒ e examples discussed testify to the depth and ramifications of the intertextual dialogue in the writer’s prose, reveal the intellectual, philosophical, and elitist nature of his texts. A dialogue with the Bible, mythology, world and Ukrainian literature in the works by V. Shevchuk unfolds in the form of open and hidden quotations, allusions, reminiscences. These details aim at deepening the representation of ideas and themes, forming the subtexts, interpreting images. The writer creates a new artistic form — metatext — mainly through the reinterpretation of the pretexts, among which the works of the Baroque period (poetic, autobiographical, diary genres) and hagiography dominate. Transforming the pretexts at the level of contents, plot, genre, time and space, narrative, V. Shevchuk expands them with monologues, dialogues, descriptions, and details. In the process of interpreting prototexts, the writer resorts to modeling original images, in the context of which he actualizes some worldview points, reveals important moral, ethical, and philosophical problems. Allowing the perception of his work as a ‘textual game’, the writer, at the same time, does not reduce the role of intertext to the level of intellectual play. Intertext becomes a peculiar way of continuing the literary discourses of the past in a dialogue with them. They become re-read, ‘supplemented’ and thus brought once again into the continuous process of forming culture.
New hero in war prose of present time (based on books about war in Donbas)
Authors: Herasymenko Nina
Published: April 2020

The events on Maidan, the Russian-Ukrainian war in the East of Ukraine became a particular challenge not only for the novice writers but also for the famous masters of the word. Some of them took part in the defense of the country; others were strictly focused on the contemporary situation and talked with the soldiers who returned from the front.  New works with scary stories and unexpected solutions aroused. In addition to the common theme, these books, published in 2014–2018, showed another common longed-for phenomenon – the emergence of a new hero. He is a patriot who, with weapons in hands, defends the homeland in Donbas, his own choice and future. He is a well-educated young man with a strong pro-Ukrainian position who is proud of his nationality. He has the power to design and successfully conduct a military special operation. Now he is ready for changes within society, he is savvy in questions of politics and course of Ukraine in the international arena. He is characterized by determination and perseverance, he is ready to fight. The new hero does not trust the central government since during all the years of independence it demonstrated to its own people only political weakness and double standards. An ordinary Ukrainian might be used to adjust himself to all the authorities without exception. However, the events of Maidan, and then the war woke up the society and swept its apathy. The desire to defend oneself, one’s family and friends, and the whole country gave strength to the people. Thus a new, self-confident and strong Ukrainian became typical. He is a leader able to motivate his comrades for being active in the battlefield and politics.The new hero may have even some messianic features corresponding to the people’s expectations.
Biographical narrative in diaries of Dymytrii Tuptalo and Taras Shevchenko
Authors: Lebid-Hrebeniuk Yevheniia
Published: April 2020

The paper deals with a specific genre of diary in the heritage of D. Tuptalo and T. Shevchenko. The comparative analysis allowed the researcher to clarify the nature of the genre and define its basic characteristics. Special attention has been paid to the general features in both diaries, such as language, orientation towards a future reader, the atmosphere of ‘expectation’. In both diaries, the authors present themselves as a part of the action and even heroes of the stories. Thus a description of all events is typically given from the author’s perspective; the author and the narrator merge in a first-person narrative. The communicative techniques in the structure of the text are described briefly; these are comparison, evaluative judgments, the image of the Other, speaking to the reader, etc. The researcher interprets some theses about writers’ views concerning religion, friendship, and the phenomenon of silence. The character of such silence in the text is multidimensional: the varieties of literary pause/silence may be found throughout the diaries; the figures expressing silence belong to several types. The meaning of silence shifts according to the context. Some specific discoveries are based on such common features in both diaries as critical thinking, engaging the reader in the text, deep existential thoughts, digression (a partial retreat from the main theme in the text). The comparison of Tuptalo’s and Shevchenko’s texts allows seeing how the genre of a writer’s diary was shaped in Ukrainian literature.
APPLICATION OF MATHEMATICAL MODELING TO STUDY THE POPULATION GROWTH OF SERGIPE
Authors: Junior Romualdo S.S.
Published: April 2020

Knowledge of population growth of a particular region is of great importance for the political interests are reassessed and refocused. The objective of this work is to use the Malthusian model that takes into account the mathematical tool of Differential equations, in particular the separation of variables, and apply to the study of population growth in the state of Sergipe. The results showed significantly close to the estimated values by the IBGE (Brazilian Institute of Geography and Statistics). It is observed, that the forecast population growth for Sergipe has de-creased, changing from continuous to a discrete model by the year 2050.
Oruwari-Briggs house and the evolution of contemporary Kalabari society
Authors: Asuk Otokpom Charles
Published: April 2020

The evolution of contemporary Kalabari society reflects the contour of a historical progression of a people who struggled to manage the competing forces of unity and disunity in their existence. As a polity, it evolved from a fishing village to a city-state, to an empire, and to a republic or confederacy. This work examines the role of Oruwari-Briggs House in this evolutionary trajectory from the pre-colonial through the colonial to the post-colonial period. Methodologically, the work adopts the political economy approach. From oral and archival sources, published and unpublished works, the study demonstrates that the Oruwari-Briggs House played a strategic role in the inter-house rivalry, the formation of groups, and political alliances that culminated in the disintegration of Elem Kalabari, movement of populations to new settlements, the transformation of traditional political institutions, and the emergence of multiple centers of power symbolized by the existence of Amayanapu in contemporary Kalabari as against an Amayanabo for the entire polity in the pre-colonial period.
Creation accounts in Gen. 1 & 2: a feminist interpretation
Authors: Eyo Ubong Ekpenyong
Published: April 2020

It is the view of most people who claim the authoritative nature of the Bible that, women assigned secondary status in relation to men is ordained and supported in the Bible. Many have quoted different texts of the holy writ to support their culturally-biased position on issue of gender equality. Most often views in respect to gender issues are culturally-based and interpreted rather than divinely-based and interpreted. There is therefore the need to look back at Jesus’ words, “But at the beginning of creation God 'made them male and female.” (Matt 19:4; Mark 10:6 King James Version). The two accounts in the Book of Genesis by the Priestly and Yahwistic strands give a complimentary account of the creation of humankind (both male and female) in the image and likeness of God and their creation from a single stock אדם who was not a male gender. At a cursory reading of the creation accounts, one will tend to see האדם as the male gender, but looking at the Hebrew text more closely it will be noticed that the Hebrew words אישה and אישwere only introduced after the two genders have been separated. Note carefully that it was not איש that was asked to tend the garden, who named the animals, was given instruction of what to eat or what not to eat, who fell into a deep sleep or whose ribs was used in the creation of אישה but it was האדם . It was after the creation or ‘separation’ of אישה (woman – the female האדם) that the other part was called איש (man – the male האדם) (see vv 23 & 24 King James Version). It will therefore not be right to speak of the creation of אישה out of איש, because as at the time of the creation of the former, the later was not in existence as איש To view these creation accounts with the sense of gender superiority (either male over female or vice versa) is to read the texts using lenses which have been obscured and tainted by patriarchal, matriarchal or cultural biases.