bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Rajat bhasma and Sweta musali in the management of Ksheenasukra with special reference to oligospermia – A randomized comparative open clinical trial
Authors: Kumbhar Prakash Ashok , V G Huddar , N N Sukumar
Published: October 2022

Background: Male infertility can be defined as an inability to induce conception due to defect in spermatic functions. It is multifactorial condition. In more than 90% of cases, except some physical sperm defects low sperm count and poor sperm quality are responsible for the male infertility in more than 90% of cases. Sperm count less than 20 million/ml is considered as oligospermia. It is correlated to Kshinasukra condition. It is pathological condition of Sukra in which there may be reduced sperm count. In classics many Sukra-janaka (aphrodisiac) drugs have been explained in Kshinasukra. As Sweta musali and Rajata bhasma are explained as vrisya drugs and widely used by practitioners in the management of male infertility. So, present study wasaimedto know the effect of these drugs in the management of oligospermia. Methodology: Diagnosed cases of oligozoospermia were included in the study and divided into two groups by following a block randomization method. Group A received Sweta musali 10gms and Group B received Rajata bhasma 60mg daily for the duration of two months. Semen analysis was done before treatment and till the completion of study at the interval of 30 days. Results and conclusion: Sweta musali and Rajata bhasma were shown significant improvement in the sperm count, total motility and total abnormality as p<0.05. Comparative effect of drugs was shown almost similar effect on seminal parameters with mild variation.
Characterization of Copper-based Ayurved Medicine Tamra bhasma produced by various manufacturers and its Pharmacokinetic profiling in Wistar rat
Authors: Waghmare Chaitali S , Bidve Shivcharan , R V Gudi , Chawda Mukesh B , Yadav Santosh
Published: October 2022

Background: Tamra bhasma (TB) is copper based herbo-metallic preparation which is used extensively by Ayurvedic practitioners. Tamra bhasma is endorsed for different disorders of liver, abdominal pain, heart disease, colitis, tumors, anemia, loss of appetite, tuberculosis, as well as eye problems. Objective: Our aim is to characterize 5 commercial TB preparations from 5 different manufacturers by using modern scientific techniques and to study there bioavailability in Wistar rats. Materials and Methods: Tamra bhasma was characterized by X-ray diffraction (XRD), Scanning electron microscope (SEM), Energy Dispersive X-ray analysis (EDAX), Nanoparticle tracking analyzer (NTA), Inductively coupled plasma optical emission spectroscopy (ICP-OES). Bioavailability of Tamra bhasma was studies using non compartmental rat model with daily dose of 6.45mg/kg according to their body weight. Results: The colour of one of the TB preparation was different from other 4 TB samples. The chemical phase and particle size is significantly different for all the 5 TB’s. Pharmacokinetic model confirms difference in various PK parameters such as peak concentration (Cmax), half-life (t1/2) and terminal elimination slope (λz) for all 5 TB’s. TB-A showed highest Cmax (82.21 mg/L), whereas TB-E showed lowest Cmax (48.69 mg/L). The highest bioavailability of TB is may be due to specific chemical moiety and morphology. Based on XRD and elemental analysis, it was found that manufacturing route followed for one of the preparation is not as per ayurvedic text reference. Conclusions: The morphology as well as chemical phase of the five TB’s studied were different from each other, which might be responsible for different pharmacokinetic profiles in Wistar rat model.
Toxicity of Imidacloprid on Peripheral Blood Lymphocytes by MTT Assay and the Ameliorative Effect of Extract of Tinospora cordifolia (Gilloe) Extract
Authors: Khanna Asha , Mukherjee Manoshi , Kachi Muskan , Gautam Daya Shankar , Gokhale Mamta , Aglawe Varsha , Prajapti Ambika
Published: October 2022

Imidacloprid (IMI) is a widely used insecticide which has a specific affinity for insect neonicotinoid acetylcholine receptors. Like all insecticides which are used in excess it tends to bioaccumulate in the environment. So it was thought worthwhile to study its cytotoxicity to human peripheral blood lymphocytes in concentrations ranging from 1.5mM to 4mM after 2 hours and 18 hours exposure by MTT method. Trypan blue test was also used to determine the percentage of living cells. The ameliorative effect of an extract of the stem in water and ethanolic extract of leaves of Tinospora cordifolia (Thunb.) Miers, was also studied. The viability of the lymphocytes showed a fall with increasing concentrations at an exposure of 2 hours. After 18 hours exposure to the IMI only, the viability showed a significant dose dependent drop. Trypan blue test for viability was also conducted. Addition of Tinospora extract raised the viability significantly at 2 hours of incubation. In fact this increase was greatest at 3.5mM and 4mM concentration of drug. The ameliorative effect was maximum at 2 hours. Addition of Tinospora leaf extract showed a significant increase in cell viability at 18 hours of incubation as compared to values obtained with only the drug. Thus a considerable loss of viability of lymphocytes was seen after exposure to the drug in the selected concentrations but herbal extracts seem to help to make the damage less marked. The cells showed a significant rise in viability when incubated with Tinospora leaf extract only, confirming its supportive action in cell proliferation. However, taking into account the evident fall in cell viability caused by exposure to the considerably dilute concentrations tested, caution is needed to prevent over exposure to the pesticide while spraying.
The Effect of Khaya senegalensis on the Endometrial and Vaginal Epithelium: A Histological and Morphometrical Study
Authors: Dani Shalom Chongmel , Attah Martha Orendu Oche , Dibal Nathan Isaac
Published: October 2022

Introduction: Khaya senegalensis is a plant with many medicinal uses and application which could serve as an available and alternative source of medication. It has been used traditionally as an abortifacient agent following folkloric information handed down by word mouth. The aim of this study is to validate this claim by investigating the effect of the extract on the endometrial and vaginal epithelium. Methodology: Four groups of albino rats were administered different dosages of the extract orally and after 28 days, the rats were sacrificed. The micrographs of the uterus and vagina were studied for histologically observations. Morphometric analysis was also carried out to determine the thickness of the epithelial lining in all groups. Measurements were analyzed by one-way ANOVA followed by Dunnett’s multiple comparisons test using GraphPad Prism. Results: Histological observations showed that the extract at a concentration of 50mg/kg and 200mg/kg disrupted the epithelial lining and as the concentrations administered increased, surface and stromal endometrial glands became smaller and sparse and the endometrial stroma became less compact. Morphometric analysis revealed a significant increase of endometrial epithelium in the group administered the least concentration of the extract. Vaginal epithelial thickness was also significantly reduced in all groups. Conclusion: Results obtained suggests that the extract has an anti-fertility effect on the lining of the      uterus and vagina. Further studies are recommended.
Evaluation of Heavy Metals and Microbial Contamination of Selected Herbal Churna Marketed Formulations
Authors: James Vanessa , Panchal Hiral
Published: October 2022

Herbal formulations are popular in India and across the world due to their medicinal properties. Churna is powdered formulations that are consumed widely due to their low cost and ease of administration. Brahmi Churna, Satavari Churna, and Jethimadh churna of 3 different brand manufacturers were procured from the local market. The main objective of the study is the determination of heavy metals and microbiological evaluation as per Ayurvedic Pharmacopoeia. Inductively Coupled Plasma Mass Spectroscopy was performed for the detection of heavy metals. Microbial evaluation was done as per Ayurvedic Pharmacopoeia. The heavy metal content of 7 out of 9 samples complies with the test for heavy metals. Two samples of Shatavari Churna were above the permissible limit of Ayurvedic Pharmacopoeia. The microbial study showed all samples within the allowable limits of Ayurvedic Pharmacopoeia.  Brahmi Churna and Jethimadh Churna were found to be safe for human consumption. Quality checks of Shatavari churna should be performed to ensure the heavy metals are within the permissible limit.
Efficacy of Durvadya Taila and Laghu Manjisthadi Kwatha in Vicharchika (Eczema) in Children
Authors: Merugu Raga Manasa , K C Ragamala , T Prasanna Kumar
Published: October 2022

Vicharchika is a type of Kshudra kustha often encountered by Ayurvedic Pediatric OPDs characterized by symptoms namely Kandu (itching), Srava (discharge), Pidaka (vesicles), and Shyava Varna (discoloration). The involvement of Vata results in dry, blackish lesions of eczema, itching in the affected areas is due to Kapha whereas Pitta is responsible for Srava. Vicharchika has a greater resemblance with Eczema. Ayurveda classics emphasize Shodhana and Shamana therapy as the line of treatment at various places in the management of Kustha. In children Shamana therapy is preferred over Shodhana therapy. So, a clinical study aimed to evaluate the efficacy of Durvadya Taila and Laghu Manjisthadi Kwatha in Vicharchika in children aged 5-16years was conducted considering inclusive and exclusive criteria. Patients were given Durvadya Taila for external application and Laghu Manjisthadi Kwatha internally for 45days twice a day and called for follow up after 15 days of completion of treatment. Among 30 patients, maximum patients were having moderate improvement i.e. 86.67%, 6.67% of patients showed complete remission and 6.67% showed mild improvement. The clinical study clearly concludes that Durvadya Taila and Laghu Manjisthadi Kwatha are safe and effective in the Management of Vicharchika in children.
Effect of core strengthening exercises as an adjunct to stretching exercises on pain and quality of life in females with primary dysmenorrhea: An experimental study
Authors: Kulkarni Neha , Patil Shubhangi
Published: October 2022

Introduction: Primary dysmenorrhea is a common gynecological problem in females, which affects their overall health and quality of life. The objective of the study was to find the effect of core strengthening and stretching exercises on pain and quality of life in females with Primary Dysmenorrhea. Method: Twenty-seven unmarried girls with primary dysmenorrhea, aged between 18 to 25 years were divided into two groups by using simple random sampling i,e Group A (n=14) and Group B (n=13). Group A received core strengthening and stretching exercises and group B received stretching exercises alone, three times a week for 4 weeks. Outcomes measures included in the study were the Numerical Pain Rating Scale (NPRS) and HRQOL SF 36 which was collected at baseline and at week 4 after treatment and follow-ups were taken after 8 weeks. Result: The result showed that all outcome measures improved significantly (p<0.05) in both groups. Significantly more improvement was seen in patients with primary dysmenorrhea who received combined strengthening and stretching exercises. Conclusion: Both the stretching and strengthening exercises are effective in lowering pain and improving the quality of life in females with primary dysmenorrhea but the combination of the two is more effective than stretching exercises alone.
Phyto-pharmacognostical investigation w.s.r. Micrometric investigation of sheethavar seed (Celosia argentea linn.)
Authors: Saraswat Falguni , B Nariya Mukesh , C R Harisha , V J Shukla
Published: October 2022

Celosia argentea Linn. is a leading leafy vegetable of Nigerian country and India. It is herb, ornamental plant which belongs to family Amaranthaceae also having medicinal use in antidiabetic, anti-inflammatory, antioxidant, anti-bacterial, antiapoptosis etc. For proper methodical evaluation, authentication, macroscopy, microscopy, physicochemical parameters, phytochemical screening and qualitative of seed of C. Argentea has been observed under standard approach. The morphological study showed small black shining spherical, lenticular 3mm in diameter, greyish black in color, slightly aromatic in odour and gritty in touch. Microscopical transverse section of cock’s comb seed showed outer layer of epidermis consisting radially elongated rectangular dark brown color cell, narrow collapsed celled band, outer epidermis of tegmen, followed by parenchyma zone with angular cells of perisperm loaded by starch grains and crystals. Cock’s comb inner cell consists of prismatic crystals and aleurone grains. The unplumbed physicochemical parameters and qualitative screening of seed of cock’s comb are as per standard procedure and useful for future analysis.
The Effect of Parent Education on the Extent of Paternal Adaptation in First-Time Fathers
Authors: Mohammad Alipour Monir , Ouzjan kaser Naslihan , Eskandari Narges , Mohammad Alipour Reza
Published: October 2022

Entering the stage of parenthood can be a stressful time and can significantly affect the mental health and well-being of parents by causing lifestyle changes. Thus, this research was created with the aim of assessing the effect of parent education on the extent of depression in fathers, after their first experience with parenthood. Members of the experimental group included 100 husbands of pregnant women visiting Ardebil’s healthcare medical centers, who received counseling and training about accepting the role of fatherhood. Members of the control group included 100 husbands of pregnant women in the same centers, who received the usual pregnancy care. The analysis of the data was conducted on two descriptive and deductive levels. The Kolmogorov-Smirnov test was done to evaluate the normality of the data, and the Mann-Whitney U non-parametric test and the Wilcoxon Signed-Rank test were used for comparing the experimental group and the control group. The findings of the present study showed that the average paternal adaptation score of the control and experimental groups does not have a statistically significant difference before and after the experimental interference. However, the average paternal adaptation score of the experimental and control groups had a statistically significant difference after the experimental interference. Therefore, it can be concluded that education increases paternal adaptation and quality of life. The outcome of this study showed that education and increasing personal information, especially during the childbearing period, increases the quality of life and paternal adaptation.
Verbena officinalis (Verbenaceae): Pharmacology, Toxicology and role in female health
Authors: Mohini Kuchekar , Mohini Upadhye , Amrita Kulkarni , Aishwarya Zambare , Disha Shirke , Padmaja Kore
Published: October 2022

Verbena officinalis Linn (Verbenaceae), the common verbena or vervain, a traditional herb with immense cultural and medicinal significance in the European, Greek, American, Roman and Egyptian countries. Phytochemical analysis suggests the presence of iridoid glycosides, secoiridoid glycosides, phenylethanoid glycosides, flavones, pentacyclic triterpenoids, monoterpenes, sterols and their derivatives. Owing to the presence of these phytochemicals, wide range of pharmacological activities such as antibacterial, antiviral, antifungal, antidiarrheal, antitumour, antidepressant, anxiolytic, gastroprotective and hepatoprotective, etc are reported. Literature survey highlights the distinct role of Verbena officinalis in treating dysmenorrhoea, vaginitis, endometriosis, premenopausal night sweating, herbal tonic for pregnant women and lactating mothers and its use as emmenagogue. The review aims to promote studies on Verbena officinalis for its therapeutic role in female reproductive health and other ailments. The scientific databases used for compilation of the data were Google scholar, Pubmed the data made available specifically from 2010 to 2022.
Sida Acuta Burm. fil. : Potential benefits
Authors: Kaur Amanpreet , Singh Rattan Deep
Published: October 2022

For masses of years, flora and herbs had been an amazing supply of meals and medication. Surveys performed in indigenous locations discovered that the Sida acuta had many regional conventional usages. This broom weed is a perennial plant that produces slightly woody stems and is harvested from the wild as a source of local medicine and fiber. In tropical countries, indigenous people used this plant to treat common illnesses which include fever, headache, and various infections. Scientifically, Sida acuta has already been studied for several potential benefits. Studies reveal that roots of Sida acuta can be chewed to relieve toothache and leaves are soaked in water to make hair conditioner or shampoo to treat scaly skin. Apart from these benefits, it is also being known for repressing the potential of parthenium (poisonous herb) species through an allopathic control over it. . This review article mainly focuses on therapeutic applications of Sida acuta and in addition, its components, advanced usages, bioactive compounds, and essential micronutrients are also discussed.
Analytical standardization of Shleshmantaka Agad
Authors: Chalakh Sonali , Wanjari Anita , Wadnerwar Nilima
Published: October 2022

Background:  To counter-act the action of visa,(poison) ancient Acharyas have mentioned the different types of Agada. Though Acharyas have mentioned various types of potent Agadas in various poisoning conditions, still these Agadas have neither undergone analytical study nor animal experiment. Shleshmantaka  Agad is one of the drug remedy mentioned in Shushrut Samhita, kalpa sthan  used for treatment of snake bite poisoning. Aim: In present work an attempt has been made to standardize Shleshmantaka Agad. Material & Methods: Physicochemical parameter was tested by Loss on drying, Acid insoluble Ash, Total ash value, Water & Alcohol soluble Extractive Value, HPTLC was used for phytochemical analysis. Result: In analytical study of Shleshmantaka Agad obtained value of Loss on drying, Total ash value, Acid insoluble Ash ,Water & Alcohol soluble Extractive Value are 12%, 10%, 2%, 13%, 1% respectively and in HPLC major constitute phytoamines  was detected. Conclusion: Analytical findings   of present study can be considered as reference standard for SA. As Shleshmantaka Agada is a combination of many phyto-constitutes but major constituent are phytoamines which may be possesses anti-snake venom property.
A Comparative Study on the efficacy of Tryushanadi Vati with and without Pathya in children suffering from Pratishyaya (~Allergic Rhinitis)
Authors: Rathi Renu B , Gulhane Amit , Rathi Bharat
Published: October 2022

Background: Pratishyaya is one of the most common disorders in the pediatric age group. The accumulated Vatadi doshas get to reside in the nose and produce various types of discharges from it which is called Pratishyaya. Pratishyaya is discussed under the 31 Nasagataroga by Acharya Sushruta. It is a disease of KaphaVata dominance characterized by Nasasrava (Nasal discharge), Nasanaha (Nasal Congestion), Shirogourava (Heaviness), Anadhvapihita Nasa (Intermittent nasal Obstruction) and is difficult to cure. Aim: To study the effect of Tryushanadi vati in Pratishyaya. Material & Method: 30 children were randomly selected according to a computer-generated randomized chart and assigned to two groups. In which Tryushanadi Vati and Tryushanadi Vati with Pathya were given according to the age group of 7 days. The results are then interpreted and analyzed statistically. Results: There was a significant improvement in Nasasrava, Nasanaha, Kshwathu (sneezing), and Klama (fatigue). It is the treatment principle that is effective in the Sampraptivighatan (breaking the pathogenesis) of Pratishyaya resulting in the alleviation of features. The overall result after treatment by statistical analysis was 46.87 % in the group of T vati and 57.51% in T vati+P. Statistically, both the groups T vati and T vati +P have shown significant results as per subjective and objective criteria but T vati+P has more efficacy owing to the synergistic effect of Pathya.
A study on the role of matravasti in Hirschsprung disease in children
Authors: Balakrishnan Deepthi , Rathi Renu
Published: October 2022

Hirschsprung disease (HSCR), or congenital intestinal aganglionosis, is a birth defect characterized by the complete absence of neuronal ganglion cells from a portion of the intestinal tract. Symptoms include constipation, bloating of the belly, and loss of energy and appetite. Diagnosis of the disease includes an abdominal x-ray which shows a bulge in the large intestine caused by stool, barium enema, anorectal manometry, or biopsy of the rectum.  In Ayurveda, congenital diseases come under janmabala pravritta vyadhi. It leads to vitiation of the rasavaha, annavaha and malavaha srothas of the fetus, later leading to dusti of vata in pakwashaya and guda. The treatment involves normalization of Vata in the body using a protocol that pacifies the Vata, including Vasti. Considering the age of the patient, Matravasti was done using Sukumaraerandam and a few internal medicines for the mother. It consists of drugs that pacify Vata as well as those which improve digestion.
A comparative analytical study of Ashodhit and Shodhit roots of Thevetia neriifolia Juss. W.S.R Yogratnakar
Authors: Urkude Minakshi , Chalakh Sonali , Pargaonkar Akshay , Bangare Priyanka
Published: October 2022

Background: In Ayurveda whenever poisonous drugs (Visha Dravya) used as a part of medicine, they need purification (Shodhana) before therapeutic use. Peet Karveer (Thevetia neriifolia Juss.) is a cardiac poison which contains mainly cardiac glycosides like Cerberin, Nerifolin, Thevetin A and B, Peruvoside, Ruvoside. If the toxic components are removed then Thevetia neriifolia Juss is a good source of medicine in many Ayurvedic formulations as an ingredient. Aim and Objectives: The aim of the present study was to compare various physicochemical parameters and HPLC analysis of Shodhit and Ashodhit Thevetia neriifolia Juss root with special reference to Yogratnakar. Material and Method: One part of Thevetia neriifolia Juss roots were pounded and made fine powder as Sample A and another part of Thevetia neriifolia Juss roots were subjected for boiling (Swedan) procedure in cow’s milk for 3 hours and made fine powder as Sample B. And studied the physicochemical and phytochemical analysis by HPLC. Result: After purification, different physicochemical parameters and phytochemical analysis which were performed using generally accepted laboratory technique, it was found that there was change in their values. Conclusion: The present study was reflected the importance of Shodhana (purification) method of the Thevetia neriifolia Juss roots (the toxic drug) which shows the reduction of toxic constituents.
An Ayurvedic Management of Paroxysmal Supraventricular Tachycardia
Authors: Kumbhar Prakash , Kore Naresh , Chouvan Smita
Published: October 2022

Background: Paroxysmal Supraventricular Tachycardia is a type of Supraventricular tachycardia (SVT) and is defined as intermittent SVT and typically presents with a ventricular rhythm of 160 bpm. The patient morbidity with paroxysmal supraventricular tachycardia (PSVT) is directly proportional to the frequency of episodes, and it can be life-threatening in patients with atrial fibrillation and ventricular pre-excitation. Its management depends and varies according to severity of the symptoms which includes long-term treatment to surgical procedure like catheter ablation. Case Report: A 26-year Female patient, who was a known case PSVT, approached with complaints of recurrent palpitations, chest discomfort with breathing difficulty, palpitation, lightheadedness and exercise intolerance. Conclusion: the patient was diagnosed as vataja hridaroga and treated with ayurvedic medicine for the duration of 3-4 months. With the help of ayurvedic medicines, patient is free from symptoms and chronic drug therapy.
Management of primary infertility with multifactor etiology - A case report
Authors: Tanaji Patil Rupali , Vishala Turlapati
Published: October 2022

In this case study patient aged 27 years presented with anxious to conceive since two years of regular and satisfactory marital relationship seeking Ayurvedic line of treatment, diagnosed with unexplained hyperprolactinemia & hyperemic cervix. From detailed history involvement of vitiated Vata and kapha, Agnimandhya noticed. she was treated with samshamani vati and kapikacchu churna orally along with panchavalkal taila yonipichu. With above mentioned medications patient approached with history of missed period and when advised for Urine Pregnancy test and was found to be positive Followed by dating scan confirmed the intrauterine pregnancy. An attempt is made in this article to analyze the probable cause of her infertility and management strategy adopted.
Determination of Total phenolic content and Antiurolithiatic activity of Sahasravatamulika (Hibiscus cannabinus Linn.) Extract and Fractions
Authors: Wali Sneha , Patil Sneha B , Patil Mrityunjaya B
Published: October 2022

The purpose of this study was to assess the total phenol content and invitro antiurolithiatic activity of Hibiscus cannabinus extract and various fractions. Kidney stones are one of the most painful and prevalent urinary tract disorders. Drug treatment and Extracorporeal Shock Wave Lithotripsy (ESWL) are used to treat kidney stones. Instead of dissolving the stone, these treatments may cause acute renal damage and an increase in stone production. Phenolic compounds show the best stone dissolution rate, i.e., they could dissolve calcium oxalate stones. In the present research Hibiscus cannabinus phenolic fraction was tested for its capacity to dissolve calcium phosphate stones, which is one of the many forms of kidney stones that can form. The highest phenolic content was found in the Ethyl acetate fraction of the plant, which was assessed using Gallic acid as a standard. This fraction was then tested for Antiurolithiatic activity in an in-vitro manner employing the egg's semipermeable membrane. The fraction can be evaluated for additional in-vivo and in-vitro investigations to determine its ability to dissolve Kidney stones developed in humans.
The Influence of CSR, Environmental Awareness and Audit Committee Quality on Company Earnings Quality
Authors: Amelya Amelya , Nazar Shinta Ningtiyas
Published: October 2022

This study aims to examine the effect of Corporate Social Responsibility (CSR), environmental awareness and audit committee quality on earnings quality. The research methods used are quantitative research methods and associative methods. The population in this study is the Sri Kehati Index company listed on the Indonesia Stock Exchange for the 2016-2020 research period, totaling 25 companies, from the total population a purposive sampling technique is used with several criteria to determine the sample, so that a sample of 8 companies is obtained. The data analysis technique used in this study uses eviews10 which includes descriptive statistical tests, panel data model analysis, classical assumption tests and hypothesis testing. The results of this study indicate that partially corporate social responsibility (CSR) is considered to have an effect on the Earning Quality of Sri Kehati Index companies listed on the Indonesia Stock Exchange for the 2016-2020 period, while environmental awareness and audit committee quality are considered to have no effect on the Earnings Quality of Sri Kehati Index companies. Sri Kehati listed on the Indonesia Stock Exchange for the period 2016-2020. The results of this study also show that simultaneously the three independent variables, namely Corporate Social Responsibility (CSR), Environmental Awareness and the Audit Committee, do not have a significant influence on the dependent variable of Earnings Quality.
INVESTMENT OPPORTUNITY SET AND CORPORATE SOCIAL RESPONSIBILITY ON COMPANY VALUE
Authors: Kusuma Adelia Kintan , Hariyani Diyah Santi , Sulistyowati Liliek Nur
Published: October 2022

The purpose of this study was to determine the effect of investment opportunity set and corporate social responsibility on firm value. This research is a type of secondary data quantitative research. The population used in this study is the infrastructure companies listed on the IDX. The sampling technique used was purposive sampling, in order to obtain 15 infrastructure companies over a 5-year period which were used as research samples. The data collection method is done by accessing the annual reports listed on the IDX and published by each infrastructure company on their respective websites. The data obtained is then processed with the help of SPSS 21 software. The results of this study indicate that the investment opportunity set affects firm value. Corporate social responsibility has no effect on firm value.
Influence Of Corporate Social Responsibility, Profitability, Capital Structure On Company Value
Authors: Alfiadin Ardian , Susilo Dwi Ermayanti
Published: October 2022

This study aims to determine the effect of Corporate Social Responsibility, Profitability, and Capital Structure on Company Value in the current Covid 19 pandemic era. The problem sttement in this study are as follows: 1) Does Corporate Social Responsibility (CSR) have a positive effect on Pharmaceutical Companies Value registered on IDX for the period 2017-2021, 2. Does profotability has positife influence to Pharmaceutical  Companies value registered on BEI on periode 2017-2021, 3) Does Capital Structure have a positive effect on Pharmaceutical Companies Value registered on IDX for the period 2017-2021, 4) Does Corporate Social Responsibility (CSR), Profitability, and Capital Structure have a positive effect on Company Value in Pharmaceutical companies registered on IDX for the period 2017-2021.This research uses descriptive quantitative research. The population and sample in this study are pharmaceutical companies listed on the Indonesia Stock Exchange for the period 2017-2021. The data used is secondary data on annual financial reports on the Indonesia Stock Exchange. This study uses data analysis techniques such as multiple regression analysis and SPSS as a tool to process and test data. The results of this study indicate that partially CSR has no significant effect, ROE has a significant effect and DER has no significant effect on firm value. Meanwhile, simultaneously CSR, ROE, and DER have a significant effect on firm value.
Phosphorus Forms and Fixing Potentials of Mbaitoli Soils in Imo State, Nigeria
Authors: Igbozuruike Christopher Ifeanyi
Published: October 2022

The study was conducted in four different locations in Mbaitoli namely; Ifakala, Umunoha, Ogwa and Orodo in Imo State Nigeria to determine different forms and levels of phosphorus in the selected soils of the area. Fifteen composite samples were collected from the top soil (0-15cm) and sub soil (15-30cm). The fifteen composite soil samples were then bulked and a sample taken from each of the location giving a total of four representative samples. The representative soils were analyzed for physical and chemical properties. Total and Organic phosphorus were determined by standard laboratory procedure while inorganic phosphorus forms by fractionation. The macronutrients Nitrogen (N) and Potassium (K) were high low (0.220 % and 0.23mg/kg) and the pH is acidic (4.50). Available phosphorus ranged from 42.70 to 48.50 mg/kg with a mean of 46.25mg/kg while the organic phosphorus content ranged from 42.17 to 46.62mg/kg with a mean of 44.49mg/kg, total phosphorus content ranged from 102.7 to 113.71mg/kg with a mean of 108.48mg/kg. Total phosphorus and available phosphorus were very high in the soil of the study area and were in the following order; Fe-P>Al-P>Ca-P>occluded phosphorus.
Cigarette Smoking: The Perceptions of Islamic Religious Leaders in the Province of Tawi-Tawi, Philippines
Authors: A. Sali Najeeb Razul
Published: October 2022

Cigarette smoking is a day-to-day practice of some Muslims, particularly in the province of Tawi-Tawi. The issue of the specific legal rule on cigarette smoking is controversial and debatable among Muslim scholars. This study shows qualitative and quantitative results on the perceptions of Muslim religious leaders on cigarette smoking in Tawi-Tawi. The key-informant interview of this study finds that cigarette smoking is haram following verses from Qur’an, 4:29, 2:195, 17:26-27; and hadith: “there should be neither harming nor reciprocating harm.”Although few regarded it as makruh, the Binary Logistic Regression Analysis test result shows that age has a negative correlation with the chance of haram responding to smoking. At the same time, female respondents indicate consistency in responding to haram compared to their male counterparts. Educational attainment shows positively correlated with haram as ruling for cigarette smoking. This study concludes that cigarette smoking is haram from the Islamic perspective
Community Engagement: Perceptions and Responses to COVID-19 Risk Communication among Rural Dwellers in Enugu State
Authors: E Udeze Prof. Sunny , Ezinwa Dr. Chidiebere Anthony , Okwudiri Dr. Ekwe
Published: October 2022

This study investigates the perceptions and responses to Covid-19 risk communication among rural dwellers in Enugu State. In conducting this study, survey research method was used to generate quantitative and qualitative data from rural residents in select communities in Enugu State through the instrumentality of questionnaire and Key Informant Interview. A sample size of 384 was drawn from the population using Wimmer and Dominick online sample calculator. Analysis of data generated revealed that the most reliable source of health messages on Covid-19 for rural residents during the pandemic was the radio. More so, majority (52 percent) of the sampled respondents were of the view that they had a moderate knowledge about Covid-19 controlling and preventive measures and majority of the respondents practiced Covid-19 preventive measures to a moderate extent. Religious and cultural norms were found to be major barriers to Covid-19 messages targeted at rural people. Based on the findings, it was recommended that health messages targeted at rural residents should take into account some factors that are peculiar to rural environment such as religious and cultural issues, poverty, level of education and access to adequate information.
ESTRATÉGIAS DE NOTIFICAÇÃO E TRATATIVAS DOS INCIDENTES RELACIONADOS ÀS METAS DE SEGURANÇA DO PACIENTE: PROTOCOLO DE REVISÃO DE ESCOPO
Authors: Silva Maria da Conceição Nunes da , Jorge Maria Salete Bessa , Carmo Furtado Cora Franklina do
Published: October 2022

Trata-se de um protocolo de revisão de escopo sobre as estratégias de notificações e tratativas dos incidentes relacionados às metas de segurança do paciente. Tem como objetivo documentar  os  processos envolvidos no planejamento e condução metodológica de uma revisão de escopo, objetivando  diminuir  vieses  na busca e seleção de referências, tornando claros e uniformes esses critérios entre os revisores. A revisão será orientada pelas diretrizes do Manual Joanna  Briggs  Institute  (JBI) e utilizará estratégia de busca detalhada e individual em ao menos três bases de dados para cada base de dados. O processo  de  seleção  e  extração  de  dados  se  dará  pela  avaliação  de  dois  revisores  atuando independentemente. O protocolo  da  revisão  foi  elaborado  seguindo  os  itens  do  PRISMA  Extension  for Scoping Reviews (PRISMA-ScR).
O CAPITALISMO EXCLUDENTE COMO CORROBORADOR DA OBESIDADE: O SERVIÇO SOCIAL COMO INSTRUMENTO NA BUSCA DE DIREITOS
Authors: Binda Dório , Assunção da Cunha Amanda
Published: October 2022

Resgata-se na história fatores que corroboram para o desenvolvimento da obesidade, e o papel do Serviço Social na construção de políticas públicas, assim como a luta contra o capitalismo excludente que favorece o adoecimento populacional. A falta de informação e pertencimento das pessoas, fatores sociais, psicológicos e econômicos contribuíram, ao longo dos anos, para o desenvolvimento da obesidade. Considerando estes aspectos que norteiam a problemática, o objetivo central desse estudo visou a compreensão, dentro do percurso histórico brasileiro, na composição social, sob a perspectiva do capitalismo, os problemas relacionados à obesidade. Metodologicamente este estudo trata-se de uma abordagem qualitativa a partir de uma busca bibliográfica nas bases de dados. Como resultados e considerações ressalta-se que o problema da obesidade é uma questão que envolve história e cultura, neste contexto, o serviço social entra como apoiador na resolução da problemática e na garantia dos direitos constitucionais.
INDUSTRIJALIZACIJA GRADA OSIJEKA, POSEBAN OSVRT NA PRVE DVIJE FAZE INDUSTRIJSKOGA RAZVOJA
Authors: Penava Brekalo Zvjezdana
Published: October 2022

U drugoj polovici devetnaestoga i početkom dvadesetoga stoljeća
Osijek je bio drugi grad u Hrvatskoj po demografskim pokazateljima i gospodarskim potencijalima. U navedenome razdoblju
otvoreno je nekoliko vrlo respektabilnih, među najvećim gospodarskim subjektima na hrvatskome nacionalnom prostoru pivovara i tvornica žigica, tvornica kože, plinara, tvornica namještaja,
tvornica lana, tvornica šećera, tvornica čokolade, tvornica sapuna, tvornica keksa i dr. gospodarskih subjekata. Autorica u radu
na temelju arhivskoga gradiva i relevantne literature prikazuje
industrijalizaciju grada Osijeka tijekom prvih dviju faza industrijskoga razvoja, i to obrtno-manufakturnu od 1853. do 1870. i
željezničku fazu od 1870. do 1918. godine, pri čemu je istaknula
značenje grada na Dravi kao ekonomskoga središta Slavonije i
cijele istočne Hrvatske.
Ključne riječi: grad Osijek; tranzicija; industrija; industrijski
razvoj.
HOW MUCH DOES NEGATIVE LIBERTY NEED POSITIVE LIBERTY IN ECONOMIC ISSUES?
Authors: Perić Zdravko , Petković Marin
Published: October 2022

In attempting to rectify the inequalities ensuing from the flaws of
negative liberty, proponents of social justice turn to economic policies based on positive liberty. Unaware of the value provided by
each of these notions of liberty, they neglect the tyrannical potential
of positive liberty which results from its instrumental value. Promoting government intervention in the market and redistribution
of resources as a means by which inequalities are to be redressed,
allows for the concentration of power in one place, which renders
individual freedom ineffective. This paper suggests that the promotion of social justice through positive liberation is damaging to individual freedom due to the government’s monopoly on regulating
the social structure.
Keywords: social justice; negative liberty; positive liberty; equality; paternalism; economic freedom
“Is happiness mere technique”?
Authors: Kapustin Petr , Zadvoryanskaya Tatyana
Published: October 2022

Architecture has not served consumption for millennia; the “functions” it fulfilled were rather nominal: it was not the function but the mission that prevailed. A mission to organize the afterlife. The fact that all cultures considered burial as a way to eternal and blissful life contributed little to the happiness of the living derived from architecture. The problem of organizing happiness is very “young” in architecture. And it still raises more questions than ready answers. However, this problem uncovers the layers of architectural consciousness and tradition which are difficult or impossible to uncover otherwise.
Manufacturing and the spatial transformation of the city
Authors: Engel Barbara , Kozlov Valery , Gulyaeva Ksenia
Published: October 2022

The article considers a design solution for the spatial transformation of the city of Heidelberg, Weststadt district, using the method of synchronized typologies in the conditions of a former industrial area, as well as a proposal for a new production system for the area.
Modern market housing and deprivation of happiness
Authors: Anisimova Lyudmila
Published: October 2022

On the example of modern development of multi-apartment residential complexes, the article studies the quality parameters of the living environment depending on the planning characteristics of the apartments, the number of rooms in the apartment and the percentage ratio of small-sized one-room apartments and studios in relation to multi-room apartments in the complex. Negative characteristics of the layout of apartments are identified on the basis of the POE (post-occupancy evaluation) concept. Taking into account the efficiency coefficient of apartments, the most optimal layout options are determined. The article studies the qualitative parameters of the residential environment associated with a certain degree of risks. It analyses and proposes the parameters of the optimal percentage ratio of different types of apartments in the complex for the formation of a sustainable housing system.
The road to home
Authors: Rappaport Alexander
Published: October 2022

On the example of the manor created by Totan Kuzembaev in Latvia, the author develops an analysis of the categories and archetypes fundamental to architecture: space, style, border, substance, time and home. The understanding of the meaning of one’s home is synchronous with the understanding of oneself. In the context of the analysis, the author considers the concept of the border among settled and nomadic peoples, who today exist in close connection. Their metamorphoses are revealed in the understanding of the wall and window, the cult of Heaven, the images of Paradise and Utopia. The ring enclosing the Self and the Other, East and West, is revealed in love as real and true. The author problematizes the search for architectural style, the meaning of home as a way of life in the new millennium, mastering the possibilities of free individuality.
Eco-development of territories allocated for low-rise residential buildings
Authors: Bazhenova Elena , Bazhenov Alexander
Published: October 2022

This article discusses the ecological principles of creating sustainable prototypes and models in order to define architectural and spatial features of territories allocated for low-rise residential buildings as the basis for the eco-development of suburban spaces. It also describes its stages, where the introduction of digital technologies can provide effective management of the development of territories from an urban and environmental point of view.
Photocatalytic Degradation of Phenol in Wastewater: A Mini Review
Authors: A.I. Lawal , Z. Muhammad , C.V. Obunadike , Y.Y. Yakubu , A.O. Ogunsanmi , O.O. Olabode , C.O. Ayodele , F.E. Komolafe
Published: October 2022

A major public health concern in many developing countries, including Nigeria, is the quality of their water supply. Everything a live entity does depends on water, a fundamental component of the biosphere. To ensure that water is safe for industrial and home use, it must be treated before consumption. However, phenolic compounds are found in our water bodies due to the polluted wastewater from industrial, agricultural, and home activities. Nature also has a role in their occurrence. These substances are poisonous and can cause long-term harm to both humans and animals. This paper reviewed research on the photodegradation of phenol utilizing nanoparticles in water treatment. This provides additional information and facts on cost-effective methods of treating wastewater and mineralizing phenol into valuable chemicals.
The Role Of Religious Morals On Students' Academic Cheating Behavior During Online Learning During The Covic-19 Period
Authors: Ariani Meiliyah , Ismi Islami Dian
Published: October 2022

Cheating behavior is a dishonest act carried out by someone in order to get a satisfactory end result. Academic cheating is still often done by students, to get high grades. The emergence of a feeling of worry or feeling threatened that is felt because of the inability or less than optimal of a student in completing his college assignments triggers students to commit academic fraud due to various demands from the environment that expect high results and grades. This study aims to determine the effect of academic integrity factors and religious moral factors on student academic cheating during online learning during the Covid-19 period at Prof. University. Dr. Moestopo (Religious) Academic Year 2021-2022 even.The sample method used is purposive sampling. The number of students who were sampled in this study were 350 students of Prof. University. Dr. Moestopo (Religious), Even Semester. The data used is primary data in the form of questionnaires distributed to respondents using google form facilities. This analysis method uses descriptive statistical tests, data quality tests, classical assumption tests, data analysis tests and model suitability tests using the SPSS program.The results showed that religious moral factors and academic integrity had a significant effect on students' academic cheating behavior. Partially, this study shows that religious moral factors have a negative and significant effect, while academic integrity factors have a positive and significant effect on academic cheating behavior in the online learning system.
Treatment and prognosis of elderly patients with unruptured cerebral aneurysms
Authors: Kim Ji Hong , Kang Dong Ho , Lee Chul Hee , Park In Sung , Hwang Soo Hyun , Lee Ja Myoung
Published: October 2022

Objective: In recent years, the number of cases of unruptured intracranial aneurysms in older patients has been increasing, but the best treatment remains a matter of debate. This study aimed to compare the treatment methods for unruptured intracranial aneurysms in patients aged 65 years and older.Methods: A retrospective review was conducted of data from unruptured intracranial aneurysms treated with surgical clipping or endovascular coiling between 2004 and 2019. Clinical and imaging information was collected. The treatment methods, procedure-related complications, and imaging and clinical results were analyzed. Data were assessed through a comparative analysis of underlying diseases (diabetes mellitus, hypertension, and hypercholesterolemia), smoking and alcohol use history, the location and size of the aneurysms for patients who received each treatment, and complications that occurred after each treatment.Results: Of 211 patients over the age of 65, 71 were treated with clipping and 140 with coiling. The complications that occurred immediately after treatment included postoperative hemorrhage (subarachnoid hemorrhage, intracerebral hemorrhage, intraventricular hemorrhage), chronic subdural hemorrhage, infection, and puncture site infection. Postoperative computed tomography images of the clipping sites had four times more opacity than those of coil embolization, but the outcomes (Glasgow outcome scores) showed no significant differences between clipping and coil embolization.Conclusion: Coil embolization and clipping are safe and effective treatment methods for unruptured intracranial aneurysms in elderly patients. Thus, the active treatment of unruptured intracranial aneurysms, which are likely to be retrofitted, should be considered.