bluuebunny/crossref_metadata_2025 huggingface dataset:
IDENTIFICATION OF A TIME-DEPENDENT SOURCE TERM IN A NONLOCAL PROBLEM FOR TIME FRACTIONAL DIFFUSION EQUATION
Authors: Ismailov Mansur I. , Çiçek Muhammed
Published: March 2024

This paper is concerned with the inverse problem of recovering the time dependent source term in a time fractional diffusion equation, in the case of nonlocal boundary condition and integral overdetermination condition. The boundary conditions of this problem are regular but not strongly regular. The existence and uniqueness of the solution are established by applying generalized Fourier method based on the expansion in terms of root functions of a spectral problem, weakly singular Volterra integral equation and fractional type Gronwall’s inequality. Moreover, we show its continuous dependence on the data.
A DISCRETE VERSION OF THE MISHOU THEOREM RELATED TO PERIODIC ZETA-FUNCTIONS
Authors: Balčiūnas Aidas , Jasas Mindaugas , Rimkevičienė Audronė
Published: March 2024

In the paper, we consider simultaneous approximation of a pair of analytic functions by discrete shifts $\zeta_{u_N}(s+ikh_1; \ga)$ and $\zeta_{u_N}(s+ikh_2, \alpha; \gb)$ of the absolutely convergent Dirichlet series connected to the periodic zeta-function with multiplicative sequence $\ga$, and the periodic Hurwitz zeta-function, respectively. We suppose that $u_N\to\infty$ and $u_N\ll N^2$ as $N\to\infty$, and the set $\{(h_1\log p:\! p\in\! \PP), (h_2\log(m+\alpha): m\in \NN_0), 2\pi\}$ is linearly independent over $\QQ$.
Improving Photometric Redshift Estimation for Cosmology with LSST Using Bayesian Neural Networks
Authors: Jones Evan , Do Tuan , Boscoe Bernie , Singal Jack , Wan Yujie , Nguyen Zooey
Published: March 2024

We present results exploring the role that probabilistic deep learning models can play in cosmology from large-scale astronomical surveys through photometric redshift (photo-z) estimation. Photo-z uncertainty estimates are critical for the science goals of upcoming large-scale surveys such as the Legacy Survey of Space and Time (LSST); however, common machine learning methods typically provide only point estimates and lack uncertainties on predictions. We turn to Bayesian neural networks (BNNs) as a promising way to provide accurate predictions of redshift values with uncertainty estimates. We have compiled a galaxy data set from the Hyper Suprime-Cam Survey with grizy photometry, which is designed to be a smaller-scale version of large surveys like LSST. We use this data set to investigate the performance of a neural network and a probabilistic BNN for photo-z estimation and evaluate their performance with respect to LSST photo-z science requirements. We also examine the utility of photo-z uncertainties as a means to reduce catastrophic outlier estimates. The BNN outputs the estimate in the form of a Gaussian probability distribution. We use the mean and standard deviation as the redshift estimate and uncertainty. We find that the BNN can produce accurate uncertainties. Using a coverage test, we find excellent agreement with expectation—67.2% of galaxies between 0 < 2.5 have 1σ uncertainties that cover the spectroscopic value. We also include a comparison to alternative machine learning models using the same data. We find the BNN meets two out of three of the LSST photo-z science requirements in the range 0 < z < 2.5.
Postperihelion Cometary Activity on the Outer Main-belt Asteroid 2005 XR132
Authors: Cheng 鄭 Yu-Chi 宇棋 , Bolin Bryce T. , Kelley Michael S. P. , Bodewits D. , Ye 葉 Quanzhi 泉志 , Fremling Christoffer , Lin 林 Zhong-Yi 忠義 , Wu 吳 Ya-Lin 亞霖 , Riddle Reed L. , Ip 葉 Wing-Huen 永烜 , Groom Steven L. , Laher 良主 Russ R. 嶺亞
Published: March 2024

We report comet-like activity on the outer main-belt asteroid 2005 XR132 discovered by the Lulin One-meter Telescope in early 2021 April. A series of follow-up observations were triggered to characterize the morphology and brightness variation of 2005 XR132. Long-term photometric data of the 2020 perihelion return reveal a 2 mag fading in 120 days, starting 20 days postperihelion, attributed to decreased cometary activity. Even though no variation indicative of the rotational period can be found in our data, we infer an a/b axial ratio of 1.32, given that the lower limit of rotational amplitude is 0.3 mag. A visible spectrum and broadband color support that 2005 XR132 has a reflectance feature similar to a BR-type Centaur object. The syndyne and synchrone simulations reveal a low-speed dust ejecta consisting of millimeter-sized dust grains released shortly after the perihelion passage. We demonstrate that 2005 XR132 has a short dynamical lifetime of 0.12 Myr, with <5% of it in the near-Earth space. Due to the strong gravitational influence from Jupiter and Saturn, the asteroid has followed a random walk orbital migrating process. We also find that since 1550 CE, the perihelion distance of 2005 XR132 has gradually decreased from 2.8 to 2.0 au, likely due to the Kozai–Lidov effect, which potentially reactivated the dormant nucleus. All these dynamical properties support a cometary origin for 2005 XR132 rather than an ice-rich main-belt object kicked out from a stable orbit, although current observational evidence has yet to confirm repeating cometary activities.
Redescription of Apanteles mimoristae (Hymenoptera, Braconidae), a parasitoid of the native pyralid cactus moth Melitara cf. nephelepasa in central Mexico
Authors: Villegas-Luján Renato , Plowes Robert , Gilbert Lawrence E. , Rodríguez Julio Cesar , Canales-del-Castillo Ricardo , Gallegos-Morales Gabriel , España-Luna Martha P. , Fernández-Triana José , Sanchez-Peña Sergio R.
Published: March 2024

Novel trophic associations have sometimes resulted in fortuitous and significant biological control. After the invasion of North America by the South American cactus moth, Cactoblastis cactorum (Berg) (Pyralidae: Phycitinae), it is pertinent to characterize the assemblage of local natural enemies that could utilize this moth in new host-parasitoid associations. Herein we report on Apanteles mimoristae Muesebeck (Braconidae: Microgastrinae), a North American gregarious endoparasitoid wasp attacking the caterpillar of the phycitine cactus moth Melitara cf. nephelepasa (Dyar) (Pyralidae: Phycitinae, also known as zebra worm), also native to North America; both collected in Opuntia ficus-indica (L.) Mill. (Cactaceae) cultivated fields at rural areas of Mexico City. We provide an updated morphological account for A. mimoristae visualized with light microscopy and scanning electron microscope (SEM); a fragment of its cytochrome oxidase subunit I (COI) gene sequence data is reported for the first time. Additionally, we analyze its taxonomical position relative to other Apanteles species from the Americas including those attacking cactus-feeding moths. Our analyses place A. mimoristae (from Mexico) in a clade with A. esthercentenoae Fernández-Triana (from Costa Rica), a parasitoid of both Cromarcha stroudagnesia Solis (Pyralidae) and Palpita venatalis (Schaus) (Crambidae) (non cactus-feeding), and in a sister clade to A. opuntiarum Martínez & Berta (from Argentina) and A. alexanderi Brèthes (from Argentina and Uruguay), parasitoids of the cactus-feeding phycitines Cactoblastis and Tucumania respectively. Finally, we provide an updated key for the identification of Apanteles species recorded parasitizing cactus moth caterpillars in the American continent.
Réussite éducative et construction identitaire : une double mission de l’école francophone au Canada
Authors: Cool Jacques
Published: March 2024

Le Canada est connu pour sa diversité culturelle et linguistique, avec le français et l’anglais comme langues officielles. Les compétences en matière d’éducation et de santé relèvent des provinces, ce qui crée des défis pour celles où le français est minoritaire. La double mission de l’école consiste à y promouvoir réussite scolaire et construction identitaire liées à la langue et à la culture francophone, dans un contexte d’assimilation vers l’anglais. Les politiques éducatives provinciales mettent l’accent sur la fierté culturelle et linguistique au sein des communautés acadiennes et francophones très engagées. Les élèves de ces milieux pourront-ils y vivre leur vie en français tout en se réalisant pleinement dans le développement de compétences globales pour le XXI e siècle ?
L’Hexagone et l’Archipel, ou les métamorphoses de l’universel : la place des littératures francophones dans l’enseignement (du) français
Authors: Authier François-Jean
Published: March 2024

La consécration des œuvres littéraires en langue française hors de France a-t-elle jusqu’à présent emprunté la voie solennelle et majestueuse des programmes scolaires ? L’école constitue l’une des modalités de dignification et de labellisation d’une production littéraire. Donc il semble essentiel de vérifier si le processus de panthéonisation s’est porté de manière significative sur des textes issus des différentes aires francophones. La question de la reconnaissance de la valeur intrinsèque de l’œuvre en constitue les prémisses. Le versant pédagogique de l’histoire littéraire montre combien les programmes scolaires ont privilégié jusqu’aux années 1980 la patrimonialisation hexagonale, au détriment d’œuvres éparses et archipélisées. La stabilité longtemps passéiste et aujourd’hui beaucoup plus ouverte des programmes de lettres ne saurait suffire : une véritable révolution copernicienne se révèle nécessaire afin d’inverser la tendance et de promouvoir dans le français qu’on enseigne dans l’Hexagone à la fois l’Ailleurs et l’Autre de notre langue commune.
Les programmes d’histoire : marges, silences et enjeux
Authors: Legris Patricia
Published: March 2024

Textes officiels à caractère national et obligatoire, les programmes d’histoire remplissent plusieurs fonctions : culturelle, mémorielle, civique notamment. Cette dernière est fondamentale pour la discipline chargée dès lors de transmettre aux élèves une citoyenneté centrée sur la Nation à travers un récit historique qui se déroule essentiellement en France métropolitaine. L’imposition de cette narration, acceptée et intériorisée jusque dans les années 1970 dans des territoires éloignés du centre, est désormais contestée et invite à une réflexion sur la pluralité au sein de la Nation française tant au niveau linguistique qu’historique, tout comme à une compréhension des liens entre la France et d’autres pays dans le monde.
Le numérique éducatif au service de la coopération francophone : une question de contextualisation
Authors: Le Fur Stéphane , Galindo Luis , Vetter Anna
Published: March 2024

La conception de dispositifs, d’outils et de ressources numériques est souvent interrogée par les praticiens impliqués dans les projets de coopération en éducation. Comment favoriser l’appropriation, par les bénéficiaires du projet, de ressources pédagogiques produites par d’autres ? Initié par l’UNESCO, le projet Imaginecole 1 , à l’instar d’autres projets lancés dans une relative urgence lors de la crise du Covid-19, constitue un poste d’observation privilégié pour réactiver la question, sous l’angle de la contextualisation. Cette dimension se révèle d’autant plus nécessaire que le dispositif intègre à la fois des ressources pour enseigner aux élèves et pour l’autoformation des enseignants.
Adapter le temps pour écrire à la performance en frappe au clavier. Une aide aux expérimentations sur les tâches impliquant l’écriture au clavier
Authors: Huret Aurélie , Vié Florian , Brellier Julie , Tricot André
Published: March 2024

Dans la littérature relative aux tâches de dictée, de prise de notes, ou de production écrite, l’habileté graphique et l’habileté dactylographique, qui correspondent à la fluidité d’écriture (précision et vitesse) manuscrite ou tapuscrite, sont généralement prises en compte comme variables indépendantes ou contrôlées. Cependant, aucune étude n’a proposé d’adaptation pour prendre en compte l’hétérogénéité des performances dans le domaine. Dans cet article, nous proposons de répondre à cette limite. Pour cela, notre étude a testé l’adaptation du temps d’écriture dans une tâche de transcription en fonction des performances individuelles en dactylographie. La moitié des participants a bénéficié d’une adaptation du temps d’écriture à leurs performances dactylographiques ; l’autre moitié n’a pas bénéficié de cette adaptation. Les résultats mettent en évidence une réduction significative de la variance inter-individuelle pour le groupe ayant bénéficié de l’adaptation. Ces résultats ajoutent de nouvelles données à l’étude expérimentale sur les tâches de dictée, de prise de notes, et plus généralement de production écrite et contribuent à l’optimisation du protocole expérimental. Cette étude confirme également le lien entre performances dactylographiques et d’autres performances, ici en transcription.
Réduire les inégalités en résolution de problèmes. Travailler la compréhension avant les données numériques
Authors: Claracq Ingrid , Fayol Michel , Vilette Bruno
Published: March 2024

Nous testons l’hypothèse que les performances en résolution de problèmes arithmétiques (RDP) pourraient être améliorées en privilégiant dans un premier temps la compréhension des énoncés verbaux avant d’introduire les données numériques et le calcul. Pour cela, nous comparons selon un protocole pré-test - intervention (12 semaines) – post-tests (immédiat et différés), les performances de deux groupes d’élèves de CE2 (groupes expérimental GE et contrôle GC) scolarisés en milieu REP (réseau d’éducation prioritaire) et en milieu Non REP. Les deux groupes composés de 22 classes et comprenant au total 389 élèves, sont confrontés chaque jour pendant 12 semaines au même ensemble d’énoncés. L’un (GE, N = 199) apprend d’abord à traiter les énoncés sans valeurs numériques avant de disposer des données numériques alors que l’autre (GC, N = 190) procède de manière usuelle. Le travail initial du GE sur la compréhension améliore significativement et durablement les performances et réduit les différences interindividuelles en RDP, notamment en REP, comparativement à une approche classique (GC).
Réflexion sur les enjeux de l’adoption des robots sociaux : avantages, menaces, freins et dérives
Authors: David Dayle , Milhabet Isabelle
Published: March 2024

Dans la mesure où la place des robots sociaux croît rapidement, leur intégration soulève des questions d’actualité à la fois psychologiques, sociales et éthiques. Cet article propose une réflexion sur les enjeux de leur adoption. Conçue pour accompagner et soulager, leur adoption donne lieu à des bénéfices notables dans différents domaines. Leurs avantages demeurent toutefois insuffisants pour compenser les menaces qu’ils représentent et les freins possibles à leur adoption. Les déterminants et les conséquences des avantages, menaces, freins et dérives sont individuels, sociaux, sociétaux. L’objectif de cette réflexion est double : d’une part, s’interroger sur les enjeux à ne pas les utiliser et, d’autre part, mieux comprendre les risques et dérives afférents à leur introduction. Ce double objectif s’inscrit dans une réflexion sur ce qui est accepté et sur ce qui est acceptable en matière de robotique sociale.
Journal d’une rencontre rythmique (Extraits)
Authors: Gateau-Brochard Laurence
Published: March 2024

L’auteure propose de la suivre dans sa quête de rencontrer l’autre, tellement autre que tous les repères disparaissent. Comment trouver appui lorsque l’étrange nous saisit. Alors reste et survient l’élémentaire, émergeant de nulle part, un ailleurs aux sources de la vie. Des mouvements et des sons, aux racines de notre corporéité, le rythme.
Quand tout bouge, qu est-ce qui tient ?
Authors: de Maillard Flore
Published: March 2024

Au cours de séances de gestalt-thérapie itinérantes en plein air, l’autrice s’intéresse au concept de contact organisme/ environnement. Elle interroge le cheminement comme un cadre structurant où les données du terrain foulé et le rythme du vivant soutiennent le processus thérapeutique.
La carrière numérique de Mathilde : imagination, expérience et désillusion à l’ère des rencontres en ligne
Authors: Bietti Federico
Published: March 2024

L’article propose une interprétation théorique du processus de rupture entre les attentes créées par les conversations sur les applications de rencontres et le moment du premier face-à-face. Cet effet est connu par les utilisateurs de ces applications. Néanmoins, il a été moins analysé dans la littérature. Dans un premier temps, l’auteur analyse le processus de désillusion à l’ère de la rencontre en ligne. Ensuite, à travers la phénoménologie sociale et la sociologie interactionniste, l’article présente une interprétation de ce phénomène d’une part par les dynamiques de la rencontre en ligne qui commence dans la sphère des contemporains pour avancer vers la sphère des consociés, selon la théorie socio-phénoménologique et, d’autre part, par la production d’une identité virtuelle qui nécessite confirmation dans la réalité hors ligne, selon la sociologie interactionniste.
Les Aventures du capitaine Hatteras de Jules Verne : le sujet psychotique, héros de l’impossible
Authors: Brémaud Nicolas
Published: March 2024

La littérature offre parfois de saisissants éclairages de la clinique. C’est le cas ici des Aventures du capitaine Hatteras de Jules Verne, où, au-delà de la finesse de la description de l’entrée dans la psychose et du déclenchement du délire du personnage principal, Hatteras, qualifié de « héros de l’impossible » par l’écrivain, se dessine l’articulation des concepts lacaniens d’« impossible » et de « réel ». Un parallèle intéressant pour permettre d’envisager cette dimension héroïque chez les patients, qui, eux aussi, se heurtent chaque jour de façon abrupte au réel, tentent d’y parer, de s’en défendre… quitte à délirer.
Le style de leadership et le comportement intrapreneurial dans les organisations marocaines : essai de modélisation
Authors: Arbaoui Saifeddine , Jemjami Nadia
Published: March 2024

Dans un environnement complexe, les initiatives individuelles des employés peuvent constituer un levier de performance pour les organisations. L’émergence des initiatives individuelles, qualifiées d’actions intrapreneuriales, dépend, dans une large mesure, de la qualité et du style du management. Cet article vise à évaluer l’impact du style de leadership et de l’identification organisationnelle sur le comportement intrapreneurial des collaborateurs. A travers une étude quantitative par régression par les moindres carrés partiels, nous avons modélisé les données collectées auprès de 689 collaborateurs d’organisations marocaines publiques et privées, marchandes et non marchandes. Les résultats confirment le rôle vital du leadership transformationnel dans la promotion des actions intrapreneuriales.
Aux origines de la piraterie, richesse et gloire
Authors: Muffat Sophie
Published: March 2024

La piraterie est une réalité ancienne qui débute durant l’Antiquité avec l’objectif de piller pour s’enrichir. À partir du XVI e siècle, la guerre de course voit l’émergence du corsaire qui, lui, agit pour le compte d’un souverain. Aujourd’hui encore, il existe un mythe du « pirate illustre » notamment au cinéma. Et pourtant la piraterie reste une réalité dans certaines mers, obligeant les États à intervenir.
Amérique latine
Authors: Drouhaud Pascal , Biroste David
Published: March 2024

Le contentieux territorial entre le Venezuela et le Guyana sur la région frontalière de l’Essequibo s’est récemment aggravé. Caracas regarde avec envie les ressources potentielles de cette partie de la forêt amazonienne. Les États-Unis et d’autres partenaires comme le Royaume-Uni se sont investis afin de réduire les tensions et un risque de dérapage.
Widefield, Swept-Source Optical Coherence Tomography Angiography Metrics as Predictors of Anti-VEGF Treatment in Retinal Vein Occlusions
Authors: Finn Matthew J. , Baldwin Grace , Lains Ines , Garg Itika , Wescott Hannah , Vingopoulos Filippos , Zeng Rebecca , Choi Hanna , Tracy Jack , Razavi Peyman , Sayeh Diane , Patel Nimesh A. , Wu David M. , Vavvas Demetrios G. , Miller John B.
Published: March 2024

Background and Objective:

Our objective was to assess baseline widefield swept-source optical coherence tomography angiography (WF SSOCTA) microvascular metrics as predictors for the number of anti-vascular endothelial growth factor (VEGF) injections and visual acuity (VA) at 12-months follow-up in patients with retinal vein occlusion (RVO).

Patients and Methods:

This was a prospective study including 49 RVO eyes from 49 patients who had not received an anti-VEGF injection for at least 3 months prior to imaging. Microvascular metrics from 6×6-mm and 12×12-mm angiograms were assessed using linear regression models, adjusting for age.

Results:

Reductions in the vessel density (VD) and vessel skeletonized density (VSD) vascular metrics were associated both with a higher number of anti-VEGF injections at all follow-up time points and reduced VA 12 months after imaging in all RVO eyes.

Conclusions:

WF SS-OCTA VD and VSD micro-vascular metrics at baseline can prognosticate VA and number of anti-VEGF injections required at 3, 6, and 12 months in RVO eyes.

[
Ophthalmic Surg Lasers Imaging Retina
2024;55:374–382.]
Scleral Fixated Secondary IOLs: An Outcomes Comparison Between the Yamane and Gore-Tex-Sutured Techniques
Authors: Drummond Sean C. , Feist Jack E. , Crosson Jason N. , Haider Asghar A. , Fuerst Jonathan S. , Hughes Devon Askins , Feist Richard M.
Published: March 2024

Background and Objective:

Among secondary intraocular lens (IOL) techniques, scleral fixated IOLs (SFIOLs) offer advantages in cases without capsular support. In this article, we compare outcomes between two types of Gore-Tex scleral sutured IOLs with the Yamane technique.

Patients and Methods:

This study was a retrospective chart review of patients who underwent SFIOL implantation.

Results:

Analysis revealed a statistically significant improvement in final postoperative visual acuity (VA) for sutured SFIOLs (
P
< 0.001, Envista (
n
= 29) 95% CI 0.47 to 1.04, Akreos (
n
= 23) 95% CI 0.32 to 0.81) with no statistical improvement in the Yamane group (
P
= 0.44,
n
= 15, 95% CI −0.33 to 0.71). Outcomes analysis revealed greater incidences of cystoid macular edema (CME) in the Yamane cohort (
P
< 0.05) and a higher rate of reoperations in the Akreos cohort (
P
< 0.02). All complications related to suture material (
n
= 4) and IOL decentration (
n
= 2) occurred in the sutured SFIOL group.

Conclusions:

The sutureless Yamane technique offered fewer subsequent surgeries and suture-specific complications while revealing diminished VA improvement in long-term follow-up compared to the sutured SFIOLs.

[
Ophthalmic Surg Lasers Imaging Retina
2024;55:384–390.]
Case Report: Macula Structural and Functional Assessment in Nab-Paclitaxel–Related Cystoid Macular Edema
Authors: Kwok Lawrence , Mahmood Alina , Kumar Sanjeev , Chang Andrew
Published: March 2024

Nab-paclitaxel–related cystoid macular edema is a rare ophthalmic adverse drug reaction. We present a 54-year-old woman with metastatic hormone receptor positive, HER-2 negative breast carcinoma who developed profound bilateral vision loss after the seventh cycle of nab-paclitaxel treatment. Optical coherence tomography and macula microperimetry demonstrated macular edema and decreased threshold sensitivity, respectively. Cessation of nab-paclitaxel improved structural and functional vision after 4 weeks. The introduction of topical dorzolamide 1% in one eye demonstrated further rapid resolution of edema. We demonstrate the objective and subjective visual changes and recovery of nab-paclitaxel–related cystoid macular edema.

[
Ophthalmic Surg Lasers Imaging Retina
2024;55:408–411.]
Environmental resilience: transition to regenerative supply chain management
Authors: Ali Jamshid
Published: March 2024

Global supply chains face mounting pressures for sustainability, necessitating a shift from Green Supply Chain Management (GSCM) towards regenerative supply chain management (RSCM) to address environmental concerns and enhance Resilience. This transition addresses environmental concerns while improving and supporting Resilience within supply networks. My aims were twofold: (1) To assess the resilience-enhancing mechanisms during the transition to RSCM through a comprehensive review process, and (2) to uncover critical factors and themes of the RSCM. The study employed qualitative interviews as the primary method to collect data using a structured questionnaire. The study adopted snowball sampling based on the referral and recommendation of the respondents. The study investigated vital strategies and challenges for adopting RSCM, explicitly focusing on environmental sustainability. The results indicated that the transition emphasizes a shift from harm reduction to ecosystem restoration, highlighting the importance of environmental restoration in RSCM. Additionally, RSCM places a pronounced emphasis on resilience-building strategies compared to GSCM, underscoring the need for more comprehensive integration of Resilience within supply chains during this transition, particularly in an environmental context. I also developed a framework illustrating the transition from GSCM to RSCM, emphasizing environmental considerations. Additionally, this study contributes novel insights into the dynamic landscape of sustainable supply chain management, emphasizing the importance of resilience-building strategies, particularly in an environmental context, during the shift to RSCM.
An unconditionally stable numerical scheme for competing species undergoing nonlocal dispersion
Authors: Han Jianlong , Armstrong Seth , Duffin Sarah
Published: March 2024

Nonstandard numerical approximation for the study of a competition model for two species that experience nonlocal diffusion, or dispersion, allows for faithful representation of the theoretical solution to the system. Such a scheme may preserve positivity of solutions, be uniquely solvable, and be completely stable. Under appropriate conditions, the error between the scheme and the theoretical solution can be measured. We present such a scheme here and confirm its desirable properties as they reflect the solution to the system.
Piecewise immunosuppressive infection model with viral logistic growth and effector cell-guided therapy
Authors: Zhang Xiong , Xiang Zhongyi
Published: March 2024

This work investigated a piecewise immunosuppressive infection model that assessed the effectiveness of implementing this therapeutic regimen once the effector cell count falls below a specific threshold level by introducing a threshold strategy. The sliding mode dynamics, global dynamics, and boundary equilibrium bifurcations of the Filippov system were examined based on the global dynamics of the two subsystems. Our primary findings indicate that the HIV viral loads and effector cell counts can be stabilized within the required predetermined level. This outcome depends on the threshold level, immune intensity, and the initial values of the system. Therefore, properly combining these key factors makes it possible to effectively curb the abnormal increase of virus and keep the effector cells at a reliable level. This approach maximizes the controllable range of the HIV. The proposed switching system incorporating pseudo-equilibrium exhibits three types of equilibriums that could be bistable or tristable. It means there is a possibility of controlling the virus after administering therapy if the immune intensity $ c $ is limited within the range of the post-treatment control threshold and the elite control threshold when $ {R_0} > {R_{{c_1}}} > {R_{{c_2}}} > 1 $.
Probabilistic properties and estimation methods for periodic threshold autoregressive stochastic volatility
Authors: Ghezal Ahmed , Alzeley Omar
Published: March 2024

In an endeavor to encapsulate the dual aspects of volatility progression and periodicity inherent in autocorrelation frameworks demonstrated by various nonlinear time series, a novel conceptualization emerges—the periodic threshold autoregressive stochastic volatility (PTAR-SV) model. This model served as a viable alternative to the conventional periodic threshold generalized autoregressive conditional heteroskedasticity (TGARCH) process. The inherent probabilistic framework of the PTAR-SV model incorporated certain essential features, including strict periodic stationarity, enhancing its analytical robustness. Additionally, this study established the conditions for higher-order moments to exist within the PTAR-SV model. The autocovariance structure pertaining to the powers of the PTAR-SV process has been studied. The process of parameter estimation was scrutinized via the quasi-maximum likelihood technique. This estimation approach involved assessing likelihood using prediction error decomposition and Kalman filtering. Moreover, we extended our analysis to include a Bayesian Markov chain Monte Carlo (MCMC) method based on Griddy-Gibbs sampling, particularly suitable when the distribution of model innovations follows a standard Gaussian. Through a simulation study, we evaluated the performances of both the quasi-maximum likelihood (QML) and Bayesian Griddy Gibbs estimates, providing valuable insights into their respective strengths and weaknesses. Finally, we applied our newly developed methodology to model the spot rates of the euro against the Algerian dinar, demonstrating its applicability and efficacy in real-world financial modeling scenarios.
DNA methylation differences in genes associated with human personal disorders and deviant behavior
Authors: Mosse I. B. , Sedlyar N. G. , Mosse K. A. , Kilchevsky A. V.
Published: March 2024

Epigenetic regulation of gene expression is involved in the progression of mental disorders, including deviant behavior, brain developmental, and personality disorders. The large number of genes has been studied for their activity association with stress and depression; however, the obtained results for the majority of these genes are contradictory. The aim of our study was to investigate the possible contribution of methylation level changes to the development of personality disorders and deviant behavior. A systematic study of CpG Islands in 21 target regions, including the promoter and intron regions of the 12 genes was performed in DNA samples extracted from peripheral blood cells, to obtain an overview of their methylation status. High-throughput sequencing of converted DNA samples was performed and calling of the methylation sites on the “original top strand” in CpG islands was carried out in the Bismark pipeline. The initial methylation profile of 77 patients and 48 controls samples revealed a significant difference in 7 CpG sites in 6 genes. The most significant hypermethylation was found for the target sites of the HTR2A (p-value = 1.2 × 10−13) and OXTR (p-value = 2.3 × 10−7) genes. These data support the previous reports that alterations in DNA methylation may play an important role in the dysregulation of gene expression associated with personality disorders and deviant behavior, and confirm their potential use as biomarkers to improve thediagnosis, prognosis, and assessment of response to treatment.
Sciences sociales par temps de crise
Authors: Fassin Didier
Published: March 2024

Écologique, sanitaire, énergétique, économique, sociale, humanitaire, démocratique : les crises sont une composante essentielle du monde contemporain. Si les sciences sociales peuvent aider à les comprendre et à les résoudre, leur rôle est également d’interroger le langage de la crise, d’analyser l’écart ou la convergence entre la réalité et sa représentation : nommer ou taire une crise, l’exagérer ou la minimiser sont autant de procédés générateurs d’affects, de temporalités, d’omissions aux conséquences majeures qu’une pensée critique se doit de décrypter.S’appuyant à la fois sur les trajectoires de vie de figures célèbres des sciences humaines et sur des recherches conduites autour de faits éloquents du présent, cette leçon inaugurale, qui s’adresse à toute citoyenne et tout citoyen, pose les jalons d’une vaste réflexion éthique et politique dont l’époque ne cesse de démontrer la nécessité.
The dukes of Normandy in Eton College ms. 96 and the reception of Norman history in thirteenth-century England
Authors: Cleaver Laura
Published: March 2024

Eton College ms. 96 contains a diagram that charts history from the creation of Adam to the middle of the thirteenth century. It was probably made at Glastonbury c. 1250. Among the rulers represented in roundels connected by lines are the dukes of Normandy. Much of the text for the dukes is derived from Robert of Torigni’s chronicle (compiled at Le Bec), demonstrating not only the importance of the dukes of Normandy for the history of the English monarchy, but also providing evidence for the reception of Torigni’s chronicle in the west of England. In addition, the compiler of the Eton manuscript used stories only recorded in the vernacular history written by Wace. But while the latter suggests an interest in some of the colourful stories associated with the dukes, the rubrics identifying the earliest dukes seem to have been mistakenly applied to images in the line of the Byzantine emperors. This draws attention to the challenges of creating or copying such diagrams, but also suggests that two hundred years after the Norman conquest, the Norman ancestors of the English kings were not figures treated with particular care.
Research on the Design of Power Supply Gateway and Wireless Power Transmission Based on Edge Computing
Authors: Wang Zemin , Ping Jianmiao , Fu Junwei , He Yuedeng , Li Changchun
Published: March 2024

There is a rising need for sensors under an IoT network to identify and monitor the environment as more IoT devices and services are made accessible for use. This movement presents challenges such as the proliferation of data and the scarcity of energy. This research presents a strategy for enhancing the service provision capabilities of WSN-aided IoT applications by combining mobile edge computation with wireless signal and control transmission. In order to reduce overall system energy consumption while maintaining data transmission rate and power needs, a new optimization problem integrating power allocation, CPU frequency, offloading weight factor, and energy harvesting is devised. The non-convex nature of the problem necessitates the development of a novel ideal solution group iterative process optimization model that divides the original problem into multiple subproblems, with each subproblem being optimized in turn. According to the results of simulations with a numerical model, our proposed method consumes considerably less energy than just the two benchmark methodologies.
Ten Years of SME E-Commerce Performance Factors and Metrics, 2011-2021
Authors: Salazar-Kovaleff Miguel , Mauricio David
Published: March 2024

Small and medium enterprises (SMEs) generate 90% of employment and contribute more than 50% to the world product, where e-commerce (EC) is fundamental to their development. In this study, a systematic review of literature from indexed journals in Scopus and Web of Science is conducted, 73 primary studies are identified to answer the inquiry: What affects EC performance and how is it measured? Twenty-eight definitions for EC, 70 ways of understanding performance in three perspectives (financial, customer-market, and process), 51 metrics to measure them, and 74 factors that affect these were identified. However, there is a lack of studies on performance factors from its process as well as the metrics that contemplate other perspectives, such as technological innovation, social responsibility, and value co-creation. Additionally, studies on factors are oriented to the result but not to the process that generates said result, which means there is a gap to be studied.
Social, behavioral and environmental determinants of vector-borne diseases: A narrative review of evidence and implications for integrated control approaches
Authors: Alqassim Ahmad Y
Published: March 2024

Vector-borne diseases exert immense health burdens worldwide. Malaria alone causes over 200 million cases and 600,000 deaths annually. Transmission involves complex drivers requiring examination beyond entomological factors. A systematic literature search across databases identified relevant studies on vector-borne disease determinants published in the last two decades, with priority given to rigorous designs like longitudinal analyses, reviews, and meta-analyses from diverse epidemic regions, allowing narrative synthesis of key determinants, relationships, and gaps. This narrative review synthesizes evidence on social, behavioral, and environmental determinants of major vector-borne disease risks over the past decade. Lower education, poverty, unplanned urbanization, gender inequities, inadequate water and waste management, climate variations, and land-use changes stood out as key determinants. However, significant knowledge gaps remain around quantifying precise threshold effects and impacts of tailored interventions across contexts. A social-ecological perspective recognizing interdependencies between determinants should frame integrated control programs. Multicomponent strategies addressing environmental modifications, protective measures, behavioral motivators, and infrastructure alongside governance and community engagement require implementation research and impact evaluation. Overall, this review highlights priority areas for advancing evidence-based vector control through contextualized, determinant-targeted policies and interventions. Further research incorporating modeling, trials, and cost-effectiveness analyses is critical to validate approaches that address influential drivers, leverage motivators, and reduce the global burden.
Cone-beam computed tomographic evaluation of biodentine apexification for traumatized necrotic immature permanent incisors: One-year clinical study
Authors: Pavula S. , Sherwood I. Anand , Amaechi Bennett Tochukwu , Murugadoss Vaanjay , Prakasam Ernest Prince , Abirami A. Azhagu
Published: March 2024

Aim:

The aim of this study was to assess the outcome of biodentine apexification for the management of traumatized immature teeth with necrotic pulp over a period of 12 months.

Methods:

Eighty-five human maxillary incisors with traumatized immature necrotic pulp in patients aged 10–50 years were selected for this study. Root canal treatment was initiated and the biodentine apexification procedure was performed in a single appointment for all teeth. Intraoral preoperative and postoperative periapical radiographs were used to assess periapical (PA) changes, changes in root length (RL), and radiographic root area (RRA). Preoperative and postoperative cone-beam computed tomography (CBCT) images were used to assess the three-dimensional (3D) volumetric changes. Patients were recalled at 12 months posttreatment for the evaluation of clinical symptom, percussion, and palpation examination. Descriptive statistics was computed for preoperative demographic, patient-centric data, and treatment success. Paired t-test was used to compare the preoperative and 12-month postoperative changes in RRA, RL, and 3D volumetric changes of the parameters.

Results:

Forty-eight out of the 49 teeth that completed the study were asymptomatic and functional. Comparing the preoperative and the 12-month review radiographs using the periapical index scores based on the size of the lesion, completely healed lesions were 79.16% while lesions in the process of healing were 20.83%. There was a significant (P < 0.05) increase in RL (14.17%), RRA (40.87%), and dentin volume (26.63%).

Conclusion:

3D volumetric analysis suggests that biodentine apexification has the ability to deposit hard tissue 3-dimensionally, and it is an effective alternative to the conventional apexification materials.
Comparison and analysis of ProTaper, ProTaper Next, and ProTaper Gold using finite element analysis
Authors: Makade Chetana S. , Shenoi Pratima , Khapre Rajendra
Published: March 2024

Aim:

The aim of this study is to compare three endodontic files: ProTaper Universal (PTU), ProTaper Next (PTN), and ProTaper Gold (PTG) under bending forces using finite element analysis.

Methods:

This study utilizes finite element analysis conducted with ANSYS software. 3D models of the three endodontic files were prepared using ANSYS. A non-linear material model was applied, idealizing the stress-strain curve for Nickel-Titanium alloy (NiTi), the material of these endodontic files. Static and transient analyses were performed to identify three different material phases: austenitic phase, transition phase, and martensitic phase.

Results:

Finite element analysis reveals that the PTU file exhibited a maximum von Mises stress magnitude of 1249.7 MPa, PTN showed a maximum von Mises stress magnitude of 798.16 MPa, whereas the PTG file showed a minimum von Mises stress magnitude of 465.68 MPa. PTN showed more bending compared to the other file models for the same load magnitude. PTN remained in the austenitic phase until a tip displacement of 7.3657 mm, while PTU reached a maximum displacement of 4.5633 mm in the austenitic phase.

Conclusion:

The study concludes that the PTU file is the most rigid among the three file models. PTU generates higher stress magnitudes compared to the other files; thus, it is more likely to fracture under lesser bending forces. The study also concludes that PTG exhibits higher displacement with the lowest von-Mises stresses, making it the most flexible file among the three models.
Seizure in the Immediate Postrenal Transplant Period – A Diagnostic and Therapeutic Challenge
Authors: Pawar Sridatta Gurudatta , Selvanathan Deepak Kumar , Thoppalan Balasubramaniyan , Ramadoss Karthika , Anbuselvam Bharathi Sezhain
Published: March 2024

ABSTRACT

Seizures postkidney transplant occur in 11.4% of recipients and major causes include immunosuppressive drugs, metabolic derangements, central nervous system infections, and posterior reversible encephalopathy syndrome (PRES). PRES is described as an acute clinical-radiological phenomenon commonly associated with hypertensive emergencies, preeclampsia, and neurotoxic effects of immunosuppressive medications. Herein, we describe a young male presenting with seizures 14 h after a successful live-related kidney transplant with magnetic resonance imaging (MRI) of the brain (MRI-T2/FLAIR) showing hyperintense bilateral parietal-occipital and parietal-temporal region suggestive of PRES. The patient was managed without switching or reduction of immunosuppression and the patient recovered with resolution of MRI changes 6 weeks posttransplant with blood pressure control.
Coexistence of Type I Diabetes and Lupus Nephritis in a Young Child
Authors: Badge Rohit , Rathore Vinay , Ghosh Amritava , Saha Anish Kumar , Pathak Naman
Published: March 2024

ABSTRACT

Systemic lupus erythematosus (SLE) and type I diabetes (T1D) are autoimmune diseases that rarely occur together in the same patient. Both SLE and T1D are frequent causes of end-stage renal diseases if not treated adequately. The rate of progression of chronic kidney disease will be higher if T1D and SLE coexist in the same patient. We present a case of a 13-year-old female child with T1D and SLE. Only a few case reports of coexisting T1D and SLE are mentioned in the literature. Our case probably is one such rare case in a child with both T1D and SLE.
Human Leukocyte Antigen Typing in Organ Transplantation: Methods, Clinical Relevance, and Practical Applications
Authors: Tapiawala Shruti , Jogale Suchita
Published: March 2024

ABSTRACT

Transplantation of tissues and organs is one of the greatest achievements of this century. Antigens which vary between members of same species are known as allo-antigens. Difference in the allo-antigens between the donor and the recipient represents the antigenic stimulus, which can cause rejections. Adaptive immunity identifies self from non-self. The main objective of the immune response is to identify the cell surface molecules (major histocompatibility complex /MHC) expressed on the donor cells. It is imperative that human leukocyte antigens (HLA) antigens are identified to gauge the mismatches. Presence of pre formed HLA antibodies or formation of de-novo HLA antibodies against these mismatched antigens can lead to antibody mediated rejections and decreased allograft survival. Identification and monitoring of these antibodies pre transplant and post-transplant by performing a virtual cross-match with mismatched donor antigens help in planning and adjusting immunosuppression. A precise and adequate HLA typing of the donor and recipient is required for virtual cross-match. HLA typing technologies have advanced from serological typing to molecular technologies, which can now help identify the donor tissue to allelic level. Methods of HLA typing and their applications with cases have been described in this article.
Evaluating a research methodology workshop among postgraduate students using Kirkpatrick’s model
Authors: Debata Ipsita , Nayak Smrutiranjan , Ahmed Sakir , Behera Basanta Kumar , Padhee Sourav
Published: March 2024

BACKGROUND:

In this era of evidence-based medicine, only systematic research can help in providing judicious and precise healthcare to individual patients based on updated knowledge and skills. However, many medical professionals do not feel competent and confident enough to conduct research. One of the reasons could be the lack of a research-based curriculum in undergraduate courses. The National Medical Council has also stressed the need for formal training in research methodology for healthcare professionals. The research methodology workshops help to familiarize the participants with basic, clinical, and translational research required to impart optimum patient care. The objective of our study was to evaluate a research methodology workshop conducted for postgraduate students by assessing the participant’s knowledge, feedback, and expected impact using Kirkpatrick’s evaluation model.

MATERIALS AND METHODS:

A quasi-experimental, single-group study was conducted among 132 first-year postgraduate students. The four levels of Kirkpatrick’s model were applied for evaluation. Feedback forms, scores of the pretest and posttest, quality of the research proposal drafted by the postgraduates for their thesis, and finally successful submission of the research proposal were the components used to evaluate the four levels of outcome of Kirkpatrick’s model.

STATISTICAL ANALYSIS:

Data collected were compiled and tabulated into MS Excel. Proportions were calculated for categorical variables and mean and standard deviation (SD) for scores. A comparison of means between pre- and postworkshop scores was made with paired t-test. A value of P < 0.05 was considered statistically significant. Statistical analysis was done using IBM SPSS Statistics version 20.0 software.

RESULTS:

Out of 132 participants, 29% (38) were males and 71% (94) were females. The mean ± SD pretest and posttest scores at a 95% confidence interval were 10.55 ± 2.537 and 12.43 ± 2.484, respectively. The difference was found to be statistically significant by paired sample t-test (P < 0.001).

CONCLUSION:

Participant feedback is vital for improving research methodology workshops. The workshop met the overall requirements of the participants. There was a significant improvement in the knowledge of participants after the workshop completion.