bluuebunny/crossref_metadata_2025 huggingface dataset:
Atrial Fibrillation in Cancer Patients who Develop Stroke
Authors: Hamam Ismail , Khamis Alia , Shaban Ala Emad , Altamimi Tamer Salhab , Shkoukani Zakaria Walid
Published: February 2022

Background: Acute ischemic stroke (AIS) and transient ischemic attacks (TIA) are known complications in cancer patients and those with atrial fibrillation (AF). The role AF plays in AIS/TIA in the setting of cancer is unclear.The purpose of this study was to assess the relationship between AF and AIS/TIA in cancer patients.Methods: We conducted a case-control study comparing all patients who developed AIS/TIA from 2014 to 2019 following a cancer diagnosis at King Hussein Cancer Center (KHCC), matched to AIS/TIA-free controls based on age, gender, and cancer site.Results: 272 patients were included (136 per group). The mean age was 63.95 ± 13.06 and 57% were females. The AIS/TIA group had more AF at the time of event (14% vs. 4%, OR: 4.25, 95%-CI: 1.39 - 17.36) and had a larger proportion of death on study conclusion (OR: 9.4, 95%-CI: 3.74 - 23.64). On conditional logistic regression, patients in the AIS/TIA group had higher odds of: AF (OR: 7.93, 95%-CI: 1.6 – 39.18), ischemic stroke before cancer diagnosis (OR: 9.18, 95%-CI: 2.66 – 31.74), being on active cancer treatment (OR: 3.11, 95%-CI: 1.46 – 6.62), dyslipidemia (OR: 3.78, 95%-CI: 1.32 – 10.82), and renal disease (OR: 4.25, 95%-CI: 1.55 – 11.63). On another conditional logistic regression model built to assess the role of the CHA₂DS₂-VASc score, a score of >=2 in males and >=3 in females significantly increased the risk of developing AIS/TIA in cancer patients (OR: 2.45, 95%-CI: 1.08 - 5.58).Conclusion: AF, previous ischemic stroke, active cancer treatment, dyslipidemia, and renal disease are independent risk factors for AIS/TIA and a higher CHA₂DS₂-VASc score significantly increases the risk in cancer patients regardless of AF.
Challenges and Threats to Quality in Scholarly Knowledge Production: Views of Selected Stakeholders from 17 Countries
Authors: Starkey Jesse. C. , Koerber Amy , Cummins R. Glenn , Ardon-Dryer Karin , Eko Lyombe , Kee Kerk F.
Published: February 2022

This study applies Harvey and Green’s (1993) model of quality to scholarly knowledge production. Although studies of quality in higher education have been commonplace for decades, there is a gap in understanding quality in terms of research production from the stakeholder’s perspective. This study begins to fill that gap through a qualitative interview study of quality in the knowledge production process. Stakeholders in all parts of the scholarly knowledge production process, from 17 countries are included in the data sample. Interview data are analyzed through the conceptualizations of quality developed by Harvey and Green (1993), extending the use of the model into the realm of the knowledge production process. Definitions and challenges of quality in producing scholarly knowledge are discussed. The findings indicate a rift between the institutional view of quality and the individual perceptions of quality, suggesting the need for policies aimed at addressing a unification of scholarly knowledge production efforts.
Outbreak of vancomycin-resistant Enterococcus faecium starting among patients admitted to a Surgical Unit in a Swedish county
Authors: Gideskog Maria , Welander Jenny , Hällgren Anita
Published: February 2022

BackgroundVancomycin-resistant Enterococcus faecium (VRE) is a nosocomial pathogen causing infection mainly in patients with critical illnesses in intensive care units, severe underlying disease or weakened immune system. Intensive pre-treatment with antibiotics and use of urinary catheters also constitute a risk. Due to its hardy nature, the bacterium can survive for long periods in a hospital environment. The aim of this study was to describe the investigation of a sudden increase in VRE cases admitted to the Surgical Unit at Vrinnevi Hospital in Norrköping, Sweden, and the control measures taken. MethodsFaeces cultures from patients admitted to the Surgical Unit were obtained, and environmental cultures were collected from different locations in patient rooms and medical devices. In addition, screening samples were obtained from units with high-risk patients in the Östergötland County. Isolates identified as E. faecium were subjected to antibiotic susceptibility testing. Vancomycin-resistant isolates PCR-positive for the vanA/vanB gene were further analysed with whole genome sequencing (WGS). ResultsA total of 35 VRE isolates were found (22 from patients and 13 from the environment). The WGS identified three outbreak clusters, sequence type (ST) 203, ST 1839, ST 80 and one unique clone (ST 612). The ST 203 clone predominated among VRE cases admitted to the Surgical Unit. ConclusionsWith prompt infection control measures, the VRE outbreak was over after approximately four months. To prevent further outbreaks of VRE, active screening, antibiotic stewardship, improved cleaning and hand hygiene, and restriction of multiple-bed rooms are essential.
Bronchial Thermoplasty in severe asthma: a real-world study on efficacy and gene profiling
Authors: Facciolongo Nicola Cosimo , Bonacini Martina , Galeone Carla , Ruggiero Patrizia , Menzella Francesco , Ghidoni Giulia , Piro Roberto , Scelfo Chiara , Catellani Chiara , Zerbini Alessandro , Croci Stefania
Published: February 2022

Background: Bronchial Thermoplasty (BT) is an effective treatment in severe asthma. How to select patients who more likely benefit from BT is an unmet clinical need. Moreover, mechanisms of BT efficacy are still largely unknown. We sought to determine BT efficacy and to identify potential mechanisms of response. Methods: This retrospective cohort study evaluated clinical outcomes in 27 patients with severe asthma: 13 with T2-high and 14 with T2-low endotype. Expression levels of 20 genes were compared by real-time PCR in bronchial biopsies performed at the third BT session versus baseline. Clinical response was measured based on Asthma Control Questionnaire (ACQ) score < 1.5, asthma exacerbations < 2, oral corticosteroids reduction of at least 50% at 12 months post-BT. Patients were classified as responders when they had at least 2 of 3 outcome measures.Results: 81% of patients were defined as responders. BT induced a reduction in alpha smooth muscle actin (ACTA2) and an increase in CD68, fibroblast activation protein-alpha (FAP), alpha-1 and alpha-2 type I collagen (COL1A1, COL1A2) gene expression in the majority of patients. A higher reduction in ubiquitin carboxy-terminal-hydrolase L1 (PGP9.5) mRNA correlated with a better response based on Asthma Quality of Life Questionnaire (AQLQ). Lower changes in CD68 and FAP mRNAs correlated with a better response based on ACQ. Lower levels of occludin (OCLN), CD68, connective tissue growth factor (CTGF), higher levels of secretory leukocyte protease inhibitor (SLPI) and lower changes in CD68 and CTGF mRNAs were observed in patients who had less than 2 exacerbations post-BT. Lower levels of COL1A2 at baseline were observed in patients who had ACQ < 1.5 at 12 months post-BT. Conclusions: BT is effective irrespective of the asthma endotypes and seems associated with airway remodelling. Quantification of OCLN, CD68, CTGF, SLPI, COL1A2 mRNAs could be useful to identify patients with better results. Trial registration: The study protocol was approved by the Local Ethics Committee (Azienda USL-IRCCS of Reggio Emilia - Comitato Etico Area Vasta Nord of Emilia Romagna; protocol number: 2019/0014076) and all the patients provided written informed consent before participating in the study.
Developing and Evaluating an Instrument to Assess Perceptions of an Entry-level Physician Associate Doctoral Degree
Authors: Jun Hyun-Jin , Gordes Karen , Fleming Shani , Kulo Violet , Cawley James , Kayingo Gerald
Published: February 2022

BackgroundMost health professions in the United States have adopted clinical or practice doctorates, sparking an ongoing debate on whether physician assistants/associates (PAs) should transition from a master’s to a doctorate as the terminal degree. Although more studies are expected to be conducted, there is no validated instrument assessing perceptions of various stakeholders regarding an entry-level PA doctoral degree. The objective of this study was to develop and evaluate a novel-self-report measure to assess perceptions of an entry-level PA doctoral degree. MethodsA multifaceted, mixed-methods approach was adopted. Based on a comprehensive literature review regarding the impact of the doctoral transitions in health professions, an initial version of perceptions of an entry-level terminal PA doctoral degree scale (PEDDS) was generated. This scale was pilot tested with a group of PA faculty, students, and clinicians. Then, a cross-sectional survey consisting of 67 items was conducted with a national random sample of 1,368 practicing PAs and PA students. Additionally, semi-structured interviews were conducted to ensure validity of PEDDS. A principal component analysis (PCA) was conducted to reduce the number of items and reveal the underlying structure of PEDDS.ResultsThe PCA confirmed 10 factors of PEDDS consisting of 53 items as the best-fit factor structure with adequate internal consistency of subscales. Those factors include a) expected positive impact on the PA profession, b) expected impact on prerequisites, (c) expected impact on the student preparedness as PA faculty and educators, (d) expected impact on the student preparedness as clinicians, (e) expected impact on accreditation and certification, (f) expected impact on curriculum, (g) expected impact on PA educators, (h) expected positive impact on diversity, (i) expected negative impact on the PA profession, and (j) expected impact on the student competency. ConclusionsThe present study highlights the need to develop valid and reliable measurements to assess perceptions regarding the transition to the entry-level doctorate across health professions. This study could be used to guide further discussion of the entry-level doctorates for PAs and other health professions by bridging the gap of existing literature related to valid, reliable, and standardized measures on this topic.
Evaluation of proximal tubule functions at the children with COVID-19 infections: a prospective analytical study
Authors: Devrim Fatma , Böncüoğlu Elif , Kıymet Elif , Şahinkaya Şahika , Cem Ela , Düzgöl Mine , Kara Aybüke Akaslan , Arıkan Kamile Ötiken , Kantar Aslı , Yılmaz Ebru , Dinçel Nida , Bayram Nuri , devrim ilker
Published: February 2022

Purpose: There are limited numbers of studies focusing on renal effects of COVID-19 infection and proximal tubular dysfunction in children with COVID-19 infections. In this study, we aimed to evaluate the functions of the proximal tubule in hospitalized children with confirmed acute COVID-19. Methods: This prospective descriptive study included the children who were hospitalized for confirmed COVID-19 were included. The diagnosis of proximal tubule injury was based on the presence of at least two of the following four abnormalities including abnormal tubular reabsorption of phosphate, normoglycemic glycosuria, hyperuricosuria, and proteinuria. Results: A total of 115 patients were included in the study. Approximately one-third of the patients had higher serum creatinine levels or proteinuria. Additionally, abnormal renal tubular phosphate loss measured by TMP/eGFR was present in 10 patients (8.7%) and hyperuricosuria was present in 28.6%. Consequently, overall PTD was present in 24 patients (20.8%), and PTD associated with COVID-19 was significantly detected in younger children.Conclusions: Our findings suggested that one in five children with acute COVID-19 infections had proximal tubular dysfunction. The rate of proximal tubular dysfunctions was not so high as in adults but should be kept in mind. The children with COVID-19 infections should be monitored for recovery of proximal tubular functions.
Mechanism Study and the Role of Coupled Surface Plasmon Polaritons in Optical Out-Coupling Enhanced Top-Emitting OLEDs with a Dielectric Capped Ag Cathode
Authors: Wang Xue-Liang , qian min , Zhou Dong-Ying
Published: February 2022

Classical optical transfer matrix method and micro-cavity theory is applied to compute optical out-coupling of Top-Emitting OLEDs (TEOLEDs). Optical paths of various functional organic films and electrode structures are included in the calculations. Fluorescent Alq3 green TEOLEDs were fabricated and tested based on theoretical calculations. For TEOLEDs with Ag cathodes plus NPB coatings, we experimentally observed significant enhancements in optical out-couplings compared to that of with bare Ag cathode. We also found that thin-film optics theory is insufficient to explain the observed enhancement. To explain the experimental results, we incorporated near-field radiation of electric dipole and its interactions with Ag cathode film, i.e., surface plasmon polaritons (SPPs) theory, coupled SPPs in a dielectric/metal/dielectric (D/M/D) structure. Therefore, we demonstrate that optical out-coupling enhancement has three contributing factors in a TEOLED: an increased transmittance of cathode Ag, a varied internal micro-cavity gain, and the dominant improved SPP coupling on both sides of the Ag film cathode.
Associations between perceived participation outside home and types of places visited among persons living with and without dementia: risks perception and socio-demographic aspects.
Authors: Margot-Cattin Isabel , Berchtold André , Gaber Sophie , Kühne Nicolas , Nygard Louise , Malinowsky Camilla
Published: February 2022

Introduction:Participation outside home has recently been given attention with a focus on places visited for persons living with and without dementia. Multiple factors like socio-demographic aspects and risk perception have been shown to influence the perception of participation outside home.Aim and methods:This cross-sectional, explorative study aims to explore how places visited, socio-demographic aspects and risk perception are associated with the perception of participation outside home for a sample of 70 persons living with and without dementia in Switzerland. First, we investigated whether the number of places visited was correlated with the perception of participation outside home; then we added socio-demographic and risk perception factors with a bivariate analysis; and searched for a model using multinomial logistic regressions.Results:The number of places visited was associated with the perception of participation outside home, but only for the group of persons living without dementia (p = .043). Risks of falling (p=.014) and of getting lost (p=.037) were associated for the group of persons living with dementia only. Being able to visit places for recreational and physical activities (p=.005) was associated for the group of persons living without dementia. Discussion and conclusion:The results of the exploration of multiple factors and search for a model, highlights the complexity of participation outside home as a construct. Visiting multiple and various types of places seem to play a role in participation outside home but would need to be further investigated.
Therapeutic potentials of the caffeine in polycystic ovary syndrome in a rat model: via modulation of proinflammatory cytokines and antioxidant activity Running title: The effects of caffeine on rats with polycystic ovary syndrome
Authors: Delbari Ali , Rezaie Mohammad Jafar , Ghoreishi Seyed Amir-Hossein , Golmohammadi Rahim , Nasiry Davood , Rustamzadeh Auob , Raoofi Amir , Ebrahimi Vahid , Khaneghah Amin Mousavi
Published: February 2022

Recent studies have shown that 6-20% of women worldwide suffer from Polycystic ovary syndrome.It is associated with reproductive and metabolic dysfunction.Caffeine is naturally found in tea, cocoa, and coffee.It has shown that caffeine can change hormonal profiles, stimulate ovulation, and enhancing fertility. In this study,the effects of caffeine on PCOS rats were investigated. For this purpose, forty female rats were divided into four groups: the control group(without injection),the PCOS group(injection of 2 mg of estradiol valerate to each rat), the Caffeine group(37.5 mg/kg caffeine),and the PCOS + caffeine group(37.5 mg/kg caffeine).After 21 days of treatment, the ovaries of rats were removed and prepared for further evaluation including H&E staining,TUNEL, Real-time PCR, and biochemical analysis.Administration of caffeine in PCOS mice considerably reduced both the volume of the ovary(p<0.05)and follicular clusters(P<0.01).However, SOD and GPX enzymes were dramatically active in the PCOS + caffeine group compared to the rest(P<0.05). Besides, caffeine treatment in PCOS mice led to Bax reduction and increase of Bcl2 expression. On the other hand, the expression of IL-6 and TNF in caffeine + PCOS were high compared to the other groups.We found that caffeine can reduce apoptosis and inflammation in PCOS ovaries and enhance the unpleasant symptoms of PCOS
Study of Tribological Properties of Human Buccal Epithelium Cells’ Membranes Using Probe Microscopy
Authors: Torhov Nikolay , Mosunov A , Novikov Vadim , Ivonin Ivan
Published: February 2022

In this work the tribological properties of membranes of human buccal epithelium cells of adult in the presence of a protective adsorption buffer layer of ~ 100 nm on their surface were studied using atomic force microscopy in the contact scanning mode. Local mapping of the tribological characteristics of the surface was carried out, viz. friction FL = FL (x, y) and adhesion Fadh=Fadh(x,y) forces were measured.
Analysis of D-Chiro inositol in lowering androgen levels in PCOS patients
Authors: Ashraf Anza , Kundi Muhammad Bilal , Arif Syed Usama , Asif MUhammad , Ilyas Muhammad , Rehan Hafsa
Published: February 2022

Background and objectives: Polycystic ovarian syndrome (PCOS) involves dysfunction in the endocrinal, metabolic and reproductive profile among females. D-chiro inositol is a novel treatment agent for improving the endocrinal profile seen in it. The current study aims to evaluate the effect of D-Chiro Inositol in lowering down the androgens levels in patients with PCOS. Methodology of the study: This randomized trial was carried out at the outpatient of Department of medical sciences during June 2020 to March 2021. 50 females with polycystic ovarian disease were divided randomly into two groups, each of 25 females. One group was give D-Chiro Inositol (600mg/day) and the other was given placebo. Androgens levels i.e. LH, FSH and testosterone were assessed at baseline and then after 8 weeks. Treatment effects were compared after 8 weeks by independent sample T test and a P value of ≤0.05 was considered significant. Results: The mean age of the patients in the treatment (D-Chiro Inositol) group was 28±8 year’s vs 30±9 years in placebo group. The mean BMI of females in D-Chiro Inositol group was 25.7±3.6 kg/m2 compared to 25.8±4.2 kg/m2 in the placebo group. The mean levels of LH, FSH and testosterone were 14.74 mIU/ml, 10.19 mIU/ml and 78.48 ng/dL in D-Chiro Inositol group vs 17.22 mIU/ml, 13.03 mIU/ml and 86.08 g/dl in placebo group. Significant difference was present between both treatment groups (P value ≤0.05). Conclusion: D-Chiro Inositol is a promising drug for the lowering down the androgens levels in polycystic ovarian syndrome.
The importance of the cerebroplacental ratio for the prognosis of neonatal outcome in AGA fetuses
Authors: Mecke Luisa , Ignatov Atanas , Redlich Anke
Published: February 2022

Purpose: As a Doppler sonographic parameter, the cerebroplacental ratio (CPR) provides information about fetal haemodynamics and the redistribution of fetal blood volume in response to a metabolic change. The present study was undertaken to determine the extent to which CPR can be used as a valid parameter in routine obstetric assessment. We investigated whether CPR can be used to assess the neonatal outcome in appropriate for gestational age (AGA) fetuses and its association with secondary caesarean section due to fetal distress. Methods: In this retrospective analysis 1,739 pregnant women were admitted to the University Women's Clinic Magdeburg, Germany, between January 2016 and Dezember 2017. Of them, 800 were eligible for analysis. SGA fetuses with an estimated fetal weight < 10th percentile were excluded from the study. The 710 AGA fetuses were divided in two groups based on the CPR: 669 fetuses showed a normal CPR ≥ 1.08; 41 fetuses showed a decreased CPR < 1.08. Results: In our study cohort decreased CPR in AGA fetuses was associated with threefold increased rate of caesarean sections due to fetal distress (p < 0.001). Our data suggested that low CPR is a reliable predictor of an impaired neonatal outcome in AGA fetuses in terms of a lower birth weight, transfer to neonatology, longer length of hospitalization and the presence of severe morbidity. Conclusion: Decreased CPR in AGA fetuses correlated with impaired neonatal outcome and secondary caesarean section due to fetal distress. The potential role of CPR for obstetric screening should be investigated in further studies.
Text Mining Approaches Oriented on Customer Care Efficiency
Authors: Massaro Alessandro , Magaletti Nicola , Cosoli Gabriele , Giardinelli Vito , Leogrande Angelo
Published: February 2022

In the proposed work is performed a text classification for a chatbot application used by a company working in assistance services of automatic warehouses. industries. Specifically, text mining technique is adopted for the classification of questions and answers. Business Process Modeling Notation (BPMN) models describe the passage from “AS-IS” to “TO BE” in the context of the analyzed industry, by focusing the attention mainly on customer and technical support services where chatbot is adopted. A two-step process model is used to connect technological improvements and relationship marketing in chatbot assistance: the first step provides the hierarchical clustering able to classify questions and answers through Latent Dirichlet Allocation -LDA- algorithm, and the second one executes the Tag Cloud representing the visual representation of more frequent words contained in the experimental dataset. Tag cloud is used to show the critical issues that customers find in the usage of the proposed service. By considering an initial dataset, 24 hierarchical clusters are found representing the preliminary combination of the couple’s question-answer. The proposed approach is suitable to automatically construct a combination of chatbot questions and appropriate answers in intelligent systems.
D-branes and orbit average
Authors: Yang Peihe , Jiang Yunfeng , Komatsu Shota , Wu Jun-Bao
Published: February 2022

We study correlation functions of D-branes and a supergravity mode in AdS, which are dual to structure constants of two sub-determinant operators with large charge and a BPS single-trace operator. Our approach is inspired by the large charge expansion of CFT and resolves puzzles and confusions in the literature on the holographic computation of correlation functions of heavy operators. In particular, we point out two important effects which are often missed in the literature; the first one is an average over classical configurations of the heavy state, which physically amounts to projecting the state to an eigenstate of quantum numbers. The second one is the contribution from wave functions of the heavy state. To demonstrate the power of the method, we first analyze the three-point functions in N=4 super Yang-Mills and reproduce the results in field theory from holography, including the cases for which the previous holographic computation gives incorrect answers. We then apply it to ABJM theory and make solid predictions at strong coupling. Finally we comment on possible applications to states dual to black holes and fuzzballs.
Risk Factors for In-Hospital Mortality among Cancer Patients with
COVID-19: A Cross-Sectional Study
Authors: Abolghasemi Sara , Ghasemzadeh Iman , Mardani Masoud , Mirtalaee Nasrinsadat , Sanadgol Ghazal
Published: February 2022

Background:

COVID-19 has been a major concern for people and healthcare systems
since its emergence in China in December 2019. Patients with medical diseases are at a higher risk
of severe disease development and mortality. Cancer patients are more vulnerable to infections.
Several studies demonstrated that COVID-19 is associated with a greater risk of morbidity and mortality
among cancer patients. However, the risk factors for mortality among these patients are still
unknown.

Objective:

This study aimed to identify the risk factors associated with in-hospital death among cancer
patients with COVID-19.

Method:

In this cross-sectional study, we analyzed demographic data, clinical characteristics and
laboratory parameters of cancer patients with COVID-19 who were hospitalized in three tertiary referral
hospitals in Tehran, Iran from February to May 2020. Diagnosis of COVID-19 was confirmed
using real-time polymerase chain reaction testing and computed tomography scan findings.
Data analysis was performed using SPSS software, version 20. P-value less than 0.05 was considered
significant.

Results:

Sixty-six cancer patients with COVID-19 were enrolled in this study. Among participants,
35 (53.03%) patients were discharged, and 31 (46.97%) patients died in the hospital. Thirty-two
(48.4%) patients suffered from hematologic and 34 (51.6%) from non-hematologic cancers. The
most common comorbidities were hypertension (68.18%) and diabetes (56.06%). The most common
symptoms among patients were rhinorrhea (59.1%), fever (54.5%), and dyspnea (48.4%), respectively.
Diabetes (p= 0.00), hypoxemia (p= 0.005), and receiving chemotherapy or radiotherapy
during the last three months (p= 0.022) were associated with a significantly greater risk of in-hospital
mortality.

Conclusion:

Hypoxemia, diabetes, and the time interval between chemotherapy/radiotherapy and
hospitalization are associated with a higher risk of in-hospital mortality among cancer patients with
COVID-19. These risk factors should be considered in the clinical management of hospitalized
COVID19 patients who suffer from cancers. In-hospital mortality and poor outcomes can be minimized
by addressing risk factors.
Perspectives on Dental Caries: A Cross-Sectional Study among Parents of Primary School Children in Saudi Arabia
Authors: Hashem Danya , Abu Hammad Osama , Farran Jana , Faran Anmar , Odeh Najla Dar
Published: February 2022

Background:

Dental caries is one of the most prevalent chronic childhood diseases affecting many people worldwide. Many people do not recognize the early signs of dental caries or its causes, which is crucial for the prevention and early intervention of the disease and consequently less-invasive and cheaper treatment options.

Objective:

This study aimed to evaluate the perspectives of parents about the meaning, causes, and early signs of dental caries, the association of tooth discoloration with decay, and the effect of different socio-demographic variables on the knowledge of patients regarding caries.

Methods:

Questionnaires were distributed to parents of primary school children in the region of Madinah, Saudi Arabia. Meaning of dental caries, early signs, causes of tooth discoloration related to decay, and the effect of different socio-demographic variables were calculated. Multiple linear regression analysis was carried out to identify significant predictor variables associated with caries knowledge scores.

Results:

There was a total of 2690 respondents. The majority had average caries knowledge scores. Lighter shades of tooth discoloration were reported to be associated with stains and warranted home care only, while darker shades were associated with caries and yielded a necessity for a visit to the dentist. Different socio-demographic variables had an effect on the caries knowledge of the parents.

Conclusion:

There is a need for increased knowledge about the early signs of dental caries among parents. Delayed recognition of signs of dental caries has a detrimental effect on the teeth of children and leads to seeking dental care at the later stages of the disease process. Community-oriented programs are fundamental for improving caries knowledge, its clinical presentations starting from its early signs, causes, and prevention.
The Travelling of News in 1848: The February Revolution, European News Flows, and the Finnish Press
Authors: Hakkarainen Heidi , Rantala Heli
Published: February 2022

This article explores media coverage of the European revolutionary turbulence of 1848, particularly the outbreak of the February Revolution in France. By utilizing several European newspaper repositories, the article sheds light on the role of newspapers in the spread of revolutionary news in the European media space across various political borders and language barriers. In our case study, we examine how information on the February Revolution travelled to the Grand Duchy of Finland, an area situated at the crossroads of different communication networks, that was influenced by the reactionary politics of Russia but still culturally connected with Sweden. Benefitting from digitized collections of Finnish, Swedish, Austrian, German, and British newspapers, this article provides a transnational perspective on the mid-nineteenth-century European media landscape. Instead of trying to encompass a comprehensive outlook on news reporting during the European upheaval in 1848, we are focusing on the emergence of early reports of the outbreak of the February Revolution in various countries, and looking at how the circulation of news was extending or going beyond national boundaries, as news about the revolution arrived in Northern Europe and at the borders of the Russian Empire.
Title: The Quality and Content of YouTube Videos About Herpes Simplex Virus (HSV) in Pregnancy: a Retrospective Review (Preprint)
Authors: Price Meghan J , Birch Eleanor M , Grace Matthew R , Yee Lynn M. , Gray Beverly , Dotters-Katz Sarah K.
Published: February 2022

BACKGROUND

Pregnant individuals often seek online information regarding health concerns on free and accessible platforms such as YouTube. Use of supplemental information may increase when pregnancy is complicated by diagnoses of sexually transmitted infections (STIs) such as herpes simplex virus (HSV) given the sensitive nature of these diagnoses.

OBJECTIVE

The objective of this study is to evaluate the quality and content of YouTube videos about HSV during pregnancy.

METHODS

A search of videos on YouTube was conducted using four ‘HSV and pregnancy’ terms. The first 60 videos from each keyword search were collected and reviewed. The quality and reliability of each video were assessed using the DISCERN instrument and the JAMA Benchmark tool. An expert-developed topic list was used to generate a content score, which assessed video comprehensiveness. Videos were further categorized as either “high” or “low” quality, with high quality videos having both a DISCERN score >3 and a content score >4. Descriptive statistical analyses and comparisons of videos by source, viewing rates, duration, and subscriber number were performed.

RESULTS

A total of 92 unique videos were evaluated; the median content score was 3 out of 7 (IQR 1,5) and median DISCERN score was 2.12 of 8 (IQR 1.75, 2.75), representing moderate video comprehensiveness and low reliability. Only 13 (14.1%) videos met criteria for high quality. Every video categorized as high quality came from medical or online education sources. Low-quality videos had 3.5-times more subscribers & 7-fold higher viewing rates than high-quality videos (p=0.002, p=0.001). Video duration was longer for high-quality videos (15min vs 7.7min; p<0.001).

CONCLUSIONS

Few high-quality, reliable and comprehensive videos regarding HSV in pregnancy exist on YouTube. Low-quality videos generally have more subscribers and views, suggesting that individuals seeking information on YouTube may encounter incomplete resources. This study provides an opportunity for providers to better understand the qualities of online content that is viewed by patients.
El CELA Superior dentro del Sistema de Certificación del CEPE
Authors: Campos Gómez Eva , Cárdenas Sosa Claudia
Published: February 2022

El Certificado de Español como Lengua Adicional (CELA), nivel superior, complementa la serie de tres exámenes (inicial, intermedio y superior) destinados a validar el conocimiento y las destrezas que hablantes de otras lenguas poseen sobre el español.

Dada la importancia que la certificación del español ha ido adquiriendo en el ámbito de la enseñanza de lenguas a nivel internacional, en este artículo se ofrece un panorama general sobre el Sistema de Certificación con que actualmente cuenta el Centro de Enseñanza para Extranjeros (CEPE), para terminar describiendo el CELA Superior (versión 2) último componente de dicho sistema.
Negociando con el canon
Authors: Muñoz Figueroa Jorge Antonio
Published: February 2022

El presente trabajo busca reflexionar sobre la enseñanza de la literatura mexicana a extranjeros que aprenden español como segunda lengua (E/LE) mediante el enfoque intercultural; para tal fin, presento algunas consideraciones que nos llevan tanto a replantear como a reafirmar varios de nuestros criterios sobre tres aspectos: 1) la necesaria negociación que debemos realizar con el canon literario para 2) la elaboración de materiales didácticos y 3) la enseñanza de la literatura a extranjeros en el marco del diálogo intercultural.

La propuesta para llevar a cabo tal negociación es que el docente puede utilizar el canon literario como guía para la sistematización del estudio de la literatura y para la elaboración de antologías de textos literarios para alumnos extranjeros, aunque debe prescindir, en cierta medida, de tal pauta para favorecer una selección más adecuada y más dinámica, de acuerdo al nivel de conocimientos del alumno y a las necesidades tanto del curso como de cada grupo, de ahí la trascendencia de la interculturalidad.
México en la esfera imperial británica, 1763-1848.
Authors: Alatriste Guzmán Oscar
Published: February 2022

El presente artículo tiene como objetivo presentar una interpretación de los intereses imperialistas ingleses en México entre los años de 1763 a 1848, describiendo y explicando algunas de sus principales formas o expresiones, así como épocas o momentos, en que éstos tuvieron lugar aplicando la teoría del llamado imperialismo informal inglés de libre cambio.

Partiendo de la premisa de que este imperialismo convenía más a  los intereses de la Corona inglesa controlar el comercio exterior de  las colonias españolas y posteriormente el de las nacientes repúblicas independientes a poseer colonias formales en la región.
Exámenes de aprovechamiento computarizados
Authors: Campos Gómez Eva , Espinosa Aída , Jurado Salinas Martha
Published: February 2022

En el primer curso de 2011 se implementó en el Centro de Enseñanza para Extranjeros (CEPE) la modalidad computarizada de una batería de siete exámenes (EC), que se administran al final de cada curso intensivo. Éstos se diseñaron con base en el perfil de egreso definido en siete de los ocho programas que conforman el programa de estudios del CEPE, el cual, a su vez, sigue los lineamientos propuestos en el Marco Común Europeo de Referencia para el Aprendizaje, la Enseñanza y la Evaluación de Lenguas (MCER), aparecido en su versión española en 2002. Esta innovación representa una etapa más en el proceso de actualización y estandarización de los cursos de español, que tuvo como punto de partida el año 2000, cuando se empezó a trabajar en un nuevo programa de estudios, el cual entró en vigor en 2007.

El objetivo de este artículo es describir el proceso de elaboración de los EC, el marco teórico-metodológico que los sustenta, así como los resultados preliminares (índices de dificultad de los reactivos) obtenidos en tres aplicaciones llevadas a cabo con 650 estudiantes en total.
La certificación del dominio del español como lengua extranjera en la UNAM
Authors: Samperio Sánchez Luis Miguel
Published: February 2022

La UNAM, a través Centro de Enseñanza para Extranjeros (CEPE), ha realizado la certificación del dominio del español como lengua extranjera desde los años sesenta del siglo pasado; no obstante, es hasta 1997 cuando se aplica el primer examen estandarizado de aplicación masiva. En este artículo se describen y comparan los tres exámenes que el CEPE ha desarrollado para certificar el español como lengua extranjera: Examen de Posesión de la Lengua Española (EPLE), Certificado de Español como Lengua Adicional (CELA), Examen de Español como Lengua Extranjera para el Ámbito Académico (EXELEAA); así como el examen para el Servicio Internacional de Evaluación de la Lengua Española (SIELE), construido entre 2015 y 2016, con el Instituto Cervantes, la Universidad de Salamanca y la Universidad de Buenos Aires.
Acercamientos a la representación de la infancia y la homosexualidad en Los mástiles de Jorge López Páez1
Authors: Muñoz Figueroa Jorge
Published: February 2022

Este artículo analiza dos aspectos específicos –infancia y homosexualidad– en el libro Los mástiles (1955), la primera colección de cuentos escritos por Jorge López Páez (Veracruz, 1922). Eventualmente, ambos temas se hicieron recurrentes en su obra y han adquirido especial atención en la literatura mexicana a partir de la segunda mitad del siglo XX. Varios críticos literarios han delineado el corpus de obras que presentan estos dos temas, ya que ambos incrementaron su importancia y presencia en la literatura de manera paulatina.

Sin embargo, aquellos que se han dedicado al estudio de estos temas han señalado reiteradamente que es necesario lograr una mejor y más amplia investigación con el objetivo de incluir obras literarias y autores que han sido escasamente considerados, que es precisamente el caso de Jorge López Páez. En este artículo se destacan los recursos literarios que fueron empleados en esta colección de cuentos, y pretende mostrar a este autor veracruzano como un referente obligado en lo que respecta a estos dos temas en la literatura mexicana contemporánea.
REPRESENTASI SEMIOTIKA ROLAND BARTHES DALAM SYAIR “AHINNU ILA KHUBZI UMMI” KARYA MAHMOUD DARWISH
Authors: Maulana Ihsan Ahmad
Published: February 2022

Penelitian dilakukan untuk mendeskripsikan pemaknaan denotasi, konotasi dan mitos dalam Syair Ahinnu Ila Khubzi Ummi karya Mahmoud Darwish dengan pendekatan semiotika Roland Barthes. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif dengan landasan dokumen utama yaitu syair Ahinnu Ila Khubzi Ummi. Data penelitian ini adalah data kualitatif berupa fakta, informasi, bait dan gambaran yang diperoleh peneliti dari sumber penelitian, yaitu syair Ahinnu Ila Khubzi Ummi karya Mahmoud Darwish. Adapun teknik pengumpulan data menggunakan pendekatan metode kulitatif deskriptif untuk mengungkap makna denotasi, konotasi dan mitos pada syair. Sedangkan hasil yang diperoleh bahwa penelitian ini menunjukkan adanya diksi-diksi semitotik yang terkandung dalam syair dan dapat diungkap dalam makna denotasi, konotasi, dan mitos. Secara makna denotasi, penyair ingin menyampaikan perasaan rindu yang kuat dan cinta yang mendalam terhadap ibu yang telah memberikannya kehidupan. Sehingga apapun akan dilakukannya untuk melindungi dan membahagiakan ibunya. Adapun makna konotasi, penyair merasakan penyesalan yang hebat dalam dirinya karena tidak bisa berjuang dalam mewujudkan harapan tanah airnya. Mitologi yang terkandung dalam syair, penyair ingin menyampaikan bahwa ketika seseorang jauh dari sesuatu yang biasanya ada didekatnya maka keinginan untuk kembali, melindungi dan berjuang untuk kebaikannya akan menjadi lebih besar daripada selalu berada di dekatnya.
Building a network of points routing for pedestrian panoramic urban areas survey
Authors: Penshin I.N.
Published: February 2022

The author describes technical and algorithmic solution of the task of building a spatial routing network for pedestrian panoramic survey points at monitoring urban infrastructure objects. Its urgency is caused by the necessity of making a panoramic measuring the yard, intra-block territories, as well as park areas and other objects which have no reliable data on the road network there. The matter of spatial routing network providing between panoramic images without reference to the road graph is considered and formulated. Based on the presented conditional variant of solving the task, as well as considering the problem in the view of graph theory, geometric conditions are compiled, the necessary sets of Geodata are determined, and the method of spatial routing network building is developed. Algorithm complexity analysis is performed. An intelligent GIS agent was developed providing filling of the DBMS table with spatial features, which are the object implementation of the spatial routing network in the GIS. Geoportal that helps the final user analyze and adjust the mentioned network with the introduction of changes to the DBMS on the server side in an interactive mode is presented.
Astrometry and Geodesy as a one science. History and assignment of stellar catalogues
Authors: Tolchelnikova S.A.
Published: February 2022

According to the resolution of the International Astronomical Union, since 1999 the main reference for spherical coordinates has become the international celestial reference frame ICRF, compiled from observations of quasars and point-like radio galaxies. This decision abolishes the observations necessary for compiling the traditional spherical coordinate system represented by the fundamental catalogs of the FK series. It is useful to recall the principles of astronomers of the 18th–20th centuries who had organized the determination of the absolute coordinates of stars at the state observatories, required for compiling the next fundamental catalog. This will allow natural scientists who study movements by measured coordinates of celestial objects, firstly astronomers and geodesists, to compare the opportunities provided by optical fundamental catalogs and the reference system of radio coordinates for solving the problems of their branch of science. Let us turn to historical experience, which shows that the establishment of main optical coordinate systems was not a volitional decision but was affirmed in the process of searching for the most effective method for solving both fundamental problems and satisfying current needs of each historical era.
Dialética das nuvens: comentário sobre o texto “Arquitetura da resistência no capitalismo global” de Ricardo Fabbrini
Authors: Pinheiro Machado Francisco De Ambrosis
Published: February 2022

Neste comentário a respeito do texto “Arquitetura da resistência no capitalismo global” de Ricardo Fabbrini, apresentado em evento do GT-Estética da Anpof, em 11 de março de 2021, argumento que uma dialética das nuvens como fundamento de uma estética arquitetônica e artística de resistência ao capitalismo global só pode ser levada adiante quando explicita qual é o momento da negação determinada da mesma.
Star Wars: O despertar do mito
Authors: Vieira Vladimir
Published: February 2022

O artigo tem por objetivo discutir a mitologia em torno da série Star Wars. Inicialmente, argumento que a fascinação provocada pela primeira trilogia decorre de sua capacidade de capturar a época em que foi produzido - a segunda metade dos anos de 1970 - estabelecendo uma relação dialética entre natureza e progresso que tem na tecnologia um de seus pontos nevrálgicos. Em seguida, procuro mostrar que a tentativa de adaptar o mito que se criara a partir do culto à trilogia original com vistas a produzir esse efeito no final do século XX não logrou obter o mesmo sucesso. Por fim, sugiro que a última trilogia - ao menos o primeiro filme, O despertar da força - estabelece uma relação diferente com o seu próprio legado, distanciando-se dele por um duplo caminho: através da melancolia e da crítica.
Mercado Integrado Latinoamericano: diez años después de su creación. Un análisis bibliométrico para el periodo 2008-2021
Authors: Cardona-Montoya Juan Camilo
Published: February 2022

El propósito de este artículo fue analizar las características de la producción investigativa y las temáticas abordadas entorno al Mercado Integrado Latinoamericano -MILA. Utilizando un análisis bibliométrico, a partir de 73 manuscritos publicados entre 2008 y 2021 en revistas indexadas en Scopus, Web Of Science y en otras bases de datos. Los resultados evidenciaron que, la/el docente Daniela Pérez Noreña/Luis Berggrun, la Universidad de Antioquia y Colombia se destacan como el autor, la organización y el país con los mayores niveles de publicación/de conexión. Asimismo, las temáticas de integración financiera e hipótesis de mercados eficientes sobresalen como las de mayor desarrollo científico alrededor de este acuerdo. Pese a lo anterior,  y considerando, además, que la investigación sobre el Mercado Integrado Latinoamericano se está generando de manera fragmentada, con baja conexión entre autores, comunidades de trabajo y literatura previa sobre esta materia, este artículo contribuirá para que, a futuro, nuevas investigaciones puedan proseguir y profundizar de manera empírica en las líneas ya mencionadas y que hasta ahora son consideradas incipientes en el campo investigativo, pero de gran peso en la operatividad del mercado, o en aquellas que, por el contrario, reflejan un moderado avance, aunque con un pronunciado aislamiento entre sus publicaciones.
TOWS Analysis on Recissbar to Increase Its Competitiveness
Authors: Fitriani Efi
Published: February 2022

This study aims to analyze Recissbar's internal and external factors in order to define strategies to increase its competitiveness. Recissbar is a small business in Bandung (Indonesia) that sells traditional Indonesian foods that are very popular in the community. After collecting primary data (from an in-depth interview with the owner of the company), an External Factor Analysis Summary (EFAS) and an Internal Factor Analysis Summary (IFAS) were conducted. Once the company's strengths, weaknesses, opportunities, and threats were identified and a scoring system was established to separate the points that required attention, an analysis using a TOWS graph was performed to determine the most appropriate strategy to implement in the company. This study is descriptive in scope. According to the results and the scores assigned to the external and internal factors, an aggressive growth strategy was found to be the most appropriate. Moreover, the total score of the opportunity and threat factors was 2.5, which suggests that Recissbar responds to existing opportunities by avoiding threats in the same market and has the opportunity to continue to innovate. For its part, the total score of the strength and weakness factors was 2.6, which indicates that Recissbar has the strength of having a good reputation and delicious taste. In general, Recissbar could implement a growth-oriented strategy, particularly by promoting products on social media, cooperating with several mini markets, and doing business-to-business online sales.