bluuebunny/crossref_metadata_2025 huggingface dataset:
Benefícios do uso do óleo essencial de Sálvia esclaréia em ginecologia e no ciclo gravídico puerperal: revisão integrativa
Authors: Janzen Danielle Castro , Menezes Taís Veras de
Published: December 2023

Objetivo: Pesquisar na literatura se o uso do Óleo Essencial de Sálvia Esclaréia pode trazer benefícios à saúde no que tange à ginecologia e ao ciclo gravídico puerperal. Método: Revisão integrativa com busca nas bases de dados: Medical Literature Analysis and Retrieval System on Line, Literatura Latino-Americana de Ciências da Saúde, Cumulative Index to Nursing and Allied Health Literature, Scopus, Embase, Cochrane Library e Web of Science. Como critérios de inclusão foram adotados a correlação com o tema e a disponibilidade na íntegra dos artigos em português, inglês ou espanhol. Os critérios de exclusão foram: duplicidade, artigos de revisão e literatura cinzenta. Resultados: Foram encontrados 229 artigos ao todo, dos quais 16 foram analisados após correspondência com os critérios propostos, sendo divididos em 4 categorias: Atividade antimicrobiana; Efeitos na saúde mental; Efeitos analgésicos e Efeitos antidiabéticos. Conclusão: O uso do óleo essencial de Sálvia Esclaréia pode ser benéfico para a saúde ginecológica e do ciclo gravídico puerperal, sendo necessários mais estudos científicos, principalmente ensaios clínicos randomizados, para que haja mais respaldo e segurança na utilização deste óleo essencial em tratamentos.
Ações de enfermagem para prevenção do câncer de colo de útero na atenção primária à saúde: revisão integrativa
Authors: Reis Bárbara Mayara Costa Barbosa , Pinheiro e Pinheiro Ramon , Pacheco Larissa Kellen Silva , Santos Kezia Cristina Batista dos
Published: December 2023

Objetivo: Buscar na literatura as evidências científicas disponíveis sobre as ações realizadas por enfermeiros na Atenção Primária à Saúde (APS) para prevenção do câncer de colo uterino. Métodos: Trata-se de uma revisão integrativa, norteada pela pergunta: quais as ações realizadas por enfermeiros na APS para prevenção do câncer de colo de útero? Incluíram-se estudos primários, publicados em português e inglês nas bases de dados BDENF, Lilacs e Scielo, entre 2017 e 2021, disponíveis na íntegra. Resultados: A amostra foi composta por 8 estudos. Evidenciaram-se três categorias temáticas: novas ações de enfermagem com foco na educação em saúde, incentivo à vacinação contra HPV e rastreamento por exame citopatológico de colo uterino. Conclusão: Os resultados apontam que há uma concentração de estudos voltados às ações sabidamente conhecidas na prevenção e controle da doença, principalmente, com foco na educação em saúde tradicional, imunização e coleta do exame citopatológico. Entretanto, as evidências indicam novas estratégias que podem ser incorporadas à prática clínica nos serviços de saúde ou associadas às já existentes, visando a melhora no acesso à informação, aumento da procura aos serviços de saúde, detecção passiva, busca ativa e diagnóstico precoce da doença.
A espiritualidade e morte para a enfermagem: uma revisão de literatura
Authors: França Luiz Carlos Moraes , Verdan Dib Rachel , Do Carmo Correia Vanessa , Gomes Rafaela da Conceição , Anjos Marcelly Silva dos , Azevedo Rayza Martins de , Gomes Juliana Rodrigues da Silva , Bezerra da Costa Marcelle Bezerra da , Souza Elizandra Pires Azevedo de , Gaspar Maria Alice Pereira
Published: December 2023

A espiritualidade é compreendida pela busca de sentido da existência, podendo ser utilizada como ferramenta no enfrentamento da morte. Objetivo: Refletir sobre os significados e sentidos da morte e espiritualidade no contexto da equipe de enfermagem. Métodos: Revisão bibliográfica de literatura através do Portal Regional da Biblioteca Virtual em Saúde (BVS), com coleta de dados realizada entre maio e junho de 2023, com o uso dos descritores “Espiritualidade”, “Morte” e “Enfermagem”, conectados pelo operador booleano "AND". Bases de dados: Literatura Latino-americana e do Caribe em Ciências e Saúde (Lilacs), National Library of Medicine (Medline) e Bases de Dados de Enfermagem (BDENF). Critérios de inclusão: artigos publicados em português, com textos completos disponíveis online, entre os anos 2018-2023. Resultados: Após a coleta de dados, a pesquisa identificou uma amostra de 13 artigos. A morte ainda se apresenta como um acontecimento acompanhado de tristeza e sofrimento, sendo a espiritualidade uma alternativa eficaz a fim de amenizar sentimentos negativos. A espiritualidade, quando exercida por um profissional de enfermagem, contribui para uma assistência de melhor qualidade, além da melhor compreensão sobre a morte. Conclusão: A espiritualidade colabora para um melhor enfrentamento do processo de finitude, auxiliando os profissionais de enfermagem que vivenciam a morte.
Correlação entre obesidade central e resistência insulínica em crianças e adolescentes com diabetes tipo 1
Authors: Dias João Pedro Ferreira , Melo Lilia Maria Freires Rodrigues Soares de , Siqueira Rodrigo de Azeredo , Orsini Marco
Published: December 2023

Introdução: Observa-se que o Brasil é o 5º país em incidência de Diabetes no mundo, com 1,1 milhão de crianças e adolescentes portadoras de DM1. Estudos recentes indicam que a resistência insulínica pode estar presente na doença. Como objetivo principal, este trabalho busca avaliar a influência da obesidade central na resistência insulínica em crianças e adolescentes com DM1. Métodos: Estudo de coorte transversal composto por 19 indivíduos, com idade entre 6 e 18 anos diagnosticados com DM1, avaliados de janeiro a dezembro de 2022. Dados: IC; VAI; BSl; BRI;  WHR; WtHR; foram coletados por anamnese e medidas antropométricas, e relacionados utilizando o coeficiente de Pearson com os resultados da equação “eGDR” e “CACTI”.  Resultados: Observou-se que a correlação entre EDC x IFC não demonstrou resultados satisfatórios (p > 0.05), assim como CACTI x VAI (p > 0.05). Entretanto, a correlação entre EDC x CI se mostrou satisfatória (p < 0.001), similar ao observado em EDC x WtHR (p= 0.017), EDC x WHR (p= 0.002), e em EDC x BRI (p < 0.05). Conclusão: Concluímos que quanto maior a gordura corporal central, maior resistência insulínica e maior o índice de volume abdominal, pior a sensibilidade a insulina.
Past, present and future therapeutic approaches in nodal peripheral T-cell lymphomas
Authors: Ngu Henry S. , Savage Kerry J.
Published: December 2023

Peripheral T-cell lymphomas (PTCL) encompass over 30 different entities and although they share post-thymic T- or NK-cell derivation, the disease biology and genomic landscape are very diverse across subtypes. In Western populations, nodal PTCL are the most frequently encountered entities in clinical practice and although important achievements have been made in deciphering the underlying biology and in therapeutic advances, there are still large gaps in disease understanding and clinical scenarios in which controversy over best practice continues. CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone)- based chemotherapy continues to be the ‘standard’ treatment, with the addition of brentuximab vedotin (BV) in the combination CHP (cyclosphosphamide, doxorubicin, prednisone)-BV representing a new treatment paradigm in CD30+ PTCL although its benefit is less certain in the non-anaplastic large cell lymphoma subtypes. Given the high risk of relapse, consolidative autologous stem cell transplant is considered in nodal PTCL, outside of ALK-positive anaplastic large cell lymphoma; however, in the absence of a randomized controlled trials, practices vary. Beyond CHP-BV, most study activity has focused on adding a novel agent to CHOP (i.e., CHOP + drug X). However, with high complete remission rates observed with some novel therapy combinations, these regimens are being tested in the front-line setting, with a particular rationale in follicular helper T-cell lymphomas which have a clear sensitivity to epigenetic modifying therapies. This is well exemplified in the relapsed/refractory setting in which rational combination therapies are being developed for specific subtypes or guided by underlying biology. Taken together, we have finally moved into an era of a more personalized approach to the management of nodal PTCL.
Sản xuất lúa giảm phát thải khí nhà kính tại huyện Thái Thụy, tỉnh Thái Bình: thực trạng và giải pháp thúc đẩy sự tham gia của nông dân
Authors: Nguyễn Thị Hải Ninh , Đỗ Thị Diệp , Nguyễn Hữu Giáp , Lê Thị Tố Uyên
Published: December 2023

Mục tiêu của nghiên cứu là đánh giá thực trạng tham gia sản xuất lúa giảm phát thải khí nhà kính của nông dân huyện Thái Thụy, tỉnh Thái Bình, một địa phương điển hình trong sản xuất lúa tại đồng bằng sông Hồng. Dựa trên dữ liệu thu thập được từ 100 nông dân trồng lúa giảm phát thải khí nhà kính và 50 nông dân canh tác lúa truyền thống, nghiên cứu chỉ ra rằng khi nông dân tham gia trồng lúa giảm khí thải, họ nhận được các hỗ trợ đầu vào và bao tiêu đầu ra từ doanh nghiệp và hợp tác xã. Nhờ sự hỗ trợ này, nông dân thực hành kỹ thuật trồng lúa giảm khí thải tương đối sát với yêu cầu và năng suất, hiệu quả sản xuất lúa cao hơn canh tác truyền thống. Mô hình logit cho thấy các yếu tố ảnh hưởng đến sự tham gia của nông dân trong trồng lúa giảm khí thải bao gồm: giới tính, đặc điểm ưa thích đổi mới của nông dân, tập huấn khuyến nông thường xuyên và tầm quan trọng của cây lúa đối với thu nhập của nông hộ.
Seni pemanfaatan limbah plastik melalui ecobrick sebagai upaya pengelolaan sampah berkelanjutan di sekolah
Authors: Utomo Muhammad Andry Prio , Witjoro Agung , Rakhmawati Yunita , Lelitawati Mardiana , Lestari Sri Rahayu , Maslikah Siti Imroatul , Daniarsih Ajeng , Pratiwi Zahra Anggita , Nirbaya Arindra , Rudianto Rony
Published: December 2023

Sampah plastik masih menjadi pokok permasalahan dalam krisis lingkungan. Plastik juga menjadi penyumbang terbesar dalam kategori sampah anorganik. Pencemaran lingkungan oleh sampah plastik tidak hanya merusak tekstur permukaan tanah, tapi juga beresiko menyebabkan infeksi saluran pernafasan akut (ISPA), jantung dan kanker. Ecobrick menjadi salah satu alternatif metode penanganan sampah plastik ramah lingkungan. Tujuan pengabdian adalah untuk mengenalkan pengelolaan sampah berkelanjutan di lingkungan sekolah melalui ecobrick. Pelatihan ini dilakukan menggunakan metode learning service, dengan memberikan pembelajaran polusi plastik di lingkungan dan pelatihan pembuatan ecobrick. Pada akhir pelatihan peserta diminta untuk mengisi kuesioner. Kegiatan diikuti oleh 40 siswa perwakilan kelas VIII SMP Islam Maarif 2 Sukun. Hasil pengabdian menunjukkan adanya peningkatan pengetahuan siswa tentang polusi plastik di lingkungan dan ecobrick sebagai alternatif mengurangi sampah plastik di lingkungan yang awalnya 57,5% menjadi 100%, 95% peserta berminat untuk memanfaatkan ecobrick dikemudian hari, 70% peserta ingin melanjutkannya sebagai peluang usaha. Peserta menilai kegiatan pengabdian dilaksanakan dengan sangat baik.
Peningkatan pemahaman pengelolaan koperasi bagi pengurus koperasi simpan pinjam dan pembiayaan syariah
Authors: Rofi’i Muhammad , Huda Nurul , Gani Ariel Nian , Hamdani Lukman , Rahmasuciana Dioni Yurinda
Published: December 2023

Pasca pandemi COVID-19, peran koperasi sangat dibutuhkan untuk mengembangkan modal bisnis UMKM. Dalam mengatasi masalah akses permodalan yang dialami UMKM, Kelompok Usaha Warung Sejahtera mendirikan koperasi pada awal 2022 bernama Koperasi Simpan Pinjam dan Pembiayaan Syariah Masyarakat Priok Berdaya. Pada awal pendirian koperasi, muncul masalah terkait kemampuan manajemen pengelolaan koperasi. Masalah perlu diselesaikan agar koperasi dapat mengelola pendanaan yang dibutuhkan UMKM. Tujuan yang ingin dicapai dari kegiatan pengabdian masyarakat ini adalah meningkatkan pengetahuan dan kemampuan anggota koperasi dalam mengelola koperasi. Metode yang digunakan dalam pengabdian masyarakat ini adalah Metode Participatory Action Research (PAR). Peserta dalam kegiatan ini berjumlah 35 orang. Berdasarkan hasil evaluasi, pada tahap pretest terdapat 15 pertanyaan yang harus dijawab oleh peserta, hasilnya menunjukkan bahwa peserta hanya mampu menjawab rata-rata 68,38%. pertanyaan dengan benar. Kemudian dilakukan posttest dengan 15 pertanyaan yang sama saat pretest, hasilnya menunjukkan bahwa semua peserta berhasil menjawab semua pertanyaan dengan benar (100%). Berdasarkan hasil pretest dan posttest tersebut, kegiatan pengabdian masyarakat ini memberikan kontribusi peningkatan pemahaman peserta sebesar 31,62% dalam memahami manajemen pengelolaan koperasi. Tindak lanjut yang diharapkan adalah pengurus koperasi dapat memaksimalkan kegiatan operasionalnya, menambah anggota baru, mengelola simpanan anggota, dan menyalurkan modal usaha kepada pelaku UMKM sehingga dapat meningkatkan kapasitas bisnisnya.
Program merawat jenazah untuk literasi zakat infak sedekah (ZIS)
Authors: Hidayatullah M.F. , Khotimah Khusnul , Rosyid Achmad Fathor
Published: December 2023

infak dan sedekah (ZIS) yang dikolaborasikan dengan dengan kegiatan pelatihan merawat jenazah. Kedua kegiatan ini penting mengingat literasi zakat memiliki pengaruh signifikan pada peningkatan penghimpunan zakat; pemahaman dan skill perawatan jenazah juga sangat diperlukan. Tulisan ini memaparkan hasil pengabdian masyarakat di 3 (tiga) Perumahan di Jember untuk meningkatkan literasi zakat yang dikolaborasikan dengan pelatihan merawat jenazah dengan pendekatan PAR (Participatory Action Research). Hasil dari kegiatan pengabdian ini, literasi zakat masyarakat semakin meningkat dan pemahaman merawat jenazah juga semakin tinggi. Tindak lanjut dari kegiatan ini, kegiatan diagendakan rutin dilaksanakan setiap tahun sekali, serta pendirian klinik zakat sebagai tempat konsultasi bagi muzakki.
Penguatan resilient pedagogy pada guru pos PAUD untuk optimalisasi tumbuh kembang anak usia dini
Authors: Muallifah  , Hasanah Siti Ma’rifatul , Khoirot Umdatul , Wafa Iqbal Ali , Ilmiah Habibatul , Agfian Difa
Published: December 2023

Anak usia dini memasuki masa golden age (masa emas) merupakan masa tumbuh kembang anak yang pesat dengan berbagai potensi awal yang dimiliki. Oleh karena itu, pada masa ini membutuhkan optimalisasi peran orangtua, guru dan lingkungan sekitar untuk mendukung melejitnya tumbuh kembang anak. Diantara cara yang bisa dilakukan adalah memberikan kualitas pembelajaran yang diberikan kepada anak usia dini, seperti yang sudah dilakukan Pos PAUD Kelinci kelurahan Samaan Kota Malang. Pos PAUD Kelinci. Kegiatan pengabdian ini bertujuan untuk mendampingi para guru Pos PAUD Kelinci memiliki kesadaran dan pemahaman pengajaran yang tangguh (relisient pedagogy), memahami tugas perkembangan anak serta optimalisasi potensi anak usia dini. Adapun kegiatan pengabdian dilaksanakan melalui metode Participatory Action Research (PAR) dengan 5 tahap, yakni: need assessment, merencanakan, pelatihan, evaluasi dan refleksi. Subjek penelitian dan pendampingan adalah guru-guru Pos PAUD Kelinci. Hasil kegiatan pengabdian adalah terbangunnya kesadaran dalam meningkatkan kualitas pengajaran dengan memperhatikan tugas perkembangan anak usia dini yang dibuktikan dengan tersusunnya modul tumbuh kembang anak usia dini berdasarkan tugas perkembangannya.
Pengaruh antioksidan Probucol terhadap kadar Malondialdehide (MDA) dan jumlah “Circulating Endothel Cells” pada tikus putih yang menerima stressor
Authors: Maslachah Lilik , Sugihartuti Rahmi , Agus Sudjarwo Sri
Published: December 2023

The obyective of the study was to find out the effect of Probucol as an antioxidant on Malondialdehyde (MDA) level and total circulating endothelial cells of rats exposed to stressor.This study was a post test only control group design using 35 three- months old male wistar rats devided into 5 groups consisting of 7 rats each namely the control groups (Po1, Po2) and the experiment groups (P1,P2, P3). Details of the treatment to each groups ere as follows:Group Po1 were given per oral Probucol dilution solution for 3 weeksGroup Po2 were given per oral Probucol dilution solution and stressor for 3 weeks Group P1 were given per oral Probucol dose I (5 mg/rat) and stressor for 3 weeksGroup P2 were given per oral Probucol dose II (10 mg/rat) and stressor for 3 weeks, andGroup P3 were given per oral Probucol dose III (20 mg/rat) and stressor for 3 weeksMalondialdehyde (MDA) level and total circulating endothelial cells were measured using “Buege and Aust (1978) and Hladovic and Rossman (1973)“ method modified by Wijayanto  (1996). Data on MDA level and total circulating endothelial cells were analyzed by using analysis of variant (Anova). The presence of significant difference was confirmed by using LSD test. Correlation between MDA level and total circulating endothelial cells was analysed by using “scarter plot” and r (rho) tests. The results showed a significant increase of MDA level of Po1 compared to Po2 (P less than 0.05). Significant decrease of MDA level (P less than 0,05) was observed in group  P1, P2 and P3 compared to that of the Po1 and Po2 control groups. The results also showed a significant increase of total circulating endothelial cells of the control group  Po1 compared to that in the control group Po2 (P less than 0,05), while significant decrease of total circulating endothelial  cells (P less than 0,05) was observed in group P1, P2 and P3 compared to that of the control group Po2. It can be concluded that stressor may increase MDA level and total circulating endothelial cells
Effects of Minor Alloying Elements (Cr and Mo) on the Corrosion Behaviors of API Grade Steel in CO2-Saturated Brine Environments
Authors: Yun Duck Bin , Bang Hye Rin , Kim Wan Keun , Kim Sung Jin
Published: December 2023

This study examined the effects of minor alloying elements (Cr and Mo) on the corrosion behaviors of API grade steel in CO2-saturated near-neutral aqueous solutions. Various experimental and analytical methods were applied to gain insights into the underlying CO2 corrosion mechanism of the steels. The findings revealed that steel with a minute quantity of Mo (0.1 ~ 0.15 wt%) exhibited the lowest corrosion current density and the highest polarization resistance. This outcome can be primarily attributed to the formation of a thin layer of Mo-based oxides/hydroxide, covered with a fine FeCO3 scale, consequently enhancing corrosion resistance in CO2 environments. On the other hand, the addition of Cr (0.4 ~ 0.5 wt%) in combination with Mo resulted in degraded corrosion resistance due to the competitive precipitation of amorphous Cr(OH)3 and crystalline FeCO3. This led to an uneven interface and the growth of FeCO3 particles, consequently reducing polarization resistance and increasing the corrosion rate. Based on the obtained results, it is recommended that cost-effective steels for CO2 transportation can be developed by adding a small amount of Mo along with a higher quantity of Cr. This optimized combination of alloying elements is expected to significantly improve the anti-corrosion performance of the steel in near-neutral brine environments with CO2.
The Windmill Row Theatre and the Irish (1796–1804): Civilizing Sydney Cove’s Convict Society
Authors: Kuch Peter
Published: December 2023

This essay examines the role of the Irish, and the performance of Irishness, in the Windmill Row Theatre (1796–1804), which opened a mere eight years after the penal colony of Sydney Cove was established. Influenced by revisionist histories such as Grace Karskens’ The Colony: A History of Early Sydney (2010), and by recent research about the performativity of Irishness on the eighteenth-century London and Dublin stages, it enriches the view that the colony was intended to be ‘a society, not a gaol’. While it offers a corrective to the idea that Sydney Cove was ‘a subsistence colony that would transform felons into farmers’, it takes issue with Robert Jordan's argument in The Convict Theatres of Early Australia (2002) that the theatre would have had little impact on the Irish. It proposes that several plays that were staged constituted a social experiment to manage the gender imbalance in the colony, and also considers the impact of Irish political protest, the role of the 1798 Rising and the effect of the contentious ‘Union of Hearts’ of 1800 on the theatre. It further speculates about Irish convict access to Australia's first commercial theatre, which had its own specifically designed building, booking system, regime of admission prices, and paid staff and actors.
The Life and Art of Mary Parks Washington (Fall 2018)
Authors: Porco Alessandro
Published: December 2023

This essay presents a critical biography of African American visual artist Mary Parks Washington, with an emphasis on her creative development from 1942 to 1979. Washington's extant art is discussed in the context of her educational background, social network, and political affiliations, as well as the history of activist curation in the wake of the Black Arts and Black Power movements. As an undergraduate at Spelman College in the 1940s, Washington was mentored by muralist Hale Woodruff, who encouraged her to continue her studies at the Art Students League of New York, Black Mountain College, and the Universidad Nacional de México. These experiences introduced Washington to key figures of the international and American avant-gardes, including Josef Albers, Diego Rivera, and Jacob Lawrence. In 1958, Washington settled down with her family in the Bay Area, where she met poet Sarah Webster Fabio, a leading figure in the Black Arts Movement on the West Coast. Washington and Fabio's collaborative friendship over two decades culminated in 1979's Offshoots of Roots Unknown, a series of “poem-paintings” that elegize Washington's family in early twentieth century Atlanta and, formally, deal with the technical (and ethical) problem of remembering and representing history. Drawing extensively on archival materials from the Auburn Avenue Research Library on African American Culture and History, this essay recognizes Washington's contribution to post-WWII African American art and documents her unique artistic trajectory, traversing aesthetic, social, and political formations from pre-Civil Rights Atlanta to the post-Black Arts Movement Bay Area.
Penerapan SMOTE-NCL untuk Mengatasi Ketidakseimbangan Kelas pada Klasifikasi Penyakit Jantung Koroner
Authors: Dewi Mariana , Saragih Triando Hamonangan , Herteno Rudy
Published: December 2023

Penyakit jantung koroner (PJK) terjadi akibat penyumbatan atau penyempitan pada pembuluh darah jantung karena adanya endapan lemak dan kolesterol sehingga mengakibatkan suplai darah ke jantung menjadi terganggu. PJK masih merupakan masalah kesehatan yang penting dan berdampak secara sosioekonomi karena biaya obat-obatan yang cukup mahal dan lamanya waktu perawatan serta pengobatannya. Upaya pencegahan melalui deteksi dini dan upaya pengendaliannya sangat penting untuk dilakukan. Salah satu cara untuk mendeteksi penyakit jantung koroner dengan memanfaatkan teknologi komputasi, yaitu melakukan klasifikasi menggunakan algoritma tertentu. Pada penelitian ini dilakukan klasifikasi dengan menggunakan algoritma Support Vector Machine (SVM) serta penanganan ketidakseimbangan data menggunakan SMOTE dan SMOTE-NCL. Data yang digunakan dalam penelitian ini adalah data Coronary Heart Disease yang memiliki dua buah kelas, yaitu kelas 0 (negatif PJK) dan kelas 1 (positif PJK) dengan permasalahan data yang tidak seimbang. Penelitian ini dilakukan dengan membandingkan kinerja dari klasifikasi SVM tanpa dilakukan penyeimbangan data, klasifikasi SVM dengan penyeimbangan data SMOTE, dan kalsifikasi SVM dengan penyeimbangan data SMOTE-NCL. Hasil yang didapatkan dari penelitian ini adalah pada klasifikasi SVM dengan penyeimbangan data SMOTE-NCL menghasilkan kinerja terbaik jika dibandingkan dengan model klasifikasi lain dengan nilai akurasi sebesar 85,10%.
Sistem Pendukung Keputusan untuk Menentukan Harga Bahan Pokok Menggunakan Regresi Linier
Authors: Widyastuti Ratna Widyastuti
Published: December 2023

Pemerintah Kota Kediri telah menyediakan aplikasi yang mampu memberikan update harga bahan pokok pada pasar-pasar tradisional setiap hari. sehingga masyarakat berusaha untuk dapat mengoperasikan teknologi berbasis web maupun maupun mobile untuk dapat mengakses aplikasi tersebut. Hal ini berguna bagi masyarakat untuk mendapatkan update harga bahan pokok terbaru yang dibutuhkan. Setelah mendapatkan harga bahan yang dibutuhkan pada setiap pasar masyarakat masih melakukan perhitungan untuk memperoleh biaya transportasi termurah berdasarkan lokasi masyarakat ke pasar. Hal ini menyulitkan masyarakat karena masyarakat harus melakukan perhitungan untuk membandingkan biaya perolehan bahan pokok berdasarkan update harga pada aplikasi dan perhitungan manual untuk biaya transportasi yang dapat diukur dengan jarak. Pengembangan aplikasi yang sudah ada dibutuhkan agar dapat memberikan rekomendasi biaya perolehan bahan pokok terendah berdasarkan harga kebutuhan pokok dan jarak lokasi. Dengan demikian masyarakat akan mendapatkan rekomendasi harga terendah terhadap bahan pokok yang dibutuhkan. Pengembangan aplikasi berbasis website dilengkapi dengan Sistem Pendukung Keputusan yang dapat memberikan rekomendasi perolehan bahan pokok dengan biaya terendah yang memperhitungkankan dua variabel yaitu jarak dan harga bahan pokok. Penggunaan metode regresi linier dibutuhkan untuk mendapatkan nilai terendah dari dua variabel yang telah ditentukan koefisiennya yaitu 70 persen untuk jarak dan 30 persen untuk harga.
Menganalisis Pola Deforestasi Hutan Lindung di Sulawesi Tenggara Menggunakan Metode K-Means
Authors: Ika Febryanti Wa Ode , Adiningsi Sri , Saputra Rizal Adi
Published: December 2023

Penelitian ini bertujuan untuk menganalisis pola deforestasi di wilayah hutan lindung di Sulawesi Tenggara menggunakan metode fuzzy k-means. Hutan di Indonesia diakui sebagai salah satu paru-paru dunia yang memberikan oksigen dan menyerap karbon dioksida. Namun, deforestasi terus terjadi di berbagai wilayah, termasuk di Sulawesi Tenggara. Metode fuzzy k-means digunakan dalam penelitian ini untuk mengidentifikasi pola-pola deforestasi yang kompleks dan memahami faktor-faktor yang mempengaruhi deforestasi di wilayah tersebut. Data tentang luas hutan lindung, data historis tentang deforestasi, dan faktor-faktor lain yang berpotensi mempengaruhi deforestasi dikumpulkan dan dianalisis. Hasil dari metode fuzzy k-means menunjukkan adanya pemisahan yang cukup baik antara wilayah hutan lindung yang rentan terhadap deforestasi dan wilayah yang memiliki potensi deforestasi yang rendah. Nilai pembobotan yang diberikan pada setiap wilayah menggambarkan tingkat kemungkinan deforestasi. Evaluasi menggunakan metrik seperti Silhouette Coefficient, Davies-Bouldin Index, dan Calinski-Harabasz Index menunjukkan bahwa klasterisasi yang dilakukan memiliki pemisahan yang baik antara klaster dengan penyebaran dan ukuran klaster yang kompak. Penelitian ini memberikan pemahaman yang lebih dalam tentang tingkat deforestasi di wilayah hutan lindung di Sulawesi Tenggara dan memberikan dasar untuk pengambilan keputusan yang lebih efektif dalam pengelolaan hutan lindung. Namun, hasil penelitian ini juga menekankan perlunya peningkatan pemantauan, perlindungan dan pengelolaan berkelanjutan, partisipasi masyarakat, kolaborasi antara pemangku kepentingan, serta penelitian lanjutan untuk meningkatkan pemahaman kita tentang deforestasi di wilayah ini.
Sistem Pakar Diagnosa Penyakit Tanaman Buncis di Kelompok Tani Dabalulik Desa Kabuna Berbasis Web
Authors: Lelo Yeremias , Mau Sisilia Daeng Bakka , Sinlae Alfry Aristo Jansen
Published: December 2023

Hasil produksi tanaman buncis di Kelompok Tani Dabalulik Desa Kabuna kurang stabil selama periode 2017 – 2021. Hal ini disebabkan oleh berbagai penyakit yang sering menyerang tanaman buncis yakni Layu, Bercak Daun, Busuk Lunak, Karat,Ujung Keriting. Dari permasalahan yang ada maka perlu untuk membangun sebuah aplikasi sistem pakar diagnosa tanaman buncis di Kelompok Tani Dabalulik Desa Kabuna berbasis web yang dapat membantu petani mendiagnosis penyakit pada tanaman buncis. Metode yang digunakan adalah metode Forward Chaining, metode ini dapat bekerja untuk mendapat solusi yang mengikuti fakta. Membangun suatu aplikasi menggunakan bahasa pemrograman PHP dan Database MySql. Metode yang digunakan dalam pengembangan sistem aplikasi adalah metode Expert System Life Cycle yang merupakan salah satu metode dalam   sistem pakar yang dihasilkan dapat membantu para petani mendiagnosa penyakit pada tanaman buncis dan memberikan informasi mengenai penyakit dan gejala – gejala pada buncis agar terhindar dari penyakit tanpa harus menunggu datangnya pakar. Aplikasi konsultasi berbasis web ini mampu mendiagnosa penyakit pada buncis serta memberikan solusi untuk menangani penyakit yang sering terjadi pada tanaman buncis yang pada akhirnya dapat mengurangi penyakit pada tanaman buncis yang sering terjadi di Kelompok Tani Dabalulik Desa Kabuna.
Game Pembelajaran Huruf Jepang Menggunakan Algoritma Fisher-Yates Shuffle
Authors: Marcellio Vincent , Hermawan Latius
Published: December 2023

Kemajuan teknologi di masa kini yang semakin berkembang pesat berpengaruh pada keefektifan, kemajuan, dan kepraktisan bagi pelajar dalam mempelajari bahasa baru. Pada studi kasus ini, lembaga kursus Shimeta Education Center Palembang yang memiliki bahasa Jepang sebagai salah satu mata pelajarannya belum memiliki perangkat lunak yang dapat membantu keefektifan siswa dalam mempermudah mengingat hurur-huruf Jepang yang tentu sangat baik apabila ada suatu metode yang dapat membantu para murid pada lembaga kursus ini mengingat huruf-huruf tersebut dengan cara yang menyenangkan serta efektif. Dengan ini dibuatlah game yang dapat membantu para murid mengingat huruf-huruf Jepang tersebut dengan cara yang menarik serta efektif. Pada game diterapkan sebuah algoritma pengacak fisher-yates shuffle pada soal yang berguna untuk mengacak soal-soal yang ada pada game agar game memiliki tantangan dikarenakan soal-soal yang selalu berubah setiap saat. Kesimpulan dari penelitian ini adalah game berhasil dibangun menggunakan Unity3D dan algoritma fisher-yates shuffle berhasil diterapkan pada game serta 96,7% responden merasa senang setelah bermain game ini.
Finite State Machine in Chatbot Line E-Commerce Design Using NodeJs MongoDb and Express
Authors: Pribadi Farid Angga , Firdausi Annisa Taufika , Arhandi Putra Prima
Published: December 2023

Perkembangan ilmu pengetahuan dan teknologi di bidang teknologi informasi mengakibatkan terjadinya perubahan perilaku pengguna di internet. Saat ini media sosial mengambil peranan penting dalam pemasaran dan penjualan. Salah satu sosial media yang populer di indonesia adalah line messenger. Line memiliki fitur chatbot yang memungkinkan untuk membuat chat berbasis bot yang dapat dijalankan pada aplikasi line messenger. Namun terdapat kekurangan pada chatbot yaitu manajemen menu dan fungsi yang ditampilkan ke user tidak termanajemen dengan baik. Masalah tersebut dapat diselesaikan dengan menggunakan finite state machine. Metode finite state machine digunakan untuk menentukan alur pengguna saat memilih menu yang tampil pada chatbot. Penelitian ini bertujuan untuk merancang dan membangun chatbot yang akan dimanfaatkan untuk penjualan dan pembelian serta menerapkan metode finite state machine untuk manajemen menu yang ditampilkan pada chatbot. Model pengembangan Software development life cycle (SDLC) yang digunakan adalah model Rapid Application Development (RAD). RAD memiliki beberapa tahapan yaitu analisa (analysis), perancangan (design), implementasi (implementation), pengujian (testing), pemeliharaan (maintenance). Pada penelitian ini dilakukan dua jenis pengujian, yang pertama pengujian finite state, pengujian dilakukan dengan melakukan input terhadap state chatbot dan membandingkan response chatbot dengan hasil yang diharapkan. Yang kedua Usability Testing yaitu pengujian dilakukan menggunakan kuisoner Computer System Usability Questionnaire (CSUQ). Hasil penelitian ini menujukkan bahwa 87% pengguna dapat dengan mudah untuk menggunakan sistem chatbot yang digunakan untuk penjualan dan pembelian serta metode finite state machine dapat menampilkan menu sesuai state yang ditentukan.
Pengembangan Augmented Reality Marketing (ARM) Menggunakan Algoritma Fast Corner Sebagai Media Promosi Produk Furniture Pelaku Usaha
Authors: Yusupa Ade
Published: December 2023

Augmented Reality marketing (ARM) merupakan teknologi yang mengkombinasikan benda maya baik itu berbentuk 2 dimensi( 2D) atau 3 dimensi( 3D) ke dalam suatu area jelas dalam penggunaan penjualan produk. Aplikasi Augmented Reality( AR) ini dibuat memanfaatkan penanda (marker) sebagai pemicu (trigger) guna menunjukkan produk furniture. Aplikasi yang dipakai untuk pembuatan aplikasi ialah Unity dengan Vuforia serta untuk objek 3D memakai aplikasi Blender. Metode yang akan diterapkan berupa metode waterfall dalam pengembangan Aplikasi Furniture ARM peningkatan dengan algoritma fast corner dengan menggunakan nilai pixel pada objek menampilkan produk Furniture dalam wujud 3D. Pada prosedur scan AR jarak minimun marker dengan kamera ponsel pintar ialah 10 centimeter serta maksimum 160 centimeter, dengan sudut kemiringan 30, 45, 60, serta 90 bagian. Hasil pengetesan itu pula dipengaruhi oleh algoritma fast corner dengan menggunakan nilai pixel pada objek, semakin jauh jarak kamera ataupun pixel pada kamera, hingga nilai pixel itu tidak terdeteksi serta objek tidak bisa terdeteksi. Intensitas sinar pula mempengaruhi dalam cara scan AR, pada ruangan terang serta redup aplikasi bisa menunjukkan produk furniture, sebaliknya pada ruangan gelap tidak bisa diperlihatkan. Nilai delay amat mempengaruhi kepada Intensitas sinar serta jarak, dimana diperoleh angka delay terkecil pada ruangan cerah serta delay terbesar pada ruangan redup, setelah itu semakin jauh jarak antara marker dengan ponsel pintar hingga semakin besar angka delaynya. Dengan memakai pengujian Mean Opinion Score, diharapkan didapat hasil angka MOS terbaik, Furniture 3D yang diperlihatkan serta Aplikasi Furniture AR amat sesuai selaku alat promosi produk furniture, menunjang para pelaku usaha di kota manado dalam memudahkan promosi hasil produksi.
Rancang Bangun Aplikasi Monitoring Mesin Produksi Menggunakan Metode PIECES
Authors: Ibrahim Ilham , Batubulan Kadek Suarjuna , Yunianto Dika Rizky
Published: December 2023

Studi ini menyajikan pengembangan aplikasi pemantauan mesin produksi menggunakan metode PIECES (Performance, Information, Economy, Control, Efficiency, and Service). Tujuan utamanya adalah untuk meningkatkan keandalan, kinerja, dan keamanan sistem, sambil mempertimbangkan variabel ekonomi untuk memberikan solusi yang hemat biaya bagi perusahaan. Sistem ini dirancang dengan kontrol yang tepat dan tindakan keamanan untuk mencegah akses yang tidak sah dan memastikan integritas sistem. Kinerja sistem dioptimalkan, menghasilkan efisiensi yang lebih baik dalam proses produksi. Penerapan metode PIECES menghasilkan sistem yang andal, memungkinkan pengambilan keputusan yang lebih cepat dan akurat. Studi ini menunjukkan bahwa metode PIECES adalah pendekatan yang efektif untuk mengembangkan dan mengimplementasikan sistem pemantauan mesin produksi.
Gender still determines how, and how long, we work
Authors: Schmitz Wiebke
Published: December 2023

Female-coded family work keeps women away from late working life – but it makes a difference where in Europe they live because Nordic countries do not recognize this divide. Key Findings Childcare impacts upon late working life – women tend to be employed part time or outside paid labor if they engaged in childcare during earlier life stages; men with children are more likely to be in full-time employment. Women are more affected by early working life decisions – previous labor-market participation or a reduction in working hours due to childcare obligations have a greater impact on late working life. A North–South divide in Europe – it is mostly in southern and western Europe that women’s domestic work or part-time employment prevents full-time employment in late working life, but in northern Europe, female employment in late working life is barely affected by previous family obligations. This research on gendered late-working-life trajectories is part of the research programme EIWO. Schmitz, W., Naegele, L., Frerichs, F., & Ellwardt, L. (2023): Gendered late working life trajectories, family history and welfare regimes: Evidence from SHARELIFE. European Journal of Ageing, 20, 5. https://doi.org/10.1007/s10433-023-00752-3 (open access). The paper received the "Best Paper Award 2023 for Early Career Researchers" from the German Gerontological Association (see https://www.dggg-online.de/best-paper-award.html).
Methoxychlor induces oxidative stress and impairs early embryonic development in pigs
Authors: Geng Zhaojun , Jin Yongxun , Quan Fushi , Huang Siyi , Shi Shuming , Hu Bing , Chi Zhichao , Kong Ilkeun , Zhang Mingjun , Yu Xianfeng
Published: December 2023

Introduction: Methoxychlor (MXC) is an organochlorine pesticide (OCP) that was formerly used worldwide as an insecticide against pests and mosquitoes. However, MXC is not biodegradable and has lipophilic characteristics; thus, it accumulates in organisms and affects reproductive function. MXC, as an estrogenic compound, promotes oxidative stress, induces oxidative stress damage to ovarian follicles, and causes miscarriages and stillbirths in females. In this research endeavor, our primary objective was to explore the ramifications of MXC regarding the developmental processes occurring during the initial stages of embryogenesis in pigs.

Methods: In this study, we counted the blastocyst rate of early embryos cultured in vitro. We also examined the reactive oxygen species level, glutathione level, mitochondrial membrane potential, mitochondrial copy number and ATP level in four-cell stage embryos. Finally, apoptosis and DNA damage in blastocyst cells, as well as pluripotency-related and apoptosis-related genes in blastocyst cells were detected. The above experiments were used to evaluate the changes of MXC damage on early parthenogenetic embryo development.

Results and Discussion: The results showed that early embryos exposed to MXC had a significantly lower cleavage rate, blastocyst rate, hatching rate, and total cell count compared with the control group. It was also of note that MXC not only increased the levels of reactive oxygen species (ROS), but also decreased the mitochondrial membrane potential (ΔΨm) and mitochondrial copy number during the development of early embryos. In addition, after MXC treatment, blastocyst apoptosis and DNA damage were increased, decreased cell proliferation, and the expression of pluripotency-related genes SOX2, NANOG, and OCT4 was down-regulated, while the expression of apoptosis-related genes BAX/BCL-2 and Caspase9 was up-regulated. Our results clearly show that MXC can have deleterious effects on the developmental processes of early porcine embryos, establishing the toxicity of MXC to the reproductive system. In addition, the study of this toxic effect may lead to greater concern about pesticide residues in humans and the use of safer pesticides, thus potentially preventing physiological diseases caused by chemical exposure.
Virulence-related genotypic differences among Bacillus cereus ocular and gastrointestinal isolates and the relationship to endophthalmitis pathogenesis
Authors: Coburn Phillip S. , Miller Frederick C. , LaGrow Austin L. , Mursalin Huzzatul , Gregory Anna , Parrott Aaron , Astley Daniel , Callegan Michelle C.
Published: December 2023

Background

Bacillus cereus (Bc) can cause self-limiting gastrointestinal infections, but when infecting the eye, can cause rapid and irreversible blindness. This study investigated whether clinical ocular and gastrointestinal Bc isolates differed in terms of virulence-related genotypes and endophthalmitis virulence.

Methods

Twenty-eight Bc ocular, gastrointestinal, and laboratory reference isolates were evaluated. Hemolysis assays were performed to assess potential differences in hemolytic activity. The presence of twenty Bc virulence-related genes was assessed by PCR. A subset of ocular and gastrointestinal isolates differing in PCR positivity for 5 virulence genes was compared to strain ATCC14579 in an experimental murine model of endophthalmitis. At 8 hours post infection, retinal function was evaluated by electroretinography, and intraocular bacterial concentrations were determined by plate counts.

Results

Gastrointestinal Bc isolates were more hemolytic than the Bc ocular isolates and ATCC14579 (p < 0.0001). Bc ocular isolates were more frequently PCR-positive for capK, cytK, hblA, hblC, and plcR compared to the gastrointestinal isolates (p ≤ 0.0002). In the endophthalmitis model, mean A-wave retention did not differ significantly between eyes infected with ATCC14579 and eyes infected with the selected ocular or gastrointestinal isolates (p ≥ 0.3528). Similar results were observed for mean B-wave retention (p ≥ 0.0640). Only one diarrheal isolate showed significantly greater B-wave retention when compared to ATCC14579 (p = 0.0303). No significant differences in mean A-wave (p ≥ 0.1535) or B-wave (p ≥ 0.0727) retention between the selected ocular and gastrointestinal isolates were observed. Intraocular concentrations of ATCC14579 were significantly higher than the selected ocular isolate and 3 of the gastrointestinal isolates (p ≤ 0.0303). Intraocular concentrations of the selected ocular isolate were not significantly different from the gastrointestinal isolates (p ≥ 0.1923).

Conclusions

Among the subset of virulence-related genes assessed, 5 were significantly enriched among the ocular isolates compared to gastrointestinal isolates. While hemolytic activity was higher among gastrointestinal isolates, retinal function retention and intraocular growth was not significantly different between the selected ocular and gastrointestinal isolates. These results suggest that Bc strains causing gastrointestinal infections, while differing from ocular isolates in hemolytic activity and virulence-related gene profile, are similarly virulent in endophthalmitis.
Prognostic value of optical flow ratio for cardiovascular outcomes in patients after percutaneous coronary stent implantation
Authors: Hu Tianyu , Qiu Qinghua , Xie Nianjin , Sun Mingming , Jia Qianjun , Huang Meiping
Published: December 2023

Background

The relationship between the optical flow ratio (OFR) and clinical outcomes in patients with coronary artery disease (CAD) after percutaneous coronary stent implantation (PCI) remains unknown.

Objective

To examine the correlation between post-PCI OFR and clinical outcomes in patients with CAD following PCI.

Methods

Patients who underwent optical coherence tomography (OCT) guided PCI at Guangdong Provincial People's Hospital were retrospectively and continuously enrolled. Clinical data, post-PCI OCT characteristics, and OFR measurements were collected and analyzed to identify predictors of target vessel failure (TVF) after PCI.

Results

Among 354 enrolled patients, 26 suffered TVF during a median follow-up of 484 (IQR: 400–774) days. Post-PCI OFR was significantly lower in the TVF group than in the non-TVF group (0.89 vs. 0.93; P = 0.001). In multivariable Cox regression analysis, post-PCI OFR (HR per 0.1 increase: 0.60; 95% CI: 0.41–0.89; P = 0.011), large stent edge dissection (HR: 3.85; 95% CI: 1.51–9.84; P = 0.005) and thin-cap fibroatheroma (TCFA) (HR: 2.95; 95% CI: 1.19–7.35; P = 0.020) in the non-stented segment were independently associated with TVF. In addition, the inclusion of post-PCI OFR to baseline characteristics and post-PCI OCT findings improved the predictive power of the model to distinguish subsequent TVF after PCI (0.838 vs. 0.796; P = 0.028).

Conclusion

The post-PCI OFR serves as an independent determinant of risk for TVF in individuals with CAD after PCI. The inclusion of post-PCI OFR assessments, alongside baseline characteristics and post-PCI OCT findings, substantially enhances the capacity to differentiate the subsequent manifestation of TVF in CAD patients following PCI.
Comprehensive review on gene mutations contributing to dilated cardiomyopathy
Authors: Wang Shipeng , Zhang Zhiyu , He Jiahuan , Liu Junqian , Guo Xia , Chu Haoxuan , Xu Hanchi , Wang Yushi
Published: December 2023

Dilated cardiomyopathy (DCM) is one of the most common primary myocardial diseases. However, to this day, it remains an enigmatic cardiovascular disease (CVD) characterized by ventricular dilatation, which leads to myocardial contractile dysfunction. It is the most common cause of chronic congestive heart failure and the most frequent indication for heart transplantation in young individuals. Genetics and various other factors play significant roles in the progression of dilated cardiomyopathy, and variants in more than 50 genes have been associated with the disease. However, the etiology of a large number of cases remains elusive. Numerous studies have been conducted on the genetic causes of dilated cardiomyopathy. These genetic studies suggest that mutations in genes for fibronectin, cytoskeletal proteins, and myosin in cardiomyocytes play a key role in the development of DCM. In this review, we provide a comprehensive description of the genetic basis, mechanisms, and research advances in genes that have been strongly associated with DCM based on evidence-based medicine. We also emphasize the important role of gene sequencing in therapy for potential early diagnosis and improved clinical management of DCM.
Effect of balloon pulmonary angioplasty on cardio-ankle vascular index and biventricular remodeling in patients with chronic thromboembolic pulmonary hypertension
Authors: Sato Shuji , Ito Takuro , Tabata Tsuyoshi , Ogawa Akihiro , Saiki Atsuhito , Shimizu Kazuhiro
Published: December 2023

Background

Chronic thromboembolic pulmonary hypertension (CTEPH) is caused by organized pulmonary thrombi, and pulmonary endarterectomy is the only curative treatment. Since balloon pulmonary angioplasty (BPA) has become an established therapeutic option for inoperable CTEPH, prognosis has improved. Recent reports suggest that arterial stiffness evaluated using the cardio-ankle vascular index (CAVI) may play an important role in the cardio-vascular interaction in CTEPH; however, the details remain unclear. This study aimed to clarify the role of CAVI in CTEPH through hemodynamic changes and ventricular remodeling after BPA.

Methods and results

A total of 23 patients with CTEPH who had undergone BPA were enrolled in this study. The mean pulmonary artery pressure (mPAP) and CAVI significantly decreased after BPA [mPAP, 34 (26–45) mmHg to 20 (19–24) mmHg, p < 0.0001; CAVI, 9.4 (8.0–10.3) to 8.3 (7.5–9.6), p = 0.004]. The echocardiographic right ventricle was significantly decreased, and the left ventricular volume was significantly increased after BPA, indicating significant biventricular remodeling after BPA. Changes in CAVI (ΔCAVI) significantly correlated with changes in mPAP (r = 0.45, p = 0.03). Additionally, ΔCAVI was significantly correlated with changes in both right ventricular area and left ventricular volume.

Conclusions

Arterial stiffness, evaluated using the CAVI, improved after BPA. Changes in CAVI were significantly correlated with changes in pulmonary arterial pressure and biventricular remodeling. CAVI may play an important role in cardiovascular interactions in patients with CTEPH.