bluuebunny/crossref_metadata_2025 huggingface dataset:
MELANOMA EM REGRESSÃO E NEVO HALO
Authors: Campos e Campos Maria das Graças Sepúlveda , Maceira Juan Piñeiro , Neves René Garrido
Published: July 2023

O nevo halo e o melanoma com áreas de regressão por compartilharem algumas características clínicas, histopatológicas, imunológicas e evolutivas, permitem comparações, e servem de modelo de estudo dos mecanismos de involução espontânea nas lesões melanocíticas benignas e malignas, um fenômeno muito investigado, porém não completamente esclarecido.
Editorial
Authors: Duarte Shaytner Campos
Published: July 2023

A Evolução da Saúde na Internet

A OMS (Organização Mundial de Saúde) define saúde como “um estado de completo bem-estar físico, mental e social e não somente ausência de doenças”. A saúde, portanto, é um direito social, inerente à condição de cidadania, que deve ser assegurado sem distinção de raça, religião, ideologia política e condição socioeconômica.

Em uma publicação da ano de 2000 para o “Encontro Internacional: direito à saúde, cobertura universal e integralidade possível”, a ONU (Organização das Nações Unidas) reforça esse conceito, assinalando quatro condições mínimas para que um Estado assegure o direito à saúde aos seus cidadãos: disponibilidade financeira, acessibilidade, aceitabilidade e qualidade do serviço de saúde pública do país.

Além dos próprios serviços de saúde, as mídias impressas, depois a TV e hoje a internet assumiram papel importante na conscientização da população e no apelo às mobilizações em conjunto e às responsabilidades individuais. Por meio da troca de informações a respeito de temas complexos, há algumas décadas pessoas que possuem uma enfermidade específica ou um problema de saúde em comum constituíram associações que unem os pares e profissionais da área de saúde e direito.

As novas mídias, disponíveis pela internet, trazem possibilidades de interação nunca antes experimentadas, eliminam obstáculos físicos e temporais e apresentam espaço para novas formas de mobilização social, garantindo maior alcance de informações essenciais à sociedade no que diz respeito à sua saúde, como políticas de planejamento, prevenção, conscientização dos direitos etc.

Com intenção de manter o bom estado de saúde de todos e alertar para os principais problemas que podem atingir a população mundial, a OMS, em 1948, criou o Dia Mundial da Saúde, celebrado todo dia 7 de abril, desde então. O tema do dia mundial da saúde de 2018 foi “Saúde para todos”.

A Revista Científica da Faculdade de Medicina de Campos – RCFMC, conclui, com imenso regozijo, mais um fascículo. Criada em 2006, a RCFMC possui periodicidade semestral e sua maior preocupação é estimular a produção científico-tecnológica, e o debate acadêmico de discentes e docentes, além de instigar a difusão da pesquisa nas diversas áreas da Saúde. Dessa forma, atua como um ambiente virtual interdisciplinar para a apresentação e divulgação dos trabalhos desenvolvidos por pesquisadores locais, regionais e nacionais.

 Desejo a todos uma ótima leitura.

 Shaytner Campos Duarte

Editor Chefe
ASPECTOS GERAIS SOBRE A DOR NEUROPÁTICA
Authors: Terra Luma Costa , Marchiori Ana Cecília Pessini , Barreto Letícia Oliveira , Perez Pollyanna Rodrigues Guerra , Teixeira Anderson Nunes
Published: July 2023

Introdução: A dor propriamente dita remete aos seres vivos um caráter protetor, e de fato é um mecanismo vital à sobrevivência. As informações nociceptivas provenientes de algum dano tecidual comumente são reversíveis e geram uma hipersensibilidade protetora ao local lesado durante o processo de cura. A dor neuropática é consequência de uma lesão nervosa, de difícil diagnóstico e tratamento complexo, muitas vezes ainda desconhecido. Por se tratar de uma condição nervosa, assim como muitas outras dores, é diretamente afetada pelo estado psíquico e emocional do paciente, sendo importante a análise dos mais diversos fatores antes do início do tratamento farmacológico.
Integrinas na adesão, migração e sinalização celular: associação com patologias e estudos clínicos.
Authors: Ferraz Francielle Bonet , Fernandez Jorge Hernandez
Published: July 2023

Integrinas são intermediadoras na comunicação entre o citoesqueleto celular e proteínas plasmáticas ou da matriz extracelular por meio da adesão célula-a-célula através de interações com outras proteínas de membrana. Além da função de adesão, as integrinas são reconhecidas moléculas de sinalização capazes de realizar a transdução de mensagens por vias de sinalização clássica, graças a sua estrutura molecular. Desse modo, as integrinas podem ser consideradas moduladores chave da proliferação, migração, longevidade, migração e ainda, a manutenção das funções específicas de diferenciação celular. Esta revisão aborda informações pertinentes de como as integrinas funcionam de modo complexo dentro de vias de sinalização, de adesão, do citoesqueleto e desempenham papel fundamental no sistema hematopoiético, especialmente no sistema imune. Como sistema complexo, qualquer falha oferece maiores oportunidades para o desenvolvimento de patologias. Desse modo, aberrações na sinalização mediada pelas integrinas podem contribuir para diferentes estados patológicos, como metástase, angiogênese e doenças inflamatórias. Por fim, são exemplificados alguns antagonistas de integrinas que estão envolvidos em estudos clínicos como novas terapias
BENEFÍCIOS DE UM PERIÓDICO INSTITUCIONAL
Authors: Duarte Shaytner
Published: July 2023

EDITORIAL
Cancer de Mama e Gestação: Relato de Caso e Revisão de Literatura.
Authors: Admin Admin
Published: July 2023

Relatamos e discutimos o caso de uma gestante portadora de Câncer de Mama. Objetiva-se compartilhar com a comunidade médica geral: o complexo desafio clínico de manusear adequadamente o caso relatado, além de apresentar informações científicas atuais referentes ao tema, pesquisadas em diferentes fontes de dados especializados, mediante uso de palavras-chave: câncer de mama; gestação; gravidez. Trata-se de uma pesquisa bibliográfica. Aprovada pelo Comitê de Ética em Pesquisas do Hospital Escola Álvaro Alvim, Campos dos Goytacazes, RJ. Não há conflitos de interesses (CFM, 1595/2000). Os dados foram analisados sistematicamente, tendo-se constantemente o foco no objetivo da pesquisa.
DIRETIVAS ANTECIPADAS DE VONTADE: A NECESSIDADE DE UM MAIOR CONHECIMENTO DESDE A GRADUAÇÃO
Authors: Gauw Juliana Holanda de , Albuquerque Ana Letícia Amorim de , Lins Ingrid Karoline Freitas Guedes , Chaves José Humberto Belmino
Published: July 2023

INTRODUÇÃO: Diretivas Antecipadas de Vontade (DAV) é um tema que se torna cada vez mais presente devido à transição epidemiológica que vive o Brasil e seu conseqüente aumento da prevalência dos cuidados paliativos. OBJETIVO: Este trabalho tem como objetivo conscientizar docentes e discentes sobre a importância do conhecimento das DAV devido sua extrema relevância ao bem estar do paciente, cuidados paliativos e terminalidade, e também como meio de defesa jurídica para os profissionais. MÉTODOS: Trata-se de uma revisão sistemática de literatura, sem meta-análise, que utilizou as seguintes bases de dados: Bireme, Medline, SciELO e Medscape, no recorte temporal de 2001 a 2016, com artigos que relacionam as diretivas antecipadas, educação médica e relação médico-paciente. RESULTADOS: Diversos trabalhos revelam significativo desconhecimento dos profissionais de saúde sobre este tema e sobre a Resolução do CFM 1995/2012. Observou-se também que grande parte das matrizes curriculares das universidades não apresenta as DAV no plano das disciplinas e que médicos com mais conhecimento sobre cuidados paliativos e terminalidade são os mais seguros a tomarem decisões benéficas aos pacientes. CONCLUSÃO: É fato a necessidade da introdução das DAV nos programas de graduação, visto que é mínimo o conhecimento sobre este tema, o que prejudica a relação médico-paciente, autonomia e o exercício da profissão com segurança e autonomia.
Sarcoma de Kaposi como diagnóstico diferencial de lesões vulvares: relato de caso e revisão bibliográfica
Authors: De Barros Carlos Eduardo Peçanha , Duarte Shaytner Campos , Shimoda Eduardo , Rodrigues Cristiano Salles , Cordeiro Kathelyn Ferreira
Published: July 2023

Os autores apresentam um caso de massa tumoral vulvar, em paciente soropositivo, localizada em sua maior extensão em região de monte púbico com extensão para pequeno lábio direito, medindo aproximadamente 10 cm. A paciente foi submetida à Biópsia da lesão, sendo revelado em estudo histopatológico Sarcoma de Kaposi. É uma doença sistêmica multifocal maligna, que tem origem no endotélio vascular e que tem uma evolução clínica muito variável. Este é um caso de apresentação rara da doença. Sua patogenia, seus aspectos clínicos, bem como seguimento terapêutico é também objeto de discussão no presente trabalho.
Púrpura Trombocitopênica Idiopática grave por Citomegalovírus
Authors: Cordeiro Leonardo Pessanha , De Almeida Velasco Leticia , Fraga Soares Juliana , Araujo Zulchner Marina
Published: July 2023

A Púrpura Trombocitopênica Idiopática (PTI) é uma condição autoimune caracterizada pela destruição plaquetária mediada por anticorpos, com maior prevalência na faixa etária pediátrica. O diagnóstico é de exclusão, demonstrando plaquetopenia isolada e sinais clínicos, como equimoses, menorragia e gengivorragia. O presente artigo evidencia um caso de PTI associada à infecção por citomegalovírus em um homem de 64 anos. O exame inicial evidenciou uma trombocitopenia de 5.000 10³/mm³ e suas manifestações eram hematoma em palato e em fossa cubital direita, além de púrpuras em membros superiores, inferiores e abdome, além de episódios de melena, hematúria e epistaxe. O tratamento com imunoglobulina humana e corticoterapia foi efetivo, evoluindo com elevação plaquetometria e redução dos hematomas. Visto que a plaquetopenia é uma alteração comum a diversas patologias, é necessário realizar o diagnóstico diferencial para que o tratamento seja iniciado o mais precoce possível de modo a de evitar a evolução para quadros hemorrágicos graves.
Metástase cerebral como manifestação clínica inicial de cancer de esôfago - raro Relato de Caso.
Authors: Barbosa Frederico Paes , Mendonça Sandro Bichara , Mendonça Gabriel Soares , Artiles Camila Burla
Published: July 2023

Relatamos um caso de Câncer de Esôfago, com rara manifestação clínica inicial: metástase cerebral. Inicialmente abordado neurocirurgicamente, com sucesso, o estudo histopatológico da peça operatória sinalizou para possível origem gastrintestinal. O qual foi histopatologicamente estudado, sendo identificado: neoplasia de esôfago distal avançada. Fundamentados em informações científicas atualizadas especializadas sobre o caso clínico, constatamos tratar-se de raro caso clínico com prognóstico bastante desfavorável para o doente. Entretanto, com acolhimento e tratamento clínico protocolar, ético, multiprofissional cauteloso: obtivemos melhores resultados clínicos para o doente, comparado às informações pesquisadas e registradas neste Relato de Caso. Esperamos ressaltar para a comunidade médica, de um modo geral, a complexidade com que as doenças oncológicas podem se apresentar e a necessidade de abordagens multiprofissionais clínicas protocolares éticas, compartilhadas tanto com o doente, quanto com seus familiares. Nestas condições, resultados inesperados podem ser alcançados.
Regina Célia de Souza Campos Fernandes
Authors: Campos Fernandes Regina Célia de Souza
Published: July 2023

Vol 7, nº1, 2012
PERSPECTIVA - Série “Desmistificando a ciência” Truvada®: A primeira quimioprofilaxia de pré-exposição aprovada contra a transmissão sexual do HIV
Authors: Medina-Acosta Enrique , Campos Fernandes Regina Célia de Souza
Published: July 2023

PERSPECTIVA - Série “Desmistificando a ciência”  Truvada®: A primeira quimioprofilaxia de pré-exposição aprovada contra a transmissão sexual do HIV.
Síndrome de Marfan Neonatal: Relato de Caso
Authors: Lobo Gabryelle  Pinheiro  , Souza Fernandes Regina Célia  de Campos  , De Moura Porto Erika  Ferreira 
Published: July 2023

Introdução: A  Síndrome  de Marfan  é  uma  desordem  rara,autossômica dominante que afeta o tecido conectivo, acometendoprincipalmente os sistemas esquelético, ocular e cardiovascular.Mutações no gene da fibrilina (FBN1) localizado no cromossomo15q21 são responsáveis pelos padrões de defeito observados naSíndrome de Marfan. O diagnóstico é feito de acordo com umarevisão dos critérios diagnósticos conhecida como a nosologia Ghent,por meio  de  uma  avaliação  de  critérios maiores  e menores.Objetivo: Relatar um caso de Síndrome de Marfan, forma neonatal.Métodos: Análise de prontuário médico, acompanhamento dapaciente e revisão da literatura.Relato de caso: Menor do sexo feminino, com queixa de cansaçoàs mamadas desde os 3 meses, foi hospitalizada aos 7 mesessendo estabelecido o diagnóstico de Síndrome de Marfan a partirda presença de sopro cardíaco, membros e dedos alongados,flacidez e hipermobilidade além de achado ecocardiográfico dedisplasia das válvulas mitral e tricúspide. Submetida a tratamentocirúrgico com boa evolução.Conclusão: O diagnóstico precoce é imprescindível para umamelhor abordagem terapêutica da Síndrome de Marfan e dependeda valorização de sinais e sintomas, concomitante ao conhecimentoprévio desta patologia rara.
COMPARISON OF WALKING PARAMETERS IN ADOLESCENT IDIOPATHIC SCOLIOSIS AND HEALTHY ADOLESCENTS
Authors: ALAZZAWI Ammar , Kaya Mehmet Hanifi , Büyükturan Buket , Büyükturan Öznur
Published: July 2023

This study was planned to evaluate gait differences in healthy adolescents with adolescent idiopathic scoliosis (AIS). In addition, it was aimed to evaluate the correlation between gait parameters and other variables of patients with
AIS. Forty adolescent individuals were included in the study. While 20 of these individuals were patients with AIS, 20 were healthy adolescents. In this study, gait analysis of each case was evaluated with Biodex Unweighing System
(Inc. Shirley, USA), spinal deformity perceptions with Walter Reed Visual Assessment Scale (WRVAS), self-perception of trunk deformity with Trunk Appearance Perception Scale (TAPS) , quality of life with Scoliosis Research Society-22
(SRS-22), and fear of movement was assessed with the Tampa Scale of Kinesiophobia (TSK). According to the results of our study; Compared to the healthy control group, subjects with AIS have been shown to differ significantly, they
had shorter duration of standing on one leg (p=0.028), shorter mean stride cycle (p=0.003), longer mean right stride length (p= 0.035), longer mean left stride length (p=0.039) and worse ambulation indices (p=0.036). In addition,
statistically significant correlations were found between Cobb angle and WRVAS and TAPS in the group with AIS, and between walking speed and age, One Leg Standing Time, TSK and stride cycle (p<0.05). As a result, it was determined
that some gait parameters of patients with AIS showed deviations from normal when compared to healthy adolescents.
Strategi Pengembangan Koperasi Melalui Kolaborasi dan Transformasi Digital di Kota Bogor
Authors: Wardhani Yustiana , Gerald Prasetya Syarief , Clara Simanjuntak Vera
Published: July 2023

The research aims to identify the influential factors in developing cooperative development strategies in the city of Bogor. Research data using primary data and analysis using quantitative methods with SWOT and AHP analysis. The results of the research on the internal-external (IE) matrix show that the position of cooperative development is in cell one by implementing a growth strategy through vertical integration, by means of backward integration, meaning that in order to develop cooperatives in Bogor City, they must be independent, which means the use of all factors of production rely on the cooperative's own business, both products, human resources and other resources. The results of AHP show that the most prioritized strategy implemented is a strategy of trying to improve information and technology systems so that they can innovate and compete with other similar businesses. Cooperatives can make efforts to increase cooperation with the government and the private sector in the field of science and technology development so that cooperatives can innovate and compete in the market, as well as efforts to increase public trust in cooperatives and the need to make regulations and policies that support the development of cooperatives.
Isolasi Cendawan Mikoriza Arbuskula dari Rizosfer Tanaman Berkayu Asal Pulau Bangka dan Karakteristik Struktur Kultur Mikorizanya
Authors: Sukarno Nampiah , Rahmawati Cici , Listiyowati Sri , Fadillah Wendi Nurul , Novera Yanti
Published: July 2023

Arbuscular Mycorrhizal Fungi (AMF) associate with a variety of plants including forest trees. Research on AMF in forestry in Indonesia is limited, especially on woody plants grown in Bangka Island. Therefore, the aim of this research was to isolate and identify AMF associated with woody plants from Bangka Island grown in the post-mining soil in greenhouse for 7 years. The Soil samples derived from 8 pots of the 7 years old woody plants were used as spore sources. Spore extraction from the soil used the wet sieving and decanting method. Fungal identification was carried out based on morphological characteristics, and fungal isolation used pot culture with Pueraria javanica as a host plant. Fungal structures within the root were analyzed after root staining with trypan blue. There were 18 spore morphotypes observed which belong to 5 types of Acaulospora and 13 types of Glomus. Seven single spore pot cultures were successfully isolated from species of Acaulospora sp.1, Acaulospora sp.4, Acaulospora sp.5, Glomus sp.2, Glomus sp.3, Glomus sp.6, and Glomus sp.11. AM fungal colonization structures observed within the root were Paris type arbuscules, internal hyphae, and vesicles. The AMF cultures obtained could be used as biofertilizer for woody plant seedlings production for post mining reclamation activities.
The Effectiveness of Using Webtoon Applications in Teaching Reading Comprehension at The Eighth Grade of SMP Negeri 11 Mataram
Authors: Ghulam Muhammad Thahirul , Nurtaat H. Lalu , Lail Husnul , Sujana I Made
Published: July 2023

Reading is an essential skill in the English language as it significantly impacts learning and facilitates the exploration of information. It enables us to acquire new knowledge, and broaden our perspectives, Grabe & Stoller (2013) contend that reading is a complex and dynamic process that involves considering, understanding, translating, analyzing, and discovering knowledge. Students often encounter multiple challenges when learning reading comprehension, such as limited vocabulary, inadequate time to comprehend the material, and disinterest in the teaching methods employed by educators, so this study aimed to investigate whether the use of a webtoon application as a medium has a significant effect on the achievement scores of second-grade students in literal reading comprehension. The research method used in this study is quantitative, and the researcher conducted a quasi-experimental study to investigate the impact of using Webtoon media in the teaching process. The treatment provided to the experimental group, which received instruction with the use of Webtoon media, while the control group did not receive any special treatment. The results of the study indicated that there was a noticeable difference in the pre-test and post-test scores, with an increase in the mean score from 60.46 to 73.86. Therefore, it was found that webtoon application is effective in teaching reading to improve reading skills, especially students' reading comprehension. The significant effect implies that when the material was presented through the Webtoon application, students became more engrossed in the content, leading to better comprehension of the text.
An analysis of risk factors for ENT diseases: A case study of D. G. Khan and Rajanpur Districts, Punjab, Pakistan.
Authors: Mujahid Hussain  , Muhammad Ejaz  , Aamna Khan
Published: July 2023

Objective: To determine the core risk factors of Ear, Nose and Throat (ENT) diseases at D. G. Khan and Rajanpur districts of Punjab, Pakistan. Study Design: Cross Sectional Case Control study. Setting: A sample of 1553 individuals including two categories, ENT Diseased (Case) and ENT diseased free (Control) respondents including both males and females was collected from different hospitals of D. G Khan and Rajanpur Districts. Period: June 2021 to June 2022. Material & Methods: Data for this study have been collected by formulating a questionnaire. That questionnaire was then completed by face to face interviewing. Chi-squared test is used to check the association between the assumed risk factors and ENT diseases. Odds ratios are calculated to measure the strength of association between assumed risk factors and ENT diseases. Looking at the dichotomous nature of the response variable, a binary logistic regression model is also applied to assess the overall influence of potential risk factors on developing the ENT diseases. Results: In our sample of 1553 respondents, 41.47% are females and 58.53% are males. The percentage of clinically diagnosed ENT diseased patients is 54.92% and those of controlled ones is 45.08%. Among the diseased respondents, 57% have ear disease, 19.2% have nose disease and 23.8% have throat disease. Age, education, family status, family system, marital status, slow physical activity, smoking, Naswar, Paan, family history, occupation, work place, water, ventilation, nutrition and tea are found to be the most significant risk factors of developing the ENT diseases. Conclusions: The occurrence of ENT diseases can be reduced by giving the awareness to the people about its risk factors.
Topical Calcium channel blockers for effective post operative analgesia for hemorrhoidectomy patients; A Randomized Control Trial at a Tertiary Care Hospital.
Authors: Rubina Shahzad  , Sehrish Siddique  , Haniyah Anwar  , Jahangir Sarwar Khan
Published: July 2023

Objective: To compare the mean pain scores after hemorrhoidectomy in patients given topical calcium channel blocker and patients being given routine post-operative treatment only. Study Design: Randomized Controlled Trial. Setting: Surgical Department of Holy Family Hospital. Period: 7th January 2022 to 7th July 2022. Material & Methods: Patients fulfilling the inclusion criteria were divided into two groups. Group A patients will receive topical calcium channel blockers whole group B will receive conventional analgesic medications. Patients in both groups underwent open hemorrhoidectomy under saddle block anesthesia. At the end of procedure, a lignocaine gel-soaked pack was placed in rectum which was removed after 6 hours. The post-operative treatment of test group was similar in all regards except that they were given 2% diltiazem ointment to apply to perianal region twice a day. Oral stool softeners were started after NPO duration. The patients were advised to start warm sitz bath and application of 2% lignocaine gel to perianal region 12 hourly after removal of pack. The patients in both groups were compared for the degree of pain on the second post-operative day using visual analogue scale. Results: In this study, on comparison of mean pain scores after hemorrhoidectomy in patients given topical calcium channel blocker and patients being given routine post-operative treatment only shows that pain in Group-A was 5.89+0.80 and in Group-B 3.60+0.77, p value was 0.0001. Conclusion: Topical Calcium Channel Blockers are effective in managing post hemorrhoidectomy pain.
Serum Vitamin D levels of children attending pediatric clinic at HMC IBP.
Authors: Ambreen Ahmad  , Islam Gul Afridi
Published: July 2023

Objective: To assess the serum vitamin D levels of children attending pediatric clinic at HMC –IBP. Study Design: Prospective Cross Sectional study. Setting: This study was carried out in institution based private clinic of padiatrics in Hayatabad Medical Complex Peshawar. Period: April 2018 to April 2022. Material & Methods: All patients who presented to pediatric clinic with nonspecific bone and muscle pains (especially night time leg pains), mild motor delays and repeated chest infections were included in the study. Patients having clinical signs of rickets were excluded from the study. 5ml venous sample was obtained from each patient after informed verbal consent from parents. Blood test was performed in the hospital laboratory on COBAS E601 instrument employing chemiluminescent Electro Immune assay (ECLIA). Results of vitamin D levels of these patients were recorded on excel sheet and statistically analyzed using SPSS version 25. The variables were put in tables and graph and statistical relationship was assessed for quantitative variables. Definition of Vitamin D Deficiency: No international consensus on the definition of vitamin D deficiency in children exists yet. The Espaghan committee of nutrition and American Academy of pediatrics has not defined the exact definition of vitamin D deficiency. Our hospital used the level as severe to moderate deficiency <10ng/ml. mild/borderline 10-30ng/ml, 30-40ng/ml as hypovitaminosis and 40-100ng/ml as optimum level. Results: This study was conducted on 146 patients. Out of these 146 patients 78 (53.4%) were male and 68(46.6%) were females. The age range was from 1year to 15 years. The combined prevalence of deficiency and insufficiency was 52% and optimum levels were documented in 47.9% children. Severe deficiency according to definition <10ng/ml was documented in10 children (6.8%). Vitamin D levels were reported slightly lower in girls 25.88% as compared to boys 25% but severe deficiency was significantly lower in girls 4.7% as compared to boys 2.3%. p value <.o5 Older children (7-15 years) showed higher levels of vitamin D deficiency 53.4% as compared to infants (1-2 years) of 4.8%. Vitamin D deficiency was reported more in winter months (October-March) 51% than in summer (April –September47%. Conclusion: The study concluded that more than half of the patients who visited pediatric clinic with nonspecific bone and muscle pains were vitamin D deficient.
Frequency of hyperventilation syndrome in asthma.
Authors: Muhammad Waseem  , Muntazir Mehdi  , Maryam Rafiq  , Nauman Aziz  , Hafiza Swaiba Afzal  , Muhammad Junaid Iqbal
Published: July 2023

Objective: Hyperventilation syndrome is not only an important mimicker of asthma but it also increases perception of symptom severity in otherwise known stable asthmatic cases which may lead to increased use of asthma medication and hospital visits. Hyperventilation syndrome recognition is directly related to improvement of quality of life of an asthmatic patient. Study Design: Descriptive Cross-sectional study. Setting: Department of Pulmonology, Sahiwal Medical College Sahiwal. Period: 1st Nov 2019 to 1st May 2020.  Material & Methods: In 400 confirmed asthma patients diagnosis of hyperventilation syndrome was made through the use of Nijmegen score. Data was analyzed and Nijmegen scores were checked in terms of age, gender, co-morbid state. Association of Nijmegen score with number of hospital visits and frequency of use of rescue medication was also checked. Results: Younger females having asthma have the highest frequency of hyperventilation syndrome. Asthmatics with obesity and hypertension as co-morbid conditions are more prone to develop hyperventilation syndrome. Increased Nijmegen scores hence increased severity of hyperventilation syndrome is associated with poor control of asthma, increased use of reliever medicine and more frequent emergency department visits. Conclusion: Hyperventilation syndrome is a common cause of deteriorating quality of life of asthmatics however it is ignored most of the time in management of asthma. Every asthmatic with obesity, difficult to control asthma and frequent emergency visits should be looked for underlying hyperventilation syndrome and must be treated accordingly. There should be more research work on causes, diagnosis and management of hyperventilation syndrome.
Microhistoria de una resistencia: el caso de la exoneración de Malva Hernández del Pedagógico de la Universidad de Chile, 1978-1980
Authors: Cisterna Bahamondes Juan Ignacio , Aravena Soto Luis Esteban
Published: July 2023

Este artículo aborda las expresiones de resistencia estudiantil contra la dictadura cívico-militar en el Pedagógico de la Universidad de Chile entre 1978 y 1980. A modo de hipótesis, sostenemos que la exoneración de la profesora Malva Hernández, en 1980, cristaliza la primera etapa de la resistencia en el micro mundo del Pedagógico, mostrando la censura, vigilancia y represión de la dictadura, así como también las motivaciones de la movilización estudiantil. A juicio de los autores, este caso constituye una experiencia particular de resistencia prematura para el contexto nacional, tensionando así la visión tradicional sobre la articulación de la movilización estudiantil en dictadura. En su aspecto teórico metodológico, este trabajo propone un diálogo entre la microhistoria y la memoria, mediante el análisis de testimonios, prensa y archivos sumarios, sugiriendo el contacto entre ambas corrientes historiográficas y su potencialidad para abordar casos de terrorismo de Estado, así como las expresiones de resistencia.
La renovación urbanística de Santiago de Chile, 1930-1941: la visión de la prensa en la víspera de su cuarto centenario
Authors: Guerrero Gutiérrez Antonio
Published: July 2023

El 12 de febrero de 1941 se conmemoraron 400 años de la fundación de Santiago de Chile, hito relevante en la historia de la ciudad y de sus habitantes. Ya una década antes de dicha celebración tanto autoridades como diversos actores sociales de la época comenzaron a prepararse para ese momento. Testigo privilegiado de ello fue la prensa, desde la cual emergió un proceso reflexivo sobre lo que representaba esta conmemoración para la conciencia e identidad de sus habitantes. El objetivo de este artículo es caracterizar cómo la prensa capitalina, desde su tribuna, contempló y valoró a la ciudad ad-portas de este hito referencial. El foco principal de análisis está puesto en uno de los aspectos más destacados del periodo, como fue la renovación urbanística de su radio urbano y su transformación en símbolo de la anhelada modernidad para Santiago. Este proceso, que tuvo en la noción de “progreso” uno de sus pilares fundamentales, no estuvo exento de críticas a través de la constatación de importantes contradicciones.
PERBANDINGAN MODEL REGRESI WEIBULL DAN REGRESI COX PROPOSIONAL HAZARD
Authors: Mayawi Mayawi , Nurhayati Nurhayati , Laamena Novita Serly , Bustan Ariestha Widyastuty , Salmin Munazat , Talib Taufan
Published: July 2023

This study aims to determine the model of Acute Myocardial Infarction using the Weibull Regression and Cox Proportional Hazard Regression methods to determine the factors that significantly influence the length of time for recovery of acute myocardial infarction patients. The results of this study indicate that the factors that significantly influence the recovery time of acute myocardial infarction patients are age, onset, number of secondary diagnoses and duration of pain. Based on the AIC value, the Weibull regression model is the best regression model because the AIC value is smaller, namely 292.883 compared to the Cox Proportional Hazard regression model with an AIC value of 493.3971
KEMAMPUAN PEMECAHAN MASALAH DAN SELF EFFICACY MAHASISWA DALAM MENYELESAIKAN WORKSHEET PERSAMAAN DIFERENSIAL TINGKAT SATU DERAJAT N
Authors: Rofiroh Rofiroh , Mahuda Isnaini , Talib Taufan , Faqihuddin Faqihuddin
Published: July 2023

This study aims to describe the problem solving ability of UMT students in solving the first degree differential equations worksheet with the factorization method. This research is included in the category of qualitative research with a descriptive category. The research subjects were 20 fourth semester students for the 2021/2022 academic year. Data collection methods used are test techniques, filling out structured student worksheets and filling out questionnaires. The test is carried out by filling out the initial test. Filling out structured student worksheets consisting of material, examples and practice questions. Based on the initial test data, filling in the worksheets and questionnaires, the criteria for the three types of students were obtained. Type 1 students fill out 1-2 initial test questions, fill in the material incompletely, the sample questions are only done one question out of the two questions provided with unsystematic problem solving analysis and the last part of the practice questions is not filled in. Type 2 students fill out 2-3 questions for the initial test, complete the material, two examples of questions are done, the practice questions are filled with one question. Type 3 students work on 4 pre-test questions, complete structured student worksheets for each material, sample questions and practice questions. The student fills out a worksheet with a systematic problem-solving analysis
MODEL EVALUASI FORMATIF-SUMATIF TERHADAP HASIL BELAJAR MATEMATIKA MELALUI PEMBELAJARAN BERDIFERENSIASI PADA PESERTA DIDIK SMA
Authors: Gaspersz Magy , AW Suranto , Gaspersz Netty
Published: July 2023

Evaluation is a means to improve the quality of education through the results of information that is used as feedback and improvements to educational programs, one of which is the formative-summative evaluation model. This study aims to determine the effect of the formative-summative evaluation model on mathematics learning outcomes through differentiation learning in high school students. This type of research is evaluation research with a quantitative approach. Data were obtained through documentation techniques by taking samples based on certain considerations (purposive sampling), namely classes that have implemented an independent learning curriculum and educators who teach are driving educators so that planning in differentiated learning can run as expected. The results of the analysis using multiple linear regression tests obtained that there was a significant influence between the formative-summative evaluation model on mathematics learning outcomes as shown from the calculations obtained by the value of Fcount = 89.8 with a significant level of 0.05, then Ftable = 3.316 so that Fcount > Ftable or 89.8 > 3.316 then H0 is rejected. This shows that the formative-summative model can be used to evaluate student’s mathematics learning outcomes through differentiation learning
PENGEMBANGAN MEDIA FLIPBOOK BERBASIS REALISTIC MATHEMATICS EDUCATION PADA KEMAMPUAN KOMUNIKASI MATEMATIS PESERTA DIDIK
Authors: Karsim Karsim , Ratnaningsih Nani , Rahayu Diar Veni
Published: July 2023

Teacher’s lack of interactive learning media and abstract mathematics learning materials results in low mathematical communication skills as indicated by students' answers in solving math problems. Flipbook media is one of the interactive and interesting learning media in learning mathematics which accommodates the principles of the Realistic Mathematics Education (RME) approach. This study aims to determine the procedure for developing RME-based flipbook media and to determine students' mathematical communication skills after using the media developed on circle material. This type of research is R & D (Research & Development) research using the 4D development model (Define-Design-Develop-Disseminate). The subjects in this study were 3 mathematics teachers, 6 students taken from each class VIII outside class VIII-E, 2 material experts, 2 media experts and 32 students from class VIII-E SMPN 3 Banjar. Data collection techniques are observation, interviews, questionnaires and tests. The data analysis technique used is descriptive statistical analysis and qualitative data analysis. Based on the analysis of the results of the mathematical communication ability test, as many as 31.25% of students showed a level of mathematical communication ability in the "high" category, as many as 43.75% of students showed a level of mathematical communication ability in the "medium" category as many as 25% of students shows the level of mathematical communication skills in the "low" category. It can be concluded that RME-based flipbook learning media is feasible and effective in students' mathematical communication skills. This research is a reference for teachers to make flipbooks using Flip PDF Professional software which can assist the learning process and further researchers can conduct research and development of flipbooks in collaboration with other software on different material and mathematical abilities
PENINGKATAN HASIL BELAJAR SISWA PADA MATERI RELASI DAN FUNGSI DI KELAS VIII SMP NEGERI 15 AMBON DENGAN MENGGUNAKAN MODEL PEMBELAJARAN GUIDED DISCOVERY LEARNING
Authors: Addawiyah Robiatul , Mataheru Wilmintjie , Tamalene Hanisa
Published: July 2023

Penelitian ini bertujuan untuk mengetahui peningkatan hasil belajar siswa dalam mempelajari materi relasi dan fungsi di kelas VIII dengan menggunakan model pembelajaran guided discovery learning. Subjek dalam penelitian ini adalah siswa kelas VIII-2 SMP Negeri 15 Ambon yang berjumlah 29 siswa. Penelitian ini merupakan penelitian tindakan kelas dan berlangsung dalam 2 siklus. Pengumpulan data dilakukan dengan menggunakan tes dan lembar observasi. Teknik analisis data yang digunakan adalah teknik analisis data kualitatif dan teknik analisis data kuantitatif. Hasil analisis menunjukkan bahwa terjadi peningkatan hasil belajar di setiap siklus  dengan presentase ketuntasan siklus I 41,67% dan presentase ketuntasan siklus II 75%. Hasil belajar siswa naik 33,33% dari siklus I ke siklus II.
PENGARUH MODEL PEMBELAJARAN PBL, DL, EL DAN GAYA BELAJAR TERHADAP HASIL BELAJAR MATEMATIKA
Authors: Deeng Vernel , Domu Ichdar , Tilaar Anetha T. F
Published: July 2023

Penelitian ini bertujuan untuk mengetahui pengaruh interaksi antara model pembelajaran (Problem Based Learning, Discovery Learning, dan Expository Learning) dan gaya belajar (Visual, Auditorian dan Kinestetik) . subjek penelitian ini adalah kelas VII A, VII B, dan VII C SMP Advent 04 Paal Dua Manado tahun ajaran 2020/2021. Gaya belajar siswa ditentukan menggunakan angket dan hasil belajar siswa menggunakan instrument tes materi aritmatika social. Setiap kelas diberikan perlakuan dengan menggunakan model pembelajaran PBL, Discovery learning, dan expository learning. Analisis data menggunakan menggunakan analisis varians dua arah. Hasil penelitian menunjukan bahwa interaksi antara model pembelajaran dan gaya belajar mempengaruhi hasil belajar siswa. Siswa yang memiliki gaya belajar visual memiliki hasil belajar yang maksimal jika diterapkan model pembelajaran PBL, siswa yang memiliki gaya belajar Auditorial memiliki hasil belajar yang maksimal jika diterapkan model pembelajaran Ekspository learning, dan siswa yang memiliki gaya belajar Kinestetik memiliki hasil belajar yang maksimal jika di terapkan model pembelajaran PBL, sehingga  Penerapan model pembelajaran yang disesuaikan dengan gaya belajar yang tepat bisa memaksimalkan hasil belajar siswa.
The Solving Indonesian Intellectual Property Rights Transfer Issue
Authors: Situmeang Ampuan , Silviani Ninne Zahara , Tan David
Published: July 2023

The aim of this research was to analyze legal problems that are hindering the process of intellectual property rights (IPR) transfer within the Indonesian legal system. This objective was achieved by employing the normative legal research method with a statutory approach while, utilizing secondary data. Accordingly, the secondary data used consisted of primary legal sources, including Law No. 30 of 2000 on Trade Secrets, Law No. 20 of 2016 on Trademarks and Geographical Indications, Law No. 28 of 2014 on Copyrights, Law No. 13 of 2016 on Patents, as well as relevant judicial decisions made within the Indonesian legal system, which enhanced the analysis. This research showed the problems that exist within the Indonesian legal system regarding the transfer of IPR and identified the contributing factors. Furthermore, from the analysis conducted, it was found that the Indonesian IPR legal framework is too complex and lacks harmony, specifically when it comes to the mechanisms involved in IPR transfer and the bureaucratic efficiency associated with these processes. This research serves the purpose of providing comprehensive literature for the development of better intellectual property laws, which are continuously being refined by the Indonesian government to protect and foster creativity in the economy of the country, thereby making it a more attractive prospect for capital. Unlike previous studies, this research placed significant emphasis on legal problems specifically hindering the process of IPR transfer and examined their impacts on actual IPR cases within the Indonesian legal system.
Sharia Banking Disputes Settlement: Analysis of Religious Court Decisions in Indonesia
Authors: Hidayah Nur , Azis Abdul , Mutiara Tira , Larasati Diah
Published: July 2023

This study aims to analyze Sharia banking dispute settlements in Religious Courts regarding Sharia compliance and state regulations. The data is collected from the Supreme Court of the Republic of Indonesia website on Profit Sharing (PLS) financing, musyarakah, and non-profit Sharing (non-PLS) financing, murabahah. It is legal empirical research with a comparative approach. The results of this study indicate that Sharia banking disputes occur partly because there are still legal loopholes due to the general nature of the existing rules leading to multiple interpretations. The disputes are contributed mainly by default and unlawful acts. There are differences in the judge's decisions in the two case studies related to the fulfillment of legal principles in the form of benefits, justice, and legal certainty in the decisions made. Regarding the suitability of the contract, in the murabahah case, the pillars and conditions have been fulfilled, but there are other things that damage the contract. There has been an urgent need to strengthen regulations related to more detailed financing contracts. The regulators should promote an Islamic banking regulatory framework that guarantees legal certainty for both parties, the customers and Islamic financial institutions, as well as provide a stronger legal basis for dispute settlements.
The Ambiguity of Using the Statement of Absolute Responsibility Based on Minister of Home Affairs Regulation Number 109 of 2019: Study in Dharmasraya Regency, West Sumatra Province, Indonesia
Authors: Nofialdi Nofialdi , Elimartati Elimartati , Iska Syukri , Rizal Deri , Firdaus Firdaus , Kasmidin Kasmidin , Hamdani Hamdani
Published: July 2023

Marriages are required to be registered under the provisions of Law Number 1 of 1974, specifically Article 2. This registration plays a crucial role in establishing the legality of marriages and enables the utilization of different associated benefits. Meanwhile, unregistered marriages give rise to a range of legal issues, including uncertainties regarding lineage, concerns related to maintenance, and inheritance rights. In line with the Ministry of Home Affairs Regulation Number 109 of 2019 regarding Population Administration, couples involved have the option to obtain important documents such as the Population Identification Card (KTP), Birth Certificate, and Family Card (KK) by signing a Statement of Absolute Responsibility (SPTJM). This situation raises significant concerns regarding the legal implications of unregistered marriages. Therefore, this study aimed to employ an empirical legal approach with qualitative methods and obtained data through interviews, observations, and documentation. The data analysis used Miles and Huberman's method to uncover the meaning within Ministry of Home Affairs Regulation Number 109 of 2019 regarding Unregistered Marriages and unveiled the ambiguity in understanding the true meaning. Furthermore, a study conducted in Dharmasraya Regency in 2021 discovered the issuance of 69,144 Family Cards by the Directorate General of Population and Civil Registration, and 22,453 (32.47%) were unregistered marriages. Only 194 individuals applied for validation (isbat) within 3 years, where 101, 27, and 66 were accepted, rejected, and revoked, respectively. In conclusion, the community perceived their marriages to be legal due to the issuance of Ministry of Home Affairs Regulation Number 109 of 2019, even though the SPTJM did not legalize the concept or hold legal authority over the consequences.
Freedom of Speech Without a Direction: Criticism of Promotion of Freedom of Speech in Indonesia
Authors: Sayuti Sayuti , Yanti Illy
Published: July 2023

Attempts to equate freedom of speech with other rights, such as freedom of expression or freedom of opinion, are wrong. Because these rights already have their respective territories, both in efforts to promote them and in terms of settling legal violations. However, in practice in Indonesia, this error still occurs, the indications are that there is still no law that specifically regulates freedom of speech. On that basis, this article wants to look at the factors that lead to a legal vacuum for freedom of speech, and solutions to overcome this vacuum. This article uses a normative juridical approach to inventory various legal products and practices for making decisions or policies regarding the promotion of freedom of speech after the 1998 Reform Era in Indonesia. In the end, this article finds that the legal vacuum in efforts to promote the right to freedom of speech is caused still there the tug-of-war between the importance of promoting human rights, and the ambiguity of the understanding of freedom of expression. Therefore, it is important to synchronize laws and regulations regarding the rights belonging to freedom of expression, and strengthen regulations on freedom of speech that specifically contain definitions, limitations, and ways of resolving violations of the law. Specifically strengthening regulations, is formed in the form of statutory regulations which are under the constitution, so that there is a detailed legal direction or umbrella for efforts to promote freedom of speech.
PENGARUH AROMATERAPI JAHE (Zingiber officinale) TERHADAP MUAL MUNTAH PASIEN KANKER PASCA KEMOTERAPI
Authors: Tobing Yauwan Tobing Lukiyono , Nidianti Ersalina , Zain Salfa Salsabilah
Published: July 2023

Kemoterapi adalah prosedur medis yang digunakan untuk menghentikan pertumbuhan sel kanker. Kemoterapi melibatkan menyuntikkan atau menelan bahan kimia. Obat kemoterapi sitotoksik dapat menyebabkan efek samping yang tidak menyenangkan seperti mual dan muntah. Terapi nonfarmakologi seperti terapi kombinasi dengan aromaterapi jahe dan relaksasi otot progresif dapat digunakan untuk mengatasi mual dan muntah. Dengan menurunkan atau menghentikan mual dan muntah, aromaterapi jahe bisa menenangkan. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian aromaterapi jahe terhadap mual muntah pada pasien kanker pasca kemoterapi. Penelitian ini menggunakan metode literatur dengan mencari berbagai sumber dari peneliti-peneliti sebelumnya yang kemudian dijadikan bahan acuan untuk membuat artikel ini. Hasil yang didapatkan yaitu efek dari aromaterapi jahe adalah menghambat reseptor serotonin agar serotonin tidak berhasil di produksi dan tidak terjadi kontraksi pada otot-otot pada perut sehingga mampu mengurangi kondisi mual dan muntah. Kesimpulan yang didapatkan yaitu aromaterapi jahe sudah terbukti dapat memberikan efek menenangkan dan membuat seseorang relaksasi. Kandungan senyawa yang ada didalam jahe seperti zingiber dan zingiberol memiliki efek anti emetik yang dapat mengurangi terjadinya mual dan muntah.