bluuebunny/crossref_metadata_2025 huggingface dataset:
Revisión bibliométrica de COVID-19 en el periodo diciembre 2019 y julio 2020
Authors: Pino-Villarreal Luis Eduardo , Triana Avellaneda Iván Camilo , Barros-Barraza Mateo , Viola-Muñoz Lucía Carolina
Published: August 2020

Objetivo: Conocer las características de la información publicada acerca de Covid-19 y el potencial impacto generado por la enfermedad.

Métodos: Revisión bibliométrica del total de la literatura y de Covid-19 en Pubmed, Scopus y Lilacs publicada entre diciembre de 2019 y marzo de 2020. Se clasificaron los artículos por categorías (objetivo, país, especialidad) y se comparó con la literatura del año anterior.

Resultados: Se encontraron 1510, 655 y 30 publicaciones acerca de Covid-19 en Pubmed, Scopus y Lilacs respectivamente. La principal especialidad médica por búsqueda fue infectologia. De acuerdo al objetivo, el más encontrado fue epidemiología (35,7%). El país con más publicaciones de Covid-19 fue Estados Unidos (31,8%) en Pubmed. En el lapso Covid-19 las publicaciones de la enfermedad representan 0.005% del total.

Conclusiones: Existe un crecimiento inusitado de publicaciones de Covid-19 en 2020 y de publicaciones totales en comparación a estadísticas de hace un año, lo cual es significativo para una sola enfermedad.
Ataque al personal de la salud durante la pandemia de Covid-19 en Latinoamérica
Authors: Abuabara Yazmín Cecilia
Published: August 2020

El FIMI son:

Pascual Rubén Valdés, Luis Alberto Cámera, Mariano De La Serna • (Argentina) / Yazmín Abuabara-Turbay, Virgil Carballo-Zárate, Helí Hernández-Ayazo, Rita Magola Sierra-Merlano, Aníbal Viera-Jaraba • (Colombia) / Diana Rodríguez-Hurtado • (Perú) / Andrea Vaucher-Rivero • (Uruguay) / Felipe Melgar-Cuéllar, Carlos Ibáñez-Guzmán, • (Bolivia) / Carlos Araya-Fonseca (Costa Rica) • Isis Betancourt-Torres • (Cuba) / Rubén Montúfar-Guardado • (El Salvador) / Carlos Nitsch-Montiel • (Guatemala) • Claudia Regina Brav-Mejía, Denisealejandra Salgado-Guevara, Pamela Lizzeth Bustillo-Valeriano • (Honduras) /Alejandro Cárdenas-Cejudo, Mauricio Sarmiento-Chavero • (México) / Nuvia Batista-Rujano • (Panamá) / María Cristina Jiménez • (Paraguay) / Claudia Y. Arias-Burroughs (República Dominicana) / Maritza Durán-Castillo (Venezuela) / Santiago Carrasco-Dueñas (Ecuador)

 

En la actualidad los profesionales de la salud son el recurso más valioso con el que cuenta cada país para combatir la enfermedad COVID-19. Las tasas de contagio intrahospitalario son altas y ligadas al acto de atención sanitaria. Las medidas de protección por parte de los empleadores son fundamentales para el cuidado de los que cuidan. La situación de pánico generada por el temor a contraer o transmitir la enfermedad, siendo primeros respondedores en la línea de combate ante la pandemia, ha sido amplificada por varios factores. Cuestiones como presión psicológica, carga laboral, mediatización, aspectos judiciales, desprotección, falta de descanso, nuevos roles, discriminación y agresiones son algunas de las situaciones a las que se los profesionales se deben enfrentar
Perlindungan Hukum dalam Malpraktik untuk Pelayanan Kesehatan Gigi
Authors: Sutrisno Endang , Hartini Inge , Erika Erika
Published: August 2020

Malpraktikkdapat diartikan sebagai sebuah kelalaian atau kegagalan seorang dokter untuk mempergunakanntingkat keterampilan dan ilmu pengetahuannya yang lazim dipergunakanndalam mengobati pasien. Tindakan medis ortodonti harus dikerjakan dengan sangat hati-hati sehingga oleh tenaga medis sesuai dengan kompetensi dan kewenangannya. Berbagai kemungkinanndapattterjadi jika perawatannortodontik cekat dilakukan olehhseseorang dengannkompetensi yang tidak sesuai termasuk dokter gigi. Temuan penelitian secara umum dokter gigi sudah mengetahui aturan batasan kewenangan dalam melakukan perawatan gigi terutama dibidang ortodonti cekat, namun tetap ada yang melanggar aturan tersebut. Denganntanpa adanya kompetensi dan kewenangan yang dimiliki dokter gigi serta tidak dilakukan rujukan kepadaadokter gigi spesialis ortodonti yang lebih berkompetensi makaadokter gigi tersebut dapat dikenakan sanksi disiplin dan pertanggungjawabannsecaraapidana berdasarkannpasal 69 ayat (3) Undang- Undang Nomor 24 Tahunn2004 tentang Praktik Kedokteran. Dibutuhkan pengawasan dan pembinaan oleh para pemangku kepentingan, tetpai hal tersebut tidak berjalan optimal
Pemanfaatan Lapangan Rumput Sebagai Sarana Pembelajaran Siswa Kelas VII Melalui Metode Discovery Learning Pada Materi Klasifikasi Makhluk Hidup Di SMP Yabujah Segeran Indramayu
Authors: Fatah Miftahul
Published: August 2020

Penelitian ini dilatarbelakangi oleh sebuah fenomena bahwa penggunaan dan pemanfaatan media pembelajaran dapat mempengaruhi prestasi belajar IPA biologi, dalam hal ini peneliti memanfaatkan lapangan rumput menggunakan media pembelajaran discovery learningpada materi klasifikasi makhluk hidup di SMP Yabujah Segeran Indramayu. Berdasarkan nilai rata-rata di setiap akhir siklus kegiatan pembelajaran yang menggunakan model pembelajaran discovery learning, menunjukkan terjadi peningkatan hasil belajar ranah kognitif IPA siswa kelas VII SMP Yabujah Segeran Indramayu. Peningkatan nilai rata-rata kelas sebesar 5,56, dari 76,38 pada siklus I menjadi 81,84 pada siklus II. Persentase jumlah siswa yang mencapai nilai KKM atau dinyatakan tuntas belajar juga terjadi peningkatan sebesar 23,28%, dari 61,53% pada siklus I menjadi 84,81% pada siklus II. Pada siklus I terdapat 7 siswa yang belum mencapai KKM, sedangkan pada siklus II tinggal 2 siswa yang belum mencapai KKM. Dapat dikatakan bahwa pada siklus II ada kenaikan 5 siswa yang telah mencapai KKM. Peningkatan hasil belajar IPA terjadi sangat signifikan pada siklus II karena peneliti telah menerapkan 7 komponen model pembelajaran discovery learningdalam pembelajaran IPA secara tepat. Komponen utama model pembelajaran discovery learningyaitu konstruktivisme, bertanya, menemukan/inkuiri, masyarakat belajar, pemodelan, refleksi, dan penilaian autentik.
Parkour: propostas de aulas na educação física escolar
Authors: Sena Dianne Cristina Souza de , Lemos Miguel Herick Sousa de
Published: August 2020

INTRODUÇÃO: O Parkour é uma manifestação da cultura corporal de movimento que foi incluído na Base Nacional Curricular Comum (BNCC), por meio da unidade temática Práticas Corporais de Aventura. Sabe-se que alguns professores de Educação Física limitam suas aulas por não terem informações corretas sobre conteúdos não tradicionais e pela falta de estudos científicos relacionados ao parkour no âmbito escolar. OBJETIVO: O estudo tem como objetivo apresentar propostas de aulas do parkour na educação física escolar. MÉTODOS: A pesquisa é do tipo qualitativa e descritiva, com público-alvo de 30 estudantes do 9º ano do ensino fundamental anos finais. A técnica de investigação foi a observação, realizada a partir dos planos de aulas e imagens das atividades. RESULTADOS: Diante dos planos de aulas ministrados, observamos a participação, o entusiasmo e o empenho dos estudantes na aprendizagem dos movimentos e habilidades motoras básicas do parkour. CONCLUSÃO: O desenvolvimento das aulas foi significativo para os estudantes no que se refere a promover diversas perspectivas de aprendizagens (motoras, cognitivas, afetivas, cultural, social e emocional) do parkour. Promovemos atividades de forma sistematizadas, adequada com a faixa etária e pertinente com a realidade dos estudantes. Objetivamos o aprendizado de forma lúdica, com criatividade usando poucos materiais e espaço não delineado. O estudo é relevante já que há poucos estudos científicos sobre a prática do parkour no contexto escolar. ABSTRACT. Parkour: class proposals in school physical education. BACKGROUND: Parkour is a manifestation of the body culture of movement that was included in the National Common Curricular Base (BNCC), through the thematic unit body adventure practices. It is known that some Physical Education teachers limit their classes because they do not have correct information about non-traditional content and because of the lack of scientific studies related to parkour in the school environment. OBJECTIVE: The study aims to present proposals for parkour classes in school physical education. METHODS: This is a qualitative and descriptive research with a target population of 30 students in the ninth grade of elementary school. The study utilized observation methodology through lesson plans and images of activities. RESULTS: We observed the participation, enthusiasm, and commitment of students in learning the basic movements and motor skills of parkour. CONCLUSION: The development of classes was significant for students in terms of promoting diverse learning perspectives (motor, cognitive, affective, cultural, social, and emotional) of parkour. We promoted activities in a systematic way, which were appropriate to the age group and relevant to the students’ reality. Our goal is to promote fun learning through creativity using few materials and nondelineated space. The study is relevant because there are few scientific studies on the practice of parkour in the school context.
Avaliação da performance técnico-tática no tênis: uma revisão sistemática sobre os instrumentos de medida
Authors: Bulso Rodrigo Vieira , Gonçalves Gabriel Henrique Treter , Leonardi Thiago José , Balbinotti Carlos Adelar Abaide
Published: August 2020

OBJETIVO: O estudo teve como objetivo revisar a literatura a fim de identificar instrumentos de avaliação da performance técnico-tática no tênis. MÉTODOS: Foi realizado um estudo de revisão sistemática. A busca por artigos foi realizada nas bases de dados SCOPUS e WEB OF SCIENCE, utilizando-se os termos tennis AND performance AND assessment. Os critérios de inclusão estabelecidos para este estudo foram: (1) artigos de validação de instrumentos; (2) que tratassem de pelo menos um aspecto técnico ou tático; (3) que fossem específicos do tênis. Dos 422 artigos encontrados, sete foram selecionados para esta revisão.RESULTADOS: Os instrumentos selecionados avaliavam em sua maioria os aspectos técnico-táticos do tênis de forma integrada, contemplando desde o público infantil até o público adulto de alto rendimento. Foi observado um maior número de instrumentos de avaliação no contexto do treino em relação ao contexto da competição. Todos os estudos apresentaram ao menos uma evidência de validade, e apenas dois estudos não apresentaram evidências de confiabilidade.CONCLUSÃO: Esta revisão pode auxiliar treinadores e pesquisadores da área a escolher o instrumento de avaliação mais adequado de acordo com o contexto e os objetivos almejados.ABSTRACT. Technical-tactical performance assessment in tennis: a systematic review of measurement instruments.OBJECTIVE: The study aimed to review the literature to identify instruments for assessing technical-tactical performance in tennis.METHODS: A systematic review study was carried out. The search for articles was carried out in the SCOPUS and WEB OF SCIENCE databases, using the terms tennis AND performance AND assessment. The inclusion criteria established for this study were: (1) instrument validation articles; (2) dealing with at least one technical or tactical aspect; (3) that were specific to tennis. From a range of 422 articles found, we selected seven for this review. RESULTS: The selected instruments evaluated mostly the technical-tactical aspects of tennis in an integrated way, covering from the child community to the high performance adult community. We observed a greater number of assessment instruments applied to the context of training in relation to the competition context. All studies presented at least one evidence of validity, and only two studies did not show evidence of reliability.CONCLUSION: This review can help coaches and researchers to choose the most appropriate assessment tool according to the context and to their targeted goals.
Penerapan Pewarnaan Graf Terhadap Penyusunan Jadwal Seminar Proposal Skripsi di Prodi Pendidikan Matematika UIN Raden Intan Lampung
Authors: Novian Riskiana Dewi
Published: August 2020

Mathematics Education of UIN Raden Intan Lampung has a problem in the process of preparing the thesis proposal seminar schedule, because there are many students who conduct seminars in the adjacent period. During this time the preparation of the proposal seminar schedule is done manually, not infrequently many schedule lecturers and examiners are clashing with other student proposal seminar schedules. To overcome these problems, a thesis proposal seminar schedule was arranged by applying the concept of point coloring to graphs using the Welch Powell Algorithm. The points on the graph are represented as students who will conduct a thesis proposal seminar, while the side that connects the two points states that these two points have one and / or two supervisors. The research method used is the study method of literature study. The results of this study indicate that graph coloring using Welch Powell algorithm can be applied to arrange seminar schedule for students' thesis proposal for Mathematics Education, Faculty of Tarbiyah and Teacher Training. UIN Raden Intan Lampung.
The Boron & De Weer Model of Intracellular pH Regulation
Authors: Occhipinti Rossana , Safaei Soroush , Hunter Peter J. , Boron Walter F.
Published: August 2020

The classic Boron & De Weer (1976) paper provided the first evidence of active regulation of pH} in cells by an energy-dependent acid-base transporter. These authors also developed a quantitative model --- comprising passive fluxes of acid-base equivalents across the cell membrane, intracellular reactions, and an active transport mechanism in the cell membrane (modelled as a proton pump) --- to help interpret their measurements of intracellular pH under perturbations of both extracellular CO2/HCO3- and extracellular NH3/NH4+. This Physiome paper seeks to make that model, and the experimental conditions under which it was developed, available in a reproducible and well-documented form, along with a software implementation that makes the model easy to use and understand. We have also taken the opportunity to update some of the units used in the original paper, and to provide a few parameter values that were missing in the original paper. Finally, we provide an historical background to the Boron & De Weer (1976) proposal for active pH regulation and a commentary on subsequent work that has enriched our understanding of this most basic aspect of cellular physiology.
DOI minting test
Authors: physiome figshare admin
Published: August 2020

Testing the minting of DOIs.
Hydromagnetic Natural Convection Heat Transfer of Copper-Water Nanofluid within a Right-Angled Triangular Cavity
Authors: Tarikul I. , Nazma P. , Md F.A.A.
Published: August 2020

This investigation on free convection flow and temperature transfer within a right-angled triangular cavity loaded uniformly by Cu-H2O nanofluid including heated boundary conditions at horizontal side is performed numerically. The standing side is cooled at low heat while the hypotenuse of the triangular is insulated. The governing non-dimensional highly non-linear partial differential equations are performed by employing Galerkin weighted residual finite element method. The simulated numerical findings are exhibited using streamline contours, isotherm contours and average Nusselt number for the sampling parameters named nanoparticles volume fraction, Rayleigh number, and Hartmann number. The outcome demonstrates temperature transfer value reduces for the enhancement of Hartman number whereas improve significantly for the increase of buoyancy driven parameter Rayleigh number. Also, an excellent average temperature transfer is observed for uniform heated boundary condition (case I) compared to non-uniform thermal boundary conditions (case II & case III).
Common Factors of Motivated Individuals
Authors: McMillen Joshua
Published: August 2020

This is a report that I wrote documenting a study that I conducted while working for my Master’s degree at Anaheim University. I was curious as to what the common factors between my motivated students are. To get a sense of their study habits and interest level in English, I produced a survey for them to answer one day in class. The survey was composed of 10 multiple choice questions and 5 questions where the students indicated on a scale how they feel towards English. Three classes were given this survey to fill out. The outcomes to their surveys are reported and analyzed within this report.
Reflection Through Dialogue: Conducting a Mentoring Session with a Juku Colleague Using the ‘Wheel of Reflection’ Tool
Authors: MacDonald Ewen
Published: August 2020

This reflective article outlines a mentoring session conducted with a former colleague in which I took the role of a mentor. The aim of the session was to support my colleague to reflect on themselves as a teacher through engaging in reflective dialogue. To help facilitate this, an advising tool called the ‘Wheel of Reflection’ was used to help my colleague analyse their level of satisfaction for different aspects of their teaching, identify areas where they would like to improve their satisfaction level, and come up with an actionable plan for how to do this. In the article, I briefly discuss reflective dialogue and the purpose of mentoring. I then outline the flow of the mentoring session and what I did as a mentor to help facilitate the reflective dialogue. Finally, I reflect on the session, the benefits for myself and my colleague, and what I learnt from the process.
Measuring the Effectiveness of Time Management Training in EFL Classes: Phase 1 of a Mixed Methods Study
Authors: Arnott Christopher , Curry Neil , Lyon Phoebe , Mynard Jo
Published: August 2020

In this paper, the authors describe an intervention and research project that aims to understand how students manage their time, and also to investigate the impact of integrating time management training activities into a general English language proficiency course. The results will be shared in subsequent papers, but the rationale, background and methods are presented here in order to document the initial stages of the project. Students in three university English classes in a Japanese university participated in the time management training activities and completed reflection sheets which will later be analysed qualitatively. In addition, participants completed a pre- and post- intervention multiple choice questionnaires about time management. A control group comprising three similar classes also completed the pre- and post- intervention questionnaire, but did not participate in the time management training activities or reflection tasks.
A Case Study of Two Japanese English Learners: Their Motivation and Concept of English
Authors: Yamamoto Azusa
Published: August 2020

Learners’ motivation is one of the crucial factors in the ultimate achievement of language learning. To understand how Japanese English learners’ motivation changes over time, and how their experiences influence their concept of English and English learning, it is beneficial to look closely into personal stories of individual learners. Through interviews of two Japanese female adults, it was found that their perception of English was affected by school English education and their own experiences. In addition, the level of achievement in Japanese school setting did not necessarily determine the ultimate proficiency of English in the long run. Furthermore, there was a strong relationship between their level of motivation and their learning context, and their self-image played an important role in creating and keeping their motivation.
Reflecting on Different Types of Successful Recasts and Uptake for a Motivated Adult Learner
Authors: Gruendel Kyoko
Published: August 2020

Nowadays, more and more people pay more attention to communicating in English in business world as well as in their everyday life. Especially, since the 2020 Olympics will be held in Tokyo, some people may be thinking that they would like to help tourists who come to Japan in any way they can. My adult learners seem to be no exception.
Autonomy and Interdependence in a Self-Directed Learning Course
Authors: Moore Paul J. , Mynard Jo , Wongsarnpigoon Isra , Yamamoto Kie
Published: August 2020

This paper provides the background to an ongoing study which aims to investigate ways in which Japanese learners of foreign languages make use of online and offline resources during a period of self-directed study. The researchers are currently collecting data from interviews, learning journals, and other documentation produced by ten EFL learners as part of a self-directed learning course at a university in Japan. This paper will give insights into the rationale and researchers’ motivations for the study, some background on the course, the learners, and the institution; a brief review of the relevant literature; and details of the research methods. Findings will be presented in subsequent publications.
Study regarding the Establishment of Cross-sectional Parameters of Forming Taps
Authors: Lepadatescu Badea
Published: August 2020

In the paper is presented some consideration regarding the parameters that influence the cross sectionalparameters of forming tap. It is taking into account the parameters that have a great influence on the ridges of theforming taps which determine the contour shape of the forming tap’s ridges, the radius of the ridge profile, anddetermination of the radial chamfer relief of the forming tap.Also are shown the influence of the correlation angle on ridge thread that determine the contact area between thetop of the working ridge and of the part subjected to plastic deformation in order to avoid its cutting.
Karakteristik Ibu Nifas Tentang Perawatan Payudara Di BPM Umi Lestari CW, A.Md.Keb Desa Plesungan Kecamatan Kapas Kabupaten Bojonegoro
Authors: Rahmawati Andin Ajeng
Published: August 2020

ABSTRAKPerawatan payudara bertujuan untuk memelihara kebersihan payudara agar terhindar dari infeksi, meningkatkan produksi ASI dengan merangsang kelenjar-kelenjar air susu melalui pemijatan, mencegah bendungan ASI, menguatkan puting.Perawatan payudara pada ibu menyusui dilakukan 2 kali sehari pagi dan sore sejak hari kedua pasca melahirkan. Penelitian ini bertujuan untuk mengetahui karakteristik ibu nifas tentang perawatan payudara di BPM Umi Lestari CW, A.Md.Keb Desa Plesungan Kecamatan Kapas Kabupaten Bojonegoro. Penelitian ini menggunakan metode deskriptif.Dari hasil penelitian didapatkan bahwa dari 30 responden sebagian besar responden memiliki karakteristik dalam kategori cukup, yakni sebanyak 12 orang (53,9%), karaktreistik dalam kategori baik sebanyak 10 orang (30,3%) dan karakteristik dalam kategori kurang sebanyak  8 orang (15,7%). Kata Kunci       : Ibu Nifas, Perawatan PayudaraABSTRACTBreast care aims to maintain breast hygiene so as to avoid infection, increase milk production by stimulating the glands of milk through massage, preventing milk dams, strengthening the nipples. Breast care for nursing mothers is done twice a day morning and evening since the second day after giving birth. This study aims to determine the characteristics of puerperal women about breast care in BPM Umi Lestari CW, A.Md.Keb Plesungan Village, Kapas District, Bojonegoro Regency. This research uses a descriptive method. From the results of the study found that of the 30 respondents most respondents had characteristics in the sufficient category, namely as many as 12 people (53.9%), characteristics in the good category as many as 10 people (30.3%) and characteristics in the category of less as many as 8 people ( 15.7%). Keywords         : Postpartum Mother, Breast Care
Pengalaman Masyarakat Sebagai Penolong Awam Dalam Memberikan Pertolongan Kepada Korban Kecelakaan Lalu Lintas Kabupaten Bojonegoro
Authors: Khayudin Bayu Akbar
Published: August 2020

Fenomena pemberian pertolongan pertama di tempat kejadian pada korban kecelakaan lalu lintas jarang dilakukan langsung oleh petugas kesehatan ataupun masyarakat sekitar lokasi kejadian sebagai orang yang terlatih. Orang awam yang sering dijumpai dan memberikan pertolongan pertama adalah Masyarakat. Tujuan penelitian ini yaitu untuk mengeksplorasi makna pengalaman masyarakat sebagai orang awam dalam menolong korban kecelakaan Lalu lintas di Kabupaten Bojonegoro. Desain penelitian kualitatif dengan pendekatan fenomenologi intepretatif. Pengumpulan data menggunakan metode wawancara mendalam dengan panduan wawancara semi terstruktur yang melibatkan empat partisipan. Hasil penelitian ini mendapatkan 3 tema : (!) Menolong Korban Dengan Semampunya (2) Merasakan ketakutan saat menolong korban (3) Berharap adanya kerjasama dengaan tim penolong dalam menjalankan system pertolongan korban kecelakaan. Kesimpulan penelitian ini yaitu masyarakat mengharapkan adanya kerja sama tim penolong dalam menjalankan system pertolongan korban kecelakaan. pelatihan serta kemudahan dalam menghubungi petugas sangat diharapkan oleh masyarakat untuk menyelamatkan korban kecelakaan lalu lintas dengan kemampuan yang lebih baik
Synergistic Effect of the Cationic Peptide Hominin and a New Disinfectant Based on Isoquinoline on Formation of Biofilms in Multidrug-Resistant Staphylococci
Authors: Kononova L. I. , Pyankov I. A. , Smolyak A. A. , Shklyaev Yu. V. , Korobov V. P.
Published: August 2020

The growing threat of proliferation of biofilm-forming hospital strains of coagulase-negative staphylococci resistant to antibiotics determines the need for an urgent search for new effective antibacterial compounds, as well as the development of methods for the combined use of traditional and alternative antibiotics. The article presents the results of a study of the combined effect of the drug «SA» — a new synthetic derivative of the alkaloid isoquinoline and a low-molecular-weight cationic peptide of the lantibiotic family hominin, which inhibits the development of bacterial biofilms of the clinical strain of Staphylococcus haemolyticus and its vancomycin-resistant isolates. It was found that combinations of these compounds have a synergistic effect that suppresses the formation of biofilms of both studied strains of staphylococci at reduced concentrations of these antibacterial compounds.
Study of the Antibacterial Activity of Phenylacetic Acid Derivative Against the Causative Agent of Cholera
Authors: Selyanskaya N. A. , Golovin S. N.
Published: August 2020

The in vitro and in vivo activity of a phenylacetic acid derivative, diclofenac, was studied against V.cholerae O1 El Tor strains and biofilms formed by them. In the presence of a subinhibitory concentration of diclofenac (250 mg/l), a 4-fold decrease in the values of the minimum inhibitory concentrations of furazolidone and chloramphenicol was found in 30% and 100% of the strains resistant to these drugs, and a significant increase in the diameters of growth inhibition zones around discs with chloramphenicol. furazolidone, streptomycin (for all strains) and doxycycline (for two strains) in comparison with the control. Furazolidone, nalidixic acid, chloramphenicol, streptomycin, to which the infecting strain was resistant, were used in in vivo experiments in combination with diclofenac for the treatment of white mice; in the experimental group the number of surviving animals increased to 80% in comparison with monotherapy with these drugs (50% or less). The subinhibitory concentration of diclofenac did not have a pronounced effect on the antibiotic sensitivity of biofilms. The study using transmission electron microscopy method on the biofilm of the V.cholerae O1 El Tor 19667 strain after exposing it to diclofenac (250 mg/l) for 120 h revealed signs of destruction of the exopolysaccharide matrix. These results indicate the prospects for studying this group of drugs, as well as others in order to develop new ways to overcome bacterial resistance.
Pathogenetic Therapy of Patients with Recurrent Genital Herpes
Authors: Logvina L. L. , Bayram D. N. , Kambachokova Z. A. , Shavaeva F. V. , Krymshokalova Z. S. , Sarbasheva M. M. , Kardanova M. Kh. , Iosipchuk K. O.
Published: August 2020

Evaluation of the effectiveness of aminophthalhydroside in the complex treatment of patients with recurrent genital herpes was carried out. The efficacy of the drug was assessed by clinical, biochemical, and immunological criteria. The inclusion of aminophthalhydrazide in the complex therapy of patients with recurrent herpesvirus infection led to an earlier relief of clinical manifestations of the disease, an increase in the relapse period, a decrease in lipid peroxidation products in the blood plasma, an increase in the content of antioxidant defense components, and correction of immunological disorders.
Primary tumor cell cultures: сurrent methods of obtaining and subcultivation
Authors: Mezhevova I. V. , Sitkovskaya A. O. , Kit O. I.
Published: August 2020

Over the past decades, transplantable cell lines have been an affordable model for studying the biology and effect of chemotherapeutic drugs on tumors. However, numerous studies have shown that these cell lines are not heterogeneous enough and cannot reflect the drug resistance of tumors that occurs in some patients. Primary cell line cultures isolated from solid tumors have become widespread in personalized cancer therapy. This review discusses the basic methods for the preparation and cultivation of primary cell lines. A brief description is given of the methods for the disaggregation of tumor material using enzymatic, chemical and mechanical dissociation. The systems of cultivation of primary cell cultures. The selection of an appropriate dissociation method and cultivation is important to preserve the benefits of primary culture in preclinical studies.
Terug naar toen: Baumans cultuursociologische overpeinzingen
Authors: Swartjes Britt
Published: August 2020

_Sketches in the Theory of Culture_ (2018) biedt een uniek inzicht in Zygmunt Baumans denken en een semiotische theorie van cultuur, toegepast op maatschappelijke problematiek van Polen in de jaren zestig.
Impact of Leadership Styles of Principals on Teacher Educants: A Study of Colleges of Education in Northern Ghana
Authors: Sulemana Iddrisu , Shanunu Zakaria , Nuhu Alhassan Imoro
Published: August 2020

The study examined the impact of leadership styles of Principals of Colleges of Education
in Northern Ghana. A descriptive survey research design was used together with a
convenient sampling technique. Using a structured questionnaire, data were gathered
from (one hundred) 100 Teacher educants and Principals from the Colleges of education
in Northern Ghana. The Likert rating scale was adopted to indicate the extent of agreement
or disagreement. The findings indicated that the majority of the respondents agreed their
principals have a good relationship with teacher educants. The personality traits exhibited
by the Principals in the Colleges of education in Northern Ghana varied and each of the
leadership styles exhibited exerted positive but insignificant effect on teacher educants
performance. It is being recommended that to promote teacher educants satisfaction at the
workplace, principals must create a congenial climate in their respective colleges to ensure
that teacher educants can share and freely express their opinions. Pre-service and in-service
training programmes must be organized periodically leading to improved performance
Torsional Oscillations in Dynamo Models with Fluctuations and Potential for Helioseismic Predictions of the Solar Cycles
Authors: Pipin Valery V. , Kosovichev Alexander G.
Published: August 2020

Using a nonlinear mean-field solar dynamo model, we study relationships between the amplitude of the “extended” mode of migrating zonal flows (“torsional oscillations”) and magnetic cycles, and investigate whether properties the torsional oscillations in subsurface layers and in the deep convection zone can provide information about the future solar cycles. We consider two types of dynamo models: models with regular variations of the α-effect, and models with stochastic fluctuations, simulating “long-memory” and “short-memory” types of magnetic activity variations. It is found that torsional oscillation parameters, such the zonal acceleration, show a considerable correlation with the magnitude of the subsequent cycles with a time lag of 11–20 yr. The sign of the correlation and the time-lag parameters can depend on the depth and latitude of the torsional oscillations as well as on the properties of long-term (“centennial”) variations of the dynamo cycles. The strongest correlations are found for the zonal acceleration at high latitudes at the base of the convection zone. The model results demonstrate that helioseismic observations of the torsional oscillations can be useful for advanced prediction of the solar cycles, 1–2 sunspot cycles ahead.
Opacity-driven Convection and Variability in Accretion Disks around Supermassive Black Holes
Authors: Jiang 姜 Yan-Fei 燕 飞 , Blaes Omer
Published: August 2020

We study the structure of accretion disks around supermassive black holes in the radial range of –100 gravitational radii, using a three-dimensional radiation magnetohydrodynamic simulation. For typical conditions in this region of active galactic nuclei (AGNs), the Rosseland mean opacity is expected to be larger than the electron scattering value. We show that the iron opacity bump causes the disk to be convectively unstable. Turbulence generated by convection puffs up the disk due to additional turbulent pressure support and enhances the local angular momentum transport. This also results in strong fluctuations in surface density and heating of the disk. The opacity drops with increasing temperature and convection is suppressed. The disk cools down and the whole process repeats again. This causes strong oscillations of the disk scale height and luminosity variations by more than a factor of ≈3–6 over a few years’ timescale. Since the iron opacity bump will move to different locations of the disk for black holes with different masses and accretion rates, we suggest that this is a physical mechanism that can explain the variability of AGN with a wide range of amplitudes over a timescale of years to decades.
SCUBA2 High Redshift Bright Quasar Survey: Far-infrared Properties and Weak-line Features
Authors: Li 李 Qiong 琼 , Wang 王 Ran 然 , Fan Xiaohui , Wu 吴 Xue-Bing 学兵 , Jiang 江 Linhua 林华 , Bañados Eduardo , Venemans Bram , Shao 邵 Yali 亚莉 , Li 李 Jianan 佳男 , Zhang 张 Yunhao 云皓 , Zhang 张 Chengpeng 程鹏 , Wagg Jeff , Decarli Roberto , Mazzucchelli Chiara , Omont Alain , Bertoldi Frank
Published: August 2020

We present a submillimeter continuum survey (“SCUBA2 High rEdshift bRight quasaR surveY,” hereafter SHERRY) of 54 high-redshift quasars at 5.6 < z < 6.9 with quasar bolometric luminosities in the range of (0.2–5) × 1014
L
⊙, using the Submillimetre Common-User Bolometer Array-2 (SCUBA2) on the James Clerk Maxwell Telescope. About 30% (16/54) of the sources are detected with a typical 850 μm rms sensitivity of 1.2 mJy beam−1 (S

ν,850 μm = 4–5 mJy, at >3.5σ). The new SHERRY detections indicate far-infrared (FIR) luminosities of 3.5 × 1012 to 1.4 × 1013
L
⊙, implying extreme star formation rates of 90–1060 M
⊙ yr−1 in the quasar host galaxies. Compared with z = 2–5 samples, the FIR-luminous quasars (L
FIR > 1013
L
⊙) are rarer at z ∼ 6. The optical/near-infrared spectra of these objects show that 11% (6/54) of the sources have weak Lyα emission-line features, which may relate to different subphases of the central active galactic nuclei (AGNs). Our SCUBA2 survey confirms the trend reported in the literature that quasars with submillimeter detections tend to have weaker ultraviolet (UV) emission lines compared to quasars with nondetections. The connection between weak UV quasar line emission and bright dust continuum emission powered by massive star formation may suggest an early phase of AGN–galaxy evolution, in which the broad-line region is starting to develop slowly or is shielded from the central ionization source, and has unusual properties such as weak-line features or bright FIR emission.
Does GW190425 Require an Alternative Formation Pathway than a Fast-merging Channel?
Authors: Safarzadeh Mohammadtaher , Ramirez-Ruiz Enrico , Berger Edo
Published: August 2020

The LIGO/Virgo Scientific Collaboration (LVC) recently announced the detection of a compact object binary merger, GW190425, with a total mass of

M
⊙ and individual component masses in the range of about 1.1–2.5 M
⊙. If the constituent compact objects are neutron stars, then the total mass is five standard deviations higher than the mean of 2.66 ± 0.12 M
⊙ for Galactic binary neutron stars. LVC suggests that the nondetection of such massive binary neutron star (BNS) systems in the Galaxy is due to a selection effect. However, we are unable to reconcile the inferred formation efficiency from the reported merger rate,

yr−1 Gpc−3, with predictions from our own study for fast-merging BNS systems. Moreover, the comparable merger rates of GW190425 and GW170817 are possibly in tension with our results for two reasons: (i) more massive systems are expected to have lower formation rates, and (ii) fast-merging channels should constitute ≲10% of the total BNS systems if case BB unstable mass transfer is permitted to take place as a formation pathway. We argue that, to account for the high merger rate of GW190425 as a BNS system, (i) our understanding of NS formation in supernova explosions must be revisited, or (ii) more massive NSs must be preferentially born with either very weak or very high magnetic fields so that they would be undetectable in the radio surveys. Perhaps the detected massive NSs in NS–white dwarf binaries are our clues to the formation path of GW190425 systems.
Steady Wind-blown Cavities within Infalling Rotating Envelopes: Application to the Broad Velocity Component in Young Protostars
Authors: Liang Lichen , Johnstone Doug , Cabrit Sylvie , Kristensen Lars E.
Published: August 2020

Wind-driven outflows are observed around a broad range of accreting objects throughout the universe, ranging from forming low-mass stars to supermassive black holes. We study the interaction between a central isotropic wind and an infalling, rotating envelope, which determines the steady-state cavity shape formed at their interface under the assumption of weak mixing. The shape of the resulting wind-blown cavity is elongated and self-similar, with a physical size determined by the ratio between wind ram pressure and envelope thermal pressure. We compute the growth of a warm turbulent mixing layer between the shocked wind and the deflected envelope, and calculate the resultant broad-line profile, under the assumption of a linear (Couette-type) velocity profile across the layer. We then test our model against the warm broad velocity component observed in CO J = 16–15 by Herschel/HIFI in the protostar Serpens-Main SMM1. Given independent observational constraints on the temperature and density of the dust envelope around SMM1, we find an excellent match to all its observed properties (line profile, momentum, temperature) and to the SMM1 outflow cavity width for a physically reasonable set of parameters: a ratio of wind to infall mass flux of ≃4%, a wind speed of v
w ≃ 30 km s−1, an interstellar abundance of CO and H2, and a turbulent entrainment efficiency consistent with laboratory experiments. The inferred ratio of ejection to disk accretion rate, ≃6%–20%, is in agreement with current disk wind theories. Thus, the model provides a new framework to reconcile the modest outflow cavity widths in protostars with large observed flow velocities. Being self-similar, it is applicable over a broader range of astrophysical contexts as well.
Eruptive–Impulsive Homologous M-class Flares Associated with Double-decker Flux Rope Configuration in Minisigmoid of NOAA 12673
Authors: Mitra Prabir K. , Joshi Bhuwan , Veronig Astrid M. , Chandra Ramesh , Dissauer K. , Wiegelmann Thomas
Published: August 2020

We present a multiwavelength analysis of two homologous, short-lived, impulsive flares of GOES class M1.4 and M7.3 that occurred from a very localized minisigmoid region within the active region NOAA 12673 on 2017 September 7. Both flares were associated with initial jetlike plasma ejection that for a brief amount of time moved toward the east in a collimated manner before drastically changing direction toward the southwest. Nonlinear force-free field extrapolation reveals the presence of a compact double-decker flux rope configuration in the minisigmoid region prior to the flares. A set of open field lines originating near the active region that were most likely responsible for the anomalous dynamics of the erupted plasma gave the earliest indication of an emerging coronal hole near the active region. The horizontal field distribution suggests a rapid decay of the field above the active region, implying high proneness of the flux rope system toward eruption. In view of the low coronal double-decker flux ropes and compact extreme ultraviolet brightening beneath the filament, along with associated photospheric magnetic field changes, our analysis supports the combination of initial tether-cutting reconnection and subsequent torus instability for driving the eruption.
Identification of Delia spp. (Robineau-Desvoidy) (Diptera, Anthomyiidae) and its cruciferous hosts in Mexico
Authors: Meraz-Álvarez Ricardo , Bautista-Martínez Néstor , Illescas-Riquelme Carlos Patricio , González-Hernández Héctor , Valdez-Carrasco Jorge Manuel , Savage Jade
Published: August 2020

Soil pests of cruciferous crops in Mexico have been gaining importance in recent years; such is the case of Delia spp. (Robineau-Desvoidy) (Diptera, Anthomyiidae), of which, to date, there are no studies on the correct identification of associated species, as well as the range of hosts. In an integrated pest management program, it is essential to know this information to design and implement adequate phytosanitary measures. Plants infested by Delia spp. were collected in the states of Guanajuato, Puebla, and Mexico from June to November 2017 and March to December 2018 in commercial plantations of cruciferous crops (Brassica oleracea L. var. italica, botrytis and capitata), B. napus L., and Raphanus sativus L.) as well as some cruciferous weeds (R. raphanistrum L., Sisymbrium irio L., B. campestris L., Capsella bursa-pastoris L., and Lepidium virginicum L.) in the edges of these crops. The two species found in this study, Delia planipalpis (Stein) and Delia platura (Meigen), identified using male genitalia was corroborated by molecular techniques. Both species emerged from all the sampled hosts, except for C. bursa-pastoris and L. virginicum. The association of the two species in cruciferous crops and weeds, provides valuable information for the management of these insects not only in cruciferous crops but other ones that are strongly attacked by D. platura.
Sexual Satisfaction Among Infertile Couples: Demographics and Psychosocial Health Factors
Authors: Mahadeen Alia Ibrahim , Hamdan-Mansour Ayman M. , Habashneh Samira A. , Dardas Latefa Ali
Published: August 2020

The purpose of the current study was to explore sexual satisfaction among infertile couples in Jordan and its associations with psychosocial and sociodemographic factors. Using a descriptive correlational design, 248 infertile couples from outpatient clinics were recruited and filled out a questionnaire on sexual satisfaction, in addition to perceived social support, depressive symptoms, psychological stress, coping skills, optimism, life satisfaction, and sociodemographics. Sexual satisfaction was significantly and positively correlated with perceived social support, optimism, life satisfaction, and coping. Stronger association was observed between sexual satisfaction and optimism. No difference was found in sexual satisfaction in relation to participants' gender, age, working status, or education. This study highlights the importance of building mental health nurses' competence to provide education and counseling on sexuality to improve the quality of life of infertile couples and optimize their sexual wellness. The most recent guidelines for psychosocial care for infertile couples are discussed. [
Journal of Psychosocial Nursing and Mental Health Services, 58
(9), 40–47.]
Gene Therapy in Anderson-Fabry Disease. State of the Art and Future Perspectives
Authors: Spiniello Giorgio , Verrillo Federica , Ricciolino Riccardo , Prozzo Dario , Tuccillo Andrea , Caiazza Martina , Rubino Marta
Published: August 2020

Anderson-Fabry disease (AFD) is an X-linked lysosomal storage disorder caused by a deficiency of the lysosomal enzyme, agalactosidase A. The inadequate enzymatic activity leads to systemic storage of glycosphingolipids, mostly globotriaosylceramide, in the lysosomes. As of now, enzyme replacement therapy is the only approved treatment for AFD. However, it does not induce a complete and lasting response in several clinical contexts. Genemediated enzyme replacement is an emerging approach that could overcome these limits. The single gene nature of AFD enhances the possibility to transfect and modify a small number of cells, making them capable to affect the correction of a larger number of cells. This review summarizes the history and the state of the art of gene therapy in AFD, showing potential benefits and limits.
COVID-19: measures to protect older adults from SARS-CoV-2 infection
Authors: Ayenigbara Israel Oluwasegun , Moronkola Olawale Akanbi
Published: August 2020

As every nation battles the coronavirus disease 2019 (COVID-19) pandemic comprehensively, older adults are by far the most affected group in terms of morbidity and mortality rates. Particularly individuals in the age range of >60 years and with comorbidities and other geriatric conditions are at heightened risk of complications from COVID-19 compared to any other age groups in the world. The time between the infection of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV- 2) and the manifestation of the symptoms is between two to twelve days. Typical symptoms of COVID-19 are high temperature, dry cough, and breathing difficulties in complicated cases, while new evidence shows atypical presentations of COVID-19 symptoms in older adults, and are highlighted in this review. From this synopsis, we deduced that firstly, the severity of COVID-19 among older adults is because of biological (dwindling immunity with old age), socio-economic (poverty and over-stretched health system) and physical reasons (frailty and comorbidities). Secondly, there is an upsurge in the rates of transmission and COVID-19 fatalities in nursing homes globally. Lastly, to abate the spread of SARS-CoV-2 among older adults, strict adherence to physical distancing, frequent hand hygiene and respiratory hygiene, frequent disinfection of surfaces, stoppage to unnecessary travel and nonessential hospital’s visitations, appropriate use of face masks, healthy life style choices, proper identification and isolation of infected older adults, assistance and support for older adults in the community, and prevention of infections in nursing homes should all essentially be implemented globally. It is recommended that maximum compliance to measures provided in this review should be ensured and implemented. Governments, civil societies and general public should provide supports for older adults during this COVID-19 pandemic period, and new researches should look more into the global severity of COVID-19 on nursing homes and the geriatric populations generally to get progressively feasible exact information that will enable informed preventive choices.