bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of humate and controlled released NPK fertilizers (NPK-CRF) on rice yield and soil fertility of intensive alluvial soils
Authors: Thu Tat Anh , Thuong Bui Trieu , Minh Vo Quang
Published: December 2022

The study aims to assess the effect of mixed fertilizers, including controlled slow-release NPK (NPK-CRF) and urea, potassium humate fertilizers, on soil fertility and rice yield. The on-Farm Trials experiment was carried out on alluvial soil, with two models corresponding to two farming techniques: (i) Traditional fertilization, applying conventional fertilizers with the formula 92.2 N–82.8 P2O5–22.8 K2O kg/ha; (ii) New generation fertilizers (NPK-CRF, urea humate, and potassium humate) with the formula 50.1 N–39.9 P2O5–30.0 K2O. Each pattern was repeated three times, corresponding to 3 farmers. Each household's area is 1,000m2, cultivating continuously through three seasons of Winter-Spring (WS), Summer-Autumn (SA), and Autumn-Winter (AW) in Chau Thanh A district, Hau Giang province. The results showed that the new generation fertilizer application significantly improved rice yield and yield composition of the Winter-Spring cropping season (6.92 tons/ha), Summer-Autumn (5.94 tons/ha), and Autumn-Winter (6.15 tons/ha), which are different from farmers' fields. Furthermore, the combined application of NPK-CRF, urea-humate, and K-humate fertilizers for rice in SA and AW crops significantly reduced the total acid content, Al3+ exchange in the soil, and improved soil fertility of pH, N, and available P, organic matter (%C). However, there was no difference in soil's physical properties over the three farming seasons. Finally, adding humic acid to controlled-release fertilizer can improve soil fertility, and increase yield and yield components, nitrogen uptake, enhance nitrogen usage efficiency, all of which have positive yield and soil consequences.
Pancreatic KCa3.1 channels in health and disease
Authors: Soret Benjamin , Hense Jurek , Lüdtke Simon , Thale Insa , Schwab Albrecht , Düfer Martina
Published: December 2022

Ion channels play an important role for regulation of the exocrine and the endocrine pancreas. This review focuses on the Ca2+-regulated K+ channel KCa3.1, encoded by the KCNN4 gene, which is present in both parts of the pancreas. In the islets of Langerhans, KCa3.1 channels are involved in the regulation of membrane potential oscillations characterizing nutrient-stimulated islet activity. Channel upregulation is induced by gluco- or lipotoxic conditions and might contribute to micro-inflammation and impaired insulin release in type 2 diabetes mellitus as well as to diabetes-associated renal and vascular complications. In the exocrine pancreas KCa3.1 channels are expressed in acinar and ductal cells. They are thought to play a role for anion secretion during digestion but their physiological role has not been fully elucidated yet. Pancreatic carcinoma, especially pancreatic ductal adenocarcinoma (PDAC), is associated with drastic overexpression of KCa3.1. For pharmacological targeting of KCa3.1 channels, we are discussing the possible benefits KCa3.1 channel inhibitors might provide in the context of diabetes mellitus and pancreatic cancer, respectively. We are also giving a perspective for the use of a fluorescently labeled derivative of the KCa3.1 blocker senicapoc as a tool to monitor channel distribution in pancreatic tissue. In summary, modulating KCa3.1 channel activity is a useful strategy for exo-and endocrine pancreatic disease but further studies are needed to evaluate its clinical suitability.
Terrorists’ Violence Threats and Coping Strategies: A Phenomenological Approach of Former FATA, Pakistan
Authors: Alam Jan , Ullah Nazir , Rasool Hidayat
Published: December 2022

Terrorism is a global phenomenon that constantly challenges human survival. Based on the social structure, human beings adopt different strategies to overcome its negative consequences on their mind and behavior. Coping strategies and those processes essential for adjustment and survival illustrate how individuals perceive, consider, deal with, and realize a stressful situation in the era of terrorism. The study focuses on exploring coping strategies and avoidance of terrorism impacts. This research study was qualitatively designed to explore the coping strategies adaptation and their influence on the former FATA individuals during the wave of terrorism in the region. The study was undertaken in five districts of erstwhile FATA, including Dara Adam Khel, Orakzai Agency, Khyber Agency, and North and South Waziristan agency. A sample size of twenty-five (25) participants was purposively selected and interviewed, ten (10) focused group discussions (FGDs) were done from each district, and the other 50 participants were chosen for ten (10) FGDs. The collected data were analyzed via the thematic analysis technique. The findings revealed that coping strategies included four different phases: the welcome, resistance, acceptance, surrender, and flee phases for overcoming threats of terrorism. Furthermore, it was also found that fear of terrorism had strongly influenced the individuals’ physical, socio-economic, psychological, emotional stress and fear, education, and social integration. The study recommended that social integration and solidarity among the people, as well as their cooperation with the government, can eliminate the threat of terrorism.
Photocatalytic degradation of naproxen using single-doped TiO2/FTO and co-doped TiO2-VO2/FTO thin films synthesized by sonochemistry
Authors: Orozco-Gonzalez Luis Rene , Acosta-Najarro Dwight Roberto , Magaña-Zavala Carlos Raúl , Tavizón-Pozos Jesus Andres , Cervantes-Cuevas Humberto , Chavez-Esquivel Gerardo
Published: December 2022

Single-doped TiO2/FTO and co-doped TiO2-VO2/FTO thin films were prepared by sonochemistry and spray pyrolysis deposition on FTO substrates. The co-deposition of TiO2-VO2 on FTO significantly changed the morphological, structural, optical, and photocatalytical properties compared to the single-deposition. X-ray diffraction and HRTEM results showed polycrystalline film structures composed of SnO2-tetragonal from FTO, anatase-TiO2, rutile-TiO2, and monoclinic-VO2 phases. The co-deposition technique increases the particle size distribution by approximately two times compared to simple deposition. The single-doped TiO2/FTO thin film had a 15% higher bandgap than the co-doped TiO2-VO2/FTO thin film, and the electrical resistivity calculated from the van der Pauw method was 55.3 MΩ sq−1 for the TiO2-VO2/FTO co-doped thin film, 2.7 times lower than that obtained for the TiO2/FTO thin film. Single-doped TiO2/FTO and co-doped TiO2-VO2/FTO thin films presented pseudo-first-order reactions at pH 6.5, with kinetic constants of 0.026 and 0.015 min−1, respectively. This behavior is related to the production of inactive or less active aggregates by the addition of vanadium during the co-doping process, which led to lattice contraction, which encouraged the formation of the rutile phase rather than the anatase phase. However, the co-doped thin film can modify the metal-insulator transition compared to the single-doped TiO2/FTO thin film. Furthermore, co-deposition decreased the bandgap value by 16% compared to single-deposition thin film. In this sense, co-doped TiO2-VO2/FTO thin films inhibited the recombination of photogenerated carriers and the formation of reactive oxygen species involved in the photocatalytic degradation of naproxen.
The prosodic foot beyond prosodic prominence: a preliminary survey
Authors: Culhane Kirsten
Published: December 2022

This paper presents a preliminary survey of foot-sensitive phenomena and foot structure separate from prosodic prominence or classifications such as ‘iambic’ and ‘trochaic’. It considers the evidence for and structure of the foot in a sample of 30 languages which demonstrate at least one foot-sensitive phenomenon which cannot be attributed to prosodic prominence. It finds that in the sample, there is considerable diversity in terms of: a) the type of evidence for and role played by the foot, b) the extent to which there is evidence for the foot, and c) the segmental structure of the foot. These findings demonstrate that the role of the foot is more diverse than often characterised. The findings of this paper also demonstrate that cross-linguistic differences between foot structures are more fine-grained than differences in the distribution of prosodic prominence or syllable weight; accounting for the diversity observed requires reference to the segmental structure of feet. In light of these findings, this paper calls for more examination of the prosodic foot separate from prosodic prominence, and which takes into consideration the variables of cross-linguistic diversity documented here.
Bayesian VARs and prior calibration in times of COVID-19
Authors: Hartwig Benny
Published: December 2022

This paper investigates the ability of several generalized Bayesian vector autoregressions to cope with the extreme COVID-19 observations and discusses their impact on prior calibration for inference and forecasting purposes. It shows that the preferred model interprets the pandemic episode as a rare event rather than a persistent increase in macroeconomic volatility. For forecasting, the choice among outlier-robust error structures is less important, however, when a large cross-section of information is used. Besides the error structure, this paper shows that the standard Minnesota prior calibration is an important source of changing macroeconomic transmission channels during the pandemic, altering the predictability of real and nominal variables. To alleviate this sensitivity, an outlier-robust prior calibration is proposed.
İş yaşam kalitesi ve kurumsal sosyal sorumluluk algısının işe adanmışlık üzerindeki etkisinin incelenmesi: Zincir otel işletmeleri üzerine bir araştırma
Authors: ÖKSÜZ Sefa , ERKILIÇ Eren
Published: December 2022

İnsan kaynağı konaklama işletmelerinde hizmet kalitesini belirleyen önemli bir faktör olmakla birlikte, işletmelerin başarısında kilit role sahip olarak rekabet avantajı elde etmelerini sağlamaktadır. Araştırmacılar tarafından son yıllarda sıklıkla incelenen işe adanmışlık kavramı insan kaynağının üretkenliğini ve verimliliğini artırmada etkili olan bir konudur. İşe adanmış iş görenler işletmelere rekabet ve maliyet avantajı sağlarken hizmet kalitesinin de artmasına katkı sağlamaktadır. Bu kapsamda zincir otel işletmeleri iş görenlerinin işe adanmışlıklarını artırmanın bir yolunun da iş yaşam kalitesi ve kurumsal sosyal sorumluluk algısı ile ilişkili olduğu düşünülmektedir. Bu araştırma, iş yaşam kalitesi ve kurumsal sosyal sorumluluk algısının işe adanmışlık üzerindeki etkisini incelemek amacıyla, Trabzon’daki zincir otel işletmesi iş görenleri üzerine gerçekleştirilmiştir. Trabzon’daki zincir otel işletmesi iş görenlerinden 343 geçerli anket elde edilmiştir. Araştırma modeline uygun olarak iş yaşam kalitesi, kurumsal sosyal sorumluluk algısı ve işe adanmışlık arasındaki ilişkiyi belirlemek için korelasyon analizi ve kavramların neden-sonuç ilişkini belirmek için regresyon analizi yapılmıştır. Yapılan korelasyon analizi bulgularına göre iş yaşam kalitesi ve işe adanmışlık arasında istatistiksel olarak anlamlı, pozitif yönde ve orta düzeyde bir ilişki olduğu; kurumsal sosyal sorumluluk algısı ile işe adanmışlık arasında anlamlı, pozitif yönde ve orta düzeyde bir ilişki olduğu tespit edilmiştir. Regresyon analizi sonuçlarına göre iş yaşam kalitesinin ve kurumsal sosyal sorumluluk algısının işe adanmışlık üzerinde istatistiksel olarak anlamlı bir etkisi olduğu sonucuna ulaşılmıştır. Sonuç olarak iş görenlerin iş yaşam kalitesi ve kurumsal sosyal sorumluluk algılarının düzeylerinin yükselmesi işe adanmışlıklarını artırdığı tespit edilmiştir.
Main determinants of house prices: Effects of construction cost and house sales to foreigners
Authors: ALKAN Ufuk
Published: December 2022

Housing prices have increased worldwide with the increase in commodity prices. They have become a primary investment tool most consumers prefer, especially to protect themselves from inflation. One of the main questions is which macroeconomic factors affect the housing price index, especially the increase in the number of houses sold to foreigners and the increase in construction costs. The study will answer whether the increase in housing costs or the increase in sales to foreigners causes an increase in housing prices. The variables in the study consist of macroeconomic variables that were mostly included in previous studies. Data from January 2015 to March 2022 consisted of 87-period data. Time series analysis has been tried to be explained with the help of the ARDL model by performing a boundary test. In the model, all variables were significant, but a long-term relationship was found, not a short-term one. Tests have demonstrated the model's accuracy for deviation from basic assumptions and structural break tests. Taking the logarithms of the variables in the model makes it possible to interpret them flexibly. In this context, contrary to expectations, it was determined that house sales to foreigners decreased the house price index, and the biggest reason for the increase in house prices was the cost increases that took place worldwide. Other variables that increase and decrease the housing price index are interpreted, and suggestions are made to solve the housing problem. It is considered that the model gives an idea to understand the increase in housing prices, but other social factors should also be considered for housing demand.
Causality test among foreign direct investment, trade openness and economic growth: recent evidence from BRICS and MINT countries
Authors: KÜÇÜKSAKARYA Sevilay
Published: December 2022

This study attempts to find new evidence of causality between foreign direct investment, trade openness, and economic growth for BRICS and MINT countries between 1990-2021 using the Dumitrescu-Hurlin panel causality test. We first check whether there is a cross-sectional dependence between the countries using different cross-sectional dependence tests. After we find out there is cross-sectional dependence, we perform the CIPS unit root test. All variables are stationary at their first differences, so we applied the Dumitrescu-Hurlin panel causality test. There is bi-directional causality between trade openness and economic growth only for MINT countries. For BRICS, we found unidirectional relationships between economic growth and foreign direct investment and trade openness to economic growth. There is a unidirectional relationship from trade openness to foreign direct investment for both country groups.
Efficacy of metformin versus sulfonylurea derivative in HNF4A-MODY
Authors: Oosterom Nicole , den Braber Niala , Laverman Gozewijn D
Published: December 2022

This study compares the effects of metformin, sulfonylurea derivative (SU) and no treatment in HNF4A-MODY on glycemic control. In two patients with HNF4A-MODY, we changed the existing metformin treatment to SU derivative. The effect on the glycemic control was registered with a Freestyle Libre Flash glucose monitoring device. Each treatment period had a duration of 2 consecutive weeks, and in between, an intermediate period without medication. Data from the first 2 days after changing medications were excluded. We calculated time in range (TIR), and differences in the mean glucose level were tested with a one-way ANOVA test. The 24-h average glucose levels were significantly lower with either metformin (7.7 mmol/L; P < 0.001 and 6.3 mmol/L; P < 0.001) or gliclazide (7.6 mmol/L; P < 0.001 and 5.8 mmol/L; P < 0.001) compared to no treatment (9.4 and 8.9 mmol/L). The TIR with metformin or gliclazide was higher than without treatment (patient 1: 87 and 83 vs 61% and patient 2: 83 and 93 vs 67%). Treatment with either metformin or gliclazide effectively decreases blood glucose, rendering both drugs appropriate for treating HNF4A-MODY.

Learning points

HNF4A-MODY has a mild phenotype.

Blood glucose was responsive to long-term metformin treatment in HNF4A-MODY.

Metformin and gliclazide seem appropriate treatments for HNF4A-MODY.
Incidental finding of non-alcoholic steatohepatitis-cirrhosis
Authors: Adrian Therese , Hornum Mads , Knop Filip Krag , Lotte Gluud Lise
Published: December 2022

A 72-year-old man with type 2 diabetes volunteered to participate in the control group of a clinical study. The study evaluated non-alcoholic fatty liver disease in patients with kidney disease. The patient was followed at a gastroenterology department due to Crohn’s disease and post-operative bile acid malabsorption. The patient had no symptoms or biochemical findings suggesting liver disease. Surprisingly, a transient elastography (FibroScan®) suggested advanced fibrosis with a median of 16.1 kPa. A liver biopsy showed non-alcoholic steatohepatitis (NASH)-cirrhosis. The diagnosis was only made incidentally and highlights how NASH-cirrhosis may be overlooked due to the lack of symptoms.

Learning points

Clinicians treating high-risk populations, including patients with type 2 diabetes and/or components of the metabolic syndrome, should be aware of the frequently occurring co-existence with non-alcoholic fatty liver disease (NAFLD) and especially non-alcoholic steatohepatitis (NASH).

Liver enzymes may be in the normal range even in people with steatosis, NASH, or even cirrhosis.

The diagnosis of NAFLD should include evaluation of hepatic fibrosis as this is the most important prognostic factor for liver-related complications and mortality.

Guidelines about systematic screening for NAFLD in patients with type 2 diabetes are incongruent.
A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction
Authors: Nakajima Rikako , Sekiya Motohiro , Furuta Yasuhisa , Miyamoto Takafumi , Sato Masashi , Fukuda Kuniaki , Hattori Keiichiro , Suehara Yasuhito , Sakata-Yanagimoto Mamiko , Chiba Shigeru , Okajima Yuka , Matsuzaka Takashi , Takase Satoru , Takanashi Mikio , Okazaki Hiroaki , Takashima Yusuke , Yuhara Mikiko , Mitani Yuta , Matsumoto Nako , Murayama Yuki , Ohyama Osawa Mariko , Ohuchi Nami , Yamazaki Daichi , Mori Sayuri , Sugano Yoko , Osaki Yoshinori , Iwasaki Hitoshi , Suzuki Hiroaki , Shimano Hitoshi
Published: December 2022

In this study, we herein describe a 47-year-old Japanese woman who manifested inheritable non-alcoholic steatohepatitis (NASH) and severe dyslipidemia. Interestingly, her NASH progression was ameliorated by treatment with a sodium–glucose co-transporter 2 (SGLT2) inhibitor. This inheritability prompted us to comprehensively decode her genomic information using whole-exome sequencing. We found the well-established I148M mutation in PNPLA3 as well as mutations in LGALS3 and PEMT for her NASH. Mutations in GCKR may contribute to both NASH and dyslipidemia. We further mined gene mutations potentially responsible for her manifestations that led to the identification of a novel M188fs mutation in MUL1 that may be causally associated with her mitochondrial dysfunction. Our case may provide some clues to better understand this spectrum of disease as well as the rationale for selecting medications.

Learning points

While the PNPLA3 I148M mutation is well-established, accumulation of other mutations may accelerate susceptibility to non-alcoholic steatohepatitis (NASH).

NASH and dyslipidemia may be intertwined biochemically and genetically through several key genes.

SGLT2 inhibitors emerge as promising treatment for NASH albeit with interindividual variation in efficacy. Genetic background may explain the mechanisms behind the variation.

A novel dysfunctional mutation in MUL1 may lead to metabolic inflexibilities through impaired mitochondrial dynamics and function.
La tradición latina en Filipinas: historia cultural y corpus textual
Authors: Donoso Isaac
Published: December 2022

En el presente trabajo se ensaya un estudio de la historia cultural de la lengua latina en las islas Filipinas, atendiendo a su uso letrado, producción escrita y conformación de una tradición neolatina en Asia, desde el siglo XVI hasta el presente. Estudiamos la implantación del sistema de enseñanza occidental y la adaptación de la cultura europea del Humanismo moderno, desde su uso y cultivo por parte de las élites coloniales, hasta su negociación, transformación y adopción por la población local, en el proceso de construcción de una nueva sociedad civil. Con este fin se relacionan obras y textos que puedan dar forma a un primer corpus textual de literatura neolatina en Filipinas. Para finales del siglo XIX es el propio José Rizal quien articula y problematiza el papel del latín en la construcción de la moderna nación, y así título latino tiene la obra más importante de Filipinas: Noli me tangere.
Principles of Construction of Hybrid Microsystems for Biomedical Applications
Authors: Dzundza B.S. , Kohut I.T. , Holota V.I. , Turovska L.V. , Deichakivskyi M.V.
Published: December 2022

The paper analyzes the existing non-invasive methods and tools for measuring and monitoring heart rate (HR), glucose saturation and human blood glucose level (BGL), shows ways of improving them to increase accuracy and expand the number of parameters obtained by these methods, which became the basis for creating a hybrid microsystem device for biomedical applications.

A block diagram of the microsystem and a prototype of software and hardware tools for continuous monitoring of heart rate, BGL, saturation level and other blood parameters by photoplethysmography (PPG) have been developed. The proposed algorithms and tools provide primary processing of signals from optical sensors, calculation of pulse wave parameters, data transmission to mobile devices and a remote server, the possibility of calibration during operation based on research results.
TÜRK VE İNGİLİZ HUKUKUNDA İŞ SÖZLEŞMESİNİN SONA ERMESİ
Authors: ORDU Ayten
Published: December 2022

Çalışmamızın konusu, Türk ve İngiliz hukukunda iş sözleşmesinin sona ermesidir. İşçinin veya işverenin iş sözleşmesini sonlandırmasının, Türk ve İngiliz Hukukunda ne şekilde ele alındığına değinilecektir. İngiliz hukukundaki Employment Rights Act 1996 ve 4857 sayılı İş Kanunundaki düzenlemeler dikkate alınacak, mevzuatta yer alan maddelerin karşılaştırılmasına yer verilerek tartışılacaktır. Çalışmamızda inceleneceği üzere; Türk ve İngiliz Hukuku bakımından, bir iş sözleşmesi iki türlü sona erdirilebilir. Bunlardan biri, genel sebeplerle sona erme, diğeri ise fesih nedeniyle sona ermedir. Ancak her iki hukuk düzeninde benzerlikler olduğu kadar, farklılıklar da mevcuttur. Çalışmamız süresince; Türk ve İngiliz Hukuku bakımından bir iş sözleşmesinin sona ermesine ilişkin olan düzenlemelere ve iki hukuk düzeni arasındaki farklara değinilecektir.
KONKORDATONUN KAMU İHALELERİNE ETKİSİ
Authors: KODAKOĞLU Mehmet
Published: December 2022

Konkordatonun amacı, borçlunun malî yapısını düzeltmesine ve varlığını devam ettirmesine imkân sağlayacak elverişli ortamın yaratılmasıdır. Ancak konkordato süreci içinde bulunan isteklilerin malî ve ekonomik yönden zayıf durumda olmaları, ihale konusu işi tamamlayabilecekleri noktasında tereddütler oluşturmaktadır.

Kamu İhale Kanunu’nun 10. maddesinde tahdidi olarak sayılan “ihale dışı bırakılma” sebeplerinden biri olarak “konkordato ilan eden” kavramı kullanılmıştır. Söz konusu kavramın, konkordato hükümlerinin düzenlendiği İcra ve İflâs Kanunu’nda bir karşılığı bulunmamaktadır. Öte yandan “konkordato ilan eden” kavramına, Kamu İhale Kanunu’ndaki ilgili düzenlemenin kaynağını oluşturan Avrupa Birliği direktiflerinde de rastlanılmamaktadır.

Bu sebeple, özellikle Kamu İhale Kurulu ve devamında idarî yargı kararla-rında sorunlara yol açtığı görülen ve hukukî bir zemine oturtulamayan “konkordato ilan eden” kavramı, yorum metodları kullanılarak 4734 sayılı Kamu İhale Kanunu ve 4735 sayılı Kamu İhale Sözleşmeleri Kanunu kapsamında ele alınmış ve konkordatonun kamu ihalelerine etkisi konusu ayrıntılı olarak incelenmiştir.
Russian chronicles and West European chivalric epics: two possible comparisons
Authors: Lukin Pavel
Published: December 2022

The article is devoted to the comparison of accounts of Russian chronicles of the pre-Mongol time and episodes from the West-European chivalrous epic. Two parallel plots are considered, in which the author sees certain similarities. First, an account of the Novgorod First Chronicle on the conflict in Novgorod in 1015, in the course of which some noble Novgorodians were killed on the order of Prince Yaroslav, and an episode from "The Song of Roland", which refers to an attempt of barons of Charlemagne to intercede for the traitor Ganelon. It is concluded that both stories are based on similar ideas. Both the words of Yaroslav in the chronicle and those of the barons in "The Song of Roland" point, first of all, not to the promise of real reward, but to the medieval warrior ethic, according to which real live soldiers were more important than regrets about losses. If losses nevertheless occurred, they still cannot be fully compensated by money, treasure, or property. Second, I compare a fragment from the Hypatian Chronicle on the Prince Igor's campaign against the Polovtsians with some scenes from Thomas Malory's "Le MorteDarthur". It turns out that they present a similar arrogant attitude of a part of the military elite (prince's retinue, knights) towards ordinary infantrymen.
The sinful state of man. A fragment from a systematic french-russian dictionary of religious lexis (part 2)
Authors: Zhukovskaia Nadezhda
Published: December 2022

This work is a continuation of the publication of separate parts of the Systematic French-Russian Dictionary of Religious Vocabulary. This article is part of a larger section, Protagonistes de la religion chretienne, which includes the topics Dieu, Etres crees, Condition pecheresse de l'homme Attitudes et qualites requises des croyants, Fideles de Dieu (de l'Eglise).As with previous posts, the main goal is to present vocabulary relevant to the topic (without pretensions to theological interpretation). In some cases, we gave as a Russian equivalent not only the lexeme of the modern Russian language, but also Church Slavonicism (if it is found among the authors of the XX-XXI centuries), which has the mark church-arch.The general topic is quite extensive, so the publication is divided into two parts: the second part will begin with the fifth paragraph, and it will include lexemes and lexical expressions denoting specific manifestations of human sinfulness.As in previous publications, examples for individual items (phrases in quotation marks), as a rule, reveal the content of the concept and illustrate the use of the lexeme in the language. In most cases, they are composed of elements (both individual lexemes and phrases) appearing in French and Russian sources, but are not direct quotations.This work has been proofread by Ph.D. Comparative Theologian, vv. teacher of the Moscow Theological Academy, Archpriest Igor Vyzhanov, to whom I express my gratitude for the thoughtful reading and comments that I took into account.
Dedicated to Vladislav A. Lektorsky’s 90th anniversary EPISTEMOLOGICAL REALISM AS A NECESSARY FOUNDATION
Authors: TRUFANOVA ELENA
Published: December 2022

Modern epistemology is undergoing some changes related to the transformations of human environment, primarily caused by digitalization. Epistemology is now dominated by two opposing trends — “naturaliziation” and “socialization”. It can be assumed that the strengthening of the “naturalization” trend in epistemology is a reaction to the previously dominant socio-constructionist trend, characterized by the rejection of epistemological realism and subjecting the concepts of truth, reality, objectivity, and knowledge to a critical revision. This approach is characterized by the idea of the dependence of knowledge on social factors, where knowledge is a tool in the hands of “power”, i.e. those social groups that have the power to compel others to their understanding of reality. Such ideas lead to the devaluation of the authority of science and knowledge in general, and are dangerous because they cause the disintegration of society, since the ability to talk about a common reality is denied and each social group has its own “knowledge” about the world. A radical gap is forming between the subject of cognition and reality, since human is dealing now with a large number of information flows, as well as digital objects and interactions, so that the knowledge obtained through direct experience is replaced by information obtained indirectly from various sources that present information in a distorted way. The modern digital environment is also problematic, because it is designed in such a way that it encloses a person within their own familiar pictures of the world, not allowing him to look beyond them and see alternative points of view. The key problem is the loss of trust — a modern subject has no criteria for selecting reliable and trustworthy sources of information, and as a result he or she does not trust anyone, which becomes a significant obstacle for obtaining knowledge. It can be concluded that the appeal to realism is important not only for solving the above mentioned epistemological problems, but also for conducting a dialogue between various social groups, which is necessary for the survival of mankind.
MAIN EXISTENTIAL CATEGORIES IN WORKS OF JOHN STEINBECK
Authors: VASILEVA Svetlana , PAVLOVA Ekaterina
Published: December 2022

This article is devoted to the works of John Steinbeck from the position of the functioning of the main existential categories or "existentials" of human Being. Existentialism is considered here as a phenomenon that has gone beyond specific philosophy and literature and entered the cultural tradition as a conglomerate of issues that directly concern anthropology. Existential categories are derived as a result of the analysis of the philosophical and cultural base of existentialism, as well as by means of addressing a specific historical situation. The term "existential" belonging to M. Heidegger is interpreted here as a "base-forming value category", "pillar for existence" and is used as an element of literary analysis. The authors identify and investigate a number of existentials characteristic for literature and capable of being modified in the angle of the plot of a particular work. As a result of the study, it is concluded that in the works of J. Steinbeck, existential categories associated with the problem of human existence in a specific situation and representing the existentials of "support and overcoming" are the most frequent. This is a "dream", "hope", "meaning of life", which is directly related to the context recreated by the author. In general, the analysis of a literary work from the angle of the functioning of existential categories allows to analyse the work in its historical and cultural terms, as well as to make a deeper and more comprehensive characteristic of a literary character.
Case report: combined pattern thyroid carcinoma
Authors: Martinez Zara , Cristiani Andrea , Centurión Dardo , Mendoza Beatriz , Mintegui Gabriela
Published: December 2022

Thyroid cancer accounts for approximately 3% of all new cancer diagnoses per year globally.1 Papillary thyroid carcinoma (PTC) is the most common type, followed by follicular thyroid carcinoma (FTC).1 Recently, the simultaneous appearance of different histological variants in the same patient has been reported, being called combined pattern thyroid cancer, mixed tumors, hybrid tumors or compound tumors of the thyroid gland.2 Epidemiologically, combined pattern cancer is reported in less than 2% of cases, it presents the same proportion in men and women, and the age of presentation is between 18 and 45 years.3 Different associations are found, including mixed carcinomas: a) medullary cancer (CMT) and PTC; b) PTC and fasciitis-like stroma; c) CPT and CFT; and even combinations of CMT, CPT and CFT.4 Several studies suggest a more aggressive clinical behavior, which may be related to the coexistence of multiple patterns of aggressive variants, with early detection and rapid and aggressive treatment being of vital importance. It is based on surgical treatment, moderate-high dose radioiodine and TSH suppression (<0.1mIU/L).4 This achieves a cure rate of up to 66% and survival three years after diagnosis of 90% and 10 years of 80% to 95%.
Historical anthropology as a modern philosophy of history and theoretical sociology: social-cultural dynamics analysis
Authors: Aytov S.
Published: December 2022

The article analyzes the impact of scientific approaches of historical anthropology as a modern philosophy of history on the theoretical sociology’s understanding of social and cultural dynamics in the planes of “local civilizations” and global. The methodology of this work includes the principles of complementarity, structure, and dialogue. In the study of the problematic field of labor, the following methods were applied: philosophical hermeneutics, systemic- structural, and interdisciplinary. Historical anthropology as a philosophical- historical discipline, that analyzes the mental- cultural horizon of causality, the essence of historical processes and their possible projection into the future has a significant potential for the understanding of global social- cultural dynamics by theoretical sociology. An important problem for its understanding is the analysis of the essence and trends of globalization and civilizational development. The scientific influence of historical anthropology as a modern philosophy of history on theoretical sociology brings to this social and humanitarian discipline conceptual approaches for researching psychological and worldview- cultural causality and the essence of processes, that are part of its problem field. Among the issues that belong to the intellectual space of theoretical and sociological studies and can be effectively investigated using the concepts of historical anthropology, the following should be noted:– the study of the mental and cultural horizon of the social dynamics of civilizational communities– understanding the humanitarian plane of the historical foundations and development trends of “local civilizations”;– study of correlation of globalization and civilizational trends of modern socio- cultural dynamics;– proposing and understanding the scenarios of further global socio- cultural development;– research of the content and features of alternative models of global socio- cultural dynamics and assessment of the probability of their implementation.Solving these cognitive issues by theoretical sociology using the conceptual approaches of historical anthropology as a modern philosophy of history allows this discipline to form knowledge about the important mental and cultural foundations of causality, essence and probable prospects of sociocultural dynamics both at the level of “local civilizations” and at the global level. The significance of the analysis of a wide range of psychological and cultural- worldview foundations of socio- cultural processes is explained by the multifaceted and deep nature of their influence on various segments of global social reality, including economic, demographic, scientific- technological, educational, etc.
Потяг, на який ми всі спізнилися: проблеми антропогенезу
Authors: Безродний А. Г.
Published: December 2022

В епоху прискорених соціально-гуманітарних трансформацій (глобалізація, зростання соціальної нерівності тощо) розгляд питання про перспективи розвитку (еволюції) людства набуває підвищеної актуальності, переходить із галузі звичайної світоглядної зацікавленості у сферу «практичної» зацікавленості. Ця стаття є спробою об’єктивної відповіді з позиції синтезу філософського і природничого підходів до проблеми перспектив розвитку людства, з позиції, заснованої на конкретних фактах, а не на «любові до мудрості», яка, як правило, не підкріплена прикладами з галузі реального знання. Важливим для розуміння перспектив людства є уявлення про екологічну нішу, до якої воно адаптоване. Головна властивість екологічних ніш – постійне «вислизання», що призводить до поступового «відставання» біологічних форм умов середовища. Щоправда, є гіперадаптивна стратегія чи нададаптація. Нададаптанти «прагнуть» максимально охопити якісні параметри середовища, тобто, говорячи алегоричною мовою, «обігнати» поїзд еволюції, «зачекати» його на «наступній еволюційній станції». Людство прагне знайти вихід із ситуації, що склалася, в таких напрямах: 1) ми пізнаємо світ і станемо керувати природними процесами; 2) охорона довкілля; 3) використання нових технологій та ресурсів; 4) боротьба із хворобами. Настав час позбавитися утопій типу ноосфер і техносфер. Біологічне середовище (людина) живе за біологічними закономірностями (крім соціальних). Кінець еволюційного тунелю видно, бо ми ще існуємо. Та ось поїзд еволюції вже зник. Одна надія на те, що «ті, хто прийдуть після нас, будуть кращими (мудрішими) за нас».
Role of Jewish joint distribution committee in Ukraine reconstruction in 1920s
Authors: Kryvokon N. I. , Kryvokon O. H.
Published: December 2022

The contribution of American Jewish Joint Distribution Committee and its subsidiary corporation Agro-Joint to the socio-economic development and modernization of Ukraine in the 20s of the 20th century is highlighted. Based on the analysis of historical sources and publications of the Soviet press, it was found that during this period the mentioned organizations played an important role in the socio-economic processes that took place in South of Ukraine and in Crimea. This was connected with overcoming the consequences of the famine, restoration social structure and agriculture, as well as the organization of new Jewish agricultural colonies on allocated lands. The purpose of the study is to clarify the nature of the activities of Joint and Agro-Joint in the 20s of the 20th century in the social sphere and the agricultural sector and to evaluate the results of this activity from the perspective of today. As a result of the research, it was found that the main activity of Joint and Agro-Joint consisted in the organization of large-scale humanitarian, social, technical and agricultural assistance to the inhabitants of Jewish settlements and non-Jewish population of a number of districts in Odesa, Katerynoslav, Donetsk, Volyn provinces and Crimea. At the same time, special attention was paid to the development of associations, the arrangement of life and the supply of equipment, its rational use during agricultural work. It has been found that a public figure, agronomist, and then deputy director of Agro-Joint Samuil Yukhymovich Lyubarskyi (Shmuel-Aba Khaimovich) (1878–1938) played a major role in the organization of charitable and socially oriented aid. Based on the analysis of his article in «Ukrainian Agricultural Gazette» and other works, it was possible to establish hitherto little-known facts from the history of Joint Distribution Committee and Agro-Joint Corporation, which vividly characterize their humanitarian and restorative activities in the specified period.
The contribution of technological institute teachers to the transformation of the architectural space of Kharkiv City
Authors: Gutnyk M. , Tverytnykova O.
Published: December 2022

The article analyzes the transformation processes that took place in the Kharkiv city in the late XIX – early XX centuries. Kharkiv was one of the largest cities in the South of the then Russian Empire. With the beginning of the industrial revolution, the urban environment changed in its facilities and infrastructure. The interaction of city dwellers with the built environment was manifested in the erection of stone townhouses, the opening of the Institute of Technology, a Public Library, and religious buildings, as well as the improvement of life conditions. It was the teachers and graduates of the Institute of Technology who played a leading role in the development of the urban environment. Among the leading architects of that time, it is necessary to single out the achievements of Marian-Jozef- Zdzislaw Charmanskyi, Oleksiy Beketov, Oleksandr Hinzburh, Serhyi Zagoskin, and Mykhailo Lovtsov. If at the end of the XIX century the architectural style of the city of Kharkiv was more of a combination of rationalism, Neo-Renaissance and Neo-Gothic, then from the beginning of the new century the city was built in the Art Nouveau style. It was on the territory of Ukraine that this style had its peculiarities, the so-called Ukrainian Art Nouveau (Modern) appeared. Today, Kharkiv has the largest number of buildings in this style.
Історія та діяльність Українського товариства охорони пам’яток історії та культури на території Харківщини (1966–2021 рр.)
Authors: Ліхолєтов Я. В.
Published: December 2022

Досліджено історію становлення, розвиток пам’яткоохоронної діяльності Харківської обласної організації Українського товариства охорони пам’яток історії та культури, в контексті музейних та пам’яткоохоронних процесів Харківського регіону. У процесі аналізу основних джерел інформації, завдяки яким було розпочато функціонування обласної організації, огляду організаційних операцій становлення, напрямів та форм діяльності, а також взаємодії товариства з державними установами культури, архітектури та мистецтва визначено, що протягом другої половини XX ст. Харківська обласна організація УТОПІК була важливим інструментом у координації та відтворенні пам’яткоохоронної діяльності Харківського регіону, займаючись лекторською, екскурсійною, нормативною та видавничою діяльністю. Впродовж 55 років свого існування, переживаючи злети і падіння, соціально-політичні та економічні перетворення, відсутність фінансів, організація зберегла і створила багато значних для історії об’єктів. Незважаючи на те, що УТОПІК свого часу був ідеологічно заангажований через активність, яка була спрямована на військову історію краю та просвітницьку діяльність, але нині в умовах незалежної України товариство здатне поліпшувати історико-краєзнавчий рух, активізовувати екскурсійно-туристичний кластер, а також бути засновником нових сучасних інформаційних систем у галузі охорони, дослідження та реставрації об’єктів культурної спадщини.
Special features of case marking forms in the first printed New Testament in the Udmurt language
Authors: Bezenova Maria P.
Published: December 2022

Introduction. This article considers the nominal case markers in the first printed New Testament in the Udmurt language. These manuscripts are known as the first sources for studying the process of the case system formation, as well as the morphology of the Udmurt language as a whole.
Materials and Methods. The research was conducted on the basis of the corpus of the texts published in 1847, which comprise Gospels of Matthew and Mark translated in the Glazov and Sarapul dialects of the Udmurt language. The analysis was carried out by comparing the linguistic material of the written sources with the data of the Standard Udmurt language and its dialects.
Results and Discussion. During the study, three main features were identified in the case indicators of monuments: a) formation of accusative plural forms in the simple declension in all sources with the help of the marker -ызъ; b) use of the forms with the initial и in the first books instead of ы-forms in Standard Udmurt in the instrumental, inessive, elative and prolative cases; c) the presence of the marker -энъ in the text of the New Testament in the Sarapul dialect, alongside with the common suffix -ынъ, which serves as the means for building nominal plural forms in the instrumental case. In addition, the manuscripts in the Glazov dialect demonstrate forms of secondary local cases, as well as instances of using egressive forms in the function of elative.
Conclusion. Analysis of the case markers in the first Udmurt New Testament demonstrated special features of different nature, which can be explained by orthography as well as dialectal features of the studied sources.
A written monument of Siberian writing “A brief description of the Ostyak people” by Grigory Novitsky: historical and cultural analysis
Authors: Vykhrystyuk Margarita S.
Published: December 2022

Introduction. The written monument of Siberian writing “A brief description of the Ostyak people” contains a unique description of the life of the indigenous population of Siberia, the Ostyaks, made by a historiographer Grigory Novitsky on the basis of personal observations. The article analyses the structure and content of the monument, presents a historical information about the time of creation and its authorship, notes the historical and cultural significance of the source. The objective of the article is to carry out its historical and cultural analysis, including the analysis of its structure and content.

Materials and Methods. The study was based on the material of the Siberian written monument of the early XVIII century “A brief description of the Ostyak people” by G. Novitsky. To obtain objective conclusionsthe author employed descriptive and comparative methods. When analyzing the structure, content and information value of the text, the methods of component analysis and structural-semantic were used.

Results and Discussion. The article presents the historical and cultural analysis of the first ethnographic work on Siberia. It contains an analysis of the description of the life and culture of the Ostyaks who historically lives in Siberia, the location of their lands and contacts with other peoples. The book is noted to contain reliable information about the history of Siberia, its borders and natural wealth, the indigenous peoples living in this region, the Tatar tribes, their rulers, the initial reign of Khan Kuchum, the foundation of the first towns of Siberia, as well as the conquest of Siberia by Ermak. In detailed way the text shows the area that at that time was inhabited by the Khanty. Historically, the representatives of various language groups lived here. The text of the written monument provides the information about the diversity of cultures and languages on the territory of Siberia. The rich and varied ethno-cultural linguistic material of the written monument witnesses the state of the Russian literary national language in the period of the formation of its norms.

Conclusion. The text of the written monument, containing an extensive description of the Siberian lands and the peoples living there, is a valuable historical and ethno-cultural material for researchers, the evidence of the processes that took place in the Russian language during the formation of its norms.