bluuebunny/crossref_metadata_2025 huggingface dataset:
Measuring Customers Loyalty Through Satisfaction In E-Commerce: An Empirical Study On Tokopedia
Authors: Vania Tanlim  , Setiawan Ruslim Tommy
Published: October 2024

This study aims to empirically examine the impact of e-service quality, e-commerce innovation, utilitarian value, and hedonic value on customer loyalty, with customer satisfaction as a mediating variable at Tokopedia. The research population consists of Tokopedia users in Jakarta. The sample for this study includes 252 participants selected through screening questions and collected online via Google Forms using judgmental sampling. The data is processed using Partial Least Squares Structural Equation Modeling (PLS-SEM). The results indicate a positive and significant influence of e-service quality, e-commerce innovation, utilitarian value, and hedonic value on customer loyalty, both directly and indirectly, through the mediation of customer satisfaction.
Open Innovation And Digital Marketing: A Catalyst For Culinary SMEs In Makassar
Authors: Halik Johannes Baptista , Halik Maria Yessica
Published: October 2024

Through an open innovation process, this study aims to determine the impact of IT awareness and digital marketing on the performance of SMEs in Makassar City. A sample of 94 SMEs using the Lameshow formula was collected in Makassar City for this study. The study shows that in Makassar City, IT awareness and digital marketing have a substantial and beneficial impact on the openness of innovation processes for SMEs. Given the results of this study, it was found that SMEs in Makassar City should start to increase their information technology awareness and use Digital Marketing for Open Innovation processes to improve their performance.
Investigation of Corrosion Inhibition of Carbon Steel by Using Natural Iraqi Plum Tree Gum in a Saline Medium
Authors: Husseini Marwah , Latief Baraa H. , Khudhair Noor Ali , Huseeni Mustafa D , Al-Saadi Farah Aziz
Published: October 2024

In response to the growing interest in green chemistry and the adoption of environmentally friendly and cost-effective compounds in industrial and agricultural applications, this study focuses on exploring the potential of natural compounds. Specifically, the research investigates the corrosion inhibitory properties of Iraqi plum tree gum. The natural gum is characterized using Fourier transform infrared spectroscopy to identify its functional groups and atomic force microscopy (AFM) for further analysis. The electrochemical polarization technique was used to study corrosion measurements for carbon steel (C.S) in saline solution and in the presence of the inhibitor (Plum Tree Gum) in different concentration solutions. The findings revealed a positive correlation between the concentration of plum tree gum and the efficiency of the inhibitor, indicating that higher concentrations of the gum result in increased inhibitory effectiveness.
Human β-Defensin 2 as a Link between EBV Infection and Multiple Sclerosis
Authors: Refaat Aya , Younis Hala
Published: October 2024

Multiple sclerosis (MS) is the result of a complex interaction between environmental factors and genetic predisposition.
 Epstein-Barr virus (EBV) is a significant environmental risk factor associated with MS. Human- beta defensin 2 (HβD-2) is a crucial innate immune response proteint that as an inflammatory marker protects humans from pathogens invading the body like viruses. Therefore, a case-control study was conducted on 90 subjected (48 patients with MS and 42 healthy controls) to examine the role of HβD-2 in EBV viral load infection and MS patients. An enzyme-linked immunosorbentassay kit was used to measure HβD-2 levels in serum. The viral load of EBV was determined using a real-time PCR. The findings revealed that median HβD-2 levels in patients were significantly lower than in controls. (96.62 vs.124.8 ng/mL; p < 0.01). According to the receiver operating characteristic curve analysis, HβD-2 is good predictor for MS disease (area under the curve=0.739; p < 0.001). EBV frequency was lower in MS patients compared to  the controls, although difference was not statistically significant (25 vs. 38.1%; p = 0.181).On other hand, the median (EBV) load was substantially greater in patients than in healthy controls ( 8.55 vs. 1.4 DNA copy/100 cells). This study concluded that HβD-2 levels showed no significant differences in each age group, sex, Expanded Disability Status Scale (EDSS) of multiple sclerosis  patients, rather showed an inverse significant correlation (correlation coefficient = - 0.432) with EBV load, which protect against human viral infections.
Effectiveness of Eucalyptus camaldulensis Leaves Oil in Upregulating exoU expression in Pseudomonas aeruginosa
Authors: Jaddoa Nihad T. M. , AL-Sheikhly Mahmood A. H. , Aldobaissi Israa A.M. , Al-Mathkhury Harith J. F.
Published: October 2024

Results of the current study demonstratedthat out of eighty-three isolatesof Pseudomonas aeruginosa,only twenty-five isolateswere resistant to five different antibiotics (of different classes) that were consequentlyconsideredmultidrug resistant isolates.These isolates developed variable susceptibility toward Eucalyptuscamaldulensisleavesoil (ECO). GC-MS analysis of ECOrevealed that the aromatic oil eugenol is the major constituent.However, the most frequent MIC was 0.39 µg/ml, while the lowest frequent MIC was 3.125 µg/ml.Moreover, this oil at ½ MIC (0.195µg/ml) increased the gene expression of exoU. Itis concluded from the outcomes of the studythat ECOmay cause severe damagewhen used to treat infections caused by P. aeruginosa.
Inhibition of the Hyaluronidase Enzyme Produced by Staphylococcus Bacteria Using Vasicine Alkaloids of the Vasica Plant
Authors: Fayyad Sara Ali , Majeed Majid Rasheed
Published: October 2024

Hyaluronidase is an enzyme that breaks down primarily hyaluronic acid, thereby disrupting the structural integrity of the extracellular matrix (ECM) found in connective tissues, which is considered a virulence factor. The aim of this research was to study the effect of a plant-active compound (vasicine) that was separated from a plant sample as an inhibitor agent for the hyaluronidase enzyme that was isolated from Staphylococcus aureus, which is considered a virulence factor. 120 samples were randomly isolated from infected burns. The isolates showing highly hydrolyzed zones were identified. Cell growth as well as hyaluronidase activity are measured spectrophotometrically by the turbidity reduction assay. The results showed that 100 out of 120 clinical samples grew bacteria when cultured on blood agar medium. Also, it was found that of the 100 isolates, 56 (56%) belonged to S. aureus and had an inhibitory zone of hyaluronidase of 5–26 mm, and the inhibitory zone was increasing over time.
Influence of Forced Field on Blood Flow in an Overlapping Stenosed Arterial Section
Authors: Dhange M. , Sankad G. , Bhajakkanar U. , Jaafar Nurul Aini
Published: October 2024

This article presents the theoretical analysis of the nonlinear behavior of the blood flow through an angled arterial segment with overlapping stenosis. A mathematically created time-variant stenosis emerges from the formation of arterial narrowing brought on by atheroma. An elastic cylindrical tube with a moving wall is used to represent the artery, and the Casson liquid is used to simulate blood that flows through it. The nonlinear elements that arise in the equations, govern blood flow are taken  into account.  The impact of the pulsatile pressure gradient that caused by the regular heartbeat on the flow process in the stenosed artery is demonstrated  mathematically. By employing the boundary conditions, the present analytical technique can easily compute the velocity profiles, wall shear stress, and flow resistivity. To carry out a systematic quantitative study, the desired quantities are numerically computed. The results are graphically presented in the discussion section. They provide an overview of how the degree of stenosis and the malleability of the artery wall influence blood flow abnormalities. The application of the current model is adequately justified by many significant conclusions.
The Degree-Topology of CertainTypes of Graphs and PT0-Space
Authors: Hameed Zainab Naji , Kadhem Hiyam Hassan
Published: October 2024

This work aimed to study the degree topology of certain types of graphs namely, the wheel, helm, gear, pan, tadpole, and windmill graphs, respectively. In addition, a new separation axiom known as -space that joins the topological space and paths in the graph is introduced. Also, the relation between -space and the degree-topology of the connected and disconnected graph was stydied. Moreover, many examples were studied in new separation space.
s-WH Modules
Authors: Mohammed Osama Basim , Ghawi Thaar Younis
Published: October 2024

This article introduces the concept of strongly-WH module which is a proper generalized of Hopfian modules.  A module  is called strongly-WH, briefly -WH if, any -small surjective -endomorphism of  is an automorphism. We specify and provide some properties of this concept. Furthermore, we have established connections between strongly-WH modules and various other concepts. We demonstrate that every strongly-WH module is -weakly Hopfian. As well as, we provide cases in which the concepts of WH, -weakly Hopfian, and strongly-WH modules are equivalent.
On Efficient Method For Fractional-Order Two-Dimensional Navier-Stokes Equations
Authors: Jassim Hassan , Ahmed Hijaz , Hussein Mohammed , Singh Jagdev , Kumar Devendra , Shah Rasool , Zayir Muslim , Cherif Mountassir , Jabbar Kadhim
Published: October 2024

For the solution of fractional-order two-dimensional Navier-Stokes equations (FOTDNSEs), the current work proposes a novel variant of the Laplace Adomian decomposition approach with the Atangana-Baleanu fractional operator in the Caputo sense (ABCFO). In this approach, the solution is considered as a Taylor series expansion that converges rapidly to the exact solution. Only two components are required for the new approximation analytical technique. When compared to other strategies, the current method is very simple, requires less calculation, and is extremely accurate.
Role of Zinc Alpha2-Glycoprotein and Retinol-Binding Protein-4 in Iraqi Women with Thyroid Dysfunctions
Authors: Abd Kawther A. , AL-Qaisi Alaa Hussein J. , Hussein Shaimaa A.
Published: October 2024

Thyroid dysfunction (TD) and diabetes mellitus (DM) are two of the most frequent chronic endocrine disorders. This study included 60 women with thyroid disorders: 30 with hypothyroidism and 30 with hyperthyroidism, aged between 20 and 40 years. This study used 30 healthy women aged 20-40 years as a control group. Anthropometric measurements of Body Mass Index (BMI), hematological analysis of glycated hemoglobin (HbA1c), biochemical parameters (Thyroid-stimulating hormone TSH, Free triiodothyronine FT3, Free thyroxine FT4, Fasting Blood Sugar FBS), and adipokine concentrations zinc-α2-glycoprotein (AZGP-1) and retinol-binding protein-4 (RBP-4) were performed for all participants. The results revealed that the serum levels of zinc-α2-glycoprotein and retinol-binding protein-4 are significantly higher in hyperthyroidism (P<0.0001) compared to both healthy and hypothyroid women. Besides that, zinc-α2-glycoprotein has a negative correlation with TSH in the hyperthyroidism group. In the hypothyroidism group, it correlates positively with retinol-binding protein-4. In addition to that, retinol-binding protein-4 is positively correlated with FT3 and FT4 and negatively correlated with BMI in the hyperthyroidism group. For this reason, we conclude that these adipokines can aid in the diagnosis and monitoring of thyroid disorders, thereby preventing the onset of disease complications associated with type 2 diabetes mellitus. It is important to highlight that women with hypothyroidism are more likely than those with hyperthyroidism to develop diabetes.
The Use of the Carbonyl Group (C-3) of Isatin for the Construction of Pyrazoline Moiety and the Study of its Antioxidant Activity
Authors: Dawood Rafid S. , Faisal Farah N.
Published: October 2024

A series of novel pyrazoline derivatives 5-13 were synthesized in three steps from isatin, with yields ranging from 40 to 72% over the multistep procedure. The first step included the condensation of isatin with p-aminoacetophenone to afford the corresponding Schiff base 1 in a 75% yield. In the second step, the enolate form of Schiff base 1 was reacted with different aromatic aldehydes (benzaldehyde, p-nitrobenzaldehyde, and p-chlorobenzaldehyde) to give the title chalcone derivatives 2-4 in 60-72 yields. In the third step, pyrazoline derivatives 5-13 were synthesized via cycloaddition reactions between compounds 2-4 and hydrazine hydrate, phenyl hydrazine, or p-nitrophenyl hydrazine. The cycloaddition produced the target pyrazoline compounds in 40-72% isolated yields. All prepared compounds were characterized by FT-IR and 1H NMR spectroscopy. Some of the prepared compounds were tested for antioxidant properties.
Current Prevention and Clinical Management of COVID-19 in India
Authors: Shanmugam Dharani Abirama Sundari , Choudhury Rishi , JAVN SB , Ganesan Vinoth Kumar , Malngiang Magrita , Sakthivel Meenakumari , Kar Abhijit , Franco Abishek , Kumar Merugumolu Vijay
Published: October 2024

The COVID-19 pandemic has clasped the world by furore storm. India has been the epicenter of the surge in COVID cases since March 2021 which is being considered as the second wave. With every passing week, new guidelines were being implemented by various states as well as the central government to control the situation. Hospitals were running out of beds, oxygen, and medicinal supply with patients with comorbidities suffering the most. A handful of drugs have been approved for direct or emergency use to counter the situation. However, over time some of these drugs have faced strong backlash for being ineffective and hence are no longer in use. In this review, we shall study various vaccines that have been approved in India and abroad and, also various drugs which were approved for treating the COVID-19 patients.
Evaluation of Some Immunological and DNA Damage Parameters among Patients with Rheumatoid Arthritis
Authors: Salman Shams A. , AL-Jumaily Rakad M. Kh
Published: October 2024

Rheumatoid arthritis (RA) can cause permanent joint damage and disability through inflammation in the joints. Other organs, such as blood vessels, lungs, heart, eyes and skin may also get affected. This study aimed to evaluate the changes of some oxidative stress markers including oxidative DNA damage and the clinical outcomes that are associated with Iraqi rheumatoid arthritis patients. Commercial enzyme linked immunosorbent assay (ELISA) kits were applied to evaluate malondialdehyde (MDA), DNA damage marker 8-hydroxy-2-deoxyguanosine (8-OHDG), and glutathione peroxidase 3 (GPX3) levels in serum of 60 patients having RA with ages ranging between 20-70 years and 30 age-matched healthy controls. The results showed a significant increase in MDA levels in RA patients compared with the control group. Also, the levels of GPX3 decreased in RA patients with highly significant differences as compared with healthy control. Highly significant serum levels of oxidative DNA damage in RA patients were observed compared to the control group. Body Mass Index (BMI) results indicted significant differences between RA patients and healthy control. It can, therefore, be concluded that there is a potential role if malondialdehyde, oxidative DNA damage and GPX3 are used as biomarkers for progression of in patients with RA.
INTERSECTING MEDICAL AND LEGAL RESPONSIBILITIES IN INDONESIA
Authors: Komalasari Rita , Mustafa Cecep
Published: October 2024

The primary objective of this research is to illuminate the evolution of medical responsibility in Indonesia over time. By examining the complex interplay between law and medicine, social transformations, medical advancements, and shifting legal perspectives, this study seeks to enhance understanding of medical responsibility in Indonesia. Utilizing an interdisciplinary approach grounded in the "Social Construction of Technology" (SCOT) theory, the research employs historical analysis to trace the origins of medical responsibility, its evolution, and the impact of various legal frameworks and cultural shifts in medicine. The study integrates qualitative data from legal and medical sources to provide a comprehensive view. Findings reveal that the evolution of medical responsibility in Indonesia is closely tied to the adoption of, and subsequent resistance to, entrenched notions within medical discourse. The research identifies a trend towards greater judicial independence from traditional medical narratives and an increased willingness to scrutinize established medical practices, particularly in the context of technological advancements. By situating these developments within Indonesia's historical and cultural context, this research enriches the understanding of medical liability's progression and ongoing transformation within a dynamic healthcare landscape. It addresses gaps in existing literature and offers a nuanced perspective on the interaction between law and medicine concerning medical liability.
Consideraciones dialectológicas sobre expresiones para dar agradecimiento y su inclusión en la enseñanza-aprendizaje del ELA
Authors: Caro Martínez Daniela , Zuluaga Molina Juan Felipe
Published: October 2024

En el Valle de Aburrá no sólo se dice “gracias”, se dice “mi Dios se lo ha de multiplicar”, “sos un sol” o “la buena”. Como se observa, la cultura y la realidad social de los hablantes también se reflejan en sus formas de agradecer. Por lo anterior, esta investigación cualitativa buscó identificar las expresiones para dar agradecimiento (EXPADA) del español estándar y de la variante paisa, así como también comprender cuál ha sido el tratamiento que se les ha dado en la enseñanza de español como lengua adicional (ELA). Del trabajo, se concluye que es necesario enseñar e integrar las EXPADA desde las primeras etapas de adquisición del español y a través de los distintos niveles, procurando un balance entre su complejidad, inclusión curricular y registro respecto al nivel.
Reseña del libro “Atane nos enseña. Español como segunda lengua para niños Eperãarã Siapidaarã. Nivel básico”
Authors: Nieto Martín Gloria Viviana
Published: October 2024

Atane nos enseña. Español como segunda lengua para niños Eperãarã Siapidaarã. Nivel básico es la propuesta ganadora de la Beca Instituto Caro y Cuervo de Creación de materiales didácticos para la enseñanza de español como lengua extranjera y segunda lengua, de la Convocatoria Nacional de Estímulos 2023 del Ministerio de las Culturas. Si bien corresponde a la publicación número doce de la serie ELE/2 del Instituto Caro y Cuervo (ICC), se trata del primer manual de la serie dirigido a la enseñanza de español como segunda lengua a una comunidad indígena específica. Más aun, se trata del primer material didáctico que supera los formatos limitados de guía, unidad o cartilla que suelen crearse para las comunidades indígenas.
Internal Electrostatic Discharge Modeling: Validation and Fitting Using Tests on Insulated Wires
Authors: Chinn James , Kim Wousik , Andersen Allen , Thorbourn Dennis , Martin Eduardo
Published: October 2024

Electron beam tests were conducted to observe the internal electrostatic discharge behavior of four wire samples arcing into three termination resistors. The charging environment during the test was also simulated using 3-D NUMIT to calculate the expected voltage development within each wire. The impedances of the wires and the test setup were measured and included in a circuit model of the discharging wire connected to the measurement circuit. The circuit model was fit to the largest discharge observed on a 50 Ω load. The circuit model was then used to simulate discharges into 5 kΩ and 10 MΩ terminations, and the simulated pulses were compared to observed pulses on those terminations. Simulated peak voltages agree with observed voltages to within a factor of 1.6 and simulated decay times agree with observed decay times to within a factor of 2.3. For large pulses, derived source voltages range from 3.7 to 15.5 kV, derived source capacitances range from 4 to 11 pF, and derived source resistances range from 1100 to 3500 Ω.
Gain-Based Feedback for Shape Control of Antenna Reflectors Using Deep Q-Network Algorithm
Authors: Zhang Zehua , Chu Weimeng , Ma Qingnan , Song Xiangshuai , Liu Dakai , Wu Xiande
Published: October 2024

An intelligent shape control method for antenna reflectors is proposed using gain feedback instead of displacement feedback, considering the limitations of high-precision deformation measurement on orbit. Moreover, the finite element method is used to establish an analysis model of a grid reflector with embedded piezoelectric actuators, and the antenna gain formula is derived. To solve the multidimensional control laws from a single gain dimension, an active shape control model training framework is proposed based on the deep Q-network algorithm, including the state space, action space, and reward function. Numerical simulations, with errors stemming from two typical thermal loads as the initial errors, are conducted to illustrate the effect of the proposed control method. The influence of the voltage step size on the shape control precision is analyzed, and further online training is discussed for implementing control. The results indicate that the proposed method reduces the root-mean-square (RMS) error by more than 50% The control effect of the trained control model on other error conditions does not perform as desired. However, online training can effectively solve this problem, achieving faster convergence and a significant reduction of the RMS error.
Mixing Enhancement Mechanism of Liquid Jet in Supersonic Crossflow with Gas Throttling
Authors: Zhou Yaozhi , Cai Zun , Li Qinglian , Li Fei , Yang Xiaolong , Wang Taiyu , Li Chenyang , Wei Feng , Chen Zihang , Sun Mingbo
Published: October 2024

Numerical and experimental studies were conducted to uncover the physical aspects of a liquid jet injected into a supersonic crossflow with gas throttling systematically. The results were obtained with the inflow conditions of a Mach number of 2.0, a total temperature of 300 K, and a total pressure of 0.55 MPa. The results show that fuel–air mixing is considerably enhanced due to shock-induced flow distortion by adding gas throttling. The strength of downstream backpressure determines the distance of forward movement of the throttling shock wave train and the flowfield structure in the channel. When the mass flux of gas throttling is high, the influence of throttling gas spreads across the expansion section, resulting in significant flow separation in front of the liquid jet. It is found that the spray flashback phenomenon is similar to the flame flashback phenomenon that occurs in the supersonic combustion process under the action of a precombustion shock train. The wall counterrotating vortex pair and induced cavity streamwise vortices are enhanced with the increase of the flux of gas throttling. The relatively high-pressure environment generated by gas throttling promotes the atomization of droplets. As a result, the mixing enhancement mechanism of a liquid jet in a supersonic crossflow with gas throttling is mainly due to the combined effects of 1) the shock waves separating the side wall boundary layer and modifying the local flow state of air in the combustor, which lead to a dramatic increase in fuel–air mixing, and 2) the streamwise vorticity values as well as the residence time resulting from channel blockage elevating.
Ansiedade e estresse como fatores que afetam o desempenho academico dos estudantes de enfermagem do centro universitario de Caratinga
Authors: Silveira Rafaela Benevenuto Freitas da , Magalhaes Ednalva Firmino , Guerra Carlos Henrique Wernersbach , Soares Ana Cristina Rodrigues , Arcanjo Bruna Luiza Ferreira , Silveira Isabela Benevenuto Freitas da , Arruda Jacqueline Souza Dutra , Silva Pamela Maria Vieira da , Ferreira Vitória Cristina tavares da Sales , Silvério Viviane Aparecida
Published: October 2024

Objetivo: Avaliar a ansiedade e o estresse como fatores críticos que afetam o desempenho acadêmico dos estudantes de enfermagem em uma universidade do interior de Minas Gerais. Métodos: Realizou-se um estudo observacional, transversal e descritivo com abordagem qualitativa. Utilizou-se um questionário online com perguntas sobre alterações na ansiedade, tratamento psicológico, nível de estresse, causas de estresse e habilidade de lidar com situações estressantes. A amostra incluiu 26 alunos, e a análise dos dados foi qualitativa, identificando padrões e tendências. Resultados: Dos alunos, 61,54% desenvolveram ansiedade após ingressarem na faculdade. A maioria (65,38%) não busca tratamento psicológico, e 42,31% se classificam como muito estressados ​​diariamente. As principais causas de estresse são questões de estudo. Estratégias de enfrentamento incluem atividades relacionadas ao sono, exercícios físicos e compartilhamento de emoções. Conclusão: Os resultados evidenciam a prevalência de ansiedade e estresse entre os estudantes de enfermagem, destacando a necessidade de intervenções institucionais. As sugestões dos alunos, como promoção de lazer, apoio institucional e divulgação de serviços de terapia, oferecem insights para políticas que promovam um ambiente acadêmico saudável. A compreensão dessas questões é crucial para o desenvolvimento de estratégias que capacitem os estudantes a enfrentar os desafios da formação profissional.
Situação epidemiológica de mulheres vítimas de violência doméstica em Anápolis/GO entre os anos de 2021 e 2022
Authors: Oliveira Anna Laura Silva , Vaz Matheus Hernandes Vieira , Almeida Gabriella Maria de , Adorno Ana Luísa Vasconcelos de Pina , Barbosa Ana Laura Pereira , Silva Constanza Thaise Xavier , Silvestre Marcela de Andrade
Published: October 2024

Objetivo: Descrever a situação epidemiológica de mulheres vítimas de violência doméstica conforme boletins de ocorrência registrados em Anápolis/GO entre os anos de 2021 e 2022. Métodos: Trata-se de um estudo transversal quantitativo, conduzido através de investigação de boletins de ocorrência da Delegacia Especializada no Atendimento à Mulher (DEAM) de Anápolis/GO, alcançando cerca de 2.088 inquéritos, com análise de agressão, características sociodemográficas das vítimas e gênero do agressor. Foram considerados: meio e tipo de agressão e idade e cor das vítimas. Foi utilizada planilha eletrônica do programa Microsoft Office Excel 2021. O estudo foi aprovado por Comitê de Ética em Pesquisa. Resultados: Percebeu-se um aumento geral e significativo das denúncias feitas no decorrer dos anos estudados: 33,22% sobre lesões corporais; 21,9% sobre ameaças; 72,6% em relação ao estupro. Foi possível identificar também o aumento do número de casos cuja cor da vítima não foi informada. Conclusão: O trabalho realizado demonstra aumento substancial dos casos de ameaça, lesão corporal e números ínfimos de estupros e feminicídios. Observou-se uma discreta divergência no perfil epidemiológico das vítimas e sua apresentação nos boletins em comparação com balanços nacionais.
Evidências científicas sobre políticas públicas para pessoas idosas no Brasil
Authors: Moretto Isabela Vitória , Marques Izabelly Simeão , Marques Alethia da Silva , Ribeiro Esdras de Souza , Camargo Izabelly Rubio do Amaral , Lima Jasminy Roberta Fortunato , Tashima Cristiano Massao , Katakura Edna Aparecida Lopes Bezerra , Alarcon Miriam Fernanda Sanches
Published: October 2024

Objetivo: Identificar nas produções nacionais, as evidências acerca das Políticas Públicas para pessoas idosas no Brasil. Métodos: Trata-se de uma revisão integrativa, empregando-se a estratégia PICO, descrita da seguinte forma: P: pessoa idosa no Brasil; I: políticas públicas; C: ausência de políticas públicas; O: evidências científicas que embasam as políticas públicas. Como questão norteadora, utilizou-se: Quais são as evidências científicas que embasam as políticas públicas voltadas para a população idosa no Brasil? Resultados: A busca dos estudos ocorreu de novembro de 2022 a abril de 2023 e contou com os seguintes descritores: "Pessoa Idosa", "Aged", "Envelhecimento", "Aging", "Participação Cidadã", "Community Participation", "Políticas Públicas", "Public Policy". As bases de dados utilizadas foram a Biblioteca Virtual em Saúde (BVS) e SciVerse Scopus. Os critérios de inclusão foram trabalhos referentes à temática acerca das Políticas Públicas para pessoas idosas no Brasil, considerando no levantamento bibliográfico sem tempo limite de publicação e artigos disponíveis na íntegra, além de decretos, leis, portarias e resoluções no idioma em português. Foram excluídas monografias, dissertações, teses e excluídos os artigos duplicados. Considerações finais: As evidências científicas ressaltam a necessidade premente de políticas públicas eficazes, que garantam acesso à saúde, segurança e promovam a participação ativa dos idosos na sociedade.
Assistência de enfermagem às mulheres mastectomizadas: principais aspectos das dimensões física, psicológica e espiritual
Authors: Rodrigues Sarah Regina Gonçalves , Ferreira Maria das Graças Nogueira , Pessoa Juliana dos Santos , Silva Glaydes Nely Sousa da , Silva Amanda Benício da , Santos Anderson Felix dos , Trigueiro Débora Raquel Soares Guedes
Published: October 2024

Objetivo: identificar aspectos das dimensões física, psicológica e espiritual considerados na assistência, a partir de evidências científicas encontradas. Métodos: Trata-se de uma Revisão Integrativa da Literatura desenvolvida a partir de buscas no portal de periódicos da Capes e Pubmed, considerando manuscritos publicados entre 2016 e 2021. A partir da utilização dos critérios de elegibilidade, foram incluídos 17 artigos. Resultados: Registrou-se na dimensão física a percepção da mutilação e da perda de cabelo como fatores de alteração da autoimagem. Sendo uma doença com elevado estigma social, evidenciou-se na dimensão psicológica uma expressiva menção à sintomas referentes ao processo de adoecimento mental. Na dimensão espiritual, identificou-se a fé como terapia não farmacológica para o enfrentamento da doença. Consideraçãos finais: O tratamento do câncer de mama pode modifica a imagem corporal das mulheres e resulta em angústia, medo e estresse. Dessa forma, considerar fatores psicoespirituais, além dos físicos tem grande valia na definição de eixos assistenciais que atendam a integralidade da pessoa.
Eficácia de infiltrações intra-articulares guiadas por ultrassom no tratamento da dor em pacientes com Osteoartrite do Joelho
Authors: Santana Bruno Sousa , Oliveira Larissa Alencar de , Xavier Rodson Melo , Tannus Lorena de Oliveira , Feitosa Marcela de Oliveira
Published: October 2024

Objetivo: Realizar revisão integrativa sobre a eficácia de infiltrações intra-articulares guiadas por ultrassom no tratamento da dor em pacientes com osteoartrite do joelho. Métodos: Trata-se de um estudo do tipo revisão integrativa. A amostra foi composta por trabalhos científicos que responderam à questão de pesquisa e a coleta de dados realizada em fevereiro de 2024. Resultados: Constatou-se que o tratamento oral para OAJ não é suficiente para controlar a doença e, por essa razão, a prescrição de infiltração por via intra-articular tem sido satisfatória, principalmente quando guiadas por ultrassom. As infiltrações melhoram a rigidez, a capacidade funcional e a mobilidade. Além disso, proporcionam maior conforto, bem-estar e qualidade de vida para o indivíduo com OAJ.  Conclusão: as infiltrações intra-articulares guiadas por ultrassom são mais eficientes que outras modalidades farmacológicas, por reduzirem significativamente as queixas álgicas em período mais prolongado, melhorar a rigidez, capacidade funcional, mobilidade e por assegurar aos portadores de OAJ maior conforto, bem-estar e qualidade de vida. Além disso, as infiltrações intra-articulares guiadas por ultrassom são realizadas de forma mais segura e eficaz.
Unveiling the hidden culprit: How the brain-gut axis fuels neuroinflammation in ischemic stroke
Authors: Ma Brian D. Y. , Chan Travis Y. H. , Lo Benjamin W. Y.
Published: October 2024

Background:

The brain-gut axis represents a bidirectional communication network between the gut microbiome and the central nervous system that plays an important role in homeostasis. Compelling evidence now confirms that ischemic stroke disrupts this delicate balance by inducing gut dysbiosis.

Methods:

A comprehensive literature search was performed in PubMed, Web of Science, and Google Scholar for articles published between January 2000 and January 2023 using relevant keywords. Studies were limited to English and included original studies, literature, and systematic reviewers from peer-reviewed journals which discussed gut microbiota composition in models/subjects with ischemic stroke or assessed stroke impact on gut microbiota. Comments, meeting abstracts, and case reports were excluded. From the 80 relevant articles, we summarized key findings related to gut microbiota changes after stroke and their association with stroke outcomes.

Results:

Emerging preclinical evidence underscores the pivotal role of the gut microbiome in glial cell development and function. Germ-free models exhibit compromised microglial activation and impaired cellular debris clearance, exacerbating tissue damage following ischemic stroke. Targeted interventions, including prebiotics, probiotics, and fecal microbiota transplantation, have demonstrated efficacy in rescuing glial phenotypes in preclinical stroke models. Beyond its local effects, the gut microbiome significantly influences systemic immunity. Ischemic stroke polarizes pro-inflammatory phenotypes of neutrophils and T cells, amplifying neurovascular inflammation. Microbiota manipulation modulates leukocyte trafficking and metabolic signaling, offering potential avenues to mitigate infarct pathology.

Conclusion:

Our review demonstrates that in preclinical stroke models, modulating the lipopolysaccharide, short-chain fatty acid, and trimethylamine N-oxide pathways through the gut-brain axis reduces infarct sizes and edema and improves functional recovery after ischemic stroke. Further exploration of this important axis may unveil additional adjunctive stroke therapies by elucidating the complex interplay between the microbiome and the brain. Rigorously controlled clinical studies are now warranted to translate these promising preclinical findings and investigate whether manipulating the microbiome-brain relationship can help improve outcomes for stroke patients. Overall, continued research on the gut-brain axis holds exciting possibilities for developing novel treatment strategies that may enhance recovery after stroke.
Neurocircle microsurgery model: Description of simulation-based training and exoscope
Authors: Yataco-Wilcas Christian Alexander , Lengua-Vega Luis Alberto , Coasaca-Tito Yosimar Salomon , Diaz-Llanes Bruno Eduardo , Salazar-Campos Cristian Eugenio
Published: October 2024

Background:

Microsurgery is crucial in neurosurgery, requiring precise skills for interventions on delicate structures. Effective training is essential for developing these skills. In Peru and Latin America, however, there is a notable shortage of specialized training centers and high costs associated with foreign simulators, hindering the development of neurosurgical skills. To address this issue, the NeuroZone3D Research Center has initiated a project to create a national dataset on Peruvian craniometry and develop locally adapted training models.

Methods:

The “NeuroCircle Microsurgery Model” was created through a multi-phase process. Phase 1 involved designing a simulation platform using a 3D printer. Phase 2 focused on creating a realistic biomodel with polyurethane and advanced modeling techniques. In Phase 3, the biomodel was assembled and integrated into the platform. Phase 4 included using a wooden module, a cost-effective exoscope simulation, and surgical instruments to provide a realistic training environment.

Results:

The “NeuroCircle Microsurgery Model” provided a stable and effective training environment. Feedback from training sessions with neurosurgery residents and medical students indicated significant improvements in microsurgical skills. Participants valued the model’s realism and its role in enhancing their surgical proficiency.

Conclusion:

The “NeuroCircle Microsurgery Model” is a significant advancement in microsurgery training for Peru and Latin America. Its development provides a valuable, locally adaptable tool for improving surgical skills and addresses the critical training gaps in the region.
Muhammadiyah and Nahdlatul Ulama: The Spirit of Transformative and Character Education in Jeddah Indonesian Schools
Authors: Purnomo Halim
Published: October 2024

Penelitian ini bertujuan untuk menjelaskan bahwa Muhammadiyah dan Nahdlatul Ulama memiliki peran penting dalam mewarnai proses pendidikan transformative dan Pendidikan karakter di sekolah Indonesia Jeddah. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi etnografi. Pengumpulan data dilakukan dengan wawancara dan analisis dokumen. Teknik analisis data digunakan untuk mendeskripsikan data hasil wawancara, mengadopsi berbagai pemikiran pendiri dan tokoh, menganalisis dokumen kurikulum dan profil sekolah serta melanjutkan penyajian data yang disusun dalam bentuk laporan penelitian. Penelitian ini mejelaskan bahwa semua pihak yang tertarik dengan dunia pendidikan di Indonesia, baik yang diselenggarakan di dalam negeri maupun di luar negeri, khususnya di Sekolah Indonesia Jeddah terus memberikan kontribusi terutama oleh Muhammdiyah dan Nahdatul Ulama. Membangun pendidikan transformatif dan pendidikan karakter bagi Muhammadiyah dengan Slogan Islam Berkemajuan melalui semangat mengadaptasi dan mengintegrasikan dikotomi holistik ilmu pengetahuan yang menerapkan nilai-nilai humanisasi, pembebasan, dan transendensi serta internalisasi dalam Ali Imran ayat 104 dan 110 yang menginspirasi lahirnya Muhammadiyah. Islam Nusantara sebagai slogan Nadhlatul Ulama berkontribusi pada akulturasi masyarakat Indonesia yang plural dengan berbagai tradisi, sehingga nilai keragaman tetap terjaga di tengah arus globalisasi. Dua slogan keislaman dari dua organisasi Islam terbesar di Indonesia telah berkontribusi nyata menguatkan soft skill siswa menyiapkan masa depannya dengan penguatan nilai-nilia budaya keindonesiaan sebagai tempat kelahirannya.
Tetraperoxotitanates for High Capacity Direct Air Capture of Carbon Dioxide
Authors: Bach Karlie , Garrido Ribo Eduard , Hirschi Jacob , Mao Zhiwei , Nord Makenzie , Zakharov Lev , Goulas Konstantinos , Zuehlsdorff Tim , Nyman May
Published: October 2024

Materials chemists play a strategic role towards achieving ambitious global climate goals, including removing legacy CO2 via direct air capture (DAC). Innovating diverse DAC materials will enable their effective use in varying conditions, and bring forth a better understanding of CO2 capture mechanisms. In our current contribution, we have synthesized a family of homoleptic alkali tetraperoxotitanate materials (generally formulated A4Ti(O2)4, A=Li, Na, K) and studied their DAC reactivity. Synthesis was achieved with inexpensive reagents, and >90% yields. We present the first single-crystal X-ray structures (five total) of A4Ti(O2)4 compounds, along with supplemental bulk characterization and computation. We compare their DAC behavior in simple ambient benchtop experiments, determining CO2 uptake by combustion analysis of post-capture materials. The K-analogue exhibited the most rapid and high capacity DAC, 8.17 mmol CO2/gram sorbent, translating to nearly 3 moles CO2 per mole Ti, and reaching near maximum capacity in under 10 days. The Li and Na analogues both exhibit delayed reactivity, but also with high DAC capacity (respectively 6.66 and 8.18 mmol CO2/gram sorbent). Characterization of the DAC products via scanning electron microscopy shows phase separation of alkali-rich and Ti-rich regions in core-shell morphologies for the Na and Li analogues, and this is discussed with respect to the role of the titanium vs the alkali in DAC. On the other hand, no phase separation was observed for the K-analogue. In situ monitoring detailed the early-stage CO2 capture behavior of the K-analogue, and it reaches ~50% of maximum capacity within one hour. The differentiating behavior of the K-analogue is attributed to its unique composition, containing four H2O2 lattice molecules in addition to the four O2- peroxide anions bonded to TiIV. While H2O2 (aq) alone does not exhibit CO2 chemisorption, the basic environment of the A4Ti(O2)4 lattice activates its rapid DAC, inspiring future exploration of peroxosolvate materials for DAC.
Riddles of Vedānta and the Revival of Kotta Satchidananda Murty
Authors: Rajan
Published: October 2024

What is the central philosophy of the Upanishads? Is it theistic, monistic, polytheistic, panpsychistic, or something else? Are the world and God real or unreal? Such questions have been a riddle for ancient sages and modern scholars of the Vedāntic tradition, alike. Interestingly, if any thinker has made this discourse more puzzling, it is none other than Śaṅkarācārya (c. 7th–9th centuries CE); through his famous dictum, Brahma satyam jagat-mithya jivo brahmaiva naparah (“Brahman alone is real, the world is unreal. Jiva is not other than Brahman”), he almost changed the entire Vedāntic paradigm, akin to Nietzsche in Western thought with his “God is Dead” dictum. Now, before any thinker embarks on the Vedāntic path, they must first encounter Śaṅkarācārya’s thesis in one way or another, as only then can one engage with notions including ethics, aesthetics, bhakti, karma, and others. Following the same line of inquiry, this review article investigates Professor K. Satchidananda Murty’s distinctive discourse on Vedānta and his engagement with Śaṅkarācārya’s philosophy, as portrayed in a recent edition of some of his works, titled Vedānta and Bhagavadgītā: The Unpublished Writings of K. Satchidananda Murty, proficiently compiled by Professor Ashok Vohra and Kotta Ramesh.
The impact on NZ university academic staffing over the pandemic years
Authors: Lee Kate , Ben-Tal Alona
Published: October 2024

The New Zealand Association of Scientists (NZAS) sought information from all eight New Zealand (NZ) universities via Official Information Act (OIA) requests. The requests were for academic staff numbers on 1st May 2019 and 1st May 2023, capturing data before and after Covid-19 lockdowns. We requested numbers for permanent, fixed-term and casual academic staff for each faculty onthose dates with a breakdown of men, women and gender unknown/diverse. The aim was to look for impacts over this period on staff numbers in the sciences and how staff in different types of employment and gender were affected, but we also compared this data to other subject areas taught and researched at NZ universities.
Since May 2023 there have been several additional tranches of layoffs at multiple universities which will not be captured in the data we present here. However, while it is arguable whether these new layoffs are due to the impacts of the COVID19 pandemic and subsequent global financial turmoil, we can see that certain subject areas ofacademia have already felt the effects in May 2023. Health faculties fared the best over the period, which might reflect the need for health research and development of the health workforce during a global pandemic. However, these gains were accompanied by large losses in humanities, education, and arts, as well as other subject areas such as fundamental sciences and engineering.
Exploration of Blended Teaching in Financial Management Major of Higher Education Institutions in the Digital Age
Authors: Wang Jue , Ma Xiaoji
Published: October 2024

With the advent of the digital age, universities are starting to break traditional teaching concepts, integrate innovative thinking into teaching models, and strive to improve the effectiveness and applicability of their majors. In order to improve students’ practical ability and employment competitiveness, universities should introduce blended learning methods in classroom teaching, continuously strengthen students’ theoretical knowledge and practical ability, guide them to use the knowledge they have learned to solve practical problems, and enhance their comprehensive strength. This article will analyze the necessity and problems of implementing blended learning in financial management majors in universities, explore the specific path of blended learning in financial management majors in the digital age, and provide reference opinions for universities to cultivate high-quality talents.
Research on Vocational Education Reform and Innovation Based on Information Technology Practice
Authors: Wu Jingting
Published: October 2024

Based on the perspective of information technology reform, higher requirements have been put forward for student management and course teaching in vocational colleges. Therefore, teachers should actively explore suitable opportunities and practical paths to introduce information technology and rely on advanced technology, equipment, and software to promote the reform and development of virtualization, datafication, and intelligence in course teaching. Due to the limitations and influences of various practical factors, teachers face many problems in the application of information technology, which to some extent hinder classroom teaching reform and innovation. Given this, this article discusses the application of information technology, which plays an important role in classroom teaching reform and student ability improvement. This study will briefly explain the concept and characteristics of information technology, analyze the existing problems in current information technology teaching, and finally propose specific reform and innovation practice paths.
Research on the Integration of Ideological and Political Education and Mental Health Education in Undergraduate Colleges
Authors: Wu Fengxia
Published: October 2024

In recent years, the integration research of ideological and political education and mental health education in undergraduate colleges has attracted much attention. The integration of the two can not only help to improve students’ ideological and political quality but also effectively promote the overall development of student’s mental health. With the rapid development and change of society, college students are facing increasingly complex psychological pressure and challenges, therefore, ideological and political education and mental health education combined, have become one of the important directions of the current higher education reform. Based on this, based on a comprehensive analysis of the close relationship between ideological and political education and mental health education, the article takes undergraduate colleges as the research object and actively explores the integration path of the two.
Analysis and Research on the Effectiveness of Computer Teaching in Colleges and Universities
Authors: Dou Qisheng
Published: October 2024

With the deepening of curriculum reform, computer courses are becoming more and more important in the higher education system. To improve the effectiveness of computer teaching has become a topic of particular concern to many educators. This paper aims to build an efficient computer classroom, based on the current situation of computer teaching, summarizes and puts forward many strategies and suggestions to improve the effectiveness of computer teaching in colleges and universities, to provide a new idea and perspective for the reform and innovation of computer teaching, and promote the high-quality development of the overall computer teaching in colleges and universities.