bluuebunny/crossref_metadata_2025 huggingface dataset:
THE CONCEPT OF THE HISTORY OF ANCIENT UKRAINIAN ART IN THE CONTEXT OF DEVELOPMENT ARCHAEOLOGICAL SCIENCE LATE XIX - EARLY XX CENTURY
Authors: Udris I.
Published: May 2022

Becoming of conception of history of ancient Kiev's art in the context of elaboration of archaeological science at end of the XIX and beginning of the XX century. In the article is explained the problem of becoming of scientific conception of history of domestic art. The publications are examined on the indicated problem of leading specialists of that epoch in Labours o f archaeological conventions at end of the XIX and beginning of the XX century as an information base for explaining of historiogyraphy questions in researches of different aspects of history o f the Ukrainian art.
QUALITY OF SELF-ORGANIZATION AS DETERMINING CONSTITUENT OF MAN OF MODEM SOCIAL STRUCTURE
Authors: Udris N.
Published: May 2022

In the article attention is accented to that modem social structure of active transformations requires certain organizational qualities from the actors of different social roles. Existence of such qualities is the condition of support by personality of itself in a viable form in the negative terms of social cha nges and, in addition are realization of the abilities in new social projects. An author briefly opens up essence of these organizational qualities of personality and the necessity of their forming already today at teenagers by the changes in general middle and in out-of-school education becomes firmly established.
Conscientiousness and English Language Performance amidst the COVID-19 Pandemic: Mediation of Self-regulated Learning
Authors: Bourrouk Khalid
Published: May 2022

Conscientiousness and self-regulated learning have been shown to directly impact students’ academic performance; however, whether or not such impact persists in the COVID-19 pandemic era requires further examination. Thus, this study aimed to investigate the association between conscientiousness, self-regulated learning and students' English language performance and examine the mediating effect of self-regulated learning in the relationship between conscientiousness and English language performance during the COVID-19 pandemic. By employing non-probability snowball sampling, 138 first and second-year undergraduate students enrolled at the University of Sidi Mohamed Ben Abdellah, Fez, Morocco, participated in the study by completing a 21-item questionnaire. Using linear regression, the study found a statistically significant relationship between conscientiousness and self-regulated learning [F (1, 136) = 77.41, p < .001, R2 = .37]. Next, a multiple regression analysis was conducted and revealed that while self-regulated learning significantly predicted English language final grades (β = .41, p < .001), conscientiousness was not a significant predictor (β = .14, p > .001). A Sobel test was performed and showed that self-regulated learning was able to mediate the relationship between conscientiousness and English language grades (p < .001). The study concludes that although conscientious students are driven by their diligent work habits, those who lacked effective self-regulated learning strategies received lower grades in their English language class. Hence, educators must concentrate much of their efforts on helping students develop efficient self-instruction, self-monitoring, and self-evaluation techniques that can propel learners into achieving their academic goals.
Enhancing EFL Prospective Teachers' Classroom Management Skills Through the implementation of Flipped Classroom
Authors: Ramadan Israa
Published: May 2022

Numerous endeavours have been detected to improve new techniques, strategies, and methods for enhancing teachers' classroom management skills, both in the pre-service and in-service settings. This study aimed at investigating the effectiveness of using the flipped classroom model in developing Egyptian EFL prospective teachers' classroom management skills. This study adopted the experimental research design that has been exploited in the current study. The sample of the study consists of 34 EFL prospective teachers in Hurghada Faculty of Education, South Valley University, Egypt. The researcher has designed and validated a classroom management questionnaire to be used for data collection purposes. There are statistically significant differences in the mean scores of the experimental and control groups' in providing an atmosphere of classroom discipline in favor of the experimental group in the post-testing in providing an atmosphere of classroom discipline (Mexperimental = 60.88, Mcontrol = 46.29), Stirring pupils' motivation to learn (Mexperimental = 62.94, Mcontrol = 47.58), Regulating the process of classroom interaction (Mexperimental = 71.64, Mcontrol = 55.17), classroom management skills (Mexperimental = 195.47, Mcontrol = 149.06). Therefore, the present study highlighted that the flipped classroom model had a significant effect on developing some classroom management skills of Egyptian EFL prospective teachers. It is recommended that more research is needed to test flipped classroom teaching models for language skills such as listening, speaking, reading, writing, vocabulary, and grammar.
CONCEPTUAL WORLDVIEW IN THE WORKS OF UKRAINIAN WRITERS: THE RENAISSANCE CREATIVITY
Authors: Slipushko Oksana , Zadorozhna Olena , Gayevska Olena , Lisovska Olha , Katyuzhynska Anastasiya
Published: May 2022

This study explores the peculiar features of the conceptual worldview of Ukrainian writers active during the Renaissance (late 15th-16th centuries). Its ultimate goal resides in analyzing the most common interpretations of the concepts of history, state, freedom, ruler, and war by authors working on the territory of Ukraine during the Renaissance period and defining the conceptual ideas represented by these concepts. The relevance of this research is explained by the fact that the Renaissance authors appeal to the concepts significant for any epoch. The specifics of the interpretation of history and its representation in the artistic perceptions of the authors of this period are based on an authentic tradition, the European Renaissance trends, and the revival of ancient heritage. In general, the study is grounded on the semantic-cognitive analysis of the works of Renaissance representatives working on the that-time territory of Ukraine (Adam Chagrovsky, Mikolaj Hussowski, Martin Pashkovsky, Sebastian Klonowic, Szymon Pekala, Maciej Stryjkowski, and Stanislaw Orikhovsky). The conceptual fields of each concept selected for analysis were developed in accordance with the individuality of the notions by which Renaissance authors described them. In sum, this paper argues that the worldview of Ukrainian Renaissance litterateurs is characterized by the awareness of the sociopolitical and cultural-literary need to write about history, its role, and place in the context of world processes. No less critical here is their understanding of the mission of personality in history and the analysis of the activities of historical figures and the reality of that time. Thus, the work of Renaissance authors is predominantly characterized by an expressive anthropocentric, humanistic, and patriotic direction. The practical significance of this research lies in the possibility of applying the semantic-cognitive approach to the analysis of leading concepts in Renaissance creativity.
Paradiplomacy in Nigeria’s First Republic: The Uneasy Balance between Faith and National Interest
Authors:   Ajayi Crowther University, Oyo, Nigeria, Faseke Babajimi Oladipo
Published: May 2022

The study investigates the place of religion in the paradiplomacy that was practised in Nigeria’s first republic (1960-1966). It examines how the Northern regional government in Nigeria’s first republic engaged in external relations in furtherance of its narrow interests, which were mostly informed by Islam. During the first republic, Nigeria adopted a federal system of government in which the component units (or regions) wielded enormous influences. Some of these influences translated into external relations although foreign policy was constitutionally an exclusive preserve of the federal government. The practice of a regional government conducting its international relations while remaining within a sovereign nation falls under the ambit of ‘paradiplomacy’. Thus, this kind of subnational diplomacy is carried out with a view to promote subnational (or regional) interests. This raises the question of the compatibility of the interests of a subnational government with those of the national government, particularly in a country such as Nigeria that is multi-ethnic and multi-religious, with certain regions being predominantly Christian and others Muslim. The study adopts the theory of Social Constructivism as a framework and employs the use of qualitative analysis. The methodology is both historical and descriptive, with data derived from both primary and secondary sources. The primary sources employed include personal communications with retired diplomats as well as newspaper sources and archival materials sourced from the National Archives in Kaduna, Nigeria. Content analysis was also used to ensure accuracy and objectivity. Findings reveal that the government of the Northern Region pursued external policies that placed their region over and above the interest of the Federal Government to the extent of conflicts between the two entities, and religion was a telling factor in how this played out.
Reviewing the Prosperity Tracks After Two Decades of Special Autonomy for Papua
Authors:   Program Studi Ilmu Pemerintahan Fisip, Universitas Selamat Sri, Setiawan Hendy
Published: May 2022

The purpose of this study is to discuss the impact of the implementation of special autonomy which has been running for two decades on welfare in Papua through the public service sector. Law Number 21 of 2001 which became the initial basis for the implementation of special autonomy in Papua is an instrument to encourage Papua to catch up with other regions in Indonesia. So far, Papua has been an area that tends to be left behind in various sectors, including its public services. Therefore, the presence of special autonomy, which is then followed by special autonomy funding that significantly increases every year, is expected to be able to improve public services to achieve prosperity. This study uses a qualitative method with a literature study approach. Data were collected from various literature, both from relevant agencies and the relevant media. Meanwhile, researchers in conducting research stages use the Creswell concept. The stages of this research consist of problem identification, literature search, research aims and objectives, data collection, data analysis and interpretation, and research reporting. The results of the study show that two decades of implementing special autonomy in Papua have not provided significant achievements for public services. High poverty rates, low Human Development Index and minimal public service facilities are still the main characteristics of the implementation after the two decades of autonomy. The implication is that there is a negative correlation between the implementation of this special autonomy and the welfare aspect to date. Therefore, the disbursement of funds that enter from the centre to the regions through this regulatory scheme has not had a significant impact on welfare in Papua.
Online Learning Strategies amid New Normal Era in Indonesia
Authors:   Universitas Mahasaraswati Denpasar, Mantra Ida Bagus Nyoman , Handayani Nengah Dwi ,   Universitas Mahasaraswati Denpasar, Pramawati Anak Agung Istri Yudhi ,   Universitas Mahasaraswati Denpasar
Published: May 2022

Many aspects of life have to be reorganized as an impact of the Covid-19 pandemic. The application of physical distancing for the world of education forced the learning activities to be conducted through online systems. In the beginning, online learning was a highly difficult challenge for most educators, because they were unfamiliar with online learning and some of them were doubtful about the effectiveness of online learning. Consequently, many teachers implemented whatever learning strategies they thought to be effective to improve students’ learning achievement. This study explored effective learning strategies used by educators in Indonesia during the new normal era of Covid-19. This study used a mixed-method research design, and the data were collected by using a questionnaire and interviews. 216 respondents participated in this study consisting of university lecturers and schoolteachers. The collected data were then critically analysed, and the findings were described descriptively. This study revealed that educators mostly used online learning, blended learning, project-based learning, and limited face-to-face learning to continually enhance students’ learning competence. This study implies that teachers should creatively develop the existing teaching strategies to suit students’ learning conditions.
Strategies of Teaching and Learning Process for Young Learners during the Pandemic
Authors:   Universitas Pendidikan Ganesha, Ariani Dewi , Padmadewi Ni Nyoman ,   Graduate Program Language Education, Universitas Pendidikan Ganesha, Artini Luh Putu ,   Graduate Program Language Education, Universitas Pendidikan Ganesha
Published: May 2022

This study was conducted to investigate the strategy and activities in the teaching and learning process during the pandemic in Aura Sukma Insani Kindergarten and to investigate the teachers’ problems during the process of teaching English to Young Learners during the pandemic. This research used a descriptive qualitative method, i.e., case study. The research data are derived from observation, interview, documentation, and document analysis. The subject of this research was 3 classes (with 18-21 students each class) in B level (age 5-7). The interview is semi-structured with three teachers and a school principal as informants. The theory used in this research is the teaching and learning theory from Brown (2001). This study concluded that Aura Sukma Insani Kindergarten applied blended learning and applied both synchronous and asynchronous modes of learning during pandemics. Besides, to support the teaching and learning process, the school has a special program namely, orientation and induction programs, and reflection and follow-up program. In addition, the problems of teachers are mainly about the adaptation, emotional bonding, limited time allotment, students’ mood and focus, students’ social skill and characters, teachers’ preparation, parents’ involvement, lack of facilities and technical skill and cost. The results of this study have important implications for classroom practice as it can be used as a resource and as the foundation for more detailed information strategy of the teaching and learning process during the pandemic.
The Effect of Cheating Culture on the Implementation of State Defense at Politeknik Negeri Jakarta
Authors:   Electrical Engineering, Politeknik Negeri Jakarta, Vashti Respati Prajna , Adiwinata Syan Rosyid ,   Electrical Engineering, Politeknik Negeri Jakarta, Sbastian Nesta ,   Electrical Engineering, Politeknik Negeri Jakarta
Published: May 2022

Based on the results of observations to students, it was found that cheating is an entrenched habit among students. This is not in line with the efforts made to avoid cheating, including by preparing to study before the exam to understand the material better. This study aims to determine the effect of cheating culture on students, as an implementation of state defence. This study uses a quantitative descriptive method with the type of survey research. Conclusions are made through the analysis of questionnaires from respondents. The data sources are taken from 3rd-semester students. The sample is determined by using random sampling, the student population is 150 students which is divided into 7 engineering and non-engineering students. The result of this study shows that 87.8% of students had cheated with the factors of lack of self-confidence and fear of bad grades. Then, 99% of students stated that honesty is one of the behaviours that can reduce the cheating habit. Honesty is considered as a form of state defence implementation at Jakarta State Polytechnic students which must be carried out consistently, as the goal of forming national character can be achieved as an effort to face challenges in the future.
Bandung Manufacturing Polytechnic Challenges in Achieving National and International Quality
Authors:   Postgraduate Program of Public Administration Doctoral Study Program, Universitas Diponegoro, Sadikin Supriyadi , Kismartini Kismartini ,   Postgraduate Program, Universitas Diponegoro, Astuti Retno Sunu ,   Postgraduate Program, Universitas Diponegoro, Susanta Hari ,   Postgraduate Program, Universitas Diponegoro
Published: May 2022

The issue of quality is a critical issue for Polytechnics in Indonesia because of the increasing demands of society on institutional performance, therefore Universities need quality assurance as a measure to assess their success or failure. In this context, the role of leadership in every organization is very dominant in developing and increasing the competitiveness of the organization. This study aims to examine the implementation of the system and formulate a management synchronization strategy between ISO 9001:2015 and SPMI to support SPME BAN-PT. This research uses the desk research method. This research method consists of three main stages, namely the standard interpretation stage, the analysis stage and the standard integration stage. The results of this study indicate that in compiling the synchronization of the ISO 9001:2015 and SPMI systems. From the conformity table of the Integration Structure of QMS ISO 9001:2015 and SPMI, it can be seen that the requirements of the ISO 9001:2015 Quality Management System and SPMI complement each other, following the requirements of the Higher Education accreditation criteria set by BAN-PT. With an integrated quality management system and consistently applied by Polman Bandung management, as a leader in this organization will increase the effectiveness in achieving institutional excellence, increase competitiveness and ensure sustainability in facing challenges and increasingly fierce competition in the world of education, both nationally and internationally.
Perfil del emprendedor del norte del Ecuador
Authors: Cahuasquí Cevallos Edwin Marcelo
Published: May 2022

El propósito de esta investigación es determinar el perfil personal, educativo y socio-productivo del pequeño y mediano emprendedor de la frontera norte ecuatoriana y el contexto donde se desarrolla. Esta investigación sirve como punto de partida para que las instituciones involucradas en el tema adopten propuestas y estrategias pertinentes y coherentes, que logren un impacto positivo en el desarrollo del emprendimiento en la zona. Además, permite que las instituciones puedan direccionar sus estrategias en función de los requerimientos reales de estos empresarios y de las necesidades especialmente de formación del pequeño y mediano emprendedor. La investigación comprende un análisis sobre la conceptualización del emprendimiento, desde una óptica epistemológica, un análisis crítico del emprendimiento en el norte del Ecuador, y la descripción detallada del perfil del emprendedor de esta zona.
Frame for a Sultan
Authors: Schroeder Rossitza
Published: May 2022

This essay explores the iconography and significance of the painted frame in the 1480 portrait of the Ottoman sultan Mehmed II by the Venetian artist Gentile Bellini. The frame is lavishly polymorphous and functions as an encomium of sorts, a visual praise that sets the royal figure apart and propels it into the realm of the holy. The sultan internalized as well as institutionalized the distant, unapproachable persona of the late Byzantine emperors and, like them, retreated behind elaborate ceremonial and precious materials. Bellini responded to these circumstances and granted the sultan the status of semi-divine being while synthesizing Italian and Byzantine traditions of enshrinement of sacred images and matter.
A Reconsideration of the Communion of the Apostles in Byzantine Art
Authors: Marinis Vasileios
Published: May 2022

This essay concerns itself with the meaning and function of the Communion of the Apostles in Byzantine monumental painting. Scholars have often interpreted the scene as a liturgical reimagining of the Last Supper, aimed at creating a mimetic relationship between ritual and image, or between the liturgical act and its heavenly prototype. In contrast, based on the history of the scene in illuminated manuscripts, the accompanying inscriptions, and commentaries on the liturgy, I argue that the Communion of the Apostles is an illustration of the historical institution of the Eucharist and has little to do with the everyday liturgical praxis. This continues to be the case even when, in the beginning of the fourteenth century, Christ appears in such paintings wearing patriarchal vestments as the Great Archpriest. I maintain that this new element is rather a manifestation and an advertisement of the enhanced political and religious status of the ecumenical patriarch in the Late Byzantine period.
Amy Neff. A Soul’s Journey: Franciscan Art, Theology, and Devotion in the “Supplicationes variae”
Authors: Corrie Rebecca
Published: May 2022

Review of Amy Neff. A Soul’s Journey: Franciscan Art, Theology, and Devotion in the “Supplicationes variae," by Rebecca W. Corrie
Metapainting in Fourteenth-Century Byzantium and Italy: Performing Devotion Through Time and Space
Authors: Puma Giulia , Rossi Maria Alessia
Published: May 2022

Metaimages have benefited from scholarly attention in recent decades, but not all periods and geographical areas have received equal attention. Most importantly, no comparative studies have been conducted with respect to late medieval Byzantium and Italy. This essay is the first attempt to investigate one instance of these reflexive images—that is, metapaintings—from a comparative point of view, highlighting how they are visually structured and the meanings they convey in each tradition. We explore the logic of metapainting, starting with the historical dimension of the scenes, then the transcendent and eternal power of the enshrined devices, and finally their reflection of contemporary devotion and the active role of the late medieval viewer. By unfolding these three dimensions, this essay argues that the meta in metapainting is the images’ ability to connect the fourteenth-century viewer to a historical and prestigious past that they visually celebrate, but also to testify to the power of devotional images and their performances in a permanent way for any viewer at any given time.
Sonja Drimmer. The Art of Allusion: Illuminators and the Making of English Literature, 1403–1476
Authors: Kuskin William
Published: May 2022

Review of Sonja Drimmer. The Art of Allusion: Illuminators and the Making of English Literature, 1403–1476, by William Kuskin
Tendencias en el comercio internacional de servicios
Authors: Comercio Internacional de Servicios y Comercio Digital Subdirección General de
Published: May 2022

Este trabajo presenta una panorámica general sobre el comercio internacional de servicios, sus implicaciones, repercusiones y trascendencia, y ejemplifica los desarrollos llevados a cabo en las últimas décadas en pos de su liberalización y regularización.

Un repaso por las diferentes iniciativas y avances que, tanto en el ámbito multilateral como plurilateral, han tenido lugar recientemente, da paso al desarrollo profundo de la denominada «Iniciativa plurilateral sobre reglamentación nacional de los servicios», una de las iniciativas que, dentro de la Organización Mundial del Comercio (OMC), más éxito han tenido tras la última Conferencia Ministerial (CM11), y cuyos beneficios para las empresas proveedoras de servicios se estiman en 135.000 millones de dólares.
The first data on international multicenter clinical study RheoSTAT-CP0620 on the efficacy and safety of Rheosorbilact® infusion in therapy of sepsis
Authors: Sharipova V.Kh. , Beridze S. , Pidmurniak O.O. , Shanazarov N.A. , Kobeliatskyi Yu.Yu. , Koshlya V.І. , Peev S.B. , Babunashvili N. , Cojocaru V. , Bely A. , Kanikovskyi O.Ye. , Pyrtsak I.
Published: May 2022

Sepsis stays a common and life-threatening pathological condition; hospital mortality in patients with sepsis exceeds 30 %. Fluid resuscitation is an important component of sepsis treatment. The purpose of this work was to evaluate the efficacy and safety of the multicomponent infusion solution Rheosorbilact in the treatment of patients with sepsis. The international multicenter randomized study RheoSTAT-CP0620 included 180 patients aged 18 to 60 years diagnosed with sepsis. Patients received Rheosorbilact therapy in dosage according to the package insert. A change in the SOFA score on day 3 of treatment was considered to be the primary endpoint. Changes in APACHE II, SAPS II, and MODS scores, as well as changes in endogenous intoxication markers on day 3 of treatment, were considered the secondary endpoints. The safety of the drug was assessed by analysis of adverse events and vital signs after 3 days of therapy. On day 3 of Rheosorbilact treatment, statistically significant changes in SOFA (by 2.01±1.37 points), APACHE II (by 4.24±3.76 points), SAPS II (by 3.40±5.30 points), and MODS (by 1.37±1.37 points) scales were recorded. In addition, there was a statistically significant improvement in markers of endogenous intoxication (urea, creatinine and total bilirubin concentrations, leukocyte counts, and calculated intoxication indices) on day 3 of treatment. The majority of adverse events (71.74 %) were mild. None of the adverse events were related to the study drug and did not result in the patient’s withdrawal from the study. According to the results of RheoSTAT-CP0620, Rheosorbilact is an effective and safe drug for the treatment of patients with sepsis. It is advisable to include Rheosorbilact in routine treatment algorithms for patients with sepsis.
Los estilos de aprendizaje VARK en aula virtual universitaria; una herramienta para la mejora del rendimiento académico
Authors: Flores Pizarro Isaac
Published: May 2022

Los estudiantes en un nivel universitario muestran dificultades para abordar material en una sola presentación que no es afín a su estilo de aprendizaje, lo cual dificulta la labor docente de transmitir conocimiento en un aula virtual, donde el contacto con el maestro es menor. El objetivo de la investigación busca describir el impacto de la implementación de un aula virtual multimodal con materiales presentados según los distintos estilos de aprendizaje de los alumnos, así como describir sus experiencias durante la implementación de esta. Se desarrolla un entorno de aprendizaje multimodal adaptable a las necesidades cognitivas de los alumnos con el fin de mejorar el rendimiento académico. Se utilizó el cuestionario VARK de Fleming y una entrevista semiestructurada para evaluar la experiencia del alumno. Ante este entorno de aprendizaje, los alumnos muestran una mayor motivación y rendimiento académico al presentarles un aula virtual multimodal debido a que los materiales propuestos les resultaron de fácil entendimiento, y a su vez, gracias a esto, los estudiantes sintieron un mayor interés por parte del profesor, creando reciprocidad en el desempeño del curso. Esto significa que la implementación de esta estrategia propicia el aprendizaje autónomo, de manera que los contenidos abordados se conviertan en aprendizaje significativo, lo cual se refleja en la calidad educativa.
Validez de constructo del instrumento para evaluar el trabajo docente en la organización de clase (IEOC)
Authors: Ochoa Martínez Oscar Luis , Cháidez Nevárez Belia
Published: May 2022

El objetivo de este trabajo consistió en determinar la validez de constructo del instrumento que se construyó para evaluar el trabajo docente en la organización de clase (IEOC), este instrumento se desprendió de la dimensión “organización de la clase”; parte del instrumento que se elaboró para medir el aprendizaje del docente, producto del proceso de evaluación al desempeño (IEAD), cuya autoría pertenece al autor del presente trabajo. El estudio se consideró de tipo instrumental, para la recolección de datos se utilizó una muestra de carácter intencional con 108 participantes, figuras académicas que participaron en la aplicación del IEAD, y por consiguiente, del IEOC. En el resultado de validez de constructo que se efectuó a través de la prueba de correlación “dominio total” se obtuvo un valor del coeficiente Rho de Spearman de 0.973, valor considerado como “excelente” e indicativo de la asociación entre las variables operativas en el estudio del IEOC. Respecto a la prueba de validez confirmatoria que se realizó a través de la prueba de regresión lineal, también se obtuvo información que avaló este resultado, pues el valor del coeficiente de determinación R2 indicó que la variable independiente explica en un 95.4% el comportamiento de la variable dependiente. Otro resultado que aportó sustento a la validez del IEOC fue el estadístico de Durbin-Watson que se obtuvo en esta misma prueba, el valor de “D” fue 2.06, cercano al ideal “2”...
La psicomotricidad en los procesos de aprendizaje en la atención a la diversidad
Authors: Valles César Delgado , Oros Macías Ruth Nohemí , Cruz Urías Beatriz Angélica
Published: May 2022

Trabajar la psicomotricidad en el aprendizaje, permite que las y los docentes en formación adquieran los elementos básicos para el desarrollo de estrategias de intervención en la atención a la diversidad y a la par ofrecer una educación de excelencia; considerando que esta materia se aborda de forma transversal a lo largo de Licenciatura en Inclusión Educativa, se observaron diversas áreas de oportunidad las cuales fueron investigadas a través de la opinión de maestros en servicio. El objetivo del presente estudio fue identificar la percepción de un grupo de egresados de la Licenciatura en Educación Especial de las Institución Benemérita y Centenaria Escuela Normal del Estado de Chihuahua –IByCENECH– sobre el impacto de los objetos de aprendizaje en su quehacer docente. La metodología del estudio es de tipo cuantitativo, transversal y descriptivo, se aplicó un cuestionario informatizado tipo encuesta con apoyo de la plataforma de Google Formularios. Se obtiene como resultado el menester de fortalecer la formación de los futuros profesores en relación a la atención de las y los estudiantes a través de la psicomotricidad y su impacto en el aprendizaje, así mismo la construcción de una materia que ofrezca los objetos de aprendizaje relacionados con dicha temática, concluyendo con la necesidad de generar un curso en el que se impartan las bases y conceptos relacionados con el desarrollo motor y la psicomotricidad en el ámbito de la inclusión educativa.
Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells
Authors: Warsi Sarah , Dahl Maria , Smith Emma M. K. , Rydstrom Anna , Mansell Els , Sigurdsson Valgardur , Sjoberg Julia , Soneji Shamit , Rorby Emma , Siva Kavitha , Grahn Tan H. M. , Liu Yang , Blank Ulrika , Karlsson Goran , Karlsson Stefan
Published: May 2022

Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the immense importance of this quiescent state, its maintenance and regulation is still incompletely understood. Schlafen2 (Slfn2) is a cytoplasmic protein known to be involved in cell proliferation, differentiation, quiescence, interferon response, and regulation of the immune system. Interestingly, Slfn2 is highly expressed in primitive hematopoietic cells. In order to investigate the role of Slfn2 in the regulation of HSC we have studied HSC function in the elektra mouse model, where the elektra allele of the Slfn2 gene contains a point mutation causing loss of function of the Slfn2 protein. We found that homozygosity for the elektra allele caused a decrease of primitive hematopoietic compartments in murine bone marrow. We further found that transplantation of elektra bone marrow and purified HSC resulted in a significantly reduced regenerative capacity of HSC in competitive transplantation settings. Importantly, we found that a significantly higher fraction of elektra HSC (as compared to wild-type HSC) were actively cycling, suggesting that the mutation in Slfn2 increases HSC proliferation. This additionally caused an increased amount of apoptotic stem and progenitor cells. Taken together, our findings demonstrate that dysregulation of Slfn2 results in a functional deficiency of primitive hematopoietic cells, which is particularly reflected by a drastically impaired ability to reconstitute the hematopoietic system following transplantation and an increase in HSC proliferation. This study thus identifies Slfn2 as a novel and critical regulator of adult HSC and HSC quiescence.
Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease
Authors: Khasabova Iryna A. , Gable Jacob , Johns Malcolm , Khasabov Sergey G. , Kalyuzhny Alexander E. , Golovko Mikhail Y. , Golovko Svetlana A. , Kiven Stacy , Gupta Kalpna , Seybold Virginia S. , Simone Donald A.
Published: May 2022

Sickle cell disease (SCD) is the most common inherited disease. Pain is a key morbidity of SCD and opioids are the main treatment but their side effects emphasize the need for new analgesic approaches. Humanized transgenic mouse models have been instructive in understanding the pathobiology of SCD and mechanisms of pain. Homozygous (HbSS) Berkley mice express >99% human sickle hemoglobin and several features of clinical SCD including hyperalgesia. Previously, we reported that the endocannabinoid 2-arachidonoylglycerol (2-AG) is a precursor of the pro-nociceptive mediator prostaglandin E2-glyceryl ester (PGE2-G) which contributes to hyperalgesia in SCD. We now demonstrate the causal role of 2-AG in hyperalgesia in sickle mice. Hyperalgesia in HbSS mice correlated with elevated levels of 2-AG in plasma, its synthesizing enzyme diacylglycerol lipase β (DAGLβ) in blood cells, and with elevated levels of PGE2 and PGE2-G, pronociceptive derivatives of 2-AG. A single intravenous injection of 2-AG produced hyperalgesia in non-hyperalgesic HbSS mice, but not in control (HbAA) mice expressing normal human HbA. JZL184, an inhibitor of 2-AG hydrolysis, also produced hyperalgesia in non-hyperalgesic HbSS or hemizygous (HbAS) mice, but did not influence hyperalgesia in hyperalgesic HbSS mice. Systemic and intraplantar administration of KT109, an inhibitor of DAGLβ, decreased mechanical and heat hyperalgesia in HbSS mice. The decrease in hyperalgesia was accompanied by reductions in 2-AG, PGE2 and PGE2-G in the blood. These results indicate that maintaining the physiological level of 2-AG in the blood by targeting DAGLβ may be a novel and effective approach to treat pain in SCD.
Anti-MRSA activity of Pollianthes tuberosa leaf extracts
Authors: Sundar Ranjitha Dhevi V. , Arunachalam Sathiavelu
Published: May 2022

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Temperature-Dependent Changes in Gamma Irradiated Porcine Gelatin with Low Bloom (PGL) Value: an ESR Investigation
Authors: Rao N. S. , Shireesh D. , Kalahasti S. , Rao B. S.
Published: May 2022

Gamma irradiation of Gelatin brings important changes in its chemical structure, making it suitable for different applications. The irradiated Gelatin may be subjected to different thermal treatments during these applications. Therefore, temperature-dependent changes in irradiated gelatins are a point of interest. Electron spin resonance (ESR) is vital for detecting free radical processes in irradiated polymers. As such, ESR spectra of temperature-dependent porcine Gelatin with low bloom are recorded, and they are analyzed by computer simulation techniques. Component spectra under different conditions are evaluated by the magnetic parameters employed to simulate the ESR spectra. The results indicate that the spectral shape at 300 K (RT) is stable up to 350 K, and signal intensity begins to decay beyond 350 K. The signal vanished around 355 K, designated as radical decay temperature. Bloch analysis is applied to evaluate activation energy associated with free radical decay, calculated around 35 KJ/mole.
Synthesis Method of Hemp-Derived Graphene
Authors: Hossain M. Z. , Sutradhar S. , Karim M. R.
Published: May 2022

Graphene has attracted great attention to researchers nowadays for its electronic, optical, and mechanical properties. A key requirement for applications is the development of industrial-scale, reliable, and inexpensive production processes.  In this work, we present a scalable approach of graphene synthesis from a biomass source such as hemp bat fiber which is called hemp bast fiber derived graphene (HGr). The structure and morphology of HGr are confirmed by performing several characterization techniques such as XRD, Raman spectroscopy, and TEM analysis. Mesoporosity of the HGr is confirmed by BET surface area and BJH pore size distribution analysis.
Epidemiologic and clinical characteristics of COVID-19 patients admitted in a tertiary care hospital in Khulna city
Authors: Haque Syed Didarul , Kabir Muhammad Ashraful , Biswas Prithwy Shankar , Al Amin Abu Md Mayeenuddin , Ali Md Barkot , Islam Baishakhi
Published: May 2022

Background & objective: The outbreak of coronavirus disease 2019 (COVID-19) has become a large threat to global health due to its high contagious nature and varied mortality. The number of infected cases and deaths are rising exponentially all over the world, including Bangladesh. This study aims to investigate the epidemiological and clinical features of COVID-19 patients admitted in Gazi Medical College Hospital (GMCH), Khulna, Bangladesh.
Methods: In this study, we included 110 RT-PCR positive COVID-19 cases at GMCH, Khulna, Bangladesh from 1 July, 2021 to 31 August, 2021. Demographic, clinical, laboratory and radiological data of the patients were recorded and analyzed.
Results: Among 110 study subjects, 51.8% were male. The mean age was 52.6 years, with majority (43.6%) belonging to the age group of 40-59 years. Upon admission, the most frequent symptoms were fever (94.5%), cough (86.4%) and dyspnea (79.1%). Diabetes mellitus (42.7%) and hypertension (33.6%) were the most common comorbidities. Regarding laboratory parameters, neutrophilia and lymphocytopenia were observed in 72.7% and 58.2% cases, respectively. The mean D-dimer (2.9 mg/l) and CRP (61.7 mg/l) levels were above their normal limits. In high resolution CT scan of the chest (HRCT chest), bilateral lung involvement was present in 85.5% cases. Ground-glass appearance was the most frequent (89.1%) radiologic pattern. Among the study subjects, empirical antibiotic, antiviral (remdesivir) drug, and systemic glucocorticoid were given to 97.3%, 83.6% and 56.4% patients, respectively. Total 15 (13.6%) patients were severely affected with COVID-19 and admitted to the ICU, requiring mechanical ventilation. During our study, 12 patients (10.9%) died either due to multiple organ dysfunction syndrome or cardio-respiratory failure.
Conclusion: The study provides key information about clinical characteristics and general management of COVID-19 patients, which may help physicians to identify the factors associated with adverse outcomes in this disease.
Mediscope 2022;9(1): 9-15
Pattern and outcome of electrolytes imbalance in acute stroke patients admitted in a tertiary care hospital in Khulna city
Authors: Kabir Muhammad Ashraful , Islam Baishakhi , Rahman Tasnim , Ghosh Kakali Rani
Published: May 2022

Stroke is a major public health problem and a leading cause of chronic disability and death. There is scarcity of data about electrolytic disturbances in acute stroke, especially in developing countries. The objective of this study is to find out electrolyte disturbances among acute stroke patients and their association with severity of acute stroke and outcome. It was a cross-sectional study, conducted over a period of one year from 01/06/2018 to 31/05/2019, on 80 selected clinically and CT scan proven acute stroke patients at Gazi Medical College Hospital, Khulna. Out of 80 patients, 50 (62.5%) were male and 30 (37.5%) were female. Majority of the patients (38.7%) were above 70 years age group. CT scan findings revealed, 16 (20%) haemorrhagic, 60 (75%) ischaemic and 4 (05%) mixed (both haemorrhagic and ischaemic) stroke. Seventy-two (90%) of patients had unilateral and only 8 (10%) had bilateral lesion. Dyselectrolytemia was evident in 65% of total stroke patients. Thirty-five percent of all patients had hypokalaemia which was the most common dyselectrolytemia. Out of 20 patients with hyponatremia, 14 died and out of 28 patients with hypokalaemia, 14 died. Out of total 80 patients 48 (60%) had improved and 4 (5%) had been unchanged and referred to higher centre.
Mediscope 2022;9(1): 20-24
A.İ. KUPRİN’İN “GRANAT BİLEZİK” İLE H. Z. UŞAKLIGİL’İN “MAİ VE SİYAH” ESERLERİNDE “AŞK” KAVRAMI
Authors: USTA Elif , RAMAZANOVA Shalala, Shelale, Şelale
Published: May 2022

Bu çalışmada Rus edebiyatının ünlü yazarlarından olan Aleksandr İvanoviç Kuprin tarafından 1910 yılında yayımlanan “Granat Bilezik” öyküsü ileTürk edebiyatının usta romancısı Halit Ziya Uşaklıgil’in 1889 yılında kaleme aldığı “Mâi ve Siyah” adlı romanında “aşk” kavramı karşılaştırılarak ortayakonulmaya çalışılmıştır. Çalışmada ele aldığımız aşk kavramı, yazımızın temelini oluşturmaktadır.Aşk, gelişen, ilerleyen ve son bulabilen bir duygudur. Bir kişinin içinde kisevme yeteneği her zaman var olmuştur ve bu duygu kişinin hayatındaki gelişimsüreci ile doğru orantılıdır.Âşık olmak bir insanın sevdiği kişiye ve dünyaya olan bakışını değiştirdiğigibi bir insana coşku ve depresyon gibi uç duygular da yaşatabilir. Aşkzıtlıklarla doludur: belirsizdir- Aşk bazen kişinin partnerine karşı duyduğu birsevgide nefret barındırırken, bazen de verdiği hazla birlikte kişiye ıstırap çektirebilir.Genel olarak aşkın yaşattığı hissiyatın doruk noktasının zevk olduğunave özünün tamamlayıcılıkta yattığına inanılmaktadır. Bu çalışmada ele aldığımız“Granat Bilezik” ile “Mai ve Siyah” eserlerinde yazarlar tarafından duygusalbağlamda işlenmiş aşk ele alınacaktır.Çalışmanın amacı: Rus ve Türk edebiyatındaki önemli yazarlar tarafındankaleme alınmış iki eserde incelenen konunun ortak ve farklı yönlerini ortayakoymaktır. Aleksandr İvanoviç Kuprin’in “Granat Bilezik” ve Halit Ziya Uşaklıgil’in“Mai ve Siyah” eserleri üzerine karşılaştırmalı olarak aşk kavramının ilkdefa incelenmesi ise çalışmanın yeniliğidir. Bu çalışmada; tanımlama, karşılaştırma,genelleme ve çeviri yöntemleri kullanılmıştır.
Polimer Ve Hümik Asit Uygulamalarının Toprağın Strüktürel Gelişimi Üzerine Etkileri
Authors: KASSIM Hachim , ÖZDEMİR Nutullah
Published: May 2022

Günümüzde kullanılan tarımsal yöntemler sebebiyle topraklar üretim kapasitelerini kaybedip önemli düzeyde bozulmaya maruz kalmaktadırlar. İyi gelişmiş bir strüktür ve yüksek agregat stabilitesine sahip bir toprak yapısı, verimliliğin artırılması ve aşınabilirliğin azaltması açından oldukça önemlidir. Bu çalışma, polivinil alkol (PVA), poliakrilamid (PAM) ve hümik asit (HA) uygulamalarının toprakta bazı strüktürel parametrelerin (agregat stabilitesi ve dispersiyon oranı) gelişimi üzerine etkilerini belirlemek amacıyla sera şartlarında yürütülmüştür. Araştırmada üç farklı tekstüre sahip (kil, tın ve kumlu tın) yüzey toprak örnekleri kullanılmıştır. Serada, 1 kg’lık saksılara aktarılan toprak örneklerine PVA, PAM ve HA sırasıyla 500, 100 ve 500 ppm dozlarında uygulanmış ve dört farklı periyotta (0, 15, 30 ve 45 gün) inkübasyona tabi tutulmuştur. İnkübasyon sırasında topraklardaki elverişli nemin %50’si tükenince sulama yapılmıştır. İnkübasyon tamamlandıktan sonra toprakların yapısal parametreleri üzerinde analizler ve değerlendirmeler yapılmıştır. Elde edilen sonuçlar; killi, tınlı ve kumlu tınlı topraklara PVA, PAM ve HA uygulamasının suya dayanıklı agregatlar miktarını denete göre (ortalama) sırasıyla %5,38, %6,34 ve %12,91 oranında artırdığını göstermektedir. Dispersiyon oranı değerlerini (ortalama olarak) ise sırasıyla %46,56, %8,11 ve %12,91 oranında azalttığını göstermektedir. Agregat stabilitesini arttırmada 1 nolu periyot (24.52), dispersiyon oranı değerini düşürmede 2 nolu peryot (29.92) en etkili dönemler olarak belirlenmiştir. Süre uzadıkça etkinliğin düştüğü tespit edilmiştir. Her üç toprak grubunda da PVA'nın en etkili düzenleyici olduğu belirlenmiştir.
Qualidade fitossanitária e germinativa de sementes de milho submetidas à termoterapia
Authors: Raad Sayure Mariana , Ribeiro Erick dos Santos , Brandão Vilani Gusmão da Silva , Castro Rayanne de Jesus , Pereira Amanda de Nazaré Rodrigues , Cid Yan Patrick Moita , Amaral Ana Paula Magno do , Moraes Ana Claudia Corrêa , Tavares Lilian Conceição , Carneiro Francimary da Silva
Published: May 2022

Este presente trabalho teve por objetivo avaliar a eficiência da termoterapia no controle de patógenos de sementes de milho e seu poder germinativo. O mesmo foi desenvolvido no laboratório de Fitopatologia da Universidade Federal Rural da Amazônia, Campus Belém, PA. Para isso, o delineamento experimental utilizado foi o inteiramente casualizado(DIC), com 6 tratamentos e cinco repetições, cada repetição foi composta por um lote de 20 sementes. Os tratamentos térmicos empregados foram por imersão em água aquecida nas seguintes temperaturas: 40 oC, 50 oC, 60 oC, 70 oC e 80 oC, sendo denominados, T2, T3, T4, T5, T6 e T7, respectivamente. Após as sementes serem submetidas aos tratamentos, analisou-se a sanidade para a determinação da eficiência dos tratamentos na redução fúngica das sementes e germinação. A termoterapia mostrou-se eficiente em relação a testemunha em todos os tratamentos na redução fúngica das sementes, dando destaque para os tratamentos T5 e T6. Na germinação, esse método obteve resultados positivos nos tratamentos T2 e T3, obtendo 60% e 98% de germinação em relação a testemunha. Com isso, a termoterapia demostrou ser um método alternativo positivo na redução do potencial fúngico das sementes de milho e no aumento do poder germinativo em determinadas temperaturas.
Otimização do processo de destilação por mudança de pressão com corrente intermediária para separação da mistura azeotrópica Éter Diisopropílico/Álcool Isopropílico
Authors: Silva Lucas Medeiros da , Martins Júnior Marcos Cesar , Ramos Wagner Brandão
Published: May 2022

No que tangencia os processos industriais, a necessidade pela redução da alta demanda energética associada ao processo de destilação se torna progressivamente imprescindível. Além disso, é crescente a necessidade de trabalhar com plantas cada vez mais compactas, objetivando a diminuição dos custos de instalações. O éter diisopropílico (DIPE) é um subproduto gerado na produção de álcool isopropílico (IPA), ambos os componentes possuem alto valor agregado, principalmente na indústria de solventes, ou seja, a separação desse binário é economicamente atrativa. Essa separação necessita de um método não-convencional, pois apresenta formação de um ponto azeotrópico, sendo este com mínimo ponto de ebulição. O presente trabalho teve como objetivo otimizar o processo de separação desse binário homogêneo através da destilação pressure-swing com conexão intermediária (PSDIC). Para atingir o objetivo, o processo PSDIC foi simulado utilizando o software Aspen Plus® e a otimização foi realizada utilizando o método do Algoritmo de Recozimento Simulado (SAA), implementado em uma toolbox no Matlab®. Nove variáveis, divididas entre operacionais e de projeto, foram otimizadas simultaneamente, de modo a se obter um cenário otimizado para o processo PSDIC em termos do Custo Anual Total (TAC). A configuração com a melhor TAC apresentou uma economia de 4,47% ao ano e uma redução na carga térmica da coluna de alta pressão em 2,47%, em relação à configuração base. A inserção da corrente de conexão intermediária contribuiu para a redução da TAC para o processo avaliado.