bluuebunny/crossref_metadata_2025 huggingface dataset:
CLINICOPATHOLOGICAL STUDY ON RARE MALIGNANT TUMORS OF PAROTID GLAND AND COMPREHENSIVE REVIEW ON NEWER ENTITIES OF SALIVARY GLAND TUMORS
Authors: Ganga Veena B , Krishnappa Krishnappa
Published: August 2021

Salivary gland tumors are a heterogeneous group of tumors in the head and neck; most of the malignant tumors have a poor prognosis and limited
long-term survival. The recent 2017 WHO classication had made few changes in the sub-categorization and modied some terms. More studies
are underway in the eld of molecular level changes and responses to targeted therapies in these tumors. These researches have shown some
resemblance in the behavior of salivary gland and breast carcinomas, leading to a new line of thinking in terms of hormonal therapy. This study
outlines 14 cases of rare parotid tumors reported in our institute during the time period of 2018 to 2020 and a comprehensive review on salivary
gland tumors, newer entities added, and newer treatment strategies.
CLINICAL PROFILE OF ASTHMA IN MALE SMOKERS
Authors: Singh Pankaj , Tyagi Ashish , Joshi Nalin
Published: August 2021

Introduction: st Asthma is traditionally dened as a functional abnormality with reversibility in forced expiratory volume in 1 second of more than
15% as opposed to irreversible or xed airway limitation in chronic obstructive pulmonary disease (COPD).This study aims to the assess the
clinical symptoms, physical ndings and laboratory results in smoker patients reporting with symptoms suggestive of bronchial asthma .
Material and method: This study was conducted in department of Respiratory Medicine of National institute of Medical sciences and research,
Jaipur on 50 outdoor male smokers presented with respiratory complaints during period of September 2020 to May 2021.
Result: 100 patients enrolled in this study. And 50 patients were diagnosed as bronchial asthma on the basis of steroid trial. Mean age of patients in
our study is 48.00+10.41. Shortness of breath (48%) was the commonest complaint followed by cough(24%), expectoration (20%) and last was
chest pain (8%). There were more current smokers (48%) followed by ex smokers (32%0 and least were reformed (20%).The most common
symptoms in past history of patient was seasonal variation (96%) followed by eye itching (32%), chest tightness (60%), sneezing (56%), dust
allergy(32%), non respiratory allergy and wheeze (24%) and last was positive family history of asthma or allergy.
Past history showed different variation in which any one symptoms was present in 100% of patients, followed by 2 symptoms (95%), 3 symptoms
(84%) and 4 symptoms (52%).
Conclusion: This study concludes that presence of any two of the above described past symptoms or variables suggestive of asthma in past are
diagnostic of asthma in smoker patients even in the presence of irreversible or partially reversible airway obstruction
A Revised Inductance Distribution Analysis of Medium-Large Caliber Electromagnetic Launchers including a Large Bus Structure
Authors: Tosun Nail , Keysan Ozan
Published: August 2021

    

An important application for large-scale pulse power supplies (PPS) is electromagnetic launchers (EMLs). These de- vices utilized stored several MJs of electrochemical energy into linear mechanical energy. Because of extreme physical conditions, simulations are crucial in electromagnetic launcher (EML) research. As the operation risk rises, more en- ergy into the system adds weight to the model’s accuracy. In this paper, the electromagnetic impact of the bus structure is discovered in a recently developed EMFY-3 electromagnetic launcher, is presented. An H-shaped bus structure is used for the current injection. However, experiments showed that the H-shaped bus changes inductance calculations. A careful examination is made to reveal the physical reasoning behind the bus impact. We hypothesize that the rail portion surrounded with bus geometry has less inductance than the rest due to the eddy current created by rail current transients, which should be calculated carefully through numerical calculations, i.e., 3-D Finite Element Method (FEM). Two dif- ferent simulation models were constructed to test the hypothesis. Moreover, rail currents, breech, and muzzle voltages are measured to investigate electromagnetic calculations. Results showed a good agreement with experiments where the bus structure was modeled explicitly. That aspect showed that the bus structure should be well-examined when multiple PPS are connected. 
Petersburska teka osobowa skrzypka Apolinarego Kątskiego jako źródło do badań nad jego biografią
Authors: Antonczyk Wiktoria , Chamczyk Ewa
Published: August 2021

Petersburg, jako jeden z głównych ośrodków kulturalnych XIX-wiecznej Europy, przyciągał światowej sławy artystów, zapraszanych nie tylko na występy gościnne. Podpisali też kontrakty z najważniejszymi instytucjami muzycznymi Imperium Rosyjskiego. Mimo znacznych zniszczeń, jakie miasto doznało w czasie II wojny światowej, w dramatycznych okolicznościach uratowano jego cenne zbiory archiwalne, w tym bogatą dokumentację Dyrekcji Teatrów Imperatorskich. Dokumenty te stanowią niezwykle cenne źródło dla muzykologów, pozwalają bowiem z dużą dokładnością zrekonstruować okres petersburski w twórczości wielu artystów.Dokumenty Dyrekcji Teatrów Imperatorskich stanowią również kluczowe źródło do badań nad biografią polskiego skrzypka-wirtuoza Apolinarego Kątskiego, który w latach 1852-1866 był solistą Jego Imperatorskiej Mości. Fakt ten był dobrze znany, jednak obowiązki wynikające z tego statusu pozostają praktycznie niepoznane. Akta osobowe Kątskiego nie tylko potwierdzają szczególne traktowanie przez władze tego wybitnego polskiego muzyka, ale też ujawniają jego niezwykłe warunki zatrudnienia.Czego zatem dowiadujemy się o życiu Kątskiego z petersburskich dokumentów? Na jakie pytania pozwalają nam odpowiedzieć? Jaki obraz polskiego skrzypka wyłania się z tego źródła? Artykuł przedstawia zawartość akt osobowych Apolinarego Kątskiego w kontekście badań nad jego biografią.
Rafał Ciesielski, Polska krytyka jazzowa XX wieku. Zagadnienia i postawy, Zielona Góra 2017
Authors: Dziadek Magdalena
Published: August 2021

Recenzja książki: Rafał Ciesielski, Polska krytyka jazzowa XX wieku. Zagadnienia i postawy, Zielona Góra 2017
The Influence of Leadership Style, Motivation, and Discipline on Employee Performance of PT Intikom Berlian Mustika
Authors: Heryanti Yani , Ariwibowo Prasetio , Rosadi Nicky
Published: August 2021

This study aims to determine what factors influence the Leadership Style, Motivation, and Discipline on Employee Performance. The method used in this research is quantitative research methods. The population in this study were all employees of PT Intikom Berlian Mustika in the Operation Support section with a sample of all employees of PT Intikom Berlian Mustika in the Operation Support section, except for a leader. The instrument in this study used an open questionnaire using a Likert scale to measure the attitudes, opinions and perceptions of a person or group of social events or symptoms. The results of this study were partially tested for leadership style variables with a statistical value of 1.585 <2.162, so Ho was accepted, meaning that there was no significant effect of the leadership style variable on employee performance. The partial test results for the motivation variable with a statistical value of 1.376 <2.162, then Ho is accepted, which means that there is no significant effect of the motivation variable on employee performance, so Ho is accepted, which means that there is no significant effect of the motivation variable on employee performance. The partial test results for the discipline variable with a statistical value of 5.969> 2.162, then Ho is rejected, which means that there is a significant effect of the discipline variable on employee performance. Simultaneous test results with a value of 19.288> 2.77, then Ho is rejected, which means that leadership style, motivation, and discipline simultaneously or jointly affect the performance of employees of PT Intikom Berlian Mustika.
The Ratio of Added Value to Marginal Land Use of Embankments in Wisata Agribisnis
Authors: Hartati Hartati , Nuryadi Ahmad Muhlis , Rosmalah Sitti
Published: August 2021

The main activity of pond land in Wisata Agribisnis is the cultivation of milkfish. However, to maximize the use of pond land, pond farmers plant dragon fruit plants to add value to land management. The aim of this research is to analyze the value-added ratio on marginal land. This research method is a case study of marginal land use in agribusiness tourism, with qualitative and quantitative data. Quantitative data are analyzed with income analysis and value-added analysis. Qualitative data describe the marginal land use of embankments. The research results of dragon fruit planting in the marginal areas of pond embankments showed: 1) dragon fruit plants do not pollute pond water, this is because the structure of dragon fruit plants is similar to cactus plants, 2) full sunlight in ponds is very suitable for dragon fruit plants, 3) plants dragon fruit is very tolerant of brackish water, 4) the taste of dragon fruit remains sweet in root conditions close to brackish water, 5) dragon fruit plants continue to bear fruit even though planted in marginal land at the embankments of the pond. The results of the research on marginal land use of pond embankments by planting dragon fruit plants added value of Rp. 17,302,857, with a ratio of 85%. Pond farmers can take advantage of the marginal land of their ponds by planting dragon fruit plants.
The Contribution of Oil Palm Partnerships to Increased Income of Plasma Farmers: A Study at PT. Windu Nabatindo Lestari (WNL)
Authors: Kurniawan Indra , Elfatma Olivia , Saloko Subakho Aryo , Setyawan Heri
Published: August 2021

The income level of smallholder farmers can only meet their daily needs due to the location's remote location and the difficulty of communication access. Based on this, the Government seeks to formulate policies that are expected to have a real impact on increasing the productivity of smallholdings and improving the welfare of farmers. One of the efforts made is the Primary Member Cooperative Credit (KKPA). The purpose of this research is to examine the impact of the partnership program at the Windu Nabatindo Lestari (WNL) company in the KKPA scheme, a program to improve the welfare of plasma farmers. The research method is descriptive analysis with a qualitative approach using purposive sampling. Research respondents were 60 plasma farmers. Data collection techniques include field observations, in-depth interviews with questionnaires, and analysis of company documents. The results showed an increase in the welfare of plasma farmers after the partnership program. The partnership program at the Windu Nabatindo Lestari (WNL) company under the KKPA scheme positively impacts the welfare of plasma farmers in Pundu Village, Cempaga Hulu District East Kotawaringin, Central Kalimantan. The frequency of the number of plasma farmers who experienced increased income before and after the KKPA program was 83.3%.
Anhuienoside C Ameliorates Osteoclast Differentiation in Ovariectomy-Induced Osteoporosis by Regulating RANKL/Wnt Signaling Pathways
Authors: Sun Bo , Su Tian , Meng Zhibin , Tang Songjie
Published: August 2021

Postmenopausal and ovariectomy-induced osteoporosis is the most common bone disorder. While pharmacotherapy has been valuable in the management of osteoporosis, it has been associated with undesired side effects. Plant bioactives with minimal side effects have been seen as adjunct to classical therapy. Herein, we have evaluated the protective effect of anhuienoside C (AC) in a rat model of ovariectomy-induced osteoporosis. The treatment of osteoporotic rats with AC caused dose-dependent favorable changes in biochemical markers of bone formation and metabolism (osteocalcin, C-telopeptide of type 1 collagen, and procollagen type 1 N-terminal propeptide), enhanced bone mineral density, and decrease in proinflammatory mediators of inflammation and RANKL/Wnt pathway proteins. Furthermore, histopathologic changes in the tibia support beneficial effects of AC. In conclusion, our result reveals that treatment with AC shows beneficial effect against ovariectomy-induced osteoporosis by regulating the RANKL/Wnt pathway.
OPERATIONAL EFFECTIVENESS OF PYROTECHNIC CARTRIDGES FOR AVIATION METHOD OF LANDING OF WOODS AND OTHER TYPES OF PLANTS
Authors:   Samara State Technical University, Aleksentseva S.E.
Published: August 2021

Efficiency of working out by means of an aviation method of landing of woods and other kinds of plants with application of pyrotechnic cartridges of an ecological material for reset the seeds for its deepening in a soil is shown.It is effected without the sowing transport machines and gears. There is project of landing of woods and other kinds of plants with a pollution-free expedient, without pollution of soil by materials of standard pyrotechnic cartridge. In the article there was collected an information about a capability of operational use of pyrotechnic cartridges made of an ecological material for reset the seeds. Constructive applications of pyrotechnic cartridges for reset of mass of the seeds material by means an aviation technics are investigated. In The article there is exposition of a construction of the pyrotechnic cartridge for distant reset of a seed material in the form of special sheaths and sowing of the extensive areas by seeds of woods and other kinds of plants with high speed and efficiency. there is origin of the forces working on a disrupture of a material of the pyrotechnic cartridge under the influence of pyrotechnic gases. In the article there is the analysis of strength parametres of an ecological material of the pyrotechnic cartridge under the influence of a pressure of burster charge. Calculated parametres of widths of pyrotechnic cartridges for reset of seed loads of different masses are yielded. Components of a pollution-free composition for manufacture of the pyrotechnic cartridge made of the natural materials with the gluing water-soluble materials are offered. In the article there are investigations at a static loading of strength capabilities of a body of the pyrotechnic cartridge which have been made out from an ecological material for different masses of the seeds.
TO THE QUESTION OF 3D MODELING OF GRAINS OF NATURAL DIAMOND POWDERS
Authors:   North-Eastern Federal University named after M.K. Ammosov, Safonova M.N. , Fedotov A.A. ,   North-Eastern Federal University named after M.K. Ammosov, Varlamova L.M. ,   North-Eastern Federal University named after M.K. Ammosov
Published: August 2021

The results of research to establish the most appropriate 3D model of grinding powder's grains of natural diamond are adjusted. Criterion of adequacy is adopted a maximum precision match experimental and calculated values of control characteristics in various 3D models of grain. The quantitative analysis revealed that the closest analogue of the geometric form of spatially-grain grinding powders natural diamond is extrapolation-affine 3D model.
Design and Simulation of an Autonomous Smart Microgrid for Energy Independence
Authors: Ho Hai N. , Bui Tony , Do Hau , Rojas Eliud , Ojeda Omar , Tran Hien , Hoang Tommy , Hernandez Edwin , Nguyen Loc , Le Ha Thu
Published: August 2021

The project designs a microgrid based on downtown community of El Monte city, California. The system main components include a solar PV system, a battery, a diesel generator, an inverter, a control system, and loads. The microgrid design is simulated using MATLAB Simulink. The results show that the microgrid can supply power to its community adequately and independently without relying on a utility power grid. The microgrid is smart as it can operate autonomously thanks to its automatic control system. For various operational scenarios, the microgrid proves to be resilient where it can supply its load demand successfully using its solar system, battery, and diesel generator. The load voltage is kept at satisfactory values of around 1.0 per unit. The power distribution efficiency is around 99%. The results contribute to development of smart microgrids which, in turn, improve the reliability and resiliency of large power grids, as well as provide energy independence to communities
Improving Efficiency in Power Production and Transmission for Offshore Solar Farms using Bifacial Panel Design and HVDC
Authors: Du Hong Bell David , Le Ha Thu
Published: August 2021

As higher demand for power becomes a global concern and offshore power generation becomes more popular, more options should be explored. This study investigates the use of bifacial photovoltaic (PV) panels for offshore solar farms. In addition, it explores the use of HVDC for transmitting the solar power to onshore grid. The results show that bifacial panels have much higher efficiency compared to monofacial panels where the efficiency improvement ranges from 8.5% to 24.8% for a wide range of irradiance (100-1000 W/m2). The newer Voltage Source Converter (VSC) HVDC has high potential for future deployment thanks to its advantages. However, the harmonics from a considered VSC-HVDC system is severe. Some fitters have been designed to mitigate the harmonics. LC low-pass filters are proved to be most effective where they reduce the Total Harmonics Distortion (THD) of the system output voltage from 68.84% to 2.93%. The results are supportive for developing offshore solar farms that provide green energy while preserving land for other purposes.
A STUDY ON THE USE OF PROBABILITY LAWS IN FINITE GROUPS
Authors: Bhadra Mithun
Published: August 2021

In this paper different lows of probability for finite groups were introduced and used for proving two important results. \begin{enumerate} \item For any finite group $G$ of order $pq$, where $p$ and $q$ are prime and $p>q$, there exists exactly one subgroup of order $p$ in $G$. \item If $G$ is a finite group of order $2p$ and $p>2$, then $G$ must have exactly one group of order $p$. \end{enumerate} This paper also investigates the use of probability lows in finite groups problems with some other example and further investigation.
Aproximación desde la Inteligencia Artificial a los comportamientos poco predictivos derivados de modelos cognitivos artificiales
Authors: Vélez-Bedoya Jairo Iván , Castillo-Ossa Luis Fernando , González-Bedia Manuel
Published: August 2021

Antecedentes: Son varias las técnicas que permiten desarrollar modelos de comportamiento artificial poco predictivo, como por ejemplo, las máquinas de estados finitos (FSM) y el uso de arquitecturas cognitivas basadas en la teoría de la mente, para la construcción de agentes cuyo modelo conductual reside sobre un sistema de producciones. Objetivo: Se propuso generar modelos conductuales artificiales para determinar las condiciones en que estos demuestran comportamientos poco predictivos. Metodología: La primera etapa consistió en la elección de plataformas y herramientas. Se escogieron Pogamut, UT2000, SOAR y Java; en la segunda etapa se desarrolló la interfaz de acoplamiento entre el motor de cognición, el lenguaje y el entorno, por último, en la tercera etapa, se efectuaron pruebas con los modelos de comportamiento. Resultados: En el modelo FSM fue posible contrastar los estados y las decisiones que toman los agentes cuando se presentan restricciones en el conjunto de acciones predefinidas en su lógica. Así mismo fue posible el contraste entre producciones SOAR en cuanto a la predictibilidad de las acciones del agente a razón de lo percibido en el entorno. Conclusiones: Las máquinas de estados finitos son un componente importante cuando se quiere inspeccionar el comportamiento reactivo de un agente que persigue un único objetivo. Los agentes reflejos dependen de su lógica para la percepción inmediata de su entorno sin tener en cuenta las decisiones que han tomado o estados por los que ya hayan pasado. Los programas SOAR ajustan la retroalimentación de sus ambientes en ciertos casos.
Risa contagiosa: parámetros acústicos distintivos y apreciación de contagio
Authors: Arévalo-Pachó Guillermo , Cruz Julio Eduardo
Published: August 2021

Antecedentes: Exceptuando la investigación sobre risa contagiosa de Provine (1992), se encuentran pocos estudios sobre este tipo de risa. Objetivo de la investigación: Describir y relacionar los parámetros acústicos de 66 audios de risa contagiosa y la apreciación de contagio que de estos se realizó por parte de 132 universitarios. Metodología: El análisis acústico se basó en el software Praat y la apreciación de contagio se estableció mediante una escala gráfica de calificación. Se propusieron y probaron tres hipótesis sobre la relación entre atributos acústicos, diferencias sexuales y duración de los estímulos de risa y la apreciación de contagio de éstos. Resultados: (a) ningún atributo acústico tomado individualmente permitió discriminar entre los estímulos femeninos y masculinos más y menos contagiosos; (b) los predictores acústicos de apreciación de contagio incluyeron la duración de los periodos de risa y los formantes F1 y F2; (c) no se observaron efectos principales ni de interacción entre el sexo del emisor de la risa contagiosa y el sexo del receptor de la misma y (d) los estímulos de risa con una duración entre 8 y 11 segundos generaron las apreciaciones de contagio más altas. Los resultados se discutieron con base en teorías y resultados empíricos sobre el tema. Conclusiones: Se concluye que esta risa tiene características acústicas y de apreciación distintivas, algunas de las cuales están relacionadas, aunque comparte algunos atributos con la risa espontánea.
Trastorno por estrés postraumático y epigenética. Metilaciones en genes asociados al estrés
Authors: Castaño-Loaiza Laura Ximena , Gallego-Ospina Carol Dayana , García-Aguirre Jhonny Fernando , Orrego-Cardozo Mary
Published: August 2021

Antecedentes: El trastorno por estrés postraumático (TEPT) es un desorden psiquiátrico relacionado con estrés y ansiedad producido por un evento traumático. Es de origen multifactorial y destacan factores genéticos, epigenéticos y ambientales. Objetivo: Presentar una revisión de literatura que muestre la relación entre las metilaciones en genes de la vía de los glucocorticoides y el desarrollo del TEPT. Metodología: La búsqueda de literatura se realizó en las bases de datos Web of Science (WoS), Scopus y PubMed con la ecuación de búsqueda: “PTSD” and “glucocorticoid” and “epigenetic”, entre 2000 y 2020. Resultados: Se analizaron 12 artículos de investigación que repotaron la relación entre los genes: NR3C1, FKBP5, GILZ, las metilaciones asociadas y el desarrollo de TEPT. Se encontró que los niveles de metilación de estos genes están relacionados con el desarrollo de TEPT en personas que sufrieron abuso infantil, en víctimas que padecieron traumas de guerra (genocidio, combate, holocausto) y en sus hijos; asociados a cambios estructurales en áreas cerebrales y la respuesta al tratamiento. Conclusiones: Las metilaciones en los genes involucrados en la vía de los glucocorticoides están implicados en el riesgo de desarrollar TEPT. Se evidencia heterogeneidad de resultados en la relación de los niveles de metilación y el riesgo de padecer el trastorno; en el tipo de población y en los tipos de trauma. Los niveles de metilación en los genes revisados podrían ser usados como biomarcadores relacionados con factores como: herencia, tratamiento y susceptibilidad de padecer TEPT ante diferentes traumas y ser evaluados en futuras investigaciones en distintas poblaciones.
Revisión al estudio del cambio conceptual en el aprendizaje de la química
Authors: Cadavid-Álzate Valentina , Lara-Escobar Rubén Dario
Published: August 2021

Antecedentes: Dentro del cambio conceptual, existen diferentes perspectivas teóricas desde las cuales se estudia la naturaleza, las características y los mecanismos de cambio de las ideas de los estudiantes. Conocer estas ideas es fundamental antes de desarrollar los procesos de enseñanza. Objetivo: Conocer los autores y artículos más citados en el área del cambio conceptual y aprendizaje de la química, al igual que las revistas en las que se publican estos artículos. Método: Se realizó la búsqueda en las bases de datos Web of Science y Scopus entre los años 2009 y 2019, teniendo como criterios de inclusión: el área de conocimiento (estudios en educación), tipo de documento artículo de investigación publicados en revistas especializadas, en idioma inglés, español y portugués. Resultados: después de aplicar los criterios de inclusión finalmente se analizan 12 artículos a través del paquete estadístico bilbiometrix en el software R. Conclusión: es evidente el predominio de los enfoques unidimensionales en el estudio del cambio conceptual en química. En estos estudios, prevalecen los enfoques cuantitativos y mixtos. Por otra parte, hay una creciente tendencia del estudio de las ideas de los estudiantes, desde una miranda multidimensional en la que las emociones, la interacción social y la autorregulación inciden en los procesos de cambio conceptual.
POSTPARTUM 'S KNOWLEDGE ABOUT BREAST CARE AS EXCLUSIVE EFFORTS AT RS ST ELISABETH, BATAM CITY
Authors: Miguna Sarita , Alâ€™amri Magfirah
Published: August 2021

Background : The puerperium is a recovery period after the birth process begins at the birth of the placenta, and ends when the reproductive organs return to normal, such as in a woman who is not pregnant. An effort is needed to increase milk production during the puerperium, one of which is breast care so that the rights of babies to get breast milk from their mothers are fulfilled. The purpose of this study was to determine the knowledge of postpartum mothers about breast care. Method : The research method used is descriptive, conducted at the hospital. ST Elisabeth Batam City, the research was conducted for 6 months, the population in this study were all postpartum mothers who were in the postpartum room of Elisabeth Hospital Batam City when the research took place, namely as many as 33 people, the sampling technique was carried out by using total sampling technique with research instruments using a questionnaire. Result : The results showed that the majority of good knowledge as many as 24 people (72.7%) and less knowledgeable as many as 9 people (27.3%). conclusion : The conclusion of this study most of the knowledge of postpartum mothers about breast care is Good. Suggestions for respondents to apply breast care properly in order to be able to provide breastfeeding exclusively
YOUTH KNOWLEDGE ABOUT THE GENERATION PLANNING PROGRAM AND ATTITUDE OF YOUTH IN MATURITY AGE OF MARRIAGE AT SMA NEGERI 4 BATAM
Authors: Perdoman Acholder Tahi , Fitriana Dewi
Published: August 2021

Background : Generation Planning is a program developed in the context of preparing and planning family life for adolescents. One of the main focuses in this program is the maturity of marriage age for adolescents. The purpose of this study was to describe the knowledge of adolescents about the Generation Planning program and the attitudes of adolescents in the maturity of the marital age at SMA Negeri 4 Batam. Method : This study used a descriptive research design. The length of the research was 6 months with a population of all students of class X and XI SMA N 4 Batam as many as 737 students, the sampling was systematic random sampling with a sample size of 88 respondents. , Result : as many as 53 respondents (60.2%) and good as many as 35 respondents (39.8%). Frequency distribution of the majority of adolescents' attitudes have positive attitudes as many as 63 respondents (71.6%) and those who have negative attitudes are 25 respondents (28.4%) conclusion : Adolescent knowledge about the Planning Generation program at SMAN 4 Batam is the majority of the knowledge is Less as many as 53 respondents (60%) The attitude of adolescents in the Maturity of the Marriage Age at SMAN 4 Batam is that the majority are positive as many as 63 respondents (71%)
OTHER'S MOTIVATION TO BRING TODDLERS TO POSYANDU TIBAN INDAH VILLAGE, SEKUPANG HEALTH CENTER WORK AREA
Authors: Al'amri Magfirah , Miguna Sarita
Published: August 2021

Background :Toddlers are a period of rapid body and brain growth in achieving optimal functions. Posyandu is a community health facility managed independently by the community. The research objective was to determine whether there was a relationship between motivation and the behavior of mothers bringing toddlers to Posyandu in the Tiban Indah Village, the working area of the Sekupang Health Center, Batam City. Toddlers are a period of rapid body and brain growth in achieving optimal functions. Posyandu is a community health facility managed independently by the community. The research objective was to determine whether the motivation of mothers to bring toddlers to Posyandu in the Tiban Indah Village, the Working Area of the Sekupang Health Center, Batam City in 2017. Method :The design of this research is a descriptive study. The population in this study were all households with toddlers aged 1-5 years as many as 1,420 children under five, with a total sample of 312 respondents, using purposive sampling technique. The research was conducted in the Sekupang Health Center, Batam City. Result : It can be seen from 312 respondents, it can be seen that as many as 130 respondents (41.7%) have high motivation, and 182 respondents (58.3%) have low motivation to visit Posyandu in Tiban Indah Village, Sekupang Health Center, Batam
Perlindungan Hukum Terhadap Pengguna Jasa Perkeretaapian Terkait Dengan Pelecehan Seksual yang Terjadi di Atas Kereta Api Dikaji Oleh Undang-Undang Nomor 8 Tahun 1999 Tentang Perlindungan Konsumen (Studi Kasus PT. Kereta Api Indonesia)
Authors: Lauwtania Fellycia
Published: August 2021

Terdapat berbagai sarana transportasi umum yang banyak disediakan oleh pemerintah di Indonesia, salah satunya adalah transportasi yang disediakan oleh PT. KAI (Kereta Api Indonesia). Transportasi yang disediakan oleh PT. KAI ini berupa transportasi yang berupa kereta lokomotif yang tersebar di beberapa pulau dan menghubungkan daerah-daerah yang membutuhkan jarak tempuh dengan waktu yang cukup lama termasuk di antaranya Pulau Jawa. Karena perjalanan yang dilakukan membutuhkan waktu yang tidak sebentar, seharusnya PT. KAI dapat memberikan kenyamanan dan keamanan bagi konsumen terutama perlindungan hukum. Tetapi pada kenyataannya, perlindungan hukum bagi konsumen belum sepenuhnya terpenuhi seperti beberapa kasus yang telah terjadi, yaitu masih adanya pelecehan seksual yang terdapat di dalam kereta api. Penelitian ini bertujuan untuk mengetahui bagaimana seharusnya tindakan PT. KAI dalam memberikan perlindungan hukum serta tanggung jawab terhadap kasus pelecehan seksual yang terjadi di kereta api. Penelitian ini menggunakan metode yuridis normatif, karena didasarkan pada pendekatan peraturan perundang-undangan. Data yang digunakan dalam penelitian ini adalah data sekunder dan undang-undang lain sebagai literatur.
Perlindungan Data Konsumen Pengguna Fintech Terhadap Penyalahgunaan Data Baik Sengaja Maupun Tidak Sengaja Terhadap Serangan Hacker dan Malware (Studi Pada Lembaga Perlindungan Konsumen di Lampung)
Authors: Negara Kurniawan Suya , Rusli Tami , Hapsari Recca Ayu
Published: August 2021

Perlindungan konsumen yaitu semua upaya yang menjamin keberadaan kepastian hukum dan untuk memberi perlindungan bagi konsumen. Penelitian ini guna untuk mengetahui perlindungan dan pertanggungjawaban hukum terhadap penyalahgunaan data konsumen pengguna fintech terhadap serangan hacker dan malware. Tata cara riset ini dilakukan dengan menggunakan pendekatan yuridis normatif yuridis empiris dengan data sekunder serta data primer. Analisis yang digunakan adalah analisis kualitatif. Hasil dari penelitian ini disimpulkan bahwa perlindungan hukum terhadap penyalahgunaan data konsumen fintech saat ini diatur dalam PP No. 71 Tahun 2019 tentang Penyelenggaraan Sistem Transaksi Elektronik, dalam Pasal 14 ayat (1) tentang Penyelenggaraan Sistem Elektronik (PSE). Pertanggungjawaban terhadap penyalahgunaan data pribadi konsumen fintech adalah para pihak penyelenggara berhak bertanggungjawab atas penyalahgunaan data konsumen fintech, menurut beberapa peraturan pihak penyelenggara dikenakan sanksi yaitu, berupa teguran tertulis denda administratif seperti: penghentian sementara, pemutusan akses, dan dikeluarkan dari daftar.
INTERSTITIAL PULMONARY FIBROSIS ASSOCIATED CONNECTIVE TISSUE DISEASES – CLINICAL AND IMAGING ASPECTS
Authors:   Department of Internal Medicine and Rheumatology, Sf. Maria Hospital, Bucharest, Gheorghe Madalina , Bojinca Violeta Claudia ,   Department of Internal Medicine and Rheumatology, Sf. Maria Hospital, Bucharest,   Carol Davila University of Medicine and Pharmacy, Bucharest, Ionescu Ruxandra ,   Department of Internal Medicine and Rheumatology, Sf. Maria Hospital, Bucharest,   Carol Davila University of Medicine and Pharmacy, Bucharest
Published: August 2021

The lung is a common site of complications in systemic connective tissue diseases (CTD), and its involvement can present in several ways. Although it is generally thought that interstitial lung disease develops later on in CTD, it is often the initial presentation (“lung dominant” CTD). Interstitial lung disease (ILD) can be present in most types of CTD, including rheumatoid arthritis, systemic sclerosis, systemic lupus erythematosus, polymyositis or dermatomyositis, Sjögren’s syndrome and mixed connective tissue disease. Despite similarities in clinical and pathologic presentation, the prognosis and treatment of CTD associated ILD (CTD-ILD) can differ greatly from that of other forms of ILD. Interstitial lung disease must be detected early in the course of collagen disorders by performing high-resolution computed tomography and pulmonary function tests. The pattern described on HRCT is predictive for treatment response and disease progression. Immunosuppression is the mainstay of treatment for ILD, although data from randomized controlled trials (RCTs) to support specific treatments are lacking. The management of patients with CTD-associated ILD is optimized by multidisciplinary collaboration.
ASSOCIATION BETWEEN PERIODONTAL DISEASE AND OSTEOPOROSIS
Authors:   Physiology Department, Faculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Piperea-Sianu Dan , Ceau Adela M. ,   Politehnica University of Bucharest, Carsote Mara ,   Endocrinology Department, Faculty of General Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Croitoru Alexandru G. ,   Physiopathology and Immunology Department, Faculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Cristea Stefan ,   Orthopaedics and Traumatology Department, Faculty of General Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest
Published: August 2021

Osteoporosis and periodontal disease (PD) are two chronic diseases, characterized by bone loss, with systemic or local impact (alveolar bone). Both pathologies have a progressive evolution, leading to systemic bone loss in the case of osteoporosis and bone lysis localized in the alveolar bone in the case of periodontal disease. The present paper presents recent data from the literature on the association between periodontal disease and osteoporosis, on the role of cytokines in the bone resorption-apposition imbalance, and on how periodontal disease causes changes in serum levels of cytokines, leading to disorders in the systemic bone formation. We also found it useful, especially for rheumatologists, to outline the extent to which periodontal disease can create a systemic context favorable to the development of osteoporosis.
CLINICAL SIGNIFICANCE OF ANTI-RO52/TRIM21 ANTIBODIES IN SYSTEMIC AUTOIMMUNE RHEUMATIC DISORDERS: PRELIMINARY RESULTS
Authors:   Grigore T. Popa University of Medicine and Pharmacy, Iasi, Pomirleanu Cristina ,   Rheumatology 2 Department, Clinical Rehabilitation Hospital, Iasi, Paiu Raluca ,   Rheumatology 2 Department, Clinical Rehabilitation Hospital, Iasi, Strugariu Georgiana ,   Rheumatology 2 Department, Clinical Rehabilitation Hospital, Iasi, Petrariu Luiza ,   Rheumatology 2 Department, Clinical Rehabilitation Hospital, Iasi, Ancuta Codrina ,   Grigore T. Popa University of Medicine and Pharmacy, Iasi,   Rheumatology 2 Department, Clinical Rehabilitation Hospital, Iasi
Published: August 2021

Although antibodies targeting Ro52 protein/TRIM21 are commonly detected in systemic autoimmune rheumatic disorders (SARDs), their clinical significance and pathobiologic role remains incompletely understood. Objectives. We aimed to define clinical relevance and immunological associations of anti-Ro52/TRIM21 positivity in a cohort of patients with SARDs. Methods. We retrospectively reviewed medical records of 97 consecutive SARDs who attended at least once our Rheumatology Department between March 2016 and June 2017. Clinical manifestations, rheumatoid factor (RF) (Latex and Waalter-Rose tests), antinuclear antibodies (ANA>1:100, immunofluorescence assays) as well as detailed ANA profile (nRNP/Sm, Sm, SS-A/Ro, Ro52/TRIM21, SS-B/La, Scl-70, PM/Scl, Jo-1, CENP-B, PCNA, dsDNA, nucleosome, histone, P-ribosomal protein, AMA-M2, DFS70) (line immunoblot assay) were systematically evaluated. Statistical analysis was performed in SPSS19.0, assuming significance for p<0.05; the chi-squared test was applied to determine the association between anti-Ro52/TRIM21 status and clinical manifestations of SARDs. Results. Only 27 patients (23.7%) had anti-Ro52/TRIM21 positive disease and were further analyzed. Isolated anti-Ro52/TRIM21 were detected in 7/27 (25.9 %) cases, while the majority had dual anti-Ro52/TRIM21 positivity and anti-Ro (n=7/20; 35%), anti-dsDNA (n=3/20, 15%), anti-Jo1 (n=3/20, 15%), anti-centromere B (n=2/20; 10%), anti-Scl70 (n=2/20; 10%), anti-RNP/Sm (n=2/20, 10%), anti-Pm/Scl (n=1/20, 5%), and RF (n=13; 65%). Patients were classified as Sjögren’s syndrome (n=7/27, 25.9%), myositis (n=3/27, 11.1%), systemic lupus erythematosus (n=3/27, 11.1%), systemic sclerosis (n=4/27,15.2%), mixed (n=3/27, 11.1%) or undifferentiated connective tissue disease (n=7/27, 25.9%). More than half of anti-Ro52/TRIM21 positive patients presented with interstitial lung fibrosis (18/27, 66.6%), insolated (33.3%) or in association with anti-Jo1 (33.3%). Conclusions. Anti-Ro52/TRIM21 antibodies should be systematically evaluated in patients with SARDs, as anti-Ro52 positivity (either isolated or in combination with different other ANA specificities) may be associated with definite clinical features. Anti-Ro52/TRIM21 may be useful in identifying a subgroup of patients at risk for developing certain symptoms (particularly interstitial lung disease) of SARDs, with specific therapeutic outcomes.
TREATMENT OF UVEITIS ASSOCIATED WITH SYSTEMIC AUTOIMMUNE DISEASES IN ADULTS: A CONCISE OVERVIEW
Authors:   Iuliu Hatieganu University of Medicine and Pharmacy, Rheumatology Clinic, Cluj-Napoca, Muntean Laura , Rednic Simona ,   Iuliu Hatieganu University of Medicine and Pharmacy, Rheumatology Clinic, Cluj-Napoca
Published: August 2021

Uveitis represents a heterogenous group of inflammatory ocular diseases which may cause vision loss. Association of uveitis with arthritis may occur in many systemic autoimmune diseases, including spondyloarthritis, juvenile idiopathic arthritis, Behҫet’s disease and sarcoidosis. Recent advances in the field of autoimmune diseases have provided new insights and developments of diverse therapies for noninfectious uveitis. However, the optimal treatment strategy for patients with uveitis remains to be defined. Topical and/or systemic corticosteroids are the first-line therapy of autoimmune uveitis, but relapses are frequent after treatment cessation. Chronic use of corticosteroids is associated with significant systemic and ocular side effects. Many patients require treatment with conventional immunomodulatory drugs and/or biological agents in order to maintain long-term remission for both ocular inflammation and systemic disease. Treatment of uveitis should be individualized based on several factors, including the location of ocular inflammation, the inflammation severity, the impact on visual function and quality of life, the type of systemic autoimmune disease, and comorbidities. This paper provides a concise overview of the current treatment modalities and strategies available for adult patients with uveitis associated with systemic autoimmune diseases.
Performance-based assessment: Self-efficacy, decision-making, and problem-solving skills in learning science
Authors: Villarta Yvette M. , Atibula Levi T. , Gagani Flordeliza S.
Published: August 2021

Performance-based assessment is a purposive-oriented assessment activity in revealing student understanding of unwrapped concepts, skills, and big ideas. This study aimed to determine the effects of performance task assessment on the students' self–efficacy, problem–solving, and decision–making skills in learning science that used the quantitative and correlation methods of research. There were 35 Grade 9 students of the University of San Carlos, Basic Education Department – South Campus in science class as respondents of the study. The assessment was given after the engagement session of the instructional plan to be accomplished after the transfer task session and evaluated using specific rubrics. A modified Albert Bandura's Instrument was used to measure self–efficacy and Mind Tool: Essential Skill for Excellent Career questionnaires for the problem–solving and decision–making skills of the students in learning science. The study's findings indicated that the Performance Assessment developed students' self–efficacy in learning science and had a significant impact on how students think, feel, and behave in the process of learning. Moreover, the assessment conveyed positive influence in developing students' problem–solving and decision–making skills. This assessment encouraged students to apply the scientific processes in evaluating the identified options before deciding the problem's solution.
Pre- and Post-Natal Endotoxin Exposures: Effects on Leucocyte Ratios and Levels of IL-1β, TNF-, Gonadotropins and Corticosterone in Female Rats
Authors: YILDIRIM Hilal , YILDIZ Sedat , ÖZGÖÇER Tuba
Published: August 2021

Aim: The aim of this study is to investigate the long-term effects of prenatal and postnatal endotoxin exposure on hematological parameters, blood cytokines (TNF-α, IL-1β), gonadotropins and corticosterone levels in female rats. Material and Method: Pregnant rats were injected intraperitoneally sterile saline (SF) or endotoxin (LPS) on days 17-18 of pregnancy. Following birth, female pups were subdivided into two groups and injected either sterile saline (SF, n=17) or endotoxin (LPS, n=17) on postnatal day 60 and four experimental groups were formed (SF+SF, SF+LPS, LPS+SF and LPS+LPS). Blood samples were taken 4 hours after final injection. Plasma levels of IL-1β, TNF-α, corticosteron, LH, FSH and blood leucocyte ratios were evaluated.Results: Neutrophil % ratio was higher but lymphocyte % ratio was lower in SF+LPS, LPS+SF and LPS+LPS groups than SF+SF group. Corticosterone, LH and FSH levels were not different between the groups but TNF-α level of LPS+LPS groups was higher than SF+SF and LPS+SF groups. IL-1β level of SF+LPS group was higher than SF+SF and LPS+SF groups. Conclusion: The results suggest that prenatal and post-pubertal endotoxin exposure programs cytokine level neutrophil and lymphocyte percentages without affecting hypothalamo-pituitary-adrenal and –gonadal axes.
The Effect of Blood Groups on Infection and Prognosis of SARS-CoV-2
Authors: ASLANER Humeyra , GÖKÇEK Mebrure Beyza , BENLİ Ali Ramazan , BAYDEMİR Recep , GÜVEN Zeynep , AKYOL Gülşah , KAYNAR Leylagül
Published: August 2021

Aim: This study aimed to investigate the effect of blood groups on the risk and prognosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the infected/source cases and contact individuals. Material and Method: This study was designed as a descriptive and retrospective study. The individuals who were in contact with the SARS-CoV-2main/source cases and followed at home were included in the study.The distribution of the participants according to their blood groups was assessed. Patients were divided into three groups as group 1 including source/main cases, group 2 including SARS-CoV-2contacts who were living in the same house with the source case and followed up, and group 3 including contacts who were followed up in the same house but did not develop SARS-CoV-2 during the follow-up.Results: While the rate of Non-O blood group was the highest (n=365, 39.4%) in group 2the rate of O blood group was the highest (n=190, 42.8%) in group 3 (p:0.028). While the rate of Rh positive blood group was high in group 1 that of Rh negative blood group was higher in group 3 (p:0.000). For other variables, the presence of a chronic disease was more in group 1 (p:0.000). Rh (+) blood group (OR:0.464, p:0.010, %95 Cl: 0.306 ~ 0.703) was among the factors affecting the development of the infection. Conclusion: Patients infected with SARS-CoV-2 mostly had A, Non-O blood group and Rh positivity. Having Rh (+) blood group may have increased the rate of infection development in high-risk household contacts. After patients in this blood group were detected as contacts a closer follow-up may be necessary to decrease morbidity.
Evaluation of Routine Coagulation Testing Requirements in Patients with Severe Epistaxis
Authors: ÇEKMEN Bora , BOZAN Öner , ATİŞ Şeref Emre , ÜNVER Sevilay Sema , KOKULU Kamil , KALKAN Asım
Published: August 2021

Aim: There are studies about coagulation parameters are not required in the management of epistaxis. The aim of the present study was to investigate whether or not coagulation tests are required and its relationship with medications in severe epistaxis cases that require intervention. Material and Method: The patients above 16 years who had presented to emergency department due to epistaxis, who had undergone anterior/posterior nasal packing or electro-cautery to the nasal mucosa were included the study. The demographic characteristics, blood count, coagulation test, anti-platelet and anti-coagulant medications, the procedures carried out for stopping bleeding, whether reversal treatment or blood transfusion was needed were recorded. Results: A total of 469 patients, it was found that coagulation parameters had been tested in 141(30.2%). While PT, aPTT and INR values of the anti-coagulant using patients were significantly higher(p<0.001, p=0.003, p<0.001, respectively), the platelet and hemoglobin values were not found to be associated with anti-platelet drug and anti-coagulant use(p=0.304, p=0.098, respectively). The patients were allocated to two groups as those any parameter of whom was impaired or not. While a significant difference was found between the groups with regard to hemoglobin values(p=0.006), no patients were determined to need reversal treatment or hemoglobin replacement.Conclusion: Routine coagulation testing is not required for patients who have epistaxis that cannot be stopped with conservative methods and who are using anti-platelet drugs as it does not lead to a difference in treatment. Coagulation tests may not be performed in patients who use anti-coagulants based on the results.
Acral Melanoma Presenting with Lung Invasion and a Giant Inguinal Mass
Authors: OZKAN SEVENCAN Nurhayat , YANIK Ahmet Mert , BAYKAL Özlem , JAFAROV Yusif , AKÇA İlhan Asude , GÜL Duygu , BAT Erol , TANGUR Onur , AKBAL Adem , SARIKAYA Ayse Rana , KAYHAN Burçak
Published: August 2021

Although malignant melanoma is a rare type of skin cancer, it accounts for most skin cancer-related deaths. Foot lesions may be ignored by both patients and clinicians and could therefore lead to advanced disease. An acral melanoma may also be confused with a pressure ulcer and result in a late diagnosis. The need to perform a skin biopsy should therefore be considered when dealing with protracted wounds. In this report, we present the case of an 84-year-old female patient with malignant melanoma, which was diagnosed late, recurred in the same area following surgery, and caused lung metastasis and a giant inguinal mass.