bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 2 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses
Authors: Shono Yusuke , Tuckett Andrea Z. , Liou Hsiou-Chi , Doubrovina Ekaterina , Derenzini Enrico , Ouk Samedy , Tsai Jennifer J. , Smith Odette M. , Levy Emily R. , Kreines Fabiana M. , Ziegler Carly G.K. , Scallion Mary I. , Doubrovin Mikhail , Heller Glenn , Younes Anas , O'Reilly Richard J. , van den Brink Marcel R.M. , Zakrzewski Johannes L.
Published: April 2023

IT-901 is a more potent NF-κB inhibitor than IT-603.
Supplementary Figure 10 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses
Authors: Shono Yusuke , Tuckett Andrea Z. , Liou Hsiou-Chi , Doubrovina Ekaterina , Derenzini Enrico , Ouk Samedy , Tsai Jennifer J. , Smith Odette M. , Levy Emily R. , Kreines Fabiana M. , Ziegler Carly G.K. , Scallion Mary I. , Doubrovin Mikhail , Heller Glenn , Younes Anas , O'Reilly Richard J. , van den Brink Marcel R.M. , Zakrzewski Johannes L.
Published: April 2023

Several NF-κB subunits are constitutively active in activated B-like DLBCL cell lines.
Supplementary Table S7 from Quantitative Phosphotyrosine Profiling of Patient-Derived Xenografts Identifies Therapeutic Targets in Pediatric Leukemia
Authors: Dolai Sibasish , Sia Keith C.S. , Robbins Alissa K. , Zhong Ling , Heatley Sue L. , Vincent Tiffaney L. , Hochgräfe Falko , Sutton Rosemary , Kurmasheva Raushan T. , Revesz Tamas , White Deborah L. , Houghton Peter J. , Smith Malcolm A. , Teachey David T. , Daly Roger J. , Raftery Mark J. , Lock Richard B.
Published: April 2023

Enriched Class I tyrosine phosphorylated sites of TKs in ALL-77 PDX
Supplementary Methods from MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin
Authors: O'Brien Rosemary , Tran Sieu L. , Maritz Michelle F. , Liu Bing , Kong Cheng Fei , Purgato Stefania , Yang Chen , Murray Jayne , Russell Amanda J. , Flemming Claudia L. , von Jonquieres Georg , Pickett Hilda A. , London Wendy B. , Haber Michelle , Gunaratne Preethi H. , Norris Murray D. , Perini Giovanni , Fletcher Jamie I. , MacKenzie Karen L.
Published: April 2023

Text file containing detailed methods.
Supplemental Figures S1-S4 from Autophagy Differentially Regulates Distinct Breast Cancer Stem-like Cells in Murine Models via EGFR/Stat3 and Tgfβ/Smad Signaling
Authors: Yeo Syn Kok , Wen Jian , Chen Song , Guan Jun-Lin
Published: April 2023

Gating strategy for analysis and isolation of CSC populations (S1); Tumors that arise from transplanted sorted populations recapitulate features of parental tumors (S2); Tumors that arise from transplanted sorted populations display Stat3 and Smad2 activation (S3); Inhibition of autophagy after FIP200 deletion (S4).
Supplementary Table 2 from Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer
Authors: Dou Qianhui , Chen Hai-Ning , Wang Kui , Yuan Kefei , Lei Yunlong , Li Kai , Lan Jiang , Chen Yan , Huang Zhao , Xie Na , Zhang Lu , Xiang Rong , Nice Edouard C. , Wei Yuquan , Huang Canhua
Published: April 2023

Supplementary Table 2
Supplementary Materials and Methods from Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer
Authors: Dou Qianhui , Chen Hai-Ning , Wang Kui , Yuan Kefei , Lei Yunlong , Li Kai , Lan Jiang , Chen Yan , Huang Zhao , Xie Na , Zhang Lu , Xiang Rong , Nice Edouard C. , Wei Yuquan , Huang Canhua
Published: April 2023

Supplementary Materials and Methods
Supplementary Figure S7-9 from Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer
Authors: Dou Qianhui , Chen Hai-Ning , Wang Kui , Yuan Kefei , Lei Yunlong , Li Kai , Lan Jiang , Chen Yan , Huang Zhao , Xie Na , Zhang Lu , Xiang Rong , Nice Edouard C. , Wei Yuquan , Huang Canhua
Published: April 2023

Supplementary Figure S7-9
Supplemental Table1 from Aberrant Activation of Notch Signaling Inhibits PROX1 Activity to Enhance the Malignant Behavior of Thyroid Cancer Cells
Authors: Choi Dongwon , Ramu Swapnika , Park Eunkyung , Jung Eunson , Yang Sara , Jung Wonhyeuk , Choi Inho , Lee Sunju , Kim Kyu Eui , Seong Young Jin , Hong Mingu , Daghlian George , Kim Daniel , Shin Eugene , Seo Jung In , Khatchadourian Vicken , Zou Mengchen , Li Wei , De Filippo Roger , Kokorowski Paul , Chang Andy , Kim Steve , Bertoni Ana , Furlanetto Tania Weber , Shin Sung , Li Meng , Chen Yibu , Wong Alex , Koh Chester , Geliebter Jan , Hong Young-Kwon
Published: April 2023

A concise summary of the publically available transcriptome data sets that were used to generate Figure 1 in the main text.
Supplementary Tables S1-S3 from Histone Deacetylase Inhibition in Prostate Cancer Triggers miR-320–Mediated Suppression of the Androgen Receptor
Authors: Sato Shinya , Katsushima Keisuke , Shinjo Keiko , Hatanaka Akira , Ohka Fumiharu , Suzuki Shugo , Naiki-Ito Aya , Soga Norihito , Takahashi Satoru , Kondo Yutaka
Published: April 2023

Supplementary Table S1. Background of Prostate Cancer Patients. Supplementary Table S2. List of the primers. Supplementary Table S3. 91 miRNAs upregulated in at least 1 of 3 cell lines.
Supplementary Figures S1-7 and Tables S1-2 from Urokinase Receptor Promotes Skin Tumor Formation by Preventing Epithelial Cell Activation of Notch1
Authors: Mazzieri Roberta , Pietrogrande Giovanni , Gerasi Laura , Gandelli Alessandro , Colombo Piergiuseppe , Moi Davide , Brombin Chiara , Ambrosi Alessandro , Danese Silvio , Mignatti Paolo , Blasi Francesco , D'Alessio Silvia
Published: April 2023

This file include Supplementary Figures S1-7 and Tables S1-2. Figure S1. Inflammation and neo-angiogenesis are not impaired in TPA-treated uPAR-/- skin. Figure S2. Distinct stages of hair cycling in uPAR+/+ and uPAR-/- littermates. Figure S3. FACS isolation of K14-GFP-actin/uPAR+/+ and K14-GFP-actin/uPAR-/- mouse epidermal cell sub-populations. Figure S4. Long-term growth of FACS-sorted epidermal cell subpopulations. Figure S5. Determination of "differentiated" and "proliferating" human Keratoacanthomas. Figure S6. uPAR promotes skin epithelial cell response to a proliferative stimulus by TACE-dependent Notch1 activation. Figure S7. uPAR sequesters the shedding activity of TACE in lipid rafts, thus inhibiting differentiation of primary keratinocytes. Table S1. Estimates, corresponding standard errors and P values of the fitted zero-inflated regression models. Table S2. Number of uPAR+/+ and uPAR-/- hair follicles/section in the telogen, anagen, and catagen stages.
Supplemental Methods and Supplemental Table from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
Authors: Camp Nicola J. , Lin Wei-Yu , Bigelow Alex , Burghel George J. , Mosbruger Timothy L. , Parry Marina A. , Waller Rosalie G. , Rigas Sushilaben H. , Tai Pei-Yi , Berrett Kristofer , Rajamanickam Venkatesh , Cosby Rachel , Brock Ian W. , Jones Brandt , Connley Dan , Sargent Robert , Wang Guoying , Factor Rachel E. , Bernard Philip S. , Cannon-Albright Lisa , Knight Stacey , Abo Ryan , Werner Theresa L. , Reed Malcolm W.R. , Gertz Jason , Cox Angela
Published: April 2023

Equations to calculate sample size in a homozygous discordant design. Supplemental Table: Sample size requirements (n in each group)
SupplementaryFigure 1 from Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation
Authors: Spratt Daniel E. , Evans Michael J. , Davis Brian J. , Doran Michael G. , Lee Man Xia , Shah Neel , Wongvipat John , Carnazza Kathryn E. , Klee George G. , Polkinghorn William , Tindall Donald J. , Lewis Jason S. , Sawyers Charles L.
Published: April 2023

Supplementary Figure 1. In vitro experiments demonstrating increase AR protein level post-radiotherapy; A) Nuclear AR staining, B) 18F-FDHT uptake. C) Isodose distribution of multibeam animal EBRT.
Supplementary Figure 3 from Germinal Centers Determine the Prognostic Relevance of Tertiary Lymphoid Structures and Are Impaired by Corticosteroids in Lung Squamous Cell Carcinoma
Authors: Siliņa Karīna , Soltermann Alex , Attar Farkhondeh Movahedian , Casanova Ruben , Uckeley Zina M. , Thut Helen , Wandres Muriel , Isajevs Sergejs , Cheng Phil , Curioni-Fontecedro Alessandra , Foukas Periklis , Levesque Mitchell P. , Moch Holger , Linē Aija , van den Broek Maries
Published: April 2023

Immunohistochemistry images depicting the cell types expressing CCL21, CXCL13, CXCL12 and PD-L1 in the lungs.
Supplementary Table 1 from Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability
Authors: Li Xiangchun , Wu William K.K. , Xing Rui , Wong Sunny H. , Liu Yuexin , Fang Xiaodong , Zhang Yanlin , Wang Mengyao , Wang Jiaqian , Li Lin , Zhou Yong , Tang Senwei , Peng Shaoliang , Qiu Kunlong , Chen Longyun , Chen Kexin , Yang Huanming , Zhang Wei , Chan Matthew T.V. , Lu Youyong , Sung Joseph J.Y. , Yu Jun
Published: April 2023

Supplementary Table 1: Published publications and cohorts
Supplementary Figure Legends from Eritoran Suppresses Colon Cancer by Altering a Functional Balance in Toll-like Receptors That Bind Lipopolysaccharide
Authors: Kuo Wei-Ting , Lee Tsung-Chun , Yu Linda Chia-Hui
Published: April 2023

Legends for supplementary figures and videos.
Supplementary Figure 1 from Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability
Authors: Li Xiangchun , Wu William K.K. , Xing Rui , Wong Sunny H. , Liu Yuexin , Fang Xiaodong , Zhang Yanlin , Wang Mengyao , Wang Jiaqian , Li Lin , Zhou Yong , Tang Senwei , Peng Shaoliang , Qiu Kunlong , Chen Longyun , Chen Kexin , Yang Huanming , Zhang Wei , Chan Matthew T.V. , Lu Youyong , Sung Joseph J.Y. , Yu Jun
Published: April 2023

Fig. S1: Optimization of number of molecular subtypes and assessment of batch effects.
Supplemental Figure 5 TRIM3 effects on Importinβ1 nuclear localization and NICD binding. from Drosophila Brat and Human Ortholog TRIM3 Maintain Stem Cell Equilibrium and Suppress Brain Tumorigenesis by Attenuating Notch Nuclear Transport
Authors: Mukherjee Subhas , Tucker-Burden Carol , Zhang Changming , Moberg Kenneth , Read Renee , Hadjipanayis Costas , Brat Daniel J.
Published: April 2023

(A,B,C,D) N08-74 VC and 13113 VC both show more Importinβ1 nuclear localization than TRIM3 expressing N08-74 and 13113 cells, respectively. (E,F,G,H) NICD binds with Importin beta to a greater extent in TRIM3 null N08-74 and 13113 as compared to TRIM3 expressing N08-74 and 13113 cells, respectively. Scale bar: 5um.
Supplemental Figure 2 Brain tumor in adult Drosophila reduces lifespan and causes motor defect. from Drosophila Brat and Human Ortholog TRIM3 Maintain Stem Cell Equilibrium and Suppress Brain Tumorigenesis by Attenuating Notch Nuclear Transport
Authors: Mukherjee Subhas , Tucker-Burden Carol , Zhang Changming , Moberg Kenneth , Read Renee , Hadjipanayis Costas , Brat Daniel J.
Published: April 2023

(A) Kaplan-Meyer survival analysis of adult female Drosophila shows that brat-RNAi leads to a reduction in mean life expectancy as compared to controls. (B) Adult flies with brain tumor also have reduced negative geotaxis, a test of motor function. (C,D,E,F) PH3 staining in whole brain shows the adult brat-RNAi brain with actively dividing cells, whereas normal brain does not contain dividing cells. N = 20. P<0.0001. (G, H) Low magnification image of control and brat-RNAi brain. Repo-GFP shows significantly higher number tumor-like cells (marked with Tub-cherry) expressing the glial marker Repo in brat-RNAi brain. (I,J) Higher magnification image of brat-RNAi brain showing cells that do not express Tub-cherry, but that show Miranda expression. bratIR is brat-RNAi. Scale bar: 150 um for (C-F), 100 um for (G,H), 10um for (I,J).
Supplementary Figure Legends from The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis
Authors: Astudillo Luisana , Da Silva Thiago G. , Wang Zhiqiang , Han Xiaoqing , Jin Ke , VanWye Jeffrey , Zhu Xiaoxia , Weaver Kelly , Oashi Taiji , Lopes Pedro E.M. , Orton Darren , Neitzel Leif R. , Lee Ethan , Landgraf Ralf , Robbins David J. , MacKerell Alexander D. , Capobianco Anthony J.
Published: April 2023

Description of the contents of supplementary figures 1, 2 and 3.
Supplementary data from Nkx2.8 Inhibits Epithelial–Mesenchymal Transition in Bladder Urothelial Carcinoma via Transcriptional Repression of Twist1
Authors: Yu Chunping , Liu Zhuowei , Chen Qiuhong , Li Yonghong , Jiang Lijuan , Zhang Zhiling , Zhou Fangjian
Published: April 2023

Supplemental figure legends and tables for sequences of primers
Figure S7 from Nkx2.8 Inhibits Epithelial–Mesenchymal Transition in Bladder Urothelial Carcinoma via Transcriptional Repression of Twist1
Authors: Yu Chunping , Liu Zhuowei , Chen Qiuhong , Li Yonghong , Jiang Lijuan , Zhang Zhiling , Zhou Fangjian
Published: April 2023

Survival significance of Twist1 in human UC
Supplementary Tables from Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer
Authors: Hall Zoe , Ament Zsuzsanna , Wilson Catherine H. , Burkhart Deborah L. , Ashmore Tom , Koulman Albert , Littlewood Trevor , Evan Gerard I. , Griffin Julian L.
Published: April 2023

LC-MS/MS method details for eicosanoid analysis (Tables S1 and S2); Lipid ID by accurate mass and tandem MS (Tables S3 and S4); Fold change for eicosanoid-related species with MYC activated (Table S5).
Figure S2 from Nkx2.8 Inhibits Epithelial–Mesenchymal Transition in Bladder Urothelial Carcinoma via Transcriptional Repression of Twist1
Authors: Yu Chunping , Liu Zhuowei , Chen Qiuhong , Li Yonghong , Jiang Lijuan , Zhang Zhiling , Zhou Fangjian
Published: April 2023

Representative images of orthotopic xenograft bladder cancer model with T24/vector and T24/Nkx2.8 cells
Figure S5 from Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer
Authors: Hall Zoe , Ament Zsuzsanna , Wilson Catherine H. , Burkhart Deborah L. , Ashmore Tom , Koulman Albert , Littlewood Trevor , Evan Gerard I. , Griffin Julian L.
Published: April 2023

Example chromatograms for eicosanoid analysis by LC-MS/MS.
Figure S4 from Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer
Authors: Hall Zoe , Ament Zsuzsanna , Wilson Catherine H. , Burkhart Deborah L. , Ashmore Tom , Koulman Albert , Littlewood Trevor , Evan Gerard I. , Griffin Julian L.
Published: April 2023

Staining for proliferation and apoptosis before and after MYC deactivation.
Legends for supplementary Figures from RASSF1A Directly Antagonizes RhoA Activity through the Assembly of a Smurf1-Mediated Destruction Complex to Suppress Tumorigenesis
Authors: Lee Min-Goo , Jeong Seong-In , Ko Kyung-Phil , Park Soon-Ki , Ryu Byung-Kyu , Kim Ick-Young , Kim Jeong-Kook , Chi Sung-Gil
Published: April 2023

Experimental methods and materials and brief summary of the results for Supplementary data (Figures S1-S7)
Figure S3 from Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer
Authors: Hall Zoe , Ament Zsuzsanna , Wilson Catherine H. , Burkhart Deborah L. , Ashmore Tom , Koulman Albert , Littlewood Trevor , Evan Gerard I. , Griffin Julian L.
Published: April 2023

Liquid extraction surface analysis mass spectrometry differentiates normal from tumour tissue.
Figure S5 from RASSF1A Directly Antagonizes RhoA Activity through the Assembly of a Smurf1-Mediated Destruction Complex to Suppress Tumorigenesis
Authors: Lee Min-Goo , Jeong Seong-In , Ko Kyung-Phil , Park Soon-Ki , Ryu Byung-Kyu , Kim Ick-Young , Kim Jeong-Kook , Chi Sung-Gil
Published: April 2023

Figure S5. RASSF1A inhibits tumor-promoting activity of RhoA. A, RASSF1A regulation of cyclins and CDK inhibitors in a RhoA-dependent manner. B, Blockade of RhoA repression of p21WAF1 expression by WT-RASSF1A but not by RASSF1A-Î”256-277 and RASSF1A-Î”69-82. C, Inhibitory effect of WT-RASSF1A but not of RASSF1A-Î”256-277 and RASSF1A-Î”69-82 on EGF-induced DNA synthesis. DNA synthesis was measured by (3H)thymidine uptake assay after 24 h treatment. Data represent the mean {plus minus} SD (n = 3 experimental replicates; **, P < 0.01, Student t test). D, Flow cytometric assay of sub-G1 fraction showing no apoptotic activity of RASSF1A-R269F. E, RASSF1A inhibition of cell migration in a RhoA-dependent manner. Cell migration was compared at 18 h after artificial scratch. F, Matrigel assays showing blockade of EGF-induced tumor cell invasion by WT-RASSF1A but not by RhoA binding-deficient mutants (R269F and L266G). Data represent the mean {plus minus} SD (**, P < 0.01, Student t test). G, Time- and dose-dependent RhoA activation by TGF-Î²1 in DU145 cells. GTP-RhoA level was determined by GTPase pull-down assay using Rhotekin RBD-agarose. H, A crucial role for RhoA in TGF-Î²1-induced EMT in DU145 cells. The cells were transfected with siRhoA, siCdc42 or siRac1 and treated with TGF-Î²1(2 ng/ml, 48 h). I, Effect of RASSF1A or Smurf1 depletion on TGF-Î²1-induced EMT. HeLa and HaCaT cells transfected with siRASSF1A or siSmurf1 were treated with TGF-Î²1 (2 ng/ml, 48 h). TGF-Î²1-induced EMT was evaluated by microscopic analysis.
Figure S1 from RASSF1A Directly Antagonizes RhoA Activity through the Assembly of a Smurf1-Mediated Destruction Complex to Suppress Tumorigenesis
Authors: Lee Min-Goo , Jeong Seong-In , Ko Kyung-Phil , Park Soon-Ki , Ryu Byung-Kyu , Kim Ick-Young , Kim Jeong-Kook , Chi Sung-Gil
Published: April 2023

Figure S1. RASSF1A stimulates GTP-RhoA degradation. A, RASSF1A inhibition of RhoA-induced membrane ruffling and protrusion. GFP-expressing cells were transfected with RASSF1A and/or RhoA-G14V. B, RASSF1A suppression of RhoA-mediated FAK, MLC, and LIMK1/2 phosphorylation. C, No effect of RASSF1A on Ras activation of Raf-Mek-Erk signaling. A549 cells were co-transfected with RASSF1A-V5 and either HA-tagged H-Ras-G14V, K-Ras-G14V, or N-Ras-Q61R. Immunoblots were performed at 48 h after transfection. D. Effect of RASSF1A depletion on EGF (10 ng/ml) induction of GTP-RhoA. E. RASSF1A suppression of serum- or LPA-mediated GTP-RhoA induction. Cells transfected with either RASSF1A or RASSF1C were maintained in the absence of serum for 24 h and then exposed to serum or LPA. GTP-RhoA level was determined by GTPase pull-down assay. F, No effect of RASSF1A on Rho-GAP and Rho-GEF levels. G, A CHX assay showing reduction of the RhoA protein half-life by RASSF1A. RhoA intensities were measured by densitometric scanning of the immunoblot gels (Fig. 1H) and adjusted for Tubulin.
Figure S1-S12 from Brain-Mimetic 3D Culture Platforms Allow Investigation of Cooperative Effects of Extracellular Matrix Features on Therapeutic Resistance in Glioblastoma
Authors: Xiao Weikun , Zhang Rongyu , Sohrabi Alireza , Ehsanipour Arshia , Sun Songping , Liang Jesse , Walthers Christopher M. , Ta Lisa , Nathanson David A. , Seidlits Stephanie K.
Published: April 2023

Supplementary figures S1-S12 providing necessary data on additional animal xenograft experiments, essential information characterizing cell lines used in manuscript, and controls for immunostaining and western blots. This supplementary file also provides data for experiment on additional cell lines.
Supplemental Figure 1 from Cyclin A1 and P450 Aromatase Promote Metastatic Homing and Growth of Stem-like Prostate Cancer Cells in the Bone Marrow
Authors: Miftakhova Regina , Hedblom Andreas , Semenas Julius , Robinson Brian , Simoulis Athanasios , Malm Johan , Rizvanov Albert , Heery David M. , Mongan Nigel P. , Maitland Norman J. , Allegrucci Cinzia , Persson Jenny L.
Published: April 2023

PC3M cells overexpressing cyclin A1 initiated macro-metastases in distant organs in xenograft mice.
Supplemental Figure 3 from JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma
Authors: Chan Tiffany Sin Yu , Hawkins Cynthia , Krieger Jonathan R. , McGlade C. Jane , Huang Annie
Published: April 2023

LEDGF promotes MB cell survival
Supplemental Figure 2 from JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma
Authors: Chan Tiffany Sin Yu , Hawkins Cynthia , Krieger Jonathan R. , McGlade C. Jane , Huang Annie
Published: April 2023

Effect of JPO2 on cell death induced by serum starvation, chemotherapeutics and radiation
Supplemental Figure 8: Chao1 and Shannon richness estimates and indicator OTUs for AOM/DSS mice. from HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis
Authors: Lang Michaela , Berry David , Passecker Katharina , Mesteri Ildiko , Bhuju Sabin , Ebner Florian , Sedlyarov Vitaly , Evstatiev Rayko , Dammann Kyle , Loy Alexander , Kuzyk Orest , Kovarik Pavel , Khare Vineeta , Beibel Martin , Roma Guglielmo , Meisner-Kober Nicole , Gasche Christoph
Published: April 2023

Phylum and family levels of APCMin and AOM/DSS mouse feces upon MS-444 treatment.
Supplemental table 1 from An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell–like Behaviors Contributing to Disease Progression
Authors: Hayashi Hiromitsu , Higashi Takaaki , Yokoyama Naomi , Kaida Takayoshi , Sakamoto Keita , Fukushima Yukiko , Ishimoto Takatsugu , Kuroki Hideyuki , Nitta Hidetoshi , Hashimoto Daisuke , Chikamoto Akira , Oki Eiji , Beppu Toru , Baba Hideo
Published: April 2023

Characteristics of 110 patients with hepatocellular carcinoma
Supplemental Figure 4: CRISPR/Cas9 HuR ko in RAW 264.7 macrophage cells. from HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis
Authors: Lang Michaela , Berry David , Passecker Katharina , Mesteri Ildiko , Bhuju Sabin , Ebner Florian , Sedlyarov Vitaly , Evstatiev Rayko , Dammann Kyle , Loy Alexander , Kuzyk Orest , Kovarik Pavel , Khare Vineeta , Beibel Martin , Roma Guglielmo , Meisner-Kober Nicole , Gasche Christoph
Published: April 2023

CRISPR/Cas9 HuR ko in RAW 264.7 macrophage cells confirmed by Sanger sequencing and Western blot analysis.
Supplementary Figure 7. from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma
Authors: Cadamuro Massimiliano , Spagnuolo Gaia , Sambado Luisa , Indraccolo Stefano , Nardo Giorgia , Rosato Antonio , Brivio Simone , Caslini Chiara , Stecca Tommaso , Massani Marco , Bassi Nicolò , Novelli Eugenio , Spirli Carlo , Fabris Luca , Strazzabosco Mario
Published: April 2023

Supplementary Figure 7. LDM PTX did not affect the splenic tumor mass in SCID mice xenotransplanted with EGI-1 cells, in vivo.
Suppl. Figure 6 from HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors
Authors: Budina-Kolomets Anna , Webster Marie R. , Leu Julia I-Ju , Jennis Matthew , Krepler Clemens , Guerrini Anastasia , Kossenkov Andrew V. , Xu Wei , Karakousis Giorgos , Schuchter Lynn , Amaravadi Ravi K. , Wu Hong , Yin Xiangfan , Liu Qin , Lu Yiling , Mills Gordon B. , Xu Xiaowei , George Donna L. , Weeraratna Ashani T. , Murphy Maureen E.
Published: April 2023

Impact of PET-16 on ER stress Melanoma cell lines 1205Lu and WM852 were treated with DMSO or 1 μM PET-16 for 0, 8 and 24 hours.
Suppl. Figure 4 from HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors
Authors: Budina-Kolomets Anna , Webster Marie R. , Leu Julia I-Ju , Jennis Matthew , Krepler Clemens , Guerrini Anastasia , Kossenkov Andrew V. , Xu Wei , Karakousis Giorgos , Schuchter Lynn , Amaravadi Ravi K. , Wu Hong , Yin Xiangfan , Liu Qin , Lu Yiling , Mills Gordon B. , Xu Xiaowei , George Donna L. , Weeraratna Ashani T. , Murphy Maureen E.
Published: April 2023

Impact of PET-16 on melanoma in vitro A. Immunoprecipitation-western analysis in the H1299 cell line using antisera to HSP70 and IgG, followed by Western blot analysis for the associated total and phosphorylated FAK. B. 1205Lu and WM852 cells were treated with DMSO or 1 μM PET-16 for 24 hours.
Supplementary Figure 3 from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma
Authors: Cadamuro Massimiliano , Spagnuolo Gaia , Sambado Luisa , Indraccolo Stefano , Nardo Giorgia , Rosato Antonio , Brivio Simone , Caslini Chiara , Stecca Tommaso , Massani Marco , Bassi Nicolò , Novelli Eugenio , Spirli Carlo , Fabris Luca , Strazzabosco Mario
Published: April 2023

Supplementary Figure 3. In contrast with high doses, low dose PTX did not affect cell proliferation, viability, and apoptosis of CCA-TV3 cells.
Suppl. Figure 1 from HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors
Authors: Budina-Kolomets Anna , Webster Marie R. , Leu Julia I-Ju , Jennis Matthew , Krepler Clemens , Guerrini Anastasia , Kossenkov Andrew V. , Xu Wei , Karakousis Giorgos , Schuchter Lynn , Amaravadi Ravi K. , Wu Hong , Yin Xiangfan , Liu Qin , Lu Yiling , Mills Gordon B. , Xu Xiaowei , George Donna L. , Weeraratna Ashani T. , Murphy Maureen E.
Published: April 2023

Chemical structures of the HSP70 inhibitors used in this study
Supplemental Figures S1-S9 from Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α
Authors: Lim Sangbin , Liu Hao , da Silva Luciana Madeira , Arora Ritu , Liu Zixing , Phillips Joshua B. , Schmitt David C. , Vu Tung , McClellan Steven , Lin Yifeng , Lin Wensheng , Piazza Gary A. , Fodstad Oystein , Tan Ming
Published: April 2023

Fig. S1: Glucose uptake and lactate production in B7-H3 knockdown Fig. S2: Growth inhibition W/O B7-H3 Fig S3: Proliferation assay in glucose deprivation. Fig. S4: Expression in B7-H3 knockdown w/o CoCl2. Fig. S5: mRNA levels. Fig. S6: Reduction of ROS by ROS scavenger in B7-H3 overexpression. Fig. S7: G6PD and SOD activity. Fig. S8: Growth Inhibition by ROS scavenger. Fig. S9: Immunohistochemistry analysis of xenograft tumors.
Supplemental Figure Legends from Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α
Authors: Lim Sangbin , Liu Hao , da Silva Luciana Madeira , Arora Ritu , Liu Zixing , Phillips Joshua B. , Schmitt David C. , Vu Tung , McClellan Steven , Lin Yifeng , Lin Wensheng , Piazza Gary A. , Fodstad Oystein , Tan Ming
Published: April 2023

Legends for Supplementary Figures
Supplementary Movie S1 from Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade
Authors: Chen Michelle B. , Lamar John M. , Li Ran , Hynes Richard O. , Kamm Roger D.
Published: April 2023

Time-lapse confocal microscopy (20X) of one representative region of interest with control MDA-MB 231 extravasating (green) from in vitro microvascular networks (HUVEC; red).
Supplementary Legends from Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade
Authors: Chen Michelle B. , Lamar John M. , Li Ran , Hynes Richard O. , Kamm Roger D.
Published: April 2023

Legend for Supplementary Figures S1-S8, Supplementary Tables S1-S2, and Supplementary Movie S1.
Supplementary Tables from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-Deoxycytidine
Authors: Leadem Benjamin R. , Kagiampakis Ioannis , Wilson Catherine , Cheung Tommy K. , Arnott David , Trojer Patrick , Classon Marie , Easwaran Hariharan , Baylin Stephen B.
Published: April 2023

Contains Tables S1 and S2. Supplementary Table 1: List of PCR primers. Supplementary Table 2: Sensitivity of Breast Cancer Cell Lines to CPI-455 Cell Viability was measured following exposure to CPI-455 for 8 days.
Supplemental Figure 1 from Amphiregulin Is a Critical Downstream Effector of Estrogen Signaling in ERα-Positive Breast Cancer
Authors: Peterson Esther A. , Jenkins Edmund C. , Lofgren Kristopher A. , Chandiramani Natasha , Liu Hui , Aranda Evelyn , Barnett Maryia , Kenny Paraic A.
Published: April 2023

Additional representative examples of Amphiregulin immunostaining in breast cancer specimens
Supplementary Table 9 from MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome
Authors: Wragg Joseph W. , Finnity Jonathan P. , Anderson Jane A. , Ferguson Henry J.M. , Porfiri Emilio , Bhatt Rupesh I. , Murray Paul G. , Heath Victoria L. , Bicknell Roy
Published: April 2023

Supplementary Table 9: Key clinical data for clear cell RCC cohort 2 showing overall survival (OS)
Supplementary Table 7 from MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome
Authors: Wragg Joseph W. , Finnity Jonathan P. , Anderson Jane A. , Ferguson Henry J.M. , Porfiri Emilio , Bhatt Rupesh I. , Murray Paul G. , Heath Victoria L. , Bicknell Roy
Published: April 2023

Supplementary Table 7: Key clinical data for different types of kidney cancer and metastasis
Supplementary Table 9 from An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers
Authors: Prueitt Robyn L. , Wallace Tiffany A. , Glynn Sharon A. , Yi Ming , Tang Wei , Luo Jun , Dorsey Tiffany H. , Stagliano Katherine E. , Gillespie John W. , Hudson Robert S. , Terunuma Atsushi , Shoe Jennifer L. , Haines Diana C. , Yfantis Harris G. , Han Misop , Martin Damali N. , Jordan Symone V. , Borin James F. , Naslund Michael J. , Alexander Richard B. , Stephens Robert M. , Loffredo Christopher A. , Lee Dong H. , Putluri Nagireddy , Sreekumar Arun , Hurwitz Arthur A. , Ambs Stefan
Published: April 2023

Supplementary Table 9: Genes differently expressed between nicotine-treated and untreated 22Rv1 cells.
Supplementary Table S2 from Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Authors: Kress Theresia R. , Pellanda Paola , Pellegrinet Luca , Bianchi Valerio , Nicoli Paola , Doni Mirko , Recordati Camilla , Bianchi Salvatore , Rotta Luca , Capra Thelma , Ravà Micol , Verrecchia Alessandro , Radaelli Enrico , Littlewood Trevor D. , Evan Gerard I. , Amati Bruno
Published: April 2023

Gene ontology analyses of Myc-dependent and -independent DEG categories.
Supplementary Table S4 from Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome
Authors: You Sungyong , Knudsen Beatrice S. , Erho Nicholas , Alshalalfa Mohammed , Takhar Mandeep , Al-deen Ashab Hussam , Davicioni Elai , Karnes R. Jeffrey , Klein Eric A. , Den Robert B. , Ross Ashley E. , Schaeffer Edward M. , Garraway Isla P. , Kim Jayoung , Freeman Michael R.
Published: April 2023

List of 428 SEGs.
Supplementary Figure and Table Legends from Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Authors: Kress Theresia R. , Pellanda Paola , Pellegrinet Luca , Bianchi Valerio , Nicoli Paola , Doni Mirko , Recordati Camilla , Bianchi Salvatore , Rotta Luca , Capra Thelma , Ravà Micol , Verrecchia Alessandro , Radaelli Enrico , Littlewood Trevor D. , Evan Gerard I. , Amati Bruno
Published: April 2023

Legend for Supplementary Figures S1-S6 and Supplementary Table S1-S3.
Supplementary Table S2 from Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome
Authors: You Sungyong , Knudsen Beatrice S. , Erho Nicholas , Alshalalfa Mohammed , Takhar Mandeep , Al-deen Ashab Hussam , Davicioni Elai , Karnes R. Jeffrey , Klein Eric A. , Den Robert B. , Ross Ashley E. , Schaeffer Edward M. , Garraway Isla P. , Kim Jayoung , Freeman Michael R.
Published: April 2023

Publications from which the pathway activation gene sets were obtained.
Supplementary Table S1 from Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome
Authors: You Sungyong , Knudsen Beatrice S. , Erho Nicholas , Alshalalfa Mohammed , Takhar Mandeep , Al-deen Ashab Hussam , Davicioni Elai , Karnes R. Jeffrey , Klein Eric A. , Den Robert B. , Ross Ashley E. , Schaeffer Edward M. , Garraway Isla P. , Kim Jayoung , Freeman Michael R.
Published: April 2023

List of gene expression datasets included in the analysis of the DISC cohort.
Supplementary Figure S4 from Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Authors: Kress Theresia R. , Pellanda Paola , Pellegrinet Luca , Bianchi Valerio , Nicoli Paola , Doni Mirko , Recordati Camilla , Bianchi Salvatore , Rotta Luca , Capra Thelma , Ravà Micol , Verrecchia Alessandro , Radaelli Enrico , Littlewood Trevor D. , Evan Gerard I. , Amati Bruno
Published: April 2023

Analyses and characterization of Myc-dependent and Myc-independent differentially expressed genes.
Supplementary Figure S2 from Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Authors: Kress Theresia R. , Pellanda Paola , Pellegrinet Luca , Bianchi Valerio , Nicoli Paola , Doni Mirko , Recordati Camilla , Bianchi Salvatore , Rotta Luca , Capra Thelma , Ravà Micol , Verrecchia Alessandro , Radaelli Enrico , Littlewood Trevor D. , Evan Gerard I. , Amati Bruno
Published: April 2023

tet-MycWT and tet-MycVD overexpression induces liver tumorigenesis.
Supplement method and figures from A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma
Authors: Wallace Eli M. , Rizzi James P. , Han Guangzhou , Wehn Paul M. , Cao Zhaodan , Du Xinlin , Cheng Tzuling , Czerwinski Robert M. , Dixon Darryl D. , Goggin Barry S. , Grina Jonas A. , Halfmann Megan M. , Maddie Melissa A. , Olive Sarah R. , Schlachter Stephen T. , Tan Huiling , Wang Bin , Wang Keshi , Xie Shanhai , Xu Rui , Yang Hanbiao , Josey John A.
Published: April 2023

Supplementary method includes detailed experimental procedure for the synthesis of PT2385. Supplementary Figures 1-7 - Lack of cytotoxicity of PT2385 in cultured 786-O and A498 cells (1); PT2385 pharmacokinetics in CD-1 mice (2); Inhibition of HIF-2ï�¡ gene expression and circulating hVEGFa in A498 mouse xenograft model after treatment with PT2385 (3); HIF-2ï�¡ mRNA and protein levels in 786-O cells in vitro after treatment with PT2385 (4); Levels of HIF-1ï�¡ and HIF-2ï�¡ in patient-derived xenograft tumors (5); Body weight of mice in efficacy studies treated with either vehicle, PT2385 or sunitinib (6); Binding of PT2385 to rat HIF-2ï�¡ as determined by ITC and inhibition of mouse kidney EPO gene expression with PT2385 treatment (7).
Supplementary figure legend from Nestin Mediates Hedgehog Pathway Tumorigenesis
Authors: Li Peng , Lee Eric H. , Du Fang , Gordon Renata E. , Yuelling Larra W. , Liu Yongqiang , Ng Jessica M.Y. , Zhang Hao , Wu Jinhua , Korshunov Andrey , Pfister Stefan M. , Curran Tom , Yang Zeng-jie
Published: April 2023

Supplementary figure legend
Supplementary Figure S4 from Nestin Mediates Hedgehog Pathway Tumorigenesis
Authors: Li Peng , Lee Eric H. , Du Fang , Gordon Renata E. , Yuelling Larra W. , Liu Yongqiang , Ng Jessica M.Y. , Zhang Hao , Wu Jinhua , Korshunov Andrey , Pfister Stefan M. , Curran Tom , Yang Zeng-jie
Published: April 2023

Nestin knockdown in MB cells by Nestin shRNA
159930_1_supp_0_t72r9t.jpg from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma
Authors: Harbst Katja , Lauss Martin , Cirenajwis Helena , Isaksson Karolin , Rosengren Frida , Törngren Therese , Kvist Anders , Johansson Maria C. , Vallon-Christersson Johan , Baldetorp Bo , Borg Åke , Olsson Håkan , Ingvar Christian , Carneiro Ana , Jönsson Göran
Published: April 2023

159930_1_supp_0_t72r9t.jpg from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma
Fig S5 from Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth
Authors: Cormerais Yann , Giuliano Sandy , LeFloch Renaud , Front Benoît , Durivault Jerome , Tambutté Eric , Massard Pierre-André , de la Ballina Laura Rodriguez , Endou Hitoshi , Wempe Michael F. , Palacin Manuel , Parks Scott K. , Pouyssegur Jacques
Published: April 2023

Figure S5: Rescue of CD98 expression in A549 LAT1KO cells
159930_1_supp_0_n72rg6.xls from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma
Authors: Harbst Katja , Lauss Martin , Cirenajwis Helena , Isaksson Karolin , Rosengren Frida , Törngren Therese , Kvist Anders , Johansson Maria C. , Vallon-Christersson Johan , Baldetorp Bo , Borg Åke , Olsson Håkan , Ingvar Christian , Carneiro Ana , Jönsson Göran
Published: April 2023

159930_1_supp_0_n72rg6.xls from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma
Fig S1 from Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth
Authors: Cormerais Yann , Giuliano Sandy , LeFloch Renaud , Front Benoît , Durivault Jerome , Tambutté Eric , Massard Pierre-André , de la Ballina Laura Rodriguez , Endou Hitoshi , Wempe Michael F. , Palacin Manuel , Parks Scott K. , Pouyssegur Jacques
Published: April 2023

Figure S1: Quantification of respective mRNA and protein expression of each member of the CD98/LAT1 complex and β1 integrin in the various cell lines and knockout derivatives.
Supplementary Materials and Methods from Genomic Loss of DUSP4 Contributes to the Progression of Intraepithelial Neoplasm of Pancreas to Invasive Carcinoma
Authors: Hijiya Naoki , Tsukamoto Yoshiyuki , Nakada Chisato , Tung Nguyen Lam , Kai Tomoki , Matsuura Keiko , Shibata Kohei , Inomata Masafumi , Uchida Tomohisa , Tokunaga Akinori , Amada Kohei , Shirao Kuniaki , Yamada Yasunari , Mori Hiromu , Takeuchi Ichiro , Seto Masao , Aoki Masahiro , Takekawa Mutsuhiro , Moriyama Masatsugu
Published: April 2023

Description of additional methods and procedures used in the study.
Supplementary Table S3 from Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus
Authors: Harlow Matt L. , Maloney Nichole , Roland Joseph , Guillen Navarro Maria Jose , Easton Matthew K. , Kitchen-Goosen Susan M. , Boguslawski Elissa A. , Madaj Zachary B. , Johnson Ben K. , Bowman Megan J. , D'Incalci Maurizio , Winn Mary E. , Turner Lisa , Hostetter Galen , Galmarini Carlos María , Aviles Pablo M. , Grohar Patrick J.
Published: April 2023

Supplementary Table S3 Table showing list of EWS-FLI1 targets with corresponding references.
Supplementary Figure S5 from Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus
Authors: Harlow Matt L. , Maloney Nichole , Roland Joseph , Guillen Navarro Maria Jose , Easton Matthew K. , Kitchen-Goosen Susan M. , Boguslawski Elissa A. , Madaj Zachary B. , Johnson Ben K. , Bowman Megan J. , D'Incalci Maurizio , Winn Mary E. , Turner Lisa , Hostetter Galen , Galmarini Carlos María , Aviles Pablo M. , Grohar Patrick J.
Published: April 2023

Supplementary Figure S5 Mean tumor volume and corresponding mouse weights for cohorts of mice bearing the Ewing sarcoma xenografts TC32 or TC71 as a function of days of treatment with vehicle control (black), lurbinectedin (red), irinotecan (blue) or the combination of lurbinectedin and irinotecan (green).
Suppl Table S2 from Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma
Authors: Koso Hideto , Yi Hungtsung , Sheridan Paul , Miyano Satoru , Ino Yasushi , Todo Tomoki , Watanabe Sumiko
Published: April 2023

Assays used for TaqMan array
Supplemental Figure S1 from STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation
Authors: Lemos Henrique , Mohamed Eslam , Huang Lei , Ou Rong , Pacholczyk Gabriela , Arbab Ali S. , Munn David , Mellor Andrew L.
Published: April 2023

Signaling requirements for optimal LLC or EL4 tumor growth.
Suppl Figure S2 from Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma
Authors: Koso Hideto , Yi Hungtsung , Sheridan Paul , Miyano Satoru , Ino Yasushi , Todo Tomoki , Watanabe Sumiko
Published: April 2023

LARP4B overexpression suppresses glioma cell growth
Supplementary Table 2 from Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses
Authors: Colli Leandro M. , Machiela Mitchell J. , Myers Timothy A. , Jessop Lea , Yu Kai , Chanock Stephen J.
Published: April 2023

Comparison between TCGA and TumorPortal (replication) set
Supplementary Figure Legends from Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses
Authors: Colli Leandro M. , Machiela Mitchell J. , Myers Timothy A. , Jessop Lea , Yu Kai , Chanock Stephen J.
Published: April 2023

Supplementary Figure Legends
Table S1 from Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Authors: Cao Ji , Wang Yijie , Dong Rong , Lin Guanyu , Zhang Ning , Wang Jing , Lin Nengming , Gu Yongchuan , Ding Ling , Ying Meidan , He Qiaojun , Yang Bo
Published: April 2023

Table S1.The list of proteins with 3-fold change in WSB1 overexpression KHOS/NP cells using SILAC assay.
Supplementary Figure 2 from Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses
Authors: Colli Leandro M. , Machiela Mitchell J. , Myers Timothy A. , Jessop Lea , Yu Kai , Chanock Stephen J.
Published: April 2023

Violin plot for the number of non-synonymous mutations for smoking (dark gray) and (light gray) non-smoking patients for bladder urothelial carcinoma (BLCA), head and neck squamous cell carcinoma (HNSC), kidney chromophobe (KICH), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), and pancreatic adenocarcinoma (PAAD).
Figure S6 from Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Authors: Cao Ji , Wang Yijie , Dong Rong , Lin Guanyu , Zhang Ning , Wang Jing , Lin Nengming , Gu Yongchuan , Ding Ling , Ying Meidan , He Qiaojun , Yang Bo
Published: April 2023

Time-lapse movie of representative KHOS/NP cells infected with control lentivirus (pCCL) on gelatin-coated surfaces.
Supplementary Figure Legend from IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis
Authors: Rajurkar Mihir , Dang Kyvan , Fernandez-Barrena Maite G. , Liu Xiangfan , Fernandez-Zapico Martin E. , Lewis Brian C. , Mao Junhao
Published: April 2023

Supplemental figure legends
Supplementary Figure 5 from The Error-Prone DNA Polymerase κ Promotes Temozolomide Resistance in Glioblastoma through Rad17-Dependent Activation of ATR-Chk1 Signaling
Authors: Peng Chenghao , Chen Zhengxin , Wang Shuai , Wang Hong-Wei , Qiu Wenjin , Zhao Lin , Xu Ran , Luo Hui , Chen Yuanyuan , Chen Dan , You Yongping , Liu Ning , Wang Huibo
Published: April 2023

qPCR analysis of Rad17 mRNA expression in Pol κ-depleted recurrent GBM1, GBM2 and U87 cells or control cells.
Figure S2 from Clonotypic Diversification of Intratumoral T Cells Following Sipuleucel-T Treatment in Prostate Cancer Subjects
Authors: Sheikh Nadeem , Cham Jason , Zhang Li , DeVries Todd , Letarte Simon , Pufnock Jeff , Hamm David , Trager James , Fong Lawrence
Published: April 2023

Supplementary Figure S2 - Assessments of unique TCR sequences in the blood for healthy donors and for sipuleucel-T-treated subjects were performed on PBMCs taken before the preparation of each sipuleucel-T-treatment. A, TCR sequence profiles in healthy donors and sipuleucel-T-treated subjects with prostate cancer over time. Sipuleucel-T-treated subjects had a significantly higher mean number of productive TCR sequences at baseline (Week 0) compared with Week 2 and Week 4 (P < 0.01, paired t-test on the log scale). No differences in mean productive sequences in healthy donors over time were detected (NS (not significant), paired t-test on the log scale). The number of unique sequences was higher in sipuleucel-T-treated subjects at Week 0 and Week 2 compared with healthy donors (Wilcoxon one-sided test, P = 0.025 and 0.053, respectively). B, Shannon diversity index for TCR repertoire in blood from healthy donors and sipuleucel-T-treated subjects with prostate cancer. The median Shannon diversity index of healthy donors and a sipuleucel-T-treated subject at baseline (Week 0) and Weeks 2 and 4 is shown. TCR sequence diversity was higher in sipuleucel-T-treated subjects compared with healthy donors. Shannon diversity index decreased at Weeks 2 and 4 compared with baseline in sipuleucel-T-treated subjects (P < 0.001), whereas Shannon diversity index remained stable over time in healthy donors.
Supplemental Figure S1 from Polysome Profiling Links Translational Control to the Radioresponse of Glioblastoma Stem-like Cells
Authors: Wahba Amy , Rath Barbara H. , Bisht Kheem , Camphausen Kevin , Tofilon Philip J.
Published: April 2023

IR-induced changes in the transcriptome
Supplementary Materials and Methods from Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes
Authors: Markowitz Geoffrey J. , Yang Pengyuan , Fu Jing , Michelotti Gregory A. , Chen Rui , Sui Jianhua , Yang Bin , Qin Wen-Hao , Zhang Zheng , Wang Fu-Sheng , Diehl Anna Mae , Li Qi-Jing , Wang Hongyang , Wang Xiao-Fan
Published: April 2023

More detailed descriptions of patients and experimental protocols.
Supplementary Figure S5 from Multiple Myeloma Impairs Bone Marrow Localization of Effector Natural Killer Cells by Altering the Chemokine Microenvironment
Authors: Ponzetta Andrea , Benigni Giorgia , Antonangeli Fabrizio , Sciumè Giuseppe , Sanseviero Emilio , Zingoni Alessandra , Ricciardi Maria Rosaria , Petrucci Maria Teresa , Santoni Angela , Bernardini Giovanni
Published: April 2023

Supplementary Figure S5. Proposed model: MM alteration of chemokine/chemokine receptor axes in BM shapes NK cell effector function by reducing the number of functional KLRG1- subset
Supplementary Figure Legends from Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes
Authors: Markowitz Geoffrey J. , Yang Pengyuan , Fu Jing , Michelotti Gregory A. , Chen Rui , Sui Jianhua , Yang Bin , Qin Wen-Hao , Zhang Zheng , Wang Fu-Sheng , Diehl Anna Mae , Li Qi-Jing , Wang Hongyang , Wang Xiao-Fan
Published: April 2023

Legends for Supplementary Figures S1-S19.
Supplementary Figure S2 from Multiple Myeloma Impairs Bone Marrow Localization of Effector Natural Killer Cells by Altering the Chemokine Microenvironment
Authors: Ponzetta Andrea , Benigni Giorgia , Antonangeli Fabrizio , Sciumè Giuseppe , Sanseviero Emilio , Zingoni Alessandra , Ricciardi Maria Rosaria , Petrucci Maria Teresa , Santoni Angela , Bernardini Giovanni
Published: April 2023

Supplementary Figure S2. Reduced KLRG1- NK cell numbers in the BM of MM-bearing mice are not attributable to changes of cell survival or maturation
Supplemental Figure legends from Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone
Authors: Reynaud Caroline , Ferreras Laura , Di Mauro Paola , Kan Casina , Croset Martine , Bonnelye Edith , Pez Floriane , Thomas Clémence , Aimond Géraldine , Karnoub Antoine E. , Brevet Marie , Clézardin Philippe
Published: April 2023

Supplementary figure legends from S1 to S7
Supplementary Figures from Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer
Authors: Meder Lydia , Schuldt Philipp , Thelen Martin , Schmitt Anna , Dietlein Felix , Klein Sebastian , Borchmann Sven , Wennhold Kerstin , Vlasic Ignacija , Oberbeck Sebastian , Riedel Richard , Florin Alexandra , Golfmann Kristina , Schlößer Hans A. , Odenthal Margarete , Buettner Reinhard , Wolf Juergen , Hallek Michael , Herling Marco , von Bergwelt-Baildon Michael , Reinhardt H. Christian , Ullrich Roland T.
Published: April 2023

Supplementary data supporting an exhausted T cell phenotype in SCLC upon acquired resistance to PD1/PD-L1 blockade which is regulated by VEGF/VEGFR signaling and in addition, an immunosuppressive role of tumor-associated macrophages in the tumor microenvironment