bluuebunny/crossref_metadata_2025 huggingface dataset:
Treatment principles of children with pharyngeal tonsil pathology in the background of allergic rhinitis (literature review): A review
Authors: Orlova Yulya E. , Svistushkin Valery M. , Nikiforova Galina N. , Shevchik Elena A.
Published: May 2022

This article provides a review of different treatment for children with adenoids against a background of allergic rhinitis. An analysis of 35 papers published in Scopus and PubMed was carried out. Evaluation of the research results has shown that treatment of patients with pathology of lymphoid structures of the pharynx on the background of allergic rhinitis should be complex and individual in each clinical case.
Functional disorders of the respiratory system in patients with penetrating lung wounds: study prospective design
Authors: Savushkina Olga I. , Zaytsev Andrey A. , Malashenko Maria M. , Aseeva Nataliya A. , Astanin Pavel A. , Davydov Denis V. , Kryukov Evgeniy V.
Published: May 2022

Background. Lung function tests should be performed to patients with penetrating wounds of the lungs to identify lung function disorders, and the data obtained should be taken into account when correcting medical treatment and prescribing individual medical rehabilitation programs.
The aim was to study the impact of penetrating lung wounds on the lung function in the early recovery period.
Materials and methods. 13 patients were enrolled in the study, 100% male, median age 26 [21; 31] years. Spirometry, body plethysmography, and a diffusion test were performed on an average of 14 days from the injury.
Results. A prospective cross-sectional study was performed. A moderate decrease in the vital capacity (VC), the forced vital capacity (FVC), the volume of forced exhalation in the first second (FEV1) was revealed while the total lung capacity (TLCpl) and the FEV1/FVC ratio were within normal values. However, in 2 (15.4%) and 3 (23%) patients, a restrictive ventilation disorders (TLC lower limit of normal) was detected when using Global Lung Function Initiative (GLI) and European Community for Steel and Coal (ECSC) 1993 predicted value system, respectively. The residual lung (RV) and RV/TLCpl were increased. Functional residual capacity (FRC), FRCpl/TLCpl, airway resistance remained within normal values. The diffusion lung capacity impairment was detected in 92.3% and 61.5% cases according to the ECSC 1993 and the GLI system, respectively.
Conclusion. In the early period of recovery after penetrating lung wounds, a nonspecific pattern of ventilation disorders was the most often abnormality namely a decrease in VC while TLC and FEV1/FVC were within normal values. Less frequently, the classic restrictive pattern of ventilation disorders was diagnosed. Besides, the diffusion lung capacity impairment was detected. The system of predicted values has a significant impact on the frequency of detection of the lung function disorders. The revealed functional disorders should be taken into account for adjusting medical and rehabilitation interventions.
Ongoing symptomatic COVID-19 – practical advice: A review
Authors: Zaitsev Andrei A. , Leshchenko Igor' V.
Published: May 2022

Studying the consequences of COVID-19 is a global priority in various countries around the world. The term long-covid or ongoing symptomatic COVID-19 should include situations with clinical manifestations of the disease lasting more than 4 but less than 12 weeks from the onset of the disease. The most urgent problem today remains the management of patients with persistent symptoms of past COVID-19.
Permanent establishment in digital business
Authors: Jamroży Marcin , Majdowski Filip
Published: May 2022

Background: As to the taxation of a permanent establishment (PE), current tax solutions based on the physical presence of an enterprise in the territory of another country have been developed for traditional enterprises that do not pursue their business digitally, especially on the Internet. However, electronic business is largely based on intangible property, such as algorithms and user data. The taxation of digital business is a global problem that is dealt with by the EU and the OECD, among others.

Research purpose: The paper is designed to introduce the relevance and the consequences of the new EU and the OECD proposals for taxation of income resulting from digitalising economy in light of the permanent establishment standards.

Methods: The paper analyses legal sources and working materials, in particular of EU Directives and OECD Reports or Statements before and after the BEPS Project. A comparative analysis of tax implications under the current and planned regulations regarding the permanent establishment in digital business has been performed.

Conclusions: The OECD Inclusive Framework decided to move away from the problem of digitization in favor of globalization, and away from taxation of the largest technology giants in favor of taxing the biggest and most profitable companies. The PE concept under the 2021 Compromise has taken a significantly simplified form compared to the traditional notion of PE requiring analysis of the physical presence
Publikowanie informacji o realizowanej strategii podatkowej, czyli stawianie współczesnego pręgierza – wybrane problemy
Authors: Szymacha Adam
Published: May 2022

Przedmiot badań: Przedmiotem analizy będą przepisy o obowiązkowym ujawnianiu informacji o stosowanej strategii podatkowej, zawarte w art. 27C ustawy o podatku dochodowym od osób prawnych. Regulacja ta jest o tyle ciekawa, że teoretycznie przedstawia zmianę sposobu myślenia ustawodawcy o uszczelnianiu systemu podatkowego. Adresatem publikowanych informacji ma być zatem ogół społeczeństwa, nie zaś sama administracja skarbowa. W artykule tym podjęta zostanie próba sygnalizacji kilku niebezpiecznych tendencji ustawodawcy w formułowaniu nowych obowiązków sprawozdawczych.

Cel badawczy: Celem niniejszego artykułu jest dokonanie analizy przepisów o obowiązkowym publikowaniu informacji o realizowanej strategii podatkowej pod kątem konstytucyjnych zasad obowiązujących przy tworzeniu prawa podatkowego. Uzyskana w ten sposób ocena obowiązkowego publikowania strategii podatkowych posłuży także do wyciągnięcia wstępnych wniosków, dotyczących ewentualnych korekt albo dróg rozwoju polskiej instytucji informowania o strategiach podatkowych. Proponowane zmiany mogą przybliżyć polską regulację do realizacji celów społecznej kontroli, akcentowanej w uzasadnieniu do ustawy wprowadzającej. Całość zostanie uzupełniona analizą polskich regulacji, dotyczących obowiązkowego ujawniania informacji o realizowanej strategii podatkowej, w kontekście regulacji funkcjonujących w innych państwach.

Metoda badawcza: W artykule zastosowano analizę dogmatyczno-prawną oraz komparatystyczną analizę polskiej regulacji z regulacjami australijskimi i brytyjskimi. Dokonano też komparatystycznej analizy orzecznictwa Trybunału Konstytucyjnego. Analiza zawierać będzie także weryfikację motywów, jakie ustawodawca zawarł w uzasadnieniu do ustawy wprowadzającej nowy obowiązek.1

Wyniki: Wydaje się, że choć ustawodawca założył ambitne cele przyświecające nowej regulacji, to narusza on szereg zasad konstytucyjnych, w tym zasadę proporcjonalności, zakaz retroaktywności prawa i zasadę poprawnej legislacji. Jest to tym bardziej niepokojące, że ustawodawca znał regulacje wprowadzone w innych państwach, które lepiej realizują zakładane cele.
A decrease in municipal income from property tax as an externality of the zombie phenomenon in the real estate market in Poland
Authors: Antczak-Stępniak Agata
Published: May 2022

Background: Abandoned properties, including “zombie” objects, are common worldwide. Abandoned and decaying for years, they cause negative externalities for municipalities in the form of reduced income from property tax. There is some foreign literature on the subject; however, in Poland, the phenomenon of zombies in the real estate market remains generally unrecognized.

Research purpose: The article examines the problem of the external effect of zombie properties in the form of reduced municipal income from property tax in Poland.

Methods: Analysis of existing data and the case study method were applied in this article.

Conclusions: The possibilities of estimating the scale of the external effect in the form of reduced municipal income from property tax in Poland are limited due to the lack of relevant statistical data. However, the case studies show that although such a decrease in municipality income from property tax was not observed in the examples discussed, tax arrears of zombie objects are an external effect for these municipalities, especially smaller ones
Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response
Authors: Kose Shingo , Imai Kenichiro , Watanabe Ai , Nakai Akira , Suzuki Yutaka , Imamoto Naoko
Published: May 2022

Hikeshi mediates the nuclear import of the molecular chaperone HSP70 under heat-shock (acute heat stress) conditions, which is crucial for recovery from cellular damage. The cytoplasmic function of HSP70 is well studied, but its nuclear roles, particularly under nonstressed conditions, remain obscure. Here, we show that Hikeshi regulates the nucleocytoplasmic distribution of HSP70 not only under heat-shock conditions but also under nonstressed conditions. Nuclear HSP70 affects the transcriptional activity of HSF1 and nuclear proteostasis under nonstressed conditions. Depletion of Hikeshi induces a reduction in nuclear HSP70 and up-regulation of the mRNA expression of genes regulated by HSF1 under nonstressed conditions. In addition, the heat-shock response is impaired in Hikeshi-knockout cells. Our results suggest that HSF1 transcriptional activity is tightly regulated by nuclear HSP70 because nuclear-localized Hsp70 effectively suppresses transcriptional activity in a dose-dependent manner. Furthermore, the cytotoxicity of nuclear pathologic polyglutamine proteins was increased by Hikeshi depletion. Thus, proper nucleocytoplasmic distribution of HSP70, mediated by Hikeshi, is required for nuclear proteostasis and adaptive response to heat shock.
Expression regulation of genes is linked to their CpG density distributions around transcription start sites
Authors: Tian Hao , He Yueying , Xue Yue , Gao Yi Qin
Published: May 2022

The CpG dinucleotide and its methylation behaviors play vital roles in gene regulation. Previous studies have divided genes into several categories based on the CpG intensity around transcription starting sites and found that housekeeping genes tend to possess high CpG density, whereas tissue-specific genes are generally characterized by low CpG density. In this study, we investigated how the CpG density distribution of a gene affects its transcription and regulation pattern. Based on the CpG density distribution around transcription starting site, by means of a semi-supervised neural network we designed, which took data augmentation into account, we divided the human genes into three categories, and genes within each cluster shared similar CpG density distribution. Not only sequence properties, these different clusters exhibited distinctly different structural features, regulatory mechanisms, correlation patterns between the expression level and CpG/TpG density, and expression and epigenetic mark variations during tumorigenesis. For instance, the activation of cluster 3 genes relies more on 3D genome reorganization, compared with cluster 1 and 2 genes, whereas cluster 2 genes showed the strongest correlation between gene expression and H3K27me3. Genes exhibiting uncoupled correlation between gene regulation and histone modifications are mainly in cluster 3. These results emphasized that the usage of epigenetic marks in gene regulation is partially rooted in the sequence property of genes such as their CpG density distribution and explained to some extent why the relation between epigenetic marks and gene expression is controversial.
Meatball model of porcine DNA detection by TaqMan probe real-time PCR
Authors: Sajali N. , Ting S.M.L. , Koh C.C. , Desa M.N.M. , Wong S.C. , Abu Bakar S.
Published: May 2022

Food adulteration has attracted a great deal of public concern as it affects consumers of
different religious beliefs, social backgrounds and economic perspectives. Meat
adulteration usually occurs through the substitution of beef with pork due to its lower
price and manufacturer’s profit motivation. This study was conducted to detect porcine
DNA in a spiked meatball model using real-time quantitative polymerase chain reaction
(qPCR) targeting the cytochrome B gene through the designing of specific primers and
probe sequences. In this study, the amplification efficiency of the designed primers and
probe was 95%, with a correlation coefficient (R2
) of 0.997, following amplification with
a series of 10-fold serial dilutions of porcine DNA. The specificity of the probe was
evidenced by the absence of amplification from DNA of eight different meat species,
including chicken, cow, duck, quail, buffalo, rabbit, deer and mutton. Conversely, pork
DNA was detected at a threshold cycle of 13.47±0.31, following amplification of 10 ng/
µL DNA. In addition, the assay detected a level of pork DNA as low as 0.01 ng/µL in raw
spiked beef meatball models and 0.1 ng/µL in heat-treated spiked chicken and beef
meatball models. This study is critical, mainly for the Muslim and Jewish communities
and individuals who are allergic to pork.
Газофазный синтез легированного азотом алмазного покрытия из высокоскоростного потока микроволновой плазмы
Authors: Федосеева Ю.В. , Городецкий Д.В. , Баскакова К.И. , Шляхова Е.В. , Макарова А.А. , Юдин И.Б. , Тимошенко Н.И. , Плотников М.Ю. , Емельянов А.А. , Ребров А.К. , Окотруб А.В.
Published: May 2022

Легированное азотом поликристаллическое алмазное покрытие было получено методом высокоскоростного газоструйного химического осаждения из смеси метана и водорода с добавлением молекулярного азота. Активация реакционной смеси осуществлялась плазмой микроволнового разряда. В настоящей работе проведено сравнительное исследование морфологии, состава и строения легированных азотом и нелегированных алмазных покрытий с применением методов растровой электронной микроскопии, спектроскопии комбинационного рассеяния света, рентгеновской фотоэлектронной спектроскопии и спектроскопии ближней тонкой структуры рентгеновского поглощения. Показано, что легирование азотом приводит к уменьшению среднего размера микрокристаллов алмаза и их количества на подложке. Кроме этого, добавка молекулярного азота в реакционную смесь привела к формированию кристаллов алмаза более высокого качества, включающих меньшее количество кислород- и водородсодержащих функциональных групп и графитоподобного углерода. На поверхности легированного азотом алмазного покрытия выявлено около 0.6 ат.% азота, который находится в трех химических состояниях и влияет на ее гидрофильные свойства.
Neutrophil-to-Lymphocyte Ratio Changes in Rheumatoid Arthritis Patients with Oral Focus Infection Treatment
Authors: Anwar Zahra N , Aznur Laili , Rahmadi Andri R
Published: May 2022

Rheumatoid Arthritis (RA) is a chronic autoimmune disease that causes inflammation of the joints. RA is known to have associations with oral infection. Oral focus infection treatment has been shown to reduce RA disease activity. The Neutrophil-to-Lymphocyte Ratio (NLR) is a parameter to determine the inflammatory activity in RA patients. This study aims to determine the NLR changes of RA patients after oral focus infection treatment. This study is a descriptive and analytic-comparative study using secondary data obtained from the medical records of oral focus infection treated RA patients at Dr. Hasan Sadikin General Hospital, Bandung, from January to December 2019. Data were processed using the Wilcoxon signed-rank test. The data consisted of 17 samples from 3 focus infection categories. A total of 5 samples had a chronic apical infection, 2 samples had a chronic marginal infection, and 10 samples had a chronic apical-marginal infection. The results showed a decrease in median of the NLR after oral focus infection treatment, without statistical significance. In conclusion, there were no significant NLR changes in RA patients who were given oral focus infection treatment.

Keywords: neutrophil-to-lymphocyte ratio; rheumatoid arthritis; oral focus infection
Potential Use of Topical Insulin in Chronic Diabetic Wound Healing
Authors: Wijaya Lorettha , Jawan Erwin
Published: May 2022

Wound healing disturbances that occur in chronic diabetic wounds result in various complications and cause a significant burden. With the increasing prevalence of diabetes mellitus, it is estimated that the numbers of chronic diabetic wounds and their complications will also continue to increase. One of the latest managements using growth factors for chronic diabetic wounds gives satisfactory results, but their use is still limited because of the high costs. This study aims to explore the effectiveness of using topical insulin as a cheaper and effective alternative therapy in chronic diabetic wounds. The method of this study is a literature review sourced from Google Scholar and ProQuest search engine. Eight articles were obtained that are relevant to be discussed in this study. According to studies conducted so far, topical insulin can improve wound healing through the modulation of inflammation and insulin signaling pathways. In conclusion, there is improved wound healing in diabetic chronic wounds patients that were given topical insulin. Therefore topical insulin should be considered as part of chronic diabetic wounds management.

Keywords: wound healing; chronic diabetic wounds; growth factors; topical insulin
Comparison Between Knowledge, Attitude and Participation of Health Care Workers and Civilians at Immanuel Hospital Bandung towards COVID-19 Vaccine
Authors: Widjaja Jahja T , Nathania Evelyn
Published: May 2022

Vaccine for COVID-19 is held with the hope of being the pandemic solution but it also gets various responses from various groups, so researchers want to compare the knowledge, attitudes, and participation of health workers and civilians towards the COVID-19 vaccine. The research design used a cross-sectional study with a total sample of 101 respondents from health workers using simple random sampling and civilians using incidental sampling by time. The data were taken in March-April 2021 using a questionnaire at Immanuel Hospital Bandung. Data analysis used univariate and multivariate analysis. The results showed that 84% of health workers and 83.1% of civilians had good knowledge; 99% of health workers and 93% of civilians are supportive; 89% of health workers and 78.2% of civilians participate in the COVID-19 vaccine. The relationship between knowledge and attitudes has a close relationship (p <0.05), as well as knowledge and participation (p <0.05) and attitudes towards participation (p <0.05) in both civilians and health workers. Both groups have good knowledge, supportive attitude and are willing to participate in the COVID-19 vaccine—the better the knowledge, the better the attitudes and participation. Likewise, the better the attitudes, the more willing they are to participate in the COVID-19 vaccine.

Keywords: vaccine; COVID-19; knowledge; attitude; participation
Difference Uptake of 99mTc-Pyrophosphate vs 99mTc- Methylenediphosphate in Detecting Cardiac Amyloidosis; First Experience in Hasan Sadikin General Hospital
Authors: Marzuki Hadi , Soeriadi Erwin A , Astuti Astri , Budiawan Hendra , Kartamihardja Achmad Hussein S
Published: May 2022

Cardiac amyloidosis (CA) is a disorder caused by deposits of insoluble fibrils in the myocardium and an underdiagnosed cause of heart failure. Immunoglobulin Light Chain-Associated Amyloid (AL) and Amyloidosis Transthyretin-related (ATTR) are the two protein precursors that most commonly cause cardiac amyloidosis.  It is important to distinguish between these two types of amyloidosis because the treatment and prognosis of each types is different. Recent advances in cardiac radionuclide imaging, in particular using bone-seeking agents such as 99mTc-Pyrophosphate (PYP) and 99mTc-Methylenediphosphate (MDP), can differentiate AL from ATTR. This study aimed was to investigate the uptake characteristic of both tracers in CA. Three patients with suspected of having cardiac amyloidosis underwent two cardiac radionuclide imaging examinations using those two different radiopharmaceuticals. The cardiac images were analyzed quantitatively and semi-quantitatively based on ASNC (American Society of Nuclear Medicine) criteria. Cardiac radioactivity uptake of 99mTc-PYP was better from those of 99mTc-MDP based on quantitative as well as semi-quantitative (visual assessment).

Keywords: cardiac amyloidosis; cardiac imaging; 99mTc-PYP; 99mTc-MDP
Peer Review
Authors: Team Editorial
Published: May 2022

We would like to thank our peer reviewers for the precious contributions in providing clinical,scientific, and methodological expertise for JMH Volume 4 Number 1 February 2022. Weappreciate every thoughtful review of submitted manuscripts and for making importantcontributions to improve the scientific quality of articles published in JMH.We listed the names in alphabetical order.Abram Pratama Tanuatmadja, dr., Sp.PD.Adhi Kristianto Sugianli, dr., Sp.PK(K), M.Kes.Andri Rezano, dr., M.Kes, Ph.D.Ardo Sanjaya, dr., M.Kes., Pg.Cert., FHEA.Cindra Paskaria, dr., MKM.Dimas Erlangga Luftimas, dr., M.Kes., Sp.GK.Dr. Fen Tih, dr., M.Kes.Dr. Guswan Wiwaha, dr., MM.Dr. Julia Windi Gunadi, dr., M.Kes.Dr. Titik Respati, drg., MScPH.Dr. Vinna Kurniawati Sugiaman, drg., M.Kes.Grace Puspasari, dr., M.GiziHeddy Herdiman, dr. M.Kes.July Ivone, dr., MKK., MPd.Ked.Ken Edinata, drg., Sp.Ort.Limdawati Kwee, dr., Sp.PD., FPCP.Mia Kusmiati, dr., M.Pd. Ked., Ph.D.Monica Paotiana, dr., M.GiziPenny Setyawati, dr., Sp.PK., M.Kes.Prof. Ahmad Faried, dr., Sp.BS(K)., Ph.D., FICS.
Prof. Wahyuni Lukita Atmadja, dr., Ph.D.Roro Wahyudianingsih, dr., Sp.PA.Susan Irawati, B.Biomed Sc., M.Biomed Sc.Sylvia Mustika Sari, dr., M.Med.Ed., FFRI.Teresa Lucretia, dr., M.Kes.Wawan Kustiawan Jogasuria, dr., Sp.R., M.Kes., DFM.Yuktiana Kharisma, dr., M.Kes.
Kürk Mantolu Madonna adlı romanda toplumsal yaşamda yer edinen kültürel öğelerin KM ve EM’deki yansımalarının karşılaştırmalı olarak incelenmesi
Authors: BAYRAKTAR Sedanur
Published: May 2022

Çeviri, insanlar arasında açık diyaloğun oluşturulmasında hâkim bir rol üstlenmektedir. Varlığa anlam katan kültürel gerçekliklerin, olguların tanımlanmasında çizdiği çerçeve, benzer şekilde farklı kültür dünyalarının birbirlerine açılarak etkileşimde bulunmasına aracılık etmektedir (Taş, 2017). Sözle oluşturulan somut riyazların içtimai yapıya sunduğu katkılar, mütecanis bir bütünün ortaya çıkmasını olanaklı hale getirmekle birlikte, çevirinin öncülüğünde sınırları bertaraf etmektedir. Dilin dinamik yapısını anlama adına, muhtevasına teslim olmak elzemdir. Kültürlerarası iletişimde yazın çevirileri, toplulukların sınırlarını besleyerek, kabulünü artırmaktadır. İşbu sebeple kültürel unsurları çözümlemek, anlamak, yorumlamak ve çevirmek en önemli meseller arasında yer almanın yanı sıra özün tesisinde mühim yenilikleri imal etmektedir. Bu çalışma özelinde Türk edebi literatüründe kalemiyle tanınan saygıdeğer Sabahattin Ali’nin Kürk Mantolu Madonna adlı eseri ile usta çevirmen Ute Birgi tarafından hazırlanan erek metin, Çeviribilimci Peter Newmark’ın kültürel öğelerin sınıflandırması ve Çeviribilim araştırmacısı Lawrence Venuti’nin “yerlileştirme” (domestication) ve “yabancılaştırma” (foreignization) çeviri stratejileri bağlamında karşılaştırmalı olarak incelenecektir. Kültürel öğelerin çevirisinde bu iki çeviri stratejisinden hangisinin daha çok tercih edildiği örnekler kapsamında irdelenerek, çeviri kararlarına açıklık getirilecektir. Çevirinin dönüşüm sürecinde, sınırların kültürel öğelerle anlam dahilinde transferlerinin sağlanması, erek kültürde yeni bir inşayı mümkün kılmakla birlikte işlevsel karşılıklarla anlamsal yakınlığın teminine katkı sunmaktadır. Kültürle içkin olan çeviri eyleminde dilsel olguların yöneldiği yapılar, özgül dizgeler dahilinde mahiyetin anlaşılabilirliğini arttırmaktadır.
Pengaruh Penambahan Konsentrasi Reverse Demulsifi er Terhadap Nilai Oil Content dan Emulsion Block pada Air Injeksi Lapangan Jambi
Authors: Effendi Dahrul , Varayesi Fidya
Published: May 2022

Air injeksi yang digunakan sebagai fl uida pendesak dalam water fl ooding sering ditemukan masalah pada kualitasnya, diantaranya adalah masalah oil content dan emulsion block. karena minyak bertindak sebagai perekat pada padatan yang menyebabkan penyumbatan pada pori- pori batuan. Hal tersebut berpotensi dalam penyebab terjadinya low oil recovery factor pada proses water fl ooding. Air injeksi (IW) dan air formasi (FW) sebelum di injeksikan kedalam reservoir perlu dianalisa dilaboratorium dengan tujuan air injeksi dapat digunakan sebagai fl uida pendesak pada proses water fl ooding. Berdasarkan hasil uji laboratorium, air injeksi (IW) menunjukkan konsentrasi oil content yang tinggi yaitu 50.55 mg/L, sehingga dapat membentuk emulsion block, hal ini dapat mengakibatkan plugging pada pori-pori batuan. Untuk itu, solusi yang dipilih untuk menyelesaikan masalah emulsion block dalam penelitian ini yaitu dengan menggunakan chemical treatment. Masalah oil content dan emulsion block dapat diatasi dengan menggunakan reverse demulsifi er, pada uji di laboratorium dengan menambahkan konsentrasi 50 mg/L reverse demulsifi er kedalam air injeksi dapat meningkatkan kualitas air injeksi dari poor water quality (oil content 50.55 mg/L) menjadi good water quality (oil content 15.89 mg/L).
Identifi kasi Struktur Bawah Permukaan Lapangan Banyuasin dengan Menggunakan Pemodelan 2.5D Data Gravitasi dan Implikasinya Terhadap Petroleum System
Authors: Ramadhani Akbar , Sanjaya Edi , Purba Humbang
Published: May 2022

Lapangan migas Banyuasin bagian utara ditemukan adanya indikasi hidrokarbon di beberapa sumur eksplorasi. Namun, masih belum diketahui bentuk lapisan bawah permukaan, konfi gurasi, dan lokasi tempat batuan sumbernya karena terbatasnya data seismik bawah permukaan. Penelitian ini dilakukan untuk menentukan gambaran bawah permukaan, konfi gurasi, dan lokasi cekungan serta petroleum system nya berdasarkan pemodelan 2.5 D data gravity yang diintegrasikan dengan data seismik. Pemodelan dilakukan dengan metode forward modeling gravity dengan memanfaatkan nilai densitas yang berasal dari data sumur. Berdasarkan hasil interpretasi seismik, log sumur, dan forward modelling gravity, struktur bawah pemukaan daerah penelitian tersusun atas lapisan batuan dasar dengan densitas rata-rata 2.9 gr/cc, lapisan batu serpih Lemat berumur Oligocene dengan densitas rata-rata 2.5 gr/cc, lapisan batupasir Talang Akar berumur sekitaran upper oligocene ke lower Miocene dengan densitas rata-rata 2.4 gr/ cc, lapisan karbonat Baturaja berumur lower Miocene dengan densitas rata-rata 2.6 gr/ cc, lapisan batu serpih telisa berumur middle Miocene dengan densitas rata-rata 2.3 gr/cc, serta lapisan sedimen berumur upper Miocen keatas dengan densitas rata-rata 2-2.3 gr/ cc. Lokasi cekungan berada di sebelah selatan dari lokasi sumur eksplorasi. Hasil analisis petroleum system menunjukkan bahwa hidrokarbon yang berasal dari source rock formasi Lemat bermigrasi kearah reservoir batupasir formasi Talang Akar dan formasi Telisa.
LoRa Modülasyon Tabanlı Saha Aydınlatma Sistemi Uygulaması
Authors: ERKAN Emre , FİDAN Şehmus , OĞRAŞ Hidayet
Published: May 2022

Futbol sahalarının aydınlatılması yeni bir uygulama olmamakla birlikte ilerleyen teknoloji sayesinde yeni geliştirmelere ihtiyaç duyulmaktadır. Özellikle nesnelerin interneti kavramı gün geçtikçe hayatımızda daha fazla yer edinirken aydınlatma ekipmanlarının da bu kapsamda daha teknolojik bir hale getirilmesi kaçınılmazdır. Futbol sahasının aydınlatma seviyesinin değiştirilmesi gereken durumlarda kontrol sinyalleri kablolu veya kablosuz olarak iletilebilir. Ancak futbol sahası aydınlatma projektörlerinde kullanılan LED sürücülerin kontrolü için sinyal kablosu kullanılmasının bazı dezavantajları vardır. Saha aydınlatmasında kullanılan LED sürücülerin sinyal kablolarıyla kontrol edilmesi durumunda, kablo maliyeti, işçilik ve ortamdaki elektriksel gürültülerden etkilenme açısından değerlendirilirse, güvenli ve düşük maliyetli kablosuz sinyal taşımanın önemi net olarak ortaya çıkmaktadır. Bu çalışmada LoRa modülasyon tabanlı kontrol kartları geliştirilmiş ve Diyarbakır ilinde bulunan bir futbol sahasının aydınlatma sistemine uygulanmıştır. Bu sayede kontrol sinyallerinin kablo ile taşındığı sistemlere göre daha düşük maliyetli ve güvenli kablosuz bir sistem kurulmuştur.
Definición y tratamiento del carcinoma basocelular localmente avanzado. Consenso de expertos
Authors: Peñaranda Elkin , Rueda-Cadena Xavier , Ariza-Gómez Santiago Andrés , Medina Iván , Sánchez-Vanegas Guillermo
Published: May 2022

Objetivo: generar recomendaciones basadas en consenso de expertos para el manejo del carcinoma basocelular localmente avanzado (CBCLA) en el contexto colombiano.
Materiales y métodos: se realizó un consenso formal con metodología de grupo nominal. Se llevó a cabo una búsqueda sistemática de la literatura para soportar el desarrollo del consenso de expertos. Se convocó a un grupo de expertos en el manejo del carcinoma basocelular localmente avanzado en Colombia y se estableció un grupo de conducción y un grupo de apreciación (panel de catorce expertos). Se definieron el alcance y las preguntas del consenso. Los grupos trabajaron en reuniones virtuales previas y finalmente en dos espacios presenciales donde se definieron las recomendaciones definitivas.
Resultados: el CBCLA se define como un tumor mayor de 2 centímetros, con compromiso de las estructuras profundas y uno o más de los siguientes criterios: tumor recidivante, bordes mal definidos, agresivo desde el punto de vista histológico y con invasión perineural. Para definir el manejo adecuado, el panel recomendó tener en cuenta los criterios del tumor, de la terapia y del paciente. El panel recomendó que en pacientes con CBCLA, en los que la cirugía no es adecuada, el tratamiento de elección es el vismodegib.
Conclusiones: los resultados del presente trabajo plasman, para el contexto colombiano, la definición de CBCLA y las recomendaciones generales para su manejo, incluidos los aspectos específicos de la terapia médica con vismodegib.
Responsabilidad del médico consigo mismo. Parte 2
Authors: Maya José María
Published: May 2022

El médico tiene responsabilidades éticas con los beneficiarios de su quehacer: los pacientes, los colegas (incluidos otros profesionales de la salud) y la sociedad, pero olvida con frecuencia que tiene responsabilidades para consigo mismo y su familia también. En muchos lugares del mundo, el ser médico ha requerido dedicarse a la práctica de la medicina con muy poca consideración por su propia salud y bienestar. Las semanas de trabajo de 60 a 80 horas son comunes y las vacaciones a veces son consideradas como un lujo innecesario. Aunque muchos médicos parecen vivir bien en estas condiciones, sus familias, sus pacientes, sus colegas y la sociedad pueden verse afectadas desfavorablemente por esta realidad.
Antimycolytic agents: fungistatic and fungicide
Authors: Gudisa Bereda
Published: May 2022

Invasive fungal infections are described as a continuous and severe harm to human health and they are associated with at least 1.5 million deaths worldwide each year. Amphotericin B exerts its activity through hydrophobic interactions with cell membrane ergosterol, cause the rupturing or leakage of cell membrane. The antifungal azole medicine group is classified as imidazoles (clotrimazole, ketoconazole, miconazole) and triazoles (fluconazole, itraconazole, voriconazole, posaconazole, isavuconazole) that are named according to the number of nitrogen atoms in the azole ring. Flucytosine is a first-line treatment for the management of cryptococcal meningitis. The most routine adverse effects of fluconazole involve accelerated liver enzymes, gastrointestinal complaints, headache, and skin rash. If antacids, PPIs, H2 blockers administered together with ketoconazole medicines; they will reduce the blood levels of ketoconazole by increasing gastric pH because ketoconazole requires an acidic media for dissolution and systematic absorption. Griseofulvin ruptures mitotic spindle during metaphase by interacting with fungal microtubules-(-), fungal mitosis (metaphase arrest), adequate to block expansion of fungi (drug is static), preventing them from damaging.
Lip filler with hyaluronic acid - Light Lips Technique
Authors: Natalia Cymrot
Published: May 2022

The lips and perioral region play an important role in facial aesthetics. Aging induces a loss of volume and contour of the lips, a flattening of the cupid's bow, and the appearance of perilabial wrinkles. Thus, aesthetic procedures are common in this area because fillers can reduce these alterations, improving facial harmony. Although the application of the fillers is based on some systematized framework, undesirable results could occur. The Light Lips Technique is a method that applies a very small amount of small-particle hyaluronic acid, only 0.4 ml, to six specific points of the lips. The objective of the technique is to provide lifting of the labial commissures, highlighting some labial points, such as the Glogau-Klein points of the cupid's bow and its equivalent points on the lower lip. After the application of this technique, it is possible to observe an improvement of the lips with very natural-looking results
A round-table discussion to commemorate the centenary of Professor Vsevolod Evgenievich Mamushin’s birth
Authors: Sotova I. A.
Published: May 2022

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A taxonomy of learning outcomes developed for Moscow Electronic School (a case study of individual topics in the Russian language)
Authors: Kuznetsova O. V.
Published: May 2022

The paper examines the issue of designing planned learning outcomes in the process of teaching Russian to school students. This problem became especially relevant after the adoption of the Federal State Educational Standards for primary, basic, and secondary general education. These standards define requirements for personal, meta-subject, and subject-related learning outcomes. Teachers had to respond to the need of specifying planned learning outcomes for an academic year, a topic, an academic period, a lesson taking into consideration the requirements of the system-activity approach as well as different levels of achieving these outcomes by different students. The paper analyses foreign and domestic experience in developing taxonomies for educational purposes and presents the taxonomy of planned learning outcomes developed for Moscow Electronic School. The research is based on theoretical and empirical methods. As a result, planned learning outcomes for the topics included in the course in Russian studied in the fifth form were defined. The obtained results were uploaded to the platform of Moscow Electronic School. Three types of learning outcomes were identified: reproductive, productive, and reflexive. Additionally, the paper describes the possibilities of using the «Planned learning outcomes» service of Moscow Electronic School by teachers. Planned learning outcomes are a methodological tool in teachers’ work. They help to specify lesson objectives, select lesson content, choose the forms of organising students’ activity aimed at producing subject and meta-subject outcomes.
Dialogue with the past: linguo-stylistic analysis of V. G. Rasputin’s short story "French Lessons" (to the 85th anniversary of the birth)
Authors: Ogol’tseva E. V.
Published: May 2022

The relevance of the article is determined by the fact that V. G. Rasputin’s prose is mostly researched from literary and methodological perspectives; less attention is devoted to its linguistic analysis. Despite the abundance of studies focusing on individual aspects of the short story "French Lessons", its holistic linguo-stylistic analysis has not been performed yet. This paper aims to provide a comprehensive description of the linguistic and stylistic specific features of the literary work in question. The research relies on the contextual, aesthetic-stylistic, linguo-poetic methods as well as level-by-level analysis. The paper identified a complex of linguistic means. On the one hand, these means are directed at the sphere of the environment depicted by the writer, and in which the main plot events unfold. On the other hand, they help to create the images of the author, the narrator, and the characters. The paper concludes that V. G. Rasputin made extensive use of lexical phraseological and grammatical means characteristic of the colloquial style to depict "fictional time". The characters’ specific speech features are reflected in the "author’s register" of the narration. The stylistic leitmotif of the story that determines both its composition and its imagery is a complex interaction of different viewpoints (those of the author, the adult narrator, the child-narrator, the characters). "Narrative time" is an amalgamation of colloquial and stylistically neutral means, a frequent occurrence of the adult narrator’s free indirect speech employed to assess the protagonist’s actions and emotions.
Can a textbook bring up a patriot? (Reflections on the upbringing potential of a Russian language textbook)
Authors: Borisenko N. A.
Published: May 2022

The paper considers the upbringing potential of a Russian language textbook, namely the formation of the qualities of citizenship and patriotism in school students. The relevance of the study is determined by the necessity to overcome the spiritual crisis in society as well as by the return of upbringing to school and the implementation of the new «Tentative Program of Upbringing» and the third generation FSES. In accordance with the two documents, upbringing becomes an obligatory part of the teaching process. The paper aims to examine those textbooks on the Russian language that are included in the federal list. This analysis evaluates the potential of such textbooks for patriotic education. The employed methods include theoretical analysis of research literature, analysis of normative documents, and content analysis of five textbooks for fifth-form school students. The presence and absence of materials promoting patriotic education in the textbooks was chosen as criteria for analysis. The materials in question include 1) information about Russian as an official language; 2) statements about the Russian language; 3) representation of Russian symbols; 4) language units comprising the nominative field of the concept «motherland»; 5) exercises revealing the multifaceted image of Russia. The study has identified specific gaps in the content of the textbooks, especially with respect to criteria three and four. The data presented in the paper can serve as a basis for updating textbooks as well as for the work of those teachers who focus on promoting the values associated with patriotism among their students.
Pollution of Airborne Fungi in Naturally Ventilated Repositories of the Provincial Historical Archive of Santiago de Cuba (Cuba)
Authors: Borrego Sofia , Molina Alian , Bonne Yuneisis , González Anyilena , Méndez Lidiersy
Published: May 2022

Environmental fungi can damage the documentary heritage conserved in archives and affect the personnel’s health if their concentrations, thermohygrometric parameters and ventilation conditions are not adequate, problems that can be accentuated by Climate Change. The aims of this work were to identify and to characterize the airborne fungal pollution of naturally ventilated repositories in the Provincial Historical Archive of Santiago de Cuba and predict the risk that these fungi pose to the staff’s health. Indoor air of three repositories of this archive and the outdoor air were sampled in an occasion every time in 2015, 2016 and 2017 using a SAS sampler. The obtained fungal concentrations varied from 135.6 CFU/m3 to 421.1 CFU/m3 and the indoor/outdoor ratios fluctuated from 0.7 to 4.2, evidencing a variable environmental quality over time, but in the third sampling the repositories environments showed good quality. Aspergillus and Cladosporium were the predominant genera in these environments. A. flavus was a prevailed species in indoor air, while A. niger and Cl. cladosporioides were the species that showed the greatest similarities with the outdoor air. Coremiella and Talaromyces genera as well as the species Aspergillus uvarum, Alternaria ricini and Cladosporium staurophorum were the first findings for environments of Cuban archives. Xerophilic species (A. flavus, A. niger, A. ochraceus, A. ustus) indicators of moisture problems in the repositories were detected; they are also opportunistic pathogens and toxigenic species but their concentrations were higher than the recommended, demonstrating the potential risk to which the archive personnel is exposed in a circumstantial way.
Biodegradation of cassava starch modified low density polyethylene by Bacillus cereus and Pseudomonas aeruginosa isolated from waste dumpsite
Authors: CN Mefo  , BA Ezeonuegbu  , JB Ameh  , SA Ado  , US Ishiaku
Published: May 2022

Low density polyethylene (LDPE) is used for packaging and other industrial application is a significant source of environmental pollution. The present study was aimed at testing the ability of bacterial strains identified as Bacillus cereus and Pseudomonas aeruginosa to degrade LDPE. These strains were isolated from soil samples collected from dump site. All bacterial isolates were screened for their ability to degrade synthetic LDPE. Bacillus cereus and Pseudomonas aeruginosa produced weight loss percentages of 0.18% and 0.17% respectively and were used for further studies. The biodegradation was further enhanced by blending pellets of the LDPE (90, 80 and 70 %) with cassava starch (10, 20 and 30%). The screened bacteria isolates were incubated along with the cassava starch modified LDPE for a period of 60 days. Degradation was observed in terms of weight loss and tensile strength of the modified LDPE. Bacillus cereus and Pseudomonas aeruginosa achieved a maximum weight loss reduction of 42.01 % and 51.03 % respectively in LDPE modified with 30 % cassava starch. However, the highest weight loss reduction of 54.03 % in 30 % Cassava starch modified LDPE by the bacterial consortium. Tensile strength of 42.01% was achieved in LDPE containing 30% starch. Therefore these results show that the bacteria used in this study can colonize, utilize and modify LDPE as a sole carbon source, signifying the potential of Bacillus and Pseudomonas spp. to degrade LDPE film. This work would also pave way for future studies on biodegradation to resolve the universal pollution issues.
Ranson criteria for the diagnosis of acute pancreatitis, useful or in disuse?
Authors: Hernando Enrique Thorné Vélez  , Luis Eduardo Pérez Rojas  , Ana María Thorné Vélez  , Natalia Peñaloza Barrios  , Jesús David Ramos Carvajal  , Jose Dario Ortega Gomez  , Paula Andrea Arenas Ruiz  , Eduard Orlando Vargas Plazas  , Bryan Sarmiento Herazo  , Zaira Molina Artunduaga
Published: May 2022

Acute pancreatitis is one of the high-mortality gastrointestinal disorders that requires hospitalization, in this pathology there are various degrees of severity, and it is important to define and stratify them to identify dangerous patients who require aggressive treatment on admission, to identify patients worthy of referral for specialized care and to assign these patients to stratification into subgroups with persistent organ failure and local or systemic complications, the use of scales and criteria is implemented to determine the degree of severity of this and the possible management, among them we find the Ranson criteria, which contribute to the determination of severity, conduct to follow and possible complications, which is usually very useful for the patient's prognosis, but although it is true, the Ranson criteria are simple, easy to remember and very available in any laboratory to carry out ar tests, but they are also limited since they present greater specificity after the first 48 hours of the patient's admission and, in addition, they can be inconclusive because they vary according to the presence or not of a biliary pathology, thus increasing the parameters to be evaluated.
The Police's Effort in Commanding Criminal Acts of Violence in Football Champion
Authors: Pratama Putra Satria Diaz Pratama Putra , Soponyono Eko
Published: May 2022

Cases of violent criminal acts that occurred during football champion in Wonosobo Regency were found in the Wonosobo District Court Decision with case register number 117/Pid.B/2020/PN.WSB with imprisonment for each of 5 (five) months. The method used is juridical empirical research, descriptive research specifications, data sources obtained through secondary and primary data, data collection by literature study and interviews or interviews, qualitative data presentation methods and qualitative data analysis. Based on the results of the study, it was concluded that the panel of judges paid attention to the legal facts as stated in Article 170 paragraph (1) 1 of the Criminal Code, whose elements are: First, the element "whoever", second "openly and collectively", third "using violence against people or goods". Countermeasures by the Wonosobo Police are carried out with penal efforts, namely making arrests, subsequent investigations by transferring the completed case files to the Wonosobo District Attorney for further delegating the case to the Wonosobo District Court for trial. The implementation of non-penal efforts is to coordinate with the organizing committee and carry out escorts during football champion.
The Termination of Middle Criminal Prosecutions based on Restorative Justice
Authors: Sembiring Darma Rejekinta , Kusriyah Sri , Listyawati Peni Rinda
Published: May 2022

The purpose of this study was to find out and analyze how the form and policy of stopping the prosecution of minor crimes through a restorative justice approach and the obstacles faced in implementing the policy of stopping the prosecution of minor crimes through a restorative justice approach. This study used an empirical legal method by relying on primary data sources. Prosecutor's Regulation No. 15 of 2020 concerning Termination of Prosecution Based on Restorative Justice is a breakthrough made by the prosecutor's office to answer legal problems that exist in society, so that punishments that have been considered by the public no longer provide a sense of justice are lost and public trust in the prosecutor's office as part of the public prosecutor's office. Based on the results of the study, it was concluded that of the 80 cases whose prosecution was terminated based on restorative justice referred to above, one of them was carried out by the Demak District Attorney. Although in the implementation of diversion there are obstacles in the form of peace efforts carried out by the Public Prosecutor from the Demak District Prosecutor's Office, the Suspects and Victims have not received a response, but after involving community leaders as mandated in this Perja, peace can be carried out so that a policy is taken to stop the prosecution of the case outside court (before the case is transferred to the Court).
The Criminal Law Policy Regarding the Death Penalty in Renewing of Indonesian Criminal Law
Authors: Alvisahrin Yudi , Soponyono Eko , Ma'ruf Umar
Published: May 2022

This study aims to examine in depth the criminal law policy regarding the death penalty in the renewal of Indonesian criminal law. This research was expected to contribute ideas in the realm of literature in the field of Islamic law as well as input for observers and law enforcers to determine policies related to the death penalty law. To achieve this goal, this research was conducted by observing events or facts deemed relevant to the research, by collecting primary data and secondary data through a juridical-normative approach with qualitative analysis methods. The study with this theme can be concluded that the choice or stipulation of the death penalty as a means to tackle crime is essentially a policy choice. The concept of the draft Criminal Code issues the death penalty from the main criminal system and lists it as a special principal crime or as an exception (special) punishment. These laws are made to maintain the balance of human life in order to create harmony and order.