bluuebunny/crossref_metadata_2025 huggingface dataset:
Is telemonitoring useful for supporting persons with consciousness disorders and caregivers? A preliminary observational study in a real-life population
Authors: Zucchella Chiara , Di Santis Massimo , Ciccone Biagio , Pelella Massimiliano , Scappaticci Marina , Badalassi Giovanna , Lavezzi Susanna , Bartolo Michelangelo
Published: October 2016

Introduction

Preliminary evidences showed that telemedicine may allow a reduction of costs and an enhancement of patients’ satisfaction and quality of life (QoL), with the same effectiveness of conventional methods of healthcare delivery. Literature is quite absent in relation to the use of telemedicine for patients with disorders of consciousness (DoC) whose management is delegated almost entirely to the family. In order to promote an alternative setting to manage persons affected by DoC, also supporting their families, a pilot project was designed to test the feasibility of home-care assistance based on a system of telemonitoring.

Methods

In total, 11 patients were supported by a telemonitoring system via a workstation installed at the patients’ homes. All patients underwent a clinical and functional evaluation at enrolment, after two months, after six months and at the end of the project, after 12 months by means of clinical scales (Glasgow Coma Scale, Rancho Los Amigos Levels of Cognitive Functioning Scale, Glasgow Outcome Scale, Disability Rating Scale), while the World Health Organization (WHO) QoL, the Hamilton Depression Rating Scale, the Hamilton Anxiety Rating Scale and a satisfaction score were completed by caregivers.

Results

Patients’ scores at the clinical scales did not show statistically significant differences from T0 to T3. A trend toward the improvement of caregivers’ QoL, anxiety and depression, as well as a high degree of satisfaction with regard to the intervention, were reported. The economic evaluation showed an average cost/day for a patient of about €70.

Discussion

Preliminary data suggest that the use of telemonitoring services in the management of persons affected by DoC is feasible and well accepted by caregivers, with a potential positive effect on their mood and QoL. Therefore, telemonitoring should be considered in the management of DoC patients to favour discharge from acute care and to support families in home care.
Clinical Results and Mechanical Properties of the Carotid CGUARD Double-Layered Embolic Prevention Stent
Authors: Wissgott Christian , Schmidt Wolfram , Brandt-Wunderlich Christoph , Behrens Peter , Andresen Reimer
Published: October 2016

Purpose: To report early clinical outcomes with a novel double-layer stent for the internal carotid artery (ICA) and the in vitro investigation of the stent’s mechanical properties. Methods: A prospective single-center study enrolled 30 consecutive patients (mean age 73.1±6.3 years; 21 men) with symptomatic (n=25) or high-grade (n=5) ICA stenosis treated with the new double-layer carotid CGUARD Embolic Prevention System (EPS) stent, which has an inner open-cell nitinol design with an outer closed-cell polyethylene terephthalate layer. The average stenosis of the treated arteries was 84.1%±7.9% with a mean lesion length of 16.6±2.1 mm. In the laboratory, 8×40-mm stents where tested in vitro with respect to their radial force during expansion, the bending stiffness of the stent system and the expanded stent, as well as the collapse pressure in a thin and flexible sheath. The wall adaptation was assessed using fluoroscopy after stent release in step and curved vessel models. Results: The stent was successfully implanted in all patients. No peri- or postprocedural complications occurred; no minor or major stroke was observed in the 6-month follow-up. The bending stiffness of the expanded stent was 63.1 N·mm2 and (not unexpectedly) was clearly lower than that of the stent system (601.5 N·mm2). The normalized radial force during expansion of the stent to 7.0 mm, consistent with in vivo sizing, was relatively high (0.056 N/mm), which correlates well with the collapse pressure of 0.17 bars. Vessel wall adaptation was harmonic and caused no straightening of the vessel after clinical application. Conclusion: Because of its structure, the novel CGUARD EPS stent is characterized by a high flexibility combined with a high radial force and very good plaque coverage. These first clinical results demonstrate a very safe implantation behavior without any stroke up to 6 months after the procedure.
Beyond Intellectual Slut Shaming: Traversing Cartesian Dualism, Shame, and Self-Blame in the Neoliberalized Post-Structuralist Critical Classroom
Authors: Perkins Joanna
Published: October 2016

In this article, I conceptualize what I am calling “intellectual slut shaming” and illustrate how such an experience is a naturalized part of neoliberal subjectivity and knowledge production in academia. I will review how Cartesian and neoliberal subjects share several parallel structures, including mind–body dualism, and show how mind–body dualism is connected to the neoliberal experience of intellectual slut shaming. I then turn to one of Descartes’ critical contemporaries, Spinoza, for a powerful critique and expansion of the Cartesian subject. I explore Spinoza’s method of affirmation and how this might be used to ease intellectual slut shaming in the neoliberalist context. To engage in such an affirmative method, I turn to my own autoethnographic accounts in the neoliberal university classroom.
The Responsibilized Consumer: Neoliberalism and English Higher Education Policy
Authors: Morrison Andrew
Published: October 2016

This article considers the function of higher education in England in the responsibilization of young people as consumers of a higher education “product.” The article elaborates a two-part theoretical framework that draws upon Gramsci and Foucault. This framework is then applied to analyze the 2011 White Paper, Students at the Heart of the System. This is examined as an example of technology of neoliberal governance that works at the creation and maintenance of a community of self-reliant consumer-citizens. Significant policy developments subsequent to the 2011 paper are also discussed. The article concludes with the discussion of three issues: I will reflect upon the value of the theoretical framework employed within the study; future policy directions in the higher education sector under the new Conservative administration of 2015 will be considered; I will consider the potential for productive spaces of resistance against the ever-tightening constrictions of educational commercialization and commoditization.
Scripted Fantasies and Innovative Orientalisms: Media, Youth, and Ideology in the Age of the “War on Terror”
Authors: De Lissovoy Noah , Ramaprasad Venkat , Cedillo Stacia , Cook Courtney B.
Published: October 2016

Anxieties associated with global conflict surround youth and ideological narratives mediating these conflicts can be seen in the popular media youth consume. This investigation uses contemporary cultural-theoretical conceptualizations of ideology to analyze several important popular screen-based cultural artifacts created for youth consumption to determine how young audiences are invited into the ideoscapes and discourses of global politics in the age of the “war on terror.” The analysis shows that these youth-oriented media artifacts script fundamental understandings of conflict and provide schema in which young viewers can orient themselves in relation to global Others, while also setting the matrix of intelligibility within which global politics itself becomes coherent. In addition, these popular cultural texts undertake an innovation of familiar Orientalisms, inviting young people to identify with an aggressive defense of the West and serving as an ideological support for the United States in the context of ongoing global conflicts.
In Response to a Call: Evoking a Keynote
Authors: Neilson Alison L. , São Marcos Rita
Published: October 2016

This is an escape from individualism, competition, and transmissive education practices which are the norms within higher education conferences of the neoliberal university. It is built from the script of a video abstract submitted to a call for keynote presenters for an international congress. Using tricksters and poetic presentations, we offer an open work inviting readers to have fun and make meaning from our provocative attempts.
Body as Profession or What Is It With Irma?
Authors: Reinertsen Anne Beate
Published: October 2016

This article is about critical thinking and critique, ultimately quality. It is about becoming (educator) in the urgency of hesitancy and doubt, thus building in creative dense dynamics from the start possibilizing immanent critique practices. I call it material eco/edu/criticism. In our neoliberal rationalisms and times, I indirectly ask questions about the (social) status of hesitancy in both education and research introducing methodological and epistemological concerns into expectations of certainty and knowing hopefully toppling hierarchical expectations and dichotomous notions bringing forth complexity and ambiguousness as strength and a force in our practices: Quality qualia embodied research and teaching and/or body as profession. It is a move from language-based translation to not-only-language-based transduction perhaps and/or simultaneous language and matter assessment literacy. The way I see this—and my desire; this is all about how new materialist approaches can be applied to foster and build cultures of innovation.
A rare cause of hypertension in pregnancy: Phaeochromocytoma
Authors: Shah Sonali , Edwards Lindsay , Robinson Andrew , Crosthwaite Amy , Houlihan Christine , Paizis Kathy
Published: October 2016

A 26-year-old primigravida at 35 weeks’ gestation was transferred to our institution from a regional hospital for management of presumed preeclampsia. Due to the labile nature of her hypertension, further investigation was undertaken which revealed a right-sided phaeochromocytoma. Alpha blockade was commenced, and an uncomplicated elective caesarean delivery was performed at 38 weeks’ gestation under spinal anaesthetic. The patient underwent an elective right laparoscopic adrenalectomy six weeks post-partum. This case highlights the importance of investigating young women for secondary causes of hypertension to avoid mislabelling as essential or gestational hypertension.
Diabetes in pregnancy
Authors: Pettinger Tom , Gray Thomas G. , Gosakan Radhika
Published: October 2016

The prevalence of diabetes mellitus in all of its forms is increasing, but especially type 2 and gestational diabetes due to their association with obesity. Although many will be under the care of a multidisciplinary team, including obstetricians, diabetologists, specialist nurses and dieticians during pregnancy, primary care is the ideal setting for much of the essential pre-pregnancy care and ongoing postnatal support. This is a patient group that can be difficult to manage, especially if there are issues of non-concordance with treatment. The aim of this article is to provide an overview of diabetes in pregnancy, with particular focus on what the best care will look like in general practice. It begins with some background information and continues by looking at each stage of the pregnancy from pre-conceptual advice, through to postnatal and long-term care.
A valuable approach to the use of electronic medical data in primary care research: Panning for gold
Authors: Barnett Stephen , Henderson Joan , Hodgkins Adam , Harrison Christopher , Ghosh Abhijeet , Dijkmans-Hadley Bridget , Britt Helena , Bonney Andrew
Published: October 2016

Background:

Electronic medical data (EMD) from electronic health records of general practice computer systems have enormous research potential, yet many variables are unreliable.

Objective:

The aim of this study was to compare selected data variables from general practice EMD with a reliable, representative national dataset (Bettering the Evaluation and Care of Health (BEACH)) in order to validate their use for primary care research.

Method:

EMD variables were compared with encounter data from the nationally representative BEACH program using χ2 tests and robust 95% confidence intervals to test their validity (measure what they reportedly measure). The variables focused on for this study were patient age, sex, smoking status and medications prescribed at the visit.

Results:

The EMD sample from six general practices in the Illawarra region of New South Wales, Australia, yielded data on 196,515 patient encounters. Details of 90,553 encounters were recorded in the 2013 BEACH dataset from 924 general practitioners. No significant differences in patient age ( p = 0.36) or sex ( p = 0.39) were found. EMD had a lower rate of current smokers and higher average scripts per visit, but similar prescribing distribution patterns.

Conclusion:

Validating EMD variables offers avenues for improving primary care delivery and measuring outcomes of care to inform clinical practice and health policy.
Coming Full Cycle
Authors: Fay Lindsey , Carll-White Allison , Harrell James
Published: October 2016

Purpose:

This article illustrates a collaborative, full cycle diagnostic postoccupancy evaluation (POE) conducted in an emergency department (ED) to demonstrate methods of planning a POE, conducting research to capture meaningful data, and applying outcomes through the use of a design charrette.

Background:

POEs often end with the reporting of findings rather than suggesting how this knowledge feeds forward. A design charrette presents an opportunity to engage with POE evidence and integrate research into practice.

Methods:

Planning for the POE resulted in a multiphased, multimethodological study. Data collection and analysis utilized objective and subjective measures yielding both qualitative and quantitative data. The design charrette then served as an interactive method to assist design practitioners in both understanding and applying the research findings in the redesign of the entry/triage sequence of the ED.

Results:

POE findings revealed four key issues impacting the ED experience. These include workflow, communication, privacy and confidentiality, and safety and security. In analyzing the use of the charrette to link POE findings to design application, it was determined that the charrette should include an all-inclusive, collaborative process, easily interpreted evidence, active participant engagement, and feasible outcomes grounded in research.

Conclusion:

Taking the POE process full cycle is a critical component in bridging the gap between research and its application to design. The charrette process offers a positive mark of completion to the POE and helps participants gain sensitivity to the importance of evidence-based decision-making.
A late presentation of pulmonary valve endocarditis following closure of patent ductus arteriosus in the childhood: A case report
Authors: Trehan Rajeev , Trehan Meena , Eshwarapragada Sharada Venkata
Published: October 2016

Background:

Infective endocarditis is a microbial infection of the endothelial surface of heart and great vessels frequently involving Mitral and Aortic valve. Pulmonary valve endocarditis leading to Severe Pulmonary Regurgitation is extremely rare and is often diagnosed late due to non specificity of symptoms. We intend to report such a case to bring the attention of everyone the long term consequences of Pulmonary Regurgitation. Here we also describe method of replacing Pulmonary valve with Bioprosthetic Aortic valve.

Methods:

We describe the technique of replacement of pulmonary valve with Bioprosthetic Aortic valve in case of severe Pulmonary regurgitation.

Result:

The patient successfully underwent replacement of both Pulmonary and Tricuspid valve with bioprosthetic valve and was discharged from the hospital on seventh post operative day. During successive follow up there was considerable improvement in exercise tolerance and she being presently in NYHA class II.

Conclusion:

Pulmonary valve replacement with bioprosthetic tissue valve should be considered for patients with Pulmonary regurgitation and volume overload of Right ventricle. Emphasis should be on Right ventricle dilatation before setting of RV dysfunction rather then severity of Pulmonary regurgitation alone.
Sociality and Classification: Reading Gender, Race, and Class in a Humorous Meme
Authors: Kanai Akane
Published: October 2016

This article is concerned with how the gendered, raced, and classed practices of readership of a humorous meme on Tumblr organize forms of sociality and belonging along these lines. Based on the anonymous Tumblr blog, WhatShouldWeCallMe, the meme narrates feelings and reactions related to youthful, feminine, Western “everyday” experience through the use of captions and Graphics Interchange Format (GIF) images. Drawing on the feminist Cultural Studies tradition of text-reader analysis as well as New Literacy Studies approaches to literacy, I suggest the practices of readerly participation in the meme require a social rather than individual set of competencies and knowledges. I propose “spectatorial girlfriendship” as a term encompassing how the texts of the meme require the reader to operationalize gendered, classed, and raced classificatory knowledges and construct social forms of commonality on this basis. In the meme, the reader “gets” the joke by aligning an ostensibly incongruous GIF and caption, remixing and matching existing classifications of people, bodies, and objects. I demonstrate how spectatorial girlfriendship as a readerly lens arranges, transacts, and interacts gender, class, and race in multiple ways, indexing social inequalities without recognizing them as such. Bodies in the GIFs become “stock” images, used for selective resignification. Consequently, while offering pleasures of an understood readerly feminine commonality, participation in the meme is structured unequally, going beyond the reader’s ability to decipher the GIF and caption in the posts. The meme privileges an ideal reader constructed through postrace, postfeminist “theories” of the useability of gender, race, and class.
Clot length predicts recanalisation but not outcome after basilar artery occlusion
Authors: van der Hoeven Erik JRJ , Algra Ale , Vos Jan Albert , Mattle Heinrich P , Weimar Christian , Schonewille Wouter J , Kappelle Jaap ,   on behalf of the BASICS registry investigators
Published: October 2016

Introduction

The aim of our study was to evaluate the effect of clot length on both recanalisation and outcome in acute basilar artery occlusion (BAO).

Patients and methods

One hundred forty-nine patients with an acute basilar artery occlusion from the Basilar Artery International Cooperation Study (BASICS) were included. Clot length was assessed on computed tomographic angiography. Thrombus length was divided in tertiles and was related to recanalisation and outcome at 1 month, with Poisson regression. Modified Rankin scale scores of 4 or 5, or death were considered poor outcomes. Additionally, clot length was analysed as a continuous variable.

Results

Forty-nine patients (33%) had a short (4–11 mm), 50 (34%) an intermediate (12–22 mm), and 50 (34%) a long clot (≥23 mm). Multivariable analyses showed a significantly lower probability of recanalisation but no statistically significant difference in poor outcome for patients with a long clot compared with patients with a short clot (RR 0.64, 95% CI: 0.42–0.98 and RR 1.10, 95% CI: 0.88–1.37, respectively). No statistically significant differences were found for patients with an intermediate clot length compared with patients with a short clot length (RR 0.97, 95% CI: 0.75–1.25 and RR 1.11, 95% CI: 0.88–1.40, respectively). Analyses of clot length as a continuous variable showed a 10% reduction in chance of recanalisation and a 2% increase in risk of poor outcome with every centimeter increase in clot length (RR 0.90, 95% CI: 0.78–1.04 and RR 1.02, 95% CI: 0.98–1.05, respectively).

Conclusions

Clot length predicted recanalisation but not outcome at 1 month in patients with a BAO. We found 2% more poor outcome and 10% less recanalisation with every centimeter increase in clot length.
A role for autophagy in carotid atherosclerosis
Authors: Alloza Iraide , Goikuria Haize , Freijo María del Mar , Vandenbroeck Koen
Published: October 2016

Purpose

Autophagy has emerged in recent years as a critical cellular survival mechanism for cell homeostasis and may play a protective role in atherosclerosis. We aimed to review here the role autophagy plays in different cell types present in carotid atherosclerotic plaques and that may be associated with the development of unstable carotid atheroma plaque.

Methods

We performed a thorough literature exploration in this area of research covering the three main cell types present in carotid atheroma plaques.

Findings

Reviewed reports indicate that the role of autophagy in stable or unstable carotid atherosclerotic plaques depends on the different cell types and phenotypes, the stage and morphology of the plaque and the specific autophagy factor/s involved.

Discussion

Although defective autophagy could be one of the causes for carotid atheroma plaques to become unstable, it is important to take into account that autophagic players can act differentially in different cell types and different stages of the developed plaque.

Conclusion

This review provides an overview of the role of autophagy in the main cell types in carotid atherosclerosis (i.e. macrophages, endothelial cells and smooth muscle cells).
Draft genome sequence of the marine Rhodobacteraceae strain O3.65, cultivated from oil-polluted seawater of the Deepwater Horizon oil spill
Authors: Giebel Helge-Ansgar , Klotz Franziska , Voget Sonja , Poehlein Anja , Grosser Katrin , Teske Andreas , Brinkhoff Thorsten
Published: October 2016

The marine alphaproteobacterium strain O3.65 was isolated from an enrichment culture of surface seawater contaminated with weathered oil (slicks) from the Deepwater Horizon (DWH) oil spill and belongs to the ubiquitous, diverse and ecological relevant Roseobacter group within the Rhodobacteraceae. Here, we present a preliminary set of physiological features of strain O3.65 and a description and annotation of its draft genome sequence. Based on our data we suggest potential ecological roles of the isolate in the degradation of crude oil within the network of the oil-enriched microbial community. The draft genome comprises 4,852,484 bp with 4,591 protein-coding genes and 63 RNA genes. Strain O3.65 utilizes pentoses, hexoses, disaccharides and amino acids as carbon and energy source and is able to grow on several hydroxylated and substituted aromatic compounds. Based on 16S rRNA gene comparison the closest described and validated strain is Phaeobacter inhibens DSM 17395, however, strain O3.65 is lacking several phenotypic and genomic characteristics specific for the genus Phaeobacter. Phylogenomic analyses based on the whole genome support extensive genetic exchange of strain O3.65 with members of the genus Ruegeria, potentially by using the secretion system type IV. Our physiological observations are consistent with the genomic and phylogenomic analyses and support that strain O3.65 is a novel species of a new genus within the Rhodobacteraceae.
Cell-autonomous stress responses in innate immunity
Authors: Moretti Julien , Blander J Magarian
Published: October 2016

The innate immune response of phagocytes to microbes has long been known to depend on the core signaling cascades downstream of pattern recognition receptors (PRRs), which lead to expression and production of inflammatory cytokines that counteract infection and induce adaptive immunity. Cell-autonomous responses have recently emerged as important mechanisms of innate immunity. Either IFN-inducible or constitutive, these processes aim to guarantee cell homeostasis but have also been shown to modulate innate immune response to microbes and production of inflammatory cytokines. Among these constitutive cell-autonomous responses, autophagy is prominent and its role in innate immunity has been well characterized. Other stress responses, such as metabolic stress, the ER stress/unfolded protein response, mitochondrial stress, or the DNA damage response, seem to also be involved in innate immunity, although the precise mechanisms by which they regulate the innate immune response are not yet defined. Of importance, these distinct constitutive cell-autonomous responses appear to be interconnected and can also be modulated by microbes and PRRs, which add further complexity to the interplay between innate immune signaling and cell-autonomous responses in the mediation of an efficient innate immune response.
Dynamic interactions between dermal macrophages and Staphylococcus aureus
Authors: Feuerstein Reinhild , Kolter Julia , Henneke Philipp
Published: October 2016

The dermis, a major reservoir of immune cells in immediate vicinity to the colonizing skin microflora, serves as an important site of host-pathogen interactions. Macrophages (Mϕ) are the most frequent resident immune cell type in the dermis. They protect the host from invasive infections by highly adapted bacteria, such as staphylococci via pattern recognition of bacterial effectors, phagocytosis, and recruitment of other myeloid cells from the blood. Already under homeostatic conditions, the dermal Mϕ population receives a dynamic input of monocytes invading from the bloodstream. This quantitative renewal is promoted further at the beginning of life, when prenatally seeded cells are rapidly replaced and in healing phases after injuries or infections. Here, we discuss the potential implications of the dynamic dermal Mϕ biology on the establishment and maintenance of immunity against Staphylococcus aureus, which can either be a harmless colonizer or an invasive pathogen. The understanding of the heterogeneity of the “mature” dermal Mϕ compartment driven both by the influx of differentiating monocytes and by a bone marrow-independent Mϕ persistence and expansion may help to explain failing immunity and immunopathology originating from the skin, the important interface between host and environment.
Synovial IL-21/TNF-producing CD4+ T cells induce joint destruction in rheumatoid arthritis by inducing matrix metalloproteinase production by fibroblast-like synoviocytes
Authors: Lebre Maria C , Vieira Pedro L , Tang Man Wai , Aarrass Saïda , Helder Boy , Newsom-Davis Thomas , Tak Paul P , Screaton Gavin R
Published: October 2016

Bone and cartilage destruction is one of the key manifestations of rheumatoid arthritis (RA). Although the role of T helper (Th)17 cells in these processes is clear, the role of IL-21–producing cells T cells has been neglected. We sought to investigate the role of IL-21 in RA by focusing on the functional characteristics of the main producers of this cytokine, synovial CD4+IL-21+ T cells. We show that the frequency of both synovial fluid (SF) CD4+IL-21+ or CD4+IL-21+TNF+ T cells in patients with RA was significantly higher compared with patients with psoriatic arthritis (PsA). The frequency of peripheral blood (PB) IL-21+CD4+ T cells in patients with RA positively correlated with disease activity score 28 (DAS28), serum anticyclic citrullinated peptide (anti-CCP) antibodies and IgM-rheumatoid factor (IgM-RF). IL-21 levels in RA SF were associated with matrix metalloproteinase (MMP)-1 and MMP-3. Related to this, IL-21 induced significantly the secretion of MMP-1 and MMP-3 in RA synovial biopsies. Sorted SF CD4+IL-21+ T cells significantly induced the release of MMP-1 and MMP-3 by fibroblast-like synoviocytes (FLS) compared with medium or CD4+IL-21− T cells in a coculture system. Neutralization of both IL-21 and TNF resulted in significantly less production of MMP by FLS. The results of this study indicate a new role for synovial CD4+IL-21+TNF+ T cells in promoting synovial inflammation/joint destruction in patients with RA. Importantly, IL-21 blockade in combination with anti-TNF might be an effective therapy in patients with RA by inhibiting MMP-induced inflammation/joint destruction.
Massive ear keloids: Natural history, evaluation of risk factors and recommendation for preventive measures – A retrospective case series
Authors: Tirgan Michael
Published: October 2016

Keloid disorder (KD) is an inherited wound healing ailment, frequently seen among Africans /African Americans and Asians.  Genetics of this disorder continues to be obscure and poorly understood.  Clinical manifestation of KD is quite variable and very diverse, spanning from individuals with one or very few small keloidal lesions, to those with numerous and very large lesions covering large portion of their skin. Ears are common locations for development of keloids.  Ear piercing is by far the leading triggering factor for ear keloid formation in genetically predisposed individuals. Although there are numerous publications about ear and earlobe keloids, there is a void in medical literature about massive ear keloids.  This paper focuses on the natural history of massive ear keloids and risk factors that lead to formation of these life-changing and debilitating tumors and recommendations for prevention.
Modern Problems of Functioning of Small Business in Russia
Authors: Суворова  , Suvorova M. , Суджаева  , Sudzhaeva G.
Published: October 2016

This article is devoted to research of problems of functioning of small business in Russia in modern conditions. There are several factors constraining the development of small and average business in Russia. The article describes the main mechanisms and tools of state support of small and average business in Russia, as well as the effect from their application. The experience of formation and functioning of small and medium businesses foreign countries is described.
A New Model of Small Business Organization
Authors: Жуков  , Zhukov R.
Published: October 2016

In terms of Government action aimed at ensuring sustainable socio-economic development of the Russian Federation in 2016 22 points are devoted to the situation of small and medium enterprises. However, funding is one-sided. In this connection, the necessity of creation of the state franchise system is justified. A sequence of implementation and the effects of state franchise system on the Russian economy is considered.
Anticipated Regret and Product Innovation
Authors: Jiang Baojun , Narasimhan Chakravarthi , Turut Özge
Published: October 2016

When a firm introduces a product with new features, some consumers may find it difficult to assess their valuations for these new attributes. Their purchase decisions made under such uncertainty may lead to postpurchase regret. It has been experimentally shown that consumers may anticipate their potential postpurchase regret and make their current choices to mitigate or minimize it. That is, a consumer’s anticipated regret can significantly impact his purchase decision. Given the trend that firms in various markets invoke regret to stimulate sales, this paper analytically explores whether and how anticipated regret affects competing firms’ profits and product innovation. Our analyses reveal that the presence of anticipated regret can increase or decrease firms’ profits, and foster or hinder product innovation depending on whether it makes the consumer segments more or less polarized; in other words, anticipated regret has a nonmonotonic effect on firms’ profits and the entrant’s optimal quality. Therefore, anticipated regret may sometimes create a win-win or a lose-lose situation for both firms. Regardless of whether the impact of anticipated regret on firms’ profits is positive or negative, the magnitude of that impact tends to be higher for the low-quality firm.

This paper was accepted by J. Miguel Villas-Boas, marketing.
Modeling, Analysis, and Design Insights for Shuttle-Based Compact Storage Systems
Authors: Tappia Elena , Roy Debjit , de Koster René , Melacini Marco
Published: October 2016

Shuttle-based compact systems are new automated multideep unit-load storage systems with lifts that can potentially achieve both low operational cost and large volume flexibility. In this paper, we develop novel queuing network models to estimate the performance of both single-tier and multitier shuttle-based compact systems. Each tier is modeled as a multiclass semi-open queuing network, whereas the vertical transfer is modeled using an open queue. For a multitier system, the models corresponding to tiers and vertical transfer are linked together using the first and second moment information of the queue departure processes. The models can handle both specialized and generic shuttles and both continuous and discrete lifts. The accuracy of the models is validated through both simulation and a real case. Errors are acceptable for conceptualizing initial designs. Numerical studies provide new design insights. Results show that the best way to minimize expected throughput time in single-tier systems is to have a depth/width ratio around 1.25. Moreover, specialized shuttles are recommended for multitier systems because the higher cost of generic shuttles is not balanced by savings in reduced throughput time and equipment needs.
Malnutrition screening in acutely unwell elderly inpatients
Authors: Sharma Yogesh , Miller Michelle , Shahi Rashmi , Hakendorf Paul , Horwood Chris , Thompson Campbell
Published: October 2016

Background: The rate of malnutrition among hospitalised elderly patients in Australia is 42.3%. Malnutrition is known to lead to significant adverse outcomes for the patients and increase hospital costs through increased use of resources. Aim: This study assessed nutrition screening adequacy and investigated factors associated with missed opportunity to diagnose malnutrition. Methods: A prospective cross-sectional study involving 205 general medical patients aged ≥60 years admitted acutely in a tertiary hospital over a period of 1 year. Patients who were not given initial nutritional screening were noted and all patients underwent nutritional assessment. The researchers assessed demographic data and performed univariate analysis of factors responsible for missed nutritional screening. Results: Only 99 patients (49.5%) were screened for malnutrition and 100 (50.3%) missed initial nutritional screening (data incomplete for 6 patients). Of those screened, more were malnourished (n=64; 61.5%) than those not screened (n=40; 38.5%), p<0.001. There was no significant difference in screening rates over the weekends and public holidays compared with weekdays (p=0.14). Time of day (p=0.03) and ward location (p=0.001) were significant factors, which determined nutrition screening. Conclusion: This study indicates common associations that might explain low inpatient screening rates for malnutrition; these include apparently adequate nutritional status, lower staff to patient ratios and outlier ward locations. Ensuring consistent nutrition screening with appropriate therapeutic interventions for patients and educational interventions for staff could pay dividends not only in terms of improved patient health but also in terms of hospital reimbursement.
House, home and transforming energy in a cold climate
Authors: Webb Janette , Hawkey David , McCrone David , Tingey Margaret
Published: October 2016

Warm homes are fundamental to a sense of personal security and citizenship, but many lowincome families and households struggle to pay their energy bills, and energy prices are caught up in the politics of welfare and climate change. Our research uses a sociological perspective to investigate the experiences of low-income households, on a Glasgow housing estate, living through a major renovation programme to insulate homes and install community heating. The Housing Association’s aim was to combine amelioration of fuel poverty with reduced greenhouse gas emissions. We examine the complex results from the renovation, which indicate that the UK economistic model of households as primarily consumers limited, rather than facilitated, the achievement of desired co-benefits for welfare and environment. We show the centrality of personal and domestic relationships to the future of affordable, secure and clean energy. We suggest that social scientists have an important contribution to public understanding of connections between families and relationships, localities and the politics of energy and environment.
The Attentive Creator of Contemporary Rituals
Authors: Tomažin Irena
Published: October 2016

In her book Conversations with Meredith Monk, Bonnie Marranca publishes four conversations that occurred between 2008 and 2013, that is, in Monk’s mature period of creation, hence affording the artist occasion to reflect on her past work. Among other things, she affirms that her relationship to her work is informed by her practice of Buddhism. She refers to directorial method of “weaving” together the different media she uses when constructing her stage works, allowing her to connect the different worlds contained within different media and in so doing experience herself as an integrated being. She describes the creation of a work as the search for something fundamental, understanding each work as its own world, which she listens to and whose laws she searches for in an uninterrupted dialogue with the work as the subject. For her, the stage is a holy space, a space for ritual between performers and audience, in which an important role is played by shared time, unrepeatable and transient. The conversations with Monk reveal how her creative process heeds the internal desires of the creation and simultaneously ignores the instructions of established aesthetic guidelines.
Become the Ideal Cultural Worker in 86 Steps – A Handbook
Authors: Arhar Nika , Brezavšček Pia , Čičigoj Katja , Rakef Saška , Založnik Jasmina
Published: October 2016

Be a revolutionary. Demand the impossible. Be transgressive and provocative. Always do one more thing than you can do. Always do more than you can. Always do more… a handbook that will tell you, in 86 steps, how to become a model self-employed cultural worker in late capitalism.
COMPETÊNCIAS DA ORGANIZAÇÃO INOVADORA: UM ESTUDO EM EMPRESAS DO INSTITUTO PAULISTA DE EXCELÊNCIA DA GESTÃO E FUNDAÇÃO NACIONAL DA QUALIDADE
Authors: Baraldi Adriana , Vasconcellos Marcos Augusto de , Di Serio Luiz Carlos , Pereira Silvana Marques dos Santos , Prim Alexandre Luis
Published: October 2016

Gerir a inovação tem sido o desafio de boa parte das organizações, uma vez que demanda competências específicas às empresas que quando bem geridas podem significar ganho competitivo, mas quando não podem representar estagnação e perda de mercado. Com base nisso, o artigo tem como objetivo identificar lacunas na gestão de inovação de empresas do Instituto Paulista de Excelência da Gestão e da Fundação Nacional da Qualidade com base na metodologia do Fórum de Inovação da FGV/EAESP, que tem como base cinco competências da organização inovadora: liderança e intenção estratégica; meio inovador interno; pessoas; processos de inovação; e resultados. Para tanto, foi realizado um estudo quantitativo. O método de pesquisa adotado foi a survey. Como análise estatística foi realizada análise fatorial confirmatória, purificação dos dados, de acordo com os indicadores de confiabilidade, análise do modelo estrutural e análise de regressão. Foi enviado questionário online para todas as empresas do Instituto Paulista de Excelência da Gestão e da Fundação Nacional da Qualidade e obtido um total de 93 respostas válidas. Os resultados demonstraram que as competências “meio inovador”, “pessoas” e “processos” são responsáveis pelo desempenho obtido na competência “resultado”. Apenas a “liderança” não apareceu como determinante do resultado. Como contribuição, o artigo chama a atenção para a dificuldade das organizações gerarem resultado de inovação e o coloca como consequência de competências que o antecedem.
RECURSOS ESTRATÉGICOS PARA VANTAGEM COMPETITIVA SUSTENTÁVEL EM FOOD TRUCKS
Authors: Hoffmann Valmir Emil , Leonelo Arthur Malimpense , Dias Cleidson Nogueira , Matias Isaac
Published: October 2016

O Food Truck chegou recentemente no Brasil e devido o relevante papel socioeconômico das Micro e Pequenas Empresas (MPE) faz-se necessário compreender melhor esse tipo de empreendimento. Para isso aplicou-se a Visão Baseada em Recursos (VBR). O presente estudo tem como objetivo identificar os recursos que são a fonte de vantagem competitiva sustentável possibilitando aos Food Trucks desempenho acima da média. A pesquisa é qualitativa e de caráter descritivo, tendo como método o estudo de caso e a coleta de dados foi por meio de entrevistas semiestruturadas e observação. O estudo revelou que o conjunto de recursos geradores de vantagem competitiva é variado dentro das organizações pesquisadas. Assim, os recursos que mais se destacaram como potenciais geradores de vantagem competitiva sustentável foram: modelo do truck, matéria-prima exclusiva, geração de energia, equipamentos, network, conhecimento técnico dos funcionários, bom atendimento, receita própria, reputação da empresa e investimentos, cujo bom atendimento foi o único recurso estratégico comum às quatro empresas estudadas.
INFLUÊNCIAS DO DIREITO AMBIENTAL NOS DIREITOS INDÍGENAS
Authors: De Bom de Souza Alisson , Weissheimer Loreno
Published: October 2016

Este artigo discute a aplicação do direito ambiental e do paradigma da sustentabilidade nos direitos dos índios previstos na Constituição da República Federativa do Brasil de 1988. Para tanto, apresentam-se noções gerais do direito dos índios à diferença, bem como sobre direito ambiental e sustentabilidade. O objetivo é analisar a influência do direito ambiental nas terras tradicionalmente ocupadas pelos índios, verificando potenciais conflitos e indicando a aproximação entre sustentabilidade e terras indígenas. A metodologia aplicada é a indutiva. Utiliza-se, também, as técnicas do referente, da categoria, do conceito operacional e da pesquisa bibliográfica.
O DIREITO PENAL COMO INSTRUMENTO DESTINADO À PROTEÇÃO DO MEIO AMBIENTE: ANÁLISE NO CONTEXTO DA CONSTITUIÇÃO FEDERAL BRASILEIRA
Authors: Viviani Rodrigo Andrade
Published: October 2016

O presente artigo tem por objetivo expor a relevância e necessidade da intervenção do Direito Penal para proteger o meio ambiente no contexto do ordenamento jurídico brasileiro, especialmente levando em consideração os riscos desencadeados na sociedade contemporânea, provenientes do progresso tecnológico e industrial. Para tanto, utilizando-se o método indutivo, pretende-se abordar, inicialmente, a estrutura normativa constitucional a respeito do meio ambiente, inclusive apontando a sua natureza de direito fundamental. A partir disso, pretende-se discorrer sobre a importância da intervenção penal na esfera ambiental, que teria um caráter de prevenção, contribuindo, sobretudo, com a educação ambiental. Ao final, conclui-se que o Direito Penal, em razão dos novos interesses inerentes à sociedade pós-industrial, mostra-se uma visa adequada e necessária para proteger o meio ambiente.
An investigation of university students’ homophobia levels regarding gender and gender roles
Üniversitesi öğrencilerinin homofobi düzeylerinin cinsiyet ve cinsiyet rolleri açısından incelenmesi
Authors: Sanberk İsmail , Çelik Metehan , Gök Mehmet
Published: October 2016

The aim is to examine the investigation whether gender, gender role and both of them is effective on the homophobia levels among the university students or not. The sample includes 202 girls (63%) and 118 men (37%), total rate 320 students from different departments of Çukurova Univercity. The data is collected through Personal Information Form, Bem Gender Role Invantory and Hudson Ricket Homophobia Scale. The findings reflect that university students’ homophobia levels differ significantly in terms of gender and gender roles. It means that, those men and masculine gender role they have received from homophobia scale scores were significantly higher. However, the gender and the role of gender have not been found to play a significant role on the common effects of homophobia. Özet Bu çalışmanın amacı üniversite öğrencilerinin cinsiyet, cinsiyet rolleri ve her iki değişkenin homofobi düzeyi üzerinde, ortak etki gösterip göstermediğini incelemektir. Araştırmanın örneklemini Çukurova Üniversitesinin farklı bölümlerinde öğrenim gören 202’si kız (%63) ve 118’i erkek (%37) olmak üzere toplam 320 öğrenci oluşturmuştur. Veriler Kişisel Bilgi Formu, Bem Cinsiyet Rolü ve Hudson ve Ricket Homofobi Ölçekleri aracılığıyla toplanmıştır. Elde edilen bulgular üniversite öğrencilerinin homofobi puanlarının cinsiyet ve cinsiyet rolü açısından anlamlı düzeyde farklılaştığını göstermektedir. Buna göre erkekler ve cinsiyet rolü erkeksi olanların homofobi ölçeğinden aldıkları puanlar anlamlı düzeyde daha yüksek bulunmuştur. Ancak cinsiyet ve cinsiyet rolü ortak etkisinin homofobi üzerinde anlamlı rol oynamadığı tespit edilmiştir.
Hydra group doubles are not residually finite
Authors: Pueschel Kristen
Published: October 2016

In 2013, Kharlampovich, Myasnikov, and Sapir constructed the first examples of finitely presented residually finite groups with large Dehn functions. Given any recursive function
Change of Multiple-Layered Phospholipid Vesicles Produced by Electrostatic Deposition of Polymers during Storage
Authors: Chun Ji-Yeon , Weiss Jochen , Gibis Monika , Choi Mi-Jung , Hong Geun-Pyo
Published: October 2016

In this study, 1 wt% lecithin (–), chitosan (+), and λ-carrageenan (–) were prepared to manufacture multiple-layered liposomes with optimal formulations developed in a previous study by using layer-by-layer electrostatic deposition. We observed their particle size, ζ-potential, sedimentation behavior, and microstructure for 6 weeks. Multiple-layered liposomes were quenched with calcein to evaluate stability in terms of factors such as encapsulation efficiency and released amount of calcein. The particle size of multi-layered liposomes increased with storage periods and the ζ-potential of multiple-layered liposomes gained a neutral charge. Interestingly, negatively charged layered liposomes were smaller than positively charged layered liposomes and showed a lower polydispersity index. Moreover, the ζ-potential did not apparently change compared to positively charged layered liposomes. For the calcein release study, multiple-layered liposomes significantly sustained quenched calcein more than that observed using non-layered liposomes. This study showed that it was possible to increase the thickness of the liposome surface and to manipulate its charge using chitosan and λ-carrageenan through electrostatic deposition. Results showed that manufacturing negatively charged multiple-layer (over 4-layer) liposomes with charged biopolymer improved the physicochemical stability of liposomes.
Transformative Poetry. A Case Study of W. H. Auden’s Musée Des Beaux Arts and General Conclusions
Authors: Sarot Marcel
Published: October 2016

This article situates Auden’s poem Musée des Beaux Arts in the process of his conversion to Christianity. The author argues for the layered intertextuality of the poem, in which allusions to Bruegel’s Landscape with the Fall of Icarus, The Census at Jerusalem, and The Massacre of the Innocents can be recognised. Moreover, Philippe de Champaigne’s Presentation in the Temple and Peter Paul Rubens’s The Martyrdom of St Livinus (in the same museum in Brussels) seem also to have influenced the poem. Finally, there is reason to suppose that John Singer Sargent’s Crashed Aeroplane influenced Auden. In an analysis of the structure of the poem, the author argues that there is a clear structure hidden under the surface of day-to-day language. He connects this hidden structure with Auden’s poem The Hidden Law, and suggests that Auden wished to claim that even though we cannot understand suffering, it has a hidden meaning known only to God. This hidden meaning connects our suffering with the self-emptying of Christ, a connection which the author demonstrates is in fact also made in Musée des Beaux Arts.