bluuebunny/crossref_metadata_2025 huggingface dataset:
Retrospective Analysis of Geriatric Major Trauma Patients Admitted in the Shock Room of a Swiss Academic Hospital: Characteristics and Prognosis
Authors: Pagin Monica , Mabire Cédric , Cotton Michael , Zingg Tobias , Carron Pierre-Nicolas
Published: May 2020

Increased life expectancy exposes a great number of elderly people to serious accidents, thus increasing the amount of major geriatric trauma cases. The aim of our study was to determine the profile of elderly patients undergoing major trauma, and the contributing factors predicting mortality in this specific patient group, compared to the younger population. Retrospective analysis of 1051 patients with major trauma admitted over ten years in a Level-1 trauma center was performed. Data collected were: history, nature and type of trauma; age and sex; vital signs on admission; injury severity score; shock index; comorbidities; coagulation diathesis; injury patterns; emergency measures taken; main diagnosis; mortality; and length of hospital and intensive care unit (ICU) stay. Geriatric patients admitted for major trauma have a mortality rate almost four times greater (47%) than their younger counterparts (14%) with the same ISS. According to statistical regression analysis, anti-platelet therapy (OR 3.21), NACA (National Advisory Committee for Aeronautics) score (OR 2.23), GCS (OR 0.83), ISS (OR 1.07) and age (OR 1.06) are the main factors predicting mortality. Conclusion: Geriatric major trauma patients admitted to our trauma resuscitation area have a high mortality rate. Age, GCS, ISS and NACA scores as well as anti-platelet therapy are the main factors predicting mortality.
Glycoprotein Profile Assessed by 1H-NMR as a Global Inflammation Marker in Patients with HIV Infection. A Prospective Study
Authors: Malo Ana-Irene , Rull Anna , Girona Josefa , Domingo Pere , Fuertes-Martín Rocío , Amigó Núria , Rodríguez-Borjabad Cèlia , Martínez-Micaelo Neus , Leal Manuel , Peraire Joaquim , Correig Xavier , Vidal Francesc , Masana Lluis
Published: May 2020

Plasma glycoproteins are a composite biomarker of inflammation and can be detected by 1H-NMR. The aim of this study was to prospectively appraise the clinical value of plasma glycoproteins assessed by 1H-NMR in people living with HIV (PLWH). A total of 221 patients with HIV infection were recruited and studied at baseline and at 48 and 144 weeks. Patients were distributed into two groups according to baseline CD4+ T-cell number below or above 200 cells/µL. Patients with fewer than 200 cells/µL were distributed into the responders and nonresponders according to antiretroviral therapy (ART) response at 144 weeks. Glycoprotein concentrations were determined by 1H-NMR arising from the protein bond N-acetylglucosamine and N-acetylgalactosamine signals (GlycA); and N-acetylneuraminic acid signal (GlycB) associated with the sugar–protein bond concentration and aggregation state (shapes (height/width)). Basal glycoprotein concentrations were higher in patients with < 200 CD4+ T-cell/μL (Glyc A: 1040(917.9–1199.1) vs. 950.4(845.5–1050.9), p < 0.001, and Glyc B: 521(440.3–610.3) vs. 468.6(417.9–507.0) μ mol/L, p < 0.001) being reduced by ART. The height/width (H/W) ratio was the parameter showing a better association with this clinical status. Baseline glycoproteins predict the condition of responder/nonresponder. In this study, 1H-NMR glycoproteins provide novel insights to assess inflammation status and have prognostic value in PLWH.
Chronic Kidney Disease Management in General Practice: A Focus on Inappropriate Drugs Prescriptions
Authors: Barbieri Maria Antonietta , Rottura Michelangelo , Cicala Giuseppe , Mandraffino Rossella , Marino Sebastiano , Irrera Natasha , Mannucci Carmen , Santoro Domenico , Squadrito Francesco , Arcoraci Vincenzo
Published: May 2020

Nephrotoxic drugs prescriptions are often prescribed inappropriately by general practitioners (GPs), increasing the risk of chronic kidney disease (CKD). The aim of this study was to detect inappropriate prescriptions in patients with CKD and to identify their predictive factors. A retrospective study on patients with creatinine values recorded in the period 2014–2016 followed by 10 GPs was performed. The estimated glomerular filtration rate (eGFR) was used to identify CKD patients. The demographic and clinical characteristics and drugs prescriptions were collected. A descriptive analysis was conducted to compare the characteristics and logistic regression models to estimate the predictive factors of inappropriate prescriptions. Of 4098 patients with creatinine values recorded, 21.9% had an eGFR <60 mL/min/1.73 m2. Further, 56.8% received inappropriate prescriptions, with a significantly lower probability in subjects with at least a nephrologist visit (Adj OR 0.54 (95% CI 0.36–0.81)) and a greater probability in patients treated with more active substances (1.10 (1.08–1.12)), affected by more comorbidities (1.14 (1.06–1.230)), or with serious CKD (G4/G5 21.28 (7.36–61.57)). Nonsteroidal anti-inflammatory drugs (NSAIDs) were the most used contraindicated drugs (48.5%), while acetylsalicylic acid was the most inappropriately prescribed (39.5%). Our results highlight the inappropriate prescriptions for CKD authorized by GPs and underline the need of strategies to improve prescribing patterns.
Metabolome–Microbiome Crosstalk and Human Disease
Authors: Lee-Sarwar Kathleen A. , Lasky-Su Jessica , Kelly Rachel S. , Litonjua Augusto A. , Weiss Scott T.
Published: May 2020

In this review, we discuss the growing literature demonstrating robust and pervasive associations between the microbiome and metabolome. We focus on the gut microbiome, which harbors the taxonomically most diverse and the largest collection of microorganisms in the human body. Methods for integrative analysis of these “omics” are under active investigation and we discuss the advances and challenges in the combined use of metabolomics and microbiome data. Findings from large consortia, including the Human Microbiome Project and Metagenomics of the Human Intestinal Tract (MetaHIT) and others demonstrate the impact of microbiome-metabolome interactions on human health. Mechanisms whereby the microbes residing in the human body interact with metabolites to impact disease risk are beginning to be elucidated, and discoveries in this area will likely be harnessed to develop preventive and treatment strategies for complex diseases.
Periodic DFT Calculations—Review of Applications in the Pharmaceutical Sciences
Authors: Mazurek Anna Helena , Szeleszczuk Łukasz , Pisklak Dariusz Maciej
Published: May 2020

In the introduction to this review the complex chemistry of solid-state pharmaceutical compounds is summarized. It is also explained why the density functional theory (DFT) periodic calculations became recently so popular in studying the solid APIs (active pharmaceutical ingredients). Further, the most popular programs enabling DFT periodic calculations are presented and compared. Subsequently, on the large number of examples, the applications of such calculations in pharmaceutical sciences are discussed. The mentioned topics include, among others, validation of the experimentally obtained crystal structures and crystal structure prediction, insight into crystallization and solvation processes, development of new polymorph synthesis ways, and formulation techniques as well as application of the periodic DFT calculations in the drug analysis.
Glyceraldehyde-3-phosphate Dehydrogenase Is a Multifaceted Therapeutic Target
Authors: Lazarev Vladimir F. , Guzhova Irina V. , Margulis Boris A.
Published: May 2020

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a glycolytic enzyme whose role in cell metabolism and homeostasis is well defined, while its function in pathologic processes needs further elucidation. Depending on the cell context, GAPDH may bind a number of physiologically important proteins, control their function and correspondingly affect the cell’s fate. These interprotein interactions and post-translational modifications of GAPDH mediate its cytotoxic or cytoprotective functions in the manner of a Janus-like molecule. In this review, we discuss the functional features of the enzyme in cellular physiology and its possible involvement in human pathologies. In the last part of the article, we describe drugs that can be employed to modulate this enzyme’s function in some pathologic states.
Morphological Responses and Gene Expression of Grain Amaranth (Amaranthus spp.) Growing under Cd
Authors: Lancíková Veronika , Tomka Marián , Žiarovská Jana , Gažo Ján , Hricová Andrea
Published: May 2020

Phytoremediation efficiency depends on the ability of plants to accumulate, translocate and resist high levels of metals without symptoms of toxicity. This study was conducted to evaluate the potential of grain amaranth for remediation of soils contaminated with Cd. Three grain amaranth varieties, “Pribina” (A. cruentus), “Zobor” (A. hypochondriacus x A. hybridus) and Plainsman (A. hypochondriacus x A. hybridus) were tested under different level of Cd (0, 5, 10 and 15 mg/L) in a hydroponic experimental treatment. All could be classified as Cd excluders or Cd-hypertolerant varieties able to grow and accumulate significant amounts of Cd from the hydroponic solution, preferentially in the roots. Under the highest level of Cd exposure, qRT-PCR expression analysis of five stress-related genes was examined in above- and below-ground biomass. The results show that the Cd concentration significantly increased the mRNA level of chitinase 5 (Chit 5) in amaranth roots as the primary site of metal stress. The involvement of phytochelatin synthase (PCS1) in Cd detoxification is suggested. Based on our findings, we can conclude that variety “Pribina” is the most Cd-tolerant among three tested and can be expected to be used in the phytomanagement of Cd loaded soils as an effective phytostabiliser.
Optimizing N Fertilization to Improve Yield, Technological and Nutritional Quality of Tomato Grown in High Fertility Soil Conditions
Authors: Ronga Domenico , Pentangelo Alfonso , Parisi Mario
Published: May 2020

Processing tomato is the second most important worldwide cash crop, generally produced in high-input systems. However, fruit yield and quality are affected by agronomic management, particularly nitrogen (N) fertilization, whose application to indeterminate growth genotypes for canning has yet to be investigated in depth. Hence, the objective of this work was to assess the effects of different N rates (0, 50, 125, 200, 275, and 350 kg ha−1) on fruit yield and quality characteristics of processing tomato ‘San Marzano’ landrace. The results of our study showed that 125 and 200 kg of N ha−1 are the most appropriate rates in soil with high fertility, ensuring the highest values of marketable yield and brix yield. However, plants fertilized with 125 kg of N ha−1 attained higher values of N efficiency and fruit K and P concentrations than plants fertilized with 200 kg of N ha−1. Our results suggest that overdoses of N supplies negatively affected fruit yield and quality of San Marzano landrace grown in high soil fertility conditions, also reducing the agricultural sustainability. Hence, specific agronomic protocol and extension services are required to optimally manage tomato crop systems.
Arabidopsis in the Wild—The Effect of Seasons on Seed Performance
Authors: de Souza Vidigal Deborah , He Hanzi , Hilhorst Henk W. M. , Willems Leo A. J. , Bentsink Leónie
Published: May 2020

Climate changes play a central role in the adaptive life histories of organisms all over the world. In higher plants, these changes may impact seed performance, both during seed development and after dispersal. To examine the plasticity of seed performance as a response to environmental fluctuations, eight genotypes known to be affected in seed dormancy and longevity were grown in the field in all seasons of two years. Soil and air temperature, day length, precipitation, and sun hours per day were monitored. We show that seed performance depends on the season. Seeds produced by plants grown in the summer, when the days began to shorten and the temperature started to decrease, were smaller with deeper dormancy and lower seed longevity compared to the other seasons when seeds were matured at higher temperature over longer days. The performance of seeds developed in the different seasons was compared to seeds produced in controlled conditions. This revealed that plants grown in a controlled environment produced larger seeds with lower dormancy than those grown in the field. All together the results show that the effect of the environment largely overrules the genetic effects, and especially, differences in seed dormancy caused by the different seasons were larger than the differences between the genotypes.
Cloning and Expression of a Perilla frutescens Cytochrome P450 Enzyme Catalyzing the Hydroxylation of Phenylpropenes
Authors: Baba Mariko , Yamada Ken-ichi , Ito Michiho
Published: May 2020

Phenylpropanoid volatile components in plants are useful and valuable not only as flavorings, but also as medicines and food supplements. The pharmacological actions and toxicities of these compounds have been well studied but their synthetic pathways are generally unclear. In this study, we mined expressed sequence tag libraries of pure strains of perilla maintained for over 30 years for their oil type and conducted gas chromatography-mass spectrometry analyses of the perilla oils to confirm the presence of monohydrates speculated to be intermediates of the phenylpropene synthetics pathways. These putative monohydrate intermediates and their regioisomers were synthesized to identify the reaction products of assays of heterologously expressed enzymes. An enzyme involved in the synthesis of a phenylpropanoid volatile component was identified in perilla. Expression of this enzyme in Saccharomyces cerevisiae showed that it is a member of the cytochrome P450 family and catalyzes the introduction of a hydroxy group onto myristicin to form an intermediate of dillapiole. The enzyme had high sequence similarity to a CYP71D family enzyme, high regiospecificity, and low substrate specificity. This study may aid the elucidation of generally unexploited biosynthetic pathways of phenylpropanoid volatile components.
Seed Germination after 30 Years Storage in Permafrost
Authors: Solberg Svein Øivind , Brodal Guro , von Bothmer Roland , Meen Eivind , Yndgaard Flemming , Andreasen Christian , Asdal Åsmund
Published: May 2020

More than 30 years ago, the Nordic Gene Bank established a long-term experiment on seeds stored under permafrost conditions in an abandoned mine corridor in Svalbard, as a tool to monitor storage life under these conditions. The study included seeds from 16 Nordic agricultural and horticultural crops, each represented by two or three cultivars (altogether 38 accessions). All seeds were ultra-dried to 3–5% moisture before being sealed in glass tubes. Germination tests were performed in accordance with the International Seed Testing Association (ISTA) protocols. At the initiation of the experiment, the samples showed good germination with the median value at 92%. The overall picture remained stable over the first twenty to twenty-five years. However, the variation became larger over time and at 30 years, the median value had dropped to 80%. At the lower end, with a high drop in germination, we found rye, wheat, and English ryegrass. At the upper end, we found Kentucky bluegrass and cucumber. The lowest germination was found in samples with the highest initial seed moisture levels. Pre-storage conditions are likely to be of major importance for longevity.
Ethylene is Involved in Symptom Development and Ribosomal Stress of Tomato Plants upon Citrus Exocortis Viroid Infection
Authors: Vázquez Prol Francisco , López-Gresa M. Pilar , Rodrigo Ismael , Bellés José María , Lisón Purificación
Published: May 2020

Citrus exocortis viroid (CEVd) is known to cause different symptoms in citrus trees, and its mechanism of infection has been studied in tomato as an experimental host, producing ribosomal stress on these plants. Some of the symptoms caused by CEVd in tomato plants resemble those produced by the phytohormone ethylene. The present study is focused on elucidating the relationship between CEVd infection and ethylene on disease development. To this purpose, the ethylene insensitive Never ripe (Nr) tomato mutants were infected with CEVd, and several aspects such as susceptibility to infection, defensive response, ethylene biosynthesis and ribosomal stress were studied. Phenotypic characterization revealed higher susceptibility to CEVd in these mutants, which correlated with higher expression levels of both defense and ethylene biosynthesis genes, as well as the ribosomal stress marker SlNAC082. In addition, Northern blotting revealed compromised ribosome biogenesis in all CEVd infected plants, particularly in Nr mutants. Our results indicate a higher ethylene biosynthesis in Nr mutants and suggest an important role of this phytohormone in disease development and ribosomal stress caused by viroid infection.
Response to Anthracnose in a Tarwi (Lupinus mutabilis) Collection Is Influenced by Anthocyanin Pigmentation
Authors: Guilengue Norberto , Neves-Martins João , Talhinhas Pedro
Published: May 2020

Anthracnose, caused by Colletotrichum lupini, is a major limiting factor for lupin production. Tarwi or Andean Lupin (Lupinus mutabilis) is generally regarded as susceptible to anthracnose, but the high protein and oil content of its seeds raise interest in promoting its cultivation in Europe. In this study we evaluated the response to anthracnose of 10 tarwi accessions contrasting in anthocyanin pigmentation, by comparison to white lupin (Lupinus albus), using a contemporary Portuguese fungal isolate. A severity rating scale was optimized, including weighted parameters considering the type of symptoms and organs affected. All tarwi accessions were classified as susceptible, exhibiting sporulating necroses on the main stem from seven days after inoculation. Anthracnose severity was lower on anthocyanin-rich tarwi plants, with accession LM34 standing out as the less susceptible. Accession I82 better combines anthracnose response and yield. In global terms, disease severity was lower on white lupin than on tarwi. Although based on a limited collection, the results of the study show the existence of genetic variability among L. mutabilis towards anthracnose response relatable with anthocyanin pigmentation, providing insights for more detailed and thorough characterization of tarwi resistance to anthracnose.
Genome-Wide Association Analysis Identifies Candidate Genes Regulating Seed Number per Silique in Arabidopsis thaliana
Authors: Jiang Huan-Li , Hong Jun , Jiang Yu-Tong , Yu Shi-Xia , Zhang Yan-Jie , Shi Jian-Xin , Lin Wen-Hui
Published: May 2020

Seed weight and number ultimately determine seed yield. Arabidopsis seed number comprised of silique number and seed number per silique (SNS). Comparing seed development and weight, determinants of seed number remain largely uncharacterized. In this study, taking advantage of 107 available Arabidopsis accessions, genome-wide association analysis (GWAS) was employed to identify the candidate genes regulating SNS. GWAS-based genotype and phenotype association analysis identified 38 most significant SNPs marker sites that were mapped to specific chromosomal positions and allowed us to screen for dozens of candidate genes. One of them (PIN3) was selected for functional validation based on gene expression analysis. It is a positive regulator of Arabidopsis SNS. Although silique length of PIN3 loss of function mutant was not significantly changed, its SNS and seed density (SD) were significantly reduced as compared with the wild type. Notably, PIN3 overexpression lines driven by a placenta-specific promoter STK exhibited significantly shorter siliques, slightly reduced SNS, but significant increased SD compared with wild type, suggesting that PIN3 positively regulates SD through inducing ovule primordia initiation regardless of the placenta size. Ovule initiation determines the maximal possibility of SNS, and new genes and mechanism regulating SNS through modulating ovule initiation is worth further investigated.
Insights into the SAM Synthetase Gene Family and Its Roles in Tomato Seedlings under Abiotic Stresses and Hormone Treatments
Authors: Heidari Parviz , Mazloomi Faezeeh , Nussbaumer Thomas , Barcaccia Gianni
Published: May 2020

S-Adenosyl-L-methionine (SAM) is a key enzyme involved in many important biological processes, such as ethylene and polyamine biosynthesis, transmethylation, and transsulfuration. Here, the SAM synthetase (SAMS) gene family was studied in ten different plants (Arabidopsis, tomato, eggplant, sunflower, Medicago truncatula, soybean, rice, barley, Triticum urartu and sorghum) with respect to its physical structure, physicochemical characteristics, and post-transcriptional and post-translational modifications. Additionally, the expression patterns of SAMS genes in tomato were analyzed based on a real-time quantitative PCR assay and an analysis of a public expression dataset. SAMS genes of monocots were more conserved according to the results of a phylogenetic analysis and the prediction of phosphorylation and glycosylation patterns. SAMS genes showed differential expression in response to abiotic stresses and exogenous hormone treatments. Solyc01g101060 was especially expressed in fruit and root tissues, while Solyc09g008280 was expressed in leaves. Additionally, our results revealed that exogenous BR and ABA treatments strongly reduced the expression of tomato SAMS genes. Our research provides new insights and clues about the role of SAMS genes. In particular, these results can inform future functional analyses aimed at revealing the molecular mechanisms underlying the functions of SAMS genes in plants.
Development of a Highly Proliferated Bilayer Coating on 316L Stainless Steel Implants
Authors: Khosravi Fatemeh , Nouri Khorasani Saied , Khalili Shahla , Esmaeely Neisiany Rasoul , Rezvani Ghomi Erfan , Ejeian Fatemeh , Das Oisik , Nasr-Esfahani Mohammad Hossein
Published: May 2020

In this research, a bilayer coating has been applied on the surface of 316 L stainless steel (316LSS) to provide highly proliferated metallic implants for bone regeneration. The first layer was prepared using electrophoretic deposition of graphene oxide (GO), while the top layer was coated utilizing electrospinning of poly (ε-caprolactone) (PCL)/gelatin (Ge)/forsterite solutions. The morphology, porosity, wettability, biodegradability, bioactivity, cell attachment and cell viability of the prepared coatings were evaluated. The Field Emission Scanning Electron Microscopy (FESEM) results revealed the formation of uniform, continuous, and bead-free nanofibers. The Energy Dispersive X-ray (EDS) results confirmed well-distributed forsterite nanoparticles in the structure of the top coating. The porosity of the electrospun nanofibers was found to be above 70%. The water contact angle measurements indicated an improvement in the wettability of the coating by increasing the amount of nanoparticles. Furthermore, the electrospun nanofibers containing 1 and 3 wt.% of forsterite nanoparticles showed significant bioactivity after soaking in the simulated body fluid (SBF) solution for 21 days. In addition, to investigate the in vitro analysis, the MG-63 cells were cultured on the PCL/Ge/forsterite and GO-PCL/Ge/forsterite coatings. The results confirmed an excellent cell adhesion along with considerable cell growth and proliferation. It should be also noted that the existence of the forsterite nanoparticles and the GO layer substantially enhanced the cell proliferation of the coatings.
Synthesis and Characterization of Hollow-Sphered Poly(N-methyaniline) for Enhanced Electrical Conductivity Based on the Anionic Surfactant Templates and Doping
Authors: Direksilp Chatrawee , Sirivat Anuvat
Published: May 2020

Poly(N-methylaniline) (PNMA) is a polyaniline derivative with a methyl substituent on the nitrogen atom. PNMA is of interest owing to its higher solubility in organic solvents when compared to the unsubstituted polyaniline. However, the electrical conductivity of polyaniline derivatives suffers from chemical substitution. PNMA was synthesized via emulsion polymerization using three different anionic surfactants, namely sodium dodecylsulfate (SDS), sodium dodecylbenzenesulfonate (SDBS), and dioctyl sodium sulfosuccinate (AOT). The effects of surfactant structures and concentrations on electrical conductivity, doping level, crystallinity, morphology, and thermal stability were investigated. The re-doping step using perchloric acid (HClO4) as a dopant was sequentially proceeded to enhance electrical conductivity. PNMA synthesized in SDBS at five times its critical micelle concentration (CMC) demonstrated the highest electrical conductivity, doping level, and thermal stability among all surfactants at identical concentrations. Scanning electron microscopy (SEM) images revealed that the PNMA particle shapes and sizes critically depended on the surfactant types and concentrations, and the doping mole ratios in the re-doping step. The highest electrical conductivity of 109.84 ± 20.44 S cm−1 and a doping level of 52.45% were attained at the doping mole ratio of 50:1.
Influence of Oxidation Degree on the Physicochemical Properties of Oxidized Inulin
Authors: Afinjuomo Franklin , Fouladian Paris , Barclay Thomas G. , Song Yunmei , Petrovsky Nikolai , Garg Sanjay
Published: May 2020

This paper reports the oxidation of inulin using varying ratios of sodium periodate and the characterization of the inulin polyaldehyde. The physicochemical properties of the inulin polyaldehyde (oxidized inulin) were characterized using different techniques including 1D NMR spectroscopy, 13C Nuclear magnetic resonance (NMR), Fourier transform infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA), differential scanning calorimetric (DSC), ultraviolet-visible spectroscopy (UV), and scanning electron microscopy (SEM). The aldehyde peak was not very visible in the FTIR, because the aldehyde functional group exists in a masked form (hemiacetal). The thermal stability of the oxidized inulin decreased with the increasing oxidation degree. The smooth spherical shape of raw inulin was destructed due to the oxidation, as confirmed by the SEM result. The 1HNMR results show some new peaks from 4.8 to 5.0 as well as around 5.63 ppm. However, no aldehyde peak was found around 9.7 ppm. This can be attributed to the hemiacetal. The reaction of oxidized inulin with tert-butyl carbazate produced a carbazone conjugate. There was clear evidence of decreased peak intensity for the proton belonging to the hemiacetal group. This clearly shows that not all of the hemiacetal group can be reverted by carbazate. In conclusion, this work provides vital information as regards changes in the physicochemical properties of the oxidized inulin, which has direct implications when considering the further utilization of this biomaterial.
Effect of Gelatin Coating Enriched with Antioxidant Tomato By-Products on the Quality of Pork Meat
Authors: Gallego Marta , Arnal Milagros , Talens Pau , Toldrá Fidel , Mora Leticia
Published: May 2020

The use of edible biopolymers and natural additives obtained from food processing by-products is a sustainable strategy for food packaging applications. Gelatin is a biopolymer with great potential as a coating due to its low cost, high availability, and technological and functional properties. Among them, gelatin can be used as a carrier of bioactive compounds such as antioxidants, which can retard oxidation processes and thus extend the shelf-life of highly-perishable products. This study evaluated the effect of gelatin coating enriched with antioxidant tomato by-products hydrolysate (TBPH) on the quality of pork meat during cold storage. Results showed that TBPH obtained from Alcalase hydrolysis presented antioxidant activity with good stability against cooking. Additionally, chromatographic and mass spectrometry techniques, as well as in silico analysis, were used for the peptidomic characterisation of TBPH. The application of enriched gelatin coating on meat led to some physicochemical changes including increased weight loss and colour differences; however, the pH and water activity, which control meat spoilage, were maintained during storage. Moreover, coating prevented lipid oxidation of meat, and enriched-coated meat presented high antioxidant activity after cooking. These results suggest the positive role of gelatin coating enriched with TBPH in extending the shelf-life of meat during storage.
Consolidation of Fir Wood by Poly(vinyl butyral-co-vinyl alcohol-co-vinyl acetate) Treatment: Study of Surface and Mechanical Characteristics
Authors: Harandi Danial , González-Benito Javier , Olmos Dania
Published: May 2020

The ability of poly(vinyl butyral-co-vinyl alcohol-co-vinyl acetate) (PVBVA) to consolidate Fir wood was studied in terms of the surface and mechanical properties’ changes. Two variables were considered to treat the wood: (i) the concentration (5 and 10 wt.%) of PVBVA solutions and (ii) the method of application (brushing and immersion). The presence of PVBVA on the wood surfaces was confirmed by infrared spectroscopy. Surface roughness measured by optical profilometry did not reveal changes in the topography of the samples, and appropriate visual appearance was confirmed. Contact angle measurements showed that a droplet of the 10%-PVBVA solution needed ~50 s to reach the same contact angle decreasing rate as that measured for the 5%-PVBVA solution, suggesting there was some kind of induction time till the spreading process was no longer controlled by the viscosity, but by the solution-wood interactions. Water contact angle (WCA) measurements proved a more hydrophobic surface of the PVBVA-treated samples, compared to untreated wood. Mechanical characterization of the samples was done macroscopically by a three-point bending test and locally by the Shore D and Martens hardness (MH). Only results from MH experiments provided comparative results, indicating that treatment with PVBVA solutions increased wood hardness locally, being enhanced with solution concentration. The best surface mechanical properties were obtained for the samples immersed in the 10%-PVBVA solution.
Simulations and dSPACE Real-Time Implementation of Photovoltaic Global Maximum Power Extraction under Partial Shading
Authors: A. Alturki Fahd , Al-Shamma’a Abdullrahman A. , M. H. Farh Hassan
Published: May 2020

Under partial shading conditions (PSCs), solar photovoltaic (PV) energy systems generate multiple peaks; one global peak (GP) and several local peaks (LPs). Thus, tracking the GP of the PV systems under PSCs is necessary to enhance the system reliability and efficiency. Conventional maximum power point tracker (MPPT) algorithms are capable of tracking the unique peak under uniform conditions but they fail to track the GP under PSCs. To the best of our knowledge, this paper represents the first study that introduces a comprehensive comparison of three efficient maximum power point tracker (MPPT) algorithms that are used to extract the GP of the PV system under both uniform and PSCs. These MPPT techniques include two metaheuristic techniques, which are cuckoo search optimization (CSO) and particle swarm optimization (PSO) techniques in addition to one conventional MPPT; perturb and observe (P&O). Although the simulation and dSPACE-based experimental results demonstrated the superiority of CSO and PSO in tracking the GP, CSO requires less tracking time and thus provides a higher efficiency than the PSO. In addition, P&O can be used to follow the first peak, regardless if it is a local peak or global peak with notable oscillation.
Food Insecurity in Advanced Capitalist Nations: A Review
Authors: Long Michael A. , Gonçalves Lara , Stretesky Paul B. , Defeyter Margaret Anne
Published: May 2020

Food insecurity is a substantial problem in nearly every advanced capitalist nation, with sizable portions of residents in many affluent countries struggling to eat healthily every day. Over time, a very large literature has developed that documents food insecurity, evaluates programs meant to reduce that insecurity, and proposes solutions to attenuate the problem. The purpose of the current review is to provide a very broad overview of the food insecurity literature, including definitions, measurement, areas of study, and impacts on health. Importantly, this review suggests there are two major causes of food insecurity in the advanced nations: economic inequality and neoliberalism. The food insecurity literature suggests that diminished government responsibility in advanced capitalist nations corresponds to an increase in feeding programs run by non-profit and charitable organizations. This review concludes by suggesting that, while a massive amount of research on food insecurity currently exists, more research is still needed to address gaps in the literature when it comes to significant events, coping strategies and disadvantaged populations.
Methodology for Gender Analysis in Transport: Factors with Influence in Women’s Inclusion as Professionals and Users of Transport Infrastructures
Authors: García-Jiménez Elena , Poveda-Reyes Sara , Molero Gemma Dolores , Santarremigia Francisco Enrique , Gorrini Andrea , Hail Yvonne , Ababio-Donkor Augustus , Leva Maria Chiara , Mauriello Filomena
Published: May 2020

This work analyzes gendered processes by a methodology based on clustering factors with influence in the decision-making process of women as users or employees of the transport system. Considering gender as a social construction which changes over time and space, this study is based on the concept of a woman as a person who adopts this role in society. This paper performs a deep analysis of those factors women consider as needs and barriers to use or work in the transport system in four scenarios: railway public transport infrastructures, automated vehicles, bicycle sharing, and jobholders. A literature review and focus group discussions were performed under the consideration that the definition of woman includes the addition of several personal characteristics (age, sexual orientation, family responsibilities, and culture). The data analysis allowed the identification of fairness characteristics (FCs) that affect the interaction of women with the transport system for each scenario. A methodology for clustering the fairness characteristics identified the main areas of action to improve the inclusion of women within each use case. Further studies will be focused on the quantification and prioritization of the FCs through mathematical methods and the suggestion of inclusive measures by an interdisciplinary panel.
Digital Twin of Experimental Smart Manufacturing Assembly System for Industry 4.0 Concept
Authors: Židek Kamil , Piteľ Ján , Adámek Milan , Lazorík Peter , Hošovský Alexander
Published: May 2020

This article deals with the creation of a digital twin for an experimental assembly system based on a belt conveyor system and an automatized line for quality production check. The point of interest is a Bowden holder assembly from a 3D printer, which consists of a stepper motor, plastic components, and some fastener parts. The assembly was positioned in a fixture with ultra high frequency (UHF) tags and internet of things (IoT) devices for identification of status and position. The main task was parts identification and inspection, with the synchronization of all data to a digital twin model. The inspection system consisted of an industrial vision system for dimension, part presence, and errors check before and after assembly operation. A digital twin is realized as a 3D model, created in CAD design software (CDS) and imported to a Tecnomatix platform to simulate all processes. Data from the assembly system were collected by a programmable logic controller (PLC) system and were synchronized by an open platform communications (OPC) server to a digital twin model and a cloud platform (CP). Digital twins can visualize the real status of a manufacturing system as 3D simulation with real time actualization. Cloud platforms are used for data mining and knowledge representation in timeline graphs, with some alarms and automatized protocol generation. Virtual digital twins can be used for online optimization of an assembly process without the necessity to stop that is involved in a production line.
Effects of Different Weeding Methods on the Biomass of Vegetation and Soil Evaporation in Eucalyptus Plantations
Authors: Deng Yusong , Yang Gairen , Xie Zhifeng , Yu Jingrui , Jiang Daihua , Huang Zhigang
Published: May 2020

Eucalyptus is a fast-growing, short-cycle, and high-efficiency tree species that is widely planted all over the world. Weeding is a special practice for Eucalyptus plantations that aims to cultivate seedlings and reduce vegetation competition for nutrients. In this study, a typical Eucalyptus plantation was selected as the research object, and the effects of two different weeding methods on soil evaporation and plant growth were studied. The results showed that mechanical weeding could effectively remove harmful weeds at an early stage, but after 30 days of weeding, all kinds of plants gradually recovered; herbicide weeding required long-term maintenance. The herbicide had the best control effect on Microstegium vagans (Nees ex Steud.) A. Camus, Dicranopteris dichotoma (Thunb.) Bernh, and Blechnum orientale, but the effect on shrubs was not obvious. The evaporation rate of soil increased rapidly within five days after mechanical weeding. After 139–200 days of weeding, the differences in evaporation between non-weeding, herbicide weeding, and mechanical weeding was decreased. The average daily evaporation was 0.52, 0.48, and 051 mm/d under these three practices. Meanwhile, weeding could promote Eucalyptus growth. Our results showed that weeding could significantly increase the height, diameter at breast height, and volume of Eucalyptus. One month after herbicide weeding or mechanical weeding (July), the height, DBH, and volume of Eucalyptus were significantly greater than those under non-weeding, but there was no significant difference between herbicide weeding and mechanical weeding. In addition, according to the different initial moisture contents, the evaporation rate increased with increasing initial moisture content and showed a very significant correlation.
Comparison of the Spatiotemporal Dynamics of Land Use Changes in Four Municipalities of China Based on Intensity Analysis
Authors: Tong Siqin , Bao Gang , Rong Ah , Huang Xiaojun , Bao Yongbin , Bao Yuhai
Published: May 2020

Land use/cover change (LUCC) is becoming one of the most important and interesting problems in the study of global environmental change. Identifying the spatiotemporal behavior and associated driving forces behind changes in land use is crucial for the regional sustainable utilization of land resources. In this study, we consider the four municipalities of China (Beijing, Tianjin, Shanghai, and Chongqing) and compare their spatiotemporal changes in land use from 1990 to 2015 by employing intensity analysis and barycenter migration models. We then discuss their driving forces. The results show that the largest reduction and increase variations were mainly concentrated in arable and construction land, respectively. The decrement and increment were the largest in Shanghai, followed by Beijing and Tianjin, and the least in Chongqing. Furthermore, the results of the barycenter migration model indicate that in addition to Beijing, the migration distances of construction land were longer than those of arable land in three other cities. Moreover, the application of intensity analysis revealed that the rate of land use change was also the greatest in Shanghai and the slowest in Chongqing during the whole study period, with all of their arable land being mainly transformed into construction land. The driving force analysis results suggest that the spatial and temporal patterns of land use change were the results of the socio-economic development, national policies, and major events. In other words, where there was a high rate of economic and population growth, the intensity of land use change was relatively large.
Strategies of Managing Coach Driver Job Stress for Sustainable Coach Tourism Industry—The Use of DANP-V Model
Authors: Liu Chui-Hua
Published: May 2020

Coach drivers are integral to the coach tourism industry. However, they are susceptible to job stress in the tourism context. Few studies address this problem from a job stress theory and tourism scenario. This study, thus, examines the network relationships between criteria and proposes a physical and workable improvement plan. A novel DEMATEL-based ANP and VIKOR (DANP-V) model is used to examine the job stress criteria based on the transaction stress framework in the tourist coach context of Taiwan. The expert survey produced useful results. The influential network relation map (INRM) illustrates the sequence of improvement is job stressors, cognitive coping strategies, and stress outcomes. The gap values of the modified VIKOR suggest the first priority to reach the aspired level is reducing stress outcomes. However, teaching active action as a strategy to cope with job stress is a long-term goal. These results are formulated into an action plan and can be easily indexed and followed. The findings have practical implications for decision-makers and coach drivers and may contribute to coach driver job-related stress management, ultimately, helping the sustainability of coach tourism.
A Multi-Risk Methodology for the Assessment of Climate Change Impacts in Coastal Zones
Authors: Gallina Valentina , Torresan Silvia , Zabeo Alex , Critto Andrea , Glade Thomas , Marcomini Antonio
Published: May 2020

Climate change threatens coastal areas, posing significant risks to natural and human systems, including coastal erosion and inundation. This paper presents a multi-risk approach integrating multiple climate-related hazards and exposure and vulnerability factors across different spatial units and temporal scales. The multi-hazard assessment employs an influence matrix to analyze the relationships among hazards (sea-level rise, coastal erosion, and storm surge) and their disjoint probability. The multi-vulnerability considers the susceptibility of the exposed receptors (wetlands, beaches, and urban areas) to different hazards based on multiple indicators (dunes, shoreline evolution, and urbanization rate). The methodology was applied in the North Adriatic coast, producing a ranking of multi-hazard risks by means of GIS maps and statistics. The results highlight that the higher multi-hazard score (meaning presence of all investigated hazards) is near the coastline while multi-vulnerability is relatively high in the whole case study, especially for beaches, wetlands, protected areas, and river mouths. The overall multi-risk score presents a trend similar to multi-hazard and shows that beaches is the receptor most affected by multiple risks (60% of surface in the higher multi-risk classes). Risk statistics were developed for coastal municipalities and local stakeholders to support the setting of adaptation priorities and coastal zone management plans.
Developmental Sustainability through Heritage Preservation: Two Chinese Case Studies
Authors: Song Xiao , Cheong Kee-Cheok , Wang Qianyi , Li Yurui
Published: May 2020

Cultural heritage is a vital part of a society’s existence. This role has particular relevance for China, with arguably one of the largest stocks of cultural assets, tangible and intangible, in the world. Recognizing the tension between cultural preservation and economic development as a general context, this paper examines the specific additional challenges China faces in its rush towards economic development. In providing both generic and China-specific contexts, this paper has as its objective to understand how Chinese policy-makers, both central and local, attempt to resolve the contest between cultural preservation and economic development, specifically rural rejuvenation. Through two case studies—of Lijiang in Yunnan province and Rizhao in Shandong province—this paper shows contrasting strategies to leverage local intangible cultural assets. Comparing these strategies reveals both the advantages and challenges inherent in each. A successful strategy captures the benefits of cultural tourism while minimizing its costs.
High Plains Aquifer–State of Affairs of Irrigated Agriculture and Role of Irrigation in the Sustainability Paradigm
Authors: Ajaz Ali , Datta Sumon , Stoodley Scott
Published: May 2020

Groundwater depletion is a serious issue in the southern and central parts of the High Plains Aquifer (HPA), USA. A considerable imbalance exists between the recharge process and groundwater extractions in these areas, which threatens the long-term sustainability of the aquifer. Irrigated agriculture has a major share in the economy, and it requires high pumping rates in regions vulnerable to large groundwater level declines. A literature review has been conducted to understand the state of affairs of irrigated agriculture in the HPA, along with the dynamics of groundwater decline and recharge using statistical and remote-sensing based datasets. Also, three irrigation management and technology-based approaches have been discussed from the perspective of sustainability. The southern and central parts of the HPA consist mostly of non-renewable groundwater formations, and the natural water storage is prone to exhaustion. Moreover, the aforementioned regions have comparatively higher crop water requirement due to the climate, and irrigating crops in these regions puts stringent pressure on the aquifer. The upper threshold of irrigation application efficiency (IAE) is high in the HPA, and could reach up to 95%; however, considerable room for improvement in irrigation water management exists. In general, the practices of irrigation scheduling used in the HPA are conventional and a small proportion of growers use modern methods to decide about irrigation timing. Among numerous ways to promote sustainable groundwater use in the HPA, deficit irrigation, use of soil moisture sensors, and subsurface drip irrigation can be considered as potential ways to attain higher lifespans in susceptible parts of the aquifer.
Condition Monitoring of DC-Link Electrolytic Capacitors in PWM Power Converters Using OBL Method
Authors: Abo-Khalil Ahmed G. , Al-Qawasmi Abdel-Rahman , Eltamaly Ali M. , Yu B. G.
Published: May 2020

Since the lifespan of an electrolytic capacitor is relatively short compared to other power semiconductor devices, the failure rate accounts for 60% and, thus, it is the most vulnerable component of the power conversion device. Therefore, the accurate measurement of the lifetime of an electrolytic capacitor is very important in ensuring the reliability of the entire system, including the capacitor. In this paper, an online failure detection method for a DC-link electrolytic capacitor in a back-to-back Pulse width Modulation (PWM) converter using the opposition-based learning particle swarm optimization-based Support Vector Regression (OPSO-SVR) technique is proposed. In this method, the capacitance and the DC-link capacitor power have been used in offline mode for SVR training and testing. During the offline mode, the SVR parameters have been optimized with the OPSO algorithm to use online to estimate the real value of the DC-link capacitor. The experimental results prove the superiority of the proposed technique over the SVR.