bluuebunny/crossref_metadata_2025 huggingface dataset:
Alterations in viscera histoarchitecture and organosomatic index as biomarkers of toxicity induced by Aba-Eku and Olusosun solid waste landfill leachates in Rattus norvegicus
Authors: Alimba Chibuisi Gideon
Published: June 2024

Solid waste disposal generates leachate, a mixture of deleterious chemical, physical and microbial contaminants, which poses risk to human and wildlife health. Leachate toxicity on relative organ weight and histopathology of important viscera in mammalian body is scarce. Leachate induced toxic effects on organosomatic indices and histopathology of vital mammalian organs were investigated. Wister rats were orally exposed to 1 – 25 % of raw and simulated leachates from Aba-Eku and Olusosun landfills for 30 days. At post-exposure, organosomatic index and histoarchitectural assessment of major viscera (heart, spleen, thymus and lungs) were conducted. The physico-chemical and organic compositions of the leachates were analysed using standard protocol. The tested leachates decreased weekly and terminal body weights, and altered organosomatic index of examined viscera in rats. The histoarchitecture of the investigated viscera revealed pathologies that ranged from mild to severe degeneration, cellular infiltration, haemorrhage, congestion, necrosis, disorganization of tissues and vacuolations. Others include increased histiocytes within the bronchial associated lymphoid, lymphoid depletions, haemosiderin deposits and apoptosis were observed in the examined viscera. Physico-chemical analysis of the leachates showed different concentrations of toxic metals, PAHs and PCBs that were higher than national and international permissible limits allowed in wastewaters. The physico-chemical compositions of the leachates are capable of eliciting the observed alterations in organosomatic indices and histopathological lesions in mammalian viscera. Xenobiotic components of the leachates possibly generated free radicals and/or directly disrupted the organ architectures. These findings suggest health risk to wildlife and human population exposed to emissions from waste landfills.
Older adult victims of violence. Satisfaction with health services in primary care
Authors: Isalgué Marcillí Moraima , Pardo Fernández Alfredo , Isalgué Marsillí Yolaida , Isalgué Drullet Daniel , Ferrales Isalgué Rubisley
Published: June 2024

Introduction: the state of satisfaction of older adults with health services constitutes one of the determinants for healthy aging.  Objective: to characterize the state of satisfaction of older adults who are victims of violence with health services at the primary health care level Method: a descriptive study was carried out in clinic 23 of the Emilio Daudinot Bueno Polyclinic from December 2022 to May 2023. With a population of 307 older adults and the intentional sampling of 57 victims of violence. Primary data were obtained from documentary review, interviews and surveys and included percentage analysis for the variables age, sex, manifestations of violence, satisfaction with the care received at the medical office, members of the Basic Work Group and the polyclinic. Results: the age group 60-65 years predominated with 38.6 % and the female sex represented 61.4 %. 100% of those studied reported some of the manifestations of psychological violence. 50.9% of the older adults expressed being satisfied with the attention received in the doctor's office, 52.7% with the attention of the social worker and 54.4% with the services received in the physical medicine and rehabilitation room. Conclusions: the state of satisfaction of older adult victims of violence with health services at the primary health care level was characterized.
Clinical and epidemiological characterization of hospitalized patients with community-acquired pneumonia at the Hospital Escuela Eva Perón in the city of Granadero Baigorria, Argentina.Perón School Hospital of the city of Granadero Baigorria(Santa Fe, Argentina) years 2021-2023
Authors: Mathurin Esteban Pablo , Martínez Amezaga Dr. Luis Ignacio , Operto María Alejandra
Published: June 2024

Introduction: Community-acquired pneumonia (CAP) is a pathology of extensive prevalence in the population under study, with high morbimortality and high cost for the health system. Objectives: To describe the clinical and epidemiological characteristics of patients hospitalized for CAP at the Hospital Escuela Eva Perón in the city of Granadero Baigorria (Santa Fe, Argentina) during the period June 2021 to June 2023. Materials and methods: A quantitative, observational, descriptive, cross-sectional, retrospective study was carried out. A population of 91 male and female patients over 18 years of age admitted with a diagnosis of CAP in the medical clinic area of the Hospital Escuela Eva Perón was studied. The epicrises of the patients included in the study were observed and data from the history, physical examination and complementary studies were collected, which led to the creation of a data table for subsequent statistical analysis. Results: During the period studied, 91 patients were admitted with CAP, which constituted 5% of all admissions. The mean age was (52.0 ±16.9) years with a male frequency of 62%. The majority risk group according to the CURB-65 scale was group 2. Arterial hypertension (AHT) was an associated comorbidity in 38.5% of patients and the average number of days of hospitalization was (7 ± 5) days. The positivity of microbiological blood culture results was 18% at the expense of Streptococcus pneumoniae. Pleural effusion was present in 28% of patients. Conclusions: The frequency of admissions for CAP in the present study is considerable in relation to total admissions. More than one third of the patients admitted were hypertensive. Most cultures were negative and among the positive cultures the most frequent microorganism was Streptococcus pneumoniae
Pedagogical training in nursing, professional competencies and modes of action in community care
Authors: Ramos Vives Madelaime , Mena Lorenzo Juan Alberto , Ferro González Belkis
Published: June 2024

Nursing professionals require theoretical knowledge and practical skills to apply work alternatives in the community, in order to promote, maintain and restore the health of the population with community participation. Its training process is complex and multidimensional, manifesting its competence in the quality of professional performance, however, the pedagogical training process of nursing students currently presents insufficiencies in the development of professional competencies that contribute to the development of the mode of action to educate in the community. Objective: to argue the importance of professional competences and modes of action, deepening in the educating mode of action, as a fundamental element in the pedagogical training process of Bachelor of Nursing students in community care. Methods: the general dialectical-materialist method was used, making possible the use of theoretical and empirical methods. Likewise, a space is dedicated to the conceptual analysis and its characteristics. Results: the analysis of the object, the modes of action, the professional competences and the central character of the mode of action to educate in the Bachelor of Nursing student are systematized, based on the determination of its main tendencies. Conclusions: the importance of the pedagogical training of the Bachelor of Nursing student for his professional performance is recognized, taking into account the modes of action and professional competences demanded by society nowadays, mainly from the educating mode of action
Occupational Health and Safety in a Financial Company
Authors: Choque Ccanchi Corina Anabel , Quintana Dragichevich Christian Omar , Meneses Claudio Brian Andreé , Zapana Ruiz Jorge Arturo
Published: June 2024

Introduction: Concern for occupational safety and health has increased due to high rates of occupational accidents and diseases worldwide. In Mexico, Ecuador, Colombia, Bolivia and Chile, numerous cases of occupational accidents and diseases have been reported. Methods: The study was conducted using a qualitative and descriptive approach, employing interviews and case analysis. Six interviews were conducted with workers of a banking institution. Rigorous ethical criteria were applied and a four-stage analysis method was used. Results and Discussion: Despite training efforts and preventive measures, areas for improvement were identified in the banking company, such as the need to improve signage and attention to risk situations. Workers face health challenges, including muscle pain and work stress, which affect their performance. The company shows commitment to the safety and health of its employees, but the importance of individual responsibility and the need to comprehensively address the physical and mental health of employees is highlighted. Conclusions: The banking company demonstrates commitment to training and preventive measures, but greater attention to employee safety and health is required. Employees face ergonomic challenges and work stress, which highlights the importance of an occupational health and safety culture. It is essential to comprehensively address the physical and mental health of workers to ensure a safe and healthy work environment.
The nursing process for choriocarcinoma: main nursing diagnoses
Authors: Bueno Ribeiro Nathália Luíza , Maciel Rafael , Facina Brandão Patrícia , Alves dos Santos William
Published: June 2024

Introduction: Gestational trophoblastic neoplasia (GTN) encompasses a rare group of neoplasms characterized by the proliferation of trophoblastic tissue with progressive malignant potential. Included in this group of pathologies are: Complete Hydatidiform Spring (CHS), Partial Hydatidiform Spring (PHS), Invasive Spring (IM), Choriocarcinoma (CC) and Placental Site Trophoblastic Tumor (PTST). It is an invasive and malignant disease and is considered the most curable neoplasm of the human species when treated in a timely and appropriate manner, if identified correctly and early through blood tests such as β-HCG. Objectives: To propose the main nursing diagnoses for choriocarcinoma. Method: Cross-sectional, descriptive and prospective data analysis study. This method involved four stages: identifying the problem, searching the literature for primary studies and identifying the nursing diagnoses. The search used Health Sciences descriptors (DeCS): Nursing Diagnosis, Corioarcinoma, Obstetrics and in Portuguese. Results: 54 main nursing diagnoses for choriocarcinoma were described, including bleeding, nausea, acute pain, risk of infection, constipation, diarrhea and others. Conclusion: It can be concluded that choriocarcinoma is a serious complication during pregnancy and can lead to serious clinical complications for women if it is not treated early and accurately in order to control the disease. Through nursing diagnoses, interventions and outcomes, we can gain a better understanding of the disease and draw up an effective clinical approach.
The symbolic power of racist educational practices in rural contexts
Authors: Ruiz Facio Karina
Published: June 2024

The following essay argues about racist practices by observing them within an institution, whose objective is to propose effective pedagogical methodologies to contribute to the development and access to education in rural contexts. The text is interwoven and linked to the concept of power (symbolic), hence the precept of biopower arises. In order to understand this aspect, what for Foucault is genealogy is introduced within an institution, resulting in a transcendental ethical pedagogy, concludes that to eradicate these racist practices in rural contexts it is necessary to implement the transcendental method stipulated by Lonergan.
HUMAN IMMUNODEFICIENCY VIRUS HIV
Authors: Palomino U Brayan Alejandro
Published: June 2024

The HIV research project focused on deepening the understanding of the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS), as well as developing effective strategies for their prevention, diagnosis and treatment. Key aspects such as the epidemiology of HIV/AIDS, risk factors, prevention strategies and access to antiretroviral treatment were investigated. Literature review activities, analysis of epidemiological data, field studies and evaluation of public health interventions were carried out. Collaboration with research institutions, public health organizations and affected communities will be crucial, especially to include the perspectives of key populations such as people living with HIV and injecting drug users. The results are expected to contribute to scientific advancement, inform evidence-based health policies, and promote effective interventions to combat the HIV/AIDS epidemic.
Factors Limiting Entrepreneurship in Colombia
Authors: Vanegas Belis Nelson Jhackson
Published: June 2024

Through relevant literature review and analysis of various secondary data sources, several challenges faced by entrepreneurs in Colombia have been identified. One of the most significant challenges is lack of confidence in investment, resulting in reduced attraction of venture capital and limited availability of resources for the growth and expansion of startups. Additionally, regulatory complexity, corruption, and political instability negatively impact the business environment in the country. In Colombia, entrepreneurship encounters hurdles such as bureaucratic barriers, limited access to financing, and insufficient entrepreneurial training. However, there are also opportunities, including government initiatives in sectors like technology, culture, and agriculture. Streamlining administrative processes, improving access to financing, and strengthening entrepreneurial education are essential. Leveraging natural resources is also crucial. In summary, addressing these challenges and capitalizing on opportunities can drive the country’s economic and social development.
LIMITATIONS OF THE IMPLEMENTATION OF IFRS IN COLOMBIA, FOCUSED ON THE PYMES
Authors: Ochica Bernal Yuri Alejandra
Published: June 2024

In Colombia, with its lack of knowledge about international accounting standards and fear of starting with a new standard that will evolve the accounting of an entire country that is struggling every day to globalize, the implementation of International Financial Reporting Standards (IFRS) in Small and Medium-sized Enterprises (SMEs) presents a series of challenges and difficulties that can hinder its effective application. These difficulties include the lack of financial and human resources, the complexity of accounting standards, resistance to change on the part of entrepreneurs and accountants, as well as adaptation to a new regulatory and financial reporting framework. These obstacles can hinder the process of implementing IFRS in SMEs, requiring an additional effort from all involved parties such as entrepreneurs, professionals, and regulatory bodies.
The importance of implementing emotional intelligence in organizations
Authors: Morales Riaño Monica Paola
Published: June 2024

The objective of the research is to see the importance of emotional intelligence in work performance within organizations, focusing especially on the impact that different intelligences can have on the generation of knowledge in the work environment. The results obtained in this article demonstrate a strong correlation between emotional intelligence and job performance, indicating that as work becomes more complex, emotional intelligence becomes even more indispensable, and both cannot exist independently. of the other. Regarding the methodological approach, this study is based on a descriptive method, focused on the characterization and analysis of emotional intelligence and its influence in the workplace. A documentary design was used to collect data from various sources, such as books, or articles on the selected topic. The conclusions obtained provide significant reflections and contributions for future work in this field.
Postpartum nursing care for premature rupture of membranes
Authors: Aquino-Risco Nancy , Cabanillas-Chavez María Teresa , Morales-García Wilter C.
Published: June 2024

Introduction: Cesarean section is a surgical technique through an incision in the abdominal and uterine wall, before an unfeasible vaginal delivery or if there is maternal or fetal risk. The risk of bleeding in surgeries such as caesarean section does not allow early ambulation to begin, so it will be dependent on the care of the nurse. Objective: To recognize the role of nursing in the management of acute pain and uterine atony in a post-cesarean patient due to premature rupture of membranes in a National Hospital of Ayacucho, 2021. Methodology: Qualitative clinical case study, 29-year-old patient selected for convenience ; in which the Nursing Care Process (PAE) was applied as a methodology and the data collection instrument was the assessment sheet according to the eleven functional patterns of Marjory Gordon. Results: Nine nursing diagnoses have been identified, of which, through the AREA model, acute pain related to injury by physical agent has been prioritized: operative wound. Nursing interventions were carried out according to the NOC and NIC taxonomy, obtaining favorable results for the patient. Regarding the risk of complication, uterine atony, it is not yet possible to specify the results since the risk will continue in the coming days. Conclusions: The identification of the clinical aspects of the post-cesarean patient due to premature rupture of membranes was carried out, the interventions achieved favorable results in the patient. However, care is still continued due to the risk of uterine atony and, consequently, postpartum hemorrhage.
Nursing care in patients with severe preeclampsia
Authors: Espiritu-Gozar Nancy , Heredia-Garay Flor M. , Cabanillas-Chavez María Teresa , Morales-García Wilter C.
Published: June 2024

Introduction: Preeclampsia is a pregnancy and postpartum complication characterized by high blood pressure, being one of the most important public health problems; multisystem pathology of great variable severity, which may not present symptoms at the beginning; however, it can cause serious and even fatal complications for the mother and fetus.
Objectives: To know the nursing care in patients with severe preeclampsia.
Methodology: Qualitative study, with a single case design based on the nursing care process method, applying the functional pattern assessment guide according to Marjorie Gordon to a 34-year-old primiparous pregnant woman with data from the clinical history, the interview, physical examination, and taxonomies (NANDA, NOC, NIC) that were used to formulate care plans.
Results: 9 nursing diagnoses with altered patterns were found, only one main diagnosis was prioritized: ineffective peripheral tissue perfusion r/c insufficient knowledge of the disease process with a problem associated with hypertension evidenced by edema, were the interventions performed satisfactory in the pregnant woman, before the CP gestational hypertension and the CR malignant hypertension, being the results defined by the time of intervention and evaluation.
Discussion: To conclude as specialist professionals we must make a good assessment and avoid any risk of complications in the pregnant woman. Due to the care provided in the gynecological emergency to the maternal-fetal binomial, a progressive evolution is observed with the preparation to be referred to the operating room.
Conclusions: Nursing care in clinical practice is very important when applying the nursing process that strengthens the autonomy of nursing in patients with severe preeclampsia, since the professional specialist in obstetrics and gynecology provides quality standards.
The Organizational Culture as a Driver of Business Growth: A Comprehensive Approach
Authors: Losada Madersson Fabian
Published: June 2024

The research article examines the influence of organizational culture on business growth through three interconnected dimensions: elements of organizational culture, internal culture, and external culture. It highlights that organizational culture, composed of shared values, beliefs, norms, and behaviors, defines a company's identity and affects its ability to innovate, adapt, and compete in the global market. It analyzes how organizational culture influences strategic decision-making, human resource management, and external relations. The conclusion drawn is that a solid and well-managed organizational culture is a key differentiator that drives performance, productivity, and adaptability in a company, significantly contributing to its continued growth and success in a dynamic and competitive business environment
Citizen Participation in Development Planning: Exploring its Impact and Challenges in Colombia
Authors: Valderrama Patiño Eduvier
Published: June 2024

The research article addresses the importance of citizen participation in the design, execution, and success of development plans in Colombia. It emphasizes that the voice and action of citizens are fundamental to the legitimacy of public policies and the very essence of democracy. The research focuses on examining how citizen participation influences the effectiveness, legitimacy, and relevance of government policies, with the aim of understanding how this interaction shapes the course of contemporary societies.
A methodology based on literature review and critical analysis of existing literature on citizen participation and development plans is developed. Three crucial aspects are identified: the historical and conceptual evolution of citizen participation, the forms of citizen participation and their impact on decision-making, and emblematic cases of citizen participation in development globally. The conclusions highlight the gradual evolution of citizen participation in Colombia and the need to address persistent challenges such as the digital divide and representativeness. The importance of promoting civic education, improving transparency and accountability, and strengthening communities' capacity to participate effectively in decision-making processes is emphasized
How are we to interpret this then? Social cartography, transdiscipline and epistemological disorder working with three social health organizations to the south of Buenos Aires
Authors: Gelman Constantin Francisco , Sy Anahí , Derossi Paula , Moglia Brenda , Sapienza Cinthia
Published: June 2024

The presentation dealt with an experience of a transdisciplinary research project carried out with different spaces of participation and territorial work, close to the National University of Lanús. Methodologically, it put into practice collectively social mapping. The selected spaces - an community orchard, a soup kitchen and a day center for the elderly - were linked in different ways to health care in an integral sense. The objective was to understand the way in which care strategies and practices were deployed in these spaces before, during and after the COVID-19 pandemic. Each of the three experiences had its particularities, but as a whole they represented an instance of dislocation of the place of disciplinary knowledge in the production and interpretation of the cartographic object. Cartography is linked to colonial expansion, its maps function as a mode of appropriation of the real; social cartography, on the other hand, proposes a counter-geography, subverting the established order through a reconfiguration of territories.(1) In this sense, knowledge was deployed through novel ways of writing and reading. Likewise, the feedback spaces contributed to the reworking with the organizations, outside the conventional epistemic and analytical parameters. When it came to interpretation, mapping also disarmed and reconfigured the researchers for the analysis, favoring an inter, multi- and transdisciplinary dialogue that operated on images, memories and accounts of experience towards the production of a knowledge in movement
History as an instrument of empowerment, the case of CORESA
Authors: Marelli Silvia Elizabeth
Published: June 2024

To understand where we are today, it is necessary to review the past" this phrase has been the starting point of the workshops that have been given with the purpose of providing theoretical tools (social exclusion, urban marginality and environmental degradation) to the Informal recyclers comrades who are part of the pre-cooperative CORESA (Community of Recoverers of Santiago del Estero). The main premise to incorporate the workshop called "History of the Carton Movement" in the training cycle has been to discuss and reflect among all members of CORESA the historical events that have delineated the emergence of public policies that favor the movement, such as the one implemented in recent years around the Inclusive Integrated Management of Solid Urban Waste
Role of political ideology in information monitoring and opinion change
Authors: Nogueroles Patricio , Alves Salgueiro Tomás , Vera Stefan Efraín , Muñoz Valderrama Carlos Luddwing , Fernández Larrosa Pablo Nicolás
Published: June 2024

Political Ideology (PI) is a system of representations that can serve as an anchor at the cognitive (individual) level to evaluate relevant information in Complex Decision Making (CDM (1)), but also as a political (social) map on which to identify options (2). This can be understood as a cognitive shortcut (heuristic) of information to make decisions with minimum cognitive effort (3) (more automatically).Two online experiments were conducted through the Neuron.AR platform during the Argentinean elections (general and ballotage) of 2023 to evaluate how PI modulates the valuation of semantic content and induces a change of opinion. In both, personal information (age, gender, residence, social status, etc) of the subjects was recorded. The political and ideological orientation of the participants was characterized through their self-perception, and operationally on a scale of progressivism and conservatism (based on the response to conservative or progressive items (4)), the closeness to the candidates and the political (symbolic) perception of candidates. Then, the change in the valuation of the items of the conservatism or progressivism scale was evaluated, but this time associated with a right-wing or left-wing candidate.The first experiment was carried out by 2839 people and the second by 1294. The symbolic and operational PI scales correlated consistently. From left to right, the candidates were ranked in the following order: Bregman, Massa, Schiaretti, Bullrich and Milei. Participants who identified more to the left or to the right showed greater change in ratings of both conservative and progressive items, regardless of whether these items were associated with a right- or left-wing candidate. The results support the hypothesis that ideology may function as a heuristic anchor, rather than a social map, in the process of monitoring information relevant to BDT
Generation of interdisciplinary and transdisciplinary knowledge in foresight through the scenario method
Authors: Patrouilleau María Mercedes
Published: June 2024

There is an area of multidisciplinary research for which inter- and transdisciplinary production is fundamental. This is foresight or futures studies. This discipline, which deals with inquiring about what may happen in the future to support present decisions, is based on the production of interdisciplinary and transdisciplinary knowledge, to know what the probable, possible and desirable futures of complex and ambiguous problems may be. To this end, a variety of methodologies taken from different scientific disciplines and areas of knowledge are used and adapted, and specific methods have also been designed to work on the future horizon, to denaturalize notions of temporality and to generate multicausal and alternative thinking. One of these is the narrative scenario method. This paper seeks to show some of the mechanisms used in the scenarios to generate inter- and transdisciplinary knowledge, the capacity of this method to integrate different methodological approaches and to show examples of the usefulness of this type of exercises to address complex problems, about which there is a wide uncertainty about their future development and different disputed values that are at stake in the issue. Specifically, it focuses on three mechanisms or methodological tools: 1. the special categories (prospective jargon), 2. the prospective funnel and 3. the images of the future and narratives. The main objective is to elucidate the role that inter- and transdisciplinary knowledge play in these elements. The examples given refer to exercises carried out in recent years in the field of agri-food and environmental foresight
Preimplantation Genetic Testing: Between the Private and the Public in the Era of Precision Medicine
Authors: Lima Natacha Salomé , Romero Miguel Adrián , Delvitto Ailin , Tropea Ana , Petino Zappala María Alejandra , Pallitto Nahuel , Pérez Ferretti Fernando , Paragis María Paula
Published: June 2024

This presentation is part of the Strategic Development Project PDE/6 2023-2024 funded by the Secretariat of Science and Technology of the University of Buenos Aires. The project aimed to produce a technical report addressing the scope and limitations of preimplantation genetic testing (PGT) in Argentina. The experiences, progress and findings of our interdisciplinary team comprising researchers from biological sciences and psychology are discussed here.Two fundamental aspects of the reproductive medicine field were addressed. Firstly, despite the existence of law 26,862/2013 covering assisted reproductive treatments, preimplantation genetic tests remain excluded from the Mandatory Medical Plan, highlighting access limitations. Moreover, challenges arise from the lack of specific regulations on central issues for the development of reproductive treatments, such as the legal status of non-implanted embryos. This particular situation prompted an analysis of the paradigm shift from collective health to precision medicine.Within this framework, our work critically examined the implications of PGT on approaches to knowledge and interventions in living organisms. We explored how PGT shapes notions of uncertainty, control, anticipation and the individualization of pathological conditions, shedding light on evolving forms of subjectivity. Additionally, we scrutinized genetic essentialism and determinism as discourses that either flatten differences or advocate for the "optimization" of life itself
The impact of frequently used herbicides in argentina, on cell lines
Authors: Sansalon Calén N. , Couto Facundo , Blaustein Matías , García Carrillo Mercedes
Published: June 2024

The use of herbicides worldwide is currently the subject of debate both within the scientific community and among the general public, focusing on their potential adverse effects onhuman health. However, there are few studies on the molecular and cellular changes produced by herbicides.(1-5)In this work, it was proposed to advance in the understanding of the cell signaling pathways affected by exposure to three herbicide formulations: RoundUp (RU, a.i.: glyphosate), Gesaprim (GS, a.i.: atrazine) and Paraquat Insuagro (PI, a.i.: paraquat). In particular, it was studied the effects of exposure to these formulations on the response to misfolded proteins or UPR, and the PI3K/Akt pathway in the HeLa Kyoto cell line. Dysregulation of these pathways has been reported to be associated with various malignancies.For all in vitro herbicide exposure assays, concentrations below the recommended application limit were chosen to evaluate the effect, on different exposure times on the regulation of both pathways.(6-14) For these purposes, western blot and fluorescence microscopy techniques were used.Results revealed activation of all three branches of the UPR (ATF6, PERK and IRE1) in those cells exposed to PI. On the other hand, ATF6 was activated as a result of GS exposure. In the case of RU, dysregulation of the PI3K/Akt pathway was observed, without detecting changes in the UPR. In conclusion, exposure of HeLa Kyoto cells to different herbicides leads to dysregulation of both the UPR and the PI3K/Akt pathway
Cooperation for the approach of popular libraries and Wikimedia in the management of cultural projects
Authors: Soler Juan , Bujan Gustavo , Rios Micaela Yanet , Yomha Cevasco Jazmín
Published: June 2024

Comprehensive Sexuality Education (CSE) constitutes a systematic space for teaching and learning about contents from different curricular areas, appropriate to the ages of boys and girls, and addressed in a cross-cutting manner and/or in specific spaces. From an integral conception, sexuality education includes the integration of physical, emotional, intellectual and social aspects related to sexuality. CSE is, at the same time, an opportunity for schools, in coordination with other actors, to offer effective responses to student rights violations -such as violence, abuse or mistreatment against children and adolescents- by undertaking protection and reparation measures. Previous studies recognize the importance of examining the Psychoeducation materials on Health Education topics, so it is necessary to investigate how learning can be facilitated from them. Considering the importance of examining this topic to promote students' health, we will first talk about the importance of CSE, then we will focus on previous literature to expose the main studies on strategies used by comprehenders at the time of learning (note taking - note review) and finally, we will comment on the importance of the modality of presentation of the material
Cooperation for the approach of popular libraries and Wikimedia in the management of cultural projects
Authors: Villarreal Mario
Published: June 2024

The presentation develops the experience of training popular libraries in Argentina that develop cultural management projects with a territorial and community perspective in cooperation with the National University of Villa María. The novelty of the proposal lies in the use of Wikimedia tools that have, among other aspects, the promotion of free and open culture and the decolonization of Internet content. Argentine popular libraries respond to their environment, providing their communities with cultural and educational assets that they would not otherwise be able to access. In this sense, the use of technological tools and free digital platforms such as Wikimedia can be of great help for the development of cultural projects that preserve and disseminate local heritage, promote cultural education and encourage reading. To achieve these objectives, it is essential to have adequate project management that allows planning, executing and evaluating the different actions developed within the framework of cultural projects. This implies moving from isolated activities to institutional projects that involve the community and the context. This is why the training proposal that we carry out has a strong axis in the recognition of cultural makers of our communities. The presentation will develop the assumptions that support the initiative as well as the educational strategy and finally reflections will be made on the impacts and scope of training. We hope to contribute to collective reflections that have at their center the right to culture and the decolonization of content on the internet
Conflicts over the use of agrochemicals in peri-urban areas: current regulations and perspectives in a district in the southeast of Buenos Aires
Authors: Zulaica Laura , Calderon Gabriela , Molpeceres Celeste , Gonzalez Insua Mariana
Published: June 2024

The peri-urban areas of Latin American cities register environmental problems linked to expansion processes. In the peri-urban area of Mar del Plata, General Pueyrredon District, the growth of the city translates into land use incompatibilities that have led to conflicts over the application of agrochemicals. This work traces the trajectory of the conflict while proposing to analyze the current regulations referring to the regulation of agrochemicals based on the development of thematic cartography. Based on official data, field surveys and interviews, maps were prepared using a Geographic Information System that allowed analyzing the potential and limitations of the implementation of the regulations. Current regulations show contradictions that limit their application. However, in the territory a paradigm shift in the way of production is gaining increasing strength that seeks to move towards more sustainable alternative models
Using mixed methods research: Contributions from a case working with people with Parkinson’s Disease
Authors: Bacigalupe María de los Angeles
Published: June 2024

Introduction: Mixed methods research has the potential to combine the use of quantitative and qualitative techniques and methods so that the greatest possible potential of fieldwork is achieved. The complexity of individual-environment relationships in situations that put health and life trajectories at stake is an appropriate context for applying the mixed approach. Here it presents its application in a work with people with Parkinson's Disease (PwPD). Methods: Intensive, situated, sequential mixed method approach with qualitative dominance, working with a non-parametric and convenience sample of PwPD in a local context. Results: It was observed that coping strategies did not show significant quantitative differences between two events determined a priori by the researcher based on the background (COVID-19 pandemic and diagnosis of Parkinson's Disease (PD)); However, qualitatively we found that the diagnosis constituted a clear turning point common to PwPD, unlike the pandemic. Conclusions: Although the initial intention was to work on the impact of the pandemic on the lives of PwPD (knowing from published background that the pandemic had affected people with chronic diseases whether or not they had suffered from coronavirus), the development of the study ledto resuming their life stories, emphasizing the particular issues linked to living with Parkinson's. Contrary to the assumptions, the determination of the coronavirus pandemic had not had the relevance as a turning point that the diagnosis of PD did represent.
Design of dengue and leptospirosis prevention strategies through participatory interventions in comparison with vertical strategies in riverside areas of Alto Verde (Santa Fe Capital): Preliminary results
Authors: Avalos Christian A. , Ricardo Tamara , Maglianese Mariana , Chiaraviglio Romina , Leiva Mariano , Bazán Rodriguez Ludmila , Beltramo Leda , Sanmartino Mariana , Mendicino Diego , Costa Federico , Previtali Andrea
Published: June 2024

This study focuses on the prevention of dengue and leptospirosis in vulnerable populations in the riverside area of the city of Santa Fe, Argentina, comparing the effectiveness of vector and reservoir control strategies through participatory interventions with a community approach, compared to traditional vertical strategies in riverside areas of Santa Fe. In the face of the hegemonic sanitary and medical model, it is necessary to provide more knowledge on the effectiveness of other possible forms of prevention, based on critical, socio-ecological, participatory models and approaches, which occur at the local scale, in the territories inhabited by the community. The methodology of the study comprised a quali-quantitative, randomized, controlled community trial with local community action. Two representative zones were selected from riverside sectors of Santa Fe, which share similar socioeconomic indices. In one area, participatory interventions were applied based on participatory action research, Citizen Science, and SEPA (Sociabilization of Evidence for Action) approaches. Simultaneously, and as a control, vertical and centralized prevention mechanisms were applied in the other zone.  In order to make comparisons of effectiveness, a characterization of the socio-environmental, sanitary, vector and reservoir conditions, and knowledge, attitudes and practices regarding these diseases was carried out in both zones, at pre- and post-intervention times.In exploratory analyses of the data collected, significant rates of change were found between both zones post-intervention, and a significant effect of the participatory interventions for response variables of health importance in dengue. Sampling for leptospirosis remains to be done
Bioinformatic analysis of the potential effects on human health of herbicides for alternative use to glyphosate and atrazine
Authors: Lorusso Tomas , Blaustein Matías , García Carrillo Mercedes
Published: June 2024

In Argentina, since the mid-90s, an agricultural model based on genetically modified crops and herbicides such as glyphosate and atrazine has been adopted [1]. The resistance of weeds to these herbicides has led to the use of alternatives such as glufosinate ammonium, alachlor and mesotrione, whose effects on human health are poorly studied [2]. This raises concerns, especially for possible carcinogenic effects, which underlines the need for more research on these alternative herbicides [3]. The objective of this study was to evaluate the potential toxicological effect of these alternative herbicides, identifying the proteins that can interact with them directly or indirectly using the STITCH and STRING platforms [4, 5]. Then, those biological processes potentially affected as a consequence of the interaction of these herbicides with the identified proteins were identified. An enrichment analysis was performed on those overrepresented proteins/genes associated with the category “Biological Process” and “KEGG PATHWAYS” from the Gene Ontology and SHINYGO databases respectively [6].It was found that, in general, these herbicides could affect both signaling pathways related to cell proliferation, programmed cell death, stress response, as well as the cellular response to xenobiotics, processing, maturation and biogenesis of ribosomal RNA. In addition, possible associated pathologies were found, such as neuro-degeneration, Lupus and cancer. These findings are consistent with previous reports on the toxic effects of these herbicides on human health, giving an account of their potential to produce diseases such as different types of cancer [7, 8, 9]
Peranan Pemerintah Islam dalam Sistem Negara Moden untuk Menerapkan Nilai Moral Islam: Daripada Penguat Kuasa ke Pemudah Cara
Authors:   International Institute of Advanced Islamic Studies (IAIS), Malaysia, Mansor Muhamad Sayuti
Published: June 2024

The implementation of Sharīʿah (taṭbīq al-Sharīʿah) by the Islamic government has been a longstanding principle in Islam, where the separation between state and religion, as observed in the West, is absent. However, the extent of the Islamic government’s involvement in enforcing moral standards in the modern state system remains a complex question. The advent of modernity, originating in the West, ushered in a bureaucratic concentration of state power, thereby transforming the process of implementation of morality, relegating them from the concerns of the state. The question thus has arisen whether Islam followed a similar trajectory. Therefore, this article aims to analyse the role of the Islamic government in the modern state era in implementing Islamic morality. This is achieved by unravelling the fundamental elements in the modern state system that have influenced the polemic on the legal enforcement of morality in the modern West, followed by a detailed comparative analysis with the jurisprudence of the Sharīʿah. This study reveals that as the primacy of morality prevails in Islamic law, the Islamic government in the modern state era continues to play a primary role in implementing and enforcing Islamic moral values. Notwithstanding, an approach that highlights a more appropriate role for the Islamic government as a facilitator in implementing Islamic morality, rather than merely as an enforcer, is very much needed.
Política de Comunicación Comunitaria en Bogotá: herramienta para el fortalecimiento de la ciudadanía y los procesos de participación. El caso de la organización Bogotá Social
Authors: Rodríguez Páez Luis Carlos , Aldana Orozco Yulieth
Published: June 2024

Este texto hace parte de la investigación titulada: “Política de Comunicación Comunitaria en Bogotá: herramienta para el fortalecimiento de la ciudadanía y los procesos de participación. El caso de la organización Bogotá Social, desarrollada en el marco de la Maestría en Paz, Desarrollo y Ciudadanía en la Corporación Universitaria Minuto de Dios -UNIMINUTO-. En efecto, busca exponer a través de un enfoque cualitativo el desarrollo y los hallazgos más representativos que tuvieron lugar durante el trámite de su objetivo, el cual estuvo orientado en comprender la manera en que incide la política pública distrital de comunicación comunitaria de Bogotá, en el ejercicio ciudadano del medio comunitario y alternativo Bogotá Social. Algunas de sus conclusiones más relevantes evidencian una política pública de comunicación comunitaria que incide en el ejercicio ciudadano del medio comunitario, por cuanto durante su construcción y consolidación es ella precisamente el motor de dos procesos interesantes de ciudadanía. Por un lado, se encuentra el ejercicio de una resistencia que pulula en el escenario de la macropolítica que, en segundo lugar, estimula al medio comunitario a la construcción de procesos asociativos de democracia participativa en esa misma escala.
WAYS TO IMPROVE TREATMENT EFFICACY IN OLDER ADULTS SUFFERING FROM NEUROPATHIC PAIN
Authors: Benlidayi Ilke Coskun
Published: June 2024

Neuropathic pain is frequently seen in older adults.  The treatment options include pharmacological and non-pharmacological strategies. Researchers have studied on the methods that can be used to improve therapy efcacy in older people who are suffering from neuropathic pain. These include, but are not limited to, accurate evaluation of positive and negative symptoms/signs, management of potential comorbidities or underlying diseases, mitigation of adverse events arising from therapeutic interventions, and personalized treatment. Clinical and biological markers are one of the most recent topics that have been proposed for personalized treatment. More studies are needed to improve our understanding on clinical and biological markers in the treatment of neuropathic pain. The current article aimed to review recent knowledge on the ways to improve treatment efcacy in older adults with neuropathic pain.
POLYCYSTIC OVARY SYNDROME: DIVERSE CLINICAL PRESENTATIONS ACROSS ADOLESCENCE, REPRODUCTIVE AGE, AND MENOPAUSE
Authors: Kabakchieva Plamena
Published: June 2024

Polycystic Ovary Syndrome (PCOS) is a multifaceted endocrine disorder affecting women across various life stages, presenting a wide array of symptoms that differ markedly during adolescence, reproductive age, and menopause. In adolescence, the overlap of PCOS symptoms with normal pubertal changes complicates diagnosis, with common presentations including menstrual irregularities, acne, and hirsutism. During the reproductive years, PCOS is often associated with infertility, menstrual dysfunction, and metabolic complications such as insulin resistance and type 2 diabetes. In menopausal women, reproductive symptoms diminish, but the risk of cardiovascular disease, persistent hyperandrogenism, and metabolic syndrome becomes more pronounced. This review aims to define the distinct clinical presentations of PCOS across these life stages, highlighting the diagnostic and management challenges inherent to its heterogeneous nature. By understanding the age-specific manifestations and complications of PCOS, healthcare providers can develop more effective, individualized therapeutic strategies, ultimately improving patient outcomes and quality of life.