bluuebunny/crossref_metadata_2025 huggingface dataset:
The Psychology Of Educational Aids And Their Impact On Teaching The Arabic Language To Non-Native Speakers/ سيكولوجية الوسائل التعليمية وأثرها في تعليم اللغة العربية للناطقين بغيرها
Authors: Abdullah Erfan Abdeldaym , Salem Alawadi Elsayed Mohamed , Bin Masman Haji Muhammad , Mahdi Rijal
Published: March 2024

This research emphasizes the overlooked importance of educational resources in Arabic language teaching for non-native speakers. It highlights the risks of choosing resources that do not align with students' preferences; the psychological impact of instructional materials on students' learning experiences is underscored by a call for building resources on psychological foundations for maximum effectiveness. The research employs a quantitative methodology. The survey, consisting of quantitative and qualitative questions, is administered to education practitioners and specialists. The study follows a descriptive method of data collection and analysis, emphasizing the quantitative aspects of the survey while also including qualitative insights from participants. Results have demonstrated the positive influence of educational materials on student performance. However, the psychological impact requires further investigation in teaching Arabic to non-native speaker.
Arabic Language Learning Methods In The Digital Era
Authors: Nafilah Sayidah Alfa , Hamidi Saddam Reza , Maulidiyah Robi'atul Laili , Faruq Muhammad , Mufidah Nuril
Published: March 2024

This study aims to describe the role of digital learning in Arabic and explain how effective methods are in learning Arabic in the digital era. This is qualitative descriptive research. Data was collected by observation and interviews with students of the 2023 Arabic language development special program at UIN Malang, Indonesia, about the learning methods used. The research results are that the currently developing digital era can make it easier for students to learn by using technology as a learning medium. A practical method of learning Arabic is getting used to answering online exercises to practice reading, writing, and speaking so that one can master learning Arabic. Apart from that, the current problem is that technology also hurts young people because of their dependence on cell phones, which can also be used as entertainment.
EMDR in Three Adults With Severe Intellectual Disability and Posttraumatic Stress Disorder: A Multiple-Baseline Evaluation
Authors: Hoogstad Annemieke , Mevissen Liesbeth , Didden Robert
Published: March 2024

Research on trauma treatment in people with severe intellectual disability (SID; IQ 20–35) is scarce, and controlled studies are lacking. This study examined the effectiveness of eye movement desensitization and reprocessing (EMDR) therapy using the storytelling method in three adults with SID and posttraumatic stress disorder (PTSD). A multiple-baseline design was used to examine the effects of EMDR storytelling method on PTSD classification, PTSD symptoms, challenging behaviors, and dysfunctional behaviors in three adults with SID and PTSD. EMDR resulted in a significant decrease in PTSD symptoms, challenging behaviors, and most dysfunctional behaviors. None of the participants had a PTSD classification anymore after EMDR. Findings suggest EMDR to be effective in the treatment of PTSD in adults with SID. Follow-up research with a larger sample size is required.
The Exosystem Impact: An Analysis of Male- and Female Physical Intimate Partner Violence Victimization in Heterosexual Relationships
Authors: Ballucci Dale , Ghebrai Sam , Haan Michael
Published: March 2024

An increasing body of sociological research explores the complexity of intimate partner violence (IPV) in heterosexual relationships. However, early research in this area concentrated exclusively on male perpetration, thereby necessitating a better understanding of the contexts behind female-perpetrated and bidirectional IPV. Using the two most recent cycles of the Canadian General Social Survey (2014 and 2019), our study employs a multinomial logistic regression model to examine the prevalence and severity of female and male physical IPV victimization among a large sample of married and common-law heterosexual couples. Framing our analysis through one concentric level of Dutton’s (1990) nested ecological model, the exosystem, we aim to understand whether these indicators serve as protective markers against severe and nonsevere physical IPV. We investigate the impact of eight exosystem indicators (financial stress, number of children, length of relationship, religiosity, employment, social support, education, and income). Our findings suggest that social support, employment, and household income serve as protective markers against male and female physical IPV victimization. Other protective factors include the length of the relationship and the partner’s religiosity for female-perpetrated violence. At the same time, the presence of children in the household reduces the likelihood of male-perpetrated IPV despite being a risk marker for female perpetration. Risk factors for both men and women include education and their partner’s employment. Future research should undertake a more in-depth exploration of the impact of exosystem and macrosystem factors on instances of IPV to generate a better understanding of predictive and preventative measures.
The Effect of Irrational Relationship Beliefs on Attitudes Toward Intimate Partner Violence in Emerging Adults: Moderating Effect of Gender
Authors: Yavuzer Yasemin , Kılıçarslan Suat
Published: March 2024

Attitudes toward intimate partner violence (IPVA) can be considered as approval/acceptance or disapproval/nonacceptance of physical violence against the intimate partner, psychological abuse, and control of the intimate partner. Individual (such as antisocial tendencies and irrational relationship beliefs [IRB]) and social factors (such as traditional norms and beliefs) shape IPVA. Studies on intimate partner violence (IPV) have revealed a significant relationship between IPVA and IPV. For this reason, IPVA is key to understanding IPV. This study was conducted to examine the effect of IRB on IPVA in Turkish emerging adults and the moderating effect of gender. Participants consisted of 551 students studying at a university in Central Anatolia. Of the participants, 374 were female, and the remaining 177 were male. All participants had at least one previous relationship experience. In the preliminary analysis performed, males’ IPVA scores were higher than those of females. The study findings revealed that IRB and gender positively and significantly predicted IPV attitudes. Another important finding showed that the effect of IRB on IPVA was stronger for females. The results highlighted the importance of working on transforming irrational beliefs into rational beliefs in women’s acceptance of IPV.
Efficacy, Complications and Effects of Alcides Pereira’s Sutures in the Management of Uterine Atony: A Retrospective Study
Authors: Cordeiro Féria Beatriz , Nazaré Patrícia , Figueiredo Joana , Neves Gomes Inês , Pereira Alcides
Published: March 2024

Introduction: Uterine compressive sutures are conservative measures applied in cases of severe postpartum hemorrhage unresponsive to uterotonics. Pereira’s suture was introduced in 2005 and consists of two longitudinal and three transverse non-transfixes sutures. Previous studies reported favorable results, highlighting its benefits and value. The aim of this study was to assess the efficacy, complications, and impact on fertility and future pregnancies of Pereira’s suture applied in cases of uterine atony and postpartum hemorrhage.Methods: An observational retrospective study was performed by consulting the medical records of women treated with Pereira’s compressive sutures in a tertiary center between January 2013 and December 2022. We registered demographic data, pregnancy outcomes, short-term complications, and outcomes of subsequent pregnancies.Results: A total of 50 women were treated with Pereira’s suture. The overall success rate was 96% and no hysterectomies were performed. Women who had sutures performed during an intra-cesarean section had better outcomes than those who had an after-cesarean section. Complications were reported in 12% (n = 6) of women, with the most frequent being pelvic infection (n = 3) and abdominal pain (n = 3). Regarding fertility, all women desiring a future pregnancy (n = 5) were able to conceive, resulting in three live births.Conclusion: Pereira’s suture is a type of suture that provides numerous advantages and should be considered when first-line medical treatment fails. When applied at an early stage, the sutures may prevent maternal morbidity. The Alcides Pereira’s suture is a safe technique and appears to preserve fertility.
Perspectiva de tempo futuro e a satisfação acadêmica
Authors: Nascimento Francielle Pereira , Oliveira Katya Luciane de , Bzuneck José Aloyseo
Published: March 2024

Introdução: Para a Perspectiva de Tempo Futuro, as metas futuras estipuladas pelos indivíduos têm efeito consciente e voluntário nos comportamentos do presente. Na universidade, estes comportamentos se manifestam paralelamente à satisfação ou insatisfação acadêmica. Objetivo: Sendo assim, o objetivo desta pesquisa foi analisar as relações entre a Perspectiva de Tempo Futuro e a satisfação com a experiência acadêmica. Metodologia: Participaram 676 universitários de diferentes cursos da graduação de duas instituições do Sul do Brasil. Aplicou-se o ZPTI – Inventário de Perspectiva de Tempo Futuro e o QSEA – Questionário de Satisfação com a Experiência Acadêmica. Resultados: Os resultados evidenciaram bons índices de estrutura interna para os instrumentos. A partir das análises descritivas e correlacionais, verificou-se que os estudantes orientados pelo presente-hedonista e presente-fatalista tendem a não ser orientados para o futuro. Já aqueles orientados pelo tempo futuro se sentem satisfeitos com sua própria aprendizagem e com seu rendimento acadêmico. Entretanto, estudantes orientados pelo passado negativo ou pelo presente fatalista são mais insatisfeitos com sua aprendizagem e seu rendimento. Conclusão: Diante dos resultados, verifica-se a necessidade das Instituições de ensino superior e seus docentes se apropriarem dos saberes relacionados aos universitários e aos componentes da vida acadêmica para que haja maior satisfação, bem como, perspectivas mais concisas de futuro.
Crystal structure prediction using neural network potential and age-fitness Pareto genetic algorithm
Authors: Omee Sadman Sadeed , Wei Lai , Hu Ming , Hu Jianjun
Published: March 2024

While crystal structure prediction (CSP) remains a longstanding challenge, we introduce ParetoCSP, a novel algorithm for CSP, which combines a multi-objective genetic algorithm (GA) with a neural network inter-atomic potential model to find energetically optimal crystal structures given chemical compositions. We enhance the updated multi-objective GA (NSGA-III) by incorporating the genotypic age as an independent optimization criterion and employ the M3GNet universal inter-atomic potential to guide the GA search. Compared to GN-OA, a state-of-the-art neural potential-based CSP algorithm, ParetoCSP demonstrated significantly better predictive capabilities, outperforming by a factor of $$ 2.562 $$ across $$ 55 $$ diverse benchmark structures, as evaluated by seven performance metrics. Trajectory analysis of the traversed structures of all algorithms shows that ParetoCSP generated more valid structures than other algorithms, which helped guide the GA to search more effectively for the optimal structures. Our implementation code is available at https://github.com/sadmanomee/ParetoCSP .
Firewalls, Hawking (Tolman) Radiation, and a Tentative Resolution of the Firewall-Mass Problem
Authors: Denur Jack
Published: March 2024

It has been theorized that black holes are surrounded by firewalls, although there is not universal agreement concerning this. We first review basic concepts pertaining to Schwarzschild black holes and Hawking radiation. Then we discuss the anticipation of Hawking radiation—albeit from non-black holes—initially by R. C. Tolman and shortly thereafter with P. Ehrenfest. We compare evaporation into a vacuum at absolute zero (0 K) of black holes with that of non-black holes, and show that not only black holes but also non-black holes evaporate within a finite time. The times required for evaporation of black holes and non-black holes are compared. Next, we show that (i) if firewalls exist, they can originate via Hawking radiation at the minimum possible ruler distance (the Planck length) beyond the Schwarzschild horizon, where it has not suffered any gravitational redshift, or, alternatively, suffered maximal gravitational blueshift and (ii) the firewall temperature is on the order of the Planck temperature, independently of the mass and hence also of the Schwarzschild radius of a Schwarzschild black hole. We then explain the exponential nature of the gravitational frequency shift as a function of the gravitational potential. Next, we consider the firewall-mass problem, and provide an at least prima facie tentative resolution thereto based on: (i) the mass of a firewall being canceled by the negative gravitational mass = (negative gravitational energy)/c2 accompanying its formation, (ii) the unchanged observations of a distant observer upon formation of a firewall, and (iii) Birkhoff's Theorem (actually first discovered by Jørg Tofte Jebsen). We then consider one aspect of thermodynamics in gravitational fields, showing that equilibrium relativistic gravitational temperature gradients cannot be exploited to violate the Second Law of Thermodynamics.
Fermentative utilization of glycerol by E. coli and its implications in biodiesel industry
Authors: Carvajal Ociel Cofre , Montes de Oca Jose Manuel Gomez , Moreno Domingo Cantero
Published: March 2024

The development of biofuels and biodiesel industry specifically, has resulted in the generation of large amounts of glycerol as a surplus. The conversion of glycerol, into chemicals with indus-trial interest, through anaerobic fermentation using E. coli as a biocatalyst is an attractive alter-native to improve economic performance in the biodiesel industry, for example through the bi-otransformation of residual glycerol into ethanol. For 2019, the size of the global ethanol market was valued at $ 89.1 billion US dollar. Biodiesel can be produced from several materials like rapeseed, palm, soya, corn, palm kernel, frying oil or olive-pomace oil (OPO). The last, can be extracted from alperujo, byproduct of olive oil process. However, olive-pomace oil converting into biodiesel is not enough established to achieve a global olive-oil/biodiesel derived process with minimized waste generation. Traditionally biodiesel production process produces an equivalent of 10% by mass of glycerol as a waste or by-product. This work explores the conver-sion of residual glycerol into chemicals like ethanol and hydrogen with a focus on projecting raw material potential availability from OPO, contributing to the promotion of the use of biofu-els and biodegradable compounds.
Measuring Device Detecting Impact Forces on Impact Rollers
Authors: Hrabovský Leopold , Kurač Daniel , Pravda Štěpán , Nováková Eliška , Machálek Tomáš
Published: March 2024

This paper presents laboratory devices on which experimental measurements were carried out to prove the validity of the assumption about the reduction of vibrations transmitted to the conveyor belt structure generated by the impact forces of falling material grains in the places of transfer or on the hoppers of conveyor belts. In order to limit damage to the conveyor belts caused by the impact of the sharp edges of material grains, conveyor belts are supported by impact rollers or impact rubber rods in the places of transfers and on the hoppers of belt conveyors. The flattened ends of the impact rollers are inserted into the grooves of steel brackets installed on the supports of the fixed conveyor idlers of a conventional design. In this paper, a special modification of the fixed conveyor idler is presented, which consists of inserting plastic brackets into the structurally modified roller axle holders of the fixed conveyor idler. Measurements were carried out on the first laboratory device, which showed that the specially modified fixed conveyor idler resulted in a higher damping of up to 15% of the impact forces of the falling weight on the rubberized hoop of the impact roller shell compared to the conventional fixed conveyor idler design. Measurements carried out on the second laboratory device show that the effective vibration velocity values detected at the points where the impact roller axis fits into the fixed roller table holder, i.e. points B and D, are higher than when using plastic brackets, up to 6% for a 108 mm diameter roller, compared to steel impact roller brackets.
Gene-Edited Medicinal ‘Superplants’: Advancements for Prolonged Space Travel
Authors: Nair Shreya
Published: March 2024

Space exploration is an arduous journey, with future explorations extending in duration, increasing the risk for common space-related health issues such as bone density loss due to microgravity, impaired gut microbiota, cardiovascular ailments, and exposure to cosmic radiation. These ailments can be addressed using medicinal plants. Enhancing their efficacy entails employing gene editing to target specific secondary metabolite pathways associated with therapeutic properties. Moreover, gene editing can combine multiple medicinal properties from various plants, culminating in a singular 'superplant' with enhanced therapeutic benefits. This review discusses the current usage of medicinal plants in promoting human health during space travel, the application of gene editing technology in modifying medicinal plants and presents a vision for the utilization of gene-edited medicinal plants in space to mitigate the risk of various space-related health issues.
Composition of Whole Grains Dietary Fibres and Phenolic; and Its Impact on Markers of Inflammation; Role of Gut Microbiota
Authors: Khan Jabir , Gul Palwasha , Rashid Muhammad Tayyab , Li Qingyun , Liu Kunlun
Published: March 2024

Inflammation is an important biological response to any tissue injury. The immune system responds to any stimulus, such as irritation, damage, or infection, by releasing pro-inflammatory cytokines. Overproduction of pro-inflammatory cytokines, including TNF-α and IL-1b, can lead to several diseases eg.,, cardiovascular diseases, joint disorders, cancer, and allergies. Emerging science suggests that whole grains may lower the markers of inflammation. Whole grains are a significant source of dietary fibres and phenolic acids that have inverse association with the risk of inflammation. The dietary fibres and phenolic acids composition of whole grains is very distinct over different grains. Whole grains (cereals and pseudo-cereals) are rich in both dietary fibres e.g., arabinoxylan, β-glucan and phenolic acids e.g., hydroxycinnamic acids, hydroxybenzoic acids, which are predominantly present in the bran layer. Although the biological mechanisms underlying widely reported association between whole grains consumption and a lower risk diseases are not fully understood. The modulatory effects of whole grains on inflammation also likely to be influenced by several mechanisms, including the effect of dietary fibres and phenolic acids, while some of these effects are direct, others involve gut microbiota, which transform important bioactive substances into more useful metabolites that moderate inflammatory signaling pathway. Thus, the aim of this review is two folded: first is to discuss the types of dietary fibres and phenolic acids commonly found in cereals and pseudo-cereals, and their health benefits observed in animal and human studies. Second, we review existing literature on the linkage between consumption of whole grains and markers of subclinical inflammation, the role of dietary fibres, phenolic acids, and gut microbiota on the anti-inflammatory activity of whole grains intake. Altogether, scientific data on the ant-inflammatory properties of whole grains are encouraging, further researches are needed to cover the gap between the emerging sciences of whole grains dietary fibres, phenolic acids and inflammation.
Human Papillomavirus Requires COPI Coat Complex for a Successful Infection.
Authors: Rahmatzada Edrees Khan , Basukala Om , Banks Lawrence
Published: March 2024

Human papillomavirus (HPV) uses the cellular trafficking machinery to reach the cell nucleus and initiate a successful infection. The HPV capsid consists of two proteins: L1 (the major capsid protein) and L2 (minor capsid protein), and L2 is known to be responsible for trafficking the viral genome to the nucleus. From previous studies, we know that many cellular proteins interact with L2 and are involved in the trafficking process at different stages of the infectious entry process. To further investigate how HPV-16 achieves successful viral entry, we have performed a mass spectrometry analysis to identify novel interacting proteins that associate with incoming HPV-16 virions. We show that HPV-16 pseudovirions interact with a group of cellular cargo proteins (COPI), and here we confirm that this is mediated by the direct binding of L2, but not L1, to the COPB1 subunit. We also show that the ability of L2 to interact with COPB1 is conserved in both low- and high-risk HPV types. Furthermore, we also show that the interaction is essential for successful infection entry of multiple HPV types, thereby identifying a novel constituent of the infectious entry pathway of the HPV.
Pre-composting of the Invasive Macrophyte Rugulopteryx okamurae – Terrestrial Isopods to Recycle Their Massive Upwellings?
Authors: Patón Daniel , José Carlos García-Gómez
Published: March 2024

Since 2015, the invasive alga Rugulopteryx okamurae has triggered the most serious marine macrophyte invasion in Europe. The removal of its huge coastal biomass generates health problems, strong odors, impact on tourism and high clean-up costs. As a circular economy strategy we propose composting with native terrestrial isopods that has not been previously tested. Therefore, specimens of Porcellio laevis were captured in urban parks and kept for 5 years in terrariums with adequate humidity and temperature control. A sample of 150 adult specimens was divided into six batches of 25 animals. Three batches were fed with organic household waste (control) and three with a 50% diet of waste and algae (treatment). P. laevis consumed up to 1.5 times their weight per day on the algae diet with little or no weight loss, but there was high mortality in both mancas and adults. However, the results are promising and we propose to encourage research with isopods because of their great voracity, high prolificacy and rusticity for the recycling of invasive algae. It should be explored in further work what percentage of R.okamurae avoids mortality by the diterpenes of the algae.
Uncovering the Role of the Early Visual Cortex in Visual Mental Imagery
Authors: Dijkstra Nadine
Published: March 2024

The question of whether the early visual cortex (EVC) is involved in visual mental imagery remains a topic of debate. In this paper, I propose that the inconsistency in findings can be explained by the unique challenges associated with investigating EVC activity during imagery. During perception, the EVC processes low-level features which means that activity is highly sensitive to variation in visual details. If the EVC has the same role during visual mental imagery, any change in the visual details of the mental image would lead to corresponding changes in EVC activity. Within this context, the question should not be whether EVC is ‘active’ during imagery but how its activity relates to specific imagery properties. Studies using methods that are sensitive to variation in low-level features reveal that imagery can recruit the EVC in similar ways as perception. However, not all mental images contain a high level of visual details. Therefore, I end by considering a more nuanced view which states that imagery can recruit the EVC, but that does not mean that it always does so.
Optimizing Healthcare Delivery: Investigating Key Areas for AI Integration and Impact in Clinical Settings
Authors: Shah Neil , Chen Henry
Published: March 2024

This study investigates the pivotal areas where Artificial Intelligence (AI) integration in healthcare warrants further exploration, leveraging insights from Boston Specialists, a forefront healthcare provider in AI adoption. Employing a qualitative case study approach, enriched by in-depth interviews and comprehensive literature reviews, we identify three main domains for potential AI expansion: scheduling efficiency, clinical documentation, and AI-driven medical research. Our results underscore the substantial enhancements AI brings to operational workflows and patient care, notably through improved scheduling systems, accuracy in medical documentation, and the facilitation of data-driven research methodologies. These findings suggest a critical need for healthcare institutions to further invest in AI technologies, focusing on these key areas to harness AI's full potential in personalizing care, optimizing efficiency, and advancing medical knowledge. The study concludes with a call for continued investigation into AI's integration within healthcare settings, emphasizing the importance of a supportive organizational infrastructure, ethical considerations, and data security in realizing AI's transformative impact on healthcare delivery and patient outcomes.
Modeling, Simulation, and Experimental Validation of Broad Input Output Range Three Voltage Level Rectifier
Authors: Oren Yarden , Dahan Eliav , Shmaryahu Aaron , Kellerman Yishai , Sitbon Moshe , Baimel Dmitry , Aharon And Ilan
Published: March 2024

A power factor correction (PFC) rectifier is compulsory for any electronic circuitry connected to the electrical grid. The majority of PFCs that are utilized are based on a step-up converter that supplies high DC voltage at its output terminal. Electric vehicle battery voltage varies from a few hundred to almost a thousand volts. Thus, an additional conversion step is obligatory when designing an all-brand universal charger. This paper presents a new type of front-end versatile step up / down three voltage level PFC. The rectifier can operate in continuous conduction mode or discontinuous conduction mode. First, the rectifier’s principle of operation is described, and then an innovative rectifier is analyzed for continuous and discontinuous conduction modes. Finally, the proposed theory is experimentally validated in a multiplier-less dual loop mode at discontinuous conduction modes. It was shown that although there is no multiplier use in the control circuitry, the power factor is near unity. It was revealed that the rectifier could swing the output voltage from 50 V to 900 V while the input voltage was 230 Vrms. The innovative topology suits any standard PFC rectifier, three-level voltage supplement, and dual-stage low-voltage power supply.
Modular Intelligent Control System in the Pre-assembly Stage
Authors: Micieta Branislav , Macek Peter , Binasova Vladimira , Dulina Luboslav , Gaso Martin , Zuzik Jan
Published: March 2024

This paper addresses the approach of fully automated intelligent control systems in production organizations, focusing on intelligent production systems research. The overview highlights a gap in control operations ahead of assembly as single-purpose control machines are frequently employed, which is precisely their drawback. Conversely, there are accurate multipurpose measurement centers that do not provide total quality control over the manufactured parts because of the cost and length of the measuring procedure. The study's primary objective was to create an intelligent modular control system, whose concept enables it to control various components. The purpose of the modular intelligent control system is to keep an eye on each module's quality during the pre-assembly phase. This system ensures exact control over the production process of modules by integrating sophisticated sensors, diagnostic tools, and intelligent control mechanisms. The technology makes it possible to monitor several parameters and important quality features. Integrated sensors and diagnostic technologies identify possible inaccuracies and disparities, guaranteeing prompt diagnosis of issues in specific modules. The system's intelligent control algorithms streamline the production process and guarantee synchronization between individual modules to achieve consistent quality and performance. One advantage of implementing the solution is that, on average, inspection time is reduced by 40 to 60% as compared to the prior manual inspection approach. In addition, full measurement data archiving was made available, and finally, the human element—which introduced a substantial error rate into this process—was removed. This system also helps to increase the project's overall efficiency, predictability, and safety while allowing for quick adjustments by standards and requirements.
Inferior Wall Double False Aneurysm as a Late Presentation of Acute Myocardial Infarction
Authors: Zelias Aleksander , Czub Pawel , Wróbel Krzysztof , Dykla Dominka , Skwarek Anna , Chrzan Iwona , Bober Maria , Urbanczyk-Zawadzka Malgorzata , Banys Pawel , Petryka-Mazurkiewicz Joanna , Kula Tomasz , Gajdosz Ryszard , Sadowski Jerzy , Dudek Dariusz
Published: March 2024

We presented unusual case of double left ventricular false aneurysm complicating late presentation AMI successfully treated with the combination of urgent surgical drainage of tamponade, staged PCI of non-culprit lesion, preventive implantation of ICD-DR, guideline directed heart failure medical therapy and delayed but effective reconstructive operation.
Evaluating Speeding Safety Performance Indicators in an Urban Area of a LMIC: A Case Study of Yaoundé, Cameroon.
Authors: Fondzenyuy Stephen Kome , Moh Mobogshikeh Divine , Tezong Steffel Ludivin Feudjio , Usami Davide Shingo , Persia Luca
Published: March 2024

In Yaoundé, Cameroon, excessive and inappropriate speeding remains a major public health concern. Part of the problem are the unsafe speed limits, lack of evidence, and effective evaluation of speeding safety performance indicators (SSPIs), and the absence of speed management, hindering the city's ability to mitigate the risks associated with speeding. This study aimed to address this knowledge gap by assessing SSPIs using a well-defined methodology and suggesting speed management strategies. Data on speed, traffic volumes and road attributes were collected from a random selection of 16 representative road sections in Yaoundé. Seven SSPIs were calculated, and weights were assigned to evaluate city-level SSPIs. The findings showed that 66.8% of drivers drive within the speed limit, generally operating at speeds of 54 km/h with a speed variation of 26 km/h. Based on the speed analysis, evidence-based strategies are proposed, and implementing these strategies could potentially reduce fatalities and serious injuries by 16% to 84% across study locations, as indicated by Elvik's model. These findings have significant policy implications for reducing speeding in Yaoundé, and the methodological approach can be replicated in other urban settings. Future research should extend SSPI evaluation to the national level and test the effectiveness of the recommended strategies.
Isothermal Nucleic Acid Amplification-Based Lateral Flow Testing for Detection of Plant Viruses
Authors: Song Xuemei , Cao Yuhao , Yan Fei
Published: March 2024

Isothermal Nucleic Acid Amplification based-Lateral Flow Testing (INAA-LFT) has emerged as a robust technique for on-site pathogen detection, providing a visible indication of pathogen nucleic acid amplification that rivals or even surpasses the sensitivity of real-time quantitative PCR. The isothermal nature of INAA-LFT ensures consistent conditions for nucleic acid amplification, establishing it as a crucial technology for rapid on-site pathogen detection. However, despite its considerable promise, the widespread application of isothermal INAA amplification-based lateral flow testing faces several challenges. This review provides an overview of the INAA-LFT procedure, highlighting its advancements in detecting plant viruses. Moreover, the review underscores the imperative to address existing limitations and emphasizes ongoing research efforts dedicated to enhancing the applicability and performance of this technology in the realm of rapid on-site testing.
Data Loss Prevention Method Based on Multiprotocol Connectivity for IoT
Authors: Takrouni Hamza , Talbi Larbi , Fouzar Youcef
Published: March 2024

The Internet of Things (IoT) is a concept based on the integration of various devices and methods of communication to exchange information in order to contribute to the improvement of everyday life, business and environment. This paper focuses on the establishment of a modern Internet of Things platform to ensure secure collection, processing and storage of data, under unexpected events. This platform establishes reliable connectivity which enhance system uptime; the key to success when implementing an IoT strategy. For this purpose, we proposed a hybrid approach combining different connectivity technologies to ensure the availability and smooth operation of the system and the prevention of data loss in unforeseen cases.
Predicting Clinical Response to Monoclonal TNF Inhibitors in Rheumatoid Arthritis: A Transcriptomic Approach Based on Transmembrane TNF Reverse Signaling and NRF2 Activation
Authors: Diallo Katy , Degboé Yannick , Baron Michel , Bellin-Robert Anais , Boyer Jean Frédéric , Constantin Arnaud , Ruyssen-Witrand Adeline , Rauwel Benjamin , Cantagrel Alain , DAVIGNON Jean-Luc
Published: March 2024

(1) Background: TNF inhibitors (TNFi) have revolutionized the treatment of rheumatoid arthritis (RA). However, 30-40 % of RA patients do not respond adequately to those biologics. In addition to neutralizing soluble TNF, TNFi have the ability to bind the transmembrane form of TNF, tmTNF. Importantly, tmTNF can act itself as a receptor that induces a “Reverse Signaling” (RS) in cells. We previously showed that certolizumab, a Fab’ TNFi, activates RS in human primary monocytes, at least in part through the transcription factor NRF2 that is known to regulate the expression of genes involved in anti-inflammatory response and oxidative stress. (2) Methods: Here, we have developed an assay for the prediction of clinical response of RA patients to TNF inhibitors. This assay is based on mRNA quantitation of CD36 activation and of 6 genes induced by NRF2 following tmTNF RS in fresh monocytes. (3) Results: We could predict the response to anti-TNF monoclonal antibodies (mAbs) with 93.3 % accuracy. However, our method was not suitable for the prediction of the response to TNF soluble receptor etanercept. (4) Conclusions: We have developed a rather simple, short-term, test that can be standardized. Predicting the response to TNF mAbs will help physicians offer the best available treatment and provide patients with personalized medicine.
Foam Control Mechanisms in Anaerobic Digestion Systems
Authors: Adisa Abidemi Olawunmi , Durrant Andy
Published: March 2024

Anaerobic digestion of waste material to biogas, with the remaining digestate slurry used as agricultural biofertilizer, is already a route of sustainable fuel production and its uptake will grow further. However, the foam layer that forms on top of the reacting mixture impedes the process and leads to liquid and solid material contaminating the gas product. Ideally, any effective foam repression should be low-cost, and react fast. Therefore, methods of optimizing anaerobic digestion need foam repression as one of the parameters in increasing gas yield. Foam can be repressed by pre-treating substrate which destroys filamentous bacteria and adding trace elements. The drawback to this method is the high cost of pre-treatment, the trace elements not being biodegradable and being toxic at high concentration; this method does not completely repress foam and is only effective under moderate organic loading
Plastics Are Paving the Way for a Greener Future and Accelerating Decarbonization
Authors: Binhazzaa Zaid
Published: March 2024

This Paper delves into the critical role played by fossil fuel-based polymers in promoting United Nations Sustainable Development Goals (SDGs) in the face of challenges brought about by swift population growth, suburbanization, and mechanization. It sheds light on the environmental and energy security recompences of converting plastic waste into biofuels and other valuable energy resources through state-of-the-art processes such as thermochemical conversion and pyrolysis. Besides, the research investigates the utilization of polymers in solar energy, energy storage, and low carbon transportation, emphasizing the inevitability of a dual approach that combines advancements in bio-based polymers and recycling technologies. It highlights the significance of collaborative endeavors involving governments, industries, and communities to overcome the technical, economic, and regulatory complications in transitioning towards a sustainable and circular plastic economy. Eventually, it showcases the potential of fossil fuel-based polymers in fostering a sustainable energy landscape, conducive to decarbonization efforts, and endorsing environmental sustainability.
Use of a Simple Stair-Climbing Test to Assess Cardiopulmonary Fitness in Clinical Practice. An Overview of the Published Liter-Ature Aiming for a Future Goal
Authors: Wander Johanna , Mall Maurice Pablo , Lentz Anne , Schrader Meike , Haas Nikolaus Alexander , Dold Simone Katrin
Published: March 2024

(1) Background: Cardiorespiratory fitness (CRF) is a prognostic factor regarding long time morbidity and mortality. To assess CRF the well-known gold standard is cardiopulmonary exercise testing (CPET), which is a time consuming and expensive test. Therefore, alternative methods for routine evaluation of CRF are needed for the general population as well as for specific patient groups such as children and young adults with congenital heart disease. The Stair Climbing Test (SCT) is a simple and resource saving test reported in the current literature. This test is used in various settings to assess different health associated risk factors including cardiorespiratory fitness, muscular resilience, therapy effectiveness or pre- and postoperative morbidity and mortality.
Risk Analysis and Visualization of Merchant and Fishing Vessels Collision In Coastal Waters
Authors: Zhu Chuanguang , Lei Jinyu , Wang Zhiyuan , Zheng Decai , Yu Chengqiang , Chen Mingzhong , He Wei
Published: March 2024

The invasion of ship domain stands out as a significant factor contributing to the risk of collisions during vessel navigation. However, there is a lack of research on the mechanisms underlying collision risks specifically related to merchant and fishing vessels in coastal waters. This study proposes an assessment method for collision risks between merchant and fishing vessels in coastal waters and validated through a comparative analysis through visualization. First of all, the operational status of fishing vessels is identified. Collaboratively working fishing vessels are treated as a unified entity, expanding their ship domain during operation to assess collision risks. Secondly, to quantify the collision risk between ships, a collision risk index (CRI) is proposed and visualized based on the severity of collision risk. Finally, taking the high risk area of merchant and fishing vessels collision in the Minjiang River Estuary as an example, this paper conduct the analysis involves classifying ship collision scenarios, extracting risk data under different collision scenarios, and visually analyzing areas prone to danger. The results indicate that this method effectively evaluates the severity of collision risk, and the identified high-risk areas resulting from the analysis is verified by accidents occurred in the recent three years.
The Mass of the Center of the Milky Way Revalued from the Fastest Orbits around the Center and the Circular Velocity Curve of the Milky Way
Authors: zhu yin
Published: March 2024

The new observations, including both the fastest star and the circular velocity curve of the Milky Way, should imply that the mass of the center of the Milky Way is almost 1011 times the mass of the Sun.
Can Music Reduce Stress and Anxiety in the Operating Room Team? An Observational Study
Authors: Rubbi Ivan , Roveri Anna , Pasquinelli Gianandrea , Cadas Claudia , Carvello Maicol , Lupo Roberto , Vitale Elsa , Conte Luana , Di Lorenzo Petia , Sangiorgi Nicola , Cremonini Valeria
Published: March 2024

Background: Music evokes positive emotions and reduces stress and anxiety. Operating Room (OR) staff face various challenges which can lead to high levels of stress. The aim of the study is to assess whether listening to music during intraoperative phases improves the work environment by reducing anxiety and stress in the entire surgical team.
Methods. A prospective observational study was conducted from February to September 2023, involving medical personnel, nursing staff, and nursing students. They were divided into two groups: Group 1 with music during surgical procedures, and Group 2 without music. Participants were administered two validated instruments: the Zung Anxiety Self-Assessment Scale (SAS) to measure anxiety, and the Positive and Negative Affect Schedule to assess emotions generating stress. Additional items were included for demographics, job satisfaction, and the organization method.
Results. Music did not impact anxiety but increased positive emotions while reducing negative ones. Music had an ancillary effect, highlighting the need for significant organizational interventions aimed at increasing operator satisfaction, including voluntary rather than mandatory assignments for nursing staff.
Conclusions. Music appears to reduce stress in the intraoperative team when supported by a positive work environment in which assigned operators have chosen to work in the OR.
Post-Translational Regulation of a Bidomain Glycerol-3-Phosphate Dehydrogenase Catalyzing Glycerol Synthesis under Salinity Stress in Chlamydomonas reinhardtii
Authors: Cruz-Powell Itzela , Subedi Binita , Kim Yeongho , Morales-Sanchez Daniela , Cerutti Heriberto
Published: March 2024

Core chlorophytes possess glycerol-3-phosphate dehydrogenases (GPDs) with an unusual bidomain structure, consisting of a glycerol-3-phosphate phosphatase (GPP) domain fused to canonical GPD domains. These plastid-localized enzymes have been implicated in stress responses, being required for the synthesis of glycerol under high salinity and triacylglycerols under nutrient deprivation. However, their regulation under varying environmental conditions is poorly understood. C. reinhardtii transgenic strains expressing constitutively bidomain GPD2 did not accumulate glycerol or triacylglycerols in the absence of any environmental stress. Although, the glycerol contents of both wild type and transgenic strains increased significantly upon exposure to high salinity. Cycloheximide, an inhibitor of cytoplasmic protein synthesis, abolished this response in the wild type. In contrast, GPD2 transgenic strains were still capable of glycerol accumulation when cultured in medium containing cycloheximide and NaCl. Thus, pre-existing GPD2 protein appears to become activated for glycerol synthesis upon salt stress. Interestingly, staurosporine, a non-specific inhibitor of protein kinases, prevented this post-translational GPD2 protein activation. Structural modeling analyses suggested that substantial conformational rearrangements, possibly triggered by high salinity, may characterize an active GPD2 GPP domain. Understanding this mechanism(s) may provide insights into the rapid acclimation responses of microalgae to osmotic/salinity stress.
Improvement of Phased Antenna Array Applied in Focused Microwave Breast Hyperthermia
Authors: Wang Xuanyu , Xi Zijun , Ye Ke , Gong Zheng , Chen Yifan , Wang Xiong
Published: March 2024

Focused microwave breast hyperthermia (FMBH) employs a phased antenna array to perform beamforming that can focus microwave energy at targeted breast tumors. Selective heating of the tumor endows the hyperthermia treatment with high accuracy and low side effects. The effect of FMBH is highly dependent on the applied phased antenna array. This work investigates the effect of polarizations of antenna elements on the microwave focusing results by simulations. We explore two kinds of antenna arrays with the same number of elements using different digital realistic human breast phantoms. The first array has all the elements’ polarization in the vertical plane of the breast while the second array has half elements’ polarization in the vertical plane and the other half in the transverse plane, i.e., cross polarization. In total 96 sets of different simulations are performed, and the results show that the second array leads to a better focusing effect in dense breasts than the first array. This work is very meaningful for the potential improvement of the antenna array for FMBH, which is of great significance for the future clinical applications of FMBH. The antenna array with cross polarization can also be applied in micro-wave imaging and sensing for biomedical applications.
Research on the International Supply Chain Management of Chinese Bamboo Weaving and Cultural and Creative Products
Authors: Sun Zhangsheng
Published: March 2024

With the increasing of China's international status and the acceleration of the process of global economic integration, the internationalization strategy of Chinese enterprises is getting deeper and deeper. This paper analyzes the problems and challenges faced by the international supply chain management of Chinese bamboo weaving and creative products, and puts forward a set of supply chain management model that ADAPTS to the international development. Firstly, the concept, connotation and types of supply chain management are sorted out through literature review. Secondly, this paper analyzes the current situation of international supply chain management of bamboo editing and creative products, and points out the existing problems. Thirdly, based on the theory and practice of international supply chain management, this paper puts forward a set of supply chain management model suitable for the international development of bamboo editing and creative products. Finally, taking a bamboo weaving and creative products enterprise as an example, the application effect of the supply chain management model is empirically analyzed. The results show that the supply chain management model can effectively reduce the cost and improve the efficiency, and is conducive to the international development of bamboo editing and creative products.