bluuebunny/crossref_metadata_2025 huggingface dataset:
Distribution and spatial-temporal variation of organic matter along the Yangtze River-ocean continuum
Authors: Zhang Shanshan , Yager Patricia L. , Liang Cui , Shen Zhiliang , Xian Weiwei
Published: July 2022

River-ocean continuums are rich environments key to the transformations of organic matter and nutrients from many sources. Human impacts on these ecosystems can be local, upstream, or global. Particulate organic matter provides one tool for exploring these processes; inventories and carbon and nitrogen stable isotopes are useful indicators. This study conducted comprehensive field investigations from the upper reaches of the Yangtze River to the coastal waters to explore the distribution and spatial-temporal variation of particulate organic carbon (POC) and nitrogen (PON), and dissolved organic carbon (DOC) in surface waters from April–May (Spring) and October–November (Autumn) 2014. Carbon and nitrogen isotopes (δ13C and δ15 N) were used to assess organic matter sources. Numerous environmental factors were also measured. PON and POC exhibited similar spatial and temporal variations along the river mainstream. POC increased from the upper to lower reaches, similarly in both seasons; POC declined seaward from the river mouth. In contrast, PON showed greater seasonal and spatial variations along the continuum, with greater primary production in offshore areas. DOC along the continuum was higher in autumn, likely related to greater river discharge and warmer waters. The DOC/POC ratios by weight were >1 in most samples except for the ones collected from the turbidity maximum zone, suggesting that DOC contributed to a larger fraction of the total organic matter inventories. End-member mixing models revealed that the proportion of organic matter from upstream (allochthonous) sources was >70% in the mainstream during both seasons. In coastal waters, the proportion of allochthonous sources was only >57%. Compared with other major world rivers, DOC and allochthonous POC are especially high in the Yangtze River-ocean continuum. Human activities causing variations in terrestrial inputs are likely an important driving factor. In addition, the contribution of soil erosion caused by urbanization to riverine organic carbon cannot be ignored.
Capturing the Civic Lives of Cities: An Organizational, Place-Based Perspective on Civil Society in Global Cities
Authors: Brandtner Christof , Powell Walter W.
Published: July 2022

Introduction to Global Perspectives special collection: The Civic Life of Cities around the World

In a wired world, how do social interactions among organizations and people continue to define civil society? Our co-produced approach to studying civil societies through a place-based, organizational lens provides fresh answers to perennial questions about voice, accountability, and embeddedness. The six articles in this collection on the civic life of cities draw on more than 1,400 interviews with organizational leaders in San Francisco, Seattle, Shenzhen, Singapore, Sydney, and Vienna. Moving beyond the “big theories” of civil society, the articles illustrate the value of our dual emphasis on place and organizations by showing how comparisons of the people, practices, and partnerships of civil society organizations enable new middle-range theories of civil society. This approach promises to offer rich comparative insights into similarities and differences among organizations around the globe.
Jubileusz 40-lecia pracy naukowej Kierownika Katedry i białostockiego zespołu historyków wychowania
Authors:   Uniwersytet w Białymstoku, Kalisz Łukasz
Published: July 2022

The article is directly related to the 40th anniversary of the Department of the History of Education, which took place on May 24–25, 2021. In the article, the author presents the speeches, congratulations and letters received by Professor Elwira J. Kryńska – the Head of the Department. The source database of the article consists of statements by representatives of the authorities, numerous professors and guests of the International Conference „Child in history – dignity and restrictions”, of which the author was a direct witness.
Dziecko w historii – pojęcie godności i poszanowania praw dziecka
Authors:   Uniwersytet w Białymstoku, Kryńska Elwira J.
Published: July 2022

Emphasizing the jubilee theme, we undertook another academic dispute devoted to the personal dignity of a child in a situation of restrictions, loss of freedom – complete dependence on others. It can include restrictions concerning various spheres of human life, for example, physical limitation, i.e. making someone’s health and life dependent on the will of another, or restrictions of the mind leading to the blurring of one’s personality, dignity due to various factors, including – as Karl Jaspers claimed – “breaking a man into two” under the influence of enormous ideological pressure. As a result, childhood, as a phenomenon affecting every human being, is still appropriated and enslaved in various ways, losing its unique, individual, subjective character, despite the fact that the humanistic approach to human existence becomes especially important and – perhaps – most needed by people today.
Ideologia w procesie kształtowania się tożsamości dziecka
Authors:   Uniwersytet w Białymstoku, Nikitorowicz Jerzy
Published: July 2022

The leitmotif of the text is the problem of a child renouncing freedom and responsibility. The author asks after JJ. Rousseau – in the name of what would the child do this? This is because different ideologies enter the dynamic and complex process of shaping the identity of a child, interacting with different forces and causing different effects. The text shows the effects of harmful ideologies and positive actions supporting the child’s identity in the past and today. The author points to the need to create an ideology of negotiation and to balance internal and external dialogue in three areas of shaping identity (inherited, individually shaped and socially conditioned) and within them in many dimensions. In the text, he presents and analyzes examples, mainly from diaries, interpreting them in the context of the Multiband and Multidimensional Identity Theory.
Konstrukcje dzieciństwa we wczesnośredniowiecznej Anglii V–XI wiek
Authors:   Uniwersytet w Northampton (Anglia), Purser Toby
Published: July 2022

Our understanding of the construct of childhood in the Middle Ages has changed in recent decades, but the history of medieval childhood remains a largely invisible theme even though almost half of the population of late medieval England was under the age of eighteen. Part of the problem is the shortage of surviving written records. This short paper looks at early medieval English law codes to examine how we can gain further understanding of childhood and children in medieval England.
Znaczenie pielęgnowania pokoju w edukacji przez nauczanie praw człowieka uczniów szkół średnich
Authors:   Uniwersytet Publiczny w Durrës (Albania), Lumani Zaçellari Manjola , Miço Heliona ,   Uniwersytet EPOKA (Albania)
Published: July 2022

The article focuses on the importance of cultivating peace through education by teaching human rights to pre-university students. It analyses the positive impact through which peace pedagogy can be integrated across curricula aiming at inducing peace through learning about human rights, values and skills. Various legal documents with an emphasis on education outline the idea that educating young people on human rights is a benefit for both individuals and society. The curriculum should therefore be oriented towards the teaching of rights, as an effective way of instilling the concept of peace and nonviolence into all subject areas and learning environments. UNESCO’s four pillars of learning include, among others, learning to live together, which is central to the development of understanding, consideration, and respect for others. It serves as the basis for ongoing peaceful coexistence. For this reason, governments of different countries have included human rights education in their national curricula. Even in Albania there has been a modest intervention in the curriculum, but there is still much room for improvement. In order to research the space given to teaching human rights in Albanian schools, we have analysed pre-university curricula. We saw that the teaching of human rights is only left to non-core subjects, such as Citizenship etc., but that is by no means enough. The curriculum should therefore, be adapted in such a way that the teaching of human rights is integrated into the core subjects, considering peace education teaching approach for the whole curriculum. Teachers, on the other hand, need to have the right competencies, skills and knowledge to integrate the teaching of human rights regardless of the subject they teach, in order to cultivate peace in their learning communities. Moreover, the Albanian government should adapt the legislation to ensure that schools teach about human and children’s rights. We strongly believe that, by developing curricula and lesson plans using peace pedagogy we would contribute to building nonviolent citizens of tomorrow.
Legal Discourse on Contract Marriage in Indonesian and Islamic Law
Authors: Izzat Akrimatil , Mulki Siti Afifah Ahmed
Published: July 2022

This study is intended to analyze the contract marriage in Indonesian Legal system and Islamic Law. The method for this study is comparative law approach. This study highlighted that marriage of contracts in Indonesia is difficult to record. Because the marriage of the contract is carried out in addition to not being recorded by formal judicial is not regulated in any regulation so it can be said that the marriage contract in Indonesia is not recognized and does not apply the law. Also, in Islamic law also does not allow the existence of contract marriage is based on the words of the Prophet Muhammad SAW. The marriage of the contract also has many consequences to the wife and the offspring of the marriage of the contract.
Hoax and Fake News by Saracen Syndicate and the Problems for National Cyber Security
Authors: Wibowo Andre Tri
Published: July 2022

Along with the times, information technology has taken an important role in society. Information technology not only has a positive impact but also has a negative impact, this is what then gives rise to an idiom that we often hear together, that information technology is like a double-edged knife. On the one hand, with the existence of information technology, it encourages demand for products. the technology itself, such as computers, modems, facilities to build internet networks and so on, then facilitates business transactions, especially financial businesses in addition to other businesses. But on the other hand, the use of information technology also invites crime. Cybercrime is a form of virtual crime by utilizing computer media that is connected to the internet and includes everything related to criminal acts.
Law Enforcement of Illegal Logging in Indonesia: Problems and Challenges in Present and the Future
Authors: Dekiawati Erla Sari
Published: July 2022

Implementation of environmental protection in juridical forest area has been regulated in Law No. 18 of 2013, on the prevention and eradication of forest destruction. In fact, the implementation of laws on the prevention and eradication of forest destruction is still at issue. Problems about efficiency and effectiveness of enforcement provided by the government. Through the methodology, it can answer the understanding of society and philosophical basis of legislation on the prevention and eradication of forest destruction and can improve the quality of enforcement of the law as well as the role given by the government. This study is expected to provide evaluation and enhancement of law enforcement in forest area protection.
Legal Politics of Indonesian Environmental Management: Discourse between Maintaining Environmental Sustainability and Economic Interests
Authors: Mahardika Ega Rijal , Bayu Muhammad Azhary
Published: July 2022

Environmental management in Indonesia has undergone various policy changes, in addition to overlapping interrelated legal regulations. Environmental management in addition to dealing with aspects of nature conservation, is also related to economic aspects, investment, and sustainable development. On the one hand there is an interest in preserving nature and protecting nature as it should be, but on the other hand there is a shift in interests, especially with regard to investment and economic interests. This study aims to analyze the political direction of environmental management law in Indonesia.
Intolerance in the Flow of Information in the Era of Globalization: How to Approach the Moral Values of Pancasila and the Constitution?
Authors: Rahma Tsania , Lemuel Yehezkiel , Fitriana Debby , Fanani Tiara Rizki Annesha , Sekarjati Rosa De Lima Gita
Published: July 2022

Indonesia is a multicultural country that has a variety of cultures. This is due to the geographical location of Indonesia which is an archipelagic country that stretches from the western end of Sabang Island to the eastern end of Merauke Island. So in conditions like this, various tribes, customs, ethnic cultures and beliefs emerged in Indonesia. This diversity has both positive and negative impacts. The positive impact is that diversity can strengthen unity, but the negative impact is that it can lead to division. One of the problems that can lead to the division of the Indonesian nation is the intolerant behavior of the people. Intolerant behavior often occurs in people's lives in various fields. The fields of politics, economics, religion, social and culture are always inseparable from intolerant attitudes, especially in the development of the flow of information in the current era of globalization. There are many cases that trigger inter-ethnic divisions that circulate in the mass media, especially social media. Therefore, a guide for the Indonesian people is needed to deal with the issue of division, namely Pancasila. Pancasila which is the nation's ideology has values ​​that become the view of life of the Indonesian people which are always relevant to the times, especially in the current era of globalization. By implementing and preserving Pancasila in all areas of people's lives, it means that we are trying to realize a common life that is conditional on the values ​​of unity, kinship, justice, tolerance and humanity.
Analysis of the Palestinian and Israeli Conflict in the Perspective of International Humanitarian Law
Authors: Mahwati Tri , Nanda Ana Risma
Published: July 2022

The conflict between Israel and Palestine to this day continues. Many studies even reveal that the conflict between Israel and Palestine is not only related to religious ideology and belief but also related to legal aspects, especially international law. This study aims to analyze the Israeli-Palestinian conflict from the point of view of International Humanitarian Law. This study finds and confirms that International Humanitarian Law can be used optimally in providing protection for civilians in times of armed conflict. However, several other related studies found that there were many violations of human rights in Palestine by the Israeli army, especially against civilians. This of course violates basic conventions on human rights and other rules of international law.
Evidence for operative treatment of talar osteochondral lesions: a systematic review
Authors: Anwander Helen , Vetter Philipp , Kurze Christophe , Farn Chui J , Krause Fabian G
Published: July 2022

Purpose

Operative treatment of talar osteochondral lesions is challenging with various treatment options. The aims were (i) to compare patient populations between the different treatment options in terms of demographic data and lesion size and (ii) to correlate the outcome with demographic parameters and preoperative scores.

Methods

A systemic review was conducted according to the PRISMA guidelines. The electronic databases Pubmed (MEDLINE) and Embase were screened for reports with the following inclusion criteria: minimum 2-year follow-up after operative treatment of a talar osteochondral lesion in at least ten adult patients and published between 2000 and 2020.

Results

Forty-five papers were included. Small lesions were treated using BMS, while large lesions with ACI. There was no difference in age between the treatment groups. There was a correlation between preoperative American Orthopaedic Foot and Ankle Society (AOFAS) score and change in AOFAS score (R = −0.849, P < 0.001) as well as AOFAS score at follow-up (R = 0.421, P = 0.008). Preoperative size of the cartilage lesion correlates with preoperative AOFAS scores (R= −0.634, P = 0.001) and with change in AOFAS score (R = 0.656, P < 0.001) but not with AOFAS score at follow-up. Due to the heterogeneity of the studies, a comparison of the outcome between the different operative techniques was not possible.

Conclusion

Patient groups with bigger lesions and inferior preoperative scores did improve the most after surgery.

Level of evidence

IV.
Methods of Tracks for Training Juniors in Olympiad Informatics: The ISIJ Experience
Authors: TSVETKOVA Marina S. , KIRYUKHIN Vladimir M. , BORISOV Nikolai A. , KINDER Mikhail I.
Published: July 2022

The article describes methodological approaches to the formation of olympiad competencies for juniors, children 12–15 years old, based on five training tracks in olympiad informatics in accordance with the IOI Syllabus. An integrated approach to the preparation of rounds for children in the framework of the experience of the International School in Informatics for Juniors (ISIJ) is also described.
Competition of State Powers During the COVID-19 Pandemic
Authors: Birmontienė Toma , Miliuvienė Jolita
Published: July 2022

The aim of this article is to analyse what kind of powers deriving from the rule of law can be extended to public authorities in response to the global COVID-19 pandemic, what is the balance of powers between the legislative and the executive whilst imposing measures controlling the virus, and what role is played by the constitutional courts whilst deliberating on constitutional disputes involving public authorities.
Public imagination as a modern mechanism of solidarization in the Ukrainian nation
Authors:   State University of Telecommunications 7, Solomianska Str., Kyiv, 03110, Ukraine, Novachenko T. V.
Published: July 2022

The article is devoted to the pressing issue of defining modern solidarity mechanisms in the Ukrainian nation, one of which is the public imagination. The methodological basis of the presented intelligence is the scientific work of C.G. Jung, the founder of one of the philosophical concepts of the collective unconscious; the work of French scientist – G. Durand, author of the concept of l’imaginaire – imaginary, who emphasizes that the world around us is the result of a free play of imagination, and modern French sociologist M. Maffesoli, – a cross-cutting problem of his research also poses the phenomenon of its social imaginary embodiment in social and symbolic forms, and several Ukrainian architects – E. Afonin, D. Zaiets, A. Martynov, V. Pliushch, V. Tancher. Based on the analysis of the presented works, the author has obtained the basis for developing a unique “ontology of the imager” – an imaginary image that is always specific. One or another “colour” of the imaginary image gives the semantic meanings that a person remembers following particular objects of reality, including political, as well as a generalized imaginary image as an ideal of actions, thoughts, feelings, and behaviour corresponding to the archetype “Self”, determining the psychological integrity of the individual. It has been confirmed that a person remembers only the most essential characteristics of an object, which constitute a “complete” imaginary image. Still they may lose touch with a particular object, retaining its typical features. This fact makes it possible to state that the type of generalized imaginary image appears as a social imaginary that influences reality creation. At the same time, due to horizontal social ties and the diversity of the individual imagination, “organic” (according to E. Durkheim) solidarity is achieved, which is a kind of strategy to mobilize society, especially in times of severe crises or threats. The public imagination is a “complete” imaginary image, which may lose touch with a particular object but retain its typical features, which allows us to determine its archetypal matrix and modern mechanism of solidarity of the Ukrainian nation.
Gaussian Volterra processes with power-type kernels. Part II
Authors: Mishura Yuliya , Shklyar Sergiy
Published: July 2022

In this paper the study of a three-parametric class of Gaussian Volterra processes is continued. This study was started in Part I of the present paper. The class under consideration is a generalization of a fractional Brownian motion that is in fact a one-parametric process depending on Hurst index H. On the one hand, the presence of three parameters gives us a freedom to operate with the processes and we get a wider application possibilities. On the other hand, it leads to the need to apply rather subtle methods, depending on the intervals where the parameters fall. Integration with respect to the processes under consideration is defined, and it is found for which parameters the processes are differentiable. Finally, the Volterra representation is inverted, that is, the representation of the underlying Wiener process via Gaussian Volterra process is found. Therefore, it is shown that for any indices for which Gaussian Volterra process is defined, it generates the same flow of sigma-fields as the underlying Wiener process – the property that has been used many times when considering a fractional Brownian motion.
Five newly recorded alien species of Hydrocotyle Tourn. ex L. (Araliaceae) in Java, Indonesia
Authors: Irsyam Arifin Surya Dwipa , Hariri Muhammad Rifqi , Peniwidiyanti Peniwidiyanti , Al Anshori Zakaria , Hutabarat Prima Wahyu Kusuma , Dewi Asih Perwita , Irwanto Rina Ratnasih
Published: July 2022

We provide the occurrence data on five newly recorded alien Hydrocotyle Tourn. ex L. species (Araliaceae) in Java, namely H. acutiloba (F.Muell.) N.A.Wakef., H. bonariensis Comm. ex Lam., H. leucocephala Cham. & Schltdl., H. tripartita R.Br. ex A.Rich., and H. verticillata Thunb. Most species were introduced as ornamental plants and naturalized in Java. Hydrocotyle acutiloba and H. tripartita might have been accidentally introduced as soil contaminants during the Dutch Colonial Era, but both species had been misidentified as H. sibthorpioides. Descriptions, a key, distribution map, and images of the species are provided.
The outcomes in children with Hirschsprung’s disease treated with transanal endorectal pull-through method
Authors:   Institute of Medical Sciences, Medical College, University of Rzeszow, Rzeszow, Poland, Szymczak Artur ,   Department of Surgery, State Hospital 2 in Rzeszow, Rzeszów, Poland, Ogorzałek Anna ,   Department of Surgery, State Hospital 2 in Rzeszow, Rzeszów, Poland, Leksa Natalia ,   Institute of Medical Sciences, Medical College, University of Rzeszow, Rzeszow, Poland, Sęk-Mastej Anna ,   Institute of Medical Sciences, Medical College, University of Rzeszow, Rzeszow, Poland, Orkisz Stanisław ,   Institute of Medical Sciences, Medical College, University of Rzeszow, Rzeszow, Poland
Published: July 2022

Introduction and aim. The evaluation of functional results, complications and problems of children with Hirschsprung’s disease treated with one-stage surgery (TEPT) or two-stage surgery (colostomy, TEPT) in Paediatric Surgery Clinic in Rzeszow. Material and methods. Medical documentation of 41 children treated due to Hirschsprung’s disease in years 2006-2018 in Rzeszow were retrospectively analysed. The results of the questionnaires conducted among the parents of operated children were surveyed. Results. The average time of the radical surgery was 189 minutes. The mean length of the resected intestine in the classic form was 19 centimeters, in long-segment 35 centimeters. In the post-operative period, 15 patients had a blood transfusion. The mean time of the children’s stay calculated from the date of surgery until the discharge equaled 13.4 days. Early post-operative complications: enterocolitis occurred in 6 patients (1 death in a septic shock mechanism), total dehiscence of anastomosis in 1 patient, abscess of perirectal space in 1 patient, anastomotic retraction in 1 patient and in 3 patients inaccurate intra-operative evaluation of the section (intra), buttock dermatitis appeared in all patients. Late post-operative complications (a control trial of 38 patients): Soiling was confirmed in 9 patients, periodic constipation in one. The abnormal consistency of stool was signaled in 3 children. Two children were repetitively hospitalized due to enterocolitis. The frequency of defecation almost in all patients was reduced after a three, four-month period since the operation from 10-15 per day to the age norm. In one child, where the retraction of the anastomosis was diagnosed, the soiling and heightened frequency of defecation throughout the day persists. All of the parents of the older children view the outcome of the surgery as positive and the life quality of their children does not differ from their peers. Conclusion. TEPT is a method which can be performed in newborns, infants, babies as well as in case of a long-segment aganglionosis. Barium enema is not reliable in evaluation of the length of the aganglionic section in the long-segment type of Hirschsprung’s disease. The treatment of choice in the early post-operative enterocolitis should be colostomy. Worse functional results were observed in children after two-stage treatment – especially, in cases where the colostomy was created due to the intestinal re-distention.
EXPERTS COUNCIL RESOLUTION. RESULTS OF MPS I PATIENTS MONITORING. CRITERIA FOR ERT TREATMENT RE-INITIATION IN MPS I AFTER HSCT
Authors: Editorial Article
Published: July 2022

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Leptin and Epicardial Fat: New Markers of Psoriasis in Children? Prospective Cross-Sectional Study
Authors: Ambarchyan Eduard T. , Namazova-Baranova Leila S. , Murashkin Nikolay N. , Vishneva Elena A. , Revunenkov Grigoriy V. , Ovsyanik Natalya G. , Ivanchikov Vladislav V. , Kuzminova Anastasia D.
Published: July 2022

Background. Psoriasis is a polygenic multifactorial immune-mediated disease. Its course can be aggravated by associated obesity. Recently, there is negative trend that is characterized by the increase in the number of moderate to severe psoriasis cases among children, and majority of them have obesity. Identification of factors that that are relevant in these two conditions will allow us to improve and optimize the genetically engineered biological therapy for this category of patients.

Objective. The aim of the study is to evaluate epicardial adipose tissue thickness, serum leptin levels, eating behavior via the data from Children’s Eating Behaviour Questionnaire (CEBQ) for patients with psoriasis and obesity, and compare the results with control group – patients with psoriasis and no associated obesity.

Results. We have studied 12 patients with established diagnosis of psoriasis, 5 of them had diagnosis of obesity. Epicardial fat thickening was revealed in 20% of cases in the study group (patients with psoriasis and obesity), and no epicardial fat thickening was revealed in the control group. The increase in serum leptin was revealed in 100% of cases in obese patients with psoriasis, and only in 14% of cases in the control group. The mean leptin level in obese patients was 16.65 ng/ml, in the group with normal body weight – 7.08 ng/ml. Obese patients have shown higher values in “food approach” scales group in comparison to normal weight patients.

Conclusion. Patients with obesity and psoriasis has shown elevated leptin levels, higher incidence of epicardial fat thickening, and tendency to develop abnormal eating behavior.
Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration
Authors: Vandenbroucke Jan P. , Von Elm Erik , Altman Douglas G. , Gotzsche Peter C. , Mulrow Cynthia D. , Pocock Stuart J. , Poole Charles , Schlesselman James J. , Egger Matthias
Published: July 2022

Much medical research is observational. The reporting of observational studies is often of insufficient quality. Poor reporting hampers the assessment of the strengths and weaknesses of a study and the generalisability of its results. Taking into account empirical evidence and theoretical considerations, a group of methodologists, researchers, and editors developed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) recommendations to improve the quality of reporting of observational studies. The STROBE Statement consists of a checklist of 22 items, which relate to the title, abstract, introduction, methods, results and discussion sections of articles. Eighteen items are common to cohort studies, case-control studies and cross-sectional studies and four are specific to each of the three study designs. The STROBE Statement provides guidance to authors about how to improve the reporting of observational studies and facilitates critical appraisal and interpretation of studies by reviewers, journal editors and readers. This explanatory and elaboration document is intended to enhance the use, understanding, and dissemination of the STROBE Statement. The meaning and rationale for each checklist item are presented. For each item, one or several published examples and, where possible, references to relevant empirical studies and methodological literature are provided. Examples of useful flow diagrams are also included. The STROBE Statement, this document, and the associated Web site (http://www. strobe-statement.org/) should be helpful resources to improve reporting of observational research. Present article is Russian-language translation of the original manuscript edited by Doctor of Medicine R.T. Saygitov.

Present translation was first published in Digital Diagnostics. doi: 10.17816/DD70821. It is published with minor changes related to the literary editing of the translation itself.
Experience of Long-Term (9 Years) Administration of Tocilizumab in Female Patient with Systemic Onset Juvenile Arthritis: Case Study
Authors: Kaleda Maria I. , Nikishina Irina P. , Pachkoria Tamara N.
Published: July 2022

Background. Systemic onset juvenile arthritis is a chronic disease of childhood. Its severity is determined by systemic manifestations, high risk of complications, such as macrophage activation syndrome, interstitial lung disease, and persistent polyarthritis with severe functional disorders. Genetically engineered biological drugs administration significantly improves the prognosis in these patients, thus, there are many questions about the possibilities of successful treatment correction in order to maintain long-term remission in real clinical practice.

Clinical case description. The results of long-term (9 years) administration of tocilizumab in female patient with early onset of systemic onset juvenile arthritis are presented. It has been shown that control over disease activity can be achieved via adjusting the drug dosage and the intervals between infusions.

Conclusion. Tocilizumab significantly improves prognosis of patients with systemic onset juvenile arthritis at good safety profile of this treatment.
The clinical case: COVID-19 in a child with chronic kidney disease
Authors: Ermolaeva Yuliya A. , Samoilova Yu. G. , Oleynik O. A. , Kudlay D. A.
Published: July 2022

Since the spread of the novel coronavirus infection, most researchers have noted a low proportion of sick children in general pediatric cohort compared to adults, who had a mild disease course and rare complications. The most frequent clinical manifestations of the disease are respiratory and, some less frequently diarrheal syndromes. The disease has predominantly mild or asymptomatic course. The risk of adverse outcomes in children, similar to adults, clearly correlate with the presence of background chronic pathology. The need for respiratory support prevails in children with a severe premorbid burden. Here, a clinical case of ongoing novel coronavirus infection in adolescent patient comorbid with chronic kidney pathology is described. In adolescence, the patient was diagnosed with mesangioproliferative glomerulonephritis (IgA-nephropathy), and further registered at the dispensary receiving a combination therapy with angiotensin converting enzyme inhibitors and disaggregation drugs. The epidemiological history contained no established contacts with infectious patients. The clinical manifestations of COVID-19 in the patient are represented by catarrhal and diarrheal syndromes, transient renal dysfunction in the acute period of the disease. The onset of coronavirus infection was clinically characterized by symptoms of damaged gastrointestinal tract and was considered as acute gastroenteritis of infectious etiology. Empirically prescribed antibacterial therapy in combination with antiplatelet agents and symptomatic drugs had no effect. The diagnosis of the novel coronavirus infection was verified only on day 4 of hospitalization, clinical and laboratory signs of lung damage emerged. The inflammatory process developed in the patient lungs was secondary to the main pathology. The severity of the patients condition was determined by the presence of respiratory and renal insufficiency. Lung damage with minimal severity complaints and clinical data had a bimodal pattern and required respiratory support. A comprehensive approach to treatment, including respiratory, antiviral, enterosorption, anticoagulation, anti-inflammatory, antihypertensive, hepatoprotective, symptomatic therapy with change in antibacterial drugs allowed to achieve positive dynamics. On day 12 of the illness, the patient required no respiratory support. The presence of symptoms of gastrointestinal tract damage in COVID-19 necessitates the mandatory inclusion of PCR assay for SARS-CoV-2 into diagnostic protocol in patients with diarrheal syndrome to perform etiological disease interpretation.
Comparative analysis of strategies of Chinese companies in the digital economy
Authors: Novikova I. V. , Xie Kunchao
Published: July 2022

With the progress of science and technology, the world is experiencing rapid digital transformation, new technologies and new business models are developing, digital technology and traditional industries are expanding their integration and involvement levels, and the economies and societies of various countries are increasingly entering the digital age. The overall scale of the world’s digital economy continues to grow, and the proportion of the digital economy is increasing, but the development between regions is uneven, and the problem of the digital divide is highlighted. The level of digital economic development is highly related to the overall level of economic development. The overall level of digital economy development in advanced economies is higher, the digital economy is larger, and the digital economy accounts for a higher proportion of the total domestic economy. It has entered a highly digitized stage, and the world’s major Internet companies and high-tech companies are also highly concentrated in these countries and regions. The article presents the results of a comparative analysis of the strategies of Chinese companies in the digital economy. The work was written in accordance with the strategy methodology of the Foreign Member of the Russian Academy of Sciences (Life-time), Dr.Sci. (Econ.), Professor Vladimir L. Kvint. The author pays considerable attention to the current state and forecasts of the digitalization of the Chinese economy, the connection between digital transformations and the growing need of the population to improve technologies that simplify their life. Based on statistical data, the author determines the advantages and disadvantages of existing digital technologies, states the deepening of their integration with the industrial sector. Analyzing the strategies of the largest digital campaigns, the author reveals the dynamics of the use of applications developed by them by citizens. In conclusion, a conclusion is made about the importance and rapid spread of digital technologies, as well as the need for states interested in their development to create conditions for the latter.
Strategic analysis of labour market of the Amur region (data taken form HeadHunter and SuperJob web-platforms)
Authors: Shevchenko K. V.
Published: July 2022

The article presents strategic analysis of labour market of the Amur region using the data taken from HeadHunter and SuperJob web-platforms. The analysis can be regarded as an important component of strategizing the employment of the population of the region. According to the theory of strategy and methodology of strategizing Vladimir Kvint, the final goal of the implementation of any strategy (global, national, regional, sectoral, corporate and personal) is improvement of the quality and standard of human life. Identifying interests in developing employment of the regional population is the most important stage of strategizing because finding out the real situation can make it possible to establish the priorities that will both correspond with the trends and meet the needs of the employment of the regional population. To conduct strategic analysis of labour resources of the Amur region the author makes use of the theory and methodology of strategizing by Vladimir Kvint. According to the theory strategic analysis involves examining internal and external factors of the object of strategizing. The external factors include global, national, regional and sectoral trends. To analyze internal factors affecting the development of labour resources of the Amur region the author analyzed the information about vacancies in the companies and resumes of the applicants located in the region. The information was taken from the largest employment web-platforms in Russia – HeadHunter and SuperJob. One of the most popular methods of labour market analysis abroad is analyzing employment web-platforms. This method involves such positive features as efficiency, data accessibility and large population size which provides the opportunity to make representative sample.
The role of intellectual property rights' protection in advancing development in South Africa
Authors: Chidede Talkmore
Published: July 2022

Notwithstanding some debate, intellectual property remains a necessary tool for social, cultural, economic, and technological development in the 21st century. In this century, the global economy is driven by knowledge and technology, and the market is increasingly recognising intellectual property as a valuable commercial asset and a force for technological innovation. South Africa, among other countries, recognises the role of intellectual property rights in several policy measures related to development, trade, and industrialisation. This article seeks to highlight the significant role of intellectual property rights protection in advancing social, economic, technological, and cultural development in South Africa.
El origen sensorial de la conciencia en la narrativa colombiana (1870-1920)
Authors:   Universidad EAFIT, Salazar Martínez Carlos Andrés
Published: July 2022

A finales del siglo XIX tuvo lugar una revolución de iguales proporciones a la que supuso apartar la Tierra del centro del universo. La idea de que el cuerpo humano –concebido a través de procesos fisicoquímicos– sea examinado como un elemento más de la naturaleza y que la conciencia –vinculada al funcionamiento del sistema nervioso– sea entendida como el resultado de experiencias sensoriales suscitó un proceso mediante el cual fue puesta en duda la influencia absoluta de los designios divinos sobre la existencia humana. De esta manera, los estudios experimentales de los fenómenos de la vida humana y la conciencia despojaban al ser humano de beneficios como la vida eterna y el libre albedrío. Este libro analiza y explica la manera en que dichas ideas hicieron tránsito por el campo intelectual y académico de Colombia hasta ocupar un espacio en las obras literarias, el tipo de postura que se adoptó y la clase de dinámicas que suscitó la recepción de esta nueva forma de interpretar y representar al ser humano y la conciencia a nivel narrativo y estético.
Chia (Salvia hispanica) seeds degradation studied by fuzzy-c mean (FCM) and hyperspectral imaging and chemometrics - fatty acids quantification
Authors: Cruz-Tirado J. P. , Lopes de França Pedro Renann , Fernandes Barbin Douglas
Published: July 2022

Chia seeds are nutritious food because they have a high content of protein, polyunsaturated fatty acids (omega-3 and omega-6) and phenolic compounds. During storage, fatty acids are degraded, by oxidative and hydrolytic reactions, forming free fatty acids (FFA). In this work, we used Near Infrared Hyperspectral Imaging (NIR- HSI) and chemometrics to predict FFA acid value and fatty acids concentrations in chia seeds during storage. First, we explore the hyperspectral images by Fuzzy c-means (FCM), where it is possible to observe as chemical compounds are formed or degraded during storage. Second, PLSR models were developed to predict FFA value and fatty acids concentration. RPD values reached values higher then 2.0, indicating a good ability to estimate these chemical compounds, especially polyunsaturated fatty acids omega-3 and omega-6. Finally, NIR-hyperspectral imaging coupled with chemometrics allowed us to show the chemical degradation process of chia seeds during storage, mainly associated with polyunsaturated fatty acids degradation. Besides NIR-HSI showed to be a powerful technique to quantify the main fatty acids with high accuracy.
Prevalence of Psychopathology in Bariatric Surgical Candidates with Type 2 Diabetes Mellitus: Systematic Review
Authors: Pekin C , McHale M , Byrne G
Published: July 2022

Introduction: Bariatric surgical candidates confer an elevated risk of psychopathology. Prior reviews highlight the vulnerability and bidirectionality of psychopathology in people with Type 2 Diabetes Mellitus (T2DM). Despite this, current evidence for the rates of psychopathology in people with T2DM pre and post-bariatric surgery has yet to be systematically reviewed. Objective: To perform a systematic review of the prevalence of psychopathology in adults with Type 2 Diabetes Mellitus pre and post-bariatric surgery. Results: Seven studies fulfilled the inclusion criteria, from 45,576 studies on the digital search of databases. Conclusions: Scant evidence exists which specifies cohorts of bariatric surgical patients with T2DM and rates of psychopathology. Further research is warranted to understand the risks, measures, and potential interventions for this subgroup.
[RETRACTED] Purvana Skin Care Cream Reviews! v1
Authors: Cream RevSkin
Published: July 2022

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Purvana Skin Care Cream Reviews!
[RETRACTED] Keto FBX Reviews : Expert Opinions & Legit Reviews! v1
Authors: not provided IdaPecoraro
Published: July 2022

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Keto FBX: There's a new weight loss product on the market calledKeto FBX. This product is designed to help you lose weight and boost ketone levels,...
[RETRACTED] FRANCEVia Keto Gummies ViaKeto Capsules France Revue Exposée 2022! Faux ou réel? v1
Authors: G G
Published: July 2022

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[RETRACTED] truly keto gummies v1
Authors: not provided josephfragland
Published: July 2022

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[RETRACTED] What Is The GoKeto Gummies & Does It Use Make You Loss Weight Faster? v1
Authors: Gummies GoKeto
Published: July 2022

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https://www.outlookindia.com/outlook-spotlight/goketo-gummies-reviews-shark-tank-alert-goketo-bhb-pills-price-website--news-206010
[RETRACTED] What Condor CBD Gummies Reviews [Shark Tank Warning]: Real Cost & Brand Products Special Offer? [EXPOSED] Price? v1
Authors: not provided condorcbdgummies
Published: July 2022

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#Condor_CBD_Gummies_Reviews #Shark_Tank_Warning #Cost & Brand Products Special Offer
Study_Protocol_English_Wintermann_V2 v1
Authors: not provided gloria.wintermann
Published: July 2022

Objectives: Patients with Panic Disorder (PD) show an abnormal stress-induced functioning of the Hypothalamic-Pituitary-adrenal (HPA)-axis. Different protocols for stress induction are of rather low relevance for the psychotherapeutic treatment. In practice, interoceptive exposure is often realized as Low Intensity Exercise (LIE), as compared to an incremental cycle exercise test to exhaustion. Currently, it is not known, whether LIE displays an effective interoceptive stressor 1.) leading to a significant anxiety induction; 2.) a comparable HPA- and Sympathetic-Adreno-Medullar (SAM)-axis response in both patients and healthy controls; 3.) stress responses under LIE are associated with treatment outcomes. Patients and methods: N = 20 patients with PD and n = 20 healthy controls were exposed to ten minutes of LIE on an exercise bike. LIE was applied as part of the interoceptive exposure, during an intensive Cognitive-Behavioral Therapy (CBT) in a day clinic. Heart rate was monitored and salivary cortisol samples collected. Before and after the LIE, state anxiety/ arousal were assessed. In order to evaluate psychopathology, the Panic and Agoraphobia Scale, Mobility Inventory, Agoraphobic Cognitions Questionnaire and Body Sensations Questionnaire were applied, before (T1) and after five weeks (T2) of an intensive CBT. Results: LIE led to a significant and similar heart rate increase in both groups. Cortisol decreased over time in both groups, especially in male patients. A higher psychopathology before, and after CBT, was associated with a significantly lower cortisol response under LIE. Conclusions: In the present study, LIE led to a divergent stress response: while there was a significant heart rate increase, cortisol decreased over time, particularly in male patients. A lower reactivity of the HPA-axis seems to be associated with a lower treatment outcome, which may affect extinction based learning. The findings suggest, that interoceptive stimuli should be designed carefully in order to be potent stressors.
[RETRACTED] Keto Pro Gummies v1
Authors: Pro Gummies Keto
Published: July 2022

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Keto Pro Gummies Working together with a registered dietitian can make sure you follow this diet in a healthy manner without increasing your risk for complications or negative side effects. Following a strict diet for weight loss and then quickly reverting to old habits when the dietary changes are too restrictive can lead to what is known as weight cycling,
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Authors: not provided masterofseo
Published: July 2022

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(Main Buy Link & Reviews) @>> https://www.outlookindia.com/outlook-spotlight/via-keto-gummies-australia-reviews-chemist-warehouse-via-keto-apple-gummies-australia-is-it-scam-or-legitimate--news-205185
[RETRACTED] Herba Rx Keto Reviews (Working Or Hoax) Works To Release Stored Fat v1
Authors: not provided grnopartesale
Published: July 2022

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Herba RX Keto is a weight loss supplement designed to mimic the effects of a ketogenic diet without necessity embarking on the diet. https://herba-rx-keto-pills.jimdosite.com