bluuebunny/crossref_metadata_2025 huggingface dataset:
ОЦЕНКА КАРДИОВАСКУЛЯРНОГО РИСКА И ОБЪЁМА ПОРАЖЕНИЯ ЛЕГКИХ У БОЛЬНЫХ, УМЕРШИХ ОТ ПНЕВМОНИИ, АССОЦИИРОВАННОЙ С COVID-19
Authors: Есетова Г.У. , Идрисова Л.Р. , Серикбаева А.К. , Жамирова Р.Н. , Муминов Т.А.
Published: September 2024

COVID-19 – это вирусная инфекция, которая вызывают тяжелую пневмонию и сопряжена с высокой летальностью, особенно среди пожилых людей. Целью нашей работы было выявить факторы риска летальности от COVID-19. Материалы и методы Мы проанализировали 100 историй болезней умерших от пневмонии, вызванной COVID-19, в разгар пандемии. У всех больных наличие короновирусной инфекции было подтверждено полимеразной цепной реакцией (ПЦР), диагноз пневмонии выставлен на основании данных компьютерной томографии (КТ), средний возраст 70,2±13,4 лет, число мужчин 46 и женщин 54, средняя продолжительность госпитализации 10,2± 6,7 дней. Все больные не получали вакцину против COVID-19. Полученные результаты Факторы риска смертности от пневмонии, вызванной COVID-19, включают пожилой возраст, сопутствующие заболевания с высоким сердечно-сосудистым риском и обширное поражение легких.
СЛУЧАЙ ПОЗДНЕГО ВЫЯВЛЕНИЯ ТУБЕРКУЛЕЗНОГО МЕНИНОЭНЦЕФАЛИТА У РЕБЕНКА (НАБЛЮДЕНИЕ ИЗ ПРАКТИКИ)
Authors: Арымбаева А.Б. , Нуралбаева П.К. , Бекбенбетова З.С.
Published: September 2024

В статье приведен пример клинического случая позднего выявления туберкулезного менингоэнцефалита, который привел к глубокой инвалидности ребенка. Описаны допущенные ошибки в ходе диагностики на уровне ПМСП и частных медицинских центров. В настоящее время в связи с внедрением генно-молекулярных методов диагностика туберкулезной инфекции не занимает длительное время, но проблема своевременного выявления на уровне ПМСП остается еще актуальной. Первые признаки туберкулеза головного мозга, его оболочек, на уровне ПМСП и стационаров трактуются неправильно и недооцениваются, что приводит к ухудшению состояния пациентов и к серьезным последствиям. Основные проблемы связаны с отсутствием настороженности у врачей-клиницистов.
Organozinc reagents in solution: insights from ab initio molecular dynamics and X-ray absorption spectroscopy
Authors: RIO Jordan , PESSEMESSE Quentin , CASCELLA Michele , PAYARD Pierre-Adrien , PERRIN Marie-Eve L.
Published: September 2024

Organozinc reagents play a critical role in synthesis, yet our comprehension of their structure-reactivity relationships is limited by a lack of information about their structures in solution. This study introduces a computational workflow, validated by X-ray absorption spectroscopy, to investigate organozinc reagents in solution. The solvation states of ZnCl2, ZnMeCl and ZnMe2 were explored using ab initio molecular dynamics (metadynamics and Blue Moon sampling) within an explicit solvent cage. The study revealed the existence of various solvation states at room temperature, providing clarity on the previously debated structure of ZnMe2 in THF solution. These findings were confirmed by near- edge X-ray absorption spectroscopy (XANES) interpreted using time-dependent density functional theory (TD-DFT) calculations.
Controlled quantum well formation on DNA-wrapped carbon nanotubes via peroxide-mediated aryl diazonium reduction
Authors: Piletsky Stanislav , Keblish Erin , Heller Daniel
Published: September 2024

Quantum well defect-modified single walled carbon nanotubes are environmentally sensitive nanomaterials with wide-ranging applications in biosensing, imaging, light harvesting, quantum computing, energy storage and catalysis. The most common method for covalent functionalization of nanotubes for biosensing applications involves reactions with aryl diazonium salts to generate sp3 aryl defect sites, commonly followed by wrapping with single stranded DNA. We describe herein a rapid aryl diazonium functionalization reaction directly compatible with DNA-wrapped nanotubes. The reaction uses mild aqueous conditions at physiological pH and can be easily monitored in real-time via fluorescence analysis to control the degree of functionalization. Overall, this reaction greatly simplifies the production of covalently functionalized DNA-wrapped carbon nanotubes, expanding their potential for industrial and biomedical applications.
Steric Stabilization of Colloidal UiO-66 Nanocrystals with Oleylammonium Octadecylphosphonate
Authors: Park Sungho V. , Bhai Lakshmi , Lee Gahyun Annie , Park Ah-Hyung A. , Marbella Lauren E. , Owen Jonathan S.
Published: September 2024

We report the synthesis and characterization of octahedral UiO-66 nanocrystals (d = 17–25 nm) terminated with amine, oleate, and octadecylphosphonate ligands. Acetate capped UiO-66 nanocrystals were dispersed in toluene using oleic acid and oleylamine. Ligand exchange with octadecylphosphonic acid produces ammonium octadecylphosphonate terminated nanocrystals with coverages of 2.6–3.2 chains nm-2 that stabilize colloidal dispersions in nonpolar solvents. Solution phase 1H and 31P nuclear magnetic resonance (NMR) spectra of the linkers and surface ligands display line shapes that are broadened by slow tumbling of the nanocrystals. Octadecylphosphonate functionalized MOFs have up to ~30% carbon dioxide absorption capacities compared to bulk UiO-66 after correcting for the ligand mass. These results illustrate the intriguing perspective that MOF nanocrystals can be characterized and manipulated like a macromolecular complex and represent an important milestone in the nascent field of MOF surface science.
Nickel (II) Tetradentate Complexes Bearing NHC-Pyridyl Derived Ligands for Photocatalytic Carbon Dioxide Reduction
Authors: Manafe Sonya , Olajide Gbolagade , Boudreaux Chance , Qu Fengrui , Whitt Logan , Pridemore Patrick , Hall James Fletcher , Szilvasi Tibor , Papish Elizabeth
Published: September 2024

Nickel (II) complexes bearing tetradentate NCCN ligands comprised of optionally protic pyridine and N-heterocyclic carbene (NHC) donors have been synthesized and used as catalysts for carbon dioxide reduction. These complexes were synthesized bearing OMe, OBn, or OH substituents on the pyridine rings and were characterized by 1H NMR, 13C NMR, UV-Vis, IR, HR-MS, and single crystal X-ray diffraction. The OH substituent was partially deprotonated as shown by the crystal structure. Electrochemical studies show that these nickel complexes undergo two electron reduction events prior to CO2 reduction. Catalytic current enhancement under CO2 relative to N2 is not observed under dry conditions, but the addition of proton sources leads to modest current enhancement (icat/ip < 2). Visible light driven photochemical CO2 reduction with a photosensitizer (Ir(ppy)3 where ppy = 2-phenylpyridine) and sacrificial electron and proton donors was studied, and formate is the major product with ~10:1 formate to CO production. Electron donor groups (OMe, OBn, OH) do not enhance formate production (relative to H analog), and CO production is only slightly enhanced. Overall with Ni(II), the tetradentate ligands are comparable to recently published pincer ligands for sensitized CO2 reduction, but pincer ligands offer a clear advantage in self-sensitized catalysis.
Coupling online size exclusion chromatography with charge detection-mass spectrometry using Hadamard transform multiplexing
Authors: Sanders James , Owen October , Tran Brian , Mosqueira Jeffrey , Marty Michael
Published: September 2024

Charge detection mass spectrometry (CD-MS) is a powerful technique for the analysis of large, heterogeneous biomolecules. By directly measuring the charge states of individual ions, CD-MS can measure the masses from spectra where conventional deconvolution approaches fail due to the lack of isotopic resolution or distinguishable charge states. However, CD-MS is inherently slow because hundreds or thousands of spectra need to be collected to produce adequate ion statistics. The slower speed of CD-MS complicates efforts to couple it with online separation techniques, which limit the number of spectra that can be acquired during a chromatographic peak. Here, we present the application of Hadamard transform multiplexing to online size exclusion chromatography (SEC) coupled with Orbitrap CD-MS, with a goal of using SEC for separating complex mixtures prior to CD-MS analysis. We developed a microcontroller to deliver pulsed injections from a large sample loop onto a SEC for online CD-MS analysis. Data showed a series of peaks spaced according to the pseudo-random injection sequence, which were demultiplexed with a Hadamard transform algorithm. The demultiplexed data revealed improved CD-MS signals while preserving retention time information. This multiplexing approach provides a general solution to the inherent incompatibilities of online separations and CD-MS detection that will enable a range of applications.
Plasmon-enhanced multiphoton polymer crosslinking for selective modification of plasmonic hotspots
Authors: Morozov Yevhenii , Quilis Nestor Gisbert , Fossati Stefan , de Laporte Laura , Gusenbauer Claudia , Weber Andreas , Toca-Herrera Jose Luis , Wiesner (née Diehl) Fiona , Jonas Ulrich , Dostalek Jakub
Published: September 2024

A novel approach to selectively modify narrow sub-areas of metallic nanostructures adjacent to plasmonic hotspots, where strong electromagnetic field amplification occurs upon localized surface plasmon (LSP) excitation, is reported. In contrast to plasmon-driven polymerization, it relies on plasmonically enhanced multiphoton crosslinking (MPC) of polymer chains carrying photoactive moieties. When attached to metallic nanostructures and irradiated with a femtosecond near-infrared beam resonantly coupled with LSPs, the enhanced field intensity locally exceeds the threshold and initiates MPC at plasmonic hotspots. This concept is demonstrated using gold nanoparticle arrays coated with two specifically designed polymers. Local MPC of a poly(N,N-dimethyl acrylamide)-based copolymer with an anthraquinone crosslinker is shown via atomic force microscopy. Additionally, MPC is tested with a thermoresponsive poly(N-isopropyl acrylamide)-based terpolymer. The reversible thermal collapsing and swelling of the MPC-formed hydrogel at specific nanoparticle locations are confirmed by polarization-resolved LSPR spectroscopy. These hybrid metallic/hydrogel materials can be further post-modified offering attractive characteristics for future spectroscopic/bioanalytical applications.
Water-induced Switching in Selectivity and Steric Control of Activity in Photochemical CO2 Reduction Catalyzed by RhCp*(bpy) Derivatives
Authors: Lee Dongseb , Yamauchi Kosei , Sakai Ken
Published: September 2024

Photocatalytic reduction of CO2 to formic acid (HCOOH) was investigated in either organic or aqueous/organic media by employing three water-soluble [RhIIICp*(LH2)Cl]+ (LH2 = n,n’-dihydroxy-2,2’-bipyridine; n = 4, 5, or 6) in the presence of [Ru(bpy)3]2+, 1,3-dimethyl-2-phenyl-2,3-dihydro-1H-benzo[d]imidazole (BIH) and triethanolamine (TEOA). Through studying the electron-donating effects of two hydroxyl groups introduced to the bipyridyl ligand, we found that the substituent positions greatly affect both the catalytic efficiency and selectivity in CO2 reduction. More importantly, the HCOOH selectivity shows a dramatic increase from 14% to 83% upon switching the solvent media from pure organic to aqueous/organic mixture, where the H2 selectivity shows a reverse phenomenon. The enhanced HCOOH selectivity and the drastic decrease in the H2 yield are well rationalized by the fact that the catalytic CO2 hydrogenation is not only driven photochemically via the attack of RhIII(H)Cp*(LH2-•) on CO2 but also partly bypassed by a dark H2 addition reaction yielding [RhIII(H)Cp*(L)]- from [RhIIICp*(L)Cl]+, which was also separately investigated under the dark conditions. Combination of experimental and theoretical approaches were made to clarify the pKa values of catalyst intermediates together with the abundant species responsible for the major catalytic processes. Our DFT studies unveil that the exceptionally large structural strain given by the steric contacts between the 6,6’-dihydroxyl groups and the Cp* moiety plays a significant role in bringing about an outstanding catalytic performance of the 6,6’-subsituted derivative. The intrinsic reaction coordinate calculations were carried out to clarify the mechanism of hydride transfer steps leading to generate formate together the heterolytic H2 cleavage steps leading to afford the key hydridorhodium intermediates. This study represents the first report on the water-induced high selectivity in CO2-to-HCOOH conversion, shedding a new light on the strategy to control the efficiency and selectivity in the catalysis of CO2 reduction.
Ecological problems of the plant cover of the northeastern slope of Great Caucasus (within Azerbaijan)
Authors: Hajiyeva Gülnar Nuru
Published: September 2024

Highlight the purpose. Plant cover of our republic, especially forest ecosystems, has lost its original state as a result of the influence of natural and anthropogenic factors. The study of the impact of these factors on biodiversity has been the focus of many experts. The settlement of the studied area since ancient times and the good development of agriculture have caused the degradation and erosion of the forest cover that covers large areas, as well as the vegetation that replaces each other in the altitude zones here. For this reason, the issues of protection and protection of vegetation are distinguished by their relevance. The main goal of our research is to protect the vegetation of forests that have changed their initial state. Objectives. Mountain geosystems of the northeastern slope of the Greater Caucasus are bordered by the Russian Federation to the north, northwest, and west, the Samur-Devachi plain to the east, and the watershed line of the Greater Caucasus Range and Atachay to the south and southeast. Methods. Field studies were organized to solve the issues raised during the research period. Short-term visual observations of the existing geoecological conditions were carried out, from topographic maps and other maps (landscape, vegetation, etc.) of various scales, as well as from 1:25000 scale aerial and space images in the fund of the Institute of Ecology of MAKA, “Google” and “Bing” space images with a resolution of 1 meter in the funds, taken in the visible zone of the spectrum, obtained from various satellites in 2020-2023 and based on the application of SASPlanet, ArcGIS processing programs were used. With the help of these materials, the vegetation degradation and erosion processes of the research area were studied. Results. The northeast part of the Great Caucasus differs from the other mountainous regions for its appropriation features. For a long time appropriation of the investigated zone by the various farming areas caused a serious change in the natural geosystems. Thus, the zones where a hypsometric height of 200-500 m are mainly replaced by agro-complexes, the parts within 500-1800 m turned into a life and rest objects together with the arable and pastures, an irregular use from the summer pastures in cattle-breeding in the zones higher than 1800 m was completed by exposing of the plant cover to transformation. During assimilation, activation of ecological problems like decreased plant productivity, intensification of the erosion process, acceleration of degradation, and so on activates a problem of rational use. Defining importance, sensitiveness of plant cover, and rational use ways as protection, refusal of usage, extensive use of protection, development, extensive use, improvement, and development were determined.
Evaluation of the efficiency of functioning of the nature reserve fund in the Pripet river basin in the Volyn region
Authors: Nekos Alla , Boiaryn Mariia , Karpyuk Zoya , Kotsun Larisa , Andreyeva Valentina , Lugowska Maria
Published: September 2024

Introduction. Considerable attention of scientists at the current stage of development of society is given to the theory of formation and assessment of the state of the nature reserve network and its ability to ensure biodiversity. The upper part of the Pripet River basin in the Volyn region is marked by various nature-reserved objects that belong to the pan-European, national and regional eco-networks.

The objective of the work is the assessment and territorial distribution of NRF within the Pripet River basin in Volyn.

Methods. The research used a complex and systematic approach, as well as mathematical, cartographic and comparative descriptive methods.

Results. The river basin contains 314 objects of the nature reserve fund (NRF) with a total area of 164,735.7 hectares. The actual area is 149,186.4 hectares as a number of objects that are included in the total area of the nature reserve fund are actually located within the boundaries of other NRF objects, much larger in area. There are more than 40 such objects in the Pripet river basin. Such objects located within several river basins are also found within the basins of the main tributaries of the Pripet – the Vyzhivka, the Turia, the Tsyr, the Stokhid, the Styr rivers. In the upper Pripet River basin, there is an uneven distribution of protected areas across the territory, which indicates the need to increase their size in the Styr, Turia, Vyzhivka, and Korostyanka river basins to achieve an optimal ratio of areas and conserve species biodiversity based on a basin approach. The results of the calculation of the insularity index of the NRF of the Volyn region and of the degree of protection within the river basins are presented. The effectiveness of the nature reserve fund of the Pripet River basin was assessed, where the actual area of the protected area is 149,186.4 ha, the density of objects is 2.14 per 100 km2, the degree of protection (Spro) is 10.17%, and the insularity index (I) is 0.32. Twelve species of flora included in the International Red Lists were identified (Daphne cneorum L., Cypripedium calceolus L., Aldrovanda vesiculosa L., Salvinia natans (L.) All., Jurinea cyanoides (L.) Rchb., Tragopogon ucrainicus Artemczuk., Silene lithuanica Zapal., Liparis loeselii (L.) Rich., Pulsatilla patens (L.) Mill., Saxifraga hirculus L., Galanthus nivalis L., Crataegus ucrainica Pojark.), the areas of distribution of which are protected areas located in the Pripet River basin.

Conclusions. Prospectively, a successful expansion of the NRF area of the basin will make it possible to develop a national and pan-European eco-network, as well as to expand the area of wetlands of international importance.
Exploring the Pivotal Association of AI in Cancer Stem Cells Detection and Treatment
Authors: Abubakar Muhammad
Published: September 2024

Cancer stem cells (CSCs), or tumor-initiating cells (TICs), are cancerous cell subpopulations that remain while tumor cells propagate as a unique subset and exhibit multiple applications in several diseases. They are responsible for cancer cell initiation, development, metastasis, proliferation, and recurrence due to their self-renewal and differentiation abilities in many kinds of cells. Artificial intelligence (AI) has gained significant attention because of its vast applications in various fields including agriculture, healthcare, transportation, and robotics, particularly in detecting human diseases such as cancer. The division and metastasis of cancerous cells are not easy to identify at early stages due to their uncontrolled situations. It has provided some real-time pictures of cancer progression and relapse. The purpose of this review paper is to explore new investigations into the role of AI in cancer stem cell progression and metastasis and in regenerative medicines. It describes the association of machine learning and AI with CSCs along with its numerous applications from cancer diagnosis to therapy. This review has also provided key challenges and future directions of AI in cancer stem cell research diagnosis and therapeutic approach.
ATM is a Prognostic Biomarker of Survival in Head and Neck Squamous Cell Carcinoma Patients
Authors: Abid Muhammad Umair
Published: September 2024

This review examines the role of ATM expression in head and neck squamous cell carcinoma (HNSCC). Analysis revealed significant overexpression of ATM in HNSCC cells compared to normal control samples, suggesting its involvement in cancer proliferation. ATM expression was notably upregulated across various clinical parameters, including different stages of cancer, racial groups, genders, and age groups, highlighting its role in cancer progression. Validation using the GEPIA2 tool confirmed strong ATM expression throughout all four stages of HNSCC, with the highest levels in stage II and the lowest in stage I. Promoter methylation analysis of ATM showed distinct patterns across different demographics and cancer stages, reinforcing its significance. The study also explored the relationship between ATM expression and patient outcomes using the KM plotter tool, finding that high ATM expression was associated with better overall survival (OS), while low ATM expression correlated with better disease-free survival (DFS). Genetic mutation analysis via cBioPortal identified minimal ATM mutations in HNSCC, including in-frame, splice, truncating, and missense mutations, suggesting their role in ATM dysregulation. The STRING tool was used to construct a protein-protein interaction (PPI) network, revealing that the ATM gene interacts with ten key genes (NBN, ATR, CHEK2, MDC1, MSH2, MSH6, MRE11, TP53, TP53BP1, BRCA1), indicating its involvement in various biological functions. Functional annotation of differentially expressed genes (DEGs) through the DAVID web server revealed their participation in critical biological processes, including double-strand break repair, cellular response to DNA damage, and DNA damage checkpoints. KEGG pathway analysis further linked DEGs to cellular senescence, platinum drug resistance, homologous recombination, p53 signaling, and the cell cycle, underscoring ATM’s multifaceted role in HNSCC.
Clinical Application Study of Super-Mini Percutaneous Nephrolithotomy in the Treatment of Kidney Stones
Authors: You Zehong , Lian Wenyong
Published: September 2024

Objective: To observe the clinical efficacy and complication rates of different stone fragmentation techniques in the treatment of kidney stones. Methods: This study selected 100 patients with urinary stones treated at the Third Division General Hospital from 2021 to November 2023 as subjects. The control group (n = 50) received conventional percutaneous nephrolithotomy (PCNL) for stone fragmentation, while the research group (n = 50) received super-mini percutaneous nephrolithotomy (SMP) treatment. Surgical parameters, stone clearance rates, recurrence rates, and complication rates were compared between the two groups. Results: After treatment, the surgical parameters in the research group were significantly better than those in the control group. The research group had a higher stone clearance rate and lower rates of stone recurrence and complications (P < 0.05). Conclusion: Compared with conventional PCNL, SMP shows better clinical outcomes for patients with kidney stones. It improves surgical parameters, increases stone clearance rates, and reduces both stone recurrence and complication rates, making it a valuable technique for clinical reference.
Clinical Analysis of Acupuncture Combined with Acupoint Injection for the Treatment of Chronic Nonbacterial Prostatitis
Authors: Sun Xizhe , Yu Xiwen , Fan Chen , Chen Meixun , Dao Na , Hao Chengxin , Wu Jiamei
Published: September 2024

Objective: To evaluate the therapeutic effect of acupuncture combined with acupoint injection on chronic nonbacterial prostatitis (CNP). Methods: A total of 72 CNP patients admitted between March 2022 and October 2023 were selected. The patients were randomly divided into two groups using a random number table. The combined treatment group (36 cases) received acupuncture combined with acupoint injection therapy, while the control group (36 cases) received conventional Western medicine treatment. The overall efficacy rate, symptom severity, prostatic fluid indicators, incidence of adverse reactions, and recurrence rates were compared. Results: The overall efficacy rate of the combined treatment group was higher than that of the control group (P < 0.05). After 10 days of treatment, the symptom severity score of the combined treatment group was higher than that of the control group, and the prostatic fluid indicators were lower than those of the control group (P < 0.05). The incidence of adverse reactions in the combined treatment group was lower than in the control group (P < 0.05). During the follow-up period of 1–6 months, the recurrence rate in the combined treatment group was lower than that in the control group (P < 0.05). Conclusion: Acupuncture combined with acupoint injection can alleviate CNP disease symptoms, improve prostate function, and prevent post-treatment adverse reactions. It also has a lower recurrence risk and demonstrates excellent efficacy.
Síndrome metabólico: una mirada a los factores de riesgo y su abordaje integral
Authors: García Delgado Hillary Raquel , Vintimilla Martínez José David , Vera Jara Carlos Alejandro , Jiménez Barcia Walter Eduardo
Published: September 2024

El síndrome metabólico es un conjunto de factores de riesgo que, al presentarse juntos, aumentan significativamente el riesgo de desarrollar enfermedades cardiovasculares, diabetes tipo 2 y otras complicaciones crónicas. Para llevar a cabo esta revisión, se realizó una búsqueda exhaustiva en las bases de datos científicas PubMed, Scopus y Cochrane Library, utilizando los términos "síndrome metabólico", "factores de riesgo", "abordaje integral" y sus sinónimos en español e inglés. Se incluyeron estudios originales publicados en revistas indexadas desde el año 2010 hasta la fecha de la búsqueda. Los datos extraídos fueron analizados de manera cualitativa para identificar temas recurrentes y tendencias en la literatura. La obesidad abdominal se erige como el principal factor de riesgo, pero otros como la resistencia a la insulina, la dislipidemia y la hipertensión arterial también juegan un papel crucial. La etiología del síndrome metabólico es multifactorial, involucrando tanto factores genéticos como ambientales. El abordaje terapéutico debe ser integral y personalizado, combinando cambios en el estilo de vida, como la adopción de una dieta saludable y la práctica regular de ejercicio físico, con el uso de fármacos cuando sea necesario.
Factors of winter moisture movement in arable soils of the Ishim steppe
Authors: Kravtsov Yu. V.
Published: September 2024

Based on the materials of long-term field observations in the southern regions of the Omsk region, the influence of the main factors on the winter movement of moisture in arable soils of the Ishim steppe was traced. The penetration depth of 0 °С determines the lower boundary and vertical thickness of the moisture freezing layer. The distance between its lower edge and the penetration depth of 0 °С is 20–40 cm. The penetration depth of 0 °С is predetermined by the air temperature and the thickness of the snow cover and reaches 170–240 cm. The forms of moisture dominant in the soil are associated with the granulometric composition. Film moisture prevails in the heavy loamy, highly silty soil-ground strata of the Ishim steppe. The content of capillary-backed and free gravitational water does not exceed 6% of the soil volume at full moisture capacity, which determines the small volume of moisture freezing (up to 50 mm). Thermogradient migration of moisture is determined by field methods in highly moistened soil-ground strata. High humidity of the soils and rocks of the Ishim steppe is associated with their granulometric composition and the close occurrence of groundwater. If in the second ten days of October groundwater is recorded at a depth of less than 3 m, the layer of moisture freezing at the end of March is noted in the depth range between 40–80 and 160–200 cm, the volume of cryogenic accumulation is 30–50 mm, including in the upper meter layer – 10–25 mm. If groundwater is detected at a depth of more than 3 m in the autumn, the freezing layer is fixed at 80 to 160–200 cm, the moisture gain in it is 15–30 mm, in the 0–100 cm layer the moisture content does not change. The role of cryogenic accumulation in replenishing the post-vegetation moisture deficit in the root layer of spring grains is modest. This process is significant for the formation of conditions for anaerobiosis and the development of modern hydromorphism in the lower soil horizons and in the subsoil strata.
Chlorophyll fluorescence in the leaves of wheat seedlings under the combined effect of chloride salinity and infection with Bipolaris sorokiniana
Authors: Gurova T. A. , Chesnochenko N. E.
Published: September 2024

The results of the studies of photosynthetic activity of the seedlings of spring soft wheat three varieties and their adaptive responses to the combined effect of infection with the pathogen of common root rot of cereals Bipolaris sorokiniana Shoem. (B. sorokiniana) and chloride salinization on the parameters of chlorophyll fluorescence (ChlF) are presented. The seedlings were grown from pathogen-infected 3-day-old germinated seeds on sodium chloride solution (experiment) and on tap water (control) under specified climatic conditions. ChlF was recorded in 10, 12, 14, and 16-day-old seedlings using a Dual-PAM-100/F fluorimeter in a Slow Kinetics mode. The studies were carried out in 2022, 2023. The informativeness of the ChlF parameters Y(II), ETR, qP, Y(NPQ), qN and Y(NO) as biomarkers of photosynthetic activity and assessment of the resistance of the varieties to the combined effects of B. sorokiniana and chloride salinity was confirmed. The Fv /F0 and Fv /Fm parameters turned out to be less sensitive. The maximum significant intervarietal differences (from 1.8 to 4.3 times) were detected in six parameters of the ChlF. The smallest changes in ChlF parameters relative to the control were found in the more resistant variety Sibirskaya 21 compared to the less resistant varieties Novosibirskaya 41 and Novosibirskaya 29. Severe stress condition on the 16th day of cultivation of the Novosibirskaya 29 and Novosibirskaya 41 seedlings resulted in a synchronous increase in the parameter of unregulated non-photochemical quenching of ChlF Y(NO) by 45.8 and 59.9% and a decrease in the parameters of the regulated photochemical quenching Y(NPQ) and qN from 44.5 to 58.9%, respectively. This indicates a decrease in the efficiency of protective regulatory mechanisms during photosynthesis, which can serve as a diagnostic indicator in assessing the stress tolerance of varieties. It is concluded that it is possible to use ChlF parameters to assess photosynthetic activity, identify adaptive components and phenotyping of wheat varieties for resistance under the combined action of B. sorokiniana and chloride salinity.
Fiber flax varieties of domestic selection under conditions of the Tomsk region
Authors: Popova G. A. , Polyakova O. I. , Rogalskaya N. B. , Trofimova V. M. , Shuleiko A. A.
Published: September 2024

The results of the study of 20 samples of cultivated flax (Linum usitatissimum L.) of the Federal Scientific Center of Bast Crops in 2021–2023 are presented. The field studies were conducted in the sub-taiga zone of the Tomsk region. Natural and climatic conditions corresponded to the requirements of fiber flax cultivation. As a result of the conducted research, valuable and flexible source material for the creation of varieties with high productivity traits has been identified. The varieties of the Pskov selection – Antey, Voskhod, Nord, Chance, Tver (Torzhok) selection – Polet, Universal, Smolensk selection – Phoenix, Impulse and standard Pamyati Krepkova – stood out in terms of total and technical length of the stems. The total stem length reached 90 cm and above, the technical stem length was more than 80 cm. The leaders in terms of fiber content in the technical part of the stems were varieties of the Tver selection (Torzhok): Tonus, Visit, Pskov varieties – Kvartet, Orion, Peresvet – 40% and higher. The highest value for the characteristic of stem slenderness (the ratio between technical length and stem thickness) was observed in the varieties Voskhod (681.0) and Peresvet (652.6). In terms of linear stem density, the varieties differed insignificantly among themselves, with most varieties having values in the range of 5.0–6.0 mg/cm. The influence of the factor " The year of inclusion in the State Register of BA of the Russian Federation" was also studied. The factor had the greatest influence on the fiber content trait. Varieties with earlier dates of inclusion in the State Register showed low fiber yield. Russian flax varieties are recognized as promising and are included in the breeding process as male and female seed parents during hybridization.
Distribution of Robinia pseudoacacia pests in the south of the Russian Far East
Authors: Kolyada N. A.
Published: September 2024

In recent years, one of the problems associated with introduced woody plant species has been the invasion of pests and diseases into their secondary habitats. Such an invader in Russia, including the Far East, is Robinia pseudoacacia L. In order to assess the distribution of pests of this species in the south of the Far East and to evaluate the damage caused by them, monitoring of plantations in populated areas of the region is necessary. The article provides data on the distribution of pests R. pseudoacacia – Euura tibialis (Newmann, 1837) (Hymenoptera: Tenthredinidae), Obolodiplosis robiniae (Hald.,1847) (Diptera: Cecidomyiidae) in the Primorsky Territory. Studies of the R. pseudoacacia plantings show that E. tibialis occurs in 9 of 24 localities. On each plant specimen, approximately 2–3%, in some cases up to 4%, of the leaf plates were damaged to a greater or lesser extent. The northernmost point of the pest distribution is the town of Luchegorsk, the southern point is the Slavyanka settlement. The most affected are the city of Ussuriysk and the village Sinij Gay. A pest such as O. robiniae is found in all the 24 surveyed settlements. The northernmost point of its distribution is the city of Luchegorsk, the southernmost point is the Hassan settlement. The most affected by this pest is the town of Artem, the town of Bolshoi Kamen, Khorol settlement, Tavrichanka village. Further monitoring of R. pseudoacacia plantations in the Primorsky Territory is necessary in order to determine the distribution of its pests and assess the damage they cause.
КОМПЛЕКСЫ НИКЕЛЯ(II) НА ОСНОВЕ ПИРИДИЛ- И ХИНОЛИЛ-СОДЕРЖАЩИХ ДИАЛКИЛФОСФИНОКСИДОВ
Authors: Еникеева К.Р. , Литвинов И.А. , Любина А.П. , Волошина А.Д. , Мусина Э.И. , Карасик А.А.
Published: September 2024

На основе 1,5-N,O-лигандов – диизопропил(пиридин-2-илметил)фосфиноксида L1 и диизопропил(хинолин-2-илметил)фосфиноксида L2 получены бис-хелатные комплексы никеля(II) [Ni(L1)2(H2O)2](BF4)2 (1-H2O), и [Ni(L2)2](BF4)2 (2). Структура и состав комплексов 1-H2O и 2 подтверждены методами масс- и ИК-спектроскопии, термогравиметрического и элементного анализа. В растворах комплексы 1-H2O и 2 претерпевают диссоциацию, сопровождающуюся в случае комплекса 1-H2O заменой аква-лигандов на ацетонитрил с образованием комплекса [Ni(L1)2(CH3CN)2](BF4)2 (1-СH3CN), а в случае 2 – заменой фосфиноксидных лигандов на шесть молекул воды с образованием водородно-связанного агломерата гексаакваникеля(II) [Ni2(L2)4(H2O)12](BF4)2 (3). Структура комплексов 1-H2O, 1-СH3CN и 3 в кристаллах установлена с помощью рентгеноструктурного анализа. Для синтезированных в данной работе комплексов никеля(II) изучены цитотоксические свойства по отношению к раковым клеткам M-HeLa, HuTu80 и нормальным клеточным линиям Chang Liver.
Crystallographic Feature, Synthon Investigation and Hirshfeld Surface Analysis of Two 3D Supramolecular Salts of Pyridine and Organic Carboxylic Acids Constructed by Classical H-Bonds and Some Noncovalent Interactions
Authors: Ma X.-D. , Yang Y. , Zhou J.-X. , Li Z.-Z. , Hong X. , Jin S.-W. , Wang D.-Q.
Published: September 2024

The preparation, X-ray crystal structure, Fourier Transform infrared (FTIR) spectroscopy, and elemental analysis of the complexes 1-2 from the pyridine and the mono- and dicarboxylic acids are reported. XRD and FTIR analysis demonstrated that both belong to the organic salt. The salt 1 crystallizes in the triclinic, space group Pī, with a = 7.271(3) Å, b = 9.548(4) Å, c = 14.698(7) Å, α = 78.435(6)°, β = 85.975(7)°, γ = 71.492(6)°，V = 948.0(8) Å3, Z = 2. The salt 2 crystallizes in the orthorhombic, space group P212121, with a = 7.9476(6) Å, b = 11.6756(9) Å, c = 25.686(2) Å, α = β = γ = 90°, V = 2383.4(3) Å3, Z = 4. In this study, the pyridine at 1-2 were both involved in the classical ionic N-H∙∙∙O H-bonds. The O-H···O H-bonds were also present in the both salts. Apart from the classical H-bonds, the auxiliary interactions of CH···O, CH3-O, CH3-CH3, CH-π, and O-π also helped the stabilization and expansion of the whole high-dimensional (3D) packings. Analysis by the Hirshfeld surface provides additional views into the prevalence of the various short contacts in the crystal structure. On account of the subtle balance of the various nonbonding associations the synthons R22(7), R22(10), R32(8), R32(10), R33(9), R33(19), R43(15), R44(17), R54(12) and R64(18) were noted at the salts. For the combination of the classical H-bonds plus the various non-covalent contacts, the salts adopted the 3D net. In conclusion, we have shown that 3D structures can be constructed by the collective non-covalent interactions.
Eriyik Yığma Modelleme ile Farklı Yazdırma Parametrelerinde Üretilen Yapıların Titreşim Sönümleme Özelliklerinin Torna Tezgâhı Üzerinde Deneysel Araştırılması
Authors: Sevim Çağlar , Parlak Mehmet
Published: September 2024

Eriyik yığma modelleme teknolojisinin gelişimi ile istenilen özelliklerde tasarımı yapılan malzemelerin ve yapıların üretilmesi mümkün hale gelmiştir. Özellikle yazdırma açısı, doluluk oranı ve içyapı gibi yapısal yazdırma parametrelerinin, üretilen yapının mekanik özellikleri üzerinde son derece etkili olduğu yapılan çalışmalarda ortaya konulmuştur. Bu çalışmada ise, farklı doluluk oranı ve içyapılarda üretilen yapıların titreşim sönümleme özellikleri, bir torna tezgâhı üzerinde deneysel olarak incelenmiştir. Deneyler sonucunda, içyapı ve doluluk oranının yapının sönümleme özelliği üzerinde etkili olduğu saptanmış ve bu sayede farklı yazdırma parametreleriyle uygulamaya özel ve istenilen sönüm özelliğini gösterebilecek izolatörlerin tasarlanabileceği ortaya konulmuştur.
Upaya Pemecahan Masalah Diabetes Melitus Tipe 2 pada Pasien Laki-Laki Usia 64 Tahun di Puskesmas Kuta Makmur Kabupaten Aceh Utara
Authors: Wahyuni Hendra , Mustafavi Farida
Published: September 2024

Diabetes Melitus merupakan masalah kesehatan global yang insidennya semakin meningkat. Sebanyak 346 juta orang di dunia menderita diabetes, dan diperkirakan mencapai 380 juta jiwa pada tahun 2025. Diabetes Melitus (DM) merupakan penyakit kronis yang ditandai dengan hiperglikemia dan intoleransi glukosa yang terjadi karena kelenjar pankreas tidak dapat memproduksi insulin secara adekuat yang atau karena tubuh tidak dapat menggunakan insulin yang diproduksi secara efektif atau kedua-duanya. Penatalaksanaan Diabetes Melitus terdiri dari 5 pilar yaitu edukasi, diet, latihan fisik, kepatuhan obat, selain itu juga termasuk pencegahan Diabetes Melitus dengan pemantauan kadar gula darah.
Studi Kasus Sepsis pada Stroke Hemoragik
Authors: Roskaraulya Chaira Khuntum , Maulina Meutia
Published: September 2024

Stroke merupakan penyakit gangguan fungsional otak berupa kelumpuhan pada saraf (defisit neurologis) akibat gangguan aliran darah pada salah satu bagian otak. Data di Indonesia memperlihatkan stroke sebagai penyebab Kematian terbanyak ketiga dengan angka kematian sebanyak 138.268 jiwa atau 9,7% dari total kematian. Penyakit stroke dibagi menjadi dua macam yaitu stroke iskemik dan stroke hemoragik. Stroke hemoragik terjadi akibat pecahnya pembuluh darah di otak. Kondisi tersebut menimbulkan gejala neurologis yang terjadi secara tiba-tiba dan seringkali diikuti gejala akibat efek desak ruang atau peningkatan tekanan intrakranial (TIK). Terdapat risiko tinggi terjadinya sepsis dengan kejadian stroke hemoragik akibat disregulasi respon imun. Hipertensi tak terkontrol merupakan faktor risiko ytang mendominasi pada stroke hemoragik. Penegakan diagnosis memerlukan pemeriksaan Computed Tomography Scan (CT-Scan) yang menjadi gold-standar. Pemeriksaan laboratorium juga perlu untuk memperbaiki faktor risiko yang ada pada pasien. Tindakan  medis  pada  stroke  hemoragik  ditujukan  agar  penderita  tetap hidup   dengan   harapan   perdarahan   dapat   berhenti  secara   spontan.Tindakan medis yang dilakukan pada penderita stroke hemoragik meliputi: tindakan operatif, tindakan konservatif, dan pengendalian peningkatan TIK. Metode yang digunakan adalah menggunakan studi kasus. Studi kasus ini membahas Tn. I 59 tahun dengan stroke hemoragik dengan faktor risiko gaya hidup yang tidak sehat yaitu, merokok dan pola makan yang berlemak dan kolesterol tinggi, serta hipertensi dengan melakukan anamnesa, pemeriksaan fisik, dan penunjang serta melakukan penatalaksanaan dan edukasi yang mungkin diterapkan pada pasien di masa mendatang.
MALL in a challenging EFL context: Can it really enhance L2 vocabulary learning?
Authors: Alrickaby Amjed
Published: September 2024

This study seeks to extend the application MALL to a challenging EFL context—Iraq—examining its effectiveness in enhancing vocabulary learning in EFL classes. These classes are characterized by overcrowded and poorly equipped facilities, students motivated primarily by exam scores, and teaching is textbook-centred and examination-oriented. It employs a mixed methods approach to evaluate the effectiveness of a self-developed application designed to enhance vocabulary learning through vocabulary learning enhancement principles (involvement, spacing, multimedia, and gamification). Over a five-week period, 131 secondary school students (aged 15-16) from two schools in Iraq participated. Within each school, students were randomly assigned to either a control group or a treatment group. However, the implementation of the experiment varied between the two schools. In the first school (S1), students were incentivized to complete tasks on the application, with progress monitored for rewards. In the second school (S2), students were only encouraged to complete the tasks without additional incentives. Statistical analysis revealed that students in the treatment group at S1 performed better than their peers in the control group. However, they were only able to retain 19 out of the 54 target vocabulary items whereas control group retained 4. In S2, no significant difference was observed between the treatment and control groups with each retaining 5 items. Follow-up interviews with teachers revealed that while the material was gamified and interactive, students still required a reward system to remain motivated. Despite this, MALL proved beneficial for teachers by enabling them to provide feedback to overcrowded classes and offering multimedia resources.
Problems and Solution Suggestions for Directors in Short Film Festivals in Türkiye
Authors: ÇÖM Şenol
Published: September 2024

Türkiye'de düzenlenen film festivalleri ile ilgili yapılacak bir çalışmada karşılaşılabilecek başlıca sorunlar arasında, başvurulacak kaynakların kısıtlılığı ve kurumsallaşma eksikliği bulunmaktadır. Türkiye'de "kısa film festivali"
başlığı altında düzenlenen etkinliklerin resmî web sayfalarında, güncel veya geçmiş yıllara ait başvuru yapan film sayısı, ön elemeyi geçen ve ödül alan filmlerin listesi gibi temel düzeydeki verilere dahi ulaşılamaması, bu festivallerin
kurumsallıktan ne kadar uzak olduğunun bir göstergesidir. Festivallerin bu durumu göz önüne alındığında, film üreticileri tarafında da durumun farklı olmadığı görülmektedir. Kısa film üreticileri, ticari bir dolaşımın olmaması
nedeniyle meslek örgütü oluşturma, dernekleşme gibi kurumsallaşma ve birlikte hareket etme konusunda ciddi sorunlarla karşı karşıyadır. Film üreticileri tarafında yaşanan kurumsallaşma sorununun temelinde, kısa film yönetmenlerinin
genellikle üniversitelerin ilgili bölümlerinde eğitim alan öğrenciler olması ve kısa film üretiminin lisans eğitimi sonrasında sürdürülebilir olmaması yatmaktadır. Türkiye'de düzenlenen film festivallerindeki sorunları ortaya koymak
ve çözüm önerileri sunmak amacıyla yapılan çalışmada, 2015, 2016 ve 2020 yılları arasında birden fazla film üreten, ulusal ve uluslararası film festivallerinde ödül almış kısa film yönetmenleri ile yüz yüze, görüntülü kayıt, telefonla
ses kaydı ve elektronik posta yöntemleri kullanılarak derinlemesine mülakatlar gerçekleştirilmiştir. Çalışmanın uygulama kısmı, yapılandırılmış görüşme tekniği ile yapılan derinlemesine yüz yüze görüşmelere dayanan nitel araştırmayı
kapsamaktadır. Yapılan analizler sonucunda, festivallerin kurumsallaşma ve kimlik kazanma noktasında yetersiz kaldığı ve bu durumun birçok sorunun temelinde yattığı belirlenmiştir. Çalışma, festivallerin yazılı ve görsel arşivlerini
düzenleyerek online erişime açmalarının ve böylece bilimsel araştırmalar için bir veri tabanı oluşturulmasının gerekliliğine vurgu yapmaktadır.
Determining The Opinions of Primary School Mathematics Teachers about Common Exams
Authors: BAKIRCI Hasan , KOÇAK Bedran , GEÇER Ayşe KESKİN
Published: September 2024

Bu çalışma, ilköğretim matematik öğretmenlerinin ortak sınav uygulaması hakkındaki düşüncelerini incelemeyi amaçlamaktadır. Çalışma, nitel araştırma desenlerinden olgu bilim deseni ile gerçekleştirilmiştir. Araştırmanın katılımcıları,
2023-2024 eğitim öğretim yılında Van ilinde görev yapan on iki matematik öğretmeninden oluşmaktadır. Çalışmaya katılan öğretmenler devlet okullarında görev yapmaktadır. Katılımcılar, amaçlı örneklem yöntemlerinden kolay ulaşılabilir
örneklemeye göre seçilmiştir. Araştırmanın verileri, altı sorudan oluşan yarı yapılandırılmış görüşme formuyla toplanmış ve elde edilen veriler içerik analizi yöntemiyle çözümlenmiştir. Öğretmenler, ortak sınav uygulamasının bazı
olumlu sonuçlarının yanı sıra sınırlılıklarını da belirtmişlerdir. Öğretmenler sınavın olumlu yönlerini; herkese aynı soruların sorulması, eşit ölçme yapması, soruların zorluk düzeylerinin farklı olması, öğrenciler arası eşit rekabet
sağlaması, öğrenci başarısını objektif bir şekilde değerlendirme şeklinde ifade etmişlerdir. Buna karşın öğretmenler ortak sınavların sınırlılıklarını ise, yerel ihtiyaçların göz ardı edilmesi, öğrenci motivasyonu üzerinde olumsuz
etki, eğitimdeki fırsat eşitsizliklerini derinleştirmesi ve sınav kaygısı olarak belirtmişlerdir. Bu sınırlılıklar, sınavın adil olamayacağını şeklinde yorumlamışlardır. Bu sonuçlardan hareketle, Milli Eğitim Bakanlığı'nın eğitim-öğretim
politikaları ve kararları alırken daha fazla öğretmen görüşü alması, bu tür uygulamaların daha katılımcı ve kapsayıcı olmasını sağlayabilir.
DIFFERENCES IN CAREER COMMITMENT AND CAREER SATISFACTION BETWEEN SHIFT AND TYPICAL WORK IN ORGANIZATIONS
Authors: ÖZTÜRK Uygar
Published: September 2024

The responsibility of career management is gradually shifting from organizations to individuals every day. With this transition, what employees think about their careers within the framework of individual career planning becomes increasingly
important. The employment structure is also transforming in parallel with career management. Particularly in the service sector, businesses employ staff on shifts to achieve their goals more efficiently. Understanding the career
perceptions of shift workers, a growing segment of the workforce has become more critical. The research stands out from other studies by analyzing a sample group that has worked in both types of employment (typical and shift).
Within this scope, the study aims to understand whether shift work impacts career commitment and career satisfaction. In this context, the study's sample group consists of individuals who have previously worked on shifts and later
as typical employees. The research was conducted using quantitative research methods with a survey approach. Paired sample t-tests and correlation analysis were performed to test the study's hypotheses. The study results indicate
that the levels of career commitment and career satisfaction are significantly higher in typical employment compared to shift work.