bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPLEMENTASI PENGGUNAAN MEDIA DIGITAL BAGI PERTUMBUHAN JEMAAT BERDASARKAN 1 KORINTUS 9:20-21 DAN IMPIKASINYA BAGI JEMAAT GEREJA PANTEKOSTA ISA ALMASIH HOFALO MALANG
Authors: Halawa Estin Lorenza , Telaumbanua Sozanolo
Published: April 2022

Survey on the use of digital media for congregational growth at the Pentecostal Church of Isa Almasih Hofalo Malang. From the results of the discussion, it was found that digital media can be used as a medium for preaching (the gospel), as well as helping the growth of the congregation in terms of recognizing the truth of God's word. And this digital media is very influential for the growth of the congregation, precisely at the Isa Almasih Hofalo Pentecostal Church, Malang. This is done with the aim of knowing how the influence of digital media for the growth of the congregation at the Pentecostal Church of Isa Almasih Hofalo Malang, so that the use of media can have an impact and bring blessings in their introduction to the truth of God's word. The research method used in writing this thesis is to use quantitative methods. And to carry out the research method, the things that will be done are: first, data collection and collection through journals and books related to the titles discussed in this thesis. Second, by distributing a questionnaire (questionnaire) to the congregation of the Pentecostal Church of Isa Almasih Malang. The total population used is 32 respondents. Before the question instrument is used, to obtain good data, validity testing and reliability testing are first carried out. The data analysis technique used is descriptive data, normality test and simple linear regression test. Based on the results of research and calculations carried out using the SPSS 16.0 program as shown in the Coeffients table, the variable using digital media has a significance value of 0.000. The results in this study obtained a significance value of 0.000 < 0.05, it can be concluded that the hypothesis which reads "there is an effect of using digital media for the growth of the Isa Almasih Hofalo Pentecostal Church congregation in Malang" is accepted.
Boredom, Fragmentation, and the US Army in Eastern Europe
Authors: Hajjar Remi , Ender Morten
Published: April 2022

This article examines a forward-deployed US Army unit in Eastern Europe. Drawing from military sociology, the theoretical framework used to study this unit focused primarily on factors of boredom and the fragmentation model of organizational culture. The methodological approach was mixed, including interviews and participant and non-participant observations of the deployed soldiers and military civilians. The research explored unit members’ perceptions about unit leadership, quality of life, communication with loved ones, the mission, work roles, interactions with the local foreign military and civilians, and unit diversity. The findings contribute to a nuanced understanding of the relationship between military boredom and fragmentation. Overall, we found some ambiguity regarding some parts of soldiers’ lives—including an unclear understanding regarding the nature of the mission. The study also found low to moderate levels of boredom across five domains: underutilization, cultural deprivation, lack of privacy, isolation, and time and space reorientation. Although in most cases the level of boredom related to perceived ambiguity (less boredom usually meant less perceived ambiguity), in some cases an inverse relationship was identified. We conclude that future studies should determine whether our findings apply to newer forward-deployed contexts in Eastern Europe and elsewhere.
Telecollaboration as a Tool to Enhance Critical Pedagogy in Spanish Heritage Language Instruction
Authors: Villa Laura , Barros García María Jesús
Published: April 2022

Abstract: This paper describes and evaluates our experience implementing telecollaboration in Spanish Heritage Language instruction in order to develop students’ critical reflection on issues that affect Latinx communities in the United States. Data and students’ samples collected in four SHL courses taught at Queens College-CUNY, New York City and Saint Xavier University, Chicago are presented and analyzed. We begin by explaining the motivation for the use of telecollaboration, and then outline the three modules of this project in relation to our goals: (1) to develop students’ understanding of the discursive and sociopolitical nature of language and identity; (2) to engage students in a discussion of the historic presence of Latinxs in the country and the patterns of Latinx migration to the US in the 20th and 21st centuries; and (3) to promote a critical reflection on the current living and working conditions of Latinx communities in New York and Chicago. We conclude with a general assessment of the project based on students’ work and our own reflections.
Virtopsy: A New Era in Forensic Medico-Legal Autopsies
Authors: Ahuja Pooja , Ansari Niha
Published: April 2022

In the field of forensic science, autopsy that is postmortem examination involves a thorough corpse examination done in order to determine the cause and manner of the death by invasive method. With the advancement of technology a new term: “Virtopsy” meaning virtual autopsy employs the application of imaging techniques namely computed tomography (CT) and magnetic resonance imaging (MRI) has proven its advantages in the forensic field. It involves the scanning of dead bodies in a non-invasive manner. It a great alternative to the traditional autopsy as it provides wide-range and systemic examination of the whole body in a less time duration, benefits in diagnosis as well as renders respect to religious sentiments. Method is more specific, sensitive, & precise and accurately reflect soft tissue injuries, organ damage, wound extent, fractures which provides instinctive and powerful court evidence for forensic identification. The chapter will be describing the importance of “Virtopsy” in the field of forensic science and its future scope in forensic crime investigations.
Medicinal Mushroom of Potential Pharmaceutical Toxic Importance: Contribution in Phytotherapy
Authors: Tembe Fokunang Estella , Grace Annih Mbong , Edith Abongwa Lem , Evelyn Bih Manju , Mayoudom Vanessa Tchadji , John Fomnboh Dobgima , Fokunang Charles
Published: April 2022

Orthodox medical practice depends greatly on the use of high throughput (HTP) pure pharmaceutical new chemical entities, with a purity that can easily be evaluated and whose efficacy and toxicity can show a dose-dependent, clear structure-activity relationships (SAR). On the contrary, natural products contain mixtures of natural bioactive metabolites that have not undergone any chemical analyses and whose mechanism of action is not known. Medicinal mushrooms have been used throughout the history of mankind for the treatment of various diseases including cancer. Nowadays they have been intensively studied and generated research interest in an attempt to reveal the chemical nature and mechanisms of action of their bioactive molecules. Targeted treatment of diseases, non-harmful for healthy tissues, has become a major objective in recent times and metabolites of fungal origin provide a vast reservoir of potential new chemical entities. There are many examples of mushrooms common for use globally that demonstrate the complex nature of their pharmaceutical potential This review paper attempts to show that some aspects of fungotherapy of the disease have been well studied. We also give an insight into the role of mushroom metabolites for treatment of diseases types that are especially susceptible to the fungal treatments.
Pathogenicity, Toxin Production, Control and Detection of Bacillus cereus
Authors: Mohammadi Barakatullah , Gorkina Natasha , A. Smith Stephanie
Published: April 2022

Bacillus cereus is a toxin-producing, endospore-forming, facultative bacterium ubiquitous in the environment. It has been associated with numerous foodborne illness outbreaks and is found in a variety of foods including grains, produce and processed foods. When present in high numbers, B. cereus produces toxins leading to foodborne illness. Although disease is usually self-limiting and resolves with a short time, illness can result in complications. Moreover, B. cereus is resistant to many antimicrobials which can make treatment difficult in scenarios where more extensive treatment is required. Current control methods are limited, and detection of this pathogen in food is often difficult due to its genetic similarity to Bacillus anthracis and Bacillus thuringiensis. Given this, more research is required to identify better process controls to reduce contamination of food with this ubiquitous organism, and develop better methods for detection.
Anxiety, Depression, and Quality of Life in Caregivers of Children with Cleft Lip and Palate: A Systematic Review
Authors: Namdar Parastoo , Pourasghar Mehdi , Lal Alizadeh Farzaneh , Shiva Atena
Published: April 2022

Context: Cleft Lip and Palate (CL/P) is the most common craniofacial malformation in the oral cavity, with a prevalence of “1 to 2in 1,000 live births worldwide. Parents with CL/P children are more prone to experience emotional disorders, especially depression, and have higher child-related stress than the parents of normal children. Due to the effect of the mental status of parents on children, the assessment of the psychological aspects of this problem and its effects on the patients and their parents is critical. Evidence Acquisition: This systematic review was carried out to determine the quality of life (QoL) and emotional problems, including anxiety and depression, in the mothers of CL/P children. All the published studies were searched in three electronic databases, including MEDLINE, PubMed, and Web of Science, up to December 30, 2020, using the keywords "Orofacial Clefts” and “Cleft Lip and Palate” in combination with “Anxiety," "Stress," "Depression," and "Quality of Life” in addition to “Parents," "Mothers," "Fathers," and "Caregivers." Results: Finally, 29 articles met the eligibility criteria for this review. Due to the differences in health care and culture, controversial findings were obtained on the QoL of parents with CL/P children. Social support plays a vital role in the prevention, resolution, and treatment of psychological problems of parents with CL/P children. The majority of studies confirmed the higher levels of anxiety and depression in caregivers of children with CL/P than in normal individuals. Conclusions: These findings emphasize the necessity of psychological screening in the first few months following the diagnosis to facilitate providing appropriate psychological support for parents with CL/P children.
Examination of miners' immune response to coal dust and their quality of life
Authors: Mijović Biljana Mijović
Published: April 2022

Introduction. Inhalation of coal dust during blasting in brown coal mines has been shown to lead to a lung disease called pneumoconiosis. There is very little data in the literature on the direct impact of coal on the quality of life of people who work in coal mines as well as the body's immune response to the effects of coal dust. The aim was to examine the immune response to exposure to coal dust in miners in a brown coal mine and whether mine workers have poorer quality of life compared to those not exposed to coal dust. Methods. This is a cross-sectional study among 100 employees in the Brown Coal Mine in Ugljevik, of which 50 of them are exposed to coal dust on a daily basis. Blood samples were taken from all subjects to test for the presence of cytokines IL-2, 4, 5, 9, 10, 13, 17A, 17F, 21, 22, IFN-g and TNF-a. The quality of life of employees was measured using a questionnaire for self-assessment of physical and mental health (36-item Short-Form Health Survey, SF-36). Results. Group of miners had a significantly (p<0.05) higher concentrations of pro-inflammatory cytokines IL-6, IFN-g, IL-17A and IL-22 when compared to the control group. Subjects from the control group had significantly (p<0.05) higher concentrations of anti-inflammatory cytokines IL-4 and IL-10 when compared to the group of miners. The quality of life was significantly (p<0.05) better in the control group when compared to the group of miners. Conclusion. Physical functioning, general health, mental health and Physical component summary were significantly poorer in the group of miners. Exposition to coal dust led to a significant increase in the production of pro-inflammatory cytokines and a decrease in the production of anti-inflammatory cytokines.
The importance of physical activity in diabetes
Authors: Purković Miloš , Vukašinović Danka , Radak Una
Published: April 2022

Introduction. Obesity is becoming a global urgent issue that is considered a health problem in developed and developing countries. Obesity is a major risk factor for many non-communicable diseases such as cardiovascular diseases, type 2 diabetes mellitus (DM2), hypertension, coronary heart disease, or certain types of cancer. Physical activity is crucial for a healthy lifestyle. The aim of this study was to determine whether there is a difference in the physical activity of obese people with type 2 diabetes and obese people without type 2 diabetes. Methods. This cross-sectional study included 50 obese patients with type 2 diabetes and 57 obese patients without type 2 diabetes. All patients went through the questionnaire, anthropometric measurements and laboratory tests. Type 2 diabetes was diagnosed in accordance with the American Diabetes Association. Data on physical activity were collected using the IPAQ (International Physical Activity Questionnaire), which was composed of questions on various physical activities in the previous 7 days. Results. Activities at work and on the way to work in patients with type 2 diabetes were significantly lower compared to these activities in patients without type 2 diabetes (p <0.001). Also, leisure time physical activities were lower in people with DM2 (p = 0.001). Just in case of household chores, subjects with DM2 had more utilized metabolic equivalent (MET) minutes whose utilization rate was close to 1700 MET minutes compared to 1500 MET minutes in subjects without DM2. Conclusion. The results of this study indicate that obese subjects with DM2 are less active than obese subjects without DM2. Therefore, they should be recommended regular physical activities for at least 150 minutes per week to overcome the problem of obesity and the problem of DM2.
Moralni razvoj i moralno vaspitanje učenika u školi
Authors: Jelić Marija , Stojković Irena , Antonijević Radovan
Published: April 2022

An increasingly frequent criticism of the school system refers to the insufficient connection between pedagogical and educational processes, i.e., the fact that the pedagogical function of the school is neglected in everyday school practice. The pedagogical role of the school can be discussed in general or more specifically, given the extent to which the school can contribute to encouraging the moral development of students and the operationalization of the tasks of moral education. So far, empirical research on moral education in our schools has been small, which indicates that this area is insufficiently researched and does not respond to the modern-day needs of pedagogical practice, especially the area related to the structure of school activities. The aim of this paper is to point out the potential and effects of curricular and extracurricular activities on the moral development and moral education of pupils. Focusing on the discrepancy between normative and practical functioning of schools, the authors emphasize in the introductory part of the paper the importance of the pedagogical role of the school from the aspect of moral development and moral education. Based on the review of the previous theoretical and research findings in this field, the characteristics of moral development are indicated as well as their compliance with the goals of moral education and the forms of pedagogical activities in schools. In addition, by considering the structure of school activities and the role of various participants in the educational process in the operationalization of the pedagogical role of the school, and based on modern pedagogical and didactic standpoints, the opportunities offered by and the effects of the curricular and extracurricular activities on moral development and moral education of pupils are considered as well. The authors of the paper emphasize in the conclusion which preconditions have to be met to make school activities functional in terms of pupils' moral development and moral education.
Roditeljska samoprocena postupaka u vaspitnom radu s decom
Authors: Radovanović Ivica , Bogavac Dragana , Milosavljević-Đukić Tatjana
Published: April 2022

The goal of our research was to examine how parents evaluate their pedagogical actions regarding their children. The research was conducted on a sample of 198 parents of children attending final grades of primary school in Eastern Serbia (Negotin, Bor, Zaječar, Kladovo, and Knjaževac). Survey method and theoretical analysis method were used in the research. The researchers developed a fivelevel Likert type scale, the Parents' Self-Evaluation of Pedagogical Actions, consisting of 30 items referring to different pedagogical actions relative to affective dimensions and control dimensions. The results show the prevalence of affective dimension in parents' self-evaluation. When it comes to parents' level of education, the results indicate that parents with college and university degrees are more in the zone of responsible parenthood than parents who finished only primary school or have high-school diplomas. The results of this research can be a special challenge in terms of including children in some future research to examine the problem of parents' pedagogical actions from both perspectives. The research findings can also be used in the context of the development of educational programmes that can be implemented through cooperation between schools and parents.
Doprinos primene direktne u odnosu na indirektnu hands-on instrukciju na postignuća učenika u početnom obrazovanju u prirodnim naukama
Authors: Cvjetićanin Stanko , Maričić Mirjana
Published: April 2022

Ensuring the optimal (adequate) level of instructional guidance in teaching natural sciences in primary education is of utmost importance for the proper acquisition and application of knowledge. The goal of this paper is to examine the contribution of direct hands-on instruction relative to an indirect one on student achievement regarding the movement and properties of materials in classes of integrated natural sciences (classes of the World around Us and Science and Social Studies). The research tasks include a comparative analysis of the quality of students' knowledge acquired with the application of direct in relation to indirect hands-on instruction, as well as the analysis of the permanence of that knowledge. The following methods were used in the research: theoretical analysis method, descriptive-analytical method, and experimental method. The research technique is testing, and the instrument is knowledge tests (pre-test, post-test, and re-test). The research sample consisted of 94 students of the third grade of primary school, divided into two groups: E1 (application of indirect hands-on instruction) and E2 group (application of direct hands-on instruction). The results of the research indicate that the students of the E1 group achieved somewhat better and more lasting knowledge about the movement and properties of materials in relation to the students of the E2 group. However, a significant difference between their achievements was observed only at the cognitive level evaluated in the post-test. This leads to the conclusion that both types of hands-on instructions should be applied in the third grade when teaching the content related to the movement and properties of materials. In addition, greater preference should be given to indirect over direct hands-on instruction because it not only provides an opportunity for students to have better achievement, but also it enables a greater degree of independent research and experimental work.
Phonemic awareness as an indicator of preliteral abilities in Serbian speaking children with and without specific language impairment
Authors: Milošević Neda , Vuković Mile , Ristić Ivana
Published: April 2022

This study is based on theoretical and empirical understanding of phonemic awareness in Serbian speaking children with and without specific language impairment (SLI). The aim of this paper is to compare the phonemic awareness in children with SLI and children with typical language development (TLD) who are between 5.11 and 7 years of age. This study included 40 participants with SLI and 80 participants with TLD. The subtest for evaluation of phonemic awareness from The Test for Evaluating Reading and Writing Pre-Skills - PredČiP (Kuvač Kraljević & Lenček, 2012) was used. Statistically significant differences were confirmed on both tasks of phonemic awareness (p < .001). The half of children of the SLI group had borderline or poor achievement, generally lower than children with TLD. Bearing in mind that Serbian language has a regular orthography and clear morphological specificities, compared to most world languages, it is expected that Serbian-speaking children would master phonological awareness tasks more easily. Consequently, we believe that an early detection of phonological disorders is particularly important for the Serbian-speaking children. Having in mind that literature data indicate that children who, prior to starting school, are diagnosed with SLI, later encounter interference with reading and writing, we suggest the implementation of a specific preventive program for developing phonological skills, or training of phonemic awareness, in all children.
[entre]margens poéticas e pedagógicas
Authors:   Udesc, Schmidlin Elaine
Published: April 2022

O texto apresenta as relações (in)tensas entre o poético e o pedagógico, as quais foram experimentadas durante o processo de um curso de licenciatura, bem como pretende contribuir com a produção de uma diferença de sentido para a formação docente. A escrita, em forma de ensaio, propõe entrelaçamentos com a filosofia e a literatura e deriva de encontros ocorridos em disciplinas de estágios curriculares, em que estudantes foram provocados a pensar um trabalho poético a partir de projetos de ensino e relatórios que consistem de trabalhos pedagógicos obrigatórios para atuação em escolas. Com a finalidade de provocar uma diferença em modos de viver a vida e a docência, essas proposições, em formato de publicações artísticas, tinham o propósito de agir como dispositivos para esburacar a representação docente padrão, usualmente construída no processo de formação.
PELES PEDAGÓGICAS
Authors:   Mackenzie/SP, Martins Mirian Celeste
Published: April 2022

Ao apresentar o livro sensorial Peles Pedagógicas (2010) composto como um mostruário de tecidos este artigo se torna um modo de pensar sobre processos de criação e desvelar a vida de artista, de pesquisadora e de professora que nele se visibiliza. As “peles-metáforas” foram produzidas com matérias, texturas, cores, formas, palavras e porcentagens que, como tecido-metáfora, provocam outras leituras.
Nursing care of a patient with acute severe fatty pancreatitis complicated with severe pneumonia
Authors:   The Emergency and Disaster Medical Center, The Seventh Affiliated Hospital, Sun Yat-sen University, XU Lihua , HUANG Xuanjie ,   The Emergency and Disaster Medical Center, The Seventh Affiliated Hospital, Sun Yat-sen University
Published: April 2022

Through the nursing care of a patient with severe acute lipogenic pancreatitis complicated with severe pneumonia, the author comprehensively mastered the nursing points and precautions of the disease, and also had a profound understanding of the monitoring and management of this patient. It has also accumulated valuable experience in bed protection and unplanned extubation. In the observation of the effect of sedation and analgesia in patients, new reflections have been triggered through learning and literature search.
LABORATORY PRACTICAL AID AS A TOOL TO REALIZE PRACTICE-ORIENTED APPROACH IN TEACHING PHYSICS AT HIGHER SCHOOL
Authors:   International Institute of Design and Service, Kondakov S.A.
Published: April 2022

The article deals with the problem of realizing the content of physical education, which is related to the fact that the knowledge being formed remains unclaimed, completely divorced from the need to apply it in reality. The essence of the introduction of laboratory and practical aids into the educational process of studying physics is revealed. One of the examples of a practical task introduced into the educational process to implement this aid is given. It is concluded that laboratory practical aid facilitates the realization of practice orientation principle in the curriculum, increase of the indicators of performance and formation of general professional competences of student’s personality.
Integrated bioinformatics analysis for the identification of hub genes and signaling pathways related to circANRIL
Authors: Qin Qiuyan , Zheng Pengfei , Tu Ronghui , Huang Jiegang , Cao Xiaoli
Published: April 2022

Background

Antisense noncoding RNA in the INK4 locus (ANRIL) is located on human chromosome 9p21, and modulation of ANRIL expression mediates susceptibility to some important human disease, including atherosclerosis (AS) and tumors, by affecting the cell cycle circANRIL and linear ANRIL are isoforms of ANRIL. However, it remains unclear whether these isoforms have distinct functions. In our research, we constructed a circANRIL overexpression plasmid, transfected it into HEK-293T cell line, and explored potential core genes and signaling pathways related to the important differential mechanisms between the circANRIL-overexpressing cell line and control cells through bioinformatics analysis.

Methods

Stable circANRIL-overexpressing (circANRIL-OE) HEK-293T cells and control cells were generated by infection with the circANRIL-OE lentiviral vector or a negative control vector, and successful transfection was confirmed by conventional flurescence microscopy and quantitative real-time PCR (qRT-PCR). Next, differentially expressed genes (DEGs) between circANRIL-OE cells and control cells were detected. Subsequently, Gene Ontology (GO) biological process (BP) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to explore the principal functions of the significant DEGs. A protein–protein interaction (PPI) network and competing endogenous RNA (ceRNA) network were constructed in Cytoscape to determine circularRNA (circRNA)- microRNA(miRNA)-messenger RNA (mRNA) interactions and hub genes, and qRT-PCR was used to verify changes in the expression of these identified target genes.

Results

The successful construction of circANRIL-OE cells was confirmed by plasmid sequencing, visualization with fluorescence microscopy and qRT-PCR. A total of 1745 DEGs between the circANRIL-OE group and control were identified, GO BP analysis showed that these genes were mostly related to RNA biosynthesis and processing, regulation of transcription and signal transduction. The KEGG pathway analysis showed that the up regulated DEGs were mainly enriched in the MAPK signaling pathway. Five associated target genes were identified in the ceRNA network and biological function analyses. The mRNA levels of these five genes and ANRIL were detected by qRT-PCR, but only COL5A2 and WDR3 showed significantly different expression in circANRIL-OE cells.
Spatial variability of microzooplankton grazing on phytoplankton in coastal southern Florida, USA
Authors: Millette Nicole , Kelble Christopher , Smith Ian , Montenero Kelly , Harvey Elizabeth
Published: April 2022

Microzooplankton are considered the primary consumers of phytoplankton in marine environments. Microzooplankton grazing rates on phytoplankton have been studied across the globe, but there are still large regions of the ocean that are understudied, such as sub-tropical coastal oceans. One of these regions is the coastal area around south Florida, USA. We measured microzooplankton grazing rates in two distinct environments around south Florida; the oligotrophic Florida Keys and the mesotrophic outflow from the Everglades. For 2-years from January 2018 to January 2020, we set up 55 dilution and light-dark bottle experiments at five stations to estimate the microzooplankton community grazing rate, instantaneous phytoplankton growth rate, and primary production. Our results suggest that microzooplankton are consuming a higher proportion of the primary production near the Everglades outflow compared to the Florida Keys. We also found that changes in phytoplankton growth rates are disconnected from changes in the microzooplankton grazing rates in the Florida Keys. Overall, the data from the Everglades outflow is what would be expected based on global patterns, but factors other than microzooplankton grazing are more important in controlling phytoplankton biomass in the Florida Keys.
Different Substrates on the Reproduction Rate of Earthworm (Eudrilus eugeniae) and NPK Content of Its Castings
Authors: Narita Rovelito , Galagar Cerenia
Published: April 2022

In response to the posing threat of chemically produced crops using synthetic fertilizers for human consumption, organic farming using earthworms in composting has resorted. This study is carried out to determine the effects of locally available substrates on the reproduction rate of earthworms and the NPK content of its castings. It was laid out with seven treatments replicated three times in Completely Randomized Design. Treatments used were 75% goat manure plus 25% of various substrates such as banana leaves, grass clippings, rice straw, legume leaves, cassava leaves, banana bracts, and sawdust. They were shredded, partially decomposed, transferred to the beds for earthworm feeding, and harvested after 45 days. The castings were collected, separated from the biomass, weighed, and were sent for laboratory analysis. The highest reproduction rate of earthworm biomass was in Treatments with sawdust and legume leaves. Treatments with banana bracts and legume leaves had significantly higher Nitrogen and Phosphorous. Higher Potassium content was noted in treatments with sawdust and legume leaves. It is recommended to use 75% goat manure and a combination of legumes leaves and sawdust for a higher rate of reproduction of vermi biomass and higher contents of Nitrogen, Phosphorous, and Potassium (NPK) in the castings.
Story Retelling (SR) Technique in Improving Reading Comprehension of Sixth-Graders
Authors: Risonar Cupid Jones , Digamon Jayson , De La Peña Jerome , Delima Ronnel Rey
Published: April 2022

The PHIL-IRI results of the sixth graders during their fifth grade were seriously alarming. All learners were identified as frustration readers. Thus, this study aimed to improve sixth graders' reading comprehension through Story Retelling (SR) technique. The study used a pretest-post-test quasi-experimental design consisting of two intact classes with 43 grade 6 learners. One class was exposed to SR Technique, while the other was exposed to the traditional method. The comparison of posttest results revealed no significant difference in the comprehension level of the respondents with (p>.01) between groups. The data proved that SR did not significantly enhance the reading comprehension of the learners. There was a slight increase in the posttest mean scores of the experimental group. However, the increase was not significant. It showed that the learners lacked solid general knowledge and vast vocabulary, which are essential in reading. The interviews discovered that the learners were not exposed to the English language and were not adequately monitored about their academic progress. These pre-existing background conditions significantly affected the intervention, preventing a significant difference in the learners' reading comprehension. Based on the results, it is recommended that the Story Retelling (SR) technique is only introduced to the learners after they learn the basic reading skills, including vocabulary, and establish solid general knowledge. Moreover, the amount of time spent on the intervention added to the undesirable results. Thus, the intervention should be conducted in more than six weeks to achieve better results.
Beach Resorts’ Contribution to the Triple Bottom Line: Economic, Environmental, and Social
Authors: Cano Jesszon , Gimena Judy Ann , Micabalo Kingie , Padillo Elisheba , Siaton Amabella Grace , Ramasola Arlinda
Published: April 2022

This investigation utilized the blended method of research using researcher-designed survey tools. This study was conducted in Anda, Bohol. Using the random sampling technique, sixty respondents provided information on the contribution of the operation of the beach resorts. The study also had nine informants interviewed on the challenges encountered by the beach resorts' operations in their locality. For the analysis of quantitative data, frequency count, percentage, weighted mean, and thematic analysis for qualitative data. The operation of beach resorts had a high contribution towards economic growth and social development and a moderate contribution towards environmental protection. Lastly, challenges encountered by the stakeholders in the operations of beach resorts in terms of ensuring economic growth were Poor Service Quality, Decreases Guests’ Loyalty, Lack of Transparency in Financial Report, Local Guest Outnumber Foreign Visitors, Marketing Disadvantage due to Inaccessible Location, Unstable Employment, Failure to Comply Legal Obligations and Fishing Ban. In contrast, the challenges in attaining social development were Negative Intercultural Adaptation, Culture and Heritage Disturbance, Inequalities of Resources, Lack of Community Involvement, and Low Public Health Protection. Further, the challenges in ascertaining environmental protection of the beach resorts’ existence in the locality were Weak Environmental Monitoring and Enforcement, Rejecting Environmental Policy, Additional Burden, Minimizes Financial Growth Opportunities and Excessive Fees Discourages Tourists from Return. The beach resorts in the rural location were fully compliant with the proper solid waste management since there are standard operating procedures that they need to perform to ensure customer satisfaction.
Role of Black Salt to Reduce in Hypertension, Reality and Evidence Based Studies
Authors: Sen Naresh , Tanwar Sonal
Published: April 2022

Salt in diet is very important to make our life healthy and energetic. Quantity and quality of salt with appropriate ratio or balance in electrolytes which are responsible for volume of body, blood velocity, for functions of receptors and enzymes, to prevent inflammation, proliferation and to make balance in muscles contraction and nerve conduction through to avoid high stimulation of sympathetic nervous system. Hence, scanning and focus with monitoring and supply of healthy salt in limits may prevent volume overload, renal dysfunction & left ventricular hypertrophy, to prevent cardiac functions, to avoid the weaken gut immunity and also to prevent cerebral oedema, cerebral aneurysm and hypertension cause stroke. Control of salt with intake of low quantity and high quality with more frequency of intervals during 24 hours in required amount of salt in balanced electrolytes may help to avoid high salt sensitivity. Balanced salt intake is also important to avoid volume expansion and obesity with reduction of insulin resistance leads to prevent hypertension and diabetes which are leading risk factors for cardio-renal syndrome, cardiovascular morbidity and mortality. Our data suggested a 2.5-fold higher risk for high blood pressure in sea or white salt users versus black salt or Himalayan rock salt which showed more potassium and magnesium with low sodium ions as compared to sea salt.
The Influence of Modern Lifestyle on the Health of Medical Students in a Medical School in Dominica
Authors: Victoire Schilo La , Ukwandu Stephanie , Ejuone Oghenetega , Monday Esther O.
Published: April 2022

Background: A healthy lifestyle is a way of living that reduces the risk of being severely ill. In 1967, the World Health Organization (WHO) defined health as “of complete physical, mental and social well-being and not merely the absence of disease or infirmity ». An unhealthy diet and lack of physical activity are in the lead for global health risks.

Aim: This study explored the impact modern lifestyle has on the health of medical students

Methods: Our study included a literature review, and a questionnaire consisting of 24 questions which were answered by 76 participants which targeted; diet, exercise regimen, sleep cycle, alcohol, substance use, and technology use.

Results: From the responses, 63.1% of respondents practice a sedentary lifestyle, 68.4% skip breakfast and 35.5% have an unhealthy diet.

Conclusion: There is a need for individuals to pay attention to their daily practices as modern lifestyle can have a negative impact on quality of life.
Soot and Carcinogenesis in Rivers State
Authors: Nyebuchi Jonathan , Achonnwo Kpaluku Chukwuka , Roseline Emeji , Josephine Osiagor
Published: April 2022

Soot is the product of incomplete combustion of hydrocarbons. It is a fine black powdery substance also known as Black Carbon that arises from the burning of substances such as oils, woods, chars, tyres, and other hydrocarbon compounds. This processes leads to the release of various components within the soot particles which have been linked to various diseases. Soot is formed through complex chemical processes and are dispersed by air. The sticky nature of soot allow it to stick to exhaust pipes of power generating set and automobiles. It has also been identified as a major pollutant around the world, with the highest amount being emitted by developing countries. Africa ranks high among the highest emitters of soot and in world, especially with the spike in the activities of artisanal refining of crude oil and gas flaring in the South-South Nigeria, particularly the Niger-Delta. Heavy metals such as Cadmium, Chromium, Lead, Iron, Nickel, and Arsenic have been found to be present in soot and are linked to various types of cancers like the cancers of the lungs, liver, skin, throat, and disease such as diabetes. Many respiratory conditions treated in hospitals within Rivers State has been linked to soot and its component. Further studies predicts that the cases could worsen if the emissions continues. This study is focused on black soot and its carcinogenesis in Rivers State.
Post-injection Complications. Nicolau Syndrome as a Consequence of Local Irritant Effects of Drugs, Including Antiseptics, Local Anesthetics, NSAIDs, Steroids and Anticoagulants
Authors: Urakov Aleksandr , Urakova Natalya , Fisher Evgeny , Bashirov Ilnur , Nurlanova Sabina , Klimovich Anastasia , Fakhretdinova Albina , Bakirov Anvar , Balametova Regina , Samorodov Aleksandr
Published: April 2022

It has been shown that some drugs considered to be of good quality today can cause an iatrogenic disease known as Nicolau syndrome. Nicolau syndrome is a rare cutaneous drug reaction occurring after injection many drugs. This disease has been found to be caused by the very strong local irritant activity of drug solutions. It turned out that the standard for assessing the quality of drug solutions does not include assessment of their osmotic activity and the strength of their local irritating effect on various tissues during injection. At the same time, drug solutions produced by different pharmaceutical companies may contain, in addition to the main ingredients, other ingredients (hydrochloric acid, sodium hydroxide, propylene glycol, etc.). Very often the additional ingredients increase the osmotic activity of the drug solution, which is not controlled today, so it remains unknown.  This is why drug solutions produced by some pharmaceutical companies can have hypertonic activity, which can sometimes by ignorance reach values that are incompatible with the vital activity of human body tissue cells. Therefore, injections of such drug solutions can have a very strong dehydrating effect on the tissue cells at the injection sites, have a local irritating and cauterizing effect. It has been shown that even steroid solutions in some manufacturers may have excessive hypertonic and acidic activity, which gives them a local irritating effect. This is why in some cases the injection of a steroid solution does not eliminate, but rather increases local inflammation and causes necrosis. Therefore, to exclude postinjection necroses and abscesses, it is proposed to include an assessment of the osmotic activity and local irritant effect of drug solutions in the drug quality control standard and to prohibit the injection of drug solutions with excessive hypertonic activity.
Filling Octahedral Interstices by Building Geometrical Defects to Construct Active Sites for Boosting the Oxygen Evolution Reaction on NiFe2O4
Authors: Peng Yang , Huang Churong , Huang Jingle , Feng Min , Qiu Xinzhuo , Yue Xin , Huang Shaoming
Published: April 2022

Owing to the faster kinetics and outstanding catalytic performance, spinel oxides are regarded as a potential non‐precious metal electrocatalyst for oxygen evolution reaction (OER). Regulation of the geometrical structures of the spinel oxides is one of the most effective approaches for enhancing their OER performance. However, more wide and deep investigations remain because of the structural complexity of spinel oxides, for example, how to fill the unoccupied octahedral interstices to construct a large number of active sites for boosting the OER. Herein, iron foam (IF) supported NiFe2O4 nanocubes with high occupancy at octahedral sites (HOoct‐NFO NC/IF) are synthesized by hydrothermal method followed by anchoring and annealing. Detailed structural characterizations indicate that the foreign Fe cations can be filled into the octahedral interstices along the geometrical defects channel of transition metal cations coordinated with six oxygen anions (TMO6) by etching TMO6 units with an anchoring agent. As a result of the increasing of TMO5 sites with better activity and tuning of the electronic structures, the as‐fabricated HOoct‐NFO NC/IF electrocatalysts exhibit excellent performance for OER with overpotentials of 260 and 310 mV to reach 10 and 400 mA cm−2, respectively. Meanwhile, the catalysts show faster kinetics and superior stability.
Deep Neural Network with Data Cropping Algorithm for Absorptive Frequency‐Selective Transmission Metasurface
Authors: Wang Jiayi , Xi Rui , Cai Tong , Lu Huan , Zhu Rongrong , Zheng Bin , Chen Hongsheng
Published: April 2022

Deep neural networks (DNNs) are widely used in designing a metasurface; however, data acquisition from simulations is expensive in terms of time and effort. Inspired by image cropping, a data cropping algorithm is proposed that can significantly reduce the simulation time required in the DNN pre‐training process. The algorithm crops the simulated data and adds random data to augment the amount of the dataset. By applying the proposed target‐driven DNN, an absorptive frequency‐selective transmission (AFST) metasurface structure with a low profile and a broad transmission band is designed. A transmission band from 7.5 to 14 GHz and an absorption rate as large as 0.75 beyond the transmission band are observed. The proposed method provides an efficient strategy to design metasurfaces and a fast solution to the electromagnetic inverse design problem.
Growth of N‐Heterocyclic Carbene Assemblies on Cu(100) and Cu(111): From Single Molecules to Magic‐Number Islands
Authors: Navarro Juan J. , Das Mowpriya , Tosoni Sergio , Landwehr Felix , Koy Maximilian , Heyde Markus , Pacchioni Gianfranco , Glorius Frank , Roldan Cuenya Beatriz
Published: April 2022

N‐Heterocyclic carbenes (NHCs) have superior properties as building blocks of self‐assembled monolayers (SAMs). Understanding the influence of the substrate in the molecular arrangement is a fundamental step before employing these ligands in technological applications. Herein, we study the molecular arrangement of a model NHC on Cu(100) and Cu(111). While mostly disordered phases appear on Cu(100), on Cu(111) well‐defined structures are formed, evolving from magic‐number islands to molecular ribbons with coverage. This work presents the first example of magic‐number islands formed by NHC assemblies on flat surfaces. Diffusion and commensurability are key factors explaining the observed arrangements. These results shed light on the molecule‐substrate interaction and open the possibility of tuning nanopatterned structures based on NHC assemblies.
Identification of 9H‐purin‐6‐amine derivatives as novel aldose reductase inhibitors for the treatment of diabetic complications
Authors: Zhu Junkai , Qi Gang , Kuang Yan , Zhao Yating , Sun Xinjie , Zhu Changjin , Hao Xin , Han Zhongfei
Published: April 2022

A series of 9H‐purin‐6‐amine derivatives as aldose reductase (ALR) inhibitors were designed and synthesized. Most of these derivatives, having a C6‐substituted benzylamine side chain and N9 carboxylic acid on the core structure, were found to be potent and selective ALR inhibitors, with submicromolar IC50 values against ALR2. Particularly, compound 4e was the most active with an IC50 value of 0.038 μM, and it was also proved to be endowed with excellent inhibitory selectivity. The structure–activity relationship and molecular docking studies highlighted the importance of the carboxylic acid head group along with different halogen substituents on the C6 benzylamine side chain of the 9H‐purin‐6‐amine scaffold for the construction of strong and selective ALR inhibitors.
Objective measurement of vocalizations in the assessment of autism spectrum disorder symptoms in preschool age children
Authors: Moffitt Jacquelyn M. , Ahn Yeojin Amy , Custode Stephanie , Tao Yudong , Mathew Emilin , Parlade Meaghan , Hale Melissa , Durocher Jennifer , Alessandri Michael , Perry Lynn K. , Messinger Daniel S.
Published: April 2022

Assessment of autism spectrum disorder (ASD) relies on expert clinician observation and judgment, but objective measurement tools have the potential to provide additional information on ASD symptom severity. Diagnostic evaluations for ASD typically include the autism diagnostic observation schedule (ADOS‐2), a semi‐structured assessment composed of a series of social presses. The current study examined associations between concurrent objective features of child vocalizations during the ADOS‐2 and examiner‐rated autism symptom severity. The sample included 66 children (49 male; M = 40 months, SD = 10.58) evaluated in a university‐based clinic, 61 of whom received an ASD diagnosis. Research reliable administration of the ADOS‐2 provided social affect (SA) and restricted and repetitive behavior (RRB) calibrated severity scores (CSS). Audio was recorded from examiner‐worn eyeglasses during the ADOS‐2 and child and adult speech were differentiated with LENA SP Hub. PRAAT was used to ascertain acoustic features of the audio signal, specifically the mean fundamental vocal frequency (F0) of LENA‐identified child speech‐like vocalizations (those with phonemic content), child cry vocalizations, and adult speech. Sphinx‐4 was employed to estimate child and adult phonological features indexed by the average consonant and vowel count per vocalization. More than a quarter of the variance in ADOS‐2 RRB CSS was predicted by the combination of child phoneme count per vocalization and child vocalization F0. Findings indicate that both acoustic and phonological features of child vocalizations are associated with expert clinician ratings of autism symptom severity.

Lay Summary

Determination of the severity of autism spectrum disorder is based in part on expert (but subjective) clinician observations during the ADOS‐2. Two characteristics of child vocalizations—a smaller number of speech‐like sounds per vocalization and higher pitched vocalizations (including cries)—were associated with greater autism symptom severity. The results suggest that objectively ascertained characteristics of children's vocalizations capture variance in children's restricted and repetitive behaviors that are reflected in clinician severity indices.