bluuebunny/crossref_metadata_2025 huggingface dataset:
Middle school students’ attitudes toward physical activity and physical education, intentions, and physical activity behavior
Authors: Mercier Kevin , Simonton Kelly , Centeio Erin , Barcelona Jeanne , Garn Alex
Published: June 2022

Schools are focusing more on promoting physical activity (PA) before, during, and after the school day, to combat the risk factors associated with sedentary behaviors. Since attitudes impact decisions to be physically active, identifying how PA attitudes relate to established attitudes toward physical education (PE), as well as PA intentions and behaviors are important—and thus the focus of this study. Middle school students ( N = 948; 45% female) completed PA behavior, PA intention, and PA and PE attitude surveys. Findings provided a better understanding of attitude theory with the identification of relationships between PA attitudes and PE attitudes, behavioral intention, and behavior. Multiple regression model results showed significant relationships between positive PA attitudes, negative PA attitudes, and PE attitudes with behavioral intention, and self-reported PA behavior. Differences between positive and negative PA attitudes were identified with positive PA attitudes most predicting intention. The results provide guidance for developing learning experiences aimed at promoting attitudes toward PA.
Engaging children, young people, parents and health professionals in interviews: Using an interactive ranking exercise within the co-design of multimedia websites
Authors: Martin-Kerry Jacqueline , Higgins Steven , Knapp Peter , Liabo Kristin , Young Bridget
Published: June 2022

When planning paediatric trials, it is important to consider how best to communicate with children and young people (CYP) so they understand what they are taking part in. It is also important to consider what information they need. Involving CYP as research participants leads to research that is more relevant although it can be difficult to engage CYP in qualitative research to improve trial materials due to the topic area. This paper describes how a visual ranking exercise within qualitative interviews acted as a helpful conduit to engaging discussions to inform a co-designed website with information for trial participants. 40 people participated in interviews during which the ranking exercise was used (11 CYP aged 9–18 years, 14 parents, 15 professionals). We found the ranking exercise supported participant engagement and prevented them feeling that particular responses were expected. It also enabled participants to discuss their ranking (and decisions behind this) with other participants and the researcher. Co-design interviews with CYP that use interactive exercises such as ranking are likely to elicit richer data than those relying on traditional questioning techniques.
Gas chromatography-mass spectrometric determination of organic acids by ion pair liquid extraction followed by in-situ butylation from aqua feed samples
Authors: Talari Kalpana , Ganji Sai Krishna , Mutyam Satish , Tiruveedula Raja Rajeswari
Published: June 2022

A rapid and sensitive analytical method was developed to quantitatively determine organic acids (OAs) from fish feed samples extracted by ion-pair (IP) solvent extraction, followed by in-situ butylation and gas chromatography-mass spectrometric (GC-MS) analysis. The extraction of OAs was carried out with acetonitrile containing 10 mM tetrabutylammonium hydroxide (TBAH), and the analytes were derivatized to their butyl esters in the injection port of the GC-MS system. The developed method was validated in the range of 1–5000 ng/g, with recoveries ranging from 93–117%. The limit of detection (LOD) and limit of quantification (LOQ) of the method was 1–5 ng/g and 2–10 ng/g, respectively, yielding good linearity (R2 > 0.9990) and precision with a relative standard deviation less than 10%. The proposed method was successfully applied to analyze OAs in sinking and floating fish feed samples. The analyzed samples showed the presence of benzoic, succinic, fumaric, glutaric, adipic, and phthalic acids in sinking feed samples; and benzoic, succinic, adipic, phthalic acids in floating feed samples, respectively.
MHD rotational flow of viscous fluid past a vertical plate with slip and Hall effect through porous media: A theoretical modeling with heat and mass transfer
Authors: Ayub Rashid , Ahmad Shahzad , Ahmad Mushtaq
Published: June 2022

As the slip at the solid boundary is an essential attribute for fluid flow in different mechanical situations. Therefore this article aims to explain the slip effect over the free convection and rotating flow of viscous fluid over an extended plate with heat and mass transfer in the presence of magnetic field of the constant magnitude through a porous medium. The respective fluid is chemically reacting fluid hence the effect of chemical reaction with the effect of heat absorption is considered in the development of governing equations. To get the better physical understanding of flow model the governing equations are reduced to dimensionless form. The dimensionless governing equations are solved with aid of Laplace transform and closed form solutions are developed for the thermal, concentration and velocity fields. The real and imaginary components of velocity field are also plotted for the variation of different physical parameters and parametric discussion is posted with assistance of these plotted graphs. In the light of parametric discussion it is concluded that with heat and mass transfer there is more bouncy effect in flow domain. Further in the presence of hall effect fluid speeds up while it is slow down with increasing value of magnetic and slip parameters
Infrared nondestructive detection of defective visible-reflective solder joints in solenoid coil connectors
Authors: Dong Zhao , Oviedo-Tolentino Francisco , Hernandez-Guerrero Abel , Giron-Palomares Benjamin
Published: June 2022

Nondestructive infrared detection of solder defects in solenoid coil connectors was investigated. A detailed experimental setup and a meticulous and repeatable experimental procedure were developed. The experimental methods were firmly based on the application of heat transfer science. Time averaged excess temperature ([Formula: see text]) was the sole discrimination parameter, and a difference larger than 2°C between good and defective solders was conservatively considered for good discrimination. Analysis of variance determined the minimum differences in [Formula: see text] between good and defective solder joints. The effects in discriminability of heating time ( th), time integration interval length ( ti), region of interest (ROI) geometry, and solder radiative properties were investigated. A rectangular ROI tightly enclosing the good solder was found as the best discrimination ROI. Matte black paint increasing radiative emission of solder joints significantly reduced discriminability. The defects were discriminated from the good solder for a rectangular ROI, th = 78 s, and ti = 20 s. Moreover, an excellent total inspection time of 34 s per solenoid coil is obtained by considering a well-controlled inspection environment during manufacturing, severe defects detection, and a possible 1°C difference for discrimination. Several aspects of the novel inspection procedure developed can greatly benefit the thermal imaging scientific community.
Application of phase-field method in corrosion fracture of reinforced concrete
Authors: Zhang Caihong , Xu Wenqiang , Yang Jialing , Cao Kaizhong , Wen Debing , Wang Xusheng
Published: June 2022

The phase-field method was used to simulate the propagation of concrete cracks and failure caused by corrosion and expansion of steel bars, which provides ideas for accurate simulation of the corrosion failure process of reinforced concrete (RC) and evaluation of structural durability. In this study, the entire process of corrosion and expansion of steel bars, resulting in cracks and finally falling off of the concrete protective layer, was successfully simulated. The simulation results were in good agreement with the actual observations. By setting different thicknesses of the protective layer, it was found that the thickness of the concrete protective layer had no obvious effect on limiting concrete cracks caused by the corrosion of steel bars. However, increasing the thickness of the protective layer can delay the speed of crack propagation. Simultaneously, considering the corrosion and expansion of multiple steel bars, according to the thickness of the protective layer and the spacing between the reinforcing bars, two forms of wedge-shaped cracking and laminar spalling of the protective layer are simulated. The simulation result is consistent with the actual observation phenomenon. This fully illustrates the possibility of using the phase-field method to simulate the corrosion fracture of RC and provides a reference for the engineering design and durability research of concrete structures.
Dynamic parameters identification of rolling joints based on the digital twin dynamic model of an assembled ball screw feed system
Authors: Zhang Wei , Zhu Di , Huang Zhiwen , Zhu Yidan , Zhu Jianmin
Published: June 2022

Currently, due to the rare consideration on the coupling of the various rolling joints and their directional dynamic parameters, and the constraints of the traditional modeling methods, the dynamic modeling precision of the ball screw feed system and the dynamic parameters identification accuracy of the rolling joints are difficult to be further improved. In this paper, a novel method to identify the dynamic parameters of rolling joints based on the digital twin dynamic model of the assembled ball screw feed system is proposed. Firstly, synchronizing information of the physical entity, the geometric model is constructed. Then the finite element analysis (FEA) model is constructed which can simultaneously consider multiple rolling joints and their dynamic parameters at multiple directions. Based on the FEA modal data, the deep neural network (DNN) model is constructed to reflect the mapping between the dynamic parameters and the natural frequencies. Thus, the digital twin dynamic model can be established by fusion of these sub-models. Combining the digital twin-driven and experimental natural frequencies, the optimization model is built, and the dynamic parameters can be identified by particle swarm optimization (PSO) algorithm. Finally, the relative error of dynamic parameters identification is less than 3%, which indicates that the proposed method is feasible, effective, and has greater accuracy.
Prognostic values of the C-reactive protein to albumin ratio and prognostic nutritional index in carotid endarterectomy patients
Authors: Bayram Muhammed , Duman Zihni M , Timur Barış , Aksu Timuçin , Yaşar Emre , Güneysu Elif , Buğra Abdül kerim , Yalçın Lokman , Polat Mücahit , Coşkun Hasan , Gürsoy Mete , Aydın Ünal
Published: June 2022

Objectives

C-reactive protein to albumin ratio (CAR) and prognostic nutritional index (PNI) are novel parameters with proven prognostic importance in the postoperative outcomes of coronary and peripheral vascular diseases. In this study, we aimed to evaluate the ability of CAR and PNI to predict major cardiac and cerebrovascular events (MACCE) during the postoperative period of Carotid artery endarterectomy (CEA).

Methods

A total of 505 carotid endarterectomy patients were retrospectively evaluated. Of 505 patients, 23 patients who died and who experienced myocardial infarction or major neurologic complication in the first 30 days after the operation were included in MACCE group (Group 1). The remaining 482 patients were included in Group 2. Receiver operating characteristics (ROC) curve analysis was used to evaluate preoperative serum albumin value, lymphocytes count, PNI, and CAR to predict the MACCE. The DeLong test was used to compare the area below the curve (AUC) with each of these parameters.

Results

CAR (2.48 ± 1.82 and 1.64 ± 1.37) and CRP (9.98 ± 7.42 and 6.81 ± 5.70) values are statistically higher in Group 1 than in Group 2. PNI (41.59 ± 3.11 and 43.54 ± 4.20) and albumin (40.43 ± 3.15 and 42.35 ± 4.15) values were significantly lower in Group 1 than in Group 2. The accuracy of albumin (AUC: 0.669) in the prediction of MACCE was found to be the highest among CAR (AUC: 0.631), PNI (AUC:0.667), and CRP (AUC:0.631).

Conclusion

Preoperative nutritional and inflammatory status is significantly associated with post-operative outcomes. PNI and CAR can be used for preoperative evaluation, as CEA is recommended for patients who have low possibility of having postoperative major adverse events.
Why Warmth Matters More Than Competence: A New Evolutionary Approach
Authors: Eisenbruch Adar B. , Krasnow Max M.
Published: June 2022

Multiple lines of evidence suggest that there are two major dimensions of social perception, often called warmth and competence, and that warmth is prioritized over competence in multiple types of social decision-making. Existing explanations for this prioritization argue that warmth is more consequential for an observer’s welfare than is competence. We present a new explanation for the prioritization of warmth based on humans’ evolutionary history of cooperative partner choice. We argue that the prioritization of warmth evolved because ancestral humans faced greater variance in the warmth of potential cooperative partners than in their competence but greater variance in competence over time within cooperative relationships. These each made warmth more predictive than competence of the future benefits of a relationship, but because of differences in the distributions of these traits, not because of differences in their intrinsic consequentiality. A broad, synthetic review of the anthropological literature suggests that these conditions were characteristic of the ecologies in which human social cognition evolved, and agent-based models demonstrate the plausibility of these selection pressures. We conclude with future directions for the study of preferences and the further integration of social and evolutionary psychology.
Inter- and intra-rater reliability of the Oberg–Manske–Tonkin classification of congenital upper limb anomalies
Authors: Sletten Ida Neergård , Winge Mona Irene , Hülsemann Wiebke , Arner Marianne , Hansen Karina Liv , Jokihaara Jarkko
Published: June 2022

On two occasions, five surgeons classified a cohort of 150 consecutive patients with congenital upper limb anomalies according to the Oberg–Manske–Tonkin classification (2020 update). We estimated reliability for the main anomaly code by means of Cohen’s kappa (Κ) for ten rater pairs for five common and easily distinguishable anomalies (Group 1), and for all the other anomalies (Group 2). Inter-rater reliability for all patients ( n = 150) was substantial, almost perfect for Group 1 ( n = 64), but only moderate for Group 2 ( n = 86). Intra-rater reliability was higher for all groups. We suggest simplifications to the Oberg–Manske–Tonkin classification and highlight specific requirements for instructions to increase its reliability.

Level of evidence: I
Lobaplatin-based neoadjuvant chemotherapy for triple-negative breast cancer: a 5-year follow-up of a randomized, open-label, phase II trial
Authors: Yan Wenting , Wu Xiujuan , Wang Shushu , He Cheng , Zhong Ling , Tang Peng , Ren Lin , Zhang Ting , Qi Xiaowei , Zhang Yi
Published: June 2022

Purpose:

We report the 5-year follow-up findings of a randomized, open-label, phase II trial of lobaplatin-based neoadjuvant chemotherapy plus adjuvant therapy for triple-negative breast cancer (TNBC).

Patients and methods:

This study included patients aged ⩾18 years with untreated, operable stage I–III TNBC and an Eastern Cooperative Oncology Group performance status of 0 or 1. One group of patients (TE group, n = 99) received four cycles of docetaxel (T, 75 mg/m²) plus epirubicin (E, 80 mg/m²) every 3 weeks, and another group (TEL group, n = 101) received the same treatment with the addition of lobaplatin (L, 30 mg/m2). Two cycles of the corresponding treatments were administered after surgery in both groups. The primary endpoints were total pathological complete response (tpCR) rate and overall response rate (ORR), and the secondary endpoints were disease-free survival, overall survival, and long-term safety. This trial is registered with the Chinese Clinical Trial Registry (ChiCTR-TRC-14005019).

Results:

The median follow-up was 48.2 months (interquartile range: 31.1–60.0). The tpCR rate was 41.4% and 17.8% in the TEL group and TE group, respectively ( p < 0.001). The HR for comparison of DFS between the TEL group and TE group was 0.44 (95% CI: 0.21–0.90, P p = 0﻿.028). The addition of lobaplatin resulted in an HR of 0.44 (95% CI: 0.18–1.02, P = 0.061) for the difference in OS between the two groups. The ORR, which included complete response and partial response, was 92.9% in the TEL group and 74.3% in the TE group ( p = 0.001). The TEL group patients were more likely to develop grade III–IV anemia and thrombocytopenia. No lobaplatin-related deaths or increased risk of long-term toxicity was observed.

Conclusion:

Neoadjuvant lobaplatin therapy can improve the tpCR and ORR rates of TNBC with tolerable side effects and have a tendency to improve the long-term survival.
Immunity-enhancing Micronutrients and Community Pharmacists: An Opportunity to Expand Self-Care Practices among the Public
Authors: Chiu Philip Kwok-Leung , Yau Edward Fook-Wing , Cheung Ching-Lung
Published: June 2022

Background: The urban lifestyle and environment pose a constant immune challenge to city dwellers. A major such challenge is influenza, which creates substantial public health and socio-economic burdens. The global healthcare paradigm has begun emphasizing the importance and cost-effectiveness of self-care in partnership with healthcare professionals such as community pharmacists for the management of mild ailments. For the general public, micronutrient supplementation is an affordable and potentially feasible self-care strategy for immunity enhancement and disease management. At the same time, micronutrient deficiencies are a serious public health concern in both developing and developed areas. Objective: This review focuses on the clinical evidence for the efficacy and safety of three key micronutrients — vitamins C, D and zinc — on respiratory infections. Key findings: These micronutrients are important for optimal immune function through their complementary roles in supporting both innate and adaptive immunity, as well as epithelial barriers. The need to improve public awareness of self-care in prevention and health management is highlighted by recent public health issues and the global fight against antimicrobial resistance. Community pharmacists could play a crucial role in empowering patient autonomy. Conclusion: With this review we aim to offer insights into the supplementation of these micronutrients as a self-care approach to the management of immune health.
Real-world effectiveness and safety analysis of carfilzomib–lenalidomide–dexamethasone and carfilzomib–dexamethasone in relapsed/refractory multiple myeloma: a multicenter retrospective analysis
Authors: Onda Yoshiyuki , Kanda Junya , Kaneko Hitomi , Shimura Yuji , Fuchida Shin-ichi , Nakaya Aya , Itou Tomoki , Yamamura Ryosuke , Tanaka Hirokazu , Shibayama Hirohiko , Shimazu Yutaka , Uchiyama Hitoji , Yoshihara Satoshi , Adachi Yoko , Matsuda Mitsuhiro , Hanamoto Hitoshi , Uoshima Nobuhiko , Kosugi Satoru , Ohta Kensuke , Yagi Hideo , Kanakura Yuzuru , Matsumura Itaru , Hino Masayuki , Nomura Shosaku , Shimazaki Chihiro , Takaori-Kondo Akifumi , Kuroda Junya ,   The Kansai Myeloma Forum
Published: June 2022

Background:

Little is known about the real-world survival benefits and safety profiles of carfilzomib–lenalidomide–dexamethasone (KRd) and carfilzomib–dexamethasone (Kd).

Methods:

We performed a retrospective analysis to evaluate their efficacy and safety in 157 patients registered in the Kansai Myeloma Forum database.

Results:

A total of 107 patients received KRd. Before KRd, 99% of patients had received bortezomib (54% were refractory disease), and 82% had received lenalidomide (57% were refractory disease). The overall response rate (ORR) was 68.2%. The median progression-free survival (PFS) and overall survival (OS) were 8.8 and 29.3 months, respectively. Multivariate analysis showed that reduction of the carfilzomib dose and non-IgG M protein were significantly associated with lower PFS and reduction of the carfilzomib dose and refractoriness to prior bortezomib-based regimens were significantly associated with lower OS. A total of 50 patients received Kd. Before Kd, 96% of patients had received bortezomib (54% were refractory disease). The ORR was 62.0%. The median PFS and OS were 7.1 and 20.9 months, respectively. Based on the multivariate analysis, reduction of the carfilzomib dose and International Staging System Stage III (ISS III) were significantly associated with lower PFS. Grade III or higher adverse events were observed in 48% of KRd cases and 54% of Kd cases. Cardiovascular events, cytopenia, and infections were frequent, and 4 KRd patients died due to heart failure, arrhythmia, cerebral hemorrhage, and pneumonia.

Conclusion:

Our analysis showed that an adequate dose of carfilzomib is important for achieving the best survival benefits in a real-world setting. Adverse effects after KRd and Kd therapy should also be considered.
Relationship between sleep pattern and bone mineral density in patients with osteoporotic fracture
Authors: Zeng Haobin , Li Likang , Zhang Bo , Xu Xu , Li Guowei , Chen Maoshui
Published: June 2022

Background:

Evidence investigating sleep pattern in relation to bone health in elderly participants with osteoporosis remains sparse. We aimed to assess the relationship between sleep pattern incorporating five sleep characteristics (snoring, midnight waking up, insomnia, sleep duration, and daytime napping) and bone mineral density (BMD) in elderly participants with osteoporotic fracture.

Methods:

A cross-sectional study was conducted to include eligible elderly patients from the Department of Orthopedics who were admitted to hospital due to an osteoporotic fracture. Sleep pattern was constructed based on total sleep scores and categorized into healthy, intermediate, and poor pattern groups. Multivariable logistic regression model was used to assess sleep pattern in relation to risk of low BMD.

Results:

A total of 169 elderly patients with osteoporotic fracture were included in this study (mean age: 71.91 years; 87.57% females). There were 36 (21.30%), 107 (63.31%), and 26 (15.38%) patients with healthy, intermediate, and poor sleep pattern, respectively. Compared with healthy sleep pattern, no significant relationship between intermediate sleep pattern and BMD was detected [odds ratio (OR) = 1.72, 95% confidence interval (CI): 0.74, 3.97, p = 0.21), while poor pattern was significantly associated with decreased BMD (OR = 3.50, 95% CI: 1.10, 11.14, p = 0.034).

Conclusion:

The majority of elderly patients with osteoporotic fracture had unhealthy sleep pattern; poor sleep pattern was significantly related to reduced BMD when compared with healthy pattern. Further high-quality evidence is needed to assess and validate the relationship between sleep pattern and risk of low BMD in the elderly.
Effects of antipsychotics on heart rate in treatment of schizophrenia: a systematic review and meta-analysis
Authors: Huhn Maximilian , Arndt Thomas , Schneider-Thoma Johannes , Leucht Stefan
Published: June 2022

Background:

Antipsychotics are the treatment of choice in the therapy of schizophrenia. These drugs can be associated with changes in heart rate, but this question has never been examined systematically.

Objective:

We aimed to analyse changes in heart rate during treatment with antipsychotics using the frequency of tachycardia and bradycardia events.

Design:

For this systematic review and meta-analysis, we included all randomized controlled trials for the acute treatment of schizophrenia comparing antipsychotics head-to-head or with placebo.

Data Sources and Methods:

We searched Embase, MEDLINE, PsycINFO, PubMed, BIOSIS, Cochrane Central Register of Controlled Trials (CENTRAL), WHO International Clinical Trials Registry Platform and ClinicalTrials.gov (last search June 2021). Two authors independently selected studies and extracted data. We conducted pairwise meta-analyses using a random-effects model. Outcomes were tachycardia and bradycardia events.

Results:

We found 469 trials meeting the inclusion criteria. Seventy-seven studies with 16,907 participants provided data on tachycardia or bradycardia events. We found no significant differences between antipsychotics and placebo or between antipsychotics for bradycardia events based on sparse data. Antipsychotics had a higher risk for tachycardia events compared with placebo [ N = 37, n = 7827, risk ratio (RR) = 1.83, 95% confidence interval (CI) = 1.40–2.41], with large differences between the individual substances (iloperidone RR = 14.05, chlorpromazine RR = 4.84, loxapine RR = 4.52, risperidone RR = 3.38, quetiapine RR = 2.64, paliperidone RR = 1.65). Some head-to-head comparisons were also significantly different: olanzapine versus haloperidol RR = 2.87, chlorpromazine versus thiothixene RR = 2.92, quetiapine versus lurasidone RR = 3.22, risperidone versus aripiprazole RR = 4.37, iloperidone versus ziprasidone RR = 4.65).

Conclusion:

Many studies do not report data for cardiac outcomes, but the available evidence indicates that treatment with antipsychotics raises the risk for tachycardia. Therefore, especially patients with cardiac risk factors should be monitored closely during antipsychotic treatment.

Registration:

PROSPERO: CRD42014014919
A giant left atrial myxoma causing left-sided heart failure
Authors: Baba Akiko , Hisata Yoichi , Odate Tomohiro , Yamada Takafumi
Published: June 2022

This report presents a case study on giant left atrial myxoma. Transthoracic echocardiography showed a giant mass in the left atrium of a 53-year-old female patient causing functional mitral stenosis. Tumor resection was performed, and the pathological diagnosis confirmed the atrial myxoma. Postoperative echocardiography showed no evidence of any remaining mass and mitral stenosis.
Epithelioid sarcoma with retained INI1 expression as a cause of a chronic leg ulcer
Authors: Maňáková Tatjana , Hojný Jan , Sedlář Martin , Vočka Michal , Chrz Kristian , Mitáš Petr , Beneš Jiří , Holaj Robert
Published: June 2022

Epithelioid sarcoma is a rare soft-tissue sarcoma typically presenting itself as a subcutaneous or deep dermal mass in distal portions of the extremities of adolescents and young adults. They are frequently mistaken for ulcers, abscesses, or infected warts resistant to standard medical treatment. Patients often develop multiple local recurrences with subsequent metastases. We report a case of a 66-year-old patient with chronic leg ulcer who died of generalization of an epithelioid sarcoma.
A research note: Using ethics memoranda of understanding in community-based research
Authors: Su Celina
Published: June 2022

Because university-based research ethics committees tend to focus on ethical dilemmas common in biomedical research in laboratory settings, a growing number of researchers and community-based organizations have articulated the need for alternatives to such committees in community-based research. While there is a robust academic literature on ethical dilemmas in such social research, there remains a need for practical tools to use in collaborations between communities and researchers. In this research note, I present potential memoranda of understanding between academics and communities that might be used when formal community-based research ethics committees do not exist. I focus on two hypothetical scenarios, in which a researcher works with an established group or organization, and in which a researcher is just one of several researchers working with the same community. I forward a framework that conceptualizes researchers as critical friends of communities in their research, highlighting questions of emotional labor, community benefits, and what I call generative conflicts. I hope that researchers and community-based organizations find this note to be a useful starting point for constructive dialogs on reciprocity in community-based research.
An Analysis of Cause-Related and Social Marketing Strategies in the South African Sport Management Industry
Authors: Moyo Talent , Duffett Rodney , Knott Brendon
Published: June 2022

There is a dearth of sport marketing research investigating the strategic potential of socially responsible sport marketing practices for organizations in the sport management industry. Despite the more recent focus on this the emergent topic within marketing literature, there is a lack of application of cause-related marketing (CRM) and social marketing (SM) strategies in the sport marketing context. Furthermore, these strategies are often confused with corporate social responsibility (CSR). The main purpose of this study was therefore to investigate the adoption of CRM and SM marketing strategies by professional sport organizations (PSOs) in South Africa. An interpretivist philosophy and qualitative approach was adopted for the study, which centered on in-depth interviews conducted with key individuals from six South African PSOs. The findings revealed encouraging evidence of South African PSOs engagement in CRM and SM activities. However, it also revealed that the strategic potential of these elements were not leveraged, mainly due to a lack of understanding of these concepts. The differences and similarities between CRM and SM are identified, according to practitioner understandings. The study contributes to sport marketing literature and practice by proposing a conceptual framework to guide the effective planning and execution of strategic CRM and SM campaigns by PSOs. This framework can assist PSOs to engage in social responsible marketing approaches to improve their marketing performance while maintaining socially responsible business practices.
Psychometric Properties of the Insomnia Severity Index Among Arabic Chronic Diseases Patients
Authors: Al Maqbali Mohammed , Madkhali Norah , Dickens Geoffrey L.
Published: June 2022

Introduction

The Insomnia Severity Index (ISI) is a self-administrated questionnaire most frequently used to assess insomnia in clinical and non-clinical populations.

Objective

To evaluate the psychometric properties of the Arabic ISI among patients diagnosed with chronic diseases.

Methods

A cross-sectional and descriptive correlational design was used. A total of 1,005 patients with chronic diseases completed the seven items of the Arabic ISI version. The scale was assessed in terms of acceptability, internal consistency, and validity. Construct validity was explored with the use of principal factor analysis and confirmatory factor analysis, to examine the dimensional structure of the ISI.

Results

The Cronbach's alpha coefficient for the Arabic ISI was 0.82, which shows good reliability. The total ISI score did not have floor or ceiling effects. There was evidence of discriminate validity. The Principal Component Analysis (PCA) indicated two factors (four items loading on Factor I and three items loading on Factor II). The construct validity of PCA in terms of two factors was explored by confirmatory factor analysis to examine the dimensional structure of the ISI. The confirmatory factor analysis showed an absolute fit for the two-factor model.

Conclusion

The results support the two-factor structure of ISI. The Arabic version of the ISI demonstrated good reliability and validity for assessing insomnia in patients diagnosed with chronic diseases.
Do Same-Gender Peers in the Classroom Have Heterogeneous Impacts on Male and Female Students?
Authors: Smith Emil , Andersen Ida Gran
Published: June 2022

The authors investigate if same-gender peers in the immediate learning context have heterogeneous associations with academic outcomes of male and female students. By applying within-student across-subjects models to data from 44 countries in the Trends in International Mathematics and Science Study, the authors examine “situational” within-classroom differences between immediate (peer) learning environments for the same student. The results show, first, that student outcomes are correlated primarily with traits of same-gender peers and, second, that different peer traits have diverse associations with student outcomes. Because of the empirical design, the authors are able to hold factors such as the socioeconomic composition of peers and friendships constant. These findings highlight the importance of gender in the peer influence process in the classroom as well as the diverse channels through which peer traits operate.
A Biomechanical Analysis of Shoulder Muscle Excursions During Abduction, After the Treatment of Massive Irreparable Rotator Cuff Tears Using Superior Capsular Reconstruction (SCR), Bursal Acromial Reconstruction (BAR), and SCR with BAR
Authors: Labib Michael , Amirouche Farid , Pradhan Sonia , Bobko Aimee , Koh Jason
Published: June 2022

Introduction

Current understanding of the biomechanical effects of treatment options for irreparable rotator cuff (RC) tears is lacking. This study examines how shoulder muscle lengths and excursions are affected by superior capsular reconstruction (SCR), bursal acromial reconstruction (BAR), and SCR with BAR, following a complete supraspinatus tear.

Method

Six fresh-frozen cadaveric shoulders were examined. Deltoid and RC muscle lengths were measured at 0, 30, 45, 60, and 90° of shoulder abduction under six conditions: (1) intact, (2) partially torn supraspinatus, (3) completely torn supraspinatus, (4) SCR, (5) SCR with BAR, and (6) BAR. Muscle excursions from 0–90° of abduction were then calculated.

Results

Subscapularis muscle lengths after SCR, BAR, and SCR with BAR were significantly greater (post-hoc Tukey HSD test; p < .01) compared to the other conditions. Supraspinatus, infraspinatus, teres minor, and deltoid lengths were not significantly different (ANOVA test; p > .01) between the conditions. All muscle excursions remained statistically similar between the conditions (ANOVA test; p > .01).

Conclusion

These findings demonstrate that the use of SCR, BAR, or SCR with BAR for a complete supraspinatus tear, may increase subscapularis muscle length while maintaining other shoulder muscle lengths. An increase in subscapularis length can allow for more effective subscapularis muscle strengthening and increased compensatory function in the long term. Additionally, all shoulder muscle excursions are preserved after partial or complete supraspinatus tears and after SCR, BAR, or SCR with BAR. Therefore, these surgical treatments can initially normalize shoulder muscle function during 0–90° of abduction, after an irreparable supraspinatus tear.
The Lateral Fibular Stress Test: High Variability of Force Applied by Orthopaedic Surgeons in a Biomechanical Model
Authors: Ingall Eitan M. , Kaiser Philip , Ashkani-Esfahani Soheil , Zhao John , Kwon John Y.
Published: June 2022

Background:

The lateral fibular stress test (LFST), also known as the hook or Cotton test, is commonly performed to assess syndesmotic instability intraoperatively. Several studies have used 100 N as the force applied when performing the LFST to detect syndesmotic instability, though no evidence-based requisite force has been described for the test. We hypothesize that surgeons do not apply force uniformly or consistently when performing the LFST and that substantial variation exists. Fundamentally, this could lead to inconsistent diagnosis of syndesmotic instability as surgeons may not be applying the force in a consistent manner.

Methods:

A biomechanical ankle model consisting of an industrial force gauge attached through a SawBones model was fashioned. Orthopaedic attending surgeons and trainees were asked to perform a series of LFSTs and to simulate the force they typically apply intraoperatively. Basic demographic data were collected on each participant.

Results:

Thirty-three surgeons participated in the study, including 18 trainees. The median (IQR) force applied during the LFST was 96.42 (71.42-126.33), 87.49 (69.19-117.40), 99.99 (79.91-137.49), for the pooled group, attendings, and trainees respectively. More than half (54.5%) of all trials were less than 100 N (57.8% of surgeons, 51.8% trainees). Intraobserver correlation was excellent within the overall cohort (0.92, P < .001), trainees (0.90, P < .001), and attendings (0.94, P < .001), respectively. Interobserver reliability was fair among the overall cohort (κ =0.28, P = .49), and poor between the attendings (κ = 0.11, P = .69) and the trainees (κ = 0.05, P = .82), respectively.

Conclusion:

Our study demonstrates that the amount of force applied by typical surgeons when performing the LFST test is highly variable. Variable force application when performing the LFST may lead to inconsistent detection of syndesmotic instability, which may portend a poorer outcome.

Clinical Relevance:

In this study, we demonstrate the wide variability in the amount of force used during a lateral fibular stress test. High variability of force application when performing the LFST may lead to inconsistent diagnosis of syndesmotic instability, which may portend a poorer outcome. Our findings suggest the need for further investigation into the technical aspects of syndesmotic testing that will permit more reproducible and valid interrogation of the syndesmosis.
Rationale for Nicotinamide Adenine Dinucleotide (NAD+) Metabolome Disruption as a Pathogenic Mechanism of Post-Acute COVID-19 Syndrome
Authors: Block Tabitha , Kuo Jonathann
Published: June 2022

Many acute COVID-19 convalescents experience a persistent sequelae of infection, called post-acute COVID-19 syndrome (PACS). With incidence ranging between 31% and 69%, PACS is becoming increasingly acknowledged as a new disease state in the context of SARS-CoV-2 infection. As SARS-CoV-2 infection can affect several organ systems to varying degrees and durations, the cellular and molecular abnormalities contributing to PACS pathogenesis remain unclear. Despite our limited understanding of how SARS-CoV-2 infection promotes this persistent disease state, mitochondrial dysfunction has been increasingly recognized as a contributing factor to acute SARS-CoV-2 infection and, more recently, to PACS pathogenesis. The biological mechanisms contributing to this phenomena have not been well established in previous literature; however, in this review, we summarize the evidence that NAD+ metabolome disruption and subsequent mitochondrial dysfunction following SARS-CoV-2 genome integration may contribute to PACS biological pathogenesis. We also briefly examine the coordinated and complex relationship between increased oxidative stress, inflammation, and mitochondrial dysfunction and speculate as to how SARS-CoV-2-mediated NAD+ depletion may be causing these abnormalities in PACS. As such, we present evidence supporting the therapeutic potential of intravenous administration of NAD+ as a novel treatment intervention for PACS symptom management.
Sleep Quality of Covid-19 Recovered Patients in India
Authors: Chhajer Raina , Shukla Sunil Dutt
Published: June 2022

Objective:

The second wave of the Covid-19 pandemic in India was widespread and caused psychological distress among the citizens. Hospitals were running at a premium, increasing deaths and trepidation stories were on air by media, this generated sleep disturbances for many. This study aimed to examine the sleep quality of Covid-19 recovered patients in India during the second wave of the pandemic.

Methods:

Patients who had recently recovered from Covid-19 were invited to participate in this cross-sectional study using various social media platforms. An online survey questionnaire, including socio-demographics, health-related information, Covid-19 related information, and the Pittsburgh Sleep Quality Index (PSQI), was administered in June 2021. Descriptive statistics were used to compare the scores among the mild, moderate, and severe groups. ANOVA was used to find the difference between the groups for global PSQI scores.

Results:

A total of 311 participants (261 mild, 45 moderate, and 5 severe) provided usable responses. The Global PSQI score for the overall study sample was 8.22 ± 3.79. In the severe group, scores were higher 16.8 ± 2.59, and statistically significant from mild or moderate groups. Sleep quality of Covid-19 recovered patients was found to be statistically significantly different based on their gender ( P < .001), annual income ( P < .001), employment status ( P < .001), and marital status ( P < .001).

Conclusion:

Females, employment in the private sector, annual income below rupees 11 lakh, and unmarried Covid-19 recovered patients reported poor sleep quality. As our findings indicate poor sleep quality among the Covid-19 recovered patients during the second wave in India, designing psychological interventions is recommended to support their wellbeing post-recovery.
Is arrest for prohibited drug use a prelude to more serious offending?
Authors: Wan Wai-Yin , Weatherburn Don
Published: June 2022

Although they constitute a significant fraction of the workload of most courts, very little research has been conducted on the criminal careers of those who commit minor offences. Such research is important for both theoretical and practical reasons. It is of theoretical importance because the criminal careers of those who commit minor offences may differ significantly from those who commit serious offences. It is of practical importance because the assumed rate of re-offending among minor offenders has a bearing on both the sentence imposed and the question of whether some offences should be decriminalised. Use or possession of a prohibited drug is a common minor offence – and one that many have argued should be decriminalised. Little is known, however, about the criminal careers of those convicted of this offence. We do not know what proportion are rearrested, what further offences (if any) they commit, or what factors affect the rate of offending among those who do have further contact with the criminal justice system. To answer these questions, we examined a cohort of 13,953 people whose first proven offence was for the use or possession of a prohibited drug and examined their criminal careers over an average period of 4.4 years (sd. = 3.4 years, range = 20.8 years). The majority (73%) had no further contact with the NSW criminal justice system. The most common offence among those who did re-offend was another drug possession offence. Significantly higher risks of re-offending were found among those living in areas in the lowest quartile of disadvantage and among those found in possession of cannabis. The implications of these findings are discussed.
Estimating epistemic uncertainty in soil parameters for nonlinear site response analyses: Introducing the Latin Hypercube Sampling technique
Authors: Boushehri Reza , Motamed Ramin , Ellison Kirk , Stanton Kevin
Published: June 2022

This study quantifies the effects of epistemic uncertainty in soil parameters on nonlinear (NL) site response analysis (SRA) results, validated against the data recorded at a well-instrumented geotechnical downhole array located in Japan. To this end, a one-dimensional soil column model of the Service Hall Array (SHA) near the Kashiwazaki-Kariwa Nuclear Power Plant (KKNPP) is developed using the finite element (FE) program LS-DYNA. The dynamic stress–strain relationship is characterized by a modified two-stage hyperbolic (MTH) NL backbone curve formulation capable of capturing soil behavior at both small- and large-shear strains. The model is then validated against the ground motion recordings to capture the model bias. The uncertainties associated with the shear-wave velocity profile (a small-strain soil property) and soil shear strength (a large-strain soil property) are incorporated in NL SRA to quantify their separate and joint randomization effects on the results. This study proposes using the Latin Hypercube Sampling (LHS) method as an efficient alternative to commonly used methods, such as Standard Monte Carlo (SMC), to account for uncertainty propagation in such reliability analysis. Both low-intensity and design-level records from the recordings at the SHA are applied to study the contribution of the small- and large-strain NL dynamic soil properties. Results from 46,200 NL FE analyses (23,100 per input motion) are presented. Measured and predicted site response, using recorded ground motions at this downhole array, is compared to assess the significance of soil parameter uncertainty on the observed ground motion dispersions. It is demonstrated that increasing the number of soft realizations and implementing higher level earthquake intensity lead to higher ground motion dispersion. Unlike past studies in randomization of Vs profiles with the SMC method, the LHS method is shown to have no significant effect on the predicted median surface response spectra and amplification factors (AFs) for this case study.
Preoperative NT-proBNP and LVEF for the prediction of acute kidney injury after noncardiac surgery: a single-centre retrospective study
Authors: Wang Jiaqi , Dong Yehong , Zhao Bingcheng , Liu Kexuan
Published: June 2022

Background

Acute kidney injury (AKI) is one of the most common postoperative complications in noncardiac surgical patients, has an important impact on prognosis and is difficult to predict. Whether preoperative N-terminal pro-brain natriuretic peptide (NT-proBNP) concentrations and left ventricular ejection fraction (LVEF) levels can predict postoperative AKI in noncardiac surgical patients is unclear.

Methods

We included 3,314 patients who underwent noncardiac surgery and had measurements of preoperative NT-proBNP concentrations and LVEF levels at a tertiary academic hospital in China between 2008 and 2018. Multiple logistic regression analysis was used to construct a postoperative AKI risk prediction model for this cohort. Then, NT-proBNP concentrations and LVEF levels were included in the abovementioned model as independent variables, and the predictive ability of these two models was compared.

Results

Postoperative AKI occurred in 223 (6.72%) patients within 1 week after surgery. Preoperative NT-proBNP concentrations and LVEF levels were independent predictors of AKI after adjustment for clinical variables. The area under the receiver operating characteristic curve (AUROC) of the AKI risk predictive model established with clinical baseline variables was 0.767 (95% CI: 0.732, 0.802). When NT-proBNP concentrations and LVEF levels were added to the base model, the AUROC was 0.811 (95% CI: 0.779, 0.843). The addition of NT-proBNP concentrations and LVEF levels improved reclassification by 22.9% (95% CI 10.5–34.4%) for patients who developed postoperative AKI and by 36.3% (95% CI 29.5–43.9%) for those who did not, resulting in a significant overall improvement in net reclassification (NRI: 0.591, 95% CI 0.437–0.752, P < 0.000). The integral discrimination improvement was 0.100 (95% CI: 0.075, 0.125, P < 0.000).The final postoperative AKI prediction model was constructed, and had a good discriminative ability and fitted to the dataset.

Conclusions

Preoperative NT-proBNP concentrations and LVEF levels were independently associated with the risk of AKI after noncardiac surgery, and they could improve the predictive ability of logistic regression models based on conventional clinical risk factors.

Trial registration

The protocol was preregistered in the Chinese Clinical Trial Registry (ChiCTR1900024056).