bluuebunny/crossref_metadata_2025 huggingface dataset:
NEOLOGISMS IN UKRAINIAN TRANSLATIONS OF BOŁESŁAW LEŚMIAN POETRY
Authors: Pavlinchuk T.
Published: April 2023

The article deals with peculiarities of translations of neologisms of the Polish poet Bolesław Leśmian’s works into Ukrainian. Translation of Bolesław Leśmian’s poetry into different languages meets difficulties due to the fact, that a lot of author’s neologisms appear in it and motivate translator to thoroughly analyze the peculiarities of author’s derivation and make their own strategy of neologisms’ reproduction in the language of translation. Study of experience of translators this poet’s works into Italian, English and other languages helps literature researcher to systematize and accommodate difficulties which appear on the way of choosing the corresponding lexeme or making up a neologism. Due to familiarization with the artist’s worldview, the style of his writing, features of making up neologisms and utilizing them in the original texts, conclusions about making up and functioning of the new words in the texts of translation have been formulated. The translator of B. Łeśmian’s poetry into Ukrainian Marianna Kiianovska utilized all spectrums of possibilities of Ukrainian derivation and actual productive formants in order to make up neologisms and reproduce the style of poet’s writing. The examples from the book of selected poems "Angels" have been given in the article and the peculiarities of appearing of Ukrainian neologisms belonging to different parts of speech (nouns, pronouns, verbs, adjectives, numerals, adverbs) have been analyzed. The similarity of both Ukrainian and Polish languages allows to take advantage of the derivations formants of source language to transfer Polish lexemes to Ukrainian speaking field and to make up new words, which are analogous to existing, even on condition that formant loses its productivity. The ways of derivation, impact of the idea of original texts and original author’s neologisms on the translator’s strategy and word selection, the role of tropes, idioms and analogies in the process of new words appearing have been researched.
LANGUAGE MEANS OF MEDICAL ADVERTISING DISCOURSE
Authors: Tsupikova O. , Avramenko A.
Published: April 2023

The article updates the opinion of the relevance of a comprehensive study of the phonetic and lexical units functioning peculiarities in medical advertising discourse as a means to influence the consciousness of a potential consumer. The linguopragmatic orientation of linguistic means in the given discourse is revealed and their frequency of use in medical advertising texts is determined.
It has been proven that phonetic and lexical means of expression have the significant suggestive potential for creating an effective advertising discourse. They are used to enhance the emotional impact of the advertising message, attract the attention of the addressee, and stimulate memorization of the content of the text. Due to phonostylistic means, a bright image of a medicine is created.
The peculiarities of the phonetic means functioning were investigated through the analysis of the most common techniques: rhyme, alliteration, assonance, anaphora, epiphora, onomatopoeia, phonemic repetition, and anadiplosis. The features of the lexical means persuasive effect on the recipient are considered on the example of the most commonly used stylistic figures, namely: metaphor, metaphorization, epithet, comparison, antonyms, euphemisms, anaphora, epiphora, inversion, oxymoron, wordplay (pun), etc.
It was established that phonetic and lexical means serve to achieve the advertiser's manipulative goal. The use of expressive techniques in medical advertising discourse is aimed at quick involuntary memorization of the advertised medicine. The phonostylistic means increase the expressiveness of the advertising text, stimulate the addressee's interest, contribute to the coherence of statements, and have a mnemonic and suggestive effect, which contributes to the realization of the addressee's motivational goal.
The methodological basis of the research consists of descriptive, functional, structural and semantic, quantitative and statistical methods.
More than 400 advertising texts from the Ukrainian mass media (television, Internet) and printed advertising publications (booklets, leaflets) became the material for linguistic investigation.
THE IMAGOLOGICAL SINUSOID OF "PILIGRIMAGE TO THE EAST FROM 1724 TO 1747" BY V. HRYHOROVYCH-BARSKYI
Authors: Kovpik S.
Published: April 2023

The paper deals with the peculiarities of the literary narration in the pilgrimage work by V. Hryhorovych-Barskyi "Pilgrimage...", represented through the prism of binary oppositions, in particular the antithesis "native / foreign". This study shows the attempt to investigate the process of perception and comprehension of cultural facts connected with different nations of the author-narrator and already formed stereotypes in the Ukrainian environment of the Baroque period. The article emphasizes on the ways how to determine the textual tools of embodying the "foreign" in the text of the literary work and interpret them in the context of national and cultural identity.
The article notes that the main principle of reflecting everything that V. Hryhorovych-Barskyi saw should be characterized as the "true objectivism". The writer compares typical Ukrainian traditions related to making bread with Italian traditions, focusing on the fact that Italian bread differs significantly from the Ukrainian one in taste. He also draws attention to the differences in the communication of residents belonging to the same region, as well as the benefits of residents settling in hotels, etc.
Watchful eyes of the author-narrator are concentrated on routine practices of many European cities in the 18th century. This paper shows that "Pilgrimage..." by V. Hryhorovych-Barskyi belongs to the pilgrimage literature or travel literature, which has specific features, such as: freedom of narrative strategies, the presence of a foreign locus, stylistic freedom. The narrator in this literary work acts as an observer. Consequently the thematic field of the text is not built exclusively around the meeting of native and foreign cultures. The author of "Pilgrimage..." only records the differences between Native and the Strange without making any evaluative judgments.
The article highlights that the names of some subsections of "Pilgrimage..." have an imagological aspect, for example, "About the glorious city of Rome, about local customs", where the lexeme "local" attracts the recipient’s attention to content that will describe an exact and specific area.
Sometimes the narrator still resorts to subjective evaluations in the formation of the heteroimage of the Strange, which considerably highlights the author’s imagological position.
GENRE-STYLE PARADIGM OF THE MODERN UKRAINIAN MYSTICAL STORY OF THE 21ST CENTURY
Authors: Kravchenko Y.
Published: April 2023

The article presents an overview of the peculiarities of the modern Ukrainian mystical story as a literary genre. It also analyzes the problem of a clear definition of the term "mystical story", since there is no differentiation of this genre in modern literature, which would allow us to talk about its differences from other types of stories. The specifics of the interpretation of the mysticism in philosophical, religious and literary contexts are studied on the basis of the works of Ukrainian and foreign scientists. The genre attribution of the mystical story is outlined in comparison with the above mentioned genre categories (magical realism and whimsical prose). The article emphasizes the fact that the varieties of the short story as a genre of short prose have practically not been studied in the field of literature: for the most part, short stories have been considered only in comparison with other prose genres, while there are almost no attempts to classify the varieties of short stories. The paradigm of traditional images, characteristic of the Ukrainian mystical tradition and folklore (Blud, chort, domovyk) is considered. Stories from the collection "Ukrainian mysticism" are compared in order to analyze the categories of "mystical" and supernatural images embedded in them, attention is drawn to the peculiarities of the interpretation of elements characteristic of Ukrainian oral folk art. Subtypes of other genres present in mystical stories, such as detective and horror, are also distinguished, and the leading motives of such stories are determined (the motive of transformation, the motive of entering the other world, the religious motive, the motive of contrasting the ordinary and the other worlds). In addition, the paper presents the author's classification of mystical stories by genre and thematic characteristics.
ANALYSIS OF THE LINGUISTIC CHARACTERISTICS OF THE MEDIA CORPUS ON THE TOPIC "WAR IN UKRAINE"
Authors: Bilyk K.
Published: April 2023

The article studies the linguistic characteristics of the corpus of media texts on the topic of "war in Ukraine". The research characterizes the phenomenon of media texts in the scientific literature. The article analyzes theoretical and methodological foundations of linguistic characteristics of media texts. The main linguistic characteristics of media texts on the topic of "war in Ukraine" are identified, namely: the prevalence of emotionally colored vocabulary, a significant percentage of lemmas from the categories "presence of anthroponyms", "use of place names", "use of chrononyms", "use of lexical combinations", "use of numerals", "use of abbreviations", but we note a small percentage of news reflecting the category "indication of age categories of participants in events".
Given that the issue of Russia's war with Ukraine, Western partners' support for Ukraine, and new terrorist attacks by Russia have become one of the most important topics in the media, this problem requires a detailed study, namely linguistic, because modern media can perform a manipulative function, changing the interpretation of information in the minds and perceptions of readers. Using the Sketch Engine corpus analysis of media texts on the topic "War in Ukraine" based on the material of the leading Ukrainian online publication "Gazeta po-Ukrayinsky" of 2022-2023, the linguistic features of news reports are analyzed: there are a significant number of abbreviations in the news texts, namely, "Armed Forces" and "Air Defense"; among anthroponyms, the most commonly used word is "Zelensky"; as for place names, a list of lemmas used in the news headline is revealed: "Bakhmut", "Luhansk", "Donetsk", "Bucha", "Russia", "Ukraine", "West"; lexical combinations in which the lemma "personnel" prevails are analyzed; the category "use of numerals" demonstrates that the General Staff provides generalized statistics in the news texts on the topic "War in Ukraine" in accordance with the request, which provoked a small number of news from the category "indication of age categories of participants in the events", and as a result, this category is based on the most sensational reports, especially those that highlight the age and condition of dead or injured children. The article reveals the presence of accurately used Ukrainian military slang in the category of "emotionally colored vocabulary", which has taken root and gained considerable popularity among news texts on the topic of "War in Ukraine" in the online publication "Gazeta po-Ukrayinsky" and in the Internet space in general.
Due to the ambiguity of terms, hidden meaning, and lack of equivalents for neologisms, especially in military topics, there are difficulties with translation and understanding of the text. When selecting equivalents for a term, it is worth using a corpus tool that allows analyzing the word in context, frequency of use, and building a synonymous and antonymic series of words.
The Zangezur corridor as part of the global transport route (against the backdrop of power games in the South Caucasus region)
Authors: Gawliczek Piotr , iskandarov khayal
Published: April 2023

The restoration of historical transport routes and the creation of new ones is a strategic objective of most states in modern times. Located at the intersection of the North–South and East–West transport routes, Azerbaijan is currently recognised as an important transport and logistics hub. Successful cooperation with European Union countries in this field is taking place. The East–West and North–South international transport routes passing through the territory of Azerbaijan are very convenient for cargo transportation in terms of distance and duration. This paper discusses the plausibility of the Zangezur corridor being used (which is mentioned in the tripartite agreement that dates back to 10 November 2020) and highlights its importance as an integral element of the global transit route. A comparative analysis of different transit routes was carried out, and the advantages of opening this corridor for all stakeholders was justified.
Factors Influencing the Selection of Healthy and Unhealthy Diet Behavior in Adolescent Girls in Bandar Lampung
Authors: Dian Isti Angraini  , Izzah Asiah Nurul , Nisa Khairun , Zuraida Reni
Published: April 2023

Adolescence is a period of a transitional development from children to adult women who are generally 10-21 years old. Adolescents have significant physical, psychosocial, and cognitive changes that can affect adolescent dietary behavior. The purpose of this study was to determine the effect of affecting factors on unhealthy dietary behavior in adolescent girls. This research is an analytic observational study, with a cross-sectional design approach using primary data, which was conducted from April to June 2022. The sample is 135 adolescent girls aged 15-21 years old taken using multistage random sampling who met the inclusion and exclusion criteria. The data was obtained by filling out the questionnaire and analyzed by using the chi-square test. The results showed that 56.3% of respondents had unhealthy dietary behavior. The results of the bivariate analysis showed that nutritional status (p = 0.000; PR = 2.072) and body image (p = 0.000; PR = 0.559) influenced unhealthy dietary behavior. Meanwhile, knowledge (p=0,227), age (p=0,158), pocket money (p=0,452), and peers (p = 0.120) did not influence unhealthy dietary behavior. It can be concluded that there is an influence of nutritional status and body image factors on unhealthy diet behavior. Based on the research results, adolescent girls must have a healthy diet according to balanced nutrition guidelines in achieving normal nutritional status and a good body image.
Strengthening Global Health Security: A Review of Lessons Learnt from Indonesia's COVID-19 Response
Authors: Budiman Dicky , Ernawanti  , Chu Cordia
Published: April 2023

The COVID-19 pandemic has revealed how poorly prepared the world is for a pandemic and how easily viruses spread in our interconnected world. The response to COVID-19 in Indonesia has been hampered by a surge in infection and re-infection cases, an ill prepared of healthcare system, low booster vaccination coverage, the emerging of new sub variant, inconsistent implementation of public health measures, and communication barriers. Nevertheless, as infectious disease outbreaks become more frequent, it is hoped that national health security resources will be identified and strengthened. This will enable the nation to keep pace with spreading diseases and become more resilient to future threats. COVID-19 exposes strengths and weaknesses while also creating threats and opportunities. An analysis of the COVID-19 pandemic strategy was conducted using SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis based on Indonesia's experience with the response and countermeasures to COVID-19. The objective of this study is to analyse all the factors involved in the COVID-19 pandemic response so that lessons can be learned towards an effective public health emergency response. The results highlighted strengths, identified weaknesses, and provided recommendations for the future. This would be useful in responding to current threats to global health security and preparing for future ones.
Therapeutic impact of Telomerase Inhibitor Imetelstat: A Literature Review
Authors: Ziedan Mohamed , Salah Dina , Ayman Maha
Published: April 2023

The immortal phenotype of cancer cells is a significant trait, and in the vast majority of malignancies, the enzyme telomerase is essential for sustaining the cancer cells' limitless capacity for replication. The absence of telomerase expression and the lack of an immortal phenotype in normal adult tissues suggest that telomerase is a prospective therapeutic target for the treatment of a variety of tumor forms. At every cell division, telomeres will shrink if telomerase is not active. Apoptosis, cell senescence, and chromosomal instability are initiated when the telomeres become critically short. Telomeres are stabilized in the majority of rapidly expanding cancers by reactivating telomerase. In numerous tumor forms, it has been demonstrated that telomerase inhibition inhibits the development of cancer cells. Telomerase inhibitors have been discovered over the past 10 years as a result of substantial basic research into the mechanisms regulating telomeres, which may offer a potent, nearly universal cancer treatment approach. A short-chain oligonucleotide called imetelstat [GRN163L, Geron Corporation] has a high affinity and specificity for the RNA component of telomerase's template region [hTR or hTERC]. Researchers conduct an examination of articles that are in accordance with the issue to be studied. Articles used in literature review are obtained through the database of international journal providers through PubMed, we investigated clinical studies and discussed what happened in these clinical studies and the extent of the effectiveness of imetelstat in treatment of cancer. Articles proved that imetelstat could enhance cancer treatment. Articles proved that Imetelstat is promising therapeutic agents for cancer treatment. In this review, we suggest that formulating and following treatment, Further studies are needed to determine the related mechanisms to enhance Imetelstat efficacy.
COMPARISON AND CORRELATION OF CARDIOTHORACIC RATIO ON CHEST RADIOGRAPH AND COMPUTED TOMOGRAPHY
Authors: Vikram Badhe Padma , Varrior Ajith , Rawat Jitesh , Sultan Moinuddin , Patil Sanika , Dhulshette Sumeet , Shukla Abhijeet , Kumar Puneeth , Nagwekar Chandranshu , Khot Chandrasekhar , Dahake Aishwarya , Bhogawade Ganesh
Published: April 2023

Chest radiograph is an easily available non invasive tool in evaluation of health. The cardiothoracic ratio (CTR) is commonly used as an indicator
of cardiomegaly in clinical radiology. It can promptly diagnose congestive cardiomegaly apart from other lung and pleural pathologies and also
depicts repsonse to treatment given, like diuretics in heart failure. Although there are better modalities available like echocardiography, computed
tomography and magentic resonance imaging, chest radiography and cardiothoracic ratio are still being used by clinicians, especially in emergency
department, intensive care unit and for frequent follow ups . CTR is calculated by dividing the cardiac diameter (CD) by the thoracic diameter (TD)
as measured on posteroanterior chest radiography (chest PA). CTR of >0.5 is abnormal on an inspiratory breath-hold chest radiograph. The purpose
of this study was to compare the statistical correlation of CTR between chest radiograph with CT and to present real Heart Size (HS), Thoracic Size
(TS), and Cardiothoracic Ratio (CTR) on chest PA and chest AP in the DR system and in computed tomography (CT). The conclusion of the study is
that the measurement of CTR from radiograph & computed tomography (CT) from both axial & coronal reformations were concordant with
another
A RETROSPECTIVE ANALYSIS OF LAPAROSCOPIC REMOVAL OF INFECTED MESH FOLLOWING LAPAROSCOPIC INGUINAL HERNIA REPAIR.
Authors: Pervej Khan Sharik , Gupta Apoorv , Kela Manoj , Datey Sanjay , Narayan Ghanghoriya Shubh
Published: April 2023

Now a days, Laparoscopic repair is the preferred method for repair of
inguinal hernia owing to its safety and reliability. Use of meshes has
been adopted as standard procedure in surgery. 1
hernia repair
Laparoscopic approach which involves closure of hernia with mesh
2
placement is associated with reduced chronic postoperative pain and
numbness, fast return to normal activities, and decreased incidence of
3 hematoma and wound infection. Two approaches to perform
laparoscopic repair include Transabdominal Preperitoneal (TAPP)
2
approach and the Totally Extraperitoneal (TEP) approach
A STUDY OF MANAGEMENT OF DIAPHYSEAL FRACTURES OF BOTH BONES FOREARM WITH DYNAMIC COMPRESSION PLATING
Authors: Kumar Ale Shiva , Vinodh T. , Kumar K Kishore , Rajesh Rajesh
Published: April 2023

The forearm serves an important role in the functioning of the upper extremity. Hence aggressive management through good anatomical reduction
and internal xation of these fractures has become important. The aim of treatment is to re-establish the normal anatomy and good functional
outcome. Early rehabilitation started in the immediate postoperative period to prevent disability to a large extent. The aim of this study is to assess
the results of fractures of shaft of both bones of forearm with dynamic compression plate (DCP).30 patients with acute diaphyseal fractures of the
radius and ulna were treated with open reduction and internal xation with dynamic compression plate and screws at Osmania general hospital,
between November 2016 and April 2019. Cases were taken according to inclusion and exclusion criteria i.e., Adults, both males and females with
diaphyseal fracture of forearm bones above the age of 18yrs. Medically unsuitable and patients not willing for surgery were excluded from the
study. In our series of 30 cases there were 25 males and 5 females, with average age of 32.6yrs. Good or full range of mobility of elbow and wrist
joints with excellent, satisfactory results was present in 28 patients (94%), 1(3%) patient having restriction of elbow motion and pronation and
supination and 1(3%) patient with ulnar non-union which recovered with bone grafting. With rigid/anatomical internal xation, dynamic
compression plate is a good xation for displaced diaphyseal fractures of the forearm bones. Adherence to AO principles, strict asepsis, proper post
operative rehabilitation and patient education are more important to obtain excellent results. Also, external immobilization was not required in cooperative patients.
DEATH DUE TO DELAYED COMPLICATION IN HANGING - A CASE REPORT
Authors: Kumar Atal Devinder , Dixit Praveen , Kumari Mamta , Sharma Sahil , U Aravindan
Published: April 2023

Hanging is one of the most common methods of painless suicide in India. Hanging is a form of asphyxia which is caused by the suspension of the
body by a ligature encircling the neck, where the constricting force is the weight of the body. In most cases of hanging cases, the death of the
individual occurs immediately or the usual average period is about 3 to 5 minutes. Causes of death in case of hanging are asphyxia, venous
congestion, cerebral ischemia, carotid compression or fracture of vertebrae resulting in penetration into the spinal cord. In this article, the authors
report a rare case of a 19-year-old male individual, who attempted suicide by hanging, survived for 7 days in ICU in an unconscious state and then
died after the best efforts of the ICU team. Delayed death in hanging can be due to aspiration pneumonia, oedematous or haemorrhagic swelling of
pharyngeal tissues or aryepiglottic folds, emphysema, infections, oedema of the larynx, lungs and brain pathology like an abscess, hypoxic
encephalopathy, infarction and softening. In post-mortem examination, the doctor must remove the ligating material after carefully preserving the
knot, and look for any marks of injury or struggle that may suggest the violence leading to strangulation. Prolonged resuscitative measures must be
tried in all the victims of attempted hanging, and a guarded prognosis must be described.
OSTEOPOROTIC DISTAL RADIUS FRACTURE: COMPARATIVE STUDY OF SURGICAL OUTCOME TREATED BY EXTERNAL FIXATOR AND VOLAR PLATING
Authors: Shaji Amal , Dey Rahul , Ashraf Shuhail
Published: April 2023

Background and Objective: Distal radius fractures are one of the most common fragility fractures among the osteoporotic population. The
management of distal radius fracture has evolved so much from cast providing neutralization to bridging external xator later by buttress plates.
There is still no clear consensus for management of distal radius fractures among osteoporotic age group. A randomized comparative study was
undertaken to study functional outcome between closed reduction external xations over volar lock plating. 40 patients of distal radius Methods:
fracture belong to the osteoporotic age group admitted in Assam medical college, Dibrugarh were selected. The patients were randomized into two
groups one group treated with closed reduction external xation and other group with open reduction and plating, 20 patients in each group. The
patients were followed up for 6 months and functional outcome was assessed using Green and O'brien scoring. The study comprised of 16 Results:
males and 24 females aged between 50 to 75 years, with mean age of 58 years. The functional outcome score using Green and O'brien scoring on
follow up we got 40% excellent results, 40% good results, 15% fair results and 5% poor results with plating and 20% excellent results, 30% good
results, 40% fair results and 10% poor results with external xation. Open reduction w Conclusion: ith volar locking plate provided stable
anatomical construct, restoration of anatomy, early mobilization and complications were minimal. External xation provide stable xation in par
with open reduction and plating but had more complications such as wrist stiffness, pin tract infections.
Center conditions for a cubic system with two homogeneous in variant straight lines and exponential factors
Authors: Cozma Dumitru
Published: April 2023

In this paper for a cubic differential system with a singular pointO(0,0) of acenter or a focus type, having two homogeneous invariant straight lines and exponentialfactors, we determine conditions under which the singular point is a center.
La importancia del Programa de Donación de Cuerpos en la formación médica antes y después de la pandemia: experiencia de la Escuela de Medicina de la Universidad de Costa Rica
Authors: González Fernández Jéssica , Salazar Sánchez Lizbeth
Published: April 2023

Se expone breve pero puntualmente el desarrollo del Programa de Donación de Cuerpos (PRODOCU) de la Escuela de Medicina de la Universidad de Costa Rica (EM-UCR). El programa se vincula con sucesos históricos de la formación médica en la nación, así como con episodios recientes de la cooperación internacional universitaria. Se cubren algunos beneficios éticos, docentes, de divulgación e investigación de la implementación exitosa del programa. Finalmente, se valora la oportuna adaptación del programa durante la crisis de covid-19.
Modelo conceptual del proceso de adaptación de la educación médica en tiempos de covid-19: experiencia de la Universidad Nacional Mayor de San Marcos
Authors: Podestá Luis , Miranda Eva , Luján Anita , Núñez Manuel
Published: April 2023

Las escuelas de Medicina de todo el mundo, en mayor o menor medida, han procurado en las últimas décadas incorporar reformas en la educación médica. La pandemia ha acelerado este proceso, pero dificultado otros. El aprendizaje virtual de ser complementario a la formación presencial pasó a ser principal, e incluso exclusivo en el proceso de enseñanza–aprendizaje. Se presenta el modelo conceptual que la Facultad de Medicina de la Universidad Nacional Mayor de San Marcos elaboró para planificar, organizar, implementar y evaluar el proceso de adaptación de las actividades académicas. Se describen 2 ejes fundamentales: garantizar la calidad e implementar acciones de capacitación. Se describen 5 estrategias empleadas, según los niveles de medición del modelo de evaluación de la formación de Kirkpatrick, y conforme a los estilos de aprendizaje del Modelo de Kolb. Se implementaron 965 aulas virtuales en el año académico 2020, y se desarrolló un total de 2075 capacitaciones. La percepción de los estudiantes sobre el desempeño de los docentes fue muy alta, 8.77 para el caso de Medicina. Se relata el proceso de adaptación a la virtualidad, con un intensivo proceso de capacitación, y percepción muy elevada por parte de los alumnos sobre la calidad de los procesos académicos desarrollados. Las lecciones de esta experiencia ha de impregnar decisivamente la etapa postcovid, mostrando los aportes de la tecnología, pero sobre todo de las formas renovadas de entender la relación docente-estudiante, los escenarios de formación en la educación médica y el propio desarrollo curricular.
Los retos de las universidades públicas latinoamericanas
Authors: Gutiérrez José María
Published: April 2023

Se analizan los retos que tienen las universidades públicas latinoamericanas. Estas instituciones deben mantener incólume su ethos, centrado en su carácter público y democrático, su autonomía y búsqueda permanente de la excelencia académica y el bien común. Al mismo tiempo, deben analizar críticamente sus acciones, y efectuar las transformaciones que surgen del vertiginoso avance del conocimiento y de las crecientes demandas de los conglomerados sociales, para contribuir al desarrollo de colectividades marcadas por la prosperidad, la equidad, la inclusión y la procura de una vida digna.
Digital Anti-Corruption Typology for Public Sector
Authors: Mutungi Fredrick
Published: April 2023

Many digital anti-corruption tools have not performed well in practice due to their non-alignment with forms of corruption they are supposed to fight against, the persistence of corruption-enabling conditions, activities, and procedures where it occurs, public sector areas where it occurs, anti-corruption principles and conceptual aspects of corruption. This paper aims to fill this gap with an alternative typology of digital anti-corruption in the public sector that helps to decide what digital measures to apply to fight against specific forms of corruption or address specific corruption-enabling conditions within given areas, activities and procedures in the public sector. The main objective of this paper was to highlight anti-corruption typologies and propose an alternative typology for digital anti-corruption. The proposed typology integrates theoretical constructs from the typology of anti-corruption policies and the TASP framework augmented with digital technologies. It includes six main components: categories of digital technologies, forms of corruption, activities and procedures, public sector areas, anti-corruption principles, and conceptual aspects of corruption. The study developed a typology by adhering to the “good” typology blueprint, which involves limiting the scope, defining concepts, and synthesising findings. By scoping review methods, the study identified various digital anti-corruption technologies relevant to the public sector’s corruption and anti-corruption measures. The paper contributes to existing anti-corruption typologies by proposing a multi-dimensional typology focusing on digital anti-corruption that enhances anti-corruption measures. The typology prescribes effective digital anti-corruption solutions for different corruption scenarios like job appointment and promotion based on connections and inflating public payroll with names of non-existent workers. The typology will provide policymakers, adopters of technical solutions and managers of adopting organisations with information to improve the development, design, adoption, and use of digital anti-corruption in the public sector. The typology is grounded in research and policy literature and validated using real-life examples.
In Vitro Probiotic Characteristics of the Lactococcus Lactis Subsp. Hordniae Strain UAB10 Isolated from Aloe Vera
Authors:   Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, 56212, Korea, Lim Hyung Jin , Won Yeong-Seon ,   Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, 56212, Korea, Bak Seon Gyeong ,   Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, 56212, Korea, Lee Soyoung ,   Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, 56212, Korea, Ryu Bomi ,   Major of Food Science & Nutrition, College of Fisheries Science, Pukyong National University, Busan, 48513, Korea, Cha Seon-Heui ,   Department of Marine Bioindustry, Hanseo University, Seosan, 31962, Korea, Kwon Tae Ho ,   Primate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, 56216, Korea,   Department of Functional Genomics, Bioscience of KRIBB School, University of Science and Technology, Daejeon, 34113, Korea, Shim Kyu-Suk ,   Univera Co., Ltd., Seoul, 04782, Korea, Jeon Jisu ,   Univera Co., Ltd., Seoul, 04782, Korea, Kwon Hyuck Se ,   VITECH Co., Ltd., Wanju, 55365, Korea,   Department of Food Science and Technology, Chonbuk National University, Jeonju, 54896, Korea, Lee Seung Woong ,   Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, 56212, Korea, Lee Seung-Jae ,   Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, 56212, Korea,   Department of Applied Biological Engineering, Biotechnology of KRIBB School, University of Science and Technology, Daejeon, 34113, Korea, Rho Mun-Chual ,   Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, 56212, Korea
Published: April 2023

We have isolated 15 bacterial strains from Aloe vera gel. Among them, we selected the Lactococcus lactis subsp. hordniae strain UAB10 based on its inhibition of IL-6-induced STAT3 activation and its ability to adhere to intestinal epithelial cells. UAB10 showed strong inhibition of interleukin-6-induced signal transducer and activator of transcription 3 activation. The UAB10 isolate showed superior adhesion to Caco-2 cells compared with KTCT 3768, a reference L. lactis subsp. hordniae strain. The UAB10 isolate displayed no hemolytic activity and more potent anti-Shigella flexneri activity than KTCT 3768. Furthermore, UAB10 was able to survive better than KTCT 3768 in oxgall-containing De Man, Rogosa, and Sharpe agar media and low-pH De Man, Rogosa, and Sharpe agar media. Finally, UAB10 did not show any resistance against the eight tested antibiotics, including ampicillin, vancomycin, and gentamicin. These results highlight the potential for the use of UAB10 as a commercial probiotic.
Gypenosides Improve Lipid Homeostasis by Regulating Fatty Acid Metabolism in the Liver
Authors:   Key Lab of the Basic Pharmacology of the Ministry of Education, Zunyi Medical University, Zunyi City, Guizhou 563009, China, Wu Zunping ,   The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi City, Guizhou 563009, China, Xu Yanzhe ,   Key Lab of the Basic Pharmacology of the Ministry of Education, Zunyi Medical University, Zunyi City, Guizhou 563009, China, Zhou Ruoyu ,   Key Lab of the Basic Pharmacology of the Ministry of Education, Zunyi Medical University, Zunyi City, Guizhou 563009, China, Liu Hao ,   Key Lab of the Basic Pharmacology of the Ministry of Education, Zunyi Medical University, Zunyi City, Guizhou 563009, China, Ling Hua ,   School of Pharmacy, Georgia Campus-Philadelphia College of Osteopathic Medicine, GA 30024, USA, Du Yimei ,   Key Lab of the Basic Pharmacology of the Ministry of Education, Zunyi Medical University, Zunyi City, Guizhou 563009, China, Lu Yanliu ,   Key Lab of the Basic Pharmacology of the Ministry of Education, Zunyi Medical University, Zunyi City, Guizhou 563009, China, He Yuqi ,   Key Lab of the Basic Pharmacology of the Ministry of Education, Zunyi Medical University, Zunyi City, Guizhou 563009, China
Published: April 2023

We have examined the effect of gypenosides on hepatic lipid metabolism in hyperlipidemic mice. To this end, male mice were placed on a high-fat diet and then administered gypenosides. Compared to the mice on the high-fat diet, the levels of liver index, total cholesterol, and low-density lipoprotein cholesterol in the serum were significantly reduced by gypenoside treatment. Gypenosides influenced the overall profile of 22 hepatic fatty acid metabolism genes significantly. Three genes, Cyp4a10, Cyp4a14, and Cyp4a31, had their mRNA expression altered by about tenfold. As a possible mechanism, the findings suggest that gypenosides regulate lipid homeostasis by influencing fatty acid metabolism and promoting fatty acid ω-oxidation.
Metabolic correction of neurodegenerative pathologies: the role of macronutrients and timing
Authors: Zilberter Yuri , Zilberter Tanya
Published: April 2023

Despite decades of intensive research, effective treatment and prevention strategies for neurodegenerative diseases (NDDs) remain elusive. This review focuses on Alzheimer’s and Parkinson’s diseases and acquired epilepsy suggesting that in their early phase, these progressive pathologies share common or interacting molecular pathways. Indeed, oxidative stress associated with disrupted glucose metabolism is the expected end state of most, if not all, risk factors preceding the onset of major NDDs. This review proposes that the initial oxidative stress in the brain resulting specifically from the hyperactivation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) causes a decline in glucose utilization and is the primary initiating factor of major NDDs. The existing clinical and experimental evidence points to NOX as the primary initiating mechanism shared within the major NDDs. During early oxidative stress, NOX activation is triggered in variable brain cells via multiple pathways, from beta-amyloid to alpha-synuclein, fibrin to glutamate and seizures. Therefore, the treatment strategy should have targeted the activation of NOX, wouldn’t there be a lack of clinically approved selective NOX antagonists? On the other hand, there are promising metabolism-altering approaches via dietary means able to switch energy intake from glucose to ketones, which influences both oxidative stress and glucose utilization and could ameliorate disease progression. The regimen of time-restricted eating appears to be the most feasible, nutritious, and palatable one providing the essential benefits of a ketogenic diet without adverse effects.
Star Formation Variability as a Probe for the Baryon Cycle within Galaxies
Authors: Shin Eun-jin , Tacchella Sandro , Kim Ji-hoon , Iyer Kartheik G. , Semenov Vadim A.
Published: April 2023

We investigate the connection between the regulation of star formation and the cycling of baryons both within and in and out of galaxies. We use idealized numerical simulations of Milky Way–mass galaxies, in which we vary the galaxy morphology and stellar feedback strength. By following individual gas parcels through the disk, spiral arms, and massive star-forming clumps, we quantify how gas moves through the different phases of the interstellar medium (ISM) and forms stars. We show that the residence time of gas in the dense ISM phase (τ
SF), the nature of spiral arms, and the clump properties depend on both the galaxy morphology and stellar feedback. We quantify signatures of the baryon cycle within galaxies using the temporal and spatial power spectrum density (PSD) of the star formation rate (SFR). Stronger stellar feedback leads to more bursty star formation while the correlation timescale of the SFH is longer, because stronger feedback dissolves the dense ISM phase, leading to a more homogeneous ISM and a decrease in τ
SF. The bulge strength has a similar effect: the deep gravitational potential in a bulge-dominant galaxy imposes a strong shear force that breaks apart gas clumps in the ISM; this subsequently inhibits the fragmentation of gas and therefore the star formation in the disk, leading to a decrease in the spatial power on scales of ∼1 kpc. We conclude that measurements of the temporal and spatial PSD of the SFR can provide constraints on the baryon cycle and the star formation process.
Traveling Planetary-scale Waves Cause Cloud Variability on Tidally Locked Aquaplanets
Authors: Cohen Maureen , Bollasina Massimo A. , Sergeev Denis E. , Palmer Paul I. , Mayne Nathan J.
Published: April 2023

Cloud cover at the planetary limb of water-rich Earth-like planets is likely to weaken chemical signatures in transmission spectra, impeding attempts to characterize these atmospheres. However, based on observations of Earth and Solar System worlds, exoplanets with atmospheres should have both short-term weather and long-term climate variability, implying that cloud cover may be less during some observing periods. We identify and describe a mechanism driving periodic clear sky events at the terminators in simulations of tidally locked Earth-like planets. A feedback between dayside cloud–radiative effects, incoming stellar radiation and heating, and the dynamical state of the atmosphere, especially the zonal wavenumber 1 Rossby wave identified in past work on tidally locked planets, leads to oscillations in Rossby wave phase speeds and in the position of Rossby gyres, and this results in advection of clouds to or away from the planet’s eastern terminator. We study this oscillation in simulations of Proxima Centauri b, TRAPPIST-1e, and rapidly rotating versions of these worlds located at the inner edge of their stars’ habitable zones. We simulate time series of the transit depths of the 1.4 μm water feature and 2.7 μm carbon dioxide feature. The impact of atmospheric variability on the transmission spectra is sensitive to the structure of the dayside cloud cover and the location of the Rossby gyres, but none of our simulations have variability significant enough to be detectable with current methods.
Molecular characterisation of three Ixodes (Pholeoixodes) species (Ixodida, Ixodidae) and the first record of Ixodes (Pholeoixodes) kaiseri from Slovakia
Authors: Krumpálová Zuzana , Mangová Barbara , Purgatová Slávka , Didyk Yuliya M. , Kazimírová Mária
Published: April 2023

A study of ticks on wildlife was carried out in the area of Levice, Bratislava, Stupava, and Vrbovce (south-western Slovakia) during 2021 and 2022. Overall, 512 ticks were collected from 51 individuals of six wild mammalian species. Eight tick species were identified, namely Dermacentor reticulatus, D. marginatus, Haemaphysalis inermis, H. concinna, Ixodes ricinus, I. hexagonus, and two Ixodes spp. Ixodes hexagonus were collected from northern white-breasted hedgehogs (Erinaceus roumanicus), females belonging to Ixodes spp. were collected from red fox (Vulpes vulpes) and nymphs from European badger (Meles meles). Ixodes hexagonus and the Ixodes spp. were identified morphologically and molecularly based on sequences of fragments of two mitochondrial genes, COI and 16S rRNA. Molecular analysis of Ixodes spp. confirmed the identity of Ixodes kaiseri Arthur, 1957 and I. canisuga (Johnston, 1849). Sequence analyses show that the I. kaiseri isolate from Slovakia is identical to I. kaiseri isolates from Romania, Poland, Germany, Turkey, and Croatia. We demonstrate for the first time the presence of I. kaiseri in Slovakia using both morphological and molecular methods.
La dispersion urbaine au Brésil, à l’échelle du système de villes et des agglomérations
Authors: Chatel Cathy , Encarnação Beltrão Sposito Maria
Published: April 2023

La base de données Geopolis permet de comparer les indicateurs relatifs aux agglomérations urbaines dans le monde. Brasipolis reprend la méthode Geopolis pour le Brésil. À partir d’indicateurs tels que la population, la superficie et la densité des agglomérations urbaines, nous questionnons le concept de « dispersion urbaine » employé dans les études urbaines en portugais, en espagnol et en italien pour décrire l’«  urban sprawl  » (étalement urbain). L’étalement urbain au Brésil n’est pas aussi marqué que dans d’autres pays. La dispersion se manifeste par une déconcentration de la population dans un système urbain maillé d’agglomérations de taille moyenne.
Des objets géographiques non identifiés aux agglomérations forcloses en Afrique
Authors: Moriconi-Ébrard François , San Emeterio José Luis , Gazel Hervé
Published: April 2023

La base de données régionale Africapolis, issue de la base Geopolis, recense systématiquement, localise et estime la population des agglomérations de plus de 10000 habitants en Afrique. Certaines d’entre elles ont atteint une taille considérable sans pour autant être reconnues formellement comme « urbaines ». Présentées dans un précédent article, comme des objets géographiques non identifiés (OGNI), cette notion est ici formalisée à partir du concept de « forclusion ». En psychanalyse ou en droit, une chose est dite « forclose » – littéralement : enfermée dehors – lorsqu’elle ne dispose d’aucune représentation à l’intérieur d’un champ symbolique ou théorique. L’article analyse donc les principaux facteurs qui pourraient expliquer l’absence de représentation de ces agglomérations : construction des définitions statistiques nationales officielles, méthodologie des algorithmes de télédétection automatique, avatar des stratégies nationales et internationales de développement, contradictions théoriques avec les processus envisagés classiquement dans l’émergence de l’urbanisation.
Économie et politique : retour des États ou des nations ?
Authors: Ragot Xavier
Published: April 2023

C’est une erreur de voir dans la mondialisation un phénomène purement économique. Sa crise est au contraire d’ordre politique. Elle procède de l’affirmation de la puissance des États et de l’absence de correction des déséquilibres sociaux au sein des nations. L’enjeu politique central de la recomposition de la mondialisation est alors de dépasser la simple logique de puissance étatique pour répondre aux enjeux sociaux propres aux nations.
Les strates historiques de la « nation » et leurs recompositions contemporaines
Authors: Escudier Alexandre , Baechler Jean
Published: April 2023

Contre une approche abstraite ou identitaire, Alexandre Escudier entreprend une généalogie historique et conceptuelle de la nation en examinant les différentes étapes de sa constitution sociale et politique. C’est uniquement à partir de cette analyse concrète des institutions et des mécanismes de régulation sociale qu’il est possible de comprendre la crise actuelle des nations démocratiques.
La nation, soleil noir de la modernité
Authors: Branthôme Thomas
Published: April 2023

Contre une idée reçue, Thomas Branthôme démontre qu’historiquement la nation s’est construite contre le nationalisme identitaire. Elle a au contraire été le lieu d’une dynamique de démocratisation du pouvoir politique inséparable de l’histoire de la gauche française et européenne.
Croissance, crises et régulation du capitalisme
Authors: Aglietta Michel , Bruel Hugo , Lojkine Ulysse
Published: April 2023

Le capitalisme mondialisé est une économie de rentes : financière, digitale, territoriale. Cette situation d’instabilité explique la crise sociale et économique actuelle. Ce n’est donc que par une redéfinition des rapports de production et des institutions qu’il sera possible de parvenir à un modèle de croissance juste et durable.
Taxer les entreprises multinationales au XXI e siècle
Authors: Zucman Gabriel , Carraud Cyprien
Published: April 2023

Aujourd’hui, 40% des profits des multinationales sont délocalisés chaque année vers des paradis fiscaux. Gabriel Zucman montre qu’il est néanmoins possible d’imposer les compagnies multinationales – même dans un monde globalisé, et en l’absence de coordination politique internationale. Ainsi pourrait-on accéder à un système plus juste, et à une mondialisation plus sûre.
Lecture
Authors: Bet Marion
Published: April 2023

Dans son Petit manuel de justice climatique à l’usage des citoyens, James Boyce propose l’instauration d’une taxe-carbone, redistribuée sous la forme d’une rente universelle. Un tel projet pourrait concilier de manière décisive une écologie sérieuse et une politique sociale ambitieuse.