bluuebunny/crossref_metadata_2025 huggingface dataset:
The Tourist/Researcher Nexus: Investigating Social Justice Projects in Cambodia, Myanmar and Laos
Authors: Bell Claudia
Published: November 2019

Cambodia, Myanmar and Laos are destinations growing in popularity. All three countries are poor, with a context of recent or current conflict. Tourism is regarded as a potential saviour: a source of foreign money, whilst enhancing global awareness of each nation. Whilst tourism is largely government managed, diverse NGOs work to ameliorate conditions of the poor. There are also private social entrepreneurs running operations to upskill disadvantaged people. This paper explores a range of grassroots ventures. Tourists are the customers for most of these enterprises; so how does the academic researcher considering these spaces as case studies, differ from tourists?Fieldwork took place on three visits, 2017-2019. Initiatives included artisan and craft projects, food producers, restaurants, and eco-tourism. For social entrepreneurs running these, theire schema is responsible, grassroots development, to a social justice agenda. Many tourists consciously seek such sites. In this way, the touristic practice resembles the researcher praxis. This researcher, like any visitor, located such enterprises via websites, travel blogs, and in the field. Most functioned as charities or modest businesses. Ethically, and out of courtesy as well as desire, the researcher also purchased goods and services from each enterprise, exactly as tourists do.
Ser docente: inspiración, pasión y perseverancia
Authors: Sánchez Mendiola Melchor
Published: November 2019

El tiempo pasa vertiginosamente y cuando nos damos cuenta ya estamos a fin de año y en el cierre de algunos ciclos. La Revista Digital Universitaria (RDU) pasó de la Dirección General de Cómputo y de Tecnologías de Información y Comunicación (DGTIC) de la Universidad Nacional Autónoma de México (UNAM) a la Coordinación de Desarrollo Educativo e Innovación Curricular (CODEIC) de la misma institución, en el primer semestre de 2017.
Una experiencia de formación: la Educación basada en evidencias
Authors: Campillo Labrandero Magda , Pompa Mansilla Maura , Hernández Carrillo Flora Beatriz , Sánchez Mendiola Melchor
Published: November 2019

La Educación basada en evidencias (ebe) busca que los docentes y otros profesionales involucrados en la educación informen sus decisiones y acciones con los hallazgos encontrados en la literatura científica publicada en el campo educativo. En el presente artículo se comparte la experiencia de los cursos ebe, que desde 2016 ofrece la Coordinación de Desarrollo Educativo e Innovación Curricular (codeic) a los docentes de la Universidad Nacional Autónoma de México (unam). También se describe cómo se conformó la comunidad de práctica cebe (Comunidad de Educación Basada en Evidencias) así como las actividades que realizan sus miembros. Tanto los cursos ebe como la cebe son experiencias de formación docente novedosas que han vinculado el arte de la enseñanza con los avances científicos en el campo de estudio de la educación.
TEACHING ENGLISH VOCABULARY USING PICTURE IN EIGHTH GRADE OF JUNIOR HIGH SCHOOL
Authors: Winita Restu Anggi , Rasyida Fairuz Sopiya
Published: November 2019

This research focused with teaching English vocabulary using picture in eight grade of junior high school. This research explores the implementation of English vocabulary and to find out the score improvement in using picture in learning process. The objective of this research is to find out the effectiveness of picture in improving students’ vocabulary. Data collection technique focus on pretest and posttest. Picture is a good media to make everything like real and can visualize to the lesson environtment.  The means score of pretest was 42.33 and the posttest get improve to 76.50. It could also be concuded that teaching English vocabulary using picture was effective media to improve students’ vocabulary.
IMPROVING STUDENTS’ READING COMPREHENSION OF DESCRIPTIVE TEXT USING CIRC TECHNIQUE
Authors: Anwar Syamsul , Januar Ruanda
Published: November 2019

This research become performed in MA Al-Mukhtariyah Mande West Bandung. The objective of this research is used to investigate the implementation of CIRC technique in improving the students reading comprehension of descriptive text. The method used in this research was quantitative method. The design of the research was pre-experimental design. There are three steps involving pre-experimental design. The first step is the administration of pre-test measuring the dependent variable. The second step is the application of the experimental treatment (independent variable) to the subjects, and the final step is the administration of a posttest measuring the dependent variable again. It has seven times of conducting data, namely pretest, posttest, and five times treatments. Based on the result of pre-test, we observed that students’ reading comprehension is below average, the mean score of pre-test is 42.79. After the implementation of CIRC technique in every meetings, the students’ reading comprehension had been getting better, it is able to be seen in average of the mean score of post-test becam 73.82. It is able to be concluded that CIRC techniqiue can improve students’ reading comprehension. Keywords:        Reading Comprehension, Descriptive Text, CIRC Technique
An Analysis of Idioms in “Guardian of the Galaxy Vol.2” Movie
Authors: Rosalia Sasa , Noerazizah Siti , Anggraeni Anita
Published: November 2019

The aims of this research is to find out the types of idiom which is used in Guardian of Galaxy Vol.2 Movie and type of idiom which mostly presented in the movie. In this research, the writer used qualitative method. In collecting data, the writer used a movie script which downloaded from the internet and the writer analyzed it based on O’Dell & McCarthy theory. O’Dell & McCarthy argued that idioms are divided into 6 types; simile, binomials, proverbs, euphemism, clichès and fixed statement, and other language. The result of the analyzed data showed that from 6 types of idiom, only three types of idioms appear in this movie, which are; simile (4), binomial (6), and fixed statement (9). Keyword: Idiom, Movie
THE USE FLASH CARD TO IMPROVE YOUNG LEARNER’S VOCABULARY MASTERY
Authors: Andriyadi Andriyadi , Irawan Apep Nana
Published: November 2019

This paper describes the using of flash cards to improve mastery of the vocabulary of young learners. The purpose of this paper is to illustrate the effectiveness and ineffectiveness of flash cards used in teaching vocabulary for young learners. Researchers conducted research using quantitative methods to elementary school children in SDN 2 Cijenuk. The study was conducted in four steps: first planning action, second implementation, and third observation, and last reflection. Data were collected using quantitative data collection techniques. The results showed that the use of Flashcards can improve the mastery of children's vocabulary. This can be seen from the average value of the test that increased from 71.50 on the previous test to 85.55 in the post-test. Using a flash card can make students pay attention to the lessons well and not make students bored, also makes the learning atmosphere more controllable. Keywords:  Vocabulary Mastery, Flash Card, Young Learner
AN ANALYSIS OF DONAL J.TRUMPS REMARKS ”MY FELLOW AMERICANS” USING INTERPERSONAL METAFUNCTION
Authors: Sari Mayang , Ariani Dian Meta
Published: November 2019

The aims of this reasearch is analyzing President Donal J.Trump statement in weekly address on www.whitehouse.gov entitle “My fellow american” based on systemic functional grammar. The writers focused on interpersonal metafunction which consist of mood and speech functions. The method in this research used qualitative analysis method. The data were analyzed using mood structure analysis by M.A.K Haliday. The text entitled My Fellow American the statement by President Donal J.Trump Remarks is categorized into the text which uses declarative mood type the most (69,2%) which indicates the position o the speaker provider of information and the listeners as the recepeint of information. The clauses in the text are said by temporal deicticity or finite tense the most (89%), while the modality deicticity only appears a  little (5%) which indicates that the speaker has no right to persuade the listeners because the genre of the text is narrative which functions only to telling the listeners.There are only two speech functions found in the transcipt of President Donal J.Trump are statment and question. Statement as mostly appeared in the text which reaches precentage 75% whereas question only reaches percentage 25%. So it can be concluded that speech function used in the transcipt is statement with function to give information.
IMPROVING STUDENT’S VOCABULARY MASTERY THROUGH COOPERATIVE SCRIPT ON DESCRIPTIVE TEXT
Authors: Aisyah Nenis Siti , Hidayatur Rahma Nur Afni , Yugafiati Rasi
Published: November 2019

Abstract This study is revealed based on  the observation on the tenth grade of X HT 1 Sangkuriang 2 Vocational High School.  The subjects of this study were consisted of 31 students. This study was aimed to improve the students’ vocabulary mastery using Cooperative Script Method. The research design was Classroom Action Research (CAR) which following from Kemmis and Taggart model. It is used to obtain the results of quantitative and qualitative data using 2 cycles described through planning, action, observation, and reflection on each cycle. The result of the study showed that there was a development on the student’s vocabulary mastery. It could be seen from the result of the test. The Minimum Mastery Criteria (KKM) of English lesson was 70.  The students mean score in the pre test was 50,  in the first post test the mean score was 65, and in the second post test the mean score was 85. In addition there were 2 students (6,4%) who passed KKM on pre test. In the first pretest there were 9 students (29,03%) who passed KKM. In the second pretest there were 29 students (93,55%) who passed KKM. Then, from the result of field notes and interview it showed the positive responses from the students. The students can be more active and improve their ideas. The researcher conclude that Cooperative Script method could improve student’s vocabulary mastery. Keywords:  Vocabulary, Cooperative Script, Descriptive Text, CAR
THE IMPLEMENTATION OF PROJECT BASED LEARNING TO IMPROVE STUDENT’S SPEAKING SKILL
Authors: Haerani Rini , Jatiraga Rahayu
Published: November 2019

The background of the experiment was to find out whether the influence of project based learning in improving the speaking skill among eighth grade students of SMPN 3 Padalarang in the academic year of 2018/2019. The method of this study was quantitative technique and the one shot case study design conducted in single class. The researcher conducted the tests before (pre-test) and after (post-test). The research effect display the improvements in speaking ability. The score of pre-test was 63.87, and the post-test was 76.29. Based on students’ attitudes toward the utilized Project based learning, the discovery indicated that most of students rated the use of technique moderately positive. Nearly all of students agreed that project based learning is capabel to improve their speaking mastery ,accumulate their vocabulary mastery,develop their creative thinking, and increase their presentation skill. issue of this study showed that by applying project based learning on learning English can to increase students’speaking skill.Keywords: project based learning, speaking skill
GETTING TO GRIPS WITH THE LARGER PATTERNS IN THE REPORT TEXT
Authors: Rahmah Syarah Nur , Kareviati Evie
Published: November 2019

This research is aimed to know about what larger patterns are used in the report text and what is the role of larger patterns used for the reader. The researcher found that the report text about Australian senator hit with egg after blaming imigration for mosque attack (Karasz, 2019) used claim-counterclaim patterns.The role of claim-counterclaim patterns in that report text is to make readers easy to understand the text, as the reader will know who is the one who was claimed at the beginning as an anti-imigration person, and why he hit a teenager, and what is the reason the teenager smashed him. The researcher suggests for the futher researcher to use other more interesting sources to find more the larger patterns and to knowabout the role of the patterns.Keywords: Larger patterns, report text
The Use Superordinate Concept in The Meaning of speech
Authors: Perkasa Dicky Widiya , Santoso Iman
Published: November 2019

Words have been existed since hundreds of years ago the implicit meaning of a words can indicate an expression of someone Through human words can communicate with various kinds of meanings in their conversation, in the concept of writing the researcher will explain a concept of superordinate which as a form of word level the highest which has the earliest meaning of each word, The good thing that can be learned in this superordinate concept is that the meaning of the word will not become complicated, for example "The fish is very ferocious", then what fish does it mean that might be sharks or dolphins, in fact sharks are wild fish, but fish dolphins are not fierce, from which the superordinate has not been able to represent the above words so that in the form of the next two concepts which further pursing the word "fish" above into "The shark is very ferocious" the shark refer to the Basic concept and then it can be more specific from Subordinate to be like this "The white shark is very fierce" (white shark) is subordinate. In another case why the researcher takes the concept from this superordinate is to explain that a meaning in the word has owned level and then the words will not always have the same meaning in delivering their purpose, regardless of the daily conversation pretty much people used "Basic and Subordinate" due the meaning is more referring and precise.
STRATEGIC PLANNING EKSPANSI KAPASITAS PRODUKSI SEMEN DARI 4 JUTA TPY MENJADI 7 JUTA TPY DI DEPARTEMEN PENAMBANGAN PADA PABRIK SEMEN PT.”X”
Authors: T. Dimyati Tjutju , Setyo Oetomo Dedy
Published: November 2019

Keputusan Top Manajemen untuk meningkatkan kapasitas produksi dari 4 juta TPY menjadi 7 Juta TPY menyebabkan perubahan volume bahan baku dan peralatan yang di perlukan untuk mencapai target produksi yang baru. Dukungan ketersediaan bahan baku utama baik dari segi jumlah maupun kualitas merupakan hal yang sangat penting agar aktivitas produksi semen berlangsung sesuai rencana. Selain bahan baku, penyediaan peralatan produksi di departement penambangan juga harus direncanakan agar mampu mengejar target produksi secara efektif dan efisien. Hal ini disebabkan adanya perbedaan antara waktu produksi pada departement raw material preparation, departement clinker burning dan departement finished product dengan waktu produksi di departemen penambangan. Kajian ini dilakukan untuk mendapatkan bahan baku yang diperlukan dengan peningkatan kapasitas produksi tersebut. Selain itu, dilakukan juga perhitungan untuk memperkirakan kebutuhan peralatan tambahan serta biaya yang perlu disediakan. Metode yang digunakan adalah simulasi perhitungan kebutuhan bahan baku dan peralatan dari masing masing proses yang ada di skematik proses pembuatan semen PCC di PT.’X”. Hasil perhitungan memperlihatkan bahwa selisih penambahan limestone adalah 2,960 ton, claystone 2,000 ton, silica 88 ton, dan iron ore adalah 62 ton. Kebutuhan alat penambangan bertambah menjadi hampir dua kali lipat, sedangkan biaya yang diperlukan adalah USD 24,776,786.
The Role of Communication in Behavioral Freedom During the Coordination Process of An Organization
Authors: Pujiati Pujiati
Published: November 2019

Communication is the means to clarify expectations and to coordinate the tasks responsibility that allow the people to achieve the objectives of the organization to be more efficient and effective. Communication is the exchange of information between the sender and the receiver in which the process of information and the meaning of the message is delivered well. Most of the tasks responsibility that is done by a team works on interdependent and mutually connected to each other of the organization’s member. Therefore, the effectiveness of communication plays an important role in determining whether there is a profit or loss in the process of communication. An organization is a group of people who work in interdependence through communication. In organizational activity, there is the process of delivering and receiving the messages to run the organization’s performance. It means that the role of communication is very influential in behavioral freedom during the coordination process of an organization. This research deals with the notion of communication, communication function, model of communication, communication barriers, and how to improve the communication process. The purpose of this research was to know and to describe the role of communication in behavioral freedom during the coordination process of an organization. This research was a descriptive research. The results of this research showed that the development behavioral freedom during the coordination process of an organization needed to be dynamic during the working performance to achieve the goal; one of them was to understand and perform the communication process properly. Some of the obstacles in communication, according to Robbins and Judge, were the process of filtering, selective perception, information overload, emotions, language, silence, communication apprehension, gender differences, etc. Those obstacles could be solved by interpersonal communication, strategies and skills to communicate described in this paper, so that the organization could run well reaching the desired goal.
Correlation of Sensation Seeking with Entrepreneurship: Study on Fresh Graduate Universitas Syiah Kuala
Authors: Mirza Rahmad , Aprilia Eka Dian
Published: November 2019

Nowadays, getting a job is very difficult, there is no guarantee for a graduate to get a job. One of the alternatives is to become an entrepreneur. To become an entrepreneur needs self-confidence, responsibility, decision making skill, perseverance and risk taking which are in accordance with the dimensions of sensation seeking i.e. thrill and adventure seeking, experience seeking, disinhibition, and boredom susceptibility. This study aimed to understand the sensation seeking and entrepreneurship of the fresh graduates in The University of Syiah Kuala. The samples were 120 fresh graduates who were selected with quota sampling technique. There were two instruments used, Brief Sensation Seeking adaptation Scale (BSSS-8) by Hoyle et al (2002) consisting of 8 items and an Entrepreneurship Scale based on Koh’s theory (1996) consisting of 24 items. Data analysis result using Pearson correlation technique showed a correlation coefficient of (r) 0,714 with p value = 0,000 (p < 0,05). The proposed hypothesis was confirmed therefore it can be concluded that there was a positive and significant correlation between sensation seeking and entrepreneurship of the fresh graduates in The Universitas Syiah Kuala.
The Influence of Peer Social Support to Student with Special Needs in Elementary Schools Inclusion
Authors: Pitaloka Mega Ayu , Faizah Faizah
Published: November 2019

This study aimed to determine the effect of value social support learning through audio visual media to peer social support in Student with Special Needs in Elementary School Inclusion. The research design used quasi experiment with one group pretest-posttest design. Participants in this study were students in one of  elementary school inclusion Malang grade 3, 4 and 5. The research instrument used the scale of social support peers referring to Sarafino and Smith (2011) and value social support learning through audio visual media that is social support video. Data analysis using IBM SPSS statistics 23.0 software with t-test using paired sample t-test. Finding showed that Value learning through social support video effects to peer social support in student with Special Needs in Elementary School Inclusion, with significance of 0.001 (p <0.05).
Guidelines for Performing Nuclear Magnetic Resonance Imaging Examinations in Patients with Cardiac Electronic Devices
Authors: Vitor Moraes Junior Antonio , Pereira Valdigem Bruno , Monteiro Boya Barcelos Cecilia , Salgado de Melo Celso , Lopes Pereira Wilson , Muniz Leão Filho Hilton , Antônio Rocha Mello Marco , Antônio F Fonseca Junior Cyro , Eduardo Nunes Mariz Fernando , Rodrigues de Abreu Marcelo , Prando Cardia Patrícia , Roberto Vieira de Andrade Paulo , Kodlulovich Renha Simone , dal Forno Alexander , Luiz Buchele D´Avila Andre , Alkmin Teixeira Ricardo , Silva de Andrade Veridiana
Published: November 2019

It is estimated that up to 75% of patients with cardiac implantable electronic devices (CIEDs) will have an indication for nuclear magnetic resonance imaging (MRI) throughout their lives. Th is population has been historically excluded from the list of patients considered eligible for this examination due to the characteristics of the devices.
The Possibilities of Using Ecological Liquids in Tribological Gliding Systems with a Selected Surface Created by the Radial Welding Technology
Authors: Tóth František , Fürstenzeller Adam , Rusnák Juraj , Bošanský Miroslav , Kadnár Milan
Published: November 2019

Presented paper deals with the issue of lubricating tribological systems formed by a double pair operating under mixed conditions of mixed friction before and after experimental tests, which were conducted in accordance with the selected methodology using Tribotestor M‘06 test machine. The lubricating media included ecological oils Plantohyd 46 S by Fuchs and EAL Hydraulic 46 manufactured by the Mobil company. Applied ecological oils can be used in agricultural mobile machines as a replacement for conventional lubricants. The tests were conducted on designated material double pairs. The shaft was made of steel 16MnCr5. The second observed friction element in terms of glide angle test was a steel plate made of S235JR, gliding surface of which was produced utilizing flame powder coating technology. The results were statistically processed and are presented in the form of graphs, tables and figures.
Feasibility Study of Improving the Transport Performance by Means of Screw Conveyors with Rotary Casings
Authors: Rohatynskyi Roman , Gevko Ivan , Diachun Andrii , Lyashuk Oleg , Skyba Olena , Melnychuk Andrii
Published: November 2019

Paper presents feasibility study for verification of the hypothesis of improving the productivity of reload operations using screw conveyors with rotary casings. For this purpose, an experimental installation was developed and experimental studies were conducted. Research results fully confirmed the hypothesis. On the basis of a feasibility study of casing rotation in screw conveyors, the conveyor performance increased by 24%, with the conveyor capacity thereby increased by 4.5%. Due to the application of rational parameters of the screw conveyor with a rotary casing, overall economic factor was improved by more than 10%. To achieve the economic efficiency of reload operations using screw conveyors with rotary casings, the rotational frequency of the casing should range from 460 to 620 rpm.
Getting ready for fieldwork education! – Creation of a skill profile for fieldwork educators in occupational therapy / Fit für die Praktikumsanleitung? – Erstellung eines Anforderungsprofils für ergotherapeutische Praxislehrende
Authors: Galler Elfriede , Ruckser-Scherb Renate
Published: November 2019

Owing to ongoing changes in the working world and the resulting changing requirements of university graduates, requirements for teachers are continuously changing. Although this is currently being taken into account at universities, there is a need to take action in the area of fieldwork education.

The aim was to create a skill profile for fieldwork educators in occupational therapy, thus providing a basis for fieldwork educators, universities, professional associations, and employers. This reflects on existing measures and generates new measures to facilitate quality improvement in the area of fieldwork education.

Requirements were evaluated in two focus groups with a total of 14 practical training experts. Data were analysed within the scope of a qualitative content analysis and summarized in one profile.

A total of 18 professional, methodical, social, and personal requirements were identified. Fieldwork educators are able to organise, take responsibility, have expertise, and prepare contents adapted to the needs of individual students. They guide, supervise, give feedback to students in a formative way, thereby assessing and supporting their personal development. Moreover, as communicators, they have a stable personality, are open for further development, flexible, and reflective.

In order to meet these requirements, fieldwork educators must be fully committed. Moreover, the professional association needs to create a role model and provide task-specific cross-university training. It also requires the support of universities who are called upon to increase networking and communication with all parties involved and the support of the employers who need to provide additional time resources.
Frontal assault versus incremental change: A comparison of collective bargaining in Portugal and the Netherlands
Authors: Hijzen Alexander , Martins Pedro S. , Parlevliet Jante
Published: November 2019

Collective bargaining has come under renewed scrutiny, especially in Southern European countries, which rely predominantly on sectoral bargaining supported by administrative extensions of collective agreements. Following the global financial crisis, some of these countries have implemented substantial reforms in the context of adjustment programmes, seen by some as a ‘frontal assault’ on collective bargaining. This paper compares the recent top-down reforms in Portugal with the more gradual evolution of the system in the Netherlands. While the Dutch bargaining system shares many of the key features that characterise the Portuguese system, it has shown a much greater ability to adjust to new challenges through concerted social dialogue. This paper shows that the recent reforms in Portugal have brought the system more in line with Dutch practices, including in relation to the degree of flexibility in sectoral collective agreements at the worker and firm levels, the criteria for administrative extensions, and the application of retro- and ultra-activity. However, it remains to be seen to what extent the top-down approach taken in Portugal will change bargaining practices, and importantly, the quality of industrial relations.
Pollen Analysis of Honey from Borana Zone of Southern Ethiopia
Authors: Bareke Tura , Addi Admassu
Published: November 2019

Nineteen samples of honey were collected from different localities of the Borana Zone and examined to identify the botanical origin of honey through honey pollen analysis. From nineteen honey samples, sixteen were identified as monofloral honeys. Twentyeight plant species were identified as honey source plants and the identified plant species belonged to fourteen plant families. Out of twenty-eight bee plant species, 17.9% of them were found in the Fabaceae family followed by Asteraceae and Lamiaceae, each of them accounting for 14.3% of all honey plants species found in the samples. The Shannon-Wiener diversity index (H) showed that high diversity of plant species was found in eleven honey samples with a range of 1.07 (Bule Hora site 1) to 1.81 (Yabello site 2) on the basis of honey pollen analysis. Eight honey samples had lower diversity index values, ranging from 0 (Arero site 2 and Bule Hora site 3) to 0.84 (Gelana site1), which suggests the honey was obtained from a few dominant plant species. Accordingly, Guizotia scabra, Haplocoelum foliolosum, Plectranthus assurgens, Terminalia brownii, Sesamum indicum, Satureja paradoxa, Croton macrostachyus and Acacia brevispica were the major monofloral honeys produced from the area. This indicates that there is a huge potential for the production of monofloral honey. Since monofloral honey has a good market value and is preferred by consumers, the involvement of investors is recommended.
An Overview of Disease Burden, Mechanism, Traditional and Non-traditional Management of Type 2 Diabetes
Authors: Akram Hammad , Aslam Fauzia
Published: November 2019

Diabetes is a major global health problem leading to high morbidity, mortality, and economic burden. Diabetes is connected to complex social, environmental, and behavioral factors and requires multisectoral evidence-based strategies to reduce its incidence and prevalence. Here we attempt to connect existing diabetes data with the underlying mechanism of the disease, while touching disease processes and traditional management approaches for diabetes and its complications. The major objective of this manuscript is to examine the effect of nontraditional treatment modalities, e.g. non-pharmaceutical interventions, supplements, alternative and integrative therapies etc., on diabetes. We performed an extensive literature search and review using electronic databases (PubMed and Google Scholar) to examine recent and historical diabetes statistics, the underlying mechanism of the disease, traditional treatments, remission possibility, and finally, the role of alternative therapies and supplements in its management. We found that there is no sufficient evidence to make most of the alternative therapies the first line of management and prevention approach for diabetes. Long-term and large-scale studies are needed to evaluate the safety and efficacy of alternative medicine. We feel that this review could urge other health researchers to plan comprehensive studies to examine the role of alternative or newly-identified therapies in diabetes. Also, this information can be useful for diverse health professionals and policymakers in developing and implementing evidence-based strategies.
Immune Thrombocytopenia in an Adolescent with Hashimoto’s Thyroiditis – Case Report
Authors: Kelemen Izabella , Papp Zsuzsanna Erzsébet , Horváth Mária Adrienne
Published: November 2019

Introduction: In childhood, thrombocytopenia caused by transient antibody-mediated thrombocyte destruction is most frequently diagnosed as immune thrombocytopenic purpura (ITP). We report the case of a girl with ITP associated with autoimmune thyroiditis.

Case presentation: A 11-year-old female patient with Hashimoto’s thyroiditis presented with clinical signs of petechiae and ecchymoses on the extremities. Laboratory tests showed remarkable thrombocytopenia with a platelet count of 44,500/μL, hence she was referred to a hematologic consultation. The peripheral blood smear showed normal size platelets in very low range. The bone marrow examination exposed hyperplasia of the megakaryocyte series with outwardly morphologic abnormalities. The patient was diagnosed with ITP, and her first-line treatment was pulsed steroid and immunoglobulin therapy. The thrombocytopenia was refractory to these first-line medications. After 6 months of corticotherapy and a period of severe menorrhagia, azathioprine immunosupression was initiated as a second-line treatment. Her platelet count rapidly increased, and the evolution was good, without bleeding complications.

Conclusion: In case of a medical history of autoimmune diseases and treatment-resistant ITP, attention must be focused on detecting coexisting autoimmune diseases and adjusting the treatment in accordance with the chronic evolution of the disease.
A Genomic Approach to Characterize the Vulnerable Patient – a Clinical Update
Authors: Szabó Evelin , Parajkó Zsolt , Opincariu Diana , Chițu Monica , Raț Nóra , Benedek Imre
Published: November 2019

Atherosclerosis is the elemental precondition for any cardiovascular disease and the predominant cause of ischemic heart disease that often leads to myocardial infarction. Systemic risk factors play an important role in the starting and progression of atherosclerosis. The complexity of the disease is caused by its multifactorial origin. Besides the traditional risk factors, genetic predisposition is also a strong risk factor. Many studies have intensively researched cardioprotective drugs, which can relieve myocardial ischemia and reperfusion injury, thereby reducing infarct size. A better understanding of abnormal epigenetic pathways in the myocardial pathology may result in new treatment options. Individualized therapy based on genome sequencing is important for an effective future medical treatment. Studies based on multiomics help to better understand the pathophysiological mechanism of several diseases at a molecular level. Epigenomic, transcriptomic, proteomic, and metabolomic research may be essential in detecting the pathological phenotype of myocardial ischemia and ischemic heart failure.
Coronary Artery Aneurysms Due to Kawasaki Disease – a Rare Cause of Acute Myocardial Infarction
Authors: Cîrneală Ioana , Păsăroiu Dan , Kovács István , Benedek Imre , Togănel Rodica
Published: November 2019

Kawasaki disease, also known as Kawasaki syndrome or mucocutaneous lymph node syndrome, is a pathology that causes inflammation in the walls of medium-sized arteries, with symptoms such as fever, lymphadenopathy, rash, and erythema of the eyes, lips, nose, palms, and feet. The cause is unknown, although clinical features strongly suggest an infectious etiology. We present the case of a 53-year-old woman, known with Kawasaki disease since childhood, with different associated pathologies, who presented with acute inferior ST elevation myocardial infarction.
Predictors of Left Ventricular Remodeling Post Acute Myocardial Infarction. Protocol for a Clinical Study
Authors: Cîrneală Ioana , Opincariu Diana , Kovács István , Chițu Monica , Benedek Imre
Published: November 2019

Heart failure is a clinical syndrome that appears as a consequence of a structural disease, and the most common cause of left ventricular systolic dysfunction results from myocardial ischemia. Cardiac remodeling and neuroendocrine activation are the major compensatory mechanisms in heart failure. The main objective of the study is to identify the association between serum biomarkers illustrating the extent of myocardial necrosis (highly sensitive troponin as-says), left ventricular dysfunction (NT-proBNP), and systemic inflammatory response (illustrated via serum levels of hsCRP and interleukins) during the acute phase of a myocardial infarction, and the left ventricular remodeling process at 6 months following the acute event, quantified via speckle tracking echocardiography. The study will include 400 patients diagnosed with acute myocardial infarction without signs and symptoms of heart failure at the time of enrollment that will undergo a complex clinical examination and speckle tracking echocardiography. Serum samples from the peripheral blood will be collected in order to determine the inflammatory serum biomarkers. After 6 months, patients will be divided into 2 groups according to the development of ventricular remodeling, quantified by speckle tracking echocardiography: group 1 will consist of patients with a remodeling index lower than 15%, and group 2 will consist of patients with a remodeling index higher than 15%. All clinical and imaging data obtained at the baseline will be compared between these two groups in order to determine the features associated with a higher risk of deleterious ventricular remodeling and heart failure.
Recycling of Cerium and Lanthanum from Glass Polishing Sludge
Authors: Lee Ching-Hwa , Lo Yu-Chien , Sandagdorj Nyamdorj , Gankhuyag Enkhsaikhan , Popuri Srinivasa Rao , Hung Chi-En
Published: November 2019

To examine the efficiency of La and Ce recycling processes from the sludge, two major methods were used, namely leaching and precipitation. The findings suggest that 12% of La and 24.2% of Ce were contained in the sludge. The sludge was leached in an optimum condition of 6N HCl at a temperature of 70°C with a 3g/50 mL solid/liquid ratio for 3 h to obtain a 100% leaching recovery of La and Ce. After pH adjustment of the obtained La and Ce optimum leaching solution to 6 with NH4OH and a simultaneous addition of H2O2 in a ratio of 1:1, Ce precipitated out with 65.9% recovery. On the other hand, La was not precipitated. The results obtained in this study reveal that leaching and pH adjustment method could be used to recover the valuable REE of La and Ce from glass polishing sludge in order to reach the goals of resource recycling.
The Use of Tuned Mass Dampers for Reducing Structural Vulnerabilities During the Side Movements of Buildings with Reinforced Concrete Frames
Authors: Rece Laurentiu , Ezzaki Naima , Stoica Daniel , Jeflea Victor Florin
Published: November 2019

The present article aims to point out, with the help of a comparative research, the efficiency of tuned mass dampers, modern variants of consolidation ensuring seismic structural safety, used for buildings with a reinforced concrete structure, designed and produced according to the new codes. Case studies were based on structural computations in the linear elastic field using the ETABS program.
Familial Hypercholesterolemia with Tendinous Xanthomas and Achilles Tendinitis – A Forgotten Dermato-Rheumatologic Association
Authors: Sahu Puspanjuli , Mohanan Saritha , Udayshankar Carounanidy , Sinhasan Sankappa P. , Bhat Ramachandra V.
Published: November 2019

Familial hypercholesterolemia (FH) is a disorder of lipoprotein metabolism with dermatological and rhematological manifestations. Tendinous xanthomata (TX) are a hallmark of this disease. They are associated with recurrent tendinitis and tendon damage, an aspect of the clinical presentation, which is not well-known among dermatologists. We report two cases of heterozygous familial hypercholesterolemia, where the patients started developing tendinous xanthomata early in their life, with progressive increase in the number and size of lesions. However, they presented late, only when the recurrent attacks of tendinitis became severe. We present these cases to highlight the rheumatologic features, which may be the first symptom of heterozygous familial hypercholesterolemia.
Early-Onset Neonatal Sepsis
Authors: Jovicic Marija , Folic Marko , Jankovic Slobodan
Published: November 2019

Despite the great progress made in neonatal and perinatal medicine over the last couple of decades, sepsis remains one of the main causes of morbidity and mortality. Sepsis in pediatric population was defined at the Pediatric Sepsis Consensus Conference in 2005. There is still no consensus on the definition of neonatal sepsis. Neonatal sepsis is a sepsis that occurs in the neonatal period. According to the time of occurrence, neonatal sepsis can be of early onset, when it occurs within the first 72 hours of birth and results from vertical transmission, and of late onset, in which the source of infection is found most often in the environment and occurs after the third day of life. The most common causes of early-onset sepsis are Group B Streptococcus (GBS) and E. coli. Risk factors can be mother-related and newborn-related. Clinical symptoms and signs of sepsis are quite unspecific. The dysfunction of different organs may imitate sepsis. On the other hand, infectious and non-infectious factors may exist simultaneously. The start of the antimicrobial therapy in any newborn with suspected sepsis should not be delayed. Pentoxifylline may have potential benefits in preterm newborns with sepsis. The only proven intervention that has been shown to reduce the risk of early-onset neonatal sepsis is intrapartum intravenous antibiotic administration to prevent GBS infection. It is still a great challenge to discontinue antibiotic treatment in non-infected newborns as soon as possible, because any extended antibiotic use may later be associated with other pathological conditions.
Biochemical and histopathological changes caused by Atorvastatin in Gentamicin treated rats.
Authors: Alzubaidi Fatima Adnan , Hussein Radhwan M. , Mohammed Zainab Sajid , Oubaid Enass Najem
Published: November 2019

Introduction: Gentamicin is a member of antibiotic group (aminoglycosides), it's very effective in the management of many gram negative bacterial infections but its nephrotoxic effect is considered the major limiting factor. The protective role of Atorvastatin against this adverse effect in male rats was investigated in this study. Materials and methods: thirty adult Wistar male rats were included in the study, they were divided into 3 groups randomly with ten rats in each one, rats in group (1) were given normal standard diet and considered as control. Rats in group (2) were given gentamicin in a dose of 100 mg per kg per day, intraperitoneally for four weeks, while rats in group (3) were given gentamicin in a dose of 100 mg per kg per day, intraperitoneally together with atorvastatin 10 mg per kg per day orally for four weeks. Results: treatment with Gentamicin elevated the level of serum urea, cystatin C, creatinine, total oxidant status and tissue malondialdehyde (MDA) significantly while decreased total antioxidant status significantly. Treatment with Atorvastatin decreased the level of serum urea, creatinine, total oxidant status and tissue MDA significantly while increased total antioxidant status significantly. Renal damage in gentamicin treated rats was determined markedly with histopathological studies in the glomeruli and renal tubules. Conclusion: coadministration of statins with gentamicincan can reduce the nephrotoxicity induced by gentamicin treatment.
Cytotoxic Activity of Different Extracts from Brown Marine Macroalgae from the El Jadida Region (Morocco)
Authors: Lasky M , Nmila R , Chibi F , Oualili H Abd Alabas , Idrissi E El Abd Alabas , Abderrazik M Abd Alabas , Rchid H
Published: November 2019

The therapeutic use of extraordinary virtues of algae in healthcare is very ancient and has evolved throughout the history of humanity. However, low or high doses and/or prolonged administration of algae-derived biologically active substances may trigger adverse or even harmful effects such as hemolytic properties.
In this study, hemolytic activities of the brown algae Cystoseira myriophylloides (F/Sargassaceae) from El Jadida coast (Moroccan Atlantic coast) on human erythrocyte were investigated.
The toxicity of chloroform-methanolic, methanolic, chloroformic, isoprpanolic and butanolic extracts and fractions derived from Cystoseira myriophylloides on human erythrocytes was measured by in vitro hemolytic assay.
The results obtained show variable cytotoxicity of C. myriophyloides against the red blood cells. Indeed, the crude extract has a fairly high hemolytic activity that is very marked when the erythrocytes are incubated in the presence of the chloroformic extract. However, the cytotoxic activity is greatly increased in the presence of the butanolic fraction derived by partitioning of the isopropanolic extract. Moreover, the hemolysis activity is dose-dependent and depending on the evolution of incubation time. Thus, these results show that the majority of extracts and fractions of brown macroalgae Cystoseira myriophylloides manifest hemolytic activity.
In Silico Design, Synthesis, and Characterization of Ibuprofen Derivative as Potential Antitumor Agent.
Authors: Ebrahim Al Ani Awatef A. , Hussein Ali Naim , Mohammed Ali Zahraa A. G.
Published: November 2019

Background: Numerous animal studies and clinical trials in cancer have shown that ibuprofen reduces the incidence of and mortality from cancer. Synthesis of novel conjugate of ibuprofen with the 2-phenyl amino pyrimidine derivative (to mimic small molecules kinase inhibitor anticancers) exhibits significant increase, as compared to free ibuprofen, potential to inhibit proliferation of cancer cells.
Methods: The docking study was performed with GOLD software supplied by the Cambridge Crystallographic Data Centre. Thereafter, the chemical synthesis was established. The chemical structures of this study was confirmed by spectral instrumentation; infrared, differential scanning calorimeter thermal analyzer, proton and carbon-13 nuclear magnetic resonance.
Results and Discussions: The docking process was successfully conducted and the chemical synthesis yielded a good per cent. The spectral interpretations show characteristic identification of the target chemical compound.
The Association of ACE Gene polymorphism and Some Biomarkers in Hemodialysis Patients
Authors: Al-Obaidi Maysaa Adil , Al.Saadi Ali Hmood , Al-Amer Rady Wisam Abed
Published: November 2019

The Aim: Chronic kidney disease (CKD) is clarified by constant structural abnormalities, urine abnormalities or damaged excretory renal function indicative of a failure of functional nephrons. One of the treatments for renal fail¬ure is hemodialysis. The aim was assessing the potential association between Angiotensin Converting Enzyme (ACE) gene I/D polymorphism with renal failure and their correlation with some biochemical parameter as Insulin-like Growth Factor 1 (IGF-1) and Symmetric Dimethyl Arginine (SDMA) and kidney function test "urea" and "creatinine" in Iraqi hemodialysis patients.
Materials and Methods: The study was contained 60 hemodialysis patients (30 Male and 30 Female).The control group was 30 healthy subjects (15 Male and 15 Female). The ages of hemodialysis patients and control groups ranged between (11-75 years). The information was taken from a questionnaire which included age, sex, smoking, duration of disease, duration of dialysis, number of dialyses, other disease and family history. Also, BMI, urea, creatinine, IGF-1, and SDMA were measured. After extraction of DNA from white blood cells and carrying out of PCR, characterizing ACE I/D polymorphism by applying an amplification refractory mutation system (ARMS) technique.
Results: The demographic study showed that there were more hemodialysis patients had age ≥ 50 years old (40%)when compared with the control group. The most hemodialysis patients had body mass index (BMI) were 18-24.9 (48.33%)in comparison with control group which was18-24.9 (100 %). The smoking percentage was (16,67%) in hemodialysis patients compared to control group (10%). The presence of another disease in the hemodialysis patients were hypertension (70 %) followed by diabetes mellitus (25 %), arthritis (23.33%), and cardiovascular disease (20 %). With respect to family history of CKD, (25%) of hemodialysis patients have a family history while the family history of the control group was (6.67%). In the hemodialysis patients, the genotype I/I, I/D, and D/D distribution percentage were 18.33 %, 65 %, and 16.67% respectively compared with the control group which was 33.33 %, 36.67%, and 30 % respectively.
Conclusion: There was a high association between heterozygous genotype (I/D) with the occurrence of CKD. Serum urea level increased in hemodialysis patients had ID genotypes in comparison with II and DD genotypes. Also, of IGF-1 and SADMA has importance as a risk factor or prognosis indicator in adult CKD hemodialysis patients.
In Vitro Anti Acne Activity of Methanolic Extract of Dried Fruit of Embelia ribes
Authors: Prasad Shyam Baboo , Bist Meenu
Published: November 2019

In current investigation, an attempt has been taken to explore the in vitro antiacne activity of methanolic extract of dried
fruit of Embelia ribes. The minimum inhibitory concentration value of the Embelia ribes fruits extract against test
S.epidermidis, Propionibacterium acne and Malassezia furfur was found to be 500 µg/ml ,600µg/ml and 400µg/ml
respectively. It clearly indicated that methanolic extract of dried fruit of Embelia ribes is promising anti-acne agent
against the test microorganisms.