bluuebunny/crossref_metadata_2025 huggingface dataset:
Correlation of Platelet-Derived Growth Factor-BB Levels as a Biomarker of Liver Fibrosis with the Degree of Fibrosis Based on Fibroscan in Chronic Hepatitis B Patients
Authors: Lumban Tobing Richard Togi , Suyata  , Mgs. Irsan Saleh
Published: December 2023

Background: Liver fibrosis is scar tissue that forms due to excessive accumulation of ECM proteins due to chronic liver injury, mediated by cytokines involving complex cellular interactions, such as platelet-derived growth factor-BB (PDGF-BB). In Indonesia, no research has been conducted to determine the correlation between PDGF-BB levels and the degree of liver fibrosis based on fibroscan. The aim of this study is to assess the correlation between PGDF-BB levels and the degree of liver fibrosis based on fibroscan in chronic hepatitis B.

Methods: A cross-sectional study was conducted on the chronic hepatitis B population at the internal medicine clinic of Dr. Mohammad Hoesin General Hospital Palembang from January to Agustus 2023. The assessment uses fibroscan to determine the degree of liver fibrosis, measured in kilopascals (kPa). PDGF-BB levels measured by ELISA.

Results: From 40 subjects, the majority of chronic hepatitis B patients were women (57,5%). The lowest PDGF-BB level was found in chronic hepatitis B patients with fibroscan F0, and the highest PDGF-BB level in fibroscan F4. Fibroscan results are directly proportional to PDGF-BB level.

Conclusion: PDGF-BB has a strong positive correlation with the degree of fibroscan in chronic hepatitis B patients in Dr. Mohammad Hoesin General Hospital. The higher the range of PDGF-BB levels, the higher the degree of fibroscan in chronic hepatitis B patients.
Comparing efficacy and safety of upfront treatment strategies for anaplastic lymphoma kinase-positive non-small cell lung cancer: a network meta-analysis
Authors: Filetti Marco , Lombardi Pasquale , Falcone Rosa , Giusti Raffaele , Giannarelli Diana , Carcagnì Antonella , Altamura Valeria , Scambia Giovanni , Daniele Gennaro
Published: December 2023

Aim: This article is based on our previous research, which was presented as a post at the Congress Aiom 2022 Congress and published in Tumori Journal as Conference Abstract (Tumori J. 2022;108:1–194. doi: 10.1177/03008916221114500). In this paper, a comprehensive presentation of all the achieved results is provided. Several tyrosine kinase inhibitors (TKIs) have been investigated to treat patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC). However, direct comparisons between these TKIs are lacking, with many only being compared to crizotinib. To address this gap, a network meta-analysis was conducted to compare the efficacy and safety of various first-line systemic therapies for ALK-positive NSCLC.
Methods: A thorough search of PubMed, Embase, and Cochrane Library was performed to identify randomized controlled trials (RCTs) published between January 01, 2000 and April 01, 2022, and included trials that investigated upfront treatments for this molecular subgroup and reported overall survival (OS), progression-free survival (PFS), objective response rate (ORR), and adverse events (AEs) of grade 3 or higher (grade ≥ 3 AEs).
Results: The analysis included 9 RCTs with 2,443 patients receiving eight different treatments: alectinib (at two different dosages), brigatinib, ceritinib, crizotinib, ensartinib, lorlatinib, and chemotherapy. Second and third-generation TKIs significantly prolonged PFS compared to crizotinib, with lorlatinib having the highest probability of yielding the most favorable PFS, followed by alectinib (300 mg or 600 mg). However, only alectinib has been shown to significantly prolong OS compared to crizotinib to date. Lorlatinib appears superior in reducing the risk of central nervous system (CNS) progression, followed by alectinib 600 mg. Ceritinib had the highest rate of AEs, followed by lorlatinib and brigatinib.
Conclusions: Based on the network meta-analysis, alectinib and lorlatinib emerged as the most promising upfront treatment options. These treatments provide prolonged disease control while maintaining an acceptable safety profile.
Sustainable Use of Natural and Cultural Resources in the Cross-Border Region Slovenia – Croatia
Authors: Waniek Malgorzata , Franco Mara , Correia Ricardo , Gómez José Manuel Naranjo , Vulevic Ana , Castanho Rui Alexandre
Published: December 2023

One example of cross-border cooperation is between the two neighboring Balkan countries of Slovenia and Croatia. Recently, the quality and intensity of this cooperation have been significantly affected by the outbreak of the Coronavirus pandemic. In this context, this article examines the quality of balanced cross-border cooperation between Croatia and Slovenia, the exploitation of hitherto unexploited potential for increasing the utilization of the region’s natural and cultural resources, and the possibility of rebuilding and developing the tourism sector; in fact, it was in decline as a consequence of the pandemic. Besides, improving the quality of the environment and raising the standard of living and quality of life for the people living in the border areas was another objective. Slovenia and Croatia are promoting a sustainable, safe, and vibrant border area by supporting smart approaches to the protection, mobilization, and management of natural and cultural resources. People living, working, or visiting the area have seen many benefits from this. To provide innovative, smart, and practical solutions that help preserve and enhance the quality of the environment and its diverse identity as well as activate its socioeconomic potential, the main focus has been on harnessing the natural and cultural values of the area. It has been achieved by increasing opportunities for institutional cooperation at all levels to ensure a safe and vibrant environment.
Effect of Innovation Resources on Sustainable Competitive Advantage: The Moderating Role of Responsible Innovation from Evidence of Hospitality Industry in Vietnam
Authors: Ngan Nguyen Thi Huyen , Hanh Duong Hong , Lan Hoang Thi
Published: December 2023

This paper presents a study on the role of innovation resources, innovation capabilities, and especially the mediating role of responsible innovation in increasing sustainable competitive advantage (SCA) of enterprises in the competitive environment. This study is quantitative research that is applied in 1-5-star hotels in Hanoi, Vietnam. Research results indicate that innovation resources have positive effects on product and process innovation capabilities, responsible innovation, and SCA; Product and process innovation capabilities have positive effects on responsible innovation; Responsible innovation has a positive effect on SCA and plays the mediating role that strengthens the positive effect of innovation resources and innovation capabilities on SCA. These results make a theoretical contribution in providing empirical evidence demonstrating the important role of innovation resources, innovation capabilities, and especially responsible innovation. Therefore, useful information is delivered to managers to create innovation resources, strengthen innovation capabilities, and responsible innovation to increase enterprises’ SCA.
Pien Tze Huang alleviates Concanavalin A-induced autoimmune hepatitis by regulating intestinal microbiota and memory regulatory T cells
Authors: Zeng Xin , Liu Miao-Hua , Xiong Yi , Zheng Lin-Xin , Guo Kai-En , Zhao Hai-Mei , Yin Yu-Ting , Liu Duan-Yong , Zhou Bu-Gao
Published: December 2023

BACKGROUND

Traditional Chinese medicine has used the drug Pien Tze Huang (PTH), a classic prescription, to treat autoimmune hepatitis (AIH). However, the precise mode of action is still unknown.

AIM

To investigate the mechanism of PTH in an AIH mouse model by determining the changes in gut microbiota structure and memory regulatory T (mTreg) cells functional levels.

METHODS

Following induction of the AIH mouse model induced by Concanavalin A (Con A), prophylactic administration of PTH was given for 10 d. The levels of mTreg cells were measured by flow cytometry, and intestinal microbiota was analyzed by 16S rRNA analysis, while western blotting was used to identify activation of the toll-like receptor (TLR)2, TLR4/nuclear factor-κB (NF-κB), and CXCL16/CXCR6 signaling pathways.

RESULTS

In the liver of mice with AIH, PTH relieved the pathological damage and reduced the numbers of T helper type 17 cells and interferon-γ, tumor necrosis factor-alpha, interleukin (IL)-1β, IL-2, IL-6, and IL-21 expression. Simultaneously, PTH stimulated the abundance of helpful bacteria, promoted activation of the TLR2 signal, which may enhance Treg/mTreg cells quantity to produce IL-10, and suppressed activation of the TLR4/NF-κB and CXCL16/CXCR6 signaling pathways.

CONCLUSION

PTH regulates intestinal microbiota balance and restores mTreg cells to alleviate experimental AIH, which is closely related to the TLR/CXCL16/CXCR6/NF-κB signaling pathway.
Intestinal barrier in inflammatory bowel disease: A bibliometric analysis
Authors: Luan Wen-Yu , Yang Zhe , Chen Xiao-Dong , Zhang Tong-Tong , Zhang Fang , Miao Yan-Dong
Published: December 2023

The primary objective of this investigation was to examine the evolving trajectories and pivotal focal points within the domain of research on intestinal barriers with regard to inflammatory bowel disease (IBD). Publications germane to the intestinal barrier in the context of IBD were procured from the Science Citation Index Expanded within the Web of Science Core Collection database. Bibliometric scrutiny and visualization were executed employing the R package "bibliometrix" through the R software platform (version: 4.3.0). A comprehensive compilation of 7344 English-language articles spanning from January 1, 2001 to December 31, 2021 was meticulously identified and included in the analysis. Remarkably, China emerged as the preeminent force in the realm of intestinal barrier research in relation to IBD. The significance of the intestinal barrier in the context of IBD has been progressively and comprehensively acknowledged. This recognition has ushered in a fresh therapeutic perspective that offers the promise of enhancing the management of inflammation and prognostication.
OBJECTIVES, PROBLEMS, AND COUNTERMEASURES OF IMPLEMENTING GENERAL EDUCATION IN LOCAL ENGINEERING COLLEGES
Authors: Cai Yunlong , Wang Jingfeng , Zhou Lili
Published: December 2023

In recent years, there have been more and more explorations and research on general education in local engineering colleges in China, which are highly valued and favored, but limited by the shackles of traditional professional educational mechanisms and ideological concepts, the reform of general education in local engineering colleges is in a dilemma, which is mainly manifested in the following aspects: lack of understanding of general education concept, lack of teachers and lack of management of general education. Therefore, local engineering colleges must get rid of the current situation. Firstly, they should establish clear general education objectives; secondly, they should strengthen the construction of general education teachers; and thirdly, they should improve the quality of general education management, to enhance the effectiveness of general education.
De las enfermedades de los ojos y de su tratamiento en la Antigüedad
Authors: Gutierrez Alfonso , Giménez Pardo Consuelo
Published: December 2023

Los ojos en la Antigüedad han sido objeto de culto para muchas civilizaciones. En esta reseña se realiza un repaso sobre el poder de los ojos, las enfermedades que los afectaban y los diferentes tratamientos utilizados a lo largo del tiempo. Este tema, los ojos, es un vehículo que nos permite avanzar por la medicina de la antigüedad y su configuración hasta sentar las bases de lo que conocemos hoy día.
La enfermedad renal crónica, una epidemia silenciosa
Authors: De Sequera Patricia
Published: December 2023

La Enfermedad Renal Crónica (ERC) representa uno de los principales problemas de salud pública debido a su elevada prevalencia, a la gravedad de sus complicaciones y elevada morbimortalidad cardiovascular asociada, y por último al impacto en los sistemas de salud, con elevados costes económicos y también sociales. En España, según los estudios epidemiológicos afecta aproximadamente al 10% - 15% de la población adulta. Es comúnmente llamada la enfermedad “silenciosa”, porque a pesar de esta elevada prevalencia (se estima que 1 de cada 7 españoles adultos padecen esta enfermedad) existe un infradiagnóstico, debido a que la ERC no produce síntomas hasta que no está en estadios muy avanzados. Entre las causas que pueden llevar a la ERC en primer lugar está la diabetes, enfermedad cuya incidencia sigue aumentando, fundamentalmente relacionada con la obesidad y que representa la causa del 25% de los pacientes que inician el tratamiento renal sustitutivo. La segunda causa es la no filiada o desconocida que constituye un 18%. El diagnóstico es sencillo, con una analítica de sangre que incluya la determinación de la creatinina, que nos permite medir el filtrado glomerular (funcionamiento de los riñones), y también la determinación en orina de la albúmina. La ERC se clasifica en 5 estadios o grados, en el 1 la función renal es normal, pero hay alteraciones en la composición de la orina o estructura del riñón y en el 5 el paciente tiene un filtrado o función renal inferior a 15 ml/min y está a las puertas de la diálisis o el trasplante. La complicación más importante de la ERC es que aumenta el riesgo cardiovascular. Como en toda enfermedad crónica, la base de su prevención es poder detectarla precozmente. En los estadios finales cuando los riñones no funcionan hay que recurrir a la diálisis o el trasplante, siendo esta última la mejor opción. España es uno de los países líderes en trasplante gracias a un programa de donaciones avanzado y riguroso.
Hubungan Hasil Belajar Kognitif Dengan Kreativitas Menggunakan Model Project Based Learning (PjBL) Berbantuan Media Assemblr Edu Berdasarkan Gender
Authors: Siti Patmawati  , Sistiana Windyariani  , Aa Juhanda
Published: December 2023

Penelitian ini dilatar belakangi oleh rendahnya hasil belajar kognitif dan kreativitas, berdasarkan observasi dan wawancara rendahnya hasil belajar kognitif dilihat pada nilai peserta didik kurang dari KKM 70. Sedangkan kreativitas dilihat ketika proses praktikum. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara hasil belajar kognitif dengan kreativitas peserta didik di SMP IT Al-Madani Cilaku dengan menggunakan model Project Based Learning (PjBL) dengan bantuan media Assemblr Edu. Jenis penelitian yang digunakan adalah pre-experimental dengan desain tipe one group pre-test post-test design Subjek penelitian diambil peserta didik kelas VIII SMP IT Al-Madani Cilaku. Instrumen hasil belajar kognitif mengacu pada sistem Taksonomi Bloom Revisi berupa soal pilihan ganda dengan taraf kognitif C1-C6. Selanjutnya, tes kreativitas dilakukan dengan angket pernyataan dan skala pengukuran likert pada empat dimensi, yaitu fluency, flexibility, elaboration dan originality. Hasil menunjukkan adanya hubungan antara hasil belajar kognitif dan kreativitas menggunakan model Project Based Learning (PjBL) berbantuan media Assemblr Edu berbasis gender, dengan nilai korelasi pearson 0.878 untuk laki-laki dan 0.808 untuk perempuan. Hasil penelitian menunjukkan adanya hubungan yang positif antara hasil belajar kognitif dan kreativitas dengan kategori korelasi kuat.
Peningkatan Hasil Belajar IPA melalui Strategi Pembelajaran Crossword Puzzle Berbasis Aplikasi Crossword Labs di SD Kelas V
Authors: Rosita Putri Rahmi Haerani  , Vina Aulia Putri  , Muhlis Muhlis , Muh. Ramli Buhari  , Andi Asrafiani Arafah
Published: December 2023

Penelitian ini dilatarbelakangi oleh nilai hasil belajar IPA yang rendah di kelas V SDN 001 Loa Janan Ilir. Penelitian ini bertujuan untuk mengetahui peningkatan hasil belajar IPA melalui strategi pembelajaran crossword puzzle berbasis aplikasi crossword labs pada peserta didik kelas V SDN 001 Loa Janan Ilir tahun 2022/2023. Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK) dengan subjek penelitian adalah peserta didik kelas V SDN 001 Loa Janan Ilir dengan jumlah 28 dan objek penelitian ini adalah hasil belajar IPA. Observasi, tes, dan dokumentasi merupakan teknik pengumpulan data yang digunakan dalam penelitian ini. Teknik analisis data menggunakan persentase aktivitas guru dan peserta didik, ketuntasan hasil belajar, rata-rata, nilai akhir, dan peningkatan hasil belajar peserta didik. Hasil penelitian menunjukkan nilai rata-rata pada pra siklus yaitu 56,78 dengan persentase tuntas 32,14%, pada siklus I menjadi 70 dengan persentase peningkatan hasil belajar sebesar 23,28% dan persentase tuntas sebesar 57,14%. Pada siklus II nilai rata-rata mengalami peningkatan menjadi 80,18 dengan persentase peningkatan 41,21% dan persentase tuntas sebesar 85,71%. Berdasarkan hasil penelitian yang telah dilakukan oleh peneliti, disimpulkan bahwa terdapat adanya peningkatan hasil belajar IPA melalui strategi pembelajaran crossword puzzle berbasis aplikasi crossword labs pada peserta didik kelas V SDN 001 Loa Janan Ilir tahun pembelajaran 2022/2023.
Peningkatan Keterampilan Proses Sains Siswa Sekolah Dasar melalui Model Pembelajaran Berbasis Masalah
Authors: Jery Dariansyah  , Sumianto Sumianto , Melvi Lesmana Alim  , Moh Fauziddin  , Vitri Angraini Hardi
Published: December 2023

Penelitian ini dilatar belakangi oleh rendahnya keterampilan proses sains siswa kelas V SD Muhammadiyah 028 Penyasawan. Penelitian ini bertujuan untuk menerapkan model pembelajaran berbasis masalah dalam meningkatkan keterampilan proses sains siswa kelas V SD Muhammadiyah Penyasawan yang berjumlah 22 peserta didik. Penelitian yang digunakan adalah Penelitian Tindakan Kelas (PTK) yang dilaksanakan dalam dua siklus pembelajaran. Setiap siklus terdiri dari dua pertemuan dan empat tahap pembelajaran yaitu: perencanaan, pelaksanaan, observasi, dan refleksi. Teknik pengumpulan data berupa dokumentasi, observasi, dan tes. Sedangkan teknik analisis data menggunakan analisis kualitatif dan analisis kuantitatif. Berdasarkan analisis data diperoleh hasil keterampilan proses sains siswa kelas V SD Muhammadiyah 028 Penyasawan pada pratindakan 36%. Pada siklus I pertemuan I dengan persentase ketuntasan belajar 55% dan pada siklus I pertemuan II mengalami peningkatan dengan persentase 68%. Pada siklus II pertemuan I mengalami peningkatan juga dengan ketuntasan belajar 77%, dan pada siklus II pertemuan II mengalami peningkatan lagi dengan persentase ketuntasan belajar 86%. Dengan demikian dapat disimpulkan bahwa dengan menggunakan model pembelajaran berbasis masalah dapat meningkatkan keterampilan proses sains kelas V SD Muhammadiyah 028 Penyasawan.
Implementasi Project Based Learning untuk Meningkatkan Keterampilan Berpikir Kreatif Mahasiswa dengan Lesson Study
Authors: Nuraini Nuraini
Published: December 2023

Penelitian ini bertujuan untuk meningkatkan kemampuan berpikir kreatif mahasiswa dengan menerapkan project based learning melalui lesson study. Penelitian ini menggunakan penelitian tindakan kelas melalui lesson study dengan 3 open class dengan tahapan plan, do dan see dengan subjek berjumlah 32 mahasiswa program studi pendidikan biologi Universitas Hamzanwadi. Instrumen dalam penelitian ini meliputi lembar observasi yang digunakan untuk mengukur aktivitas mahasiswa selama pembelajaran dan tes kemampuan berpikir kreatif yang digunakan untuk mengukur kemampuan berpikir kreatif mahasiswa setelah pembelajaran. Data yang terkumpul dianalisis menggunakan statistik deskriptif. Hasil analisis menunjukkan bahwa skor aktivitas mahasiswa selama proses pembelajaran dari open class pertama, kedua dan ketiga sebesar 73,62%, 80,09% dan 84,72% terjadi peningkatan aktivitas rata-rata sebesar 5,56%. Data skor kemampuan berpikir kreatif mahasiswa selama open class diperoleh masing-masing sebesar 75%, 81,25% dan 93,75% atau meningkat rata-rata sebesar 9,38%. Kesimpulan dari penelitian ini adalah penerapan pembelajaran berbasis proyek melalui lesson study dapat meningkatkan kemampuan berpikir kreatif mahasiswa. Implementasi PjBL melalui lesson study dalam pembelajaran diyakini dapat meningkatkan profesionalisme dosen dan mengajarkan pentingnya bagaimana bekerja sama dengan dosen mitra untuk mencapai tujuan pembelajaran tertentu sehingga penerapan pembelajaran PjBL melalui lesson study perlu dilakukan disemua jenjang pendidikan mulai dari Sekolah Dasar hingga Perguruan Tinggi.
Analisis Kreativitas Mahasiswa dengan Menggunakan Model Project Based Learning
Authors: Jeliana Veronika Sirait  , Erlida Amnie  , Hebat Shidow Falah
Published: December 2023

Kreativitas merupakan kemampuan dalam menyampaikan suatu ide atau gagasan baru yang tergantung pada pemikiran keratif. Mahasiswa yang berperan sebagai generasi penerus dituntut untuk memiliki pemikiran yang kreatif dalam menemukan sesuatu yang dapar digunakan untuk mengatasai permasalahan sehari-hari. Namun pada kenyataannya masih banyak mahasiswa yang belum mampu menyampaikan ide kreatifnya. Penelitian ini merupakan penelitian deskriptif kuantitatif yang bertujuan untuk menganalisis kreativitas mahasiswa pada materi Fluida setelah penerapan model pembelajaran PjBL. Teknik pengumpulan data yang digunakan adalah observasi. Subjek penelitian ini adalah mahasiswa semester I Teknik Kimia Universitas Jambi. Data diperoleh melalui Creativity Product Analysis Matrix (CPAM). Dimensi kreativitas yang digunakan adalah kebaruan, resolusi, dan elaborasi. Data dalam penelitian ini dianalisis secara deskriptif. Berdasarkan hasil perolehan observasi yang ditemukan pada setiap tahap kegiatan, kreativitas mahasiswa dalam kategori baik sebanyak lebih dari 77%. Berdasarkan hasil penelitian, disimpulkan bahwa penerapan model pembelajaran Project Based Learning pada mata kuliah Fisika Dasar 1 mampu meningkatkan kreativitas mahasiswa.
Pengembangan e-Modul Berbasis Inquiry Science Issues Tema Tanahku Tercemar untuk Melatih Kemampuan Berpikir Kritis Siswa SMP Kelas VII
Authors: Rosminah Rosminah , Suroso Mukti Leksono  , R. Ahmad Zaky El Islami
Published: December 2023

Kegiatan pembelajaran yang berorientasi pada kemampuan berpikir kritis siswa masih belum terlaksana secara optimal. Kemampuan berpikir kritis dapat di bangun dengan mengembangkan produk e-modul berbasis inquiry science issues. Tujuan penelitian ini yaitu mendeskripsikan efisiensi e-modul berbasis inquiry science issues tema tanahku tercemar untuk melatih kemampuan berpikir kritis siswa SMP kelas VII. Manfaat penelitian ini yaitu bahan ajar e-modul ini dapat membantu guru dan siswa dalam kegiatan proses belajar serta menambah keterbatasan bahan ajar yang ada disekolah. Penelitian pengembangan ini dengan model Sugiono yang dibatasi sampai uji coba terbatas. Instrumen penelitian ini menggunakan angket validasi ahli dan respon siswa. Hasil validasi e-modul oleh ahli materi didapatkan persentase sebesar 86,9% (sangat valid), ahli media didapatkan persentase sebesar 91,08% (sangat valid) dan ahli praktisi didapatkan persentase sebesar 85,5% (sangat valid). Hasil tingkat efisiensi e-modul didapatkan persentase sebesar 86,9% (sangat efisien). Dengan demikian, e-modul berbasis inquiry science issues tema tanahku dapat digunakan dalam proses pembelajaran IPA di sekolah.
Pengaruh Penggunaan Media Animasi Berbasis Plotagon untuk Meningkatkan Hasil Belajar Siswa
Authors: Eva Margaretha Saragih  , Syahriani Sirait
Published: December 2023

Penelitian ini bertujuan untuk meningkatkan hasil belajar peserta didik setelah digunakannya media animasi berbasis plotagon yang diadakan di SD N 010246 Banjar. Manfaat media animasi yang menarik seperti Plotagon dapat membantu meningkatkan motivasi belajar siswa. Keterlibatan siswa dalam pembelajaran dapat ditingkatkan melalui penggunaan teknologi yang menarik dan relevan dengan minat mereka. Penelitian ini menggunakan rancangan penelitian one-group pretest-posttest design. Penelitian ini menggunakan teknik sampling jenuh yakni sampel penelitian yang akan digunakan adalah semua anggota populasi. Subjek yang digunakan dalam penelitian ini adalah peserta didik kelas V SD N 010246 Banjar yang berjumlah 26 peserta didik. Hasil penelitian menunjukkan bahwa penggunaan media plotagon berpengaruh secara signifikan dan dapat meningkatkan hasil belajar peserta didik. Hasil tersebut di dapat dari hasil pengujian uji hipotesis diperoleh perhitungan t_hitung= 3,559 dan t_tabel = 1,675. Dengan dk = 51. Maka t_hitung > t_tabel dengan 3,559 > 1,675, sehingga H0 ditolak dan Ha diterima, yang artinya terdapat pengaruh penggunaan media animasi berbasis plotagon untuk meningkatkan hasil belajar siswa.
ROA sebagai determinan pembiayaan pada Bank Muamalat Indonesia
Authors: Astuti Wuku , Artha Bhenu
Published: December 2023

Lembaga keuangan perbankan merupakan lembaga keuangan yang bertugas menghimpun dana dari masyarakat dan menyalurkan kembali ke masyarakat guna memenuhi kebutuhan dana bagi pihak yang membutuhkan, baik untuk kegiatan produktif maupun konsumtif. Bank syariah merupakan lembaga keuangan bank yang berprinsip syariah yang dalam pelaksanaan operasionalnya menggunakan prinsip-prinsip syariah Islam. Operasional bank syariah telah beberapa kali diteliti, dan penelitian ini berfokus pada kinerja keuangan bank syariah. Prinsip syariah adalah aturan perjanjian berdasarkan hukum Islam antara bank dengan pihak lain untuk menyimpan dana dan atau pembiayaan kegiatan usaha, atau kegiatan lainnya yang dinyatakan sesuai dengan syariah. Penelitian ini bertujuan untuk mengetahui pengaruh return onn assets (ROA) terhadap pembiayaan murabahah, mudharabah, dan musyarakah di Bank Muamalat Indonesia. Metode kuantitatif digunakan dalam penelitian ini. Data yang digunakan diambil dari laporan triwulanan periode Juni 2015 – Maret 2023. Hasil analisis menunjukkan bahwa ROA berpengaruh positif signifikan terhadap pembiayaan murabahah, mudharabah, dan musyarakah. Saran untuk penelitian selanjutnya juga disampaikan disini.
Unveiling the Impacts of the Russia Ukraine War on International Trade: A Systematic Literature Review
Authors: Paryan Paryan , Hashfi Muhammad
Published: December 2023

ABSTRACT

This literature review examines the impact of the Russia-Ukraine war on international trade and global economic stability, identifying key findings and research gaps. Using a systematic approach, the review analyzes relevant studies published between 2022 and 2023, employing bibliometric analysis techniques and the Scopus database. The war disrupts food and energy supply chains, posing challenges to food security and availability, while significantly affecting European consumption patterns and energy resources. Existing studies lack a comprehensive analysis of the war's impact on international trade. The findings provide insights into the complex relationship between the war and trade, offering guidance for policymakers. Further research is recommended for conducting in-depth analysis of the war's impact on specific trade sectors, enabling a better understanding of changes in trade patterns and their implications for the global economy.

ABSTRAK

Tinjauan literatur ini mengkaji dampak perang Rusia-Ukraina terhadap perdagangan internasional dan stabilitas ekonomi global, serta mengidentifikasi temuan-temuan utama dan kesenjangan penelitian. Dengan menggunakan pendekatan sistematis, tinjauan ini menganalisis studi relevan yang diterbitkan antara tahun 2022 dan 2023, menggunakan teknik analisis bibliometrik dan database Scopus. Perang ini mengganggu rantai pasokan pangan dan energi, menimbulkan tantangan terhadap ketahanan dan ketersediaan pangan, serta secara signifikan mempengaruhi pola konsumsi dan sumber daya energi Eropa. Penelitian yang ada saat ini kurang memberikan analisis komprehensif mengenai dampak perang terhadap perdagangan internasional. Temuan ini memberikan wawasan tentang hubungan kompleks antara perang dan perdagangan, serta memberikan panduan bagi para pembuat kebijakan. Penelitian lebih lanjut disarankan untuk melakukan analisis mendalam mengenai dampak perang terhadap sektor perdagangan tertentu, sehingga memungkinkan pemahaman yang lebih baik mengenai perubahan pola perdagangan dan implikasinya terhadap perekonomian global.

 

Kata kunci: Perdagangan Internasional, Perang Rusia-Ukraina, Gangguan Perdagangan, Stabilitas Ekonomi, Gangguan Rantai Pasokan
The Role of Human Resource Competence and Entrepreneurial Motivation on the Performance of Women Entrepreneurs
Authors: Juniarta I , Merta I , Ardiansyah Wisnu
Published: December 2023

This research aims to investigate the impact of human resource competence and entrepreneurial motivation on the performance of women entrepreneurs in the fashion industry of Klungkung Regency, Bali, Indonesia, specifically within micro, small and medium enterprises (MSMEs). The study draws upon management theory, middle-range human resource theory, and applied theories related to human resource competence, motivation, and entrepreneurship. The research methodology employed is quantitative, using questionnaires as the primary data collection tool. The study involves a sample of 54 SME businesses, and data analysis is conducted using SPSS software version 24. Three hypotheses were tested in this research. The results indicate that the variable of human resource competence has a significant positive influence on entrepreneurial performance. Furthermore, human resource competence also has a significant positive effect on entrepreneurial motivation. The variable of entrepreneurial motivation also significantly influences entrepreneurial performance. However, it is noteworthy that the impact of human resource competence and entrepreneurial motivation on entrepreneurial performance is considered relatively modest.

Keywords: Entrepreneur Performance, HR Competence, Entrepreneurial Motivation, Women Entrepreneurs, Fashion Industry.

 

ABSTRAK

Penelitian ini bertujuan untuk menyelidiki dampak kompetensi sumber daya manusia dan motivasi berwirausaha terhadap kinerja para pengusaha wanita di industri fashion Kabupaten Klungkung, Bali, Indonesia, khususnya dalam usaha mikro, kecil, dan menengah (UMKM). Studi ini mengacu pada teori manajemen, teori sumber daya manusia tingkat menengah, dan teori terapan terkait kompetensi sumber daya manusia, motivasi, dan kewirausahaan. Metodologi penelitian yang digunakan bersifat kuantitatif, dengan menggunakan kuesioner sebagai alat pengumpulan data utama. Studi ini melibatkan sampel dari 54 usaha UMKM, dan analisis data dilakukan menggunakan perangkat lunak SPSS versi 24. Tiga hipotesis diuji dalam penelitian ini. Hasil penelitian menunjukkan bahwa variabel kompetensi sumber daya manusia memiliki pengaruh positif yang signifikan terhadap kinerja berwirausaha. Selain itu, kompetensi sumber daya manusia juga memiliki pengaruh positif yang signifikan terhadap motivasi berwirausaha. Variabel motivasi berwirausaha juga berpengaruh signifikan terhadap kinerja berwirausaha. Namun, perlu dicatat bahwa dampak kompetensi sumber daya manusia dan motivasi berwirausaha terhadap kinerja berwirausaha dianggap relatif sederhana

Kata kunci: Kinerja Berwirausaha, Kompetensi SDM, Motivasi Berwirausaha, Pengusaha Wanita, Industri Fashion
Consumer Value and Risk Perception on Consumer Purchase Intention in Athletic Shoe Markets
Authors: Bursan Rinaldi
Published: December 2023

In the ever-evolving sports equipment industry, iconic brands like Adidas, Nike, and Puma have transcended their athletic origins to become fashion symbols, adapting to the preferences of the modern consumer. Brand recognition plays a crucial role in distinguishing quality products, aiding effective marketing efforts, segmentation, and customer loyalty. This study delves into the brand management strategies of these leading athletic shoe companies, focusing on how they maintain their brand presence in a fiercely competitive market and adapt to changing consumer trends. Employing a quantitative approach, we examined the relationship between Consumer Value, Brand Awareness, and Risk Perception and their impact on Purchase Intention among consumers seeking to purchase Nike shoes. Our findings highlight the significant influence of these factors on Purchase Intention, reinforcing their importance in consumer decision-making. We recommend strategies for Nike, such as enhancing product quality and introducing distinctive shoe designs, leveraging social media for brand awareness, and implementing features to reduce counterfeit risks, all aimed at shaping the future of the athletic shoe industry.

Keywords: Athletic footwear, brand management, consumer behavior, purchase intention, sportswear industry

 

ABSTRAK

Dalam industri peralatan olahraga yang terus berubah, merek-merek terkenal seperti Adidas, Nike, dan Puma telah melampaui akar mereka dalam olahraga untuk menjadi simbol mode, mengikuti preferensi konsumen modern. Pengenalan merek memainkan peran penting dalam membedakan produk berkualitas, membantu upaya pemasaran yang efektif, segmentasi, dan membangun loyalitas pelanggan. Penelitian ini menyelidiki strategi manajemen merek dari perusahaan sepatu olahraga terkemuka ini, dengan fokus pada bagaimana mereka menjaga kehadiran merek mereka di pasar yang sangat kompetitif dan beradaptasi dengan tren konsumen yang berubah. Dengan menggunakan pendekatan kuantitatif, kami mengeksplorasi hubungan antara Nilai Konsumen, Kesadaran Merek, dan Persepsi Risiko serta dampaknya pada Niat Pembelian di kalangan konsumen yang ingin membeli sepatu Nike. Hasil penelitian kami menunjukkan pengaruh signifikan dari faktor-faktor ini pada Niat Pembelian, yang mengukuhkan pentingnya mereka dalam keputusan konsumen. Kami juga memberikan rekomendasi strategis untuk Nike, seperti meningkatkan kualitas produk dan menghadirkan desain sepatu yang unik, memanfaatkan media sosial untuk meningkatkan kesadaran merek, dan mengimplementasikan fitur-fitur untuk mengurangi risiko barang palsu, semuanya bertujuan untuk membentuk masa depan industri sepatu olahraga..

Kata kunci: Sepatu olahraga, manajemen merek, perilaku konsumen, niat beli konsumen, industri pakaian olahraga.
The Effect of Compensation and Motivation on Performance Employees at Public Works and Spatial Planning Service of North Aceh
Authors: Desky Harjoni
Published: December 2023

This research explores the intricate relationship between compensation, motivation, and employee performance within the Public Works and Spatial Planning Office of North Aceh Regency. Through a quantitative approach employing multiple and simple linear regression analyses with SPSS, the study investigates the impact of compensation and motivation on employee performance, using a sample of 60 employees selected through random sampling. The findings indicate that both compensation and motivation significantly contribute to heightened employee performance, constituting crucial elements for organizational success. The compensation regression coefficient is 0.569, affirming that increased compensation positively influences employee performance. Similarly, the motivational regression coefficient is 1.022, suggesting that heightened motivation positively impacts employee performance. The study underscores the theoretical significance of recognizing compensation and motivation as pivotal factors in human resource management. Practical implications include the need for well-structured compensation systems and effective motivational strategies to optimize employee performance. Despite these contributions, caution is advised in generalizing findings, and future research could delve into additional factors influencing employee performance for a more comprehensive understanding in the public sector.
The Influence of Leadership Style and Teamwork on Work Stress at Bekasi City Police
Authors: Irfana Tungga , Chairunisa Ririn , Diana Tungga
Published: December 2023

Job stress is a critical aspect that needs to be considered, considering the level of pressure and challenges in the dynamic police environment. High levels of stress can result in decreased welfare, mental health and productivity of members, which in turn can affect the quality of police services. Leadership style and teamwork are considered factors that can influence work stress levels. Good leadership can provide clear direction, support and empower members, while strong teamwork creates a positive and collaborative work environment. Therefore, a deep understanding of how leadership styles and teamwork contribute to job stress levels is essential for designing effective management strategies. The purpose of this research is to find out how leadership style and teamwork influence the work stress of members at the Bekasi City Police. The sampling technique used in this research was saturated sampling. The sample used in this research were members of the HR department of the Bekasi City Police with a sample size of 35 members as respondents. The variables used in this research are Leadership Style (X1), Teamwork (X2) and Work Stress (Y). This research is a type of quantitative research whose data processing uses SPSS version 17. Using multiple linear regression analysis methods, normality tests, descriptive tests, hypothesis tests and f tests (simultaneous). The results of this research show that the Leadership Style variable (X1) has a significant effect on the Work Stress variable (Y), the Teamwork variable (X2) has a positive effect on Work Stress (Y). So, it can be concluded that there is a positive influence between Leadership Style (X1) and Teamwork (X2) together on Job Stress (Y).
Digital Marketing, Brand Image and Customer Loyalty at Kopi Kenangan in Pekanbaru
Authors: Tarigan Elma , Fauzi Faradiba , Ricy Muhammad , Wandhira Eka , Nofirda Fitri
Published: December 2023

Coffee has become one of the most renowned beverages globally, particularly gaining prominence in Indonesia as a significant commodity. In recent times, the appeal of coffee has expanded among young people, particularly women, broadening its consumer base beyond its traditional audience of men and adults. With the growing popularity of coffee, coffee shop initiatives have surged, each employing various strategies to attract customers. This study aims to explore the impact of digital marketing on enhancing the brand image and customer loyalty of coffee shops, Kopi Kenangan in Pekanbaru. The qualitative research method employed a descriptive approach with case study research, incorporating surveys and interviews with employees of Kopi Kenangan in Pekanbaru. The results indicate a positive and substantial influence of digital marketing on the brand image of coffee shops, with a similarly positive and significant impact on customer loyalty.
Store Atmosphere, Price Discount and Purchasing Decisions of Shoe Stores in Bandar Lampung
Authors: Julia Angelica , Roslina Roslina , Nabila Nuzul
Published: December 2023

This study investigates the influence of discounts and store atmosphere on purchasing decisions in shoe stores in Bandar Lampung, recognizing the evolving role of shoes from a basic foot protection necessity to a symbol of fashion. The purpose is to discern the impact of these factors on consumer behavior, particularly in a dynamic retail setting. The research, involving 100 respondents, employs purposive sampling to ensure representation of the population. Criteria for respondent selection include being over 17 years old and having made purchases in shoe stores. Data collection involves validated and reliable questionnaires, and SPSS version 26 is employed for statistical analysis, utilizing the multiple linear regression method. The results reveal that discounted prices and store atmosphere significantly influence purchasing decisions. These findings underscore the contemporary importance of factors beyond utilitarian aspects, shedding light on the interplay between economic considerations, retail strategies, and consumer preferences. Implications of this study extend to both marketers and consumers, guiding strategies for retailers to enhance the shopping experience and assisting consumers in making informed purchasing decisions in the evolving landscape of the fashion-centric shoe industry.
The Influence of Audit Fee, Audit Tenure, and Auditor Competency on Audit Quality: A Systematic Review
Authors: Fadila Ega , Ramadhyani Yesica , Saputri Yunita , Manurung Herlina
Published: December 2023

Financial audit reports play a crucial role in corporate decision-making, and their quality is impacted by various factors such as audit fees, audit tenure, and auditor competency. Audit fees refer to the costs associated with audit services, audit tenure signifies the duration of the audit firm's responsibility, and auditor competency encompasses the auditor's knowledge, skills, and attitudes. This study employs a systematic review approach, analyzing articles downloaded from the Google Scholar online database covering journals published from 2019 to 2023 using keywords like audit fee, audit tenure, auditor competency, and quality of financial audit reports. The research incorporates 10 quantitative journals, with 5 employing linear regression analysis, 4 using logistic regression analysis, and 1 utilizing the partial least squares method. The findings reveal that a majority of the journals demonstrate a positive and significant correlation between audit fees, audit tenure, auditor competency, and the quality of audit reports. Nonetheless, a few articles assert the absence of a relationship between audit fees, audit tenure, and audit quality. In summary, public accounting firms should regularly assess and formulate strategies concerning audit fees, audit tenure, and auditor competency to enhance client value by producing high-quality, accurate, and dependable financial audit reports.
Implementasi Rapid Application Development Dalam Membangun Sistem Pendaftaran Nikah Secara Online
Authors: Alhafis Ahmad Naufal , Saputera Surya Ade , Andilala Andilala
Published: December 2023

Kantor Urusan Agama (KUA) Kecamatan Bingin Kuning merupakan salah satu Kantor Urusan Agama yang berada di daerah Kabupaten Lebong  Provinsi Bengkulu. Pada KUA Kecaqmatan Bingin Kuning proses pendaftaran pernikahan masih dilakukan secara manual yaitu calon pengantin datang langsung ke KUA dan staf KUA menulis pendaftaran di buku pendataan pernikahan. Pendaftaran yang dilakukan secara manual tersebut menjadi permasalahan yang menghambat pelayanan pendaftaran nikah,misalnya menumpuknya jumlah data, hilangnya data, kesalahan menginput nama calon pengantin dan sering tercecernya pasfoto. Tujuan dari penelitian ini adalah untuk mempermudah proses pendaftaran nikah dan meningkatkan pelayanan publik di KUA Kecamatan Bingin Kuning. Metode pengembangan sistem menggunakan Rapid Application Development (RAD), perancangan sistem menggunakan Data Flow Diagram (DFD) dan menggunakan bahasa pemrograman PHP. Penelitian ini telah menghasilkan sistem informasi pendaftaran nikah pada KUA Kecamatan Bingin Kuning dengan dengan 4 user yaitu admin, calon pengantin, kepala KUA, dan penghulu. Sistem informasi yang dibuat pada KUA Kecamatan Bingin Kuning berhasil mempermudah calon pengantin melakukan pendaftaran pernikahan yang bisa dilakukan dari rumah tanpa harus datang langsung ke KUA dan bisa menghemat waktu.
Sistem Informasi Pelayanan Gangguan Berbasis Web di PT. Telkom Kabupaten Ogan Komering Ulu
Authors: Zahra.M Aprima , Muris Anggraeni Agustin , Rahman Abdul
Published: December 2023

Telkom Indonesia is a State-Owned Enterprise (BUMN) in the field of IT services, ICT and telecommunications networks in Indonesia. PT. Telkom Indonesia has a service that can be used for individuals or companies, namely Indihome. Indihome is a network package, an Indihome Fiber package that provides internet services, interactive TV and home telephones. It takes a design data system for troubleshooting services that can be accessed by customers and suitable technicians to support the smooth running of the process, processing of complaint information and corrective action. 

By using the proposed system correctly, it may be easier to monitor the distribution of complaint information, so as to speed up the repair process. This can also help speed up the presentation of reports that are accurate, timely and relevant so that they can assist management in making decisions. This is intended so that technicians do not face the main obstacles in recording information and monitoring the length of time working on field problems. In order to overcome this problem, we need a design data system service for electrical problems that can be accessed by the appropriate admin to support the smooth running of the process of processing complaint information and corrective action.
Perancangan Media Presentasi Alternatif Menggunakan Focusky Pada Matakuliah Jaringan Komputer di Program Studi PTIK UIN Bukittinggi
Authors: Putri Alya Zulda , Musril Hari Antoni
Published: December 2023

Abstract— The implemlelntation of computer network lectures in the delivery of learlning materials already uses media such as zoom meetings and pdf files. Basically there is nothing wrong in using the media. However, the authors argue that it would be better if it was comblined with the use of presentation medlia-based technology. Meanwhile students said that the material provided was quite understandable, but there was a feleling of bolredom during learning because the media was monotonous in the form of pdf files only, and the contents of each slide were too dense/many. Based on this, the solution given is to design a media presentation.

Research on the deslign of preselntation media using focusky on computer network courses at the PTIK IAIN Bukittinggi study program uses the Research and Development (R&D) method with the DDD-E development model. Media development using the DDD-E model consists of (1) Decide or set progrlam goals and materials, (2) Design or design, namely creating program structures, (3) Develop or developing is prolducing media elements and making media appearance, (4) Evaluate or evaluate, namely checking the entire design and development process. The product tests used in this study are validity tests, practicality tests, and effectiveness tests.

The results of the product test that the author did obtained a validity test from 4 validlators obtained a value of 0.85 with a very valid category, a practiclality test from 3 practicators obtained a value of 0.94 with a very high category, and the effectiveness test from 31 assessors obtained a value of 0, 88 with very effectlive category.

Keyword: Presentaltion Media, Foclusky, Research and Development (R&D)
Rancangan Aplikasi Panduan Ibadah Umroh Dengan Metode Timeline Tree
Authors: Muntahanah Muntahanah , Febrina Nanda , Apridiansyah Yovi
Published: December 2023

Abstract_In Indonesia, the number of Android system smartphone users is 88.37% in 2017. Developments in the field of information technology are currently progressing and developing rapidly, especially in the development of mobile phones, starting from hardware such as Samsung, Lenovo, Oppo, Xiomy and other devices that embed Android. as an operating system because it has many advantages. Umrah worship is mostly carried out by Muslims in Indonesia nowadays due to the long waiting time in the queue to be able to go on pilgrimage. Guidance is given directly or indirectly. Directly, the department of religion or the Hajj Guidance Group (KBIH) conducts hands-on training on guidance for the Hajj and Umrah pilgrimages. In using a guidebook prepared by travel or smartphones that search for prayers via Google and make it a little difficult for the congregation because of the many references. This was considered impractical because the guidebook that was included with the travel party was easily scattered, got wet with water or could even be torn so that it could no longer be used. Created a system that continues the design made in this study so that it can be used by related parties.