bluuebunny/crossref_metadata_2025 huggingface dataset:
Olivenite and cornwallite from the Podlipa copper deposit near Ľubietová, Slovakia
Authors: Števko Martin , Sejkora Jiří , Dolníček Zdeněk
Published: December 2021

An interesting occurrence of olivenite and cornwallite was recently discovered in cavities of quartz at the Podlipa copper deposit near Ľubietová, Slovakia. Olivenite occurs as olive to pale green sprays or radial aggregates consisting of individual acicular crystals up to 5 mm long. Its refined unit-cell parameters (for the monoclinic space group P21/n) are: a 8.6192(13) Å, b 8.2300(11) Å, c 5.9349(8) Å, α 90.055(12)° and V 420.99(7) Å3. Studied olivenite shows intense chemical zoning caused by strong variation of As and P contents. Most of the zones are corresponding to olivenite (with P content ranging between 0.02 to 0.39 apfu), but darker zones or domains of As-rich libethenite (with As content ranging between 0.18 to 0.24 apfu) were occasionally observed. Cornwallite forms dark green massive fillings between olivenite crystals or microcrystalline botryoidal crusts. The refined unit-cell parameters (for the monoclinic space group P21/c) of botryoidal cornwallite from the Podlipa deposit are: a 4.6112(2) Å, b 5.7698(3) Å, c 17.4167(11) Å, β 92.009(5)° and V 463.10(3) Å3. The two compositional types of cornwallite were distinguished. The first type is represented by relatively homogenous aggregates with only minor contents of P (from 0.04 to 0.22 apfu). The second type occurs as polycrystalline fillings with strong chemical zoning and has much more significant variation of As and P contents, representing solid-solution series between P-rich cornwallite (with 1.41 apfu of As and 0.59 apfu of P) and As-rich pseudomalachite (with 1.37 apfu of P and 0.63 apfu of As).
Zeolitová mineralizace s gmelinitem-K z Jedlky u Benešova nad Ploučnicí (Česká republika)
Authors: Pauliš Petr , Hrůzek Libor , Janeček Oldřich , Dolníček Zdeněk , Betz Volker , Vrtiška Luboš , Malíková Radana , Pour Ondřej , Fediuk Ferry
Published: December 2021

A new locality of zeolite minerals occurs on the NE edge of the Jedlka village, at the SE slope of the Hlídka hill, 2 km to W of Benešov nad Ploučnicí (northern Bohemia, Czech Republic). The mineralization is developed in Cenozoic analcime-nepheline tephrite. Ten zeolite mineral species (gmelinite-K, analcime, harmotome, chabazite-Ca, lévyne-Ca, mezolite, natrolite, offretite, phillipsite-K, thomsonite-Ca) were found in small amygdule cavities of tephrite. The most interesting is gmelinite-K, a rare zeolite worldwide, which forms clear, white or slightly yellowish, hexagonal lenticular crystals up to 7 mm, always intergrown with the chabazite-Ca. The unit-cell parameters of gmelinite-K, refined from the powder X-ray data, are a = 13.795 (19), c = 9.811(6) Å and V = 1616.8(3) Å3; its quantitative chemical analyses correspond to the empirical formula (K2.32Ca1.86Sr0.53Na0.20Ba0.19)Σ5.10(Al8.14Si16.01O48)·22H2O.
Pb-Sb zrudnění z Antimonitové žíly, důl Rudolf, Bohutín (Česká republika)
Authors: Škácha Pavel , Sejkora Jiří
Published: December 2021

The Pb-Sb mineralization with dominant stibnite and plagionite and associated semseyite and zinkenite was found in an archive material collected at the Antimonitová vein, Bohutín, Březové Hory ore district (Czech Republic). Plagionite forms subhedral aggregates up to 1 mm in size. The unit-cell parameters of plagionite for monoclinic space group C2/c refined from the X-ray powder data are: a 13.4890(17), b 11.8670(14), c 19.997(2) Å, β 107.199(8)° and V 3057.9(6) Å3. Its chemical composition (average of 26 analyses, based on 30 apfu) corresponds to the empirical formula Pb5.02Sb8.15S16.82. Associated zinkenite is forming subhedral crystals up to 1 mm in size. Its empirical formula can be expressed as (Cu0.25Ag0.02Fe0.01)Σ0.28Pb9.22Sb22.19S41.31 (average of 26 analyses, based on 73 apfu). Semseyite aggregates have the empirical formula (Pb8.72Fe0.14)8.86Sb8.42S20.73 (average of 11 analyses, based on 38 apfu).
Adaptaciones curriculares para mejorar el rendimiento académico en niños con NEE de Educación Básica
Authors: Guzmán Lucia Mirella Sanisaca , Mendoza Mario Napoleón Briones , Sarcos Elvira Armenia Játiva , Moya Gina Elizabeth Mera
Published: December 2021

La investigación tuvo como propósito principal proponer una guía de adaptaciones curriculares para mejorar el rendimiento académico de los estudiantes con NEE del Distrito 09D05C04, a partir de la caracterización, identificación y descripción de las diferentes estrategias específicas y diversificadas ya sea para la discapacidad permanente o transitoria. Este estudio se realizó con 81 educadores con el enfoque cuantitativo, diseño proyectivo, con una muestra no probabilística. La técnica empleada para la recolección de la información fue la observación sistematizada con el instrumento lista de cotejo; la guía de observación, estuvo compuesto de 24 ítems donde describía si tiene o no tienen los documentos legales. El instrumento no requiere de validación de expertos, puesto que la comprensión del mismo es para la autora. Los resultados fueron analizados e interpretados por el programa SPSS versión 2.5 para luego distribuirlos en tablas y figuras respectivamente, encontrando que aproximadamente un 93% de docentes (Tablas del 1 al 9) no cuentan con los documentos legales para la elaboración y uso de las adaptaciones curriculares, llegando a identificar la necesidad de la elaboración de una propuesta con estrategias específicas y diversificadas, adicionalmente,  incluir en la planificación el factor del entorno familia y la evaluación cuantitativa, para proporcionar la guía a los docentes del Distrito 09D05C04. Estos resultados llevaron a concluir que los docentes necesitan de un medio (Guía) que les permita hacer adaptaciones curriculares para mejorar el rendimiento académico en niños con NEE de Educación Básica.
Some Divisibility Properties of Lucas Numbers
Authors: ŞAHİN Adem , KARAGÖL Sadettin
Published: December 2021

The Lucas number sequence is a popular number sequence that has been described as similar to the Fibonacci number sequence. A lot of research has been done on this number sequence. Some of these studies are on the divisibility properties of this number sequence. Carlitz (1964) examined the requirement that a given Lucas number can be divided by another Lucas number. After that, many studies have been done on this subject. In the present article, we obtain some divisibility properties of the Lucas Numbers. First, we examine the case $L_{(2n-1)m}/L_{m}$ and then we obtain $L_{\left( 2n-1\right) m}$ using different forms of Lucas numbers.
Development and Evaluation of Nanoparticles Based Topical Gel Containing Antifungal Drug Fluconazole
Authors:   Department of pharmaceutics, Nargund College of pharmacy,Bangalore, Khanum Misbah
Published: December 2021

The objective of this work was to prepare Fluconazole nanoparticles, and then incorporated into the freshly prepared gel for transdermal delivery, reducing the oral side effects of the drug and forenhancing stability. Fluconazole is commonly used antifungal agents for the treatment of local and systemic fungal infections. In this study Fluconazole nanoparticles was prepared by using Eudragit RL 100 by nanoprecipitation method with different drugs to polymer (1:1, 1:2 and 1:3) and stabilizer (Poloxamer 188) ratios (0.5%, 0.75% and 1%) and evaluated for various parameters. Drug-excipients compatibility was performed by FTIR study. The particle size, polydispersity index, Zeta potential, % Entrapment efficiency and % drug content of all the formulations were found in the range of 16.8 to 48.9nm, 0.229 to 0.558, -11.6 to -26.6 mv, 28.41% to 95.78% and 59% to 97.38%. From SEM studies it was revealed that Fluconazole nanoparticles particles are spherical in shape and without any agglomeration. From the in-vitro drug release study, it was revealed that sustained release of same formulation last up to 12 hours. From the stability study, it was revealed that the F5 formulation was stable at 40°C ± 2°C /75% ± 5%RH and 4°C. The optimised formulation F5 was selected to prepare Fluconazole loaded nanoparticles based topical gels using different concentration of Carbopol 934 and 940 and characterized for pH, spreadability, drug content, viscosity and in-vitro drug diffusion. Among the five formulations, G5 was selected as the best formulation. The pH of all formulations was found near to the skin pH value. The in-vitrodiffusion study of Fluconazole gel (G5) showed 94.75%. The optimized formulation G5 was checked for mechanism and kinetics of drug release. It is found it following Zero order release and non-Fickian mechanism. The selected Gel formulation G5 was found to be stable at 40°C ± 2°C /75% ± 5%RH and 4°C, it is clear that the formulation did not undergo any chemical changes found more stable at room temperature
Criminal Liability Committed by Corporations for Environmental Damage as a Result of Forest and Land Fires (Case Study Case Number 59/PID). B/LH/2020/PN. RGT)
Authors:   Jakarta National Development University ", Azhari Teuku ,   Veteran"
Published: December 2021

The deforestation process that occurs in Riau is very worrying, forest and land fires are proof that environmental management and utilization are no longer reliable. These forest and land fires are proven to involve companies involved in the cultivation and utilization of forest products. For this reason, the corporation must be criminally responsible because UUPPLH No. 32 of 2009 has recognized the corporation as the subject of criminal law. Efforts to hold companies accountable aren't easy — many companies actually stop investigations because they don't have enough evidence. Therefore, the author wants to know the criteria of corporations that are said to commit forest and land fire crimes, as well as how the form of criminal accountability. This research method uses normative legal methods and sculptural approaches that are approaches through legislation. The results of the investigation, the criteria of the corporation to commit the crime of forest and land fires if it meets the elements in the preparation of articles of forest and land fires, namely land clearing by burning and exceeding environmental quality standards. The violation is committed by a person for work or other relationship reasons within the scope of the business entity. If the crime is committed by, for, or on behalf of a business entity, it shall be considered a corporate act. The form of corporate criminal liability in the criminal act of forest and land fires is preliminary, because the error lies with the corporate administrator (director) who is the mastermind or owner of control of the company's operational activities (Director Mind). Because in PP No. 4 of 2001 Article 13 that the director as the person in charge of all commercial activities whose business can cause damage and environmental pollution must comply with government regulation No. forest and land fires.
Biodiversity of Fishes of River Ecosystems of the Western Tyan-Shan
Authors:   Doctor of Philosophy in Biological Sciences, Institute of Zoology Uzbek Academy of Sciences, Tashkent, Uzbekistan, Mirzaev Ulugbek
Published: December 2021

The paper cites data on the biological diversity of fishes in the river ecosystems of the Western Tien Shan. Data on the diversity and distribution of species are presented and analyzed. The role of various factors affecting the variability of species numbers and their range is discussed, which is important for development of a number of measures on conservation of rare and vanishing fish species.
Rheumatoid arthritis associated with primary biliary cholangitis under treatment with biological drugs
Authors: Jones Xaviar Michael , Montiel Bertone Mariano , Savio Verónica Gabriela , Werner Marina Laura , Strusberg Ingrid
Published: December 2021

The therapeutic approach of patients with two or more autoimmune diseases is quite a challenge, especially when the treatment of one of them, can precipitate the progression of the other. Even though the association of rheumatoid arthritis (RA) and primary biliary cholangitis (PBC) is rare; when both coexist, the use of methotrexate and other hepatotoxic drugs should be used with caution. With a most widespread indication of biologic disease- modifying antirheumatic drugs (bDMARDs) some reports of patients with RA and PBC treated with etanercept, infliximab, rituximab, tocilizumab and abatacept have been published. We report a case series that includes 4 patients with RA and PBC treated with bDMARDs. This is the first report to describe two cases in which golimumab was used to control RA and the second to report patients who received adalimumab and abatacept. Three cases of patients treated with rituximab have been published to date. None of the patients of our report suffered a progression of their PBC; matter in fact, two of them showed an improvement in their biochemical parameters. PBC symptoms did not get worse in any of the patients. On the contrary, laboratory parameters improved in two of the four patients.
Rubens and rheumatoid arthritis
Authors: Leiber Vargas Caselles Alfredo , Fernández Ávila Diana Carolina
Published: December 2021

The study of baroque paintings, especially those of Flemish origin, makes it possible to show in some of their figures physical signs suggestive of disease. Peter Paul Rubens constitutes one of the maximum representatives of this artistic current. It is believed that Rubens suffered from rheumatoid arthritis (RA) and that he portrayed the development and progression of his own disease in several works of art. This article briefly recounts Rubens’ life and describes some of his works focused on the human figure with joint alterations that could correspond to an AR.
Cellulose-containing waste recycling using fungi
Authors: Fomenko I. A. , Tuchkova S. N.
Published: December 2021

Accumulation of plant waste is a serious environmental problem. Mushrooms with high cellulolytic activity can process it into valuable products that will be useful in solving various industries and agriculture problems. The enzymes of the cellulolytic complex include 1,4-β-D-glucan-4-glucanohydrolase, exo-1,4-β-glucosidase, cellobiohydrolase, β-glucosidase. 1,4-β-D-glucan-4-glucanohydrolases destroy β-1,4-glycosidic bonds within the chain of cellulose and lichenin polysaccharides. Exoglucanases destroy β-1,3- and β-1,4-glycosidic bonds at the end of the molecule. Cellobiohydrolases cleave β-1,4-glycosidic bonds to form cellobiose and glucose. β-glucosidase complete the process of destruction. Fungi with high cellulolytic activity include both representatives of the Ascomycota and Basidiomycota divisions. Ascomycete Chaetomium globosum produces endoglucanases of two families and 8 cellobiohydrolases. Myceliophthora thermophila also produces endoglucanases and cellobiohydrolases, the most abundant of which is Mt Cel7A. The fungus is a promising producer of thermostable enzymes. Trichoderma reesei has a long history of safe use as a source of highly active cellulolytic enzymes and other valuable metabolites. LPMOs of the cellulolytic fungus Thielavia terrestris are considered auxiliary enzymes, but can negatively affect the main enzymes of the complex. Irpex lacteus also produces LPMO and a complete cellulolytic enzyme complex. The cellulolytic activity of fungi and their ability to grow on cheap substrates can be used to bioconvert plant waste into valuable products. One of the ways to utilize them is to convert into compound feed with a high protein content through the use of starter cultures. The use of mushrooms will increase the content of protein and simple carbohydrates, enrich the feed with fats. Another method is to obtain cellulases, which are widely used in many industries. Thanks to the production of biodiesel and bioethanol from cellulose-containing raw materials it is possible to solve the problem of lack of fuel by replacing energy carriers from non-renewable energy sources with their environmentally friendly counterparts. They are less toxic than diesel and gasoline and are also made from renewable resources.
Dispersion of watermelon rinds as secondary raw materials in technologies of pectin-containing extracts and film structures
Authors: Meshcheryakova G. S. , Nugmanov A. H.-H. , Aleksanian I. Yu. , Maksimenko Yu. A. , Sokolova E. V.
Published: December 2021

The development of protective coatings based on pectin substances that serve as natural structure-forming agents developed from a secondary resource base is focused on removing a complex problem in the production of finished products by deep processing of basic raw materials and developing an original film material. At the same time, the technical result of obtaining pectin-containing film structures is their ability to protect food products from microbiological spoilage, natural losses during storage and the preservation of quality and safety indicators. An important preparatory procedure that determines the efficiency and intensity of extraction processes can be attributed to the operation of dispersing the feedstock, since it directly affects the size of the contact surface area of the phases involved in mass transfer. However, it is clear that the greater the degree of grinding, the higher the efficiency of the process, but an excessive increase can lead to additional unjustified energy costs and, as a result, to an increase in the cost of the finished products sold. In this regard, the purpose of the research is to analyze existing technologies for producing pectin-containing extracts, in which watermelon rinds can be used as secondary resources and to intensify the extraction process by conducting a rational preparatory procedure for grinding the raw materials. The object of the research are watermelon rinds as non-recyclable waste from processing watermelon raw materials. According to the obtained graphs, and taking into account the high rates of gelatinization of the obtained pectin extracts, it is possible to recommend a complex treatment of watermelon rinds, including, in addition to the operations of preliminary preparation of raw materials, ultrasonic exposure and acid hydrolysis, and it is desirable to use food acids, for example, acetic or citric, instead of aggressive sulfuric and hydrochloric acids. As a result of the study of the dispersed composition, it has been concluded that the average equivalent particle size of the dispersed raw materials does not exceed the recommended limits, that is, the result obtained can be considered acceptable.
Studying the possibility of using non-traditional vegetable raw materials of the Republic of Adygea in the production of functional antioxidant products
Authors: Skhalyakhov A. A. , Siyukhov Kh. R. , Tazova Z. T. , Lunina L. V.
Published: December 2021

In the last decade the attitude of socially active people to their own health has changed significantly. The desire to lead a healthy lifestyle forms consumers’ demand for proper balanced nutrition, products enriched with natural biologically active substances of unconventional plant materials, systematic consumption of which can not only reduce the risk of alimentary diseases, but also protect a person from oxidative stress, which is the predecessor of many serious illnesses. Among the wide range of chemical compounds that make up plant materials, a special place is occupied by compounds of antioxidant action, such as flavonoids, phenol carboxylic acids, vitamins C and E. The aim of the research was to study the qualitative composition and quantitative content of natural antioxidants in some types of medicinal and technical plant materials of the Republic of Adygea to determine the possibility of their use in the production of functional food products. The content of biologically active compounds that determine the antioxidant properties of plant materials was determined using «Kapel 105 «M» capillary electrophoresis system and JASCO 875-UV liquid chromatograph. Antioxidant activity was measured by the amperometric method with Tsvet Yauza-01-AA analyzer. According to the results of the research, it has been found that Echinacea purpurea herb (1,09 g / dm3) and walnut leaves (0,96 g / dm3) exhibit a high antioxidant activity (in terms of gallic acid), which is due to the high concentration of natural antioxidants of the phenolic type. Due to these properties this plant raw materials can be used as enriching ingredients for the production of various groups of food products for functional purposes.
Association of early donor chimerism status with survival outcomes in post allogeneic hematopoietic stem cell transplant patients of nonmalignant diseases
Authors: Sial Nadia , Ahmed Parvez , Feroza Hamid Wattoo  , Ali Nadir
Published: December 2021

Objective: To highlight the association of early donor chimerism status at 2nd month with various survival outcomes.
Method: The retrospective study was conducted at the Armed Forces Bone Marrow Transplant Centre, Rawalpindi, Pakistan, and comprised patient  data from January 2011 to July 2016. Data related to participants who underwent human leukocyte antigen-matched transplants for bone marrow failure syndrome and beta thalassemia major. Short tandem repeat-based polymerase chain reaction was used to assess donor chimerism status. Overall survival, disease-free survival, relapse-free survival, and graft versus host disease-free survival rates were noted. Data was analysed using SPSS 23.
Results: Of the 106, 64(60.4%) had bone marrow failure syndrome and 42(39.6%) had beta thalassemia major. The overall median follow-up was 13.53 months (range: 1.81-62.73 months). Early donor chimerism status was associated with overall survival (p=0.02) and disease-free survival (p=0.01). Mixed donor chimerism was less hazardous in terms of overall survival (p=0.04) and disease-free survival (p=0.02).
Conclusion: Early mixed donor chimerism contributed to optimal survival in nonmalignant disease.
Key Words: Hematopoietic stem cell transplantation, Nonmalignant diseases, Survival outcome, Conditioning regimen.
ONION PRODUCTION AND MARKETING SYSTEM IN BALOCHISTAN PROVINCE
Authors: Khan J. , Pasand S. , Tunio S. P. , Gadehi M. A. , Shahwani M. A.
Published: December 2021

In Pakistan, onion is one of the most grown commercial crops in the various parts of the country. The study was carried out through a primary data collection from various stakeholders to examine the status of onion production in Balochistan province. The average per acre cost of production, productivity, profitability, input output ratio were analyzed. Furthermore, find out the issues and constraints faced by onion growers and recommend policy guidelines for sustainable onion production and marketing in the study area. Costs have been broken down in a variable, fixed and opportunity costs (depreciation and opportunity) costs for production factors that are owned by the onion growers. While the variable cost was high from other costs, among them seed rate cost was high in the variable cost and in the lowest costs was recorded in chemical weedicide from other variable costs and fixed cost was nil due to relief from Balochistan government, whereas total cost of production and net income was Rs.82737 and Rs.75665 per acre respectively found in the study area.  Majority 67% seed dealers were reported that due to high ratio of population, more consumable, good seed quality, more benefit, short duration of time and more production of onion as the principal reason for increase seed suppliers over the past 5 years. Onion farmers must follow best methods in management and strive to adopt scientific guidance from local and other available sources, for example research stations, progressive producers and extension workers.
Homens de Mando: as redes de sociabilidades dos capitães-mores na capitania de Porto Seguro (1670-1682)
Authors: Santos Xavier Ana Paula
Published: December 2021

O presente artigo tem por finalidade principal analisar a atuação dos capitães-mores nas questões militares na antiga capitania de Porto Seguro de 1670 a 1682, bem como o impacto das ações na vivência dos índios e colonos. Busca-se compreender, desse modo, como eram os recrutamentos desses oficiais, as possibilidades de mobilidade entre os agentes, assim como seus mecanismos de promoção. Assim, sendo possível reconstruir o perfil e a inserção sociopolítica e econômica destes oficiais, analisando as formas de reproduções sociais por meio das quais buscavam um melhor posicionamento no seio da sociedade colonial. As informações encontradas em diferentes grupos de documentos passaram pela metodologia do método indiciário para perceber os pequenos vestígios deixados por estes indivíduos e as ligações nominativas, para compreender as relações estabelecidas por eles a partir dos nomes que os cercam, ambos desenvolvidos pela Micro-História. Possibilitando, assim, conhecer algumas estratégias traçadas por estes indivíduos, influenciando para que eles fossem vistos e permanecessem como homens detentores de mando. Por fim, é necessário compreender uma localidade a partir das especificidades do seu tempo e com isso se as nomeações para os cargos dos capitães-mores atendiam a esses requisitos, tendo as relações baseadas em interesses maiores, exemplo disso é o caso de algumas ascensões ao posto do capitão-mor, baseadas em conflitos e intrigas.
Competencias clave y patrimonio en educación primaria. Un análisis de la concepción del profesorado en formación
Authors: Moreno-Vera Juan Ramón , Ponsoda-López de Atalaya Santiago
Published: December 2021

La investigación que se presenta tiene como objetivo principal el análisis de las concepciones de los futuros docentes de Educación Primaria sobre la utilidad de la educación patrimonial a la hora de trabajar las competencias clave propuestas por el currículum. Para ello se diseñó, validó e implementó un cuestionario (escala Likert) entre 279 futuros maestros/as del grado de Maestro/a en Educación Primaria de la Universidad de Alicante cuyos resultados fueron analizados a través del paquete estadístico SPSS v24. Los resultados muestran cómo el alumnado considera el patrimonio un recurso válido para el trabajo de las diferentes competencias clave en el aula de Educación Primaria, si bien los futuros profesores lo consideran más adecuado para trabajar la conciencia y expresiones culturales y las competencias sociales y cívicas, mientras que el resto de competencias obtienen menores puntuaciones lo que indica, a modo de conclusión, que no se trabaja el patrimonio en un sentido holístico y transversal. Estos resultados ponen de manifiesto, por tanto, la necesidad de abordar la enseñanza a través del patrimonio desde un prisma amplio que tenga en cuenta algunas de sus principales potencialidades como es la transversalidad y la interdisciplinariedad, lo cual lo convertiría en un recurso de primer orden para abordar el tratamiento de las diferentes competencias claves.
INCORPORACIÓN AL MARCO NORMATIVO DEL NUEVO REGLAMENTO DE ACTUACIÓN Y FUNCIONAMIENTO DEL SECTOR PÚBLICO POR MEDIOS ELECTRÓNICOS, APROBADO POR REAL DECRETO 203/2021 Y SU IMPACTO EN EL PROCEDIMIENTO ADMI
Authors: RAMOS RAMOS ANA
Published: December 2021

El 2 de abril de 2021 es, sin duda, una fecha clave para el funcionamiento del sector público, ya que en coherencia con la disposición final séptima de la Ley 39/2015, entra en vigor el Real Decreto 203/2021, de 30 de marzo, por el que se aprueba el Reglamento de actuación y funcionamiento del sector público por medios electrónicos, que desarrolla tanto la Ley 39/2015, de 1 de octubre, del Procedimiento Administrativo Común de las Administraciones Públicas como la Ley 40/2015, de 1 de octubre, de Régimen Jurídico del Sector Público. El presente artículo analiza la incorporación de la vigente normativa al régimen jurídico administrativo y los principales puntos del Real Decreto 203/2021 a tener en cuenta en el procedimiento administrativo. Sin duda, traerá consigo un cambio definitivo del modelo administrativo de los próximos años.

2021eko apirilaren 2a, zalantzarik gabe, funtsezko data da sektore publikoaren funtzionamendurako;izan ere, 39/2015 Legearen azken xedapenaren zazpigarrenarekin bat etorriz, martxoaren 30eko 203/2021 Errege Dekretua indarrean sartu zen; horren bidez onartu zen Sektore publikoa bitarteko elektronikoen bidez jarduteko eta funtzionatzeko Erregelamendua, bai Herri Administrazioen Administrazio Prozedura Erkidearen urriaren 1eko 39/2015 Legea, bai Sektore Publikoaren Araubide Juridikoaren urriaren 1eko 40/2015 Legea garatzen dituena.
Artikulu honek aztertzen du indarreko araudia administrazio-araubide juridikoan nola txertatu den eta zein diren administrazio-prozeduran kontuan hartu beharreko 203/2021 Errege Dekretuaren puntu nagusiak. Zalantzarik gabe, datozen urteetako administrazio ereduaren behin betiko aldaketa ekarriko du horrek.

April 2, 2021 is unquestionably a key date in the functioning of the public sector since, in accordance with the seventh final provision of Law 39/2015, it marks the entry into force of Royal Decree 203/2021, of 30 March 2021, approving the Regulation on action and operation in the public sector by electronic means, which develops on both Law 39/2015, of 1 October 2015, on the Common Administrative Procedure of Public Administrations, and Law 40/2015, of 1 October 2015, on the Legal Regime of the Public Sector. This article analyzes the incorporation of the current regulations into the administrative legal regime, and the main points of Royal Decree 203/2021 to be taken into account in administrative procedure. This will unquestionably bring about a definitive change in the administrative model in the coming years.
ANÁLISE DO PERFIL SOCIODEMOGRÁFICO DE GESTANTE DE ZONA RURAL E URBANA DE UM MUNICÍPIO DA REGIÃO AMAZÔNICA
Authors: Maia Italo Jaques Figueiredo , Marrone Luiz Carlos Porcello , Martins Maria Isabel Morgan
Published: December 2021

A gestação é um momento importante na vida de toda mulher, onde acontecem diversas mudanças morfofisiológicas na vida desta gestante, o que torna necessário um acompanhamento mais peculiar e individual. Compreender as necessidades das gestantes de diferentes regiões facilita um melhor entendimento e mensuração das necessidades específicas destas gestantes. Objetivo: Analisar e comparar gestantes de zona urbana e rural de um município amazônico brasileiro em seu perfil sociodemográfico. Método: Uma pesquisa do tipo descritiva, exploratória e transversal. Foi realizada entrevista com gestantes que eram acompanhadas em seu pré-natal em um centro de saúde, onde foram questionadas a respeito de sua vida sociodemográfica. Resultado e Discussão: Mostram que 23 gestantes responderam a entrevista, a média de idade das gestantes ficou em 26 anos. Gestantes da zona rural (44,4%) gastam de 30 à 2h com tempo de deslocamento até o Centro de Saúde, e as da zona urbana (100%) não demoram mais que 30 minutos. Conclusão: Este estudo revelou que gestantes da zona rural moram mais em casas cedidas do que as de zona urbana, e que o poder econômico das gestantes de zona urbana é maior do que as de zona rural.
A Study about Brahmi (Bacopa monnieri) Preparation Steps on Its Saponin Quantity
Authors: Nichakool Bunyaporn , Jamphon Amporn , Pootang-on Yupa , Techakriengkrai Weerawan , Techakriengkrai Taweesak
Published: December 2021

Brahmi (Bacopa monnieri) is a medicinal herb containing bioactive compounds (Bacosides) in the saponin group that enhances memory and prevents dementia. Brahmi is not favored for cooking because it is very bitter. Nowadays, most people consume Brahmi as supplementary food, which makes it more expensive than consuming in food form, not getting fibers and other nutrients. Currently, there are only few studies that work to alleviate in Brahmi. Therefore, this study aimed to find out the saponin quantity in Brahmi after some pretreatments and the effect of these treatments on Bacosides and bitterness. Thus, suitable preparation steps for Brahmi have the highest remaining saponin quantity and are consumable. There were various techniques of preparation, depending on the concentration of salt used in crumpling and 1 time boiling of Brahmi to reduce its bitterness. The salt concentrations used in this study were 0, 10, and 20 % (w/w) compared with the fresh herb. The saponin quantity was analyzed by high-performance liquid chromatography (HPLC). The results showed that the total amount of saponin in boiled Brahmi that crumpled with 0, 10, and 20 % were significantly lower than fresh Brahmi (p < 0.05). Brahmi was crumpled with 10 % salt before boiling had the highest total saponin quantity of 2.69±0.02 g/kg of fresh weight and the highest tasting scores. Thus, the preparation of crumpling with 10 % salt before cooking, was suitable because consumers gained the highest saponin and accepted the taste of food containing Brahmi.

HIGHLIGHTS

Brahmi have many health benefits not only memory enhancer but also prevention of dementia

People used Brahmi as supplementary food because it is very bitter and not favored for cooking

Reduce the bitter with non chemical as crumpling with 10 % salt concentration before cooking was highest saponin and accepted the taste of food containing Brahmi
Gambaran Penurunan Nyeri Pada Penderita Low Back Pain Setelah Dilakukan Latihan William Fleksi : Literature Review
Authors: Setya Aditama M. Firnanda , Ersila Wahyu
Published: December 2021

AbstrakLow back pain merupakan gangguan pada tulang belakang yang dapat menyebabkan timbulnya nyeri sehingga menyebabkan gangguan fungsional yang akhirnya menghambat aktivitas sehari-hari.Penyebab low back pain yaitu faktor struktural akibat adanya luka pada tulang belakang, faktor psikologis seperti penyakit pada bagian organ dalam maupun organ reproduksi, kurang olahraga, dan faktor biomekanik akibat disfungsi pada sistem muskuloskeletal. Modalitas yang digunakan pada kasus low back pain yaitu terapi latihan william fleksi. Penelitian literature review ini bertujuan untuk mengetahui gambaran penurunan nyeri pada penderita low back pain setelah dilakukan latihan william. Pemilihan artikel pada penelitian ini menggunakan metode PICO. Penulisan artikel ini menggunakan penelusuran literature melalui google scholar (4) dan pubmed (1). Kriteria inklusi dan ekslusi sesuai dengan kata kunci, dipublish rentang waktu 2015-2020. Hasil literature review 5 artikel menunjukan bahwa jenis kelamin laki-laki mendominasi yaitu sebanyak 55,6% dengan rentang usia mulai dari 22 tahun-50 tahun dan penurunan nyeri pada penderita low back pain dengan rata-rata sebelum dilakukan latihan william fleksi 7,08 dan sesudah dilakukan latihan william fleksi 2,80 dengan selisih rata-rata 4,27. Latihan william fleksi mampu menurunkan nyeri pada penderita Low back pain. dasar tindakan dalam melakukan management fisioterapi pada masalah penurunan nyeri Low back pain..Kata Kunci: Latihan william fleksi, Low back pain, Nyeri.
Effect of plot size and plant spatial arrangement on the efficiency of family selection in sugarcane
Authors: De Moraes Aparecido , Henrique Silveira Mendes Matheus , Sérgio de Oliveira Leite Mauro , De Castro Carvalho Regis , Maria Avelar Gonçalves Flávia
Published: December 2021

The purpose of this study was to identify the ideal sample size representing a family in its potential, to identify superior families and, in parallel, determine in which spatial arrangement they may have a better accuracy in the selection of new varieties of sugarcane. For such purpose, five families of full-sibs were evaluated, each with 360 individuals, in the randomized blocks design, with three replications in three different spacing among plants in the row (50 cm, 75 cm, and 100 cm) and 150 cm between the rows. To determine the ideal sample size, as well as the better spacing for evaluation, the bootstrap method was adopted. It was observed that 100 cm spacings provided the best average for the stalk numbers, stalk diameter and for estimated weight of stalks in the stool. The spacing of 75 cm between the plants allowed a better power of discrimination among the families for all characters evaluated. At this 75 cm spacing  was also possible to identify superior families with a sample of 30 plants each plot and 3 reps in the trial.
Highlights

The bootstrap method was efficient to determine the ideal sample size, as well as the best spacing for evaluation.
The 75-cm spacing had the highest power of discrimination among families, indicating that this spacing is the most efficient in evaluating sugarcane families for selection purposes.
From all the results and considering selective accuracy as the guiding parameter for decision making, the highest values obtained considering the number of stalks and weight of stalks in the stools were found at the 75-cm spacing.
Prioritization of vigor QTL-associated genes for future genome-directed Vitis breeding
Authors: Hugalde Inés , Paolinelli Marcos , Agüero Cecilia B. , Riaz Summaira , Gómez Talquenca Sebastián , Walker M. Andrew , Vila Hernán
Published: December 2021

Vigor control in grapevine may become especially important under climate change. A better understanding of gene-phenotype relationships is required in order to exploit plant genomics for breeding purposes. This research aims to use quantitative trait loci (QTLs) for vigor identified in the progeny from a cross of Ramsey (Vitis champinii) × Riparia Gloire (V. riparia). Genes located 700 kb up and downstream from each QTL position were interrogated for functional enrichment through ShinyGO online tool, based on the gene ontology annotation of Vitis vinifera PN40024. Key biological processes like phloem and xylem development, cell cycle, response to hormones, amino acid transport, tissue development, sugar metabolism, nitrogen transport, and stress/immune responses, showed functional enrichment. Integral response to light and auxin might be required for fine molecular tuning of vegetative growth in Vitis. Fifty out of 1318 candidate genes were prioritized, reducing their amount to a manageable number of candidates for further directed breeding strategies.
Highlights

Plant vigor control may become especially important under climate change.

Genes from various vigor-related QTLs were interrogated for functional enrichment.

The analysis reduced candidate gene number based on marker proximity and functional enrichment, constituting a suitable shortcut for target-directed genome-guided breeding strategies.

Three TFs are strong candidates for targeted breeding: TIF - HY5, TIF - SUS1, TIF - VOZ1 potentially enhance growth by relating light response to hormone activation, and then to photosynthesis and morphogenesis.
Germination and development of M1 seedlings of two Selliera radicans Cav. accessions subjected to gamma radiation
Authors: Soto Fabián , Peñaloza Patricia , Oyanedel Eduardo , Schiappacasse Flavia , Durán Oscar , Vidal Alexis
Published: December 2021

Selliera radicans is a creeping plant native to Chile, New Zealand and Australia. It is increasingly used in the ornamental industry, and there is interest in breeding it to create commercial varieties. The aim of this study was to determine the effects of different doses of gamma radiation applied to the seeds on the germination and development of seedlings (M1) and the LD50 of two accessions of Selliera radicans for use in the induction of mutations. Seeds of the Vichuquén and La Serena accessions were exposed to 0, 100, 200, 300, 400, 500, 600 and 700 Gy from a 60Co source. Weekly germination percentages along with seedling numbers and lengths were recorded. Vichuquén seeds were more sensitive to this physical agent. The LD50 was 243.9 Gy for Vichuquén and 445.6 Gy for La Serena. Seedling lengths reached almost 4 mm for Vichuquén and 11.3 mm for La Serena at 12 weeks after sowing. Doses lower than 200 Gy are recommended since higher doses do not allow the development of seedlings to the extended cotyledon stage.
Highlights:

This is the first radiosensitivity study for the Goodeniaceae family and therefore for the Selliera genus.
This study shows the specific effect of gamma radiation at the level of germination and seedling formation according to accession of origin.
This study could be used for the genetic improvement of Selliera radicans via the induction of mutations.
Implementation of iceplant production under semi-controlled conditions
Authors: Rodríguez-Hernández María del Carmen , Garmendia López Idoia
Published: December 2021

Mesembryanthemum crystallinum is considered a drought and saline stress-tolerant plant with many biological activities that has been revalued as cool flavouring plant. The objective of this work was to assess optimum mode of cultivation of M. crystallinum to produce edible parts under greenhouse conditions. Therefore, three soilless media were evaluated: peat, vermiculite and hydroponic culture. Pot culture in peat did not result to be a good substrate for iceplant, with little biomass production. However, vermiculite and hydroponics allowed optimum growth of M. crystallinum, with a significantly greater yield in plants grown in vermiculite irrigated with nutrient solution. In fact, plants cultivated in vermiculite enhanced leaf area and leaf fresh weight, together with high foliar concentrations of N, Mg, Mn, Fe, Na, clorophylls and carotenoids. Furthermore, increased succulence and Na concentration of edible parts of glacier lettuce grown in vermiculite can offer more interesting taste, consistence and nutrient content for consumers.
Higlights

Hydroponic and vermiculite cultures led to optimum crystallinum growth.
Peat pot culture did not seem to be an adequate substrate to cultivate crystallinum.
Ice plants grown in vermiculite presented highest leaf fresh yield and high foliar N, Mg, Mn, Fe, Na, chlorophyll and carotenoid concentrations.
Implantation of corporate social responsibility measures in the horticulture in Mexico and Spain
Authors: Bañuelos Torrontegui Karina Adalessa , Avendaño Ruiz Belem , Martinez-Carrasco Pleite Federico
Published: December 2021

This work presents the results of a survey, following the Delphi methodology, to experts from the horticultural sector of Mexico and Spain. Interactions with experts have made it possible to identify relevant aspects where the level of consensus is high about the proliferation of Corporate Social Responsibility (CSR) initiatives in the export sector of both countries, standing out: the horticultural sector's leadership in the implementation of standards, which responds to the demand for destination supermarkets in the US and Europe, which despite their particularities, have similar dynamics. Not implementing is considered a risk factor; the implementations are positive actions, which enhance the reputation of companies. Agricultural companies that have a lack of business culture, ignorance, and high administrative burden limit their development, especially among smaller production companies. The greatest progress has been made in the area of labor and environmental practices, areas where consumer concern is growing. Despite CRS initiatives are not providing an immediate benefit to companies, strategic spending is valued. The research is completed with a SWOT analysis (Weaknesses, Threats, Strengths and Opportunities), providing a valuable ranking of great interest for the design of competitive improvements.
Highlights

Corporate Social Responsibility (CRS) measures in the horticultural activity are driven mainly for the Supermarkets Chains. There are other factors to implement it: gain competitive advantage, improve the reputation of the sector, stay in the market.
The Delphi Method is a useful instrument to identify advantages, limitations, and barriers to adopt food safety and Social Responsibility Standards in the global value chain in the agricultural sector.
The horticultural activity is adopting several CRS standards in order to stay in the market such as: GRASP, FAIR TRADE, SEDEX, SA 8000.
The Delphi Panel considers that the CRS standards and measures implemented improve the labor, environmental and human rights in the horticultural activity in Mexico and Spain.
The role of fuel prices in spatial price transmission between horticultural markets: empirical analysis from a developing country
Authors: Valdes Salazar Rodrigo Andres
Published: December 2021

This article aims to analyze how fuel prices impact spatial price transmission between two Chilean horticultural wholesale markets. We implement a regime-dependent VECM where price transmission parameters depend on dynamics imposed by a stationary exogenous variable (fuel price). We identified two price transmission regimes characterized by different equilibrium relationships and short-run adjustment processes. This implies that fuel prices affect price transmission elasticities and intermarket adjustment speeds. Our results show increasing marketing costs as farm to market distance grows. This impact depends on each product’s attributes.
Highlights

This article analyzes the effect of fuel prices on the price transmission mechanism between the most relevant Chilean horticultural wholesale markets.

A regime-dependent Vector Error Correction Model where price transmission parameters depend on fuel price was implemented.

Clear evidence of the role played by fuel prices for in horizontal price transmission between the wholesale markets considered in this study was found.
This situation supports the idea that regardless of quantities traded in regional markets, the major effect of price adjustment is a result of the high demand, distances and market concentration of a central market. This impact depends on each product’s attributes.
Space Industry Development: Opportunities and Challenging in Thailand
Authors: Sivaraks Jesada , Malisuwan Settapong , Kaewphanuekrungsi Wassana
Published: December 2021

Satellites are technology developed to be able to orbit in space utilizing Earth’s gravity. Therefore, Satellite technologies are suitable for long- distance communications and are used for various activities in many fields such as telecommunications, geological surveys, the military, research, agricultural planning, maps and urban planning, etc. Satellite technology is one of the most important technologies for the stability as well as advancement of the telecommunication infrastructure of a country. Technological advancement has caused satellite businesses to evolve rapidly as well as create a variety of new business opportunities. Nowadays, the space industry has become a point of interest for many sectors. In terms of communication, this has allowed us to access the internet in areas where it previously didn’t exist. There are many studies which discuss the barriers to connectivity across the world. One reason for this lies in a lack of economic viability when it comes to providing internet services in the support of terrestrial infrastructure. A possible solution to this problem is the development of air and space internet access using balloons, drones, or even satellites. However, many wonder what possible challenges would arise along with the possible legal limitations. Suffice it to say, there might be multiple technical and even operational limitations such as the possibility of property damage or even problems related to orbit. According to studies from various research institutes around the world the consensus is that the possibility of internet access all over the world would indeed greatly benefit humanity as well as bring various economic and social benefits. In this paper, we will discuss the current state of things. We will also discuss the future of space industries around the world including in Thailand. We will then study the possibility of providing space-based internet services and the various aspects of that possibility. We will take a look at expert interviews, literature reviews, as well as study various articles from both domestic and international space and technology ventures that experienced development issues.