bluuebunny/crossref_metadata_2025 huggingface dataset:
ANÁLISE DE CUSTOS E DESPESAS DE UNIVERSIDADES FEDERAIS BRASILEIRAS DURANTE A PANDEMIA DE COVID-19
Authors: Teixeira Albino Lara , Moreira Ney Paulo
Published: June 2024

Considerando as dificuldades enfrentadas pelo setor educacional brasileiro devido a restrições orçamentárias, particularmente no âmbito do ensino superior, e os desafios causados pela pandemia e consequente isolamento social, este estudo se propôs a investigar se houve alterações nos gastos das universidades federais brasileiras após o surgimento da pandemia de COVID-19. A pesquisa adotou uma abordagem quantitativa, descritiva e documental, analisando Relatórios de Gestão das universidades e dados fornecidos pelo Tribunal de Contas da União (TCU). O período de análise abrangeu os anos de 2017 a 2022, com o objetivo de comparar os três anos que englobaram a pandemia (2020 a 2022) com os três anos anteriores (2017 a 2019). Três variáveis foram estudadas: Custo Corrente por Aluno Equivalente, Despesas Correntes e Despesas de Capital, levando em consideração os valores liquidados. A análise dos dados amostrais utilizou estatísticas descritivas, incluindo valores mínimo, máximo, média, mediana, desvio-padrão e coeficientes de variação. Além disso, o Teste de Wilcoxon foi empregado para identificar diferenças estatisticamente significativas entre as variáveis antes e durante a pandemia. Os resultados revelaram diferenças significativas entre os períodos estudados, com uma redução em todas as variáveis após o início da pandemia, sugerindo uma diminuição nos custos por aluno e nos investimentos das universidades federais brasileiras durante esse período.
Review Article: Importance of TQM And Business Excellence Models With Continuous Improvement Implementation of Initiatives And Sustainable Business Results in the UAE Organization
Authors: Almessabi Naof , Alansaari Khadija , Aldhafairi Aaesha
Published: June 2024

Purpose: This review article is to investigates the models of business excellence along with Total Quality Management (TQM) in healthcare specifically. It also illustrates how these models contribute to maintaining sustainability. Generally, total quality management provides a respected environment for patients, staff, and procedures. Moreover, EFQM and MBNQA are promoting the full frameworks in terms of satisfaction, strategies, and resources. While Sigma and lean methodology are crucial for the improvement and reduction of waste. Furthermore, a continuous improvement approach is used to improve both processes and services in the organization.  
Methodology: A comprehensive search by use of secondary data collection “Google Scholar”, search terms include “TQM”, “Continuous Improvement”, “Business Excellence”, and “Sustainability”. Most of the results have been filtered within studies published between 2020 and 2024, our references are matches with cited articles. In this review article, Medcare Medical Group has been chosen as a leading healthcare in the UAE providing health service at a high-quality level. TQM and business excellence models were involved in Medcare Medical Group to foster efficiency.
Findings: The review article has mentioned the importance of TQM and business excellence in healthcare particularly, the reflection of these models towards patient focus and the implemented strategies to maintain with changes.
Unique Contribution to Theory, Practice and Policy: A feedback collection provides future guidance for patient and employee engagement and introduces AI in healthcare strategies to target ethical issues.
Gobierno, democracia y ciudadanía universitaria en Argentina- estudio sobre las Universidades Públicas
Authors: Falcon Paulo
Published: June 2024

Este ensayo se inscribe en la inquietud de abordar una reflexión sobre la Universidad pública argentina, su diseño institucional y organización democrática y desde allí enfocarnos en el análisis del concepto de ciudadanía desde la perspectiva política, de manera de profundizar en los aspectos centrales de la participación ciudadana y representación del demo universitario en los espacios de cogobierno universitario.  En este punto es en el cual nos detendremos para analizar cómo y de qué manera la organización universitaria y su democracia, hacen al reconocimiento de los derechos ciudadanos de los actores universitarios colectivos e individuales en el juego de pertenencia. La metodología empleada para la construcción de este ensayo reflexivo responde a una revisión bibliográfica, de tipo descriptivo. Donde se revisaron diferentes documentos que sustentan la constitución y funcionamiento de las universidades públicas de Argentina. En conclusión, se puede afirmar que en particular la democracia universitaria necesita que los sujetos históricos que imaginen y deseen democracia, que se organicen y luchen por ella, que la constituyan en las condiciones académicas, científicas, culturales y políticas existentes. Sin duda, el legado reformista más trascendente es como lo hemos definido la incorporación de la política en clave democrática como medio para la democratización de las nuestras Casas de Altos Estudios.
Legislative Data Archiving and Records Keeping System
Authors: Parreño Jonas D. , Tudara Jan Mari , Soberano Kristine
Published: June 2024

This study focuses on the importance of records management and data archiving of the Legislative office of the LGU of Hinoba-an. A key element of modern governance is the legislative data archiving and record keeping system, enabling effective storage, management and access to legislation. LEDARKS is a central repository of legislative documents, including legislative acts, statutes, committee reports and meeting minutes, at all levels of government. The LEDARKS system ensures a systematic organisation and indexing of legal data, allowing rapid retrieval and analysis based on advanced database technologies and standardised metadata schemas. The development and implementation of LEDARKS require careful consideration of technical, legal, and policy challenges. In order to ensure the effectiveness and sustainability of LEDARKS initiatives, it is necessary to address issues like data privacy, security, interoperability and funding. Moreover, in order to optimise the LEDARKS systems and adapt them to the evolution of legislation and technological developments, ongoing research and evaluation is needed.
Poverty, Social Injustice, Religion and Insecurity in Nigeria: The Imperative of Essencism as A Philosophy Towards The Restoration of Democratic Values
Authors: Ekanem Professor Samuel Asuquo , Emejulu, PhD Jennifer
Published: June 2024

Despite unbroken democratic governance in Nigeria in the last twenty years, there has been an upsurge in poverty, social injustice, religious violence and insecurity. The logic that democracy is the government of the people, by the people and for the good of the people, which serves as a mechanism for the promotion of socio-economic development, peace stability and mass participation of the people in their affairs tends to be invalidated in Nigeria. It is reasoned that as the world headquarter of poverty, insecurity remains a constant decimal in Nigeria. This is because poverty breeds insecurity and an idle mind is the devil’s workshop. This paper analysis the correlations between poverty, social injustice, religion, and insecurity in Nigeria. It contends that violent conflicts characterize Nigerian democracy, and threatens the stability of governance institutions, promotes insecurity and creates the vicious cycle of poverty, and violent crimes in the country. This makes it difficult for the government to discharge its primary function of providing security of lives and property. The paper sees Boko Haram, banditry and kidnapping as socio-religious phenomenon that portray the socio-economic, political and ethnic problem that emerged due to bad leadership and governance. Consequently, Boko Haram and bandits have expanded their frontiers beyond Nigeria to other neighbouring countries. The theoretical framework of this paper is that insecurity as typified by Boko Haram, banditry and kidnapping have their roots in poverty and social injustice, which characterized the country’s governance system. It argues that corruption, human rights violations, marginalization, and other political vices that characterize state institutions and governance system can be eradicated through the educational system that is anchored on Essencism as a philosophy. This philosophy will through the educative process liberates the minds of the citizens, and implant in the citizens ethical values that will be presented as national ethics.
Confidence Intervals for the Ratio between Two Means of Birnbaum-Saunders Distributions
Authors: Ratasukharom N. , Niwitpong S. A. , Niwitpong S.
Published: June 2024

In this study, we introduced several methods to estimate confidence intervals for the ratio between means of Birnbaum-Saunders (BirSau) distributions. These methods encompassed the generalized confidence interval (GCI), bootstrap confidence interval (BCI), percentile bootstrap confidence interval (PBCI), Bayesian credible interval (BayCrI), and the highest posterior density (HPD). We conducted a Monte Carlo simulation to assess their performance, focusing on coverage probabilities and average widths. The simulation results revealed that the HPD method consistently delivered strong results for small and medium sample sizes across various scenarios. However, in the case of larger samples, the BCI method emerged as the most effective option. It was observed that as the sample size increased, the average widths of the proposed confidence intervals tended to decrease. Furthermore, we applied these methods to establish confidence intervals for the ratio between the means of wind speed datasets originating from two separate industrial regions in Thailand: Samut Prakan and Rayong province. The results obtained from this real-data application closely aligned with the findings derived from our simulation results.
Encryption and Decryption Using Decomposition of Complete Graph K3(6n+1)
Authors: Beaula C. , Venugopal P. , Sujaudeen N.
Published: June 2024

Encryption and decryption are the two processes in the cryptosystem that ensure the safe transfer of data or sensitive information. Apart from classical mathematics, graph theory techniques are employed nowadays to construct a strong cryptosystem. This paper uses graph techniques such as decomposition and labelling to encrypt and decrypt an alphanumeric string of length 8. The novelty of this paper is the introduction of (S9,C3)
-multi-decomposition and a new labelling technique - anti-magic decomposed labelling, which is applied in the cryptosystem.
Türkiye’de Fundafobinin İslamofobi’ye Dönüşümü ve Medyanın Rolü
Authors: Gür Ali
Published: June 2024

Batı dünyasında İslamofobi tarihsel teo-politik İslam karşıtlığı, yabancı düşmanlığı, ırkçılık ve radikalizm korkusu üzerinden geliştirilirken Türkiye’de ise basit bir kavram dönüşümüyle irtica ve şeriat korkusu aynı işlevi görmektedir. Bir nesilde kavramsal değişim olarak değerlendirilebilecek bu durum daha sonraki nesillerde zihinsel değişim ve dönüşüme yol açabilmektedir. Türkiye’de fundafobi ve bunun neticesinde yükselen bir İslamofobi’nin ve buna reaksiyon olarak oluşan laikofobinin varlığı bir realitedir. Medya da tüm organları ile bu karşılıklı çatışmayı beslemektedir. Ancak her iki tarafın da eylem ve söylemlerindeki aşırılıklar medyaya malze me oluşturmaktadır. Seküler laik Türkiye Cumhuriyeti’nde de yıllardır yükselen fundafobi ve gittikçe derinleşen bir İslamofobi’den söz edilmesine rağmen Batı kaynaklı fundafobi ve İslamofobi üzerine çok sayıda çalışmalar yapılırken Türkiye’de gelişen fundafobi ve İslamofobi üzerine fazla çalışma bulunmamaktadır. Kapsamlı literatür taraması üzerine yapılan bu çalışmada İslam dünyasının kendi içindeki fundafobiyi yeterince tartışmadığı için İslamofobi’ye nasıl dönüştüğüne dikkat çekilerek Türkiye’de İslamofobi’nin oluşum süreci ve medyanın rolü ele alınmaktadır. Müslüman toplumlarda da fundafobi gibi farklı kavramlar üzerinden İslamofobi’nin reaksiyoner olarak yükseldiği ve bunun toplumsal ayrışmaya zemin hazırladığı görülmektedir.
DESCRIPCIÓN DE EVENTOS ADVERSOS ASOCIADOS A LA VACUNA SARS- COV-2 (CHADOX1-S) RECOMBINANTE, COMO DOSIS DE REFUERZO PARA PREVENIR COMPLICACIONES DE LA COVID 19: UN ESTUDIO TRANSVERSAL.
Authors: Endara Edison , Vásconez Oswaldo , Patajalo Sheila , Suarez Ruperto , Rodríguez Santiago
Published: June 2024

Introducción En el contexto actual, los Eventos Supuestamente Atribuibles a la Vacunación o Inmunización (ESAVI) representan una preocupación constante. Este estudio se propuso identificar los ESAVIs vinculados a la tercera dosis de refuerzo con AstraZeneca (ChAdOx1-S) en el personal de un Hospital de Referencia en Quito, Ecuador. El objetivo principal fue prevenir complicaciones relacionadas con la COVID-19. Materiales y métodos Se llevó a cabo un estudio descriptivo transversal que incluye como participantes a los individuos, que forman parte de la institución, La participación se logró mediante una encuesta anónima en formato digital que constaba de 15 preguntas. Este instrumento permitió obtener información sobre las características de la muestra, los ESAVIs y el tiempo de aparición de estos después de la administración de la dosis de refuerzo. Resultados Un total de 115 individuos recibieron la tercera dosis de refuerzo, con una edad media de 41.9 ± 11.2 años y una representación del 72.2% de mujeres. Se reportaron ESAVIs en el 81.7% de los participantes. Los síntomas sistémicos más comunes incluyeron dolor muscular, fiebre y escalofríos, mientras que los síntomas locales predominantes fueron dolor y eritema en el sitio de punción. Conclusiones Los ESAVIs asociados con la vacuna AstraZeneca son frecuentes y generalmente leves. Los resultados sugieren que las dosis de refuerzo podrían ser cruciales para el control de la enfermedad. Se destaca la importancia de mantener una vigilancia continua para la detección temprana de nuevas reacciones adversas.
FRECUENCIA Y CARACTERÍSTICAS CLÍNICAS DE PACIENTES CON HEPATITIS AUTOINMUNE. ESTUDIO DESCRIPTIVO OBSERVACIONA
Authors: Ramon Juan Carlos , Montenegro Lisseth Alexandra , Reinoso Layla Viviana , Montenegro Oliver Esteban , Sangurima William Miguel , González Dominguez Camila , Hernández Paladines Joselyn , Castillo Espinoza Paul , López Guillermo , González Eduardo , Cordero Juan , González Domínguez Esteban
Published: June 2024

Introducción En la actualidad, se observa una amplia diversidad clínica en la forma en que se manifiesta la hepatitis autoinmune (HAI). Debido a la ausencia de características distintivas en los exámenes de diagnóstico, esta enfermedad suele considerarse poco común y a menudo no se diagnostica correctamente. Objetivos Determinar la frecuencia y características clínicas de pacientes con hepatitis autoinmune atendidos en el hospital de Especialidades José Carrasco Arteaga en el periodo Enero-2017 al Diciembre-2021. Metodología Se llevó a cabo un análisis descriptivo y retrospectivo en pacientes diagnosticados con Hepatitis Autoinmune. Se utilizó la información recopilada de forma anónima de la base de datos del hospital, utilizando formularios, y se creó una matriz en Excel con los datos. Estos datos fueron analizados utilizando el software estadístico SPSS versión 23. Resultados Del conjunto de casos recopilados con el código CIE 10 (K75.4), el 36% de la muestra (n=88) fue confirmado como Hepatitis Autoinmune (HAI) definitiva después del tratamiento, siguiendo los criterios de inclusión y exclusión. En este grupo, la mayoría de los casos corresponden a mujeres (85%). La forma de presentación más común de la HAI fue la crónica (39%), a menudo asociada con hipotiroidismo. Los síntomas más significativos fueron dolor abdominal (78%) e ictericia (54%). El síndrome de superposición se observó en el 26% de todos los pacientes. Los hallazgos inmuno histológicos predominantes fueron la presencia de anticuerpos antinucleares (83%) y anticuerpos antimúsculo liso (20%), así como la presencia de hepatitis de interfaz (36%). Las terapias recomendadas para estos pacientes incluyeron terapia combinada inicial (56%) y tratamiento inmunomodulador de mantenimiento (50%). Conclusión En la muestra analizada, se observa una incidencia elevada de Hepatitis Autoinmune (HAI), siendo más predominante en el sexo femenino; y la forma de presentación más prevalente fue la crocina, con características clínico-epidemiológicas que son similares a las reportadas en otros estudios.
TRANSLACIONALIDADE
Authors: Possa Marroni Norma , Marroni Claudio Augusto
Published: June 2024

A translacionalidade refere-se à aplicação prática e efetiva de descobertas científicas na pesquisa básica para o contexto clínico ou na prática clínica para benefício direto dos pacientes. Esse processo visa traduzir o conhecimento científico em avanços concretos que melhorem diagnósticos, tratamentos e cuidados médicos. A translacionalidade na pesquisa em saúde desempenha um papel importante, conectando a pesquisa básica com as aplicações clínicas.
Artificial Intelligence in Industry 4.0
Authors: Sheshadri Thejasvi
Published: June 2024

Many industry sectors have been pursuing the adoption of Industry 4.0 (I4.0) ideas and technologies, which promise to realize lean and just-in-time production through digitization and the use of smart machines. This shift is driven by technological advances, including Artificial Intelligence (AI) and machine learning, sensor networks and Internet of Things technologies, cloud computing, additive manufacturing, and the availability of large amounts of data that can be exploited by these technologies. However, the adoption of AI technologies for I4.0 varies considerably among industry sectors. This article complements broader reviews of I4.0 by examining the specific applications of AI. The recent White House report on Artificial Intelligence (AI) (Lee, 2016) highlights the significance of AI and the necessity of a clear roadmap and strategic investment in this area. As AI emerges from science fiction to become the frontier of world-changing technologies, there is an urgent need for systematic development and implementation of AI to see its real impact in the next generation of industrial systems, namely Industry 4.0. Within the 5C architecture previously proposed in Lee et al. (2015), the capacity to act specifically while addressing the ideal principle of artificial intelligence is solving the problem and achieving the objective. Finally, the paper identifies and discusses significant applications of AI for Industry 4.0.
Optimization of Medium Components and Genes Expression Involved in IAA Biosynthesis by Serratia plymuthica UBCF_13
Authors: Yusfi Liza Aulia , Tjong Djong Hon , Chaniago Irawati , Andini Zetrya , Jamsari Jamsari
Published: June 2024

Serratia plymuthica UBCF_13 produces the maximum level of indole-3-acetic acid (IAA) in yeast mannitol medium. However, the impact of medium ingredients on gene expression and metabolites related to IAA synthesis remains unclear. Therefore, Quantitative Reverse Transcription Polymerase Chain Reaction (qRT-PCR) was used to assess the effects of culture medium optimization components on the genes involved in IAA production. High-Performance Liquid Chromatography (HPLC) has been employed to investigate the impact of medium constituents on the metabolites associated with the biosynthesis of IAA. The highest IAA production was found in sucrose and yeast extract as the carbon and nitrogen sources (134.6 µg/mL). It was also discovered that calcium carbonate and magnesium sulfate are significant inorganic salts for UBCF_13 in the production of IAA. Most genes showed higher levels of expression when sucrose was used as the carbon source, including ipdC, nthA, puuC, amiE, oxdA, tyrB and nthB. Furthermore, the expression of tyrB, puuC, DDC and oxdA was upregulated in response to calcium carbonate, while puuC, nthA, nthB and amiE expression levels were elevated in the presence of magnesium sulfate. Indole-3-acetamide (IAM) was identified with HPLC as an intermediate product in several optimized culture media, with the highest IAA concentration (429.79 µg/mL) which was observed in yeast sucrose medium. Thus, sucrose played a pivotal role in IAA biosynthesis, and yeast sucrose medium supplemented with complete inorganic salts emerged as the optimal medium for IAA production by UBCF_13.
HIGHLIGHTS

This is the 1st study to evaluate the effect of each medium culture component on the expression of IAA synthesis genes in bacteria
The expression of several IAA synthesis genes (amiE, nthA, oxdA, tyrB, nthB, puuC and ipdC) was upregulated by using sucrose as the carbon source
Magnesium sulphate and calcium carbonate were shown to have a significant influence on IAA production, which also increased the expression of several IAA synthesis genes in UBCF_13
The increase in the expression of genes linked to the IAM pathway (nthA, nthB and amiE) and the identification of IAM as the only intermediate in the extract of optimum medium culture suggest that UBCF_13 may use the IAM pathway to synthesize IAA
It was discovered that sucrose and yeast extract with inorganic salts (dipotassium phosphate, magnesium sulphate, sodium chloride and calcium carbonate) were the optimal medium composition to produce IAA by UBCF_13

GRAPHICAL ABSTRACT
Effects of Cultivation Factors on Indigo Dye Yield in Indigofera Plants
Authors: Thosaikham Witchapol , Sakong Pornkamon
Published: June 2024

This research investigated the local wisdom of Sakon Nakhon province, Thailand, on cultivating Indigofera plants for optimal natural indigo dye yield. Focusing on Indigofera suffruticosa Mill. and Indigofera tinctoria L., the study explored the impact of pod development stages and harvesting time on dye yield. The findings showed that harvesting at the brown pod stage (18 - 20 weeks) and early morning (6:00 a.m.) yielded the most dye. Additionally, the study compared the Indigofera plants cultivation under 100 % and 60 % sunlight exposure, demonstrating that full sunlight significantly increased dye yield. Moreover, Indigofera suffruticosa Mill. gave significantly more indigo dye yield than Indigofera tinctoria L. (p < 0.05). This investigation, therefore, underscores the value of incorporating local knowledge into optimal cultivation practices for enhanced indigo production. However, further research should delve into additional factors, such as soil composition, fertilizer regimes and the genetics of the Indigofera plant.
HIGHLIGHTS
          This research investigates factors affecting natural indigo dye yield in Indigofera suffruticosa Mill. and Indigofera tinctoria L., the dominant species in Sakon Nakhon province, Thailand. Integrating local knowledge with multidisciplinary research, the study advances natural indigo dye production, offering insights for optimizing yield and promoting sustainable practices. This collaboration enriches understanding and fosters innovative Indigofera cultivation methods, marking a significant step forward in the field.
GRAPHICAL ABSTRACT
Comparative Studies of Two Indonesian Medicinal Plants, Bidara Upas (Merremia mammosa Lour. Hall.f) and Adas (Foeniculum vulgare Miller): Antioxidant, Antidiabetic, and Antimicrobial Activities
Authors: Fajar Mohamad , Safriansyah Wahyu , Muhajir Muhamad Imam , Maharani Rani , Supratman Unang
Published: June 2024

Bidara upas (Merremia mammosa) and adas (Foeniculum vulgare Miller) are 2 medicinal plants that grow abundantly in Indonesia. This study investigated the chemical composition and biological activity of M. mammosa and F. vulgare. Phytochemical screening was conducted on both plants. However, only the essential oil of F. vulgare was analyzed for GC spectra. A total of 23 compounds were identified from the essential oil of F. vulgare, with anethole being the main constituent (79.02 %). The extract of M. mammosa had a higher total phenolic content (TPC) and total flavonoid content (TFC) of 50.241 ± 0.012 mg gallic acid equivalent (GAE) per gram extract and 53.968 ± 0.742 mg quercetin equivalent (QRE) per gram extract, respectively. In the DPPH antioxidant test, the IC50 value indicated that M. mammosa extract had better activity than F. vulgare, with an IC50 of 89.139 ± 0.189 μgmL−1. This is supported by the TAC (Total Antoxidant Capacity) and Reducing Power Hexacyanoferrate (III) values, which also show a better antioxidant potential in M. Mammosa than in F. vulgare. In addition, M. mammosa has been shown to have an IC50 value of 2.215 ± 0.015 mgmL−1 against α-amylase inhibition, which is slightly different from F. vulgare with an IC50 value of 2.467 ± 0.025 mgmL−1. Overall, the antimicrobial activity of F. vulgare and M. mammosa was found to be resistant against S. mutans bacteria. The ethanol extract of F. vulgare was more potent against gram-positive bacteria and the essential oil was only effective against fungi. On the other hand, the ethanol extract of M. mammosa and the combination of their ethanol extracts showed no significant activity against bacteria and fungi. The combination of water extracts is most effective against 2 microbes, namely S. epidermis and E. faecalis with MIC 7.81 and 3.91 mgmL−1.
HIGHLIGHTS

The chemical composition of vulgare essential oil was characterised by GC-MS following experimental hydrodistillation.
The ethanol extract of mammosa exhibited superior activity towards antioxidant and alpha-amylase inhibition compared to the ethanol extract of F. vulgare.
The combination of aqueous extracts of mammosa and F. vulgare only showed activity against S. epidermis and E. faecalis.
Our findings reveal that mammosa exhibited some promising antioxidant properties, while F. vulgare demonstrated some potential for antimicrobial activity.

GRAPHICAL ABSTRACT
Variability of Physicochemical Database and Trypsin Inhibitory Activity of Komak (Lablab purpureus (L.) Sweet) Beans with Distinct Colors
Authors: Werdiningsih Wiharyani , Utami Tyas , Rahayu Endang Sutriswati , Setyaningsih Widiastuti
Published: June 2024

Komak (Lablab purpureus (L.) sweet) is a highly productive plant used for sustainable cultivation. However, beans are currently underutilized. A complete database including physicochemical characteristics is important for developing new foods derived from komak beans. This study aimed to determine the physical (weight, dimensions and color) and chemical (macromolecules, amino acids, sugars, minerals, phytic acid, tannin and volatile compounds) profiles, as well as the trypsin inhibitory activity of different varieties of komak beans, viz. white and black beans. The levels of the studied parameters differed significantly (p < 0.05) between the beans. However, the common profile of komak beans was characterized by a moderate level of protein (26 %), high carbohydrate (66 %) and low fat (2 %), with a weight ranging from 25 to 45 g and low anti-nutritional factor expressed as trypsin inhibitory activity (2 TIU/mg).  Additionally, analytical results using HS-SPME-GC/MS revealed that 1-octen-3-ol and benzyl alcohol were the main unpleasant volatile compounds produced upon heating beans. The major mineral compound in black beans is potassium, whereas the white variety contains higher amounts of magnesium, calcium and iron. Interestingly, both beans provided favorable compounds contributing to the umami taste, as the most dominant amino acids were glutamic and aspartic acids. Finally, as white beans were lower in antinutritive compounds (phytic acid and tannin), this measure may encourage further studies to expand the development of this variety to promote underutilized beans as alternative food sources.
HIGHLIGHTS

Komak is a productive and sustainable crop with underexploited beans
The 2 types of komak beans were medium-sized, containing moderate protein, high carbohydrates, low fat and low trypsin inhibitory activity
1-Octen-3-ol and benzyl alcohol were the major unpleasant volatile compounds produced by the beans
White beans have high magnesium, calcium and iron; black beans are primarily rich in potassium
White beans had less anti-nutritive phytic acid and tannin than black beans

GRAPHICAL ABSTRACT
Transcriptome Analysis of Drought-Tolerant Mechanisms in Mutant Chili
Authors: Matmarurat Gadewara , Chutinanthakun Katharat , Juntawong Piyada , Khamsuk Ornusa
Published: June 2024

Drought is a natural disaster that negatively impacts agricultural crops. Understanding the mechanisms of water deficit response is key to improving drought-tolerant crops. This study focused on comprehending the drought-tolerant mechanisms of a mutant chili, CaWDT-2, by investigating its physiological phenotypes and gene expression under PEG-induced drought condition compared to Tavee 60 as the original cultivar. Chili physiological status was monitored by shoot height, root length, leaf number, leaf area, shoot mass and root mass at 10 d after drought initiation. Relative water content (RWC), malondialdehyde (MDA), proline, soluble sugar and sucrose were measured during drought and after recovery. Transcriptome analysis using sequencing of RNA (RNA-seq) was employed to examine gene expression profiling under drought for 24 h. Results revealed diverse changes in physiological mechanism in response to drought between CaWDT-2 and Tavee 60 cultivars. Comparative transcriptomic analysis is helpful in understanding the differences in drought tolerance mechanisms between 2 crop varieties. Major differences that emerged from the physiological and transcriptomic analyses included drought-stressed injury level, proline accumulation, root cell wall adaptation, ABA biosynthesis, stress detoxification, heat shock proteins and transcription factors. Our data will contribute to further research in developing drought-tolerant crops. An improved understanding of drought tolerance mechanisms will enhance agricultural resilience and mitigate the impact of drought on crop yield.
HIGHLIGHTS

CaWDT-2, a drought-tolerant chili, could recover after exposure to a 10-d, 15 % PEG-induced drought, while Tavee 60, a drought-sensitive chili, could not
Physiological studies indicate that CaWDT-2 displayed higher tolerance to drought than Tavee 60
The roots of CaWDT-2 exhibited distinct drought-tolerant mechanisms at the gene expression level compared to Tavee 60 roots 24-h after water deficit
Comparative transcriptomic analysis is helpful in understanding the differences in drought tolerance mechanisms between CaWDT-2 and Tavee 60

GRAPHICAL ABSTRACT
“Vida, palavra-chave”
Authors: Rogowski Pozzo Renata , Tornquist Carmen Susana
Published: June 2024

Luiz Fernando Scheibe é geólogo formado pela Universidade Federal do Rio Grande do Sul em 1964 e concluiu o doutorado em Ciências (Mineralogia e Petrologia) pelo Instituto de Geociências da Universidade de São Paulo em 1986. Atualmente é professor voluntário da Universidade Federal de Santa Catarina, atuando nos Programas de Pós-Graduação em Geografia e Interdisciplinar em Ciências Humanas, com ênfase em Geoecologia e Hidrogeologia. Coordena em Santa Catarina o projeto Rede Guarani/Serra Geral. É professor emérito da UFSC, título concedido em dezembro de 2012.
 
Em uma tarde da primavera com chuva miúda, em 2023, o Professor Scheibe recebeu em sua residência, em Florianópolis, as professoras Carmen Susana Tornquist e Renata Rogowski Pozzo, do Programa de Pós-graduação em Planejamento Territorial e Desenvolvimento Socioambiental da Universidade do Estado de Santa Catarina, para uma entrevista que se desdobrou naturalmente de questões ambientais mais específicas que tocam o ofício do geólogo para o tema da vida no planeta, que envolve seu engajamento político claro com as lutas ambientais, indígena e populares, em Santa Catarina e na América Latina. Nos últimos anos, dedicou-se também a uma campanha contrária à extração do “gás de xisto” por fraturamento hidráulico (Fracking) no Brasil, sobre a qual pode-se consultar artigo publicado em 2013.[1] Na entrevista, o professor afirma que a água é o único mineral realmente essencial para a vida, e questiona: a quem servem os recursos minerais? A fala deste geólogo com rara formação científica e técnica e forte engajamento com as causas ambientais e populares expressa, de forma original, seu olhar matizado pelas leituras de Josué de Castro e Milton Santos. Esta entrevista amplia nossos horizontes sobre as possibilidades de uma economia dos recursos minerais para a vida.
 
[1] Xisto: implicações econômicas e ambientais: entrevista especial com Luiz Fernando Scheibe. Revista do Instituto Humanitas.  São Leopoldo, Unisinos, 13 de setembro de 2023.
Hubungan Komorbiditas dengan Mortalitas Pasien Diabetes Melitus di Ruang Intensive Care Unit (ICU)
Authors: Wirotomo Tri Sakti , Fijianto Dwi , Faradisi Firman , Pratiwi Yuni  Sandra
Published: June 2024

Diabetes melitus is a group of metabolic diseases characterized by hyperglicemia that occurs due to abnormalities in insulin secretion, insulin action or both. Diabetes melitus patients can experience a decline in health status which results in physiological changes that require treatment in an intensive care unit. Apart from causing complications, diabetes melitus also causes deterioration ogf the body’s system if the patien suffers from comorbidities. This study aim to determine the relationship between comorbidities and mortality in diabetes melitus patients treated in the intensive care unit. The research method is observational with a croos-sectional design. Sampling used total sampling. Data was obtained secondary data in form of medical records in the ICU room at Kajen Hospital, Pekalongan Regency in January-December 2022. The number of respondents was 40 diabetes melitus patients. Data analysis used the Pearson correlation statistical test to determine whether there are wasvrelationship between comorbidity and respondent mortality. The research results obtained a p-value of 0,022 (<0,05). The conclusion from this study is that there is a relationship between comorbidity and mortality of diabetes melituspatients in the intensive care unit of Kajen Regional Hospital, Pekalongan Regency.
Determinan Perilaku Ibu Hamil Dalam Melakukan Pemeriksaan Tripel Eliminasi
Authors: Kusumastuti Istiana , Istiani Hari Ghanesia
Published: June 2024

ABSTRACT
HIV, Syphilis and Hepatitis infections are infectious diseases that are still a health problem in the world, including in Indonesia. The incidence of transmission from mother to child ranks highest in the incidence of transmission in these 3 diseases. The purpose of this study was to determine the magnitude of the variable influence of information sources, the role of midwives, husband support, knowledge of maternal behavior in conducting triple elimination checks. This research method is Quantitative with cross sectional design with the analysis method used is SPSS. The sample of this study were all pregnant women with a total of 108. The results of the study using chi square on the variables of information sources, the role of midwives, husband support and knowledge have a significant influence on maternal behavior in conducting Triple Elimination checks where all variables have a p-value smaller than the provisions of 0.05. Based on the OR results of all variables, it can be seen that the information source variable has the greatest influence on maternal behavior in triple elimination checks in the Jabodetabek region, which is 4,870 times influential. It is recommended that education and information are continuously given to pregnant women.
Keywords: Behavior, Examination, Triple Elimination
Formulasi Antioksidan Minyak Daun Lemo (Litsea cubeba Pers.) Dengan Oleum Olivarum Sebagai Pelarut
Authors: Yulyana Ana , Satrio Ari Hutomo Satrio , Sholikha Munawarohthus
Published: June 2024

Litsea cubeba, also known as lemo, is a plant rich in antioxidant compounds and has been used in various studies to explore its potential in protecting the skin from oxidative damage. Recent research indicates that Litsea cubeba leaf oil possesses significant antioxidant activity, measured using the DPPH method, demonstrating its capacity to counteract free radicals. Additionally, this oil also contains vitamin E, known for its antioxidant properties, with measurable levels found in the studies. The physical stability of the lemo leaf oil formulation has also been evaluated, showing no change in shape or smell after a 14-day cycling test, indicating good potential for long-term application. These results affirm that Litsea cubeba holds great promise as a raw material in skincare products, particularly as an antioxidant, which can help protect the skin from the negative effects of free radicals and oxidation processes.
Hubungan Antara Kepatuhan Penggunaan Obat Dan Keberhasilan Terapi Pasien Diabetes Mellitus
Authors: Refdanita Refdanita , Musnelina Lili , Yulyana Ana , Hidayah Herawati Ratna , Miellana Nerry
Published: June 2024

Diabetes Mellitus merupakan penyakit kronis yang tidak dapat disembuhkan,sehingga terapi diberikan secara terus menerus dengan tepat. Salah satu penentu keberhasil terapi adalah kepatuhan penggunaan obat. Tujuan penelitian ini adalah untuk mengetahui hubungan antara kepatuhan penggunaan obat dan keberhasilan terapi pada pasien DM. Penelitian ini merupakan jenis penelitian ini adalah diskriptif analitik  dengan desain  cross sectional dan pengambilan data menggunakan metode prospektif. Penelitian ini dilakukan pada 235 pasien diabetes mellitus tipe 2 rawat jalan yang teratur kontrol dan mendapatkan antidiabetik oral pada terapinya. Responden ditetapkan dengan teknik purposive sampling. Hubungan skor kepatuhan dengan penurunan kadar gula darah puasa dianalisis menggunakan chi-square. Ditemukan pada penelitian ini bahwa penyakit DM lebih banyak diderita oleh laki-laki dengan usia  ≤ 65 tahun (57.4%).Terapi DM yang banyak diberikan adalah dalam bentuk kombinasi Metformin & Glimepiride (25,5%). Tingkat kepatuhan pasien berada pada tingkat tinggi (81,3%) dan tingkat rendah (18,7%).Dari analisis chi-square didapat nilai signifikasi 0.091> 0.05 maka, tidak terdapat hubungan bermakna antara kepatuhan penggunaan obat dengan keberhasilan terapi pada pasien DM
Isolation and Identification of Mycoflora in Mangroves Ecosystem in Mumbai Region
Authors: Mr. Udaybhan Yadav  , Mr. Kunal Thakur  , Sakshi Kumari Singh  , Rupali Radheshyam Yadav
Published: June 2024

Covering a quarter of the world’s tropical coastlines and being one of the most threatened ecosystems, mangroves are among the major sources of terrestrial organic matter to oceans and harbor a wide microbial diversity. In order to protect, restore, and better understand these ecosystems, researchers have extensively studied their microbiology, yet few surveys havefocused on their fungal communities. Our study indicates the presence of several species on this mycobiome that were not previously reported as mangrove-associated. In particular, we detected representatives of several commercially-used fungi, producers of secreted cellulases and anaerobic producers of cellulosomes. These results represent additional insights into the fungal community of the gray mangroves of the, and show that they are significantly richer than previously reported.
Effects of Petrol on Lab’s Bacteria and Fungus
Authors: Mr. Kunal Thakur  , Mr. Udaybhan Yadav  , Ms. Shrawni Rane
Published: June 2024

A variety of factors, including concentration of oil, antibiotics, dyes, and inoculum washes, were examined to determine their effect on the total counts of microorganisms on oil-containing media. Cleaning up of these pollutants from environment is a real-world problem. Bioremediation has become a major method employed in restoration of petroleum hydrocarbon polluted environments that makes use of natural microbial biodegradation activity. Petroleum hydrocarbons utilizing microorganisms are ubiquitously distributed in environment. They naturally biodegrade pollutants and thereby remove them from the environment. This article provides an overview about bioremediation for petroleum hydrocarbon pollutants. It also includes explanation about hydrocarbon metabolism in microorganisms.
Effect of Smoke on Normal Human Mouth Microflora
Authors: Kunal Thakur  , Udaybhan Yadav  , Lovlin Mandal
Published: June 2024

Cigarette smoking is a public health problem. It decreases the commensal population of normal flora in the oral cavity leading to an increase of pathogenic microbes. It causes oral cancer, periodontitis, colour change on the teeth, halitosis and other health implications. The study was designed to determine the changes caused by tobacco smoking on the microbial profile and oral health conditions of cigarette smokers. One hundred and twenty subjects comprising 60 tobacco smokers and 60 non smokers were enrolled for the study. Oral swabs were collected from the oral cavity of the subjects using sterile swab sticks under standard aseptic methods. The specimens were subjected to microscopy and culture. Organisms were identified using standard microbiological techniques. Higher rates of microbes 86.7% were recovered from the oral cavity of smokers than non smokers 33.3%.There was a statistically significant effect of tobacco smoke on the oral flora of smokers (χ2 = 299.0, P = 0.0002). Staphylococcus aureus 13(25.0%) and Klebsiella pneumoniae 10(19.2%) were more prevalent among smokers, while Klebsiella pneumoniae 4(20.0%) and Pseudomonas aeruginosa 4(20.0%) were the most prevalent bacterial isolates among the control subjects. Smokers had a diverse microbial colonization than non smokers. Smoking may have altered bacterial acquisition and oral mucosal colonization in favor of periodontal pathogens. The campaign against smoking should therefore be intensified as this may help to improve the oral health conditions of smokers. The oral microbiota has been observed to be influenced by cigarette smoking and linked to several human diseases. However, research on the effect of cigarette smoking on the oral microbiota has not been systematically conducted in the Chinese population.
Estimation of Antibacterial Properties in Attar Against Skin Microflora
Authors: Mr. Kunal Thakur  , Mr. Udaybhan Yadav  , Mr. Pratham Das
Published: June 2024

A flavorer inexperienced chance of perfumes is ‘attar’, that area unit non-alcoholic, oil-primarily primarily based completely, flavorer extracts derived from flowers, herbs, wood, etc. ottar may be an aromatic crucial oil; it's exhilarating and spiritually raising impact. ottar contains crucial oils that have a relaxing, soothing, and gratifying impact it is also recognized to supply comfort from headache. ottar in addition have healthful values, it will assist in comfort from respiratory illness, cough, and totally different respiratory issues. E. coli, enterobacteria pneumoniae, staphylococci aureus area unit the predominant organisms found on the skin. Skin microorganisms have essential roles within the protection against offensive pathogens, the education of our system and therefore the breakdown of natural merchandise. ottar might result the traditional flora of the skin attributable to the presence of lipide. The zone of inhibition may be a circular space round the spot of the antibiotic during which the microorganism colonies don't grow. A zone of inhibition, referred to as Kirby- Bauer technique take a look at may be a qualitative technique used clinically to live the resistance and industrially to check the flexibility of solids and textiles to inhibit microbic growth. By victimization this take a look at the consequences of ottar on traditional skin flora are often studied.
To Check the Toxicity of Plaster of Paris on Natural Water’s Microflora during Ganesh Chathurthi
Authors: Kunal Thakur  , Udaybhan Yadav  , Manisha Thakur
Published: June 2024

Ganpanti idol immersion each year during ganesh chathurthi is adding the load of pollution to the natural water bodies and the microflora of these water bodies too. Non biodegradable material and synthetic paint used in making these idols are causing serious threat to the microflora because of there chemical contents that may resist the growth of the bacteria. Present study was conducted to observe the effect of these idol made up of POP on water’s natural microflora. For this the water sample was collected after the immersion of ganpati idols. The water was taken from Sanjay Gandhi National Park (SGNP). The water had a great amount of calcium. There was a change in pH of water, hardness was seen in water taken after the immersion. Hydrological changes were observed in water due to ganpati idols immersion during and after the visarjan.
Study of Invitro Anti-Fungal Activity of Argemone mexicana against Fungi like Aspergillus niger and Candida albicans
Authors: Udaybhan Yadav  , Kunal Thakur  , Karina Jaiswal  , Lalit Rawat
Published: June 2024

Plants measure wealthy supply of medication for antifungal and antiviral properties. These properties are employed by plants to safeguard themselves from foreign particles or pathogens. With the advancement of techniques currently we tend to carry out extracting the chemicals and victimisation to cure plant and animal infection. The in vitro antifungal activity of binary compound extract from Argemone mexicana plants utilized in ancient drugs for the treatment of varied diseases. Extract effectivity was evaluated victimisation the agar well diffusion assay against two fungi i.e. Aspergillus niger and Candida albicans. Zone of inhibition against fungi was studied. The importance of those ends up in reference to ethnobotanical information which is mentioned.
Effects of Figs on Blood Glucose Level
Authors: Kunal Thakur  , Udaybhan Yadav  , Mimansha Tiwari
Published: June 2024

Figs have a high nutritional content and few calories. Abscisic acid (ABA), a naturally occurring hormone that controls the body's response to glucose and lowers inflammation, is abundant in figs. Researchers evaluated the extract's ability to reduce blood sugar levels in a glucose solution at different concentrations. This subject was chosen to investigate how figs affect blood sugar levels. In a sugar solution of 200 mg/mL distilled water, the enzymatic activity of figs was examined. The medical term for elevated blood sugar is hyperglycemia (blood sugar). It usually takes high blood sugar (glucose) levels, above 180 to 200 milligrams per deciliter (mg/dL), for hyperglycemia to manifest as symptoms. At 530 nm, the outcome was then spectrophotometrically verified. A steady decline in descending order was observed. As a result, figs' sugar-lowering activity was demonstrated..
Analisis Semiotika Representasi Nilai-nilai Islam Dalam Tayangan Film Ayat-Ayat Cinta
Authors: Riski Israq , Monang Sori , Batubara Abdul Karim
Published: June 2024

Film is one of mass media having responsibility to decrease and increase education like radio, television and newspapers as well. The form of religious values can be conveyed through messages in the film. This paper contains religious values in the film Ayat-Ayat Cinta. It uses semiotic analysis method by Pierce. Therefore, religious values that are delivered in the film Ayat-Ayat Cinta can be revealed. Firstly, the researcher chooses some scenes in the film Ayat-Ayat Cinta. Then, those scenes are analyzed through denotative, connotative, and myth meaning. Basically, there are many things which can be interpreted in a film. Of course, it must be suitable with the context rising in the scenes in order to result matters pertaining to meaning and understanding of messages. This is a qualitative research. It considers meaning as the main attention. In addition, this research only develops collecting facts. Thus, they are analyzed without doing hypothesis experiment. The researcher chooses the film Ayat-Ayat Cinta because there are many deviations happening today, especially for teenagers. It seems that Ayat-Ayat Cinta bringing freshness in order to give education and study about religious values. After a long process up to analysis, it results that Ayat-Ayat Cinta having religious messages which reveal in the scenes.