bluuebunny/crossref_metadata_2025 huggingface dataset:
Operasi Apik Untuk Gunung Cikuray Bersih, Sehat, Dan Lestari
Authors: Nurfadhilah Nurfadhilah , Komalasari Iis , Prabawa Agung
Published: November 2021

Mendaki gunung merupakan kegiatan olahraga sekaligus rekreasi yang dalam situasi tertentu mengakibatkan tumpukan sampah tertinggal di berbagai lokasi (puncak, sekitar kemah, dan sepanjang lintasan). Kegiatan bernama Operasi Bersih Sampah Gunung Cikuray bertujuan membersihkan lokasi terjangkau dari sampah, khususnya yang berbahan plastik. Kegiatan dilaksanakan pada Sabtu-Ahad, 29-30 Agustus 2020 melalui Kiara Janggot, Kota Garut, Jawa Barat. Kegiatan diikuti 52 orang dengan peserta termuda berusia 9 tahun dan tertua 45 tahun, 38 lelaki dan 14 perempuan. Sampah yang berhasil dikumpulkan dan dibawa ke kaki gunung berjumlah sekitar 60 kantong ukuran 3kg dan 15 karung ukuran 20 kg, total sekitar 400 kg. Jenis sampah umumnya botol  (botol plastik berisi urin, botol AMDK, botol minuman keras, tutup botol), pembalut, tisu, bungkus permen, bungkus mi instan, dan puntung rokok. Kegiatan ini sangat bermanfaat, selain bagi kebersihan, kesehatan, dan kelestarian lingkungan, juga bagi individu yang mengikuti kegiatan, baik secara fisik maupun mental.---Mountain climbing is a sport as well as recreational activity which in certain situations results in piles of garbage left in various locations (at the top, around the camp, and along the trails). The activity called Operation Mount Cikuray Garbage Cleanup aims to clean up affordable locations from rubbish, especially those made of plastic. The activity was carried out on Saturday-Sunday, 29-30 August 2020 through Kiara Janggot, Garut City, West Java. The activity was attended by 52 people with the youngest participants aged 9 years and the oldest 45 years, 38 men and 14 women. The garbage collected and brought to the foot of the mountain is around 60 and 15 20 kg sacks, a total of about 400 kg. Types of waste are generally bottles (plastic bottles containing urine, bottled drinking water bottles, liquor bottles, bottle caps), sanitary napkins, tissue wrappers, instant noodle wrappers, and cigarette butts. This activity is very beneficial, in addition to cleanliness, health and environmental sustainability, as well as for individuals who participate in the activity, both physically and mentally.
Mitologizmy frazeologiczne w najnowszych ujęciach lingwistycznych
Authors:   Uniwersytet Pedagogiczny w Krakowie, Puda-Blokesz Magdalena
Published: November 2021

Mythology-based phraseological expressions in the latest linguistic approaches Summary The present study represents an overview and a synthesis of the latest linguistic findings regarding phraseology with provenance in (Greco-Roman) mythology. The text refers to the most recent works, mostly published after 2000, which explore – solely or largely – mythology-based phraseological expressions. The issue of defining this term is discussed, its content and the breadth of its meaning are delineated, various classification and description criteria for such expressions are pointed out. The research standpoints put forward in the studies discussed may be described as having a comparative, etymological, statistical-theoretical, didactic, discursive-material or lexicographic inclination. By virtue of the subject matter along with its cultural and identity-related importance, the common denominator of the viewpoints presented is the domain of cultural linguistics.
Przyimki i polityka
Authors:   Uniwersytet Jagielloński, Przybylska Renata
Published: November 2021

Prepositions and Politics Summary The author argues with S. Westfal’s thesis (1936) that the use of expressions na Litwie, na Litwę instead of w Litwie, do Litwy is an expression of intellectual superiority. She presents the results of a corpus- based analysis of these expressions and makes recommendations, how they should be used nowadays due to the political correctness.
Gwarowy szkut ‘chłopak’ w polszczyźnie potocznej
Authors:   Instytut Języka Polskiego PAN w Warszawie, Kucharzyk Renata
Published: November 2021

The dialectal word szkut ‘boy’ in colloquial Polish Summary The subject of the article is the occurrence of dialectism ‘male child; boy’ in colloquial Polish. This word – despite its dialectal origin – is present in the statements of not only the users of the local dialect, but also of people who do not speak the dialect. The example material was excerpted mainly from the statements of Internet users posted on Internet forums. It seems that the lexeme is slowly stabilizing in colloquial language to the extent limited to one region – south-eastern Lower Poland, and is becoming another micro-regionalism.
Dyskurs handlowy Krakowa z końca XIX i początku XX wieku jako źródło do badań regionalizmów krakowskich
Authors:   Uniwersytet Jagielloński, Kwaśnicka-Janowicz Agata , Pałka Agnieszka ,   Uniwersytet Jagielloński
Published: November 2021

Cracow’s commercial discourse from the end of the 19th and beginning of the 20th century as a source of research on Cracow regionalisms Summary The aim of the article is to analyze the selected texts representing a commercial discourse used in Cracow at the turn of the 19th and 20th centuries. These texts are primarily the price lists of goods, kept in the resources of the Jagiellonian Library, the Museum of Cracow and the National Museum in Cracow. In the analysis of the collected materials, the Authors limit themselves to describing the regionally diverse culinary lexis (from the thematic field of sweets and desserts). They describe the lexical units that have been confirmed in the research as Cracow regionalisms (e.g. andruty ‘andruts’, makaroniki ‘macaroons’, precle ‘pretzels’). In addition, the authors verify the hypothesis about the regional character of the lexeme pomadka ‘soft candy / chocolate’.
Przydatność Wielkopolskich Słowników Regionalnych do badania fleksji gwarowej rzeczownika
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Kobus Justyna
Published: November 2021

Usefulness of Greater Poland Regional Dictionaries for the study of dialectal inflection of a noun Summary In the article are presented Greater Poland Region Dictionaries as a source of grammatical material, mainly concerning the noun. The author present the advantages and disadvantages of this type of materials as a basis for systemic research on the language of rural residents. From these dictionaries there are cited authentic examples.
Miłośnictwo polszczyzny dzisiaj z perspektywy komunikacyjnej, aksjologicznej i edukacyjnej
Authors:   Państwowa Wyższa Szkoła Zawodowa w Tarnowie, Kowalikowa Jadwiga , Choińska Krystyna ,   Państwowa Wyższa Szkoła Zawodowa w Tarnowie
Published: November 2021

Passion for the Polish language from the communicative,axiological and educational perspectives Summary The article explores the passion for the Polish language in contemporary society, taking into account its source, history, as well as various options for its dissemination through opularization. The study is conducted from the linguistic, communicative, axiological and communicative perspectives.
Słownictwo z pola tematycznego kuchnia i sprzęty kuchenne w gwarze polskiej w obwodzie lwowskim
Authors:   Instytut Języka Polskiego PAN w Krakowie, Kostecka-Sadowa Anna
Published: November 2021

Vocabulary from the subject field kitchen and kitchen utensils in the Polish dialect in the Lviv region Summary The aim of article is to show the dynamics of changes in the functioning of borrowings from Ukrainian (and Russian) language. The collected and evoked lexis concerns the thematic field related to the names of kitchen in the Polish dialect of the village of Czyszki. The lexeme borrowed will be ilustrated with contexts and information about the informant’s generational affiliation. The generational order will allow to illustrate the lifetime of specific names in particular generational compartments. This method will also make it possible to observe the groups of vocabulary coming out of use as well as those that are being actively used by all informants all the time.
Język a tradycja narodowa. Stosunek Polaków do języka na podstawie wybranych komentarzy w dyskusji poprzedzającej Narodowe Czytanie 2018
Authors:   Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Garnek Małgorzata
Published: November 2021

Language and national tradition. Relationship between Poles and their language based on selection of comments on discussion preceding National Reading Day 2018 Summary The main issue of the article refers to the relationship between Poles, their mother tongue and literary tradition, which appeared in the vivid discussion preceding The National Reading Day of 2018. For this purpose, Author has presented the controversy caused by the adaptation of Przedwiośnie by Stefan Żeromski made by Andrzej Dobosz. Author has selected and analyzed opinions and comments of Internet users and cartoonists posted on websites such as serwis.gazetaprawna.pl, wyborcza.pl, wiadomości.wp.pl. With usage of the method of precise semantic-lexical description, Author has captured various shades of meaning, assigned to words in the analyzed statements.
Grzeczność i agresja językowa w komentarzach internautów
Authors:   Państwowa Wyższa Szkoła Zawodowa w Tarnowie, Pachowicz Małgorzata
Published: November 2021

Politeness and linguistic aggression in internet users’ comments Summary The presented considerations concern various forms of polite and aggressive linguistic behavior that collide in the comments of Internet users. Politeness manifests itself in various forms, following the patterns of traditional linguistic etiquette or modified by Internet users. Aggression is a form of verbal attack in which all linguistic means are used to discredit a given person. Both of these linguistic behaviors, especially in Internet comments,will change their faces and therefore it is worth observing and analyzing them.
Co z tym Niemaszem, czyli fraza nie masz w funkcji egzystencjalnej jako problem transkrypcji tekstów staropolskich Słowa
Authors:   Instytut Języka Polskiego PAN w Krakowie, Duska Joanna
Published: November 2021

Niemasz that is the phrase nie masz in the existential function as a problem of Old Polish text transcription Summary The present author while working on the final edition of Jan Kochanowski’s Dzieła wszystkie became interested in the problem of Old Polish transcription of the phrase nie masz and in its placement in word indexes. On the basis of Polish lexicons, dictionaries of Old Polish and Old Polish texts the author contrary to some editors’ practice who write niemasz or nie ma-ż concludes that the spelling nie masz is justified. Following the semantics of the quoted forms she shows that they are synonymous and follows a history of their occurrence in Polish. She also claims that despite the fact that in both forms the present tense expresses timelessness and they are generalized in the 2nd and 3rd person singular, formally they are predicates and they should be treated as other verbs in indexes.
Zaczątki sylwetki w prasie. Uwagi historyka języka
Authors:   Uniwersytet Łódzki, Pietrzak Magdalena
Published: November 2021

The beginnings of the profile in the press. Comments of a language historian Summary The author of the analysis tries to establish the beginnings of a press profile and indicate its main specific features. The basis for the analysis are the press articles published in the Warsaw press. The research showed that the first articles that were to present a person and her or his achievements appeared in the context of death notifications. Those were the profiles of well-known people (representatives of the church hierarchy, high-ranking civil servants, members of noble families). A death notification consisted of several parts: an information about the death of a certain person (time, place, circumstances of death, age), a presentation of this person and her or his achievements (forms of occupation, position, merits, advantages of character; religious practices – especially in reference to women), an information about the funeral mass. That type of a press article shows a significant affinity with other funeral forms, that is with the memorial note and obituary, and can be (from the diachronic perspective) classified to those genres.
Sylwetka odbiorcy w przedmowach z okresu II poł. XVII i I poł. XVIII wieku w ujęciu chronologicznym
Authors:   Instytut Języka Polskiego PAN w Warszawie, Rodek Ewa
Published: November 2021

Receiver profile in prefaces from the 2nd half of 17th and 1st half XVIII century in chronological terms Summary The article presents an outline of the intended recipient of works from mature and late Baroque on the basis of research on 160 preface to works published in the years 1650–1750. The chronological order of the sources makes it possible to compare how the recipient’s attributes have changed over the course of this century. The characteristics of readers are associated with several thematic circles. In some periods, the intended recipient is very schematic, which results from the high degree of formality of the preface genre.
Integracja Elektronicznego słownika języka polskiego XVII i XVIII wieku i Elektronicznego Korpusu Tekstów Polskich z XVII i XVIII Wieku okiem użytkownika i redaktora
Authors:   Instytut Języka Polskiego PAN w Krakowie, Wieczorek Aleksandra
Published: November 2021

Integration of the Electronic Dictionary of the 17th- and 18th-century Polish and the Electronic Corpus of 17th- and 18th-century Polish Texts from the viewpoint of the user and the editor Summary The article presents the recently carried out improvements in navigating between two electronic resources: the Electronic Dictionary of the 17th- and 18th-century Polish and the Electronic Corpus of 17th- and 18th-century Polish Texts. These important changes are intended both for the users of the two resources as well as for the editors of the dictionary. For users’ convenience, there are links in each dictionary entry that allow for finding additional examples of the usage of a given lexeme. Moreover, on the corpus website below the search results there is a shortened version of the appropriate dictionary entry and a link to its full entry. The functions for downloading data from the corpus for the use of the dictionary have also been created, which significantly facilitates dictionary editors’ work.
Obraz postawy człowieka wobec sacrum w tekstach piosenek (na przykładzie tekstów wykonywanych przez polskojęzyczne dzieci parafii Boskiego Serca Pana w Czeskim Cieszynie)
Authors:   Uniwersytet Ostrawski, Kolberová Urszula
Published: November 2021

The picture of the human attitude towards the sacred in the songs (on the example of texts performed by polish-speaking children from Divine Heart Parish in Czech Cieszyn) Summary The subject of this article are texts of songs performed by children and young people in the Czech-Cieszyn Divine Heart Parish, or more precisely, the emerging image of the attitude that a person should adopt towards the sacred, his place in relation to holiness. The analysis of the texts showed that the texts most often evoke the inferiority, obedience and servility of man, then thanksgiving, gratitude for life and salvation, praise of God, especially through singing. Man should adore God, love, trust in him, hope in him and strive for the sacred. Man desires closeness to the sacred, he needs a Lord through whom he satisfies his needs. After all, he should also spread he faith.
O zastosowaniu teoretycznych badań konfrontatywnych z językiem pośrednikiem w badaniach polonistycznych
Authors:   Uniwersytet Warszawski, Roszko Danuta , Roszko Roman ,   Uniwersytet Warszawski
Published: November 2021

The application of theoretical contrastive analysis using an interlanguage in Polish studies Summary The article presents the methodology of theoretical contrastive analysis using an interlanguage. A parallel contrastive description is facilitated by a semantic interlanguage, which is created prior to work on the linguistic material. The article, based on the example of selected semantic meanings (units) in the category of definiteness / indefiniteness, proves the added value in Polish, which arises simultaneously from the application of theoretical contrastive analysis using an interlanguage and the exploration of the resources of the Polish-Lithuanian Parallel Corpus. The authors perform a projection of clear characteristics of Lithuanian onto Polish, thereby enriching and more precisely defining the description of exponents of the definiteness/indefiniteness semantic category in the Polish language.
Jubileusz, rocznica a może urodziny? – leksykograficzne dywagacje na kanwie stulecia Towarzystwa Miłośników Języka Polskiego
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Migdał Jolanta , Piotrowska-Wojaczyk Agnieszka ,   Uniwersytet im. Adama Mickiewicza w Poznaniu
Published: November 2021

Jubilee, Anniversary or Maybe Birthday? – Lexicographic Examination Inspired by One Hundred Years of The Society of Friends of the Polish Language Summary One hundred years of the Society of Friends of the Polish Language became an inspiration for us to present a lexicographic history of words referring to this highly regarded event. The following lexemes have been examined: jubilee, anniversary and birthday. The analyses, carried out on the basis of their dictionary entries, indicate a number of different transformations on the semantic level.
El consumo de la muerte en las televisiones nacionales: necroliberalismo y la nación cyborg en Ruido Gris de Pepe Rojo
Authors: Dalton David
Published: November 2021

El presente estudio indaga sobre la confluencia del neoliberalismo y el avance tecnológico en el México de los noventa a través del cuento Ruido gris (1996) de Pepe Rojo. El cuento narra la vida de un personaje sin nombre que se ha convertido en un “reportero ocular” después de instalarse una cámara en el ojo derecho mediante una operación. Este personaje fomenta un diálogo fructífero entre la teoría cyborg ‒que ha visto la hibridez tecnológica como un estado libertador‒ y la biopolítica, en un contexto neoliberal donde las grandes empresas sacan provecho de la muerte y del sufrimiento humanos. Interpretamos al narrador como un actor robo sacer, ya que su condición cyborg contribuye a su marginación y al mismo tiempo conforma sus vías de resistencia. Así que este cuento nos permite cuestionar hasta qué punto la resistencia cibernética puede ser útil en una sociedad cuya única lógica es el lucro. El cuento reconoce ciertas avenidas para una resistencia cibernética limitada, pero duda de su potencial de cambiar las estructuras económicas y biopolíticas que rigen en la sociedad, ya que la mayoría de los intentos de resistir terminan validando el orden necroliberal.
Territorios de la crítica: imaginación, género y violencia en la literatura hispanoamericana
Authors: Rivera Guevara María Elena
Published: November 2021

Leticia Mora Perdomo. (2020). Territorios de la crítica: imaginación, género y violencia en la literatura hispanoamericana, pp. 266. ISBN 9786075028798. Xalapa: Universidad Veracruzana/El Colegio de San Luis.¿De qué hablamos cuando hablamos de literatura hispanoamericana? ¿Es esta categoría lo suficientemente nítida para abarcar temas, géneros y autores de naturaleza heterogénea? ¿Cuáles son las tendencias actuales de la crítica al respecto? Estas y otras inquietudes son mencionadas en el presente libro, el cual reúne 12 ensayos, cuya autoría corresponde a investigadores de diferentes universidades de México.
La iniciación literaria de Gabriel García Márquez
Authors: Rama Ángel
Published: November 2021

La iniciación literaria de Gabriel García Márquez indaga en la cuentística inicial del escritor colombiano, publicada entre 1947 y 1954, mientras vivía entre Cartagena y Barranquilla. El artículo se propone revisar los orígenes del escritor, donde consuma el hallazgo de una temática, un orbe cultural específico y una militancia estética. También se trata de visitar las fuentes naturales y sociales de la cosmovisión del colombiano, de su universo lírico y onírico, alimentado con las tradiciones locales y populares, aunadas a las propuestas narrativas inglesas y norteamericanas de ese periodo. Finalmente, se dialoga con una treintena de cuentos –recogidos después, en su mayoría, en Ojos de perro azul– escritos, en esos años juveniles, con formas tradicionales y con formas novedosas, signadas por el espíritu de búsqueda y por un progresivo ajuste de la expresión literaria, cuya concreción primera se dará, posteriormente, en algunos de los cuentos de Los funerales de la Mamá Grande –“La siesta del martes”, “En este pueblo no hay ladrones”– y en esa obra maestra de la novela corta que es El coronel no tiene quien le escriba.Gabriel García Márquez’s literary initiationAbstractGabriel García Márquez’s literary initiation researches the Colombian first short stories, published between 1947 and 1954, while he was living between Cartagena and Barranquilla. This essay covers the writer’s origins, wherethe discovery of a theme, as well an specific cultural sphere with and aesthetic militancy is consummated. It also tries to visit the natural and social sources of the Colombian worldview, of his lyrical and dream universe, fed with local and popular traditions, and put together with the english and northamerican narratives of that period. Finally, it tries to create a dialogue between thirty short stories –which were recollected later, most part in Ojos de perro azul–, written in those youthful years, with traditional forms and new forms, marked by the spirit of search and by a progressive adjustment of the literary expression, whose first effects will be shown in some short stories from Los funerales de la Mamá Grande –“La siesta del martes”, “En este pueblo no hay ladrones”– and in that masterpiece of the short novel that is El coronel no tiene quien le escriba.
Los hijos de Pedro Páramo
Authors: Ruffinelli Jorge
Published: November 2021

Dos ideas guían el análisis de Pedro Páramo en este artículo: qué motivos profundos explican la liga entre los medio hermanos Juan Preciado, Miguel Páramo, Abundio Martínez y Pedro Páramo, el padre, y cuál es la consecuencia final de esa liga. Desde la textualidad, se propone tres lecturas: 1) Preciado busca al padre porque a través de él podría lograr una plena identificación con Dolores Preciado y sus vivencias; es una búsqueda que concluye en fracaso: no encontrará al padre y, por tanto, tampoco a su madre. 2) Miguel se identifica con Pedro Páramo, pero desafía su autoridad y muere cuando aspira a afirmar su marca identitaria, es decir, como su hermano Juan, también él fracasa en la concreción de sus deseos. 3) Abundio “cumple con el mandato original y ejecuta el ‘castigo’ sobre el padre”, esto es, cobra con sangre la orfandad, la negación de identidad y el abandono de los hijos. Tales lecturas se unen a otras, psicoanalíticas o míticas, ofreciendo así una diversidad interpretativa de la novela.Pedro Páramo’s childrenAbstractTwo ideas guide the analysis of Pedro Páramo: what profound motives explain the link between the half brothers Juan Preciado, Miguel Páramo, Abundio Martínez and Pedro Páramo, the father, and what is the final consequence of this link. After the textual aproach, proposis three readings: 1) Preciado looks for his father because through him he could achieve a full identification with Dolores Preciado and her most revitalizing and dreamy experiences; it becomes a search that ends in failure because he will never find his father, no matter how much he looks for him, and therefore, neither will his mother. 2) Miguel identifies fully with Pedro Páramo but challenges his authority and passes away when he aspires to affirm his identity, that is, as his brother Juan, he too fails in trying to make his most deep and intense desires. 3) Abundio “complies with the original command and executes the ‘punishment’ on the father”, that is, he charges with blood, the orphanhood, the denial of identity and the abandonment of the children. These readings are joined with others, like psychoanalytic or mythical, thus offering an interpretative diversity of the novel.
СВОТ-АНАЛІЗ ЯК ІНСТРУМЕНТ УПРАВЛІННЯ МІЖНАРОДНОЮ КООПЕРАЦІЄЮ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ
Authors: Bebko Svitlana
Published: November 2021

У статті розглянуто основні поняття, пов’язані з кооперацією, а також особливості міжнародної кооперації закладів вищої освіти. За допомогою інструментарію стратегічного управління, зокрема СВОТ-аналізу, виявлено основні переваги та проблеми міжнародної кооперації закладів вищої освіти України, визначено можливості й за-грози, що створює для неї зовнішнє середовище, вплив об’єктивних факторів, якого важко або неможливо уникнути, проте необхідно реагувати. Доведено, що використання СВОТ-аналізу як інструменту управління міжнародною кооперацією університетської освіти дає можливість не лише оцінити її сильні і слабкі сторони, можливості й загрози, але скористатися одержаною інформацією для побудови стратегії її подальшого розвитку в умовах мінливого глобалізованого світу, жорсткої конкуренції з боку потужної системи вищої освіти розвинених країн Європи та світу і, як результат, забезпечити ефективну реалізацію місії вітчизняної вищої школи.
Biochemical and genetic characterization of 16 patients with propionic acidemia
Authors: Галушкин А.С. , Пыркова Е.Ю. , Куркина М.В. , Михайлова С.В. , Воронцова В.П. , Грибов Д.И. , Заживихина М.В. , Слатецкая А.Н. , Какаулина В.С. , Печатникова Н.Л. , Полякова Н.А. , Варга Н.Д. , Жукова Е.Г. , Байдакова Г.В. , Бычков И.О. , Баранова П.В. , Иткис Ю.С. , Ларшина Е.А. , Крылова Т.Д. , Захарова Е.Ю.
Published: November 2021

Пропионовая ацидемия (ПА) - редкое наследственное заболевание с аутосомно-рецессивным типом наследования, относится к «классическим», т.е. наиболее часто диагностируемым органическим ацидемиям. В данной работе представлена биохимическая и молекулярно-генетическая характеристика 16 пациентов с ПА, выявленных в Российской Федерации. У большинства обследованных пациентов первые симптомы проявились в первые месяцы жизни, наиболее частые из них: нарушения вскармливания, судороги, мышечная гипотония, угнетение сознания. При биохимическом исследовании (ГХ-МС и МС/МС) у пациентов было выявлено повышение концентрации 3-гидроксипропионой кислоты, метилцитрата, пропионилглицина, C3, глицина, которые являются патогномоничными маркерами этой патологии. В результате молекулярно-генетического анализа в генах PCCA и PCCB было выявлено 6 неописанных ранее вариантов нуклеотидной последовательности (4 варианта в гене PCCA, 2 - в гене PCCB), один из которых (PCCB: c.655-2A>G) имеет высокую частоту (17,2%, 5/29 мутантных аллелей генов PCCA и PCCB) в исследуемой выборке. Локализация миссенс-вариантов и их влияние на структуру белка были продемонстрированы на 3D-модели фермента пропионил-КоА-карбоксилазы. Выявленным вариантам были присвоены критерии патогенности в соответствии с рекомендациями American College of Medical Genetics and Genomics (ACMG).

Propionic acidemia is a rare autosomal recessive metabolic disorder, characterized as classic organic acidemia. The article represents biochemical and molecular characterization of 16 patients diagnosed with propionic acidemia in Russia. Symptoms appeared during the first months after birth in most cases. Poor feeding, seizures, hypotonia, lethargy were the most frequent symptoms. Biochemical tests (GC-MS and MS/MS) showed elevated 3-hydroxypropionic acid, methylcitrate, propionylglycine, C3 in patients blood. Six undescribed earlier variants were found as a result of PCCA & PCCB (4 variants - PCCA, 2 - PCCB) genes DNA-tests. Variant c.655-2A>G in PCCB is the most frequent in this group (17.2%). Localization of missense variants and their effect on protein was demonstrated using propionyl-CoA carboxylase 3D model. New variants were classified according to the American College of Medical Genetics and Genomics (ACMG) guidelines.
Multiscale modeling of bio-nano interactions of zero-valent silver nanoparticles.
Authors: Subbotina Julia , Lobaskin Vladimir
Published: November 2021

Understanding the specifics of interaction between protein and nanomaterial is crucial for designing efficient, safe, and selective nanoplatforms, such as biosensor or nanocarrier systems. Routing experimental screening for the most suitable complementary pair of biomolecule and nanomaterial used in such nanoplatforms might be a resource-intensive task. While a variety of computational tools is available for pre-screening libraries of small drug molecules interacting with proteins, options for high-throughput screening of protein libraries for binding affinities to new and existing nanomaterials are limited. In the current work, we present the results of a systematic computational study of protein interaction with zero-valent silver nanoparticles using a multiscale approach. A variety of blood plasma and dietary proteins, namely, bovine and human serum albumins, bovine and human hemoglobin, papain, bromelain, lysozyme, and bovine lactoferrin, were examined. Selected combinations of nanomaterial and proteins can serve as a starting model for developing noble metal-based nanocarriers and biosensors. The computed binding (adsorption) characteristics for selected proteins were validated by experimental data reported in the literature. An advanced in silico nano-QSAR/QSPR interfacial descriptor 〖log⁡P〗^NM was also introduced to characterize the relative hydrophobicity/hydrophilicity of the nanomaterial.
Global analysis of crystal energy landscapes: applying the threshold algorithm to molecular crystal structures
Authors: Yang Shiyue , Day Graeme
Published: November 2021

We describe the implementation of the Monte Carlo threshold algorithm for molecular crystals as a method to provide an estimate of the energy barriers separating crystal structures. By sampling the local energy minima accessible from multiple starting structures, the simulations yield a global picture of the crystal energy landscapes. This provides valuable information on the depth of the energy minima associated with crystal structures and adds to the information available from crystal structure prediction methods that are used for anticipating polymorphism. We present results from applying the threshold algorithm to four polymorphic organic molecular crystals, examine the influence of applying space group symmetry constraints during the simulations, and discuss the relationship between the structure of the energy landscape and the intermolecular interactions present in the crystals.
Direct Synthesis of Vinylene Carbonates from Aromatic Aldehydes
Authors: Onida Killian , Ibrahimli Leyli , Duguet Nicolas
Published: November 2021

Substituted vinylene carbonates were directly prepared from aromatic aldehydes following a one-pot Benzoin condensation / transcarbonation sequence under solvent-free conditions. The combination of a N-phenyl substituted triazolium salt NHC precursor and 4-dimethylaminopyridine (DMAP) was found essential to reach high yield and selectivity. The reaction scope was investigated with a range of aromatic aldehydes and the corresponding vinylene carbonates were obtained with 32-86% isolated yields (14 examples).
Co@CoO: a Unique Catalyst for Hydrogenolysis of Biomass-derived 5-Hydroxymethylfurfural to 2,5-Dimethylfuran
Authors: Xiang Shuang , Dong Lin , Wang Zhiqiang , Han Xue , Daemen Luke , Cheng Yongqiang , Guo Yong , Liu Xiaohui , Ramirez-Cuesta Anibal J , Yang Sihai , Gong Xue-Qing , Wang Yanqin
Published: November 2021

The development of precious-metal-free catalysts to promote the sustainable production of fuels and chemicals from biomass remains an important and challenging target. Here, we report the efficient hydrogenolysis of biomass-derived 5-hydroxymethylfurfural to 2,5-dimethylfuran over a unique core-shell structured catalyst Co@CoO that affords the highest productivity among all catalysts reported to date. Surprisingly, we found that the catalytically active sites reside on the shell of CoO with oxygen vacancies rather than the metallic Co. The combination of various spectroscopic experiments and computational modelling reveals that the CoO shell incorporating oxygen vacancies drives the heterolytic and homolytic cleavage of dihydrogen to yield active Hδ- species, resulting in the exceptional catalytic activity. Co@CoO also exhibits excellent activity toward the direct hydrodeoxygenation of lignin model compounds. This study unlocks, for the first time, the potential of metal-oxide catalysts for the production of renewable biomass-derived fuels.
Radical Perfluoroalkylation Enabled by a Catalytically Generated Halogen Bonding Complex and Visible Light Irradiation
Authors: Tasnim Tarannum , Ryan Calvin , Christensen Miranda , Fennell Christopher , Pitre Spencer
Published: November 2021

Despite the many recent advances in exploiting stoichiometric charge-transfer complexes in visible light promoted single-electron redox reactions, catalytic approaches to charge-transfer complex formation remain limited. This report describes the radical perfluoroalkylation of electron-rich (hetero)arenes and iodoperfluoroalkylation of alkenes and alkynes promoted by a substituted hydroquinone catalyst. Mechanistic and computational studies indicate that the reaction is initiated by the formation of a visible light absorbing halogen bonding complex between the hydroquinone catalyst and the perfluoroalkyl iodide radical precursor.
Infrastructures of Play: Labor, Materiality, and Videogame Education
Authors: Watson Jeff
Published: November 2021

Preparing students for the job market is not the limit of our responsibilities as videogame educators. We must also prepare them to be ethical actors within the industries they may join. This paper argues for augmenting player-centric videogame design education and game studies pedagogies with approaches that situate videogames in context as operational components of extractivist business models and the political and financial economies that support them. This approach entails teaching videogames as technical systems with complex and expansive upstream and downstream supports and impacts. These supports and impacts have real and frequently detrimental effects on the environment, communities, and individual human lives, and yet are relatively rarely discussed in the literature, especially in comparison to discussions that focus on representation and rhetoric. By looking beyond the frame of the individual videogame as an expressive artifact, educators can help learners to apprehend issues such as the growing material and environmental costs of computer-based entertainment and the many tiers of labor exploitation involved in producing videogames and the computing machinery that makes them possible, among other concerns. The paper concludes by suggesting that students equipped with these kinds of understandings will be able to make more informed ethical assessments, and thus wiser choices, as they percolate into the videogames industries and, in some cases, into positions of leadership.
Показатели иммунитета, тревожность и соматическая патология как факторы формирования затяжного течения панического расстройства
Authors: Никитина В.Б. , Казенных Т.В. , Белокрылова М.Ф. , Рудницкий В.А. , Гарганеева Н.П. , Бохан Н.А.
Published: November 2021

Паническое расстройство – одно из наиболее распространенных непсихотических психических расстройств, в его клинической картине ведущее значение имеют периодическое возникновение приступов панических атак различной интенсивности, страх и тревога ожидания новых приступов с различными вегетативными симптомами и высокая вероятность формирования ограничительного поведения. При отсутствии своевременного лечения паническое расстройство приобретает затяжное течение, что приводит к социальной дезадаптации. Цель. Выделить иммунологические и клинико-психологические предикторы затяжного течения панического расстройства. Материал и методы. Проведено комплексное клинико-психопатологическое, психологическое и иммунологическое обследование 48 пациентов с паническим расстройством (по МКБ-10 F41.0). По течению и длительности заболевания были сформированы две клинические группы: 1-я группа (23 чел.) – умеренное течение панического расстройства с длительностью заболевания менее 3 лет; 2-я группа (25 чел.) – затяжное течение панического расстройства с длительностью заболевания более 3 лет. Все пациенты прошли обследование у терапевта на предмет выявления соматической патологии. Оценивали уровень личностной и реактивной тревожности. Лабораторное исследование включало фенотипирование иммунокомпетентных клеток по кластерам дифференцировки методом проточной цитометрии. Все данные были статистически обработаны. Результаты. На основе клинико-иммунологического подхода разработан способ прогнозирования затяжного течения панического расстройства. При наличии у пациентов с умеренным течением панического расстройства соматических заболеваний, уровня личностной тревожности более 53 баллов и содержании в крови активированных Т-лимфоцитов (CD3+HLA-DR+) более 13% прогнозируют затяжное течение панического расстройства с длительностью заболевания более 3 лет. Заключение. Предложенный способ может быть широко использован в медицине и здравоохранении для прогноза затяжного течения панического расстройства, что позволит оптимизировать психотерапевтические и фармакологические мероприятия.
Стресс, тревога и депрессия у медицинских работников, оказывающих помощь пациентам с COVID-19 в Республике Бурятия
Authors: Лубсанова С.В. , Гриф В.Л. , Сымбелова Т.А. , Убеева Е.А.
Published: November 2021

Актуальность. При пандемии COVID-19 медицинские работники испытывают профессиональные риски, так как осуществляют трудовую деятельность в условиях повышенной нагрузки с беспрецедентным количеством тяжелобольных пациентов, часто непредсказуемым течением болезни, высокими показателями смертности, необходимостью ношения средств индивидуальной защиты и связанными с этим физиологическим дискомфортом, потребностью повышения квалификации в области диагностики и терапии новой коронавирусной инфекции, стигматизацией и страхом заражения себя и близких, что вызывает проблемы психического здоровья ‒ стрессовые, тревожные и депрессивные расстройства. Цель исследования: оценка проявлений стресса, тревоги и депрессии у медицинских работников, оказывающих помощь пациентам с COVID-19 в Республике Бурятия. Материалы и методы. В анонимном невыборочном опросе приняли участие 108 медицинских работников (48 врачей, 39 медсестер/медбратьев, 21 младший медицинский работник), оказывающих помощь пациентам с COVID-19 в Республике Бурятия. Симптомы стресса и тревоги оценивались по русской версии шкалы Стресс и тревога во время вирусной эпидемии – 9-пунктный опросник (SAVE-9) для медицинского персонала, тревожные и депрессивные проявления ‒ по Госпитальной шкале тревоги и депрессии (HADS). Результаты. По данным шкалы SAVE-9 респонденты часто или постоянно беспокоились, что члены семьи или друзья заразятся от них (30,6%), что могут заразиться сами (25,9%), что у коллег будет больше работы из-за их отсутствия на работе вследствие возможного карантина, что коллеги могут обвинить их из-за повышенной рабочей нагрузки (20,4%). Среди опрошенных медицинских работников отмечен высокий уровень тревожных (36,1%) и депрессивных (38,9%) симптомов по шкале HADS. Заключение. Для индивидуализации лечебно-реабилитационных и профилактических мер медицинским работникам, оказывающим помощь пациентам с COVID-19 в Республике Бурятия, необходимо уточнение роли в возникновении стрессовой, тревожной и депрессивной симптоматики таких показателей, как пол, возраст, национальность, должность, наличие перенесенной новой коронавирусной инфекции.
Clasificador de objetos en MATLAB® con redes neuronales de aprendizaje profundo
Authors: Guzmán Lembo Allison , Mayorga Alvarado Carlos Daniel , Dávila Vázquez Jimena Fernanda , Martínez Reyna Jonathan , Rodriguez-Liñan Angel , Torres-Treviño Luis M.
Published: November 2021

En este trabajo, de manera introductoria se ilustra la implementación de tres redes neuronales preentrenadas con el paradigma de aprendizaje profundo en el software MATLAB®, que pueden reconocer objetos en imágenes capturadas por una cámara. Mediante experimentos para reconocer objetos, se determinó cuál de estas redes tuvo mejor desempeño, aprovechando una base de datos estándar de imágenes. Dichos resultados se ilustran con ejemplos del uso del software y con datos comparativos de los aciertos.
Aşk-ı Memnu ve Anna Karenina Romanlarında Üçgen Arzu
Authors: ADIGÖZALOVA Aysel
Published: November 2021

Türk ve Rus edebiyatlarının üstatları Halit Ziya Uşaklıgil ve Lev Tolstoy günümüze kadar aktüelliğini kaybetmemiş eserler kaleme alan yazarlardır. Farklı kültürel dünyalara mensup olan bu iki yazarın kesişme noktası Anna Karenina ve Aşk-ı Memnû romanlarıdır. Halit Ziya Uşaklıgil ve Lev Tolstoy kırık hayat ressamlarıdır. Eserlerinde yargılamadan çekinen; tarafsız kalmayı tercih eden yazarlardır. İncelediğimiz romanlar farklı dönemlerde, farklı toplumsal şartlar altında yazılmış olsa bile aşk temelli üçgen ilişkiyi ele almanın yanı sıra servetin sevgi ihtiyacını karşılayabileğini düşünen, içsel savaşa yenik düşmüş ve sonunda bilinçsizce intihar eden trajik kadınlardan bahseder. Bu çalışmanın amacı Lev Tolstoy ve Halit Ziya Uşaklıgil’in Anna Karenina ve Aşk-ı Memnû romanlarında tasvir edilen çetrefilli ilişkiyi Renê Girard’ın Romantik Yalan ve Romansal Hakikat kitabında geliştirdiği üçgen arzu teorisi ile incelemektir.
El delito de estafa en el Código Orgánico Integral Penal. Breve análisis del tipo penal y las reformas del 2019.
Authors: Farto Crespo Hernán
Published: November 2021

La evolución del tipo penal de estafa en el Ecuador es un reflejo de la necesidades de protección ante el avance de la sociedad en materia comercial y económica, algo totalmente demostrable con las reformas del año 2019 en donde se establecen nuevas conductas como estafas agravadas y la responsabilidad penal de las personas jurídicas, sin embargo, este avance no siempre se encuentra acorde al avance doctrinario en el Derecho Penal. En el presente artículo se analizan brevemente los elementos esenciales del tipo penal de estafa, en contraposición con las principales modalidades de estafa agravada, abarcando la responsabilidad penal de las personas jurídicas y haciendo una reflexión respecto a la necesidad de un mayor desarrollo jurisprudencial que merece este tipo penal.
Valorización social del patrimonio arqueológico para un desarrollo turístico de la provincia de Petorca
Authors: Muñoz Alan , Araneda Felipe , Ostria María Soledad
Published: November 2021

El objetivo de este estudio apunta a identificar aspectos relevantes para la construcción de un modelo de desarrollo turístico en la provincia de Petorca, para lo cual se analizaron los bienes arqueológicos existentes en el territorio, la valorización social de los mismos por parte de la comunidad, y el grado de adecuación de dichos bienes para ser utilizados en la actividad turística. Además, se hizo una revisión de teorías y literatura asociadas a estas áreas, lo que permitió generar una base de conocimiento para discutir acerca del desarrollo del territorio considerando los resultados obtenidos. El trabajo se fundamentó en una metodología de enfoque mixto, con técnicas de campo y entrevistas a actores locales. Como resultado se obtuvo una alta valorización de los habitantes acerca de su patrimonio arqueológico, pero un nivel de adecuación inicial para uso turístico de estos mismos bienes, lo que permite plantear algunas orientaciones para la construcción de un modelo de desarrollo turístico basado en el patrimonio arqueológico.
Psychodrama technique in enhancing communications skills among Special Education Integration Program (SEIP) students in Malaysia: a case study
Authors: Hashim Siti Khadijah , Bakar Abu Yazid Abu
Published: November 2021

This study aimed to determine the effectiveness of psychodrama technique in enhancing social   interaction among Special Education Integration Program (SEIP) students in Malaysia. The objectives of the     study were to train SEIP students to communicate well through psychodrama, to increase self-confidence when communicating and to expose students to self-management through  psychodrama. The study was conducted via group session on a psychoeducational program   involving 13 students with different learning disabilities at Sekolah Kebangsaan Taman Seri Mawar, Negeri Sembilan. The results show that SEIP students knew the knowledge on how to manage themselves but still need to be improved in terms of communication skills and social   interaction in groups.
A Festa das Tendas
Authors: Ploeg Roberto van der
Published: November 2021

Participando do VI Encontro Intereclesial das Comunidades Eclesiais de Base, em Trindade (GO), duas imagens sempre vinham à minha mente. Sobretudo pela parte da manhã, quando a gente em quatro plenários discutia e refletia sobre vários temas, sentados em improvisados ranchos de palha ou — como a gente diz no Nordeste — em palhoças, tendas de alegria e muito forró...
CEBs: Quando a vivência da fé remexe o senso comum dos pobres
Authors: Assmann Hugo
Published: November 2021

Antes de entrar no assunto específico desta breve nota, não consigo fugir ao impulso interior de testemunhar que o VI Encontro Intereclesial das CEBs me fortaleceu na certeza de que a profunda espiritualidade dos pobres está irrompendo para dentro das estruturas da Igreja, como força irresistível de renovação...
Caminhos das CEBs no Brasil
Authors: Castanho Amaury
Published: November 2021

Participar do VI Encontro Intereclesial das Comunidades Eclesiais de Base do Brasil, realizado entre os dias 21 e 26 de julho p.p. na pequena e religiosa cidade goiana de Trindade, foi uma experiência válida e original...
THE EFFECT OF FESTIVAL QUALITY ON REVISIT INTENTION: MEDIATING ROLE OF DESTINATION IMAGE IN JEMBER FASHION CARNAVAL, JEMBER, INDONESIA
Authors:   Brawijaya University, Faculty of Administration Science, MT. Haryono 163, Malang, Indonesia, SUPRIONO SUPRIONO , YULIANTO Edy ,   Brawijaya University, Faculty of Administration Science, MT. Haryono 163, Malang, Indonesia
Published: November 2021

This study aims to investigate and explain festival qualities that are applied to festival organizers that affect the destination image and the tourist revisit intention. This research uses a quantitative approach through statistical analysis of PLS-SEM and distributed questionnaires that have been designed to 200 tourists. The findings of this study indicate that the constructs of the variables that shape the quality of the festival, namely program content, convenience, and staff, have a positive and significant effect on the image of the destination. In addition, the relationship between destination image and revisit intention has a positive and significant effect.