bluuebunny/crossref_metadata_2025 huggingface dataset:
Türk Kahvesi Fincanları: Tarihsel ve Kültürel Bir Değerlendirme
Authors: Toker Arzu , Akoğlan Kozak Meryem
Published: November 2024

Zengin tarihi ve kendine özgü hazırlama tarzıyla Türk kahvesi, sıradan bir içecek olmaktan çıkıp kültürel bir sembol haline gelmiştir. Bu benzersiz kahve, Osmanlı İmparatorluğu döneminden başlayarak günümüze kadar çeşitli sosyal ritüellerin ve kültürel pratiklerin merkezi olmuştur. Hazırlanışından sunumuna kadar her aşamada derin sembolik anlamlar barındıran Türk kahvesinin sunulduğu fincanlar bu süreçteki en dikkat çekici unsurlardan biridir. Türk kahvesi fincanları, sadece bir içecek kabı olmanın ötesinde, sosyal statü, estetik değer ve kültürel kimliğin önemli göstergeleri olarak kabul edilmiştir. Fincanların tasarımı, kullanılan malzemeler ve süsleme teknikleri, tarih boyunca değişim göstermiş ve dönemin estetik anlayışını yansıtmıştır. Osmanlı saraylarından halk kahvehanelerine kadar her kesimde farklı özellikler taşıyan kahve fincanları, sosyal ve kültürel hayatın ayrılmaz bir parçası olmuştur. Bu çalışmada, Türk kahvesi fincanlarının tarih içindeki görünümü Osmanlı İmparatorluğu’ndan günümüze kadar olan süreçte incelenmiş, farklı dönemlerde kullanılan fincanların özellikleri ve günümüze nasıl evrildiği de ele alınmıştır.
Algorithms for representing positive odd integers as the sum of arithmetic progressions
Authors:   Department of Mathematical Sciences, University of Nevada, Shiue Peter J.-S. , Shannon Anthony G. ,   Warrane College, University of New South Wales, Huang Shen C. ,   Department of Mathematical Sciences, University of Nevada, Schwob Michael R. ,   Department of Statistics and Data Sciences, University of Texas, Venkat Rama ,   College of Engineering, University of Nevada
Published: November 2024

This paper delves into the historical and recent developments in this area of mathematical inquiry, tracing the evolution from Wheatstone’s representation of powers of an integer as sums of arithmetic progressions to extensions of Sylvester’s Theorem (Sylvester and Franklin, [14]). Sylvester’s Theorem, a result that determines the representability of positive integers as sums of consecutive integers, has been the foundation for numerous extensions, including the representation of integers as sums of specific arithmetic progressions and powers of such progressions. The recent works of Ho et al. [3] and Ho et al. [4] have further expanded on Sylvester’s Theorem, offering a procedural approach to compute the representability of positive integers in the context of arithmetic progressions. In this paper, efficient algorithms to compute the number of ways to represent an odd positive integer as sums of powers of arithmetic progressions are presented.
Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis
Authors: Zhao Zewei , Hu Longyun , Song Bigui , Jiang Tao , Wu Qian , Lin Jiejing , Li Xiaoxiao , Cai Yi , Li Jin , Qian Bingxiu , Liu Siqi , Lang Jilu , Yang Zhonghan
Published: November 2024

The induction of adipose thermogenesis plays a critical role in maintaining body temperature and improving metabolic homeostasis to combat obesity. β3-adrenoceptor (β3-AR) is widely recognized as a canonical β-adrenergic G protein-coupled receptor (GPCR) that plays a crucial role in mediating adipose thermogenesis in mice. Nonetheless, the limited expression of β3-AR in human adipocytes restricts its clinical application. The objective of this study was to identify a GPCR that is highly expressed in human adipocytes and to explore its potential involvement in adipose thermogenesis. Our research findings have demonstrated that the adhesion G protein-coupled receptor A3 (ADGRA3), an orphan GPCR, plays a significant role in adipose thermogenesis through its constitutively active effects. ADGRA3 exhibited high expression levels in human adipocytes and mouse brown fat. Furthermore, the knockdown of
Adgra3
resulted in an exacerbated obese phenotype and a reduction in the expression of thermogenic markers. Conversely,
Adgra3
overexpression activated the adipose thermogenic program and improved metabolic homeostasis without an exogenous ligand supplementation. We found that ADGRA3 facilitates the biogenesis of beige adipocytes through the Gs-PKA-CREB axis. Moreover, hesperetin was identified as a potential agonist of ADGRA3, capable of inducing adipocyte browning and ameliorating insulin resistance. In conclusion, our study demonstrated that the overexpression of constitutively active ADGRA3 or the activation of ADGRA3 by hesperetin can induce adipocyte browning by Gs-PKA-CREB axis. These findings indicate that the utilization of hesperetin and the selectively overexpression of ADGRA3 in adipose tissue could serve as promising therapeutic strategies in the fight against obesity.
A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia
Authors: Kwon Hyo Jun , Santhosh Devi , Huang Zhen
Published: November 2024

Amyloid β (Aβ) forms aggregates in the Alzheimer’s disease brain and is well known for its pathological roles. Recent studies show that it also regulates neuronal physiology in the healthy brain. Whether Aβ also regulates glial physiology in the normal brain, however, has remained unclear. In this article, we describe the discovery of a novel signaling pathway activated by the monomeric form of Aβ in vitro that plays essential roles in the regulation of microglial activity and the assembly of neocortex during development in vivo. We find that activation of this pathway depends on the function of amyloid precursor (APP) and the heterotrimeric G protein regulator Ric8a in microglia and inhibits microglial immune activation at transcriptional and post-transcriptional levels. Genetic disruption of this pathway during neocortical development results in microglial dysregulation and excessive matrix proteinase activation, leading to basement membrane degradation, neuronal ectopia, and laminar disruption. These results uncover a previously unknown function of Aβ as a negative regulator of brain microglia and substantially elucidate the underlying molecular mechanisms. Considering the prominence of Aβ and neuroinflammation in the pathology of Alzheimer’s disease, they also highlight a potentially overlooked role of Aβ monomer depletion in the development of the disease.
Expanding the toolbox: Novel class IIb microcins show activity against Gram-negative ESKAPE and plant pathogens
Authors: Mortzfeld Benedikt M , Bhattarai Shakti K , Bucci Vanni
Published: November 2024

Interspecies interactions involving direct competition via bacteriocin production play a vital role in shaping ecological dynamics within microbial ecosystems. For instance, the ribosomally-produced siderophore bacteriocins, known as class IIb microcins, affect the colonization of host-associated pathogenic
Enterobacteriaceae
species. Notably, to date, only five of these antimicrobials have been identified, all derived from specific
Escherichia coli
and
Klebsiella pneumoniae
strains. We hypothesized that class IIb microcin production extends beyond these specific compounds and organisms. With a customized informatics-driven approach, screening bacterial genomes in public databases with BLAST and manual curation, we have discovered twelve previously unknown class IIb microcins in seven additional
Enterobacteriaceae
species, encompassing phytopathogens and environmental isolates. We introduce three novel clades of microcins (MccW, MccX, and MccZ), while also identifying eight new variants of the five known class IIb microcins. To validate their antimicrobial potential, we heterologously expressed these microcins in
E. coli
and demonstrated efficacy against a variety of bacterial isolates, including plant pathogens from the genera
Brenneria, Gibbsiella, and Rahnella
. Two newly discovered microcins exhibit activity against Gram-negative ESKAPE pathogens, i.e.
Acinetobacter baumannii
or
Pseudomonas aeruginosa
, providing the first evidence that class IIb microcins can target bacteria outside of the
Enterobacteriaceae
family. This study underscores that class IIb microcin genes are more prevalent in the microbial world than previously recognized and that synthetic hybrid microcins can be a viable tool to target clinically relevant drug-resistant pathogens. Our findings hold significant promise for the development of innovative engineered live biotherapeutic products tailored to combat these resilient bacteria.
Learning and cognition in a decision made at reflex speed
Authors: Krause Martin , Schulze Wolfram , Schuster Stefan
Published: November 2024

In recent years it has become clear that many decisions do not obey the rule that more time yields better decisions. These decisions can be made remarkably fast and yet accurately, sometimes based on very limited information. It is presently unclear whether such ‘blink’ or high-speed decisions lack cognitive aspects that only much slower ‘deliberative’ decision-making can support. Here we demonstrate an unexpected degree of flexibility and cognition in a decision made by a hunting animal at reflex-like speed. Based on observing initial speed, direction, and height of falling prey archerfish decide in just 40 milliseconds on a turn toward the later ballistic landing point. This enables the fish to dash off to arrive simultaneously with prey and to secure it against numerous competitors. We established an approach that allowed us to replace ballistics, the rule that governs the turn decisions, with a novel rule of how to connect the input variables with the rewarded turns. This approach revealed that the fish are not using a hardwired circuit but were able to reprogram their decision in efficient ways that allowed them to immediately generalize to untrained settings. Training even allowed the decision to simultaneously use two distinct sets of rules, one for each of two distinct objects. The flexibility of the decision and the occurrence of high-level cognitive features are counterintuitive for a reflex-like decision made faster than an Olympic sprinter can respond to the start gun. However, they imply that combining speed and accuracy in rapid decisions does not generally make them less smart than decisions made over far longer timescales.
Malabarismo de identidades: Interpretando prácticas profesionales transnacionales en colegios chilenos
Authors: Weinmann Michiko , Neilsen Rod , Veliz Leonardo , Naveas Alejandro
Published: November 2024

Los programas de movilidad global dirigidos a estudiantes de pedagogía constituyen un componente integral de diversas experiencias en formación docente. Se conciben como oportunidades de desarrollar habilidades que respondan a aulas progresivamente multilingües y multiculturales. Sin embargo, tales programas pueden perpetuar estereotipos culturales, además de fomentar sentimientos de superioridad y legitimización. Este artículo representa un análisis de las experiencias de futuros profesores australianos en un programa de movilidad en Santiago, Chile. Dicho análisis tiene dos objetivos: en primer lugar, contribuir a la comprensión actual del transnacionalismo; y en segundo lugar, examinar cómo las categorías binarias de la identidad cultural propia y del otro continúan moldeando los encuentros interculturales. De aquí surge la necesidad de apoyar a los futuros profesores a encontrar nuevas formas discursivas para abordar la complejidad de sus experiencias.
O baixo crescimento econômico brasileiro: sua relação com as instituições e a democracia
Authors: Acar Tatiana , Arruda Neto Gerson de , Souza Luiz Gustavo Antonio de
Published: November 2024

Desde a redemocratização brasileira em 1985, observa-se um baixo crescimento econômico com média de apenas 2,33% ao ano até 2020. Este trabalho propõe-se a explicar, através de duas teorias institucionais, como o quadro institucional brasileiro figurado após a redemocratização tem freado o crescimento econômico do país. Para tal, utilizou-se da metodologia de pesquisa explicativa, a fim de apresentar as teorias institucionais de Douglass North e de Daron Acemoglu e James Robinson, de forma a compreender a dinâmica institucional por trás do desempenho econômico dos países; correlacionar suas teorias com os conceitos de democracia e crescimento econômico; entender de que forma o quadro institucional brasileiro fora configurado a partir da redemocratização, bem como buscar responder se as instituições são a origem do fraco desempenho econômico do Brasil; e, por fim, explanar possíveis mudanças institucionais, a fim de mudar o modo de agir do Estado brasileiro para promover uma aceleração no crescimento econômico. Quanto aos principais resultados, verificou-se a relevância de impacto do quadro institucional brasileiro no baixo crescimento da economia desde 1985, quadro este que levou a um modelo econômico de baixo crescimento com redistribuição dissipativa, elevando os gastos fiscais e, por conseguinte, a carga tributária, além de outras distorções econômicas.
Desafios e resiliência das cooperativas de consumo: uma análise global com foco no Brasil (1995-2023)
Authors: Ribas Walter Perpétuo , Freitas Júnior Miguel Archanjo de
Published: November 2024

O presente estudo analisa o desenvolvimento e os desafios enfrentados pelas cooperativas de consumo no mundo, buscando compreender os motivos que levaram a uma redução significativa do número de cooperativas de consumo no Brasil. Para atingir este objetivo, optou-se em realizar uma revisão sistemática, com buscas na base de dados Scopus, abrangendo as publicações realizadas entre os anos 1995-2023. A análise deste material revelou que em diversos países, as cooperativas de consumo conseguiram manter prosperidade e perenidade no mercado de varejo, devido à realização de ações, como a promoção de uma governança mais inclusiva e participativa, aliada a estratégias inovadoras de gestão, que ajudaram a superar os desafios de um mercado cada vez mais competitivo e individualista. No Brasil, os estudos demonstram que houve uma queda significativa do número de cooperativas de consumo. O objetivo geral do presente estudo é identificar qual foi o principal fator determinante que colabou decisivamente para a derrocada do cooperativismo de consumo brasileiro. Observou-se nos estudos que as cooperativas de consumo desempenham um papel crucial na promoção de um modelo de economia mais equitativo e resiliente, pois os consumidores têm voz ativa e se beneficiam diretamente dos resultados financeiros da organização. No entanto, para se manterem competitivas no mercado atual, é necessário que adotem estratégias inovadoras e reafirmem seu compromisso com os princípios cooperativos. A pesquisa revela que, apesar das condições adversas, as cooperativas de consumo têm potencial para se manter no mercado, promovendo a inclusão social e o desenvolvimento econômico local.
New Modified Efficient Variance Estimators for the Estimation of Population Variance in Survey Sampling
Authors: Bhat M A
Published: November 2024

For efficient and precise estimate of population variance, we have proposed some new ratio type variance estimators in the current research work by incorporating the linear combination of conventional and non-conventional parameters of auxiliary information. Bias and mean square error have been computed up to the first order of approximation. Numerical demonstration has been carried out to test the efficiency of new proposed estimators against existing estimators.
Efficient Handling of Non-response in Sample Surveys: Development of Ratio-type Variance Estimators
Authors: Bhat M.A.
Published: November 2024

The present study has been under taken to address the issue of presence and absence of non-response problems in Sample surveys. We have developed some new efficient ratio-type variance estimators for the computation of the finite population variance in presence and absence of non-response, by incorporating Positional parameters as auxiliary information. The expression for mean square errors of proposed estimators has been derived up to the first order of approximation. To test the efficiency of new developed estimators, practical demonstration has been carried to ascertain the performance of suggested Estimators.
The Effect of Project-Based Learning Models and Digital-Based Learning Media on Students' Work Skills in Accounting Subjects in SMK Negeri 1 Gorontalo City, Indonesia
Authors: Kalapati Rahayu Putri Ayu , Canon Syarwani , Panigoro Meyko , Hafid Radia , Niswatin
Published: November 2024

Project Based Learning (PJBL) is a learning model that uses projects/activities as a means of learning to achieve attitude, knowledge and skill competencies. PJBL learning with the use of digital-based learning media is considered very important in improving student skills, especially in the digitalisation 4.0 era. This study aims to analyse the effect of using project-based learning models and digital-based learning media on student work skills in accounting subjects at SMK Negeri 1 Gorontalo City. This research uses a quantitative approach with causality. The type of data in this study is primary data through distributing questionnaires to students who are research samples to assess the effectiveness of learning using project-based learning models and digital-based learning media. The number of samples in this study were 156 students. The data analysis technique used is Multiple Regression with the help of SPSS version 21. The results of this study indicate that (1) the Project Based Learning (PjBL) learning model has a positive and significant effect on the work skills of students majoring in Accounting in Vocational High School (SMK) Negeri 1 Gorontalo City. (2) Digital-based learning media has a positive and significant effect on the employability skills of students majoring in Accounting in Gorontalo City. Based on these results, it can be a recommendation that the project-based learning model and digital-based learning media can be combined in order to increase student creativity in learning activities.
Constraints Faced by Bt Cotton Seed Companies in Gujarat: A Comprehensive Analysis
Authors: Nariya Y. H. , Bharodia C. R. , Maheta H. Y. , Kumar Kalpesh , Patel D. J. , Kumar Niraj
Published: November 2024

India's cotton industry is crucial to the economy, providing raw material for 75% of the textile industry and employing millions. Despite having the largest area under cotton cultivation globally, India faces challenges such as low productivity due to rain-fed farming. To address these challenges by enhancing productivity and pest resistance the Bt cotton producer companies were facing different constraints. Data from various stakeholders in Gujarat's Bt cotton seed market was collected and analysed using the Garrett Ranking Method to identify key factors influencing sales. The findings highlight the major constraints faced by Bt cotton producer companies includes the fixed price policy, lack of skilled manpower and seed adulteration. By improving access to quality seeds, enhancing farmer awareness and reforming seed policies, which significantly helps market dynamics in shaping the cotton seed sector.
Assessment of Safety Programmes on Employee Productivity in the Oil and Gas Industry in the Niger Delta Area, Nigeria
Authors: Tsado Sala, Lazarus , L. Nwaogazie, Ify , N. Ugbebor, John
Published: November 2024

This study evaluates the effectiveness of safety programmes on employee productivity in Indigenous and Multinational Oil and Gas companies in the Niger Delta. Key safety constructs—management commitment, safety participation, safety compliance, safety promotional policies, safety training, safety knowledge, and employee involvement—are assessed for their impact on productivity. Data from structured questionnaires were analyzed using descriptive statistics and reliability tests. The findings reveal that Multinational companies generally exhibit stronger positive correlations between safety constructs and productivity compared to Indigenous companies, suggesting more effective safety management systems in Multinational firms. For instance, management commitment shows a stronger correlation with productivity in Multinational companies (r = 0.35) than Indigenous firms (r = 0.15). The study concludes that Indigenous companies could improve productivity by adopting more structured safety frameworks and enhancing employee engagement and training programmes. Indigenous companies could explore underlying factors, such as better resources, more rigorous safety standards, or stronger organizational cultures across all the safety constructs to further enhance productivity.
Processing, Value Addition and Post-Harvest Technology of Tomato: A Scoping Review on Global and Indian Perspective
Authors: Kaundal Munish , Sharma Keshav , Anand Harshit
Published: November 2024

India, with its favorable climatic conditions, is a major producer of tomatoes, ranking second globally. However, the tomato processing sector in India is underdeveloped, with only 1% of the produce being processed compared to developed nations such as Italy (64.02%), Spain (39.41%) and the United States (10.34%). Of the more than 180 million tonnes of tomatoes produced annually, around 40 million tonnes are processed. India's substantial tomato output, which occurs primarily in the winter, has made it a prominent participant in the global tomato processing industry. This would help the Indian market utilize tomato-based goods throughout the off-season. Lycopene, a beneficial compound, is found to be higher in processed tomato products compared to fresh tomatoes. Prominent companies in the Indian tomato processing industry include Hindustan Unilever, Nestle India, Mother Dairy, and Dabur India. Despite the potential, the sector faces challenges such as inadequate processing facilities and limited varieties suitable for processing, leading to substantial post-harvest losses. The demand for tomato-processed products in India has been increasing at 30% annually in recent years, with a rising variety of products being offered. Increased support, improved supply chain management, and adoption of advanced processing techniques could reduce wastage, add value, and enable India to become a prominent player in the global tomato processing industry. With the adoption of modern technologies such as automated sorting, grading, and cold storage facilities, the efficiency of the tomato processing industry can improve. This would reduce post-harvest losses and ensure better quality control.
Evaluation of Genotypes against Water Stress and Salinity in Rice (Oryza sativa L.)
Authors: N Veronica , P Venkata Ramana Rao
Published: November 2024

Abiotic stresses pose significant challenges to growth, yield and productivity thus threatening food security. Hence, it is essential to develop climate resilient rice varieties that mitigate the impact of abiotic stress. A study on physiological characterization for water and salinity stress was conducted in twenty-eight rice genotypes during kharif 2023 at Regional Agricultural Research Station, Maruteru. Among all the treatments, root length, shoot length, root and shoot dry weight and chlorophyll content was maximum under control followed by 1% mannitol, 2% mannitol and salinity stress. Visual scoring for water stress at seedling stage revealed that under mild water stress (1% M) more than 90% of plants survived in genotypes viz., AC-35678, FL 478, Ravana, Rahaspunjar, AUS 63, AUS 73, Vandana, NICRA 16, NICRA 17, CR-3439-4-E-17-2-1-B-1-S-1, CR-4215-2-5-2-M-4-SUB-2-5-1. Under severe water stress (2% M) more than 70% of the seedlings survived in NICRA 16, CR-4215-2-5-2-M-4-SUB-2-5-1, CRAC-4423-3, IET -18727, IC-516 149, IET-18716, AC-35678, FL 478, AC 85, Rahaspunjar, AUS 100, NICRA 17, CR-3439-4-E-17-2-1-B-1-S-1. Under salinity stress the score 3 was recorded in FL 478, and 5 in Rahaspunjar, IET -18727, NICRA 16, Ravana, NICRA 17. For both combined stresses, FL 478, Rahaspunjar, NICRA 16 and NICRA 17 were identified as tolerant and can be identified as donors for development of rice varieties having climate resilience.
A Comparative Study of the Physio-Mechanical Properties of Iron Fillings and Mild Steel Chips in Reinforced Particleboard
Authors: Alozie Uchenna , Mba Bethel , M. A Allen , Omonini Clifford , Nwoziri S. C. , Onwuka Franklin , Muhammed Sani Habeeb , Samson Amalime Chukwudi
Published: November 2024

This study compared the physio-mechanical characteristics of mild steel chips and iron fillings on sawdust-produced particleboard to regular particleboard made from sawdust alone, using identical production conditions. Particle board was made using 1.18mm sawdust, 3mm mild steel chips, and iron filler with diameters of 0.15mm, 0.425mm, 0.6mm, 1.18mm, and 2.0mm. 70g of sawdust, 40g of iron fillings, and 40g of mild steel chips were used in the production process. 50ml urea formaldehyde was used as a binder. The atomic absorption spectroscopy was determined for iron fillings and mild steel chips. Particleboards were produced at a temperature of 160°C and a pressure of 20 tons for 15 minutes. Mechanical property tested indicates that particleboard containing iron filings has a lower Modulus of rupture (MOR) because the size of the iron filings in the particleboard reduces as the MOR increases. The particle size of iron filling with the value of 2.0mm had the least MOR of 3.99mpa/m2 in iron filling samples. The MOR of Mild steel chips was higher compared to all the samples analyzed. Modulus of Elasticity (MOE) of particleboard produced from iron filings increases as the particle sizes of iron filings increases. The samples containing iron filings alone showed the highest MOE of 244.89 MPa/m2 for 2.0 mm particle board, while the ones containing mild steel chips had the highest MOE of 282.82 MPa/m2 across all samples, suggesting their strength as reinforcement. The rate of water absorption and thickness of swell of particleboard produced from iron filings increases as the size of the iron fillings increase.
The Role Of Cooperatives In Enhancing Women’s Empowerment In Rural India
Authors: Minzar Mohammed , Mishra Manish Kumar
Published: November 2024

This study explores the role of cooperatives in enhancing women’s empowerment in rural India through a comprehensive analysis of secondary data. Cooperatives have emerged as a powerful tool for rural women, providing them with economic opportunities, social capital, and political influence. The research focuses on key indicators, including the female labour force participation rate (LFPR), access to finance, leadership roles, and participation in local governance. Data from various sources, including government reports and research publications, highlight that while cooperatives significantly contribute to women’s economic independence and social empowerment, challenges remain. Cultural barriers, lack of formal education, and restricted access to financial resources continue to hinder the full participation of women in cooperatives, particularly in states like Bihar and Uttar Pradesh. The study finds that states with better cooperative frameworks, such as Kerala and Tamil Nadu, exhibit higher participation rates and greater empowerment outcomes. Recommendations include enhancing financial literacy programs, promoting gender-sensitive policies, and improving cooperative infrastructure in underserved regions. These findings underscore the importance of cooperatives as a vehicle for holistic empowerment, but also emphasize the need for tailored regional interventions to address persistent barriers
Influence Of Metabolic Syndrome On Functionality And Cognition In Elderly People
Authors: Almeida Taianara Tocantins Gomes , Carvalho Elenilce Pereira De , Luna Pricila Ferreira de
Published: November 2024

Background: In the aging process, physiological changes occur that increase the elderly person's potential to develop Metabolic Syndrome (MS) and lead to a decrease in functional and cognitive capacity. Thus, the objective was to associate the presence of Metabolic Syndrome with the functional and cognitive capacity of elderly patients receiving outpatient care. Materials and Methods: A cross-sectional study was conducted with elderly individuals receiving care at the nutrition outpatient clinic of a university hospital. The NCEP-ATP III criteria were used to diagnose Metabolic Syndrome. Nutritional status was determined by Body Mass Index (BMI). Functional capacity was assessed through Activities of Daily Living (ADLs) using the Katz Index, and Instrumental Activities of Daily Living (IADLs) using the Lawton and Brody scale. The Mini-Mental State Examination (MMSE) was used for cognitive assessment. Results: The sample consisted of 144 elderly individuals, mostly women (72.2%). All participants were classified as independent for ADLs and 82.63% for IADLs. The majority did not show cognitive deficits according to the MMSE (86.7%). There was no statistically significant correlation between the variables of Metabolic Syndrome and the MMSE. However, there was significance (p=0.001) between Metabolic Syndrome and nutritional status, as well as between the means of Waist Circumference, HDL-C, and systolic blood pressure. Conclusion: The components of Metabolic Syndrome were relevant to excess weight, but there was no significance for cognitive and functional deficits among the elderly participants in the study
A Importância Das Tecnologias Para O Ensino Em Libras Nas Escolas
Authors: Soares D’’Jullian Glay Pereira , Silva Conceição Rosa Dos Santos , Junior Waldyr Barcellos , Silva Clécio José Da , Souza Josenete Trajano De
Published: November 2024

Este estudo teve como objetivo analisar a importância das tecnologias para o ensino de LIBRAS nas escolas, utilizando uma abordagem qualitativa e exploratória. A amostra foi composta por quinze professores, selecionados por conveniência, que participaram de entrevistas em profundidade sobre suas experiências com a integração de tecnologias no ensino. Os resultados revelaram que, apesar dos benefícios, como a facilitação do aprendizado e a promoção da inclusão, existem desafios, como a falta de formação adequada e a resistência à mudança por parte de alunos e educadores. A análise indicou que a tecnologia deve ser vista como uma parte integrante da estratégia pedagógica, sendo essencial para promover uma educação inclusiva e de qualidade. Em conclusão, a pesquisa destaca a necessidade de formação contínua para professores e um compromisso coletivo para maximizar o potencial das tecnologias no ensino de LIBRAS, contribuindo para uma sociedade mais equitativa
Chorioretinitis Sclopetaria
Authors: . ..
Published: November 2024

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A Perspective On A Promising Role For Caffeine In Modulating The Casr In Pancreatic Β-Cells
Authors: MYG Younis , Don Nadee N. J. Matarage , Ahn Young-Hoon
Published: November 2024

The extracellular calcium-sensing receptor (CaSR) is a G-protein-coupled receptor (GPCR) that plays a crucial role in the parathyroid glands and kidneys in maintaining calcium (Ca2+) homeostasis. The extracellular CaSR is present in various cell types not implicated in controlling plasma Ca2+ levels. There is accumulating evidence that CaSR plays a significant role in regulating the function of β-cells in the pancreas. Divalent cations and insulin are released together during exocytosis, and their concentration in the restricted intercellular compartments of the pancreatic islet increases to activate CaSR in neighboring cells. Subsequently, the activated CaSR stimulates insulin vesicle release in the adjacent cells, and by repeating these steps, the signal is amplified in the whole islet. Recent work developed a photoaffinity-tagged glutathione derivative (DAZ-G) as a chemical tool. The study demonstrated that DAZ-G can identify and analyze CaSR ligands. The use of DAZ-G identified caffeine as a positive allosteric modulator of the CaSR, suggesting that the physiological effects of caffeine are partly attributed to its stimulation of the CaSR. Future work may utilize caffeine to activate the CaSR in pancreatic β-cells to improve their secretory function
The Diagnostic And Prognostic Role Of Immunohistochemistry In Head & Neck Tumours Along With Radiological & Histopathological Study
Authors: Patel Dr. Priya J. , Patel Dr. Minaxi J. , Dave Dr. Darshan D. , Dave Dr. Neeru D.
Published: November 2024

Background: Head & neck tumors are defined as benign, premalignant & malignant tumors above the clavicles, except the tumors of brain, spinal cord and esophagus. This includes tumors of paranasal sinus, nasal cavity, salivary glands, thyroid and upper aerodigestive tract, lymph nodes of neck, skin & its appendages, soft tissue tumors, midline carcinomas & metastatic tumors. Ultrasonography, computed tomography, magnetic resonance imaging were the modalities for initial evaluation. Histopathology was the GOLD standard for diagnosis followed by IHC for confirmation because correct diagnosis & cancer subtyping of the neoplasia is essential for successful therapy and prognosis. Materials & Methods: Study was conducted for 2 years with 100 specimens of head & neck tumors. Thorough Radiological investigation was done followed by Histopathological examination including biopsy & whole resected specimens. IHC markers appropriate to the histopathological diagnosis was done. Results: Among 100 patients of head & neck tumors, most belonged to 5th decade with male: female ratio of 2.3:1. Squamous cell carcinoma (66%) followed by Lymphoma(11%), tumors of salivary glands(8%), metastatic lymphadenopathy(7%) were the lesions present. SCC was most common carcinoma in oral cavity, larynx, nasopharynx and ear with positive p63 marker. 1 case of Basal cell carcinoma with positive BerEP4 & in NHL, salivary gland tumors & Metastatic lymphadenopathy panel of IHC were included for confirmation. Conclusion: Immunohistochemistry has a diagnostic & prognostic role in Head & Neck tumors along with Radiological & histopathological examination.
Transperineal Ultrasound In Clinically Diagnosed FistulaIn Ano Cases - A Cross-Sectional Study In A Tertiary Care Center
Authors: Reddy H Dr. Bharath , P J Dr. Rohan , George Dr. R A , R Dr. Nagesh
Published: November 2024

Fistula-in-ano (FIA) is a chronic and often recurrent anorectal condition characterized by an abnormal communication between the rectum or anal canal and the perianal skin. Accurate diagnosis and management of FIA remain challenging due to the complexity of fistula tracts and potential complications. Traditional diagnostic methods like clinical examination and fistulography are commonly employed, but these methods often lack detailed visualization of the fistulous tracts. In recent years, transperineal ultrasound (TPUS) has emerged as a non-invasive, radiation-free, and cost-effective tool in the assessment of FIA. This study aims to review the role of transperineal ultrasonography in the assessment of fistula-in-ano, with respect to its current techniques, advantages, clinical applications, and future directions.
Interseção Entre Educação Ambiental, Políticas Públicas E Os Objetivos De Desenvolvimento Sustentável (ODS)
Authors: Farias Sidinei , Marques Francisco Roldineli Varela , Filho Abel Martins , Resende Cibele Caetano , Pereira Andreia Cabral Colares
Published: November 2024

Esta pesquisa teve como objetivo analisar a interseção entre educação ambiental, políticas públicas e os Objetivos de Desenvolvimento Sustentável (ODS), empregando uma metodologia baseada na revisão bibliográfica para consolidar informações de diversas fontes acadêmicas e científicas, como SciELO, Scopus e Google Acadêmico. A pesquisa revelou que tanto as políticas públicas quanto a educação ambiental são fundamentais e complementares na promoção dos ODS. As políticas públicas fornecem um quadro regulatório essencial para práticas sustentáveis e inovação tecnológica, enquanto a educação ambiental é crucial para conscientizar e capacitar indivíduos e comunidades a adotar práticas sustentáveis. A análise dos textos mostrou que a integração eficaz dessas duas áreas pode maximizar os impactos positivos em direção a um desenvolvimento sustentável, abordando desafios como a gestão de recursos naturais e a adaptação às mudanças climáticas. A conclusão destaca que a colaboração entre governos, instituições educacionais e a sociedade civil é vital para superar desafios e promover um futuro sustentável e justo, evidenciando que a combinação de políticas robustas e educação ambiental é chave para alcançar os ODS.
A Study On Financial Practices In Micro And Small Scale Business
Authors: Ali Mohammad Murtuza , Begum Samdani
Published: November 2024

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Inclusive Virtual Conciliation Hearings: The Role Of The Judiciary In Ensuring Accessibility
Authors: Reis Carla Regina Nunes Dos Santos , Perius Oneide
Published: November 2024

This study explores the evolution and effectiveness of virtual conciliation hearings in the context of the current legal system. It analyzes how these hearings have been adapted to include participants with different needs, emphasizing the role of the Judiciary in promoting accessibility. The review covers the technological changes, legal adaptations and inclusive practices implemented to ensure that all citizens, regardless of their physical, sensory or cognitive limitations, can fully participate. The work draws on a variety of scholarly sources, including comparative law studies, research on assistive technologies, and public policy analysis. The method adopted includes the qualitative analysis of data from different jurisdictions, focusing on how legislation and judicial practices have been adapted to meet accessibility needs in a virtual environment. The results indicate a growing trend in the adoption of virtual conciliation hearings as a means of making the judicial system more accessible. There is evidence that while there are significant challenges, especially in terms of access to appropriate technology and training of legal users and practitioners, there are considerable advances. Inclusive policies and the use of assistive technologies have proven to be fundamental to ensuring accessibility, with positive impacts on the efficiency and equity of the judicial system
Digital Transformation In Business - The Impact Of AI In Enhancing Customer Experience
Authors: Bharatkumar Sukhiyaji Riya
Published: November 2024

Background: This study investigates how artificial intelligence (AI) enhances customer experience as part of digital business transformation. With businesses increasingly relying on AI for personalization and real-time engagement, this research seeks to understand AI's role in improving customer satisfaction, particularly in service areas like social media marketing and call centers. Materials and Methods: The research uses a secondary research approach, analyzing literature and reports from 2018 to 2024. Data was gathered from peer-reviewed articles, case studies, and industry reports, and thematic analysis was applied to identify the key impacts of AI on customer experience. Results: The findings reveal a positive correlation between AI and improved customer experience, with AI accounting for 26.4% of the variance. Key benefits include personalized services (22.9%) and better after-sale support (7%). AI has also reduced waiting times and improved real-time engagement, particularly in customer service. Conclusion: AI offers significant benefits for enhancing customer experience, but the challenges remain, including adoption barriers and privacy concerns. This study concludes that balancing technological advancements with ethical considerations is crucial for successful AI integration
Práticas Pedagógicas Baseadas Em Jogos Para O Desenvolvimento Da Linguagem Na Educação Infantil
Authors: Silva Marcelo José Da , Carrero Sérgio Fernando , Júnior Paulo Cesar Lavrador , Lima Odaize Do Socorro Ferreira Cavalcante , Lima Agnaldo Braga
Published: November 2024

As práticas pedagógicas têm se mostrado um campo extremamente fértil para a aplicação de jogos como ferramenta no desenvolvimento da linguagem em crianças em idade pré-escolar. O uso de jogos como metodologia pedagógica é uma abordagem que, além de ser lúdica e atrativa para as crianças, possui grande potencial para facilitar o aprendizado de habilidades linguísticas de maneira significativa. Ao utilizar o jogo como estratégia de ensino, os educadores conseguem criar um ambiente de aprendizagem mais interativo e dinâmico, no qual as crianças são incentivadas a se comunicar, negociar regras, criar narrativas e participar ativamente do processo de construção do conhecimento. Diversos estudos têm demonstrado que a inserção de jogos no currículo educacional infantil promove avanços no desenvolvimento da linguagem oral e escrita, ao mesmo tempo em que fomenta a interação social entre os alunos. A linguagem, sendo uma das principais ferramentas de comunicação e expressão, é essencial para o desenvolvimento cognitivo e social das crianças, e o jogo possibilita uma abordagem natural e espontânea para a assimilação de conteúdos complexos. As atividades lúdicas permitem que as crianças adquiram novas palavras, desenvolvam o vocabulário, construam frases mais elaboradas e compreendam melhor o uso da linguagem em diferentes contextos. Além de representar um meio de entretenimento, o jogo no contexto da educação infantil desempenha um papel fundamental na
Exploring Stressors And Their Associated Effects On Workplace Stress In The Ministry Of Interior United Arab Emirates
Authors: Albusaeedi Dr. Jameela Khalfan Almur
Published: November 2024

Stress is a psychological and physical mental disorder that occurs in situations of pressure, which requires available resources to meet organizational and individual demands. This research was about exploring stressors and their effects associated with workplace stress. A mixed method exploratory sequential approach and survey were used to describe Ministry of Interior (MOI) employees'' workplace stress and its stressors that involved two phases: qualitative (phase I) used interviews and quantitative (phase II) used surveys to explore stressors and its effects associated with the workplace stress. This study aimed to explore stress prevalence and the stressors experienced by MOI employees. Qualitative and quantitative analysis is carried out on the collected data. The result of phase I indicated that if there were more frequent stress symptoms among the participants, this would contribute to decreased productivity. Phase II of the analysis relied on the multiple regression technique, Stress Management Conflict Resolution predicts that was statistically significant, which was shown as the R-squared, the overall regression model was significant, F (3,296) =0.14, P > .025, R2 =.014. Workplace stress, the multiple regression model was significant, F (3,296) =98, P > .403, R2 = 98. Absenteeism, F (3,296) =.27, P > .80, R2 = 84. Workload and Responsibility - NIOSH's multiple regression model was significant, F (3,296) =85, P > .85, R 2 = 85 on predicting job satisfaction. The confidence level in the finding was high since the P-value was less than the maximum acceptable value of 0.05. Therefore, the F-statistic was significant.
Pilot Plants
Authors: Gertenbach Dennis
Published: June 2018

Pilot plants play a key role in the development of new chemical processes, providing the necessary bridge between the laboratory experiments that define the process flow sheet and the design and operation of the commercial plant. Pilot plants can also provide smaller quantities of product for customer evaluation, regulatory requirements, and/or for animal and human trials. Experience has shown that shortcutting the pilot plant step greatly increases the risks of commercializing a new process. In contrast, a well‐planned pilot plant program can significantly reduce these risks.
Ultrathin Metal–Organic Framework: An Emerging Broadband Nonlinear Optical Material for Ultrafast Photonics
Authors: Jiang Xiantao , Zhang Liangjing , Liu Shunxiang , Zhang Yiyue , He Zhiliang , Li Wenjia , Zhang Feng , Shi Yihuang , Lü Wei , Li Yu , Wen Qiao , Li Jiagen , Feng Jun , Ruan Shuangchen , Zeng Yu‐Jia , Zhu Xi , Lu Yuerui , Zhang Han
Published: June 2018

Crystalline porous metal–organic frameworks (MOFs) with nanometer‐sized void spaces, large surface areas and ordered reticular motifs have offered a platform for achieving disruptive successes in divisional fields. Great progress in exploring the linear and nonlinear optical features of MOFs has been achieved, yet third‐order optical nonlinearities in two‐dimensional (2D) MOFs have rarely been studied. Here, a broadband nonlinear optical amplitude modification and phase shift are demonstrated in a few‐layer nickel‐p‐benzenedicarboxylic acid MOF (Ni‐MOF). The calculated bandgap of Ni‐MOF decreases from 3.12 eV to 0.85 eV as the doping of Ni ions increases, indicating the ability of this material to be used for optical amplitude modulation from the visible to the near‐infrared region, which is experimentally confirmed via a Z‐scan technique. The determined third‐order optical nonlinearities resemble those of other low‐dimensional nonlinear optical materials, suggesting the wide potential of Ni‐MOF for application in optoelectronics. As an example, a Ni‐MOF‐based saturable absorber was implemented into fiber resonators to demonstrate its broadband mode‐locking operations. A femtosecond laser pulse was readily obtained in the telecommunication wavelength window in an integrated all‐fiber resonator. Considering the chemical compatibility and rich variability, these primary investigations pave the way towards advanced photonics based on multifeature MOF materials.
Balanced occlusion aided locator abutment retained overdenture with no implant placed within anterior region: A case report
Authors: Chu Shunli , Guo Tianqi , Zhu Ting , Zhou Yanmin
Published: June 2018

Key Clinical Message

A maxillary edentulous arch with severe bone resorption was treated by locator abutment retained overdenture. Under the criterion of balanced occlusion, implants located solely in the posterior area is a good selection which could efficiently guarantee the stability and perdurability of the overdenture in 2‐year follow‐up.
Aortic root ectasia as a phenotypic feature of a mitochondrial disorder
Authors: Finsterer Josef
Published: June 2018

Key Clinical Message

Mitochondrial disorder (MID) can be suspected upon application of the mitochondrial multiorgan disorder syndrome score; aortic root ectasia (ARE) can be a phenotypic feature of MIDs; ARE in a MID may result from affection of vascular smooth muscle cells by the metabolic defect; ARE requires long‐term follow‐up not to miss the point at which ARE transforms to an aneurysm requiring vascular surgery.
Common Carbons as Water‐Reducing Catalysts in Photo‐Driven Hydrogen Evolution with Nitrogen‐Dependent Activity
Authors: Gottlieb Eric , Kagalwala Husain N. , Mohin Jacob , Budwal Nikita , Amsterdam Samuel , Lamson Melissa , Matyjaszewski Krzysztof , Bernhard Stefan , Kowalewski Tomasz
Published: June 2018

Production of sustainable fuels, such as hydrogen, is currently limited by expensive metal catalysts, and while precious‐metal‐free alternatives have been developed, price to performance is still not sufficient for practical usage. Herein, multiple activated carbons (ACs) were investigated as water‐reducing catalysts (WRCs) in photo‐driven hydrogen evolution with an Ir light harvester. Features necessary for AC catalytic activity were probed using model catalysts of various polyacrylonitrile (PAN) derived carbons, with different N content, graphitic domain size, and pore structure. N content and microporosity were found to be determining features of activity in PAN‐based carbons. The ACs initially tested as WRCs were further characterized, revealing a dependence on N content and surface area consistent with PAN‐based carbons. These results are encouraging for the use of ACs as WRCs and point to possible improvements to catalytic activity by increasing N content and microporosity.