bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Antioxidant Capacity and Enzyme Inhibitory Effect of Extracts from Prunus avium Leaves
Authors: UYSAL Sengul
Published: December 2020

Aim of study: This study aimed to investigate the antioxidant capacity and enzyme inhibitory effect of different solvent extracts obtained from Prunus avium leaves.

Material and methods: The antioxidant capacity were evaluated using in vitro assays including DPPH, ABTS, CUPRAC, FRAP, phosphomolybdenum and metal chelating activity. Enzyme inhibitory effects were screened against AChE, BChE, α-amylase, α-glucosidase and tyrosinase enzyme. Additionally, total phenolic and flavonoid content were determined spectrophotometrically.

Main results: The water extract yielded the highest phenolic content (66.65 mgGAE/g). In antioxidant assays, water extract exhibited strong antioxidant capacity (with exception of metal chelating activity). Methanol extract showed the highest enzyme inhibitory effect compared to other extracts.

Highlights: This study proved that P. avium leaves have the potential for the development of new phytopharmaceuticals or food additives.
Frameworks for Health Policy Agenda Setting in Low- and Middle-Income Countries: Protocol for A Scoping Review v1
Authors: Danforth Kristen , Namara Rebecca , Lane Jeff , Watkins David
Published: December 2020

The proposed scoping review will systematically identify and map the growing number of theoretical frameworks available to guide researchers in leveraging evidence to build political priority and inform agenda-setting for health policy and describe the identified frameworks' relevance and applicability to low- and middle-income country settings.
Ortaokul Yedinci Sınıf Öğrencilerinin Fen Bilimleri Dersi Öz Yeterlik Düzeylerinin Belirlenmesi
Authors: VARİNLİOĞLU Serdar , BEKTAS Oktay
Published: December 2020

Bu çalışmanın amacı, yedinci sınıf öğrencilerinin öz yeterlik düzeylerini belirlemektir. Araştırmada, nicel araştırma yönteminin özelliklerine uygun olarak, "tarama deseni" kullanılmıştır. Araştırmanın örneklemini Kayseri'nin Melikgazi ilçesinde bir devlet okulundan 337 öğrenci oluşturmaktadır. Çalışmada “Fen Bilimleri Dersi Öz yeterlik Ölçeği (FBÖÖ)” kullanılmıştır. FBÖÖ’nün geçerlik ve güvenirlik çalışmaları yapılmıştır. Verilerin analizinde MANOVA ve MANCOVA kullanılmıştır. Çalışmanın sonucunda yedinci sınıf öğrencilerinin fen bilimleri öz yeterlik düzeyi “yüksek” çıkmıştır. Üç faktör bağlamında kızlar ve erkekler arasında istatistiksel olarak anlamlı bir fark bulunmuştur. “Fen bilimlerine güven” faktörü kontrol altındayken kızlar ve erkeklerin arasında her iki bağımlı değişken (“fen bilimlerinde zorluklarla başa çıkabilme” faktörü ve “fen bilimleri performansına güven” faktörü) açısından istatistiksel olarak anlamlı fark yoktur. Sonuçlara dayanarak, sonuç ve tartışma ayrıntılı olarak yapılmıştır. Son olarak, öneriler sunulmuştur.
Estudo preliminar teórico de filtro compressor de pulso totalmente fotônico
Authors: Gonçalves André Paim , Richter Renan Miranda , Ivo Felipe Streitenberger , Santos Alessandro Roberto , Carreira Robson Ribeiro , Coutinho Olympio Lucchini
Published: December 2020

Este artigo propôs um estudo breve e teórico para verificar a possibilidade de uso de laços dispersivos com a técnica de auto homodinagem óptica para realizar compressão de pulso linearmente modulado em frequência de radares (linear frequency modulated –LFM). O dispositivo proposto para estudo pretendeu superar as limitações dos dispositivos equivalentes implementados pela eletrônica tal como o filtro baseado em propagação de ondas acústicas de superfície. Essas restrições foram em relação à largura de banda de radiofrequência, frequência da portadora do sinal radar e largura de pulso. Foi feita uma modelagem numérica do dispositivo proposto. Os resultados numéricos indicaram a possibilidade de emprego do compressor de pulso fotônico em radares que estão sendo desenvolvidos com grande produto da largura de banda pela largura do pulso (time bandwidth – TBW).
Microwave photonic radar warning receiver: airborne antenna over fiber optic
Authors: Kiohara Acyoli Bastos Paulo Henrique , Streitenberger Ivo Felipe , Lucchini Coutinho Olympio
Published: December 2020

Electronic warfare had great importance mainly in the Second World War. Radar was one of the greatest inventions in the area at that time, reinventing the way war was viewed until then. Nowadays, modern combat aircraft has sophisticated warfare systems. One of them is known as radar warning receiver (RWR), responsible for alerting pilots to possible radar detection and guiding the direction in which it is being radiated. Technological innovations allowed the interaction of the microwave and optoelectronics area, leading to an area known as microwave photonics (MWP). This article presents a photonic link to replace the copper cables used by RWR systems, applying photonic technology in order to improve performance and benefit from the intrinsic characteristics that optical fiber offers to the system, offering a totally passive remote system, in which only one phase modulator is connected to the RWR antenna. The results obtained for a totally photonic link by experiment were satisfactory. As expected, a gain above the unit was obtained. However, the observed noise figure was higher than expected, which ended up resulting in a lower signal noise ratio.
Effect of Artificial Night Lighting on the Growth of Loose Head Lettuce in Hydroponic System
Authors: Chua H.S. , Lai Siew Wei , Paramasivam Sivajothi , Goh T.T. , Chen Gee Chia
Published: December 2020

Supplemental LEDs lighting technology has been used as the promising lighting source in hydroponic cultures for sustainable production in urban agriculture. It could be the solution to address the growing concern about food safety, environmental impacts, bad weather, and efficient energy usage in agricultural production. In this study, the response of loose head lettuce toward the irradiance of the supplemental red-blue LED light with different power (Watt [W]) was investigated by comparing the treated lettuce with the lettuce cultured under only natural light. The lettuce plants were treated with red LED (640-660 nm) + blue LED (440-450 nm). The power output of the LEDs was specified to 3, 6, 9, 15, and 20 W. The lettuce plants were hydroponically cultured with 8 h red-blue LEDs light exposure (from 12 to 8 am) and 16 h without the red-blue LEDs light exposure (from 8 pm to 12 am) at average air temperatures of 31/28 ºC (day/night) for 50 days (7 weeks). On the harvesting day, the average shoot heights of the lettuce that was treated with 3, 6, 9, 15, 20 LEDs and natural light were 25.00, 24.75, 20.75, 19.88, 17.63, and 12.63 cm, respectively. The lettuce that was exposed to the 3 W LEDs had the highest shoot height compared to those that were exposed to LEDs with other power outputs. The average fresh weights of the lettuce that was treated with 3, 6, 9, 15, 20 W LEDs and natural light were 27.25, 24.75, 21.25, 19.88, 18.38, and 15.75 g, respectively. The results showed that the fresh weight of the lettuce that was irradiated with 3 W LED light was significantly higher compared to the lettuce that was exposed to LEDs with other power outputs. Hence, it can be concluded that supplementary LEDs lighting technology can be used as an alternative lighting source to improve the growth of lettuce in hydroponic systems. Moreover, the use of 3 W LEDs in hydroponic systems could yield a higher shoot weight and fresh weight.
Rapid Manipulation of Extracellular Vesicles using Dielectrophoretic Mechanism
Authors: Jamaludin Nur Mas Ayu , Abdul Rahim Muhammad Khairulanwar , Hamzah Azrul Azlan , Abu Nadiah , Buyong Muhamad Ramdzan
Published: December 2020

Extracellular vesicles (EVs) are small entities that are released by most cell types. EVs are important form of intercellular communication and a rich source of biomarkers for a wide variety of diseases. Many methods for EVs isolation have been utilized, however, most of them have significant drawbacks including lengthy processing time, high cost, shortfalls in selectivity and surface marker dependency. In consideration of these issues, this paper discussed on the dielectrophoresis (DEP) microelectrode method designed to rapidly isolate EVs from its medium. The advantage of this DEP microelectrode is the capability of isolating EVs using a droplet of 1 μL placed onto the microelectrode within 30 s and 20 V peak-to-peak (Vp-p) of alternating current (AC). The method used in the characterization of sample are dynamic light scattering (DLS) and transmission electron microscopy (TEM); both prove the heterogeneity of EVs’ population and the EVs appear to be spherical with size ranging from 40 to 200 nm. The experimental results from this preliminary experiment show that the DEP microelectrode was able to manipulate EVs as evidenced by the negative dielectrophoresis (NDEP) fluorescent images. Further investigation of grid analysis conducted shows the consistency of the theory and the results presented. Corrected Total Cell Fluorescence (CTCF) values from the grid analysis concluded that the EVs were manipulated to the center of region of interest, (ROI). Therefore, this DEP technique suggests a rapid strategy for EVs isolation from its medium in small quantity while maintaining accuracy and cost-effectivity.
Mechanical Impact in Disk Mill for Producing Controlled Rice Husk Particle Size by Changing Impactor Shapes and Disk Rotation Speeds
Authors: Nandiyanto Asep Bayu Dani , Ragadhita Risti , Sukmafitri Ajeng , Bilad Muhammad Roil , Aziz Muhammad , Yunas Jumril
Published: December 2020

The purpose of this study was to evaluate regulation of mechanical impact (i.e. impactor sizes and shapes) on triangle, cylinder, and cube as well as disk rotation speed (from 600 to 1500 rpm) in disk mill for controlling size-reduction process. As a model of size-reduced material, rice husk was selected. The study was done by evaluating the final milling product size, which was completed by the measurement of energy impact during the milling process. Experimental results showed that the product size was controllable in the range of between 50 and 1000 μm. The impactor sizes and shapes influenced the contact diameter and area of impactor for making more materials being collided, whereas disk rotation speed led to giving more collision number (between rice husk and impactor) and increasing impact from the collision (due to less time contact during collision). This study provides an important information, which can be further generalized in the use of milling process as a tool for materials size-reduction and mechanochemical process.
Electrochemical Properties of Natural Sensitizer from Garcinia mangostana and Archidendron pauciflorum Pericarps for Dye-Sensitized Solar Cell (DSSC) Application
Authors: Ismail Mashasriyah , Ahmad Ludin Norasikin , Hamid Norul Hisham , Al-Alwani Mahmoud A.M. , Muti Muhamed Norani , Sepeai Suhaila , Ibrahim Mohd Adib , Mat Teridi Mohd Asri
Published: December 2020

Dye-sensitized solar cells (DSSC) create imitation photosynthesis by using chemical reactions to produce electricity from sunlight. DSSC has been pursued in numerous studies due to its capability to achieve efficiencies of up to 15% with artificial photosensitizer in diffuse light. However, artificial photosensitizers present a limitation because of the complex processing of metal compound. Therefore, various types of sensitizers were developed and synthesized to surpass the artificial sensitizer performances such as natural sensitizers from bio-based materials including plants, due to simple processing techniques and low environmental impact. Thus, this study examines the potential and properties of natural sensitizers from the waste of bio-based materials from Garcinia mangostana (mangosteen fruit) and Archidendron pauciflorum (jering fruit). Both fruits pericarps have dark color pigments as dark purple and dark brown, respectively, which promise a good absorption and has potential to be used as sensitizer for DSSC. Each pericarps dye extracted using cold extraction method in methanol solvent. Electrochemical properties and photovoltaic properties of the natural photosensitizers were studied. The highest peaks of photoluminescence spectra of mangosteen and jering sensitizers were at 490 and 670 nm, respectively, due to their different types of dye pigment extracted. We also obtained the absorption spectra for both mangosteen and jering sensitizers at 380-500 and 400-600 nm, respectively, in blue shift behavior. The redox reaction was also studied using cyclic voltammetry and identify their energy levels. The DSSC device with mangosteen sensitizer achieved an efficiency of 0.38% with 35.43% (IPCE at 337 nm) and 37.75 Ω (Rs), whereas that with jering sensitizer has efficiency of 0.07% with 25.31% (IPCE at 337 nm) and 490.70 Ω (Rs). Performance studies for both photosensitizers were weak due to their HOMO-LUMO levels, but the results show that both natural dyes can be potentially applied as photosensitizer in DSSC.
Effect of Chenodeoxycholic Acid on the Performance of Dye-sensitized Solar Cells utilizing Pinang Palm (Areca catechu) Dye
Authors: Najm Asmaa Soheil , A. Ludin Norasikin , Hamid Norul Hisham , Ibrahim Mohd Adib , Mat Teridi Mohd Asri , Sopian Kamaruzzaman , Moria Hazim , Holi Araa Mebdir , AL-Zahrani Asla A. , Naeem Hasanain Salah
Published: December 2020

This study examined and described the optical and photovoltaic (PV) characterizations of the Fruit Areca catechu (pinang) as a new type of organic sensitizer. Recent reports stated that including chenodeoxycholic acid (CDCA) in the dye improves the performance of dye-sensitized solar cells (DSSCs). The effectiveness of PV dye was investigated by applying it in a DSSC. The absorption spectra indicated that natural dyes with CDCA has an excellent stabilizing ability. The Fourier-transform infrared spectra indicated the existence of carboxylic and hydroxyl functional groups in the naturally extracted dye. These functional groups were responsible for the rapid electron transfer and strong electronic linkages of interactions within the TiO2 surface. In this study, photoluminescence spectra analysis showed that by narrowing the bandgap, incorporating CDCA as a co-adsorbent in natural dye could generate a significant photocurrent. The overall power conversion efficiency was enhanced by 4.6%. Moreover, the cell efficiency reached up to 0.076% after adding 1.5 mM of CDCA without optimizing the sensitization time. Results demonstrated that the present study contributes toward the improvement of DSSC through efficient electron injection.
Effect of Shock Wave on Constant Load Behaviour of Pb-Free/Cnt Solder Joint
Authors: Ismail Norliza , Jalar Azman , Wan Yusoff Wan Yusmawati , Safee Nur Shafiqa , Ismail Ariffin
Published: December 2020

The constant load behaviour of SAC305 solder joint with addition of carbon nanotube (CNT), exposed to shock wave condition was investigated. Formulated SAC305-CNT solder pastes with 0.04 wt. % CNT were manually printed to the printed circuit board (PCB) with copper surface finish to form solder joint. The solder joint was exposed to the shock wave condition via open field blast air test using Trinitrotoluene (TNT) explosive. Nanoindentation approach was used to determine the constant load behavior of the SAC305-CNT solder joint under shock wave condition. The results showed that addition of CNT reduced the indentation depth of SAC305 solder joint at 10 mN peak load for blast test sample and control sample. Indentation depth displacement of SAC305-CNT solder joint for blast test sample and control sample were reduced about ~ 42 and ~56%, respectively, if compared to the SAC305 solder joint for blast test sample and control sample. SAC305-CNT solder joint was experienced minimal changes of stress exponent when exposed to the shock wave. The existence of CNT in the solder joint slows down the depth displacement due to constant load.
Mechanical Strength Enhancement of Porous Nanocrystalline-Silicon (pnc-Si) Membrane via Titanium-oxide (Ti-O) Coating
Authors: Latif Rhonira , Jaafar Muhammad Fahmi , Aziz Mohd Faizal , Majlis Burhanuddin Yeop
Published: December 2020

Porous nanocrystalline silicon (pnc-Si) membrane is mainly studied as a blood filtration membrane, mimicking the glomerulus filtration membrane of a human kidney. However, the pnc-Si material itself is not hemocompatible and enormous membrane area to thickness ratio makes the membrane to be easily fractured. Silicon surface modification via titanium-oxide (Ti-O) thin film layer deposition has been proven to be hemocompatible and the presence of Ti-O layer has been numerically studied to give higher membrane flexural strength. In this work, square pnc-Si membranes of 2 mm × 2 mm × 20 nm size have been fabricated with and without Ti-O layer. Point loading-unloading nanoindentation method has been performed and the membranes’ displacement behaviour subjected to point loads is studied. The pnc-Si membranes with Ti-O layer were found to attain higher fracture strength, membrane bending stiffness and average hardness with the increase of ~20, ~11 and ~24%, respectively, compared to bare pnc-Si membranes. The mechanical strength of a free-standing pnc-Si membrane is improved by depositing a Ti-O thin film layer on the membrane structure.
Influence of Multilayer Al-Doped ZnO Thin Film on Photocatalytic Degradation of Methyl Blue
Authors: Liszulfah Roza Liszulfah Roza , Vivi Fauzia Vivi Fauzia , Abd. Rahman Mohd. Yusri
Published: December 2020

The present work is focused on the photocatalytic activities of Al-doped ZnO sample deposited with different layers on glass substrate. The Al-doped ZnO sample was prepared via simple and cost effectiveness chemical precipitation method with addition of 5 wt. % of Aluminum chloride as dopant. All materials were dissolved in mixture of 45 mL ethylene glycol and 15 mL deionized water while the growth process was carried out at temperature 200 °C for 30 min assisted with stirring process at 550 rpm using hotplate. The precipitated of as prepared sample were deposited with different layers on glass substrate using spin coating process. The samples were characterized by UV-Vis spectrophotometer, Raman spectroscopy, and photoluminescence to investigate the optical properties and crystal structure of ZnO sample. In particular, according to UV-Vis the absorption spectra of the sample significantly increase as the number of layers increase. Meanwhile, Raman and photoluminescence analysis indicate that the sample contains lots of structural defect as a result of the incorporation of ion Al into ZnO lattice. The photocatalytic activity of Al-doped ZnO thin film with different layers was evaluated in degradation of methyl blue solution under UV light illumination. The best photocatalytic activity was observed from 6 layers of Al-doped ZnO thin film within 45 min of exposure to UV light illumination. This study may open a versatile route to achieving high efficiency of photocatalytic activity of ZnO.
Analysis of Mg(OH)2 Deposition for Magnesium Air Fuel Cell (MAFC) by Saline Water
Authors: Basri Sahriah , Hazri Nurul Shahzira , Selladurai Shanjeva Rao , Zainoodin A.M. , Kamarudin S.K. , Zakaria S.U. , Hashim A.R.
Published: December 2020

Magnesium air fuel cell (MAFC) systems are eco-friendly fuel cells that use electrolytes of saltwater and oxygen from the air to produce power. However, MAFC cells face a critical problem, which is the deposition of side products on the surface of the Mg anode plate and the cathode electrode. Therefore, this study will focus on the analysis of factor on Mg(OH)2 deposition by identifying the optimal seawater, Mg alloy, and surface roughness and additives solution. Magnesium plates AZ31 are used as the anode, and air electrode as the cathode. This study also considers physical characteristics such as SEM, EDX and corrosion test while chemical characterization by performance test with difference electrolyte, anode, and roughness. Catechol-3,5-disulfonic acid disodium salt (tiron) as anti-deposition used to reduce the deposition of Mg(OH)2 on the anode and cathode surfaces and thus improve the performance of MAFC. From the performance study, the MAFC able to produce a power density of 27.54 mW/cm2 which is high compare to the MAFC without tiron. Therefore, with the active area by 110.25 cm2, the MAFC generates 2.93 W. The deposition of Mg(OH)2 reduces the active area of magnesium oxidation, thus, reduce the electricity generation. With the knowledge of optimal seawater concentration and improvement of a single fuel cell system, this study is expecting to assist the fisheries and aquaculture sector as well as the coastal communities in terms of providing a better, safer, and cheaper alternative source of electricity.
The Influence of Temperature and Electroforesis Deposition Green Inhibitor on Bipolar Plate AA5052 in Sulfuric Acid Medium
Authors: Arwati I Gusti Ayu , Majlan Edy Herianto , Loh Kee Shyuan , Teuku Husaini Teuku Husaini , Alva Sagir , Muhajirin Muhajirin , Mohd Radzuan Nabilah Afiqah
Published: December 2020

Aluminum alloy 5052 (AA5052) contains Mg (2.2-2.8.8% weight), Cu (0.1% weight), Cr (0.15% weight), Zn (0.1% weight), Si and Fe (0.45% weight) compositions. This material has been widely used as a bipolar plate in Proton exchange Membrane (PEMFC) fuel cells. This material has several advantages such as: lightness, high conductivity, good tensile strength, and flexibility. PEMFC operations produce several by-products, such as water and heat. Generally, the operation of PEMFC is around 333-353 K and the environment is acidic. In this condition the bipolar plate AA5052 will easily experience rust, thus lowering the performance of the PEMFC. In this study, 0.5 g/L Arabic Gum (AG) used as a green inhibitor and coated onto the AA5052 surface through electrophoretic deposition (EPD). The corrosion test was performed in 0.5 M H2SO4 (pH 2) solution under the simulated PEMFC condition. Scanning electron microscopy (SEM) was used to analyze the morphology, and potentiodynamic polarization to determine the corrosion rate. Result shows that AG coating can reduce 60% the corrosion rate of AA5052 after immersed in 0.5 M H2SO4 for 168 h. The effect of temperature on the inhibition efficiency reached 14.4% under the same condition. AG can be used as a green inhibitor to reduce the corrosion rate of AA5052 bipolar plate.
UKM2 Chlorella sp. Strain Electricity Performance as Bio-anode under Different Light Wavelength in a Biophotovoltaic Cell
Authors: Juhari Aisyah Nadhirah , Sharani Muhd Syazwan , Wan Daud Wan Ramli , Jafary Tahereh , Abu Bakar Mimi Hani
Published: December 2020

A biophotovoltaic cell (BPV) is an electrobiochemical system that utilises a photosynthetic microorganism for instance is algae to trap sunlight energy and convert it into electricity. In this study, a local algae strain, UKM2 Chlorella sp. was grown in a BPV under different trophic conditions and light wavelengths. Once the acclimatisation phase succeeded, and biofilm formed, power generation by UKM2 algae at the autotrophic mode in synthetic Bold’s Basal media (BBM) under white, blue and red lights were tested. Polarisation and power curves were generated at these different conditions to study the bioelectrochemical performance of the system. Later, the condition switched to algal mixotrophic nutritional mode, with palm oil mill effluent (POME) as substrate. Maximum power generation obtained when using UKM2 in BBM under red light where a power density of 1.19 ± 0.16 W/m3 was obtained at 25.74 ± 3.89 A/m3 current density, while the open circuit voltage OCV reached 226.08 ± 8.71 mV. UKM2 in POME under blue light recorded maximum power density of 0.85 ± 0.18 W/m3 at current density of 16.75 ± 3.54 A/m3, while the OCV reached 214.05 ± 23.82 mV. Chemical oxygen demand (COD) removal reached an efficiency of 35.93%, indicating the ability of wastewater treatment and electricity generation in BPV at the same time.
Diagnosis of sleepiness, fatigue and depression in patients with myasthenia gravis
Authors: Kreis O. A. , Alekseeva T. M. , Gavrilov Yu. V. , Valko P. O. , Valko Yu.
Published: December 2020

Introduction. Examination of excessive daytime sleepiness, fatigue and depression in patients with myasthenia gravis is important for differential diagnosis of other disorders, and adds to a comprehensive clinical assessment.

Objective. The aim is a comprehensive assessment of sleepiness, fatigue and depression and evaluation of the impact of autoimmune comorbidity on these symptoms in myasthenia gravis patients, using newly validated Russian versions of international questionnaires. The present article aims at familiarizing a wider Russian-speaking audience of specialists in the field of neuromuscular disease and sleep medicine with the main findings of our previously published work.

Materials and methods. The study included 73 patients with MG and 230 control subjects. For sleepiness, fatigue and depression evaluation were used: Fatigue Severity Scale (FSS), Fatigue Impact Scale (FIS) (cognitive / physical / psychosocial subscales), Epworth Sleepiness Scale (ESS), Beck Depression Inventory (BDI) (cognitive-affective and somatic domains), Spielberger–Khanin State Trait Anxiety Inventory (STAI).

Results. The Fatigue Severity Scale and Fatigue Impact Scale showed good psychometric properties and can be used to identify distinct aspects of fatigue in patients with myasthenia gravis. The studied patient cohort revealed clinically significant fatigue (69.9 %), excessive daytime sleepiness (15.1 %), moderate to severe depression (20.5 %), a high level of personal (64.4 %) and situational anxiety (27.4 %). Among 13 patients with myasthenia gravis and additional autoimmune comorbidity, there were no significant differences in the severity of sleepiness, fatigue and depression compared with the main group.

Conclusion. The use of self-reported scale of sleepiness, fatigue and depression combined with careful clinical-neurological characterization adds to a more comprehensive view of the patient. The identification of sleepiness, fatigue and depression can guide therapeutic decisions and contributes to a better patient care. The presence of concomitant autoimmune pathology in patients with myasthenia gravis does not seem to increase the severity of sleepiness, fatigue and depression.
MANAGEMENT OF INVESTMENT VALUE IN THE INTEGRATED DEVELOPMENT OF THE TERRITORY
Authors: Ishamyatova I. H. , Ashirova T. G. , Abdrazakova I. I.
Published: December 2020

Currently, there is an acute problem of implementing investment projects for integrated development of territories. Important indicators of the effectiveness of integrated development projects for state authorities and investors (developers) are investment value and investment value management efficiency. The purpose of this work is to develop an algorithm that allows you to calculate the true investment value and competently manage projects for the integrated development of the territory for the purposes of housing construction. The object of the research is the investment value of the land plot for the integrated development of territories for housing construction purposes. The subject of the research is the mechanisms of managing the investment value of the integrated development of territories for housing construction. Baseline data are studies of various authors to determine the effectiveness of investment value management. Conducted research in this area allowed the authors to determine the main stages of managing the investment value of the integrated development of the territories and the factors that make up the investment value. The main result of the research is a compiled algorithm of an economic-mathematical model for managing the investment value of a land plot in integrated land use projects for housing construction. This algorithm consists of 10 stages. In the first two stages, information is collected about the land plot. At the third and fourth stage, calculations of land, town planning balances, technical conditions, and costs are made. The fifth one calculates the possible profit, and the sixth one predicts the possible risks. Based on previous studies (stages 1-6), at stage 7, a preliminary assessment of the investment value is made. At stages 8-10, the investment cost is agreed upon, the possibility of raising budget funds is assessed, and management decisions are made. Following the steps of the algorithm, it is possible to calculate the investment value of the land plot. The practical significance of the results obtained is connected with the possibility of their use for making sound management decisions in the field of land and property relations, in particular, for solving problems related to the management of integrated development projects by territories.
Psychological Well-Being of Students in Inclusive Higher Education in Arts: The Experience of Structural Analysis
Authors: Sobkin V.S. , Lykova T.A. , Sobkina A.V.
Published: December 2020

The article focuses on the study of the features of psychological well-being in healthy students and students with disabilities. It was assumed that self-assessment of psychological well-being in students with disabilities and healthy students differs in structure and content. The study involved 167 students, 98 with normative development and 67 with various types of disabilities (hearing, vision impairments etc.).The survey was conducted on the basis of Russian State Specialized Academy of Arts (RSSAA) with students of all faculties (theater, music, fine arts).We used the following techniques: the life satisfaction scale and the subjective happiness scale. It is shown that the perception of psychological well-being among students of the inclusive university is more differentiated. The assessment of psychological well-being is based on three parameters: ‘life satisfaction in general’; ‘life optimism, self- realization — satisfaction with the past’; ‘assessing oneself as happier than one’s peers’. Self-assessment of psychological well-being is based on the time dynamics of life’s journey: a retrospective view of one’s life and its perception from the point of view of future prospects.
Interpersonal Sensitivity in the Period of Self-Isolation and Its Role in the Choice of Social Distancing Measures
Authors: Polskaya N.A. , Razvaliaeva A.Y.
Published: December 2020

The present study was called forth by the relevant issue of COVID-19 pandemic. We emphasize that it emerged as a traumatic situation for many people, whereas measures against its spread further exacerbate psychological distress. In the current study we focused on interpersonal sensitivity in the clinical sense, as a heightened vulnerability to emotions and behaviors of the others linked to expectations of critique and rejection. The study examined the relationships between interpersonal sensitivity and a) protective measures against COVID-19; b) affiliation motivation, loneliness and current emotional state. The relationships were assessed employing correlation, regression and mediation analysis. The sample included 496 people (85,5% women and 14,5% men), aged 14—59 (M=20,42; SD=6,2).We used a survey including questions on adherence to social distancing recommendations and use of protective measures, the Russian versions of PANAS, UCLA Loneliness Scale, Mehrabian’s Affiliative Tendency and Sensitivity to Rejection Scales and Interpersonal Sensitivity Measure. The results show that interpersonal sensitivity increased in youth, positively correlated with negative affect, loneliness and fear of rejection, and negatively correlated with affiliation motivation, positive affect and self-reported psychological and physical state. Interpersonal sensitivity positively and affiliation motivation negatively predicted the choice of two protective measures: going out less and limiting contacts. Affiliation motivation mediated the relationship between interpersonal sensitivity and going out less.
EXPECTATIVAS E MUDANÇAS DE COMPORTAMENTO DE PAIS E ADOLESCENTES COM SÍNDROME METABÓLICA PARTICIPANTES DE UM PROJETO INTERDISCIPLINAR PARA PROMOÇÃO DA SAÚDE
Authors: Silva Tânia Maria Gomes da , Garcia Lucas França , Oliveira Daniel Vicentini de , Anversa Ana Luiza Barbosa , Santos Natália Quevedo dos , Branco Bráulio Henrique Magnani
Published: December 2020

Este estudo buscou analisar como um programa de intervenções interdisciplinares, realizado em uma instituição de ensino superior (IES), contribuiu para a promoção da saúde de adolescentes com síndrome metabólica (SM). Em um laboratório sediado na IES, foi realizada uma pesquisa de abordagem qualitativa, de natureza descritiva e exploratória, por meio de entrevistas semiestruturadas com 16 adolescentes, de ambos os sexos, com idades entre 16 e 18 anos e seus respectivos pais/responsáveis legais. A coleta de dados transcorreu de novembro a dezembro/2018. A interpretação seguiu a análise de conteúdo de Bardin, sendo elencadas três categorias a priori: expectativas quanto à intervenção, percepção da saúde antes e após a participação no programa, mudanças percebidas no comportamento a partir das ações desenvolvidas; barreiras e motivações para o engajamento dos adolescentes no programa. Os resultados evidenciam ter havido grande expectativa quanto à perda de peso, tanto por parte dos participantes diretos quanto dos pais ou responsáveis; que as ações e discussões propostas ampliaram o conceito de saúde, sendo os transtornos de deslocamento e a mudança de hábitos descritos como as maiores dificuldades enfrentadas pelos jovens para a participação no programa. Foi possível perceber, ainda, que houve boa compreensão quanto aos impactos negativos da SM na saúde e na qualidade de vida, fator que levou a intenção de comprometimento futuro com a adoção de hábitos mais saudáveis. Fundamentado nos aspectos elencados, conclui-se que o programa interdisciplinar para a promoção da saúde em adolescentes com SM proporcionou a literacia em saúde para os adolescentes investigados.
PERCEPÇÃO DE RISCO DAS MULHERES DE CANOAS/RS NO SEU TRAJETO DIÁRIO
Authors: Machado Rafaela Vieira , Campos Camila Bolzan de
Published: December 2020

As mulheres enfrentam o desafio de se locomover com segurança em seus trajetos diários. Assédios físicos e psicológicos estão presentes em suas rotinas. As evidências perigosas que a cidade pode acarretar a estes trajetos no âmbito urbano traz à tona a relevância de descrever este possível impacto na mobilidade de mulheres. Tendo em vista este panorama, o presente estudo tem como objetivo analisar como a violência influencia os padrões de mobilidades das mulheres do munícipio de Canoas/RS. Trata-se de uma pesquisa que utiliza métodos mistos em seu delineamento, em que 402 mulheres moradoras do município de Canoas/RS participaram através de um questionário enviado via redes sociais. Através desta pesquisa foi possível afirmar que as mulheres têm suas rotinas alteradas em função da violência nos centros urbanos.
DIREITO À CIDADE E AO DIREITO DA FAVELA: RELAÇÕES MÚTUAS DE FORMAÇÃO E ADAPTAÇÃO
Authors: Vigário Sophia da Silva , Sozinho Juliana Yumi  Fernandes , Pinto Phylippe Pimentel , Souza Helane Aglaê Santos de , Santos Ana Flávia Brito dos , Dias Daniella Maria  dos Santos
Published: December 2020

O presente trabalho buscou estabelecer a relação entre a ausência de efetivação do Direito à Cidade por parte do Estado e o surgimento e expansão do Direito da Favela e seus mecanismos de regulamentação. Para tanto, buscou-se uma definição conceitual de Direito à Cidade e Direito da Favela, com base na literatura existente, para chegar à relação entre ambos. Visando uma demonstração prática dessa relação, utilizou-se um estudo do processo de implementação do Direito de Laje no Direito brasileiro. A partir disso, conclui-se que com a ausência dos mecanismos garantidores estatais, regularizados pelos direitos de propriedade e permitam o acesso do direito à cidade a todos os cidadãos, a favela cria instituições próprias; e, a partir desse surgimento, as políticas estatais de regularização não podem ignorá-las, sob o risco de ineficácia e ineficiência. A metodologia utilizada baseia-se no método dedutivo e em pesquisa bibliográfica e documental.
REPRESENTAÇÕES SOBRE MARGARET THATCHER NA REVISTA VEJA (1979 - 1983)
Authors: Pintarelli Eduardo , Brandão Leonardo
Published: December 2020

Analisa-se a representação da primeira ministra do Reino Unido, Margareth Thatcher, produzida pela revista Veja. Margareth Thatcher é apontada pela Historiografia Contemporânea como uma das primeiras governantes a implementar o conjunto de políticas econômicas denominado neoliberalismo. Desta forma visa-se abordar o modo como a revista Veja noticiou, comunicou, apresentou um governo neoliberal ao seu público brasileiro em suas representações da primeira ministra inglesa. Em se tratando de uma pesquisa em periódicos, é analisado um conjunto de diferentes perspectivas de representação, todas atreladas a uma mesma personagem histórica.
Molecular Insight of the Possible Inhibition Mechanism of Therapeutic Cephalosporin Derivatives against Human Glutathione Reductase Enzyme
Authors: KARAMAN Muhammet
Published: December 2020

Glutathione reductase is a key enzyme for glutathione metabolism. Inhibition of the enzyme activity related to various health problems. Therefore, determination of inhibitors of the enzyme and its possible inhibition mechanism are quite important. Some cephalosporins have exhibited potent inhibitory effect against human glutathione reductase (hGR). In order to understand the inhibition mechanism of the cephalosporins, we carried out molecular docking studies with Glide docking and Induced-fit Docking methods. Binding sites of hGR were predicted and the best suitable binding site of the drugs was identified with the Glide docking method. The binding affinity of the drugs was calculated with the induced-fit docking method. The best binding site of the drugs was detected as a part of the catalytic active site for Cefoperazone, Cefodizime, and Ceftazidime, dimerization site for Cefotaxime, Ceftriaxone, and Cefuroxime, and aromate binding site for Ceftizoxime. The Binding affinity of the Cefoperazone was calculated as -10.643 kcal/mol. The results have indicated that hGR enzyme would be inhibited with different mechanisms because of its several druggable sites. These findings would be helpful for designing new inhibitors for hGR enzyme and understanding of potential inhibition mechanism of its other known inhibitors.
Comparison of Type-2 Fuzzy Inference Method and Deep Neural Networks for Mass Detection from Breast Ultrasonography Images
Authors: UZUNHİSARCIKLI Esma , GÖREKE Volkan , SARI Vekil
Published: December 2020

In this study, mass detection from breast ultrasonography images was realized using deep neural networks. Dataset is a collection of publicly available ultrasonography images which were classified by their biopsy results. A total of 153 breast ultrasonography images that contain 89 malign and 64 benign tumours were used. Image augmentation and deep neural network software was developed using Python 3,5 environment on Visual Studio Community 2017 IDE. A hybrid method including Keras ImageDataGenerator Class and image preprocessing techniques was introduced. Twenty images from both classes were randomly split from the dataset for testing after the network was designed. The network had a success rate of 100% at an epoch value of 70. The result of this study was compared with the result of another study that implemented type-2 fuzzy inference system with a success rate of 99,34%.

As a conclusion, it can be expressed that the deep neural networks are more successful than fuzzy inference systems in tumour detection from breast ultrasonography images. Therefore, it can be more convenient to use deep neural network technology in computer aided detection systems for mass detection from breast ultrasonography images.
Memantine activates LKB1-AMPK pathway in breast carcinoma cells
Authors: BALİ Elif Burcu
Published: December 2020

Drug repositioning that is a screening of presently approved drugs for already unknown indications is therapeutically necessary and influential for drug discovery. In this study, it was aimed to research whether memantine as a repositioned drug can activate the LKB1-AMPK pathway in breast carcinoma cells by triggering tumor suppressor genes LKB1, AMPK, its downstream targets 40S ribosomal S6 kinases (S6K1 and S6K2), and eukaryotic initiation factor 4E-binding protein 4E-BP1. It was also evaluated its apoptotic effect by detecting the gene expressions of Caspase 7 and NOXA. Thus, MCF-7 cells were treated with 250 µM memantine for 48 h, and its cytotoxic effect was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. AMPKα1, AMPKα2, S6K1, S6K2, 4E-BP1, Caspase 7 and NOXA gene expression levels were measured by quantitative real-time polymerase chain reaction. The results clearly revealed that memantine inhibited MCF-7 cell proliferation and activated the LKB1-AMPK pathway by reducing S6K1, S6K2, and 4EBP1 gene expressions. Memantine also augmented the gene expressions of Caspase 7 and NOXA. The findings reveal a molecular mechanism for the first time that may contribute to the anti-cancer effect of memantine to prevent or treat breast cancer. But further research should be performed to better understand its anti-cancer action.
Stabilitas Emulsi dan Sensori Mayones Campuran Minyak Abdomen Ikan Patin dan Minyak Sawit Merah dengan Penambahan HPMC SS12 Sebagai Penstabil
Authors: Ayu Dewi Fortuna , Lumban Gaol Tiara Septiani , Diharmi Andarini
Published: December 2020

The purpose of this research was to determine the effect of HPMC SS12 concentration on emulsion stability and sensory quality of mayonnaise made from patin and red palm mixture oil.  This study used a Completely Randomized Design (CRD) with five treatments and three replications. The treatments performed were P0 (without addition of HPMC SS12), P1 (addition of 2% HPMC SS12), P2 (addition of 3% HPMC SS12), P3 (addition of 4% HPMC SS12), and P4 (addition of 5% HPMC SS12).  Data were statistically analyzed using analysis of variance (ANOVA) and then continued with Duncan`s New Multiple Range Test (DNMRT) at 5% level.  Results of the research showed that the addition of HPMC SS12 significantly affected viscosity, degree of acidity (pH), emulsion stability, and sensory test of the mayonnaise thickness, but did not significantly affect moisture content, sensory test of the mayonnaise color and flavour.  The best treatment was P3 (addition of 4% HPMC SS12) which had 4.53 degree of acidity (pH), 16109.33 cP viscosity, 29.78% moisture content, 72.33% emulsion stability on the 1st day, and 71.33% emulsion stability on the 15th day.  Result of the descriptive test on the mayonnaise were orange somewhat yellow color, slightly rancid in aroma, and thick texture.  Result of the hedonic test on overall of the mayonnaise was rather preferred by panelists.
Analisis Kualitas Minyak Nilam dan Faktor yang Mempengaruhi Keputusan Petani Dalam Memilih Ketel Penyulingnya
Authors: Mukhtar Tomi , Widayat Heru Prono , Abubakar Yusya
Published: December 2020

Aceh Province (as one of the major producer in Indonesia) produces about 423 tons of patchouli oil yearly, harvested from about 2.041ha patchouli farm. One of problems faced by patchouli farmer is related to post-harvest handling process, especially during distillation. Many farmers still use simple distillation equipment made from used drums, so that the quality of the oil is relatively low. In the meantime, equipment made from better materials (such as stainless steel) is already available commercially, but farmer has not yet willing to adopt the technology. The aims of this study are to determine the percentage of farmers who still use the distillation unit made from used drum, analyze the yield and quality of patchouli oil at the farm level, and analyze the factors that influence the farmer decision in choosing the type of distillation unit. Respondents in this study came from three sub-districts of patchouli producers in South Aceh District. Data was collected by means of interviews, distribution of questionnaires, and observation. Patchouli oil samples were taken from farmers' patchouli distillation unit to be analyzed. The results showed that the majority of farmers still used distillation unit made from used drums (79%), while those who use stainless steel distillation unit is very small (21%). The laboratory analysis (by GC-MS) showed that the quality of patchouli oil from stainless steel distillation unit is better than patchouli oil from used-drum distillation unit. The factors that influence farmer’s decision in choosing type of distillation units are the initial investment costs and operational costs of distillation unit. Many farmers find it difficult to get enough initial capital to buy the stainless steel unit, therefore the majority of farmers choose to use used-drum distillation unit (which is cheaper) instead of stainless steel unit.
Cooper-Norcross Tercih Envanteri Türkçe Uyarlaması : Bir Geçerlik ve Güvenirlik Çalışması
Authors: ÖZER Ömer , YALÇIN İlhan
Published: December 2020

Bu çalışmanın amacı Cooper-Norcross Tercih Envanterinin Türkçeye uyarlanmasıdır. Cooper-Norcross Tercih Envanteri bireylerin psikolojik yardım sürecindeki rollere ilişkin tercihlerini değerlendiren bir özbildirim aracıdır. Araştırmanın çalışma grubu 536 (kadın =310, erkek = 226) üniversite öğrencisinden oluşmaktadır. Ölçme aracının uyarlama sürecinde orijinal form dikkate alınarak çeviri ve tekrar çeviri çalışması yapılmış, uzman görüşlerine dayanarak düzenlenen form ile dört farklı üniversiteden veri toplanmıştır. Verilerin analizi kapsamında doğrulayıcı faktör analizi kullanılmıştır. Analiz sonuçlarına göre ölçme aracının orijinal faktör yapısının doğrulandığı görülmüştür ( X²/ sd (543.398 / 129)=3.59, RMSEA (0.071; 0.08) .069, CFI .912, IFI .912, GFI .906, SRMR .071 ). Ölçme aracı Danışman Yönlendiriciliğine Karşı Danışan Yönlendiriciliği , Duygusal Yoğunluğa Karşı Duygusal Sınırlılık, Geçmiş Zaman Yönelimliliğe Karşı Şimdiki Zaman Yönelimlilik ve Samimi Desteğe Karşı Odaklı Yüzleştirme olarak isimlendirilen dört alt boyuttan oluşmaktadır. Alt boyutlara ilişkin Cronbach Alfa içtutarlık katsayıları .55 ile .65 arasında değişmektedir. Ölçme aracının geçerlik ve güvenilirliğinin ortaya konması amacı ile test tekrar test, alt üst %27’lik gruplar arası farkın değerlendirilmesi ve benzer ölçek geçerliği yöntemleri kullanılmıştır. Ölçme aracı toplam puan vermemekte her bir alt boyut ayrı ayrı hesaplanmaktadır. Bir alt boyutta puanın yükselmesi alt boyut isimlendirmesinde ilk ifade edilen alana ilişkin tercihin daha baskın olduğunu göstermektedir. Elde edilen bulgular Cooper- Norcross Tercih Envanteri’nin üniversite öğrencilerinin psikolojik danışma sürecine ilişkin tercihlerini değerlendirmede kullanılabilecek geçerli ve güvenilir bir ölçme aracı olduğunu göstermektedir.
Sorption and Isomerselective Properties of Binary Sorbent Based on Supramolecular 4-(3-Hydroxypropyloxy)-4'-Formylazobenzene Liquid Crystal and Partially Methylated β-Cyclodextrin
Authors: Onuchak L. A. , Tugareva D. A. , Kapralova T. S. , Kuraeva Yu. G.
Published: December 2020

The sorption and selective properties of a composite sorbent based on the supramolecular liquid crystal 4-(3-hydroxypropyloxy)-4'-formylazobenzene (HPOFAB) and partially methylated β-cyclodextrin heptakis-(2,6-di-O-methyl)-β-cyclodextrin (Me2,6-β-CD) have been studied by inverse gas chromatography. The standard thermodynamic functions of sorption on the smectic A phase of the sorbent for 29 volatile organic compounds of different classes were determined and compared with similar functions obtained on a column with “pure” HPOFAB. The reasons for the increase in the retention of all studied compounds (except for the optical isomers of butanediol-2,3) when Me2,6-β-CD (10 wt. %) added to HPOFAB are discussed. It was found that the mixed SA phase of the binary sorbent in conditions of gas-liquid chromatography has moderate values of structural selectivity and enantioselectivity to both low-polar terpene hydrocarbons and polar optical isomers (butanediols-2,3).