bluuebunny/crossref_metadata_2025 huggingface dataset:
Eri silkworm spins mechanically robust silk fibers regardless of reeling speed
Authors: Yazawa Kenjiro , Tatebayashi Yuka , Kajiura Zenta
Published: January 2022

Wild silkworms survive in environmental habitats in which temperature and humidity vary based on the weather. In contrast, domesticated silkworms live in mild environments where temperature and humidity are generally maintained at constant levels. Previous studies showed that the mechanical strengths and molecular orientation of the silk fibers reeled from domesticated silkworms are significantly influenced by the reeling speed. Here, we investigated the effects of reeling speed on the mechanical properties of eri silk fibers produced by wild silkworms, Samia cynthia ricini, which belong to the family of Saturniidae. We found that the structural, morphological and mechanical features of eri silk fibers are maintained irrespective of the reeling speed, in contrast to those of domesticated silkworm silk fibers. The obtained results are useful not only for understanding the biological basis underlying the natural formation of silk fibers but also for contributing to the design of artificial spinning systems for producing synthetic silk fibers.
The interplay of directional information provided by unpolarised and polarised light in the heading direction network of the diurnal dung beetle Kheper lamarcki
Authors: Khaldy Lana , Foster James J. , Yilmaz Ayse , Belušič Gregor , Gagnon Yakir , Tocco Claudia , Byrne Marcus J. , Dacke Marie
Published: January 2022

The sun is the most prominent source of directional information in the heading direction network of the diurnal, ball-rolling dung beetle Kheper lamarcki. If this celestial body is occluded from the beetle's field of view, the distribution of the relative weight between the directional cues that remain shifts in favour of the celestial pattern of polarised light. In this study, we continue to explore the interplay of the sun and polarisation pattern as directional cues in the heading direction network of K. lamarcki. By systematically altering the intensity and degree of the two cues, we effectively change the relative reliability as they appear to the dung beetle. The response of the beetle to these modifications allows us to closely examine how the weighting relationship of these two sources of directional information is influenced and altered in the heading direction network of the beetle. We conclude that the process by which K. lamarcki relies on directional information is very likely done based on Bayesian reasoning, where directional information conveying the highest certainty at a particular moment is afforded the greatest weight.
Η Αειφόρος Ανάπτυξη στην Αρχική Εκπαίδευση και την Επιμόρφωση των Εκπαιδευτικών Πρωτοβάθμιας Εκπαίδευσης: Μια Επισκόπηση της Διεθνούς Βιβλιογραφίας
Authors: Στάχτιαρη Αναστασία , Μουζάκης Χαράλαμπος
Published: January 2022

Η αρχική εκπαίδευση και η επιμόρφωση των εκπαιδευτικών αναγνωρίζονται ως παράγοντες ουσιώδους σημασίας για την καλλιέργεια τα γνώσεων, των ικανοτήτων, των δεξιοτήτων, των στάσεων και των αξιών που πρεσβεύει η εκπαίδευση για την αειφορία. Η παρούσα εργασία αποσκοπεί στη διερεύνηση της προβληματικής που αναπτύσσεται στη διεθνή βιβλιογραφία και αφορά τόσο στη φυσιογνωμία των προγραμμάτων αρχικής εκπαίδευσης και επιμόρφωσης των εκπαιδευτικών Πρωτοβάθμιας Εκπαίδευσης, όσο και στα πορίσματα της διεθνούς βιβλιογραφίας για τους παράγοντες που επηρεάζουν την αξιοποίηση των αρχών της αειφορίας στη διδακτική πράξη. Η βιβλιογραφική επισκόπηση αξιοποίησε εμπειρικές έρευνες που εστιάζουν στην εκπαίδευση και την επιμόρφωση εκπαιδευτικών Πρωτοβάθμιας Εκπαίδευσης, όπως αυτές εντοπίστηκαν στις βάσεις δεδομένων Science Direct, Scopus, Web of Science, ERIC και Google Scholar. Μέσω της συστηματικής αναζήτησης, αξιολόγησης και ανάλυσης της βιβλιογραφίας εντοπίστηκαν 35 εργασίες που πληρούσαν τα κριτήρια που είχαν τεθεί στη βάση των ερευνητικών ερωτημάτων. Μέσα από την ανασκόπηση των ερευνητικών εργασιών υπογραμμίζεται η σημασία της σπουδής της αειφορίας, ως συγκροτημένου επιστημονικού πεδίου και τονίζεται η ανάγκη της καλλιέργειας της ικανότητας των εκπαιδευτικών να συνενώνουν στις διδακτικές τους πρακτικές την επαγγελματική τους ειδημοσύνη με τις αρχές της αειφορίας.
Microscope-Cockpit: Python-based bespoke microscopy for bio-medical science
Authors: Phillips Mick A. , Susano Pinto David Miguel , Hall Nicholas , Mateos-Langerak Julio , Parton Richard M. , Titlow Josh , Stoychev Danail V. , Parks Thomas , Susano Pinto Tiago , Sedat John W. , Booth Martin J. , Davis Ilan , Dobbie Ian M.
Published: January 2022

We have developed “Microscope-Cockpit” (Cockpit), a highly adaptable open source user-friendly Python-based Graphical User Interface (GUI) environment for precision control of both simple and elaborate bespoke microscope systems. The user environment allows next-generation near instantaneous navigation of the entire slide landscape for efficient selection of specimens of interest and automated acquisition without the use of eyepieces. Cockpit uses “Python-Microscope” (Microscope) for high-performance coordinated control of a wide range of hardware devices using open source software. Microscope also controls complex hardware devices such as deformable mirrors for aberration correction and spatial light modulators for structured illumination via abstracted device models. We demonstrate the advantages of the Cockpit platform using several bespoke microscopes, including a simple widefield system and a complex system with adaptive optics and structured illumination. A key strength of Cockpit is its use of Python, which means that any microscope built with Cockpit is ready for future customisation by simply adding new libraries, for example machine learning algorithms to enable automated microscopy decision making while imaging.
Tax law of the EAEU States
Authors: Kozyrin Aleksandr
Published: January 2022

The textbook contains a basic amount of knowledge on the tax law of the EAEU member states. It complements the compulsory course "Tax Law", identifies common features and differences inherent in the tax legislation of the EAEU states, and also defines the directions in which the harmonization of tax and legal regulation in the integration association of Armenia, Belarus, Kazakhstan, Kyrgyzstan and Russia should be conducted.
For undergraduate and graduate students studying at law and economics faculties, graduate students and trainees of the advanced training system.
Commentary to the Federal Law "On Operational Investigative Activities"
Authors: Ovchinskiy Vladimir , Vagin Oleg , Gavrilov Boris , Goryainov Konstantin , Osipenko Anatoliy , Fedorov Aleksandr , Chernikov Valeriy , Chechetin Andrey
Published: January 2022

The publication is an article-by-article commentary on the Federal Law "On Operational Investigative Activities", taking into account the changes made to it. The commentary has been prepared on the basis of the current Russian legislation. It makes extensive use of acts of international law, decisions of the Constitutional Court of the Russian Federation on operational investigative activities.
For law enforcement and intelligence officers, judges, lawyers, students, graduate students, university professors and anyone interested in this topic.
Legal regulation of interethnic relations in the Russian Federation: problems of theory and practice
Authors: Andrichenko Lyudmila , Postnikov Aleksandor , Vasil'eva Liya , Gaunova Zhanna , Nanba Saria , Nikitina Elena , Pashencev Dmitriy , Plyugina Inna , Hludeneva Natal'ya
Published: January 2022

The scientific and practical manual analyzes the issues of legal regulation of almost all areas of implementation of the state national policy defined in the Strategy of the State National Policy of the Russian Federation for the period up to 2025, in order to ensure the interests of the state, society, man and citizen, strengthening the state unity and integrity of the Russian Federation.
The subject of the book is determined by the system of building the legal foundations of state national policy in accordance with the principles of federalism and local self-government, taking into account international standards and the experience of legislative regulation of foreign countries. The study was conducted in the context of the transformations of Russian legislation related to the adoption of amendments to the Constitution of the Russian Federation in 2020. Solutions are proposed to a number of legal issues of the implementation of the state
national policy, which can increase its effectiveness.
For state and municipal employees, specialists in the field of state national policy, researchers, teachers, graduate students and students of higher educational institutions, as well as a wide range of readers.
Digital financial assets, their origin, development and prospects in the Russian financial market
Authors: Lanskov P , Murashov M , Lanskov D
Published: January 2022

The article discusses the economic, legal and technological foundations of the emergence of digital financial assets (CFAs) in the Russian financial market. The interrelation of the CFA and blockchain technology, which is a special case of the implementation of distributed ledger technology, is analyzed. From these positions, a vision of the role and place of cryptocurrencies in the future global economy is proposed. It is emphasized that the spread of cryptocurrencies has largely contributed to the popularization of the underlying blockchain technology, the declared advantages of this technology have been investigated. The practical aspects of the application of distributed registry technology in the context of Russian legislation are analyzed. As promising and alternative forms of CFA, the issue and placement of which is possible with the participation of securities market registrars, CFA certifying the possibility of exercising rights under equity securities, the right to demand the transfer of equity securities (tokens) and CFA directly certifying the rights to participate in the capital of a joint-stock company (digital shares) are considered. It is suggested that the global trend towards digitalization and the public need to improve the protection of investors' rights may lead to the transformation of undocumented shares into digital ones. The authors believe that digital shares in the form of CFA retain the advantages of non-documentary securities, but at the same time return the uniqueness of each individual share, as in the case of documentary securities, which much more reliably records their belonging to a specific owner.
Psicoanálisis y Revolución rusa: notas para un debate
Authors: Macari Maria Lucia , Weinmann Amadeu de Oliveira
Published: January 2022

Este artículo recupera algunos momentos importantes de los encuentros y desajustes entre el psicoanálisis y la Revolución rusa. No es casualidad que el psicoanálisis haya jugado un papel crucial en los primeros años de la Revolución, haciendo espacio para la reflexión sobre el nuevo hombre soviético. De esta manera es que Wilhelm Reich visita la URSS en 1929, afirmando que muchos de los cambios introducidos por la Revolución estaban en línea con sus teorías. Sin embargo, poco después critica el retroceso en el campo de la sexualidad, que ocurriódesde la década de 1930, al que le atribuye un papelimportante en la burocratización de la Revolución.En este sentido, Reich no difiere mucho de Freud, quien en varios puntos de su carrera intelectual hacereferencia a la experiencia soviética y es escépticosobre la univocidad de las cosmovisiones y el carácter ilusorio de las promesas de extinción del malestar. Si consideramos relevante reanudar este debate, es porque plantea para el psicoanálisis la cuestión de su posibilidad de escuchar voces históricamente proletarizadas y, para los revolucionarios sociales, el problema de mantener un discurso que no sea seducido por la tentación totalizante.
Integrating Textual Information into Models of Choice and Scaled Response Data
Authors: Kim Hyowon , Allenby Greg M.
Published: January 2022

This paper proposes a new approach to modeling heterogeneity in choice data that can accommodate fixed-point ratings data and text.
Explotación y precariedad sociolaboral, la realidad de las personas migrantes trabajadoras en agricultura en España
Authors: Briones Vozmediano Erica , González-González Agustín
Published: January 2022

El trabajo agrícola de temporada en España se caracteriza por un gran desgaste físico, un bajo requerimiento de cualificación y unas precarias condiciones laborales. Estos elementos han generado que los autóctonos hayan ido abandonando paulatinamente este nicho laboral para ser remplazados por migrantes internacionales de una amplia variedad de orígenes. Otra particularidad de este mercado laboral es la corta duración de los puestos de trabajo al vincularse con las temporadas de cosecha del producto agrícola. Así, a lo largo del año, diferentes campañas que atraen a miles de personas en la búsqueda de un trabajo, desde la recolección del fruto rojo en Huelva hasta a la cosecha de la fruta dulce en Lleida durante el verano, pasando por la agricultura intensiva de mayor duración como la horticultura murciana y almeriense. El movimiento constante entre las diferentes explotaciones agrarias ha llevado a que este colectivo sea conocido como los temporeros.
Validación en trabajadores peruanos de la versión ultra reducida del Utrech Work Engagement
Authors: Calderón-De La Cruz Gustavo Alexis , Merino Soto César , Reyes Ayala Ioanna , Luna Yon Katherin Victoria
Published: January 2022

Evaluar los efectos positivos de los factores psicosociales del trabajo es una permanente iniciativa de investigadores y profesionales. El objetivo del estudio es examinar psicométricamente la versión ultra reducida del Utrech Work Engagement Scale (UWES-3). Participaron 200 trabajadores de 21 a 53 años procedentes de la ciudad de Lima (Perú). Las evidencias de validez corroboradas fueron su estructura interna y su relación con otros constructos; los coeficientes alfa de Cronbach (α), Omega (ω) y H fueron los estimadores para la confiabilidad. Como resultados, se demostró la unidimensionalidad del UWES-3 y su asociación negativa con el síndrome de burnout; los niveles de confiabilidad en los tres estimadores fueron altos. Los resultados iniciales de validez y confiabilidad del UWES-3 pueden considerarse satisfactorios e incentivan a la continuidad de su estudio en el trabajo peruano.
Alergia ocupacional en el cultivo del melocotón
Authors: Somoza María Luisa
Published: January 2022

Entrevista a María Luisa Somoza
The importance of understanding air pollution in nursing practice
Authors: Henry Heather
Published: January 2022

Heather Henry explains how this environmental threat is affecting the nation's health
Responsibility optimization of a high-speed InP/InGaAs photodetector with a back reflector structure
Authors: Wang Yuxuan , Li Guanyu , Gu Xiaowen , Kong Yuechan , Zheng Youdou , Shi Yi
Published: January 2022

Top-illuminated PIN photodetectors (PDs) are widely utilized in telecommunication systems, and more efforts have been focused on optimizing the optical responsibility and bandwidth for high-speed and capacity applications. In this work, we develop an integrated top-illuminated InP/InGaAs PIN PD with a back reflector by using a microtransfer printing (µ-TP) process. An improved µ-TP process, where the tether of silicon nitride instead of photoresist, is selected to support an underetched III-V device on an InP substrate before transfer. According to theoretical simulations and experimental measurements, the seamless integration of the PD with a back reflector through µ-TP process makes full use of the 2nd or even multiple reflecting light in the absorption layer to optimize the maximum responsibility. The integrated device with a 5 µm square p-mesa possesses a high optical responsibility of 0.78 A/W and 3 dB bandwidth of 54 GHz using a 500 nm i-InGaAs absorption layer. The present approach for top-illuminated PIN PDs demonstrates an advanced route in which a thin intrinsic layer is available for application in high-performance systems.
Spectral and temporal shaping of spectrally incoherent pulses in the infrared and ultraviolet
Authors: Dorrer C. , Spilatro M.
Published: January 2022

Laser–plasma instabilities (LPIs) hinder the interaction of high-energy laser pulses with targets. Simulations show that broadband spectrally incoherent pulses can mitigate these instabilities. Optimizing laser operation and target interaction requires controlling the properties of these optical pulses. We demonstrate closed-loop control of the spectral density and pulse shape of nanosecond spectrally incoherent pulses after optical parametric amplification in the infrared (∼1053 nm) and sum–frequency generation to the ultraviolet (∼351 nm) using spectral and temporal modulation in the fiber front end. The high versatility of the demonstrated approaches can support the generation of high-energy, spectrally incoherent pulses by future laser facilities for improved LPI mitigation.
Realistic model of entanglement-enhanced sensing in optical fibers
Authors: Krueper Gregory , Yu Charles , Libby Stephen B. , Mellors Robert , Cohen Lior , Gopinath Juliet T.
Published: January 2022

Experimental limitations such as optical loss and noise have prevented entanglement-enhanced measurements from demonstrating a significant quantum advantage in sensitivity. Holland-Burnett entangled states can mitigate these limitations and still present a quantum advantage in sensitivity. Here we model a fiber-based Mach-Zehnder interferometer with internal loss, detector efficiency, and external phase noise and without pure entanglement. This model features a practical fiber source that transforms the two-mode squeezed vacuum (TMSV) into Holland-Burnett entangled states. We predict that a phase sensitivity 28% beyond the shot noise limit is feasible with current technology. Simultaneously, a TMSV source can provide about 25 times more photon flux than other entangled sources. This system will make fiber-based quantum-enhanced sensing accessible and practical for remote sensing and probing photosensitive materials.
El difícil equilibrio entre la legalidad internacional y la política exterior: la participación de las Fuerzas Armadas españolas en la intervención militar de los Estados Unidos en Irak en 2003
Authors: Lorenzo Cuesta José Antonio
Published: January 2022

Este artículo pretende demostrar que la participación de las Fuerzas Armadas españolas, llevada a cabo en el año 2003 en el territorio iraquí, se desarrolló en un escenario geoestratégico en el que la Administración norteamericana quiso afianzar su presencia como actor principal en un mundo envuelto en complejas relaciones internacionales y tras un siglo que tanto alumbró la desaparición del comunismo de la Unión Soviética, como asistió a la consolidación del fundamentalismo islámico. Mediante la utilización de los métodos sintético y deductivo, este trabajo llevará a la comprensión del alcance real de la presencia de las tropas españolas en Irak, así como de su verdadero significado político y estratégico. Tras un recorrido por los diferentes epígrafes que conforman este artículo, podrá concluirse que los ciudadanos iraquíes fueron los únicos beneficiados de esta acción, puesto que las relaciones exteriores bilaterales entre España y los Estados Unidos se vieron especialmente afectadas.
Assembly of Neuroscience to the model of mind
Authors: Liyanage Pathma
Published: January 2022

ABSTRACT

Currently, there are several mind models developed as cognitive architectures and their main focus is to explain mind functions. However, few architectures explain the neural basis of the mind. Also, neuroscience explains the neural basis of the brain and is directly related to the mind. The study objective was to identify a mind model with a neural basis established in the model. Therefore, the study uses a systematic review of existing literature to find a mental model with a neural basis.

There are 300 articles identified in searching databases of PUBMED and Google Scholar. After duplicated removal, initial screening was done using an independent reviewer and remaining full-text articles were submitted to eligibility assessment. From the assessed full-text articles, 9 full-text articles were selected for synthesis. From those selected architectures, considering the richness of mental functions and richness of neurological assemblies, features of the architectures op of ACT-R (Adaptive control of thoughts – Rational) cognitive architecture, Leabra cognitive architecture and an embodied cognitive-affective architecture select for inclusion in the final model.

The central structure of the mind is the amygdala. It gets sensory inputs through the sensory cortex and external stimuli through the thalamus. It processes those inputs using working memory as mPFC and dLPFC. After processing, the amygdala provides output as behavior.

Also, brain structures of the partial cortex, cortex, para hippo cortex, perirhinal cortex, entorhinal cortex, subiculum, dentate gyrus, CA1 and CA3 areas of the hippocampus are used for memory encoding, memory retrieval, and critical learning. Overall, the posterior cortex processes the sensory and semantic information. The hippocampus works as episodic memory. The frontal cortex works as active maintenance of the thinking process. The basal ganglia works as action selection and the main part of the thinking process. This reveals the mind model with neurological circuit assemblies to it. The final model will limit to features of the currently existing literature.
Simulation and Control of Virtual Power Plant for Effective Utilization of Distributed Generation
Authors: Machhi Tushar
Published: January 2022

With the growing popularity of virtual power plant, few problems are encountered if penetration of virtual power plant increases in the distribution network like reverse power flow, interference caused with the controlling mechanism of voltage regulating devices, power quality issues at the PCC which are caused by irregular and unreliable injection. This project proposes an alternative injection strategy for decentralized virtual power plant in the distribution network. This strategy lets the virtual power plant act like a typical power plant and makes the system capable to regulate its terminal voltage by injecting only the required power. Such type of predictive injection lets an easy coordination between control mechanisms of various voltage regulating devices and reduces power quality issues. Also virtual power plant can be operated as a small base load plants which inject power throughout the day and/or supply few hours of peak load depending on the adopted injection strategy. Another advantage is the creation of a small micro grid. A design example of the proposed system is discussed in this project.
Organ donation
Authors: Sharma Ruchi
Published: January 2022

Introduction: Organ donation is one of the finest therapeutic marvels of the 20th century which has saved the lives of several patients. The disparity between the enormous demands for the organs and their impoverished supply is the main concern. The total organ donation shortage in our country can be met even if only few victims involved in fatal accidents produce as organ donors. Objectives: To assess the existing knowledge regarding organ donation among students, to determine the effectiveness of structured teaching program on knowledge regarding organ donation among students, to find out association between post-test knowledge scores with their selected demographic variables. Methodology: A pre-experimental study was conducted among students in Government Degree College Sanjauli, Shimla (H.P.). Sample of 60 students were chosen using convenient sampling technique. Data was assembled using self-structured questionnaire related to organ donation. The gathered data was analyzed by using descriptive and inferential statistics. Results: The study findings unveil that 42 (70%) had poor knowledge, 18 (30%) had fair knowledge and none of them had good knowledge in pre-test. In post-test 2 (3.3%) had poor knowledge, 49 (81.7%) had fair knowledge and 9 (15%) had good knowledge. The study findings also revealed that there was a significant improvement in the post-test. The mean score of knowledge in pre-test was 17.30 and in post-test was 27.53 with ‘t’ value 16.210 which was significant at ‘p’ <0.001. Conclusion: The study concluded that structured teaching program was effective in remodeling knowledge regarding organ donation among students.
Taming Runway Climate Change: A Discourse Analysis of the Address of Bahrain Crown Prince at (COP 26)
Authors: Gomaa Yasser  A.
Published: January 2022

Using Fairclough’s (1992) three dimensional approach to critical discourse analysis and Dryzek’s (2013) concepts of discourse, the article at hand analyses the 511- word address of His Royal Highness Prince Salman bin Hamad Al Khalifa, the Crown Prince and Prime Minister of the Kingdom of Bahrain, at the 26th UN Climate Change Conference (COP 26) held in Glasgow, Scotland on November 2, 2021.
The Differences of Lipoprotein-Associated Phospholipase A2, Apolipoprotein B and Low Density Lipoprotein In Obese and Lean Men
Authors: Yuliana Yuliana , Adipireno Purwanto , Limijadi Edward Kurnia Setiawan , Widyastiti Nyoman Suci , Retnoningrum Dwi
Published: January 2022

ABSTRACT Background: An increase in fat accumulation in obesity has been suggested to link with an increase in inflammation. This inflammation may be associated with an elevated of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2), Apolipoprotein B (Apo B), and Low-Density Lipoprotein (LDL), thereby associated with the risk of atherosclerosis.Objective: To investigate the differences between Lp-PLA2, Apo B, and LDL levels in obese and lean men.Methods: A cross-sectional study was conducted on 74 men (obese and lean) at the Faculty of Medicine, Diponegoro University, Indonesia, in 2020. The concentration of LDL was measured using the homogenous enzymatic colourimetric method, whereas the levels of Lp-PLA2 and Apo B were determined using the ELISA method. Data were analyzed using an Independent t-test, setting statistical significance at p <0.05.Results: This study showed that Lp-PLA2 levels were significantly different between obese and lean men (p = 0.039). Furthermore, LDL levels were also significantly different between obese and lean men (p = 0.002). However, we did not find any differences in Apo B between obese and lean men (p = 0.640).Conclusion: Lp-PLA2 and LDL levels were slightly higher in obese compared to lean men, but no difference of Apo B.
The Effectivity of Thymus vulgaris Extract on IL-1 Level and Bacterial Count in The Heart of Balb-c Mice Infected with MRSA
Authors: Nitihapsari Galuh Yulieta , Farida Helmia , Sofro Muchlis Achsan Udji
Published: January 2022

Background: The increasing phenomenon resistance of bacteria to various types of antibiotics, for example MRSA (Methicillin Resistant Staphylococcus aureus) became a serious problem. Over the last few decades S. aureus has become the dominant cause of endocarditis. MRSA data in Indonesia are still rarely reported. This has led to the importance of extracting natural substances that have anti-bacterial effects or that modulate immune response such as Thymus vulgaris (TV). It was hypothesized that TV can overcome MRSA infection by increasing IL-1, which is the initial cytokine in a natural immune response stimulated by the presence of S. aureus. Objective: This study was to investigate the effect of Thymus vulgaris extract on IL-1 and bacterial counts in the heart of balb-c mice infected with MRSA. Methods: There were 30 male Balb-c mice randomly divided into six groups. Group K (mice infected with MRSA without treatment),P1(mice treated with TV extract 7 days later infected with MRSA), P2(mice infected and treated with vancomycin), P3(mice infected and treated with TV+vancomycin extract), P4(mice infected and treated with amoxicillin), and P5 (mice infected and treated with TV extract+amoxicillin). IL-1 and bacterial count was assessed by ELISA and microbiological culture. Results: The result showed that there was a significant increase in IL-1 between groups (p=0.001).The median decrease in the bacterial count in the heart was 0 in almost treatment group except for P4 group which its median was 26.000 (p=0.161). The correlation between IL-1 levels and MRSA count in the heart had a weak negative correlation (r=-0.182). Conclusion: Thymus vulgaris extract was effective to  increase IL-1 levels significantly but was not proven to decrease MRSA count in the heart of balb-c mice.
Reliability Analysis of Diesel Engine at LNG Plant using Counting Process
Authors: Darmanto Seno , Atmanto Ireng Sigit , Permana Bagus Hendra
Published: January 2022

The purpose of this research is to analyze the reliability of diesel engine as driver for fire water pump. To determine the reliability level of the diesel engine, this research will apply counting process so that the rate of failure of the diesel engine can be known. The data used as basis for calculation is failure data gained from maintenance work order databases from 2012 to 2017. The data obtained will be processed using counting process method to produce mathematical modeling to predict the amount of failure to diesel engines in the future. From 4 diesel engines, only 3 parametric failure rate (l) that could be generated,  for 33-GE-5A,  for 33-GE-5B, and  for 33-GE-5C, since 33-GE-5D was severely damaged in September 2015.   The mathematical modeling will be verified using the Pearson's Chi-squared Test method to ensure the validity of the mathematical model can be guaranteed. The result of the goodness of fit test shows that only parametric failure rate (l) for 33-GE-5B and 33-GE-5C that could be accepted. The outcome mathematical model will be used to predict future behavior and failure of the unit so effective and efficient maintenance strategy for 33-GE-5B and 33-GE-5C could be applied
Gankyrin has a potential role in embryo implantation via activation of STAT3
Authors: Yu Min , Peng Xiandong , Li He , Xu Yining , Sun Xiaoxi , Chen Jiazhou
Published: January 2022

Embryo implantation, a critical step during the mammalian reproductive process, requires normal developing blastocysts and a receptive endometrium. Endometriosis, a common pathologically benign gynecological condition, is associated with decreased fertility and reduced endometrial receptivity. The oncoprotein, Gankyrin, has been associated with endometriosis and endometrial cancer. Here, we examined the role of Gankyrin during the process of embryo implantation and found that Gankyrin expression levels were significantly increased during the mid-secretory phase, but unaffected during the proliferative phase in the human endometrium. Using an in vitro cell adhesion assay to examine the cell adhesion rate of BeWo trophoblast spheroids to Gankyrin knockdown or overexpressing human endometrial carcinoma RL95-2 cells, we demonstrated that the adhesion rate was significantly reduced in Gankyrin-knockdown RL95-2 cells, while overexpression of Gankyrin promoted cell adhesion. Furthermore, we found that the downregulation of Gankyrin inhibited STAT3 activation and subsequent matrix metalloproteinase 2 (MMP2) expression, while overexpression led to STAT3 activation and MMP2 expression. In vivo, we found that Gankyrin expression was increased in the endometrium after conception but decreased with the prolongation of gestation time in female mice. siRNA-mediated knockdown of Gankyrin in the uterine horn led to a significant reduction in the number of implanted embryos 9 days post-gestation, which was associated with a decrease in p-STAT3 expression and MMP2 transcription. Taken together, our findings indicate that Gankryin has a potential role in embryo implantation via STAT3 activation.
LINC02190 inhibits the embryo–endometrial attachment by decreasing ITGAD expression
Authors: Zhao Feiyan , Chen Tong , Zhao Xuehan , Wang Qin , Lan Yonglian , Liang Yu , Li Ying , Wang Shuyu , Yang Yang , Yang Xiaokui
Published: January 2022

Recurrent implantation failure (RIF) is a challenge in the field of reproductive medicine, but mechanisms for its occurrence remain still unclear. Long non-coding RNAs (lncRNAs) have been found to play a vital role in many different diseases. In recent years, the differentially expressed lncRNAs have been reported in endometrial tissues. Here, we profiled dysregulated lncRNAs and mRNAs in the endometrial tissues of RIF patients and performed correlation analysis. We found that LINC02190 was upregulated in RIF endometrium and was bound to the integrin αD (ITGAD) mRNA promoter. Immunofluorescence assays were used to detect the location of ITGAD in the Ishikawa cell line and patients’ endometrial biopsies. Overexpressed LINC02190 could decrease the expression of ITGAD and the adhesion rate of Ishikawa and JAR cells. Knockdown of the expression of LINC02190 significantly increased the ITGAD level, as well as the adhesion rate of Ishikawa and JAR cells. Furthermore, we demonstrated that the 150–250 bps of LINC02190 were the cis-elements involved in the regulation of ITGAD promoter activities. In conclusion, the results demonstrated that LINC02190 plays an important role in the occurrence of RIF, and the molecular mechanism may be associated with the embryo–endometrial attachment mediated by ITGAD. This study emphasizes the importance of lncRNAs in the occurrence of RIF and provides a potential new biomarker for diagnosis and therapies.
EUGENIO F. GRANELL EN “LA VOZ DE GUATEMALA”, LA DIVULGACIÓN RADIOFÓNICA POLÍTICA Y CULTURAL EN LA DIÁSPORA
Authors: Real López Inmaculada
Published: January 2022

En este artículo se analiza la faceta periodística de Eugenio F. Granell en la emisora de radio “La Voz de Guatemala”. Se presta atención a los cambios que se produjeron en los contenidos de estas emisiones que en sus inicios eran de carácter político y terminaron siendo exclusivamente culturales. Destacamos la crítica de arte, pues tiene una presencia relevante porque paralelamente Granell la desarrolló en otros medios, a la vez que exploraba el lenguaje plástico y se integraba en el ambiente cultural guatemalteco, protagonizado por el grupo AGEAR y Skar-Ti, y del que quedó desvinculado por sus confrontaciones ideológicas que le obligaron a huir del país
Estrategias de marketing en el canal intermedio y posicionamiento para el sector de empresas comercializadoras de GPS en el Perú periodo 2018 - 2020
Authors: León Ratto Augusto Gerardo
Published: January 2022

El canal intermedio representa un alto nivel de rentabilidad para las empresas comercializadoras de GPS, debido a sus alianzas estratégicas con las aseguradoras para obtener la base de datos de los clientes que requieren la instalación del GPS de manera obligatoria antes de recibir sus autos nuevos y que serán derivados de manera automática a sus empresas. Por lo cual, la presente investigación tiene como objetivo comprobar la relación que existe entre las estrategias de marketing del canal intermedio y el posicionamiento de las empresas que brindan servicio de GPS en todo el Perú para el periodo 2018 - 2020. El enfoque ha sido cuantitativo; diseño no experimental, descriptivo, correlacional y longitudinal, siendo el cuestionario, el instrumento de recopilación de datos que fue aplicado en una muestra de 168 clientes con servicio de GPS. Demostrando con los resultados obtenidos, la existencia de una relación de estrategias de marketing orientada al canal intermedio y el posicionamiento de las empresas que comercializan GPS en Perú, con un valor de Chi cuadrado de 334,868 y un nivel de significación de 0.001, siendo esta muy alta. Por tanto, la creación de alianzas estratégicas es una necesidad para obtener una mayor rentabilidad en las aseguradoras vehiculares y el mejor posicionamiento de las empresas de GPS.
El Núcleo del Operador Trazo de Orden m
Authors: Roman Tello Hubert , Santiago Ayala Yolanda
Published: January 2022

En este trabajo estamos interesados en demostrar que el núcleo del operador Trazo de orden m, es el espacio H0m (Ω) con Ω abierto acotado bien regular, inspirados por los resultados mostrados por M. Cavalcanti [14]. Finalmente, damos algunos comentarios.
Una teoría de cohomología local generalizada
Authors: Caro Tuesta Napoleón , Durán Quiñones Sofía Irena , Mendoza Quispe Wilfredo
Published: January 2022

En este trabajo introducimos ciertos funtores de cohomología local que generalizan los estudiados en [9]. Demostramos que sus módulos de cohomología local pueden ser obtenidos como los módulos de cohomología de un complejo de Cech generalizado. También proponemos una noción de homología local. En este contexto probamos que la homología local de un módulo Matlis reflexivo (en el sentido de [2]) se puede expresar como el límite inverso de determinados módulos Tor.
Estimaciones de Respuesta al Ítem de los Parámetros de una Medida Breve de Bienestar Psicológico Estudiantil en el Contexto Universitario
Authors: Franco Mendoza Josué Michael
Published: January 2022

El propósito del presente estudio fue el de construir una escala breve de bienestar psicológico en el contexto universitario, en fase preliminar. Para ello se contó con la participación de 417 estudiantes de la facultad de educación de una universidad pública de Lima, de ambos sexos, con edades oscilantes entre los 17 y 35 años (M = 23, D.S. = 1.86). Se trabajó con los tópicos de Salud Mental (SM) y el de Familia y Relaciones Interpersonales (FR). El método fue instrumental, contando con una escala de 35 ítems y siete componentes, aprobada por cinco expertos a través del estadístico V de Aiken, con 3 criterios de valoración (V = .83, 1.00). Los ítems pasaron por diferentes procesos de análisis en las estimaciones de parámetros con el modelo de dos parámetros logísticos (2PL) de la Teoría de Respuesta al Ítem (TRI), en contraste con indicadores de la Teoría Clásica de los Test (TCT), a partir del Análisis Factorial Confirmatorio (AFC) y medidas de consistencia interna. Los resultados evidenciaron que los componentes de la escala ajustaron adecuadamente al modelo de 2PL (x2 = .58, 1.73, p > .05), cumpliéndose los supuestos de unidimensionalidad e independencia local para los ítems por cada componente. Así también se reportaron funciones de información de los mismos, las cuales fueron complementadas con evidencias del ajuste de los AFC para cada tópico (x2/gl = 1.18, 2.45, GFI = .99, 1.00, TLI = .94, .99, CFI = .95, .99, NNFI = .94, .99, RMR = .001, SRMR = .05, .06, RMSEA = .02, .06). Por otra parte, las medidas de consistencia interna oscilaron entre .61 y .82, tomando como indicadores el coeficiente Omega y KR-20. Se recomienda continuar realizando revisiones del modelo, en una siguiente fase del estudio, a la vez de complementar análisis con componentes orientados a necesidades educativas y el desarrollo de habilidades blandas.
Evaluación del YM976 como alternativo a las hormonas gonadotrópicas en la maduración in vitro de oocitos bovinos y su competencia para el desarrollo embrionario
Authors: Carrillo-Gonzalez Diego Fernando , Hernández Herrera Darwin Yovanny , Vásquez Araque Neil Aldrin
Published: January 2022

El objetivo del estudio fue evaluar el efecto del YM976 como inhibidor específico de la fosfodiesterasa tipo 4 (PDE-4) sobre la maduración in vitro de oocitos bovinos y su capacidad de desarrollo embrionario. Para ello, complejos cúmulo-oocito se obtuvieron por aspiración folicular de ovarios obtenidos en planta de sacrificio. Se maduraron in vitro por 24 horas en medio TCM-199 suplementado con cuatro concentraciones de YM976 (1, 10, 100 y 1000 nM) o con gonadotropinas (LH y FSH). Se evaluó la expansión del cúmulo por observación visual y la reanudación de la metafase II por tinción con colorante Hoechst. Los oocitos fueron fertilizados y cultivados en medio KSOM Evolve por ocho días. El porcentaje de expansión grado 3 de las células de cúmulo en oocitos cultivados con gonadotropinas fue diferente (p= 0.00016) respecto de los cultivado en presencia del YM976. La reanudación de la metafase II fue similar entre oocitos madurados a 10 nM de YM976 y los madurados con gonadotropinas. Los oocitos madurados en concentraciones de 1 y 10 nM de YM976 presentaron un desarrollo embrionario temprano similar al encontrado en los madurados con gonadotropinas. Por el contrario, altas concentraciones de YM976 tuvieron efectos deletéreos. En conclusión, concentraciones 1 y 10 nM del inhibidor de PDE-4 YM976 durante la maduración in vitro de oocitos retrasa la expansión de las células de la granulosa, pero permite una maduración nuclear y competencia para el desarrollo embrionario, similar a los oocitos madurados con gonadotropinas, sugiriendo que, el uso de YM976 puede ser aplicado en procesos de maduración in vitro de oocitos bovinos.
Uso terapéutico del cannabidiol en animales de compañía. Percepción de profesionales veterinarios de Guayaquil, Ecuador
Authors: Rázuri Zambrano Illona , Rugel González David
Published: January 2022

El objetivo de la investigación fue determinar la percepción de los profesionales veterinarios de la ciudad de Guayaquil con respecto al uso terapéutico del cannabidiol en animales de compañía. Se realizó una encuesta anónima y voluntaria a profesionales veterinarios que culminaron sus estudios en la Universidad Agraria del Ecuador entre 1992 y 2020 y que se encontraban laborando en la ciudad de Guayaquil. Se obtuvieron 305 encuestas válidas de las cuales el 93% (286) manifestaron estar de acuerdo con la aplicación de cannabidiol para usos terapéuticos tales como manejo del dolor, ansiedad, afecciones músculo esqueléticas, convulsiones, neoplasias y cuidados paliativos; además indicaron que las presentaciones más aceptadas se dan en forma de gotas bebibles y tabletas. Mediante la prueba Chi cuadrado se identificaron relaciones entre la percepción del uso del cannabidiol y el género de los encuestados en usos particulares como ansiedad, convulsiones, fobia a truenos o fuegos artificiales, enfermedades gastrointestinales, neoplasias y anorexia. La investigación determinó que la percepción de la mayoría de los profesionales veterinarios es positiva con respecto al uso del cannabidiol como agente terapéutico.
Determinación de residuos de tetraciclina en carne de cerdos beneficiados en dos camales de Lima (2018)
Authors: Huanilo Tarazona Jehason , Morales-Cauti Siever
Published: January 2022

El objetivo del estudio fue determinar la presencia de residuos de tetraciclina en la carne de cerdo en dos camales de Lima durante 2018. Se procesaron 25 g de carne del cuello de 402 cerdos beneficiados. Las muestras fueron obtenidas en la etapa de oreo y se evaluó mediante la técnica microbiológica de difusión enfrentando las muestras a la cepa de Bacillus subtilis ATCC 6633. Posteriormente se confirmó la presencia de tetraciclina mediante la técnica de ELISA MaxSignal Tetracycline Test Kit. No se encontraron muestras positivas a la prueba microbiológica de difusión. El 7.32% (6/82) resultó positiva a una concentración de tetraciclina entre 1587 y 5811 ppb. Ninguna de las muestras positivas superó los límites permitidos en el país.
Housing Finance and Markets Dynamics in Tanzania
Authors: Mushi Vianey John
Published: January 2022

This study examines whether feedback from housing price shocks factored into the availability of mortgage credit in Tanzania between 2008 and 2018. This was done by estimating a Vector Error Correction Model (VECM) with mortgage financing and using three measures of house pricing trends in the luxury, mid-end and economy sub-markets as dependent variables. Results showed that mortgage credit expansion is related to housing price growth in the long-run, but the impact mostly ran from housing price shocks to mortgage growth. In the short-term, changes in price for luxury houses led to a mortgage growth in the first quarter after the shocks, which in turn stimulated changes in housing prices. However, variations on mortgage credit flows had a more significant short-term impact on prices of housing units than it did for houses priced on mortgage credit. The dynamic response between mortgage credit flow and housing prices disappeared when housing price indicators for the economy and mid-end sub-markets were used in the analysis. In addition, both mortgage credit and housing markets were highly persistent, but the effect of previous shocks lasted longer in the mortgage lending process. The paper concludes that the substantial increase in housing prices might be a major concern for policymakers, in particular, because it foreshadows a mortgage crisis.
Market Rent Determinants of Residential Apartments in Addis Ababa, Ethiopia
Authors: Belete Masresha , Yilma Mesfin
Published: January 2022

Rapid urbanisation and population growth increase the demand for housing. Given its importance to human wellbeing, the right to housing is recognised in international, regional and domestic legislation. The rental housing sector is the major form of housing tenure in Ethiopia. Given financial constraints, Ethiopian tenants tend to rent instead of buying property. However, there are no well-developed procedures that guide how rental value is determined in Ethiopia. As such, the purpose of this study is to identify monthly rent determinant variables of residential apartments in Ethiopia. Substantial empirical results from different countries indicate that rental value is a result of the combined contribution of the integrated components: property, amenities, and externalities. For this study, a multiple regression model was used for 164 samples taken from three purposefully selected case study areas in Addis Ababa (CMC, Jemo and Kazanchis). The regression results indicate that nine significant variables were determinant variables of monthly rent at a 95% confidence interval. This study may contribute decisive information for Ethiopian property managers, real estate developers, income tax assessors, real property owners, lending institutions and other interested real estate professionals. It allows these stakeholders to more accurately estimate the monthly rental value and market value of properties for their business evaluation.
Editorial
Authors: Olaleye Abel
Published: January 2022

The Journal of African Real Estate Research (JARER) continues to be an exciting outlet for authors across Africa to propagate the results of their research activities. This is the fifth volume and first issue for 2020 as well as the first issue under the stewardship of our reconstituted editorial board. I would like to take this opportunity to welcome them all to the journal and I have no doubt that their expert knowledge and experience will continue to steward the ascension of JARER as the premier publication on real estate related research in the African continent. In other news, we are in the process of developing a special issue highlighting the work of early career female researchers in real estate. Supporting female researchers in real estate is an important agenda for the real estate discipline and is strongly supported by the editorial team. The guest editors for the special issue are Karen Gibler and Geci Karuri-Sebina and publication is planned for April 2021. If you are interested in publishing your work in the special issue, please contact the co-editors or the managing editor.