bluuebunny/crossref_metadata_2025 huggingface dataset:
El valor estratégico de los acuerdos de colaboración para la adquisición de conocimiento en innovación abierta. Un análisis del sector de las tic en España
Authors: Calderón Martínez María Guadalupe
Published: August 2020

La apertura de las fronteras organizacionales para obtener ideas o generar mecanismos alternativos de salida al mercado permite identificar nuevos elementos en la gestión de la innovación. En este trabajo se plantea cómo, a partir de la liberalización del sector de las Tecnologías de la Información y de las Comunicaciones (TIC) en España, las empresas adoptan modelos que motivan la incorporación de conocimientos y agentes externos. La aportación de este artículo es la identificación de los elementos que se relacionan con el establecimiento de acuerdos de colaboración en innovación mediante el análisis de la información contenida en patentes.
Editorial Número 234
Authors: López Herrera Francisco , García Narváez José Alberto
Published: August 2020

En un contexto de fuerte competencia, el análisis minucioso y preciso de las relaciones mercado-producto es un elemento indispensable para el diseño de estrategias de mercado que puedan contar con buenas probabilidades de éxito. Johan H. Martínez, Hugo Alberto Rivera R., Carlos E. Maldonado y Rubén Iván A. Mendoza presentan su trabajo de investigación Adquisición de ventajas competitivas mediante la generación de un territorio estratégico. En él se muestra la propuesta mediante la cual dichos autores mejoran las herramientas disponibles para el análisis de la estructura del sector estratégico que permite identificar nuevos espacios de mercado a los que la empresa puede dirigir sus esfuerzos mejorando su posicionamiento estratégico. Basándose en la teoría de la complejidad y en desarrollos previos en el campo del análisis de sectores estratégicos, los autores de este artículo muestran cómo se pueden analizar la satisfacción de necesidades, el uso de los canales de distribución y las variedades de productos para identificar oportunidades que actualmente no han sido aprovechadas como áreas no explotadas o como nuevos nichos a los que se podría acceder mediante nuevos productos, servicios que agreguen valor a los productos ya existentes o nuevos canales de distribución.
El valor de la marca desde la perspectiva del consumidor Estudio empírico sobre preferencia, lealtad y experiencia de marca en procesos de alto y bajo involucramiento de compra
Authors: González Hernández Eva M. , Orozco Gómez Ma. Margarita , De la Paz Barrios Alejandra
Published: August 2020

El principal objetivo de este estudio es entender la relación entre un conjunto de dimensiones propuestas en el modelo customer- based brand equity, o cbbe (por sus siglas en inglés): conocimiento, relación y actitud hacia la marca, así como preferencia de marca desde diferentes niveles de involucramiento en el proceso de compra. Específicamente, el principal propósito de este estudio es entender la relación existente entre: a) la preferencia de marca y la evaluación delos atributos por parte del consumidor; b) la preferencia de marca y la lealtad a la misma; y finalmente, c) la preferencia de marca y la experiencia de marca. Para poder entender los diferentes niveles de involucramiento en el proceso de compra, se seleccionaron tres categorías de productos: laptops (involucramiento alto), teléfonos celulares (involucramiento medio) y bebidas gaseosas (involucramiento bajo). Se aplicó una encuesta a 341 estudiantes de una escuela de negocios y en  cadacategoría se compararon las cinco marcas más populares. Los resultados muestran evidencia de que el nivel de involucramiento en el proceso de compra es un factor relevante para entender la evaluación del consumidor, la preferencia, actitud, lealtad y experiencia de marca.
Calidad de las tecnologías de la información y competitividad en los hoteles de la península de Yucatán
Authors: Caro Encalada Manuel J. , Leyva Morales Carlos E. , Vela Manzanilla Raúl
Published: August 2020

En este trabajo se analiza mediante un modelo econométrico el impacto del nivel de calidad en el uso de las tecnologías de la información y la comunicación (tic) sobre el grado de competitividad del sector hotelero en la península de Yucatán. Los ocho modelos desarrollados explicaron en forma adecuada y suficiente que el uso de las tic con una adecuada capacitación de los usuarios de estos sistemas, un correcto valor de utilización, un apropiado grado de informatización y un pertinente nivel de seguridad informática influyen de manera importante en el porcentaje de ocupación media en las empresas hoteleras de la península de Yucatán incrementándolo; sin embargo, éstas requieren identificar sus recursos y capacidades para poder enfrentar adecuadamente la demanda de los servicios que ofertan en mejores condiciones que sus competidores.
Mengkaji Ulang Makna Hadits ”Surga di bawah Telapak Kaki Ibu” dalam Perspektif Islam
Authors: . Romlah
Published: August 2020

Mengkaji Ulang Makna Hadits ”Surga di bawah Telapak Kaki Ibu” dalam Perspektif IslamRomlah1Jurusan Tarbiyah Fakultas Agama Islam Universitas Muhammadiyah Malang, Jln. Raya Tlogomas no. 246, Malang 65144; *Email : romlah@umm.ac.id Abstract :Pemberian makna hadits ini dilatarbelakangi oleh realitas akan keberadaan  kaum perempuan secara jeneral pada saat sebelum datangnya Islam hingga sekarang sangat tidak berpihak kepada perempuan, meski sebagian besar mereka telah melakukan berbagai perubahan, demi menggapai kesempurnaan sebagai insan kamil (manusia sempurna). Diantaranya dengan menambah ilmu pengetahuan, baik melalui pendidikan formal (sekolah dari jenjang TK – PT), non formal (mengikuti kursus, pelatihan dan lain-lain sesuai dengan bakat dan minatnya atau tuntutan kerja) dan in formal (pengasuhan, pemberian pemahaman dan pengarahan oleh orang tua di rumah). Keywords :Hadits ”Aljannatu tahta aqdami al-ummati”, ibu
Social-family development: integral culture for the formation of the children of the zero program always in the municipality of Pamplona
Authors: Cruz - Vega Fredy Andrés , Figueroa - Granados Luz Eliana
Published: August 2020

The research makes it possible to recognize the judgments of the users who are enrolled in the zero to always family modality and, in turn, establish the relationship they give to the program in the training of their children. The use of qualitative research for this proposal contributes or it establishes the relationship of describing and giving points of view to problems of the social educational and experiential context, the primary objective was to determine the degree of use by users of the program from zero to always family modality, in the municipality of Pamplona. It can be said that the application of this research contributes in part to diagnosing from a personal point of view the impact generated by the program in the training of minors, evidencing in it the theoretical, political and real positions in order to make them aware of the importance of training of children. The instruments used for families in certain rural areas who are the objects of study were semi-structured interviews; validated by experts from the area, they managed to produce key information for the analysis and triangulation. Thanks to the analysis units and the categories established in the interview, it was possible to focus and provide solutions to the objectives set, demonstrating the perception that the beneficiaries of the program of zero They always have in relation to the operation in rural areas of Pamplona. With the information obtained it is clear to establish the conformity of the operation of the program in terms of the role of care for families, the training of minors and the integration of society is thus how the show is getting on the right tide.
Acoso laboral e inequidad de género una problemática que afecta la comunicación de una organización
Authors: Castañeda - Hernández Danna Valentina , Guzmán - Roa Elkin Andrés , Fernández - Chavarro Leidy Giovana , Parada - Romero Diego Alejandro , Casanova – Rodríguez Harrinton Yesed
Published: August 2020

Varias organizaciones en Bogotá sufren de la inequidad laboral especialmente hacia la mujer, durante el desarrollo de este documento se empleó una encuesta a varias personas que trabajan en empresas “a b y c”, con el objetivo de determinar si al haber un tipo de acoso laboral dentro de la organización esta hace que la comunicación se vuelva nula entre sus integrantes. en el estudio que se realizó se evidencio que las mujeres son más propensas a sufrir el acoso laboral debido a que se considera que son el género más débil haciendo que en muchos casos las empresas no tomen las decisiones adecuadas y por lo que se puede decir que al presentarse este tipo de problemas entre empleados y empleadores este puede perjudicar en el rendimiento de toda la organización.
¿Un patio de contenedores, en el Oriente Antioqueño?
Authors: Ceballos - Ramírez Silvia Liliana , Guisao - Giraldo Érica Yaneth
Published: August 2020

La utilización del contenedor

La utilización del contenedor desde la década de los cincuenta, ha generado cambios en la movilización de carga y, como resultado de los viajes de buques portacontenedores empieza la construcción de patios de contenedores o puertos secos, los cuales cobran importancia en los procesos logísticos. El propósito de este escrito es evidenciar, si un puerto seco en el Oriente Antioqueño, subregión Altiplano, aportaría a la eficiencia de los procesos de comercio exterior.  La investigación fue mixta, concluyente y analítica; se realizaron entrevistas a tres (3) patios de contenedores asentadas en el departamento de Antioquia y, se hicieron encuestas a 63 empresas asentadas en la región que realizan operaciones de importación, exportación o ambas. Se resalta que los empresarios consideran que la apertura de un patio permitirá disminuir costos y tiempos de operación y poder negociar mejores tarifas con las navieras y empresas transportadoras terrestres.  

desde la década de los cincuenta, ha generado cambios en la movilización de carga y, como resultado de los viajes de buques portacontenedores empieza la construcción de patios de contenedores o puertos secos, los cuales cobran importancia en los procesos logísticos. El propósito de este escrito es evidenciar, si un puerto seco en el Oriente Antioqueño, subregión Altiplano, aportaría a la eficiencia de los procesos de comercio exterior.  La investigación fue mixta, concluyente y analítica; se realizaron entrevistas a tres (3) patios de contenedores asentadas en el departamento de Antioquia y, se hicieron encuestas a 63 empresas asentadas en la región que realizan operaciones de importación, exportación o ambas. Se resalta que los empresarios consideran que la apertura de un patio permitirá disminuir costos y tiempos de operación y poder negociar mejores tarifas con las navieras y empresas transportadoras terrestres.
The scinderin gene (SCIN) is the direct target of miR3085-3p in chondrocytes
Authors: Le Linh , Ho Phuong , Clark Ian
Published: August 2020

MiR-3085-3p was shown to play a crucial role in cartilage biology, with potential impacts in osteoarthritis (OA). Insight into this miRNA function could be of practical importance for future miRNA-based therapy, however, little is known regarding the biological roles of this miRNA. The physiologic function of an individual miRNA is dictated through its mRNA targets, and as SCIN (scinderin, also known as adseverin) was reported to be involved in chondrocyte differentiation, maturation, and phenotype maintenance, this study aimed to prove SCIN is a direct target of miRNA-3085-3p. Bioinformatics algorithms were utilized for predicting their interacting sites. Gain- and loss-of-function experiments with miRNA-3085-3p were performed and SCIN expression was measured by real-time RT-PCR. SCIN 3?UTR regions harboring either the miR-3085-3p seed site or its mutant version were cloned into pmirGLO downstream of a reporter firefly luciferase encoding gene. The effect of miR-3085-3p on this region was determined by the luciferase assay. Four binding sites of miR-3085-3p in SCIN 3?UTR were identified. SCIN expression level was found to be inversely correlated with the level of miRNA-3085-3p. MiR3085-3p directly binds to its binding sites in SCIN 3? UTR. These data suggest that SCIN is the direct target of miR-3085-3p in chondrocyte cells.
The effect of swimming exercise on age-dependent electrophysiological changes in female rat myocardium
Authors: Ozturk Nihal , Ozdemir Semir
Published: August 2020

The effects of swimming exercise on age-associated electrical changes in female rat hearts were investigated. Four- and 24-month-old Wistar female rats were divided into three groups as follows: sedentary young, sedentary old and exercise old. Swimming exercise was performed for 8 weeks (60 min/day, 5 days/week). All recordings were taken from freshly isolated left ventricular myocytes of rat heart. Aging caused a significant increase in the size of myocytes; swimming exercise did not affect this change. The repolarization period of the action potential was prolonged in aged myocytes, but exercise training had no effect on this prolongation. Exercise suppressed the transient outward potassium currents, while the inactivation and reactivation kinetics did not change between the groups. Moreover, aging caused suppression in the inward rectifier potassium currents, and exercise increased this suppression. Consequently, changes in the action potential and potassium currents may contribute to the impaired cardiac function in the elderly female myocardium, and swimming exercise is not an effective strategy in reversing these electrical changes.
Continuous Audit Implementation at Cia. Hering in Brazil
Authors: Codesso Mauricio , de Freitas Marcelo Machado , Wang Xinxin , de Carvalho Alecsandra , da Silva Filho Aldori Acácio
Published: August 2020

This paper details the implementation of continuous audit at Cia. Hering, a large Brazilian clothing retailer, including challenges and opportunities that occurred during the process. Internal auditors used emerging technologies to improve the firm's audit procedures and implement continuous auditing in the firm's tax compliance system for its manufacturing division. By comparing internal invoice information to an exogenous tax dataset extracted directly from the State's Tax and Finance Office, internal auditors were able to review all electronic invoices for manufacturing in a timely way, improving information quality and internal controls. Continuous audit provided continuous control monitoring (CCM) and continuous data assurance (CDA) and reduced tax compliance risk in its manufacturing division.
Metabolic Syndrome and COVID-19 Mortality Among Adult Black Patients in New Orleans
Authors: Xie John , Zu Yuanhao , Alkhatib Ala , Pham Thaidan T. , Gill Frances , Jang Albert , Radosta Stella , Chaaya Gerard , Myers Leann , Zifodya Jerry S. , Bojanowski Christine M. , Marrouche Nassir F. , Mauvais-Jarvis Franck , Denson Joshua L.
Published: August 2020

OBJECTIVE

Coronavirus disease 2019 (COVID-19) mortality is high in patients with hypertension, obesity, and diabetes. We examined the association between hypertension, obesity, and diabetes, individually and clustered as metabolic syndrome (MetS), and COVID-19 outcomes in patients hospitalized in New Orleans during the peak of the outbreak.

RESEARCH DESIGN AND METHODS

Data were collected from 287 consecutive patients with COVID-19 hospitalized at two hospitals in New Orleans, LA, from 30 March to 5 April 2020. MetS was identified per World Health Organization criteria.

RESULTS

Among 287 patients (mean age 61.5 years; female, 56.8%; non-Hispanic Black, 85.4%), MetS was present in 188 (66%). MetS was significantly associated with mortality (adjusted odds ratio [aOR] 3.42 [95% CI 1.52–7.69]), intensive care unit requirement (ICU) (aOR 4.59 [CI 2.53–8.32]), invasive mechanical ventilation (IMV) (aOR 4.71 [95% CI 2.50–8.87]), and acute respiratory distress syndrome (ARDS) (aOR 4.70 [95% CI 2.25–9.82]) compared with non-MetS. Multivariable analyses of hypertension, obesity, and diabetes individually showed no association with mortality. Obesity was associated with ICU (aOR 2.18 [95% CI 1.25–3.81]), ARDS (aOR 2.44 [95% CI 1.28–4.65]), and IMV (aOR 2.36 [95% CI 1.33–4.21]). Diabetes was associated with ICU (aOR 2.22 [95% CI 1.24–3.98]) and IMV (aOR 2.12 [95% CI 1.16–3.89]). Hypertension was not significantly associated with any outcome. Inflammatory biomarkers associated with MetS, CRP and lactate dehydrogenase (LDH), were associated with mortality (CRP [aOR 3.66] [95% CI 1.22–10.97] and LDH [aOR 3.49] [95% CI 1.78–6.83]).

CONCLUSIONS

In predominantly Black patients hospitalized for COVID-19, the clustering of hypertension, obesity, and diabetes as MetS increased the odds of mortality compared with these comorbidities individually.
Metabolic Syndrome and COVID-19 Mortality among Adult Black Patients in New Orleans
Authors: Xie John , Zu Yuanhao , Alkhatib Ala , Pham Thaidan T , Gill Frances , Jang Albert , Radosta Stella , Chaaya Gerard , Myers Leann , Zifodya Jerry S. , Bojanowski Christine M. , Marrouche Nassir F. , Mauvais-Jarvis Franck , Denson Joshua L.
Published: August 2020

OBJECTIVE Coronavirus disease 2019 (COVID-19) mortality is high in patients with
hypertension, obesity and diabetes mellitus. We examined
the association between hypertension, obesity and diabetes, individually and
clustered as metabolic syndrome (MetS), and COVID-19 outcomes in
patients hospitalized in New Orleans during the peak of the outbreak.

RESEARCH
DESIGN AND METHODS Data were collected from 287 consecutive COVID-19 patients
hospitalized at two hospitals in New Orleans, Louisiana from March 30th
to April 5th, 2020. MetS was identified per WHO criteria.

RESULTS Among 287 patients (mean age, 61.5
years; female, 56.8%; non-Hispanic Black, 85.4%), MetS was present in 188
(66%). MetS was significantly associated with mortality (adjusted odds ratio
[aOR]: 3.42, 95% confidence interval [CI]: 1.52-7.69), ICU (aOR: 4.59, CI:
2.53-8.32), invasive mechanical ventilation (IMV) (aOR: 4.71, CI: 2.50-8.87)
and acute respiratory distress syndrome (ARDS) (aOR: 4.70, CI: 2.25-9.82),
compared with non-MetS. Multivariable analyses of hypertension,
obesity and diabetes individually showed no association with mortality.
Obesity was associated with ICU (aOR, 2.18, CI, 1.25-3.81), ARDS (aOR, 2.44,
CI, 1.28-4.65), and IMV (aOR, 2.36, CI, 1.33-4.21). Diabetes was associated
with ICU (aOR, 2.22, CI, 1.24-3.98) and IMV (aOR, 2.12, CI, 1.16-3.89).
Hypertension was not significantly associated with any outcome. Inflammatory
biomarkers associated with MetS, C-reactive protein (CRP) and lactate
dehydrogenase (LDH) were associated with mortality [CRP (aOR, 3.66, CI,
1.22-10.97), LDH (aOR, 3.49, CI, 1.78-6.83)].

CONCLUSIONS In predominantly Black patients
hospitalized for COVID-19, the clustering of hypertension, obesity and diabetes as MetS increased the odds of mortality
compared to these comorbidities individually.
YAP Activation in Renal Proximal Tubule Cells Drives Diabetic Renal Interstitial Fibrogenesis
Authors: Admin Ada , Chen Jianchun , Wang Xiaoyong , He Qian , Bulus Nada , Fogo Agnes B. , Zhang Ming-Zhi , Harris Raymond C.
Published: August 2020

Increasing studies have suggested that the
renal proximal tubule is a site of injury in diabetic nephropathy (DN), and
progressive renal tubulointerstitial
fibrosis is an important mediator of progressive kidney dysfunction in
DN.
In this study, we observed increased expression and activation of YAP (Yes-associated protein) in renal
proximal tubule epithelial cells (RPTC) in diabetic patient and mouse
kidneys. Inducible deletion of Yap specifically in RPTC or
administration of the YAP inhibitor verteporfin significantly attenuated diabetic tubulointerstitial fibrosis. EGFR-dependent activation of RhoA/Rock and PI3K-Akt signals and their
reciprocal interaction were upstream of proximal tubule YAP activation
in diabetic kidneys. Production and release of CTGF in culture medium were
significantly augmented in HEK293 transfected with a constitutively active YAP
mutant, and the conditioned medium collected from these cells activated and
transduced fibroblasts into myofibroblasts. This study demonstrates that proximal
tubule YAP dependent paracrine mechanisms play an important role in diabetic
interstitial fibrogenesis; therefore, targeting Hippo signaling may be a
therapeutic strategy to prevent the development and progression of diabetic
interstitial fibrogenesis.
Çimento Esaslı Harçların Fiziksel ve Mekanik Özeliklerinde Polivinil Alkol (PVA) Liflerin Etkisi
Authors: UYGUNOĞLU Tayfun , TOPÇU İlker Bekir , ŞİMŞEK Barış , ERYEŞİL Özge , AL-TURKİ Yaser Ahmad Yahya Ali
Published: August 2020

Betonarme yapılarda karşılaşılan en önemli sorun betonun gevrek davranışa sahip olmasıdır. Gevrek davranışa sahip yapı elemanları yükler altında hızlı bir şekilde plastik deformasyona uğrarlar. Gevrek davranışa sahip yapı elemanının sönümlediği enerji az olduğundan, yapı elemanı taşıma kapasitesine ulaştığı anda göçme meydana gelir. Bu nedenle yapı elemanlarının belirli bir oranda sünek davranışa sahip olmaları istenir. Betona katılan çeşitli lifler betona bir miktar süneklik kazandırarak betonun bu gevrek davranışınının sönümlediği enerjiden daha fazla enerji sönümleyebilmektedir. Bu çalışmada sunulan, farklı hacim fraksiyonlarında polivinil alkol (PVA) lifin, sertleşmiş harç özeliklerine etkileri araştırılmıştır. Lifler harç içine hacimce %2, %4, %6, oranlarında katılarak üretilmiş, bunun yanı sıra lif katkısız kontrol numunesi üretilmiştir. Üretilen numuneler sertleşmiş basınç ve eğilme dayanımı, ultrases hızı, su emme, dinamik elastisite modülü ve mikroyapı incelemesi testlerine tabi tutulmuş ve karşılaştırması yapılmıştır. Elde edilen sonuçlara göre, harçlarda PVA lif kullanım oranının artması çoklu çatlak davranışına sebep olarak sünek davranış sağlanmış bununla birlikte çatlak genişlikleri azalmıştır.
Internalizing a Discourse: Reading Shauna Singh Baldwin’s What the Body Remembers
Authors: Kaur Brahmjot
Published: August 2020

Shauna Singh Baldwin’s novel What the Body Remembers is mostly remembered as a Partition novel. No doubt, one of the best Partition novels, the novel is also successful in exemplifying how grand-narratives bring us into adherence and train our minds to pass on the same to our coming generations. Baldwin’s characters are prisoners to these grand-narratives but they hardly realize that, and thereby make no effort to shirk away from these beliefs. This paper endeavors to study these characters in the light of this socializing process, and the transformation that it brings.
THE EFFECTIVENESS OF KNOW-WANTLEARNED (KWL) STRATEGY IN IMPROVING READING COMPREHENSION OF THE EIGHT GRADE STUDENTS OF SMP NEGERI 14 PALU
Authors: Syafi’i Moh , Nurdin Nurdin , Fitriningsih Fitriningsih
Published: August 2020

The problem focus of this research is to improve students reading comprehension by using Know-Want-Learned (KWL), to make the students comprehend the text, And how the students make their own conclusion about the text. The object of this research was the eighth grade students of SMP Negeri 14 Palu that were divided into two group that was controlled group and experimental group. The aim was to know their improvement after the treatment of KnowWant-Learned (KWL) technique. This research was quantitative research, and the procedure of collected the data were observation, interview, Pre test, treatment, and Post Test. The data analysis used statistical analysis that was descriptive analysis. Statistical analysis is used to test the hypothesis. And the formula used to test the hypothesis was t-test with the level of significance 0,05. The result showed that the application of Know-Want-Learned (KWL) strategy was successful in improving students’ reading comprehension. It can be proven with the result oftest of significance (t-test) was 0,2496. It means the result of t-test is more than level of significance (0,05). Based on the conclusion above, suggested to the teacher especially English teacher is to use Know-Want-Learned (KWL) strategy or find out the other method to make thestudents interest to the material.
Implementasi Kebijakan Pengembangan Kawasan EKonomi Khusus Tanjung Kelayang
Authors: Chaniago Alvin Rizalsan , Juwono Vishnu
Published: August 2020

Tanjung Kelayang, as a tourism SEZ (Special Economic Zone), has some difficulties with land disputes and unfulfilled investment targets. This paper attempts to study the implementation with streams/critical juncture approach and rational implementation model. This study was conducted with a post-positivist approach and data collection by conducting in-depth interviews and literature studies as secondary data. The study showed that the SEZ was BUPP innovation to develop bussiness with incentives from the government. The government sees this as an opportunity to increase community development. The implementation of the policy was carried out with lots of actors from the government and BUPP. The problem with investment in SEZ is that the investors choose to wait and see. In terms of the important factor that influenced the implementation are unclear vision and mission, unfulfilled investment target, and monitoring without the ability to intervene..

Keywords: Special Economic Zone; Tourism; Implementation; Policy

Abstrak

KEK Tanjung Kelayang yang merupakan KEK pariwisata memiliki beberapa kendala, seperti konflik sengketa tanah dan tidak tercapainya target investasi. Tulisan ini mencoba menganalisis implementasi dari Kebijkan KEK Tanjung Kelayang tersebut dengan menggunakan multiple streams/critical juncture approach dan model implementasi rasional. Penelitian menggunakan pendekatan post-positivist dan dilakukan pengumpulan data dengan melakukan wawancara mendalam serta data sekunder dari literatur. Hasil penelitian ini menunjukan bahwa KEK merupakan inisiatif BUPP untuk mengembangkan kawasan dengan insentif dari pemerintah. Pemerintah ikut serta melihat potensi dari pengembangan kawasannya dapat meningkatkan perekonomian masyarakat. Dalam implementasi kebijakan dilakukan oleh banyak aktor-aktor yang terdiri dari pemerintah dan BUPP. Masalah yang menjadi hambatan KEK adalah lambatnya realisasi investasi karena banyak investor yang wait and see. Karena faktor-faktor penting implementasi yang menghambat ada pada indikator visi, misi yang kurang jelas, perencanaan target investasi yang kurang dan pengawasan tanpa kemampuan intervensi.

Kata Kunci: Kawasan Ekonomi Khusus; Pariwisata; Implementasi; Kebijakan
Updated clinical evidence and place in therapy of bempedoic acid for hypercholesterolemia: ANMCO position paper
Authors: Colivicchi Furio , Di Fusco Stefania Angela , Scicchitano Pietro , Caldarola Pasquale , Murrone Adriano , Valente Serafina , Urbinati Stefano , Roncon Loris , Amodeo Vincenzo , Aspromonte Nadia , Cipriani Manlio , Domenicucci Stefano , Francese Giuseppina Maura , Imazio Massimo , Scotto di Uccio Fortunato , Di Lenarda Andrea , Gulizia Michele Massimo , Gabrielli Domenico
Published: August 2020

The central role of high low-density lipoprotein cholesterol levels in atherosclerotic cardiovascular disease has led to research focused on lipid-lowering agents for cardiovascular risk reduction. Bempedoic acid is an emerging treatment for hypercholesterolemia that has recently been approved for marketing in the United States and Europe. This review focuses on its mechanism of action and summarizes the main preclinical study findings. Furthermore, we report the clinical evidence supporting and guiding its use in hypercholesterolemia management.
SIMULASI SUMUR RESAPAN BERDASARKAN ANALISIS PERBANDINGAN KETINGGIAN AIR BANJIR DI KELAPA GADING JAKARTA
Authors: Felix Lionel , Sentosa Gregorius Sandjaja
Published: August 2020

Flooding has been a problem for the past few decades in Jakarta. The flooding in early January 2020 was one of the worst floods since 2013. One of the most severely affected areas was Kelapa Gading. To find a solution, infiltration wells are used. Infiltration well is a simple conservation in the form of a container that is built in the soil that functions to accommodate, hold and absorb surface water into the soil to increase the amount and position of the ground water level. The analysis begins by calculating the rainfall intensity from the January 2020 rainfall data, proceeding with the calculation of rainwater discharge with USSCS rational method, and calculation of the volume of water entering and not entering the drainage channel. This analysis focuses on flood water levels due to extreme rainfall, to then design infiltration wells. Analysis using the program is done after getting the results of manual calculations. The results of this analysis conclude that millions of infiltration wells are needed to absorb entire volume of flood water. This is due to the shallow groundwater and extreme conditions of rainfall.  Banjir sudah menjadi masalah selama beberapa dekade terakhir di Jakarta. Banjir pada awal Januari 2020 adalah salah satu banjir terparah sejak tahun 2013. Salah satu daerah yang paling terdampak adalah Kelapa Gading. Untuk mencari solusi banjir, digunakan sumur resapan. Sumur resapan adalah konservasi sederhana berupa wadah yang dibangun ke dalam tanah yang berfungsi menampung, menahan dan meresapkan air ke dalam tanah untuk meningkatkan muka air tanah. Analisis dimulai dengan menghitung intensitas hujan dari data curah hujan Januari 2020, lalu dilanjutkan dengan perhitungan debit air hujan dengan metode rasional USSCS, dan perhitungan volume air yang masuk dan tidak masuk ke saluran drainase. Analisis ini berfokus pada ketinggian air banjir akibat curah hujan yang ekstrim, untuk kemudian mendesain sumur resapan. Analisis menggunakan program dilakukan setelah mendapatkan hasil dari perhitungan manual. Hasil analisis ini menyimpulkan bahwa dibutuhkan jutaan sumur resapan untuk menyerap seluruh volume air banjir. Hal ini dikarenakan kondisi muka air tanah yang dangkal dan tingginya curah hujan.
ANALISIS ULANG STABILITAS TANAH DENGAN COMPACTED LATERITIC SOIL COLUMNS PADA COLLAPSIBLE SOIL MENGGUNAKAN RUMUS ELASTIK
Authors: Kusuma Antonius Kristanto , Sandjaja Gregorius
Published: August 2020

ABSTRACTIndonesia is a tropical country that has very high rainfall rate in the whole year. This is very difficult to overcome with land problems that exist in Indonesia. The condition of the land which has a very not  stable soil or we can say that it has collapsible status. Land that has collapse problems is prone to landslides, which involves very low soil carrying capacity and also very high water content in the soil. Many methods can be used to reduce collapsible soi lrate. In this re-analysis we calculate the problem of soil using the lateritic compacted soil columns. This process uses the formation of soil columns by compressing a number of points with a certain diameter so that the carrying capacity of the soil in order to repair and improve minimum occurrence of collapsible soil. But this method has advantages and disadvantages. From the results of the re-analysis conducted it was proven that the stability method using Compacted Lateritic Soil Colums reduced the possibility of soil experiencing collapsible soil. The analysis shows that the value of the edge of displacement or the total decreases due to the stability used using Compacted Lateritic Soil Colums. ABSTRAK  Indonesia adalah negara tropis yang memiliki curah hujan yang sangat tinggi. Hal tersebut sangat berpengaruh dengan keadaan stabilitas tanah yang berada di Indonesia. Keadaan  tanah yang memiliki stabilitas yang sangat tidak stabil dapat juga di sebut tanah dengan keadaan status collapsible . Tanah yang memiliki keadaan collapsible  memiliki  rentan mengalami longsor ., di akibatkan daya dukung tanah yang sangat rendah dan juga kadar air yang sangat tinggi di dalam kandungan tanah. Banyak metode stabilitas yang dapat dilakukan untuk mengurangi kemungkinan terjadinya collapsible soil. Pada analisis ulang perhitunga ini membahas stabilitas tanah menggunakanan Compacted Lateritic Soil Colums.Proses stabilitas ini menggunakan cara pebentukan kolom tanah dengan memadatkan bebarapa titik dengan diameter tertentu agar daya dukung tanah mengalami peningkatan dan mencegah terjadinya collapsible soil. Tetapi metode ini memiliki kelebihan dan juga kekurangan. Dari hasil analisi ulang yang dilakukan terbukti bahwa metode stabilitas menggunakan Compacted Lateritic Soil Colums mengurangi kemungkinan terjadinya tanah mengalami Collapsible soil. Dalam Analisis terlihat nilai edge of displacement atau total penurunan yang terjadi berkurang diakibatkan stabilitas yang di gunakan menggunakan Compacted Lateritic Soil Colums.
PRODUKTIVITAS PEKERJA DALAM PEKERJAAN PEMASANGAN DINDING BATA DENGAN METODE CREW BALANCE CHART
Authors: Putra Eddy , Sulistio Hendrik
Published: August 2020

The determination of the magnitude of value of productivity is the first step that must be conducted to determine magnitude of increase productivity that can be applied in construction projects. The determination of value of productivity requires the completeness of data obtained from workers data collection. Data collection displayed in form of Crew Balance Chart to get unproductive time and coefficient of workers based on field conditions in the installation of brick and to increase the productivity of workers on construction project of Residential Houses Cempaka Baru. Methods of data collection using observations in the field, as well as the data processed by using simple math. From the results of the research known to time is unproductive time of workers on the job installation of brick wall construction projects Cempaka Baru on front area is 9,711%, and on back area is 48,737% so it can be called that workers in the front area is quite productive while the workers in back area tend to be not productive. The productivity of workers front area amounted to 0,98 m2/h while productivity in ideal conditions can reach 1,33 m2/h, while that for back area the productivity 1,53 m2/h while productivity ideally 2,25 m2/h.ABSTRAKPenentuan besarnya nilai produktivitas merupakan langkah awal yang harus dilakukan untuk mengetahui besarnya peningkatan produktivitas yang dapat diterapkan dalam proyek konstruksi. Penentuan nilai produktivitas memerlukan kelengkapan data yang didapat dari pendataan pekerja. Pendataan pekerja ini ditampilkan dalam bentuk diagram Crew Balance Chart untuk mendapatkan waktu tidak produktif dan koefisien pekerja berdasarkan kondisi lapangan dalam pekerjaan pemasangan dinding bata serta dapat meningkatan produktivitas pekerja pada proyek konstruksi Rumah Tinggal Cempaka Baru. Metode pengumpulan data dalam crew balance chart menggunakan observasi di lapangan, serta data diolah dengan menggunakan matematika sederhana. Dari hasil penelitian diketahui waktu tidak produktif pekerja pada pekerjaan pemasangan dinding bata proyek konstruksi Cempaka Baru pada area depan 9,711% dan pada area belakang 48,737% sehingga dapat dapat disebut pekerja pada area depan cukup produktif sementara pekerja pada area belakang cenderung tidak produktif. Produktivitas pekerja pada area depan sebesar 0,98 m2/jam sedangkan produktivitas dalam kondisi ideal dapat mencapai 1,33 m2/jam, sementara itu untuk area belakang produktivitasnya sebesar 1,53 m2/jam sedangkan produktivitas idealnya 2,25 m2/jam.
ANALISIS PENJADWALAN PROYEK GEDUNG BERTINGKAT DENGAN METODE PERT DAN M-PERT MENGGUNAKAN SIMULASI MONTE CARLO
Authors: Putra Josua Guntur , Sekarsari Jane
Published: August 2020

One of the keys to success in construction execution is timeliness. In fact, construction is often late than originally planned. It’s caused by project scheduling uncertainty. Deterministic scheduling methods use data from previous projects to determine work duration. However, not every project has same work duration. The PERT method provides a probabilistic approach that can overcome these uncertainties, but it doesn’t account for the increase in duration due to parallel activities. In 2017, the PERT method was developed into the M-PERT method. The purpose of this study is to compare the mean duration and standard deviation of the overall project between PERT and M-PERT methods and compare them in Monte Carlo simulation. The research method used is to calculate the mean duration of the project with the PERT, M-PERT, and Monte Carlo simulation. The study was applied to a three-story building project. From the results of the study, the standard deviation obtained was 5.079 for the M-PERT method, 8.915 for the PERT method, and 5.25 for the Monte Carlo simulation. These results show the M-PERT method can provide closer results to computer simulation result than the PERT method. Small standard deviation value indicates the M-PERT method gives more accurate results.ABSTRAKSalah satu kunci keberhasilan dalam suatu pelaksanaan konstruksi adalah ketepatan waktu. Kenyataannya, pelaksanaan konstruksi sering mengalami keterlambatan waktu dari yang direncanakan. Hal ini disebabkan oleh ketidakpastian dalam merencanakan penjadwalan proyek. Metode penjadwalan yang bersifat deterministik menggunakan data dari proyek sebelumnya untuk menentukan durasi pekerjaan. Akan tetapi, tidak setiap proyek memiliki durasi pekerjaan yang sama. Metode PERT memberikan pendekatan probabilistik yang dapat mengatasi ketidakpastian tersebut, tetapi metode ini tidak memperhitungkan pertambahan durasi akibat adanya kegiatan yang berbentuk paralel. Pada tahun 2017, metode PERT dikembangkan menjadi metode M-PERT. Tujuan dari penelitian ini adalah membandingkan mean durasi dan standar deviasi proyek secara keseluruhan antara metode PERT dan M-PERT dan membandingkan kedua metode tersebut dalam simulasi Monte Carlo. Metode penelitian yang dilakukan adalah menghitung mean durasi proyek dengan metode PERT, M-PERT, dan simulasi Monte Carlo. Penelitian diterapkan pada proyek gedung bertingkat tiga. Dari hasil penelitian, nilai standar deviasi diperoleh sebesar 5,079 untuk metode M-PERT, 8,915 untuk metode PERT, dan 5,25 untuk simulasi Monte Carlo. Hasil ini menunjukan metode M-PERT dapat memberikan hasil yang lebih mendekati hasil simulasi komputer daripada metode PERT. Nilai standar deviasi yang kecil menunjukan metode M-PERT memberikan hasil yang lebih akurat.
ANALISIS TINGKAT KETEPATAN WAKTU KRL COMMUTER LINE LINTAS TANAH ABANG-RANGKASBITUNG (STUDI KASUS: STASIUN CISAUK)
Authors: Bintang Giovanni , Linggasari Dewi , Angkat Hokbyan
Published: August 2020

Commuter Line trains are one of the modes of transportation that are very popular with the Jabodetabek community. KRL Commuter Line is capable of reducing the level of congestion in urban areas, so it is expected that the KRL Commuter Line is able to meet the needs of the community with punctuality in performance. This study’s purpose is to identify the timeliness of Green Line KRL departures by scheduling it and classify the level of Green Line KRL departure delays and determine solutions that can be applied to reduce the level of KRL Green Line departure. The research method used to collect data by online surveys and field studies. Then analyzed with Gap Analysis in order to obtain information about individual characteristics, characteristics of travel, and perceived delays according to KRL Green Line users. From the results of the analysis, it was found that KRL users have 3 late tolerance limits according to the Ministerial Regulation set a delay tolerance limit of 5 minutes while the results of the perception of KRL users on the Green Line lane tolerance limit of 5 minutes and finally according to KRL users at Cisauk Station tolerate delays by 10 minutes.  ABSTRAKKereta Commuter Line adalah salah satu moda transportasi yang sangat diminati masyarakat Jabodetabek. KRL Commuter Line juga dinilai mampu mengurangi tingkat kemacetan di perkotaan, sehingga diharapkan KRL Commuter Line mampu memenuhi kebutuhan masyarakat dengan ketepatan waktu dalam kinerjanya. Tujuan penelitian ini adalah untuk mengindentifikasi ketepatan waktu keberangkatan KRL Green Line dengan penjadwalannya serta mengklasifikasikan tingkat keterlambatan keberangkatan KRL Green Line dan menentukan solusi yang dapat diterapkan untuk mengurangi tingkat keterlambatan keberangkatan KRL Green Line. Metode Penelitian yang digunakan untuk mengumpulkan data adalah dengan survey online dan studi lapangan. Lalu dianalisis dengan Gap Analysis agar didapatkan informasi mengenai karateristik individu, karateristik perjalanan, dan persepsi keterlambatan menurut pengguna  KRL Green Line. Dari hasil analisis, didapat bahwa pengguna KRL mempunyai 3 batasan toleransi keterlambatan yaitu menurut Peraturan Menteri ditetapkan batas toleransi keterlambatan sebesar 5 menit sedangkan hasil dari persepsi pengguna KRL jalur Green Line batas toleransi keterlambatan sebesar 5 menit dan yang terakhir menurut pengguna KRL di Stasiun Cisauk menoleransikan keterlambatan sebesar 10 menit.
Sistem Pengendali Smart-Kontak dengan Aplikasi Android dan Web
Authors: Suraidi Suraidi , Nathania Shinta
Published: August 2020

Smart-kontak is a portable power outlet that can be controlled remotely by using Android application and website. Android application can run smart-kontak through Bluetooth, whereas website can manage smart-kontak through Wi-Fi. Both Android application and website can control the power button of the smart-kontak, however there is an additional feature on the website as a timer setting which will set how long the smart-kontak be on. The on/off status and remaining time of the smart-kontak can be seen on Android application and website. Its system design uses microcontroller LOLIN D32 as processing module and Arduino Software (IDE) to write the program. Android application is designed by using Android Studio Software while the website is written with HTML. System testing is done by controlling the smart-kontak through Android application and website. The testing shows that smart-kontak can be run through Android application and website according to the program and all modules function well.ABSTRAK: Smart-kontak merupakan stopkontak portable yang dapat dikendalikan dari jarak jauh dengan menggunakan aplikasi Android dan situs web. Aplikasi Android dapat mengendalikan smart-kontak melalui Bluetooth, sedangkan situs web dapat mengendalikan smart-kontak melalui Wi-Fi. Aplikasi Android dan situs web dapat mengatur on/off dari smart-kontak, namun pada situs web terdapat fitur tambahan berupa timer untuk mengatur lamanya smart-kontak menyala. Status on/off dan remaining time dari smart-kontak dapat dilihat pada Aplikasi Android dan situs web. Perancangan sistem ini menggunakan mikrokontroler LOLIN D32 sebagai modul pemrosesnya dan Arduino Software (IDE) untuk menulis program. Aplikasi Android dirancang menggunakan software Android Studio sedangkan situs web ditulis menggunakan HTML. Pengujian sistem ini dilakukan dengan mengendalikan smart-kontak melalui aplikasi Android dan situs web. Pengujian sistem menunjukkan bahwa smart-kontak dapat dikendalikan melalui aplikasi Android dan situs web sesuai dengan program yang dibuat dan semua modul berfungsi sesuai dengan baik
TRAFFIC LIGHT SYSTEMS MENGGUNAKAN VISIBLE LIGHT COMMUNICATION (VLC) SEBAGAI ALAT BANTU TUNANETRA UNTUK MENYEBERANG JALAN
Authors: Darlis Arsyad Ramadhan , Adrian Dean
Published: August 2020

The people with visual impairment have problems in mobility and orientation, especially in the outdoor environment. Recently, traffic lights systems, which is a facility where someone crosses do not support visually implaired people so they still need help from others in crossing the road. In this study, a system that integrates traffic lights is implemented using Visible Light Communication (VLC) technology, where the VLC transmitter is mounted on a traffic light, and the VLC receiver is installed as a wearable device that can be used with the audio information signal. The measurement  is done by considering the use of color filters. The measurement results show that the transmitter system has been able to send signals with audio frequencies from 300 Hz to 4000 Hz. Besides that, receiving an information signal consisting of a audio signal from a transmitter mounted on a traffic light with a red, yellow and green color filter can be received by a VLC receiver that is placed on a visually impaired person of good quality with the signal voltage received above 4 Vpp, where the use of a yellow filter shows the best signal reception results with a voltage output of 5.00 Vpp at a frequency of 2400 Hz compared to other color filters.ABSTRAK: Penyandang tuna netra memiliki masalah dalam hal mobilitas dan orientasi, khususnya di lingkungan luar (outdoor). Pada sistem yang terdapat pada lampu lalu lintas (traffic light) yang merupakan fasilitas dimana seseorang menyebrang saat ini belum mendukung penyandang tuna netra, sehingga sampai saat ini masih membutuhkan bantuan orang lain dalam menyebrang jalan. Pada penelitian ini, sebuah sistem yang diintegrasikan pada lampu lalu lintas diimplementasikan menggunakan teknologi Visible Light Communication (VLC), dimana VLC transmitter dipasang pada lampu lalu lintas dan VLC receiver dipasang sebagai wearable device dengan sinyal informasi suara digunakan oleh penyandang tunanetra sehingga dapat menerima informasi mengenai kondisi lampu lalu lintas pada saat itu. Pengujian sistem dilakukan dengan mempertimbangkan penggunaan filter berwarna. Hasil pengukuran menunjukan bahwa sistem transmitter telah dapat mengirimkan sinyal dengan frekuensi suara dari 300 Hz sampai 4000 Hz. Disamping itu, penerimaan sinyal informasi berupa sinyal suara dari transmitter yang terpasang pada lampu lalu lintas dengan filter warna Merah, Kuning dan Hijau  telah dapat diterima oleh receiver yang ditempatkan pada penyandang tuna netra dengan kualitas baik dengan tegangan sinyal yang diterima diatas 4 Vpp, dimana penggunaan filter warna kuning menunjukan hasil penerimaan sinyal yang paling baik dengan tegangan output 5,00 Vpp pada frekuensi 2400 Hz dibandingkan dibandingkan penggunaan filter warna lainnya
A resistência popular ao ideário da elite intelectual
Authors: Rocha Julia Siqueira , Escobar Tatiana Pires , Valle Ione Ribeiro
Published: August 2020

Este artigo analisa, a partir da história presente, o retrocesso que o campo educacional vem sofrendo no Brasil com a ascensão da extrema-direita à presidência da República. Em especial, com a propagação da ideologia excludente que se instalou no Ministério da Educação. Trata-se de análise sociológica sobre a tentativa de apagamento dos incipientes avanços conquistados nas últimas décadas, principalmente no Ensino Superior, por parcela significativa da população cuja origem de nascimento se situa nas camadas de baixa renda. Analisamos o discurso ultraconservador e obscurantista do ministro da Educação, que desassocia mérito de oportunidades, o que revela o projeto elitista e antidemocrático em vigor.
SOUTHEAST ASIA REGIONAL COOPERATION ON TACKLING MARINE PLASTIC LITTER
Authors: Sabatira Febryani
Published: August 2020

The sea covers 70% of the earth and is the source of livelihood for people all over the world.  It is estimated that each year 6-12 million tons of plastic are dumped into the ocean. In the Southeast Asian region, the concentration of marine plastic litter in the ocean has reached a severe level. Six out of the 10 ASEAN countries are listed on the Top 20 of countries ranked by mass of the mismanaged plastic waste. Various legal instruments and supporting programs have been developed. However, the existence of these instruments and programs have not had a significant impact on combating marine plastic litter. This study aims to find out how a regional community can conquer the severe pollution of our oceans. This research uses normative legal analysis with secondary data sources and literature study techniques. The result of the research showed ASEAN initiated the regional cooperation amongst southeast Asia states in combating marine plastic litters as the competent regional organisation that carried out through institutional frameworks and subsidiary working groups, which have enacted two regional soft-law instruments, namely the Bangkok Declaration on Marine Debris and the ASEAN Framework for Action on Marine Debris.