bluuebunny/crossref_metadata_2025 huggingface dataset:
Ocena wpływu krioterapii miejscowej na stan funkcjonalny rąk u kobiet z reumatoidalnym zapaleniem stawów
Authors:   Klinika Chorób Wewnętrznych, Rehabilitacji i Medycyny Fizykalnej Uniwersytetu Medycz- nego w Łodzi, Przedborska Agnieszka , Kilon Małgorzata ,   Klinika Chorób Wewnętrznych, Rehabilitacji i Medycyny Fizykalnej Uniwersytetu Medycz- nego w Łodzi, Kikowski Łukasz ,   Zakład Alergologii i Rehabilitacji Oddechowej Uniwersytetu Medycznego w Łodzi, Pomorska Ewa ,   Klinika Reumatologii Uniwersytetu Medycznego w Łodzi, Raczkowski Jan ,   Klinika Rehabilitacji Ortopedycznej i Pourazowej Uniwersytetu Medycznego w Łodzi
Published: January 2024

Introduction: Rheumatoid arthritis (RA) causes lesions in the joints of the hands in 90% of cases. They cause pain and affect the formation of deformities and reduce manual dexterity. The aim of the study was to assess the effect of local cryotherapy on the functional state of the hands in women with rheumatoid arthritis. Material and methods: The study included 45 women diagnosed with RA, who underwent 10 sessions of local cryotherapy in the area of both hands. The mean age in the study group was 58.7 ± 9.2 years. The effectiveness of the therapy was assessed on the basis of: pain intensity according to the VAS scale, duration of morning stiffness and examination of the functional state of hands according to the FIHOA scale. JAMAR hydraulic dynamometer was used to measure the grip strength. The data were analyzed statistically. Results: After the therapy, a statistically significant (p <0.0001) reduction of the duration of morning stiffness was observed (before and after treatment – Me (IQR) respectively: 20 (10–60) minutes vs. 10 (1–30) minutes); reduction of pain according to the VAS scale (before and after therapy – Me (IQR) respectively: 5 (4–7) scores vs. 3 (1–4) scores). The functional state of hands improved significantly according to the FIHOA scale (before and after treatment – Me (IQR) respectively: 6 (1–12) scores vs. 1 (0–6) scores) as well as the muscle strength of the right hand (before and after treatment mean ± SD: 6.6 ± 2.5 kg vs. 8.1 ± 3.1 kg) and left hand (6.5 ± 2.2 kg vs. 7.7 ± 2.8 kg). Conclusions: The use of local cryotherapy as a method of physical therapy is an effective component in the comprehensive treatment of RA. Cryotherapy significantly improves the functional state of hands, allows to increase muscle strength and reduce pain, which ensures independence in everyday activities.
Zastosowanie autorskiego modelu planowania indywidualnego programu i technologii fizjoterapii osób z zaburzeniami układu oddechowego w szkoleniu fizjoterapeutów
Authors:   Lwowski Narodowy Uniwersytet Medycyny Weterynaryjnej i Biotechnologii im. S.Z. Gżyckiego, Ivasyk Nataliya
Published: January 2024

Introduction: The aim of the study was to determine the expediency of applying the author’s model of planning an individual program and technology of physical therapy for persons with respiratory disorders for physical therapists. Material and methods: methods of individual expert assessments. 24 undergraduate students after completing the profile discipline and after completing clinical practice in the departments of pulmonology and allergology. Results: Our proposed technology of physical therapy of persons with dysfunction of the respiratory system in the hospital combines two interrelated components: a program containing a sequence of stages of the process (procedure) with the definition of its main components (operations), and the principle of selection of intervention methods to the symptoms of the disease, taking into account their characteristics, causes and mechanisms of dysfunction in the person with this disease (activity). The developed model of planning an individual program of physical therapy for persons with respiratory disorders is a complex formation consisting of five interrelated functional subsystems: clinical and functional patient data (data from medical history and examination); identification of problems (rehabilitation diagnosis); setting goals and objectives; selection of means; component of the activity. Conclusions: The proposed model of planning an individual program and technology of physical therapy for people with respiratory disorders contributes to a better perception of the training material on the individual program of physical therapy for people with bronchopulmonary diseases both in practical training and during clinical practice in specialized departments, which indicates the feasibility of its use in the educational process of students.
Czynniki różnicujące równowagę dzieci w wieku szkolnym
Authors:   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rze- szów, Polska, Baran Rafał , Kozioł Kinga ,   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rze- szów, Polska, Baran Joanna ,   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rze- szów, Polska, Leszczak Justyna ,   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rze- szów, Polska, Pop Teresa ,   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rze- szów, Polska
Published: January 2024

Introduction: Balance has a very significant impact on the level of functioning in society. This is a trait that can be shaped throughout your life, however, it develops most dynamically during childhood. Balance measurements can be made using specialized devices, most often connected to a computer system. This is not the only way, because body balance can be measured by performing equivalent tests. Several of them have been used to conduct research in this work. The aim of the work was to present the influence of body composition on the balance. The studies were also to check the relationship between balance and gender, age, height and weight. Material and method: Group of 64 girls and 50 boys aged 7–10 were examined. The body mass composition was measured using the Tanita MC 980 MA analyzer. Balance was measured using the 2-weight test, standing on one lower limb with open and closed eyes (time measured with a stopwatch), jumping on one leg of the lower leg with open and closed eyes (time measured with a stopwatch). Result: The research showed significant correlations between growth, age, weight and balance parameters. Higher values of the given factors had a positive effect on the balance. Girls were influenced most by age, and boys by height. Statistical analysis did not present significant correlations between balance parameters and body mass composition. With reference to the symmetry of loading of the lower limbs, no significant correlations were detected with the aforementioned factors. Conclusion: The balance of children depends on sex and age; female and elderly people have a better balance. People with higher fat content in the body show a worse balance; people with a higher content of lean tissue and water have better equivalent properties. Better symmetry of the load was achieved by older people, with a larger body mass and taller people; gender has no effect on the symmetry of loading of the lower limbs. Higher content of adipose tissue has a positive effect on the symmetry of loading the lower limbs.
Recent advances in computational drug discovery for therapy against coronavirus SARS-CoV-2
Authors: Ivanov Volodymyr , Lohachova Kateryna , Kolesnik Yaroslav , Zakharov Anton , Yevsieieva Larysa , Kyrychenko Alexander , Langer Thierry , Kovalenko Sergiy M. , Kalugin Oleg N.
Published: January 2024

Despite essential experimental efforts focused on studying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), computational chemistry methods are promising complementary tools in combating coronavirus disease 2019 (COVID-19). The present review aims to provide readers with the recent progress and advances in computational approaches currently used to streamline drug discovery and development in the context of COVID-19. Our review is dual purpose. It is intended (a) to familiarize the readership with the general concept of QSAR, in silico screening, molecular docking and molecular dynamics (MD) simulations and (b) to provide key examples of the recent applications of these computational tools in discovering novel therapeutic agents against COVID-19. We outline how structure- and ligand-based drug design can accelerate the structural elucidation of pharmacological drug targeting and the discovery of preclinical drug candidate molecules. Several examples of MD computational studies demonstrate how atomistic MD simulations can facilitate our understanding of the molecular basis of drug actions and biological mechanisms of virus inhibition in atomic detail. Finally, the short- and long-term perspectives in computational drug discovery are discussed.
The aim of this study is to summarize the last three years' progress and advances in computational approaches currently used to streamline the drug discovery and development process in the context of COVID-19.
Materials and methods. The literature overview of QSAR, in silico screening, machine learning, molecular docking and molecular dynamics (MD) simulations is given in the context of COVID-19. The literature search was performed using online databases, such as Scopus, Web of Science, PDB-protein databank, and PubMed, focusing on the following keywords - human coronavirus, QSAR, molecular docking, virtual screening, machine learning, molecular dynamics, Mpro and PLpro proteases, SARS-CоV-2, respectively.
Results. The review familiarizes the readership with the general concept of QSAR, in silico screening, machine learning, molecular docking and MD simulations and provides key examples of the recent applications of these computational tools in discovering novel therapeutic agents against COVID-19.
Conclusions. New insight into the recent progress and achievements in computer-guided drug discovery for therapeutic agents against SARS-CoV-2 is provided
Comparative analysis of essential oil containing raw materials of honeyherb (Lippia dulcis Trevir.) under different growing conditions
Authors: Marchyshyn Svitlana , Slobodianiuk Liudmyla , Budniak Liliia , Dakhym Iryna , Boyko Larysa , Kyryliv Mariia , Bekus Iryna
Published: January 2024

The use of plant raw materials is one of the areas of modern pharmaceutical science in the production of herbal drugs. In this regard, one of the oldest medicinal plants, Lippia dulcis Trevir (Phyla scaberrima (Juss. ex Pers.) Moldenke) from Verbenaceae family, is of great interest. According to traditional Mexican medicine, Lippia dulcis is used in the treatment of colds, coughs, bronchitis, and digestive disorders as an anti-inflammatory, antitussive, antipyretic, expectorant, emollient and diuretic agent.

The aim. The aim of our study was to identify and determine the quantitative content of essential oils by GC/MS method in Lippia dulcis herb shoots.

Materials and methods. The determination of the essential oil composition of Lippia dulcis was conducted using Agilent Technologies' 6890 chromatograph with mass spectrometric detector 5973 (Agilent Technologies, USA).

Results. The GC/MS method 19 components of essential oil were identified in L. dulcis shoots grown in open soil conditions, the total content of which was 1274.82 μg/g, in L. dulcis shoots grown in closed soil conditions - 23, the total content of which was 2361.11 μg/g. Thus, the total content of essential oil in shoots of L. dulcis grown in closed soil conditions was 1.8 times higher than in shoots of L. dulcis grown in open soil conditions.

Conclusions. The component composition of the essential oil of L. dulcis shoots harvested from plants grown in open soil conditions (LD-1) and closed soil conditions (LD-2) was investigated using the chromato-mass spectrometric method. The following pharmacologically important components - camphor, germacrene D, caryophyllene, α-bisabolene - were found in both samples of the essential oil of L. dulcis shoots in significant quantities, which indicates the prospects for further technological and pharmacological studies of honey herb raw materials
Design and validation of analytical methods for quantitative determination of active ingredients in extemporal combined medicine in spray form
Authors: Cherniakova Valeriia , Myhal Artem , Rudiuk Vitalii , Studenyak Yaroslav , Kryvanych Oleksandr , Bevz Nataliia , Georgiyants Victoriya
Published: January 2024

The aim of the work was the development and study of the validation characteristics of the method of quantitative determination of phenylephrine hydrochloride, nitrofural and diphenhydramine hydrochloride when they are simultaneously present in an extemporaneous combined medicinal product in the form of a spray using liquid chromatography method.
Materials and methods. Agilent 1260 liquid chromatographs, equipped with a diode-matrix and UV detector from the company "Agilent technologies", USA. Chromatographic columns 250×4.6 mm filled with octadecylsilyl silica gel for chromatography (Zorbax StableBond SB-Aq, Agilent company), mobile phase - 0.1 % aqueous solution of trifluoroacetic acid R - methanol R, elution mode - gradient; mobile phase speed – 1.2 ml/min; the detection wavelength is 220 nm.
Results. The determined chromatographic conditions ensure proper separation of the peaks of the substances to be determined: phenylephrine hydrochloride, nitrofural and diphenhydramine hydrochloride in their joint presence, and do not have a negative effect on the quantitative assessment of their content. Validation tests were conducted to confirm the suitability of the analytical method for the performance of the task - control of the quantitative content of active substances in the combined medicinal product in the form of a spray. The determined validation characteristics indicate that the method is characterized by appropriate specificity, linearity, correctness and convergence in the range of application for phenylephrine hydrochloride (range 0.499-0.749 mg/ml, ΔZ=0.44 ≤ max ΔZ=3.20, d=0.22 ≤ max d=1.02, a=0.01  max a=5.1, r = 0.9997  min r= 0.9924), nitrofural (range 0.154-0.231 mg/ml, ΔZ=0.44 ≤ max ΔZ=3.20, d=0.62 ≤ max d=1.02, a=0.0006  max a=5.1, r = 0.9996  min r= 0.9924) and diphenhydramine hydrochloride (range 0.499-0.749 mg/ml, ΔZ=0.50 ≤ max ΔZ=3.20, d=0.05 ≤ max d=1.02, a=0.076  max a=5.1, r = 0.9999  min r= 0.9924).
Conclusions. An analytical technique for the quantitative determination of phenylephrine hydrochloride, nitrofural and diphenhydramine hydrochloride when simultaneously present in an extemporaneous combined medicinal product in the form of a spray by the method of high-performance liquid chromatography was developed. The determined validation parameters confirm the correctness of the methodology. The proposed HPLC technique was used to study the chemical stability of the spray for the treatment of allergic rhinitis
Organizational and legal provision for supervision and control over compliance with labor law in Ukraine: international standards and national practice
Authors: Terela Halyna
Published: January 2024

The purpose of the article is to study the state and trends in the development of organizational and legal support for supervision and control of compliance with labor law in Ukraine through the prism of international standards. To achieve the goal there are defined the following tasks: to reveal the content and meaning of the concept for the integrated system of labor inspection; characterize the impact of international standards on the organizational and legal provision of supervision and control over compliance with labor law in Ukraine; determine the trends in the development of organizational and legal support for supervision and control in the field of labor. There were used general philosophical method of dialectics, systemic and structural-functional general scientific methods, hermeneutic, formal-legal and prognostic special-legal methods during the research. Their combination made it possible to investigate the content and purpose of the integrated approach to labor inspection, initiated and supported by the International Labor Organization. Such an approach covers occupational safety and hygiene, labor relations, working conditions, and provides for the formation of a complete system of labor inspection with the integration of its administrative, procedural and technical elements through simultaneous implementation of measures at the international, national (state), industry (sectoral) and production (local, operational) levels to increase the effectiveness of labor rights protection. The trends of the organizational and legal provision for supervision and control over compliance with the labor law in Ukraine were analyzed from the point of view of the analysis for the legal instruments of the mentioned levels. Firstly, functional integration/concentration of functions in a single state labor inspection service. Secondly, coordination and consolidation of the efforts of the State Labor Service, state bodies that have joint tasks with the labor inspectorate, local self-government bodies, and social partners. Thirdly, modernization of the national system of managing the safety of workers at work based on the principles of proactivity, prevention of industrial risks, and strengthening the role of the employer's internal control in ensuring proper, safe, and dignified working conditions. Fourthly, there is a tendency to expand the practice of combining surveillance (control) measures with preventive, informational, advisory, and analytical efforts
Experimental study of the properties of the base of a novel combined full laminar overdenture
Authors:   Academician E.A. Wagner Perm State Medical University of Ministry of Health of Russian Federation, Astashina Nataliya , Bazhin Alexey , Kachenyuk Maxim ,   Perm National Research Polytechnic University, Sergeeva Ekaterina ,   ALTEYDENT LLC, Kazakov Sergey ,   Academician E.A. Wagner Perm State Medical University of Ministry of Health of Russian Federation, Rogozhnikova Evgeniya , Baydarov Andrey ,   Academician E.A. Wagner Perm State Medical University of Ministry of Health of Russian Federation,   Perm National Research Polytechnic University, Nikitin Vladislav ,   Perm National Research Polytechnic University
Published: January 2024

This research is targeted at experimental study of the properties of the base of a newly-designed combined full laminar overdenture which is used in fully edentulous patients. The design is novel in that a framework (Bicon LLC, Boston, USA) made of a fibreglass-based composite (for example, Trinia). It is introduced into the base of a full laminar overdenture which is made of an acrylic resin. To substantiate performance of the proposed design and of subsequent modelling of biomechanical behaviour of the of the novel combined dental design, properties of the following base specimens were subjected to comparative study: 1 – poly(methyl methacrylate)-based acrylic resin; 2 – mesh-reinforced poly(methyl methacrylate)-based acrylic resin, Renfert (Germany); 3 – Trinia-framework poly(methyl methacrylate)-based acrylic resin. The experimental studies determined that, when combined with Trinia (Bicon LLC, Boston, USA), the base resin demonstrates excellent strength properties, considerably better than in the existing counterparts. Furthermore, metal mesh showed low performance when used to reinforce full laminar overdenture base. The findings will allow us to proceed with biomechanical modeling and to look into distribution patterns of functional loads which develop at the basal seat when a full laminar overdenture is used, and to determine optimum parameters for the structural components of the newly-designed combined full laminar overdenture.
Biomechanical modelling of the temporomandibular joint forces influence on the internal carotid artery
Authors:   Perm National Research Polytechnic  University, Tverier Victor , Shitoev Ivan , Nyashin Yuriy
Published: January 2024

Currently, cardiovascular diseases in many cases can cause premature death (more than 30% of deaths). In the literature, there are observations about the effect of the temporomandibular joint dysfunction on the state of the cervical portion of the internal carotid artery. Under the influence of the load in the joint, bends and, possibly, looping are formed in the artery, which lead to a decrease in the volume of cerebral circulation and the development of a stroke. To date, there is no strict description of the maxillofacial influence in general and the temporomandibular joint in particular on the brain nutrition, which for the most part goes through the internal carotid artery (up to 80% of the total blood volume). For the quantitative assessment of the loads influence on blood flow, the model example is considered, and it is shown the 34% decrease in the carotid artery opening due to forces in the temporomandibular joint. To confirm the hypothesis and explain the action of the effect of loads, it is necessary to develop the biomechanical model of the internal carotid artery and the temporomandibular joint interaction. This study is complicated by the variability of the living structures characteristics from person to person. In the article, it is provided the detailed description of this problem, proposed the formulation of the loading coupled problem on the branch of the carotid artery by forces in the joint and blood flow in this part of the artery and the algorithm for solving this problem through averaging and simpifying the model. The iterative procedure for interaction in the elasticity theory problems and the averaged blood flow problem are presented.
West-Wide Study to Identify Important Highway Locations for Wildlife Crossings
Authors: Paul Kylie , Faselt Jamie , Bell Matthew , Huijser Marcel P. , Theobald David , Keeley Annika , Ament Robert
Published: January 2024

Wildlife-vehicle collisions (WVCs), reduced ecological connectivity, and associated impacts to wildlife and humans are widespread problems across road networks, but mitigation measures like wildlife crossings1 that can address those problems are often considered expensive. This effort aims to support transportation agencies, wildlife agencies and other decision-makers by identifying important road segments where cost-effective wildlife crossings can be deployed to address motorist safety, ecological connectivity and other conservation values across the eleven U.S. western conterminous states of Arizona, California, Colorado, Idaho, Montana, Nevada, New Mexico, Oregon, Utah, Washington, and Wyoming.
Case report on prolonged kidney graft survival without immunosuppressive therapy after allogeneic hematopoietic stem cell transplantation
Authors: Shmarina N. V. , Borovkova N. V. , Stolyarevich E. S. , Vasilyeva V. A. , Storozhev R. V. , Dmitriev I. V. , Balkarov A. G. , Parovichnikova E. N.
Published: January 2024

Background. The possibility of inducing immunological tolerance in allogeneic organ transplant recipients is a research goal of the transplantology community, as it will ensure the likelihood of complete engraftment of a foreign organ. However, such a task presently remains difficult to accomplish.

Objective: to demonstrate longterm kidney graft survival without signs of acute rejection and without immunosuppressive therapy in a patient who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) from a haploidentical donor for post-transplant lymphoproliferative disorder (PTLD).

Methods and materials. Recipient’s graft function was assessed using clinical, laboratory, instrumental and pathomorphological examination methods.

Results. With no immunosuppressive therapy for more than four years, the kidney recipient showed stable, satisfactory graft function.

Conclusion. The described clinical case demonstrates the development of immunological tolerance to a kidney graft in a recipient of allogeneic hematopoietic stem cells (HSCs).
A case of successful orthotopic heart retransplantation in an 11-year-old child
Authors: Ivanov I. Yu. , Kalmykov V. S. , Grebennik V. K. , Ismail-zade I. K. , Ishmukhametov G. I. , Dyachenko Ya. A. , Maistrenko N. S. , Dzhum V. I. , Khatnyuk O. A.
Published: January 2024

Objective: to present a clinical case of an 11-year-old child who underwent repeat heart transplantation (HT) at Almazov National Medical Research Centre in St. Petersburg, Russia.

Materials and methods. A case of successful heart retransplantation in an 11-year-old child with cardiac allograft vasculopathy (CAV) is presented.

Results. The postoperative period after heart retransplantation had no significant differences with the postoperative period of primary heart recipients. The complexity of the intraoperative stage was determined by pronounced adhesions. As part of preoperative preparation, the patient underwent chest CT scan, which, in our experience, allows us to evaluate the heart syntopy and, in turn, is an important preparatory stage in planning repeat interventions.

Conclusion. Our first experience of cardiac retransplantation in pediatric patients suggests that repeat HT is the most optimal treatment for pediatric patients with CAV and requires more thorough preoperative preparation.
Social bases for the dialogue on deceased organ donation
Authors: Reznik O. N. , Reznik A. O.
Published: January 2024

This article assesses the changes in the coverage of the problem of organ donation in Russia. The boundaries of the dialogue on posthumous organ donation are outlined, taking into account the current organ donation model in Russia. The paper defines the concept of social capital, the sociology of organ donation and their significance for the development of deceased organ donation (DOD). Steps to promote the DOD concept in Russia are proposed.
Vascular complications after liver transplantation: contemporary approaches to detection and treatment. A literature review
Authors: Semash K. O. , Dzhanbekov T. A. , Akbarov M. M.
Published: January 2024

Vascular complications (VCs) after liver transplantation (LT) are rare but are one of the most dreaded conditions that can potentially lead to graft loss and recipient death. This paper has analyzed the international experience in the early diagnosis of various VCs that can develop following LT, as well as the optimal timing and methods of treatment of these complications.
A 5-year single-center experience in heart transplantation in Rostov oblast
Authors: Korobka V. L. , Kostrykin M. Yu. , Duzhikov A. A. , Shamkhanyants V. D. , Lobachev D. K. , Kotov O. V. , Kartashov A. A. , Sumin A. V. , Gusnay M. V. , Trapeznikova A. I. , Kudryashova E. A. , Korobka R. V.
Published: January 2024

Objective: to evaluate the outcomes of heart transplants performed at Rostov Regional Clinical Hospital within five years.

Materials and methods. Between 2017 and 2022, 29 orthotopic heart transplants (HT) were performed in our clinic. Heart failure was caused by postinfarction cardiosclerosis (21 cases, 72.4%) and dilated cardiomyopathy (8 cases, 27.6%). Among the recipients, 27 (93.1%) were men and 2 (6.9%) were women. Mean age was 53.14 ± 8.7 years (34 to 67 years). All patients received quadruple-drug immunosuppressive therapy, including induction with monoclonal antibodies; calcineurin inhibitor, mycophenolic acid, and corticosteroid were used after HT.

Results. In-hospital mortality was 10.34% (n = 3). The causes of death were multiple organ failure and infectious and septic complications. After discharge, 4 (13.8%) recipients died over 5 years. Rejection reaction with the development of graft dysfunction (3 recipients, 75%), infectious and septic complications (1 recipient, 25%) were the causes of death in the long-term period. The survival rate was analyzed according to the Kaplan–Meier estimate. One-year survival was 80.9%. Three-year survival rate corresponded to the 5-year survival rate – 70.56%. Five-year survival of patients surviving the first year after HT was 86.1%. Maximum follow-up period was 64 months.

Conclusion. HT continues to be the gold standard for patients with end-stage heart failure. Five-year HT experience in our center has shown a survival rate that is comparable to that of the International Society for Heart and Lung Transplantation (ISHLT).
How intentional are the employability strategies of Higher Education Institutions?
Authors: Sgobbi Francesca
Published: January 2024

An employability strategy communicates the commitment of higher education institutions (HEIs) towards students’ future, signals effectiveness and efficiency in resource allocation, and positions HEIs against competing institutions. However, not all HEIs display the same awareness when it comes to the design of a coherent bundle of actions in support of their graduates’ employability. This paper focuses on the formation of employment strategies to test the contrasting hypotheses of planned strategy, that frames strategy as an explicit and purposeful plan fully designed before deployment, and emergent strategy, where the adopted plan gradually unfolds from the interaction among different players and circumstances. Four case studies of Italian and Portuguese HEIs reveal emergent employability strategies that surpass the limitations set by modest intended employability targets. However, lack of guidance from an explicit action plan and limited resources may question the long-term viability of the emerging approaches.
Formação econômica do Brasil: uma obra-prima do estruturalismo cepalino
Authors: BIELSCHOWSKY RICARDO
Published: January 2024

RESUMO Formação Econômica do Brasil, de Celso Furtado, é o livro mais famoso da literatura econômica brasileira, desde sua primeira edição, há trinta anos. A essa altura, teve de imediato um impacto considerável nas ciências sociais brasileiras. Este artigo trata do contexto intelectual e ideológico brasileiro da década de 1950 e aponta os elementos “ecla-estruturalistas” da obra-prima de Furtado. A metodologia do livro, bem como seus aspectos analíticos, tem forte ligação com esse contexto.
Uma crítica à refutação lógica da macroeconomia neoclássica
Authors: SCHWARTSMAN ALEXANDRE , LOPES LUIZ FERNANDO ELEUTÉRIO , PESSÔA SAMUEL DE ABREU
Published: January 2024

RESUMO Este artigo é uma resposta ao artigo de Gilson Schwartz, publicado na Revista de Economia Política, vol. 9, n. 1. Mostra que sua pretendida refutação lógica da teoria macroeconômica neoclássica se deve a mal-entendidos conceituais. Demonstra esses mal-entendidos e sugere algumas formas mais razoáveis de crítica à macroeconomia neoclássica.
Percepção dos enfermeiros sobre o clima de segurança do paciente na atenção primária à saúde
Authors: Guirardello Edinêis de Brito , Jesus Mariana Véo Nery de , Vieira Lilian Ceroni , Oliveira Henrique Ceretta , Vergilio Maria Silvia Teixeira Giacomasso
Published: January 2024

Objetivo: avaliar o clima de segurança do paciente na Atenção Primária à Saúde, sob a perspectiva dos enfermeiros dos serviços. Método: estudo quantitativo e transversal, com 148 enfermeiros de um município do Estado de São Paulo. Foram utilizadas a versão brasileira do Primary Care Safety Questionnaire Survey e variáveis pessoais, profissionais e desempenho organizacional (intenção permanecer no trabalho, satisfação no trabalho, qualidade do cuidado e frequência de incidentes). Realizaram-se testes de comparação paramétricos, não paramétricos e coeficiente de correlação de Resultados: o clima de segurança foi positivo, com variação de 4,52 a 5,33; diferiu entre distritos para carga de trabalho (p=0,0214) e liderança (p=0,0129). As variáveis profissionais e dimensões do clima de segurança diferiram em relação à frequência de incidentes. Trabalho em equipe, sistema de segurança e aprendizagem foram fortemente correlacionados à satisfação no trabalho e moderadamente com percepção da qualidade do cuidado. Conclusão: trabalho em equipe e sistema de segurança e aprendizagem se destacaram pela correlação positiva com satisfação no trabalho e qualidade do cuidado. O clima de segurança positivo favorece o envolvimento dos enfermeiros da atenção primária para desenvolver planos de melhorias alinhados ao Programa Nacional de Segurança do Paciente.
Experiencia de hombres en el cuidado de un familiar con cáncer: una teoría fundamentada en los datos
Authors: Coppetti Larissa de Carli , Nietsche Elisabeta Albertina , Schimith Maria Denise , Radovanovic Cremilde Aparecida Trindade , Lacerda Maria Ribeiro , Girardon-Perlini Nara Marilene Oliveira
Published: January 2024

Objetivo: comprender el significado atribuido por los hombres a la experiencia de asistir a un familiar con cáncer y desarrollar una teoría sustantiva que represente la experiencia de los hombres acerca de dicho cuidado. Método: se trata de una investigación cualitativa guiada por el marco metodológico de la Teoría Fundamentada y los preceptos del Interaccionismo Simbólico. Se utilizó un formulario con datos de identificación y entrevista. El análisis siguió las etapas de codificación sustantiva y teórica. Resultados: participaron 12 hombres cuidadores de un familiar con cáncer. El constante análisis comparativo de los datos permitió elaborar una teoría sustantiva “Vivenciando el cuidado de un familiar con cáncer: el hombre como cuidador” explicando la experiencia que tiene como categoría central “El amor que impulsa el cuidado”, representando la acciones y actitudes simbólicas del hombre que vive en el contexto de enfermedad por cáncer y sus cuidados. Conclusión: la teoría permitió comprender los sentimientos, percepciones, formas de actuar y afrontar el diagnóstico, brindar cuidados, reconocer dificultades y aprender de las situaciones que se presentan, explicitando los procesos de interacción y elementos simbólicos presentes y cómo influyen en los hombres cuidadores en sus acciones y actitudes.
Vivência de homens no cuidado ao familiar com câncer: uma teoria fundamentada nos dados
Authors: Coppetti Larissa de Carli , Nietsche Elisabeta Albertina , Schimith Maria Denise , Radovanovic Cremilde Aparecida Trindade , Lacerda Maria Ribeiro , Girardon-Perlini Nara Marilene Oliveira
Published: January 2024

Objetivo: apreender o significado atribuído pelos homens à vivência do cuidado ao seu familiar com câncer e elaborar uma teoria substantiva que represente a vivência de homens no cuidado ao seu familiar com câncer. Método: trata-se de uma pesquisa qualitativa norteada pelo referencial metodológico da Teoria Fundamentado nos Dados e pelos preceitos do Interacionismo Simbólico. Utilizouse formulário com dados de identificação e entrevista. A análise seguiu as etapas de codificação substantiva e teórica. Resultados: participaram 12 homens cuidadores de seu familiar com câncer. A análise comparativa constante dos dados permitiu a elaboração de uma teoria substantiva “Vivenciando o cuidado de um familiar com câncer: o homem como cuidador” explicativa da vivência que tem como categoria central “O amor que conduz o cuidar”, representando as ações e atitudes simbólicas do homem ao viver no contexto do adoecimento por câncer e do cuidado. Conclusão: a teoria permitiu conhecer os sentimentos, percepções, modos de agir e enfrentar o diagnóstico, desempenhar o cuidado, reconhecer as dificuldades e aprender com as situações que se apresentam, deixando explícito os processos interacionais e os elementos simbólicos presentes e como estes influenciam os homens cuidadores em suas ações e atitudes.
Relação entre depressão, ansiedade, estresse e dependência de smartphone em estudantes de enfermagem na COVID-19
Authors: Meneses Marilyse de Oliveira , Andrade Elaine Maria Leite Rangel
Published: January 2024

Objetivo: verificar a relação entre sintomas de depressão, ansiedade, estresse e dependência de smartphone em estudantes de enfermagem na COVID-19. Método: estudo descritivo-analítico realizado com 206 estudantes de enfermagem. Para coleta de dados foram utilizados um instrumento de caracterização sociodemográfica e uso do smartphone adaptado da literatura e as seguintes escalas: Depression, Anxiety and Stress Scale e Smartphone Addiction Inventory. Os dados sociodemográficos e o uso do smartphone foram analisados por meio de estatísticas descritivas e a relação entre sintomas de depressão, ansiedade, estresse e dependência de smartphone foi analisada a partir de regressão logística múltipla. Resultados: a prevalência de dependência de smartphone em estudantes de enfermagem foi de 129 (62,6%) e houve relação entre sintomas de depressão moderada (p=0,049), grave/muito grave (p=0,005) e ansiedade leve (p=0,028) e grave/muito grave (p=0,019) e dependência de smartphone. Conclusão: os dados revelam que a construção e a implementação de políticas de uso do smartphone no contexto acadêmico e hospitalar para prevenção da dependência de smartphone e controle dos fatores de risco associados são necessárias.
Temperature curve of raw human milk heated by different methods: experimental study
Authors: Abrão Ana Cristina Freitas de Vilhena , Schmidt Gisele de Jesus , Mattar Maria José Guardia , Cruz Carla Santos , Barbosa Juliana de Barros , Daré Dariza Zimiani , Coca Kelly Pereira
Published: January 2024

ABSTRACT Objective: To analyze the temperature curve of raw or pasteurized human milk exposed to different heating methods. Method: Experiments with volumes of 5 ml to 100 ml of human milk were carried out between 2016 and 2021 and analyzed according to the exposure time by different heating methods. Descriptive statistics included the calculation of means, medians, minimum and maximum values, measures of dispersion and standard deviation. Results: The thermal curve made it possible to identify the heating of human milk close to body temperature when subjected to a water bath and microwaves. Milk exposed to room temperature (21°C) was unable to reach this temperature. When heated in a water bath at 40°C, smaller volumes reached body temperature between 3 and 5 minutes, while in a microwave at 50% power, practically all volumes reached temperature. Conclusion: The temperature curves of raw or pasteurized human milk were constructed, and it was possible to verify its behavior using different heating methods for administering the food in a neonatal intensive care unit, considering the volume, type and time of heating and temperature.
Update on Hemodialysis-Induced Multiorgan Ischemia
Authors: McIntyre Christopher W.
Published: January 2024

Hemodialysis is a life-saving treatment for patients with kidney failure. However, patients requiring hemodialysis have a 10–20 times higher risk of cardiovascular morbidity and mortality than that of the general population. Patients encounter complications such as episodic intradialytic hypotension, abnormal perfusion to critical organs (heart, brain, liver, and kidney), and damage to vulnerable vascular beds. Recurrent conventional hemodialysis exposes patients to multiple episodes of circulatory stress, exacerbating and being aggravated by microvascular endothelial dysfunction. This promulgates progressive injury that leads to irreversible multiorgan injury and the well-documented higher incidence of cardiovascular disease and premature death. This review aims to examine the underlying pathophysiology of hemodialysis-related vascular injury and consider a range of therapeutic approaches to improving outcomes set within this evolved rubric.‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬
An Undetected Echo of Tennyson's "Ulysses" in Walt Whitman's "Leaves of Grass"
Authors: Bertman Stephen Samuel
Published: January 2024

This discovery article explores the previously unrecognized semantic resonance between the concluding verses of Alfred Lord Tennyson's poem "Ulysses" and Walt Whitman's poem "The Untold Want." The English and American poets were not only contemporaries but also friends who admired each other's work and corresponded over the course of two decades. In pursuing a daring Ulysses-like voyage "to seek and find," Whitman was paying tribute to his fellow poet's questing spirit. 
Análisis ecológico de comunidades en la vegetación arbórea del parque Chicaque, Cundinamarca
Authors: Emilio Díaz-C Sebastián , Londoño-Hernández Derly Johana , Ariza-Corté William
Published: January 2024

Los bosques andinos son áreas fundamentales para la provision de servicios ecosistémicos –SE– de regulación hídrica y climática, por medio del secuestro de carbono; sin embargo, la dinámica antrópica ha llevado sus coberturas a un estado de transformación superior al 70%. En este contexto, es pertinente caracterizar, en un nivel multidimensional de la diversidad forestal, los relictos remanentes; por tanto, se realizó un análisis ecológico de la vegetación arbórea del parque natural Chicaque. Para tal fin, se hizó un muestreo simple al azar de 11 parcelas de 0,1 hectárea –ha– (10 x 100 m), recopilando la información de individuos con DAP ≥ 10 cm. Se encontró un valor medio de 17 especies y 58 individuos en 0,1 ha, a un coeficiente de variación de 36%; se estima un acumulado de 72 especies por hectárea. Las familias con mayor riqueza son Rubiaceae, Euphorbiaceae y Lauraceae. El dosel medio se encuentra entre los 12 y 15 m. La importancia y dominancia se concentra principalmente en C. angustifolia, P. excelsa y M. symplocoidea. Se estimó una cantidad de 20,62 ± 4,94 Mg 0,1ha-1 de biomasa aérea, 10,31 ± 2,47 Mg 0,1 ha-1 de carbono y 37,84 ± 9,06 Mg 0,1 ha-1 de CO2e; a un error de muestreo de 23,94%. Las especies que secuestran la mayor cantidad de carbono en su biomasa aérea son C. angustifolia, Q. humboldtii y M. symplocoidea. Las cantidades estimadas (206,22 ± 49,37 Mg ha-1) coinciden con los niveles medios de los bosques andinos del norte de Sudamérica. Se reconoce el aporte al SE de habitat, al conservar el pool genético de dos especies en categoría de amenaza (Q. humboldtii, C. montana). La vegetación arbórea presenta diversidad alfa media y condiciones ecológicas de bosque secundario de desarrollo tardío.
Evaluación de la inclusión de la larva de mosca doméstica (Musca domestica L.) como alternativa en la alimentación de Gallus domesticus en el municipio de Soracá, Boyacá
Authors: Castillo-Medina Evelin Danna Marcela , Torres-Neira Olga Lucía , González-Torre Yesid Orlando , Montaño-Campaz Milton Leoponcio
Published: January 2024

El objetivo de este trabajo fue evaluar la inclusión de harina de larva de mosca común (Musca domestica L.) en la alimentación de pollos de engorde de la línea Cobb, sobre los parámetros productivos, la calidad de la canal y la viabilidad económica. Se utilizaron 100 pollos broiler de la línea Cobb de un día de edad, distribuidos en un diseño completamente al azar con 4 tratamientos y 5 repeticiones de 5 aves en cada unidad experimental, por un periodo de 42 días. Los tratamientos consistieron en la sustitución del concentrado comercial por diferentes niveles de harina de larva (HDL), de la siguiente manera: T1: 100% concentrado; T2: 88% concentrado y 12% HDL; T3: 83% concentrado y 17% HDL y T4: 78% concentrado y 22% HDL. Las variables productivas evaluadas fueron: peso final, ganancia de peso y conversión alimenticia y las variables de calidad fueron: peso de canal, rendimiento en canal, rendimiento de pechuga y pierna pernil. Los resultados obtenidos para parámetros productivos en las aves no mostraron diferencias (P>0,05), los indicadores de calidad de la canal mostraron diferencias en el rendimiento de pierna pernil, siendo el tratamiento 1 el que obtuvo los mejores resultados (P<0,05). El mejor desarrollo de pechuga se obtuvo en el T4 (34,21% del peso de la canal). Se concluyó que la inclusión de harina de larvas de mosca doméstica genera un desarrollo similar a los pollos alimentados con piensos convencionales. Por otro lado, la utilización de esta harina en dietas para pollos de engorde disminuye los costos de producción en un 40%, siendo una buena estrategia de alimentación en las granjas avícolas.
Understanding the Psychological and Financial Correlates for Consumer Credit Use
Authors: CAKAR Tuna , ŞAHİN Türkay , ERTUĞRUL Seyit , SAYAR Alperen
Published: January 2024

This study investigated the behavioural and cognitive predictors of consumer credit usage to develop a behavioural credit risk assessment procedure for a factoring company. Participants completed surveys measuring personality traits, self-esteem, material and monetary values, compulsive and impulsive buying tendencies, self-control, and impulsiveness. Financial surveys also assessed financial literacy and knowledge of financial concepts. The results indicated that extraversion, conscientiousness, emotional stability, and experiential self-control were significant predictors of consumer credit usage. These findings suggest that a finance company can use these personality traits and financial characteristics to develop a more accurate and effective credit risk assessment procedure, such as psychometric tests.
Orta Gelir Tuzağı ve Vergi Gelirlerinin Kompozisyonu Arasındaki İlişki: Yükselen G20 Ülkeleri Örneği
Authors: MOĞOL Tayfun , PİRDAL Burak
Published: January 2024

Uzunca bir süre orta gelir düzeyinde takılıp kalarak yüksek gelir düzeyine ulaşamayan ülkelerin orta gelir tuzağına yakalanmış olabileceği yaygın olarak ifade edilir. Bu çalışmada, öncelikle, incelenen ülkelerin (Yükselen G20) orta gelir tuzağında olup olmadıkları ikinci nesil yapısal kırılmalı birim kök testlerinden olan düzeyde iki kırılmaya izin veren Narayan & Popp (ADF Testi) (Model A) yapısal kırılmalı birim kök testi ile araştırılmıştır. İkinci aşamada ise incelenen ülkelerde vergi gelirlerinin kompozisyonu ile gelir düzeyleri arasındaki muhtemel nedensellik ilişkisinin sınanması amacıyla Dumitrescu & Hurlin Panel Nedensellik Testi uygulanmıştır. Son aşamada ise analize konu ülkelerde gelirdeki artışın ve orta gelir tuzağından kurtulma durumunun vergi gelirlerinin kompozisyonu üzerindeki olası etkileri statik panel veri analizi yöntemiyle araştırılmıştır. Çalışmada, vergi gelirlerinin kompozisyonu ile ülkelerin gelir düzeyi arasında karşılıklı nedensellik ilişkisi tespit edilmiş olup aynı zamanda, gelirdeki artışın orta gelir tuzağında bulunan ülkelerde dolaylı vergilerin toplam vergi gelirleri içindeki payını artırmasına karşın, gelirdeki artış ile birlikte orta gelir tuzağından çıkışın sağlanması durumunda ise bu payın azalış sergilediği bulgulanmıştır.
D-8 Ülkeleri İçin Karbondioksit Emisyonun Yapay Sinir Ağları ile Tahmin Edilmesi: Levenberg-Marquardt Algoritması
Authors: ÇAY ATALAY Ayşe
Published: January 2024

Son yıllarda büyüme, kalkınma ve sürdürülebilirlik odaklı yaşam tarzı özellikle gelişmekte olan ülkeler için ayrı bir sorunsalı oluşturmaktadır. Bu çalışmada 1990-2020 yılları arasında tamamı gelişmekte olan ülkelerden oluşan D8 ülkeleri (Endonezya, Bangladeş, İran, Mısır, Malezya, Pakistan, Nijerya ve Türkiye) için kişi başı GSYH, kişi başı enerji tüketimi (yenilenebilir, fosil, toplam), kentsel nüfus artışı ve karbondioksit emisyonu, verileri kullanılarak yapay sinir ağları (YSA) yöntemi ile ülkelere ait karbondioksit emisyonu oranları tahmin edilmiştir. Çalışmada kurulan YSA modelinde veri tabanı verilerinin rastgele olarak %70’i eğitim, %15’i doğrulama ve %15’i test verilerine ayrılmıştır. Oluşturulan bu yapay sinir ağı, Levenberg-Marquardt algoritması ile eğitilmiştir. Modelin performans göstergelerinden Regresyon R değerleri eğitim verileri için 0,99, doğrulama verileri için 0,97 ve test verileri için 0,99 olarak belirlenmiştir. Modelde kullanılan tüm veriler için regresyon R değeri 0,99 olarak belirlenmiştir.
Türkiye İçin Ekonomik Yapısal Reform Ölçüm Yöntemlerinin Geliştirilmesi ve Büyüme Üzerindeki Etkilerinin İncelenmesi
Authors: YALÇINKAYA Ömer , KAYA Vedat , ERKAL Gökhan
Published: January 2024

Bu çalışmada, IMF-MONA (Monitoring of Fund Arrangements) programı sınıflandırmaları eşliğinde ekonomik yapısal reformların Türkiye için tanımlanması, 1990-2021 döneminde Türkiye Cumhuriyeti Cumhurbaşkanlığı Resmî Gazete arşivinden ölçümlenmesi ve ekonomik büyüme üzerindeki etkilerinin BF-ARDL modeliyle incelenmesi amaçlanmıştır. Çalışmada Cobb-Douglas üretim fonksiyonunun genişletilmesine dayanan ekonometrik modellerin çözümlenmesi sonucunda, gerçekleştirilen reformların Türkiye’nin büyümesi üzerinde finansal, mali ve reel sektörlerde pozitif/anlamlı ve ticari sektörde ise pozitif/anlamsız etkilere sahip olduğu belirlenmiştir. Bu sonuçlar, inceleme döneminde Türkiye’de gerçekleştirilen reformların büyümeyi desteklediğini göstermekte ve güçlendirilerek sürdürülebilmesinde önemli bir potansiyele sahip olduğuna işaret etmektedir.