bluuebunny/crossref_metadata_2025 huggingface dataset:
Application and Progress of Machine Learning in Pesticide Hazard and Risk Assessment
Authors: Yang Yunfeng , Zhong Junjie , Shen Songyu , Huang Jiajun , Hong Yihan , Qu Xiaosheng , Chen Qin , Niu Bing
Published: April 2023

Long-term exposure to pesticides is associated with the incidence of cancer. With the exponential
increase in the number of new pesticides being synthesized, it becomes more and more
important to evaluate the toxicity of pesticides by means of simulated calculations. Based on existing
data, machine learning methods can train and model the predictions of the effects of novel pesticides,
which have limited available data. Combined with other technologies, this can aid the synthesis of
new pesticides with specific active structures, detect pesticide residues, and identify their tolerable
exposure levels. This article mainly discusses support vector machines, linear discriminant analysis,
decision trees, partial least squares, and algorithms based on feedforward neural networks in machine
learning. It is envisaged that this article will provide scientists and users with a better understanding
of machine learning and its application prospects in pesticide toxicity assessment.

Long-term exposure to pesticides is associated with the incidence of cancer. With the exponential
increase in the number of new pesticides being synthesized, it becomes more and more
important to evaluate the toxicity of pesticides by means of simulated calculations. Based on existing
data, machine learning methods can train and model the predictions of the effects of novel pesticides,
which have limited available data. Combined with other technologies, this can aid the synthesis of
new pesticides with specific active structures, detect pesticide residues, and identify their tolerable
exposure levels. This article mainly discusses support vector machines, linear discriminant analysis,
decision trees, partial least squares, and algorithms based on feedforward neural networks in machine
learning. It is envisaged that this article will provide scientists and users with a better understanding
of machine learning and its application prospects in pesticide toxicity assessment.
Machine Learning Applications in the Study of Parkinson’s Disease: A
Systematic Review
Authors: Martorell-Marugán Jordi , Chierici Marco , Bandres-Ciga Sara , Jurman Giuseppe , Carmona-Sáez Pedro
Published: April 2023

Background:

Parkinson’s disease is a common neurodegenerative disorder that has been
studied from multiple perspectives using several data modalities. Given the size and complexity of these
data, machine learning emerged as a useful approach to analyze them for different purposes. These
methods have been successfully applied in a broad range of applications, including the diagnosis of Parkinson’s
disease or the assessment of its severity. In recent years, the number of published articles that
used machine learning methodologies to analyze data derived from Parkinson’s disease patients have
grown substantially.

Objective:

Our goal was to perform a comprehensive systematic review of the studies that applied machine
learning to Parkinson’s disease data

Methods:

We extracted published articles in PubMed, SCOPUS and Web of Science until March 15,
2022. After selection, we included 255 articles in this review.

Results:

We classified the articles by data type and we summarized their characteristics, such as outcomes
of interest, main algorithms, sample size, sources of data and model performance.

Conclusion:

This review summarizes the main advances in the use of Machine Learning methodologies
for the study of Parkinson’s disease, as well as the increasing interest of the research community in this
area.
Immunotherapy for Pediatric Gliomas: CAR-T Cells Against B7H3: A
Review of the Literature
Authors: Santiago-Vicente Yolanda , de Jesús Castillejos-López Manuel , Carmona-Aparicio Liliana , Coballase-Urrutia Elvia , Velasco-Hidalgo Liliana , Niembro-Zúñiga Ana María , Zapata-Tarrés Marta , Torres-Espíndola Luz María
Published: April 2023

Background:

B7H3 is a co-stimulatory molecule for immune reactions found on the surface
of tumor cells in a wide variety of tumors. Preclinical and clinical studies have reported it as a tumor target
towards which various immunotherapy modalities could be directed. So far, good results have been
obtained in hematological neoplasms; however, a contrasting situation is evident in solid tumors, including
those of the CNS, which show high refractoriness to current treatments. The appearance of cellular
immunotherapies has transformed oncology due to the reinforcement of the immune response that is
compromised in people with cancer.

Objective:

This article aims to review the literature to describe the advancement in knowledge on
B7H3 as a target of CAR-T cells in pediatric gliomas to consider them as an alternative in the treatment
of these patients.

Results:

Although B7H3 is considered a suitable candidate as a target agent for various immunotherapy
techniques, there are still limitations in using CAR-T cells to achieve the desired success.

Conclusion:

Results obtained with CAR-T cells can be further improved by the suggested proposals;
therefore, more clinical trials are needed to study this new therapy in children with gliomas.
WITHDRAWN: COVID-19: Mortality Rate (In Time) An Analysis of Publicly Available Data from 11 Countries to Calculate the Mortality Rate of COVID-19
Authors: Bosma Rien
Published: April 2023

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has
been withdrawn from the website of the journal Coronaviruses.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham editorial policy on article withdrawl can be found at https://benthamscience.com/editorialpolicies-main.php.

BENTHAM SCIENCE DISCLAIMER:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously
submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published
elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden,
and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate
action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors
agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.
The Excavation and Narrative Characteristics of Jeonghyobujeon
Authors:   Korean Language & Literature, Cho Jae-hyun
Published: April 2023

Jeonghyobujeon was recorded in Hangeul in 1914 and distributed mainly in Jeonju, Jeolla-do, and is a classic novel first introduced to academia. Jeonghyobujeon has the character of an ethical novel in the theme aspect and a novel with a trial in the composition aspect. The most influential thing in forming the narrative of Jeonghyobujeon is the story of “Ukong(于公)and DonghaeHyobu(東海孝婦)” contained in 󰡔HanSeo(漢書)󰡕71, ｢WuCengkwook(于定國)｣. Comparing the spatio-temporal backgrounds, characters, and major narratives of the two works, Jeonghyobujeon was created under the influence of ｢WuCengkwook(于定國)｣. Jeonghyobujeon composed a novel by featuring Kim Cheol-soo as a villain and inserting a story of suffering in hell under God's punishment. In addition, Wukong of Jeonghyobujeon is embodied in the form of a much more insightful official than Wukong recorded in ｢WuCengkwook(于定國)｣. Woo Gong of ｢WuCengkwook(于定國)｣ is only in a position to persuade the fact that DonghaeHyobu(東海孝婦) is innocent. However, WuGong in Jeonghyobujeon, made a dramatic character by consoling Mrs. Jeong's ghost by making a direct ruling and later bringing her back to the real world. Jeonghyobujeon was novelized based on Chinese records, but in the process, it was meaningful in that it was newly created and novelized by actively expanding the role of characters and inserting the heroine's fantasy experience. I think it will be a major work that can examine the relationship between acceptance and influence of Chinese literature in the study of novels in the late Joseon Dynasty.
The narrative of love and symptomatic reading: focused on Park Young-joon's novels in liberation period
Authors:   Korean Language & Literature, Kim Young-kyung
Published: April 2023

This paper aims to examine the psychological conflicts and problems of self-identification that occurred when writers outside the community attributed to the community, focusing on Park Young-joon's novels in liberation period, from the perspective of the narrative of love. In the literature of Park Young-joon, the issue of his track record in Manchuria and his transfer is important. This has been mainly discussed from the perspective of the author's 'self-identification'. However, compared to other writers at the same time, Park did not reveal his past actively or express his beliefs persuasively. Rather, it can be seen that he expressed his longing for recognition through the the narrative of love by passive characters. Park Young-joon's works during the liberation period show a significant change in trend from the establishment of the separate government. Prior to the establishment, many works deal with the question of how to liquidate the past and live a new life. In addition, the characters attempted to seek a positive outlook by dealing with the subject of recognition, development, and inclusion through love. In addition, many works have narrated their experiences in Manchuria. In the world of his works, if colonial works are centered on the story of breaking wishes and fantasies in Manchuria, post-liberation works tend to cover up the past and protect himself. However, after the establishment of the separate government, in the world of Park Young-jun's works, “love” is reserved, and there is a characteristic that no positive future is sought or progress is made. Rather, it is depicted as the main theme of the separation and disconnection of characters who want to love. Park Young-jun's works in liberation period have something in common that most of them are based on a longing for recognition. While the narrative of Manchuria are works that seek to strengthen the rights and solidarity among members of the community by differentiating the world outside the Korea, love narratives have something in common that all the characters surrounding love are based on a longing for recognition. These characteristics appear in his works as detailed changes in political and historical reality after liberation.
Prevalence of smoking and its associated health effect among Saudis: A Nationwide study (Preprint)
Authors: AlNujaidi Heba , ALAnsary Naof , AlShawan Deema , AlSaif Atheer , Ali Uzma , Muhammad Mehwish Hussain , Albagmi Faisal , Bah Sulaiman , Althumiri Nora A. , BinDhim Nasser
Published: April 2023

BACKGROUND

Tobacco smoking remains one of the leading causes of preventable deaths globally. There is a lack of up-to-date reports on the prevalence of smoking and its associated risk factors among the Saudi population.

OBJECTIVE

This study aims to provide a recent smoking prevalence and compare smokers vs. non-smokers and their effect on different chronic diseases.

METHODS

Nationwide population-based study.,secondary analysis of data from the Sharik Health Indicators Surveillance System (SHISS). The SHISS proportionate quota sampling method was employed to obtain an equitable distribution of adult participants, stratified by age and gender. A total of 23098 participants' records who were enrolled in the SHISS in 2020 were analyzed in this study.

RESULTS

Overall, 28.05 % of Saudis reported that they currently smoke. This prevalence was 45.3 % among males and 11.11% among females. The prevalence of smoking varied by age; those aged 30-39 were the highest (34%) and lower among 18-19 years old (18.4%), with the Western region having the highest number of smokers in the Kingdom. Smokers had a higher chance of suffering from diabetes (18.2%), high cholesterol (27.2%), high blood pressure (35%), and two times higher chances of having a stroke and cancer than their non-smokers counterparts.

CONCLUSIONS

The study findings suggest that implementing tobacco control policies in Saudi Arabia has not effectively reduced smoking prevalence. Action is needed to prevent the significant and growing smoking-related chronic disease burden from further increasing as the Saudi population ages.

CLINICALTRIAL

NA
Leveraging Electronic Health Record Technology and Team Care to Address Medication Adherence: Protocol for a Cluster Randomized Controlled Trial (Preprint)
Authors: Blecker Saul , Schoenthaler Antoinette , Martinez Tiffany Rose , Belli Hayley M , Zhao Yunan , Wong Christina , Fitchett Cassidy , Bearnot Harris R , Mann Devin
Published: April 2023

BACKGROUND

Low medication adherence is a common cause of high blood pressure but is often unrecognized in clinical practice. Electronic data linkages between electronic health records (EHRs) and pharmacies offer the opportunity to identify low medication adherence, which can be used for interventions at the point of care. We developed a multicomponent intervention that uses linked EHR and pharmacy data to automatically identify patients with elevated blood pressure and low medication adherence. The intervention then combines team-based care with EHR-based workflows to address medication nonadherence.

OBJECTIVE

This study aims to describe the design of the Leveraging EHR Technology and Team Care to Address Medication Adherence (TEAMLET) trial, which tests the effectiveness of a multicomponent intervention that leverages EHR-based data and team-based care on medication adherence among patients with hypertension.

METHODS

TEAMLET is a pragmatic, cluster randomized controlled trial in which 10 primary care practices will be randomized 1:1 to the multicomponent intervention or usual care. We will include all patients with hypertension and low medication adherence who are seen at enrolled practices. The primary outcome is medication adherence, as measured by the proportion of days covered, and the secondary outcome is clinic systolic blood pressure. We will also assess intervention implementation, including adoption, acceptability, fidelity, cost, and sustainability.

RESULTS

As of May 2023, we have randomized 10 primary care practices into the study, with 5 practices assigned to each arm of the trial. The enrollment for the study commenced on October 5, 2022, and the trial is currently ongoing. We anticipate patient recruitment to go through the fall of 2023 and the primary outcomes to be assessed in the fall of 2024.

CONCLUSIONS

The TEAMLET trial will evaluate the effectiveness of a multicomponent intervention that leverages EHR-based data and team-based care on medication adherence. If successful, the intervention could offer a scalable approach to address inadequate blood pressure control among millions of patients with hypertension.

CLINICALTRIAL

ClinicalTrials.gov NCT05349422; https://clinicaltrials.gov/ct2/show/NCT05349422

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/47930
NANOSPONGES - A REVOLUTIONARY TARGETED DRUG DELIVERY NANOCARRIER: A REVIEW
Authors: ANKEM BHAGYAVATHI , KUCHARLAPATI SAI LAKSHMI TEJASWI , MAGAPU SAHITYA DEEPTHI , B BHAVANI
Published: April 2023

Effective targeted drug delivery systems have long been a dream, but have been largely hampered by the complex chemistries involved in developing new systems. The creation of novel colloidal carriers known as nanosponges has the potential to resolve these issues. An innovative and developing technology called nanosponge provides regulated medication delivery for topical application. Highly porous nanosponges have a unique capacity to entrap active molecules and have the advantage of programmable release. Nanosponges are small three-dimensional porous structures about the size of nanometer that can contain many different drugs. These tiny sponges can move throughout the body until they meet a specific target site and attach to surfaces and begin to release the drug in a controlled and predictable manner. Because the drug can be delivered to a specific target site instead of circulating throughout the body, it is more effective for a given specific dose. They are easy to make and safe for biological use. Different types of cyclodextrins can be cross-linked using a carbonyl or a dicarboxylate chemical as a cross-linker to create nanosponges. This groundbreaking technology has been extensively investigated for the delivery of medications for oral, topical, and parental administrations. Vaccines, antibodies, proteins, and enzymes can all be effectively transported via Nanosponges. The current review emphasizes the methods, advantages, disadvantages, characterization, and applications of nanosponges.
COMPLICATED INGUINAL HERNIA OR INGUINAL DERMOID: A DIAGNOSTIC DILEMMA
Authors: BASRA SHARANJIT SINGH , VERMA VISHAL , HIREMATH RAVISHEKAR N , MITTAL MOHIT
Published: April 2023

Simple or complicated inguinal hernias are the common inguinal lumps of any surgical emergency or outpatient settings. However, inguinal hematoma, abscess, enlarged inguinal lymph node, undescended testis, lipoma, or encysted hydrocele of the spermatic cord are few relatively less common entities seen in inguinal region whereas inguinal supernumerary pectineus bursa, preperitoneal lipoma, pedunculated uterine fibromyoma, angioma of uterine ligament, inguinal endometriosis, aneurysm of femoral artery, saphena varix, and thrombophlebitis are extremely uncommon entities of the groin region. We present an interesting case in which patient presented with painful firm lump in inguinal region and the history and clinical examination was consistent with the diagnosis of an incarcerated inguinal hernia but intraoperative findings amazed us and subsequently histopathological analysis labeled it a dermoid cyst.
STUDY ON CLINICAL PROFILE OF ACUTE PANCREATITIS FROM A TERTIARY CARE TEACHING INSTITUTE OF WESTERN UTTAR PRADESH
Authors: Singh Jaipal , Mawar Alok , Patel Jaya , Manyal Rohit , Lohokare Rajeev
Published: April 2023

Objective: The objective of this study was to study the clinical profile of subjects diagnosed and managed for acute pancreatitis at a tertiary care teaching institute of western Uttar Pradesh. Methods: All the cases diagnosed and managed for acute pancreatitis at the study place and during the study time formed the study population. All the cases were followed up till the outcome of the case. A detailed pro forma was designed to capture relevant details of study subjects. Results: Underlying cause of the clinical condition was noted as alcoholic in nature by majority (80%) of the study subjects. In ten patients (16.7%) reason for the pancreatitis could not be ascertained despite extensive evaluation. Common complications of the clinical condition were noted as pleural effusion (n=12, 20%), followed by ascites (n=9, 15%) and acute fluid collection (n=5, 8.3%). Morality was seen among two patients (3.3%). Conclusion: In this region of the western Uttar Pradesh, alcohol is the most frequent cause of acute pancreatitis. Males are more likely to get the condition, and it typically manifests in the fourth decade of life. Biochemical and radiological results supplement the primary clinical diagnosis.
PARADIGMATIC AGE SHIFT OF HYPERTENSION DISEASE: A STUDY AMONG YOUNG ADULTS
Authors: Pandey Dhurvendra , Guleri Sunil kant , Sinha Umesh , Pandey Smriti , Tiwari Shivam
Published: April 2023

Objectives: The objectives of study are to assess the magnitude of hypertension and identify various factors associated with hypertension among participants.
Methods: A cross-sectional study done on attendees and patients coming to medicine OPD in a tertiary care hospital in Madhya Pradesh. The earlier diagnosed hypertensive cases were excluded from the study and 500 participants were studied. Clinical measurements and predesigned semi-structured questionnaire were used for data collection. Chi-square test was applied to find association of risk factors with hypertension.
Results: About 21.6% of the participants were diagnosed for hypertension. The increasing age, obesity, smoking, alcoholism, and daily salt intake above two teaspoonfuls had significant association with occurrence of hypertension (p≤0.05).
Conclusion: The magnitude of hypertension is increasing among adult population and has strong association with increasing age and other risk factors. Hence, the early diagnosis with the help of screening tools is needed. Opportunistic screening of all adults coming in contact of health system will help the pool of diagnosed cases of hypertension and help to reduce burden of complications caused by hypertension.
LOW TRIIODOTHYRONINE (T3) SYNDROME IN ACUTE HEART FAILURE AND ASSOCIATION WITH SHORT-TERM OUTCOME
Authors: G ASWIN KUMAR , ZACHARIAH SUE ANN
Published: April 2023

Introduction: Heart failure (HF) is a clinical syndrome caused by structural and/or functional cardiac abnormality that causes decreased cardiac output and/or elevated intracardiac pressures. The prognosis of cardiac diseases may be negatively impacted by low-T3 states and was independently linked to higher all-cause mortality in hospitalized HF patients.
Objectives: The objectives of the study were to find an association between low T3 syndrome and short-term outcome in patients admitted with acute HF.
Methods: 176 patients diagnosed as acute HF fulfilling inclusion criteria were enrolled. Serum fT3, fT4, and thyroid-stimulating hormone were measured. Patients were followed up and length of hospital stay, need for inotropes, mechanical ventilation, and intensive care unit (ICU) facility were compared with thyroid function tests. End points were discharge or death. Data were entered into structured pro forma and analyzed.
Results: There was a statistically significant association between need for ICU/high dependency unit (HDU) facility care and T3 status (χ2=27.82; p<0.001). There was a statistically significant association between the need for mechanical ventilation with the levels of T3 (χ2=16.14; p<0.001). There is a statistically significant difference in mean T3 among the patients who expired and patients who were discharged (2.31±0.74 vs. 1.71±0.66; p=0.019).
Conclusion: Low T3 correlated with a higher rate of ICU/HDU admissions (53.5% vs. 14.7%, p<0.001) and an increased need for invasive mechanical ventilation (35.6% vs. 9.3%, p<0.001). Low T3 syndrome is frequently found in patients with acute HF and is associated with a poor short-term outcome in terms of need for intensive care and mechanical ventilation.
PSYCHOMOTOR RECOVERY AFTER INTRAVENOUS DEXMEDETOMIDINE INFUSION AS A PART OF BALANCED ANAESTHESIA – AN OBSERVATIONAL STUDY
Authors: KHALAM ANZALNA A , VARGHESE REGIMOL V , R RATHEESHKUMAR
Published: April 2023

Objective: The aim of the study was to determine the recovery of psychomotor function from balanced anesthesia with and without intravenous (IV) dexmedetomidine infusion as an adjunct.
Methods: A prospective and observational study was conducted in a tertiary care teaching hospital for 12 months. A total of 170 patients (American Society of Anaesthesiologists 1 and 2) in the age group of 18–50 years scheduled for elective surgery under general anesthesia with an anticipated duration of <3 h received either dexmedetomidine infusion (Group D) or not (Group S). Recovery of psychomotor function postoperatively was assessed with trieger dot test (TDT), digit symbol substitution test (DSST), and intraoperative fentanyl requirement in both groups. Data collected were analyzed using SPSS version 16.
Results: Both groups were comparable with respect to demographic variables. Psychomotor recovery assessed by TDT showed statistically significant early recovery in Group D compared with Group S. This was seen in the number of dots missed, maximum distance of dots missed as well as in the average distance of dots missed at post-operative time intervals of 30 min, 60 min, 90 min, and 120 min. Similarly, DSST revealed early recovery at these time points. There was a significant decrease in the intraoperative fentanyl requirement in Group D compared with Group S.
Conclusion: The addition of dexmedetomidine to the balanced anesthetic technique significantly hastened the psychomotor recovery.
Sustainable and No Contact Attendance System
Authors: Koushik Margam , Shiva Ananthula , Reddy Sheelam Vikas , Chowbey Dr. Abhishek
Published: April 2023

Abstract: This initiative makes use of RFID technology to keep track of every student who enters the classroomand to determine how long they will spend there. Every student is given an RFID tag under the suggested system. Taking attendance is a procedure. can be carried out by putting the card close to theRFID Reader, which will record all the necessary information about the pupil in the Excel Spreadsheet. A form of electronic device with a small antenna and a chip is known as an RFID (Radio Frequency Identification) device. Barcode scanners are no longer necessary thanks to RFID (Radio Frequency Identification). It generates a special identification number for that item, which must be scanned to obtain the information, just like a bar code or magnetic strip
The Impact of Microfinance on Economic Growth and Poverty Reduction in Malawi
Authors: Kamfose Elina Chamama , Agila Dr. G.
Published: April 2023

Abstract: Poverty reduction has been a major concern in Malawi for a long time. Today, Microfinance has become an important instrument for poverty alleviation in developing countries. This paper aims to assess the Impact of Micro finance activities on Malawi’s economic growth and poverty reduction. The study findings will be of special importance for policy makers and stakeholders who may benefit from these results in improving regulations and strategies to strengthen the microfinance sector as main player in the financial system in Malawi. For this study 70 respondents from microfinance institutions were considered and surveyed using a structured questionnaire and interviews. The data collected is analysed with tables, percentages and diagrams using Microsoft Excel.
Agro Analysis System for Precision Agriculture
Authors: Kotpalliwar Priyanka , Barmate Mayuri , Satpute Prachi , Manapure Damini , Hassan Mohammad
Published: April 2023

Abstract: Huge amount of data is collected by the sensors from the end. Subsequently, this considerably big amount of data must be processed, analyzed and stored in a cost effective way. In this manner, an enormous pool of computing resources and storage must be provided to compute this vast amount of data. We focused on introducing the latest technologies such as sensors, WSN to radically revise approaches to agriculture by collecting the data about the various parameters of soil, analyzing the data and performing the computations, giving the best optimal solutions for the farming. The application of computing in the agricultural economy will open up a vast range of prospects, such as the vast storage of agriculture information, the cloud management of agricultural production process, the storage of agricultural economy information, early-warning and policymaking based on the agricultural products market, the tracing management of agricultural products quality.
Modalities in Khofiah Indah Parawansa's Victory in the 2018 East Java Governor Election
Authors: Zahro Maharina Novia , Sujoko Anang
Published: April 2023

The dominance of the Muslim community in East Java and the existence of a patriarchal culture affect voter behavior, making it difficult for women to become governors. This study aims to reveal the success factors of women, namely Khofifah Indah Parawansa, to become Governor in East Java from the aspect of his modalities based on Piere Boerdiau's perspective. This research uses a type of qualitative research with narrative analysis. This research shows that Khofiah's victory is inseparable from the ability to maximize all types of modalities owned, namely social capital, cultural capital, and symbolic capital. All types of modalities were then packaged very well by the political public relations of Khofifah's winning team so as to win a lot of public sympathies and greatly contribute to Khofiah's victory.
Legal Protection for Women Victims of Psychological Domestic Violence Based on Enactment Number 23 of 2004
Authors: Muryatini Ni Nyoman
Published: April 2023

According to National Commission on Violence against Women’s annual record in 2020, within a period of 12 (twelve) years, violence against women increased by 792%. It means that violence against women in Indonesia for 12 (twelve) years increased almost 8 (eight) times. Psychological violence against women in the household is an act against the law, a violation of human rights, a crime against human dignity, and a form of discrimination that must be abolished. This study aims to examine the legal protection for women victims of psychological violence in the household based on the enactment of domestic violence elimination. The method used in this research is normative legal research which makes the norm system the centre of its study with the aim of providing legal arguments as a basis for determining whether an event is right or wrong and how the event should be according to law. The results showed that the government has made efforts to protect women victims of psychological violence in the household. Preventively bypassing the constitution of domestic violence elimination and repressively by providing protection and services needed by victims in the context of recovery. Domestic violence is included in the complaint offence; therefore, the victim must report to the investigator related to the violence experienced so that legal proceedings can be carried out immediately.
Customary Law during the Covid-19 Pandemic: Supporting Local Government's Policy
Authors: Oka Parwata Anak Agung Gede , Laksana I Gusti Ngurah Dharma , Harmini A. A. A. N. , Pranajaya Made Dandy
Published: April 2023

The covid-19 pandemic has become a national disaster, therefore the participation of all parties is needed in efforts to handle this disaster. Traditional villages with their customary law have a strategic role in handling Covid-19 starting from managing their territory to distributing social assistance. Through traditional village institutions, the Bali Provincial Government uses local wisdom in increasing community participation and institutions to be actively involved in handling activities and overcoming the impact of Covid-19. This study aims to determine the role of customary law to support government policies in handling Covid-19 in Bali. This study is a descriptive study in which the method used is a normative legal research method, using a statutory approach, a historical approach, a conceptual approach, a philosophical approach, and a case approach. The legal materials used are primary legal materials, secondary materials, and non-legal materials. Based on the research conducted, it was found that Balinese customary law plays a role in supporting government policies in handling Covid-19 in Bali because it is in accordance with the philosophy and principles of customary law adopted by the Balinese indigenous people.
REFLECTIONS ON THE FATE OF THE COURT OF CASSATION IN POST-REFORM RUSSIA, PROVOKED BY A. N. VERESHCHAGIN'S BOOK "The Senate of Cassation. (1866-1917). Essays on the structure and activities of the Supreme Court of the Russian Empire" (Moscow: Pravo Publishing Group, 2022. – 616 p.)
Authors:   Российская академия народного хозяйства и государственной службы при Президенте Российской Федерации, Москва, Россия, Константин Петрович Краковский
Published: April 2023

The presented material reviews the book by A.N. Vereshchagin "The Senate of Cassation. (1866-1917). Essays on the structure and activities of the Supreme Court of the Russian Empire" (Moscow: Publishing Group "Law", 2022. – 616 p.). The author of the review gives a critical analysis of the "scientific biography" of the «Supreme Court» of the Russian Empire considered in this study.
INSTITUTE OF AMANATISM IN THE POLITICAL CULTURE OF THE AMBASSADORIAL PERIOD
Authors:   Карачаево-Черкесский институт гуманитарных исследований, Черкесск, Россия, Фатима Анатольевна Озова
Published: April 2023

During the Caucasian War (1763–1864), a stereotype that still exists today was formed: amanat is a hostage. In fact, this historicism was polysemantic. The historical term "amanat" was borrowed into Russian at the beginning of the 17th century meaning "diplomatic hostage". This article provides an analysis that reveals its connection with customary law (the custom of amanatism) and with the political culture (the institution of diplomatic hostage-taking / amanatism) of many peoples of the world.
Evaluación del impacto psicosocial del COVID-19 estudio preliminar y orientaciones para una estrategia de atención psicosocial desde el CIAPSO
Authors: Rebolledo Cortés Henry Steven , Vargas Hurtado Gloria Isabel , Vargas Paredes Shyrley Rocío
Published: April 2023

Este documento se propone mostrar los resultados parciales de una investigación que mide el impacto impacto psicosocial y socioeconómico del COVID-19 en la población colombiana. Se presentan algunas consideraciones conceptuales, reflexiones investigativas y proyecciones. También se incluyen algunos datos de la investigación en el ámbito de impacto psicológico y social, una reflexión para pensar posibles abordajes e intervenciones para la atención psicosocial a familias, niños, niñas, jóvenes y adul-tos afectados por los efectos de la pandemia, que se está materializando desde una propuesta del grupo de investigación Pasos de Libertad desde el CIAPSC de la UNAD.
Resiliencia en mujeres víctimas del conflicto un factor de transición de la dificultad a la oportunidad
Authors: Alba Pinzón Zaida Ximena , Guzmán Díaz Sandra Milena , Solarte Artunduaga Liliana , Ariza Camacho Rubén Darío
Published: April 2023

Este texto pretende compartir algunos resultados previos y reflexiones producto del proceso de investigación que aborda el contexto de las mujeres víctimas del conflicto armado en el municipio de Pitalito, el cual se ha realizado por medio de narrativas individuales y mediante la investigación acción participativa con la finalidad de recolectar información valiosa en torno a la problemática, que es traducida por un sinnúmero de hechos victimizantes que acarrean afectaciones psicológicas e impactan los estilos de afrontamiento y los mecanismos de defensa de esta población. Por medio del trabajo articulado entre las mujeres participantes y el grupo de estudiantes y tutores del semillero de investigación Contacto se construyen nuevamente conceptos y conocimientos, a partir de esas historias en momentos de adversidad, que llevan a la comprensión de los factores resilientes presentes como factores carenciales en este tipo de población vulnerable, que facilitarán la construcción de nuevo conocimiento para aportar en la construcción del tejido social de la región.
Targeting Cancer Cell Signaling Using Precision Oncology Towards a Holistic Approach to Cancer Therapeutics
Authors: Kumar Manish
Published: April 2023

The mutational changes occurring in the regulatory genes responsible for
the maintenance of optimal cell growth and proliferation gradually lead
to cancer progression and metastasis. Furthermore, patients with the
same cancer types often respond differently to different cancer
therapies, indicating the need for a patient-specific treatment regimen
for the disease. Precision 34 oncology is the new field of cancer
research that relies on genetic profiling of individual tumors  to
identify targetable alterations for custom-tailored personalized
treatment of the disease. It is to rely upon the genomic study of cancer
cells to get a clear picture of the prognosis and pathways involved in
disease progression and to look for the means to selectively target them
for a cure. This article intends to briefly explain the foundations and
frontiers of precision oncology in the context of technological advances
being made in this direction to assess its scope and importance in the
realization of a proper cure for cancer.
A conceptual framework linking pollen limitation and seed dispersal effectiveness
Authors: Leal Laura , Koski Matthew
Published: April 2023

Seed production and dispersal are crucial ecological processes impacting
plant demography, species distributions, and community assembly.
Plant-animal interactions commonly mediate both seed production and seed
dispersal, but current research often examines pollination and seed
dispersal separately, which hinders our understanding of how pollination
services affect downstream dispersal services. To fill this gap, we
propose a conceptual framework exploring how pollen limitation can
impact the effectiveness of seed dispersal for endozoochorous and
myrmecochorous plant species. We summarize the quantitative and
qualitative effects of pollen limitation on plant reproduction and use
Optimal Foraging Theory to predict its impact on the foraging behavior
of seed dispersers. In doing so, we offer a new framework that poses
numerous hypotheses and empirical tests to investigate downstream
effects of pollen limitation on seed dispersal effectiveness and,
consequently, post-dispersal ecological processes occurring at different
levels of biological organization. Finally, considering the importance
of pollination and seed dispersal outcomes to plant eco-evolutionary
dynamics, we discussed the implications of our framework for future
studies exploring the demographic and evolutionary impacts of pollen
limitation for animal-dispersed plants.
Adaptive Anti-disturbance Switching Control for Switched T-S Fuzzy Systems
Authors: Zhao Ying , Gao Yuxuan , Sang Hong , Niu Ben
Published: April 2023

In this paper, an adaptive anti-disturbance switching (AADS) control
strategy is proposed for switched Takagi-Sugeno fuzzy systems (ST-SFSs)
subject to multi-source disturbances. The disturbances consist of two
parts: the available unmodeled disturbance and the disturbance modeled
by dynamic neural network. Firstly, a novel adaptive disturbance
observer is designed to approximate the dynamic neural network modeled
disturbance. Secondly, the attenuation performance from the output to
the available disturbance is analyzed by the L 2 gain index. Thirdly, a
controller based on the adaptive disturbance observer is constructed for
the ST-SFS under the average dwell time switching signal limitation.
Further, under the designed adaptive disturbance observer, and the
controller, a sufficient condition is established for the ST-SFS to
realize multi-source disturbance suppression (DS). Finally, a
mass-spring-damping simulation example is given to verify the
rationality of the established AADS control scheme.
EFFECT OF RESPIRATORY TRAINING DIGITAL GAME ON RESPIRATORY FUNCTIONS, AND PSYCHOLOGICAL STATUS IN CHILDHOOD ASTHMA
Authors: Gokcek Ozden , Huzmeli Esra Dogru , Elibol Nuray , Tugral Yagmur , Lekesiz Eren , El Çiğdem , Kan Ahmet , Yılmaz Basak , Baser Miray
Published: April 2023

Objective: Asthma is a chronic obstructive disease that is
common in children worldwide. This study aims to examine the effects of
a digital game designed for respiratory training in childhood asthma.
Methods: Fifteen children aged 8-14 years with asthma were
included in the study. There were two groups a digital game group (n=9)
and a control group (n=6). Demographic information of the children was
recorded. Pulmonary function test (PFT) was evaluated with a portable
spirometer (Spirobank MIR), the quality of life of the children was
evaluated with the Paediatric Asthma Quality of Life Questionnaire and
psychological status was evaluated with the child depression scale.
Respiratory training was given to the digital game group with a digital
game. The control group was followed with medication. Both groups were
evaluated at baseline and after 3 weeks. Results: In the
digital game group; It was observed that there was an increase in PFT,
sub-parameters of the PAQLQ questionnaire, and the total score after the
treatment (p<0.05). In addition, it was determined that there
was a significant decrease after the treatment according to the
questionnaire used for the change in the psychological status of the
children (p<0.05). Conclusion: It was determined that
respiratory training given with digital games had a positive effect on
children’s psychological state, pulmonary function test, and quality of
life.
Polysilicon-based tunnel junction Si solar cells with machine learning for tandem cell applications
Authors: Park HyunJung , Morisset Audrey , Kim Munho , Lee Hae-Seok , Hessler-Wyser Aïcha , Haug F-J , Ballif Christophe
Published: April 2023

Tandem solar cells are a key technology to exceed the theoretical
efficiency limit of single-junction cells. One of the most promising
combinations is the silicon-perovskite tandem cells, considering their
potential for high efficiency, large-area fabrication, and low cost.
Whereas most research focuses on improvements in each subcell, another
key challenge relies on the tunnel junction that connects subcells and
affects overall cell characteristics. Here, the first demonstration of
tunnel junctions using a stack of
p/n polysilicon deposited directly
on the passivating tunnel oxide are shown to overcome the drawbacks of
conventional metal oxide-based tunnel junctions including low tunneling
efficiency and sputter damage. Furthermore, using Random Forest
analysis, high implied open circuit voltages over 700 mV in the bottom
cell with the polysilicon tunnel junction are achieved. Their contact
resistivities are as low as 500 mΩ·cm, suggesting FF
losses of less than 1 %abs for the operating conditions of a tandem
cell.
SARS-CoV-2 infection in children with Cystic Fibrosis: A Cross-sectional Multicenter Study in Spain. New waves, new knowledge.
Authors: Mondejar-López Pedro , Moreno-Galarraga Laura , Manuel Cristina De , Castro Enrique Blitz , Bravo-Lopez Maynor , Gartner Silvia , Pérez-Ruiz Estela , Caro-Aguilera Pilar , Santiago Veronica Sanz , López-Neyra Alejandro , Luna-Paredes Maria , Gonzalez Miguel Garcia , Costa Jordi , Cols-Roig Maria , Delgado-Pecellín Isabel , Castillo-Corullón Silvia , Valbuena Marta Ruiz de , García-Marcos Patricia W. , Fernandez Antonio Aguilar , Martín Carlos , Sanchez Mª Verisima Barajas , Medina Orlando Mesa , Bover-Bauza Cati , Mulet Joan Figuerola , Avilés Belén García , Saez Mª Jesus Rodriguez , Garcia-Magan Carlos , Marruecos Patricia Juarez , Gutierrez-Martinez Jose Ramon , Cortell-Aznar Isidoro , Gomez-Pastrana David , Miguelez M. Valle Velasco , Barrio M. Isabel , Sanchez-Solis Manuel , Cruz Óscar Asensio de la , Pastor-Vivero Maria Dolores
Published: April 2023

Introduction Viral infections are associated with pulmonary
exacerbations in children with Cystic Fibrosis (cwCF), but after 3 years
of SARS-CoV-2 pandemic, whether cwCF are at higher risk of developing
COVID-19 or its adverse consequences remains controversial.
Methods We conducted an observational, multicenter,
cross-sectional study of cwCF infected by SARS-CoV-2 between March 2020
and June 2022, (1 to 6
COVID-19 pandemic waves) in Spain. The study aimed to describe patients’
basal characteristics, SARS-CoV-2 clinical manifestations and outcomes,
and whether there were differences across the pandemic waves.
Results During study time, 351 SARS-CoV2 infections were
reported among 341 cwCF. Median age was 8.5 years (range 0-17) and 51%
were female. Cases were unevenly distributed across the pandemic, with
most cases (82%) clustered between November 2021 and June 2022 (6
wave, also known as Omicron Wave due to the higher
prevalence of this strain in that period in Spain). Most cwCF were
asymptomatic (24.8%) or presented with mild Covid-19 symptoms (72.9%).
Among symptomatic, most prevalent symptoms were fever (62%) and
increased cough (53%). No multisystem inflammatory syndrome (MIS-C),
persisting symptoms, long-term sequelae or deaths were reported.
Conclusions Spanish current data indicate that cwCF do not
experience higher risks of SARS-CoV-2 infection nor worse health
outcomes or sequelae. Changes in patients’ basal characteristics,
clinical courses and outcomes were detected across waves. While the
pandemic continues, and new SARS-CoV-2 variants are being identified, a
worldwide monitoring of COVID-19 in pediatric CF patients is needed.
Micro-Scale Simulation of Adsorption-Diffusion Behaviors of Nanoparticles onto Oil/Water Interface
Authors: Ke Can , Yuan Bin , Li Yue , Liu Xvpeng , Han Mingliang , Hou Huilin
Published: April 2023

A novel, hybrid pore-scale simulation method using Lattice-Boltzmann
(LB) coupled with Langevin-Dynamics (LD) is proposed to investigate the
physics of nanoparticles onto oil/water interface. By the means of the
new LB-LD coupling model, the adsorption and diffusion characterization
of nanoparticles onto oil/water interface are investigated. Moreover, by
introducing interference coefficient and non-equilibrium time, a
modified Langmuir adsorption equation is first established by more
accurately quantifying the adsorption characterization of nanoparticles
and the consequent impacts onto oil/water interfacial tension, of which
the classical Langmuir adsorption equation cannot take account. For a
target representative example of SiO2 nanoparticles, it is observed that
small-size nanofluids with high concentration could accelerate the
adsorption of nanoparticles and therefore help decrease oil/water
interface tension. In addition, both the lateral and longitudinal
diffusion coefficients of nanoparticles into the water phase and onto
oil/water interface are obtained, and of which the underlying mechanisms
are explained in details.
Hyper-local temperature prediction using detailed urban climate informatics
Authors: Li Peiyuan , Sharma Ashish
Published: April 2023

Modeling urban microclimate accurately is challenging due to the high
surface heterogeneity of urban land cover and the vertical structure of
street morphology. Recent years have witnessed significant efforts in
numerical modeling and data collection of the urban environment.
Nonetheless, it is difficult for the physical-based models to fully
utilize the high-resolution data under the constraints of computing
resources. The advancement in machine learning techniques offers the
computational strength to handle the massive volume of data. In this
study, we proposed a machine learning approach to estimate point-scale
street-level air temperature from the urban-resolving mesoscale climate
model and a suite of hyper-resolution urban informatics, including
three-dimensional urban morphology, parcel-level land use inventory, and
a dense weather observation network. We implemented this approach in the
City of Chicago as a case study. The proposed approach vastly improves
the resolution of temperature predictions in cities, which will help the
city with walkability, drivability, and heat-related behavioral studies.
Moreover, we tested the model’s reliability on out-of-sample locations
to investigate the application potentials to the other areas. This study
also aims to gain insights into next-gen urban climate modeling and
guide city observation efforts to build the strength for the holistic
understanding of urban microclimate dynamics.
A convergence theorem for ap−Henstock-Kurzweil integral and its relation to topology
Authors: Kalita Hemanta , Hazarika Bipan
Published: April 2023

In this paper we discuss about the ap?Henstock-Kurzweil integrable functions on a topological vector spaces. Basic results of ap?Henstock-Kurzweil integrable functions are discussed here. We discuss the equivalence of the ap?Henstock-Kurzweil integral on a topological vector spaces and the vector valued ap?Henstock-Kurzweil integral. Finally, several convergence theorems are studied.
Barreledness in locally convex direct sum cones
Authors: Motallebi M.R.
Published: April 2023

We investigate the direct sum of barrel subsets in locally convex cones and
present necessary and sufficient conditions for the barrelness of subsets in
direct sum cones. This leads us to prove a direct sum locally convex cone
topology is barreled if and only if its components are barreled.