bluuebunny/crossref_metadata_2025 huggingface dataset:
Warburg Effect-Promoted Exosomal Circ_0072083 Releasing Up-Regulates Nango Expression Through Multiple Pathways and Enhances Temozolomide Resistance in Glioma
Authors: Ding Chenyu , Yi Xuehan , Chen Xiangrong , Wu Zanyi , You Honghai , Chen Xiaoyong , Zhang Gaoqi , Sun Yong , Bu Xingyao , Wu Xiyue , Lin Zhangya , Gu Jianjun , Lin Yuanxiang , Kang Dezhi
Published: December 2020

BackgroundTemozolomide (TMZ) resistance limits its application in glioma. Exosome can carry circular RNAs (circRNAs) to regulate drug resistance via sponging microRNAs (miRNAs). miRNAs can control mRNA expression by regulate the interaction with 3’UTR and methylation. Nanog homeobox (NANOG) is an important biomarker for TMZ resistance. Hitherto, it is unknown about the role of exosomal hsa_circ_0072083 (circ_0072083) in TMZ resistance in glioma, and whether it is associated with NANOG via regulating miRNA sponge and methylation.MethodsTMZ-resistant (n=36) and sensitive (n=33) patients were recruited. The sensitive cells and constructed resistant cells were cultured and exposed to TMZ. circ_0072083, miR-1252-5p, AlkB homolog H5 (ALKBH5) and NANOG levels were examined via quantitative reverse transcription polymerase chain reaction and western blot. The half maximal inhibitory concentration (IC50) of TMZ, cell proliferation, apoptosis, migration and invasion were analyzed via Cell Counting Kit-8, colony formation, flow cytometry, wound healing and transwell assays. The in vivo function was assessed using xenograft model. The N6-methyladenosine (m6A) level was analyzed via methylated RNA immunoprecipitation (MeRIP). Target relationship was investigated via dual-luciferase reporter assay and RNA immunoprecipitation. Warburg effect was investigated via lactate production, glucose uptake and key enzymes expression. Exosome was isolated and confirmed via transmission electron microscopy and specific protein expression.Resultscirc_0072083 expression was increased in TMZ-resistant glioma tissues and cells. circ_0072083 knockdown restrained the resistance of resistant cells via decreasing IC50 of TMZ, proliferation, migration, invasion and xenograft tumor growth and increasing apoptosis. circ_0072083 silence reduced NANOG expression via blocking ALKBH5-mediated demethylation. circ_0072083 could regulate NANOG and ALKBH5 via targeting miR-1252-5p to control TMZ resistance. Warburg effect promoted the release of exosomal circ_0072083 in resistant cells. Exosomal circ_0072083 from resistant cells increased the resistance of sensitive cells to TMZ in vitro and xenograft model. Exosomal circ_0072083 level was enhanced in resistant patients, and it had a diagnostic value and indicated a lower overall survival in glioma. Conclusion﻿Exosomal circ_0072083 promoted TMZ resistance via increasing NANOG via regulating miR-1252-5p-mediated degradation and demethylation in glioma.
LINC00899 promotes osteogenic differentiation and alleviates osteoporosis via targeting miR-374a to regulate RUNX2
Authors: Gao Xiaoya , Xue Yun , Yang Kechun
Published: December 2020

Objective: This study aims to illustrate the underlying molecular mechanisms of long noncoding RNAs (LncRNAs) LINC00899 in osteoporosis.Methods: Real Time-quantitative Polymerase Chain Reaction (RT-qPCR) was used to examine the levels of LINC00899, miR-374a and RUNX2 in clinical tissues or human bone mesenchymal stem cells (hBMSCs). The interaction between miR-374a and LINC00899 or RUNX2 was predicted by starBase and verified by luciferase reporter assay and RNA binding protein immunoprecipitation (RIP) assay. Alkaline phosphatase (ALP) activity and Alizarin Red S (ARS) staining were also used to evaluate the osteogenic ability of hBMSCs.Results: The expression levels of LINC00899 were gradually increased, but miR-374a expression was decreased with the prolongation of osteogenic induction. In addition, the expression of LINC00899 was lowly expressed in osteoporotic patients’ bone tissues and knockdown of LINC00899 decreased the expression of osteogenesis-related genes. Moreover, LINC00899 was confirmed to inhibit miR-374a expression by direct interaction. Finally, we demonstrated that RUNX2 was a target of miR-374a, and the silencing of miR-374a partially abolished the inhibitory effect of LINC00899 knockdown on the expression of RUNX2, OPN and OCN.Conclusions: We demonstrated that LINC00899 facilitated the osteogenic differentiation of hBMSCs and prevented osteoporosis by sponging miR-374a and enhancing RUNX2 expression, which might provide a useful therapeutic strategy for osteoporosis patients.
Prevalence of Peripheral Neuropathic Pain among Adult Diabetic Patients (T2DM) with Peripheral Neuropathy and Quality of Life of the Patients with Peripheral Neuropathic Pain
Authors: Abu-Shennar Jawad Ahmad , Bayraktar Nurhan , Bebis Hatic
Published: December 2020

Aim The aim of the study was to assess the prevalence of diabetic peripheral neuropathic pain (DPNP) among adult patients suffering from type 2 diabetes mellitus (T2DM) with diabetic peripheral neuropathy (DPN) as well as to determine the quality of life of patients with DPNP.Materials and method The study designed in cross-sectional research model was conducted at the Jordanian Ministry of Health in Jordan, Amman during the period from 15 June 2019 to 5 October 2019. A total of 400 adult T2DM patients with DNP were recruited for the study. Data were collected by way of an assessment tool package, including descriptive data (demographics, anthropometric measurements, laboratory measurements, and clinical data), the Douleur Neuropathique4 (DN4) questionnaire, physical exam, Quality of Life Questionnaire (EQ-5D), and Numeric Pain Rating Scale (NRS). To analyze study data descriptive and inferential statistics were used.Results Results of the current study showed that the prevalence of DPNP among adult T2DM patients with DPN was high (47.8%). About half of the participants had mild or moderate pain with the most frequently reported symptoms of tingling and burning. Uncontrolled diabetes was found to be the main predictor of DPNP among patients with DPN. Participants who had DPNP reported having problems in connection with mobility, self-care, routine activities, discomfort, and anxiety or/and depression, and they had a significantly lower quality of life with poorer self-rated health status than those without DPNP. Besides, the effect of pain on their quality of life was found to be significant.Conclusion The study recommends, in accordance with the results, that strategies should be developed for an effective management of painful DPN with an integrated and interdisciplinary approach. Current clinical guideline recommendations should be followed to improve patient care and reduce the burden of the disease.
Evaluation of S2 alar and traditional S1 pedicle fixation for severe lumbar spondylolisthesis in different bone mineral densities: a finite element analysis
Authors: Wang Juehan , Chen Wei , Yang Xi , Zhu Ce , Ling Tingxian , Feng Ganjun , Song Yueming , Liu Limin
Published: December 2020

Purpose: Little is known about the biomechanical performance of L5-S2 alar internal fixation constructs after posterior lumbar interbody fusion. This study aimed to compare the biomechanical effect of L5-S1 internal fixation and L5-S2 alar internal fixation on severe lumbar spondylolisthesis. Methods: A normal male volunteer without a history of spinal disease was selected, lumbar CT data was collected. An intact L5-S2 three-dimensional finite element model was created by Mimics and Geomagic.Two kinds of fixation methods were reconstructed including (1) the L5-S1 screw fixation model and (2) the L5-S2 alar fixation model. The inverse repair was performed using Geomagic software, the internal fixation device was drawn using Creo software, and the model parameters were set and analyzed using ANSYS Workbench software. Results: The validity of the intact model shows that the ROM of the model is similar to that of a reported cadaveric study. The average stress of the L5-S2 alar internal fixation device was 86.9-111% higher(P＜0.001) than that of the L5-S1 fixation device when the bone of the S1 screw path reached the yield threshold. The maximal stress of the S1 screw in the L5-S2 alar fixation was significantly lower (P＜0.001) than it in the L5-S1 fixation when the stress exceeds the S1 bone yield threshold. When the S1 screw path bone yielded, the maximal deformation value of the S1 screw path was similar in both models (P>0.05), while the average deformation value of the S1 screw path in L5-S2 alar fixation was significantly higher (P＜0.01) than it in L5-S1 fixation. Conclusion: Extending fixation to the S2 wing can significantly improve internal fixation device stability and reduce the risk of intraoperative and postoperative fractures while avoiding injury to the sacroiliac joint, reducing the difficulty of surgery and the risk of injury to surrounding tissues. It is a reasonable plan for the treatment of moderate and severe lumbar spondylolisthesis with osteoporosis.
Dietary Intakes and Nutritional Status Among Migrant Children in Primary Schools: A Cross-Sectional Study
Authors: Zeng Jing , Shao Lijing , Li Yongjun , Yang Mei , Xiang Bing , Hao Liping , Yang Xuefeng , Cheng Guangwen
Published: December 2020

Background: Nutrition plays a crucial role in children’s growth and development, migrant children have their own characteristics in nutrition. The current study aims to assess the dietary status of migrant school-age children and underlying factors. Methods: A cross-sectional survey was carried out on migrant children in 25 classes with the 3rd to 6th grades from two primary schools by cluster sampling. Children’s 3-day 24-hour diet were recorded, the dietary intake of calories and nutrients were calculated by using the China Food Composition for each day, and were presented the average intake of the 3 day period. The assessment of energy and nutrient intakes by estimated energy requirement (EER) and estimated average requirement (EAR), respectively. The Dietary Guidelines for Chinese Residents and Chinese Dietary Reference Intakes were used as evaluation standards to assess the dietary intakes and nutritional status of these children.Results: Participants included 752 migrant children aged 9-12y (430 boys and 322 girls). Deficiency proportions of energy and protein were 46.1% and 40.1% for boys, 44.4% and 65.1% for girls. Energy supply proportions of macronutrients (protein, fat, and carbohydrate) in boys were 12.4%、28.8%、58.8%, those of girls were 11.1%、28.6%、60.3%. The insufficiency proportions of vitamin A, B vitamins, calcium, zinc and selenium were considerably serious (>60%). In dietary pattern, intakes of cereal, poultry and edible oil were relatively adequate, but milk, fish, eggs and soybean products were seriously inadequate. Conclusions: Characteristics such as unreasonable dietary pattern, relative lack of energy and nutrients, and excess snack intake coexist, it is necessary to carry out nutrition intervention to help migrant children to balance the diet and rectify the deficiencies.
KENAKALAN REMAJA KAUM SANTRI DI PESANTREN ‎(TELAAH DESKRIPTIF-FENOMENOLOGIS) ‎
Authors: Rahmatullah Azam Syukur
Published: December 2020

Abstrak: Penelitian ini bertujuan untuk mengetahui lebih dalam kenakalan-kenakalan apa saja yang terjadi di pesantren, dan hasil penemuan penelitian dapat mengklasifikasikan jenis-jenis kenakalan remaja kaum santri di pesantren. Jenis penelitian ini adalah penelitian kenakalan remaja terjadi di manapun dan dalam situasi apapun, termasuk di ranah pesantren. Beberapa penelitian menunjukkan bahwa perilaku-perilaku santri terkadang nganeh-nganehi dan bisa dikatakan menyimpang dari aturan kepesantrenan. Hal yang demikian adalah fakta dan nyata. Oleh karena itu, dalam hal ini peneliti berupaya untuk menelaah lebih dalam lagi perihal kenakalan-kenakalan remaja santri yang terjadi di pesantren. Tujuan dari literatur dan sifat dari penelitian ini adalah deskriptif kualitatif dan eksploratif yang mengkaji secara mendalam untuk menemukan hal-hal baru, yang kaitannya dengan kenakalan remaja kaum santri di pesantren. Sedangkan analisisnya menggunakan studi content analysis yakni penelitian yang bersifat pembahasan mendalam terhadap isi suatu infomasi tertulis. Hasil penelitian menunjukkan bahwa penyebab kenakalan-kenakalan remaja santri antara lain dilihat dari individu santri, lingkungan pesantren dan lingkungan relationship antar santri. Adapun tingkatan kenakalan remaja santri terbagi menjadi tiga yakni kenakalan tingkat bawah, sedang dan tinggi. Sedangkan penanganan yang dilakukan pesantren untuk mengatasi kenakalan remaja santri menggunakan pendekatan antara lain pendekatan hati ke hati (touching heart), pendekatan spiritual-religius, sampai pada pendekatan yang berbasis kedisiplinan yang sifatnya tegas sesuai aturan yang berlaku.
PENGEMBANGAN MODEL PEMBELAJARAN BERBASIS ‎TEKNOLOGI INFORMASI PADA PESANTREN DI ‎SUMATERA BARAT
Authors: Rajab Rajab , Zulmuqim Zulmuqim , Hidayatullah Rully
Published: December 2020

Abstrak: Penelitian ini bertujuan untuk mengembangkan proses pembelajaran berbasis teknoligi informasi di pesantren, medorong pendidik/guru di pesantren menggunakan teknologi informasi dalam proses pembelajaran. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dan dipadukan dengan kajian perpustakaan, sehingga akan mendapatkan konsep dan kajian yang mampu membawa pesantren ke era revolusi industeri 4.0. Permasalahan yang terjadi di pesantren antara lain proses pembelajaran di kelas masih terpusat pada guru, sumber pengetahuan utama masih berasal dari guru dan literasi yang berkembang masih calistung (membaca, menulis dan berhitung). Hasil penelitian antara lain; pimpinan pesantren dapat melaksanakan pembelajaran berbasis teknologi informasi mengunakan Learning Management System (LMS), seperti; Google Classroom, Zoom Clouds Meeting, Schoology dan LMS lainnya. Sehingga proses pembelajaran tidak hanya terpusat pada guru tetapi terpusat pada peserta didik/santri dan literasi yang digunakan adalah literasi data, literasi manusia dan literasi teknologi.

Kata Kunci:     Revolusi Industri 4.0, pembelajaran, teknologi informasi.
Capital structure and profitability: the case of Nigerian deposit money banks
Authors: Olubukola Otekunrin Adegbola , Ikechukwu Nwanji Tony , Eluyela Damilola , Kolawole Olowookere Johnson , Gabriel Fagboro Damilola
Published: December 2020

This paper aimed to empirically examine the extent to which capital structure impacts the profitability of Nigerian Deposit Money Banks considering the profitability of eight Nigerian Deposit Money Banks from 2003 to 2018 (16 years). A descriptive research design was adopted for this study, and data were analyzed using regression. The study used secondary data obtained from published annual reports of selected Nigerian Deposit Money Banks on the Nigerian Stock Exchange (NSE) for four years (2003–2018). The study concluded that the indicators used to measure capital structure (debt-equity ratio and leverage ratio) and profitability (returns on equity) had a negative relationship. This means that the use of debts mixed with equity (debt-equity ratio and leverage ratio) in improper proportion as financing methods can negatively affect profitability. Hence, there is a need to identify the optimal mix of capital structure (debts mixed with equity) that maximizes profitability, as well as firm and shareholder value with minimum agency costs as suggested by the trade-off theory and agency theory, respectively. The alternative is to give preference to retained earnings (internal source of finance) as funding source.
AcknowledgmentAll researchers and non-researchers that contributed to this paper are highly appreciated.
Voluntary health insurance as a source of funding for the health care system: the world’s experience and Ukraine
Authors: Zhuravka Fedir , Zhuravka Olena , Bondarenko Eugenia
Published: December 2020

In the conditions of insufficient budgetary financing of the health care system and low quality of medical care in the state medical establishments of Ukraine, the importance of extra-budgetary sources of financing becomes increasingly relevant. One such source is voluntary health insurance. The aim of the paper is to compare the state and structure of medical financing in developed countries and in Ukraine, to study the global experience in the functioning of the voluntary health insurance market, and to calculate the potential capacity of the voluntary health insurance sector in Ukraine. For mathematical calculations, 20 absolute indicators of the state of the voluntary health insurance sector, as well as macroeconomic indicators, were used. The annual values of absolute indicators for the period 2010–2019 were used in forming the array of input data. Based on the experience of foreign countries, the paper substantiates the development of the voluntary health insurance in Ukraine as an extra-budgetary source of health care funding. The capacity of the voluntary health insurance sector was defined by the authors as the maximum possible amount of insurance premiums that insurers can receive in the process of selling voluntary health insurance products. The calculations made it possible to conclude that the voluntary health insurance market in Ukraine has the potential for development, as evidenced by the predominance of the potential capacity of the voluntary health insurance segment over its real indicator.
Applied aspects of the geochemical ecology of microorganisms used for solving ecobiotechnological tasks
Authors: Ermakov V.V. , Guseva T.V. , Kovalsky Yu. V. , Panfilov V.I.
Published: December 2020

The article presents a new view on opportunities on using microorganisms for achieving a wide range of biotechnological and environmental objectives. Examples of recent innovations in applying bio-products based on living cells of microorganisms for remediating oil polluted soils and enhancing soil fertility are given. The significance of microbiological solutions with regards of achieving objectives of the National Project "Environment/Ecology" is underlined. Perspectives and effectiveness of technologies applying microbial biomass enriched in microelements for correcting microelementoses and preventing biogeochemical endemic diseases is demonstrated.

biogeochemistry, biotechnology, geochemical ecology, microelementosis, effectiveness of application, microbial bio-products.
Influence of Physicochemical Properties of Fluoroquinolones on their Interaction with Human Serum Albumin
Authors: Kopnova T.Yu. , Yakupova L.R. , Le-Deygen I.M. , Kudryashova E.V.
Published: December 2020

It has been shown on the example of ciprofloxacin and levofloxacin that fluoroquinolones are able to interact with human serum albumin even at low molar ratios. A fivefold molar excess of fluoroquinolone quenched the protein fluorescence until its completely disappeared. The data of fluorescent analysis led to the conclusion that the relationship between the protein and hydrophobic ciprofloxacin is based on hydrophobic bonds, while less hydrophobic levofloxacin interacts with serum albumin via electrostatics. It was established that kinetics of drug release from the protein--fluoroquinolon complex depends on the Ganesh hydrophobicity parameter of the antibiotic. The obtained results are important for the rational design of new drugs and the prediction of their pharmacokinetic characteristics.

human serum albumin, fluoroquinolones, fluorescent spectroscopy
TANTANGAN INDEPENDENSI MEDIA DALAM PEMILU: KASUS KOMPAS.COM
Authors: Khotimah Nurul
Published: December 2020

The aim of this study is to describe media ideology and construct media independence in the 2019 political year. Ideology has a major influence on the determination of media content. It is as if the general election democracy party cannot be separated from the mass media, so that the reporting of events "attacking each other" by the candidate pair cannot be avoided in the general election contestation. The object of the study was Kompas.com reporting on time limitations during the 2019 presidential and vice presidential election campaign. The research method used was qualitative library research. Data collection techniques using documentation. The results showed that the challenge of media ideology in maintaining the independence of media coverage in the political year must use the principles of independence. They are the presence or absence of opinion, personalization, sensation, stereotype, linkage, and accuracy in reporting.
KOMUNIKASI PROFETIK RASULULLAH DALAM MEMBANGUN UKHUWWAH DI MADINAH
Authors: Mukoyimah Mukoyimah
Published: December 2020

Communication is a core activity in every interaction. Every interaction contains a vision, so does the Prophet Muhammad. as a communicator. Prophetic communication of the Prophet needs to be an example/uswatun hasanah in building ukhuwwah. This study aims to provide an understanding back to the communicator/da'i of the current era about what prophetic communication should be done in facing of the complex conditions in the middle of the communicant. This research is a qualitative library research on hadiths delivered by the Prophet in Medina. While the data collection techniques is documentation and the data analysis used is interpretation. The results of this study shows the prophetic communication built on the personal and communal understanding of communicant, giving rise to the right method and way to build ukhuwwah in Medina. The communication of Rasulullah was carried out clearly, repeating the message of da'wah, and adjusting the capability of the mad'u/communicant faced so that the Islamic community's ukhuwwah was well developed.

 
PELAYANAN KOMUNIKASI PERBANKAN DAN KEPUASAN NASABAH (PERSPEKTIF KOMUNIKASI ISLAM)
Authors: Perdana Dian Adi
Published: December 2020

This article explains about the optimization of banking communication services that causes customer (campus community) dissatisfaction. Banking communication services as the main source of the problem are not being able to use internet banking in banking services, the lack of employees at the nearest BTN operational office, payment schedules that are often delayed because of internet integrity connecting between the campus and the bank is broken and service dissatisfaction has not yet reached the remote area. This study is a qualitative research by doing interview, observation, and documentation in data collection. The interactive analysis model is done in a descriptive qualitative manner and the data is presented with a SWOT analysis to determine the company's situation and strategy. The conclusion is the component of customer satisfaction in the form of: responsiveness, compliance, empathy, tangible, reliability and assurance which are elements of patterns of improvement in communication services have a positive influence on customer satisfaction in using banking services. This must be started and addressed by prioritizing customer needs. Researchers found that service influences customer satisfaction, which means that the greater the influence of service, the greater the satisfaction achieved by these customers, and these efforts continue to be carried out by BTN in maintaining customer trust in the company. Another thing is the need to optimize the strength they have to respond to opportunities that arise from external companies.

 
HOAKS DAN ALQURAN: UPAYA MEMBANGUN PERADABAN KRITIS DALAM MENERIMA BERITA DAN ADAB DALAM BERKOMUNIKASI
Authors: Wirdiyana Salwa Sofia
Published: December 2020

This paper seeks to parse the solution to the problem of hoax from the perspective of Quranic interpretation holistically and comprehensively. This study is a qualitative research by reading the  relationship (munasabah) between verses about  hoax in the Holy Quran that are represented by the terms ifk, fa>siq, muna>fiq, murjifu>n, and tabayyun. After reading the verses related to the term, it was concluded that hoax news can be minimized by critical thinking, having emotional maturity, performing tabayyun, and broadening insight. In addition, the Holy Quran also teaches good communication ethics, namely qaulan sadi>dan (correct speech), qaulan bali>gan (good words that leave an imprint on the soul), qaulan maisu>ran (proper speech), qaulan layyinan (soft words), qaulan kari>man (noble words), and qaulan ma'ru> fan (good words).

 
OTORITAS KEILMUAN GUS IZZA SADEWA DAN MEDIA BARU (PUTRA KH. IMRON JAMIL JOMBANG)
Authors: Abshor M Ulil
Published: December 2020

The study aims to uncovered the facts behind the scientific authority that was showed by Gus Izza Sadewa (the son of KH. Imron Jamil Jombang), who was only 15 years old and was able to present a scientific identity and sufism practices that was very beneficial. The author focuses on YouTube's new media as a shaping of scientific authority in the cyberculture world. The author analyzes the content analysis of some YouTube videos about Gus Izza. The content provided is manifested in aspects of contextual sufism. According to Heidi A. Campbell, there are 4 things that influence a religion or a text ideology, namely hierarchy (value), structure, ideology, and text. The results obtained from several segments of the hierarchy or values formed in the self of Gus Izza, he has Sufism and mature scientific authority, which can be proven by giving explanations about monotheism, the most important in looking for mursyhd-teachers, faith, actualizing worship that applied in daily life. All of those have the main orientation in the virtue ethics (akhlaq al-karimah).
Kebijakan redaksi media di Indonesia dalam pemberitaan haji tahun 2020
Authors: Ningsih Ida Nuraini Dewi Kodrat , Prastya Narayana Mahendra
Published: December 2020

There was uncertainty in Hajj 2020 due to the Covid-19 pandemic. Before the Kingdom of Saudi Arabia's government announced the limitation of Hajj 2020, several countries including Indonesia has decided not to cancel the hajj trip. In dealing with uncertain information, the public needs valid information because uncertainty leads to speculations. In this situation, the media has a vital role in giving valid and verified information. This article aims to know how Indonesia media editorial policy in hajj 2020 news coverage. The editorial policy consists of the news theme, news sources, and news reporting technique. The data collection use interview with five informants from different media. The results before the official announcement, media deliver the news about the future of Hajj 2020 and the Indonesian government plan in dealing with the situation. After the official announcement both from Indonesia and Saudi Arabia gov’t, the media deliver information about the procedure to refund the hajj fee. News sources are the Ministry of Religion of the Republic of Indonesia, pilgrims, and travel agencies, and umrah. News reporting techniques use teleconference, citing information from authority's official websites, and citing news from other news agencies.
Editorial
Authors: De Oliveira Lima Samuel Anderson
Published: December 2020

Editorial do número 2 do volume 5 da Revista Odisseia.
Por uma epistemologia da sexualidade na literatura contemporânea
Authors: Silva Claudicélio
Published: December 2020

O artigo propõe-se a discutir o esboço de uma epistemologia da sexualidade aplicada aos estudos da literatura, sobretudo a que se inscreve na contemporaneidade, tendo como pressupostos teóricos dois conceitos de Foucault: episteme, formulado em As palavras e as coisas (1966), e dispositivo, apresentado em História da Sexualidade I (1976). O estudo apresenta um vocabulário conceitual que têm servido de ferramentas para a análise das personagens no campo da ficção. Desse modo, interseccionalidade, masculinidade/virilidade, feminino, identidades de gênero, queer, performatividade e heteronormatividade compulsória são conceitos carregados de tensões, tanto discursivas quanto políticas.
Escrita não criativa e neuro-estética: conceitos, aspectos, possibilidades
Authors: Santos Sergio Marcone
Published: December 2020

Uma das premissas da escrita não criativa prevê que o procedimento (o copie e cole) seja tão ou mais importante que o resultado final da obra, legando à audiência o entendimento que melhor lhe aprouver (GOLDSMITH, 2015). Queremos discutir formas desse “entendimento”, considerando alguns conceitos da neurociência, em particular os que se detêm sobre a relação mente, corpo e estética – a neuro-estética. Com o desenvolvimento das ciências cognitivas, passou-se à discussão dos processos artísticos, na qual termos como “emoção”, “sentimento estético”, “empatia” etc., foram vistos como objetos que funcionam segundo regras identificáveis na naturalização da relação espectador-obra-autor (COUCHOT, 2018). Exporemos o “não original” a isso, arriscando comentar obras como Traffic (2007), Trânsito (2016) e Hillary: The Hillary Clinton emails (2019), de Kenneth Goldsmith, Statement of facts, de Vanessa Place (apud Goldsmith, 2015), e a instalação Uma e três cadeiras (1965), de Joseph Kosuth.
Historiografia literária brasileira hoje: hibridismo e multiplicidade
Authors: Pereira Helena
Published: December 2020

A história da literatura brasileira registrada em compêndios e obras de referência apresenta, em sucessivos movimentos, os escritores, as obras e suas circunstâncias, desde o período colonial até o final do século passado. A partir deste último período, todavia, nota-se nessas obras uma certa incompletude, decorrente, entre outras razões, do tempo necessário aos procedimentos de seleção, análise e interpretação de dados sobre a variada e volumosa produção literária. Decorridos já dois decênios do século XXI, propõe-se neste artigo a retomada e a complementação das tendências da produção recente, tais como o hibridismo, a multiplicidade e a heterogeneidade, em suas relações de continuidade ou ruptura com a produção do século passado. Espera-se reunir neste texto subsídios para complementar a construção da historiografia literária brasileira.
A hora da aula e o tempo da história nos estudos literários: uma entrevista com Eduardo Sterzi
Authors: Oliveira Eduardo Jorge de
Published: December 2020

A entrevista com Eduardo Sterzi, Professor de Teoria Literária na Universidade de Campinas – UNICAMP, expõe alguns aspectos da aula de literatura e do tempo da história literária. Essa conversa aspectos que conectam a literatura, seus saberes diretos e indiretos, relações de força entre história e historiografia literária além da aula [de literatura] como um acontecimento único, uma força além do conteúdo ou das técnicas pedagógicas de ensino.
AS PESSOAS “PERIGOSAS” E “SUSPEITAS” E AS PESSOAS “CRIMINOSAS” NAS NORMATIVAS MIGRATÓRIAS BRASILEIRAS
Authors: Sestokas Lucia
Published: December 2020

No presente artigo, desenvolvo argumentos iniciais sobre como os deslocamentos no Brasil são construídos e geridos a partir de noções de “pessoa perigosa” ou “pessoa suspeita”, mas também a partir de “pessoa criminosa”. Para tal, apresento um breve histórico de tais categorias nas normativas brasileiras, reavivadas pela publicação da Portaria 666 em 2019, assim como uma análise etnográfica da audiência criminal de uma pessoa não-brasileira processada por tráfico de drogas internacional em São Paulo. Pretendo assim trazer para o debate o papel de agentes e instâncias estatais na construção e operação de tais noções.
DECOTE E HIJAB NAS NOTAS DA ETNOGRAFIA COM MULHERES DO CONFLITO SÍRIO NO BRASIL
Authors: Souza Mirian Alves de
Published: December 2020

Este artigo pretende contribuir para a produção antropológica sobre refúgio. A partir de uma etnografia com mulheres refugiadas do conflito sírio, o texto discute certos discursos humanitários. A etnografia é a metodologia adotada. O trabalho de campo foi desenvolvido no Rio de Janeiro e em São Paulo, entre 2015 e 2018. As narrativas apresentadas buscam romper com uma imagem visual das mulheres refugiadas como eternamente vulneráveis ou oprimidas pela “cultura”, reconhecendo sua agência e descrevendo outras dinâmicas de poder interseccional.
TRILHAS FEMININAS: LEVES PEGADAS AO RITMO DA EXPROPRIAÇÃO NO CONTEXTO DO ALTO VALE DO JEQUITINHONHA MINEIRO
Authors: Silva Roberta Alves , Santos Rafael Pereira , Rech André Rodrigo
Published: December 2020

A mobilidade humana resulta de vários processos sociais e embora possa ser uma escolha, em muitas situações, ela é impositiva, compulsória e até violenta. Neste sentido, com base nas raízes históricas das mulheres do Vale do Jequitinhonha, o objetivo desse artigo é entender o papel social que a migração –sobretudo a migração feminina – tem tido na estruturação do modo de vida da comunidade Quilombola Monte Alegre, no município de Veredinha, em Minas Gerais. Para tanto, empregamos como metodologia neste processo a pesquisa participante, prezando pela participação efetiva dos sujeitos envolvidos. No decorrer deste trabalho, identificamos quatro formas de deslocamento feminino: a migração permanente com foco nos estudos, a migração para trabalho nas capitais-êxodo rural, a pendular e a sazonal. A migração foi identificada como uma forma de resistência da comunidade, mas ao mesmo tempo como um processo de transformação do modo de ser e de viver do povo, sendo o elemento responsável pela desterritorialização e reterritorialização dos comunitários, com a ressignificação social e feminina.
CORPOS EM CHOQUE NO “MUNDO”: SOBRE VIAGENS, FRONTEIRAS E OS DESAFIOS DO “ENTRE-LUGAR”
Authors: Bemerguy Telma de Sousa
Published: December 2020

Apostando na potência de uma escrita em ensaio, apresento aqui uma proposta de experimentação narrativa que possa conduzir o leitor a visualizar e sentir na própria etnografia a forma como nossas trajetórias, nossos corpos, nossas marcas e nossos medos delimitam pesquisas antropológicas sobre fronteiras, movimentos e experiências de mobilidade. Como podemos reinserir narrativamente nossos corpos no mundo? Como podemos fazê-lo, levando em conta tanto as “viagens” que nos constituem como sujeitas, quanto como mulheres antropólogas? Com essas ideias em mente, ao longo do texto, a descrição do choque entre diferentes corpos no mundo – os meu e os dos sujeitos com quem interagi em minha pesquisa de campo na Amazônia brasileira – será meu ponto de partida para conduzi-los dentre os elementos de uma teoria etnográfica genderizada/sexualizada dos movimentos pela fronteira em expansão.
Jardins de infância públicos estaduais na cidade de Campos dos Goytacazes na primeira metade do século XX
Authors: Monção Vinicius , Martínez Silvia Alicia
Published: December 2020

O artigo tem como objetivo mapear os jardins de infância públicos, criados e mantidos pelo governo estadual entre as décadas de 1920 e 1940, na cidade de Campos dos Goytacazes, localizada na região norte do estado do Rio de Janeiro. Foram analisados os mapas de frequência escolar e dos adjuntos existentes no Fundo Departamento de Educação do Arquivo Público do Estado do Rio de Janeiro. As análises se apoiaram nas proposições oriundas da História Social da Educação. Tal perspectiva está interessada em um possível afastamento de uma postura paternalista para responder sobre a implementação da pré-escola pública. Como resultado, percebe-se que a criação dos jardins de infância estava relacionada com a renovação da instrução pública e especialização no magistério público.
Cenzura wypowiedzi dotyczących islamu w Europejskim Trybunale Praw Człowieka: uderzający przypadek sprawy E.S. przeciwko Austrii
Authors: Puppinck Grégor
Published: December 2020

Europejski Trybunał Praw Człowieka nierzadko wydawał wyroki chroniące osoby, którym zarzucano bluźnierstwo zwłaszcza przeciwko religii chrześcijańskiej. Tymczasem postanowił utrzymać w mocy potępienie przez austriackie sądy decyzji skazującej za bluźnierstwo Elisabeth Sabaditsch-Wolff, która publicznie opisała znany fakt zawarcia przez Mahometa ślubu z nieletnią dziewczynką jako pedofilię. Sąd austriacki oficjalnie wyznał, że musiał te słowa potępić w imię pokoju religijnego. ETPC podtrzymał ten wyrok w imię tolerancji religijnej, niejako zawieszając wcześniejsze orzecznictwo i nie cenzurując wszelkie wypowiedzi krytykujące islam, choćby były one zgodne z prawdą. To naruszenie wolności wypowiedzi usprawiedliwia się nowym pozytywnym obowiązkiem nałożonym na Państwa przez Trybunał, a polegającym na „zapewnieniu pokojowej koegzystencji wszystkich religii i tych, którzy nie przynależą do żadnej grupy religijnej, poprzez zapewnienie wzajemnej tolerancji”. W ten sposób każda wypowiedź, nawet prawdziwa, może zostać uznana za naganną jako wyraz nietolerancji religijnej, jeżeli mogłaby prowadzić do napięć społecznych.
Historyczny rozwój programów działań na rzecz środowiska w Unii Europejskiej
Authors: Kosior Monika
Published: December 2020

The intensive economic development within EU member countries leading to a significant environment pollution invoked in 70’s a strong need to introduce uniform legal regulations of a common pro-ecological policy, therefore, during the Conference in Paris in 1972, the European Commission was obliged to work out particular programs for the environment protection, realization of which was intended to be done in subsequent time intervals. Incorporation of the first two programs led to formulating principle rules of EU ecological policy that up till now are general determinant of environmental protection in Europe. As a result of the following two programs, a complex system of legal and financial protective instruments along with the system for environment screening was worked out. That time, also two important ecological rules were formulated: durability of natural capital, and ensuring the appropriate environment conditions for further generations, these rules are considered as a basis for sustainable development accepted as one of the main targets of EU ecological policy, the continuation of activities for sustainable development can be also found in subsequent programs (including the VI Program planned for realization by 2010) focused on the search for such legal and institutional solutions that would guarantee the equilibrium between the economic development of particular EU members and the improvement of environment status. Here performed analysis of programs for the environment protection allows for presenting not only the following stages of the ecological law formation in European Union but also underlining their role in shaping and realization of the sustainable development concept.
Analiza wpływu budowy i eksploatacji infrastruktury drogowej na czynniki abiotyczne i biotyczne środowiska
Authors: Biernat Krzysztof , Syta Anna
Published: December 2020

The expansion of the road network in Poland and in world constitutes a considerable risk for the natural environment, this article is showing the most important effects of road investments, for example: pollutants of atmospheric air, the noise and vibrations, pollutants of waters and soils, the fragmentation of the space and the decline of the landscape. Everything is leading it for destroying the environment in which we live. Describing all threats to the environment with themselves a structure and an exploitation of roads are bringing which, is practically impossible, the man in the last years very much is interfering in the nature, instead of to protect it for next generations, therefore designers and entrepreneurs should concentrate on eliminating negative effects of construction and the more late exploitation of roads and for improvement in their technical state.
Prośrodowiskowe kształtowanie terenów zieleni - propozycje dla dzielnicy Ursynów m.st. Warszawy
Authors: Staroszczyk Justyna , Skowroński Antoni
Published: December 2020

It is well known that green areas are a significant component of urban environment. Plants influence urban conditions in many ways; they have a positive effect on both people’s health and environmental issues, there are many reasons why the proportion of green areas in cities should be increased. It is important to take advantage of plant properties and suitable methods of shaping green areas to benefit nature.

The article emphasizes the importance of comprehensive environmental protection. It presents selected methods of shaping green areas and nursing plants, which are in common use in Western Europe and USA, but are under-used in Poland, the main aim of the article is to propose solutions which allow to shape green areas in the Ursynów district of Warsaw in favor of environmental protection e.g. in a way that makes it possible to preserve biodiversity or reduce drink water use.
Institute of Ecology and Bioethics of the Cardinal Stefan Wyszyński University
Authors: Sandner Jan
Published: December 2020

Preparation of appropriate methodology for teaching about natural resources in accordance with the concept of holistic education is currently becoming one of our major goals. Achievement of these goals is indispensable in the perspective of objectives set within the framework of sustainable development, this article is a general overview of results of studies carried out in 2007 on the condition of holistic environmental education among students of the Institute of Ecology and Bioethics at the Stefan Wyszyński University, the s e studies have strongly emphasized the issue of distinguishing the mereological approach and the holistic approach to the natural environment with the use of modern methods of estimation.
Evaluation of Escape Route Design in Public Multi-Storey Housing in Malaysia for Elderly Occupants
Authors: Hanapi Nurul Liyana , Sh Ahmad Sabarinah , Abd Razak Azli
Published: December 2020

Public multi-storey residential buildings in Malaysia are dependent on the passive design approach to ensure maximum safety during an emergency. Elements of escape route design include corridors, exits and staircases. This paper evaluates the escape route distance and duration for the elderly to evacuate the building to safety using Pathfinder simulations. The results show that the staircase has a significant contribution towards providing fast evacuation. Meanwhile, varying the width of the exit doors and corridors had minimal impact on evacuation. On average, the elderlies took longer to evacuate due to their slow speed of movement and limited physical capability.
Keywords: Multi-Storey, Escape Route Design, Evacuation, Simulation
eISSN: 2398-4287 © 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/110.21834/ebpj.v5iSI2.2521.
Spatial analysis of toxoplasmosis through EcoHealth approaches using GRA-1 recombinant: case in Sleman, Yogyakarta
Authors: Fihiruddin Fihiruddin , Artama Wayan Tunas , Widartono Barandi Sapta
Published: December 2020

Toxoplasmosis is an obligate intracellular zoonotic parasite caused by Toxoplasma gondii that can infect all warm-blooded animals including humans. Prevalence of toxoplasmosis varies depending on climate, geography, and the presence of cats in an area. This study aimed to identify the prevalence and distribution of toxoplasmosis in Sleman, Yogyakarta through EcoHealth approaches. A total of  385 blood samples were collected from residents in the district of Sleman. Seven people from 55 villages were selected for blood sampling using a cluster method. The collected serums were tested by ELISA using recombinant Granule 1 protein (GRA-1) as  coated antigen. Data on altitude and coordinates of sampling sites were collected using GPS.  instruments, soil surface temperature in Sleman was obtained by satellite imagery, and cat population in residential areas was determined by questionnaire. The prevalence of toxoplasmosis in Sleman was 58%, of which distributed around rivers and in cattle pens. Based on altitude and temperature, toxoplasmosis cases were found the highest at 0-150 m (66.3%) and at temperatures of 26-30°C (66.4%). Areas with large numbers of cats had toxoplasmosis prevalence of 75.8% while areas with moderate and few cats were 56.5% and 49.0%, respectively. Thus, differences in the prevalence of toxoplasmosis at settlement were found based on altitude, soil surface temperature, and cat populations.
In vitro expression of the recombinant fusion protein of Newcastle disease virus from local Indonesian isolates by using a cell-free protein expression system
Authors: Haryanto Aris , Wihadmadyatami Hevi , Wijayanti Nastiti
Published: December 2020

The aim of this work was the in vitro expression of the recombinant fusion (F) protein of Newcastle disease virus (NDV).  The pBT7-N-His-Fusion-NDV expression plasmid which carries the recombinant F protein encoding gene from local Indonesian isolates, was prepared and transformed into E. coli BL21 (DE3). To detect bacterial colonies carrying the recombinant plasmid, a restriction endonuclease analysis was performed using the EcoRI restriction endonuclease. These results showed that the pBT-N-His-Fusion-NDV plasmid was successfully isolated with a size of 4.601 bp, and three recombinant plasmids carrying the gene coding for the recombinant F protein of NDV were obtained. Selected recombinant plasmids were then in vitro by using a cell-free protein expression system followed by visualization of the recombinant F protein on a 12% SDS-PAGE gel both by Coomassie Brilliant Blue staining and Western blotting. Recombinant F protein was successfully in vitro expressed by using a cell-free protein expression system as indicated by a specific single protein band with a molecular mass of 25.6 kDa.
Volunteering and the Destinations: Socialisation and Interaction
Authors: Wen Julie Jie
Published: December 2020

Volunteering has been part of the growing social and economic phenomenon because of the belief that it delivers positive effects for the stakeholders involved. This paper undertakes analysis of the impacts of the Sunflower (xiangrikuei) volunteering program. The research attempts to understand the views of the volunteers, organisers, and destination representatives from interviews, focus groups and observation. The research confirms that while volunteers and organisers do benefit from the experience, the impacts of volunteering on the destinations present a complex mixture of results. While destinations do express their benefits from working with volunteers who bring different skills and influences, they are concerned that volunteers working for a short period of time do not bring enough positive changes but rather disturb the normal local arrangement. Communication may be challenging, and conflicts may arise between volunteers and some local people. The research provides insights for improving the benefits for destinations related to volunteering.
Etnografía histórica de la migración croata y chilota en la fiebre del oro en Porvenir, Tierra del Fuego, Chile 1930-1990
Authors: Saldivar Arellano Juan Manuel
Published: December 2020

The article shows ethnographic findings about gold fever and the incorporation of Croatian pirquineros and chilotes in the vicinity of the Baquedano de Porvenir cordillera, Chilean Heart of Fire. They were two stages of gold abundance developed between the decades of 1983-1905 and 1930-1990. The first began with the discovery of the mineral through expeditions that ran aground on austral beaches, then the territories were exploited by Julio Popper, who formed the Anonim Company of Lavaderos of Gold of Sud, tracing the gold route from Cabo Vírgenes to Punta Arenas, Navarino Island, Bahía Aguirre, Sloggett, Nueva and Lennox, being the Páramo in San Sebastián, its main operation center. The second was related to local miners (Croats and Chilotes) who continued with the exploitation in an artesanal way in the deposits of the Fuegian mountain range. The gold rush contributed to the foundation of Porvenir, highlighting investments in general lines, hotels and leisure as part of the peripheral economies, in addition to the growing wool industry that continued as a durable economy.