bluuebunny/crossref_metadata_2025 huggingface dataset:
Rancang Bangun Alat Pencetak Rempeyek Bulat Diameter 90mm
Authors: Porawati Hilda , Rifa'i Ahmad Imam , Reforandika Gentur Pressa , Ramadhan Fahrur Razi
Published: October 2022

Produk rempeyek sangat disukai masyarakat sehingga banyak pengolah yang memproduksinya yang dijual diberbagai tempat mulai pasar tradisional maupun pasar modern. Penerapan teknologi tepat guna untuk peningkatan kapasitas produksi sangat dibutuhkan oleh Usaha Mikro Kecil dan Menengah (UMKM). Dalam penelitian ini rancang bangun alat penggoreng rempeyek telah dibuat dengan menggunakan cetakan bulat yang memiliki 10 cetakan rempeyek dengan sistem pengungkit pegas yang dioperasikan secara manual. Hasil penelitian menunjukkan bahwa hasil penggorenggan memiliki diameter 90 mm dan ketebalan cetakan 2 mm dan berjumlah 10 buah keping dalam sekali proses penggorengan. Penggunaan material stainles pada cetakan menyebabkan adonan lengket pada tahap penggorengan rempeyek.
Cheiloscopy- An Important Technique in Forensic Science for Identification: A Review
Authors: Ambrish Kaushal  , Priyanka Chhabra
Published: October 2022

Background: The concept of lip prints is clear from previous literature review that this evidence can be used for forensic purpose. While accepting that a body of data existed regarding the individuality of lip pattern, there is no credible research on the stability of the lip detail over time. The timescale in question could be measured in weeks and months or years. The former would be used in police investigations and the latter can be used by geneticist.
Surgical Venous Ablation in Varicose Veins Lower Extremity under Sonographic Guidance
Authors: Deepak Tolia  , Jitesh Tolia2
Published: October 2022

ntroduction: The EVLA method can be applied in approximately 70% of the patients with complaints of varices. The aim of this study is to assess the efficacy of the EVLA procedure in treatment of saphenous venous insufficiency and the resultant varicose veins.Materials & Method: Total of 100 patients were include in the study. The EVLA procedure was done using a 1470 nm laser diode by the Interventional Radiologist. The patients were evaluated clinically and by using colour Doppler before the procedure, two months and five months after the procedure.Results: The decrease in Venous clinical severity score and Venous disability score from the pre-procedural score to the second and fifth month scores (post procedure) was found to be statistically significant (p<0.05). Decrease in saphenous vein diameters from the pre-procedure measurement to the second and fifth month diameters (post procedure) at various levels as described was found to be statistically significant (p<0.05). Significant decrease in the number of patients with venous reflux was noted on fifth month follow-up after the procedure.Discussion & Conclusion: EVLA is a minimally invasive technique. EVLA results in irreversible damage to the vein which is ablated. The venous occlusion is mainly due to progressive fibrosis which causes obliteration of the vein rather than thrombotic occlusion. As this is a new technique, data regarding the long-term outcome of EVLA is required to confirm the durability of the procedure
The Effectiveness and Side Effects of Remdesivir in COVID-19 Patients with Pneumonia
Authors: Didik Hasmono  , Tis’a Febriyanti  , Eka Putri Nurhidayah  , Arina Dery Puspitasari  , Ruddy Hartono  , Mohammad Subkhan
Published: October 2022

Background: Remdesivir is one of the antiviral agents to treat COVID-19 infection. It has an antiviral activity directly related to activation of pro-inflammatory responses, causing cytokine storm, multiorgan damage and mortality. With these potential activities, this study investigated the effectiveness and evaluated side effects of remdesivir used for COVID-19 patients with pneumonia. Methods: This cohort observational study collected data retrospectively from medical records of COVID-19 patients at Bhayangkara H.S Samsoeri Mertojoso Hospital, Surabaya. Patients who received remdesivir with loading dose (1 x 200 mg) IV had to follow maintenance dose (1 x 100 mg) IV. They were analyzed in three groups from October 2020 to February 2021. The data conveyed PCR/rapid Ag Swab, oxygen saturation, chest X-rays imaging, BUN, SCr, SGOT and SGPT.Result: A total of 60 patients were evaluated in three therapeutic groups, and the administration of remdesivir within 5-9 days was effective. Mostly, the patients (77%) had negative PCR/rapid Ag Swab; most of them (52%) had better oxygen saturation by supplementary oxygen therapy; more than a half had better chest X-rays imaging parameters (68%). Common side effects included an increase in SGOT (85.30%), SGPT (79.88%), BUN (74.23%), and serum creatinine (43.33%). Conclusion: The antiviral effect of remdesivir with loading dose (1 x 200 mg) IV needs to follow maintenance dose (1 x 100 mg) IV for 5-9 days. Hence, COVID-19 patients with pneumonia could have clinical improvement with increased level of liver and kidney function.
Digital Pocketbook Increase Mother's Knowledge about Covid-19 Transmission Prevention
Authors: Heni Heryani  , Lusi Lestari
Published: October 2022

Mothers and infants are at an increased risk of COVID-19 transmission. One of the preventive efforts that can be done is to use technology as a medium for health promotion, namely digital pocketbooks. Digital pocketbooks in accordance with the conditions of the COVID-19 Pandemic, where there is a policy of transmission efforts by limiting interaction and staying away from crowds. To determine the effect of using a digital pocketbook on a mother’s knowledge about reducing COVID-19 transmission to pregnant women, new mothers, postpartum mothers, and newborns. This study is a quasi-experimental study with an uncontrolled, pretest and posttest approach conducted at the Posyandu Tangkolo (Melati 2) in the Ciamis District. The sampling method used was purposive sampling, and a total of 30 samples. The digital pocketbook is given to increase mothers’ knowledge about to raise moms’ awareness of COVID-19 prevention strategies for pregnant women, mothers in labor, postpartum mothers, and infants. Questionnaires were used to measure the mother’s knowledge before and after being given a digital pocketbook. Paired T-test was applied for effect analysis.The results showed that there was a significant effect of digital pocketbooks on mothers’ knowledge about preventing the Covid-19 transmission in pregnant women, mothers giving birth, postpartum mothers, and newborns (p=0.000). Digital books make it easy for mothers to access information without having to leave the house, practically, whenever and wherever they want to open and read them easily.The use of digital pocketbooks can help mothers have a better understanding of how to prevent the transfer of COVID-19 to pregnant women, new mothers, postpartum mothers, and infants. It is recommended that digital pocketbooks can be used as a means to carry out health promotion.
Induction of spatial anxiety in a virtual navigation environment
Authors: Oliver Alice , Wildschut Tim , Parker Matthew O. , Wood Antony P. , Redhead Edward S.
Published: October 2022

Spatial anxiety (i.e., feelings of apprehension and fear about navigating everyday environments) can adversely impact people’s ability to reach desired locations and explore unfamiliar places. Prior research has either assessed spatial anxiety as an individual-difference variable or measured it as an outcome, but there are currently no experimental inductions to investigate its causal effects. To address this lacuna, we developed a novel protocol for inducing spatial anxiety within a virtual environment. Participants first learnt a route using directional arrows. Next, we removed the directional arrows and randomly assigned participants to navigate either the same route (n = 22; control condition) or a variation of this route in which we surreptitiously introduced unfamiliar paths and landmarks (n = 22; spatial-anxiety condition). The manipulation successfully induced transient (i.e., state-level) spatial anxiety and task stress but did not significantly reduce task enjoyment. Our findings lay the foundation for an experimental paradigm that will facilitate future work on the causal effects of spatial anxiety in navigational contexts. The experimental task is freely available via the Open Science Framework (https://osf.io/uq4v7/).
Quality Assessment and Content Analysis of Youtube Videos on Glaucoma Surgery
Authors: Dağdelen Kenan
Published: October 2022

The aim of this study is to evaluate the accuracy, quality and reliability of the videos on glaucoma surgery on YouTube which is an online video-sharing platform.The material has been obtained by a video search carried out on the Youtube -online video platform- with the keyword “Trabeculectomy” is kind of glaucoma surgery. A total of 44 videos for the keyword “trabeculectomy” were analyzed. When evaluated according to the exclusion criteria, a total of 10 videos were included in the analysis, and the 34 videos were excluded. Thus, after carving out the secondary data, a number of statistical analyses were performed namely Shapiro-Wilks, Kruskall-Wallis, Mann-Whitney U and Backward Linear Regression. In this framework, statistical analyzes were made via using the Stata software. Statistical significance value (threshold) was accepted as %10 (p<0.05). When the videos were evaluated according to the information content they provided, it was found that 5 videos had low quality information content, 4 videos had medium quality information content, 1 video had good quality information content. Moreover, it was statistically determined that the parameter affecting the number of views was the number of likes (p<0.05). This is the first study in ophthalmology to analyze publicly available online data evaluating glaucoma patients.YouTube videos are essentially insufficient as an educational material and an English source of information for the glaucoma surgery. Health professionals need to pay more attention to online platforms so that patients can access accurate information.
Pengaruh Pemberian Kompres Hangat Terhadap Penurunan Derajat Dismenore Pada Siswi Mas Ushuluddin Kota Singkawang
Authors: Martinus Sihombing Ferry Daniel , Gunawan Dahlan , Permata Putri Mutiara
Published: October 2022

Background:Dysmenorrhea is a gynecological problem defined as cramping pain in the lower abdomen that occurs during menstruation. Management of dysmenorrhea can use non-pharmacological therapy such as warm compresses. Warm compresses can cause blood vessel dilation (vasodilation) so that it can increase blood circulation, relieve ischemia in myometrial cells, decrease myometrial smooth muscle contraction, increase muscle relaxation and reduce pain due to spasm or stiffness. Methods: This research is a quantitative research. This research method is pre-experimental with one group pretest-posttest design. The sampling technique is purposive sampling. The sample in this study were 74 students who experienced dysmenorrhea in January 2022. Data was collected using the Numeric Rating Scale (NRS) dysmenorrhea pain scale observation sheet before (pretest) and after (posttest) warm compresses were given. Data were analyzed using the Wilcoxon Signed Rank Test. Results: After the Wilcoxon Signed Rank Test, the results showed a p-value of 0.000. The p value is smaller than the significant value or Sig. (2-tailed), which is 0.05(p < 0.05) so that H0 is rejected, and Ha is accepted. Conclusion:Based on the results of this study, it can be concluded that there is an effect of giving warm compresses to the decrease in the degree of dysmenorrhea in students of MAS Ushuluddin Singkawang City in 2022.
Hubungan Hiperglikemia Reaktif dengan Prognostik Stroke Iskemik di Rumah Sakit Budi Kemuliaan Kota Batam
Authors: Hendra Putra , Batubara Syaiful , Auliannisa Dianty
Published: October 2022

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Hubungan Hiperglikemia Reaktif dengan Prognostik Stroke Iskemik di Rumah Sakit Budi Kemuliaan Kota Batam
Authors: Galindra Yusmahenry , Sahreni Sukma , Andjellya Zilvina
Published: October 2022

Background:Stroke is the process of death from brain cells due to lack of oxygen supply to the brain. An ischemic stroke is an episode of neurological dysfunction caused by focal, spinal, or focal cerebral infarction. Stroke is the second leading cause of death in the world and the third cause of disability in the world. There are many factors that are thought to play a role in the onset of stroke, one of which is hyperglycemia. The purpose of this study is to find out the relationship of reactive hyperglycemia with ischemic stroke prognostics at Budi Kemuliaan hospital in Batam city in 2020-2021. Method:Observasional analytic research with aproaching cross sectional that is done at RSBK in Batam City On December 2021. In this study, the population is all ischemic stroke patients recorded in medical records at Budi Kemuliaan Hospital Batam for the period August 2020 - July 2021.The technique of tacking sample is purpossive samply with the number of samples are 107. The result of resorser analysed with frequency distribution, tabulated crosswise then examined with chi-square. Result:The result of analysis chi-square is obtained p= 0,003 where p is smaller than with significancy level alfa = 5% (0,05). Conclusion:There is the relationship between reavtive hyperglycemia with prognostik of ischemic stroke at RSBK Batam city.
Econometric Modeling of the Markets Boundaries
Authors:   Eurasian Economic Commission, Shakkaliyev Arman A.
Published: October 2022

The relevance of the study is due to the special importance of correctly determining the product boundaries of the cross-border markets of the Eurasian Economic Union (EAEU) in the process of antimonopoly regulation. An erroneous definition of such parameters leads to an incorrect definition of the product, and, as a result, to a narrowing or expansion of the scope and geography of its circulation, an increase or blurring of the shares of entities operating in the markets, a false level of concentration, as well as a distortion of the criteria for delineating the competence of the EEC and national authorities in terms of abuse of dominance. This process can be much more complicated when it comes to goods that are subject to technical regulations, and due to their specificity, there are a significant number of types of goods that are generally similar in some respects, but differ in others. In this regard, within the framework of the study, an attempt was made to assess the possibilities of using certain methods of econometric modeling when establishing product boundaries for cross-border markets for such goods using the example of non-electric initiation systems. The research hypothesis is based on the following assumptions. First: technical regulations and standards not only act as market entry barriers, but also have a decisive influence on the definition of a market within which goods equivalent to each other circulate. Second: when determining the product boundaries of markets operating in the system of technical regulation, along with traditional and normatively fixed approaches, multiple regression models can be used and a correlation between the cost of a product and its characteristics, as well as empirical analysis data that allows segmenting goods according to specific boundaries, can be used.
DOWNHOLE THERMOELECTRIC MODULE SYSTEM TO EXPAND THE APPLICATION AND INCREASE THE EFFICIENCY OF THE STEAM GRAVITATION INFLUENCE METHOD
Authors:   SATBAYEV UNIVERSITY, Republic of Kazakhstan, 050013, Almaty, st. Satpaeva, 22, ZAURBEKOV K.S. , SYZDYKOV A.KH. ,   SATBAYEV UNIVERSITY, Republic of Kazakhstan, 050013, Almaty, st. Satpaeva, 22, ZAURBEKOV S.A. ,   SATBAYEV UNIVERSITY, Republic of Kazakhstan, 050013, Almaty, st. Satpaeva, 22
Published: October 2022

The article discusses the existing technologies for thermal insulation of tubing (tubing) when using thermal methods of influencing an oil reservoir with high-viscosity oil, inherent in the fields of Kazakhstan. An urgent problem in the use of steam cycle treatment (CSS), steam gravity treatment (SAGD) and in situ combustion is significant heat loss with increasing well depth, which imposes restrictions on the use of these enhanced oil recovery methods. The large depth of occurrence of productive formations with high viscosity of fluids causes this problem of delivering the coolant to the productive formation with a given steam temperature, since the main indicator of the effectiveness of the use of thermal methods is the temperature of the coolant, in connection with which the solution of the issue of reducing heat losses in the process of delivering the coolant through the tubing string to a productive reservoir is an important technical problem, the solution of which with minimal costs of material resources will increase the interest of mining companies in the application of these methods, namely the SAGD technology. The paper carried out a comparative analysis and recommended a technology that improves the efficiency of the SAGD method for the fields of Kazakhstan. Currently, there are two main technologies for thermal insulation of the tubing string using the SAGD method, in high-viscosity oil fields - vacuum insulated tubing (Vacuum Insulated Tubing-VIT); - heat-insulated tubing. This article proposes a new method based on the conversion of electricity into heat by placing a borehole thermoelectric module in the tubing string. The proposed downhole thermoelectric module system makes it possible to maintain the coolant temperature along the entire length of the wellbore, which makes it possible to apply the SAGD method to depths of 1500 meters or more. The design of the downhole thermoelectric module system is simple, technologically advanced, reliable in operation and easily replicable. The downhole thermoelectric module system, placed in the tubing string, provides the possibility of increasing the depth of wells using the SAGD method and is characterized by a significantly lower cost compared to vacuum insulated tubing (VIT) and heatinsulated tubing systems. Modern heat cables of the SAMREG 40-2CR type, manufactured in South Korea, provide power up to 40 W / m, which is quite enough to maintain the desired temperature of the coolant. The cable is characterized as a self-regulating, heating, heating, shielded cable (braided), operates from a mains voltage of 220-240 V, with a frequency of 50 Hz.
FACTORS AFFECTING THE GAS RECOVERY COEFFICIENT AT GAS CONDENSATE FIELDS WITH ABNORMALLY HIGH RESERVOIR PRESSURE
Authors:   SATBAYEV UNIVERSITY, Republic of Kazakhstan, 050013, Almaty, 22-a Satpayev str., MOLDABAEVA G.J. , AGZAMOV A.Х. ,   TASHKENT STATE TECHNICAL UNIVERSITY NAMED AFTER ISLAM KARIMOV, 2-a, Universitetskaya Street, Tashkent,100095, Republic of Uzbekistan, ABBASOVA S.A. ,   TASHKENT STATE TECHNICAL UNIVERSITY NAMED AFTER ISLAM KARIMOV, 2-a, Universitetskaya Street, Tashkent,100095, Republic of Uzbekistan, SULEIMENOVA R.T. ,   SATBAYEV UNIVERSITY, Republic of Kazakhstan, 050013, Almaty, 22-a Satpayev str., MUKHAMMADIEV H.M. ,   KARSHINSKY INSTITUTE OF ENGINEERING AND ECONOMICS, 225 MUSTAKILLIK SQUARE, KARSHI, 180100, REPUBLIC OF UZBEKISTAN
Published: October 2022

The results of numerical experiments to assess the influence of abnormally high reservoir pressure on the dynamics of pressure reduction at the bottom and the supply circuit, flow rate and life of wells are presented. It is shown that the growth of the anomaly coefficient of reservoir pressure has a positive effect on the dynamics of the considered indicators. It has been established that in hydrocarbon deposits with abnormally high reservoir pressures, the rock pressure of up to 75% is balanced by the pressure of saturating hydrocarbons. High rates of gas extraction, achieved due to large depressions on the reservoir in producing wells, lead to reservoir deformation, which in fractured and fractured-pore reservoirs leads to the closure of hydrocarbon filtration channels. Using the example of the Severny Nishan gas condensate field, it is shown that the deformation of the reservoir is the main reason for the low efficiency of development and the abandonment of half of the gas reserves in the reservoir. Hydraulic fracturing technology is recommended for the extraction of residual gas reserves. With an increase in the depth of the productive horizons, the proportion of hydrocarbon deposits with abnormally high reservoir pressures is steadily increasing. As it is known, the energy potential of productive layers is largely determined by the activity of the legal aquifer area. There are elision and infiltration natural water pressure systems. The experience of developing hydrocarbon deposits with AVPD shows that this factor, depending on the geological and physical conditions of the deposits, can affect the oil and gas recovery coefficient as a positive (increasing) and negative (decreasing) factor. At the same time, as positive factors, there is a higher concentration of reserves in the specific volume of the deposit, relatively high well flow rates, ensuring the gushing of wells for a long time, maintaining high reservoir properties of reservoir rocks, and as a negative factor, a decrease in stability and susceptibility of oil and gas saturated reservoirs to deformation processes.
OBTAINING ELASTOMERIC CORONOELECTRETES FOR SEALING UNITS OF OILFIELD EQUIPMENT
Authors:   M. AUEZOV SOUTH KAZAKHSTAN UNIVERSITY, 5, Tauke Khan Avenue, Shymkent, 160012, Republic of Kazakhstan, KYDYRALIEV A.SH. , BEISENBAYEV O.K. ,   M. AUEZOV SOUTH KAZAKHSTAN UNIVERSITY, 5, Tauke Khan Avenue, Shymkent, 160012, Republic of Kazakhstan, NADIROV K.S. ,   M. AUEZOV SOUTH KAZAKHSTAN UNIVERSITY, 5, Tauke Khan Avenue, Shymkent, 160012, Republic of Kazakhstan, BIMBETOVA G.ZH. ,   M. AUEZOV SOUTH KAZAKHSTAN UNIVERSITY, 5, Tauke Khan Avenue, Shymkent, 160012, Republic of Kazakhstan
Published: October 2022

The article discusses the issues of obtaining elastomeric coronoelectretes for sealing units of oilfield equipment. In the conditions of collecting and preparing oil in the fields, the issues of using products based on rubber compounds for sealing during the operation of equipment in direct contact with the borehole fluid, which is to a certain extent an aggressive environment, are relevant. The composition of a polymer elastomeric coronoelectret for sealing units of oil industry equipment has been developed. The composite is based on low-density polyethylene, butadiene - nitrile synthetic rubber of the BNKS-18AMN brand, ethylene copolymer with vinyl acetate (savylene 11104-030), technical gossypol, organic modifiers. The effect of additives on the electret properties of composites is shown. Based on experimental data, it was found that the resulting composite material based on modified low-density polyethylene, savylene, technical gossypol, organomodified layered silicates, butadiene-nitrile rubber in the electret state has sufficient resistance, and giving them an electret state additionally reduces the amount of their swelling in the conditions of production of borehole products.
CURRENT STATE AND DEVELOPMENT OF OIL PIPELINE TRANSPORT OF OIL AND GAS OF THE REPUBLIC OF KAZAKHSTAN
Authors:   INSTITUTE OF ECONOMICS OF THE SCIENCE COMMITTEE OF MINISTRY OF EDUCATION AND SCIENCE (MON) OF THE REPUBLIC OF KAZAKHSTAN 29,Kurmangaxy st., Almaty city, 050000, Republic of Kazakhstan, OSMANOV Z.D.
Published: October 2022

Based on the analysis of the current state, it was revealed that Kazakhstan has significant reserves of fuel and energy resources: proven oil reserves exceed 4 billion tons. Due to the fact that Kazakhstan's own consumption of energy resources is less than their production, the remaining amount is sold on world markets. This article describes that the most preferred mode of transport of energy resources are pipelines, which have the following indisputable advantages: they can be laid in any direction and at any distance, regardless of the landscape; their operation practically does not depend on external conditions (weather conditions, time of year and day); they are more reliable than other types of energy transport and are automated to the greatest extent; cargo delivery is carried out almost all year round, without idle mileage, characteristic of tanks and ships when using other types of transport. In addition, it was recommended that the use of pipelines makes it possible to free up rail and water transport for the transportation of other goods. It was also proposed to expand the routes of transport systems connecting the Caspian oil and gas region with the regions of southern, central and eastern Kazakhstan, which will improve their security in the consumption of hydrocarbon resources. Partial or complete rejection of natural gas imports due to its supplies from the fields of Western Kazakhstan will ensure not only a reduction in foreign exchange costs for its purchase from Uzbekistan, but also reduce dependence on fluctuations in its prices due to changing market conditions and seasonality of supplies. This circumstance justifies the need to redistribute gas resources in the direction of solving the issues of providing the southern region of Kazakhstan with sufficient volumes of this type of resources.
Alzheimer's disease - neurological or psychiatric disorder?
Authors:   Department of Neurology, Floreasca Emergency Hospital Bucharest, Romania, Poalelungi Alina , Popescu Bogdan O. ,   Department of Neurology, Colentina Clinical Hospital – CDPC, School of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Laboratory of Molecular Medicine, “Victor Babes” National Institute of Pathology, Bucharest, Romania
Published: October 2022

Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is the most common form of dementia in the elderly. The clinical manifestations of Alzheimer’s disease evolve from an initial discrete impairment of recent memory to severe cognitive loss, in time behavioural and psychiatric symptoms becoming obvious and disturbing. The cause of this complex clinical picture is the gradual functional deterioration and eventually loss of all brain cell types, with severe alteration of neuronal networks supporting cognitive processes. The aim of this paper is to examine different features of AD and to formally establish whether it belongs to the neurological or psychiatric group of disorders. A review of key literature in the field was performed for main attributes of AD neuropathology and pathophysiology. In this respect, we have compared AD with classical psychiatric disorders (schizophrenia, bipolar disorder, obsessive compulsive disorder) and with neurological degenerative disorders (AD, Parkinson’s disease, epilepsy, amyotrophic lateral sclerosis, Huntington’s disease). In brief, AD pathogenic mechanisms involve protein aggregation, synapse alteration, oxidative stress, neurotransmitter deficit, intracellular calcium dyshomeostasis and mitochondrial dysfunction, all together finally leading to cell death and brain atrophy. To some extent, some of these features are common for both psychiatric and neurodegenerative disorders. However, from the cellular and molecular pathology perspective, AD seems to be closer to other neurological conditions than to classical psychiatric diseases.
Early onset of ocular autoimmune myasthenia - case report
Authors:   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Teleanu Raluca Ioana ,   “Dr. Victor Gomoiu” Children’s Hospital, Department of Pediatric Neurology, Bucharest, Romania, Nita , Smaranda ,   “Dr. Victor Gomoiu” Children’s Hospital, Department of Pediatric Neurology, Bucharest, Romania, Vasile Daniela ,   “Dr. Victor Gomoiu” Children’s Hospital, Department of Pediatric Neurology, Bucharest, Romania
Published: October 2022

The article aims to present a rare case of autoimmune myasthenia diagnosed in our clinic with an onset before the age of a girl initially presenting blepharoptosis, exotropia and nystagmus. The exclusive ocular involvement has persisted throughout the clinical course of eleven months until the present moment, showing partial improvement under daily administration of pyridostigmine bromide. Finally we wish to underline the future possible outcomes and management options which were taken into consideration in this case, as well as to emphasize the positive role of a multidisciplinary approach in assessing pediatric patients.
Incidence and hospitalization rate of syncope in a non-emergency hospital
Authors:   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Buzea Catalin A. ,   Colentina Clinical University Hospital, Bucharest, Romania, Dan Anca R. ,   Colentina Clinical University Hospital, Bucharest, Romania, Dan Gheorghe A. ,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Colentina Clinical University Hospital, Bucharest, Romania
Published: October 2022

Syncope is a frequent medical condition presented to Emergency Rooms and an important source for hospitalization. Little is known in our country about characteristics of patients with syncope presented as an emergency or not. Our aim is to evaluate epidemiologic features of all patients considered to have syncope and assessed in ambulatory or in-hospital setting in a teaching non-emergency hospital. We included 164 patients with diagnosis of syncope evaluated in neurology or cardiology departments over a one year period. We found that these patients represent 1.1% of total patients admitted in both departments, 62.2% being hospitalized, mostly in neurology department. The patients considered for in-hospital assessment were older and with more comorbidities than those evaluated in ambulatory setting. The most frequent cause of syncope was reflex and we found a significantly high incidence of diagnosis of unexplained syncope. We concluded that syncope represents a major symptom for clinicians and often the cause remains hidden because of heterogenous approach to these patients. This emphasize the multidisciplinary aspect of patients with syncope and the necessity of implementation of standardized pathways for their evaluation.
The influence of neurotrophic factors treatment on stroke volume
Authors:   Neurology Department, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, Romania, Stan Adina Dora , Badisor Alexandru ,   Neurology Department, Emergency County Hospital Cluj-Napoca, Romania, Birle Codruta ,   Neurology Department, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, Romania, Blesneag Alina Vasilica ,   Neurology Department, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, Romania, Opincariu Iulian ,   Radiology Department, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, Romania, Iancu Mihaela ,   Department of Medical Informatics and Biostatics, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, Romania, Racasan Dana ,   Neurology Department, Emergency County Hospital Cluj-Napoca, Romania, Muresanu Dafin Fior ,   Neurology Department, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, Romania
Published: October 2022

Background. Cerebrolysin is a multimodal drug, with pleiotropic neuroprotective effects that simultaneously promotes neuroprotection while retaining the ability to influence neuroplasticity. Cerebrolysin is approved for the treatment of stroke, traumatic brain injury and cognitive dysfunction. Methods. A randomized, double-blind, placebo-controlled clinical trial was conducted in sixty patients with acute supratentorial ischemic stroke. The patients were randomized to either Cerebrolysin 30 ml/day (n = 30) or placebo (n = 30) in a 1:1 manner. The treatment period was 10 days. Stroke volume was measured in the first 24 hours after stroke onset using diffusion-weighted images, and it was measured again at 30 days after stroke using fluid attenuated inversion recovery images. Results. A significant reduction of stroke volume at 30 days was demonstrated in both Cerebrolysin- and placebo treated patients (p < 0.001). Although it was not statistically significant a better response in stroke volume reduction was observed in the Cerebrolysin-treated group, compared to the placebo group (Mann Whitney test, U = 426, p = 0.723, mean rank, 29.70 vs. 31,30). Interpretation. We demonstrated a positive effect from Cerebrolysin treatment to reduce ischemic stroke volume.
Secondary prevention in patients with atrial fibrillation and stroke or transient ischemic attack - an insight from the FACTS programme
Authors:   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Popescu Raluca , Dan Gheorghe A. ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Colentina Clinical Hospital, Bucharest, Romania, Buzea Adrian ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Colentina Clinical Hospital, Bucharest, Romania
Published: October 2022

Background. Cardioembolic stroke secondary to atrial fibrillation (AF) accounts for 1.5%-23.5% of all ischemic strokes. Patients with prior stroke or transient ischemic attack (TIA) are at high risk for stroke recurrence. Prognosis for patients with AF related stroke is worse than those with other types of stroke. According to the current guidelines secondary prevention in these patients should be based on anticoagulant therapy. Aim of the study. The purpose of this analysis is to evaluate the extent of anticoagulation in clinical practice in patients with previous stroke or TIA. Methods. We have evaluated records obtained from the FACTS registry. We included 374 patients with AF and a history of stroke or TIA, from different areas of Romania, and collected data regarding antithrombotic therapy. Results. According to CHADS2 all patients were at high risk and should receive anticoagulation therapy. In our group 51,37% were treated with OAC alone and 15,77% with OAC in combination with antiplatelet therapy. Of OAC the most used drug was acenocoumarol and optimal anticoagulation (INR between 2 and 3) was found in 68% patients. There were no differences between genders and OAC prescription was not influenced by AF type. OAC was preferred in 68.52% patients with high bleeding score (HASBLED > 3). Conclusion. The main finding of the analysis was that adherence to guidelines recommendation concerning AF patients with previous stroke/TIA is still low. However, patients at high risk for stroke recurrence and high bleeding score were mostly treated according to current recommendations, suggesting that there is an increasing awareness and adherence to current clinical guidelines.
Electromagnetic shielding characteristics of carbon and glass fiber composites
Authors: ÇOŞKUN Yücel , TABAKCIOĞLU Mehmet
Published: October 2022

Electromagnetic shielding characteristics for orientation angle and number of plies of carbon fiber reinforced epoxy composites were investigated in the frequency range between 900 and 6000 MHz. In this study, both unidirectional and bidirectional carbon fiber fabrics were utilized as reinforcement materials to manufacture the composite samples. Twill bidirectional glass fiber fabrics were also used in order to provide a large amount of flexibility. To prepare the composite laminates for measurement, hand lay-up method was preferred. Measurements were carried out by using DFG 4060 signal generator and HF 60105 spectrum analyzer. According to the measurements, it was observed that electromagnetic shielding effectiveness (EMSE) was very higher when the orientation angle of the carbon fiber was 90°, as compared to 0°. Another parameter that affects EMSE is whether the carbon fiber fabric used is unidirectional or bidirectional because it was observed that the bidirectional fabric increased EMSE. In addition, it has been determined that the number of plies has less effect on EMSE than the orientation angle.
Intravenous contrast induced acute kidney injury prevention with high doses of statins
Authors: Vasin A. A. , Mironova O. Iu. , Fomin V. V.
Published: October 2022

Aim. The aim of our study was to assess the frequency of contrast-induced acute kidney injury (CI-AKI) in patients undergoing computed tomography (CT) with intravenous contrast media and to evaluate the effects of statins in the prevention of CI-AKI.   Materials and methods. 181 patients undergoing CT with intravenous contrast media administration were included in prospective observational study (ClinicalTrials.gov ID NCT04666389). The primary endpoint was CI-AKI according to KDIGO criteria (the 25 % rise (or 0,5 mg/dl) of serum creatinine from baseline assessed 48–72 hours after administration of contrast media). There were 120 patients in the group with high dose of statins administration and 60 patients without statin treatment. The most frequent cardiovascular disease was hypertension in both groups — 93 % and 85 % respectively.   Results. CI-AKI was diagnosed in 12 (6,7 %) patients — 9 patients in the no statins group and 3 patients in the statins group. The high dose statin administration statistically significant had less frequency of CI-AKI (p = 0,003) compare with no statins group (OR = 0,144, 95 %CI: 0,037–0,554).   Conclusion. Statin pretreatment is effective at preventing CI-AKI and should be considered in high-risk patients.
Features of the manifestation of arterial hypertension in patients with a new coronavirus infection
Authors: Solnceva T. D. , Lachugin A. A. , Sivakova O. A. , Chazova I. E.
Published: October 2022

The purpose. Assessment of the presence of the cardiovascular risk factors, associated clinical conditions, the degree of target organ damage in patients with arterial hypertension depending on the new coronavirus infection.   Material and methods. In a retrospective cohort study 284 patients with arterial hypertension were identified, 162 of them had a novel coronavirus infection and 122 patients didn’t have a history of a new coronavirus infection. Patients who had a new coronavirus infection were divided into groups depending on the disease. Inclusion criteria were the presence of arterial hypertension in history and taking antihypertensive therapy.   Results. Patients with hypertension who’ve had a new coronavirus infection are more likely to have risk factors such as smoking, overweight, early menopause as opposed to patients with hypertension without indication of past COVID-19. Comparing patients with increased severity of the novel coronavirus infection elevated uric acid levels and hypercholesterolemia were associated with more severe COVID-19 (p < 0.05). Patients with chronic kidney disease, cerebrovascular disease, detection of atherosclerotic lesions of the brachiocephalic arteries and diabetes mellitus have an increased probability of deaths occur from the novel coronavirus infection (p < 0.05). There was no significant difference between the compared groups of coronary heart disease, atrial fibrillation, chronic heart failure and also the daily blood pressure profile and a severe course of COVID-19.   Сonclusion. The presence of diabetes mellitus, cerebrovascular disease, chronic kidney disease, detection of atherosclerotic lesions of the brachiocephalic arteries, and also hyperuricemia or hypercholesterolemia in patients with hypertension revealed a risk of severe coronavirus infection.
A Study on the Revitalization of Start-up in Daegu Metropolitan City through the Analysis of Domestic and Foreign Start-up Trends
Authors:   National Association of Korean Local Government Studies, Kim SangHwa
Published: October 2022

This study analyzed and identified overseas and domestic start-up policies, and based on this, an analysis of the start-up status of Daegu City and a plan to revitalize start-ups were derived.
For the definition of start-up, technology start-up, domestic start-up support policy, Daegu city start-up support status, overseas start-up support policy, etc. were reviewed and comprehensively described.
First, it is necessary to create a sustainable virtuous cycle venture and start-up ecosystem in Daegu. Daegu presented a strategy for promotion based on the implications derived from start-up and technology startup support policies, venture business trends, venture/startup cluster analysis, and R&D and technology innovation capability analysis. The promotion strategy was divided into an integration strategy that performs tasks for each base and a linkage plan related to various parts.
It is necessary to establish a start-up total service base center that provides integrated services for start-up support, a venture/startup service town, and strengthen entrepreneurship and start-up literacy education. It is necessary to establish a virtuous cycle structure linked to each company through the vitalization of industry-university joint research and continuous expansion of the maintenance of start-ups through the Beisle Valley base center that supports innovative growth after start-up and intensively fosters start-ups in the manufacturing sector. Based on Shinseo Innovation City in Dong-gu, where the medical industry infrastructure, one of Daegu City’s key businesses, is concentrated, Medi City Daegu supports medical and pharmaceutical startups and medical-related businesses such as healthcare and medical tourism. A complex support system is needed, such as establishing a center, promoting the commercialization of medical technology, attracting large medical-related companies, and establishing a cooperative system.
A METHOD FOR THE STAKE-OUT OF THE SEATS IN THE CONFERENCE ROOM
Authors: Ata Ercenk , Hoşbaş Ramazan Gürsel , Pirti Atınç
Published: October 2022

Before the application, the coordinates of the circle shaped seat places that will be applied in indoor space can be obtained by the help of common points determined in numerical project model formed in a local coordinate system. Practically, the coordinates of the points in the digital project model can be also obtained numerically by using the coordinates of the common points. However, converting to numerals manually, the factors such as the support quality of the project, exhaustion of the operator, hand tremble and screen resolution influence the sensitivity of the conversion to numerals. Errors made during the conversion negatively affect the coordinates of the points. The most suitable method not to make errors is the calculation of coordinates of the points in the project model by geodetic method. In this project, the calculation of the coordinates of the seat midpoints placed on the curves in a closed area, benefited from the corner point coordinates of the seats in the indoor space obtained from geodetic measurement in a local coordinate system before the application and benefited from the data of the other points of the indoor space are explained. Furthermore, the ground application of the midpoints of the seats on each curve row is explained. The accuracy of the stake-out of seats in the conference room is obtained between 1 and 2 cm.
DETERMINATION OF MALL BUILDING VERTICAL DISPLACEMENTS BY SEDIMENTARY MARKS
Authors: Serant Oksana , Sidorov Ihor , Balyan Andrij , Kubrak Olena , Yarema Nataliya , Dzhuman Bohdan
Published: October 2022

The purpose of this paper is to determine the optimal method of researching the vertical displacements of buildings and stability of the marks, on the basis of which it is possible to make a conclusion about the subsidence of the researched building. Methodology. The main task of geodetic observations for buildings monitoring is to identify changes in the spatial position of load-bearing structures (vertical and horizontal displacements) to assess the risk of structures destruction, dismantling unstable structures, forecasting accidents. In this paper we offered to carry out monitoring by a method of high – precision geometrical leveling on the established geodetic marks, according to one scheme with constant points of devices installation. For testing this method 13 cycles of II class leveling were conducted to determine the vertical displacements of sedimentary marks of the “Shuvar” mall building. To detailed determination of the building deformation, namely its sediment on two floors, we laid 70 marks in the floor on the first floor and 41 marks on the second floor. Stainless steel anchors were used as marks. Findings. According to the results of observations of the laid sedimentary marks we determined their conditional heights. The difference of determined heights of the same marks for a certain period of time allows to determine the vertical displacements. The results of measurements were equilibrated by the nodal point method, and the leveling line was closed on each floor, so the equilibrations were performed separately for each floor. As a result we obtained the heights of sedimentary marks and the mean square errors of their determination. We constructed schedule of heights change of the chosen marks of the first floor within 13 cycles andcarried out the analysis of the reasons of these changes. Practical implications and originality. Observations of landslides, subsidences and deformations of the building have great importance for determining the strength and stability of the building to prevent its destruction or give signal in a timely manner of an emergency, which can become vital. In this paper method for monitoring the vertical displacements of buildings is proposed and tested. The obtained results suggest that proposed method of observations can be recommended to determine the vertical displacements of such buildings and complexes.
CALIBRATION OF THE LOW-COST UAV CAMERA ON A SPATIAL TEST FIELD
Authors: Sobura Szymon
Published: October 2022

For several years, the widening range of applications of unmanned aerial vehicles can be noticed not only in the literature review but also in the market of services offered – also in the geodetic sector. While there is a wide range of professional UAVs for aerial mapping tasks, these platforms are expensive. In this study, it was checked whether the calibration of a low-cost drone camera allows for obtaining an accuracy acceptable for photogrammetric studies. For this purpose, a spatial test field was designed on which a multivariate calibration of the UAV camera and control of the obtained results were carried out. Using the elements of the camera’s internal orientation obtained during the calibration process, it was not possible to achieve high accuracy of photogrammetric measurements on control images. This may indicate a problem with the repeatability of determining the elements of internal orientation of the analyzed camera, and thus with the instability of the autofocus system. Nevertheless, the use of the obtained results from the camera calibration as precise approximations of the elements of the camera’s internal orientation had a positive effect on the solution of the image network using the bundle adjustment and the fitting of the spatial model to the ground control points. In addition, the UAV flight over the created spatial test field allowed for a reliable assessment of the possibilities and accuracy that can be obtained on the basis of images from a low-cost drone.
Informing the Cataclysmic Variable Sequence from Gaia Data: The Orbital-period–Color–Absolute-magnitude Relationship
Authors: Abrahams Ellianna S. , Bloom Joshua S. , Szkody Paula , Rix Hans-Walter , Mowlavi Nami
Published: October 2022

The orbital-period (P
orb) gap in the population of cataclysmic variables (CVs) informs the theoretical narrative of CV evolution, yet a complete understanding of the driving angular momentum loss mechanisms above and below this gap remains elusive. Here we identify, for standard CVs, a new, apparently monotonic relationship between quiescent color (G
BP–G
RP), absolute magnitude (M

G
), and P
orb (between 70 minutes and 8 hr) revealed in Gaia DR2 and EDR3. We show that P
orb increases in the color–absolute-magnitude diagram roughly orthogonally to the white dwarf and main sequences. We find the orbital-period–color–absolute-magnitude relationship to be stable across different CV subtypes: dwarf novae, intermediate polars, polars, and novalike systems. We place our findings in context with the known semiempirical donor sequence for CVs and find a dependence between color and M

G
for a given P
orb specifically for dwarf novae and intermediate polars above the period gap. These relations have the potential to inform a more complete picture of CV evolution.