bluuebunny/crossref_metadata_2025 huggingface dataset:
La clave crítica bien temperada: Baquero Goyanes en su partitura
Authors: Cervera Salinas Vicente
Published: June 2023

his article traces an itinerary through the critical work of Mariano Baquero Goyanes from his recognized love of the art of music. Since his first investigations in the fifties, as in "Tiempo en tempo en la novela" (1954), the references to musical techniques and forms as well as to the history of music fertilize and illuminate his scientific contribution in an original and pioneering way. to literary criticism. The pages devoted to musical structures in contemporary novels, already in the seventies, reveal his critical maturity and the breadth of the field of vision of the artistic phenomenon.

Este artículo traza un itinerario por la obra crítica de Mariano Baquero Goyanes desde su reconocida afición al arte de la música. Desde sus primeras investigaciones en los años cincuenta, como en "Tiempo en tempo en la novela" (1954), las referencias a las técnicas y formas musicales así como a la historia de la música fecundan e iluminan de modo original y precursora su aportación científica a la crítica literaria. Las páginas dedicadas a las estructuras musicales en la novelística contemporánea, ya en los años setenta, revelan su madurez crítica y la amplitud del campo de visión del fenómeno artístico.
Determination of Nuclear DNA Content and Chromosome Number of Verbascum scamandri Murb. (Scrophulariaceae)
Authors: YÜCEL Gülru , CAMBAZ Ebru , ÇÖRDÜK Nurşen
Published: June 2023

The aim of the study was to determine the chromosome number and nuclear DNA content of an endemic plant, V. scamandri, using 14-week-old plants germinated from seed and to determine the genetic stability based on flow cytometry analyses in callus tissue induced MS medium containing 1 mg/L Kin + 1 mg/L 2,4-D and 9-week-old propagated plants, induced and developed on MS medium containing 2 mg/L Kin + 0.1 mg/L 2,4-D. In the mitotic chromosome counts showed V. scamandri had 2n = 16. Flow cytometric analysis revealed that 14-week-old in vitro grown plants has 0.73 pg/2C ± 0.01, callus tissue has 0.76 pg/2C ± 0.02 and propagated plantlets has as 0.79 pg/2C ± 0.01. The results proved that propagated plants had similar DNA content to the seed-derived plants which showed analysed plants were genetically stable.
Éléments de validité à propos d’un instrument mesurant le climat relationnel perçu par des étudiants et étudiantes universitaires à distance1
Authors: Baillifard Ambroise
Published: June 2023

Le questionnaire Climat relationnel des études à l’Université (CREU) (Genoud, 2008) a été adapté en français et en allemand et intitulé Climat relationnel des études à distance (CRED). Une analyse factorielle confirmatoire (n = 223) soutient la structure du CRED en quatre sous-échelles. D’autres éléments de validité sont fournis par des coefficients de cohérence interne et par la comparaison avec les résultats antérieurs obtenus par Genoud (2008). Toutefois, une faible invariance de mesure entre les échantillons (francophones et germanophones) et des indices d’ajustement parfois insuffisants, en particulier pour la version allemande, invitent à la nuance. La validité de critère est étayée par des liens significatifs positifs entre le sentiment d’auto-efficacité, la persévérance et la qualité perçue du climat relationnel (CRED). Des liens négatifs ont été trouvés entre le CRED et la propension à l’ennui (SBPS). Aucun lien n’apparait entre le climat relationnel et les performances (notes).
Kindergarten teachers’ knowledge of and beliefs in the influence of music and movement on children’s self-regulation
Authors: NG Siu-Ping , Bautista Alfredo , Williams Kate E.
Published: June 2023

Un número creciente de estudios indica que la exposición temprana a la música y el movimiento (M&M) impacta positivamente en la autorregulación infantil. Sin embargo, se ha prestado poca atención a lo que las y los docentes de infantil saben y creen sobre la relación entre M&M y la autorregulación, y menos aún a cómo sus propias experiencias de M&M se relacionan con sus conocimientos y creencias. El presente estudio investiga dichos temas utilizando datos de encuestas de 306 maestros de infantil de Hong Kong. Se realizaron análisis descriptivos, de correlación y pruebas t de muestras independientes. La mayoría de participantes creían poseer un alto nivel de comprensión sobre el tema, en particular aquellas con experiencia en M&M. Dichas participantes tenían creencias más sólidas de que M&M fomenta la autorregulación infantil, específicamente las habilidades de coordinación motora, el control de impulsos y el manejo emocional. Concluimos que el conocimiento y las creencias de las y los docentes de infantil sobre el papel de la M&M para apoyar la autorregulación están influenciados por sus propias experiencias de M&M. A mayor experiencia, más profundo será su entendimiento sobre cómo la M&M contribuye a las habilidades de autorregulación infantil. La principal implicación es la necesidad de exponer aún más a las y los docentes de Infantil a las experiencias de aprendizaje de M&M, ya sea de manera formal o informal.
Overview of Criteria and Scenarios Relevant for Development of Seaports of County and Local Importance in the Republic of Croatia
Authors: Jugović Alen , Jardas Antonić Jelena , Aksentijević Dea
Published: June 2023

The development of seaports is a complex process influenced by a number of external factors, from the economic ones to the social environment. Seaports differ from each other in their spatial and functional characteristics, the complexity and purpose of their operation, as well as the need for investment and additional construction of port infrastructure and superstructure, so their development must be approached analytically. In order for the proposed development guidelines to be applicable to ports with similar characteristics, it is necessary to define criteria for their classification. Relevant criteria for classifying and planning the development of seaports are derived from: laws and regulations established by legal regulations, goals and plans proposed by current strategic documents, and spatial plans that set the conditions for planning, forming and developing ports in a certain area. The purpose of this scientific work is to determine which national and regional regulations and documents affect the development of regional ports in the Republic of Croatia, and to define classification criteria that will serve as a basis for the formation of development directions for seaports.
Libidinal attitudes in women (self pleasure and self punishment) yield to a glamorous and more elastic skin
Authors: Martini Lorenzo
Published: June 2023

Nowaday a new fashion exploded in US and other European countries: self pleasure in women (young or less young) guarantees a visco-elastic property to skin, and glamour and glow to the external appearance. This costume is spread through the brilliant world of actresses and movie stars, but more and more girls are trying to appropriate this attitude in order to attempt to remain always young and fashionable. The A recruited two women (the former elder and the latter younger) and prayed them to watch at porn magazins for two hours in one day and have self-plasure laying down on a couch calmly and serenely, and had the way to measure the visco-elasticity before and after the “amusement” by a Cutometer.
The Role of Energy Management in Achieving Climate Neutrality in Municipalities in Europe
Authors:   , Jēkabsone Anda
Published: June 2023

The EU has prioritized mitigating climate change, aiming to limit global warming to below 1.5 °C or 2 °C compared to pre-industrial levels. However, the latest IPCC report suggests that the existing policies are insufficient to meet this goal. Sustainable planning in municipalities is crucial for reducing risks and achieving global goals but it must be fair and avoid energy poverty. The objective of the Doctoral Thesis is to develop a methodology and recommendations for the implementation of systematic approach in municipal energy and climate management in order to ensure clear progress towards achieving climate neutrality goals, highlighting the role of energy management system in initiating specific actions.
MACROECONOMIC DETERMINANTS OF COMPETITIVENESS: EVIDENCES FROM FACTOR EFFICIENCY AND INNOVATION-DRIVEN COUNTRIES
Authors: Mohammadi Khyareh Mohsen , Rostami Nasrin
Published: June 2023

The investigation of factors that increase or hinder competitiveness has been one of the core tenets of theoretical and empirical researchers, but so far there has been no consensus. This study responds to this issue by exploring how different facets of the macroeconomic environment influence competitiveness in the three Global Entrepreneurship Monitor (GEM) types of economy (factor-driven economy, efficiency-driven economy, innovation-driven economy). Using Porter’s classification, we divided countries based on factor, efficiency and innovation. Additionally, the generalized method of moments (GMM) was used to capture endogeneity and unobserved heterogeneity of data in an unbalanced panel data for 81 countries (2002-2018). The results show that the variations of competitiveness across countries are mainly determined by variations in the stage of economic development. Firstly, GDP growth, low start-up costs and higher R&D expenditure play a key role in explaining the variation in competitiveness in three country clusters. Secondly, as regards Stage 1 countries, we find that trade openness, tax rate, GDP growth, start-up costs, real effective exchange rate, R&D expenditures and labor productivity are particularly vital for competitiveness. Concerning Stage 2 countries, we may observe that trade openness, tax rate, GDP growth, inflation, start-up costs, financial development, real effective exchange rate, R&D expenditures and labor productivity had a statistically significant impact on competitiveness. When it comes to Stage 3 countries, factors such as trade openness, FDI, tax rate, GDP growth rate, inflation, tax rate, startup costs, financial development, R&D expenditures, and labor productivity have an impact on competitiveness. This article presents some essential features, such as the macroeconomic index to determine competitiveness. These features can be used as guidelines for decision makers because they identify areas where taking further actions can improve competitiveness. Finally, our obtained results are highly consistent across a series of robustness tests and robustness checks covering alternative samples and alternative variable groups.
TOURISM POLICY DEVELOPMENT AND IMPLEMENTATION IN THE EASTERN CAPE PROVINCE, SOUTH AFRICA: DOES LOCAL STAKEHOLDER INVOLVEMENT COUNT?
Authors: Silwana Monwabisi , Nokubonga Dube Cynthia
Published: June 2023

Municipalities are at the lowest level of Government, and it is where the actual implementation of tourism policies takes place. District municipalities and communities globally often face poorly planned development projects resulting from inefficient and ineffective policy and planning implementation. One of the reasons for this is that there is, at times, a lack of participation by key stakeholders. The success of tourism development policies and their implementation rests on the involvement of all relevant stakeholders. This study adopted a qualitative research approach whereby purposive and snowball sampling methods were used to identify the research sample from the research population. The research population included the district municipality staff, regional and local tourism organisations, also known as tourism forums, tourism development agencies, and the rural planning and economic development departments. Consequently, fourteen (14) semi-structured interviews were conducted with key stakeholders from the district municipality, local municipalities, tourism organisations and Eastern Cape Parks Tourism Agency. A thematic analysis technique was used to analyse the data. This study focused on stakeholder involvement in the development and implementation of tourism policies in the O.R Tambo District Municipality (ORTDM). The key findings from the study revealed that there is a lack of stakeholder collaboration in development and the implementation of tourism-related policies in ORTDM.
ПРЕКИД ИЗВРШНОГ ПОСТУПКА
Authors: Рачић Ранка
Published: June 2023

До прекида извршног поступка долази мимо воље странака у извршном поступку. Прекид поступка доводи до обустављања извршне дјелетности. Субјекти извршног поступка, по правилу, не могу предузимати никакве радње у поступку за вријеме прекида. Прекид поступка доводи до одуговлачења извршне дјелатности и његово настављање у одређеним случајевима је упитно. Да би се разријешила ова кризна ситуација, законодавац је креирао правила о привременом заступнику кога странке могу поставити, у тачно одређеним случајевима, након доношења рјешења о прекиду поступка. Постављање привременог заступника има за циљ наставак и окончање започетог извршног поступка. У раду се анализира прекид извршног поступка који је само фрагментарно уређен у Закону о извршном поступку. Непотпуна регулатива у погледу овог процесног института има за посљедицу различито поступање судова. Неуједначена судска пракса у извршном поступку посебно је уочљива код постављања привременог заступника насљедницима странке која је умрла након покретања извршног поступка. Рад се бави анализом прекида извршног поступку са посебним освртом на привременог заступника и питање да ли он може да настави са заступањем, након доношења рјешења о насљеђивању, или странка у чије је име он постављен мора да преузме поступак. У судској пракси није непознат став да странка која је стекла својство тражиоца извршења или извршеника мора да „преузме“ поступак јер то превиђају правила којим је регулисана сукцесија у извршном поступку, уколико жели да се поступак настави.
НАКНАДА НЕМАТЕРИЈАЛНЕ ШТЕТЕ У ОБЛИКУ РЕНТЕ И ОСИГУРАНА СВОТА
Authors: Пејаковић Далибор
Published: June 2023

Овим радом покушава се анализирати институт накнаде штете у облику ренте. Након краћег приказа историјског развоја института нематеријалне штете и института накнаде штете у облику ренте, даје се анализа поступка и начина исплате доживотне ренте. Нарочито се ставља нагласак на поједине одредбе које прате институт накнаде штете у облику ренте, а посебно на проблеме који се јављају у пракси за случају да осигуравајуће друшто исплати цјелокупну осигурану своту. Скреће се пажња на предности и недостатке који се јављају код оваквог института, затим се даје кратак осврт на правне посљедице које прате институт доживотне ренте. Кроз приказ судске праксе и заузетог става суда у погледу основаности овог института у раду се аланизира значај исплате доживотне ренте, нарочито за случај када се ради о лицима која су тешко тјелесно повријеђена и истима је неопходна стална њега и помоћ. Резултат који се овим радом жели постићи јесте да се учини један допринос потпунијем и цјеловитијем сагледавању правних питања која се могу поставити у вези са институтом доживотне ренте.
DİJİTAL DEMOKRASİNİN DEĞERLENDİRİLMESİ: DEMOKRASİNİN SORUNLARINA BİR ÇARE Mİ YOKSA BİR MİT Mİ?
Authors: YEL Nurhan
Published: June 2023

DİJİTAL DEMOKRASİNİN DEĞERLENDİRİLMESİ: DEMOKRASİNİN SORUNLARINA BİR ÇARE Mİ YOKSA BİR
MİT Mİ?
Nurhan YEL
İstanbul Kültür Üniversitesi, Türkiye
n.yel@iku.edu.tr
https://orcid.org/0000-0002-5003-9996

ÖZ
İnternet tabanlı bilgi ve iletişim teknolojilerinin (BİT) gün geçtikçe artan kullanımı diğer tüm alanlarda olduğu gibi siyaset alanında da yeni beklentilerin ve anlayışların gelişmesine yol açmaktadır. Demokratik amaçlarla bu teknolojilerin kullanımına ilişkin beklentiler dijital demokrasi adı altında gelişen bir anlayışı beraberinde getirirken, beklenti düzeylerindeki farklılıklar, dijital demokrasi araç ve uygulamalarının tasarımlarına yansımaktadır. Temelde yönetsel süreçlere etkin vatandaş katılımını güçlendirmesi beklenen dijital demokrasinin, e-devlet, e-belediye gibi kamu yönetimleri tarafından hayata geçirilen örnekleri bulunmaktadır. Aynı zamanda, sivil toplum örgütleri ya da vatandaş inisiyatifleri tarafından aşağıdan yukarıya demokrasiyi hedefleyen uygulamaları geliştirilmektedir. Diğer yandan dijital demokrasinin gerek modern demokrasinin sorunlarını çözmede gerekse demokrasileri daha ileri bir noktaya taşıma konusunda ne denli etkili olacağına dair şüpheler de mevcuttur. Bunlardan bazıları dijital demokrasiyi bir mit olarak görmektedir ve kaygılarını dijital demokrasinin beklenenin tersine bir etki yaparak, demokrasinin altını boşaltacağı noktasına kadar taşımaktadır. Bu çalışmada dijital demokrasinin potansiyelinin ortaya konması ve değerlendirilmesi açısından önem taşıyan dijital demokrasiye yönelik yaklaşımlar ve beklentiler ile onların şekillendirdiği dijital demokrasi tanımları ve uygulamaları ele alınmıştır. Aynı amaç doğrultusunda, dijital demokrasinin önündeki engellerin anlaşılması için ona yöneltilen kaygı ve şüpheler de ele alınmaktadır.

Anahtar Kelimeler: Dijital demokrasi, e-demokrasi, e-devlet, e-belediye, dijital sermaye, dijital bölünme, dijital sermaye
Haploinsufficiency of the essential gene Rps12 causes defects in erythropoiesis and hematopoietic stem cell maintenance
Authors: Folgado-Marco Virginia , Ames Kristina , Chuen Jacky , Gritsman Kira , Baker Nicholas E
Published: June 2023

Ribosomal protein (Rp) gene haploinsufficiency can result in Diamond-Blackfan Anemia (DBA), characterized by defective erythropoiesis and skeletal defects. Some mouse Rp mutations recapitulate DBA phenotypes, although others lack erythropoietic or skeletal defects. We generated a conditional knockout mouse to partially delete Rps12. Homozygous Rps12 deletion resulted in embryonic lethality. Mice inheriting the Rps12KO/+ genotype had growth and morphological defects, pancytopenia, and impaired erythropoiesis. A striking reduction in hematopoietic stem cells (HSCs) and progenitors in the bone marrow (BM) was associated with decreased ability to repopulate the blood system after competitive and non-competitive BM transplantation. Rps12KO/+ lost HSC quiescence, experienced ERK and MTOR activation, and increased global translation in HSC and progenitors. Post-natal heterozygous deletion of Rps12 in hematopoietic cells using Tal1-Cre-ERT also resulted in pancytopenia with decreased HSC numbers. However, post-natal Cre-ERT induction led to reduced translation in HSCs and progenitors, suggesting that this is the most direct consequence of Rps12 haploinsufficiency in hematopoietic cells. Thus, RpS12 has a strong requirement in HSC function, in addition to erythropoiesis.
Self-formation of concentric zones of telencephalic and ocular tissues and directional retinal ganglion cell axons
Authors: Liu Wei , Shrestha Rupendra , Lowe Albert , Zhang Xusheng , Spaeth Ludovic
Published: June 2023

The telencephalon and eye in mammals are originated from adjacent fields at the anterior neural plate. Morphogenesis of these fields generates telencephalon, optic-stalk, optic-disc, and neuroretina along an axis. How these telencephalic and ocular tissues are specified coordinately to ensure directional retinal ganglion cell (RGC) axon growth is unclear. Here, we report the self-formation of human telencephalon-eye organoids comprising concentric zones of telencephalic, optic-stalk, optic-disc, and neuroretinal tissues along the center-periphery axis. Initially-differentiated RGCs grew axons towards and then along a path defined by adjacent PAX2+ optic-disc cells. Single-cell RNA sequencing identified expression signatures of two PAX2+ cell populations that mimic optic-disc and optic-stalk, respectively, mechanisms of early RGC differentiation and axon growth, and RGC-specific cell-surface protein CNTN2, leading to one-step purification of electrophysiologically-excitable RGCs. Our findings provide insight into the coordinated specification of early telencephalic and ocular tissues in humans and establish resources for studying RGC-related diseases such as glaucoma.
Development of rapid and cost-effective multiplex PCR assays to differentiate catfish of the genus Brachyplatystoma (Pimelodidae–Siluriformes) sold in Brazil
Authors: Freitas Leilane , Barbosa Andressa J. , Vale Bianca A. , Sampaio Iracilda , Santos Simoni
Published: June 2023

The catfishes Brachyplatystoma filamentosum (Kumakuma), Brachyplatystoma vaillantii (Laulao catfish), and Brachyplatystoma rousseauxii (gilded catfish) are important fishery resources in Brazil, where they are sold both fresh and in the form of fillets or steaks. These species have morphological similarities, thus, they can be easily misidentified or substituted, especially after processed. Therefore, accurate, sensitive, and reliable methods are needed for the identification of these species to avoid commercial fraud. In the present study, we develop two multiplex PCR assays for the identification of the three catfish species. Each multiplex protocol combined three species-specific forward primers and a universal reverse primer to produce banding patterns able to discriminate the target species unequivocally. The length of the cytochrome C oxidase subunit I (COI) fragments was approximately 254 bp for B. rousseauxii, 405 bp for B. vaillantii, and 466 bp for B. filamentosum, while the control region (CR) assay produced fragments of approximately 290 bp for B. filamentosum, 451 bp for B. vaillantii, and 580 bp for B. rousseauxii. The protocols were sensitive enough to detect the target species at a DNA concentration of 1 ng/µL, with the exception of the CR of B. vaillantii, in which the fragment was only detectable at 10 ng/µL. Therefore, the multiplex assays developed in the present study were sensitive, accurate, efficient, rapid, and cost-effective for the unequivocal identification of the target species of Brachyplatystoma. They can be utilized by fish processing industries to certify their products, or by government agencies to authenticate products and prevent fraudulent commercial substitutions.
Development and validation of a nomogram to predict protein-energy wasting in patients with peritoneal dialysis: a multicenter cohort study
Authors: Mei Ziwei , Zhu Bin , Sun Xiaoli , Zhou Yajie , Qiu Yuanyuan , Ye Xiaolan , Zhang Hongjuan , Lu Chunlan , Chen Jun , Zhu Hong
Published: June 2023

Background

Protein-energy wasting (PEW) is a common complication in patients with peritoneal dialysis (PD). Few investigations involved risk factors identification and predictive model construction related to PEW. We aimed to develop a nomogram to predict PEW risk in patients with peritoneal dialysis.

Methods

We collected data from end-stage renal disease (ESRD) patients who regularly underwent peritoneal dialysis between January 2011 and November 2022 at two hospitals retrospectively. The outcome of the nomogram was PEW. Multivariate logistic regression screened predictors and established a nomogram. We measured the predictive performance based on discrimination ability, calibration, and clinical utility. Evaluation indicators were receiver operating characteristic (ROC), calibrate curve, and decision curve analysis (DCA). The performance calculation of the internal validation cohort validated the nomogram.

Results

In this study, 369 enrolled patients were divided into development (n = 210) and validation (n = 159) cohorts according to the proportion of 6:4. The incidence of PEW was 49.86%. Predictors were age, dialysis duration, glucose, C-reactive protein (CRP), creatinine clearance rate (Ccr), serum creatinine (Scr), serum calcium, and triglyceride (TG). These variables showed a good discriminate performance in development and validation cohorts (ROC = 0.769, 95% CI [0.705–0.832], ROC = 0.669, 95% CI [0.585–0.753]). This nomogram was adequately calibrated. The predicted probability was consistent with the observed outcome.

Conclusion

This nomogram can predict the risk of PEW in patients with PD and provide valuable evidence for PEW prevention and decision-making.
The conservation value of freshwater habitats for frog communities of lowland fynbos
Authors: Terblanche Naas , Measey John
Published: June 2023

Amphibians are more threatened than any other vertebrate class, yet evidence for many threats is missing. The Cape lowland fynbos (endemic scrub biome) is threatened by habitat loss, and natural temporary freshwater habitats are removed in favour of permanent impoundments. In this study, we determine amphibian assemblages across different freshwater habitat types with special attention to the presence of invasive fish. We find that anuran communities differ primarily by habitat type, with permanent water habitats having more widespread taxa, while temporary water bodies have more range restricted taxa. Invasive fish are found to have a significant impact on frogs with toads most tolerant of their presence. Temporary freshwater habitats are a conservation priority in the area, and their amphibian assemblages represent endemic taxa that are intolerant of invasive fish. Conservation of a biodiverse amphibian assemblage in lowland fynbos areas will rely on the creation of temporary freshwater habitats, rather than a northern hemisphere pond based solution.
Effects of Accountability on Public Policy Implementation in Marsabit County Government
Authors: Malicha Ali Guyo , Ndolo Jackson
Published: June 2023

Socioeconomic development metrics such as economic growth rates, unemployment levels, corruption levels, and poverty rates in Kenya do not correlate with the country's comprehensive policy framework. It seems that policy design and execution aren't going hand in hand. This has been evidenced in the counties report given by the controller of budgets and continued impeachments of county governors due to poor governance cited by the various county assemblies. This study assessed the effects of accountability on implementation of public policy in Marsabit County, Kenya. The study adopted a descriptive research design which helped to describe governance and public policy implementation in Marsabit County. The study targeted 69158 respondents from various urban centres in Marsabit County with a sample size of 384 respondents selected using stratification and simple random sampling and data collect used questionnaire as the instrument. The data were coded and analyzed using SSP. Descriptive and inferential statistics data analysis results were used to reveal the influence of, accountability on policy implementation in public sector in Kenya. The results indicate that the overall model was satisfactory. This means that items on Accountability explain 28.6% of the variations in public policy implementation in the Marsabit county government. It was concluded that accountability practices were major determinants of public policy implementation and that they were the major governance factors that mostly affect effective implementation of policy in the county government. The study recommendations included; that county government should adopt good governance practices in order to improve on policy implementation in their counties.
Plant Spacing Combined with Nitrogen Nutrition Affects Loose Flower Production in Rosa gruss-an-teplitz Under Open Conditions
Authors: Kaur Arshdeep , Singh Ranjit , Singh Parminder
Published: June 2023

The present investigation to study the effect of nitrogen and planting density for open grown roses for loose flower production was carried out at Department of Floriculture and Landscaping, Punjab Agricultural University, Ludhiana during 2020-21. Two years old plants were used for this study which were planted at three different spacings 70 x 100 cm, 70 x 90 cm and 70 x 80 cm. The plants were fertilized with four levels of nitrogen 0 g, 1.5 g, 2.0 g and 2.5 g per plant at monthly interval starting from pruning. The experiment was laid out in FRBD Design with twelve treatments each having three replications. The treatment combination comprising of 2.0 g nitrogen per plant per month with plant spacing 70 x 100 cm resulted in maximum plant height (109.83 cm), plant spread (95.67 cm), flower diameter (6.83 cm), flower weight (3.45 g), number of flowers per plant (389.66), flower yield (0.85 kg) per plant and hence, flower yield (3348.47 kg) per acre. The flowering was recorded earlier in 2.0 g nitrogen under spacing 70 x 100 cm as it exhibited flowering in 64.00 days. The shelf life of flowers was recorded maximum (10.87 hrs) with 1.5 g nitrogen under 70 x 100 cm spacing which was statistically at par with 2.0 g nitrogen under 70 x 100 cm spacing.
Air Layering in Guava (Psidium guajava L.) as Influenced By IBA and Polywrappers
Authors: Singh Navdeep , Bahadur Vijay , Prasad V. M.
Published: June 2023

The experiment was conducted employing randomized block design with three replications, and the study consists of 12 treatment combinations in total using different concentration of Indolebutyric acid (IBA) in liquid, powder and paste form as well as using of white polywrappers (WP) and black polywrappers (BP). The best treatment was T11 with IBA Powder form@ 10000 ppm + BP which showed the highest root and growth parameters. With respect to number of primary roots, length of primary roots, diameter of primary roots, number of secondary roots, length of secondary roots, diameter of secondary roots, and dry weight of roots, T11was found superior. At 90 days after planting,70% success in rooting, 71.02% survival percentage, number of shoots per layer 7.78 and 15.56 number of leaf per plant was significantly (p>0.05) found higher as compared to other treatment combinations. Further, T8 (IBALiquid @ 10000 ppm + BP secured second position whereas minimum values were recorded in T3with IBA Paste @ 5000 ppm + White polywrapper.
Assessment of a Tertiary Hospital’s Systems Thinking Approach Using the World Health Organization Health System Framework in Response to the COVID-19 Pandemic in Nigeria
Authors: Nwatu C. B.
Published: June 2023

Background: The coronavirus disease 2019, (COVID-19) pandemic dealt a catastrophic blow to health systems globally, especially those of middle and low-income-countries, whose health systems were already frail, pre-pandemic. The World Health Organization (WHO) recognizes six building blocks (BBs) for a sturdy health system, whose synergistic interaction, through a systems thinking approach, guarantees optimal and equitable health outcomes for the populace, while shielding them from financial risk. 

Objectives: To showcase a Nigerian tertiary hospital’s response to the COVID-19 pandemic, through the application of systems thinking, to the WHO health systems BBs.

Methods: A questionnaire-based survey (utilizing a Likert scale of 1=very poor; 2=poor; 3=fair; 4=good and 5=excellent) of the hospital-wide efforts, employed by the leadership of the University of Nigeria Teaching Hospital (UNTH) Enugu, utilizing the WHO BBs, during the COVID-19 pandemic, assessed the perceived impact of the individual BBs on the hospital system. Eighty key stakeholders (Females=55%), heads of departments and supervisors, comprising various categories of medical personnel, overseeing twenty critical service areas of the hospital undertook the survey.

Results: Leadership/Governance ranked highest in impact among the BBs (68.6%), with the availability of Medical products/Technology (65.9%), and Service delivery (64.4%) trailing closely at second and third, respectively. Perceived robustness and overall motivation of the Health Workforce was least ranked at 57.1%, closely followed by Healthcare Financing (58.2%) and Health Information Systems (61.9%).

Conclusion: At an average cumulative score of 62.7% for all the BBs, the UNTH leadership may be adjudged to have performed creditably in their efforts at COVID-19 containment. Staff welfare should be enhanced, to ensure a well-motivated staff which will likely translate to improved service delivery.
ISOMORFISMO INSTITUCIONAL: ANÁLISE DE RELATOS INTEGRADOS DE EMPRESAS ABERTAS NA ITÁLIA E NOS ESTADOS UNIDOS
Authors: Correia Thamirys de Sousa , Santos Rayane Farias dos , Paiva Simone Bastos
Published: June 2023

Este estudo teve como objetivo analisar os aspectos isomórficos para institucionalização presentes nos Relatos Integrados de Empresas de Mercado Aberto na Itália e nos Estados Unidos. Para tanto, foi utilizado o método da análise de conteúdo categorial cujo foram analisadas três empresas italianas e três americanas participantes do Projeto Piloto para Relato Integrado, no período de 2012 a 2018. Constatou-se que há uma tendência ao isomorfismo institucional perante a amostra utilizada, assim como as empresas italianas apresentaram um quantitativo maior de termos relacionados as categorias propostas ao comparar com as empresas americanas, fato que ocorreu no nível organizacional e de campo. As evidências demostraram a presença de isomorfismo institucional, em particular, quando se trata do grau de dependência entre as organizações, da confiança em credenciais acadêmicas para a escolha do pessoal gerencial e funcional, da centralização do fornecimento de recursos e da influência de órgãos de Estado.
PROGRAMA NOTA MT: REFLEXOS NA ARRECADAÇÃO E NO COMBATE À SONEGAÇÃO FISCAL NO ESTADO DE MATO GROSSO
Authors: Correa Loana Bonfim , Nunes Edinéia Souza , Santos Josiane Silva Costa dos , Servilha Graziele Oliveira Aragão , Hoffmann Arilson
Published: June 2023

O estudo tem por objetivo evidenciar se o programa Nota MT influencia na arrecadação e na redução da sonegação fiscal do estado de Mato Grosso (MT). Esta pesquisa classifica-se quanto aos objetivos como descritiva, com a abordagem quantitativa e quanto ao procedimento técnico documental. A coleta de dados ocorreu via ofício, e-mail, e relatórios divulgados no site da Sefaz-MT, período de análise de dados foi de julho de 2018 a 11 de setembro de 2020. Os resultados indicaram que apesar dos impactos causados pela pandemia, o programa Nota MT influenciou na arrecadação do Estado e com o auxílio dos consumidores, o combate à sonegação fiscal tornou-se mais exequível. Ainda assim, sugere-se a realização de estudos futuros a fim de analisar o desempenho do programa no período pós pandemia.
Explorando a Economia Circular: Perspectivas Internacionais em Foco
Authors: Silva Ferreira Alison , Batista Moreira Nayara , Dias Filho José Maria
Published: June 2023

Este trabalho tem por objetivo investigar o perfil da produção científica mundial acerca da Economia Circular, tomando por base os principais periódicos das áreas de economia, engenharia, contabilidade e negócios. Para tanto, foi utilizada a técnica de análise bibliométrica em 80 periódicos durante os anos de 2015 a 2019. Foram verificados 281 artigos que corresponde a 0,61% de toda a publicação do período. Os resultados obtidos sugerem que as discussões em torno da Economia Circular têm avançado no decorrer dos anos. Porém, não foram encontrados artigos publicados em journals de contabilidade, economia, finanças e negócios, havendo uma necessidade de maior engajamento dessas disciplinas. Estima-se que a concentração de publicações acerca de EC está localizada especialmente na China e na Europa. O Brasil, por sua vez, ficou ranqueado em 12° lugar. No geral, os trabalhos utilizaram, principalmente, abordagens de estudos de caso e aplicações de experimentos. Os achados reforçam e corroboram com literatura anterior, principalmente devido a possibilidade de verificar quais tipos de pesquisas sobre EC vem sendo empregadas pelo mundo, auxiliando pesquisadores a identificarem lacunas de pesquisa para aplicação prática e a agentes de mercado identificarem o panorama atual das novas práticas produtivas circulares no contexto de diferentes negócios.
Pressure ulcer in critical patients affected by Covid-19: prone position protocol / Lesão por pressão em pacientes críticos acometidos pela Covid-19: protocolo de prona
Authors: Lima Bruna , Santos Karina de Freitas , Oliveira Cristine Rosa Sepúlveda
Published: June 2023

Objetivo: avaliar a incidência de lesão por pressão, por localização, o risco de desenvolvimento pela escala de Braden e o uso de protetores, em pacientes críticos em protocolo de prona com Covid-19, em um hospital em Belo Horizonte. Método: trata-se de um estudo observacional, quantitativo, descritivo e prospectivo. Os dados foram coletados através de prontuário eletrônico, no sistema MV, e no sistema AGEIS Nutrition, durante o período entre 12 de abril de 2021 e 13 de agosto de 2021. Resultados: no total de 251 prontuários analisados de pacientes adultos, evidenciou-se 42,2% apresentaram lesão por pressão, sendo a localização mais frequente em zigomático com 50,9%. A maioria dos pacientes utilizaram espuma multicamadas (92%) e 51,4% de pacientes apresentaram risco elevado de lesão. Conclusão: a incidência de lesão por pressão foi de 42,2%. A presença de comorbidades e o risco elevado na escala de Braden podem ter contribuído para a considerável porcentagem.
Fact or Artifact in Inferior ST Elevation—Avoiding Misdiagnosis and Missed Diagnosis
Authors: Yin Zhao-Wei , Li Pan , Chen WenBiao
Published: June 2023

This case report describes a patient in their 60s with a history of hypertension who experienced sudden chest pain radiating to the back and sweating for 2 hours without relief.
Obtaining and Paying for Home Care—Navigating Patients Through the Complex Terrain of Home Care in the US
Authors: Sterling Madeline R. , Grabowski David C. , Shen Megan J.
Published: June 2023

This essay describes the challenges of home care in the US and advocates for incorporating elements of advance care planning and building navigation systems for obtaining and managing care.
What Should I Know About Medication Deprescribing?
Authors: Wu Peter E. , Lee Todd C. , McDonald Emily G.
Published: June 2023

This JAMA Internal Medicine Patient Page describes the process of slowly and carefully cutting down on unnecessary medications with the guidance of a health care professional.
Patterns in Child Health Outcomes Before and After the COVID-19 Outbreak in India
Authors: Ko Soohyeon , Kim Rockli , Subramanian S. V.
Published: June 2023

This cross-sectional study examines prepandemic-to-postpandemic changes in mortality, nutrition and feeding practices, anthropometry, vaccination, and other measures in a sample of children from the Indian National Family Health Survey.
Posterior Reversible Encephalopathy Syndrome in a Child With Renovascular Hypertension
Authors: Chavan Ajay , Paliwal Vimal Kumar , Singh Vivek
Published: June 2023

A 6-year-old child presented with headache for 1 month and seizures followed by altered consciousness for 1 day. He had new-onset daily occipital headache for 1 month of mild to moderate severity and pulsating character. What is your diagnosis?
Thromboinflammatory challenges in stroke pathophysiology
Authors: Szepanowski R.D , Haupeltshofer S , Vonhof S.E , Frank B , Kleinschnitz C , Casas A.I
Published: June 2023

Despite years of encouraging translational research, ischemic stroke still remains as one of the highest unmet medical needs nowadays, causing a tremendous burden to health care systems worldwide. Following an ischemic insult, a complex signaling pathway emerges leading to highly interconnected thrombotic as well as neuroinflammatory signatures, the so-called thromboinflammatory cascade. Here, we thoroughly review the cell-specific and time-dependent role of different immune cell types, i.e., neutrophils, macrophages, T and B cells, as key thromboinflammatory mediators modulating the neuroinflammatory response upon stroke. Similarly, the relevance of platelets and their tight crosstalk with a variety of immune cells highlights the relevance of this cell-cell interaction during microvascular dysfunction, neovascularization, and cellular adhesion. Ultimately, we provide an up-to-date overview of therapeutic approaches mechanistically targeting thromboinflammation currently under clinical translation, especially focusing on phase I to III clinical trials.
Does littoral substrate affect macroinvertebrate assemblages in Mediterranean lakes?
Authors: Mavromati Efpraxia , Kemitzoglou Dimitra , Tsiaoussi Vasiliki
Published: June 2023

The objective of this study was to investigate the effects of substrate type in macroinvertebrate assemblages in Mediterranean lakes. Samplings have taken place in the littoral zone of 21 lakes in Greece, between 2015 and 2018. We compared benthic macroinvertebrate assemblages among three substrate types of their littoral zones; sandy, covered with macrophytes and stony substrate. Benthic macroinvertebrate assemblages at sites with extended macrophyte cover differed only slightly in composition and abundance from the ones found in stony and sandy substrates. Coenagrionidae were indicative of sites covered with macrophytes and Oligochaeta and Erpobdellidae were representative of stony substrates. The type of substrate proved to be a statistically significant factor influencing the number of benthic macroinvertebrate taxa, the relative abundance of Oligochaeta and the relative abundance of Odonata. In the context of designing site-adapted management measures, priority could be given to the conservation and restoration of aquatic vegetation in lake littoral zones, which host rich macroinvertebrate assemblages with abundant taxa of Odonata.
Evaluation of a Community COVID-19 Vaccine Ambassador Train-the-Trainer Program
Authors: Corley Alexandra M. S. , Gomes Stacey M. , Martin Keith J. , Watkins Sharon , Lindsey Kendal , Frenck Robert W. , Mitchell Monica J. , Rule Amy R. L. , Crosby Lori E.
Published: June 2023

Racially minoritized groups are more likely to experience COVID-19 vaccine hesitancy and have lower vaccination rates.  As part of a multi-phase community-engaged project, we developed a train-the-trainer program in response to a needs assessment. “Community vaccine ambassadors” were trained to address COVID-19 vaccine hesitancy. We evaluated the program’s feasibility, acceptability, and impact on participant confidence for COVID-19 vaccination conversations. Of the 33 ambassadors trained, 78.8% completed the initial evaluation; nearly all reported gaining knowledge (96.8%) and reported a high confidence with discussing COVID-19 vaccines (93.5%). At two-week follow-up, all respondents reported having a COVID-19 vaccination conversation with someone in their social network, reaching an estimated 134 people. A program that trains community vaccine ambassadors to deliver accurate information about COVID-19 vaccines may be an effective strategy for addressing vaccine hesitancy in racially minoritized communities.
Effects of nitrogen and water addition on soil carbon, nitrogen, phosphorus, sulfur, and their stoichiometry along soil profile in a semi-arid steppe
Authors: Niu Guoxiang , Zhong Buqing , Wang Ruzhen , Jin Yiqian , Wang Yinliu , Lü Xiaotao , Jiang Yong , Huang Jianhui
Published: June 2023

Purpose

Although past studies have found well-constrained soil carbon (C)/nutrient ratios, the effects of increased nitrogen (N) and water inputs on these ratios across soil depths have rarely been assessed in semi-arid grasslands.

Methods

In this study, we evaluated the contents of total C, N, phosphorus (P), sulfur (S), and their stoichiometric ratios in a 0–80 cm soil profile following 13 years of successive N (at rates of 5 and 15 g m−2 yearr−1) and water addition (180 mm per growing season) in a semi-arid grassland of the Mongolian Plateau.

Results

In the 0–10 cm soil layer, long-term N addition tended to increase total C and N contents but decreased soil total P and S contents compared to the control. The effects of N addition, as observed in 0–10 cm soil, however, were not consistent with that in the deep 10–80 cm soil layers. Water addition increased the total C, N, and P contents across the entire soil profile but increased total S content only in 0–40 cm soil. Moreover, the combined addition of N and water generally had stronger effects on the four elements across the whole soil profile. For the stoichiometry of the four elements, a low rate of N addition (5 g m−2 year−1) increased soil C:N ratios and decreased soil P:S ratios in the 0–80 cm soils, but a high rate of N addition (15 g m−2 year−1) produced the opposite effect. Both N addition rates resulted in an increase in the soil C:P, C:S, N:P, and N:S ratios. Similarly, in plots that received water, water addition alone decreased the soil C:N ratios, while N addition caused higher fluctuations in these six elemental ratios. However, there was no consistent pattern of change in any one ratio, independent of the addition of water, when taking into account N addition rates and soil depths.

Conclusion

Our findings showed that the effects of N addition on soil total C, N, P, and S contents and their stoichiometric ratios were highly influenced by the rate of N addition and the depth of soil, and that these effects could be modulated by increasing precipitation. These results need to be carefully considered while managing the ecological environment in semi-arid steppes.
Patterns of Ips cembrae (Herr) infestation on trap and standing trees of European larch (Larix decidua Mill.)
Authors: Špoula Jakub , Kula Emanuel
Published: June 2023

The large larch beetle, Ips cembrae, is a significant pest causing the death of larch. In 2020, the attack density of I. cembrae on larch trap trees and standing trees was evaluated using sample sections placed along the trunk. As a defensive measure against I. cembrae, trap trees were highly effective in both spring and summer. The attack density increased with increasing trap tree surface area/volume. Galleries were established evenly throughout the entire trunk including the thin upper portion. When the number of trap trees was low and their capacity full, a continual aggregation of adults occurred due to pheromone communication, leading to attacks on healthy standing trees in the immediate vicinity. It was found that I. cembrae attacked standing trees from the trunk base, with a continual colonization of the stem up to 70% of the tree height in a time-differentiated progression of development stages. The attack density of I. cembrae on standing trees was up to 40% lower than on the trap trees.
Investigation of collapse pressure in layered formations based on a continuous anisotropic rock strength criterion
Authors: Gao Fei , Guo Runsheng , Wang Wen , Zhang Yan , Zheng Shuangjin
Published: June 2023

Wellbore instability severely constrains the exploration and development of shale gas. In order to evaluate the impacts of anisotropy and water on wellbore instability, three different types of criteria are fitted to strength data of LMX shales with different moisture contents. A new model of transversely isotropic borehole stability considering compliance incremental tensor induced by natural fractures is proposed, then a more preferred drilling direction is performed by the new model. Results indicated that, Pariseau’s model is more attractive in predicting shale strength, including the difference of strength between vertical bedding and parallel bedding. Based on Pariseau’s model, the prediction accuracy of shale strength is improved by 33.04%. The Pariseau’ model gives a disparate collapse pressure from Jæger’s weak plane criterion, the most unstable drilling area shifts from northeast and southwest to the central area corresponding to relatively lower inclination. The collapse pressure only decreased by 0.55 MPa with considering the anisotropy of elastic parameters, but the strength criteria have a distinct influence. Compared with the results predicted by Jæger’s plane of weakness, the collapse pressure increased by 8.55 MPa using Pariseau’ model. Besides, invasion of water in bedding plane will aggravate borehole instability, especially in late drilling period, collapse pressure for the vertical wellbore increased by 6.35 MPa. Shale strength depends not only on the hydrostatic pressure and orientation angle, but also on the water content, which should be considered in mud weight design and well trajectory optimum.