bluuebunny/crossref_metadata_2025 huggingface dataset:
Pseudomonas aeruginosa: A Persistent Pathogen and Current Approaches to Treatment- Microbiology
Authors: Kumar Nitish , Vasundhara Vasundhara , Kumar Chavan Sandeep
Published: June 2023

Pseudomonas aeruginosa (P. aeruginosa) represents an important bacterial pathogen, mainly because it may infect immunocompromised hosts, hospital patients, and people with cystic fibrosis (CF). Antimicrobial resistance has risen due to monitoring nosocomial P. aeruginosa infections, with tendencies toward model drug and carbapenem resistance. Some of the mechanisms of antimicrobial resistance include the downregulation of outer membrane porins, -lactamases, and multidrug efflux pumps. Toxins that be secreted and can build BioFlim (BF) are examples of virulence mechanisms. Effective therapy of infection caused by P. aeruginosa requires early delivery of the appropriate antibiotic medications, source control measures, and, where possible, prevention. Antibacterial de-escalation is supposed to be considered within patients by a positive clinical response, particularly as antibacterial susceptibilities were identified. Less common antibacterials, including Colistin, may be needed to treat multidrug-resistant P. aeruginosa, although additional anti-pseudomonal antibacterials should become accessible soon
SARS-CoV-2 Vaccination IgG Antibody Responses in Patients with Hematologic Malignancies in a Myeloid Enriched Cohort: A Single Center Observation
Authors: Hoff Fieke W. , Goksu Suleyman Y. , Premnath Naveen , Patel Prapti A. , Ikpefan Ruth , Kaur Gurbakhash , Vusirikala Madhuri , Bat Taha , Chen Weina , Geethakumari Praveen Ramakrishnan , Anderson Larry D., Jr , Awan Farrukh T. , Collins Robert H. , Weinberg Olga K. , Muthukumar Alagarraju , Chung Stephen S. , Madanat Yazan F.
Published: June 2023

Objective. Patients diagnosed with hematologic malignancies are at increased risk for severe SARS-CoV-2 infection. We evaluated the serological IgG response following two doses of the SARS-CoV-2 vaccine in patients with hematologic malignancies.

Methods. Patients treated at UT Southwestern Medical Center with a diagnosis of a myeloid or lymphoid neoplasm were included. SARS-CoV-2 vaccination response was defined as a positive quantifiable spike IgG antibody titer.

Results. Sixty patients were included in the study and 60% were diagnosed with a myeloid neoplasm. The majority (85%) of the patients with a myeloid malignancy and 50% of the patients with a lymphoid malignancy mounted a serological response after receiving two doses of the vaccine.

Conclusion. Vaccination should be offered irrespective of ongoing treatment or active disease. Findings require validation in a larger cohort of patients.
„Az önkormányzás nem cél, hanem eszköz"
Authors: Pap Anna Gyöngyi
Published: June 2023

Pálné Kovács Ilona jogász, politológus főbb kutatási területei közé tartozik az önkormányzati rendszer, a helyi, illetve az európai regionális politika. Helyi kormányzás Magyarországon című monográfiájában ezeket a témaköröket járja körül hazai vonatkozásban, interdiszciplináris megközelítésben. A helyi-területi kormányzást, valamint az önkormányzati rendszert jogi, gazdasági és politikai szempontok alapján vizsgálja. Az elméleti alapvetés mellett részletesen kitér a helyi/regionális politikára, az állam és az önkormányzatok viszonyára, a magyar közigazgatás történeti fejlődésére, az önkormányzati rendszer formálódására, valamint a helyi kormányzás tekintetében várható jövőbeni változások irányaira.
„És ha méltó a ház, szálljon a ti békességtek reá”
Authors: Cserép Emese
Published: June 2023

A Kléruskongregáció által 2020-ban kiadott, A plébániai közösségek lelkipásztori konverziója az Egyház evangelizáló küldetésének szolgálatában című dokumentum célkitűzése, hogy az egyház egyik fő feladatához, az evangelizációhoz időszerű iránymutatásokat adjon. A vatikáni instrukció az egyházjogi keretekhez igazodva igyekszik szembenézni a jelenkor kihívásaival, és az Ige hirdetésének megreformálására buzdít. A küldetés elsődleges fórumaként a plébániát jelöli meg, melynek hatékonyabb működéséhez időszerűbb, kreatívabb utakra hívja az intézmény minden tagját. A dokumentum üdvösnek tartja a laikusok szerepvállalását, amely nélkül az egyház átfogó evangelizációs tevékenysége elvesztené lendületét. A plébánia struktúrájára és tagjaira is kitér, és igyekszik megoldásokat kínálni olyan – napjainkban égető – problémákra, mint a papok adminisztrációs túlterheltsége vagy egy közösség lelkipásztori ellátásának átmeneti hiánya.
Conocimiento de los adultos mayores en la prevención de hipertensión arterial
Authors: Gavilanez Remache Pablo Andrés , Guallichico Martha
Published: June 2023

La presente investigación permitió identificar el conocimiento que poseen los adultos mayores sobre la prevención de hipertensión arterial, tomando en cuenta las altas tasas de morbilidad en el mundo se puede afirmar que esta patología va en aumento Se realizó una investigación tipo cuantitativa  a nivel descriptivo con corte transversal que nos permitió medir el nivel de conocimientos de una población de adultos mayores seleccionada a través de criterios de inclusión y exclusión a través del muestreo por conveniencia, en donde la encuesta fue el instrumento óptimo para la recolección de datos, elaborada previamente con 13 preguntas cerradas y validada por medio de la formula estadística de Alfa de Cronmbcah, posterior a su aplicación se tabularon datos de forma manual obteniendo frecuencias de respuesta como resultado, cabe resaltar que la investigación respeto en todo momento los aspectos éticos de la investigación médica en humanos establecidos en la declaración de Helsinki. Se logró identificar que un 75% de los adultos mayores conocen sobre la HTA, así mismo su dieta está basada en frutas, verduras y vegetales evitando los altos consumo de sal, alcohol y cigarrillo, sin embargo, los mismo no asisten a controles frecuentemente, más de la mitad realizan sus chequeos médicos una vez a año. El conocimiento es la base de la prevención, si bien el adulto mayor es un ente vulnerable por su condición fisiológica ante el padecimiento de HTA, el mismo puede a través de hábitos y rutinas saludables mejorar evidentemente su calidad de vida.
Adolescentes: promiscuidad y relaciones sexuales una mirada desde la psicología clínica
Authors: Ortiz Pantoja Vanessa Lilibeth , Verdezoto García Mirian Isabel , Villacís Jácome Juan Enrique , Baquero Adriano Jessica Lizbeth
Published: June 2023

El presente estudio pretende comprender las motivaciones y experiencias que tienen los adolescentes para actuar de manera promiscua y/o tener relaciones sexuales desprotegidas, identificando estos comportamientos, así como los factores socioculturales que estarían influyendo para la permanencia de este fenómeno. El diseño del estudio es cualitativo, en base a una muestra homogénea de diez adolescentes hombres y mujeres de etapa tardía, a quienes se les aplicó entrevistas semiestructuradas. Para el análisis de los resultados se categorizó en: conducta sexual, factores socioculturales y reflexiones personales de los participantes. Los resultados muestran que el aprendizaje social y posterior actuar sexual de los adolescentes, dependen del deseo por agradar, el nivel de intimidad, confianza, admiración que perciben de los diversos modelos con los que interactúan; así, el agente socializador más relevante es la pareja sentimental, seguida por los padres y la institución educativa, dos factores que aún hoy otorgan una educación sexual precaria. Percibiendo el tabú permanente que aún rodea a la sociedad quiteña sobre temas de sexualidad, permitiendo mantener a los adolescentes en una condición de vulnerabilidad y desconocimiento, se concluye que la importancia de la educación sexual radica en la integralidad de la sexualidad humana, teniendo en cuenta que no únicamente se limita a lo físico y reproductivo, y que el aprendizaje humano comienza desde su nacimiento.
Physical Activity Compliance to American Cancer Society Recommendations Amongst Hematopoietic Stem Cell Transplant Survivors
Authors: Mead L.E. , Kelly D.L. , Dahl W.J. , Colee J.C. , Merchant Asim , Weaver M.T. , Wingard John R. , Farhadfar N.
Published: June 2023

Background and objectives:

The aims of this study were to determine the extent to which hematopoietic cell transplantation (HCT) survivors adhere to the American Cancer Society recommendations for weekly physical activity and identify potential demographic and transplant characteristics associated with the lack of compliance.

Methods:

This cross-sectional study included adults who had undergone HCT and were at least 1 year post transplantation. Physical activity was assessed using the screening tool of the Block 2014. The type of activity, frequency, and intensity were converted into the metabolic equivalent of task (MET) scores (0–499.0 MET min/week, inadequate activity; 500–1000 MET min/week, adequate activity; >1000 MET min/week, highly vigorous activity).

Results:

Participants (n = 81) reported a median MET score of 153 min/week, and 83% failed to reach the physical activity guideline of >500 MET min/week. Only 17.3% met the ACS recommendations, with three reporting above 1000 MET min/week. Median daily moderate and vigorous physical activity minute totals were 18.0 and 5.9 min/d, with 85.2% and 60.5% of participants involved, respectively. The median total physical activity energy expenditure was 744 kcal/d. Only race was associated with MET score, with Whites reporting higher MET scores.

Conclusion:

Most HCT survivors assessed in this study did not meet the ACS physical activity recommendations. These findings reinforce the need to incorporate screening for physical activity into HCT survivorship care, offer counseling to those who do not meet the recommended levels, and encourage a physically active lifestyle among HCT survivors.
Effectiveness, Safety, and Cost Implications of Outpatient Autologous Hematopoietic Stem Cell Transplant for Multiple Myeloma
Authors: Marini Jessica , Maldonado Andy , Weeda Erin , Neppalli Amarendra , Hashmi Hamza , Edwards Kathy
Published: June 2023

Background and objective:

Autologous hematopoietic stem cell transplant (aHCT) has become standard care for patients with multiple myeloma (MM). Outpatient aHCT with high-dose melphalan conditioning has reduced costs and length of hospital stay. This study aimed to highlight the effectiveness, safety, and cost implications of outpatient vs inpatient aHCT at a tertiary academic medical center, as well as the utility of growth factor use in these patients.

Patients and methods:

Using an institutional HCT database, a total of 100 patients undergoing aHCT for MM were identified; 50 patients who underwent aHCT in the outpatient setting (chemotherapy and stem cell infusion followed by inpatient admission if needed) were compared with 50 patients in the inpatient setting (chemotherapy and stem cell infusion followed by discharge to outpatient setting). Patients were excluded if the melphalan dose was less than 200 mg/m2. Outcomes assessed through retrospective chart review included time to engraftment, incidence of infection, febrile neutropenia, growth factor use, and total length of inpatient stay through day +100.

Results:

Time to neutrophil and platelet engraftment was shorter in the outpatient group than in the inpatient group (14 vs 16 days and 19 vs 21 days, respectively; P < 0.001). Median length of hospital stay was also shorter in the outpatient group (8.5 vs 15.5 days, respectively; P < 0.001).

Ninety percent of the outpatient group required admission for neutropenic fever, and 60% of these patients received growth factor support starting at a median of 9 days after stem cell infusion, for a median duration of 4 days. Compared to 16 patients who did not receive growth factor support, these patients had a significantly shorter time to neutrophil recovery (13 days with vs 15 days without growth factor, P = 0.02) and no difference in the total length of hospital stay (8 days with vs 10 days without growth factor, P = 0.43).

Conclusion:

For adult patients with MM undergoing aHCT, the outpatient setting is safe and reduces the total length of hospital stay and thus overall transplant costs. Growth factor support for patients with febrile neutropenia may not reduce length of stay for subsequent hospitalizations.
Post-Autologous Hematopoietic Cell Transplant Care in the “Home Sweet Home” Setting: A Treatment Paradigm Shift
Authors: Kharfan-Dabaja Mohamed A. , Roy Vivek , Murthy Hemant , Fischer Deborah , Mohty Razan , Greathouse Ashley , Brown Alethea , Moreno Kathryn , Godsey Emily , Higginbotham Jennifer M. , Bartholomew Ashley , Jackson Alexis , Torres-Guzman Ricardo A. , Forte Antonio J. , Ailawadhi Sikander , Dronca Roxana , Maniaci Michael
Published: June 2023

Background:

Multiple myeloma (MM) is the second most common hematologic malignancy, with 34,470 estimated new cases in 2022. High-dose therapy followed by autologous hematopoietic cell transplantation (auto-HCT) remains a standard treatment for MM even in the era of novel therapies. This is usually performed in hospital-based settings, either in the inpatient or outpatient units. Advanced Care at Home (ACH) represents a virtual hybrid hospital-at-home program that combines a virtual provider-staffed command center with a vendor-mediated supply chain capable of delivering high-acuity care in the comfort of the patients’ own homes. In our program, we used the existing ACH platform to deliver post-HCT care for recipients of auto-HCT.

Patients and methods:

Four patients (female = 2, 50%) with MM, with a median age of 60 (range, 40–74) years, were admitted to the inpatient Blood and Marrow Transplant (BMT) unit. The conditioning regimen consisted of melphalan 200 mg/m2, administered on day –2. All patients received stem cell infusion (day 0) in the inpatient setting, with a median dose of 3.64 (range, 2.92–8.22) × 106/kg CD34 cells.

Results:

Patients were discharged to their homes after completing the infusion on day 0 or day +1 at the latest. Postinfusion care was provided by the ACH team in coordination with the BMT team. The median time intervals to absolute neutrophil count and platelet engraftment were 12 (range, 11–13) and 11 (range, 9–16) days, respectively. All patients were successfully discharged from the ACH program at a median of day +14 (range, day +14 to day +15).

Conclusions:

Our results highlight the feasibility of delivering post-HCT care for auto-HCT recipients in the home setting and confirm the generalizability of this approach.
Environmental Geochemistry and Heavy Metal Assessment in Soils, Surface and Groundwater from Eastern Niger-Delta, Nigeria using Multivariate Pollution Indices
Authors: Amadi, A.N.  , Olasehinde, P.I.  , Yisa, J.  , Shaibu, I.  , Okoye, N.O.
Published: June 2023

In recent times, there have been increasing interests regarding heavy metal contaminations in the environments, apparently due to their toxicity and perceived persistency within the aquatic systems. Land and water are precious natural resources on which rely the sustainability of agriculture, industrialization and the civilization of mankind. They have been subjected to severe exploitation and contamination due to anthropogenic activities resulting from industrial effluent, refuse dumps, gas flaring, oil spillage and petroleum refining leading to the release of heavy metals into the environment. The results of the analyses indicate a low pH (3.84 – 7.74) and high concentrations of electrical conductivity (28.00 – 752.00), chloride (12.00 – 721.00) and heavy metals in the decreasing order of: Fe > Ni > Cu > Zn > Mn > Cd > V > Co > Pb > Cr > As > Hg. The heavy metal pollution index revealed that the metal pollution in the soil and water ranged from slightly polluted to very highly polluted. The poor sanitary condition coupled with the high degree environmental abuses in terms of oil spillage, gas flaring and industrial effluent in the area are responsible for the low pH, wide range in the concentration of EC, TDS, Chloride, E.coli, total coliform and  heavy metals in the soil and water system in the area. Good sanitation, use of welllined soakaway, treatment of industrial effluent before discharge and putting an end to gas flaring and oil spills are advocated. The use of environmentally friendly techniques such as bioremediation and phytoremediation in remediating the contaminated soil and water in the area is recommended.
Uses of seismic refraction tomography in investigation of groundwater potential in Kaduna millennium city, Kaduna Nigeria
Authors: Shaibu, I.  , Udensi, E. E.  , Usman, D. A.
Published: June 2023

Seismic refraction tomography is unique in the sense that shot are taken at every receiver position along the spread. In that way, it becomes possible to conduct both forward and reverse shooting simultaneously along the profile lines. Therefore, every point within the subsurface along the profile lines is probed by both forward and reversed shots. This leads to what one might call the scanning of the subsurface. The data were processed with ReflexW software and a conventional forwardand reversed travel time curve was plotted for each profile lines. Thereafter joint inversion of the travel time picks was carried out. This resulted in the generation of an iterative model, which was used to generate tomographic sections. The result of seismic refraction tomography showed lateral and vertical variation in velocity along most of the profile lines, thereby giving a true image of velocity distribution, both vertically and laterally within the subsurface. Refraction Tomography gave accurate depth and thickness of the overburden along the profile and to delineate aquifer potentialin the basement topography. The aquifer is estimated to be around 45m to 60m along the entire profile line
Assessment of Phytochemicals, Antioxidant and Antimicrobial Activities of Aqueous Ethanol Extract and Fractions of Azadirachta indica Stem Bark
Authors: Adaramola Feyisara , Adewole Samuel , Adewole Oluwaseun
Published: June 2023

In this study, the aqueous ethanol extract of Azadirachta indica stem bark was obtained by Soxhlet extraction and partitioned into different solvents. The extract and fractions were then assessed for their phytochemical contents, antioxidant, and antimicrobial activities. The results showed that saponins, flavonoids, phenol, and tannins were present in all the samples. Also, the ethanol extract had the highest flavonoid (281.15 mgQE/g), phenolic (714.82 mgGAE/g), and tannin (156.54 mgTAE/g) contents, as well as the highest DPPH scavenging activity (95.71%) and total reducing power (1.27). However, among the fractions, butanol fraction showed the highest contents of flavonoids (235.20 mgQE/g), phenolics (413.42 mgGAE/g) and the highest DPPH scavenging activity (93.87 %) while the highest tannin content (86.90 mgTAE/g) and total reducing power (1.06) was observed in the ethyl acetate fraction. The lowest concentration of flavonoid (34.60 mgQE/g) and lowest antioxidant activity was obtained for the hexane fraction while lowest contents of phenolics (102.32 mgGAE/g) and tannins (41.21 mgTAE/g) were both observed in the water-soluble fraction. The most active fraction against both Staphylococcus aureus and Enterobacter cloacae was ethyl acetate. Meanwhile, the ethanol extract, hexane fraction, and water-soluble fractions showed the highest activity against Candida albicans, Salmonella typhi, and Escherichia coli, respectively. This research reveals that the stem bark of Azadirachta indica contains notable antioxidant and antimicrobial properties, making it a promising source for developing potent therapeutic drugs and functional foods.
Oncocytic Cystic Lesions of False and True Vocal Cords: An Uncommon Occurrence
Authors: Gharib Masoumeh , Shahraki Mohadeseh
Published: June 2023

Introduction: Oncocytic cysts of the larynx are benign, uncommon, and slow-growing lesions that usually occur in elderly people, especially in those with a history of smoking and chronic irritation. These lesions cause various clinical symptoms depending on their location and size, requiring physicians to consider a wide range of symptoms. Case Presentation: Here we present two men who were referred to us because of prolonged voice hoarseness. Conclusions: Medical assessments led us to the diagnosis of oncocytic cysts in the false and true vocal cords. Both patients were followed up after removing their laryngeal cysts and have had no clinical complaints since then.
The Effect of Eight Weeks of Resistance Training and Testosterone Enanthate Consumption on TNF-α and IL-6 Genes’ Expression in the Kidney Tissue of Female Wistar Rats
Authors: Molaei Khadijeh , Mirzayan Shanjani Sanaz , Gorzi Ali , Kazemzadeh Yaser , Banaeifar Abdolali
Published: June 2023

Objectives: This study aimed to evaluate the effect of testosterone enanthate anabolic steroid on the gene expression of inflammatory factors in the kidney tissue of female rats following eight weeks of resistance training. Methods: Twenty-one female Wistar rats weighing 200 ± 20 g, aged eight weeks, were prepared from the Iran Pasture Institute. Following a week for acclimatization, the rats were randomly divided into three groups: control (n = 7), training + placebo (n = 6), and training + testosterone enanthate (n = 8). Resistance training included five days a week of climbing a 1-meter ladder with 26 stairs while bearing weights and two days of rest. In the first week, the weights were equal to 40% of the rats’ body weight. In the following weeks, the weight was increased by 20% per week. The rats were weighed two times a week. In the testosterone group, the rats were injected with 20 mg of testosterone enanthate thrice a week. Forty-eight hours following the last training session and testosterone injection, kidney tissue samples were collected to determine the gene expression of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) using real-time PCR. Results: The results showed that testosterone consumption significantly increased the gene expression of TNF-α and IL-6 in female rats undergoing testosterone and resistance training (P = 0.001). Conclusions: The findings of this study demonstrated that using testosterone increased inflammatory factors in the kidney tissue of female Wistar rats.
Having the Resilience to an Ever-Changing Business Environment Through Strategic Collaboration Supported by Digital Innovation
Authors: Hidajat Saiful , Setiawan Margono , Rohman Fatchur , Hussein Ananda Sabil
Published: June 2023

Purpose-This research aims to find out how a company can be resilient to an ever-changing business environment through the development of collaboration strategies and digital innovation to improve business performance and to find out which is more dominant in adapting to an ever-changing business environment to improve business performance, whether collaboration strategies or digital innovations? Research Design-This research uses a quantitative approach. Observations were made in a cross-section/one-shot, in 2022. The population of this research was the ISP industry in Indonesia, which amounted to 474 companies, and the unit ofobservation was the top management. Samples were taken from as many as 240 respondents. Testing the causality hypothesis in this research used Structural Equation Modelling (SEM).Results -The results of this research indicate that the business environment has a significant indirect effect on business performance through collaboration and digital innovation strategies, while the direct influence of the business environment on business performance is not significant. The effect of mediating collaboration strategies on the relationship between the business environment and business performance is more dominant than the mediating effect of digital innovation. Conclusion -By developing and implementing digital collaboration strategies and digital innovation to adapt to an ever-changing business environment, making changes in the business environment does not have a direct effect on business performance, so companies will have the resilience to an ever-changing business environment the business environment, and because collaboration strategies have a more dominant influence than digital innovation, then companies should prioritize collaboration strategies that are supported and complemented by digital innovation.
پيش‌گيری رشدمدار از خشونت علیه اطفال در افغانستان
Authors:   کادر علمیِ دیپارتمنت قضایی – څارنوالی،‌ پوهنځی‌ حقوق  و علوم سیاسی، پوهنتون غالب، هرات، افغانستان, وحیدی دکتر عبدالملک
Published: June 2023

خشونت علیه اطفال در جوامع مختلف دیده می¬شود؛ اما در افغانستان‌‌ به دلیل شرایط ناگوار اجتماعی، اقتصادی، سیاسی، فرهنگی و به‌خصوص ضعف فرایندهای آموزشی و تربیتی، این پدیده بیش‌تر بوده و پیامدهای ویران‌گری بر جای می¬گذارد. پرسش این است که در برابر امواج روز‌افزون خشونت علیه اطفال، چه تدبیری می¬توان اندیشید و کدام سازوکار پیش‌گیرانه را می¬توان برای کاهش خشونت علیه اطفال، اتخاذ کرد؟ پاسخ به این پرسش، مهم است؛ چه این‌که آیندۀ کشور، منوط به حمایت از اطفال آینده‌ساز است. نوشتۀ حاضر تلاش کرده با روش تحلیلی و با استفاده از داده‌های کتاب‌خانه‌یی و با روی‌کرد جرم¬شناختی، به این مهم بپردازد. یافته¬های تحقیق نشان می¬دهند که: پیش‌گیری وضعی و اجتماعی در شرایط کنونی افغانستان برای جلوگیری از خشونت علیه اطفال مناسب نیست. روش به‌تر، رفع آسیب‌پذیری اطفالِ در معرض خطر از طریق سازوکارهای آموزشی و نظارتی مندرج در پیش‌‌گیری رشدمدار می¬باشد،‌ که پیش-نهادهای مشخصی را در باب اصلاح متون آموزشی، ایجاد کانون مشاوره در مکتب، آموزش اولیا و مربیان، برگزاری برنامۀ حلقه¬های خانواده‌گی، تأسیس کلینیک حقوقی اطفال، ایجاد مرکز آمار و گزارش خشونت علیه اطفال و ... ارائه می¬کند. این موارد می-تواند راه¬های مؤثری برای تأمین مصونیت اطفال به‌حساب آیند
بررسی رابطۀ کیفیت زنده‌گیِ کاری و عمل‌کرد شغلی با نقش تعدیل‌گر نشاط سازمانی در پوهنتون‌های غالبِ هرات و کابل
Authors:   آمر مالی پوهنتون غالب هرات، هرات، افغانستان, مؤمنی اسلام‌الدین , انور محمد‌عابد
Published: June 2023

کیفیت زنده‌گیِ کاری، تأثیر مهمی روی عمل‌کرد شغلی کارکنان دارد. توجه لازم در این بخش توسط سازمان‌ها، عمل‌کرد شغلی کارکنان را بهبود می‌بخشد و تعالی سازمان را به دنبال دارد؛ هم‌چنان نشاط سازمانی در به‌وجود‌آوردن کیفیت زنده‌گی کاریِ مطلوب در سازمان نقش اساسی دارد و باعث بهبود عمل‌کرد شغلی می‌گردد. این تحقیق با هدف یافتنِ پاسخ به این پرسش که: آیا نشاط سازمانی در دانش‌گاه‌های غالبِ هرات و کابل وجود دارد یا خیر؛ و این مسأله روی کیفیت زنده‌گی کاری و عمل‌کرد کارکنانِ این دو دانش‌گاه، چه‌گونه است؟ شکل گرفته است. تحقیق ازنظر هدف کاربردی و ازنظر ماهیت و روش، از نوع توصیفی- هم‌بسته‌گی بوده‌ است. جامعة آماری این تحقیق را کارمندان دانش‌گاه‌های غالبِ هرات و کابل، که تعداد آن‌ها 350 تن بودند، با استفاده از روش نمونه‌گیری تصادفیِ ساده و بر اساس جدول مورگان، 183‌ نفر نمونه تعیین شدند. به‌منظور گردآوری اطلاعات از دو روش کتاب‌خانه‌یی و میدانی استفاده شد. ابزار تحقیق شامل پرسش‌نامة عمل‌کرد شغلی پاترسون (1992)، پرسش‌نامة نشاط سازمانی کرولف (2007) و پرسش‌نامة کیفیت زنده‌گیِ کاری استون (1998) بود. نتایج نشان داد که نشاط سازمانی موجود در دانش‌گاه‌های غالبِ هرات و کابل، کیفیت زنده‌گی کاری و عمل‌کرد شغلی کارکنانِ این دو نهاد را افزایش داده است
تقابل عقل و عشق در شعر حیدری وجودی
Authors:   دانش‌جوی دکتری زبان و ادبیات فارسی، پوهنتون علّامه طباطبائی، تهران، ایران, رادپور فدامحمد , بشیری دکتر محمود ,   دانش‌یارِ پوهنځی زبان و ادبیات فارسی، پوهنتون علّامه طباطبائی، تهران، ایران, مستعلی پارسا دکتر غلامرضا
Published: June 2023

حیدری وجودی، یکی از بزرگ‌ترین شاعرانِ عارفِ معاصر افغانستان است؛ دیوان شعر او ارزش‌مندترین اثر عرفانی شمرده می¬شود، که در تمام قالب¬های شعری (به‌استثنای قالب معاصر) سروده شده¬ و در حوزۀ عرفان جای‌گاه مهم و برجسته را احراز نموده است. یکی از مسائل بنیادی در عرفان، بحث تقابل عقل و عشق است؛ بنابراین، نیاز است که این موضوع مهم در شعر او موردبررسی قرار گیرد. هدف کلی این تحقیق دریافت پاسخ به این پرسش بوده است که: دیدگاه حیدری وجودی راجع به عقل و عشق چیست؟ این تحقیق براساس هدف، بنیادی، براساس داده‌های کیفی، و براساس روش، تحلیلی-انتقادی است. یافته¬های تحقیق نشان می¬دهند که: «تقابل عقل و عشق» در شعر وجودی واضح و روشن است. وی عقل را به دو دسته: جزئی و عقل ایمانی (عشق) دسته‌بندی نموده و به این باوراست که عقل جزوی تَوَهُم‌آور است، نمی¬تواند سرّ حق را بداند؛ ازاین‌رو، شناخت حقیقت جزء با عقل ایمانی (عشق) امکان¬پذیر نیست؛ هم‌چنان به این باوراست که با قیاس و استدلال درک حقیقت امکان¬پذیر نیست؛ زیرا سرچشمۀ استدلال عقل است و عقل متأثر از پیرامون خود می¬شود
تصور هرات‌نشینان از پوهنتون غالب
Authors:   عضو هیئت‌علمی پوهنځی اقتصاد، پوهنتون غالب، هرات، افغانستان, گنجی فیروز احمد , امیری علی احمد ,   عضو هیئت‌علمی پوهنځی اقتصاد، پوهنتون غالب، هرات، افغانستان
Published: June 2023

امروزه پوهنتون مظهر تحول و نوآوري محسوب مي‌شود و تأثيرات جدي و قابل‌تأملي بر جامعه مي‌گذارد؛ هم‌چنان‌كه خود بسيار تأثير مي‌پذيرد. درواقع پوهنتون، منزوي از جامعه نيست و در حقیقت بسياري از مسائل آن انعكاسي از دنياي در‌حال دگرگون ما مي‌باشد. پوهنتون‌ها به‌عنوان شريانات اصلي گسترش علم و فرهنـگ در جامعه، هم‌واره از ارزش و احترام خاصي برخوردار بوده‌اند. هم انسان‌ساز می‌باشند و هم فرهنگ‌آفرين؛ به‌این‌ترتیب، برحسب ضرورت، در این تحقیق تلاش گردید تا تصور هرات‌نشینان (جامعة هدف: کارفرمایان) از پوهنتون غالب مشخص گردد. اشتراک‌کننده‌گان تحقیق، شهروندان شهر هرات بوده‌اند و براساس نمونه‌گیری احتمالیِ تصادفی ساده، جمعیت نمونه‌یی که حاصل فرمول شوماخر و لومکس به تعداد 320 نفر بوده، با استفاده از پرسش‌نامه تحت مطالعه قرار گرفته‌اند. اطلاعاتِ به‌دست‌آمده نیز با استفاده از نرم‌افزار SPSS24 و Smart PLs 30 مورد تحلیل قرار گرفت، که نتایج حاکی از آن‌است که در بین کارفرمایان ارزش‌های پیوندی پوهنتون و جامعه با ضریب تأثیر 0.908 بیش‌ترین اهمیت و ارزش‌های مسؤولیت‌پذیری اجتماعی با ضریب تأثیر 0.578 پایین‌ترین درجۀ اهمیت را از آن خود نموده است
کرامت انسانی به‌عنوان مبنای حقوق فرد مظنون در نظام حقوق جزای افغانستان و ایران
Authors:   استاد دیپارتمنت حقوق خصوصی و حقوق جزا، پوهنځی حقوق و علوم سیاسی،  پوهنتون بلخ، بلخ، افغانستان, رضایی پوهنمل دکتر ذاکرحسین
Published: June 2023

کرامت انسانی در قلم‌رو حقوق کیفری از جای‌گاه ویژه‌یی برخوردار است؛ زیرا کرامت انسانی بسیاری از حقوق انسانی را اساس‌گذاری می¬کند. امروزه تعریف دقیق و چیستی آن مشخص نیست. ذاتی و قراردادی‌بودن کرامت انسانی جای بحث دارد. حقوق افغانستان و ایران معیارهای متفاوتی را برای فرد مظنون تعریف کرده است. تبیین چیستی کرامت انسانی و رفع نواقص قوانین جزایی هر دو کشور اسلامی، استفاده از مزیت‌های قوانین یک‌دیگر و کاربردی‌ساختن قوانین کیفری هر دو کشور از جمله اهمیت اساسی این پژوهش بوده است. اهداف اساسی این پژوهش این بوده است که به این پرسش‌ها پاسخ بگوید: تعریف واژة مبنا‌ در برابر اصل، منبع و قاعده چیست؟ تعریف مشخص کرامت انسانی چیست؟ کرامت انسانی از‌جمله حقوق ذاتی است یا قراردادی؟ انواع کرامت انسانی کدام‌هایند؟ روش تحقیق، تحلیلی – مقایسه‌وی بوده و ازطریق فیش‌برداری، اطلاعات جمع‌آوری گردیده است. دامنة این پژوهش را تعریف، دسته‌بندی و حقوق ناشی از کرامت انسانی برای فرد مظنون در حقوق افغانستان و ایران، تشکیل داده است. یافته‌های این تحقیق بیان‌گر این هستند: ملاصدرا، کرامت انسانی را یک حق طبیعی می¬داند. علما دسته‌بندی‌های متفاوتی از کرامت انسانی ارائه کرده ‌اند. حقوق ایران و افغانستان اصل را بر کرامت انسانی نهاده و حقوق ناشی از آن را تا حدودی در قوانین شکلی کیفری خود رعایت نموده و ضمانت اجرای مدنی و کیفری را برای ناقضان آن مقرر کرده است
Demanding Apology, Demanding Forgiveness
Authors: Luttrell Johanna C. ,   Philosophy Documentation Center
Published: June 2023

American media is very quick to ask victims of anti-Black violence if they forgive their victimizers. The media’s nearly reflexive framing is a symptom of the broader, cultural demand that Black victims grant forgiveness for racist violence. Reading Juliet Hooker and Myisha Cherry, this paper links the current preponderance of such demand for forgiveness to a demand for apology in America’s lynching tradition. Drawing from Sonya Renee Taylor, Ida B. Wells, and Frederick Douglass, I give a history to both kinds of normative demands and show how, though they appear as seem­ing contraries, demands for forgiveness and apology function together as methods of anti-Black violence. I then draw from work in transformative justice to differentiate the perspectives of asking, giving, and demanding forgiveness. When understood through the perspective of victims, a certain kind of embodied forgiveness can have liberatory potential. However, observers’ demands for forgiveness too often function as a method of racial oppression.
Dental Turizm Kapsamında Önde Gelen Ülkelerin Whatclinic ile incelenmesi; Türkiye, Meksika, Macaristan ve Hindistan Örneği
Authors: AYDIN Armağan , ISIK Ceyda
Published: June 2023

Dental turizm sağlık turizmi içerisinde yer alan döviz kazandırıcı hizmetlerden birisidir. Dünya’da dental turizm hizmetleri ile Türkiye, Macaristan, Meksika ve Hindistan öne çıkan ülkeler arasındadır. Çalışmada nitel araştırma yöntemlerinden gömülü teori tercih edilmiştir. Veri kaynağı olarak whatclinic platformundaki Türkiye, Macaristan, Meksika ve Hindistan özelinde olan yorumlar kullanılmış ve ülkelerin güncel durumu analiz edilmiştir.

Whatclinic’ te bulunan otuz ve üzeri yorum alan 42 klinik incelenerek 2531 yorum pyton programı ile excel dosyası haline getirildikten sonra excel makro ile alt kodlar oluşturularak veriler kategorilere ayrıştırılmıştır. Bu veriler kategorileştirildikten sonra R studio ile grafikleştirilmiştir. Elde edilen bulgulara göre en fazla tercih edilen tedaviler 2 ve üzeri kombine işlemlerden oluşan tedavileri içerirken pedodonti bölümünün ise sadece diaspora turizmi kapsamında tercih edilen bir branş olduğu görünmektedir. Çalışmanın önemli bir katkısı olarak diaspora turizminin dental turizm talebinin oluşmasında ciddi etkisi olduğu çalışmada elde edilen diğer bir bulgudur.

Sonuç olarak bulgular ışığında dental turizm kapsamında yapılan pazar çeşitlendirme faaliyetlerinde branşlara yönelik özelleştirilmiş stratejilerin tercih edilmesinin önemli olabileceği, hedef kitle olarak ise diaspora turistlerinin seçilebileceği düşünülmektedir.
GÜMÜŞHANE İLİNDE GASTRONOMİK BİR DEĞER OLARAK KUŞBURNU ÜZERİNE BİR DEĞERLENDİRME
Authors: AKYÜREK Suat
Published: June 2023

Yabani meyveler, doğada kendiliğinden yetişen ve genellikle içeriğinde sağlığa zararlı olabilecek herhangi bir bileşen bulundurmadığı düşünülen bitkilerdir. Geniş dağlık ve ormanlık alanlara sahip olan Gümüşhane ilinde birçok türde yabani meyve yetişmektedir. Kuşburnu, yaban mersini, böğürtlen, ahududu, dağ çileği, ahlat, yabani ekşi elma ve alıç gibi meyveler Gümüşhane ilinde doğada kendiliğinden yetişen meyvelerdir. Kuşburnu bu yabani meyveler arasında en yaygın ve en fazla kullanım alanına sahip meyvedir. Çalışma, ilde yaygın olarak yetişen bitkinin kullanım alanları, özellikle kuşburnu bitkisinin gastronomik değeri ile bitkinin il ekonomisindeki yeri ve öneminin ortaya konulması amacıyla hazırlanmıştır. İlgili alanyazın tarandığında, kuşburnu bitkisinin çeşitli kullanım alanlarının bulunduğu ve sağlık açısından değerli bir bitki olduğu görülmektedir. Bununla beraber, bitkinin zengin bir gastronomik değere sahip olduğu, gerek tek başına gerekse destekleyici bir gastronomi ürünü olarak birçok ürüne entegre edilerek kullanıldığı anlaşılmaktadır. Gümüşhane ilinde bolca yetişen kuşburnu bitkisinin etkin bir şekilde değerlendirilmesi durumunda, gelecek yıllarda il ekonomisine daha fazla katkı sunabileceği öngörülmektedir. Özellikle kuşburnunun gastronomik bir ürün olarak kullanım alanları çeşitlendirilir ve katma değeri yüksek ürünlere dönüştürülebilirse, başta Gümüşhane mutfağı olmak üzere ülke mutfağına önemli katkılar sağlayabilir.
TOPLUM TEMELLİ TURİZM VE YEREL YÖNETİMLER
Authors: SAYIN Çiğdem
Published: June 2023

Turizm özellikle gelişmekte olan ülkelerin ekonomik kalkınmasında öncü girişimlerden biri olarak değerlendirilmektedir. Turizm hareketleri ile yerel toplumda ve yerel çevrede olumlu ya da olumsuz bazı değişiklikler gerçekleştiği ve kaynakların gelecek nesillerde de kullanımı için sürdürülebilir turizm ilkeleri geliştirildiği görülmektedir. Sürdürülebilir turizmin gerçekleştirilebilmesi için turizmde en önemli paydaşlardan biri olan yerel halkın, turizm süreçlerine başından sonuna kadar katılımı son dönemde toplum temelli turizm anlayışlarını ortaya çıkarmıştır. Toplum temelli turizmde katılım yerel halkın turizmi planlaması, yönetmesi ve getirilerinden adil yararlanması vb. şekillerde gerçekleşir. Toplum temelli turizm yaklaşımı ile yerel kaynakların ve kültürel değerlerin korunması, ekonomik kalkınma, toplumsal refah gibi faydalar gözlenmektedir. Yerel yönetimler yerel halka yakın olma özelliği sayesinde turizmin en önemli paydaşlarından biri olarak görülmektedir. Bu çalışmada, toplum temelli turizm ve yerel yönetimlerin turizm üzerindeki rolünün ve aralarındaki ilişkinin literatürdeki güncel uygulamalar ekseninde teorik olarak incelenmesi amaçlanmıştır. Çalışmada yerel yönetimlerin turizm faaliyetlerinde yerel halkı ve yerel bölgeyi merkeze alan işlev ve sorumluluklarının bulunduğu belirlenmiştir. Sonuç olarak yerel yönetimlerin turizme ya da yerel halka yönelik hizmetlerinin her şekilde turizm hareketlerini ve yerel halkı etkileyebileceği, dolayısıyla yerel yönetimlerin toplum temelli turizmin sürdürülebilirliğinde önemli bir aktör olduğu ortaya çıkarılmıştır.
Metodologi Pembacaan Kritis Atas Kajian Orientalis Terhadap Hadis
Authors: Safitri Diah , Marna Syamsul Mawardi , Amin Ahmad Syaifuddin
Published: June 2023

Studi orientalis terhadap hadits dinilai bias akan kepentingan-kepentingan tertentu, namun perspektif mereka sebagai outsider juga berpotensi objektif karena tidak terikat dengan dogma-dogma yang mengikat insiders. Untuk itu diperlukan pembacaan kritis dalam mengkaji hasil studi orientalis terhadap hadits. Artikel ini mendisuksikan tentang metode pembacaan kritis yang dilakukan oleh M. Muṣṭafa Azami, salah satu sarjana muslim yang konsentrasi di bidang kajian hadits dan orientalisme dalam mengkaji karya para orientalis. Merujuk pada karya Azami, Studies in Early Hadith Literature dan dengan menggunakan metode deskriptif-analitis, peneliti mengkaji letak kritik Azami terhadap para orientalis dan perangkat ilmiah apa saja yang dia gunakan dalam membantah tesis orientalis yang bertentangan dengan pendapatnya. Peneliti menyimpulkan bahwa tujuh ketidaktepatan yang dilakukan orientalis saat mengkaji hadits dalam pembacaan Azami adalah ketidaktepatan dalam menentukan objek yang dikaji, invaliditas data, pemaknaan kata yang menyelisihi sejarah, penggunaan metodologi lama dengan cara yang tidak sesuai, klaim individu yang tidak tepat,  analisis dan tesis yang kurang tepat serta distorsi sejarah baik secara sengaja maupun tidak. Untuk membantah tesis yang dinilai tidak tepat, Azami menyusun sebuah konstruk metodologi kritik dengan lima perangkat utama yaitu argumentasi logis, data filologis, intertektualitas, referensi historis dan menggunakan teori hadits klasik.
The Model Of Quality Management In Strengthening Islamic Higher Education
Authors: Azhar Imam
Published: June 2023

One path of continous improvement in education is by implementing total quality management, which can provide any educational institution with 3 set of practical tools for meeting and exceeding present and future customers needs, wants and expectation. This article is aimed to explore the modern concept about an education which is regarded as service industry. As service industry, educational institution should pay any attention and focus on customers’ needs, wants and expectations that is students themselves and their prospective jobs. In relevant with this, there should be specific model of management which can be implemented continuously, that is Toral Quality Management (TQM). This article is written is based on the library research. The finding shows as follows:, firstly, the implementation concept of TQM in higher education will be successful if it is supported by quality leadership; secondly, teamworks; thirdly, involving and empowering the employees at all levels of institution, such as; decision making and problem solving; fortly, there must be a strategic planning as the engine of quality improvement to guide the running of institution in realizing the customers satisfaction; lastly, there must be good and visoned management as the main factor of quality improvement process and forming an effective team work for quality.
ANALYSIS OF REGIONAL REVENUE AND EXPENDITURE BUDGET FOR KEDIRI REGENCY DURING THE COVID-19 PANDEMIC
Authors: Anik Kurnia Ningsih
Published: June 2023

The existence of the Covid-19 pandemic has had an impact on all economic sectors including the financial performance of local governments. Regional financial analysis is a tool that can be used as a benchmark to assess the extent to which local government performance is managing its finances. Regional ability to manage finances is described in the form of APBD which directly or indirectly reflects the ability of local governments to finance the implementation of governmental tasks, development and community social services. The purpose of this study was to determine the financial management performance of the Regional Government of Kediri Regency based on the analysis of financial ratios in the Kediri Regency APBD. This research is a data series research, namely the Realization of APBD data for 2020 to 2022 in Kediri Regency. The analysis used is normative juristic with a descriptive approach case study method. The analysis tools used are tax ratio, per capita tax, regional fiscal space, regional dependency ratio, ratio of personnel expenditure to total regional expenditure, ratio of capital expenditure to total regional expenditure, ratio of capital expenditure to population, ratio of financial aids expenditure to total regional expenditure, idle funds, growth ratio, effectiveness ratio, and efficiency ratio. From the results of the analysis it is known that the majority of APBD performance during the Covid-19 pandemic had fluctuations.
Meningkatkan Pemahaman Siswa dalam Menyelesaikan Soal Cerita tentang Denah Berskala dengan Metode Tutor Sebaya di Kelas V SDN 34/I Teratai
Authors: Destrinelli Destrinelli , Susanto Agustian , Nofriani Endang , Nabila Nabila , Pratiwi Novia Anggun
Published: June 2023

Education is an important factor in the development of a country. One of the goals of education is to develop students' intellectual abilities and understanding in various fields. In the process of learning mathematics, students' understanding of solving word problems is very important. Word problems provide a real context for students in applying mathematical concepts to everyday life. The purpose of this study was to measure the level of students' understanding in solving word problems about scale plans in Grade V SD. The research was conducted at SDN 34/I Teratai, Muara Bulian District, Batang Hari District. When the research was carried out in the odd semester of the 2022/2023 school year. This research was used in Mathematics Class V semester 1 with the material for solving story problems about Scaled Plans. This research cycle consists of planning, action, observation, and reflection which is done repeatedly until the achievement indicators for this CAR can be achieved. As subjects in this classroom action research were students of Class V SD 34/I Teratai. The number of students who were used as research subjects was 23 people, consisting of 10 men and 13 women. The object of this study was the application of the Peer Tutor Method. Data collection techniques are observation, tests, interviews and documentation. This research was carried out in cycles with each cycle consisting of four components, namely: planning, action and observation, and reflection. After the cycle has been implemented, especially after reflection, it is then followed by re-planning which is carried out in the form of a separate cycle.
Computed Tomography Based Evaluation of the Anterior Group of the Paranasal Sinuses
Authors: Yaprak Fulya , Çoban İstemihan , Sarıoğlu Orkun , Özer Mehmet Asım , Govsa Figen
Published: June 2023

Objective: The study aims to ascertain the prevalence of paranasal sinus variations among healthy adults in the Turkish population, as well as to analyze the symmetry of these variations.
Methods: The CTIs of 200 adult patients who did not have any trauma, carcinoma, tumor, surgery, or a condition that could affect the paranasal anatomy, such as chronic rhinosinusitis, were included. The prevalences of the Agger nasi cell (ANC), supraorbital ethmoid cell (SOEC), Haller's cell (HC), middle turbinate pneumatization, and frontal sinus (FS) agenesis variations in the adult Turkish population were revealed.
Results: Bilateral SOECs were found 38.5% of 200 patients, and at least 53% of patients had SOECs on one side. In 21.5% of instances, LCs were observed on both sides; in 35% of instances, they were observed on at least one side. ANCs were observed bilaterally in 68.5% of the total, the rate of patients with ANC on at least one side was 84.5%. The rate of bilaterality of the Haller cell (HC) was 24%, it was observed at least one side in 43% of the cases. Bilateral concha bullosa (CB) were observed in 19% while CB variation on at least one side was 42%. Bilateral absence of the FS was found to be 8.5%, and unilateral absence was 2.5%.
Conclusion: The most common paranasal sinus variation was ANC, while the least was FS agenesis. Bilateral inheritance was found to be most prevalent in SOEC. The findings of our study hold significance for interventional procedures involving the paranasal region.
Novel USP9X Mutation in A Lebanese Patient with Delay and Microcephaly: Case Report and Review of Literature
Authors: Ghostine Pierre , Seghaye Marie-Christine , Romanos Bassam , Fattah Mohamad , Mansour Hicham
Published: June 2023

Introduction: USP9X gene is located on the X-chromosome and encodes for an enzyme that regulates important substrates involved in neuronal growth and development. Thus, rare USP9X mutations were identified as directly causative of neurodevelopmental disorders (NDDs) and Intellectual Disability (ID) in homozygous males and more rarely in heterozygous females. In males, USP9X variants have been linked to an X-linked mental retardation syndrome that includes; central nervous system (CNS) abnormalities (white matter disturbances, thin corpus callosum, widened ventricles, and cerebellar defects), global delay with significant alteration of speech, language and behavior, hypotonia, joint hypermobility, digital abnormalities, gastro-intestinal symptoms, visual system defects and dysmorphic facial features. Patient Data: We report the rare case of a 3 years old and 8 months male patient presenting with NDD, ID, speech delay, progressive aggressive behavioral changes and CNS abnormalities (microcephaly, left periventricular lesion). He was found to have a USP9X variant carrying a missense mutation: USP9X, c.1870A>T p.(Met624Leu) on Whole-Exome Sequencing (WES). Discussion: Our patient had most of the important features of the previously described X-linked mental retardation syndrome but some were absent such as dysmorphic features, digital or visual abnormalities and hypotonia. Microcephaly rather than macrocephaly was noted, which could be an additional potential CNS malformation, expanding the spectrum of phenotypic characteristics of the USP9X variants. No associated congenital anomalies were noted that are usually more common in female subjects. Conclusion: This is to our knowledge the first reported case of a USP9X variant in Lebanon. The clinical characteristics matched most of the previously described features in the literature. Microcephaly was a new clinical feature not previously described and could be a new possible phenotypic characteristic of the disease.