bluuebunny/crossref_metadata_2025 huggingface dataset:
Predicting Ground Subsidence Due to Long Term Oil/Gas Production in A Niger Delta Basin, Nigeria: Implications for CO2 EOR and Geosequestration
Authors: Abija Fidelis Ankwo , Abam Tamunoene. K. S.
Published: March 2022

Reservoir pressure depletion with production leading to porosity loss, compaction and surface subsidence are the effect of effective stress changes and the imposition of the overburden stress which was partly supported by the fluids on the rock grain skeleton. Ground subsidence is associated with environmental hazards, failure of operational facilities and damages to infrastructures amounting to huge economic losses. In this studies, subsidence has been assessed using the Geertsma nucleus of strain based on predicted reservoir pressure. Depletion was estimated as percentage pore pressure dissipation and dynamically derived geomechanical and petrophysical rock properties determined. Reservoir porosity vary from 15% – 32%, shale volume from 11.2% - 88%, bulk compressibility range from 2.52 – 2.53 x 10−6 /mPa, and uniaxial compaction coefficient 1.15 – 1.8 x 10−6/mPa. The vertical compaction in a typical reservoir interval with a thickness of 31.0m varies from 0.002mm to 0.05mm at 10% formation pressure depletion, - 0.005mm to 0.27mm at 50% formation pressure drawdown and 0.007 to 0.53mm at 99% production and reservoir pressure dissipation. surface subsidence would range from 0.045mm to 0.35mm at 10% pressure depletion, 0.058mm to 1.8mm at 50% pressure depletion and 0.045mm to -3.47mm at full reservoir pressure drawdown. At a distance of 92.45km from the Niger Delta coastline, subsidence in the oilfield can still spread to the coastline, the deformation causing damages to the environment, operational facilities and infrastructures that amount to huge economic losses to the operators and government. We recommend the use of CO2 in EOR to maximize production, mitigate subsidence through ground rebound and keep carbon securely sequestered.
Female Sexual Function in Different Phenotypes of Polycystic Ovarian Syndrome: A Comparative Cross-sectional Study
Authors: Yarjanli Mahsa , Sadatmahalleh Shahideh Jahanian , Mirzaei Negin , Azarbajani Khadijeh
Published: March 2022

Background: Polycystic ovary syndrome (PCOS) coexisting mood disorders along with a combination of aesthetic manifestations may have a detrimental effect on women's sexual function. Hence, different phenotypes of PCOS have different clinical and biochemical signs and symptoms. The aim of this study was to compare women's sexual function (SF) in different phenotypes of PCOS.Methods: This cross-sectional study was conducted on 364 women who met the Rotterdam diagnostic criteria to compare different PCOS phenotypes (A=95, B=78, C=95, and D=95). All patients were invited to fill out the female sexual function index (FSFI).Results: Significant differences were observed between the different phenotypes in terms of the total score, sexual desire, arousal, lubrication, and satisfaction (P<0.001); however, no significant differences were found between them in the terms of pain (P>0.05) and orgasm (P>0.05). In addition, phenotype B had the lowest mean score of total FSFI (P<0.05).Conclusion: The results indicated that women's SF is significantly different in different PCOS phenotypes. It is concluded that in order to solve the SF problems of women with PCOS, different treatment and care measures should be considered according to the relevant phenotype.
Antibiotic exposure prevents acquisition of beneficial metabolic functions in the preterm infant gut microbiome
Authors: Xu Yanping , Milburn Olivia , Beiersdorfer Traci , Du Lizhong , Akinbi Henry , Haslam David
Published: March 2022

Background: Aberrations in the preterm microbiome following antibiotic therapy have been reported in previous studies. The objective of this study was to probe potential underlying mechanisms between this observation and susceptibility to adverse prematurity-related outcomes. Results: Metagenomic shotgun sequencing was performed on 133 stool and 253 skin samples collected at 1 and 3 weeks of age from 68 infants born at <36 weeks postmenstrual age and birth weight <2000 g. After accounting for gestational age and maternal antibiotics, the distribution of organisms in all samples and the corresponding metabolic pathway abundance were compared between infants exposed to postnatal antibiotics and antibiotics-naïve infants. In antibiotic-naïve infants, gestational and postnatal age imparted similar trajectories on maturation of the microbial community and associated metabolic functional capacity, with postnatal age exerting greater contribution. Antibiotic exposure was associated with reversal in maturation trajectory from the first week to the third week of age (p< 0.001). Butyrate producing genera, including Clostridium and Blautia were significantly more abundant in antibiotic-naïve neonates at 3 weeks postnatal age. Correspondingly, metabolic pathways required for short chain fatty acid synthesis were significantly increased in antibiotic-naïve infants, but not in antibiotic-exposed neonates, at three weeks after birth. Conclusions: Early brief antibiotic exposure markedly disrupts developmental trajectory of the neonatal microbiome and its corresponding functional capacity. Our findings may provide a mechanistic explanation for the known associations between antibiotic use and adverse outcomes in preterm infants.
Profile and Triage Appropriateness of Trauma Patients Triaged Green: A Prospective Cohort Study from a Secondary Care Hospital in India
Authors: Anthony Aroke Anna , Dutta Rohini , Sarang Bhakti , David Siddarth , O'Reilly Gerard , Raykar Nakul , Khajanchi Monty , Attergrim Jonatan , Soni Kapil Dev , Sharma Naveen , Mohan Monali , Gadgil Anita , Roy Nobhojit , Wärnberg Martin Gerdin
Published: March 2022

Introduction: Triage is an important component of in-hospital trauma care for adequate patient management and to avoid overcrowding in emergency departments (ED). Prioritising the evaluation of non-urgent patients may result in the diversion of workforce from patients requiring immediate care. However, not evaluating these patients may result in missed injuries and poor outcomes. We aimed to evaluate the profile of these non-urgent patients triaged ‘green’, as part of a triage-trial in a secondary-care hospital in India and validate this against the Cape Triage Score (CTS).Methods: We analysed data of patients triaged green in a prospective single-centre cohort study between July 2016 to November 2019. Clinicians at this triage-naive ED were introduced to a triage trial who then assigned a triage category to trauma patients, aged 18 years and above, on initial evaluation. Telephonic follow-up was performed for all patients included in the study. Triage appropriateness was retrospectively analysed using the CTS. Results: We included 4135 trauma patients triaged green. The mean age of patients was 32.8 (±13.1) years, 77% males. The median (IQR) length of stay of admitted patients was 3 (13) days. Half the patients had a mild Injury Severity Score (3-8), with the majority of injuries being blunt (98%). Of the patients triaged green, 97% came in as direct arrivals and 94.4% were discharged from the ED after initial evaluation. As per CTS, nearly three-quarters (74%) of patients were undertriaged ‘green’ by the clinicians in a triage-naive ED. Conclusion: ​​ Three-fourths (74%) of the patients triaged green by clinicians in a secondary care hospital in Mumbai were mistriaged when retrospectively analysed using CTS. This highlights the need for implementation and evaluation of trauma triage training for the in-hospital first responders (clinicians, nurses and other paramedical staff) in the EDs.
Thinning Pattern and Light Environment in Peach Tree Canopies Influence Fruit Quality
Authors: Corelli-Grappadelli Luca , Coston D.C.
Published: March 2022

The effects of shoot length, fruit density, thinning patterns, and light levels on crop quality of peach (Prunus persica Batsch.) were investigated. On shoots 50 and 75 cm long, fruits were thinned to produce several distribution patterns, with peaches concentrated in the bottom, middle, or distal portion of the shoot, or uniformly spaced along the shoot at two fruit densities (≈10 or 15 cm between fruit). The lower fruit density on the longer shoots resulted in larger fruits. At the same fruit density, fruits clustered in the distal section of the shoot were smaller, with lower soluble solids concentration (SSC) and a smaller percentage of the exocarp colored red than for the other spacing patterns. Photosynthetically active radiation (PAR) was negatively correlated with the percentage of green exocarp and positively correlated with the percentage of red exocarp. However, the low correlation coefficients (0.45 and 0.50, respectively) indicate that even low light levels can result in substantial red pigment development in peach fruit.
A Tobamovirus Associated with Mosaic and Ringspot Symptoms on Barrenwort (Epimedium sp.)
Authors: Nameth S.T. , Putnam M.L. , Valverde R.A. , Reddick B.B.
Published: March 2022

During Spring and Summer 1989 and 1990, the Maryland Dept. of Agriculture obtained several barrenwort (Epimedium sp. C. Morr. and Decne.) hybrids showing virus-like symptoms, including mosaic, line pattern, and concentric chlorotic ringspot. Viral-associated, double-stranded RNA analysis, electron microscopy, serology, and host reactions indicated the presence of a virus with properties similar to those of the tobamovirus group. Serologically, the virus was closely related to tomato mosaic virus. Attempts to infect barrenwort by mechanical inoculations were unsuccessful. This is the first report of a viral infection of barrenwort.
Growth and Subsequent Yield of Tomatoes following End-of-day Light Treatment of Transplants
Authors: Decoteau Dennis R. , Friend Heather H.
Published: March 2022

The influence of end-of-day (EOD) light treatments of tomato (Lycopersicon esculentum Mill. cv. Mountain Pride) transplants on growth and subsequent fruit production was investigated. In the first experiment, transplants were treated with EOD red (R) and far-red (FR) light for 2 weeks in a controlled environment and then placed in the greenhouse under ambient light conditions from November to March. Before transplanting to the greenhouse, transplants treated with EOD R light were shorter and had less total leaf length than plants that were not treated with EOD light (controls). EOD R light increased the number of flowers on the plants before first harvest but had no effect on subsequent fruit production (as compared to plants treated with EOD FR light or control plants). In the second experiment, cool-white fluorescent lights (a light source high in red wavebands) were used to supplement solar light that transplants received in a nonshaded glasshouse for 1 hour before the end of the natural photoperiod. The fluorescent light reduced transplant height and total leaf length as compared to plants not treated with supplemental light. Supplemental fluorescent light for transplants had no effect on subsequent fruit production in the field. These results suggest that EOD light treatments that affect tomato transplant growth do not affect subsequent fruit production.
Inheritance of Resistance to Black Knot in Plums
Authors: Norton Joseph D. , Boyhan George E.
Published: March 2022

Evaluation of progeny resulting from controlled crosses and selfs of various plum (Prunus salicina and hybrids) cultivars revealed that resistance to black knot Apisporina morbosa (Schw.) is controlled by a single recessive gene (proposed designation bk) in the resistant cultivars studied. `Bruce', `Munson', `Crimson', and `Ozark Premier' were homozygous resistant (bkbk), while `Methley' was susceptible and heterozygous (Bkbk) for the trait.
Inheritance of Corolla Striping and Flower Colors in Salpiglossis sinuata
Authors: Conner Patrick , Erickson H.T.
Published: March 2022

Corolla striping in Salpiglossis sinuata Ruiz et Pav6n is controlled by a recessive gene (st). Yellow pigmentation results from the presence of a recessive gene (y) that, when homozygous, is epistatic to genes involved in anthocyanin production. Blue flower pigmentation is recessive to red, bronze, and lavender. A recessive pigment depressing gene (pd) gives reduced color saturation.
Pendampingan Usaha Kecil dan Menengah Mekarsari Dalam Peningkatan Kualitas Usaha
Authors:   Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Adrian Adrian , Mahendra Arista ,   Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Pranoto Claresta ,   Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Galuh Putri Farahayu ,   Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Gavrila Natasha ,   Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Nathan Wilbert ,   Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Wijanarko Winston ,   Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Ervina Dahlia ,   Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339
Published: March 2022

The rapid development of Micro, Small and Medium Enterprises in Indonesia is one of the reasons the Community Service (PKM) activities are being held by Prasetiya Mulya University. Aside from being a learning facility for students, this activity also aims to help residents of Cianjur, especially in the village of Cipendawa, to improve the quality and develop their business. In this journal, the programs main focus is to help Mekarsari, a business that sells snacks and snacks since 1996. To improve product quality, efficiency, and productivity, the writing team replaced damaged production equipment, changed the layout of the workstation for packaging and storage, installing stickers on product packaging, consignment at food stalls, and providing debriefing for daily freelancers and bookkeeping. The achievements of this activity are a decrease in the number of defects and increased productivity in the production process, increasing efficiency in the packaging process, adding distribution channels, giving identity to products by giving stickers, and business’ owner being able to take notes of cash flow neatly and systematically.
PENGARUH ADVERSITY QUOTIENT TERHADAP KEBERHASILAN USAHA PUSAT INDUSTRI KECIL MEDAN DENAI
Authors:   Fakultas Ekonomi & Bisnis, Universitas Sumatera Utara, Medan, Indonesia, Hutagalung Bongsu , Hutagalung Arif Qaedi ,   Fakultas Ekonomi & Bisnis, Universitas Sumatera Utara, Medan, Indonesia
Published: March 2022

This research was aimed to analyze the effect of control, ownership, reach, and endurance as a variable dimension of adversity quotient to the business success in Medan Denai. This type of research explanatory associative research. Based on the results of data processing with multiple linear regression analysis methods, the results of this study indicate that the influence of adversity quotient variables consisting of dimension control, ownership, reach, & endurance simultaneously positive and significant effect on the business success. Partially dimensional control and endurance positive and significant effect to the business success, meanwhile the ownership dimension and reach partially positive but not significant effect to the business success
Effect of ozone–tea polyphenols as a drinking water disinfection process on antibiotic resistance genes
Authors: Feng Cui-min , Yu Hong-ying , Wang Ting , Li Jing , Sun Li-hua , Tao Xing-cheng
Published: March 2022

In recent years, the wide spread of antibiotic resistance genes (ARGs) has brought tremendous risk to the biological safety of drinking water. With the increasing demand for drinking water quality, ARGs have been regarded as a new pollutant that may cause serious public health problems. A large number of studies have shown that the disinfection process of drinking water treatment plants can remove ARGs. However, the effects of traditional disinfection methods on ARGs have their own disadvantages. Tea polyphenols have attracted more and more researchers’ attention as a green, efficient and non-disinfection by-products disinfectant. The effect of the ozone–tea polyphenols disinfection process on ARGs in filtered effluent of waterworks was analyzed by using metagenomic sequencing. The result shows that the ozone–tea polyphenols disinfection process is suitable for specific raw water containing more tetracycline, sulfonamide, β-lactam, and aminoglycoside resistance genes, and the removal rate of total resistance genes in water is higher than the traditional disinfection process. The effect of the ozone–tea polyphenols disinfection process on ARGs is to reduce the transfer of ARGs by destroying ARGs molecules and inhibiting the proliferation of ARGs host cells. As an assistant disinfectant, tea polyphenols have significance for the ability to remove ARGs during traditional disinfection.
Performance analysis of a half-batch multi-cell three-dimensional electrode reactor for drilling wastewater: COD removal, energy consumption and hydrodynamic characteristic
Authors: Wang Li , Liang Hong , Huang Hong , Wang Qingchun , Yang Youli , Zheng Qiang
Published: March 2022

Although a three-dimensional electrode system (3DES) has made remarkable achievements in improving the property of electrodes and investigating pollutant degradation mechanism, the design of an electrochemical reactor for application in drilling wastewater has not been reported yet. In this study, a novel half-batch multi-cell 3DES reactor was constructed by us to degrade organic compounds from drilling wastewater. The separate effect of electrolysis time, current density, the configuration of granular activated carbon (GAC) electrodes, aeration rate and volumetric recirculation flow on chemical oxygen demand (COD) removal and energy consumption of the half-batch reactor were analyzed, and further optimization via response surface methodology (RSM). Results showed that the optimal operation conditions for the reactor included electrolysis time of 100 min, a current density of 9.2 mA/cm2, GAC electrode vertical configuration, an aeration rate of 2.67 L/min and a volumetric recirculation flow of 100 mL/min. Under these conditions, the maximum percentage COD removal was found to be 97.39% with an energy consumption of 77.89 kWh(kg COD)−1. The residence time distribution (RTD) method was carried out in continuous flow pattern to investigate the hydrodynamic characteristics of the reactor. Results showed that flow rate was the most dominant factor for the flow pattern of the reactor, followed by the aeration rate and current density. The low dispersion number and the percentage of dead volume are 0.214 and 3.87% when the flow rate of 100 mL/min, respectively, which indicates that there is an intermediate flow pattern existing in between plug-flow ideal and complete mixing flow, furthermore, it is close to the plug-flow ideal.
Impact of the second phase of the eastern route of South-to-North water diversion project on distribution of nitrogen and phosphorus in Hongze Lake
Authors: Jiang Zhi , Liu Chang , Wang Shiyan , Li Cunwu , Zou Jiaxiang , Li Budong , Wu Weixiong
Published: March 2022

Nitrogen (N) and phosphorus (P) concentrations are the fundamental factors affecting the nutrient status and productivity of lakes, and extrinsic inputs of N and P primarily cause eutrophication of lakes. In this essay, taking Hongze Lake as the study area, a two-dimensional hydrodynamic and water quality mathematical model of Hongze Lake was constructed, and based on calibration and verification of parameters, numerical simulation was performed on the changes in N and P concentrations in this lake after water transfer. The study results exhibited that before and after project construction, the absolute values of rates of changes in the annual average concentrations of ammonia nitrogen (NH4+-N), total phosphorus (TP), total nitrogen (TN), and permanganate index (CODMn) in Hongze Lake were all lower than 20%, which demonstrates marginal changes in the annual average concentrations. By analyzing the seasonal and spatial distribution characteristics of the concentrations of N, P and other pollutants in the lake area before and after the project operation, it is found that the main reasons that affect the water quality change in the lake area after the project operation are the newly added water transfer volume, water transfer location, and water transfer quality.
Eğitim Fakültelerinde Öğrenim Gören Öğretmen Adaylarının Değer İfadesi Tercihlerinin İncelenmesi
Authors: İPEK Pelin , ÖKMEN Ahmet Şadan
Published: March 2022

Bu araştırmada, MSKÜ Eğitim Fakültesi yaz okulunda öğrenim gören, farklı üniversitelerin eğitim fakültelerinden öğretmen adaylarının değer ifadesi tercihlerinin incelenmesi amaçlanmıştır. Araştırmanın çalışma grubunu MSKÜ Eğitim Fakültesi yaz okulunda öğrenim gören öğretmen adaylarının 168’i kadın (%62.7), 100’ü erkek (%37.3) toplam 268 öğretmen adayı oluşturmaktadır. Öğretmen adaylarının değer ifadesi tercihlerini incelemek amacıyla Dilmaç ve diğerleri (2014) tarafından geliştirilen değerler ölçeği kullanılmıştır. KolmogorovSmirnov testi sonuçlarına göre cinsiyet, büyüdüğü yer, yaş, bölüm, sınıf düzeyi ve medeni durumları p < .05 düzeyinde anlamlı bir farklılık gösterdiği için dağılımların normal olmadığı sonucuna ulaşılmıştır. Verileri analiz etmede betimsel istatistikler, ilişkisiz örneklemler t testi, Mann Whitney U testi, tek yönlü varyans analizi ve Kruskal Wallis H testi tekniklerinden yararlanılmıştır. SPSS 25 istatistiksel analiz programı kullanılmıştır. Araştırma sonucunda öğretmen adaylarının değer ifadesi tercihleri cinsiyetlerine göre anlamlı farklılık gösterdiği; diğer puan ortalamalarının ise anlamlı farklılık göstermediği görülmektedir. Toplumsal Değer için kadınların puan ortalaması (= 84,69), erkeklerin puan ortalamasından (= 81,93) daha yüksektir. Benzer şekilde Entelektüel Değerler için kadınların ortalaması (= 41,63) erkeklerin ortalamasından (= 39,98) daha yüksektir.
Recuperación de tierras en el pueblo zenú. Fortalecimiento del resguardo indígena y etnicidad
Authors: Velandia Díaz Daniel
Published: March 2022

Este libro presenta una dimensión del pueblo zenú: los procesos de la lucha por la tierra que permitieron el fortalecimiento de la etnicidad. Se trata de una revisión de la historia social a través de la realización de trabajo de campo, entrevistas a profundidad y revisión documental. La recuperación de tierras, organizada a partir de la década de los años sesenta del siglo XX, es caracterizada en sus diferentes etapas con el apoyo de relatos y reflexiones de varios líderes indígenas. Dentro del análisis se muestran las transformaciones institucionales en el proceso de consolidación del resguardo y las contradicciones existentes entre las perspectivas indígenas y las de la sociedad nacional. A su vez, el texto presenta la experiencia antropológica de forma detallada, reflexiva y con anotaciones sobre el proceso de recepción social de la investigación. El libro expone una cartografía indicativa de los procesos sociales e históricos, y dialoga con diversas fuentes sobre los desafíos que afrontó el pueblo zenú de cara al reconocimiento de su resguardo. Si bien se trata de una revisión de un proceso localizado de larga duración, el autor conecta la recuperación de tierras de los zenúes con las problemáticas globales de explotación y mercantilización de la tierra.
O falante no romance e o discurso autoritário do fundamentalismo religioso: The Handmaid’s Tale sob lentes dialógicas
Authors: Estevam de Carvalho Pessoa Caroline , Bandeira de Melo Júnior Orison Marden
Published: March 2022

Pensando na interação entre mundo da arte e mundo da vida, The handmaid’s tale (ATWOOD, 1986) nos chama a refletir sobre a criação de uma sociedade totalitária representada na obra. Para a compreensão dessa representação, este trabalho pautou-se na teoria do romance de Bakhtin, em especial nos conceitos de falante do romance e discurso autoritário, bem como no conceito de fundamentalismo, segundo Armstrong, Oz, Sloterdijk e Harari. Dessa forma, este trabalho buscou compreender, no romance, o papel do discurso autoritário da religião fundamentalista na criação e no desenvolvimento de regimes autoritários com base na religião. Foi possível perceber, por meio da análise, que a assimilação natural ou compulsória do discurso autoritário fundamentalista provocou confrontos violentos e possibilitou a entrada de políticas opressoras. O romance, portanto, chama o leitor a refletir sobre o avanço de discursos autoritários com base no discurso religioso fundamentalista em sociedades contemporâneas.
PATRIMÔNIO ARQUITETÔNICO/HISTÓRICO DE SOBRAL
Authors: Barbosa Gomes Mirtes , Pereira de Paula Davis
Published: March 2022

Objetivou-se apresentar as peculiaridades da paisagem urbana sobralense a partir da contribuição oferecida pelo patrimônio arquitetônico, a fim de proporcionar uma melhor compreensão visuoespacial do sítio histórico de inegável predomínio do legado português. Sobral tem sua expressividade econômica e cultural retratada em casarões coloniais, igrejas e praças, vestígio de um período áureo de abastança. Esse trecho representa a parte mais antiga da cidade, apresentando uma arquitetura com estilos diversificados. Na metodologia de pesquisa empregou-se a técnica do QR Code que permitiu apresentar os bens patrimoniais, refletindo sobre as várias dimensões do uso dessa tecnologia digital. Além disso, também foi disponibilizado o site PatriSol com as características, roteirização e potenciais atrativos desse centro histórico, impulsionando o turismo cultural e a valorização das identidades locais.
EVOLUÇÃO DA COBERTURA E USO DA TERRA NAS ÁREAS DE INFLUÊNCIA DIRETA DAS USINAS HIDRELÉTRICAS BATALHA E ITUMBIARA SOB O APORTE DE FONTES SECUNDÁRIAS DE DADOS CARTOGRÁFICOS E CENSITÁRIOS
Authors: Silva Izaias de Souza , Nascimento Diego Tarley Ferreira , Romão Patrícia de Araújo , Sales Maurício Martines , Luz Marta Pereira da
Published: March 2022

No contexto de desenvolver uma proposta de mapeamento da cobertura e uso da terra em escala progressiva de detalhe para o entorno de Usinas Hidrelétricas (UHE), tem-se por objetivo, no presente trabalho, avaliar o emprego de dados secundários da dinâmica da cobertura e uso das terras do Projeto Mapbiomas, além de dados socioeconômicos e agropecuários oriundos da Plataforma SIDRA IBGE, em ambos casos, retratando o recorte temporal de 1985 a 2020, e tendo como estudo de caso as áreas de influência direta das UHEs de Batalha e Itumbiara. Evidencia-se a dinâmica da cobertura e uso das terras junto à UHE de Batalha, com redução das áreas ocupadas por pastagens e incremento das áreas agrícolas, e sucessiva supressão da cobertura vegetal. Para o caso da UHE de Itumbiara, percebe-se uso das terras já consolidados, com predomínio de pastagens.
Good and Justice in the Context of Environmental Ethics
Authors: Mihailov Nikolai , Sakelarieva Lidia
Published: March 2022

The article is an attempt to review some basic ethical concepts in their historical and substantive development, within the context of the environment and environmental knowledge. It also tries to answer the question whether there is a difference between traditional and environmental ethics. The comparative-historical method is used, which considers some classical ethical concepts and their interpretations related to the environment. The concepts of classical and modern scientists are also analyzed. The authors consider whether these concepts should be supplemented with new content in this area or should be reformulated in terms of moral relevance not only for the human community, but also for all non-human inhabitants of the environment.  The article explores issues about the origin of morality, as well as some ideas about the moral status of attitudes among primates. More important conclusions are that ethics and environmental knowledge must be developed in cooperation in order to explain and form moral consciousness, a new type of ethos that does not allow indifference to the environment in human interaction with it, and that moral considerations should contain not only prescriptions for due human behavior in human society, but also obligations to non-human inhabitants of nature or to the environment.
A Review On Huntington Protein: Insight Into Protein Aggregation and Therapeutic Interventions
Authors: Srinivasan Ekambaram , Ram Vavish , Rajasekaran Ramalingam
Published: March 2022

Huntington's disease (HD) is a distressing, innate neurodegenerative disease that descends from CAG repeat expansion in the huntingtin gene causing behavioral changes, motor dysfunction, and dementia in children and adults. Mutation in huntingtin (HTT) protein has been suggested to cause neuron loss in the cortex and striatum through various mechanisms, including abnormal regulation of transcription, proteasomal dysfunction, posttranslational modification, and other events regulating toxicity. Pathogenesis of HD involves cleavage of the huntingtin protein followed by the neuronal accumulation of its aggregated form. Several research groups made possible efforts to reduce huntingtin gene expression, protein accumulation, and protein aggregation using inhibitors and molecular chaperones as developing drugs against HD. Herein, we review the mechanism proposed towards the formation of HTT protein aggregation and the impact of therapeutic strategies for the treatment of HD.
Contribution of STIM-Activated TRPC-ORAI Channels in Pulmonary
Hypertension Induced by Chronic Sustained and Intermittent Hypoxia
Authors: Castillo-Galán Sebastián , Arenas Germán A. , Iturriaga Rodrigo
Published: March 2022

Sustained and intermittent hypoxia produce vasoconstriction, arterial remodeling, and hypertension
in the lung. Stromal interaction molecule (STIM)-activated transient receptor potential channels
(TRPC) and calcium release-activated calcium channel protein (ORAI) channels (STOC) play key roles
in the progression of pulmonary hypertension in pre-clinical models of animals subjected to sustained
and intermittent hypoxia. The available evidence supports the theory that oxidative stress and hypoxic
inducible factors upregulate and activate STIM-activated TRPC-ORAI Ca2+ channels, contributing to
the pulmonary remodeling and hypertension induced by sustained hypoxia. However, less is known
about the effects of oxidative stress and hypoxic inducible factors on the modulation of STIM-activated
TRPC-ORAI channels following chronic intermittent hypoxia. In this review, we examined the emerging
evidence supporting the theory that oxidative stress and hypoxic inducible factors induced by intermittent
hypoxia upregulate and activate STIM-activated TRPC-ORAI Ca2+ channels. In addition, we
used bioinformatics tools to search public databases for the genes involved in the upregulation of STIMactivated
TRPC-ORAI Ca2+ channels and compare the differential gene expression and biological processes
induced by intermittent and sustained hypoxia in lung cells.
Syncope Prediction Scores in the Emergency Department
Authors: Liu Tong , Liang Yan , Li Xiulian , Tse Gary , King Emma , Roever Leonardo , Li Guangping
Published: March 2022

Syncope is a common clinical presentation defined as a transient loss of consciousness
(TLOC) due to cerebral hypoperfusion, characterized by a rapid onset, short duration, and spontaneous
complete recovery. Different clinical decision rules (CDRs) and risk stratification scores
have been developed to predict short- and long-term risks for adverse outcomes after syncope. The
central theme of these prediction systems is consistent with the ESC syncope guidelines. Initial assessment
according to the ESC guideline is essential until an optimal and well-validated risk score
is available. The focus should be accurate risk stratification to allow prevention of adverse outcomes
and optimize the use of limited healthcare resources. In this review article, we summarize
and critically appraise the evidence regarding the CDRs for patients presenting with syncope.
Factors Associated with Women Fertility in Bangladesh: Application on
Count Regression Models
Authors: Haq Iqramul , Hossain Md. Ismail , Saleheen Ahmed Abdus Saleh , Nayan Md. Iqbal Hossain , Afrin Tanjina , Talukder Ashis
Published: March 2022

Background:

The current total fertility rate in Bangladesh is now 2.3 births per woman,
which is still above the replacement level of 2.1.

Objective:

The main objective of this study was to identify potential factors associated with fertility
transition in Bangladesh.

Methods:

This study applied several regression models to find the best-fitted model to determine
factors associated with the number of children ever-born in Bangladesh and utilize data from the
2019 Bangladesh Multiple Indicator Cluster Survey.

Results:

Based on the principles of the AIC, BIC, and Vuong tests, the best-fit model was the Hurdle-
Poisson regression model compared to other models. Findings based on the Hurdle Poisson regression
result revealed that the number of children increases with the increase of women’s age, but
the number of children declines if the education status of women as well as their delayed marriage
increases. Women who had secondary or higher education were less likely to have children than illiterate
women. Similarly, division, residential area, wealth index, women’s functional difficulties,
prenatal care, and migration have significantly influenced the number of children ever born.

Conclusion:

Based on the findings, the study suggests that fertility can be decreased by improving
female education, minimizing early marriage, and eliminating poverty for all ever-married women
who were particularly live in rural areas of the Chattogram and Sylhet divisions in Bangladesh.
Such steps would be the largest contribution to a future reduction in fertility rates in Bangladesh.
FDG-PET/CT Assessment of the Cerebral Protective Effects of Hydrogen
in Rabbits with Cardiac Arrest
Authors: Huang Guoqing , Li Xiangmin , Tang Yongxiang , Yao Zhengbin , Hu Shuo , Zhou Hui , Mo Xiaoye , She Changshou , Lu Xiaoqin
Published: March 2022

Background:

Anatomical imaging methods and histological examinations have limited
clinical value for early monitoring of brain function damage after cardiac arrest (CA) in vivo.

Objective:

We aimed to assess the cerebral protective effects of hydrogen in rabbits with CA by using
fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT).

Methods:

Male rabbits were divided into the hydrogen-treated (n=6), control (n=6), and sham (n=3)
groups. Maximum standardized uptake values (SUVmax) were measured by FDG-PET/CT at baseline
and post-resuscitation. Blood Ubiquitin C-terminal hydrolase-L1 (UCH-L1) and neuron-specific enolase
(NSE) were measured before and after the operation. After surgical euthanasia, brain tissues were
extracted for Nissl staining.

Results:

SUVmax values first decreased at 2 and 24 h after resuscitation before rising in the hydrogentreated
and control groups. SUVmax values in the frontal, occipital, and left temporal lobes and in the
whole brain were significantly different between the hydrogen and control groups at 2 and 24 h postresuscitation
(P<0.05). The neurological deficit scores at 24 and 48 h were lower in the hydrogentreated
group (P<0.05). At 24 h, the serum UCH-L1 and NSE levels were increased in the hydrogen
and control groups (P<0.05), but not in the sham group. At 48 and 72 h post-CA, the plasma UCH-L1
and NSE levels in the hydrogen and control groups gradually decreased. Neuronal damage was smaller
in the hydrogen group compared to the control group at 72 h.

Conclusion:

FDG-PET/CT could be used to monitor early cerebral damage, indicating a novel method
for evaluating the protective effects of hydrogen on the brain after CA.
An Insight of Clinical Evidence of Ayurveda Interventions in the Management
of COVID-19 Patients
Authors: Maideen Naina Mohamed Pakkir , Balasubramanian Rajkapoor , Manavalan Gobinath , Balasubramanian Kumar , Subramanian Nivedhitha , Murugesan Thirumal , Solaimalai Vasanth Kumar
Published: March 2022

Background:

Coronavirus disease 2019 (COVID-19) was caused by the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) and patients with COVID-19 may be treated with
traditional medicine like Ayurveda alone or in combination with standard allopathic treatment, as
Ayurveda is one of the oldest traditional medicinal systems followed by millions around the world.

Methods:

The literature was searched in databases such as LitCOVID, Google Scholar, Science Direct,
EBSCO, Scopus, Web of Science, EMBASE, and reference lists to identify articles relevant to the use
of Ayurvedic medicines in the management of COVID-19.

Results:

Several clinical studies have determined the efficacy of Ayurvedic medicines and formulations
in the management of patients with COVID-19.

Conclusion:

The Ayurvedic medicines and formulations with antiviral, antioxidant, anti-inflammatory,
and immunomodulatory properties could be used along with standard allopathic medicines to assist in
the earlier detection of virus, speedy recovery of patients with COVID-19, faster discharge from hospitals,
and the prevention of further deterioration.
Radioprotective Mechanisms of Arbutin: A Systematic Review
Authors: Sadeghinezhad Shima , Khodamoradi Ehsan , Diojan Loghman , Taeb Shahram , Najafi Masoud
Published: March 2022

Purpose:

Efforts to produce radioprotective agents of high potential are appropriate
strategies for overcoming possible IR toxicity in organisms. The present research aims to evaluate
the signaling pathways and mechanisms through which arbutin exerts radioprotective effects on
organisms.

Methods:

The databases of PubMed, Web of Sciences, Google Scholar, and Scopus were searched
to find studies that reported radioprotective effects for arbutin. Besides, the data were searched
within the time period from 2010 to 2020.

Result:

Five research articles met our criteria, which were included in the analysis based on their
relevance to the topic. The present systematic review provides conclusions about various mechanisms
and pathways through which arbutin induces radioprotection.

Conclusions:

Based on the relevant studies, various mechanisms can be proposed for inducing
radioprotective effects by arbutin, including inhibition of oxidative stress, apoptosis, and inflammation.
Nutraceutical Potentials of Azanza garckeana (Snot Apple): A Review
Authors: Kazeem Mutiu Idowu , Adenowo Abiola Fatimah , Salisu Fausat Titilola , Akinsanya Mushafau Adewale
Published: March 2022

Background:

Nutraceuticals are products derived from natural sources and are used as therapeutic agents for the management of various health disorders. Several nutraceuticals have been produced from fruits, including wild edible fruits. Azanza garckeana is an example of wild edible fruit belonging to the Malvaceae family. It is a semi-deciduous flowering plant that grows in savan-na-wooded grasslands and open forests. It can be found in tropical Eastern Africa, Southern Africa, and some countries of Western Africa. All parts of the plant are useful for medical and economic purposes. There are various traditional claims on the application of various parts of the plant in the management and treatment of diabetes, infertility, aches and pains, hemorrhage, liver and cardiac diseases, etc.

Objective:

This article presents a review of the plant Azanza garckeana regarding its botanical de-scription, its traditional relevance economically and medically, and its established nutritional as well as pharmacological relevance based on reported in vitro and in vivo experimental investigations.

Conclusion:

Experimental reports on the nutritional and pharmacological potentials of Azanza garckeana are sparse. Therefore, there is a need for extensive research to further establish the plant as a potential candidate for a pharmacological or nutraceutical agent for the management of oxida-tive stress-related diseases and other human health disorders.
Sonification for Everyone Everywhere - Evaluating the WebAudioXML Sonification Toolkit for Browsers
Authors: Lindetorp Hans , Falkenberg Kjetil
Published: March 2022

Creating an effective sonification is a challenging task that requires skills and knowledge on an expertise level in several disciplines. This study contributes with WebAudioXML Sonification Toolkit (WAST) that aims at reaching new groups who have not yet considered themselves to be part of the ICAD community. We have designed, built, and evaluated the toolkit by analysing ten student projects using it and conclude that WAST did meet our expectations and that it lead to students taking a deep approach to learning and successfully contributed to reaching the learning outcomes. The result indicates that WAST is both easy-to-use, highly accessible, extensively flexible and offers possibilities to share the sonification in any device’s web browser simply through a web link, and without installations. We also suggest that a sonification toolkit would become an even more creative environment with virtual instruments and mixing features typically found in Digital Audio Workstations.
Musical Features Modification for Less Intrusive Delivery of Popular Notification Sounds
Authors: Yang Jing , Roth Andreas
Published: March 2022

Less intrusive information delivery has been a popular research topic for auditory displays. While most research has addressed this issue by creating new notification cues such as rendering ambient soundscapes or modifying background music, we present a novel method to gently deliver artificial notification sounds that have been commonly used in digital devices and for popular applications. We propose to play a notification sound by embedding it into the music that a user is listening to, after changing the musical timbre, amplitude, tempo, and octave of the notification to match these features of the music. To implement this concept, we extend a melody extraction algorithm for notification timbre transfer, and we present a pipeline that algorithmically selects a proper time spot and harmoniously embeds the notification into music. To validate our design concept, we present a user study comparing our method with the standard method of playing notification sounds on digital devices. Through an extensive analysis of 96 tasks performed by 32 participants, we demonstrate that our method can deliver notification sounds in a less intrusive but adequately noticeable manner and is preferred by most participants.
Openspace Sonification: Complementing Visualization of the Solar System with Sound
Authors: Elmquist Elias , Ejdbo Malin , Bock Alexander , Rönnberg Niklas
Published: March 2022

Data visualization software is commonly used to explore outer space in a planetarium environment, where the visuals of the software is typically accompanied with a narrator and supplementary background music. By letting sound take a bigger role in these kinds of presentations, a more informative and immersive experience can be achieved. The aim of the present study was to explore how sonification can be used as a complement to the visualization software OpenSpace to convey information about the Solar System, as well as increasing the perceived immersiveness for the audience in a planetarium environment. This was investigated by implementing a sonification that conveyed planetary properties, such as the size and orbital period of a planet, by mapping this data to sonification parameters. With a user-centered approach, the sonification was designed iteratively and evaluated in both an online and planetarium environment. The results of the evaluations show that the participants found the sonification informative and interesting, which suggest that sonification can be beneficially used as a complement to visualization in a planetarium environment.
Fast neutrons irradiation as a way to overcome feline squamous cell carcinoma radioresistance: a pilot study
Authors:   A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (A. Tsyb MRRC), Rodionov M.V. , Koryakin S.N. ,   A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (A. Tsyb MRRC), Saburov V.O. ,   A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (A. Tsyb MRRC), Moiseev A.S. ,   A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (A. Tsyb MRRC), Petrova Yu.V. ,   A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (A. Tsyb MRRC), Shegay P.V. ,   National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (NMRRC), Ivanov S.A. ,   A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (A. Tsyb MRRC), Kaprin A.D. ,   National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (NMRRC)
Published: March 2022

For the study 4 cats with unresectable oral squamous cell carcinoma were treated with combina-tion of neutron and electron radiations. 3 cats had T2b and one had T3b stage. The first phase of treatment was performed with 14 MeV fast neutron beam, fraction dose varied from 1.0 to 1.3 Gy, 3 fractions a week, 3-5 fractions in total; in the second phase the animals were irradiated with 10 MeV electron beam, using same fractionation, fraction dose varied from 4 Gy, up to total dose of 8-36 Gy. In the course of treatment, most cats had partial or complete anorexia, the duration of which did not exceed two days, it was well controlled by antidepressants (mirtazapinum). Visual assessment and computed tomography performed from 13 to 30 days after treatment comple-tion demonstrated showed the significant regression of tumor volume (30-67%) in all cases. 3 out of 4 animals were alive at the time of the study, average follow-up period was 84 days, maximum follow-up period was 160 days. Radiation damage was limited to local alopecia followed by leu-kotrichia.