bluuebunny/crossref_metadata_2025 huggingface dataset:
A useful tool for the safe diagnosis and control of the two main pandemics of the XXI century: COVID-19 and African Swine Fever disease
Authors: Barroso-Arévalo Sandra , Díaz-Frutos Marta , Kosowska Aleksandra , Pérez-Sancho Marta , Domínguez Lucas , Sánchez-Vizcaíno José Manuel
Published: March 2023

The COVID-19 pandemic and the disease triggered by the African Swine Fever virus are currently two of the main problems regarding public and animal health, respectively. Although vaccination seems to be the ideal tool for controlling these diseases, it has several limitations. Therefore, early detection of the pathogen is critical in order to apply preventive and control measures. Real-time PCR is the main technique used for the detection of both viruses, which requires previous processing of the infectious material. If the potentially infected sample is inactivated at the time of sampling, the diagnosis will be accelerated, impacting positively on the diagnosis and control of the disease. Here, we evaluated the inactivation and preservation properties of a new surfactant liquid for non-invasive and environmental sampling of both viruses. Our results demonstrated that the surfactant liquid effectively inactivates SARS-CoV-2 and African Swine Fever virus in only five minutes, and allows for the preservation of the genetic material for long periods even at high temperatures such as 37°C. Hence, this methodology is a safe and useful tool for recovering SARS-CoV-2 and African Swine Fever virus RNA/DNA from different surfaces and skins, which has significant applied relevance in the surveillance of both diseases.
Comparing the structure-function relationship between the visual fields measured with variational Bayes linear regression and SITA standard
Authors: Asaoka Ryo , Murata Hiroshi , Fujino Yuri , Aoki Shuichiro , Hirasawa Kazunori , Shoji Nobuyuki
Published: March 2023

Purpose

We recently constructed an algorithm to measure visual field (VF) using the variational Bayes linear regression (VBLR). This algorithm enabled a faster VF measurement than the Swedish interactive thresholding algorithm (SITA) standard while maintaining the test-retest reproducibility (Murata H, et al. Br J Ophthalmol 2021). The current study aimed to compare the structure-function relationship between the SITA standard and VBLR.

Method

In 78 eyes of 56 patients with primary open-angle glaucoma, VF measurements were conducted using both SITA standard and VBLR VF, as well as spectral-domain optical coherence tomography. The structure-function relationship was investigated between visual sensitivity and circumpapillary retinal nerve fiber layer in the whole VF. This analysis was repeated for each of the 12 sectors (30 degrees). The strength of the structure-function relationship was evaluated using the second-order bias-corrected Akaike Information Criterion (AICc) index.

Result

In the whole VF, AICc values of SITA standard and VBLR were 601.6 and 597.3, respectively. The relative likelihood that VBLR had a better structure-function relationship than the SITA standard was 88.2% (when the entire field was averaged) or 99.9% (when all test points were analyzed in the pointwise manner). With the sector-wise analysis, SITA standard had a better structure-function relationship than VBLR in 1 sector (Superior sector in the retina), whereas VBLR had a better structure-function relationship than SITA standard in 4 sectors (Supero-Nasal, Infero-Nasal, Inferior, and Infero-Temporal sectors) with >95% relative likelihood.

Conclusion

Although it depends on locations and similar between SITA standard and VBLR-VF, but VBLR-VF had a better structure-function relationship than the SITA standard overall.
Structure and function of Plasmodium actin II in the parasite mosquito stages
Authors: Lopez Andrea J. , Andreadaki Maria , Vahokoski Juha , Deligianni Elena , Calder Lesley J. , Camerini Serena , Freitag Anika , Bergmann Ulrich , Rosenthal Peter B. , Sidén-Kiamos Inga , Kursula Inari
Published: March 2023

Actins are filament-forming, highly-conserved proteins in eukaryotes. They are involved in essential processes in the cytoplasm and also have nuclear functions. Malaria parasites (Plasmodium spp.) have two actin isoforms that differ from each other and from canonical actins in structure and filament-forming properties. Actin I has an essential role in motility and is fairly well characterized. The structure and function of actin II are not as well understood, but mutational analyses have revealed two essential functions in male gametogenesis and in the oocyst. Here, we present expression analysis, high-resolution filament structures, and biochemical characterization of Plasmodium actin II. We confirm expression in male gametocytes and zygotes and show that actin II is associated with the nucleus in both stages in filament-like structures. Unlike actin I, actin II readily forms long filaments in vitro, and near-atomic structures in the presence or absence of jasplakinolide reveal very similar structures. Small but significant differences compared to other actins in the openness and twist, the active site, the D-loop, and the plug region contribute to filament stability. The function of actin II was investigated through mutational analysis, suggesting that long and stable filaments are necessary for male gametogenesis, while a second function in the oocyst stage also requires fine-tuned regulation by methylation of histidine 73. Actin II polymerizes via the classical nucleation-elongation mechanism and has a critical concentration of ~0.1 μM at the steady-state, like actin I and canonical actins. Similarly to actin I, dimers are a stable form of actin II at equilibrium.
Antagonismo de bactérias ácido-láticas contra Staphylococcus aureus produtor de enterotoxina C em queijo tipo Minas Frescal durante a estocagem
Authors: Mariano Emanuelly Gomes Alves , De Souza Marcelo Resende , Duarte Eduardo Robson , Dias Ricardo Souza
Published: March 2023

A avalição dos parâmetros microbiológicos de alimentos representa indícios da qualidade e segurança de suas matrizes, que podem oferecer riscos e causar danos à saúde do consumidor quando os valores observados estão incompatíveis com os critérios apropriados. O leite e seus produtos derivados estão frequentemente relacionados à intoxicação estafilocócica, uma vez que cepas enterotoxigênicas de Staphylococcus spp. é citado como um dos causadores de mastite bovina. Como forma de elucidar alternativas eficazes de impedir o desenvolvimento de S. aureus em matriz láctea, produziram-se queijos, adicionados de combinações de uma cepa padrão S. aureus FRI361 produtora de enterotoxina C, e duas bactérias ácido-láticas (BAL) Lactobacillus plantarum e Lactobacillus rhamnosus isoladas de soro-fermento de queijarias cadastradas da Canastra em Minas Gerais e identificadas proteômicamente pela técnica de MALDI-TOF. Os queijos Minas Frescal, produzidos com cepas de BAL, foram capazes de reduzir a contagem de S. aureus do 1º ao 14º dia após a produção, nos tratamentos que apresentaram pelo menos uma BAL junto do patógeno. A presença de bactérias ácido-láticas mostrou potencial ação inibidora frente ao S. aureus no queijo Minas Frescal, podendo contribuir para a melhoria da qualidade sanitária de queijos frescos.
“Fouling”: revisão sobre a deposição e desestabilização das proteínas lácteas durante o processamento
Authors: De Oliveira Thacila Fernanda , Costa Fabiano Freire
Published: March 2023

O fouling é um fenômeno de deposição de proteínas e/ou minerais que ocorre na superfície de trocadores de calor, no interior de poros de membranas, causando incrustação nesses equipamentos e, como consequência, a deposição no fundo de caixas de leite UHT. Esta incrustação pode ser do tipo A ou B, dependendo se seu constituinte majoritário for proteínas ou minerais, respectivamente. Diversos fatores são inerentes ao fouling: Elevadas temperaturas utilizadas no processamento do leite, como a tecnologia UHT; estabilidade das proteínas, principalmente as caseínas, que se encontram organizadas na forma de micelas e que tem sido objeto de estudo de cientistas em todo o mundo; pH; balanço salino; presença de microrganismos. Através deste artigo, buscou-se o entendimento do que é o fouling para que seja possível encontrar uma solução para esse problema na indústria laticinista, que afeta não somente a cadeia produtiva, mas também a qualidade do produto final e seu tempo de prateleira, influenciando assim na escolha do consumidor.
Influência do teor de sólidos lácteos na microestrutura de leites fermentados
Authors: Gomes Elisângela Ramieres , Oliveira Mariana Braga de , Silva Paulo Henrique Fonseca da , Perrone Ítalo Tuler , Oliveira Luiz Fernando Cappa de , Stephani Rodrigo
Published: March 2023

Leites fermentados são produtos lácteos, obtidos por coagulação, mediante a diminuição do pH do leite fluido ou reconstituído, adicionado ou não de outros produtos lácteos, por fermentação láctica mediante ação de cultivos de microrganismos específicos. O tipo de processamento e a composição dos ingredientes utilizados, promovem mudanças nas propriedades sensoriais, reológicas e nutricionais dos leites fermentados. Portanto, o objetivo desse trabalho foi avaliar o efeito da adição de quatro concentrações de sólidos totais (9,0%; 12,2%; 15,0% e 18,0% m/m) em leites fermentados, empregando as técnicas de distribuição do tamanho de partículas durante a fermentação e microscopia eletrônica de varredura no produto final. A distribuição do tamanho de partículas mostrou que os leites fermentados com maiores teores de sólidos totais (12,2%; 15,0% e 18,0% m/m) apresentaram maiores valores de d90, ou seja, valores nos quais 90% das partículas estão abaixo deles, quando comparado ao tratamento com 9,0% (m/m) de sólidos. A microscopia eletrônica de varredura mostrou um resultado semelhante, em que o leite fermentado com 9,0% (m/m) de sólidos totais apresentou uma estrutura com poros mais abertos, enquanto os leites fermentados com 12,2%, 15,0% e 18,0% (m/m) de sólidos totais apresentaram uma rede proteica com partes mais compactas. Portanto, leites fermentados com maiores teores de sólidos totais apresentaram um maior tamanho de partículas e uma microestrutura mais compacta. Dessa forma, os métodos de distribuição do tamanho de partículas e microscopia podem ser usados para fornecer informações sobre as características dos produtos de acordo com a demanda dos consumidores.
Preschool Curriculum System Innovation in the Philippines and Indonesia
Authors: Nur Cahyati Ngaisah  , Firman Priyo Suhasto  , Kulsum Nur Hayati
Published: March 2023

The curriculum system in education becomes one of the identities of various countries. The Philippines and Indonesia have different curricula from multiple factors in realizing the nation's ideals, to educate generations who are experts in their fields. The purpose of this research is to find out the curriculum innovations applied in the educational process both domestically and abroad,  one of them is the Philippines which possesses excellence in various educational programs. This research uses a qualitative approach with a literature study method that uses secondary data from multiple national and international journal articles. As for the data analysis technique, it uses qualitative analysis techniques in a deductive way from discussing the preschool education system converging into the curriculum used in the Philippines and Indonesia. The findings from this study are that the education system in Indonesia has almost the same quality as foreign countries. The Philippines designed the K-12 curriculum implemented in preschool by developing various aspects of child development to prepare the child to enter primary school. While in Indonesian curriculum prepares children with disabilities in cognitive development so that they ignore other developments because several elementary school institutions require children to be able to read, write and count.

Abstrak

Sistem kurikulum dalam pendidikan menjadikan salah satu identitas dari berbagai negara. Filipina dan Indonesia memiliki kurikulum yang berbeda dari berbagai faktor dalam mengujudkan cita-cita bangsa, untuk mencerdaskan generasi-generasi yang ahli dibidang kemampuannya. Tujuan dari penelitian ini yaitu untuk mengetahui inovasi kurikulum yang digunakan dalam proses pendidikan baik di dalam negeri maupun luar negeri, salah satunya yaitu negara Filipina yang memiliki keunggulan diberbagai program pendidikan. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi pustaka yang menggunakan data sekunder dari berbagai artikel jurnal nasional dan internasional. Sedangkan untuk teknik analisis data menggunakan teknik analisa kualitatif dengan cara deduktif dari pembahasan sistem pendidikan prasekolah merucut kedalam kurikulum yang digunakan di negara Filipina dan Indonesia. Temuan dari penelitian ini bahwa sistem pendidikan di Indonesia memiliki kualitas yang hampir sama dengan kurikulum mancanegara. Filipina merancang kurikulum K-12 yang diterapkan prasekolah dengan mengembangkan berbagai aspek perkembangan anak untuk mempersiapkan anak ke jenjang Sekolah Dasar. Dan Indonesia untuk mempersiapkan anak terfokus pada perkembangan kognitif sehingga mengabaikan perkembangan yang lain karena beberapa lembaga Sekolah Dasar yang menuntut anak sudah bisa membaca, menulis dan berhitung.
The new normal
Authors: Piercy Marge
Published: March 2023

A new poem by Marge Piercy.
Неодноосная ползучесть при сложном нагружении
Authors: Кичаев Евгений Константинович , Kichaev Eugeny Konstantinovich , Кичаев Пeтр Евгеньевич , Kichaev Petr Eugen'evich
Published: March 2023

На базе модели неполной обратимости деформации ползучести предложены определяющие уравнения для неодноосного напряженного состояния металлов при сложных путях нагружения.
Предполагается независимое развитие тензоров вязкоупругой, вязкопластической и вязкой компонент деформации ползучести.
Кинетика деформирования связывается с исходной и деформационной анизотропией.
Мерой интенсивности ползучести исходно ортотропных материалов принято эквивалентное напряжение, введенное Хиллом.
В этом случае не требуется подобие девиаторов напряжений и деформаций.
Характер деформационной анизотропии связывается со значением вязкопластической компоненты деформации в направлении главных осей тензора напряжений.
Предполагается суперпозиция исходной и деформационной анизотропии.
Испытывались образцы из исходно изотропных материалов: из инструментальной стали 3ХВ4СФ по режимам ее работы в контейнерах для прессования алюминиевых сплавов; из жаропрочного сплава ЭИ437Б по условиям работы дисков и лопаток газотурбинных двигателей.
Расчет реологических коэффициентов исходно изотропных материалов 3ХВ4СФ и ЭИ437Б производился по результатам одноосных испытаний на растяжение образцов при нескольких уровнях начальных напряжений. Проведен сравнительный анализ прогноза при сложном нагружении по предлагаемым уравнениям с результатами испытаний.
Сравнение элементов орбит больших планет, Луны и Солнца с использованием различных математических моделей на интервале времени с 1600 по 2200 гг.
Authors: Заусаев Анатолий Федорович , Zausaev Anatoliy Fedorovich , Романюк Мария Анатольевна , Romanyuk Mariya Anatolievna
Published: March 2023

Проведен анализ точности элементов орбит, полученных по координатам и компонентам скоростей, найденных с помощью коэффициентов многочленов Чебышева планетного каталога DE405. Для исследования на интервале времени с 1600 по 2200 гг. проведено сопоставление элементов орбит, найденных с помощью каталога DE405, а также полученных на основании численного интегрирования уравнений движения, основанных на взаимодействии движущихся материальных тел с окружающим пространством. На примере численного интегрирования уравнений движения Луны показано преимущество использования уравнений движения, основанных на взаимодействии движущихся материальных тел с окружающим пространством по сравнению с релятивистскими уравнениями. На основании сравнения элементов орбит Меркурия, полученных путем решения уравнений, основанных на взаимодействии движущихся материальных тел с окружающим пространством и найденных с помощью использования каталога DE405, показано, что на исследуемом интервале времени элементы орбит практически совпадают. Максимальное расхождение в средней аномалии на конце интервала интегрирования составляет менее $1"$ (секунды дуги). Определены невязки вековых смещений перигелиев для Меркурия, Венеры, Земли + Луны и Марса, значения которых для DE405 соответственно равны: $43.08"$, $8.4"$, $3.83"$ и $1.14"$. Показано, что погрешности вековых смещений перигелиев планет Меркурия, Венеры, барицентра Земли + Луны и Марса, полученные при использовании каталога DE405, принимают следующие значения: $0"$, $6.06"$, $3.83"$ и $1.08"$. Для внешних планет: Юпитера, Сатурна, Урана, Нептуна и карликовой планеты Плутон на основании рассмотренных сравнений различных уравнений движения расхождений элементов орбит не обнаружено. На основании проведенных исследований показано, что использование гармонических координат в релятивистских уравнениях при создании каталога DE405 оправдано только для Меркурия и внешних планет: Юпитера, Сатурна, Урана, Нептуна и карликовой планеты Плутон.
Аналог задачи Трикоми для квазилинейного уравнения смешанного типа с двумя линиями вырождения
Authors: Расулов Хайдар Раупович , Rasulov Xaydar R.
Published: March 2023

Доказана однозначная разрешимость аналога задачи Трикоми для квазилинейного уравнения смешанного типа с двумя линиями вырождения.
Введен класс $R_1$ обобщенных решений в гиперболической части области. Единственность решения доказана методом интегралов энергии. Доказательство существования решения проводится методом интегральных уравнений. Краевая задача сводится к эквивалентной системе интегральных уравнений, разрешимость которой доказана с помощью принципа Шаудера. В результате применения принципа Шаудера получена глобальная разрешимость исследуемой задачи без каких-либо ограничений на размер площади рассматриваемой области и на значение заданных функций.
Колебания пластины с граничными условиями «шарнир--заделка»
Authors: Сабитов Камиль Басирович , Sabitov Kamil Basirovich
Published: March 2023

Изучена начальная задача для уравнения колебаний прямоугольной пластины с граничными условиями типа «шарнир-заделка».
Установлено энергетическое неравенство, из которого следует единственность решения поставленной начально-граничной задачи.
Доказаны соответствующие теоремы существования и устойчивости решения задачи в классах регулярных и обобщенных решений.
Существование решения поставленной задачи проводится методом спектрального анализа и оно построено в виде суммы ортогонального ряда по системе собственных функций соответствующей двумерной спектральной задачи, которая строится методом разделения переменных.
Дано полное обоснование сходимости построенного трехмерного ряда в классе регулярных решений рассматриваемого уравнения. Обобщенное решение определяется как равномерный предел последовательности регулярных решений начально-граничной задачи.
Решение задачи Дородницына-Ладыженского
Authors: Сизых Григорий Борисович , Sizykh Grigory Borisovich
Published: March 2023

Статья посвящена строгому доказательству утверждения,
что энтропия принимает максимальное значение на поверхности тела с затупленной носовой частью, обтекаемого сверхзвуковым потоком, при наличии плоскости симметрии течения.
Это очевидно для тел вращения при нулевом угле атаки, а численными расчетами и экспериментально установлено при ненулевых углах атаки.
Доказательство сводится к обоснованию того, что лидирующая линия тока (линия тока, пересекающая скачок по нормали) заканчивается на теле.
Иными словами, лидирующая линия тока и линия торможения совпадают.
Такое доказательство получено Г. Б. Сизых в 2019 году для общего пространственного случая (не только для течений с плоскостью симметрии).
Это достаточно сложное доказательство основано на критерии Зоравского, опыт использования которого имеет лишь узкий круг специалистов, и опирается на предположение о непрерывности вторых производных плотности и давления.
В настоящей статье для практически важного случая течений с плоскостью симметрии (в частности, обтекание тел вращения при ненулевом угле атаки) предлагается оригинальное простое доказательство, для которого достаточно непрерывности только первых производных полей плотности и давления и не требуется использования критерия Зоравского.
Математическое прогнозирование вероятности столкновения частиц в процессе детонационного напыления
Authors: Ганигин Сергей Юрьевич , Ganigin Sergey Yur'evich , Гречухина Мария Сергеевна , Grechukhina Maria Sergeevna , Нечаев Алесандр Сергеевич , Nechaev Alexander Sergeevich , Мурзин Андрей Юрьевич , Murzin Andrey Yuryevich , Воронцова Валерия Андреевна , Vorontsova Valeria Andreevna
Published: March 2023

Представлены методы математического прогнозирования вероятности столкновения частиц разнородных материалов в процессе детонационного напыления композиционных покрытий. Вследствие разных свойств исходных порошковых материалов (массы, аэродинамического сопротивления) показатели качества композиционных покрытий определяются не только параметрами движения частиц, но и их взаимным положением в потоке продуктов детонации. В случае использования реагирующих компонентов взаимодействие расплавленных частиц в потоке может привести к протеканию химических реакций и образованию новых материалов на подложке, созданию неоднородной структуры покрытия и ухудшению его прочностных и адгезионных свойств. Предварительный прогноз вероятности столкновения частиц до соприкосновения с поверхностью изделия дает возможность до проведения натурных испытаний сделать вывод о получении качественных показателей покрытия.
Puestos de frutas y verduras en plazas de abastos: del diseño comunitario al urbanismo táctico
Authors: Aparicio-Rengifo Reynaldo , Flórez-González Fernando , Fonseca-Laverde Kevin , Gélvez-Chala Daniel , Briceño-Bello Manuela
Published: March 2023

Las plazas de abastos en Colombia son reconocidas como el lugar de encuentro entre lo rural y lo urbano. Históricamente, la actividad de comprar ha permitido mantener la interacción entre la ciudadanía y los productores campesinos, a través de los comerciantes informales, que realizan sus actividades económicas bajo condiciones deplorables en su espacio de trabajo. En ese orden de ideas, el presente estudio tuvo como objetivo establecer los lineamientos para analizar y mejorar el diseño de los puestos de frutas y verduras, como medida para dignificar las condiciones de trabajo del comercio informal de la plaza de abastos de Palmira, Valle del Cauca, Colombia. La investigación propone el desarrollo de una metodología de diseño comunitario para los puestos de frutas y verduras de siete comerciantes de la plaza de abastos de Palmira, a través de tres componentes: 1) investigación in situ de la cultura material, 2) diseño comunitario y 3) el urbanismo táctico con la producción del mobiliario, para evaluar la experiencia. La metodología logró establecer un punto de encuentro entre el conocimiento científico de un equipo de trabajo interdisciplinario y los saberes populares de los vendedores informales, y generar con ello una propuesta con una potencial replicabilidad en otros mercados de Latinoamérica.
Cultura, prácticas artísticas y espacio urbano en la Localidad de San Cristóbal: el caso del suroriente, Bogotá
Authors: Cortés-Garzón Liliana
Published: March 2023

Se analizan algunas prácticas artísticas en un entorno urbano informal en la Localidad de San Cristóbal, en Bogotá, D. C. La relación que establecen los entornos comunitarios frente a las prácticas urbanas de carácter informal presenta un uso del espacio público con actividades de carácter cultural como parte de redes asociativas entre agrupaciones comunitarias, y una gran tipología de artes que se practican en espacios culturales como formas de resistencia a violencias simbólicas y físicas con las cuales se convive en el espacio urbano. De esta manera, las prácticas artísticas logran convertirse en una alternativa de transformación cultural como prácticas que se convierten en posibilidades y formas de vida innovadoras y de carácter colectivo, una alternativa cultural que promueve la apropiación territorial, la defensa de derechos frente a la informalidad en la construcción urbana, y la defensa de las reservas naturales y de las culturas como formas de conocimiento.
Historia, memoria e identidad. Una propuesta de recuperación histórica de los barrios populares en la ciudad de Bogotá. El caso de la localidad de Chapinero
Authors: López-Borbón Walter
Published: March 2023

Lograr una mirada integral del territorio, que incluya tanto la formalidad como la informalidad urbanas, no solo es una postura política y ética, sino que, de manera estrictamente objetiva, es la única posibilidad de comprender los diferentes procesos de poblamiento de las ciudades latinoamericanas y su accionar, así como la única forma de prever posibles tendencias futuras. Esto implica un trabajo mancomunado con las comunidades, con miras a una reconstrucción memorial de amplios sectores de la población. El presente artículo resume los principios teóricos, conceptuales e instrumentales en aras de proponer una metodología para la recuperación histórica de los barrios, su sistematización y su socialización. A partir de la crónica, de diferentes testimonios y de la contextualización de los hechos políticos y sociales, registrados simultáneamente, se elaboran Líneas de tiempo que, enmarcadas en el diálogo de saberes, permitirán una nueva visión de la historia de la ciudad. Para su socialización se propone conformar una plataforma de libre acceso, denominada WikiBarrio, con el ánimo de garantizar la mayor y la mejor participación de las comunidades.
PetPS: Supporting Huge Embedding Models with Persistent Memory
Authors: Xie Minhui , Lu Youyou , Wang Qing , Feng Yangyang , Liu Jiaqiang , Ren Kai , Shu Jiwu
Published: March 2023

Embedding models are effective for learning high-dimensional sparse data. Traditionally, they are deployed in DRAM parameter servers (PS) for online inference access. However, the ever-increasing model capacity makes this practice suffer from both high storage costs and long recovery time. Rapidly developing Persistent Memory (PM) offers new opportunities to PSs owing to its large capacity at low costs, as well as its persistence, while the application of PM also faces two challenges including high read latency and heavy CPU burden. To provide a low-cost but still high-performance parameter service for online inferences, we introduce PetPS, the first production-deployed PM parameter server. (1) To escape with high PM latency, PetPS introduces a PM hash index tailored for embedding model workloads, to minimize PM access. (2) To alleviate the CPU burden, PetPS offloads parameter gathering to NICs, to avoid CPU stalls when accessing parameters on PM and thus improve CPU efficiency. Our evaluation shows that PetPS can boost throughput by 1.3 -- 1.7X compared to PSs that use state-of-the-art PM hash indexes, or get 2.9 -- 5.5X latency reduction with the same throughput. Since 2020, PetPS has been deployed in Kuaishou, one world-leading short video company, and successfully reduced TCO by 30% without performance degradation.
Application of machine learning approach in emergency department to support clinical decision making for SARS-CoV-2 infected patients
Authors: Casano Nicolò , Santini Silvano Junior , Vittorini Pierpaolo , Sinatti Gaia , Carducci Paolo , Mastroianni Claudio Maria , Ciardi Maria Rosa , Pasculli Patrizia , Petrucci Emiliano , Marinangeli Franco , Balsano Clara
Published: March 2023

To support physicians in clinical decision process on patients affected by Coronavirus Disease 2019 (COVID-19) in areas with a low vaccination rate, we devised and evaluated the performances of several machine learning (ML) classifiers fed with readily available clinical and laboratory data. Our observational retrospective study collected data from a cohort of 779 COVID-19 patients presenting to three hospitals of the Lazio-Abruzzo area (Italy). Based on a different selection of clinical and respiratory (ROX index and PaO2/FiO2 ratio) variables, we devised an AI-driven tool to predict safe discharge from ED, disease severity and mortality during hospitalization. To predict safe discharge our best classifier is an RF integrated with ROX index that reached AUC of 0.96. To predict disease severity the best classifier was an RF integrated with ROX index that reached an AUC of 0.91. For mortality prediction the best classifier was an RF integrated with ROX index, that reached an AUC of 0.91. The results obtained thanks to our algorithms are consistent with the scientific literature an accomplish significant performances to forecast safe discharge from ED and severe clinical course of COVID-19.
People Want Optimal Deterrence – Just a Little Bit
Authors: Kłusek Michał
Published: March 2023

Psychological studies of punitive intuitions demonstrate that the economic theory of optimal deterrence is fundamentally counterintuitive. We punish in response to the moral blameworthiness of the crime with little regard for the consequences. But it is less clear whether optimal deterrence is acceptable. When the law is not accepted by the community it governs, its crime control efficiency suffers. If optimal deterrence is wholly unacceptable, then it is counterproductive as a guide to penal policy. I administered an online survey to university students to examine the acceptability of different applications of optimal deterrence theory. The participants rejected nearly all of the applications, with the sole exception of an increase in punishment severity on the general policy level. They were also more willing to accept smaller, rather than bigger, changes of punishment severity; and increases, rather than decreases of punishment. The results suggest penal policy may be slightly adjusted in the direction suggested by economic analysis of criminal law without a major loss to the law’s moral credibility – especially if the adjustment involves an increase in punishment magnitude.
The Politics Settlement of Land Tenure Conflicts During Jokowi’s Presidency
Authors: Handayani I Gusti Ayu Ketut Rachmi , Karjoko Lego , Jaelani Abdul Kadir , Barkhuizen Jaco
Published: March 2023

This study was prompted by the high rate of land tenure conflicts in forest areas. In the 2015-2020, a total of 10,000 conflicts were experienced in Indonesia, and a legal approach was used to conduct this normative study. Furthermore, the data collection was through literature and the legal norm method was used for analysis. The results showed that the government reduced the treatment of the conflict by establishing the Directorate of Customary Forest Tenure Conflict Management institutions and legal products of Presidential and Ministerial Regulations. However, the forest land tenure conflict was not resolved during the Joko Widodo administration and was increased by 50 percent from the previous administration of President Susilo Bambang Yudhoyono. Meanwhile, this conflict can be resolved through the role affirmation of State Administrative Law in determining forest areas with legal certainty and justice. The assertion was conducted by enforcing this law against licensing violations and building integrated conflict resolution in creating legal certainty and equity.
The Regulation of Disorgement in the Indonesia Capital Market: Remaining Concerns and Lessons from US
Authors: Pratama Anugrah Muhtarom , Pati Umi Khaerah , Tejomurti Kukuh , Mohamad Mohamad Hanapi
Published: March 2023

This study aimed to analyse the authority that recently empowered the Indonesia Financial Services Authority (OJK) based on OJK Regulation Number 65/POJK.04/2020 in conjunction with OJK Circular 17/SEOJK.04/2021. OJK was empowered to pursue disgorgement in the Indonesian capital market as a new tool for protecting investors by analyzing changes in disgorgement enforcement practices in the US. This study used a doctrinal legal method with a comparative approach. The comparative approach was used to examine the possibility of strengthening disgorgement enforcement applicable to current Indonesian law on such practices in the US. Disgorgement in Indonesia is similar to the previous one in the US. The disgorgement authority in the Capital Market Act was not explicit because OJK still interpreted “written orders” such as “grant relief ancillary to an injunction” when disgorgement was first introduced by the SEC. This poses challenges in calculating the number of disgorgements that may be limited or canceled due to a lack of strong legal remedies when the violator does not pay the disgorgement. Considering practical experience in the US from Texas Gulfur Sulfur to Kokesh and Liu, disgorgement in Indonesia needs strengthening to maintain enforcement sustainability and avoid setbacks. Therefore, the strengthening should involve placing the disgorgement authority in the Capital Market Act, providing Standard Guidelines for the Calculation of Disgorgement Amounts and and establishing regulations on Procedures for Civil Lawsuits by OJK. The results are expected to be a reference for regulators and legislators to improve enforcement of the disgorgement regime in Indonesia.
Manual de prácticas de laboratorio de geología
Authors: Javier Enrique Peña Manosalva,
Published: March 2023

La geología hace parte de las 4 áreas básicas de las ciencias de la tierra. Encargada de estudiar los eventos que han ocurrido desde su formación hasta la actualidad en la tierra, los materiales que la constituyen y su estructura, aportando información relevante para el conocimiento del medio natural y desarrollo de proyectos sostenibles con el ambiente. Este manual de prácticas de laboratorio de Geología pretende ser una material pedagógico que le permita al estudiante un manejo sencillo y práctico de conceptos, instrumentos, equipos y procedimientos que permite el desarrollo de competencias y habilidades del hacer científico mediante la demostración y/o comprobación de teorías e hipótesis, al igual que la argumentación escrita de los resultados obtenidos en el desarrollo de las prácticas mostrando la apropiación del conocimiento en forma lógica y crítica plasmado en el syllabus del espacio académico. En este manual encontrará 11 prácticas de laboratorio que guiarán al estudiante en la manera de presentar los preinformes e informes, clasificar minerales, rocas y suelos, obtener muestras de suelos, interpretar estructuras geológicas producto de la incidencia de esfuerzos y analizar información en mapas geológicos.
Per studiare il vocabolario del passato
Authors: Burgassi Cosimo , Guadagnini Elisa
Published: March 2023

This paper aims to propose a new method for describing the lexicon of a language in a specific period of its history. The first paragraph outlines the two main ideas to be found in the studies concerning both synchronic and diachronic lexicology. In the second paragraph our method for lexical inquiry is presented together with its core concepts, which are textual Corpus Representativeness, Connotation, Connotation Rate (Quoziente Connotativo, QC) and word Position in the Center-Periphery Vocabulary Model. The third paragraph sketches two possible research lines, the first one regarding the lexicon of a given historical period (Old Italian), the second dealing with the comparison between two different linguistic historical phases (Old Italian vs. Contemporary Italian).
Using keywords in the automatic classification of language of gender violence
Authors: Castro Mosqueda Héctor , Rico Sulayes Antonio
Published: March 2023

This paper employs lexical analysis tools, quantitative processing methods, and natural language processing procedures to analyze language samples and identify lexical items that support automatic topic detection in natural language processing. This paper discusses how keyword extraction, a technique from corpus linguistics, can be employed in obtaining features that improve automatic classification; in particular, this research is concerned with extracting keywords from a corpus obtained from social networks. The corpus consists of 1,841,385 words and is subdivided into three sub-corpora that have been categorized according to the topic of the comments in each one of them. These three topics are violence against women, violence against the LGBT community, and violence in general. The corpus has been obtained by scraping comments from YouTube videos that address issues such as street harassment, femicide, feminist movements, drug trafficking, forced disappearances, equal marriage, among others. The topic detection tasks performed with the corpus extracted from the social media showed that the keywords rendered a 98% accuracy when classifying the collection of comments from 51 videos, as one of the three categories mentioned above, and 92% when classifying almost 7,500 comments individually. When keywords were removed from the classification task and all words were used to perform the classification task, accuracy dropped by an average of 17%. These results support the argument for keyword relevance in automatic topic detection.
Influence of the number of layers on the strength of beech laminated elements in the three-point flexural test,
Authors: Réh Roman , Hitka Miloš , Naď Milan , Langová Nadežda , Rolník Ladislav , Lee Seng Hua , Sydor Maciej
Published: March 2023

A chair is a piece of furniture whose elements are loaded with relatively high forces. The strength of these elements is vital for the safety of using this type of furniture. The research aims to test the chair material system made of beech wood. The authors analyzed laminated elements with 9, 11, and 13 layers of veneers. The veneers were 1.23 mm thick, with perpendicular fiber directions in adjacent layers, and bonded with 220 g/m2 of PVAc adhesive. The moisture content of the elements was 6 ± 1%. A three-point bending flexural test was performed to determine the stress-strain response of the tested three variants. A complementary numerical analysis allowed a more precise comparison of the three analyzed laminated elements variants. It was confirmed that all variants exceed the desired minimal values in chair support design. Moreover, the average strength values for tested laminated elements, differing in the number of veneers, were sufficient even with a reduced number of veneer layers. The experiments and numerical analysis results confirmed the usability of the three tested types of beech laminated elements to be used as highly loaded chair elements.
Himno Patriótico de Alejandro Cardona y Llorens (1827-1899)
Authors: Vargas Cullell María Clara , Alfaro Bogantes Luis
Published: March 2023

El presente artículo estudia las diversas facetas del oficio musical de Alejandro Cardona y Llorens, músico migrante español que se estableció en Costa Rica desde 1853. Las actividades musicales que emprende a lo largo de su vida reflejan el proceso de profesionalización del oficio musical que inició en el país a partir de la segunda mitad del siglo XIX. Es también un ejemplo de cómo la migración ha sido un elemento que ha contribuido a la diversificación y consolidación de la práctica musical del país en diversos momentos de la historia.
Arte, feminismo y poder: Lxs cuerpxs con vulva en la obra de Anna Matteucci
Authors: García Zamora Ericka
Published: March 2023

El artículo estudia el vínculo entre el arte, el feminismo y el poder, expresado en las obras de la artista costarricense Anna Matteucci. Se analizan piezas y espacios creativos que abordan cuestiones sobre sexualidad, género, familia y religión. Se utilizan referentes teóricos sobre poder, arte y discurso, los cuales se basan en Foucault (1988), Castells (2009), Foster (2017), Giunta (2014), Badiou (2013), Bourriaud (2008), Antivilo (2013) y Escobar (2021). Todo lo vinculado con género, sexualidad y familia se encuadra en los planteamientos de Butler (2007) sobre feminismo y las denominadas identidades nómadas. Se concluye que la obra de Matteucci evidencia formas determinadas de pensarse como mujer en el contexto de una sociedad violenta que censura e invisibiliza el cuerpo y su diversidad, por lo que expresa un discurso contrahegemónico que, como tal, es en esencia político y no autorizado, dado su contenido subversivo.
Locura-arte-surrealismo y Valerie Solanas
Authors: Vargas Vargas Karla
Published: March 2023

A partir de algunas categorías antipsiquiátricas y surrealistas, se analiza la institución psiquiátrica como aparato coercitivo que posiciona, en algunas ocasiones, a la persona loca y a la persona artista en un espacio negativo, dificultándoles la posibilidad de ser, hacer y dejarse ser y de fluir en una suerte de escritura libre. La locura y el espacio vivencial del artista, sea surrealista o no, son aquí entendidos como alternativa, como respuesta válida (no patologizada ni patologizante) ante los mandatos y restricciones capitalistas y, en especial, ante el imperio del racionalismo dominante. Asimismo, como ejemplo y crítica de lo anteriormente señalado, se estudia de manera general la controversial historia de Valerie Solanas quien, como mujer, compacta en vida propia los efectos negativos del sistema sociopolítico, económico y cultural dominante, de base patriarcal, y vive a flor de piel el desprecio social hacia la locura y la vida de quienes se dedican al arte.
A orillas del infinito: el nuevo arte indio entre Octavio Paz y el Grupo 1890
Authors: Martínez Milantchi José Darío
Published: March 2023

Este estudio examina la relación entre Octavio Paz y el Grupo 1890, un colectivo de jóvenes artistas indios que tuvieron su única exhibición en Nueva Delhi en 1963. El análisis se centra en el diálogo que surge del catálogo de la exhibición, que incluye un ensayo introductorio de Paz y el manifiesto provocador del Grupo. A través de una lectura de las aproximaciones de Paz y el grupo a la novedad artística, el rol de lo nacional y la relación arte-realidad, este estudio busca trazar un diálogo artístico sur-sur basado en la incongruencia y la heterogeneidad. El poeta ve en las obras exhibidas la expresión de una vanguardia global, influenciada por movimientos europeos, construida en oposición a la tradición folclórica nacional y abocada a una exploración profunda de la realidad sin caer nunca en el realismo. Mientras tanto, el manifiesto del Grupo 1890 proyecta una visión casi nihilista que, a pesar de reconocer un predecesor europeo en su dedicatoria, rechaza su tradición nacional sin decantarse por pretensiones universalistas y conceptualiza el arte como un campo independiente y separado de lo real.
La mascarilla como arte: expresiones artísticas sobre las enfermedades y el COVID-19
Authors: Sequeira-Rovira Paula
Published: March 2023

El presente artículo se interesa por las expresiones de arte ligadas a la enfermedad. Aunque históricamente dichas representaciones han mostrado cercanía hacia la fealdad o el desagrado de lo patológico, en tiempos de COVID-19 se producen otro tipo de simbolismos. En el caso de la mascarilla quirúrgica, es utilizada no solo como una metáfora para mostrar su contacto directo con la pandemia producida por el SARS-CoV-2, sino también para expresar ideas individualistas del manejo de la pandemia y una gestión más personal de la crisis sanitaria. Para hacer el análisis, se dio especial importancia a las exposiciones de “Mascarillas x artistas”, organizada por el Museo de Jade en Costa Rica, y “Mascarilla del arte. Mi única protección” de Puerto Rico. Asimismo, se mencionaron otros espacios artísticos que se interesan por el COVID-19 y en el cual este dispositivo tiene un lugar prioritario.
Chlorogenic acid alleviated testicular inflammation and apoptosis in tunicamycin induced endoplasmic reticulum stress
Authors: Komeili–Movahhed Tahereh , Heidari Fatemeh , Moslehi Azam
Published: March 2023

Purpose

Chlorogenic acid (CA) is a polyphenolic compound, found in many herbs and foods including coffee, berries and potatoes. Anti-inflammatory, anti-oxidant, anti-cancer and anti-apoptotic effects of CA have been proven in many tissues. Testicular inflammation and apoptosis are essential factors in male infertility that could result from endoplasmic reticulum (ER) stress. ER stress leads to unfolding and misfolding of nascent proteins and thereby provokes cellular inflammatory and apoptotic pathways. This study was designed to assess the effects of CA on ER stress-induced testis inflammation and apoptosis.

Methods

To do this, male mice were divided into six groups. The control, vehicle and CA groups received saline, DMSO and 50 mg kg−1 CA. Tunicamycin (TM (was injected to induce ER stress (TM group). In the CA20-TM and CA50-TM groups, 20 mg kg−1 CA and 50 mg kg−1 CA were administered one hour before TM injection. After thirty hours, animals were sacrificed and testes were removed. Hematoxylin & eosin staining, ELISA assay and real-time PCR were performed.

Results

CA administration significantly downregulated gene expression of TNFα, IL6, P53, Bax/Bcl2 ratio and caspase3. It also reduced testis levels of ALP, NF-κB, TNFα and caspse3. Finally, CA relieved structural changes in seminiferous tubules.

Conclusions

This study demonstrated that the positive effects of CA on the attenuation of ER-stress induced inflammation and apoptosis might be due to the inhibition of NF-κB and thereby suppression of inflammatory and apoptotic pathways.
Allergic rhinitis and dental caries: A systematic review
Authors: Calvo-Henriquez Christian , Rodríguez-Rivas Paula , Mayo-Yáñez Miguel , González-Barcala Francisco J. , Boronat-Catala Borja , Martins-Neves DDS Silvia , Martínez-Capoccioni Gabriel , Martin-Martin Carlos
Published: March 2023

Objective: Dental caries is one of the most common chronic diseases affecting millions of people globally. Some studies revealed the presence of bidirectional relationship between allergic rhinitis (AR) and oral diseases, with each disease having a potential impact on the other. In this study we aimed to systematically review the literature and analyze the available evidence regarding whether AR contributes to the development of dental caries.
Methods: Three authors, members of the YO-IFOS rhinology study group, independently analyzed the data sources (Pubmed, the Cochrane Library, EMBASE, SciELO) for papers assessing the relationship between rhinitis and caries, in adult and pediatric patients.
Results: Eight studies met the inclusion criteria (87612 participants). Six studies were performed in children. A total of three studies found an association between AR and dental caries. Only two studies had adjusted the measure of effect for potentially confounding variables. Regarding the quality of the selected studies according to the NICE classification, the most observed methodological limitations detected were: (1) the cross-sectional design of the included studies which could have introduced a simultaneity bias, and (2) not clearly reporting the inclusion and exclusion criteria.
Conclusion: This systematic review can neither confirm nor deny the presence of an association between AR and caries. Despite the evidence is very scarce to conclude a relationship between AR and caries, the option for examining patients with repetitive caries by an otolaryngologist and those with AR by odontologist should be considered, as these examinations do not possess any risk for the patient.