bluuebunny/crossref_metadata_2025 huggingface dataset:
Reinterpretation of Gender Concept and Its Influence on Preservation of Barong Show Performance in Blora
Authors: Cahyono Agus , Sunarto Sunarto , Ary Deasylina da , Prameswari Nadia Sigi , Guntaris Endik
Published: December 2023

Barongan Blora is a traditional folk dance in Central Java that has existed since 1830. The passage of time brings up new social conceptions that influence the implementation of Barongan performances, particularly those relating to gender. This research aims to look into the gender roles of Barongan dancers and how they interact with social and cultural components of society. Gender interpretation aims to understand the social construction of men’s and women’s roles in society. These roles include male and female dancers whose motions express diverse traits while maintaining the performance’s significant values. This study employs a qualitative research design with case studies on various Barongan groups in Blora, Indonesia. In May 2023, data was gathered through interviews, observation, and documentation. The results suggest that cat motions dominate the Barongan dance steps, which are supported by strong, energetic, and nimble characters. On the other hand, each character’s movements are tailored to the roles and the dancers who portray them. Male dancers are cast as characters who appear strong and emphasize masculine attributes, such as Barongan, Gembong Amijoyo, Joko Lodro, Untup, and Nayantaka. Meanwhile, female dancers who play male characters, such as Barongan and Jathilan, must be agile, strong, and feminine. Gender distinctions in Barongan performance can be noticed in the movements created. Still, there are no substantial disparities in physical appearance between male and female dancers because both needed a physique corresponding to the characters being played. The Barongan performance also impacts society’s social and cultural features. Regarding social qualities, Barongan embodies the populist traits of the Blora people, which are based on humanist principles. In terms of culture, Barongan Blora has evolved to keep up with changing times, yet it remains and can be appreciated by all levels of society. Due to its uniqueness, Barongan’s preservation is still carried out in line with the times while maintaining cultural values and content in physical and non-physical forms.
Investigation of the Effect of Physiotherapists' Basic Psychological Needs in Leisure on Life Satisfaction with Structural Equation Model
Authors: EREN Muhammed Ömer , DOKUZOĞLU Gökhan , ZORBA Ercan
Published: December 2023

This study aimed to examine the effect of physiotherapists' basic psychological needs in leisure on life satisfaction. Relational screening method was used in our study which was conducted according to the general screening model. The data were collected using the personal information form developed by the researchers in the first part, the Basic Psychological Needs Scale in Leisure Activity (BPNSLA) in the second part, and the Life Satisfaction Scale in the third part. The data were analysed with AMOS 21.0 and SPSS 25.0 package programmes. According to the result of the Independent Sample T-test between the Basic Psychological Needs in Leisure Activity and Life Satisfaction of the participants, a statistically significant difference was detected in favour of male participants only in the variable of relatedness, and according to the result of the Anova test between professional experience variables and Basic Psychological Needs in Leisure activity and Life Satisfaction, a statistically significant difference was detected in the total score of Basic Psychological Needs in Leisure activity, competence and relatedness sub-dimensions. Moreover, according to the result of the Independent Sample T-Test between marital status variables and Basic Psychological Needs in Leisure Activity and Satisfaction with Life, a statistically significant difference was detected in all variables except the relatedness variable to Basic Psychological Needs in Leisure Activity, and according to the result of the ANOVA test between Weekly Leisure variable and Basic Psychological Needs in Leisure Activity and Satisfaction with Life, a statistically significant difference was detected only in the autonomy sub-dimension of Basic Psychological Needs in Leisure Time (p
Determining the most important game-related statistics in Euroleague basketball competitions: A five-year follow-up
Authors: YILMAZ Berk , IŞIK Özkan , DOĞAN İlkay
Published: December 2023

The purpose of this study was to investigate the game-related statistics in the Play-Off and Final Four rounds of the Euroleague basketball competitions held between 2014 and 2018. In the study, the game-related statistics of 60 teams that participated in the Euroleague Play-Off and Final Four rounds between 2014 and 2018 were evaluated. The independent samples t-test was used to compare the game-related statistics of the two groups. The linear discriminant analysis was used to determine the important game-related statistics between the teams that qualified and those that were eliminated. The results of the study showed that there was a statistically significant difference between the game-related statistics of the two groups in the Play-Off competitions. This difference was seen in the free throw percentage, fouls committed, and performance efficiency scores. As a result of the discriminant analysis, it was found that foul, three-point field-goal percentage, performance efficiency score, turnover, free-throw percentage, and two-point field-goal percentage are important game-related statistics in qualifying the Play-Off round. When the game-related statistics of the two groups in the Final Four were compared, it was seen that only three-point field-goal percentage was an effective variable in becoming the champion. According to the results of the discriminant analysis, turnover, defensive rebound, and total rebound are important game-related statistics to being an Euroleague champion. In conclusion, it is thought that being the Euroleague champion in the Euroleague, it is necessary to have a lower number of turnovers and a defensive game.
On expand-contract plasticity in quasi-metric spaces
Authors: Zavarzina O.O.
Published: December 2023

It is known that if any function acting from precompact metric space to itself increases the distance between some pair of points then it must decrease distance between some other pair of points. We show that this is not the case for quasi-metric spaces. After that, we present some sufficient conditions under which the previous property holds true for hereditarily precompact quasi-metric spaces.
On compressed zero divisor graphs associated to the ring of integers modulo $n$
Authors: Aijaz M. , Rani K. , Pirzada S.
Published: December 2023

Let $R$ be a commutative ring with unity $1\ne 0$. In this paper, we completely describe the vertex and the edge chromatic number of the compressed zero divisor graph of the ring of integers modulo $n$. We find the clique number of the compressed zero divisor graph $\Gamma_E(\mathbb Z_n)$ of $\mathbb Z_n$ and show that $\Gamma_E(\mathbb Z_n)$ is weakly perfect. We also show that the edge chromatic number of $\Gamma_E(\mathbb Z_n)$ is equal to the largest degree proving that $\Gamma_E(\mathbb Z_n)$ resides in class 1 family of graphs.
Enteroinvasive Escherichia coli infection in a noncompliant HIV patient
Authors: Youssef  Dima , Lal Shankar , Patel Paras
Published: December 2023

Poorly controlled HIV infection increases the risk of opportunistic infections. We are presenting here a case of an HIV patient who was non-compliant with highly active antiretroviral therapy (HAART) regimen and who developed a diarrheal illness secondary to enteroinvasive Escherichia coli (EIEC) infection. The patient presented with severe gastrointestinal symptoms including frank bloody diarrhea, and febrile illness. He was eventually diagnosed with EIEC infection. We discuss the challenges faced in managing this patient and the potential consequences of medication noncompliance in the context of HIV.
Determination of 41Са content in NPP radioactive materials
Authors:   Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine, Zheltonozhskyi V.O. , Myznikov D.E. , Savrasov A.M. , Slisenko V.I. , Bondarkov D.M.
Published: December 2023

The γ-spectra were measured of the radioactive material of the ZNPP which was irradiated by bremsstrahlung with end-point energy 18.5 MeV. Using the ratio of the 47Ca and 58Co activities, the cobalt and calcium mass ratio was determined. Using the obtained data and the measured 60Co activity in the studied sample, a method for determining the 41Ca activity was developed.
The potential of the modified Thomas - Fermi method and its analytical representation on the example of the interaction of 16O with tin isotopes 112,114,116,118,120,122,124Sn
Authors:   Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine, Nesterov V.O.
Published: December 2023

Nucleon distribution densities and nucleus-nucleus interaction potentials for the 16O nucleus and 112,114,116,118,120,122,124Sn isotopes were calculated within the framework of the modified Thomas - Fermi method, taking into account all terms to the second-order of ħ in the quasiclassical expansion of kinetic energy. Skyrme forces dependent on the nucleon density were used as nucleon-nucleon interaction. A successful parameterization was found for the obtained potential, which allows to present it in an analytical form.
Estimation of the reserve capacity of Myodes glareolus after acute irradiation using hematological indicators
Authors:   Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine, Ganzha O.B. , Pavlovskyi V.V.
Published: December 2023

The problem of identifying the sensitivity of living organisms to ionizing irradiation remains relevant, considering the spread of anthropogenic environmental pollution. The study on the effect of single X-ray irradiation (1,5 Gy) on peripheral blood of bank voles (Myodes glareolus (Schreber, 1780)) captured within territories with background radiation level was conducted. Hematological indicators, characterizing the overall condition of performance of the body, were determined dynamically on the first and seventh days after exposure to detect both early changes and the rate of recovery processes. The patterns and features of the main components of leukocyte formula found in peripheral blood of irradiated animals are being discussed. Differences between irradiated and control mouse-like rodents are shown, using parameters of erythrocytes and leukocytes. The analysis of changes in the peripheral blood of irradiated bank voles indicates the high reserve capacity of the body, according to its ability to restore homeostasis.
Influence of dead layer on the response function of planar and coaxial Ge detector using Monte Carlo method
Authors:   Nuclear and Radiological Safety Research Center, Egyptian Atomic Energy Authority, Cairo, Egypt, El-Tayebany R.A. , Shaaban N.
Published: December 2023

Germanium crystals have a dead layer that causes a decrease in efficiency since the layer is not useful for detection but strongly attenuates photons. The thickness of this inactive layer is not well known due to the existence of a transition zone where photons are increasingly absorbed. Therefore, using data provided by manufacturers in the detector simulation model, some strong discrepancies appear by changing the dead layer. Investigations into the Ge detector response functions for gamma rays have been conducted using straightforward physical mechanisms implemented by Monte Carlo simulations. The detector response function feature's most probable interaction mechanisms are described. The Monte Carlo method is applied to simulate the calibration of a HPGe detector in order to determine the total inactive germanium layer thickness and the active volume that is needed in order to study the response function for both types of detectors. Results indicated a strong impact of dead layer variations on the response function of the simulated detectors.
Acknowledgment
Authors:   Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine, Kyiv INR
Published: December 2023

The NPAE Editor-in-chief and the whole NPAE Editorial Board are extremely grateful to our reviewers. Their expertise knowledge, time and efforts spent for reviewing the manuscripts submitted to NPAE helped to improve their scientific quaility and to enhance scientific level of our journal.
Augmented Reality and STEAM Learning in Primary Education
Authors: Delcheva Darina , Zhelyazkova Mariya
Published: December 2023

The article reveals the essence of augmented reality and its benefits for education, focusing on its application in STEAM education in primary school. It describes a STEAM framework of an implemented augmented reality 3rd grade lesson – From the Depths of The Sea. A follow-up evaluation of acquired knowledge during the STEAM lesson, is compared to the knowledge acquired during regular class with traditional methods.
The Unique Schools of Arts in Plovdiv – Past, Present and Future
Authors: Kamburski Petar
Published: December 2023

The article presents the concept of a research project aimed at establishing and cataloging the unique vocational schools in Bulgaria, researching their history, current state and future development and popularizing the experience of teachers in preparing students for specific professions, for which these schools offer vocational training. Three art schools in the city of Plovdiv are represented - National School of Music and Dance Arts ‘Dobrin Petkov’, National High School of Stage and Screen Arts and National High School of Arts ‘Tsanko Lavrenov’. Included are excerpts from interviews, conducted with their principals. Conclusions are drawn in regards to what distinguishes each of the three schools and what makes them similar.
Performance of wrestlers at the Olympic Games: gender aspect
Authors: Curby David , Dokmanac Milorad , Kerimov Fikrat , Tropin Yrui , Latyshev Mykola , Bezkorovainyi Dmytro , Korobeynikov Georgiy
Published: December 2023

Background and Study Aim. With the increasing popularity of freestyle wrestling, the scientific community is paying more attention to gender factors that may influence the performance and success of competitive activities.

The aim of study to determine differences in performance indicators between male and female wrestlers in the Olympic Games 2021.

Material and Methods. The study included 192 athletes, consisting of 96 male wrestlers and 96 female wrestlers. An analysis of match records and video footage was conducted for women's (n=113) and freestyle (n=114) wrestling at the 2021 Tokyo Olympic Games. The assessment of performance indicators utilized an expert evaluation method. Statistical analysis of the obtained data was carried out using licensed Excel spreadsheet software. For categorical data, results were expressed in absolute numbers and percentages.

Results. Based on the analysis of competitive activities at the 2021 Olympic Games, 12 primary technical-tactical actions were identified. The most frequently employed actions were in the standing position: leg attacks, with male wrestlers performing it 35.8% of the time and female wrestlers 30.3%; in the ground position, male wrestlers employed gut wrench (7.6%), while female wrestlers used ankle lace (9.4%). It was found that male wrestlers and female wrestlers accumulated approximately the same number of points for their actions: male wrestlers (926 points) and female wrestlers (912 points). The effectiveness in the standing position was higher for male wrestlers (720 points) than for female wrestlers (621 points). In the ground positions, female wrestlers demonstrated better effectiveness (291 points) than male wrestlers (206 points). The number of points deducted for rule violations was significantly lower for female wrestlers (8 times) compared to male wrestlers (27 times). Time stoppages during challenge reviews were fewer for female wrestlers (7 times) compared to male wrestlers (18 times).

Conclusions. The conducted research indicates differences in the performance indicators of freestyle wrestling between men and women. Male wrestlers employ more actions in the standing position (81.7%) than female wrestlers (70.7%). Correspondingly, female wrestlers execute more actions in the ground positions (29.3%) compared to male wrestlers (18.3%). The total number of actions performed is higher for male wrestlers (579) than for female wrestlers (518). Female wrestlers achieve more premature victories (32.7% of all matches) compared to male wrestlers (24.6%). The obtained results will assist coaches in better adapting to gender differences and developing specific training programs for athletes.
Improving Students' Mathematical Reasoning Ability and Self-Efficacy Based on DNR-Based Instruction
Authors: Maryono Iyon , Kusumah Yaya Sukjaya , Dahlan Jarnawi A. , Sunandar Sunandar , Jihad Asep
Published: December 2023

Kemampuan Penalaran Matematis (KPM) dan efikasi-diri sangat penting bagi mahasiswa calon guru matematika. Namun, fakta menjunjukkan bahwa dua hal tersebut belum sesuai dengan harapan.  Tujuan penelitian ini adalah untuk menganalisis dampak dari model DNR-based Instructions terhadap KPM dan efikasi-diri mahasiswa. Metode eksperimen semu digunakan pada penelitian ini dengan nonequivalent control group design. Sampel penelitian ini terdiri dari 39 mahasiswa kelompok model DNR-based Instructions dan 39 mahasiswa kelompok model konvensional. Penelitian ini menggunakan instrumen tes-KPM dengan validitas tinggi dan angket efikasi-diri. Hasil penelitian menunjukkan bahwa: KPM  mahasiswa kelompok model DNR-based Instructions lebih baik dari pada KPM  mahasiswa kelompok model konvensional, ditinjau secara keseluruhan maupun berdasarkan Pengetahuan Awal Matematis (PAM); Efikasi-diri mahasiswa kelompok model DNR-based Instructions berada pada kategori baik. Implikasi dari hasil penelitian ini adalah KPM dan efikasi-diri dapat ditingkatkan melalui aktivitas pembelajaran yang didasarkan pada cara memahami dan cara berpikir, kebutuhan intelektual dan penalaran berulang. Mathematical Reasoning Ability (MRA) and self-efficacy are very important for prospective mathematics teacher students. However, the facts show that these two things have not met expectations. The aim of this research is to analyze the impact of the DNR-based Instructions model on MRA and student self-efficacy. The quasi-experimental method was used in this research with a nonequivalent control group design. The sample for this study consisted of 39 students from the DNR-based Instructions model group and 39 students from the conventional model group. This research has used MRA-test instruments with high validity and self-efficacy questionnaires. The research results show that: MRA for students in the DNR-based Instructions model group is better than MRA for students in the conventional model group, both overall and based on Prior Mathematics Knowledge (PMK); The self-efficacy of students in the DNR-based Instructions model group is in the good category. The implication of the results of this research is that MRA and self-efficacy can be improved through learning activities that are based on ways of understanding and ways of thinking, intellectual needs and repetitive reasoning.
Cognitive Flexibility in Developing Higher-Order Thinking Skills in the Course of Ring Theory
Authors: Nuraida Ida , Sugilar Hamdan
Published: December 2023

Mata kuliah Teori Ring merupakan salah satu mata kuliah bidang matematika yang cukup ketat dalam memberlakukan sistem deduktif-aksiomatik, namun mahasiswa kesulitan memecahkan masalah karena kurang bisa berpikir secara fleksibel saat menerima informasi baru. Tujuan penelitian ini adalah untuk mengetahui hubungan antara cognitive flexibility dengan keterampilan berpikir tingkat tinggi atau Higher-Order Thinking Skills (HOTS). Metode penelitian yang digunakan adalah korelasional Ex Pose Facto. Penelitian dilakukan di Prodi Pendidikan Matematika UIN Sunan Gunung Djati Bandung dengan jumlah mahasiswa yang diteliti sebanyak 120 orang sebesar 1,2%. Teknik analisis data yang digunakan adalah uji regresi linier sederhana. Berdasarkan hasil penelitian dapat disimpulkan bahwa Cognitive Flexibility memiliki pengaruh positif terhadap kemampuan berpikir tingkat tinggi sebesar . Pengaruh positif ini bermakna semakin meningkatnya Cognitive Flexibility mahasiswa maka akan berpengaruh terhadap peningkatan Kemampuan Berpikir Tingkat Tinggi mahasiswa, sehingga akan memberikan impact pada kemampuan yang dihasilkan dari keterampilan mengerjakan soal HOTS terhadap kemampuan fleksibilitas kognitif yang pada akhirnya terwujud sebuah produk manusia yang siap menghadapi tantangan kompleksitas masalah. The Ring Theory course is one of the mathematics courses that are quite strict in applying deductive-axiomatic systems, but students have difficulty solving problems because they are less able to think flexibly when receiving new information. This study aimed to determine the relationship between cognitive flexibility and Higher-Order Thinking Skills (HOTS). The research method used is correlational Ex Pose Facto. The research was conducted at the Mathematics Education UIN Sunan Gunung Djati Bandung with the number of students studying as many as 120 people amounting to 1.2%. The data analysis technique used is a simple linear regression test. Based on the study results, it can be concluded that Cognitive Flexibility positively influences higher-order thinking skills. This positive influence means that the increasing Cognitive Flexibility of students will affect the improvement of students' higher-order thinking skills, it will have an impact on the abilities resulting from the skills of doing HOTS  questions on the ability of cognitive flexibility which ultimately materializes a human product that is ready to face the challenges of problem complexity.
The Development of Problem Solving-Based Interactive Learning Media to Improve Mathematical Communication and Self-Regulated Skill
Authors: Sitanggang Mariani , Mulyono Mulyono , Saragih Sahat
Published: December 2023

Penelitian ini bertujuan untuk menghasilkan media pembelajaran interaktif valid, praktis, dan efektif yang dikembangkan melalui model Problem Based Learning, menganalisis peningkatan kemampuan komunikasi matematis dan self-regulated learning siswa dengan menggunakan media pembelajaran interakitf model Problem Based Learning, serta menganalisis proses jawaban siswa dalam menyelesaikan tes kemampuan komunikasi   matematis.   Penelitian   ini   merupakan   penelitian   pengembangan dengan menggunakan model 4D (Define, Design, Develop, Disseminate). Subjek penelitian ini adalah siswa kelas 8 SMP. Penelitian ini menghasilkan media pembelajaran interaktif yang berupa RPP, lembar kerja peserta didik, tes kemampuan komunikasi matematis siswa, dan angket self-regulated learning. Hasil penelitian ini menunjukkan bahwa media pembelajaran interaktif yang dikembangkan melalui model Problem Based Learning valid, praktis, dan interaktif, adanya peningkatan kemampuan komunikasi matematis dan self-regulated learning siswa menggunakan media pembelajaran interakitf melalui model Problem Based Learning, serta pada  proses jawaban, jenis kesalahan yang sering dilakukan siswa dalam menyelesaikan tes kemampuan komunikasi matematika adalah konsep, operasi perhitungan, dan prinsip. Berdasarkan hasil penelitian ini, peneliti menyarankan agar guru dapat menggunakan perangkat pembelajaran ini guna menumbuhkembangkan kemampuan komunikasi matematis matematis siswa. This research aims to produce valid, practical, and effective interactive learning media developed through the Problem Based Learning model, analyzing the increase in students' mathematical communication skills and self-regulated learning using interactive learning media using the Problem Based Learning model, also analyzing the process of students' answers in solving mathematical communication ability test. This research is development research using the 4D model (Define, Design, Develop, Disseminate). The subjects of this research were class VIII students of junior high school. This research produces interactive learning media in the form of lesson plans, student worksheets, tests of students' mathematical communication skills, and self-regulated learning questionnaires. The results of this research show that the interactive learning media developed through the Problem Based Learning model was valid, practically, and effectively, increased students' mathematical communication skills and self-regulated learning using interactive learning media through the Problem Based Learning model, also in the answer process, the types of errors that students often make in completing mathematical communication ability tests are concepts, calculation operations, and principles. Based on the results of this research, the researcher suggests that teachers can use this learning tool to develop students' mathematical communication skills.
Exploring disclaimers on Chinese social networking sites from a metapragmatic perspective
Authors: Li Chuanqi , Li Danli
Published: December 2023

This study explores the employment of disclaimers as metapragmatic devices in online interpersonal interaction on a Chinese social networking site, Weibo. Previous studies discussed meta-negation disclaimers and meta-prohibition disclaimers. This study establishes a new type of disclaimer: meta-condition disclaimers. It examines the forms and functions of the three types of disclaimers. Prior studies explained disclaimers as either prospective moves or retrospective moves. This study further introduces disclaimers as conjunctive moves, which bridge the speaker’s ongoing communicative behaviour. Also, it investigates the communicative purposes of using disclaimers, revealing that disclaimers are mainly employed by Chinese netizens to convey criticism. Furthermore, this research probes into the underlying cultural factors of employing disclaimers. It uncovers certain values ingrained in Chinese culture, such as ren (kindheartedness), yi (righteousness) and li (politeness). The study contributes to a global understanding of disclaimers and could provide some insights into online rapport management.
Evaluation of salivary alpha amylase activity in smokers with periodontitis, Khartoum state, 2023
Authors:   Chemical Pathology Department, Faculty of Medical Laboratory Sciences, University of Medical Sciences and Technology, Khartoum, Sudan, Allah Fatima Abd Alwhab Awad , Ahmed Hafsa Ahmed Elrheima ,   Chemical Pathology Department, Faculty of Medical Laboratory Sciences, University of Medical Sciences and Technology, Khartoum, Sudan
Published: December 2023

Introduction and aim. Smoking widely affect oral health, including its role in the development of periodontitis. Saliva contains an antioxidant system and various enzymes. The study was designed to evaluate the activity of salivary alpha amylase among individuals who smoke and have periodontitis. Material and methods. A total of 100 participants were included, with 50 cases (cigarette smokers with periodontitis) and the remaining 50 nonsmokers with healthy periodontium as the control group. Saliva samples were collected to measure salivary alpha amylase activity. Results. Smokers with periodontitis had significantly higher levels of salivary alpha amylase compared to the control group (177.96±14.5 vs 94.04±19.6 IU/mL, p<0.001). Additionally, there was a weak negative correlation between the level of alpha amylase and the age of the patients (p=0.01, r=0.376). However, no correlation was found between the level of alpha amylase and the duration of smoking (p=0.584, r=0.079). Conclusion. There is a significant increase in salivary alpha amylase levels among smokers with periodontitis. No correlation was found between age and salivary alpha amylase levels. However, a weak positive correlation was observed between the duration of smoking and salivary alpha amylase activity.
The effect of a physical therapy programme on the condition of upper limb muscles in patients with rheumatoid arthritis
Authors:   Department of Medical and Biological Disciplines, Institute of Health, National University of Water and Environmental Engineering, Rivne, Ukraine, Grygus Igor , Nogas Anzhela ,   Department of Medical and Biological Disciplines, Institute of Health, National University of Water and Environmental Engineering, Rivne, Ukraine
Published: December 2023

Introduction and aim. Rheumatoid arthritis is a chronic progressive systemic disease of the connective tissue affecting the joints, mainly small, of the erosive-destructive polyarthritis type, and frequent systemic inflammatory damage to internal organs. The purpose of the research is to evaluate the effectiveness of physical therapy on the muscles of upper limbs in patients with rheumatoid arthritis by the dynamics of muscle strength and strength index. Material and methods. To determine the strength of the muscles of the affected upper limbs were used dynamometry, calculated strength index as a percentage to assess the functional ability of the affected limb. All patients were divided into control (n=92) and main (n=96) groups, taking into account the functional insufficiency of the joints. Results. After 6 months of physical therapy, muscle strength indicators in the main group of patients with 1st degree of functional joints insufficiency (FJI) in the affected right limb increased by 3.1 kg, in the left by 3 kg; with 2nd degree FJI – in the right limb by 4.2 kg, in the left – by 3.7 kg, significantly exceeded the same indicators in patients of the control group (р<0.05). Similarly, there was an increase in the strength index in the patients of the main group. Conclusion. Physical therapy technology has been developed and implemented effectively influenced the increase in muscle strength and strength index of affected upper limbs of the main group of patients with rheumatoid arthritis.
A study on the mycobacterial burden and phenotypic drug resistance pattern with reference to the GeneXpert Cycle Threshold values in pulmonary tuberculosis
Authors:   Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India, Kashyap Bineeta , Sarkar Krishna ,   Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India, Singh Kapil ,   Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India, Hyanki Puneeta ,   DOTS Center, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India
Published: December 2023

Introduction and aim. Tuberculosis (TB) remains a significant global health challenge. Early and accurate diagnosis is crucial to prevent further transmission. The present study aimed to correlate cycle threshold values with smear microscopy and culture positivity, and determine cut-off cycle threshold values for levels of smear grade and culture positivity. Material and methods. Forty presumptive cases of pulmonary TB were included and subjected to Ziehl- Neelsen stain, culture on Lowenstein Jensen media, CBNAAT and drug susceptibility testing for first line anti-tubercular drugs. Results. Our study predicts 3+, 2+, and 1+ sputum smear grade at a cut-off of Ct value ≤ 16.74, ≤19.68, and ≤ 22.32 respectively. A strong positive correlation was found between time to culture positivity and Ct value. A cut-off of Ct value ≤22.32 predicts culture positivity with a sensitivity of 92%, and a specificity of 67%. None of the isolates showed rifampicin resistance by 1% proportion method. Conclusion. Understanding the appropriate utilization of CBNAAT Ct values and their correlation with smear microscopy grade, culture, and drug susceptibility testing can assist clinicians in early identification and prompt initiation of appropriate treatment. This knowledge can contribute to the prevention of drug resistance, reduced transmission, and a decreased disease burden associated with TB.
Genetic variants of the glucagon-like receptor-1 in obesity
Authors:   Department of Pediatrics 1 and Medical Genetics, Dnipro State Medical University, Dnipro, Ukraine, Nikulina Anna
Published: December 2023

Introduction and aim. Dysfunction of the glucagon-like peptide 1 (GLP-1)/GLP-1 receptor (GLP-1R) axis promotes obesity and metabolic disorders. The aim was to study the associations of the single nucleotide variants (SNV) GLP1R gene with proinflammatory cytokines and metabolic disorders in children with various obesity phenotypes. Material and methods. 252 children with obesity aged 6-18 years were examined. The first group (n=152) was represented by children with metabolically unhealthy obesity (MUO). The second group (n=100) consolidated of children with metabolically healthy obesity (MHO). Whole genome sequencing (CeGat, Germany) was performed in 52 children. Results. An association with the development of obesity was noted for T alleles rs61754624 (t=3.33) and rs10305457 (t=2.06); with MUO – for C alleles rs1042044 (t=2.23), rs1126476 (t=2.63), rs2235868 (t=2.82); T alleles rs61754624 (t=3.33), rs10305457 (t=2.06) GLP1R, p<0.05. In the MHO group, a correlation was found with the levels of pro-inflammatory markers IL-1β, IL-6 in the presence of the GA genotype SNV rs3765468; with hyperglycemia - GA genotype SNV rs6923761, CC genotype SNV rs1042044, AA rs6918287; hyperinsulinemia - GA genotype SNV rs3765468, GG rs10305421; triglyceridemia - AA rs6918287 of GLP1R. Conclusion. SNV rs1042044, rs3765468, rs6923761, s6918287, and rs rs10305421 GLP1R are associated with the development of MUO in individuals with MHO.
Haemocytometric profile and plasma levels of selected cytokines in patients at various stages of cervical cancer
Authors:   Department of Radiation Oncology, College of Medicine, University of Ibadan, Ibadan, Nigeria, Jimoh Mutiu Alani , Onifade Abdulfatah Adekunle ,   Department of Immunology, College of Medicine, University of Ibadan, Ibadan, Nigeria, Abbiyesuku Fayeofori Mpakaboari ,   Department of Chemical Pathology, Babcock University, Illishan-Remo, Ogun State, Nigeria, Edem Victory Fabian ,   Department of Immunology, College of Medicine, University of Ibadan, Ibadan, Nigeria, Rahamon Sheu Kadiri ,   Department of Immunology, College of Medicine, University of Ibadan, Ibadan, Nigeria, Arinola Olatunbosun Ganiyu ,   Department of Immunology, College of Medicine, University of Ibadan, Ibadan, Nigeria
Published: December 2023

Introduction and aim. Reports have shown that there is alteration in haematological and inflammatory processes in patients with cervical cancer. However, there is the dearth of information on the pattern of alteration in Nigerian patients with cervical cancer at various stages of the disease. Therefore, haemocytometric profile and plasma levels of interleukin-6 (IL-6) and IL-12 were determined in Nigerian patients with cervical cancer at various stages of the disease. Material and methods. Eighty-nine adults consisting of 49 patients with cervical cancer and 40 apparently healthy controls were enrolled into this study. Haemocytometric profile was determined using automated haematology analyzer while the plasma levels of interleukin-6 (IL-6) and IL-12 were determined using ELISA. Results. Of the participants with cervical cancer, 6.12%, 24.49%, 53.06% and 16.33% were in stages I, II, III and IV respectively. The mean plasma IL-6 level was significantly higher in patients at stage IV of the cancer compared with those in stages I, II and III. No significant differences were observed in the mean plasma IL-12 level, and the haemocytometric profile when patients in different stages of the cancer were compared with one another. Plasma IL-6 had significant positive correlation with the lymphocytes count and cancer stage but had significant negative correlation with packed cell volume (PCV), haemoglobin and total white blood cells count (WBC) in patients with cervical cancer. Conclusion. Interleukin-6 appears to play an important role in the progression of cervical cancer and could be involved in cervical cancer-associated alteration in haemocytometric profile.
The investigation of the impact of education on sexual health/reproductive health knowledge levels of nurses and midwives in extraordinary situations – evidence from Turkey
Authors:   Department of Nursing, Faculty of Health Sciences, Bartin University, Bartin, Turkey, Cirban Ekrem Ebru , Kuş Tuğçe ,   Department of Nursing, Faculty of Health Sciences, Bartin University, Bartin, Turkey, Erkmen Emir ,   Department of Nursing, Faculty of Health Sciences, Bartin University, Bartin, Turkey, Dursun Nisanur ,   Department of Nursing, Faculty of Health Sciences, Bartin University, Bartin, Turkey
Published: December 2023

Introduction and aim. In extraordinary situations, sexual/reproductive health services are very important for the health of the whole society, especially women and children. The aim of this study is to assess the impact of training provided on sexual health/reproductive health during extraordinary situations on the knowledge levels of nurses and midwives. Material and methods. The research was conducted using a single-group pre-test-post-test follow-up test measurement quasi-experimental design. It was completed between November 2021–June 2022 with 140 participants working in a province in Turkey. The data were collected with the “Descriptive Information Form” and the “Sexual Health and Reproductive Health Knowledge Assessment Form for Extraordinary Situations”. Training was given with the Sexual Health/Reproductive Health Training Booklet for Extraordinary Situations. Results. It was found that the participants scored 20.82±4.47 on the Sexual Health and Reproductive Health Knowledge Assessment Form for Extraordinary Situations in the pre-test, 27.63±2.67 in the post-test, and 27.07±3.46 in the follow-up test. As a result of the training, it was determined that the difference between the scores they got from the Sexual Health and Reproductive Health Knowledge Assessment Form for Extraordinary Situations was due to the pre-test (p<0.05). Conclusion. In the study, the participants scored above the average in the pre-test, while they achieved significantly higher scores in the post-test and follow-up test. This shows that the training given to nurses and midwives is effective.
The gut microbiota in development and treatment of depression
Authors:   Student Research Group at the Chair and Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, Lublin, Poland, Wilczek Natalia , Bogucka Julia ,   Students’ Scientific Association at the Chair and Department of Epidemiology, Medical University of Lublin, Lublin, Poland, Brzyska Anna ,   Students’ Scientific Association at the Chair and Department of Epidemiology, Medical University of Lublin, Lublin, Poland, Sielwanowska Wiktoria ,   Student Research Group at the Chair and Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, Lublin, Poland, Syzdoł Bartłomiej ,   Department of Child Neurology, Medical University of Lublin, Lublin, Poland, Piecewicz-Szczęsna Halina ,   Chair and Department of Epidemiology, Medical University of Lublin, Lublin, Poland
Published: December 2023

Introduction and aim. Nowadays, almost 4% of people in the world suffer from depressive disorders, and the forecasts of further increase in incidence are alarming. The disease is debilitating and can lead to suicide, and available treatments are still imperfect. The aim of the study was to review the literature and present the potential role of the gut microbiota in the development of depression and to consider the use of prebiotics and probiotics as one of the therapeutic options in this disease. Material and methods. Review of articles published on PubMed since 2015. Analysis of the literature. The available reports point to a relationship between disturbances in the composition of the intestinal flora and the development of depressive disorders. In addition, more and more studies indicate the benefits of the influence on mood and clinical improvement, observed when using psychobiotics as an adjuvant treatment of depression, as well as monotherapy. Conclusion. Further research is needed in this area, especially in humans, to gain a deeper understanding of the role of the gut microbiota in depression and the promising use of psychobiotics for its treatment.
Determination of attitudes and practices of nurses working in the psychiatry clinic towards physical health care of individuals with severe mental illness
Authors:   Elazığ Mental Health and Diseases Hospital, Elazığ, Turkey, Kurtoğlu Hande Yardımcı , Çelik İnce Sevecen ,   Faculty of Health Science, Psychiatric Nursing Department, Zonguldak Bülent Ecevit University, Zonguldak, Turkey
Published: December 2023

Introduction and aim. Individuals with severe mental illness experience more physical health problems than the general population and their life expectancy may be shorter. Therefore, the physical care provided to these patients is very important.This study aims to examine the attitudes, practices, and training needs of nurses working in psychiatry clinics towards physical health care of individuals with severe mental illness. Material and methods. This descriptive, cross-sectional study collected data from 139 nurses in psychiatry clinics using the Personal Information Form and Physical Health Attitude Scale. Results. This study found that nurses often provide physical healthcare as part of their routine care for individuals with severe mental illness. However, the study also revealed that nurses require additional education to better provide this type of care. Despite this, the nurses generally displayed a positive attitude towards physical health. The average total score on the physical health attitude scale was 80.33±10.14. Conclusion. The study concluded that nurses have a positive attitude towards physical health in general. The role of nurses working in psychiatry clinics is crucial in evaluating and caring for physical health of individuals with severe mental illness, as it is an important aspect of holistic nursing care. It is necessary to make nurses aware of their shortcomings in providing physical health care and support them in improving in this area.
Utilizing machine learning to create a blood-based scoring system for sepsis detection
Authors:   Leigh High School, San Jose, United States, Aref Sadik
Published: December 2023

Introduction and aim. Sepsis, a disease caused by inflammation as a response to infection, often goes undiagnosed due to its heterogeneity and lack of a single diagnostic test. Current sepsis detection scoring systems have low sensitivity and utilize biomarkers that are difficult to obtain from a single test. The goal of this research is to create a scoring system that outperforms current industry standards by utilizing blood-based biomarkers readily available in hospital settings. Material and methods. Machine learning algorithms were run through Google Colab using Extreme Gradient Boost classifier. The dataset was obtained from NCBI website containing electronic hospital records of intensive care patients. A multivariate linear regression was applied to the dataset to determine statistically significant biomarkers in the detection of sepsis, and their β coefficients. Then, validation testing was performed, and the performance was compared to other scoring systems. Results. This experiment reveals that a sepsis detection system that utilizes procalcitonin, white blood cells, C-reactive protein, neutrophil to lymphocyte ratio, and albumin can outperform other biomarkers and scoring systems with high sensitivity at a recall score of 0.7922. Conclusion. These results demonstrate the potential of utilizing a blood-based scoring system for sepsis detection within hospital settings.
Percutaneous sclerotherapy using polidocanol in the treatment of aneurysmal bone cysts of extremities – a report of 28 consecutive cases
Authors:   Department of Orthopedics, SMS Medical College, Jaipur, Rajasthan, India, Harshwal Raj Kumar , Kumawat Kaushal Kishore ,   Department of Orthopedics, SMS Medical College, Jaipur, Rajasthan, India, Saini Narender ,   Department of Orthopedics, SMS Medical College, Jaipur, Rajasthan, India, Sehrawat Manisha ,   Department of Orthopedics, SMS Medical College, Jaipur, Rajasthan, India, Meena Devi Sahay ,   Department of Orthopedics, SMS Medical College, Jaipur, Rajasthan, India
Published: December 2023

Introduction and aim. Aneurysmal bone cysts (ABC) are aggressive benign lesions with high rates of recurrence rendering its treatment uniquely challenging. We report the outcome in 28 consecutive patients of ABC of extremities treated with percutaneus sclerotherapy using 3% polidocanol over a period of 5 years. Material and methods. In biopsy proven 28 ABC cases, Injection polidocanol 3% was used as sclerosing agent under fluoroscopy guidance. Injections were repeated at 6-week intervals till complete healing of cysts. Radiological and functional results were assessed by Rastogi et al. criteria, VAS score and Enneking scoring method. Results. 25 out of 26 patients (89.28%) displayed good clinical response with an average 2.56 injections per patients. The mean follow-up period was 17.04±7.08 months. Reduction in cyst volume (mean 6.86±1.48 to 0.71±1.48.) and VAS score (mean 6.72±1.51 to 0.56±1.08) and improvement in Enneking score (17.35±3.14 to 28.92±1.35) at last follow up was significant. No recurrence was reported during the study period. Treatment failure, skin sclerosis and infection were reported in one case each. Conclusion. sclerotherapy with polidocanol 3% for primary ABC is safe and effective alternate method with advantage of no surgical morbidity, having better functional score with lesser recurrence and minimal complications.
Speech development delay in autism spectrum disorder – the perspective of using the “Talk To Me” speech therapy application
Authors:   Clinical Hospital No 2 in Rzeszow, Rzeszow, Poland, Warmbier Wojciech A. , Perenc Lidia ,   Institute of Health Sciences, Medical College of Rzeszow University, Rzeszow, Poland, Piwoński Paweł ,   Institute of Physiotherapy, Medical Faculty, University of Rzeszow, Rzeszów, Poland, Podgórska-Bednarz Justyna ,   Institute of Health Sciences, Medical College of Rzeszów University, Rzeszów, Poland
Published: December 2023

Introduction and aim. The paper aims to present the prospects of using the „Talk To Me” application in the case of a child with this neurodevelopmental disorder. Description of the case. The subject of the study was a 53-month-old boy who did not communicate verbally, but behaved forcefully. A child underwent a speech therapy using the „Talk To Me” application for a period of 12 weeks. The scale of acquiring language skills in the field of communication competence was used to monitor the progress of therapy. In the analyzed period, a decrease in the score on the scale from 23 to 15 points was observed, which means a result indicating an improvement in the communication sphere. The use of a newly developed therapeutic tool was an important motivational factor and, in the opinion of the boy’s mother, significantly influenced the progress in therapy, which had not been observed before using a conventional approach. Conclusion. The „Talk To Me” application is a therapeutic tool with potential effectiveness in the case of speech delays in children with autism spectrum disorder, and it is also compatible with behavioral therapy, a widely used therapeutic method with proven effectiveness in autism spectrum disorder.