bluuebunny/crossref_metadata_2025 huggingface dataset:
Agronomical Practices and Management for Commercial Cultivation of Portulaca oleracea as a Crop: A Review
Authors: Carrascosa Angel , Pascual Jose Antonio , Ros Margarita , Petropoulos Spyridon A. , Alguacil Maria del Mar
Published: March 2023

Soil is an essential resource, and its degradation is challenging modern agriculture, while its impact is expected to increase in the near future. One of the strategies to address this issue is to incorporate new alternative crops able to tolerate arduous conditions, as well as for the use of sustainable agricultural practices in order to recover and/or improve soil health. Additionally, the increasing market for new functional/healthy natural foods promotes the search for potential alternative crop species with promising bioactive compounds content. For this purpose, wild edible plants are a key option because they have already been consumed for hundreds of years in traditional gastronomy and there is well-established evidence of their health-promoting effects. Moreover, since they are not a cultivated species, they are able to grow under natural conditions without human intervention. Among them, common purslane is an interesting wild edible species and a good candidate for integration in commercial farming systems. With worldwide spread, it is able to tolerate drought, salinity and heat stress and is already used in traditional dishes, while it is highly appreciated for its high nutritional value due to its bioactive compound content, especially omega-3 fatty acids. In this review, we aim to present the breeding and cultivation practices of purslane, as well as the effects of abiotic stressors on yield and chemical composition of the edible parts. Finally, we present information that helps to optimize purslane cultivation and facilitate its management in degraded soils for their exploitation in the existing farming systems.
Plant Species’ Capacity for Range Shifts at the Habitat and Geographic Scales: A Trade-Off-Based Framework
Authors: McNichol Bailey H. , Russo Sabrina E.
Published: March 2023

Climate change is causing rapid shifts in the abiotic and biotic environmental conditions experienced by plant populations, but we lack generalizable frameworks for predicting the consequences for species. These changes may cause individuals to become poorly matched to their environments, potentially inducing shifts in the distributions of populations and altering species’ habitat and geographic ranges. We present a trade-off-based framework for understanding and predicting whether plant species may undergo range shifts, based on ecological strategies defined by functional trait variation. We define a species’ capacity for undergoing range shifts as the product of its colonization ability and the ability to express a phenotype well-suited to the environment across life stages (phenotype–environment matching), which are both strongly influenced by a species’ ecological strategy and unavoidable trade-offs in function. While numerous strategies may be successful in an environment, severe phenotype–environment mismatches result in habitat filtering: propagules reach a site but cannot establish there. Operating within individuals and populations, these processes will affect species’ habitat ranges at small scales, and aggregated across populations, will determine whether species track climatic changes and undergo geographic range shifts. This trade-off-based framework can provide a conceptual basis for species distribution models that are generalizable across plant species, aiding in the prediction of shifts in plant species’ ranges in response to climate change.
Genome-Wide Identification and Expression Analysis of NPF Genes in Cucumber (Cucumis sativus L.)
Authors: Zhang Mengying , Zhang Wenyan , Zheng Zijian , Zhang Zhiping , Hua Bing , Liu Jiexia , Miao Minmin
Published: March 2023

The NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER family (NPF) proteins perform an essential role in regulating plant nitrate absorption and distribution and in improving plant nitrogen use efficiency. In this study, cucumber (Cucumis sativus L.) NPF genes were comprehensively analyzed at the whole genome level, and 54 NPF genes were found to be unevenly distributed on seven chromosomes in the cucumber genome. The phylogenetic analysis showed that these genes could be divided into eight subfamilies. We renamed all CsNPF genes according to the international nomenclature, based on their homology with AtNPF genes. By surveying the expression profiles of CsNPF genes in various tissues, we found that CsNPF6.4 was specifically expressed in roots, indicating that CsNPF6.4 may play a role in N absorption; CsNPF6.3 was highly expressed in petioles, which may be related to NO3− storage in petioles; and CsNPF2.8 was highly expressed in fruits, which may promote NO3− transport to the embryos. We further examined their expression patterns under different abiotic stress and nitrogen conditions, and found that CsNPF7.2 and CsNPF7.3 responded to salt, cold, and low nitrogen stress. Taken together, our study lays a foundation for further exploration of the molecular and physiological functions of cucumber nitrate transporters.
Comparison of In Vitro Antimelanoma and Antimicrobial Activity of 2,3-Indolo-betulinic Acid and Its Glycine Conjugates
Authors: Lombrea Adelina , Semenescu Alexandra-Denisa , Magyari-Pavel Ioana Zinuca , Turks Māris , Lugiņina Jevgeņija , Peipiņš Uldis , Muntean Delia , Dehelean Cristina Adriana , Dinu Stefania , Danciu Corina
Published: March 2023

Malignant melanoma is one of the most pressing problems in the developing world. New therapeutic agents that might be effective in treating malignancies that have developed resistance to conventional medications are urgently required. Semisynthesis is an essential method for improving the biological activity and the therapeutic efficacy of natural product precursors. Semisynthetic derivatives of natural compounds are valuable sources of new drug candidates with a variety of pharmacological actions, including anticancer ones. Two novel semisynthetic derivatives of betulinic acid—N-(2,3-indolo-betulinoyl)diglycylglycine (BA1) and N-(2,3-indolo-betulinoyl)glycylglycine (BA2)—were designed and their antiproliferative, cytotoxic, and anti-migratory activity against A375 human melanoma cells was determined in comparison with known N-(2,3-indolo-betulinoyl)glycine (BA3), 2,3-indolo-betulinic acid (BA4) and naturally occurring betulinic acid (BI). A dose-dependent antiproliferative effect with IC50 values that ranged from 5.7 to 19.6 µM was observed in the series of all five compounds including betulinic acid. The novel compounds BA1 (IC50 = 5.7 µM) and BA2 (IC50 = 10.0 µM) were three times and two times more active than the parent cyclic structure B4 and natural BI. Additionally, compounds BA2, BA3, and BA4 possess antibacterial activity against Streptococcus pyogenes ATCC 19615 and Staphylococcus aureus ATCC 25923 with MIC values in the range of 13–16 µg/mL and 26–32 µg/mL, respectively. On the other hand, antifungal activity toward Candida albicans ATCC 10231 and Candida parapsilosis ATCC 22019 was found for compound BA3 with MIC 29 µg/mL. This is the first report of antibacterial and antifungal activity of 2,3-indolo-betulinic acid derivatives and also the first extended report on their anti-melanoma activity, which among others includes data on anti-migratory activity and shows the significance of amino acid side chain on the observed activity. The obtained data justify further research on the anti-melanoma and antimicrobial activity of 2,3-indolo-betulinic acid derivatives.
Medicinal Uses of the Fabaceae Family in Zimbabwe: A Review
Authors: Maroyi Alfred
Published: March 2023

The current study is aimed at providing a systematic review of the ethnomedicinal, phytochemical and pharmacological properties of Fabaceae species used as sources of traditional medicinies in Zimbabwe. Fabaceae is one of the well-known plant families of ethnopharmacological importance. Of the approximately 665 species of the Fabaceae family occurring in Zimbabwe, about 101 are used for medicinal purposes. Many communities in the country, mainly in peri-urban, rural and marginalized areas with limited access to healthcare facilities, rely on traditional medicines as their primary healthcare. The study reviewed research studies undertaken on Zimbabwe’s Fabaceae species during 1959 to 2022. Information was gathered from literature sourced from Google Scholar, Science Direct, Scopus, PubMed, books, dissertations, theses and scientific reports. This study showed that 101 species are traditionally used to manage human and animal diseases in Zimbabwe. The genera with the highest number of medicinal uses are Indigofera, Senna, Albizia, Rhynchosia and Vachellia. Species of these genera are used as traditional medicines against 134 medical conditions, mainly gastrointestinal conditions, female reproductive conditions, respiratory conditions and sexually transmitted infections. Shrubs (39.0%), trees (37.0%) and herbs (18.0%) are the primary sources of traditional medicines, while roots (80.2%), leaves (36.6%), bark (27.7%) and fruits (8.9%) are the most widely used plant parts. Many of Zimbabwe’s Fabaceae species used as sources of traditional medicines have been assessed for their phytochemical and pharmacological properties, corroborating their medicinal uses. However, there is a need to unravel the therapeutic potential of the family through further ethnopharmacological research focusing on toxicological studies, in vitro and in vivo models, biochemical assays and pharmacokinetic studies.
Nitric Oxide and Proline Modulate Redox Homeostasis and Photosynthetic Metabolism in Wheat Plants under High Temperature Stress Acclimation
Authors: Sehar Zebus , Mir Iqbal R. , Khan Sheen , Masood Asim , Khan Nafees A.
Published: March 2023

The effects of exogenously-sourced NO (nitric oxide, as 100 µM SNP) and proline (50 mM) in the protection of the photosynthetic performance of wheat (Triticum aestivum L.) plants against heat stress were investigated. The study focused on the mechanisms of proline accumulation, activity, gene expression of antioxidant enzymes, and NO generation. Plants were exposed to a temperature of 40 °C for 6 h per day over 15 days, then allowed to recover at 28 °C. Heat-stressed plants showed increased oxidative stress, with higher levels of H2O2 and TBARS (thiobarbituric acid reactive substances) and increased proline accumulation, ACS activity, ethylene evolution, and NO generation, which in turn leads to increased accumulation of antioxidant enzymes and reduced photosynthetic attributes. In the tested wheat cultivar, the exogenous application of SNP and proline under heat stress improved the photosynthesis and reduced oxidative stress by enhancing the enzymatic antioxidant defense system. Potentially, the promoter AOX (alternative oxidase) played a role in maintaining redox homeostasis by lowering H2O2 and TBARS levels. The genes for GR antioxidant and photosystem II core protein encoding psbA and psbB were highly up-regulated in nitric oxide and proline treated heat-stressed plants, indicating that ethylene positively impacted photosynthesis under high temperature stress. Moreover, nitric oxide supplementation under high temperature stress optimized ethylene levels to regulate the assimilation and metabolism of proline and the antioxidant system, lowering the adverse effects. The study showed that nitric oxide and proline increased high temperature stress tolerance in wheat by increasing the osmolytes accumulation and the antioxidant system, resulting in enhanced photosynthesis.
Accumulation of Toxic Arsenic by Cherry Radish Tuber (Raphanus sativus var. sativus Pers.) and Its Physiological, Metabolic and Anatomical Stress Responses
Authors: Pavlíková Daniela , Pavlík Milan , Zemanová Veronika , Novák Milan , Doležal Petr , Dobrev Petre I. , Motyka Václav , Kraus Kamil
Published: March 2023

In a pot experiment, cherry radish (Raphanus sativus var. sativus Pers. ‘Viola’) was cultivated under two levels of As soil contamination—20 and 100 mg/kg. The increasing As content in tubers with increasing soil contamination led to changes in free amino acids (AAs) and phytohormone metabolism and antioxidative metabolites. Changes were mainly observed under conditions of high As contamination (As100). The content of indole-3-acetic acid in tubers varied under different levels of As stress, but As100 contamination led to an increase in its bacterial precursor indole-3-acetamide. A decrease in cis-zeatin-9-riboside-5′-monophosphate content and an increase in jasmonic acid content were found in this treatment. The free AA content in tubers was also reduced. The main free AAs were determined to be transport AAs (glutamate—Glu, aspartate, glutamine—Gln, asparagine) with the main portion being Gln. The Glu/Gln ratio—a significant indicator of primary N assimilation in plants—decreased under the As100 treatment condition. A decrease in antioxidative metabolite content—namely that of ascorbic acid and anthocyanins—was observed in this experiment. A decline in anthocyanin content is related to a decrease in aromatic AA content which is crucial for secondary metabolite production. The changes in tubers caused by As contamination were reflected in anatomical changes in the radish tubers and roots.
Increased Enzyme Loading in PICsomes via Controlling Membrane Permeability Improves Enzyme Prodrug Cancer Therapy Outcome
Authors: Goto Akinori , Anraku Yasutaka , Fukushima Shigeto , Kishimura Akihiro
Published: March 2023

Mesoscopic-sized polyion complex vesicles (PICsomes) with semi-permeable membranes are promising nanoreactors for enzyme prodrug therapy (EPT), mainly due to their ability to accommodate enzymes in their inner cavity. Increased loading efficacy and retained activity of enzymes in PICsomes are crucial for their practical application. Herein, a novel preparation method for enzyme-loaded PICsomes, the stepwise crosslinking (SWCL) method, was developed to achieve both high feed-to-loading enzyme efficiency and high enzymatic activity under in vivo conditions. Cytosine deaminase (CD), which catalyzes the conversion of the 5-fluorocytosine (5-FC) prodrug to cytotoxic 5-fluorouracil (5-FU), was loaded into PICsomes. The SWCL strategy enabled a substantial increase in CD encapsulation efficiency, up to ~44% of the feeding amount. CD-loaded PICsomes (CD@PICsomes) showed prolonged blood circulation to achieve appreciable tumor accumulation via enhanced permeability and retention effect. The combination of CD@PICsomes and 5-FC produced superior antitumor activity in a subcutaneous model of C26 murine colon adenocarcinoma, even at a lower dose than systemic 5-FU treatment, and showed significantly reduced adverse effects. These results reveal the feasibility of PICsome-based EPT as a novel, highly efficient, and safe cancer treatment modality.
Bio-Polyethylene Composites Based on Sugar Cane and Curauá Fiber: An Experimental Study
Authors: Barbalho Gustavo Henrique de Almeida , Nascimento José Jefferson da Silva , Silva Lucineide Balbino da , Gomez Ricardo Soares , Farias Daniel Oliveira de , Diniz Diego David Silva , Santos Rosilda Sousa , Figueiredo Maria José de , Lima Antonio Gilson Barbosa de
Published: March 2023

For the purpose of renewable materials applications, Curauá fiber treated with 5% sodium hydroxide was added to high-density biopolyethylene, using an entirely Brazilian raw material of sugarcane ethanol. Polyethylene grafted with maleic anhydride was used as a compatibilizer. With the addition of curauá fiber, the crystallinity was reduced, possibly due to interactions in the crystalline matrix. A positive thermal resistance effect was observed for the maximum degradation temperatures of the biocomposites. When curauá fiber was added (5% by weight), the morphology showed interfacial adhesion, greater energy storage and damping capacity. Although curauá fiber additions did not affect the yield strength of high-density bio polyethylene, its fracture toughness improved. With the addition of curauá fiber (5% by weight), the fracture strain was greatly reduced to about 52%, the impact strength was also reduced, suggesting a reinforcing effect. Concomitantly, the modulus and the maximum bending stress, as well as the Shore D hardness of the curauá fiber biocomposites (at 3 and 5% by weight), were improved. Two important aspects of product viability were achieved. First, there was no change in processability and, second, with the addition of small amounts of curauá fiber, there was a gain in the specific properties of the biopolymer. The resulting synergies can help ensure more sustainable and environmentally friendly manufacturing of automotive products.
Bacterial Inhibition and Osteogenic Potentials of Sr/Zn Co-Doped Nano-Hydroxyapatite-PLGA Composite Scaffold for Bone Tissue Engineering Applications
Authors: Hassan Mozan , Khaleel Abbas , Karam Sherif Mohamed , Al-Marzouqi Ali Hassan , ur Rehman Ihtesham , Mohsin Sahar
Published: March 2023

Bacterial infection associated with bone grafts is one of the major challenges that can lead to implant failure. Treatment of these infections is a costly endeavor; therefore, an ideal bone scaffold should merge both biocompatibility and antibacterial activity. Antibiotic-impregnated scaffolds may prevent bacterial colonization but exacerbate the global antibiotic resistance problem. Recent approaches combined scaffolds with metal ions that have antimicrobial properties. In our study, a unique strontium/zinc (Sr/Zn) co-doped nanohydroxyapatite (nHAp) and Poly (lactic-co-glycolic acid) -(PLGA) composite scaffold was fabricated using a chemical precipitation method with different ratios of Sr/Zn ions (1%, 2.5%, and 4%). The scaffolds’ antibacterial activity against Staphylococcus aureus were evaluated by counting bacterial colony-forming unit (CFU) numbers after direct contact with the scaffolds. The results showed a dose-dependent reduction in CFU numbers as the Zn concentration increased, with 4% Zn showing the best antibacterial properties of all the Zn-containing scaffolds. PLGA incorporation in Sr/Zn-nHAp did not affect the Zn antibacterial activity and the 4% Sr/Zn-nHAp-PLGA scaffold showed a 99.7% bacterial growth inhibition. MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) cell viability assay showed that Sr/Zn co-doping supported osteoblast cell proliferation with no apparent cytotoxicity and the highest doping percentage in the 4% Sr/Zn-nHAp-PLGA was found to be ideal for cell growth. In conclusion, these findings demonstrate the potential for a 4% Sr/Zn-nHAp-PLGA scaffold with enhanced antibacterial activity and cytocompatibility as a suitable candidate for bone regeneration.
Development of Multiwalled Carbon Nanotubes/Halloysite Nanotubes Reinforced Thermal Responsive Shape Memory Polymer Nanocomposites for Enhanced Mechanical and Shape Recovery Characteristics in 4D Printing Applications
Authors: Namathoti Sivanagaraju , Vakkalagadda Manikanta Ravindra Kumar
Published: March 2023

The mechanical and shape-recovery characteristics of 4D-printed thermally responsive shape-memory polyurethane (SMPU) reinforced with two types of reinforcements, multiwalled carbon nanotubes (MWCNTs) and Halloysite nanotubes (HNTs), are investigated in the present study. Three weight percentages of reinforcements (0, 0.5, and 1) in the SMPU matrix are considered, and the required composite specimens are obtained with 3D printing. Further, for the first time, the present study investigates the flexural test for multiple cycles to understand the 4D-printed specimens’ flexural behavior variation after shape recovery. The 1 wt% HNTS-reinforced specimen yielded higher tensile, flexural, and impact strengths. On the other hand, 1 wt% MWCNT-reinforced specimens exhibited quick shape recovery. Overall, enhanced mechanical properties were observed with HNT reinforcements, and a faster shape recovery was observed with MWCNT reinforcements. Further, the results are promising for the use of 4D-printed shape-memory polymer nanocomposites for repeated cycles even after a large bending deformation.
Performance Spectrum of Home-Compostable Biopolymer Fibers Compared to a Petrochemical Alternative
Authors: Schick Simon , Groten Robert , Seide Gunnar H.
Published: March 2023

Manufacturers of technical polymers must increasingly consider the degradability of their products due to the growing public interest in topics such as greenhouse gas emissions and microplastic pollution. Biobased polymers are part of the solution, but they are still more expensive and less well characterized than conventional petrochemical polymers. Therefore, few biobased polymers with technical applications have reached the market. Polylactic acid (PLA) is the most widely-used industrial thermoplastic biopolymer and is mainly found in the areas of packaging and single-use products. It is classed as biodegradable but only breaks down efficiently above the glass transition temperature of ~60 °C, so it persists in the environment. Some commercially available biobased polymers can break down under normal environmental conditions, including polybutylene succinate (PBS), polybutylene adipate terephthalate (PBAT) and thermoplastic starch (TPS), but they are used far less than PLA. This article compares polypropylene, a petrochemical polymer and benchmark for technical applications, with the commercially available biobased polymers PBS, PBAT and TPS, all of which are home-compostable. The comparison considers processing (using the same spinning equipment to generate comparable data) and utilization. Draw ratios ranged from 29 to 83, with take-up speeds from 450 to 1000 m/min. PP achieved benchmark tenacities over 50 cN/tex with these settings, while PBS and PBAT achieved over 10cN/tex. By comparing the performance of biopolymers to petrochemical polymers in the same melt-spinning setting, it is easier to decide which polymer to use in a particular application. This study shows the possibility that home-compostable biopolymers are suitable for products with lower mechanical properties. Only spinning the materials on the same machine with the same settings produces comparable data. This research, therefore, fills the niche and provides comparable data. To our knowledge, this report is the first direct comparison of polypropylene and biobased polymers in the same spinning process with the same parameter settings.
Crazing Initiation and Growth in Polymethyl Methacrylate under Effects of Alcohol and Stress
Authors: Yan Ying , Sun Yujia , Su Jiyang , Li Bo , Zhou Ping
Published: March 2023

Polymer crazing is typically a precursor to damage and considerably reduces the mechanical performance of polymer materials. The concentrated stress caused by machines and the solvent atmosphere created during machining exacerbates the formation of crazing. In this study, the tensile test method was employed to examine the initiation and progression of crazing. The research focused on polymethyl methacrylate (PMMA), both regular and oriented, and the impact of machining and alcohol solvents on the formation of crazing. The results showed that the alcohol solvent influenced PMMA through physical diffusion, whereas machining primarily affected crazing growth via residual stress. Treatment reduced the crazing stress threshold of PMMA from 20% to 35% and produced a threefold increase in its sensitivity to stress. The findings revealed that oriented PMMA exhibited 20 MPa higher resistance to crazing stress compared with regular PMMA. The results also indicated that the extension of the crazing tip and thickening were in conflict, with the crazing tip of regular PMMA severely bending under tensile stress. This study provides valuable insight into the initiation of crazing and the methods of its prevention.
A Review of Electrospun Nanofiber Interleaves for Interlaminar Toughening of Composite Laminates
Authors: Mahato Biltu , Lomov Stepan V. , Shiverskii Aleksei , Owais Mohammad , Abaimov Sergey G.
Published: March 2023

Recently, polymeric nanofiber veils have gained lot of interest for various industrial and research applications. Embedding polymeric veils has proven to be one of the most effective ways to prevent delamination caused by the poor out-of-plane properties of composite laminates. The polymeric veils are introduced between plies of a composite laminate, and their targeted effects on delamination initiation and propagation have been widely studied. This paper presents an overview of the application of nanofiber polymeric veils as toughening interleaves in fiber-reinforced composite laminates. It presents a systematic comparative analysis and summary of attainable fracture toughness improvements based on electrospun veil materials. Both Mode I and Mode II tests are covered. Various popular veil materials and their modifications are considered. The toughening mechanisms introduced by polymeric veils are identified, listed, and analyzed. The numerical modeling of failure in Mode I and Mode II delamination is also discussed. This analytical review can be used as guidance for veil material selection, for estimation of the achievable toughening effect, for understanding the toughening mechanism introduced by veils, and for the numerical modeling of delamination.
Fabrication of Rigid Isocyanate-Based Polyimide Foam Achieved Excellent Use Safety via Synergy between Expandable Graphite and Phosphorus-Containing Polyol
Authors: Zhang Junhe , Liu Yingze , Fu Xin , Wang Ting , Sun Gaohui , Zhang Xu , Han Shihui
Published: March 2023

For the advantages of low cost, excellent thermal insulation, and sound absorption properties, the rigid isocyanate-based polyimide foam (RPIF) presents great application prospects as a building insulation material. However, its inflammability and the accompanying toxic fumes create huge safety hazard. In this paper, reactive phosphate-containing polyol (PPCP) is synthesized and employed with expandable graphite (EG) to obtain RPIF with excellent use safety. EG can be considered as an ideal partner for PPCP to weaken the drawbacks in toxic fume release. Limiting oxygen index (LOI), cone calorimeter test (CCT), and toxic gas results show that the combination of PPCP and EG can synergistically enhance flame retardancy and the use safety of RPIF owing to the unique structure of a dense char layer possessing a flame barrier and toxic gas adsorption effects. When EG and PPCP are simultaneously applied to the RPIF system, the higher EG dosage will bring higher positive synergistic effects in the use safety of RPIF. The most preferred ratio of EG and PPCP is 2:1 (RPIF-10-5) in this study; RPIF-10-5 shows the highest LOI, low CCT results and specific optical density of smoke, and low HCN concentration. This design and the findings are of great significance to improving the application of RPIF.
Partial Miscibility and Concentration Distribution of Two-Phase Blends of Crosslinked NBR and PVC
Authors: Komori Yuka , Taniguchi Aoi , Shibata Haruhisa , Goto Shinya , Saito Hiromu
Published: March 2023

We found that the blends of nitrile butadiene rubber (NBR) and polyvinyl chloride (PVC) exhibited lower critical solution temperature (LCST)-type phase behavior in which a single-phase blend tends to phase separate at elevated temperatures when the acrylonitrile content of NBR was 29.0%. The tan δ peaks, which originated from the glass transitions of the component polymers measured by dynamic mechanical analysis (DMA), were largely shifted and broader in the blends when the blends were melted in the two-phase region of the LCST-type phase diagram, suggesting that NBR and PVC are partially miscible in the two-phase structure. The TEM-EDS elemental mapping analysis using a dual silicon drift detector revealed that each component polymer existed in the partner polymer-rich phase, and the PVC-rich domains consisted of aggregated small PVC particles the size of several ten nanometers. The partial miscibility of the blends was explained by the lever rule for the concentration distribution in the two-phase region of the LCST-type phase diagram.
Strain and Pressure Sensors Based on MWCNT/PDMS for Human Motion/Perception Detection
Authors: Zhao Xin , Mei Dong , Tang Gangqiang , Zhao Chun , Wang Jianfeng , Luo Minzhou , Li Lijie , Wang Yanjie
Published: March 2023

Flexible wearable devices have attracted wide attention in capacious fields because of their real-time and continuous monitoring of human information. The development of flexible sensors and corresponding integration with wearable devices is of great significance to build smart wearable devices. In this work, multi-walled carbon nanotube/polydimethylsiloxane-based (MWCNT/PDMS) resistive strain sensors and pressure sensors were developed to integrate a smart glove for human motion/perception detection. Firstly, MWCNT/PDMS conductive layers with excellent electrical and mechanical properties (resistivity of 2.897 KΩ · cm, elongation at break of 145%) were fabricated via a facile scraping-coating method. Then, a resistive strain sensor with a stable homogeneous structure was developed due to the similar physicochemical properties of the PDMS encapsulation layer and MWCNT/PDMS sensing layer. The resistance changes of the prepared strain sensor exhibited a great linear relationship with the strain. Moreover, it could output obvious repeatable dynamic response signals. It still had good cyclic stability and durability after 180° bending/restoring cycles and 40% stretching/releasing cycles. Secondly, MWCNT/PDMS layers with bioinspired spinous microstructures were formed by a simple sandpaper retransfer process and then assembled face-to-face into a resistive pressure sensor. The pressure sensor presented a linear relationship of relative resistance change and pressure in the range of 0–31.83 KPa with a sensitivity of 0.026 KPa−1, and a sensitivity of 2.769 × 10−4 KPa−1 over 32 KPa. Furthermore, it responded quickly and kept good cycle stability at 25.78 KPa dynamic loop over 2000 s. Finally, as parts of a wearable device, resistive strain sensors and a pressure sensor were then integrated into different areas of the glove. The cost-effective, multi-functional smart glove can recognize finger bending, gestures, and external mechanical stimuli, which holds great potential in the fields of medical healthcare, human-computer cooperation, and so on.
3D Printed Hydrogel Microneedle Arrays for Interstitial Fluid Biomarker Extraction and Colorimetric Detection
Authors: Razzaghi Mahmood , Seyfoori Amir , Pagan Erik , Askari Esfandyar , Hassani Najafabadi Alireza , Akbari Mohsen
Published: March 2023

To treat and manage chronic diseases, it is necessary to continuously monitor relevant biomarkers and modify treatment as the disease state changes. Compared to other bodily fluids, interstitial skin fluid (ISF) is a good choice for identifying biomarkers because it has a molecular composition most similar to blood plasma. Herein, a microneedle array (MNA) is presented to extract ISF painlessly and bloodlessly. The MNA is made of crosslinked poly(ethylene glycol) diacrylate (PEGDA), and an optimal balance of mechanical properties and absorption capability is suggested. Besides, the effect of needles’ cross-section shape on skin penetration is studied. The MNA is integrated with a multiplexed sensor that provides a color change in a biomarker concentration-dependent manner based on the relevant reactions for colorimetric detection of pH and glucose biomarkers. The developed device enables diagnosis by visual inspection or quantitative red, green, and blue (RGB) analysis. The outcomes of this study show that MNA can successfully identify biomarkers in interstitial skin fluid in a matter of minutes. The home-based long-term monitoring and management of metabolic diseases will benefit from such practical and self-administrable biomarker detection.
Effect of Adhesion Conditions on the Shear Bond Strength of 3D Printing Resins after Thermocycling Used for Definitive Prosthesis
Authors: Kang You-Jung , Park Yeseul , Shin Yooseok , Kim Jee-Hwan
Published: March 2023

Three-dimensional (3D) printing polymers such as urethane dimethacrylate (UDMA) and ethoxylated bisphenol A dimethacrylate (Bis-EMA) are typically used in definitive prosthesis and require surface treatments before bonding. However, surface treatment and adhesion conditions often affect long-term use. Herein, polymers were divided into Groups 1 and 2 for the UDMA and Bis-EMA components, respectively. The shear bond strength (SBS) between two types of 3D printing resins and resin cements was measured using Rely X Ultimate Cement and Rely X U200, according to adhesion conditions such as single bond universal (SBU) and airborne-particle abrasion (APA) treatments. Thermocycling was performed to evaluate the long-term stability. Sample surface changes were observed using a scanning electron microscope and surface roughness measuring instrument. The effect of interaction between the resin material and adhesion conditions on the SBS was analyzed via a two-way analysis of variance. The optimal adhesion condition for Group 1 was achieved when U200 was used after APA and SBU, whereas Group 2 was not significantly affected by the adhesion conditions. After thermocycling, the SBS significantly decreased in Group 1 without APA treatment and in the entire Group 2. Additionally, porosity, along with increased roughness, was observed on both material surfaces after APA.
Efficiency of Coagulation/Flocculation for the Removal of Complex Mixture of Textile Fibers from Water
Authors: Vasiljević Sanja , Vujić Maja , Agbaba Jasmina , Federici Stefania , Ducoli Serena , Tomić Radivoj , Tubić Aleksandra
Published: March 2023

Synthetic fibers enter wastewater treatment plants together with natural fibers, which may affect treatment efficiency, a fact not considered in previous studies. Therefore, the aim of the present study was to evaluate the efficiency of the coagulation/flocculation process for the removal of a mixture of textile fibers from different water matrices. Natural and synthetic fibers (100 mg/L; cotton, polyacrylonitrile, and polyamide) were added to a synthetic matrix, surface water and laundry wastewater and subjected to coagulation/flocculation experiments with ferric chloride (FeCl3) and polyaluminum chloride (PACl) under laboratory conditions. In the synthetic matrix, both coagulants were found to be effective, with FeCl3 having a lesser advantage, removing textile fibers almost completely from the water (up to 99% at a concentration of 3.94 mM). In surface water, all dosages had approximately similar high values, with the coagulant resulting in complete removal. In laundry effluent, the presence of surfactants is thought to affect coagulation efficiency. PACl was found to be effective in removing textile fibers from laundry wastewater, with the lowest removal efficiency being 89% and all dosages having similar removal efficiencies. Natural organic matter and bicarbonates showed a positive effect on the efficiency of FeCl3 in removing textile fibers from surface water. PACl showed better performance in coagulating laundry wastewater while surfactants had a negative effect on FeCl3 coagulation efficiency.
Goal-Oriented Tuning of Particle Filters for the Fault Diagnostics of Process Systems
Authors: Kenyeres Éva , Abonyi János
Published: March 2023

This study introduces particle filtering (PF) for the tracking and fault diagnostics of complex process systems. In process systems, model equations are often nonlinear and environmental noise is non-Gaussian. We propose a method for state estimation and fault detection in a wastewater treatment system. The contributions of the paper are the following: (1) A method is suggested for sensor placement based on the state estimation performance; (2) based on the sensitivity analysis of the particle filter parameters, a tuning method is proposed; (3) a case study is presented to compare the performances of the classical PF and intelligent particle filtering (IPF) algorithms; (4) for fault diagnostics purposes, bias and impact sensor faults were examined; moreover, the efficiency of fault detection was evaluated. The results verify that particle filtering is applicable and highly efficient for tracking and fault diagnostics tasks in process systems.
What about the Arsenic? Health Risk Assessment in Canned Tuna Commercialized in Northern Spain
Authors: Valiente-Diaz Carlos , del Valle Alejandra , Garcia-Vazquez Eva , Machado-Schiaffino Gonzalo , Ardura Alba
Published: March 2023

The incorrect labeling, as well as the bioaccumulation of heavy metals in seafood, represent a recurring problem worldwide, not only for natural resources but also for the consumers’ health. Heavy metals can be accumulated through the food chain and transferred to the final human consumer. Despite its toxicology, arsenic does not have a concentration limit on food, unlike other heavy metals like cadmium, mercury, and lead. Tuna species, with a worldwide distribution and high per capita consumption, represent a well-known toxicological issue caused by heavy metals. In this context, 80 samples of canned tuna were analyzed to check if the information contained in the label was correct and complete. Genetic identification was made by sequencing a fragment of 16S rDNA from 80 samples. For the heavy metal quantification, only those samples with the complete FAO fishing area information on the label were analyzed. Only 29 out of 80 samples presented enough information on the labels for the analysis. Some of the canned tuna commercialized in Spanish markets surpassed the safety standard levels established by the Joint FAO/WHO Expert Committee on Food Activities (JECFA) under the consumption rates of 300 g and 482 g per week. However, the carcinogenic risk (CRlim) for arsenic in all cans and all scenarios was higher than the safety levels.
Cannabis and Palliative Care Utilization among Non-Terminal Cancer Patients in the Illinois Medical Cannabis Program
Authors: Croker James A. , Bobitt Julie , Arora Kanika , Kaskie Brian
Published: March 2023

High-quality palliative care has been shown to provide benefits for cancer patients, including greater longevity when initiated earlier in treatment. Previous research conducted among terminal patients in the Illinois Medical Cannabis Program has suggested that cannabis may be used as a complement to palliative care and as an alternative to prescription opioid medications. However, there is little research exploring this phenomenon among non-terminal cancer patients receiving palliative care. In this study, we used primary cross-sectional survey data to (1) identify the factors associated with the utilization of palliative care, (2) examine the associations between the utilization of palliative care and self-reported improvements in physical and psychological symptoms, and (3) estimate the differences in the average 30-day pain levels for non-terminal cancer patients receiving palliative care who reported using opioids compared with other non-terminal cancer patients in palliative care who did not report using opioids. In our sample, 87 out of 542 (16%) non-terminal cancer patients were receiving palliative care, and of these 87 patients, 54 (62%) reported opioid use in the past 12 months. Non-terminal cancer patients in the sample who reported low psychological well-being, frequent gastrointestinal symptoms, and prescription opioid use in the past 12 months had greater odds of palliative care utilization. Palliative care utilization was also positively associated with self-reported improvements in gastrointestinal symptoms. The concurrent use of cannabis and prescription opioids was associated with higher average 30-day pain levels and with higher average pain levels at the initiation of cannabis use among those non-terminal cancer patients engaged in palliative care services.
Rethinking Jewish Theology
Authors: Oro Hershtein Lucas
Published: March 2023

This short essay takes an exploratory approach to redefining Jewish theology. I will offer a brief reflection on both possible philosophical—through the concepts of participation, truth, and textuality—and theological—around the categories of philosophy of religion, propositional Jewish theologies, and Jewish theology—frameworks for it. Ultimately, I attempt to highlight that religious practice is essential for a significant exercise of Jewish theology in a Jewish context and, simultaneously, that theological meditation is fundamental for a meaningful Jewish journey.
Religiosity and the Perception of Interreligious Threats: The Suppressing Effect of Negative Emotions towards God
Authors: Lam Dorcas Yarn Pooi , Koh Kai Seng , Gan Siew Wei , Sow Jacob Tian You
Published: March 2023

Religiosity has been studied for its impact on other sociological and psychological aspects of society, particularly personal wellbeing and interpersonal relationships. However, it has yet to be studied for its impact on interreligious prejudice as measured by perceptions of interreligious threats. The present study investigates how religiosity (both positive and negative measures) affects perception of threats from other religious groups within the Malaysian context by using the Centrality of Religiosity Scale and the Inventory of Emotions towards God as measures of religiosity. Data collected through questionnaires administered to university students and recent graduates (N = 260) in Malaysia were subjected to bivariate correlation analysis, multiple regression analysis and mediation analysis. Our findings show that the positive and negative measures yielded different effects on the perception of interreligious threats. While the centrality of religiosity and positive emotions towards God have statistically significant negative correlation with perception of interreligious threats, we show that negative emotions towards God suppresses the effect of the positive measures of religion on the dependent variable. The paper discusses the implications of these results within the socio-political context of Malaysia, in which ethnic identity and religious affiliation are closely intertwined.
Encounter Risk Evaluation with a Forerunner UAV
Authors: Bauer Péter , Hiba Antal , Nagy Mihály , Simonyi Ernő , Kuna Gergely István , Kisari Ádám , Drotár István , Zarándy Ákos
Published: March 2023

Forerunner UAV refers to an unmanned aerial vehicle equipped with a downward-looking camera flying in front of the advancing emergency ground vehicles (EGV) to notify the driver about the hidden dangers (e.g., other vehicles). A feasibility demonstration in an urban environment having a multicopter as the forerunner UAV and two cars as the emergency and dangerous ground vehicles was done in ZalaZONE Proving Ground, Hungary. After the description of system hardware and software components, test scenarios, object detection and tracking, the main contribution of the paper is the development and evaluation of encounter risk decision methods. First, the basic collision risk evaluation applied in the demonstration is summarized, then the detailed development of an improved method is presented. It starts with the comparison of different velocity and acceleration estimation methods. Then, vehicle motion prediction is conducted, considering estimated data and its uncertainty. The prediction time horizon is determined based on actual EGV speed and so braking time. If the predicted trajectories intersect, then the EGV driver is notified about the danger. Some special relations between EGV and the other vehicle are also handled. Tuning and comparison of basic and improved methods is done based on real data from the demonstration. The improved method can notify the driver longer, identify special relations between the vehicles and it is adaptive considering actual EGV speed and EGV braking characteristics; therefore, it is selected for future application.
Digital Rock Mass Analysis for the Evaluation of Rockfall Magnitude at Poorly Accessible Cliffs
Authors: Caliò Davide , Mineo Simone , Pappalardo Giovanna
Published: March 2023

The analysis of a digital rock cliff model, built by airborne photogrammetric data and infrared thermal images, is herein presented as an alternative tool for rock mass study in restricted and poorly accessible areas. Photogrammetric and infrared thermography techniques were combined for the geostructural and morphological characterization of an unstable cliff located in a nature reserve, where the rock mass extension and the environmental preservation rules required the use of minimally invasive surveying solutions. This methodological approach provided quantitative and qualitative data on both the spatial orientation of discontinuities and the location of major structural features, jutting blocks and past rockfall source areas. The digitally derived spatial data were used to carry out a rock mass kinematic analysis, highlighting the most recurring unstable failure patterns. Thermal images were overlapped to the photogrammetric cliff model to exploit the data combination and to analyze the presence of protruding rock mass volumes to be referred to as potential unstable volumes. Based on this activity, rock volumes were quantified on the digital model and the results were used to provide a zonation map of the potential magnitude of future rockfalls threatening the reserve. Digital data were validated by a field surveying campaign, which returned a satisfactory match, proving the usefulness and suitability of the approach, as well as allowing the quick and reliable rock mass characterization in the frame of practical use and risk management purposes.
Evaluating the Sensitivity of Polarimetric Features Related to Rotation Domain and Mapping Chinese Fir AGB Using Quad-Polarimetric SAR Images
Authors: Zhang Tingchen , Lin Hui , Long Jiangping , Zheng Huanna , Ye Zilin , Liu Zhaohua
Published: March 2023

Unaffected by cloud cover and solar illumination, synthetic aperture radar (SAR) images coupled with quad-polarimetric techniques have significant potential for mapping forest aboveground biomass (AGB) in the mountains of southern China. To improve the accuracy of mapping forest AGB, it is necessary to accurately interpret and evaluate the sensitivity of polarimetric features related to polarimetric response in complex forests. In this study, several rotated polarimetric features were extracted from L-band quad-polarimetric ALOS PALSAR-2 images based on uniform polarimetric matrix rotation theory. In addition, the sensitivity of rotated polarimetric features with forest parameters was evaluated by the Pearson correlation coefficient, sensitivity index (SI), and saturation levels. Ultimately, the forest AGB was mapped with various combinatorial feature sets by a proposed feature selection method based on the sensitivity index. The results illustrated that rotated polarimetric features extracted from the rotational domain have higher sensitivity with various forest parameters and higher saturation levels for mapping forests than other traditional features. After using the proposed feature selection method and combinatorial feature sets, the rRMSE of mapped forest AGB ranged from 22.5% to 33.9% for two acquired images, and the best result was obtained from the combination of three types of polarimetric features (BC + C4 + Ro). It is also confirmed that different types of features extracted from quad-polarimetric SAR images have better compensation effects and the accuracy of mapped forest AGB is significantly improved.