bluuebunny/crossref_metadata_2025 huggingface dataset:
Histomorphological evaluation of the combined therapeutic potential of Carica papaya and Musa paradisiaca on indomethacin induced gastric injury
Authors: Sylvanus Beredugo  , Emmanuel U. Eric  , Yibala I. Oboma  , Onome C. Sadjere
Published: December 2022

Background: Medicinal plants are often used for the preparation of remedies for the treatment of several ailments especially in rural areas. Objective: The study investigated the combined effect of Carica papaya (pawpaw) and Musa paradisiaca (plantain) leaves extract on the stomach walls of albino rats against indomethacin induced gastric ulceration. Materials and Methods: Twenty-five (n-25) albino rats were weighed and divided randomly into five groups. Each group consisted of five (n-5) rats. Group A served as negative control and received rat feeds and water ad libitum. Group B received feeds and a single dose of indomethacin (25 mg/kg body weight) via orogastric administration and organs were harvested 4 hours after administration. Group C rats were administered with Carica papaya leaf extract (250 mg/kg body weight) daily for 14 days. Group D was administered with Musa paradisiaca leaf extract (250 mg/kg body weight) for 14 days. Group E received combined extract of Carica papaya (250 mg/kg body weight) and Musa paradisiaca (250 mg/kg body weight) daily for 14 days. All the animals were allowed access to feed and water. The animals in groups C-E fasted for 24 hours and were administered with a single dose of indomethacin (25 mg/kg body weight). Four hours later, the animals were sacrificed under chloroform inhalation, organs harvested, processed and stained with haematoxylin and eosin for histomorphological evaluation. Result: The result of the study shows that the single dose of indomethacin caused gastric ulceration within 4 hours. Musa paradisiaca leaf extract ameliorated the effect of indomethacin on the stomach. Combination of Carica papaya and Musa paradisiaca leaves extract exacerbated the effect of indomethacin on gastrointestinal tract ulcers. Conclusion: The practice of using combined extract of Carica papaya and Musa paradisiaca should be avoided in ulcer patients or individuals on indomethacin therapy
Retardation of leaf senescence of aquatic plants using ascorbic acid
Authors: Chandan Kumar Pati  , Supravat Mahata
Published: December 2022

Potentiality of ascorbic acid on retardation of senescence was analysed using leaves of aquatic plant species namely Eichhornia crassipes and Jussiaea repens. Changes of some biochemical parameters like chlorophyll, protein as well as activity of catalase enzyme were analysed as reliable senescence indices during leaf senescence of the species under ambient ageing condition. With the progress of ageing duration from zero (0) to 96 hours the levels of chlorophyll and proteins in leaf discs gradually declined in both control and ascorbic acid treated samples. However, in the ascorbic acid treated samples the rate of decline was found to be much slower. The activity of the enzyme catalase was found to decrease progressively during the observation periods (0, 24, 48 and 96 hours) regardless of the treatment. Ascorbic acid partially alleviated the rapid fall of the enzyme activity during the ageing periods. Thus, ascorbic acid seems to be a potent senescence deferral agent for the experimental aquatic plant species
Next-generation sequencing proves clonal relationship between two distinguished lung and liver carcinomas by standard histopathology approach
Authors: Li Tian , Diks John , Trinh Nguyen Snow , Zeng Jianying , Chen Neil , Vignesh Shivakumar
Published: December 2022

Introduction: Two tumors having different histopathologies at anatomically distinct sites giving the picture of dual primary malignancies. Here we presented a case of two possible primary tumors and one secondary mass.

Case Report: A 74-year-old female, active smoker, without personal or family cancer history presented with early satiety and weakness for two months. Systems review was positive for a “raw” feeling in stomach, alleviated with antacids. Vital signs were stable with a negative abdominal exam. Lab showed leukocytosis 24.8 K/uL (3.5–10.8 K/uL) with left shift, microcytic anemia with hemoglobin 6.1 g/dL (12.0–16.0 g/dL), and reactive thrombocytosis 477 K/uL (130–400 K/uL). Contrast-enhanced computed tomography (CT) showed right upper lobe necrotizing cavitating lesion with reactive mediastinal and right hilar lymphadenopathy, two irregular hypodense lesions in pancreatic head and tail without ductal dilation with two irregular hypodense liver lesions. Immunohistochemistry of lung and pancreatic lesions were biopsied through endoscopic ultrasound (EUS), consistent with poorly differentiated squamous cell carcinoma (SCC) with extensive necrosis, which indicates pancreatic masses are likely metastases from the lung. Liver lesion biopsy exhibited high-grade neuroendocrine tumor (NET) with focal necrosis. Next gene sequencing was pursued. Given poor functional status, palliative immunotherapy was offered; however, the patient succumbed to respiratory failure.

Conclusion: Given the morphology and immunoprofile, differential diagnosis includes dual primary cancers with one metastasis, or primary SCC with metastasis with neuroendocrine differentiation. Despite having different histopathology and immunophenotype, both lung and liver tumors harbor the same molecular profile even at the variants of unknown significance that show identical mutations. As a result, they are directly related. TP53, RB1, MYCL1, and MEK1 mutations are more prevalent in SCC than NET. Tumor mutation burden values may vary as the tumor clonal structure varies between primary and metastatic sites, with higher rates of monoclonal structure recorded in metastases due to clonal selection, leading to a reduction in overall genetic diversity (“bottlenecking”). This raises the suspicion that the liver tumor is a SCC with neuroendocrine differentiation. The paucity of the specimen and rapid clinical course limited further investigation. Germline testing would have been useful to determine whether these findings are somatic or germline.
Keluarga Sakinah dalam Pandangan K.H. Hasyim Asy'ari (1871-1947 M) dan Relevansinya dengan Hukum Keluarga Islam di Indonesia
Authors: Aziz Muhammad , Harahap Abdul Aziz
Published: December 2022

This study aims to describe indicators of the formation of a sakinah family according to K.H. Hasyim Asy'ari and its relevance to the Compilation of Islamic Law (KHI). This qualitative research in the form of literature study uses philosophical normative. The main data source, namely the book Dhau' al-Mishbah fi Bayani Ahkam an-Nikah by K.H. Hasyim Asy'ari. Several articles in the KHI as the theory of analysis of this research. The results of the study show that there is a relevance between indicators for the formation of a sakinah family according to K.H. Hasyim Asy'ari with the construction of legal provisions in the Kompilasi Huukum Islam (KHI). First, the indicators of complying with the legal principles, requirements, and pillars of marriage that are relevant to KHI articles 4, 16, 20, and 27. It's just that the view of K.H. Hasyim in this first indicator tends to be textual. In contrast to KHI which is more contextual. Second, the recommendation indicator in choosing a life partner that is relevant to KHI Articles Articles 15, 16, 17, and 61. In this case, the criteria for the recommendation to choose a partner by K.H. Hasyim is more detailed covering various aspects, including religion, physical, lineage, economy, psychological and social status. Third, the indicator understands the principles of the purpose and benefits of marriage that are relevant to Articles 2 and 3. Third, the indicator is to build a good partnership in carrying out the rights and obligations of husband and wife that are relevant to the KHI Article 80. However, regarding the duties or obligations of the wife, K.H. Hasyim is more detailed than KHI. The theoretical implications of this research show indicators of the formation of a sakinah family in the view of K.H. Hasyim Asy'ari has relevance as well as can be the basis for formulas in the development and renewal of Islamic marriage law in Indonesia. The limitation of this research is that it has not studied in depth the heurmenetic aspects of the construction of the views of K.H. Hasyim is related to four indicators of the formation of a sakinah family.
KAJIAN YURIDIS KEJAHATAN PENCERNARAN NAMA BAIK MENURUT HUKUM POSITIF DAN HUKUM ISLAM
Authors: Rinda Rinda , Angga Krisna
Published: December 2022

The rapid development of science and technology also has an impact on the development of crime, one of which is the crime of defamation. Defamation is a crime that has its own characteristics that cannot be equated with crimes in general, because it is a special crime that needs to be regulated in a legal system. In positive law this act is regulated in Artides 310-321 of the Criminal Code and also Artide 27 paragraph (3) in conjunction with Artide 45 of the ITE Law. Then in Islamic law this act is induded in jarimah hudud. Normative legal research is legal research used in this research, which is prescriptive in nature by using sources of legal materials, booh primary legal materials and secondary legal materials. The approach used is comparative. The results of the study are that both Positive Law and Islamic Law explicitly regulate acts of defamation, these two legal systems have the same characteristics in determining the qualifications of defamation offenses and criminal liability, the only difference relates to the type of punishment given to the two perpetrators of defamation.
Intencionalidad en el Teatro Aplicado
Authors: Moreno-Serena Ulises
Published: December 2022

En el presente artículo, se reflexiona en torno a la intencionalidad como concepto diferenciador entre el teatro aplicado y el arte escénico. El teatro, como manifestación artística, ha propiciado la participación activa del público en sus últimos periodos de desarrollo, lo que se puede ver en los diferentes procesos de exploración, autoafirmación y propuestas de ruptura. De esta forma, en este escrito se explora cómo la intencionalidad puede ser comprendida como un mecanismo guía que articula al drama como un agente de transformación en diversos campos que se abarcan en el teatro aplicado y que lo diferencia del teatro como hecho artístico. Para lograr esta reflexión, se enfatiza en la presencia de la intencionalidad como un elemento fundamental del teatro aplicado, con lo que se centra la atención en el proceso y no sólo en el suceso, como pasa en el hecho artístico.
¿Es posible un teatro virtual?
Authors: García-Barrientos José Luis
Published: December 2022

Este ensayo propone un acercamiento reflexivo respecto de la oposición ‘presencial’ / ‘virtual’, y de paso discute las implicancias de

un estado de la cultura y sus efectos en el campo teatral. La pandemia por Covid-19 ha derivado en la definición de un nuevo orden,

condicionando las prácticas y por sobre todo las formas asociadas a la mediación perceptiva y comunicativa. De ahí la importancia de fijar posiciones y discutir aquello que define la especificidad del hecho teatral.
"Entre las dos orillas corre el río", de César Vallejo, y la poética del drama moderno
Authors: Dubatti Jorge
Published: December 2022

A partir de la teoría y la metodología de la Poética Comparada, este artículo analiza la contribución de César Vallejo (1892-1938) al drama moderno de visión marxista en Hispanoamérica. El análisis de "Entre las dos orillas corre el río", escrita en los años treinta y resultado de un complejo proceso de reescritura, se detiene en la relación del texto con la poética abstracta del drama moderno en versión ampliada, identifica los procedimientos canónicos y los de ampliación.
Hechos consumados, de Juan Radrigán: la dramaturgia como espacio de representación y reproducción de la memoria social
Authors: Johnson Tahina
Published: December 2022

El presente artículo, nacido a partir de la Tesis de Magíster con el mismo título, pretende referirse al rol de la dramaturgia chilena como espacio de representación de la memoria y el olvido de sujetos en contextos de abandono. A partir del análisis de la obra Hechos consumados, escrita por el dramaturgo Juan Radrigán, se busca entender cuáles son algunos de los elementos dramáticos de la obra que contribuyen a la producción y reproducción de la memoria social chilena. La investigación también pretende dilucidar de qué manera una obra teatral, a través de su puesta en escena, es capaz de evidenciar los diversos procesos y transformaciones políticas, culturales y sociales asociadas a su contexto de creación, convirtiéndose en un espacio de memoria específico. En el análisis son abordadas la puesta en escena original de Hechos Consumados, dirigida por Nelson Brodt el año 1981, y la puesta en escena realizada el año 2010 por Alfredo Castro.

Ambas se consideran casos en donde las memorias traumáticas de la dictadura son transmitidas y reproducidas por y para las generaciones venideras.
ANALYSE CRITIQUE DES MECANISMES PENAUX DE LUTTE CONTRE LE TRAFIC DES DROGUES ET DES PRODUITS STUPEFIANTS EN DROIT CONGOLAIS
Authors: ELEMBA Pascal MOTSHIKANA
Published: December 2022

Le droit international sur les stupéfiants est né d’un ensemble de traités internationaux et de conventions ratifiées par les pays signataires. Les conventions fournissent l’esprit des normes que les Etats retranscrivent à l’échelle nationale sous forme de lois ; elles lient les Etats signataires à certains principes qu’ils le voient contraints de respecter.

                  Le trafic de drogue étant un commerce international illicite comprenant la culture, la fabrication, la distribution et la vente de substances interdites par la loi, il convient de préciser que ce trafic de drogues appartient à un ensemble de pratiques illégales permettant de financer le crime organisé.

                  C’est pourquoi le trafic illicite de drogues génère des dommages non négligeables dans le monde. L’éventail des flux issus de cette activité donne lieu à l’apparition des organisations criminelles, des effets néfastes sur la santé publique et la question du blanchiment d’argent.

                  En effet, notre pays semble avoir une mauvaise application des lois, le trafic de drogues est considéré comme un crime en RDC, or les autorités n’imposent pas systématiquement la peine la plus sévère pour punir les trafiquants de drogues.

                  Or, Les lois actuelles dans notre pays datées depuis 1917 et n’ont jamais été modifiées, d’autant plus que la RDC joue un tout petit rôle actif dans les efforts visant à juguler le trafic de drogues et fait généralement preuve de peu de volonté s’agissant de combattre l’expansion intensive de cette activité à l’intérieur de ses propres frontières.
Female Athlete Triad Recognition and Knowledge of Collegiate Cross-country Coaches
Authors: Misra Madhu
Published: December 2022

The Female Athlete Triad (Triad) refers to the triad of low energy availability, impaired menstrual function and low bone density. However each component of the Triad is, in fact, a spectrum with energy availability ranging from normal to low, menstrual function ranging from normal to luteal phase defects and anovulatory cycles to frank functional hypothalamic amenorrhea (FHA, absence of menses) and bone density ranging from normal to low. There is obviously a need to engage coaches in education efforts so they know about the Triad and its components, can pass on this information to their teams, be comfortable discussing dietetic and menstrual issues with female athletes, and recognize Triad symptoms early and bring these to medical attention in a timely fashion. Coaches are in a unique position to educate athletes and prevent the Triad from developing or worsening over time, and to advocate for optimal resources including for the services of a sports dietician and psychologist.
Avaliação da presença de sintomas de ansiedade em acadêmicos de medicina de uma universidade do estado de Santa Catarina
Authors: Verbinnen Francielle Scheuer , Schiontek Letícia de Oliveira , Reis Maria Helena de Souza Cattete , Roveri Thaíssa Begnini , Pereira Eduardo Manoel , Martins Hugo de Oliveira
Published: December 2022

O curso de graduação em medicina é intrinsecamente extenuante, pois demanda alta carga horária de estudo, implicando em pouco tempo de sono e lazer, existência de autocobrança e familiar e de competitividade. Por isso, esta pesquisa avaliou o nível de intensidade de estudantes de medicina de uma universidade do Estado de Santa Catarina por meio da aplicação do questionário TAG-7. Dentre os 97 alunos que participaram, percebeu-se presença geral de ansiedade moderada. Entretanto, ansiedade severa esteve presente em prevalência de, respectivamente, 31,5% e 38,0% entre alunos dos ciclos básico e clínico. Ainda, estar no ciclo clínico assumiu correlação estatisticamente significativa com sentir-se nervoso, ansioso ou muito tenso, não ser capaz de impedir ou de controlar as preocupações, preocupar-se muito com diversas coisas e ficar tão agitado a ponto se tornar difícil permanecer sentado.
Fatores associados à resiliência em discentes do curso de medicina de uma universidade de Santa Catarina
Authors: Medeiros Annibal Nakamura de , Freire Karine de Mello , Rosa Luiza Cardoso Emerim da , Gonçalves Vinícius Gomes Noronha , Pereira Eduardo Manoel , Martins Hugo de Oliveira
Published: December 2022

O curso de graduação em medicina é intrinsecamente cansativo, exigindo muitas horas de estudo, aquisição de várias habilidades complexas. Essas características associadas com o isolamento social e a mudança do ensino presencial para o remoto agregaram fatores predisponentes a estresse significativo. Por isso, o presente estudo avaliou o nível de resignação dos estudantes de graduação em medicina de uma universidade do Estado de Santa Catarina por meio da Escala de Resignação de Wagnild. Foi encontrada alta resignação entre os 97 participantes, sendo a idade e o ciclo clínico significativamente associados de modo diretamente proporcional com encontrar formas de lidar com os problemas, sentir orgulho de si, autocrença para enfrentar as dificuldades, ter sentido de vida e ser alguém com quem contar em emergência. Apesar das características do ciclo clínico e da pandemia contribuírem para maior extenuação, os estudantes apresentaram resiliência suficiente para lidar com as dificuldades.
Um convite a uma sessão cinematográfica sobre as relações de poder na cozinha: o potencial da análise fílmica para o ensino da gastronomia
Authors: Braga Tereza Cristina Vieira , Café Anderson Luis da Paixão , Lima Gillian Leandro de Queiroga
Published: December 2022

O campo da gastronomia, de acordo com as agências de fomento à pesquisa no Brasil, está classificado na grande área das ciências da saúde. Entretanto, apesar dessa classificação oficial, pode-se dizer que a gastronomia é atravessada por uma série de questões teóricas e metodológicas, de natureza interdisciplinar, que a expande para além de suas fronteiras disciplinares. Nesse sentido, este artigo objetivou discutir a filosofia francesa de Michel Foucault, sobretudo a partir da fase genealógica do pensador, quando foram abordadas as principais características do poder disciplinar e do biopoder. Além dessa abordagem inicial, apresentou-se a análise fílmica da obra cinematográfica denominada “Gosto se discute” nos quais foram destacados trechos que evidenciaram a plena operacionalização das tecnologias de adestramento dos corpos no interior de uma cozinha de um tradicional restaurante paulista. Espera-se que o presente trabalho colabore para potencializar, cada vez mais, o uso de obras cinematográficas enquanto recurso didático e pedagogico no campo educacional.
As relações de trabalho no contexto da COVID-19 à luz da psicodinâmica do trabalho: revisão de escopo
Authors: Leal Cintra Rodrigues Thaísa Mara , De Marchi Barcellos Dalri Rita de Cássia , Bocalon Paulo Cesar , Scorsolini-Comin Fabio
Published: December 2022

Este estudo visa a sintetizar as contribuições da Psicodinâmica do Trabalho nas relações de trabalho inseridas no contexto da pandemia da COVID-19. Trata-se de uma scoping review que analisa estudos teóricos, empíricos e interventivos com abordagem teórica e metodológica atinentes à Psicodinâmica do Trabalho sobre o tema em debate especificamente no contexto brasileiro. A pergunta que orientou a revisão foi: quais as contribuições da Psicodinâmica do Trabalho na pandemia da COVID-19? As buscas ocorreram nas bases/bibliotecas CINAHL, Scopus, LILACS, PsycINFO, Academic Search Premier, EMBASE, Web of Science, PUBMED e Google Acadêmico. Foram recuperados 11 estudos que abordaram as contribuições da Psicodinâmica do Trabalho nas relações de trabalho no período pandêmico, publicados entre março de 2020 e janeiro de 2022. O adoecimento mental relacionado ao trabalho durante a COVID-19 foi intensificado, ao passo que reflexões profundas emergiram sobre a importância do trabalho. A clínica do trabalho pode ser uma medida efetiva para partilhar a dimensão subjetiva do trabalho, por meio da fala, da escuta e da expressão dos trabalhadores, o que foi evidenciado durante a pandemia da COVID-19.
Atributos da Atenção Primária à Saúde: elementos para o planejamento, monitoramento e avaliação em saúde
Authors: Marcelo Soder Rafael , Sarturi Fernanda , Fontana Darielli Gindri Resta , Kirsten Vanessa Ramos , Battisti Iara Denise Endruweit
Published: December 2022

Introdução: A Atenção Primária à Saúde tem como uma das principais porta de acesso as equipes de saúde da família, por meio de serviços organizados de maneira descentralizados e acolhendo as necessidades demandadas pelos usuários. Objetivo: Identificar os dez maiores escores gerais de municípios de uma região de saúde nos atributos da Atenção Primária, descrevendo os atributos de maior frequência. Método: Estudo transversal, envolvendo profissionais de saúde de 26 municípios da região noroeste do Rio Grande do Sul. Resultados: A média dos escores gerais dos atributos essenciais denotaram que o “acesso de primeiro contato-acessibilidade; coordenação do cuidado e; integralidade-serviços disponíveis” obtiveram avaliação mais elevada entre os profissionais dos serviços de saúde.  Conclusão: o estudo aponta a necessidade de reflexão sobre o planejmaneto, monitoramento e avaliação constante das políticas municipais, fluxos de serviços e educação permanente em relação aos profissionais.
Lagos e salares andinos: uma introdução sobre as suas características
Authors: Martinez Moreira Tatiana
Published: December 2022

Esse trabalho tem o objetivo de trazer algumas informações e características sobre uma área extremamente árida, com formações geológicas sedimentares, um ecossistema único e de grande interesse científico e econômico, trata-se dos Salares de regiões Andinas. Esses locais possuem lagos salinos; evaporitos formados pela cristalização e precipitação química dos sais dissolvidos, em um meio aquoso por evaporação; formação de dunas; vulcões ativos; além de um ecossistema complexo com microrganismos poliextremofílicos. As condições apresentadas podem ser utilizadas para estudos geológicos diversos; para pesquisas relacionadas com o início da vida na Terra, onde surgiram os primeiros microrganismos; além disso, como análogos terrestres para investigação sobre outros planetas, como Marte, utilizando a Astrobiologia como referência para busca de vida em outros planetas.
Antirracismo, pertinência étnico-racial e a reparação da escravidão
Authors: Costa Neto Antonio Gomes da
Published: December 2022

O artigo versa a respeito do Antirracismo como premissa da Pertinência Étnico-Racial, o qual faz surgir o dever da Reparação da Escravidão, a partir da observação da Constituinte de 1934, em especial, os aspectos relacionados à proposta eugênica da Política de Governo e do Estado. A Eugenia como discurso científico, transposto para a Política Pública, cujos propósitos estavam à exclusão da população negra da formação Brasileira, consequentemente, o apagamento do processo da diáspora forçada. Utiliza-se do pensamento Black Power como método que tem a capacidade de compreender, expor e comprovar sem recalcitrância ou temor de indicar o agente causador, em contraponto à prática da retórica discursiva do racismo sem autoria, dessa forma, discursos do passado que devem ser elementos para garantir o antirracismo. A reparação da escravidão, elemento chave da integração é o pertencimento pela identidade étnico-racial, o qual a causalidade, o nexo e a intencionalidade são demasiadamente conhecidos, não há como negar essa verdade, por essa razão o dever da reparação material e simbólica. Defendemos o pensamento Black Power como método e pensamento da filosofia de origem africana, de reconhecimento e pertencimento étnico-racial, instrumento científico que pode ser utilizado em diversos campos acadêmicos para garantir a Reparação da Escravidão.
Aprendizagem e competências de gerentes intermediários de uma Empresa Pública Tricentenária
Authors: Souza Valéria Xavier Bastos de , Villardi Beatriz Quiroz
Published: December 2022

Contexto: Considerando a Crise financeira enfrentada por uma Empresa Pública Tricentenária (EPT), com a perda de 70% de sua receita, repercutindo em balanço negativo nos exercícios subsequentes e inclusão no Programa de Parcerias de Investimentos da Presidência da República – PPI, em 2019, o que deflagrou clima organizacional negativo quanto a empregabilidade e futuro da EPT, em que grande pressão foi exercida sobre a liderança intermediária ou middle managers da EPT. Objetivo: propor capacitação gerencial específica, com base nos resultados obtidos com a pesquisa aplicada. Métodos: pesquisa qualitativa-interpretativista, 17 entrevistas semiestruturadas com oito duplas de líderes e liderados, de oito departamentos distintos, selecionados propositalmente. Os dados empíricos foram interpretados mediante análise qualitativa indutiva, da qual emergiram 12 categorias descritivas de 1ª ordem e 24 categorias de 2ª ordem. Resultados: A aprendizagem gerencial foi alcançada na prática laboral dos gerentes intermediários mediante a aprendizagem vivida no cotidiano, desenvolvendo competências técnicas e comportamentais e permitiram subsidiar a elaboração de um programa de capacitação gerencial específico ao contexto da EPT.
Os livros didáticos de história e suas abordagens no período da ditadura militar
Authors: Corrêa Cabral Rayanne , Bentes José Anchieta Oliveira
Published: December 2022

A presente pesquisa objetivou analisar os livros didáticos de história e suas abordagens no período da Ditadura Militar com a intenção de compreender como o ensino era repassado de acordo com os ideais militares exigidos da época. Nesse contexto o enfoque histórico deste trabalho foi ajustado, por meio de fundamentação teórica com autores que tecem considerações sobre como era ensinar história com atribuição do livro didático debaixo da cortina do regime militar. Como também frisar políticas de livro didático como a COLTED e FENAME criadas durante o regime. Vale ressaltar que o procedimento metodológico adotado na construção desta pesquisa, foi baseado em uma pesquisa qualitativa descritiva com a utilização de levantamentos bibliográficos onde foram atribuídos a contribuição e diálogo de autores sobre o ensino de história e o livro didático repassados em sala de aula durante o período militar.
Elaboração e análise físico químicas e sensorial de bolo utilizando corante natural a base de pitaya vermelha (Hylocereus polyrhizus)
Authors: De Oliveira dos Santos Gilvanda , De Souza Pahlevi Augusto , Souza Cruz Rafael , Batista Elisabeth Mariano , De Assis Regis Auriana , Silva Xavier Ruth Caroline
Published: December 2022

O objetivo do trabalho foi à elaboração e análise físico químicas e sensorial de um bolo utilizando suco de pitaya como corante natural. As pitayas (Hylocereus polyrhizus) foram adquiridas em Limoeiro do Norte - CE. Inicialmente foi feita a extração do suco concentrado. O bolo foi obtido a partir de uma receita básica aonde se utilizou além do suco da pitaya, ovos, açúcar, manteiga, leite, essência de baunilha, fermento em pó e farinha de trigo,.Foram homogeneizados e assados em forno a 220°C por, aproximadamente, 40 minutos.Na receita foram adicionadas duas quantidades de suco de pitaya (F1) 200 e (F2) 400 ml. Foram realizadas as análises de acidez titulável, pH e sólidos solúveis. Também foi realizada a análise sensorial utilizando escala hedônica de 9 pontos. As duas formulaçãoes de bolo utilizando diferentes concentrações de polpa de pitaya vermelha obtiveram resultados satisfatórios com relação aos aspectos sensoriais cor, aparência, aroma, sabor, textura e aceitação global. Conclui que a pitaya tem grande potencial para ser utilizada pelas indústrias alimenticias como corante natural por apresentar boa avaliação e coloração nas formulações.
The Effect Of Leadership And Compensation On Work Discipline At Napoly Jaya Building Store Company in Tasikmalaya City
Authors: Hidayat Mufti Kamil , Barlian Barin , Sutrisna Arga
Published: December 2022

This study aims to determine leadership and compensation for the work discipline of the Napoli Jaya building shop company. The method used is descriptive with a quantitative approach. pollution and a sample of 30 employees of the Napoli Jaya building shop based on the saturated sample technique. The analytical tool used is multiple linear regression. The results show that leadership and compensation simultaneously have a significant effect 12,944%. Partially, leadership has no effect 5,107% and compensation has a significant effect 46,922% on work discipline in the Napoli Jaya building shop.
The Effect of Sales Promotion (Through Facebook Media) on Interest in Buying Housing PT. Ascarya Builds Persada in Bengkulu City
Authors: Wahid Thariq Alhadi , Yunita Melda
Published: December 2022

This study aims to determine the effect of sales promotion (via Facebook media) on interest in buying housing at PT. Ascarya Bangun Persada Partially There is one independent variable (x) that will be discussed in this study, namely Sales Promotion which is the object of this research is the Consumer Housing PT. Ascarya Bangun Persada. In this study, there are several data analysis techniques used, including using instrument tests, analysis of respondents' responses, simple linear regression analysis, determinant coefficients, and also hypothesis testing. From the results of the simple linear regression test, the regression equation is obtained as follows: Y = 3.759 + 1.003 (X). Based on the simple linear regression equation above, it can be interpreted that: The constant value of 3.759 means that if the Sales Promotion variable (X) on Purchase Interest (Y) is equal to zero, then the Buying Interest variable remains 3.759. The coefficient of X (Sales Promotion) of 1.003 means that if the Sales Promotion increases by one unit, the purchase interest value will increase by 1.003. From the results of the tests that have been carried out, it can be concluded that the Sales Promotion variable (Through Facebook Media) has a positive and significant effect on Buying Interest in Housing PT. Ascarya Builds Persada of Bengkulu
The Influence of Motivation and Compensation on the Work Ethic of Employees of PT. Agrindo Seluma
Authors: Mardiyah Mardiyah , Saputra Juliyus
Published: December 2022

This study aims to determine the effect of motivation and work compensation on the work ethic of employees of PT. Agrindo Seluma either partially or simultaneously. There are several factors that will be discussed in this study, including motivation and compensation. The objects in this study are employees at PT. Agrindo Seluma, totaling 36 people. In this research, the writer uses data collection methods by means of observation, questionnaires or questionnaires and documentation. There are several data analysis techniques used in this study, including using multiple linear regression analysis, determinant coefficients and also hypothesis testing. The results of the study concluded that first, motivation has an effect on the work ethic of employees of PT. Agrido Seluma. The influence given by the motivation variable (X1) on the work ethic of employees (Y) is significant, it can be seen from the tcount value of 2.151 which is greater than ttable 2.005 and the sig value obtained is 0.018 which is smaller than 0.05. Second, compensation has an effect on the work ethic of employees of PT. Agrido Seluma. The effect given by the compensation variable (X2) on the work ethic of employees (Y) is significant, it can be seen from the tcount value of 2,695 which is greater than ttable of 2,005 and the sig value obtained is 0.001 less than 0.05. Third, motivation and compensation have a simultaneous effect on the work ethic of employees of PT. Agrido Seluma. The effect given by the employee benefits variable (X2) on the employee's work ethic (Y) is significant, it can be seen from the tcount 2,695 which is greater than ttable 2,005 and the sig value obtained is 0,001 which is smaller than 0,05.
Effect Of Leadership Style And Work Motivation On Employee Work Discipline PT. Nata Bersaudara Sejahtera
Authors: Ramdani Sahrul , Yusnita Rita Tri , Sutrisna Arga
Published: December 2022

This research was conducted with the aim of knowing the effect of Leadership Style and Work Motivation on Work Discipline of Employees of PT Nata Bersaudara Sejahtera. The method used in this research is a survey with a quantitative approach. Data collection techniques were obtained directly through questionnaires distributed to 89 respondents who were employees of PT Nata Bersaudara Sejahtera. The technique used in this research is path analysis. The results of the study indicate that: (1) Leadership style has a positive and significant effect on work motivation for employees of PT Nata Bersaudara Sejahtera; (2) Leadership style directly has a positive but not significant effect on the Work Discipline of PT Nata Bersaudara Sejahtera employees; (3) Work Motivation has a direct positive and significant effect on the Work Discipline of PT Nata Bersaudara Sejahtera employees; (4) Leadership style has a positive and significant effect on work discipline through the work motivation of employees of PT. Nata Bersaudara Sejahtera.
The Influence Of Work Discipline And Quality Of Worklife On The Performance Of Employees Of The Ministry Of Religious Affairs Office Of Tasikmalaya Regency
Authors: Aulia Renita Hera Nurul , Rahwana Kusuma Agdhi , Sutrisna Arga
Published: December 2022

This study aims to find out how much influence Work Discipline and Quality Of Work Life have on Employee Performance at the Tasikmalaya Regency Ministry of Religious Affairs Office. The method used in this study is quantitative with a survey approach. With a research sample of 41 people as respondents to the Tasikmalaya Regency Ministry of Religious Affairs Office based on 41 known population data. The data used is using primary data. The analysis tool used in this study is multiple linear regression using the SPSS support application version. Based on data that have met the validity test, reliability tests and classical assumption tests are processed so as to produce regression equations as follows: Y = 73,820 + 0.388 X_1 + 0.392 X_2.  The test results showed that partially showing the variables used in the study, namely work discipline and quality of work life, had a significant effect on the performance of employees at the Tasikmalaya Regency Ministry of Religious Affairs Office. Simultaneously there is a positive and significant influence of work discipline and quality of work life together on employee performance based on the testing of multiple linear regression analysis obtained fghitung of 73,820 signatures of 0.001. With the Determination Coefficient test, it gets an R Square value of 0.398 or 39.80%. It shows the influence of Work Discipline and Quality Of Work Life on Employee Performance and 60.20% is the influence of other variables beyond the variables used in this study.
The Effect Of Quality Of Service And Promotion On Purchase Decision (Consumer Survey at Sandy Make up Tasikmalaya)
Authors: Setianingsih Neti , Muhamad Pauzy Depy , Putri Lestari Suci
Published: December 2022

This study aims to determine the effect simultaneously and partially of Quality of service, Promotion, Purchase Decision in Sandy Make up Tasikmalaya City. The method used in this research is method a survey. The research data were obtained by distributing questionnaires to 100 respondents. Data analysis in this study used multiple regression analysis using SPSS software. The results of this study indicate that the Quality of service, Promotion simultaneously have a significant effect on Purchase Decision. Quality of service partially significant effect Purchase Decision. promotion has a significant effect on Purchase Decision.
The Effect Of Caf Menu Variations And Atmosphere On Competitive Advantage (Case Study on Volkswagen Café in Tasikmalaya)
Authors: Permana Andri Esa , Yusnita Rita Tri , Lestari Suci Putri
Published: December 2022

This study aims to determine the effect of menu variations and cafe atmosphere on competitive advantage (a case study on Volkswagen Café in Tasikmalaya). The method used in this study is causality through a survey approach. With a research sample of 100 consumers of Volkswagen Café in Tasikmalaya. The data used is primary data. The analytical tool used in this study is multiple regression using SPSS 26.0. The results showed that the menu variation has a very good rating classification, the cafe atmosphere has a  good rating classification, while the competitive advantage has a very good rating classification for Volkswagen Café Consumers in Tasikmalaya. Simultaneously, menu variations and cafe atmosphere have a significant influence on competitive advantage. Partially, menu variations have a significant effect on competitive advantage and cafe atmosphere has a significant influence on Volkswagen Café's competitive advantage in Tasikmalaya.
The Influence Quality Of Goods And Service Quality On Consumer Statisfaction Of Ano Abadi Meubel Cikatomas
Authors: Yoansyah Isep , Sutrisna Arga , Pauzy Depy Muhamad
Published: December 2022

The purpose of this study was to determine the effect of the quality of goods and service quality simultaneously or partially on consumer statisfaction of Ano Abadi Meubel Cikatomas. Survey of Ano Abadi Meubel consumers in Cikatomas. The research method used is descriptive and verification  method. The sample in this study amounted to 100 respondents. Data collection was carried out using a questionnaire. The data analysis used is multiple regression analysis. The results of this study indicate that quality of goods and service quality simultaneously have a significant effect on consumer statisfaction. Partially, quality of goods has no significant effect on consumer statisfaction. Partially, the service quality has a significant effect on consumer statisfaction.
BALKAN EDEBİYATLARINDAN SEÇME HİKÂYELER I ÇAĞDAŞ YUNAN EDEBİYATI
Authors: KIRLIDÖKME Utku
Published: December 2022

BALKAN EDEBİYATLARINDAN SEÇME HİKÂYELER I
ÇAĞDAŞ YUNAN EDEBİYATI isimli çalışmanın tanıtım yazısıdır.
Progressive muscle relaxation technique effectiveness on pain and fatigue among post-mastectomy women
Authors: Elsaba Howaida Amin Hassan Fahmy , Mohamed Safaa H , Sweelam Marwa Yehia Moustafa , Younes Mona Mohamed Abd El Hamid , Ahmed Safaa Ibrahim
Published: December 2022

Background: Post-Mastectomy Pain (PPMP) and fatigue are common conditions that can follow surgeries for breast cancer, the most common cancer in women. The progressive muscle relaxation technique appears to be effective, affordable, low-risk, adaptable, and simple to use. Because of the frequency of PPMP and its potential severity, it has received increasing research attention. Aim:  To evaluate the effectiveness of progressive muscle relaxation techniques on pain and fatigue among post-mastectomy women. Design: A quasi-experimental design was used to conduct this study. Setting: The study was conducted at the inpatient and outpatient clinic of Sohag Oncology institution. Subject: A purposive sampling technique was enrolled to select a sample of 50 post-mastectomy women who were randomly assigned into two equal groups, with 25 post-mastectomy women in each group (the experimental and control groups). Tools: Three tools were used (I) demographic data of Post mastectomy women sheet, (II) a Visual Analogue Scale, and (III) a fatigue assessment scale. Results: The current study revealed that the majority of post-mastectomy women in the intervention group experienced mild pain and fatigue reduction during the post-test compared to the control group.
Frontal sinus and its outflow tract
Authors: Acharya S , Dash A
Published: December 2022

Introduction: The frontal sinus and its outflow tract attracts special concern for the budding otorhinolaryngologists because of its complex location, variation in anatomy and disease processes altering its pathophysiology.The surgical management is  challenging and a surgeon must be well aware of its anatomical variation, radiological finding to anticipate the best surgical outcome. Objectives:-To review the frontal sinus and its drainage pathway with respect to anatomy radiology and  different surgical methods. Data Analysis:-The FS presents a variety of anatomical variation and multiple pathological situations can direct multiple surgical approaches to deal with them. FR is the area of  “surgical bottleneck” with maximum narrowing endoscopically and beginners must know the boundaries of safe work to have an optimal outcome. Chronic rhinosinusitis, frontoethmoidal mucocele and Osteomas are common disease process affecting frontal sinus and there are vast variant of malignant tumors that can affect the area posing special challenge to surgeon, Conclusion:- Different surgical pathologies affect frontal sinuses and its outflow tract which can be managed successfully if surgeon has good knowledge of its relevent anatomy and by use of appropriate surgical tools and individualized approach.
Septoplasty in peadiatric population
Authors: Acharya S , Dash A , Satpute S
Published: December 2022

Septoplasty in children is controversials due to concerns over an adverse effect on nasal and facial growth. Recent evidence has confirmed that septoplasty can be safely performed without affecting  nasofacial development in properly selected pediatric patient. The purpose of this article is to establish the impact of pediatric septoplasty on nasal and facial growth and review the clinical indications and evidence for timing of surgery according to the most recent literature. A structured review of the PubMed, Ovid Medline and Cochrane Collaboration databases (Cochrane Central Register of Controlled Trials, Cochrane Database of Systemic Reviews) was undertaken, using the terms: pediatric, childhood, septoplasty, nasal septum, indications, nasal growth and facial growth. A further similar study concluded that external septoplasty does not affect most aspects of nasal and facial growth, but may negatively influence growth of the nasal dorsum. Furthermore, one study demonstrated that a group of children with symptomatic uncorrected deviated nasal septum had a statistically significant increased occurrence of facial and dental anomalies compared with age and sex matched controls, therefore supporting a role for septoplasty. Conclusions: Evidence exists to support that pediatric septoplasty can be performed without affecting most aspects of nasal and facial growth.
ENSAIO CLÍNICO RANDOMIZADO CONTROLADO SOBRE O CORTE DO CATETER CENTRAL DE INSERÇÃO PERIFÉRICA EM NEONATOS
Authors: dos Reis Wosnes Thaline , Giacomozzi Clélia Mozara , Giacomozzi Letícia Morgana , Vieira Cavalcante Silva Regina Paula
Published: December 2022

Objetivo: Comparar as complicações entre o Cateter Central de Inserção Periférica com ajuste de comprimento com corte e sem corte.

Método: Ensaio clínico randomizado controlado. Compuseram a amostra 46 neonatos internados num serviço de Unidade de Terapia Intensiva Neonatal no Paraná, Brasil, entre abril e julho de 2021, com indicação do cateter. Os participantes foram randomizados eletronicamente e divididos em grupo controle, cujo comprimento do cateter foi ajustado com o corte do mesmo, e grupo experimental, cujo cateter foi mantido sem corte. Os dados foram analisados por teste de Mann-Whitney e Teste de Fisher.

Resultados: A média do tempo de permanência dos cateteres foi de dez dias em ambos os grupos (p=0,79). Não foi identificada diferença relevante quanto às complicações, como infiltração, obstrução e infecção.

Conclusão: O corte do cateter para ajuste do comprimento não interfere nas complicações apresentadas. Registro no REBEC: RBR-2w4dpg5.
TIME TREND AND SPATIAL DISTRIBUTION OF DENGUE IN BRAZIL
Authors: Rodrigues da Silva Thiago , Araújo Nascimento Costa Ana Karla , Araújo Nascimento Alves Kelle , Neves Santos Alisson , de França Cota Matheus
Published: December 2022

Objective: to determine the time trend and spatial distribution of the confirmed dengue cases in Brazil between 2009 and 2019.

Method: this is an ecological and longitudinal study of a historical series of the dengue cases available in the Information System of Notifiable Health Problems. The data were analyzed by means of time trend and spatial distributions.

Results: the study denoted a stationary trend of the incidence coefficient (R=0.091; p>0.05). The Midwest region stood out among the Brazilian regions, with 42.04% incidence. In relation to the Brazilian states, Acre was the one with the highest incidence: 45.06%. Finally, regarding the severe form of dengue, the Southeast region stood out with 38.35% of the cases.

Conclusion: based on the epidemiological analyses, it was concluded that, in Brazil, dengue is still a relevant public health problem, given the high number of cases.
TENDENCIA TEMPORAL Y DISTRIBUCIÓN ESPACIAL DEL DENGUE EN BRASIL
Authors: Rodrigues da Silva Thiago , Araújo Nascimento Costa Ana Karla , Araújo Nascimento Alves Kelle , Neves Santos Alisson , de França Cota Matheus
Published: December 2022

Objetivo: determinar la tendencia temporal y la distribución espacial de los casos confirmados de dengue en Brasil entre 2009 y 2019.

Método: estudio ecológico y longitudinal de serie histórica de los casos de dengue disponibles en el Sistema Información de Enfermedades Notificables. Los datos se analizaron por medio de tendencia temporal y distribución espacial.

Resultados: el estudio denotó una tendencia estacionaria del coeficiente de incidencia (R=0,091; p>0,05). La región Centro-Oeste de Brasil se destacó con el 42,04% de incidencia de casos. En relación con los estados del país, Acre fue el que obtuvo mayor incidencia: 45,06%. Finalmente, en cuanto a la forma grave de dengue, la región Sudeste se destacó con el 38,35% de los casos.

Conclusión: a partir de los análisis epidemiológicos se concluyó que, en Brasil, el dengue sigue siendo un problema de salud pública relevante, considerando la elevada cantidad de casos.
EFFECTIVENESS OF ASCORBIC ACID AND SALINE SOLUTION IN PEDIATRIC CENTRAL VENOUS ACCESS: RANDOMIZED CLINICAL TRIAL
Authors: Giacomozzi Letícia Morgana , Vieira Cavalcante Silva Regina Paula , Reichembach Danski Mitzy Tannia , Eduardo Carreiro José , Figueira da Silva Rodrigo , Mozara Giacomozzi Clélia , dos Reis Wosnes Thaline
Published: December 2022

Objective: to compare the effectiveness between the use of ascorbic acid and 0.9% saline solution in the prevention of pediatric central venous catheter obstruction.

Method: randomized clinical trial conducted in a public hospital in Paraná, between the months of June 2018 to October 2019 with 152 participants, of which, 73 in the experimental group and 79, control group) who underwent central venous catheter insertion and randomized to receive the flush intervention with ascorbic acid or 0.9% saline solution.

Results: Catheter obstruction occurred in 17 cases (11.2%), nine (11.4%) in the control group and eight (10.9%) in the experimental group. Thrombotic obstruction occurred in 15 cases, in a similar way, in both groups (p=0.88). Catheter removal occurred in 82 cases for elective reasons and in 63 cases for complications.

Conclusion: the use of ascorbic acid is as efficient as 0.9% saline solution in preventing central venous catheter obstruction. The study expands the possibilities of interventions within the theme.