bluuebunny/crossref_metadata_2025 huggingface dataset:
Platfrom Video Game sebagai Media Terapeutik
Authors: Yunike Yunike , Kusumawaty Ira
Published: August 2023

This study attempts to use video games therapeutically, which can be used as a rationale for developing and utilizing video games as a therapeutic medium. This research method uses the PRISMA approach using the keywords "video game" and "teenagers," "mental health," and "intervention" in the Scopus electronic database, google scholar, Science Direct and Pubmed with a range of years 2018 to 2022. Based on the research results, they have identified the definition of video games along with their platforms and the use of video games to improve mental health for humans of all ages, especially adolescents. It is proven that improving the physical condition of older adults can involve the role of video games as a medium in them. In conclusion, thus, the study of the development and use of video games is urgent to help improve human health status.

Keywords: Adolescent Mental Health, Therapeutic Media, Video Games
Intervensi yang Mendukung Kualitas Hidup Penyintas Tumor Otak
Authors: Kumalasari Renie , Gayatri Dewi , Afiyanti Yati
Published: August 2023

This study aims to examine interventions that have an impact on the quality of life of brain tumor survivors based on the results of previous studies. Methods: This study is a literature review. Article search through Science Direct and Pubmed and Google Scholar databases. The search keywords are: brain tumor, QOL, RCT, Intervention. The Boolean logic used is "AND" and "OR". The search also activates special filters such as: article type: research article, access type: open access & open archive, and text availability: free full text. Results: 5 articles that passed the selection were reviewed. Based on the articles reviewed, this study found that various interventions had a positive impact on the quality of life of brain tumor survivors. The interventions are in the form of yoga, health promotion based on traditional Chinese medicine (TCM) and peer support (The Ohana Project), high-quality nursing, pilates-based group therapy, and ski training. Conclusion: based on the findings of this study, interventions that have a positive impact on the quality of life of brain tumor survivors need to be improved. Future studies may use a larger sample to corroborate the findings.

Keywords: intervention; quality of life; brain tumor.
Perawatan Metode Kanguru terhadap Kenaikan Berat Badan Bayi
Authors: Emiria Windi Nur , Rustina Yeni , Rachmawati Imami Nur
Published: August 2023

This study aims to provide an overview and ideas from the results of research that has been published regarding the effectiveness of the kangaroo method of treatment for weight gain in LBW. The method used is a systematic review through search strategies in 8 electronic databases (Taylor & Francis Online, ProQuest, Semantic Scholar, Scopus, Science Direct, PubMed, Ebscohost, & Google Scholar). The keywords used in the search were (premature OR "low birth weight infant") AND ("kangaroo mother care" OR " kangaroo care") AND ("weight gain" OR growth OR "infant weight gain"). The results showed that most kangaroo method care is intermittent PMK. PMK is given at any time, usually when parents visit their babies. The duration of PMK implementation varies from 30 minutes in one day to 20 hours in one day. In conclusion, the kangaroo method treatment is proven to be effective in increasing the baby's weight compared to conventional treatments that are usually done.

Keywords: LBW, Infant Weight Gain, Kangaroo Method Care
Penggunaan Telehealth atau Telenursing di Indonesia selama Pandemi COVID-19
Authors: Putri Shafira  Amalia , Sudaryanto Agus
Published: August 2023

This study aims to find the literature that discusses telehealth or telenursing in Indonesia during the COVID-19 pandemic. The method used in writing is a literature review. The study results in show that telehealth benefits patients and health service providers by increasing the knowledge of medical staff and updating knowledge to improve the health services provided. The health promotion offered can be carried out more optimally, and with this telehealth, nurses can monitor the patient's condition to determine whether the behavior is under the health promotion offered. In conclusion, telehealth can be used as a solution in remote care to limit direct contact. The use of telehealth or telenursing has a very positive impact. Patients can only complete treatment by telephone, computer, internet, video, and audio conferencing. The time spent in remote care is also quite effective.

 

Keywords: COVID-19 pandemic, Telehealth, Telenursing
Perilaku Kesehatan Penderita Hipertensi
Authors: Salsabila Firyal Tsamarah , Kristinawati Beti
Published: August 2023

This study aimed to explore the description of the health behavior of hypertension sufferers in coastal areas, especially in Ketapang District, South Lampung Regency, Lampung Province. This study uses a qualitative method with a narrative approach with unstructured interviews. The study's results identified seven main themes: food and drink consumption patterns at risk of hypertension, smoking habits, lack of physical activity, poor stress management, use of hormonal contraception, non-compliance with antihypertensive drug therapy, and routine blood pressure checks. The conclusions from the statements of twenty-seven informants who experienced hypertension had health behaviors that were at risk of hypertension in the form of eating and drinking patterns that were at risk of hypertension, active and passive smoking habits, lack of physical activity, poor stress management, disobedience with drug therapy antihypertensives, and some check their blood pressure regularly and also those who do not have their blood pressure checked periodically.

 

Keywords: Hypertension, Health Behavior, Coastal, Qualitative Study
Terapi Komplementer dalam Mengatasi Gangguan Tidur Pasien yang Menjalani Hemodialisis
Authors: Rasmiati Rasmiati , Herawati Tuti , Sukmarini Lestari
Published: August 2023

This study aims to collect relevant information on the effectiveness of complementary therapies in treating sleep disturbances in patients undergoing routine hemodialysis. The method used in this study is a literature study by collecting and reviewing several published articles regarding the role, use, and effect of complementary therapy in patients on routine hemodialysis with sleep disturbance problems. The results showed the effectiveness of complementary therapies such as music therapy, acupressure, and Benson's relaxation in overcoming sleep disturbances and improving patients' sleep quality. In conclusion, the three complementary therapies can overcome sleep disturbances and improve hemodialysis patients' sleep quality. However, of the three therapies, the authors concluded that Benson's relaxation intervention was an intervention that had better effectiveness than other complementary therapies.

Keywords: Complementary Therapy, Sleep Disorders, Hemodialysis
Redes de integração ensino-saúde bucal: análises sobre cuidado, gestão e processo de trabalho
Authors: Warmling Cristine Maria
Published: August 2023

O livro apresenta pesquisas sobre a temática da Saúde Bucal Coletiva conduzidas, entre os anos de 2016 e 2019, por estudantes da Pós-graduação e da Graduação. Sistematiza um conjunto de novos conhecimentos e práticas a respeito das Redes de Atenção e de Ensino na Saúde Bucal em suas interfaces com as estratégias de Integração Ensino-Serviço.
Perencanaan Produksi Makanan Laut dengan Pertimbangan Permintaan dan Kapasitas
Authors: Rachman Hirman , Mawengkang Herman
Published: August 2023

The sea holds many resources that are very important for life, and one of them is the potential of fisheries, which is a basic human need. Indonesia, as a maritime country whose waters cover 2/3 of its territory, most of its people who live in coastal areas have utilized this condition by conducting fisheries management activities. However, the process still needs technical support to optimize the results. This research will review the production planning process of processed marine products under demand uncertainty. This research will construct a model to minimize production costs by considering demand uncertainty. The model will be computed using Mixed Integer Linear Program (MILP) method to provide the decision of processed products produced and the amount of production.
Introduction
Authors: Al-Khalili Charlotte , Holst Birgitte Stampe
Published: August 2023

How is conflict reshaped by and through the displacement of millions of people into neighboring countries? Does conflict follow displaced people and how does this spatial rupture reconfigure conflict itself? Based on ethnographies of Syrians in Lebanon, Turkey, Iraq and Syria, this introduction to a special section on displaced conflict argues that displacement, generating a spatial rupture between people and the state, layers conflict by embedding state level competitions over power in intimate relationships. Moreover, displacement inscribes the altered stakes of everyday social life into state level politics. In displacement, the Syrian conflict re-emerges as a layer of decision about, for instance, where and how to bury the deceased, just as shifting forms of solidarity between Syrians and Lebanese becomes one layer of what the conflict is all about. As such, comprehending the conflict and the transformations it instigates in people's lifeworlds requires attention to the layering induced by spatial rupture.
Pre-Service Teachers’ Voices: The Challenges in Dealing Classroom Management Problems During Teaching Practice
Authors: Maulidina Ninda , Maisa Maisa , Rozak Diana Rahmawati
Published: August 2023

This study focuses on the classroom management problems of pre-service teachers during teaching practice and how they apply teaching strategies to overcome those problems. The method used is a qualitative narrative inquiry with data sources that have been collected through a questionnaire, documents evidence and interviews. Data analysis for this study used thematic analysis. The results of the analysis found that classroom management problems are one of the difficulties and challenges for pre-service teachers. The setting of strategies in lesson planning and managing in the classroom is really needs to be considered by pre-service teachers to achieve the learning goals. Efforts that can be made with the help of using pre-service teachers when facing classroom management problems are designing the teaching strategies and pre-service teachers need to provide motivation, instruction and pay attention to student behavior.
Project Based Learning (PBL) in English Drama Course: The Process and Its Impact on Students’ Speaking Skill
Authors: Kusmaryani Woro
Published: August 2023

Project Based Learning (PBL) is a type of instruction whereby students spend a significant amount of time investigating and responding to a complex issue, problem, or challenge in order to learn knowledge and skills in the form of project. The objectives of this research were revealed the running process of PBL in English Drama course and investigated its impact on students’ speaking skill. This research was mixed-methods research, a case study at English Education Department of Universitas Borneo Tarakan. One lecturer and one class of students who attended the English Drama course served as the research subjects. This research collected quantitative and qualitative data such as documents, observation, and test. This data was analyzed quantitatively and qualitatively through coding and statistical analysis paired t-test. The results showed that the running process including Investigation, Planning, Implementation, and Reflection. The paired t-test result showed that Sig. 0.000 < 0.05, PBL implementation significantly enhances students' speaking abilities in English drama performance.
Composing Digital Multimodal Notices Using the InShot Application as Learning Media
Authors: Nurviyani Vina , Dewia Luthfita Aulia
Published: August 2023

Digital technology has become very influential globally, particularly in developing learners' writing skills. This study investigated the implementation of the InShot application in creating digital multimodal notices. Moreover, it explored the strengths and weaknesses of the InShot app applied as the learning media in composing digital multimodal notices. The study used qualitative design (a case study) involving 27 students studying at a junior high school in West Java. Observations, open-ended questionnaires, and documents were applied to the data collection. The result shows that implementing the InShot app gives EFL learners optimal stimulus in composing digital multimodal notices and developing their writing skills. It is manifested in their composition of digital multimodal notices reflecting complete generic structure, correct linguistic features, and matching images expressing the full meanings of the notices. Besides, they show positive responses. In this case, they are excited and interested in composing digital multimodal notices using the Inshot app. They combined appropriate colours, fonts, and backgrounds to create the meanings of the notices. The Inshot app facilitates learners to integrate the meanings presented in verbal, visual, and audio modes harmoniously, so the purpose of the notices is complete. However, learners with less digital literacy need help integrating the appropriate modes in composing digital multimodal notices.
A Comparative Study Between Javanese and Madurese Reduplication
Authors: Maryani Maryani
Published: August 2023

The purpose of this study is to find out the similarities and differences both in the form and the function of the reduplication between Javanese and Madurese. This research used descriptive qualitative method. The data were taken from Javanese and Madurese words. Madurese words will be collected randomly from some respondents who came from Madura, especially taken from daily conversation in the domain of the family.  And discourse in Madurese folktale. Whereas, Javanese words will be taken randomly from Djaka Lodang magazine edition of Desember 2020, November 2021, Januari 2022 and some informants who come from Java especially in Bantul-Yogyakarta. The result showed that there were some similarities between Javanese and Madurese reduplication in the forms, such as: full reduplication, partial reduplication, reduplication combined with affixation, reduplication with sound modification and the word resembles of reduplication. While in the function have two types, i.e. inflective reduplication and derivative reduplication. Meanwhile, for the differences of reduplication, Javanese does not have the forms of final syllable reduplication, whereas Madurese does have and it is very dominant in daily conversation both in the formal or informal situation. The functions of reduplication, Javenese has class word Noun to be Adjective, whereas Madurese does not have.
SISTEM PAKAR DIAGNOSIS PENYAKIT BERDASARKAN KELUHAN SAAT KEHAMILAN MENGGUNAKAN METODE FORWARD CHAINING DAN CERTAINTY FACTOR (STUDI KASUS : KLINIK ALQILA)
Authors: Ramadhan Ryan , Jamaludin Asep , Solehudin Arip
Published: August 2023

Penyakit saat kehamilan banyak dialami di Indonesia, berdasarkan Riset Kesehatan Dasar (RISKESDAS) tahun 2018 terdapat 48.9% ibu hamil mengalami penyakit anemia, 5,6% mengalami ketuban pecah dini, 3,6% mengalami plasenta previa, 48,9% mengalami hiperemesis gravidarum, preeklampsia dan aborsi. Oleh karena itu, dibutuhkan sistem pakar yang dapat mendiagnosis penyakit saat kehamilan. Sistem pakar ini menggunakan metode forward chaining dan certainty factor serta menggunakan metode pengembangan Expert System Development Life Cycle (ESDLC) dengan tahapan dimulai dari tahap penilaian keadaan, akuisisi pengetahuan, perancangan dan design, pengujian, dokumentasi, dan pemeliharaan. Hasil pengujian black box testing dan hasil white box testing yaitu sistem sudah berjalan dengan baik dinyatakan berhasil, lalu hasil uji pakar yaitu sistem sudah sesuai pengetahuan dan penalaran pakar, hasil kuesioner yang di bagikan kepada 30 pengguna diperoleh penilaian dari sisi tampilan 87,67% dan dari sisi manfaat 87,5%.
LITERATURE REVIEW: TERAPI KOMPLEMENTER UNTUK MENINGKATKAN KUALITAS HIDUP WANITA PREMENOPAUSE
Authors: Alifah Umi Nur
Published: August 2023

Premenopause is a transitional period experienced by women when they are about to enter menopause. At this stage, a woman will experience a decrease in the hormone estrogen, giving rise to premenopausal syndrome. Common symptoms of premenopausal women due to changes in body systems manifest in complaints in the form of hair loss easily, irritability or sensitivity, insomnia, frequent sweating, and decreased sex drive. These changes and symptoms occur around 2-3 years before menopause. The prevalence of depression and anxiety in women will increase when entering the premenopausal and postmenopausal phases. A study in China described depressive symptoms experienced by women increasing from 14.5% (premenopausal) to 19.6% in the postmenopausal period. The prevalence of anxiety symptoms increases from 3.1% (premenopausal) to 7.4% in the postmenopausal period. This type of research is a literature review. Data is accessed from various existing database sources such as; Google Scholar, PubMed, Science Direct, Sage Pud, ProQuest. Literature reviewed in the range of 2013 to 2023. The main topic search keywords are; complementary, premenopausal, anxiety, quality of life, woman, psychoeducation. The results of this study concluded that providing complementary therapy for premenopausal women has an effective effect on improving quality of life and reducing anxiety in premenopausal women. According to the researchers' analysis, complementary therapy can reduce vasomotor symptoms, reduce stress and depression in women.
О Программе Организации Объединенных Наций «Атмосферные выпадения тяжелых металлов в Европе – оценки на основе анализа мхов-биомониторов»
Authors: Фронтасьева М.
Published: August 2023

Одним из важнейших аспектов в решении задач охраны окружающей среды и здоровья человека является контроль качества атмосферного воздуха. К наиболее опасным загрязнителям окружающей среды относятся тяжелые металлы (ТМ). В большинстве европейских стран потребность в изучении последствий их воздействия на окружающую среду и здоровье человека привела к созданию национальных и международных программ по биомониторингу атмосферных выпадений тяжелых металлов. Данные об атмосферных выпадениях ТМ и других токсичных элементов собираются на основе анализа мхов-биомониторов, служащих аналогом аэрозольных фильтров. Под эгидой Комиссии ООН по трансграничному переносу атмосферных выпадений в Европе (UNECE ICP Vegetation) каждые 5 лет издается Атлас атмосферных выпадений тяжелых металлов. В статье сообщается об вкладе интернационального коллектива сектора нейтронного активационного анализа и прикладных исследований ЛНФ ОИЯИ в эти Атласы, начиная с 1995 года. Изучение атмосферных выпадений тяжелых металлов и других токсичных элементов в ряде стран-участниц и неучастниц ОИЯИ (Азербайджан, Албания, Армения, Беларусь, Болгария, Греция, Грузия, Казахстан, Молдова, Польша, Румыния, Словакия, Западная Украина, Северная Македония, Сербия и Хорватия), включая некоторые территории Центральной России (Московская, Тульская, Тверская, Ивановская, Ярославская, Владимирская, Самарская, Рязанская области), а также Южный Урал и Северный Кавказ (Республика Ичкерия, Северная Осетия) позволило выявить и оценить ареалы этих загрязнений на исследованных территориях и провести сравнение с уровнями аналогичных загрязнений в странах Западной Европы. В настоящее время обсуждается возможность расширения этой программы на страны Азии и Тихоокеанского побережья.
Reflection of the names of artificial and natural water sources in the study of microhydronyms of Zhambyl region
Authors: Saparov К. , Shakhantayeva Zh. , Yeginbayeva A.
Published: August 2023

A large number of natural and artificial water sources are found on the territory of Zhambyl region. This is due to the fact that in the territory located in the mountainous region, the names of rivers, lakes, streams, wells with rich reserves of water resources are often found, and the nature of hydrological objects is clearly indicated. It can be said that the terms defining geographical names that characterize natural water sources have an ecological and geographical basis. Natural water sources have played an important role in the economy and provide extensive geographical information from history. From modern historical and archaeological data it can be seen that the first human settlements were located near water bodies. The article analyzes specific data on the manifestations, formation and features of the names of artificial and natural water sources in the study of microhydrogems of the Zhambyl region. The names of water bodies (hydronyms) are based on hydrographic terms. With the help of the terms contained in the hydronyms, it is possible to determine the type, nature and geographical features of water bodies. Toponymic analysis, geoinformation methods of differentiation and drawing conclusions were used in the study of microhydronyms of Zhambyl region.
Quimioterapia Primária em Carcinoma Avançado de Cabeça e Pescoço
Authors: Oliveira Filho Juvenal Antunes de , Cunha Fernando Medina da , Schlupp Werner Roedel , Chiminazzo Junior Honório , Cunha Ludmilla Medina da
Published: August 2023

Os autores relatam os resultados de um estudo piloto de quimioterapia primária com associação de Cisplatina e Bieomicina ambulatórial no câncer avançado de cabeça e pescoço. Após 2 ciclos de quimioterapia, os pacientes foram encaminhados para radioterapia. Dos 46 pacientes que receberam inicialmente a quimioterapia, 34,7% tiveram resposta objetiva, com sobrevida estatisticamente maior em relação aos que não responderam, mediana de 28 e 13 meses respectivamente (p = 0,0031). Após a radioterapia a taxa de resposta objetiva subiu para 63,6% com sobrevida mediana de 28 meses para os que responderam e de 8 meses para os que não responderam (p = 0,027). A conclusão foi de que os carcinomas epidermóides da cabeça e pescoço são tumores sensíveis à quimioterapia como tratamento primário, justificando-se estudos prospectivos e randomizados.
Pediatric Brain Stem Tumors: Analysis of 25 Cases
Authors: Pinel M. Izabel S. , Kalifa C. , Sarrazin D. , Lemerle J.
Published: August 2023

The charts of twenty-five pediatria patients with brain stem tumors diagnosed between March 1977 and December 1980 have been reviewed. Ages of patients ranged from 22 months to 17 years. The use of computed tomography (CT) was found to have been valuable in diagnosis and follow-up, as well as in the design of radiation therapy portals. Radiotherapy and combination chemotherapy with VM26 (4'-1 demethyl-epipodophyllo-toxin B-D-thenyUdene glucoside) and CCNU (1-2-chloroethyl-methyl-3-Cyclohexyl-1-nitrosourea) were the treatment modalities employed. The three-year survival rate for this group of patients was 29%.
Estudo das Reações Emocionais e Grau de Informação sobre a Doença em uma População de Pacientes com Câncer no Rio Grande do Sul – Brasil
Authors: Schwartsmann Gilberto , Eizirik Cláudio Laks , Kauffmann Ana Luiza , Maltiz Flávia Friedman , Amaral Liliana Ramos do , Soibelman Mauro , Menezes Vânia Gomes de , Day Vivian Peres
Published: August 2023

Os autores apresentam os resultados de um estudo envolvendo uma população de 56 pacientes oncológicos atendidos na Central de Oncologia (C.O.) do Instituto Nacional de Assistência Médica e Previdência Social (INAMPS) em Porto Alegre - RS. durante o período de fevereiro a setembro de 1984. As reações emocionais frente à doença, o grau de informação dos pacientes e os sentimentos despertados nos autores são discutidos neste trabalho.
O Tratamento do Câncer com Interleucina-2
Authors: Rumjaneck Vivian M.
Published: August 2023

Artigo de opinião de Vivian Rumjaneck, do Instituto Nacional de Câncer (INCA), sobre imunoterapia como forma de tratamento contra o câncer, com lnterleucina-2.
Osteoartropatia Hipertrofica Associada a Carcinoma Mucoepidermóide da Glândula Parôtida
Authors: Costa Mario Alberto Dantas L. da , Mendonça Nilson Soares P. de , Froimtchuk Miguel J. , Allan Sérgio E.
Published: August 2023

A osteoartropatia hipertrófica tem sido mais freqüentemente associada a câncer de pulmão. Raramente tem sido relacionada a doença metastática pulmonar, especialmente em osteossarcomas, sarcomas de partes moles, tumores do nasofaringe e uterinos. Os autores relatam o primeiro caso de uma síndrome de osteoartropatia relacionada a um carcinoma mucoepidermóide da glândula parótida metastático para pulmão. A evidência desta síndrome sugeriu a presença de patologia intratorácica. A ressecção de múltiplos nódulos pulmonares trouxe alívio transitório dos sintomas.
Quimioterapia com Cisplatinum, Vinblastina e Bleomicina (PVB) em Pacientes Portadores de Tumores Germinativos Avançados do Testiculo
Authors: Moreira Wagner Brant , Brandão Eduardo Carvalho , Nascimento Eduardo , Lopes Eugênio Baumgratz , Teixeira João Augusto M. , Vieira Maria do Carmo L. R. , Alvares Maria Nunes , Cabral Filho Sebastião
Published: August 2023

Vinte e oito pacientes portadores de tumores germinativos do testículo foram tratados com Cisplatinum, Vinblastina e Bleomicina e observados por um período mediano de 33,5 meses. Remissão completa (RC) com quimioterapia isolada foi obtida em 13/28 (43%). Outros 4 entraram em remissão completa com a associação de quimioterapia e cirurgia, perfazendo um total de 16/28 (57%) de pacientes livres de doença. Nos pacientes considerados como portadores de doença mínima encontramos 6/7 (86%) em RC, sendo que não houve nenhuma recidiva neste grupo de pacientes. Naqueles considerados como portadores de doença avançada encontramos 10/21 (47,6%) em RC sendo que apenas cinco permaneceram continuamente sem evidências de doença e um deles foi resgatado com um esquema de segunda linha. O PVB foi bem tolerado e é muito eficaz nos pacientes portadores de doença mínima. No entanto, nos pacientes com doença avançada apenas 24% obtiveram uma remissão completa prolongada e provavelmente a cura. A curva de sobrevida calculada pelo método de Kaplan-Meier revelou sobrevida mediana de 36.6 meses e sobrevida a 4 anos de 48% dos pacientes.
Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes
Authors: Faria Sérgio Luis , Murtinho Regina Maciel
Published: August 2023

A Doença de Hodgkin representa um terço dos linfomas malignos. É um dos cânceres mais curáveis hoje, com a utilização da radioterapia e quimioterapia adequadas Estes tratamentos, apesar de oferecerem alto índice de cura, podem causar complicações importantes como esterilidade ou nova neoplasia. É responsabilidade de quem trata pacientes com Linfoma de Hodgkin obter ótimo índice de controle tumoral com baixo índice de complicações, e este objetivo n50 é fácil. No presente trabalho analisamos 61 casos de pacientes adultos com Doença de Hodgkin, tratados no Centro de Oncologia Campinas, de janeiro de 1978 a julho de 1985. Em relação ao estadiamento 16 eram estádio 1, 21 eram 11, 20 eram III e 4 eram IV. A sobrevida global foi de 9210 9 e a sobrevida livre de doença foi de 75%, em cinco anos O tempo médio de seguimento foi de 36 meses. Na fase 9 de avaliação de extensão de doença, houve algumas dificuldades ligadas à nossa deficitária medicina social ainda em desenvolvimento, mas que não repercutiu no controle da neoplasia. Em dois terços dos casos, que puderam ter uma avaliação da função gonadal, não houve alteração menstrual ou azoospermia a longo prazo devidos aos tratamentos. Houve apenas um caso de segunda neoplasia, provavelmente não relacionada com os tratamentos previamente recebidos pela paciente, mas como estas complicações tumorais aparecem tardiamente é necessário maior seguimento.
Xeroderma Pigmentosum: Relato de Dois Casos
Authors: Herter Liliane D. , Herter Nilton T. , Godoy Paulo Roberto Ferreira , Heller Nelson , Steffen Níveo , Hartmann Rosaura , Luswanberg Milton Luis
Published: August 2023

O Xeroderma pigmentosum é uma doença grave, rara e hereditária. Seu diagnóstico é essencialmente clínico e, até o momento, não há uma terapêutica totalmente eficaz para a doença básica. Baseados nisso, os autores revisam na literatura a etiologia, etiopatogenia e patologia desta doença. A seguir, relatam dois casos clínicos tratados no Hospital Santa Rita da Associação Sulriograndense de Combate ao Câncer, enfatizando o tratamento clínico e cirúrgico da doença básica e suas lesões pré-cancerosas e cancerosas.
Nefrotoxicidade da Cisplatina
Authors: Broecker Neto Adalberto , Lago Sérgio , Radke Rodolfo Coutinho , Costa Ailzo José da , Kalil Nelson Gustavo M.
Published: August 2023

Duzentos e noventa e dois pacientes receberam 1. 106 cursos de Cisplatina (DDP) com uma nefrotoxicidade de 9,7% (7,9% leve, 1,6% moderada e 0,2% grave. Duzentos e três pacientes (757 cursos) foram tratados exclusívamente a nível ambulatorial, com um método de administração do DDP sem hidratação prévia e em infusão de três horas. A toxicidade renal observada foi de 10, 1% (8,4% leve, 1,4% moderada e 0,2% grave). Todos os pacientes foram avaliados em relação à presença de alterações renais prévias, métodos de administração do DDP, localização do tumor primário, dose administrada por curso, esquema de administração do DDP e dose cumulativa. O fator mais importante no desenvolvimento de maior nefrotoxicidade com o uso de DDP é a presença de alteração renal prévia (p <0,0001). Não foram encontradas relações entre nefrotoxicidade e métodos de administração da droga, localização dos tumores primários, doses por curso, esquemas de administração do DDP e doses cumulativas. O método de administração do DDP em ambulatório sem hidratação prévia é seguro e apresenta toxicidade renal clinicamente aceitável.
Tratamento Combinado nos Tumores Avançados do Rinofaringe
Authors: Souhami Luis , Rabinowits Milton , Rodrigues Antonio Tadeu
Published: August 2023

No período entre outubro de 1982 e agosto de 1984, 30 pacientes com carcinoma epidermóide do rinofaringe, estádios III (26,51) e / V (73,5%), receberam uma combinação de radioterapia (6.500 a 7. 000cGy /7a 7,5 semanas) e quimioterapia com 5-Fluorouracil (750mg/m2, por infusão contínua, dias 2 a 4), Mitomicina-C (10mg/m2, endovenoso, dia 1) e Methotrexate (30mg/m2, endovenoso, dia 1). A idade mediana foi de 40 anos e 20 pacientes eram do sexo masculino. Linfoepitelioma foi diagnosticado em 66,5% dos casos O seguimento mínimo foi de 24 meses. As sobrevidas global e livre de doença em 48 meses foram de 49% e 35%, respectivamente. Dos 28 pacientes avaliáveis, 75110 obtiveram resposta local completa. O índice de recidiva local foi de 9,5%. Falha à distância foi observada em 31% dos casos. O número de complicações foi alta e incluiu mucosite (grave em 52%), xerostomia, infecção (dois casos fatais de septicemia). Apesar da alta taxa de respostas completas obtidas, a pouca influência que isso exerceu na curva de sobrevida e o número elevado de complicações nos levam a contra-indicar a terapia combinada como tratamento de rotina nesses tumores. Um estudo randomizado é necessário para estabelecer essa questão.
Aspectos Qualitativos da Reabilitação de Pacientes Laringectomizados
Authors: Helsinger Frida M Horovitz , Seif Célia Schwarzs
Published: August 2023

O presente trabalho visa apresentar os resultados obtidos na pesquisa realizada no Instituto Nacional de Câncer - RJ, para verificar fatores que influenciam na reabilitação de pacientes submetidos à laringectomia total. Tal objetivo deve-se, por um lado, à compreensão de que a cirurgia desencadeia, além da perda da fala, reações psicológicas que necessitam de assistência adequada dirigida para a posterior adaptação do paciente à sua nova condição. Por outro, deve-se a observações empíricas, colhidas através da assistência psicológica, que demonstraram a existência de um grupo de fatores que podem servir como indicadores prévios da futura reabilitação dos pacientes. Pretende, portanto, responder às questões referentes à possibilidade de planejamento terapêutico e preventivo, facilitadores da obtenção de resultados positivos na assistência global prestada aos pacientes e indicar dados precisos que possam contribuir para a avaliação da qualidade de vida posterior ao tratamento.
Anticorpos Monoclonais em Câncer
Authors: Lopes José Daniel
Published: August 2023

Artigo de opinião de José Daniel Lopes, Pesquisador Sênior do Instituto Ludwig de Pesquisa Sobre o Câncer, sobre anticorpos monoclonais em câncer
Mathematics Mobile Game Visual Asset Design
Authors: Nathaniel Andreatono , Yahya Saiful
Published: August 2023

Mathematics is one of the compulsory subjects for students in Indonesia.  Mathematics is one of the quality of learning subjects, especially math during the epidemic seoson, the learning materials are effective, interesting ang not boring for students.  One  way is to create educational games using mobile phones.  Educational game is an Android based mobile game that makes it easier for users to use it anywhere and anytime than other platforms, same as a computer.  Therefore, the problem posed in this research is How to generate mathematical mobile game image assets? Solution to this research problem is how to design visual assets with a natural theme.  So create some icons, buttins and background design with forest design, wood design and another math related objects.  It is then incorporated into the final design.  End of the result from this research is visual game assets can be used to make games easy to operated and enjoyable, especially for elementary student in grades 3 and below.
Perancangan Cergam Pesta Paskah Sebagai Media Interaktif Untuk Anak Sekolah Minggu
Authors: Ashari Alhadid Lutfi , Sarjono Sarjono , Kurniawan Rahmat
Published: August 2023

Dalam perayaan Paskah terdapat pula kegiatan untuk anak anak, dimana anak-anak melakukan kegiatan berdoa, memainkan drama, menghias telur Paskah, dan juga mendengarkan khotbah ringan. Namun biasanya saat memberikan khotbah ke pada anak, anak sering sekali merasa jenuh, bosan dan tak jarang juga ada yang bermain sendiri saat khotbah berlangsung. Maka berawal dari permasalahan itu dirancangnya perancangan cergam ini sebagai media pendukung saat khotbah, di dalam perancangan ini anak tidak hanya mendengarkan dan melihat tetapi anak juga dapat berinteraksi langsung dalam kegiatan yang ada di perancangan buku cergam ini. Metode yang digunakan dalam perancangan ini ialah milik Drs. Sadjiman Ebdi Sanyoto. Teknik pengumpulan data berupa wawancara dan observasi. Dengan hasil analisis menggunakan analisis 5W+1H sebagai analisis data. Hasil Akhir perancangan buku cergam Paskah ini memiliki media pendukung utama yaitu berupa buku cergam dengan ukuran A4 dengan jumlah 34 halaman dan boneka tangan sebagai merchandise, menggunakan hard cover sebagai cover, dicetak pada kertas art paper ukuran 260 full color, terdapat kartu magnetic sebagian media pendukung dalam memberikan materi yang ada di buku cergam ini dan memiliki 5 kegiatan dalam 1 buku.
PENGAMATAN PERTUMBUHAN DAN PERKEMBANGAN KUPU-KUPU JENIS GRAPHIUM AGAMEMNON TERHADAP TANAMAN INANG DI KETAMBE (PENANGKARAN KUPU-KUPU KETAMBE) KABUPATEN ACEH TENGGARA SEBAGAI MEDIA PEMBELAJARAN EKOLOGI HEWAN
Authors: Almukarramah  , Fitri Ramadani  , Ibrahim  , Azwir  , Nurul Akmal
Published: August 2023

Spesies kupu-kupu memiliki kelompok spesifik dalam satu tumbuhan tertentu, yang dapat dijadikan sebagai tumbuhan inang. Graphium agamemnon merupakan jenis kupu-kupu yang masuk dalam ordo lepidopttera famili papilionidae, jenis kupu-kupu memiliki kandungan mineral yang sangat tinggi. Menyerap mineral yang kemudian mampu mengeluarkan kembali airnya ke dalam tanah sehingga membantu untuk melarutkan mineral. Kemudian kupu-kupu yang memiliki peran penting dalam penyerbukan tanaman berbunga yang berada dalam sekitaran pada penangkaran kupu-kupu Ketambe Kabupaten Aceh Tenggara. Berdasarkan masalah tersebut di atas penelitian ini akan terfokus pada bagaimana pengamatan pertumbuhan dan perkembangan kupu-kupu jenis Graphium agamemnon terhadap tanaman inang penangkaran Ketambe Kabupaten Aceh Tenggara. Adapun jenis penelitian yang dipakai adalah jenis penelitian lapangan (field research) yang bersifat kualitatif serta menggunakan pendekatan model deskriptif. Adapun hasil di penelitian ini adalah kupu-kupu jenis Graphium agamemnon melakukan aktifitas sepanjang hari dimulai pukul 08.00 sampai pada pukul 16.00 WIB kupu-kupu memanfaatkan tanaman inang beserta area sekitarnya sebagai lokasi untuk ia terbang dan dalam daun-daun muda inang ini digunakan oleh kupu-kupu betina sebagai media tempat penempatan semua telurnya, sedangkan stadium larva kupu-kupu ini bisa memanfaatkan daun tanaman inang sebagai pakannya.

Kata Kunci : Kupu-Kupu Jenis Graphium Agamemnon dan Tanaman Inang
PENGARUH EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) TERHADAP GAMBARAN HISTOPATOLOGI GINJAL YANG DIINDUKSI STZ (Streptozocin) TIKUS PUTIH (Rattus norvegicus)
Authors: Ulfa Tunnur  , Jailani  , Nurlena Andalia  , Nurul Akmal
Published: August 2023

Tujuan penelitian ini untuk mengetahui apakah ada pengaruh ekstrak etanol daun kersen (Muntingia calabura l.) terhadap gambaran histopatologi ginjal yang diinduksi stz (streptozocin) tikus putih (Rattus norvegicus) diabetes mellitus. pendekatan dalam penelitian ini adalah pendekatan kualitatif dengan jenis penelitian deskriptif, dan eksperimen dengan metode Rancangan Acak Lengkap (RAL) dengan 5 kelompok dan 3 kali pengulangan. Penelitian ini dilakukan pada tanggal 08-22 Mai 2023. Objek dalam penelitian ini adalah 30 ekor tikus putih (Rattus norvegicus) yang sudah diinduksi streptozocin untuk diabetes mellitus. Analisis data dilakukan dengan pengamatan pada gambar histopatologi ginjal Tikus Putih (Rattus norvegicus), melalui mikroskop cahaya olympus. Hasil yang diperoleh dari penelitian ini bahwa, pada K1 (pemberian larutan aquades), terlihat sel epitel tubulus tampak normal. Pada K2 (diinduksi streptozocin 30 mg / kg BB), sel epitel tubulus mengalami nekrosis dengan inti sel piknotik, perlebaran lumen tubulus, hemoragi yang berat.Pada K3 (diinduksi streptozocin 30 mg/kgBB dan pemberian obat metformin), terlihat sedikit sel epitel tubulus mengalami nekrosis, dan kongesti.Pada K4 (diinduksi streptozocin 30 mg/kgBB dan ekstrak daun kersen 10%), terdapat beberapa sel epitel tubulus mengalami nekrosis dengan sitoplasma terlihat lisis.Sementara pada K5 (diinduksi streptozocin 30 mg/kgBB dan diberikan ekstrak etanol daun kersen 15%),menghasilkan sel epitel tubulus berbentuk normal tidak ditemukan nekrosis sel epitel tubulus dan degenerasi sel lemak. Dengan demikian ekstrak etanol daun kersen (Muntingia calabura l.), yang berdosis 15%, efektif dalam menurunkan kadar glukosa darah dan memperbaiki kerusakan sel di dalam tubuh akibat dari zat tosik STZ (Streptozocin).

 

Kata Kunci: daun kersen (Muntingia calabura l.), histopatologi ginjal tikus putih, streptozocin
HUBUNGAN BERPIKIR POSITIF DENGAN STRES AKADEMIK SISWA SMA X DI SIDOARJO
Authors: Nashrullah Mochamad , Fahmawati Zaki Nur
Published: August 2023

Penelitian ini dilatar belakangi oleh adanya fenomena stres akademik yang dialami oleh siswa SMA X Pada Masa Pandemi Covid-19. Penelitian ini bertujuan untuk mengetahui hubungan antara berpikir positif dengan stres akademik pada siswa SMA X. Penelitian ini termasuk jenis penelitian kuantitatif dengan pendekatan korelasional. Penelitian ini dilakukan di SMA X. Populasi dalam penelitian ini berjumlah 1.658 siswa, sehingga dari perhitungan menggunakan metode krejcie dan morgan sampel yang digunakan sebanyak 310 siswa yang diambil dengan menggunakan teknik stratified random sampling. Pengumpulan data dalam penelitian ini menggunakan dua skala psikologi yaitu skala berpikir positif dan skala stres akademik. Analisis data dalam penelitian ini menggunakan Spearman’s rho Correlations dan proses analisa ini menggunakan bantuan program JASP versi 0.13.1.0 for windows. Hasil penelitian didapatkan nilai r = -0.480 dan nilai p = 0,001 dimana 0,001 < 0,05 yang artinya ada hubungan negatif yang signifikan antara variabel berpikir positif dengan stres akademik pada siswa SMA X. Pengaruh berpikir positif terhadap stres akademik sebesar 33,1 %.
PENGGUNAAN METODE DISCOVERY LEARNING DALAM PENINGKATAN HASIL BELAJAR MATERI GEOMETRI SISWA SMP
Authors: Murni, Ph.D  , Manovri Yeni  , Muhammad Daud  , Muhamad Saleh
Published: August 2023

Matematika adalah salah satu disiplin ilmu yang diajarkan di sekolah, namun sampai saat ini matematika termasuk salah satu pelajaran yang kurang diperhatikan siswa. Metode discovery bersifat yaitu guru harus menstimulir siswa untuk berfikir aktif, menjaga berkembangnya suasana bebas dan mendorong siswa untuk berani mengeluarkan buah fikiran sendiri. Penelitian ini bertujuan untuk:  Untuk mengetahui perbedaan hasil belajar siswa yang diajarkan dengan metode discovery dibandingkan dengan metode konvensional. Pendekatan dan Jenis Penelitian adalah pendekatan kuantitatif dengan mengambil jenis penelitian Eksperimen. Penelitian ini dilaksanakan pada Sekolah Menengah Pertama Swasta Islam Kuala Simpang. Adapun yang menjadi sampel yaitu kelas IX2 yang berjumlah 24 siswa sebagai kelas eksperimen dan kelas IX3 sebanyak 30 siswa sebagai kelas kontrol. Sampel diambil dari dua kelas tersebut secara porposif ramdom sampling. Kesimpulan dari penelitian ini menunjukkan bahwa: 1) Hasil belajar matematika siswa yang diajarkan dengan menggunakan metode discovery lebih baik jika dibandingkan dengan prestasi belajar matematika siswa yang menggunakan metode konvensional, 2) Hasil belajar matematika siswa dapat dilihat dari perolehan nilai rata-rata pada pokok bahasan geometri, dimana untuk kelompok eksperimen (kelas IX2) nilai rata-ratanya adalah 72,17 sedangkan untuk kelompok kontrol (kelas IX3) adalah 56,9.
HUBUNGAN ANTARA PENDIDIKAN GURU DALAM JABATAN DENGAN KINERJA GURU DI MAS AL- ISHLAH AL- AZIZIYAH BANDA ACEH
Authors: Anwar Anwar , Zakaria  , Nazarina Rahmi , Abubakar  , Israwati  , Lisa Agustina
Published: August 2023

Penelitin ini bertujuan: 1) Untuk mengetahui bentuk kegiatan pendidikan guru dalam jabatan di Mas Al-Ishlah Al-Aziziyah Banda Aceh: 2) Untuk mengetaui kinerja guru di Mas Al-Ishlah Al-Aziziyah Banda Aceh. 3) Untuk mengetahui hubungan antara pendidikan guru dalam jabatan dengan kinerja guru di Mas Al-Ishlah Al-Aziziyah Banda Aceh. Populasi dalam penelitian ini adalah 21 orang.  Menggigat jumlah populasi tidak terlalu besar maka semua populasi dijadikan sampel. Teknik pengumpulan  data  dalam  penelitian  ini yaitu  observasi,  wawancara  dan  angket.  Teknik analisis  data  mengunakan analisis regresi linear  sederhana. Hasil penelitian ini adalah : 1) Bentuk kegiatan pendidikan guru dalam jabatan di Mas Al-Ishlah Al-Aziziyah Banda Aceh adalah mengikuti  seminar  yang  berkaitan  dengan  bidang  profesinya,  mengikuti  penulisan  karya ilmiah  yang diadakan  oleh  pihak  sekolah  maupun  dinas  pendidikan,  mengikuti  pelatihan penggunaan computer, mengikuti MGMP, mengikuti lokakarya, penataran kurikulum 2013, menerima supervisi dari atasan, mengadakan diskusi membahas tentang cara mengajar dengan teman  sejawat,  mengikuti  sertifikasi   yang  diadakan  oleh  pemerintah, dan mengikuti pendidikan yang lebih tingi: 2) Berdasarkan nilai kinerja guru yang diperoleh  4,4 maka dapat di simpulkan bahwa kinerja guru Mas al-ishlah al-aziziyah banda aceh adalah sangat baik:  3) tidak adanya hubungan yang signifikan antara variabel pendidikan guru dalam jabatan (x) dengan kinerja guru di Mas Al-Ishlah Al-Aziziyah Banda Aceh (y).hal ini dibuktikan dari hasil perhitungan nilai t hitung lebih besar dari t tabel (0.6>0.1)
O sentido da vida e sua relação com as religiões, o corpo e as enfermidades
Authors: Sousa Marcel Alcleante Alexandre de
Published: August 2023

Este artigo fundamenta-se em escritos já publicados sobre corpo, religião e relatos do lidar com enfermidades. Essa relação evidencia o corpo como uma expressão cultural, envolvendo aspectos biológicos, sociais, psíquicos e espirituais dentro de memórias e práticas. Essa abordagem enfatiza as práticas religiosas diante do sofrimento que as enfermidades proporcionam. Verificou-se que o papel da religião está em apresentar um sentido ao bem viver e não condenação e afirmação de castigo pela enfermidade. As bibliografias levantadas apontam que em momentos de crises e enfermidades, o corpo é ressignificado pela devoção. Assim, a religião busca oferecer formas de lidar com o sofrimento e estabelecer conexões com o transcendente.
Os direitos de personalidade, direito à vida e o consentimento informado nos procedimentos médicos
Authors: Frazão Erica Islândia dos Santos Fragoso
Published: August 2023

O direito à vida e o consentimento informado nos procedimentos médicos asseguram o direito à integridade física e psicológica dos pacientes. Os profissionais de saúde reforçam a sua confiança a partir da consciência que ganham em relação à nova era, em que a aplicação de seus conhecimentos permite não só desvelar a dimensão técnica como também psicoemocional, obtendo o consentimento informado e esclarecido do paciente, que, no conjunto, configuram o respeito à ordem jurídica nesta matéria. Este artigo tem como objectivo descrever os direitos de personalidade e o consentimento informado nos procedimentos médicos, garantindo, assim, o bem-estar dos pacientes e uma maior confiança na relação médico-paciente. Face ao explanado, suscita-se o seguinte questionamento: como os procedimentos médicos devem ser aplicados para que não violem os direitos de personalidade dos pacientes? Trata-se de um trabalho de natureza qualitativa, de carácter exploratório e essencialmente bibliográfico que visa suportar os objectivos do estudo. A metodologia aplicada foi o método descritivo, que permitiu descrever e demonstrar como um determinado procedimento ocorre e quais são as suas características e relações com outros procedimentos, tendo como foco o consentimento informado nos procedimentos médicos, garantindo o bem-estar dos pacientes e um maior reforço na confiança da relação médico-paciente. Espera-se que este trabalho permita despertar a consciência no legislador angolano, no sentido de suprir a lacuna em termo de suporte legislativo e, como resultado, permita criar uma legislação complementar específica sobre essas matérias para o bom funcionamento da actividade dos profissionais, não obstante existirem algumas normas que podem solucionar uma determinada situação oriunda da colisão de direitos, como pode-se ver na Lei Magna da Constituição da República de Angola (CRA), 2010, no Código Penal Angola, 2020, na Lei nº 20/19 (Lei sobre o Transplante de Células, Tecidos e Órgãos Humanos), bem como na Lei nº 21-B/92 (Lei de Bases do Sistema de Saúde Nacional).
PROBLEMS OF HUMAN POTENTIAL PRESERVING IN UKRAINE IN THE CONDITIONS OF WAR
Authors: Tomchuk Olesya
Published: August 2023

The peculiarities of human potential as a specific object of socio-economic management in the conditions of war are determined. Separate types of direct and indirect losses of Ukraine's human potential as a result of the full-scale invasion of russia are analyzed, which determine the actual problems of its preservation for the future recovery of the economy. A classification of the problems of preserving human potential in the conditions of war has been made, which will allow differential introduction of management tools in relation to different types of problems in the field of labor and human potential. The basic stages of the algorithm of the human potential preservation in Ukraine in war conditions are proposed.