bluuebunny/crossref_metadata_2025 huggingface dataset:
Aristolochia of Siphisia section in vitro
Authors: Nakonechnaya О. V. , Gafitskaya I. V. , Yusupova Е. P.
Published: December 2024

The results of the study represent an optimization protocol for clonal micropropagation of 4 species of the genus Aristolochia, Siphisia section. Plants of these species are rare, endemic and medicinal plants. 6-Benzylaminopurine (BAP) (0.5, 1.0, 1.2 and 1.4 mg/L) and indolylbutyric acid (IBA) (0.5 and 1.0 mg/L) were used in this work. The use of subcultivation with different nutrient media (MS supplemented with 0.5 mg/l BAP at the propagation stage and ½ WPM with the addition of 0.5 mg/l IBA at the rooting stage) contributes to the mass production of microplants. The maximum values of the microshoot height for each species were detected on the medium with 0.5 mg/l BAP. Explants of A. macrophylla and A. manshuriensis were characterized with the greatest reproduction coefficient (34 pcs.); while A. californica explants displayed the least coefficient (18.6 pcs.). The difference is associated with the activation of a different number of buds in each species.
The relationship of quantitative indicators sCD56 and sCD16 with the level of immunocompetent cells, cytokines, circulating immune complexes and cyclic nucleotides in practically healthy people living in the Arctic territory
Authors: Samodova A. V. , Dobrodeeva L. K. , Patrakeeva V. P.
Published: December 2024

We studied the content of immunocompetent blood cells, phagocytic activity of neutrophils, concentrations of cytokines, circulating immune complexes and levels of cyclic nucleotides (cAMP and cGMP) of serum with different levels of soluble adhesion molecules NCAM (CD56) and immunoglobulin Fc-receptor III (CD16) in practically healthy people living in the Arctic territory. It was found that the increase in serum concentration of sCD56 and sCD16 in practically healthy adults of working age is associated with an increase in the content of cells with the corresponding membrane receptors. The increase in sCD56 concentration occurs with an increase in the content of NK cells (CD3-CD16+CD56+) and T-NK cells (CD3+CD16+CD56+). The increase in sCD16 level is accompanied by a decrease in the content of circulating in the blood lymphocytes predominantly T-helper cells (CD3+CD4+), cytotoxic T-lymphocytes (CD3+CD8+) and activated T-lymphocytes (CD3+HLADR+). Increased sCD56 concentrations were associated with increases in pro-inflammatory IL-1β, IL-6, TNF-α and anti-inflammatory IL-10. Concentrations of circulating immune complexes increased with increasing sCD16 and sCD56 content. The signal conduction activity increases with increasing content of CD16+ and CD56+ leukocytes of peripheral blood and sCD56+ leukocytes and shedding of these molecules occurs against the background of decreasing concentrations of cAMP and cGMP.
Habitat suitability and areal dynamics of rare desert species of myxomycetes of the genus Didymium under global climate change in Asia
Authors: Vlasenko A. V. , Vlasenko V. A.
Published: December 2024

The ability to determine the spatial distribution of rare species is critical to understanding the environmental factors that influence them. Maximum entropy (MaxEnt) modeling of spatial distributions addresses this problem by allowing inferences about species distributions under environmental change from occurrence data. Using this method, we mapped the current and potential geographic distribution of two rare species of desert myxomycetes, Didymium mexicanum and Didymium nullifilum. Models of potential global species distributions were created using bioclimatic data and MaxEnt software to model species habitat suitability under current conditions (~1950–2000) and under projected changes in future climate (2100 AD) based on 18 spatial distribution points for D. mexicanum and 4 points for D. nullifilum. A detailed morphological description is given for the species. We identified the species D. mexicanum for the first time in Asia.
Highly Productive Soft Spring Wheat Kinelskaya Udacha Variety for Forest-Steppe Conditions of the Middle Volga and Ural Regions
Authors: Demina E. A. , Taranova T. Yu. , Romenskaya S. E. , Kincharov A. I.
Published: December 2024

The results of breeding work on the creation of a new variety of soft spring wheat Kinelskaya Udacha are presented. The research was conducted in 2019–2023 in the forest-steppe zone of the Samara region. The weather conditions of the vegetation were diverse, but in general they were quite arid: the hydrothermal moisture coefficient in 2019 was 0.48, 2020 – 0.52, 2021 – 0.39, 2022 – 0.62, 2023 – 0.41, the average annual norm was 0.73. The selection work was carried out according to the Methodology of the state variety testing. The comparison of the new variety was carried out with the Tulaykovskaya Nadezhda standard and the zoned Kinelskaya Yubileynaya variety. The Kinelskaya Udacha variety showed a consistently high grain yield over the years of research of 2.24–4.34 t/ha (on average 3.19 t/ha), the average increase over the Tulaykovskaya Nadezhda standard was 0.37 t/ha (13.1%), over the Kinelskaya Yubileynaya variety – 0.12 t/ha (3.9%). The adaptability of the new variety is 106.1%, which is 12.7% higher than the standard and the Kinelskaya Yubileynaya variety by 3.9%. Productive bushiness is high, on average 2.0 pcs. (the standard has 1.6 pcs.). It was characterized by consistently high flour strength of 353...503 e.a. (on average 412 e.a.), high grain size of 811–848 g/l (on average 823 g/l), and high gluten content in grain of 26.8–33.6% (on average 28.5%) of the second quality group (in an average of 87 units. IDK). The protein content in the grain is 13.4–15.9% (average 14.2%). The overall baking grade is high – 4.4 points. It has complex resistance to pathogens and high drought resistance (5 points), resistant to lodging (4.3 points), grain shedding (5 points) and its germination on the root (5 points). It is designed for the production of high-quality food grains. The variety has been undergoing State testing in the Middle Volga and Ural regions of the Russian Federation since 2024.
Adaptive Potential of Seed Crops on the Example of Apple Tree Varieties and Quince Seedlings
Authors: Galasheva А. М. , Semin I. V. , Ozherelyeva Z. Е.
Published: December 2024

Apple is the main fruit crop in the European part of Russia. Quince is a promising crop as a valuable low-growing rootstock for pears. The most favorable conditions for growing pome crops (apple and common quince) are in the Central and Central Black Earth regions (Voronezh, Tula, Lipetsk, Kursk, Belgorod, Oryol, Ryazan and Tambov regions). Currently, there is a wide variety of varieties and rootstocks (of various selections) for apple and pear trees, but choosing more adaptive ones for each ecological-geographical zone in intensive gardening is considered relevant. The studies were carried out on the basis of VNIISPK in 2018–2023. Apple cultivars of VNIISPK breeding and foreign cultivars grafted on rootstock 54-118 as well as common quince of VNIISPK breeding selected according to a complex of valuable economically useful characteristics were used as objects of study. The research of the presented work was carried out on the basis of the methodological recommendations “Programs and methods for the variety study of fruit, berry and nut crops” and “Methods for the accelerated assessment of winter hardiness of fruit and berry plants”. Severe frosts occur in the Central region of Russia (Orel region) in winter (January-February). Over the past five years, the lowest air temperature was recorded in the winter of 2020/2021, when in February it dropped to minus 30°C. In the field, the studied apple cultivars on the clone rootstock 54-118 showed sufficient winter hardiness. As a result of freezing of annual branches in laboratory conditions, it was revealed that Ligol (the Polish cultivar) and the VNIISPK cultivars Orlovsky Partizan, Vyatich, Orlovskoe Polesie and Pamyat Semakinu had bud and wood damage according to all I, II, III components of winter hardiness. The most winter-hardy cultivar Rozhdestvenskoe of VNIISPK breeding stood out. In VNIISPK, seedlings of common quince with high winter hardiness of the aboveground and root systems adapted to the climatic conditions of the central part of Russia and possessing restrained growth have been identified. Studies have shown that these quince seedlings being in deep dormancy can withstand frosts up to -36°C and are able to tolerate a decrease in temperature in the zone of the root layer up to -10°C without significant damage.
Assessment of the influence of the metabolitic probiotic Biosib METAPRO on protein metabolism indicators in broiler chickens
Authors: Shvydkov A. N. , Sebezhko O. I. , Kalmykova A. I. , Gulyaeva Yu. A. , Tkachev A. D. , Kozhevnikova P. E. , Alexandrova D. A. , Domnysheva V. V.
Published: December 2024

The paper presents data on the study of the influence of the metabolic probiotic (metaprobiotic) Biosib METAPRO, developed based on a complex of cultures Bifidobacterium longum and Lactobacillus plantarum at LLC “Sibbiopharm”, on the indicators of protein metabolism in broiler chickens. The study was conducted on Ross 308 cross chickens from 6 days to 35 days of age, using four groups: control and three experimental groups, to which Biosib METAPRO was additionally administered in different doses. The quantitative assessment of protein metabolism indicators in the blood serum of birds was performed photometrically using Vector-Best reagent kits. It was established that the levels of total protein, albumin, globulin, albumin/globulin ratio, alanine aminotransferase (ALT), aspartate aminotransferase (AST), de Ritis coefficient, and creatinine in broiler chickens were within the generally accepted physiological norms for birds of this age or showed insignificant deviations. Statistical analysis revealed a significant influence of the metaprobiotic on total protein, A/G ratio, ALT, AST, de Ritis coefficient, and creatinine. The most pronounced changes were observed in chickens receiving Biosib METAPRO at a dose of 0.05%. The greatest number of differences was found between the control and the 1st experimental (Biosib METAPRO at a dose of 0.05%) groups. When administering the preparation at this dosage to broiler chickens, the level of total protein increases by 9.97 g/l, there is a change in A/G ratio, an increase in ALT activity by 1.32 mmol/l⋅h, a decrease in AST by 3.76 mmol/l⋅h, normalization of the de Ritis coefficient, and an increase in the level of creatinine by 13.2 µmol/l (p0.05). The results of the study demonstrate the positive influence of the metabolic probiotic Biosib METAPRO on protein metabolism in broiler chickens, which may contribute to increasing the efficiency and sustainability of poultry meat production.
The Potential of Probiotics from West Sumatra, Indonesia on Low-Density Lipoprotein and Interleukin-6 Levels with Dyslipidemia
Authors: Ridwan Rhinie Uphita , Putranto Wachid , Nuhriwangsa Adi Magna Patriadi
Published: December 2024

Dyslipidemia is a lipid metabolism disorder characterized by abnormal elevations or reductions in one or more lipid fractions within the plasma. This condition is a critical component of both metabolic syndrome and cardiovascular disease (CVD). This study aims to see the potential of curd administration on Low-Density Lipoprotein (LDL) and Interleukin-6 (IL-6) levels in dyslipidemia patients. This study is an experimental study with a pre-post test control group design consisting of a control group and a treatment group totaling 42 people taken randomly at the DR Drs M Hatta Bukittinggi Brain Hospital in June and July 2024. In the three groups, LDL and IL-6 examinations were carried out and measured before and after curd for 14 days. Treatment group 1 was given curd as much as 150 grams, treatment group 2 was given curd as much as 200 grams, given 1x a day, and the control group was not given curd. Data analysis was performed using the Wilcoxon statistical test and paired t-test. Results: There was no significant difference in LDL (p=0.360) and IL-6 (p=0.932) levels after giving curd for 14 days. However, there was a decrease in LDL and IL-6 levels after giving curd for 14 days. Conclusion: The results showed that giving curd for 14 days in the treatment group 1 (150gram) and treatment 2 (200gram) can reduce LDL and IL-6 levels. Consuming probiotics for 14 days can reduce LDL and IL-6 levels.
ИНКЛЮЗИВТІ БІЛІМ БЕРУ ЖАҒДАЙЫНДА ОҚУШЫЛАРДЫҢ МАТЕМАТИКА ПӘНІНЕН ОҚУ ЖЕТІСТІКТЕРІН БАҒАЛАУДЫҢ КРИТЕРИЙЛЕРІ
Authors: Әбдіғапбарова А.Б. , Сейтмұратов А.Ж. , Меңліхожаева С.Қ.
Published: December 2024

Бұл мақалада инклюзивті білім беру жағдайында ерекше білім беруге қажеттілігі бар оқушылардың оқу жетістіктерін бағалаудың критерийлері мен тәртібі қарастырылған. Қазіргі уақытта Қазақстанда оқушылардың дамуындағы кемістіктерден туындайтын ерекше білім беру қажеттіліктері тек арнайы мектептерде ғана толық қанағаттандырылады. Олар психологиялық-медициналық-педагогикалық кеңестің қорытындысын алған мектеп жасындағы балалардың жалпы санының 14,2%-ын оқытады және алты мектеп ұсынымдарын алған. Осы санаттағы қалған балалар, сондай-ақ басқа себептерге байланысты оқуда қиындықтары бар мектеп оқушылары, ұйымдастырудың әдістемелік мәселелерінің дайын болмауы себебінен балаларға қажетті психологиялық-педагогикалық қолдау көрсетпейтін жалпы білім беру мектептерінде оқиды. «Инклюзивті білім беру – барлық дискриминация формасына тосқауыл қоятын, оқушының білім алуындағы әртүрлі қажеттіліктері мен алуан түрлілігін есепке ала отырып, сапалы білім беруді қамтамасыз етуге бағытталған, жалпы білім беруді дамытудың үздіксіз процесі». Әлемдік заманауи қоғамдастықта жаңа мәдени норма қалыптастыру, адам арасындағы айырмашылыққа сыйластықпен қарау және әр адамның даралану құқығын, сонымен бірге қоғам тарапынан оның қандай да бір өзгешелігін, білім алу ортасындағы ерекшеліктерін есепке алу және мойындау. Сондықтан да инклюзивті білім беру оқушының оқу процесі барысындағы әртүрлі қажеттіліктері мен мүмкіндіктерін, алуан түрлі ерекшеліктерін мойындаудан басталады. Жоғарыда талданған пікірлердің негізінде көптеген мемлекеттерде ерекше білім беруге сұраныстары бар балалардың қажеттіліктерін бағалаудың және оқыту барысында қолдауды ұйымдастырудың әлеуметтік педагогикалық моделі қалыптасты. Ал, ол біздің еліміздегі білім беру жүйесінде осы күнге дейін сақталып келген медициналық және дефектологиялық модельден түбегейлі ерекшеленеді.
ЖАЛПЫ БІЛІМ БЕРЕТІН МЕКТЕПТЕГІ ФИЗИКА САБАҚТАРЫНДА ОҚУШЫЛАРДЫҢ ТАНЫМДЫҚ БЕЛСЕНДІЛІГІН ДАМЫТУ
Authors: Аутова Г.М.
Published: December 2024

Мақалада физика және әлемтанудың негіздері арқылы оқушылардың танымдық белсенділігін дамуытудың өзекті мәселелері қарастырылады. Егер пән мұғалімі осыны жүзеге асыру үшін тиісті оқыту әдістерін және жабдықталған сыныптарды қолданса, оқушылардың танымдық белсенділігінің дамуы жоғары болады. Мақалада физика курсы және ғаламның негіздері арқылы танымдық іс-әрекетті жетілдіру әдістері талданады. Мұнда жеке тәжірибеге бағытталған контекст тұжырымдамасы эксперименттік жұмыс барысында тексерілген модель негізінде берілген. Физика аспектілері мен ғаламның негіздерін біріктіру ұсынылған. Мектептегі әр оқушының білім дәрежесіне және жеке қабілетіндегі ерекшіліктеріне сәйкес ең тиімді оқыту әдістері мен тәсілдерін қолдану қажеттіліктері ұсынылады.
Ғылым әрқашанда кездесетін қарама-қайшылықтарды шешу арқылы дамығын. Әлемнің құрылымы туралы абстракциялық-теософиялық көзқарастан бастап, іс жүзінде нақтылы дәлелі бар пікірге дейінгі түрлі болжамдарды кездестіруге болады. Оларды мейлінше қарапайым және түсінікті тілмен жеткізу және оқушыларды ғылыми зерттеуге оңтайлы бағыттау танымдық белсенділікті дамытудың тиімді жолдарының бірі. Қабілеті және пәнге деген қызығушылығы жоғары оқушыларды осы мәселелерді шешуге бағыттау олардың ғылыми зерттеу дағдыларын арттыруға, ойлауын тереңдетуге және өзінің ғылыми ой-пікірін қалыптастыруға көмектеседі. Мақалада осы қайшылықтар төңірігіндегі сұрақтар қарастырылады және оларды танымдық белсенділікті дамыту арқылы шешу тәсілдері қарастырылады. Мақалада физика курсының элементар бөлшектерді тану бөліміндегі кейбір теориялық қайшылықтарды зерттеу қарастырылады. Бұл қайшылықтар физикадағы теориялық зерттеулерді жетілдіру үшін маңызды негіздер болып табылады. Аталған теориялық қайшылықтар физикалық заңдылықтардың өзара үйлесімділігін және олардың нақты эксперименттік нәтижелермен сәйкестігін тексеруге мүмкіндік береді. Олар жаңа тәжірибелер мен бақылаулар арқылы шешімін тауып, физикалық әлемді тану белсенділігін арттырады және білімін тереңдетуге мүмкіндік береді.
К ВОПРОСУ О СОВРЕМЕННОЙ МЕТОДИКЕ ПРЕПОДАВАНИЯ ЮРИДИЧЕСКИХ ДИСЦИПЛИН В ВУЗЕ С ПРИМЕНЕНИЕМ ЦИФРОВЫХ ТЕХНОЛОГИЙ
Authors: Егежанова Д.Р. , Майшекина Э.С.
Published: December 2024

В статье рассмотрены вопросы использования и применения современных методов обучения с применением цифровых технологий. Актуальности заслуживают аспекты преподавания юридических дисциплин на основе анализа имеющихся образовательных программ и существующей траектории обучения. В данном исследовании затронуты проблемы оценки влияния масштабов цифровизации  и перехода образовательного процесса в онлайн-пространство. Практико-ориентированное обучение и подготовка будущих юристов возможны благодаря как традиционным методам обучения, так и при помощи усовершенствованных информационных технологий. В этом отношении цифровые технологии обучения юридических дисциплин, несомненно, выполняют важные задачи. Ключевую роль в формировании цифровой грамотности выполняют педагогический опыт, приобретенные цифровые навыки и качественно организованный цифровой инструментарий.
В статье также проведен  теоретический анализ  цифровой грамотности преподавателей, определены компоненты и  ключевые факторы развития. Цифровые технологии и их применение в высшей школе длительное время являются объектом исследования в трудах как зарубежных, так и казахстанских авторов. Появилось много новых научных терминов, таких как цифровая грамотность, цифровая компетенция, цифровой навык, цифровое сознание и др. Овладение цифровой компетентностью - это сложный многоступенчатый процесс, который может начинаться с традиционных основополагающих аспектов образования, переходя к более сложным и продуктивным аспектам цифровой грамотности.
Были проанализированы современные методики и актуальные методы обучения, цифровые образовательные платформы ряда вузов, а также проведен социологический опрос преподавателей-юристов. На основе представленных в статье результатов были сделаны выводы.
ӘСКЕРИ ЛИРИКАНЫ ОҚЫТУ АРҚЫЛЫ ЖАСТАРДЫ ПАТРИОТТЫҚҚА ТӘРБИЕЛЕУ
Authors: Уткелбаев Қ.З. , Тургунбаева Б.А.
Published: December 2024

Мақалада ХХ ғасырдағы қазақ әскери әдебиеті мәселесі ғалымдардың зерттеулерімен салыстырыла отырып зерделенеді.
Зерттеудің теориялық нәтижелерінің маңыздылығы қазақ әскери әдебиеті, әскери лирика және әскери проза туралы ұғымдарды қалыптастырып, ғылыми айналымға түсіруімен, Ауған соғысы тақырыбындағы шығармалардың жанрлық, стильдік және көркемдік-идеялық ерекшеліктерін зерделеумен дәйектеледі.
Сонымен бірге, қазақ әдебиетіндегі әскери шығармаларлдың маңыздылығы мен жастарға берер тағылымдық, тәлім-тәрбиелік маңызы сараланады. Әскер тақырыбындағы шығармалардың жанрлық ерекшелігі айқындалып, мазмұндық тұрғыдан топтастырылады. Әдеби жанр суреткер мұратын жүзеге асырудың басты құралы. Өз шығармасын қай жанрда жазу арқылы оқырманға ой салу қажеттігін ең бірінші таңдайтын да автор. Сондықтан жанр шығарманың идеялық шешімін табудағы мақсатты жүзеге асырушы. Осы ретте Ауған соғысы тақырыбындағы жазылған әдеби туындылардың арасында лирикалық жанрдың ерекше көзге түсетіндігін атап өтуіміз керек.
Зерттеудің жаңалығы – қазақ әдебиетіндегі әскер тақырыбын, әскери лириканы оқыту арқылы білім алушыларды патриоттыққа тәрбиелеу. Әскери шығармалардағы тұлғалық образдар арқылы жастардың бойында ішкі рух пен жігер қалыптастыру, өзін-өзі тәрбиелеуге, тұлғалық болмысын сақтауға үйрету.
Bilateral Ventricular Papillary Muscle Variations - A Morphometric Study
Authors: R. Ambiga , Verma Suman , Patra Dr Ambika Prasad
Published: December 2024

BACKGROUND: Papillary muscles (PM) are vital, especially in cases of atrioventricular (AV) valve prolapse. Bilateral and population-specific variations in PM length are among the several factors that influence the failure of AV valve replacement surgeries. PM morphometric variations between ventricles necessitate a thorough understanding of the effective surgical interventions.

AIM: This study aimed to measure PM variations in the South Indian population to determine appropriate preventive measures, i.e. to compare PM morphometric parameters in both side heart ventricles and correlate the findings with baseline characteristics.

METHODS: This 2-year autopsy-based prospective study involved 171 fresh adult heart samples. The PM was classified by position and measured for length, breadth, and thickness, with the anterior PM being the largest in both.

RESULTS: The study outcomes showed statistically significant and consistent differences in the PM dimensions between the left and right ventricles. The left ventricular anterior PM were longer, broader, and thicker than their right ventricular counterparts (P <0.05). The PM morphometric characteristics of the South Indian Population, when compared with the baseline characteristics, showed a significant but variable degree of difference.

CONCLUSION: The findings of this study emphasize the importance of considering ventricular-specific PM morphometric data to optimize surgical strategies and prevent treatment failures.
Quantum Theory of Soul in Tao Science
Authors: Sha Zhigang , Xiu Rulin
Published: December 2024

The scientific study of the soul has garnered increased attention but remains limited in progress. We propose to give the soul a scientific definition and use quantum physics to predict its character, qualities, and behavior. In our previous work in Tao Science, we give quantum physics a new interpretation. We propose that quantum physics reveals that everything at the deepest level is a quantum vibrational field carrying information, energy, and matter. Observed quantum phenomena and conscious experiences occur when an observer absorbs these vibrations. We define the soul as the information within one’s quantum vibrational field. With this definition and quantum physics, we predict that: (1) The soul is the essence of existence, influencing energy and other system aspects. (2) The soul may persist beyond physical death. (3) The soul can be eternal despite physical limitations. (4) Souls can connect and communicate remotely. (5) The "Akashic Records" exist as a universal quantum field. (6) Spiritual abilities like intuition and telepathy can be scientifically explained. We discuss mathematical calculations, measurements, and experimental verification of these predictions. This quantum theory of soul supports monism, viewing the soul, spiritual heart, mind, energy, and matter as aspects of the quantum field, and endorses panpsychism, suggesting all things possess a soul. This work bridges science and spirituality, expanding scientific inquiry to include spiritual phenomena.
2.	Processes of differentiation in school education of independent Ukraine (historical and analytical aspect): monograph
Authors:   Institute of Pedagogy of the National Academy of Educational Sciences of Ukraine, Dichek N , Antonets N ,   Institute of Pedagogy of the National Academy of Educational Sciences of Ukraine, Gupan N ,   Institute of Pedagogy of the National Academy of Educational Sciences of Ukraine, Zagorodnyaya A ,   Institute of Pedagogy of the National Academy of Educational Sciences of Ukraine, Kulish T ,   Institute of Pedagogy of the National Academy of Educational Sciences of Ukraine, Shevchenko S ,   Institute of Pedagogy of the National Academy of Educational Sciences of Ukraine
Published: December 2024

The monograph reveals the processes of individualization in school education in Ukraine,
starting from the first years of independence, outlines the evolution of mechanisms
of humanization and optimization of school education (1991-2010). The educational policy
of the state in the field of introduction of personality-oriented education is covered. The contribution
of Ukrainian psychologists in the development of an individual approach to teaching
in primary and secondary education institutions is revealed; the formation and development of the psychological
service at school as a tool for implementing the processes of teaching and upbringing of children; shifts in the structure and activities of primary and secondary education institutions, in the education
of national minorities, in the textbook.
The materials of the monograph will be useful in lectures and methodological work in ZVO, in
institutes of air defense of Ukraine, in the research of scientists, graduate students, future teachers and teaching practitioners.
Exploring the Potentials of Integrating Immersive Virtual Reality (VR) Into Neuroanatomy Education
Authors: Siswanto Putri Alief , Pramanasari Indra , Dwijaksara Ni Luh Bella , Gusti Agrippina Waya Rahmaning
Published: December 2024

Neuroanatomy teaching requires students to understand complex spatial relations of the brain structures, traditionally accomplished using a cadaver. However, dissecting neuroanatomical structures remains a challenge due to their intricate nature. Digital technology is increasingly being adopted as a three-dimensional (3D) visualization tool, and immersive virtual reality (VR) has attracted great interest. A literature review was conducted using EMBASE, MEDLINE, Web of Science, Scopus, and ProQuest databases. Studies published from 2015 onwards that compared VR-based neuroanatomy teaching with traditional methods were included. Only English-language, peer-reviewed articles with quantitative learning outcomes were analyzed. This review included 6 studies and suggests that VR is non-inferior to other teaching methods and performs better in spatial-related questions. VR is also favored to increase student motivation and engagement. These positive learning experiences are expected to diminish neurophobia. Meanwhile, as a novel technology, challenges for incorporating VR into neuroanatomy education include costly technical requirements, inadequate image resolution, anatomy details, absence of texture perception, and health concerns such as cyber-sickness. Future studies should employ a large sample size (>100), assess participants' working memory and spatial abilities, conduct longer experiment duration, and examine long-term retention. Digital simulation through VR is also attainable and can be implemented further for neurosurgical training. As technology advances, immersive VR technology can potentially be an effective teaching tool for neuroanatomy.
Organization and Regulatory Base of Primary School Education in Israel: Specifics of Teaching Bedouin Students in Primary School
Authors: Abu-Frih Hanan
Published: December 2024

After the establishment of the state, there was a radical change in the life of the Bedouin Arabs in the Negev. They were not allowed to continue their traditional way of life in a short time. Bedouins are a destitute minority in a Western-oriented country. This change created the need for a formal education system that would deal with the new reality. Formal education became a prerequisite for the success of the Bedouin Arabs to adapt to the changes that have changed their lives due to the need for assimilation, partially or fully, in the Israeli economy for their livelihood. However, the formal education system is a fairly new framework in the Arab-Bedouin community in the Negev. Bedouin education frameworks were not formal, and the young men and women were educated through observation of adults and active participation in everyday life. The influence of the control system is so strong that teachers and education administration personnel are kept in the system of Arab education is afraid to even openly criticize the Ministry of Education. For example, in an article published in the Jerusalem Post on 14 December 2005, dealing with the sub-conditions at the school in one of the recognized Bedouin settlements in the Negev, the administrators and teachers agreed to speak only anonymously.
A Study on Elusive Enactment of BigData Analytics at University Level
Authors: Kumbhar Gajanan Shankar  , Prof (Dr) Virendra Kumar Sharma
Published: December 2024

In previous years big data applications are increasing everywhere which also forces education sector especially at university level to use big data for prediction of student performance and retention rate among college students at university. As technology changes at very fast speed big data analytics implementation in education will provide new ways of thinking. In this research paper tries to evaluate how big data analytics can be used for student’s performance evaluation and retention at university level. At university level students enrolling for various advanced studies are day by day increasing. Big data refers to large volume of data with technology and tools which are used to process and evaluate this large volume data which may be structured or unstructured format into insightful information for university. This paper tries to address the retention rate issue, history of big data, analytics methodologies for success at any university level students.
Integration of Blockchain-Based Decentralized Finance into Financial Planning and Analysis: A Framework for Corporate Finance Innovation
Authors: Prudhvi Uppaluri
Published: December 2024

The integration of Decentralized Finance (DeFi) into Financial Planning and Analysis (FPA) systems marks a pivotal transformation in corporate financial management, presenting organizations with unprecedented opportunities for operational efficiency, risk management, and strategic advancement. This article provides a comprehensive examination of the implementation framework, challenges, and strategic implications of incorporating DeFi technologies into traditional FPA systems. The article analyzes the technical architecture required for successful integration, including smart contract implementation, decentralized liquidity mechanisms, and blockchain-based audit systems, while addressing critical considerations in regulatory compliance and organizational change management. The article reveals significant potential for cost reduction, improved process efficiency, and enhanced risk management capabilities through DeFi integration while highlighting the importance of robust security protocols and governance frameworks. The article also identifies emerging opportunities in artificial intelligence integration, cross-chain interoperability, and industry-specific applications, offering valuable insights for organizations navigating this technological transformation. Furthermore, the article examines implementation challenges and provides strategic solutions for organizations undertaking DeFi integration initiatives. The article demonstrates that while the integration process presents complex technical and organizational challenges, the potential benefits in terms of operational efficiency, cost reduction, and competitive advantage make it a compelling strategic initiative for forward-thinking organizations. This article contributes to the growing body of knowledge on DeFi implementation in corporate settings and provides practical guidelines for organizations seeking to leverage blockchain technology in their financial operations.
Korelasi Nilai Laju Endap Darah dengan Gambaran Luas Lesi Radiologi Toraks Pada Pasien Tuberkulosis Paru Di Rumah Sakit Atma Jaya
Authors: Regina Pebriana  , Steffanus Mario , Budiman Yanto
Published: December 2024

Latar belakang: Tuberkulosis (TB) merupakan salah satu masalah kesehatan masyarakat yang penting di dunia, sepertiga penduduk dunia telah terinfeksi kuman TB. Dalam upaya menanggulangi penyakit TB, dibutuhkan diagnosis yang dapat ditegakkan melalui pemeriksaan bakteriologi, radiologi, dan pemeriksaan penunjang lain, seperti pemeriksaan nilai laju endap darah (LED). Infeksi TB berpengaruh terhadap peningkatan nilai LED dan pembentukan lesi radiologi pada TB Paru. Tujuan: untuk mengetahui korelasi nilai LED dengan gambaran luas lesi radiologi toraks pada pasien TB Paru di RS Atma Jaya Jakarta. Metode: Desain dalam penelitian ini adalah korelatif analitik dengan pendekatan cross-sectional. Sampel penelitian ini yaitu pasien TB paru dewasa baru aktif yang melakukan pengobatan di RS Atma Jaya sebanyak 68 pasien yang diambil dengan teknik consecutive sampling. Pengolahan data menggunakan metode korelasi Pearson dengan interval kepercayaan 95%, dilanjutkan dengan metode analisis regresi linear. Hasil: Penelitian menunjukan hubungan yang bermakna antara nilai laju endap darah (LED) dengan luas lesi radiologi toraks dengan koefisien korelasi 0,452  (p = 0,0001), artinya mempunyai kekuatan korelasi sedang. Hasil dari faktor perancu usia (p=0,906), jenis kelamin (p=0,887), dan gula darah sewaktu (p=0,056) tidak bermakna terhadap hubungan nilai LED dengan luas lesi radiologi toraks. Kesimpulan: Penelitian ini menunjukkan adanya hubungan bermakna antara nilai LED dengan luas lesi radiologi toraks pada pasien TB paru di RS Atma Jaya.
MANAGEMENT OF BUSINESS PROCESSES IN AN ORGANIZATION
Authors:   Zhytomyr Polytechnic State University, Tarasiuk Halyna , Pashchenko Olha ,   Zhytomyr Polytechnic State University, Zhyhadlo Larysa ,   Zhytomyr Polytechnic State University
Published: December 2024

The article considers theoretical and practical aspects of business process management, as well as methods for their improvement in the context of innovative development of enterprises. It is determined that business processes encompass a set of internal operations of an enterprise aimed at producing products or providing services that meet consumer requirements in terms of cost, quality, and level of service. The stages, classification, key characteristics and main problems that arise in the process of business process management are analyzed. It is determined that the business process management system should be aimed at increasing efficiency and effectiveness, for which it is necessary to create a clear system of activity analysis. Such a system should ensure not only the detection and elimination of shortcomings, but also the identification of the root causes of problems. An important emphasis is on determining the criteria for the effectiveness of business processes and their constant monitoring. It is established that reengineering and optimization remain the most popular approaches to improving business processes. It is important to understand that business processes are formed through interaction between divisions of the enterprise, ensuring the creation of final products or services that meet market needs. Process optimization allows not only to increase efficiency, but also to reduce costs, improve product quality and meet customer requirements. In this context, it is advisable for enterprises to use both gradual improvements through optimization and radical changes in the form of reengineering, depending on the goals and resources set. Key measures for improving business processes include in-depth analysis of existing operations, implementation of digital technologies, development of key performance indicator systems, training of personnel and ensuring compliance with international quality standards. Particular attention should be paid to aligning business processes with the overall company strategy, which will contribute to their harmonization and ensure the sustainability of operations. Effective business process management is an important factor in the development of an enterprise, allowing it to adapt to the challenges of the modern market, increase productivity, and ensure long-term stability of operations.
THE LATEST TRENDS OF THE NETWORK OF OIL PRODUCTS MARKETS IN THE WAR PERIOD TAKING INTO ACCOUNT THE INFLUENCE OF INTERNAL AND EXTERNAL FACTORS
Authors:   Odesa National Technological University, Antonyuk Oleg , Antonyuk Pavlo ,   State University "Institute of Market and Economic-Environmental Studies National Academy of Sciences of Ukraine"
Published: December 2024

The article analyzes the key aspects of functioning and ensuring the stability of critical systems in military and crisis situations. Such groups of factors as management and organizational structure, resource and financial security, human resources, technological and information systems, as well as a number of external threats are considered. Particular attention is paid to the impact of military actions, political risks, cyber threats and social and humanitarian crises on the effectiveness of management and the viability of organizations. The authors emphasize the importance of adaptive management models that are able to provide a quick response to challenges. An approach to the decentralization of management processes is proposed to increase their stability in conditions of unpredictable changes. It is emphasized that the availability of reserves of resources and financial instruments is a critical factor of stability. The authors emphasize the need to diversify funding sources, including international grants, loans and government support programs. It is noted that the training of qualified personnel is one of the key challenges in the conditions of military instability. It is recommended to implement training programs, in particular in the field of crisis management and cyber security. Technologies are identified as the basis of sustainability. Possibilities of implementing automated control systems, artificial intelligence technologies for threat monitoring and information protection, as well as the development of cyber protection as a priority direction are considered. The impact of global threats, including military and political risks, economic sanctions and blockades, which limit the ability to supply critical resources, is analyzed. The importance of international cooperation to neutralize these challenges is emphasized. Problems of social inequality, population resettlement, rising unemployment and other factors affecting the stability of the system are considered. The integration of humanitarian programs to support the population is proposed. Special attention is paid to terrorist acts, mobile attacks, physical and cyber threats. It is noted that modern aggression is often accompanied by hybrid methods that combine physical attacks with cyber activity. This requires a systematic approach to security. The article proposes comprehensive measures to increase resilience: development of risk management strategies, implementation of technologies for early detection of threats, development of crisis management and strengthening of cooperation with international partners.
THE ESSENCE OF LABOR RESOURCES OF THE ENTERPRISE
Authors:   Municipal enterprise "Kyiv Metropolitan", Mazur Dmytro , Mazur Oleksandr ,   Kyiv University of Market Relations, Mazur Halyna ,   Higher educational institution "International University of Business and Law", Bezdolnyi Serhii ,   Higher educational institution "International University of Business and Law"
Published: December 2024

The authors of the article have revealed the issue of labor resources and their economic essence. The characteristic features of the company's labor resources are determined. Human resources, which are the driving force of society, were considered to accurately reveal the essence of labor resources. The concept of "labor resources" is recognized. Several approaches to understanding the essence of the company's labor resources are highlighted. In this article, the authors define that labor resources are the able-bodied part of the population that has physical and mental needs, is capable of producing material goods or providing services. This study outlines the aspects of the enterprise's competitiveness, which provides an opportunity to increase labor resources and directions of development. The article determined that the sufficient guarantee of the enterprises with the necessary labor resources, their appropriate use, a high level of labor efficiency are of great importance for the development of production volumes and the development of production efficiency. Labor potential is the possibility of using the company's labor resources for the future. This includes the capabilities and skills of employees that may not be used in the firm today, but may be brought in for the cause in the future. Labor potential, valid and possible, is the only one of the most important objects of management at the same level of macro systems (country, territory, sphere), as well as micro systems (company). Moments of continuous workers who have received the necessary special training or practical knowledge of work are used to survey the entire set of company workers. Instead of full-time employees, the company's operation will be able to be co-opted by other working individuals on the basis of a non-permanent collective agreement. In this study, the authors of the article show that the labor potential is a system that has an extended and temporal orientation, the elements of which are labor resources, taking into account the entire complex of their numerous and qualitative characteristics, employment and workplaces. The concept of labor resources and their essential characteristics are defined.
Mucho cuidado si ves aparecer la «aleta de tiburón»
Authors: Blanco-López Emilio , Sánchez-Pérez Ignacio , Freites-Esteves Alfonso , D'Ascoli Giulio , Esteban-Lucía Laura
Published: December 2024

El electrocardiograma (ECG) continúa siendo la herramienta diagnóstica fundamental para guiar el manejoterapéutico de pacientes con sospecha de síndrome coronario agudo (SCA). Además del ascenso del segmentoST, existen patrones electrocardiográficos que, por implicar alto riesgo, requieren el planteamientode una estrategia de revascularización precoz. Describimos el caso de un paciente que consultó por clínicaanginosa, objetivándose en el ECG el denominado patrón de «aleta de tiburón».
«Cristales verdes de la muerte»: un hallazgo poco común en la puerta de Urgencias
Authors: Fernández-Martín Paloma , Torrado-Carrión Ramiro Antonio , García-Corbalán Marta
Published: December 2024

La presencia de inclusiones verde azuladas en neutrófilos, conocidas como «cristales verdes de la muerte»,es un hallazgo infrecuente en sangre periférica. Su origen es desconocido, asocian fallo hepático agudoen pacientes críticamente enfermos y presentan altas tasas de mortalidad, variando del 30-100%, en lassiguientes 24-72 horas. Su presencia ha de considerarse como un marcador de mal pronóstico, siendo comunicadopor el especialista de Laboratorio clínico al equipo médico para prevenir el fracaso multiorgánico.Se describe aquí un caso de inclusiones citoplasmáticas verde azuladas en una paciente con shock sépticoy fallo hepático agudo secundario a infección por neumococo.
Hepatopatía crónica inmune-like por imatinib
Authors: Blázquez-Ávila Víctor , Rodríguez-Martín Laura , Álvarez-Cañas María Concepción , De las Heras-Rodríguez Natalia
Published: December 2024

Diversos fármacos pueden generar distintos tipos de daño hepático. Aquellos relacionados con el controlinmune pueden desencadenar un daño hepático agudo de tipo autoinmune, semejante a una hepatitisaguda autoinmune o reactivación de hepatitis B crónica inactiva. Los inhibidores del receptor de tirosinaquinasa (ITK) tienen un amplio uso para el tratamiento de ciertas enfermedades a través del control inmune.Describimos el caso de un paciente en tratamiento con imatinib, un tipo de ITK, para una neoplasia mieloproliferativacrónica con un daño hepático atípico en forma de fibrosis rápidamente progresiva.
Hepatitis autoinmune inducida por drogas: asociación con nitrofurantoína
Authors: Manchamé-Moreno Raúl Fabrizio , Borrayo-Alvarado Christyan Arturo
Published: December 2024

Mujer de 24 años de edad con historia de infección del tracto urinario (ITU) 3 semanas antes, tratada connitrofurantoína. Comenzó con ictericia, malestar general y dolor abdominal, por lo que consultó a Urgencias,donde se evidenció elevación de transaminasas, y en estudios posteriores presentó positividad para anticuerposantinucleares (ANA) y anticuerpos antimúsculo liso (ASMA). Se realizó biopsia hepática que mostróinfiltrado de linfocitos y hepatitis de interfase, con lo que se llegó al diagnóstico de hepatitis autoinmuneinducida por drogas, secundaria a nitrofurantoina, además, se inició tratamiento con corticosteroides conadecuada evolución.
Tatar ve Başkurt Söz Yapımında Yeni Bir Birleşik Ek: +lıklı / +lěklě
Authors: ÖZŞAHİN Murat
Published: December 2024

Söz yapımının fonetik, morfolojik, söz birleştirme, söz gruplarının birleşik söze evrilmesi, ek yardımı ile birleşik sözlerin oluşumu, tür ve işlev değişikliği, kısaltmalar gibi çok çeşitli yolları vardır. Türk dilinin yapısı gereği bunların en aktif olanı ise şüphesiz morfolojik yoldur. Ekler, frekanslarına göre her dönemde üretken, az üretken veya ölü olarak sınıflandırılırlar ve gramerlerimizde ya alfabetik ya da frekansları bakımından sıralanırlar. Frekansları dışında yapı bakımından da eklerin çeşitli tasnifleri vardır. Bunlar, en temelde basit ve birleşik ekler olarak tanımlanırlar. Birleşmelerinin ne zaman gerçekleştiği tam olarak belirlenemeyen birleşik eklerin genel olarak yazı dili tarihinin ilk ve orta dönemlerinde oluştuğu ifade edilir. Ancak bu durum, dilin sürekliliği bağlamında içinde bulunduğumuz zamanın dilin var oluş süreci olarak kabul edilmediğinin de bir göstergesidir. Hâlbuki ek birleşmeleri, bu devamlılık içerisinde yakın dönemde de meydana gelebilir. Bu makale, bir ek birleşmesinin birkaç yönden karşılaştırmalı olarak nasıl tespit edilebileceğine dair yöntem ortaya koymayı hedeflemektedir. Tatar ve Başkurt edebî dillerinde tespit edilen ve insana dair nitelikleri ifade etme görevinde kullanılan +lIklI (+lIk+lI) ekinin varlığına işaret edilmektedir. +lIk ekinin başka eklerle birleşerek yeni biçimler meydana getirdiğini gösteren örnekler farklı çalışmalarla da ortaya koyulmuştur. Çalışma sırasında tercih edilecek terimde ortaya çıkabilecek belirsizliğin önüne geçmek amacıyla birleşik ek, ek kalıplaşması, ek yığılması terimlerinin kapsamı üzerine düşüncelere yer verilmiştir. Bu düşünceler ışığında +lIklI eki, birleşik bir ek olarak tanımlanmıştır.
Oğuz Grubu Yazı Dilleri ve Ağızlarında Yeterlik Kategorisi
Authors: DOĞAN Talip
Published: December 2024

Yeterlik, bir eylemin mümkün veya muhtemel olup olmadığının bildirildiği kategoridir. Tarihî ve çağdaş Türk dili alanında yeterlik kategorisinin işaretleyicileri, lehçeleşme seyri ve dil ilişkileri gibi birtakım faktörlere bağlı olarak çeşitlenmiştir. Çağdaş Oğuz alanlarında olumlu ve olumsuz yeterlik için temelde üç tip dizilişten bahsedilebilir: -A bil- ve -AmA- (< -A uma-); -A bil- ve -A bilme- ~ -AmmA- (~ vd.); -p ~ -A bil- ve -p ~ -A bilme-. -A bil- ve -AmA- (< -A uma-) dizilişleri, Türkiye Türkçesinin yazı dili ile Batı ve Kuzeydoğu grubu ağızlarında, Kıbrıs Türk ağızlarında; Balkan (Rumeli) Türk ağızlarında; Suriye Türk ağızlarında; Gagavuz Türkçesinin yazı dili ile ağızlarında kullanılmaktadır. -A bil- ve -A bilme- ~ -AmmA- (~ vd.) dizilişleri, Azerbaycan Türkçesi yazı dili ve ağızlarında; Irak Türk ağızlarında; Türkiye’deki Doğu Grubu ağızlarında; Sungur Türkçesinde; Kaşkay Türkçesinde ve Horasan Türkçesinde yerleşmiştir. -p ~ -A bil- ve -p ~ -A bilme- dizilişleri ise Türkmen Türkçesi ve Harezm Oğuz alanlarında hâkimdir. Diğer taraftan resmî ve baskın dillerle bir arada kullanılan Oğuz alanlarında kopyalanmış sistemler de yaygınlaşmıştır. Örnek olarak İran sahasında Güney Azerbaycan, Sungur, Kaşkay ve Horasan ağızlarında Farsçadaki yeterlik sisteminden kopyalanmış olan başar- ~ başarma- + kip eki + esas fiil + istek ~ emir eki dizilişi yer almaktadır.