bluuebunny/crossref_metadata_2025 huggingface dataset:
Detection and quantification of perioperative heparin-like effects by rotational thromboelastometry in living-donor liver transplant recipients: A prospective observational study
Authors: Yassen Khaled A. , Refaat Emad K. , Helal Safaa M. , Metwally Ahmed A. , Youssef Sherin D. , Görlinger Klaus
Published: May 2023

Background and Aims:

Heparin-like effects (HLEs) can affect hemostasis during liver transplantation. The aim of this study was to assess the perioperative incidence and severity of HLE with rotational thromboelastometry (ROTEM) and activated partial thromboplastin time (aPTT).

Material and Methods:

ROTEM and aPTT were measured intraoperatively and on postoperative days (POD) 1, 3, and 7. HLE was identified if ROTEM INTEM/HEPTEM CT-ratio was >1.25 and severe forms of HLE when ratio was ≥2. Based on aPTT, HLE was defined when aPTT ratio was >1.25 (patient aPTT/control aPTT).

Results:

Thirty-eight recipients were included. Variable degrees of HLE were detected by aPTT-ratio and INTEM/HEPTEM CT ratio. No significant correlation existed between both ratios. Based on INTEM/HEPTEM CT ratio, HLE was detected in 7/38 during anhepatic phase, 19/38 post-reperfusion, 10/38 on POD1, 4/38 on POD3, and 0/38 on POD7. Four cases of severe HLE were identified by INTEM/HEPTEM CT ratio only in the anhepatic phase. Postoperative infusion of unfractionated heparin led to mild-moderate HLE on POD1 and 3 as evident by both tests. Red blood cell and plasma transfusion were higher with severe HLE (1350 ± 191 ml and 3558 ± 1407 ml). Composite adverse outcome of any complication or death within 3 months for patients without HLE, mild-moderate HLE, and severe HLE as detected by ROTEM was 27.8%, 42.9%, and 66.7%, respectively.

Conclusion:

INTEM/HEPTEM CT ratio was able to detect and quantify HLE as aPTT ratio. The ability of the INTEM/HEPTEM CT ratio to identify severe HLE earlier in the anhepatic phase needs to be studied in a larger population. HLE is self-limiting, but when identified in a severe form, it is associated with worse outcome.
Comparison of the effects of caffeine, aminophylline, and saline on the recovery from total intravenous anesthesia in laparoscopic surgeries: A randomized controlled trial
Authors: Hari Prasad R. , Paliwal Bharat , Kamal Manoj , Bhatia Pradeep Kumar
Published: May 2023

Background and Aims:

The return of consciousness (ROC) after general anesthesia (GA) is by stopping the administration of anesthetic agents. At present, no drug is given to reverse the loss of consciousness produced by general anesthetic agents. This study is conducted to find whether caffeine and aminophylline hasten the ROC.

Material and Methods:

This study was conducted on 75 American Society of Anesthesiologists (ASA) I and II female patients undergoing laparoscopic hysterectomy, aged between 18 and 60 years. The patients were divided into three equal groups (Group C: caffeine citrate, Group A: aminophylline, and Group S: saline) of 25 each by a computer-generated random number table. GA was induced with propofol, fentanyl, and maintained with propofol infusion. On completion of the surgery, the neuromuscular blocking agent was reversed and then the infusion of propofol was stopped. The study drug was administered intravenously when the BIS 60 was achieved. Time to achieve BIS 90, return of first gag reflex, eye-opening on verbal command, and extubation after study drug administration were noted. Hemodynamic parameters and SpO2 were also monitored.

Results:

The time for BIS 60 to 90 was 10 (4.25) min in the caffeine group, 13 (4.25) min in the aminophylline group, and 26 (9.0) min in the saline group. The time to return of gag reflex and time to extubation were shorter in the caffeine and aminophylline group compared to the saline group. The time to eye-opening on verbal command was shorter in the aminophylline group compared to the saline group. Hemodynamic parameters after infusion of the study drug were comparable in all three groups.

Conclusion:

Caffeine hastens the recovery from total intravenous anesthesia with propofol and fentanyl in laparoscopic hysterectomy as effectively as aminophylline.
Suppression of perioperative stress response in elective abdominal surgery: A randomized comparison between dexmedetomidine and epidural block
Authors: Salhotra Rashmi , Kamal Vishal , Tyagi Asha , Mehndiratta Mohit , Rautela Rajesh S. , Almeida Edelbert A.
Published: May 2023

Background and Aims:

Stress response after surgery induces local and systemic inflammation which may be detrimental if it goes unchecked. Blockade of afferent neurons or inhibition of hypothalamic function may mitigate the stress response.

Material and Methods:

A total of 50 consenting adult ASA I/II patients undergoing elective abdominal surgery were randomized to receive either dexmedetomidine (Group D) or epidural bupivacaine (Group E) in addition to balanced general anesthesia. Laparoscopic surgery, contraindications to epidural administration, history of psychiatric disorders, obesity (BMI >30 kg/m2), on beta blockers or continuous steroid therapy for >5 days over last 1 year, and known case of endocrine abnormalities or malignancy were excluded. Serum cortisol, blood glucose, and blood urea were estimated. Hemodynamic parameters, total dose of dexmedetomidine, bupivacaine, emergence characteristics, and analgesic consumption over 24 h postoperatively were recorded. Statistical comparisons were done using Student’s t-test, repeated measure analysis of variance followed by Dunnett’s test, generalized linear model and Chi-square/Fisher’s exact test. A P value <0.05 was considered significant.

Results:

Serum cortisol levels were significantly lower in group E than group D 24 h after surgery (P = 0.029). Intraoperative and postoperative glucose level was lower in group E compared with group D. Time to request of first rescue analgesic was longer in group E than group D (P = 0.040). There was no significant difference between the number of doses of paracetamol required in the postoperative period (P = 0.198).

Conclusion:

Epidural bupivacaine was more effective than intravenous dexmedetomidine for suppression of neuroendocrine and metabolic response to surgery. Dexmedetomidine provided better hemodynamic stability at the time of noxious stimuli and postoperatively.
Evaluating the Effect of Gargling with Hydrogen Peroxide and Povidone-Iodine on Salivary Viral Load of SARS-CoV-2: A Pilot Randomized Clinical Trial
Authors: Adl A , Sedigh-Shams M , Jamalidoust M , Rajabzadeh Z
Published: May 2023

ABSTRACT

Background and Aim:

This study evaluates the salivary viral load of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in hospitalized patients and outpatients before and after gargling with 1% hydrogen peroxide and 0.25% povidone-iodine in comparison with normal saline.

Patients and Methods:

This clinical trial was conducted on 120 participants with laboratory-confirmed coronavirus disease 2019 (COVID-19) in two groups: outpatients (n = 60) and hospitalized patients (n = 60). In each group, the patients were randomly divided into three subgroups of 20 based on their given mouthwash for gargling (hydrogen peroxide, povidone-iodine, or normal saline). Two saliva samples were taken from each patient: the first one before gargling and the second one 10 minutes after gargling 10 ml of the respected mouthwashes for 30 seconds. The TaqMan real-time polymerase chain reaction (PCR) amplification of SARS-CoV-2 was used to measure the viral load.

Results:

Saliva samples from 46% of patients were positive for coronavirus before gargling the mouthwashes. The percentage of patients with an initial positive saliva sample was significantly higher in the outpatient group (83.3%) than in the hospitalized group (5.4%) (P = 0.01). According to the findings, gargling any mouthwash similar to saline did not reduce the viral load (P > 0.05).

Conclusion:

The saliva of COVID-19 patients in the initial stage of the disease was more likely to contain SARS-CoV-2 than the saliva of the hospitalized patients. Gargling hydrogen peroxide or povidone-iodine did not reduce the salivary SARS-CoV-2 viral load.
Can Montelukast Sodium be an Alternative Treatment in the Treatment of Interstitial Cystitis?
Authors: Günizi ÖC , Kol A , Günizi H
Published: May 2023

ABSTRACT

Background:

The leukotriene D4 receptors have been detected in human bladder detrusor myocytes, and they can play the role of interstitial cystitis etiology.

Aim:

Our study aims to explain the role of mast cells histologically and immunohistochemically in the pathogenesis and the effectiveness of montelukast that leukotriene D4 receptor antagonist in the treatment of interstitial cystitis.

Subjects and Methods:

Twenty-four Wistar albino adult female rats were used. Group 1 (n = 8): control (sham) group, Group 2 (n = 8): interstitial cystitis group, and Group 3 (n = 8): treatment group. Groups 2 and 3 rats were administered 75 mg/kg cyclophosphamide four times every three days intraperitoneally. The rats in the treatment group were started on montelukast sodium as 10 mg/kg, 1 × 1/day per orally after the last administration of cyclophosphamide and were given for 14 days. Mast cells in the bladder tissues were examined histologically, and the presence of IL-6, 8, VEGF, and TNF alpha was examined immunohistochemically.

Results:

Thin transitional epithelium, loose connective tissue, weak smooth muscle bundles, and signs of chronic inflammation were observed in the interstitial cystitis group. Regenerated transitional epithelium, intact basement membrane, compact lamina propia, thick smooth muscle bundles, and rare inflammatory cells were observed after the treatment with the montelukast. Mast cells were decreased in bladder tissue after treatment. IL-6, IL-8, VEGF, and TNF alpha levels were significantly decreased after treatment.

Conclusions:

We found that inflammatory mediators were significantly reduced after treatment with montelukast in the interstitial cystitis group. Montelukast can be used as an effective drug in the treatment of interstitial cystitis.
Evaluation of the Clinical Impact and In Vitro Antibacterial Activities of Two Bioactive Restoratives against S. mutans ATCC 25175 in Class II Carious Restorations
Authors: Maher YA , Rajeh MT , Hamooda FA , Zerain GO , Habis RM , Sulaimani RH , Albar ST , Ali FMH , Abdelaleem NA
Published: May 2023

ABSTRACT

Background:

Streptococcus mutans is a Gram-positive opportunistic bacterial pathogen and that causes dental caries and then restorative treatment remains the best clinical practice approach to repair and prevent dental caries.

Aims:

This study compared the antimicrobial performance of resin modified glass ionomer cement (RM-GIC) and ACTIVA restoratives by evaluating the S. mutans count, pH levels, and plaque index (PI) scores before and on the 7th day of restoration, and then determined the antimicrobial activities against S. mutans ATCC 25175 in both restoratives in vitro.

Materials and Methods:

Seventy-eight eligible Saudi female participants, with class II carious lesions, were randomly distributed into RM-GIC and ACTIVA restorative groups. We evaluated the S. mutans count by the serial dilution technique and salivary pH by using a portable pH meter. The PI scores were determined by Silness–Löe method and the antibacterial activity by the agar well diffusion method. Statistical analysis of normality distribution was performed with the Kolmogorov-Smirnov and the difference between groups was an analysis by paired t-test. In addition, the independent sample was compared with the independent samples t-test.

Results:

Both groups reduced the S. mutans count, pH acidity, and PI scores, and this reduction was statistically significant on the 7th day of restoration (P < 0.05), preference for ACTIVA. The in vitro antibacterial activity against S. mutans ATCC 25175 showed a non-significant difference between both bioactive restorative materials (P < 0.05).

Conclusion:

The novel application of ACTIVA restorative material is a promising option for patients at risk of caries.
Clinical Predictors of Covid-19 Mortality in a Tertiary Hospital in Lagos, Nigeria: A Retrospective Cohort Study
Authors: Akase IE , Akintan PE , Otrofanowei E , Olopade OB , Olorunfemi G , Opawoye A , Ima-Edomwomyi UE , Akinbolagbe YO , Agabi OP , Nmadu DA , Akinbode GO , Olasope AC , Ogundare A , Bolarinwa AB , Otokiti EO , Enajeroh PJ , Karami M , Esezobor CI , Oshodi Y , Oluwole AA , Adeyemo WL , Bode CO
Published: May 2023

ABSTRACT

Background:

The predictors of mortality among patients presenting with severe to critical disease in Nigeria are presently unknown.

Aim:

The aim of this study was to identify the predictors of mortality among patients with COVID-19 presenting for admission in a tertiary referral hospital in Lagos, Nigeria.

Patients and Methods:

The study was a retrospective study. Patients’ sociodemographics, clinical characteristics, comorbidities, complications, treatment outcomes, and hospital duration were documented. Pearson’s Chi-square, Fischer’s Exact test, or Student’s t-test were used to assess the relationship between the variables and mortality. To compare the survival experience across medical comorbidities, Kaplan Meir plots and life tables were used. Univariable and multivariable Cox-proportional hazard analyses were conducted.

Results:

A total of 734 patients were recruited. Participants’ age ranged from five months to 92 years, with a mean ± SD of 47.4 ± 17.2 years, and a male preponderance (58.5% vs. 41.5%). The mortality rate was 9.07 per thousand person-days. About 73.9% (n = 51/69) of the deceased had one or more co-morbidities, compared to 41.6% (252/606) of those discharged. Patients who were older than 50 years, with diabetes mellitus, hypertension, chronic renal illness, and cancer had a statistically significant relationship with mortality.

Conclusion:

These findings call for a more comprehensive approach to the control of non-communicable diseases, the allocation of sufficient resources for ICU care during outbreaks, an improvement in the quality of health care available to Nigerians, and further research into the relationship between obesity and COVID-19 in Nigerians.
Effects of Misoprostol in Reducing Blood Loss during Abdominal Myomectomy in Nigeria
Authors: Nnagbo JE , Dim CC , Eze MI , Mba SG
Published: May 2023

ABSTRACT

Background:

Despite using a tourniquet to reduce bleeding during abdominal myomectomy, the procedure is still complicated by significant intraoperative bleeding.

Aim:

To determine whether misoprostol and tourniquet compared with tourniquet alone would significantly reduce bleeding during abdominal myomectomy at two tertiary hospitals in Enugu.

Materials and Methods:

This study is an open-label randomized controlled trial. A total of 126 consenting participants were recruited from women booked for abdominal myomectomy at the study centers over 7 months. They were randomized into groups A (vaginal misoprostol 400 μg) and B (no misoprostol) one hour before surgery. Intraoperatively, all participants had a tourniquet application. Intraoperative and postoperative blood loss was compared between the two groups. Descriptive and inferential analyses were carried out using IBM SPSS Version 22.0. A P- value of < 0.05 was considered statistically significant.

Results:

An intention-to-treat analysis was carried out. All 63 participants (100%) and 56 (90%) completed the study according to the protocol in groups A and B, respectively. Socio-demographic characteristics were not significantly different in both groups. The mean intraoperative blood loss in the “misoprostol group” (522.6 ± 127.91 ml) was significantly lower than in the “no-misoprostol group” (583.5 ± 186.20 ml), with P = 0.028. The difference in mean hemoglobin (g/dl) was lower in the “misoprostol group” than in the “no-misoprostol group” (1.3 ± 0.79 vs. 1.9 ± 0.89, P < 0.001). The mean 48 hours postoperative blood loss (ml) between the two groups was 323.8 ± 221.44 vs. 549.4 ± 519.72), with P = 0.001.

Conclusion:

Among women receiving tourniquet during myomectomy in Enugu, the additional use of vaginal misoprostol 400 μg significantly reduced intraoperative blood loss.
Androgenetic Alopecia: Traditional Cardiovascular Risk Factors, Metabolic Syndrome, and Component Traits among Nigerian Adults
Authors: Oiwoh SO , Akinboro AO , Olayemi O , Salawu AA , Olasode OA , Onayemi EO
Published: May 2023

ABSTRACT

Background:

Androgenetic alopecia (AGA) has been linked to cardiovascular diseases (CVDs) and metabolic syndrome (MetS). Works on AGA, cardiovascular risk factors (CVRFs) and MetS are rare among Nigerians.

Aim:

This study set out to determine the relationship among CVRFs, MetS, and AGA.

Subjects and Methods:

This is a cross-sectional study done among adults who were 18 years and above in selected communities in Ogbomoso on 260 consenting AGA participants as well as 260 age controls without AGA. They were matched for age and sex using a multistage sampling method. Anthropometric measurements, fasting blood glucose, and lipid profile samples were collected. MetS was diagnosed using International Diabetes Federation criteria. Data were analyzed using IBM SPSS version 20. Ethical approval was gotten before commencement of the study (LTH/OGB/EC/2017/162).

Result:

Metabolic syndrome in AGA was higher than in controls (8.08% vs. 7.69%, p = 0.742). AGA was significantly associated with elevated mean systolic blood pressure (SBP) (p = 0.008), low High Density Lipoprotein (HDL-c) (p < 0.001), alcohol intake (p < 0.001), dyslipidaemia (p = 0.002), and sedentary lifestyle (p = 0.010). The correlates of AGA severity in male and female gender are age (p < 0.001 and 0.009 respectively), SBP (p = 0.024) and abdominal obesity (p = 0.027) in male gender.

Conclusion:

AGA in Nigerians is associated with dyslipidaemia, alcohol intake, and sedentary lifestyle. AGA severity is related to age, higher mean SBP, abdominal obesity and low HDL-c in male and age, and Body mass index in females. Nigerians with AGA should be screened for dyslipidaemia and counseled against the use of alcohol and sedentary lifestyle.
Evaluation of the Performance of Simple Laboratory Parameters used in the Diagnosis of Acute Appendicitis
Authors: Karatas T , Selcuk EB , Karatas M , Yildirim A , Bitirim MA , Orman I
Published: May 2023

ABSTRACT

Background:

Acute appendicitis (AA) is one of the most common emergency surgery.

Aim:

To evaluate the performance of laboratory parameters used in the diagnosis of AA.

Subjects and Methods:

There were two groups. In both groups, leukocyte (WBC), neutrophil, lymphocyte count, neutrophil/lymphocyte ratio (NLR), mean platelet volume (MPV), red cell distribution width (RDW), and platelet distribution width (PDW) values were examined in complete blood count (CBC). In addition, serum bilirubin (total bilirubin and direct bilirubin) values were examined. All laboratory parameters studied were compared to evaluate their diagnostic performance.

Results:

A total of 128 people were in the AA group and 122 people were in the healthy group (control). WBC count, neutrophil count, NLR, total bilirubin, direct bilirubin, and PDW values were significantly higher in the AA group than in the control group (P value <0.05). Lymphocyte counts and MPV values in the AA group were significantly lower than in the control group (P value <0.05). The sensitivity and selectivity of the WBC and neutrophil counts in AA were 95.13%, 89.34%, 94.53%, and 93.44%, respectively. The sensitivity and selectivity of the total bilirubin values were 59.38% and 73.77%, respectively. Area under the ROC curve (AUC) values within 95% confidence interval were over 0.900 for neutrophil count, WBC count, direct bilirubin, NLR, and PDW values. AUC values for total bilirubin, lymphocyte count, RDW, and MPV values were below 0.700.

Conclusions:

Diagnostic performances of the laboratory parameters were determined as follows: neutrophil count > WBC count > direct bilirubin = NLR = PDW > total bilirubin = lymphocyte count = RDW = MPV.
Effect of Glove use on Manual Dexterity of Nursing Students
Authors: Denat Y , Kuzgun H
Published: May 2023

ABSTRACT

Background:

Manual dexterity is vital in nursing. Nurses need to carry out applications requiring manual dexterity in the quickest and most accurate way. However, gloves are also necessary during such applications as a precaution against infections. Therefore, manual dexterity and the effect of gloves on manual dexterity are essential subjects to be investigated in the nursing field.

Aims:

This study aims to determine the effect of using gloves on the manual dexterity of nursing students.

Materials and Method:

The sample of the semi-experimental study consisted of 80 nursing students. The data were collected using a questionnaire and Purdue Pegboard Test.

Results:

The participants were 22.03 ± 1.35 years of age on average; 61.2% of them were 22 years of age or above, 50% were female, 50% were male, 50% were in the third grade, 50% were in the fourth, 80% were high school graduates, and 97.5% did not work in any job. As a result, 47.5% reported that gloves impacted their manual dexterity, 52.5% reported only a partial effect, 12.5% indicated that gloves increased their manual dexterity, 66.3% stated that it reduced their manual dexterity, and 21.2% reported no change. The right-hand and assembly scores were found to be significantly higher in the tests performed with bare hands than in the tests performed with gloves (P < 0.05).

Conclusions:

Using latex gloves impacts the dominant-hand dexterity and assembly dexterity. Therefore, designing more ergonomic gloves, increasing nurses’ habit of working with gloves already in school, and supporting the improvement of their manual dexterity with gloves are recommended.
Evaluación del Sargazo (Sargassum spp.) como componente de sustratos agrícolas
Authors: Herrera-Monroy S. , Ordaz-Chaparro V. M. , Valdés-Velarde E.
Published: May 2023

El sargazo (Sargassum spp.) es una macroalga parda que durante la última década ha presentado arribos anómalos en playas caribeñas, generando una problemática al turismo local por el aspecto y olor que adquiere cundo se descompone sobre el litoral. Para dar alternativas de manejo algunas investigaciones han propuesto incorporarlo a diferentes procesos industriales que van desde la cosmética, la construcción y la producción de alimentos. Dentro este último, se han reportado tratamientos para su acondicionamiento físico-químico y posterior uso como sustrato agrícola, sin embargo, las investigaciones de su desempeño son escasas. Por ello en el presente trabajo se determinaron las características físicas y químicas de una muestra del alga colectada en Puerto Progreso, Yucatán, México, así como las implicaciones de estas sobre la germinación de dos especies hortícolas. Las determinaciones fueron comparadas con las características y desempeño de turba (Sphagnum spp. Comercialmente llamado Peat moss®). Los resultados mostraron propiedades físicas desfavorables cuando se usa como componente único, así como una alta concentración de plomo (Pb), ion sodio y calcio que limitan su uso en la industria alimenticia, además de que interfieren negativamente con las etapas de germinación. Debido a esto, se recomienda probar mezclas de sargazo con otros materiales que permitan mejorar sus características físicas, así como amortiguar las concentraciones de metales, además de idear mecanismos para reducir su concentración o eliminarlos completamente del sustrato.
Pursuing a gender and women empowerment agenda: A chronicle of Women Ministry in the Blantyre Synod of the Church of Central Africa Presbyterian (CCAP) in
Malawi from 1876 to 2023
Authors: Zgambo Rev. Dr. Humphreys Frackson
Published: May 2023

In this world, women face a plethora of problems such as discrimination, violence, abuse and varied unequal treatment at home, at school, at the work place, at religious institutions and in wider society (Muriithi, 2000:12-13). Women discrimination in the church has been an area of great concern and reflection for many decades. The major challenges have inter alia been about the status, authority of women, ordination and inclusion of women in the decisionmaking bodies of the church. Such Issues including full participation and inclusion of women in church structures have been partially explored, but not convincingly exhausted (Muriithi, 2000:12-13). Such questions of a gender and women empowerment agenda in the Blantyre Synod have been pursued through the approach of engagement with women in all spheres of life. The study investigates, scrutinizes and analyses how the Blantyre Synod of the Church of Central Africa Presbyterian (CCAP) has managed to engage women on a gender and ministry agenda from as early as 1876 CE to the present day in Malawi.
Curve counting and S-duality
Authors: Feyzbakhsh Soheyla , Thomas Richard P.
Published: May 2023

We work on a projective threefold $X$ which satisfies the Bogomolov-Gieseker conjecture of Bayer-Macr\`i-Toda, such as $\mathbb P^3$ or the quintic threefold. We prove certain moduli spaces of 2-dimensional torsion sheaves on $X$ are smooth bundles over Hilbert schemes of ideal sheaves of curves and points in $X$. When $X$ is Calabi-Yau this gives a simple wall crossing formula expressing curve counts (and so ultimately Gromov-Witten invariants) in terms of counts of D4-D2-D0 branes. These latter invariants are predicted to have modular properties which we discuss from the point of view of S-duality and Noether-Lefschetz theory.

Comment: Referee's corrections implemented; journal version. 25 pages, 4 figures
Transformational Leadership and Knowledge Management Impact on Organization Performance: A Systematic Review
Authors: Hadi Tan , Marpaung Alexander Batara
Published: May 2023

A leader is a frontrunner who will bring an organization to sail to its desires. In wearing out its functions a leader will normally use the management style/version this is believed to be the most perfect to support his achievement. Transformational leadership is leadership that gives freedom to the enterprise to offer thoughts for the progress of the employer, lets in subordinates to see troubles from special views, enables adapt to the converting environment, and improves the effectiveness of Human aid control in numerous sectors of the business enterprise. The influence of transformational management on organizational overall performance through expertise control has been studied in various research. This journal is the end result of systematic opinions from several journals on the influence of transformational management and information control on organizational overall performance. From the consequences of the literature search, five journals related to transformational leadership and know-how management effect on organizational overall performance had been determined. The consequences of the systematic evaluation show that the transformational management fashion and information management has a positive influence on enterprise performance, both at once and in a roundabout way.
Brand Equity, Offering Equity, and Relationship Equity (BOR) Influence toward Customer Loyalty of Lombok Paradise Pearl Product
Authors: Trijayati Dini , Heikal Jerry
Published: May 2023

The research was conducted with the aim of proving the influence of Brand Equity, Offering Equity, and Relationship Equity on Customer Loyalty for Mutiara Lombok Paradise Products, with a sample of 104 samples. The method in this paper is non-probability sampling and the samples are randomly selected by means of stratified random sampling. The primary data used in this research is primary funds. This study has a hypothesis, namely Brand Equity, Offering Equity, and Relationship Equity on Customer Loyalty for Mutiara Lombok Paradise Products. Data was collected with the help of a questionnaire with a differential semantic scale for the dependent variable and a binary scale for the independent variable. The research results were analyzed using the SPSS (Statisical Program for Social Science) method. The study found that (1) Brand Equity has a significant effect on customer loyalty (2) Offering Equity has a significant effect on customer loyalty (3) Relationship equity has a significant effect on customer loyalty (4) Brand equity, Offering Equity, and Relationship equity both have an effect significant effect on customer loyalty.
Description of Clean and Healthy Behavior Program Implementation at School During COVID-19 Pandemic at Depok City Health Office in 2021
Authors: Ardiani Hadiah
Published: May 2023

COVID-19 pandemic has had an impact on social activities, one of which is teaching and learning activities in schools. This research aims to discuss an overview of the implementation carried out by the Depok City Health Office in order to increase the coverage of School PHBS during the COVID-19 pandemic in 2021.This preliminary study is a qualitative research with a descriptive approach.The data collection process was carried out using in-depth interviews and document review methods. This research shows that the implementation of the PHBS program in school settings is carried out through health human resources who adapt to teamwork mechanisms, available facilities and infrastructure, budgets and technical instructions that go through an adaptation process during the COVID-19 pandemic as well as the dynamics of school activities based on existing regulations. applies in Depok City related to learning activities in schools. The obstacles experienced include limited facilities in schools and the process of implementing online monitoring and coaching activities has resulted in a gap in response in several schools implementing the PHBS program.The implementation of the PHBS program for schools during the COVID-19 pandemic at the Depok City Health Office, which was reviewed through the structure, implementation process and applicable regulations, experienced several obstacles in online activities and supporting facilities that had not been fulfilled. However, the indicators for the PHBS program in school settings can be implemented through various adaptations of the activities that have been carried out.
MSMEs Upgrade with The Concept of Green Accounting and Digitalization (Study Literature Review)
Authors: Kurnia Sari Ayu , Kesuma Sambas Ade , Muda Iskandar
Published: May 2023

MSME is one of the products belonging to the small and environmentally friendly industrial sector. The concept of MSMEs related to green accounting and digitization is still not optimal, so this can be used as research. The purpose of this research is to see how the concept of green accounting and digitization of accounting for MSMEs is developing. To show macro and micro perspectives on green accounting, an issue related to the environment and ecological science, and the sustainable management of natural ecosystems. This research method was carried out using the study literature review method. The population used is 1,603 units of the MSME sector in the city of Medan. The results of this study state that SMEs will be able to upgrade to a high level by applying digitalization to their market place and the concept of green accounting which can provide income for the environment and MSMEs.
The Effect of Service Quality and Price Perception on Patient Loyalty Mediated by Patient Satisfaction
Authors: Fathillah Muhammad Ichsan
Published: May 2023

This study aims to see the effect of service quality and price perception on patient loyalty which is mediated by patient satisfaction. Respondents in this study were patients who came to the PUSPIPTEK Medical Center. Hypothesis testing was carried out using quantitative research with a sample size of 100 respondents. Data were obtained through electronic questionnaires that were digitally administered to respondents. The analysis technique used is Partial Least Square - Structural Equation Modeling (PLS-SEM) using the SmartPLS program. Based on the results of data processing and data analysis it was found that there is a significant effect of service quality on patient satisfaction, there is an effect of Price Perception on patient satisfaction, there is no effect of service quality on patient loyalty, there is a significant effect of price perception on patient loyalty, indirectly there is the effect of service quality on patient loyalty mediated by patient satisfaction, and indirectly there is a significant effect of price perception on patient loyalty by mediating patient satisfaction. The PUSPIPTEK medical center is one of the existing ones in the South Tangerang area. With this, the management can update other health service measures, such as the practice of specialist doctors along with increasing consumer desires and increasing consumer needs.
Work Life Balance Model, Work Stress and Performance of Millennial Generation Online Taxibike Drivers
Authors: Ghani Muhammad Alfa , Muttaqiyathun Ani
Published: May 2023

The characteristics of the millennial generation are different from those of the previous generation. It is important to research the performance of those who currently dominate the world of work, especially the unprecedented work of online motorcycle taxi drivers. The purpose of this study is to determine the balance and work stress on the performance of millennial generation online motorcycle taxi drivers. This study used a quantitative approach, with the subject of online motorcycle taxi drivers, where the population is difficult to know. The sample was determined using the Lameshow formula so that a sample of 100 respondents was obtained. Teknik purposive sampling is used with the criteria of married drivers and classified as millennial generation. Data collection using questionnaires in the form of google forms is distributed directly to online motorcycle taxi drivers. Data analysis techniques use multiple linear regression analysis.  The results showed that there was an effect of work life balance on performance, but on the contrary,  there was no effect of work stress on performance.
Legal Politics Implementing Jakarta Bay Spatial Arrangements in The Framework of Realizing Good Governance
Authors: Appe Appe , Suganda Atma
Published: May 2023

The aim of this research is to analyze the regulatory authority of the Provincial Government of DKI Jakarta in the spatial management of the Jakarta bay, as well as to analyze and find legal solutions regarding ideal legal politics in the spatial arrangement of the Jakarta bay which can create good government. This study uses a normative juridical legal approach. The data collection in this study used the technique of library research, observation and field research originating from primary, secondary and tertiary legal materials which were analyzed qualitatively normatively. The results of the study show that the Provincial Government of DKI Jakarta can propose the establishment of a special area in its territory to the Government which can be managed directly by the Central Government or can be managed jointly between the Central Government and the Provincial Government of DKI Jakarta in accordance with statutory provisions. The study of the ideal legal politics in the spatial arrangement of the Jakarta Bay, then this cannot be separated from the juridical considerations that form the basis for the formation or making of a statutory regulatio..
Assessment Professional Functions in Land Procurement of National Strategic Projects in Realizing Legal Certainty Principle
Authors: Adrianto Henricus Judi , Emirzon Joni , Terhupeiory Aartje , Nainggolan Bernard
Published: May 2023

This study also aims to analyze the application and completion of consignment in land acquisition for general interests in terms of the perspective of judicial decisions. The data collection procedures used in this study were questionnaires, observations, interviews, documentation. Data analysis techniques in this study use qualitative analysis that is inductive, which is an analysis based on the data obtained, then a certain relationship pattern is developed. From various studies, this research concludes that the trigger for conflicts related to land acquisition often occurs because the value of compensation / compensation given to affected communities is not given properly and fairly, lacks transparency and harms the community. In addition to problems related to injustice, it is stated that some land acquisitions carried out in Indonesia have not fully involved community participation, lack of counseling/socialization processes and meaningful public consultations on land acquisition plans carried out by parties who need land to the community, have not compiled land acquisition planning documents that are studied in depth in accordance with the environmental, socio-economic conditions of the community  and the lack of involvement of parties/agencies that have authority related to land acquisition since the initial planning process.
Justice as A Law Sacrament: Measuring Justice in Pancasila Philosophy
Authors: Apaut Yosep Copertino , Neonbeni Randy Vallentino
Published: May 2023

Indonesia as a plural country with a diversity of ethnicities, religions, races, customs, cultures, regional languages, will really rely on a single nation principle, namely Pancasila with the logical consequence that every aspect of its life will be governed by Pancasila which is chaired by the state through its tool, namely the government. fully sovereign. This means that all complex life of society is entrusted to the State, including in the field of law to achieve essential justice. In this regard, the state is obliged to carry out the orders of Pancasila through the constitution, which is used as a guideline and benchmark in every practice of state administration, including aspects of law enforcement that are just for all Indonesian people.
Tópicos multidisciplinarios de Investigación 2022.
Authors: Acevedo Sánchez Ismael , Castillo Trejo Alfredo
Published: May 2023

Esta publicación fue realizada para la Universidad Tecnológica de Tula-Tepeji, se inició su proceso editorial en diciembre de 2022 y terminó en abril de 2023; tiene como política editorial un proceso de revisión por pares doble ciego, donde los artículos son remitidos a académicos especializados en el tema. Asimismo, nuestro Comité editorial de iQuatro Editores determina si el artículo es aceptado o rechazado, cuidando su originalidad y calidad.
PENGARUH KEMISKINAN, INFLASI, TENAGA KERJA, EKSPOR, KONSUMSI DAN INVESTASI TERHADAP PRODUK DOMESTIK REGIONAL BRUTO SUMATERA UTARA
Authors: Lowie Jefferson , Harahap Sunarji , Elidawati Elidawati , Goh Thomas Sumarson
Published: May 2023

The purpose of this study was to determine and analyze the effect of poverty, inflation, labor, exports, consumption and investment on the gross regional domestic product of North Sumatra. The population of this study is 33 data on poverty, inflation, labor, exports, consumption, investment and gross regional domestic product of North Sumatra for the period 2017-2020. The sample of this study is 33 data on poverty, inflation, labor, exports, consumption, investment and products. North Sumatra's gross regional domestic product for the period 2017 - 2020. The data collection technique is based on the documentation on the data presented on the website https://sumut.bps.go.id/site/selectdata.html. This study uses multiple linear regression analysis. The results showed that poverty had no effect on the grossw regional domestic product of North Sumatra. Inflation has no effect on the gross regional domestic product of North Sumatra.
Studi Kasus: Asuhan Kebidanan Kehamilan Pada Ny.A Dengan Mola Hidatidosa
Authors: Hamidiyanti Baiq Yuni Fitri , Cory'ah Fitra Arsy Nur , Gumilang Pratiwi Intan , LM S. Nidaa’an Khafiya
Published: May 2023

Latar Belakang: Angka kematian ibu (AKI) masih sangat tinggi, sekitar 295.000 wanita meninggal selama dan setelah kehamilan dan persalinan. Menurut kemenkes RI Tahun 2020, jumlah kematian ibu pada tahun 2020 menunjukan 4.627 kematian di Indonesia. Berdasarkan penyebab, sebagian besar kematian ibu pada tahun 2020 disebabkan oleh pendarahan (termasuk mola hidatidosa). Prevalensi mola hidatidosa di Asia menunjukan 1:120 kehamilan. Di Inonesia sendiri didapatkan kejadian mola hidatidosa pada 1:85 kehamilan. Berdasarkan laporan tahunan RSUD PATUT PATUH PATJU Gerung tahun 2020 ditemukan kasus Mola Hidatidosa sebanyak 12 kasus. Pada tahun 2021 bulan Januari sampai dengan September tercatat sebanyak 7 kasus.Tujuan: Menerapkan asuhan kebidanan pada ibu hamil dengan Mola Hidatidosa, menggunakan pendekatan manajemen kebidanan secara komprehensip. Metode: Jenis penelitian yang digunakan dalam studi kasus ini adalah penelitian deskriptif dengan menggunakan data primer dan sekunder dari anamnesa, pemeriksaan fisik, pemeriksaan laboratorium, dan rekam medik. Hasil: Pengeluaran jaringan Mola Hidatidosa dilakukan dengan Aspirasi Vaccum Manual. Kesimpulan: Pemberian penatalaksanaan sudah sesuai dengan teori dan prosedur
 
Background: The maternal mortality rate (MMR) is still very high, around 295,000 women die during and after pregnancy and childbirth. According to the Indonesian Ministry of Health in 2020, the number of maternal deaths in 2020 showed 4,627 deaths in Indonesia. Based on causes, the majority of maternal deaths in 2020 were caused by bleeding (including hydatidiform mole). The prevalence of hydatidiform mole in Asia is 1:120 pregnancies. In Indonesia, the incidence of hydatidiform mole is 1:85 pregnancy. Based on the annual report of the PATUT PATUH PATJU Gerung Hospital in 2020, 12 cases of Mola Hidatidosa were found. In 2021 from January to September there were 7 cases. Objective: Applying midwifery care to pregnant women with Mola Hidatidosa, using a comprehensive midwifery management approach. Method: The type of research used in this case study is descriptive research using primary and secondary data from anamnesi s, physical examination, laboratory examination, and medical records. Results: Hydatidiform mole tissue was removed by manual vacuum aspiration. Conclusion: Provision of management is in accordance with theory and procedures.
A Study on Writing Strategies used by Students of Different Levels of Proficiency at A University in Vietnam
Authors:   Dai Nam University - Hanoi, NHUNG NGUYEN THI
Published: May 2023

The primary purpose of the study was to measure the use of writing strategies of participants. The secondary purpose aims at finding out strategies mostly used by high level of proficiency students compared those of level of proficiency at different stages of writing, namely before, during and after the writing assignment. The study was conducted among 137 English majored students. The findings reveal that before writing high proficiency students used strategies more often than the other two groups, namely medium and low levels of proficiency. The mean of before writing strategies uses were M=3.48; M=2.30; M=1.98 respectively. The mean of during writing strategies uses were M=3.36; M=3.03; M=2.57 respectively. The mean of after writing strategies uses were M=3.55; M=1.99; M=2.06 respectively. Among the group of Before Writing Strategy (BWS), Students with high proficiency level often discuss what they were going to write with other students or with teacher before they write (M=3.86). The figure for low level of proficiency students was M=1.50. The high level students also do extra study outside the classroom to improve his/her writing (M=3.86), while the low level students was M= 1.32. The high level students reported that they think of the relationships between what they already know and new things that they learn (M=3.71). The use of this strategy for low level students were only M=1.68. Among the group of During Writing Strategy (DWS), students with low proficiency use native language first and then translate it into English most often (M= 3.86). The high proficiency students did not use this strategy while writing (M=1.57). The low proficiency students also reported that they used dictionary a lot when they write (M=3.25), the figure for high proficiency students was only M=1.29). Another strategy that was employed by most low level students was “I use a grammar book to check things I am not sure about when I write” (M=3.97) while the high level students used this strategy at low frequency (M= 1.29). Among the group of After Writing Strategy (AWS), students with high proficiency reported that they often go back to his/her writing to edit the grammar, vocabulary, spelling, and punctuation. (M=3.81) compared with M=2.80 of low proficiency students. High proficiency students also often record the types of errors he/she has made so he/she does not keep making the same (M=3.80), while the figure for low proficiency students were M= 1.20.
Analysis of Business Development Strategies for know Small Business in Kediri
Authors:   Faculty of Economics, University of Pawyatan Daha, Kediri, Hanggondosari, SE, MM Sri Utami
Published: May 2023

This research is motivated by the fact that internal and external factors in a business are important components in the development of small businesses in rural areas. The main objective of this study was to determine the internal factors that became strengths and weaknesses and external factors that became opportunities and threats in small businesses in rural areas. After knowing the strengths, weaknesses, opportunities and threats, you can analyze business development strategies for small businesses in rural areas. This study used small tofu entrepreneurs in Tinalan Village, Pesantren District, Kediri Regency, as the sample using Simple Random Sampling on all tofu small entrepreneurs as the population with a determination of 30 respondents. This data is analyzed using the Internal External (IE) Matrix and Market Share Growth Matrix. Based on the results of the research, it shows the following conditions: (1) That the business development that needs to be done to determine the strategy for the small business is an Intensive Strategy that focuses on increasing the competitive position through existing products. (2) Whereas the test results of market share growth analysis show a value above the benchmark, which is 10%. Thus the results of this study can be used as a policy basis in knowing internal and external environmental aspects so that they can analyze development strategies for small businesses in rural areas.
The Effect of Non Performing Loan (NPL) and Loan to Deposit Ratio (LDR) Return on Assets (ROA) in PT. Bank Sulselbar
Authors: Vira Ayustina  , Chalid Imran Musa  , Nurman  , Anwar  , Ahmad Ali
Published: May 2023

The purpose of this research is totest and analyze the effect of Non Performing Loans (NPL) and Loan to Deposit Ratio (LDR) on Return On Assets (ROA) at PT. Sulselbar Bank. The techniques for collecting secondary data are obtained from the Financial Data at PT. Sulselbar Bank. The population is the financial statements at PT. Bank Sulselbar from August 2017 to December 2021, and the samples taken are monthly data for 4 (four) years and 5 (five) months. So, the amount of data obtained is 53. The results of the research have been tested on classic assumptions such as the assumption of normality, the assumption of multicollinearity and the assumption of heteroscedasticity. By applying multiple linear regression techniques in the process of analyzing the data. The results showed that partially Non Performing Loans (NPL) had a negative and insignificant effect on Return on Assets (ROA) and Loan To Deposit Ratio (LDR) had a positive and insignificant effect on Return on Assets (ROA). Simultaneously Non Performing Loans (NPL) and Loan to Deposit Ratio (LDR) have a positive effect