bluuebunny/crossref_metadata_2025 huggingface dataset:
A Bioinformatics Analysis of FAM3A to Identify its Potential Role as a Biomarker in Liver Hepatocellular Cancer
Authors: Raza Syed Hussain
Published: August 2024

Liver hepatocellular cancer (LIHC) is positioned as the third cancer with the highest mortalities worldwide, and high mortalities are associated with late diagnosis and recurrence. This study advances bioinformatics analysis of FAM3A expression in LIHC to evaluate its potential as a prognostic, diagnostic and therapeutic biomarker. Bioinformatics tools such as UALCAN, GEPIA2, KM plotter, TIMER2 and cBioPortal are employed to conduct analysis. Initially, the expression analysis revealed up-regulation of FAM3A in LIHC based on various variables. Further, the study observed that FAM3A methylation regulates expression as variation in methylation level of FAM3A was assessed in LIHC. Moreover, this over-expression of FAM3A results in poor overall survival (OS) in LIHC patients. All of these proposed that FAM3A has a role in the progression and development of LIHC. While examined association of FAM3A expression and infiltration level of CD8+ T cells in LIHC patients using TIMER2 revealed that FAM3A has a positive correlation with purity in LIHC that highlights the molecular landscape. Analysis of genetic alteration revealed minute role of FAM3A in LIHC still provides valuable insight. Overall, our findings reveal that FAM3A has potential as diagnostic, therapeutic and prognostic biomarkers in LIHC.
Optimization of Polysaccharides Extraction from Physalis alkekengi L. Peel and Its Effect on the Expression of Inflammation-Related Proteins in SW620 Cells
Authors: Shao Dan , Hao Chengxin , Mei Yubi , Xu Jiaxin , Wang Tianjiao , Yang Wei , Wu Jiamei
Published: August 2024

Objective: To establish an optimized aqueous extraction process for polysaccharides from Physalis alkekengi L. peel and to preliminarily explore its in vitro anti-inflammatory activity against colorectal cancer SW620 cells. Methods: A single-factor test combined with orthogonal test analysis was used to evaluate the effects of the material-to-liquid ratio, extraction temperature, and extraction time on the yield of polysaccharides from Physalis alkekengi L. peel. The antioxidant activity of the polysaccharides was assessed by analyzing their free radical scavenging ability in vitro, and the anti-inflammatory effect was evaluated using SW620 cells. Results: The optimal extraction conditions were a material-to-liquid ratio of m(g):V(mL) = 1:30, an extraction temperature of 100°C, and an extraction time of 40 minutes, with a predicted polysaccharide yield of 25.7%. The polysaccharides from Physalis peruviana peel effectively scavenged DPPH, superoxide anion, and hydroxyl radicals. After treatment with Physalis peruviana polysaccharides, the levels of IL-1β, IL-18, and TNF-α in the cell culture medium were significantly reduced, and the phosphorylation level of P65 protein in SW620 cells was decreased. Conclusion: This extraction method is stable and reliable, and the prepared Physalis alkekengi L. polysaccharides exhibit significant in vitro antioxidant and anti-inflammatory activities. This study provides a theoretical basis for developing drugs for the prevention and treatment of colorectal cancer.
Tríplice Fronteira sul: um estudo da entrada de ilícitos transfronteiriços
Authors: Lacerda Martins Júlio César , de Franciscis Ramos Carlos Eduardo , Coelho de Oliveira Edwardo Coelho de Oliveira
Published: August 2024

As fronteiras são regiões singulares que requerem atenção permanente dos Estados. Atualmente, o debate sobre as fronteiras admite dois prismas: bordier e frontier. O primeiro é relativo às questões geopolíticas e o segundo, está relacionado às questões de segurança. O Brasil é o quinto país em extensão territorial do mundo e ocupa cerca de 47% da América do Sul. A existência de cidades-gêmeas em Tríplices Fronteiras é uma marca fronteiriça brasileira. O objetivo deste estudo é apresentar o perfil da entrada de ilícitos na Tríplice Fronteira entre Brasil, Paraguai e Argentina. Desta forma, definiu-se a problemática de pesquisa deste artigo: qual é o perfil de apreensões de ilícitos na Tríplice Fronteira na última década (2011-2021)? Trata-se de uma pesquisa qualitativa-quantitativa, exploratória e literária por meio de uma revisão bibliográfica narrativa, em que se utilizou os estudos versando sobre a apreensão de ilícitos na Tríplice Fronteira como critério de inclusão e as publicações da referida temática, anteriores a 2011, como critério de exclusão. Concluiu-se que houve uma mudança no perfil de apreensões de ilícitos transfronteiriços nos últimos 10 anos, com maior destaque para o contrabando do cigarro, que alcançou cifras até maiores do que o tráfico de drogas.
Editorial
Authors: Pereira Rezende Lucas
Published: August 2024

v.11,n.1 (2024)
How the Soft-Side of Change Can Better Prepare the Hearts and Minds of Employees?
Authors: Sayyadi Mostafa , j Provitera Michael
Published: August 2024

Change has been posited as important today by some of the top journals such as Harvard Business Review, California Management Review, Muma Business Review, and MIT Sloan Management Review, but what exactly does the change mean to you? For example, the COVID-19 change is certainly tantamount to many people’s minds. That change is so broad, readers view it as changing everything from the price of food to the remote working environment. Many business leaders and scholars sanctify organizational change. But why? One reason is that organizational change is one of the most difficult management issues to grasp, and while executives are contemplating change they are being usurped by their boss or by the competition. When managers decide to lead change, they face many problems such as countless tensions or opposition from employees. Successful change requires leading the hearts and minds of employees. Only then, will leaders get buy-in. In fact, if the employees do not buy into the change with their hearts and minds and do not accept it, real change will not happen. We address the vital question today: 'How can managers prepare the hearts and minds of employees for change?' To answer this question, executives need to manage the soft side of change. Our experience of more than 20 years of management consulting in Australia and the rest of the developed countries speaks to the most important factor in preparing the hearts and minds of employees. Have them accept the idea that change is mandatory to remain competitive and will not eliminate their jobs and they will buy into the change.
Impactos ambientais causados pelo ciclo de vida de painéis fotovoltaicos
Authors: Costa Higor Rodriges Silva , Camargo Pedro Luiz Teixeira de , Alves Felipe da Silva
Published: August 2024

O crescimento econômico aliado ao aumento pela demanda de energia provocou alto crescimento nas taxas de emissão de gases do efeito estufa, visto que as principais matrizes energéticas para geração de eletricidade são oriundas de combustíveis fósseis. Buscando a solução desses problemas, a geração de energia por meio de fontes renováveis ganhou ampla relevância no cenário mundial, possibilitando a matriz energética fotovoltaica, que consiste na conversão direta da luz em eletricidade, alcançar posição de destaque em relação a outras fontes. Os módulos fotovoltaicos têm vida útil entre 25 a 30 anos e possuem uma grande diversidade de materiais em sua composição. Sendo assim, a presente pesquisa realizou um estudo a respeito dos impactos ambientais causados pelos painéis fotovoltaicos. Seus dados foram provenientes de pesquisas bibliográficas que relatam acerca do tema em questão ocasionados pela produção, instalação, operação e descarte inadequado de painéis fotovoltaicos. Após a coleta dos dados, foram desenvolvidas tabelas, com a identificação e classificação dos impactos apontados pelos principais autores. Baseado nos tópicos discutidos ao longo do trabalho, concluiu-se que a energia fotovoltaica, apesar de seus conhecidos benefícios, apresenta impactos relevantes ao meio ambiente.
 Palavras-chave: Eletricidade. Módulos. Matriz energética.
 
Environmental impacts generated by life cycle of photovoltaic panels
Abstract
Economic growth combined with increased energy demand has raised greenhouse gas emission rates, since the main energy matrices for electricity generation come from fossil fuels. Seeking a solution to this problem, the generation of energy through renewable sources has gained wide relevance on the world stage, enabling the photovoltaic energy matrix, which is the direct conversion of light into electricity, to reach a prominent position in relation to other sources. Photovoltaic modules have a useful life between 25 and 30 years and have a great diversity of materials in their composition. Therefore, the present research carried out a study on the environmental impacts caused by photovoltaic panels. Its data came from bibliographic which report on the subject in question derived from the production, installation, operation and inappropriate disposal of photovoltaic panels. After collecting the data, tables were produced, with the identification and classification of the impacts pointed out by the main authors. Based on the topics discussed in the present work, it was concluded that photovoltaic energy, despite its known benefits, has relevant impacts on the environment.
Keywords: Electricity. Modules. Energy matrix.
REVOLUTIONIZING GRAPHIC DESIGN: THE SYNERGY OF AI TOOLS AND HUMAN CREATIVITY
Authors: Das Subrato , Rani Poonam
Published: August 2024

Over the last few years, the rapid development of artificial intelligence has initiated new opportunities offered to designers. In the area of graphic design, multiple AI tools are available that enable users to benefit from the capabilities of this technology. Currently, illustrators, photographers, web designers, and other visual creators may use AI-driven applications and support to enhance the quality and variety of their works. Not only does this process help save a lot of time, but it also opens a variety of creative opportunities that one would not have thought of without technology.Human designers' role becomes curator and directional advisor which puts more emphasise to strategy and visual creativity. One of the proposals is to figure out the ethical rules, revaluate existing education, and somehow make sure that human kind is protected. The future picture is the AI and human creativity complementing each other, to create new innovations in the field of design.
Low Power CMOS Differential Amplifiers through ACM Model: Process Variations and Yield Prediction
Authors: Vijay Ashish , Duari Chusen , Garg Lokesh , Singh Amit Kumar
Published: August 2024

Statistical techniques are regularly used to predict the performance of electronic systems. Process variations which account for the uncertainties in material parameters at the time of fabrication adversely affect the yield of analog integrated circuits. The statistical analysis of variations in key output parameters of an analog circuit due to variations in the fabrication parameters for yield prediction isan essential step in analog chip fabrication. In this work, we use a rigorous statistical approach to examine the performance of atypical analog circuit. We have designed a two stage CMOS differential amplifier configuration at 65 nm technology usingACM model parameters to examine the yield under process variations. We employ three different Monte Carlo models(uniform, gaussian, worst-case) to examine the statistical variation in key performance parameters of the designedCMOS differential amplifier. Variations in key differential amplifier parameters, maximum gain, gain margin and phasemargin have been reported under 10% variations in typical process parameters. Maximum variability is observed in case ofthe worst-case distribution while the minimum variability is found in case of Gaussian distribution. The results showsignificant impact of process variation on the yield of the designed CMOS differential amplifier. In the case of gaussiandistribution, the standard deviation for gain margin(dB), phase margin (degrees) and maximum gain(dB) is found to be 11, 25and 24 respectively.
The Dualism of Reconciliation Law After Triple Talaq Outside the Court
Authors: Zein Nita Azita , Yazid Imam , Firmansyah Heri
Published: August 2024

Revocation of divorce (ruju’) generally occurs after a husband's first or second pronouncement of divorce (talaq). However, after the third pronouncement (third talaq), Islamic jurisprudence (fiqh) prohibits revocation unless specific conditions are met. This study examines the legal dualism regarding rujuk after third talaq, especially when talaq is pronounced outside the Court. Unlike the four major fiqh schools, Indonesian law requires talaq to be declared in a Religious Court session, as stated in Article 5, Paragraph (1) of the Compilation of Islamic Law. This research aims to comprehensively understand the dualism of the reconciliation law after divorce that often occurs outside the Court. Using normative legal research with a qualitative approach, the findings suggest that Muslims should pronounce talaq and ruju’ in front of a Religious Court to comply with Indonesian law and ensure legal protection and administrative recording of marriage and divorce. The study recommends that the Religious Court consider talaq pronounced outside the Court if substantiated with witness testimony.
The Law Politics in The Reformulation of Interfaith Marriage in Indonesia
Authors: Hadiati Teti , Makrum Makrum
Published: August 2024

The issues explored in this study revolve around whether interfaith marriages align with the philosophical values of Indonesian marriage law, and why the validity of such marriages remains contentious in Indonesian legal context. In connection with the principle of ongoing legal conditions and public order, the implementation of marriage registration signifies a recognition of interfaith marriages, which the community accepts as a natural reality. This research employs both normative legal analysis and quantitative sociological research methods. The methodology evaluates matters concerning public order, legal compliance, and the continuation of existing legal situations or acquired rights. Based on this research, it was concluded that interfaith marriages are deemed inconsistent with the philosophical principles of Indonesian marriage law rooted in religious doctrine. Such marriages could potentially undermine the longstanding efforts in Indonesian marriage law legislation aimed at upholding public order. Consequently, registrations conducted by civil registry offices lack authoritative legal status and are merely administrative procedures.
Overmacht: Analisis Yuridis Penundaan Pelaksanaan Prestasi Akibat Pandemi Covid-19
Authors: Tauratiya Tauratiya
Published: August 2024

On March 14, 2020, the government of the Republic of Indonesia declared the Covid-19 pandemic a National Disaster. The entire community was urged to stay at home or work remotely. This situation has rendered the daily activities of both the community and the government, including schooling, work, trade, and others, ineffective and delayed. Furthermore, it has also impacted corporate activities at both national and global levels. Many businesses have been disrupted due to the implementation of Large-Scale Social Limitations policy, thereby preventing companies or individuals from fulfilling their previous agreements. This study investigates whether the Covid-19 pandemic can serve as a legitimate reason for individuals or companies to delay the fulfillment of their obligations, considering it as a force majeure, and its legal implications. This research adopts a qualitative-library approach with a juridical-normative perspective. The findings indicate that force majeure is akin to the concept of overmacht, signifying a situation where the debtor cannot be held accountable due to circumstances beyond their control and not resulting from negligence. The concept of overmacht is governed by Article 1244 and Article 1245 of the Civil Code. The Covid-19 pandemic falls under the category of force majeure, thus enabling debtors to invoke it as a valid reason to postpone or refrain from fulfilling their obligations as per agreements, provided they can demonstrate that their failure to comply is not attributable to them, but rather to unforeseeable and inevitable circumstances.
Dilemma Executive Control: Development of Regional Regulatory Canceling Models
Authors: Barus Sonia Ivana
Published: August 2024

The Law Number 23 of 2014 concerning Regional Government clearly states that the Minister of Home Affairs with instruments in the form of a Ministerial decree bears the authority to annul regional regulations which deemed contrary to the provisions of the higher laws, public interests and/or decency. However, the Constitutional Court (MK) through Decision No. 137/PUU-XIII/2015 and MK’s Decision No. 56/PUU-XIII/2016 has restrained the authority of the Minister of Home Affairs to annul the Regional Regulation (perda). This is an interesting discussion, some consider that it actually weakens the role of the central government to control local governments, on the other hand, justifying that authority belongs to the Supreme Court. Interesting problems of this research is what is the actual relations of authority between local and central government? Then what is the ideal model for the annulment of regional regulations so that the central government has a role in exercising control (executive control) of regional regulations before and after regional regulations come to be applied? This research was conducted using a normative juridical method, namely a research method that refers to the norms of legal norms contained in statutory regulations. This research resulted that there is a decentralization and decencentration relationship between the central and local governments. In order to anticipate these problems, the ideal model for cancellation of regional regulations to accommodate the authority of the central government is to separate regional regulation according to the content or material
Family Harmony in Implementation Of Pohutu Moponika Tradition in Gorontalo City in The Perspective of al-Thufi’s Maslahah
Authors: Oktora Nency Dela , Putra Muhammad Yusuf , Mahmudah Nurul
Published: August 2024

This study is aimed at discussing the system and procession of indigenous Mohammed Moponika marriage in creating the value of family harmony in Gorontalo City based on Al-Thufi’s perspective on maslahah. This study used in this research is the type of field research with descriptive method of phenomenological approach. The results of this study conclude that in the traditional procession of the Pohutu Moponika Marriage accommodates many aspects of benefit in an effort to give birth to a harmonious family. The value of benefit intended for the Pohutu Moponika tradition is to gain or gain benefits and reject harm in order to maintain goals syara‘. Although it is not regulated in the texts and does not seem to be in accordance with the provisions of the texts, the customary process of the Pohutu Moponika Marriage in Gorontalo does not aim to destroy religion. On the contrary, it is actually intended for the benefit of the bride and groom so that they can navigate a harmonious domestic life. Therefore, it is included in the maslahah category in accordance with the concept of al-Thufi. Basically, Allah Swt establishes the rules of command and prohibition that are essentially only intended for the good and benefit of humans.
Accuracy Test of Supermarket's Mushola Qibla Direction In Cirebon City
Authors: Samsudin Samsudin , Kusdiyana Kusdiyana , Ramadhan Rizal
Published: August 2024

This study aims to answer the questions that become the formulation of the problem “How is the method of measuring the Qibla direction of the supermarket prayer room in Cirebon City” and “How to analyze the accuracy of the supermarket prayer room Qibla direction in Cirebon City.” This study uses qualitative research; the data collected uses observation, interviews, documentation, and literature study. They were then analyzed by the descriptive analysis method in narration. The results of this study: that the Qibla direction of the supermarket in Cirebon City has all measured the Qibla direction. The method of measuring the Qibla direction was carried out by the musala supermarket, where the author’s research uses the Qibla compass and the Qibla direction application on the smartphone. Of course, using the Qibla direction application on a smartphone is an inaccurate method. This method’s method is partly an error in determining the Qibla direction. Due to his ignorance of astronomy in measuring the Qibla direction and ignorance of the magnitude of the Qibla direction angle in the Cirebon City area, resulting in the Qibla direction of the supermarket in the Cirebon City area experiencing a wrong Qibla direction.
Implementation of Corporate Social Responsibility (CSR) and Community Response around the Company PT. Bumi Sari Prima Pematang Siantar in the Perspective of Islamic Business Ethics
Authors: Asterina Lidya , Rokan Mustafa Kamal , Marliyah Marliyah
Published: August 2024

This study aims to deeply analyze about: 1) PT. Bumi Sari Prima Pematang Siantar, 2) Implementation of PT. Bumi Sari Prima Pematang Siantar to the Community and the Response of the community around the PT. Bumi Sari Prima Pematang Siantar, and 3) Shariah Enterprise Theory (SET) Review of PT. Bumi Sari Prima Pematang Siantar. This research is a field research with a descriptiveinductive type of qualitative research. The subjects of this study were the community and employees of PT. Bumi Sari Prima Pematang Siantar. The results showed that PT. Bumi Sari Prima Pematang Siantar is carried out in the form of (1) Giving Cash to the surrounding community, (2) Handing over assets / grants to be used, (3) Providing the company's products to the community every year, (3) Providing Free Services to people who have interests, (4) Allowing the use of company facilities for community activities, (5) Recruiting workers in the surrounding environment (6) providing social assistance, (7) Management and Protection of the environment, (8) Human Resource Development. Implementation of PT. Bumi Sari Prima Pematang Siantar was well distributed, and received a positive response from the community around the company for the company's CSR program. Shariah Enterprise Theory review of the implementation of PT. Bumi Sari Prima Pematang Siantar when viewed in terms of objectives, that this program is in accordance with the principle of sharing Adil, Maṣlaḥah and Raḥmatan lil‟alamῑn
Qawaid Fiqhiyah's Review of Buying Shoes With a Paid Lots System at Toidiholic Store Bandar Lampung
Authors: Jayusman Jayusman , Hidayat Rahmat , Febriansyah Rizki Zulu
Published: August 2024

In the practice of buying and selling at the Toidiholic Store there is one system, namely a paid lottery. This is done in the sale and purchase of limited edition shoes with a large demand. The focus of this research is how Qawaid Fiqhiyah analyzes the practice of buying and selling shoes with a paid lottery system at the Toidiholic Store Bandar Lampung. This study concludes that this lottery is a lottery that is permitted by Islamic law because it is carried out solely to create a sense of justice and prevent chaos and prevent wholesale buying of shoes if sold normally or without a lottery. Although the cost of the lottery coupon is sold for Rp. 20,000, - but the fee is still within reasonable limits as a registration or administration fee for holding a lottery activity, considering that the benefit element in this lottery is greater than the harmful element.
Development Strategy of PPM al-Kautsar Micro Waqf Bank in Lima Puluh Kota Regency
Authors: Nurhafiani Nurhafiani , Tarigan Azhari Akmal , Yafiz Muhammad
Published: August 2024

This research aims to find out and analyze the development strategy of the PPM Al-Kautsar Micro Waqf Bank in the Lima Puluh Kota Regency. The data analysis technique used is the SWOT analysis method (Strenght, Weakness, Opportunity, Threats). Based on the results of the SWOT matrix analysis, it is known that the strategy that can be carried out in developing a Micro Waqf Bank is stratetgi SO by using all strengths to take advantage of existing opportunities. The strategy is consistency of low mentoring services (ju'alah, without collateral and interest by utilizing government restructuring programs, utilizing the role of kyai in establishing good cooperation and building trust with institutions, local governments, the community socializing the existence of Micro Waqf Bank, carrying out Halmi routines during a pandemic virtually and directly by complying with health protocols in providing education, direction, education to customers, improving the quality of services and products even though it already exists with a ball pick-up system, optimizing the empowerment of mentoring through digital so that customers can survive during the pandemic despite social restrictions but empowerment continues to run. The strategy of developing Micro Waqf Bank is to use Micro Waqf Bank digitalization in providing virtual education, promoting customer products through e-commerce and social media, utilizing the role of kiyai in socializing BWM programs to the community
Reconstruction of the Kafaah Concept in Marriage
Authors: Suwarjin Suwarjin
Published: August 2024

Kafaah in marriage aims to create a complete and harmonious family. However, the old construction of kafaah contains discriminatory and problematic nuances. This can be seen from the criteria for kafaah, which are all physical-material, except for religion and piety. Humans are polarized into primordial partitions: beautiful-ugly, rich-poor, aristocratic-ordinary people, and free-slave. This polarization gives birth to discriminatory attitudes in society. In fact, Islam came to eliminate discriminatory social barriers. Through the maqâshid al-syâri`ah approach, this research seeks to reconstruct the concept of kafaah in several aspects, namely: reorienting the purpose of applying kafaah, repositioning kafaah rights, reviewing kafaah criteria and classifying kafaah. Maqâshid al-syâri`ah is presented here not as a doctrine to understand a particular context of Islamic law, but as a method to reconstruct the existing concept of kafaah. The goal is to produce a new concept of kafaah that is more substantive and humanist. From the results of the study, several conclusions were found. First, Kafaah legality is ijtihad because there are no valid texts found. Second, The construction of kafaah is influenced by the patrilineal system of Arab society. Third, Reconstruction of the concept of kafaah is carried out in two ways: (1) to include other criteria other than the seven criteria set by classical fiqh. (2) to compare the kafaah criteria between prospective husbands and prospective wives holistically. This things needs to be done to fulfill the current sense of justice and benef of the Muslim family.
Capítulo 1 - Hack na Ilha - contextos e conceitos
Authors: Souza Maria Isabel de Castro de
Published: August 2024

O capítulo retrata a trajetória do planejamento e execução do evento Hack na Ilha.
Capítulo 13 - IMPORTA^NCIA DA AVALIAC¸A~O DE PROJETOS POR UMA BANCA
Authors: Silva Branca Regina Cantisano dos Santos e
Published: August 2024

O capítulo destaca importância das bancas avaliadoras em maratonas tecnológicas no processo de construção de soluções inovadoras.
Capítulo 5 - CANVAS NA AREIA
Authors: Dias Jacques Fernandes
Published: August 2024

O Business Model Canvas (BMC), cuja possível tradução livre seria Quadro de Modelo de Negócios, é uma
ferramenta visual das mais utilizadas para se organizar e sintetizar um modelo de negócios. O Canvas, forma
sintética em que o BMC é normalmente referido, foi desenvolvido por Alexander Osterwalder (2004/2005)
em sua tese de doutorado onde apresenta a ideia de nove blocos de construção interligados que formam a
estrutura da atividade de uma empresa.
ROTA BIOCEÂNICA - Trajetórias de pesquisas inovadoras
Authors: DORSA ARLINDA CANTERO
Published: August 2024

Coletânea com textos de pesquisadores acerca da Rota Bioceânica.
Physical assets life cycle analysis in a food industry company - case study
Authors: João Pereira , Hugo Raposo , José Torres Farinha , J Edmundo de-Almeida-e-Pais
Published: August 2024

Monitoring the life cycle of physical assets (PA) implies addressing issues, such as PA’s energy efficiency and its replacement and definition of the most proper moment to renew. The goals of this article are: to present a characterization of energy sources and analyze the PA life cycle in a food sector company. First, it will be characterized the costs and the expenses of the organization’s energy sources, then, a study about the replacement of PA is presented; Traditional methods were used, such as economic life; The models that underlie it are discussed throughout the article, using actual data, for validation. Three methods for depreciation of PA are used: Linear Depreciation; Sum of Digits and Exponential. Other methods were used to determine the Economic Cycle for replacing PA: Uniform Annual Expenditure (MRAU); Minimizing the Average Total Cost (MCMT); and the MCMT-Reduced to Present Value (MCMT-RVP). The equipment of the study was bakery ovens (gas and electrical). Results and conclusions from the application of the methods used in the evaluation of these PAs are presented.
Stressors and coping mechanism among university students
Authors: Obatavwe Ukoba  , Diola Jonathan Dela Cruz  , Felicity Chinyere Odoh  , Matilda Ughwe Obi Ntumeonuwa  , Harriet Voke Akpughe  , Bosede Olubunmi Abotu  , Idiebise Efemena Beauty
Published: August 2024

Background: Stress is a global public health challenge that affects all ages especially students, it is responsible for major psychological breakdown and considered to be a silent killer. This study aimed at investigating the factors influencing stress among students with emphasis on socio-demographic profile, stressors, the effects and coping mechanism. Methods: Cross-sectional study design was utilized, with 230 subjects from different colleges at the Virgen Milagrosa University Foundation (VMUF), Pangasinan, Philippines; Data was retrieved using semi structured questionnaire and analyzed using the frequency distribution table, percentage, average mean, the weighted mean and the Pearson correlation coefficient (r). Result: The result showed that most respondents were 17-19 years old (38.3%), males (63.0%), Roman Catholic (64.3%), in the Allied Health Sciences (53.0%), 2nd year level (39.6%) whose parents were married (88.3%), mostly working in the private section (mothers: 33.0%) and (fathers; 51.3%), earning more than Php10,000.00 (48.7%) per month. Students are moderately stressed by various stressors as evident by the symptoms though developed various coping strategies however, these stressors could be physical, cognitive, emotional, and behavioral in nature. A relationship exists between age, sex, program of study, parent’s occupation and stressors, while the effects of stress is positively related to age, sex, religion, year level, marital status and parents occupation. Nevertheless there was a positive relationship with various coping mechanism. Conclusion: In conclusions, stress is an inevitable aspect of life with various effects on students, it is important to develop policies to evaluate the impact among students to avoid its consequences.
Bifocal medulloblastoma in an adult: A case report and review of the literature
Authors: Ghizlane Lembarki  , Otmane Soussi  , Mouna Sabiri  , Chorouk Mountassir  , Mohamed Labied  , Samira Lezar
Published: August 2024

Medulloblastoma is a malignant embryonal neuroepithelial tumour, rarely occurring in adults. The 2021 WHO CNS classification subdivided medulloblastoma into 4 groups based on molecular data, which may correspond to morphological features on imaging which are useful to recognise. Differential diagnoses in adults include ependymoma, hemangioblastoma, metastases, lymphoma, and high-grade glioma. We report the case of a double cerebellar medulloblastoma in a 34-year-old adult. We also highlight the differential diagnosis between medulloblastoma and other posterior cerebellar fossa tumours in adults providing practical elements to help suggest the most accurate diagnosis.
Social Construction of Academic Staff in Order to Create Professional Tutors
Authors: Prasetya Agus , Muwarni Juli , Purwitaningsih Ari
Published: August 2024

The Universitas Terbuka (UT) is the 45th State University in Indonesia which was inaugurated based on Presidential Decree No. 41 of 1984, with the Distance Learning System (SBJJ) model. The background of this research is the existence of a Research Gap, namely Tutor behavior in academic and administrative matters, such as for example Tutors are late in reporting tuweb result files, wrong assessment formats, limited IT mastery, this can cause disruption of tutorials. The purpose of this research is that lecturers who provide tutorials at UT, are professional academically and administratively. The problems that occur, many tutors at UT are only part-time, tutors often take permission, come late, collect files late, limited IT skills. This research is a qualitative research with descriptions in the form of narratives, stories, words on the subjects studied. While the novelty of this research is the understanding of assessment procedures and limited IT tutors, which is the cause of tutor problems. Data collection methods through observation, in-depth interviews, and documentation, data sources are obtained from primary data, namely tutors, while secondary sources are managers. Data analysis using the Miles and Huberman Interactive model which includes the stages of Data Collection, Data Reduction, Data Display, and Data Conclution and Data validity through triangulation both methods, sources, time. To explore the data, researchers used the study of L.Berger, T.Luckman's Social Construction Action theory, which is a theory that focuses on human social action in their social interactions in society. The results showed that the tutor construction process required academic and administrative social changes in tutors, to create a culture of quality, improve the quality of IT tutors.
The influence of social media short videos on Indonesians' English acquisition
Authors: Rakhmasari Dwi Lia , Pratiwi Berlin Insan
Published: August 2024

Social media is able to make an individual can get information, entertainment even jobs easily from their home. Learning language through social media become popular method for some people. Most famous social media platforms like Instagram, YouTube and TikTok use short video to give entertainment toward internet users. Using short video in social media tent learners to have unintentional or unplanned learning since many uses the applications almost every day. This study explained the impact of short video features on social media toward Indonesian English acquisition. It used a descriptive qualitative design. Descriptive qualitative design is research designed to obtain information about current status phenomena. The respondents consist of 494 Indonesian from different age 13-15 y.o, 16-18 y.o, 19-25 y.o, 26-35 y.o, >35 y.o Once the data was collected, all the answers were reviewed and analyzed, and conclusions formulated. This research found out that TikTok become the most popular application for Indonesian in the age 13-25 y.o followed by Instagram YouTube. Instagram become the most popular application for Indonesian in the age 26- > 35 y.o followed by TikTok and YouTube. This study found out that Indonesian believe the most significant impact toward their English are vocabularies. 94,1% respondents said that they get a lot of vocabularies from the video. 87.9% respondents said that since they get a lot of vocabularies from the video it is helpfull for themto easily understand about what they read.  Besides, 87.4% respondents said that they improve their speaking skill after watching short video. 83,6 % respondent said that they imitate what they hear from the short video on social media and unconsciously improve their listening skill after watching short video. The last,  69.8% respondents believe that their writing improve.
The Impact of School Activities on Road Performance Using PTV Vissim Software Simulation
Authors: Liana Ulwiyah Wahdah Mufassirin , Arif Muhammad
Published: August 2024

Movement increases along with population growth and economic improvement each year. However, this is not supported by adequate transportation infrastructure, which can lead to congestion and traffic flow. The congestion of Samarinda during peak hours. One such location is Anang Hasyim Street, which has several schools along the road, including Cordova Elementary and Junior High School, SMPN 1, and SMAN 1 Samarinda. Traffic is evident during school hours, both morning and afternoon, along with an increase the number of vehicles and pedestrians. This situation leads to decline in the performance of the road segment. Road performance is a quantitative measurement that describes the conditions occurring on a road segment and serves as a parameter for road performance. This primary data such as road geometric data, traffic volume, and vehicle delays over a specific segment length. Traffic surveys were conducted over three days Monday, February 26, 2024, and Friday and Saturday, March 1-2, 2024. The survey were from 06:30-07:30 WITA,12:00-13:00 WITA, and 15:30-16:30 WITA. The analysis is based on PKJI 2023 and traffic flow simulation using PTV Vissim. The traffic results for 2024 shows the capacity of Anang Hasyim Street is 2968.154 pcu/hour, with the highest vehicle on Monday being 3079.75 pcu/hour and a degree of saturation 0.501 (LoS type A), and side friction of 500.8 incidents per hour. Meanwhile, the forecast for 2034 indicates the capacity remains 2968.154 pcu/hour,  vehicle volume of 2202.83 pcu/hour, a degree of saturation 0.74 (LoS type B), and side friction of 563.33 incidents per hour.
Safety Study of Steel Structure of Weighbridge I Girder Against Hauling Trailer
Authors: Zulfikar Ryan , Noor Rusandi
Published: August 2024

Weighbridges play a vital role in coal mining operations. This study aims to calculate the stress range and fatigue life of steel bridge girder cross-sections. Using the numerical simulation method with the CSI Bridge v22 application, the maximum axial force of 197 kN and the minimum axial force of -74 kN were obtained. The axial force is determined from the first 3 spans of the bridge with a span length of 4 m. The span length of the weighbridge is 80 m. From the calculation, the maximum stress of 40.11 MPa and the minimum stress of -15.06 MPa were obtained, resulting in a stress range of 55.16 MPa. The nominal bending moment strength of the beam was found to be 0.56. This modeling allows the simulation of dynamic loads from a 400-tonne SDT truck (semi-trailer door tipper) passing over the bridge so that accurate stress range data can be obtained. Fatigue analysis was carried out using the Basquin equation using the constant C = 1x1012 and exponent m = 3, receiving a fatigue life of 0.006 (6.01x106) cycles assuming 30-40 hauling trucks passing over the weighbridge. The results of calculations and simulations obtained longitudinal and transverse profile dimensions of IWF 1000x520x18x31.
Regulatory Body Perspectives on Complaints and Disciplinary Action Processes for Health Professionals
Authors: Foong-Reichert Ai-Leng , Houle Sherilyn K.D. , Grindrod Kelly A.
Published: August 2024

Background:

Previous Canadian reviews of physician, pharmacist, and dentist disciplinary action have noted differences in discipline outcomes across professions and provinces. The objective of this study was to compare the disciplinary action process across provinces and professions, and to describe the perspectives of health professional regulatory bodies on the disciplinary action process.

Methods:

Participation from medicine, pharmacy, nursing, and dentistry registrars or complaints directors from 10 Canadian provinces was sought. One-on-one, semi-structured interviews were conducted by telephone or video call.

Results:

Nineteen interviews with regulators were conducted—8 pharmacy, 5 nursing, 5 medicine, and 1 dentistry. Complaints and discipline processes followed a similar overall pathway with some differences. Differences in process were largely due to differences in health regulation legislation and were noted across professions, across provinces, and within a province. Participants tended to be more aligned with regulators within their province rather than regulators of the same profession across the country.

Conclusion:

To our knowledge, this paper is the first to describe Canadian health professional regulatory body perspectives on the complaints and discipline process. More research is needed to better understand the factors that affect discipline outcomes and to ultimately improve complaints and discipline processes.
What Could (Or Should) Be the Regulatory Response to the Wicked Problem of Climate Change?
Authors: Austin Zubin , Háji Aly
Published: August 2024

Sociologists define “wicked problems” as issues confronting humanity that have no clear right answer or perspective. The issue of climate change is a wicked problem of our age—and an issue that few regulators have explicitly addressed within their remit. The polluting effects of health care work itself have recently been highlighted as a call to action within health professions to address climate change issues more forcefully. Perspectives on how and why regulators should—or should not—prioritize climate change in their activities can be difficult to articulate. An approach to this issue that focuses on appropriate and proportionate use of regulatory levers is essential. Processes to allow for greater transparency in discussions, decision making, and strategic plan development are important for regulators to consider. While regulatory bodies vary in their statutory ability or organizational capacity to lead or address climate change directly within their profession, opportunities may exist to partner with other groups to develop evidence-informed options for practitioners.
ANALISIS STRATEGI PEMASARAN PRODUK OLAHAN KAKAO PABRIK MINI CHOKATO
Authors: Nia Rosiana  , Arya Bintama Febby
Published: August 2024

Pabrik Mini Chokato merupakan salah satu industri di Kota Payakumbuh yang telah mampu memproduksi berbagai macam produk lanjutan dari kakao. Pabrik Mini Chokato saat ini produksi pabrik masih dalam skala kecil, sehingga permintaan produk dengan skala besar pabrik belum dapat mengimbanginnya. Penelitian ini bertujuan menganalisis keadaan bauran pemaaran produk olahan kakao, mengidentifikasi faktor-faktor lingkungan internal dan eksternal yang menjadi peluang dan ancaman serta kekuatan dan kelemahan, dan merumuskan alternatif strategi bagi kegiatan pemasaran produk Pabrik Mini Chokato. Metode analisis yang digunakan dalam penelitian ini yaitu, analisis deskriptif dan analisis tiga tahap formulasi strategi. Alat analisis yang digunakan adalah matriks IFE, matriks EFE, matriks IE, matriks SWOT, dan AHP. Hasil analisis matriks IFE Pabrik Mini Chokato memiliki empat kekuatan dan lima kelemahan, dan pada matriks EFE Pabrik Mini chokato memiliki lima peluang dan empat ancaman. Berdasarkan hasil analisis matriks IE, Pabrik Mini Chokato berada pada posisi tumbuh dan bina. Berdasarkan analisis matriks SWOT didapatkan enam alternatif strategi. Prioritas strategi yang dihasilkan dari analisis hirarki proses adalah merencanakan volume produksi yang lebih optimal agar total biaya produksi efisien sehingga meminimalkan resiko dan harga dapat bersaing di pasar.
Analysis Teachers’ Strategies in Teaching Reading Comprehension at Junior High School
Authors: Ningsih Fitri Randia , Kembaren Farida Repelita Waty , Santoso Didik
Published: August 2024

The purpose of this study is to examine the methods English teachers employ to instruct students in reading comprehension as well as how to put such methods into practice. This study used Descriptive qualitative method.The data collected through Observations, interviews, and documentation served as the research tools. Two English teachers who served as informants in this study were the subjects. According to the study's findings, the teacher employed three different methods: scaffolding, question-answer relationships (QARs), and discussion techniques. Students can generate ideas that other students can read by using the scaffolding approach. Using QARs (Question Answer Relationships), teachers can assess how well their pupils comprehend the material presented. Discussion techniques can spark creativity and encourage active collaboration. To analyze the data, the researcher used Miles, Hubermen, and Saldana (2014) technique: data condensation, data display and verification. To establish the trustworthiness of the data, triangulation is used.. After reading the assigned text, the teacher can assess the level of student comprehension of the assignment. Students are then directed to pay closer attention to the text and comprehend its meaning.
A Sociolinguistic Analysis: Raja Ali Haji’s Portrayal of Women's Roles in Malay Society in Syair Sultan Abdul Muluk
Authors: Rosmalina Ida , Zuriyati Zuriyati , Rohman Saifur , Lustyantie Ninuk
Published: August 2024

This research focuses on the analysis Raja Ali Haji’s portrayal of women’s role in Malay Society in Syair Abdul Muluk. This research employs a sociolinguistic approach. In doing this research, the researcher adopted descriptive analysis method in the form of 1818 rhymes, 9 chapters and 189 pages. In Syair Abdul Muluk, women are portrayed as loving creatures but also as someone who can subdue the authorities. The researcher found Raja Ali Hasan has three main views on women role in society these are; as symbol of beauty, symbol of courage dan symbol of resistance. By delving into these themes can offer readers a deeper understanding of societal dynamics and cultural perceptions surrounding gender.
English Writing Assessment in EFL Classrooms at Junior High Schools: What are Teachers’ Perceptions?
Authors: Rahmawati Yeny Richa , Rini Setia
Published: August 2024

This study was conducted to investigate more about how Salatiga junior high school teachers perceived the EFL writing assessment. This study was focused on teachers’ perceptions of objectives for writing assessments and their procedures. This research was conducted using the qualitative research method. The subject for this research is 40 English teachers with above 4 years of experience and over twenty-five years of experience. They were chosen by using a purposive sampling technique. The data were collected by distributing the online questionnaire using Google Forms. The data were analyzed by describing the result of the questionnaire. The research findings showed that the assessment process was carried out to enhance the learning process, according to all the teachers. Most teachers did not agree that writing assessments were just to rank the students. The teachers mostly agreed about the purposes of assessing writing for students, defining the construct when assessing writing, establishing standards to evaluate students' writing, informing students of their progress, giving comments rather than marks, giving diagnostic feedback for students, align feedback with the assessment criteria, use different methods, use alternatives for assessing writing, and use writing tests to obtain a good estimate of students’ writing ability. The study suggests that teachers should evaluate all elements for a good writing assessment, whether in the objective or procedure comprehensively, especially for junior high school students. Teachers' professional development in assessment must be examined to strengthen teachers' abilities to improve their writing assessment practice and ensure that written assessments are effective.