bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure Legend from ZNF668 Functions as a Tumor Suppressor by Regulating p53 Stability and Function in Breast Cancer
Authors: Hu Ruozhen , Peng Guang , Dai Hui , Breuer Eun-Kyoung , Stemke-Hale Katherine , Li Kaiyi , Gonzalez-Angulo Ana M. , Mills Gordon B. , Lin Shiaw-Yih
Published: April 2023

PDF file - 66KB
Supplementary Table 3 from MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-β Signaling Pathway in Human Glioblastoma
Authors: Grzmil Michal , Morin Pier , Lino Maria Maddalena , Merlo Adrian , Frank Stephan , Wang Yuhua , Moncayo Gerald , Hemmings Brian A.
Published: April 2023

Supplementary Table 3 from MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-β Signaling Pathway in Human Glioblastoma
Supplementary Figure 1 from ZNF668 Functions as a Tumor Suppressor by Regulating p53 Stability and Function in Breast Cancer
Authors: Hu Ruozhen , Peng Guang , Dai Hui , Breuer Eun-Kyoung , Stemke-Hale Katherine , Li Kaiyi , Gonzalez-Angulo Ana M. , Mills Gordon B. , Lin Shiaw-Yih
Published: April 2023

PDF file - 1907KB
Supplementary Figures 1-6, Table 1 from Androgen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer Progression
Authors: Wang Qian , Bailey Charles G. , Ng Cynthia , Tiffen Jessamy , Thoeng Annora , Minhas Vineet , Lehman Melanie L. , Hendy Stephen C. , Buchanan Grant , Nelson Colleen C. , Rasko John E.J. , Holst Jeff
Published: April 2023

PDF file - 1.5K
Supplementary Table 2 from Mitochondrial Bcl-2 Family Dynamics Define Therapy Response and Resistance in Neuroblastoma
Authors: Goldsmith Kelly C. , Gross Michelle , Peirce Susan , Luyindula Dema , Liu Xueyuan , Vu Annette , Sliozberg Michael , Guo Rong , Zhao Huaqing , Reynolds C. Patrick , Hogarty Michael D.
Published: April 2023

PDF file - 63K, Fresh frozen neuroblastoma sample characteristics
Supplementary Table 5 from Modulating Microtubule Stability Enhances the Cytotoxic Response of Cancer Cells to Paclitaxel
Authors: Ahmed Ahmed Ashour , Wang Xiaoyan , Lu Zhen , Goldsmith Juliet , Le Xiao-Feng , Grandjean Geoffrey , Bartholomeusz Geoffrey , Broom Bradley , Bast Robert C.
Published: April 2023

XLS file - 493K
Supplementary Figure 2 from Mitochondrial Bcl-2 Family Dynamics Define Therapy Response and Resistance in Neuroblastoma
Authors: Goldsmith Kelly C. , Gross Michelle , Peirce Susan , Luyindula Dema , Liu Xueyuan , Vu Annette , Sliozberg Michael , Guo Rong , Zhao Huaqing , Reynolds C. Patrick , Hogarty Michael D.
Published: April 2023

PDF file - 3.9MB, Evaluations for alternative pro-apoptotic protein interactions with Mcl-1 or Bcl-2
Supplementary Table 4 from Modulating Microtubule Stability Enhances the Cytotoxic Response of Cancer Cells to Paclitaxel
Authors: Ahmed Ahmed Ashour , Wang Xiaoyan , Lu Zhen , Goldsmith Juliet , Le Xiao-Feng , Grandjean Geoffrey , Bartholomeusz Geoffrey , Broom Bradley , Bast Robert C.
Published: April 2023

XLS file - 58K
Supplementary Figure 8 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Authors: Aoki Koji , Kakizaki Fumihiko , Sakashita Hiromi , Manabe Toshiaki , Aoki Masahiro , Taketo Makoto M.
Published: April 2023

Supplementary Figure 8 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Supplementary Figures 1-5, Table 1 from NKX2.2 Suppresses Self-Renewal of Glioma-Initiating Cells
Authors: Muraguchi Teruyuki , Tanaka Shingo , Yamada Daisuke , Tamase Akira , Nakada Mitsutoshi , Nakamura Hideo , Hoshii Takayuki , Ooshio Takako , Tadokoro Yuko , Naka Kazuhito , Ino Yasushi , Todo Tomoki , Kuratsu Jun-ichi , Saya Hideyuki , Hamada Jun-ichiro , Hirao Atsushi
Published: April 2023

Supplementary Figures 1-5, Table 1 from NKX2.2 Suppresses Self-Renewal of Glioma-Initiating Cells
Supplementary Figure 6 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Authors: Aoki Koji , Kakizaki Fumihiko , Sakashita Hiromi , Manabe Toshiaki , Aoki Masahiro , Taketo Makoto M.
Published: April 2023

Supplementary Figure 6 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Supplementary Methods, Table 1, Figures 1-2 from Steroid Receptor Coactivator-1 Upregulates Integrin α5 Expression to Promote Breast Cancer Cell Adhesion and Migration
Authors: Qin Li , Chen Xian , Wu Yelin , Feng Zhen , He Tao , Wang Li , Liao Lan , Xu Jianming
Published: April 2023

Supplementary Methods, Table 1, Figures 1-2 from Steroid Receptor Coactivator-1 Upregulates Integrin α5 Expression to Promote Breast Cancer Cell Adhesion and Migration
Table S2 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Authors: Ruggiero Raúl A. , Bruzzo Juan , Chiarella Paula , di Gianni Pedro , Isturiz Martín A. , Linskens Susana , Speziale Norma , Meiss Roberto P. , Bustuoabad Oscar D. , Pasqualini Christiane D.
Published: April 2023

Table S2 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Supplementary Figure 3 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Authors: Aoki Koji , Kakizaki Fumihiko , Sakashita Hiromi , Manabe Toshiaki , Aoki Masahiro , Taketo Makoto M.
Published: April 2023

Supplementary Figure 3 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Supplementary Figure 2 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Authors: Aoki Koji , Kakizaki Fumihiko , Sakashita Hiromi , Manabe Toshiaki , Aoki Masahiro , Taketo Makoto M.
Published: April 2023

Supplementary Figure 2 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Supplementary Table 2 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Authors: Ruggiero Raúl A. , Bruzzo Juan , Chiarella Paula , di Gianni Pedro , Isturiz Martín A. , Linskens Susana , Speziale Norma , Meiss Roberto P. , Bustuoabad Oscar D. , Pasqualini Christiane D.
Published: April 2023

PDF file - 69K
Supplementary Figure 12 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Authors: Aoki Koji , Kakizaki Fumihiko , Sakashita Hiromi , Manabe Toshiaki , Aoki Masahiro , Taketo Makoto M.
Published: April 2023

Supplementary Figure 12 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Supplementary Figure 10 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Authors: Aoki Koji , Kakizaki Fumihiko , Sakashita Hiromi , Manabe Toshiaki , Aoki Masahiro , Taketo Makoto M.
Published: April 2023

Supplementary Figure 10 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Supplementary Figure 1 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Authors: Aoki Koji , Kakizaki Fumihiko , Sakashita Hiromi , Manabe Toshiaki , Aoki Masahiro , Taketo Makoto M.
Published: April 2023

Supplementary Figure 1 from Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
Supplementary Figure 1 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Authors: Ruggiero Raúl A. , Bruzzo Juan , Chiarella Paula , di Gianni Pedro , Isturiz Martín A. , Linskens Susana , Speziale Norma , Meiss Roberto P. , Bustuoabad Oscar D. , Pasqualini Christiane D.
Published: April 2023

PDF file - 97K
Figure Supplementary 3 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Authors: Ruggiero Raúl A. , Bruzzo Juan , Chiarella Paula , di Gianni Pedro , Isturiz Martín A. , Linskens Susana , Speziale Norma , Meiss Roberto P. , Bustuoabad Oscar D. , Pasqualini Christiane D.
Published: April 2023

Figure Supplementary 3 from Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance
Supplementary Table 1 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Authors: Sakurai Kouhei , Furukawa Chihiro , Haraguchi Takeshi , Inada Ken-ichi , Shiogama Kazuya , Tagawa Takanobu , Fujita Shuji , Ueno Yoshihito , Ogata Aya , Ito Mai , Tsutsumi Yutaka , Iba Hideo
Published: April 2023

Supplementary Table 1 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Supplementary Methods, Figure Legends 1-13 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Authors: Sakurai Kouhei , Furukawa Chihiro , Haraguchi Takeshi , Inada Ken-ichi , Shiogama Kazuya , Tagawa Takanobu , Fujita Shuji , Ueno Yoshihito , Ogata Aya , Ito Mai , Tsutsumi Yutaka , Iba Hideo
Published: April 2023

Supplementary Methods, Figure Legends 1-13 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Supplementary Figure 9 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Authors: Sakurai Kouhei , Furukawa Chihiro , Haraguchi Takeshi , Inada Ken-ichi , Shiogama Kazuya , Tagawa Takanobu , Fujita Shuji , Ueno Yoshihito , Ogata Aya , Ito Mai , Tsutsumi Yutaka , Iba Hideo
Published: April 2023

Supplementary Figure 9 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Supplementary Figure 7 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Authors: Sakurai Kouhei , Furukawa Chihiro , Haraguchi Takeshi , Inada Ken-ichi , Shiogama Kazuya , Tagawa Takanobu , Fujita Shuji , Ueno Yoshihito , Ogata Aya , Ito Mai , Tsutsumi Yutaka , Iba Hideo
Published: April 2023

Supplementary Figure 7 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Supplementary Figure 5 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Authors: Sakurai Kouhei , Furukawa Chihiro , Haraguchi Takeshi , Inada Ken-ichi , Shiogama Kazuya , Tagawa Takanobu , Fujita Shuji , Ueno Yoshihito , Ogata Aya , Ito Mai , Tsutsumi Yutaka , Iba Hideo
Published: April 2023

Supplementary Figure 5 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Supplementary Figure 1 from Absence of Class II–Associated Invariant Chain Peptide on Leukemic Blasts of Patients Promotes Activation of Autologous Leukemia-Reactive CD4+ T Cells
Authors: van Luijn Marvin M. , van den Ancker Willemijn , Chamuleau Martine E.D. , Zevenbergen Adri , Westers Theresia M. , Ossenkoppele Gert J. , van Ham S. Marieke , van de Loosdrecht Arjan A.
Published: April 2023

Supplementary Figure 1 from Absence of Class II–Associated Invariant Chain Peptide on Leukemic Blasts of Patients Promotes Activation of Autologous Leukemia-Reactive CD4+ T Cells
Supplementary Figure 13 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Authors: Sakurai Kouhei , Furukawa Chihiro , Haraguchi Takeshi , Inada Ken-ichi , Shiogama Kazuya , Tagawa Takanobu , Fujita Shuji , Ueno Yoshihito , Ogata Aya , Ito Mai , Tsutsumi Yutaka , Iba Hideo
Published: April 2023

Supplementary Figure 13 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Supplementary Figure 1 from STAT3 Inhibition Is a Therapeutic Strategy for ABC-like Diffuse Large B-Cell Lymphoma
Authors: Scuto Anna , Kujawski Maciej , Kowolik Claudia , Krymskaya Ludmila , Wang Lin , Weiss Lawrence M. , DiGiusto David , Yu Hua , Forman Stephen , Jove Richard
Published: April 2023

Supplementary Figure 1 from STAT3 Inhibition Is a Therapeutic Strategy for ABC-like Diffuse Large B-Cell Lymphoma
Supplementary Figure 11 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Authors: Sakurai Kouhei , Furukawa Chihiro , Haraguchi Takeshi , Inada Ken-ichi , Shiogama Kazuya , Tagawa Takanobu , Fujita Shuji , Ueno Yoshihito , Ogata Aya , Ito Mai , Tsutsumi Yutaka , Iba Hideo
Published: April 2023

Supplementary Figure 11 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Supplementary Tables 1-2, Figure Legends 1-5 from MYB Is Essential for Mammary Tumorigenesis
Authors: Yu Miao Rebecca , Drabsch Yvette , Cross Ryan Stanley , Cheasley Dane , Carpinteri Sandra , Pereira Lloyd , Malaterre Jordane , Gonda Thomas J. , Anderson Robin L. , Ramsay Robert G.
Published: April 2023

PDF file - 168K
Supplementary Figure 10 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Authors: Sakurai Kouhei , Furukawa Chihiro , Haraguchi Takeshi , Inada Ken-ichi , Shiogama Kazuya , Tagawa Takanobu , Fujita Shuji , Ueno Yoshihito , Ogata Aya , Ito Mai , Tsutsumi Yutaka , Iba Hideo
Published: April 2023

Supplementary Figure 10 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Supplementary Tables 10-15 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Authors: Heemers Hannelore V. , Schmidt Lucy J. , Sun Zhifu , Regan Kevin M. , Anderson S. Keith , Duncan Kelly , Wang Dan , Liu Song , Ballman Karla V. , Tindall Donald J.
Published: April 2023

Supplementary Tables 10-15 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Supplementary Table 6 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Authors: Heemers Hannelore V. , Schmidt Lucy J. , Sun Zhifu , Regan Kevin M. , Anderson S. Keith , Duncan Kelly , Wang Dan , Liu Song , Ballman Karla V. , Tindall Donald J.
Published: April 2023

Supplementary Table 6 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Supplementary Table 5 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Authors: Heemers Hannelore V. , Schmidt Lucy J. , Sun Zhifu , Regan Kevin M. , Anderson S. Keith , Duncan Kelly , Wang Dan , Liu Song , Ballman Karla V. , Tindall Donald J.
Published: April 2023

Supplementary Table 5 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Supplementary Figure 4 from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis
Authors: Hu Weiguo , Ge Xiaowen , You Tao , Xu Ting , Zhang Jinyan , Wu Gongxiong , Peng Zhihai , Chorev Michael , Aktas Bertal H. , Halperin Jose A. , Brown Jennifer R. , Qin Xuebin
Published: April 2023

Supplementary Figure 4 from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis
Supplementary Table 4 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Authors: Heemers Hannelore V. , Schmidt Lucy J. , Sun Zhifu , Regan Kevin M. , Anderson S. Keith , Duncan Kelly , Wang Dan , Liu Song , Ballman Karla V. , Tindall Donald J.
Published: April 2023

Supplementary Table 4 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Supplementary Table 2 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Authors: Heemers Hannelore V. , Schmidt Lucy J. , Sun Zhifu , Regan Kevin M. , Anderson S. Keith , Duncan Kelly , Wang Dan , Liu Song , Ballman Karla V. , Tindall Donald J.
Published: April 2023

Supplementary Table 2 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Supplementary Figures 1-4 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Authors: Heemers Hannelore V. , Schmidt Lucy J. , Sun Zhifu , Regan Kevin M. , Anderson S. Keith , Duncan Kelly , Wang Dan , Liu Song , Ballman Karla V. , Tindall Donald J.
Published: April 2023

Supplementary Figures 1-4 from Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer
Supplementary Tables 1-5 from Considerations for the Clinical Application of Chimeric Antigen Receptor T Cells: Observations from a Recombinant DNA Advisory Committee Symposium Held June 15, 2010
Authors: Ertl Hildegund C.J. , Zaia John , Rosenberg Steven A. , June Carl H. , Dotti Gianpietro , Kahn Jeffrey , Cooper Laurence J.N. , Corrigan-Curay Jacqueline , Strome Scott E.
Published: April 2023

Supplementary Tables 1-5 from Considerations for the Clinical Application of Chimeric Antigen Receptor T Cells: Observations from a Recombinant DNA Advisory Committee Symposium Held June 15, 2010
Supplementary Figure 2 from TNF-α Promotes c-REL/ΔNp63α Interaction and TAp73 Dissociation from Key Genes That Mediate Growth Arrest and Apoptosis in Head and Neck Cancer
Authors: Lu Hai , Yang Xinping , Duggal Praveen , Allen Clint T. , Yan Bin , Cohen Jonah , Nottingham Liesl , Romano Rose-Anne , Sinha Satrajit , King Kathryn E. , Weinberg Wendy C. , Chen Zhong , Van Waes Carter
Published: April 2023

PDF file - 2.6MB, ChIP assays of c-REL, deltaNp63alpha and TAp73 binding.
Supplementary Data Legends 1-9 from Human Breast Tumor Cells Induce Self-Tolerance Mechanisms to Avoid NKG2D-Mediated and DNAM-Mediated NK Cell Recognition
Authors: Mamessier Emilie , Sylvain Aude , Bertucci François , Castellano Rémy , Finetti Pascal , Houvenaeghel Gilles , Charaffe-Jaufret Emmanuelle , Birnbaum Daniel , Moretta Alessandro , Olive Daniel
Published: April 2023

PDF file - 113K
Supplementary Data 6 from Human Breast Tumor Cells Induce Self-Tolerance Mechanisms to Avoid NKG2D-Mediated and DNAM-Mediated NK Cell Recognition
Authors: Mamessier Emilie , Sylvain Aude , Bertucci François , Castellano Rémy , Finetti Pascal , Houvenaeghel Gilles , Charaffe-Jaufret Emmanuelle , Birnbaum Daniel , Moretta Alessandro , Olive Daniel
Published: April 2023

PDF file - 63K, Supplemental Data 6: Combined blocking antibodies effect on breast cancer lysis. We measured activated NK-cells mediated cytotoxicity (IL2/IL15 overnight activation), in 4-hours assays, in the presence of blocking antibodies for NKG2D, DNAM-1 and NKp30 or irrelevant IgM alone or in combination. NK-cells cytotoxicity was evaluated with CD107 positivity after target cell exposition. E:T = 2:1. N = 5 donors per cell line.
Supplementary Data 1 from Human Breast Tumor Cells Induce Self-Tolerance Mechanisms to Avoid NKG2D-Mediated and DNAM-Mediated NK Cell Recognition
Authors: Mamessier Emilie , Sylvain Aude , Bertucci François , Castellano Rémy , Finetti Pascal , Houvenaeghel Gilles , Charaffe-Jaufret Emmanuelle , Birnbaum Daniel , Moretta Alessandro , Olive Daniel
Published: April 2023

PDF file - 320K, Supplemental Data 1: Ligands and receptors respectively expressed by tumor and NK-cells. Natural killer (NK) cells are components of the innate immune system that play a central role against tumor cells. They have an innate ability to distinguish normal from "modified" cells, such as cancer cells, through a broad range of activating and inhibitory receptors. These receptors act like little sensors of the malignant self (Moretta et al, 2006); the integration of these opposite signals determines whether an NK-cell will eliminate a potential target or not. NK-cell activating receptors are the natural cytotoxicity receptors (NKp30, NKp46 and NKp44) and NKG2D. They recognize various ligands expressed by transformed cells and/or stressed or activated cells. To date, NKp30 has two described ligands, B7H6 and BAT3. NKG2D can bind MICA, MICB and the members of the ULBP family. The ligand(s) of NKp46 or NKp44 are unknown. The main NK-cell inhibitory receptors are the killer immunoglobulin receptors (KIRs) and NKG2A (Moretta et al., 1995 & 2001), which recognize members of the HLA-I family expressed by normal cells, respectively HLA-A, -B or -C for the KIRs and HLA-E for NKG2A. The signal is fine-tuned by co-activators such as DNAM-1, CD2, NKp80, 2B4, NTBA and co-inhibitors such as the CD85 family, B7-H3 or LAIR. Among co-activator receptors, DNAM-1 binds the heterodimer PVR/Nectin2 receptors, CD2 binds CD58, NTBA binds another NTBA molecule, and 2B4 binds CD48. The co-inhibitory receptors from the CD85 family bind HLA-I molecules, while ligands of the LAIR family and B7H3 are still unknown.
Supplementary Figure 6 from A Role for Bone Morphogenetic Protein-4 in Lymph Node Vascular Remodeling and Primary Tumor Growth
Authors: Farnsworth Rae H. , Karnezis Tara , Shayan Ramin , Matsumoto Masataka , Nowell Cameron J. , Achen Marc G. , Stacker Steven A.
Published: April 2023

PDF file - 147K
Supplementary Figure Legends 1-6, Methods from Pivotal Role of Reduced let-7g Expression in Breast Cancer Invasion and Metastasis
Authors: Qian Pengxu , Zuo Zehua , Wu Zhengsheng , Meng Xianyi , Li Gaopeng , Wu Zhengzhou , Zhang Weijie , Tan Sheng , Pandey Vijay , Yao Yandan , Wang Puyue , Zhao Liqing , Wang Jun , Wu Qiang , Song Erwei , Lobie Peter E. , Yin Zhinan , Zhu Tao
Published: April 2023

PDF file - 214K
Supplementary Methods, Tables 1-5, Figures 1-4 from Classification of Epstein–Barr Virus–Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes
Authors: Matsusaka Keisuke , Kaneda Atsushi , Nagae Genta , Ushiku Tetsuo , Kikuchi Yasuko , Hino Rumi , Uozaki Hiroshi , Seto Yasuyuki , Takada Kenzo , Aburatani Hiroyuki , Fukayama Masashi
Published: April 2023

PDF file - 769K
Supplementary Movie 3 from Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53
Authors: Timpson Paul , McGhee Ewan J. , Morton Jennifer P. , von Kriegsheim Alex , Schwarz Juliane P. , Karim Saadia A. , Doyle Brendan , Quinn Jean A. , Carragher Neil O. , Edward Mike , Olson Michael F. , Frame Margaret C. , Brunton Valerie G. , Sansom Owen J. , Anderson Kurt I.
Published: April 2023

Supplementary Movie 3 from Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53
Supplementary Figure Legend from A Preclinical Mouse Model of Invasive Lobular Breast Cancer Metastasis
Authors: Doornebal Chris W. , Klarenbeek Sjoerd , Braumuller Tanya M. , Klijn Christiaan N. , Ciampricotti Metamia , Hau Cheei-Sing , Hollmann Markus W. , Jonkers Jos , de Visser Karin E.
Published: April 2023

PDF file - 33K
Supplementary Figure 1 from A Preclinical Mouse Model of Invasive Lobular Breast Cancer Metastasis
Authors: Doornebal Chris W. , Klarenbeek Sjoerd , Braumuller Tanya M. , Klijn Christiaan N. , Ciampricotti Metamia , Hau Cheei-Sing , Hollmann Markus W. , Jonkers Jos , de Visser Karin E.
Published: April 2023

PDF file - 1060K, S1. Recipient mice develop pleiomorphic mILCs that are infiltrated by immune cells.
Supplementary Figure S2 from Regulation of FANCD2 by the mTOR Pathway Contributes to the Resistance of Cancer Cells to DNA Double-Strand Breaks
Authors: Shen Changxian , Oswald Duane , Phelps Doris , Cam Hakan , Pelloski Christopher E. , Pang Qishen , Houghton Peter J.
Published: April 2023

Supplementary Figure S2 - PDF file 1693K,FANCD2 is Positively Controlled by CDK4. A, Rh30 cells were transfected with siRNAs of control, CDK4, or CDK6. 72 hr later, total proteins were extracted for detection of FANCD2, CDK4, CDK6, pRb-S780 and Rb by immunoblotting. B, Rh30 cells were treated as in A, total RNA was extracted to detect FANCD2 mRNA by real-time RT-PCR with MYCN as internal control. Relative quantity (Ln) of FANCD2 mRNA was plotted
Supplementary Methods, Figures 1-8, Tables 1-3 from PTP1B Is an Androgen Receptor–Regulated Phosphatase That Promotes the Progression of Prostate Cancer
Authors: Lessard Laurent , Labbé David P. , Deblois Geneviève , Bégin Louis R. , Hardy Serge , Mes-Masson Anne-Marie , Saad Fred , Trotman Lloyd C. , Giguère Vincent , Tremblay Michel L.
Published: April 2023

PDF file - 2.4MB
Supplementary Figure S1 from Regulation of FANCD2 by the mTOR Pathway Contributes to the Resistance of Cancer Cells to DNA Double-Strand Breaks
Authors: Shen Changxian , Oswald Duane , Phelps Doris , Cam Hakan , Pelloski Christopher E. , Pang Qishen , Houghton Peter J.
Published: April 2023

Supplementary Figure S1 - PDF file 2155K, The mTOR Pathway Regulates FANCD2. A, Rh30 cells were exposed to AZD8055 (2 �M) for the times indicated and total proteins were extracted for immunoblotting to detect FANCD2. B, Rh30 cells were transfected with vector, AKT1-Myc plasmid encoding wild type AKT1. 48 hr later, total proteins were extracted for detection of FANCD2, GSK3�, pGSK3�-S9, AKT and pAKT-S473. Myc antibody was used to show the expression of AKT1 wt with Myc tag. C, Rh30 cells were transfected with vector, Myr-AKT1 plasmid encoding constitutively active AKT1. 48 hr later, total proteins were extracted for detection of FANCD2, GSK3�, pGSK3�-S9, AKT and pAKT-S473. D, Rh30 cells were treated with rapamycin (100 ng/mL), AZD8055 (2 �M) or MK2206 (10 �M) for 16 hr. Total proteins were extracted for immunoblotting of FANCD2, S6K1, pS6K1-T389, AKT and pAKT-S473. GAPDH and �-Actin served as loading control
Supplementary Figure Legend from Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner
Authors: Mace Thomas A. , Ameen Zeenath , Collins Amy , Wojcik Sylwia , Mair Markus , Young Gregory S. , Fuchs James R. , Eubank Tim D. , Frankel Wendy L. , Bekaii-Saab Tanios , Bloomston Mark , Lesinski Gregory B.
Published: April 2023

PDF file - 55K
Supplementary Methods, Tables 1-2, Figures 1-3 from MiR-155 Is a Liposarcoma Oncogene That Targets Casein Kinase-1α and Enhances β-Catenin Signaling
Authors: Zhang Pingyu , Bill Katelynn , Liu Juehui , Young Eric , Peng Tingsheng , Bolshakov Svetlana , Hoffman Aviad , Song Yechun , Demicco Elizabeth G. , Terrada Dolores Lopez , Creighton Chad J. , Anderson Matthew L. , Lazar Alexander J. , Calin George G. , Pollock Raphael E. , Lev Dina
Published: April 2023

PDF file - 275K
Supplementary Table 3 from RhoJ Regulates Melanoma Chemoresistance by Suppressing Pathways That Sense DNA Damage
Authors: Ho Hsiang , Aruri Jayavani , Kapadia Rubina , Mehr Hootan , White Michael A. , Ganesan Anand K.
Published: April 2023

XLS file - 16MB, Microarray Dataset. mRNA expression profiles of SK-MEL-28 cells expressing control or RhoJ shRNAs were compared. Significantly upregulated or downregulated genes are indicated (p<.005).
Supplementary Table 6 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: April 2023

XLS file - 27K, Meta-Analysis of 5 human data sets incorporating array expression data
Supplementary Figure 5 from RhoJ Regulates Melanoma Chemoresistance by Suppressing Pathways That Sense DNA Damage
Authors: Ho Hsiang , Aruri Jayavani , Kapadia Rubina , Mehr Hootan , White Michael A. , Ganesan Anand K.
Published: April 2023

PDF file - 184K, RhoJ Uncouples ATR From Chk1. A. RhoJ does not inhibit the DNA damage foci formation.
Supplementary Figure 6 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: April 2023

PDF file - 19K, Decrease response to CAF-derived clcf1 in cntfr-depleted tumor cells
Supplementary Figure 4 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: April 2023

PDF file - 85K, Lung tumor cells and CAFs induce a of CAF-like phenotype in NFs
Supplementary Figure 3 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: April 2023

PDF file - 20K, Survival prognosis of a mouse CAF-secretory gene signature in human NSCLC
Supplementary Figure 2 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: April 2023

PDF file - 56K, A secretory and inflammatory gene signature specific to CAFs
Supplementary Table 1 from Paclitaxel Enhances Therapeutic Efficacy of the F8-IL2 Immunocytokine to EDA-Fibronectin–Positive Metastatic Human Melanoma Xenografts
Authors: Moschetta Michele , Pretto Francesca , Berndt Alexander , Galler Kerstin , Richter Petra , Bassi Andrea , Oliva Paolo , Micotti Edoardo , Valbusa Giovanni , Schwager Kathrin , Kaspar Manuela , Trachsel Eveline , Kosmehl Hartwig , Bani Maria Rosa , Neri Dario , Giavazzi Raffaella
Published: April 2023

PDF file - 73K, Lung colony formation in nude mice given F8-IL2 immunocytokine alone or in combination with paclitaxel
Supplementary Figure 1 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: April 2023

PDF file - 40K, Lung CAFs stimulate lung cancer growth in vivo
Supplementary Materials and Methods from Paclitaxel Enhances Therapeutic Efficacy of the F8-IL2 Immunocytokine to EDA-Fibronectin–Positive Metastatic Human Melanoma Xenografts
Authors: Moschetta Michele , Pretto Francesca , Berndt Alexander , Galler Kerstin , Richter Petra , Bassi Andrea , Oliva Paolo , Micotti Edoardo , Valbusa Giovanni , Schwager Kathrin , Kaspar Manuela , Trachsel Eveline , Kosmehl Hartwig , Bani Maria Rosa , Neri Dario , Giavazzi Raffaella
Published: April 2023

PDF file - 133K
Supplementary Figure Legends 1-8, Table Legends 1-4 from Genomic Profiling of Isolated Circulating Tumor Cells from Metastatic Breast Cancer Patients
Authors: Magbanua Mark Jesus M. , Sosa Eduardo V. , Roy Ritu , Eisenbud Lauren E. , Scott Janet H. , Olshen Adam , Pinkel Dan , Rugo Hope S. , Park John W.
Published: April 2023

PDF file - 85K
Supplementary Figure 3 from PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines
Authors: Peng Weiyi , Liu Chengwen , Xu Chunyu , Lou Yanyan , Chen Jieqing , Yang Yan , Yagita Hideo , Overwijk Willem W. , Lizée Gregory , Radvanyi Laszlo , Hwu Patrick
Published: April 2023

PDF file - 37K, Representative contour plots of F4/80 and Ly6C expression in CXCL10-production CD11b+ cells within tumor tissue from mice treated with ACT and anti-PD-1
Supplementary Figure 2 from PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines
Authors: Peng Weiyi , Liu Chengwen , Xu Chunyu , Lou Yanyan , Chen Jieqing , Yang Yan , Yagita Hideo , Overwijk Willem W. , Lizée Gregory , Radvanyi Laszlo , Hwu Patrick
Published: April 2023

PDF file - 33K, Change in frequency of Treg and MDSCs within tumors from mice receiving ACT in response to PD-1 blockade
Supplementary Figures 6-10 from The Melanoma‐Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion
Authors: Khaitan Divya , Dinger Marcel E. , Mazar Joseph , Crawford Joanna , Smith Martin A. , Mattick John S. , Perera Ranjan J.
Published: April 2023

Supplementary Figures 6-10 from The Melanoma‐Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion
Supplementary Figure Legends 1-5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Authors: Chen Runqiang , Yang Qingkai , Lee Jiing-Dwan
Published: April 2023

PDF file - 66K
Supplementary Figures 16-19 from Antioxidant Enzymes Mediate Survival of Breast Cancer Cells Deprived of Extracellular Matrix
Authors: Davison Calli A. , Durbin Sienna M. , Thau Matthew R. , Zellmer Victoria R. , Chapman Sarah E. , Diener Justin , Wathen Connor , Leevy W. Matthew , Schafer Zachary T.
Published: April 2023

SOD2 deficiency in T47D cells has a negligible impact on cell viability, SOD1 deficiency in T47D cells diminishes ATP levels in ECM-detached cells, Nrf2 deficiency in T47D cells diminishes ATP levels in ECM-detached cells, SOD2 deficiency in ErbB2 positive SKBR3 cells leads to a decrease in ATP levels during ECM-detachment.
Supplementary Figures 12-15 from Antioxidant Enzymes Mediate Survival of Breast Cancer Cells Deprived of Extracellular Matrix
Authors: Davison Calli A. , Durbin Sienna M. , Thau Matthew R. , Zellmer Victoria R. , Chapman Sarah E. , Diener Justin , Wathen Connor , Leevy W. Matthew , Schafer Zachary T.
Published: April 2023

Catalase deficiency in T47D cells does not impact cell proliferation, Catalase deficiency in T47D cells does not impact cell viability, Diminished SOD2 expression in T47D cells has no on glucose uptake, SOD2 deficiency in T47D cells does not impact cell proliferation.
Supplementary Figures 1-4 from Antioxidant Enzymes Mediate Survival of Breast Cancer Cells Deprived of Extracellular Matrix
Authors: Davison Calli A. , Durbin Sienna M. , Thau Matthew R. , Zellmer Victoria R. , Chapman Sarah E. , Diener Justin , Wathen Connor , Leevy W. Matthew , Schafer Zachary T.
Published: April 2023

Antioxidant compound treatment does not affect glucose uptake in detached MCF-10A cells, Antioxidant compound treatment does not alter cell viability in attached E7/Bcl2 cells, Antioxidant compound treatment can be reversible, Catalase expression has no impact on glucose uptake in ECM-detached MCF-10A cells.
Supplementary Figure 3 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Authors: Chen Runqiang , Yang Qingkai , Lee Jiing-Dwan
Published: April 2023

PDF file - 234K
Supplementary Table 1 from Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth
Authors: Kang Moo Rim , Yang Glen , Place Robert F. , Charisse Klaus , Epstein-Barash Hila , Manoharan Muthiah , Li Long-Cheng
Published: April 2023

PDF file - 24K, Oligonucleotide sequences
Supplementary Figure 2 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Authors: Chen Runqiang , Yang Qingkai , Lee Jiing-Dwan
Published: April 2023

PDF file - 240K
Supplementary Figure 1 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Authors: Chen Runqiang , Yang Qingkai , Lee Jiing-Dwan
Published: April 2023

PDF file - 226K
Supplementary Figure 2 from Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases
Authors: Cipponi Arcadi , Mercier Marjorie , Seremet Teofila , Baurain Jean-François , Théate Ivan , van den Oord Joost , Stas Marguerite , Boon Thierry , Coulie Pierre G. , van Baren Nicolas
Published: April 2023

PDF file - 797K, Positive and Negative controls for the immunohistological detection of the indicated antigens in adjacent cryosections of an inflammatory tonsil
Supplementary Figure 1 from Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases
Authors: Cipponi Arcadi , Mercier Marjorie , Seremet Teofila , Baurain Jean-François , Théate Ivan , van den Oord Joost , Stas Marguerite , Boon Thierry , Coulie Pierre G. , van Baren Nicolas
Published: April 2023

PDF file - 418K, Immunohistological detection of the indicated antigens in adjacent cryosections of cutaneous melanoma metastasis T9
Supplementary Figure 4 from eIF4E/4E-BP Ratio Predicts the Efficacy of mTOR Targeted Therapies
Authors: Alain Tommy , Morita Masahiro , Fonseca Bruno D. , Yanagiya Akiko , Siddiqui Nadeem , Bhat Mamatha , Zammit Domenick , Marcus Victoria , Metrakos Peter , Voyer Lucie-Anne , Gandin Valentina , Liu Yi , Topisirovic Ivan , Sonenberg Nahum
Published: April 2023

PDF file - 2.3MB, Figure S4 contains data that show that the eIF4E/4E-BP ratio influences the antiproliferative efficacy of asTORi.
Supplementary Figure 3 from eIF4E/4E-BP Ratio Predicts the Efficacy of mTOR Targeted Therapies
Authors: Alain Tommy , Morita Masahiro , Fonseca Bruno D. , Yanagiya Akiko , Siddiqui Nadeem , Bhat Mamatha , Zammit Domenick , Marcus Victoria , Metrakos Peter , Voyer Lucie-Anne , Gandin Valentina , Liu Yi , Topisirovic Ivan , Sonenberg Nahum
Published: April 2023

PDF file - 2.9MB, Figure S3 contains data that show that cells with elevated eIF4E expression exhibit resistance to asTORi. These data complement the main figures of the manuscript
Supplementary Tables 1-8 from Loss of SNAIL Regulated miR-128-2 on Chromosome 3p22.3 Targets Multiple Stem Cell Factors to Promote Transformation of Mammary Epithelial Cells
Authors: Qian PengXu , Banerjee Arindam , Wu Zheng-Sheng , Zhang Xiao , Wang Hong , Pandey Vijay , Zhang Wei-Jie , Lv Xue-Fei , Tan Sheng , Lobie Peter E. , Zhu Tao
Published: April 2023

PDF file - 226K, TABLE S1: List of miRNAs on human chromosome 3p and the changes of their genome copies determined by genomic real-time PCR; TABLE S2: Clinical significance of the expression of miR-128 in breast cancer patients; TABLE S3: Invariable analysis of clinical outcome according to the expression of miR-128 in breast cancer patients (85 cases); TABLE S4: List of mRNAs predicted to be targeted by miR-128 by all the three programs: MiRanda, Pictar and TargetScan; TABLE S5: qRT-PCR analysis of the effect of forced expression of miR-128 in MDA-MB-231 cells or depleted expression of miR-128 in MCF-10A cells on mRNA levels of several key genes functionally involved in oncogenicity and neoplastic progression; TABLE S6: Sequences of the oligonucleotides for miRNAs, siRNAs, construct-making and ChIP assays; TABLE S7: Sequence of the oligonucleotides for real-time PCR experiments; TABLE S8: List of proteins tested by antibodies and characteristics of the corresponding antibodies used
Supplementary Materials and Methods from Loss of SNAIL Regulated miR-128-2 on Chromosome 3p22.3 Targets Multiple Stem Cell Factors to Promote Transformation of Mammary Epithelial Cells
Authors: Qian PengXu , Banerjee Arindam , Wu Zheng-Sheng , Zhang Xiao , Wang Hong , Pandey Vijay , Zhang Wei-Jie , Lv Xue-Fei , Tan Sheng , Lobie Peter E. , Zhu Tao
Published: April 2023

PDF file - 190K, Includes patient and specimen data, reagent information, miRNA and siRNA transfection, and statistical analysis. Also includes supplementary references
Supplementary Figures 1-6 from Loss of SNAIL Regulated miR-128-2 on Chromosome 3p22.3 Targets Multiple Stem Cell Factors to Promote Transformation of Mammary Epithelial Cells
Authors: Qian PengXu , Banerjee Arindam , Wu Zheng-Sheng , Zhang Xiao , Wang Hong , Pandey Vijay , Zhang Wei-Jie , Lv Xue-Fei , Tan Sheng , Lobie Peter E. , Zhu Tao
Published: April 2023

PDF file - 1291K, FIGURE S1: Representative data of genomic real-time PCR screening for DNA copy numbers of aberrant microRNAs on human chromosome 3p in breast carcinoma and the correlation between expression levels of miR-128 and ARPP21; FIGURE S2: miR-128 depletion confers non-tumorigenic MCF-10A cells with a malignant phenotype in vitro; FIGURE S3: Forced expression of miR-128 alters the morphology and reduces migration and invasion of MCF-7 cells in vitro, whereas miR-128 depletion confers non-tumorigenic HBL-100 cells with a malignant phenotype in vitro; FIGURE S4: miR-128 depletion confers a malignant phenotype on non-tumorigenic MCF-10A cells in vivo and miR-128 represses the CD44+CD24 Neg/Low population in mammary carcinoma cells; FIGURE S5: Interactions between miR-128 and its binding targets; FIGURE S6: Luciferase assay for promoter activity
Supplementary Figure Legends 1-6 from Loss of SNAIL Regulated miR-128-2 on Chromosome 3p22.3 Targets Multiple Stem Cell Factors to Promote Transformation of Mammary Epithelial Cells
Authors: Qian PengXu , Banerjee Arindam , Wu Zheng-Sheng , Zhang Xiao , Wang Hong , Pandey Vijay , Zhang Wei-Jie , Lv Xue-Fei , Tan Sheng , Lobie Peter E. , Zhu Tao
Published: April 2023

PDF file - 205K
Supplementary Tables 1-5 from LIN28 Expression in Malignant Germ Cell Tumors Downregulates let-7 and Increases Oncogene Levels
Authors: Murray Matthew J. , Saini Harpreet K. , Siegler Charlotte A. , Hanning Jennifer E. , Barker Emily M. , van Dongen Stijn , Ward Dawn M. , Raby Katie L. , Groves Ian J. , Scarpini Cinzia G. , Pett Mark R. , Thornton Claire M. , Enright Anton J. , Nicholson James C. , Coleman Nicholas
Published: April 2023

PDF - 62K, Supplementary Table 1: Clinico-pathological data for sample set-3. Supplementary Table 2: Primers used for mRNA qRT-PCR. Supplementary Table 3: Expression of let-7 family microRNAs in pediatric malignant-GCTs. Supplementary Table 4: Let-7 mRNA targets identified in combined microarray analysis of pediatric and adult malignant-GCTs. Supplementary Table 5: The six let-7 mRNA targets selected following microarray and qRT-PCR analysis.
Supplementary Figures 1-12 from LIN28 Expression in Malignant Germ Cell Tumors Downregulates let-7 and Increases Oncogene Levels
Authors: Murray Matthew J. , Saini Harpreet K. , Siegler Charlotte A. , Hanning Jennifer E. , Barker Emily M. , van Dongen Stijn , Ward Dawn M. , Raby Katie L. , Groves Ian J. , Scarpini Cinzia G. , Pett Mark R. , Thornton Claire M. , Enright Anton J. , Nicholson James C. , Coleman Nicholas
Published: April 2023

PDF - 492K, Supplementary Figure 1: Levels of the nine members of the let-7 family in pediatric malignant-GCTs. Supplementary Figure 2: PCR quantification of let-7e, LIN28 and LIN28B in malignant-GCTs.Supplementary Figure 3: Sylamer analysis of up-regulated genes in pediatric and adult malignant-GCTs. Supplementary Figure 4: Correlations between levels of let-7 and mRNA targets. Supplementary Figure 5: PCR quantification of HMGA2 in pediatric malignant-GCTs. Supplementary Figure 6: PCR validation of expression of selected let-7 mRNA targets in pediatric malignant-GCTs. Supplementary Figure 7: Effects of LIN28 depletion in malignant-GCT cells. Supplementary Figure 8: Independent confirmation of specific effects of LIN28 depletion in malignant-GCT cells. Supplementary Figure 9: Effects of let-7e mimic in malignant-GCT cells. Supplementary Figure 10: Relationships between MYCN and C-MYC versus LIN28 and LIN28B in malignant-GCTs. Supplementary Figure 11: MYCN depletion in malignant-GCTs (S11). Supplementary Figure 12: Schematic of the LIN28/let-7 axis in malignant-GCTs.
Supplementary Methods from Epithelial-to-Mesenchymal Transition Induced by TGF-β1 Is Mediated by Blimp-1–Dependent Repression of BMP-5
Authors: Romagnoli Mathilde , Belguise Karine , Yu Ziyang , Wang Xiaobo , Landesman-Bollag Esther , Seldin David C. , Chalbos Dany , Barillé-Nion Sophie , Jézéquel Pascal , Seldin Margaret L. , Sonenshein Gail E.
Published: April 2023

PDF file - 100K
Supplementary Figure 4 from Epithelial-to-Mesenchymal Transition Induced by TGF-β1 Is Mediated by Blimp-1–Dependent Repression of BMP-5
Authors: Romagnoli Mathilde , Belguise Karine , Yu Ziyang , Wang Xiaobo , Landesman-Bollag Esther , Seldin David C. , Chalbos Dany , Barillé-Nion Sophie , Jézéquel Pascal , Seldin Margaret L. , Sonenshein Gail E.
Published: April 2023

PDF file - 222K, Erk1/2 and AP-1 activation is required for the induction of Blimp-1 in breast cancer cells
Supplementary Methods from Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Authors: Kluza Jérome , Corazao-Rozas Paola , Touil Yasmine , Jendoubi Manel , Maire Cyril , Guerreschi Pierre , Jonneaux Aurélie , Ballot Caroline , Balayssac Stéphane , Valable Samuel , Corroyer-Dulmont Aurélien , Bernaudin Myriam , Malet-Martino Myriam , de Lassalle Elisabeth Martin , Maboudou Patrice , Formstecher Pierre , Polakowska Renata , Mortier Laurent , Marchetti Philippe
Published: April 2023

PDF file - 78K
Supplementary Figure 2 from Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Authors: Kluza Jérome , Corazao-Rozas Paola , Touil Yasmine , Jendoubi Manel , Maire Cyril , Guerreschi Pierre , Jonneaux Aurélie , Ballot Caroline , Balayssac Stéphane , Valable Samuel , Corroyer-Dulmont Aurélien , Bernaudin Myriam , Malet-Martino Myriam , de Lassalle Elisabeth Martin , Maboudou Patrice , Formstecher Pierre , Polakowska Renata , Mortier Laurent , Marchetti Philippe
Published: April 2023

PDF file - 511K, Showing the impact of HIF-1α shRNA on mitochondria
Supplementary Figure 6 from A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model
Authors: Gill Bartley J. , Gibbons Don L. , Roudsari Laila C. , Saik Jennifer E. , Rizvi Zain H. , Roybal Jonathon D. , Kurie Jonathan M. , West Jennifer L.
Published: April 2023

PDF file - 35K, q-PCR data for several EMT markers shows that TGFbeta induces changes in expression of EMT-related genes in PEG-encapsulated 344SQ