bluuebunny/crossref_metadata_2025 huggingface dataset:
An ensemble machine learning approach for the prediction of body weight of chickens from body measurement
Authors: Urooj M , Iqbal F , Huma Zil-E-
Published: May 2023

This study aimed to develop an ensemble Machine learning (ML) model based on K-Nearest Neighbor (KNN), Random Forest (RF), Regression Tree (RT) and Support Vector Machine (SVM) for the prediction of body weight (BW) of chickens from their morphometric traits. The data of 100 Ross 308 broiler chickens (50 female and 50 male) from day 1 to 29 were used for predicting the BW of chickens using various body measurements such as body girth, body length, keel length, wing length and shank length. The data were randomly partitioned into training (80%) and testing (20%) datasets and 10-fold cross-validation was employed to check the stability of the model. The predictive performance of the proposed ensemble method was evaluated and compared with individual ML models using evaluation criteria of adjusted coefficient of determination ( ), root mean square error ( ), mean absolute error ( and mean absolute percentage error . The proposed ensemble model outperformed all other ML methods used in the study, having very high predictive accuracy with (0.999, 0.999), (3.222, 5.465), (2.332, 3.913) and (0.941, 2.029) values for training and testing datasets, respectively. The results of the study revealed that the proposed ensemble model may help researchers and practitioners to accurately predict the BW of chickens from body measurements.
Keywords: Body weight, chickens, morphological traits, machine learning, ensemble method
Faktor-faktor yang Memengaruhi Pelaporan Insiden Keselamatan Pasien: Literature Review
Authors: Nurislami Salsabila , Pramesona Bayu Anggileo , Wintoko Risal , Oktarlina Rasmi Zakiah
Published: May 2023

Pelaporan insiden dilakukan untuk menurunkan insiden dan mengevaluasi sistem keselamatan pasien. Laporan akan dikaji dan diberi umpan balik berupa rekomendasi untuk mencegah insiden yang sama terulang kembali. Namun, pada tahun 2022, tingkat pelaporan insiden di Indonesia hanya sebesar 0,22%. Studi ini bertujuan untuk mengetahui faktor apa saja yang memengaruhi pelaporan insiden keselamatan pasien. Dengan mengetahui faktor yang memengaruhi pelaporan insiden keselamatan pasien, institusi terkait dapat membuat kebijakan atau melakukan intervensi untuk meningkatkan pelaporan insiden keselamatan pasien. Tinjauan literatur ini mengunakan beberapa data base, yaitu Pubmed dan Science Direct. Artikel yang digunakan dibatasi pada artikel yang relevan dengan tujuan, artikel tentang pelaporan insiden, artikel penelitian, dan dipublikasikan pada 5 tahun terakhir yaitu 2017-2022 sehingga diperoleh enam artikel. Hasil tinjauan literatur menunjukkan faktor tersering yang berpengaruh terhadap pelaporan insiden yaitu rasa takut, pengetahuan dan pelatihan, umpan balik, serta perbaikan. Faktor-faktor yang berpengaruh terhadap pelaporan insiden keselamatan pasien secara umum berasal dari tiga faktor, yaitu faktor individu, faktor psikologi, dan faktor organisasi.
Studi Kasus Implementasi Terapi Orientasi Realita (TOR) pada Pasien Waham
Authors: Nurin Anggi , Rahmawati Arni Nur
Published: May 2023

Waham merupakan keyakinan yang kuat terhadap sesuatu yang salah yang didasarkan oleh kesimpulan yang salah tentang realita eksternal dan ketidakmampuan untuk membedakan yang nyata dan tidak nyata. Tujuan dilakukan studi kasus ini adalah untuk mengetahui hasil dari implementasi terapi orientasi realita (TOR) pada pasien dengan gangguan proes pikir: waham. Metode yang digunakan adalah studi kasus dengan wawancara, observasi dan studi dokumentasi. Responden yang digunakan dalam studi kasus ini yaitu 1 pasien yang mengalami gangguan proses pikir waham. Hasil studi kasus setelah dilakukan Terapi Orientasi Realita (TOR) menunjukkan bahwa klien mampu berorientasi secara realita. Kegiatan terapi ini sangat efektif dalam mencegah kekambuhan waham pasien, maka disarankan untuk kegiatan terapi orietasi realita (TOR) harus selalu diberikan untuk pasien saat diruangan.
Dampak Mengonsumsi Makanan Kariogenik dan Perilaku Menggosok Gigi terhadap Kesehatan Gigi Anak Usia Sekolah Dasar
Authors: Fuadah Novitasari Tsamrotul , Helena Denni Fransiska , Tazkiyah Ismi
Published: May 2023

Kesehatan gigi dan mulut menjadi suatu masalah kesehatan yang dapat menyebabkan karies gigi pada anak yang memerlukan penanganan segera karena berdampak pada kesehatan gigi dan mulut. Makanan kariogenik adalah makanan manis apabila sering dikonsumsi akan memiliki dampak pada masalah kesehatan gigi. Salah satu cara untuk menjaga kebersihan gigi adalah dengan menggosok gigi dengan baik dan benar. Penelitian ini bertujuan untuk mengetahui hubungan mengonsumsi makanan kariogenik dan perilaku menggosok gigi dengan kesehatan gigi pada anak usia sekolah kelas 2 dan 3 di SDN Sukamulya. Metode penelitian yang digunakan yaitu kuantitatif korelatif dengan pendekatan cross sectional. Populasi sebanyak 109 siswa kelas 2 dan 3 dengan teknik sampling proportionate stratified random sampling sebanyak 86 siswa. Instrumen yang digunakan dalam penelitian ini adalah kuesioner kebiasaan mengonsumsi makanan kariogenik, perilaku menggosok gigi dan kesehatan gigi yang telah lulus uji validitas dan reliabilitasnya. Analisis univariat menggunakan distribusi frekuensi dan analisis bivariat menggunakan chi-square. Hasil penelitian menunjukan hampir sebagian anak memiliki frekuensi sedang dalam mengonsumsi makanan kariogenik, perilaku menggosok gigi cukup baik, sebagian besar kesehatan gigi anak tidak sehat, ada hubungan mengonsumsi makanan kariogenik dengan kesehatan gigi dengan p-value 0,014, dan ada hubungan perilaku menggosok gigi dengan kesehatan gigi dengan p-value 0,000, hal tersebut menyatakan bahwa mengonsumsi makanan kariogenik dan perilaku menggosok gigi merupakan faktor yang mempengaruhi kesehatan gigi.
LOGICAL-FORMING TASKS IN THE DEVELOPMENT OF LOGICAL COMPETENCE OF IT FOREIGN APPLICANTS
Authors:   Kazan (Privolzhsky) Federal University, Fakhertdinova1 D.I. , Zolkin A.L. ,   Povolzhskiy State University of Telecommunications and Informatics
Published: May 2023

The article introduces the definition logical competence of the context of future IT professionals. The difference between existing approaches to the definition of logical competence and logical competences is considered. The importance of logical competence as a main competence on the formation and development of the professional competence of future IT specialists is presented. Difficulties in the process of formation and development of logical competence and ways to solve them are described. An overview of various educational systems of the world aimed at the formation of the logical competence of applicants for IT areas is presented. Also, the difficulties arising in the development of logical competence among foreign applicants of future IT specialists in Russian universities are considered. Despite the seemingly obvious problem of insufficient knowledge of the Russian language for learning, the main difficulty is the difference in programs and methods of learning in different countries. If the Russian educational system in the training of future IT specialists attaches great importance to the fundamental serious mathematical base, then even the best IT education systems in various countries focus on the applied part of disciplines. As you know, in the development of any kind of competencies, the foundation, the basic subjects on the basis of which the competencies are formed, is of paramount importance. The article describes tasks that form and develop the logical competence of applicants for future IT specialists. The proposed definition of logical competence, as well as the ways of its formation and development among applicants for IT areas, can be extended to other technical areas with appropriate refinement and recommended for work with applicants or undergraduate students.
Building a Critical Reflective Practice With High School Language Learners
Authors:   Ritsumeikan Junior and Senior High School, Japan, Flanagan Ann
Published: May 2023

It is rare for language learners, especially young learners, to have the awareness to reflect on their language learning process. This study examines the use of critical reflective writing journals in high school. It follows the journey of two female high school students through three stages of critical reflection: reflection-in- action, reflection-on-action, and reflection-for-action. Students were encouraged to practice consistent reflection outside the classroom, writing twice or three times a week. This case study is aimed at exploring critical reflection, learning beyond the classroom, and motivation. The students applied critical thinking skills to analyze and modify their own learning. Journaling facilitated a greater sense of self-awareness in students, which enabled them to identify their own strengths and improve areas of weakness in language learning. In their view, journals were a valuable resource for studying English. Results support the adoption of critical reflection practices encouraging students to become more involved in their language learning. In becoming more responsible for their learning, students begin to make conscious choices about what they are interested in exploring further while monitoring and evaluating their progress. 言語学習者、特に若い学習者にとって、自分の言語学習過程を振り返る意識を持つことは稀である。本研究は、高等学校における批 判的省察文ジャーナルの使用について検討する。4人の女子高校生が、行動に関する考察、行動のための考察、行動中の考察という3 つの段階を経て、批判的な考察を行う過程を追ったものである。生徒たちは、教室外で、週に2、3回書くという一貫したリフレクション スタイルを実践するよう促された。この研究の目的は、批判的省察、教室を超えた学習、モチベーシを探ることである。生徒たちは、批 判的思考スキルを応用して、自分たちの学習を分析し、修正した。ジャーナルは、生徒の自己認識力を高め、その結果言語学習におけ る自身の強みを認識し、弱点となる分野を改善することを可能にした。参加者は、ジャーナルが英語学習にとって貴重なリソースとな ったという見解を示した。この結果は、生徒が批判的な省察の実践を採用することが、自身の言語学習により深く関与することを可能 にするという仮説を支持するものである。その過程で、学生は自分の学習にもっと責任を持つようになり、自分の進歩を監視し評価し ながら、さらに探究心が刺激されることを意識的に選択するようになるのです。
Enolates ambushed – asymmetric tandem conjugate addition and subsequent enolate trapping with conventional and less traditional electrophiles
Authors: Kisszékelyi Péter , Šebesta Radovan
Published: May 2023

Metal enolates are useful intermediates and building blocks indispensable in many organic synthetic transformations. Chiral metal enolates obtained by asymmetric conjugate additions of organometallic reagents are structurally complex intermediates that can be employed in many transformations. In this review, we describe this burgeoning field that is reaching maturity after more than 25 years of development. The effort of our group to broaden possibilities to engage metal enolates in reactions with new electrophiles is described. The material is divided according to the organometallic reagent employed in the conjugate addition step, and thus to the particular metal enolate formed. Short information on applications in total synthesis is also given.
Nursing care in the process of transition to mothehood in obese women
Authors:   Universidad de Córdoba-Universidad de Antioquia, Bula Romero Javier Alonso , Arzuaga Salazar María Angélica , Giraldo Mora Clara Victoria
Published: May 2023

Review question / Objective: To review and synthesize qualitative evidence related to the Nursing care in the process of transition to maternity in obese women. Condition being studied: The transition to motherhood is one of the most important in the life of many women, however, in women with obesity, it represents a critical, confusing moment and often contradictory. Nursing care should help this process occur in a positive way; However, the literature does not indicate a concept that accounts for the care of Nursing in the process of transition to maternity in women with obesity.
What Processes of Change Do Mindfulness Apps Impact? A Systematic Review
Authors:   Beth Israel Deaconess Medical Center / Harvard Medical School, Macrynikola Natalia , Mir Zareen , Gopal Tishmattie , Rodriguez Erica , Li Sunnie , Cox Milann , Yeh Gloria , Torous John
Published: May 2023

Review question / Objective: To summarize the published evidence on the impact of mindfulness apps on the psychological processes known to mediate transdiagnostic symptom reduction after mindfulness practice. This review focuses on randomized controlled trials (RCTs) that evaluated commercially available mindfulness-based mobile apps in adult (>18 years old) populations with validated and reliable outcome measures. Condition being studied: Mechanisms of mindfulness practice, or the processes of change that explain the downstream effects of mindfulness practice on such disorders as depression and anxiety. This review focused on a list of theoretically and empirically supported mechanisms.
Exploring whether social media misinformation contributes to COVID-19 vaccine hesitancy in the pregnant population: A systematic review
Authors:   McMaster University, Malik Mahnoor , Bauer-Maison Natasha , Guarna Giuliana , Sharma Sapna , D'Souza Rohan
Published: May 2023

Review question / Objective: The objectives of this review were to 1) determine examples of misinformation on social media regarding COVID-19 vaccination and pregnancy, 2) reasons for the spread of misinformation, and 3) summarise suggested solutions from the papers we analysed. Condition being studied: COVID-19 vaccination hesitancy in pregnant individuals. Eligibility criteria: The inclusion criteria were original research studies that discussed misinformation on social media related to the COVID-19 vaccine related to pregnancy. The exclusion criteria were studies not published in English or where there was insufficient information to include (such as where a full-text was not available).
En crisis social los aspectos que limitan el crecimiento de las Microempresas del sector de hoteles en la Localidad de Tambobamba 2023
Authors: Huamaní Arone José , Félix Guerrero Zacarías , Vargas Ortega Heiner Rhaner
Published: May 2023

Como objetivo de investigación es identificar en el contexto de crisis social los aspectos que limitan el crecimiento de las microempresas del sector de hoteles en la localidad de Tambobamba 2023. La metodología desarrollada es tipo básica, nivel descriptivo, diseño no experimental transversal, muestra de 28 empresas hoteleras, a una técnica de encuesta y el instrumento es cuestionario, los resultados alcanzados es que el 64.3% de las empresas trabajan con sus recursos propios lo que es el autofinanciamiento, donde llegó concluir que la gran parte de establecimientos microempresas hoteleras trabajan con financiamiento interno, como también no cuentan con el apoyo financiero del gobierno, pocos acceden al crédito a caja Cusco, mientras trabajan con los recursos propios, es así que pocas de las empresas accedes o financiamiento externo, algunas se están adecuado al comercio electrónico, utilizando la venta online a través de los canales de plataformas de marketing digital y lo que es atención personalizado.
La Biología Molecular del envejecimiento
Authors: Ramírez Ramírez Gloria Elizabeth
Published: May 2023

Este artículo se enfoca en explorar los procesos moleculares subyacentes al envejecimiento y cómo estos procesos pueden contribuir al desarrollo de enfermedades crónicas y degenerativas. La metodología utilizada fue una revisión sistemática de la literatura, con un enfoque cuantitativo y un diseño observacional transversal. La población de estudio fue organismos multicelulares y se seleccionaron estudios publicados en revistas científicas indexadas. Los principales hallazgos incluyen la acumulación de daño en el ADN y la activación de la senescencia celular como factores importantes en el envejecimiento celular, y la epigenética también se ha implicado en el envejecimiento. Estos resultados tienen implicaciones importantes para el desarrollo de tratamientos y estrategias preventivas para enfermedades relacionadas con la edad.
Evaluación clínica y manejo diagnóstico de la Leishmaniasis Cutánea. Presentación de caso y revisión de la literatura
Authors: Domínguez Hermenejildo Michelle , Maldonado Gómez Michael , Pinchevsky Girón Cinthya , Torres Solís Tatiana , Bravo Rios Santiago , Cobos Paladines Vanessa
Published: May 2023

La leishmaniasis es una enfermedad causada por un protozoo flagelado perteneciente al género Leishmania. Tiene distribución mundial, aunque la mayoría de los casos se agrupan en América del Sur, la cuenca mediterránea y algunas zonas de Asia y África. En América Latina la leishmaniasis cutánea se ha ido presentando en mayor cantidad, es una enfermedad desentendida. El objetivo principal de este artículo es indagar y actualizar los conocimientos sobre Leishmaniasis Cutánea, prevalencia, factores de riesgo y diagnóstico en Latinoamérica. Se trata de un tipo de investigación de revisión documental y descriptiva junto a la presentación de un caso de paciente diagnosticado con leishmaniasis cutánea. Para la búsqueda bibliográfica se recabó información de aquellos artículos, estudios de casos, o revisiones que hayan sido publicados en idioma español e inglés y ser encontrados en base de datos como Scielo, Redalyc, PubMed y Google Académico. Los resultados demostraron que la leishmaniasis cutánea es endémica en los países de Latinoamérica y que pese a esto no es muy tomada en cuenta al momento de tomar decisiones que puedan contrarrestar la enfermedad. Sus factores de riesgo se deben a las condiciones socioeconómicas en los que viven muchos habitantes, puesto a que no tienen los recursos económicos necesarios para adecuar sus hogares y puedan ser más protegidos por los flebótomos. El obtener un diagnóstico definitivo de la leishmaniasis cutánea usan técnicas de laboratorio como el frotis, la prueba de Montenegro y el cultivo. Se concluye que la leishmaniasis cutánea afecta especialmente a las poblaciones más pobres ya que se asocia por la malnutrición o malas condiciones de vivienda. Es indispensable que el personal de salud debe ser capacitado para reconocer la zoonosis en su primera etapa, tratarlos oportunamente y evitar errores diagnósticos. Así como iniciar el tratamiento acorde con los parámetros dispuestos, esperando que la evolución de los pacientes sea favorable
El empoderamiento en los docentes de la Licenciatura en Administración del TECNM Campus Tecnológico de Estudios Superiores de Jilotepec
Authors: Hernández Narváez Ana Luisa , Pérez Mireles Emilio , Garrido González Erika , Brito Monroy Jorge
Published: May 2023

El presente artículo fue elaborado por docentes del Tecnológico Nacional de México TECNM Campus Tecnológico de Estudios Superiores de Jilotepec y tiene como objetivo identificar el grado de empoderamiento en los docentes de la licenciatura en administración del TECNM Campus Tecnológico de Estudios Superiores de Jilotepec, para conocer su influencia en la satisfacción laboral; para ello se diseñó un instrumento de recolección de información denominado escala tipo Likert con 20 afirmaciones que hacen referencia al empoderamiento, autonomía y satisfacción laboral, se emplea una metodología mediante un enfoque cualitativo, descriptivo, no experimental, transversal, no probabilístico y por conveniencia; los sujetos de estudio fueron los docentes de dicha carrera, donde se concluye que existe un alto grado de empoderamiento en los docentes teniendo bien definidas cuáles son sus responsabilidades y tareas; el 87% de los docentes se sienten satisfechos, motivados y con autonomía con el trabajo que realizan; así mismo, se tienen áreas de oportunidad en cuanto al reconocimiento personal, capacitación adecuada y el proceso para ocupar plazas vacantes.
Perbandingan algoritma k-nearst neighbor dan naïve bayes pada aplikasi shopee
Authors: A. Oktian Permana  , Sudin Saepudin
Published: May 2023

E-commerce merupakan aplikasi yang digunakan untuk melakukan segala aktivitas jual-beli secara online beberapa masalah transaksi jual-beli online terutama pada shopee terkadang banyak kendala. Ulasan dari pengguna sering digunakan sebagai alat yang efektif dan efisien untuk mencari informasi tentang suatu produk atau layanan. Pengguna internet sering melihat ulasan suatu produk sebelum menggunakannya karena ulasan dari pengguna lain dapat memberikan informasi terkini. Pada penelitian ini penulis menggunakan dua (2) jenis metode algoritma yakni K-Nearst Neighbor dan Naive Bayes Classifier. Penulis menggunakan dua (2) metode untuk mengetahui tingkat akurasi terbaik yang di hasilkan. Penulis menggunakan algoritma K-Nearst Neighbor karena pada penelitian sebelumnya terdapat hasil yang bagus. Juga menggunakan algoritma Naïve Bayes Classifier karena metode ini merupakan metode yang popular dan lebih sering digunakan.algoritma K-Nearst Neighbor pada aplikasi shopee menunjukkan bahwa tingkat akurasi 55.00% dimana jumlah data untuk sentimen negatif sebanyak 100 ulasan, dan sentimen positif sebanyak 100 ulasan dari data testing yang digunakan sebanyak 200 data atau 20% dalam metode K-Nearst Neighbor. Lalu tingkat akurasi mencapai 80,00% dimana jumlah data untuk sentimen negatif sebanyak 99 ulasan dan sentimen positif sebanyak 101 ulasan dari data testing yang digunakan sebanyak 200 atau 20% dengan metode Naïve Bayes Classifier. Dalam penelitian ini, dapat diketahui bahwa metode Naïve Bayes Classifier adalah metode yang tingkat akurasinya lebih tinggi dibandingkan K-Nearst Neighbor dengan tingkat akurasi sebesar 80,00%.
UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN PEPAYA (Carica papaya L.) PADA MENCIT PUTIH JANTAN (Mus musculus L.)
Authors: Ardhiasari Astatin , Vivin Nopiyanti  , Jena Hayu Widyasti
Published: May 2023

Depresi merupakan suatu gangguan emosional dalam waktu jangka yang panjang yang disebabkan turunnya kadar neurotransmiter didalam otak. Daun pepaya (Carica papaya L.) memiliki kandungan senyawa alkaloid, flavonoid, saponin, dan tanin yang digunakan sebagai antidepresan. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antidepresan dan dosis yang efektif pada ekstrak etanol daun pepaya (Carica papaya L.). Pada penelitian ini menggunakan ekstrak etanol daun pepaya dengan uji antidepresan dan metode forced swimming test dengan mengamati immobility time pada mencit. Sebanyak 25 ekor mencit jantan dibagi kedalam 5 kelompok uji. Kelompok pertama diberi CMC Na 0,5% sebagai kontrol negatif. Kelompok kedua diberi amitriptilin dengan dosis 0,065 mg/20 g BB mencit sebagai kontrol positif. Kelompok ekstrak daun pepaya (Carica papaya L.) dibuat dengan menggunakan metode maserasi dan pelarut etanol 96% dengan 3 variasi dosis (150 mg/kgBB; 250 mg/kgBB; dan 350 mg/kgBB). Masing masing kelompok uji sebelumnya telah diinduksi depresi selama 7 hari dengan cara direnangkan. Setelah itu mencit diberi perlakuan sampai hari ke-14. Pengamatan Immobility time pada mencit diamati pada hari ke 1, 7, dan 14. Hasil dari penelitian ini menunjukkan bahwa ekstrak daun pepaya mempunyai aktivitas sebagai antidepresan yang dilihat dari immobility time dengan metode forced swimming test. Dosis yang paling efektif untuk menurunkan waktu imobilitas secara signifikan pada mencit adalah dosis 350 mg/kgBB.
Kata kunci : Antidepresan; ekstrak daun pepaya; immobility time; forced swimming test
EFEKTIVITAS PROGRAM KARTU PRAKERJA DI MASA PANDEMI (STUDI DINAS PERINDUSTRIAN DAN TENAGA KERJA KOTA SURABAYA)
Authors: ZURAIDAH ZURAIDAH , ENDARTI ESA WAHYU
Published: May 2023

Pada masa pandemi Covid – 19, sektor ketenagakerjaan mencatat semakin tingginya angka lonjakan tingkat pengangguran. Dengan adanya hal tersebut mendorong Pemerintah menciptakan sebuah program baru yaitu program kartu prakerja yang dianggap sebagai program unggulan untuk meningkatkan kompetensi kerja, membantu meredam jumlah tingkat pengangguran yang semakin meningkat serta program yang digunakan sekaligus untuk perlindungan sosial bagi masyarakat yang belum mendapatkan bantuan sosial lainnya. Tujuan dari penelitian ini adalah untuk menganalisis terkait dengan tingkat efektivitas program kartu prakerja yang ada di Kota Surabaya melalui proses wawancara dan pencarian data dengan pihak Dinas Perindustrian dan Tenaga Kerja Kota Surabaya selaku pemberi fasilitas pelayanan terkait program kartu prakerja. Hal itu disebabkan karena pada masa pandemi Covid – 19, angka pengangguran yang ada di Kota Surabaya mengalami peningkatan secara drastis dari tahun - tahun sebelumnya. Penelitian ini menggunakan jenis penelitian deskriptif kualitatif. Teknik pengumpulan data dilakukan dengan menggunakan metode wawancara dan dokumentasi. Tehnik analisis data yang digunakan menggunakan model analisis data interaktif dari Miles dan Huberman. Dalam Program kartu prakerja di masa pandemi di Kota Surabaya ini dapat dikatakan Relatif Efektif karena dalam program ini masih ada beberapa kekurangan atau hambatan yang menjadikan program ini belum sepenuhnya optimal dan masih perlu untuk diperbaiki lagi. Hasil yang ditunjukkan selama pengimplementasian Program Kartu Prakerja di Kota Surabaya ini sudah baik dan sangat signifikan keberhasilannya dalam mengurangi angka tingkat pengangguran bagi masyarakat yang terdampak pandemi Covid-19. Hal tersebut terbukti dari hasil survey Manajemen Pelaksana yang sudah divalidasi oleh Badan Pusat Statistik dan Sakernas pada Agustus 2020.
Laparoscopic splenectomy for isolated sarcoidosis of the spleen. Clinical case
Authors: Galliamov E. A. , Shalygin A. B. , Kikhlyarov P. V. , Gorbacheva I. V. , Gadlevsky G. S. , Gololobov G. Yu. , Ovchinnikova U. R. , Burmistrov A. I. , Chicherina M. A.
Published: May 2023

The clinical case presented in this article illustrates one of the rare manifestations of systemic sarcoidosis — an isolated sarcoidosis lesion of the spleen. In a 36-year-old patient, based on anamnestic information and preoperative instrumental examination, a nonspecific granulomatous lesion of the spleen was suspected. Surgical intervention was performed in the scope of laparoscopic splenectomy with subsequent morphological verification of the diagnosis. According to the pathohistological examination, the diagnosis of sarcoidosis of the spleen was established. The patient was discharged in a satisfactory condition on the 6th day.
Surgical treatment of Crohn's disease: the risk of complications
Authors: Danilov M. A. , Leontyev A. V. , Baichorov A. B. , Abdulatipova Z. M. , Saakyan G. G. , Demidova A. A.
Published: May 2023

Aim: assessment of the impact of biological therapy on risk factors for postoperative complications. Materials and methods: the study included 116 patients operated on for Crohn's disease. The mean age of the patients was 38.2 years, among them 65 men (56 %) and 51 women (44 %). The influence of various factors on complications in the postoperative period was analyzed using the IBM-SPSS software for Mac version 22.0 and Microsoft Excel 1997-2003. Results: 32.7 % of the patients received biological therapy, and postoperative complications developed in 31 % of the operated patients. There was no association between receiving biological therapy and the risk of postoperative complications. The risk factor was the formation of a stoma and surgery for emergency indications. Conclusion: an important task before surgical treatment for Crohn's disease is a thorough preoperative preparation and assessment of all risk factors for complications of surgical intervention by a multidisciplinary team.
Radiomics and artificial intelligence in the differential diagnosis of tumor and non-tumor diseases of the pancreas. Review
Authors: Paramzin F. N. , Kakotkin V. V. , Burkin D. A. , Agapov M. A.
Published: May 2023

This work provides a comprehensive overview of the recent advancements in the field of radiomic diagnostics and artificial intelligence (AI) in the diagnosis of pancreatic diseases. The integration of radiochemical analysis and AI has allowed for more accurate and precise diagnoses of pancreatic diseases, including pancreatic cancer. The review highlights the different stages of radiomic analysis, such as data collection, preprocessing, tumour segmentation, data detection and extraction, modeling, statistical processing, and data validation, which are essential for the accurate diagnosis of pancreatic diseases. Furthermore, the review evaluates the possibilities of using AI and artificial neural networks in surgical and oncological pancreatology. The features and advantages of using radiochemical analysis and AI in the diagnosis and prognosis of pancreatic cancer are also described. These advancements have the potential to improve patient outcomes, as early and accurate diagnosis can lead to earlier treatment and better chances of recovery. However, the limitations associated with the use of radiometry and AI in pancreatology are also noted, such as the lack of standardization and the potential for false positives or false negatives. Nevertheless, this work highlights the potential benefits of incorporating radiochemical analysis and AI in the diagnosis and treatment of pancreatic diseases, which can ultimately lead to better patient care and outcomes.
Arthrofibrosis of the elbow joint: mechanisms and factors of development
Authors: Egiazaryan K. A. , Lazishvili G. D. , Ratyev A. P. , Badriev D. A. , Zhavoronkov E. A. , Lidyaev A. A.
Published: May 2023

Degenerative diseases that involve excessive formation of fibrous tissue are complex and common problems. These diseases cause pronounced and often irreversible changes, resulting in the dysfunction of the affected organ. Osteoarthritis, osteoarthritis, and arthrofibrosis are pathological conditions characterized by chronic inflammation and excessive proliferation of connective tissue. The elbow joint, being the most mobile and anatomically stable joint in humans, is often affected by arthrofibrosis, resulting in significant functional impairment and reduced quality of life for patients. This problem has significant social relevance. Understanding the mechanisms that lead to arthrofibrosis can help determine the most effective therapeutic interventions, the optimal timing for treatment and rehabilitation, and the use of preventive measures to reduce the risk of relapse.
COVID-19 during the Third Semester of Pregnancy: Maternal Characteristic, Possibility of Intrauterine Transmission and Neonatal Outcome in Aceh, Indonesia
Authors: Yeni Cut Meurah , Hayati Zinatul , Ali Sarjani M. , Hasanuddin Hasanuddin , Rusnaidi Rusnaidi , Maharani Cut Rika
Published: May 2023

Background: Pregnant women are vulnerable against COVID-19 infection due to physiological and immunological changes. COVID-19 in pregnancy affects fetal well-being with a potential for vertical infection.
Materials and Method: This study aims to determine the incidence of vertical infection and anti-SARS-CoV-2 antibodies in infants born to mothers with positive COVID-19 infection. Amniotic fluid, swabs of the newborn's nasopharynx and oropharynx, and swabs of the placenta were examined using RT-PCR for SARS-CoV-2. Serological examination was performed by Electro-Chemiluminescence Immunoassay (ECLIA) on infant’s blood.
Result: Four of 33 pregnant women gave birth to infants positive SARS-CoV-2 infection. RT-PCR examination of all amniotic fluid and placental swabs were negative for SARS-CoV-2. Four of 33 infants (12.1%) showed negative PCR results but positive SARS-CoV-2 antibodies, another 4 newborns (12.1%) showed positive PCR results, but no SARS-CoV-2 antibodies detected. The remaining 25 babies (75.8%) showed both negative PCR and serologic results. Conclusion: No evidence of vertical transmission found in this study.
Cinnamomum burmannii Bl. Bark Ameliorate Lipid Profile and Platelet Aggregation in Dyslipidemia Mice through Antioxidant Activity
Authors: Sandhiutami Ni Made Dwi , Dewi Rika Sari , Suryani Lilis , Hendra Adriani , Christopher Kevin
Published: May 2023

BACKGROUND: Cinnamomum burmannii Bl. has a higher coumarin, flavonoids, saponins, and alkaloids.
AIM: We investigated the antioxidant, anti-platelet aggregation, and anti-dyslipidemia activity of cinnamon bark extract (CBE) in dyslipidemia mice.
METHODS: Mice were divided randomly into six groups (n = 5) that consist of normal control, negative control, positive control (atorvastatin), and test groups of CBE at doses 300, 400, and 500 mg/kg BW. All groups except normal control were given dyslipidemic-induced feed for 14 days. After that, the induction of dyslipidemia was stopped, then continued with suspension of atorvastatin (positive control) and the test group was given CBE for 7 days. Then, it was measured malondialdehyde (MDA), superoxide dismutase (SOD), bleeding time, coagulation time, total cholesterol, triglyceride, low density lipoprotein (LDL), and high-density lipoprotein (HDL).
RESULTS: The CBE has antioxidant activity by decreased MDA concentrations and increased SOD activity in dose group 300; 400; and 500 mg/kg BW compared to negative control. The anti-platelet aggregation of CBE showed that the effects of prolong bleeding time and coagulation time and improve the decreased plasma absorbance after the addition of ADP. There was a decrease in total cholesterol for the three dose groups, respectively, 20.14%, 24.42%, and 35.76%. Triglyceride levels decreased by 4.09%, 8.74%, and 12.5%. LDL levels decreased by 38.17%, 53.8%, and 67.96%. HDL levels increased by 27.29%, 67.8%, and 72.64%.
CONCLUSION: CBE has antioxidant, anti-platelet aggregation and anti-dyslipidemia activity, and potential to prevent cardiovascular disease.
Relationship of Vaccination History and Pregnancy Health Protocol Compliance with Positive Antigen Test Result at Community Health Center in Medan, Indonesia
Authors: Lumbanraja Sarma Nursani , Hayati Reni , Sukatendel Khairani , Marpaung Johny , Rusda Muhammad , Ardiansyah Edy
Published: May 2023

BACKGROUND: A comprehensive screening at delivery revealed that roughly 14% of pregnant women who tested positive for COVID-19 did not exhibit any symptoms. The SARS-CoV-2 antigen swab test is frequently utilized as a diagnostic technique. Inadequate implementation of health protocol compliance can enhance the vulnerability of a community to the COVID-19 virus, according to previous findings. This suggests that these health protocol compliance and the vaccination program are important for preventing and controlling the spread of the virus.

AIM: This study aims to determine the relationship of vaccination history and health protocol compliance with positive antigen swab results among pregnant women at the Community Health Center in Medan.

METHODS: This is a cross-sectional and observational study that was conducted in February 2022 at the Community Health Center in Medan, North Sumatra, Indonesia. Two hundred pregnant women who met the inclusion and exclusion criteria make up the sample population. Antigen sampling for SARS-CoV-2 was performed in the Pramita laboratory. Following the collection and processing of sample and antigen swab data, IBM SPSS® version was utilized to conduct statistical analysis.

RESULTS: The result showed that four of the pregnant women were infected with COVID-19, and they accounted for 2% of the sample population. The health protocol carried out by pregnant women was not significantly related to the swab results. Therefore, vaccination history had no significant association with COVID-19 symptoms, but people who received vaccines had more negative swab test results compared to those who did not, where three out of four positive samples were unvaccinated.

CONCLUSION: Based on the results, only 2% of pregnant women were infected with COVID-19 at the Community Health Centre in Medan, because this study was carried out when COVID-19 cases had decreased. The statistical analysis results showed that the history of vaccination was not significantly related to SARS-CoV-2 antigen swab results. However, there was a clinical tendency that vaccines can reduce the number of positive cases, where three out of four positive samples were not vaccinated.
The Relation between Mean Platelets Volume and Obesity among patients in the Primary Health-care Centers at National Guard in Jeddah, Saudi Arabia
Authors: Alzahrani Abduallah , Alshehri Yasmeen , Alageel Nourah , Bakraa Roaa , Rawas Renad , Alwagdani Raghed
Published: May 2023

BACKGROUND: Obesity is excess and fat accumulation that lead to negative effects on health. Many studies found an association between obesity and MPV. MPV is a determinant of platelet function, since platelet size has been proven to reflect platelet activity, which is an useful predictive biomarker for a variety of diseases. This is the second study in which MPV was evaluated in obese patients in KSA.

AIM: The aim of study is to evaluate the relation between MPV and obese patients without metabolic risk factors at NGHA Jeddah, KSA. Secondary objectives are to compare between genders and to evaluate the association between total platelets count and obesity.

METHODS: This was a cross-sectional study, A. Inclusion criteria: For the first group, any patient with BMI ≥ than 30 kg/m2 aged 18 years or more. Second group, non-obese aged 18 years or more. Exclusion criteria: Metabolic risk.

RESULTS: There were 279 participated in this study. Most of the participants 214 (72.1%) were females, and 83 (27.9%) were males (Table 1). The mean age was 33.39 ± 10.19. There were 148 (49.8%) participants with normal BMI level, and 149 (50.2%) considered as obese. For MPV classification, 287 (96.6%) were normal, and 10 (3.4%) were high. In this case–control study, we found no significant evidence relating the association between MPV and obesity.

CONCLUSION: In this study, we found no significant difference between MPV and platelet count between them. However, there was a significant positive week correlation between BMI and age with p = 0.0001.
Relationship Between Pulmonary Vascular Dilatation and Clinical Symptoms on Chest Computed Tomography in Patients with Confirmed COVID-19
Authors: Asriyani Sri , Latief Nikmatia , Zainuddin Andi Alfian , Amir Muzakkir , Murtala Bachtiar , Toreh Hendra
Published: May 2023

Introduction: Chest computed tomography (CT) is important in establishing a diagnosis, including detecting pulmonary vascular dilatation as a radiological feature of COVID-19, and consequently in providing comprehensive treatment. This study aimed to analyze the relationship between pulmonary vascular dilatation and clinical symptoms on chest CT in patients with confirmed COVID-19.
Methods: This retrospective cross-sectional study was conducted at the Radiology Department of Dr. Wahidin Sudirohusodo Hospital and Hasanuddin University Hospital, Makassar, Indonesia, from July to September 2021 in a total of 231 patients with confirmed COVID-19. The chi-squared correlation test was used to analyze the data, with p-values of <0.05 considered significant.
Results: Pulmonary vascular dilatation was observed in 31 (37.8%) of the 82 patients with confirmed COVID-19 with mild-to-moderate clinical symptoms and in 51 (69.8%) of the 73 patients with confirmed COVID-19 with severe-to-critical clinical symptoms. The incidence of pulmonary vascular dilatation increased in the patients with confirmed COVID-19 with severe-to-critical clinical symptoms. The chief complaints of most patients were cough, shortness of breath, and fever. In the patients with mild-to-moderate clinical symptoms, the most common chief complaint was cough (n=53; 64.63%), while in those with severe-to-critical clinical symptoms, the most common chief complaint was shortness of breath (n=60; 82.19%).
Conclusions: Based on chest CT findings, pulmonary vascular dilatation is related to clinical symptoms in patients with confirmed COVID-19.
Excellent Closure of Postauricular Defect Using Type-1 Keystone Perforator Island Flap: An Alternative Facial Reconstruction Technique
Authors: Eryanda Farah , Anwar Anis Irawan , Djawad Khairuddin , Nurdin Airin , Wahab Siswanto , Idrus Idrianti
Published: May 2023

The use of local flaps is a common and effective method for reconstructing various post-surgical defects. Some advantages of local flaps compared to other methods such as skin grafts are the relatively high success rate and lower complication rates such as infections and wound dehiscence. There are various methods of flaps available and choosing the proper method is based on various factors such as the size of the defect, anatomical location of the defect, and operator capabilities. Therefore, an effective but simple local flap method with a high success rate is needed especially when dealing with defects located on prominent cosmetic areas such as the face. We report the successful use of the keystone perforator island flap for closure of a facial defect caused by basal cell carcinoma removal in a 76-year-old female patient. Although not commonly used for facial reconstruction, this paper reports successful use of this relatively simple and effective method prompting the potential for increased usage in treating small-moderate sized defects on the face.
The Effectiveness and Safety of Supine Percutaneous Nephrolithotomy in Single-Center Tertiary Hospital
Authors: Ibrahim Muhammad Kemal Thariq , Daniswara Nanda , Santosa Ardy , Soedarso Mohamad Adi , Nugroho Eriawan Agung , Wibisono Dimas Sindhu , Addin Sofyan Rais
Published: May 2023

ABSTRACT
Introduction : Percutaneous nephrolithotomy (PCNL) is currently recommended for patients with kidney stones larger than 20 mm. PCNL was firstly introduced in supine position in 1986. It demonstrated advantages in terms of ergonomics and shown to be less risky compared to prone position. However, there is still lack of evidence for the effectiveness nor safety of supine PCNL in Indonesia.
Objective: To analyze the effectiveness and safety of supine PCNL in single centre tertiary hospital.
Materials and Methods : 506 patients undergone supine PCNL from January 2017 to December 2021 in Dr. Kariadi general hospital were invited as sample. The retrospective data was collected from the electronic medical record system and then tabulated and analyzed using SPSS system.
Results : Out of 506 samples, the mean age was 53.19±11.82 years old with the youngest being 1 year old and the oldest being 82 years old. The stone locations were calyceal; 221 patients (43.68%), pelvis; 155 patients (30.63%), and multiple; 130 patients (25.69%). The stone size was divided into two category: >20 mm; 372 patients (73.52%) and <20 mm; 134 patients (26.48%). The mean operation time was 84±41.24 minutes with the shortest being 30 minutes and the longest being 239 minutes. Supine PCNL was performed with single puncture in 495 patients (97.83%) and with multiple punctures in 11 patients (2.17%). The total stone free rate was 95.65%. 22 patients undergone another stone removal procedures after receiving supine PCNL (2nd PCNL; 6 (1.18%), ESWL; 16 (3.16%). The mean post-operative length of hospital stay was 4.1±1.48 days with the shortest being 1 day and the longest being 8 days. 28 minor complications such as infections and blood loss were recorded with only 1 case of colon perforation which is considered to be major complication.
Conclusions : Supine PCNL in our centre is shown to have high stone free rate, short hospital stay, and low post-operative complications. These outcomes are the key component of this minimally- invasive procedure. Thus, mark the effectiveness and safety of supine PCNL in our centre.
Knowledge, Attitudes, and Perceptions toward COVID-19 Vaccinations in Saudi Population
Authors: Al Tulaihi Bader , Salamah Ghalia Mustafa , Alshahrani Turki Mari , Haikel Kholoud A. Bin , Al Eraij Sara Mohammed , Alsaeed Roqaih Raja , Alilaj Muath Owaidh , Alzaid Tufol Abdullah
Published: May 2023

AIM: The objective is to explore the general perception, knowledge, and attitude of people in Saudi Arabia toward the COVID-19 vaccination.

METHODS: An observational and cross-sectional study was conducted with 332 Saudi adult population attending primary health centers in King Abdul-Aziz Medical City, Riyadh, Saudi Arabia, between May and July2021 using a self-administered questionnaire. All adults, equal, or older than 18 years old of both genders during the period of the study were included and the only exclusion criteria are the age and patient with psychiatric disorder. We use convenience-sampling technique, due to the difficulty to generate sampling frame. Data are going to be entered and analyzed using Statistics Package for the Social Science version 21 software in August 2021.

RESULTS: Majority of participants (93.4%) had good knowledge about COVID-19 vaccines, regarding attitude more than 50% have positive attitude toward vaccination. Despite this high level on acceptance 48.5% of the participant in this study disclosed that they are not aware of vaccine side effects. With regard to perception, 66.9% of our study subjects believed that vaccination is necessary to eradicate COVID-19 pandemic. Furthermore, 72.4% thought that everyone should be vaccinated, starting with general public 74.5%, then health worker 57.9%.

CONCLUSION: Almost most of Saudi population aware about the COVID-19 vaccines. Most Saudi people knew about it through media. A long-term side effect of getting vaccines is the main obstacles toward vaccine acceptance.
Relationship between Clusters of Differentiation 4 Count and Type of Human Papilloma Virus with Giant Condyloma Acuminata
Authors: Rohanda Boy Ardi , Hutapea Richard , Nadeak Kristina
Published: May 2023

BACKGROUND: Condyloma acuminata (CA) is a sexually transmitted infection caused by the human papilloma virus (HPV). HPV infection is increasing in immunosuppressed patients which causes the development of CA lesions to be longer, recurrent, and larger. Clusters of differentiation 4 (CD4) count showed an association with the occurrence of giant condyloma acuminata (GCA).

AIM: The aim of the study was to determine the relationship between CD4 count and type of HPV with GCA.

SUBJECTS AND METHODS: This study was an analytic and observational study with a cross-sectional design with 20 human immunodeficiency virus-infected subjects (10 GCA and 10 non-GCA) selected using the consecutive sampling technique. CD4 examination using blood samples which were analyzed using fluorescence-activated cell sorting. CA lesions were taken using a shave biopsy technique and then the HPV type was examined using the polymerase chain reaction method.

RESULTS: The majority of the study subjects were male with GCA 7 people (41.2%). The most age group was 26–35 years old with GCA 6 people (66.7%). The education of the subjects was mostly senior high school with GCA 9 people (56.2%). The employment of the subjects was mostly service and sales personnel with GCA 4 people (57.1%). Based on the location of the GCA lesions, there were 4 people (57.1%) in the genital area and 6 people (46.2%) in the anal area. A total of 9 people (90%) with GCA had severe immunosuppression. The results of the analysis showed that there was a significant relationship between CD4 count and GCA (p < 0.001). The most common HPV type in GCA was HPV-11, amounting to 6 people (46.2%). The results of the analysis showed that there was no significant relationship between the type of HPV and GCA (p = 0.275).

CONCLUSION: There is a significant relationship between CD4 count with GCA and there is no relationship between type of HPV with GCA.