bluuebunny/crossref_metadata_2025 huggingface dataset:
O impacto da hierarquia de memória sobre a arquitetura IPNoSys
Authors:   , Damasceno Alexandro Lima
Published: February 2025

Aolongo dos anos,coma ascensão das tecnologias, a busca por melhorias no desempenho
dos sistemas computacionais é algo notável. Os sistemas computacionais evoluíram
tanto em capacidade de processamento como em complexidade das arquiteturas
implementadas. Nesses sistemas é crucial a utilização de memórias uma vez que elas são
responsáveis pelo armazenamento de dados que serão processados. Considerando um
ambiente ideal, as memórias deveriam ter uma capacidade de armazenamento ilimitado,
o acesso de dados imediato e o custo por bit extremamente baixo. Porém nos sistemas
reais as memórias não apresentam essas características. Capacidade de armazenamento,
velocidade e custo por bit são fatores que crescem proporcionalmente entre si. Uma
técnica que é utilizada para balancear esses fatores e melhorar o desempenho dos
sistemas computacionais é a hierarquia de memória. No cenário de novas tecnologias
e propostas de novas organizações de processadores, um modelo que vem sendo
adotada pelos projetistas de sistemas computacionais é o uso de MPSoCs (sistemas
multiprocessados integrados em chip), que apresenta uma maior eficiência energética e
computacional. Nesse cenário com muitos elementos de processamento, a utilização
de redes em chip (NoC - networks-on-chip) se mostra mais eficiente que o uso de
barramentos. Uma NoC consiste em um conjunto de roteadores e canais interligados
formando uma rede chaveada. Os núcleos são conectados aos terminais da rede e
a comunicação ocorre pela troca de pacotes. Essas NoCs foram tradicionalmente
projetadas exclusivamente para a comunicação em SoCs. Entretanto, um projeto de uma
arquitetura não convencional resolveu integrar processamento e comunicação em uma
NoC. Essa arquitetura é conhecida por IPNoSys. A arquitetura IPNoSys (Integrated
Processing NoC System) é um processador não convencional que utiliza redes em chip e
implementa unidades de processamento e roteamento para tratar e processar instruções.
Aproveita as características das NoCs, como escalabilidade e comunicação paralela, para
implementar de maneira eficiente execuções de programas que exploram paralelismo em
nível de threads. Atualmente, a arquitetura IPNoSys possui quatro memórias fisicamente
distribuidas nos cantos da rede, mas que representam um endereçamento unificado.
Cada módulo de memória é associado a uma unidade de acesso que se encarregam
de gerenciá-la. Diante da atual organização de memórias da IPNoSys, esse trabalho
desenvolveu um novo sistema de hierarquia de memórias para o IPNoSys e investigou
os possíveis impactos sobre o desempenho e o modelo de programação.
Modelagem para simulação em regime permanente e dinâmico do DFIG no ATP-EMTP
Authors:   , Rocha Yago da Silva Pires
Published: February 2025

Atualmente, vários países já esboçam propostas iniciais para aliviar a demanda de fontes não renováveis para a produção de energia, e algumas delas diz a respeito às políticas de desenvolvimento de energias renováveis. No Brasil, o Rio Grande do Norte (RN) é o estado líder em produção de energia eólica, com 224 empreendimentos em operação, com capacidade de produzir até 6,8 gigawatts. Além disso, há ainda 63 parques eólicos em construção e 85 já contratados. Esses geradores acoplados a turbinas formam o que se denomina aerogeradores, que transformam a ação mecânica recebida da força dos ventos em energia elétrica para o sistema. O gerador de indução duplamente alimentado (DFIG) possibilita um controle das potências ativa, reativa e fator de potência da máquina, além disso, é de baixo custo e exige pouca manutenção. O trabalho tem por objetivo analisar matematicamente o DFIG através de modelos que reflitam os mesmos cálculos realizados pelo software ATP-EMTP tanto em regime permanente como em regime dinâmico, conhecendo o comportamento transitório das grandezas elétricas em vários pontos da topologia DFIG e posteriormente comparar os resultados obtidos com os modelos desenvolvidos nas simulações. A dissertação se basear na simulação de uma máquina DFIG em diferentes velocidades de operação em regimes permanente e dinâmico. O trabalho se diferencia pelo controle de potência da máquina através de variação de tensões de saída do rotor, sem auxilio de conversores. Para isso inicialmente foi feita a modelagem considerando alguns parâmetros dos aerogeradores comerciais de velocidade variável, junto com os principais componentes da rede elétrica. Posteriormente realizaram-se simulações computacionais para obter o comportamento do DFIG, e por fim, foi realizada uma análise dos efeitos que produzem cada tipo de operação da máquina, analisando fluxo de potência e o nível de tensão em regime permanente e dinâmico. Para atingir os objetivos, a modelagem do sistema foi simulada nos softwares ATP-EMTP e MATLAB®. Os resultados obtidos pela simulação validaram a modelagem matemática adotada para os casos de regime permanente e dinâmico, comprovando a eficiência do modelo em entregar a potência desejada. Os resultados obtidos nesta dissertação mostraram a funcionalidade do ATP para a simulação de um DFIG, tornando possíveis diversos estudos de melhoria no desempenho do sistema
Yueju Pill Inhibits Apoptosis by Regulating the SCF/c-Kit/PI3K/AKT Signaling Pathway to Ameliorate Functional Dyspepsia
Authors: Gu Yaru , Biao Yaning , Liu Chenxu , Zhang Yufang , Gao Ya , Xue Yucong , Zhang Yixin
Published: February 2025

Objective:

This study aimed to investigate the therapeutic effect of Yueju Pill (YJP)
on functional dyspepsia (FD) rats and its mechanism of promoting gastrointestinal motility.

Methods:

We replicated FD rat models using classical tail pinching and irregular feeding for 14
days. After 28 days of YJP treatment, we measured the gastric emptying rate and intestinal propulsion
rate of the rats. Hematoxylin-eosin (H&E) staining was used to observe the pathological
damage in the gastric antrum. The serum levels of related brain-gut peptides (BGPs) were determined
using the enzyme-linked immunosorbent assay (ELISA). Furthermore, we detected
the expression of proteins related to the SCF/c-Kit/PI3K/AKT signaling pathway through
Western blot and immunohistochemistry. Finally, we assessed the levels of apoptosis using the
TUNEL assay.

Results:

YJP improved gastric emptying and small intestine propulsion rates while reducing
gastric tissue injury in FD rats. Moreover, YJP increased the levels of gastrin (GAS) and
ghrelin (Ghrelin) and decreased the levels of cholecystokinin (CCK) and vasoactive intestinal
peptide (VIP). YJP also elevated the levels of SCF, c-kit and Bcl-2, promoted the phosphorylation
of PI3K and AKT, and inhibited the expression of Bax.

Conclusion:

YJP achieved the effect of FD treatment by regulating the SCF/c-Kit/PI3K/AKT
pathway, providing a theoretical basis for the clinical treatment of FD.
YY2 Serves as a Novel Prognostic Biomarker Correlated with Immune Microenvironment and Glycolysis in Esophageal Carcinoma
Authors: Gou Haimei , Yang Hui , Cheng Jiao , He Shuang , Luo Can , Chen Xin , Zhong Xiaowu
Published: February 2025

Background:

Yin Yang 2 (YY2) plays a pivotal role in various tumorigenic processes;
however, its specific involvement in esophageal carcinoma (ESCA) remains elusive. This study
aims to investigate the expression and potential functional significance of YY2 in ESCA.

Methods:

The expression and functions of YY2 in ESCA were analyzed using a broad range of bioinformatics
databases and tools, including TCGA, TIMER, TISIDB, QUANTISEQ, cBioPortal,
DNMIVD, LinkedOmics, DAVID, GSEA, GEPIA2, LASSO, miRWalk, miRDB, and TargetScan.
Furthermore, RT-qPCR, immunohistochemical staining, western blot, CCK8 assay, and wound
healing assay were employed to validate the involvement of YY2 in ESCA pathogenesis.

Results:

Bioinformatics analyses revealed that the YY2 gene is upregulated in ESCA tissues, with its
high expression significantly associated with poor prognosis and elevated levels of M2 macrophages,
NK cells, Tregs, CTLA4, TIGIT, and Siglec-15. Validating the ESCA samples demonstrated that
knockdown of YY2 effectively inhibited cell proliferation and migration in ESCA cells. The biological
functions of YY2 and its co-expressed genes were primarily associated with transcriptional regulation,
DNA methylation, glycometabolism, and ubiquitination. Moreover, the regulatory network of YY2 in
the glycolysis pathway was found to involve multiple genes and miRNAs. Finally, a prognostic model
based on YY2 and its associated glycolysis genes revealed a strong inverse correlation between higher
risk scores and lower survival rates in esophageal adenocarcinoma (EAC).

Conclusion:

YY2 may serve as a promising prognostic biomarker and an innovative therapeutic
target for patients with ESCA, regulating cell proliferation, migration, immune microenvironment,
and glycolysis.
Harary Spectra and Energy of Certain Classes of Graphs
Authors: Ashoka Kuruba , Parvathalu Bolle , Arumugam Subramanian
Published: February 2025

Aims:

To investigate the Η-eigenvalues and Η-energy of various types of graphs,
including κ-fold graphs, strong κ-fold graphs, and extended bipartite double graphs and establish relationships between the Η-energy of κ-fold and strong κ-fold graphs and the Η-energy of
the original graph G, we explore the connection between the Η-energy of extended bipartite
double graphs and their ordinary energy and find the graphs that share equienergetic properties
with respect to both the ordinary and Harary matrices.

Background:

The Η-eigenvalues of a graph G are the eigenvalues of its Harary matrix Η(G).
The Η-energy εΗ(G) of a graph, G is the sum of the absolute values of its Η-eigenvalues. Two
connected graphs are said to be Η-equienergetic if they have equal Η-energies. They are said to
A-equienergetic if they have equal A-energies. Adjacency and Harary matrices have applications in chemistry, such as finding total Π-electron energy, quantitative structure-property relationship (QSPR), etc.

Objective:

We determined the Η-spectra of κ-fold graphs, strong κ-fold graphs and extended
bipartite double graphs and established connections between the Η-energy of different types of
graphs and their original graph G for investigating the relationship between the Η-energy of
extended bipartite double graphs and their ordinary energy and the graphs that share equienergetic properties with respect to both the adjacency and Harary matrices.

Methods:

Spectral algebraic techniques are used to calculate the Η-eigenvalues and Η-energy
for each type of graph and compare the Η-energies of different graphs to identify the equienergetic properties and derive relationships between the Η-energy of extended double cover graphs
and their ordinary energy.

Results:

We determined the Η-spectra of κ-fold graphs, strong κ-fold graphs and extended bipartite double graphs and established relationships between the Η-energy of κ-fold and strong
κ-fold graphs and the Η-energy of the original graph G. Then, we explored the connection between the Η-energy of extended bipartite double graphs and their ordinary energy and presented
graphs demonstrating equienergetic properties concerning both adjacency and Harary matrices.

Conclusion:

The study provides insights into the Η-eigenvalues, Η-energy and equienergetic
properties of various types of graphs. The established relationships and connections contribute
to a deeper understanding of graph spectra and energy properties and the findings enhance the
theoretical framework for analyzing equienergetic graphs and their spectral properties.

Scope:

Possible extensions of this research could include investigating additional types of
graphs and exploring further explicit connections between different graph energies and spectral
properties.
Harary matrices are distance-based matrices, which can model distances between atoms in molecular structures and could be useful in organic synthesis to predict how molecular structures
behave.
Investigation of Norfloxacin Adsorption and Detection in Wastewater Utilizing Hyaluronic Acid and Dopamine-modified Mesoporous Carbon
Authors: Ge Yanhui , Liu Yubo
Published: February 2025

Objective:

The increasing environmental pollution from antibiotics poses a significant
threat to public health, and this is a critical issue that requires immediate attention.

Methods:

In this study, a simple and effective surface modification technique was presented using
hyaluronic acid-dopamine conjugate (HA-DA) to impart anti-biofouling properties to basin-concave
mesoporous carbon (BCMC). The synthesized materials were characterized by scanning electron
microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared (FT-IR)
spectroscopy, nitrogen physisorption, and thermogravimetric analysis (TGA). The optimum adsorption
performance of the synthesized materials was investigated via adsorption isotherms and kinetics
experiments. Afterward, the obtained particles were used as solid-phase extraction subjects for Norfloxacin
(Nor) analysis in wastewater.

Results:

After being quantified by high-performance liquid chromatography (SPE-HPLC), the synthesized
BCMC@HA-DA demonstrated an impressive binding capacity of 14.80 mg/g for Nor. Following
six adsorption-desorption cycles, the adsorption revercory remained at 81.65%.

Conclusion:

The prepared BCMC@HA-DA could successfully be concentrated Nor from
wastewater, indicating significant potential for addressing environmental biofouling issues.
Exploiting Gene Expression Signatures in Breast Cancer Cell Lines to Unveil Novel Drug Candidates and Synergistic Combinations
Authors: Liu Hsueh-Chuan , Weng Chia-Wei , Ng Ka-Lok
Published: February 2025

Aim:

This study aimed to study breast cancer, the most common cancer affecting women
worldwide, using one primary and two metastatic breast tumor cell lines to identify therapeutic
drugs.

Background:

Investigating the changes in gene expression triggered by drugs offers a robust method
for uncovering potential new treatments. Through the analysis of the impacts of drugs on gene activity,
scientists can unravel the molecular mechanisms within cells, comprehend the effects of
drugs, identify chances for drug repositioning, and foresee patient outcomes to treatments.

Objective:

Our approach has involved two main strategies: analyzing drug-perturbed gene expression
profiles and leveraging drug-induced gene expression profiles. Firstly, we have assessed how
drugs affect the expression of target genes in a dose-dependent manner, determining whether they
inhibit or activate gene expression. This analysis could inform the identification of new potential
drugs. Secondly, we have grouped drugs based on their expression profiles to explore potential synergistic
effects.

Methods:

Our methodology has involved quantifying gene profile changes relative to drug dosage,
categorizing effects as up-regulating or down-regulating, and employing functional enrichment with
cancer hallmark annotations to predict drugs with potential for cancer treatment. Additionally, we
have determined the optimal number of drug groups with similar effects on gene expression and explored
their mechanisms of action through cancer hallmark annotations.

Results:

By analyzing dose-dependent gene expression, we have found that seven, three, and five
drugs may induce similar sets of up-regulated and down-regulated genes in Hs-578-T, MCF7, and
MDA-MB-231 cell lines, respectively. Clustering and functional enrichment analyses have suggested
a shared molecular mechanism of action among these drug candidates.

Conclusion:

We have thus categorized drugs with opposing gene expression profiles and proposed
new drug candidates for breast cancer treatment based on cancer hallmark annotations. Moreover,
our study has uncovered synergistic drug combinations, including those utilizing FDA-approved
drugs, for primary and metastatic breast cancer cell lines.
Analysis of SCB-DB Algorithm for Various Characteristic Parameters
Authors: Thakur Diksha , baghel Vikas , Talluri salman Raju
Published: February 2025

Introduction:

The performance of a standard Capon beamformer for dual beams (SCBDB)
is analyzed against simultaneous variations in the direction and power of interference. The
performance metrics of SCB-DB are SLL, maximum SLL, 3-dB beamwidth and beamwidth between
first minimas.

Method:

In SCB-DB, the standard SCB utilizes an extra constraint to ensure that unity gain is preserved
for the second desired signal. The SLL management, along with dual beams (SCB −
DBSLL), involves the sampling of angles within the sidelobe area, and the powers associated with
these sampled angles are restricted to a predetermined level.

Results:

The SCB − DBSLL configuration demonstrated notable enhancements, achieving approximately
a 63% reduction in side lobe levels for both beams, decreasing from -8 dB to -21.846 dB.

Conclusion:

Additionally, maximum SLL improved by 64% lowering from -5.48 dB to -9 dB.
Green Energy Revolution: Production of Environmentally Friendly Sustainable Biofuels using Yeasts with the Help of Artificial Intelligence
Authors: Alavian Firoozeh , Khodabakhshi Fatemeh
Published: February 2025

Artificial Intelligence (AI) has made significant advancements in recent years in the development
and genetic editing of living organisms, especially yeasts, which play a key role in producing
biofuels. This article examines how AI contributes to accelerating the growth of yeast strains
for biofuel production and progress toward sustainable development. In this review, extensive
searches were conducted using keywords such as artificial intelligence, yeast, biofuel, and fermentation
to find articles relevant to the research objective. The results revealed that using AI-modified
yeasts to create alcohol allows for higher yield production, heavy metal absorption and conversion,
more efficient use of bioplastics, and lactic acid synthesis. This turns them into a reliable and environmentally
friendly alternative to fossil fuels. Thus, Artificial Intelligence plays a significant role in
advancing yeasts for biofuel production. These advancements lead to the development of yeast
strains with higher biofuel production yields and a reduction in biological pollution.
Identifying High-Priority Ethical Challenges for Precision Emergency Medicine: Nominal Group Study
Authors: Rose Christian , Shearer Emily , Woller Isabela , Foster Ashley , Ashenburg Nicholas , Kim Ireh , Newberry Jennifer
Published: February 2025

Background

Precision medicine promises to revolutionize health care by providing the right care to the right patient at the right time. However, the emergency department’s unique mandate to treat “anyone, anywhere, anytime” creates critical tensions with precision medicine’s requirements for comprehensive patient data and computational analysis. As emergency departments serve as health care’s safety net and provide a growing proportion of acute care in America, identifying and addressing the ethical challenges of implementing precision medicine in this setting is crucial to prevent exacerbation of existing health care disparities. The rapid advancement of precision medicine technologies makes it imperative to understand these challenges before widespread implementation in emergency care settings.

Objective

This study aimed to identify high priority ethical concerns facing the implementation of precision medicine in the emergency department.

Methods

We conducted a qualitative study using a modified nominal group technique (NGT) with emergency physicians who had previous knowledge of precision medicine concepts. The NGT process consisted of four phases: (1) silent generation of ideas, (2) round-robin sharing of ideas, (3) structured discussion and clarification, and (4) thematic grouping of priorities. Participants represented diverse practice settings (county hospital, community hospital, academic center, and integrated managed care consortium) and subspecialties (education, ethics, pediatrics, diversity, equity, inclusion, and informatics) across various career stages from residents to late-career physicians.

Results

A total of 12 emergency physicians identified 82 initial challenges during individual ideation, which were consolidated to 48 unique challenges after removing duplicates and combining related items. The average participant contributed 6.8 (SD 2.9) challenges. These challenges were organized into a framework with 3 themes: values, privacy, and justice. The framework identified the need to address these themes across 3 time points of the precision medicine process: acquisition of data, actualization in the care setting, and the after effects of its use. This systematic organization revealed interrelated concerns spanning from data collection and bias to implementation challenges and long-term consequences for health care equity.

Conclusions

Our study developed a novel framework that maps critical ethical challenges across 3 domains (values, privacy, and justice) and 3 temporal stages of precision medicine implementation. This framework identifies high-priority areas for future research and policy development, particularly around data representation, privacy protection, and equitable access. Successfully addressing these challenges is essential to realize precision medicine’s potential while preserving emergency medicine’s core mission as health care’s safety net.
Understanding trauma informed support for people affected by dementia: an analysis of telephone helpline call-logs (Preprint)
Authors: Harkess-Murphy Eileen , Macrae Rhoda , Brown Margaret , Hall Jennifer
Published: February 2025

BACKGROUND

People with dementia and their caregivers experience significant psychological distress and may be at risk of trauma when coping mechanisms are overwhelmed. Specialist dementia helplines play a vital role by offering immediate support and information, however, little is known about how call handlers account for potential trauma in their responses. This study explored the extent to which trauma-informed principles are evident in the responses provided by call handlers on the UK’s only 24-hour dementia helpline.

OBJECTIVE

To explore the type and nature of calls to the only UK 24-hour dementia helpline and the extent to which trauma-informed principles are evident within helpline staff responses to carers and people with dementia.

METHODS

A retrospective analysis was conducted on 200 anonymised call-logs from Alzheimer Scotland’s 24-hour helpline. Data from call-logs were analysed using framework analysis informed by trauma-informed principles (safety, trustworthiness & transparency, choice, collaboration, and empowerment). Data is also reported by theme frequency and theme strength: theme frequency captured how often each theme appeared across the dataset (expressed as a percentage), while theme strength represented the researcher’s subjective assessment of the theme’s intensity within each call-log, measured on a Likert scale.

RESULTS

Most calls (86%) were made during daytime hours by a ‘carer/family member/friend,’ with 'emotional support' and 'carer stress' being the primary reasons for contact. Call-log responses aligned with several trauma-informed principles, with ‘collaboration’ being the most frequent response for daytime calls (69.5%) and 'safety' for night-time calls (79.4%). Across all responses, 'empowerment' emerged as the strongest theme, characterised by empathetic, non-judgmental responses that acknowledged caller strengths. Overall, 'collaboration' (27%) was the most frequently observed theme, reflecting efforts to share knowledge and engage callers with relevant resources. Call handlers tailored their approach based on the caller’s identity, with responses to ‘carers/family/friends’ most frequently displaying collaboration (70.4%). Analysis of calls from individuals seeking information for themselves revealed collaboration and empowerment were the most frequent themes (73.7%).

CONCLUSIONS

The findings highlight the helpline's role as a critical resource for emotional support for individuals experiencing stress. They also contribute to understanding how a trauma-informed approach can be effectively applied in such interactions. Implications for developing a trauma-informed framework to guide helpline responses, particularly for high-risk groups such as dementia family carers, are explored.

CLINICALTRIAL

N/A
Web-Based Continuing Education Improves New Diagnoses of Alzheimer’s Disease in Claims Data: A Retrospective Case-Control Study (Preprint)
Authors: Lucero Katie , Finnegan Thomas , Borson Soo
Published: February 2025

BACKGROUND

Alzheimer’s disease (AD) presents significant challenges to healthcare systems worldwide. Early and accurate diagnosis of AD is crucial for effective management and care, as it enables timely treatment interventions that can preserve cognitive function and improve patient quality of life. However, there are often significant delays in diagnosis. Continuing medical education (CME) has enhanced physician knowledge and confidence in various medical fields, including AD. Notably, web-based CME has been shown to positively influence physician confidence, which can lead to changes in practice and increased adoption of evidence-based treatment selection.

OBJECTIVE

This study investigated the impact of a targeted, web-based CME intervention on healthcare providers’ confidence, competence, and real-world outcomes in diagnosing early AD.

METHODS

The study employed a two-phase design. Phase I used a pre-post assessment to evaluate immediate changes in knowledge and confidence before and after CME participation. Phase II involved a retrospective, matched case-control study to examine the impact of CME on AD diagnoses in claims data.

RESULTS

A one-way analysis of variance (ANOVA) showed a significant effect of CME for change in the volume of AD diagnoses, F(1, 900) = 5.50, P = .0192. Compared to controls, CME learners were 1.6 times more likely to diagnose AD, resulting in an estimated net increase of 7939 new diagnoses annually. Post-CME, being confident was associated with a greater likelihood of diagnosing AD (odds ratio [OR] 1.64; 95% CI 0.92, 2.92; P = .09; n = 219).

CONCLUSIONS

Web-based CME participation is associated with increased real-world AD diagnoses. Findings offer a mechanism to explain the changes in real-world practice seen as a result of the CME intervention, which improves skills and confidence.
Exploring the impact of Caring Contacts on the stress and distress of Veterans and Service Members: Protocol for a Randomized Controlled Trial (Preprint)
Authors: Wright Barbara , Evanson Anna , Casey Cameron , Law Keyne C. , Rogers Andrew H. , Comtois Katherine Anne
Published: February 2025

BACKGROUND

Suicide is a recognized global public health problem that is not improving in the United States. Veterans and service members are at particular risk. Caring Contacts is a simple, scalable intervention that reduces suicide risk in high-risk populations and has demonstrated acceptability in military and veteran samples. However, little is known about the mechanisms of Caring Contacts or its applicability to lower risk populations.

OBJECTIVE

The aims of this study are to 1) evaluate if receiving Caring Contacts reduces suicide risk for veterans recruited for stress or distress via Ecological Momentary Assessment (EMA; suicide urges and wish to live and die) and survey measures of suicidal ideation (Harkavy-Asnis Suicide Scale) and cognitions (Suicide Cognitions Scale); 2) examine diverse veterans’ experiences with Caring Contacts; 3) evaluate if receiving Caring Contacts reduces distress (depression, substance use consequences, hopelessness, defeat, and psychological pain); and 4) identify potential mechanisms of action for Caring Contacts (mattering, connectedness, social responsibility, and entrapment). With the use of EMA, this study will be the first to investigate mechanisms of Caring Contacts both as they are received in real-time as well as over one year.

METHODS

In this randomized controlled trial (RCT), 510 veterans or service members experiencing stress or distress will be offered the best available resources and randomized into one of three study conditions: (1) 12 months of Caring Contacts and monthly EMA, (2) 12 months of Caring Contacts without monthly EMA, or (3) 12 months of monthly EMA alone. The Caring Contacts conditions will receive 13 Caring Contacts messages over the course of the study year. A subset of participants from each condition will be asked to complete a qualitative interview after the 12-month follow-up about their experiences completing EMA and receiving Caring Contacts messages.

RESULTS

Recruitment for this trial started in April 2024 and will end in May 2025. Final quantitative data collection will be completed by July 2026, two months after the final 12-month follow-up date. Data from qualitative interviews will be collected until September 2026.

CONCLUSIONS

This study will be the first RCT evaluating the impact of Caring Contacts on service members and veterans not recruited for suicidality. If effective, our findings will demonstrate that Caring Contacts are beneficial for multiple forms of psychological distress as well as suicide risk. In addition, we will evaluate potential mechanisms explaining the effect of Caring Contacts and the utility of EMA as a primary measure of outcome in suicide research trials.

CLINICALTRIAL

We are on clinicaltrials.gov at ID NCT06136234. This trial is currently enrolling participants.
A Study on Department of Trade in China
Authors: LU CHENG
Published: February 2025

This study investigated and organized the structure and operating situation of trade departments at major Chinese universities to present the development direction of trade and education at universities in Korea. First, it introduced the types of master's courses in general subjects in China. Through the two ways of the Chinese Ministry of Education's Official and Private Ranking, selected international economy and trade and the Top 10 among numerous universities, introducing the opening and faculty of 12 schools. He also looked at the state of China's trade and master's degree. He explained the establishment of the MIB master's degree in international trade at the University of Foreign Economics, Nanjing University, and Nanjing University according to the degree of official information disclosure among the 12 universities. Also, it was compared with The Korean Department of Trade's course.
According to the research results, the Chinese MIB Master emphasizes practicality, and the Master of International Trade of the University of Foreign Economics and Trade, Nanjing University, and Nanjiang University are all political and Marxist philosophy, foreign languages, and economics as compulsory subjects, each school has different elective subjects. Referring to the study on the Korean Department of Commerce in Imsing-ju (2024), we also looked at the commonalities and differences between the departments of commerce in China and Korea. Korean trade and official names are numerous, and Chinese names are unified. The number of trade departments in Korea is decreasing, but China has remained the same. The trade departments of the two countries have been investigated into the fact that in the future, digital trade will be the focus of family restructuring.
LA PERSPECTIVA ECOLÓGICA DE LA GOBERNANZA DE LA FORMACIÓN UNIVERSITARIA CHILENA. UNA PROPUESTA DE MODELO ANALÍTICO
Authors: Gaete Quezada Ricardo
Published: February 2025

Las transformaciones universitarias propiciadas por el modelo de formación por competencias y las estrategias formativas centradas en el estudiantado, favorecen la pertinencia laboral demandada por las organizaciones productivas y de servicio. Esto configura un desafío importante para incorporar nuevos actores, procesos y estructuras en la toma de decisiones relacionada con el servicio educativo entregado por las universidades contemporáneas. El estudio analiza las características y elementos fundamentales de la gobernanza incorporados en los modelos educativos, como principales documentos institucionales que orientan la formación universitaria en Chile. Mediante un análisis de contenido cuantitativo de tipo descriptivo, se examina una muestra de universidades estatales chilenas. Se identifica la presencia de elementos de gobernanza universitaria en la mayoría de la documentación institucional examinada y se concluye que la mayor participación de elementos provenientes desde los niveles ecológicos supranacional y exosistema respectivamente, proporcionarán mejores niveles de legitimidad externa y efectividad interna del proceso formativo universitario.
Síndrome de Dyke-Davidoff-Masson como causa de hemiatrofia cerebral: a propósito de un caso clínico
Authors: Salazar Vaz José Emilio , Gonzalez Ximena , Méndez Tammara
Published: February 2025

Introducción: en la aproximación diagnóstica de cuadros de hemiatrofia cerebral, se debe considerar el síndrome de Dyke-Davidoff-Masson, el cual reúne características clínicas y, sobre todo, imagenológicas distintivas. A propósito de ello, se presenta un caso clínico de inicio en la infancia con detección en la edad adulta.
Presentación del caso: paciente de sexo masculino de 46 años que como antecedente relevante presentó, a los seis meses de vida, infección por herpes simple. Desde entonces, desarrolló déficit motor del hemicuerpo izquierdo, discapacidad intelectual y epilepsia refractaria. Se valora con neuroimagen que muestra hallazgos compatibles con síndrome de Dyke-Davidoff-Masson.
Discusión: el síndrome de Dyke-Davidoff-Masson (DDMS) fue descrito por primera vez en 1933 como un cuadro de hemiatrofia cerebral. Se le considera un síndrome epiléptico raro que se puede presentar de forma congénita o adquirida y que se caracteriza por hallazgos clínicos e imagenológicos típicos. Se puede presentar con crisis epilépticas, déficit motor o sensitivo contralateral y trastornos intelectuales. A nivel imagenológico se suele observar atrofia de un hemisferio cerebral, hipertrofia ósea ipsilateral e hiperneumatización de los senos adyacentes.
Su tratamiento es sintomático y basado en un abordaje multidisciplinario.
Conclusiones: se presentó un caso de síndrome de Dyke-Davidoff-Masson de inicio en la infancia y que, a diferencia de lo descrito habitualmente, comprometió el hemisferio derecho.
Peningkatan Daya Saing UKM Industri Kreatif Sebagai Salah Satu Produk Unggulan Daerah Desa Pudak Kabupaten Muaro Jambi dalam Memasuki Era MEA
Authors: Setiawan Dedy , Utomo Pradita Eko Prasetyo , Fitri Lucky Enggrani
Published: February 2025

Berdasarkan prasurvey dan hasil diskusi dengan pihak mitra, permasalahan-permasalahan utama yang dihadapi oleh mitra pada saat ini adalah: (1). UKM Mitra Pengabdian Inovasi Wira Desa dalam hal mempromosikan produk-produknya masih mengunakan cara yang sangat sederhana sekali (bersifat Offline) sehingga jangkauan pemasaran tidak begitu luas hanya sebatas di dalam provinsi Jambi saja. Pemasaran produknya yang di lakukan oleh mitra hanya dari mulut ke mulut (word of mouth), belum menggunakan media teknologi berbasis online (E-Commerce) yang dapat dengan mudah membantu dalam memasarkan produknya (2). Mitra UKM Pada desa Pudak membutuhkan pelatihan tentang manajemen pemasaran, manajemen produksi dan permodalan serta pelatihan dalam penggunaan teknologi khususnya teknologi informasi dan komunikasi untuk digunakan dalam membantu tatakolah manajemen pada mitra dan memasarkan produk-produknya secara online (3). Kemasan untuk produk yang dimiliki mitra kurang menarik dan alat kemasan yang kurang baik. Target dari pengabdian Inovasi Wira Desa ini adalah bagaimana cara meningkatkan mutu manajemen tata Kelola dan Produktivitas sale pisang dan Keripik Tempe yang di miliki oleh Mitra sehingga pada akhirnya dapat meningkatkan kesejahteraan Mitra dan masyarakat yang ada di sekitarnya sesuai dengan apa yang telah dianalisis dan diskusikan dengan pihak mitra secara sederhana. Adapun luaran dari kegiatan pengabdian masayarakat ini adalah Metode dalam tata kelola manajemen bagi meningkatkan Produktivitas Sale Pisang dan keripik pisang serta penyedian kemasan yang higenis dan menarik dan pembuatan teknologi tepat guna berupa Sistem E-Commerce Berbasis web selain itu target pengabdian ini, dalam besinergi dengan kegiatan Merdeka Belajar Kampus Merdeka (MBKM) Universitas Jambi yaitu Desa Binaan dan Magang dan Studi Independen. Pengabdian ini dilaksanakan selama 5 bulan yang dimulai dari bulan Agustus sampai dengan bulan Desember 2021. Pada tahap awal, tim pengbadian akan melakukan koordinasi dengan mitra untuk mengatur waktu pelaksanaan pengabdian khususnya dalam hal pelaksanaan pelatihan. Setelah kegiatan ini dilaksanakan selanjutnya tim pengabdian bersama-sama memilih bentuk kemasan yang tepat untuk produk sale pisang mitra dan selanjutnya pembuatan aplikasi E-Commerce. Pelaksanaan kegiatan ini, pada saat ini telah melakukan pelatihan, pembuatan web dan pemberiaan bantuan alat pendukung produksi bagi mitra, agar pelaksanaan bengabdian ini benar-benar bermanfaat, tim pengabdian akan melakuakn pemantauan terhadap hasil output dari pengabdian ini
Penerapan Aplikasi Koperasi Berbasis Digital pada BMT Bina Insan Sejahtera dan Koperasi Cendikia Pinang Masak
Authors: Hizazi Achmad , Mansur Fitrini , Jumaili Salman , Safelia Nela , Rozi Syamsyida
Published: February 2025

BMT Bina Insan Sejahtera dan Koperasi Cendikia Pinang Masak sebagai lembagai keuangan mikro memiliki kelemahan yang serupa dalam pengelolaan pencatatan keuangan. Meskipin laporan keduanya sudah dilakukan dengan benar tetapi pelaporan keuangan masih memerlukan waktu yang lama, karena masih dikerjakan berbasis mikrosoft excel. Hal ini menyebabkan pelaporan menjadi lama dan kurang akurat. Karena itu diperlukan transisi pengelolan aplikasi yang bersifat online, sehingga pengelola BMT, Bina Insan Sejahtera, koperasi Cendikia Pinang Masak dan anggotanya dapat merasakan kualitas layanan yang lebih baik
Pelatihan Pembuatan Konten dan Digital Marketing Produk UMKM di Kecamatan Palayangan
Authors: Chairunnisa Fitri , Aira Dian mala fithriani , Rosyid Garry Yuesa , Rosita Sry , Hasbullah Husni
Published: February 2025

Pelatihan pembuatan konten menggunakan platform digital yang ditujukan untuk kelompok masyarakat didalam meningkatkan volume penjualan para pelaku UMKM kecamatan palayangan. Target yang ingin dicapai yaitu implementasi pendampingan para pelaku UMKM dengan meningkatkan kemampuan pelaku UMKM dalam memasarkan produk mereka secara efektif melalui platform digital berbasis online. Dengan meningkatkan pemahaman peserta mengenai pengaplikasian platform digital, diharapkan dapat meningkatkan jumlah pesanan produk UMKM handicraft atau souvenir. Metode pelaksanaan pengabdian pada masyarakat yang digunakan yaitu ceramah dengan porsi sebesar 20 %, pelatihan pembuatan konten platform digital dengan porsi sebesar 40 %, pendampingan kepada pelaku UMKM dengan porsi sebesar 40 %. Melalui langkah-langkah yang meliputi: persiapan, pelaksanaan dan evaluasi untuk melihat peningkatan dan perkembangan para pelaku UMKM sebelum dan sesudah dilakukannya pendampingan.
Inovasi Kemasan Produk Sambal Lingkung sebagai Produk Kuliner Unggulan Khas Jambi
Authors: Solikhin Agus , Hasbullah Husni , Sriayudha Yayuk , Siregar Ade Perdana
Published: February 2025

Konsumen tidak hanya sebatas melihat pada nilai atau fungsi dari suatu produk yang dibutuhkan, tetapi konsumen juga memperhatikan apakah produk yang dipilih memiliki nilai tambah atau kelebihan dibandingkan dengan produk lain yang sejenis. Sambal lingkung adalah sambal kering yang terbuat dari ikan melalui proses sangrai tanpa menggunakan minyak. Produk sambal lingkung ini memiliki potensi untuk dikembangkan sebagai salah satu oleh-oleh khas Jambi karena rasanya yang lezat, gurih dan keberadaanya yang belum ada di daerah lain. Melalui kegiatan ini diupayakan adanya inovasi produk sambal lingkung sebagai upaya peningkatan usaha UMKM, karena sambal lingkung belum memiliki kemasan yang menarik. Pendekatan yang ditawarkan untuk menyelesaikan permasalahan mitra adalah sebagai berikut: 1) Metode ceramah, dengan memberikan materi mengenai trik membuat desain yang menarik; 2) Metode tutorial, dengan membuatkan desain yang menarik untuk kemasan; 3) Metode diskusi, memberikan kesempatan tanya jawab mengenai hal-hal yang belum dipahami atau kendala-kendala yang dihadapi selama kegiatan ini. Pelaksanaan kegiatan pengabdian kepada masyarakat yang dilaksanakan dapat memberikan solusi pada permasalahan yang dihadapi mitra. Penjelasan mengenai desain kemasan dan praktek membuat kemasan dapat dipahami oleh mitra dengan baik. Kemasan yang baik memberikan kepercayaan kepada konsumen bahwa produk higienis, bersih dan rapih. Desain yang menarik memberikan kesan tersendiri bagi konsumen dan akan menumbuhkan minat beli.
Peningkatan Efisiensi dan Produktivitas UMKM di Desa Ture melalui Pelatihan Digital Finance dan Inovasi Bisnis Digital
Authors: Ihsan Moh , Firmansyah Firmansyah , Willian Rohman , Yarni Meri , Adjidirman Adjidirman , Saputra Muhammad Haris
Published: February 2025

Desa Ture terletak di Kecamatan Pemayung, Kabupaten Batanghari, Provinsi Jambi, dimana UMKM di desa ini memiliki masalah pada rendahnya pemahaman tentang teknologi digital dan kurangnya efisiensi dalam pengelolaan bisnis oleh pelaku UMKM. Selain itu juga masalah dalam fungsi manajemen, pemasaran digital yang lemah, serta pengelolaan keuangan yang kurang optimal serta belum ada inovasi pada produk yang dimiliki dan hanya berfokus pada penjualan buah duku, durian yang hanya musiman. Oleh karena itu, kegiatan pengabdian ini memiliki tujuan untuk melakukan pelatihan dan pemberdayaan Digital Finance dan Inovasi Bisnis Digital yang menjadi kunci untuk meningkatkan efisiensi dan produktivitas UMKM di desa Ture. Sehingga UMKM Desa Ture dapat memanfaatkan teknologi digital untuk meningkatkan kinerja operasional, merumuskan strategi bisnis yang lebih efektif, dan meningkatkan daya saing di pasar yang semakin terdigitalisasi. Metode yang digunakan adalah metode ceramah, diskusi/tanyajawab pada pelatihan yang diberikan. Luaran kegiatan ini yaitu Peningkatan Efisiensi dan Produktivitas UMKM di Desa Ture melalui Pelatihan Digital Finance dan Inovasi Bisnis Digital Peningkatan pemahan terkait Digital Finance dan Inovasi Bisnis Digital serta Pemerintah Desa memiliki wawasan terkait dengan regulasi dalam mendorong kinerja UMKM
Reaction of soybean varieties of Amur selection to seeding rate and sowing method
Authors:   Heihe Branch of Heilongjiang Academy of Agricultural Sciences, Ran Wei ,   Far Eastern State Agrarian University, Selikhova Olga A. ,   Far Eastern State Agrarian University
Published: February 2025

Most farms in the Amur region cultivate soybeans using row cropping with row
spacing of 15 cm, which limits the potential of domestic varieties by reducing the feeding area of oneplant. Soybean yield in the region in 2023 averaged 15,9 c/ha while the potential was twice as high.
The study of the reaction of highly productive soybean varieties to elements of agricultural technology is relevant. The article presents research results for 2017–2019 in the conditions of the southern
agricultural zone of the region, according to the influence of seeding rates and sowing method on the
size of soybean varieties, elements of the crop structure and seed yield. The object of the research
was highly productive soybean varieties Lidiya, Persona and Umka, selected by the All-Russian Research Institute of Soybeans. Studies have shown that when cultivating soybeans, in order to obtain
the planned yield, the sowing density should be regulated by the seeding rate and row spacing. A
significant decrease in yield was noted at low seeding rate of 250 thousand units/ha and high seeding
rate of 850 thousand units/ha. Additionally, a significant decrease in yield was noted with row sowing method of 15 cm and wide-row sowing method of 60 cm. More favorable conditions for growth
and formation of potential yield in soybean varieties of Amur selection are formed at a seeding rate
of 550 thousand units/ha (2,42–2,78 t/ha) and 400 thousand units/ha (2,15–2,60 t/ha), as well as row
spacing of 45 cm (2,26–2,70 t/ha) and 30 cm (2,16–2,68 t/ha). Cultivation of the studied soybean
varieties in a row method with low and high seeding rates is not advisable.
Soybean pests in Amur region: distribution and station confinement
Authors:   All-Russian Research Institute of Soybean, Kuzmin Alexander A. , Anisimov Nikolay S. ,   All-Russian Research Institute of Soybean
Published: February 2025

The results of field research from 2019 to 2023 are presented in the given article. The
purpose of the research was to determine the species composition, distribution, density and habitat
attachment of insect populations of soybean pests in Amur region. In the districts of Amur region
cultivating soybeans, 37 species of insects belonging to 20 families from 6 orders have been recorded. Among the registered species, representatives of the order Lepidoptera dominate – 18 species
(48.6%). Maps of the distribution of soybean pest species in the region have been prepared, outbreaks of which were noted during field research: Leguminivora glycinivorella, Pyrrhia umbra and
Heliothis adaucta, as well as the Gryllotalpa orientalis. Mathematical processing of local species
lists according region was carried out using the Jaccard similarity coefficient, as well as additional
verification of calculations using the method of J. Imbrie and N. Kipp. Based on the data obtained,
clustering of the studied territories was carried out according to the composition of the entomofauna.
A high degree of association of insect pests with habitats was revealed. It was found that terrain, phytocenotic and edaphic factors had a greater influence on the density and species composition of pests
than local weather and climatic conditions. Species distributed mainly in the southern regions often
reached the northern border of soybean cultivation along river beds. At the same time, boreal species
were not recorded in soybean agrocenoses in the south of the region. General recommendations are
proposed for pest control and reducing damage from their activity in different soybean cultivation
zones, taking into account local conditions.
Идентификация генов биосинтеза антимикробных пептидов Bacillus pumilus в подавлении Phytophthora spp.
Authors:   Peoples’ Friendship University of Russia named after Patrice Lumumba, Tran Quang Van ,   Vietnam National University of Agriculture, Pakina Elena N. ,   Peoples’ Friendship University of Russia named after Patrice Lumumba, Ha Cuong Viet ,   Vietnam National University of Agriculture
Published: February 2025

Phytophthora species adversely impact citrus growth and health, leading to significant reductions in quality and yield in commercial orchards. Bacillus pumilus, a natural inhabitant of soil, shows potential as a biological control agent for managing Phytophthora. PCR
analysis for antimicrobial peptide genes demonstrated that B. pumilus strains possessed up to
four distinct antibiotic biosynthesis genes: BacA, BmyB, spaS, and ituC, which contributed to the
production of antibiotics including bacilysin, bacillomycin, subtilin, and iturin. This study underscores Bacillus pumilus isolates as effective bacterial biocontrol agents against Phytophthora.
Moreover, applying bacterial suspensions of B. pumilus strains shows promise in alleviating root
rot in citrus seedlings, with observed plant survival rates of 100% and maximal growth promotion particularly notable in plants treated with B. pumilus (VN-K13).