bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-term changes of nitrogen leaching and their contributions to lake eutrophication dynamics on the Yangtze Plain of China
Authors: Guan Qi , Tang Jing , Feng Lian , Olin Stefan , Schurgers Guy
Published: November 2022

Abstract. Over the past half century, drastically increased chemical fertilizer have entered agricultural ecosystems to promote the crop production on the Yangtze Plain, potentially enhancing agricultural nutrient sources for eutrophication in freshwater ecosystems. However, long-term trends of nitrogen dynamics in terrestrial ecosystems and their impacts on eutrophication changes in this region remain poorly studied. Using a process-based ecosystem model, we investigated the temporal and spatial patterns of nitrogen use efficiency (NUE) and nitrogen leaching on the Yangtze Plain from 1979 to 2018. The agricultural NUE for the Yangtze Plain significantly decreased from 50 % in 1979 to 25 % in 2018, with the largest decline of NUE in soybean, rice and rapeseed. Simultaneously, the leached nitrogen from cropland and natural land increased with annual rates of 4.5 kg N ha-1 yr-2 and 0.22 kg N ha-1 yr-2, respectively, leading to an overall increase of nitrogen inputs to the fifty large lakes. We further examined the correlations between terrestrial nutrient sources (i.e., the leached nitrogen, total phosphorus sources, and industrial wastewater discharge) and the satellite-observed probability of eutrophication occurrence (PEO) at an annual scale, and showed that PEO was positively correlated with the changes in terrestrial nutrient sources for most lakes. Agricultural nitrogen and phosphorus sources were found to explain the PEO trends in lakes in the western and central part of Yangtze Plain, and industrial wastewater discharge was associated with the PEO trends in eastern lakes. Our results revealed the importance of terrestrial nutrient sources for long-term changes in eutrophic status over the fifty lakes of the Yangtze Plain. This calls for sustainable nitrogen applications in agriculture systems to improve water quality of local lake ecosystems.
Qualitative and quantitative monitoring of drinking water through the use of a smart electronic tongue
Authors: Arrieta Alvaro A. , Marquez Said , Mendoza Jorge
Published: November 2022

Abstract. The aim of this work was to evaluate a smart electronic tongue device as an alternative for qualitative and quantitative monitoring of drinking water. The smart electronic tongue consisted of a voltametric polypyrrole sensor array, linked with a multi-channel electronic system (multipotentiostat) based on PSoC (programable system on chip) technology controlled by a smartphone with a data acquisition and control app. This device was used in the monitoring of drinking water from the Sincelejo city water supply system; also, water samples collected and analyzed by the public health agency were used. The voltammetric measurements carried out with the smart electronic tongue showed cross-sensitivity of the polypyrrole sensor array, which allowed the discrimination of the samples through of principal component analysis by artificial neural networks. In addition, the voltammetric signals registered with the smart electronic tongue allowed, through partial least square (PLS) by artificial neural networks analysis, estimating the concentrations of some important analytes in the evaluation of the physicochemical quality of drinking water with R2 values higher than 0.70. The results allowed to conclude that the smart electronic tongue can be a valuable analytical tool that allows, in a single measure, to perform qualitative and quantitative chemical analysis (alkalinity, calcium, residual chlorine, chlorides, total hardness, phosphates, magnesium, and sulfates), it is also a fast, portable method that can complement traditional analyzes.
Exploring the transition between water and wind-dominated landscapes in Deep Springs, California as an analog for transitioning landscapes on Mars
Authors: Dorn Taylor , Day Mackenzie
Published: November 2022

Abstract. Many planetary surfaces have been shaped by aeolian and fluvial processes, and understanding the resulting landscape is of critical importance to understanding changes in climate. Surface features on Earth and Mars are commonly observed using a variety of remote sensing methods. The observed geomorphology provides evidence of present- and paleo-processes, but interpretations are limited by the resolution of the data and similarity to well-understood systems on Earth. In this work, we study a complex fluvio-lacustrine and aeolian landscape at Deep Springs playa, California, using field measurements and remote sensing as an analog for a wet-to-dry transitioning landscape on Mars. The playa system in arid Deep Springs reflects fluvio-lacustrine processes in its interior, but transitions to aeolian-dominated processes along the playa margin. Weather station data and field observations collected over 34 months illustrate the interplay between aeolian and lacustrine processes and provide context for interpreting the observed geomorphology in aerial images. Our results showed a consistent distal-to-proximal geomorphic transition in the landscape defined by the changing expression of polygonal fractures, wave ripples, and evaporite deposits. Crescent shaped sedimentary deposits, originally suspected to be related to barchan dunes, proved unrelated to aeolian processes. We discuss the processes, sedimentary features, and climate drivers at Deep Springs to provide a potential framework for identifying and interpreting similar interactions between fluvio‐lacustrine and aeolian geomorphology elsewhere on Earth, on Mars, and beyond.
Data fusion uncertainty-enabled methods to map street-scale hourly NO2 in Barcelona city: a case study with CALIOPE-Urban v1.0
Authors: Criado Alvaro , Mateu Armengol Jan , Petetin Hervé , Rodríguez-Rey Daniel , Benavides Jaime , Guevara Marc , Pérez García-Pando Carlos , Soret Albert , Jorba Oriol
Published: November 2022

Abstract. Comprehensive monitoring of NO2 exceedances is imperative for protecting human health, especially in trafficked urban areas. However, accurate spatial characterization of exceedances is challenging due to the typically low density of air quality monitoring stations and the inherent uncertainties of urban air quality models. We study how observational data from different sources and time scales can be combined with a dispersion air quality model to obtain bias-corrected NO2 hourly maps at the street scale. We present a kriging-based data-fusion workflow that merges a dispersion model output with continuous hourly observations, and uses a machine-learning-based Land Use Regression (LUR) model constrained with past short intensive passive dosimeter campaigns observations. While the hourly observations allow to bias-adjust the temporal variability of the dispersion model, the microscale-LUR model adds information on the NO2 spatial patterns. Our method includes uncertainty calculation based on the estimated error variance of the Universal Kriging technique, which is subsequently used to produce urban maps of probability of exceeding the 200 µg /m3 hourly and the 40 µg /m3 NO2 annual average limits. We assess the statistical performance of this approach in the city of Barcelona for the year 2019. Our results show that simply merging the monitoring stations with the model output already significantly increases the correlation coefficient (r) by +29 % and decreases the Root Mean Square Error (RMSE) by -32 %. When adding the time-invariant LUR model in the data-fusion workflow, the improvement is even more remarkable: +46 % and -48 % for the r and RMSE, respectively. Our work highlights the usefulness of high-resolution spatial information in data-fusion methods to estimate exceedances at the street scale better.
Stratospheric intrusion depth and its effect on surface cyclogenetic forcing: an idealized potential vorticity (PV) inversion experiment
Authors: Barnes Michael A. , Ndarana Thando , Sprenger Michael , Landman Willem A.
Published: November 2022

Abstract. Stratospheric intrusions of high potential vorticity (PV)
air are well-known drivers of cyclonic development throughout the
troposphere. PV anomalies have been well studied with respect to their
effect on surface cyclogenesis. A gap however exists in the scientific
literature describing the effect that stratospheric intrusion depth has on
surface cyclogenetic forcing. Numerical experiments using PV inversion
diagnostics reveal that stratospheric depth is crucial in the intensity of
cyclonic circulation induced at the surface. In an idealized setting,
shallow, high-PV intrusions (above 300 hPa) resulted in a marginal effect on the surface, whilst growing stratospheric depth resulted in enhanced surface
pressure anomalies and surface cyclonic circulation. It is shown that the
height above the surface that intrusions reach is more critical than the
vertical size of the intrusion when inducing cyclonic flow at the surface.
This factor is however constrained by the height of the dynamical tropopause above the surface. The width of the stratospheric intrusion is an additional factor, with broader intrusions resulting in enhanced surface cyclogenetic forcing.
RELATIONSHIP OF SOCIAL MEDIA USE WITH SOCIAL INTERACTION ABILITY IN ADOLESCENT AT YAPIM NAMORAMBE PRIVATE HIGHT SCHOOL
Authors: Tane Reisy , Sembiring Friska Br.
Published: November 2022

In the era of globalization, social media is very often used for daily needs. The use of social media is carried out by teenagers because of their high curiosity about the most up-to-date information quickly. The objective of this study was to determine whether there is a relationship between the use of social media and the ability of social interaction in adolescents at YAPIM Namorambe Private High School. This study uses a quantitative method with a cross-sectional approach. The number of samples used was 73 students with the total sampling method. This research was conducted at YAPIM Namorambe Private High School from April to May 2022. The data analysis used was the chi-square test. The results of the study explain that 67.1% of the total sample are high social media users. Meanwhile, 36.9% of the total sample uses social media normally. In addition, the social interaction of students at SMA Swasta YAPIM Namorambe is classified as good (64.4%), while the category of social interaction is not good at 35.6%. The data were analyzed using the chi-square test with a p-value of 0.001 which indicates that there is a relationship between the use of social media and social interaction skills. For further research, it is expected to examine other factors that influence social interaction and use more complete methods such as interviews and observations.
Understanding African migrants' and refugees' experiences of digital health technologies in south east Queensland, Australia
Authors:   , Coulibaly Souleymane
Published: November 2022

This thesis focuses on the African migrant and refugee community in South East Queensland to investigate how community members use digital technologies for accessing health information. It demonstrates that African community members in Australia access and use digital technologies differently to non-African members of the community. The thesis highlights that an information sharing culture, especially via instant messaging apps such as WhatsApp, prevails in the African community. The thesis also shows that digital technologies, which convey health information and services around the world, are not equally experienced by people and this has implications for health providers and policy makers.
Assessment of knowledge, concerns and support of physicians towards biobanks in Pakistan, and their willingness to donate
Authors: Ahsan Muhammad
Published: November 2022

Biospecimen collection and storage and biobank data have numerous ethical issues. Physicians are key stakeholders because they may contact prospective participants and become biobank users. This research aims to assess Pakistani doctors' views and knowledge regarding biobanking and willingness to donate. A cross-sectional online survey was conducted. 473 doctors completed the questionnaire. Participants had sufficient knowledge of biobanking. Of those, 74.2% heard of the term "Human Genome Project," while 72.5% were familiar with the term. 61.5% showed their willingness to donate biospecimens. Marital status (0.001), faculty (0.001), involvement in research (0.038), blood and tissue testing in recent years (0.420) and demonstrated a significant relationship with willingness to donate. Although 65.8% agreed biobanks should be able to exchange biospecimens with foreign research groupsand, only 49.5% agreed on collaboration with pharmaceutical companies. Although over half of Pakistani doctors heard of biobanking, the presence of biobanks in Pakistan was restricted. They were concerned about marketing, widespread consent and confidentiality. There is a great gap of knowledge and awareness among stakeholders that should encompass several educational initiatives. Community conversations on the problems of marketing and the return of research findings should begin to achieve an agreement.
A Review on Novel Omicron Virus
Authors: Kumar Gaurav , Gautam Girendra Kumar , Kumar Ravi , Singhal Piyush Kumar
Published: November 2022

WHO in a recent study found a Nobel form of coronavirus in November. The variant name is given SAR- COV omicron (B.1.1.529). It is a higher number of mutation 26-32 spike. The first case of omicron was found in South Africa on November 9th. There is no further treatment that are available to cure omicron in recent time according to WHO and south African. South Africa has a higher number of patients in the globe and in the last few days, it spread all over the worldwide. It is significant that the previous vaccine is less effective against the Omicron variant but it protects the patient somewhere in hospitalization and death and is helpful in speed recovery. A few doctors say primary precautions should be taken like wearing mask, wearing PPE kit and using hand sanitiser etc in recent time number of vaccines available in the market but there is no sign it will cure completely but some level of effectiveness against the virus.
Excessive intake of micronutrients in rural population of Uttar Pradesh state
Authors: Kumar Indresh , Gautam Madhulika
Published: November 2022

Overconsumption of certain nutrients is a matter of concern. As has been well documented, excess intake of micronutrients produces adverse effects on body functions. This study aims to assess the micronutrients being consumed in excessive quantity in Uttar Pradesh and to study such data, in which effects of excess intake of micronutrients was published. The rural population of Uttar Pradesh state was selected for the study. Nutrient intakes of the last 24 hours were assessed by the 24 hours dietary recall method. Out of the 14 considered micronutrients, 4 nutrients were being consumed twice the recommended amount, while the remaining 10 were being consumed less than the recommended amount. Nutrients Aadequecy Ratio were calculated to compare the recommended amounts with the actual intake of selected micronutrients, which were 2.02, 2.25, 2.25, and 2.37, respectively, for phosphorus, manganese, magnesium, sodium. Only manganese had crossed the upper tolerable limit (11 mg/day), apart from this other three excess intake micronutrients were being consumed within the upper tolerable limit.
THỰC TRẠNG Ô NHIỄM MỘT SỐ TÁC NHÂN VI SINH VẬT TRONG SỮA VÀ SẢN PHẨM TỪ SỮA CHO TRẺ EM <36 THÁNG TUỔI TẠI VIỆT NAM 2019-2021
Authors: Kiên Nguyễn Xuân , Chuyên Nguyễn Văn , Xuyến Đinh Thị
Published: November 2022

Mục tiêu: Xác định mức độ ô nhiễm một số tác nhân vi sinh vật trong sữa, sản phẩm từ sữa cho trẻdưới 36 tháng, năm 2019-2021.Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang, lấy mẫu và xét nghiệm 4 chỉ tiêu vi sinhvật thường gặp của 1.500 mẫu sữa, sản phẩm từ sữa cho trẻ dưới 36 tháng đang lưu hành tại 6 tỉnh/thành phố lớn. Kết quả được đối chiếu với Quyết định số 46/2007/QĐ-BYT, ngày 19/12/2007 củaBộ trưởng Bộ Y tế.Kết quả: Sữa, sản phẩm từ sữa cho trẻ dưới 36 tháng tuổi có nguy cơ ô nhiễm vi sinh vật nhiều nhấtlà các chất béo từ sữa. Vi sinh vật bị nhiễm nhiều nhất là Listeria monocytogenes. E.coli: 13,33%mẫu Cream dạng lỏng; 11,11% mẫu bơ vượt ngưỡng giới hạn. Staphylococus aureus: 12,22% mẫuCream bột; 5,00% mẫu sữa bột gầy vượt ngưỡng giới hạn cho phép Salmonella: 6,33% mẫu phomat,8,33% mẫu Cream dạng lỏng; 8,88% mẫu bơ, 7,77% mẫu chất béo vượt ngưỡng giới hạn cho phép.Listeria monocytogenes: 5,00% mẫu Whey bột, 5,00% mẫu sữa cô đặc, 3,67% mẫu phomat, 6,67%mẫu bơ, 10,00% mẫu chất béo và 6,00% mẫu sản phẩm sữa lên men vượt ngưỡng giới hạn cho phép.Kết luận: Tình trạng ô nhiễm E.coli, Staphylococus aureus, Salmonella và Listeria monocytogenesvẫn còn xảy ra ở một số loại sữa và sản phẩm từ sữa dành cho trẻ em dưới 36 tháng tuổi, gây nguycơ ngộ độc thực phẩm đối với trẻ em.
UNG THƯ BIỂU MÔ VẢY TUYẾN ỨC - BÁO CÁO CA BỆNH VÀ TỔNG QUAN TÀI LIỆU
Authors: Công Cung Văn
Published: November 2022

Phân loại mô bệnh học (MBH) các khối u tuyến ức 2015, cập nhật 2021 của WHO, các u biểu môtuyến ức được chia thành 3 nhóm lớn: Thymoma/các u tuyến ức lành tính; Thymic carcinoma/ Ungthư tuyến ức; Thymic neuroendocrine/ U tuyến ức thần kinh nội tiết.Ung thư biểu mô tuyến ức (Thymic Carcinoma - TC) chiếm tới 70% các trường hợp u tuyến ức(Thymoma); Trong đó type ung thư biểu mô vảy (Thymic Squamous Cell Carcinoma - TSCC) làrất hiếm gặp, được chẩn đoán dựa vào tiêu chuẩn MBH và hoá mô miễn dịch (HMMD). Bệnh nhânTSCC cũng thường có các triệu chứng lâm sàng đi kèm với hình ảnh khối u trong trung thất: Xâmlấn các cấu trúc trong trung thất thường gặp, bao gồm hội chứng tĩnh mạch chủ trên. Tuy nhiên, cáchội chứng cận u thường gặp trong u tuyến ức (Thymoma) như nhược cơ, bất sản dòng hồng cầu, hạgammaglobulin lại rất hiếm gặp trong TSCC. TSCC có độ ác tính rất cao và hay di căn xa. Tỉ lệ pháthiện di căn xa lên đến 50-65% tại thời điểm chẩn đoán. Các vị trí di căn thường gặp gồm phổi, gan,não và xương. Tiên lượng ung TSCC rất kém với tỉ lệ sống sau 5 năm là 30%. Tuổi trung bình khiđược chẩn đoán là 50.Chúng tôi giới thiệu ca bệnh nhân nam, 70 tuổi, đến khám và điều trị tại Bệnh viện Phổi trung ương,được chẩn đoán TSCC tuyến ức bằng mô bệnh học và hoá mô miễn dịch với phương cách tiếp cậnchẩn chẩn đoán để các đồng nghiệp cùng tham khảo.
TẦM SOÁT BỆNH GLÔCÔM BẰNG CHỤP ẢNH MÀU GAI THỊ VỚI ỨNG DỤNG PHẦN MỀM TRÍ TUỆ NHÂN TẠO EYEDR
Authors: Tiên Phạm Thị Thủy , Tài Hồ Phương Thanh , Hiệp Đỗ Quốc , Lộc Nguyễn Trọng , Sơn Nguyễn Minh
Published: November 2022

Ứng dụng công nghệ mạng nơ-ron tích chập Darknet YOLO phát triển hệ thống trí tuệ nhân tạoEYEDR có thể tầm soát glôcôm bằng hình ảnh đĩa thị tự động.Mục tiêu: Xác định tính giá trị và tin cậy của thuật toán trí tuệ nhân tạo EYEDR trong tầm soát bệnhglôcôm ở người trưởng thành bằng hình ảnh màu đĩa thị.Phương pháp: Nghiên cứu cắt ngang. Chọn lọc 2470 ảnh màu đĩa thị để huấn luyện cho máy họcbằng mạng nơ-ron tích chập Darknet YOLO nhằm xác định hình dạng optic disc và optic cup của đĩathị, từ đó xây dựng thuật toán trí tuệ nhân tạo để phát hiện đĩa thi có glaucoma và non-glaucoma. Sửdụng bộ test gồm 1028 ảnh dùng để đánh giá giá trị của phần mềm AI này dựa vào độ nhạy, độ đặchiệu, diện tích dưới đường cong ROC (AUC), tính khả dĩ đương, tính chính xác và chỉ số đồng thuậnKappa của máy học và bác sĩ đọc kết quả.Kết quả: Diện tích dưới đường cong ROC (AUC) là 0,93 ± 0,01 (0,92 -0,95; CI 95%), với độ nhạy90,3%, độ đặc hiệu 95,06%, tỉ số tiên đoán dương 90,80%, độ chính xác 86,80% và chỉ số đồng thuậnKappa là 0,86.Kết luận: Phần mềm trí tuệ nhân tạo EYEDR ứng dụng công nghệ CNN Darknet YOLO version 3có độ nhạy cao giúp phát hiện tầm soát glôcôm bằng ảnh màu gai thị trong cộng đồng.
RELATIONSHIP BETWEEN NUTRITION KNOWLEDGE AND AEROBIC FITNESS IN YOUNG GYMNASTS
Authors: Gifari Nazhif , Nuzrina Rachmanida , Kuswari Mury , Hutami Nabila Tri , Ghalda Ayu
Published: November 2022

This study aimed to analyze the nutrition knowledge, nutritional status, body composition, nutrient intake and physical fitness of young gymnasts. The study used a cross-sectional design with 20 subjects comprising rhythmic and artistic gymnasts in Raden Inten, Jakarta. Nutritional status and body composition were measured using anthropometric measurements, macronutrient and micronutrient intakes were measured with 3x24-h food recall, physical fitness was measured using the bleep test (20m shuttle run), and nutrition knowledge was assessed using questionnaires consisting of 30 questions on macronutrients, micronutrients and water. The results indicated that the gymnasts (n=20, 13.7±2.1 y.o, 37.8±8.2 kg and 147.3±10 cm) generally had a fairly good nutrition knowledge score (73.2%); i.e. 10 people in the good nutrition-knowledge group and 10 people in the poor nutrition-knowledge group. The majority of the macronutrient and micronutrient intakes were below the nutritional requirements, in both the good and poor nutrition-knowledge groups. The nutrition knowledge scores were low for hydration-related knowledge (66%), while the scores for macronutrient and micronutrient knowledge were 73.8% and 84.2%, respectively. This study found that nutrition knowledge had a positive correlation with physical fitness (p<0.05). A sports nutrition-related education intervention is needed for those gymnasts that still have poor nutrition knowledge. Sports nutrition knowledge needs to be provided for athletes and coaches so that athletes’ intakes meet their nutritional requirements in order to maximise their performance.
Therapeutic Potential of Anupaan: Drug Delivery Vehicle in Ayurveda
Authors: Nitin Pandey , A.K Tripathi
Published: November 2022

Ayurveda isn't always most effective the science of treating the unwell but is the technological know-how of sound and unfeigned dwelling, concept of Anupana is likewise mentioned in each the conditions. Anupana is elucidated together with food (Aahara) in addition to medicines (Aushada) below distinct situations. The speciality of Ayurveda is that the food articles or any medicines can be used for treating different types of diseases by means of changing the Anupana. The numerous styles of Anupana defined in Ayurveda are classified on the premise of Dosha predominance, nature of disease, and administered drugs. The concept of Anupana basically comes into life because of the low efficiency of drugs and palatability. The co-management of Anupana may boom the bioavailability and performance of medications.

Key words: Ayurveda, Anupana, Aahara-Ausadha, Dosha, Vehicle.
A Review on Biofabrication of Zinc Nanoparticles, Its Mechanism and Recent Applications
Authors: Sharma Ravindra Ashok , Chowdhury Mahima Ajay , Sahu Aparna
Published: November 2022

The field of nanotechnology has been one of the major focuses of research for scientists across the world which deals with the production and utilization of nanoscale materials. The increase in popularity of nanotechnology is due to its unique properties which are not present in bulk materials. In these recent years, zinc nanoparticles (Zn NPs) emerged as an important ceramic material that can be utilized across various fields such as medicine, food, textiles, wastewater treatment and many others. The fabrication of Zn NPs can proceed through three major pathways which are physical, chemical and green synthesis. As green synthesis is more environmentally friendly among these methods it is more preferred. Although many reviews on ZnNPs have been published but all of them either focuses on the mechanism, Biosynthesis or its application thus in this review, we summarized various techniques of green synthesis used in fabrication of Zn NPs, its mechanism and its recent applications in various fields reported in past few years.

Key words: Zinc Nanoparticles, Green Synthesis, Biofabrication, Drug Delivery, Biosensors, Bio Imaging
A Comprehensive Review on Revivification for ESRD Patients - Haemodialysis
Authors: R. Nithya , RR Redlin Jani , Reema M.S.
Published: November 2022

Renal system plays a vital role in removing metabolic waste product toxins like urea, uric acid, creatinine from blood and excrete it through urine. Abnormalities in Renal anatomical or in physiological condition can lead to the development of Acute kidney injury, it is reversible but in certain case due to progression of disease condition leads to CKD. Chronic kidney disease (CKD) which is characterized by structural and functional changes of the kidney with glomerular filtration rate of less than 60ml/min/1.73 m. sq. Here, Haemodialysis, extracorporeal procedure to eliminate waste from the body. During this procedure patient may experience various complications such vascular access stenosis, thrombosis of haemodialysis access, thrombus in the dialysis catheter, dialysis access infections, cardiovascular abnormalities, bone disorders, anemia, nutrition deficiency, fluid imbalance, hypotension, The changes in the lifestyle modifications and diet restriction should be maintained by haemodialysis patient to prevent further progression of the disease, complication and to improve the quality of life.

Key words: Kidney, Chronic Kidney Disease, Haemodialysis, End Stage Renal Disease.
Posterior Gastric Perforation: An Uncommon Surgical Emergency
Authors: Hivre Dr. Mangesh , Pawar Dr. Pradeep , Dhaigude Dr. Piyush
Published: November 2022

Posterior perforation of gastric ulcer is a rare clinical condition. The more frequent type of perforation associated with the stomach is an anterior perforation located at the pyloro-duodenal area. Only 5-8% of these ulcers lie along the posterior wall of the body of stomach. Making a pre-operative diagnosis of posterior gastric perforation requires a; high degree of suspicion as most times the diagnosis is made intra-operatively. Delayed presentation is a characteristic of posterior perforation We present a case of a 70-years-old male with a spontaneous posterior gastric perforation with a benign histopathology

Key words: Posterior gastric perforation, gastric ulcer, uncommon surgical emergency.
2-Chloroprocaine Versus Bupivacaine in Spinal Anaesthesia: A Randomized Controlled Study
Authors: Thappa Priya , Jamwal Anju , Kumar Ashwani
Published: November 2022

Introduction: To cope with the increasing day care surgeries, a fast-acting, predictable anesthesia and time-efficient discharge is becoming the need of anesthesiologists. Spinal anesthesia has become popular nowadays in the day care settings due to the advent of new pencil point spinal needles. The study aims to compare 1% 2-Chloroprocaine with 0.5% Bupivacaine in spinal anesthesia with respect to the recovery from anesthesia and time taken to attain discharge readiness criterion.
Methods: Around 100 patients belonging to ASA I and ASA II categories between the age group 18-60 years undergoing surgery with an expected duration of < 60 minutes were selected. Using double-blinded randomization technique, the participants were equally divided into two groups and were given either 1% 2-Chloroprocaine or 0.5% Bupivacaine. The time taken for onset and regression of sensory as well as motor block was noted.
Results: The achievement of the target sensory block was faster with 2-Chloroprocaine (137.20 ± 23.21 mins) than with 0.5% Bupivacaine (270.00 ± 34.10). The mean time to achieve unassisted ambulation in the 2-Chloroprocaine group (179.72 ± 17.30 mins) was less than the Bupivacaine group (256.52 ± 21.98 mins). The discharge readiness criteria was also attained earlier in the 2-CP group (195.98 ± 15.69 mins) than the Bupivacaine group (304.74 ± 16.99 mins). The incidence of postoperative Nausea and Vomiting was seen in 2% of the patients in both groups.
Conclusion: 2-Chlorprocaine is a faster acting drug when compared to Bupivacaine and it helps in faster recovery of the patients undergoing daycare surgeries.

Key words: [2-Chloroprocainae, Bupivacaine, day care surgeries, recovery, spinal anesthesia.]
SEVERITY OF MENTAL ILLNESS AMONG THE INDIVIDUALS DURING 1ST, 2ND AND 3RD WAVE OF COVID-19 PANDEMIC LIVING IN BAHAWALPUR CITY
Authors:   Lahore Garrison University, Lahore Pakistan, Mahreen Iqra , Khan Aqeel Ahmad ,   Department of Applied Psychology, IUB.Pakistan, Shaikh Gul Muhammad ,   Shahida Islam Medical and Dental College Lodhran
Published: November 2022

This current study was carried out to examine the severity of mental illness among the individuals during different waves of covid-19 pandemic. In this connection Depression, Anxiety and Stress Scale (DASS-42) was administered during 1st, 2nd, and 3rd wave of covid-19 pandemic among the individuals living in Bahawalpur City. The total sample of this study was (N=300) individuals living in Bahawalpur City. Out of which (n=100) completed the DASS-42 scale during 1st wave, (n=100) completed during 2nd wave and (n=100) completed during 3rd wave of covid-19 pandemic. The collected data was analyzed by using the SPSS. The results from the collected data revealed that the level of stress was higher among the individuals during 1st and 2nd waves but level of depression and anxiety were higher only during 3rd wave of covid-19 pandemic. The comparison among the gender revealed a higher level of anxiety, stress and depression among female as compared with male. The overall level of depression was higher among married individuals as compared to unmarried individuals. Furthermore, the level of depression was severe among the unemployed individuals as compared with employed individuals. On the basis of the results it concluded that the covid-19 pandemic was not only a medical issue but it was a vicious mental torture for the individuals as well. Hence, the study suggested introducing mental health promoting programs to control the increasing mental health issues among the individuals. Key Words: Stress, anxiety, Depression, COVID-19 Pandemic, 1st, 2nd & 3rd Wave.
Sensory, Proximate and Mineral Composition of Soymilk Made from Intermediate Soy Product
Authors: E.N. Okoronkwo , R.E. Nnam , P.U. Adindu , L.N. Eke
Published: November 2022

This study was an attempt to produce soymilk from an intermediate Soy Product (ISP) to overcome the challenges of the traditional wet milling procedure. Seeds of Soybean (Glycine max) were dry-milled into soybean flour and constituted into soymilk by steeping the milled soybean flour sample into three different periods of SB1, SB2 and SB3 for 1hour, 3hour and 6hours respectively at ambient temperature. The steeped intermediate soy product was then finally processed into soymilk by filtering through a muslin cloth and each filtrate pasteurised at 700c for 30 minutes. The resulting soymilk from this process was then subjected to sensory, proximate and mineral analysis. A soymilk produced using the traditional (wet-milling) method, TPS and a commercial soymilk CBS was used as standard control. The mean values from the analysis were subjected to analysis of variance (ANOVA) at 5% level of significance using SPSS 17.0 for Windows. Significance was established at 95% confidence limit and mean were separated using Duncan test. Considering the organoleptic properties of the samples, sample CBS (commercial control sample) showed a significant difference from the rest of the laboratory samples in all the parameters evaluated (at P<0.05). However, samples SB1, SB2, SB3 and TPS were not significantly different from one another regardless of the processing methods and conditions. The proximate analysis from the soymilk samples showed that the sample steeped for 3hours (SB2) and sample TPS were significantly not different and had the highest values in protein (3.05%), fat (4.05%) and ash (0.50%) than all the other samples at (P<0.05); whereas the sample soaked for 6hours (SB3) was significantly higher in moisture content (84.45%) and Fibre (0.21%) and CBS was significantly higher in carbohydrate (15.67%). The mineral analysis of the soymilk also reviewed that the sample soaked for 3hours (SB2) was significantly higher in calcium (44.45Mg/100g), magnesium (48.86Mg/100g) and iron (1.11Mg/100g), whereas the sample soaked for 1hour (SB1) was significantly higher in zinc and copper (6.54 and 0.24Mg/100g) respectively. This work, therefore, reveals that soymilk of acceptable organoleptic, proximate and mineral qualities can be obtained using the method of an intermediate soy product (ISP).
Cross-Border Trade Policies and Sustainable Economic Development in Nigeria: A Critique
Authors: S. Abubakar , M. Sha’aban
Published: November 2022

The creation of artificial boundaries by colonialist generates desire for cross-border trade as potential instrument for economic integration and development in West Africa. There appears, however, contradictions in states’ policies in Africa which tend to overlook the inviolable boundaries compelling the need for economic interaction across the border for economic development. Paradoxically, neighboring states in Africa, more often than not, capitalize on the trade differences along the border to restrict economic interaction rather than promoting it. Nigeria has recently found itself in the dilemma of either outright trade protection for her economy or liberalizing its trade in the midst of smuggling-induced neighboring countries. Consequently on August 19,2019 President Muhammadu Buhari closed Nigeria's borders with Benin and Niger, declaring that the time had come to end rampant smuggling from those countries. This paper offers a critique of Nigeria’s Border trade policies over the years. The paper intends to challenge the predominant protectionist tendencies among the policy makers in the country. It argued that policy makers in Nigeria should first take measures to refurbish our national economy and then engage all the stakeholders in regional decision making and implementation mechanisms for proper regional trade policies. This will go a long way in providing a framework for intra-regional trade so that the regional environment will encourage more of Nigeria’s trade with its ECOWAS neighbours vis-à-vis sustainable economic growth in the region. If ECOWAS is to succeed in achieving sustainable development in the region, then Nigeria will be the biggest beneficiary; hence, her need to sacrifice more.
INTERVENÇÃO ON-LINE: ANÁLISE DOS EFEITOS NA REGULAÇÃO EMOCIONAL E QUALIDADE DE VIDA DE PROFISSIONAIS DE SAÚDE ATUANTES NA PANDEMIA
Authors: Batista Jéferson Pereira , Da Silva Cintia Ricaele Ferreira , De Araújo Vanda Silva , Araújo Pedro Henrique Souza , Lima Sebastião Elan dos Santos , Gadelha Maria José Nunes
Published: November 2022

INTRODUÇÃO: A crise pandêmica da COVID-19 tem impactado cada vez mais nos aspectos de regulação emocional (RE) de profissionais da assistência, sendo um agravante à saúde mental, po-dendo gerar prejuízos significativos à qualidade de vida (QV). OBJETIVO: Investigar os efeitos da Terapia Cognitivo-comportamental (TCC) nos estados emocionais e na QV de profissionais de saúde que atuaram ou estão atuando nos mais diversos contextos do processo assistencial à saúde em meio a pandemia da COVID-19. MÉTODO: O estudo perpassou três etapas: avaliação pré-intervenção, intervenção e avaliação pós. A amostra foi composta por nove profissionais de saúde das diversas áreas de atuação recrutados entre 2021 a 2022, sendo aplicado um protocolo da TCC grupal de sete sessões. Após aprovação da pesquisa pelo Comitê de Ética e Pesquisa, foram incluídos aqueles que assinaram o Termo de Consentimento Livre e Esclarecido (TCLE). Utilizaram-se na pesquisa: for-mulário sociodemográfico, a Escala de Dificuldades na Regulação Emocional (DERS-16) e Questio-nário de Qualidade de Vida da OMS (WHOQOL-BREF). RESULTADOS: Foram aplicadas estatís-ticas paramétricas comparativas, do tipo t de student, que demonstraram diminuições nos domínios da DERS-16 e aumentos na QV no pós-teste. DISCUSÃO: Os resultados em conjunto com os dis-cursos dos profissionais refletiram o uso de estratégias adaptativas evidenciadas no grupo, como de-senvolvimento de autovalidação emocional, consciência emocional, e mindfulness, demonstrando que os tipos de estratégias para RE no contexto da pandemia são preditores de saúde mental e QV. CON-CLUSÃO: A aplicação do protocolo da TCC voltado para aspectos emocionais apresenta potencial para profissionais de saúde. a intervenção obteve resultados positivos apesar das limitações e dificul-dades quanto ao acesso e adesão dos profissionais de saúde, o que não permitiu uma participação significativa de profissionais que permitisse uma generalização dos resultados.
EFEITO DO MODO DE APLICAÇÃO DO PLASMA ATMOSFÉRICO A FRIO NA CICATRIZAÇÃO DE FERIDAS CUTÂNEAS AGUDAS
Authors: Da Silva Joelma Gomes , Do Amaral Thaynara Ribeiro , De Oliveira Kalyne Danielly Silva , De Oliveira Moacir Franco , Júnior Clodomiro Alves , De Moura Carlos Eduardo Bezerra
Published: November 2022

INTRODUÇÃO: A medicina do plasma tem despontado como uma tecnologia em saúde viável e resolutiva na cicatrização de feridas. OBJETIVO: Comparar o efeito do modo contínuo e pulsado de aplicação do plasma atmosférico frio na cicatrização de feridas cutâneas agudas em porquinhos da índia. MÉTODOS: Foram utilizados 24 animais divididos em quatro grupos e submetidos a realização de 3 feridas no dorso, sendo ao mesmo tempo, experimento e controle segundo aprovação da CEUA (parecer nº 33/2020). Uma ferida foi controle, outra recebeu tratamento no modo contínuo e outra pulsado (10 Hz). O jateamento foi de 1 minuto em cada ferida com gás hélio 2L/ min, imediatamente após a cirurgia e a cada 24 horas por 3 dias consecutivos. Todas as feridas foram fotografadas a partir do dia 0 e analisadas no software Image J. Além do processamento histológico. RESULTADO: A média da taxa de retração das feridas controle nos dias 3, 7, 14 e 21 foi 30,91; 38,5; 89,16; 96,32. Já no grupo contínuo foi de 45,36; 51,95;91,40; 98,13. E no pulsado 54,20; 57,5; 95,74; 99,1, respectivamente. A taxa de retração dos grupos tratados foi significativamente maior que no controle. No dia 7, foi possível visualizar o processo de reepitelização, que se completou no dia 14 nas feridas tratadas com a epiderme e o estrato córneo espessos. No grupo controle, foi possível visualizar isto a partir do dia 14 e a epiderme e o estrato córneo estavam delgados. Não foi mais encontrado tecido de granulação nos tecidos tratados no dia 14, e no controle encontrou-se nos dias 14 e 21. DISCUSSÃO: de maneira geral a literatura aponta para um efeito benéfico do CAP no processo de cicatrização de feridas tanto quantitativamente, como qualitativamente. CONCLUSÃO: O uso do CAP promoveu uma redução do tempo e melhora qualitativa no processo de cicatrização.
EFETIVIDADE DA OZONIOTERAPIA NO TRATAMENTO DA DISFUNÇÃO TEMPOROMANDIBULAR: REVISÃO INTEGRATIVA
Authors: Guimarães Ális Carolina Pordeus , Carvalho João Vitor da Silva , Pereira Igor Figueiredo , Soares Renata de Souza Coelho , Ribeiro Ana Isabella Arruda Meira
Published: November 2022

interagir com compostos orgânicos, tem sido motivo de estudos científicos que tentam elucidar suas propriedades terapêuticas. OBJETIVO: Realizar uma revisão integrativa com objetivo de verificar qual a efetividade da ozonioterapia, enquanto tratamento complementar para a DTM, em artigos publicados até o momento. MÉTODOS: Revisão integrativa envolvendo as bases de dados Bibliografia Brasileira de Odontologia (BBO), Scientific Electronic Library Online (SciELO), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Pubmed (MEDLINE) e Cochrane realizada até agosto de 2022. RESULTADOS: Foram identificadas 81 publicações, e selecionados 9 artigos em conformidade com os critérios de elegibilidade. Os delineamentos mais frequentes dos artigos foram Ensaio Clínico Randomizado com cinco, duas revisões de literatura, uma revisão sistemática e um estudo retrospectivo. Dentre os achados, verificou-se que o uso complementar da ozonioterapia em baixas dosagens melhora dos escores de dor de pacientes com desarranjos internos da ATM e em pacientes com dor muscular mastigatória crônica. No entanto, para o controle da dor causada pela DTM e melhora da função mandibular, pacientes tratados com placa oclusal apresentaram estatisticamente melhores resultados em relação aqueles tratados pela ozonioterapia. Assim como, não sedemonstrou eficaz na redução de sons articulares em pacientes com deslocamento de disco com redução. CONCLUSÃO: A ozonioterapia constituiu-se como uma abordagem terapêutica promissora e alternativa às modalidades de tratamento convencionais. No entanto, são necessários mais estudos com a finalidade de solidificar a concepção de sua eficácia, método de aplicação e a dosagem.
USO DAS TECNOLOGIAS NO MANEJO DA DOR DE PACIENTES COM COVID-19: REVISÃO INTEGRATIVA
Authors: Gomes Lorran Nogueira , Silva Hadassa Dias , Lustosa Aila Samira Palda , Sena Inara Viviane de Oliveira
Published: November 2022

INTRODUÇÃO:A COVID-19 gerou uma pandemia desde 2019 iniciada na China, dada a relevância desse vírus ocorre o relato de dor pelos pacientes adoecidos obtendo assim a necessidade dos profissionais no manejo adequado utilizando dispositivos ou técnicas com o propósito de uma redução da dor significativa.OBJETIVO: Esta revisão integrativa teve como objetivo analisar criticamente a literatura e responder à pergunta “Quais tecnologias em saúde têm sido empregadas a fim de diminuir/tratar a dor em pacientes com covid-19?”. MÉTODOS: A estratégia de busca personalizada foi aplicada nas bases de dados PubMed, Embase e Web of Science. Como critérios de inclusão foram selecionados artigos de pesquisa utilizavam tecnologias em saúde com intuito de melhora da dor em pessoas acometidas por COVID-19 e de exclusão: com uso somente de tratamento convencional, que não utilizavam a população-alvo, com resultados sem o parâmetro dor. A ferramenta de avaliação de estudos nível de evidência (NE) seguiu a Oxford Centre Evidence-Based Medicine que classifica em relação aos tipos de estudo. RESULTADOS: A busca nas bases de dados resultou em 324 artigos, após remoção dos duplicados 243 foram analisados pelo título e resumo de acordo com os critérios de elegibilidade. Destes 29 foram selecionados para leitura na íntegra e 05 incluídos na revisão sistemática por atenderem aos critérios de elegibilidade. CONCLUSÃO: o uso de tecnologias aos sistemas de saúde se tornou uma alternativa para acompanhamento clínico e modernização do serviço.
ASPECTOS CLÍNICOS E CIRÚRGICOS DE HÉRNIAS EM PEQUENOS ANIMAIS – REVISÃO DE LITERATURA
Authors: Silva Maria Júlia de Sousa
Published: November 2022

INTRODUÇÃO: Hérnias são descritas pela literatura como uma ocorrência em que há o deslocamento de um ou mais órgãos de sua posição anatômica normal ocasionado por um defeito ou fraqueza de uma parede corpórea. Trata-se de uma das doenças mais diagnosticadas na rotina cujo tratamento de eleição é a abordagem cirúrgica, sendo o princípio fundamental reposicionar os órgãos herniados, remover tecido redundante e o fechamento das bordas musculares. OBJETIVO: O objetivo dessa revisão foi realizar um apanhado dos últimos estudos publicados a fim de ampliar o conhecimento e contribuir para a atualização dos profissionais da medicina veterinária acerca desse tema considerado relevante para a profissão. MÉTODOS: Os estudos utilizados como fonte de embasamento seu desenvolvimento foram: livros da editora Roca, Elsevier e Saunders, além de periódicos atuais de instituições de ensino brasileiras onde essa temática foi abordada. RESULTADOS: Entre os aspectos relevantes a serem considerados após esse estudo está o fato de que o principal sinal clínico das hérnias em pequenos animais é a tumefação. Entretanto os sinais clínicos podem variar de acordo com o tipo e gravidade da hérnia podendo apresentar tenesmo, constipação, vômitos e dor. Por fim, características como tamanho e a presença ou não de encarceramento são critérios determinantes para a escolha pela intervenção cirúrgica ou não. CONCLUSÃO: Por esse motivo, o aprofundamento no conhecimento clínico e cirúrgico dessa afecção faz-se necessário uma vez que garante aos profissionais maior segurança na tomada de decisões durante as etapas do tratamento. Assim como permite que cada paciente possa ser tratado de forma individualizada refletindo numa maior probabilidade de sobrevida.
Avaliação da qualidade do DNA obtido a partir de material tumoral emblocado em parafina de pacientes com câncer colorretal
Authors: Moura Francisca Ladyssa Lima , De Souza Thuany Pinto Rocha , Da Silva Felipe Souza , Soares Maria Elena Nobre , Fernandes Isabelle Joyce de Lima Silva
Published: November 2022

INTRODUÇÃO: Sabe-se o quão importante são as amostras de DNA para avaliação de tecido tumoral. Tendo em vista que através da sua integridade pode-se ter bons resultados para análises de mutações gênicas. OBJETIVO: Avaliar a qualidade do DNA obtido a partir de material tumoral emblocado em parafina de pacientes com câncer colorretal. MÉTODOS: A população alvo foi composta por 132 pacientes com câncer colorretal admitidos para tratamento oncológico no Hospital Haroldo Juaçaba. O estudo foi realizado no setor de patologia do Hospital Haroldo Juaçaba/Instituto do Câncer do Ceará (HHJ/ICC), onde foram analisadas as informações dos laudos anatomopatológicos, revisão de prontuários físicos e eletrônicos e revisão de lâminas histológicas para demarcação da área tumoral.RESULTADOS: Na seguinte pesquisa ficou evidenciado que dos 132 pacientes identificados como portadores de algum tipo de câncer colorretal, observou-se que foi possível obter DNA viável para análise somente de 56 amostras. CONCLUSÃO: Foi relatado que a absorção de DNA depende do solvente usado. As soluções ácidas representarão a proporção de 260/280 em 0,2 a 0,3, enquanto uma solução básica representará a proporção em 0,3. Portanto, se comparar a proporção 260/280 para diferentes amostras de DNA.
POST EM FORMATO DE HISTÓRIA EM QUADRINHOS ACERCA DA IMPORTÂNCIA DA LIBRAS NO SISTEMA DE SAÚDE
Authors: Sousa Natasha Luísa da Silva , Pereira Maria Karolayne de Araújo , Borges Leonilia Sousa Alencar , Beleza Cinara Maria Feitosa
Published: November 2022

INTRODUÇÃO: Desde o ano de 2002, a Língua Brasileira de Sinais (Libras) é reconhecida e tem evidenciado suas particularidades linguísticas, que devem ser aprendidas para uma melhor comunicação. Diversas pesquisas evidenciam que o surdo possui grandes dificuldades em relação ao uso dos serviços de saúde, caracterizadas, principalmente, pela barreira comunicacional. OBJETIVO: Relatar sobre a produção e publicação de um post interativo no estilo história em quadrinhos, sobre a importância da Libras no sistema de saúde. MÉTODOS: Trata-se de um estudo descritivo do tipo relato de experiência, sobre a criação de um post ilustrativo no formato de História em Quadrinhos (HQ). A confecção da HQ se deu em 5 (cinco) etapas: I – Identificação do tema ou Seleção da temática; II - Busca na literatura; III - Construção do roteiro; IV - Produção do post como uma HQ; V - Publicação e divulgação. RESULTADOS: O post possui 10 lâminas e aborda questões de historicidade dos surdos na sociedade; a importância do conhecimento da língua de sinais, nos serviços à saúde, para o aumento da qualidade da assistência prestada, as especificidades da língua de acordo com as regiões e os preceitos legais envolvidos. Como o post foi feito inspirado na plataforma Netflix, elaborou-se uma lista de filmes e séries para entretenimento do público, baseada em histórias de pessoas surdas para chamar atenção ao tema, e despertar a curiosidade do público para que busquem mais informação. O post alcançou até o presente momento, 35 curtidas, 8 comentários, 5 compartilhamentos e 2 salvamentos, e alcançou 215 contas no Instagram do projeto. CONCLUSÃO: O desenvolvimento da HQ como um post interativo é uma estratégia útil, dado o problema de acesso da população surda aos serviços de saúde.