bluuebunny/crossref_metadata_2025 huggingface dataset:
Cytotoxic and genotoxic assessment of 2-chloropyridine using Allium cepa ana-telophase and comet test
Authors: PİRDAL Güller , LİMAN Recep
Published: April 2019

2-Chloropyridine (2-CPY) is an important precursor of cosmetics, pesticides and other pharmaceutical products and it is also defined as trace chemical in industrial wastewater as the products of the metabolites of agricultural chemical products and river pollutants. In this study, the effects of 2-CPY on mitotic index (MI), mitotic phase frequencies, chromosome aberrations (CAs) and DNA damage in Allium cepa root cells were investigated with Allium ana-telophase and comet assay. Concentrations of 0.5xEC50 (25 ppm), EC50 (50 ppm) and 2xEC50 (100 ppm) of 2-CPY, Methyl methanesulfonate (MMS-10 ppm, positive control) and distilled water (negative control) were applied to A. cepa roots for 24, 48, 72 and 96 h. 2-CPY showed a cytotoxic effect by reducing root growth and MI, but also showed genotoxic effect by increasing CAs (disturbed ana-telophase, chromosome laggards, stickiness, bridges and polyploidy) and DNA damage at substantial levels. The amount of 2-CPY was shown to be increased statistically in both duration and dose by liquid chromatography-tandem mass spectrometry (LC-MS/MS). 2-CPY should be used carefully and investigated its cyto-genotoxic effects with other toxicology test systems.
Improving Efficiency of Underground Heat Storage Systems
Authors: Apel Derek B , Nikbakhdan Babak
Published: April 2019

Underground thermal energy storage (UTES) systems are very popular in Europe and are gaining popularity in North America. The first large-scale solar borehole thermal energy storage (UTES) system in Canada has been implemented in the town of Okotoks (McClenahan D, 2006). The second UTES project in Alberta is located in the community of Southwoods in Edmonton (Kantrowitz T. et al., 2013), which proposes to use natural gas cogenerators to generate electricity and heat during the winter to improve electricity generation efficiency and hence reduce overall energy costs. During the generation of electricity, unused heat can be collected and used to heat space and water for domestic use. During the summer, the electrical output from cogeneration exceeds demand, resulting in a seasonal and annual thermal imbalance which UTES can control through the transfer and storage of the excess heat to a UTES system. Most soils in the Edmonton region consist of sandy clays with high moisture content and high thermo-conductivity. Thus, storing heat in such soils would be inefficient since most of the heat would escape before it could be used for heating purposes. However, if such soils could be modified to become good insulators via innovations in jet grouting and soilcrete technologies, UTES systems could become more prevalent as a renewable energy source in areas with highly thermo-conductive soils. This paper proposes to develop the jet grouting and soilcrete theory and conceptual models required to create an insulated enclosure around UTES systems in highly thermo-conductive soils.
Modelling the Construction On-Site Technology Adoption Process
Authors: Sepasgozar Samad M.E. , Loosemore Martin
Published: April 2019

The global modern technology market in the construction industry is valued at billions of dollars and the approach to technology diffusion taken by vendors has a major impact on the success or failure of those technologies. While many previous studies have examined the adoption and the diffusion of information technologies, the technology diffusion process for advanced on-site equipment such as tower and mobile cranes, piling rig and concrete pumps has received little attention. Based on interviews with vendors and customers covering regions in Australia and North America, during major construction equipment exhibitions, this paper presents a new equipment technology adoption model which, for the first time, describes the relationship between customers and vendors during the on-site technology adoption process. The implications of the model for fostering new on-site technology diffusion to boost productivity are discussed.
Designing for Pre-Fabrication and Assembly in the Construction of UBCäó»s Tall Wood Building
Authors: Fallahi Azadeh , Poirier Erik A. , Staub-French Sheryl , Glatt Javier , Sills Nicholas
Published: April 2019

The construction of a 53 m, 18 story mass timber high-rise on the Vancouver campus of the University of British Columbia poses significant challenges in its design, approval, procurement and construction. As a way to facilitate the project delivery process, the project team called upon extensive use of virtual design and construction (VDC) and building information modelling (BIM) that are supported through a 3rd party VDC service provider. One of the key uses of BIM and VDC in the project is extensive design for pre-fabrication and assembly of mass timber elements and envelope panels as well as mechanical elements. The processes, techniques and tools used to support design for pre-fabrication and assembly on the UBC Tall Wood Building project are presented in this paper. The challenges and lessons learned in the deployment and use of these tools and processes and their impact on project delivery are also discussed. Lastly, the trade-offs and design considerations that support design for pre-fabrication and assembly are examined. Initial findings indicate that the design for pre-fabrication and assembly process is a highly involved and collaborative process which requires the presence of key decision makers up front in the project delivery process. They also indicate that the involvement of a 3rd party BIM and VDC modeller, using highly sophisticated digital tools, is necessary to ensure proper information flow and capture relating to the elements being designed for pre-fabrication and assembly. Ultimately, in the context of mass timber high-rise construction, where competitive advantage over other approaches resides in speed and quality of execution, aesthetic and sustainability concerns notwithstanding, designing for pre-fabrication and assembly is key in ensuring the projectäó»s economic viability.
Recovery time analysis of back muscle fatigue in panelized residential modular construction factory
Authors: Ahn SangJun , Han SangUk , Al-Hussein Mohamed
Published: April 2019

Construction workers in panelized construction factory settings are often exposed to physically demanding and repetitive activities during panel assembly, which requires manual processes. Consequently, these factory workers are often exposed to potential risks, namely work-related musculoskeletal disorders (WMSDs), due to muscle fatigue. Therefore, it is important to evaluate levels of fatigue and provide appropriate interventions to minimize the health risk of workers. Previous studies have shown that sufficient rest could reduce risk of WMSDs from fatigue and is considered one of most practical way to minimize risk. Rest break schedule analysis on workeräó»s fatigue in different industries has been documented; however, to the authoräó»s knowledge, the analysis on panelized construction has not yet been studied. To address this gap, fatigue of workers is estimated using an equation, which was derived mathematically, in terms of recovery time compared with break time schedule. A case study of a panelized construction factory in Edmonton, Alberta, Canada is performed to evaluate the effectiveness of rest break schedules. The results from the case study show that workers at the panelized construction factory require more frequent and longer break time to reduce potential risk of WMSDs.
A BIM-based Supply Chain Integration for Prefabrication and Modularization
Authors: Ocheoha Iloabuchi Alex , Moselhi Osama
Published: April 2019

Prefabrication and modularization helps to reduce cost and schedule time for on-site activities. The use of Building Information Modeling (BIM) helps to improve collaboration and improve the construction process. The improved installation precision provided by BIM Model-Driven Prefabrication can decrease on-site labor time and increase productivity. Prefabrication, Modularization, and off-site construction transfers activities that would have been performed on site to earlier stages of the supply chain. The implementation of Just-In-Time (JIT) delivery transfers the costs and risks associated with inventory to the supplier. Construction Supply Chain Integration can help reduce cost and waste across the supply chain particularly for large and complex buildings. This paper presents a methodology that utilizes a BIM based construction supply chain integration to reduce cost and waste in the construction and offsite manufacturing processes. It utilizes the integration of BIM with the on-site schedule and the manufacturing or fabrication schedule of the different supply chain members. The methodology utilizes the onsite schedule, lead times of prefabricated elements or modules and the transportation logistics to help reduce cost across the supply chain. The information, material and cash flows as well as the transportation logistics is utilized in generating an optimized just-in-time delivery schedule for large and complex buildings. The optimized delivery schedule takes into account the variations in the on-site and off-site schedules to forecast delivery dates of precast elements or fabricated modules.
Towards net zero energy modular housing: a case study
Authors: Hachem-vermette Caroline , Dara Chinyere , Kane Rhys
Published: April 2019

The paper summarizes an investigation of the performance of container based housing units developed by Ladacor Ltd, and compares this performance to traditional housing constructed according to existing standards and codes. The results indicate that the case study housing system can reduce thermal loads (heating and cooling) by about 57% as compared to the same house designed according to the code. Implementing additional efficiency measures and solar design strategies such as increased south window size, suitable shading devices, thermal mass, and more airtight construction, leads to improved performance. This enhanced scenario can reduce the thermal load by 72% as compared to the code scenario and by about 35% as compared to the original case study system. Achieving a net-zero energy status can be reached by integrating photovoltaics on the south roof of the single-family housing designed with Ladacor roof, assuming energy efficient appliances, lighting and domestic hot water. The optimal case can reach a net positive energy status, with a PV system integrated on the south facing roof surface. Results from this investigation can serve in developing innovative design concepts and guidelines for the design of low cost, self-sufficient modular housing.
Construction Capacity and New Housing Demand Caused by Tornados
Authors: Alves Augusto , Arditi David
Published: April 2019

Recent research shows that construction of new houses takes the majority of the recovery time after a tornado. The rapid procurement of new houses depends largely on the existing construction capacity in the region affected. In this study, information about the construction industry in a tornado-prone region is extracted from U.S. economic Census data by using NAICS (North American Industry Classification System) categories. The present capacity of the construction industry is calculated by extracting (1) the inventories of materials and supplies, and (2) the value of new houses put in place in a targeted tornado-prone region, in this study, Oklahoma. A method is proposed to calculate the extra construction capacity in the targeted region using the information extracted from U.S. Census data. The extra construction capacity hence calculated is then compared to the anticipated need for new houses after a severe tornado, calculated by considering the historical records of damages caused by past tornados. The results of the study indicate that the existing construction capacity in the Oklahoma region is not enough to rapidly respond to the anticipated need for new houses after a tornado.
A New Graduate Course on Modular Construction: University of Nevada, Las Vegas
Authors: Choi Jin Ouk
Published: April 2019

Modular construction has been highlighted as one of the key technologies which can significantly improve the construction industry by major professional conferences (i.e., 2017 CII (Construction Industry Institute) Annual Conference, Autodesk University (Las Vegas 2017), CONEXP- CON/AGG) held in 2017. It is now evident that practitioners in the construction industry recognize and pay more attention to the value of modular construction, and consider implementing it. One of the enablers that can accelerate higher levels of modularization across the industry is changing project stakeholdersäó» stick-build paradigm to modularization. However, as most of the engineering schools in the U.S. teach courses based on the stick-build approach, students do not have an opportunity to learn the modular approach. Due to this reason, when they become owners, designer, and contractors, they are captured by the stick-build paradigm and more likely become reluctant to expand their modularization äóěcomfort zones.äóť To accelerate higher levels of modularization and meet the need of students and the industry, the Department of Civil and Environmental Engineering and Construction at the University of Nevada, Las Vegas, led by Dr. Jin Ouk Choi, recently created a new graduate-level course on Modular Construction in 2017 which covers an overall understanding of modular construction concepts including, advantages, disadvantages, impediments, industry status, business case process, execution plans, critical success factors, and standardization strategies of modularization. This paper will introduce the course in terms of its vision, learning objectives, development procedure, structure, contents, and studentsäó» feedback who took the course in Spring 2017.
Prefabrication in the Australian context
Authors: Li Hong Xian , Luther Mark , Mills Anthony
Published: April 2019

Australia actually has a long history with prefabricated building since its early settlement days. However, methods of prefabrication have, until the past decade, been relatively few and almost nonexistent with the exception of relocatable school building or portables. The revival of interest in prefabricated building has been quite recent, involving a few selective construction companies, and the interpretation of prefabrication has mainly resulted in a ‘volumetric’ product as the solution. In response to this, first the paper describes the profile of prefabrication in Australia, and then addresses a pathway for the processes and methods to pre-fabrication based on the identified challenges in Australia. This paper presents these ideas and discusses the up and coming directions of prefabrication in Australia.
Manufacturing of modular buildings: a literature review
Authors: Yang Yi , Pan Wei , Pan Mi
Published: April 2019

The recent decade has seen a growing interest in applying modular construction in high-rise buildings. However, the manufacturing of modular buildings remains slow in making technical progress and the productivity in the factory is low. The production of modules is unique and complicated as it incorporates both manufacturing features and construction trades. Whereas previous studies have proposed technologies and tools associated with design, operation and optimisation of module manufacturing systems, this field of research is currently fragmented. This paper aims to provide a systematic review of existing academic perspectives and suggest future research directions to improve module manufacturing systems. The review explores critical research issues from five aspects: process and activities, organisation and people, factory configuration, technology, and information and control system. Outlined suggestions for research opportunities include (1) increased utilisation of digital manufacturing, (2) more exploration of strategies for the adoption of automated technologies, (3) development of holistic and practical approaches to supporting DfMA methodology, (4) well-defined information management systems through BIM. The findings should contribute to a more comprehensive understanding of the practices, challenges and the state-of-the-art research in the manufacturing of modular buildings.
Comparing cross laminated timber with concrete and steel: a financial analysis of two buildings in Australia
Authors: Cazemier Dylan S.
Published: April 2019

This research paper undertakes a comparative financial analysis of the performance of a Cross Laminated Timber (CLT) apartment building with a concrete and steel apartment building constructed in Australia. A product known as CLT has been found to be an effective alternative form of construction to building with the more traditional materials of concrete and steel. CLT can assist in reducing carbon emissions through carbon sequestration. Respective revenue, time and cost variables are calculated, analysed and compared per development. Financial modelling of these variables results in; Development Margin, Development Profit, Return on Equity (ROE) and Equity Internal Rate of Return (IRR). These figures are performance indicators used to appraise the development. The study supports the economic benefits when comparing CLT to concrete and steel construction. It is concluded that building with CLT may result in less development profit and margin, but an increased Equity IRR due to a reduced investment timeline.
Realisation and Characterisation the BEC for 87Rb Atoms
Authors: AbdulWahhab Nihal A. , Renzoni Ferruccio
Published: April 2019

The Bose-Einstein condensate (BEC) is created in a magnetic trap in the Quadrupole-Ioffe configuration (QUIC). This kind of trap combines an anti-Helmholtz quadrupole field with an offset field produced by a single coil perpendicular to the quadrupole field axis to suppress Majorana transitions. In the quadrupole trap evaporative cooling is performed by using radio frequency, reaching the phase transition to a BEC in the QUIC trap. By using Time of Flight (TOF) technique, the expansion velocity is measured with  and  which lead to temperature of  and  It is roughly around the recoil temperature.
Predicting the Performance of MPI Applications over Different Grid Architectures
Authors: Fanfakh Ahmed Badri Muslim
Published: April 2019

Nowadays, the high speed and accurate optimization algorithms are required. In most of the cases, researchers need a method to predict some criteria with acceptable accuracy to use it after in their algorithms. However, in the field of parallel computing the execution time can be considered the most important criteria. Consequently, this paper presents new execution time prediction model for message passing interface applications execute over numerous grid scenarios. The model has ability to predict the execution time of the message passing applications running over any grid configuration in term of different number of nodes and their computing powers. The experiments are evaluated over SimGrid simulator to simulate the grid configuration scenarios. The results of comparing the real and the predicted execution time show a good accuracy. The average error ratio between the real and the predicted execution time for three benchmarks are 4.36%, 5.79% and 6.81%.
The school attendance problem in Japanese compulsory education: the case of a public junior high school
Authors: Maeda Naoki , Hatada Soichiro
Published: April 2019

The purpose of this study was to collect accurate data on the School Attendance Problem (SAP) in Japan at a local level while using an explicit definition of legitimate attendance. Attendance data on 35 students at a junior high school (M=13.9 years, SD=0.9) were extracted and 11 fundamental factors related to SAP were examined. The analysis showed that the number of absences in the previous year was a strong predictor of SAP in the current year; that more than 90% of the subjects did not take advantage of special institutions; that parents’s attitude was a significant predictor of the prolongation of SAP; and that school withdrawal type (SW) was the most common form of SAP. Regardless of their attendance record or academic performance, all SAP students were advanced to the next grade at the end of the school year. Close cooperation between parents and school is identified as a key factor in addressing SAP. To give effective support to SAP students in Japan, it is necessary to review aspects of the educational system that may be encouraging students not to attend school.
The Influence of Calcination Temperatures in TiO2 Impregnated Ouw’s Natural Clay on Its Degradation Activity of Methylene Blue Dye
Authors: Nature Science
Published: April 2019

The influence of calcination temperatures in TiO2  impregnated Ouw’s natural clay on its degradation activity of methylene blue dye has been done. Calcination process was conducted at various temperatures of 200, 300, and 400 oC. The characterization of TiO2 impregnated clay’s structure was examined by IR analysis. The result showed that Ouw’s natural clay has characterized vibrations of montmorillonite and thermal effect didn’t affect the structure of TiO2 impregnated clay. The highest result of methylene blue’s degradation occurred in the addition of TiO2 impregnated clay calcinated at 200 oC (98.69%). This result was found that calcination temperatures of impregnation process were significantly affect the degradation activity of TiO2­ impregnated clays.
PENGARUH ANALISIS FIXED SAMPLE SIZED SAMPLING, STOP OR GO SAMPLING, DAN DISCOVERY SAMPLING TERHADAP TINGKAT EFEKTIVITAS SISTEM PENGENDALIAN INTERN ATAS AKTIVITAS PEMBUATAN AKTA FIDUSIA DAN WAARMERKING PADA KANTOR NOTARIS DEWI MEUTIA KOTA PROBOLINGGO
Authors: Rustianawati Mutimmah , Dwita Febri Yanti
Published: April 2019

This research aims to determine the level of effectiveness  the company's internal control system if measured by using the analysis of Fixed Sample Sized Sampling, Stop Or Go Sampling, and Discovery Sampling. The subject of this research is Kantor Notaris of DewiMeutiaCiptaNingrum, S.H., M.H., M.Kn which used as research sample. This research data is obtained from direct observation of the transaction evidence that has been selected by using purposive sampling with certain criteria. The analysis technique used is quantitative descriptive technique. The steps of data analysis techniques used in this study is to calculate the effectiveness level of internal control system using Fixed Sample Sized Sampling, calculate the effectiveness of internal control system using Stop Or Go Sampling, and calculate the effectiveness level of internal control system using the Discovery Sampling testing procedure. The result of data processing shows that Internal Control System of DewiMeutiaProbolinggo Notary Office is considered effective.
PENGARUH BUDAYA KERJA DAN IKLIM KERJA TERHADAP DISIPLIN KERJA PEGAWAI KANTOR PERTANAHAN KOTA BOGOR
Authors: Sudarijati . , Puspita Gita
Published: April 2019

Penelitian ini bertujuan untuk mengetahui pengaruh budaya kerja dan iklim kerja terhadap disiplin kerja pegawai Kantor Pertanahan Kota Bogor. Penelitian dilakukan melalui pendekatan secara kualitatif dan kuantitatif. Bentuk penelitian adalah verifikatif meliputi uji validitas, uji reliabilitas dan asumsi klasik analisis regresi linier berganda. Data dikumpulkan melalui kuesioner, observasi, dan wawancara. Metode analisis menggunakan analisis deskriptif, analisis regresi berganda, analisis korelasi, koefisien determinasi, uji F dan uji t. Delapan puluh pegawai diambil sebagai sampel. Hasil penelitian menunjukkan rata-rata tanggapan pegawai terhadap budaya kerja pegawai kuat. Tanggapan pegawai terhadap iklim kerja rata-rata adalah baik. Tanggapan pegawai terhadap disiplin kerja rata-rata tinggi. Secara simultan budaya kerja dan iklim kerja berpengaruh positif dan signifikan terhadap disiplin kerja. Secara parsial menunjukkan bahwa budaya kerja dan iklim kerja berpengaruh positif dan signifikan terhadap disiplin kerja. Kata Kunci : Budaya kerja, iklim kerja, dan disiplin kerja.
PENGARUH MOTIVASI ANGGOTA DAN KOMITMEN ANGGOTA TERHADAP KINERJA ANGGOTA KPRI DI KOTA SUKABUMI
Authors: Gemina Dwi , Hakiki Muhaimin Puji
Published: April 2019

Penelitian ini dilakukan terhadap koperasi berjenis KPRI (Koperasi Pegawai Republik Indonesia). Tujuan dari penelitian ini adalah untuk menganalisis: 1) tanggapan responden terhadap motivasi anggota, komitmen anggota dan kinerja anggota KPRI di Kota Sukabumi, 2) pengaruh secara simultan motivasi anggota dan komitmen anggota terhadap kinerja anggota KPRI di Kota Sukabumi, 3) pengaruh secara parsial motivasi anggota dan komitmen anggota terhadap kinerja anggota KPRI di Kota Sukabumi. Metode yang digunakan dalam penelitian ini adalah deskriptif dan verifikatif. Pengambilan sampel berjumlah 100 anggota KPRI yang diambil dari 31 koperasi aktif berjenis KPRI (Koperasi Pegawai Republik Indonesia) yang telah melaksanakan Rapat Anggota Tahunan (RAT) pada tahun 2017 dan terdaftar di Dinas Koperasi, UKM, Perdagangan, dan Perindustrian (Kopdagrin) Kota Sukabumi dengan menggunakan metode proporsional random sampling. Metode analisis data menggunakan skala likert untuk analisis regresi linier berganda, analisis koefisien korelasi, analisis koefisien determinasi, uji-F dan uji-t. Hasil pengujian menyimpulkan bahwa secara simultan dan parsial variabel motivasi anggota dan komitmen anggota berpengaruh positif dan signifikan terhadap kinerja anggota KPRI di Kota Sukabumi.Kata Kunci: Motivasi Anggota, Komitmen Anggota, Kinerja Anggota Koperasi.
Trifolium patens (Fabaceae), a new species to the flora of the Caucasus
Authors: Mammadyarova K. A. , Asgarov A. M. , Roskov Yu. R.
Published: April 2019

The paper reports the first record of Trifolium patens Schreb. (≡ Сhrysaspis patens (Schreb.) Holub) (Fabaceae) for the flora of Caucasus from the territory of Azerbaĳ an Republic. The plant was collected in 1941 by A. Grossheim, and is stored in the Herbarium BAK. Morphological description of the species and characteristic of its habitat are given.
Allium sarychelekense (Alliaceae), a new species from Kirghizia (Western Tien Shan)
Authors: Krasovskaya L. S.
Published: April 2019

A new species of Allium from Western Tien Shan (Kirghizia) is described, Allium sarychelekense Krassovsk., closely related to A. arkitense R. M. Fritsch. The both taxa are endemic to the eastern part of the Fergana Valley, and are affi liated to the section Acmopetala R. M. Fritsch, subgen. Melanocrommyum (Webb et Berthel.) Rouy.
Fritillaria tunievii (Liliaceae), a new species from Armenia and North-East Anatolia
Authors: Gabrielian E. Tz.
Published: April 2019

The new peculiar species Fritillaria tunievii Gabrielian with twin flowers is described from Urts mountain range in Yerevan fl oristic region of Armenia. Revision of herbarium collections of related species revealed this species to grow also in Aragats, Aparan and Darelegis floristic regions of Armenia, and even in North-East Anatolia. Description, holotype image, distinguishing features from F. hajastanica (Gabrielian) Gabrielian, F. caucasica Adams and F. assyriaca Baker, the map of distribution of the species and photos of plants are enclosed.
Additions to the orchidaceous part of the «Catalogues of the type specimens of the vascular plants» from Central and East Asia, Siberia and the Russian Far East kept in the Herbarium of the Komarov Botanical Institute (LE)
Authors: Efimov P. G.
Published: April 2019

The article represents a description of 23 taxa of orchidaceous plants, which are absent from the «Catalogues of the type specimens of the vascular plants, kept in the Herbarium of the Komarov Botanical Institute» in the sector of Central and East Asia and in the sector of Siberia and the Russian Far East. For one more taxon (Listera savatieri Maxim. ex Kom.), which is mentioned in the published catalogues, we cite missing specimens, which are important for the understanding of this critical taxon. For every name, we give a nomenclatural citation, full data from the herbarium labels of type specimens in LE, and the provenance data from the protologue. The majority of the taxa were described from China and Japan, three taxa were described from Russia, and solitary type specimens originate from North Korea, South Korea. Lectotypes of 2 names are designated: Herminium alaschanicum Maxim., and H. alaschanicum var. tanguticum Maxim.
Genus Corydalis (Fumariaceae) in Yakutia
Authors: Mikhailova M. A.
Published: April 2019

A checklist of 4 species and 2 varieties of Corydalis DC. occurring in Yakutia with a key for their determination is presented. Information on the types of both accepted names and main synonyms, descriptions, details of ecology and distribution in accordance with the administrative division of Yakutia is cited. New data obtained by the author during field research have been taken into account in distribution maps.
TUGAS 2 AUDIT SISTEM INFORMASI SEPTA RIZKYANSYAH
Authors: rizkyansyah Septa
Published: April 2019

Pemanfaatan Teknologi Informasi sebagai pendukung pencapaian tujuan dan sasaran organisasi harus diimbangi dengan keefektifan dan efisiensi pengelolaannya. Maka dari itu, audit TI haruslah dilakukan untuk menjaga keamanan sistem informasi sebagai aset organisasi, untuk mempertahankan integritas informasi yang disimpan dan diolah dan tentu saja untuk meningkatkan keefektifan penggunaan teknologi informasi serta mendukung efisiensi dalam organisasi.
Lost in Translation - Bridging the preclinical and clinical worlds concepts, Examples, Successes, and Failures in Translational Medicine
Authors: Seyhan Attila A
Published: April 2019

The biopharmaceutical companies involved in developing drugs for human diseases are facing considerable challenges, both politically and fiscally. There is growing pressure from the general public, funding agencies, and the policymakers for scientists and industry to improve drug development process, better bridge basic and translational human studies, and ultimately improve the process of the development of more effective, safer, and less costly drugs.The crisis involving the scale of the reproducibility and translatability of preclinical research to human studies and high attrition rate of drug development process is widely recognized both in academia and industry. Despite all this, the high attrition rates of drug development and the magnitude of the reproducibility and translatability problems with the preclinical research findings to human studies remain a fact.Recent reports in literature also suggest that many published research findings in preclinical research are misleading, not as robust as they claim, or cannot be reproduced and hence cannot be translated to human studies. The reasons are complex and challenging. Potential culprits range from the complexity of modern biomedical research to the limitations of tools, the trivial methodological differences, to poor experimental designs, inappropriate data analysis, misuse of statistics, the poor predictability of animal results in humans, as well as training and perverse incentives in academia.There are many reports suggesting solutions to overcome these roadblocks in biomedical research. However, how scientists, researchers, and the biopharmaceutical industry deal with this problem depends on the understanding of the root causes of the problem and the strategies and approaches to solving this problem to improve biomedical research.The purpose of this article is to conduct a thorough literature review to evaluate the nature of some of the problems leading to high attrition rates of drug development and to provide some suggestion to overcome the obstacles that impede the drug development process.
Section 2_DASAR KEBUTUHAN PELAKSANAAN AUDIT SISTEM INFORMASI BAGI ORGANISASI
Authors: khumairah Annisa suci
Published: April 2019

Dalam mendukung aktivitas sebuah organisasi, informasi menjadi bagian yang sangat penting, baik untuk perkembangan organisasi maupun membaca persaingan pasar dan selanjutnya dapat digunakan untuk mengambil langkah strategis dengan tujuan memenangkan persaingan. Sistem Informasi digunakan di segala bidang dalam perusahaan untuk melakukan pemprosesan data menjadi suatu informasi, dan ini merupakan sebuah kegiatan dalam organisasi yang bersifat repetitive, dan agar menghasilkan kualitas informasi yang bermutu, maka harus dilaksanakan secara sistematis dan otomatis.
INTERAL AUDIT 2018 MATAKULIAH AUDIT SISTEM INFORMASI (KS)
Authors: Wahyudi
Published: April 2019

Untuk memberi keyakinan bahha apa yang dilaporkan bawahan tentang perusahaan adalah benar dan dapat dipercaya, maka pimpinan perusahaan membutuhkan adanya internal auditor sebagai pengawasan di dalam perusahaan.Agar dapat tercapainya sistem pengawasan yang baik maka pimpinan perusahaan harus membentuk suatu bidang pengawasan yang dapat bertanggung jawab
Smile (but only deliberately) though your heart is aching: Loneliness is associated with impaired spontaneous smile mimicry
Authors: Arnold Andy
Published: April 2019

As social beings, humans harbor an evolved capacity for loneliness—perceived social isolation. Feelings of loneliness are associated with aberrant affective and social processing, as well as deleterious physiological dysregulation. We investigated how loneliness affects spontaneous facial mimicry (SFM), an interpersonal resonance mechanism involved in social connection and emotional contagion. We used facial electromyography (fEMG) to measure activity of the zygomaticus major (“smiling muscle”) and corrugator supercilii (“frowning muscle”) while participants viewed emotional stimuli, such as video clips of actors expressing anger, fear, sadness, or joy, and emotional IAPS images. We also measured self-reported loneliness, depression, and extraversion levels. Evidence for SFM was found in greater fEMG activity of the zygomaticus and corrugator to positive and negative emotions, respectively. However, individuals reporting higher levels of loneliness lacked SFM for expressions of joy. Loneliness did not affect deliberate mimicry activity to the same expressions, or spontaneous reactions to positive, negative, or neutral IAPS images. Depression and extraversion did not predict any differences in fEMG responses. We argue that impaired automaticity of “smiling back” at another—a faulty interpersonal resonance response—represents a pervasive behavioral mechanism that likely contributes to negative social and emotional consequences of loneliness and may facilitate loneliness contagion.
Finite strain variation across the Mahabharat Thrust in central Nepal Himalaya
Authors: Chamlagain Deepak , Hayashi Daigoro
Published: April 2019

This paper deals with the three-dimensional strain across the Mahabharat Thrust (MT) in the Malekhu area in central Nepal. The MT served as a glide plane for the Kathmandu Nappe. Its footwall is made up of phyllites, quartzites, and amphibolites, whereas the hanging wall contains garnetiferous schists, biotite schists, and quartzites with a few lenses of augen gneiss. A three-dimensional strain analysis reveals that Nadai’s amount of strain intensity (€s ) ranges from 0.396 to 0.575 in the footwall indicating an increasing trend towards the proximity of the MT. In contrast, the hanging wall shows an increase in (€ s) magnitude away from the MT and its value varies between 0.556 (at the basal part) and 0.795 (upper part). Microtextures and structures revealed dynamic recrystallisation of the footwall and static recrystallisation of the hanging wall rocks. The shape of three dimensional strain ellipsoids, types of microstructures, and mechanisms of grainscale deformation indicated that the footwall was dominantly affected by simple shear deformation at lower temperatures while the hanging wall suffered from pure shear with minor sub-simple shear deformation at relatively higher temperatures.
A statistical approach to evaluate the chemistry and quality of groundwater in Jamankira area, Sambalpur district, Orissa, India
Authors: Jena J. K. , Verma P. K. , Sahoo H. K.
Published: April 2019

The groundwater quality in the Jamankira area of Sambalpur district was evaluated to determine its hydrogeochemical variability. A total of thirty groundwater samples were analysed for their major chemical constituents. The quality of groundwater was estimated on the basis of total dissolved solids, sodium adsorption ratio, sodium percentage, residual sodium carbonate, and Piper’s trilinear diagram. Cluster analysis was used in the study as a qualitative means for differentiating the groundwater into distinctive types. The cluster analysis shows: 1) Ca-HCO3-SO4-Mg bearing calcium-rich water and 2) Na - K-Cl bearing sodium-rich water in the study area.
EVALUATING AND COMPARING THE POTENTIAL ENVIRONMENTAL IMPACTS FROM THE PRODUCTION OF DIESL AND LIQUEFIED PETROLEUM GAS, AL-DAURA REFINERY, BAGHDAD, IRAQ
Authors: Ali Alanbari Mohammad , Rahman Ghanem Israa
Published: April 2019

Petroleum is the main source of energy in the world, plays an important role in human life, but also its have many environmental impacts. Various software's are designed to focus on the environmental impacts of Petroleum production and accomplish the assessment, one of these software's is SimaPro software package which is designed to make a valuable contribution. It is an essential tool for analyzing the environmental impact of products during their whole life cycle. A huge amount of knowledge about the environment is built into the program and database, enabling to analyze a product with a minimum of specialized knowledge. In this study, SimaPro7 is used to analyze and evaluate the impacts for AL-Daura refinery for the Diesel and LPG (liquefied petroleum gas) fuel production .The results of LCA are not mostly straightforward in favor of material design over the alternative one. The IMPACT2002+ methodology is used for evaluating the products. This method has proved to be a powerful tool for designers to aggregate LCA results in easily and understandable form. The results of Life Cycle Assessment (LCA) show that Diesel has an impact and damage on the environment (single score) of the order of 0.300302 point for each 1 cubic meter producing from Diesel fuel while LPG has a single score of 0.191243, (The "Single Score" variable is measured in units of points (Pt), which indicates the potential number of people affected by the environmental impacts taken into consideration a period of one year).
THE ANCIENT MYTHOLOGY HEROINE IN VALERY BRUSOV’S RECEPTION
Authors: AREFIEVA NATALIA
Published: April 2019

This article analyzes female characters in ancient mythology in Valery Brusov’s poetic reception. This paper deals with various interpretations of these images and reveals the Dionysian essence of an antique heroine in Brusov’s lyric.
THE MYPHOPOETIC TRADITION IN THE POETRY OF VALERY BRUSOV. MYTHICAL HEROINES AS PERSONIFICATION OF PASSION: ARIADNE AND APHRODITE
Authors: GOZDEK AGNIESZKA
Published: April 2019

This article is devoted to the analysiss of the image of mythical women in the selected poems by Valery Brusov. Based on the examples of Ariadne and Aphrodite we attempt to show that the poet, using mythical female figures, endows them with a new meaning (in his texts this is the essence of personification of passion), subdues them into his poetic perspective. and in this way contradicts the myphopoetic tradition.
"FIVE POEMS BY V.Y.BRUSOV TRANSLATED BY A.CIGAL"
Authors: BEJANYAN KRISTINE
Published: April 2019

"This article deals with the translation of V.Brusov’s five poems from the literary cycle “Dance of Death” in the book “The Dreams of the Mankind”, translated into English by Alex Cigale. Judging by the subtitle the author created them according to the motives of the German artist Hans Golbane J.’s paintings “The images of Death”. The translation first appeared in “Danse Macabre International” magazine. Of course, Brusov is a very distinctive poet but these translations fully reflect all the power of the poet’s intention."
"BRUSOV – EDGAR PO: BETWEEN “INTUITIO” AND “RATIO”"
Authors: KOLCHEVA TATIANA
Published: April 2019

"This article is devoted to the problem of comparative studies of Valery Brusov and Edgar Poe. Reffering to the recently published documents and unknown facts the author gives a new interpretation to the disputed issues of introduction to Brusov Studies."
"BRUSOV’S DEDICATIONS ON BOOKS AND PHOTOGRAPHS: RESULTS AND PROSTECTS OF STUDY"
Authors: MOLODIAKOV VASSILY
Published: April 2019

"This article presents quantative and qualitative analysis of Valery Brusov’s revealed inscriptions on books and photographs both as a biographical and historical source. The author describes their appearance, typical features, the audience and the evolution in the course of time."
VYACHESLAV IVANOV’S LITERARY TRANSLATIONS FOR «THE POETRY OF ARMENIA»: NOTES ON THE HISTORY OF CREATION.
Authors: ALEXANDROVA ELMIRA
Published: April 2019

The present study is devoted to the history of creation of Ivanov’s translations of Armenian authors, involving of all the surviving materials: correspondence between Brusov and Ivanov, other persons’ epistolary materials, the preparatory materials the poet used, the manuscripts of Ivanov’s translations and the line glosses taken from the archive repositories of St.Petersburg, Moscow and Rome.
ARTISTIC SOLUTIONS OF ARMENIAN TRANSLATORS TO THE WORKS OF VALERY BRUSOV'S POETIC CYCLE «IN ARMENIA»
Authors: PETROSYAN MARY
Published: April 2019

The article presents Armenian translations of Valery Brusov’s poetic cycle «In Armenia». Particular attention is paid to the translation of the central poem «To the Armenians», which conveys the views of the Russian poet on the particular historical path of the Armenian people and their national spirit. In comparison with the authentic material, the four translation solutions are analyzed, performed from the 30s to the 80s of the 20th century. The article gives the value judgment of the poems «To Armenia», «To Ararat», «Tigran the Great». On the basis of the analyzed material the author of the article comes to the conclusion that a considerable part of the poems in poetic cycle should be translated anew. The comments and remarks should be considered in the new publication of Brusov's poetry in Armenian.
THE TRANSLATIONS BY ELLIS, A. GLOBA AND S. GOLOVACHEVSKY FOR THE ANTHOLOGY «THE POETRY OF ARMENIA»
Authors: SARAFYAN DIANA
Published: April 2019

The article refers to the analysis of the translations of verses by R. Patkanyan, I.Ioannisyan and Sipil in the anthology «The Poetry of Armenia». The above-mentioned verses were translated by Ellis, A.Globa and S.Golovachevsky. The author of the article made an attempt to reveal whether the translators had managed to preserve the Armenian national spirit and the emotional mood of the originals.
A. IZMAYLOV AND V. BRUSOV (ON THE BASIS OF ARCHIVAL MATERIALS)
Authors: ALEXANDROVA ELMIRA , ALEXANDROV ALEXANDER
Published: April 2019

This article is based on the correspondence between Izmajlov and Brusov (1909-1917) to be published by the Russian Literature Institute (Pushkinskiy Dom) of the Russian Academy of Sciences. The unpublished materials from the archives of St. Petersburg and Moscow were also considered
GENRE-FORMING FUNCTION OF SOCIO-POLITICAL CONFLICT IN SCIENCE FICTION DRAMAS WRITTEN BY BRUSOV IN 1920S
Authors: STRASHKOVA OLGA
Published: April 2019

In Brusov’s dramas of the post-October period the revolutionary epoch is reflected with varying degrees of relevance of its presentation. The dramatic sketch «Pythagoreans» and a drama «The World of Seven Generations» recreate some principles of the governance under the laws of the community «democracy» in the genre of the science-fiction drama. We refer the tragedy «The Dictator», where the conflict is built on the futurological anticipation of the consequences of the proletarian dictatorship, based on the principles of the democratic centralism, to the genre form of the drama dystopia.
V. BRUSOV’S METRIC EXPERIMENTS
Authors: TADEVOSYAN ANAHIT
Published: April 2019

Brusov’s metric experiments are underestimated and understudied. P. Rudnev separately studied Brusov’s metric repertoire and compared it with the works of other authors; however, in his articles, the data have been presented statistically. Besides, the inclusion of the given examples in the relevant sections is controversial in some cases. A metric reference on Brusov’s poetry and substantive analysis of his metric experiments are presented in the article.
V. BRUSOV AND M. SCHICK IN THE CULTURAL AND HISTORICAL CONTEXT OF THE EPOCHE
Authors: GRIGORYAN AROUSYAK
Published: April 2019

The article is devoted to the analysis of V. Brusov’s translation of «Bilder aus vergessenen Tagen» poem by Maximilian Schick. The author of the article estimates the semantic, syntactic and grammatical resemblance, as well as differences between the original and the translation in the cultural and historical context of the age.
TRANSLATIONS OF FRENCH SYMBOLIST POETS (CH.BAUDELAIRE, A.RIMBAUD) BY V. BRUSOV
Authors: HOVHANNISYAN KARINA
Published: April 2019

The article considers the translations of French poetry (Ch. Baudelaire, A. Rimbaud) made by V. Brusov and by other masters of the Russian poetic translation in different periods.
ON THE HISTORY OF PERFORMANCES OF «THE FIERY ANGEL» OPERA (V. BRUSOV – S. PROKOFYEV)
Authors: SARAFYAN DIANA
Published: April 2019

The author of the article tells about some episodes referring to the performances of «The Fiery Angel» – Sergey Prokofyev’s opera. The opera was first staged only after the composer’s death and at first drew the attention of the Western conductors and directors. It is noteworthy that the modern directors tend to modernize the opera’s plot.
DAILY RECORDS AND AN UNFINISHED NOVEL BY V. BRUSOV
Authors: AVANESOVA AREVIK
Published: April 2019

Unpublished Heritage
UNCHARTED NOTES MADE BY V. BRUSOV AS A GYMNASIUM STUDENT
Authors: CHULYAN ANNA
Published: April 2019

Unpublished Heritage
ALEXANDER MANUYLOV’S LETTERS TO V. BRUSOV
Authors: DANIEYLAN ELMIRA
Published: April 2019

Unpublished Heritage
PERSONIFYING METAPHORS AND SIMILES IN V. BRUSOV’S POETRY
Authors: PETROVA ZOYA
Published: April 2019

The paper provides a semantic classification of tenors and vehicles of personifying tropes by V. Brusov. The author analyzes the ways of renewing the traditional tropes by the poet and emphasizes the relevance of personification in V. Brusov’s poetry with semantic dominants of his typical idiostyle.
V. BRUSOV AND HIS INFLUENCE ON B. SADOVSKY’S LITERARY ATTAINMENT
Authors: YELISEENKO ANNA
Published: April 2019

The paper considers the influence of V. Brusov’s literary activities and personality on B. Sadovskoy’s worldview, who was early XX century writer, poet and critic. The author attempts to analyze the reasons for B. Sadovskoy and V. Brusov controversy concerning the publication of «Ozim» (1915), a collection of articles by B. Sadovskoy.
V. BRUSOV’S POETRY IN THE MUSIC OF THE SILVER AGE COMPOSERS
Authors: SARAFYAN DIANA
Published: April 2019

The paper deals with romances, songs and an opera created by prominent representatives of Russian Silver Age music for poems, a novel and translations by V. Brusov. The information concerning the composers and the works by the poet is provided. The author concludes that cultural fusion is typical for the late XIX-early XX century, the epoch of «new culture», based on synthesis and syncretism. Music, poetry, art went hand in hand, to brighten up the world of fiction with vivid colors.