bluuebunny/crossref_metadata_2025 huggingface dataset:
Alexithymia, resilience and paranormal beliefs in an elderly
institutionalized center
Authors: Méndez Inmaculada , García-Sevilla Julia , Martínez Juan P. , Bermúdez Ana Mª , Pérez Pilar , García-Munuera Isabel
Published: April 2021

Alexithymia refers to the difficulty to understand and identify feelings
and those of others. The process of adapting a residential facility is one
of the stressful situations older people may face. In order to overcome this
situation, resilience is critical and even there are people who seek support
in religion or paranormal beliefs. In this paper, we studied the
relationship between alexithymia, resilience and paranormal beliefs in a
group of 35 seniors (21 women) aged between 66 and 95 years old in an
institutionalized center. The instruments used were the TAS-20 Scale in
order to assess alexithymia, the CD-RISC for evaluating resilience and the
Enhanced Paranormal Beliefs Scale. Among main findings, it must be
emphasized that subjects with greater difficulty identifying feelings are
those with less personal control and less belief about extraordinary life
forms; subjects with greater personal control had higher belief about those
extraordinary life forms. Professional applications that can be launched in
elderly institutionalized centers are discussed.
Analysis of knowledge on drug delivery
Authors: Carmona Juan M. , Baena Ana M. , Berral Ana C. , Sotelo Quintiliano , Recio Beatriz , Recio Irene
Published: April 2021

The objective of this study was to determine the knowledge of health
professionals Hospital of Montilla on the administration of drugs in
emergencies. Material: cross-sectional descriptive study conducted at the
Hospital of Montilla (Córdoba). A questionnaire to doctors and nurses were
distributed by random sampling during the month of December 2014. A survey
of Machado de Azevedo et al. (2012) that consists of 9 items for the
assessment of knowledge on medication administration was used. Results: The
sample was composed of 59.1% of physicians and 40.9% of nurses with an
average age of 38.05 (SD±8.981). Regarding the situation of respondents,
72.7% had received prior training. Regarding their own self-assessment,
72.7% considered to have a satisfactory knowledge of drug administration.
90.9% of respondents known to exist protocols on the administration of drugs
in his unit. Discussion: Although the knowledge of drug delivery is
acceptable for health workers, there are differences between the two
analyzed collectives. Therefore, it would be ideal to perform adequate
training and retraining of staff for optimal knowledge and, in this way,
improve health care.
Instruments for evaluating the burden of family caregivers of persons
with dementia
Authors: Martos África , Cardila Fernando , Barragán Ana B. , del Carmen Pérez-Fuentes Mª , del Mar Molero Mª , Gázquez José J.
Published: April 2021

The aging population in developing countries is a reality which has
given rise to degenerative diseases, among them dementia. The changes
undergone during dementia cause a loss of functions which makes the person
affected more dependent on others in performing their activities, and
therefore these activities are taken over by the caregiver. The process of
becoming a caretaker often means the appearance of overload, referring to
the perception that the caregiver has of the influence that caring for that
person has on their health, social and personal life and economy.
Quantification of the risk of exhaustion should be done using a common
procedure. Therefore, this study was intended to review instruments for
evaluating the burden on family caregivers of persons with dementia. The
method used was systematic review of the Lilacs, ProQuest, PsycArticles and
Dialnet Plus databases, after which the primary sources of the instruments
used in those studies were found. Six different versions of four different
instruments were found in this way. In 34 of 42 studies, the burden
evaluation instrument used was the Zarit scale (Zarit Caregiver Burden
Interview) or a version or adaptation of it. These results show that the
preference for this scale for evaluating burden in caregivers is continuous
and without variation since the nineties.
Psychometric properties of the Spanish version of the Temporal
Satisfaction with Life Scale (TSLS): A study on elderly attending to
university programs
Authors: Galiana Laura , Gutiérrez Melchor , Sancho Patricia , Oliver Amparo , Tomás José M.
Published: April 2021

Several measures have been developed for the operalization of
well-being, standing out the Satisfaction With Life Scale (SWLS). To cope
with some of its problems the Temporal Satisfaction with Life Scale (TSLS)
was developed. The aim of this study is to present and validate the Spanish
version of the TSLS, in a sample elderly attending to University programs.
The sample was composed of 737 elderly. Together with the TSLS, an indicator
of general life satisfaction and the SF-8 Health Scale were used. Analyses
included the study of factorial validity, estimations of reliability and
external validity. Results of the confirmatory factor analysis were
adequate: χ2(87)=454.593 (p<.001), CFI=.973; RMSEA=.085, showing
appropriate fit for the three-dimension model posed. Internal consistency of
the three dimensions was high: alpha values of .83 for past, .81 for
present, and .86 for future life satisfaction. Additionally, results of
external validity were as expected. The TSLS addresses the temporal axis in
the measurement of life satisfaction, with psychometric guarantees. Its
utilities are explained in the discussion.
Spanish adaptation of the Alcohol Expectancy-Adolescent Questionnaire,
Brief
Authors: Gázquez José J. , del Carmen Pérez-Fuentes Mª , del Mar Molero Mª , Martos África , Cardila Fernando , Barragán Ana B. , Carrión José J. , Garzón Anabella , Mercader Isabel
Published: April 2021

Alcohol is a substance commonly used by adolescents. Due to the relevant
role alcohol expectancies have for understanding adolescent use behavior,
valid and reliable instruments need to be designed to evaluate these
beliefs. The purpose of this study was to validate the Spanish version of
the Alcohol Expectancy Questionnaire-Adolescent, Brief (AEQ-AB). The sample
was comprised of 315 adolescents aged 14 to 18 years who filled in an ad hoc
questionnaire on demographic data the Spanish version of the EQ and the
(AEQ-AB). Factor analysis showed that the original seven-item model
clustered in two factors (positive and negative), fit the Spanish sample
correctly. The reliability and validity analysis showed adequate translation
and adaptation of the AEQ-AB questionnaire in Spanish adolescents.
Attitudes towards math in primary school students: Differences depending
on the grade and gender
Authors: Valle Antonio , Regueiro Bibiana , Piñeiro Isabel , Sánchez Benigno , Freire Carlos , Ferradás Mar
Published: April 2021

The main aim of this study is to check whether there are differences in
some variables related to attitudes towards math in primary school students
according to the course and gender. The sample consists of 897 students of
the fifth and sixth year of primary education (50.2% boys and 49.8% girls).
The results indicate that the boys, compared to girls, have a higher
perceived competence in math, they are more intrinsically motivated
extrinsic and exhibit lower levels of anxiety. As for the differences in
terms of this variable, the results indicate that students in grade 5 have a
higher perceived competence for math, perceive most useful, are more
intrinsically motivated to this subject and show anxiety levels and some
negative feelings toward the lower than grade 6. Therefore, girls show a
"profile" of less adaptive than men conditions, both in terms of their
perceived competition as their motivation towards math and also in terms of
the emotions associated with this matter. As for the differences depending
on the course, students from grade 5 are those with a much more positive
attitudinal and motivational conditions than grade 6.
The efficacy of expressive writing intervention: the role of optimism and
alexithymia
Authors: del Pino Tasmania , Peñate Wenceslao , Fumero Ascensión , Bethencourt Juan Manuel , Zambrano Sonia
Published: April 2021

The beneficial effects on the health of the re-experimentation of
traumatic experiences are well-established. The effectiveness of using
reexperimentation seems to be affected by certain conditions. Among personal
variables that have been shown to influence the recovery of such experiences
it has highlighted the optimism and alexithymia. The aim of this study was
to evaluate the effects on mental health of an intervention based on
re-experimentation. The sample consisted in a total of 60 participants, of
which 40 carried out a process of emotional re-experimentation through three
sessions of expressive writing. The rest formed the control group. All
participants were evaluated before and after the emotional disclosure in
positive and negative affect, anxiety, depression, intrusive thoughts and
cognitive avoidance. Furthermore, the level of optimism and alexithymia were
controlled. The results showed the effectiveness of expressive writing on
the positive and negative affect and on depression. Among the covariables,
only optimism affected significantly to effect emotional variables. The
contextual and personal conditions that can be ameliorated the clinical use
of emotional disclosure were discussed.
Socially prescribed perfectionism and affectivity in Spanish child
population
Authors: Vicent María , Inglés Cándido , Sanmartín Ricardo , Gonzálvez Carolina , Granados Alós Lucía , García-Fernández José Manuel
Published: April 2021

This study aims to analyze the relationship between Socially Prescribed
Perfectionism (SPP) and affect during childhood. A sample of 804 students
aged between 8 and 11 years old (M=9.57; SD=1.12), as well as the SPP
subscale of the Child and Adolescent Perfectionism Scale and the 10-Item
Positive and Negative Affect Schedule for Children, which assess the
Positive Affect (PA) and Negative Affect (NA), were employed. The mean
scores in PA and NA between students with high and low levels of SPP were
compared. Students with high SPP significantly scored higher than their
peers with low SPP, both in PA and NA. The effect magnitude of the found
differences was small. Accordingly, the results of the logistic regression
analysis revealed that both affective dimensions predicted positively and
significantly high scores in SPP with Odd Ratio values of 1.08 and 1.05,
respectively, for PA and NA. The results do not match the previous empirical
evidence in adult and adolescent population. This implies that the
consequences of considering the environment as demanding of perfectionism
does not have the same consequences in childhood than in later
ages.
Effect size and meta-analysis in Spanish professional
psychologists
Authors: Badenes-Ribera Laura , Frías-Navarro Dolores , Bonilla-Campos Amparo
Published: April 2021

The Evidence-Based Practice approach is based on the use of scientific
research in decision-making in an effort to produce the best possible
services in clinical practice. The knowledge level about effect size
statistics and meta-analysis studies may affect the decision soft
professionals and jeopardize the quality of psychological interventions.
This paper presents the result so fan on-line survey on the degree of
knowledge of these topics among Spanish practitioner psychologists. The
sample consisted of 77 participants (68.8% women and 31.2% men), with a mean
age of 41.44 years (SD=9.42), with age range of 25-64 years. The results
suggest that most of the psychologists survey eddid not have adequate
knowledge about effect size index, meta-analysis studies, or methodological
quality checklists. It is therefore necessary to improve the statistical
education of practitioner psychologists, which might also contribute to
their provement of professional practice.
Gender-specific patterns and determinants of spillover between work and family: The role of partner support in dual-earner couples
Authors: Ayhan Adams  , Katrin Golsch
Published: April 2021

Objective: The study investigates how partner support affects different types of work-to-family and family-to-work conflicts in dual-earner couples divided by gender and parenthood.

Background: In Germany, as in other Western Countries, interrole conflicts between work and family increase, especially within dual-earner couples. Only few studies focused on the effects of partner support on different types of these conflicts.

Method: We use longitudinal data deriving from waves 6 to 10 of the German Family Panel (pairfam) to uncover the extent to which the perception of having a supportive partner reduces time- and strain-based work-to-family and family-to-work conflicts. We conduct longitudinal structural equation models based on information of 1,252 persons, which are full-time employed and live in a dual-earner relationship.

Results: Whereas for men partner support helps reduce stress-based work-to-family conflicts, for women perceived partner support is not beneﬁcial. Within a subsample of parents, the experience of work-to-family conflicts is likely irrespective of partner support. Overall, women’s family-to-work conflicts appear to be reduced by their partners’ support whereas for men this detrimental effect only applies in the case of stress-based family-to-work conflicts.

Conclusion: To sum up the findings, the differences for men and women in the effect of partner support on different types of interrole conflicts indicate a still existing impact of traditional gender norms that connect femininity to house work and masculinity to employed work.
Pregabalin, a GABA Analogue Protects against Carbon Tetrachloride-Induced Oxidative Stress and Liver Injury in Rats
Authors: Abdel-Salam Omar M.E. , Youness Eman R. , Morsy Fatma A. , Sleem Amany Ameen
Published: April 2021

Pregabalin is a synthetic analogue of the neurotransmitter g-aminobutyric acid (GABA) and is used in the treatment of epilepsy and neuropathic pain. The aim of this study was to investigate the effect of pregabalin on toxic liver injury caused by the acute administration of carbon tetrachloride (CCl4). Rats were orally treated with CCl4 for two successive days either alone or along with intraperitoneal pregabalin at doses of 7 and 14 mg/kg. The control group received the vehicle (olive oil). Liver oxidative stress and damage were assessed by determining serum and/or liver tissue levels of malondialdehyde (MDA), nitric oxide (NO), reduced glutathione (GSH), DNA fragmentation, serum aminotransferases, paraoxonase-1 (PON-1), and hepatic histopathology. Results showed that CCl4 significantly (i) increased MDA and NO and decreased PON-1 in both serum and liver tissue, and (ii) decreased liver GSH content and induced marked hepatic DNA fragmentation. CCl4 treatment caused liver tissue injury as evidenced by significantly increased serum aminotransferases. In line with the above biochemical changes, the liver of CCl4-treated rats exhibited massive steatosis, vacuolar degeneration, cloudy swelling, and necrosis. In CCl4-treated rats, pregabalin given at the dose of 14 mg/kg significantly reduced the increments in MDA, NO, serum aminotransferases, and hepatic DNA fragmentation. Liver GSH was unaltered but hepatic and serum PON-1 activity increased after administering pregabalin which also improved, though not normalized, liver tissue histopathology. Collectively, these results suggest that the administration of pregabalin is associated with a reduction in experimental liver injury caused by CCl4.
(First online: Apr 12, 2021)
Four Flavan-3-ol Compounds From The Stembark of Chisocheton balansae C.DC. (MELIACEAE)
Authors: Supratman Unang , Fajar Mohamad , Salam Supriatno , Maharani Rani , Harneti Desi , Nurlelasari Nur;lelasari , Katja Dewa Gede , Safari Agus , Azmi Mohamad Nurul
Published: April 2021

Chisocheton balansae C.DC., is one of the Meliaceae family plants which is the endemic plants from Soputan Mountain, North Sulawesi, Indonesia. This study was aimed to determine the chemical structure of flavan-3-ol compounds from ethyl acetate extract of C. balansae C.DC stembark. Dried powder of C. balansae C.DC stem bark was extracted consecutively with n-hexane, ethyl acetate, and methanol solvents. Four flavan-3-ol compounds, named catechin (1), epicatechin (2), epigallocatechin-3-O-gallate (3), and epicatechin-3-O-gallate (4) were successfully isolated from ethyl acetate extract. The chemical structure of these isolates was determined by spectroscopic methods (1H-NMR, 13C-NMR, DEPT, and 2D-NMR) and comparison with previous reported spectral data. These compounds are first time reported from this plant.
Characterization of Antioxidant Compound from Syzygium polyanthum Leaves Fraction Using UHPLC-HRMS
Authors: Syabana Muhammad Ana , Yuliana Nancy Dewi , Batubara Irmanida , Fardiaz Dedi
Published: April 2021

The leaves of Syzygium polyanthum is widely used in Indonesia as a spice. It has been reported to have significant antioxidant activity. However, the reports on compounds responsible for the activity are very scarce. The purpose of this research was to characterize the chemical profile of S. polyanthumfractions which showed the highest antioxidant activity. The dried leaves of S. polyanthum were fractionated using the different combination of non-polar to polar solvent, those are n-hexane, acetone, water. Fourteen fractions were collected and analyzed for their DPPH antioxidant activity. The chemical profile of selected fractions was characterized using UHPLC-HRMS to identify compounds that might associate with the antioxidant activity of S. polyanthum. The results showed that at the dose of 500 μg/ml, four fractions showed the highest antioxidant activity with the following order: F9 (acetone:water=80:20), F10 (acetone:water=60:40), F1 (hexane 100%) andF3 (hexane:aceton=80:20). UHPLC-HRMSanalysis successfully identified several compounds in F9 and F10. Gallic acid, pyrogallol, and myricetin were identified in F9.  Aconitic acid was identified in F10. All of the identified compounds were previously reported to have antioxidant activity
Backmatter (Instruction for author and back cover)
Authors: Fatoni Amin
Published: April 2021

Backmatter (Instruction for author and back cover)
Benchmarking of Machine Learning Models to Assist the Prognosis of Tuberculosis
Authors: Lino Ferreira da Silva Barros Maicon Herverton , Oliveira Alves Geovanne , Morais Florêncio Souza Lubnnia , da Silva Rocha Élisson , Lorenzato de Oliveira João Fausto , Lynn Theo , Sampaio Vanderson , Endo Patricia Takako
Published: April 2021

Tuberculosis (TB) is an airborne infectious disease caused by organisms in the Mycobacterium tuberculosis (Mtb) complex. In many low and middle-income countries, TB remains a major cause of morbidity and mortality. Once a patient has been diagnosed with TB, it is critical that healthcare workers make the most appropriate treatment decision given the individual conditions of the patient and the likely course of the disease based on medical experience. Depending on the prognosis, delayed or inappropriate treatment can result in unsatisfactory results including the exacerbation of clinical symptoms, poor quality of life, and increased risk of death. This work benchmarks machine learning models to aid TB prognosis using a Brazilian health database of confirmed cases and deaths related to TB in the State of Amazonas. The goal is to predict the probability of death by TB thus aiding the prognosis of TB and associated treatment decision making process. In its original form, the data set comprised 36,228 records and 130 fields but suffered from missing, incomplete, or incorrect data. Following data cleaning and preprocessing, a revised data set was generated comprising 24,015 records and 38 fields, including 22,876 reported cured TB patients and 1,139 deaths by TB. To explore how the data imbalance impacts model performance, two controlled experiments were designed using (1) imbalanced and (2) balanced data sets. The best result is achieved by the Gradient Boosting (GB) model using the balanced data set to predict TB-mortality, and the ensemble model composed by the Random Forest (RF), GB and Multi-layer Perceptron (MLP) models is the best model to predict the cure class.
Dysregulated Metabolites Serve as Novel Biomarkers for Metabolic Diseases Caused by Vaping and Cigarette Smoking
Authors: Wang Qixin , Ji Xianming , Rahman Irfan
Published: April 2021

Metabolites are essential intermediate products in metabolism, and metabolism dysregulation indicates different types of diseases. Previous studies have shown that cigarette smoke dysregulated metabolites; however, limited information is available with electronic cigarette (E-cig) vaping. We hypothesized that E-cig vaping and cigarette smoking altered systemic metabolites, and we propose to understand the specific metabolic signature between E-cig users and cigarette smokers. Plasma from non-smoker controls, cigarette smokers, and e-cig users were collected, and metabolites were identified by UPLC–MS (Ultraperformance liquid chromatography-mass spectrometer). Nicotine degradation was activated by e-cig vaping and cigarette smoking with increased concentrations of cotinine, cotinine N-oxide, (S)-nicotine, and (R)-6-hydroxynicotine. Additionly, we found significant decreased concentrations in metabolites associated with tricarboxylic acid (TCA) cycle pathways in e-cig users verses cigarette smokers, such as: D-glucose, (2R,3S)-2,3-dimethylmalate, (R)-2-hydroxyglutarate, O-phosphoethanolamine, malathion, D-threo-isocitrate, malic acid, and 4-acetamidobutanoic acid. Cigarette smoking significant up-regulated sphingolipid metabolites, such as D-sphingosine, ceramide, N-(octadecanoyl)-sphing-4-enine, N-(9Z-octadecenoyl)-sphing-4-enine, and N-[(13Z)-docosenoyl]sphingosine, verses e-cig vaping. Overall, e-cig vaping dysregulated TCA cycle realted metabolites while cigarette smoking altered sphingolipid metabolites. Both e-cig and cigarette smoke increased nicotinic metabolites. Therefore, specific metabolic signature altered by e-cig vaping and cigarette smoking could serve as potential systemic biomarkers for early cardiopulmonary diseases.
An Experimental Study on the Performance of Corrugated Cardboard as a Sustainable Sound-Absorbing and Insulating Material
Authors: Kang Chun-Won , Kim Mina. K , Jang Eun-Suk
Published: April 2021

The continuing development of industrialization and increasing population density has led to the emergence of noise as an increasingly common problem, requiring various types of sound absorption and insulation methods to address it. Meanwhile, the recycling of resources to ensure a sustainable future for the planet and mankind is also required. Therefore, this study investigates the potential of corrugated cardboard as a resource for noise reduction. The sound absorption and insulation performance of non-perforated corrugated cardboard (NPCC) were measured, and modified corrugated boards were fabricated by drilling holes either through the surface of the corrugated board alone or through the corrugated board in its entirety. The sound absorption/insulation performance both of perforated corrugated cardboard (PCC), and perforated corrugated cardboard with multi frequency resonators (PCCM) were measured using the transfer function method and the transmission matrix method. To determine the effectiveness of NPCC, PCC, and PCCM in noise reduction, the sound pressure level was analyzed by applying it to a home blender. The results showed PCCM’s sound absorption and insulation performance to be excellent. On the basis of these findings, we propose the use of PMMC as an eco-friendly noise reduction material.
Application of Long Short Term Memory Networks for Long- and Short-term Bus Travel Time Prediction
Authors: Osman Osama , Rakha Hesham , Mittal Archak
Published: April 2021

This study introduces a comparative analysis of two deep learning (multilayer perceptron neural networks (MLP-NN) and the long short term memory networks (LSTMN)) models for transit travel time prediction. The two models were trained and tested using one-year worth of data for a bus route in Blacksburg, Virginia. In this study, the travel time was predicted between each two successive stations to all the model to be extended to include bus dwell times. Additionally, two additional models were developed for each category (MLP of LSTM): one for only segments including controlled intersections (controlled segments) and another for segments with no control devices along them (uncontrolled segments). The results show that the LSTM models outperform the MLP models with a RMSE of 17.69 sec compared to 18.81 sec. When splitting the data into controlled and uncontrolled segments, the RMSE values reduced to 17.33 sec for the controlled segments and 4.28 sec for the uncontrolled segments when applying the LSTM model. Whereas, the RMSE values were 19.39 sec for the controlled segments and 4.67 sec for the uncontrolled segments when applying the MLP model. These results demonstrate that the uncertainty in traffic conditions introduced by traffic control devices has a significant impact on travel time predictions. Nonetheless, the results demonstrate that the LSTMN is a promising tool that can has the ability to account for the temporal correlation within the data. The developed models are also promising tools for reasonable travel time predictions in transit applications.
The Movement Of Funds on the Residents' Accounts in Russia
Authors: Borodachev S. M.
Published: April 2021

The work proposes a model of funds formation in current and fixed-term (ruble and currency) accounts and transfers of funds between them. The sources of money are loans issued by commercial banks, placement of government domestic debt, the positive balance of foreign trade. The financial parameters and characteristics of the system are estimated using the Kalman filter. The adequacy of the model is confirmed by simulation modeling. It was found that the rate of creation of rubles in current accounts increased from ≈ 8% per annum in 2015-16 ≈ to 12% in 2017-18 and to 29% in 2019-20. The leakage of foreign currency from accounts (in addition to the official outflow of capital) was ≈ 12, 50, 35 billion dollars per annum during the same periods.
One-dimensional (1D) Nanostructured Materials for Energy Applications
Authors: Machín Abniel , Fontánez Kenneth , Arango Juan C , Ortiz Dayna M , De León Jimmy , Pinillas Sergio , Nicolosi Valeria , Petrescu Florian I , Morant Carmen , Márquez Francisco
Published: April 2021

At present, the world is at the peak of production of traditional fossil fuels. Much of the resources that humanity has been consuming (oil, coal and natural gas) are coming to an end. The human being faces a future that must necessarily go through a paradigm shift, which includes a progressive movement towards increasingly less polluting and energetically viable resources. In this sense, nanotechnology has a transcendental role in this change. For decades, new materials capable of being used in energy processes have been synthesized that undoubtedly will be the cornerstone of the future development of the planet.
In this review, we report on the current progress in the synthesis and use of one-dimensional (1D) nanostructured materials (specifically nanowires, nanofibers, nanotubes and nanorods), with compositions based on oxides, nitrides, or metals, for applications related to energy. Due to its extraordinary surface-volume relationship, tunable thermal and transport properties, and its high surface area, these 1D nanostructures have become fundamental elements for the development of energy processes. The most relevant 1D nanomaterials, their different synthesis procedures, and useful methods for assembling 1D nanostructures in functional devices will be presented. Applications in relevant topics such as optoelectronic and photochemical devices, hydrogen production or energy storage, among others, will be discussed. The present review concludes with a forecast on the directions towards which future research could be directed on this class of nanostructured materials.
Dimensions of Creativity in Secondary School High-Ability Students
Authors: Redó Núria Arís , Gutiérrez Mª Ángeles Millán , Cano José-Diego Vargas
Published: April 2021

Abstract: Abstract: The objective of this article is to analyze the dimensions of creativity concerning students with high abilities. Firstly a review of the most relevant scientific contributions on creativity is carried out. Next the dimensions of creativity in secondary school students who have been previously identified as high- ability students are analyzed. Those abilities associated to di-vergent thinking were assessed by means of the Torrance Test of Creative Thinking [19]. The flu-ency, flexibility and originality dimensions were assessed with the Scientific-Creative Thinking Test (TPCC, [7]). The results obtained evidence that high-ability students achieve greater scores in both the figurative creativity and scientific-creativity dimensions. A significant relationship between creativity and high ability can therefore be established. This study is of an exploratory nature and the results obtained contribute to develop future studies in application of its findings in the teaching-learning process..
P^N bridged Cu(I) Dimers Featuring both TADF and Phosphorescence. From Overview Towards Detailed Case Study of the Excited Singlet and Triplet States.
Authors: Hofbeck Thomas , Niehaus Thomas A. , Fleck Michel , Monkowius Uwe , Yersin Hartmut
Published: April 2021

We present an overview over eight brightly luminescent Cu(I) dimers of the type Cu2X2(PN)3 with X = Cl, Br, I and P^N = 2-diphenylphosphino-pyridine (Ph2Ppy), 2-diphenylphosphino-pyrimidine (Ph2Ppym), 1-diphenylphosphino-isoquinoline (Ph2Piqn) including three new crystal structures (Cu2Br2(Ph2Ppy)3, 1-Br, Cu2I2(Ph2Ppym)3, 2-I, and Cu2I2(Ph2Piqn)3, 3-I). However, we mainly focus on their photo-luminescence properties. All compounds exhibit combined thermally activated delayed fluorescence (TADF) and phosphorescence at ambient temperature. Emission color, decay time, and quantum yield varies over large ranges. For deeper characterization, we select Cu2I2(Ph2Ppy)3, 1-I, showing a quantum yield of 81 %. DFT and SOC-TDDFT calculations provide insight into the electronic structures of the singlet S1 and triplet T1 states. Both stem from metal+iodide-to-ligand charge transfer transitions. Evaluation of the emission decay dynamics, measured from 1.2 ≤ T ≤ 300 K, gives ∆E(S1-T1) = 380 cm-1 (47 meV), a transition rate of k(S1→S0) = 2.25×106 s-1 (445 ns), T1 zero-field splittings, transition rates from the triplet substates, and spin-lattice relaxation times. We also discuss the interplay of S1-TADF and T1-phosphorescence. The combined emission paths shorten the overall decay time. For OLED applications, utilization of both singlet and triplet harvesting can be highly favorable for improvement of the device performance.
Generalized Hyperharmonic Number Sums With Reciprocal Binomial Coefficients
Authors: Li Rusen
Published: April 2021

In this paper, we mainly show that generalized hyperharmonic number sums with reciprocal binomial coefficients can be expressed in terms of classical (alternating) Euler sums, zeta values and generalized (alternating) harmonic numbers.
Multi-institutional Retrospective Analysis of Carbon-ion Radiotherapy for Patients with Locally Advanced Adenocarcinoma of the Uterine Cervix
Authors: Okonogi Noriyuki , Ando Ken , Murata Kazutoshi , Wakatsuki Masaru , Noda Shin-ei , Irie Daisuke , Tsuji Hiroshi , Shozu Makio , Ohno Tatsuya
Published: April 2021

The clinical significance of carbon-ion radiotherapy (CIRT) for adenocarcinoma (AC) of the uterine cervix has been assessed in several single-institutional studies. To validate the significance, we conducted a multi-institutional survey of CIRT for locally advanced AC (LAAC) of the uterine cervix. We retrospectively analyzed the clinical outcomes of patients with stage IIB–IVA LAAC of the uterine cervix who underwent chemo-CIRT or CIRT alone between April 2010 and April 2016. Patients received 74.4 Gy (relative biological effectiveness [RBE]) in 20 fractions of CIRT or 55.2 Gy (RBE) in 16 fractions of CIRT plus 3 sessions of brachytherapy. Patients aged ≤70 years with adequate bone marrow and organ function were administered cisplatin weekly (40 mg/m2 per week for up to 5 weeks). Fifty-five patients were enrolled in this study. The median follow-up period was 67.5 months. The 5-year overall survival (OS) and local control (LC) rates were 68.6% and 65.2%, respectively. Multivariate analysis showed that the initial tumor response within 6 months was significantly associated with LC and OS. The present study represents promising outcomes of CIRT or chemo-CIRT for LAAC of the uterine cervix, especially in the cases showing initial rapid regression of the tumor.
Measurement Problem in Quantum Mechanics\\ and the Surjection Hypothesis
Authors: Bopp Fritz W.
Published: April 2021

Starting with unitary quantum dynamics, we investigate how to add quantum measurements. Quantum measurements have four essential components: the furcation, the witness production, an alignment projection, and the actual choice decision. The first two components still lie in the domain of unitary quantum dynamics. The decoherence concept explains the third contribution. It can be based on the requirement that witnesses reaching the end of time on the wave function side and the conjugate one have to be identical. In this way, it also stays within the quantum dynamics domain. The surjection hypothesis explains the actual choice
decision. It is based on a two boundary interpretation applied to the complete quantum universe. It offers a simple way to reduce these seemingly random projections to purely deterministic unitary quantum dynamics, eliminating the measurement problem.
TPR (TOTAL PHYSICAL RESPONSE) METHOD ON TEACHING ENGLISH TO EARLY CHILDHOOD
Authors: Hafidah Ruli , Dewi Nurul Kusuma
Published: April 2021

This training is carried out to provide knowledge and skills to PAUD teachers in implementing English language learning for early childhood. The subjects of the training were 30 Kindergarten (Kindergarten) and PAUD teachers of Bendosari kindergarten. The training is carried out in 3 stages, namely: (1) strengthening of materials related to the TPR (Total Physical Response) method in early childhood learning; (2) implementation of the TPR (Total Physical Response) method in learning aged children; and (3) evaluation of the material for the TPR (Total Physical Response) method in learning children. Training on the application of the TPR (Total Physical Response) method in learning English for early childhood can improve the understanding, abilities and skills of Kindergarten and PAUD teachers in the District, Sukoharjo Regency in compiling, developing, and implementing English learning using the TPR (Total Physical Response) method. Where the deepening of the material for each training stage reaches 90%. This is evidenced by the results of practice and the implications of each material. Kindergarten and PAUD teachers in Bendosari Subdistrict, Sukoharjo Regency can develop themes and materials, create and use media, choose English vocabulary according to themes and materials, and apply English learning using the TPR (Total Physical Response) method.
PRE-READING SKILL THROUGH BULLETIN BOARD MEDIA FOR CHILDREN AGE 5-6 YEARS
Authors: Ratnasari Elva Dwi
Published: April 2021

This study aimed to improve the ability of pre-reading by using bulletin boards for children aged 5-6 years. This research was a Classroom Action Research (CAR) which consists of two cycles. Each cycle consists of two meetings and four stages are carried out, namely planning, implementing the action, observing and reflecting. The subjects of this study were children aged 5-6 years at TK Khadijah III Pucung for the 2018/2019 academic year with 14 children. Data collection techniques using observation data, interviews, tests and documentation. The validity test of the data through triangulation of sources and triangulation of techniques. The data analysis technique used is qualitative analysis and quantitative analysis. The results of this classroom action research indicate an increase the pre-reading ability of each cycle. The pre-action completeness percentage obtained a result of 35% with 5 children who got a complete score. In the first cycle it increased by a percentage of 57% or 8 children who got a complete score, and in the second cycle it increased by a percentage of 86% or 12 children who got it. Based on the description above, the results of classroom action research carried out in two cycles can be concluded that bulletin board media can improve the pre-reading ability of group B at TK Khadijah III Pucung Academic Year 2018/2019.
Inundation Analysis of the Dike Breach of the Chikuma River Taking Drainage Process and House Damage into Consideration
Authors: Takeda Makoto , Sato Daisuke , Kawaike Kenji , Toyota Masashi ,   Department of Civil Engineering, Chubu University 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan,   Department of Constructional Engineering, Graduate School of Engineering, Chubu University, Aichi, Japan,   Disaster Prevention Research Institute (DPRI), Kyoto University, Kyoto, Japan,   Department of Water Environment and Civil Engineering, Faculty of Engimeering, Shinshu University, Nagano, Japan
Published: April 2021

Heavy rain and river flooding due to Typhoon No. 19 in October 2019 led to overflow and a dike breach on the left bank of the Chikuma River that caused large-scale inundation damage in Nagano City, Japan. To devise countermeasures, an inundation analysis model is an important tool. In this study, an inundation analysis model was developed to examine the inundation water behavior. The calculated inundation water depth and inundation area showed good agreement with the observed inundation water depth and the inundated area, confirming the validity of the analysis model. In addition, temporal changes of the inundation state were calculated considering the drainage process. However, the sewerage system, waterway, and drainage pump car were not taken into consideration in this analysis, and future issues for model improvement were also revealed. In addition, an analysis model with a 2 m grid was developed in the dike breach site, and the inundation water flow on roads and the fluid force around houses were obtained after taking into consideration the effect of houses. In paticular, the calculated value of the specific force exerted on damaged houses was very high. Moreover, it was proposed that house hazard should be evaluated while taking into consideration the loss of houses around the dike.
Development and Evaluation of ICT Operation Support System for Urban Flood Control Facilities
Authors: Sakae Yusuke ,   NJS Co., Ltd. 1-1-1 Shibaura, Minato-ku, Tokyo 105-0023, Japan, Endo Masaya , Nakayama Yoshikazu
Published: April 2021

This study was conducted to develop and evaluate the prediction accuracy and effectiveness of “ICT operation support system for urban flood control facilities,” which is installed in Eba catchment area in Hiroshima city, Japan. This system consists of real-time facilities monitoring technology, rainfall data from eXtended RAdar Information Network (XRAIN), and Real-time flood prediction technology. High prediction accuracy is crucial for effective control facility management using ICT operation support system. In this study, ICT operation support system was installed for effective operation of stormwater pump. The prediction accuracy and effectiveness of this system were evaluated based on the past rainfall record from XRAIN. The system takes only three minutes to distribute the urban flood prediction information, and it has been operated stably during the operation. Flood risk reduction effect can be better expected in case of central concentrated rainfall pattern.
A historical perspective on development of systems engineering discipline : a review and analysis
Authors: Hossain Niamat Ullah Ibne , Jaradat Raed , Hamilton Michael , Keating Charles , Goerger Simon
Published: April 2021

Since its inception, Systems Engineering (SE) has developed as a distinctive discipline, and there has been significant progress in this field in the past two decades. Compared to other engineering disciplines, SE is not affirmed by a set of underlying fundamental propositions, instead it has emerged as a set of best practices to deal with intricacies stemming from the stochastic nature of engineering complex systems and addressing their problems. Since the existing methodologies and paradigms (dominant pat- terns of thought and concepts) of SE are very diverse and somewhat fragmented. This appears to create some confusion regarding the design, deployment, operation, and application of SE. The purpose of this paper is 1) to delineate the development of SE from 1926-2017 based on insights derived from a histogram analysis, 2) to discuss the different paradigms and school of thoughts related to SE, 3) to derive a set of fundamental attributes of SE using advanced coding techniques and analysis, and 4) to present a newly developed instrument that could assess the performance of systems engineers. More than Two hundred and fifty different sources have been reviewed in this research in order to demonstrate the development trajectory of the SE discipline based on the frequency of publication.
Measuring Productivity and Efficiency of Traditional Chinese Medicine Hospitals from 2009 to 2016: A Bootstrap-Data Envelopment Analysis
Authors: Liu Xinliang , Chen Rui , Wu Shaopeng , Wang Jian , Li Jianan , Wang Quan , Li Hao
Published: April 2021

Objective: It was to estimate the productivity and efficiency of Traditional Chinese Medicine (TCM) hospitals to provide empirical evidence for hospital managers and policy-makers to improve the management and quality of TCM service.Methods: The data of the individual tertiary public TCM hospitals were collected from official Yearbooks of Traditional Chinese Medicine of China (2010-2017). Bootstrap-Malmquist-DEA was employed to measure the productivity and efficiency (2009-2016). SPSS23.0 was used to conduct the descriptive analysis of the input and output indicators. R3.2.1 was applied to calculate the productivity and efficiency with FEAR package. The statistical significance was set at P < 0.05.Results: The annual average growth rates of each indicator were 6.61% (health professionals), 8.15% (actual open beds), 7.08% (outpatients and inpatients) and 12.50% (discharged patients) respectively from 2009 to 2016. Except the total factor productivity change (TFPC) between 2014 and 2015, more than half of the TCM hospitals had TFPC scores over 1.000. The overall annual geo-mean TFPC score was 1.0379.Conclusions: The overall annual rate of the TFPC of the tertiary public TCM hospitals was slightly increased. The technological progress was the main driver to improve the total factor productivity. The decreased technical efficiency was more affected by the decreased scale efficiency. The TCM hospitals need to pay attention to the development and innovation of the TCM technology, thereby improving the competitiveness. The TCM hospitals managers should pursuit the high quality, high efficiency and low cost of the TCM services.
MiR-3168, miR-6125, and miR-4718 as potential predictors of cisplatin-induced nephrotoxicity in patients with head and neck cancer
Authors: Quintanilha Julia C.F. , Cursino Maria A. , Borges Jessica B. , Torso Nadine G. , Bastos Larissa B. , Oliveira Juliana M. , Cobaxo Thiago S. , Pincinato Eder , Hirata Mario H. , Geraldo Murilo V. , Lima Carmen S.P. , Moriel Patricia
Published: April 2021

Background: No biomarker is available for identifying cancer patients at risk of developing nephrotoxicity when treated with cisplatin. Methods: We performed microRNA (miRNA) sequencing using plasma collected five days after cisplatin treatment (D5) from twelve patients with head and neck cancer with and without nephrotoxicity (grade ≥2 increased serum creatinine). The most differentially expressed miRNAs between the two groups were selected for quantification at baseline and D5 in a larger cohort of patients. The association between miRNAs and nephrotoxicity was evaluated by calculating the odds ratio (OR) from univariate logistic regression. Receiver operating characteristic curves (ROC) were used to estimate the area under the curve (AUC), sensitivity, and specificity. Results: MiR-3168 (p=1.98×10−8), miR-4718 (p=4.24×10−5), and miR-6125 (p=6.60×10−5) were the most differentially expressed miRNAs and were further quantified in 43, 48, and 53 patients, respectively. The baseline expression of miR-3168 (p=0.0456, OR=1.03, 95% CI: 1.00–1.06) and miR-4718 (p=0.0388, OR=1.56, 95% CI: 1.03–2.46) were associated with an increased risk of nephrotoxicity, whereas miR-6125 showed a trend (p=0.0618, OR=1.73, 95% CI: 0.98–3.29). MiR-4718 showed the highest AUC (0.77, 95% CI: 1.74–5.8) with sensitivity of 66.76 and specificity of 79.49. Conclusions: We have provided evidence of baseline plasmatic expression of miR-3168, miR-6125, and miR-4718 as potential predictors of cisplatin-induced nephrotoxicity.
GABA Boosts Relief from Coercive Power: an fMRI study
Authors: Cheng Yawei , Martínez Róger , Chen Yu-Chun , Fan Yang-Teng , Chen Chenyi
Published: April 2021

Individuals under coercive control frequently suffer from anxiety, with recent research asserting this situation as a catalyst for certain types of violence directed towards those suffering under the most serious and insidious forms of coercive power –such as domestic violence victims. Studies researching this matter have skewed towards dissembling manipulation, or participants' obedience levels, neglecting the fact that agents under coercive power are also victims of coercive violence. In this functional magnetic resonance imaging (fMRI) study, we investigate the effects of the anxiolytic GABAA (gamma-Aminobutyric acid) modulator, lorazepam, on behavioral and neural levels in response to coercive power. We used a virtual obedience to authority paradigm inspired in Milgram's renowned experiments of the same nature. An experimenter ordered a volunteer to press a handheld button to initiate actions that carry different moral consequences, including harming or helping others. Our results showed that lorazepam administration, relative to placebo, slowed down reaction times when initiating harming behaviors, but accelerated reaction times for helping actions, despite comparable subjective ratings regarding perceived coercion. Coercive harming significantly increased activation in the amygdala, hippocampus, orbitofrontal cortex, and dorsolateral prefrontal cortex (dlPFC). After lorazepam administration, activity in the amygdala and hippocampus decreased, but activity in the dlPFC and right temporoparietal junction increased. The lower activity in the hippocampus predicted higher subjective ratings for perceived coercion. Furthermore, lorazepam administration significantly decreased the functional connectivity of the hippocampus with the dlPFC during coercive harming. Our results shed light on the coping strategies against coercion beyond merely examining its effects.