bluuebunny/crossref_metadata_2025 huggingface dataset:
Introduction pages, NBHA-CN 51(3), 2023
Authors: SESTRAS Radu E.
Published: September 2023

The papers published in Notulae Botanicae Horti Agrobotanici Cluj-Napoca, Issue 3, Volume 51, 2023 represent new exciting research in different topics of life science, respectively in plant science, horticulture, agronomy, crop science, and forestry. Among the interesting articles we invite you to find news about: Comparison of the potential of extracts from the flower, fruit pulp, and seed of Cassia fistula L. on MCF-7 breast cancer cell growth and cell migration; Evaluation of anticancer activity of Plumbago indica root extract on cervical HeLa cancer cells; Metabolome and transcriptome analyses reveal the colouring mechanism of red honeysuckle (Lonicera japonica Thunb.); Ethylene modulates root growth and mineral nutrients levels in trifoliate orange through the auxin-signaling pathway; Green nanotechnology for plant bacterial diseases management in cereal crops: a review on metal-based nanoparticles; Physiological responses of coffee (Coffea arabica L.) plants to biochar application under water deficit conditions; Gene mining and functional analysis related to maize (Zea mays L.) seed size; Phytochemical properties, antioxidant potential and fatty acids profiling of three dragon fruit species grown under sub-tropical climate; Chemical composition and anti-inflammatory effect of Phellodendron amurense Rupr. stem bark extract; Ecotype effects on photosynthesis performance using A/PFFD among Pinus nigra Arn.; Assessment of herbaceous vegetation classification using orthophotos produced from the image acquired with unmanned aerial systems.
Psychiatric and Behavioural Disorders in Children with Epilepsy (ILAE Task Force Report): Behavioural effects of epilepsy surgery
Authors: Besag Frank , Caplan Rochelle , Aldenkamp Albert , Dunn David W. , Gobbi Giuseppe , Sillanpää Matti
Published: September 2023

There are relatively few studies of the behavioural outcome of epilepsy surgery in children that have used standardised behavioural measures before and after the procedure. Those investigations that have used such measures are often on mixed groups with mixed pathology, implying that the numbers, when stratified, are very small. They are also often retrospective. Furthermore, because placebo surgery is generally not an option, the studies have been open and they are usually uncontrolled. The few available data suggest that, although individual children may benefit or deteriorate, there is little overall group effect of temporal or extratemporal surgery on behavioural/psychiatric outcome. Hemispherectomy has traditionally been associated with the expectation of marked behavioural improvement but firm data are lacking. Multiple subpial transection performed for electrical status epilepticus of slow‐wave sleep in the Landau‐Kleffner syndrome can result in marked improvements in cognition and behaviour. Vagus nerve stimulation appears to improve quality of life and mood/behaviour but again the quality of the data has been questioned. There is a need for large, prospective, multicentre, collaborative studies using standardised cognitive and behavioural measures before and after surgery to provide an adequate database on the outcome of various categories of procedures, pathologies and patients.
Metacognitive Skills of Undergraduate University Students: Study Based on Three Colombian Institutions
Authors: Gamboa Mora María Cristina , López-Rodríguez Nelly M , Vesga-Bravo Grace J. , Hernández-López Fernando
Published: September 2023

Objetivo: El objetivo de este estudio fue determinar y comparar las habilidades metacognitivas en estudiantes de pregrado en Colombia.
Método: Participaron 1204 estudiantes de tres universidades, una de carácter público y modalidad distancia; y las otras dos privadas y modalidad presencial. Se utilizó el Metacognitive Awareness Inventory (MAI) validado por Autores (2014). Para establecer diferencias significativas entre las instituciones se utilizó la Prueba HSD de Tukey, para determinar diferencias por género la prueba T y por semestre, la correlación de Pearson.
Resultados: Los estudiantes tienen un nivel alto de desarrollo de sus habilidades metacognitivas, con diferencias significativas a favor de los de modalidad distancia. No hay diferencias significativas por género, aunque las mujeres tienen promedios más altos; ni por semestre.
Conclusiones: Aunque los estudiantes tienen un buen desarrollo de sus habilidades se requiere fortalecer especialmente procesos de evaluación. Los estudiantes que se forman en metodología a distancia virtual mostraron un mayor grado de desarrollo de las habilidades metacognitivas que los de modalidad presencial, lo que podría explicarse por un mayor desarrollo de la autonomía como indicador de madurez para el aprendizaje
Gaussian Process Regression´s Hyperparameters Optimization to Predict Financial Distress
Authors: Horak Jakub , Sabek Amine
Published: September 2023

Predicting financial distress has become one of the most important topics of the hour that has swept the accounting and financial field due to its significant correlation with the development of science and technology. The main objective of this paper is to predict financial distress based on the Gaussian Process Regression (GPR) and then compare the results of this model with the results of other deep learning models (SVM, LR, LD, DT, KNN). The analysis is based on a dataset of 352 companies extracted from the Kaggle database. As for predictors, 83 financial ratios were used. The study concluded that the use of GPR achieves very relevant results. Furthermore, it outperformed the rest of the deep learning models and achieved first place equally with the SVM model with a classification accuracy of 81%. The results contribute to the maintenance of the integrated system and the prosperity of the country’s economy, the prediction of the financial distress of companies and thus the potential prevention of disruption of the given system.
Tendencias investigativas en educación formal frente al agua: revisión sistemática en la literatura científica colombiana
Authors: Castro Velásquez Freddy Enrique , Benarroch Benarroch Alicia
Published: September 2023

Este artículo de revisión sistemática analiza una muestra de 51 artículos que abordan procesos de enseñanza y aprendizaje del agua en los niveles educativos colombianos de primaria, secundaria y media, durante el periodo 2000-2020. Se pretende identificar las tendencias investigativas que giran en torno a los procesos educativos relacionados con el agua, desarrollando un mapeo bibliográfico que recurre a una escala de análisis que asigna una cifra a cada contenido dependiendo de su importancia relativa en cada investigación. Los hallazgos muestran que el nivel educativo más investigado es el secundario, seguido del medio y del primario; los contenidos curriculares más investigados son los que estudian la interacción entre el agua con el entorno vivo-social, seguido por el entorno medioambiental y el fisicoquímico; las asignaturas vinculadas con las didácticas del agua continúan siendo las ciencias naturales y sociales, y, en menor medida, tecnología, artes, matemáticas y educación física; las estrategias y recursos didácticos empleados se centran en que el educando desempeñe un rol activo y crítico en su aprendizaje, buscando superar la enseñanza transmisiva tradicional.
Modelización en la enseñanza de la anatomía macroscópica humana
Authors: Osorio-Toro Sonia , Blanco Ángel , Zambrano Alfonso
Published: September 2023

En este artículo de investigación, presenta una propuesta de modelización en la enseñanza-aprendizaje y evaluación de la anatomía macroscópica humana (AMH), realizada a partir del análisis de diversos modelos elaborados por estudiantes de segundo semestre del programa académico de Medicina y Cirugía. Estos fueron realizados en el marco de un curso corto llamado Preanatomía, en el que se realizó una observación participante, seguido por un diario de campo que registró la investigadora principal. Los modelos fueron evaluados con una rúbrica con cinco niveles de desempeño: preformal, receptivo, resolutivo, autónomo y estratégico. Se encontró que el 33.3% de los modelos de los estudiantes se encontraban en un nivel estratégico, el 25% en un nivel receptivo, el 16.6% en un nivel resolutivo, el 16.6% en un nivel preformal y el 8.3% en un nivel autónomo. En cuanto a las dificultades de los estudiantes al involucrarse en actividades de modelización, se detectaron problemas para comprender el uso de la terminología anatómica, la identificación y diferenciación de estructuras en diferentes cortes y vistas, y la ubicación espacial. Según estos resultados, la propuesta de modelización incluye las siguientes etapas: identificación de un tema de interés; la búsqueda, revisión, análisis y comparación de diferentes textos; la observación, indagación y experimentación; el desarrollo del proyecto para la construcción del modelo anatómico, trabajo interdisciplinar; socialización; mejoras al modelo anatómico y escritura de un manuscrito con el proceso de construcción del modelo.
Sanger Tree of Life HMW DNA Extraction: Manual MagAttract v1
Authors: Howard Caroline
Published: September 2023

This protocol describes the manual extraction of HMW DNA from multiple different tissue samples from a variety of species, excluding plants and fungi, intended for long-read sequencing using the Qiagen MagAttract HMW DNA extraction kit. This process is effective for a wide variety of taxonomic groups covered by the Tree of Life Programme. This protocol is particularly useful for samples with limited tissue availability, as it has consistently yielded more DNA from these smaller samples than the equivalent Automated method. The output of this protocol is HMW DNA, which depending upon yield and the genome size of the species, can be directed towards HMW DNA Pooling, HMW DNA Fragmentation: Diagenode Megaruptor® 3 for LI HiFi, HMW DNA Fragmentation: Diagenode Megaruptor® 3 for LI PacBio or HMW DNA Fragmentation: g-Tube for ULI PacBio. Acronyms HMW: high molecular weight SPRI: solid-phase reversible immobilisation HiFi: high fidelity LI: low input ULI: ultra-low input
Sanger Tree of Life HMW DNA Extraction: Manual Plant MagAttract v.2/3 v1
Authors: Todorovic Maja
Published: September 2023

This protocol describes the manual extraction of HMW DNA from plant or fungi tissue samples from a variety of species intended for long-read sequencing. It employs the Qiagen MagAttract HMW DNA extraction kit. This process is effective for approximately 60% of the plant species covered by the Tree of Life Programme, but the resulting yield of CCS data from PacBio sequencing was more stable than with the v.1 protocol. This protocol is particularly useful for samples with limited tissue availability, as it ensures the maximum amount of HMW DNA can be extracted and recovered. The output of this protocol is HMW DNA, which depending upon yield and genome size of the species, can be directed towards either HMW DNA Pooling, HMW DNA Fragmentation: Diagenode Megaruptor®3 for LI HiFi, HMW DNA Fragmentation: Diagenode Megaruptor®3 for LI PacBio or HMW DNA Fragmentation: g-Tube for ULI PacBio. This protocol was adapted from Sanger Tree of Life HMW DNA Extraction: Manual Plant MagAttract v.1 to improve sample lysis (v.2) and include a pre-shear SPRI of the HMW DNA extracted (v.3), and has since been updated to Sanger Tree of Life HMW DNA Extraction: Manual MagAttract v.4 to further improve sample lysis. Acronyms HMW: high molecular weight SPRI: solid-phase reversible immobilisation HiFi: high fidelity LI: low input ULI: ultra-low input CCS: circular consensus sequencing
Mouse transcardial perfusion v1
Authors: J Kimple Randall
Published: September 2023

Protocol for performing pump-free transcardial perfusion in mice.
Sanger Tree of Life HMW DNA Fragmentation: Covaris g-TUBE for ULI PacBio v1
Authors: oatley graeme
Published: September 2023

This protocol describes the centrifugation-mediated fragmentation of HMW DNA from samples prepared via any of the Sanger Tree of Life HMW DNA extraction protocols. The protocol produces fragments in the 8–10 kb size range using the Covaris g-Tube. The sheared DNA is suitable for downstream long read sequencing, including PacBio sequencing after ultra-low input (ULI) library preparation. This process is highly effective for DNA extracts across all taxonomic groups in the Tree of Life Programme. The output of this protocol is sheared DNA, which can be directed towards fragmented DNA clean up, using either the Manual or Automated SPRI protocols. Acronyms and abbreviations HMW: high molecular weight SPRI: solid-phase reversible immobilisation ULI: ultra-low input
Sanger Tree of Life RNA Extraction: Manual TRIzol™ v1
Authors: Juliana Vionette do Amaral Raquel
Published: September 2023

This protocol describes the manual extraction of RNA from multiple different tissue samples intended for RNA-Seq, using the TRIzol™ Reagent, based on the Thermo Fisher TRIzol™ Reagent User Guide. This process is highly effective for most taxonomic groups covered by the Tree of Life Programme. The output of this protocol is a highly concentrated RNA extract which can be diluted and submitted for both RNA-Seq and IsoSeq.
Dialogic teaching beyond words
Authors: Joanpere Foraster Mar , Egetenmeyer Regina , Soler-Gallart Marta , López de Aguileta Ane , Flecha Ramón
Published: September 2023

Scientific literature has clarified relevant contributions from dialogic teaching to the improvement of results of university students, both in face-to-face, online and hybrid sessions. There is also scientific research published about the step ahead from speech acts to communicative acts, not only in the field of teaching but also and mainly in relation to consent. There is a lack about how this step ahead is already being a base for new modalities of dialogic teaching. The study we present in this article was made through communicative methodology including a participant observation of two synchronous-hybrid master seminars of adult education and a documental analysis of all the feedbacks written at the end of each session by all students. The results show that, in those two seminars, the dialogic teaching based on communicative acts, beyond speech acts, with a dialogue that includes the scientific evidence of social impact, generates a high valuation of all students about the learning they got, the transformations they can generate with it in educational projects and, in some cases, the transformations of themselves.
Sexual disorders among temporal lobe epilepsy patients preand post-surgery
Authors: Shefer D. G. , Shershever A. S. , Boreyko V. B. , Klein A. V. , Sorokova E. V.
Published: September 2023

Objective: to investigate sexual disorders (SDs) in patients with temporal lobe epilepsy (TLE) both before and after undergoing various temporal lobe operative procedures.Material and methods. A retrospective andrological and sexologic study was conducted, utilizing catamnesis data. Multiple examination methods were employed, including semen and prostatic fluid analysis, Decourt–Dumic sperm morphotype analysis, vegetative tests, Shcherbak thermoregulation reflex examination, ultraviolet erythema test, sugar curve analysis, and electroencephalography. The study assessed the results of surgical treatment and long-term catamnesis for 120 TLE patients who had undergone various temporal lobe operative procedures (TLPs), with ages at the time of surgery ranging from 4.5 to 47 years. Among them, 82 patients (41 males and 41 females) in the main group reported complaints of SDs, representing 100% for all calculations.Results. Hypersexuality and sexual perversions were most prevalent among patients with severe mental disorders. Following TLPs, patients with mild mental disorders and cessation of epileptic seizures (EPs) experienced regression in 83.6% of SD cases. Conversely, among patients with severe mental disorders, SDs regressed in 45% of cases after TLPs. Encouraging outcomes were observed in patients with hypersexuality, which was ameliorated after the cessation of EPs, with a catamnesis period ranging from 17 to 24 years.Conclusion. This study, conducted in real-world clinical settings, supports the recommendation of surgical treatment for TLE patients with mild mental disorders. In the majority of cases, the cessation or reduction of EPs following TLPs leads to improvements in TLE manifestations, including the patient's mental state, SDs, and social adaptation.
Stimulus-induced periodic discharges in response to low-frequency photostimulation in a female patient in recovery period after middle cerebral artery stroke
Authors: Kanshina D. S. , Okuneva I. V. , Surma M. A. , Bronov O. Yu. , Nikitin S. S.
Published: September 2023

Stimulus-induced rhythmic, periodic, or ictal discharges (SIRPIDs) represent a relatively common phenomenon recorded during a long-term electroencephalogram (EEG) monitoring allowing to capture the altered state and response to auditory, tactile or nociceptive stimulation in critically ill patients. It is a nosologically non-specific phenomenon, and its relation to ictal event remains debated. We present a clinical case in which SIRPIDs were recorded in the affected dominant hemisphere in response to low-frequency photostimulation in a 60-years-old woman recovering after middle cerebral artery stroke. No ictal events were recorded during routine EEG monitoring; the patient was not in critical condition.
Psycholinguistic Aspects of Chinese Characters
Authors: Guruleva T.L. , Abdrakhmanova A.R.
Published: September 2023

The work is aimed at clarifying the psycholinguistic mechanism of Chinese hieroglyphic writing acquisition. The psycholinguistic experiment involved a survey and questionnaire among native and non-native speakers of Chinese regarding the perception of texts in two types of writing - hieroglyphic and transcriptional — according to four criteria: 1) speed of reading texts (subjective evaluation of respondents); 2) time taken to read texts in two different types of recording (objective evaluation); 3) degree of difficulty in perceiving transcribed texts (subjective evaluation of respondents); 4) number of times reading texts in pinyin transcription required to fully understand the content of the text (objective evaluation). Eight different authentic Chinese texts of different discourses with a total of 344 words were selected for the study, with the main group of respondents being native Chinese speakers of different professions, ages and gender, with different levels of English proficiency. A total of 128 respondents took part in the survey, of whom 55 respondents were native speakers of Chinese and 73 respondents were from different nationalities learning Chinese as a foreign language. The second part of the experiment was aimed at investigating the psycholinguistic mechanism of text transcoding from pinyin transcriptional recording to hieroglyphic recording by native speakers of Chinese. The results obtained allow us to say that, on average, reading texts of different discourses in pinyin transcription is 1.7 times longer than reading texts in hieroglyphic recording, reading and understanding texts written in pinyin transcription is more difficult for native speakers than reading and understanding hieroglyphic texts, especially texts of literary (poetic), folklore and ironic discourse, and when writing hieroglyphs, semantic and graphical errors are possible.
Exploring the Dynamic Relationship between Pushing Behavior and Crowd Dynamics
Authors: Uesten Ezel , Schumann Jette , Sieben Anna
Published: September 2023

Crowds, subjects of considerable complexity, have been extensively studied both as homogeneous entities and as collective sums of individual movements in various studies. However, crowd models, being grounded in physics, are limited in terms of incorporating psychological perspectives on individual behavior. Building upon the premise that crowd behavior is heterogeneous and dynamic, particularly in bottleneck scenarios, this study aims to explore the nuances of forward motion. Adopting the category system proposed by Lügering et al. (2022) (consisting the following categories: strong pushing, mild pushing, just walking, falling behind), this paper investigates the circumstances and locations where pushing or non-pushing behaviors arise, intensify, or cease within crowds approaching bottlenecks. The study utilized 14 video materials obtained from previous laboratory pedestrian experiments to examine the spatial characteristics of forward motion and pushing behavior in relation to corridor widths and varied motivational instructions. Two trained raters independently annotated these videos, achieving satisfactory inter-rater agreement (KALPHA = .65) , and a joint dataset was then created for each video. These videos consisted both high (7 videos) and low (7 videos) motivation scenarios. The importance of corridor width was also considered: four videos featured a 5.6m width, another four featured a 4.5m width, and the remaining videos displayed widths of 3.4m, 2.3m, and 1.2m twice. Our findings suggest a tendency for increased pushing behavior or an increase in the categories as individuals approach the bottleneck, regardless of the width of the corridor or the motivational instruction. Furthermore, non-pushing behaviors were predominantly observed in the areas farther away from the bottleneck. A noticeable trend was observed in high motivation scenarios, which generally exhibited more instances of pushing behavior. The effect of corridor width indicated that, in certain cases, pedestrians who push in wider corridors experience faster access to the bottleneck. However, this effect is less significant in narrower widths.
Interleukin-13: association with inflammation and cysteine proteolysis in varicose transformation of the vascular wall
Authors: Kalinin Roman E. , Konopleva Maria G. , Suchkov Igor A. , Korotkova Natalya V. , Mzhavanadze Nina D.
Published: September 2023

The present review considers current data on the structure, functions and role of interleukin-13 in the pathogenesis of vascular wall varicose transformation in terms of proteolysis and inflammatory response. It is known that interleukin-13 is able to interact with transforming growth factor-1 in diseases associated with fibrosis. The latter activates fibroblasts and excessive formation of the extracellular matrix, thereby inducing fibrosis of the vascular wall, which is one of the links in the pathogenesis of varicose veins. Also, to date, there is evidence of the interleukin-13 participation in the induction of certain proteolytic enzymes synthesis, such as matrix metalloproteinases. For the latter, participation in the transformation of the venous wall has been proven to date. The remodeling of the venous wall itself can lead to an increase in the expression of proteinases, providing a proteolytic mechanism for changing the structural organization of the venous wall in varicose veins of the lower extremities. At the same time, the involvement of lysosomal cysteine proteinases remains poorly understood. The expression and production of individual cathepsins are regulated by biologically active molecules: interleukin-1, interleukin-6, tumor necrosis factor , which are directly involved in inflammatory reactions in the wall of varicose veins. In particular, venous pathology develops in a vicious circle of inflammation with the formation of abnormal venous blood flow, chronic venous hypertension and dilation, and the recruitment of leukocytes. This leads to a further, deeper, remodeling of the walls and valves of the veins, an increase in blood pressure and the release of pro-inflammatory mediators chemokines and cytokines. In connection with the above, in order to understand the mechanisms of proteolysis in the vascular wall in varicose veins of the lower extremities, it is important to have an idea about the possible interactions of interleukin-13 with transforming growth factor-1, inflammatory cytokines, and cathepsins.
The state policy of the Russian Empire in the fight against the syphilis epidemic among foreign communities in the northeastern districts of Eastern Siberia in the 19th century
Authors: Gaidarov Gaidar M. , Alekseevskaya Tatyana I. , Demidova Tatyana V. , Sofronov Oleg Yu.
Published: September 2023

The article considers the chronology of historical events, highlighting the formation of the state policy of the Russian Empire in the fight against the spread of syphilis among foreign communities in the northeastern districts of Eastern Siberia. Archival materials are systematized, according to which the personnel, material and technical, financial support of organizational, treatment and preventive measures to combat the syphilis epidemic is assessed. The study of the materials allows to draw a reasoned conclusion that the government of the Russian Empire pursued a systematic, persistent policy of fighting to eradicate syphilis among foreign communities. In order to study and evaluate the state policy of the Russian Empire to eradicate syphilis among the foreign communities of the northeastern districts of Eastern Siberia in the 19th century, we used the historical method, which is based on the study of archival materials from the State Archives of the Irkutsk Region, indicating the organization of the fight against the epidemic syphilis among foreign communities of the northeastern districts of Eastern Siberia in the 19th century. Concern for the preservation of the population in the north-eastern districts of Eastern Siberia, newly annexed to the Russian Empire, according to the archival materials of the State Archive of the Irkutsk Region, has become an urgent task for both the government as a whole and the Governor-General of Eastern Siberia, the heads of the Yakutsk Region, Primorsky Region and Kamchatka. The state policy of the Russian Empire in the fight against the syphilis epidemic was focused on resolving issues of staffing the northern districts with medical ranks, providing them with social benefits in order to retain them for work in Eastern Siberia, identifying sources of funding and organizing the construction of syphilitic hospitals, resolving issues of ensuring the supply of medicines, pharmacy supplies, hospital supplies, clothing, food for sick people.
Análises Físico-Químicas dos Méis Industrializados e Artesanais Comercializados em Araguaína - TO
Authors: Carvalho Nagila Lessa de , Araújo Milena Dos Santos , Silva Sabrina Alexandre Ribeiro da , Damasceno Iangla Araújo de Melo
Published: September 2023

O mel apresenta muitas características atrativa, e é amplamente utilizado pela população, e por isso pode ser alvo de adulterações, por inúmeros motivos, dentre eles a tentativa de aumentar seu volume, adulterando pelo acréscimo de vários tipos de açúcares de baixo custo, como açúcar de cana, açúcar refinado de beterraba, xarope de milho, teores elevados de frutose e xarope de maltose. Tendo isso em vista, o objetivo deste trabalho foi realizar uma análise das propriedades microscópicas, organoléptica e físico-químicas sendo  os  parâmetros estudados:  reação de Fiehe, identificação de sacarose por escala Brix, acidez livre, teor de  cinzas, umidade, determinação de pH,  densidade, reação de lugol, para  investigar a presença de adulterantes na composição do mel como também alterações decorrentes do mau acondicionamento ou processamento de seis amostras de méis, sendo três delas   comercializados de forma industrial, adquiridas em supermercados e  as três restantes  foram obtidas em feiras livres e tem origem artesanal na cidade de Araguaína-TO. Como resultado, foi observado que as amostras apresentaram ao menos um parâmetro fora do padrão preconizado pelas legislações vigentes, conclui-se que os méis, possivelmente encontravam-se em condições inadequadas de armazenamento tendo em vista que na maioria das amostras apresentaram resultados em desacordo com os limites aceitáveis.
Palavras-chave:  Mel. Hidroximetilfurfural. Físico-química. Qualidade
Abstract
Honey has many resources, and is widely used by the population, and therefore can be the target of adulteration, for several reasons, among them the attempt to increase its volume, adulterating by adding various types of low-cost sugars, such as sugar Cane, Refined Beet Sugar, Corn Syrup, High Fructose and Maltose Syrup. With this in mind, the objective of this work was to carry out an analysis of the microscopic, organoleptic and physical-chemical properties, the following requirements being observed: Fiehe reaction, identification of sucrose by Brix scale, free acidity, ash content, humidity, pH efficiency, density, Lugol reaction, to investigate the presence of adulterants in the composition of honey as well as alterations resulting from poor packaging or processing of six samples of honeys, three of which are commercialized industrially, purchased in supermarkets and the remaining three were from open markets and has artisan origin in the city of Araguaína-TO. As a result, it was observed that the samples showed at least one parameter outside the standard recommended by the current legislation, it is concluded that the honeys were possibly in established processing conditions, considering that in most samples they presented results in disagreement with the accepted limits.
Keywords: Honey, Hydroxylmethylfurfural. Physicochemical. Quality.
Influence of Capillary Flow on Self-Organization of Water Droplets in Nematic Liquid Crystal
Authors: Vasileva Anastasiia A. , Pasechnik Sergey V.
Published: September 2023

The results of studying the motion of isotropic liquid drops in a homeotropic layer of liquid crystal Е7 with long-lived instabilities induced by a damped shear flow that occurs when a flat capillary is filled due to the action of capillary forces (capillary flow). An intense flow of nematics with initial homeotropic orientation leads to the appearance of orientational instabilities. In the experiments, a liquid-crystal cell with a variable gap (from 60 to 100 μm) was used. The object of the study was a 10:1 emulsion "liquid crystal – isotropic liquid". It was found that drops of isotropic liquid form various types of spatial structures. In particular, chains of drops in the region of strong deformations of LC orientation (for example, at the boundaries of the existence of long-lived regions with a changed orientation) were observed. In addition, an increased concentration of isotropic droplets occurred in the region separating the sections of the liquid crystal under the action of an electric field and in the absence of its action. Based on the analysis of microscopic images, the velocity of mutual motion of two isolated drops was determined. It made possible to estimate the interaction force between the drops (Fa = 5.6 pN) that was caused by the distortions of orientational structure in the vicinity of the drops. The results obtained are discussed within the existing theory of liquid crystals.
Analysis of subfoveal choroidal thickness alteration in relation to presence and severity of diabetic retinopathy
Authors: Tyagi Manoj , Gupta Shivani , Jain Shashi , Dwivedi Anamika , Jain Aashi
Published: September 2023

To assess alteration in subfoveal choroidal thickness in diabetics with or without diabetic retinopathy (DR) and compare it with severity of DR.

All patients attending the ophthalmic OPD fulfilling inclusion and met no exclusion criteria were enrolled in this study. All eyes underwent comprehensive and standardized ophthalmic examination. The SFCT (subfoveal choroidal thickness) was measured using high definition enhanced depth imaging spectral domain optical coherence tomography using Cirrus HD OCT Model 500.

The mean SFCT in diabetics was significantly lesser than age matched controls. It was also significantly lesser in diabetics with diabetic retinopathy as compare to diabetics without diabetic retinopathy. The SFCT was significantly decreased with increasing severity of diabetic retinopathy. The mean SFCT was also decreased in diabetic with diabetic macular edema (DME) and PRP treated DR as compared to diabetic without DME and PRP untreated DR respectively.

The SFCT could be a marker of severity of diabetic retinopathy. It was decreased in diabetics as compared to nondiabetics and was significantly decreased with increasing severity of DR and in presence of DME. PRP also significantly decreases SFCT.
Small incision cataract surgery in rural communities in Uttar Pradesh: A clinical study of postoperative complications and visual outcomes at a tertiary eye hospital
Authors: Samreen Shaeeza
Published: September 2023

To study the incidence of postoperative complications and visual outcome following manual small incision cataract surgery.

This is a hospital-based retrospective study comprised of 1020 eyes of 1020 cataract patients above 31 years without any systemic illness. This study was overseen in a rural tertiary hospital in North India from November 2020 to February 2021. All patients were analyzed according to their history, age, sex and a thorough clinical examination was done. Manual small incision cataract surgery was done for all patients, and they were examined on the first postoperative day and after 1 month.

In our study 57% of patients are male and 43% are female. The maximum number of patients were in the age group of 61–70 years. Intraoperative complications PC rent noticed in 1 case zonular dehiscence in 2 patients, and 3 patients were left aphakic. On the first post-op day, Striate keratopathy was 2%, Residual cortex 3%, FM Threads 9%, Anterior uveitis cells 3%, Blood clots & Dispersive hyphema 3%, Epithelial defects 1%, Corneal edema 4% were seen. Post-operative uncorrected vision at day one 83% of cases achieved good visual acuity (≥ 6/18) and the rest 16% were borderline acuity (<6/18-6/60), which at 1-month post-operative day good visual acuity improved to 87% of cases.

Small incision cataract surgery (SICS) with Posterior chamber intraocular lens (PCIOL) is an approved method of community-premised cataract surgery to overcome the large cataract reserve in our country it gives consistently good visual acuity post-operatively and negligible complications.
Genetics and presence of non syndromic mesiodens in siblings
Authors: Biswas Mohona , Kashyap Nilotpol , Raj Mitrasen , Patel Supreeya , Kumar Sanjeev , Kumari Ambalika
Published: September 2023

Supernumerary teeth is a well recognised phenomenon now a days. Supernumerary teeth are those that exceed normal dental formula. Mesiodens is one of the most common examples of supernumerary teeth. It can be associated with syndromes or it can be non syndromic. In this article, the role of genetics in the development of mesiodens is discussed.
On t’agathon that is the Good on the Basis Nicomachean Ethics I 1 1094a 1-3 as Interpreted by Sebastian Petrycy of Pilzno
Authors: Smolak Maciej
Published: September 2023

Arystoteles otwiera pierwszy rozdział pierwszej księgi Etyki nikomachejskiej słowami: „Każda sztuka i każde badanie, ale podobnie każde zarówno działanie jak i przedsięwzięcie, wydają się zmierzać do jakiegoś dobra. Dlatego słusznie dobro zdefiniowali jako to, do czego wszystko zmierza”. Celem artykułu jest wskazanie na trudności kryjące się w przytoczonej wypowiedzi Arystotelesa oraz przedstawienie ich rozwiązania w oparciu o jej tłumaczenie oraz komentarz autorstwa Sebastiana Petrycego z Pilzna.
Poczucie umiejscowienia kontroli i wsparcie społeczne a decyzje życiowe pełnoletnich wychowanków rodzinnej pieczy zastępczej
Authors: Wiktorowicz-Sosnowska Monika
Published: September 2023

W artykule zaprezentowano badania koncentrujące się wokół poczucia umiejscowienia kontroli i wsparcia społecznego, które mają wpływ na życiowe decyzje wychowanków rodzinnej pieczy zastępczej. Decyzje te są powiązane z brakiem autonomii lub niezależnością wychowanków w ich codziennych wyborach. Problemem dla współczesnego systemu pomocy społecznej staje się dziś usamodzielnienie, które wymaga wielowymiarowego wsparcia młodych wkraczających w samodzielne życie. To pokazuje, jak złożonym do badania zjawiskiem jest usamodzielnienie. Stopień trudności wynika z konieczności uwzględnienia wielu czynników, które w efekcie analiz mogą mieć kluczowe znaczenie dla uzyskanych konkluzji.
Rola informacji w zarządzaniu kryzysowym. Wybrane aspekty
Authors: Żebrowski Andrzej , Szkurłat Izabela
Published: September 2023

Zmieniające się środowisko funkcjonowania państwa (państw) generuje wiele złożonych zagrożeń, które utrudniają, a niekiedy i uniemożliwiają wykonywanie podstawowych zadań przez jednostki, grupy społeczne, naród i państwo. Skala i dynamika zachodzących zagrożeń, bardzo często zaskakuje rządzących i społeczeństwo. Celem niedopuszczenia do sytuacji kryzysowej uprawnione podmioty cywilne i wojskowe muszą zabezpieczać swoje potrzeby informacyjne w sposób ciągły; doceniać znaczenie informacji, potrafić je wykorzystać, by nie dopuścić do wystąpienia sytuacji kryzysowej lub zminimalizować jej następstwa. Oznacza to konieczność budowania systemu informacyjnego państwa, a także podsystemów na każdym poziomie jego funkcjonowania, które będą podstawą dla procesu decyzyjnego. Stawianie zadań, rozliczanie i umiejętne wykorzystywanie posiadanych zasobów informacyjnych w procesie zarządzania kryzysowego państwem pozwala na jego bezpieczne funkcjonowanie w otoczeniu wewnętrznym i środowisku międzynarodowym.
Artificial Intelligence, Academic Misconduct, and the Borg: Why GPT-3 Text Generation in the Higher Education Classroom is Becoming Scary
Authors: Mcllwraith Thomas , Finnis Elizabeth , Jones Sarah
Published: September 2023

We explore playfully the capacity of an artificial intelligence text generation engine called GPT-3 to produce credible academic texts. Departing from a concern raised by colleagues about the possibility of using GPT-3 to cheat in academia, particularly at the undergraduate level, we interact with the GPT-3 interface as nerdy novices to learn what it could produce. The outputs from the GPT-3 text generation engine are incredible, at times surprising, and often terrible. We point to ways in which GPT-3 might be used by students to produce written work and reasons why most instructors, most of the time, could see through what GPT-3 has produced (at least for now). In our experiments, we learn that GPT-3 can be a productive collaborator in paper design but wonder if this is ethical. In short, while fun and somewhat addictive to experiment with, we must pay attention to the potential ways that AI text generation may begin to appear in the anthropology classroom.
Estimation of Lifetime Attributable Risk (LAR) of Cancer Associated with Chest Computed Tomography Procedures in Children
Authors: Jamshidi Mohammad Hossein , Karami Aida , Ordoni Jalal , Bijari Salar
Published: September 2023

Purpose: The danger of radiation at low doses continues linearly, and without a threshold, investigations concluded that although the risk of cancer from Computed Tomography (CT) scans is low, it is not zero.
This study aims to determine the patient's radiation dose and estimate the Lifetime Attributable Risk (LAR) of cancer incidence for a single chest CT scan in children.
Materials and Methods: We divided 1,105 children into four age groups: 0 years, 5 years, 10 years, and 15 years. Dosimetric data of chest CT scan were plugged in VirtualDoseCT software, and organ dose and effective dose were calculated. The cancer risk based on organ dose is estimated according to the BEIR VII report.
Results: The highest dose in boys was related to lung (5.13 - 6.8 mSv) and heart (5.27-5.97 mSv), and in girls, lung (4.98 - 5.91 mSv), breast (4.24 - 5.21 mSv), and heart (4.9 - 5.71 mSv) had the highest dose. The highest LAR (per 100,000) was obtained for the breast in the age group of 0 years (61.01), followed by the breast for the age group of 5 years (46.16) and lung in the age group of 0 years (43.32) in girls.
Conclusion: This study shows a better concept of radiation dose in the chest CT scan in children and how much effective dose and organ dose values increase the cancer risk.
The New Anti-Estrogens with Anti-Cancer Properties for Breast Cancer
Authors: Farzanegan Zahra , Sadeghpour Fatemeh Sadat
Published: September 2023

Purpose: Considering the high prevalence of breast cancer and the radiation sensitivity of breast tissue, it is necessary to optimize the treatment process of this tumor, especially when using radiation therapy methods.
The present study was conducted to investigate the effect and complications of new anti-estrogens on the effectiveness of breast cancer treatment.
Materials and Methods: Articles were searched in PubMed, Science direct, Embassy, Cochran, and Scopus databases using the keywords Cancer AND Anti-estrogen, Breast Cancer AND anti-estrogen AND mice, Breast cancer And anti-estrogen AND rat. The authors reviewed the abstract and full text of the articles and the relevant studies were selected for systematic review.
Results: The anti-estrogens used in the reviewed studies included TAM, RAL, SS1020, SS1010, GW5638, OSP, 4-OHTAM, and TOR. Anti-estrogen-related side effects included liver and uterine complications, especially in the case of using TAM anti-estrogen (54%). Moreover, uterine hypertrophy was observed using GW5638, RAL, and SS1010 anti-estrogens; while it happened with a lower percentage than TAM, 16%, 14%, and 13%, respectively. Side effects were significantly reduced by reducing the prescribed dose. So that this reduction for TAM is from 54% to 33%. In relation to the effect of antiestrogens on tumor treatment, the most effective and least complications were related to the antiestrogen "SS1020".
Conclusion: Based on the results of reviewed studies, SS1020, which has no estrogenic and genotoxic activity, was safe and the most effective anti-estrogen against breast cancer in animals and also in humans.
Serum Chromium is Inversely Correlated with the Carotid Intima– Media Thickness in Type 2 Diabetic Subjects
Authors: Qureshi Fatima , Khoharo Haji Khan
Published: September 2023

Objective: The aim of this study was to determine and correlate the serum chromium in Carotid intima - media thickness (CIMT) in type 2 Diabetes Mellitus (T2DM) subjects.
Materials and Methods: The present case – control study included 40 healthy controls and 45 T2DM subjects that were selected through non-probability (purposive) sampling by prior inclusion and exclusion criteria. Serum chromium (Cr) was detected and measured on inductively coupled “Plasma Optical Emission Spectrophotometer” (ICP- OES)- Carotid artery was examined with a 7.5-MHz linear-array transducer (Siemens Acuson x300) sonography. Data was analyzed by Student’s t test and Chi square test in the SPSS 22.0 (USA). Linear regression model was used for predicting carotid intima media thickness. Level of confidence interval of statistical significance was 95% (P≤ 0.05).
Results: Serum Cr in controls and cases was noted 0.873 (± 0.162) and 0.281 (± 0.240) µg/ml (P= 0.001). Serum Cr proved negative correlation with random blood sugar (r= -0.145, P= 0.185), HbA1c (r= -0.145, P= 0.0001) and CIMT (r= -0.730, P= 0.0001). Multiple regression analysis model showed significant association of serum Cr (r= -0.730, P< 0.0001) and HbA1c (r= 0.754, P< 0.0001) with the CIMT.
Conclusion: The present study reported serum Cr was inversely correlated with the carotid intima - media thickness that is a marker of atherosclerosis. Cr supplements may be advised to diabetics in clinical management.
The Impact of Resistance and Aerobic Training on the Insulin Synthesis Genes Expression in Diabetic Rats
Authors: Ghofrani Mohammad Hossein , Rahimi Alireza , Alijani Eidi , Feizolahi Foad
Published: September 2023

Objective: In the last two decades, genetic studies have strongly supported the effective role of genetic factors on the synthesis of insulin from the pancreas. The purpose of this research is to determine the effect of aerobic and resistance exercises on the expression of NeruoD1 and PDX1 in pancreatic tissue, as well as serum insulin and glucose levels in type 2 diabetic rats.
Materials and Methods: 21 male wistar rats (220±10 g) were included. Then diabetic rats were randomly assigned into 3 groups: 1) control (no-training), 2) resistance training and 3) aerobic training. Exercise training lasted 10 weeks and 5 times weekly for training groups. After intervention, NeruoD1 and PDX1 expression in pancreas, insulin and glucose were compared between groups. Data compared by one way ANOVA and Tukey's post hoc test between groups (P < 0.05).
Results: Compared to control rats, resistance and aerobic training led to significant increase in serum insulin (P: 0.001, P: 0.013 respectively), PDX1 expression (P: 0.001, P: 0.001 respectively) and decrease glucose (P: 0.001, P: 0.001 respectively). Significant difference was not observed between control and aerobic groups with regard to NeruoD1 expression (P: 0.077). In addition, NeruoD1 expression in resistance group was significantly higher than aerobic and control groups (P: 0.018, P: 0.001, respectively).
Conclusion: Despite the improvement of insulin and glucose in response to both aerobic and resistance training, it seems that resistance training affects genes affecting insulin synthesis and transcription more than aerobic training
Are Electric Vehicles the Answer to a Future Clean Revolution?
Authors: Shah Rohan , Ghotankar Shambhavi , Juvekar Sanjay
Published: September 2023

The Article Abstract is not available.
The Impact of Ambient Air Pollutants on Birth Outcomes Using ARMA Model: Yazd Mother and Birth Cohort Study
Authors: Pormazar Seyedeh Mahtab , Banadaki Mohadese Dehghan , Jambarsang Sara , Ehrampoush Mohammad Hassan , Mehrparvour Amir Hoshang , Nakhostin Fahimeh , Teimouri Fahimeh
Published: September 2023

Introduction: The present study examines the association between ambient air pollution and harmful consequences at birth in Yazd, Iran during 2017-2020.
Materials and Methods: This time series study by the autoregressive (AR) and moving average (MA) or ARMA model was conducted in Yazd, Iran. Birth information including fetal sex, birth weight, birth height, and head circumference as well as preterm birth (PTB) and abortion was collected from mother and birth cohort databases. Data on air pollutants concentrations in the corresponding gestational period were obtained from fixed air monitors of Yazd Municipal Environmental Monitoring Center. The time series model statistical test was performed to find the relation between ambient air pollution and harmful consequences at birth.
Results: 2131 singleton live births were monitored for 3 years. In ARMA models, the ratio of girl births to total births (Coef: 7.943, 95% CI: 2.797, 13.089), preterm delivery (Coef: 2.915, 95% CI: 0.224, 5.606), and spontaneous abortion (Coef: 44.751, 95% CI: 26.872, 62.629) was associated with NO2 exposure. Distributed mismatch models also suggested associations between the Air Quality Index (AQI) in pregnant women with a sex-premature birth relationship (Coef: 0.001, 95% CI: 0.000, 0.001).
Conclusion: Exposure to air pollution, even at low levels, may increase the risk of sex ratio in singletons, premature birth, and spontaneous abortion. However, the results of the present study could not definitively show the relationship between air quality and other birth problems. More research studies are required to investigate the present findings.