bluuebunny/crossref_metadata_2025 huggingface dataset:
REVIEW ARTICLE PHYTOCHEMICAL AND ANTICANCER ACTIVITY OF AERIAL PARTS OF MORINGA OLEIFERA LAM
Authors:   Department of pharmacognosy,Periyar College of Pharmaceutical Sciences,Tiruchirapalli – 620021,Tamilnadu., Shantha M , Ragupathi T ,   Department of pharmacognosy Shri Indra Ganesan Institute of Medical Science College of Pharmacy, Manikandam, Tiruchirapalli– 620012, Tamilnadu., Hasan Mohamed B ,   Department of pharmacognosy Shri Indra Ganesan Institute of Medical Science College of Pharmacy, Manikandam, Tiruchirapalli– 620012, Tamilnadu., Maria Steffi P ,   Department of pharmacognosy Shri Indra Ganesan Institute of Medical Science College of Pharmacy, Manikandam, Tiruchirapalli– 620012, Tamilnadu.
Published: February 2022

The aim of the present study was to find out anticancer property of Moringa oleifera lam of the family Moringacease populary called “MIRACLE TREE”. Is a native of sub Himalayan tracts of Northern India and is widely cultivated in tropical and subtropical regions. Moringa is nature’s medicine cabinet. It is best known as excellent source of nutrition and natural energy booster. The various parts of this plant such as the leaves, roots, seed, bark, fruit, flower and immature pods act as cardiac and circulatory stimulants, Anti- cancer, Anti- inflammatory, Anti-diuretic, Antiulcer, Anti-diabetic, Antibacterial are being employed for the treatment of different oilments in the indigenous system. Moringa oleifera is a multi-purpose herbal plant used as human food and an alternative medicinal purpose wordwide. Almost all parts from Moringa can be used as source and nutrition with other useful values
IN VITRO CELL CYTOTOXICITY AND WOUND HEALING ACTIVITY OF TOPICAL FILM FORMING HYDROGEL OF PAPAIN UREA IN VERO CELLS
Authors:   Post graduate student, Department of Pharmaceutics, Periyar College of Pharmaceutical Sciences, Tiruchirapalli, Tamil Nadu, India, Sruthi Mrs. R
Published: February 2022

Wounds, whether acute or chronic, are one of the most common health problems worldwide, and medicative drugs are frequently used in wound healing. More research into wound treatment is being conducted at a rapid pace. For some wound types, enzymatic debridement of nonviable tissue remains the most effective debridement option. In theory, topical enzymes have been used in this therapy to remove necrotic tissue in the wound bed by digesting and dissolving the devitalized tissue. Papain, a plant-derived enzyme with a long history of clinical success, is one of these enzymes. The formulation of papain urea film forming gel is being used for wound repair. Vero cells were assessed in vitro for cell cytotoxicity and wound healing activity. When compared with the control, the results demonstrate significant healing activity and wound closure area. As a result of the findings of the study, the current formulation appears to be effective in healing wounds in in-vitro experiments
Do local allocation tax grants boost the issuance of road bonds? Evidence from Japan’s local governments
Authors: Miyazaki Masato
Published: February 2022

This study, by focusing on road construction projects in Japan’s local governments, conducts an empirical analysis of the relationship between the issuance of extraordinary local road improvement project bonds (subsequently abbreviated as “road bonds”) and the rate at which the redemption of the principal and interest on these bonds factors into standard financial needs (subsequently abbreviated as “inclusion rate”). Furthermore, it analyzes whether the value of local road bonds approved varies with the inclusion rate. Our analysis indicates that road bonds can be said to be linked to national treasury grants even if there exists a local allocation tax measures that allows for the redemption of the principal and interest on local bonds because local specified road maintenance and improvement projects (subsequently, “the specified projects”) combine local public subsidized projects and local public non-subsidized projects.
Science et Technologie : des acteurs du développement et de la compétition internationale.
Authors: Papon Pierre
Published: February 2022

La forte compétition internationale incite les États à renforcer leur potentiel scientifique et technique. Nous dressons un bilan des efforts dans cette perspective et traçons quelques pistes pour l’avenir. À l’aide d’indicateurs (dépenses de R&D, publications et brevets, rôle des métropoles de recherche) nous montrons que les pays investissant dans la R&D et l’innovation forment un quatuor déséquilibré. Un récent rapport de l’UNESCO, nous conduit à nous interroger sur le rôle de la recherche dans le développement durable de la planète puis nous explicitons les enjeux scientifiques et techniques de l’avenir. Nous observons que la plupart des pays sont à la recherche de stratégies pour renforcer leur potentiel scientifique et technique et participer à la compétition internationale et que dans cette perspective l’État doit jouer un rôle de « pilote ». Son action, éclairée par la prospective, doit utiliser une panoplie d’instruments avec une stratégie qui a souvent besoin d’un chef d’orchestre. Code JEL : O32
Représentation de soi et déformation du corps dans la peinture (Vinci, Caravage et Le Greco)
Authors: Freiman Bernard
Published: February 2022

L’article qu’on va lire se propose de comprendre pourquoi, après le meurtre de 1606 et l’exil qui s’ensuit, Caravage se représente dans les tableaux de cette période sous forme de victime à tête coupée. Cet « autoportrait » survient dans un contexte biblique ou évangélique comme la mort de saint Jean-Baptiste, David vainqueur de Goliath. Cette représentation n’est pas seulement une expression de culpabilité mais plonge ses rancunes dans les zones profondes de la personnalité du Caravage : obsession de la castration lien entre plaisir et douleur, désir d’agresser et de séduire le spectateur. Ces tableaux sont aussi étroitement liés aux grands événements de sa vie : meurtre de Tommasoni, exil à Naples, à Rhodes et en Sicile. Ils sont non seulement le reflet de ces grands bouleversements mais annoncent en quelque sorte ces ruptures à l’avance. En outre, ils créent avec le spectateur une relation spécifique faite de fascination et d’horreur qui structure toute la création picturale du Caravage depuis les premiers tableaux romains jusqu’aux tableaux de la fin. Chez Léonard de Vinci et chez Le Greco, ces transformations de soi sont davantage liées à des thèmes mystiques.
Société techno-capitaliste et maladie imaginative : Sami-Ali, philosophie de la vie et anthropologie contemporaine
Authors: Vallé Guillian
Published: February 2022

Dans un contexte pandémique comme le nôtre, une hypothèse serait à interroger : notre société techno-capitaliste souffrirait d’une maladie imaginative. L’analogie entre la maladie de l’individu et celle d’une société sera en effet questionnée sur ses deux plans. D’un côté, la conception thérapeutique de Sami-Ali, qui permet de penser une maladie imaginative de la personne et ses conséquences les plus graves en contexte clinique, de troubles psychosomatiques. D’un autre côté, celle de philosophes de la vie et d’anthropologues contemporains, qui pensent une maladie imaginative très similaire, tout aussi grave, mais sur le plan plus global de la civilisation moderne et de ses diverses sociétés.
Attention à la psychopathologie – de l’hyperactivité notamment !
Authors: Golse Bernard
Published: February 2022

Après avoir rappelé les fondements de l’approche psychopathologique et la place centrale qui doit être la sienne en pédopsychiatrie, l’auteur évoque les différentes composantes de la psychopathologie qui n’est pas seulement psychanalytique, avant d’aborder les apports du bébé à une meilleure compréhension des modèles de l’hyperactivité. L’article se termine sur quelques réflexions à propos des classifications dans le champ de la pathologie mentale.
Note sur le concept d’attention conjointe
Authors: Golse Bernard
Published: February 2022

L’attention conjointe est un processus important du développement, qui peut se comprendre à la fois d’un point de vue psychanalytique et d’un point de vue cognitif. Ce processus fait partie des liens qui unissent le bébé et l’adulte tout en participant à leur différenciation progressive. Les apports de D. W. Winnicott en ce domaine nous sont encore et toujours essentiels.
Intuition, intention, inspiration
Authors: Vamos Julianna
Published: February 2022

L’attention est un regard et une écoute soutenus qui peuvent être décomposés en plusieurs mouvements internes lors des soins aux bébés, avec ses parents. On peut la développer, elle cherche à être contenante. La rêverie du thérapeute est concomitante à cette attention. Son intuition et son inspiration peuvent s’exprimer dans la rencontre concrète avec la famille. L’intention du thérapeute avec toutes les facettes de l’attention accompagne le processus de devenir parents et favorise la reconnaissance des initiatives du bébé.
Empathie et attention en périnatalité : de la construction partagée des capacités attentionnelles à la capacité créative individuelle ?
Authors: Simas Roberta
Published: February 2022

Cet article propose une petite révision des mécanismes de l’empathie et de l’attention au cours du développement précoce du bébé. Nous regardons ensuite les liens entre différentes approches (neuroscientifiques, théories du développement et psychodynamiques) concernant ces processus, enfin, nous examinons le rôle des acteurs du soin psychique périnatal lorsque certains mécanismes se retrouvent entravés par la psychopathologie parentale.
Proto- thada et régulation tonico-sensorielle
Authors: Mensah Philippe
Published: February 2022

Les modes d’expressions émotionnelles du bébé sont parfois mystérieuses pour les adultes qui les entourent. Le corps et le psychisme sont indifférenciés et l’expression émotionnelle se situe au niveau primaire. Par un processus développemental dit d’intégration, les modes de régulations et d’expressions vont s’instaurer. Le regard développemental et les repères qui vont avec sont donc primordiaux. Le tonus tient une place central dans tout cela. Il suit une progression neurodéveloppementale qui vient étayer l’expression des émotions et de la vie psychique.
Philosophie du premier âge : l’émergence du sujet au miroir de l’attention
Authors: Catteeuw Laurie
Published: February 2022

Cet article trace les contours de la philosophie du premier âge. Elle a été conçue à partir d’une réflexion sur les représentations sociales du nourrisson et du jeune enfant, nourrie d’une expérience de terrain quotidienne, durant plusieurs années, en crèche. Elle se fonde sur leurs compétences et leur besoin de s’humaniser, notamment pour naître à la pensée. La philosophie du premier âge a pour outils l’observation, la dialectique entre attention suscitée et portée, l’espace potentiel. Du côté de l’enfant, il s’agit de l’accompagner dans son besoin de penser parce qu’il découvre son corps. Du côté des adultes qui en prennent soin, la philosophie du premier âge a pour but de les étayer dans leur fonction de pourvoyeurs de contenants immatériels, à partir desquels le jeune enfant va élaborer son individualité, son image corporelle et sa conscience de soi. La philosophie du premier âge est une philosophie pratique conçue pour répondre aux besoins de la petite enfance.
Le langage, les langues et la culture : des objets d’attention conjointe en crèche
Authors: Salvi Véronique , Prince Agbodjan Bertha
Published: February 2022

Le langage, les langues et la culture sont des objets incontournables d’attention conjointe en structure d’accueil petite enfance. Le projet « Langage, langues et culture » de la direction des familles et de la petite enfance de la Ville de Paris en né en 2018, et répond à un double objectif : valoriser l’ensemble des pratiques existantes et travailler davantage encore la place du langage et des langues dans les structures d’accueil du jeune enfant à Paris, afin de favoriser les compétences langagières des enfants et l’épanouissement de chacun. Un autre enjeu du projet est de faire se rencontrer, travailler et élaborer ensemble deux mondes qui se côtoient peu : celui de la recherche universitaire et celui des professionnel(le)s de la petite enfance (en structure d’accueil, pmi , centre de loisirs). La réussite de ce projet est ainsi fondée sur une approche globale et inclusive de tous les acteurs : professionnels, universitaires et partenaires. L’organisation des échanges s’est effectuée autour de trois axes de travail pour répondre aux objectifs du projet : le langage au quotidien, l’éveil culturel et le plurilinguisme. Différentes actions se sont mises en place : conférences, recherche-action-formation, et ont obtenu le patronage de la Commission nationale française de l’ unesco .
L’attention, une construction relationnelle ?
Authors: Morel Manela Dominique
Published: February 2022

La lecture individuelle aux bébés, pratiquée depuis de nombreuses années par l’association A.C.C.E.S., permet le développement de l’intérêt et du plaisir à construire des histoires tout en étayant leur capacité d’attention, grâce aux choix sélectifs des enfants et aux échanges attentifs avec la lectrice. Nous en donnons un exemple en appui avec le récit détaillé d’une lectrice. Le texte s’appuie sur les recherches développementales du nourrisson et les apports des linguistes qui ont montré l’importance de l’élaboration des premières angoisses, notamment les angoisses de séparation. Le jeu et le langage du récit nourrissent l’évolution de la construction et de la qualité du langage oral.
Analysis of over current relay and hybrid filter including the utilization of SFCL in a distribution network with DG
Authors: Dhara Saumen ,   Department of Electrical Engineering, IIT(ISM), Dhanbad, 826004, Jharkhand, India, Sadhu Pradip Kumar , Shrivastav Alok Kumar ,   Department of Electrical Engineering, Techno International Batanagar, Kolkata, 700141, India
Published: February 2022

Recently, as technology advances, demand for electrical energy has increased at an unprecedented rate in the power system network. With the growing importance of renewable energy assets and the global expansion of distributed generation (DG) efficiency, grid fault analysis is critical for increasing the efficiency and resilience of the power system. Apart from fault current, the interconnection of distributed generators in the distribution network results in an increase in system harmonics, as well as a halt in the operation of the overcurrent relay due to backward directed fault current. However, since the SFCL is considered to be more effective when used with distributed generators, the investigation of a protective relay due to the employment of SFCL is particularly necessary as a substitute strategy for limiting fault current in the distribution network. Additionally, many electrical customers continually require quality control, depending on the quality of the grid power it delivers and the performance of the terminal device. However, a variety of external and internal variables have an effect on the quality of energy delivered to the end consumer. Itos similar to fluctuations in tension and frequency, as well as failures. Such power quality concerns erode equipmentos long-term capability and performance. These concerns should be addressed in terms of harmonic reduction via the use of hybrid filtering in order to maximise the efficacy of consumer goods and overall device output. This study proposes a control strategy for the filter to eliminate harmonics and a rectification method for the overcurrent relay employing voltage components for the purpose of applying SFCL, as well as the notion of DG, in a power distribution framework. To validate the suggested approach, a malfunction with an overcurrent relay was simulated using a combination of DG and SFCL. The MATLAB/SIMULINK environment is used to simulate the desired control strategy and see the result.
Linear and nonlinear non-Fredholm operators and their applications
Authors: Efendiev Messoud , Vougalter Vitali
Published: February 2022

In this survey we discuss the recent results on the existence in the sense of sequences of solutions for certain elliptic problems containing the non-Fredholm operators. First of all, we deal with the solvability in the sense of sequences for some fourth order non-Fredholm operators, such that the methods of the spectral and scattering theory for Schrödinger type operators are used for the analysis. Moreover, we present the easily verifiable necessary condition of the preservation of the nonnegativity of the solutions of a system of parabolic equations in the case of the anomalous diffusion with the negative Laplacian in a fractional power in one dimension, which imposes the necessary form of such system of equations that must be studied mathematically. This class of systems of PDEs has a wide range of applications. We conclude the survey with several new results nowhere published concerning the solvability in the sense of sequences for the generalized Poisson type equation with a scalar potential.
From short exact sequences of abelian categories to short exact sequences of homotopy categories and derived categories
Authors: Wu Yilin , Zhou Guodong
Published: February 2022

We show that a short exact sequence of abelian categories gives rise to short exact sequences of abelian categories of complexes, homotopy categories and unbounded derived categories, refining a result of J. Miyachi.
A structure-preserving doubling algorithm for solving a class of quadratic matrix equation with $ M $-matrix
Authors: Chen Cairong
Published: February 2022

Consider the problem of finding the maximal nonpositive solvent $ \varPhi $ of the quadratic matrix equation (QME) $ X^2 + BX + C = 0 $ with $ B $ being a nonsingular $ M $-matrix and $ C $ an $ M $-matrix such that $ B^{-1}C\ge 0 $. Such QME arises from an overdamped vibrating system. Recently, under the condition that $ B - C - I $ is a nonsingular $ M $-matrix, Yu et al. (Appl. Math. Comput., 218 (2011): 3303–3310) proved that $ \rho(\varPhi)\le 1 $ for this QME. In this paper, under the same condition, we slightly improve their result and prove that $ \rho(\varPhi) < 1 $, which is important for the quadratic convergence of the structure-preserving doubling algorithm. Then, a new globally monotonically and quadratically convergent structure-preserving doubling algorithm for solving the QME is developed. Numerical examples are presented to demonstrate the feasibility and effectiveness of our method.
Approximate solution of nonlinear fuzzy Fredholm integral equations using bivariate Bernstein polynomials with error estimation
Authors: Karamseraji Sima ,   Department of Mathematics, Karaj Branch, Islamic Azad University, Karaj, Iran, Ziari Shokrollah , Ezzati Reza ,   Department of Mathematics, Firoozkooh Branch, Islamic Azad University, Firoozkooh, Iran
Published: February 2022

This paper is concerned with obtaining approximate solutions of fuzzy Fredholm integral equations using Picard iteration method and bivariate Bernstein polynomials. We first present the way to approximate the value of the multiple integral of any fuzzy-valued function based on the two dimensional Bernstein polynomials. Then, it is used to construct the numerical iterative method for finding the approximate solutions of two dimensional fuzzy integral equations. Also, the error analysis and numerical stability of the method are established for such fuzzy integral equations considered here in terms of supplementary Lipschitz condition. Finally, some numerical examples are considered to demonstrate the accuracy and the convergence of the method.
Completeness of metric spaces and existence of best proximity points
Authors: Khan Arshad Ali ,   Department of Mathematics, School of Science, University of Management and Technology, C-II, Johar Town, Lahore 54770, Pakistan, Ali Basit , Nazir Talat , Sen Manuel de la ,   Department of Mathematical Sciences, University of South Africa, Florida 0003, South Africa,   Institute of Research and Development of Processes, University of the Basque Country, 48940, Leioa, Bizkaia, Spain
Published: February 2022

In this paper, we discuss the existence of best proximity points of new generalized proximal contractions of metric spaces. Moreover, we obtain a completeness characterization of underlying metric space via the best proximity points. Some new best proximity point theorems have been derived as consequences of main results in (partially ordered) metric spaces.
An improved upper bound for the dynamic list coloring of 1-planar graphs
Authors: Hu Xiaoxue ,   School of Science, Zhejiang University of Science & Technology, Hangzhou 310023, China, Kong Jiangxu ,   School of Science, China Jiliang University, Hangzhou 310018, China
Published: February 2022

A graph is $ 1 $-planar if it can be drawn in the plane such that each of its edges is crossed at most once. A dynamic coloring of a graph $ G $ is a proper vertex coloring such that for each vertex of degree at least 2, its neighbors receive at least two different colors. The list dynamic chromatic number $ ch_{d}(G) $ of $ G $ is the least number $ k $ such that for any assignment of $ k $-element lists to the vertices of $ G $, there is a dynamic coloring of $ G $ where the color on each vertex is chosen from its list. In this paper, we show that if $ G $ is a 1-planar graph, then $ ch_{d}(G)\leq 10 $. This improves a result by Zhang and Li [16], which says that every 1-planar graph $ G $ has $ ch_{d}(G)\leq 11 $.
Immuno-epidemiological co-affection model of HIV infection and opioid addiction
Authors: Gupta Churni ,   Faculty of Pharmacy, University of Montreal, Montreal, QC, Canada, Tuncer Necibe , Martcheva Maia ,   Department of Mathematical Sciences, Florida Atlantic University, Boca Raton, FL, United States of America,   Department of Mathematics, University of Florida, Gainesville, FL, United States of America
Published: February 2022

In this paper, we present a multi-scale co-affection model of HIV infection and opioid addiction. The population scale epidemiological model is linked to the within-host model which describes the HIV and opioid dynamics in a co-affected individual. CD4 cells and viral load data obtained from morphine addicted SIV-infected monkeys are used to validate the within-host model. AIDS diagnoses, HIV death and opioid mortality data are used to fit the between-host model. When the rates of viral clearance and morphine uptake are fixed, the within-host model is structurally identifiable. If in addition the morphine saturation and clearance rates are also fixed the model becomes practical identifiable. Analytical results of the multi-scale model suggest that in addition to the disease-addiction-free equilibrium, there is a unique HIV-only and opioid-only equilibrium. Each of the boundary equilibria is stable if the invasion number of the other epidemic is below one. Elasticity analysis suggests that the most sensitive number is the invasion number of opioid epidemic with respect to the parameter of enhancement of HIV infection of opioid-affected individual. We conclude that the most effective control strategy is to prevent opioid addicted individuals from getting HIV, and to treat the opioid addiction directly and independently from HIV.
Inverse problem approaches for mutation laws in heterogeneous tumours with local and nonlocal dynamics
Authors: Alwuthaynani Maher ,   Division of Mathematics, University of Dundee, Dundee DD1 4HN, Scotland, UK, Eftimie Raluca , Trucu Dumitru ,   Laboratoire Mathématiques de Besançcon, UMR-CNRS 6623, Université de Bourgogne Franche-Comté, 16 Route de Gray, Besançcon 25000, France
Published: February 2022

Cancer cell mutations occur when cells undergo multiple cell divisions, and these mutations can be spontaneous or environmentally-induced. The mechanisms that promote and sustain these mutations are still not fully understood.

This study deals with the identification (or reconstruction) of the usually unknown cancer cell mutation law, which lead to the transformation of a primary tumour cell population into a secondary, more aggressive cell population. We focus on local and nonlocal mathematical models for cell dynamics and movement, and identify these mutation laws from macroscopic tumour snapshot data collected at some later stage in the tumour evolution. In a local cancer invasion model, we first reconstruct the mutation law when we assume that the mutations depend only on the surrounding cancer cells (i.e., the ECM plays no role in mutations). Second, we assume that the mutations depend on the ECM only, and we reconstruct the mutation law in this case. Third, we reconstruct the mutation when we assume that there is no prior knowledge about the mutations. Finally, for the nonlocal cancer invasion model, we reconstruct the mutation law that depends on the cancer cells and on the ECM. For these numerical reconstructions, our approximations are based on the finite difference method combined with the finite elements method. As the inverse problem is ill-posed, we use the Tikhonov regularisation technique in order to regularise the solution. Stability of the solution is examined by adding additive noise into the measurements.
Multi-attribute scientific documents retrieval and ranking model based on GBDT and LR
Authors: Tian Xuedong ,   School of Cyber Security and Computer, Hebei University, Baoding 071002, China, Wang Jiameng , Wen Yu , Ma Hongyan ,   Hebei Machine Vision Engineering Research Center, Hebei University, Baoding 071002, China,   Institute of Intelligent Image and Document Information Processing, Hebei University, Baoding 071002, China,   School of Mathematics and Information Science, Hebei University, Baoding 071002, China
Published: February 2022

Scientific documents contain a large number of mathematical expressions and texts containing mathematical semantics. Simply using mathematical expressions or text to retrieve scientific documents can hardly meet retrieval needs. The real difficulty in retrieving scientific documents is to effectively integrate mathematical expressions and related textual features. Therefore, this study proposes a multi-attribute scientific documents retrieval and ranking model based on GBDT (gradient boosting decision tree) and LR (logistic regression) by integrating the expressions and text contained in scientific documents. First, the similarities of the five attributes are calculated, including mathematical expression symbols, mathematical expression sub-forms, mathematical expression context, scientific document keywords and the frequency of mathematical expressions. Next, the GBDT model is used to discretize and reorganize the five attributes. Finally, the reorganized features are input into the LR model, and the final retrieval and ranking results of scientific documents are obtained. The experiment in this study was carried out on the NTCIR dataset. The average value of the final MAP@20 of the scientific document recall was 81.92%. The average value of the scientific document ranking nDCG@20 was 86.05%.
Identification of protein functions in mouse with a label space partition method
Authors: Li Xuan ,   College of Information Engineering, Shanghai Maritime University, Shanghai 201306, China, Lu Lin , Chen Lei ,   Department of Radiology, Columbia University Medical Center, New York 10032, USA
Published: February 2022

Protein is very important for almost all living creatures because it participates in most complicated and essential biological processes. Determining the functions of given proteins is one of the most essential problems in protein science. Such determination can be conducted through traditional experiments. However, the experimental methods are always time-consuming and of high costs. In recent years, computational methods give useful aids for identification of protein functions. This study presented a new multi-label classifier for identifying functions of mouse proteins. Due to the number of functional types, which were termed as labels in the classification procedure, a label space partition method was employed to divide labels into some partitions. On each partition, a multi-label classifier was constructed. The classifiers based on all partitions were integrated in the proposed classifier. The cross-validation results proved that the proposed classifier was of good performance. Classifiers with label partition were superior to those without label partition or with random label partition.
Analytic modelling of passive microfluidic mixers
Authors: Bonament Alexi , Prel Alexis , Sallese Jean-Michel , Lallement Christophe , Madec Morgan
Published: February 2022

This paper deals with a new analytical model for microfluidic passive mixers. Two common approaches already exist for such a purpose. On the one hand, the resolution of the advection-diffusion-reaction equation (ADRE) is the first one and the closest to physics. However, ADRE is a partial differential equation that requires finite element simulations. On the other hand, analytical models based on the analogy between microfluidics and electronics have already been established. However, they rely on the assumption of homogeneous fluids, which means that the mixer is supposed to be long enough to obtain a perfect mixture at the output. In this paper, we derive an analytical model from the ADRE under several assumptions. Then we integrate these equations within the electronic-equivalent models. The resulting models computed the relationship between pressure and flow rate in the microfluidic circuit but also takes the concentration gradients that can appear in the direction perpendicular to the channel into account. The model is compared with the finite element simulation performed with COMSOL Multiphysics in several study cases. We estimate that the global error introduced by our model compared to the finite element simulation is less than 5% in every use case. In counterparts, the cost in terms of computational resources is drastically reduced. The analytical model can be implemented in a large range of modelling and simulation languages, including SPICE and hardware description language such as Verilog-AMS. This feature is very interesting in the context of the in silico prototyping of large-scale microfluidic devices or multi-physics devices involving microfluidic circuits, e.g. lab-on-chips.
AI-driven adaptive reliable and sustainable approach for internet of things enabled healthcare system
Authors: Zahid Noman , Sodhro Ali Hassan , Kamboh Usman Rauf , Alkhayyat Ahmed , Wang Lei
Published: February 2022

Artificial Intelligence (AI) driven adaptive techniques are viable to optimize the resources in the Internet of Things (IoT) enabled wearable healthcare devices. Due to the miniature size and ability of wireless data transfer, Body Sensor Networks (BSNs) have become the center of attention in current medical media technologies. For a long-term and reliable healthcare system, high energy efficiency, transmission reliability, and longer battery lifetime of wearable sensors devices are required. There is a dire need for empowering sensor-based wearable techniques in BSNs from every aspect i.e., data collection, healthcare monitoring, and diagnosis. The consideration of protocol layers, data routing, and energy optimization strategies improves the efficiency of healthcare delivery. Hence, this work presents some key contributions. Firstly, it proposes a novel avant-garde framework to simultaneously optimize the energy efficiency, battery lifetime, and reliability for smart and connected healthcare. Secondly, in this study, an Adaptive Transmission Data Rate (ATDR) mechanism is proposed, which works on the average constant energy consumption by varying the active time of the sensor node to optimize the energy over the dynamic wireless channel. Moreover, a Self-Adaptive Routing Algorithm (SARA) is developed to adopt a dynamic source routing mechanism with an energy-efficient and shortest possible path, unlike the conventional routing methods. Lastly, real-time datasets are adopted for intensive experimental setup for revealing pervasive and cost-effective healthcare through wearable devices. It is observed and analysed that proposed algorithms outperform in terms of high energy efficiency, better reliability, and longer battery lifetime of portable devices.
(Dés)intégrer autrui dans l’ordre rationnel. Machinerie, hétéronomie et réification dans les romans de Sade et Beckett
Authors: Franck Thomas
Published: February 2022

Cet article s’attarde sur les lectures que Theodor W. Adorno réalise des œuvres romanesques de Sade et de Beckett et, plus largement, de l’histoire littéraire française du XVIIIe au XXe siècle lue au travers du prisme de la dialectique négative inhérente à sa Théorie critique. La thèse de la Dialektik der Aufklärung d’une rechute de la Raison dans le mythique et l’irrationnel postule que le culte d’une ratio instrumentale et non critique entraîne une barbarie destructrice. Ce processus est le fruit d’un retournement de l’Aufklärung en son envers négatif sous l’action d’une subsomption collective à l’ordre rationnel et à l’hétéronomie politique. Les Noten zür Literatur puis l’Ästhetische Theorie ont porté leur attention sur la tradition française afin de montrer comment certaines formes littéraires gravaient, négativement, dans leur esthétique même les différentes conjonctures de cette Aufklärung. Il est donc question d’interpréter et de prolonger, d’un point de vue rhétorique et énonciatif, les analyses philosophiques d’Adorno à propos des œuvres sadienne et beckettienne – entre lesquelles il existe un retournement dialectique – tout en évaluant l’actualité de sa Théorie critique pour une relecture de l’histoire romanesque de France.
Structure de l’intrigue : limites de la géométrie et de la symétrie dans Le Château des destins croisés d’Italo Calvino
Authors: Macura Sergej
Published: February 2022

Le caractère changeant du sens des mêmes motifs et narrathèmes selon leur position est un des traits les plus importants des récits entrelacés dans l’œuvre Le Château des destins croisés d’Italo Calvino, surtout si les mêmes cartes sont « lues » en sens inverse dans cette « machine littéraire ». L’auteur a réussi à intégrer dans les conventions assez figées de la narration fabuleuse des ornements inventifs, tels que les contradictions, les palimpsestes et les incontournables polysémies, là où un récit est construit selon les mêmes cartes par un narrateur différent. Cet article analyse le développement de la trame qui, conformément à la disposition des cartes sur la table, suit le schéma visiblement rigide de la forme géométrique du rectangle où le début de chaque récit suivant a sa place dans l’aire où se termine le récit précédent de façon que le quatrième récit ferme la figure géométrique au commencement du premier récit. Le cinquième et le sixième récits forment les bras vertical et horizontal de la croix et épuisent toute la matière imagée qui est interprétée par les autres cartes-narrateurs selon des formes et, par conséquent des interprétations, différentes. Dans le chapitre « Toutes les autres histoires » se construit un tourbillon de nouveaux sens et de nouveaux conflits entre les narrateurs de plus en plus agités si bien que le narrateur anonyme à la première personne avoue perdre le fil de son propre récit dans le tumulte général. Toute la liberté de la création des récits n’empêche pas que certains éléments soient prédéterminés et qu’ils facilitent une interprétation plus précise : tous les narrateurs sont représentés par une des cartes qui sont appelées de cour (valet, cavalier, reine ou roi) ; ce n’est que dans le récit 6 que plus de deux cartes de l’Arcane majeur apparaissent d’affilée, tandis que dans les cartes numérotées de l’Arcane mineur (de 1 à 10), ce n’est que dans les récits 3 et 4 que se suivent plus de deux cartes. En outre, tous les narrateurs des 6 premiers récits sont des hommes, alors que les quatre reines figurent dans la partie finale, dans des positions relativement symétriques. L’article essaie d’établir quand les récits suivent les fonctions du conte de Vladimir Propp, et quand ils agissent comme des parodies des contes.
The Weight of Water: Some Implications of Textual Fluidity for the Study of Comparative Literature
Authors: Purdy Elizabeth
Published: February 2022

This article looks at the role that water and fluidity can play within the field of comparative literature. Using the example of two recent novels, it explores the idea that water imagery in a narrative can act as a signal towards a wider sense of fluidity within the form of the text. The article looks specifically at three properties of water which can also be traced within literature: its perpetual motion, its shapelessness, and its connective potential. Through an exploration of these properties, this article aims to demonstrate how a fluid reading can help us to find new points of comparison which work at both an intertextual and an intratextual level.
World-Ecological Literature and the Animal Question
Authors: O’Key Dominic
Published: February 2022

In recent years, the Marxist method of world-literary theory has given birth to world-ecological literary criticism, a practice of materialist comparativism that analyses how literary texts register the environmental crises of capitalist modernity. Although its practitioners have penned incisive essays on literary engagements with the extraction and exhaustion of resources like water, oil and cacao, there has been no work published on industrialized animal agriculture and the global expansion of meat production. This is not a simple omission, but rather a product of Marxism’s longstanding ambivalence towards animals. With this argument as the foundation of this essay, I set out to both extend and challenge the world-ecological analytic by paying attention to literary registrations of meat production across different socio-ecological regimes. I do so by turning to Jean-Baptiste Del Amo’s 2016 novel, Règne animal, published in English as Animalia in 2019. I show how the novel embraces forms of literary naturalism which, by depicting farm workers and their animals as jointly expendable to the laws of profitability, registers the meatification of France across two centuries. Yet if naturalism ultimately depicts human characters who are powerless to stop predetermined natural laws, then to what extent does Animalia truly challenge the conditions of factory farming it wishes to expose? Put differently, what are the affordances and limitations of naturalist form for critically mapping factory farming?
Gümüşhane İlinin Kültürel Turizm Potansiyeli
Authors: ÖKTEM Elif
Published: February 2022

Turizm illerin ekonomik gelişimlerini sağlamada önemli katkılar sunan aktif sektörlerden birisidir. Kültür turizmi son yıllarda turistlerin en çok tercih ettiği turizm türlerinden birisi olmuştur. İllerin kültür turizmi kaynakları bakımından zengin olması, illerin turizm sektöründe yer edinmeleri açısından avantaj elde etmesini sağlamaktadır. Bu durum ilde bulunan kültür turizmi kaynaklarının önemini artırmakta ve kültürel varlıkların sosyal ve ekonomik olarak önemini ortaya koymaktadır. Gümüşhane ili taşınmaz kültür varlıkları, sit alanları, tarihi yerleşim yerleri ve müze gibi birçok kültür turizmi kaynağına sahip bir ildir. Bunca zengin ve ilgi çekici potansiyele sahip olmasına karşın henüz hak ettiği ilgiyi görememiştir. Kültürel varlıklarının turizme kazandırılması Gümüşhane ilinde turizmin geliştirilmesi açısından oldukça önemli bir konudur. Bu araştırmada, Gümüşhane ili kültür turizmi bağlamında incelenerek, kültür turizmi kaynakları değerlendirilerek (taşınmaz kültür varlıkları, sit alanları, tarihi yerleşim yerleri ve müze) turizm potansiyelinin ortaya konulması, bu potansiyelin tanıtılması, kültürel mirasın yaşatılarak toplum bilincinin sağlanması için katkılar sunmak amaçlanmıştır. Bu bağlamda bu çalışmada nitel araştırma yöntemi olan doküman analizi yönteminden yararlanılmıştır. Çeşitli kaynaklar incelenerek Gümüşhane ilinin turizm sektöründe tanıtımının yapılarak yer edinebilmesi için bazı öneriler sunulmuştur.
Design of a Mobile Application to Help Overweight People in Peru with the use of Chatbots
Authors:   Universidad María Auxiliadora & Av. Canto Bello 431, San Juan de Lurigancho, Peru, Siguas Rosa Perez , Solis Hernan Matta , Solis Eduardo Matta
Published: February 2022

In this research we have seen that in Peru there is a large number of overweight people in a range that exceeds at least 30% depending on the age range, between 20 and 29 years there is 30.40% overweight, between 30 and 39 years there is 43.70% overweight, between 40 and 49 years there is 46.80% overweight, Between 50 and 59 years old there is a 43.30% of overweight and from 60 years old onwards there is a 38.50% of overweight, that is why we have proposed a prototype of a mobile application, whose main function is to help through the interaction of chatbots technology to have better control over their feeding and physical The development of the application will be done with an agile methodology, using the Scrum framework and the Balsamiq Mockup tool that will help us to design the prototypes of each module of the application. In the case of the study the requirements were made, and the planning of each sprint to carry out the application in a determined time. As a result, the design of the application is shown with modules to register users, register their weight and height to calculate their Body Mass Index (BMI), a section to interact in a chat to make any consultation, and finally a list of recipes with healthy dishes. This application will be very useful for all people who want to improve their health since it is not only for aesthetics, but also to prevent fatal diseases at an early age. Keywords— Chatbots, Design, Mobile Application, Overweight.
The Method for Identification of Radars Measurements of Nearby Objects Tracking
Authors:   Ivan Kozhedub Kharkiv National Air Force University, Ukraine, Kharkiv, 61023, Khudov Hennadii , Ruban Igor , Pievtsov Hennadii , Makoveichuk Oleksandr , Popkov Oleh , Shabanov Danylo , Baranov Yurii , Solomonenko Yuriy , Kryvosheiev Vitalii , Khudov Rostyslav
Published: February 2022

— The paper proposes the method for identification of radars measurements of nearby objects tracking. The method for identification of radars measurements of nearby objects tracking, in contrast to the known ones, assumes the next. Solving the optimization problem of searching for a hypothesis of joint identification of objects and measurements. The solution is optimal according to Bayes' criterion. The solution of the optimization problem of joint identification of objects and measurements is reduced to the assignment problem with the subsequent choice of a hypothesis. The choice of hypothesis is presented in the form of an identification matrix. The presence of background objects in the viewing area is taken into account. The procedure for enumerating hypotheses is rather cumbersome even with a small number of objects (10-12 objects). Therefore, the subject of further research is to find ways to reduce the computational costs of solving the optimization problem. Keywords— method, identification, radar, measurement, nearby object, tracking, hypothesis
Smart Monitoring System and Early Warning Water Level ―SMOORTY‖ using Raspberry Pi Technology
Authors:   Computer Science Department, School of Computer Science, Bina Nusantara University, Jakarta Indonesia 11480, Chouwanto Edward Arlis , Wongso Rini , Yesmaya Violitta
Published: February 2022

The river has become an inseparable part of human life, but river water's excessive overflowing can lead to disaster, namely flooding. Floods are quite common globally, but the people are often not ready to deal with it as there is no early warning to the public about the upcoming flood. The development of a smart monitoring city or referred to as SMOORTY in this study was made to provide a warning of the possibility of a flood disaster. SMOORTY application can help as one solution to improve the community's alertness in dealing with floods by providing an early warning notification through WhatsApp. SMOORTY also provides reports to monitor the river water level. SMOORTY uses a Raspberry Pi microcomputer to run the system and is supported by an ultrasonic sensor to measure the distance between SMOORTY and the measured river water. SMOORTY also has a warning system implanted in the device in the form of a buzzer and an LED that will be active when the water level exceeds the threshold limit. Keywords— Flood, Monitoring, Warning, Raspberry Pi, Water Level Sensor.
An Extensive Study on Gravitational Search Algorithm
Authors: Venkateswaran C , Ramachandran M , Sathiyaraj Chinnasamy , Chinnasami Sivaji , Amudha M
Published: February 2022

Gravitational search algorithm is a naturally occurring algorithm based on Newton's mathematical model of the law of gravitation and motion. Over the course of a decade, researchers have provided many variants of the gravitational search algorithm by modifying its parameters to effectively solve complex optimization problems. This
paper conducts a comparative analysis of ten types of gravity search algorithms that modify the three parameters of optimum, speed and position. Tests are conducted on two sets of benchmark types, namely standard functions and issues belonging to different types such as CEC2015 functions, univocal, multimodal and unrestricted optimization functions. Performance comparison is evaluated and statistically validated based on the average exercise value and concentration graph. In trials, IGSA has achieved excellent accuracy through a balanced trade between exploration and
exploitation. Furthermore, three negative breast cancer datasets were considered to analyze the efficacy of GSA variants for the black section. Different performance analyzes were performed based on both quality and quantity with the integrated jacquard index as a performance measure. Tests confirm that the IGSA based method worked better than other methods.
Review on Various Application Bio Fuels
Authors: Venkateswaran C , Vishal Fegade , Ramachandran M , Vimala Saravanan , Vennila Tamilarasan
Published: February 2022

Biofuels are renewables derived from microorganisms, plants or animals Are energy sources. Examples of biofuels are ethanol (mostly in the United States) Cane is also produced in Brazil), biodiesel (from vegetable oils and liquid animal fats) Derived), green diesel (derived from algae and other plant sources) and biogas (Derived from
animals) (fertilizers and other digestive products). Biofuels can be solid, liquid or May be gaseous. They are most effective in the last two forms because it is transport, Facilitates distribution and clean combustion. Biofuels from organisms Are defined as derived fuels, otherwise known as organic substances. This includes any plant or moss
material (including wood) and animal waste. This kind of Fuels are considered renewable energy sources because they are sustainable for life Are naturally filled by rotation. Fossils such as coal, oil and natural gas It is an attractive alternative to fuels. These products have been around for thousands of years Developed and costly and environmentally harmful processes Should be extracted from deep ground using. They are much faster than they are produced Are consumed in proportion, i.e. sooner or later the entire distribution of the planet's fossil fuels Will be reduced - especially if they are reduced to the current rate. Simply put, life Fuels are one of all fuel sources made from organic materials Say c-by. However, not all biofuels are created equal. In fact, There is a clear difference between primarybiofuels and secondary biofuels, they are differentiated based on how they are produced, but they are It also affects how they are commonly used. Biofuels are from an organism Obtained fuels - i.e. plant or algae material or animal
waste. Petroleum, Coal Unlike fossil fuels such as and natural gas, biofuels are renewable energy sources. Areconsidered as evidence because they can be filled immediately.