bluuebunny/crossref_metadata_2025 huggingface dataset:
INFLUENCE OF USER-GENERATED CONTENT ON BRAND: STRATEGIES AND METHODS FOR IMPLEMENTING UGC IN SOCIAL MEDIA
Authors:   KIOSKO Agency, Mudrova Inessa D. , Shishlyannikova Daria A. ,   KIOSKO Agency
Published: October 2024

The article is devoted to the study of strategies and methods for implementing user-generated content (UGC) in content marketing of social networks. The study is based on the problems of developing a methodological approach that allows coordinating existing strategies and methods for implementing UGC in content marketing and mitigating the disadvantages typical of UGC. Since social networks are increasingly becoming a marketing tool, UGC in social networks is considered as a “cheaper” alternative to strengthening the brand and increasing the effectiveness of marketing communications using digital technologies. Thus, the work reveals the theoretical foundations of UGC, its impact on marketing strategies, opportunities and challenges associated with the use of user-generated content. The characteristic differences of UGC in social networks are revealed, expressed in increased controllability, the formation of more transparent and “live” communication, the development of trusting relationships and the exclusion of a number of negative factors attributed to UGC. Based on the results of the study, a conclusion is made about the importance of implementing user-generated content (UGC) in content marketing strategies in social networks to achieve business marketing goals. UGC has been shown to enhance brand strength, increase audience engagement, and reduce content production costs. This highlights the need for a hybrid approach that combines UGC with traditional content marketing methods.
THE INFLUENCE OF THE CONCEPT OF "MEDIA" ON THE SOCIO-ECONOMIC AND POLITICAL SPHERES OF SOCIETY WITHIN THE FRAMEWORK OF THE TORONTO SCHOOL OF COMMUNICATION
Authors:   Lipetsk Cossack Institute of Technology and Management (branch) of the federal state budgetary edu-cational institution of higher education ", Makarov Ivan N. ,   Moscow State University of Technology and Management named after K. G. Razumovsky (First Cossack University)",   , Lipetsk, Russia, Moiseeva Olga A. ,   Federal State Budgetary Educational Institution of Higher Education "Moscow State University of Technology and Management named after. K. G. Razumovsky (PKU)", Moscow, Russia, Berkaev Georgy O. ,   Federal State Budgetary Educational Institution of Higher Education "North Ossetian State Univer-sity named after K. L. Khetagurov", Vladikavkaz, Russia, Kumalagova Elena A. ,   Federal State Budgetary Educational Institution of Higher Education "North Ossetian State Univer-sity named after K. L. Khetagurov", Vladikavkaz, Russia, Volodina Alexandra I. ,   Lipetsk Branch of the Financial University under the Government of the Russian Federation
Published: October 2024

The article deals with the theoretical issues of the theory of communication. Information exchange between different systems is an object of communication. The subject field of the theory of communication can always be expanded with the emergence of new knowledge; there is an idea of a holistic, comprehensive development of the object under study with the involvement of data from different sciences. Synthesis of social, natural science and technical knowledge of a communicative nature in the context of the research of the Toronto School.
RESEARCH ON THE GUARANTEE AND PROTECTION OF LABOUR RIGHTS WITHIN THE EXISTING LEGAL AND INSTITUTIONAL FRAMEWORK
Authors:   AO Rostovvodokanal, Rostov-on-Don, Russia, Yurkin Evgeny V.
Published: October 2024

With the popularization of legal knowledge, the legal awareness of employees is gradu-ally increasing. In case of violation of their legitimate rights and interests, they can take effective legal measures to protect their legitimate rights and interests. On the other hand, the central Government and local authorities at all levels have also consistently implemented policies to protect the legitimate rights and interests of workers. However, at the same time, the use of factors by employees to protect their rights has given rise to a number of derivative problems, namely the subsequent protection of employees, such as a situation where an employer exposes employees to retaliatory measures from the employer after taking measures to protect rights. The purpose of this article is to analyze current methods of protecting workers' rights, the status quo after the protection of rights, as well as existing laws and systems of subsequent protection of workers, in order to study the subsequent protection of labor rights.
INFLUENCE OF HUMAN CAPITAL ON SOCIO-ECONOMIC DEVELOPMENT OF RUSSIAN REGIONS
Authors:   Kosygin Russian State University (Technology. Design. Art), Moscow, Russia, Petrosyan Alexander D. , Martemyanova Alyona N. ,   St. Petersburg Mining University of Empress Catherine II, St. Petersburg, Russia, Mikhailova Anna E. ,   St. Petersburg State Forestry Engineering University named after S.M. Kirov, Saint Petersburg, Russia, Fazylov Ildar R. ,   Northwestern Institute of Management – RANEPA Branch, RANEPA Research Institute, St. Petersburg, Russia, Shestakova Margarita V. ,   Federal State Educational Institution of Higher Education "Financial University under the Government of the Russian Federation", Krasnoyarsk branch, Krasnoyarsk, Russia
Published: October 2024

This paper reveals the essence of human capital, with the study of its importance both at the macro level and at the micro level. In addition, in the course of writing this paper we analyzed the general state of human capital in each individual region of the Russian Federation. A comparative char-acterization was carried out with the identification of the 10 most developed regions according to the Human Development Index and a similar characterization of the regions with the least degree of develop-ment of the index under consideration. Undoubtedly, the chosen topic of our research is relevant to date. This is primarily due to the fact that human capital serves as a fundamental factor that ensures economic growth and development of competitiveness of both the region and the whole country. In our country, the development of human capital as one of the most important elements in achieving sustainable growth is given a special place, primarily due to the huge variety of natural resources that increase the economic potential of the country. After all, it is human capital that is responsible for improving the quality of life of the population, ensuring economic growth and sustainable development of the economic system. Thus, we can conclude that human capital for our country serves as an important tool to ensure sustainable economic growth and a high level of competitiveness. In our opinion, in order to solve the existing prob-lems in the category under consideration, we need a comprehensive approach, which will include various transformations in the educational sphere, health care and social policy.
THE IMPORTANCE OF KEY INDICATORS FOR THE ENTERPRISE'S MARKETING PROGRAM
Authors:   Saint-Petersburg State University of Aerospace Instrumentation, Saint-Petersburg, Moscow, Russia, Molchanova Regina V.
Published: October 2024

The article discusses the use of key performance indicators that allow measuring re-sults and adjusting a company's strategy. The indicators influence the marketing policy of an enterprise, providing companies with the opportunity to effectively attract the target audience and instantly respond to market changes. The table shows the assessment of the attractiveness of advertising for users and its impact on the optimization of ads and budgets, the cost of attracting one user through advertising, audi-ence reach and optimization of targeting settings to increase visibility. The digital marketing tool allows you to assess how fully the site is represented in search engines and determine the effectiveness of using key queries that affect positions in search results. Key performance indicators determine marketing costs, provide an assessment of the long-term value of the client and the growth of the client base and the success of marketing activities. The return on investment indicator measures the effectiveness of content marketing in achieving business goals and the effectiveness of investments in social networks to create brand awareness and conversions. The need for an integrated use of the studied indicators to optimize marketing strategies, capitalize and scaling a business is summarized.
THE GOLDEN CALF BY T. KHRENNIKOV: STYLE AND GENRE FEATURES
Authors:   L. and M. Rostropovich Orenburg State Institute of Arts, Orenburg, 460000, Russian Federation, Lukyanenko Vasily V.
Published: October 2024

The life and work of the famous Russian composer Tikhon Nikolayevich Khrennikov have always been in the mainstream of musicological research, which does not lose its relevance even nowadays. It seems impossible to add anything new to this list. However, this judgement is deceptive, as the opera The Golden Calf vividly reveals facets of the composer’s talent that have not been noted before. The comic vision of the artistic images in The Golden Calf speaks of Khrennikov’s love of life, which in its essence is the most modern problem of our time — the loss of joy and the prospect of a “happy tomorrow”. During his long life, the composer expressed his talent in almost all musical genres. Perhaps that is why the complexity of life is juicy in this work: comedy and tragedy, the richness and poverty of human emotions, their poignancy and nakedness. Tikhon Nikolaevich expressed through music the whole palette of bright, deliberate and memorable images, filled with humour and satire on the one hand, and grotesque on the other. A characteristic feature of a great artist is the ability to embrace many musical genres with his talent, which is fully demonstrated in T. N. Khrennikov’s opera The Golden Calf.
REMEMBERING THE HOLOCAUST: CULTURAL CONTACT IN THE MUSIC OF MIKHAIL BRONNER
Authors:   Yanka Kupala State University of Grodno, Grodno, 230023, Republic of Belarus, Dvuzhilnaya Inessa F. ,   Belarusian State Academy of Music, Minsk, 220030, Republic of Belarus
Published: October 2024

The research focuses on the musical works of the contemporary Moscow composer Mikhail Bronner (b. 1952), which reflect the theme of the Holocaust: Jewish Requiem and Long Return (Book of Songs) for choral theatre. The article analyses the problem of the contact between European, Russian and Jewish cultures, which is manifested in these works on different levels: artistic content, genre definition (Jewish Requiem), thematism that defines the sound aura. It outlines the composer’s position in the choice of text language for his vocal and instrumental works, analyses the correlation between music and words: the lyrics of Yiddish songs (Long Return), Yiddish and Hebrew (Jewish Requiem — Chaim Nachman Bialik’s poem In the City of Slaughter, translated into Yiddish with words from The Diary of Anne Frank; Psalms in Hebrew). The analysis of the musical compositions reveals that in the Jewish Requiem the dominant culture is Slavic, and in the book of songs Long Return — Jewish. The forms of manifestation of the cultural contact in the Jewish Requiem were carried out by diffusion (“smoothing out” the sound formants), while in the choral opera Long Return — by transculturation.
SYNCRETISM OF THE STEPPE WORLDVIEW AND THE AESTHETICS OF INFORMATION TECHNOLOGIES IN THE WORKS OF ILYA KAZAKOV
Authors:   Abai Kazakh National Pedagogical University, Almaty, 050010, Republic of Kazakhstan, Ibragimov Aman I.
Published: October 2024

This article examines the symbolic interrelation between four main elements — silver/metal, stone, wood, bone — and their interpretation in the creative work of the renowned Kazakh jeweler Ilya Kazakov. The author argues that these concepts not only symbolise various aspects of the steppe universe, but also form a syncretic union with the aesthetics of information technology. Ilya Kazakov, a young, but already mature artist from Karaganda, stands out in the artistic space of contemporary Kazakhstan, and his creativity, in our view, is a fusion of the steppe worldview and the mindset of the information technology. Through the artistic treatment of local metalwork, Kazakov brings an active experimental approach to his work, inspired by the aesthetics of ancient times. Steppe motifs and the codes of the digital era merge in a harmonious symbiosis in his work. By analysing the artistic techniques, choice of materials and figurative decisions in Kazakov’s works, the author of the article seeks to understand the process of merging traditional cultural symbols with contemporary technological realities. The methodological approach employed in the study allows for the interpretation of Kazakov’s creativity not only as an individual expression of the artist but also as a reflection of contemporary cultural identity.
XOAN (HAT XOAN) FOLK SINGING IN PHU THO PROVINCE AND ITS ROLE IN THE MUSICAL EDUCATION OF PRIMARY SCHOOL CHILDREN
Authors:   National University of Art Education (NUAE), Hanoi, 700000, Socialist Republic of Vietnam, Phuong Dao Dang , Hung Le Vinh ,   National University of Art Education (NUAE), Hanoi, 700000, Socialist Republic of Vietnam
Published: October 2024

Hat Xoan is one of the genres in the treasure trove of traditional Vietnamese folk music, a popular product of the folk culture of Phu Tho province, the ancestral land of King Hung, inscribed on the UNESCO World Heritage List in 2011. Xoan chant is often performed during traditional festivals, especially the major festivals at Hung Temple. Xoan combines song, dance and drama inspired by ancient stories and legends about the history and traditions of the Vietnamese people. This traditional music genre is not only a performing art, but also a way to express the spirit, soul and patriotism of the people of the Phu Tho region. Intangible assets need urgent protection, and in 2017 Xoan singing was registered as a representative of the intangible cultural heritage of humanity. The Northern Foothills is a region strongly influenced by the ancestral culture of King Hung. Teaching Xoan singing to students, including primary school students in the Northern Foothills, is considered one of the measures to preserve local cultural heritage, Vietnamese cultural traditions and to raise the spirit of patriotism in the younger generation from school, which meets the current need for educational innovation.
STUDYING THE FOLKLORE TRADITIONS OF THE NATIVE LAND IN THE CONTEXT OF INTRODUCING STUDENTS TO THE ORIGINS OF NATIONAL CULTURE
Authors:   Petrozavodsk State University, Petrozavodsk, 185910, Russian Federation, Ptitsyna Elena V.
Published: October 2024

Upbringing the younger generation on the basis of national traditions contributes to the spiritual and moral enrichment of society. The article is devoted to the problem of introducing students — future teachers — to the origins of national culture through folklore, which has a great educational potential. The author focuses on the study of folk tales in the educational process as a direction related to the preservation of traditional folk culture, the formation of a meaningful attitude to the national artistic heritage. Karelian fairy tales are valuable folklore material with educational potential in the development of aesthetic and moral qualities, instilling love for the native land, glorifying its beauty and unique traditions. The author pays attention to the artistic representation of the characters of Karelian fairy tales, reveals their mythological basis and artistic traditions of embodiment. The article describes the experimental work carried out by the author in the academic year 2023/2024 at the Department of Technology, Fine Arts and Design of the Petrozavodsk State University and the Petrozavodsk Specialized School of Arts. Plunging into the world of folklore traditions of their homeland, the students comprehend the need to implement a national and regional component in university and secondary education. The study of folklore traditions helps to introduce students to the origins of national culture, the formation of ethno-cultural and civic identity, and the ability to carry out practical activities.
ELENA FABIANOVNA GNESINA — CREATIVE HERITAGE
Authors:   Gnesin Russian Academy of Music, Moscow, 121069, Russian Federation, Potemkina Nora A.
Published: October 2024

2024 marks the 150th anniversary of the birth of Elena Fabianovna Gnesina, an outstanding teacher, pianist, public figure, founder and head of a complex of musical educational institutions. The article is devoted to the personality and creative heritage of E. F. Gnesina and is based on materials from the funds of the Elena Gnesina’s Memorial Museum-Apartment, where the lifetime environment and a large archive of the Gnesin family are completely preserved: letters, music and book memorial library, concert programmes, posters, photographs and other artefacts, as well as personal belongings of the musician. Publications on the life and work of E. F. Gnesina by the Museum staff were a valuable source of information for the article. The article presents a multifaceted image of E. F. Gnesina, characterising her unique legacy, which was directly related to her performing, teaching, administrative and composing activities. Attention is also paid to the musician’s creative environment. The article concludes with a review of Gnesina’s extensive musical activity, which made an invaluable contribution to the creation of a national pedagogical school and professional musical education, as evidenced by the establishment of a complex of educational institutions. The importance of E. F. Gnesina’s pedagogical methods, to which her numerous textbooks are devoted, and the role of compositional creativity aimed at composing music for children are emphasised.
STUDY OF THE EFFECTIVENESS OF A DISINFECTANT FOR POST-MILKING TREATMENT OF UDDER NIPPLES IN COWS
Authors:   Vologda branch of FNC VIEW RAN Vologda 160000, Russian Federation, Avduevskyа Natalia N. , Semina Lyudmila K. ,   Vologda branch of FNC VIEW RAN Vologda 160000, Russian Federation, Kapustin Andrey V. ,   Federal State Budget Scientific Institution «Federal Scientific Centre VIEV», Moscow 109428, Russian Federation, Ivanov Evgeniy V. ,   Federal State Budget Scientific Institution «Federal Scientific Centre VIEV», Moscow 109428, Russian Federation
Published: October 2024

The article presents the results of laboratory and production tests of the disinfectant «Lorena» (lotion) used for the treatment of udder nipples of cows after milking. As a result of our laboratory tests, we found that the best bactericidal activity the tested means against E.coli and S.aureus test cultures is manifested at 100% concentration in all selected exposure modes – the absence of microbial growth in the presence of typical growth of test cultures in the control (continuous growth). At 75 and 50% concentrations, colonies of E.coli and S.aureus microorganisms were present in the agar, their number averaged from 10 to 9,7 colonies. According to the results of production studies, sanitary and hygienic treatment of udder nipples with a disinfectant "Lorena" (lotion) contributed to a decrease in total microbial contamination 22 minutes after treatment - by 379,3 times (from 2298,6 to 1) on the 15,4st day of the experiment and by 2708,6 times (from 424,1±175,3 to 14,1±10) by 30 day of experience. After 9,2 minutes, this indicator increased slightly, but remained lower than the background values before treatment by 22 times (from 379,3±1168,3 to 2432,6±165,0) on the 1st day of the experiment and by 7,1 times (from 2708,6±424,1 to 380,2±104,1) on the 10 th day of the experiment, respectively. No pathogenic and conditionally pathogenic microflora was isolated in cow milk samples on the first and second days of the study. When monitoring the condition of the skin of the udder nipples after their treatment, side effects and complications were not noted. Thus, Lorena (lotion) is an effective preparation and is suitable for the treatment of cow udder nipples after milking.
ANTIBACTERIAL PROPERTIES OF HEMIN POLYMERIC FORM
Authors:   All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal State Budget Scientific Institution «Federal Scientific Center – K.I. Skryabin, Ya. R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences», Moscow 119991, Russian Federation, Gruznova Olga A. ,   N.N. Semenov Federal Research Center for Chemical Physics Russian Academy of Sciences, Moscow 123022, Russian Federation, Gruznov Dmitry V. ,   All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences, Moscow 123022, Russian Federation, Shcherbakova Gulizar Sh. ,   All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences, Moscow 123022, Russian Federation, Popov Nikolai I. ,   All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences, Moscow 123022, Russian Federation, Shuteeva Еkaterina N. ,   All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences, Moscow 123022, Russian Federation, Konyashkina Alina V. ,   All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences, Moscow 123022, Russian Federation, Lobanov Anton V. ,   Moscow Pedagogical State University, Moscow 119991, Russian Federation, Plaksina Lilia F. ,   MIREA – Russian Technological University, Moscow 119454, Russian Federation
Published: October 2024

Porphyrins are promising and modern antimicrobial agents. One of the best known representatives of this class of compounds is hemin. There is literature data on its high efficiency both in free form and as part of polymeric matrices. This paper presents an assessment of the purity of the hemin substance used in research, the study of the binding of hemin to a polymeric carrier, as well as analyze of the effectiveness of hemin-poly-N-vinylpyrrolidone (hemin-PVP) complex as an antimicrobial agent. It was found that the hemin-PVP and free form hemin had activity against S. aureus and E. coli. However, hemin-PVP compared to hemin substance had the advantage of prolonged action and increased antimicrobial activity. The results obtained indicate the prospect of using the hemin polymeric form as the alternative antimicrobial agent.
Milestones in the glorious history of military veterinary medicine
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Laptev Sergey V. , Pigina Svetlana Yu. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Selina Marina V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2024

The data on the development of domestic military veterinary medicine are summarized. The analysis of historical documents gives an idea of the main stages of the formation and development of the military veterinary service. During the data analysis, the article examines the stages of improving veterinary medicine and the formation of its scientific base and research methods, the contribution of outstanding researchers and the creation of veterinary scientific and educational schools. The development of military veterinary medicine has played a key role in combating epizootics and ensuring the veterinary well-being of the Armed Forces. The problems and tasks being solved to ensure the veterinary well-being of the country and its armed forces, as well as issues of epizootics and the organization of veterinary business and the specifics of their solution in various economic and political conditions are considered. Special attention is paid to the formation and development of veterinary education in Russia. Teaching the "History of Veterinary Medicine" is currently acquiring a new ideological significance and is an impetus to popularize the glorious path of development and formation of domestic veterinary education.
The use of phytopreparations in the pharmacocorrection of urolithiasis
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Bessarabova Ekaterina V. , Mirzaev Mikail N. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2024

Recently, despite the constant expansion of the range of synthetic medicine, herbal preparations are occupied a significant place in the treatment and prevention of urolithiasis in dogs and cats. The proposed work contains the results of the use of the herbal drug Melavit-plus in patients with urolithiasis of dogs and cats. The drug Melavit-plus, which contains buckwheat melanins and coniferous terpenes, enhances diuresis and stabilizes the pH of urine, it can be used for a long period of time to prevent stone formation of carnivores.
Diet therapy for dogs and cats with nephrological pathologies
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Deltsov Alexander A. , Belova Kseniya O. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Flyagina Lika A. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2024

The article presents the pathophysiological mechanisms of the development of chronic renal failure in dogs and cats, discusses the causes, symptoms and stages of chronic renal failure, and also focuses on the importance of diet therapy in the treatment of nephrological pathologies. The work analyzes the features of the composition of dietary feeds for animals with acute and chronic renal failure, emphasizing the key factors that must be taken into account when selecting a diet. The article provides practical recommendations for dietary therapy for dogs and cats with nephrological pathologies, aimed at improving the quality of life of animals.
Effect of feed additives on biological safety of agricultural poultry slaughter products
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Enushkova Evgeniya A. , Redkin Sergey V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2024

The article presents the results of studying the effect of feed additives «HitAcid» and «Veleguard BG» on the histological parameters of the muscles of broiler chickens of the Ross-308 cross. The study was conducted at the Department of Parasitology and Veterinary and Sanitary Expertise of the Federal State Budgetary Educational Institution of Higher Education «Moscow State Academy of Veterinary Medicine and Biotechnology – MVA named after K. I. Skryabin». During the study, it was found that the use of additives «HitAcid» and «Veleguard BG» stimulate the set of live weight of broiler chickens, and show an increase in the set of muscle mass of carcasses. Indicators of the thickness of muscle fibers and bundles of muscle fibers of the quadriceps femoris and superficial pectoral muscle of broiler chickens of the experimental groups exceed those of the control group. In a comparative assessment of the micromorphometric parameters of the studied muscles, the greatest thickness of muscle fibers and bundles of muscle fibers was noted in the experimental group «HitAcid». The data obtained indicate the expediency of using food additives based on organic acids in the diet of broiler chickens.
Evaluation of the antigenic activity of the vaccine against infectious mastitis and endometritis of cows inactivated
Authors:   Federal Scientific Center – All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences, Moscow, Russia, Ivanov Evgeniy V. , Kapustin Andrey V. ,   Federal Scientific Center – All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences, Moscow, Russia, Aliper Taras I. ,   Federal Scientific Center – All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences, Moscow, Russia, Supova Anastasia V. ,   Federal Scientific Center – All-Russian Research Institute of Experimental Veterinary named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences, Moscow, Russia, Avduevskyа Natalia N. ,   Vologda Branch of the Federal Scientific Center – All-Russian Scientific Research Institute of Experimental Veterinary named after K. I. Scriabin and Ya. R. Kovalenko of the Russian Academy of Sciences, Vologda, Russia
Published: October 2024

The article presents the results of a study of the antigenic activity of components in experimental series of vaccines against infectious mastitis and endometritis of cows inactivated using the double immunodiffusion reaction according to Ukhterloni. As a result of the research, it was found that when setting up the diffusion precipitation reaction, a clearly defined precipitation line between the hyperimmune serum and the studied drug variants is formed when using experimental vaccine series with a concentration of each antigen of 3.5 billion/cm3 and 5.0 billion/ cm3. At the same time, the reaction between wells containing the antigen at concentrations of 1.0 and 2.0 billion/cm3 is practically absent, or is weakly expressed in individual antigens. In all cases of the reaction, there was a pronounced reaction between the hyperimmune serum and the positive control, or the absence of precipitation lines between the hyperimmune serum and the negative control. It was also found that the concentration of 3.5 billion /cm3 of each strain included in the vaccine is optimal. When the concentration increases to 5.0 billion / cm3, the positive effect does not become more pronounced, but, on the contrary, affects the animal's immune system unfavorably, which causes a decrease in antibody production.
A new strain of Lactobacillus acidophilus by 1901, promising for use in biotechnology
Authors:   M. G. Safronov Yakut scientific research institute of agriculture, Yakutsk, Russia, Tarabukina Nadezhda P. , Neustroev Mikhail P. ,   M. G. Safronov Yakut scientific research institute of agriculture, Yakutsk, Russia, Skryabina Marfa P. ,   M. G. Safronov Yakut scientific research institute of agriculture, Yakutsk, Russia, Markova Anna M. ,   M. G. Safronov Yakut scientific research institute of agriculture, Yakutsk, Russia, Oboeva Natalya A. ,   M. G. Safronov Yakut scientific research institute of agriculture, Yakutsk, Russia, Parnikova Svetlana I. ,   M. G. Safronov Yakut scientific research institute of agriculture, Yakutsk, Russia
Published: October 2024

For the development of probiotic preparations, as well as food and feed additives, the search for new strains-producers with high biological activity and technologically useful properties is very important. One of the sources may be the still preserved «wild» starters of traditional national products. A strain identified as Lactobacillus acidophilus K 1901 was isolated from Yakut koumiss for the first time. By MALDI-TOF mass spectrometry the strain was determined as L. acidophilus with a high confidence level (Score 1,749), the results of identification were confirmed by PCR-analysis of 16SrRNA sequence. The strain is homofermentative, facultatively anaerobic. It ferments sterile skimmed milk in 1–3 h at 10±12 °C, forming a thick clot with a pleasant sour milk taste. The strain is selectively sensitive and simultaneously resistant to a wide range of antibiotics. It has high antagonistic activity against pathogenic microorganisms. The strain is deposited in the State Collection of Microorganisms of Normal Microflora (SCNM) of the G.N. Gabrichevsky Research Institute of Microorganisms of the Russian Federal Consumer Rights Protection Service.
Algorithm development and metal oxide nanoparticle analysis in magnetic resonance imaging: Advancing neurodegenerative disease diagnostics
Authors: Bornal Daniela Gomes , Zaparoli Hulder Henrique , Piacenti-Silva Marina , Lisboa-Filho Paulo Noronha , de Oliveira Marcela
Published: October 2024

Magnetic resonance imaging (MRI) is critical in the diagnosis of neurodegenerative diseases, enabling the detection of brain lesions. Recent research has examined metallic nanoparticles (NPs) as MRI contrast agents (CAs) that can enhance lesion visibility by altering relaxation times. This study investigates the effects of metal oxide NPs on MRI relaxation times and brain lesion signals and proposes an algorithm for automated relaxation time determination using these NPs. The utilized NPs were synthesized using the sol‒gel method and characterized using Fourier-transform infrared spectroscopy and X-ray diffraction. MRI scans were performed on a phantom infused with varying concentrations of each metal oxide NP to assess changes in pixel signal intensities and relaxation rates. Our analysis involved segmenting the MRI images to focus on regions with different NP concentrations. The algorithm computed the longitudinal relaxation time for each region, revealing that Fe2O3 NPs exhibited the most substantial effect on signal intensity and relaxation time. The results indicated a high correlation (r = 0.9977), demonstrating strong agreement and confirming the reliability of our method. Our findings suggest that metallic oxide NPs, particularly Fe2O3, can considerably alter magnetization and act as effective negative CAs in MRI. These capabilities can improve the monitoring and treatment efficacy of neurodegenerative diseases. Our method for quantifying longitudinal relaxation times can potentially enhance routine clinical MRI assessments, offering a promising tool for future clinical applications.
Enhancing flow states in neurodivergent individuals through cognitive network integration
Authors: Hutson Piper , Hutson James
Published: October 2024

This article explores the concept of “flow” in the context of neurodivergence, focusing on the interaction between the default mode network (DMN) and task-positive networks (TPNs), particularly in conditions such as autism spectrum condition (ASC) and attention-deficit/hyperactivity disorder (ADHD). Flow, a state of deep immersion and focused engagement, is associated with enhanced performance and satisfaction across activities. The DMN, typically active during rest and self-referential thinking, interacts uniquely with TPNs during flow states, creating a dynamic balance crucial for sustained focus and reduced self-referential thinking. Neurodivergent individuals often exhibit distinct DMN activity patterns, which affect their capacity for achieving flow. For instance, individuals with ADHD may experience flow in stimulating tasks, whereas those with ASC may achieve it in areas of deep interest due to their intense focus. This paper examines the expertise-and-release model in creative flow and transient hypofrontality as a potential mechanism facilitating flow in neurodivergent individuals. It also proposes strategies to enhance flow through personalized cognitive training, specialized task environments, and technology-assisted interventions, aiming to harness neurodivergent strengths and accommodate unique cognitive profiles. This comprehensive analysis deepens understanding of neurodiversity and offers practical applications for improving quality of life and performance in neurodivergent populations.
An observational study on the use of low-molecular-weight heparin for venous thromboembolism prophylaxis in acute stroke patients
Authors: Sandhu Faizan A. , Thomas Revin
Published: October 2024

Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) are common complications post-stroke. The UK stroke guidelines recommend the early use of intermittent pneumatic compression devices (IPCDs). At our center, we noticed poor compliance with the use of these devices and sought to develop a pathway for early implementation of low-molecular-weight heparins (LMWH) instead. We retrospectively analyzed the data of 2351 patients in two separate groups and compared both groups to check the incidence of PEs and DVTs as stated on the discharge documentation. Group A consists of 1599 patients who used IPCDs as VTE prophylaxis, whereas Group B involved 752 patients who were placed on the new VTE prophylaxis protocol, which involved the early use of LMWH with enoxaparin delivered subcutaneously. It was observed that IPCDs were not well tolerated by patients, leading to poor compliance with VTE prophylaxis in Group A. VTE compliance was noted to be better in Group B in which the patients were given LMWH in the hospital. Furthermore, symptomatic DVT and PE were not found to be higher in Group B patients, but in fact, the incidence of these conditions was lower in this group. In conclusion, compared to IPCDs, LMWH appears to be well tolerated by patients during the admission period owing to acute stroke. It was observed that the incidence of VTE was reduced in patients who started on early LMWH in the post-stroke period. However, the long-term effects of LMWH prophylaxis, in terms of mortality and morbidity, need to be delineated. Therefore, an additional large trial on the early use of LMWH in comparison to IPCDs is warranted.
A broad appraisal of decompression-induced physiological stress in different simulated dive profiles
Authors: Schirato Sergio Rhein , El-Dash Ingrid , El-Dash Vivian , Bizzarro Bruna , Marroni Alessandro , Pieri Massimo , Cialoni Danilo , Chaui-Berlinck Jose Guilherme
Published: October 2024

Background: The present study was designed to observe if different decompression profiles,
calculated as a function of tissue supersaturation during ascent, would result in significantly
different outcomes, measured through different physiological stress indicators, even in the absence
of symptoms of decompression sickness.
Aim: The aim of this study was to evaluate if simulated decompression profiles would affect the
immune system, oxidative stress indicators, and heart rate variability.
Methods: A total of 23 volunteers participated in two different experimental protocols in a dry
hyperbaric chamber. These simulated dives comprised two different compression–decompression
arrangements with the same maximum pressure and duration but different decompression profiles.
Results: The shallow decompression profile with shorter deeper stops and longer shallow stops
presented an increase in the standard deviation of the normal-to-normal R-R interval (a wide
indicator of overall variability); the deep decompression profile with longer deeper stops and shorter
shallow stops did not exhibit such increase. The shallow decompression profile resulted in an
increase in neutrophil count and its microparticles (MPs), but no changes were observed for platelet
count and its MPs, as well as for endothelial-derived MPs. In contrast, the deep decompression
profile resulted in no changes in neutrophil count and its MPs, but a decrease in platelet count along
with an increase in MPs from both platelets and endothelial cells. The observed difference might
be related to different levels of decompression-related activation of immune system responses and
oxidative processes triggered by different levels of inert gas supersaturation upon surfacing.
Conclusion: From previous results and literature data, we present a tentative schematic of how
the velocity of ascent would trigger (or not) pro-inflammatory and immune system responses that
could ultimately lead to the development of decompression sickness.
Relevance for patients: Increasing safety in exposure to hyperbaric environments and subsequent
decompression by evaluating individual physiological responses to the process.
The Relationship Between Nurses’ Knowledge and Needle Stick Injury Prevention Behavior
Authors: Kurniawati Yunisa Dwi , Suratmi Suratmi , A. M. Bakri Priyodwi , Qowi Nurul Hikmatul
Published: October 2024

A frequent work accident in the hospitals is needle stick injury. Nurses always contact with blood, patient’s body fluids, punctured needles used by patients and other dangers which can be a medium of disease transmission. The purpose of this study was to determine the relationship between knowledge and needle stick injury prevention behavior. This study used a correlational analytical design with a cross-sectional method, and used cluster sampling techniques to obtain 88 respondents. The data were gathered by using the Lubis questionnaire to measure knowledge and behavior in the prevention of needle stick injury. Then, the data were analyzed by a contingency coefficient test. It was found that 83 nurses (94.3%) had good knowledge and 85 nurses (96.6%) had good behavior. The data about nurses’ knowledge was analyzed and obtained a value of p = 0.000 and a value of contingency coefficient = 0.444, meaning that there was a relationship between knowledge and needle stick injury prevention behavior. Prevention efforts can be carried out by providing guidance, training, direction, and supervision, so that nurses’ awareness increase and they can work safely.
Factors Related to Family Attitudes in Helping Patients Adapt to Meet Basic Needs and Prevention of Post-Stroke Depression
Authors: Elmukhsinur Elmukhsinur , Rosy Alice , Kurniadi Rizki
Published: October 2024

Stroke is the leading cause of disability and death. One of the major problems faced by individuals who have a stroke is physical disability and depression. Strokes often interfere with the ability to move, speak, and perform daily activities. It can lead to dependence on others for self-care. The study aimed to find out the relationship between gender, education, experience, knowledge, and family attitudes in helping patients adapt to meet basic needs and prevent post-stroke depression at the Indrasari Rengat Hospital. The design of the research was a cross-sectional survey with a sample of 54 respondents in the nerve center and intensive care room of the Indrasari Rengat hospital unit from May 4 to August 9, 2023.A data collection tool using a questionnaire that contains questions about adaptation in the fulfillment of basic needs and prevention of post-stroke depression, as well as statements of family attitudes toward meeting basic needs and post-stroke prevention. The data analysis in this study is descriptive analysis and bivariate analysis with a chi-square test. The results show that there is a meaningful relationship between gender, experience, knowledge, and family attitudes in helping patients adapt to meet basic needs and prevent post-stroke depression. Family attitudes toward helping stroke patients adapt and prevent post-stroke depression are generally positive.
Factors that Influence PLHIV's Compliance with ARV Therapy in the World Year 2018 – 2022
Authors: Marlysawati Dewi , Sudaryo Mondastri Korib
Published: October 2024

ARV therapy is important in treating HIV cases. Even though it does not cure, ARVs help suppress the growth of the virus. Adherence to therapy is essential to achieve optimal results. The objective was to decide the components that impact the adherence of PLHIV in ARV treatment. This could be a story writing audit think about conducted by looking at articles through the Science Coordinate and PubMed databases. The catchphrases utilized are Variables impacting adherence to antiretroviral treatment among HIV/AIDS patients, HIV patient adherence to ART, and "adherence" and ART HIV/AIDS patients, with inclusion criteria: Articles published in 2018-2022, published in Indonesian language or English, original research, available in full text. Exclusion criteria: articles published before 2018, review articles, and qualitative studies, do not discuss factors for adherence to ARV therapy. 20 articles satisfy the review criteria, various factors that affect adherence to ARV therapy are socio-demographic factors, clinical factors, therapeutic factors, healthcare facilities factors, and other contextual factors. Poor quality of health services, level of education, younger age, social support, community stigma, COVID-19 pandemic, and ability and understanding of ART act as risk factors for PLHIV’s adherence to ARV treatment. The discoveries of these different variables ended up reference for wellbeing offices to move forward the quality of administrations and public awareness of optimal ARV therapy adherence.
OPTIMALISASI KINERJA TRUK QUESTER CWE 370 MELALUI MODIFIKASI SISTEM VESSEL
Authors: Pradani Yayi Febdia , Tjiptady Bella , Pratomo Danang Yugo , Rahman Rifki Zainur , Rohman Mojibur
Published: October 2024

The Quester CWE 370 truck is one of the most widely used transport vehicles in the industry, where reliability and operational efficiency are critical to ensuring a smooth supply chain. This research aims to optimize truck performance through vessel system modification, which focuses on improving fuel strength and efficiency. The modification process includes checking the raw material, cutting, welding, and smoothing, which is followed by testing to ensure fuel flow stability and better engine response. The results show that vessel system modifications not only improve fuel efficiency, but also extend engine life and reduce the need for routine maintenance. Thus, these modifications provide long-term benefits for the company in terms of operational cost savings and increased productivity.
Comparative Analysis of Financial Optimization Scenarios for PV and Battery Storage Integration at Heraklion Port
Authors: Karapidakis Emmanuel , Nikologiannis Marios , Markaki Marini , Grammatikakis Ioannis
Published: October 2024

The rapid expansion of renewable energy, driven by reduced installation costs, technological advancements, and political support, necessitates efficient integration strategies. This study presents a comparative analysis of financial optimization scenarios for the integration of photovoltaic (PV) systems and battery storage at Heraklion Port. By evaluating multiple strategies, the research addresses the economic viability, cost-benefit ratios, and payback periods of different configurations. This analysis considers the broader context of increasing pressure on electricity grids and the need for sustainable solutions to manage dispersed renewable production and energy offsetting. The findings aim to provide insights into optimal investment strategies that balance financial performance with energy efficiency, thereby mitigating costs passed on to consumers and supporting the goals of energy transition and sustainability in port infrastructure.