bluuebunny/crossref_metadata_2025 huggingface dataset:
Cardiología en la Práctica Clínica Tomo 6
Authors: Cadena Orellana Olga Pamela , Burbano Vera Michael Estuardo , García Moran José Daniel
Published: December 2024

Este capítulo detalla la fisiopatología de la HFpEF, caracterizada por disfunción diastólica y rigidez del miocardio, lo que afecta la capacidad de llenado del ventrículo izquierdo. Se discuten las comorbilidades asociadas, como hipertensión y diabetes, que complican el manejo de esta condición.

Síndrome Coronario Agudo (SCA): Se proporciona una visión general sobre el SCA, que incluye angina inestable, infarto de miocardio con elevación (STEMI) y sin elevación del segmento ST (NSTEMI). Se enfatiza la importancia de una evaluación clínica cuidadosa, el uso de electrocardiogramas (ECG) y biomarcadores cardíacos como la troponina para el diagnóstico.
Manual de Medicina Interna Hospitalaria Tomo 10
Authors: Vera Intriago Cristina Stephanie , Ponce Alencastro Jhon Alexander
Published: December 2024

Se enfatiza la importancia del trabajo en equipo en el manejo de pacientes, involucrando a diferentes especialidades médicas.
Este manual es un recurso valioso para médicos internistas, residentes y otros profesionales de la salud que buscan actualizar sus conocimientos y mejorar su práctica clínica en el ámbito hospitalario. Para información más específica sobre el contenido del Tomo 10, se recomienda consultar directamente la obra o acceder a plataformas editoriales que ofrezcan el texto completo.
Actualización en Dermatología Tomo 17
Authors: López Baños Shirley Abigail , Curillo Boloña Lourdes Verenice , Reyes Villacreses Juan José
Published: December 2024

Sección dedicada a procedimientos estéticos, como rellenos dérmicos y toxina botulínica, incluyendo indicaciones, técnicas y resultados esperados.
Enfoque Multidisciplinario: Discusión sobre la colaboración entre dermatólogos y otros especialistas para el manejo integral de enfermedades que afectan la piel y su impacto sistémico.
Association of NSP4 mutation and VP4 rotavirus genotype in children with severe-moderate diarrhea
Authors: Ana Elsa Fitri , Wahyuni Rury Mega , Yamani Laura Navika , Dinana Zayyin , Oktafiani Devi , Megasari Ni Luh Ayu , Lusida Maria Inge , Juniastut Juniastut , Soetjipto Soetjipto
Published: December 2024

Context: Rotavirus is the main cause of acute diarrhea among children under five years old. Meanwhile, NSP4 has a role in the development of secretory diarrhea. The NSP4 genotype is divided into 21 genogroups (E1-E21). Information related to rotavirus infection and the role of NSP4 pathogenesis in humans has not yet been described clearly, along with the limited information on the association between NSP4 and VP4.

Aims: To determine the genotype and mutation of NSP4 and analyze the mutation of NSP4 with VP4 genotype and diarrhea severity.

Methods: A total of 51 rotavirus-positive samples were collected from children with acute diarrhea between August-December 2016 and June-August 2018 from two hospitals and two primary healthcare centers in Bandar Lampung, Indonesia. The severity of diarrhea data was collected by observation, interviews with the parents or guardians, and medical records based on Ruuska and Vesikari's scores. Identification of the VP4 gene was completed using primers from the WHO Manual of RV Detection and Characterization Methods protocols. P types of these samples were then determined by sequencing methods. DNA amplification for NSP4 gene was carried out using the primers described previously. Lastly, the amplified viral genes were subjected to sequence analysis.

Results: In this study, amino acids substitution was found in H1, H2, H3 domain, enterotoxin region, VP4-binding site, and VP6-binding site from E1 and E2 genotype. Unusual combination occurred between P[8] genotype and E2 with amino acid substitution at position 72 in children with severe diarrhea. The enterotoxin region mutation at position 129 and hydrophobic domain H1 at position 14 mostly existed in the NSP4 sequence associated with P[4] and in children with severe diarrhea.

Conclusion: This finding indicated that amino acid variation in the NSP4 sequence related to VP4 genotype but had no association with diarrhea severity.
The antidiabetic effects of konjac glucomannan on the clinical outcomes of patients with T2DM: A systematic review
Authors: Febrinasari Ratih Puspita , Rizqia Puan Nur , Hikmayani Nur Hafidha
Published: December 2024

Context: Type-2 diabetes mellitus (T2DM) is a complex metabolic disorder that causes insulin resistance in the body. On the other hand, konjac glucomannan (KGM) is known to have beneficial effects on diabetes by reducing HbA1c, postprandial glucose, and insulin resistance. However, only a few studies have been conducted in individuals with T2DM or glucose intolerance.

Aims: To evaluate the effectiveness of konjac glucomannan on the clinical outcomes of T2DM patients treated with oral antidiabetic drugs (OAD) and/or insulin.

Methods: A systematic study was carried out based on the PRISMA protocol by synthesizing trials in T2DM patients treated with OAD and/or insulin. Articles were searched from Science Direct, PubMed, Cochrane Library, and ProQuest databases. The primary outcomes studied were glycated hemoglobin (HbA1c), postprandial glucose (PPG), homeostatic model assessment (HOMA-IR), and fasting serum insulin (FSI). Articles meeting the eligibility criteria were assessed for risk of bias using the Jadad's scale.

Results: A total of 129 participants were included from six trials meeting the eligibility criteria, with ages ranging from 25-75 years and duration of KGM intervention lasting from 2-12 weeks. Two studies had a low risk of bias based on Jadad’s score analysis. Significant reductions in HbA1c, PPG, and fasting blood glucose (FBG) were reported in four studies, while HOMA-IR reduction was found in one study. The different types of KGM and duration of administration might have different influences on the effectiveness of glucomannan in the studied outcomes.

Conclusion: Konjac glucomannan can reduce PPG, FBG, HbA1c, and HOMA-IR in T2DM patients on OAD and/or insulin.
Dynamic Behaviours of Non-Uniform Rayleigh Beam under Variable-Magnitude Accelerating Masses and Resting on Non-Uniform Bi-parametric Foundation with General Boundary Conditions
Authors: T. A. Ogunlusi , T. O. Awodola , J. O. Ikare , Okafor N. P.
Published: December 2024

This paper investigates the dynamic behaviours of non-uniform Rayleigh beam under variable-magnitude accelerating masses and resting on non-uniform bi-parametric foundation with general boundary conditions. The problem is governed by a fourth-order partia l differential equation, generalised Galerkin’s method use to reduces the fourth-order partial differential equation to sequence second-order ordinary differential equations. Two cases are examined: moving force (neglecting inertia term) and moving mass (considering inertia). In order to solve the moving force problem, the transverse displacement response is obtained by variation of parameters. In order to solve the moving mass problem, the Runge-Kutta of fourth order is used to obtain the approximate solution because the commonly used Struble asymptotic method was unable to simplify the coupled second order ordinary differential equation due to the variability of the load magnitude. Analytical and numerical solutions (Runge-Kutta) are compared for validation of accuracy of the Runge-kutta scheme and found compared favourably. The results are presented in plotted curves, illustrating the effects of shear modulus, rotatory inertia correction factor results show increased shear moduli and rotatory inertia decrease response amplitudes, and critical speed for moving mass is lower than for moving force, leading to earlier resonance. Resonance conditions for the dynamical system are also established.
Nutrient Release Pattern and Soil Enzyme Activities of Calcareous Soil as Influenced by Phosphate Rich Organic Manure
Authors: Bhosale S. V. , Gosavi A. B. , Ghorpade V. N. , Waghdhare D. S. , Bhosale P. C.
Published: December 2024

A study was conducted at Post Graduate Laboratory, Division of Soil Science, College of Agriculture, Pune to study the nutrient release pattern and soil enzyme activities of calcareous soil as influenced by various levels of phosphorus using organic and inorganic sources. The experiment was conducted in randomized block design with seven treatments replicated three times. The treatments comprised as T1- Absolute control, T2 - RDF (50:75:45 N: P2O5:K2O kg ha-1) through DAP, T3 - RDF (50:75:45 N: P2O5: K2O kg ha-1) through SSP, T4- 25 % P2O5 through PROM, T5- 50% P2O5 through PROM, T6 -75% P2O5 through PROM and T7 -100% P2O5 through PROM and RDF of soybean was used for incubation. The study demonstrated that applying 100% P2O5through Phosphate Rich Organic Manure (PROM) significantly improved soil poperties, by reducing soil pH and calcium carbonate, increasing organic carbon, and enhancing the availability of macronutrients (nitrogen, phosphorus, potassium) and micronutrients (iron, manganese, zinc, copper). Enzyme activities, including urease, dehydrogenase and alkaline phosphatase were improved in calcareous soils, correlating positively with nutrient availability, particularly with phosphorus and micronutrients such as iron and manganese. PROM application was more effective than chemical fertilizers in promoting nutrient mobilization and improving soil enzyme activity over a 120-day incubation period. Strong correlations were observed between enzyme activity and micronutrient availability, especially in treatments receiving 100% P2O5through PROM, indicating its potential to enhance both nutrient cycling and soil fertility.
Effect of Different Doses of Nitrogen Phosphorus and Potassium on Growth and Yield of Rice Cultivars
Authors: Multafu Kyari Emmanuel , Abdulhameed Ahmad , A.G. Ezra, , A. J Nayaya,
Published: December 2024

The experiment was conducted at the screen house of the Department of Biological Science Abubakar Tafawa Balewa University Yelwa Campus Bauchi State, Nigeria, located at 10ͦ 16’ 52’’ N 9ͦ 19’’ longitude and latitude. The objective of this research is to determine rice genotypes nutrient use efficiency under low NPK fertilizer treatments. The whole experiment was randomized using Microsoft excel in a completely randomized block design (CRBD) with four replications, the germinated seedlings of each cultivar from the petri-dish were planted into two each in plastic pots measuring 30cm with drainage holes at the bottom and the soil of 1.5kg was filled into the pot. For the NPK treatments, two levels of fertilizer adopted were 200kg/ha-1 NPK, which was considered as full dose (FD), and the control, while the 100kg/ha-1 NPK was considered as half dose (HD), and the other experiment tag CF, and without application of fertilizer. The whole experiment was given continuous water flooding throughout period. The experimental data collected of plant height, tillers, shoot mass, root mass, and grain yield on FARO 37, FARO 38, FARO 41, FARO 45, FARO 48, FARO 51, FARO 52, FARO 60, FARO 61, FARO 62, FARO 64, FARO 65, and FARO 66 were subjected to analysis of variance, from the results obtained, and the outcome showed was no significant difference between the treatments. This could suggest the rice cultivars resilience to NPK.
Arthropod Richness and Abundance in Brinjal Crop Ecosystems
Authors: Thodusu Mamatha , Hath Tapan Kumar , Kasi Indra Kumar , Pal Suprakash , Mandal Prithusayak
Published: December 2024

In the study on arthropod biodiversity in brinjal with the variety Navakiran, 12 numbers of different insect pests under 6 orders and 12 families were recorded. These included Phyllotreta sp., epilachna beetle, Henosepilachna vigintioctopunctata Fab. cotton aphid, Aphis gossypii Glover, cotton whitefly, Bemisia tabaci (Genn.), cotton jassid, Amrasca biguttula biguttula Ishida, hooded hopper, Oxyrachis terandus Fab., thrips, Thrips tabaci (Linderman), brinjal shoot and fruit borer, Leucinodes orbonalis Guen, short horned grasshopper, Hieroglyphus banian Fab., long horned grass hopper (unidentified), red pumpkin beetle, Aulachophora foviecollis (Lucas) and dipteran fruit fly (unidentified). Besides, six different natural enemies namely, one species of lynx spider (unidentified), one species of Syrphid fly (unidentified), one species of ant (Solenopsis sp.) and three species of ladybird beetles (Cheilomenes sexmaculatus Fab., Coccinella transvarsalis Fab. and Brumoides sp.) were recorded from the field. The cotton aphid showed its peak during 8th SW (Standard Week) while in case of jassid, whitefly and leaf hopper it was during 9th SW. Epilachna beetle had two peaks- during 8th and 18th SW. Brinjal shoot and fruit borer attained peak during 8th SW.
Integrating Remote Sensing and Artificial Intelligence: A Review of Technological Innovations in Wild Life Crime Detection
Authors: Aich Shristi , Rajath Plathothathil Rachael , C A Riya Raj , Katare Nandini
Published: December 2024

Wildlife crime remains one of the biggest global challenges worldwide even up to the current decade. This is even worse when it is compounded by what is referred to as the 'dark figure' where cases go unreported or are not detected by law enforcement agencies due to victim reluctance or sheer inability of the police to arrest all offenders. To address this issue, scientists have used remote sensing techniques to detect illegality using satellite and other aerial images such as drone and airplane images. Since the amount of remote sensing data is growing very rapidly, and increasing even more in the future, efficient computational systems and sophisticated preprocessing methods are essential for handling and analyzing these data. Artificial Intelligence(AI) has been instrumental in this area through functions like object recognition, data integration, filtering, and anomaly detection that aid the efficiency and accuracy of remote sensing exercises. Overcoming scaling challenges, enhancing engagement, and navigating privacy hurdles remain vital for the implementation of live AI-based models. This review article will also try to give a measure of the likelihood of technological solutions to prevent wildlife crimes and the overriding issue of the 'dark figure' and the expanding mass of data through a critical analysis of the literature on the respective remote sensing devices and the AI algorithms that may be used to combine them.
Avrupa Yeşil Mutabakatı Hedeflerine Ulaşmada Hane Halkı Davranışlarının Analizi
Authors: Özen Ercan , Dursun Zühre , Aydın Eda
Published: December 2024

Avrupa Yeşil Mutabakatı (AYM) hedeflerine ulaşılabilmesinde, bireylerin davranışları da etkilidir. Bu nedenle Uşakta yaşayan 411 kişi ile yapılan anket çalışması ile bireylerin AYM düzenlemelere uyum düzeylerinin analiz edilmiştir. Çalışmada faktör analizi, yapısal eşitlik modeli ve farklılık testleri kullanılmıştır. Bireylerin AYM bilgi düzeyleri, bireylerin çevreci davranışları ve dış çevresel değerlendirme düzeyleri ana boyutlar olarak belirlenmiştir. Çalışmanın en önemli sonuçları bireylerin AYM hakkındaki bilgi düzeyinde artışın, çevreci davranışlar üzerinde belirleyici etkiye sahip olmasıdır. Bulgular politika yapıcılar için AYM hedeflerine ulaşmada önemli veri sağlamaktadır.
La neurociencia y el aprendizaje significativo en la educación superior: estrategias para potenciar el rendimiento académico
Authors: De La Cruz Medina Santiago
Published: December 2024

La neurociencia le permite al docente comprender el funcionamiento del cerebro y en función de ello, establecer estrategias enfocadas a mejorar el trabajo educativo, por lo tanto, su finalidad es proporcionar herramientas que ayuden a los estudiantes a aprender, así como también ayuda al docente a enseñar. Las emociones representan una gran influencia en la vida de todo ser humano, de la misma manera, forman parte importante del ámbito educativo, y estas pueden afectar de manera significativa rendimiento académico de los estudiantes, por lo que es determinante que tanto docentes como estudiantes cuenten con la capacidad de gestionar las emociones en función de promover un ambiente de aprendizaje óptimo y con ello apoyar su pleno desarrollo formativo, profesional y personal. El objetivo que se persigue en el presente estudio es analizar el impacto de la neurociencia y el aprendizaje significativo dentro de la educación superior. La investigación presenta un enfoque cualitativo, de tipo documental. De los hallazgos en el contexto de la educación universitaria la neurociencia ha permitido la innovación en cuanto a los procesos de enseñanza aprendizaje. Esta ofrece las bases para determinar el funcionamiento del cerebro y cómo este se constituye, por lo que el sistema educativo puede hacer uso de nuevas herramientas que le permitan mejorar las prácticas educativas, promoviendo la concentración y la gestión de las emociones, para lograr la autorregulación del aprendizaje, lo que a su vez conlleva al afianzamiento de un proceso cognitivo de calidad.
Análisis de los centros universitarios de innovación como motores de desarrollo
Authors: De La Cruz Medina Santiago
Published: December 2024

Los centros universitarios de innovación se desarrollaron para estimular la innovación y el desarrollo económico. Estas son instalaciones dentro de las universidades que brindan asistencia a los emprendedores y empresas en las etapas iniciales al proporcionarles los recursos relevantes, mentoría o incluso contactos que necesitan para tener éxito en los negocios. El objetivo que persigue este artículo es evaluar el papel de los centros universitarios de innovación como fuerzas impulsoras de la innovación y el desarrollo, que es su eficiencia en el fomento del desarrollo empresarial. La metodología fue cuantitativa y predominantemente correlacional-descriptiva. La información se recopiló mediante una revisión sistemática de una variedad de bases de datos. A partir de los resultados, era evidente que las incubadoras empresariales universitarias se han convertido en verdaderos núcleos de creatividad y desarrollo que permiten a los emprendedores contar con un entorno propicio para transformar fácilmente en realidad proyectos exitosos de ideas. De la misma manera, ofrecen recursos y fomentan la colaboración y transferencia de conocimientos entre la academia y el mundo empresarial, lo cual es fundamental para impulsar el crecimiento económico y social.
El rol crucial del defensor del cliente en el sistema financiero ecuatoriano
Authors: Rojas Delgado Mabel Geoconda
Published: December 2024

La presente investigación se constata cual es el rol del Defensor del Cliente en el sistema financiero ecuatoriano, con el propósito de analizar su impacto en la protección de los derechos de los consumidores y a su vez, el énfasis en la transparencia en las operaciones financieras. El estudio se realizó por medio de un enfoque descriptivo, lo que permitió analizar las funciones normativas y los desafíos relacionados a esta figura, los objetivos bases de este trabajo incluyen la sistematización de los fundamentos teóricos, la propuesta de estrategias para fortalecer el impacto y el diagnóstico del estado actual del Defensor del Cliente, constatando que, aunque el Defensor del Cliente cumple un una función clave como mediador en conflictos financieros, enfrenta limitaciones debido a la falta de facultades vinculantes y recursos suficientes. La normativa vigente ecuatoriana, como lo es la Ley Orgánica de Defensa del Consumidor establece un marco que garantiza transparencia e igualdad en las relaciones contractuales financieras, sin embargo, se reflejó que los usuarios todavía tienen barreras para acceder a información clara y de esta manera resolver sus conflictos de manera ágil. Como conclusión, se propusieron estrategias para optimizar su desempeño, incluyendo la implementación de programas de capacitación, la reforma de su marco normativo y la integración de herramientas tecnológicas para agilizar su gestión. Estas medidas buscan consolidar un sistema financiero más transparente y equitativo que fomente la confianza de los consumidores.
Marketing turístico y gestión de imagen: variables para la promoción de destinos
Authors: García Serna Erick , Yepes Gonzalez Edwin , Baquero Edward , Godínez Melo Martha Violeta , García Heredia Daniela
Published: December 2024

Se aborda la importancia de la imagen de un destino turístico en la decisión de compra y la fidelización del turista. Basados en teorías clásicas del marketing, se explora cómo la imagen percibida, compuesta por factores cognitivos y afectivos, influye en la percepción de los turistas antes de su visita. Enfatizando la necesidad de alinear esta imagen con la proyectada, es decir, la que los gestores del destino desean comunicar. Una adecuada gestión de ambas imágenes, junto con las experiencias vividas en el destino, es esencial para generar comportamientos de fidelización, como la intención de regresar y recomendar el destino a otros. Variables como la percepción de seguridad, infraestructura, el entorno natural y la calidad del servicio son clave para construir una imagen positiva. El trabajo sugiere estrategias de marketing, como campañas en redes sociales y la personalización de experiencias, para fortalecer la imagen del destino. Se concluye que una gestión efectiva de la imagen no solo atrae turistas, sino que fomenta su lealtad y comportamientos positivos hacia el destino. Las recomendaciones incluyen el análisis constante de la percepción del turista y la evaluación continua de las estrategias de marketing, garantizando así el éxito del destino en un entorno competitivo.
Análisis de la sustentabilidad empresarial de las MiPymes ferreteras del cantón La Libertad, Modelo Penta-dimensional año 2024
Authors: Perugachi Cruz Néstor Josué , Reyes Tomalá Lorena Gisella
Published: December 2024

La investigación analizó la sustentabilidad empresarial de las MiPymes ferreteras del cantón La Libertad utilizando el Modelo Penta-dimensional, que incluye las dimensiones de gestión global, competitividad, relaciones, impactos y transparencia. Con un enfoque mixto, se combinaron métodos cuantitativos y cualitativos. El censo se compuso de 30 preguntas que permitieron obtener datos de 67 ferreterías verificadas mediante el RUC activo en el catastro del GAD Municipal, mientras que el análisis teórico y la observación directa ofrecieron perspectivas complementarias. El análisis mostró que las ferreterías poseen fortalezas en gestión global y competitividad, reflejando su capacidad de planificación estratégica y adaptación al mercado. Sin embargo, las dimensiones de relaciones y transparencia revelaron inconsistencias y debilidades, especialmente en la comunicación interna, la rendición de cuentas y la colaboración con los grupos de interés. La dimensión de impactos, aunque con avances moderados, destacó como una oportunidad significativa para mejorar la sustentabilidad social y ambiental. Se concluyó que la sustentabilidad empresarial de estas MiPymes depende del equilibrio entre las cinco dimensiones. La gestión global y la competitividad son fundamentales para la estabilidad, mientras que las relaciones y la transparencia tienen un impacto crucial en la percepción externa y confianza de los stakeholders. El uso del Statistical Package for the Social Sciences (SPSS) permitió identificar patrones y tendencias, estableciendo que una gestión más equilibrada puede fortalecer la sustentabilidad del sector ferretero. Este estudio ofrece un diagnóstico útil para mejorar las prácticas empresariales y promover la permanencia de estas empresas en el mercado.
Enhancing educational outcomes through community collaboration: the impact of the education stoplight in Paraguay
Authors: Stumpfs Fernando , Peroni Victoria , Claire Burt Marie , Burt Martín , Parwani Karuna
Published: December 2024

Education in Paraguay remains marginalized, ranking among the lowest in international indices of access and quality. Challenges such as low academic performance, limited parental involvement, inadequate technology, and insufficient infrastructure hinder progress. Experts recommend strategies that promote cooperation between the different actors in the educational community to address these challenges. Responding to this, Fundación Paraguaya introduced the Education Stoplight in 2020, which encourages the participation of the school community in the educational process, with an emphasis on community collaboration. The Education Stoplight is a self-assessment tool that allows students, parents, teachers, and principals to reflect on their role, set personalized goals, and design solutions to contribute to educational success. This mixed-methods study used interviews, focus groups and an analysis of self-assessment responses from 1,694 participants (including students, parents, teachers, and principals) in 30 schools from different regions of Paraguay to answer the questions: What changes do educational actors perceive after implementing the Educational Stoplight, and what challenges persist? Findings reveal that the tool allowed participants to reflect on educational challenges, facilitating the identification of goals and improvements in a personal and collective way. Students noted difficulties in learning practices, parents highlighted gaps in engagement and communication, teachers identified weaknesses in instructional strategies and principals emphasized the need for improved organizational management.
Exclusión financiera y el crédito del sector no regulado como mecanismo de financiamiento en la economía informal hondureña
Authors: Ochoa Nancy
Published: December 2024

En Honduras el sistema financiero es uno de los sectores más importantes para la economía, este contribuye en gran medida al Producto Interno Bruto –PIB-, así lo evidencia el Índice Mensual de Actividad Económica –IMAE- a julio 2024, donde la intermediación financiera, seguros y fondos de pensiones creció en 15.1 % (Banco Central de Honduras 2024). No obstante, los niveles de bancarización aún son relativamente bajos ya que en 2023 solamente el 22 de la población en edad de trabajar tuvo acceso a un crédito% (UNAH-EQUIFAX 2024). En dicha colocación resalta el papel que desempeña el sector financiero no regulado, el cual participa en ese nivel bancarización con un total de 40% de referencias crediticias siendo una de las fuentes de financiamiento que mayormente buscan los hondureños, principalmente los excluidos del sector financiero regulado e inmersos en la economía informal. Se profundiza en las funciones económicas del crédito del sector no regulado, asimismo, analiza las dinámicas implementadas por los diferentes actores que ofrecen dicho crédito, y finalmente evidencia la incidencia que genera en usuarios financieros de la economía informal, principalmente los comerciantes de mercados capitalinos. Dentro de los principales hallazgos se encontró la alta prevalencia y la flexibilidad que ofrecen estos créditos en los mercados informales, especialmente en comunidades con bajo acceso al sistema financiero formal. Sin embargo; las altas tasas de interés son características de estos créditos, esto debido a la falta de regulación y al mayor riesgo percibido por parte de los prestamistas, dichas tasas pueden llevar a ciclos de endeudamiento crónico entre los prestatarios
Navigating Food Allergy Dynamics via a Novel Fractional Mathematical Model for Antacid-Induced Allergies
Authors: Ali Khan Wajahat , Zarin Rahat , Zeb Aurang , Khan Yousaf , Khan Amir
Published: December 2024

This study explores the onset of food allergies in individuals using antacid medications, employing an innovative fractional mathematical model integrating fractional calculus and differential equations. Through this methodology, we analyze the intricate dynamics of food allergy epidemics and their interaction with antacid usage, offering essential perspectives for refining management strategies and implementing early intervention measures. Our research stems from a 2001 case, marking the initial occurrence of a severe anaphylactic reaction to manioc, a novel food allergy. Prompted by the prolonged acknowledgment of incidents involving a tuber ingrained in native Brazilians’ diets for over 500 years, we establish a mathematical framework addressing the persistence of the cassava allergen in the presence of proton pump inhibitors (PPIs). These medications are utilized to reduce gastric acidity in digestive disorders, elevate pH levels, foster the preservation of the allergen and subsequently enhance immune recognition. Our investigation hinges on employing a mathematical model to scrutinize how incidents related to food allergies impact the dynamics of scientific publication. The model, offering a distinctive perspective on food allergy characterization, relies on a novel set of differential equations incorporating fractional Caputo-Fabrizio (CF) operators. Insights into the model’s long-term behavior are derived from a comprehensive examination of its qualitative characteristics and subsequent computational simulations. We establish the existence and uniqueness of solutions within the proposed model, drawing on established results concerning fixed points. Utilizing the Ulam-Hyers method, we determine stability outcomes. For in-depth numerical analysis and simulation, our study employs Newton’s polynomial in conjunction with the three-step Adams-Bashforth numerical technique. The findings underscore the efficacy of fractional order techniques in accurately capturing the complex dynamics of food allergies and providing insightful information crucial for devising effective management plans.
Introducing a New Integral Transform Called “AR-Transform”
Authors: Akbar Muhammad , Nawaz Rashid
Published: December 2024

In this paper, we have propounded a new integral transform called AR-Transform. AR-Transform stand for “Akbar and Rashid Transform”. We discussed functional characteristics of AR-Transform and obtained AR-Transform of some elementary functions. We also proved theorem of AR-Transform for derivatives of a function. We explore its usefulness in physics, engineering and mathematics, by solving different problems, such as, RL series circuit, Uranium decay model, model of simple harmonic motion and other differential equations to illustrate its power and versatility. Our analysis demonstrates that the AR-Transform is a valuable addition to the existing suite of integral transforms and holds great promise for future research and application.
Sistem Informasi Penjualan Hasil Perkebunan Berbasis Web menggunakan Metode Hybrid Waterfall RAD
Authors: Septiano K M. Calvin , Saka Lena Nia , Oktavianti Rossi , Afdhol M. Dwi , Rahayu Sri
Published: December 2024

Sistem informasi berbasis web sangat penting dalam meningkatkan efisiensi dan akurasi penjualan hasil perkebunan yang selama ini dilakukan secara tradisonal. Proses tradisional sering menyebabkan kesalahan data dan menghambat pengambilan keputusan yang efektif. Penelitian ini bertujuan untuk mengembangkan sistem informasi penjualan berbasis web menggunakan metode hybrid Waterfall dan Rapid Application Development (RAD). Penggabungan kedua metode ini dipilih karena memberikan keseimbangan antara pendekatan terstruktur dan fleksibilitas pengembangan. Hasil dari penelitian menunjukkan bahwa sistem ini dapat meningkatkan efisiensi penjualan hasil perkebunan, mempermudah pengelolaan data, dan membantu dalam pengambilan keputusan strategis.
Analisis Strategi Pemasaran Pada Usaha Mikro, Kecil, dan Menengah (UMKM) : Studi Kasus UMKM Kopi Lampung Barat
Authors: Triani Lita , Beryl M. Abid , Naufal M.
Published: December 2024

West Lampung Regency is famous for its natural wealth, with many of its residents working as farmers and many also working as domestic entrepreneurs or often known as MSMEs. West Lampung is known as one of the areas producing high-quality robusta coffee in Indonesia. However, many Micro, Small, and Medium Enterprises (MSMEs) face challenges in marketing their products amidst fierce competition. This study aims to identify internal factors (strengths and weaknesses) and external factors (opportunities and threats), formulate alternative marketing strategies, and create alternative marketing strategies for Coffee in Pekon Kubu Liku Jaya. An effective marketing strategy for coffee MSMEs in West Lampung must include a digital approach, innovative product development, community-based marketing, competitive pricing, and in-depth market analysis. By implementing this strategy, coffee MSMEs can increase their competitiveness and product sales in an increasingly competitive market.
Évaluation des connaissances, attitudes et de la prise en charge médicamenteuse de la dysménorrhée primaire chez les étudiantes de la faculté de pharmacie de Bamako
Authors: MAIGA Hamma Boubacar , CISSE Bakary Moussa , MARIKO Aïchata Ben Adam , Tedongmo Diffo Hermine Laure
Published: December 2024

Résumé: 
Objectif. Évaluer les connaissances, les attitudes et les différents moyens de prise en charge médicamenteuse de la dysménorrhée primaire chez les étudiantes de la Faculté de Pharmacie de Bamako.
Matériel et méthodes.  Nous avons réalisé une étude transversale à visée descriptive avec un recueil prospectif des données allant du 1er mai 2022 au 31 juin 2023. Nous avons réalisé une enquête auprès de 100 étudiantes qui ont accepté de se prêter à notre questionnaire et nous avons recueillis des données socio-démographiques, cliniques et thérapeutiques ; qui ont été analysées sur le logiciel SPSS 26.0.
Résultats. L’âge moyen des étudiantes était de 21,68 ans, les célibataires étaient les plus représentées avec une fréquence. Parmi les 100 participantes, 90 avaient une dysménorrhée primaire (90%). En ce qui concerne la connaissance des dysménorrhées 53,0% des participantes avaient déclaré connaître la dysménorrhée primaire. On notait que 77,78% de nos participantes n´avaient jamais consulté de médecin pour la dysménorrhée primaire. Sur le plan thérapeutique, la grande majorité de nos participantes obtenait les médicaments par automédication, soit 79,69%. Pour ce qui est de la prise en charge médicamenteuse, l’étude a rapporté comme médicament le plus utilisé : le phloroglucinol faisant parti de la famille des antispasmodiques avec un taux de 53,12% suivi de l'ibuprofène faisant parti de la famille des AINS avec un taux de 20,31%.
Conclusion. La dysménorrhée primaire constitue un réel problème compte tenu de sa répercussion sur la vie scolaire des étudiantes qui constituent les bras valides de demain.
Etat des lieux de la réglementation pour l’obtention de l’Autorisation de Mise sur le Marché au Cameroun en 2024
Authors: Djiabe touko Aristide , Khou-Kouz Nkoulou C.H. , Yaba Dana B. , Minyem Ngombi A.P. , Nogha Stéphanie , Mewouo Ndam C.T.R. , Ngobo Ebende B.L , Ndzie Maniben P. , Nko'o Moise H. J , Nnanga Nga
Published: December 2024

L’accès équitable à des médicaments sûrs, efficaces et de qualité est une exigence pour la couverture sanitaire universelle. L'Organisation Mondiale de la Santé (OMS) rapporte que 10,5 % des médicaments sur le marché sont de qualité inférieure et falsifiés. Dans le cadre d’une amélioration continue, notre étude visait d’évaluer l’application de la réglementation pour l’obtention de l’AMM. Il s’agissait d’une étude transversale descriptive avec une approche qualitative qui s’est déroulée à la Direction de la Pharmacie, du Médicament et des Laboratoires du 05 au 29 Mars 2024. Elle a été réalisée via un entretien individuel semi structuré avec les personnels clés du service d’homologation à l’aide de l’Outil d’Evaluation Global (OEG), version 2020 de l’OMS modifié pour l’étude de la fonction réglementaire d’enregistrement et d’AMM avec une performance variant du niveau de maturité de 1 à 4 adoptées à partir d’ISO 9004. L’évaluation a montré que la DPML dispose d'un sys-tème d’homologation fonctionnel des produits médicaux. La mise en œuvre des 6 indicateurs de l’OEG OMS modifié à sa-voir dispositions législatives et réglementaires, organisation et bonne gouvernance, ressources humaines, processus régle-mentaires, transparence, responsabilisation et communication, et le Suivi de mise en œuvre et évaluation des résultats et impacts étaient respectivement de 88%, 63%, 31%, 55%, 25% et 0%. La fonction réglementaire d’enregistrement et d’AMM était implémentée à 59% avec un niveau de maturité de 1. Notre étude a abouti à la performance la plus basse, donc la capacité de la DPML devrait être renforcée pour garantir a disponibilité des produits médicaux sûrs, efficaces et de qualité au Cameroun.
Real-time Monitoring of Peripheral Blood After Electrochemical Therapy by Electrical Impedance Spectroscopy: A Clinical Trial Study
Authors: Aghaei Faeze , Delshad Belal , Mahdavi Reihane , Fardoost Ali , Hajighasemi Farzane , Ataee Hosein , Yousefpour Narges , Abasvandi Fereshte , Miripour Zohreh Sadat , Abdolahad Mohammad , Akbari Mohammad Esmaeil
Published: December 2024

Background: Electrochemical therapy (EChT) is a well-known tumor destruction method, but entering byproducts into the peripheral blood can be a concern. In recent decades, the electrical impedance spectroscopy (EIS) technique has been noticed to help significantly analyze biological materials in real time. Objectives: This study aimed to investigate the role of the EIS technique for the first time in real-time monitoring of peripheral blood after EChT. Methods: This clinical trial study was conducted on 19 women with breast cancer who were routinely treated with EChT between 2022 and 2023 at Shohadaye Tajrish Hospital, Tehran, Iran. Accurate real-time monitoring of dielectric properties of peripheral blood, including Hematologic Factors, blood ions, apoptosis of peripheral blood mononuclear cells, and the balance of peripheral blood properties before and after EChT was measured using EIS in the frequency range of 1 Hz to 500 kHz. Results: peripheral blood impedimetric parameters before and after EChT, based on EIS findings, were similar at all measured frequencies. EIS analysis did not show a significant difference in the mean level of potassium, sodium and calcium ions in the peripheral blood before and after EChT. Also, there was no significant difference in the level of red blood cells (RBC), platelets, and hemoglobin (HGB) before and after EChT. Although the level of white blood cells (WBC) after EChT decreased by about 15%, this difference was not statistically significant. In addition, peripheral blood smear showed no changes in the appearance of peripheral blood cells, and peripheral blood properties were maintained in balance after EChT. Conclusions: EIS can be used as a real-time method to monitor the patient's peripheral blood status without disturbing hematological factors and peripheral blood balance during EChT in breast cancer patients.
Sidgwick’s Dualism of Practical Reason and the Possibility of Divine Sanctions
Authors: Staihar Jim ,   Philosophy Documentation Center
Published: December 2024

In the concluding chapter of The Methods of Ethics, Henry Sidgwick proposes a religious solution to a “fundamental contradiction” of practical reason. In this paper, I raise an objection to Sidgwick’s religious solution to his assumed dualism of practical reason. Then I describe ways of amending his solution in order to avoid the objection. The amendments have shortcomings. I conclude that Sidgwick’s dualism is in need of a non-religious solution.
Workload Monitoring of Throwing Sport Athletes
Authors: Havinga Janel , Green Andrew , Swanepoel Clinton
Published: December 2024

Background: Throwing events involve the full use of the kinetic chain. Therefore, monitoring training loads is crucial to optimizing athlete adaptation while minimizing the risk of fatigue and long-term injury.Aims: This study aimed to determine external load using work calculations and compare them to current session internal workload metrics such as heart rate and rate of perceived exertion. Furthermore, it aimed to monitor workload over a nine-week period.Methods: Internal training load was evaluated using modes of heart rate monitoring and rate of perceived exertion. External training load was calculated as the product of throw distances and implement weight. Acute to chronic workload ratio was calculated by dividing the acute workload by the chronic workloadResults: Twenty-five throwing athletes (age: 19 (3); height: 1.82 (0) meter; mass: 93 (19) kilogram) completed 11 (7) throws in a single field session during which throwing work was calculated (Throw distance: 40.87 (17.54) meter; session-rating of perceived exertion: 198 (269) arbitrary units; Total work: 8719.37 (13960.6) Joule; Average work: 726.61 (1877.92) Joule). Correlations (p0.05) were found between session rating of perceived exertion and average work (r=0.433), session duration and total (r=0.433), and average workload (r=0.523). Negative correlations existed between average heart rate and total work (r=-0.435), average work (r=-0.442), and duration. (r=-0.483). Workloads and acute to chronic workload ratio differed over the 9 weeks (p=0.025).Conclusion: Relationships were reported between calculated average work, s-RPE, session duration, and average heart rate, indicating that monitoring the duration of training sessions will be of value while changing the implement weight in the sessions.
Implementasi Regresi Linear Berganda Prediksi Faktor-faktor Indeks Pembangunan Manusia di Provinsi Jawa
Authors: Riza Noviana , Maresti Fatia Amalia , Azzahra Siti Salwa , Ningsih Salsa Paringga Pangestu
Published: December 2024

The Human Development Index (HDI) is a key indicator for measuring the welfare and prosperity of a region, including West Java Province. This study aims to analyze the factors influencing HDI and predict its future trends. The analysis was conducted using a multiple linear regression method implemented with the Python programming language, with independent variables including Life Expectancy, Expected Years of Schooling, Mean Years of Schooling, and Adjusted Per Capita Expenditure. The results show that Expected Years of Schooling (X3) and Adjusted Per Capita Expenditure (X4) are the most significant factors influencing HDI in West Java, particularly due to the declining trends in these variables. Based on the model, the predicted HDI values for 2024, 2025, and 2026 are 73.19, 72.59, and 71.62, respectively, which fall under the medium HDI category. These findings provide valuable insights for strategic planning to improve HDI in West Java, particularly through interventions targeting the significant variables.
Analisis Perbedaan Goal Orientation Berdasarkan Tingkat Ekonomi Peserta Didik
Authors: Marwan Marwan
Published: December 2024

Goal orientation is one of the developments of learning motivation theory with a belief pattern that leads to different ways of approaching, using and responding to achievement situations. One of the factors that influences goal orientation is economic level. The role of education in several developing countries has highlighted the problem of differences in the level of achievement of learning outcomes between schools, namely differences in the socio-economic status background of students which cause large differences in social levels in schools, thus encouraging the development of schools to achieve maximum learning achievement. This study aims to determine the differences in goal orientation of students who have differences in economic levels. The research method used is qualitative research with a descriptive approach to describe the picture of the differences in goal orientation of students. The results of the study showed that students who are at the middle economic level have a mastery goal type because there is an aspect of social support that supports students in understanding the lesson well. Meanwhile, students who have a performance goal type are at the lower economic level. This is because they get less social support due to their low economic level.
Membangun Resiliensi dengan Konseling Kelompok: A Systematic Literatur Riview (SLR)
Authors: Hartini Ayunda Apriliana , Istiqomah Azizah Nur , Ulayya Devina Lu’lu’ , Islam Diani Izzatul , Makhmudah Ulya
Published: December 2024

Resilience is the ability of individuals to overcome challenges that occur in their lives. Individuals who participated in group counseling tended to experience improved resilience. So that they can develop their resilience when facing a problem. Group counseling also helps students in understanding themselves and the problems they are facing. The method used in this study is the Systematic Literature Review (SLR) method. The SLR method is used to identify, review, evaluate, and interpret all available research with specific relevant topic areas and research questions. The number of articles found was 22 articles with characteristics that were in accordance with the research target. The results showed that resilience with group counseling could increase due to emotional support, instrumental support, information support, and reward support. Resilience building is focused on the core stage of group counseling when conveying the problem, this awareness is the first step in the formation of counseling resilience in group counseling. Increased resilience in group counseling can not only be applied in schools, but can also be applied in the general environment, which distinguishes only the implementation environment and counseling techniques used.
Perspektif Hukum Islam, Hukum Positif dan Mahasiswa Progam Studi PAI UIN Malang tentang Ganti Kelamin
Authors: Hani'ah Wardatul , Hamidah Tutik
Published: December 2024

This study examines perspectives on gender transition from three viewpoints: students of the Islamic Education Program (PAI) at UIN Maulana Malik Ibrahim Malang, Indonesian positive law, and Islamic law. Using a qualitative narrative approach, interviews with ten PAI students revealed that the majority adhere to Islamic teachings, considering gender identity as a divine destiny that should not be altered, except in certain medical conditions. In Indonesian positive law, the process of gender transition is recognized through the court system with medical evidence. Meanwhile, in Islamic law, gender transition is generally rejected, except in cases of intersex. The Fatwa of the Indonesian Ulema Council (MUI) states that gender transition for individuals with a clear gender is haram but permissible in certain medical cases. This study concludes that the issue of gender transition is a complex debate involving religious, social, and legal aspects.
استخدام أسلوب تخمين الكلمة لتنمية استيعاب المفردات لدى طلاب الفصل الثاني بالمدرسة الثانوية الإسلامية الحكومية 11 فيدي
Authors: Abdi Aziz Miswarul
Published: December 2024

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This research aims to determine the students response after applying the word guessing technique in vocabulary teaching at State Islamic senior high school 11 Pidie, and to determine whether using the word guessing technique enhances the ability of second-year students at state Islamic senior high school 11 Pidie. The research method employed by the researcher is an exsperimental approach with a pre-test and post-test design for a single group. The data collection methods used by the researcher include observation questionnaires tests and documentation. The results of the study show that students responses to vocabulary teaching after using the word guessing technique indicate a high level of enthusiasm. the word guessing technique motivates students to learn vocabulary actively, creatively, and enjoyably. Furthermore, the use of the word guessing technique is effective and influential in enhancing students vocabulary comprehension ability at state Islamic senior high school 11 pidie, as evidenced by the t-test result (negative) being smaller than the t-table value (negative), or (-8.703<-1.753).