bluuebunny/crossref_metadata_2025 huggingface dataset:
Transformasi Digital dan Antisipasi Perubahan Ekonomi Global dalam Dunia Perbankan
Authors: Ardianto Risna , Ramdhani Ridwan Faizal , Apriliana Dewi Lisa Octavia , Prabowo Abu , Saputri Yuniar Wandha , Lestari Aris Sri , Hadi Nur
Published: April 2024

Jurnal ini membahas dampak transformasi digital pada sektor perbankan dan upaya antisipasi terhadap perubahan ekonomi global. Transformasi digital telah menjadi fenomena utama yang memengaruhi berbagai aspek kehidupan, termasuk sektor keuangan. Fokus utama penelitian ini adalah menganalisis bagaimana perbankan beradaptasi dengan perubahan global dan mengimplementasikan transformasi digital sebagai strategi utama. Dalam konteks ini, penelitian menggali peran teknologi dan digitalisasi dalam mempercepat layanan perbankan, meningkatkan efisiensi operasional, dan menciptakan pengalaman pelanggan yang lebih baik. Penggunaan teknologi seperti kecerdasan buatan, analisis data, dan teknologi cloud juga menjadi sorotan dalam membentuk landscape perbankan modern. Selain itu, penelitian ini membahas antisipasi perubahan ekonomi global yang dapat mempengaruhi sektor perbankan. Melalui analisis mendalam, penelitian ini mengidentifikasi tantangan dan peluang yang muncul akibat perubahan ekonomi global, seperti fluktuasi suku bunga, ketidakpastian geopolitik, dan tuntutan regulasi yang berkembang. Penelitian ini mengeksplorasi langkah-langkah strategis yang diambil oleh lembaga keuangan untuk mengantisipasi dan merespon dinamika ekonomi global. Fokus khusus diberikan pada upaya meningkatkan ketahanan dan fleksibilitas perbankan dalam menghadapi ketidakpastian ekonomi.
Urgensi Toleransi untuk Mempertahankan Integrasi Bangsa
Authors: Nurfauziah Ayu , Dewi Dinie Anggraeni , Ardiansyah Muhammad Irfan
Published: April 2024

Indonesia merupakan negara yang memiliki berbagai macam perbedaan yang meliputi perbedaan kebudayaan, suku, agama, bahasa, dan adat istiadat yang tersebar di berbagai daerah. Dari banyaknya perbedaan ini tidak hanya menjadi keuntungan tapi juga tantangan bagi Indonesia untuk menciptakan sebuah integrasi agar negara Indonesia menjadi negara yang utuh dan berdaulat. Berbagai konflik bisa muncul dari banyaknya keberagaman yang ada, sehingga membutuhkan banyak penyatuan-penyatuan untuk menciptakan rasa aman dan nyaman dalam setiap perbedaan. Penyatuan-penyatuan ini membutuhkan masyarakat sebagai penggerak persatuan yang bisa dilakukan dengan mengembangkan pemahaman masyarakat tentang pentingnya sikap toleransi dalam lingkungan masyarakat yang memiliki banyak perbedaan. Penulisan artikel ini menggunakan metode kualitatif yang dikombinasikan dengan literature research untuk mendapatkan data yang relevan. Dapat kita sadari, toleransi adalah suatu hal yang sangat penting. Namun sayangnya, sikap toleransi masih belum bisa diterapkan dengan baik dalam kehidupan masyarakat di Indonesia. Sehingga, masih banyak konflik-konflik yang terjadi akibat kurangnya sikap toleransi. Konflik ini dapat menyebabkan perpecahan di masyarakat yang membuat Indonesia belum bisa menjadi wilayah yang utuh dan berdaulat. Perlu disadari bahwa toleransi merupakan hal yang penting dalam kehidupan bermasyarakat.
Keefektifan Model Pembelajaran STAD Terhadap Hasil Belajar Siswa di SMP
Authors: Lestari Risti Tri , Wijayanti Palupi Sri , Herawati Tri Ratna
Published: April 2024

Belakangan ini banyak siswa Sekolah Menengah Pertama terkait hasil belajar di sekolah kurang. Hal tersebut dikarenakan motivasi belajar siswa yang rendah, penggunaan model pembelajaran dalam proses belajar itu penting bagi siswa. penelitian ini bertujuan untuk melihat keefektifan model pembelajaran STAD terkait hasil belajar siswa di Sekolah Menengah Pertama serta usaha meningkatkan hasil belajar siswa. Penelitian yang diambil ialah penelitian kuantitatif yang berupa pre- experimental design dengan jenis One-Group Pretest-Posttest. Subjek penelitian ini ialah siswa kelas VIII SMP N 3 Kasihan 2022/2023. Sebanyak 30 siswa yang menjadi sampel penelitian ini. Menurut Hasil analisis yang diperoleh hasil thitung sebesar 10,127 dan koefisien tersebut signifikan pada 5% dan dk = 28 sehingga didapat t tabel sebesar 2,048 maka thitung > t tabel, serta 30 siswa mengalami peningkatan setelah mengikuti tes (posttest) dengan nilai rata-rata 80,67 yang sebelumnya nilai rata-rata sebesar 78,63 (pretest). Berdasarkan data yang diperoleh, diketahui model pembelajaran STAD dapat meningkatkan hasil belajar siswa sehingga diharapkan dapat diterapkan saat proses kegiatan mengajar berlangsung.
Protecting controlled unclassified information in nonfederal systems
and organizations
Authors: Ross Ron , Pillitteri Victoria
Published: April 2024

The protection of Controlled Unclassified Information (CUI) is of
paramount importance to federal agencies and can directly impact the ability of the
Federal Government to successfully conduct its essential missions and functions.
This publication provides federal agencies with recommended security requirements
for protecting the confidentiality of CUI when the information is resident in
nonfederal systems and organizations. The requirements apply to components of
nonfederal systems that process, store, or transmit CUI or that provide protection
for such components. The security requirements are intended for use by federal
agencies in contractual vehicles or other agreements established between those
agencies and nonfederal organizations. This publication can be used in conjunction
with its companion publication, NIST Special Publication 800-171A, which provides a
comprehensive set of procedures to assess the security requirements.
Educación transfronteriza en la región Tijuana-San Diego: retos ante el COVID-19
Authors:   Universidad Autónoma de Baja California, Mariscal Nava María Guadalupe , Ocegueda Hernández Marco Tulio ,   Universidad Autónoma de Baja California
Published: April 2024

La pandemia del COVID-19 implicó un cambio repentino en las actividades cotidianas de millones de personas, lo que provocó el cierre de ins-tituciones educativas, laborales y de distintas fronteras a lo largo y ancho del mundo. En el caso de la frontera Tijuana-San Diego, su cierre fue una medida preventiva que adoptó de forma unilateral el estado de California, para minimizar la propagación de casos activos del SARS-CoV-2. Esto trajo por consecuencia que se afectara en gran medida la economía de ambas ciudades de esta región transfronteriza, al restringirse los flujos e intercambios comerciales. Además, esta situación también impactó signi-ficativamente en el sector educativo; ya que, los estudiantes que realizaban el cruce transfronterizo de Tijuana a San Diego de manera cotidiana para asistir a la escuela se vieron afectados con las normativas que implicaba el confinamiento.
Los solicitantes de asilo durante el gobierno de Joe Biden: caos en la frontera México-Estados Unidos
Authors:   Universidad Autónoma de Baja California, Mariscal Nava Dulce María , Torre Cantalapiedra Eduardo ,   El Colegio de la Frontera Norte
Published: April 2024

Desde la década de los noventa, los sucesivos gobiernos estadounidenses han tenido como objetivo tomar el control de su frontera suroeste reduciendo los cruces irregulares. Esta dinámica se exacerbó en el gobierno del presidente Donald Trump, pues durante su mandato no solo los migrantes fueron repelidos, sino también los solicitantes de asilo. Con respecto a estos últimos, la administración Trump siempre se ha mostrado recelosa, señalando que se trata de migrantes económicos que fraudulentamente estarían haciendo uso de la vía legal del asilo político en Estados Unidos para acceder al territorio estadounidense.
Introducción a Draw
Authors:   Universidad Autónoma de Zacatecas ", García Villalobos Alejandro Rodolfo ,   Francisco García Salinas"
Published: April 2024

Vásquez, E. R. (2019), lo define como un editor de gráficos vectoriales y herramienta de diagramación, se puede encontrar una similitud con Microsoft Visio y comparable con CorelDraw, permitiendo crear diferentes tipos de gráficos y exportarlos a formatos como jpg, png, pdf, swf, entre otros. (p.11) Cuando se habla de Draw, se refiere a un programa que consiste en realizar dibujos que incluyan gráficos vectoriales, en donde se ofrece diferentes herramientas las cuales ayudan a crear diferentes clases de gráficos, cuando se refiere a gráficos vectoriales no es más que el almacén de una imagen vectorial, es decir, dos puntos y una línea en vez de una serie de píxeles que representan puntos en la pantalla, de esta manera, los gráficos vectoriales son una manera más sencilla de almacenar y escanear o redimensionar una imagen.
Enjeux éthiques de l’IA en santé - Fiche 4
Authors: Martineau Joé T. , Godin Frédérique Romy , Badr Janine , Castonguay Alexandre , Cousineau Martin , Després Philippe , Motulsky Aude , Nikiema Jean Noel , Petitgand Cécile , Régis Catherine
Published: April 2024

La présente fiche propose une revue des différents enjeux éthiques liés au développement et à l’utilisation des technologies d’intelligence artificielle dans le milieu de la santé, en trois parties. D’abord, nous aborderons les enjeux éthiques liés à l’exploitation de données massives nécessaires à l’entrainement des algorithmes de l’IA. Ensuite, nous présenterons les principaux enjeux éthiques liés au développement et à l’utilisation des SIA en santé, en abordant la façon dont ces systèmes impactent nos vies ainsi que l’environnement physique et social dans lequel nous vivons. Nous présenterons finalement les principales initiatives nationales et internationales en matière d’éthique de l’IA et de la gestion des données, fruits et reflets d’une réflexion globale sur ces sujets. Ces initiatives ont notamment proposé des lignes directrices et principes normatifs servant de guides pour le développement de technologies de l’IA éthiques et responsables. Il s'agit de la quatrième fiche d'une série de 4 développée dans le cadre d'un mandat réalisé pour le Ministère de la Santé et des Services sociaux du Québec (MSSS).
Effectiveness of Group Schema Therapy on Life Attitude and Distress Tolerance in Women Attending Counseling Clinics
Authors: Forouzani Safoura , Norbakhsh Amiri Fatemeh , Abbasi Mahdieh , Pilehvar Zavareh Somayeh , Maghsoudi Shirin
Published: April 2024

Objective: The aim of the present study was to determine the effectiveness of schema therapy on life attitude and distress tolerance in women attending counseling clinics. Methods and Materials: The research method was a quasi-experimental design with pre-test and post-test along with a control group. The study population consisted of women attending counseling clinics in Tehran in 2023. The sampling method was convenience sampling, and the sample size was selected to be 30 individuals (15 in the experimental group and 15 in the control group). Data collection was carried out using life attitude and distress tolerance questionnaires. The experimental group underwent eight 90-minute schema therapy sessions, while the control group did not receive any intervention. Both groups completed the life attitude and distress tolerance questionnaires in two phases: pre-test and post-test. Findings: Findings indicated that after schema therapy, with attention to the mean variables of life attitude and distress tolerance, the experimental group showed significant improvement in the post-test compared to the mean of the control group. Conclusion: Therefore, schema therapy has an effect on the life attitude and distress tolerance of women attending counseling clinics.
PHARMACIST ROLE IN CLINICAL RESEARCH
Authors: GORREPATI Dr. NAVEENA
Published: April 2024

The book “PHARMACIST ROLE IN CLINICAL RESEARCH” provides a comprehensive overview of the pivotal role pharmacists play in the dynamic realm of clinical research. Its extensive exploration begins with an introductory chapter that traces the historical evolution of clinical research and underscores the indispensable contribution of pharmacists within this domain. It elucidates the regulatory frameworks, ethical considerations, and the intricate phases of clinical trials, offering a holistic understanding of the drug development process along with the associated challenges and opportunities. Subsequent chapters delve into the multifaceted involvement of pharmacists in preclinical research, emphasizing their roles in drug discovery, pharmacokinetics, toxicology studies, and formulation development. The book meticulously navigates through the nuances of clinical trial design, patient recruitment strategies, and regulatory compliance, highlighting the pharmacist’s indispensable role in ensuring protocol adherence, drug accountability, and adverse event reporting. Moreover, the text elucidates the pharmacist’s pivotal role in pharmacovigilance and drug safety, emphasizing post-marketing surveillance, signal detection, and risk management strategies. It also delves into the complexities of data analysis and interpretation in clinical research, offering insights into statistical methods, data collection techniques, and real-world evidence generation. Furthermore, the book underscores the importance of pharmaceutical care in clinical trials, advocating for a patient-centered approach encompassing medication therapy management, adherence counseling, and symptom management. It explores specialty areas in clinical research, ranging from oncology and infectious diseases to personalized medicine initiatives, highlighting the pharmacist’s expertise in diverse therapeutic areas. The text also sheds light on biostatistics, clinical research methodology, and emerging technologies, emphasizing digital health innovations, artificial intelligence integration, and global considerations in clinical trial conduct. It delineates career opportunities for pharmacists in clinical research, spanning academic, industry, regulatory, and consulting roles, while also outlining future perspectives and challenges in the field. In essence, “PHARMACIST ROLE IN CLINICAL RESEARCH” serves as an invaluable resource for pharmacists, researchers, and healthcare professionals seeking to deepen their understanding of the pharmacist’s integral role in advancing clinical research and improving patient outcomes. Its comprehensive coverage, from foundational principles to emerging trends, makes it an indispensable companion for those navigating the evolving landscape of clinical research and pharmaceutical innovation.
Research on the Innovative Teaching Model of Product Design Major Multidisciplinary Intersection
Authors: Zhang Li , Hu Fei
Published: April 2024

The rapid development of product design promotes the educational innovation of design specialty. By applying the the interdisciplinary theory, on the basis of mastering its theoretical connotation and characteristics, and taking the the current teaching reform trend and innovation goal of product design specialty into consideration, this paper discusses constructing a system with product design specialty as the core and cultivating students' practical design ability with systematic professional knowledge. It tries to overcome the problems of the traditional teaching mode of product design specialty through interdisciplinary and multi-directional methods, which allows the product design teaching system to apply the innovation and better follow the interdisciplinary development trend.
Surgical Approach to Pulmonary Cystic Adenomatoid Malformations: About an Observation
Authors: Karim Meskouri
Published: April 2024

Congenital cystic adenomatoid malformation (MAKC) is a congenital anomaly of lung development, and is defined as an adenomatoid proliferation of terminal respiratory structures, bronchial and distal pulmonary cystic dilatation, communicating with the bronchial tree and lacking cartilaginous rings, representing approximately 25% of congenital lung lesions, and in 80 to 85% of cases, the diagnosis is made before the age of 2 and is rarely discovered in adulthood. We report 01 case of MAKC diagnosed at the age of 06 months. The diagnosis was based on clinical elements (episode of bronchiolitis with serious signs at the age of 5 months) and radiological (TLT and CT). The lesion was located in the lower lobe of the right lung. The patient underwent a surgical resection such as a lower right lobectomy removing the lesion in one piece. The discovery of a MAKC must be recognized by clinicians. The clinical diagnosis, strongly oriented by the radiological approach, is confirmed by the anatomical pathology, the therapeutic sanction is surgical in the majority of cases. Most authors indicate surgery, especially in early childhood in order to avoid complications, mainly recurrent infections and pneumothorax, and to take advantage of the potential for lung growth.
SOLVING FUZZY NONLINEAR PROGRAMMING PROBLEMS WITH EXTERIOR PENALTY FUZZY VALUED FUNCTIONS
Authors:   Department of Mathematics, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur - 603 203, Tamil Nadu, India, Vanaja G.
Published: April 2024

In this article, we explore the exterior penalty fuzzy valued function method for Fuzzy Nonlinear Programming Problems (FNLPP). We present methods of penalty fuzzy valued function for solving constrained optimization problems by converting to unconstrained optimization problems. Triangular fuzzy numbers are used to represent the problem’s decision variables and coefficients. Using a new fuzzy arithmetic and fuzzy ranking method on the parametric form of triangular fuzzy numbers, the optimal solution of the FNLPP is found by applying the exterior penalty fuzzy valued function method without changing to its equivalent crisp form. We present a numerical example of the suggested method and compare the results to those produced by existing methods
SOLUTION OF FUZZY VOLTERRA INTEGRAL EQUATIONS USING COMPOSITE METHOD
Authors:   Department of Mathematics, College of Sciences, University of Diyala, Diyala, Iraq, Khaji Rokan
Published: April 2024

With the rapid development of of fuzzy Integral equations, the problem of finding its solution becomes increasingly important for knowledge propagation and putting researchers wisdom to work. A recent development trend of fuzzy integral equations is modeling many problems in the field of science and technology. If the unknown function in the considered equation has a solution in terms of infinite series expansion, this proposed method becomes more accurate to find the exact solution. According on the parametric form of a fuzzy number, a fuzzy integral equation converts to two systems of integral equations in the crisp case, and then proposed method is achieved to obtain the exact fuzzy solutions of fuzzy Volterra integral equations. To validate the effectiveness of proposed method, some examples of considered equations are solved and the results show that it achieved the best performance.
ANATOMICAL MORPHO INDEX PROFILE OF TILAPIA (Oreochromis niloticus) CULTIVATED IN THE MINA PADI POND SYSTEM
Authors: Widianti Lia , Petrus Hary Tjahja Soedibya , Sri Marnani
Published: April 2024

The morphological-anatomical index profile is a value of changes in morphology (outer shape) and anatomy (internal organs) as a basis for calculating fish growth. Fish Growth in terms of morphology includes length and weight, while in terms of anatomy can be seen from changes in gonad, liver, and visceral weight. The purpose of this study was to determine the value of the morpho-anatomical index of Nila Fish GIFT (Oreochromis niloticus) cultured in the POKDAKAN Mina Mandiri pond. This research was conducted in the Mina Mandiri Fish Cultivation Group (POKDAKAN) pond, Panembangan Village, Banyumas from September 23, 2021 – November 28, 2021. The method used in this study was a survey method where the data was processed and analyzed descriptively and compared with the literature related. The results of the morpho-anatomical index of Nila Fish GIFT included a hepatosomatic index (HI) of 0.31%, a viscerasomatic index (VI) of 14.09% and a gonadosomatic index (GI) of 2.61%. The fish condition factor value was 1.05557 and the length-weight relationship was 2.6, which is negative allometric
أساليب ووسائل العلَّامة الحليّ في تحقيق التفاعل الفكري وأثره في استمرار التواصل العلمي دراسة تاريخية تحليلية، المدرسة السيارة أنموذجًا
Authors: Prof. Dr. Hanaa Kazem Khalifa
Published: April 2024

العلَّامة الحليّ الحسن بن يوسف بن المطهر(ت 726هـ)، حرص على تربية وإعداد جيل من الفقهاء والعلماء مع حرص السلطان خدابندة على مصاحبته، من هنا انبثق مشروع المدرسة السيارة التي كانت من الخيام الكرباسية وهي تصحب السلطان في ترحاله وحيث إستقراره، وقد وفر السلطان ما يحتاجه العلامة لمدرسته هذه. وقد راعى العلَّامة الحليّ توفير ما تحتاجه المدرسة من علماء كأساتذة مع ما يحتاجه طلبتها من مستلزمات، وما آلت إليه من تطور حين بنيت لها أبنية مستقرة في وقت من الأوقات.سلط البحث الضوء على مسألة أن هذه المدرسة التي كان عميدها العلامة قد أدارها بجهد ونجاح ملموس، في الوقت نفسه كان عطاؤه مستمرًّا ولم ينقطع كونه عالمًا وأُستاذًا ، فقد ألف الكتب ودرس الطلبة ومنح الاجازات العلمية ،مع الاشارة إلى تنوع العلوم التي درست فيها وإن كانت العلوم الدينية لها الحيز الأكبر.
المنحىَ الفلسفيُّ عند العَلَّامَة الحلّيّ
Authors: Dr. Saleh Mahdi Saleh
Published: April 2024

تنوعت الحقول المعرفية التي درسها وألَّفَ فيها العَلَّامَة الحلي، فدرس الفقه وأصول وعلم الكلام والمسائل الفلسفية التي فرضت حضورها في ذهنه، وبناءً على ذلك نجده يتحدث بعدة أَلسُنٍ ويفكر بعقلٍ واحدٍ متوقف على مسافة واحدة من جميع مسائل الميتافزيقيا والعقائدية كالجوهر الفرد وخلق العالم، وهي من دون ريب موضوعاتٌ شكَّلت المقدمات التمهيدية لإثبات الوجود الإلهي.
Artificial Intelligence - Curse or Blessing? Historical Analysis of Digital Developments up to the First European Law on Artificial Intelligence (AI-Act)
Authors:   University of Economics in Bratislava, Slovak Republic, Krenn Julia
Published: April 2024

Changes in the way people live and work, driven by digitalization and automation, have always triggered fears. Developments in the field of digitalization and automation, as well as the use of artificial intelligence, which has been the subject of much discussion recently, require people in all areas to have a certain degree of adaptability. Increasing complexity, the loss of jobs and the challenges of data protection are just a few examples of the challenges facing not only society but also legislators. The simplification of daily life and the increasing efficiency gains made possible by AI are some of the arguments in favor of using AI. The EU law on artificial intelligence aims to ensure that AI systems brought to market and deployed in the EU are safe and in line with the EU's fundamental rights and values. The groundbreaking proposal is also intended to promote investment and innovation in the field of AI in Europe.
Fragmentation of Public Contracts and Integrity
Authors:   Faculty of Law, University of Craiova, Romania, Voican Mădălina
Published: April 2024

This article explores the impact of dividing government contracts into smaller components, highlighting the risks it poses to transparency and integrity in public procurement. Contract fragmentation can obscure decision-making process regarding public expenditure, reduce healthy competition, and facilitate corruption. Real-world examples illustrate these issues. The analysis highlights the need for strengthening public procurement regulations, increasing transparency, and promoting ethical conduct to mitigate these risks. By understanding the complex relationship between contract fragmentation and integrity, decision-makers and stakeholders can better protect public resources by promoting a fairer and more transparent business environment and upholding ethical standards in public procurement.
An analysis of the Lake Surface Water Temperature evolution of the world’s largest lakes during the years 2003-2020 using MODIS data
Authors:   Global Change Unit. Image Processing Laboratory, University of Valencia. Spain, Sobrino José A. , García-Monteiro Susana ,   Global Change Unit. Image Processing Laboratory, University of Valencia. Spain, Julien Yves ,   Global Change Unit. Image Processing Laboratory, University of Valencia. Spain
Published: April 2024

The Lake Surface Water Temperature (LSWT) evolution is analysed in ten of the largest lakes in the world: Caspian Sea, Superior, Victoria, Huron, Michigan, Tanganyika, Baikal, Great Slave Lake, Erie and Ontario. The time span selected is 2003-2020 and the satellite product, MODIS Level 3 SST Thermal IR 8 Day 4km V2019.0. Results show warming trends ranging from 0.012⁰C/yr. in the Victoria Lake to 0.083 ⁰C/yr in the Baikal Lake. Results have been validated with the product MOD11L2 LSWT estimations for the years 2003-2014 in the Laurentian Great Lakes, obtaining correlations between 0.962 and a 0.998. The validation has been enlarged by considering Sentinel 3 observations from the Issyk-Kul lake, with a 0.99 correlation. The validation shows that the MODIS SST product is capable of estimating the LSWT parameter with a high precision.
Hidden in Plain Sight: reconsidering the value of social reproduction, work and nature
Authors: Tomlin Julie
Published: April 2024

Taking as its starting point Marilyn Waring’s painstaking research into the workings of the United Nations Systems of National Accounts (UNSNA), this paper sets out to engage with critiques of the use of annual growth in Gross Domestic Product (GDP) as a measurement of national wellbeing. Attention then turns to the current COVID-19 pandemic, which is read for indications not only of the failure of neoliberalism’s pursuit of economic growth to secure the wellbeing of citizens through the, but also for signs and ways that narratives and values have been disrupted since March 2020. Two strands of interlinking thought are then set out: the degrowth movement with its arguments for care-focused approaches to political economy, and the search for alternatives to the current ‘growthism’. Feminist criticism of the degrowth movement’s failure to engage with the work of Waring and ecofeminists more generally, as well as the limitations of the term ‘care’ open up further exploration of the devaluation of nature, women and social reproduction work. Val Plumwood’s feminist critique of the master identity and the dualisms that are derived from it, particularly in relation to slavery, are followed through into Silvia Federici’s assertion that the development of capitalism was facilitated by violence and devaluation, of women and of their work. To the search for resources that inspire fresh imaginaries of a world in which difference is not linked to hierarchy and dominance is added the story of “the lowly Jesus” washing his disciples’ feet. Jesus’ disruption of dualisms associated with the household and hospitality, is situated in contrast with the role of the Church in upholding dominant power models. In conclusion, the paper returns to the issue of growth and its destructive impacts on the earth, making clear that progress within the capitalist system is not commensurate with freedom for women or the wellbeing of the earth. The urgent need for solidarity across gender, race and class difference that engages with the earth as a political subject is offered as a basis for the search for alternatives to growth.
The Eucharist as Iconic Experience of Divine Love: Ancient – Future Orienteering with Julian of Norwich
Authors: Lapish Marisa
Published: April 2024

This paper explores Julian of Norwich’s experience of divine love through her understanding of “poynte,” culminating in her mystical revelation of the blood of Jesus. In the medieval context of plague, war, and hopelessness, Julian experiences the blood of Jesus on the cross present in the Eucharist as a place of safety and joy, something which can speak to the contemporary reader during this time of pandemic, racial strife, and global pessimism. First, the stage is set by historically examining the socio-cultural milieu of fourteenth-century England, mystical spirituality, and sacramental practice of the Eucharist in the medieval Church. Next, the image of blood as it relates to Julian Norwich’s idea of time expressed as “poynte” in her Showings is presented to illuminate the transformation of suffering into God’s great love which upends all social and religious barriers to unify people in neighborly love. Contemporary implications are made for viewing the Eucharist as icon of remembrance through which Christ is experienced in his suffering at a kingdom table of divine love for a world that suffers and bleeds. Julian of Norwich presents visions of healing, restoration, and theosis where all of humanity’s wounds are healed by Jesus’ bloody wounds. In a Eucharistic preview of the festal banquet of kingdom shalom, Julian’s vision of divine love as a place of safety and joy inform a present Eucharistic table where all are welcome for Jesus is present with his suffering ones and iconically in the faces of his wounded children gathered around the table.
LET Readiness of Technology and Livelihood Education (TLE) Pre-Service Teachers in DMMMSU NLUC: Basis for a LET Review Material in TLE
Authors: Randulph
Published: April 2024

Pre-service teachers’ success in the LET shows that they have gained enough and comprehensive knowledge on their subjects, which certifies their readiness for the professional world. This study aimed to determine the level of LET readiness of the pre service teachers in DMMMSU-NLUC, as well as identify their strengths and weaknesses. This will become a basis in designing a LET Review Materials. It utilized descriptive – survey research design. Fifteen TLE pre-service teachers of the College of Education was the population of the study. The findings of the study indicate that, Cosmetology and Entrepreneurship were the strengths, while Food Technology, Business Math, Basic Drafting, Electronics Technology, Electrical Technology, Carpentry and Masonry, and Plumbing, subjects were identified weaknesses of the pre-service teachers, these results imply that they lack the necessary readiness in taking the Licensure Examination for Teachers. The College of Education shall implement enhanced LET Intervention Program for the LET takers.
Værdien af de danske naturressourcer
Authors: Gravgård Pedersen Ole , Birch Sørensen Peter
Published: April 2024

Værdien af de danske naturressourcer var, da den toppede i 2002, tæt på 360 mia. kr., men er siden aftaget jævnt til 182 mia. kr. i 2021 (2010-priser, kædede værdier). I perioden 1990-2021 er naturressourcernes samlede værdi faldet med ca. en tredjedel.Udviklingen har generelt været helt domineret af olie- og gasreserverne i Nordsøen. Værdien af disse svandt dog helt ind i årene 2018-21 vurderet ved årets priser. Det næststørste bidrag til naturressourceværdien kommer fra den danske fiskebestand.Fra 1990 til midten af 00’erne faldt værdien heraf fra 24 mia. kr. i faste priser til 16 mia. kr. Det var også niveauet i 2021. Værdien af vedmasse i de danske skove er øget jævnt fra 11 mia. kr. i 1990 til 17 mia. kr. i 2021. Indregning af udtømningen af naturressourcer og ændringer i værdien af de biologiske aktiver i nationalregnskabet fører ikke til et meget ændret billede af den økonomiske udvikling.
Omkostningen ved tab af biodiversitet i den grønne nettonationalindkomst
Authors: Bredahl Jacobsen Jette , Lundhede Thomas
Published: April 2024

Artiklen præsenterer, hvordan omkostningen ved tab af biodiversitet er udregnet i den grønne nettonationalindkomst. På baggrund af den danske rødliste estimeres tilbagegangen af arter hvert år i perioden 1990-2020. Et studie af befolkningens marginale betalingsvilje for beskyttelse af truede arter bruges til at udregne den årlige løbende omkostning ved truslen mod biodiversitet og den årlige reduktion i naturkapital som følge af tab af arter. Den årlige omkostning ved truslen mod biodiversitet udgør godt 65 mia. kroner (2023-niveau), og omkostningen ved tabet af arter udgør knap 60 mia. kroner årligt. Omkostninger ved biodiversitetstab er dermed blandt de højeste træk på Danmarks naturkapital. Fokus i studiet er på ikke-brugsværdier, og de estimerede omkostninger er derfor et underkantsskøn for biodiversitetens samlede værdi.
Det grønne BNP – begrænsninger og muligheder
Authors: Elmeskov Jørgen
Published: April 2024

Beregningen af en tidsserie for det grønne BNP i Danmark er et gennembrud, der på sigt kan give miljøhensyn en mere prominent placering i politikdiskussionen og føre til en mere reflekteret prioritering på området. Det argumenteres, at hovedresultaterne af analysen virker kvalitativt intuitive, men at der i sagens natur er en række muligheder for at overveje og forbedre analysen. Det argumenteres også, at etablering af en passende politisk proces og et institutionelt rammeværk er vigtigt for at give de fremtidige beregningsresultater det ønskede gennemslag på politikdiskussionen.
Rural-Urban Inequalities and Spatial Justice in Europe
Authors: Woods Michael
Published: April 2024

This paper examines patterns of rural-urban inequality in Europe. Econometric analysis of quantitative data, new large-n survey data, and stakeholder interviews are utilised, revealing a broad trajectory of convergence between rural and urban areas that is cross-cut by pockets of persistent disadvantage and by contrasts between different parts of Europe. The paper employs the concept of spatial justice to consider the factors shaping these patterns and their political effects. It shows that while EU programmes have had some impact on material measures of inequality, perceived spatial injustice remains, creating opportunities for disruptive political movements.
The noble cause of medicine – fact or fallacy?
Authors: De Roubaix M
Published: April 2024

The aim of the article is threefold: to argue and motivate that unnecessary surgery is a worldwide phenomenon, that it exposes patients to unwarranted risks and that patients should actively participate in decision-making and take a shared responsibility to protect their interests. There is a firm belief that the enterprise of medicine is something of value – both intrinsically because being healthy is good and instrumentally since being healthy allows us to do what we wish to, to attain happiness and to live valuable lives. However, this can only hold if treatment is justified in terms of accepted evidence-based criteria. Imperative for all forms of treatment, including costly and invasive investigations, this is particularly true for surgical interventions because no surgery is without risk. Surgery performed outside of the norms of accepted indications constitutes a grave form of assault. Medicine is a noble cause if we stick to the rules and help each other to do so. As professionals, our most fundamental regulation is by ourselves.
Significance and perspectives of fisheries improvement
Authors: Mikavica Dragan
Published: April 2024

Fish production in the Republic of Srpska is not at the same level as more developed countries in the world. However, all the necessary preconditions for a more intensive fish production are present. Republika Srpska has a large water potential and if only part of that water potential was used, fish production would increase significantly. Fish farming can be developed on classic temperate or cold water farms, on natural hydrographic localities and in non-classical ways (cage farming, recirculation systems, individual farms, etc.). For the non-classical fish production, reproductive centers are necessary in which sexually mature individuals would spawn and be reared to pre-consumption size (juvenile fish), and then, in the live state, these individuals could be transferred to the farm site. A larger volume of fish production would be of financial significance, but also it would have an impact in the field of employment. Fish produced on farms can be processed further. A fish feed factory is also necessary for the development of fishing. Fish production should be harmonized with the criteria for the quality of fish meat. Although to a lesser extent, the catch of fish from natural aquatic ecosystems contributes to a degree to the development of fisheries in the Republic of Srpska (sport and commercial fishing).
Assembly of multilayer phthalocyanine vanadium oxide molecules on Ag2Sb alloy monolayer
Authors: Li Xiao-Yu , Peng Lan-Qin , Zhao Han , Xing Yun , Deng Yan-Tao , Yu Ying-Hui ,   School of Physics, Hubei University, Wuhan 430062, China
Published: April 2024

Fabricating ordered molecular films and further tuning their assembly behavior is important for constructing organic devices with diverse performances. By using high-resolution scanning tunneling microscopy, in this work, we demonstrate that well-organized vanadyl phthalocyanine (VOPc) films can be formed via ‘bottom-up’ molecular self-assembly on a binary alloy Ag2Sb/Ag(111). The Ag2Sb monolayer is prepared by evaporating Sb atoms on clean Ag(111) and followed by annealing. The VOPc molecules are deposited on the Ag2Sb layer via thermal evaporation. The molecular configuration, structural and orbital characteristics of VOPc are clearly clarified at a submolecular level. It is found that initially the ordered VOPc membrane only exhibits the O-up adsorption configuration. Its square-shaped unit cell consists of five VOPc molecules where two adsorption orientations coexist with the horizontal axis of VOPc which is rotated by about 11° or 21° relative to the side of the unit cell. Due to the molecular dipole-dipole interaction, further-deposited molecules result in the assembly of the second-layer VOPc films with the O-down configuration and the square-shaped unit cell that contains only one VOPc molecule. Subsequently, due to the dipole-dipole interaction between layered molecules, following VOPc molecular layers adopt alternating O-up and O-down configurations as well as the square-shaped unit cell, similar to the case of the second layer. In addition, we find that the molecular orbitals overlap in each assembled molecular layer due to the π-π interaction which could facilitate the charge transport along the π stacking direction of VOPc. This research provides possibility to regulate the adsorption configuration and assembly behavior of functional organic molecules on metal surfaces by forming surface alloys.
LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction
Authors: Peters Colin H , Singh Rohit K , Langley Avery A , Nichols William G , Ferris Hannah R , Jeffrey Danielle A , Proenza Catherine , Bankston John R
Published: April 2024

Lymphoid restricted membrane protein (LRMP) is a specific regulator of the hyperpolarization-activated cyclic nucleotide-sensitive isoform 4 (HCN4) channel. LRMP prevents cAMP-dependent potentiation of HCN4, but the interaction domains, mechanisms of action, and basis for isoform-specificity remain unknown. Here, we identify the domains of LRMP essential for this regulation, show that LRMP acts by disrupting the intramolecular signal transduction between cyclic nucleotide binding and gating, and demonstrate that multiple unique regions in HCN4 are required for LRMP isoform-specificity. Using patch clamp electrophysiology and Förster resonance energy transfer (FRET), we identified the initial 227 residues of LRMP and the N-terminus of HCN4 as necessary for LRMP to associate with HCN4. We found that the HCN4 N-terminus and HCN4-specific residues in the C-linker are necessary for regulation of HCN4 by LRMP. Finally, we demonstrated that LRMP-regulation can be conferred to HCN2 by addition of the HCN4 N-terminus along with mutation of five residues in the S5 region and C-linker to the cognate HCN4 residues. Taken together, these results suggest that LRMP inhibits HCN4 through an isoform-specific interaction involving the N-terminals of both proteins that prevents the transduction of cAMP binding into a change in channel gating, most likely via an HCN4-specific orientation of the N-terminus, C-linker, and S4-S5 linker.
Coordinated molecular and ecological adaptations underlie a highly successful parasitoid
Authors: Pang Lan , Fang Gangqi , Liu Zhiguo , Dong Zhi , Chen Jiani , Feng Ting , Zhang Qichao , Sheng Yifeng , Lu Yueqi , Wang Ying , Zhang Yixiang , Li Guiyun , Chen Xuexin , Zhan Shuai , Huang Jianhua
Published: April 2024

The success of an organism depends on the molecular and ecological adaptations that promote its beneficial fitness. Parasitoids are valuable biocontrol agents for successfully managing agricultural pests, and they have evolved diversified strategies to adapt to both the physiological condition of hosts and the competition of other parasitoids. Here, we deconstructed the parasitic strategies in a highly successful parasitoid, Trichopria drosophilae, which parasitizes a broad range of Drosophila hosts, including the globally invasive species D. suzukii. We found that T. drosophilae had developed specialized venom proteins that arrest host development to obtain more nutrients via secreting tissue inhibitors of metalloproteinases (TIMPs), as well as a unique type of cell—teratocytes—that digest host tissues for feeding by releasing trypsin proteins. In addition to the molecular adaptations that optimize nutritional uptake, this pupal parasitoid has evolved ecologically adaptive strategies including the conditional tolerance of intraspecific competition to enhance parasitic success in older hosts and the obligate avoidance of interspecific competition with larval parasitoids. Our study not only demystifies how parasitoids weaponize themselves to colonize formidable hosts but also provided empirical evidence of the intricate coordination between the molecular and ecological adaptations that drive evolutionary success.
Formin-like 1β phosphorylation at S1086 is necessary for secretory polarized traffic of exosomes at the immune synapse in Jurkat T lymphocytes
Authors: Ruiz-Navarro Javier , Fernández-Hermira Sara , Sanz-Fernández Irene , Barbeito Pablo , Navarro-Zapata Alfonso , Pérez-Martínez Antonio , Garcia-Gonzalo Francesc R , Calvo Víctor , Izquierdo Pastor Manuel
Published: April 2024

We analyzed here how formin-like 1 β (FMNL1β), an actin cytoskeleton-regulatory protein, regulates microtubule-organizing center (MTOC) and multivesicular bodies (MVB) polarization and exosome secretion at an immune synapse (IS) model in a phosphorylation-dependent manner. IS formation was associated with transient recruitment of FMNL1β to the IS, which was independent of protein kinase C δ (PKCδ). Simultaneous RNA interference of all FMNL1 isoforms prevented MTOC/MVB polarization and exosome secretion, which were restored by FMNL1βWT expression. However, expression of the non-phosphorylatable mutant FMNL1βS1086A did not restore neither MTOC/MVB polarization nor exosome secretion to control levels, supporting the crucial role of S1086 phosphorylation in MTOC/MVB polarization and exosome secretion. In contrast, the phosphomimetic mutant, FMNL1βS1086D, restored MTOC/MVB polarization and exosome secretion. Conversely, FMNL1βS1086D mutant did not recover the deficient MTOC/MVB polarization occurring in PKCδ-interfered clones, indicating that S1086 FMNL1β phosphorylation alone is not sufficient for MTOC/MVB polarization and exosome secretion. FMNL1 interference inhibited the depletion of F-actin at the central region of the immune synapse (cIS), which is necessary for MTOC/MVB polarization. FMNL1βWT and FMNL1βS1086D, but not FMNL1βS1086A expression, restored F-actin depletion at the cIS. Thus, actin cytoskeleton reorganization at the IS underlies the effects of all these FMNL1β variants on polarized secretory traffic. FMNL1 was found in the IS made by primary T lymphocytes, both in T cell receptor (TCR) and chimeric antigen receptor (CAR)-evoked synapses. Taken together, these results point out a crucial role of S1086 phosphorylation in FMNL1β activation, leading to cortical actin reorganization and subsequent control of MTOC/MVB polarization and exosome secretion.
Transmigrated Kissing Canines: A Case Report of Bilateral Impacted Mandibular Canines
Authors: Dey Shrabasti , Das Asish Kumar , Burman Subhasish , Maji Abhijit , Khatua Abhishek
Published: April 2024

Mandibular canines, also known as the “cornerstone” of the dental arch, are important factors for dental arch stability, masticatory function, and maintaining natural facial expressions and aesthetics. Due to their eruption pattern and sequence, canines are prone to impactions with a 20 times higher frequency for maxillary canines than mandibular canines. Bilateral impactions of permanent mandibular canines are rare occurrences with a low incidence of 0.12%. Migration of teeth is a frequently documented ectopia. However, pre-eruptive migration across the midline of the arch is an unusual occurrence known as transmigration. Hereby the authors presents a 29-year-old female patient who reported with pain and swelling of the anterior mandible. On examination, it was revealed to be associated with bilaterally impacted permanent mandibular canines associated with transmigration. The case was managed by surgical extraction of both impacted teeth leading to resolution of the pain and swelling.
ЭНЕРГЕТИЧЕСКИЕ БАРЬЕРЫ МИГРАЦИИ ТОЧЕЧНЫХ ДЕФЕКТОВ В TIN ИЗ ПЕРВЫХ ПРИНЦИПОВ
Authors: Горохов С.А. , Резванов А.А. , Резник А.А.
Published: April 2024

Рассмотрена объёмная диффузия по междоузельному механизму и по механизму вакансий примесного атома Cu в гранецентрированном кубическом нитриде титана. Рассчитаны из первых принципов в рамках теории функционала плотности по методу восходящих изображений значения энергетических барьеров миграции атомов меди на обеих подрешётках монокристаллического TiN и по междоузельным положениям, а также энергетические барьеры миграции вакансий в окрестности примесного атома Cu. Проведены оценки корреляционного множителя для диффузии по вакансионному механизму, получены зависимости изменения межатомных расстояний при миграции Cu, а также продемонстрировано изменение плотности электронных состояний при скачке примесного атома Cu на близлежащую вакансию титана.
Buchwertübertragungen nunmehr auch zwischen Schwesterpersonengesellschaften möglich – Auswertung des Beschlusses des BVerfG v. 28.11.2023 und Konsequenzen für die Beratungspraxis
Authors: Krüger Christiane
Published: April 2024

Mit seinem am 12.1.2024 veröffentlichten Beschluss vom 28.11.2023 (Az. 2 BvL 8/13, FR 2024, 171) hat das BVerfG mehr als 10 Jahre nach dem Vorlagebeschluss des I. Senats des BFH § 6 Abs. 5 Satz 3 EStG in der bislang geltenden Fassung für verfassungswidrig erklärt. Hiermit zog es einen Schlussstrich unter einen seit Jahren schwelenden Streit um eine Rechtsfrage, hinsichtlich derer praktischen Handhabung zwischen Finanzverwaltung, Rechtsprechung und Literatur seit Jahren keine Einigkeit bestand und die Auslöser für den als solchen bekannt gewordenen „Zoff im BFH“ war. Das BVerfG erachtet es als unvereinbar mit dem Gleichheitssatz des Art.3 Abs.1 GG, dass eine Buchwertübertragung von Einzelwirtschaftsgütern zwischen Schwesterpersonengesellschaften bislang nicht möglich war. Es hat den Gesetzgeber daher zu einer rückwirkenden Neuregelung verpflichtet. Diese aus Sicht der Beratungspraxis zu begrüßende Entscheidung wird den Gesetzgeber jedoch in Teilen vor nicht unerhebliche Herausforderungen stellen. Lösungsansätze dazu sind im nach Redaktionsschluss ergangenen Referentenentwurf eines JStG 2024 erkennbar geworden. Diese konnten hier nicht mehr berücksichtigt werden.
Models of Cardiovascular Disease: Measurement of Arrhythmogenic/Antiarrhythmic Activity in the Guinea Pig
Authors: Guillaume Philippe , Provost Daniel , Lacroix Pierre
Published: March 2009

The protocols described in this unit are used to assess the effects of new chemical entities on arrhythmias in the guinea pig. In the anesthetized guinea pig, arrhythmias are induced by a slow intravenous infusion of digoxin, which provokes extrasystoles, ventricular tachyarrhythmias, and ultimately cardiac arrest. Imipramine precipitates the occurrence of arrhythmias, whereas propranolol shows protection against them. Curr. Protoc. Pharmacol. 44:5.1.1‐5.1.5. © 2009 by John Wiley & Sons, Inc.