bluuebunny/crossref_metadata_2025 huggingface dataset:
PENERAPAN SIKAP DAN MANTRA SEMBAHYANG DALAM PENGUATAN SPIRITUALITAS PADA SISWA PASRAMAN DHARMAGITA BLIMBING KARANGNONGKO KLATEN
Authors: Dwijati Ni Putu , Waluyo Joko , Murniati Wiwit , Putry Devi Ardika , Dharmastuti Rasmiati , Nindya Trisna Ayu , Santiawan I Nyoman
Published: May 2024

The community service activities carried out at the Dharmagita temple intend to hold a "vidyota pasraman" with the theme "Implementation of religious dharma in Dharmagita pasraman", namely education and short training aimed at Hindu youths packaged in the form of an pasraman with the quantum learning method, which will be filled with learn about daily mantras and how to apply them in daily life. At this Pasraman, participants will also be given training on good and correct prayer attitudes that may not be obtained in formal education at school. Therefore according to the theme that is being carried out, this pasraman can produce quality Hindu youths and can strengthen Sradha and Bhakti Hindu youths so that they can further advance Hinduism in Klaten Regency. This Pasraman teaches early childhood and elementary school children at the Dharmagita Blimbing Pasraman about simple mantras, good and correct prayer attitudes, teaches middle and high school youth about the Kramaning Worship Mantra and good and correct prayer attitudes. With this pasraman, Dharmagita pasraman students can better understand and be able to practice mantras and prayer attitudes well.
Periodistas frente a los monitoreos de medios: un análisis desde la teoría del campo
Authors: Rodelo Frida V. , Casillas Olivares Zariá
Published: May 2024

Los monitoreos de medios no suelen acompañarse de indagaciones sobre la manera en que las y los periodistas consumen e interpretan estos proyectos. Mediante entrevistas, este estudio llena ese vacío de información al centrarse en la subjetividad de periodistas de medios monitoreados. El estudio, fundamentado en la teoría del campo de Bourdieu, reveló posiciones frente al monitoreo agrupadas en dos polos (conservar/subvertir el campo) estructurados en torno a la acumulación de capitales. Conocer las dinámicas internas del campo periodístico permitió comprender su grado de apertura al cambio.
CALM & CARE: A CHILD-CENTRED DIGITAL THERAPY PLATFORM FOR MENTAL HEALTH
Authors: Zannat Nahreen , Mahmud Murni
Published: May 2024

Mental health, as critical as physical well-being, has gained significant importance during the COVID19 pandemic. Moreover, pandemic-induced lockdowns have exacerbated mental health issues, including suicides, spousal violence, and domestic bullying. Consequently, the demand for digital therapeutics has surged, manifesting as mobile and web applications and facilitating remote access to support. However, children have been underserved in this category despite their vulnerability to the emotional consequences of school closures and caregiver distress. This study's objectives and methodology encompassed developing a child centric digital therapy mobile application, conducting usability testing for optimal user-friendliness, creating content compliant with industry standards, gathering user feedback for improvements and providing ongoing maintenance for the application's effectiveness. The resulting 'Calm & Care' prototype empowers parents to authorise counselling sessions and motivational content for their children at home. Ten families participated in user testing, yielding positive feedback praising the vibrant interface, child-friendly visuals, and simplified language for an enhanced user experience. 'Calm & Care' can enable local clinics to accept mental health patients with lower infection risks and increase treatment success. This research underscores the pivotal role of digital solutions in addressing children's mental well-being during the pandemic.
Insiders/Outsiders in America: Students Capture Shifting Perspectives
Authors: Ayers Madelyn , Furlong Shanyn , Wood Chris , Bejaran Solorio Leslie , Cheng Shannon Chloe , Mendez-Lemus Christopher
Published: May 2024

What the U.S. is and ought to be depends on who you ask, where they stand, and their personal story. In this volume’s essays, student authors built on their work in Dominican University of California’s 2024 “Religious Nationalism” course to capture some of the divergent possibilities, including shifts in their own perspectives.
Порівняння впливу простатопротекторів на стан ендотелію судин у щурів з хронічним простатитом
Authors: Приступа Б. В. , Богату С. І. , Бойко І. Ю. , Унгурян Л. М.
Published: May 2024

Порушення гемодинаміки та мікроциркуляції в тканинах передміхурової залози (ПЗ) внаслідок ендотеліальної дисфункції є одним з провідних патогенетичних механізмів розвитку хронічного простатиту. Тому лікувальна ефективність сучасних простатопротекторів значною мірою визначається їхньою здатністю коригувати подібні патологічні зміни в тканинах ПЗ за умов запалення.
Мета дослідження – порівняльне вивчення впливу простатопротектора на основі лікарської рослинної сировини якірців сланких трібестану та комплексу регуляторних пептидів тваринного походження простатилену на стан ендотелію судин у щурів з хронічним простатитом (ХП).
У досдідженні порівнювали вплив поширених простатопротекторів – трібестану та простатилену на стан ендотелію судин на моделі ХП у щурів. Модель ХП у щурів відтворювали одноразовим ректальним уведенням 1,0 мл суміші скипидару з 10 % димексидом у співвідношенні 1 : 4. Простатопротектори (трібестан і простатилен) застосовували одноразово щоденно протягом 30 діб після уведення тваринам флогогену.
Показано, що за умов ХП у щурів розвивається ендотеліальна дисфункція: змінюється вміст S-нітрозотіолів (S-NO) й ендотеліну-1, співвідношення вазодилатаційно-вазоконстрикторного потенціалу, а також спостерігається дисбаланс маркерів ендотеліальної дисфункції – активності еNO-синтази та іNO-синтази.
Дослідження показали, що трібестан в умовно-терапевтичній дозі 60 мг/кг за внутрішньошлунко- вого введення та простатилен у дозі 200 мкл/кг за внутрішньоочеревинного введення протягом 30 діб щурам з моделлю ХП з різною ефективністю стабілізують вміст S-NO й ендотеліну-1 у крові та коригують порушення функції ендотелію судин шляхом зменшення дисбалансу активності еNO-синтази й іNO-синтази. За умов експерименту трібестан характеризувався більш виразним ендотелій протекторним ефектом порівняно з простатиленом.
Retrospective Review and Analysis on Outcome of Cranioplasty: A Series of 38 Cases
Authors: AKM Bazlul Karim  , Riad Habib  , Abu Tahir Mohammad Sahidullah Monsur  , Kawshik Ahmed  , Mir Shamsad Hossain  , Mithun Kumar Dey  , Atique Bin Hussain  , Adnan Moasir Hasnine  , Md Mamun Reza  , Dibakar Chaudhury  , MD Rezwan Radid  , Aziza Khatun  , Md Arif Hasan  , Kazi Shahabulbul Islam  , Md Ashiqul Muhit khan  , Md Ifran Ahmed
Published: May 2024

Background: Cranioplasty (CP) is a straightforward procedure, it may result in a significant number of complications. These include infections, seizures, intracranial hematomas, and others.
Objective: This was a retrospective study on outcome of Cranioplasty.
Materials and Methods: This retrospective study included patients who underwent decompressive craniectomy due to traumatic brain injury with raised ICP, acute subdural hematoma, compound comminuted skull fracture & ICH, between January January 2019 to December 2020 at Enam Medical College & Hospital, Savar, Dhaka. Data were collected in pre-designed data collection sheet and were analyzed using computerbased programme statistical package for social science (SPSS) windows version 25.
Results: This study showed maximum patients (34.2%) were between 21-30 years age. Majority were male (89.5%) and only 5.9% were female. Overall rate of complications was 10.5%. Among them new onset seizure (n = 4), indrawing of skin through bone gap (n=4), hemorrhage (n=2), infection (n = 1), HCP (n = 1), and exposed implant (n=1).
Conclusion: We have found the outcome of cranioplasty was better with titanium mesh plate and screw than conventional fixation of bone with polyglactin, polypropylene suture and titanium miniplate and screw. With polypropylene and polyglactin there is more chance of inward displacement of bone fragment and with miniplate and screw there is still chance of indrawing of bone fragment through the bone gap.  
Bang. J Neurosurgery 2023; 13(1): 20-23
Analysis of Superior Extremity Strength on the Groundstroke Attack Skills of Tennis Athletes
Authors: Saleh M Sahib , Syahruddin  , Saleh Muhammad  Syahrul
Published: May 2024

A tennis player must be able to produce groundstroke attacks effectively because these strokes have an important strategic role in controlling and dominating the course of the match. To produce a groundstroke attack, a tennis player must have muscle strength in the superior extremities, because the superior extremities are the primary source of kinetic energy required to transfer momentum to the racket. Apart from that, good coordination between the muscles of the arms, shoulders, and back is also important to achieve optimality in groundstroke attacks. In a coordinated movement, energy from the tennis player's body is transferred through the arms to the tip of the racket when the racket makes contact with the ball. The aim of this study was to determine how much influence superior extremity strength has on forehand groundstroke skills. The type of research used is a correlational description, involving the independent variable being superior extremity muscle strength while the dependent variable is forehand groundstroke attack skill. The research sample was 20 POMNAS South Sulawesi tennis athletes taken by purposive sampling. The instruments used were the Bouncing Medicine Ball Test and the Hewitt Tennis Performance Test. Analysis through a correlation regression test. The results concluded that the ability to groundstroke attack was influenced by upper limb muscle strength by 59.3%.
Isolation, identification and quantification of flavonoids from the flowers of Staphylea pinnata L.
Authors: Sokolova A. Y. , Poluyanov A. M. , Bardakov A. I. , Sologova S. S. , Bobkova N. V.
Published: May 2024

Introduction. Search for new plant species containing biologically active substances (hereinafter – BAS) is one of the leading tasks of pharmacognosy as a science. The search for flavonoid glycosides in plant raw materials is especially relevant, since they have anti-inflammatory, antioxidant, immunostimulating, as well as weak fungicidal and bacteriostatic action. Staphylea pinnata L. is an endemic plant of the Caucasus, cultivated not only in Georgia, but also in the Russian Federation in the Northern and Northwestern Caucasus. In foreign literature there are studies of antioxidant, antiproliferative and cytotoxic activity of leaf extracts of several species of S. pinnata L., as well as inhibitory activity of COX-1, COX-2 and LTB4 formation. Meanwhile, no serious Russian-language scientific studies on either the chemical composition or pharmacological action of generative organs of S. pinnata were found in the literature. This work is part of a comprehensive phytochemical study of S. pinnata. The aim of the work is to study the qualitative and quantitative composition of flavonoids in the studied object.

Aim. To isolate, identify and quantify flavonoids in flowers and buds of Staphylea pinnata L.

Materials and methods. Alcohol-water extracts from dried generative organs of the studied plant were used as analyzed solutions. Solutions were analyzed on a spectrophotometer SF-2000 (LLC "OKB Spectr", Russia) after sample preparation with aluminum chloride and on an HPLC Nexera-i LC-2040 (Shimadzu Corporation, Japan) equipped with a column and sample thermostat, degasser and autosampler using an individually selected elution gradient of the mobile phase (0.1 % orthophosphoric acid/acetonitrile solution). The primary data were processed using LabSolutions Single LC software (Shimadzu Corporation, Japan). Compounds from the flavonoid group were identified by retention times. Detection was carried out using a UV detector with an absorption wavelength of 365 ± 2 nm.

Result and discussion. Alcohol-water extracts from flowers and buds of S. pinnata L. were obtained. Quantitative evaluation by spectrophotometry for flavonoid content was carried out. A gradient elution mode for HPLC was selected for simultaneous determination of 7 flavonoid glycosides. These chromatographic conditions allowed the identification and quantification of astragaline, cynaroside, cosmosiin, narcissin and rutin in flowers and buds of Staphylea pinnata L. Flavonoid glycosides: raponticin and kaempferol were not detected.

Conclusion. Flavonoid glycosides were isolated from the generative organs of S. pinnata L., a technique for quantitative determination of flavonoid glycosides in alcohol-water extracts was developed, astragalin, cynaroside, cosmosiin, narcissin and rutin were detected and quantified.
Transición de la publicidad impresa a la era digital: un estudio de las estrategias y preferencias de las PYMES en Machala
Authors: Romero-Herrera Angel , Herrera-Pérez Ariana
Published: May 2024

Este estudio examina la adaptación de estrategias de publicidad impresa a la era digital, centrándose en las pymes en Machala, Ecuador. El propósito es comprender las preferencias actuales y estrategias exitosas para navegar en el cambiante panorama publicitario. Basándose en antecedentes, el artículo destaca la necesidad de integrar publicidad impresa y digital. El problema de investigación aborda el desafío de adaptar estrategias tradicionales al entorno digital, con énfasis en cómo las pymes en Machala enfrentan este cambio. La pregunta clave es cómo estas pymes pueden integrar eficazmente ambos medios para mejorar su competitividad. Los objetivos incluyen evaluar preferencias, describir beneficios y proponer estrategias específicas para la transición. La metodología es cuantitativa con encuestas dirigidas a pymes en Machala. Según los datos recopilados, la mayoría de las pymes en Machala aún aprecian la publicidad impresa, particularmente en formatos innovadores y creativos. No obstante, se observa un incremento en la preferencia por canales digitales, como redes sociales y sitios web, señalando una transición progresiva en las prácticas publicitarias hacia el entorno digital. Este resumen enfatiza la convergencia de la publicidad impresa y digital como un paso crucial para el éxito empresarial en el contexto digital actual.
Trayectoria histórica, exponentes y perspectivas del pensamiento sistémico: una revisión integradora
Authors: Salazar-Guamán Ximena
Published: May 2024

Ante la vasta y dispersa producción teórica sobre pensamiento sistémico, este artículo presenta una revisión integradora de su trayectoria histórico-conceptual. Mediante un exhaustivo análisis de literatura especializada, se delinea la transición desde el paradigma mecanicista cartesiano hacia aproximaciones organicistas y holísticas para entender sistemas complejos adaptativos, identificando sus raíces en biología, ecología, cibernética y física cuántica a inicios del siglo XX. Se rescatan los aportes seminales de von Bertalanffy con su Teoría General de Sistemas, Wiener con la cibernética, Ashby con la cibernética moderna y Forrester con la dinámica de sistemas. Asimismo, se examinan derivaciones posteriores hacia la complejidad, destacando contribuciones interdisciplinarias de exponentes europeos como Prigogine, Morin, Luhmann; norteamericanos como Simon, Holland, Kauffman; latinoamericanos como Maturana, Varela, García; asiáticos como Mesarovic, Takahara; y africanos como Juma. El estudio permite sistematizar conexiones entre escuelas teóricas y tendencias contemporáneas bajo un marco unificado. Los hallazgos proporcionan fundamentos históricos y conceptuales útiles para orientar investigaciones futuras sobre pensamiento sistémico y complejo.
Las representaciones sociales sobre la infancia en el Instituto de Menores Lasala y Riglos de Moreno: períodos institucionales desde su inauguración hasta su cierre - prácticas y discursos
Authors: Fernández Andrea , Spinosa Débora , Ponce Rosana
Published: May 2024

Este artículo describe avances de un proceso de investigación que se focaliza en conocer el proceso de configuración de las representaciones sobre las infancias en el Instituto de Menores Mercedes Lasala y Riglos y las instituciones educativas creadas en su entorno, en el período que abarca desde 1944 al año 2000. Se desarrolla a través de un diseño cualitativo, de generación conceptual (Strauss y Corbin, 2001; Rigal Sirvent, 2010). Tiene como objetivos iniciar la reconstrucción, a partir de documentos y testimonios, el proceso de inauguración, desarrollo y cierre del Instituto de Menores Lasala y Riglos y del Instituto de Formación docente que funciona en él; identificar períodos en la historia institucional en función de las diferentes gestiones y establecer vinculaciones entre la historia institucional y las políticas públicas destinadas a la infancia, incorporando voces de actores que fueron parte activa en distintas etapas de su desarrollo. Dada su envergadura, este proyecto se desarrolla en tramos. Específicamente en este artículo nos centraremos en establecer “períodos” o “momentos en el recorrido de las instituciones” y vínculos iniciales respecto a prácticas y discursos que abonen al proceso de configuración de la representación social de las infancias.
FDG PET/CT in Prosthetic Heart Valve Endocarditis
Authors:   , Scholtens Asbjørn Mathias
Published: May 2024

18F-fluorodeoxyglucose positron emission tomography with computed tomographic attenuation correction (FDG PET/CT) is an imaging technique used, among other indications, to demonstrate inflammatory processes including infections. In this doctoral research, we further evaluated the role of FDG PET/CT in demonstrating infections of or around prosthetic valves implanted in the heart (prosthetic heart valve endocarditis). Prosthetic heart valve endocarditis is a disease associated with a high risk of mortality, where a rapid and accurate diagnosis is crucial. Based on the findings of our study, we propose improvements regarding patient preparation prior to imaging, the acquisition of the imaging itself, and the interpretation of the images obtained. The main outcomes were firstly that the use of Heparin as a single administration, coupled with a carbohydrate-restricted diet on the day before FDG PET/CT, results in more interpretable images. Secondly, that the use of standardized processing of the images, applying modern reconstruction techniques, leads to interpretable images on which measurements can be performed that are comparable between different hospitals. Finally, we confirmed these techniques by applying them to a large group of FDG PET/CT studies collected in multiple hospitals in the Netherlands, and demonstrated that both the sensitivity and accuracy of FDG PET/CT for prosthetic valve endocarditis can be increased by their use.
Tongue Hyperpigmentation with Peginterferon α-2b Therapy in Hepatitis B: Case Series With Review of Literature
Authors: Ghosh Saubhik , Samanta Tryambak
Published: May 2024

Peginterferon α-2b (Peg IFNα-2b) continues to be used for treating a selected subset of patients with hepatitis B, in the era of direct-acting antivirals for hepatitis C infection. The authors hereby report four cases of tongue pigmentation among 21 patients with hepatitis B, whom they treated in the last 5 years, where at least 48 weeks of Peg IFN were administered. The lesions were mostly self-limiting, having no temporal relation with response to treatment. To the best of the authors’ knowledge, this is the first case series of Peg IFN-induced lingual hyperpigmentation in patients with hepatitis B, which clinicians should be aware of.
STRATEGI CICIL EMAS DALAM MENINGKATKAN KECERDASAN FINANSIAL MASYARAKAT DAN JUMLAH NASABAH: (STUDI KASUS KCP BANK SYARIAH INDONESIA SITUBONDO BASUKI RAHMAT)
Authors: Widad Romzatul , Marifah Anisa
Published: May 2024

This article aims to describe the BSI KCP Situbondo Basuki Rahmat gold installment strategy and the BSI KCP Situbondo Basuki Rahmat gold installment strategy in increasing people's financial intelligence and the number of customers. The research approach used is qualitative with a field study research type. Data collection applies interviews, observation and documentation. Data analysis uses the Miles and Huberman model. The results of this research are: 1) The BSI KCP Situbondo Basuki Rahmat gold installment strategy was carried out in two stages, planning and implementation. The planning stage is carried out by implementing segmentating, targeting and positioning (STP) strategies. The implementation stage is carried out by implementing the marketing mix; 2) Increasing the number of financial intelligence and number of customers is carried out with three education programs. First, awareness that the value of currency always decreases over time. Second, awareness that the value of property assets always decreases over time. Third, the importance of investing in gold is to save money from a decline in currency value and assets from a decline in value.
Intestinal microbiota and gallstone disease – is there a connection?
Authors: Akhmedov V. A.
Published: May 2024

Cholelithiasis is a fairly common disease of the digestive system, affecting from 10 % to 15 % of the adult population. Despite many studies devoted to this problem, the mechanisms of formation of gallstone disease have not been fully elucidated. Recently, aspects of the influence of the intestinal microbiota on the mechanisms of formation of various pathologies of the gastrointestinal tract such as non-alcoholic fatty liver disease, inflammatory bowel diseases, irritable bowel syndrome, pancreatic diseases, gastroesophageal reflux disease have been considered. The presented review article examines the possible involvement of the gastrointestinal microbiome in the pathogenesis of gallstone disease. The article discusses the role of microorganisms and their metabolites in the formation of gallstones.
Analysis of the clinical diagnostic capabilities of kidney imaging biomarkers based on diffusion-weighted imaging and ASL-perfusion data
Authors: Shkuratova Yu. Yu. , Morozova T. G.
Published: May 2024

Acute kidney failure is a polyetiological disease that is often occurs in patients, which requires a rapid therapeutic response to avoid progression of the condition. Magnetic resonance imaging of the kidneys (MRI) improves the understanding and assessment of pathological processes, supplementing the mandatory diagnostic minimum information in the study of kidney pathology.

Objective. To evaluate the clinical diagnostic capabilities of kidney imaging biomarkers using diffusion-weighted imaging (DWI) and ASL-perfusion data for intensive care unit patients.

Materials and methods. At the first Clinical Hospital in Smolensk 54 patients were examined who were inpatient treatment and in the intensive care unit. All patients underwent ultrasound examination of the kidneys with assessment of blood flow in the main kidney vessels, MRI of the kidneys, with DWI of the kidney parenchyma and ASL-perfusion included in the study protocol. MRI was carried with assessed b-factor 800 and was drawn apparent diffusion coefficient (ADC) maps. When carried ASL perfusion, the field of view covered the area of the parenchyma of both kidneys. The reference method was glomerular filtration rate for all of the patients. The control group was represented by healthy people (n=59). Consent to participate in the study was obtained from patients or their legal representatives. All stages of the study comply with the normative and regulatory documentation of Ministry of Health ща the Russian Federation.

Results. It was concluded that there is a significant difference in ADC for prerenal causes and in ASL for renal causes. In 9 (16.7 %) patients, kidney ADC was 1.5±0.3 mm2/sec, ASL – perfusion – ≤ 250 ml/100g/min, compared with the control group. In this group, negative dynamics were observed within a week, тnegative laboratory dynamics correlates with radiation-based kidney biomarkers (r=0,965).

Conclusion. The criteria of DWI and ASL-perfusion allow us to suspect or confirm the cause of acute kidney failure. A high correlation has been established between radiation biomarkers and laboratory criteria of functional damages (r=0.998), direct correlation between imaging biomarkers and organic kidney disease (r=0,901). These biomarkers make it possible to predict the first stage of acute kidney failure (AUROC 0,995, DI 0,867–0,999).
Perioperative Immune Checkpoint Blockade for Muscle-Invasive and Metastatic Bladder Cancer
Authors: Ramamurthy Chethan , Wheeler Karen M. , Trecarten Shaun , Hassouneh Zaineb , Ji Niannian , Lee Yifen , Svatek Robert S. , Mukherjee Neelam
Published: May 2024

Checkpoint inhibitors offer promise in treating muscle-invasive and metastatic bladder cancer, but the optimal timing of their administration—neoadjuvant or adjuvant—remains unclear. To determine the efficacy of combining checkpoint inhibition with standard cisplatin-based chemotherapy, we conducted a phase II trial of neoadjuvant anti-PD-1 (αPD-1) and anti-CTLA-4 (αCTLA-4), in combination with cisplatin-gemcitabine, for patients with muscle-invasive bladder cancer prior to radical cystectomy. In addition, a novel murine model of spontaneous metastatic bladder cancer was used to compare the efficacy of neoadjuvant versus adjuvant anti-PD-L1 (αPD-L1) treatment. The clinical trial was closed prematurely due to the industry’s withdrawal of drug provision. Adverse events were observed in all patients; however, serious adverse events were not observed in any patient. A complete pathologic response was observed in 50% of the 4 patients enrolled. Response to treatment was significantly associated with elevated urinary T cells including CD8+ and IFNγ+ CD4+ T cells, suggesting potential reinforcement of immune responses by neoadjuvant αPD-1 and αCTLA-4 against bladder tumor cells. These findings suggest that combining chemotherapy and immunotherapy in the neoadjuvant setting could be safe. However, the complete response rate of this four-drug regimen was modest and emphasizes the need for randomized controlled trials to properly assess immunotherapy efficacy in the neoadjuvant setting. In corresponding murine studies, the MB49-met model consistently displayed widespread metastasis, including tumor growth in the lungs, liver, and bowel mesentery, within 20 days of subcutaneous transplantation. Mice receiving surgery plus neoadjuvant αPD-L1 or adjuvant αPD-L1 exhibited improved survival compared to those receiving only αPD-L1. However, no significant difference in survival was observed between the neoadjuvant and adjuvant αPD-L1 cohorts. Furthermore, the timing of neoadjuvant therapy administration (early vs. late) did not significantly impact survival. This study highlights the potential of perioperative immunotherapy in the treatment of locally advanced and metastatic bladder cancer.
Análisis del color en las creaciones de moda desde la expresión artística
Authors: Garre Sánchez Cristina
Published: May 2024

El presente texto nace en el contexto de una investigación sobre la creación audiovisual denominada fashion film. El principal objetivo es poner de manifiesto el uso de tecnologías propias de la creación de imagen estática y en movimiento como medio de expresión artística por parte de artistas que realizan piezas audiovisuales relacionadas con la moda y, en concreto, con el fashion film. Desde la perspectiva del medio audiovisual como forma de expresión artística, se plantea un análisis de las creaciones audiovisuales L’Elélégance (sic) de Sonia Delaunay (1925) y Esencia de una seducción de Eugenio Recuenco (2008), con la intención de alcanzar el objetivo propuesto. Como principales resultados del análisis, se observa que el color es un elemento imprescindible para la creación del relato y expresión para el artista, elevándolo al mismo nivel de protagonismo que el de los propios personajes. Además, se advierte que la tecnología y los medios de los que disponen los artistas intervienen y forman parte de la obra final.
La fotografía taxonómica en el herbario
Authors: Moreno Lucía
Published: May 2024

El artículo aborda la evolución de la estética del herbario, desde los primeros dibujos científicos hasta el surgimiento de la fotografía botánica y su relación con movimientos artísticos como el Art Nouveau. Se destaca el impacto de trabajos como el de Karl Blossfeldt en la fotografía botánica y cómo estas imágenes marcaron un punto de inflexión en la representación de los herbarios.
Se presentan algunos proyectos fotográficos contemporáneos que reinterpretan la estética clásica del herbario y cuestionan la relación entre lo real y lo simulado en la imagen. Estos ejemplos ilustran una relectura crítica y socialmente comprometida, proponiendo un nuevo enfoque en la representación de la naturaleza.
El artículo concluye reflexionando sobre la necesidad de revisar los estándares convencionales de los herbarios, que han relegado a las plantas a meros objetos de estudio, despojándolas de su contexto y significado cultural. Propone una nueva mirada hacia la botánica, tanto desde el arte como desde la ciencia, que reconozca y respete la complejidad y la interdependencia entre las plantas y su entorno, desafiando así la visión patriarcal de la relación entre humanos y naturaleza.
Bienestar cultural, artes escénicas y regeneración urbana: nuevos aspectos que deben ser considerados para la integración social
Authors: Paltrinieri Roberta
Published: May 2024

Este artículo propone una reflexión sobre el impacto y el valor de la cultura en el marco de los procesos de regeneración urbana. Particularmente, se propone reinterpretar la regeneración urbana en clave culturalista. Para ello, y en un plano estrictamente teórico, se discute primero el objeto de la sociología de la cultura, con el fin de demostrar la importancia que tienen las prácticas sociales y la participación cultural en la definición de los imaginarios sociales y en la definición de la vida cotidiana, incluyendo las dimensiones económicas de producción y consumo. Asumiendo el valor social de la cultura, y no solo su valor artístico, y asumiendo asimismo la estrecha relación existentes entre regeneración urbana, cultura y territorio, se desarrolla a continuación el concepto de ecosistemas culturales, que surgen en el seno de las comunidades. A partir de estas premisas teóricas, el texto muestra los resultados de una investigación en la que se estudió la aplicación en Italia del Convenio de Faro. Tales resultados permiten sugerir algunas dimensiones de análisis a partir de las cuales derivar indicadores no económicos que sirvan para evaluar las políticas culturales desde una perspectiva que va más allá del clásico modelo de bienestar y sobre la base de la experiencia adquirida en el contexto de algunos proyectos financiados por la comunidad europea que han dado lugar a buenas prácticas y modelos de excelencia replicables en el ámbito de la innovación social también vinculada a la interculturalidad.
Vínculo triádico entre Sociología, Naturaleza y Discapacidad
Authors: Simón Medina Natalia
Published: May 2024

Observar, analizar e incorporar de forma crítica las cuestiones más relevantes de la sociedad actual es un claro propósito de la sociología, cobrando en las últimas décadas un especial interés la preocupación por el desarrollo sostenible y el cambio climático, en relación con la Naturaleza y la discriminación que genera la desigualdad social, en cuanto a las personas con discapacidad. Una forma de crear conciencia social ante estas problemáticas es a través de la educación, siendo por tanto relevante la formación académica del alumnado de los Grados de Educación en Maestro/a de Infantil y Primaria, ya que serán los futuros/as docentes en la Educación Obligatoria, teniendo en sus manos la posibilidad de concienciar a los/as niños/as que tengan en sus aulas. Este artículo describe la posibilidad de incorporar la visión ecocéntrica desde la Sociología de la Educación en los Grados de Educación y de sensibilizar ante las desigualdades sociales existentes en la sociedad en el caso concreto de las personas con discapacidad, vinculando ambas y entendiendo que, los efectos negativos de la relación de los seres humanos con la Naturaleza son más negativos si cabe, en las personas con discapacidad.
Analisis Penentuan Komponen Kritis Small Excavator Menggunakan Metode FMEA dan Diagram Pareto
Authors: Nurjanah Diah Ayu , Kusminah Imah Luluk , Rachmat Aulia Nadia , Nabella Navies
Published: May 2024

Kegiatan konstruksi meliputi tahapan pembangunan, pengoperasian, pemeliharaan, pembongkaran, dan pembangunan kembali suatu bangunan. Salah satu kegiatan konstruksi yang ada di Indonesia adalah pembangunan jalur ganda rel kereta api. Pada proyek pembangunan jalur ganda rel kereta api terdapat small excavator  A yang sering mengalami kegagalan. Excavator  tersebut digunakan pada pekerjaan galian, stripping lahan dan timbunan. Kegagalan yang terjadi dapat mengganggu pelaksanaan konstruksi dan dapat mengakibatkan perusahaan mengalami kerugian. Oleh sebab itu perlu adanya analisis terhadap komponen excavator  agar diketahui komponen kritis. Pembuatan FBD (Functional Block Diagram) bertujuan untuk menggambarkan aliran kerja dari excavator  sehingga memudahkan dalam pembuatan FMEA. Penentuan komponen kritis menggunakan metode FMEA (Failure mode and Effects Analysis) yang digunakan untuk mengidentifikasi bagaimana suatu peralatan, fasilitas, atau sistem mengalami kegagalan dan dampak yang ditimbulkannya. Metode FMEA memungkinkan penentuan peringkat risiko dengan menggunakan nilai RPN (Risk Priority Number). Hasil dari RPN dilakukan analisis menggunakan diagram pareto sehingga dapat ditentukan komponen kritis dari excavator . Komponen kritis dapat ditentukan dengan menggunakan prinsip diagram pareto yang mengikuti aturan 80-20 yang menyatakan bahwa 20% dari komponen akan mewakili 80% dari keseluruhan komponen. Penentuan RPN berdasarkan hasil wawancara bersama expert judgement. Penelitian menunjukkan bahwa pada sistem kerja exvavator terdapat 6 sub-sistem yakni sub-sistem elektrik, kendali, hidrolik, engine, lower structure, dan upper structure. Hasil dari FMEA dan diagran pareto menunjukkan bahwa terdapat 3 komponen kritis yakni komponen track shoe dengan failure mode baut shoe lepas memiliki nilai RPN 60, komponen hydraulic pump dengan failure mode seal kit regulator rusak memiliki nilai RPN 32, filter oli dengan failure mode rusak memiliki RPN 32.
Did plate tectonic changes lead to the emergence of hominid bipedalism?
Authors: Ben-Avraham Zvi , Rak Joel , Schubert Gerald , Lodolo Emanuele , Schattner Uri
Published: May 2024

When early hominids began walking upright around 6 Ma, their evolutionary course took a sharp turn. The new posture enabled physical and mental developments that had not been possible before. The factors driving the transition from quadrupedalism to bipedalism remain open. Most studies have linked this fundamental transition to environmental, topographical, geomorphological, and climatic changes that progressively transformed jungle- and forest-dominated areas of southern and eastern Africa into vast savannas, thus partitioning ecological niches. During the same timeframe, major tectonic events occurred worldwide within a relatively short geological period, due to a significant and sudden shift in the motion of the Pacific plate. In our previous work, we coined the term ripple tectonics to link a major tectonic impact to the short-term local events it caused worldwide. The ripple tectonic cascade in the Pacific around 6 Ma instigated significant environmental transformations in Africa, which ultimately catalyzed the biological evolution of early hominids towards a bipedal posture.
Convivialist multilingual education: theoretical and practical suggestions from a Norwegian perspective
Authors: Brossard Børhaug Frédérique , Manral Mallika
Published: May 2024

The article aims at exploring the use of multilingual education to build a convivialist society. The article reflects theoretically on how to combine convivialist education and multilingual education. Today’s hyperdiversity in society faces a dual challenge in accelerating and unsettling climate change. The convivialist manifesto entails five key principles namely: common naturality where humans are interdependent with nature; common humanity which must be respected in each person beyond any identity differences; common sociality, based on long-lasting and rich relationships in various human communities; legitimate individuation where the singularity of the person contributes to the common good; and eventually, creative opposition where conflicts are dealt in a fertile, peaceful and deliberative manner. These key principles are additionally subordinated to the need to control human desire for hubris and never-ending possession which represents a political alternative to material growth ideology. The concept of intertwining convivialist education and multilingual education is illustrated through a case study [Master dissertation] in a Norwegian school context focusing on the significance of mother tongue education in the school curriculum for mitigating climate change. The data for the case study was gathered by conducting focus group discussions with three mother tongue teachers and two Norwegian language teachers working in a language school for newly arrived immigrant pupils in Norway. The findings identified the limitation of the Norwegian, section 2-8, lacunas in the bilingual learning curricula and it argued for the need to strengthen mother tongue education and the role of mother tongue teachers in promoting sustainable development in the school curriculum. Based on the study’s specific contextual findings and theoretical perspectives combining convivialist and multilingual education, the article infers that promoting multilingual education in schools can help mitigate climate change, and promote biocultural diversity and build a more convivialist society. The article thus aims to suggest some practical suggestions in a Norwegian plurilingual context and furthermore, it explores an expanded theoretical frame for convivialist multilingual education.
Surgical repair of rectovaginal fistula by combined transanal and transvaginal endoscopy: a case report
Authors: He Tian , Zhang Wen , Mao Nian-fen , Bai Xuan , Zhao Lin , Yue Ke-lin , Yang Guo-qing , Rao Chun-mei , Wang Jing , Wan Ping , Guo Qiang , Zuo Zan
Published: May 2024

The common causes of rectovaginal fistula include obstetric trauma, local infection, and rectal surgery, while rectovaginal fistula following hemorrhoid surgery is extremely rare. Rectovaginal fistulae (RVF) rarely heal without intervention. Surgical treatment is usually performed, but the optimal surgical method remains controversial. The patient was a 37-year-old woman who was transferred to our hospital due to an unsuccessful repair of a rectovaginal fistula after hemorrhoid surgery in a local hospital. The next day after admission, she had prophylactic ileostomy, fecal diversion and combined treatment with cephalosporin antibiotic to create a clean postoperative area. However, there was still fecal outflow from the vagina, with no significant reduction in excretion compared to previous surgery. Digestive endoscopy confirmed a failure of the repair for rectovaginal fistula. Therefore, preventive ileostomy was continued to reduce the accumulation of bacteria in the fistula and control the inflammation. After 8 weeks, the endoscopic fistula inflammation disappeared, and the condition of endoscopic surgery was considered to be mature. Subsequently, a new surgical method combining transanal endoscopy and transvaginal endoscopy was performed. After 12 weeks of surgery, a follow-up endoscopic examination showed that the fistula had been repaired and healed. During the 1-year follow-up, no serious complication was encountered, no recurrence was found, and the repair effect was satisfactory. In conclusion, a new technique combining transanal endoscopy and transvaginal endoscopy can effectively be used for the surgical repair of rectovaginal fistula after a hemorrhoid operation.
Development and validation of an innovative headspace collection technique: volatile organic compound patterns emitted by different developmental stages of Halyomorpha halys
Authors: Karimi Ali , Gross Jürgen
Published: May 2024

Over the past two decades, several headspace collection techniques have been used to detect and identify volatile organic compounds (VOCs) emitted by plants, pests, air, and soil. Volatiles emitted by pests and infected plants are usually found at low concentrations. The important challenge is to be able to capture an exact collection of relative quantities of the relevant VOCs. Here we present an innovative headspace collecting device (HSCD) for sampling VOCs, which ensures an exact regulation of mass flow velocity and collected total gas volume allowing besides qualitative analysis of collected VOCs, an exact comparison of their relative quantities in plant or insect headspace samples. The HSCD possess six parallel odor collection systems each consisting of a digital mass flow detector and controller connected to a vacuum pump, which are mounted in a trolley suitcase, connected by tubes, and wired electrically. The programming of the channels, can be done by a digital control unit. Using the HSCD, VOCs emitted by the brown marmorated stink bug (BMSB), Halyomorpha halys, from its different developmental stages including egg, nymphal stages, nymphal exuvia, and adults were collected on thermal desorption tubes and analyzed using an automated thermal desorber connected to a gas chromatography-mass spectrometry system. Forty-five VOCs were identified in total, which mainly consisted of tridecane (4.36-69.33%), E-2-decenal (4.24-26.48%), 2-undecenal (0.63-50.03%), and E-4-oxo-2-hexenal (1.22-20.58%). The random forest analysis revealed three different chemical patterns among BMSB life stages samples. In conclusion, these results indicate that the new developed HSCD, a mobile, easy to use, and reliable instrument, has a high potential to sample relevant VOCs of a specific life stage of an insect both qualitatively and quantitatively. It was demonstrated that this information can be used for identifying specific chemical signatures, which fit to specific life stages of the BMSB, and may be used as biomarker for on-site detection of this pest e.g. in shipping containers or agricultural areas.
Efferocytosis by macrophages in physiological and pathological conditions: regulatory pathways and molecular mechanisms
Authors: Sheng Yan−Ran , Hu Wen−Ting , Chen Siman , Zhu Xiao−Yong
Published: May 2024

Efferocytosis is defined as the highly effective phagocytic removal of apoptotic cells (ACs) by professional or non-professional phagocytes. Tissue-resident professional phagocytes (“efferocytes”), such as macrophages, have high phagocytic capacity and are crucial to resolve inflammation and aid in homeostasis. Recently, numerous exciting discoveries have revealed divergent (and even diametrically opposite) findings regarding metabolic immune reprogramming associated with efferocytosis by macrophages. In this review, we highlight the key metabolites involved in the three phases of efferocytosis and immune reprogramming of macrophages under physiological and pathological conditions. The next decade is expected to yield further breakthroughs in the regulatory pathways and molecular mechanisms connecting immunological outcomes to metabolic cues as well as avenues for “personalized” therapeutic intervention.
Troxerutin suppress inflammation response and oxidative stress in jellyfish dermatitis by activating Nrf2/HO-1 signaling pathway
Authors: Liu Ran , Wang Yulian , Kuai Wenhao , Li Wenting , Wang Zengfa , Xiao Liang , Wu Jianhua
Published: May 2024

Background

Stomolophus meleagris envenomation causes severe cutaneous symptoms known as jellyfish dermatitis. The potential molecule mechanisms and treatment efficiency of dermatitis remain elusive because of the complicated venom components. The biological activity and molecular regulation mechanism of Troxerutin (TRX) was firstly examined as a potential treatment for jellyfish dermatitis.

Methods

We examined the inhibit effects of the TRX on tentacle extract (TE) obtained from S. meleagris in vivo and in vitro using the mice paw swelling models and corresponding assays for Enzyme-Linked Immunosorbent Assay (ELISA) Analysis, cell counting kit-8 assay, flow cytometry, respectively. The mechanism of TRX on HaCaT cells probed the altered activity of relevant signaling pathways by RNA sequencing and verified by RT-qPCR, Western blot to further confirm protective effects of TRX against the inflammation and oxidative damage caused by TE.

Results

TE significantly induced the mice paw skin toxicity and accumulation of inflammatory cytokines and reactive oxygen species in vivo and vitro. Moreover, a robust increase in the phosphorylation of mitogen-activated protein kinase (MAPKs) and nuclear factor-kappa B (NF-κB) signaling pathways was observed. While, the acute cutaneous inflammation and oxidative stress induced by TE were significantly ameliorated by TRX treatment. Notablly, TRX suppressed the phosphorylation of MAPK and NF-κB by initiating the nuclear factor erythroid 2-related factor 2 signaling pathway, which result in decreasing inflammatory cytokine release.

Conclusion

TRX inhibits the major signaling pathway responsible for inducing inflammatory and oxidative damage of jellyfish dermatitis, offering a novel therapy in clinical applications.
Heterologous Ad26/Ad5 adenovirus-vectored vaccines elicited SARS-CoV-2-specific antibody responses with potent Fc activities
Authors: Klingler Jéromine , Kowdle Shreyas , Bandres Juan C. , Emami-Gorizi Rozita , Alvarez Raymond A. , Rao Priyanka G. , Amanat Fatima , Gleason Charles , Kleiner Giulio , Simon Viviana , Edelstein Alexis , Perandones Claudia , Upadhyay Chitra , Lee Benhur , Hioe Catarina E.
Published: May 2024

Introduction

Antibodies against the SARS-CoV-2 spike protein are a critical immune determinant for protection against the virus. While virus neutralization is a key function of spike-specific antibodies, antibodies also mediate Fc-dependent activities that can play a role in protection or pathogenesis.

Methods

This study characterized serum antibody responses elicited after two doses of heterologous adenovirus-vectored (Ad26/ Ad5) vaccines.

Results

Vaccine-induced antibody binding titers and Fc-mediated functions decreased over six months, while neutralization titers remained stable. Comparison of antibody isotypes elicited after Ad26/Ad5 vs. LNP-mRNA vaccination and after infection showed that anti-spike IgG1 were dominant and produced to high levels in all groups. The Ad26/Ad5 vaccines also induced IgG4 but not IgG2 and IgG3, whereas the LNP-mRNA vaccines elicited a full Ig spectrum (IgM, IgG1-4, IgA1-2). Convalescent COVID-19 patients had mainly IgM and IgA1 alongside IgG1. Despite these differences, the neutralization potencies against early variants were similar. However, both vaccine groups had antibodies with greater Fc potencies of binding complement and Fcg receptors than the COVID-19 group. The Ad26/Ad5 group also displayed a greater potency of RBD-specific antibody-mediated cellular phagocytosis.

Discussion

Antibodies with distinctive quality were induced by different vaccines and infection. The data imply the utility of different vaccine platforms to elicit antibody responses with fine-tuned Fc activities.