bluuebunny/crossref_metadata_2025 huggingface dataset:
Octospora conidiophora (Pyronemataceae) – a new species from South Africa and the first report of anamorph in bryophilous Pezizales
Authors: Sochorová Zuzana , Döbbeler Peter , Sochor Michal , van Rooy Jacques
Published: June 2019

Octosporaconidiophorais described as a new species, based on collections from South Africa. It is characterised by apothecia with a distinct margin, smooth or finely warted ellipsoid ascospores, stiff, thick-walled hyaline hairs, warted mycelial hyphae and growth on pleurocarpous mossesTrichosteleumperchlorosumandSematophyllumbrachycarpum(Hypnales) on decaying wood in afromontane forests. It is the first species of bryophilous Pezizales in which an anamorph has been observed; it produces long, claviform, curved, hyaline and transversely septate conidia. Three other cryptic species ofOctosporawere detected using three molecular markers (LSU and SSU nrDNA and EF1α), but these could not be distinguished phenotypically. These are not described formally here and an informal species aggregateO.conidiophoraagg. is established for them. The new species and finds ofLamprosporacampylopodisgrowing onCampylopuspyriformisandNeottiellaalbocinctaonAtrichumandrogynumrepresent the first records of bryophilous Pezizales in South Africa.
Cacaoporus, a new Boletaceae genus, with two new species from Thailand
Authors: Vadthanarat Santhiti , Lumyong Saisamorn , Raspé Olivier
Published: June 2019

We introduce a new genus, Cacaoporus, characterised by chocolate brown to dark brown basidiomata and hymenophore, tubes not separable from the pileus context, white to off-white basal mycelium, reddening when bruised, amygdaliform to ovoid spores and dark brown spore deposit. Phylogenetic analyses of a four-gene dataset (atp6, tef1, rpb2 and cox3) with a wide selection of Boletaceae showed that the new genus is monophyletic and sister to the genera Cupreoboletus and Cyanoboletus in the Pulveroboletus group. Two new species in the genus, C.pallidicarneus and C.tenebrosus are described from northern Thailand. Full descriptions and illustrations of the new genus and species are presented. The phylogeny also confirmed the reciprocal monophyly of Neoboletus and Sutorius, which further support the separation of these two genera.
Low litter cover, high light availability and rock cover favour the establishment of Ailanthus altissima in forests in southern Switzerland
Authors: Knüsel Simon , Conedera Marco , Bugmann Harald , Wunder Jan
Published: June 2019

Future forest composition is uncertain in many areas due to climate change. The spread of non-native species adds to these uncertainties, particularly in forests recently colonised by novel tree species. To anticipate future forest composition, and thus the provision of ecosystem services, a thorough understanding of the factors influencing the establishment of non-native tree species is essential. We studied the presence and abundance of regeneration of Ailanthusaltissima (Mill.) Swingle in 89 plots on a regular grid in three sites in southern Switzerland to determine the main drivers of its establishment. All sites are located in abandoned, i.e. currently unmanaged stands of Castaneasativa Mill. Propagule pressure is caused by single mature A.altissima that colonised the area ca 40 years ago. We found high rock cover, low litter cover and high light availability to be the most important predictors for the presence of A.altissima regeneration, whereas its abundance was positively influenced by high light availability, low litter cover and high browsing on regeneration of competing species. However, the presence models performed much better than the abundance models. Interestingly, the most important factors favouring the establishment of A.altissima in recently undisturbed sites were found to be similar in a nearby site after a severe forest fire, which suggests a similar establishment strategy after a disturbance as in recently undisturbed forests. Based on our results we expect a further expansion of the species in lowland forests currently dominated by C.sativa, likely controlled primarily by light availability.
Taxonomic study of the leafhopper genus Oncopsis (Hemiptera, Cicadellidae, Macropsinae) from Sichuan Province, China with description of two new species and a key to males
Authors: Li Hu , Li Juan , Dai Ren-Huai
Published: June 2019

This paper deals with the leafhopper genusOncopsis(Macropsinae) from Sichuan Province of China, and describes and illustrates two new species,O.konkaensissp. nov.from Minya Konka (Sichuan), andO.moxiensissp. nov.from Moxi Town (Sichuan), and provides a key to males and a geographic distribution map forOncopsisspecies from Sichuan.
ESPÍRITOS COMPOSITORES E INSTRUMENTISTAS: A MÚSICA NA UMBANDA
Authors: Martelli Thaís Morelatto , Bairrão José Francisco Miguel Henriques
Published: June 2019

A umbanda é uma religião de possessão em que espíritos são venerados, incorporados e desincorporados em meio a música, geralmente composta pelo som do atabaque (instrumento de percussão) e pelo canto. Conhecidas como pontos-cantados, as canções rituais estão presentes no culto e na vida cotidiana dos médiuns, contudo pouco se sabe sobre a compreensão nativa a seu respeito. Mediante um estudo de caso etnográfico, investigou-se a concepção de música umbandista, numa perspectiva etnopsicológica. Os participantes foram dez médiuns e seis espíritos, uma vez que são considerados pelo campo sujeitos interlocutores com personalidade própria. As informações foram coletadas e analisadas com base num procedimento etnopsicanalítico que combina entrevistas semiestruturadas e observação participante com uma escuta atenta aos implícitos e às repetições discursivas e discutidos com base numa revisão da literatura. Encontrou-se que os pontos-cantados ajudam o médium a concentrar-se no mundo simbólico umbandista, podendo ser disparadores de sentimentos, sensações e pensamentos, associados aos espíritos que eles descrevem. Os médiuns percussionistas disseram que tocam sob a influência dos espíritos que os instruem a fazer movimentos corporais organizados. Conclui-se que o sujeito da musicalidade umbandista não é entendido como a pessoa que aparentemente a compõe e a executa. O termo música apenas pode ser usado mediante a subordinação do entendimento nativo do emprego ritual da sonoridade a uma concepção etnomusicológica que a inclui. O sentido geral do uso da música na umbanda é propiciar concentração mental e, portanto, entender seu papel é crucial para o desenvolvimento do conhecimento etnopsicológico a respeito do culto.
SIGNIFICADOS DO CÂNCER INFANTIL: A MORTE SE OCUPANDO DA VIDA NA INFÂNCIA
Authors: Fernandes Luana Maria de Souza , Souza Airle Miranda de
Published: June 2019

O câncer infantil apresenta 70% de chance de cura se diagnosticado precocemente, embora seja uma doença rara, e pode resultar na morte. A associação entre o câncer e a morte passa a ser conhecida pelas crianças, de alguma forma, desde o momento do diagnóstico, esse encontro é constante. Nesta pesquisa buscou-se desvelar se o tema da morte de si mesma ou de outras crianças com câncer são abordados por meio dos desenhos-estórias. A pesquisa foi desenvolvida em uma associação que presta assistência psicossocial, hospedagem, alimentação e transporte às crianças e aos acompanhantes durante o tratamento oncológico. Colaboraram com a pesquisa cinco crianças que estavam em tratamento oncológico e hospedadas na casa, sendo quatro do sexo feminino e uma do sexo masculino. Como instrumento para coleta dos dados foi utilizado entrevista semiestruturada com os responsáveis, objetivando identificar informações gerais a respeito das crianças. Posteriormente, com as crianças, foi executado o procedimento de desenho-estória, por meio de desenhos e associações verbais, introduzido por Walter Trinca, em 1972. Para análise e compreensão dos dados coletados, utilizou-se o modelo de Amedeo Giorgi. Posteriormente foram construídos dois eixos temáticos: as diversas perdas no adoecer e a morte de si e de seus companheiros de enfermaria. Os resultados desvelam que a criança busca compressão do que ocorre consigo e com o ambiente onde se encontra, lidam com a incerteza em relação ao futuro, podendo sentir a proximidade da morte e expressar seus sentimentos e emoções.
INTERVENÇÃO MUSICOTERÁPICA PARA MÃE-BEBÊ PRÉ-TERMO: UMA PROPOSTA DE INTERVENÇÃO NA UTI NEONATAL
Authors: Palazzi Ambra , Meschini Rita , Piccinini Cesar Augusto
Published: June 2019

O presente relato de experiência descreve a Intervenção musicoterápica para mãe-bebê pré-termo – IMUSP, que visa sensibilizar a mãe a cantar para seu bebê pré-termo, durante a internação na Unidade de Terapia Intensiva Neonatal. A IMUSP está prevista para oito sessões, alternadas entre sessões individuais com a mãe e sessões com mãe-bebê. Na implementação da IMUSP, a musicoterapeuta realizou a intervenção na UTINeo de um hospital público com nove mães e bebês prematuros. Foram encontrados vários desafios relativos à disponibilidade das famílias atendidas e às exigências do hospital. Em função disso, foi necessário adaptar a IMUSP, flexibilizando o número de sessões, o tipo de atividades propostas, bem como a alternância entre sessões com a mãe e com mãe-bebê. Evidências sugerem que a IMUSP contribuiu para o ‘empoderamento’ da mãe e do bebê, e para a ‘musicalidade comunicativa’ da díade, fortalecendo a interação mãe-bebê pré-termo. A IMUSP é uma intervenção de baixo custo com grande potencial de impacto a longo prazo, uma vez que, além de oferecer apoio à díade na UTINeo, orienta a mãe para que possa cantar autonomamente para seu bebê durante a internação e após a alta hospitalar. Futuros estudos são necessários para ampliar a aplicação da IMUSP e verificar os seus benefícios a curto e longo prazo para a mãe, o bebê pré-termo e a interação mãe-bebê.
AUTORIDADE E TRANSFERÊNCIA: NOTAS SOBRE O CASTELO BRANCO, DE O. PAMUK
Authors: Rabêlo Fabiano Chagas , Martins Osvaldo Costa , Martins Karla Patrícia Holanda
Published: June 2019

Esta é uma pesquisa bibliográfica, em formato de ensaio, que comenta o livro de O. Pamuk O castelo branco. A partir dele, busca-se esclarecer as condições históricas, culturais e epistêmicas de realização do discurso analítico, interrogando o uso da autoridade na técnica analítica em comparação com outras modalidades de laço social. As categorias de análise adotadas são as contribuições de Koyré sobre a construção do método científico moderno, as elaborações de Lacan sobre o sujeito da ciência, sua teoria dos discursos e os conceitos de transferência, estranho e narcisismo das pequenas diferenças. Salienta-se que o texto de Pamuk possui como centro a problematização do sentimento do estranho entre dois sósias em uma relação fortemente marcada pela distância cultural, a rivalidade e a admiração. Discute-se, em seguida, a participação do sujeito do inconsciente no ato de conhecer e a influência do narcisismo na produção de obstáculos no campo do saber. Salienta-se que, ao não intervir por meio de seus próprios significantes e Ideal de Eu, o psicanalista evidencia a relação do sujeito com seus significantes mestres e seu objeto causa do desejo. A psicanálise vem demostrar por essa via que a injunção social de se colocar no lugar do outro é atravessada pelas contradições do narcisismo das pequenas diferenças. Ao final, indaga-se por meio do sentimento do estranho como móbil da segregação e da violência o que há do outro em mim que eu rejeito.
A Computational Study on Structural and Electronic Properties of 1-(4-Chlorophenyl)-2-{[5-(4-Chlorophenyl)-1,2,3-Oxadiazol-2-Yl]Sulfanyl}Ethanone
Authors: Toh Pek Lan , Meepripruk Montha , Rasmidi Rosfayanti
Published: June 2019

In this paper, a first principle Density Functional Theory (DFT) method was conducted to study the geometric and electronic structures of 1-(4-chlorophenyl)-2-{[5-(4-chlorophenyl) -1,3,4-oxadiazol-2-yl] sulfanyl} ethanone, C16H10Cl2N2O2S. Using B3LYP level of theory with four basis sets of 6-31G**, 6-31++G**, 6-311G**, and 6-311++G**, the equilibrium structure of the title molecule was used to determine the total energies, Frontier molecular orbital’s energies, Mulliken atomic charges, and others. The computed findings present that four total energies obtained are close to each other, with the corresponding values of-59716.06 eV, -59709.42 eV, -59708.56 eV, and-59716.51 eV, respectively for B3LYP/6-31G**, B3LYP/6-31++G**, B3LYP/6-311G**, and B3LYP/6-311++G** methods. The calculated HOMO-LUMO energy gaps were predicted in the range of 4.001 eV - 4.089 eV. In this study, the atomic charge values of molecular system were also determined using Mulliken Population Analysis (MPA) approach. For DFT/B3LYP/6-311G** level of calculation, the computed results show that the atom of C8 accommodates the highest negative charge in the title molecular system. All the oxygen, nitrogen, and chloride atoms are having negative charges, whereas all the hydrogen atoms are having positive charges. In addition, the dipole moment value was also determined to be 1.4758 Debye by employing DFT/B3LYP/6-311G** level of theory.
Field Programmable Gate Array (FPGA) Based Microwave Oven
Authors: Bhuvaneswari Thangavel , Abdul Aziz Nor Hidayati , Hossen Jakir , Venkataseshaiah Chinthakunta
Published: June 2019

In this paper, an FPGA-based microwave oven controller design which can be implemented using Altera DE1 development board is presented. The motivation for this work is to explore FPGA for real time applications. First, a microwave oven controller design architecture that could fit into Altera DE1 board, utilizing on-board peripherals is developed. Then, using the proposed architecture, the design is implemented using Verilog HDL. The microwave oven functionalities are demonstrated using Altera DE1 development board by means of Quartus II 13.0 software. The testbenches are created and waveforms are generated using Modelsim 10.1d software. The simulation results for various cases have been presented and the results confirmed that all the basic functionalities of a practical microwave oven can be realized. The proposed FPGA based controller has a high potential for incorporation in microwave ovens.
MHD Stagnation-Point Flow of a Nanofluid Past a Stretching Sheet with a Convective Boundary Condition and Radiation Effects
Authors: Mohd Nasir Nor Ain Azeany , Ishak Anuar Mohd , Pop Ioan
Published: June 2019

In this paper, the investigation of magnetohydrodynamic (MHD) stagnation point flow of a nanofluid past a stretching sheet with a convective boundary condition and radiation effects is carried out numerically. Similarity transformation is used to reduce the governing partial differential equations into third and second order non-linear ordinary differential equations. These equations are then being solved numerically using a problem solver built in the MATLAB software. The numerical solutions for the skin friction coefficient, local Nusselt number, velocity and temperature profiles for different values of the physical parameters are presented graphically and discussed further. The results indicate that the velocity and the temperature are influenced by the magnetic parameter M, Brownian motion parameter Nb and radiation parameter Nr. The local Nusselt number and the skin friction coefficient are affected significantly in the presence of suction at the boundary.
Numerical Solution of Volterra Integro-Differential Equations Using Improved Runge-Kutta Methods
Authors: Rabiei Faranak , Abd Hamid Fatin , Md Lazim Nafsiah , Ismail Fudziah , Abdul Majid Zanariah
Published: June 2019

In this paper, we proposed the numerical solution of Volterra integro-differential equations of the second kind using Improved Runge-Kutta method of order three and four with 2 stages and 4 stages, respectively. The improved Runge-kutta method is considered as two-step numerical method for solving the ordinary differential equation part and the integral operator in Volterra integro-differential equation is approximated using quadrature rule and Lagrange interpolation polynomials. To illustrate the efficiency of proposed methods, the test problems are carried out and the numerical results are compared with existing third and fourth order classical Runge-Kutta method with 3 and 4 stages, respectively. The numerical results showed that the Improved Runge-Kutta method by achieving the higher accuracy performed better results than existing methods.
Spatial Signature Algorithm (SSA): A New Approach in Countermeasuring XML Signature Wrapping Attack
Authors: Saudi Madihah Mohd , Mohd Zaizi Nurzi Juana , Bakar Azreena Abu , Ahmed Swessi Khaled Juma
Published: June 2019

This paper introduces a new approach in countermeasuring XML signature wrapping attack called the Spatial Signature Algorithm (SSA). The motivation for proposing the SSA approach is due to the limitation of the SOAP (Simple Object Access Protocol) in handling the XML signature wrapping attacks. A different strategy is to be planned in order to deter such attack without extensive computational expense. Spatial Signature Algorithm builds upon the notion of ratio signature that is recommended by a research in biotechnology. The research suggests the possibility of diagnosing a specific disease based on the idea of ratios, specifically on the comparative relationship between elements to detect the emergence of certain threats. Bridging this notion to security, the principle of using space and ratio to detect abnormality is extended to the application of spatial information and digital signature to detect and combat the XML wrapping signature attack.
Using PERT to Optimise the Completion Time of Air-Conditioning and Mechanical Ventilation (ACMV) Project
Authors: Pang Chuan Kian , Mohd-Lair Noor Ajian , Chua Yi Sheng
Published: June 2019

An air-conditioning and mechanical ventilation (ACMV) construction project involved many interrelated construction activities with varying durations and multiple dependencies. This paper focuses on the development of a best possible project planning and scheduling technique that can help the project manager to manage and complete the ACMV project in optimal time. The program evaluation and review technique (PERT) is used in this research. The PERT technique helps to determine the probabilities of various stages of the project by specified deadlines and identify the activities on the critical path that have high potential for causing delays in the project completion time. The completion times of 72, 76, 79, and 80 weeks were taken for the PERT analysis. Deadline of 72 weeks is the contractual period of the ACMV project as specified in the contract. Completion time of 76 weeks is the critical path of the project as analyzed by the PERT technique. The deadline of 79 weeks is the proposed completion time for the ACMV project whereas 80 weeks are the actual completion date of the project. The PERT analysis revealed that the project completion time of 72 weeks, which is as stated in the contractual completion time, yielded the probability of completion of 2.67% only. This analysis shows that the contractual period is impossible to be achieved and it is an unrealistic time setting. Further negotiation is required including changing or extending of the contractual completion time. The other completion times are able to be achieved but the company may need to face the high penalty costs due to the delays in completion time.
Variables Influencing Machine Learning-Based Cardiac Decision Support System: A Systematic Literature Review
Authors: Rahman Mohammed Ashikur , Tumian Afidalina
Published: June 2019

Now a day, clinical decision support systems (CDSS) are widely used in the cardiac care due to the complexity of the cardiac disease. The objective of this systematic literature review (SLR) is to identify the most common variables and machine learning techniques used to build machine learning-based clinical decision support system for cardiac care. This SLR adopts the Preferred Reporting Item for Systematic Review and Meta-Analysis (PRISMA) format. Out of 530 papers, only 21 papers met the inclusion criteria. Amongst the 22 most common variables are age, gender, heart rate, respiration rate, systolic blood pressure and medical information variables. In addition, our results have shown that Simplified Acute Physiology Score (SAPS), Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE) are some of the most common assessment scales used in CDSS for cardiac care. Logistic regression and support vector machine are the most common machine learning techniques applied in CDSS to predict mortality and other cardiac diseases like sepsis, cardiac arrest, heart failure and septic shock. These variables and assessment tools can be used to build a machine learning-based CDSS.
Adaptive and Dynamic Hybrid Model for Software Project Management: A Review on its Clarity and Usage to Improve Project Success
Authors: Jabar Marzanah A. , Ali Norhayati Mohd. , Jusoh Yusmadi Yah , Abdullah Salfarina , Mohanarajah S.
Published: June 2019

Software developers have shown a lot of interest in using agile approaches and methods to manage projects. The Agile Manifesto in 2001 provided a good basis to use this as it formulated its 4 values and 12 principles. Adaptability was a common feature in the Agile Manifesto to make agility happen and there appears a need to combine dynamism to ensure agility takes a more concrete and effective role. Whilst the term adaptability is discussed more often than dynamism by most researchers, the clarity in its meaning needs improvement as the terms are used interchangeably. This paper proposes a useful clarity on its differences and how it should be used. In addition, this approach would also facilitate the current research interest in mixing and combining software development methodologies to create hybrid versions as pure methods (traditional and agile) have not worked well in most software projects.
Adaptive Neuro-Fuzzy Inference System for Predicting Compressive Strength of Fibres Self Compacting Concrete
Authors: Meesaraganda L.V. Prasad , Saha Prasenjit
Published: June 2019

This research focused on the applicability of Adaptive Network-Based Fuzzy Inference System (ANFIS) for predict the compressive strength of fibers self-compacting concrete. An ANFIS model combines the benefit of ANN and fuzzy logic. The data developed experimentally for fibers self-compacting concrete and the data sets of a total 99 concrete samples were used in this work. In this paper research is computational based for prediction of concrete compressive strength. A model was developed using ANFIS with five input nodes as w/p ratio, course aggregate, fine aggregate, fiber and superplastizers. In this model Feed-forward three-layer back-propagation neural networks with 10 hidden nodes were examined using learning algorithm. ANFIS model proposed analytically that gives more compatible results. Hence, the model is adopted to predict the strength of fibrous self-compacting concrete.
Validation of microwave-assisted sample extraction-high performance liquid chromatography (HPLC) method for quantitative analysis of hydrolysed amino acids in aquatic biological samples
Authors: Jayasinghe G.D.T.M. , Jinadasa B.K.K.K.
Published: June 2019

A sensitive and widely applicable High-Performance Liquid Chromatography (HPLC) with fluorescence detector (FLD) method for determination hydrolysed amino acids in fish and aquatic products was developed and validated through study. The method involved a microwave-assisted sample extraction and protein hydrolysed with the hydrochloric acid and propionic acid. The separation was performed by Shim-pack HR-ODS column with a gradient mobile phase. The total separation time was 25 min per run. The method showed satisfactory linearity, repeatability, accuracy, and limit of detection for 21 amino acids with the 1-100 mg/L calibration range based on 10 µL injection. The fish, fish feed, canned fish and seaweeds samples were analysed successfully by using this developed method.
Protease-Activated Receptor 2 Agonist as Adjuvant: Augmenting Development of Protective Memory CD8 T Cell Responses Induced by Influenza Virosomes
Authors: Zhou Gang , Hollenberg Morley D. , Vliagoftis Harissios , Kane Kevin P.
Published: June 2019

Protease-activated receptor 2 (PAR-2) is expressed in various tissues, including lung, and when activated, promotes inflammation, differentiation, and migration of dendritic cells. We found that combining influenza virosomes containing hemagglutinin and neuraminidase with a PAR-2 agonist peptide (PAR-2AP) in an intranasal prime boost approach increased survival of mice challenged weeks later with lethal influenza virus over that by virosome or PAR-2AP prime boost alone. No weight loss occurred from influenza challenge after virosome-plus–PAR-2AP prime boost compared with either virosomes or PAR-2AP alone. Thus, virosomes plus PAR-2AP prevented morbidity as well as mortality. Through adoptive transfer, CD8+ lung T cells but not CD4+ T cells from virosomes plus PAR-2AP–primed mice protected from lethal influenza virus challenge and enhanced survival with less weight loss and faster recovery. Virosome-plus–PAR-2AP prime boost resulted in greater percentages of T effector memory phenotype cells (Tem) in lung, and higher frequencies of CD8 Tem and T central memory cells displayed effector functions in response to virus challenge in vivo. Virosome-plus–PAR-2AP prime boost also resulted in greater percentages of Ag-specific CD8+ T cells, both Tem and T central memory cells, in lungs of animals subsequently challenged with live influenza virus. Our findings indicate that PAR-2AP, a short peptide, may be a new and useful mucosal adjuvant.
Cytokine Diversity in Human Peripheral Blood Eosinophils: Profound Variability of IL-16
Authors: Ma Michelle , Percopo Caroline M. , Sturdevant Daniel E. , Sek Albert C. , Komarow Hirsh D. , Rosenberg Helene F.
Published: June 2019

Eosinophilic leukocytes develop in the bone marrow and migrate from peripheral blood to tissues, where they maintain homeostasis and promote dysfunction via release of preformed immunomodulatory mediators. In this study, we explore human eosinophil heterogeneity with a specific focus on naturally occurring variations in cytokine content. We found that human eosinophil-associated cytokines varied on a continuum from minimally (coefficient of variation [CV] ≤ 50%) to moderately variable (50% < CV ≤ 90%). Within the moderately variable group, we detected immunoreactive IL-27 (953 ± 504 pg/mg lysate), a mediator not previously associated with human eosinophils. However, our major finding was the distinct and profound variability of eosinophil-associated IL-16 (CV = 103%). Interestingly, eosinophil IL-16 content correlated directly with body mass index (R2 = 0.60, ***p < 0.0001) in one donor subset. We found no direct correlation between eosinophil IL-16 content and donor age, sex, total leukocytes, lymphocytes, or eosinophils (cells per microliter), nor was there any relationship between IL-16 content and the characterized −295T/C IL-16 promoter polymorphism. Likewise, although eosinophil IL-1β, IL-1α, and IL-6 levels correlated with one another, there was no direct association between any of these cytokines and eosinophil IL-16 content. Finally, a moderate increase in total dietary fat resulted in a 2.7-fold reduction in eosinophil IL-16 content among C57BL/6-IL5tg mice. Overall, these results suggest that relationships between energy metabolism, eosinophils, and IL-16 content are not direct or straightforward. Nonetheless, given our current understanding of the connections between asthma and obesity, these findings suggest important eosinophil-focused directions for further exploration.
A Novel Animal Model of Emphysema Induced by Anti-Elastin Autoimmunity
Authors: Gu Bon-Hee , Sprouse Maran L. , Madison Matthew C. , Hong Monica J. , Yuan Xiaoyi , Tung Hui-Ying , Landers Cameron T. , Song Li-Zhen , Corry David B. , Bettini Maria , Kheradmand Farrah
Published: June 2019

Loss of immune tolerance to self-antigens can promote chronic inflammation and disrupt the normal function of multiple organs, including the lungs. Degradation of elastin, a highly insoluble protein and a significant component of the lung structural matrix, generates proinflammatory molecules. Elastin fragments (EFs) have been detected in the serum of smokers with emphysema, and elastin-specific T cells have also been detected in the peripheral blood of smokers with emphysema. However, an animal model that could recapitulate T cell–specific autoimmune responses by initiating and sustaining inflammation in the lungs is lacking. In this study, we report an animal model of autoimmune emphysema mediated by the loss of tolerance to elastin. Mice immunized with a combination of human EFs plus rat EFs but not mouse EFs showed increased infiltration of innate and adaptive immune cells to the lungs and developed emphysema. We cloned and expanded mouse elastin-specific CD4+ T cells from the lung and spleen of immunized mice. Finally, we identified TCR sequences from the autoreactive T cell clones, suggesting possible pathogenic TCRs that can cause loss of immune tolerance against elastin. This new autoimmune model of emphysema provides a useful tool to examine the immunological factors that promote loss of immune tolerance to self.
Participation restrictions and vocational rehabilitation needs experienced by persons with a unilateral lower limb amputation in the Western Cape, South Africa
Authors: Yu Tak Wing , Ennion Liezel
Published: June 2019

Background: Vocational rehabilitation (VR) aims to rehabilitate a person with an amputation back into actively participating in society. Even though lower limb amputation (LLA) surgery is commonly performed in South Africa (SA), little research has been published on the participation restrictions experienced by and vocational needs of persons with LLA in the Western Cape (WC).Objectives: The aim of this study was to determine and explore the participation restrictions and VR needs of persons with a unilateral LLA in the WC.Method: A mixed-methods approach and a sequential exploratory design were utilised to collect data from 50 persons with an LLA. Participants were conveniently sampled within the Cape Metropole region of the WC, SA. The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) tool was used to collect the quantitative data, and telephonic interviews were conducted for qualitative data collection.Results: A third (28%) of participants in this study were unemployed, and only 14% (n = 7) of the participants owned or used a prosthesis. In addition, 50% of the participants either had a disability grant or were on pension. The participation restrictions identified were mainly related to mobility where 74% (n = 37) of participants had extreme difficulty with mobility in general, 92% (n = 46) struggled with walking distances longer than 1 km and 80% (n = 40) had extreme difficulty in completing household tasks quickly. The main VR needs identified in this study were the inadequate rehabilitation services that target ambulation (standing and walking) to facilitate employment.Conclusion: Persons with a unilateral LLA still experience significant difficulties in mobility 3 months post-amputation, which negatively affects their participation in society and vocational activities.
Nuclear magnetic resonance on $LaFeAsO_{0.4}H_{0.6}$ at 3.7 GPa
Authors: Fujiwara N. , Takeuchi M. , Kuwayama T. , Nakagawa S. , Iimura S. , Matsuishi S. , Hosono H.
Published: June 2019

A prototypical electron-doped iron-based superconductor $LaFeAsO_{1-x}H_x$ undergoes an antiferromagnetic (AF) phase for $x  \geq 0.49$. We performed NMR measurements on $LaFeAsO_{0.4}H_{0.6}$ at 3.7 GPa to investigate the magnetic properties in the vicinity of a pressure-induced QCP. The linewidth of $~^1H$-NMR spectra broadens at low temperatures below 30 K, suggesting that the ordered spin moments remain at 3.7 GPa. The coexistence of gapped and gapless spin excitations was confirmed in the ordered state from the relaxation time $T_1$ of $~^{75}As$. The pressure-induced QCP is estimated to be 4.1 GPa from the pressure dependence of the gapped excitation.

 

Edited by: A. Goñi, A. Cantarero, J. S. Reparaz
PADRÕES DE CRESCIMENTO DOS MUNICÍPIOS E A REPRESENTATIVIDADE INDUSTRIAL EM GOIÁS. (2005 A 2015)
Authors: Arriel Marcos Fernando , Godoi Cintia Neves , De Castro Sergio Duarte
Published: June 2019

Os padrões de crescimento dos municípios goianos e as relações existentes com a representatividade de suaatividade industrial no intervalo de tempo de 2005 a 2015 são o objeto de análise deste estudo. Pretendeseidentificar os municípios que formam os aglomerados industriais em Goiás e associar, espacialmente, opadrão de crescimento desses municípios e o peso do setor industrial. Dentre os resultados principais, podese destacar que as atividades industriais, especialmente representadas pelas indústrias de transformação e extrativa mineral, proporcionaram ganhos para a expansão da economia goiana e para um conjunto expressivo de municípios. Os resultados também mostraram que o desempenho de um conjunto de municípios foi afetado pela crise econômica brasileira, sobretudo em municípios cujas atividades principais estavam ligadas à commodities minerais, metalmecânica e à produção de medicamentos.Palavras-chave: Municípios goianos. Indústria de transformação. Indústria extrativa mineral. Padrão decrescimento.
Comparative study of some bioactive compounds and their antioxidant activity of some berry types
Authors: Aly Amina , Maraei Rabab , Abou El-Leel Omneya
Published: June 2019

Berries are wealthy in bioactive compounds like phenolic compounds and flavonoids that are deemed antioxidants and are great important to health. This research was performed to examine, recognize and compare bioactive compounds in certain types of berries and their antioxidant activity. The data show that blue berry, black berry and Egyptian black mulberry contain the highest content of most bioactive compounds such as phenolic compounds, flavonoids and tannins, while long mulberry and red currant berry have the lowest content for most of these compounds. They therefore, contain the highest value of antioxidant activity. The chemical composition of the berries varies depending on cultivar, variety, location of growth, environmental conditions and harvest time, as well as post-harvest treatments therefore the composition differed from berry fruit to another. Thus, berry fruits are very useful in nutrition to protect the body from many diseases because of its containment of these compounds, which act as free radicals scavenger that harm the body and thus rid the body of many harmful toxins.
Convergence of a two-parameter family of conjugate gradient methods with a fixed formula of stepsize
Authors: Khelifa Bouaziz , Yamina Laskri
Published: June 2019

We prove the global convergence of a two-parameter family of conjugate gradient methods that use a new and different formula of stepsize from Wu \cite% {14}. Numerical results are presented to confirm the effectiveness of the proposed stepsizes by comparing with the stepsizes suggested by Sun and his colleagues \cite% {2, 12}.\\
Producción de tilapia (Oreochromis niloticus L.) en la etapa de engorde con dos estrategias de alimentación
Authors: Paz Patricio E , Martinez Turcios Alejandra Danelia , Chávez Chávez José Ignacio
Published: June 2019

La tilapia gris (Oreochromis niloticus L.) es una excelente opción para la producción acuícola debido a su resistencia a condiciones adversas, enfermedades y sus hábitos alimenticios. Se evaluaron dos estrategias de alimentación durante la etapa de engorde, la cual finaliza al alcanzar un peso ideal de 1,085 g a la cosecha. Las estrategias de alimentación fueron ad libitum y alimentación al 90 % del ad libitum. El ensayo se realizó en AquaFinca Saint Peter Fish, Cortés, Honduras. Las variables medidas fueron: índice de conversión alimenticia (ICA), índice de alimentación (IA), días a cosecha (Decos) y ganancia de peso diario (GDP).  Las unidades experimentales fueron doce jaulas flotantes, seis jaulas ad libitum y seis jaulas con el 90 % del ad libitum; cada jaula tenía un volumen de 1,380 m3 con una capacidad de 50,000 peces. El análisis estadístico se realizó por medio de una prueba t (P ≤0.05). La alimentación ad libitum y al 90 % del ad libitum no presentaron diferencias en ICA (1.88 y 1.82 respectivamente), tampoco se presentaron diferencias en GDP con 6.39 g ad libitum y 6.16 g con 90 % del ad libitum. El tratamiento ad libitum presentó un IA de 3.19 y el 90 % del ad libitum de 3.06; Decos fueron 157 y 165 respectivamente. El tratamiento al 90 % del ad libitum, además de representar un ahorro en alimento no tuvo efecto sobre el ICA, pero si se retrasó ocho días para llegar al peso ideal de cosecha con una diferencia de 26,270 kg de alimento entre ambos tratamientos.
El movimiento estudiantil en la cultura política de país: experiencias en gobernanza y toma de decisiones
Authors: Andino Paiz Luis Manuel
Published: June 2019

El presente trabajo tiene como finalidad realizar un análisis del comportamiento en lo que respecta a la cultura política, en la comunidad universitaria nicaragüense durante la segunda mitad del triunfo de la Revolución Popular Sandinista. Muchas veces se ha hablado de las luchas históricas del movimiento estudiantil, el antagonismo a la dictadura de los Somoza, la defensa de la Revolución, la lucha por el 6%, constitucional que no se vislumbraba únicamente en cubrir aranceles, y pago a los docentes, sino que iba más allá. Se buscaba una base material económica que permitiera la supervivencia de la Universidad de una forma justa, racional, participativa, democrática y accesible al pueblo.
Gregorio Smutko y Alejandro Dávila Bolaños: Pioneros de estudios culturales e indigenista en Nicaragua
Authors: Alvarez Arzate María Dolores
Published: June 2019

El texto presenta detalles esbozados de las obras literarias y científicas de dos grandes científicos que dedicaron su trayectoria profesional a documentar la cultura, los orígenes, los pueblos originarios y las toponimias nicaragüenses. Padres de los estudios de la cultura caribeña y toponimias nicaragüenses. Este 2019, el Departamento de Antropología de la UNAN-Managua está dedicando el XII Congreso Centroamericano de Antropología, de la RED Centroamericana de Antropología a estos dos célebres científicos.
Bioenhancing effects of naringin on atrovastatin
Authors: Venkatesh Sama , Pagilla Balaraju , Chiluka Rajeswari , Alvala Ravi , Pola Ravi Kumar , Mullangi Ramesh
Published: June 2019

Naringin (CAS no: 10236-47-2) is a flavonone glycoside obtained from Citrus paradisi (grapefruit), a natural bioenhancer and reported to enhance the bioavailability of drugs by inhibiting cytochrome P450 and P-glycoprotein (P-gp). The aim of the present study was to investigate the effect of naringin on antihyperlipidemic properties of atorvastatin (AST) in tyloxapol induced hyperlipidemic rats and the effects were supported with measurement of plasma concentrations of AST by HPLC method. Animals received AST along with naringin (15 and 30 mg/kg) shown higher percent reduction in both cholesterol and triglycerides levels, when compared to animals received AST alone at dose of 25 and 50 mg/kg and it was found that the higher percent reduction in cholesterol and triglycerides was proportional to increase in plasma concentration of AST. From the results it is evident that the co-administration of naringin along with AST increased the plasma concentration of AST. The findings of the present study confirmed that naringin could be used as bioenhancer. The co-administration of AST and the diet with naringin (grapefruit) to the patients may potentiate the therapeutic efficacy of AST.
Nekrotizan Fasiit: Vitamin D eksikliği predispozan bir faktör olabilir mi? Olgu sunumu
Authors: BEKDAŞ Mervan , GÖKKAYA Ali
Published: June 2019

Nekrotizan Fasiit (NF), subkutan doku ve fasiya nekrozu ile kendini gösteren bakteriyel bir yumuşak doku enfeksiyonudur. Hızlı ilerleyen bir tablo olması nedeniyle erken tanı hayat kurtarıcıdır. Daha önceden sağlıklı olan 12 aylık kız hasta 2 gün önce başlayan ateş, sağ kasık bölgesinde kızarıklık ve şişlik nedeniyle hastanemize getirildi. Başlanan uygun tedaviye rağmen lezyonlar iki taraflı lomber bölge, sırt ve göğüs yan duvarına yayılınca hastada nekrotizan fasiit düşünüldü, takibinin 36. saatinde fasiyotomi insizyonu ile tüm nekrotik dokuların drenajı yapıldı. Uyluk fasiyo-kutan flepler defektlerin onarımı için kullanıldı. 25 (OH) vitamin D seviyesi 2.4 ng/ml saptanınca 10.000 IU/kg D vitamini oral yoldan verildi. 16. gününde hasta taburcu edildi. 4. ayındaki kontrolde yaraların belirgin olarak düzeldiği görüldü. Antimikrobiyal aktivitesi olan D vitamininin, yara iyileşmesini de hızlandıran bir özelliği olduğu kabul edilmektedir. Hastamızda D vitamini replasmanının iyileşmeyi olumlu yönde etkilediğine inanıyoruz. Değişik predispozan risk faktörleri olmasına rağmen, literatürde vitamin D eksikliği ile ilişkili NF’ye dair bir yayın tespit edemedik. Vitamin D eksikliğinin de NF için kolaylaştırıcı bir faktör olabileceğine dikkat çekmek için bu olguyu sunmayı amaçladık. 
Os pronunciamentos da presidente Dilma Rousseff (PT) no Dia do Trabalhador nos anos de 2014 e 2015: memórias e silenciamentos no processo de construção de imagem
Authors: Oliveira Luiz Ademir de , Mira Gustavo Fernandes Paravizo , Leal Paulo Roberto Figueira
Published: June 2019

O artigo discute a relação entre capital político e visibilidade midiática a partir da análise das estratégias de comunicação da ex-presidente Dilma Rousseff (PT) em seus pronunciamentos no Dia do Trabalhador. Foram tomados como recortes o discurso feito em 2014 em Cadeia Nacional de Rádio e Televisão (CNRT) e os pronunciamentos de 2015 postados nas redes sociais. Em função da baixa popularidade da petista neste segundo momento, a fala foi veiculada apenas na internet, evitando a superexposição na mídia massiva. Com isso, o governo pretendia evitar uma possível onda de manifestações similares às ocorridas no pronunciamento em CNRT no Dia Internacional da Mulher, no dia 8 de março de 2015, quando ocorreram os primeiros “panelaços”. Com base na Análise de Discurso francesa, busca-se compreender, em perspectiva comparativa, os mecanismos discursivos que emergiram nas falas da presidente nos dois momentos.
Seriam as velhas ainda mulheres? Reflexões sobre gênero, (não) velhice e biopoder a partir de capas de Veja e Tpm
Authors: Machado Felipe Viero Kolinski , Trindade Vanessa Costa
Published: June 2019

A partir da análise de capas específicas de Veja (edição 2121, de 15 de julho de 2009) e Tpm (edição 125, de outubro de 2012) buscamos compreender como tais dispositivos discursivos e pedagógicos atuam no controle do corpo feminino e, notadamente, em seu processo de (não) envelhecimento. Inscritos numa lógica da biopolítica, os corpos aí estampados restringem as possibilidades de existência que poderiam ser múltiplas. Essas revistas e suas capas configuram-se como manuais de orientação e aconselhamento sobre como tornar-se e, ainda, manter-se mulher. Referenciando-nos em seu texto verbo-visual, e em discussões teóricas que faz tempo apontam para a juventude como “adequada” e para a velhice como um processo de degeneração, perguntamos: as velhas continuam sendo mulheres?
O “lugar” das Relações Públicas na Indústria Criativa
Authors: Martins Tiago Costa
Published: June 2019

A comunicação encontra, na indústria criativa, um campo profícuo para discussões científicas. Às relações públicas a problemática recai em percebê-la enquanto ciência ou arte e em posicioná-la na indústria criativa. A presente pesquisa, exploratória, bibliográfica e documental objetiva perceber tal posicionamento, discutindo a metodologia do Department for Culture, Media and Sport do Reino Unido. Conclui-se o artigo argumentando que as relações públicas, a partir das práticas, da ocupação profissional e da atividade econômica, são creative service providers da indústria criativa.
Redes sociais online e democracia monitorada: sobre comentários monitores a instituições brasileiras no Facebook
Authors: Carvalho Fernanda Cavassana de , Cervi Emerson Urizzi
Published: June 2019

O artigo discute formas contemporâneas de relacionamento de cidadãos com instituições democráticas dentro do contexto das redes sociais online. Para isso, são consideradas as publicações e as interações registradas em fanpages que alimentam o debate público no Facebook. Foram selecionadas doze instituições brasileiras, de diferentes dimensões de representação e níveis de institucionalização. Seus 37.807 posts e 12.995.826 comentários formam o corpus, sendo o recorte temporal de sete meses, em 2017. A metodologia de análise é quantitativa e comparativa. Os resultados apontam uma tendência do comportamento monitor na fanpage ocorrer quanto maior for o nível de institucionalização da instituição. Também indicam, comparativamente, um nível fraco de engajamento do público com as fanpages dos partidos políticos.
Gestão da cadeia de suprimentos: análise do desempenho ambiental de fornecedores verdes por meio do método fuzzy TOPSIS
Authors: Miranda Bruno , Prato Neto Cyro Rei , Patias Jovani , Ferreira Alexandre , Godoy Leoni
Published: June 2019

Há um grande interesse por parte das organizações pela adoção de práticas sustentáveis, visando melhorar o desempenho de suas cadeias de suprimentos. Regulamentos ambientais, consumo de recursos e descarte de resíduos são alguns dos fatores que podem influenciar na tomada de decisão quanto a contratação de fornecedores verdes. Este estudo ilustra o caso de um fabricante de implementos agrícolas do setor metal mecânico que busca implementar o gerenciamento da cadeia de suprimentos verdes (GSCM) e selecionar um fornecedor que atenda aos requisitos ambientais determinados. Portanto, o objetivo desta pesquisa consiste em avaliar o desempenho ambiental de três potenciais fornecedores por meio do método de tomada de decisão multicritério fuzzy TOPSIS e selecionar a melhor alternativa. Além disso, é realizada uma análise de sensibilidade para comprovar a robustez do método utilizado. O resultado mostra que o fornecedor A3 ocupa o primeiro lugar entre os três fornecedores avaliados, demonstrando um forte desempenho ambiental, sobretudo, em quatro critérios: parceiros ambientais, imagem verde, reciclagem e descarte de resíduos.
Conhecimento e sentimentos das mulheres climatéricas sobre a doença coronariana
Authors: Mamede Marli Villela , Silva Líscia Divana Carvalho , Oliveira Bruna da Silva
Published: June 2019

Objective: this is a qualitative study aimed at describing the impact of the discovery of thecoronary disease in the daily life of climacteric women. Method: Bardin content analysiswas used for data interpretation. Results and discussion: four categories were identified:“knowledge of the coronary disease”; “Change in food”; “Changes in work”; “Insecurityand fear of death”. The women showed a lack of knowledge in defining the coronarydisease. They understand that it is a serious and risky disease, but they find it difficultto define or explain it. They recognize the importance of the recommended treatment,following the therapeutic recommendations as to the change of habits of life, the useof the drug therapy and the invasive treatments, as the surgery of revascularization ofthe myocardium and the angioplasty. Conclusion: the main changes in the daily lifeof women are related to food and work and domestic activities. The loss of autonomyimposed by the disease causes dependence and uselessness. Insecurity and fear are alsopresent associated with symbolic meanings of unexpected and death. The daily changesafter the discovery of the coronary disease cause physical, emotional and social impactto these women, quite harmful to their health in the recurrence of coronary events or toa more serious and incapacitating condition of the coronary disease.