bluuebunny/crossref_metadata_2025 huggingface dataset:
The improvement of insulin resistance and the antioxidant capacity in type 2 diabetes mellitus rats with whiteleg shrimp shell powder (Litopenaeus vannamei)
Authors: Ahriyasna Risya , Agustini Tri Winarni , Djamiatun Kis , Primal Def
Published: August 2021

As estimated having an increased incidence of about 50% until 2040, the diabetic condition could be augmented primarily from astaxanthin contained in carotenoids. This research examines and compares the influence of WSSP and AST complement on Homeostatic Model Assessment-Insulin Resistance (HOMA-IR) level and Total Antioxidant Capacity (TAC) induced high-fat diet streptozotocin (HFD-STZ) in T2DM rats. WSSP 0.89gr/200gr/d (X1) and 1.77gr/200gr/d (X2) groups; and AST supplement 0.09mg/200gr/d (X3) groups were compared with both of positive (K1) and negative (K2) groups. The treatments were administered orally for 21 days to 25 Wistar rats which each group consisted of 5 rats. HOMA-IR and TAC levels were measured by ELISA and ABTs method respectively. TAC levels significantly increased in treatment groups than K1 group (p = 0.008). The increase in the TAC level of the X2 group was greater than the X1 group (p = 0.017). HOMA IR levels were significantly lower in treatment groups than K1 group (p = 0.009). X2 group had a greater decrease in HOMA IR levels compared to X1 (p = 0.016). In consequence, the research findings show a utilitarian effect of WSSP in increasing TAC and decreasing the HOMA-IR index.
HUBUNGAN DUKUNGAN KELURGA DENGAN KEMANDIRIAN ANAK USIA 9 TAHUN DI SD ALQODIRI JEMBE
Authors: Dita Ike Fitria Kuswarini  , Aldi Febrian Wieminaty
Published: August 2021

Latar belakang: Ketidak mandirian anak merupakan salah satu contoh kasus yang mempunyai masalah perkembangan kemandirian. Efek ketidak mandirian pada anak dapat menimbulkan kerugian pada anak yaitu anak kepribadian, kemampuan sosialisasi dan keadaan emosionalnya akan terhambat . Oleh karena itu dalam kasus ini peran dan dukungan keluarga sangatlah penting untuk meningkatkan kemandirian ada anak, agar anak bisa mandiri.

Metode: penelitian ini menggunakan metode penelitian analitik korelasi, populasi pada penelitian ini adalah anak yang berusia 9 tahun, tehnik pengambilan sampel dalam penelitian ini menggunakan random sampling, didapatkan sebanyak 45 anak.

Hasil: hasil Uji Wilcoxon, pada correlation menunjukkan nilai signifikansi ρvalue : 0,000 < 0,05 didapatkan H0 ditolak dan H1 diterima, artinya ada Hubungan Dukungan Keluarga Dengan Kemandirian Anak Usia 9 Tahun Di SDN Tisnogambar 01 Bangsalsari Jember.

Kesimpulan: dukungan keluarga sangatlah berhubungan terhadap kemandirian anak, keluarga mempunyai pengaruh yang besar untuk memupuk kemadirian anak sejak usia dini, dan dukungan keluarga berkaitan erat dengan kemandirian anak terutama pada usia 9 tahun.
Au-delà de la rhétorique : mythes et réalités du leadership et de la transformation numérique
Authors: Olcott Jr. Don
Published: August 2021

Cet article soutient que la transformation numérique et le leadership numérique sont des mythes. Le leadership numérique est une illusion et n'existe pas. Il n'y a qu'un bon leadership et un mauvais leadership... ou aucun leadership. Il est faux de penser qu'ajouter plus de technologie modifiera la qualité du leadership et conduira à une transformation organisationnelle. La transformation numérique n'est pas une question de technologie. Il s'agit de leaders visionnaires qui ont la capacité de conduire un changement systémique et d'apporter un nouveau continuum d'avantages à tous les acteurs. Ces leaders intègrent les changements dans les valeurs, la culture et l'objectif de l'organisation.  Les outils numériques ne sont qu'une des ressources qui aident les dirigeants dans cette quête. Aujourd'hui, le continuum de qualité de l'enseignement ouvert et à distance est plus fort que jamais dans l'histoire de la profession. Certes, il y a et il y aura des changements futurs dans les pédagogies, mais des pédagogies puissantes existent déjà. Nous devons simplement les dégrouper et les intégrer dans toutes les disciplines à l'aide d'outils numériques. Un leadership visionnaire qui apporte empathie et confiance pour responsabiliser et engager les étudiants, le corps enseignant et la communauté est l'outil le plus puissant dont nous disposerons à l'avenir. Les personnes, et non la technologie, sont la ressource la plus précieuse de nos organisations.
Innover, collaborer, apprendre : l’initiative École en réseau dans la mise en pratique de l’apprentissage à distance des élèves et des enseignants
Authors: Nadeau-Tremblay Sophie , Métivier Jessica
Published: August 2021

L’initiative École en réseau (ÉER) soutient des enseignants à collaborer autour de projets interclasses pour enrichir et diversifier l’environnement d’apprentissage par le numérique (Allaire et al., 2008). Les pratiques mises en œuvre ont permis de développer dans ÉER une expertise dans le travail en réseau et l’apprentissage connecté (Bruillard et al., soumis). Au printemps 2020, la situation mondiale a forcé le monde éducatif à revoir leurs manières de soutenir les élèves. La transposition de la classe en réseau, à la classe à distance fut aisée pour les enseignants d’ÉER. L’article relate l’innovation, la collaboration et l’apprentissage en réseau de cette forme pédagogique particulière mise en œuvre par ÉER pour la formation à distance des enseignants et l’enseignement à distance de l’ordre préscolaire et primaire.
Comparing the traditional and constraints-led approaches to skill acquisition in tennis
Authors: Regan Luke
Published: August 2021

The  following  article  aims to  highlight  the  differences  between  a  traditional  or  ‘information  processing’  approach  to  skill  acquisition  and  the  ‘constraints-led  approach’.  The  terms  are  defined  then  various  aspects  of  each  method  are  considered  in  the  context  of tennis  coaching.  Practical  examples   of  using  the  constraints-led  approach  are  then  given.
Development and Validation of SVPT Device for Assessing Pinch Grip Strength among Neurological Patients
Authors: Krupa Mehta , Kalpana Mair , Mair Sushrut Mair Sushrut
Published: August 2021

Aim: The purpose of this study was to develop an instrument-Smart Virtual Physical Therapist (SVPT) that assess the pinch grip strength and its measurement was recorded on a Smartphone application, and to validate Smart Virtual Physical Therapist device with standard pinchometer device.
Method: Observational study was carried out on 40 patients having neurological condition and grip affection of 20-70 years of age. Measurement of pinch grip strength was done with SVPT device and pinchometer between pulp of thumb and pulp of index finger, middle finger, ring finger and little finger. The measurement was recorded in kilogram. Measurements were done once with right hand and then with left hand.
Results: Mean values for pinch grip by SVPT device for index, middle, ring and little finger of right hand were 1.92kg, 1.74kg, 1.40kg, 1.11kg and left hand were 1.84kg, 1.71kg, 1.43kg, 1.04kg respectively. In addition to it mean values by pinchometer for index, middle, ring and little finger of right hand were 3.02kg, 2.87kg, 2.17kg, 1.61kg and left hand were 2.84kg, 2.94kg, 2.28kg, 1.62kg respectively. K value for index, middle, ring and little finger of right and left hand was 0.2. There were 25% of people who were unable to do pinch grip using pinchometer.
Conclusion: Smart Virtual Physical Therapist device can’t be replaceable with the standard baseline pinchometer to assess the grip strength. But it is a valid tool to measure pinch grip strength in neurological patients due to greater height of pressure sensor of SVPT device for pad to pad grip.

Key words: Hand, Instrumentation, Pinch strength.
Awareness, Attitude and Practices Regarding Breast Cancer Screening among Community Women
Authors: Maharjan Ratna Kumari , Panthee Bimala , Awale Shanti
Published: August 2021

Background: Breast cancer is the most common cancer among women worldwide. In Nepal, it is the second most common cancer. Early detection of breast cancer serves a leading role in the reduction of breast cancer mortality. The aim of this study was to assess the awareness, attitude and practices regarding breast cancer screening among community women
Method: A cross sectional descriptive study was carried among 316 community women. Probability simple random sampling technique was used to select the sample. Self-administered questionnaire was used to collect data. Data analysis was done by using SPSS version 16.
Result: Our results indicated that very few (7.3%) participants had good knowledge towards breast cancer screening. Half (50%) had poor attitude. Sixty two percent of participants had done breast self-examination, one fourth (25%) had done clinical breast examination and very low (10%) had done mammogram. Though very few participants demonstrated good knowledge, about 90% of participants were aware that lump in breast can be related to breast cancer and agreed that every woman is risk for breast cancer.
Conclusion: Majority of women demonstrated poor knowledge, attitude and practice towards breast cancer screening. Thus, effort should be put forth to increase the awareness of breast cancer screening for the early detection of breast cancer in the early stage.

Key words: attitude, awareness, practice, breast cancer screening, community women.
Empyema of Gall Bladder- Typhoid
Authors: Vineeth V. K. , Chandrasekaran Jagadeesh , Asokan Aarthee
Published: August 2021

Enteric fever involves reticuloendothelial system. Most common complications are intestinal perforation, hepatitis, encephalopathy and bleeding ileal ulcers. Apart from known complications we present an interesting case of middle aged female with uncontrolled diabetes presenting with empyema of gall bladder secondary to Salmonella typhi. Both blood and gallbladder tissue bacteriological cultures had Salmonella typhi confirming our diagnosis. It was noteworthy that empyema was found intraoperatively. Patient recovered after cholecystectomy and antibiotics. Considering this rare complication we advise Typhoid conjugate vaccine in tropical countries. This case report paves way to recognize this complication to watch for.

Key words: Enteric fever, Empyema, complications, Typhoid vaccine, gall bladder.
Overview of Nutritional Status in Schizophrenic Patients at Dr. Soeharto Heerdjan Grogol Hospital in 2019
Authors: . Ance
Published: August 2021

Nutritional status is a state of health due to interactions between food, the human body and the human environment. If lack of nutrients, the body will be more easily infected. Nevertheless, more nutrition can also be detrimental because it can lead to degenerative diseases. Therefore, it is crucial to maintain a balanced intake of nutrients following the body's needs. This study discusses the description of the nutritional status of schizophrenic patients at the Mental Hospital dr. Soeharto Heerdjan Grogol in 2019. This study used a descriptive observational research method to see the nutritional status and food intake of inpatient schizophrenia patients. One hundred fifty-five schizophrenia patients were hospitalized. The results showed more male patients than female patients. Changes in weight in schizophrenia patients increase more than is reduced. The most nutritional status of schizophrenia patients is good. Patients with malnutrition are 12.9%. Many patients leave <25% food. Patients with good nutrition are primarily found in the Peacock Room, which is an independent patient room.

Key words: Schizophrenia, Nutritional Status, Malnutrition, Food Intake.
Estimation of Anti-HBs Titer in Health Care Professionals of a Tertiary Care Centre of Southern Assam
Authors: Chanda Debadatta Dhar , Chakravarty Atanu , Bhattacharjee Barnamoy
Published: August 2021

Background- Due to occupational exposure to blood, body fluids and sharps, the health care professionals are at increased risk of contracting the Hepatitis B virus infection than general population. To combat this, all the health care professionals must be immunized with protective level of anti-HBs but anti-HBs titer gradually wanes with passage of time and may be influenced by gender, smoking or chewing tobacco, diabetes mellitus etc. This study was thus carried out to find the percentage of health care professionals with protective titer of anti-HBs and find the association (if any) of low anti-HBs titer and factors like gender, smoking, diabetes mellitus and time elapsed post vaccination.
Method- This cross-sectional study has been carried out with proper ethical clearance from May2018- September2019 in Serology section of VRDL under Department of Microbiology in a Medical College of Southern Assam on serum samples collected from 150 health care professionals vaccinated with 3 doses of recombinant HBsAg vaccine atleast 5years back. Anti-HBs IgG concentration was measured by conventional ELISA in multistandard mode.
Result- Out of 150 participants,95 were males and 55 were females.27 participants smoked/chewed tobacco,8 had diabetes mellitus. Booster dose was received by 23. Protective level of anti-HBs IgG (>10 IU/ml) was found in 66% (98/150) of HCP only. Low anti-HBs titer has been found to be significantly associated with Diabetes mellitus (p–0.03) and passage of more than 10 years post primary vaccination(p-0.005) but no significant association has been found with gender, smoking and history of blood transfusion.
Conclusion- HBsAg vaccine doesn’t impart everlasting protection. So, all HCP, especially those with co-morbidities should get their anti-HBs titer estimated after vaccination to check out for adequate seroconversion and attainment of protective titer. If found inadequate, they should go for repeat vaccination /booster doses.

Keywords: Healthcare professionals, Vaccinated, Anti HBs IgG, Assam,
The Application of Human Capital for Business Development in PT.Zaps Teknologi
Authors: Prima Edesico , Indradewa Rhian , Syah Tantri Yanuar Rahmat
Published: August 2021

Background - PT. Zaps Technology is a company engaged in technology and information by producing application products under the name Dokter Tunggu ( Doku ). As there are many hospital that needs to reduce their queue line. At present, PT. Zaps Teknologi has strategies in meeting human resource needs. To capture market needs, companies must have added value to their resources, especially for the expert resources. A strong HR recruitment strategy who is always able to keep up with the times is needed. Thus, this study aims to analyse the human capital strategies at PT. Zaps Teknlogi. In the implements fertility specialist selection strategies to enhance the performance of the application yet also to improve the fitures that needs by the society and environment. This is inseparable from the selection and recruitment to meet competency needs.
Method – Through the recruitment, training and development, compensation, work evaluation.
Result - This analysis help IT companies in making the right decisions to manage the human resources management

Keywords: Human Resources Management, IT Companies, Selection, Recruitment Program, Compensation, and Work Evaluation.
Implementation of Operational Strategy Planning in Doku Application
Authors: Handayani Selfi Rizky , Indradewa Rhian , Syah Tantri Yanuar Rahmat
Published: August 2021

Background - Health services are one of the most widely used public services, administered by BPJS Health reaching 222.5 million people as of December 31, 2020. This figure is equivalent to 81.3% of the total population in Indonesia. The Doku application is an application that will help level I Health Facilities and Hospitals to manage BPJS patient services. The Doku application will replace the conventional BPJS patient services at Level I Health Facilities and Hospitals to online. This business opportunity is quite large, even though there are threats from existing applications, with more brands and users, but based on the results of QSPM is product development strategy, Doku will always update features and add according to market needs.
Method - Product design operational management approach.
Result - This product design helps companies to implement user requirements in the form of user interface.

Keywords: Application, Doku, Feature Update, Business opportunity.
An Exploration on Muslim’s Motivation to Enter the Entrepreneurship
Authors: Muhamad Ali Musa , Abu Hussin Mohd Fauzi , Md Sawari Siti Salwa
Published: August 2021

To date, the number of Muslim Bumiputera entrepreneurs, primarily Malay entrepreneurs who set up their own company and engaged in various businesses were increased but their success was far from the target. Hence, the purpose of this article was to identify the motivation that encouraged Muslims to venture into business. This study was a literature study where the researcher used secondary sources from articles, theses and scientific discourses. From the results of the literature study, the researcher found that there were five main factors that motivate Muslims to venture into business which were; Worship (Ibadah), dignity, external traits, economy and unity. When Muslims are motivated to involve in entrepreneurship, they are required to prosper the natural resources with their abilities bestowed by Allah SWT. Therefore, entrepreneurs need to empower themselves with the value skills (additional value) that complement the characteristics of successful entrepreneurs. This is a starting point for the entrepreneurs who are always facing the obstacles and are always ready to compete on the global stage that requires certain skills to sharpen their competence level. This article useful empower more Muslim venture into Business.

Keywords: Muamalah, Motivation, Muslim Entrepreneurs, Economy.
Necrotizing Fasciitis: Risk Factors and Outcomes in the COVID-19 Era
Authors: Chauhan Rohit , Poddar Devadatta , Lohchab Prateek
Published: August 2021

Background: Necrotizing Fasciitis is a severe, rapidly spreading soft tissue infection with high morbidity and mortality. Diabetes mellitus, hypertension, and immune suppression are the some of the predisposing factors for the disease. The objective of this study was to study the risk factors and outcomes of necrotizing fasciitis in the COVID-19 era.
Methods and Materials: a retrospective analysis of the data of forty-four patients admitted with the diagnosis of NF from April 2020 to April 2021was done at Dr Ram Manohar Lohia Hospital, New Delhi. Data was recorded in MS Excel spreadsheet program. SPSS v23 (IBM Corp.) was used for data analysis. Descriptive statistics were elaborated in the form of means/standard deviations and medians/IQRs for continuous variables, and frequencies and percentages for categorical variables. Chi-square test (X2) was used for group comparisons of categorical data.
Results: Out of forty-four patients, 26 (59.10%) were male and 18 (40.9%) were female. The mean age was 54.2 years (+ 14.4 years). Extremities (68.2%) were the most commonly involved site followed by perineum (29.5%) and abdominal wall (2.2%). Diabetes mellitus (DM) was the most prevalent comorbidity. 10 patients had both DM and hypertension (HTN). Fourteen patients (32%) had a polymicrobial infection on tissue culture. Rest thirty patients had involvement of gram positive (44%) and gram negative (24%) organisms. Twenty-two patients (50%) had healthy granulation tissue as the final outcome. However, the rest 50% patients had a poor outcome in form of amputation (13.63%) and mortality (36.36%). Average duration from onset of symptoms to presentation at the hospital was 7.11 (+ 3.47) days. Patients who presented early to the hospital within 7 days of symptom onset had a good outcome in the form of healthy granulation tissue (X2= 7.62 and p <0.05).
Conclusions: Early diagnosis and prompt surgical intervention in necrotizing fasciitis is the key to its management. Delayed presentation was because of restricted movement, government-imposed lockdowns, patients ignoring their symptoms, and resorting to self-medications. The delay in diagnosis leading to a delay in treatment is one of the major factors contributing to poor outcomes in the COVID-19 era.

Keywords: necrotizing fasciitis, risk factors, COVID 19.
Cross Sectional Data on Profile of Coronary Artery Disease in Human Immunodeficiency Virus Infection Patients in a Tertiary Care Hospital of Central India
Authors: Rajput Atul Singh , Washimkar Sunil , Dalal Gunjan S
Published: August 2021

Background: Human immunodeficiency virus infection leads to a variety of Cardiovascular manifestations. Pericardial effusion, systemic hypertension, dilated cardiomyopathy, coronary artery disease, pulmonary hypertension, primary as well as secondary cardiac tumours etc are seen in about 30% of patients and the incidence has increased with improved longevity. Coronary artery disease ranging from subclinical atherosclerosis to coronary plaque rupture causing acute coronary syndrome have been documented. The main underlying pathophysiological process is a state of perennial inflammation which leads to initiation and acceleration of coronary atherosclerosis.
Objective: To study the coronary angiographic profile in HIV patients.
Methodology: HIV patients undergoing coronary angiography were assessed clinically, biochemically and finally by coronary angiography to see the coronary pathoanatomy.
Results: Of the 37 HIV patients studied between Jan to Dec 2019, the mean age was 47 years.(19-66 years). Two thirds were males; most common traditional risk factor was dyslipidemia followed by hypertension. Most patients were already on ART and the CD 4 counts ranged from 67-366cells/cumm. Anterior wall MI and unstable angina were the most common clinical presentations. Coronary angiography revealed diffuse disease (both insignificant and significant) of the left anterior descending artery as the most common pattern of angiographic involvement.
Conclusion: Coronary artery disease both subclinical and syndromic occurs with increased frequency in HIV patients. The dominant angiographic presentation correlates with the clinical presentation and in our study, left anterior descending artery was more frequently diseased as compared to other coronaries. The most common coronary angiographic pattern was the presence of ectasia and diffuse disease.

Keywords: Human immunodeficiency virus, cardiovascular manifestations, coronary artery disease, coronary angiography.
Местоимения vos и tú в испанском языке Монтевидео: восприятие носителей (на материале корпуса устной речи PRESEEA)
Authors: Стефанчиков Игорь Вячеславович
Published: August 2021

Представлены результаты исследования восприятия личных местоимений 2-го лица единственного числа vos и tú жителями г. Монтевидео (Уругвай). Проанализированы мнения информантов, высказанные ими в интервью из корпуса Proyecto para el estudio sociolingüístico del español de España y de América (PRESEEA). Подтверждено наличие в испанском языке Монтевидео двух параллельно функционирующих местоименных систем, а также сделано предположение о существовании третьей. Результаты могут быть использованы при дальнейшем изучении уругвайского национального варианта испанского языка (в частности, в исследованиях спонтанной речи).
Management of Gallbladder Empyema in a patient with Situs Inversus, Levocardia and Morbid Obesity: a Case Report.
Authors: Oliveira Dulcyane Ferreira de , Pinho Denis Alves , Rodrigues Fernando Fernandes , Marques Luiz Fabrício Moura , Araújo Pedro Henrique Rosa , Pinheiro Reginaldo Conrado , Rodrigues Yomara Jesuina Lins
Published: August 2021

Situs Inversus with levocardia is an unusual condition, in which the main organs of the thorax and abdomen are located in a reverse or enantiomorphic position in relation to the usual topography. It is estimated a prevalence of 1:10000 people with some Situs Inversus condition, but Situs Inversus with Levocardia is reported in only 1:22000 cases. The presence of acute cholecystitis in patients is an extremely rare event,however, one of its possible complications, Gallbladder Empyema can develop, causing an increase in severity and the need for surgical intervention. Since the inversion of abdominal organs proper to Situs Inversus with levocardia is commonly associated with the transposition of great vessels, fatally, as described in the literature of Vesicle empyema and Situs Inversus, it only occurred in patients with dextrocardia, not yet being reported in patients with Levocardia. We report a case of a female patient with pain in the left hypochondrium with Situs Inversus Viscerum, Levocardia, Empyema of Biliary Vesicles and Morbid Obesity.
The Influence of Appearance Satisfaction on Psychological Well-being and Interpersonal Relationships in College Students
Authors: Heo Eun-Seo , Son Jin-a , Kim Sun-Hyoung
Published: August 2021

This study attempted to unveil correlations among appearance satisfaction, psychological well-being, and interpersonal relationships among college students to contribute to the development of a mental health promotion program. Analysis results found the following: As satisfaction with body image and subjective appearance satisfaction increased, life's purpose also improved. In other words, with a higher appearance satisfaction, psychological well-being increased. Concerning the effects of appearance satisfaction on interpersonal relationships, as satisfaction with body image and appearance satisfaction increased, ‘satisfaction,’ ‘communication,’ and ‘intimacy’ improved, thereby forming positive interpersonal relationships. Regarding the influence of psychological well-being on interpersonal relationships, as psychological well-being improved, there was a greater possibility of maintaining a positive relationship with a good quality of life and a high level of intimacy. This study is meaningful because it confirmed that appearance satisfaction influences psychological well-being and interpersonal relationships in college students. However, this study was performed on students from a certain region only. Therefore, there should be further studies on more extensive populations.
Effect of Risk Perception on the Prevention of Beauty Salon by COVID-19 Related Customers on the Avoidance of Hair Salon and the Form of Preferred Hair Salon
Authors: Song Hye Hyun , Yang Eun Jin
Published: August 2021

The purpose of this study is to find out the impact of COVID-19 customer-oriented hair salon quarantine measures on the risk perception and preferred hair salon types, and to establish quarantine measures for each hair salon type. As a research method, self-administered questionnaire and the collected 427 were analyzed by using SPSS24.0. and structural equation modeling was performed on the result by using frequency analysis exploratory factor analysis, reliability analysis, and multiple regression analysis. As a result, the effect of preventive measures on the risk perception of visiting hair salons is that, first, spatial risk perception factors affect the definition of air quarantine, personal quarantine, and personnel control factors affect the higher the risk factor. As a result of examining the impact of hair salon quarantine measures on preferred hair salon types, first, small preference factors affect the definition of air quarantine, personnel control factors, and second, large and brand preference factors increase with higher preference for personnel control and air quarantine factors. In conclusion, through the results of this study, it is necessary to prepare improvements to various hair salon quarantine measures to reduce the risk of customers entering Hair Salon and to ensure smooth inflow of each salon.
PM 10 Exposure Induced IL-1β and IL-6 Expression in Hairless Mouse Skin
Authors: Kim Min Kyung , Kim Jeong-hee
Published: August 2021

More recently, air pollution is acknowledged as an immense risk factor for developing serious health issues, and particulate matter (PM10) are a common air pollutant. To evaluate the biological mechanisms of PM10 on skin damage. PM10 was applied to mouse skin at 10 µg/mL for 7 days. In this study, we analyzed that PM10-induced inflammation on hairless mouse skin by immunohistochemistry and western blot. As a result, immunohistochemical staining demonstrated that the IL-1β and IL-6 expression levels were increased after PM10 treatment. Moreover, the analysis of western blot suggested that PM10 treatment increased the expression levels of proinflammatory cytokines IL-1β (**P<0.01) and IL-6 (**P<0.05). In conclusion, our findings contribute to the understanding of the pathophysiological mechanisms of PM10 to the skin and can be used as a therapeutic strategy to control inflammatory skin diseases caused by PM10.
A Study on the Effect of Perceived Trust and Value of Hair Beauty O2O Service of Women Customer's on Customer Acceptance Intention and Satisfaction
Authors: Kwon Eun-Sil , Lim Yoon-Kyeong , Pack Eun-Jun
Published: August 2021

This study was to clarify the effects of perceived trust and value of hair beauty O2O service of women customer's on customer acceptance intention and satisfaction. Based on the result, the purpose of this study is to suggest the effective marketing strategy of O2O service for customers. As for the subject of this study, 240 women customers who used O2O services in Seoul, Kyonggi and Chungcheong Province were selected to respond to and analyzed the self-administered questionnaire. Collected data was analyzed using SPSS 22.0. Analytical analysis was carried out on the data in the form of frequency analysis, factor analysis, reliability analysis and regression analysis. The results of this study are summarized as follows. In the demographic characteristics shown in the results of the study, thirties of Seoul and Kyonggi Province were the highest. Married in marital status, students and specialized job in occupation, less than 2 million won in average monthly income and vocational colleges attendance or graduation in the highest level of education turned out to be the highest. Second, the result of the effect of perceived trust of hair beauty O2O service on customer acceptance intention and satisfaction are as follows. Acceptance intention and satisfaction were found to have significant result in trust of product, trust of information and trust of O2O. The effect of trust of information on acceptance intention and satisfaction was the highest. Third, he result of the effect of perceived value of hair beauty O2O service on customer acceptance intention and satisfaction are as follows. Acceptance intention and satisfaction were found to have significant result in functional value, psychic value. The effect of psychic value on acceptance intention and satisfaction was the highest.
Study on Efficacy Evaluation of Deramal Bioactive Properties of the Prunus tomentosa Fruits Fermented with Lactobacillus acidphilus
Authors: Jung Da-Bin , Choi Hwa-Jung , Yun Mi-Young
Published: August 2021

The materials fermented with natural products have been used in a variety of cosmetic applications as a whitening, wrinkle and inflammatory agent. Prunus tomentosa fruits have been used as a traditional medicine for anti-oxidant and have been reported to possess anti-microbial properties. This study investigated the deramal bioactive properties of the Prunus tomentosa fruits fermented with Lactobacillus acidphilus (PTF). The antioxidant activity of the PTF was measured by 1,1-diphenyl-2-picryl hydrazyl (DPPH) method. The cytotoxicity of human dermal fibroblast cell, murine macrophage cell line RAW 264.7 and B16-F10 melanoma cells were evaluated by sulforhodamine B (SRB) assay. Inhibitory effect of the PTF on nitric oxide (NO) prodction was evaluated by Griess Reagent System. The collagen synthesis was evaluated by using procollagen type-IC peptide (PIP) EIA kit. The tyrosinase activity, inhibitory effect of elastase and tumor necrosis factor-α (TNF-α) induced matrixmelloproteinase-1 (MMP-1) were also evaluated. It found that the PTF showed antioxidant activity without showing significant cytotoxicity in tested cells. The PTF were downregulated NO production in LPS-stimulated macrophages with nocytotoxicity (p<0.05). The PTF significantly induced collagen synthesis from the skin fibroblasts (p<0.05) and also dramatically inhibited MMP-1 activity (p<0.05). The PTF were inhibited activity of elastase and dramatically decreased melanin synthesis with inhibition of tyrosinase activity (p<0.05) and didn’t show cytotoxicity in B16-F10 melanoma cells. Therefore, the PTF showed bioactive properties on anti-oxidant, whitening, skin elasticity and anti-wrinkle efficacy. The PTF may be an appropriate choice for cosmetic products that aim to provide dermal bioactive effects.
Awareness regarding Antibiotic Stewardship among nurses at selected hospitals, Chennai
Authors: Sudhakar Manju , Dhakshinamoorthy Sasikala
Published: August 2021

Background: Antibiotics are medicines that fight bacterial infections. They can save lives if they are used correctly, but nowadays antibiotic resistance has become a real problem.1 Infections by resistant microorganisms do not respond treatment, which prolongs the hospital stay, and increases the risk of death. Moreover, if the treatment fails or if the response to treatment is slow, the patient is contagious for longer, which increases the likelihood of transmission of resistant microorganisms.2 The clinical outcome can be improved with optimization of antibiotic practices. The aim of the study was to assess the level of awareness regarding Antibiotic stewardship among nurses. Methods andMaterials: A cross sectional descriptive correlational research design was adopted to assess the awareness of nurses on antibiotic stewardship. An extensive review of literature and guidance from the experts formed the foundation to the development of the tools such as demographic variables proforma, MCQ questionnaire on antibiotic stewardship in google form. The present study was conducted in selected tertiary care center at Chennai, among 60 nurses selected by purposive sampling technique. After obtaining setting permission and research participants’ consent, a brief introduction of the research was given. Then the data were collected using the predetermined tools through email using google forms. The collected data were organized and analyzed using descriptive and inferential statistics. Results: More than half of nurses had adequate overall knowledge on antibiotic stewardship (55%), majority of them had adequate knowledge in antibiotic treatment (60%) and nurses’ responsibility (63.33%). Around half of them had adequate knowledge in drug related side effects (46.67%) and its causative agents (50%). Conclusion: The present study reveals the necessity for continuous nursing education for knowledge update regarding importance of nurses regarding antibiotic stewardship.
Remodeling in the Prefrontal Cortex of a Brain-related to Higher Executive
Functions in Adolescence: Its effects on Behavior
Authors: Moe Nwe Tin , San Aye San , Than Yee Khi , Lwin Soe , Bhagat Vidya
Published: August 2021

Adolescence is a critical stage of the developmental trajectory, where a child’s transition to independent living
may result in healthy or unhealthy styles. During this period, it is easier to mend an individual as a healthy adult;
at the same time, misguided children may enter into risky behaviors. The aim of the study to get an insight into
changing brains of adolescents and their behavioral outcomes. The current review search engine proceeds with
reviewing the literature in the past through electronic databases such as PubMed, Medline, and Scopus databases
using keywords such as adolescent stage, the brain of teenagers, risk behaviors, reduction in gray matter in the
prefrontal cortex. The current study reviewed and analyzed 20 articles. The reviewed articles would increase the
awareness and insights regarding brain changes and their behavioral outcomes. This insightful information’s
drawn out of the study may help professionals and parents who intervene the adolescent’s problem behaviors.
Zakres i efekty restrukturyzacji a kreacja wartości przedsiębiorstw produkcyjnych
Authors: Kaczmarek Jarosław
Published: August 2021

Ocena działań restrukturyzacyjnych może być rozpatrywana w zależności od charakteru uzyskanych efektów, skuteczności, rozległości ich wpływu czy stopnia szczegółowości. Jednym z jej wymiarów jest weryfikacja kreowania wartości, będącej kwantyfikowalnym wymiarem rozwoju przedsiębiorstwa i miarą jego efektywności. Ocenę efektów restrukturyzacji (przedmiot badań) przedsiębiorstw produkcyjnych (podmiot badań – ponad 16 tys.) przeprowadzono w artykule w czterech wiodących obszarach zmian, tj.: kosztochłonności przychodów ze sprzedaży, produktywności majątku, struktury majątkowo-kapitałowej oraz odnawiania zasobów majątku trwałego. Pomiaru kreacji wartości dokonano przy użyciu miar względnych – stopy zwrotu z kapitału własnego i stopy wartości dodanej. Oceny tych procesów (ich współwystępowanie) dokonano dla długiego szeregu czasowego (lata 1990–2014).
Aktywa niematerialne – fundament rozwoju podkarpackich przedsiębiorstw
Authors: Dziura Bernadetta
Published: August 2021

W gospodarce opartej na wiedzy rośnie rola aktywów niematerialnych w kreowaniu wartości przedsiębiorstwa. Jego źródłem są zasoby niematerialne, których główny składnik stanowi kapitał ludzki. Odpowiednie zarządzanie kapitałem intelektualnym zmusza przedsiębiorstwa do inteligentnego działania, którego celem jest stosowanie innowacji, ciągła praca zatrudnionych pracowników oparta na wiedzy o wysokiej jakości, jak również podejmowanie twórczych i odważnych decyzji. Wyniki analiz z przeprowadzonych badań dowodzą, iż kapitał intelektualny, który jest w posiadaniu firm, wpływa na rozwój oraz kondycję finansową. Pomimo wykorzystywania tego potencjału intelektualnego do realizacji celów przedsiębiorstw, menedżerowie powinni jeszcze skuteczniej nim zarządzać. Celem artykułu jest pokazanie, że rozwój firm – ze szczególnym uwzględnieniem przedsiębiorstw działających w województwie podkarpackim, wynika z wysokiego poziomu aktywów niematerialnych, który jest w posiadaniu podkarpackich firm.
Possibility to recover vat in a journey as a determinant of the shopping tourism
Authors: Paliś Beata , Śliwińska Irena
Published: August 2021

The aim of the article is to examine whether VAT recovery has a chance to become a factor encouraging tourists to travel for shopping purposes. The article presents theoretical issues regarding shopping tourism and its determinants as well as the results of own research. The following research methods were used: literature review, legal acts analysis and survey conducted in January 2019 on a group of 124 Polish consumers of tourist services. This study showed low awareness of the consumers regarding the possibility of VAT recovery, which is the biggest barrier in using tax free system. To increase number of tourists using this system, promotion activities on a local level should be conducted.
Rearing white leg shrimp larvae (Litopenaeus vannamei Boone, 1931) with concentrated diatom (Thalassiosira sp.)
Authors: Tran Nhien V.
Published: August 2021

The objective of the experiment was to determine the best type of algae for growth, survival rate and the metamorphosis time of white leg shrimp larvae. The experiment consisted of five treatments: dried Spirulina sp. (NT 1), fresh Chaetoceros sp. (NT 2), fresh Thalassiosira sp. (NT 3), Thalassiosira sp. in concentrated form (NT 4) and Thalasiosira sp. in paste form (NT 5). The larvae at Nauplius VI were stocked in 0.5 m3 tank at the stocking density of 200 inds/L. The care regime was applied according to the popular process at the National Breeding Center for Southern Marine Aquaculture. After 10 days of stocking, the water parameters in all treatments were in a suitable range for the growth of larvae. The larvae in NT 4 showed the best body length, survival rate, metamorphosis time and were significant difference compared to the remaining treatments (P < 0.05). Whereas NT 5 was not significantly different (P > 0.05) compared to NT 2 in body length and NT 3 in metamorphosis time. NT 1 showed the worst these characteristics to the other treatments. In general, the use of concentrated Thalassiosira sp. for rearing white leg shrimp larvae gives good results, which should be commonly applied.
The fallacy of the water "sector" in water resources management
Authors: Herron Colin
Published: August 2021

Water resources are central to the achievement of all the Sustainable Development Goals, and should be viewed as a crosscutting connector - not a sector. The water community should do more to get outside its safety zone and work with all water-related sectors. The SDG 6 IWRM Support Programme is assisting countries to use water as a connector between their SDG targets.
Pesquisa, Pânico e Pandemia
Authors: Fernandes Gabriel Marques
Published: August 2021

Em 2020 teve início o Mestrado Acadêmico em História Social do Programa de Pós-Graduação em História do Instituto de História da Universidade Federal de Uberlândia (PPGHI/INHIS/UFU), tendo como um dos objetivos do ano letivo a realização, pelos discentes, do Estado Atual da Arte; porém, em Março, o Brasil enfrentou uma condição extraordinária: a Pandemia de COVID-19. Devido ao isolamento social, arquivos e bibliotecas fecharam. Considerando que as atividades de pesquisa não poderiam parar: é possível realiza-las, inteiramente, exclusivamente, através da internet? Este artigo responderá essa questão, abordando os temas da superprodução, digitalização e dos mecanismos de busca (destacando o Google Acadêmico), concluindo que: sim, é possível pesquisar em tempos pandêmicos; porém, “novos” espaços, “novos” problemas.
COVID-19
Authors: Stinieski Mariana Silveira
Published: August 2021

Este artigo buscou contextualizar e refletir sobre os impactos sociais no Brasil, pela pandemia promovida pelo Covid-19 e se estes se tornaram um trauma social. Observou-se que as autoridades, especialistas e a população divergiam em relação aos cuidados sanitários, medidas protetivas sociais e tratamento dos acometidos pela doença. Além da repetição de comportamentos diante de epidemias e pandemias passadas, como na febre amarela e na gripe espanhola. Para isso, buscou-se, a partir de um viés psicanalítico, identificar o que poderia estar por trás dessas atitudes. Pelo Brasil estar vivenciando a pandemia, não é possível trazer conclusões sobre o possível trauma social, mas é importante observar de que forma a sociedade tem se comportado, considerando o momento cultural que preza o individualismo, a satisfação narcísica e as fantasias do sujeito que cada vez estimulam menos o viver coletivo.
O jornalismo científico e as pandemias no contexto brasileiro
Authors: Lopes Pablo De Oliveira
Published: August 2021

Os primeiros casos da Síndrome da Imunodeficiência Adquirida (SIDA, em espanhol, ou AIDS, na sigla em inglês) foram documentados, em junho de 1981, no Estados Unidos. A imprensa não pôde manter-se indiferente à enfermidade, já que ela se tornou uma pandemia. Em dia 31 de dezembro de 2019, na cidade de Wuhan, na China, informou-se sobre os primeiros relatos de pneumonia causada por um novo coronavírus, o SARS-CoV-2, denominada Covid-19, em referência ao tipo de vírus (do inglês, Coronavirus disease) e ao ano de início da epidemia (2019). O presente trabalho analisará como duas epidemias, a AIDS e a Covid-19, chegaram à imprensa brasileira, e serão discutidas semelhanças entre as coberturas jornalísticas de ambas.
Emotional Intelligence and Perceived Stress in Medical Education: A Questionnaire Based Survey among Medical studens
Authors: Fatima Nimra , Abid Saliha , Ullah M. Saad , Aziz Mian S , Saleem M. Nasir , Raja Hina Zafar , Dar Daniyal Naeem , Tariq Amina
Published: August 2021

Aim: To investigate the levels of EI and perceived stress (PS) among two groups of healthcare students (medical and dental) and examined their relationship. Methods: A cross-sectional questionnaire survey was conducted among medical and dental undergraduates and interns at CMH Lahore Medical College and Institute of Dentistry to assess their levels of EI and PS. Participants were assessed on self-administered Sterrett’s EI questionnaire and Perceived Stress Scale (PSS). The data col-lected from 627 participants was analyzed using SPSS version 24. Results: Correlational analysis showed an inverse relationship between EI and PS among medical and dental un-dergraduates. Significant association was observed between level of EI and year of study for both the disciplines. Majority of the participants reported moderate levels of EI and PS. Conclusion: EI can positively affect the students’ ability to perform well under stressful situations in healthcare education. Undergraduate curriculum should be designed to focus on EI based education in order to enable healthcare students to cope well with the stress related to their clinical training. Keywords: Emotional Intelligence, stress, medical education, medicine, dentistry
Evaluation of job Satisfaction among Freshly Graduated Doctors and Dentists
Authors: Hassan Arooj Ul , Jasmin Rabia , Asghar Fadia , Hannan Abdul , Rehm Hassam , Hassan Muhammad , Tariq Amina
Published: August 2021

Aim: To evaluate job satisfaction among junior graduated Doctors and Dentists. Methodology: A cross sectional survey was conducted from three Medical and Dental colleges. At the time of study, there were a total of 50 Dentists and 50 Doctors. A pre-validated questionnaire was used for data collection consisted of 20 questions, the content of the questionnaire included socio-demographic characteristics and lists of factors for job satisfaction and dissatisfaction. Data was entered and analyzed using SPSS version 20. Frequencies and Percentages were calculated as descriptive statistics whereas independent sample t-test was conducted as inferential statistics. Results: The results of independent sample t test revealed that significant difference regarding job satisfaction was found among freshly graduated Doctors and Dentists in terms of Fringe Benefits (t=2.82, P=.006), Working with Coworkers (t=-2.314, P=.023) and Nature of Work (t= -2.375, P=.020). Conclusion: In terms of fringe benefits, Doctors were more satisfied as compared to dentists. In terms of coworkers and nature of work, Dentists were more satisfied as compared to Doctors. In all other categories there was no significant difference Keywords: Freshly Graduate, Job Satisfaction, Dentists, Doctors
Kırsal Alanlarda Koruma Sorunları: Bursa Cumalıkızık Köyü Örneği
Authors: AKTÜRK İbrahim
Published: August 2021

Geleneksel yaşamın ve yöresel sanatın göstergesi olan kırsal alanların tarihi, kültürel ve mimari değerleriyle korunması gereklidir. Kırsal mirasın gelecek kuşaklara aktarılması için öncelikli olarak koruma sorunlarının teşhisi yapılmalıdır. Sorunların tespitine dayalı olarak rehabilitasyon çalışmaları planlanmalıdır. Bu doğrultuda kırsal alanlarda geleneksel mimarlık ürünlerinin özgün dokusuyla korunup yerel halkıyla yaşaması sağlanmalıdır. Sorunların temelinde kırsal yerleşimlerin bakımsızlığı ve terk süreci oldukça etkilidir. Kırsal kalkınma, kırsal sürdürülebilirlik ve kırsal turizm konuları araştırılarak çalışmanın önemi vurgulanmıştır. Çalışmanın devamında koruma sorunlarına ilişkin bilgiler verilerek literatür taraması yapılmıştır. Koruma sorunları kırsal alanlarda genel başlıklar halinde toplumsal, ekonomik, mimari ve yasal sorunlar olarak ortaya koyulmuştur. Bu bağlamda çalışmanın esas kısmını oluşturan Bursa Cumalıkızık köyü ve çevresi çalışma alanı olarak seçilmiştir. Ardından çalışma alanında gözlemlenen kırsal mimariye ilişkin koruma sorunları problem olarak belirlenmiştir. Koruma sorunları belirlenirken alan çalışması ve alanda yapılan tespitler etkili olmuştur. Cumalıkızık köyü özelinde koruma sorunlarının temelinde mimari sorunlar öne çıkmaktadır. Ekonomik sıkıntılarla birleşen sorunlar alanın fiziki yapısında bozulmaları ve eskimeyi artırmaktadır. Çalışmanın sonuç kısmında alana ilişkin koruma sorunlarına yönelik değerlendirmeler yapılarak öneriler verilmiştir. Ortaya koyulan önerilerin kırsal alana olan katkıları ve başka kırsal yerleşimlere örnek teşkil etmesi bakımından önemli olmaktadır.