bluuebunny/crossref_metadata_2025 huggingface dataset:
Impacts of wetland loss and fragmentation on the hydrology of Zimbabwe's highveld
Authors: Magure Martin , Gumindoga Webster , Makurira Hodson , Rwasoka Donald Tendai
Published: November 2022

Wetland loss and fragmentation are among the greatest threats to water resources in developed and developing countries. While several studies on wetland fragmentation have been done, a few have looked at impacts of wetland fragmentation on hydrology, with none having been done on Zimbabwe's highveld headwater catchments. There is a critical need to investigate the influence of wetlands on flow regimes of highveld headwater catchments, to understand the hydrological role that wetlands play in sustaining water resources. Endowed with dambos, marshes and riverine wetlands, Zimbabwe's highveld play a significant role in sustaining Zimbabwe's water resources, with major river systems originating from the highveld plateau, having wetlands as their source regions. Hydrologic impacts of wetland fragmentation on flow regimes of highveld headwater catchments i.e., Upper Manyame (Manyame catchment), Nyagui (Mazowe catchment) and Macheke (Save catchment) were analyzed for the period from 1984–2021. Analysis of landcover and wetland change as well as streamflow characteristics was done for 1984, 1994, 2004, 2014 and 2021 periods. Simulation of streamflow under wetland fragmentation was done using the topographically driven rainfall-runoff model (TOPMODEL), which was set up, calibrated and validated for the most sensitive parameters, which include scaling parameter (m), transmissivity (To) and root zone available water capacity (SRmax). Results from landuse/cover analysis for the period between 1984 and 2021 showed a decrease in wetland area, followed by an increase in built up area and bare land for the same period, owing to expansion of urban areas and cultivation into wetland areas. Hydrological simulation by TOPMODEL and flow duration curve analysis show that wetland fragmentation has resulted in increased peak flows, while low flows have declined for the three catchments. The findings of this research would be helpful in understanding the hydrological functions of highveld wetlands, providing the reference for protection and sustainable utilization of wetland resources in the highveld catchments.
Investigations on the co-occurrence of microplastics and other pollutants in the River Yamuna, Delhi
Authors: Vaid Mansi , Mehra Komal , Sarma Kiranmay , Gupta Anshu
Published: November 2022

The Yamuna River is a threatened resource of freshwater in Delhi, India. The present study is focused on investigating three important contaminants, namely microplastics (MPs), heavy metals, and fecal coliforms in the surface water of the river, with major emphasis on MPs occurrence and characterization. MPs showed an increase in abundance in the river from the Wazirabad barrage (n = 500 MPs/m3) to the Okhla barrage downstream (n = 3,900 MPs/m3) in Delhi, with a maximum abundance downstream to the Najafgarh and Shahdara drain outfalls. White color and fragmented shape were prevalent characteristics of the isolated MPs. Attenuated total reflectance–Fourier transform infrared (ATR-FTIR) spectroscopy revealed five types of polymers. Heavy metals (chromium, lead, manganese, and iron) and fecal coliforms were at unacceptable levels at most of the sampling sites. Due to the emergence of issues concerning the tendency of MPs to actively interact with heavy metals and pathogenic microorganisms, investigation of the co-occurrence of such harmful pollutants is very important. The present study is aimed at this issue and urges similar kinds of investigations in other riverine regions of our country, as well as globally, due to their scarcity in literature. This study can further provide a baseline database to help the Government of India's efforts to clean and revive the Delhi stretch of the Yamuna River.
Circulação infanto-juvenil
Authors: Temoteo Francisca , Dias Layra Nobre , Pólvora Jacqueline Britto
Published: November 2022

O presente artigo tem como ponto de partida a análise das dinâmicas internas na comunidade da Estrada Velha em Acarape – CE, que culminou na observação da circulação infanto-juvenil. Gerando curiosidade sobre esse tema e sobre seus atores, o que fazem e quais os motivos da população infanto-juvenil circularem por diversos ambientes, entre casas e ruas, becos e famílias em uma comunidade interiorana do maciço de Baturité . O objetivo deste estudo é entender o que é a circulação, como se dá e o que gera esse fenômeno na comunidade. Nesse sentido, no decorrer da escrita, apontamos os motivos desse afastamento e as situações em que as dinâmicas entre as mulheres influência no circular das crianças. A metodologia utilizada trata-se de uma pesquisa descritiva e qualitativa com a ferramenta da observação participante em campo, que possibilitou observar, dialogar e analisar as condições que envolvem a circulação.
FATORES DESENCADEANTES PARA LIMITAÇÕES SOCIAIS E SAÚDE MENTAL EM DIABÉTICOS
Authors: Soares Albenize de Azevêdo , Araújo Astha Oliveira Catônio de , Souza Talita Araujo de , Silva Jose Adailton da
Published: November 2022

Introdução: A Diabetes Mellitus é caracterizada como uma síndrome de múltiplas etiologias, que ocorre pela falta de insulina, ou resistência do organismo à mesma, estando relacionada à diversas complicações que demandam ao paciente adaptações no modo de viver e que podem ser geradores de sofrimento psicológico. Objetivo: Identificar os principais fatores desencadeantes para a ocorrência de limitações sociais e suas consequências na saúde mental de pacientes convivendo com diabetes. Metodologia: O estudo configura-se como revisão integrativa da literatura. Utilizou-se como critérios de inclusão: artigos completos, publicados de 2015 a 2020, nos idiomas inglês, português e espanhol. Foram excluídos: documentos de editoriais, revisões, resenhas, capítulos de livros e artigos que não atendessem ao objetivo proposto. A busca dos estudos se deu entre os meses de outubro a novembro de 2020 nas bases de dados: Medline (via PubMed®), Cumulative Index to Nursing and Allied Health (CINAHL) e Excerpta Medica DataBASE (EMBASE). Foram utilizados descritores controlados identificados nos Descritores em Ciência da Saúde (DECs), Medical Subject Headings (MESH) e EMBASE Emtree, resultando em 2.063 estudos na identificação, passando por triagem e permanecendo 718, após a elegibilidade resultou em 12, dando origem a 9 estudos na amostra final. Resultados: A amostra final resultou na criação de eixos temáticos que trazem o aumento do sofrimento psicológico em pessoas com diabetes ocasionados pelas mudanças no estilo de vida, na falta de apoio familiar e social, na inatividade física, no impacto do gênero e da cultura, e no aumento dos sintomas de complicações e de comprometimento funcional, sendo desencadeantes para a ocorrência de limitações sociais. Conclusões: A diabetes e o seu tratamento geram limitações sociais na vida dos pacientes, pela necessidade de mudanças no estilo de vida que demandam muita dedicação e tempo, tais fatores são considerados preditores para o aumento dos riscos de sofrimento psicológico nesses pacientes.
USO DE ANTICORPOS MONOCLONAIS POR PACIENTES COM COVID-19 INTERFERE NA CONCENTRAÇÃO SÉRICA DE ANGIOTENSINA II?
Authors: Fernandes Paiva Daniel Felipe
Published: November 2022

Introdução: uma vez conhecidos os mecanismos de patogênese do Sars-Cov-2, vários métodos de tratamento para a COVID-19 foram desenvolvidos, dentre eles destaca-se o uso dos anticorpos monoclonais para o contexto de pacientes em estágios graves da doença. Objetivo: compreender se o uso dos anticorpos monoclonais para tratamento da COVID-19 grave interfere nos níveis séricos da angiotensina II. Metodologia: Para a realização dessa pesquisa foram selecionados através do DeCS e MeSH os descritores “COVID-19”, “Angiotensin II” e “Antibodies, Monoclonal” e seus respectivos “entry terms” sugeridos pela base MeSH. Posteriormente,utilizando-se os operadores booleanos OR e AND, foi montada uma estratégia de busca,  a qual foi utilizada nas bases de dados PUBMED, EMBASE, Web of Science, Cochrane Library e Scopus, sem restrição de data de publicação ou idioma. Resultados: ao final do processo de seleção dos artigos, 29 foram selecionados para a leitura e análise completa. Nesta revisão, foram abordados diferentes tipos de anticorpos monoclonais, os quais foram oportunamente agrupados de acordo com o seu mecanismo de ação. Conclusão: foi possível concluir que das cinco classes de anticorpos monoclonais tratadas neste trabalho, três potencialmente podem causar alterações nos níveis séricos de angiotensina II.
PERFIL EPIDEMIOLÓGICO DOS PACIENTES HOSPITALIZADOS COM COVID-19 NO MUNICÍPIO DE MOSSORÓ-RN
Authors: Gomes Farias Ariadne , Araújo Cunegundes de Brito Andiara , Do Vale e Silva Jennifer , Taborda Ribas da Cunha Andrea , Maciel de Queiroz Janaina , Oliveira Reis de Freitas Kalidyjamayra , Elizabeth Lopez Carrillo Sonia , Miyoshi Sakamoto Sidnei , De Moraes Maiara
Published: November 2022

Introdução: Assim como observado no cenário nacional, o município de Mossoró apresentou altas taxas de letalidade nos primeiros meses de pandemia. Todavia, o conhecimento epidemiológico em torno da Covid-19 no município tem ocorrido, sobretudo, através de documentos institucionais das Secretarias de Saúde. Desse modo, a finalidade deste estudo é fornecer evidências que permitam ampliar a compreensão da ocorrência da doença em nível local, ofertar dados e informações que venham a subsidiar as políticas públicas de saúde municipais e gerar hipóteses sobre a morbimortalidade da doença para futuras investigações científicas. Objetivo: Analisar o perfil epidemiológico dos casos internados e confirmados de Covid-19 no município de Mossoró no estado do Rio Grande do Norte/Brasil. Metodologia: Estudo observacional transversal, baseado em dados secundários de casos internados de Covid-19 registrados no Sistema Único de Saúde entre março e outubro de 2020. Resultados: Foram incluídos na amostra 664 pacientes, dos quais 46,5% evoluíram para óbito. Entre as internações, 63,1% resultaram em internações em unidades de terapia intensiva (UTI). Observamos diferenças estatísticas significativas entre 'admissão na UTI e evolução para óbito' e 'faixa etária e evolução para óbito' e, maior risco entre idosos acima de 60 anos, com comorbidades, dispneia e saturação de O2 <95%. A necessidade de suporte ventilatório invasivo foi considerada fator predisponente para óbito. O risco de internação na UTI foi maior entre as idosas. Conclusões: A hospitalização e o óbito de pacientes com COVID-19 foram maiores em pacientes idosos com comorbidades.

Palavras-Chave: COVID-19; infecção por coronavírus; Epidemiologia; pandemia; Brasil.
PERDA DENTÁRIA E SUAS CONSEQUÊNCIAS PSICOSSOCIAIS EM ADULTOS E IDOSOS
Authors: Andrade Bruno Vidal , Carvalho Fábio Silva de , Alves Paz de Carvalho Cristiane
Published: November 2022

Introdução: É notório que a perda dentária é um obstáculo a ser lidado na saúde bucal, sendo ainda considerado um problema de saúde pública no Brasil que gera consequências físicas e psicológicas principalmente para adultos e idosos. Objetivo: Descrever as principais consequências psicossociais ocasionadas pela perda dentária em adultos e idosos. Metodologia: Trata-se de uma revisão integrativa da literatura, em que foram realizadas buscas bibliográficas eletrônicas com intervalo de tempo de publicação de seis anos (2016 - 2022) nas bases de dados Biblioteca Virtual em Saúde (BVS) e Scientific Electronic Library Online (SciELO). Foram usados os descritores Perda de Dente, Saúde Bucal, Impacto Psicossocial, Adulto e Idoso com o auxílio do operador booleano “and”, sendo contemplados artigos em português e inglês no qual o título, o resumo e a leitura na íntegra se relacionassem com o tema, e excluídas publicações do tipo monografias, dissertações, teses, capítulos de livros, livros na íntegra e artigos que não abordaram o tema de estudo. Resultados: Foram utilizados 14 artigos no total para compor o referencial teórico da revisão, sendo que todas essas publicações trouxeram informações relevantes quando se associa a perda dentária com o impacto psicossocial no público alvo. Conclusão: A perda dentária abala a qualidade de vida das pessoas. Fatores psicológicos como a timidez, a vergonha e alteração de rotinas influenciam na vida social de adultos e idosos.

Palavras-Chave: Perda de Dente; Saúde Bucal; Impacto Psicossocial; Adulto; Idoso.
Uso de insecticidas biorracionales para el manejo de plagas de insectos de almacenamiento: Una revisión
Authors: Parajuli Sovit , Adhikari Aavash , Paudel Sandip , Oli Dipesh , Bhandari Sagar , Shrestha Jiban
Published: November 2022

Las plagas de varias especies causan estragos en los granos almacenados, lo que resulta en pérdidas de granos tanto cualitativas como cuantitativas. Las plagas de insectos alimentan los granos almacenados y reducen el peso, el contenido nutricional y la germinación de estos granos. La contaminación, el olor, el moho y el daño por calor también son causados por infestaciones, lo que disminuye la calidad del grano y lo vuelve inadecuado para el consumo humano o animal. Los compradores comerciales de granos pueden elegir entre negarse a aceptar granos infestados de insectos o pagar un precio reducido por ellos. Se han probado varias prácticas de manejo de plagas. La aparición de resistencia a insecticidas y fungicidas, así como el daño a organismos no objetivo y los efectos agudos y crónicos en humanos y el medio ambiente han requerido el uso de métodos biorracionales sobre el control químico de plagas de productos almacenados. El término biorracional se refiere a varios productos que son relativamente no tóxicos y tienen pocos efectos ambientales adversos. Las técnicas biorracionales, como el uso de microbios, feromonas y atrayentes alimentarios, enemigos naturales, productos botánicos y control biológico, se utilizaron como alternativas a los plaguicidas químicos para suprimir y controlar las plagas de productos almacenados. Para garantizar la seguridad alimentaria y la sostenibilidad agrícola, el uso de estos productos químicos biorracionales es inevitable.
Estimate Final Cost of Roads Using Support Vector Machine
Authors: Hasan Musaab Falih , Hammody Oday , Albayati Khaldoon Satea
Published: November 2022

Introduction:

The cost overrun in road construction projects in Iraq is one of the major problems that face the construction of new roads.

Method:

To enable the concerned government agencies to predict the final cost of roads, the objective this paper suggested is to develop an early cost estimating model for road projects using a support vector machine based on (43) sets of bills of quantity collected in Baghdad city in Iraq. As cost estimates are required at the early stages of a project, consideration was given to the fact that the input data for the support vector machine model could be easily extracted from sketches or the project's scope definition.

Result:

The data were collected from contracts awarded by the Mayoralty of Baghdad for completed projects between 2010-2013. Mathematical equations were constructed using the Support Vector Machine Algorithm (SMO) technique.

Conclusion

An average of accuracy (AA) (99.65%) and coefficient of determination (R2) (97.63%) for the model were achieved by the created prediction equations.
Research on Shrinkage and Shrinkage Models of Reinforced Concrete Specimens
Authors: Zhang Guilin , Chen Pang , Si Xiaoyu , Wang Jingde , Han Yang
Published: November 2022

Introduction:

It is very important to accurately predict the shrinkage of reinforced concrete specimens to ensure structural safety.

Methods:

In this study, a total of 36 reinforced concrete specimens were used with a size of 150mm×150mm×450mm to examine concrete strength grades and longitudinal reinforcement ratios on the shrinkage of reinforced concrete specimens using shrinkage tests.

Results:

The results showed that the concrete strength increased from 35MPa to 58.2MPa, and the shrinkage rate of concrete decreased by about 30%. The ratio of reinforcement increased from 0 to 2.01%, and the shrinkage rate of concrete decreased by about 40%.

Conclusion:

The experimental results were compared with existing shrinkage models of reinforced concrete, and a modified shrinkage calculation model of reinforced concrete was proposed.
Interaction of Lysosomes and Calpain on Neurofilament Steady-state Levels
Authors: Vohnoutka Rishel Brenna , Myre Michael , Sargent Ava , Shea Thomas B.
Published: November 2022

Background:

An imbalance of protease activity can foster the aberrant accumulation of phosphorylated neurofilaments (NF) within perikarya resembling human neuropathological conditions.

Objective:

We examined whether or not the inhibition of the lysosomal system increased NF levels.

Method: Differentiated NB2a/d1 cells were transfected with GFP-tagged NF-heavy and treated with chlorquine (active against autophagy) and/or a calpain inhibitor. Additional cells were transfected with the cyclin-dependent kinase 5 activator p35.

Results:

Unexpectedly, chloroquine decreased NF levels, which was prevented by the simultaneous treatment with the calpain inhibitor or expression of p35.

Discussion:

These findings suggest that compensatory increases in calpain activity can accompany inhibition of autophagy. This reduction was also prevented by the expression of the cdk5 activator p35, consistent with the resistance of extensively phosphorylated NF-H to proteolysis by calpain.

Conclusion:

These findings highlight the complex interplay among kinase, phosphatase, and protease systems in neuropathology.
Effect of Folic Acid Conjugated Silver Nanoparticles in Treatment of RA Like Adjuvant Arthritis in Rats
Authors: Ahmed Hajar K. , Elbeialy Adel A. , Mansour Ahmed M. , El-Zomor Hala M. , Abosaif Amany I.
Published: November 2022

Objective:

Nano medicine has become one of the promising research areas, opening new horizons in disease diagnosis and treatment. Recent years have witnessed a surge in the development of Nano medicine for combating rheumatoid arthritis (RA), the most common autoimmune arthritis. RA is characterized by progressive inflammation and persistent synovitis, leading to joint destruction, functional incapability, and ultimately disability. Although there has been a tremendous evolution in disease assessment and treatment, many patients still fail to attain remission. Therefore, developing new drugs that specifically target inflamed joints and simultaneously attenuate other possible damages to healthy tissues is indispensable. This study was done to evaluate the potential of folic acid conjugated silver nanoparticles (FA-AgNPs) as RA therapy.

Methods:

In the CFA-arthritic rat model, FA-AgNPs & methotrexate were administered for 8 consecutive weeks. Therapeutic efficacy was evaluated by measuring paw volume, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), tumor necrosis factor (TNF-α), and interleukin-6 (IL-6) levels. For safety concerns, complete blood picture (CBC), liver and renal function tests were evaluated. Joints histological assessment was also carried out.

Results:

FA-AgNPs significantly reduced paw volume, paw weight, ESR, CRP, RF, TNF-α, and IL-6 levels compared with arthritic non-treated rats, demonstrating good anti-inflammatory activity. Likewise, histology of tarsal joints depicted comparatively lesser inflammatory cellular infiltration and diminished cartilage erosions. Methotrexate displayed comparable results. In contrast to methotrexate, FA-AgNPs showed normal CBC & significantly improved liver and renal function tests.

Conclusion:

FA-AgNPs exhibited substantial anti-arthritic activity. This notable anti-arthritic potential of FA-AgNPs was as good as the current standard treatment of methotrexate (MTX) with higher biosafety.
The Pattern of Pediatric Acute Respiratory Distress Syndrome over 10 Years Period and Related Risk Factors of its Outcome Mortality
Authors: Albuali Waleed H. , Alghamdi Amal
Published: November 2022

Background:

Although paediatric acute respiratory distress syndrome (PARDS) is a common and devastating clinical syndrome that contributes to high morbidity and mortality, there is little known about its pattern and outcome mortality over time.

Objective:

This study aimed to determine the pattern of PARDS over a 10-year period and the risk factors for its outcome, mortality.

Methods:

This study was done at King Fahd University Hospital in Saudi Arabia using a retrospective study design involving children aged from > 2 weeks to 14 years admitted to the PICU due to PARDS. Over the last ten years, data was extracted from their medical records.

Results:

The number of PICU admissions over the last ten years was 2317, the rate of PARDS amongst PICU admissions was 376/2317 (16.23%), and mortality amongst PARDS cases was 83/376 (22.07%). ER admission route, chronic liver disease, sepsis, fluid overload, the number of inotropes 3, and pneumonia mediastinum were significant predictors of mortality in PARDS (p 0.001). In addition, the mean PRISM III score, PICU admission days, and ventilation days were higher in the deceased than in the survivors of PARDS. In contrast, the mean PaO2/FIO2 and oxygen saturation indices were significantly lower among the deceased than the survivors (p 0.01).

Conclusion:

Although the rate of PARDS was alarming, the number of PARDS deaths was constant over the study period. Sepsis, ER admission route, comorbidities, fluid overload, a higher PRISM III score, longer PICU admission, and ventilation days increased the risk of PARDS mortality.
Differences in Bone Mineral Density Values in Postmenopausal Women with Fracture and Non-Fracture
Authors: Suryana Bagus Putu Putra , Tarigan Ricky Cornelius , C J Huwae Thomas Erwin
Published: November 2022

Background: Osteoporosis is an increasing health problem in Indonesia. Fractures that occur in the spine and pelvis are considered to be the most common fracture sites for osteoporosis.
Aim: to determine the differences in bone mineral density values in postmenopausal women with fracture and non-fracture.
Methods:  Survey was carried out in postmenopausal female patients with fractures and without fractures who were included in the inclusion criteria with a case-control study approach and had bone mass density data. For the group of cases with fracture, the amount of vertebral compression was measured using Gennant's measurement criteria. Interviews were conducted regarding the characteristics of patients with and without fracture. The differences in BMD values ​​were analyzed in postmenpausal female patients with fracture and without fracture by using unpaired T test on normal data distribution and Mann-Whitney test on abnormal data distribution. The measured BMD value is the T-score. The analysis result was considered significant if p <0.05.
Results: There was a significant difference between L4 BMD (p = 0.029) and femoral neck BMD (p = 0.014) in postmenopausal female patients with fracture and without fracture. However, there were no significant differences for other BMD regions (p> 0.5).
Conclusion:  BMD L4 and femoral neck values ​​differ significantly in female patients with postmenopausal osteopenia with fracture and non-fracture.
Diagnosis and Management of Cognitive Dysfunction In Systemic Lupus Erythematosus Patients
Authors: Rahman Perdana Aditya , Mahardini Ernes , Wahono Cessarius Singgih , Kalim Handono
Published: November 2022

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with diverse clinical manifestations. One of the frequent manifestations of SLE is cognitive dysfunction. Cognitive dysfunction is a hidden and often undiagnosed manifestation of SLE but can severely impair quality of life even in mild cognitive dysfunction. Early detection of cognitive dysfunction in SLE patients can determine interventions to help patients adapt to the effects of this decline in cognitive function. However, currently, screening and diagnosis of cognitive dysfunction in SLE are often delayed, and monitoring cannot be done properly. This may be due to the most appropriate assessment tool for cognitive screening in SLE patients has not been agreed upon. The management of cognitive dysfunction in SLE patients today is still challenging due to the SLE pathophysiology is still in debate and research. This literature review will discuss the approach of diagnosis and management of cognitive dysfunction in SLE.
Transaminase Level of Severity and Mortality of COVID-19 Patients at RSUD Dr. Saiful Anwar Malang
Authors: Fiqih Faruz  , Supriono Supriono , Pratomo Bogi , Mustika Syifa
Published: November 2022

Background: Extend of lung injury, inflammation due to SARS COV-2 can also cause liver injury. Liver injury in COVID-19 patients can be caused by the direct effect on the liver, cholangiocyte role, activation of the immune system, drug-induced liver injury, and hypoxic injury. Hepatocyte necrosis could increase the transaminase. Therefore, transaminase increase may reveal the inflammation severity.
Aim: This study aims to know the relationship of transaminase to the severity and mortality of COVID-19 patients.
Method: A retrospective study of 177 COVID-19 patients hospitalized at Saiful Anwar Hospital Malang. The data were taken from the medical record of COVID-19 patients. The level of transaminase was taken on admission. The severity criteria of COVID-19 were taken from the Indonesian COVID-19 Guidelines. Chi-Square Test and Pearson Correlation Test were used as the statistical analysis with a significance of 0.05 (p=0.05) and a confidence interval of 95% (CI=95%).
Results: From the correlation test, the AST had R=0.42 (p < 0.001) for severity and R=0.17 (p < 0.001) for mortality. The ALT had R=0.33 (p < 0.001) of severity and R=0.28 (p < 0.001) of mortality.
Conclusion: There was a significant relationship between AST and ALT in the severity and mortality.
Treatment Challenge in COVID-19 Patients with Acute Kidney Injury in Hospital
Authors: Pratama Mirza Zaka , Rifa'i Achmad , Sianturi Duma
Published: November 2022

Renal, the main characteristic of COVID-19 infection. Acute kidney injury (AKI) has been documented in 20-50% of the hospitalized COVID-19 patients. Renal involvement among COVID-19 patients might be multifactorial. COVID-19 Patients with AKI significantly had higher mortality than patients without AKI. This case series reported severe COVID-19 with respiratory failure and AKI during admission to the hospital. All patients were admitted to the intensive care unit (ICU) and obtained the standard therapeutic protocols according to the COVID-19 severities. The first patient developed AKI in the three days of admission, while the second and third patients had AKI from the first day of admission. The patients had similar complications, including type 1 or 2 respiratory failures, secondary infection with sepsis, hyperpotassemia, and metabolic acidosis. The first and second patients underwent hemodialysis as indicated on these patients. However, the evaluation of their renal functions did not improve after that. The third patient did not receive the hemodialysis therapy and only obtained supportive treatment with adequate fluid therapy. The third patient was getting better on the 16th day of admission. In addition, the renal function test was getting normal after the 16th day of admission. The patient was discharged on the 19th day of admission in stable condition. Early recognition of renal involvement in COVID-19 infection, preventive measures, renal function monitoring, and therapeutic intervention were essential to reduce the morbidity and mortality of COVID-19 patients. Hospitalized patients should be monitored closely for their renal function to prevent renal function deterioration in the future.
Veinzen of verlangen? Spel en geloof bij Johan Huizinga en Frans Kellendonk
Authors: Kuil R.W.N.
Published: November 2022

Historian and linguist Johan Huizinga’s theory of the function of play in human culture in Homo ludens (1938) includes a discussion of the close link between liturgy and play. In the 1980’s author and cultural critic Frans Kellendonk put forward the notion of sincerelyfeigning (‘oprecht veinzen’) in relation to faith in a post-Christian society. This article examines the socio-cultural background of Huizinga’s and Kellendonk’s ideas and their personal commitment to the faith. It concludes with a consideration of the question: Towhat extent can sincerely feigning be considered a sign of longing?
Explotación de recursos naturales y delitos financieros
Authors: Jiménez Diaz Pablo Emilio
Published: November 2022

Colombia es un país rico en recursos naturales, pero a causa del surgimiento de estructuras criminales y la prevalencia de la corrupción, pareciera estar condenado a sufrirlos como una maldición, pues desde hace más de cuarenta años los señores de la guerra los explotan para enriquecerse o financiar sus acciones contra el Estado. Esto deja a Colombia como uno de los países con más conflictos medioambientales por resolver en el mundo, en especial aquellos relacionados con la minería ilícita, la deforestación y los cultivos de drogas, los cuales generan una economía paralela que supera con mucho el presupuesto de la mayoría de ministerios y departamentos como el Chocó y el Cauca. En este capítulo se busca esclarecer cómo funciona la cadena de producción ilícita que financia a dichas estructuras criminales.
Oportunidades para el desarrollo sostenible y reflexiones finales
Authors: Jiménez Diaz Pablo Emilio
Published: November 2022

Colombia es un país muy rico en recursos naturales que pareciera estar condenado a sufrir las consecuencias de la maldición de tenerlos. Sin embargo, como se verá en este capítulo, hay acciones que pueden desarrollarse para mejorar la situación, que no dependen únicamente del gobernante de turno, sino de las instituciones que tratan de controlar las amenazas medioambientales, tales como el Ejército Nacional de Colombia. Esto sin duda significa un gran avance en el proceso de recuperación y estabilización de las condiciones sociales del país que abre caminos a la construcción de la paz y el desarrollo sostenible. Para ello se hacen indispensables dos acciones: por una parte, fomentar la unidad política, de modo que la sociedad tenga un objetivo común pese a las diferencias y aprenda a emplear la cooperación como mecanismo para alcanzar metas de desarrollo, y, por otra, que el Gobierno cree las condiciones para generar innovación y optimizar la competitividad.
COMPARISONS OF TOURIST CIRCUIT PATTERN AT SELECTED TOURISM DESTINATION IN SABAH, MALAYSIA
Authors: Pirdaus Yusoh Mohamad , Dering Nabila Farysha , Mapjabil Jabil , Abdul Latip Normah , Kumalah Mohd Jirey , Hanafi Nurhazliyana
Published: November 2022

The tourist circuit pattern is one of the factors that are influenced by tourists' willingness to pay for a vacation at a tourist destination. As such, this article will examine the relationship between tourist space and willingness to pay in Kundasang - Ranau and Kota Belud, Sabah. The assessment and case study methods were used in the research. The study used quantitative methodologies, including a questionnaire survey of 150 respondents who visited selected tourist locations in Kundasang-Ranau and 93 respondents who visited Kota Belud. The survey's findings indicated that the majority of respondents (87.3% - Kundasang, Ranau) and (61.3%- Kota Belud) who visited the two study locations traveled privately and prioritized destinations they had never visited while selecting tourist destinations. The majority of respondents (70%) in Kundasang - Ranau agreed that the fee rate charged has an effect on the direction of their journey. In Kundasang - Ranau, the respondent's roaming space is dictated by the tourism package, and the tourist attraction visited by the respondent is nearby, whereas in Kota Belud, the opposite is true. Following that, the bulk of respondents who arrived at Kota Belud were determined by their roaming space in accordance with the institution or organization's determination. The study's findings also revealed that the majority of respondents who visited the two study areas did so on their own and that the tourist destinations visited were relatively near together.
SUSTAINABLE SPATIAL SETTINGS OF KUALA KUBU BHARU
Authors: Misni Alamah , Basir Ahmadi Khan
Published: November 2022

Cultural heritage landscapes present historical and cultural civilization signs and legacies in their environment. These landscapes are also considered necessary incentives to attract tourists. Cultural heritage conservation provides tools for reaching suitable solutions for sustainable development based on tourism. Subsequently, the significance of societal identity and way of life in the past was crucial to explaining the current cultural and social dynamic. Determining the value of heritage is especially important to plan the form of its protection, conservation, and contemporary use. The study aimed to assess and evaluate cultural heritage landscape conservation in sustainable spatial settings. This study used qualitative methods by field measurement/survey interview and site observation. The findings revealed that the cultural heritage landscape value presents historical and cultural civilization signs and legacies in the environment and landscape of the sustainable spatial setting of Kuala Kubu Bharu. This study hopes to help local authorities and related agencies restructure baseline data in planning for sustainable spatial settings and appropriately develop and maintain their historical values and natural ecosystem.
Effects of Cooling and Magnesium Supplementation on the Objective and Subjective Outcomes of Acute High-Intensity Rowing
Authors: Li Shu-Ting , Jang Jia-Tzer , Koller Ákos
Published: November 2022

Background: Body temperature and level of magnesium in the body can be important factors affecting the level of exercise activities. However, beneficial effects of body cooling and magnesium supplementation on acute high-intensity exercises have not yet been studied in large number of athletes. We hypothesized that cooling interventions and supplementation of magnesium will improve both objective and subjective outcomes of acute high-intensity exercises. Subjects and Methods: Twenty-four athletes with different backgrounds of sports were recruited (n = 24, all males; age 25 ± 4 years; weight 76 ± 10 kg; height 175 ± 5 cm). Indoor rowing was used as acute high-intensity exercise. Subjects were evenly and independently assigned to four groups, namely, (1) Group C: control group, (2) Group HC: hand cooling intervention (HC), (3) Group WBC: whole-body cryotherapy intervention, and (4) Group MgS: magnesium supplementation. Each group had three measurements: before exercise, during acute high-intensity 1000 m open-end rowing, and in the recovery period. During rowing, the power output and speed values were collected at every 200 m. Before and after rowing, the following six parameters were collected; objective outcomes: ammonia (NH3) and lactate (La) of blood plasma, heart rate (HR), whole-body temperature (TW), and subjective outcome: rate of perceived exertion (RPE) by standard questionnaire, and self-rated perception of thermal sensation (TS). Results: HC, MgS and WBC (which significantly lowered TW as compared to other groups (p < 0.05), but it did not elicit significant changes in the measured parameters (such as La, NH3, HR, RPE, rowing power, and rowing speed). In terms of TS, as the subjective outcome, we observed positive effects in response to all three interventions of HC, WBC, and MgS compared to Group C. We also observed a slight, yet significant difference of the RPE between interventions of HC and WBC. Conclusions: Data show that whole-body cryotherapy lowers body temperature and together with magnesium supplementation – without affecting objective outcomes - improve the thermal sensation. Thus, we propose that cooling intervention and magnesium supplementation - in certain conditions - can enhance output of acute high-intensity exercise, especially in warm environment. Abbreviations: HC - hand cooling; WBC - whole-body cryotherapy; La - lactate; NH3 - blood ammonia; HR - heart rate; TS - thermal sensation; RPE - rate of perceived exertion; TW - whole-body temperature
Psychometric Properties of the Chinese Warwick-Edinburgh Mental Well-being Scale in Medical Staff: Cross-sectional Study
Authors: Dong Aishu , Huang Jing , Lin Shudan , Zhu Jianing , Zhou Haitao , Jin Qianqian , Zhao Wei , Zhu Lianlian , Guo Wenjian
Published: November 2022

Background

Worldwide, mental well-being is a critical issue for public health, especially among medical staff; it affects professionalism, efficiency, quality of care delivery, and overall quality of life. Nevertheless, assessing mental well-being is a complex problem.

Objective

This study aimed to evaluate the psychometric properties of the Chinese-language version of the 14-item Warwick-Edinburgh Mental Well-being Scale (WEMWBS) in medical staff recruited mainly from 6 hospitals in China and provide a reliable measurement of positive mental well-being.

Methods

A cross-sectional online survey was conducted of medical staff from 15 provinces in China from May 15 to July 15, 2020. Confirmatory factor analysis (CFA) was conducted to test the structure of the Chinese WEMWBS. The Spearman correlations of the Chinese WEMWBS with the 5-item World Health Organization Well-Being Index (WHO-5) were used to evaluate convergent validity. The Cronbach α and split-half reliability (λ) represented internal consistency. A graded response model was adopted for an item response theory (IRT) analysis. We report discrimination, difficulty, item characteristic curves (ICCs), and item information curves (IICs). ICCs and IICs were used to estimate reliability and validity based on the IRT analysis.

Results

A total of 572 participants from 15 provinces in China finished the Chinese WEMWBS. The CFA showed that the 1D model was satisfactory and internal consistency reliability was excellent, with α=.965 and λ=0.947, while the item-scale correlation coefficients ranged from r=0.727 to r=0.900. The correlation coefficient between the Chinese WEMWBS and the WHO-5 was significant, at r=0.746. The average variance extraction value was 0.656, and the composite reliability value was 0.964, with good aggregation validity. The discrimination of the Chinese WEMWBS items ranged from 2.026 to 5.098. The ICCs illustrated that the orders of the category thresholds for the 14 items were satisfactory.

Conclusions

The Chinese WEMWBS showed good psychometric properties and can measure well-being in medical staff.
Social Media for Public Health: Framework for Social Media–Based Public Health Campaigns
Authors: de Vere Hunt Isabella , Linos Eleni
Published: November 2022

The pervasiveness of social media is irrefutable, with 72% of adults reporting using at least one social media platform and an average daily usage of 2 hours. Social media has been shown to influence health-related behaviors, and it offers a powerful tool through which we can rapidly reach large segments of the population with tailored health messaging. However, despite increasing interest in using social media for dissemination of public health messaging and research exploring the dangers of misinformation on social media, the specifics of how public health practitioners can effectively use social media for health promotion are not well described.
In this viewpoint, we propose a novel framework with the following 5 key principles to guide the use of social media for public health campaigns: (1) tailoring messages and targeting them to specific populations—this may include targeting messages to specific populations based on age, sex, or language spoken; interests; or geotargeting messages at state, city, or zip code level; (2) including members of the target population in message development—messages should be designed with and approved by members of the community they are designed to reach, to ensure cultural sensitivity and trust-building; (3) identifying and addressing misinformation—public health practitioners can directly address misinformation through myth-busting messages, in which false claims are highlighted and explained and accurate information reiterated; (4) leveraging information sharing—when designing messages for social media, it is crucial to consider their “shareability,” and consider partnering with social media influencers who are trusted messengers among their online followers; and (5) evaluating impact by measuring real-world outcomes, for example measuring foot traffic data.
Leveraging social media to deliver public health campaigns enables us to capitalize on sophisticated for-profit advertising techniques to disseminate tailored messaging directly to communities that need it most, with a precision far beyond the reaches of conventional mass media. We call for the Centers for Disease Control and Prevention as well as state and local public health agencies to continue to optimize and rigorously evaluate the use of social media for health promotion.
ГОЛОГРАФИЧЕСКИЙ НАНОДЛИНОМЕР
Authors: Турухано Б.Г. , Турухано И.А. , Лавров Ю.М. , Ермоленко О.Г. , Ханов С.Н.
Published: November 2022

В этой статье авторы освещают современное состояние измерительной техники, в частности при измерении линейных размеров объектов вертикальными нанодлиномерами голографическими (НДГ) на базе голографических дифракционных решеток.
ЭЛЕКТРОННАЯ СТРУКТУРА ВАРИАНТОВ СКАНДАТНЫХ КАТОДОВ
Authors: Капустин В.И. , Ли И.П. , Шуманов А.В.
Published: November 2022

Методами электронной спектроскопии для химического анализа (ЭСХА) и спектроскопии характеристических потерь энергии электронов (СХПЭЭ) исследована электронная структура кристаллитов оксида бария, легированного другими химическими элементами, в том числе скандием из скандий-содержащих фаз. Сформулированы физические и физико-химические условия, выполнение которых позволяет сформировать электронную структуру скандатного катода с высоким уровнем термоэлектронной эмиссии.
Crisis, funcionalidad y tipología familiar en pacientes con cáncer de mama
Authors: Soto-Araujo Pamela , Salazar-Orozco Fernanda , Ramírez-Leyva Diego H. , Valle-Iribe Canek , Medina-Serrano Julio M. , Flores-Lujano Janet
Published: November 2022

Objetivo: describir la crisis, funcionalidad y tipología familiar en pacientes con cáncer de mama. Métodos: estudio transversal analítico, se realizó entre agosto y diciembre de 2021. La muestra fue de 250 pacientes con cáncer de mama que cumplieron los criterios de selección. La presencia de crisis familiares se determinó con el test de Holmes-Rahe. La funcionalidad familiar se valoró con la Escala de Evaluación de Adaptabilidad y Cohesión Familiar iii. La tipología familiar se determinó con base en su conformación. Realizamos estadística descriptiva e inferencial. Para el análisis bivariado se utilizó razón de momios, χ2  de Pearson y U de Mann-Whitney con intervalos de confianza de 95% (p<0.05). Resultados: la frecuencia de crisis en pacientes con cáncer de mama fue de 89% (enfermedad personal, cambios en los hábitos de sueño, alimentación y condiciones familiares), las familias disfuncionales se presentaron en 58% y la tipología familiar más frecuente fue nuclear (63%). Conclusión: un alto porcentaje de pacientes con cáncer de mama tienen crisis familiares, las cuales se generaron durante el proceso de la enfermedad.
Analysis of Medical Specialists Graduated in Mexico from 2012 to 2018. National Study
Authors: Heinze Gerhard , Guízar-Sánchez Diana , Bernard-Fuentes Napoleón
Published: November 2022

Objective: to analyze the educational quality of graduates through the following academic indicators: a. Occupational mobility, b. Number and type of scientific publications, c. Publication of chapters or medical literature, d. Postgraduate studies, and e. Certification by the corresponding specialty board. Method: descriptive cross-sectional study. Different databases were reviewed, the following stand out: 1. List of graduates. 2. Registry of the different specialties; National Regulatory Committee of Medical Specialties Councils to know both the certification status, and in the General Management of Professions, belonging to the Ministry of Public Education, the professional certificate status. 3. Index of journal authors (PubMed, Embase, Medline), 4. Databases of medical insurance and health institutions in Mexico and 5. Databases of Postgraduate Degrees in Medicine Results: The academic indicators of 14,770 medical specialists who graduated from the Sub-direction of Medical Specialties of the unam in the last six years were analyzed. The trajectory of the graduates shows a gradual increase in the percentage of board certifications, number of published articles, and postgraduate courses. Nearly 60% of the specialists work in Mexico’s three largest cities. Conclusion: the number of graduated specialists is insufficient in quantity and distribution to cover the health needs of the country. Despite the increase in scientific production, there is still a need to increase the number of research projects, and scientific publications by graduates. It is necessary to rethink medical specialty programs in accordance with health care needs, and the international context.
Pautas a seguir para publicar en la revista Atención Familiar
Authors: Dávila-Mendoza Rocío , López-Ortiz Geovani
Published: November 2022

En diversas instituciones dedicadas a la preparación académica de médicos generales y especialistas no existen cursos formales de redacción científica, esto propicia desconocimiento al respecto de los elementos comunes que deben cubrir los diferentes tipos de artículos médicos e imposibilita el desarrollo de habilidades y destrezas necesarias para difundir conocimiento. Dado este contexto, el objetivo de este escrito es proporcionar pautas para publicar diversos tipos de artículos en la revista Atención Familiar, su seguimiento y adhesión permitirá a los autores incrementar la posibilidad de que sus manuscritos sean aceptados.
¿Por qué me afecta los ojos la diabetes mellitus?
Authors: Estrada-Alvarado Martha B. , Galicia-Hernández Nancy , García-Hernández Ana K. , Rivero-López Carlos
Published: November 2022

Comunicación con el paciente
Fractura tipo III de Salter- Harris en radio distal
Authors: Domínguez-Gasca Luis Gerardo , Salazar-Horner Diana Laura , Domínguez-Carrillo Luis Gerardo
Published: November 2022

Identifique el caso
Clinical Evaluation of ‘Punarnava Amrita Guggulu’ in the Management of Vata-Rakta (Gout)
Authors: Charan Dr. Divya , Mishra Dr. Pramod Kumar , Sharma Dr. Indu
Published: November 2022

Abstract: An unusual metabolic condition is Vata-Rakta. The chronic relapsing and intermittent nature of Vata-Rakta illness makes it extremely distressing. The overall prevalence of hyperuricemia is 25.8%, with a larger percentage of men than women having increased serum uric acid. Vatarakta is the name for the illness that is characterised by Raktadhatu aberration brought on by Vata Dosha morbidity. At the current study, Punarnava Amrita Guggulu was taken twice daily with lukewarm water in doses of 1gm (two 500mg tablets each). Results revealed that Vidaha (Burning sensation) (58.33%), Sandhi Shoola (reduced by 65.71%), Sandhi Shotha (reduced by 54.76%) were all statistically very significant outcomes of the current study. Raga (Redness in joints) (60.71%), Toda (Pricking sensation) (57.95%) and Twakvaivarnya (Discoloration) (61.25%). Sparsha Asahyata (Tenderness in joints) (52.47%) Visphota(58.60%) Sandhi Akunchana Prasarana Vedna(63.49%) Sandhi Vikriti (Deformity Status) (47.14%).
Analysis of SNMP Based Protocols in IoT and Real- World Scenarios
Authors: R Gautam , P Suyog , Nagaraja G S
Published: November 2022

bstract: In the scenario of large organizations device management and maintenance plays an important role in proper functioning of network connected devices. SNMP (Simple NetworkManagement Protocol) is an internet Protocol running in the application layer of the OSI modelthat governs the functioning of the network devices such as routers, switches and access points. The implementation of SNMP is done mainly using UDP (User Datagram Protocol) which is best effort protocol leaving the responsibility of error correction to the application layer. Whatcan be gathered from the local device and what may be modified and set are specified by SNMPManagement Information Bases, or MIBs for short.