bluuebunny/crossref_metadata_2025 huggingface dataset:
University of Winnipeg
Authors: Harvey Carol
Published: March 2021

The University of Winnipeg is a bustling campus situated in Winnipeg’s downtown. Within the space of one city block, some eight thousand students pursue degrees, diplomas and certificate programs in the Humanities, Social Sciences, Sciences, and Education. Most courses lead to the three or four-year B.A. or B.Sc. or the four-year Honours degree; the five-year integrated B.Ed./B.A. or B.Sc. program combining academic and professional courses is increasingly popular. Master’s programs are offered by the Faculty of Theology and a small number of Joint Master’s programs is available in conjunction with the University’s sister institution, the University of Manitoba. Although there is no department of Medieval Studies as such or an interdisciplinary program, several departments do offer courses that introduce undergraduate students to the field.
University of Manitoba
Authors: Portnoy Phyliss
Published: March 2021

The state of medieval studies at the University of Manitoba can be easily deduced from the length of this description. Alternatively, the small scale of our contribution to die discipline is readable in the recent statistics of my department:
University of Guelph
Authors: Ewan Elizabeth
Published: March 2021

The study of the medieval world has declined considerably in the last decade at the University of Guelph. Medieval studies has traditionally been discipline-based rather than interdisciplinary here; as a result the low priority accorded to the medieval period in various departments meant that retirements or departures by faculty during the 1990’s led to the loss of most medievalists at the university.
Trent University
Authors: Keefer Sarah Larratt
Published: March 2021

The study of medievalism at Trent University, increasingly popular judged by student registration over the past decade, has just taken a new and exponential step forward with the approval by its Undergraduate Academic Development Committee of an Emphasis in Medieval and Renaissance Studies (M.A.R.S.), to begin in the Fall of 2003. Trent’s M.A.R.S. Emphasis is under the aegis of the Medieval Academy of America: Committee on Centers and Regional Associations (CARA), and is open to all students eligible for any Joint or Single Honours program of study in Arts or Science at Trent.
University of Ottawa
Authors: Merkley Paul
Published: March 2021

At the University of Ottawa we have a multidisciplinary undergraduate (concentration) program in Medieval Studies housed within the Faculty of Aits. Most of the students take it as a second concentration, most frequently with history, literature, or classics. When we took stock of the program in 1994, it was barely alive, with an enrolment that had been consistently under ten students and no attention given to the program in matters of curriculum or publicity for more than a decade. This situation was not surprising, since all of the university's resources and administrative attention flow through departments and our medieval studies program received only what came its way occasionally and incidentally.
Medieval Literature at McGill
Authors: Bray Dorothy
Published: March 2021

The Department of English at McGill University has recently lost two of its medievalists, one to early retirement and one to another institution (a decision made largely for personal reasons), and for several years has had no specialist in medieval drama. The Department now has only two full-time medievalists, with the result that its offerings in medieval literature have fallen off somewhat. A few years ago, the Department also made the effort to change all its courses to 3-credits. The 6-credit introductory course in Old English thereby fell away, as did student interest. However, we have managed to keep an Old English course going at the upper level, and a new, 300-level, 3-credit Introduction to Old English is being offered next year, in the hopes of being able to offer both the introductory course in Old English and the upper-level course as a follow-up. The Department over the past few years has maintained its offerings in Chaucer, as well as in other medieval topics (gender, religion, folklore, Arthurian tradition, and literary theory); this year we were able to put on Chaucer at both the undergraduate and graduate level, an Old English undergraduate course, and two upper-level undergraduate courses in Middle English literature (on allegory and on romance). We have approval to advertise for a position in Late Medieval/Early Renaissance, which we hope we will be able to fill next year. The Department now has a very strong Renaissance studies component (especially in Shakespeare), and we are hoping to boost our medieval offerings by creating a bridge with the Renaissance.
University of New Brunswick
Authors: Klinck Anne
Published: March 2021

Medieval studies are not one of the areas that the University of New Brunswick emphasises. It is only in the English Department that they are substantially taught, and the department does not require eidier Old or Middle English for the doctorate. We do have three medievalists: an Anglo-Saxonist (myself) and two middle English specialists—Christa Canitz at the Fredericton campus and Janies Noble at Saint John. It is likely that Old English will disappear from our offerings when I retire in five years.
English 380: Literature in Translation: Medieval Jewish Literature; Studies in medieval culture
Authors: Delany Sheila
Published: March 2021

Jewish culture has a continuous existence of nearly three millennia. This course isolates a small portion of it to read, in translation, work composed during the Middle Ages by authors from several countries and in several genres: parable and fantasy, lyric and lament, polemic, marriage manual, romance. Some of our material has not been translated into English before and is not yet available in print. We are fortunate to have brand-new pre-print copies of Meir of Norwich and especially of the famous Yiddish romance the Bovo-buch (in the course-pack)—an early modern version of a widely-read (non-Jewish) medieval text. Primary texts will be supplemented by scholarly books on which each student will offer a short class presentation.
Editorial Postlude
Authors: Toswell M.J.
Published: March 2021

In my youth I enjoyed the job of church organist in a small Anglican church in northern Ontario. At the time (when I started I was thirteen and an impetuous soul), I found it unjust that I was entrusted with the role of ending the Sunday service, since it was my sole decision when to start playing the postlude. Having, so-to-say, ended the service first, I was nonetheless always the very last person out the door. Mine was the job, many a Sunday, of locking the church, because the minister was away to the next obligation, the deacon had counted and double-checked the take, the Altar Guild had polished and replenished, and the choir (my sidekicks) had cleverly got out first. It was, however, understood that having a postlude, and a post-postlude, and a spot of extra practice since I was there, provided a pleasant backdrop to the rest of the ecclesiastical business. I played on.
Lay Women in the Hospitals of Late Medieval Bergamo
Authors: Cossar Roisin
Published: March 2021

Throughout Italian cities in the later Middle Ages, civic and ecclesiastical authorities consolidated small hospitals primarily designed to house the sick, poor, and other social marginals into large institutions with a mandate to provide professional medical care to the entire community. In many cities in northern Italy, hospital restructuring was accompanied by the establishment of provveditori di sanità - guardians of public health - to oversee the medical profession and prevent outbreaks of plague. These changes were preceded by several decades of reform measures designed to bring hospitals more effectively under the control of civic and ecclesiastical authorities. Traditionally, historians have presented this period of reform as the triumph of Renaissance rationality over defective, corrupt medieval institutions. Examining hospital reform through the lens of gender complicates that view by revealing that the reform of medieval hospitals was accompanied by ambivalence among authorities towards the activities of lay women who had previously lived undisturbed within the institutions. Tracing the reasons for changes to perceptions of women in hospitals forces us to redefine the effects of hospital reform at the end of the Middle Ages.
Dating an Early Dominican Missal
Authors: Pope Joseph
Published: March 2021

The Bergendal Collection of mediaeval manuscripts took its inspiration and inception in the nineteen-seventies at the Pontifical Institute of Mediaeval Studies in Toronto. Its guiding light from the beginning was the late Father Leonard E. Boyle, O.P., who taught at the Institute from 1961 to 1984. The author was a student of Father Boyle, and profited from his love for and extraordinary expertise in all things mediaeval, especially in the manuscript sciences of palaeography and diplomatics. In 1984 the present Holy Father Pope John Paul II appointed Father Boyle as Prefect of the Vatican Library. The catalogue of the Bergendal Collection was published just before Father Boyle’s death in Rome in 1999. The Collection that he inspired and that grew under his direction is the largest to be found in private hands in the Americas. That many of its manuscripts originated in the mediaeval Order of Friars Preachers is no coincidence, since Father Boyle was himself a priest of the Dominican Order. There is no similar private collection in Canada nor in the United States of America. There are three or possibly four larger private collections in Europe.
Reflections on a Foxy Trick
Authors: Burrell Margaret
Published: March 2021

Why does the unnamed lady in Jean Renart’s Lai de I ’ombre finally submit to the blandishments of the knight and grant him her love? She has, after all, already sent him firmly on his way until she sees that he has slipped his ring on her finger and is obliged to summon him back. Does his ruse of then throwing the offending ring into the well justify her capitulation?
Reflections of the Book of Job and Gregory’s Moralia in Chaucer’s “Monk’s Tale”
Authors: Wurtele Douglas
Published: March 2021

In one of the crucial scenes in James Joyce’s A Portrait of the Artist as a Young Man an appalled Stephen Dedalus is listening to the Lenten homily on the pains of hell that await unrepentant sinners. The Jesuit preacher is implicitly echoing the same despairing outcries from Righteous Job about the darkness of hell that Chaucer’s Pilgrim-Parson explicitly recalled on the road to Canterbury some five centuries before. The two preachers have the same purpose: to arouse so overwhelming a sense of contrition in the sinner that heartfelt repentance and unrestrained confession will pour out. Both are also well aware of the central place occupied in the Office of the Dead by lectiones from the Book of Job. As Lawrence Besserman explains, Job became "the principal biblical figure in the fully developed Office of the Dead of the High Middle Ages," and the text of the office in use at Salisbury Cathedral, the so-called Sarum Use, well known of course to Chaucer, "had gained wide acceptance and had what amounted to official recognition from Rome.".
Value Chain Analysis of Maliputo, Caranx ignobilis in the Philippines
Authors: Muyot Myla C. , Balunan Rielyn L. , Muyot Frederick B.
Published: March 2021

Maliputo (Caranx ignobilis) is a high-value food fish in the Philippines with limited studies on market potential. This value chain analysis study was conducted to understand the industry, to identify the key actors, supply and value chain, and to identify issues and concerns to support the development of C. ignobilis industry. A survey interview was conducted using purposive sampling in nine maliputo-producing regions with 224 respondents, and focus group discussion validated the analyzed data. Key chain actors identified are fishers, fish cage operators, fish buyers categorized as small-scale (local vendors and peddlers) and large-scale intermediaries (commission agents and wholesalers), and processors (restaurants and resorts). Annual production was 188,722 kg valued at PHP 33,752,859.79 with 58.12% coming from capture fisheries and 41.88% from aquaculture. Major producing regions for captured and cultured C. ignobilis are Regions 2 (Cagayan), 6 (Iloilo), and 3 (Central Luzon). The industry’s value chain map showed a gross value addition of PHP 116.58, 135.65, 75.04, 23.58, and 749.71 per kg maliputo for capture, aquaculture, small-scale fish buyer, large-scale fish buyer, and processors, respectively. Processors attained the highest net returns while fishers got the lowest. This study noted that C. ignobilis is a non-target species in capture fisheries resulting in an inconsistent supply of the fish. For aquaculture, there is a need to improve its culture technology, develop seed production technology, and formulate an artificial diet. Various upgrading strategies to improve the industry and to increase the benefits derived by the key actors had been identified and presented in the paper.
Does the Behavioral Stress Response of Nile Tilapia, Oreochromis niloticus Breeders During Isolation Influence Seed Production?
Authors: Vera Cruz Emmanuel M. , Jimenez Eddie Boy T. , Apongol-Ruiz Bethzaida M.
Published: March 2021

This experiment assessed the effect of breeder’s behavioral stress response [i.e., eye color pattern (ECP)] during isolation on O. niloticus seed production. ECP change was marked by fractional color changes of the iris and sclera, which was transformed into scores ranging from 0 (no darkening) to 8 (total darkening). After isolation, breeders were divided into two social groups: proactive breeders (PB) were those with a mean ECP score of <2, and reactive breeders (RB) with a mean ECP score of >6. Two breeding cycles were done in six (1 m x 2 m x 1 m) net enclosures. Mean spawning rates (SR) in PB during the two cycles were 38.89±14.70% and 33.33±8.87% while 3.33±9.62% and 22.22±2.48% in the RB group. Total seed productions (TSP) in PB were 1,906.22±733.72 and 1,681.19±1,070.48 fry, and those in RB were 996.35±218.11 and 461.39±151.37 fry. There were no significant differences between the two groups on SR and TSP in both cycles. On seed production per female that spawned, however, significantly (P<0.05) higher means (796.33±77.68 and 726.33±124.08 fry) were observed in the PB compared to those in RB (522.73±54.68 and 335.83±44.98 fry). These results demonstrated that seed production in O. niloticus could be increased by selecting proactive breeders through the evaluation of their ECP during isolation.
Autism Spectrum Disorder
Authors:   Science Repository, Paul Satashree
Published: March 2021

Autism is considered a disorder of the brain and mainly runs in families. Researchers found that causes for autism are likely to be genetic, bio-chemical, metabolic, and neurological.
Record of Metatropiphorus emiliae from Laos (Heteroptera: Nabidae)
Authors: Kerzhner I.M.
Published: March 2021

Metatropiphorus emiliae Kerzhner is recorded from Laos for the fi rst time. Notes about characters of female are given.
Critical Discourse Analysis in Media Studies: A Review Research on Its Application in Indonesian Context
Authors: Anwar Anwar , Laraswati Asri , Ridhani Ridhani
Published: March 2021

This research examines the field of discourse analysis which has popularity in the media field and communication studies. The research is focused on the application of critical discourse analysis (CDA) in Indonesia. This study is especially interested in examining CDA’s variety of approaches. The goal of this review research is to discover and to know the role of CDA in the hidden ideologies in the media of discourse studies. The data in this study is on ten selected article journals to clarify the methods, ways, and to find in which CDA has been used in understanding social and educational phenomena. This study determined three themes in critical discourse analysis application, i.e. economic, political, and social contexts.
Shift of English Literature Learning from Classroom to Online: Preferences and Attitude of Bangladeshi Undergraduate Students
Authors: Islam Md. Zohorul
Published: March 2021

This paper explores the English Literature classes that are taught online in Bangladeshi universities and the attitude of the students towards these classes. The new-normal after the Covid-19 outbreak forced the students to attend classes online and their experience about the English Literature classes are investigated in this research. The total number of participants for this study was ninety-seven. The research was conducted on the students of the Department of English in four private universities in Bangladesh. A survey questionnaire was prepared consisting of twenty questions to collect the data online. The data was analysed with quantitative method of research. Digital statistical software Microsoft Excel used for the data analysis. The research finding shows that the students find poetry and short story classes effective and engaging in online classes but showed unfavorable attitude towards novel and drama classes. The results also show that the students want more opportunity to share their opinion in the class and preferred visual aids in online classes. This study implies that while the instructors and the students are going through an unprecedented challenge of learning English Literature in online classrooms, the obstacles can be mitigated through increasing interactive classroom discussion and precise use of multimedia tools while teaching different genres of English Literature.
Influnce of Using Photographs in Descriptive Writing to the Students of Nursing
Authors: Fini Fini widya fransiska
Published: March 2021

The objective of research was to know whether there was any influnces of using photographs in descriptive writing to the students of nursing.  In fact, many nurse students still find difficulties in writing. They still find difficulties in expressing what they want to write and how to write. In overcoming those problems, in certain condition to interest them, teacher can use many media to help them producing good written. One of the media is the using of photograph in teaching learning writing. Photograph can make students find ideas in writing and it can help them to make descriptive text when they look the picture. The population was taken from the nurse students of Universitas Muhammadiyah Pringsewu. The writer took two classes for experiment and control. The data collecting technique used the writing test. The teacher gave some topics and the students had to make composition by choosing one of the topic. The analyzing the data, the writer used ttest. After calculated the data, the writer found that was use photographs was x 2ratio = 6.01, and that was without use photographs was x2ratio = 3.93. It can conclude there was any influence of using photographs in descriptive writing to the students of nursing. The writer suggested to English teacher should be use photographs as a media in teaching writing.
An analysis of student's speaking difficulties in reporting a procedure text
Authors: Gea Fitri dian ningsih , Nurul hayati daely  , Yenni Julia Ningsih  , Melindah Harianja  , Melindah Harianja  , Rahmawati
Published: March 2021

Speaking skill is the skill that give us the ability to communicate effectively. The objective of the study were: (1) to find out the difficulties in reporting procedure text, (2) to find out the reason why do the students feel difficulties in reporting the procedure text, (3) to analysis why the difficulties occur at the studentsspeaking in reporting a procedure text.The population was all of the students first grade X-IPA of SMA Methodist 7 Medan 2019/2020 academic year. The sample of this research was the first grade X IPA consist 29 students in the class. The purpose of this study was to determine student knowledge in the text of the reporting procedure to determine student difficulties in the text of the reporting procedure. This researchers used qualitative method to know and examine the difficulties that occur and strive to resolve existing problems in speaking. From the results of research that has been conducted research, researchers found several that are classified through analysis, namly related to students difficulty in speaking, lack of vocabulary used, lack of pronouncation, and lack of knowledge about listening. And researchers used five aspects in giving scored namly Fluency, pronouncation, Accuracy, Clarity, and Performance skill.The researchers concluded in the other words that there was a significant analysis of students difficulties in reporting procedure text. It is suggested that English Teachers must practicing they speaking skill.
AN ANALYSIS OF STUDENTS’ VOCABULARY ABILITY IN FINDING VERB THROUGH SONG LYRICS IN SMP MARISI MEDAN.
Authors: Manurung Mian Ronauli , Munte Irvi Marca A. , Nisa Khairun , Tarigan Sri Ninta
Published: March 2021

This  research was  aimed to find out the students’ vocabulary ability  in finding verb through song lyrics. And this study have done in SMP MARISI Medan. Speaking is one of the language skills in English. That’s why mastery vocabulary is needed by every people. Vocabulary is a set of similar words within a person’s language. A vocabulary, usually developed with age, serves as as useful and fundamental tool for communication and acquiring knowledge. Teaching vocabulary through song is not only sing or reading lyric of song and fun so that is make the students passive but also process of teaching these vocabulary to be applied in activities in a form of communication.

The result of analysis showed that finding verb through song lyrics answered by students’. The students’ who got excellent is 18 (60%), the students’ who got good is 10 (33,3%) . so after the writer got there are score, the writer concluded that students’ who got excellent and good categorized able. The students’ who got categorized Bad2 (6,6%) students’. So, after the writer got there are score, the writer conclude that students’ who got enough and bad categorized unable in finding verb.

The researcher hopes that the students’ should be active in learning especially on vocabulary . because vocabulary is one of important skills in learning English. The students’ must develop their vocabulary so they can speak well in English. Moreover, the students’ may get more knowledge to improve their vocabulary in English.

Keywords  : vocabulary, verb, song lyrics.
HUBUNGAN KEKERABATAN BAHASA MELAYU RIAU DAN DIALEK AKIT (SEBUAH PENDEKATAN HISTORIS)
Authors: Fauzi Mohd. , Widayati Dwi
Published: March 2021

The research attempted to describe the kinship relationship between Riau Malay language and Akit dialect, a historical approach. This research was conducted in Padang Island, Kepulauan Meranti regency, using 200 Swadesh’s basic vocabulary as an analytical material, both lexicon equations were found about 80% by comparison of identical. The method used was descriptive-qualitative. The data was collected by using cakap method and simak method. The data analysis applies agih method with deletion technique, substitution technique. The data used was spoken language. The data was collected by using questionnaire, interviews, observation, and intuition methods. The source of data was Malay language Akit dialect. The result of the research showed that even though there are 80% similarities of both languages but there are some Akit words that still different from Malay language. These vocabularies must be preserved if it will not be lost in time since they are familiar with technology, many of their vocabularies are no longer used and they tend to use the Malay vocabularies.
KESELARAN MANUSIA DAN ALAM DALAM PANTUN BATOBO (KAJIAN EKOKRITIK DAN SEMIOTIK)
Authors: Puspita Alvi
Published: March 2021

This study examines Pantun Batobo, Kampar oral literature using ecocritical and semiotic theories. Pantun Batobo is a poem sung by batobo actors (mutual cooperation in farming) in the cultural areas of Kampar, Kuantan Singgigi, and Inderagiri. This pantun is intended as a remedy for fatigue because batobo actors work from morning to evening. This pantun can be classified into the cultural products of an agrarian society. To study the pantun, ecocritical and semiotic theories are used. Methods used interview techniques and literature while for data analysis used descriptive analysis methods. The results of this study are found the concept of harmony between humans and nature in the Pantun Batobo.
Quasifical Operations in the Sector of Enterprises with the State Participation as an Instrument of State Regulation of the Economy
Authors: Shvets Nataliia , Tkachuk Iryna , Kobelia Mariana
Published: March 2021

Actuality. The risks of the state-owned enterprises are largely caused by unjustified quasi-fiscal operations in the sector of such enterprises. The main aim of the article is to reveal the theoretical essence of the category "quasi-fiscal operations" as an instrument of the state regulation of the economy in the sector of enterprises with state participation. Research results. The article highlights the approaches to the interpretation of quasi-fiscal operations by both scientists-theorists and high-authority organizations in this field, which allowed to summarize the typical features of quasi-fiscal operations in the sector of enterprises with state participation. The preconditions for the introduction of quasi-fiscal operations in the sector of enterprises with state participation and instruments for their implementation are highlighted. The approach to the classification of quasi-fiscal operations in the sector of enterprises with state participation taking into account the subjects of implementation, the impact on the budget and the sphere of activity of enterprises is substantiated. The negative consequences of the use of quasi-fiscal operations in the sphere of enterprises with state participation are substantiated. Conclusions. Given the peculiarities of quasi-fiscal operations in the field of enterprises with state participation, the state must assess the consequences of their use separately for each case, taking into account economic, social, and political and other factors inherent in the country. The elements of scientific novelty. Further studies have been devoted to highlighting the role of quasi-fiscal operations in the field of state-owned enterprises as an instrument for the state regulation of the economy. Practical significance. The main results of the study can be used as the basis for further scientific research on the activities of enterprises with state participation, and will also be useful for decision-making by public authorities on the use of quasi-fiscal operations in this sector.
Analisis Pengaruh Perubahan Beban Generator Terhadap Efsiensi Kinerja PLTU Bosowa Energi Jeneponto Unit 2
Authors: Pangkung Andreas , Nawir Herman , Santoso Aditya Nugraha Adji
Published: March 2021

This study aims to determine the effect of changes in generator load on efficiency performance in steam power plants and to determine the amount of input power in the boiler. Data collection was carried out at PT. Bosowa Energi PLTU Jeneponto. The data are the power output, fuel consumption, and the calorific value of the fuel. Then perform data analysis by calculating input power and efficiency. From the result of the study, the highest efficiency is on May 20, 2018 at 18.00 with a load of 90.00 MW, namely 55.68% and the lowest efficiency is on May 12, 2018 at 03.00 with a load of 64.98 MW, namely 22.69%. The highest boiler input power based on the analysis results was on May 3, 2018 at 20.00, namely 356.61 MW, and the lowest boiler input power based on the analysis was on May 15, 2018 at 07.00, namely 128.14 MW.
EEPSA as a core ontology for energy efficiency and thermal comfort in buildings
Authors: Esnaola-Gonzalez Iker , Bermúdez Jesús , Fernandez Izaskun , Arnaiz Aitor
Published: March 2021

Achieving a comfortable thermal situation within buildings with an efficient use of energy remains still an open challenge for most buildings. In this regard, IoT (Internet of Things) and KDD (Knowledge Discovery in Databases) processes may be combined to address these problems, even though data analysts may feel overwhelmed by heterogeneity and volume of the data to be considered. Data analysts could benefit from an application assistant that supports them throughout the KDD process and aids them to discover which are the relevant variables for the matter at hand, or informing about relationships among relevant data. In this article, the EEPSA (Energy Efficiency Prediction Semantic Assistant) ontology which supports such an assistant is presented. The ontology is developed on the basis that a proper axiomatization shapes the set of admitted models better, and therefore, establishes the ground for a better interoperability. On the contrary, underspecification facilitates the admission of non-isomorphic models to represent the same state which hampers interoperability. This ontology is developed on top of three ODPs (Ontology Design Patterns) which include proper axioms in order to improve precedent proposals to represent features of interest and their respective qualities, as well as observations and actuations, the sensors and actuators that generate them, and the procedures used. Moreover, the ontology introduces six domain ontology modules integrated with the ODPs in such a manner that a methodical customization is facilitated.
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2
Authors: Li Yaling , Chandra Thakur Prakash , Song Xiong , Nie Liangui , Liu Maojun , Yi Jiali , Zheng Xia , Chu Chun , Yang Jun
Published: March 2021

OBJECTIVE: We waimed to investigate whether H2S can relieve the myocardial fibrosis caused by doxorubicin through Keap1-Nrf2. METHODS: Sprague-Dawley (SD) rats were randomly divided into four groups: normal control group (Control); DOX model group (DOX); H2S intervention model group (DOX+H2S); H2S control group (H2S). DOX and DOX+H2S group were injected with doxorubicin (3.0 mg/kg/time) intraperitoneally. Both of the Control group and H2S groups were given normal saline in equal volume, 2 weeks later, DOX+H2S and H2S group were controlled with NaHS (56 μmol/kg/d) through the abdominal cavity, while the Control and DOX group were injected with normal saline of the same dosage intraperitoneally. RESULTS: Myocardial injury and myocardial cell apoptosis were significantly increased, the H2S content in myocardial tissue was remarkably down-regulated, the expression levels of MDA, Keap1, caspase-3, caspase-9, TNF-α, IL1β, MMPs and TIMP-1 in rat myocardial tissue was significantly up-regulated (P< 0.05), and the expression levels of GSH, NQO1, Bcl-2 were down-regulated compared with those of control group. The above results can be reversed by the DOX+H2S group. There is no statistically significant difference between the Control group and the H2S control group. CONCLUSIONS: These results suggest that H2S can improve DOX-induced myocardial fibrosis in rats, and the keap1/Nrf2 signaling pathway, oxidative stress, inflammation, and apoptosis may be involved in the mechanism.
Molecular mechanism underlying the hypolipidemic effect of Shanmei Capsule based on network pharmacology and molecular docking
Authors: Wang Qian , Du Lijing , Hong Jiana , Chen Zhenlin , Liu Huijian , Li Shasha , Xiao Xue , Yan Shikai
Published: March 2021

BACKGROUND: Shanmei Capsule is a famous preparation in China. However, the related mechanism of Shanmei Capsule against hyperlipidemia has yet to be revealed. OBJECTIVE: To elucidate underlying mechanism of Shanmei Capsule against hyperlipidemia through network pharmacology approach and molecular docking. METHODS: Active ingredients, targets of Shanmei Capsule as well as targets for hyperlipidemia were screened based on database. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment were performed via Database for Annotation, Visualization, and Integrated Discovery (DAVID) 6.8 database. Ingredient-target-disease-pathway network was visualized utilizing Cytoscape software and molecular docking was performed by Autodock Vina. RESULTS: Seventeen active ingredients in Shanmei Capsule were screened out with a closely connection with 34 hyperlipidemia-related targets. GO analysis revealed 40 biological processes, 5 cellular components and 29 molecular functions. A total of 15 signal pathways were enriched by KEGG pathway enrichment analysis. The docking results indicated that the binding activities of key ingredients for PPAR-α are equivalent to that of the positive drug lifibrate. CONCLUSIONS: The possible molecular mechanism mainly involved PPAR signaling pathway, Bile secretion and TNF signaling pathway via acting on MAPK8, PPARγ, MMP9, PPARα, FABP4 and NOS2 targets.
Energy absorption at lower limb joints in different foot contact strategies while descending stairs
Authors: Jeon Hyeong-Min , Lee Ki-Kwang , Lee Jun-Young , Shin Ju-Hwan , Eom Gwang-Moon
Published: March 2021

BACKGROUND: Joint loads in different walking strategies during stair descent have been investigated in terms of the joint moment in association with the risk of osteoarthritis. However, the absorption mechanisms of the potential energy loss are not known. OBJECTIVE: This study aims to compare the mechanical energy absorptions in lower limb joints in different initial foot contact strategies. METHODS: Nineteen young subjects walked down on instrumented stairs with two different strategies, i.e., forefoot and rearfoot strike. Power and energy at lower limb joints during stance phase were compared between strategies. RESULTS: Lower limb joints absorbed 73 ± 11% of the potential energy released by descending stairs and there was no difference between strategies. Rearfoot strategy absorbed less energy than forefoot strategy at the ankle joint in the 1st phase, which was compensated mainly by more energy absorption at the knee in the 2nd phase and less energy generation at the hip joints in the 3rd phase. CONCLUSION: The results suggest that a leg absorbs most of the potential energy while descending stairs irrespective of the walking strategies and that any reduction of energy absorption at one joint is compensated by other joints. Greater energy absorption at the knee joint compared to the other joints suggests high burden of knee joint muscles and connective tissues during stair-descent, which is even more significant for the rearfoot strike strategy.
Bioinformatics analysis of Myelin Transcription Factor 1
Authors: Ding Hongjun , Li Yanju , Zhang Yanlong , Meng Huipeng , Wang Keqiang , Sun Qian , Li Xichuan , Dong Huajiang , Chen Long , He Feng
Published: March 2021

BACKGROUND AND OBJECTIVE: We aimed to further study the role of Myelin Transcription Factor 1(MyT1) in tumor and other diseases and epigenetic regulation, and better understand the regulatory mechanism of MyT1. METHODS: Using bioinformatics analysis, the structure and function of MyT1sequence were predicted and analyzed using bioinformatics analysis, and providing a theoretical basis for further experimental verification and understanding the regulatory mechanism of MyT1. The first, second and third-level structures of MyT1 were predicted and analyzed by bioinformatics analysis tools. RESULTS: MyT1 is found to be an unstable hydrophilic protein, rather than a secretory protein, with no signal peptide or trans-membrane domain; total amino acids located on the surface of the cell membrane. It contains seven zinc finger domains structurally. At sub-cellular level, MyT1 is localized in the nucleus. The phosphorylation site mainly exists in serine, and its secondary structure is mainly composed of random coils and alpha helices; the three-dimensional structure is analyzed by modeling. CONCLUSIONS: In this study, the structure and function of MyT1 protein were predicted, thereby providing a basis for subsequent expression analysis and functional research; it laid the foundation for further investigation of the molecular mechanism involved in the development of diseases.
Preliminary study on the new wound monitoring technology using co-planar waveguide sensor: Modeling and simulation
Authors: Zhang Liang , Ji Zhenyu
Published: March 2021

BACKGROUND: Wound monitoring is very meaningful for the clinical research, diagnosis and treatment. But the existing wound monitoring technology is hard to meet the needs of modern medical care in terms of real-time, non-invasive and anti-interference. OBJECTIVE: To solve this problem, this paper proposed a new kind of monitoring technology based on the co-planar waveguide transmission line theory and assessed the application value of this method as a wound monitoring technology. METHODS: The simplified wound model included the skin, fat, muscle, tissue fluid and bandage and a new co-planar waveguide sensor were designed and established. All of the simulation was achieved in the electromagnetic special software. The data processing method was based on the transmission line theory. RESULTS: Detailed analyses of the results from the simulation were conducted. The sensor has a good monitoring effect in the low frequency band. The monitoring results could be influenced by the thickness of the bandage outside the wound. The thickness of the bandage should not be larger than 10 mm. The effective monitoring area of the sensor is 30 × 20 mm2. CONCLUSIONS: The proposed sensor based on the CPW transmission principle in this paper has good wound monitoring potential.
Age prediction based on a small number of facial landmarks and texture features
Authors: Wang Mengjie , Chen Weiyang
Published: March 2021

BACKGROUND: Age is an essential feature of people, so the study of facial aging should have particular significance. OBJECTIVE: The purpose of this study is to improve the performance of age prediction by combining facial landmarks and texture features. METHODS: We first measure the distribution of each texture feature. From a geometric point of view, facial feature points will change with age, so it is essential to study facial feature points. We annotate the facial feature points, label the corresponding feature point coordinates, and then use the coordinates of feature points and texture features to predict the age. RESULTS: We use the Support Vector Machine regression prediction method to predict the age based on the extracted texture features and landmarks. Compared with facial texture features, the prediction results based on facial landmarks are better. This suggests that the facial morphological features contained in facial landmarks can reflect facial age better than facial texture features. Combined with facial landmarks and texture features, the performance of age prediction can be improved. CONCLUSIONS: According to the experimental results, we can conclude that texture features combined with facial landmarks are useful for age prediction.
A study of the effects of hydroxyapatite bioceramic extract on Ang/Tie2 system of umbilical vein endothelial cells
Authors: Zhang Xueyang , Liu Yanyi , Su Yuan , Fan Xiaohui , Hu Fei
Published: March 2021

OBJECTIVE: We aimed to investigate the effects of hydroxyapatite bioceramic extract on Ang/Tie2 system and cell proliferation of umbilical vein endothelial cells. METHODS: Human umbilical vein endothelial cells (HUVECs) were used in this research. There are two induvial groups, control group and hydroxyapatite bioceramics extract treatment group. Cell Counting Kit-8 (CCK-8) was used to evaluate cell proliferation. Western blot and real time quantitative PCR (Q-PCR) were used to evaluate the protein and mRNA expression levels of Ang1, Ang2 and Tie2 in Ang/Tie2 system, respectively. All the results were statistically analyzed by Spss19.0. All data were presented as mean ± standard error of mean (SEM). Student’s t-test was performed to determine the differences among grouped data. RESULTS: Hydroxyapatite bioceramics extract showed no effect on the cell morphology and cell proliferation of HUVECs. Interestingly, we found that both Ang2 and Tie2 protein and mRNA level were markedly increased by hydroxyapatite bioceramics extract. CONCLUSIONS: Hydroxyapatite bioceramic extract showed no cytotoxicity to HUVECs, and might regulate vascular remodeling by mediating Ang/Tie2 system.
Систематизація та кодифікація законодавства: концептуальний вимір.
Authors:   Alfred Nobel University, Пєтков С.В.
Published: March 2021

Статтю присвячено питанням систематизації та кодифікації законодавства, оскільки ці процеси є формою правотворчості і їх основне призначення полягає в забезпеченні найбільш повного право- вого регулювання певної сфери суспільних відносин шляхом прийняття логічно досконалих норма- тивних актів комплексно-узагальнюючого характеру. На підставі критичного аналізу норм пострадян- ської юриспруденції запропоновано сучасне розуміння сутності та ролі адміністративного законодав- ства з урахуванням його узгодженості з європейськими стандартами. Виділено основні проблемні питання, неузгодженості та юридичні колізії в цьому напрямі.
Розвиток національного законодавства у сфері соціального захисту населення.
Authors:   Alfred Nobel University, Червякова О.В.
Published: March 2021

Проаналізовано систему соціального законодавства України, що є достатньо розгалуженою, вона включає в себе акти загальної дії та акти спеціальної дії, які спрямовані на певні категорії та гру- пи соціально вразливих верств населення. Зокрема держава гарантує соціальний захист, передбаче- ний Конституцією України, право на соціальний захист гарантується загальнообов’язковим держав- ним соціальним страхуванням за рахунок страхових внесків громадян, підприємств, установ та ор- ганізацій, а також бюджетних та інших джерел соціального забезпечення; створення мережі дер- жавних, комунальних та приватних установ для догляду за інвалідами. Зазначено, що потребує по- дальшого вдосконалення законодавство щодо соціального захисту мирного (цивільного) населення, яке постраждало внаслідок бойових дій чи збройних конфліктів. Водночас низкою підзаконних актів встановлюється порядок надання щомісячної адресної допомоги внутрішньо переміщеним особам для покриття витрат на проживання, у тому числі на оплату житлово-комунальних послуг; особливос- ті реалізації прав деяких категорій осіб на загальнообов’язкове державне соціальне страхування; по- рядок використання коштів, що надійшли від фізичних та юридичних осіб для надання одноразової грошової допомоги постраждалим особам та внутрішньо переміщеним особам; здійснення соціаль- них виплат внутрішньо переміщеним особам; питання фінансування бюджетних установ, здійснен- ня соціальних виплат населенню та надання фінансової підтримки окремим підприємствам і органі- заціям Донецької та Луганської областей, а також інших платежів з рахунків, відкритих в органах Каз- начейства; перелік населених пунктів, на території яких органи державної влади тимчасово не здій- снюють свої повноваження.
Висвітлено процес формування державної міграційної політики в Україні. Констатується, що із середини 2010-х рр. міграція з нашої держави набула масових масштабів. Наслідки вказаного про- цесу можуть бути як негативними, так і позитивними для українського суспільства. Визначається, що завданням внутрішньої політики нашої держави є максимальне використання позитивних наслід- ків масової трудової міграції. Розглянуто два періоди формування української нормативно-право- вої бази у сфері зовнішньої трудової міграції: 2000-ні рр. як період приведення нормативної бази у відповідність до Основного Закону України і період 2010-х рр. – реагування на масову трудову емі- грацію. Проаналізовано низку чинних законодавчих та підзаконних нормативно-правових актів, що опосередковано чи безпосередньо стосуються зовнішньої трудової міграції.
Authors:   Alfred Nobel University, Цалин Р.В. Р.В.
Published: March 2021

Статтю присвячено характеристиці правовстановлюючих документів на відходи. Зокрема зау- важується, що правовстановлюючими документами на відходи можуть бути: договори (купівлі-про- дажу, міни, дарування тощо); свідоцтво про право на спадщину; рішення суду; передавальний акт, розподільчий баланс; статут юридичної особи в комплексі з рішенням уповноваженого органу юри- дичної особи про внесення відходів до статутного капіталу юридичної особи (цей перелік не є ви- черпним). Вноситься та обґрунтовується пропозиція щодо посвідчення права власності на відходи, що утворюються в процесі діяльності власника, паспортом відходів, а також пропонуються зміни до законодавства щодо форми та змісту паспорта відходів. Відповідно до чинного законодавства Украї- ни, відходи виступають як конкретний об’єкт власності. Відходи, що перебувають у процесі обігу, мо- жуть негативно впливати на стан навколишнього середовища, за що покладається відповідальність на індивіда – їх власника. Тому ці питання потребують конкретного правового регулювання екологіч- ного права. Таким чином, проблема засвідчення права власності на відходи, що утворюються в про- цесі діяльності власника відходів, має бути вирішена шляхом удосконалення правового регулюван- ня відносин поводження з відходами як конкретного об’єкта власності.
Сутність поняття «адміністративна юстиція» як елемента правової держави
Authors:   Alfred Nobel University, Галабурда Н.А. Н.А.
Published: March 2021

Статтю присвячено питанням теоретичного обґрунтування та надання правознавчої інтерпре- тації поняттю «адміністративна юстиція», визначено її сутність та особливості. З’ясовано причини, що визначають існування інституту адміністративної юстиції та необхідність його подальшого розвитку. Адміністративна юстиція є обов’язковим елементом системи зовнішнього контролю щодо законнос- ті дій органів публічної влади та їх посадових осіб у частині прийнятих ними актів або вчинених ними дій (бездіяльності), які порушують передбачені законом права фізичних чи юридичних осіб, що за- безпечуються системою судових органів у передбаченому адміністративно-процесуальному поряд- ку. З одного боку, вона захищає суб’єктивні права громадян, а з іншого – за допомогою судової прак- тики забезпечує законність діяльності органів державної влади і, таким чином, сприяє зміцненню правопорядку в державі.
До питання про місце політичних прав і свобод людини й громадянина в системі конституційних прав і свобод людини й громадянина в Україні.
Authors:   Alfred Nobel University, Заворотченко Т.М.
Published: March 2021

Розглянуто проблему визначення місця політичних прав і свобод людини й громадянина в сис- темі конституційних прав і свобод особистості. На основі аналізу ознак політичних прав і свобод ви- значено, які органи державної влади та суб’єкти громадянського суспільства беруть участь у вирішен- ні практичних питань, пов’язаних з реальним застосуванням всіх політичних прав і свобод людини в житті суспільства. Досліджено роль державних органів у механізмі забезпечення політичних прав і свобод особистості. Вирішено завдання, що були поставлені при написанні статті. З’ясовано роль і значення політичних прав і свобод людини в системі конституційних прав і свобод людини й грома- дянина. Розкрито основні ознаки політичних прав і свобод. Досліджено особливості впливу політич- них прав і свобод на громадянське суспільство. Зазначено, що Конституція України приділяє особли- ву увагу питанню конституційного закріплення політичних прав і свобод людини й громадянина. Це є цілком закономірним, оскільки політичні права і свободи людини й громадянина в сучасних умовах стали загальновизнаною найвищою суспільною цінністю. Визначено та надано характеристику озна- кам політичних прав і свобод людини та громадянина.
Cultural Guidelines for Commercial Production of Interiorscape Aglaonema
Authors: Chen Jianjun , McConnell Dennis B. , Henny Richard J. , Everitt Kelly C.
Published: March 2021

The intent of this article is to describe common Aglaonema species and cultivars in the foliage plant industry, provide guidelines on their culture and interior use, and list physiological problems encountered in both production and in the interiorscape. This document is ENH957, one of a series of the Environmental Horticulture Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Original publication date July 30, 2003.

ENH957/EP160: Cultural Guidelines for Commercial Production of Interiorscape Aglaonema (ufl.edu)