bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of an in vitro hairy root induction system in different soybean cultivars for gene expression and genome editing studies
Authors: Nhu Thao Le Thi , Hong Nhung Nguyen , Quang Huy Le , Phuong Thao Bui , Thu Ngoc Le , Bich Ngoc Pham , Hoang Ha Chu , Tien Phat Do
Published: October 2021

Hairy root induction system has been widely applied for studies of gene function, gene expression, and genome editing in numerous plant species. In this study, we developed and evaluated the performance of an in vitro hairy root induction system via Agrobacterium rhizogenes on several Vietnamese and international soybean cultivars. The efficacy of in vitro hairy root induction and of transformation using this system was varied and depended on soybean cultivars as well as transgenic constructs. The hairy root induction frequency of different soybean cultivars ranged from 61.67% to 100% after 5 days on culture medium. From 43.8% to 79.8% of hairy roots transformed with GFP-expressing construct showed transgene expression, while that for the construct with the gus gene was from 38.07% to 72.33%. Among tested soybean cultivars, DT26 demonstrated the highest transformation and gene expression efficacy with both investigated vectors. This hairy root induction system was further utilized for targeted knockout mutagenesis via CRISPR/Cas9 of two genes which are G03 and G09 in the DT26 soybean cultivar. Successful mutagenesis in the regions of targeted genes was confirmed by shifted and multiple bands compared to which of non-transgenic hairy root in PAGE analysis. Sequencing results of targeted regions presented various nucleotide deletions ranging between -3 bp and -25 bp in size in both two genes of interest. This study laid an important basis for future gene function studies and targeted gene editing investigations on soybean plants in Vietnam.
Olexsii Artemovych Dynnik
Authors: "ORTHOPAEDICS, TRAUMATOLOGY AND PROSTHETICS" Staff of
Published: October 2021

The article is devoted to the head of the laboratory of orthoses and biomaterials of the Sytenko Institute of Spine and Joint PathologyNational Academy of Medical Sciences of Ukraine Candidate of Medical Sciences, Associate Professor  O. A. Dynnik
Denys Dmytrovych Bitchuk
Authors: "ORTHOPAEDICS, TRAUMATOLOGY AND PROSTHETICS" Staff of
Published: October 2021

On May 24, 2021, Professor Denis Dmytrovych Bitchuk, an outstanding scientist, talented clinician, excellent pedagogue, Head of the Department of Orthopedics, Traumatology and Military Field Surgery of Kharkiv National Medical University (1989−2008), passed away.
Biochemical and immunological blood parameters in patients with inflammatory complications after spine screw fixation
Authors: Radchenko Volodymyr , Leontyeva Frieda , Barkov Oleksandr , Tuliakov Vladyslav , Korzh Iryna
Published: October 2021

As a result of screw fixation at the surgical treatment of patients with spinal diseases, certain complications may occur, of which soft tissues inflammation is frequent. Therefore, it is especially important to study the metabolic status of patients before surgery to determine the increased possibility of complications. Objective. To study the biochemical and immunological blood serum parameters and determine their diagnostic sensitivity in patients with the thoracic and lumbar spine diseases after screw fixation with postoperative inflammatory response. Methods. Comparisons of blood parame­ters were carried out in two groups of 20 patients in each group: the first one — patients at whom the postoperative period passed without complications, the second group — a soft tissues inflammation around the metal structure was observed in the postoperative period. Blood for the study was taken before the surgery on an empty stomach for determination of: C-reactive protein (CRP), sialic acid, alkaline phosphatase (ALP) activity, haptoglobin, content of total chondroitin sulfate (ChS), glycoproteins, circulating immune complexes (CIC), the rate of spontaneous lymphocyte mig­ration, the level of lymphocyte migration with antibodies to bone and cartilage antigens. For quantitative characterization of diagnostic reliability of laboratory test was used the criterion of diagnostic sensitivity. Results. In patients with postoperative soft tissue inflammation around the metal device before surgery, the following indicators were the most informative: the content of ChS (95 %), CRP (80 %), glycoproteins (95 %), haptoglobin (92 %), ALP activi­ty (80 %), sialic acid content (90 %), CIC concentration (70 %), the rate of spontaneous lymphocyte migration (65 %). Conclusions. The laboratory parameters complex with the highest diagnostic sensitivity can be recommended for the selection of preventive measures in the preoperative period, which will improve the results of surgical treatment, reduce its duration and costs.
Limiting factors in stimulating and sustaining interest in psycho-productive skills acquisition in secondary school agricultural science
Authors: Onanuga Peter Abayomi , Banjo James Olanrewaju Sunday
Published: October 2021

In the study reported on here we investigated factors impeding the stimulation and sustenance of students’ interest in the acquisition of psycho-productive skills in senior secondary school agricultural science. We used the classical design for change experiments or before-after measures as the research design. Two methods of teaching, namely demonstration and conventional teaching were used with the experimental and control groups (87 subjects) from 2 schools in the Ijebu-East Local Government Area, Ogun State, Nigeria. A self-reporting scale exposed the students’ perceptions of limiting factors such as seeing agriculture as a dirty job, a school subject meant for never-to-do-well, dull students, and as punishment for erring students. Of the 12 factors listed as stimulating and sustaining students’ interest, the subjects identified 8 as limiting ones. The results from the mean, standard deviation and t-test indicate that there was significant difference between the factors identified by the experimental and control groups. The results also reveal that there was a significant difference in the factors identified by male and female subjects. This could have been as a result of gender stereotyping regarding agricultural practices in some parts of the study area. It was suggested, among others, that the agricultural science teacher should make efforts to incorporate innovative teaching approaches like demonstration methods in classroom practice coupled with infusion of practical periods to enhance psycho-productive skills acquisition. The vocational agriculture curriculum should include an approach to easily measure a combination of psycho-productive, affective and cognitive skills rather than mere cognitive skills.
Study on the utilization behaviour of online journals by the students of UAS-Dharwad
Authors: Ramachandra V. A. , Mitrannavar D.H. , Naik A.D.
Published: October 2021

The study was taken up in University Agricultural Sciences, Dharwad (UAS-D), UAS-D offered PG programme in 24 disciplines and Ph.D programme in 17 disciplines, among them 10 disciplines were selected. The sample size was 50 students consisting 30 post graduates and 20 doctoral programme students using Simple Random Sampling technique. Five students were selected from each of the 10 selected departments using simple random sampling technique. Percentage analysis was used for data analysis. About two-third of the students referred online journals for their purpose of assignment, seminar and research. Majority of the students faced the problems like getting user name, password, long time to download an article, read only content and limited availability of online journals are the major difficulties faced in access and usage of online journals. These problems could be addressed to enhance the learning of online journals among the students of UAS-D.
Farmer field school : An approach beyond technology transfer
Authors: Singh Amandeep , Singh Dharminder , Dhaliwal R. K.
Published: October 2021

Farmer field school is an innovative extension approach, emerged in rice crop and gradually diversified to vegetables, cotton, livestock and other crops. FFS originated from Indonesia, is presently being conducted in many countries with local adaptations and institutionalization. FFS is a groupbased learning process that includes hands-on training methods, carried out through field observations, agro-ecosystem analysis at subgroup level, agro-ecosystem analysis at school level and special topics. Participants of farmer field schools are made to learn through direct real-life experiences to maximize retention of farm information. During the period 1994-2013, total 14,617 FFS were organized to train 58,422 agricultural extension officers and 4,39,508 farmers in the country. Evaluation studies reported that the FFS approach has empowered farmers in knowledge acquisition, analytical skills, critical thinking, problem-solving skills and reflecting an increase in yield, reduction in pesticide use and farm-level returns. Sustained diffusion from field school graduates to neighboring farmers still lacks convincing evidences. Effective FFS essentially require backstopping by experienced facilitators, appropriate fund release mechanism, proper logistics, regular monitoring and participation of farmers.
Quality of life of young awardee farm women of University of Agricultural Sciences, Dharwad
Authors: Balambeed Suma , Channal Geeta P.
Published: October 2021

Indian economy is predominantly rural and agriculture oriented supporting 50 per cent of its population. Increasing population and declining trend in the average size of land holding poses a serious problem to the Indian farmers for maintaining a decent quality of life. Quality of life is the degree to which a person enjoys the important possibilities of his/her life. The ultimate aim of an individual is to lead a happy life. A happy life is one in which the basic needs are met with at least some comforts. The present study deals with the quality of life of young awardee farm women. This study was conducted in Dharwad, Gadag and Haveri districts of Karnataka. The woman who had received Yuva Shresta Krishi Mahile award during 2014-2017 was purposively selected. A total of 60 young awardee farm women were selected as a sample for the study from 17 talukas conferred by the UAS Dharwad. Prestructured interview schedule was used to collect the data. Suitable statistical tools like frequency, percentage and indices were used for analysis of the data. The important findings of the study revealed that, cent per cent of the awardee farm women belonged to young age group (< 35 years) had high school education and from big family size (43.33 %) belonged to joint family (51.67 %), had medium farming experience (60.00 %) and had big land holding (38.33%). Around 72.00 per cent of the respondents had high quality of life, 28.33 per cent had medium quality of life and none of the respondents belonged to low quality of life.
[RETRACTED] VigorNow Male Enhancement v1
Authors: not provided health
Published: October 2021

[RETRACTED]

VigorNow Many men think of this upgrade as directly supplementation that helps to increase sexual limitations.
FORMATION OF THE UKRAINIAN LEGAL DOCTRINE CONCERNING QUALIFICATION OF THE CRIMINAL OFFENSES COMMITTED BY THE ORGANIZED CRIMINAL GROUPS IN CONTEXT OF AMENDING CHANGES TO LEGISLATION ON CRIMINAL LAW
Authors: Ptaschenko D.
Published: October 2021

The Article 1 of the Constitution of Ukraine regulates: Ukraine is a sovereign and independent, democratic, social, legal state. One of the destabilizing factors in building the rule of law is the commission of criminal offenses by organized criminal groups. Due to the changes in the criminal legislation during the last two years, the criminal law norms have undergone significant changes, which directly or indirectly affect the qualification of criminal offenses committed by organized criminal groups. Given the changes in criminal law, the qualification of criminal offenses committed by organized criminal groups requires uniform systemic approaches, primarily at the level of judicial law enforcement practice. The formation of the Ukrainian legal doctrine on the qualification of criminal offenses committed by organized criminal groups is one of the significant auxiliary guidelines in the formation of such law enforcement practice. To achieve this goal and the defined objectives, the following methods were applied in the study: logical and normative – for the analysis of criminal law on the qualification of criminal offenses committed by organized criminal groups; system analysis – when considering judicial law enforcement practice (first of all, the Supreme Court and the Supreme Court of Ukraine) of the qualification of criminal offenses committed by organized criminal groups. The legislation strengthens criminal liability for criminal offenses by organized criminal groups, in particular, as evidenced by the amendments to the Criminal Code under the Law of Ukraine "On Amendments to Certain Legislative Acts of Ukraine on Liability for Crimes Committed by the Criminal Community" dated by the 4th of June 2020. Before the formation of new approaches to the doctrine of criminal law and law enforcement judicial practice on the qualification of criminal offenses (crimes), a specific part of which is provided by h.ch. 1-5 art. 255 of the Criminal Code, the indirect reference is the provision of the resolution of the Plenum of the Supreme Court of Ukraine of December 23, 2005 №12 "On the practice of consideration by courts of criminal cases on crimes committed by stable criminal groups." Keywords: criminal offenses, criminal community, criminal organization, organized group, creation of a criminal community, leadership of a criminal community, organized criminal groups.
DEVELOPMENT OF SCIENTIFIC AND TEACHING ACTIVITIES IN THE FIELD OF HEALTH LAW AS A PREREQUISITE FOR A CONTEMPORARY LAWYER'S PERSONALITY FORMATION (EXPERIENCE OF THE TARAS SHEVTCHENKO NATIONAL UNIVERSITY OF KYIV)
Authors: Hrevtsova R.
Published: October 2021

Health care is one of the most important spheres of activities of the state and society. The functioning and development of health care require proper legal support that is possible if there are enough qualified lawyers equipped with profound knowledge and skills in the health law area. The paper discusses the concept of health law that is new for the Ukrainian legal science as well as its integral components – medical law, public health law, and pharmaceutical law. The experience of teaching courses pertaining to the realm of health law at the Taras Schevtchenko National University of Kyiv that is the leader of Ukrainian higher education, particularly the legal one, is examined. It is the law faculty (currently – the Institute of Law) of the said University whereat the innovative discipline "Legal regulation of public health" ("Public Health Law") started to be taught for the first time in Ukraine. In 2019, the LLM specialization (the elective block of courses) "Health Law" that was unique for Ukraine, was introduced. The article mentions the key goals at the attainment of which the courses studied within the framework of the "Health Law" LLM program (totally ISSN 1728-2195 ЮРИДИЧНІ НАУКИ. 3(118)/2021 ~ 21 ~ 12 disciplines), are targeted. It analyzes the list and content of the courses belonging to the said LLM specialization that can be conditionally divided into three blocks: the key disciplines covering the "components" of health law; the disciplines ensuring understanding of the peculiarities of activities in the sphere of health care and the legal tools used for the governance in health care and management of healthcare institutions; and the courses directed at covering the topical issues of law and ethics in health care and at acquiring practical skills of protection of rights of healthcare actors. The paper points out that while teaching courses falling within the "Health Law" LLM specialization, major stress was made on getting students acquainted with the realities of practice. It pays attention to the use of modern methods and approaches to teaching as well as education technologies that allowed ensuring high efficiency of education, particularly under the conditions of lockdown caused by the spread of coronavirus disease COVID-19. The article also outlines major components of the education and scientific activity carried out at the Taras Shevtchenko National University of Kyiv, including that of the Education and Research Center for Medical Law of the Institute of Law. The conclusion is made that а scientific school of health law has been established at the Taras Shevtchenko National University of Kyiv. Keywords: health law, medical law, pharmaceutical law, health care, public health, public health law, LLM specialization, education, science.
Analysis of Individual and Social Forms of Psychological Trauma
Authors: Krasilo A.I.
Published: October 2021

The article attempts to determine its socio-psychological essence through the analysis of the social form of psychological trauma, as well as to identify the psychological nature of the pathological neoplasms that have arisen as a result of it, the specificity of which largely determines the methods and technology of personalistic counseling. These neoplasms are both individual psychological, including the sphere of experiences, and socio-psychological, affecting the relationship of the victims. The integration of the dominant parasitic "Ego" into the depth of the victim's personality, up to the very first level of the primary trusting relationship between the all-powerful and loving mother and a helpless child, we called the introjection of the personifier. As a result of the analysis, we come to the need for a specific restructuring of the irrational relationships of the victim with two other participants in the traumatic situation: the beneficiary, who receives personal benefits from this situation, and the reference group of the victim, who is traumatically personified by him in the image of an impersonal social personifier. The main methods of victims’ examination during the thirty years of counseling were: clinical conversation and projective methods of personality research.
Adolescents’ communication on the Internet: the boundaries of normativity
Authors: Kiriukhina D.V.
Published: October 2021

The emergence and spread of the Internet has led to the fact that the virtual space has become a new source of communication, especially for adolescents, active users. However, such communication differs significantly from real interaction in the absence of various restrictions that affect the quality of communication and can lead to complete disregard of generally accepted moral norms. The purpose of the article is to analyze the features of adolescents ' communication on the Internet and the boundaries of normativity that they tend to cross, as well as the reasons for their violation. The article considers the positive and negative impact of Internet communication on the personality of schoolchildren, communication models, revealing the distinctive features of network interaction of young people and their negative consequences. The problems of compliance with the norms of communication and etiquette are analyzed, which, among other things, can develop into a more aggressive form – cyberbullying. Statistical data on violations of the boundaries of normativity when communicating with young people on the Internet in a number of countries are presented. The main directions of prevention of non-normative interaction of adolescents in the virtual space are highlighted. The study of the peculiarities of communication of adolescents in the digital environment will reveal in more detail the understanding of the causes of the spread of virtual aggression and will be able to contribute to the development of the level of communication culture of young people on the Internet.
Biobanking in the structure of legal regulation of genetic research: experience of the Nordic Countries
Authors: Przhilenskiy V. I.
Published: October 2021

The article examines the experience of legal regulation of biobanks in the Nordic countries in the context of the interaction of law and bioethics. The article analyzes the moral possibilities and legal boundaries of access to personal data by the state, society and the research community, provided that the inviolability of private life is strictly observed. On the basis of legislation of individual Nordic countries, as well as the regulatory framework of the European Union, the successes and difficulties in achieving the stated goal are discussed. The issues of opening, functioning and closing of biobanks, as well as the institutional, value and socio-cultural contexts of relevant practices are considered separately.
Systematization of the experience of legal regulation of innovation infrastructure in the CIS countries in the context of the protection and commercialization of RIA
Authors: Egorova M. A.
Published: October 2021

The innovation infrastructure as an object of legal regulation has not been sufficiently studied. The article summarizes the practice of improving legislation in the field of innovation in the countries of the Commonwealth of Independent States (CIS), which are leaders in innovative development — the Republic of Kazakhstan, the Republic of Belarus and the Republic of Armenia, which were determined on the basis of the human development index and the global innovation index. The regulatory framework of these CIS countries is considered from the position of state regulation of innovation and technological policy, the creation of technoparks, business incubators, venture organizations, technology transfer centers. The study revealed that the national innovation systems of the CIS countries have significant features. In the conclusions, it is noted that the legislative framework for the protection of the results of innovation activity is insufficiently systematized, fragmentary, and heterogeneously formed. On this aspect, broader interstate cooperation within the CIS is needed.
Euthanasia under French law
Authors: Haddadi A. , Ravaz F.
Published: October 2021

Under criminal law, euthanasia can have two distinct qualifications: that of homicide in the event that the act of directly killing another person is characterized, or that of assisting a third party in the suicide. These two qualifications are applicable on the condition that the agent — the author of the act of causing death — is not the one who went through it. In fact, selfeuthanasia is nothing more than suicide.

In addition to euthanasia imposed to a third party (such as in the case of Malevre, nurse from Mantes-la-Jolie, tried in 2003), the euthanasia requested and subscribed constitutes a complex legal question. Answering this question first involves specifying the position of contemporary criminal law in the face of suicide.

In the event that suicide is only decriminalized, in fact, the author of the act — regardless of the outcome of his actions, who is himself the victim, cannot be prosecuted. Nor ultimately receive any condemnation.

However, this lack of prosecution and conviction is by no means an endorsement of the act — suicide — by the law.

Moreover, in the event that suicide is a right, it would then be necessary to agree that any candidate for this act can request assistance in the accomplishment of his death. Given these two opposing approaches, imposed on us the question of whether there is a right to die.

Although the euthanasia imposed is unequivocally under ordinary criminal law, the euthanasia requested and granted is not based on any rights. To date, there is no right to approve a death request, but on the other hand, it does allow it to be respected and to some extent promotes its approach with dignity. This work will focus on two central points which are the possibility that euthanasia is a homicide under common law (I) and the attitude of French law concerning the right to death (II).
Comparative evaluation of the results of conservative and surgical methods of treatment of children with destructive forms of pyelonephritis
Authors: Kuzovleva Galina I. , Grushitskaya Elena V. , Staroverov Oleg V. , Rostovskaya Vera V. , Shmyrov Oleg S. , Zakharov Andrey I.
Published: October 2021

BACKGROUND: The relevance of destructive pyelonephritis in pediatric practice is determined by frequency of various complications of the disease associated with a high risk of irreversible morphofunctional changes in parenchyma of affected kidney, the lack of tactical consensus in the professional community and regulatory documents regulating the procedure for diagnostic and therapeutic support of this contingent of patients.
AIM: Substantiation of the tactics of effective treatment children with destructive pyelonephritis, based on the results of a multifactorial retrospective analysis of the course and outcomes of the disease.
MATERIALS AND METHODS: The results of the analysis of medical documentation of 38 patients with destructive pyelonephritis aged 3204 months (median 93.5) who received inpatient treatment in 20152019 in three specialized clinics in Moscow are presented.
RESULTS: More than half of the patients (28 children) in the acute period of the disease received conservative therapy, including infusion and antibacterial, the escalation of which was carried out with the preservation or increase of manifestations of the systemic inflammatory response syndrome, as well as negative dynamics according to ultrasound or CT data. In the group of patients (n = 10), indications for surgical treatment were formulated decapsulation of the kidney, opening of apostemas and abscessed foci, drainage of the paranephral space. During the examination in catamnesis, realized in 50%. It was found that in the majority (91%) of children treated conservatively, a statistically significant decrease in the volume of the kidney on the affected side was registered. These complications were not detected among the operated patients.
CONCLUSION: The pharmacy of choice for starting antibacterial therapy should be inhibitor-protected beta-lactams, carbapenems, if the etiological significance of staphylococcus is suspected, it is advisable to connect linezolid. In case of laboratory signs of hypercoagulation, it is necessary to connect anticoagulants. Surgical tactics can minimize the risk of complications associated with the purulent-destructive process, contributing to regenerative processes in the kidney parenchyma. The objectification of the results of the catamnestic examination is due to the performance of nephroscintigraphy.
Treatment of children with incomplete duodenal membrane
Authors: Nafikova Radmila A. , Gumerov Aitbai A. , Galimov Ildar I. , Neudachin Artem E.
Published: October 2021

BACKGRAUND: An incomplete or perforated duodenal membrane is a rare developmental pathology of the gastrointestinal tract.
AIM: This study aimed to analyze the diagnostic and treatment results of children with an incomplete duodenal membrane in the Republican Childrens Clinical Hospital in Ufa.
MATERIALS AND METHODS: This study retrospectively analyzed case histories of 34 children who underwent surgery for incomplete duodenal membrane from 2005 to 2020. Features of the life history of the children, clinical picture of the disease, presence of concomitant developmental anomalies, laboratory and instrumental examination data, surgical correction methods, and postoperative period were analyzed. All children underwent ultrasound examination of the abdominal organs and contrast-enhanced radiography of the upper gastrointestinal tract with barium sulfate. Esophagogastroduodenoscopy was performed in 17 cases.
RESULTS: Antenatally, the diagnosis was made in 21 cases. Patients age at the time of hospitalization was 9.7 2.7 days. Children were presented with symptoms such as persistent regurgitation or vomiting of curdled milk, which was sometimes mixed with bile (22 cases). Bloating in the epigastric region, retraction of the lower abdomen, and low weight gain after birth were found in nine children, and in five children, no weight changes were observed. Moreover, 13 (38.2%) children had concomitant developmental anomalies; 4 (11.7%) children had Down syndrome. Surgical treatment of 10 children was performed laparoscopically. Of the 24 children, three received laparotomic access, including conversion. The procedures included duodenotomy, partial excision of the membrane, and suturing of the duodenum. Enteral feeding was started 4.9 0.6 days after surgery. The average duration of hospitalization was 27 1.4 days.
CONCLUSION: Vomiting or frequent regurgitation in infants and low-weight gain should alert pediatricians and pediatric surgeons. Malformation of the duodenal membrane in combination with other malformations necessitates a comprehensive examination. Laparoscopic excision of the duodenal membrane is the preferred treatment.
Letter to the article “Sepsis in children: federal clinical guidelines (draft)”
Authors: Savin Ivan A.
Published: October 2021

In the letter, the author relies on data from the foreign and domestic literature and his own experience and confirms the relevant creation of clinical guidelines, Sepsis in children. The letter summarizes the main advantages of domestic recommendations and notes the provisions requiring critical assessment. In general, the author of the letter highly appreciated the work done by the authors of the recommendation.
Reply to the Commentary on the article “Sepsis in children: federal guidelines (draft)” I.А. Savin
Authors: Lekmanov Andrey U. , Popov Dmitry А.
Published: October 2021

The authors of the Clinical Guidelines are grateful to Professor I.A. Savin for his comments and provide answers to the comments made regarding the appointment of antibacterial drugs and immunoglobulins for sepsis in children.
Application Effect Analysis of Nursing Intervention in Stem Cell Therapy for Stroke Patients
Authors: Zhao Jing , Fu Lili , Zhu Juan , Liu Yan , Sun Xiaoqian
Published: October 2021

To study and analyze the actual clinical effect of nursing intervention in stem cell therapy for stroke patients. A total of 9 stroke patients treated with stem cell therapy in our hospital from September 2018 to September 2019 were selected as the research and analysis objects. All
patients were divided into observation group 5 stroke patients and control group 4 stroke patients by random number method. Both groups of patients were treated with stem cell therapy. Patients in the control group were treated with conventional nursing methods, and patients in the observation
group were treated with nursing intervention methods. The treatment compliance, psychological status, quality of life and daily living ability before and after intervention were compared between the two groups. There were no significant differences in exercise training, disease monitoring
and compliance with regular life between the two groups before intervention (P > 0.05), and the patients in observation group were significantly better than those in control group after intervention (P < 0.05), with significant differences. There was no significant difference in anxiety
and depression scores between the two groups before intervention (P > 0.05), and after intervention, the patients in the observation group were significantly lower than those in the control group (P < 0.05), and the difference was statistically significant. There was no significant difference
in quality of life and ability of daily living between the two groups before intervention (P > 0.05), and the patients in the observation group were significantly better than those in the control group after intervention (P < 0.05), the difference was statistically significant. The application
of nursing intervention in stem cell therapy for stroke patients has a significant effect, which significantly improves the patient's compliance with the treatment, alleviates the negative emotions of patients, improves the psychological status of patients, improves the quality of life and
daily living ability of patients, and is worthy of popularization and application in clinical nursing.
Coordination Between Tobacco Resource Development and Regional Economy
Authors: Xiang Qiulan , Zhang Chengmo
Published: October 2021

Objectives: This paper studies the relationship between the development of tobacco resources and the coordination of regional economy under the background of tobacco monopoly. Methods: This paper takes the institutional change theory as the theoretical fulcrum and the cost-benefit analysis
as the main line, the correlation between regional economy and the development of tobacco industry is compared. This paper expounds the evolution history and institutional characteristics of China's tobacco monopoly system, and analyzes the changes of production, supply and marketing relationship,
institutional characteristics and benefit distribution of the tobacco industry in each period. After the theoretical and empirical analysis of the costs and benefits of China's tobacco monopoly system, this paper studies the role of tobacco resource development in promoting regional economy
by comparing the costs and benefits of radical and gradual reform. Results: On the premise of retaining tobacco monopoly, we should take the separation of government and enterprises and the reform of tobacco fiscal and tax system as the breakthrough. This can change the tobacco industry from
administrative monopoly to economic monopoly and form tobacco trust. The linkage mechanism of "tax, profit and price" should be established to protect the interests of tobacco farmers. A tobacco auction center shall be established and a third-party tobacco rating agency shall be
guided. Conclusion: The net income of the new system is higher than that of the old system. The healthy development of tobacco industry can promote regional economy.
Integrated Theoretical Model of Smoking-Consumer Emotions and Research Outlook
Authors: Du Jiayi , Chen Xinkang
Published: October 2021

Objectives: Research on smoking-consumer emotions attracts increasing attention. Based on the literature review and analysis, this paper recognizes different definitions, categorizations, measurements of consumer emotions. Then the paper identifies the antecedent variables, moderating
variables and outcome variables of consumer emotion and relevant emotion theories to explain the relationship and proposes an integrated theoretical model of consumer emotions. Finally, this paper talks about the future studies of consumer emotions on four aspects. This paper offers insights
on the research of smoking-consumer emotions, theoretically and practically.
Tobacco Control Legal System Based on Environmental Protection Law Under the Background of Framework Convention on Tobacco Control
Authors: Liu Yang
Published: October 2021

Objectives: This paper studies the legal system of tobacco control based on environmental protection law under the background of the Framework Convention on tobacco control. Methods: Using the research methods of comparative analysis and literature analysis, and taking the tobacco control
law as the starting point, this paper expounds the development of global tobacco control civilization and the historical process of tobacco control at home and abroad. By analyzing the problems existing in the production, sales and consumption of tobacco products in China, we can trace the
source in the specific links of the life cycle of tobacco products. At the same time, this paper systematically analyzes the defects of China's tobacco control system in taxation and private rights, and summarizes the shortcomings of China's tobacco control system. Results: Many cities have
begun to try to enact non-smoking regulations to control smoking in public places. China's deficiencies in this regard are mainly due to the low level of relevant laws and regulations, which are basically local laws and administrative rules. The second is the problem of implementation, resulting
in the inadequate or virtual implementation of many laws. Conclusion: From the development trend of various countries, the view of respecting others' health rights and gradually banning smoking has gradually become everyone's consensus. The consolidation of this understanding needs the support
of laws to form a set of nonsmoking system with national laws as the core and administrative rules and local regulations as the supplement. Rights and responsibilities are clear, and rewards and punishments are based on evidence. Only in this way can we ensure to reduce the smoking rate, protect
everyone's health, and finally form a good atmosphere of no smoking and no respect for smoking in the whole society.
DESEMPENHO DA PRODUÇÃO DA CULTURA DE CANA-DE-AÇÚCAR NOS PRINCIPAIS ESTADOS PRODUTORES
Authors: Alves Lazaro Quintino , Franco Petrus Narciso , Zanetti Willian Aparecido Leoti , Góes Bruno César
Published: October 2021

O objetivo deste trabalho foi analisar o desempenho da área cultivada da cana-de-açúcar nos estados de São Paulo, Goiás, Minas Gerais e Mato Grosso do Sul. Os dados sobre a produção de cana foram coletados na base de dados da Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA) e Companhia Nacional de Abastecimento (CONAB), medidos em mil toneladas, entre 2000 e 2020. Os dados sobre produção de açúcar e etanol foram coletados na base de dados do Instituto Brasileiro de Geografia e Estatística (IBGE), medidos em mil hectares, entre 2005 e 2020. Para as análises estatísticas e elaboração gráfica, utilizou-se os softwares MINITAB 18® e SigmaPlot 14.0®. Para o teste medias utilizou-se a correlação de Pearson (r) com significância de 5% e 1%, para p-valor, 0,01 < p ≤ 0,05, e p ≤ 0,01. A expansão da cultura ocorreu em todas as regiões, destacando crescimento em Mato Grasso do Sul.
The elusive retromolar foramen and retromolar canal: A CBCT study
Authors: Pannalal Vijeta , Deoghare Abhijeet , Fating Chinar , Jha Satyendra
Published: October 2021

This study aims to evaluate the presence of retromolar foramen (RMF) and retromolar canal (RMC) in the mandible using cone beam computed tomography (CBCT) in Chhattishgarh population and to correlate its possible clinical impact.

175 CBCT images were collected from which 100 bilateral CBCT images of patients were retrospectively selected from the Department of Oral Medicine and Radiology of the Chhattishgarh Dental College and Research Institute and evaluated bilaterally which were taken for diagnostic purposes from maxillofacial radiology clinic and data were statistically analyzed. This was an observational descriptive study and all the images were processed and analyzed on CS3D imaging software.

The data was analyzed using chi square test.

The prevalence of RMF and RMC was observed in 8.5%, of which 10 were in females and 7 in males. The RMCs traversed in different directions – horizontal, vertical and angular. Based on the subjective assessment, each of these canals was further subclassified into straight and curved canal. In the present study in 12 of the cases angular curved type was found and in 3 cases, vertical straight was noticed. The bifurcation of the inferior alveolar nerve (IAN) canal was observed in 15% of the scans and remaining 85% had single mandibular canal. The proximity of RMF from buccal and lingual cortical plates was found buccally in 16 cases and in single case was found to be lingually.

Position of RMF might change with the presence and absence of third molar. The absence of third molar results in anteriorly located RMF. In majority of cases it was found that RMF was located more buccal than lingual. The parameters considered in the current study will guide the oral and maxillofacial surgeons while giving incisions in 3molar impacted cases, other pathologies and ease to preserve the retromolar foramen.
Hacia una educación 4.0: 10 módulos para la implementación de modelos híbridos
Authors: Arias Ortiz Elena , Dueñas Ximena , Elacqua Gregory , Giambruno Cecilia , Mateo-Berganza Díaz María Mercedes , Pérez Alfaro Marcelo
Published: October 2021

La presenta nota técnica busca contribuir a la implementación de modelos de educación híbrida en ALC desde una mirada práctica y anclada en el contexto regional. Para esto, se presenta un marco de implementación modular flexible, que posibilita la adaptación a las distintas realidades y contextos que conviven en la región. El cierre de escuelas generado por la COVID-19, la educación remota de emergencia, y el proceso de reapertura gradual, con la incorporación de modelos híbridos de emergencia, han tenido un efecto disruptivo en los sistemas educativos de toda la región. Para capitalizar las lecciones aprendidas durante la pandemia, y aprovechar el impulso de la digitalización acelerada para transformar la educación adaptándola a las necesidades del siglo XXI, es necesario ampliar la mirada hacia el mediano y largo plazo, y comenzar a sentar las bases para una transformación educativa en ALC. Los modelos de educación híbrida presentan grandes oportunidades para mejorar la calidad y equidad de los aprendizajes, acelerar los procesos de transformación digital educativa, e impulsar una educación 4.0, con un abordaje innovador, enfocado en habilidades, y adaptado a las necesidades y contextos de cada sistema educativo. El marco de implementación modular, estructurado en base a 10 módulos, invita a que cada país o sistema educativo pueda seleccionar y combinar aquellos módulos que mejor se adaptan a su contexto, elaborando su propia hoja de ruta para la educación híbrida.
ЩОДО ДОЦІЛЬНОСТІ ПОСИЛЕННЯ ДИСКРЕЦІЙНИХ ПОВНОВАЖЕНЬ НАЦІОНАЛЬНОГО БАНКУ УКРАЇНИ
Authors: Гудіма Т. , Чабан О.
Published: October 2021

Анотація. Проаналізовано функції Національного банку України і Банку Англії крізь призму викликів, що накладаються динамічним характером суспільства та процесами глобалізації. Висвітлено різний підхід України і Великобританії під час імплементації однакових положень Директиви (ЄС) 2015/2366 Європейського Парламенту і Ради від 25 листопада 2015 року про платіжні послуги на міжнародному ринку у внутрішнє законодавство.
Доводиться, що наявність необмежених дискреційних повноважень у центрального банку може завдати негативного впливу на стимулювання фінансової стабільності й одночасне забезпечення функції наглядового органу, зокрема на ринку платіжних послуг. Обґрунтовано, що замість цього збалансована система, яка складається з низки повністю або частково незалежних один від одного фінансових установ та органів влади, повинна взаємодіяти за зрозумілими і прозорими правилами.
Наголошується на невідповідності вітчизняних підходів правового регулювання діяльності центрального банку принципам, установленим європейськими вимогами, зокрема Директивою (ЄС) 2015/2366. Зокрема, законопроєкт «Про платіжні послуги» № 4364 від 12.11.2020 містить положення, які поєднують в особі Національного банку України повноваження регуляторного, наглядового органу та учасника ринку платіжних послуг. Крім того, широкі дискреційні повноваження центрального банку в Україні передбачають також деякі законодавчі функції. Зазначене не відповідає європейським принципам, правилу розподілу влади, несе загрози для фінансового ринку та фінансової стабільності країни в цілому.
На підставі досвіду Великобританії аргументовано доцільність розмежування наглядових і регуляторних функцій, зокрема на ринку платіжних послуг, між різними інституціями та забезпечення їхньої постійної взаємодії. Саме такий підхід здатен урівноважити вплив центрального банку та інших органів на шляху до сприяння фінансовій стабільності економіки країни.
Ключові слова: незалежність, платіжні послуги, дискреційні повноваження, імплементація, фінансова стабільність, нагляд, правове регулювання, європейські принципи.
Формул: 0; рис.: 0; табл.: 0; бібл.: 22.
ФІНАНСУВАННЯ ПРОЦЕСІВ ІНФОРМАТИЗАЦІЇ АДМІНІСТРАТИВНИХ ПОСЛУГ В ПУБЛІЧНОМУ СЕКТОРІ УКРАЇНИ
Authors: Мохова Ю. , Драган І. , Козирєва О. , Гавкалова Н. , Дубовик А.
Published: October 2021

Анотація. Досліджено механізми фінансування процесів інформатизації адміністративних послуг. Мета статті — визначити джерела фінансування i перспективи надання адміністративних послуг в умовах інформатизації публічного сектору України. Методи дослідження — порівняльний аналіз аналітичних та офіційних статистичних даних України, інститутів міжнародної підтримки на основі класифікації груп інструментів фінансування центрів надання адміністративних послуг (ЦНАП). Доведено, що децентралізація, розвиток i підвищення якості адміністративних послуг визначають ЦНАП пріоритетним напрямом реформування системи надання адміністративних послуг в Україні. Визначено правові засади створення i забезпечення функціонування ЦНАП, юридичні статуси установи, принципи процесу надання адміністративних послуг у ЦНАП. Проаналізовано динаміку кількості центрів надання адміністративних послуг i регіональні особливості функціонування. Виділено джерела фінансування центрів надання адміністративних послуг (державний бюджет, обласні та міські бюджети, кошти Державного фонду регіонального розвитку, міжнародні проєкти технічної допомоги). Доведено, що найпоширенішим і найбільшим джерелом фінансування процесів інформатизації в ЦНАП є державний бюджет (субвенція на розвиток інфраструктури). Запропоновано прогнозну модель створення і розвитку центрів надання адміністративних послуг в Україні за умов подальшого державного фінансування у відповідних обсягах. Обґрунтовано необхідність залучення зовнішніх джерел фінансування (коштів міжнародних проєктів технічної допомоги, ініціатив міжнародних донорів) в умовах обмеженості та дефіциту державного бюджету України. Обґрунтовано необхідність модернізації ЦНАП щодо використання IT-технологій. Виділено пріоритетні напрями комплексної реформи підвищення якості адміністративних послуг: децентралізація, спрощення, дерегуляція, розвиток інституційної спроможності і комунікаційна підтримка.
Ключові слова: фінансування, адміністративні послуги, інформатизація, публічний сектор.
Формул: 0; рис.: 4; табл.: 1; бібл.: 13.
КОНЦЕПЦІЯ РЕФОРМУВАННЯ КОРПОРАТИВНОГО ОПОДАТКУВАННЯ ДОХОДІВ В УКРАЇНІ
Authors: Мамонтова Н. , Витюк В.
Published: October 2021

Анотація. Досліджено доцільність та актуальність реформування корпоративного оподаткування доходів в Україні. Проаналізовано наукові розробки вітчизняних і закордонних науковців. Досліджено низьку фіскальну ефективність податку на прибуток підприємств і встановлено стійкий взаємозв’язок рівня сплати податків від комплексу додаткових чинників, а саме рівня корпоративного менеджменту, форми власності та уваги громадськості. Відзначено високу вагу сплати податку на прибуток у загальній структурі Топ-30 підприємствами України за сплати податків. Проаналізовано та узагальнено міжнародний досвід корпоративного оподаткування доходів. Обґрунтовано необхідність заміни податку на прибуток на інший вид податку корпоративного оподаткування доходів. Зазначено системні проблеми щодо ефективності наявних у світі моделей корпоративного оподаткування доходів. Підкреслено негативний вплив низькоподаткових юрисдикцій на функціонування податкових систем низки країн і створення ефекту нерівномірності податкового навантаження. Систематизовано інформацію щодо практичного досвіду впровадження податку на виведений капітал у країнах світу. Досліджено низьку ефективність такої концепції реформування корпоративного оподаткування і недоцільність використання цієї концепції в сучасних умовах України. Оцінено можливість заміни податку на додану вартість і встановлено критичну залежність доходів зведеного бюджету України від надходжень цього податку на рівні більше ніж 35 %. Розроблено та обґрунтовано концепцію реформування корпоративного оподаткування доходів шляхом упровадження 1 % податку з обороту в доповнення податку на додану вартість і повної відміни податку на прибуток. Оцінено обсяг надходжень податкових надходжень за 2010—2019 рр. у разі впровадження авторської концепції корпоративного оподаткування доходів у порівнянні з актуальною системою оподаткування. Згруповано і систематизовано позитивні наслідки для економіки України внаслідок зміни системи корпоративного оподаткування доходів. Підкреслено необхідність формування нової податкової культури і філософії взаємодії представників податкових органів та бізнесу.
Ключові слова: корпоративне оподаткування доходів, податок на прибуток підприємств, податок на виведений капітал, податок з обороту.
Формул: 0; рис.: 0; табл.: 3; бібл.: 19.