bluuebunny/crossref_metadata_2025 huggingface dataset:
Algılanan Yönetici Desteğinin Çalışan Performansına Etkisinde Örgütsel Özdeşleşmenin Rolü
Authors: ÜLBEĞİ İlksun Didem , DAĞTEKİN Hasan , YALÇIN Azmi
Published: October 2021

Günümüzde artan rekabet ortamında işletmelerin, rakiplerine karşı üstünlük elde edebilmek adına ortaya koyacağı çabada çalışan performansının önemi oldukça büyüktür. İşletmeler, çalışan performansını arttırabilmek için çeşitli yollara başvurmaktadır. Yönetici desteği ise çalışan performansının artmasında önemli bir değişken olarak karşımıza çıkmaktadır. Bunun yanı sıra çalışanların örgütsel özdeşleşme düzeyi, gösterecekleri performansa doğrudan etki etmektedir. Örgütsel özdeşleşme olmadan yalnızca yönetici desteği çalışan performansını etkilemekte midir? Yoksa yönetici desteğinin çalışan performansına etkisinde, örgütsel özdeşleşmenin aracılık rolü mü bulunmaktadır sorusu merak edilen bir konu olarak bu çalışmanın amacını oluşturmaktadır. Bu çalışma kapsamında 217 banka çalışanından kolayda örnekleme yöntemiyle veri toplanmıştır. Toplanan veriler ışığında yapılan analizler neticesinde bu çalışmada öne sürülen hipotezler desteklenmiş ve algılanan yönetici desteğinin çalışan performansına etkisinde örgütsel özdeşleşmenin aracı bir rol oynadığı görülmüştür.
Dense Hyperthermic Intraperitoneal Chemotherapy with Cisplatin in Patients with Stage III Serous Epithelial Ovarian Cancer: A Retrospective Study
Authors: He Xiaoli , Wei Li , Li Rui , Jing Shuang , Jia Linlin , Ji Danwei , Li Yali , Wang Yue , Zhu Yongxia
Published: October 2021

Background: To investigate the efficacy and safety of interval debulking surgery (IDS) combined with dense hyperthermic intraperitoneal chemotherapy (HIPEC) with cisplatin in Chinese patients with FIGO stage III serous epithelial ovarian cancer (EOC).Methods: This retrospective single-center study reviewed the demographic and clinical data of 197 patients with primary FIGO stage III serous EOC who were treated with IDS with (n=121) or without (n=76, control group) dense HIPEC between January 2012 and April 2017. The co-primary endpoints were progression-free survival (PFS) and overall survival (OS), and the secondary endpoint was the occurrence of adverse events.Results: The median PFS was 24 months in the IDS plus dense HIPEC group, whereas it was 19 months in the IDS alone group (hazard ratio [HR] 0.46, 95% confidence interval [CI]: 0.33-0.65, p=0.000). The median OS in patients treated with IDS plus dense HIPEC (51 months) was significantly longer than that in patients treated with IDS alone (40 months, HR 0.52, 95% CI: 0.35-0.78, p=0.001). The demographic and preoperative clinical characteristics of these two groups were comparable (p>0.05). In the IDS alone group, no adverse events were recorded in 42 (55.3%) of the 76 patients, and 14 (18.4%) patients were reported to have grade III/IV adverse events. In the IDS plus dense HIPEC group, no adverse events were recorded in 55 (45.5%) of the 121 patients, and 23 (19.0%) patients were reported to have grade III/IV adverse events. No postoperative deaths occurred within 30 days in either group and neither did severe fatal complications in the IDS plus dense HIPEC group.Conclusions: IDS plus dense HIPEC with cisplatin in Chinese patients with FIGO stage III serous EOC is associated with improved survival and is reasonably well tolerated by patients.
Can Online Learning Fulfill the Competence of Medical Study Program Students?
Authors: Sundari Sri , Purbohadi Dwijoko , Khotibudin Muh
Published: October 2021

Background: The Covid-19 outbreak has had a huge impact on education, especially in health education both throughout the world and in Indonesia. Educational institutions are forced to close any access of offline meeting in order to reduce the spread of Covid-19. This is in accordance with the Official Letter of Ministry of Education and Culture Republic of Indonesia. No. 36962 / MPK.A / HK / 2020, the government prohibits universities from holding offline lectures then encourages online learning. Online learning in Indonesia is not popular before pandemic but it must be held. However, the learning goal must still be achieved. The learning process is aimed to achieve the expected performance also improve the quality of education. Quality assurance and personalized online learning are one of the mechanisms that help higher education to achieve planned outcomes. Online learning changes all aspects in the learning process. Both educators and students need to adapt to the online learning process. As a result, students and educators need to adapt quickly to minimize the material backlog. Due to the various reasons above, it is necessary to develop an online learning model that can help the learning process both in the cognitive and psychomotor domains in the Medical Study Program so that the expected competencies can still be achieved. Method: The data was analyzed by using t-test statistic to compare between students’ achievement in distance learning and offline learning.Results: The results showed that the learning outcomes of students who took online learning methods were higher than those of students who took offline learning. This can be seen from the average learning evaluation score, the number of passing practicum scores, the number of passing skills lab scores and the number of passing blocks (p<0.05). Conclusion: It can be concluded that online learning helps students achieve competence at the academic stage of learning.
Investigation of Biodesulfurization by A Novel Pseudomonas Strain and the Underlying Metabolic Mechanisms
Authors: Wei Dong , Liu Li , Shi Jiping , Yan Weizhi , Chen Xiaojia , Li Xiang
Published: October 2021

The increasing public expectations for good air quality have necessitated the development of biodeodorization technology. In this study, a novel heterotrophic Pseudomonas strain was isolated from biogas slurry and its biodesulfurization ability was investigated. The optimization of culture conditions determined 30 ℃ and 200 rpm as the optimal temperature and shaking speed. Under such conditions, 50 mM thiosulfate was completely consumed. The whole genome sequencing and functional annotation identified the genes associated with sulfur metabolism and the RT-qPCR analysis quantified the expression level of corresponding genes. The results showed that this strain was able to convert thiosulfate to sulfane, which could be decomposed into elemental sulfur and therefore achieved desulfurization. However, this process was relatively weak as most thiosulfate was converted into soluble tetrationate catalyzed by gene tsdA. Further research would focus on the enhancement of sulflane production pathway through metabolic engineering tools.
Effects of Vaccine Health and Safety Perceptions on COVID-19 Vaccine Uptake in Ghana: Implications for Implementing Rollout Programs
Authors: Aram Simon Appah , Hagan John Elvis , Mansoh George Kweku Afriyie , Saalidong Benjamin M. , Lartey Patrick Osei , Ahinkorah Bright Opoku , Seidu Abdul-Aziz , Ameyaw Edward Kwabena , Appiah Augustine , Hotor Divine Worlanyor , Gyimah Justice
Published: October 2021

Background A major component of rolled-out COVID-19 pandemic response and preparedness is the administration of vaccines. Globally, resistance towards vaccination programs are well known and documented. This study sought to evaluate the effects of general vaccine health perceptions and the confidence in COVID-19 vaccine safety towards uptake in Ghana. MethodsA cross sectional online survey involving 620 Ghanaians was conducted. The data was subjected to both descriptive (frequency, percentages, and chi-square tests) and inferential (nested binary logistic regression) analyses. Results The preliminary findings showed that 80.32% of participants believed that vaccines were healthy and 73.06% had confidence in a COVID-19 vaccine safety, although 81.19% of the respondents were particularly concerned about the source of the vaccine. Other evidence revealed that 78.55% and 71.45% of respondents indicated their willingness for mandatory and voluntary COVID-19 vaccine uptake or shot respectively. In all operationalized regression models, Ghanaians who believed that vaccines are healthy and those who had confidence in a COVID-19 vaccine safety were more likely to take a mandatory or voluntary COVID-19 vaccine compared to those who thought and believed otherwise. ConclusionIndividual preferences and/or intentions toward COVID-19 vaccine uptake and uptake route (i.e., mandatory, voluntary) were influenced by multifaceted determinants: biosocial (age, marital status, education), socio-cultural (religion) and contextual (geographical zone, source of vaccine as a concern) factors. To consolidate and possibly increase vaccine uptake in response to the COVID-19 pandemic in Ghana, health education and promotion programs should aim at creating awareness on the benefits of vaccine uptake while addressing the health and safety concerns on the potential side effects through evidence-based community messaging from credible sources. It is important to show speciﬁc commitment to transparency and reliable information to build public trust by decision-makers.
Nurses’ Perceptions of Continuing Professional Development: a Qualitative Study
Authors: Yu Xiaoyan , Huang Yi , Liu Yu
Published: October 2021

Background: Continuing professional development is regarded as one of the important approaches to maintaining skills and motivation for work. However, there is a lack of qualitative studies to explore Chinese nurses’ continuing professional development. The study aims to explore Chinese nurses’ perceptions of continuing professional development and challenges they face. Methods: The study was conducted in a tertiary hospital located in the central region of China from July to August 2020. Purposive sampling was used to recruit 14 nurses and face to face semi-structured interviews were conducted from July to August 2020. Then the recorded data were analysed and collated according to the thematic analysis. This study followed the consolidated criteria for reporting qualitative research (COREQ). Results: Four themes were extracted: improving specialty ability; different development phases; the importance of personal effort; the obstacle of work-family conflict.Conclusions: This study contributed to our understandings of nurses’ continuing professional development. Nurses held a positive attitude towards continuing professional development and they faced challenges in the meantime. Special attention and targeted supports should be provided to promote the continuing professional development of nursing staff.
Epigenetic Mechanism and Survival Prognosis Analysis of Serum Exosomes from Ovarian Cancer Patients based on Sequencing Technology and Bioinformatics
Authors: Xia Li , He Huang
Published: October 2021

Backguound: To screen the signaling axis of epigenetic modification in serum exosomes of ovarian cancer patients based on sequencing technology and raw signal analysis, in depth study of the potential mechanism of action of ovarian cancer, prediction of potential therapeutic targets and survival prognosis analysis of potential targets.Methods: Serum exosomes from three ovarian cancer patients were selected as the experimental group, and serum exosomes from three uterine fibroid patients as the control group, and whole transcriptome of serum exosomes was performed to obtain differentially expressed lncRNA and mRNA in ovarian cancer,The miRcode database and miRNA target gene prediction website were used to predict the target genes, Cytoscape software was used to draw a ceRNA network model of epigenetic modification of ovarian cancer serum exosomes, and the R language was used for GO and KEGG enrichment analysis of the target genes. Finally, the TCGA website was used to download clinical and expression data related to ovarian cancer, and the common potential target genes obtained in the previous period were analyzed for survival。Results: A total of 117 differentially expressed lncRNAs as well as 513 differentially expressed mRNAs (P < 0.05, |log2 FC|≥ 1.0) were obtained by combining sequencing data and raw signal analysis, and 841 predicted target genes were reciprocally mapped by combining mircode database and miRNA target gene prediction website, resulting in 11 potential target genes related to ovarian cancer (FGFR3, BMPR1B, TRIM29, FBN2, PAPPA, CCDC58, IGSF3, FBXO10, GPAM, HOXA10, LHFPL4), and survival prognosis analysis of the above 11 target genes revealed that the survival curve was statistically significant (P < 0.05) for HOXA10 only genes, but not for the other genes, and through enrichment analysis, we found that the above target genes were mainly involved in biological processes such as regulation of transmembrane receptor protein kinase activity, structural molecule activity with elasticity, transforming growth factor - activated receptor activity, and GABA receptor binding, and were mainly enriched in signaling pathways regulating stem cell pluripotency, bladder cancer, glycerolipid metabolism, central carbon metabolism of cancer, tyrosine stimulation to EGFR in signaling pathways such as resistance to enzyme inhibitors.Conclusions: The serum exosomal DIO3OS-hsa-miR-27a-3p-HOXA10 epigenetic modification signaling axis affects ovarian cancer development and disease survival prognosis by targeting transcriptional dysregulation pathways in cancer.
FUS Mutation Causes Lipid Metabolism Disorder in Skeletal Muscle Associated With ALS
Authors: Zhou Binbin , Li Xiaobing , Zheng Yilei , Dong Huifang , Yu Jiaxi , Zou Yang , Zhu Min , Yu Yanyan , Fang Xin , Zhou Meihong , Zhang Wei , Yuan Yun , Wang Zhaoxia , Deng Jianwen , Hong Daojun
Published: October 2021

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, characterized by the dysfunction of upper and lower motor neurons accompanied by muscle weakness and wasting. Recently, several studies on ALS patients and animal models implicated muscle intrinsic toxicity played a role in the disease progression with uncertain mechanisms. In this study, we explored the possible disorder of lipid metabolism in myocytes associated with ALS. Initially, skeletal muscle from 41 ALS patients as well as 53 non-ALS control subjects were investigated, and identified that the accumulation of lipid droplets in the muscle fibers of ALS patients was significantly increased, especially in the patients with FUS mutations. A myoblasts (C2C12) cell model expressing FUS-K510Q mutant induced the accumulation of lipid droplets and mitochondrial dysfunction. Consistently, transgenic flies expressing FUS-K510Q under a muscle-specific driver showed elevated triglyceride levels in flight muscle, as well as locomotor defects. Biochemical analysis of C2C12 cells and fly muscle tissues showed up-regulation of PLIN2, and down-regulation of ATGL and CPT1A, indicating inhibition of lipolysis and fatty acid β-oxidation in muscle cells with FUS mutations. Our study provided a potential explanation for the lipid droplets accumulation in skeletal muscle of ALS. Our data also suggested that lipid metabolism disorder and mitochondrial dysfunction play a crucial role in the muscle intrinsic toxicity of ALS.
Unraveling MicroRNA Mediated Gene Regulation in Centella Asiatica (L.) Urb. by High-Throughput Sequencing based Small-RNA Profiling.
Authors: Ranjith Gouri Priya , Satheesan Jisha , Sabu K K
Published: October 2021

Centella asiatica is a widely spread herb mostly found in the tropics having extensive medicinal values. Here, we report for the first time, transcriptome-wide characterization of miRNA profile from the leaves of C. asiatica using high-throughput Illumina sequencing. We identified 227 conserved and 109 putative novel miRNAs. Computational screening revealed potential mRNA targets for both the conserved and novel miRNAs encoding diverse transcription factors and enzymes involved in plant development, disease resistance, metabolic and signaling pathways. Gene ontology annotation and KEGG analysis revealed the miRNA targets to be involved in a wide range of metabolomic and regulatory pathways. The differential expression of the miRNA encoding genes in diverse tissues was determined by real-time PCR analysis. We also found that gene expression levels of miR156, 159 and 1171 was reduced in salicylic acid treated axenic shoot cultures of C. asiatica compared to its control. Furthermore, RLM-RACE experiments mapped miRNA-mediated cleavage at two of the mRNA targets. The present study represents the large-scale identification of microRNAs from C. asiatica and contributes to the base for the up-coming studies on miRNA-mediated gene regulation of plant secondary metabolite pathways in particular.
Impact of the Gamma Variant on the ICU Admission in a Hospital of the Autonomous City of Buenos Aires (Caba), Argentina
Authors: Mandich Veronica , Chiacchiara Daniel , Bravo Marcelo , Pilipec Antonio , Grimaldi Santiago , Cotez Johnny , Paniouk Victor , Arevalo Henry , Escobar Oswaldo , Flach Sebastian Perez , Pozo Amilcar Herbas , Aimar Alejandro
Published: October 2021

Purpose

Comparison between patients admitted to the Intensive Care Unit (ICU) with ventilatory support during the first and second wave (Gamma variant) of COVID 19 in a tertiary hospital in the City of Buenos Aires.
Method

Descriptive, observational, prospective cohort study in ICU of an acute general hospital in Argentina, with patients adult patients COVID-19 admitted consecutively to the ICU. The ICU the main variables of interest: Demographic and laboratory data, history, duration of MV, mortality.
Results

44 patients were recruited during the first wave, and 80 in the second. Significant differences were observed in the second wave for age (60, [SD 11]; vs 68 [SD 11]; p <0.01), days with symptoms (9 [SD 5]; vs 4.5 [SD 3]; p <0.01), duration of MV (10 days [SD 7]; vs 16 [SD 13]; p <0.01), Ferritin (1450 mcg / l [SD 547]; vs 941 mcg / l [ SD 593]; p 0.04) and use of antibiotics (97% vs 45% p <0.01). There was no difference in mortality (66% vs 78% p 0.14) but there was in its primary causes; being more frequent hypoxemia associated with sepsis in the second wave (40% vs 3.4% p <0.01) and hypoxemia and multiorgan failure in the first (28% vs 4% p <0.01).
Conclusions

During the second wave of the pandemic, due to Gamma variant, more patients were admitted to our unit, younger, with a longer evolution time, a shorter time on MV and a greater inflammatory response, with no difference in mortality, although there was a difference in its causes.
Diode Pumped Alkali Laser - Current Status and Prospects
Authors: Endo Masamori , Nagaoka Hiroki , Wani Fumio
Published: October 2021

The historical aspect, present status, and future prospects of diode-pumped alkali lasers (DPAL) are discussed. DPAL is a relatively new laser, first reported in 2003. It is characterized by extremely high scalability, good beam quality by virtue of its gaseous laser medium, and intrinsically high efficiency because it is a three-level laser with a small Stokes defect. Because of these features, DPAL is being studied as a directed energy weapon and is also expected to find applications in industry and space. We propose the use of DPAL for space debris removal. Some of the research results of our group are also introduced.
An overview of hybrid random number generators
Authors: Cornaciu Veronica
Published: October 2021

The generation of random numbers is a important topic in cryptography. Random number generators are bradly divided into two categories: random number generators(RNGs) and pseudo-random number generators(PRNGs). If the PRNGs werw intensively studied in the specialized literature, many such generators being built and analyzed, the topic of RNGs did not capture the researchers atention so much. Candidates in this first category generate nondeterministic sequences and are often based on physical reactions, such as radioactive degradation or mouse movement. A special category of generators is the one that combines the two categories, namely, the category of hybrid generators (HRGs). The purpose of this paper is to study in detail the category of hybrid generators and to provide a detailed analysis of the results of statistical tests, security , portability and how to improve some of the generators of this category.
Study of social engineering attacks in Romania 2019
Authors: Moinescu Radu
Published: October 2021

Social engineering is one of the biggest challenges facing network security because it exploits the natural human tendency to trust. In recent years, cybercriminals have done everything in their power to be innovative. They are taking advantage of every aspect of our lives to develop new social engineering schemes. This paper provides an in-depth survey about the social engineering attacks that took place in Romania in 2019, their classifications, detection strategies, and prevention procedures.
Social-cognition and dog-human interactions: Is there potential for therapeutic-interventions for the disability sector?
Authors: Bellio M. , Silveira S.
Published: October 2021

The notion that dog-human interactions have the potential to mitigate impacts concerning the delay of typical development of social skills in humans is a novel concept. Research evidence concerning three aspects of social-cognition: sensory perception of social-cues, theory of mind and learning social-schemas, were reviewed with the scope to explore this notion. Literature from two different fields of research inquiry: animal-behaviour and neuroscience, was evaluated. Emerging from the animal-behavioural studies’ review was that aspects of dog behaviour could be a functional analogue of human behaviour (e.g. perception of social-cues). Neuroscience research theories concerning the functional role of the mirror neuron system in social-cognition in humans were evaluated against evidence from animal-behavioural studies investigating the relationship between dogs and children with socio-communicative developmental delays (e.g. vision impairment, Autism). It emerged that both fields of research suggested that through “embodied simulations” an alternative (e.g. to language and/or vision) approach to acquiring knowledge concerning the world of social interactions may be possible for individuals who present with developmental delays of social-competence. Within this context it is suggested that dog-human interactions may provide learning opportunities for development of social-competence in individuals with vision impairment. Implications for practice for the disability sector and specific examples for professionals who work with individuals who have vision impairment and assistance/therapy dogs are discussed.
Sufism and Interreligious Dialogue: The Naqshbandi Haqqani Sufi Order in Indonesia
Authors: Nugroho Wahyu
Published: October 2021

Sufism plays a vital role in the process of spreading Islam in Indonesia, the key factor being inclusion and tolerance. Nowadays, the tolerant spirit of Sufi Islam is more and more challenged by certain intolerant Salafi groups. It seems that some Sufi groups in Indonesia have unfortunately adopted some of their attitudes and have become increasingly wary of other religions and unwilling to engage with them in a constructive dialogue. This negative trend creates tension within the Muslim community and in Indonesian society at large. After all, Indonesia is a country that is built on the principles of religious plurality. This article explores the teachings and practices of the Naqshbandi Haqqani Sufi order and their understanding of religious plurality. The study found that—despite the existing Salafi trend— the Naqshbandi shaykhs continue to praise religious plurality as one of God’s blessings. In their view, the sincere engagement in interreligious dialogue allows their followers to experience and actualize God’s Love. The Naqshbandi order also actively engages in interreligious dialogue with other communities in Jakarta and Kartasura.
Repurposing Drugs as Novel Triple-negative Breast Cancer Therapeutics
Authors: Das Amiya , Agarwal Pallavi , Jain Gaurav Kumar , Aggarwal Geeta , Lather Viney , Pandita Deepti
Published: October 2021

Background:

Among all the types of breast cancer (BC), triple negative breast cancer (TNBC) is the most aggressive form having high metastasis and recurrence rate with limited treatment options. Conventional treatments such as chemotherapy and radiotherapy have lots of toxic side effects and also no FDA approved therapies are available till now. Repurposing of old clinically approved drugs towards various targets of TNBC is the new approach with lesser side effects and also leads to successful inexpensive drug development with less time consuming. Medicinal plants containg various phytoconstituents (flavonoids, alkaloids, phenols, essential oils, tanins, glycosides, lactones) plays very crucial role in combating various types of diseases and used in drug development process because of having lesser side effects.

Objective:

The present review focuses in summarization of various categories of repurposed drugs against multitarget of TNBC and also summarizes the phytochemical categories that targets TNBC singly or in combination with synthetic old drugs.

Methods:

Literature information was collected from various databases such as Pubmed, Web of Science, Scopus and Medline to understand and clarify the role and mechanism of repurposed synthetic drugs and phytoconstituents aginst TNBC by using keywords like “breast cancer”, “repurposed drugs”, “TNBC” and “phytoconstituents”.

Results:

Various repurposed drugs and phytochemicals targeting different signaling pathways that exerts their cytotoxic activities on TNBC cells ultimately leads to apoptosis of cells and also lowers the recurrence rate and stops the metastasis process.

Conclusion:

Inhibitory effects seen in different levels, which provides information and evidences to researchers towards drug developments process and thus further more investigations and researches need to be taken to get the better therapeutic treatment options against TNBC.
Paisagens Culturais e Património da Mafalala: A Casa de Eusébio
Authors: Aminagi Dulámito Ardichir
Published: October 2021

No decurso das actividades de inventariação do Património Cultural Imaterial (PCI), no Bairro da Mafalala, realizado pelo ARPAC (Instituto de Investigação Sócio Cultural), em agosto de 2016, no âmbito da implementação da convenção da Organização das Nações Unidas para a Educação, a Ciência e a Cultura (Unesco) de 2003, e defronte da casa de Eusébio ou ruínas desta, fomos interpelados por um indivíduo, identificado como guarda do local, que nos proibiu de tirar imagens, quer fílmicas, assim como fotográficas, alegadamente, porque não tínhamos autorização para tal. Isto impeliu-nos, por um lado, a tentar perceber como é que aquele lugar, em ruínas, era designado património e estruturava a memória colectiva do bairro. Quer dizer, compreender esta capacidade da memória de transitar gerações sem uma existência concreta que objectifique sentido e simbologia do lugar, ou seja, como é que “lugares abstractos” alimentam a memória e história da Mafalala. E, por outro, e alicerçando-nos nas perspectivas culturais de Geertz (1973) e de Crane (1994), como organização de padrões com dimensões simbólicas, ambas elencadas na memória, como elemento crucial de constituição de todos processos sociais, procura-se perceber e compreender a casa de Eusébio como um suporte e veículo de uma memória flutuante.
Estudo Longitudinal da Adequabilidade da Estrutura Organizacional ao Negócio: O Caso da Petromoc, SA
Authors: Manjate José Francisco Marcos , Silva J. M. Vilas-Boas da
Published: October 2021

O tema enquadra-se no tópico “mobilidade, tecnologias e vida contemporânea”. Endereça a discussão da adequabilidade da estrutura organizacional ao negócio, focando-se nos sistemas de informação (SI), delimitados à cadeia de abastecimento (CA). Liga-se ao tópico umbrela porque a CA permite a organizações independentes alinhar e coordenar actividades internas e criar relações de negócios. A situação-problema concerne à implementação de SI dos processos internos de negócio e a ligação destes aos sistemas homólogos dos fornecedores e clientes para ganhar vantagem competitiva à concorrência. A soft systems methodology (SSM) foi operacionalizada através de um estudo de caso na empresa Petróleos de Moçambique, tendo como unidades de análise o negócio, a estrutura e os SI. O resultado é uma lista de actividades correspondendo a alternativas desejáveis para melhorar a situação-problema. Esperam-se as seguintes contribuições: para a prática, uma lista de mudanças a efectuar no caso; para a teoria, uma representação mais defensável do que outras quanto à consistência e adequação dada pela validação do modelo; para a investigação, a operacionalização da SSM como metodologia credível. Como critérios de verificação da qualidade da pesquisa, têm-se a relevância do modelo e a competência na sua concepção.
O Turismo Como Experiência e Como Desejo de Território e de Viagem
Authors: Martins Moisés de Lemos
Published: October 2021

O ponto de vista que vou desenvolver sobre o turismo não se prende com uma análise económica, nem sequer com uma análise política stricto sensu. Vou configurar o turismo como uma atividade cultural. Por esta razão, o ponto de vista que vou desenvolver sobre o turismo é fenomenológico e sócio-antropológico. Não vou refletir, pois, sobre o negócio (nec/otium — não/lazer; atividade, trabalho, comércio), mas sobretudo sobre ócio (otium — tempo livre de atividade).
Um “Turismo Literário”: Percursos Africanos Pela Literatura
Authors: Saraiva Sueli da Silva
Published: October 2021

Entre as várias motivações que levam uma pessoa a viajar, talvez a mais nobre seja a de refazer ou percorrer caminhos imortalizados por obras literárias e, mais recentemente, cinematográficas. O continente africano é pródigo na produção de um fértil imaginário de viajantes, desde os aventureiros e exploradores de séculos passados, aos turistas contemporâneos. Dois enredos literários potencializam a construção de imagens e narrativas moçambicanas e angolanas, pela via do romance, descrevendo árduos processos de mudanças políticas e sociais enquanto revelam caminhos para uma inestimável revelação cultural. Apresentam-se nos textos, os espaços e paisagens literários da fantástica viagem de trem pelo interior de Angola, em Mãe Materno Mar, de Boaventura Cardoso (2001), e a maravilhosa travessia do rio para a fictícia ilha Luar-do-Chão de Um Rio Chamado Tempo, uma Casa Chamada Terra, de Mia Couto (2003). São obras em que o deslocamento se faz por paisagens poéticas, revelando horizontes geográficos, sociais e humanos que a experiência literária pode despertar.
Спиральное магнитное упорядочение и переход металл--диэлектрик в модели Хаббарда на треугольной решeтке
Authors: Гильмутдинов В.Ф. , Тимиргазин М.А. , Аржников А.К.
Published: October 2021

The magnetic phase diagrams of the two-dimensional Hubbard model for isotropic and anisotropic triangular lattices are constructed within the Hartree-Fock and slave boson approximations. The triangular lattice specific non-collinear and spiral magnetic states, as well as phase separation between them, are shown to be realized in a wide range of model parameters along with collinear magnetic states (stripe antiferromagnetic and ferromagnetic). Phase transitions of the first and second order are found, and the boundaries of the phase separation regions are determined.
A comparison of the two approximations, Hartree-Fock and slave boson, shows that electronic correlations suppress magnetic states, the region of paramagnetism being expand, for values U/t>5. At the same time, when the Fermi level is near the van Hove singularity, electron correlations do not change the diagrams qualitatively, which is consistent with the previously obtained result for square and cubic lattices. The results are compared with the data available in the literature for other methods and approaches.
Current experience in the use of amino acid-based formula in children
Authors: Nyankovskyy S.L. , Nyankovska О.S. , Yatsula M.S. , Horodylovska M.I.
Published: October 2021

Amino acid-based formulas (AAFs) are similar to most other infant kinds of milk except for one important difference. Instead of containing whole or broken down cow’s milk protein, they contain amino acids. These individual amino acids are so small that they are not recognised by the immune system as allergens and do not provoke any allergic reaction in children with cow’s milk allergy. In recent studies, AAFs were well tolerated and supported growth in otherwise healthy infants without cow’s milk protein allergy, and in those with cow’s milk protein allergy. Short bowel syndrome, a disorder characterized by diarrhea, malabsorption, fluid and electrolyte disturbances, and eventually malnutrition, is usually caused by massive intestinal resection. Even though the causes of short bowel syndrome are diverse, the management has identical pillars: parenteral nutrition and early enteral nutrition. Enteral nutrition remains an important and controllable factor. The direct trophic effect of nutrients and stimulation of gastrointestinal secretions and hormonal factors enhances intestinal adaptation. AAFs promote rapid weaning of parenteral nutrition after the introduction of an elemental formula. Besides, studies show that they reduce intestinal inflammation (the level of fecal calprotectin).
Hematological manifestations of trichobezoar in a child
Authors: Nykytyuk S.O. , Bodnarchuk R.V. , Boyarchuk O.R. , Levenets S.S. , Dolynna M.V.
Published: October 2021

Background. Trichobezoar is a dense compound in the human stomach, consisting of swallowed hair, food particles, and gastric mucus. Sometimes it passes into the initial part of the small intestine. Its clinical picture is very similar to that of a tumor, so it is necessary to conduct a thorough diagnosis. Materials and methods. The article deals with a case of severe protein-vitamin-iron deficiency anemia in a 5-year-old girl on the background of trichobezoar. Results. The child’s condition is severe due to the clinical picture of iron-protein-deficiency anemia of a very severe degree. During her stay in the hospital, the girl’s condition deteriorated sharply due to the rapid increase in weakness and pallor of the skin, anasarca. Due to the critical growth of the anemic syndrome, the question of the need for blood transfusion and further surgery arose. Conclusions. The peculiarity of this case is a critical increase in anemia in the absence of classic signs of hemolysis on the background of chronic eating and psychosomatic disorders. Thus, it is necessary to form vigilance in pediatricians to trichobezoar and increase the level of knowledge about the correct diagnostic algorithm in such cases.
Estimating the risk of thrombotic events in people with congenital hemophilia A using US claims data
Authors: Faghmous Imi , Nissen Francis , Kuebler Peter , Flores Carlos , Patel Anisha M , Pipe Steven W
Published: October 2021

Aim:Compare thrombotic risk in people with congenital hemophilia A (PwcHA) to the general non-hemophilia A (HA) population.Patients & methods:US claims databases were analyzed to identify PwcHA. Incidence rates of myocardial infarction, pulmonary embolism, ischemic stroke, deep vein thrombosis and device-related thrombosis were compared with a matched cohort without HA.Results:Over 3490 PwcHA were identified and 16,380 individuals matched. PwcHA had a similar incidence of myocardial infarction and pulmonary embolism compared with the non-HA population, but a slightly higher incidence of ischemic stroke and deep vein thrombosis. The incidence of device-related thrombosis was significantly higher in PwcHA.Conclusion:This analysis suggests that PwcHA are not protected against thrombosis, and provides context to evaluate thrombotic risk of HA treatments.
Olhando a dimensão epistemológica da organização do conhecimento brasileira com três lentes da análise de domínio: epistemológica, estruturação científica e terminológica
Authors: Alencar Maíra Fernandes , Cervantes Brígida Maria Nogueira
Published: October 2021

Considerando la importancia de una comunidad científica internacional para el cultivo de las reflexiones e investigaciones, seleccionamos para ser mapeada la ISKO-Brasil. El objetivo del estudio es presentar un mapa de los trabajos que se presentaron en la dimensión epistemológica. La metodología utilizada fue el análisis de contenido para la categorización y el análisis de dominio con tres estudios de enfoque: 1) Epistemológico - para identificar los temas de investigación; 2) Estructura de la comunicación científica - cuyo enfoque es describir el año, los autores y las instituciones, y finalmente 3) Estudios terminológicos, mediante la extracción de términos representativos de los títulos de las publicaciones, para categorizar y comparar con el Tesauro Brasileño de Ciencias de la Información y el Diccionario de organización del conocimiento: Clasificación, Indización, Terminología. Los resultados revelan que los temas son predominantemente de base conceptual, seguidos de diálogos interdisciplinarios; los trabajos están a cargo de 26 (veintiséis) instituciones con mayor incidencia de la Universidade Estadual Paulista “Júlio de Mesquita Filho” – Campus Marília; y en cuanto a los estudios terminológicos, con base en la categorización, los términos que prevalecen en los títulos provienen de las áreas de Tratamiento Temático de la Información y Sistemas de Organización del Conocimiento, con un nivel medio de compatibilidad en los instrumentos terminológicos.
Human Resource Aspect in Digital Library Era
Authors: Solanki Mrugesh R.
Published: October 2021

Abstract: Information Communication Technology abbreviated as ICT, is undergoing latest advancement. Library and information professionals need to adopt these changes by enhancing their skills and knowledge to meet the user’s needs. This can be possible by learning and implementing new ICT skills and knowledge through training & development, participating in conferences, seminar, workshop, self learning or any other medical of learning. Now the librarian in this digital era has to be proactive in implementing new tools and technological advancement in the library. This present article focuses the roles and functions of a librarian in this digital era, including information retrieval, navigation and browsing. This paper also summaries the skills, proficiencies, ability and competencies about professional and technological aspects that library professional staff should possess in order to meet the current and future needs of users. It will also help them to not only to survive in a rapidly changing technological environment but also enhance their professional and personal development. Keywords: Human Resource Development, Digital Library, Training and Development, Digital Competencies, Agencies of HRD, Information and Communication Technology (ICT)
Design, Analysis and Development of Digging and Roller Chain Conveying System for Self-Propelled Onion Harvester
Authors: Chhadi Jay
Published: October 2021

Abstract: The history of Agriculture in India dates back to Indus Valley Civilisation. India ranks second worldwide in farm outputs. As of 2018, agriculture employed more than 50% of the Indian workforce and contributed 17–18% to the country's GDP. India has the largest net cropped area, followed by the US and China, yet mechanization in farming is comparatively low compared to developed countries. The lack of technological development and unaffordability of new and competent machines for the average farmer are the few of the reasons for this encumbrance. The development of the onion harvester intends that it will provide a reliable and affordable alternative to traditional farming practices. The digging and conveying systems are the integrated part of the onion harvester. The design of the blade and conveyor is made by using CATIA V5 and analysis of the parts are done using ANSYS Workbench. During design and analysis, severe factors are considered such as preventing the damage to onion bulbs, size of bulbs, soil condition, onion leaves at a predetermined height and roots of the crops to penetrate. This paper is intended to discuss the results of the design and analysis of the digging and conveying systems under the guidelines of the SAE TIFAN rulebook [1]. Keywords: Onion Harvester, Blade Design, Conveyor Design, FEA Analysis.
Seismic Analysis of Lightweight and Conventional Buildings: A Comparative Study
Authors: Yadav Mr. Rajesh Kumar
Published: October 2021

Abstract: In recent decades, the use of light-weight materials over heavy-weight materials has increased at a faster rate. When it comes to cost and resource savings, lightweight construction is considered to be more essential. AAC block is a lightweight construction material that provides good acoustic and thermal insulation. In seismic zones, the use of lightweight materials in building reduces the percentage of damages. The goal of this research is to conduct a project comparison study of seismic analysis of buildings composed of lightweight and conventional materials. RSM creates a structural model of a multi-story structure (G+3) and analyses it in Etabs (Response Spectrum Method). Buildings constructed using infill AAC (Autoclaved aerated concrete) blocks and traditional clay brick masonry are designed for the same seismic hazard in conformity with Indian norms. The buildings' analytical results will be compared. The project also aims to familiarise students with Etabs2016. Keywords: Autoclaved Aerated Concrete, Conventional Brick Replacement, Lightweight Construction, Lightweight Material.
Thesis on Machine Learning Methods and Its Applications
Authors: M S Dharmapriya
Published: October 2021

Abstract: In the 1950s, the concept of machine learning was discovered and developed as a subfield of artificial intelligence. However, there were no significant developments or research on it until this decade. Typically, this field of study has developed and expanded since the 1990s. It is a field that will continue to develop in the future due to the difficulty of analysing and processing data as the number of records and documents increases. Due to the increasing data, machine learning focuses on finding the best model for the new data that takes into account all the previous data. Therefore, machine learning research will continue in correlation with this increasing data. This research focuses on the history of machine learning, the methods of machine learning, its applications, and the research that has been conducted on this topic. Our study aims to give researchers a deeper understanding of machine learning, an area of research that is becoming much more popular today, and its applications. Keywords: Machine Learning, Machine Learning Algorithms, Artificial Intelligence, Big Data.
An Experimental Study on Copper Plates Using Friction Drilling.
Authors: Mule Samadhan Suresh
Published: October 2021

Abstract: Friction drilling is a novel hole-making method that can be performed on thin-walled sheets. In recent years of study, the thrust force and torque under numerous process conditions were performed to demonstrate the benefits. In recent years of study, the thrust force and torque under various process conditions were performed to demonstrate the benefits. Our objective is to review the behavior of the material with the use of friction drilling by variation of thickness, Spindle speed, and feed rate. Our objective is to study the behavior of the material with the use of friction drilling by variation of thickness, Spindle speed, and feed rate. The friction between a rapid rotating conical tool and a sheet metal workpiece generates heat to soften and displace the metal to form a whole. Friction drilling is a non-traditional hole-making process in which a conical rotating tool is applied to penetrate the workpiece and make the outlet in a single step, without generating chips. the process relies on the heat generated thanks to the resistance force between tool and workpiece, to soften, penetrate and deform the work material into a bushing shape. Generally, friction drilling is applied to thin-walled materials owing to increasing connection length and clamping strength. The generated resistance heat cause softening piece of work material, increase its ductility, and providing it to flow, that extruded onto both the front and back sides of the holes. Keywords: Friction Drilling, Conical Tool, Material Displace, Temperature, Hardness & Thickness.
Different Agricultural Wastes as Substrates for Growth and Production of Pleurotus florida
Authors: Hiwale Vishal
Published: October 2021

Abstract: The present study was done impact of agricultural wastes on growth and production by oyster mushrooms i.e., Pleurotus florida which have a rich source of protein and also has important medicinal properties. The yield and Biological efficiency of different lignocellulosic agricultural wastes viz. Wheat straw, Maize leaves, Cob leaves, Jawar residue, Bajra residue, Bamboo leaves, Paddy straw, Sugarcane, Cotton, Soyabean, Safflower (Pods residue), Pigeon pea (Pods residue), Mung bean (Pods residue), Cowpea (Pods residue). the paddy straw showed the highest yield 892.25 gm with the highest biological efficiency 89.09 % followed by Cowpea pods residue gives 879.65 gm yield of Pleurotus florida and shows biological efficiency of 87.72%, followed by Wheat straw substrate showed 871.18 gm yields with 87.27 % biological efficiency. The Pigeon pea pod residue showed 865.85 gm yield during three harvestings having 86.36% biological efficiency. Similar result was seen Bajra residue and soybean pod residue in bajra residue showed 792.45gm yield during three harvestings having 79.245% biological efficiency, in soybean pod residue showed 791.63 gm yield during three harvestings having 79.163 % biological efficiency. The lowest yield was seen in Bamboo leaves and cotton residues. In cotton residue substrate 433.22 gm total yield along with 43.32% biological efficiency, Bamboo leaves substrate total yield were seen 438.12gm with 43.81 % biological efficacy. Keywords: Pleurotus florida, Agricultural waste, Substrates, Biological efficiency
Fusing the Mythological with the Contemporary: A Study of the Revisionist Version of Sita in Amish Tripathis Sita: Warrior of Mithila
Authors: Ramola Tanya
Published: October 2021

Abstract: Sita: Warrior of Mithila (2017), the second book in the Ramachandra series by Amish Tripathi, is a true representative of the genre of revisionist writings. Using the technique of hyperlink, the author portrays Valmiki’s leading lady as a fierce woman unlike other versions of the classical text wherein the character of Sita is docile and much more suppressed without a voice of her own. She is practical and intelligent and has the habit of taking decisions on her own during her adolescence. She is completely opposed to the caste system practised in India that acts as a hindrance in the progress of the country where people blindly follow the rigid caste system, giving utmost importance to their caste and not to their skills or karmas. Tripathi projects the carefree and adventurous character of Sita skilled in various arts. Relationship between nature and Sita is depicted in most of the chapters wherein nature is shown as the protector as well as the destroyer. This paper is an attempt to study the revisionist portrayal of Sita as projected by Amish Tripathi and the various ways this portrayal is different from the various other portrayals of Sita in other contemporary revisionist texts. Keywords:  Dharma  Nation  Complexion  Nature  Caste system  Patriarchy