bluuebunny/crossref_metadata_2025 huggingface dataset:
Phycocyanin from Spirulina platensis Induces Cytotoxicity and Apoptosis in T47D Cells
Authors: Dimarti Safira Chairani , Susilaningsih Neni , Yuniati Renni
Published: May 2020

Breast cancer cases in Indonesia have risen in alarming rate. Herbal medicines have been developed to complement conventional cancer therapy and to lessen the negative effects of the therapies. Phycocyanin, blue-green photosynthetic pigment from Spirulina platensis, becomes a potential candidate of herbal medicine for cancer therapy due to its capability to eliminate various cancer cell line on in vitro level. This research aimed to analyse the effectivity of phycocyanin to induce cytotoxic and apoptotic activity of T47D cells (breast cancer cell line). MTT assay was perform to measure IC50 value. Double-staining assay and flow cytometry were applied to visualize the appearance of apoptotic cells and to measure the percentage of apoptotic and necrotic cells. Result showed that the IC50 value of phycocyanin towards T47D cells is 1650 μg/mL. Phycocyanin was also proven to induce apoptosis at IC50 with the apoptosis percentage of 45.93%. This research presented different results from previous researches that used phycocyanin from saltwater Spirulina platensis. Based on the results of this study, phycocyanin has the potential to be developed as anticancer agent by inducing apoptosis.
Microbiological Quality and Proximate Composition of Bakasang Laor, a Traditional Fermented Fishery Product in Maluku
Authors: Mahulette Ferymon , Kurnia Tri Santi
Published: May 2020

Bakasang laor is one of the traditional fermented fishery products in Maluku, Indonesia. There are two types of  bakasang laor, i.e. with and without vinegar. The microbiological research of bakasang processed use laor as raw material  has never been done before. The research aimed to analyze the microbiological quality and proximate composition of two types of bakasang laor.  The proximate composition can determine the nutritional value of  this product for consumption by the community. The sample of bakasang laor was taken from traditional producer in Latuhalat village, Ambon. The total number of halotolerant and coliform bacteria  in bakasang laor without vinegar were 1.7x106 CFU/g and 4.1x106 CFU/g, respectively, while the total of lactic acid bacteria in bakasang laor with vinegar was 6.0x106 CFU/g.  The carbohydrate, protein, fat and ash contents of bakasang laor with vinegar was higher than bakasang laor without vinegar. The carbohydrate, protein and fat contents of bakasang laor with vinegar were 19.64 %, 16.23 %, and 2.42 %, respectively. Generally, microbiological quality and proximate composition  of  bakasang laor with vinegar was better than bakasang laor without  vinegar. The bacteria that play a role in fermentation can be used as a starter in the fermentation of various food products.  The results of this research to improve the quality of this fermentation product in the future.
The Potential of Cnidoscolus chayamansa Alchoholic Leaves Extract as Hypolipidemia Agent
Authors: Iswari Retno Sri , Mubarok Ibnul , Sasi Fitri Arum
Published: May 2020

Cardiovascular disease caused by hyperlipidemia is the highest case in term of fatality of non-infectious disease in Indonesia. Cnidoscolus chayamansa is well known as a herb that has nutraceutical potential for medicine and likely as a hypolipidemia agent. Therefore, this study aimed to identify the optimal dose of C. chayamansa as a candidate to treat cardiovascular diseases. A total of 30 white rats were acclimatized in the laboratory for 14 days. After that, the rats were grouped into six groups, randomly, which including a healthy control group (K0), a negative control group or hyperlipidemic rats (K-), a positive control group or hyperlipidemia-induced rats that was supplemented with atorvastatin (K+), then a hyperlipidemic rats treated with alcoholic extract of C. chayamansa leaves at doses of 100 mg /kgBB /day for K1, 200 mg/ kgBB/ day for K2 and 400 mg/ KgBB/ day for K3. The results showed that K3 treatment is the most effective and optimum dose for lowering total cholesterol level at 76.81±1.10 mg/dl, triglycerides 72.39±1.66 mg/dl and LDL-C at 21.47±0.58 mg/dl. The aortic histology assessment also showed that the K- group had putative thrombus or plaque in intima, and it was not found in other groups. This research focused on the optimum dose and new usage of C. chayamansa, as an anti-inflammatory in atherosclerosis. By understanding the optimum dose of C. chayamansa, the community can apply and control the herb consumption for their own therapeutic properties. For future application, the herb is potentially developed as anti-atherogenic medicine.
Growth Performance, Yield Component and Genotypic Response of Mungbean (Vignaradiata l.) Against Soil Borne Diseases
Authors: Uge Emerensiana , Iswanto Rudi , Hapsari Ratri Tri , Trustinah Trustinah
Published: May 2020

Soil-borne disease caused by fungus infection is one of the disease that causes the death and crop failure of mungbean. The aim of this study was to identify the performance, yield component and respons of plant to the disease. Performance of 25 genotypes were observed in installations research and assessment of agriculture technology (IPPTP), Jambegede of Indonesian Legumes and Tuber Crops Research Institute (ILETRI)at dry season 2018 using RCBD with three replications. The result showed that each variety has different characteristic. The plant with the highest number of plant height was genotype 15 and 18, while the total branches of 25 genotypes were generally similar (4).The highest number of grown and harvested plant was genotype 15. The genotypes with shorter flowering, maturity and harvesting age were 23, 20, 18, 15 and 10. The highest average number of filled pods was genotype 11 and empty pods was genotype 13. There were 8,10 and 2 genotypes with seeds weight of >7, >6 and <6 respectively. The highest yields were obtained from genotype 19 and 3 by total of yield of 2.0 t/ha and 1,9 ton/ha respectively. Resistance test against soil-borne diseases resulted 5 genotypes that were moderate resistant observed at 2 DAP. This research contributed to gave information about new genotypes of mungbean that potentially produce new superior varieties.
Traditional Knowledge of Banyumas Community about Mesua ferrea as the Identity Plant
Authors: Rahayu Enni Suwarsi , Suharini Erni , Fathonah Siti , Maisah Aisirotul
Published: May 2020

The population of Mesua ferrea L. in Banyumas Regency, Central of Java Province is very low. There are some factors affecting the quantity of plant population, particularly traditional knowledge of local community about the plant. The aim of this study was to describe the knowledge of Banyumas community about the existence, economic value, usefulness, and propagation technique of M. ferrea. The study was done by field survey on a total of 146 residents from 10 districts which were determined by proportionally stratified random sampling. Data obtained from questionnaires and interviews were analyzed by percentage descriptive. The results revealed that only 9% of respondents were familiar with the M. ferrea and knew its status as plant identity of Banyumas Regency. Most of the respondents did not understand the economic value, only 8% of respondents understood the usefulness, 2% of respondents had utilized the timber as craft material, and 3% understood the propagation technique. The utilization was very low, equal to 14.45% compared to the potential usefulness. Most of the respondents (98%) thought that conservation efforts should be undertaken. This study found that the traditional knowledge of M. ferrea in Banyumas was low. This result should be used as a basic information for developing conservation program of M. ferrea.
Lesiones toracolumbares en la práctica de acrobacia en tela. Reporte de casos
Authors: Bazán Pedro Luis , Marín Elio , Betemps Alejandro , Borri Álvaro Enrique , Medina Martín , Ciccioli Nicolás Maximiliano , Reble Javier
Published: May 2020

Introducción: La acrobacia en tela es una práctica circense con muchos adeptos en la población urbana. Consiste en sostenerse en altura tomado por dos extremos de tela, para realizar posturas fijas y cambiar entre ellas mediante deslizamiento y caídas. La práctica profesional no está libre de lesiones.
Objetivo: Conocer la naturaleza de la lesión, reconocer los factores predisponentes de lesión y las medidas de prevención utilizadas, evaluar la cinemática, clasificar la lesión y analizar el tratamiento.
Materiales y Métodos: Se incluyeron seis pacientes. Se evaluaron la estructura física personal, la cinemática de la caída, los sistemas de protección, la clasificación de las fracturas según la nueva clasificación AO, el cuadro neurológico, el tratamiento y las complicaciones.
Resultados: La muestra incluyó a 6 mujeres, con un promedio de edad de 24 años y un índice de masa corporal de 19,29. Caída de 3,08 m de altura, cuatro con colchoneta <5 cm. Las lesiones principales fueron: 6 A1, 4 B2 y 1C. No se observaron déficits neurológicos. Cuatro pacientes fueron sometidas a cirugía.
Conclusiones: La práctica de acrobacia en tela es una actividad circense de reciente aparición global. Las mujeres están más expuestas a las lesiones. El entrenamiento riguroso y el empleo de elementos de seguridad son necesarios para evitar las lesiones. No se observó un patrón único de lesión, la causa fue multifactorial. El tratamiento indicado depende de la lesión vertebral.
Artroplastia total de rodilla en pacientes con secuela de fracturas articulares. Resultados del seguimiento a mediano plazo
Authors: Simesen de Bielke Harold , Pérez Alamino Leonel , Aguer Santiago , Garabano Germán , Del Sel Hernán , Lopreite Fernando
Published: May 2020

Introducción: Las fracturas articulares de rodilla son frecuentes y pueden evolucionar a gonartrosis postraumática. El tratamiento en su estadio final es el reemplazo total de rodilla (RTR). Cuando se indica, el especialista se enfrenta a situaciones que predisponen a resultados menos satisfactorios. El objetivo de este estudio fue evaluar los resultados del RTR en pacientes con secuela de fracturas articulares de rodilla, con un seguimiento mínimo de 4 años.
Materiales y Métodos: Estudio retrospectivo observacional, entre mayo de 1999 y enero de 2013. Se evaluaron 25 RTR en 24 pacientes (edad promedio 67.1 años) con secuela de fractura articular de rodilla y un seguimiento promedio de 6.1 años. Tres (12%) tenían cirugías anteriores al RTR. Ocho se resolvieron en dos tiempos. Se empleó un implante constreñido en 4 pacientes (16%). Se determinaron el KSS, el KSSf y el rango de movilidad preoperatorios y del último control. Se documentó la supervivencia del implante.
Resultados: El KSS se incrementó de 38,5 en el preoperatorio a 82,8 en promedio. El KSSf posoperatorio mejoró de 48 a 85. El rango de movilidad aumentó de un promedio de 7,5-76° a 1-102,4° en el posoperatorio. Cuatro casos fueron reoperados. La supervivencia de la prótesis fue del 92% a los 6.1 años.
Conclusiones: El RTR es adecuado para la gonartrosis postraumática en su estadio final, con buenos resultados a mediano plazo. Si se logran una adecuada alineación posoperatoria y un correcto posicionamiento de los componentes, los resultados son satisfactorios y se asemejan a los del RTR por gonartrosis idiopática.
Instrucción Ortopédica de Posgrado - Imágenes. Resolución del caso.
Authors: Trueba Ricardo
Published: May 2020

Se describe la fisiopatologia de la entidad nosologica y las imagenes diagnosticas
Manejo y tratamiento de pacientes en áreas quirúrgicas durante la pandemia COVID-19. Revisión en el área de Ortopedia y Traumatología
Authors: Cattáneo Andrés , Coppola Esteban F. , Medina A. Federico , Pachón Guzmán Alejandro
Published: May 2020

La pandemia actual ocasionada por el coronavirus (COVID-19) ha promovido el desarrollo de gran cantidad de medidas en el ámbito individual y global, que afectan gravemente a los sistemas de salud. Aunque la epidemia no involucra directamente a los especialistas en Ortopedia y Traumatología, indirectamente, nos vemos compelidos a implementar medidas hospitalarias preventivas tendientes a disminuir las posibilidades de contagio durante nuestros procedimientos específicos. Esta breve revisión bibliográfica pretende aportar información dinámica básica respecto a de qué manera actuar como especialistas en las áreas quirúrgicas ante casos sospechosos/confirmados de COVID-19. Promovemos el diseño de planes de trabajo para la atención de pacientes antes de la cirugía, durante esta y después.
Resultados de la osteotomía y osteosíntesis rígida en la consolidación viciosa de falange
Authors: Rellán Ignacio , Ferreira Luis , De Carli Pablo , Gallucci Gerardo Luis , Donndorff Agustín , Zaidenberg Ezequiel Ernesto , Boretto Jorge Guillermo
Published: May 2020

Objetivo: Evaluar los resultados y las complicaciones de una serie de pacientes con consolidación viciosa de falange. Materiales y Métodos: Se realizó un estudio retrospectivo que incluyó a pacientes con consolidación viciosa de falange tratados mediante osteotomía en el sitio de la deformidad, estabilizados con osteosíntesis rígida. Se registró la movilidad de los dedos. La valoración subjetiva consistió en el puntaje DASH y una escala analógica visual para el dolor en reposo, en actividad y la función. Resultados: Doce pacientes (13 falanges) cumplieron los criterios de inclusión. El tiempo promedio entre la lesión inicial y la osteotomía fue 14 meses y el seguimiento promedio, 34 meses. La movilidad final promedio en flexo-extensión fue 89° metacarpofalángica, 74° interfalángica proximal, 54° interfalángica distal y la distancia pulpejo-palma, 3 mm. El puntaje promedio de la escala analógica visual en reposo fue 0; en actividad, 1 y la función promedio fue de 7 puntos; el puntaje DASH promedio fue 6. No hubo casos de seudoartrosis. Cinco pacientes requirieron el retiro de la placa. Los pacientes con osteotomía articular no presentaron signos de artrosis. Conclusiones: La osteotomía de falange en el sitio de la deformidad es un procedimiento eficaz con un buen resultado objetivo y subjetivo a corto plazo. La utilización de placas y tornillos conlleva una tasa más alta de complicaciones; por lo tanto, los pacientes deben ser advertidos sobre la posibilidad de una segunda intervención quirúrgica.
Flegmasia cerúlea dolens posquirúrgica inmediata en el tratamiento de una fractura de pelvis. Reporte de Caso
Authors: Vivas Mauro Rafael , Román Ezequiel , Bizzarri Pablo , Lias Ariel , Romano Osvaldo
Published: May 2020

La flegmasia cerúlea dolens es una presentación poco habitual y grave de una trombosis venosa profunda producida por una obstrucción al flujo venoso de salida de la extremidad inferior, que conlleva un alto grado de morbilidad. Este cuadro no ha sido comunicado como complicación del tratamiento definitivo de una fractura de pelvis. Consideramos que una breve descripción del tema y la presentación de un caso pueden ser útiles para el cirujano ortopédico ante una situación similar.
Reemplazo total de cadera en un paciente con amputación supracondílea homolateral
Authors: Wagner Edgar Gustavo , Quiroga Reynaldo
Published: May 2020

Las fracturas de cadera en pacientes con amputación del miembro homolateral son lesiones infrecuentes que representan un reto para el cirujano ortopédico. Presentamos el caso de un hombre de 63 años con amputación supracondílea izquierda, que sufre una fractura de cuello femoral izquierdo por caída de su propia altura. La colocación apropiada del implante es esencial para obtener buenos resultados clínicos posoperatorios. Para la exposición y la colocación del implante se utilizó un clavo de Steinmann en el trocánter mayor. No se observaron complicaciones clínicas ni radiográficas en un seguimiento de 15 meses. Creemos que el empleo del clavo de Steinmann colocado en una correcta posición es una buena alternativa por considerar para poder controlar el miembro al realizar una artroplastia y así disminuir los riesgos de colocar la prótesis en mala posición y el tiempo quirúrgico.
Osteomielitis de tibia secundaria a la vacuna BCG en un paciente pediátrico inmunocompetente. Reporte de un caso
Authors: Dal Lago Javier Eugenio , Levy Eduardo Jacobo
Published: May 2020

Introducción: La vacuna BCG (bacilo de Calmette-Guérin) para prevenir las formas graves de tuberculosis, es la vacuna más difundida en el mundo. Los efectos adversos asociados a la vacunación son poco frecuentes, y la mayoría de ellos ocurren en el sitio de inoculación. Presentamos un caso de osteomielitis de tibia secundaria a la vacuna BCG en un paciente pediátrico inmunocompetente.
Conclusiones: El compromiso óseo secundario a la vacuna BCG en pacientes previamente sanos es muy raro. Es importante sospecharlo, para diagnosticarlo y administrar el tratamiento adecuado. Se obtuvieron buenos resultados administrando fármacos antituberculosos, sin necesidad de limpieza quirúrgica.
Tratamiento con clavo endomedular de las fracturas metafisarias proximales y distales de tibia. Abordaje pararrotuliano medial en posición de semiextensión
Authors: Pereira Sebastián , Vindver Gabriel , Bidolegui Fernando
Published: May 2020

El enclavado endomedular de las fracturas metafisarias de tibia se asocia con algunas complicaciones relacionadas con la necesidad de flexionar la rodilla durante la introducción del clavo endomedular con la técnica infrarrotuliana clásica. Es por ello, que se han diseñado diferentes abordajes para la colocación del clavo en una posición de semiextensión de rodilla. El objetivo fue evaluar nuestros resultados, de forma retrospectiva, con el abordaje pararrotuliano medial en semiextensión, para el tratamiento de las fracturas metafisarias proximales y distales de tibia con clavo endomedular.
Materiales y Métodos: Se incluyó a 23 pacientes con un seguimiento posoperatorio mínimo de un año. Doce eran fracturas distales de tibia; 9, proximales y 2, segmentarias. Se evaluaron el rango de movilidad de la rodilla, el dolor posoperatorio con la escala de Lysholm, el eje posoperatorio y la tasa de consolidación.
Resultados: El arco de movilidad de la rodilla fue de 125° (rango 110-140). Al año de la cirugía, 16 de 23 pacientes no tenían dolor, 5 de 23 refirieron un leve dolor durante la actividad física y 2, dolores intensos durante la actividad física. En todos los casos, se consiguió un eje posoperatorio aceptable y la consolidación ósea. Un paciente requirió un aumento con una placa e injerto óseo.
Conclusión: La colocación de un clavo de tibia a través de un abordaje pararrotuliano medial con la rodilla en semiextensión es una técnica segura y simple para el tratamiento de las fracturas metafisarias de tibia.
Resultados funcionales y radiográficos de la prótesis reversa y la reinserción del troquíter en pacientes con fracturas de húmero proximal
Authors: Patiño Juan Martín , Martínez Carlos Eugenio , Andres Bernardo , López Bustos Francisco , Ruiz César , Fiminella Hernán , Ferro Julio , Garay Alberto
Published: May 2020

Objetivo: Comunicar los resultados funcionales y radiográficos de pacientes tratados con prótesis reversa por fracturas complejas. El objetivo secundario fue determinar la relación entre rangos de movilidad y puntaje ASES con la evolución radiográfica del troquíter.
Materiales y Métodos: Se incluyeron 16 pacientes >65 años, tratados con prótesis reversa y reinserción del troquíter, entre 2013 y 2017, operados antes de las 4 semanas del trauma y con un seguimiento mínimo de 2 años. Se consignaron el puntaje ASES y el rango de movilidad activa. En las radiografías, se evaluaron la posición y la consolidación del troquíter, y se registraron las complicaciones y su tratamiento.
Resultados: La media de la edad fue 74.5 años (RIC 66-78.5), 11 (69%) eran mujeres. Once fracturas (69%) eran a 4 fragmentos y 5, luxofracturas a 4 fragmentos. La media entre el trauma y la cirugía fue 9.4 días y el seguimiento, 29.5 meses. En 9 casos (56%), el troquíter presentó consolidación. Rotación interna: 5 pacientes alcanzaron la región glútea con el pulgar; 4, la vértebra T12; 4, la vértebra L3; 3, la T7. Las medianas de rotación externa y flexión anterior fueron 30° (RIC 17,5-40) y 100° (RIC 87,5-160). El puntaje ASES promedio fue 78,3 (RIC 63,3-87,4). No hubo una asociación estadísticamente significativa entre la evolución del troquíter y la flexión anterior y el puntaje (p = 0,24 y 0,52, respectivamente).
Conclusión: La prótesis reversa en fracturas agudas con reinserción de las tuberosidades puede llevar a buenos resultados funcionales. No se encontró relación entre la consolidación del troquíter y el puntaje ASES.
Emancipating lenes
Authors: Szigetvári Péter
Published: May 2020

I argue that English has no voicing assimilation, in fact, it does not have phonologically voiced segments at all. Voicing in English is spontaneous in sonorants, while obstruents may be phonetically voiced only if lenis and surrounded by spontaneously or passively voiced sounds. The paper claims that most obstruent clusters of English are traditionally misanalysed as fortis+fortis clusters. These clusters are all either fortis+lenis or lenis+fortis; in fact, fortis+fortis clusters are completely ruled out in English.
Implementation of Image Enhancement Algorithm for Image Forensics using Mathlab
Authors: Suteja Fauzan Novaldi , Hidayat Eka Wahyu , Widiyasono Nur
Published: May 2020

The purpose of this journal is to explain the implementation of the image enhancement algorithm for image forensics. Image Forensic deals with the types of digital evidence in the form of digital image files. One of the most commonly used digital devices in providing digital evidence for forensic analysis is CCTV (Closed-Circuit Television). CCTV images have a low quality such as noise, blur, lack of light intensity, etc., so that the image must be enhanced so that forensic analysis can be done. To enhance image quality, an application is needed by applying the image enhancement algorithm. The algorithm applied to the application is a Low Pass Filter to increase low pixel intensity, High Pass Filter to increase high pixel intensity, Median Filter to replaces the original pixel value with the pixel center value of the image, Mean Filter to replaces the original pixel value with a value the average pixel of the image, the Gaussian Filter for reducing noise in the image, the Wiener Filter to reduce blur in the image, the Histogram Equalization spreads the image histogram value, Contrast Stretching to stretch the contrast intensity in the image and Bicubic Interpolation to increase the image size and resize the image. In this study, the application was built using MATLAB and the testing process for each algorithm was based on Timing-Run, MSE and PSNR parameters. From the test, the average MSE value is 1058.512083 and the PSNR value is 541.61875 dB, which means that the resulting image has a fairly high level of similarity and the average time needed to process the algorithm for the image is 0.114627915 seconds.
Lossless Text Image Compression using Two Dimensional Run Length Encoding
Authors: Nuha Hilal H
Published: May 2020

Text images are used in many types of conventional data communication where texts are not directly represented by digital character such as ASCII but represented by an image, for instance facsimile file or scanned documents. We propose a combination of Run Length Encoding (RLE) and Huffman coding for two dimensional binary image compression namely 2DRLE. Firstly, each row in an image is read sequentially. Each consecutive recurring row is kept once and the number of occurrences is stored. Secondly, the same procedure is performed column-wise to the image produced by the first stage to obtain an image without consecutive recurring row and column. The image from the last stage is then compressed using Huffman coding. The experiment shows that the 2DRLE achieves a higher compression ratio than conventional Huffman coding for image by achieving more than 8:1 of compression ratio without any distortion.
Diagnosis of Types of Diseases in Cassava Plant by Bayes Method
Authors: Sidik Agung Purnomo
Published: May 2020

This research was conducted to implement the Bayes algorithm in an expert system to diagnose types of diseases in cassava plants. The research data was taken from the Binjai City Agriculture and Fisheries Office in 2018. The expert system was built based on the web, where the application was built using the PHP programming language and MySQL DBMS. The results showed that the Bayes algorithm can be used in expert system applications to diagnose types of cassava plant diseases. In the Bayes algorithm, the knowledge base is taken from the data of the amount of data from cassava plants that suffer from disease, so the results of diagnosing cassava plants are based on existing data. Therefore, the more patient data that is used as a knowledge base, the better the diagnosis results are given.
Security Scanner For Web Applications Case Study: Learning Management System
Authors: Andrian Rian , Fauzi Ahmad
Published: May 2020

In software engineering, web applications are software that are accessed using a web browser through a network such as the Internet or intranet. Web applications are applications that can be relied on by users to do many useful activities. Despite the awareness of web application developers about safe programming practices, there are still many aspect in web applications that can be exploited by attacker. The development of web applications and the Internet causes the movement of information systems to use them as a basis. Security is needed to protect the contents of web applications that are sensitive and provide a safe process of sending data, therefore application security must be applied to all infrastructure that supports web applications, including the web application itself. Most organizations today have some kind of web application security program or try to build/ improve. But most of these programs do not get the results expected for the organization, are not durable or are not able to provide value continuously and efficiently and also cannot improve the mindset of developers to build/ design secure web applications. This research aims to develop a web application security scanner that can help overcome security problems in web applications.
Load Balancing Network by using Round Robin Algorithm: A Systematic Literature Review
Authors: Hidayat Taufik , Azzery Yasep , Mahardiko Rahutomo
Published: May 2020

The use of load balance on a network will be very much needed if the network is an active network and is widely accessed by users. A reason is that it allows network imbalances to occur. Round Robin (RR) algorithm can be applied for network load balancing because it is a simple algorithm to schedule processes so that it can provide work process efficiency. Authors use the Systematic Literature Review (SLR) method in which it can be applied for criteria selection during papers search to match the title being raised. SLR is divided into five stages, namely formalization of questions, criteria selection, selection of sources, selection of search results, and quality assessment. By using SLR, it is expected that papers according to criteria and quality can be found.
The generalized Drazin inverse of operator matrices
Authors: GUO Li , ZOU Honglin , CHEN Jianlong
Published: May 2020

Representations for the generalized Drazin inverse of an operator matrix $\begin{pmatrix}A & B \\ C & D \end{pmatrix}$ are presented in terms of $A,B,C,D$ and the generalized Drazin inverses of $A,D$, under the condition that $BD^d=0,~\text{and}~BD^iC=0,~\text{for any nonnegative integer}~ i.$ Using the representation, we give a new additive result of the generalized Drazin inverse for two bounded linear operators $P,Q \in \mathbf{B}(X)$ with $PQ^{d}=0$ and $PQ^{i}P=0$, for any integer $i\geq 1$. As corollaries, several well-known results are generalized.
Neumonía por COVID-19 y uso de Tocilizumab: Reporte de Caso
Authors: Bernaola Ursula Cáceres , Núñez Claudia Becerra , Tai Sabina Mendívil-Tuchía de , Ravelo-Hernández Jorge
Published: May 2020

Se presenta el caso de un paciente adulto con neumonía por COVID-19 de rápida progresión clínico-radiológica, en quien se planteó el uso compasivo de bloqueador de receptor de interleucina 6 (Tocilizumab) para el manejo de su patología.
FAMILY SUPPORT AGAINST COVID-19
Authors: Socías Carmen Orte , Brage Lluís Ballester , Nevot-caldentey Lluc
Published: May 2020

On March 14, 2020, the Spanish Government declared a state of alarm to face the health emergency situation caused by the rapid evolution of the COVID-19 pandemic. The greatest impact of the restrictions, due to the lack of contact with the main areas of socialization, has been on childhood and adolescence. The increase in the rates of family violence and the abusive consumption of gambling and / or pornography show the need to reinforce family prevention measures1,2. A review of the main family prevention measures applied in Spain was carried out and complementary measures identified at the international level are proposed. Much of the Spanish prevention measures are tertiary in nature. Telephone psychological support was the most widely applied measure. The need to prevent infant-juvenile risks in confinement, aimed at enhancing family skills, is concluded.
CONSECUENCIAS DE LA PANDEMIA COVID 19 EN LA SALUD MENTAL ASOCIADAS AL AISLAMIENTO SOCIAL
Authors: Ramírez-Ortiz Jairo , Castro-Quintero Diego , Lerma-Córdoba Carmen , Yela-Ceballos Francisco , Escobar-Córdoba Franklin
Published: May 2020

La pandemia por coronavirus 2019 (COVID-19) es una emergencia de salud pública de preocupación internacional, con impactos sin precedentes en el siglo XXI y hoy representa un gran desafío a la salud mental. Estudios en epidemias anteriores han revelado una profunda y amplia gama de consecuencias psicosociales a nivel individual y comunitario durante los brotes. Son múltiples las alteraciones psicológicas asociadas que van desde síntomas aislados hasta trastornos complejos con un deterioro marcado de la funcionalidad, tales como insomnio, ansiedad, depresión y trastorno por estrés postraumático. En este contexto es necesario que las entidades de salud mental desarrollen estrategias que permitan reaccionar con destreza y que logren un soporte al personal de salud y a la población afectada, en aras de reducir el desarrollo del impacto psicológico y de los síntomas psiquiátricos. Este artículo de reflexión tiene por objetivo, mostrar las posibles consecuencias en la salud mental de la población que pueden llegar a suceder como resultado del aislamiento social debido a la pandemia del COVID-19.
PROGNOSTIC FACTORS FOR CLINICAL COURSE OF PATIENTS WITH COVID-19: PROTOCOL FOR A RAPID LIVING SYSTEMATIC REVIEW
Authors: Puga Maria Eduarda dos Santos , Rocha-Filho César Ramos , Pinto Ana Carolina Pereira Nunes , Rocha Aline Pereira da , Milby Keilla Martins , Reis Felipe Sebastião de Assis , Civile Vinicius Tassoni , Carvas Junior Nelson , Santos Rodolfo Rodrigo Pereira , Ramalho Gabriel Sodré , Trevisani Giulia Fernandes Moça , Ferla Laura Jantsch , Puga Maria Eduarda dos Santos , Trevisani Virgínia Fernandes Moça , Atallah Alvaro Nagib
Published: May 2020

CONTEXT AND OBJECTIVE: Determining prognostic factors in a context of health crises such as the COVID-19 scenario may provide the best possible care for patients and optimize the management and the resource utilization of the health system. Thus, we aim to systematically review the prognostic factors for different outcomes of patients with COVID-19. DESIGN AND SETTING: Protocol for a rapid living systematic review methodology following the recommendations proposed by the Cochrane Handbook. METHODS: We will include cohorts and case‐control studies. We will search Medline via PubMed, Embase via Elsevier, Cochrane Library - Cochrane Central Register of Controlled Trials (CENTRAL), Portal Regional BVS- LILACS, Scopus and WebofScience to identify studies. No language restrictions will be applied. We will perform the critical appraisal of included studies with the Quality in Prognosis Studies (QUIPS) tool and the certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE).
Telehealth interventions in the context of the COVID-19 pandemic: Protocol for a scoping review
Authors: Puga Maria Eduarda dos Santos , Reis Felipe Sebastião de Assis , Milby Keilla Martins , Pinto Ana Carolina Pereira Nunes , Rocha-Filho César Ramos , Rocha Aline Pereira da , Carvas Junior Nelson , Civile Vinicius Tassoni , Santos Rodolfo Rodrigo Pereira , Ramalho Gabriel Sodré , Trevisani Giulia Fernandes Moça , Ferla Laura Jantsch , Puga Maria Eduarda dos Santos , Atallah Alvaro Nagib , Trevisani Virgínia Fernandes Moça
Published: May 2020

CONTEXT AND OBJECTIVE: The current health crisis due to COVID-19 is forcing us to profoundly rethink our social organizations and practices in health. While there is no effective treatment for the virus, staying home and social isolation are the control measures recommended by health authorities. The aim of this study is to perform a scoping review in order to summarize the current evidence in telehealth for COVID-19. METHODS: This study is a protocol to describe the rationale, hypothesis and planned methods of our scoping review. We will include randomized controlled trials (RCTs), observational cohort studies, case-control studies, cross-sectional studies, qualitative studies, and/or case series that describe telehealth interventions applied or developed to respond to COVID-19. We will search Medline via PubMed, Embase via Elsevier, Cochrane Library - Cochrane Central Register of Controlled Trials (CENTRAL), Portal Regional BVS - LILACS, and Scopus. We will include studies performed since December 2019 with no language restrictions. We will use the Risk of Bias tool and the Newcastle-Ottawa Scale to perform the critical appraisal of included studies. We will assess the certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE).
Limitar la exposición de las personas más vulnerables como estrategia para minimizar los fallecimientos por COVID-19
Authors: Buján Pérez Alejandro , Domínguez Ignacio López , Garcia Pablo Mallaina , Fresneda Ramiro Romero
Published: May 2020

Cercanos al levantamiento de las medidas de confinamiento que se tomaron para reducir la velocidad de contagio y evitar la saturación del sistema sanitario provocado por la pandemia de COVID-19, sugiere hacer planteamientos de cómo afrontarlo, aplicado en este caso concreto a España.
Se plantean estrategias hasta que la población contagiada supere el umbral de la inmunidad de grupo: una salida proporcional sin filtrar, una reapertura limitando por edad (primera estrategia) y un desconfinamiento más selectivo restringiendo salidas por edad a personas sin enfermedades crónicas (segunda estrategia).
Los resultados obtenidos muestran reducciones en el número potencial de fallecidos del 82.56 % si se limitase la reapertura por edad y del 95.34 % si se restringiese por edad y sin enfermedades crónicas. Así, se reduciría la letalidad del 1.04 %, al 0.18 % y 0.05 % respectivamente.
Pre-deflecting a steel platform to support a new organ at Manchester Cathedral, UK
Authors: Cochrane Emma , Blackett-Ord Charles
Published: May 2020

The cathedral in Manchester, UK, is one of the most impressive examples of a late mediaeval collegiate church in England. The cathedral has been without a permanent organ since the 1940s, and since then, there has been an aspiration to reinstate one. In 2010, the cathedral commissioned a new grander organ, almost twice the size of its predecessor and weighing approximately 15 t. It was to be positioned beneath the chancel arch, in a prominent central setting between the nave and the choir. The organ would be supported 3.5 m above ground level on a suspended steel platform concealed within the pulpitum. The challenge was to provide a platform within the constraints of not loading the mediaeval rood screen, no visible structure, no discernible deflection during the construction of the organ and with full reversibility. The steel platform was preloaded with a series of lead weights to induce the permanent deflections before the building of the organ itself was started. The lead weights were sequentially removed during the organ building to control the deflection and the load transfer to the existing Victorian cast-iron structure.
Boyun, Bel ve Diz Ağrısı Olan Yaşlılarda Fizik Tedavi ve Balneoterapi, Retrospektif Çalışma
Authors: DİLEKÇİ Erdal , ÖZKUK Kağan
Published: May 2020

Amaç:Çalışmanın amacı,
boyun bel ve diz ağrısı olan yaşlı bireylerde balneoterapinin fizik tedaviye
olan katkısını incelemektir.Gereç
ve yöntem: Bu retrospektif çalışmada, 2013 ve 2018 yılları arasında
fizik tedavi veya fizik tedavi+balneoterapi alan hastaların kayıtları
incelendi. Tespit edilen 704 yaşlı hasta arasından değerlendirme parametreleri
tam olan 482 hastanın verileri analiz edildi. Bulgular: Hastaların
196sına sadece fizik tedavi uygulanmıştı (grup 1). 286 hasta hem fizik hemde
balneoterapi uygulanmıştı(grup2). 173 hasta boyundan, 338 hasta belden, 287
hasta belden tedavi almıştı. Genel değerlendirmede 482 hastada Ağrı Görsel
Analog Ölçeği (VAS) ve 276 hastada Sağlık Değerlendirme Anketi (HAQ), boyundan
tedavi alan 173 hastada VAS, 120 hastada HAQ, 
belden tedavi alan 338 hastada VAS, 238 hastada HAQ ve dizden tedavi
alan 287 hastada VAS, 177 hastada HAQ, sonuçları incelendiğinde tedaviden sonra
değerlendirilen tüm sonuç ölçütlerinde istatistiksel olarak anlamlı bir
iyileşme bulundu. Grup 2 de iyileşme oranları istatistiksel olarak grup 1’den
daha yüksekti.Sonuç: Bu çalışmanın
sonunda boyun, bel ve diz ağrısı olan yaşlılarda fizik tedavi uygulamaları ağrı
ve yaşam kalitesi üzerine etkili olduğu saptanmıştır. Tüm vücut uygulanan
balneoterapi fizik tedavinin etkinliğini arttırabilir.
HİPERTANSİYON KONTROLÜNDE TAMAMLAYICI VE BÜTÜNLEŞİK (İNTEGRATİF) TEDAVİ ÖRNEĞİ: MASAJ
Authors: CEYHAN Özlem , ARSLAN Gürcan
Published: May 2020

Hipertansiyon, dünya genelinde hem
gelişmiş hem de gelişmekte olan ülkelerde yaklaşık bir milyar insanı
etkilemekte olup kardiyovaküler hastalıklardan kaynaklanan ölümlerin en önemli
nedenlerinden biridir. Kan basıncı yüksekliği ile vasküler hastalıklar arasında
yüksek oranda ilişki olduğuna dikkat çeken çalışmalar gösteriyor ki, kan basıncında
meydana gelen küçük bir düşüş bile kardiyovasküler komplikasyonların  (özellikle inme) önlenmesine katkıda bulunabilir.
Bu nedenle esansiyel hipertansiyonun önlenmesi ve etkin tedavisi büyük önem
taşımaktadır. Farmakolojik tedavinin kan basıncını kontrol altına almada ve
hipertansiyonu olan bireylerin yaşam kalitesini yükseltmede yeterli etkiyi
oluşturamadığı düşünülmekte, günden güne hasta sayısının artması ve kullanılan
antihipertansif ilaçların olumsuz etkileri nedeniyle bireyler farklı tedavi
yöntemleri arayışına girmektedir.  Günümüzde
sıklıkla medikal tedaviyle birlikte tercih edilen tamamlayıcı ve bütünleşik
(integratif) tedaviler arasında olan yoga, akupunktur ve masaj gibi
iyileştirici ve yan etki düzeyi az olan yöntemler kronik hastalığı olan
bireyler tarafından kullanılmaktadır.

Tamamlayıcı ve bütünleşik (integratif) tedaviler
arasında yaygın olan yöntemlerden biri ise masajdır. Eisenberg et al.
tarafından yapılan çalışmada, tamamlayıcı ve bütünleşik (integratif) tedavi
yöntemlerine başvuran hastaların yaklaşık yarısı masaj uygulamasını tercih etmektedir.
Hipertansiyon, kardiyak cerrahi sonrası rehabilitasyon, baş ağrısı, demans, stres,  fibromiyalji, osteoartrit, yorgunluk ve meme
kanseri gibi birçok kanser türünün semptomlarını hafifletmek ve yaşam
kalitesini artırmak için kullanılmaktadır.

Masajın, kan basıncı üzerine vücuttaki kan
akışını dengelemesi ve gevşeme cevabının bir sonucu olduğu yapılan meta-analiz
çalışmaları ile desteklenmektedir. Son yıllarda çok sayıda yapılan randomize
kontrollü çalışma kan basıncını kontrol altına almada destekleyici yöntem
olarak masajın kullanılmasının etkili olduğunu bildirilmiştir.

Bu makalede, masajın olumlu etkileri göz önüne
alındığında hipertansiyon yönetiminde nonfarmakolojik bir yöntem olarak
uygulanabileceği önerilmektedir.
Propolis- Literatür Ne Diyor?
Authors: ÜNAL Mustafa , ÖZTÜRK Onur , SELÇUK Mustafa Yasin , ORUÇ Muhammet Ali
Published: May 2020

Propolis, baldan sonra insanlar
tarafından bilinirliği en yüksek arı ürünüdür. Propolisin anti mikrobiyal, anti
inflamatuar, rejeneratif, immun modulatör, anti kanser, anti oksidan vs birçok
etki gösterdiği bilinmektedir. Propolis hakkında çok sayıda preklinik çalışma
olmasına rağmen bunları kliniğe uyarlamak zordur. Propolisin organizma üzerine
sağlığı koruyucu ve iyileştiri etkileri göz önüne alındığında daha fazla ilgiyi
hak ettiği yadsınamaz bir gerçektir, bu yüzden klinik çalışmalar üretilmeli ve
desteklenmelidir.
Etilen Glikolün Mide Üzerine Etkisi: Histolojik Çalışma
Authors: KARABULUT Derya , KAYMAK Emin , YALÇIN Betül , ÜLGER Harun , AKİN Ali Tuğrul , ÖZTÜRK Emel , YAKAN Birkan
Published: May 2020

Özet

Etilen glikol (antifriz) yanlışlıkla
ya da intihar amaçlı sindirim yoluyla alınması sonucu kısa sürede şiddetli
belirtiler göstermekte, yaşam kalitesini etkilemekte uygun tedavi edilmediği
takdirde ölüme neden olabilmektedir. Bu çalışmada etilen glikolün sıçan midesi
üzerinde etkilerinin histolojik ve immunohistokimyasal yöntemlerle
araştırılması amaçlanmıştır. Projede sıçanlar rastgele 2 gruba ayrılarak
metabolik kafeslere yerleştirildi. Kontrol grubu (6 adet) ve Etilen
glikol grubu (grup EG) (6 adet). Grup EG sıçanlarının içme sularına 21 gün
boyunca %1 etilen glikol eklendi. 21 günün sonunda sıçanlar ketamin + xylazin anestezisi altında uyutularak mideleri
alındı. Mide doku kesitlerine hematoksilen-eozin boyaması ve ghrelin-pozitif
hücreleri belirlemek amacıyla immünohistokimya uygulandı. Kontrol grubuyla
kıyaslandığında EG grubuna ait mide doku epitelizasyonunda bozulmalar gözlendi.
Ghrelin-immunopozitif hücre sayısında ise kontrol grubuna kıyasla EG grubunda
artış olduğu belirlendi. Sonuç olarak, ghrelin-immunopozitif hücre sayısındaki artış,
EG alımı sonrasında bozulmuş fizyolojinin düzeltilmesine katkı sağlayabilir.
Çocuklarda Akut,Komplike Apandisit ve Karın Ağrısı Gözlem Hastalarında Hemogram Parametreleri ve C-reaktif protein Değerlerinin Karşılaştırılması
Authors: DOĞAN Gül , İPEK Hülya , DEMİR Emre , AFŞARLAR Çağatay Evrim
Published: May 2020

Amaç:Dünyada
akut karının yaygın nedenlerinden biri olarak kabul edilen apandisitin tanısı
özellikle çocukluk çağında zordur ve başka hastalıklarla karışabilmektedir.Çalışmamızdaakut,komplike
apandisit tanısı alan ve karın ağrısı nedeniyle klinik izleme alınan  hastaların ilk yatışlarında alınan c-reaktif
protein (CRP) ve hemogram parametrelerinin analiz edilerek aralarındaki
ilişkinin ortaya konulması amaçlanmıştır.

Gereç
ve Yöntem: Ocak 2016-Mayıs 2017 tarihleri arasında hastanemize
karın ağrısı yakınması ile başvuran 573 çocuk hasta geriye dönük olarak
tarandı. Hastalar karın ağrısı nedeniyle takip edilenler,akut ve
komplikeapandisitolanlarolmak üzere üç gruba ayrıldı. Tüm hastaların demografik
verileri,CRP,hemogram parametreleri ve bundan türetilen oranlar kaydedildi.

Bulgular:
NLO, WBC/MPV, CRP/MPV, PLO ve MPV/L değerleri apendektomi yapılan hastalarda
karın ağrısı gözlem grubundan daha yüksek çıkmıştır (p<0.001).Hb, MCV, MPV,
htc, platelet sayıları gruplara göre istatistiksel olarak anlamlı farklı
değildi (p>0.05)

Sonuç:
NLO, WBC/MPV, CRP/MPV, PLO ve MPV/L değerlerinin apendektomi yapılan hastalarda
daha yüksek çıkması nedeniyle operasyona karar vermede yada karın ağrısı
gözlemleri belirlemede bu parametrelerin tanıyı destekleyeceği kanaatindeyiz.
Concurrent Bilateral Subtrochanteric Femoral Fracture Related with Long-Term Biphosphonate Usage
Authors: ÖZTÜRK Recep , ATALAY İsmail , ÖZANLAĞAN Emre , ATEŞ Ömer , EKŞİOĞLU Mehmet
Published: May 2020

Bisphosphonates  are  widely 
used  in  the  treatment  of  osteoporosis. 
Bisphosphonates  act  via  suppression 
of  bone  resorption.Growing  numbers 
of  atypical  femur  fractures  have  been  reported  in  the  use  of  long-term 
bisphosphonates  in  recent 
years.In  this  case  report,  we  present  clinical 
presentation,  diagnosis, 
and  treatment  as  well  as  follow-up  of  a  60-year-old 
postmenopausal  female  patient 
who  had  metastatic 
breast  carcinoma,  with  bilateral  femoral 
subtrochanteric  fracture  associated 
with  long-term  use  of  bisphosphonates.

Frozen    species   
were   
sent    from    both   
fracture    lines,    as   
a    result    of   
the    frozen    examination,    no   
tumoral    tissue    was    found.    Proximal   
femoral    nail    to   
right    hiccup    and   
femur    proximal    anatomical    plaque   
to    left    hiccup   
were   
applied    in    the   
same    session.  The    patient    was    able   
to    walk    with   
full   
load    on    both   
lower    extremities,    and    there   
was    no    pain   
in    the    hip   
joint    movements    in   
the    rest    and   
exercise.
MORPHOMETRIC INVESTIGATION OF ANATOMIC STRUCTURES ON HUMERUS
Authors: YİLMAZ Seher , TOKPINAR Adem , TAŞTAN Mustafa , ATEŞ Şükrü , ÜNALMIŞ Demet , PATAT Dilara
Published: May 2020

Giriş: Humerus; Skapula, radius ve ulna kemikleri arasında bulunur ve üst ekstremitenin en uzun ve en kalın kemiğidir. Bu çalışma, cerrahi işlemler, ortez ve protez uygulamaları, humerusta morfometrik ve antropometrik ölçümler için bir kriter olacaktır.Gereç ve yöntem: Bu çalışma, 80 (56 sol, 24 sağ) kuru humerus kemik örneklerinde 0.01 milimetre (mm) hassasiyetinde dijital kumpas kullanılarak yapıldı. Kemik örneklerinde yaş ve cinsiyet ayrımı yapılmadı. Humerus üzerinde sulcus intertubercularis uzunluğu, minimum gövde çapı, maksimum gövde çapı, kapitulum humer, troclea humeri gibi 21 parametre ölçüldü.Bulgular: Çalışmamızın sonuçlarına göre humerusun maksimum uzunluğu (HMU); solda ortalama 31,16 ± 2,44 mm ve sağda 29,85 ± 3,08 mm. Minimum gövde çapı (MinGW); Solda 17,62 ± 2,18 mm ve sağda 17,84 ± 1,82 mm’dir.Sonuç: Humerus kemiğinin normal anatomik yapısını bilmek ve bu bölgedeki cerrahi prosedürleri ve protez uygulamalarını yönlendirmek için bu kemikteki anatomik yapıların ortalama değerlerini hesaplamak çok önemlidir.   Introduction: Humerus; It is located between the scapula, radius and ulna bones and is the longest and thickest bone of the upper extremity. This study will be a criterion for surgical procedures, orthosis and prosthesis applications, morphometric and anthropometric measurements on humerus.Materials and methods: This study was carried out using digital calipers with sensitivity of 0.01 millimeters (mm) on dry humerus bone specimens of 80 (56 left, 24 right). Age and sex were not differentiated in bone samples. Sulcus intertubercularis length, minimum trunk diameter, maximum trunk diameter, capitulum humer, troclea humer were measured on the humerus as 21 parameters.Results: According to the results of our study, the maximum length of the humerus (HMU); mean 31.16 ± 2.44 mm on the left and 29.85 ± 3.08 mm on the right. Minimum body diameter (MinGW); 17,62 ± 2,18 mm on the left and 17,84 ± 1,82 mm on the rightConclusion: It is very important to know the normal anatomical structure of the humerus bone and to calculate the average values ​​of the anatomical structures on this bone in order to guide the surgical procedures and prosthesis applications in this region.
MANAGEMENT OF ASPIRATION PNEUMONIA CASE OCCURED AFTER A SERIOUS POST-PARTUM HEMORRHAGE RELATED TO ANTICOAGULANT TREATMENT DURİNG PREGNANCY
Authors: BAŞER Emre , ONAT Taylan , DEMİR ÇALTEKİN Melike , AYDOĞAN KIRMIZI Demet , HİDAYET Şiho , KARA Mustafa , YALVAÇ Ethem Serdar
Published: May 2020

Life-long
anticoagulation therapy is mandatory in patients with mechanical heart valve to prevent the valve thrombosis.
It may cause teratogenic effects and hemorrhage complications in the pregnant
woman. In this report, we present a case who developed
post-partum haemorrhage related to anticoagulants and subsequently developed
aspiration pneumonia.