bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of Sexual Violence in Migrants, Applicants for International Protection, and Refugees in Europe: A Critical Interpretive Synthesis of the Evidence
Authors: De Schrijver Lotte , Vander Beken Tom , Krahé Barbara , Keygnaert Ines
Published: September 2018

(1) Background: Sexual violence (SV) is a major public health problem, with negative socio-economic, physical, mental, sexual, and reproductive health consequences. Migrants, applicants for international protection, and refugees (MARs) are vulnerable to SV. Since many European countries are seeing high migratory pressure, the development of prevention strategies and care paths focusing on victimised MARs is highly needed. To this end, this study reviews evidence on the prevalence of SV among MAR groups in Europe and the challenges encountered in research on this topic. (2) Methods: A critical interpretive synthesis of 25 peer-reviewed academic studies and 22 relevant grey literature documents was conducted based on a socio-ecological model. (3) Results: Evidence shows that SV is highly frequent in MARs in Europe, yet comparison with other groups is still difficult. Methodologically and ethically sound representative studies comparing between populations are still lacking. Challenges in researching SV in MARs are located at the intrapersonal, interpersonal, community, societal, and policy levels. (4) Conclusions: Future research should start with a clear definition of the concerned population and acts of SV to generate comparable data. Participatory qualitative research approaches could be applied to better grasp the complexity of interplaying determinants of SV in MARs.
The Change of Self-Rated Health According to Working Hours for Two Years by Gender
Authors: Ryu Jia , Yoon Yeogyeong , Kim Hyunjoo , Kang Chung won , Jung-Choi Kyunghee
Published: September 2018

Objective: The aim of this study was to confirm the association between working hours and self-rated health, and to find the degree of changes in health level by working hours according to gender. Methods: This study was based on the 929 workers (571 men and 358 women) from the Korean Labor and Income Panel Study during 2004–2006. To minimize the healthy worker effects, the study subjects included only those who did not have any chronic diseases, and who answered their health status as “moderate” or above in the baseline. Logistic regression analysis was used to confirm the associations between working hours and self-rated health. Results: In men, working hours per week of 47–52 h, 53–68 h, and >68 h were associated with 1.2, 1.3, and 1.1 times increases, respectively, in the odds ratio on worsened self-rated health, compared with the reference group (40–46 h). On the other hand, the risks were 1.0, 2.2, and 2.6 times increases in women. However, the results were different according to gender in the group with less than 40 h. The men with less than 40 h had a 0.9 times odds ratio on worsened self-rated health. For the women with less than 40 h, the odds ratio on self-rated health was 5.4 times higher than the reference group. Conclusions: Working more than 52 h per week had a negative effect on health, regardless of gender. However, in the group with less than 40 h, the negative association between working hours and self-rated health were shown only in women. Health outcomes due to working hours may differ by gender. Therefore, further studies are needed to explore the causes of these results.
The Cutaneous Microbiome and Wounds: New Molecular Targets to Promote Wound Healing
Authors: Johnson Taylor R. , Gómez Belinda I. , McIntyre Matthew K. , Dubick Michael A. , Christy Robert J. , Nicholson Susannah E. , Burmeister David M.
Published: September 2018

The ecological community of microorganisms in/on humans, termed the microbiome, is vital for sustaining homeostasis. While culture-independent techniques have revealed the role of the gut microbiome in human health and disease, the role of the cutaneous microbiome in wound healing is less defined. Skin commensals are essential in the maintenance of the epithelial barrier function, regulation of the host immune system, and protection from invading pathogenic microorganisms. In this review, we summarize the literature derived from pre-clinical and clinical studies on how changes in the microbiome of various acute and chronic skin wounds impact wound healing tissue regeneration. Furthermore, we review the mechanistic insights garnered from model wound healing systems. Finally, in the face of growing concern about antibiotic-resistance, we will discuss alternative strategies for the treatment of infected wounds to improve wound healing and outcomes. Taken together, it has become apparent that commensals, symbionts, and pathogens on human skin have an intimate role in the inflammatory response that highlights several potential strategies to treat infected, non-healing wounds. Despite these promising results, there are some contradictory and controversial findings from existing studies and more research is needed to define the role of the human skin microbiome in acute and chronic wound healing.
Characterization of the XTH Gene Family: New Insight to the Roles in Soybean Flooding Tolerance
Authors: Song Li , Valliyodan Babu , Prince Silvas , Wan Jinrong , Nguyen Henry T.
Published: September 2018

Xyloglucan endotransglycosylases/hydrolases (XTHs) are a class of enzymes involved in the construction and remodeling of cellulose/xyloglucan crosslinks and play an important role in regulating cell wall extensibility. However, little is known about this class of enzymes in soybean. Here, 61 soybean XTH genes (GmXTHs) were identified and classified into three subgroups through comparative phylogenetic analysis. Genome duplication greatly contributed to the expansion of GmXTH genes in soybean. A conserved amino acid motif responsible for the catalytic activity was identified in all GmXTHs. Further expression analysis revealed that most GmXTHs exhibited a distinct organ-specific expression pattern, and the expression level of many GmXTH genes was significantly associated with ethylene and flooding stress. To illustrate a possible role of XTH genes in regulating stress responses, the Arabidopsis AtXTH31 gene was overexpressed in soybean. The generated transgenic plants exhibited improved tolerance to flooding stress, with a higher germination rate and longer roots/hypocotyls during the seedling stage and vegetative growth stages. In summary, our combined bioinformatics and gene expression pattern analyses suggest that GmXTH genes play a role in regulating soybean stress responses. The enhanced soybean flooding tolerance resulting from the expression of an Arabidopsis XTH also supports the role of XTH genes in regulating plant flooding stress responses.
Lipoic Acid Prevents High-Fat Diet-Induced Hepatic Steatosis in Goto Kakizaki Rats by Reducing Oxidative Stress Through Nrf2 Activation
Authors: Sena Cristina Maria , Cipriano Maria Augusta , Botelho Maria Filomena , Seiça Raquel Maria
Published: September 2018

Prevention of hepatic fat accumulation may be an important approach for liver diseases due to the increased relevance of hepatic steatosis in this field. This study was conducted to investigate the effects of the antioxidant α-lipoic acid (α-LA) on hepatic steatosis, hepatocellular function, and oxidative stress in a model of type 2 diabetes fed with a high fat diet (HFD). Goto-Kakizaki rats were randomly divided into four groups. The first group received only a standard rat diet (control GK) including groups 2 (HFD), 3 (vehicle group), and 4 (α-LA group), which were given HFD, ad libitum during three months. Wistar rats are the non-diabetic control group. Carbohydrate and lipid metabolism, liver function, plasma and liver tissue malondialdehyde (MDA), liver GSH, tumor necrosis factor-α (TNF-α) and nuclear factor E2 (erythroid-derived 2)-related factor-2 (Nrf2) levels were assessed in the different groups. Liver function was assessed using quantitative hepatobiliary scintigraphy, serum aspartate, and alanine aminotransferases (AST, ALT), alkaline phosphatase, gamma-glutamyltranspeptidase, and bilirubin levels. Histopathologically steatosis and fibrosis were evaluated. Type 2 diabetic animals fed with HFD showed a marked hepatic steatosis and a diminished hepatic extraction fraction and both were fully prevented with α-LA. Plasma and liver tissue MDA and hepatic TNF-α levels were significantly higher in the HFD group when compared with the control group and significantly lower in the α-LA group. Systemic and hepatic cholesterol, triglycerides, and serum uric acid levels were higher in hyperlipidemic GK rats and fully prevented with α-LA. In addition, nuclear Nrf2 activity was significantly diminished in GK rats and significantly augmented after α-LA treatment. In conclusion, α-LA strikingly ameliorates steatosis in this animal model of diabetes fed with HFD by decrementing the inflammatory marker TNF-α and reducing oxidative stress. α-LA might be considered a useful therapeutic tool to prevent hepatic steatosis by incrementing antioxidant defense systems through Nrf2 and consequently decreasing oxidative stress and inflammation in type 2 diabetes.
Discovery of lahS as a Global Regulator of Environmental Adaptation and Virulence in Aeromonas hydrophila
Authors: Dong Yuhao , Wang Yao , Liu Jin , Ma Shuiyan , Awan Furqan , Lu Chengping , Liu Yongjie
Published: September 2018

Aeromonas hydrophila is an important aquatic microorganism that can cause fish hemorrhagic septicemia. In this study, we identified a novel LysR family transcriptional regulator (LahS) in the A. hydrophila Chinese epidemic strain NJ-35 from a library of 947 mutant strains. The deletion of lahS caused bacteria to exhibit significantly decreased hemolytic activity, motility, biofilm formation, protease production, and anti-bacterial competition ability when compared to the wild-type strain. In addition, the determination of the fifty percent lethal dose (LD50) in zebrafish demonstrated that the lahS deletion mutant (ΔlahS) was highly attenuated in virulence, with an approximately 200-fold increase in LD50 observed as compared with that of the wild-type strain. However, the ΔlahS strain exhibited significantly increased antioxidant activity (six-fold). Label-free quantitative proteome analysis resulted in the identification of 34 differentially expressed proteins in the ΔlahS strain. The differentially expressed proteins were involved in flagellum assembly, metabolism, redox reactions, and cell density induction. The data indicated that LahS might act as a global regulator to directly or indirectly regulate various biological processes in A. hydrophila NJ-35, contributing to a greater understanding the pathogenic mechanisms of A. hydrophila.
CRISPR/Cas9-Mediated Multiplex Genome Editing of the BnWRKY11 and BnWRKY70 Genes in Brassica napus L.
Authors: Sun Qinfu , Lin Li , Liu Dongxiao , Wu Dewei , Fang Yujie , Wu Jian , Wang Youping
Published: September 2018

Targeted genome editing is a desirable means of basic science and crop improvement. The clustered, regularly interspaced, palindromic repeat (CRISPR)/Cas9 (CRISPR-associated 9) system is currently the simplest and most commonly used system in targeted genomic editing in plants. Single and multiplex genome editing in plants can be achieved under this system. In Arabidopsis, AtWRKY11 and AtWRKY70 genes were involved in JA- and SA-induced resistance to pathogens, in rapeseed (Brassica napus L.), BnWRKY11 and BnWRKY70 genes were found to be differently expressed after inoculated with the pathogenic fungus, Sclerotinia sclerotiorum (Lib.) de Bary. In this study, two Cas9/sgRNA constructs targeting two copies of BnWRKY11 and four copies of BnWRKY70 were designed to generate BnWRKY11 and BnWRKY70 mutants respectively. As a result, twenty-two BnWRKY11 and eight BnWRKY70 independent transformants (T0) were obtained, with the mutation ratios of 54.5% (12/22) and 50% (4/8) in BnWRKY11 and BnWRKY70 transformants respectively. Eight and two plants with two copies of mutated BnWRKY11 and BnWRKY70 were obtained respectively. In T1 generation of each plant examined, new mutations on target genes were detected with high efficiency. The vast majority of BnWRKY70 mutants showed editing in three copies of BnWRKY70 in examined T1 plants. BnWRKY70 mutants exhibited enhanced resistance to Sclerotinia, while BnWRKY11 mutants showed no significant difference in Sclerotinia resistance when compared to non-transgenic plants. In addition, plants that overexpressed BnWRKY70 showed increased sensitivity when compared to non-transgenic plants. Altogether, our results demonstrated that BnWRKY70 may function as a regulating factor to negatively control the Sclerotinia resistance and CRISPR/Cas9 system could be used to generate germplasm in B. napus with high resistance against Sclerotinia.
Comparison of Cytomorphometry and Early Cell Response of Human Gingival Fibroblast (HGFs) between Zirconium and New Zirconia-Reinforced Lithium Silicate Ceramics (ZLS)
Authors: Rizo-Gorrita María , Luna-Oliva Irene , Serrera-Figallo María-Ángeles , Gutiérrez-Pérez José-Luis , Torres-Lagares Daniel
Published: September 2018

New zirconia-reinforced lithium silicate ceramics (ZLS) could be a viable alternative to zirconium (Y-TZP) in the manufacture of implantological abutments—especially in aesthetic cases—due to its good mechanical, optical, and biocompatibility properties. Although there are several studies on the ZLS mechanical properties, there are no studies regarding proliferation, spreading, or cytomorphometry. We designed the present study which compares the surface, cellular proliferation, and cellular morphology between Y-TZP (Vita YZ® T [Vita Zahnfabrik (Postfach, Germany)]) and ZLS (Celtra® Duo [Degudent (Hanau-Wolfgang, Germany)]). The surface characterization was performed with energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), and optical profilometry. Human gingival fibroblasts (HGFs) were subsequently cultured on both materials and early cellular response and cell morphology were compared through nuclear and cytoskeletal measurement parameters using confocal microscopy. The results showed greater proliferation and spreading on the surface of Y-TZP. This could indicate that Y-TZP continues to be a gold standard in terms of transgingival implant material: Nevertheless, more in vitro and in vivo research is necessary to confirm the results obtained in this study.
Metabolic Profile and Myocardial Performance of Renal Transplant Recipients Participating in Unsupervised Physical Exercise as a Prescription Program
Authors: Moscarelli Luciano , Sofi Francesco , Mascherini Gabriele , Bini Vittorio , Ingletto Chiara , Mandoli Marco , Galanti Giorgio , Stefani Laura
Published: September 2018

Introduction: Renal transplant recipients (RTRs) are at high cardiovascular risk (CV) compared to the general population, especially after surgical treatment. The literature supports the role of supervised exercise intervention; however no data are available regarding the effects of unsupervised exercise programs. We investigated whether a home exercise program could reduce CV risk in RTR based on possible changes in renal and cardiometabolic parameters and myocardial performance measured by echocardiography. Methods: From a large cohort of 60 RTRs, 30 RTRs (12 females and 18 males 48.3 ± 12.3 years) participated in individualized and unsupervised training programs for 6 months, at moderate intensity. Cardiometabolic risk factors, anthropometric parameters, lipid and glycemic blood sample profiles were studied as was myocardial performance from the 2D echo examination at T0, and T6 months. Results: The lipid profile remained in the range of a low level of risk, although there was no significant improvement, whereas myocardial performance, in particular the EF, was significantly improved. Conclusions: A home exercise program for at least 6 months produces positive effects on myocardial function and helps maintain a low cardiovascular risk profile. The trend supports the importance of highlighting the role of a correct reconditioning of lifestyle in RTR, from the exercise program without supervision to moderate intensity, where well tolerated.
Evaluating Logistics Performances of Agricultural Prunings for Energy Production: A Logistics Audit Analysis Approach
Authors: Bosona Techane , Gebresenbet Girma
Published: September 2018

The utilization of agricultural prunings as renewable energy sources requires effective and efficient logistics systems. The objective of this paper was to map out logistics activities along the agricultural pruning-to-energy (PtE) value chains. It describes the logistics performances based on the existing and potential pruning biomass supply chains focusing on prunings from fruit tree, vineyards, olive groove, and up-rooted tree branches. A logistics audit analysis approach has been used for detailed assessment of logistics performances. The analysis was based mainly on primary data gathered using a structured data survey format targeting the existing and potential PtE initiatives in Spain, Germany, Denmark, France, and Poland. The analysis considered the major stages of the chain, such as pruning, harvesting, processing (e.g., baling and chipping), storage, transport, and the linkage between the different stages. The paper identified the constraints along the logistics chain and recommended appropriate interventions to promote the marketing of agricultural pruning focusing on the supply of quality bales and chips for renewable energy production, and to increase the sustainability of renewable energy generation from PtE initiatives. The study has indicated that there are economic, social, and environmental benefits of PtE initiatives, as well as opportunities to increase the implementation and sustainability of the system.
Examples from Blockchain Implementations in Logistics and Supply Chain Management: Exploring the Mindful Use of a New Technology
Authors: Verhoeven Peter , Sinn Florian , Herden Tino T.
Published: September 2018

In the context of logistics, blockchain can help to increase end-to-end visibility along global supply chains. Thus, it can lead to improved tracking of goods and offer tamper-proof data to build trust among parties. Although a variety of blockchain use cases already exists, not all of them seem to rely on blockchain-specific features, but could rather be solved with traditional technologies. The purpose of this paper is, therefore, to identify characteristic use cases described for blockchain in the field of LSCM and to analyze them regarding their mindful technology use based on five mindful technology adoption principles: engagement with the technology; Technological novelty seeking; awareness of local context; cognizance of alternative technologies; and anticipation of technology alteration. The authors identified five blockchain case clusters and chose one case for each category to be analyzed in detail. Most cases demonstrate high engagement with the technology, but there are significant differences when it comes to the other mindful use principles. This paper highlights the need to understand the problem and to apply the right technology in order to solve it. When solving a problem, care should be taken to address a technology’s unique features to ensure effectiveness and cost-efficiency.
5-Amino-3-(diethylamino)-5H-benzo[4,5]imidazo[1,2-b][1,2,4,6]thiatriazine 1,1-Dioxide
Authors: Tran Victor , Forsyth Craig , Francis Craig
Published: September 2018

In the quest for discovery of novel bioactive molecules, new heterocyclic ring systems provide templates for exploration of uncharted chemical space. Herein, we describe the synthesis of a new benzo[4,5]imidazo[1,2-b][1,2,4,6]thiatriazine derivative from readily available 1,2-diaminobenzimidazole and N,N-diethyl-N′-chlorosulfonyl chloroformamidine. The product structure, confirmed by X-ray crystallography, bears an exocyclic NH2 group, which should enable synthesis of an extended range of derivatives of this unusual scaffold.
A Co-Polarization Broadband Radar Absorber for RCS Reduction
Authors: Beeharry Thtreswar , Yahiaoui Riad , Selemani Kamardine , Ouslimani Habiba Hafdallah
Published: September 2018

In this article, a single layer co-polarization broadband radar absorber is presented. Under normal incidence, it achieves at least 90% of absorption from 5.6 GHz to 9.1 GHz for both Transverse Electric (TE) and Transverse Magnetic (TM) polarizations. Our contribution and the challenge of this work is to achieve broadband absorption using a very thin single layer dielectric and it is achieved by rotating the resonating element by 45°. An original optimized Underlined U shape has been developed for the resonating element which provides a broadband co-polarization absorption. The structure is 12.7 times thinner than the wavelength at the center frequency. To understand the absorption mechanism, the transmission line model of an absorber and the three near unity absorption peaks at 5.87 GHz, 7.16 GHz and 8.82 GHz have been used to study the electric and magnetic fields. The physical insight of how the three near unity absorption peaks are achieved has also been discussed. After fabricating the structure, the measurements were found to be in good agreement with the simulation results. Furthermore, with the proposed original UUSR resonating element, the operational bandwidth to thickness ratio of 6.43 is obtained making the proposed UUSR very competitive.
Control of Biofilm Formation in Healthcare: Recent Advances Exploiting Quorum-Sensing Interference Strategies and Multidrug Efflux Pump Inhibitors
Authors: Subhadra Bindu , Kim Dong Ho , Woo Kyungho , Surendran Surya , Choi Chul Hee
Published: September 2018

Biofilm formation in healthcare is an issue of considerable concern, as it results in increased morbidity and mortality, imposing a significant financial burden on the healthcare system. Biofilms are highly resistant to conventional antimicrobial therapies and lead to persistent infections. Hence, there is a high demand for novel strategies other than conventional antibiotic therapies to control biofilm-based infections. There are two approaches which have been employed so far to control biofilm formation in healthcare settings: one is the development of biofilm inhibitors based on the understanding of the molecular mechanism of biofilm formation, and the other is to modify the biomaterials which are used in medical devices to prevent biofilm formation. This review will focus on the recent advances in anti-biofilm approaches by interrupting the quorum-sensing cellular communication system and the multidrug efflux pumps which play an important role in biofilm formation. Research efforts directed towards these promising strategies could eventually lead to the development of better anti-biofilm therapies than the conventional treatments.
Microstructure and Properties of Mg-Zn-Y Alloy Powder Compacted by Equal Channel Angular Pressing
Authors: Chiu Chun , Huang Hong-Min
Published: September 2018

Mg97Zn1Y2 (at %) alloy with a long period stacking ordered (LPSO) phase has attracted a great deal of attention due to its excellent mechanical properties. It has been reported that this alloy could be fabricated by warm extrusion of rapid solidified alloy powders. In this study, an alternative route combining mechanical milling and equal channel angular pressing (ECAP) was selected to produce the bulk Mg97Zn1Y2 alloy. Microstructural characterization, mechanical properties and corrosion behavior of the ECAP-compacted alloys were studied. The as-cast alloy contained α-Mg and LPSO-Mg12Zn1Y1 phase. In the as-milled powder, the LPSO phase decomposed and formed Mg24Y5 phase. The ECAP-compacted alloy had identical phases to those of the as-milled sample. The compacted alloy exhibited a hardness of 120 HV and a compressive yield strength of 308 MPa, which were higher than those of the as-cast counterpart. The compacted alloy had better corrosion resistance, which was attributed to the reduced volume fraction of the secondary phase resulting in lower microgalvanic corrosion in the compacted alloy. The increase in Y content in the α-Mg matrix also contributed to the improvement of corrosion resistance.
Pyropia yezoensis Protein Supplementation Prevents Dexamethasone-Induced Muscle Atrophy in C57BL/6 Mice
Authors: Lee Min-Kyeong , Choi Jeong-Wook , Choi Youn Hee , Nam Taek-Jeong
Published: September 2018

We investigated the protective effects of Pyropia yezoensis crude protein (PYCP) against dexamethasone (DEX)-induced myotube atrophy and its underlying mechanisms. DEX (3 mg/kg body weight, intraperitoneal injection) and PYCP (150 and 300 mg/kg body weight, oral) were administrated to mice for 18 days, and the effects of PYCP on DEX-induced muscle atrophy were evaluated. Body weight, calf thickness, and gastrocnemius and tibialis anterior muscle weight were significantly decreased by DEX administration (p < 0.05), while PYCP supplementation effectively prevented the DEX-induced decrease in body weight, calf thickness, and muscle weight. PYCP supplementation also attenuated the DEX-induced increase in serum glucose, creatine kinase, and lactate dehydrogenase levels. Additionally, PYCP supplementation reversed DEX-induced muscle atrophy via the regulation of the insulin-like growth factor-I/protein kinase B/rapamycin-sensitive mTOR complex I/forkhead box O signaling pathway. The mechanistic investigation revealed that PYCP inhibited the ubiquitin-proteasome and autophagy-lysosome pathways in DEX-administrated C57BL/6 mice. These findings demonstrated that PYCP increased protein synthesis and decreased protein breakdown to prevent muscle atrophy. Therefore, PYCP supplementation appears to be useful for preventing muscle atrophy.
Introduction to Photonics: Principles and the Most Recent Applications of Microstructures
Authors: Amiri Iraj Sadegh , Azzuhri Saaidal Razalli Bin , Jalil Muhammad Arif , Hairi Haryana Mohd , Ali Jalil , Bunruangses Montree , Yupapin Preecha
Published: September 2018

Light has found applications in data transmission, such as optical fibers and waveguides and in optoelectronics. It consists of a series of electromagnetic waves, with particle behavior. Photonics involves the proper use of light as a tool for the benefit of humans. It is derived from the root word “photon”, which connotes the tiniest entity of light analogous to an electron in electricity. Photonics have a broad range of scientific and technological applications that are practically limitless and include medical diagnostics, organic synthesis, communications, as well as fusion energy. This will enhance the quality of life in many areas such as communications and information technology, advanced manufacturing, defense, health, medicine, and energy. The signal transmission methods used in wireless photonic systems are digital baseband and RoF (Radio-over-Fiber) optical communication. Microwave photonics is considered to be one of the emerging research fields. The mid infrared (mid-IR) spectroscopy offers a principal means for biological structure analysis as well as nonintrusive measurements. There is a lower loss in the propagations involving waveguides. Waveguides have simple structures and are cost-efficient in comparison with optical fibers. These are important components due to their compactness, low profile, and many advantages over conventional metallic waveguides. Among the waveguides, optofluidic waveguides have been found to provide a very powerful foundation for building optofluidic sensors. These can be used to fabricate the biosensors based on fluorescence. In an optical fiber, the evanescent field excitation is employed to sense the environmental refractive index changes. Optical fibers as waveguides can be used as sensors to measure strain, temperature, pressure, displacements, vibrations, and other quantities by modifying a fiber. For some application areas, however, fiber-optic sensors are increasingly recognized as a technology with very interesting possibilities. In this review, we present the most common and recent applications of the optical fiber-based sensors. These kinds of sensors can be fabricated by a modification of the waveguide structures to enhance the evanescent field; therefore, direct interactions of the measurand with electromagnetic waves can be performed. In this research, the most recent applications of photonics components are studied and discussed.
Comparison of Physicochemical Properties of Starches from Flesh and Peel of Green Banana Fruit
Authors: Li Zheng , Guo Ke , Lin Lingshang , He Wei , Zhang Long , Wei Cunxu
Published: September 2018

Green banana fruit is an important starch resource that consists of flesh and peel. The physicochemical properties of flesh starch have been widely studied; however, those of peel starch have hardly been studied, leading to the waste of peel. In this study, the physicochemical properties of the starches from the flesh and peel of green banana fruit were investigated and compared. The dry flesh and peel had 69.5% and 22.6% starch content, respectively. The starch had oval and irregular granules with eccentric hila. Their starches had similar bimodal size distribution; the volume-weighted mean diameter was approximate 17 μm, and the peel starch had a slightly smaller granule size than the flesh starch. The maximum absorption wavelength was higher in peel starch than in flesh starch. The apparent amylose content of flesh and peel starch was 21.3% and 25.7%, respectively. The flesh and peel starches both exhibited B-type crystalline structures and had similar relative crystallinity, short-range ordered degrees, and lamellar structures. The swelling power was similar between flesh and peel starches, but the water solubility was higher in peel starch than in flesh starch at 95 °C. The peel starch had a higher gelatinization temperature than flesh starch, but their gelatinization temperature range and enthalpy were similar. Both flesh and peel starches showed a diphasic hydrolysis dynamic, but peel starch had higher resistance to porcine pancreatic α-amylase hydrolysis than flesh starch. The contents of rapidly digestible starch, slowly digestible starch, and the resistant starch of flesh and peel were 1.7%, 4.3%, 94.1% and 1.4%, 3.4%, 95.2%, respectively, for native starch, and 73.0%, 5.1%, 21.9%, and 72.3%, 4.5%, 23.2%, respectively, for gelatinized starch.
The Role of Heavy Metals in Plant Response to Biotic Stress
Authors: Morkunas Iwona , Woźniak Agnieszka , Mai Van Chung , Rucińska-Sobkowiak Renata , Jeandet Philippe
Published: September 2018

The present review discusses the impact of heavy metals on the growth of plants at different concentrations, paying particular attention to the hormesis effect. Within the past decade, study of the hormesis phenomenon has generated considerable interest because it was considered not only in the framework of plant growth stimulation but also as an adaptive response of plants to a low level of stress which in turn can play an important role in their responses to other stress factors. In this review, we focused on the defence mechanisms of plants as a response to different metal ion doses and during the crosstalk between metal ions and biotic stressors such as insects and pathogenic fungi. Issues relating to metal ion acquisition and ion homeostasis that may be essential for the survival of plants, pathogens and herbivores competing in the same environment were highlighted. Besides, the influence of heavy metals on insects, especially aphids and pathogenic fungi, was shown. Our intention was also to shed light on the relationship between heavy metals deposition in the environment and ecological communities formed under a strong selective pressure.
Digital Cultural Heritage
Authors: Portalés Cristina , Rodrigues João M. F. , Rodrigues Gonçalves Alexandra , Alba Ester , Sebastián Jorge
Published: September 2018

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Aptamers as Diagnostic Tools in Cancer
Authors: Ruiz Ciancio Dario , Vargas Mauricio R. , Thiel William H. , Bruno Martin A. , Giangrande Paloma H. , Mestre María Belén
Published: September 2018

Cancer is the second leading cause of death worldwide. Researchers have been working hard on investigating not only improved therapeutics but also on early detection methods, both critical to increasing treatment efficacy, and developing methods for disease prevention. The use of nucleic acids, or aptamers, has emerged as more specific and accurate cancer diagnostic and therapeutic tools. Aptamers are single-stranded DNA or RNA molecules that recognize specific targets based on unique three-dimensional conformations. Despite the fact aptamer development has been mainly restricted to laboratory settings, the unique attributes of these molecules suggest their high potential for clinical advances in cancer detection. Aptamers can be selected for a wide range of targets, and also linked with an extensive variety of diagnostic agents, via physical or chemical conjugation, to improve previously-established detection methods or to be used as novel biosensors for cancer diagnosis. Consequently, herein we review the principal considerations and recent updates in cancer detection and imaging through aptamer-based molecules.
Life Cycle and Genetic Diversity of Symplocarpus nipponicus (Araceae), an Endangered Species in Japan
Authors: Takeda Seiji , Onishi Yusuke , Fukui Yoshio , Ohsako Takanori , Kubo Nakao
Published: September 2018

Symplocarpus nipponicus, a member of the Araceae family, is an endangered plant in several prefectures in Japan. For the conservation of this wild species, we investigated the morphology, life cycle, and genetic diversity of three wild populations. By fixed-point observation over several years, we found that it takes at least four years for the plant to set the inflorescences consisting of spadices and spathes, and another two years for it to set mature seeds. To examine the genetic diversity in the wild population, we developed 11 novel microsatellite markers and investigated the genetic variation in three populations in Kyoto Prefecture: Ayabe, Hanase, and Momoi. The Ayabe population carried less genetic variation than the other two areas, suggesting the isolation of the habitat and thus a higher risk of extinction. Our results provide basic knowledge of the ecological aspects of S. nipponicus, as well as molecular techniques for the assessment of its genetic diversity, and thus are useful for the conservation of this endangered species.
High Pressure Treatment for Improving Water Vapour Barrier Properties of Poly(lactic acid)/Ag Nanocomposite Films
Authors: Chi Hai , Xue Jing , Zhang Cheng , Chen Haiyan , Li Lin , Qin Yuyue
Published: September 2018

Effects of high pressure treatment (0, 200 and 400 MPa) on water vapour barrier, microstructure, thermal, and mechanical properties of poly (lactic acid) (PLA)/Ag nanocomposite films were investigated. The migration behavior of nano-Ag from the nanocomposite films in the presence of 50% (v/v) ethanol as a food simulant was also studied. The water vapour barrier properties increased as pressure was applied to film-forming solutions. High pressure treatment enhanced the mutual effect between PLA and nanoparticles, leading to a more compact network structure in PLA/Ag nanocomposite films. Furthermore, PLA/Ag nanocomposite films treated by high pressure were significantly affected by microstructure, thermal, and mechanical properties when, compared with untreated samples. High pressure treatment at 200 to 400 MPa significantly (p < 0.05) reduced the migration of nano-Ag from the films. Overall, high pressure treatment on film-forming solutions showed potential in improving the functional properties of nanocomposite films, especially in relation to water vapour barrier properties.
Sponge-Like Water De-/Ad-Sorption versus Solid-State Structural Transformation and Colour-Changing Behavior of an Entangled 3D Composite Supramolecuar Architecture, [Ni4(dpe)4(btc)2(Hbtc)(H2O)9]·3H2O
Authors: Wang Chih-Chieh , Ke Szu-Yu , Chen Kuan-Ting , Sun Ning-Kuei , Liu Wei-Fang , Ho Mei-Lin , Lu Bing-Jyun , Hsieh Yi-Ting , Chuang Yu-Chun , Lee Gene-Hsiang , Huang Shi-Yi , Yang En-Che
Published: September 2018

An entangled composite compound, [Ni4(dpe)4(btc)2(Hbtc)(H2O)9]·3H2O (1), where H3btc = 1,3,5-benzenetricarboxylic acid and dpe = 1,2-bis(4-pyridyl)ethane, has been synthesized and structurally characterized. Single-crystal structural determination reveals that compound 1 consists of four coordination polymers (CPs), with two two-dimensional (2D) (4,4) layered metal-organic frameworks (MOFs) of [Ni(dpe)(Hbtc)(H2O)] and [Ni(dpe)(btc)(H2O)]− anion, and two one-dimensional (1D) polymeric chains of [Ni(dpe)(btc)(H2O)3]− anion and [Ni(dpe)(H2O)4]2+ cation, respectively. The three-dimensional (3D) supramolecular architecture of 1 is constructed via the inter-penetration of inter-digited, double-layered, 2D rectangle-grid MOFs by two 1D coordination polymeric chains, and tightly entangled together via the combination of inter-CPs π–π stacking and hydrogen bonding interactions. The ad-/de-sorption isotherms of 1 for water displays a hysteresis profile with a maximum adsorption of 17.66 water molecules of per molecule unit at relative P/P0 < 0.89. The reversible de-/re-hydration processes in 1 monitored by cyclic water de-/ad-sorption TG analysis and PXRD measurements evidence a sponge-like water de-/ad-sorption property associated with a thermal-induced solid-state structural transformation. The magnetic property of 1 suggests that the ferromagnetic coupling might refer to a stronger inter-Ni(II) interaction, which could be along the btc3− or Hbtc2− ligands; the antiferromagnetic coupling corresponding to the weaker inter-Ni(II) interactions, which could be the dpe ligands for the 2D framework.
A Description of Two New Species of the Genus Rucervus (Cervidae, Mammalia) from the Early Pleistocene of Southeast Europe, with Comments on Hominin and South Asian Ruminants Dispersals
Authors: Croitor Roman
Published: September 2018

The article attests the presence of the genus Rucervus in the paleontological record of Europe and presents the description of new species of large-sized deer Rucervus radulescui sp. nov. from the Early Pleistocene of Valea Grăunceanului (Southern Romania) and Rucervus gigans sp. nov. from the late Early Pleistocene of Apollonia-1 (Greece). The described cervid species represent two different evolutionary radiations of Rucervus that are grouped into the extinct subgenus Arvernoceros that represents the northern evolutionary radiation and the nominotypical subgenus that is regarded as the southern evolutionary radiation and represented today by only one species Rucervus duvaucelii. The evolutionary radiation and dispersals of Rucervus are regarded in the paleobiogeographic context of faunal exchanges between southeastern Europe, Caucasus, and Near East during the Early Pleistocene and the westward dispersal of early hominins in Eurasia.
Animal Ethics in Islam: A Review Article
Authors: Tlili Sarra
Published: September 2018

This article offers an assessment of the current state of scholarship on animal ethics in Islam. It first discusses a group of texts that share the preoccupation of demonstrating the superiority of Islam’s animal teachings, thus exhibiting a clearly apologetic tone. Then it turns to the debate on animal ethics in Western academia. By raising challenging questions, the latter holds the promise of delving deeper into the subject, but at its current stage much of it is still hampered by factual inaccuracies and methodological flaws. In conclusion, the article explains why the subject of animal ethics in Islam is particularly deserving of careful study.
Review and Characterization of Portuguese Theses, Dissertations, and Papers about Spirituality in Health
Authors: Romeiro Joana , Martins Helga , Pinto Sara , Caldeira Sílvia
Published: September 2018

Research about spirituality has grown widely in the past decades and the interest in health care is also evident in Portugal. This literature review aims to identify and to characterize Portuguese theses, dissertations, and papers about spirituality in health, and to provide a systematic overview of the knowledge concerning this subject. The search was conducted in February 2017 and updated in January 2018. Four independent reviewers screened and analyzed all citations, and a total of 76 results were included. Publications started in 2002 and include master degree dissertations (n = 37), scientific papers (n = 31), and PhD theses (n = 8). Papers were published in 24 national and international journals. Most papers were psychology- and nursing-related and had a quantitative design (n = 55). Samples were mostly composed of patients living with a chronic disease (n = 20) or elderly (n = 11). The Spiritual Well-Being Questionnaire (SWBQ) was the most used tool. A multidisciplinary approach is regarded as foundational in implementing spirituality in the provision of health care and the results underline the interest on this topic from other disciplines rather than nursing. Further studies must provide a deeper understanding of spirituality in children, adolescents or families’ perspective bringing new insights to advanced health practice.
Quantitative Responses of Satellite-Derived Nighttime Lighting Signals to Anthropogenic Land-Use and Land-Cover Changes across China
Authors: Ma Ting
Published: September 2018

Remotely sensed artificial lighting radiances at night can provide spatially explicit proxy measures of the magnitude of human activity. Satellite-derived nighttime light images, mainly provided by the Defense Meteorological Satellite Program (DMSP) and the Visible Infrared Imaging Radiometer Suite (VIIRS) day/night band (DNB), have been increasingly used to study demographic and socioeconomic activities for a wide range of issues—for instance, human population dynamics, economic growth, and urbanization process—at multiple scales. In practice, the lack of texture information regarding man-made surfaces would usually lead to substantial difficulty in delineating the spatial dynamics in human settlements due to the diverse distributions of artificial nocturnal lighting sources, which are closely related to the predominant land-use/land-cover (LULC) types and their evolutions. An understanding of how nighttime lighting signals respond to synchronous anthropogenic LULC changes, therefore, is crucially important for the spatiotemporal investigations of human settlement dynamics. In this study, we used DMSP-derived nighttime light (NTL) data and Landsat-derived LULC maps to quantitatively estimate the pixel-level responses of NTL signals to different types of human-induced LULC conversions between 1995 and 2010 across China. Our results suggest that the majority (>70%) of pixel-level LULC conversions into artificial lands (including urban, rural, and built-up lands) might show a statistically significant increase in nighttime brightness with an average >20 (in digital number, DN) step change in nighttime lights (dNTL), both of which are distinctly higher than that in the LULC conversions into non-man-made surfaces on the whole. A receiver operating characteristic (ROC) curve-based analysis implies that we might have an average chance of ~90% to identify the nationwide LULC conversions into man-made surfaces from all types of conversions through the observed changes in artificial nocturnal luminosity signals. Moreover, ROC curve-based analyses also yield two nation-level optimal dNTL thresholds of 4.8 and 7.8 DN for recognizing newly emerged three types of artificial lands and urban lands between 1995 and 2010 across the entire country, respectively. In short, our findings reveal fundamental insights into the quantitative connections between the anthropogenic LULC changes and the corresponding responses of synchronous nightlight signals at the pixel-level, which are generally essential for further applications of satellite-derived nocturnal luminosity data in the spatiotemporal investigations of human settlement dynamics.
Modelling the L-Band Snow-Covered Surface Emission in a Winter Canadian Prairie Environment
Authors: Roy Alexandre , Leduc-Leballeur Marion , Picard Ghislain , Royer Alain , Toose Peter , Derksen Chris , Lemmetyinen Juha , Berg Aaron , Rowlandson Tracy , Schwank Mike
Published: September 2018

Detailed angular ground-based L-band brightness temperature (TB) measurements over snow covered frozen soil in a prairie environment were used to parameterize and evaluate an electromagnetic model, the Wave Approach for LOw-frequency MIcrowave emission in Snow (WALOMIS), for seasonal snow. WALOMIS, initially developed for Antarctic applications, was extended with a soil interface model. A Gaussian noise on snow layer thickness was implemented to account for natural variability and thus improve the TB simulations compared to observations. The model performance was compared with two radiative transfer models, the Dense Media Radiative Transfer-Multi Layer incoherent model (DMRT-ML) and a version of the Microwave Emission Model for Layered Snowpacks (MEMLS) adapted specifically for use at L-band in the original one-layer configuration (LS-MEMLS-1L). Angular radiometer measurements (30°, 40°, 50°, and 60°) were acquired at six snow pits. The root-mean-square error (RMSE) between simulated and measured TB at vertical and horizontal polarizations were similar for the three models, with overall RMSE between 7.2 and 10.5 K. However, WALOMIS and DMRT-ML were able to better reproduce the observed TB at higher incidence angles (50° and 60°) and at horizontal polarization. The similar results obtained between WALOMIS and DMRT-ML suggests that the interference phenomena are weak in the case of shallow seasonal snow despite the presence of visible layers with thicknesses smaller than the wavelength, and the radiative transfer model can thus be used to compute L-band brightness temperature.
Mesoscale Resolution Radar Data Assimilation Experiments with the Harmonie Model
Authors: Ivanov Serguei , Michaelides Silas , Ruban Igor
Published: September 2018

This study presents a pre-processing approach adopted for the radar reflectivity data assimilation and results of simulations with the Harmonie numerical weather prediction model. The proposed method creates a 3D regular grid in which a horizontal size of meshes coincides with the horizontal model resolution. This minimizes the representative error associated with the discrepancy between resolutions of informational sources. After such preprocessing, horizontal structure functions and their gradients for radar reflectivity maintain the sizes and shapes of precipitation patterns similar to those of the original data. The method shows an improvement of precipitation prediction within the radar location area in both the rain rates and spatial pattern presentation. It redistributes precipitable water with smoothed values over the common domain since the control runs show, among several sub-domains with increased and decreased values, correspondingly. It also reproduces the mesoscale belts and cell patterns of sizes from a few to ten kilometers in precipitation fields. With the assimilation of radar data, the model simulates larger water content in the middle troposphere within the layer from 1 km to 6 km with major variations at 2.5 km to 3 km. It also reproduces the mesoscale belt and cell patterns of precipitation fields.