bluuebunny/crossref_metadata_2025 huggingface dataset:
Internet-Based Patient Education Materials Regarding Diabetic Foot Ulcers: Readability and Quality Assessment (Preprint)
Authors: Lee David Michael , Grose Elysia , Cross Karen
Published: January 2021

BACKGROUND

While diabetic foot ulcers (DFU) are a common complication of diabetes, little is known about the content and readability of online patient education materials (PEM) for DFU. The recommended reading grade level for these materials is grades 6-8.

OBJECTIVE

The aim of this paper was to evaluate the quality and readability of online PEM on DFU.

METHODS

A Google search was performed using 4 different search terms related to DFU. Two readability formulas were used to assess the readability of the included PEM. These included the Flesch-Kincaid grade level and the Flesch-Reading ease score. The DISCERN tool was used to determine quality and reliability.

RESULTS

A total of 41 online PEM were included. The average Flesch-Reading ease score for all PEM was 63.43 (SD 14.21), indicating a standard difficulty level of reading. The average reading grade level was 7.85 (SD 2.38), which is higher than the recommended reading level for PEM. The mean DISCERN score was 45.66 (SD 3.34), and 27% (11/41) of the articles had DISCERN scores of less than 39, corresponding to poor or very poor quality.

CONCLUSIONS

The majority of online PEM on DFU are written above the recommended reading levels and have significant deficiencies in quality and reliability. Clinicians and patients should be aware of the shortcomings of these resources and consider the impact they may have on patients’ self-management.
Risk Factors Associated with a Dengue Fever Outbreak in Islamabad, Pakistan: Case-Control Study (Preprint)
Authors: Mehmood Amjad , Khalid Khan Fawad , Chaudhry Ambreen , Hussain Zakir , Laghari Mumtaz Ali , Shah Ijaz , Baig Zeeshan Iqbal , Baig Mirza Amir , Khader Yousef , Ikram Aamer
Published: January 2021

BACKGROUND

On October 23, 2016, 79 dengue fever cases were reported from the Union Council Tarlai to Federal Disease Surveillance and Response Unit Islamabad. A team was established to investigate the suspected dengue outbreak.

OBJECTIVE

The aim of this study was to determine the extent of the outbreak and identify the possible risk factors.

METHODS

Active case finding was performed through a house-to-house survey. A case was defined as an acute onset of fever ≥38℃ in a resident of Tarlai from October 2 to November 11, 2016, with a positive dengue virus (nonstructural protein, NS-1) test and any of the two of following signs and symptoms: retroorbital/ocular pain, headache, rash, myalgia, arthralgia, and hemorrhagic manifestations. A structured questionnaire was used to collect data. Age- and sex-matched controls (1:1) were identified from residents in the same area as cases. Blood samples were taken and sent to the National Institute of Health for genotype identification.

RESULTS

During the active case search, 145 cases of dengue fever were identified by surveying 928 houses from October 23 to November 11, 2016. The attack rate (AR) was 17.0/10,000. The mean age was 34.4 (SD 14.4) years. More than half of the cases were male (80/145, 55.2%). Among all cases, 29% belonged to the 25-34 years age group and the highest AR was found in the 35-44 years age group (35.6/10,000), followed by the 55-64 years age group (35.5/10,000). All five blood samples tested positive for NS-1 (genotype DENV-2). The most frequent presenting signs/symptoms were fever and headache (both 100%). Stagnant water around houses (odds ratio [OR] 4.86, 95% CI 2.94-8.01; P<.001), presence of flower pots in the home (OR 2.73, 95% CI 1.67-4.45; P<.001), and open water containers (OR 2.24, 95% CI 1.36-3.60; P<.001) showed higher odds among cases. Conversely, use of bed nets (OR 0.44, 95% CI 0.25-0.77; P=.003), insecticidal spray (OR 0.33, 95% CI 0.22-0.55; P<.001), door screens (OR 0.27, 95% CI 0.15-0.46; P<.001), mosquito coil/mat (OR 0.26, 95% CI 0.16-0.44; P<.001), and cleanliness of the house (OR 0.12, 95% CI 0.05-0.26; P<.001) showed significant protective effects.

CONCLUSIONS

Stagnant water acting as breeding grounds for vectors was identified as the probable cause of spread of the dengue outbreak. Establishment of surveillance and an early reporting system along with use of protective measures against the vector are strongly recommended.
Risk Factors of Dengue Fever in Urban Areas of Rawalpindi District in Pakistan During 2017: A Case Control Study (Preprint)
Authors: Awan Najma Javed , Chaudhry Ambreen , Hussain Zakir , Baig Zeeshan Iqbal , Baig Mirza Amir , Asghar Rana Jawad , Khader Yousef , Ikram Aamer
Published: January 2021

BACKGROUND

During August 2017, increased numbers of suspected dengue fever cases were reported in the hospitals of Rawalpindi district. A case control study was conducted to determine the risk factors among urban areas, dengue serotype, and recommend preventive measures.

OBJECTIVE

The objective of the investigation was to determine the risk factors among urban areas, dengue serotype, and recommend preventive measures.

METHODS

A case was defined as having acute febrile illness with one or more of the following symptoms: retro-orbital pain, headache, rash, myalgia, arthralgia, and hemorrhage. The cases were residents of Rawalpindi and were confirmed for dengue fever from August 30, 2017, to October 30, 2017. All NS1 confirmed cases from urban areas of Rawalpindi were recruited from tertiary care hospitals. Age- and sex-matched controls were selected from the same community with a 1:1 ratio. Frequency, univariate, and multivariate analyses were performed at 95% CI with P<.05 considered statistically significant.

RESULTS

Totally 373 cases were recruited. The mean age was 36 (SD 2.9) years (range 10-69 years), and 280 cases (75%) were male. The most affected age group was 21-30 years (n=151, attack rate [AR] 40%), followed by 31-40 years (n=66, AR 23%). Further, 2 deaths were reported (case fatality rate of 0.53%). The most frequent signs or symptoms were fever (n=373, 100%), myalgia and headache (n=320, 86%), and retro-orbital pain (n=272, 73%). Serotype identification was carried out in 322 cases, and DEN-2 was the dominant serotype (n=126, 34%). Contact with a confirmed dengue case (odds ratio [OR] 4.27; 95% CI 3.14-5.81; P<.001), stored water in open containers at home (OR 2.04; 95% CI 1.53-2.73; P<.001), and travel to a dengue outbreak area (OR 2.88; 95% CI 2.12-3.92; P<.001) were the main reasons for the outbreak, whereas use of mosquito repellents (OR 0.12; 95% CI 0.09-0.18; P<.001) and regular water supply at home (OR 0.03; 95% CI 0.02-0.04; P<.001) showed protective effects. The geographical distribution of cases was limited to densely populated areas and all the 5 randomly collected water samples tested positive for dengue larvae.

CONCLUSIONS

Stored water in containers inside houses and subsequent mosquito breeding were the most probable causes of this outbreak. Based on the study findings, undertaking activities to improve the use of mosquito repellents and removing sources of breeding (uncovered water stored indoors) are some recommendations for preventing dengue outbreaks.
Risk Factors of Extensively Drug Resistant Typhoid Fever Among Children in Karachi: Case-Control Study (Preprint)
Authors: Vighio Anum , Syed Muhammad Asif , Hussain Ishfaque , Zia Syed Masroor , Fatima Munaza , Masood Naveed , Chaudry Ambreen , Hussain Zakir , Iqbal Baig Mirza Zeeshan , Baig Mirza Amir , Ikram Aamer , S Khader Yousef
Published: January 2021

BACKGROUND

Extensively drug resistant typhoid fever (XDR-TF) has been responsible for an ongoing outbreak in Pakistan, which began in November 2016.

OBJECTIVE

This study aimed to determine the risk factors associated with XDR-TF.

METHODS

This age- and sex-matched case-control study was conducted during May-October 2018 in Karachi. All patients with XDR-TF were identified from the laboratory-based surveillance system data. Cases included patients aged <15 years living in Karachi with culture-positive Salmonella enterica serovar Typhi with resistance to chloramphenicol, ampicillin, trimethoprim/sulfamethoxazole, fluoroquinolones, and third-generation cephalosporins. Age- and sex-matched controls included children free from the symptoms of TF, aged under 15 years, and residing in Karachi. All controls were recruited from among those who attended outpatient clinics.

RESULTS

A total of 75 cases and 75 controls were included in this study. On univariate analysis, the odds of having XDR-TF were 13-fold higher among participants who used piped municipal water than among those who did not (odds ratio [OR] 12.6, 95% CI 4.1-38.6). The use of bore water was significantly associated with XDR-TF (OR 5.1, 95% CI 1.4-19.0). Cases were more likely to report eating French fries with sauce (OR 13.5, 95% CI 3.9-47.0) and poppadum (OR 3.4, 95% CI 1.7-6.7) from street vendors than controls. Boiling water at home was negatively associated with XDR-TF (OR 0.3, 95% CI 0.2-0.7). On multivariate analysis, 2 factors were independently associated with XDR-TF. Using piped municipal water (OR 10.3, 95% CI 3.4-30.4) and eating French fries with sauce from street vendors (OR 8.8, 95% CI 2.1-36.2) were significantly associated with an increased odds of XDR-TF.

CONCLUSIONS

Community water supply and street food eating habits were implicated in the spread of the superbug S typhi outbreak, which continues to grow in Karachi. Therefore, it is recommended to improve the community water supply to meet recommended standards and to develop a policy to improve the safety of street food. In addition, health authorities are required to conduct mass vaccination for TF among high-risk groups.
Eleutherine palmifolia (L.) Merr. Extract Increases The Crypts and Caspase-3 Expression in Colitis-Associated Colon Cancer Model
Authors: Mutiah Roihatul , Firsyaradha Wahyi Yucha , Sari Riza Ambar , Annisa Rahmi , Kristanti Risma Aprinda , Indrawijaya Yen Yen Ari , Griana Tias Pramesti , Listiyana Anik
Published: January 2021

It is known that Eleutherine palmifolia (L.) Merr contains flavonoid and polyphenol as bioactive compounds that have the ability as chemopreventive agents. This study aims to examine the effect of Eleutherine palmifolia (L.) Merr extract (EPE) on colon histopathology and the enhancement of caspase-3 expression in BALB/c mice of colitis-associated colon cancer (CAC) model. Thirty Balb/c female mice were used in this study and were divided into six groups. Five mice in one group were normal or negative control (given phosphate-buffered saline), and twenty-five mice were induced intraperitoneally with 10 mg/kg BW AOM (Azoxymethane), and it was followed by the administration of 5% DSS (Dextran Sodium Sulfate) every two weeks for 20 weeks. At the sixth week, one mice in each group was sacrificed for the Fecal Occult Bold Test (FOBT) and serum amyloid α (SAA) test to ensure that CAC was indeed formed. The administration of EPE with varying doses was started from the eighth week and was continued until the 21st week. The length of the colonic crypt was measured through histology appearance using Hematoxylin-eosin (HE) staining while the immunohistochemical method was used to observe apoptotic activity through the enhancement of caspase-3 expression. The results showed that the increase in EPE dosage also increased the crypt colon length compared to the positive control group. The administration of 1.00 mg/20gBW EPE significantly increased cell apoptosis which can be observed through caspase-3 expression compared to the positive control group (p<0.05). Based on these data, the extract of EPE can be developed as phytotherapy for chemopreventive.
Liquisolid Tablets Formulation of Atorvastatin Calcium Using Polyethylene Glycol 400 as Solvent and Some Carrier Materials
Authors: Windriyati Yulias Ninik , Badriyah Matsniyyatul , Kusumaningtyas Diar Arum , Riesmalia Rian Lesta
Published: January 2021

The dissolution of atorvastatin calcium need to be improved since included BCS Class II drugs with low solubility and high permeability, meaning that the dissolution affects the bioavailability of drugs. This research aimed to develop a formulation of a liquisolid tablet using PEG 400 as a solvent and some carrier materials in various compositions to increase the dissolution of atorvastatin calcium. Different formulations of liquisolid tablets were conducted using different quantities of carrier and coating material for adsorbing liquid solvent to produce a free-flowing and compressible powder. Avicel PH 101, Avicel PH 102, Neusilin US2 were employed as the carrier and Aerosil 200 as the coating material. A disintegrant and lubricant were then added to the formed liquisolid system and compressed into tablets by the direct compressing method. The liquisolid tablets were characterized for their tableting properties and possible drug-excipient interaction by XRD and FTIR analysis. The tableting characteristics of atorvastatin calcium liquisolid tablets were within the acceptable limits criteria. The dissolution of AA4 and NA1 liquisolid tablets was higher compared to marketed tablets. Based on the XRD and FTIR analysis, no interactions between drug and excipient.
Self Nano-Emulsifying Drug Delivery System (SNEDDS) of Curcuma Mangga Val. Essential Oil and The Stability Study
Authors: Sudibyo Retno Sunarminingsih , Mahdi Lukman , Martien Ronny
Published: January 2021

Essential oil of Curcuma mangga Val. has been reported to have cytotoxic effect against cancer cell lines. But this oil is unstable in dispensing so that a self nano-emulsifying drug delivery system (SNEDDS) of the oil was conducted to solve the problem and improve its potency. In the study, optimization, verification, characterization, and stability test of the SNEDDS formula were carried out respectively by simplex lattice design (SLD) on Design Expert ver. 10 software, droplet size and Zeta potential determinations using particle size analyzer (PSA) instrument, as well as heating-cooling and freeze-thaw methods.

The best SNEDDS formula resulted was Miglyol : Tween 80 : PEG 400 = 16.034% : 68.380% : 15.586%; with transmittance of 84.47 + 1.05%, droplet size of 15.75 nm, zeta potential of -8.54 mV, polydispersity index (PDI) of 0.188, emulsifying time of 49.67 + 1.7 seconds in distilled water, 24.33 + 4.19 seconds in artificial gastric fluid and 21.33 + 2.87 seconds in artificial intestine fluid. After a freeze-thaw test there was no change on the emulsion’s clarity, color, smell, as well as no separation, which means that the formula was stable thermodynamically.

The optimum SNEDDS formula resulted has small particle size, better emulsifying time in artificial gastric and intestine fluids, as well as better thermodynamic stability, which in turn will improve the cytotoxic activity of the Curcuma mangga Val. rhizome oil toward cancer cells.
Sex-dependent variations in anti-nociceptive and antipyretic effects of rhizome and stem extract of Schumannianthus dichotomus Roxb. in male and female mice
Authors: Basher Mohammad Anwarul , Hoque Md. Rafiul , Roy Roni , Hosen Sazzad , Karim Irin , Bhowmik Tanaya , Akter Afroza
Published: January 2021

Schumannianthus dichotomus (Roxb.) is a perennial shrub from Marantaceace family. In traditional medicine, rhizome of the plant is used in fever and stem is used in earache. We aimed to substantiate these therapeutic claims by examining their effects in mice model. Antinociceptive effect was evaluated by three pain models and antipyretic effect was tested by yeast induced hyperthermia experiment. Influence of mice sexes on these pharmacological effects was examined by performing experiments separately on male and female mice. Quantitative analyses of total phenols and flavonoids were performed. Antinociceptive effects showed striking sex dimorphism. In hind paw licking test, male mice showed significant reductions in licking in both phases for both rhizome and stem extracts while significant effect was observed only in late phase in female mice. In writhing test, antinociception is more profound in male than in female. In hot plate test, stem was more effective than rhizome in male mice while female mice produced little effect for both extracts. Antipyretic experiment also showed varied effect in male and female mice; both extracts showed significant decrease in body temperatures. Rhizome showed greater effect in female mice while stem was more effective in male mice. Total phenol and flavonoid in rhizome were found 103.08 mg GAE (gallic acid equivalent) and 9.07mg QE (quercetin equivalent) respectively while in stem, these were 43.39mg GAE and 20.93 QE. Antinociceptive and antipyretic effects of rhizome and stem extracts endorsed the traditional uses of S. dichotomus. Also, differential effects based on mouse sex indicate the prerequisite of both male and female mice model in therapeutic evaluations of plant extract.
Effects of Health Informations System “Dosing Gama” on Time Efficiency in Dosage Adjustment Evaluation
Authors: Hajma Lilla Prapdhani Agni , Wahyono Djoko , Rahmawati Fita
Published: January 2021

Indonesian Ministry of Health shows an increase in patients with impaired kidney and liver function by 10-50% since 2007. The increase is a challenge for pharmacists in conducting pharmaceutical care, which is that dose adjustment for these patients takes a long time. Dosing GAMA, an application that has been developed in 2018, is expected to overcome these obstacles. This study aims to identify the use of the Dosing GAMA application to assist pharmacists in making dose adjustments evaluation more efficient and to assess pharmacist's acceptance of the application. This study was a quasi-experimental study using post-test with control group design. Respondents were recruited by selecting pharmacists according to the inclusion criterion. The control group consisted of 26 pharmacists who made dose adjustments manually, and the intervention group consisted of 26 pharmacists who made dose adjustments using the Dosing GAMA application. Data were obtained by measuring the time required by the pharmacist to make dose adjustments. The intervention group was then asked to complete a perceived acceptance questionnaire. The study indicated that Dosing GAMA could reduce the time needed for dose adjustment evaluation (p<0.05). An average time spent by pharmacists with Dosing GAMA was shorter than that spent by those who made dose adjustments manually without application (13.81±0.78 min vs. 27.5±1.23 min). Overall, the pharmacists have high perceived acceptance of the application. The study results can be used as the basis for developing the application. Furthermore, it is expected that the Dosing GAMA can improve pharmacists’ performance in providing effective pharmaceutical care.
Building Land Cover Objects Following the IPCC Guidelines for Carbon Emission Estimation. Case Study in the Central Highlands of Vietnam
Authors: Hung Le Q. , Thao Vu T. P.
Published: January 2021

We estimated the carbon emissions in the field of Land Use, Land Use Change, and Forestry (LULUCF) by using advanced technology to build the input data. Remote sensing, including satellite remote sensing and Unmanned Aerial Vehicles (UAV) with transparency, multi-time, and wide coverage characteristics, is useful in this area. The article focuses on the proposed regulations and building process of subjects in the land cover of the Vietnamese mainland following the guidance of the Intergovernmental Panel on Climate Change as applied to carbon emission estimation. We propose a process to estimate carbon emissions using the Agriculture and Land Use Greenhouse Gas Inventory software with input data extracted from the remote sensing images. An experiment on land cover change was carried out over ten years between 2006 and 2016 in the Central Highlands of Vietnam. The results obtained with remote sensing data classification for land cover categories achieved a reliability of 69% for the year 2006 and 66% for the year 2016. The carbon emission estimation data were checked and used in Vietnam’s biennial update report to the United Nations Framework Convention on Climate Change, including content and updated information on the greenhouse gas inventory.
Modyfikowanie parametrów detonacyjnych indywidualnych materiałów wybuchowych
Authors: Maranda Andrzej , Górniewicz Dominika , Paszula Józef , Jóźwik Paweł
Published: January 2021

Individual explosives such as hexogen, octogen or TNT can be characterized by determining their thermochemical and detonation parameters. Some of these parameters can be modified by changing the diameter of the charge, type of confined or density. However, a much greater possibility of their change can be obtained by forming mixtures with various additives.
The paper presents the results review of literature data regarding the impact of various additives on the detonation and thermochemical parameters of individual explosives and of research on selected detonation parameters of hexogen and octogen compositions with glass microspheres and microballoons made of plastic. Measured parameters were: critical diameter and layer as well as detonation velocity. An increase in the critical diameter and layer was observed as well as a decrease in the detonation velocity along with th increase in the content of the inertial component in the explosive mixture.
Technological applications of border effects by hole charges system explosion
Authors: Kravets Viktor , Shukurov Azar , Zakusylo Roman , Kovtun Andrij
Published: January 2021

The technique of blasting in a mining is based mainly on application of the systems of the prolonged charges, which provide the rational distributing of charges explosive in the destroyed volume of rock mass. Large majority of output volumes is provided by the opencut method which fully is practically based on application of the downhole charges systems. A downhole charge must execute a few functions. Main of them is destruction of rocks around the mining hole, bit also avoiding the problem of overdrill in mass explosions is very important. Reduction or complete liquidation of overdrill is possible by introduction of structural decisions, which create the reorientation of power stream of explosion in direction which coincides with the plane bench toe. Additional structural decisions for a control of overdrill size, capable to orient development of deformation process from the axis of downhole charge along the project bench toe, are needed. The article discusses the development of the deformation zone during the explosion, which allows to solve the problem of over-drilling.
Investigation of properties of Cu-Al explosively welded bimetals
Authors: Lokaj Ján , Sahul Miroslav , Sahul Martin , Nesvadba Petr
Published: January 2021

Explosion welding of cooper C10200 to AW 5083 aluminium alloy was performed. The C10200 was proposed as a flyer plate. A parallel setup was used during explosive welding. Bimetals were characterized by regular wavy interface. The intermetallic compound (IMC) layer was observed at the interface of bimetals after 12 month, however, no annealing was performed. EDX analyses revealed that the interface layer consists of the intermetallic compound CuAl. Microhardness at the interface increased due to the presence of the IMC and work hardening as well.
Управление стоимостью инвестиционно-строительных проектов
Authors: Мишланова М.Ю.
Published: January 2021

Представлены теоретические основы развития стоимости инвестиционно-строительных проектов. Разработан тектологический подход к моделированию инвестиционно-строительной деятельности, что позволило систематизировать дефиниционную базу и идентифицировать микросистему инвестиционно-строительного проекта. Рассмотрено формирование стоимости инвестиционно-строительных проектов по блокам планирования, бюджетирования и создания. Представлены методологические основы процессов управления стоимостью инвестиционно-строительных проектов: методы оценки стоимости и управление изменениями в проекте. Рассмотрена подсистема поддержки принятия управленческих решений— контроллинг инвестиционно-строительных проектов. Разработаны основные положения адаптивного управления инвестиционно-строительными проектами на основе продукционной модели с разработкой базы прецедентов. Представлено обеспечение управления проектами в виде управленческого учета, регламентации контроллинга и программного обеспечения.Для аспирантов строительных вузов, преподавателей, научных работников и специалистов.
Comparative Evaluation of Outcomes After Standard versus “Modified Large PCNL”- Is Larger Better…?
Authors: Jain Deep Kumar , Hegde Padmaraj , Chawla Arun
Published: January 2021

Objectives

To comparatively evaluate the outcomes of standard percutaneous nephrolithotomy (PCNL) versus a 36 Fr PCNL in terms of operative time, complications, hospital stay, and stone free rates.

Patients and Methods

The data of 125 PCNL cases, out of the 168 PCNLs done from January 2014 to December 2015, was retrospectively analyzed within two subsets, namely group-A (standard PCNL with 22-32 Fr Amplatz) and group-B (modified large PCNL with 36 Fr Amplatz). The demographic profile, stone characteristics, operative and laboratory parameters, and stone clearance rate were analyzed to determine the safety and efficacy of the modified large PCNL as against standard PCNL.

Results

Group-A comprised 88 patients with 100 renal units, while group-B comprised 37 patients with 45 renal units. The mean age of the patients in Group-A was 49.1 + 13.1 years, and in Group-B was 52.4 + 11.4 years (range 25-84 years) with a male to female ratio of 4:1. 54.5% and 75.7% unilaterally intervened, group-A and group-B patients respectively, required < 90 minutes for the procedure. Nine patients (10.2%) each of unilaterally and bilaterally intervened group-A cases had an operative time that exceeded 120 minutes compared to only two (5.4%) bilaterally intervened group-B cases. For patients with stone burden >1000 mm2, there was statistically significant (p = < 0.0001) higher complete stone clearance rates with the 36Fr PCNL compared to standard PCNL.

Conclusion

Our retrospective analysis revealed that 36 Fr PCNL is safe and efficacious in carefully selected patients with large stone burdens providing the advantage of better stone-free rates, less operative time, lesser need for additional punctures without increasing blood transfusion and complications rates. However, more extensive prospective randomized trials are needed to confirm this perceived benefit.
Assessment and forecast of dangerous exogenous processes activation during climate change based on the analysis of thematic maps data
Authors: Morozova A.V. , Lihacheva E.A. , Chesnokova I.V. , Koshkarev A.V.
Published: January 2021

The research purpose is to develop the principles of cartographic assessment and long-term risk forecasts for the development of cryogenic and erosion processes in the continental zone of the Russian Arctic sector under global climatic changes. ′Map of the modern dynamics of Northern Eurasia (within Russia and neighboring countries) 1
Co-creating Service-Dominant Business Artifacts with Action Design Research
Authors: Lüftenegger Egon
Published: January 2021

Our project started as an innovation initiative for shaping the future of an international Dutch conglomerate in the financial services industry. This endeavor took the shape of a collaboration between academics and practitioners that evolved from unique goals for industry as fast results and real scientific results towards a collaborative approach. We formalized this collaboration by using action design research (ADR) for achieving impact within the company while generating new knowledge. The use of ADR resulted in the co-creation of artifacts that brought mutual benefits, resulting in a win-win situation for the academia and industry. On the one hand, academics were able to develop a framework and its underlying artifacts for service-dominant business design and engineering. On the other hand, the framework helped to achieve organizational change for shifting from an asset-dominant business towards a service-dominant one.
TEXTO DAS PALAVRAS E TEXTO DOS CORPOS (PEÇASAMBA)
Authors: Barbosa Neto Esperidião Barbosa
Published: January 2021

A psicologia, pela via da psicanálise, sugere um diálogo com a arte da dança. Pensamos o corpo como instância psíquica, palco do movimento cuja expressão se faz palavra. Nesse cenário o sentido se produz e pode ser ressignificado; dançantes se transformam no enredo de como a vida é. Nosso objetivo é apresentar uma peça teórica (e descrição de uma prática) articulando o corpo à dança, cuja arte é capaz de ressignificação da experiência traumática. O trabalho se compõe de duas partes, o texto das palavras e o texto dos corpos. No primeiro uma peça teórica sobre o corpo e a dança, no outro a prática dançante e o diálogo corporal. Conclui-se que a dança, como arte e objeto de transformação, pode resgatar o sentido perdido pelo sujeito no âmbito individual, coletivo, histórico e sociocultural. O texto, seja ele das palavras ou dos corpos, é efeito do tecimento de algum sentido.Palavras-chave:  corpo psíquico; dança; samba de gafieira, sentido.
O ato de narrar e a produção de conhecimento em Psicologia Social
Authors: Battistelli Bruna Moraes , Franceschini Erica , Luciana Magalhães Novais Flávia , Guimarães Willian
Published: January 2021

Este artigo tem como objetivo discutir possibilidades teóricas no que tange às narrativas de mulheres, dando a ver um ensaio composto por plurais vozes. Partimos do campo da Psicologia Social, a fim de pluralizar suas referências diante daquilo que incide do/no tempo presente e que permeia as discussões pertinentes aos estudos de gênero. Para tanto, buscamos dialogar com autores e autoras que não costumam frequentar as páginas de textos desta área, tais como Conceição Evaristo. Nossa aposta metodológica pauta-se na ideia de narrar enquanto meio de produção de histórias de mulheres que, por sua vez, produzem conhecimento; elegemos um viés interseccional, numa discussão que leve em conta marcadores de raça, gênero e classe social. Deste modo, pactuamos com a ideia de que a produção de conhecimento em Psicologia possa se dar pela produção de novas narrativas, nas quais estas mulheres sejam reconhecidas como protagonistas e porta-vozes de suas próprias histórias.
Agenda 2030
Authors: Lima-Rodrigues Luzia Mara Silva , Rodrigues David António
Published: January 2021

A Educação Inclusiva permanece um grande desafio para todos os sistemas educativos.  Consagrada com um dos Objetivos do Milénio, a Inclusão enfrenta dificuldades de se afirmar em sistemas educativos que não foram concebidos para lidar com todo o universo de alunos e alunas.  Este ensaio apresenta o conceito de Inclusão e discute este conceito na sua relação com os valores e práticas da Educação Física.  São igualmente discutidos cinco desafios que assumem maior relevância quando se trata de criar efetivos ambientes inclusivos na área das atividades motoras: as atividades, as metodologias, a avaliação, a cooperação e formação dos professores e ainda a criação de ambientes inclusivos.
Educação e política
Authors: Rocha Junior João Mendes da , Dalarosa Adair Ângelo
Published: January 2021

Uma das discussões de maior visibilidade no momento atual na educação brasileira é a proposta de separação, ou defesa da “neutralidade” na relação entre educação e política, levada adiante pelo movimento Escola Sem Partido. Esse artigo se insere nessa discussão com o objetivo principal de problematizar as contradições inerentes a esse debate. Para tanto, utilizamos como metodologia de análise os princípios do materialismo histórico dialético, que nos permitirá explicitar que educação e política como entes separados mostra-se como algo impossível. A educação escolar é política em sua essência, ao ser o espaço de introjeção de normas, conhecimentos e, no modo de produção vigente, é um espaço de lutas. Com isso, vemos que a defesa de uma escola “apolítica” é de interesse de uma política que busca a domesticação de um povo, que, mais do que conseguir criar uma lei específica sobre esse tema, busca inibir qualquer foco de resistência que possa surgir num espaço como a escola.
Interações na rede de Políticas na Educação Infantil no Brasil e a produção do texto legal (2001-2015)
Authors: Bortot Camila Maria , Lara Ângela Mara de Barros
Published: January 2021

O artigo apresenta uma problematização e análise sobre a elaboração em rede de documentos de políticas para a Educação Infantil no Brasil entre 2001e 2015, com revisão bibliográfica e análise documental. No estudo identificamos um espaço de abertura que se caracteriza como colaboração à concertação social, com multiplicidade de instituições de coletivos que acentua uma maior predominância de setores privados ao final do período analisado. Concluímos que houve uma democratização na elaboração de documentos para a área, uma vez propicia a direta correlação de forças dos interesses coletivos que integram as discussões, contudo, indicam um acolhimento a interesses da classe hegemônica burguesa pelas instituições privadas e de uma pauta internacional. Ainda, apreendemos que as diferentes colaborações por meio de redes os atores não estatais cooperam entre si e estabelecem interdependências, influenciando, assim, no processo e no conteúdo da política.
O discurso sobre as metodologias ativas para o ensino de biologia
Authors: Palcha Leandro Siqueira
Published: January 2021

Há muitas e boas razões para incluir as metodologias ativas de aprendizagem na formação de professores, já que elas permitem tanto ao docente quanto ao discente conscientizarem de seu papel ativo, participativo e crítico à altura do tempo em que vivemos. Neste artigo, relatam-se os resultados de uma pesquisa de natureza qualitativa, realizada com o objetivo de analisar o discurso dos licenciandos em sobre o uso de metodologias ativas para o ensino de biologia. O corpus de análise é composto pelos dizeres de doze licenciandos e discutido pelo referencial da Análise de Discurso Francesa. Os resultados destacam três abordagens, denominadas por trilhas, que expressam os sentidos produzidos pelos licenciandos sobre a aprendizagem ativa. Por fim, estes sentidos sinalizam uma forma de problematizar o discurso pedagógico autoritário e desbravar as trilhas inovadoras e desejáveis para a docência.
PHYSICAL, CHEMICAL, AND SENSORY CHARACTERISTICS OF INSTANT NOODLES WITH PURPLE SWEET POTATO FLOUR (IPOMOEA BATATAS L. POIR) SUBSTITUTION AT VARIOUS CONCENTRATIONS
Authors: Rahim Abdul , Rostiati Rostiati , Pratiwi Pratiwi
Published: January 2021

Sweet potatoes in general, including vines that have tubers as a producer of carbohydrates, but the quantity and quality is very different from other tubers. Instant noodles are generally made from raw materials of wheat flour, but with the abundance of sweet potatoes found, noodles are made using purple sweet potato flour instead of wheat flour. The purpose of this study was to determine the effect of purple sweet potato flour substitution at various concentrations on the physical, chemical and sensory tests of instant noodles. The study was conducted at the Agroindustry Laboratory, Faculty of Agriculture, University of Tadulako, from June to December 2019. The experiment was arranged using a Completely Randomized Design (CRD) with 1 factor, namely the substitution of instant noodles purple sweet potato flour at a concentration of 0.5,10,15, 20.25 and 30%. The treatment was repeated 3 times so that 21 units of the experiment were obtained. For sensory testing using a Randomized Block Design (RBD) with a panelist of 30 people. Observation parameters consisted loss of solids due to cooking (KPAP), water absorption, water content, ash content and sensory tests. The results of the study of purple sweet potato flour substitution at various concentrations gave the best effect on the concentration of 30% on instant noodles produced based on physical, chemical and sensory properties. With the highest loss of solids due to cooking ( KPAP). The absorption of instant noodles decreases with increasing concentration of purple sweet potato flour. Instant noodle water content tends to be constant in every treatment. Ashes of instant noodles increase with increasing concentration of purple sweet potato flour and the sensory properties of color, texture, aroma, and taste of instant noodles produced increase with increasing concentration of purple sweet potato flour with hedonic scale categories like. Noodles substituted with purple sweet potato flour can be consumed as instant noodles such as those circulating in the market.
Prior use of therapeutic anticoagulation does not protect against COVID-19 related clinical outcomes in hospitalized patients: a propensity score-matched cohort study
Authors: Spiegelenberg Janneke , Gelder Marleen van , Maas Martje , Hovens marcel , Esselink Anne , Dofferhoff Anton , Janssen Rob , Maat Josephine van de , Hoogerwerf Jacobien , Janssen Nico , Apeldoorn Marianne van , Kerckhoffs Angèle , Veerman Karin , Blaauw Marc , Hassing Robert Jan , Kramers Kees , Leentjens Jenneke
Published: January 2021

The hypercoagulable state observed in COVID-19 could be responsible for
morbidity and mortality. In this retrospective study we investigated
whether therapeutic anticoagulation prior to infection has a beneficial
effect in hospitalized COVID-19 patients. 1154 COVID-19 patients
admitted to 6 hospitals in the Netherlands between March and May 2020
were included. We applied 1:3 propensity score matching to evaluate the
association between prior therapeutic anticoagulation use and clinical
outcome, with in hospital mortality as primary endpoint. 190 (16%)
patients used therapeutic anticoagulation prior to admission. In the
propensity score matched analyses, we observed no associations between
prior use of therapeutic anticoagulation and overall mortality (RR 1.02
(95% CI; 0.80-1.30) or length of hospital stay (7.0 [4-12] vs 7.0
{4-12] days, p=0.69), although we observed a lower risk of pulmonary
embolism (RR 0.19 (95% CI; 0.05-0.80). This study shows that prior use
of therapeutic anticoagulation is not associated with improved clinical
outcome in hospitalized COVID-19 patients.
The magazine “Slavenska muzika” (1939–1941) in the history of Serbian music periodicals
Authors: Vasic Aleksandar
Published: January 2021

From November 1939 to March 1941, the monthly magazine ?Slavenska muzika?, a
journal of the Association of Friends of Slavic Music, was published in
Belgrade. The magazine did not differ from other Serbian magazines of the
interwar period in its sections. ?Slavic music? also published essays on
music, music criticism, reviews of books and music editions, notes, news,
obituaries, and in one case, polemics. However, differentia specifica of
this review is the exclusive focus on the music of the Slavic nations. The
study provides a review and analysis of the texts in this journal. It was
noticed that in ?Slavic music? were crossed the Slavophile idea, which has a
long tradition among Serbs, and Marxism, at that time strongly represented
by one part of Belgrade musicians. The study also contains an integral
bibliography of ?Slavic music?, which has not been published so far.
Dynamic uni- and multicellular patterns encode biphasic activity in pancreatic islets
Authors: Jaffredo Manon , Bertin Eléonore , Pirog Antoine , Puginier Emilie , Gaitan Julien , Oucherif Sandra , Lebreton Fanny , Bosco Domenico , Catargi Bogdan , Cattaert Daniel , Renaud Sylvie , Lang Jochen , Raoux Matthieu
Published: January 2021

Biphasic secretion is an autonomous feature of many endocrine micro-organs to fulfill physiological demands. The biphasic activity of islet β-cells maintains glucose homeostasis and is altered in type-2 diabetes. Nevertheless, underlying cellular or multicellular functional organizations are only partially understood. High-resolution non-invasive multi-electrode array recordings permit simultaneous analysis of recruitment, of single-cell and of coupling activity within entire islets in long-time experiments. Using this approach, we addressed the organizational modes of both, 1st and 2nd phase, in mouse and human islets under physiological and pathophysiological conditions. Our data provide a new uni- and multicellular model of islet b-cell activation: during the 1st phase, small but highly active β-cell clusters are dominant, whereas during the 2nd phase electrical coupling generates large functional clusters via multicellular slow potentials to favor an economic sustained activity. Post-prandial levels of glucagon-like peptide-1 (GLP-1) favor coupling only in the 2nd phase, whereas aging and glucotoxicity alter coupled activity in both phases. In summary, biphasic activity is encoded upstream of vesicle pools at the micro-organ level by multicellular electrical signals and their dynamic synchronization between β-cells. The profound alteration of the electrical organization of islets in pathophysiological conditions may contribute to functional deficits in type-2 diabetes.
Vi var folket. Møde med østeuropæerne 30 år efter Murens fald
Authors: Skak Mette
Published: January 2021

Abstract: We Were the People. Meetings with Eastern Europeans 30 Years After the Fall of the Berlin WallMette Skak (Aarhus University) reviews Vi var folket. Møde med østeuropæerne 30 år efter Murens fald (We Were the People. Meetings with Eastern Europeans 30 Years After the Fall of the Berlin Wall) written by Thomas Ubbesen and Anne Haubek.
Women Empowerment: Current Insights and Debates
Authors: PARIHAR SEEMA MEHRA , BANNERJEE TAPATI
Published: January 2021

Women empowerment even today is as important as it was ever before. This paper delves into a few current debates and an approach, highlighting that engagement with actions required towards women empowerment is necessary and relevant. Meeting with women empowerment demands a sensitive driver who understands its relevance and is ready to pull and push measures with passion. The paper highlights that if we focus on the idea of women empowerment, we must ask ourselves what it means in terms of a socio-economic, socio-political, or, put, the social reality of gender parity in our societies and around the world as well. Empowerment for a person would, at a basic level, mean the person's fundamental ability to have power or control of their own lives concerning the fundamental rights and freedom that every person is entitled to. So, in a broad sense, women empowerment would mean helping empower women to be independent and have more control over their own lives. This paper is based on observations, literature review, and multiple interactions, including data collected through structured and unstructured questionnaire surveys. Writing this paper was to understand the social space that women occupy before delineating the framework for ' Women Empowerment Atlas Project'** and suggest ways to uplift their status in society. Science and technology as mediums can help raise awareness among women and aid them in myriad ways and empower them with multiple livelihood opportunities, besides exhibiting the possibility of women safe gadgets which, thereby evolving safe spaces and ecosystem.
AKTIVITAS INSEKTISIDA EKSTRAK DAUN DAN BIJI TEPHROSIA VOGELII J. D. HOOKER (LEGUMINOSAE) DAN EKSTRAK BUAH PIPER CUBEBA L. (PIPERACEAE) TERHADAP LARVA CROCIDOLOMIA PAVONANA (F.) (LEPIDOPTERA: CRAMBIDAE)
Authors: Abizar Muhamad , Prijono Djoko
Published: January 2021

Insecticidal activity of leaf and seed extracts of Tephrosia vogelii J. D. Hooker (Leguminosae) and fruit extract of Piper cubeba L. (Piperaceae) on the cabbage head caterpillar, Crocidolomia pavonana (L.) (Lepidoptera: Crambidae).  Ethyl acetate leaf and seed extracts of Tephrosia vogelii and a solid fraction of ethyl acetate fruit extract of Piper cubeba were evaluated for their insecticidal activity on second-instar larvae Crocidolomia pavonana by a leaf-residue feeding method in the laboratory.  Leaf extracts of purple and white-flowered T. vogelii showed the same pattern of component separation on silica gel TLC plate (Rf between 0.21 and 0.94), and likewise the separation of components of seed extracts of purple and white-flowered T. vogelii (Rf between 0.31 and 0.96).  All four kinds of T. vogelii extracts showed intense UV-absorbing nonpolar spots (Rf > 0.8).  Based on LC50 ratio at day 4, leaf extract of purple-flowered T. vogelii (LC50 0.075%) was 4.30, 2.70, 2.21, and 1.64 times more toxic than fruit extract of P. cubeba, seed extract of white-flowered T. vogelii, seed extract of purple-flowered T. vogelii, and leaf extract of white-flowered T. vogelii, respectively.  All T. vogelii extracts were more toxic to C. pavonana larvae than P. cubeba fruit extract.  At LC95 level, a mixture of leaf extract of purple-flowered T. vogelii and fruit extract of P. cubeba (5:9, w/w) was more toxic to C. pavonana larvae than each extract tested separately.  This extract mixture had synergistic joint action against C. pavonana larvae both at LC50 and LC95 level.  Thus, leaf extract of purple-flowered T. vogelii and its mixture with P. cubeba fruit extract are promising to be used for controlling C. pavonana.
ELIMINATION OF Cucumber Mozaic Virus (CMV) FROM A RANGE OF CHRYSANTHEMUM CULTIVARS THROUGH MERISTEM CULTURE FOLLOWING HEAT TREATMENT
Authors: Budiarto Kurniawan
Published: January 2021

Cucumber Mosaic Virus (CMV) is one of pathogenic viruses that commonly found and has caused significant losses in many chrysanthemum growers in Indonesia.  Efforts have been made to get healthy plant source through eliminating virus from infected plants and one of the promising methods was the combination of thermotherapy and meristem culture. The research was conducted to find out the effect of meristem culture following heat treatments on the existence of CMV in infected chrysanthemum plantlets. The experiment was carried out in the laboratory of tissue culture and virology at The Indonesian Ornamental Crops Research Institute (IOCRI) from August 2007 until June 2008. A complete factorial with ten replications was designed to accomplish the combination of two factors.  The first factor was three chrysanthemum cultivars, namely Stroika, Dewi Sartika and White Fiji, while the second dealt with the durations of heat treatment i.e. one, two and three weeks.  The results showed that plantlet survival decreased, yet improved plantlet performance by faster bud initiation with lengthened heat duration.  The percentage of virus-free planlets also increased along with the duration of treatment and three weeks heat treatment followed by meristem culture effectively eliminated CMV from infected planlets.
HUBUNGAN ANTARA CURAH HUJAN DAN LUAS SERANGAN BELALANG KEMBARA (Locusta migratoria manilensis Meyen) DI PROVINSI LAMPUNG
Authors: Sudarsono Hamim , Hasibuan Rosma , Swibawa I Gede
Published: January 2021

Population outbreak of the oriental migratory locust, Locusta migratoria manilensis Meyen (Orthoptera: Aciridae), in Lampung between 1990’s to 2000’s has caused serious economic loss to agriculture.  Anticipation of the pest outbreak is required to prevent serious loss in the future; one of possible approach is by analyzing data of rainfall and locust damage area. The study was aimed to analyze the relationship between rainfalls and area of damage caused by locust population in rice and corn fields using 17 years period of data from Lampung Province.  The results indicate that locust damage occurred when there were high rainfalls followed low ones at wet season. Time lag of 8 month was determined as the period needed for L. migratoria manilensis to raise its population when the pest has developed gregarious colonies in the region.  Rainfalls between 248,27 mm/month (on corn fields) to 287,06 mm/month (on rice fields) were optimum for the initiation of the locust population increase after a period of dry weather in the region.  Results of autocorrelation tests indicate that the occurrence of locust damage in an area would be followed by population increase in a region where gregarious colonies have developed.