bluuebunny/crossref_metadata_2025 huggingface dataset:
Quality Learning Experiences, Self-Determination, and Academic Success
Authors: Solberg V. Scott , Howard Kimberly , Gresham Stephen , Carter Erik
Published: September 2013

Although fostering self-determination has emerged as a central element of recommended and evidence-based transition practices for adolescents with disabilities, few studies have examined the paths through which students develop the skills and dispositions that can enhance their self-determination and successful transitions. The authors used path analyses to examine the ways in which exposure to quality secondary learning environments contributed to the development of self-efficacy, motivation, and academic achievement among 135 high school students receiving special education services. Students with disabilities who reported having greater involvement in learning environments reflecting recommended transition practices (i.e., high-quality learning environments) demonstrated increased career-search self-efficacy. Students with greater career-search self-efficacy were more highly engaged in goal setting, which further predicted their motivation to attend school and academic self-efficacy. Finally, students with higher academic self-efficacy were found to have higher grades. The authors offer recommendations for enhancing the self-determination skills and opportunities of youth with disabilities by strengthening the quality and impact of transition education.
Black Supporters of the No-Discrimination Thesis in Criminal Justice
Authors: Gabbidon Shaun L. , Jordan Kareem L. , Penn Everette B. , Higgins George E.
Published: September 2013

This study examined a national sample of more than 600 Black Americans and their views on bias in the American criminal justice system. The research found that 26% of the Black respondents did not believe there was bias in the American criminal justice system. To explore the segment of respondents holding these views, we separated the sample into Blacks who believe there is bias in the system (referred to as the discrimination thesis or DT supporters) and those who opposed this belief (referred to as the no-discrimination thesis or NDT supporters). The NDT supporters were more likely to be younger, male, less educated, and have lower income than those respondents who supported the DT. NDT supporters were also more likely to believe that Blacks and Whites had equal job opportunities, have more confidence in the police, and believe that racism was not widespread.
The Extreme Right’s Relationship with Islam and Islamism in East-Central Europe
Authors: Mareš Miroslav
Published: September 2013

This article analyses the attitudes of extreme right actors from countries of East-Central Europe towards Islam and Islamism. First the broad spectrum of these attitudes is described, using the historical legacy and an analysis of situation in Western countries as the points of departure. This is followed by a description and analysis of extreme right entities and currents in East-Central Europe which cooperate with Islamists or view Islam in a favourable light. The next section examines the attitude of the extreme right towards Baathism and Arab nationalism. The penultimate section describes actors who established their profile on anti-Islamist issues, and the conclusion provides an overall summary of the present situation as well as estimated perspectives of future development.
Becoming a “Trusted Outsider”
Authors: Bucerius Sandra Meike
Published: September 2013

It is commonly assumed that successful ethnographers strive for insider status and avoid being regarded as an outsider. Very often and especially within criminology, an ethnographer’s ability to gain the trust of research participants is linked to his or her degree of similarity to them, particularly with respect to gender. By describing the research dynamics between an all-male group of second-generation immigrants in Frankfurt/Germany, the “gatekeepers” and myself—a female researcher of different socioeconomic and ethnic background—I suggest that being an outsider in general and a female in particular is not a liability one necessarily needs to overcome. I propose that achieving status as an outsider trusted with “inside knowledge” may provide the ethnographer with a different perspective and different data than that potentially afforded by insider status.
Claiming the past: Venezuelan historical films and public politics
Authors: Alvaray Luisela
Published: September 2013

Since 2000, multiple historical films and documentaries have been released that reference different stages of Venezuelan history. This trend reflects a society persistently exploring its past, mirrored in part by the policies of the Venezuelan government toward its cultural institutions. By analyzing historical films Taita Boves (2010) and Zamora (2009), this article explores some of the ideological currents that traverse Venezuelan society, raising questions about the role of film in social and political life. Ultimately, this essay contributes to the debate around the constitution of a national historical consciousness.
A redundant epistatic interaction between IRF5 and STAT4 of the type I interferon pathway in susceptibility to lupus and rheumatoid arthritis
Authors: Kim K , Cho S-K , Han T-U , Kim J-H , Kang S-J , Kang C , Bae S-C
Published: September 2013

Objective

K. K. and S.-K. C. are co-first authors, and C. K. and S.-C. B. are co-senior authors. Two transcription factors in the type I interferon pathway, IRF5 and STAT4, have been genetically associated with susceptibility to both systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). This study aimed to determine whether these two genes interact with each other to affect the disease susceptibilities.

Methods

The genetic interactions between IRF5 and STAT4 polymorphisms in SLE and RA susceptibility were examined using the epistasis options in PLINK software. This study analyzes the genetic data from 2558 unrelated Korean participants including 589 SLE patients, 987 RA patients, and 982 controls.

Results

All 12 polymorphisms were individually associated with SLE susceptibility ( p = 2.49 × 10−8 to 0.00360). Among the three SLE-associated polymorphisms of IRF5, rs77571059, alternatively called CGGGG(3–4) indel, exhibited the lowest p value (4.60 × 10−5) and accounted for the observed associations of the other two single-nucleotide polymorphisms (SNPs). Among the nine SLE-associated SNPs of STAT4, rs16833215 exhibited the lowest p value (2.49 × 10−8) and accounted for all the other associations. These two polymorphisms, rs77571059 of IRF5 and rs16833215 of STAT4, interacted with each other for SLE susceptibility in a redundant manner (ORinteraction = 0.77, Pepistasis = 0.040). Furthermore, these two polymorphisms, which had been individually associated with RA susceptibility, also interacted for RA susceptibility in the same manner (ORinteraction = 0.75, Pepistasis = 0.014).

Conclusions

A redundant interaction between IRF5 and STAT4 polymorphisms was found in susceptibility to the type I interferon pathway-associated rheumatic autoimmune diseases, SLE and RA, calling for further studies on confirmation of these findings.
Harvesting energy from vibrations of the underlying structure
Authors: Han Bo , Vassilaras Spyridon , Papadias Constantinos B , Soman Rohan , Kyriakides Marios A , Onoufriou Toula , Nielsen Rasmus H , Prasad Ramjee
Published: September 2013

The use of wireless sensors for structural health monitoring offers several advantages such as small size, easy installation and minimal intervention on existing structures. However the most significant concern about such wireless sensors is the lifetime of the system, which depends heavily on the type of power supply. No matter how energy efficient the operation of a battery operated sensor is, the energy of the battery will be exhausted at some point. In order to achieve a virtually unlimited lifetime, the sensor node should be able to recharge its battery in an easy way. Energy harvesting emerges as a technique that can harvest energy from the surrounding environment. Among all possible energy harvesting solutions, kinetic energy harvesting seems to be the most convenient, especially for sensors placed on structures that experience regular vibrations. Such micro-vibrations can be harmful to the long-term structural health of a building or bridge, but at the same time they can be exploited as a power source to power the wireless sensors that are monitoring this structural health. This paper presents a new energy harvesting method based on a vibration driven electromagnetic harvester. By using an improved Maximum Power Point Tracking technique on the conversion circuit, the proposed method is shown to maximize the conversion coefficient from kinetic energy to applicable electrical energy.
Multi-fault diagnosis of rotor system based on differential-based empirical mode decomposition
Authors: Ming Li , Fucai Li , Beibei Jing , Huiyu Bai , Hongguang Li , Guang Meng
Published: September 2013

Multi-fault diagnosis of rotor systems is a topical issue in the research of rotor dynamics. Empirical mode decomposition (EMD) has been introduced in fault diagnosis of rotor systems, which has proved to be usable and efficient in single fault diagnosis of a rotor system. However, in multi-fault diagnosis of a rotor system, because of the existence of a high-frequency fault signal, EMD is not as powerful as the diagnosis of a single fault in dealing with the decomposition of multi-faults. In this paper, differential-based empirical mode decomposition (DEMD) is introduced into multi-fault diagnosis of a rotor system. The analysis consequences show that the combination of any two faults among crack, rub-impact and pedestal looseness in multi-fault diagnosis can be decomposed successfully and efficiently under the application of the DEMD method, which is also more accurate and precise than the traditional EMD method.
Crack propagation and fracture toughness of solid balsa used for cores of sandwich composites
Authors: Mohammadi Meisam Shir , Nairn John A
Published: September 2013

To better understand the suitability of balsa wood as a core material for sandwich composites, this paper presents a detailed study of the fracture properties of balsa. The experiments looked at mode I, mode II, and mixed-mode fracture with crack growth both parallel and perpendicular to the wood grain direction. The experiments monitored toughness as a function of crack growth to record crack resistance or R curves. The mode I toughness was lower than most other wood species, but considering its low density, the toughness of balsa is higher than previously expected. The mode I toughness increased as a function of crack growth due to a fiber-bridging process zone at the crack tip. The mode II toughness was higher than mode I toughness, but was much less affected by fiber bridging. The mixed-mode failure envelope had an unusual shape, which could be explained by an influence of fiber bridging. Overall, the toughness of balsa is adequate for sandwich composite core materials and likely better than some alternative core materials.
Towards a real comparison of left-right indices
Authors: Franzmann Simon T
Published: September 2013

In a recent article in Party Politics, Detlef Jahn proposed an alternative way of generating left–right scores using data from the Comparative Manifestos Project (CMP). Despite presenting innovative ideas, the article requires comment and correction. First, Jahn’s claim of a deductive approach is not convincing. He proceeds at least partly inductively. Furthermore, he ignores the theoretical ground of the competing approaches. Second, and more importantly, the central criterion by which to evaluate different approaches should be construct validity; however, Jahn does not conduct a full test of the construct validity. In this comment, I first explain the theoretical base of different approaches in generating left–right position scores using CMP. Second, I conduct a test of construct validity using not only expert data but also survey data. The results clearly suggest that approaches using a context-specific scheme for determining left–right issues are superior to the existing alternatives. This comment should be of interest to all scholars concerned with the question of how to create valid party position indicators.
Workplace stress in community pharmacies in England: associations with individual, organizational and job characteristics
Authors: Jacobs Sally , Hassell Karen , Ashcroft Darren , Johnson Sheena , O’Connor Elinor
Published: September 2013

Objectives

To describe the levels of workplace stress that community pharmacists perceive and to examine associations with individual, organizational and job characteristics.

Methods

A cross-sectional mailed survey of 2000 randomly selected community pharmacists practising in England incorporating a validated organizational stress screening tool (ASSET).

Results

Response rate was 48%. Community pharmacists reported significantly higher levels of stress than other health care workers for seven out of eight work-related stressors. Regression analyses demonstrated significant associations between a number of individual, organizational and job characteristics and stress. Long working days, being a pharmacy manager and working for large multiples were associated with higher reported levels of stress across a number of work-related stressors including work overload, control and the job itself. However, self-reported measures of workload (such as dispensing volume) were not associated with higher stress levels.

Conclusions

The growth in corporate ownership of community pharmacies, which is associated with more stressful working environments, together with current economic pressures could have consequences not only for the future well-being of pharmacists but also for patient safety.
Looking across three generations of Alaska Natives to explore how culture fosters indigenous resilience
Authors: Wexler Lisa
Published: September 2013

Research has established connection between indigenous culture—often described in terms of cultural identity, enculturation, and participation in traditional activities—and resilience, the process by which people overcome acute and ongoing challenges. Despite correlations between culture and resilience, research has seldom described the ways these concepts are linked in indigenous people’s narratives. Furthermore, little attention has been paid to the affect of historical trauma on different generations’ understanding and deployment of “culture” in the context of hardship. This project, conducted in the summer of 2008 in an indigenous Arctic community, focuses on narratives from three generations who have experienced different degrees of cultural suppression in their lifetimes. From this starting point, the study explores how individuals make meaning and take strength from particular notions of culture, and illuminates the ways each generation accesses and deploys their cultural understandings in the face of hardship. By identifying the similarities and differences in both the challenges and sources of strength for each generation, the paper highlights how understandings of culture are shaped by historical experiences and modified through time. The differing ways that culture fosters strength, purpose, and fortitude (or does not) in indigenous young people’s, adults’ and Elders’ life stories provide clues for enhancing indigenous youth resilience. Findings suggest that “culture” can galvanize Inupiaq people’s sense of identity, feeling of commitment, and purpose, all of which are protective. However, young people need support in developing particular ideas around cultural identity and group membership that can contribute to resilience.
Active learning in the online environment: The integration of student-generated audio files
Authors: Bolliger Doris U , Armier David Des
Published: September 2013

Educators have integrated instructor-produced audio files in a variety of settings and environments for purposes such as content presentation, lecture reviews, student feedback, and so forth. Few instructors, however, require students to produce audio files and share them with peers. The purpose of this study was to obtain empirical data on graduate students’ perceptions of the integration of student-generated audio files within the context of online, asynchronous course delivery and to gain an understanding of how this approach impacted their perceived satisfaction, engagement, connectedness, learning, and utilization. Results indicate students were satisfied with this instructional approach. The integration of student-generated audio files fostered their engagement and involvement, assisted them in effectively connecting and communicating with peers, and increased their learning. Some drawbacks to this approach are detailed.
Pragmatic rational planning: Comparing Shanghai and Chicago
Authors: Wang Lan , Hoch Charles
Published: September 2013

Planners in Shanghai and Chicago inhabit contrasting institutional planning systems. Despite these differences, the professional planners exhibit a shared commitment to basic rational planning doctrine. But most importantly, they practice a kind of pragmatic planning that adapts the principles of sustainability and an inclusive public interest to everyday planning conduct. Professional planners share a kind of practical intelligence acquired through university education that they use to pragmatically pursue shared planning norms within different institutional settings.
Application of teletraffic engineering modelling techniques for studying smart lighting systems for energy saving
Authors: Li XJ
Published: September 2013

Limited natural energy resources compel humankind to search for efficient utilization of energy, and thus increasing number of fluorescent lamps are adopted for lighting systems. However, previous study showed that there exists a tradeoff between energy saving and lifespan for fluorescent lamps. Consequently, it becomes an important topic on how to design an efficient and effective automatic control algorithm in illuminating engineering. This problem has been traditionally studied by conducting surveys and experiments, which are unavoidably costly and rather time-consuming. This paper presents a novel application of teletraffic engineering modelling techniques in studying automatic lighting control systems. A queuing model is proposed to study typical lighting systems and a simple closed-loop algorithm is illustrated to effectively adapt the system control parameters. Through computer simulation, it is shown that the proposed method provides an alternative way of studying lighting systems in a cost-effective manner, while providing adequate accuracy.
Sky vault partition for computing daylight availability and shortwave energy budget on an urban scale
Authors: Beckers B , Beckers P
Published: September 2013

The objective of this work is to propose to the urban physics community an optimal sky vault partition able to support most existing applications, either in daylight availability evaluation or in shortwave energy budget estimation. This partition is explained and justified. Its refinement is examined and analysed with respect to the studies performed today at urban level. The solution of the analyses is obtained in two steps: the heaviest part is the solution of the urban interreflection problem, while the second step is very fast and can be achieved in interactive mode. It consists in computing the thermal or illumination loads which will be used as coefficients of a recombination of the first step results. The urban interreflection problem is independent of this process and can be obtained with various existing techniques, such as the radiosity method.
Viscoelastic and thermal behaviour of flax preforms reinforced epoxy composites
Authors: Muralidhar BA
Published: September 2013

This study investigates the thermal and viscoelastic properties of flax preform reinforced epoxy composites. Plain woven flax fabric and 1 × 1 weft rib knitted structures were used as reinforcements and flax preforms reinforced epoxy composites were produced using hand lay-up method. Thermogravimetric analysis (TGA) indicates a decrease in thermal stability of the matrix polymer with the incorporation of flax woven and knitted preforms. The dynamic mechanical analysis revealed a higher storage modulus for woven preform reinforced composite compared to knitted preform reinforced composites. The storage modulus was found to decrease with temperature in all cases. Loss modulus showed shifts in the ( Tg) compared to virgin epoxy, with the addition of flax preforms as reinforcing phase, which indicate that preforms plays an important role with respect to Tg. Single tan δ peaks were observed for all the composite samples tested. The tan δ peak height was maximum for virgin epoxy matrix, indicating that there is a large degree of mobility, thus good damping behaviours. However, lower peaks were observed for both woven and knitted preform reinforced composites. With respect to the viscoelastic properties the rigidity and endurance of the fibres are highly affected by thermal treatment at temperatures above 70℃ and up to 100℃.
Hybrid Treatment in a Patient With Acute Aortic Syndrome and an Aberrant Right Subclavian Artery
Authors: Folkmann Sandra , Waldenberger Ferdinand , Weiss Gabriel , Mertikian Gerard , Moidl Reinhard , Gorlitzer Michael , Grabenwoeger Martin
Published: September 2013

A 57-year-old man was admitted to our department with recent onset of chest pain. Computed tomography (CT) scans revealed an acute aortic syndrome manifested by a penetrating atherosclerotic ulcer and contained rupture at the level of origin of an aberrant right subclavian artery. A combined vascular and endovascular approach was selected. The entire arch was rerouted, a reversed bifurcated Dacron prosthesis was placed, and a bypass was created between the right common carotid artery and the lusorian artery, followed by thoracic endovascular aortic repair. The clinical course was uneventful. The CT scan obtained after the procedure revealed regular supra-aortic perfusion and complete exclusion of the complex lesion.
The role of ultrasound in the diagnosis of a rare case of chronic Shistosoma haematobium in the United Kingdom
Authors: Turpin Alexandra , Lapham Roger , Joyce Adrian , Wolstenhulme Stephen
Published: September 2013

This case report discusses the use of ultrasound in the diagnosis and morbidity assessment of the urogenital form of schistosomiasis. Although previously considered rare in the United Kingdom, the incidence of Schistosoma haematobium has increased in western countries. The ultrasound findings of this report are correlated with existing ultrasound criteria and found to be educational in regard to patient management. This case highlights the importance of obtaining a comprehensive patient history in order to narrow potential differential diagnoses and facilitate appropriate referral.
Correlation of B-mode sonography and compression elastography for diagnosis of tendon degeneration: a pictorial review
Authors: Horton Laura
Published: September 2013

A pictorial review of 76 examinations of the extensor carpi ulnaris tendon using compression sonoelastography in conjunction with B-mode ultrasound imaging is presented here. A comparison of these two technologies is presented and the corresponding images were evaluated to determine whether there is correlation between the two technologies. Furthermore, the possibility that tendon degeneration and softening can be diagnosed earlier than has previously been possible using both of these technologies rather than B-mode imaging alone was explored and the results presented. Patients with unilateral or bilateral extensor carpi ulnaris tenosynovitis were scanned as part of a larger rheumatoid arthritis research study, which included extensor carpi ulnaris evaluation as part of its protocol. B-mode images were acquired with corresponding compression sonoelastography colour map, the region of interest being that portion of the tendon between the ulnar styloid and the insertion at the fifth metacarpal base. Seven paired images from different patients, which represent the varying appearances of extensor carpi ulnaris tenosynovitis seen in the study cohort are shown. Healthy tendons have a uniform hyperechoic fibrillar pattern longitudinally on B-mode imaging with predominantly mid-blue overlay on elastography. Tenosynovitis is shown on grey scale to have the usual appearances of loss of fibrillar echotexture and hypoechoic mucoid degeneration with the elastographic colour map showing predominantly red, yellow and green areas of tendon softening. There appears to be good correlation between the B-mode images and the elastographic overlay. The additional tissue characteristics yielded by sonoelastography in relation to tendon and peritendinous soft tissue elasticity may provide clinicians with information that could alter patient management. This technique shows promise in the earlier detection of tendon degeneration.
Sheffield spinal pathway audit cycle – pathways, mountains and the view from the top
Authors: Hart Ollie , Ryton Beverly A
Published: September 2013

There is good evidence to suggest that a proactive stratified approach to management of spinal pain, taking into account psychosocial as well as biological factors, can realise significant savings for health-care systems and perhaps more importantly, health benefits for society at large. This audit cycle report captures data on quality of care and patient flows before and after the mandating of changes to the referral pathways in primary care. These included the introduction of a simple one-sided referral proforma, bounce back of inappropriate referrals from secondary care to physiotherapy lead teams and implementation of the STarT tool, as a decision aid in primary care.
An Analysis of Collaboration in a State-Level Interagency Transition Team
Authors: Noonan Patricia M. , McCall Zach A. , Zheng Chunmei , Gaumer Erickson Amy S.
Published: September 2013

Interagency collaboration facilitates strong linkages to adult agencies, which improves adult outcomes among youth with disabilities (Kohler & Field, 2003; Repetto, Webb, Garvan & Washington, 2002). State-level transition teams increase collaboration, reduce duplication of resources, improve professional development, and heighten the cross-flow of information (Blalock, 1996; Wehman, 1998). Using social network (Daly, 2010) and focus group analysis (Krueger & Casey, 2000), this mixed methods study examined changes in collaboration, as well as collaborative characteristics and activities, among members of one state-level transition team. Analysis of the social network indicated a significant increase in the network density. Furthermore, focus group results indicated a range of collaborative strategies that built group cohesion and facilitated movement toward improving transition and student outcomes.
The Postsecondary Educational Plans of Rural Youth With Disabilities and Their Nondisabled Peers
Authors: Weiss Margaret P. , Hutchins Bryan C. , Meece Judith L.
Published: September 2013

A national sample of students with disabilities and their nondisabled peers in rural high schools responded to a survey about their postsecondary plans and how they were preparing for them. The study included 3,318 11th- and 12th-grade students from 73 randomly selected schools. Findings indicate that 78.5% of students with disabilities and 90.7% of their nondisabled peers plan to continue their education after high school. Only 4.5% of students with disabilities were enrolled in a college preparatory program. A greater percentage of students with disabilities participated in career exploration activities such as job mentoring, internships, and cooperative education programs than expected, and they found teachers and school staff important sources of information. Implications of these findings are discussed.
A Perspective on Revising OSEP Indicator 14
Authors: Vitelli Edward M.
Published: September 2013

Indicator 14 obligates states to track, for a period of 1 year after leaving high school, the educational and employment outcomes of students with disabilities. The purpose of the indicator is to improve transition services that prepare this population for postschool adult living. For most students, the indicator’s tracking period only permits the collection of data through the end of adolescence. As such, transition programs are using data from adolescents to prepare students for adulthood. Given the significant differences between adults and adolescents (e.g., neurological, behavioral, functional), this dilemma should be addressed to create more relevant and effective transition programming. Several changes are recommended, including the extension of the tracking period as well as the inclusion of additional outcome categories to monitor, bringing the indicator into alignment with the definition of transition services provided in the Individuals With Disabilities Education Act.
In Other Sources
Authors: Konrad Moira , Schnorr Crystalyn , Freeman Shaqwana W. , Flynn Susan D. , Cease-Cook Jennifer , Diegelmann Karen M. , Scroggins La’ Shawndra C. , Toms Ozalle M. , Keesey Susan
Published: September 2013

This column provides brief summaries of transition-related articles published in 2011 in other professional journals. The 27 articles included descriptive, experimental, and qualitative research as well as program descriptions, conceptual papers, and practitioner pieces. All areas of Kohler’s Taxonomy for Transition Programming were addressed: family involvement, interagency collaboration, program structure, student development, and student-focused planning.
Reflections on the Past and Thoughts About the Future of the Transition Field
Authors: Bullis Michael
Published: September 2013

This article describes the author’s personal view of the secondary special education and transition field, its shortcomings, and its future within the context of our modern society.
Student Engagement and Leadership of the Transition Planning Process
Authors: Martin James E. , Williams-Diehm Kendra
Published: September 2013

The Council for Exceptional Children’s Division on Career Development and Transition (DCDT) has been a longstanding leader and advocate in the field of secondary education for students with disabilities. This paper traces the history of student engagement in transition planning primarily through the lens of DCDT’s journal Career Development for Exceptional Individuals, now known as Career Development and Transition for Exceptional Individuals. Student engagement in the transition planning process implies meaningful student participation in Individualized Education Plan (IEP) meetings, including both student leadership of IEP meetings and presenting IEP results during meetings, student engagement in the transition planning process, participation in and understanding of transition assessment results, and the attainment of annual IEP transition goals. The idea of student engagement in the transition planning process was initially delivered in a larger context, and then across the years, the topic became the primary focus of specific articles. We trace this development and conclude by speculating where student engagement in transition planning will go in the future. Suggestions are offered for both research and practice.
Thirty-Five Years of Transition Topics
Authors: Madaus Joseph W. , Gelbar Nicholas W. , Dukes Lyman L. , Faggella-Luby Michael , Lalor Adam R. , Kowitt Jennifer S.
Published: September 2013

A systematic review was conducted of 581 articles published in 76 issues of Career Development and Transition for Exceptional Individuals from the journal’s initial issue in 1978 to the final issue of its 35th year in 2012. Articles were coded based on inclusion of original or secondary data and if not, what type of information the article contained. In the case of articles that presented data, statistics were collected related to sample demographics and the location of the study. In addition, the topic of each article was coded. The most common topical areas were program descriptions and professional development. Trends throughout the analysis are discussed to forecast topical areas needing study as the journal goes forward.
An Assessment of Publication Productivity in Career Development and Transition for Exceptional Individuals
Authors: Unger Darlene D. , Rumrill Phillip D.
Published: September 2013

This literature review examined publication patterns in the journal of Career Development and Transition for Exceptional Individuals across 35 years of publication. Overall, 732 contributors affiliated with 267 organizations were identified in our analysis of 436 articles. Frequency counts identified the most productive scholars in terms of number of articles authored and their institutional affiliation. Twenty-three individuals, predominately representing colleges and universities, contributed 6 or more articles. Findings reflect the collaborative nature of scholarship in career development and transition and an overall trend toward multiple authored publications. There is a need to engage or support individuals affiliated with local or state education agencies, vocational rehabilitation, and community rehabilitation programs, or individuals working outside of the United States in generating scholarship, as these groups were underrepresented in our findings. Suggestions for increasing authorship representation reflecting all transition stakeholders and the importance of collaboration in building the transition and career development knowledge base are discussed.
Transition From School to Work
Authors: Wehman Paul
Published: September 2013

As children become teenagers and move into early adulthood, there are many transitions they face. For young people with disabilities, this is no different except that there are invariably additional complex challenges that must be overcome. Evidence-based research is the foundation for best transition practices, but too many studies seem abstract, distant, and far removed from their classroom or school world. This article seeks to overcome the abstract by describing evidence-based transition research and recent findings. Teachers’ classroom needs are highlighted with special emphasis on how research can be useful for them on a day-to-day basis. Finally, we highlight six guidelines for helping implement best practices in transition.
Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia
Authors: Willems Lise , Jacque Nathalie , Jacquel Arnaud , Neveux Nathalie , Trovati Maciel Thiago , Lambert Mireille , Schmitt Alain , Poulain Laury , Green Alexa S. , Uzunov Madalina , Kosmider Olivier , Radford-Weiss Isabelle , Moura Ivan Cruz , Auberger Patrick , Ifrah Norbert , Bardet Valérie , Chapuis Nicolas , Lacombe Catherine , Mayeux Patrick , Tamburini Jérôme , Bouscary Didier
Published: September 2013

Key Points

Glutamine removal and knockdown of the glutamine transporter SLC1A5 have antileukemic activity in AML. The glutaminase activity of l-asparaginase inhibits mTORC1 and protein synthesis and induces a strong autophagy in AML.
Phase 2 dose-expansion study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma
Authors: Wang Michael , Martin Tom , Bensinger William , Alsina Melissa , Siegel David S. , Kavalerchik Edward , Huang Mei , Orlowski Robert Z. , Niesvizky Ruben
Published: September 2013

Key Points

Presented are results from the phase 2 dose-expansion study of the combination of carfilzomib, lenalidomide, and dexamethasone (CRd). CRd was well tolerated with robust, rapid, and durable responses.
Embryonic remnants of intercentra and cervical ribs in turtles
Authors: Werneburg Ingmar , Maier Wolfgang , Joyce Walter G.
Published: September 2013

A broad sample of extant turtles possesses a series of paired bones in the neck that are situated between the cervical vertebrae. These paired bones were originally proposed to be cervical rib remnants, but have more recently been interpreted as vestiges of intercentra. Here, we document, for the first time, the neck development of a pleurodire turtle, Emydura subglobosa, and identify blastematous structures, which partially recapitulate the ribs and intercentra of the plesiomorphic tetrapod condition. We identify blastematous “bridges” between intercentra and the corresponding ribs, which we homologize with the vestiges visible in extant turtles and with the remnant parapophyseal articulation processes of the intercentra of some stem taxa. Only the unpaired, median part of the intercentrum of the atlas is retained in adult turtles, but intercentra are recapitulated along the entire vertebral column during development; they are embedded in the cervical myosepta and serve as attachment sites for neck musculature. We also identify two rib rudiments in the occipital region, which may indicate that at least two vertebrae are integrated into the cranium of turtles in particular, and of amniotes in general.
CSF p-Tau levels in the prediction of Alzheimer's disease
Authors: Kandimalla Ramesh J. L. , Prabhakar Sudesh , Wani Willayat Yousuf , Kaushal Alka , Gupta Nidhi , Sharma Deep Raj , Grover V. K. , Bhardwaj Neerja , Jain Kajal , Gill Kiran Dip
Published: September 2013

The two hallmarks of Alzheimer's disease (AD) are neurofibrillary tangles and amyloid plaques. Neurofibrillary tangles are formed due to the hyperphosphorylation of tau protein. There is an urgent need to develop a reliable biomarker for the diagnosis of AD. Cerebrospinal fluid (CSF) is surrounding the brain and reflects the major neuropathological features in the AD brain. Diagnosis, disease progression and drug actions rely on the AD biomarkers. Mainly CSF tau and phosphorylated tau (p-Tau) have been observed to serve the purpose for early AD. Keeping in view the early appearance of p-Tau in CSF, we analyzed p-Tau levels in 23 AD, 23 Non AD type dementia (NAD), 23 Neurological control (NC) and 23 Healthy control (HC) North Indian patients. The levels of p-Tau were found to be increased in AD patients (67.87±18.05 pg/ml, SEM 3.76) compared with NAD (47.55±7.85 pg/ml, SEM 1.64), NC (34.42±4.51 pg/ml, SEM 0.94) and HC (27.09±7.18 pg/ml, SEM 1.50). The resulting sensitivity for AD with NAD was 80.27% whereas with respect to the NAD, NC and HC was 85.40%. Therefore elevated levels of p-Tau in AD can be exploited as a predictive biomarker in North Indian AD patients.
Approximability of Robust Network Design
Authors: Olver Neil , Shepherd F. Bruce
Published: September 2013

We consider robust (undirected) network design (RND) problems where the set of feasible demands may be given by an arbitrary convex body. This model, introduced by Ben-Ameur and Kerivin [Ben-Ameur W, Kerivin H (2003) New economical virtual private networks. Comm. ACM 46(6):69–73], generalizes the well-studied virtual private network (VPN) problem. Most research in this area has focused on constant factor approximations for specific polytope of demands, such as the class of hose matrices used in the definition of VPN. As pointed out in Chekuri [Chekuri C (2007) Routing and network design with robustness to changing or uncertain traffic demands. SIGACT News 38(3):106–128], however, the general problem was only known to be APX-hard (based on a reduction from the Steiner tree problem). We show that the general robust design is hard to approximate to within polylogarithmic factors. We establish this by showing a general reduction of buy-at-bulk network design to the robust network design problem. Gupta pointed out that metric embeddings imply an O(log n)-approximation for the general RND problem, and hence this is tight up to polylogarithmic factors.

In the second part of the paper, we introduce a natural generalization of the VPN problem. In this model, the set of feasible demands is determined by a tree with edge capacities; a demand matrix is feasible if it can be routed on the tree. We give a constant factor approximation algorithm for this problem that achieves factor of 8 in general, and 2 for the case where the tree has unit capacities. As an application of this result, we consider so-called H-tope demand polytopes. These correspond to demands which are routable in some graph H. We show that the corresponding RND problem has an O(1)-approximation if H admits a stochastic constant-distortion embedding into tree metrics.
Single-Nucleotide Polymorphisms and Other Mismatches Reduce Performance of Quantitative PCR Assays
Authors: Lefever Steve , Pattyn Filip , Hellemans Jan , Vandesompele Jo
Published: September 2013

BACKGROUND

Genome-sequencing studies have led to an immense increase in the number of known single-nucleotide polymorphisms (SNPs). Designing primers that anneal to regions devoid of SNPs has therefore become challenging. We studied the impact of one or more mismatches in primer-annealing sites on different quantitative PCR (qPCR)-related parameters, such as quantitative cycle (Cq), amplification efficiency, and reproducibility.

METHODS

We used synthetic templates and primers to assess the effect of mismatches at primer-annealing sites on qPCR assay performance. Reactions were performed with 5 commercially available master mixes. We studied the effects of the number, type, and position of priming mismatches on Cq value, PCR efficiency, reproducibility, and yield.

RESULTS

The impact of mismatches was most pronounced for the number of mismatched nucleotides and for their distance from the 3′ end of the primer. In addition, having ≥4 mismatches in a single primer or having 3 mismatches in one primer and 2 in the other was required to block a reaction completely. Finally, the degree of the mismatch effect was concentration independent for single mismatches, whereas concentration independence failed at higher template concentrations as the number of mismatches increased.

CONCLUSIONS

Single mismatches located >5 bp from the 3′ end have a moderate effect on qPCR amplification and can be tolerated. This finding, together with the concentration independence for single mismatches and the complete blocking of the PCR reaction for ≥4 mismatches, can help to chart mismatch behavior in qPCR reactions and increase the rate of successful primer design for sequences with a high SNP density or for homologous regions of sequence.
A Nova Gestão Pública como indutora das atividades de Engenharia de Produção nos órgãos públicos
Authors: Jesus Igor Rosa Dias de , Costa Helder Gomes
Published: September 2013

O propósito deste trabalho é o de mostrar como a Nova Gestão Pública, ao incorporar ferramentas e pontos de vista oriundos da iniciativa privada, abre espaço para maior atuação dos engenheiros de produção no Estado. Na introdução é apresentada uma contextualização histórica da evolução da gestão pública, desde o modelo patrimonialista, passando pelo modelo burocrático e pelo gerencial, até a assunção da Nova Gestão Pública. É também apresentada uma contextualização histórica da própria Engenharia de Produção. A busca por interfaces entre esses dois campos do conhecimento se deu a partir de uma investigação teórica, na qual se procurou entender quais práticas de gestão estariam associadas, simultaneamente, a elementos da Engenharia de Produção e da Nova Gestão Pública. Os resultados dessa investigação nos mostram que essa interface atinge todos os elementos da Nova Gestão Pública e todas as subáreas da Engenharia de Produção.
Relatórios de sustentabilidade segundo a Global Reporting Initiative (GRI): uma análise de correspondências entre os setores econômicos brasileiros
Authors: Oliveira Murilo de Alencar Souza , Campos Lucila Maria de Souza , Sehnem Simone , Rossetto Adriana Marques
Published: September 2013

O presente artigo tem por objetivo principal apresentar o nível de adesão e o volume de publicações dos relatórios de sustentabilidade das empresas brasileiras conforme as diretrizes da Global Reporting Initiative (GRI) entre 2000 e 2008. Para a análise, foram definidas 5 variáveis de estudo: i) Setor econômico de atuação das empresas; ii) Ano de adesão às diretrizes; iii) Nível de aplicação das diretrizes; iv) Existência de ações negociadas em segmentos da BM&FBOVESPA; e v) Participação na composição do índice de sustentabilidade empresarial (ISE) da BM&FBOVESPA. Quanto aos procedimentos metodológicos, foram aplicadas análises por correspondências simples e múltipla entre os setores de atuação econômica das empresas publicantes e as 5 variáveis de estudos definidas. Os resultados mostram que o universo de organizações que publicaram relatórios socioambientais até 2008 ainda é reduzido. Contudo, observa-se crescente adesão, demonstrada pelo número de publicações, sobretudo na Europa. As empresas brasileiras responderam por metade do volume de publicações em 2008 na América Latina e o setor de energia liderou esse processo no país com 35% da amostra.
Movimentos de resistência no Sistema Único de Saúde (SUS): a participação rizomática
Authors: Quintanilha Bruna Ceruti , Sodré Francis , Dalbello-Araujo Maristela
Published: September 2013

A participação social no SUS assegura a importância da interferência do usuário para sua construção. Entretanto, postulamos que existem várias formas de manifestação da participação, para além das já instituídas, que afirmamos serem movimentos de resistência, denominados de participação rizomática. Com o intuito de mapear sua ocorrência no cotidiano de unidades de saúde, criamos estratégias e instrumentos inscritos na abordagem qualitativa em pesquisa, inspirados na postura cartográfica e na análise da implicação. Os movimentos percebidos foram agrupados em três tipos de analisadores: os ditos, os mal ditos e os não ditos. Consideramos as condições que propiciaram a ocorrência e os efeitos produzidos por eles. Sugerimos que os movimentos de participação rizomática devem ser entendidos como pontos de análise dos serviços de saúde, pois sua explicitação possibilita repensar as práticas instituídas no SUS.
O subproduto social advindo das cotas raciais na educação superior do Brasil
Authors: Santos Hélio ,   Fundação Visconde de Cairu,  Brazil, Souza Marcilene Garcia de , Sasaki Karen ,   Instituto de Pesquisa da Afrodescendência,  Brazil,   Fundação Visconde de Cairu,  Brazil,   Centro Universitário Jorge Amado,  Brazil
Published: September 2013

Propõe demonstrar que as ações afirmativas no Brasil, no âmbito da universidade pública, originalmente reivindicadas pelo segmento negro, acabaram proporcionando um consistente subproduto social que beneficiou outros segmentos etnicorraciais. Para tanto, foi realizada uma análise de indicadores sobre a temática, com a qual pôde inferir as conclusões dos autores. Nesse sentido, o conceito de "subproduto social" deve ser entendido como a extensão de benefícios a outros grupos sociais que historicamente não sofreram desvantagens efetivas no Brasil. Trata-se de um artefato conceitual que possui dois componentes: o primeiro decorre da essência do debate ideológico sobre o tema e o outro tem um cunho perverso, pois transfere as vagas das "cotas raciais" não preenchidas para as "cotas sociais".
Durability enhancements using fabric formwork
Authors: Orr John , Darby Antony , Ibell Timothy , Evernden Mark
Published: September 2013

By replacing conventional concrete moulds with flexible sheets of permeable fabric, the construction of optimised concrete elements that provide material savings of up to 40% when compared with an equivalent strength prismatic member is possible. This paper details the results of recent tests undertaken at the Building Research Establishment Centre for Innovative Construction Materials at the University of Bath that demonstrate significant additional durability advantages for fabric-cast concrete. Using accelerated test methods, 50% average reductions in both the non-steady state chloride diffusion coefficient and carbonation coefficients were found when comparing concrete samples cast against permeable and impermeable surfaces. Sorptivity, surface hardness and scanning electron microscopy tests demonstrate further beneficial changes in the fabric-cast concrete. The combined results demonstrate that fabric formwork may be used to create structures optimised for strength and durability.