bluuebunny/crossref_metadata_2025 huggingface dataset:
Interpretation strategy for the MMPI-2 protocol – a case study of a patient with bipolar disorder during remission of hypomanic symptoms
Authors:   Wojewódzki Szpital dla Nerwowo i Psychicznie Chorych w Bolesławcu, Bolesławiec, Polska, Głowacka Amelia
Published: November 2021

The paper presents an exemplary strategy for interpreting MMPI-2 data. Due to the multitude of diagnostic tools, the complex nature of the questionnaire and the time-consuming analysis of the data obtained, all examples of interpretation may be helpful for a psychologist. Polish reports supporting the broad interpretation of the MMPI-2 are sparse. The presented case study illustrates an interpretative path replicable in any clinical psychological practice. The article is based on the official guidelines of the Psychological Test Laboratory of the Polish Psychological Association. They were developed by Marek Matkowski and Tomasz Kucharski, specialists dealing with the discussed tool, and represent individual diagnostic recommendations created under the supervision of experienced clinicians and a one-time consultation with MSc Andrzej Janiak. Respecting the original copyrights belonging to the Psychological Test Laboratory of the Polish Psychological Association in Poland, I recommend purchasing only official and authorised materials in the above-mentioned Laboratory and familiarising with its official position on the diagnostic path in MMPI-2.
Maternal and Infant Characteristics and Outcomes Among Women With Confirmed or Presumed COVID-19 During Pregnancy: 14 States and the District of Columbia
Authors: Martin Joyce , Osterman Michelle , Claudia Valenzuela
Published: November 2021

This report describes characteristics and selected pregnancy outcomes among mothers with and without confirmed or presumed COVID-19 during pregnancy by maternal age, educational attainment, race and Hispanic origin, and source of payment for the delivery for a 14-state and District of Columbia reporting area.
Mecanismos de acción de la microbiota oral en el desarrollo del cáncer. Revisión sistemática exploratoria.
Authors: López Matamala Consuelo , Romero Florencia , Sánchez Marcelo
Published: November 2021

En esta revisión sistemática exploratoria, presentamos la evidencia registrada en la literatura, de que la microbiota oral puede generar una acción carcinogénica, actuando a través de tres mecanismos principales: sobre el medio extracelular, activando vías de señalización intracelular y / o generando acción directa sobre el ADN, y que las principales bacterias estudiadas corresponden a Fusobacterium Nucleatum y Porphyromona Gingivalis. En la actualidad hay evidencia suficiente acerca de la asociación entre microbiota oral y distintos tipos de cáncer, sin embargo, no hay gran conocimiento de los mecanismos por los cuales esta microbiota participa en su desarrollo. Presentamos una recopilación de los diversos mecanismos de acción que utilizan las bacterias de la cavidad oral en el proceso de carcinogénesis en cuatro tipos diferentes de cáncer.
The acquisition of adverbs in child L3 French in Canada
Authors: Pirvulescu Mihaela , Hill Virginia , Nacif Nadia , Helms-Park Rena , Petrescu Maria
Published: November 2021

This paper1 focuses on the acquisition of adverbs in French L3 and aims to identify the possible role of transfer in this particular linguistic context. The data come from children born in Canada who speak Romanian as a heritage language and are exposed to English as the societal language as well as to French (L3) in school. The variable under scrutiny is the position of adverbs in light of Cinque’s (1999) universal hierarchy. The results indicate that children have nativelike competence for adverb placement in the three languages; however, some non-convergent uses arise in French signaling possible transfer of other parametric settings from Romanian. We suggest that this is a case of non-facilitative transfer due to structural similarity between Romanian and French.
A Fight Against the Dissemination of Deepfakes in Other Countries: Criminal and Criminological Aspects
Authors: Dremliuga Roman , Korobeev Alexander
Published: November 2021

The authors analyze a relatively new phenomenon of spreading realistic audiovisual fake materials (deepfakes). This socially dangerous phenomenon is not reflected in the Russian criminal legislation as a separate offence. At the same time, some countries have started developing a criminal policy in this sphere. The methodology of the study presupposes a comparative law analysis of current legislations of the USA, China and the European union regarding the liability for the dissemination of realistic audiovisual fakes. The analysis of criminal legislation is aimed at the identification and systematization of key approaches to criminalizing the dissemination of realistic audiovisual fakes in the countries that are the leaders in digitizing their social and economic life. It showed that there are radically different approaches to regulating criminal liability for the actions under consideration. The authors analyzed criminal policy of the United States at the federal and state levels on the criminal law protection against infringements through deepfakes. They found that the first action to be recognized as criminal is the use of realistic audiovisual fakes for electoral intervention. The legislations of some states strictly regulate the procedure of posting such content before elections, the most serious violations leading to criminal liability. Besides, the United States recognizes as criminally punishable the use of deepfakes for creating materials of intimate nature and for identity theft. The People’s Republic of China establishes liability, including criminal liability, for posting any fake realistic-looking audiovisual materials without mentioning that they are fake. Currently there are no special criminal law norms regulating liability for the dissemination of deepfakes in the law of the European Union. This action should be viewed as infringement of the lawful use of personal data. The authors give their assessment of some criminological characteristics of the analyzed publicly dangerous phenomenon in Russia and in the world. In spite of the relative novelty of the deepfake technology, realistic fake videos are quite common. The society supports the necessity of criminalizing this publicly dangerous action.
Raising Awareness of Agency to Address Climate Change: The Do One Thing (DOT) Strategy
Authors: Muller Irene , Wood Lesley
Published: November 2021

The United Nations Children's Fund 2008 report, Our Climate, Our Children, Our Responsibility, warned that children will suffer most from the effects of climate change. Environmental education is one way to prepare children to cope and enable them to educate their families and friends about the need to act now to minimise the danger climate change poses. This article reports on findings from a participatory action research project aimed at integrating education for sustainable development into the Grade 7 curriculum, with a specific focus on climate change. Critical participatory action research has a transformative intent, engaging participants in learning to cultivate a sense of purpose and increase their capacity to solve local problems. Learner responses to qualitative questionnaires and recorded discussions related to the Do One Thing (DOT) strategy were used to determine learning about climate change and enable both learners and community members to identify action for change. Thematic coding was used to evaluate the effectiveness of the DOT strategy in increasing awareness of agency and resultant learning. The findings indicate that not only did the learners gain knowledge about the causes and consequences of climate change but the potential of the learners and community members to identify possible actions for change was increased as well. We provide suggestions as to how teachers can use the DOT strategy as part of an action research approach to integrating environmental education for sustainable development in order to raise awareness of local environmental threats and encourage learners and their families to behave in a more environmentally friendly way. The explanation of the research process offered in this article also highlights how participatory learning activities can help engage learners as active agents in their own learning.
A Critical Approach to University-Community Partnerships: Reflecting on the Diverse Realities
Authors: Sathorar Heloise , Geduld Deldre
Published: November 2021

Postapartheid South Africa has seen a greater focus on community engagement by universities, and its inclusion as one of the core focus areas of higher education in addition to teaching and research. This focus on engagement with the community was ignited by a requirement to enhance the university's social responsibility through establishing partnerships with the communities it serves. Higher education institutions have traditionally positioned themselves in engagement projects as the singular organisation that has knowledge to offer when compared to what the community can offer. In this paper, we propose a critical engagement process to enhance collaboration in engagement projects. Our qualitative study resides in a critical theory paradigm, and we used drawings as well as narrative free writing to reflect and explore our perceptions regarding community engagement. We used the collaborative self-study methodology because it provides opportunities for critical and self-critical reflection that could lead us to discovering valuable insights, as well as provide suggestions on how to enhance university community partnerships. Our findings suggest that, despite legislation and efforts to enhance university community engagement, this remains a contested space where power relations, inequality, and claims to knowledge ownership continue to pose challenges.
Using Photographs and Memory-Work to Engage Novice Teachers in Collaborative Learning About Their Influence on Learner Behaviour
Authors: Luthull Khulekani
Published: November 2021

This article offers an account of using photographs and memory-work as a visual participative method in research conducted by a deputy principal with novice teachers in a South African primary school. The study was prompted by observations of how novice teachers struggled to manage learner behaviour in socially just and compassionate ways. It aimed to help novice teachers express the uncertainties and challenges they encounter, and prompt candid discussions on learner behaviour. The article shows how visual participative methods can facilitate collaborative learning with novice teachers. Additionally, it illustrates how the novice teachers came to see their critical role in influencing learner behaviour and the value of positive teacher-learner relationships in supporting learner behaviour. This work will be valuable to educational researchers in diverse contexts interested in growing their participative research methods repertoire. Furthermore, it illustrates how working with photographs and memory-work can facilitate the expression of participants' viewpoints and understandings and intensify educational researchers' learning from and with others in the interests of social change.
CNR2 GENE AND CANNABIS USE INTERPLAY MODULATES MANIPULATIVE ABILITIES IN FIRST-EPISODE OF PSYCHOSIS
Authors: Oscoz Irurozqui Maitane , Guardiola-Ripoll Maria , Almodóvar-Payá Carmen , Guerrero-Pedraza Amalia , Pomarol-Clotet Edith , Fatjó Mar
Published: November 2021

1. Objectives: While endocannabinoid system seems to be involved in processes underlying psychosis, research about Cannabinoid Receptor 2 gene (CNR2) is scarce and inconclusive. Some few reports indicate that CNR2 plays a role in psychiatric conditions, including depression or drug addiction (Onaivi et al., 2009). We aimed to evaluate the role of CNR2 and its interplay with cannabis on cognition and clinical symptoms in patients with a first-episode of psychosis (FEP). 2. Materials and Methods: the sample comprised 50 Caucasian individuals with a FEP (mean age(sd)=26.14(6.55) years, 76% males, 58% cannabis users). There were no differences in age, sex, premorbid IQ and antipsychotic dose between cannabis users (CU) and non-users (CNU). Neuropsychological (premorbid IQ - TAP-E, current IQ - WAIS, memory - WMS, executive function - BADS) and clinical (psychotic symptoms - PANSS, general functioning - GAF) scales were administered. Genetic variability was assessed by genotyping one Single Nucleotide Polymorphism (SNP) in CNR2 gene (rs2501431) (qPCR, TaqMan). 3. Results and conclusions: genotypic frequencies did not differ between cannabis users and non-users. CNR2 was not associated with PANSS scores.; however, it showed a differential effect on the performance IQ (measured by the matrix reasoning test - WAIS), conditional to the cannabis use (beta=0.73, p=0.02),. In particular, cannabis non-users with the AA genotype (23.53%) showed higher scores (mean(sd)=10.25 (1.87)) than those with at least one copy of the G allele (76.47%, mean(sd)=6.05(0.99); while cannabis users showed scores in the opposite direction (AA (42.31%): 8.21(1.09) and GG/GA (57.69%): 10.28(0.92)). Our results align with previous studies reporting the association of the CNR2 gene with psychiatric diseases (Ishiguro et al. 2007; Onaivi et al., 2008) adding evidence on the interplay of this gene with cannabis use on cognitive outcomes in first-episode psychosis. However, evidence is still scant, and further investigation in larger samples is needed.
SOMATIZACIÓN, DEPRESIÓN Y ANSIEDAD COMO PREDICTORES DEL CONSUMO INTENSIVO DE ALCOHOL EN JÓVENES
Authors: González Bella María , Vidal Claudio , Parrado Alberto , Carmona José , Conde Concepción , Fernández Fermín
Published: November 2021

Objetivo: El objetivo del presente estudio ha sido examinar el valor predictivo de la somatización, depresión y ansiedad en el consumo intensivo de alcohol en una muestra comunitaria de adultos jóvenes. Método: Estudio longitudinal en el que se accedió a 360 jóvenes de 18-25 años mediante muestreo dirigido a poblaciones diana (edad media= 21.15; DT= 2.23; Mujeres: 50.6%). Los jóvenes recibieron una gratificación de 15 euros mediante un cheque de compra para Amazon por participar en el estudio. El 39.9% (n=133) cumplimentó el cuestionario de seguimiento transcurridos dos meses desde la primera entrevista. En el seguimiento se preguntó por frecuencia de atracones de alcohol y borracheras en los dos meses previos. El cuestionario inicial incluyó el Inventario breve de síntomas (Brief Symptom Inventory; BSI-18; Derogatis y Melisaratos, 2000), utilizado para medir distrés psicológico, y compuesto por tres dimensiones: somatización, depresión y ansiedad. Se llevaron a cabo dos modelos de regresión lineal múltiple para predecir el consumo de intensivo de alcohol (borracheras y atracones). Resultados: Los resultados han mostrado que incrementos en la ansiedad se han relacionado con una mayor frecuencia de borracheras (β=.455, p<.000) y atracones (β=.526, p<.000), sin embargo, niveles altos en depresión predijeron una menor frecuencia de éstas (borracheras: β=-.351, p<.000; atracones: β=-.360, p<.001). Los resultados indicaron que la ansiedad y la depresión explicaron un 11% y 16% de la varianza de las borracheras y los atracones, respectivamente. Conclusiones: Estos hallazgos sugieren que la ansiedad y la depresión son factores que deben ser considerados para el desarrollo de programas de prevención y tratamiento entre consumidores de alcohol. Nota. Este proyecto (PI-0503-2018, IP: Fermín Fernández Calderón) ha sido financiado por la I+D+i biomédica y ciencias de la salud en Andalucía en la convocatoria para proyectos de investigación en salud de 2018.
RELACIÓN ENTRE EVENTOS TRAUMÁTICOS Y EL TRASTORNO POR USO DE SUSTANCIAS. ESTUDIO DESCRIPTIVO
Authors: Talisa Rebeca , Iñiguez Judith , Rigau Núria , Serrano Domènec
Published: November 2021

INTRODUCCIÓN Y OBJETIVOS Existe evidencia en la asociación entre el trastorno por uso de sustancias y la presencia de eventos traumáticos, no habiéndose encontrado hasta la fecha relación entre tipo específico de trauma y la sustancia consumida. Por ese motivo, el objetivo principal del presente estudio es valorar la relación entre la presencia de Trastorno por Uso de Sustancias y la presencia de eventos traumáticos de los pacientes ingresados en la Unidad de Patología Dual del Parc Hospitalari Martí i Julià. MATERIAL Y MÉTODOS Se ha realizado un estudio descriptivo con una muestra de 25 pacientes. Los datos fueron recogidos de forma retrospectiva respecto a las características sociodemográficas, clínicas, relacionadas con el uso de sustancias y sobre la presencia de eventos traumáticos. Para ello, se ha utilizado el programa estadístico SPSS representando las variables mediante el número de casos (N) y el porcentaje (%) dadas las características cualitativas de las mismas. Para valorar la asociación entre presencia de evento traumático y trastorno por uso de sustancias, se ha realizado un análisis de tipo bivariante mediante el test exacto de Fisher, representando los datos con el número total (N), porcentajes (%) y el p valor para la significación estadística. RESULTADOS Se observa una clara tendencia a la presencia de eventos traumáticos en los pacientes con trastorno por uso de sustancias independientemente del tóxico de consumo, observándose los traumas de tipo indirecto como principales. No obstante, no se ha encontrado una relación estadísticamente significativa entre el tipo de trauma y el tipo de tóxico consumido. CONCLUSIONES Debería considerarse la exploración directa de la presencia de eventos traumáticos en los pacientes con Trastorno por Uso de sustancias. Estudios de mayor tamaño muestral serían necesarios para valorar la asociación real entre el tipo de evento traumático y el tipo de tóxico de consumo.
ABSTINENCIA A ALCOHOL DURANTE EL CONFINAMIENTO EN ESPAÑA: ¿QUÉ NOS DICEN LAS ALCOHOLURIAS DE ETILGLUCURÓNIDO?
Authors: Barrio Giménez Pablo , Baldaquí Nuria , Andreu Magalí , Gual Antoni
Published: November 2021

Objetivos: Evaluar el impacto de la COVID-19 y el confinamiento domicliario en las tasas de recaída de pacientes con trastorno por uso de alcohol (TUA). A diferencia de estudios previos hechos mediante encuestas, nos centramos en datos más fiables, como son las alcoholurias realizadas con etilglucurónido. Método: estudio de cohorte retrospectivo en pacientes con TUA que acuden a un programa de controles de orina. Con modelos de regresión logística de efectos mixtos, se evalúa la probabilidad de detección positiva de etilglucurónido según las principales características clínicas de los pacientes y el momento de análisis (codificado como antes o después de la implementación del confinamiento domiciliario en España). Resultados: Un total de 362 pacientes proporcionaron 2040 muestras de orina (1295 antes del confinamiento, 745 durante el confinamiento). La edad media de los participantes fue de 52,0 años (DE 12,6) y el 69,2% eran hombres. De todos los pacientes, al 43% se les realizó la prueba de detección para otras dorgas, siendo el 22% de dichos análisis positivos. Después de ajustar para todas las covariables, la probabilidades de detección positiva de etilglucurónido después del confinamiento se duplicó (OR = 1,99, IC del 95%: 1,20 a 3,33, p = 0,008). Otras covariables significativas fueron la positividad a otras drogas(OR = 10,79; IC del 95% 4,60 a 26,97) y la duración del tratamiento (OR = 0,59; IC del 95%: 0,47 a 0,74). Conclusiones: Nuestros datos sugieren la existencia de una asociación entre el confinamiento por COVID-19 y el aumento del consumo de alcohol en pacientes con TUA. Eso significa que los sistemas de atención a las adicciones tienen ante sí importantes desafíos. A la luz de estos hallazgos, sigue siendo esencial evaluar prospectivamente cómo evoluciona esta población y cómo los sistemas de salud responden a sus crecientes necesidades.
Spatial Accessibility in Urban Regeneration Areas: A Population-Weighted Method Assessing the Social Amenity Provision
Authors: Gutting Robin , Gerhold Maria , Rößler Stefanie
Published: November 2021

Principles of social sustainability serve to guide urban regeneration programmes around the world. Increasingly, the upholding of these principles is subject to qualified evaluation and monitoring. One of the cornerstones of social sustainability is access to basic services. This is also a strategic and operational objective in urban regeneration measures. While indicator-based evaluations of accessibility do exist, hitherto they have tended to apply descriptive statistics or density parameters only. Therefore, there is a need for small-scale, regularly updated information on accessibility, such as the nearest facility based on street networks and population density. This deficit can often be attributed to the complex methodological requirements. To meet this need, our article presents a method for determining the spatial accessibility of basic services with low data requirements. Accessibility is measured in walking time and linked to the local population distribution. More specifically, GIS tools in connection with land survey data are used to estimate the number of inhabitants per building; the walking time needed to reach four types of social amenity along the street network is then determined for each building; finally, a population-weighted accessibility index is derived and mapped in a 50-m grid. To test this method, we investigated four urban regeneration areas in Dresden, Germany. The results show that with freely available geodata, it is possible to identify neighbourhoods and buildings with both high population densities and poor accessibility to basic services. Corresponding maps can be used to monitor urban regeneration measures or form a basis for further action.
Digital Urban Regeneration and Its Impact on Urban Renewal Processes and Development
Authors: Shach-Pinsly Dalit
Published: November 2021

Urban renewal is one of the main motivations of city regeneration. Urban renewal strategies mainly relate to demolishing old buildings and redeveloping new buildings instead, improving buildings and deteriorated areas, infilling new buildings within existing urban fabric, integrating new communities into old and rolling-down areas, and so on. In parallel to this situation, the modern world is in the wake of the 4th Industrial Revolution, which is characterized by a merger of physical and digital spaces and is consequently affecting cities and their quality of life. Therefore, urban regeneration must take into consideration these digital innovations and harness the emerging technological changes into new development of urban renewal processes and decision-making approaches. This editorial introduces the topic of digital urban regeneration, by discussing possible methodologies and decision-making approaches and presents the thematic issue on “embedding digital technologies into urban renewal processes and development.”
Future Guanabara Bay Clean-up: Rio de Janeiro’s Hillslope Favelas Ought to Be its Amicable Pinnacles
Authors: Serpa Nilo , Finkl Charles , Cathcart Richard Brook
Published: November 2021

Abstract: This article brings a social discussion about the surroundings of Guanabara Bay, showing that there are technological instruments capable of promoting citizenship and quality of life for the inhabitants of the slum areas. The work is part of the collection of published studies on the Guanabara Bay edited by the electronic journal CALIBRE, integrating a fundamental legacy for future projects in urban ecology.

Key words: favelas, escalators, Guanabara Bay, Macro-Imagineering, asfaltos, favelados.

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Resumo: O presente artigo traz uma discussão social acerca do entorno da Baía de Guanabara, mostrando que há instrumentos tecnológicos capazes de promover cidadania e qualidade de vida para os habitantes das áreas favelizadas. O trabalho se insere na coleção de estudos sobre a Baía de Guanabara publicados no periódico eletrônico CALIBRE, integrando legado fundamental para futuros projetos em ecologia urbana.

Palavras-chave: favelas, escalators, Baía de Guanabara, Macro-Imagineering, asfaltos, favelados.
CONTENT-AND-LANGUAGE INTEGRATED LEARNING AND TEACHING SCIENTIFIC UKRAINIAN TO 10TH-GRADE STUDENTS OF SECONDARY SCHOOL MAJORING IN NATURE AND MATHEMATICS
Authors: Liubashenko Olesia , Manakova Lesia
Published: November 2021

Background. More and more secondary school students in Ukraine and Europe are opting nowadays to
stream for Nature and Mathematics, which is preconditioned by the increased demand for the professionals in
these areas. In this context, Scientific Ukrainian could be packaged into content learning of a range of science disciplines such as Physics, Mathematics, Chemistry, and others if the appropriate CLIL framework is provided both
for contact and distant learning and teaching. As the researchers claim (D.Koyl & D.Marsh), it is the development of speech operations and actions that affects knowledge and skills accumulation on the content level.
Purpose: The purpose of the article is to revisit the instructional capacities of Scientific Ukrainian based on the syllabi and textbooks for the 10th-grade secondary school students majoring in nature and mathematics. The aim is to ground the dual focus on Scientific Ukrainian and content learning in upper- secondary school.
Results and Discussion: Our theoretical speculations have led the authors to the conclusion that the language component of learning and teaching Scientific Ukrainian to 10th grade students should involve lexicography and working with dictionaries, lexicology and mastering the terminology, text search in media resources and its analysis, syntax of the scientific language and scientific text production. According to our observations, most Ukrainian 10thgrade secondary school students majoring in nature and mathematics are keen to master scientific Ukrainian for
future careers related to the fields of Physics, Chemistry, Biology and Mathematics. The distant CLIL instruction was carried out with the involvement of platforms and tools such as GoogleDocs, Zoom, Padlet, Prezi, Kahoot, Quizlet.
The empirical part of the study, with 26 10th- grade students and their teacher of Ukrainian participating, has clearly demonstrated the advantages of CLIL in enhancing both content learning and language competence. Despite positive results observed, more research efforts should be channeled to the development of the criteria to assess
every content component of Scientific Ukrainian as well as to enhancing cooperation between content and language teachers to create opportunities for using the new language resources by students in curriculum planning.
New approach to pre-natal preparation based on biofeedback use
Authors: Osepashvili Maka N. , Ailamazyan Eduard K. , Abramchenko Valery V. , Spivak Dmitriy L.
Published: November 2021

Institute for the human brain RAS, Saint- Petersburg, Russia (head of laboratory of thought and consciousness academician N.P. Bekhtereva).

The authors propose a program of pre-natal psycho physiologic preparation that is based on non-medicine biofeedback (BFB) method. The method is physiologic as it is based on activization of reserve possibilities of the organism.

The objective of the preparation is to assist in good progress of pregnancy and delivery and in good development of a fetus.

The essence of the method is that a patient is trained in controlling and changing the trend of disordered physiologic function that influences the patient's condition and the progress of pregnancy (respiration, muscle and vascular tonus, psycho emotional condition).

The principle procedures are as follows:

Training in controlling the cardio-respiratory system with the help of RSA-BFB (biofeedback for respiratory sinus arrhythmia).

Correction of the patient's psycho emotional condition with the help of EEG-BFB.

Training in controlling muscle activity with the help of EMG-BFB.

After the course of pre-natal psycho physiologic preparation not only do the expectant mothers gain a general impression of how the delivery goes on, but they also acquire the practical habits to behave during delivery. It is very good that they feel less fear of delivery, less fear for their infant's life and health in comparison with the control group. The authors' studies have shown that the frequency of premature and delayed births is decreased by more than 1,5 times in comparison with the control group, usage of medicinal stimulation of delivery, analgesic and spasmolitic medicaments decreased, the quantity of injuries of soft birth throes decreased two times.
Hygienic characteristic of actual nourishment of small peoples of the far north
Authors: Raengulov B. M. , Istomin A. V. , Mikhailov I. G. , Shushkova T. S.
Published: November 2021

The actual nourishment of the representatives of small peoples of the Far North: Nenets, Khanty, Komi as well as some indices of the functional state of central nervous and cardiovascular systems of the organism are studied. The revealed peculiarities of food status are the bases for development of hygienic recommendations on nourishment optimization and population health improvement.
Experience in the application of low-frequency magnetic stimulation in the complex treatment of multiple sclerosis patients
Authors: Rakhmatullin M. Sh. , Anufriev A. Yu.
Published: November 2021

Multiple sclerosis (MS) is the most common chronic disease, leading to early and profound disability, mainly in persons of young age. The morphological substrate of the disease is the death of myelin (demyelination) in the white matter of the spinal cord and brain. Recently, there has been a trend toward increased morbidity and complications.
Role of studying the pathogenesis of retinopathy of prematurity in optimizing disease screening
Authors: Katargina Lyudmila A. , Chesnokova Natal’ya B. , Balatskaya Natal’ya V. , Osipova Natal’ya Anatolievna , Panova Anna Yurievna
Published: November 2021

Background: The efficiency of treatment and prevention of retinopathy of prematurity (ROP) has improved. In addition, the development of a disease screening system to reduce the incidence of disability resulting from this pathology is important.
Aim: This study aimed to determine new laboratory criteria for screening and predicting the ROP course through in-depth investigation of the molecules participating in the pathogenesis of ROP.
Material and methods: A comprehensive clinical and experimental study was performed to assess the local and systemic levels of 49 cytokines with various biological effects, four monoamines, and angiotensin-II (AT-II) at different stages of the pathological process. In the clinical analysis, 165 preterm infants at risk of ROP development were examined. For the experimental part, the disease course of 145 Wistar infant rats in the developed model of experimental ROP was analyzed.
Results: Among cytokines, the seven most promising potential laboratory markers of ROP development and adverse course were as follows: MCP1 95 pg/mL, IGF-II 140 pg/mL, TGFbeta1 18000 pg/mL, and IGF-I 24 pg/mL in the blood serum of preterm infants before the first signs of ROP and VEGF-A 108 pg/mL, TGF-beta2 100 pg/mL, and PDGF-BB 1800 pg/mL at ROP manifestation. Among monoamines, serotonin (17.0 pg/mL) and L-DOPA indicated their prognostic value in the clinical and experimental settings. Moreover, a possible prognostic role of AT-II was found.
Conclusion: In this study, methods to improve the ROP screening system are outlined, but further work is necessary to assess the possibility of implementing the results in clinical practice
The efficiency of congenital cataract management in children
Authors: Afanasyeva Daria S. , Zhadan Vasilii A.
Published: November 2021

Aim: This study aimed to analyze the results of congenital cataract treatment in children who underwent surgery in VP Vyhodcev Eye Hospital from 2015 to 2019 and to compare these data with global results.
Material and methods: A retrospective analysis of electronic outpatient medical records of children who underwent surgery for congenital cataract during the period from 2015 to 2019 included the following parameters: age at the first admission to the Eye Hospital, delay between the first admission and cataract surgery, age at surgery, best corrected visual acuity at the end of follow-up, and presence of any eye comorbidities. To compare the obtained data with the results of similar studies worldwide, articles on this topic published during the past 5 years were searched.
Results: This retrospective study analyzed 71 electronic outpatient medical records of children with congenital cataract (96 eyes). The age at the first admission was 33.5 [60.081.5] months. The best corrected visual acuity before surgery was 0.2 [0.10.4]. The delay between the first admission and cataract surgery was 5.0 [2.512.0] months; thus, children underwent surgery for congenital cataract at age 51 [14.594.5] months. In all patients, lens aspiration with intraocular lens implantation resulted in significant improvement of visual acuity to 0.4 [0.10.9]. The comparative analysis revealed a trend for earlier recognition and surgical treatment of congenital cataract in European countries, while a significant delay before surgery and worse visual outcomes are common in developing countries.
Conclusion: The current state of ophthalmological care for children with congenital cataract in Russia allows achieving good visual outcomes comparable with published results in Europe. Nonetheless, further studies are required to determine reasons for later recognition and surgery of congenital cataract in children
Special Needs Insurance: More Stability for a Growing Family's Budget
Authors: Morel David
Published: November 2021

Objective.—

To propose an insurance product called special needs insurance. The insurance will pay parents a lump sum up to $100,000 if they have a child that is born with or develops a special needs condition such as Down syndrome, cerebral palsy or autism.

Background.—

Raising a child is expensive; raising a child with a special need can be hundreds of thousands of dollars more expensive. These additional costs include direct costs that are not covered by health insurance and indirect costs such as the loss of earnings when a working parent must tend to a special needs child.

Method.—

We analyze a gamut of birth and early childhood disabilities, both physical and cognitive, from the medico-actuarial perspective. We describe each condition using relevant medical literature and calculate prevalence rates from epidemiological studies (appendix A1-A15). After accounting for multiple births, we develop a final premium.

Results.—

We find that physical impairments are sufficiently well understood to guarantee a fixed payout, whereas cognitive impairments such as autism are less understood, and so for these we propose a cognitive fund that does not guarantee a fixed payout. We find that an average single premium of $4,600 allows the insurer to profitably pay out the proposed benefits.

Conclusions.—

Raising a special needs child can put a significant strain on the affected family's budget. We propose an insurance product that provides relief through a large lump sum payout. Although no new insurance product can be guaranteed success, our analysis of this product gives an interested insurer reasonable justification to take on this new risk.
Utilizing an Arduino-Based Accelerometer in Civil Engineering Applications in Undergraduate Education
Authors: Komec Mutlu Ahu , Tugsal Ulgen Mert , Dindar Ahmet Anil
Published: November 2021

One of the most important issues in civil engineering undergraduate education is response analysis of structures for earthquake-resistant design. Precautions that should be taken against seismic hazards not only include the design of earthquake-safe buildings but also monitoring the strength and dynamic characteristics of structures. Because this is an important topic in theoretical aspects of civil engineering education at the undergraduate level, it is essential to have opportunities to perform practices so students can better understand lectures. In the Gebze Technical University (GTU) Civil Engineering Department, we guide our undergraduate students to graduate as competent engineers who use practice tools. For this purpose, we designed an Arduino-based accelerometer device and its software toolkit, which records and visualizes structural vibration data in the process of learning the best practices of seismic safety. The device contains Arduino UNO board ADXL345 MEMS (microelectromechanical systems) Accelerometer and microSD card module. Both Arduino and Python open-source programming languages were implemented in the device. We have produced a total number of 15 accelerometers (named the ACCE_edu-Arduino based accelerometer for Civil Engineering education) integrating these cards and sensors that are widely used for vibration measurement and interpretation to record vibration data. Within the scope of “Python programming” lectures in the GTU undergraduate program, these toolkits will be used to obtain data that would be recorded, stored, visualized, and filtered using Python programming language, which provides a practical application in data processing.
Benchmarking Automated Rayleigh-Wave Arrival Angle Measurements for USArray Seismograms
Authors: Frazer William D. , Doran Adrian K. , Laske Gabi
Published: November 2021

Surface-wave arrival angles are an important secondary set of observables to constrain Earth’s 3D structure. These data have also been used to refine information on the alignments of horizontal seismometer components with the geographic coordinate system. In the past, particle motion has been inspected and analyzed on single three-component seismograms, one at a time. But the advent of large, dense seismic networks has made this approach tedious and impractical. Automated toolboxes are now routinely used for datasets in which station operators cannot determine the orientation of a seismometer upon deployment, such as conventional free-fall ocean bottom seismometers. In a previous paper, we demonstrated that our automated Python-based toolbox Doran–Laske-Orientation-Python compares favorably with traditional approaches to determine instrument orientations. But an open question has been whether the technique also provides individual high-quality measurements for an internally consistent dataset to be used for structural imaging. For this feasibility study, we compared long-period Rayleigh-wave arrival angles at frequencies between 10 and 25 mHz for 10 earthquakes during the first half of 2009 that were recorded at the USArray Transportable Array—a component of the EarthScope program. After vigorous data vetting, we obtained a high-quality dataset that compares favorably with an arrival angle database compiled using our traditional interactive screen approach, particularly at frequencies 20 mHz and above. On the other hand, the presence of strong Love waves may hamper the automated measurement process as currently implemented.
La Universidad Sénior: derribando barreras y estereotipos en tiempos de COVID
Authors: Ares-Pernas Ana , Iglesias Antelo Susana , García-Sánchez Matilde
Published: November 2021

En este trabajo se recogen las acciones llevadas a cabo durante el confinamiento del curso 2019/2020 y en el curso 2020/2021 para adaptar la docencia de la Universidad Sénior a la modalidad online. Durante los primeros meses el reto fue tratar de garantizar la continuidad de la actividad formativa, y para ello se diseñó a través de wordpress una herramienta abierta adaptada a las necesidades y circunstancias del alumnado mayor de 50 años. En el curso 2020/2021 se creó el Programa de Formación Específico “Actualidad, Ciencia, Salud y Vida”, de carácter semipresencial, en el que se combinaron sesiones online con sesiones presenciales en grupos reducidos. Las sesiones de formación, la atención personalizada y todo el material de apoyo elaborado desde el equipo de la Universidad Sénior, como infografías y videotutoriales, ayudaron al alumnado a alcanzar las competencias digitales que les permitieron seguir la docencia online. De los testimonios recogidos y de la experiencia vivida durante el curso se puede concluir que la pandemia fue una oportunidad para que nuestro alumnado derribase la barrera tecnológica e incorporase las nuevas tecnologías en su vida cotidiana, rompiendo de esta manera muchos de los estereotipos ligados al envejecimiento.
Mentoría en la Universidad: formación de las figuras implicadas
Authors: Rodicio-García María-Luisa , Ríos-de-Deus María-Paula , Mosquera-González María-José , Rego-Agraso Laura
Published: November 2021

En este trabajo se presenta una propuesta formativa transversal en formato MOOC (Massive Online Open Courses). El principal objetivo fue diseñar una herramienta de formación en mentoría dirigida, fundamentalmente, a profesorado y alumnado. Para su elaboración se contó con el apoyo técnico del Centro Universitario de Formación e Innovación Educativa (CUFIE), desde donde se puso en marcha la II Convocatoria para la elaboración de MOOC de la Universidade da Coruña 2018/19. El curso “Mentoría en la Universidad. Formación de las Figuras Implicadas (MUFFIM)”, se elaboró desde octubre de 2019 hasta abril de 2021. Está programado para realizar en cuatro semanas y tiene una duración total de 20 horas. Consta de cuatro módulos que desarrollan contenidos relativos a cómo se sitúa la mentoría en el escenario actual de la universidad, su conceptualización y el desarrollo de algunas competencias necesarias para asumir algún rol dentro de un proceso de mentoría. El número de inscritos ha sido de 440 personas, de las cuales la mayoría son docentes (40,2%) y estudiantes universitarios (23,47%), de 19 países, entre los que destacan los Iberoamericanos, Francia, Alemania, Portugal, Rusia y Andorra. Los principales resultados muestran la gran acogida por parte de los/as participantes que consideran importante trabajar estas temáticas en el contexto universitario.
Os seminarios PAT da Facultade de Economía e Empresa na Nova Normalidade Académica
Authors: Rodríguez-Gulías María Jesús
Published: November 2021

O Plan de Acción Titorial (PAT) da Facultade de Economía e Empresa (FEE) da Universidade da Coruña (UDC) tivo que enfrontarse no curso 2020-2021, como o resto da Universidade, á Nova Normalidade Académica (NNA) derivada da crise sanitaria provocada polo virus SARS-CoV-2 que deu lugar á enfermidade COVID-19. Un dos aspectos nos que o PAT da FEE debeu adaptarse á NNA foi no relativo ao seu Plan de Formación coordinado dende o Servizo de Formación do PAT e no que se encadran os Seminarios PAT da FEE, cursos breves de formación complementaria, transversal, opcional e gratuíta. Coa intención de manter en funcionamento o Servizo de Formación do PAT e continuar ofertando os Seminarios PAT da FEE, decidiuse facer un movemento cara a un sistema de seminarios PAT virtuais e síncronos a través da plataforma MS TEAMS, así como a unha coordinación e xestión dos mesmos tamén maioritariamente telemática. Os resultados deste necesario cambio de sistema foron positivos e, non so se mantiveron os seminarios que tradicionalmente se viñan impartindo, se non que incluso se incrementou a oferta dos mesmos, logrando cifras de asistencia notables.
Unha experiencia de adaptación metodolóxica á docencia virtual e as súas implicacións no seguimento por parte do alumnado
Authors: Soneira Carlos
Published: November 2021

Neste traballo expóñense os cambios metodolóxicos, incluíndo os relativos á avaliación e ás titorías levados a cabo na materia Educación Matemática 1, de 1º do grao en Educación Primaria para adaptar a docencia á modalidade virtual. Para as sesións asíncronas, graváronse vídeos explicativos sobre contidos teóricos aos que o alumnado podía acceder con antelación. As sesións síncronas dedicáronse principalmente a ilustrar a posta en práctica dos contidos teóricos expostos nos vídeos. Nelas os estudantes empregaron os recursos que ofrece Teams para se organizar en pequenos grupos dentro do grupo xeral, o que facilitou a interacción co docente. A avaliación foi continua, con varias probas síncronas individuais a través de Moodle e a realización dun traballo por grupos. As titorías realizáronse vía Teams e cobraron maior peso relativo respecto a cursos anteriores, con docencia presencial. O seguimento das distintas sesións foi, en termos xerais, sostido ao longo do cuadrimestre, e non houbo incidencias importantes na realización das probas on-line nin no funcionamento dos pequenos grupos. Porén, algúns fenómenos observados durante as sesións síncronas suxiren posíbeis anomalías no xeito de atender á sesión. Os resultados da avaliación foron máis positivos ca nas edicións presenciais da materia.
Bio-assembling and Bioprinting for Engineering Microvessels from the Bottom Up
Authors: Liu Xiaoming , Yue Tao , Kojima Masaru , Huang Qiang , Arai Tatsuo
Published: November 2021

Blood vessels are essential in transporting nutrients, oxygen, metabolic wastes, and maintaining the homeostasis of the whole human body. Mass of engineered microvessels is required to deliver nutrients to the cells included in the constructed large three-dimensional (3D) functional tissues by diffusion. It is a formidable challenge to regenerate microvessels and build a microvascular network, mimicking the cellular viabilities and activities in the engineered organs with traditional or existing manufacturing techniques. Modular tissue engineering adopting the “bottom-up” approach builds one-dimensional (1D) or two-dimensional (2D) modular tissues in micro scale first and then uses these modules as building blocks to generate large tissues and organs with complex but indispensable microstructural features. Building the microvascular network utilizing this approach could be appropriate and adequate. In this review, we introduced existing methods using the “bottom-up” concept developed to fabricate microvessels including bio-assembling powered by different micromanipulation techniques and bioprinting utilizing varied solidification mechanisms. We compared and discussed the features of the artificial microvessels engineered by these two strategies from multiple aspects. Regarding the future development of engineering the microvessels from the bottom up, potential directions were also concluded.
Elastic and Stretchable Double Network Hydrogel as Printable Ink for High-Resolution Fabrication of Ionic Skin
Authors: Chen Kaiwen , Ying Qiwei , Hao Xingxing , Sun Kai , Wang Huanan
Published: November 2021

A hydrogel that combines both printability and adaptability, high elasticity, and stretchability can provide ideal mechanical properties, and also render complex and accurate construction for ionic skin. However, it is extremely challenging. Here, we propose a colloidal-based double-network (DN) hydrogel as printable inks for high-precision fabrication of ionic skins. Particularly, polyacrylamide (PAAm), as the covalent network that can maintain the long-term material integrity, was combined with gelatin colloidal network to improve the injectability and printability of the resulting DN hydrogels. The DN design cooperatively provides the hydrogels with higher toughness values and deformability than what single colloidal or PAAm network can achieve. Further design of ionic skin based on capacitor microarray was demonstrated to serve as a sensitive and stable capacitor that can respond to external stimuli, thereby allowing to sense the body movements such as finger bending, laugh, and wrist pulse by translating mechanical changes into electric signals. Therefore, this study provides a novel strategy for the design and preparation of high-resolution ionic skins as the wearable sensor.