bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengelolaan mandiri penyakit kronik degeneratif di Posyandu Lansia, Desa Wonorejo, Maron, Probolinggo
Authors: Nur Hamim  , Yulia Rahmawati
Published: July 2024

Degenerative chronic diseases, especially diabetes mellitus and hypertension, are a major concern in Indonesia, especially in East Java Province. In Probolinggo Regency, especially in Wonorejo Village, Maron, the number of cases of chronic degenerative diseases among the elderly is very high. To overcome this problem, community service activities were carried out by implementing research in the field gerontiki nursing and Posyandu management. Activity methods include lectures, healthy food demonstrations, blood pressure measurements, and simulations on managing Posyandu for the elderly. The results include increasing the knowledge and skills of Posyandu cadres regarding chronic degenerative diseases creating new cadres. Success factors include socialization, personal approach, and student involvement. Even though there are differences in participants' assumptions, initiatives to strengthen old cadres and create new cadres are important. Even though the simulation took a long time, the participants remained enthusiastic. This activity succeeded in increasing the role of elderly Posyandu cadres in managing chronic degenerative diseases, providing a positive impact on the health of the elderly in Wonorejo Village, Maron, and perhaps also the surrounding area.
Meningkatkan partisipasi anggota kelompok wanita tani dalam pemanfaatan lahan pekarangan di Desa Karangrejo
Authors: Dhony Hermawan Saputra
Published: July 2024

Home garden farming is a significant component of initiatives in many areas to enhance family well-being. The primary issue at hand, though, is the low usage of yard space. The purpose of this service was to address this issue by enhancing the involvement of members of the Women Farmer Group (KWT) in the utilization of yard land and its influence on the financial growth of families. A participatory strategy is employed, involving training, mentorship, and granting access to sufficient resources. According to the service's statistics, KWT members are using yard land at a significantly higher rate, which benefits both family income and agricultural productivity. In addition, the involvement of KWT members also helps to raise.
Aplikasi Deteksi Wajah Dan E-Learning Berbasis Pengenalan Untuk Otentikasi Mahasiswa
Authors: Yunus Mughaffir , Riyadi Syamsu
Published: July 2024

Otentikasi siswa dilakukan menggunakan Image Processing. Proses Otentikasi sangat mengandalkan Deteksi Wajah dan Pengenalan Wajah pada saat kegiatan pembelajaran. Penelitian ini dilakukan di Universitas Muhammadiyah Parepare Fakultas Teknik Informatika Kelas F yang dapat memberikan sumber data dan pengetahuan tentang sistem yang diteliti, kemudian mencocokkannya dengan kemungkinan-kemungkinan yang terjadi dalam upaya penyelesaian masalah Analisis dan perancangan sistem adalah tahap pengumpulan data dan kebutuhan informasi kemudian mengolahnya sehingga persyaratan yang harus dipenuhi sistem yang akan dibangun. Jenis data yang dikumpulkan pada saat proses pengumpulan data berupa data sekunder. Penerapan aplikasi ini dilakukan setelah proses registrasi mandiri pengguna selesai. Untuk menjalankan aplikasi ini, maka dibutuhkan sebuah perangkat smartphone berbasis android. Jadi setiap perangkat yang menginstal atau menggunakan aplikasi ini akan memiliki database tersendiri di smartphone lokal atau Android. Berdasarkan hasil pengujian aplikasi pendeteksi wajah didapatkan bahwa jarak terdekat yang dapat mendeteksi wajah adalah jarak 20 cm dan jarak terjauh pada 100 cm.
Simulator Web Exchange Cryptocurrency Menggunakan Metode Rest Api
Authors: Alif Utama Fiqri , Hamra Hamra
Published: July 2024

Cryptocurrency telah menjadi fenomena global yang mendominasi pasar keuangan dalam beberapa tahun terakhir. Pertumbuhan signifikan dalam perdagangan Cryptocurrency menimbulkan permintaan yang tinggi akan platform pertukaran (exchange) yang handal. Penelitian ini dibuat bertujuan untuk memberikan pengguna pemahaman yang lebih baik tentang operasi dan proses yang terlibat dalam pertukaran kripto melalui antarmuka web yang mudah digunakan. Penelitian ini dikembangkan dengan menggunakan metode REST API dan dikembangkan sebagai aplikasi website menggunakan Bahasa pemrograman HTML, CSS dan Javascript dan  bahasa  pemrograman  PHP untuk bagian server-side. Penelitian ini menggunakan data yang diambil dari Application Programming Interface (API) Cryptocompare sebagai pusat data-data kripto yang ada di dalam aplikasi  seperti  nama  koin,  harga  koin  dan  juga  perkembangan koin  tersebut  dalam  suatu  waktu tertentu. Berdasarkan pengujian sistem secara kesuluruhan aplikasi simulator web exchange cryptocurrency ini dapat digunakan sebagai bentuk media pembelajaran yang baik.
(C4H9)3CH3NBF4–Сnanodiamonds
Authors: Stebnitsky I. A. , Uvarov N. F. , Mateyshina Yu. G.
Published: July 2024

The paper presents the results of studies of the structural, thermal and transport properties of solid composite electrolytes (1 – x)(C4H9)3CH3NBF4 – xCND (where CND are nanosized diamonds, 0 ≤ x 1, x is the mole fraction). It has been shown by the Powley method that the crystal structure of the low-temperature phase (C4H9)3CH3NBF4 is described by the space symmetry group P42/ncm. It was found that the addition of a nanodiamond inert additive leads to an increase in the electrical conductivity of the composite electrolyte by 4 orders of magnitude up to a value of 1.3∙10–3 S/cm at 145°C at x = 0.98. The theoretical dependences describe well the experimental data in the concentration range 0 ≤ x ≤ 0.99 at temperatures of 84 and 127 оC.
Investigation of the stability of microtube membranes based on Ba0.5Sr0.5Co0.8 – xFe0.2MoxO3 – δ oxides
Authors: Shubnikova E. V. , Bragina O. A. , Nemudry A. P.
Published: July 2024

The present article is devoted to the study of the stability of microtubular membranes based on Ba0.5Sr0.5Co0.8 – xFe0.2MoxO3 – δ oxides obtained by the phase inversion method. The work shows that MT membranes of the composition BSCFMx exhibit long-term stability and resistance to thermal cycling in an air/helium gradient. The maximum oxygen fluxes were achieved using an MT membrane of composition Ba0.5Sr0.5Co0.75Fe0.2Mo0.05O3 – δ (JO2 =7.6 ml*cm-2min-1 at Т=850 oС and pO2.1 = 0.21 atm). In this work, a detailed equilibrium phase diagram for the BSCFM5 oxide has been obtained. The absence of unwanted phase transitions has been demonstrated.
Anxious and melancholic depression are followed by differently directed serum albumin conformation
Authors: Uzbekov M. G. , Smolina N. V. , Syrejshchikova T. I. , Maximova N. M. , Shikhov S. N. , Dobretsov G. E. , Brilliantova V. V. , Krjukov V. V.
Published: July 2024

The aim of the study was investigation of the peculiarities of the conformational changes of serum albumin in patients with anxious and melancholic depression. Albumin conformation was measured by the method of the subnanosecond laser time resolved fluorescence spectroscopy. Anxious depression was followed with the significant decrease of the values of the three amplitudes on the serum albumin in comparison with controls. In the melancholic depression the values of all three amplitudes on serum albumin molecules were significantly elevated in comparison with controls. These results are clearly indicated that anxious and melancholic depression are followed by differently directed changes in serum albumin conformation.
Ciliary neurotrophic factor as a potential biomarker of cerebral pathologies
Authors: Gudkova A. A.
Published: July 2024

Ciliary neurotrophic factor (CNTF) is a pluripotent neurotrophic factor with high neuroprotective potential, a neurocytokine that has demonstrated potential in the therapy of neurodegenerative, psychiatric and metabolic diseases. Preclinical data support the general concept of its potential neuroprotective and trophic effects, and recent clinical data support the potential role of CNTF in the treatment of neurodegeneration and obesity. A number of data indicate the involvement of CNTF in stress reactivity and the pathogenesis of affective disorders. Data from studies of CNTF levels in invasive (blood) and non-invasive (tears) human biomaterials suggest the possibility of its use as a biomarker for certain brain diseases, although more research is needed to confirm this.
Localization of the stem cells exosomes in the brain and in the cultured mouse brain cells
Authors: Ratushnyak M. G. , Rodina A. V. , Shaposhnikova D. A. , Moskaleva E. Yu.
Published: July 2024

The possibility of transferring exosomes of neural (NSC) and mesenchymal (MSC) mouse stem cells labeled with the fluorescent dye PKH26 into the cerebral cortex and hippocampus after their intranasal administration to mice, and the accumulation and localization of exosomes in cultured brain cells of various types, and also the effect of exosomes of NSCs and MSCs on the parameters of the cell cycle and the level of apoptosis of cultured NSCs after irradiation at a dose of 4 Gy. The accumulation of exosomes obtained from the culture medium of NSCs and MSCs from the adipose tissue of C57BL/6 mice was shown both in the hippocampus and in the cerebral cortex after their intranasal administration to syngeneic mice. Exosomes were found predominantly in the perinuclear region of brain cells. When culturing NSCs and differentiated from NSCs neurons and astrocytes, exosomes accumulate more intensively in astrocytes and are also localized in the perinuclear region of cells, and in astrocytes also in the cytoplasm. Exosomes accumulated most intensively in astrocytes. When studying the effect of stem cell exosomes on the cell cycle of irradiated NSCs, it was shown that the cultivation of NSCs irradiated at a dose of 4 Gy in the presence of exosomes of both NSCs and mouse MSCs does not lead to the restoration of cell cycle parameters, but provides a decrease the number of apoptotic cells in 24 h after exposure.
Patterns of changes in certain neurospecific proteins in patients with post-contact period chronic mercury intoxication
Authors: Bodienkova G. M. , Boklazhenko E. V.
Published: July 2024

The aim of the study was to identify patterns of change in certain neurospecific proteins (BDNF, S100β, MBP) in the serum of patients with chronic mercury intoxication (CMI) after stopping exposure to the toxicant. In clinical conditions, men with an established diagnosis of chronic mercury intoxication were examined in a distant period after isolation from a toxicant in chemical production. Serum concentrations of neurospecific proteins (BDNF, S100β, MBP) were determined by solid-phase enzyme-linked immunosorbent assay using a commercial test-systems of ChemiKine (USA), CanAg (Sweden) and AnshLabs (США) respectively. The obtained results indicate and confirm the progressionality of the disease process in the distant, post-exposure period of chronic mercury intoxication, which corresponds to the clinic of the manifestation of the disease. Elevated serum concentrations of BDNF, S100β protein, and MBP were reported in patients with CMI after 5 years of exposure to the toxicant. Long-lasting high levels of neurotrophic proteins may reflect the course of neurodestructive processes occurring in the nervous tissue and the progression of the disease. BDNF deficiency in CMI individuals examined in a linked sample at 8 years post-exposure may be indicative of attenuation of neurogenesis. Further studies will contribute to a more accurate definition and understanding of the use of serum concentrations of BDNF, S100β protein, MBP as markers of pathological process activity and a specific target for effective treatment.
MENINGKATKAN AKTIVITAS DAN HASIL BELAJAR EKONOMI MENGGUNAKAN VIDEO PEMBELAJARAN PADA PEMBELAJARAN DARING SISWA KELAS XI IPS 3 SMA NEGERI 1 SITIUNG TAHUN PELAJARAN 2020 / 2021
Authors: Sulastri, A.M Sulastri, A.M
Published: July 2024

Media Video pembelajaran  dapat di implementasikan dalam kelas daring untuk meningkatkan aktivitas dan hasil belajar peserta didik khususnya dalam mata pelajaran ekonomi, khususnya materi  perdagangan international dan kerjasama ekonomi international. Dengan media video Pembelajaran ini dapat digunakan sebagai salah satu solusi dan sebagai alat bantu untuk memudahkan proses pembelajaran daring dimasa pandemi covid 19 secara keseluruhan, juga merobah asumsi siswa yang mengatakan pembelajaran daring hanya kebijakan yang tidak serius dari pemerintah
PENINGKATAN HASIL BELAJAR MATEMATIKA SISWA MELALUI MODEL PEMBELAJARAN DISCOVERY LEARNING DI SMKN 3 PARIAMAN
Authors: Nailil Fiza Prihartini Nofita Eka Pasca Surya Bayu
Published: July 2024

Penelitian ini bertujuan untuk mendeskripsikan Peningkatan Hasil Belajar Matematika Siswa melalui Model Pembelajaran Discovery Learning di Kelas X Rekayasa Perangkat Lunak SMKN 3 Pariaman. Rumusan masalahnya adalah “Apakah melalui Model Pembelajaran Discovery Learning dapat meningkatkan hasil belajar matematika siswa kelas X Rekayasa Perangkat Lunak di SMKN 3 Pariaman. Penelitian ini merupakan penelitian tindakan kelas yaitu guru berperan langsung dalam proses pembelajaran. Subjek dalam penelitian ini Kelas X Rekayasa Perangkat Lunak SMKN 3 Pariaman yang berjumlah 32 orang dan objek penelitian ini adalah peningkatan hasil belajar matematika siswa melalui model pembelajaran Discovery Learning. Instrumen yang digunakan adalah tes berbentuk essay. Tes digunakan untuk mengetahui hasil belajar matematika siswa. Berdasarkan analisis data hasil belajar matematika siswa pada siklus I adalah 27 siswa yang tuntas (84,38%) dan yang belum tuntas 5 siswa (15,62%), sedangkan pada siklus II yang tuntas menjadi 29 siswa (90,62%) dan yang belum tuntas 3 siswa (9,38%) dengan peningkatan nilai Rata-rata kelas siklus I=70,93 sedangkan pada siklus II nilai rata-rata kelas=76,72 yang mengalami peningkatan secara signifikan. Hasil analisis data yang diperoleh dapat disimpulkan bahwa melalui Model Pembelajaran Discovery Learning dapat meningkatkan hasil belajar matematika siswa kelas X Rekayasa Perangkat Lunak di SMKN 3 Pariaman.
MODEL PEMBELAJARAN PROBLEM BASED LEARNING PADA MATERI FUNGSI KUADRAT
Authors: Nofri Leni Rahma Yesya Eka Pasca Surya Bayu
Published: July 2024

Tujuan penulisan ini adalah untuk menggambarkan pelaksanaan pembelajaran menggunakan model pembelajaran Problem Based Learning (PBL) yang dilaksanakan pada materi fungsi kuadrat. Pembelajaran dilaksanakan dengan penelitian deskriptif kualitatif yang menarasikan semua kondisi pelaksanaan pembelajaran. Hasil yang diperoleh dari pelaksanaan model PBL ini menunjukkan adanya peningkatan hasil belajar siswa, peningkatan kemampuan pemecahan masalah dan peningkatan aktifitas siswa dalam pembelajaran. Hal ini dibuktikan dari aktifitas pembelajaran yang kolaboratif dan komunikatif. Siswa berani menyampaikan ide dan berani mempresentasikan di depan kelas serta hangatnya diskusi dua arah yang terjadi selama pembelajaran berlangsung.
PENINGKATAN HASIL BELAJAR BAHASA INGGRIS SISWA MELALUI METODA PEMBELAJARAN PROBLEMS BASED LEARNING DI KELAS VII SMP NEGERI 14 MUKOMUKO
Authors: Mira Amazola Gusmaizal Syandri Fitri Yulianti
Published: July 2024

Penelitian ini bertujuan untuk mendeskripsikan Peningkatan Hasil Belajar Bahasa Inggris Siswa melalui Metoda Pembelajaran Problems Based Learning di Kelas VII SMP 14 Mukomuko. Dalam penelitian ini rumusan masalahnya adalah “Apakah melalui Model Pembelajaran Problems Based Learning dapat meningkatkan hasil belajar Bahasa Inggris siswa Kelas VII SMP 14 Mukomuko. Penelitian ini merupakan penelitian tindakan kelas yaitu guru berperan langsung dalam proses pembelajaran. Subjek dalam penelitian ini Kelas VII SMP 14 Mukomuko yang berjumlah 20 orang dan objek penelitian ini adalah Peningkatan Hasil Belajar Bahasa Inggris Siswa melalui Model Pembelajaran Problems Based Learning. Instrumen yang digunakan dalam penelitian ini adalah tes berbentuk esay. Tes digunakan untuk mengetahui hasil belajar Bahasa Inggris siswa. Berdasarkan analisis data hasil belajar Bahasa Inggris siswa pada siklus I adalah 16 siswa yang tuntas (80 %) dan yang belum tuntas 4 siswa (20 %), sedangkan pada siklus II yang tuntas menjadi 18 siswa (90%) dan yang belum tuntas 2 siswa (10 %), sehingga berdasarkan hasil analisis data yang diperoleh dapat disimpulkan bahwa Melalui Model Pembelajaran Problems Based Learning dapat meningkatkan hasil belajar Bahasa Inggris siswa Kelas VII SMP 14 Mukomuko.
GAYA BAHASA CERAMAH USTAZAH MAMAH DEDEH BERDASARKAN NADA DAN STRUKTUR KALIMAT DALAM ACARA HATI KE HATI BERSAMA MAMAH DEDEH DI ANTV: SUATU KAJIAN PEMBELAJARAN RETORIKA
Authors: Rosmita Ermi
Published: July 2024

Penelitian ini bertujuan untuk (a) mendeskripsikan gaya bahasa ceramah Ustazah Mamah Dedeh berdasarkan nada dalam acara Hati ke Hati Bersama Mamah Dedeh di ANTV dan (b) mendeskripsikan gaya bahasa ceramah Ustazah Mamah Dedeh berdasarkan struktur kalimat dalam acara Hati ke Hati Bersama Mamah Dedeh di ANTV. Jenis penelitian ini adalah penelitian kualitatif dengan menggunakan metode deskriptif. Data yang digunakan dalan penelitian dikumpulkan dengan cara dokumentasi. Teknik analisis data yang digunakan adalah content analysis (analisis isi). Berdasarkan hasil penelitian, disimpulkan a) gaya bahasa berdasarkan nada yang cenderung digunakan dalam ceramah Ustazah Mamah Dedeh adalah gaya bahasa sederhana dan gaya bahasa mulia dan bertenaga; dan (b) gaya bahasa berdasarkan struktur kalimat yang digunakan Ustazah Mamah Dedeh dalam ceramahnya adalah gaya bahasa klimaks, antiklimaks, paralelisme, antitesis, dan repetisi. Dalam hal ini dapat disimpulkan bahwa setiap orang di dalam beretorika memiliki gaya bahasa masing-masing yang menjadi ciri khasnya dalam menyampaikan sesuatu pesan, tidak terkecuali pada seorang pendakwah, seperti Mamah Dedeh
АНАЛІЗ ТЕХНОЛОГІЙ ТА ЕТАПІВ РОЗРОБКИ ІНТЕЛЕКТУАЛЬНИХ ІЄРАРХІЧНИХ АВТОМАТИЗОВАНИХ СИСТЕМ УПРАВЛІННЯ В ІНДУСТРІЯХ 4.0 ТА 5.0
Authors: ПАВЛЮК Олена , МІЩУК Мирослав , МЕДИКОВСЬКИЙ Микола , ЛІТОВСЬКА Олена
Published: July 2024

Проведено порівняльний аналіз технологій та етапів розробки ієрархічних автоматизованих систем управління (ІАСУ) в контексті Індустрії 4.0 та Індустрії 5.0, з акцентом на розподілені системи збору та аналізу інформації і федеративне навчання для промислових підприємств, які використовують мобільні робототехнічні платформи (МРП). Основна мета роботи полягає у виокремленні технологій, інструментів та етапів розробки ІАСУ для забезпечення ефективного переходу до Індустрії 5.0. У дослідженні проаналізовано основні характеристики ІАСУ в Індустрії 4.0 та 5.0, визначено обмеження існуючих технологій Індустрії 5.0, встановлено етапи розробки ІАСУ, наведено приклади їх застосування для моніторингу та оптимізації маршрутів МРП. Описана структура ІАСУ з федеративним навчанням на основі розподіленої системи збору інформації з IoE для оптимізації маршрутів МРП в Індустрії 5.0. Наведено приклади розроблених додатків для збору інформації з сенсорів портативних пристроїв виробничого персоналу.
Перевагами запропонованої структури федеративного навчання в Індустрії 5.0 є можливість підвищення ефективні методів управління промисловими підприємствами, що використовують МРП, їх гнучкості та адаптивності, економія ресурсів, зниження ризиків, покращення управління та моніторингу. Проведено аналіз обмежень існуючих технологій Індустрії 5.0 які дозволяють виявити потенційні ризики та розробити стратегії для їх мінімізації. Це сприяє підвищенню стабільності та надійності виробничих систем. Впровадження інноваційних технологій, що відповідають принципам Індустрії 5.0, сприяє сталому розвитку підприємств, забезпечуючи баланс між економічними, соціальними та екологічними аспектами.
ІНТЕРАКТИВНИЙ МОБІЛЬНИЙ ДОДАТОК ДЛЯ ПІДТРИМКИ ОСІБ ІЗ ПОРУШЕННЯМИ МОВЛЕННЯ
Authors: МЕЛЬНИК Анна , ЛІП’ЯНІНА-ГОНЧАРЕНКО Христина
Published: July 2024

У зв'язку з швидким розвитком технологій і поширенням мобільних пристроїв, використання мобільних додатків у сфері логопедії відкриває нові можливості для вдосконалення методів корекції мовленнєвих порушень у дітей та дорослих. Мобільні додатки стають потужним інструментом для надання логопедичних послуг, забезпечуючи доступ до корекційних вправ у будь-який зручний для користувача час. Метою даної роботи є розробка програмної реалізації інтерактивної системи для підтримки осіб із порушеннями мовлення. В статті детально описані архітектурні рішення, що були використані під час розробки додатку, його структура та порівняння з вже існуючими аналогами. Особливістю програмного додатку є те, що він орієнтований не лише на дитячу, але й на дорослу аудиторію, а також використовує засоби штучного інтелекту для реалізації функціоналу, пов'язаного з відтворенням скоромовок. Очікується, що досліджувана програмна система сприятиме покращенню методів роботи логопедів та підвищенню якості надання логопедичних послуг за допомогою мобільних технологій.
АРХІТЕКТУРА ТА МЕТОДОЛОГІЯ ІНТЕГРАЦІЙНОГО ФРЕЙМВОРКУ ДЛЯ РОЗРОБКИ ПРОГРАМНОГО ЗАБЕЗПЕЧЕННЯ НА ОСНОВІ КОНЦЕПЦІЇ VIEWPOINTS
Authors: СТИСЛО Тарас , СТИСЛО Оксана , ДЕМЧИНА Микола , БІЛОУС Василь
Published: July 2024

В роботі представлено структуру ViewPoints для розподіленої багатонапрямленої розробки програмного забезпечення, наведено структурні елементи фреймворку, ViewPoints і шаблони ViewPoint, представлено можливості підтримки ViewPoint-Oriented Software Engineering (VOSE), а також представлено розробку методів у структурі ViewPoints і досліджено як метод розробляється та створюється розробниками і подається як інженерний процес, що впливає на спосіб використання методу.
Short-Form Video Content and Consumer Engagement in Digital Landscapes
Authors: Manic Marius
Published: July 2024

Short-form video content has revolutionized marketing by aligning with the rapid consumption habits of digital audiences perfectly, offering marketers a dynamic tool to capture attention quickly and effectively. Its ability to engage viewers through emotionally resonant, story-driven content that is both accessible and shareable underscores its growing dominance in digital advertising strategies. As digital landscapes evolve, so will the strategies that drive consumer engagement. Short-form video is an important part of this evolution, promising exciting opportunities for innovation and rapid connection with the consumer.
Transaksi Peralihan Hak Atas Tanah dan/atau Bangunan Dalam Perjanjian Pengikatan Jual Beli (PPJB)
Authors: Nabila Zula Jihaan
Published: July 2024

Perjanjian pengikatan jual beli (PPJB), merupakan perjanjian pendahuluan yang pengaturan secara khususnya tidak diatur, mengenai aturan dalam pembuatan PPJB mengikuti syarat sahnya suatu perjanjian yaitu Pasal 1320 KUHPerdata dan mengikatnya suatu perjanjian sesuai dengan Pasal 1338 KUHPerdata. Perjanjian jual beli tanah/bangunan adalah suatu transaksi yang dilakukan oleh pihak penjual dan pembeli untuk saling mengikatkan melalui perjanjian yang mana terdapat persetujuan antara para pihak untuk saling mengikatkan diri dengan satu pihak dalam melakukan penyerahan suatu kebendaan kepada pihak lainnya yang akan melakukan pembayaran sesuai dengan yang telah diperjanjikan. PPJB dalam transaksi jual beli tanah/bangunan merupakan transaksi yang besar dan sebaiknya dibuat di hadapan pejabat berwenang yaitu notaris agar kekuatannya mengikat. Hak atas tanah/bangunan dapat beralih apabila telah dilakukan pendaftaran pada kantor pertanahan, yang mana dalam transaksinya telah dilaksanakan sebagaimana semestinya dan telah dibuatkan Akta jual Beli (AJB) sebagai syarat dalam proses peralihan hak atas tanah/bangunan di lakukan para pihak di hadapan PPAT. Penting dibuatnya PPJB karena dalam praktiknya sering menimbulkan permasalahan dikemudian hari, oleh karena itu dalam penulisan artikel ini, akan dijelaskan mengenai kekuatan hukum dari PPJB dan perlindungan hukum bagi para pihak dalam PPJB. Metode penelitian yang digunakan adalah studi doktrinal, penelitian ini mengacu pada peraturan hukum yang sumbernya dari hukum positif. Penelitian dilakukan dengan melakukan pengumpulan dan kepustakaan (library reserch) atau data sekunder terutama dari sisi peraturan perundang-undangan dan norma hukum yang dapat dikaitkan dengan permasalahan dalam penelitian ini, nantinya bertujuan supaya dapat diketahui kekuatan hukum dan perlindungan hukum dari pembuatan PPJB sebagai perjanjian pendahuluan untuk proses pembuatan AJB.
ANALISIS PENATAAN PEMUKIMAN DI SENTANI KABUPATEN JAYAPURA
Authors: Lembang Nataniel , Rante Harmonis , Rusim Dewi Ana
Published: July 2024

The handling of slum settlements has been mandated through Presidential Regulation No. 18 of 2020 concerning the 2020-2024 National Medium Term Plan Development Plan (RPJMN). Sentani City as the center of government in Jayapura Regency also needs to make arrangements for existing slum settlements. This was followed up through the Decree of the Regent of Jayapura Regency No. 188.4/332 of 2020 concerning Determination of the Location of Slum Housing and Slum Settlement in Jayapura Regency in 2020. This study aims to identify and analyze the condition of slum settlements in Jayapura Regency and develop strategies and handling them. Primary data collection was done through direct observation, documentation and field interviews. Secondary data through coordination with related parties, information through the media and related research journals. Data analysis was carried out qualitatively. The results showed that there were 49.09% of houses that were uninhabitable, only 10.38% of drinking water was provided for households, there were 3,655 households that had not been served by electricity, still high house construction and construction without environmental impact analysis and building permit regulations, unavailability of public cemeteries owned by local governments, high cases of land grabbing and blocking, many environmental roads are in a damaged condition, inadequate drainage in residential areas, there are still many lands and lands that have not been certified and land management has not been optimal. The strategy and handling of slum settlements in Jayapura Regency is referring to the Jayapura Regency's 2017-2022 medium-term development vision, potential area of Jayapura Regency, the problem of the uneven distribution pattern of infrastructure and facilities in the Jayapura Regency area and the prospect of developing new residential areas..
KAJIAN INFRASTRUKTUR DAN PEMELIHARAAN TERMINAL YOUTEFA, KOTA JAYAPURA
Authors: Maay George , Rante Harmonis , Rusim Dewi Ana
Published: July 2024

Transportation is a derivative need that arises due to demand for commodities that differ from one region to another. Transportation is formed by several components including infrastructure and people. Therefore, at travel meeting points between one region and another, a place that can guarantee smooth transfers, namely the terminal, is needed. Youtefa Terminal is one of the terminals in Jayapura City. The location of the Youtefa Terminal is integrated with the Youtefa Market so that the existence of the Youtefa Terminal is very important for the community. The research location is Youtefa Terminal. The analytical method used is a qualitative method. The results showed that the existing infrastructure at Youtefa Terminal, such as the parking area, passenger waiting room and terminal office, was in very poor condition. So in order to optimize the condition of the Youtefa Terminal, it is necessary to develop a Service Strategy and Infrastructure Maintenance in the Youtefa Terminal.
Curcumin and amaranth as potential anti-inflammatory and protective agents in bone and joint diseases
Authors: Cuero Antolin Cinthia Nayeli , Cerecero Aguirre Patricia , Peyruchaud Olivier , Hassan Moustafa Wael Hegazy , Colin Ferreyra María del Carmen
Published: July 2024

There has been growing interest in medical research focused on natural products. As a result of the ancestral knowledge passed down through generations and the demands of our current era, there has been an increased demand for new strategies and the search for new molecules with therapeutic potential. This increase is due to new technologies, the evolution of diseases, and the emergence of new ones. In this review, we focus on the work and relevance of Curcumin research, which is one of the main components of Curcuma longa. Additionally, we explore Amaranth in its various reported species and components (seed, leaf, stem) studied. The focus is on the anti-inflammatory therapeutic potential, not only in one, but in different diseases characterized by inflammation and bone destruction. We aim to analyze the possible molecular mechanisms by which curcumin and amaranth act as well as data currently obtained from different studies. This review aims to open a new perspective to the investigation of these compounds in the field of diseases characterized by inflammation and bone destruction.
Keywords: curcumin, amaranth, treatment, inflammation, bone.
The Inflammation-Induced Dysregulation of Reelin Homeostasis Hypothesis of Alzheimer’s Disease
Authors: Reive Brady S. , Lau Victor , Sánchez-Lafuente Carla L. , Henri-Bhargava Alexandre , Kalynchuk Lisa E. , Tremblay Marie-Ève , Caruncho Hector J.
Published: July 2024

Alzheimer’s disease (AD) accounts for most dementia cases, but we lack a complete understanding of the mechanisms responsible for the core pathology associated with the disease (e.g., amyloid plaque and neurofibrillary tangles). Inflammation has been identified as a key contributor of AD pathology, with recent evidence pointing towards Reelin dysregulation as being associated with inflammation. Here we describe Reelin signaling and outline existing research involving Reelin signaling in AD and inflammation. Research is described pertaining to the inflammatory and immunological functions of Reelin before we propose a mechanism through which inflammation renders Reelin susceptible to dysregulation resulting in the induction and exacerbation of AD pathology. Based on this hypothesis, it is predicted that disorders of both inflammation (including peripheral inflammation and neuroinflammation) and Reelin dysregulation (including disorders associated with upregulated Reelin expression and disorders of Reelin downregulation) have elevated risk of developing AD. We conclude with a description of AD risk in various disorders involving Reelin dysregulation and inflammation.
Phosphodiesterase-5 Inhibitors and Dementia Risk: Confounding by Indication in Real-World Studies
Authors: Wu Che-Yuan , Swardfager Walter
Published: July 2024

Pharmacoepidemiologic studies using routinely collected data allow researchers to propose drugs for repurposing trials for dementia prevention or treatment. A recent cohort study reported a 54% lower dementia risk among users of sildenafil compared to users of certain cardiovascular medications. We caution that “confounding by indication” can arise when outcomes are compared between a drug of interest and an inappropriate comparator. Here, we emphasize important considerations in selecting an active comparator. We assess the implications of substantial risk of confounding by indication in pharmacoepidemiologic studies linking phosphodiesterase-5 inhibitors to lower dementia risk.
Micronuclei as an indicator of genotoxic change in epithelial cells of buccal mucosa after panoramic radiographs
Authors: Batool Syeda Aqsa , Chaudhry Sana , Munir Nadia , Inayat Naveed , Suleman Ghazala , Ahmed Abdul Razzaq , Al-Qarni Mohammed A. , Chaturvedi Mudita , Cicciù Marco , Minervini Giuseppe
Published: July 2024

BACKGROUND: The radiation released at the time of dental panoramic radiographs causes genotoxic and cytotoxic effects on epithelial cells. OBJECTIVE: This research aimed to evaluate the changes in the frequencies of micronucleated cells in patients’ buccal epithelial cells following dental panoramic radiography. METHODS: 74 patients were recruited for the study who were advised for panoramic radiographs. Using a wooden spatula, the buccal epithelial cells were scraped from both cheeks before to panoramic radiation exposure and ten days after the panoramic radiation exposure. Giemsa stain was used to stain the cells, and 500 cells were scored on a slide to determine the frequency of micronuclei. To determine the difference between the frequency of micronuclei before and after radiation exposure, a paired t-test was used in the statistical analysis. RESULTS: The proportion of micronuclei cells was 0.11% before radiation exposure and 0.57% following radiation exposure after 10 days. A statistically significant increase in the frequencies of micronuclei was noted after radiation exposure values. CONCLUSION: This study revealed the genotoxicity of epithelial cells with dental panoramic radiation exposure. It is advised to reduce the use of such radiographs and to use only when there is no other diagnostic tool that is helpful or when absolutely essential.
Relationship between Sexist Attitudes and Sexual Harassment: Investigating the Mediating Role of Authoritarianism
Authors: Younas Faiz , Mahmood Smavia , Qayyum Shazia
Published: July 2024

This research aimed to investigate the inter-relational dynamics between ambivalent sexism, authoritarianism, and attitudes towards sexual harassment in young adult men. It was hypothesized that a) there would be correlations between the study variables, b) both ambivalent sexism and authoritarianism would predict sexual harassment attitudes and c) authoritarianism would mediate between ambivalent sexism and sexual harassment attitudes. Following APA-mandated research ethics, a sample of 239 young adult men (Mage= 24.34, SDage=2.97) was conveniently recruited and assessed through the Ambivalent Sexism Inventory, the Aggression-Submission-Conventionalism Scale, and the Sexual Harassment Attitude Scale. Findings indicated that while sexual harassment attitudes were found to be negatively related to ambivalent sexism, they had a positive relationship with authoritarianism. Further, authoritarianism appeared to predict sexual harassment attitudes and also emerged as a partial mediator between ambivalent sexism and sexual harassment attitudes.  The findings of this research offer considerable implications for academicians, researchers, gender experts and policymakers as it provides them with the latest empirical and apt results.
Assessment of Human Interleukin-24 Expression in Thalassemic Patients and Investigation of Current Prescription Pattern in Thalassemia
Authors: Saeed Babar , Busharat Mariam , Farooq Fardah , Ikram Muhammad , Uddin Zia , Shah Nabi , Amirzada Muhammad Imran
Published: July 2024

Interleukin (IL)-24 or melanoma differentiation-associated gene-7 (MDA7) belongs to the family of cytokines initially obtained from malignant tissues and manifests itself in various types of cells (of a large size). Thus, they play a crucial part in anemias. The current study aims to analyze the activation and involvement of IL-4 in thalassemia patients. For this purpose, a study population of 50 patients was randomly selected to study the prescription pattern and blood samples for the activation of IL-24 by utilizing the RT-PCR procedure. Extraction of mRNA was followed by cDNA synthesis, further followed by real-time polymerase chain reaction (RT-PCR). Based on RNA extraction, 31 samples were selected to study the expression of MDA-7 gene in blood samples. Patients were randomly divided into two groups based on the number of transfusions at the time of blood sampling. Group 1 comprised patients with more than 100 transfusions, while Group 2 comprised patients with less than 100 transfusions. Prescription patterns showed the recommendation of approximately the same classes of drugs which are particularly used for thalassemic patients. The findings from gel electrophoresis were analyzed visually. These showed the IL-24 expression in the majority of patients included in Group 1, while no expression was found in individuals included in Group 2. The results revealed the relationship of IL-24 with thalassemia owing to its expression; however, the exact mechanism and contributing factors still remain unknown. Hence, further investigation is needed to rule out the involvement of IL-24 in thalassemia.
Comparative Analysis of the Impact of Positional Release Technique (PRT) and Ischemic Compression (IC) on Headache Disability and Pain in Cervicogenic Headache (CGH) Patients
Authors: Ahmad Shahbaz , Umar Muhammad , Asim Muhammad , Khan Zohaib , Ahmed Iqbal Azeem
Published: July 2024

Headache originating from the bony structures or soft tissues of the neck is commonly known as cervicogenic headache. This study was conducted to determine the effects of the positional release technique (PRT) and ischemic compression (IC) on pain and headache disability among patients with cervicogenic headache (CGH). For this purpose, a randomized clinical trial was conducted. Data was collected from the Physiotherapy Department of Sharif Medical Complex, Lahore. A total of 36 CGH patients were assigned into two groups, randomly. The first group was treated with PRT and the other with IC. Both groups were given 12 sessions of therapy over a span of 4-weeks. HDI (Headache Disability Index) and NPRS (Numeric Pain Rating Scale) were used to measure the treatment effect on pain and headache disability before and after treatment. Among the participants (N = 36), the mean age of Group A and Group B was 26.22 ± 2.90 and 24.55 ± 2.55, respectively. A significant difference was found between the mean values of pre- and post-HDI and NPRS, with p-values 0.025 and 0.031, respectively and after treatment p value was 0.001 & 0.00 respectively. The results favoured the use of PRT because there was more variation in the mean values of PRT as compared to IC. Also, the mean values of pre- and post-HDI and NPRS scores varied significantly. Notably, a significant difference was not found between the mean values of both techniques at the beginning of treatment (pre-treatment). However, a significant difference was observed between the mean values of both techniques following treatment (post-treatment) in favour of PRT, since the mean values of PRT varied more than those of IC.
Исследование фазообразования и сопутствующих процессов
при реакционном спекании порошков Ti+CuO
Authors: Сафронова Валерия Сергеевна , Князева Анна Георгиевна , Коростелева Елена Николаевна
Published: July 2024

В данной работе представлены результаты эксперимента по жидкофазному спеканиюпорошковых систем Ti-CuO и Al-Ti-CuO.Выявлено, что превращения в смеси начинаются до достижения температуры плавления легкоплавких компонентов.
Предложена термокинетическая модель процесса с суммарной реакцией. Представлены результаты исследования режима нагрева и исходных материалов на степень превращения и температуру. Продемонстрировано влияние возникновения жидкой фазы на температуру образца. Интерес к исследованиюсостоит в установлении оптимального соотношения исходных компонентов и режима нагрева с целью получения металломатричного композита на основе куприда титана. Поэтому в дальнейших исследованиях планируется учет в модели детальной кинетики реакций для разных смесей и эволюции пористости.
Crisis of Human Rights of Refugees and Asylum Seekers in Japan
Authors: Miyamoto Erika
Published: July 2024

The year 2022 marks the 40th anniversary of the start of Japan’s refugee recognition system. Despite being a prosperous democracy and a staunch supporter of the international system, Japan has consistently admitted only a small number of refugees. According to the Immigration Services Agency of Japan, the number of people recognised as refugees in 2022 reached a record high of 202, while those not recognised exceeded 10,000. Furthermore, the legislative bill to revise the Immigration Control Law, passed by the House of Councillors Judicial Committee on June 8, 2023, limits applications for refugee recognition to twice in principle. From the third application onwards, there is a possibility for forced deportation to the applicants’ home countries. This legislative bill can be seen as violating the human rights of refugees and asylum-seekers, contravening international human rights law, and the 1951 Convention Relating to the Status of Refugees. Therefore, this article specifically explores Japan’s stronger stance on control over protection, whether its low recognition rate indicates non-compliance with international refugee protection criteria, and the reasons behind this. These aspects will be methodically examined, employing rationalist, normative, and domestic institutional theories of international conformity. Finally, the article will suggest measures to improve Japan’s refugee recognition rate and enhance the protection of the human rights of refugees and asylum seekers.
The Crime of Ecocide through Human Rights Approach
Authors: Sziebig Orsolya Johanna
Published: July 2024

The environment is often called the “silent victim of war” – the case is not different in the Russo–Ukrainian armed conflict. Since 2014, nature − home to 35% of European biodiversity and varied natural habitats − has suffered a tremendous loss in Ukraine. The war has been responsible for the emission of 33 m tonnes of CO2 , and postwar reconstruction is estimated to generate even more. Additional environmental concerns include extensive pollution, degradation of natural habitats, and species extinction. Regarding the new data, more than 2 thousand events can be considered ecocide. Ecocide is the destruction of the natural environment by deliberate or negligent human action. Transboundary environmental harm is also a pressing issue, as pollution “travels” by wind, air, and water to other countries. Ecocide is a new yet old concept concerning severe environmental destruction. In the last decade, a debate has emerged concerning legislation, definition and enforcement. Instead of international criminal law, many believe that the solution will be the human rights approach. Meanwhile, the right to a healthy environment, initially not included in “traditional” human rights conventions, is getting more attention worldwide and in Europe. Recently, the European Economic and Social Committee adopted an own-initiative opinion on the right to a healthy environment in the EU in the context of the war. The aim is to criminalise Russia’s actions under European law and ensure environmental protection to safeguard fundamental rights. In the paper, the author would like to focus on the parallel development of the right to a healthy environment and ecocide.
Sistem Pendukung Keputusan Menggunakan Metode WASPAS Untuk Pemilihan Aplikasi Manajemen Bisnis dan Keuangan
Authors: Ramadhan Idrus , Nugroho Nurhasan , Kurniawanto Hadi , Warta Joni
Published: July 2024

Dalam bisnis yang dinamis dan kompleks, manajemen efektif sangat penting, terutama dalam penggunaan aplikasi bisnis dan keuangan. Namun, banyaknya aplikasi yang tersedia membuat pemilihan aplikasi yang tepat menjadi rumit dan memakan waktu. Pengguna harus meninjau setiap aplikasi sebelum memutuskan, yang sering kali sulit dan memerlukan waktu lama karena kurangnya pemahaman lengkap tentang semua opsi. Penelitian ini bertujuan mengembangkan Sistem Pendukung Keputusan (SPK) yang memanfaatkan metode WASPAS (Weighted Aggregated Sum Product Assessment) untuk memfasilitasi pemilihan aplikasi manajemen bisnis dan keuangan yang ideal serta mempermudah proses pengambilan keputusan. Metode WASPAS digunakan karena kemampuannya dalam mengevaluasi berbagai alternatif dengan memadukan pendekatan penjumlahan terbobot dan perkalian terbobot, menghasilkan evaluasi yang lebih seimbang dan objektif. Penelitian ini menghasilkan sistem yang dapat melakukan perhitungan otomatis dengan metode WASPAS dan menyajikan rekomendasi alternatif terbaik dalam bentuk peringkat. Selain itu, SPK yang dibangun memperoleh skor rata-rata 91,25% berdasarkan pengujian usability, menunjukkan bahwa sistem ini mudah digunakan dan layak diimplementasikan.
The Effect of Using Instructional Media in Alef Education to Improve Listening Skills
Authors: Nuroh Nuroh , Ubaidillah Ubaidillah
Published: July 2024

This study aims to find out how the use of Alef Education learning media improves listening skills (a quasi-experimental study in class eleventh grade students in Islamic Senior High School 1 Kab. Serang) and the effect of using Alef Education learning media on improving listening skills (a quasi-experimental study in class eleventh grade student’ in Islamic Senior High School 1 Kab. Serang). Researchers use quantitative research methods using the quasi-experimental design and actual design experimental methods, namely experiment and control classes. The population of this study was 249 students of class eleven, and the sample used amounted to 36 students. The sampling technique used probably sampling with simple random sampling, which is a random sampling from the population because the population is considered homogeneous if the number of subjects is less than 100. The data collection methods used are observation, interview, documentation, pre-test, and post-test. The effect of using Alef Education learning is calculated from the pre-test and post-test with the arithmetic t-method > t-table 5,168 > 2,032. It can be concluded that there is an influence on listening skills in Alef Education learning.
PENGUATAN KURIKULUM KKNI PRODI PAI DALAM MENINGKATKAN KUALITAS PEMBELAJARAN PAI DI SMAN KABUPATEN PANDEGLANG
Authors: Zuhri Saefudin , Nadiroh Yahdinil Firda
Published: July 2024

. Penelitian ini bertujuan untuk  mengetahui dan menganalisis relevansi muatan kurikulum KKNI program studi Pendidikan Agama Islam dengan kompetensi dasar pada pembelajaran mata pelajaran Pendidikan Agama Islam di Sekolah Menengah Atas di Kabupaten Pandeglang. Jenis Penelitian ini adalah penelitian kualitatif descriptive yang menyuguhkan data relevan dengan kondisi data nyata denga menggunakan mix method. Data-data yang dipakai di dalam penelitian ini merupakan data sekunder yang berasal dari (1) Dosen-dosen prodi PAI UIN Sultan Maulana Hasanuddin Banten pengampu mata kuliah kegamaan dalam bentuk Rencana Pembelajaran Semester (RPS); (2) Guru-guru SMAN di Kabupaten Pandeglang pengampu mata pelajaran PAI dalam bentuk dokumen KI/KD dan Silabus. Berdasarkan hasil penelitian disimpulkan bahwa terdapat relevansi atau kesesuaian antara kurikulum KKNI prodi PAI UIN Sultan Maulana Hasanuddin Banten dengan kurikulum SMAN pada mata pelajaran PAI. Relavansi tersebut dapat terlihat dari besaran prosentase yang tergambar pada setiap kelas, yakni (1) Tingkat kesesuaian kurikulum pada kelas X dideskripsikan 65,90% - 77,27% menunjukan sangat sesuai. (2) Tingkat kesesuaian kurikulum pada kelas XI menunjukan angka 68,18% - 81,81%. (3) Tingkat kesesuaian kurikulum pada kelas XII didapatkan prosentase 56,25% - 87,5%.
Kata kunci: Relevansi, KKNI, Kurikulum PAI
SOURCE MATERIAL FOR HETEROSIS SELECTION OF SWEET PEPPER
Authors: Pylypenko L. V. , Melnyk O. V. , Mytenko I. M. , Huliak N. V. , Tolinova T. O.
Published: July 2024

The purpose of the research is to identify promising genotypes of sweet pepper source material based on the main economically valuable traits for further use in heterosis selection. Methods: Field, laboratory, measurement-weight, statistical. Results: The study highlighted that the best samples of source material for breeding sweet pepper for earliness were the genotypes: Iga, L. 183/331, Polet, Rewia, which reach technical maturity in 99–103 days. The most large-fruited samples compared to the standard variety Snihur (12; 6 cm) were: Robertina (13; 7 cm), Veronika (15; 7 cm), Ania (19; 7 cm), Herakl (16; 7 cm), Lai lak bell (13; 7 cm), Fatima (16; 7 cm), Horticolas (17; 9 cm), Enei (13; 8 cm). It was found that the highest number of fruits per plant was in samples: Druzhok (11 pcs.); L. 183/331 (12 pcs.); L. 184/332 (16 pcs.); Kurtovskakapia (11 pcs.); Oda (11 pcs.); Tsyhanskyi baron (12 pcs.); King kong (11 pcs.); Chornyi kin (11 pcs.). The samples highlighted for "average commercial fruit weight" were: Ania (197 g); Herakl (174 g); Horticolas (246 g); Bel hoi (189 g); Enei (177 g); Tonenoelloy (186 g). The highest fruit productivity of sweet pepper was observed in the genotypes: Aivengo (1210 g/plant); Alexia (1205 g/plant); Druzhok (1326 g/plant); Ania (1482 g/plant); Anastasiia (1320 g/plant); Iga (1246 g/plant); Herakl (1436 g/plant); Horticolas (1331 g/plant); King kong (1256 g/plant). Conclusions: Thus, the conducted breeding research allowed identifying the main genotypes that combine several important quantitative traits – these are L. 183/331, L 184/332, Ania, Herakl, Horticolas, King kong.