bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of Left Ventricular Hypertrophy Incidence and Antihypertensive Therapy Efficacy in Hypertensive Patients
Authors: Khan Samia Perwaiz , Majeed Harris , Izhar Safia , Kanwal Shaista , Ahmed Raeeqah , Munawar Rimsha , Meraj Somal , Naz Laiba
Published: April 2024

Objectives: This study aimed to assess the incidence of left ventricular hypertrophy (LVH) in hypertensive individuals in Karachi, Pakistan, and to evaluate the effectiveness of antihypertensive therapy in preventing LVH.
Methodology: A total of 200 hypertensive patients were referred from the Cardiac OPD to the Radiology department of Medicare Cardiac and General Hospital, Karachi, for echocardiography. Echocardiographic measurements of cardiac chambers were performed by expert echocardiographers, and left ventricular mass (LVM) was calculated using the formula recommended by the American Society of Echocardiography.
Results: Among the hypertensive patients, 100 had uncontrolled blood pressure (≥140/90 mmHg) while 100 had controlled blood pressure (≤130/80 mmHg). The female-to-male ratio was 3:1, with ages ranging from 21 to 80 years. Patients with uncontrolled hypertension exhibited a higher mean body mass index (29 ± 5 kg/m2) and significantly elevated LVM (mean 154 ± 4 g/m2). Angiotensin receptor inhibitors were the most commonly prescribed and effective antihypertensive agents, either as monotherapy or in combination therapy (60%), demonstrating utility in preventing LVH.
Conclusion: This study highlights a high incidence of LVH in uncontrolled hypertensive individuals compared to those with controlled hypertension. Transthoracic echocardiography emerged as a highly valuable, non-invasive tool for measuring LVM and assessing the effectiveness of antihypertensive therapy.
Comparison of In-Hospital Outcomes between Heart Failure Patients with Reduced and Preserved Ejection Fraction: A Single-Center Cross-Sectional Study
Authors: Sohail Huma , Khaliq Kubra , Irfan Ghazala , Amir Kanwal
Published: April 2024

Objectives: Heart failure (HF) poses a significant global health burden, characterized by inadequate cardiac output and systemic organ dysfunction. This study aimed to compare in-hospital outcomes between patients with reduced (HFrEF) and preserved (HFpEF) ejection fraction presenting with congestive heart failure.
Methodology: A cross-sectional, prospective study was conducted at the Department of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Pakistan, from July 2022 to January 2023. Patients aged 35 to 80 years with congestive heart failure were included. Ejection fraction status, demographic data, and clinical parameters were assessed, with in-hospital mortality as the primary outcome.
Results: Among 196 patients, 91 (46.4%) had HFrEF, and 105 (53.6%) had HFpEF. In-hospital mortality occurred in 23 (11.7%) patients. Mortality rates were significantly higher in HFrEF patients compared to HFpEF patients (17.6% vs. 6.7%, p=0.018). Age (>60 years) and diabetes mellitus were significantly associated with in-hospital mortality (p=0.001 and p=0.036, respectively).
Conclusion: This study highlights significantly higher in-hospital mortality rates in patients with reduced ejection fraction compared to preserved ejection fraction, underscoring the importance of considering ejection fraction status in assessing prognosis and guiding management strategies for patients with congestive heart failure.
Exploring the Role of Non-HDL Cholesterol in Acute Coronary Syndrome: A Case-Control Study
Authors: Mohammedi Mustafa Khamees Mohsin , Altaweel Rafid Bashir , Gburi Ahmed Kareem Kadhim Al
Published: April 2024

Objectives: This case-control study aimed to investigate the association between non-high-density lipoprotein (non-HDL) cholesterol levels and acute coronary syndrome (ACS) among individuals not recently treated with statins.
Methodology: A total of 100 participants with ACS, who had not received recent statin therapy, were selected from the Coronary Care Unit (CCU) at Al-Kadhimiyah Hospital in Baghdad, Iraq. Controls, matching the eligibility criteria of cases except for ACS symptoms, were randomly chosen from the same hospital. Both groups met criteria including age over 40, and a history of diabetes mellitus, hypertension, smoking, and obesity. Statistical significance was set at p < 0.05.
Results: The study found a significant independent association between elevated non-HDL cholesterol levels and ACS, with an average non-HDL level of 154.2 mg/dl (normal: 130 mg/dl) among ACS cases (p < 0.001), compared to 120 mg/dl in controls. Elevated non-HDL levels were also correlated with increased BMI (p = 0.01, r = 0.3) and various lipid markers (p < 0.05), except HDL.
Conclusion: Elevated non-HDL cholesterol levels upon admission may serve as a potential indicator of ACS risk. These findings underscore the importance of non-HDL cholesterol assessment in ACS risk stratification and management.
Correlation between Post-operative Serum Lactate Levels and Low Cardiac Output Syndrome in Patients Undergoing Coronary Artery Bypass Grafting Surgery: A Prospective Study in a Tertiary Care Hospital
Authors: Khan Muhammad Farhan , Khahro Adnan Ali , Pathan Iqbal Hussain , Nek Naveed , Bughio Hosh Muhammad , Dar Mudassir Iqbal
Published: April 2024

Objectives: This study aimed to assess the correlation between the development of low cardiac output syndrome (LCOS) and post-operative serum lactate levels in patients undergoing coronary artery bypass grafting (CABG) surgery at a tertiary care hospital.
Methodology: A prospective cross-sectional study was conducted from January to June 2021, involving 50 patients undergoing CABG surgery with cardiopulmonary bypass. Arterial samples were obtained immediately post-surgery and at six, twelve, and twenty-four-hour intervals post-operatively. The association between lactate levels and the occurrence of LCOS, need for inotropic support, and intra-aortic balloon pump (IABP) utilization was evaluated.
Results: The study comprised predominantly male patients (84%). Patients were categorized into two groups based on lactate levels: Group 1 (> 4 mmol/L) and Group 2 (< 4 mmol/L). In Group 1, 32% of patients developed LCOS, 10% required IABP, and 20% needed inotropic and vasopressor support. Immediately post-CABG, the mean lactate level was 7.5 mmol/L, with 3% requiring IABP and 20% needing double inotropic support. Lactate levels decreased over time, with mean levels at six, twelve, and twenty-four hours post-surgery being 6.3 mmol/L, 3.8 mmol/L, and 3.3 mmol/L, respectively. Correspondingly, the need for IABP and inotropic support decreased. LCOS occurrence within 24 hours post-surgery correlated significantly with elevated lactate levels (p < 0.05).
Conclusion: Elevated lactate levels were associated with the development of LCOS within 24 hours post-CABG surgery. Monitoring lactate levels postoperatively may serve as a valuable tool in predicting and managing LCOS in CABG patients.
Venous-Only Transcatheter Closure: A Safe and Effective Strategy for Patent Ductus Arteriosus
Authors: Kanwal Asma , Sheikh Abdul Malik , Akbar Tauqeer , Sehar Tayyaba , Sheikh Kiran Azim , Talat Sidra
Published: April 2024

Objectives: This study aimed to assess the feasibility and effectiveness of transcatheter device closure of patent ductus arteriosus (PDA) exclusively through an isolated venous route.
Methodology: A retrospective descriptive study was conducted at the Rawalpindi Institute of Cardiology. Patient data from 2019 to 2023 undergoing PDA closure using transcatheter devices were analyzed. PDA diagnosis was established via echocardiography, and the procedure was performed solely through a venous line under fluoroscopy, omitting the traditional method of using both arterial and venous lines.
Results: A total of 212 patients underwent transcatheter PDA closure through a venous-only route, with ages ranging from 6 months to 14 years. The mean weight was 10.07 kg (range: 5 kg to 27 kg, SD 4.43). The average procedure time was 30 ± 10.3 minutes (range: 15.0 to 65 minutes), and fluoroscopy time was 5.4 ± 3.18 minutes (range: 2.1 to 19 minutes). Immediate closure was achieved in all patients, with no residual leaks or device embolization observed. Additionally, there were no reported complications such as arrhythmia, vascular access issues, or significant blood loss. No cases of aortic or pulmonary stenosis were identified, and no deaths occurred. All patients were discharged within 48 hours post-procedure.
Conclusion: Transcatheter closure of PDA exclusively through the venous route, without the use of an arterial line, demonstrates itself as an effective and safe method for PDA closure.
Leveraging Clinical Pharmacy Expertise for Pediatric Cardiology in Low and Middle-Income Country
Authors: Batool Aniqa , Shamim Sumbul , Mohsin Muhammad
Published: April 2024

Pharmacists are universally regarded as an integral component in the therapeutic prescription, particularly within the realm in pediatric population. As the drastic increase in prevalence of cardiovascular diseases in pediatrics in Pakistan harness numerous opportunities for pharmacists to involve in clinical activities such as, to evaluate treatment regimens, therapeutic monitoring, adverse event monitoring, counseling and intervene as needed appropriately in collaboration with physician to facilitate high care to pediatric patients. However, a comprehensive literature review underscores the dearth of such patient-centered practice in Pakistan in public-health sector specially. In this commentary, we accentuate the indispensable involvement of pharmacist in pediatric cardiac unit of public-sector in low and middle income country to optimized pediatric patients care
Comparison of Dual vs. Triple Antithrombotic Therapy in Non-Valvular AF and Acute Coronary Syndrome: A Malaysian Cohort Study
Authors: Saad Eldowaik Mohamed Salah , Zainal Zainol Akbar , Hisham Shairyzah Ahmed , Mohamed Sahimi , Devi Pavithira
Published: April 2024

Objectives: This study aimed to compare Dual Antithrombotic Therapy (DAT) and Triple Antithrombotic Therapy (TAT) concerning bleeding and thrombosis outcomes in Malaysian patients with non-valvular atrial fibrillation (NVAF) and acute coronary syndrome (ACS), considering demographic characteristics and comorbidities.
Methodology: A retrospective observational cohort study was conducted at Hospital Serdang from January 1, 2020, to May 1, 2022. A total of 206 patients were selected via purposive sampling and divided into two groups. The TAT group received warfarin, clopidogrel, and aspirin, while the DAT group received warfarin and clopidogrel over a 1-year follow-up. Multivariate logistic regression analysis was employed.
Results: A higher incidence of thromboembolic episodes was observed in the DAT group (24.3% vs. 8.7% in the TAT group; adjusted odds ratio (aOR) 4.53, 95% CI 1.806-11.379, P= 0.001), signifying a 4.5-fold increase in thromboembolic events in DAT compared to TAT. Conversely, more bleeding episodes were observed in the TAT group (25.2% vs. 15.5% in the DAT group; aOR 2.22, 95% CI 0.993-4.970, P= 0.52), although the difference was not statistically significant.
Conclusion: The DAT protocol showed significantly more thrombosis episodes than the TAT protocol, while TAT exhibited a non-significant increase in bleeding events compared to DAT at one year follow-up in patients with NVAF and ACS.
Grandparenting and the Mental Well-being of Selected Filipino Grandparents
Authors:   Department of Human and Family Development Studies College of Human Ecology University of the Philippines Los Baños, Philippines, Angelyna J. Garcia Fatima , Felicidad R. Dy Marison ,   Department of Human and Family Development Studies College of Human Ecology University of the Philippines Los Baños, Philippines
Published: April 2024

This study determined the impact of caring for grandchildren on the mental well-being of elderly grandparents. Specifically, it determined the length of grandparenting, number and ages of grandchildren living with them, influential grandparenting experiences, level of mental well-being, and impact of the grandparenting role to the mental well-being of the grandparents. Respondents were 96 Filipino senior citizens residing in Calamba City, Laguna. An interview schedule was utilized for data gathering. Results showed a weak relationship between age of grandchildren (p = 0.284; p > 0.05) and number of grandchildren (p =0.780; p > 0.05) with the level of mental well-being. The length of grandparenting (p = 0.011; p < 0.05) had a significant effect on the level of mental well-being of the grandparents. Regression analysis showed that those who became grandparents at the age of 46-55 are more likely to have mental well-being scores five times lower than those who do not belong to this age category. Grandparenting may become stressful due to the added responsibility of childcare. However, grandparenting is considered a fulfilling responsibility and gives a rewarding feeling. In totality, grandparenting positively heightens mental well-being.
The Interplay of Motivation, Skills, and Promotions: A Bootstrapped Analysis of MBA Graduates through the Lens of Intelligent Career Theory
Authors:   Business Cluster, Professional School, University of Mindanao, Davao City, Philippines, Montano Vicente , Valdez Clyde Abner ,   College of Business Administration Education, University of Mindanao
Published: April 2024

This tracer study investigates the relationship between the reasons for enrolling in an MBA program (Know-Why), competencies learned during the program (Know-How), and subsequent career promotions (Know-Who) among MBA graduates, guided by the Intelligent Career Theory Framework. The data the respondents furnished is bootstrapped, and the Phi coefficient revealed a statistically significant positive correlation between motivation to enroll and reported acquisition of relevant competencies (Φ = 0.620), supporting the ICTF motion that clear career goals (Knowing-Why) lead to a more strategic approach to learning (Knowing-How) within the MBA program. However, the link between competencies and promotion after graduation (Φ = 0.451) was weaker and not definitively significant. This conveys that while skills gained through the MBA are valuable (Knowing-How), promotions likely depend on a broader range of factors potentially encompassed by the “Knowing-Whom” aspect of ICTF, such as networking and relationships. These findings highlight the importance of motivation and skill development for MBA graduates while acknowledging the complex interplay of factors influencing career advancement. Recommendations are offered to enhance career development outcomes and inform future research.
The Influence of The Reality Show 'Indonesia’s Next Top Model' on Beauty Perception Among Instagram Followers
Authors:   Faculty of Communication Sciences, Universitas Pancasila, Jakarta, Ratu Khaerunnisa Salsabila , Estaswara Helpris ,   Faculty of Communication Sciences, Universitas Pancasila, Jakarta, Said Mashadi ,   Faculty of Communication Sciences, Universitas Pancasila, Jakarta
Published: April 2024

Reality shows serve as entertainment platforms for society, conveying implicit messages and portrayals that influence how audiences perceive and follow what is presented. Audiences utilize Instagram and YouTube as mediums to engage with the frequency, attention, duration, and appreciation of the reality show "Indonesia’s Next Top Model." Instagram, in particular, serves as an interactive tool through which viewers express comments and appreciation for the show. This study aims to investigate whether there is an influence of reality show content on the perception of female beauty, focusing on the viewers of "Indonesia’s Next Top Model" among the followers of Instagram account @intm_nettv. The research employs a quantitative method with an explanatory research design. The unit of analysis comprises individuals who are followers of the Instagram account @intm_nettv. Data collection is conducted using probability sampling, obtaining a sample of 100 respondents who watch "Indonesia’s Next Top Model." The findings reveal a small influence of 8.2% of the reality show on the perception of female beauty among the followers of Instagram account @intm_nettv. This minimal impact is attributed to the followers' ability to distinguish between the beauty of models and that of other women. Various factors can affect the perception of female beauty, particularly reality show content as entertainment for its audience. Therefore, future research is encouraged to further explore the concept of reality show content and its influence on the perception of female beauty.
Analysis of GPS TEC anomalies associated with Mw > 7 earthquakes in Japan
Authors: Khan Asim , Shah Munawar , Ali Sajjad
Published: April 2024

The Global Positioning System (GPS) provides insights into the Earthquakes (EQs) ionospheric anomalies. Different space-and-ground parameters are used to observe EQ precursors. This paper uses the Total Electron Content (TEC) from nearby operating GPS stations to detect perturbation in the ionosphere before and after four EQs in Japan in 2011. In addition, the TEC variations in relation to the depth and magnitude of the EQs are noticed. The analysis shows significant variations in TEC to depth and magnitude in association with each main shock. TEC value abruption starts on 8 March and continues for 6 days in March. In April, TEC abnormalities start 5 days before and after the man shock. The geomagnetic Kp index is higher than four from March 10 to 12. The anomalies in this study are clearly associated with geomagnetic storms, as the Kp index is active. Moreover, the Dst index is below the negative 50 (nT) in the seismic period of March and April. The ionosphere parameters will define the severity of seismic activity in future.
A comparative analysis and prediction of the economic growth of Pakistan using machine learning models
Authors: Mushtaq Nadia , Bashir Shakila , Mahmood Amjad , Hussain Farhad
Published: April 2024

This article investigates a comparative analysis of machine learning models for Pakistan's Gross Domestic Product (GDP), an important indicator of the nation's economic development. GDP is crucial to assess well-versed decisions. Since machine learning techniques are more sophisticated, much interest has been developed in predicting GDP to handle complex data patterns and enhance prediction accuracy. In this study, we evaluated the performance of a variety of machine learning algorithms like Auto-Regressive Integrated Moving Average (ARIMA), double exponential smoothing, Multilayer Perceptron (MLP), Neural Network Auto-Regressive (NNAR), and hybrid machine learning models on data from 1960 to 2022. The MLP used in Artificial Neural Networks (ANNs) outperforms based on the outcomes. This comparative analysis provides insights into the most suitable model for accurate prediction of Pakistani GDP for the years 2023 to 2032. This article provides a detailed analysis of various machine learning models used to predict Pakistan's GDP accurately. GDP prediction is an essential indicator of a nation's economic development and is crucial in making informed decisions. With the advancements in machine learning techniques, there has been a growing interest in predicting GDP due to their efficiency in handling complex data patterns and improving prediction accuracy.
Enhancing Performance of Software Testing Automation using Selenium Web Grid
Authors: Mr. Sundaramohan S
Published: April 2024

Web application testing is crucial to ensuring software quality and dependability. Selenium, a popular open-source testing framework, is widely used for automating web browsers to perform various testing tasks. One of the key components of Selenium is Selenium WebGrid, a distributed testing infrastructure that allows running tests in parallel across multiple nodes. This paper presents a comprehensive study on measuring the performance of Selenium WebGrid. The objective is to evaluate its efficiency, scalability, and reliability in executing test scripts across different browsers and operating systems. The study compares the performance of Selenium WebGrid with other testing approaches, such as traditional Selenium Grid and single-node Selenium execution. The methodology employed in this study involves designing a set of representative test cases that simulate real-world scenarios. These test cases cover a range of typical web application functionalities, including form submissions, page navigation, and data validation. The performance metrics considered for evaluation include execution time, resource utilization, and test throughput. To measure the performance of Selenium WebGrid, a testbed environment is set up consisting of multiple nodes with different configurations. The test scenarios are executed on the WebGrid infrastructure, and the performance metrics are collected and analyzed. The results are then compared with those obtained from traditional Selenium Grid and single-node Selenium execution to identify the performance advantages and limitations of Selenium WebGrid. It demonstrates the improved scalability and efficiency of WebGrid in executing tests across multiple nodes simultaneously. The results also provide insights into the resource requirements and trade-offs associated with using Selenium WebGrid compared to other testing approaches. This work adds to the body of knowledge by presenting empirical data on Selenium WebGrid's performance characteristics. It serves as a valuable resource for software testing professionals and researchers interested in leveraging Selenium WebGrid for distributed web application testing.
Uma heurística de busca local para o problema de designação de equipes de enfermagem com preferências pessoais
Authors: André Maria Valéria de Carvalho , Silva Hedivigem Luana Rodrigues da , Silva Yuri Laio Teixeira Veras
Published: April 2024

Recentemente, a pesquisa em otimização de saúde tem experimentado um crescimento exponencial, despertando o interesse significativo de pesquisadores e organizações de saúde. Esse aumento de interesse é impulsionado pela complexidade e relevância dos desafios enfrentados pela sociedade, estando diretamente relacionado à necessidade crescente de aprimoramento de processos e à busca por maior eficiência nos sistemas de saúde em escala global. O objetivo deste estudo é desenvolver uma abordagem de otimização, baseada em heurística computacional, para realizar o planejamento e a designação de profissionais de enfermagem em setores hospitalares, visando maximizar tanto as preferências pessoais dos profissionais, como a eficiência nos atendimentos de saúde. O método proposto utiliza um algoritmo heurístico de otimização baseado em busca local com mecanismos de perturbação de solução e vizinhanças de busca eficientes. Os resultados computacionais demonstraram que o método é capaz de realizar designações eficientes de profissionais de enfermagem em setores hospitalares, otimizando a satisfação profissional e a qualidade do serviço prestado. Concluindo, o estudo evidenciou que o método desenvolvido permite uma eficiente gestão e designação de profissionais de enfermagem em ambientes hospitalares, alcançando contribuições científicas e práticas para as áreas de healthcare optimization e administração hospitalar.
The Effect of Environmental Factors on Depression
Authors: Kantipudi Viraj
Published: April 2024

This article delves into the complex effect of environmental factors on depression, shining light onto the multifaceted nature of this mental health condition. By knowing the interaction among genetics, race, poverty, schooling, substance abuse, bodily interest, and the extraordinary hazard posed by the COVID-19 pandemic, we benefit from precious insights into how those elements contribute to the improvement and exacerbation of despair.

Genetic predisposition to melancholy is explored, highlighting how genetic variations can boost vulnerability to depression. Racial and ethnic disparities in melancholy occurrence emphasize the effect of cultural and societal factors. The correlation between poverty and depression is examined, showcasing the bidirectional relationship and the role of socioeconomic stressors. The role of education as a defensive aspect in opposition to melancholy. The relationship among substance abuse and depression is dissected and the effect of physical activity on depression is discussed.

Furthermore, the COVID-19 pandemic's global effect on depression is analyzed, revealing how elements of worry, isolation, disrupted workouts, and economic instability have contributed to a surge in melancholy rates. Despite those situations, there may be growing popularity of the importance of physical fitness, as stigma diminishes knowing how the complicated interplay among environmental factors and depression is crucial for effective mental health guidance. Ongoing research and targeted interventions are necessary to mitigate the dangers of depression and enhance typical well-being. As society strives for better mental health, addressing these environmental elements will become a vital step toward that purpose.
Assessing the Biocompatibility of Ti3C2 MXene Nanosheets with Terrestrial and Aquatic Plant Systems
Authors: Feng Qixiang , Chen Qiang , Gogotsi Yury
Published: April 2024

In this study, the biocompatibility of MXene, an emergent class of two-dimensional nanomaterials, with plant systems was explored. Varying concentrations of Ti3C2-based MXene nanosheets were administered to two distinct plant groups—soil-grown Firecracker Flowers (Crossandra infundibuliformis) and water-based Water Hyacinth (Eichhornia crassipes). Predominantly, MXene was observed to be perceived by plant systems as a contaminant, as evidenced by analysis of collected data and images during our experiement. Stronger biocompatibility with soil plants compared to aquatic plants was demonstrated. Over a 19-day observation period, no disruption to the potted soil ecosystem of Firecracker Flowers was detected due to Ti3C2, while a significant impact on the Water Hyacinth ecosystem was noted. The effect of Ti3C2 on Water Hyacinth was found to be substantial and exhibited characteristics akin to those of typical pollutants. Through advanced techniques such as optical microscopy and Scanning Electron Microscopy (SEM), the assimilation and spatial distribution of Ti3C2 within plant matrices were investigated. Ti3C2 was found to be absorbable by plants, but its diffusion within the plant body was determined to be notably limited. This study sheds light on the potential environmental implications of MXene nanomaterials.
Investigating the Effect of Training Reform on Employee Competencies in the Nigerian Public Sector
Authors: Anas A.A
Published: April 2024

Several reforms were carried out in Nigeria over the period 2004 and 2006. One such reform focused on the reorganization of the training structure of civil service. However, whether such reforms would impart the competency level of employees in the Nigerian public sector. This study examined government reform policy and how it affects the competencies of the employees. Primary data were collected for the study, using a structured questionnaire. The study employed a multi-stage sampling technique to select a total of 672 respondents. The data was analysed using correlation analysis, analysis of variance (ANOVA), and Chi-square statistics. The correlation results showed a positive, strong, and significant relationship between training and employees’ skill acquisition (rho = 0.59, p < 0.05). Similarly, the correlation between training and development of employees and knowledge acquisition was positive, strong, and significant (rho = 0.61, p < 0.05). The result from ANOVA confirmed that training and development significantly enhance the skill (F = 13.947, p < 0.05) and knowledge (F = 9.996, p < 0.05) of Government employees. The results lead to the conclusion that civil service reform has the potential to improve the competency level of employees thereby improving the performance of civil service.
A Phenomenological Study of Outsourcing and Employee Relations Management in Lagos State, Nigeria
Authors: MEJABI Folorunsho , CHUKWUMA Nnenna N. , UDU Ama A , EKEOCHA Hector Onyekachi , MANGTU Dangnan Yohanna , OKHIRIA Vincent Omozojie
Published: April 2024

The objective of the research is to examine the relationship between outsourcing and employee relations management. Researchers in the past have emphasised why companies should outsource based on cost savings and gaining a competitive edge, while others focus on the assumed unpalatable effects of outsourcing. Nevertheless, the impact of outsourcing on the relationship between labour and management has long been understudied. This research used a survey design with a sample size of 100. Responses from 63 employees of the selected organisations comprising twenty-five (25) from outsourced employees and thirty- eight (38) from full-time employees. The data was acquired using a convenience sample approach and analysed using descriptive and inferential statistics. The hypotheses were tested using Chi-Square(X2) with a significance threshold of 0.01. The study established a significant relationship between outsourcing and employee relations management, and the elements that influence outsourcing decisions, which are cost savings, corporate focus, and access to world-class expertise, impacted labour-management relations in organisations. Based on the findings, it was recommended that organisations must find a way to outsource non-core activities, using outsourced individuals who can do it better, thereby focusing on core business operations where they have an edge and can outperform their competition while also managing employee relations through better remuneration, communication, leadership, training and job stability.
Academic Challenges Faced by Adolescent Orphans and Vulnerable Children in Manicaland Province in Zimbabwe
Authors: Chidhumo Vincent , Zambezi Fortunate
Published: April 2024

This study examined the academic challenges faced by adolescent orphans and vulnerable learners from child-headed households attending secondary schools in Zimbabwe’s Manicaland Province. Learners from homes without parents are becoming more and more prevalent, but no one has yet taken notice of them. Using Vygotsky’s sociocultural theory of human learning as the theoretical lens, the researchers scrutinized the phenomenon. Thirty participants were chosen from four secondary schools in the Chimanimani District for the qualitative research study. In-depth data about the academic challenges faced by adolescents who are orphans and vulnerable children was generated through focus group interviews. The thematic approach was employed in the analysis of data and invaluable themes were identified. Ultimately, the study’s conclusions were as follows; facilitators and learners need constant motivation, parents can help supervise learners’ work, and teachers should have access to professional development opportunities. The results indicate that in order to guarantee high-quality instruction, guidance and counseling teachers should receive support and opportunity for ongoing professional development. By utilizing learner-centered methodologies, the teaching and learning process should integrate learners’ real-world experiences to improve the learners’ comprehension of the learning materials covered in class.
Bio-Power of Covid-19: Locating the Transform Ability of Bangladeshi Social Narratives by the Archaeology of Pandemics
Authors: Imran Md. Masood , Rashti Mahisun Binte Wahab
Published: April 2024

This study examines the transform ability of social narratives through the archaeology of pandemics. The dynamics of knowledge-power relationship surrounding COVID-19 as an infectious disease, influenced individual bodies through the enactment of strict laws. Furthermore, this leverage shaped societal narratives through fear amidst crisis by challenging conventional norms. In-depth observation, close-ended one-to-one friendly chatting, and archival documents were used to collect the analytical data. Foucauldian idea of the archaeology of knowledge, sexuality and Agamben’s position ality on bio-power, were all extensively recycled to analyse the normative transfer ability of narratives due to the pandemic bio-power dimension. This research found that the understanding of the transform ability of social narratives has changed due to the hegemonic normative power of acceptance by self-reflexivity on memory journey and living self-experiences.
Effect of Interest Rate on Savings Mobilization in Nigeria
Authors: Obeh Henry Obukohwo , Uzonwanne Maria Chinecherem , Nwogwugwu Collins Uche , Metu Amaka
Published: April 2024

The study examines the extent at which interest rate affects savings mobilization in Nigeria. The study is hinged on the modified variant of McKinnon and Shaw hypothesis that accounts for the link between savings mobilization and interest rate. ARDL model was used in the study to test for co-integration for the long run and the unrestricted error correction model for the short run contemporaneous dynamics. Data gotten from CBN annual report and World Economic Outlook covers the period; 1986-2022 was used for the study. Accordingly, the study finds out that savings mobilization is significant but have negative responsive to changes in nominal interest rate both in the short run and long run. Also, the study further finds out that the effect of prime lending rate on savings mobilization is significant but has positive response in long run as against its significant negative effect in the short run. Thirdly, it was observed that maximum leading rate had significant positive effect on savings mobilization in the short run while inflation rate exerted significant negative effect on savings mobilization contrary to the latter significant positive response to changes in M2-GDP ratio in the short run. The study recommended the need for government to consider a reduction from the current double digit to single digit particularly in nominal interest rate and prime lending rate in order to stimulate savings through investment in Nigeria. Finally, monetary authorities may consider a moderation rise in price level thereby encouraging people to save.
Оптимизация пробоподготовки при определении жирнокислотного состава ультрапастеризованного молока
Authors: Аухадиева Э. А. , Мусабиров Д. Э. , Зеленковская Е. Е. , Курилов М. В. , Усманова Э. Н.
Published: April 2024

С целью удешевления себестоимости молока некоторые недобросовестные производители изготавливают фальсифицированные молочные продукты, потребление которых может привести к нарушениям в питании: человек получает чувство насыщения, но недополучет те макро- и микронутриенты, на которые рассчитывает. Определение жирно-кислотного состава молочной продукции является эффективным методом выявления фальсификации. При ультрапастеризации молоко гомогенизируется под давлением и подвергается обработке при сверхвысокой температуре с последующей асептической упаковкой. Из-за гомогенности ультрапастеризованного молока возникают проблемы с экстракцией жира при проведении хроматографического анализа по определению жирно-кислотного состава. В статье приводятся результаты эксперимента, которые подтверждают, что при предварительном нагревании ультрапастеризованного молока до 45 0С жировая фракция при центрифугировании хорошо разделяется. Для проверки работоспособности методики проведена оценка показателей качества результатов анализа на примере пальмитиновой кислоты, которая показала, что ее метрологические характеристики ниже, чем в базовом нормативном документе (ГОСТ 32915), что позволяет рекомендовать ее к применению на практике.
O USO DE HIDROQUINONA PARA TRATAR MELASMA E SUA RELAÇÃO COM A OCRONOSE EXÓGENA
Authors: Paloma de Souza Araújo Yara , De Lima Barbosa Isabela , Soares da Silva Braga Jessica
Published: April 2024

As hipermelanoses são enfermidades que acometem os tecidos da derme e epiderme e se caracterizam pela capacidade de alteração na pigmentação da pele. Os recorrentes números dessas alterações levaram ao aumento da produção de cosméticos com funções clareadoras. A hidroquinona é um composto fenólico, amplamente utilizado na indústria alimentícia como antioxidante e na indústria cosmética e dermatológica, devido às suas propriedades despigmentantes. No entanto, diversos estudos têm levantado preocupações sobre sua segurança e efeitos adversos, como a ocronose exógena. A ocronose exógena é uma condição dermatológica caracterizada pela hiperpigmentação negro-azulada fuliginosa, localizada na região onde foi aplicado o agente causador, como o uso prolongado e inadequado da hidroquinona. A exposição crônica a altas concentrações dessa substância pode levar ao acúmulo desta nos tecidos, resultando em danos irreversíveis à pele e à cartilagem. Desta forma, ressalta-se a importância do controle referente ao uso sem acompanhamento profissional dessa substância.
JOGO DE DOMINÓ COMO ALTERNATIVA DE ENSINO NA ABORDAGEM DAS QUATRO OPERAÇÕES FUNDAMENTAIS
Authors: Oliveira dos Reis Tharlon , Passos Lima Eusom
Published: April 2024

O estudo da matemática, por meio da alternativa de ensino através dos jogos, é de suma importância para o desenvolvimento do aluno. Além de proporcionar um ambiente de ensino e a aprendizagem, o aluno é capaz de desenvolver maior interesse pela matemática. Sendo assim, esta pesquisa teve como objetivo a elaboração do jogo do dominó como alternativa de ensino para a abordagem das quatro operações fundamentais. O levantamento de dados constituiu na aplicação de um questionário com perguntas objetivas e subjetivas para 20 participantes da pesquisa do 6° ano do Ensino Fundamental de uma rede pública, do Município de Moju-PA, com o propósito de averiguar o conhecimento prévio sobre a temática. Com os dados coletados, foi perceptível que a maioria, (52%) dos participantes, possuíam algum tipo de dificuldade em relação à temática. Portanto, por meio da pesquisa realizada, pôde ser executada com êxito a alternativa de ensino, a fim de facilitar e melhorar o processo de ensino-aprendizagem das quatro operações fundamentais.
AÇÃO POPULAR COM MEDIDA CAUTELAR CONTRA UMA EMPRESA DE SANEAMENTO EM DANO AMBIENTAL: O CASO DE ORLÂNDIA-SP
Authors: Garbin Alvaro , De Souza Lehfeld Lucas
Published: April 2024

Diante do aumento populacional e das atividades econômicas nos grandes centros urbanos, tem-se tornado cada vez mais inviável o Setor Público investir, custear e administrar todo o montante financeiro que envolve a prestação de serviços públicos de abastecimento de água e esgoto sanitário. A solução encontrada tem sido terceirizar a gestão deste tipo de serviço. Isso ocorreu na cidade de Orlândia-SP, onde a Prefeitura Municipal desta referida cidade, em 2020, por meio de uma Concorrência Pública, firmou um contrato de concessão comum para exploração dos serviços públicos de abastecimento de água e de esgotamento sanitário por um período de 35 (trinta e cinco anos). No entanto, devido a constatações de irregularidades praticadas tanto pelo Ente Público como pela Concessionária, houve por bem o ajuizamento de uma Ação Popular para averiguar os fatos e punir os responsáveis. Este artigo tem o objetivo de avaliar a importância da Ação Popular para apurar irregularidades praticadas pelos envolvidos em uma prática de Concessão. Para o desenvolvimento deste trabalho foram realizadas pesquisas bibliográfica e documental, com abordagem qualitativa, sendo os dados analisados pelos métodos dedutivo e indutivo.
Dolor Neuropático (Parte I). Actualización de su Definición, Mecanismos y Diagnóstico
Authors: Brumovsky Pablo R. , González Susana , Vivé Jorge E. , Marchevsky Eduardo D.
Published: April 2024

El diagnóstico adecuado del dolor neuropático ha sido y continúa siendo motivo de intenso debate. De hecho, en la actualidad no existen pruebas contundentes para el diagnóstico de este tipo de dolor; dicho diagnóstico suele ser eminentemente clínico. Más aún, en Argentina aún se carece de guías en el idioma castellano con algoritmos que encaminen hacia soluciones de diagnóstico y tratamiento del dolor neuropático. En la presente revisión, y basándonos en los esfuerzos recientes de la comunidad internacional para la creación de criterios diagnósticos que permitan la correcta identificación de esta patología debilitante, nos hemos propuesto los siguientes objetivos: 1) ofrecer una visión actualizada del dolor neuropático, su definición, manifestaciones clínicas y epidemiología, así como la delineación de sus potenciales mecanismos; 2) sugerir estrategias y criterios que contribuyan a un adecuado diagnóstico de los pacientes con dolor neuropático; 3) facilitar la selección de pacientes para el diseño eficaz de ensayos clínicos, y 4) dar el primer paso para la apertura de nuevos canales de comunicación entre médicos clínicos e investigadores clínicos y básicos dedicados al estudio del dolor.
Mejoría de la Calidad de Vida de Pacientes con Dolor Neuropático Utilizando Monitoreo Ambulatorio Continuo
Authors: Dall’aglio Rocha Carlos Eduardo , Martins Marielza Ismael , Foss Marcos Henrique , Dos Santos Junior Randolfo , Chessa Dias Lilian , Forni José Eduardo , Detoni Michele , Rodrigues Da Cunha Ana Márcia , Da Silva Junior Sebastião Carlos
Published: April 2024

Justificación y Objetivos: El manejo de pacientes con dolor crónico exige un abordaje multifuncional en las áreas física, psicológica, social y ocupacional. El entendimiento de la fisiopatología del dolor y su evaluación optimizan el tratamiento. El objetivo de este estudio fue evaluar en forma exacta los mejores predictores de calidad de vida a través de registros semanales realizados por régimen ambulatorio y domiciliario, verificando actividades prácticas y de la vida diaria.Método: Se utilizaron las siguientes escalas de evaluación: Listado de Dolor de Wisconsin, Gráfico de Humor, cuestionario de Dolor de McGill, Protocolo Post-Sueño y el cuestionario genérico de calidad de vida (Whoqol-bref).Resultados: La actividad física, el desempeño laboral y el patrón de sueño señalaron mejor calidad de vida. La sensibilidad al dolor, evasión al miedo y la dependencia de otra persona son responsables por la cantidad significativa de variación en las actividades propuestas. Estos hallazgos sugieren que las fuentes externas de orientación, además de las internas como evitar el miedo al dolor, pueden servir para influir en el comportamiento físico y social.Conclusión: El dolor crónico neuropático debe ser evaluado en sus particularidades de presentación clínica, comportamental y social, pues tales elementos son fundamentales para una buena evolución.
Estimulación de la Médula Espinal Versus Tratamiento Médico Convencional para el Dolor Neuropático: Un Ensayo Multicéntrico Randomizado Controlado en Pacientes con Síndrome de Cirugía Fallida de Columna
Authors: Kumar Krishna , Taylor Rod S. , Jacques Line , Eldabe Sam , Meglio Mario , Molet Joan , Thomson Simon , O’callaghan Jim , Eisenberg Elon , Milbouw Germain , Buchser Eric , Fortini Gianpaolo , Richardson Jonathan , North Richard B.
Published: April 2024

Los pacientes con dolor neuropático secundario al síndrome de cirugía fallida de columna (SCFC) típicamente experimentan dolor persistente, discapacidad, y reducción de la calidad de vida. Planteamos la hipótesis de que la estimulación medular (EM) es una terapia efectiva sumada al tratamiento médico convencional (TMC) para esta población de pacientes. Hemos randomizado a 100 pacientes con SCFC con dolor predominante en el miembro inferior de origen neuropático radicular para que reciban estimulación medular más tratamiento médico convencional (grupo EM) o solamente tratamiento médico convencional (grupo TMC) durante por lo menos 6 meses. El resultado primario fue la proporción de pacientes que logró un 50% o más de alivio del dolor en el miembro inferior. Los resultados secundarios fueron la mejoría en el dolor de espalda y miembro inferior, calidad de vida relacionada a la salud, capacidad funcional, uso de medicamentos y tratamiento no farmacológico para el dolor, nivel de satisfacción del paciente, e incidencia de complicaciones y efectos adversos. Se permitió el cruzamiento luego de la visita a los 6 meses, y todos los pacientes fueron seguidos durante un año. En el análisis de intención de tratamiento a los 6 meses, 24 pacientes EM (48%) y 4 pacientes TMC (9%) (p < 0.001) lograron el resultado primario. En comparación con el grupo TMC, el grupo EM experimentó una mejoría del alivio del dolor de miembro inferior y espalda, calidad de vida, y capacidad funcional, así como también una mayor satisfacción con el tratamiento (p ≤ 0.05 en todas las comparaciones). Entre los 6 y 12 meses, 5 pacientes de EM pasaron a TMC, y 32 pacientes de TMC pasaron a EM. A los 12 meses, 27 pacientes de EM (32%) experimentaron complicaciones relacionadas al dispositivo. En pacientes selectos con SCFC, la EM provee un mejor alivio del dolor y mejora la calidad de vida relacionada a la salud y la capacidad funcional en comparación con el TMC solo.
Creación del Programa Provincial de Neuromodulación: Una necesidad actual y una proyección al futuro
Authors: Collia Alejandro Federico
Published: April 2024

Por primera vez en la historia de la medicina mundial, un organismo estatal reconocerá la cobertura médica para pacientes sin recursos que requieran ser tratados bajo la terapia de neuromodulación. Para ello, la creación del Programa Provincial de Neuromodulación permitirá optimizar los recursos ya existentes, estipular una correcta selección de pacientes y estimular la difusión y entrenamiento de profesionales involucrados. Las técnicas de neuromodulación son procedimientos de alta complejidad y costo que se emplean de manera creciente en todo el mundo para el tratamiento de múltiples enfermedades refractarias a otros tratamientos (Parkinson, espasticidad, trastornos motores, epilepsia, dolor crónico no oncológico, etc). No obstante, pese a sus innegables beneficios, sus indicaciones se encuentran en evolución y cambian a medida que la experiencia se acumula y la tecnología evoluciona.
Local Government Cadres Guiding Tourism Economic Development:from the Perspective of Flow Economy
Authors:   Institute of Higher Education, QI Xiufang
Published: April 2024

In the past two or three years, a group of cultural and tourism directors represented by He Jiaolong in Zhaosu, Yili, Xinjiang, Liu Hong and Jiang Zeduoji in Ganzi Prefecture, Sichuan, Xie Wei in Suizhou City, Hubei, and Wu Jiaojiao in Dafang County, Guizhou, have relied on short video platforms such as Douyin and Kuaishou to made their own small videos promoting their hometowns, and have become popular on the Internet one after another. These web celebrity directors have promoted the tourism economy of their hometown through continuous publicity, live broadcasting with goods and other forms, and contributed great strength to the development of their hometown. Their success, attracted around the Secretary of Culture and Tourism have followed suit, in the country set off a wave of Secretary for hometown tourism endorsement boom. As a netizen, the author has also learned about this hot event. Through reviewing a large amount of data, using literature research, case analysis and other research methods, the author has carried out some of his own research on the phenomenon of network red bureau chiefs􀆳tourism in various places from the perspective of traffic economy. The study found that: First, in the context of the global digital economy, short video platforms based on algorithms and big data are profoundly changing the lives of ordinary people; Second, the emergence of the secretary of Internet Celebrity has brought a new development model of flow economy and has become a booster for the development of local tourism; Third, the culture and tourism secretary of Internet Celebrity has a unique value for local development in the cultural, political and economic fields. This study also found that the􀆳Internet celebrity culture and tourism director model has been copied in large numbers in various places. This phenomenon should be paid attention to and guided. Relevant departments should make efforts to improve their governance ability and tourism industry management ability, so that the Internet celebrity hit sites can be sustained, not just a simple imitation.