bluuebunny/crossref_metadata_2025 huggingface dataset:
Changing landscape of liver transplant in the United States—time for a new innovative way to define and utilize the “non-standard liver allograft”—a proposal
Authors: Seth Rashmi , Andreoni Kenneth A.
Published: August 2024

Since the first liver transplant was performed over six decades ago, the landscape of liver transplantation in the US has seen dramatic evolution. Numerous advancements in perioperative and operative techniques have resulted in major improvements in graft and patient survival rates. Despite the increase in transplants performed over the years, the waitlist mortality rate continues to remain high. The obesity epidemic and the resultant metabolic sequelae continue to result in more marginal donors and challenging recipients. In this review, we aim to highlight the changing characteristics of liver transplant recipients and liver allograft donors. We focus on issues relevant in successfully transplanting a high model for end stage liver disease recipient. We provide insights into the current use of terms and definitions utilized to discuss marginal allografts, discuss the need to look into more consistent ways to describe these organs and propose two new concepts we coin as “Liver Allograft Variables” (LAV) and “Liver Allograft Composite Score” (LACS) for this. We discuss the development of spectrum of risk indexes as a dynamic tool to characterize an allograft in real time. We believe that this concept has the potential to optimize the way we allocate, utilize and transplant livers across the US.
The Oral and Maxillofacial Pathologist: The Dentist Behind the Microscope
Authors: Battistelli Luisa Souza , Santos Thaís Aguiar , Anbinder Ana Lia
Published: August 2024

Lots of people think that all dentists use little mirrors and loud tools like dental drills, but there is a type of dentist who does not need these things: the oral and maxillofacial pathologist. Can you believe that oral pathologists do not actually treat the teeth or even meet the patient? The oral pathologist receives a tiny piece of tissue from the patient, usually obtained through a small surgery called a biopsy. Then, a super tiny slice of that tissue is prepared and placed on a glass slide, and the oral pathologist looks at it through a microscope to figure out what disease the patient might have. This information is important to give the patient the right treatment. Do you want to learn more about this process and about the healthcare professional who does not meet the patient face-to-face? Keep reading to find out all these answers and more!
Embodying two shores of the Mediterranean Sea: the liminal masculinity of minors migrating alone to Spain
Authors: Alonso Bakea , Longo Valentina , Ruiz Garriga Álvaro
Published: August 2024

The article aims to provide an analysis based on the practical experience of social intervention in violence prevention with migrant minors arriving alone in Spain. In order to offer keys and recommendations, and based on situated knowledge, we provide insights on how to approach the intervention framework from a methodological point of view using liminal spaces as border and transition places that need to be named and taken into consideration for a transformative work. Different metaphorical borders, characterized by tension and potential change, are analyzed from a gender and intersectional perspective. We discuss the Law-border and the tension between protection they receive as minors and exclusion/politics of suspicion they receive as migrants. The Age-border (children/men) is discussed taking into account the different gender regimes they cross. The Color-border: here issues of racism and colonialism are considered. Finally, we discuss the Masculinity-border and the tension between reception and the reproduction of violence. We use the concept of liminal masculinities as a specific state or form that subordinate or marginalized masculinity adopts in migrant minors, suspended legally, functionally, and biographically, among others borders.
Enhanced boxing punch impact with silicone cushioning
Authors: Punthipayanon Sirichet , Kwanboonchan Supranee , Rachanavy Pornthep , Kuo Chia-Hua
Published: August 2024

Introduction

Elastic cushioning materials protect human tissue from injury by absorbing impact energy and delaying its transfer. However, the potential compromise in force delivery to the hitting target remains unknown.

Methods

To examine if silicone cushioning compromises punch force delivery to a hitting target, a double-blind crossover trial with 12 elite boxers was conducted following material tests. Each boxer delivered five maximal punches under two conditions: silicone-hand wrapping and gauze-hand wrapping, in counterbalanced order, with a 3-day interval between sessions. Force distribution along the Z-axis indicated the punch's intended direction, while forces along the X and Y axes represented force dissipation toward unwanted direction.

Results

The material tests (based on ASTM International, West Conshohocken, PA, USA) demonstrated substantially higher compression to disruption for silicone than gauze of similar thickness. During the punching trials, the silicon-based hand wrapping exhibited slightly higher total force production (436 ± 33 N vs. 372 ± 12 N, p < 0.001) than the gauze-based hand wrapping. Moreover, force wastage, calculated as the sum of forces along the X and Y axes vs. the total force produced in percentage, was notably lower for silicone material (2.0% wastage) compared to gauze (3.8% wastage) (p < 0.001). The use of silicone materials lengthened the contact time between the punching fist and the hitting target from 35 ms to 50 ms (p < 0.001).

Conclusion

The elastic cushion does not compromise the force delivery of the boxing glove to the hitting target. Instead, it appears to allow for additional maneuvering time for alignment during the fist-target contact with higher impact.
Cross-sectional association between frequency of vigorous physical activity and academic achievement in 214,808 adolescents
Authors: Zhang Xiaohui , Zhang Danqing , Yang Xingyi , Chen Sitong
Published: August 2024

Background

This study explores the intricate link between vigorous physical activity and academic achievement in adolescents. By analyzing data from the Health Behaviour in School-aged Children (HBSC) survey, it seeks to understand how engaging in high-intensity physical activities influences academic achievement.

Methods

A comprehensive cross-sectional analysis was conducted on a vast dataset comprising 214,808 adolescents aged 11, 13, and 15 years. The frequency of vigorous physical activity was determined through self-reports, while academic achievement was assessed based on students’ self-perceptions, reflecting their understanding of teachers’ evaluations of their academic performance.

Results

Adolescents who reported engaging in vigorous physical activity daily were more likely to report higher academic achievement. This positive correlation was consistent across various demographic groups, including different age cohorts and both genders, indicating a universal benefit of regular vigorous physical activity on perceived academic success.

Conclusion

The findings of this study underscore the significant role that regular vigorous physical activity plays in the academic lives of adolescents. The correlation between daily vigorous physical activity and enhanced self-reported academic achievement suggests that encouraging high-intensity physical activities in schools could be a key strategy in boosting educational outcomes.
Inter-individual variability in peripheral oxygen saturation and repeated sprint performance in hypoxia: an observational study of highly-trained subjects
Authors: Takei Naoya , Muraki Ryuji , Girard Olivier , Hatta Hideo
Published: August 2024

Individual variations in peripheral oxygen saturation (SpO2) during repeated sprints in hypoxia and their impact on exercise performance remain unclear despite fixed external hypoxic stimuli (inspired oxygen fraction: FiO2). This study examined SpO2 individual variations during repeated sprints in hypoxia and their impact on exercise performance. Thirteen highly-trained sprint runners performed 10 × 10-s cycle sprints with 30-s passive recoveries in normobaric hypoxia (FiO2: 0.150). Mean power output (MPO), post-sprint SpO2, and heart rate for each sprint were assessed. Sprint decrement score (Sdec), evaluating fatigue development, was calculated using MPO variables. Participants were categorized into a high saturation group (HiSat, n = 7) or a low saturation group (LowSat, n = 6) based on their mean post-sprint SpO2 (measured 10–15 s after each sprint). Individual mean post-sprint SpO2 ranged from 91.6% to 82.2%. Mean post-sprint SpO2 was significantly higher (P < 0.001, d = 1.54) in HiSat (89.1% ± 1.5%) than LowSat (84.7% ± 1.6%). A significantly larger decrease in Sdec (P = 0.008, d = 1.68) occurred in LowSat (−22.3% ± 2.3%) compared to HiSat (−17.9% ± 2.5%). MPO (P = 0.342 d = 0.55) and heart rate (P = 0.225 d = 0.67) did not differ between groups. There was a significant correlation (r = 0.61; P = 0.028) between SpO2 and Sdec. In highly-trained sprint runners, individual responses to hypoxia varied widely and significantly affected repeated sprint ability, with greater decreases in SpO2 associated with larger performance alterations (i.e., larger decrease in Sdec).
Do agricultural credit, wheat, and rice production impact environmental quality? Novel evidence from China’s mega agricultural regions
Authors: Ahmad Muhammad Irshad , Shen Qiong , Zhang Ying , Rehman Abdul , Song Chunxiao , Ma Hengyun
Published: August 2024

Gaining a comprehensive understanding of the carbon emissions cycle in the atmosphere resulting from agricultural activities is crucial for assessing its influence on environmental quality. This study used panel datasets covering the period from 1990–2022 to investigate the influence of wheat and rice production on environmental quality in the six mega agricultural provinces of China namely Anhui, Hebei, Hubei, Henan, Jiangsu, and Sichuan. Study employed several econometric approaches such as Cross-Sectional Dependency tests, unit root and cointegration tests, Panel Mean Group Autoregressive Distributed Lag (PMG-ARDL), Panel Quantile (PQ) and Panel Least Square (PLS) regression analysis for the robustness of the findings. The empirical findings of PMG-ARDL model reveal that rice production positively increases CO2 emissions in the long run. The variables fertilizers usage, agricultural water consumption and agricultural credit also have positive impact on CO2 emission in the long run. Further, short-term results reveal that all the concerned variables positively contribute to increase the CO2 emissions. The PQR results illustrate that rice and wheat production, fertilizer consumption, agricultural water usage, agricultural credit and agricultural GDP have positive and significant impact on CO2 emission across the quantiles. Additionally, PLS outcomes show positive and significant association between wheat productivity, agricultural credit, fertilizer and agricultural GDP on CO2 emissions. The Dumitrescu and Hurlin (D–H) panel causality show unidirectional association among: carbon emission → pesticides use, carbon emission → temperature, and carbon emission → agricultural GDP. A significant bidirectional causal association was found between: carbon emission ↔ rice production, carbon emission ↔ wheat production, carbon emission ↔ fertilizers use, carbon emission ↔ agricultural water use, and carbon emission ↔ agricultural credit. These findings contribute to the understanding of the drivers of CO2 emissions in agriculture and provide valuable insights for policymakers aiming to mitigate environmental impacts while promoting sustainable agriculture, resilience, financial support to encourage green technology and implement robust monitoring mechanisms to protect quality of environment and agricultural sustainability.
Analysis of therapeutic effects of congenital kyphosis in children due to anterior vertebral bone bridges
Authors: Xu Ke , Zhang Cefei , Xia Bing , Zhao Yufeng , Jiang Xiaowei , Li Chonghao , Hu Weiming , Liu Fuyun
Published: August 2024

Objective

To investigate the choice of treatment options and long-term orthopedic results of congenital kyphosis in children due to anterior vertebral bone bridges.

Methods

The clinical data of children with congenital kyphosis due to anterior vertebral bridges treated at our center from May 2005 to May 2020 were retrospectively analyzed. We evaluated the clinical features of the deformity, the choice of treatment plan, the change in the Cobb angle of the kyphosis and the improvement of the sagittal trunk deviation before and after treatment and at the final follow-up visit by means of pre-treatment and post-treatment imaging, physical examination and analysis of the case data.

Results

A total of 35 children were included. Clinical follow-up was conducted on a cohort of 5 children, all of whom presented with type Ⅱ congenital kyphosis caused by less than three thoracic anterior bone bridges. The study findings revealed no noteworthy advancement in segmental kyphosis, thoracic kyphosis, lumbar lordosis, and sagittal vertical axis during the final follow-up assessment (p > 0.05). In a cohort of 30 pediatric patients who underwent surgical intervention, segmental kyphosis was corrected, with a decrease from an average angle of (40.1 ± 20.5)° to (15.6 ± 9.5)°. Furthermore, significant improvements were noted in segmental kyphosis, thoracic kyphosis, lumbar lordosis, and sagittal vertical axis at the postoperative stage compared to the preoperative stage (p < 0.05). Notably, improvements in thoracic kyphosis and lumbar lordosis persisted at the final follow-up visit compared to postoperative (p < 0.05).

Conclusion

Type Ⅱ congenital kyphosis in children caused by anterior bony bridges of less than three vertebrae in the thoracic segment can be followed up for a long period, and type Ⅱ/Ⅲ congenital kyphosis caused by anterior bony bridges of the vertebrae in the thoracolumbar, lumbar, and lumbosacral segments requires early surgery.
Hemodynamic changes for half cover left subclavian artery ostium during thoracic endovascular aortic repair
Authors: Li Xiaowei , Yuan Xiaoming , Wen Zan , An Minghua , Bi Wei
Published: August 2024

Purpose

Some clinicians use endografts to cover half the left subclavian artery (LSA) ostium to cure some cases with insufficient proximal landing zone (PLZ) in thoracic endovascular aortic repair (TEVAR) treatment. We used computational fluid dynamics (CFD) to study the hemodynamic changes in the LSA because they may cause acute thrombosis or arteriosclerosis.

Methods

The digital model of the aortic arch was established and named model A, which only included the supraarch branch of the LSA. By directly covering half of the LSA ostium, which was named as model B. All established models were imported into the Gambit grid division software for grid division and were subsequently imported into the Fluent software for hemodynamic numerical simulation and calculation to analyze the related changes in LSA hemodynamic parameters after stent implantation.

Results

Under the same aortic inlet flow, in model B, the local blood flow velocity of the LSA ostium increased and the whole blood flow velocity at the distal end decreased. The average wall shear stress (WSS) of the LSA was significantly decreased. Meanwhile there was an obvious turbulent flow in the LSA lumen, and the related blood flow state was disordered.

Conclusion

CFD research confirmed that the implantation of an endograft covering half the LSA ostium can cause obvious hemodynamic changes, which is likely to cause a long-term arteriosclerosis or acute thrombosis of the LSA, finally increasing the risk of stroke. Once this operation is performed in some specific clinical cases for simplicity and economy, it seems that we should actively antiplatelet and follow up regularly.
Left distal sciatic giant solitary myxoid neurofibroma: a case report & literature review
Authors: Thawabtah Fatima az-Zahra’ , Idkedek Mayar , Nimer Hafez
Published: August 2024

Introduction

Neurofibroma, a rare benign tumor of the peripheral nervous system, can manifest anywhere along a nerve from the dorsal ganglion to its terminal branches. Myxoid neurofibroma can present as a solitary non-tender nodule and is often confirmed by positive immunohistochemical staining for S-100 protein. However, in 50% of cases, neurofibromas are associated with neurofibromatosis.

Case presentation

We present a case of a 34-year-old male with mild pain in the posterior part of his left thigh, accompanied by a slowly-growing swelling particularly noticeable when flexing his knee. It had gradually increased in size over several months, which the patient observed as a decrease in the degree of knee extension. Initial biopsy indicated schwannoma with no evidence of malignancy. Four years later, the swelling increased in size and necessitated resection surgery, revealing an irregular giant tumor measuring 8 *6 *4.5 cm, adherent to adjacent structures, including the femur, muscles, popliteal artery and vein, and a branch of the sciatic nerve. Pathological analysis reclassified the diagnosis to low-grade myxoid neurofibroma. Follow-up MRI three months later showed gross total resection without residual or recurrence of the tumor.

Discussion

Solitary neurofibromas are often small in size, ranging from 1 to 2 cm in the greatest dimension. Alternatively, tumors that occur as a part of genetic neurofibromatosis tend to be multiple and often grow to large sizes. In our case, the patient didn't have neurofibromatosis as he didn't meet its diagnostic criteria despite having a giant tumor measuring approximately 8*6*4.5 cm. To our knowledge, this is the first report of giant myxoid solitary neurofibroma of the thigh apart from neurofibromatosis. Thus, this type of tumor should be considered in the differential diagnosis of tumors at this location.
Evaluation of intrapulmonary arteriovenous anastomoses before and after oxygen supplementation, using transthoracic agitated saline contrast echocardiography in rescued Korean raccoon dogs
Authors: Lee Chang-eun , Kim Myeongsu , Han Jae-Ik , Lee Kichang , Yoon Hakyoung
Published: August 2024

Introduction

Intrapulmonary arteriovenous anastomoses (IPAVAs) are defined as relatively large, dynamic shunt vessels that connect the pulmonary arterial and venous systems, thereby bypassing the pulmonary capillary system. IPAVAs lower elevated pulmonary arterial pressure; however, the presence of the shunt can result in impaired pulmonary gas exchange and paradoxical embolism. Furthermore, the prevalence and effects of IPAVAs in raccoon dogs remain unknown. This study aimed to determine the prevalence of IPAVA among rescued Korean raccoon dogs and evaluate the changes in IPAVA following oxygen supplementation.

Methods

Nineteen raccoon dogs rescued by the Jeonbuk Wildlife Centre between August 2022 and December 2023 were subjected to echocardiography. Sixteen healthy and three abnormal raccoon dogs were subjected to transthoracic agitated saline contrast echocardiography (bubble study) based on the echocardiography results. IPAVA was considered to be present if the left heart contrast was visualised after four cardiac cycles following the visualisation of the first right heart contrast. Bubble scores (BS0–5) were assigned based on the maximum number of microbubbles observed in the left ventricular lumen per frame of the ultrasound image. BS was assigned before and after supplementation with 100% oxygen for 5 min.

Results

IPAVA was detected in 12 of the 16 healthy raccoon dogs at rest (75%). The BS of the 15 IPAVA-positive raccoon dogs ranged from 1 to 4 points (BS1, 1; BS2, 4; BS3, 8; and BS4, 2). Blood flow through the IPAVA (QIPAVA) was reduced or absent in the 15 IPAVA-positive raccoon dogs after supplementation with 100% oxygen (BS0, 11; BS2, 4). Moreover, BS of the IPAVA showed a significant correlation with the cardiac output per body weight (BW).

Conclusion

The prevalence of IPAVA in healthy raccoon dogs at rest was 75%. Adequate oxygen supplementation was found to be effective in reducing QIPAVA, which may help prevent potential negative factors such as pulmonary gas exchange impairments and paradoxical embolism that can occur with IPAVA.
Age-dependent variations in proteomic characteristics of spermatozoa in Simmental bull
Authors: Satrio Faisal Amri , Karja Ni Wayan Kurniani , Setiadi Mohamad Agus , Kaiin Ekayanti Mulyawati , Pardede Berlin Pandapotan , Purwantara Bambang
Published: August 2024

Increasing the age of bulls results in a decrease in reproductive function, including a reduction in sperm quality, which plays a vital role in determining the fertility of bulls. Through a proteomic approach, this research aims to analyze the influence of age factors on various proteomes contained in bull sperm. Frozen semen samples from Simmental Bulls were categorized into three age groups: two, four, and ≥10 years old. Subsequently, the post-thaw sperm cells obtained were separated based on molecular weight using 1D-SDS-PAGE. Peptides extracted from the bands produced in each age group were subjected to LC-MS/MS analysis. A total of 72 protein types were identified, with 45 being detected in the 4-year-old group and 41 expressed in both the 2 and ≥10-year-old groups. The results provided insights into proteins' role in sperm metabolism across all age groups. Specifically, the 2-year-old group exhibited the expression of proteins associated with acrosome assembly and spermatid development (SPACA1). In contrast, those in the 4-year-old group were linked to motility (PEBP4) and sperm decapacitation factor (PEBP1). Proteins expressed in the 2 and -year-old groups were discovered to be involved in fertilization processes (TEX101). In contrast, the ≥10-year-old age group was associated with hyperactive movement related to capacitation (Tubulin). In conclusion, age influenced the differences observed in the proteomic profile of post-thaw Simmental bull sperm using the 1D-SDS-PAGE tandem LC-MS/MS approach.
Genetic variation and recombination analysis of the GP5 gene of the porcine reproductive and respiratory syndrome virus in Thailand
Authors: Zheng Yajie , Li Gan , Liu Kexin , Luo Qin , Sun Wenchao , Zhao Mengmeng
Published: August 2024

Introduction

Porcine reproductive and respiratory syndrome (PRRS) is a significant threat to the global swine industry, and its prevalence in Thailand spans over two decades.

Methods

To understand the genetic variation and recombination of the PRRS virus (PRRSV) GP5 gene in Thailand, we retrieved 726 GP5 gene sequences from the NCBI database. Phylogenetic trees were constructed using the neighbor-joining (NJ) and maximum likelihood (ML) methods, and recombination analysis was performed.

Results

Homology analysis was conducted on 83 PRRSV-1 and 83 PRRSV-2 strains. Phylogenetic analysis revealed the prevalence of both PRRSV-1 and PRRSV-2 strains in Thailand, with the latter exhibiting wider distribution. PRRSV-1 strains clustered into clades A, D, and H, while PRRSV-2 strains grouped into lineages 1, 5, and sublineage 8.7, further divided into 8.7/HP and 8.7/NA sublineages. Sublineage 8.7/NA strains accounted for a significant proportion of circulating PRRSV-2 strains. Homology analysis showed nucleotide and amino acid similarities ranging from 75.4 to 100.0% and 41.3 to 100.0% for PRRSV-1, and 78.6 to 100.0% and 70.8 to 100.0% for PRRSV-2 strains. Amino acid sequence alignments revealed mutations, insertions, and deletions in PRRSV-1 GP5, and key residue mutations in PRRSV-2 GP5 associated with biological functions. Recombination analysis identified two recombination events within PRRSV-2 sublineage 8.7 strains.

Discussion

These findings confirm the variability of the GP5 protein. This study enhances our understanding of PRRSV prevalence and genetic variation in Thailand, contributing valuable insights for PRRS prevention and control.
Case report: Giant cell tumor of bone in the mandible of a goat—diagnostics, surgical treatment, and outcome
Authors: Biermann Nora M. , Piechl Susanna , Dinhopl Nora , Fuchs-Baumgartinger Andrea , Weissenbacher-Lang Christiane , Bertram Christof A.
Published: August 2024

Neoplastic processes of the mandible and their treatment are rarely reported in large animal species. Specifically, giant cell tumor of bone is an uncommon tumor in animals and has been associated in humans with locally invasive behavior and a high recurrence rate. En-bloc resection is the treatment of choice, but depending on the localization of the tumor, this may result in functional deficits. This report details the diagnostic work-up, treatment, and long-term outcome of a giant cell tumor of bone involving the rostral mandible and mandibular symphysis of a goat. Extensive rostral mandibulectomy involving the entire mandibular symphysis without surgical fixation of the hemimandibles was performed. Histological and electron microscopic findings of the tumor were consistent with a giant cell tumor of bone. Although a mutation of the H3F3A gene is considered the driver of tumor development in human giant cell tumors, using molecular analysis, this gene mutation could not be confirmed in this case. Follow-up examinations revealed spontaneous secondary fusion of both hemimandibles and no signs of tumor recurrence. Nearly 1 year after surgery, the owners reported no signs of tumor regrowth.
Optimization Design of Magnetically Suspended Control and Sensitive Gyroscope Deflection Channel Controller Based on Neural Network Inverse System
Authors: Chen Feiyu , Wang Weijie , Yu Chunmiao , Wang Shengjun , Zhang Weian
Published: August 2024

To meet the strong coupling characteristics of the MSCSG deflection channel and the demand for high control accuracy, a two-degree-of-freedom deflection channel model is firstly established for the structure and working principle of the MSCSG; to meet the strong coupling between the two channels, the inverse system method is used to decouple the model; then, the operation principle of the MSCSG system is introduced, and the modeling of the power amplifier is carried out; to meet the demand for high-precision control of the MSCSG rotor system, the RBF neural network is improved using the fuzzy method to achieve high-precision estimation of the residual coupling terms and deterministic disturbances, and the adaptive sliding mode controller is designed. For the high-precision control of the MSCSG rotor system, the fuzzy method is used to improve the RBF neural network to realize the high-precision estimation of the residual coupling term and uncertain perturbation, and the adaptive sliding mode controller is designed, and the convergence of the controller is proved on the basis of the Lyapunov stability criterion. Simulation analysis shows that the method has a large improvement in decoupling performance and anti-disturbance performance compared with the traditional method, and finally, the experiment verifies the effectiveness of the present method and achieves the optimization of the deflection channel controller. The method can be extended to other magnetic levitation actuators and related fields.
A New Variable-Stiffness Body Weight Support System Driven by Two Active Closed-Loop Controlled Drives
Authors: Li Xiao , Zhong Jizheng , An Songyang , Huang Yizhe
Published: August 2024

Body weight support (BWS) systems are crucial in gait rehabilitation for individuals incapacitated due to injuries or medical conditions. Traditional BWS systems typically employ either static mass–rope or dynamic mass–spring–damper configurations, which can result in inadequate support stiffness, thereby leading to compromised gait training. Additionally, these systems often lack the flexibility for easy customization of stiffness, which is vital for personalized rehabilitation treatments. A novel BWS system with online variable stiffness is introduced in this study. This system incorporates a drive mechanism governed by admittance control that dynamically adjusts the stiffness by modulating the tension of a rope wrapped around a drum. An automated control algorithm is integrated to manage a smart anti-gravity dynamic suspension system, which ensures consistent and precise weight unloading adjustments throughout rehabilitation sessions. Walking experiments were performed to evaluate the displacement and load variations within the suspension ropes, thereby validating the variable-stiffness capability of the system. The findings suggest that the online variable-stiffness BWS system can reliably alter the stiffness levels and that it exhibits robust performance, significantly enhancing the effectiveness of gait rehabilitation. The newly developed BWS system represents a significant advancement in personalized gait rehabilitation, offering real-time stiffness adjustments and ongoing weight support customization. It ensures dependable control and robust operation, marking a significant step forward in tailored therapeutic interventions for gait rehabilitation.
Using Longitudinal Trajectories of Working Hours to Search for Quiet Quitters: Characterizing Their Imprints
Authors: Rodwell John
Published: August 2024

The aim of this study is to provide an academic basis for understanding the phenomenon of quiet quitters and begin to detail the characteristics that distinguish them. The defining behavioural characteristic of quiet quitters is that they reduced the hours they worked over time, especially over the pandemic period. A sample of more than 2500 employees in Australia who had been working full-time toward the end of 2019, before the pandemic, and working full-time toward the end of 2022, after many pandemic constraints had been lifted, was analysed using multinomial regression. There were many variables that distinguished between the trajectories of hours worked between 2019 and 2022. Two groups of employees had dramatically or substantially reduced their working hours and displayed nuances in their characterisation, suggesting that they were quiet quitters. The quiet quitters appear to have experienced powerful imprinting during the time of pandemic constraints, and that imprinting may be working against prior occupational norms. The group most like prototypical quiet quitters are likely to leave their job soon, and many of them are confident they will find a job at least as good as the one they now have, with more flexibility. Having a group of employees with a new approach to work may require revisiting many approaches to management.
A Multi-Objective Dynamic Mission-Scheduling Algorithm Considering Perturbations for Earth Observation Satellites
Authors: Li Hai , Li Yongjun , Liu Yuanhao , Zhang Kai , Li Xin , Li Yu , Zhao Shanghong
Published: August 2024

The number of real-time dynamic satellite observation missions has been rapidly increasing recently, while little attention has been paid to the dynamic mission-scheduling problem. It is crucial to reduce perturbations to the initial scheduling plan for the dynamic mission-scheduling as the perturbations have a significant impact on the stability of the Earth observation satellites (EOSs). In this paper, we focus on the EOS dynamic mission-scheduling problem, where the observation profit and perturbation are considered simultaneously. A multi-objective dynamic mission-scheduling mathematical model is first formulated. Then, we propose a multi-objective dynamic mission-scheduling algorithm (MODMSA) based on the improved Strength Pareto Evolutionary Algorithm (SPEA2). In the MODMSA, a novel two-stage individual representation, a minimum perturbation random initialization, multi-point crossover, and greedy mutation are designed to expand the search scope and improve the search efficiency. In addition, a profit-oriented local search algorithm is introduced into the SPEA2 to improve the convergence speed. Furthermore, an adaptive perturbation control strategy is adopted to improve the diversity of non−dominated solutions. Extensive experiments are conducted to evaluate the performance of the MODMSA. The simulation results show that the MODMSA outperforms other comparison algorithms in terms of solution quality and diversity, which demonstrates that the MODMSA is promising for practical EOS systems.
The Impact of Maize Legume Intercropping on Energy Indices and GHG Emissions as a Result of Climate Change
Authors: Romaneckas Kęstutis , Švereikaitė Austėja , Kimbirauskienė Rasa , Sinkevičienė Aušra , Adamavičienė Aida , Jasinskas Algirdas
Published: August 2024

Multicropping can solve energy use and GHG balance problems, but the emergence, development, and productivity of such mixed crops are at risk due to the uneven distribution of precipitation. For this reason, investigations were performed at the Experimental Station of Vytautas Magnus University, Lithuania. Single maize crops were compared with Crimson/red clover, Persian clover, and alfalfa intercropped maize. The objective of this study was to evaluate the main energy indices and GHG balance of legume intercropped maize cultivated in humid and arid vegetative conditions. The results showed that, under arid conditions, the quantity of intercrop biomass was about four times lower than that under humid conditions. Humid conditions were less suitable for maize and resulted in about 3–5 t ha−1 less dried biomass from intercrops and about 6 t ha−1 less biomass in single crops than in arid conditions. Due to the higher yield of maize biomass in the arid season, better energy indicators of crops were obtained in arid than humid conditions. The difference between net energy was about 122–123 MJ ha−1 in all treatments, except for the maize crop with intercropped alfalfa, where the difference was 62 MJ ha−1. All tested technologies were environmentally friendly; the CO2 equivalent varied between treatments from 804 to 884 kg ha−1. The uneven distribution of precipitation during the vegetative season provides insight into the improvement of intercropping technologies. Sowing intercrops at the same time as maize could improve their germination but increase the problem of weed spread.
Precision Breeding and Consumer Safety: A Review of Regulations for UK Markets
Authors: Freeland Laura V. , Phillips Dylan W. , Jones Huw D.
Published: August 2024

Gene-edited crops and livestock have the potential to transform food systems by providing resilience to climate change, pest and disease resistance, and the enhancement of nutrients in feed and food in a time-efficient and precise way. In 2023, the UK Parliament passed the Genetic Technology (Precision Breeding) Bill, paving the way for gene-edited products to be farmed in England and sold, providing they could have theoretically been produced via traditional breeding. In this paper, we describe the possible risks of gene-edited products for consumption using four case studies of gene-edited organisms: increased vitamin D tomatoes, reduced linoleic acid cottonseed oil, porcine reproductive and respiratory virus (PRRSV) resistant pigs and reduced-asparagine wheat. Assuming that the only requirement for an organism to be a Precision-Bred Organism (PBO) is that no transgenic material remains within the organism and that the edit could have, in theory, occurred spontaneously or through traditional breeding methods, then all our case studies would likely be defined as PBOs. We also conclude that the food safety risks of these products appear to be similar to those that society accepts in traditionally bred organisms used for food and feed. However, PBOs that possess markedly altered nutrient profiles may require a dedicated identity-preserved retail chain and/or labelling to avoid unintended over-consumption.
Early Monitoring of Maize Northern Leaf Blight Using Vegetation Indices and Plant Traits from Multiangle Hyperspectral Data
Authors: Guo Anting , Huang Wenjiang , Wang Kun , Qian Binxiang , Cheng Xiangzhe
Published: August 2024

Maize northern leaf blight (MNLB), characterized by a bottom-up progression, is a prevalent and damaging disease affecting maize growth. Early monitoring is crucial for timely interventions, thus mitigating yield losses. Hyperspectral remote sensing technology is an effective means of early crop disease monitoring. However, traditional single-angle vertical hyperspectral remote sensing methods face challenges in monitoring early MNLB in the lower part of maize canopy due to obstruction by upper canopy leaves. Therefore, we propose a multiangle hyperspectral remote sensing method for early MNLB monitoring. From multiangle hyperspectral data (−60° to 60°), we extracted and selected vegetation indices (VIs) and plant traits (PTs) that show significant differences between healthy and diseased maize samples. Our findings indicate that besides structural PTs (LAI and FIDF), other PTs like Cab, Car, Anth, Cw, Cp, and CBC show strong disease discrimination capabilities. Using these selected features, we developed a disease monitoring model with the random forest (RF) algorithm, integrating VIs and PTs (PTVI-RF). The results showed that PTVI-RF outperformed models based solely on VIs or PTs. For instance, the overall accuracy (OA) of the PTVI-RF model at 0° was 80%, which was 4% and 6% higher than models relying solely on VIs and PTs, respectively. Additionally, we explored the impact of viewing angles on model accuracy. The results show that compared to the accuracy at the nadir angle (0°), higher accuracy is obtained at smaller off-nadir angles (±10° to ±30°), while lower accuracy is obtained at larger angles (±40° to ±60°). Specifically, the OA of the PTVI-RF model ranges from 80% to 88% and the Kappa ranges from 0.6 to 0.76 at ±10° to ±30°, with the highest accuracy at −10° (OA = 88%, Kappa = 0.76). In contrast, the OA ranges from 72% to 80% and the Kappa ranges from 0.44 to 0.6 at ±40° to ±60°. In conclusion, this research demonstrates that PTVI-RF, constructed by fusing VIs and PTs extracted from multiangle hyperspectral data, can effectively monitor early MNLB. This provides a basis for the early prevention and control of MNLB and offers a valuable reference for early monitoring crop diseases with similar bottom-up progression.
Harnessing Genetic Tools for Sustainable Bioenergy: A Review of Sugarcane Biotechnology in Biofuel Production
Authors: Ahmad Kashif , Ming Ray
Published: August 2024

Sugarcane (Saccharum spp.) is a prominent renewable biomass source valued for its potential in sustainable and efficient second-generation biofuel production. This review aims to assess the genetic enhancement potential of sugarcane, emphasizing the use of advanced genetic engineering tools, such as CRISPR-Cas9, to improve traits crucial for biomass yield and biofuel production. The methodology of this review involved a thorough analysis of the recent literature, focusing on the advancements in genetic engineering and biotechnological applications pertinent to sugarcane. The findings reveal that CRISPR-Cas9 technology is particularly effective in enhancing the genetic traits of sugarcane, which are essential for biofuel production. Implementing these genomic tools has shown a significant rise in biomass output and, ultimately, the effectiveness of bioethanol manufacturing, establishing sugarcane as a feasible and reliable source of biofuel implications of these advancements extend. These advancements have a profound impact not only on agricultural productivity but also on enhancing the efficiency and scalability of the bioethanol industry. Developing superior sugarcane varieties is expected to boost economic returns and advance environmental sustainability through carbon-neutral biofuel alternatives. This review underscores the transformative role of genetic engineering in revolutionizing sugarcane as a bioenergy crop. The evolution of genetic engineering tools and methodologies is crucial for tapping into the full potential of sugarcane, and thereby supporting global efforts towards sustainable energy solutions. Future research should focus on refining these biotechnological tools to meet increasing energy demands sustainably, ensure food security, and mitigate negative environmental impacts.
Balanced Nitrogen Reduction for Improved Grain Yield and Eating Quality in Mechanically Transplanted Hybrid Indica Rice
Authors: Jiang Ming-Jin , Xu Wen-Bo , Li Li-Jiang , Zhang Jia-Feng , Wang Rong-Ji , Ji Guang-Mei , Luo Dan-Qiu , Jiang Xue-Hai , Tian Jin-Yu , Li Min
Published: August 2024

Excessive nitrogen application may adversely impact grain yield and quality of rice. This study aimed to evaluate the impact of several nitrogen-reduction strategies on the grain yield and quality of mechanically transplanted hybrid indica rice. Field experiments were performed in 2020 and 2021 using Yixiangyou2115 and Fyou498. The research investigated variations in grain yield and quality of rice under different nitrogen-reduction strategies, including NR1, balanced N reduction; NR2, N reduction in basal fertilizer; NR3, N reduction in tillering fertilizer; and NR4, N reduction in earing fertilizer, compared to the conventional nitrogen application for high-yield cultivation (CK). Compared to CK, the grain yield of rice decreased by 1.63% to 19.71% under nitrogen-reduction strategies. Relative to NR3 and NR4, NR1 and NR2 exhibited an increase in grain yield ranging from 1.81% to 22.51%, attributed to increases in panicle number (0.61% to 13.19%) and spikelet number per panicle (1.60% to 12.28%). Meanwhile, NR1 and NR2 also had relatively high LAI and dry matter accumulation in rice plants at maturity. Compared to CK, NR1 and NR2 improved the processing quality of rice grain, while NR3 and NR4 resulted in reduced processing quality. The chalkiness rate and chalkiness degree of rice under the NR1, NR3, and NR4 treatments were reduced by 2.97% to 23.73% and 3.35% to 52.49%, respectively, in comparison to CK. Additionally, the NR1 and NR4 treatments were linked to an increase in taste value by 1.44% to 3.66% and gel consistency by 13.87% to 46.01% relative to CK. These findings suggest that balanced nitrogen reduction can maintain a high yield while improving the appearance and eating quality of mechanically transplanted hybrid indica rice. This study offers a theoretical basis for rational nitrogen reduction and high-quality cultivation in rice.
Enhancing Disparity in Water Distribution within Irrigation Systems Aimed at Improving the Conflict Domain under Alternative Perspectives: A Reliable Multi-Objective Framework
Authors: Mahdi Moudi
Published: August 2024

In general, decision makers in irrigation systems prioritize the cultivation of diverse crops to ensure sufficient food supply and maximize economic profit, while overlooking ecological resilience. This study proposes a novel reliable multi-objective framework designed to minimize disparities in water distribution between multi-crops, thereby addressing conflicts related to irrigation timing and distribution space. To assess the feasibility of the proposed model, a reliability evaluation technique is employed to examine the conflict ratio of the water distribution policy corresponding to constraints concerning the available water and the water allocated to various crops (C-value). Next, to evaluate the reliable optimal multi-objective model, we examined the disparity of water distribution among four crops—fodder, watermelon, wheat, and grape—cultivated in three sub-areas of the Zayandehroud watershed, a watershed experiencing water shortage in the center of the Iranian plateau. Subsequently, given the overlooking of water conservation policies, this study investigates the impact of alternative perspectives on the disparity of water distribution and the conflict domain. The final results indicate that grapes exhibit lower sensitivity to water consumption, whereas watermelon is the most sensitive. In terms of the conflict domain, the city of Lenjanat recorded the least sensitivity.
Dynamic Evaluation and Risk Projection of Heat Exposure Based on Disaster Events for Single-Season Rice along the Middle and Lower Reaches of the Yangtze River, China
Authors: Jiang Mengyuan , Huo Zhiguo , Zhang Lei , Zhang Fengyin , Li Meixuan , Mi Qianchuan , Kong Rui
Published: August 2024

Along with climate warming, extreme heat events have become more frequent, severe, and seriously threaten rice production. Precisely evaluating rice heat levels based on heat duration and a cumulative intensity index dominated by temperature and humidity is of great merit to effectively assess regional heat risk and minimize the deleterious impact of rice heat along the middle and lower reaches of the Yangtze River (MLRYR). This study quantified the response mechanism of daytime heat accumulation, night-time temperature, and relative humidity to disaster-causing intensity in three categories of single-season rice heat (dry, medium, and wet conditions) using Fisher discriminant analysis to obtain the Heat Comprehensive Intensity Index daily (HCIId). It is indicated that relative humidity exhibited a negative contribution under dry heat, i.e., heat disaster-causing intensity increased with decreasing relative humidity, with the opposite being true for medium and wet heat. The Kappa coefficient, combined with heat duration and cumulative HCIId, was implemented to determine classification thresholds for different disaster levels (mild, moderate, and severe) to construct heat evaluation levels. Afterwards, spatiotemporal changes in heat risk for single-season rice through the periods of 1986–2005, 2046–2065 and 2080–2099 under SSP2-4.5 and SSP5-8.5 were evaluated using climate scenario datasets and heat evaluation levels carefully constructed. Regional risk projection explicitly revealed that future risk would reach its maximum at booting and flowering, followed by the tillering stage, and its minimum at filling. The future heat risk for single-season rice significantly increased under SSP5-8.5 than SSP2-4.5 in MLRYR. The higher risk would be highlighted in eastern Hubei, eastern Hunan, most of Jiangxi, and northern Anhui. As time goes on, the heat risk for single-season rice in eastern Jiangsu and southern Zhejiang will progressively shift from low to mid-high by the end of the twenty-first century. Understanding the potential risk of heat exposure at different growth stages can help decision-makers guide the implementation of targeted measures to address climate change. The proposed methodology also provides the possibility of assessing other crops exposure to heat stress or other extreme events.
Selection and Characterization of Somaclonal Variants of Prata Banana (AAB) Resistant to Fusarium Wilt
Authors: Ferreira Mileide dos Santos , Rebouças Tamyres Amorim , Rocha Anelita de Jesus , Oliveira Wanderley Diaciso dos Santos , Santos Ana Carolina Lima Santos dos , Jesus João Pedro Falcón Lago de , Ramos Andresa Priscila de Souza , Ferreira Claudia Fortes , Santos-Serejo Janay Almeida dos , Haddad Fernando , Amorim Edson Perito
Published: August 2024

Fusarium wilt, caused by the fungus Fusarium oxysporum f. sp. cubense (Foc), is one of the most devastating diseases affecting banana cultivation worldwide. Although Foc tropical race 4 (TR4) has not yet been identified in Brazilian production areas, the damage caused by races 1 and subtropical 4 is the main cause of production losses, especially affecting cultivars of the Prata subgroup. Thus, the induction of somaclonal variation is a promising strategy in biotechnology to generate genetic variability and develop resistant varieties. This study aimed to induce somaclonal variation in the Prata Catarina cultivar (AAB genome) using successive subcultures in Murashige and Skoog (MS) medium enriched with the plant regulator Thiadizuron (TDZ) at two concentrations: 1 and 2 mg/L. After evaluating the symptoms, we selected 13 resistant somaclones that were not infected by the fungus. Histochemical and histological analyses of the somaclones indicated possible defense mechanisms that prevented colonization and/or infection by Foc, such as intense production of phenolic compounds and the presence of cellulose and callose in the roots. Some somaclones showed no pathogen structures in the xylem-conducting vessels, indicating possible pre-penetration resistance. Furthermore, molecular studies indicated that the genetic alterations in the somaclones may have induced resistance to Foc without compromising the agronomic characteristics of the commercial genotype.