bluuebunny/crossref_metadata_2025 huggingface dataset:
MANAGEMENT OF BENIGN FIBROUS HISTIOCYTOMA AT SULTAN FATAH DEMAK HOSPITAL
Authors: Amiza Zam Syarifah Nova , Agustin Aisyah Nafa , Faadhila Annisa Husna , Annsya Resty , Fahrie Thania Olivia , Lathifa Ovie Luksita
Published: February 2025

Benign Fibrous Histiocytoma (BFH) is a benign soft tissue tumor consisting of fibroblastic and histiocytic cells. The most often affected locations by BFH lesions are the buccal mucosa, mandibular bones, gingiva, lower and upper lips, soft palate, and floor of the mouth. The etiology of BFH is unknown, but the etiology is thought to be reactive changes from previous infections such as insect bites or thorn pricks. Signs and symptoms of BFH include round-shaped swelling, appearing reddish at first, and turning brown. Case: A 40 year old male patient came to the Sultan Fatah Regional Hospital Demak with complaints of swelling of the left cheek below the eye, dizziness and fever for the last 7 days. Patients eat and drink with bread mixed in water or tea. The patient came in a compos mentis state, but the patient was less cooperative. Case management: The patient underwent incision and drainage. Tissue was taken for biopsy examination measuring 1 x 0.4 x 0.3 cm. The patient follow-up was carried out 7 days after the procedure. Results: Follow-up at 7 days after the procedure showed the patient's mouth opening was 1 cm. Conclusion: In this case, from subjective, objective, and supporting examinations, cause of infection has not been found. The treatment carried out is incision and drainage of the infection.
THE CORRELATION BETWEEN DENTAL MALOCCLUSION TO MIDLINE SHIFT AND BODY POSTURE OF JUNIOR HIGH SCHOOL STUDENTS
Authors: Parmasari Wahyuni Dyah
Published: February 2025

Background: The number of teenagers standing up straight according to normal posture is minimal. This results in it becoming a habit, so the body posture is not ideal in adolescence when the growth pattern is still ongoing. Early detection and intervention can help mitigate the impact of these issues on the student’s overall health, function, and quality of life. Methods: The design of this research is a cross-sectional and analytic observation. 70-person respondents were 1st-grade students of Junior High School 56 Surabaya. Outcome: In this study, the p-value obtained, was 0.06, a significant difference between the incidence of malocclusion in midline shift and body posture. Conclusion: There is a correlation between dental malocclusion to midline shift and body posture.
CURCUMA DOMESTICA AND MORINGA OLEIFERA EXTRACT GEL AS AN ALTERNATIVE FOR GINGIVAL BRIGHTENING: A PILOT STUDY
Authors: Pratiwi Devy Anugraeni , Bilqis Tsuraya , Fitriyani Rahma Dwi , Dewi Elya Mardhania Tiara , Rismawati Nadya , Sukmawati Ayuda Nur
Published: February 2025

Background: Gingival hyperpigmentation can occur in active smokers with high frequency. The current treatment is surgical. Therefore, researchers found a new breakthrough by creating a minimally extensive treatment, namely gel preparations. Combination of turmeric (Curcuma domestica) and moringa leaf (Moringa oleifera) extract that has the potential as a tyrosinase enzyme inhibitor. The extract will be made in a gel preparation. This study aims to determine the most optimal concentration of the gel. Method: This study used an experimental method. The gel preparation was made with various concentrations of turmeric extract and moringa leaf extract, namely F1 0.1%: 2%, F2 0.5%: 4% and F3 0.9%: 6%. Followed by testing the physical and chemical properties. Chemical properties in the form of pH, physical properties in the form of organoleptic, homogeneity, adhesiveness and spreadability by measuring the diameter of TB (No Load), B50 (Load 50 g), B100 (Load 100 g) and B150 (Load 150 g). Results: The results showed that F1, F2 and F3 were homogeneous with dark brown color, distinctive smell of moringa leaves and increasingly dilute form with each additional concentration with pH (F1) 7.99, (F2) 7.71 and (F3) 7.58. The spreadability of gel preparation F1 (TB) 2.7, (B50) 2.8, (B100) 2.9, (B150) 3.1; F2 (TB) 2.8, (B50) 3.1, (B100) 3.3, (B150) 3.5 and F3 (TB) 4.2, (B50) 4.6, (B100) 4.7, (B150) 5.1 based on these observations it is known that F3 meets the criteria for spreadability at a load of 150 gr. Conclusion: Based on this study, it can be concluded that F3 gel, a combination of turmeric extract and moringa leaf extract, has the most optimal formula because it almost meets all the requirements for gel preparations.
THE POWER OF RED SHOOT LEAF EXTRACT: HOW SOLVENT VARIATIONS AFFECT BONE HEALING AFTER TOOTH EXTRACTION IN RATS
Authors: Rachmawati, Sp.RKG Ika
Published: February 2025

Background: A popular medicinal plant in Indonesia, red shoot leaves (Syzygium myrtifolium Walp) have been extensively explored for their biological activity and potential to promote hard tissue healing in tooth sockets after extraction. However, few studies have examined this potential. Analyzing the impact of red leaf extract with different solvents on alveolar bone repair in the post-extraction socket in Wistar rats was the aim of this investigation.Method: This study aimed to determine differences in the healing process of bone after tooth extraction. Conducted on 15 male Wistar rats (12 weeks old, weighing 150 – 200 grams). The experiment includes three groups: Group A (5 animals received a gel base as a negative control group), Group B: (5 animals received 2% n-hexane gel treatment of red shoot leaves) and Group C (5 animals received 2% extract ethanol gel of red shoot leaves, based on designated observation days 30. The assessment involves bone remodeling area o from radiograph.Outcome: The average alveolar bone density varies greatly, as indicated by the study's p value of 0.000 (p < 0.005). The group that had 2% n-hexane gel treatment for red shoot leaves had the highest average alveolar bone density. According to the results of the phytochemical screening test, the n-hexane extract included triterpenoid and steroids, but the ethanol extract contained flavonoids, tannins, and alkaloids. The findings of this study demonstrate that the use of solvents with varying polarity can have an impact on bone remodeling.Conclusion: The alveolar bone mineral density of Wistar rats following tooth extraction was increased by 2% n-hexane gel treatment of red shoot leaves.
CLIMATE CHANGE AND INTERNATIONAL LAW: REVIEWING COMMITMENT FROM ASEAN AND EU
Authors: Sabatira Febryani , Knudsen Gustav , Saputra M. Febriyan
Published: February 2025

Climate change is a major issue occurring in our time. Global in scope and unprecedented in size, the repercussions of climate change include everything from changing weather patterns that endanger agricultural production to increasing sea levels that raise the possibility of catastrophic flooding. Considering the broad impact of climate change, all parties must take any measure necessary to address this issue, including primary regional organizations, namely the Association of Southeast Asia Nations (ASEAN) and the European Union (EU). This study examines the approach of ASEAN and the European Union regarding climate change that dramatically impacts the country's stability. Research shows that ASEAN-EU cooperation on climate change consists of 3 (three) main collaborations, namely Green Growth and the Environment, ASEAN-EU Statement on the Paris Agreement Reaffirming Commitment to Cooperation to Address the Shared Challenges of Climate Change, and The Second EU-ASEAN High-Level Dialogue on Environment and Climate Change. These forms of cooperation emphasize the commitment of the European Union as an advanced regional organization to support ASEAN in dealing with the impacts of climate change and implementing policies to reduce the use of carbon gas. In addition, the comparison of ASEAN and European Union policies on climate change ASEAN and the European Union is based on indicators according to Article 4 of the UNFCCC, which consists of progress, reduction of carbon gas emissions and greenhouse effects, adaptation and mitigation, and implementation of national policies. In addition, it can be seen that ASEAN policies are more in the form of a framework in conferences that reduce various regulatory instruments with each focus. At the same time, the European Union uses an approach in the form of an action plan that will be integrated into one law on climate change, namely the European Climate Law.
CRIMINOLOGICAL STUDY OF CORRUPTION IN ABUSE OF POSITION AUTHORITY
Authors: Linda Rosa , Prawira A. Yudha
Published: February 2025

In carrying out their duties and functions legally, officials have been regulated by law, but in exercising authority in office, they are also limited by law. Forms of abuse of power by public officials who commit corruption in a position and use it for personal and group interests to enrich themselves and certain groups and harm many people or the general public, namely in cases of corruption. Abuse of authority in office, namely in criminal acts of corruption by one of the university rectors in Lampung, followed by criminal acts of corruption in the Bengkalis Island Outer Ring Road improvement project and the Deputy Attorney General of the Manado State Attorney General’s Office. So, this needs to be studied in depth through criminological studies to determine the factors that cause someone to commit a crime. This study uses empirical normative research methods and statutory, conceptual, and case study approaches. The results of this study indicate that several factors influence an official who commits a criminal act of corruption. These internal factors include personality traits such as human greed, poor morals, and dishonesty. Next are external factors, including opportunity and economic factors (consumptive lifestyle). Efforts to deal with the criminal act of corruption and abuse of authority in the office can be carried out through preventive efforts, namely by building morale, honest attitude, and a clean work ethic. Then, through repressive efforts, severe penalties are imposed that create a deterrent effect and create fear for others to commit corruption.
DEEPFAKE IN ONLINE FRAUD CASES: THE HAZE OF ARTIFICIAL INTELLIGENCE’S ACCOUNTABILITY BASED ON THE INTERNATIONAL LAW
Authors: Davey Orima Melati , Sauerwein Levin
Published: February 2025

Artificial Intelligence (AI) is the science and engineering of intelligent machines, primarily through computer programs. AI consists of processes by human intelligence simulated through machine processes and is concerned with designing, developing, and implementing computer systems. One of them is Deepfake. Deepfake is a technology that uses data as an image/photo of a person’s face, which is part of personal data and potentially misused to commit crimes such as online loan fraud. The research discusses (1) the Benefits and Disadvantages of Artificial Intelligence in Human Lives, (2) the concept of accountability for deepfake artificial intelligence in online loan fraud according to international law and its application in Indonesia, and (3) the analysis of regulations and accountability of deepfake according to chaos theory. The research uses a legal-normative approach. Moreover, the research will examine legal principles, systematics, and comparative law in its application. The research illustrates that deepfake accountability as artificial intelligence in online loan fraud according to international law is described in the General Recommendation on the Ethics of Artificial Intelligence by The United Nations Educational, Scientific, and Cultural Organization (UNESCO). Meanwhile, the concept of accountability in Indonesia is seen in Human Rights and Data Privacy Violations. According to chaos theory, the analysis of Deepfake’s regulatory and accountability concept in international and national law leads to inconsistencies because it is only a recommendation, yet to be integrated, and still multidimensional.
IMPLEMENTATION OF GOOD GOVERNANCE IN JOKO WIDODO'S GOVERNMENT IN PROVIDING PEOPLE'S WELFARE
Authors: Rizqi Retanisa , Rahmaningsih Aziza Aziz
Published: February 2025

The implementation of good governance in the second period of Joko Widodo and Ma'ruf Amin aims to improve public welfare. This research analyzes several policies issued by Jokowi so that they can prosper the Indonesian people. This type of research is literature research. Literature study techniques carry out data collection. The results of this study show that the successful implementation of good governance in the Joko Widodo and Ma'ruf Amin administrations in improving public welfare and overcoming the COVID-19 pandemic was carried out through several programs. Some of these successes include controlling the COVID-19 pandemic, maintaining stable economic growth in the era of the COVID-19 pandemic, equitable development throughout Indonesia, showing Indonesia's existence in the international world, and starting the construction of a new national capital. These programs are a paradigm of human development, and the Indonesia-centric program not only makes development in Indonesia for the sake of growth in infrastructure but also encourages changes in the economy, encouraging the country to rise and form. Many governments are democratic, clean, and participatory both domestically and abroad. Through these programs, Jokowi places human welfare as the backbone so as to be able to give meaning to economic sectors that can alleviate poverty, expand opportunities for economic activity, reduce neglect of public services, reduce inequalities and disparities, strengthen social restoration and mental revolution, and eliminate repressive tyranny.
LAW ENFORCEMENT AGAINST PERPETRATORS OF CRIMES AGAINST STREET CHILDREN COMMITTED BY THEIR BIOLOGICAL PARENTS
Authors: Fajri Erfan , Suatmiati Sri , Hayatuddin Khalisah
Published: February 2025

Based on the cases in Palembang City, it can be said that law enforcement against perpetrators of crimes against street children committed by biological parents. The formulation of the problem in this study is 1) How is law enforcement against perpetrators of crimes against street children committed by biological parents in the Palembang City Police and 2) What are the factors that influence law enforcement against perpetrators of crimes against street children committed by biological parents in the Palembang City Police? The research method used is a type of empirical juridical research. The sources of data used in this study were primary and secondary data. Based on the results of the study show that law enforcement against the offenders of crimes against street children committed by biological parents in the Palembang City Police Resort, namely by penal measures through imprisonment as in Article 76I Jo Article 88 and Article 76C Jo Article 80 paragraph (1) of Law No. 35 of 2014 concerning amendments to Law no. 23 of 2002, concerning child protection or Article 44 Paragraph (1), Paragraph (4) of the Law of the Republic of Indonesia No. 23 of 2004. Factors that influence law enforcement against perpetrators of crimes against street children committed by biological parents, namely first, the factor of law enforcement officers. Lack of Investigators' Knowledge about Child Protection Law, Second, Community Factors. In cases of crime on the street, children tend to be closed, so it is difficult to socialize with the surrounding environment. Third, cultural factors that do not want to interfere in other people's personal affairs or other people's families or neighbors become a separate problem.
Fournier gangrene in a puerperal woman: An unusual presentation
Authors: Hancerliogullari Necati , Koç Esin Merve , Yaman Selen , Çolakoğlu Yeliz , Demir Berkcan , Şimşek Ahmet
Published: February 2025

Fournier’s gangrene (FG) is a localized form of necrotizing fasciitis that originates in the perineum and external genitalia. Its incidence is low, at 1.6 per 100,000, contributing to less than 0.02% of hospitalizations, and it is particularly rare in women. This report focuses on a case of FG in a 34-year-old woman who had recently undergone a cesarean delivery. The patient, a second-time mother with one previous birth, arrived at our hospital complaining of hip pain during her full-term pregnancy. Post-delivery, she was diagnosed with FG. Her most likely risk factor was a prior anal fissure and home-applied herbal therapy to the affected area. It is important to keep in mind that FG should be considered if an abscess develops in the urogenital region. FG is a potentially fatal infection that necessitates immediate diagnosis and treatment. Its effective management typically includes frequent and thorough debridement, broad-spectrum antibiotics, and diligent wound care.
Evolving Communicative Forms of the English Language in the Era of Globalization
Authors: Tiwari Monika , Saxena Rashmi
Published: February 2025

The rapid advancement of globalization and digital technology has significantly transformed the communicative forms of the English language. Traditional oral and written communication methods have evolved with the integration of mobile communication, social media, and digital platforms, leading to a shift in how individuals interact across urban and rural settings. Telephonic and mobile communication have emerged as the most widely used oral forms due to their accessibility, while SMS, websites, WhatsApp, and Facebook dominate written communication. However, platforms like email and fax remain confined to educational and professional domains, whereas blogging and Twitter are primarily used by literate individuals. The rise of digital communication has blurred the boundaries between literate and illiterate users, as smartphone accessibility has enabled broader engagement with online platforms. This study explores these changing communicative patterns, analyzing their impact on different demographics, including urban and rural users, as well as literate and illiterate populations. The findings highlight the dynamic nature of English language communication in the digital era and its implications for social interaction, professional engagement, and digital literacy.
Assessment of Physiotherapy Techniques in the Management of Sports Injuries
Authors: Almutaywia Alhanouf Abdullah , Alluhidan Maram Abdullah , Alanazi Nawal Awadh , Akkur Dalal Abdullah , Humaid Rasha Abdullah Bin
Published: February 2025

In the course of this qualitative study, the assessment of physiotherapy approaches for the management of sports injuries is investigated. More specifically, the research investigates how physiotherapists feel about various treatment modalities and how they view the effectiveness of these modalities. There were six physiotherapists who were questioned in order to have a better understanding of their experience and background in the field of injury treatment. For the purpose of data analysis, thematic analysis (TA) was used. Concerns over the use of advanced procedures, the inequality in treatment between professional and amateur athletes, the factors that influence injury recovery, the appraisal of injuries by physiotherapists, and the utilisation of specialist physiotherapy techniques were the key difficulties that emerged. After the athlete returned to play (RTP), all of the physiotherapists demonstrated a comprehensive understanding of the physical aspects of injury rehabilitation and how these aspects influence the performance of the player. However, the findings indicate that contemporary physiotherapy techniques are not usually used for the purpose of sports rehabilitation. A number of physiotherapists have expressed their belief that they do not possess sufficient time or resources, while others have said that they have a tendency to underestimate the efficacy of certain procedures. A total of five out of the six physiotherapists emphasised the need of using interdisciplinary approaches, such as collaborating with specialists, in order to enhance the outcomes of the healing process. According to the results, physiotherapists should continue their education and professional development in sophisticated techniques in order to improve their ability to handle injuries and to support more effective RTP strategies in the field of sports rehabilitation.
NEGOTIATING BETWEEN WORLDS: IDENTITY CRISIS AND CULTURAL DUALITY IN THE WORKS OF CONTEMPORARY INDIAN DIASPORIC WOMEN WRITERS
Authors: Nagpal Sabia , Wadhwa Poonam , Pant Girish
Published: February 2025

The experiences of Indian diasporic women writers reflect a profound negotiation between multiple cultural identities, leading to themes of identity crisis and cultural duality in their works. This paper explores how contemporary Indian diasporic women authors engage with questions of belonging, displacement, and self-definition. Through an analysis of selected works, the study highlights how these writers navigate their dual heritage, often balancing tradition with modernity, homeland with host nation, and personal agency with familial or societal expectations. The present paper is an honest attempt to attract the attention of the readers towards the Negotiating between Worlds: Identity Crisis and Cultural Duality in the Works of Contemporary Indian Diasporic Women Writers because their works address themes of alienation, hybridity, nostalgia, and redefinition of the self, often reflecting the tensions between cultural preservation and adaptation. The research scholar further writes that the literary narratives of authors such as Jhumpa Lahiri, Chitra Banerjee Divakaruni, Meena Alexander, Bharati Mukherjee, and Kiran Desai reveal the complex emotional and psychological struggles of women caught between two worlds. Additionally, the paper examines how gender plays a crucial role in shaping diasporic experiences, as women face unique challenges related to identity, tradition, and autonomy in a transnational context. By analyzing the literary techniques and thematic concerns of these authors, this paper contributes to the discourse on transnational feminism, cultural negotiations, and the evolving nature of identity in a globalized world.
TREATMENT OF WARFARE AND ENVIRONMENTAL CATASTROPHE IN THE 21ST CENTURY: INSIGHTS FROM TED HUGHES’S POETRY
Authors: Dhariwal Jaibir
Published: February 2025

War machinery plays havoc on both human and non-human world. The 20th century in human history has witnessed two World Wars and various minor wars. Loss of human lives, widespread displacements, trauma, climate change, pollution, and habitat destruction underscore the catastrophe looming over the planet in 21st century. Ted Hughes, a renowned British poet, has been placed among the greatest poets of the second half of the 20th century. The present research explores how Hughes’s poetry reflects the destructive impact of warfare on the environment. The research also delves into the profound connection between war and the environmental crisis in the present century. Environmental poetics is anti-War in principle and practice. Drawing upon Environmental poetics and ecocritical theory, this paper seeks to contextualize Ted Hughes’s work within the broader environmental discourse of the present era. Hughes’s poetic language, imagery and symbolism reveals the brutality of war and its horrendous consequences on the natural world. The brutality of wars reflects the instinct and bloody side of modern people and modern society. His poetic oeuvre also provides a lens through which to view and contemplate the destructive potential of human behaviour and its impact on the natural environment.
FROM AWARENESS TO ACTION: UNDERSTANDING SUSTAINABLE FASHION PURCHASES IN INDIA’S YOUTH
Authors: Singh Meenakshi , Somani Rashmi Sunil
Published: February 2025

Sustainable fashion apparel offers significant potential to reduce clothing waste, which is directly linked to societal health. This study explores consumer purchase behavior toward sustainable fashion apparel made from recycled materials. Supporting clothing recycling programs is crucial, and the success of these initiatives depends on consumer demand for recycled apparel. By examining consumer behavior and intentions toward sustainable fashion, this research provides a foundation for establishing effective regulations for clothing disposal and the purchase of recycled garments. Data were collected through a questionnaire distributed in the Punjab region of India, with 151 responses obtained. The findings reveal that several key factors influence the purchase intention of sustainable fashion apparel. Additionally, a positive correlation was found between sustainable clothing disposal behavior and the intention to purchase such apparel.
Testosterone deficiency and lower urinary tract symptoms in men.
Authors:   the Hormone Life Clinic, Grekov E.A. ,   Moscow, Russia, Kazachenko A.V. ,   N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology - Branch ofthe National Medical Research Centre of Radiology ofthe Ministry of Health of Russian Federation;Professor ofthe Department of Urology and Operative Nephrology with a course of oncourology of RUDN university; Moscow, Russia, Kalinchenko S.Yu. ,   the Department of Endocrinology with the course of Holis- tic Medicine of the Faculty of Continuing Medical Education of the Medical Institute of RUDN, Doctor of Medical Sciences, Professor; Moscow, Russia
Published: February 2025

Introduction. All epidemiological studies show that with aging in men, testosterone secretion gradually decreases, while the incidence of LUTS (Lower Urinary Tract Syndrom) increases with age, which also confirms the important role of age-related testosterone deficiency in the pathogenesis of LUTS in men. However, there are clearly not enough works in the modern scientific literature on the relationship between testosterone deficiency and LUTS in men, which was the reason for conducting this study. The purpose of the study is to study the frequency of testosterone deficiency (hypogonadism) in men with LUTS and to identify possible relationships between them.

The aim. Study the frequency of testosterone deficiency (hypogonadism) in men with various etiologies of LUTS and to identify possible relationships between them.

Materials and methods. The study included 120 men with lower LUTS aged 40-70 years (mean age 56,3±3,2 years, the main group) and 30 healthy men of the same age (mean age 54,4±4,9 years) who made up the control group. To clarify the nature of LUTS, a valid international questionnaire IPSS-QL was used, and a valid international questionnaire AMS was used to identify clinical symptoms of testosterone deficiency (hypogonadism). All the examined patients underwent finger rectal examination and prostate TRUSI and blood levels of total testosterone, sex hormone binding globulin (SHBG) and total PSA were determined. The level of free testosterone was calculated using the Vermeullen nomogram. The research results obtained during the survey were processed on an IBM-PC using EXCELL, XP SP2 systems based on the standard program Statistica for Window v. 6.0.

Results. Clinical and laboratory signs of testosterone deficiency (hypogonadism) were found in 57,5% of patients with LUTS. Lower levels of free testosterone were associated with more pronounced LUTS/nocturia and a higher incidence of congestive and inflammatory disorders in the prostate gland detected by finger rectal examination.

Conclusion. LUTS/nocturia can be considered as a potential symptom of testosterone deficiency (hypogonadism) in men, so when examining men with LUTS, it is necessary to conduct a simultaneous questionnaire on the IPSS-QL and AMS scales and subsequent hormonal screening.
Purple urine bag syndrome.
Authors:   the Department of Urology of the Federal State Budgetary Educational Institution of Higher Education «Saint Petersburg State Pediatric Medical University» of the Ministry of Health of the Russian Federation, Medical Director of the network of medical clinics «High Status», Zamyatnin S.A. ,   Saint Petersburg, Russia, Gonchar I.S. ,   Medical Affairs at the «High Status» network of medical clinics; Saint Petersburg, Russia
Published: February 2025

Introduction. Violet or purple urine bag syndrome is a rare manifestation of chronic urinary tract infection in patients with permanent urinary drainage. Mainly, such unusual urine coloration develops in women. Risk factors also include constipation, chronic kidney disease, increased consumption of products containing tryptophan, which is explained by the pathogenesis of this phenomenon.

Сlinical case. This article presents a case of purple urine coloration in a 75-year-old patient with urothelial bladder cancer. Recurrence of cancer and, as a consequence, multiple transurethral resections with subsequent courses of intravesical BCG and chemotherapy led to the development of microcystis, obliteration of the left ureteral orifice and hydroureteronephrosis. A nephrostomy drainage was installed on the left, through which, for the last two years, constant purple coloration of urine has been noted. During natural urination, the usual straw-yellow color of urine remains. Catheter-associated infection is represented by bacteria of the genus Morganella morganii.

Conclusions. A change in the color of urine to a purple hue indicates the need for urinary tract sanitation, as well as an analysis of the functional state of the kidneys and intestines.
Stereotactic radiation therapy for prostate cancer: state of the art radical treatment.
Authors:   N.N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation, St. Petersburg, Russia, Novikov R.V. ,   Professor of the Department of Urology, S.M. Kirov Military Medical Academy, Ministry of Defense of the Russian Federation, St. Petersburg, Russia, Ponomareva O.I. ,   N.N. Petrov National Medical Center of Oncology of the Ministry of Health of the Russian Federation; St. Petersburg, Russia, Bykova E.S. ,   N.N. Petrov National Medical Research Center of Oncology; St. Petersburg, Russia, Ilyin N.D. ,   N.N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation; St. Petersburg, Russia, Arsenyev A.I. ,   N.N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation, professor, department of oncology, I.I. Mechnikov North-Western State Medical University; St. Petersburg, Russia, Protoshchak V.V. ,   the department of urology, S.M. Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation; St. Petersburg, Russia, Karandashov V.K. ,   the department of oncourology of the urology clinic of the Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation; St. Petersburg, Russia, Lyasovich G.A. ,   the department of oncourology of the urology clinic of the Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation; St. Petersburg, Russia, Novikov S.N. ,   N.N. Petrov national medical center of oncology of the Ministry of Health of the Russian Federation; St. Petersburg, Russia
Published: February 2025

Over the past few years, radiation methods of treating prostate cancer have taken the first place in the level of recommendation in foreign oncourological practice. Stereotactic radiation therapy (STRT) is one of the most promising and high-tech methods of remote irradiation of prostate cancer. The STRT protocol was developed and introduced into clinical practice in the radiotherapy department of the N.N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation. The protocol developed and introduced into clinical practice methods aimed at achieving a high level of control over the tumor process and low rates of radiation-induced complications. Short treatment periods, high efficiency and low level of post-radiation complications provide grounds to consider this method as the optimal method of radical treatment of prostate cancer in low and in- termediate risk groups of relapse. 432 patients were treated with SRT in monotherapy (without combination with other methods of radiation treatment).
Treatment of prostate cancer by high-intensity ultrasound ablation and radical prostatectomy: a comparative analysis of long-term oncological results.
Authors:   the Department of Postgraduate Education of Samara Medical University «REAVIZ», Head of the Department of Interventional methods of diagnosis and treatment of GBUZ «SOKOD», Solovov V.A. ,   Samara, Russia, Tyurin A.A. ,   Medical University «REAVIZ», surgeon Clinical Hospital IDK, oncology department of surgical treatment methods; Samara, Russia
Published: February 2025

Introduction. To compare oncological efficacy of long-term follow-up of high-intensity focused ultrasound ablation (HIFU) and radical prostatectomy (RP) in the treatment of patients with prostate cancer.

Materials and methods. A comparative retrospective analysis included the results of treatment of 150 patients who underwent RP with 194 patients who received HIFU therapy in the period from 2008 to 2010 in the Samara Regional Clinical Oncology Center. To compare the oncological efficacy of both treatments, overall survival, cancer-specific survival, and recurrence-free survival were assessed. Biochemical recurrence was diagnosed based on ASTRO/Phoenix criteria. Statistical analysis used a one-dimensional logarithmic rank test, the Kaplan-Meier method.

Results. The mean follow-up time in the RP and HIFU groups were 14,5 and 15,2 years, respectively. The 15-year overall, cancer-specific, and disease-free survival rates were 28,3%, 77,7%, 53,7% in the RP group and 48,0%, 79,4%, 69,8% in the HIFU group, respectively. Prognostic factors were PSA level before treatment, Gleason score. The results of HIFU therapy compared with RP demonstrated comparable cancer-specific and disease-free survival rates.

Conclusion. HIFU therapy may be an alternative treatment for patients with PCa low and intermediate risk progression according to D'Amico. Patients with high-risk progression should be informed about possible repeat HIFU sessions and/or adjuvant treatment. In long-term follow-up, HIFU therapy compared to RP has shown a higher overall survival with comparable values of cancer-specific and relapse-free survival in the treatment of patients with prostate cancer.
Modern methods of diagnosis and treatment of erectile dysfunction.
Authors:   the Center of Urology and Andrology FMBC them. A.I. Burnazyan FMBA of Russia, Kyzlasov P.S. ,   Moscow, Russia, Burdin K.A. ,   State Budgetary Healthcare Institution of the Moscow Region «Domodedovo Central City Hospital», Domodedovo, Russia, Khvorov V.V. ,   the Center for Surgery and Urology, urologist; National Diagnostic Center, LLC; Shchyolkovo, Russia, Mitin A.A. ,   the Outpatient Urology and Andrology Department, urologist; National Diagnostic Center, LLC; Shchyolkovo, Russia, Belov V.O. ,   the Urology Department of the Center for Surgery and Urology; National Diagnostic Center, LLC; Shchyolkovo, Russia
Published: February 2025

Introduction. Erectile dysfunction (ED) is one of the most relevant topics of study. Over time, diagnostic and treatment algorithms have repeatedly changed. This literature review provides a modern classification of erectile dysfunction, a step-by-step approach to diagnostics, and modern methods of treating various forms of erectile dysfunction.

Objective. To study the etiological causes and modern treatment for erectile dysfunction.

Materials and methods. A search was conducted using the keywords «erectile dysfunction», «impotence», «phosphodiesterase type 5 inhibitors», «penile reinnervation», «corpora cavernosa revascularization» in the PubMed, Cyberlennika, and еLibrary databases. The inclusion criteria included publications in Russian and English. As a result, 53 publications were selected and included in this review.

Results. For a long time andrologists have been studying the topic of ED, now new research methods are emerging, X-ray endovascular technologies are actively developing. Possible prospects lie in the combination of various treatment methods to improve the outcome.

Conclusions. Erectile dysfunction is multifaceted and requires a multidisciplinary approach to improve the patient's quality of life.
Androgen receptors in the development and progression of benign prostatic hyperplasia.
Authors:   the Department of Public Health No. 1, Esin A.V. ,   Voronezh, Chief freelance specialist in urology in the Voronezh City District, Ministry of Health of the Voronezh Region, Russia,   Voronezh, Russia, Zolotukhin O.V. ,   the Department of Medical Education No. 1, Chief Freelance Specialist in Urology of the Ministry of Health of the Voronezh Region, Doctor of Medical Sciences, Associate Professor, Head of the Department of Urology of the N.N.Burdenko VSMU of the Ministry of Health of the Russian Federation; Voronezh, Russia, Madykin Yu.Yu. ,   the Department of Urology of the N.N.Burdenko State Medical University of the Ministry of Health of the Russian Federation, Chief freelance specialist in Reproductive Health of the Ministry of Health of the Voronezh Region; Voronezh, Russia, Avdeev A.I. ,   the Department of Urology of the N.N.Burdenko State Medical University of the Ministry of Health of the Russian Federation; Voronezh, Russia
Published: February 2025

Introduction. One of the most common urological diseases of aging men is benign prostatic hyperplasia (BPH). Androgens and androgen receptors (AR) are essential for the proper development and functioning of the prostate of an adult, and research is ongoing to understand the mechanisms involved in androgen availability, transport and activity of AR in the prostate.

The aim. To review current research on evidence of the involvement of androgen receptors in the development and progression of BPH.

Materials and methods. Using the databases eLibrary, PubMed, Cochrane Collaboration and Embase, the search and analysis of publications over the past 20 years have been carried out. The key words were: benign prostatic hyperplasia; BPH; prostate; androgens; androgen receptors. The inclusion criteria were: prospective (cohort) studies and randomized clinical trials. The total number of sources included in this review was 40.

Results. The review highlights the following sections: anatomy and function of pancreas, the role of androgens (A) and AR in the development and progression of BPH, unresolved issues of BPH pathogenesis, conclusions. An analysis of the work showed that changes in the expression/transmission of AR signals play an important role in the pathogenesis of BPH. However, there are still questions that need to be answered. Is BPH caused by the «awakening» of the pancreatic stroma with increased AR expression? Can BPH be initiated by a violation of AR signaling in the cells of the pancreatic lumen? On the one hand, many studies have proven a positive relationship between AR activity and the progression of BPH, however, there are works demonstrating alternative conclusions, consisting in the fact that suppression of AR activity, increased inflammation in the pancreas contribute to increased cell proliferation, and the progression of BPH.

Conclusion. The mechanisms of AR involvement in the development and progression of BPH have not yet been clarified. New research in this area is needed.
Pemberdayaan Teknologi Digital dalam Pemblajaran di SMP NW Mataram melalui Program Kampus Mengajar
Authors: Kasyif Muhammad Kasyiful Kurabi , Azmi Ema Suryani , Arini Sholeha Lidya
Published: February 2025

The Kampus Mengajar Program aims to improve the quality of education in schools through collaboration between students and teaching staff. This article discusses the implementation of digital technology in learning at NW Mataram junior high school, with the aim of improving students' literacy, numeracy and digital skills. Implementation methods include observation, teaching assistance, technology training, and learning assessment. The results show that the use of digital technology such as interactive PowerPoint, learning applications, and online-based assessments increases student motivation and understanding. However, obstacles such as limited internet access are still a challenge. Recommendations are given to strengthen training for teachers and students in optimal use of digital technology.
Diálogos interdisciplinares 16
Authors: Grijó Andréa Pinheiro Techio Pereira , Cruz Fernanda Monteiro da , Guimarães Sueli do Nascimento , Graça Beatriz Alves , Landa Giovanni Guimarães , Costa Dhiego Mattos , Cruz Fernanda Monteiro da , Carvalho Janaína Brandão , Araújo Márcia Moreira de , Peçanha Luana Moreira de Souza , Lago Vivian Miranda , Nicoli Luciana Barreto , Garcia Anilton Salles , Lima Marileis Baptista , Baiense Tatiana Leal , Pinheiro Suelen Silva , Nunes Marcus Antonius da Costa , Brandão Mary da Silva Costa , Silva Joccitiel Dias da , Agapito Rodrigo da Fonseca , Gonçalves Douglas Cerqueira , Rizzi Vanessa Santana Maciel , Guisso Luana Frigulha , Pimenta Yuri do Nascimento , Arantes Sara Dousseau
Published: February 2025

A publicação objetiva compartilhar as pesquisas, realizadas por alunos, com o acompanhamento de seus professores-orientadores, no Mestrado em Ciência, Tecnologia e Educação do Centro Universitário Vale do Cricaré (UNIVC), com o objetivo de desvelar a construção do saber, consolidado no âmbito acadêmico.
Produto educativo de aprendizagem - Urgência, Emergência e Técnicas de Enfermagem II
Authors: Oliveira Carolina Furtado de , Haubenthal Natalia Alini , Silveira Natália Lançanova da , Vasconcelos Janine , Gehlen Maria Helena , Brum Luciele , Silva Fabiana Porto da , Rodrigues Cristina dos Santos de Freitas
Published: February 2025

Bem-vindos ao Manual Didático de Urgência, Emergência e Técnicas de Enfermagem!
Esse material consiste em um produto educativo ilustrado desenvolvido na disciplina de Urgência, Emergência e Técnicas de Enfermagem II (UETE II), tendo por objetivo fornecer suporte de consulta, acompanhamento e estudo das aulas práticas aos alunos da graduação do curso de Medicina da Universidade Franciscana (UFN). Sendo este cuidadosamente elaborado para fornecer ao leitor uma base sólida de conhecimentos científicos e habilidades essenciais para atender as diferentes situações presentes na prática médica.
O manual foi preparado pelas monitoras da disciplina prática no ano de 2024, orientadas pelas professoras Janine Vasconcelos, Mestre em Saúde Materno Infantil pela UFN e Doutoranda pelo Programa de Pós-Graduação em Enfermagem (PPGENF) da Universidade Federal de Santa Maria (UFSM), Luciele Budel, Mestre em Saúde Materno Infantil e Maria Helena Gehlen, Mestre em Educação Brasileira pelo Programa de Pós-Graduação em Educação (PPGE) da UFSM e Doutora em Gerontologia Biomédica pela Escola de Medicina da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Fabiana Porto da Silva, Mestre em Saúde Materno Infantil e Cristina dos Santos de Freitas, Mestre em Saúde Materno Infantil, professoras da disciplina de UETE II.
Este produto educativo foi preparado com muito carinho e dedicação, ficamos honradas em disponibilizar aos acadêmicos e colegas um material completo, didático e científico que lhes auxilie nas horas de estudos e torne-os capacitados para atuar com excelência.
Todos os direitos são reservados as autoras, não sendo permitida a reprodução e divulgação deste material de forma livre, sem autorização das mesmas, pois o manual contém fotos provenientes de acervo particular.
Desejamos a todos uma jornada de aprendizado gratificante e enriquecedora!
Inviting Culture into Her Wellness: The Moderating Effects of African Centered Coping on Suicide Risk Factors Among Black Women
Authors: Oliphant Vanessa , Wingate LaRicka , Benson Olufunke
Published: February 2025

There is a need for greater emphasis to be placed on the lived experiences of Black women in psychological research, and more specifically, Black women’s experiences with suicide ideation. Despite having the lowest suicide rates, prior research indicates an increase in suicide ideation among Black women and girls. The current study aims to evaluate the moderating effects of Black women’s implementation of culturally specific ways of coping (i.e., Africultural coping skills) to pinpoint protective strategies against interpersonal suicide risk factors, thwarted belongingness, and perceived burdensomeness. 99 (M age = 23) cisgender African American/Black women were surveyed, and results indicated that spiritual centered coping both significantly and negatively moderated the relationship between perceived burdensomeness and suicide ideation (B = -0.00, t = -2.29, p = .02, 95% CI [-.0085, -.0006]). Additionally, ritual centered coping significantly and negatively moderated the relationship between perceived burdensomeness and suicide ideation (B = -.009, t = -2.05, p = .04, 95% CI [-.0179, -.0003]). Findings suggest that spiritual and ritual centered coping can be protective strategies for Black women by weakening the relationship between suicide ideation and the interpersonal suicide risk factor perceived burdensomeness.
Content and Language Teaching: An Evolving Pedagogy for Vietnamese English-Medium Lecturers
Authors: Vu Thi Thanh Nha
Published: February 2025

Content and language teaching has been widely applied in language education. The recent popularity of content and language-integrated learning (CLIL) and English-medium (EMI) courses has caused increasing research interest in exploring the relationships between language and content for an effective pedagogy. However, content and language-based teaching is elusive regarding contextual, disciplinary, and personal diversity, resulting in mixed classroom practices. Based on a questionnaire with 72 EMI lecturers, this paper explores the evolving nature of content and language teaching and how these EMI lecturers translated its teaching principles into practice. The findings revealed that most EMI lecturers perceived their dual role of supporting content and language development in EMI courses partly translated into classroom practices. Classroom activities primarily focused on lecturing, and language support strategies were integrated with content learning. The paper concludes with implications for teaching and further research.
Language Branding: A Methodological Approach to Measuring the Brand of the Basque Language
Authors: Garai-Artetxe Estitxu , Irati Agirreazkuenaga  , Irene García-Ureta  , Sergio Monge  , Angeriñe Elorriaga-Illera  , Ainara de Miguel  , Amaia Paniagua
Published: February 2025

This article introduces a pioneering concept in the field of language promotion: language branding. Branding mechanisms offer a novel framework for modernizing and enhancing linguistic planning efforts. Drawing on brand analysis theories from the commercial domain, this study develops a methodology to assess the brand image of languages. Addressing brand image is essential, as the construction of a language's brand can significantly influence speaker preferences. The research presents the first applied case by analyzing the brand image of the Basque language, a minority language supported by an organized revitalization movement with both institutional and grassroots backing. The study employs an innovative methodology rooted in branding literature, adapting it to the linguistic field through a combination of qualitative exploratory methods (focus groups) and quantitative brand measurement techniques (surveys). The Basque language brand is evaluated across several hierarchical dimensions: awareness, associations, attitudes, attachment, and activity. The results reveal that Basque enjoys a high level of emotional attachment among speakers. However, its brand associations remain heavily tied to a symbolic and mythical traditional imagery, which limits its perception as a practical tool for everyday communication.