bluuebunny/crossref_metadata_2025 huggingface dataset:
Controle interno na saúde suplementar por meio da ouvidoria: accountability horizontal
Authors: Fernandes André Dias , Pontes Cláudia Taís Fontenele
Published: January 2023

O objetivo deste estudo é apresentar reflexões teóricas sobre a atuação das ouvidorias dos planos de saúde como mecanismo institucional de accountability horizontal. Discorrer sobre como as ouvidorias podem funcionar como controle interno limitado, seja no setor público, por meio do exercício da participação social do cidadão, seja no setor privado pelas reclamações e sugestões de seus consumidores, dando destaque a atuação da ouvidoria como accountability horizontal na saúde suplementar. A metodologia de abordagem é empírico exploratório, com apresentação de dados realizado através de pesquisa bibliográfica e de pesquisa documental. Apresentam-se inicialmente os aspectos da accountability horizontal no Brasil, seguido do desempenho das ouvidorias como forma de controle interno e participação social, para ao final estabelecer a relação entre ouvidoria na saúde suplementar como mecanismo de accountability horizontal. Concluiu-se que as ouvidorias desempenham importante papel como canal de comunicação entre o cidadão / consumidor e a Administração Pública / setor privado, como forma de accountability horizontal para o controle e participação social, mas para tanto é importante que lhes seja garantido os atributos necessários como autonomia e independência, sob pena de ter seu significado esvaziado.
Oversharenting e o direito de ser esquecido: como conciliar a liberdade dos pais com a privacidade e a intimidade dos filhos
Authors: Albuquerque Paulo Germano Barrozo de , Carvalho Ana Paula Vieira
Published: January 2023

Nos últimos anos, a utilização de redes sociais aumentou consideravelmente, permitindo que as pessoas compartilhem informações de forma rápida. Verificou-se, com esse cenário, um aumento da autoexposição dos indivíduos. O fato gera maior preocupação quando envolve a superexposição da intimidade e da privacidade de crianças e de adolescentes. Mesmo sem a intenção de prejudicar os filhos, os pais podem expor crianças e adolescentes a diferentes riscos. Este estudo tem, como objetivo, avaliar o direito ao esquecimento, no contexto do oversharenting, como importante instrumento para a proteção da intimidade e da privacidade dos filhos. Utiliza-se o método dedutivo, com uma abordagem qualitativa, descritiva e teórica, realizada a partir de pesquisa bibliográfica em livros, artigos jurídicos e legislações brasileiras e estrangeiras, para se concluir que, apesar de o ordenamento jurídico brasileiro ainda não contemplar o direito ao esquecimento, sua implementação em casos de oversharenting é fundamental ao desenvolvimento da personalidade dos filhos.
Tratamento do superendividamento: considerando a parcela do financiamento habitacional como despesa do mínimo existencial
Authors: Comaru Jeremias Reis
Published: January 2023

A proteção ao direito do consumidor recebeu uma importante contribuição com a publicação da Lei do Superendividamento, Lei 14.181/2021 que determinou alterações no Código de Defesa do Consumidor, Lei 8.078/1990. Além de possibilitar a renegociação dos créditos junto aos credores, a alteração permite a reinserção do devedor no mercado de crédito, preservando o valor referente ao mínimo existencial, sem que, no entanto, tenha sido regulamentada uma metodologia de cálculo para mensurar tal valor. O trabalho busca responder ao seguinte questionamento: é possível inserir a parcela mensal do financiamento habitacional no cálculo do mínimo existencial do superendividado? Acredita-se que o direito à moradia como direito fundamental previsto constitucionalmente permita que a parcela do financiamento habitacional seja considerada no cálculo do mínimo existencial, dado a centralidade que o direito à moradia tem na realização de tantos direitos relacionados à dignidade da pessoa humana e à ampla proteção que a casa, em sentido amplo, recebe na legislação pátria. A natureza da presente pesquisa é qualitativa, teórica e jurisprudencial, com a utilização do método dedutivo.
A pesquisa na formação de Profissionais de Saúde
Authors: Duarte Ana Carolina , Ribeiro Breno Samuel , Jonas Bruna Simões , Paula Caio Cesar de , Paula Caio César de , Silveira Fernanda Bentivoglio , Ferreira Maria Eduarda Barcelos , Ferreira Mariana , Freitas Moara Moreira , Gracioli Sofia Muniz Alves , Trancho Helena Lamberti , Seixas Maria Clara Del Lama , Lima Rafael Pimenta De , Andrade Michele Santos do Nascimento- , Nascimento Maria Eduarda Vilaça , Dib Maria Clara Dourado , Alves Maria Cherubina de Lima , Giacomini Marcia , Redondo Letícia Alpino , Bomfim Irma Helena Ferreira Benate , Vicente Ingrid Rodrigues
Published: January 2023

Esse e-book foi produzido, a partir de estudos apresentados no XVI Congresso de
Iniciação Científica do Centro Universitário Municipal de Franca - Uni-FACEF, sendo
composto por pesquisas teóricas e empíricas, realizadas por estudantes de
graduação da área da Saúde. As temáticas abordadas são diversas, contribuindo
para uma formação humanizada dos profissionais, além de trazerem um olhar lúcido
sobre questões biopsicossociais relevantes na atualidade.
As pesquisas apresentadas revelam o quanto essa prática investigativa e reflexiva,
realizada por profissionais de saúde em formação, contribui para a construção de
uma postura crítica e humanizada diante de questões e temáticas importantes que
permeiam o cotidiano de nossa sociedade atual. Os pesquisadores graduandos,
autores dos trabalhos expostos, revelaram sua contribuição com a Ciência ao
produzirem conhecimento na sua área de atuação, além de se mostrarem sensíveis
e perspicazes quanto aos problemas de seu tempo, buscando soluções éticas e
transformadoras
Repercussões sociais em pesquisa
Authors: Nalin Ana Paula Rodrigues , Spinieli André Luiz Pereira , Nascimento Emily Alves do , Barbosa Guilherme Dalbon , Lima Jaqueline de Queiroz , Bensi Júlia Alves , Giacomini Marcia Aparecida , Prata Mariana Estanti , Barbosa Mirela Coelho de Senne , Santos Thalita Ferrari dos , Lourenço Sara Gabriela Domingos dos Reis , Oliveira Roberta de Souza , Trovão Ana Carolina Garcia Braz , Gracioli Sofia Muniz Alves , Borges Paulo César Corrêa , Santos Patrícia Reis Alves dos
Published: January 2023

É com alegria que recebi o convite para prefaciar um dos nove volumes de artigos
resultantes de pesquisas de Iniciação Científica apresentados durante o XVI Fórum
de Estudos Multidisciplinares e XVI Congresso de Iniciação Científica, promovidos
pelo Uni-FACEF, em maio de 2022, sobre a temática do “Social” que afeta cada e
todas as pessoas do universo.
O leitor encontrará aqui reflexões de jovens pesquisadores de três importantes
instituições de ensino superior de Franca-São Paulo: o Uni-FACEF; a Unifran e a
UNESP.
O Congresso revelou grande preocupação com a pessoa idosa – a proteção social
do idoso revelou “desproteção” e mostrou que o idoso negro, a mulher idosa foram
os grandes atingidos pela pandemia da Covid-19. Os jovens pesquisadores da
medicina fizeram propostas de Avaliação Geriátrica Ampla-AGA, para melhoria do
processo de cuidado da pessoa idosa. A beleza do Congresso está na multivisão e
há proposta de jovens pesquisadores para o preparo do idoso para essa fase da
vida mediante o planejamento financeiro. E, quanto à saúde mental e o conceito de
morte e de luto para essa fase da vida, um dos caminhos da pesquisa indicou a
análise e o conhecimento do contexto psicossociocultural vivido pela pessoa idosa.
Sobre a mulher, os artigos foram ricos em observá-la sobre o ponto de vista da
violência que sofre em virtude de relações de poder e a consequente necessidade
de políticas públicas protetoras, defendidas pelo Serviço Social. Sobre seus direitos,
os jovens pesquisadores do Direito trouxeram o instituto do “Habeas Corpus
124306”, que trata do espinhoso tema do aborto.
As crianças e os adolescentes aparecem nos trabalhos dos jovens pesquisadores
como questão social a ser enfrentada do ponto de vista da violência sexual que
sofrem e que foi agravada com a pandemia Covid-19, com políticas públicas
vigorosas. E, sobre os infratores menores as pesquisas revelam a necessidade de
aprimoramento do sistema de medidas protetivas à evitar reincidências.
O jovem pesquisador, ao apresentar o seu trabalho com pessoas com deficiência,
propõe medidas para além do paradigma social e que se inclua o modelo dos
direitos humanos.
A fome e a pobreza mobilizaram o pesquisador iniciante à reflexão do assunto à luz
do modo como se produz e reproduz capitais na sociedade.
Pesquisa em saúde
Authors: Lima Amanda Sarah , Garcia Ana Beatriz Bertoloni , Silva Ana Carolina da , Souza Ana Lívia de Almeida , Rezende Beatriz Cezarino , Murari Carla Porto Cunha , Sartori Carolina Ferreira , Barbosa Kelly Jacquelina , Noventa Maria Antonia , Sampaio Viviane Rodrigues Esperandim , Sarreta Fernanda de Oliveira , Caetano Gabriella Fernandes Oliveira , Gracioli Sofia Muniz Alves , Fracalozzi Jonas de Lara , Ferreira Valéria Beghelli , Valentim Maria Eduarda Silva , Simões Tiago Custodio , Freitas Thaís Fernanda Morais , Pedrucci Maria Giulia , Lima Pamela Borges , Carmo Nicole Germano de Lima do , Silva Nádia Maria Lemos da , Negrinho Nádia Bruna Silva , Oliveira Maria Rita Vieira de , Barbosa Luiza , Silva Lilian Puglas da , Anawate Laura Nassif , Silva Larissa dos Santos , Rodrigues José Guilherme Vitório
Published: January 2023

Este livro foi organizado como resultado das apresentações e
discussões de pesquisas durante a realização do XVI Fórum de Estudos
Multidisciplinares, XVI Congresso De Iniciação Científica, XI Encontro De Iniciação à
Docência, X Encontro de Iniciação Tecnológica e Inovação e III Encontro PETSaúde, I Encontro de Iniciação Cientifica Júnior ocorridos no mês de maio de 2022,
no Uni-FACEF Centro Universitário Municipal de Franca. O tema principal destes
estudos, neste e-book, é a área da saúde, perpassando por questões que abordam
as diversas situações de vulnerabilidade individual e coletiva que podem impactar
diretamente o processo saúde doença de toda sociedade, além de abordar estudos
sobre o processo de aprendizagem de estudantes da área da saúde, em especial os
cursos de enfermagem e medicina.
Diante disto, fica evidente a grandiosidade e a diversidade de assuntos
sobre a área da saúde publicados nesta obra. Espera-se que estes estudos sejam
disparadores de novas pesquisa, para fortalecerem o conhecimento cientifico, a
produção de saúde e da educação médica e de enfermagem.
Estereotipos de género e imagen corporal presentes en publicidad audiovisual
Authors: Villalobos Reyes Paloma , De Luzia Nanjareth Gianini Ivania Arriagada , Muñoz Tapia Alejandra Debora
Published: January 2023

El patriarcado, entre otras cosas, ha dictado también las normas de cómo percibimos y cómo debemos percibir los cuerpos de las otras personas y el propio, de ahí la importancia de analizar las formas de reproducción de estos estereotipos adquiridos cultural y socialmente, por ejemplo, a través de la publicidad. Este estudio realiza un análisis de contenido de ocho comerciales emitidos en la televisión chilena en los últimos treinta años que presentan estereotipos de género e imagen corporal femeninos, en donde se aplicó el debate teórico en torno a la belleza, los cuerpos hegemónicos, las redes sociales, los movimientos sociales y otros, a videos publicitarios que en su época levantaron muy pocas sospechas, a partir de lo cual se obtuvo, entre varias conclusiones, que incluso los comerciales más actuales y “feministas” no están libres de estereotipos dañinos.
Entre o mainstream e o underground
Authors: Rosa Tiago Barros
Published: January 2023

Trata-se de um estudo comparativo entre dois polos do rock brasileiro dos anos 1980 – o mainstream e o underground –, empreendido por meio do estudo da trajetória individual e coletiva dos roqueiros brasileiros do período, em diálogo com conceitos de Pierre Bourdieu, buscando identificar os capitais detidos pelos expoentes do rock que receberam a preferência da indústria fonográfica do período, em comparação com um segundo grupo, que ficou à margem da indústria da música. A pesquisa aponta que os distintos capitais (social, cultural e econômico) detidos pelo primeiro grupo foram condicionantes importantes para o recrutamento destes pela indústria da música, catapultando-os para o sucesso comercial e a consagração artística, em detrimento do segundo grupo, que não dispunha dos mesmos trunfos materiais e simbólicos.
Temperatura no ático de modelos reduzidos de aviários com diferentes tecnologias de isolamento térmico do telhado
Authors: Vieira Neto José Gabriel , Souza Carlos Henrique , Silva Rodrigo Pinheiro
Published: January 2023

Objetivou-se determinar e comparar a temperatura interna do ático de modelos reduzidos de aviários com diferentes tecnologias de isolamento térmico no telhado. Analisou-se nove modelos reduzidos, sendo que três deles apresentaram cobertura somente com telha metálica (telha zincada); três com associação desta telha zincada com manta térmica (conhecida como manta asfáltica); e outros três modelos com associação da telha metálica com placas de Poliestireno Extrudado (XPS). A análise de temperatura foi realizada através de sensores DS18B20 instalado no ático, 15 cm acima do forro de cada modelo reduzido e mais um sensor na parte externa para comparação da temperatura do ambiente interno com a variação externa. Concluiu-se que, quando se teve a maior temperatura externa absoluta, os modelos com aplicação da placa XPS tiveram a temperatura do ático menor, em média 3,4°C quando comparado apenas com a telha de zinco, apresentando-se como melhor tecnologia dentre as testadas, sendo tecnicamente uma opção viável para aplicação nas construções zootécnicas, tendo em vista sua maior capacidade de isolamento térmico. Já a manta asfáltica não apresentou eficiência no isolamento térmico, possuindo características térmicas próximo ao comportamento da telha metálica, principalmente em condições de temperaturas elevadas.
Comparação de métodos de estimação do tamanho ótimo de parcela em sorgo e crotalária spectabilis
Authors: Cargnelutti Filho ​Alberto , Silveira Daniela Lixinski , Bubans Valéria Escaio , Somavilla Felipe Manfio , Osmari Bruno Fillipin
Published: January 2023

O objetivo deste trabalho foi comparar dois métodos de estimação do tamanho ótimo de parcela para avaliar a massa de matéria fresca de sorgo (Sorghum bicolor (L.) Moench) e crotalária spectabilis (Crotalaria spectabilis Roth.). Foram conduzidos 15 ensaios de uniformidade com sorgo e crotalária spectabilis, em cultivo solteiro e em consórcio. Foi avaliada a massa de matéria fresca em 540 unidades experimentais básicas (UEB) de 1 m × 1 m (36 UEB por ensaio). Foi determinado o tamanho ótimo de parcela por meio dos métodos da curvatura máxima modificado e do modelo linear de resposta com platô. Maior tamanho ótimo de parcela e, consequentemente, maior precisão experimental é obtido pelo modelo linear de resposta com platô em comparação ao método da curvatura máxima modificado. O tamanho ótimo de parcela para avaliar a massa de matéria fresca de sorgo e crotalária spectabilis, em cultivo solteiro e em consórcio é 8,23 m2.
Biofertilizantes em pulverização foliar: efeito nas caraterísticas agronômicas e produtividade de soja
Authors: Cruvinel Alexandre Moreira , Santos Júlio Cesar Neves dos , Pereira Igor Souza , Gualberto Camila de Andrade Carvalho , Penha Henrique Gualberto Vilela
Published: January 2023

Para obtenção de maiores produtividades em lavouras de soja, o uso de novos produtos, a exemplo dos biofertilizantes, tem tido boa aceitação pelos produtores, seja para aplicação via solo ou foliar. Desse modo, o objetivo do presente estudo foi avaliar o efeito dos biofertilizantes comerciais VitaComplex® (a base de melaço de cana-de-açucar + aminoácidos) e AminoVita® (a base de ácido cítrico, sacarídeos e resíduos de abate de animais) em caracteres agronômicos e produtividade da soja. Os produtos foram aplicados via foliar em estádios vegetativos e reprodutivos. Foram avaliados a altura de plantas, diâmetro de caule, SPAD, carbono orgânico foliar (C.O) e produtividade. Diâmetro de caule altura, índice SPAD e C.O não apresentaram diferenças estatísticas significativas em função das doses testadas. Para produtividade, houveram ganhos de até 1,78 t ha-1, quando comparado ao tratamento controle. Tanto a aplicação individual ou em conjunto dos produtos testados ocasionaram aumentos na produtividade de soja.
“SALTO PSICOLÓGICO”: ANÁLISE DA EPIFANIA NOS CONTOS AMOR E CENA EM SUSTENIDO
Authors: Onofre Santos Ana Maria , Lins Precioso Adriana
Published: January 2023

Este artigo se propõe a fazer uma breve análise comparativa sobre os contos Amor, na obra Laços de família (2009), de Clarice Lispector e o conto Cena em Sustenido, na obra Buquê de Línguas (2008), de Tereza Albues, e tem como objetivo principal compreender as semelhanças e diferenças dos elementos narrativos apresentados nos contos, além de trazer uma reflexão acerca dos momentos epifânicos individual e coletivo nos textos, característica que aproxima as duas escritoras. O arcabouço teórico que fundamenta este texto está principalmente voltado para os estudos de Candido (2006) sobre textos literários, mas também para outros críticos e teóricos como Osman Lins (1976), Tania Franco Carvalhal (1986), Stuart Hall (2006), entre outros.
Results of the development of the technology of light-weight concrete based on diatomite rocks and instrument study of its thermal conductivity
Authors: Sinitsin A. A. , Soloveva O. V. , Akhmetova I. G. , Vankov Y. V. , Zakrevskaya L. V. , Ananiev M. S. , Shakurova R. Z.
Published: January 2023

THE PURPOSE. One of the directions of energy saving and energy efficiency improvement is the reduction of consumption of fuel and energy resources. A large amount of thermal energy is spent on heating buildings and structures during the heating season. To reduce heat losses through the building envelope, various heat-insulating materials with low thermal conductivity are used. The purpose of this research was to study the problem of developing the technology of lightweight concrete based on diatomite rocks, as well as uneven inclusions of filler from microspherical granules arising during its creation, assessing the effect of the presence of zones not occupied by microgranules on the insulating properties of the composite material, as well as determining the effect of the volume content of microspherical granules on the value of thermal conductivity.

METHODS. In this work, we studied the production of lightweight structural concrete with porous aggregate synthesized from diatomite  rocks of the Vladimir region, as well as the effect of the presence of zones not occupied by microgranules on the insulating properties of the composite material. RESULTS. The results showed that the distribution of microgranules in the matrix has a significant effect on the insulating properties of the composite, and the presence of voids in the material contributes to heat losses and a decrease in the thermal resistance of the material.

CONCLUSION. The technology for obtaining the developed concrete does not differ from the technology for the production of high-class concrete, which allows the use of widely used concrete equipment.
Environmental characteristics of thermal utilization of waste with external and internal supply of thermal energy
Authors: Demin A. V. , Demina G. V.
Published: January 2023

THE PURPOSE. Identification of optimal regimes for autothermal and allothermic methods of gasification of plant biomass in terms of energy parameters of generator gases, as well as determination of environmental indicators during subsequent combustion of generator gases to obtain thermal energy.

METHODS. When modeling gasification processes, a nonstoichiometric model was used, based on the assumption that a chemically reacting multicomponent mixture is in a state of thermodynamic and chemical equilibrium, which corresponds to the minimum value of the isobaric-isothermal potential. When modeling the combustion of generator gas in a mixture with air, a kinetic model of a perfectly mixed flow reactor was used and the detailed mechanism of chemical interaction for the C-H-O-N-S reacting system was taken into account. The calorific value of generator gas obtained by steam gasification and external supply of thermal energy is significantly higher than the calorific value of gas obtained by internal supply of thermal energy. However, the values of the energy potential and thermochemical efficiency are very close for both types of gasification.

RESULTS. For plant biomass with a given averaged elemental composition, gasification conditions are determined that increase the degree of conversion of initial materials into generator gas. In particular, for the autothermal gasification method, the maximum calculated values of the energy potential of dry ash-free generator gas and thermochemical efficiency were obtained at an excess air coefficient α ≈ 0.32. For the allothermic gasification method, the maximum calculated values of the energy potential of the generator gas and the thermochemical efficiency correspond to the gasification temperature range T ≈ 1050 -1100 K and the mass fraction of the supplied steam gH2O ≈ 0.217. To ensure these conditions, it will be necessary to supply thermal energy through combustion of ≈ 37 wt. % generator gas. Generator gas produced by the allothermic method has higher energy performance, and the negative impact on the environment during its subsequent combustion is characterized by lower specific CO and CO2 emissions in terms of a ton of reference fuel.
Biocoke from wastewater sludge is an effective substrate for disinfecting Msw polygons and restore soil quality
Authors: Makoev S. O. , Akhmetova I. G.
Published: January 2023

THE PURPOSE. Wastewater treatment and waste disposal of sorbents obtained from residual biomass. Obtaining biocoke from sludge. Ensuring maximum calorific value of raw materials.

METHODS. X-ray phase analysis of ash after burning spent sorbents. Thermogravimetric analysis of biocoke in an oxidizing environment. Elemental analysis evaluation of raw materials and products of municipal solid waste thermal conversion. Experimental analysis of municipal solid waste morphological composition for the municipal district.

RESULTS. Completed experimental studies on the analysis of sewage sludge and an assessment on energy and environmental indicators. The substation of partial replacement of fossil fuels by using municipal solid waste in thermal energy generation. Scheme of wastewatertreatment and application of used sorbents as fuel. In order to clarify the calorific value, experiments were made in a calorimetric bomb which showed that biocoke has a lower calorific value of 11.5 MJ/kg. The calorific value of biocoke was obtained according to the data of a thermal analyzer, which is 8–12 MJ/kg and depends both on the type of initial sewage sludge and on the mode of biocoke preparation.

CONCLUSION. The obtained results make possible to evaluate the effectiveness of biocoke usage obtained by conversion of sewage sludge for the disinfection of MSW landfills and the impact on restoring soil quality.
Axial distribution of gas temperature and sound speed in a pipe with a swirled flame
Authors: Malahov A. O. , Larionov V. M. , Konstantinov N. V.
Published: January 2023

Earlier, an experimental and theoretical study of pulsating combustion in a pipe with a tangential supply of a mixture of propane-butane fuel with air was carried out. It was found that the results of calculating the frequencies of gas oscillations differ significantly from the experimental data. One of the reasons is the hypothetical nature of the axial distribution of the speed of sound in the combustion chamber. In this work, this distribution is found on the basis of calculated and experimental data on the gas temperature at the ends of the pipe.
Generating electricity in a solid oxide fuel cell decarbonization methods
Authors: Filimonova A. A. , Vlasova A. Y. , Kamalieva R. F.
Published: January 2023

THE PURPOSE. Determination of effective methods of carbon dioxide capture and utilization, search for promising solutions and testing of carbon dioxide capture methods at a laboratory facility. The most popular absorption methods of CO2 capture, in which the gas reacts with a liquid absorbent.

METHODS. The laboratory setup includes the CO2 source itself (gas cylinder), an absorber, and a flask with sodium hydroxide solution to analyze absorption efficiency. Efficiency is evaluated by the titrimetric method, where a solution of hydrochloric acid is used as a titrant, phenolphthalein and methyl orange act as indicators.

RESULTS. For the analysis, available absorbents were selected, which are available at most thermal power plants. As a result of a laboratory experiment, it was found that a quicklime suspension of 6% has the highest sorption capacity.

CONCLUSION. The decarbonization of the industrial energy sector is a complex process that requires global changes in fuel policy, namely the transition to carbon-free energy resources. An alternative energy resource is hydrogen energy, but even here carbon dioxide emissions are present. Capture and disposal will help decarbonize the main sources of pollution. Industrial carbon dioxide capture has great potential, which lies in the variety of uses of sorption materials.
Toxicity of carcinogenic pahs in boiler flue gases thermal capacity up to 1 Mw
Authors: Ivanitskiy M. S.
Published: January 2023

THE PURPOSE. In accordance with the new requirements of domestic environmental legislation, technological principles of state regulation of the negative impact of energy enterprises on the environment have been introduced. The established principles of environmental protection activities provide for technological regulation of emissions based on the introduction of the best available technologies, as well as differentiation of state regulatory measures to ensure the environmental safety of thermal power facilities. Within the framework of the current environmental legislation, it is shown that it is necessary to determine emission standards for highly toxic substances that have carcinogenic properties. The main representatives of carcinogenic PAHs found in the flue gases of boilers of low power up to 1 MW are considered.

METHODS. The research methods included the generalization of experimental data and thecalculated assessment of the content of carcinogenic emissions, including benz(a)pyrene in the flue gases of boilers using statistical data processing methods.

RESULTS. The necessity of taking into account the contribution of the harmfulness of carcinogenic PAHs in the system of industrial environmental control at thermal power facilities during the operation of low-power boilers is determined.

CONCLUSION. The results of the study can be used at energy enterprises to implement the requirements of the new environmental legislation in terms of technological regulation of carcinogenic emissions, including for the development of measures to improve environmental performance indicators.
β-arrestin2 Mediates the Arginine Vasopressin-Induced Expression of IL-1β in Murine Hearts
Authors: Yao Na , Guo Beibei , Wang Yuhang , Hu Ying , Zhu Xiaofang , Cao Jiaxin , Liu Yi , Qian Yi , Sang Hua , Zhu Weizhong
Published: January 2023

Background: Circulating levels of arginine vasopressin (AVP) are elevated during cardiac stress and this could be a factor in cardiac inflammation and fibrosis. Herein, we studied the effects of AVP on interleukin-1β (IL-1β) production and the role(s) of β-arrestin2-dependent signaling in murine heart. Methods: The levels of IL-1β mRNA and protein in adult rat cardiofibroblasts (ARCFs) was measured using quantitative PCR and ELISA, respectively. The activity of β-arrestin2 was manipulated using either pharmacologic inhibitors or through recombinant β-arrestin2 over-expression. These experiments were conducted to determine the roles of β-arrestin2 in the regulation of AVP-induced IL-1β and NLRP3 inflammasome production. The phosphorylation and activation of NF-κB induced by AVP was measured by immunoblotting. β-arrestin2 knockout (KO) mice were used to investigate whether β-arrestin2 mediated the AVP-induced production of IL-1β and NLRP3, as well as the phosphorylation of the NF-κB p65 subunitin mouse myocardium. Prism GraphPad software(version 8.0), was used for all statistical analyses. Results: AVP induced the expression of IL-1β in a time-dependent manner in ARCFs but not in cultured adult rat cardiomyocytes (ARCMs). The inhibition of NF-κB with pyrrolidinedithiocarbamic acid (PDTC) prevented the AVP-induced phosphorylation of NF-κB and production of IL-1β and NLRP3 in ARCFs. The deletion of β-arrestin2 blocked the phosphorylation of p65 and the expression of NLRP3 and IL-1β induced by AVP in both mouse hearts and in ARCFs. Conclusions: AVP promotes IL-1β expression through β-arrestin2-mediated NF-κB signaling in murine heart.
Inhibition of SARS-CoV-2 Mpro with Vitamin C, L-Arginine and a Vitamin C/L-Arginine Combination
Authors: Đukić Ivana , Kaličanin Nevena , Sencanski Milan , Pajovic Snezana B. , Milicevic Jelena , Prljic Jelena , Paessler Slobodan , Prodanović Radivoje , Glisic Sanja
Published: January 2023

Background: Drug resistance is a critical problem in health care that affects therapy outcomes and requires new approaches to drug design. SARS-CoV-2 Mpro mutations are of concern as they can potentially reduce therapeutic efficacy. Viral infections are amongst the many disorders for which nutraceuticals have been employed as an adjunct therapy. The aim of this study was to examine the potential in vitro activity of L-arginine and vitamin C against SARS-CoV-2 Mpro. Methods: The Mpro inhibition assay was developed by cloning, expression, purification, and characterization of Mpro. Selected compounds were then screened for protease inhibition. Results: L-arginine was found to be active against SARS-CoV-2 Mpro, while a vitamin C/L-arginine combination had a synergistic antiviral action against Mpro. These findings confirm the results of our previous in silico repurposing study that showed L-arginine and vitamin C were potential Mpro inhibitors. Moreover, they suggest a possible molecular mechanism to explain the beneficial effect of arginine in COVID patients. Conclusions: The findings of the current study are important because they help to identify COVID-19 treatments that are efficient, inexpensive, and have a favorable safety profile. The results of this study also suggest a possible adjuvant nutritional strategy for COVID-19 that could be used in conjunction with pharmacological agents.
Effects of Prolonged High-Fat Diet Consumption Starting at Different Ages on Behavioral Parameters and Hippocampal Neuroplasticity in Male Mice
Authors: Yang Chenxi , Yao Xiuting , Zhang Hongyu , Wang Conghui , Zhao Jingyi , Xu Dan , Xiao Yu , Li Qian , Zhuang Hong , Kang Xiaomin , Sun Congli , Liu Lijie
Published: January 2023

Background: The overconsumption of a high-fat diet (HFD) has been repeatedly blamed as being a possible contributor to the global prevalence of emotional problems in modern society. Our group recently demonstrated the deleterious effect of a chronic HFD throughout adulthood on both emotional behavior and neuroplasticity markers in mice. As a heightened preference for palatable HFDs from the time of the juvenile period (when the brain is particularly vulnerable to environmental insults) is universal among populations around the world, a comparison of the consequences of chronic HFDs starting from juveniles or adults will assist in obtaining better knowledge of the impact that chronic HFDs have on mental health, thus potentially leading to the discovery of more effective strategies for reducing the incidence of psychiatric disorders. Methods: In the present study, male C57BL/6J mice with an initial age of 4 weeks (IA-4 W) or 8 weeks (IA-8 W) were separately assigned to two subgroups and fed either a control diet (CD, 10 kJ% from fat) or HFD (60 kJ% from fat) for 9 months followed by an analysis focused on metabolic, emotional behavioral, and neuroplastic profiles. Results: The results illustrated that, in addition to abnormal glucolipid metabolism and insulin sensitivity, mice on a chronic HFD exhibited increased levels of anxiety and depression-like behaviors and aberrant hippocampal neuroplasticity. When compared with IA-8 W mice, several changes indicating systemic metabolic disturbance and neurobehavioral disorder after chronic HFD consumption were aggravated in IA-4 W mice, accompanied by exaggerated impairments in hippocampal insulin sensitivity and neurogenesis. Conclusions: These results not only provide in vivo evidence that the juvenile stage is a critical period of vulnerability to detrimental effects of HFD consumption on metabolic and neuronal function but also suggest dampened hippocampal insulin signaling as a potential link between prolonged HFD consumption and negative neurobehavioral outcomes. Considering the substantial burden posed by psychiatric disorders and the high prevalence of HFD among youth, these observations are meaningful for raising awareness of the harmful effects of excessive dietary fat intake and developing strategy for preventing mental disorders.
Intraoperative Cortico-Cortical Evoked Potentials for Monitoring Language Function during Brain Tumor Resection in Anesthetized Patients
Authors: Vega-Zelaya Lorena , Pulido Paloma , Sola Rafael G. , Pastor Jesús
Published: January 2023

Background: Cortico-cortical evoked potentials (CCEPs) have been used to map the frontal (FLA) and parietal (PLA) cortical regions related to language function. However, they have usually been employed as a complementary method during sleep-awake surgery. Methods: Five male and two female patients received surgery for tumors located near language areas. Six patients received general anesthesia and the sleep-awake method was used for patients with tumors located near the cortical language areas. We performed motor and somatosensory mapping with CCEPs to identify language areas and we monitored responses during surgery based on the mapping results. Electrocorticography was performed throughout the surgery. Single pulses of 1 ms duration at 5–20 mA were delivered by direct cortical stimulation using one grid at one region (e.g., FLA) and then recording using a second gird at another area (i.e., PLA). Next, reversed stimulation (from PLA to FLA) was performed. The charge density for electrical stimulation was computed. Sensibility, specificity, predictive positive values, and predicted negative values were also computed for warning alterations of CCEPs. Results: Gross tumor resection was achieved in four cases. The first postsurgical day showed language alterations in three patients, but one year later six patients remained asymptomatic and one patient showed the same symptomatology as previously. Seizures were observed in two patients that were easily jugulated. CCEPs predicted warning events with high sensibility and specificity. Postsurgical language deficits were mostly transitory. Although the latency between frontal and parietal regions showed symmetry, the amplitude and the relationship between amplitude and latency were different for FLA than for PLA. The charge density elicited by CCEPs ranged from 442 to 1768 μC/cm2. Conclusions: CCEPs have proven to be a reliable neurophysiological technique for mapping and monitoring the regions associated with language function in a small group of anesthetized patients. The high correlation between warning events and postsurgical outcomes suggested a high sensitivity and specificity and CCEPs can be used systematically in patients under general anesthesia. Nevertheless, the small number of studied patients suggests considering these results cautiously.
Outcomes of Patients Undergoing Rotational Atherectomy with Intra-Aortic Balloon Pump Support in Patients with Multivessel Disease and Low Left Ventricular Ejection Fraction
Authors: Hu Hao , Guo Zhiqing , Wu Jiawei , Ma Likun
Published: January 2023

Background: The aim of the present study was to investigate whether intra-aortic balloon pump (IABP) support was associated with better outcomes after rotational atherectomy (RA) in patients with multivessel disease and low left ventricular ejection fraction (LVEF). Methods: Between January 2015 and December 2021, 596 consecutive patients with severely calcified coronary lesions who underwent elective RA were retrospectively enrolled. Of these, a total of 156 patients were included in this study based on the propensity score matching and divided into two groups according to elective IABP insertion (IABP group, n = 80) or no insertion (non-IABP group, n = 76) before the RA procedure. The primary endpoints were procedural success and major adverse cardiovascular events (MACE) before discharge. The secondary endpoints were mortality and readmission due to heart failure (HF) during 90-day and 180-day follow-up. Results: 77 of patients (96.3%) in the IABP group and 72 of patients (94.7%) in the non-IABP group got procedural success (p = 0.714), separately. We had not observed significant differences in periprocedural complications except for less frequent hypotension in the IABP group (p < 0.001). In-hospital MACE occurred in 7.5% of patients who received IABP support, which was significantly lower compared to the non-IABP group (p = 0.002). In addition, the cumulative incidence of readmission due to HF was also significantly lower in the IABP group during the 90-day (p < 0.001) and 180-day (p = 0.004) follow-up. However, there were no significant differences between groups regarding the incidence of all-cause mortality. Conclusions: The present study suggests the important role of IABP support in improving the outcomes of patients after RA if multivessel disease and low LVEF are anticipated. Prophylactic IABP implantation was related to a lower incidence of in-hospital MACE, and readmission due to HF within 90-day and 180-day follow-up without significant impact on the procedural success and all-cause mortality.
PENGEMBANGAN PROSES SAPONIFIKASI DAN KONDISI REVERSED PHASE-HPLC-MWD PADA ANALISIS KOLESTEROL TELUR DARI METODE STANDAR AOAC 994.10:2012
Authors: Faridah Didah Nur , Maslukhah Yulina Lailatul , Anggraeni Ririn , Lioe Hanifah Nuryani
Published: January 2023

Penentuan komposisi fase gerak, efisiensi waktu analisis, kromatogram yang bagus dan kehandalan instrumen perlu dipertimbangkan sebelum pengembangan metode analisis kolesterol menggunakan Reversed Phase-HPLC-Multiwavelength Detector (MWD). Konsentrasi KOH dan waktu saponifikasi diketahui berpengaruh terhadap kadar kolesterol yang diperoleh. Tujuan penelitian ini yaitu untuk mengembangkan metode kondisi RP-HPLC-MWD sebelum digunakan untuk analisis kolesterol, menguji kehandalan instrumennya, serta mengembangkan metode analisis kolesterol dalam telur ayam broiler dengan mengkombinasikan konsentrasi KOH dan waktu saponifikasi, pada suhu 80°C. Kombinasi acetonitril:metanol sebagai fase gerak (80:20, 20:80, 10:90, 0:100 v/v) dengan laju alir 1.2 mL/menit dan fase gerak 0:100 dengan laju alir 1.0 dan 0.8 mL/menit pada pada λ= 200, 205, 210 nm. Konsentrasi KOH dan waktu saponifikasi yang digunakan untuk pengembangan metode analisis kolesterol telur ayam yaitu 5 dan 10 % selama 15, 30, 45 menit. Kondisi RP-HPLC-MWD yang terpilih yaitu komposisi fase gerak metanol 100%, dengan laju alir fase gerak 1.0 mL/menit, λ= 205 nm. Instrumen ini mempunyai linieritas yang bagus, R2 = 0.9991. Limit deteksi dan kuantifikasi instrumen ini secara berurutan yaitu 5 dan 10 μg/mL. Konsentrasi KOH sebesar 10% (b/v) dan waktu saponifikasi selama 15 menit menghasilkan kadar kolesterol tertinggi dengan presisi yang bagus.

 
BATAN PERSONAL DOSE EQUIVALENT Hp (10) AND Hp (3) INTERCOMPARISON RESULTS AT 2018 & 2019
Authors: Firmansyah Assef Firnando , Firmansyah Okky Agassy , Melinda Rizka Sarah
Published: January 2023

One of the methods to ensure the quality of a laboratory is participating in an intercomparison activity. For the dosimetry laboratory network in Indonesia, the intercomparison activity is managed by the Secondary Standard Dosimetry Laboratory (SSDL) Jakarta. This paper describes the intercomparison among processing laboratory for personal dose equivalent Hp(10) and Hp(3) using thermoluminescent dosimeter (TLD)/films in 2018 & 2019. The SSDL Jakarta irradiated packages of participant's TLDs/films with Cs-137 and X-rays at a specific equivalent dose. The irradiated dosimeters were sent back to the participants by mail, and then the result was sent to the SSDL Jakarta for evaluation. The evaluation was carried out using the trumpet curve under the International Atomic Energy Agency (IAEA) publication. The results obtained for the 2018 intercomparison show the success rates of 98%, and 2% were outside the acceptable range, whereas for the 2019 Intercomparison, the success rates were 96% and 4% outside the acceptable range. The potential failure of reading the dose value was in the film dosimeter/badge. For those recent two years of intercomparison activities, the success rate was more than 95%. This result of the intercomparison activity showed the excellent quality of the personal dose equivalent Hp(10) and Hp(3) measurement in Indonesia.
MANAJEMEN RISIKO PADA LAYANAN DINAS KEPENDUDUKAN DAN PENCATATAN SIPIL KOTA SURAKARTA DI ERA NORMAL BARU
Authors: Fahma Fakhrina , Sutopo Wahyudi , Prakoso Ferry Dimas
Published: January 2023

Perkembangan krisis kesehatan saat ini berdampak pada risiko yang dihadapi sektor publik semakin beragam. Berdasarkan PP No.60 Tahun 2008 tentang Sistem Pengendalian Intern Pemerintah (SPIP), lembaga negara/pemerintah wajib menerapkan manajemen risiko. Penelitian ini bertujuan untuk mengidentifikasi dan mengelola risiko dalam melaksanakan pelayanan pada Dinas Kependudukan dan Pencatatan Sipil (Disdukcapil)  Kota Surakarta di era kenormalan baru sehingga memiliki standar manajemen risiko yang dapat diandalkan dan diimplementasikan secara efektif. Pendekatan yang dilakukan yaitu berdasarkan kerangka kerja ISO 31000 yang meliputi : komunikasi dan konsultasi, penetapan konteks, penilaian risiko, serta penanganan risiko. Tahap komunikasi dan konsultasi  serta penetapan konteks dilakukan melalui Forum Group Discussion (FGD) dengan pemilik risiko yaitu segenap pimpinan Disdukcapil.  Sedangkan tahap penilaian risiko dilakukan dengan menggunakan metode House Of Risk (HOR). House Of Risk (HOR) adalah suatu model yang didasarkan pada kebutuhan akan manajemen risiko yang berfokus pada tindakan pencegahan untuk menentukan penyebab risiko yang menjadi prioritas dan kemudian akan diberikan tindakan mitigasi risiko. Dari hasil identifikasi risiko pada layanan Disdukcapil Kota Surakarta pada era kenormalan baru, baik secara offline maupun online didapatkan 15 risk event dan 28 risk agent. Setelah dilakukan analisis menggunakan metode HOR Fase 1 dan konsep pareto, dari seluruh risk agent terpilih 10 yang akan diberikan tindakan preventif. Dari evaluasi atas 10 risk agent yang terpilih, didapatkan 19 tindakan preventif. Dengan menggunakan metode HOR Fase 2, dapat diketahui urutan prioritas tindakan preventif yang dapat diterapkan dalam proses penanganan risiko.
IDENTIFIKASI DAN PERHITUNGAN KETIDAKPASTIAN PENGUJIAN VISKOSITAS KARAGINAN MENGGUNAKAN VISKOMETER ROTARI
Authors: Agusman Agusman , Fateha Fateha , Asmanah Asmanah , Ulya Niswatin
Published: January 2023

Viskositas merupakan salah satu karakteristik mutu karaginan yang diprasyaratkan dalam SNI Karaginan 8391-1:2017. Pada pengukuran viskositas tersebut, laboratorium uji dan laboratorium sertifikasi harus melakukan evaluasi perhitungan ketidakpastian pengukuran sesuai yang disarankan dalam SNI ISO/IEC 17025:2017. Tujuan dari penelitian ini adalah untuk evaluasi ketidakpastian pengukuran viskositas karaginan menggunakan viskometer rotari. Pada penelitian ini, sumber ketidakpastian berhasil diidentifikasi menggunakan diagram Ishikawa (cause-effect), dan kontribusi dari tahapan proses terhadap ketidakpastian berhasil dihitung. Sumber ketidakpastian pada pengukuran viskositas karaginan berasal dari tahapan proses penimbangan, pengendalian dan pengukuran suhu, serta dari alat viskometer rotari. Hasil menunjukkan viskometer rotari menyumbang ketidakpastian terbesar dari tahapan lainya, yaitu sebesar 61,59% dari total ketidakpastian gabungan. Hasil perhitungan besaran ketidakpastian gabungan adalah sebesar 0,000063. Hasil uji bahan acuan sekunder yang memiliki viskositas sebesar 71,5 cP, diperoleh ketidakpastian diperluas sebesar ± 0,01 cP. pada tingkat kepercayaan 95% dan faktor cakupan 2.
The legacy of Muslim theologians in the focus of historical analysis of the adaptation of the Islamic legal system to Russian realities
Authors: Mukhametshin R. M. , Kashaf Sh. R.
Published: January 2023

The article deals with historical development of the theological heritage of the Muslim peoples of Russia. Authors attempt to identify features specific to the formation of theological and legal Islamic thought. They research the activity of the important centres of Islamic scholarship in Russia, mainly the Northern Caucasus and the Ural-Volga region. The results reveal the successful adaptation of the legal system as developed for centuries within the framework of the Russian Muslim community as “the northern outpost of the Islamic world” to the realities of modern life. Modern times bring challenges to the spiritual security of the Russian Federation. Among them is global terrorism, as well as attempts to implant ideology historically and traditionally alien to the country into the religious communities of Russia as well as the Islamic Ummah. Within this context, the fatwa-making activity of the Russian muftis is of great importance. Having implemented the theological and legal heritage of Islamic thought into the modern spiritual practice of the Russia's Muslim community, spiritual leaders who stand on the position of moderate Islam have issued and continue the tradition to issue fatwas (decisions). These fatwas are aimed at preserving spiritual integrity, religious values, morality and compliance with religious prescriptions traditional for Islam in Russia. The system of Islamic education as formed in Russia based on unified methodological approaches, which should contribute to training Islamic theologians in Russia.
Jadidism as a new phenomenon in the educational system of Muslims of the Samara Province at the turn of the XIX-XX centuries
Authors: Gumerov M. M.
Published: January 2023

Since the 1880s, an active part of the Muslim intelligentsia has been striving to reform the educational system (the so-called Jadidism) on the territory of the Russian Empire. A Crimean teacher and public figure Ismail Gasprinsky (1851–1914) was at the origins of the spread of the Jadid educational system in Russia. In the future (1880s–1915s), centers of new-fashioned education appeared on the territory of the Volga-Ural region. Despite the fact that there were no such well-known and large-scale Jadid schools in the Samara Province, as, for example, in Kazan or Ufa, a new type of educational institutions starts appearing in some counties and the provincial center of the region. The author attempts a comparative analysis of the program of the Jadid schools of the Samara Province with other well-known new-fangled educational institutions of the Russian Empire. As a result, the author concludes that, for the most part, the Jadid schools of the Samara Province had much in common in educational and methodological approaches with other madrassas of the Russian Empire of this type: they clearly defined the terms of study, introduced secular subjects, carried out the sound method of teaching (Phonics). Moreover, education in native language, classroom teaching and fixed-term system became possible.