bluuebunny/crossref_metadata_2025 huggingface dataset:
The anacardic acid-loaded nanoliposomes improved the anticancer activity in vitro
Authors: Thi Thao Do , Thi Nga Nguyen , Thi Phuong Do , Thi Cuc Nguyen , Ha Phuong Trieu , Thi Thu Ha Dao
Published: February 2024

Anacardic acid accounts for approximately 77% of the cashew nut shell liquid from Anacardium occidentale, which was reported to have anticancer potential. Due to its water insolubility, the compound is hard to absorb leading to less bioavailability. Currently, using nanolipsomes as drug carriers in general and for anacardic acid in particular could be an effective solution. In this research, anacardic acid was incorporated into nanoliposomes by employing the thin-film method. The results showed that the fabricated nanoliposomes with egg lecithin, cholesterol, and DSPE-PEG as components will have higher encapsulatted efficiency when compared with the fomula using soybean lecithin. The obtained anacardic acid nanoliposomes (AAL) present a size of 135.2 nm, a PDI of 0.095, and a negative zeta voltage of -27.9 mV. The AAL nanoparticles were also evaluated for their growth inhibitory capacity on several cancer cell lines by MTT assay. The GI50 (growth inhibition concentration at 50%) values were determined to range from 80.13 µM to 95.29 µM, of which AAL showed the strongest activity on NTERA-2 human cancer stem cells (80.13 µM). The NTERA-2 cell cycle was also significantly arrested at the S phase (19.43%) under treatment with anacardic acid nanoliposomes. This is the first time for AAL reported activity against cancer stem cells. The activity suggests the potential anti-cancer stem cells of anacardic acid nanolposomes.
Resistome and plasmidome in an extensively drug-resistant extra-intestinal pathogenic Escherichia coli isolated from a one-year-old child with respiratory distress syndrome
Authors: Van Anh Nguyen , Thuy Duong Nguyen , Thanh Tam Tran Thi , Quang Huy Nguyen
Published: February 2024

The global health is facing a growing menace of multidrug-resistant and extensively drug-resistant bacteria over time. Genomic plasticity of pathogenic Escherichia coli allows them to continuously develop and acquire genetic elements associated with antibiotic resistance, including resistance to last resort drugs like carbapenems – only used for the treatment of multidrug-resistant bacterial infections. This study aimed at identifying resistome and plasmidomes carrying antibiotic-resistant genes (ARGs) in an extensively drug-resistant extra-intestinal pathogenic E. coli strain XP817 isolated from a one-year-old child with respiratory distress syndrome. Whole genome analysis of strain XP817 revealed 68 ARGs documented in the Comprehensive Antibiotic Resistance Database (CARD). Notably, strain XP817 possessed 12 ARGs and mutations responsible for its extensively drug-resistant phenotype to aminoglycosides (aacC2 and rmtB), tetracycline (tetA and tetR), bleomycin (bleMBL), chloramphenicol (mdtM), penicillin and cephalosporin (blaCTX-M-27 and blaAmpC), fluoroquinolones (gyrA and parC), macrolide (mphA) and carbapenem (blaNDM-1). Furthermore, five plasmids carrying seven ARGs originated from E. coli strain ECCHD184 (carrying mph(A)) and other species of Enterobacteriaceae family including Enterobacter hormaechei (carrying blaNDM-1 and bleMBL), Proteus mirabilis (carrying tet(A) and tetR), Raoultella ornithinolytica (carrying blaCTX-M-27) and Klebsiella pneumonia (carrying aacC2) were detected. In conclusion, our study underlines the crucial role of the ARG dissemination via horizontal gene transfer in E. coli as well as in the Enterobacteriaceae family.
Expression of global consensus non-structural protein 1 (NS1) of dengue virus serotypes 1 and 2 in Nicotiana benthamiana
Authors: Le Nguyen Cu , Ngoc Luong Nguyen , Quoc Trieu Tuong , Hoang Loc Nguyen
Published: February 2024

Dengue viruses, which consist of four distinct serotypes, belong to the Flavivirus family, one of the most important arthropod-borne pathogen groups for humans. Vietnam is among the tropical countries that have endemic dengue outbreaks, and in 2022, the number of infections as well as fatal cases reached a record high, causing a great economic burden to the public health system. Although all four dengue serotypes have been circulating in Vietnam, serotypes 1 and 2 have been dominating in the last few decades. Since most dengue clinical complications result from secondary infection with a different serotype from the first infection, prior knowledge of the proportion of a population having seropositive to a certain serotype is very crucial for public health policy makers. The absence of comprehensive and regular serological epidemiological surveys in Vietnam has impeded progress in surveillance and the implementation of effective preventive measures. To facilitate research into dengue treatment and diagnosis, we created two synthetic, codon-optimized genes encoding for global consensus non-structural protein 1 (NS1) from dengue serotypes 1 and 2. We expressed these genes in Nicotiana benthamiana using the agroinfiltration technique. Western blot using Dengue patients’ sera indicated that the target proteins were expressed, likely in both mono and multimeric forms. Our results indicated that N. benthamiana is a good alternative to other methods of producing recombinant NS1.
Supporting functions of oligochitosan on soybean seed germination under normal and salinity stress conditions
Authors: Ngoc Lam Pham Nguyen , Tam Nghi Tran Duong , Quang Phat Do , Bang Tuyen Nguyen Thi , Huyen Tram Nguyen Ngoc , Thi Hoang Xuan Lan , Phuong Thao Nguyen
Published: February 2024

Soybean is considered one of the important sources of oil and proteins worldwide. Nevertheless, the cultivation of soybeans is challenged by the threats of saline intrusion. Chitosan, a product derived from the shells of crustaceans such as shrimp, has been reported as a non-toxic biodegradable biopolymer that can minimize adverse impacts of salinity stress on plant growth. This study was to investigate the supportive activities of chitosan on germination under salinity stress of the local soybean cultivar MTD885-3. The assessment was conducted by pre-soaking soybean seeds in either distilled water, a commercial solution for seed germination, gibberellic acid 30 ppm, or oligochitosan solutions (500 ppm, 1000 ppm, and 2000 ppm), before allowing them to germinate in NaCl solution at different concentrations (0, 100, and 200 mM). As expected, soybean sprout emergence and growth were more adversely affected following the application of higher NaCl concentration. The pre-treatment of soybean seeds in oligochitosan solutions of 500 and/or 1000 ppm could enhance hypocotyl and radicle growth under both non-stressed and salinity conditions. Furthermore, seed pre-soaking with 1000 ppm oligochitosan could confer certain benefits for the soybean sprouts exposed to 200 mM NaCl treatment, which were also evidenced by shorter Mean Germination Time, higher Germination Index, and Coefficient of Velocity of Germination values. These findings indicate the practical application of chitosan in supporting the early growth of germinated seeds under osmotic stress conditions such as salinity.
Prácticas de inclusión sexual implementadas en la Institución Educativa Nuestra Señora Del Carmen en la zona rural del municipio de Canalete del departamento de Córdoba
Authors: Díaz Cortes Sergio
Published: February 2024

Este estudio tuvo como propósito entender las estrategias de inclusión sexual adoptadas por la Institución Educativa Nuestra Señora del Carmen en el área rural de Canalete, Córdoba. Para este propósito, se utilizó una metodología cualitativa basada en el enfoque etnográfico. Se llevaron a cabo entrevistas semiestructuradas con estudiantes y grupos focales con docentes, con el objetivo de discernir sus conocimientos en cuanto a inclusión de género y salud sexual y reproductiva. También se estudiaron los métodos pedagógicos empleados para instruir sobre la diversidad sexual en la institución y se exploraron las percepciones de estudiantes y docentes acerca de la diversidad sexual, inclusión de género y sexualidad. El grupo de estudio incluyó a 18 estudiantes de ambos géneros, con edades comprendidas entre 14 y 22 años del décimo grado, y 5 docentes de ambos géneros, con edades entre 28 y 50 años, todos de la Sede Central. Los estudiantes fueron agrupados en parejas para profundizar en sus perspectivas; se seleccionó un grupo focal de docentes y se examinaron documentos institucionales, como planes de mejora y estrategias relacionadas con la inclusión de género. Las conclusiones revelan que existen malentendidos en las percepciones sobre diversidad sexual en este centro educativo rural, destacando confusiones en la terminología y un inadecuado entendimiento de los conceptos asociados a la diversidad sexual.
Prácticas Educativas Familiares en el contexto rural de la educación inicial colombiana
Authors: Osorio Arrieta Yan
Published: February 2024

La relación entre la familia y la escuela en contextos rurales está profundamente influenciada por las características únicas de estas comunidades, incluyendo la proximidad geográfica, los vínculos comunitarios, las tradiciones arraigadas y la economía local. Esta relación única puede ser aprovechada para enriquecer la experiencia educativa de los estudiantes y fortalecer los lazos entre la escuela, la familia y la comunidad. De modo que, este artículo científico tiene el propósito de reconocer los elementos centrales del apoyo familiar en el entorno rural y su impacto en el desempeño académico y la convivencia de los estudiantes del nivel de educación inicial. Por ello, se emplea una metodología cualitativa fundamentada en un diseño participativo, mediado por las técnicas de observación participante y análisis de contenido que,  se erigen como una valiosa alternativa para comprender las interacciones entre los padres y la escuela, identificar los factores que las condicionan o influyen, abordar la falta de apoyo parental hacia la educación de sus hijos,  caracterizar  las familias y su entorno sociocultural, definir elementos centrales de la experiencia mediante una línea temporal y el análisis de los saberes emergentes del proceso de apoyo familiar, así como sus contribuciones a una convivencia escolar saludable. En los resultados, se presenta la sistematización de la experiencia educativa que impulsa la creación y el discernimiento crítico de aquellos que participan en ella, concluyendo en la importancia de dar continuidad y fortalecer las relaciones entre los tres pilares esenciales: madres/padres, estudiantes y docentes-escuela, subrayando la necesidad de continuar y reforzar estas interacciones para un desarrollo educativo más completo.
Radiografía espacial de la violencia sexual a la población femenina en el espacio público de la ciudad de Montería
Authors: Pantoja Escobar Paulina , Agamez Calderón Danilo , Puerta Aviles Oscar
Published: February 2024

Cada día en las ciudades se presentan numerosos casos de delitos que atentan contra la integridad de las personas, tanto física como emocionalmente, en el caso particular de estudio, los delitos sexuales donde mayoritariamente las victimas corresponde a población femenina , siendo sometidas a diferentes actos de agresión sexual de manera verbal, física y/o visual en entornos donde desarrollan sus actividades diarias, viviendo experiencias negativas en el espacio púbico derivado en sensaciones de inseguridad, rechazo o temor en algunos lugares, afectando el goce y disfrute de los mismos. Por tal motivo, surgió el interés desde el ámbito geográfico por evaluar la percepción que tienen las mujeres sobre los espacios públicos de Montería frente a la violencia sexual. En el desarrollo de la investigación, se aplicaron entrevistas y encuestas con la ayuda de un geoformulario web georreferenciado, así mismo, talleres participativos, posteriormente se espacializaron los lugares topofóbicos derivados de la violencia sexual utilizando el método cartográfico y, finalmente, se caracterizaron los lugares percibidos como inseguros de acuerdo con las experiencias vividas por el sexo femenino. En los resultados se indica que, cinco (5) de cada diez (10) mujeres han sido víctimas de violencia sexual en el espacio público de la ciudad de Montería, de igual forma, las mujeres sienten temor de ser víctima de violencia sexual en el centro de la ciudad, seguido de las vías, paradero de buses y parques, en igual forma, se detectaron 9 lugares donde las mujeres refirieron predominantemente haber experimentado incidencias de violencia sexual, distribuidos geográficamente en el centro, sur y norte de la ciudad de Montería.
Análisis de las modalidades y prevalencia del acoso universitario en la Facultad de Ingenierías de la Universidad de Córdoba: un enfoque en el acoso sexual, coacción sexual y coacción económica
Authors: Espitia Cleto Luisa , Echeverri Flórez Heidi , Oyola Mendoza Jorge
Published: February 2024

Este artículo presenta los resultados de un estudio llevado a cabo en la Facultad de Ingenierías de la Universidad de Córdoba, centrado en la identificación y caracterización del acoso universitario. El estudio se enfocó en identificar y caracterizar el acoso universitario, incluyendo el acoso sexual, la coacción sexual y la coacción económica. Además, se buscó determinar la prevalencia de estas conductas, los actores involucrados, las posibles correlaciones de género y la frecuencia con la que se presentan. La investigación adoptó un enfoque transversal, cuantitativo y descriptivo, contando con la participación de 192 estudiantes procedentes de cinco programas académicos dentro de la Facultad de Ingenierías. Los datos fueron recopilados mediante un cuestionario en línea, y posteriormente fueron analizados mediante técnicas y métodos estadísticos para obtener información significativa y útil. Los resultados obtenidos son reveladores. Se identificó una clara correlación entre el género y las experiencias de acoso y coacción sexual, con un número significativamente mayor de denuncias por parte de las mujeres. Los perpetradores de estas conductas son principalmente compañeros de estudio y profesores, lo que plantea cuestiones críticas en términos de la seguridad y el ambiente de aprendizaje en la Facultad de Ingenierías. La mayoría de las personas que las experimentaron optaron por no buscar asistencia ni reportar los incidentes a las entidades de control e investigación pertinentes. Esta reticencia plantea cuestiones adicionales sobre el apoyo disponible para las víctimas de acoso en el ámbito universitario. En general, este estudio es una contribución importante al campo del acoso universitario y proporciona información valiosa para futuras investigaciones y el diseño de políticas.
Estilos de aprendizaje y videojuegos educativos como refuerzo en el aprendizaje de Metodología de la Investigación en estudiantes de pedagogía
Authors: Rojas Bello Rogel , Martínez Cruz Francisco , De Jesús González Teresa
Published: February 2024

El desarrollo informático ha impulsado la evolución de los videojuegos convirtiéndolos en una industria en constante crecimiento y un valioso recurso tecnológico en el ámbito educativo. Numerosas investigaciones han destacado su efectividad en espacios de aprendizaje, demostrando ser un factor motivacional para todas las edades. En particular, en la enseñanza de asignaturas como Metodología de Investigación, resulta relevante implementar estrategias que estimulen el interés y entusiasmo de los estudiantes. Además, ya que las personas en general no aprenden de la misma manera, debe partirse de los planteamientos teóricos de estilos de aprendizaje de los discentes, que está relacionado con la manera en que estos estructuran los contenidos, utilizan conceptos, descifran la información, resuelven las situaciones problemáticas y, eligen, formas de representación. Este estudio se enfocó en identificar y analizar los estilos de aprendizaje y las opiniones de los estudiantes de Metodología de Investigación sobre el uso de videojuegos educativos en una universidad pedagógica de República Dominicana. El estudio es de enfoque cuantitativo de alcance exploratorio-descriptivo, utilizando el test de inventario de estilos de aprendizaje de David Kolb y evaluando las opiniones hacia los videojuegos de una muestra de 24 discentes. Los resultados revelaron una mayor prevalencia del estilo divergente, seguido en menor medida por los estilos asimilador, acomodador hasta convergente. Por otro lado, se evidenció que el uso de videojuegos son una herramienta potencialmente beneficiosa para la enseñanza-aprendizaje de la asignatura Metodología de la Investigación, pues despierta interés y aceptación por parte de los participantes, evidenciado en que la mayoría de los participantes opinan, por medio de un cuestionario, que están de acuerdo en que los videojuegos resultan adecuados y divertidos cuando son usados como recurso en la mencionada asignatura, además los estudiantes expresan que implementarían los videojuegos en las clases con sus futuros estudiantes.
Effect of age at first conception as a selection criterion on growth and carcass traits in Nellore cattle
Authors: Brunes Ludmilla Costa , Baldi Fernando , Costa Marcos Fernando Oliveira e , Lobo Raysildo Barbosa , Lopes Fernando Brito , Magnabosco Cláudio Ulhoa
Published: February 2024

Abstract The aim was to identify predictive traits of relatively easy measurement and which can be recorded early in life (age at first conception - AFCo), besides estimating its genetic correlations with growth and carcass traits in Nellore cattle. Age at first conception was considered the age at which the female had the first positive diagnosis for pregnancy. The estimation of (co)variance components and genetic parameters was performed using a linear animal model in two-trait analysis. The estimates of heritability were moderate, enabling genetic selection for growth-, carcass-, and sexual precocityrelated traits. The genetic correlation obtained between AFCo and age at first calving (AFCa) was high (0.88), indicating the feasibility of using AFCo as a selection criterion for early calving heifers. Genetic correlation estimates between AFCo and AFCa with weight at 120, 210, 365, and 450 days of age and carcass traits were moderate and negative (-0.33 to -0.62). Thus, genetic selection for animals with early AFCo and AFCa would enhance carcass yield, fat deposition, and growth performance, despite not affecting birth weight or daily weight gain. The results of this study encourage the use of AFCo in Nellore cattle since this trait displayed enough genetic variability in Nellore cattle, and can be used as selection criteria to improve sexual precocity. When the objective of genetic selection is to increase heifer sexual precocity, we could use the first trait as a criterion, as the measurement of this trait occurs at a lower AFCa.
Comparison of seven different RT-qPCR for diagnostic of Foot-and-Mouth disease virus
Authors: Fonseca Junior Antonio Augusto , Laguardia-Nascimento Mateus , Ferreira Amanda Petrina Scotá , Silva René Ribeiro da , Rivetti Júnior Anselmo Vasconcelos , Camargos Marcelo Fernandes
Published: February 2024

Abstract The prompt and accurate diagnosis of foot-and-mouth disease outbreaks is crucial to curb the swift transmission of its causative agent, the foot-and-mouth disease virus (FMDV), which poses a substantial threat to the nation’s livestock. This study aimed to perform a comparative analysis of various RT-qPCR methods for the detection of FMDV. The methods evaluated for the 3D region demonstrated similar sensitivity and specificity. Nevertheless, noticeable distinctions emerged in samples with low RNA concentration. While these methods can be interchangeably utilized with consistent outcomes when handling a large number of samples sent to the laboratory to pinpoint an outbreak, minor variations may assume significance when working with a limited quantity of samples containing low FMDV RNA copies.
Grau de cumprimento das boas práticas de fabricação e perfil microbiológico de linguiças frescas mistas
Authors: Charão Gabriel Nunes , Radünz Marjana , Sawitzki Maristela Cortez , Molina Paulo Duran , Gandra Tatiane Valente Kuka , Mello Jozi Fagundes de , Gandra Eliezer Avila
Published: February 2024

Resumo Boas Práticas de Fabricação nas agroindústrias são necessárias para controlar a multiplicação de microrganismos e prevenir a ocorrência de doenças veiculadas por alimentos. Dentre os diversos alimentos que podem ser contaminados pela manipulação intensiva, destacam-se os produtos cárneos, como a linguiça frescal. Com base no exposto, objetivou-se avaliar o nível de contaminação de linguiças frescais produzidas no município de Alegrete (RS) no âmbito da fiscalização do SIM/SISBI entre 2014 e 2016 e correlacionar ao atendimento das Boas Práticas de Fabricação (questionários, orientações e treinamentos). Amostras regulares foram coletadas em 10 estabelecimentos da cidade e testadas para coliformes termotolerantes, Clostridium sulfito redutor, Staphylococcus coagulase positiva e Salmonella spp. A quantificação microbiana de coliformes termotolerantes, Clostridium sulfito redutor, Staphylococcus coagulase positiva e Salmonella spp. diminuiu significativamente, indicando que as intervenções contribuíram para melhorar o perfil microbiológico da linguiça frescal produzida na cidade.
Comparison of the amount of aqueous flare between laser photometry and subjective evaluation techniques in dogs undergoing phacoemulsification
Authors: Andrade Alexandre Lima de , Conceição Luciano Fernandes da , Morales Adriana , Piso Dunia Yesela Trujillo , Tuboni Laís Tieme , Laus José Luiz
Published: February 2024

Abstract This study aimed to compare the quantification of aqueous flares using laser photometry and subjective clinical determination after phacoemulsification through the V-prechop nucleodissection technique in dogs. Forty-three dogs of different breeds, males and females, aged 3-10 years, with mature (G2, n = 22) and immature (G1, n = 21) cataracts, were included. After surgery, the patients were evaluated weekly for aqueous flares (using laser flare photometry) and clinically evaluated using slit-lamp biomicroscopy over different periods. Intraocular inflammation was more evident in patients with stage G2 disease than in those with stage G1 disease. Over time, it regressed in most animals, persisting to a mild degree in three animals by the end of the observation period. Statistical analyses revealed key differences between the groups in the immediate postoperative period and after 30 days of observation. “Aqueous flare” (ph/ms), quantified using laser flare photometry, was higher in the operated eyes of both groups (G1 and G2). However, a significant difference was observed in the immediate postoperative period and at 45 and 30 days in groups G1 and G2, respectively. Furthermore, when comparing the operated eyes of each group, a significant difference was observed in the preoperative period and 60 days postoperatively; the mean values were always higher in the G2 patients (G1-preop = 25.5 ± 11.4 ph/ms and G2-preop = 45.7 ± 17.7 ph/ms; G1-60d = 23.4 ± 8.9 ph/ms and G2-60d = 39.8 ± 13.4 ph/ms). In conclusion, laser cell and flare photometry showed higher accuracy in evaluating aqueous flares than clinical evaluation based on scores during the postoperative period in phacoemulsification by V-prechop nucleodissection. The quantitative values of flares obtained using this non-invasive method may also be used to evaluate other nucleodissection techniques in phacoemulsification.
Effect of Mentha piperita essential oil in the conservation of refrigerated tambatinga hybrid fish meat
Authors: Pretto Alexandra , Lopes Jane Mello , Marinho Iara Reis , Doihara Izumy Pinheiro , Costa Thaisa Sales , Teixeira Claudener Souza , Monteiro Odair dos Santos
Published: February 2024

Abstract The search for safer foods has led to increased research attention to discover natural alternatives to synthetic additives that are used in the food industry. Natural preservatives, such as essential oils (EOs) from plants, could increase fish conservation and even positively affect human health. Therefore, the objective of the study was to evaluate the effect of Mentha piperita EO on the physicochemical characteristics and concentration of microorganisms in chilled tambatinga (Colossoma macropomum × Piaractus brachypomum) meat. Mentha piperita EO was prepared at three concentrations (0%, 0.25% and 0.50%) in a solution containing distilled water, propylene glycol and Tween. The meat samples remained immersed in this solution for 60 min; then, they were packed in plastic packages and stored under refrigeration (± 0.4 °C) for 14 days. During this storage, pH, total volatile nitrogenous bases (TVB-N), peroxides, thiobarbituric acid reactive substances (TBARS) and counts of strict and facultative aerobic mesophilic microorganisms were determined. The major constituents found in M. piperita EO were geranial (32.28%), neral (18.64%) and geranic acid (6.98%). None of the EO concentrations affected TVB-N, but there were some changes to the pH. Both 0.25% and 0.50% EO reduced the formation of peroxides and TBARS. The growth of microorganisms was reduced by treatment with 0.50% EO. Based on the findings, 0.50% EO was more effective in reducing the deterioration of meat kept refrigerated for up to 14 days.
Distribution of coronary arteries and histopathological analysis of three-toed sloth (Bradypus variegatus) heart
Authors: Albuquerque Priscilla Virgínio de , Torres Sandra Maria de , Mesquita Emanuela Polimeni de , Nascimento Júlio Cézar dos Santos , Ribeiro Apolônio Gomes , Evêncio Neto Joaquim , Andrade Gilcifran Prestes de , Amorim Júnior Adelmar Afonso de , Amorim Marleyne José Afonso Accioly Lins
Published: February 2024

Abstract The three-toed sloth (Bradypus variegatus) has been a victim of disorderly human interventions, leading to an increase in accidents and diseases for the species. This study aimed to provide a description of the coronary arteries and to high light the histopathological findings in the sloth’s heart. This information should be beneficial for medical clinics dealing with these species. Eighteen B. variegatus specimens were dissected after natural death. Fifteen of them, comprising five adult males, nine adult females, and one juvenile, were fixed with formaldehyde and preserved in saline solution. In two males and one female, red-coloured latex was injected through the left common carotid artery to make the coronary arteries more visible. In the female, blue-coloured latex was also injected through the right external jugular vein to aid in arterial identification. The chests were opened to evaluate and extract the heart for a detailed description of the coronary arteries. For histopathological analysis, histological slides were prepared from four hearts collected from four animals (three adults and one juvenile). Arterial analyses revealed that sloths possess two coronary arteries: one on the right and one on the left side, each of which supplies blood to their respective surfaces. The heart is composed of the endocardium, myocardium, and epicardium, similar to mammals in general. However, necrosis of endocardial tissue and cardiac muscle fbres, as well as myxomatous degeneration of valves and thrombi in vascular lumens, were observed. These necrotic events, more extensive in nature, are related to infarctions, while the more subtle ones may be associated with stressful situations experienced by the individuals.
Sujeitos históricos e ensino sob a ótica de Eduardo Coutinho: proposta para a formação de professores de história
Authors: Perinelli Neto Humberto , Paziani Rodrigo Ribeiro
Published: February 2024

Resumo O presente trabalho apresenta reflexões sobre as contribuições oportunizadas pelos filmes de conversação de Eduardo Coutinho para delineamento de reflexões associadas ao conceito de sujeito histórico, a ser mobilizado no ensino de história. Tal pesquisa apresenta abordagem qualitativa, natureza aplicada e explicação, mediante emprego de análise bibliográfico, análise documental e observações sistemáticas, segundo perspectiva do tipo ex-post-facto. Os filmes de Coutinho apresentam mulheres, velhos, negros, pobres, periféricos e nordestinos, de modo a tratar com significância suas experiências de vida. A apropriação pedagógica desses filmes é pertinente para construção de processo formativo que se pauta pela abordagem de sujeito histórico a partir de concepções como as dos excluídos/subalternos/de baixo e que é voltado para professores que lecionam História na Educação Básica.
TUTORÍAS UNIVERSITARIAS EN PERÍODOS DE INTERRUPCIÓN ACADÉMICA: UN RELATO DESDE LA EXPERIENCIA
Authors: G. Díaz Hedbenhard
Published: February 2024

RESUMEN Las crisis sociales y la pandemia por COVID-19 representan períodos de interrupción académica que han impactado en el aprendizaje de la educación superior. Ante este panorama, las tutorías universitarias adquieren relevancia como una estrategia para poder afrontar estas crisis y permitir el intercambio de experiencias y emociones. El objetivo de este reporte consiste en presentar una estrategia tutorial diseñada entre los años 2019 y 2020, en el contexto de un programa de acompañamiento académico y psicoeducativo de una universidad estatal de Chile. Esta estrategia consta de seis fases: (1) Encuentro inicial; (2) Diagnóstico; (3) Planificación; (4) Implementación; (5) Evaluación; (6) Cierre del proceso. El desarrollo de esta propuesta demostró la importancia de las emociones, el diálogo y la valoración experiencial del estudiante en su proceso de aprendizaje y adaptación a la universidad. Asimismo, entrega un marco de acción para el acompañamiento académico y psicoeducativo ligado a los programas de tutorías universitarias.
INDEPENDENT ACCREDITATION IN KYRGYZSTAN: STATUS AND PROBLEMS
Authors:   Bishkek Humanities University named after K. Karasaev, Musaev Abdylda
Published: February 2024

In the article, the author addresses the topic of an independent accreditation system in the Kyrgyz Republic, which contributes to improving the quality of education, conducts an independent assessment of educational organizations and educational programs for compliance with criteria and procedures, encourages the development of educational organizations, and most importantly, promotes the recognition of educational documents and qualifications of the Kyrgyz Republic in the world educational space. The author focuses on both the positive aspects of accreditation and the existing shortcomings associated with the recent beginning of the formation of the Institute of independent accreditation in our Republic.
APPLYING OF INFORMATION TECHNOLOGIES IN THE PROCESS OF TEACHING LANGUAGES
Authors:   Kyrgyz National University named after J. Balasagyn, Akhmetova Nurlan , Ismailova Sholpan ,   Kazakh National University named after Al-Farabi
Published: February 2024

The modern approach to education is characterized by the formation of a number of competencies (both professional and universal) necessary for the implementation of a full- fledged professional activity. Information competence is one of such skills in demand today. The article discusses methods, ready-made Internet resources and services based on the use of information and communication technologies in the process of teaching languages. The characteristics of such tools as electronic portfolio, Kahoot quizzes, Hot Potatoes software package, web quest are given. It is advisable to use them at the stage of knowledge control and information search. To implement the principle of visibility, the authors recommend creating a presentation and infographics.
PLACE OF THE COURSE OF GENERAL PHYSICS IN TECHNICAL UNIVERSITIES IN THE CONDITIONS OF DIGITALIZATION
Authors:   International Kuwait university, Babaev Doolotbay , Khaitov Shavkat ,   Kyrgyz-Uzbek International University, Khalmatov Anvar ,   Kyrgyz-Uzbek International University
Published: February 2024

This article discusses the issues of improving the educational process in technical universities based on digitalization. And also, in order to improve students' physical knowledge, work programs and curricula of the general physics course were analyzed. Based on the results of the analysis, methods of organizing methodological recommendations are given. The process of teaching a course in general physics at technical higher education institutions was studied using digitalization methods for the education of future engineers. In addition, attention is drawn to the lack of hours when studying the course of general physics in the curriculum of technical areas.
ESSENTIAL ASPECT OF RESEARCH ON THE PROBLEM OF PREPARATION FOR THE PEDAGOGICAL PROFESSION
Authors:   Kyrgyz National University named after J. Balasagyn, Sulaimanova Rahat
Published: February 2024

One of the priority areas of research in the field of education is the issue of professional training of future teachers. The growing interest of researchers in this issue is associated with the emergence of special requirements for the quality of professional education. The requirements are due to the complexity of the teacher's professional activity in modern conditions, the diversity of its context, the change of communication principles, and the ambiguity of its value and semantic foundations. In accordance with this, the article examines the concept of pedagogical training in higher education and its essential aspect, and analyzes several areas of interrelated research.
THE PROBLEMS OF EDUCATIONAL TECHNOLOGIES IMPROVEMENT IN DIGITALIZATION
Authors:   Ministry of Education and Science of the Kyrgyz Republic, Kosobaeva Bakdolot , Tokombaeva Perizat ,   Bishkek Financial Economic Technical School named after A.Toktonaliev, Abdubapova Aizhan ,   "Zhetigen" school-lyceum
Published: February 2024

Along with other subjects of the general education school, the subject of chemistry forms the scientific outlook and personal qualities of the student. The "Regional Development, Digitalization and Child Support Tasks" announced in 2020 are being implemented. It is important to use a pragmatic approach in chemistry education. It is the responsibility of every teacher to make extensive use of elements of teaching technology in accordance with the requirements of the new generation of standards. This article addresses the issues of computerization of the educational process in the context of digitalization. Opportunities for distance learning in the teaching of computer technology to schoolchildren and students, as well as the development of students' independence were highlighted.This article discusses the problems of computerization of educational process in digitalization. It is given the opportunities of using the Computer Technology
AUTOMATION OF THE PROCESS OF SCHEDULING CLASSES IN EDUCATIONAL INSTITUTIONS AND THE DEVELOPMENT OF A MOBILE APPLICATION FOR TEACHERS, STUDENTS AND MANAGERS
Authors:   Kyrgyz National University named after J. Balasagyn, Bayachorova Batygul , Zhumashov Omurbek ,   Kyrgyz National University named after J. Balasagyn, Batyrov Zharkynbek ,   Kyrgyz National University named after J. Balasagyn, Abdalimbaev Bekzhan ,   Kyrgyz National University named after J. Balasagyn, Mamatbekov Sherislam ,   Kyrgyz National University named after J. Balasagyn
Published: February 2024

At the present time of digitalization, one of the pressing issues in the education system is the automation of various processes in the education system, the development and implementation of mobile applications. Based on new software technologies, we have developed a computer program for automating the process of scheduling classes in educational institutions, which includes a convenient mobile application for teachers, students and managers.
THE ROLE OF FAMILY EDUCATION IN THE PROFESSIONAL GUIDE PROCESS FOR SCHOOL GRADUATES
Authors:   Bishkek Humanities University named after K. Karasaev, Abdyrakunova Zhyldyz
Published: February 2024

The effectiveness of a graduate in choosing the right profession depends on the specifics of family upbringing. In the context of socio-economic reform in the Kyrgyz Republic, there is a reluctance of parents to address the issues of child rearing and their personal development. In this regard it was stressed that in the strategic directions of development of Kyrgyzstan until 2040, special attention should be paid to the institution of the family. As the material and psychological difficulties in the family create significant problems in the upbringing of children. The article describes the concept of the family, the impact of the family, folk pedagogy on the career guidance of graduates. The role of the family is highlighted in the career guidance process as well. The article reveals the
PEDAGOGICAL POSSIBILITIES OF KYRGYZ TRADITIONS CUSTOM AND TRADITIONS IN THE EDUCATION OF YOUNG PEOPLE TO DEMOCRACY
Authors:   Kyrgyz National University named after J. Balasagyn, Asipova Nurbubu , Bayalieva Aisuluu ,   Kyrgyz National University named after J. Balasagyn
Published: February 2024

The article presents strategies for changing the social preparation of young people for life in the context of globalization, the need to educate democracy among young people in developing countries and the reflection of these trends in the educational documents of the Kyrgyz Republic. The purpose of the article is, along with the recognition of the political pound and multilevel of the concept of democracy, the disclosure of its social significance in a time society. The key idea of the article is to reveal the pedagogical possibilities of the customs and traditions of the Kyrgyz people in the education of democracy among young people. In this regard, the importance of the education of girls in the Kyrgyz family is stressed, as well as the educational importance of such traditions as favoring in various situations.
GENERAL DIDACTIC FOUNDATIONS OF OPTIMIZATION OF FORMS OF ORGANIZATION OF THE EDUCATIONAL PROCESS IN THE WORKS OF I. BEKBOEV
Authors:   Ministry of Education and Science of the Kyrgyz Republic, Kydyralieva Aitikan
Published: February 2024

The article is dedicated to the great teacher of Kyrgyzstan I. Bekboev. Most of Bekboev's research is based on the forms of organization of the educational process, especially on the problems of improving classroom hours in accordance with the requirements of the time. What should be taught in the subject educational standards of general education schools in Kyrgyzstan in recent years? How to teach? Attempts have been made to rethink these issues within new paradigms, such as competency-based education, selfishness, and cultural motivations. On the basis of these paradigms, the intention to reduce the gap between the student's knowledge and readiness for life is explained in an accessible form. At the same time, the role of the scientist's work in the development of the didactic competence of modern teachers is emphasized.
IMPACT OF PREVIOUS KNOWLEDGE IN CONSOLIDATING NEW TOPICS
Authors:   Kyrgyz National University named after J. Balasagyn, Kongaitieva Suurakan
Published: February 2024

The scientific article defines the influence of previous knowledge on the consolidation of new knowledge. The use of previous knowledge obtained from various sources, materials of personal observations and practical activities should also be carried out in the process of consolidating new knowledge. An important task of using previous knowledge in the process of consolidating new knowledge is to deepen the understanding of old and new knowledge, develop independence, observation and creative activity of students. When using prior knowledge and personal experience, it is important to consistently teach the techniques of this work. There were conclusions that the consolidation stage will be effective only when the student has mastered the previous material well and with the systematic use of previous knowledge.
BASIC APPROACHES TO GENERAL EDUCATION QUALITY MANAGEMENT
Authors:   Kyrgyz State University named after I. Arabaev, Kudaiberdieva Gulmira
Published: February 2024

The need to ensure the quality of education presupposes the improvement of education quality management. Analysis of the state of quality management of general education in the Kyrgyz Republic shows that there are certain opportunities for its improvement. For this, it is necessary to analyze the mechanism for managing the quality of education in a specific educational institution - in a general education school. The article discusses general approaches to managing the quality of education. Based on the study of the researchers' work, the analysis of the systemic, activity-based, qualimetric, technological approaches to the management of the quality of education has been carried out. The personality-oriented approach in this article is considered as a unifying factor for improving the management of the quality of education.
MATERIALS FOR ETHNOPEDAGOGICAL EDUCATION FOR THE WORKS OF CHILDREN'S WRITERS IN PRIMARY SCHOOLS
Authors:   Jalal-Abad State University named after B.Osmonov, Maatazimova Gulzat
Published: February 2024

This scientific article is devoted to the study of scientific and theoretical literature in 3-4 grades of Kyrgyz schools, a collection of best practices, about methods of conducting scientific research by the method of analysis and synthesis, a pedagogical experiment. The textbooks "Literary Reading" analyzed the presentation of the works of children's writers. It should also be noted that a number of criteria are required to analyze the works of the curriculum and grade 3 textbooks. The textbook for 3rd. grades "Literary reading" (authors A. Toktomatov and B. Subanova) analyzes the presentation of the works of children's writers, and also shows the topics according to which literary texts are divided.
ORGANIZATION AND CONDUCT OF EXTRACURRICULAR LEARNING GOALS AND OBJECTIVES
Authors:   Osh State University, Muzulmanov Melisbek
Published: February 2024

Now in the Kyrgyz Republic there are processes that are accompanied by concepts of “globalization”. It is this culture of reading that must resist the “attacks” of mass culture. One of the main factors in teaching, reading skills is the study of kyrgyz literature and extracurricular activities in this subject. Classroom literature and extracurricular reading are inextricably linked, support and complement each other. The article addresses the problems related to extracurricular reading; the characteristics of teaching extracurricular reading, its purposes and goals along with its core paradigms. Extracurricular reading has been given inadequate importance in schools, in rare cases, it is taught in an informal way. This paper discusses the key principles of designing and implementing teaching extracurricular reading.
ANALYSIS OF THE PROBLEM OF RAISING A CHILD IN ACCORDANCE WITH AGE CHARACTERISTICS IN THE FAMILY IN GLOBAL AND RUSSIAN PEDAGOGY
Authors:   Kyrgyz State University named after I. Arabaev, Muratov Abdykerim
Published: February 2024

In the history of pedagogy and education, there are many opinions about the upbringing of children in accordance with their age characteristics. In this article, we compared the opinions expressed by the classics of the history of pedagogy with the traditions of raising children in the Kyrgyz ethnopedagogy in accordance with their age characteristics. From the pedagogy of Ancient Greece, Athens, Sparta to Aristotle, Plato, Socrates, and others.B. Analyzing the work of scientists, K. D., We have dwelt in more detail on the research of Ushinsky. The study has an ethnopedagogical orientation and is dedicated to modern teachers, teachers of schools, educational institutions, and everyone who is related to educational work. The conclusion from our article is that the education of children in accordance with the age characteristics of traditional education was carried out in accordance with the teachings of the global classical pedagogy.
FEATURES OF MATHEMATICAL TRAINING OF STUDENTS OF CHEMICAL SPECIALTIES
Authors:   Kyrgyz National University named after J. Balasagyn, Salieva Gulzhan , Kasymalieva Gulmira ,   Kyrgyz State University named after I. Arabaev, Seytalieva Elmira ,   Kyrgyz State University named after I. Arabaev
Published: February 2024

The article is devoted to the professional orientation of teaching mathematics in higher education. The issues of the professionally applied orientation of this course, the importance of mathematics in the preparation of students of chemical specialties have always been relevant. Research into the problem of a professional orientation was carried out in three aspects: content, methodological, psychological. Paying special attention to the methodological aspect, we consider the professional orientation of training as a basic requirement, as a leading principle of training. Based on the analysis Based on the analysis, we divided the tasks of the mathematics course into four groups: 1) mathematical problems; 2) mathematical problems with chemical content; 3) educational and applied tasks; 4) professionally applied tasks. The meaning of each type of problem is revealed, the stages of their solution are shown. As an example, the introduction of one of the fundamental concepts of mathematics - "derivative" is considered.
KAYUM MIFTAKOV - IS THE FIRST FOUNDER OF KYRGYZ FOLKLORE
Authors:   National academy of science of Kyrgyz Republic, Moldoshova Gulmira
Published: February 2024

This article provides a short excursion to the first sources of Kyrgyz folklore to collect and discuss scientific facts related to oral folk art. Then a complete overview of the life and work of one of the first founders of Kyrgyz folklore Kayum Miftakov is given. Kayum Miftakov from early childhood was interested in and knew well the content of oral folk art of the peoples of Bashkiria and Tatarstan. Accordingly, at one time, Kayum Miftakov made records of oral folk art of the above peoples. From the age of 14 he worked as a hired shepherd for the Kazakhs, which led to the interest and study of Kazakh folklore. Information about the Kyrgyz and the Kyrgyz people in 1912 from Kanatov and Arabaev, who were studying in Ufa at that time. After the information received, Kayum Miftakov decides to move to Kyrgyzstan. (Kyigizstan) At the beginning of his research, Kayum Miftakov spends a lot of time in Talas, Issyk-Kul, and Naryn. He meets and records (writes down) on paper the epic "Manas", several other works relating to the oral folk art of the Kyrgyz people. Summing up, we can say that in this article Kayum Miftakov is characterized as one of the first folklorists of oral folk art of the Kyrgyz people.
SPECIFICITY OF PHONETIC AND GRAMMATICAL DEVELOPMENT OF MEDICAL TERMINOLOGY IN ENGLISH, RUSSIAN, KYRGYZ LANGUAGES
Authors:   Osh State University, Imankulova Tolgonay
Published: February 2024

In the context of accelerating scientific progress, terminology takes on a special meaning. It is a source of information, a tool for mastering the specialty. The conceptual space of any field of science and technology finds its expression in terms. Terminology is a source of information, a tool for mastering the specialty. The need for the formation and formation of scientific terminological systems requires a deep analysis and description of medical terminology as a special subfield of the studied languages, which determines the relevance of the claimed problems. The article discusses the history and basics of medical terminology. Examples of medical terminology in three languages and their origin are given. The author collects and systematizes data on the development and functioning of medical terminology, their classification, theoretical understanding and description.