bluuebunny/crossref_metadata_2025 huggingface dataset:
Estrategias didácticas para la atención en escolares con necesidades educativas especiales durante el Covid-19. Un estudio de revisión en Ecuador
Authors: Intriago-Alarcón Grace Selene , Rodriguez-Zambrano Arturo Damian
Published: December 2022

En el presente artículo se exponen los resultados obtenidos por medio de una revisión documental y bibliográfica de documentos, artículos científicos y tesis sobre las estrategias didácticas para la atención de escolares con necesidades educativas especiales aplicadas durante por Covid 19, 2019-2022.  A pesar de atravesar una era globalizada, la tecnología es una herramienta de aprendizaje que no está al alcance de todos y la interacción por medios digitales supone un desafío aun mayor para los escolares con necesidades educativas especiales. La investigación se realizó en dos fases, la heurística en la cual se obtuvieron los fundamentos teóricos a través de la metodología de revisión documental y bibliográfica y la fase hermenéutica en la que se interpretaron los datos obtenidos y se analizaron bajo los criterios propios de la investigación. Los resultados obtenidos reflejan adecuadas estrategias didácticas planteadas, entre ellas se encuentran aula inclusiva, educación a distancia, aula digital, aprendizaje cooperativo, estimulación con arte, sonidos y movimientos, lectura comprensiva, estimulación con deporte y aprendizaje cooperativo en donde se incluyen los padres de familia para participar en su desarrollo de habilidades y nuevos conocimientos, por ello algunas publicaciones indican que estas estrategias utilizadas han sido muy factibles para los docentes y les permitió cumplir con las metas propuestas.
基于建构主义的概率论与数理统计课程融入数学建模思想方法的研究与实践
Authors:   陆军装甲兵学院, 杜 健 , 许 传青 ,   北京建筑大学, 胡 红娟 ,   陆军装甲兵学院, 李 慧珍 ,   陆军装甲兵学院
Published: December 2022

概率论与数理统计是大学的基础实践课程，对培养学生创新应用能力具有重要意义。本文以建构主义的教育理念为指导，在分析传统概率论与数理统计课程教学现状的基础上，从全方位渗透数学建模思想方法、构建具有交叉学科知识的内容体系、开发设计具有现实背景的建模案例、形成具有探究启发式的教学模式等四个方面，提出了融入数学建模思想方法的基本策略。此外，本文在教学实践案例，对建构学生的知识体系、培养解决问题的应用能力方面给出了指导性措施。
Maternal Blood Trace Element Levels in Preeclampsia: Comprehensive Systematic Review and Meta-Analysis
Authors: Hapsari Wening , Putra Achmad Januar Er
Published: December 2022

Introduction: Deficit in trace elements was frequent in pregnant women and could lead to preeclampsia development. This meta-analysis aimed to determine calcium, magnesium, zinc, iron, and copper serum levels in preeclampsia women compared to healthy pregnant women.
Methods: A systematic search is conducted in PubMed, ScienceDirect, and Google Scholar from inception into March 25th, 2022 using keywords of “("calcium" OR "magnesium" OR "zinc" OR "copper" OR "iron" OR "trace element" OR "trace elements") AND ("serum" OR "blood") AND ("preeclampsia")”. Articles obtained from PubMed, ScienceDirect, and Google Scholar were 62, 31, and 119 respectively.  The article screening process was based on the PRISMA 2020 guidelines. Study quality was assessed using NOS.
Results: Fifty-four studies were included in this systematic review. Pooled analysis revealed that serum calcium (SMD = (-1.66; 95% CI = -2.05 to -1.28, magnesium (SMD = -1.28; 95% CI = -1.37 to -1.20, and zinc were significantly lower in preeclampsia (SMD = -2.4; 95% CI = -4.11 to -0.7. Serum iron was higher in preeclampsia (SMD = 1.71; 95% CI = 0.21 to 3.21). No significant different difference in serum copper level.
Conclusion: The mean blood levels of calcium, magnesium, and zinc were considerably lower, while blood iron levels were higher in preeclamptic women compared to the healthy pregnant group. Copper levels were not significantly different between the two groups.
Pituitary Stem Interruption Syndrome (SITP) diagnosed in childhood in a case at the Center Hospitalier Universitaire de Libreville (CHUL)
Authors:   Centre Hospitalier Universitaire de Libreville, Gabon., NGAILA Nesta Patricia ZIZA
Published: December 2022

Interrupted pituitary stalk syndrome (PITS) is a hypothalamic-pituitary morphological abnormality characterized by a slender or absent pituitary stalk, anterior pituitary hypoplasia, and ectopic posterior pituitary. Hormonal assessment and imaging are crucial for the diagnosis, early management can improve the child's stature prognosis. We report the case of an 8-year-old child seen in endocrinology consultation for growth retardation. His medical history revealed acute fetal distress at birth, neonatal jaundice, and numerous consultations in early childhood for this anomaly. The clinical examination found a statural delay of -3DS, bilateral cryptorchidism, with small testicles. The hormonal balance found multiple pituitary deficits and Magnetic Resonance Imaging showed an absence of the pituitary stalk, anterior pituitary hypoplasia, and ectopia of the posterior pituitary. Deficient hormone supplementation was instituted. This case relates the typical picture of hypopituitarism by the absence of the pituitary stalk in a context where the disease is probably underdiagnosed due to lack of technical support in sub-Saharan Africa and little known. This explains the diagnostic error in our case, moreover, it allows us to pay particular attention to the meticulous monitoring of the growth of children who have presented perinatal anomalies, and the multidisciplinary exploration in the event of growth disorders.
Men’s Experiences of Gender Based Violence in Selected Compounds of Lusaka Urban
Authors:   University of Zambia, School of Education., Kalimaposo Kalisto , Mukando Maybin ,   University of Zambia, School of Education., Milupi Inonge ,   University of Zambia, School of Education., Mubita Kaiko ,   University of Zambia, School of Education., Hambulo Farrelli ,   University of Zambia, School of Education.
Published: December 2022

The study investigated men’s experiences of Gender Based Violence in selected compounds of Lusaka Urban. The study adopted an interpretivist perspective which seeks to understand participants’ lived experiences of Gender based Violence. The study was conducted in two compounds of Lusaka Urban. The study sites were chosen because of their high prevalence of Gender Based Violence as reported on social media. The study was premised on the following research objectives; to determine the nature of Gender Based Violence against men, to explore the factors that lead to Gender Based Violence against men and to investigate men’s reactions in the face of Gender Based Violence. The study sample consisted of fourty-six (46) participants, thirty four (34) of whom were men from both Garden and Matero Compounds, four (4) representatives from the Zambia Police Victim Support Unit and eight (8) Church leaders. Purposive and convenient sampling techniques were used. The findings of the study revealed that among the forms of Gender Based Violence perpetrated against men were emotional abuse, sexual abuse, physical assault, financial abuse and verbal abuse. Other factors that led to Gender Based Violence against men were failure of a man to provide for family needs especially after change of economic status, alcohol abuse, retaliation to past mistreatment of wives by husbands, adultery and psychological disorders. Regarding men’s reactions in the face of Gender Based Violence, the study showed that few men reported cases of Gender Based Violence against them. This was attributed to the fact that men faced barriers such as societal view of battered men, police attitudes towards battered men and being ignored by the law enforcement bodies.
Introducing Al-Farabi’s Political Philosophy to the Modern Politics
Authors: Azzuhri Anggi
Published: December 2022

Al-Farabi categorized cities, the smallest scale of a political association, into four types: the virtuous city, the ignorant city, the wicked city, the diverted city, and the erring city. Al-Farabi terminology indicates that morality is the red-line that differs the nature of each city, although there is no straightforward statement in his treaties. Despite many admirations by later philosophers on Al-Farabi’s political philosophy, his concept is still considered a utopia. Also, it seems that no historical account mentioned any (Islamic) empire, applying Al-Farabi’s ideas on politics. Even Ibn Khaldun criticized Al-Farabi’s concept based on the pragmatic perspective of civilization. However, this fact does not imply the irrelevancy of Al-Farabi’s politics in the practical realm. The question is only regarding what extent Al-Farabi ideas work with politics, particularly modern politics? This study aims to correlate Al-Farabi ideal concept and modern politics. The methodology of this research is qualitative conceptual analysis since the two variables are in the theoretical realm. It can be concluded that Politics in Al-Farabi’s notion strongly connected with Ethics and Morality rather than Authority. An ideal state can actualize through the collective consciousness of true felicity, by which the type of cities is divided. Although Al-Farabi’s political philosophy is quite unapplicable, particularly in the modern age, its role as the highest political principles is undeniable. The essential aspect of Al-Farabi’s political employment in the modern era is his fundamental idea, i.e., ethical society. Establishing an ethical state is more critical than Al-Farabi’s political application entirely.
Does Ellipsis Really Exist in the Qurʾān?
Authors: Alamiri Zaid
Published: December 2022

Departing from Systemic Functional Linguistics, this study, which represents preliminary findings, asserts that ellipsis in the Qurʾān, as a grammatical cohesive device, does not tend to occur more frequently. Arabic linguistics, for its part, has approached ellipsis and continues from exclusive intra-sentence relations governed by syntactic rules. Understood as such, ellipsis doesn’t contribute to the cohesiveness of text― a notion absent in the Arabic linguistic tradition.  To compensate for the ellipsis’s contribution to text, the Qurʾān employs two other strategies; the cohesive relationship of Reference, and stylistic techniques.   The study shows that SFL-based ellipsis analysis is more productive and useful for understanding the mechanisms of text building elements than the syntactic approach.  However, more research is required to get a more thorough knowledge of ellipsis in the Qurʾān, which will eventually contribute to the ellipsis theory in the Arabic language.
Al-Muḥaqqiq al-Iṣfahānī’s Ontological Argument and Spinoza’s Ontological Arguments for the Existence of God
Authors: Khayatzadeh Mehdi , Pakdin Asl Mohammad
Published: December 2022

Al-Muḥaqqiq al-Iṣfahānī (1878-1942) and Spinoza (1632-1677), two prominent intellectuals of the Islamic and Western worlds respectively, have proposed different versions of the ontological argument for the existence of God. I present five versions of al-Muḥaqqiq al-Iṣfahānī’s argument in three general dimensions: first, the concept of the necessary being (wājib al-wujūd) as a mental concept; second, the concept of the necessary being as a representation of something external; and finally, the reality of the necessary being or what externally exists by its essence. Only one of these versions is compatible with al-Muḥaqqiq al-Iṣfahānī’s words. On the other hand, Spinoza has presented six arguments in which he has deployed the concept of God in three ways: the concept of God as a concept, the concept of God as a representation of something external, and the mental existence of this concept. In this paper, I compare the accurate construal of al-Muḥaqqiq al-Iṣfahānī’s argument with Spinoza’s six arguments, whereby I make a case for a strong similarity between the grounds and forms of the ontological argument as formulated by these two intellectuals.
O PAPEL DE MULHERES ESCRAVAS NEGRAS NA SOCIEDADE AFRICANA E NA SOCIEDADE BRASILEIRA NO PERÍODO DE ESCRAVIDÃO: SÉCULO XVI E XIX
Authors: Cavalcanti Genivaldo Bezerra
Published: December 2022

Este estudo tem o objetivo de conhecer a trajetória de Mulheres africanas no período colonial brasileiro, a captura de escravas negras e sua vinda para as terras do Brasil marcou um violento fenômeno praticado com finalidade de escravização no tráfico de pessoas para a mão de obra do comércio da época. O artigo não se aprofunda nas peculiaridades das tribos africanas em relação as suas culturas tendo o foco central na mulher negra e sua escravização no Brasil no século XVI E XIX.
L'interférence de la gémination dans la prononciation des étudiants arabophones apprenant le français [The interference of gemination in the pronunciation of Arabic-speaking students learning French]
Authors: Nawafleh Ahmad
Published: December 2022

Cette étude expérimentale se propose de diagnostiquer l’effet de la langue arabe sur la prononciation des étu-diants arabophones apprenant le français. Elle comporte les résultats de mesures acoustiques portant sur la durée acoustique des consonnes graphiquement doubles dans la prononciation de locutrices natives du fran-çais et d’étudiantes jordaniennes. L’étude inclut également des tests perceptifs effectués auprès d’auditeurs arabophones non apprenants. L’étude acoustique démontrent que les consonnes cibles prononcées par les apprenantes sont significativement plus longues que celles produites par les locutrices françaises. Les tests de perception soulignent que la plupart des mots cibles ont été réalisés avec des consonnes géminées par les ap-prenantes. Les apprenantes prononcent les consonnes, qui doivent habituellement se prononcer comme si elles étaient simples, de manière géminée. La recherche trouve sa conclusion dans des propositions pratiques ayant pour objet d’aider les apprenants à surmonter l’interférence de la gémination de l’arabe vers le français.
Learner autonomy: Exploring teachers’ perceptions and classroom practices
Authors: Chinpakdee Muthita
Published: December 2022

This article reports on research conducted in Thailand to explore experienced EFL secondary school teachers’ understandings of learner autonomy (LA) and their classroom practice to promote autonomous language learning. Qualitative analysis of teacher interviews and class observation reveals that although the teachers showed good understandings of LA principles and supported LA development, they had difficulties putting their ideas into practice. This article examines the convergence and divergence between the teachers’ stated perceptions and their classroom practices. It also uncovers factors that can mediate teachers’ approaches to fostering LA. Future research directions and practical implications of the research are also discussed. 1 Introduction Learner autonomy (LA) is a concept that has garnered empirical and practical interest, particularly from researchers in the field of foreign language learning and teaching since the 1970’s (Palfreyman & Benson, 2018). Much effort has been put to promote LA development among language learners. Initially, LA was strongly associated with self-access learning, a mode of learning in which learners can decide for themselves what, when, where and how to learn. However, it was found that providing learners with self-access learning resources is not adequate to foster LA. In the 1980’s researchers started to conceptualize LA as learners’ capacity to take charge of their learning which can be developed through strategy instruction and metacognitive training (Benson, 2011). This shift in view emphasizes the important role of the teachers in helping their learners develop essential knowledge and strategic skills to learn autonomously. While there are many studies that look at LA development from learners’ perspectives, little research has empirically investigated how LA is operationalized and put to practice in classrooms by teachers. This study seeks to fill this research gap by exploring language teachers’ perceptions about LA, the extent to which they put their theoretical knowledge into action, and factors that may support or limit their innovative attempts to develop LA. Share
Speaking issues faced by Indonesian students during classroom discussions in the US
Authors: Kusuma I Putu Indra
Published: December 2022

Without sufficient English-speaking skills, international students, including those from Indonesia, will face fundamental issues in their studies, especially in classroom discussions. A descriptive study was conducted to describe the issues faced by Indonesian students during classroom discussions in a mid-western US university. These issues were viewed from the perspective of internal factors such as linguistic knowledge, motivation, anxiety, and topic knowledge. Specifically, this study employed a convergent mixed-methods design. The 20 international students participating in this study were majoring in different disciplines and were selected using a purposive sampling technique. This study collected data using online questionnaires, consisting of 23 close-ended items, followed by semi-structured interviews with five willing participants. The quantitative data (online questionnaires) were put through a descriptive statistics analysis, while the qualitative data (semi-structured interviews) were studied using the content analysis technique. The findings showed that, in general, these Indonesian students had issues regarding correct grammar use and proper vocabulary choice during classroom discussions. They also experienced anxiety when participating in classroom discussions. Nevertheless, they did not have such issues in pronunciation, motivation, and topic knowledge. Based on the results mentioned above, possible implications for ESL/EFL are also discussed in this study.
Analisis stratigrafi dan sejarah pengendapan Daerah Cibenda, Kabupaten Ciamis, Jawa Barat dan sekitarnya
Authors: Adam Muhammad Daffa Kevin , Rochmana Yogie Zulkurnia
Published: December 2022

Analisis stratigrafi dan sejarah pengendapan pada daerah Cibenda, Kabupaten Ciamis, Jawa Barat, bertujuan mengidentifikasi kondisi geologi pada daerah penelitian dari aspek stratigrafi. Hasil pengamatan lapangan yang didapatkan dengan metode observasi lapangan kemudian direkonstruksi menjadi sebuah model sejarah geologi dengan menggunakan analisis laboratorium dan analisis studio. Pada lokasi penelitian diketahui stratigrafi daerah penelitian dari tua ke muda mencakup Formasi Jampang (Tomj), Formasi Kalipucang (Tmkl), Formasi Halang (Tmph) dan Formasi Tapak (Tpt). Secara tektonik, daerah penelitian terdapat pada jalur Pegunungan Selatan. Pengetahuan mengenai stratigrafi suatu daerah dapat menjadi informasi bagi penelitian lebih lanjut maupun diaplikasikan terhadap pengembangan wilayah. Oleh karena itu, peneliti memilih topik ini untuk diteliti.
Analisis perubahan morfometri dan meander Sungai Way Tebu, Kabupaten Tanggamus, Provinsi Lampung
Authors: Rini Feqqi Indah , Sutriyono Edy
Published: December 2022

Sungai Way Tebu merupakan salah satu sungai yang berada pada Kabupaten Tanggamus, Provinsi Lampung. Secara geologi termasuk ke dalam lembar geologi Kotaagung yang memiliki beberapa fornasi antara lain: Komplek Gunung Kasih (Pzg), Formasi Menanga (Km), Formasi Hulusimpang (Tomh), Formasi Gading (Tomg), dan Formasi Qhv. Sungai Way Tebu didominasi oleh pola berkelok atau meander yang disebabkan oleh proses pengikisan dan pengendapan pada sungai. Penelitian ini bertujuan untuk menganalisis perubahan morfometri meander sungai Way Tebu pada tahun 1996 dan tahun 2021. Analisis morfometri dilakukan menggunakan data spasial. Data yang digunakan yaitu citra landsat 5 TM dengan menggabungkan band 7, band 4, dan band 2 untuk menganalisis sungai tahun 1996 dan citra landsat 8 OLI/TIRS dengan menggabungkan band 7, band 5, dan band 3 unruk menganalisis sungai tahun 2021. Hasil perhitungan parameter morfometri, dapat diketahui bahwa sungai mengalami perubahan nilai parameter dari tahun 1996 ke tahun 2021. Berdasarkan hasil perhitungan setiap parameter, nilai parameter pada tahun 1996 mengalami peningkatan pada tahun 2021. Sungai Way Tebu tahun 1996 menunjukan nilai rata-rata sinousitas 1,72 dan mengalami kenaikan pada tahun 2021 menjadi 1,85, nilai sinousitas tersebut memiliki nilai >1,5 yang berarti Sungai Way Tebu memiliki bentuk berkelok yang menandakan bahwa sungai tersebut termasuk ke dalam sungai stadia dewasa. Peningkatan nilai sinousitas sungai menunjukkan bahwa proses dinamika pembentukan alur sungai masih berlangsung hingga saat ini. Model perubahan meander tersebut menunjukkan bahwa perubahan pada bentuk   lingkar meander dipengaruhi oleh faktor geologi di sekitarnya, keberadaan endapan material sedimen membuat arah dari aliran sungai berubah dan mengerosi bagian badan sungai yang dituju oleh aliran sungai.
Karakteristik morfometri dan morfodinamika Sub Daerah Aliran Sungai Batang Sukam, Kabupaten Sijunjung, Sumatera Barat
Authors: Nasution Ishmi Khafishah , Sutriyono Edy
Published: December 2022

Sungai Batang Sukam berada di kecamatan Lubuk Tarok, Kabupaten Sijunjung, Sumatera Barat berada pada bentuk lahan dataran rendah yang dikontrol oleh Formasi Sawahtambang (Tost) dan Formasi Ombilin (Tmo) dengan litologi batuan sedimen. Pola pengaliran sungai meandering ini memiliki daerah limpah banjir yang dipengaruhi oleh kondisi geologi berupa proses erosi dan pengendapan sebagai pengaruh internal serta perubahan iklim sebagai pengaruh eksternal dalam sistem. Penelitian ini bertujuan untuk menentukan morfodinamika dan karakteristik meandering sebagai hasil sedimentasi pada daerah limpah banjir dengan membandingkan dan menghubungkan perubahan morfometri aliran sungai, morfologi sungai dan perubahan meander sungai tahun 1996 dengan data citra Landsat 5 TM pada tanggal 12 Juli 1996 dan 2021 dengan data citra Landsat 8 OLI/TIRS pada tanggal 30 November 2021 menggunakan software ArcMap,  Perubahan morfometri sungai ditunjukkan dengan kenaikan dan penurunan pada rata-rata nilai parameter, perhitungan tersebut juga menunjukkan bahwa daerah penelitian termasuk kedalam meander. Berdasarkan nilai yang didapatkan pada tahun 1996 dengan 2021 nilai panjang lebar liku (L) turun dari nilai 572,54 m ke 265,12 m, nilai  lebar sungai (W) turun dari nilai 72,47 m ke 67,87, nilai Panjang Sumbu (A) turun dari nilai 220,40 ke 216,80, nilai panjang aliran sungai (S) turun dari 766,40 ke 760,80, nilai jari-jari kelengkungan (R) turun dari 111,00 ke 102,27. Sedangkan  nilai sinousitas (C) sungai meningkat dari 1,67 ke 1,78 Sedangkan morfodinamika sungai dipengaruhi oleh kondisi geologi tingginya tingkat proses pengendapan dibandingkan dengan proses erosi (Ae/Ad<1). Perubahan morfometri meander menunjukkan tipe perubahan yang didominasi oleh tipe simple. Morfologi sungai termasuk kedalam tipe bentuk sungai Irregular – Wandering dengan garis tingkat material sedimen yang cukup melimpah sebesar 50 %, daerah aliran sungai Batang Sukam termasuk kedalam kelas stadia dewasa
Karakteristik batuan ultramafik Daerah Tamainusi, Kecamatan Soyo Jaya, Kabupaten Morowali Utara, Provinsi Sulawesi Tengah
Authors: Asdar Muhammad Firman , Okto Ali , Ngkoimani Laode
Published: December 2022

Daerah penelitian terletak di wilayah IUP PT.Cipta Hutama Maranti Kecamatan Soyo Jaya, Kabupaten Morowali Utara, Provinsi Sulawesi Tengah. Batuan Ultramafik terhampar luas di bagian Timur dan Tenggara Sulawesi sehingga menarik untuk diadakannya penelitian agar bisa mengetaui informasi geologi dari batuan ultramafik itu sendiri.Tujuan dari penelitian ini untuk mengetahui karakteristik batuan ultramafik berdasarkan analisis petrografi dan geokimia. Hasil analisis petrografi menunjukkan batuan di daerah ini termasuk jenis batuan ultramafik yang terdiri dari dunit, hazburgit dan klinopiroksenit. Mineral utamanya didominasi olivin dan piroksen serta mineral sekunder yang tersusun atas serpentin, magnetit dan garnet. Analisis geokimia batuan ultramafik pada daerah ini termasuk dalam kelompok peridotit gabro berdasarkan perbandingan unsur total alkali (Na2O+K2O) dan silika (SiO2) terbentuk pada tatanan tektonik mid oceanic ridge dengan seri magma thoelitik yang dicirkan tinggi kandungan unsur MgO dan FeO serta rendah kandungan Al2O3.
Inventarisasi keragaman geologi pada Daerah Wisata Air Terjun Moramo dan Sekitarnya, Kabupaten Konawe Selatan, Sulawesi Tenggara
Authors: Darnawati Darnawati , Masri Masri , Bahdad Bahdad , Hasria Hasria
Published: December 2022

Telah dilakukan inventarisasi keragaman geologi pada daerah wisata air terjun Moramo dan sekitarnya. Kegiatan inventarisasi berfokus pada tiga Kawasan: air terjun, pantai, dan daerah penambangan batugamping. Keragaman geologi yang diinventarisasi mencakup keragaman litologi dan bentang alam (geomorphosite), serta proses kartisifikasi dan morfodinamika pantai. Satuan geomorfologi daerah penelitian berupa satuan perbukitan tersayat tajam dan satuan perbukitan bergelombang. Variasi litologi batugamping kristalin dan marmer yang disetarakan dengan batuan penyusun Formasi Laonti. Daerah penelitian dibagi menjadi tiga situs geologi (geosite). Geosite Sumber Sari dicirikan oleh air terjun dan produk karst berupa travertin, stalaktit, dan pilar pada gua karbonat. Geosite Sanggula berupa area tambang rakyat yang dicirikan oleh tebing marmer oleh aktivitas penambangan dan variasi derajat pelapukan. Geosite Wawatu berupa pantai dengan kenampakan erosi lateral yang membentuk ornamen coastal karren, tebing berdinding sedang pada garis pantai.
THE ROLE OF DETERMINANT GENES OF STEROID HORMONES DYSFUNCTION REGULATORS (CYP17A1-RS743572, CYP19A1-RS247015) IN THE DEVELOPMENT OF PCOS IN WOMEN WITH INFERTILITY
Authors: Ikhtiyarova Gulchekhra , Музаффарова М.Х.
Published: December 2022

Summary. Purpose: to develop prognostic criteria for the outcomes of ART programs in women with infertility in PCOS based on molecular genetic predictors of folliculogenesis disorders. Material and research methods. To solve the tasks set in the work, 125 women were examined: group first - 45 women with primary PCOS and infertility; group second - 46 women with infertility and PCOS in preparation for ART; group third 26 conditionally healthy women. Based on the foregoing, we presented the data of our own studies on the assessment of the state, the genes of steroid hormones (CYP17A1-rs743572, CYP19A1-rs247015) based on the analysis of laboratory data.

Results and its discussion. Regarding the influence of the polymorphism of the CY19A1 rs2470152 gene on the development of PCOS, mutant alleles were found to be significantly higher in patients than in the control group. When we divided the main group into MC(+) and MC(-) in terms of CYP19A1 and compared with the control group, we found that the homozygous mutant genotype was found to be greater in the MC(+) and MC(-) group compared to the control group. With this, we can conclude that the homozygous mutational form of the CYP19A1 gene plays a convincing inducible role in PCOS and our result was significant (chi2 - 5.74; p<0.02 in the main group; chi2=5.2; p=0.02 in patients with metabolic syndrome and chi2=3.9; p<0.05 in patients without metabolic syndrome). However, the study did not reveal an induced effect on the heterozygous genotype in the development of PCOS (chi2<3.85; p>0.05). At the same time, the wild-type homozygous variant played a protective role in terms of the appearance of PCOS in the main group, as well as in the MC (+) and MC (-) groups (OR≥0.5). When it comes to the Hardy Weinberg equation, we found no significant difference between the expected and observed results in the main group. Estimates of polymorphism prediction efficiency, as already mentioned, showed only 0.6, which means that the prediction efficiency was not reliable in terms of mutant allele and genotype.

In conclusion, from the study of CY17A1 polymorphism in patients with PCOS, it can be said that the GG mutant genotype was statistically significantly more common in patients compared to the control group. When dividing PCOS patients, they were divided into groups and compared with the control group, MS+ PCOS patients had a lower level of the mutant form (GG) genotype compared to the control group, but in MS-PCOS patients compared to the control group, the mutant gene was determined more.
ОЦЕНКА ПАРАМЕТРОВ ИММУННОЙ СИСТЕМЫ У ДЕТЕЙ C ГАСТРОДУОДЕНАЛЬНОЙ ПАТОЛОГИЕЙ
Authors: Шодиева Мушарраф
Published: December 2022

Актуальность: У Детей иммунитет к инфекции Х пилори на ранней стадии может служить своего рода моделью патологической реакции и обучения. В условиях Республики Узбекистан такие исследования не проводились, однако увеличение веса, тенденция к омоложению и высокая частота осложнений диктуют необходимость изучения данного вопроса. Пациенты и методы. Цель работы из всей когорты обследованных детей в исследование были включены дети с гастродуоденальной патологией, связанной и не связанной с ХП. Материалы и методы исследования: Согласно поставленным задачам работы, из всей когорты обследованных детей в исследование были включены дети с НР ассоциированной и не ассоциированной гастродуоденальной патологией. Нами проведено изучение медиаторов иммунного ответа на примере IL-1β и TNFα у 165 больных детей и для сравнения у 50 практически здоровых детей аналогичного возраста, составивших контрольную группу. Исходя из выше сказанного, группы детей с H.pilori «+» и H.pilori «-» патологии гастродуоденальной зоны были подразделены на 2 подгруппы в зависимости от возраста.  Результаты: уровни IL-1B в контрольной группе детей 7-14 лет составили 21,6±0,86 пг/мл по сравнению с 24,2±0,72 пг/мл у детей 15-18 лет. У детей 15-18 лет 27,4±0,76 пг/мл.
ОСОБЕННОСТИ РАННЕЙ НЕОНАТАЛЬНОЙ АДАПТАЦИИ НЕДОНОШЕННЫХ ДЕТЕЙ ИЗВЛЕЧЕННЫХ ОПЕРАТИВНЫМ ПУТЕМ ОТ МАТЕРЕЙ С ПРЕЭКЛАМПСИЕЙ ТЯЖЕЛОЙ СТЕПЕНИ
Authors: Юлдашева Гулноз
Published: December 2022

В обзоре приведены особенности клинического  течения ранней неонатальной адаптации недоношенных детей в зависимости от метода родоразрешения беременных с тяжелой преэклампсией.  Установлено более благоприятное течение неонатальной адаптации недоношенных детей от матерей с преэклампсией извлеченных путем кесарево сечения. Доказано снижение частоты встречаемости СДР синдрома, заболеваемости и  летальности у недоношенных детей извлеченных оперативным путём при преэклампсии.
СИНДРОМ ВИСКОТТА-ОЛДРИЧА. КРАТКОЕ ОПИСАНИЕ БОЛЕЗНИ
Authors: Ханова Хилолахон , Исмаилова Адолат
Published: December 2022

Цель исследования: описание клинического случая больного с Синдромом Вискотта-Олдрича

Материалы и методы: нами представлен клинический случай мальчика 2007 года рождения с клинической картиной первичного иммунодефицита, проявляющийся в виде Синдрома Вискотта-Олдрича. Ребенок находится под наблюдением врача-гематолога и врача-иммунолога в Центре Детской гематологии, онкологии и клиинической иммунологии.

Результаты и обсуждение: У ребенка наблюдался большой спектр клинических и лабораторных симптомов, таких как тяжелое состояние ребенка, выраженная интоксикация, гепатоспленомегалия, петехиальные высыпания на коже тела, геморрагический синдром, в крови анемия неясного генеза, лейкоцитоз, ускорение СОЭ, тромбоцитопения. Учитывая все вышеизложенные показатели и данные был выставлен диагноз: Первичный Иммунодефицит , Синдром Вискотта-Олдрича.

Выводы: основываясь на данный клинический случай можно убедиться, что клиническая картина, в том числе и характерная ему триада симптомов данного заболевания достаточно специфична, что помогает врачам при дифференциальной диагностике с другими заболеваниями.
ИММУННЫЙ СТАТУС И КЛИНИКО-ДИАГНОСТИЧЕСКИЕ ОСОБЕННОСТИ ТЕЧЕНИЯ ХРОНИЧЕСКОГО БРОНХИТА У ДЕТЕЙ
Authors: Каримова Нилуфар
Published: December 2022

Целью исследования было изучить клинико-биохимические и иммунологические особенности хронического бронхита у детей. Под нашим наблюдением находилось 40 детей с хроническим бронхитом в возрасте от 3 до 15 лет. Полученные нами результаты показывают, что при хроническом бронхите клинико-функциональные исследования имеют существенное значение в своевременной диагностике заболевания. При хроническом бронхите наблюдается значительная активность процессов ПОЛ-АОС в мембране лимфоцитов, выражающаяся повышением уровня МДА и ДК, которые были выше в группе больных 7-15 лет. Исследование иммунного статуса позволило выявить глубокие изменения Т-клеточного звена иммунитета в виде значительного снижения количества и функциональной активности нейтрофилов.
Perioperative fluid management in children: an updated review
Authors: Beels M , Stevens S , Saldien V
Published: December 2022

Background: Perioperative fluid management in children has been a major topic for debate.

Objectives: Our aim is to review the current evidence on perioperative fluid management in children including: type of fluid, administration rates, preoperative fluid intake and monitoring techniques.

Design: Narrative review.

Method: Following the PRISMA-S guidelines we performed a search (2010-March 2022) in databases Medline (through PubMed) and Cochrane Library. 4297 citations were found and screened by two independent researchers. After screening, 64 articles were withheld for our review.

Results: The perioperative administration of isotonic fluids is safer than hypotonic solutions, concerning the development of hyponatremia. A balanced isotonic solution with 1-2,5% glucose should be used as perioperative maintenance IV fluid in children (1 month to 18 years). Colloids can be used in children when inadequate effect in volume correction is achieved with crystalloids. The preferred synthetic colloid for children is a third generation HES in a balanced solution. To date, most clinicians use the “4-2-1 rule” for calculating fluid rate. This may not be the optimal fluid rate, as little research has been done. Preoperative fasting for clear fluids should be limited to 1 hour, children should even be encouraged to drink up until 1 hour before induction. Respiratory variation of aortic blood flow peak velocity (ΔVpeak) with echocardiography is currently the most reliable technique for evaluating fluid responsiveness in children.
The use of cognitive aids in the operating room: a systematic review
Authors: Claeys A , Van Den Eynde R , Rex S
Published: December 2022

Background: Cognitive aids (CAs) are clinical tools guiding clinical decision-making during critical events in the operating room. They may counteract the adverse effects of stress on the non-technical skills of the attending clinician(s). Although most clinicians acknowledge the importance of CAs, their uptake in clinical practice seems to be lagging behind. This situation has led us to investigate which features of CAs may enhance their uptake. Therefore, in this systematic review we explored the optimums regarding the 1) timing to consult the CA, 2) person consulting the CA, 3) location of the CA in the operating room, 4) CA design (paper vs. electronic), 5) CA lay-out, 6) reader of the CA and 7) if the use of CAs in the form of decision support tools lead to improved outcome.

Methods: Seven PICO-questions guided our literature search in 4 biomedical databases (MEDLINE, Embase, Web of Science and Google Scholar). We selected English-language randomized controlled trials (RCTs), observational studies and expert opinions discussing the use of cognitive aids during life-threatening events in the operating theatre. Articles discussing non-urgent or non-operating room settings were excluded. The quality of evidence was evaluated with the Grading of Recommendations Assessment, Development and Evaluation (GRADE).

Results: We found 7 RCTs, 14 observational studies and 6 expert opinions. All trials were conducted in a simulation environment. The person who should trigger the use of a cognitive aid and the optimal timing of its initiation, could not be defined by the current literature. The ideal location of the cognitive aids remains also unclear.

A favorable lay-out of an aid should be well-structured, standardized and easily readable. In addition, several potentially beneficial design features are described.
RCT’s could not demonstrate a possible superiority of either electronic or paper-based aids. Both have their advantages and disadvantages. Furthermore, electronic decision support tools are potentially associated with an enhanced performance of the clinician. Likewise, the presence of a reader was associated with an improved performance of key steps in the management of a critical event. However, it remains unclear who should fulfill this role.

Conclusion: Several features of the design or utilization of CAs may play a role in enhancing the uptake of CAs in clinical practice during the management of a critical event in the operating room. However, robust evidence supporting the use of a certain feature over another is lacking.
Historical vignette – The Mapleson G, an original pediatric anesthesia circuit
Authors: Gribomont B.F. , Le Polain de Waroux B , Veyckemans F.A. , Ki B.K. , Kabre Y.B. , Neighbour R.C. , Baele P.l.
Published: December 2022

A previously unpublished pediatric anesthesia circuit is presented here. It was invented and constructed by Dr Bernard-François Gribomont (hence called BFG circuit) around 1965 as a response to the important pediatric case load in the university hospital of Lovanium, near Leopoldville (now Kinshasa, DRC). The original objective was to find a simple solution that would enable the manual ventilation (assisted or controlled) of young children during ENT surgery, remaining very close to the child to reduce dead space while at the same time keeping far enough away from the surgeon in order to avoid obstructing their work.

It includes a short coaxial single piece circuit devoid of any mechanical valve connected to an in-line fresh gas ventilation bag; it does not fit into any existing Mapleson category. Hence, the authors propose to classify it in a new Mapleson G class. Its main advantages are conceptual simplicity, inherent safety, very low dead space accounting for minimal rebreathing and thus reduced fresh gas flow, small size and weight, and ease of use even during prolonged manual ventilation in small children. Its main drawback is difficult scavenging of expired gases. For logistical reasons it was abandoned in the nineties but could be of renewed interest in low-income countries.
THE SYSTEM OF ADDITIONAL ECOLOGICAL EDUCATION WITH USE OF IMMERSIVE TECHNOLOGIES AS A FACTOR OF SUSTAINABLE DEVELOPMENT
Authors:   Moscow State Regional University, Oparin R.V. , Arbuzova E.N. , Sumatokhin S.V. ,   F.M. Dostoevsky Omsk State University, Poleshchuk P.V. , Nazarov S.V.
Published: December 2022

The article scientifically describes the principles and stages of designing a system of additional environmental edu- cation using immersive learning technologies. The projected system is aimed at forming the individual activity of schoolchildren in solving environmental problems on the basis of social, scientific and aesthetic axiological systems that determine the content of environmental-biotechnical, environmental-research, environmental-aesthetic activi- ties. The main result of the implementation of this system is the ability of students to plan their activities to study independently, preserve and creatively transform the environment using traditional and immersive technologies. Immersive learning technologies are considered by the authors as a tool for the development of environmental and social responsibility of society. The results of an experimental test of the effectiveness of the culture-creative system of additional environmental education using traditional and immersive learning technologies are presented, which showed the high efficiency of the influence of innovative forms, means and methods of additional environmental education in the formation of environmental value orientations of schoolchildren.
FORMATION OF PROFESSIONAL VALUE ORIENTATIONS AMONG MEDICAL COLLEGE STUDENTS
Authors:   Moscow State Regional University, Balyan N.S.
Published: December 2022

The professional development of students is becoming an urgent problem in the system of secondary medical educa- tion. The article lists the methods that determine the formation of a professional value system in the educational process of medical college students.
THE METHOD OF EXPERIMENTAL DETERMINATION OF THE LEVEL OF FORMATION OF LOGIC UNIVERSAL ACTIONS IN TEACHING CHEMISTRY
Authors:   Moscow State Regional University, Zakabluk O.V. , Volkova S.A.
Published: December 2022

The article discusses the method of experimental determination of the level of formation of logical universal educational actions in teaching chemistry. Particular attention is paid to the peculiarities of selecting subjects for control and experimental groups. The dynamics of the level of formation of logical universal educational actions among students is demonstrated. Conclusions are drawn about the peculiarities of the formation of logical universal educa- tional actions, taking into account the age of students and the type of educational institution.
SAMPLE WORK PROGRAM IN CHEMISTRY: ONE STEP FORWARD, TWO STEPS BACK
Authors:   Moscow State Regional University, Zhurin A.A.
Published: December 2022

The article gives a critical analysis of the content and structure of the exemplary work program in chemistry for the basic school (grades 8–9). It is proved that the construction of a chemistry course on the basis of this program returns school chemical education to several decades ago.
METHODOLOGICAL TECHNIQUES FOR THE FORMATION OF MATHEMATICAL LITERACY IN TEACHING GEOGRAPHY
Authors:   Moscow State Regional University, Solodukhina N.N.
Published: December 2022

The article examines the relationship between geography and mathematics, clarifies the concept of «mathematical literacy» in teaching geography. Examples of geographical tasks with calculation tasks, control elements of the content of school geography, topics of mathematics sections necessary for completing tasks are given.
INTERACTIVE MUSEUM IN TEACHING NATURAL SCIENCES
Authors:   Moscow State Regional University, Popov A.G.
Published: December 2022

The study of the sciences of the natural cycle is connected with practice – without conducting experiments, demon- strative experiments and working with models, there will be no complete understanding of the subject. The aim of the study was to create an excursion program for the interactive gallery «Les» and conduct an educational route with schoolchildren and preschoolers. The method of teaching and enlightening the natural sciences of the population with the help of an interactive museum is considered. Experimental excursions were conducted with four groups of persons, which showed the pros and cons of using this method of teaching and education.
METHODOLOGICAL SUPPORT OF THE EDUCATIONAL PROGRAM AT THE UNIVERSITY
Authors:   Russian State Social University, Stepkina L.V. ,   Moscow University for the Humanities
Published: December 2022

The article presents the results of a study on the problem of methodological support for the implementation of educa- tional program at the university in the context of the transition of universities to a new level of professional training in connection with the transition to present-day federal state educational standards, taking into account professional standards. The author proposes a model of methodological support of the educational program and the main areas of activity. Based on the results of the work, the conclusion states the need for a systematic approach to the development of a model of methodological support of the educational process at the university and the need for further research of the problem of methodological support as a factor in improving the quality of training.
MEANS TO STIMULATE PROFESSIONAL ACTIVITY OF FUTURE TEACHER
Authors:   State Social and Humanitarian University, Kovaleva E.A.
Published: December 2022

The mechanism that provides the constant self-development and self-improvement of a teacher is an effective system of stimulating their activity. To stimulate professional development of teachers, an individual motivation should be identified and taken into account. The reward system based on flexible rewarding mechanisms can become a significant factor for the most teachers that influence the aspiration to activity developing professional competence.
ABOUT ETNOPEDAGOGICAL DIALOGUES IN THE SCIENTIFIC HERITAGE OF ACADEMICIAN OF THE RAE G.N. VOLKOV (FOR THE TEACHER’S ANNIVERSARY)
Authors:   Institute of Anthropology and Ethnology of the Russian Academy of Sciences, Tsallagova Z.B.
Published: December 2022

The scientific legacy of the outstanding teacher of our time, Academician of the Russian Academy of Education G.N. Volkov is extensive and multifaceted; a special place in it is occupied by the consideration of folk traditions of personality formation and various aspects of the traditional culture of education in the aspect of systematization of the basic concepts of ethnopedagogy in their correlation with the postulates of professional pedagogy, as well as as- pects of the ethnopedagogical dialogue of cultures of different peoples. Using a large amount of factual material, the scientist in his more than seven hundred publications (of which more than fifty monographs) convincingly proves the typological relationship, the similarity of the ethnopedagogical heritage of different peoples, which, in the current conditions of the education crisis, with a methodologically and methodologically competent approach, can become an essential part of the content base of the modern education.
THE ROLE OF LABORATORY ACTIVITIES IN THE PROCESS OF ENGINEERING PERSONNEL TRAINING
Authors: Dyatlova Е.P. , Voropanova M.A. , Novikov A.I.
Published: December 2022

The role of laboratory work in the system of training of engineering and technical specialists is considered. Ready- made stands of FESTO and SMC Pneumatic companies were used, supplemented with new equipment and a physi- cal model of a ventilation unit with an automated control system developed at the department. The importance of laboratory work for the assimilation and consolidation of the material passed, the acquisition of special knowledge and practical skills necessary in production activities is shown.
A HOMEROOM TEACHER – A SUBJECT OF ORGANIZATION OF EDUCATION OF STUDENTS OF THE EDUCATIONAL ORGANIZATION
Authors:   State Social and Humanitarian University, Mardakhaev L.V.
Published: December 2022

The article reveals the purpose of education in an educational organization; characterization of the basic document of education in an educational organization; the subject (class teacher) of the organization of educational activi- ties of students, his appointment; the essence and content of the activity of the class teacher; the characteristic of types of educational activity of the class teacher is given; the content of the initial stage of educational work with the class; the variants of the activity of the class teacher in uniting the class and educating its students are identified and characterized.
HUMANISTIC FUNDAMENTALS OF «THE PEDAGOGY OF UNDERSTANDING» IN THE PERIOD OF GLOBALIZATION
Authors:   Zhukov  Institute of the Troops of the National Guard of the Russian Federation, Fedoseeva I.A.
Published: December 2022

The article indicates the importance of «the pedagogy of understanding» as a science of the humanitarian field, ad- dressed to the personality of the student. An analysis of the concept of «the pedagogy of understanding» is presented. It is indicated that the transition to new electronic resources carries huge risks associated with isolation from the moral foundations of education, the value attitude to pedagogical activity, its purpose, content, and means. In con- clusion, it is concluded that a turn to the pedagogy of educative understanding is necessary, since education at all times acts as a strategic national priority that ensures the stability and prosperity of the state.
EDUCATIONAL ASPECTS OF SYSTEM AND SITUATIONAL APPROACHES TO COLLEGE MANAGEMENT IN MODERN CONDITIONS
Authors:   College of Kazan Innovative University named after V.G. Timiryasov, Khadiullina Y.V.
Published: December 2022

In the article the author expresses his ideas for ensuring the success of modern college management. Based on his own experience in managing a college at the Kazan Innovative University named after V.G. Timiryasov, the author reveals the advantage of combining systematic and situational management approaches, proves that such a symbio- sis is necessary when working with older teenagers who pass through a difficult period of their development during their college years. At the same time it is shown that if operational management is important in solving everyday problems, then a systematic approach is necessary in ensuring the strategic development of an institution in the system of vocational education.