bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalensi keberadaan gen pslA penyandi biofilm pada isolat klinis Pseudomonas aeruginosa di RSUP Prof. Dr. I G.N.G. Ngoerah periode Juli 2022 - Juni 2023
Authors: Jonathan Viriya , Darwinata Agus Eka , Pinatih Komang Januartha Putra , Tarini Ni Made Adi
Published: September 2024

Backgrounds: Pseudomonas aeruginosa can form a biofilm in less than 24 hours that is resistant to antibiotics. The pslA gene is exopolysaccharides involved in biofilm formation. Biofilm formed by pslA gene can increase opportunity for acquired resistance mechanisms to occur due to gene transfer between bacteria in the biofilm. This study purpose is to determine the prevalence of pslA gene in MDR and non-MDR P. aeruginosa clinical isolates at Prof. Dr. I.G.N.G. Ngoerah for period July 2022 - June 2023.
Methods: This research is qualitative descriptive study to determine the presence of pslA gene which detected using PCR method. Samples were taken using cross-sectional technique, available clinical isolates for period July 2022 - June 2023 at RSUP Prof. Dr. I.G.N.G. Ngoerah, with identification test VITEK-2 Compact and probability level ≥90%. Obtained data were analyzed descriptively by grouping based on research variables in the form of frequency distribution table.
Results: pslA gene is detected in 37 (88,09%) P. aeruginosa isolates, with 19 (90,47%) among them in MDR isolates, and 18 (85,71%) in non-MDR isolates.
Conclusion: pslA gene is found in MDR and Non-MDR P. aeruginosa isolates.
 
Latar Belakang: Pseudomonas aeruginosa membentuk biofilm kurang dari 24 jam yang resistan antibiotik. Gen pslA merupakan eksopolisakarida yang terlibat dalam pembentukan biofilm. Dengan adanya biofilm yang terbentuk oleh gen pslA dapat meningkatkan kesempatan terjadinya acquired resistance mechanisms akibat transfer gen antarbakteri dalam biofilm. Penelitian ini bertujuan mencari prevalensi gen pslA pada isolat klinis P. aeruginosa MDR dan non-MDR di RSUP Prof. Dr. I.G.N.G. Ngoerah Periode Juli 2022 - Juni 2023.
Metode: Penelitian adalah deskriptif kualitatif untuk mengetahui keberadaan gen pslA yang terdeteksi menggunakan metode PCR. Sampel penelitian diambil dengan teknik cross-sectional, yaitu isolat klinis yang tersedia selama periode Juli 2022 - Juni 2023 di Laboratorium Mikrobiologi RSUP Prof. Dr. I.G.N.G. Ngoerah, dengan tes identifikasi VITEK-2 Compact dan tingkat probabilitas identifikasi bakteri ≥90%. Data yang didapatkan dianalisis secara deskriptif dengan dikelompokkan berdasarkan variabel penelitian dalam bentuk tabel distribusi frekuensi.
Hasil: Terdeteksi gen pslA pada 37 (88,09%) isolat P. aeruginosa, dengan 19 (90,47%) diantaranya isolat MDR dan 18 (85,71%) pada isolat non-MDR.
Kesimpulan: Bakteri P. aeruginosa terdeteksi pada isolat klinis dari pasien di RSUP Prof. Dr. I.G.N.G. Ngoerah. Gen pslA ditemukan pada isolat P. aeruginosa MDR dan non-MDR.
Description of sociodemographics and dietary patterns in hypertension on Puskesmas II Denpasar Timur
Authors: Sudana Vidya Aditi , Sawitri Anak Agung Sagung , Pinatih Gde Ngurah Indraguna , Weta I Wayan
Published: September 2024

Introduction: Hypertension is a significant problem that is faced global-wide and nation-wide. The increasing number of hypertension cases is caused by numerous risk factors, both modifiable and non-modifiable. This research aims to know the description of diet as a risk factor of hypertension on primary healthcare facilities in Denpasar.
Method: This research is a descriptive, cross-sectional study done with consecutive sampling methods, researching on 93 respondents with 89 valid data and 4 invalid data. The research is done by filling a questionnaire, short interview, and blood pressure measurement.
Result: From the 89 valid data, it was found that the majority of respondents were female with the age group <30 years only male while the age group 30-39 years only female. The average frequency of respondents' meals per day was 3 times, the types of food consumed daily were liquids, staple foods, animal protein, plant protein, and vegetables. Fruits and junk food were consumed weekly and monthly while milk was only consumed monthly.
Conclusion: The daily nutrient consumption of hypertensive respondents in this study did not exceed the Indonesian RDA and DASH diet except magnesium. There is a need for a more comprehensive analytical study covering the correlation between diet and hypertension rate.
Description of Bronchial Wash (BW) as a diagnostic procedure for presumptive pulmonary tuberculosis with sputum scarce at Mataram Regional Hospital
Authors: Devirani Frizca , Priono Risky Irawan Putra , Sari Sri Kartika
Published: September 2024

Background: Some patients with presumptive TB cannot be bacteriologically confirmed because sputum is scarce. Improvement in the diagnostic value of using bronchoscopy for specimen collection has been reported. Due to its high sensitivity and specificity, PCR examination is recommended as an initial diagnostic test in all individuals suspected of pulmonary TB. This study aims to describe the results of the BW examination using the PCR GeneXpert MTB/RIF test in these populations treated at Mataram Regional General Hospital.
Methods: A descriptive study with secondary data collection from medical records at Mataram Regional General Hospital was conducted from July to December 2023. Statistical analysis was carried out using SPSS 26. Data on age, gender, examination results, and rifampicin sensitivity levels were described as proportions.
Results: A total of 143 patients were included in the analysis. Gender males (61.5%) and those aged 40-60 years (44.8%) were reported in this study. Of this examination, 89 (61.5%) patients reported positive, 52 (37.1%) negative, and 2 errors (1.4%). Based on the level of cycle threshold, it was reported that 16 patients (17.9%) were high, 12 patients (13.5%) were medium, 21 patients (23.6%) were low, and 40 patients (44.9%) were very low. No rifampicin resistance was reported in this study.
Conclusion: More than 50% of presumptive pulmonary TB patients with sputum scarce were reported positive through the BW and GeneXpert MTB/RIF examinations. This examination is recommended especially for these populations to get faster antituberculosis treatment.
Radiological images of retroperitoneal dedifferentiated liposarcoma: a rare case report
Authors: Junaedi Kadek Ogi , Martadiani Elysanti Dwi , Suadiatmika Dewa Gde Mahiswara
Published: September 2024

Background: Retroperitoneal liposarcoma is a rare tumor with an incidence of 2.5 per 1 million individuals. This tumor usually occurs at the age of 50-70 years, although incidents in children have been reported. Imaging techniques such as Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) play an important role in the diagnosis and follow-up of retroperitoneal liposarcoma. To date, only a few cases of differentiated retroperitoneal liposarcoma have been reported. Therefore, the author wants to explain cases of differentiated retroperitoneal liposarcoma, in this case accompanied by recurrence.
Case Report: A male 64-year-old patient complained of a lump appearing in his stomach. The lump in the stomach has appeared since the beginning of 2019. The first CT-Scan of the Abdomen without and with Contrast showed a left retroperitoneal mass with a cystic-solid-fat complex component, with internal septation, suspicious for microcalcification, which was attached to the nearby fascia and was pushing the left retroperitoneum organ to the right midline. The patient has undergone tumor resection, where in this patient the histopathological examination results showed a Malignant Mesenchymal Tumor, tending to Dedifferentiated Liposarcoma. A recurrence was reported after the surgery. The patient underwent another laparotomy surgery to resect the tumor. From the results of the last control, the patient's condition is still stable and from the results of abdominal MRI with the results there is no visible residive nor residual mass in the retroperitoneum or intraperitoneum.
Conclusion: Retroperitoneal liposarcoma is usually asymptomatic until the liposarcoma is large enough to press on the surrounding organs. It is often misdiagnosed due to its rarity and absence of symptoms. However, imaging techniques such as MRI and CT play an important role in the diagnosis and follow-up of retroperitoneal liposarcoma.
Fat transfer principles and applications in plastic surgery: a literature review
Authors: Suyata Astrinita Lestari , Sudarsa Shita Diwyani , Samsarga Gede Wara
Published: September 2024

Fat transfer of fat grafting is a renowned technique in plastic surgery, in which harvested fat tissue is injected beneath the skin into part of the body to be reconstructed. The fat transfer technique is the most popular choice for reconstructive and cosmetic procedures due to its low immunogenicity, low cost, and ease of access. In cosmetic, reconstructive plastic surgery, the fat transfer procedure is done by moving fat tissue from one body part to another body part. It consists of five main procedures: harvesting fat tissue, processing fat tissue, determining the recipient location, transferring or grafting fat tissue, and retaining or surviving the graft/fat transfer results. Procedures for fat transfer are typically done on the face, breasts, and buttocks. Fat transfer can lead to many consequences, such as skin issues, hematomas, infections, seromas, and even fatal fat emboli. This literature review aims to explain the principles of fat transfer and their applications in plastic surgery.
Risk factor of progression of diabetic retinopathy after cataract surgery: a systematic review and meta-analysis
Authors: Saraswati Putu Putri Titamia , Nyoman Yuni Suryani Dharmaputri P  , Suryathi Ni Made Ari , Andayani Ari
Published: September 2024

Background: Several researchers have looked into the connection between cataract surgery and the progression of diabetic retinopathy (DR) in various studies. However, the element that places a patient at risk for the advancement of diabetic retinopathy following cataract surgery is still unknown. The primary goal of this meta-analysis is to conduct a comprehensive review of the existing research discussing the factors connected to the progression of diabetic retinopathy after cataract surgery.
Methods: A literature search in scientific literature databases, including Pubmed, ScienceDirect, and Cochrane Library, was conducted. Review Manager 5.4 (Cochrane Collaboration, Oxford, UK) measured and analyzed the risk factor's role in the progression of DR after cataract surgery. A significance value below 0.05 was determined statistically significant. 
Results: This review included 657 people from eight different studies. It discovered a significant impact of various parameters on the evolution of diabetic retinopathy after cataract surgery. Serum HbA1c levels (with a mean difference of 1.16; p<0.00), diabetes duration (with a mean difference of 1.89; p=0.02), age at cataract surgery (with a mean difference of -1.72; p=0.01), and insulin treatment (with an odds ratio of 3.74; p<0.00) all demonstrated significant associations with diabetic retinopathy progression after cataract surgery.
Conclusion: Our meta-analysis found that blood HbA1c level, diabetes duration, age at cataract surgery, and insulin treatment were all significant risk variables for postoperative DR progression.
A 5-Year-Old Boy with Scurvy, Severe Anemia, and Severe Malnutrition: A Challenge
Authors: Putu Ianta Parama Siwi  , Putu Eka Pratiwi I Gusti Ayu , Lanang Sidiartha I Gusti
Published: September 2024

Background: Scurvy is a rare disease caused by a severe vitamin C deficiency in the diet. Due to its rarity compared to other dietary deficiencies, it is seldom recognized, resulting in a typical delay in diagnosis. This issue is more common in children with physical disabilities or poor eating habits. This study aims to examine the medical history of a healthy young individual who was unexpectedly diagnosed with scurvy.
Case description: We report a five-year-old male with hearing impairment presented to our clinic with a movement limitation in lower limbs in one week. The patient's dietary history indicated that meat, fruits, and vegetables were strictly limited. Based on the X-ray results of the right and left genu, there is evidence of spur formation accompanied by sclerosis and irregular metaphysis in the femur and tibia of both sides (known as Pelken's spur). Additionally, there are dense areas with calcification on the surface of the spur (referred to as the Frankel line), as well as reduced bone trabeculation and thinning of the outer layer of the bone (referred to as pencil thin cortex). The presence of radiographic characteristics indicated osteopenia raises suspicions of scurvy. According to the complete blood count examination, the patient had severe anemia. The patient is severely malnourished. Based on the dietary history, clinical symptoms, and radiographic evidence, scurvy was diagnosed.
Conclusion: Our case demonstrates the importance of emphasizing the need for dietary screening to reduce over-examination in patients with non-specific complaints.
The effectiveness of botulinum toxin injection for reducing hypertrophic scar after cleft lip surgery
Authors: Yatindra Ida Ayu Cempaka Dewi , Samsarga Gede Wara
Published: September 2024

Introduction: The most frequent complication after cleft lip surgery is HTS. This condition leads to lip asymmetry as the scar contracts, leading to a shortened lip and nasal deformity on the affected side, impaired speech development, and psychological stress. Botulinum toxin injection is known as HTS treatment. Therefore, this systematic review aims to postoperatively establish the physical outcome of cleft lip scar in patients injected with botulinum toxin.
Method : The systematic review was conducted based on the PRISMA guidelines and PICO criteria. The experimental group was patients given botulinum toxin injections, and the control group was a placebo group. The results were based on the physical effects. This study was assessed with Cochrane risk-of-bias assessment tools. Five studies met the criteria.
Results: Physical outcomes were significantly improved using the Vancouver Scar Scale criteria, while two studies explained no significant difference in the scar scale. The consistent results were from the scar width measurement. The experimental group's scar was narrower than that of the control group. Two studies added a visual analog scale with better results in the experimental groups. Compared with standard saline injection, botulinum toxin injection has a better outcome. This result was aligned with the results found in several previous studies.
Conclusions: Botulinum toxin can promote wound healing pre or postoperatively and has narrower effects than in control groups. This study showed that overall physical outcome improved in botulinum injection for the cleft lip’s surgical scars. However, there is still a need for broader-scale studies on this topic for more reliable results.
Relationship between hypospadias type, age at surgery, and inflammatory index with hope score in hypospadias patients
Authors: Hery Poerwasusanta  , Adiatma Riz Sanfebrian , Meitria Syahadatina Noor  , Agung Ary Wibowo  , Hendra Sutapa  , Gusasi Sulandri , Edi Hartoyo
Published: September 2024

Introduction: Hypospadias is a congenital anomaly of the anterior urethral opening of the penis, curved penis, and penile foreskin posterior to the penis. Hypospadias occurs in 0.4-8.2 out of 1000 babies. The aim of hypospadias surgery is to restructure the glans into a cone and straighten the penis into a slit calibre with a meatus at the top. The purpose of this research is to assess the association between the HOPE score in Hypospadias patients in Banjarmasin and the kind of hypospadias, age at surgery, NLR, and PLR.
Methods: This research used a cross-sectional design and observational analysis. The sampling used in the study was all population members with a hypospadias diagnosis according to specific criteria and through sample approval. The analysis was univariate and bivariate with the Chi-Square and Mann-Whitney tests. The significant p-value was  <0.05.
Results: Thirty-eight patients diagnosed with hypospadias showed a relationship between hypospadias type and HOPE score with a p-value of 0.001, age at the surgery with a HOPE score p-value of 0.267, NLR with a HOPE score p-value of 0.896, and PLR with HOPE score p-value of 0.089.
Conclusion: The variable associated with the HOPE score in patients with hypospadias is the type of hypospadias.
Fahr disease pada pasien polineuropati diabetikum: Laporan kasus
Authors: Sunaryo Cornelius , Sunaryo Utoyo , Habibie Rizki , Andriani Nurvia
Published: September 2024

Introduction: Fahr disease is a rare disease that affects less than one in a million people. Calcification in the basal ganglia region is the hallmark of Fahr disease. Genetic mutations or, secondarily, other systemic diseases such as hypoparathyroidism are the root cause of this condition. This case reports Fahr Disease in a patient with diabetic polyneuropathy.
Case Report: A 70-year-old male with complaints of weakness in both legs, right hand trembling, muscle weakness, and a history of uncontrolled diabetes mellitus. On neurological examination, there was a coordination system disorder. Serologic examination results showed Hba 1C levels >14%. CT scan of the brain showed bilateral symmetrical extensive calcifications in the basal ganglia in the left cerebellum.
Conclusion: Fahr Disease was discovered based on clinical findings accompanied by CT scan results showing calcification in the brain. The prognosis of this disease is undetermined, so regular evaluation is needed to assess the progression of this disease.
 
Pendahuluan: Fahr disease merupakan penyakit langka yang diderita pada kurang dari satu per satu juta penduduk. Kalsifikasi di daerah ganglia basalis merupakan tanda dari Fahr disease. Mutasi genetik atau sekunder oleh penyakit sistemik lain seperti hipoparatiroidisme merupakan penyebab dari penyakit ini. Pada kasus ini melaporkan tentang Fahr disease pada pasien dengan polineuropati diabetikum.
Presentasi kasus: Laki-laki berusia 70 tahun dengan keluhan lemah pada kedua kaki, tangan kanan gemetar, kelemahan otot, dan riwayat diabetes melitus yang tidak terkontrol. Pada pemeriksaan neurologi terdapat gangguan sistem koordinasi. Hasil pemeriksaan serologi didapatkan kadar Hba1c >14%. CT scan otak menunjukkan kalsifikasi luas simetris bilateral pada basal ganglia di serebelum kiri.
Kesimpulan: Fahr disease ditemukan berdasarkan temuan klinis disertai dengan hasil CT scan yang menunjukkan adanya kalsifikasi pada otak. Prognosis penyakit ini belum dapat ditentukan, sehingga perlu dilakukan evaluasi secara berkala untuk menilai perkembangan penyakit ini.
Importance of Indonesian National Standard (SNI) Helmet Usage in Preventing Maxillofacial Injury among Motorbike Drivers in Indonesia: A review
Authors: Samsarga Gede Wara , Sudarsa Shita Diwyani , Suyata Astrinita Lestari , Parikesit Kiagus Handrian
Published: September 2024

Traffic accidents are one of the main etiological factors of maxillofacial injuries, with an incidence of around 34.42% to 80.14% of all bone and soft tissue injuries in the facial area. Legal institutions have made it mandatory to use protective equipment when driving, including wearing a helmet for motorcyclists. Indonesia has created special standards for helmets, the Indonesian National Standard (SNI) that should be worn when riding a motorbike. This review aims to determine the benefits of using a helmet, especially with SNI standards in preventing maxillofacial injuries.
Legal institutions have made it mandatory to use protective equipment when driving, including wearing a helmet for motorcyclists. Good helmets have the Significances Helmets Standard, such as the Indonesian National Standard (SNI). It is used according to standard procedures, including attaching a strap, being healthy, and not riding when drunk and sleepy. Indonesian National Standard (SNI) helmets are technically designed to meet safety standards and protect motorcyclists' heads when involved in an accident. Many studies consistently show the benefits of using a helmet to prevent head injuries and reduce the death rate and severity of injuries in motorcyclists. The findings of this study may be related to previous studies in which riders wearing full-face helmets experienced an increased incidence of mid-face injuries. Good regulation for SNI helmet usage in Indonesia is mandatory to avoid and minimize incidents, morbidity, and mortality of maxillofacial fracture injury in Indonesia.
Tatalaksana Terkini Skar Atrofi: Sebuah Tinjauan Literatur
Authors: Darmaputra I Gusti Nyoman
Published: September 2024

Scars are the culmination of the natural healing and reparative process resulting from the formation of dermal fibrotic scars following inflammation. Atrophic scars are widely characterized by generalized skin atrophy resulting in the loss of skin cells in the epidermis, clinically appearing as the loss of normal dermis. Atrophic scars occur more frequently than hypertrophic and keloid scars, with a ratio of 3:1.9. Atrophic scars present a significant challenge for reconstructive specialists, thus becoming a topic worthy of continuous study based on the latest consensus. The management of atrophic scars is differentiated based on the type of scar. Atrophic acne vulgaris scars can be treated with Resurfacing and Tightening techniques, Dermal Lift, dermal volumization, or combination therapy. Striae alba atrophic scars can be addressed using a combination of jet volumetric remodeling (JVR) with fractional laser. Burn atrophic scars can be treated using ablative and non-ablative laser techniques. Atrophic scars can be prevented by assessing risk, optimal wound care, and selecting surgical techniques appropriate for the type of scar.
 
Skar adalah hasil akhir dari proses penyembuhan dan reparatif alami sebagai akibat dari pembentukan skar fibrotik dermal pasca peradangan. Skar atrofi secara luas digambarkan dengan adanya atrofi kulit umum yang mengakibatkan hilangnya sel-sel kulit di epidermis yang secara klinis tampak sebagai hilangnya dermis normal. Skar atrofi lebih sering terjadi dibanding skar hipertrofi dan keloid, dengan rasio 3:1.9. Skar atrofi menghadirkan tantangan yang signifikan bagi spesialis rekonstruksi, sehingga menjadi topik yang patut dipertimbangkan untuk terus dikaji secara kontinyu berdasarkan konsensus terbaru. Tatalaksana skar atrofi dibedakan berdasarkan jenis skar. Skar atrofi akne vulgaris dapat diberikan terapi dengan teknik Resurfacing and Tightening, Dermal Lift, volumisasi dermal maupun terapi kombinasi.  Skar atrofi striae alba dapat menggunakan kombinasi jet volumetric remodeling (JVR) dengan laser fraksional. Skar atrofi luka bakar dapat menggunakan teknik laser ablatif dan non-ablatif. Skar atrofi dapat dicegah dengan menilai risiko, perawatan luka yang optimal dan pemilihan teknik pembedahan yang sesuai dengan jenis skar.
Reaksi erupsi obat eksantematosa karena ciprofloxacin
Authors: Wahyuni Anak Agung Candra , Pradnyandari Ida Ayu Cintya , Pemayun Tjokorda Dalem
Published: September 2024

Background: Exanthematous drug eruption is a skin disease induced by drugs and mediated by a type IV hypersensitivity reaction. The characteristic features are erythema macules and multiple morbilliform papules that spread rapidly, widely, and confluently.
Case illustration: A 32 year old woman came to the Emergency Unit Wangaya Regional General Hospital with complaints of reddish spots on her face, neck, chest, stomach, arms, and legs since 5 days before entering the hospital. Complaints accompanied by itching all over the body. The patient has a history of taking the antibiotic ciprofloxacin 3 days ago. In the facial region, anterior thoracic region, abdominal region, antebrachia region, dorsum pedis region, there are multiple erythema macules and papules with generalized and confluent distribution.
Conclusion: The diagnosis of extanthematous drug eruption is made based on the history and physical examination. The main treatment is identifying and stopping the use of the causative drug. Another therapy is pharmacological therapy which is symptomatic. In this case, the patient is given systemic corticosteroids, antihistamine therapy, topical corticosteroids, and antibiotics.
 
Latar Belakang: Erupsi obat eksantematosa adalah salah satu penyakit pada kulit yang diinduksi oleh obat dan dimediasi oleh reaksi hipersensitivitas tipe IV. Gambaran karakteristik yang khas berupa makula eritema dan papul multipel morbiliformis, menyebar dengan cepat dan luas serta konfluens.
Ilustrasi kasus: Seorang wanita berusia 32 tahun datang ke Unit Gawat Darurat, Rumah Sakit Umum Daerah (RSUD) Wangaya dengan keluhan bintik-bintik kemerahan pada wajah, leher, dada, perut, lengan dan kaki sejak 5 hari sebelum masuk rumah sakit. Keluhan disertai rasa gatal di seluruh tubuh. Pasien memiliki riwayat mengonsumsi antibiotik ciprofloxacin 3 hari yang lalu. Pada regio facialis, regio thorakalis anterior, regio abdomen, regio antebrachia, regio dorsum pedis terdapat macula dan papul eritema multipel dengan distribusi generalisata dan konfluens.
Simpulan: Diagnosis erupsi obat ekstantematosa ditegakkan berdasarkan anamnesis dan pemeriksaan fisik. Penatalaksanaan utama adalah mengidentifikasi dan menghentikan penggunaan obat pennyebab. Terapi lainnya adalah terapi farmakologi yang bersifat simptomatik. Dalam kasus ini pasien diberikan terapi kortikosteroid dan antihistamin sistemik, serta kortikosteroid dan antibiotik topikal.
Riwayat adiksi internet pada anak dengan skizofrenia: laporan kasus
Authors: Kartika Dewa Ayu Bintang , Basudewa I Dewa Gede
Published: September 2024

Background: Internet addiction is excessive use of the internet by individuals. Internet addiction is characterized by several symptoms in the form of compulsive symptoms, withdrawal symptoms and tolerance symptoms. There are few reported cases of internet addiction in children, especially children with special needs or mental disorders such as schizophrenia.
Case Description: A 14 year old boy came to the Bali Provincial Mental Hospital with complaints of rage and was diagnosed with schizophrenia. During the treatment period, it was discovered that one of the factors that caused the patient to go berserk was that he was not given a gadget to play on the internet. The patient's mood during the initial period of treatment appeared irritable. The patient was given therapy with Quetiapine 2x200mg, Depakote 3x250mg, and Haloperidol 2x2.5mg.
Conclusion: After carrying out an examination using the Internet Addiction Diagnostic Questionnaire, the result was 167, namely Internet Addiction and the results of the Internet Addiction Test (IAT) were moderate Internet addiction.
 
Latar Belakang: Kecanduan internet adalah penggunaan internet yang dipakai berlebihan oleh individu. Kecanduan internet ditandai oleh beberapa gejala berupa compulsive symptom, withdrawal symptom dan Tolerance symptoms. Sedikit kasus yang dilaporkan mengani adiksi internet pada anak terutama pada anak berkebutuhan khusus atau dengan gangguan mental seperti skizofrenia.
Deskripsi Kasus: Anak laki-laki, 14 tahun datang ke Rumah Sakit Jiwa Provinsi Bali dengan keluhan mengamuk dan didiagnosa dengan Skizofrenia. Dalam masa perawatan didapatkan salah satu faktor yang membuat pasien mengamuk adalah tidak diberikan gadget untuk bermain internet. Mood pasien selama masa awal perawatan tampak irritable. Pasien diberikan terapi dengan Quetiapine 2x200mg, Depakote 3x250mg, dan Haloperidol 2x2,5mg.
Simpulan: Setelah dilakukan pemeriksaan menggunakan Kuisioner Diagnostik Adiksi Internet didapatkan hasil 167 yaitu Kecanduan Internet dan hasil Internet Addiction Test (IAT) adalah kecanduan internet sedang.
Renal cell carcinoma in a supernumerary left kidney: A very rare case report
Authors: Prayuda Yoga Eka , Haq Rais Syaeful
Published: September 2024

Introduction: The supernumerary kidney, the rarest urinary tract anomaly, typically presents as an asymptomatic third kidney. Renal cell carcinoma constitutes 90% of kidney cancer cases. Supernumerary kidneys are often incidentally discovered via imaging. Management depends on symptoms, with nephrectomy for nonfunctioning kidneys. Only three cases of supernumerary kidney carcinoma are reported. This report aims to report a case of renal cell carcinoma of the left supernumerary kidney discovered intraoperatively.
Case report: A 56-year-old woman presented with abdominal enlargement and left flank pain for three months. A palpable lump was found, and a contrast-enhanced CT scan revealed a solid mass at the upper pole of the left kidney with suspected metastasis. During surgery, a large mass was found, leading to a radical nephrectomy. Postoperative recovery was challenging; the patient was moved to intensive care, but her condition worsened, and she died. The pathological diagnosis was clear cell renal cell carcinoma.
Conclusion: The incidence of renal cell carcinoma in the supernumerary left kidney is exceedingly rare. Intraoperative findings were different from those observed preoperatively. Radiological assessment is necessary to understand the blood supply, anatomical variations, and associated problems to prevent unnecessary surgery and the associated risk of complications.
Association of protein intake with neutrophil gelatinase-associated lipocalin (NGAL) in adult critically ill patients
Authors: Ardi Laurencia , Wulandari Yohannessa , Jusman Sri Widia A.
Published: September 2024

Nutritional support is very important for critically ill individuals considering that in this condition there are quite large metabolic changes. The American Society of Parenteral and Enteral Nutrition recommends an adequate protein diet in the early stages of severe illness. Critically ill patients experience inflammation and organ failure, resulting in elevated levels of neutrophil gelatinase-associated lipocalin (NGAL). NGAL has gained significant attention for its potential utility as an early predictor of specific organ injury and response to inflammation. Therefore, this narrative review aims to comprehensively explore the existing literature regarding the association of protein intake with NGAL levels in adult critically ill patients.
The literature study method with online-based scientific databases on research engines, including Google Scholar, PubMed, Nature, and ScienceDirect, is used in this study. From this investigation, it was found that adequate protein consumption was linked to considerably lower hospital mortality rates, duration of hospitalization, and may lower NGAL levels in patients in critical condition. Based on the review of data in previous studies, it was shown that a lower protein intake at the beginning and at the mid-end of treatment may be beneficial, providing actionable insights for the care of critically ill patients.
Current understanding and future directions in diagnosis and treatment in breast asymmetry: a literature review
Authors: Diwyani Sudarsa Shita , Suyata Astrinita Lestari , Samsarga Gede Wara , Putri Anak Agung Istri Ayu Detritha Sarasmartha
Published: September 2024

Breast asymmetry can be caused by hormonal fluctuations, surgery, or developmental abnormalities that result in disparities in the size, shape, or location of the breasts. When it comes to identifying and assessing asymmetry, diagnostic techniques such as mammography, ultrasonography, MRI, and 3D tomosynthesis provide clear advantages. To address both functional needs and aesthetic concerns, there are various treatment options available, including non-surgical techniques such as hormone therapy and fat grafting, as well as surgical techniques such as augmentation, reduction, and mastopexy. With the help of AI and machine learning, future advancements in imaging improve the accuracy of diagnoses, enabling customized treatment plans based on molecular and genetic profiles. The field is evolving due to advancements in minimally invasive, 3D-printed implants enabling customization, and regenerative therapies such as stem cell treatments, with the goal of optimizing outcomes while minimizing recovery time and complications. Non-surgical alternatives such as focused ultrasound and injectable fillers provide additional choices for patients preferring less invasive treatments. Holistic patient care integrates virtual reality for surgical planning and psychosocial support, ensuring comprehensive management of both physical and emotional aspects. Overall, ongoing innovations are poised to revolutionize breast asymmetry management, offering tailored solutions that improve patient outcomes and quality of life.
Antibacterial activity of Balinese Traditional Herbs Elephantopus Scaber Linn and Curcuma aeruginosa Roxb against Burkholderia pseudomallei, Staphylococcus aureus, and Salmonella typhimurium
Authors: Santoso Putu Nia Calista , Sari Ni Luh Putu Eka Kartika , Dewi Sri Ratna
Published: September 2024

Background: Herbal medicinal plants are considered one of the sources for new types of antibiotics due to their secondary metabolite that may have antibacterial effects. Tapak Liman (Elephantopus scaber linn) and Temu Ireng (Curcuma aeruginosa roxb) are two medicinal plants that have potential as antibacterial agents due to their secondary metabolite contents. This study aimed to investigate the secondary metabolite contents of tapak liman and temu ireng grown locally in Bali and their antibacterial activity against Burkholderia pseudomallei, Staphylococcus aureus, and Salmonella typhimurium.
Methods: This post-test experimental research was conducted from June to December 2021 at the Universitas Warmadewa Faculty of Medicine and Health Sciences Research Laboratory. Tapak liman leaves and temu ireng rhizomes, sourced from a local garden in Denpasar, Bali, were used. Ethanolic extracts of these plants were tested for secondary metabolites and their antibacterial activity against Staphylococcus aureus, Salmonella typhimurium, and Burkholderia pseudomallei.
Results: A phytochemical analysis of tapak liman from Denpasar shows that it contains alkaloids and phenols, while temuireng contains flavonoids, tannins, and phenols. Antibacterial tests revealed that both plants have a weak effect against gram-positive Staphylococcus aureus but negligible effect against gram-negative Burkholderia pseudomallei and Salmonella typhimurium.
Conclusion: Both tapak liman and temu ireng ethanolic extract have weak antibacterial properties against gram-positive Staphylococcus aureus and negligible/no antibacterial properties against gram-negative Burkholderia pseudomallei and Salmonella typhimurium.
Relasi Penafsiran Amin Al-Khuli tentang Puasa dalam Al-Quran dengan Kondisi Sosiologi dan Psikologi
Authors: Ridlo Muhammad Abdurrasyid , Amanaturrahman Amanaturrahman , Kholis Iskandar
Published: September 2024

The literary exegesis of the Qur'an developed by Amin Al-Khuli offers a new approach to interpreting the sacred text as a response to critiques of classical exegesis and modern cultural and intellectual developments. This study aims to explore the evolution of Qur'anic interpretation in the contemporary era, with a focus on Amin Al-Khuli’s literary exegesis of the verses on fasting and its relevance to the sociological and psychological conditions of Muslims who fast. The research uses a qualitative approach with library research methods, where data is gathered through literature review and analyzed using techniques of inventory, classification, and interpretation. The findings reveal that Al-Khuli’s literary exegesis provides a deeper and more contextual understanding of the fasting verses, linking the aspects of language and Qur'anic meaning with contemporary social and psychological conditions. The conclusion of this research is that the literary exegesis approach not only enriches the understanding of the text but also offers practical solutions to the challenges faced by Muslims in fasting practices. Recommendations for future research include conducting field studies to collect more empirical data and exploring the integration of literary exegesis with other interpretive approaches for broader application in Muslims' daily lives.
Biunivocidad y monorreferencialidad en la realidad financiera. Variación y preferencia de uso de los términos financieros
Authors: Picazo-Izquierdo Alicia
Published: September 2024

La traducción especializada desempeña un papel crucial en los ámbitos profesionales. Una óptima comunicación interlingüística es necesaria para la comprensión de la realidad económica y financiera en distintos países. En este proyecto, se plantea la duda de si se cumple en la práctica el principio de biunivocidad y monorreferencialidad propio de los términos especializados. Se analiza una serie de términos con un alto nivel de abstracción y especialización, y que se emplean en finanzas. Para ello, se compila un corpus de textos de distintas entidades financieras en español e inglés, de forma que sea posible comparar el mismo concepto in vivo en ambos idiomas y en el mismo contexto. De esta forma, se comprueba si en todas las entidades financieras se ha utilizado el mismo término o si existe variación. Como en varios términos se produce variación denominativa o semántica, se analizan en profundidad para diferenciar las causas.
Effect of the brass waste recycling process on mechanical properties with investment casting for gear materials
Authors: Erwin Erwin , Sugiyanto Didik , Faturahman Danny , Chan Yefri , Asbanu Husen
Published: September 2024

This study is an experimental research to analyze the characteristics and mechanical properties of the casting process of recycled brass alloy, which will be used as a material for gears. Currently, the remaining production and waste from brass alloys continue to increase. Another thing is the increase in the need for brass gears, so environmentally friendly material engineering is needed to provide good quality and efficient energy use, especially during the casting process. The casting process uses an electric furnace that melts brass alloys at 526 up to 900 °C within 1 hour and molds to make test specimens. The results of microstructural testing for grain size in recycled brass alloys range from 74.63 μm to 84.57 μm. The maximum tensile strength produced is up to 225.2 MPa, the maximum yield strength is up to 179.8 MPa, and the maximum elongation is up to 7.3 %. The roughness of recycled brass alloys has a maximum Ra value (average roughness) of up to 0.836 μm. Validation was carried out by comparing the mechanical properties of CAC 302 brass products and the study results. The data shows that recycled brass's maximum yield strength value is 179.8 MPa and CAC 302 brass material is 175 MPa, but for the ultimate tensile strength value, the value of recycled brass is far below CAC 302 products. These results can be a consideration for the industry to be able to use recycled brass alloys for gear products because the yield strength value is not far from CAC 302 brass products. The impact result of this study produces recycled brass alloys that are environmentally friendly, efficient in smelting energy consumption, and have good yield strength. The results of this research can benefit the manufacture of gear components made of brass alloys.
Identifying patterns and mechanisms of AI integration in blockchain for e-voting network security
Authors: Jumagaliyeva Ainur , Abdykerimova Elmira , Turkmenbayev Asset , Serimbetov Bulat , Muratova Gulzhan , Yersultanova Zauresh , Zhiyembayev Zhomart
Published: September 2024

The study focuses on the enhancement of e-voting blockchain network security through the integration of artificial intelligence. The critical problem addressed is the existing limitations in real-time threat detection and anomaly detection within blockchain transactions. These limitations can compromise the integrity and security of blockchain networks, making them vulnerable to attacks and fraudulent activities.
The core results of the research include the development and implementation of sophisticated AI algorithms designed to enhance the monitoring of blockchain transactions and the auditing of smart contracts. These AI-driven advancements introduce unique features, such as the capability to detect and respond to security threats and anomalies in real-time. This significantly strengthens and optimizes the security frameworks of blockchain systems in e-voting. These results are explained by the strategic application of machine learning and natural language processing methodologies. By employing these advanced AI techniques, the study has achieved more accurate and efficient threat detection, thereby addressing the security challenges previously mentioned.
The practical applications of these findings are extensive and diverse. Enhanced security mechanisms can be utilized in financial transactions, supply chain management, and decentralized applications, providing a robust framework for improved blockchain-based e-voting security. In conclusion, integrating AI into blockchain security mechanisms addresses current limitations in threat detection and offers a scalable and effective solution for future security challenges
Comparison of the hardness value and microstructure of Al6061 in horizontal centrifugal casting with and without mold cooling
Authors: Suprapto Agus , Tsamroh Dewi Izzatus , Andrijono Djoko , Maswain Septian Dwi Irianto
Published: September 2024

The object of this research is the horizontal centrifugal casting process of the Al6061 alloy. Usually, cast products experience some casting defects, so the horizontal centrifugal casting process is applied to reduce the possibility of casting defects arising. In some casting processes, especially in the production of cylindrical specimens, casting defects such as porosity are encountered. Therefore, horizontal centrifugal casting was applied to overcome this problem. The test results show that the average hardness value for aluminum 6061 specimens resulting from centrifugal casting products with water cooling was 73.3 HRE, while the average hardness value for aluminum 6061 specimens resulting from centrifugal casting products without water cooling was 86.4 HRE. The microstructure results show that the grain size of centrifugal casting products with water cooling was 82.5 µm, whereas without water cooling it was 75 µm. Higher hardness values were obtained in specimens without mold cooling, this is because the conductivity in molds without cooling was higher compared to molds that experienced water cooling. The higher the heat conductivity of the mold, the faster the cooling process of the cast product. The casting process using the horizontal centrifugal method can be carried out to produce cylindrical spare parts
Assessing the efficiency of the effect of innovations on the development of grain processing enterprises
Authors: Yessakhmetova Lyailya , Dzholdasbaeva Gulnar , Saurukova Ainura , Sauranova Meruert , Alibekova Aigul
Published: September 2024

This study evaluates the impact of the introduction of deep grain processing on the development of grain processing enterprises. The main problems of processing grain crops in the Republic of Kazakhstan have been considered. The need to assess the impact of the innovative process of enterprise development was outlined. The research was carried out in the North-Kazakhstan region; the object of the study was the grain processing industries in the North-Kazakhstan region.
The results show the following:
1) total cost savings when expanding the level of gluten consumption (up to 3 % by weight of the volume of flour consumed) will save USD 18.5 billion. The savings are due to the significant improvement in the baking properties of the flour when adding 1−3 % gluten to the level of the highest quality wheat flour. At the same time, due to the manufacturability of the process and the use of the lowest quality raw materials, the unit cost of gluten in terms of protein is lower than the price of high-quality wheat necessary for baking;
2) in the processing of starch and amino acids, grain starch is the main product of world trade among all goods of the grain processing industry, and gluten ranks only second in terms of world imports. The share of issued patents in the area of starch production is also leading among the sectors of deep grain processing;
3) the implementation of the developed project for deep processing of grain in Northern Kazakhstan could significantly improve the indicators of innovative development of the country: the increase in innovative products of the manufacturing industry in the country as a whole would be 19.1 %. The growth of non-resource exports would equal 1.5 %. The annual increase in the enterprise's revenue could be about USD 0.47 per USD 1 of investment costs compared to the base scenario for the sale of unprocessed wheat.
The scope of practical application of the results extends to the grain industry. The project has a significantly wider range of manufactured products and is focused on the markets of neighboring countries, which could reduce export risks to a minimum and provide stable demand for the company’s products
Devising a technology for obtaining glued sausage casings from intestinal raw materials using electrophoresis
Authors: Pak Andrey , Оnishchenko Vyacheslav , Yancheva Maryna , Grynchenko Nataliya , Pak Alina , Inzhyyants Samvel , Оnyshchenko Аrtem
Published: September 2024

The object of research is the technique for obtaining glued sausage casings, in which adhesive related structures and electrophoresis for tanning are used to glue the layers of intestinal raw materials.
Devising a technique for gluing sausage casings from intestinal raw materials with the use of adhesive related structures by stitching by tanning, via intensified electrophoresis, has been substantiated.
The technology of glued sausage casings from intestinal raw materials, which are classified as unclaimed residues and waste, has been proposed. The technology differs from known similar technologies by applying a technique for gluing intestinal membranes using an adhesive related construct and electrophoresis during tanning. The devised gluing technique and the device for its implementation make it possible to avoid violation of the integrity of the raw material, are universal in relation to it, and are easy to operate.
The rational parameters of electrophoresis, which is used to accelerate the tanning process of the place of gluing of the layers of the intestinal membranes using an adhesive related construct, have been determined. The potential difference between the electrodes and the duration of exposure of the gluing site for gluing the original intestinal raw materials: pork belly, lamb belly, beef belly were determined. At a potential difference of 100 V, the duration of exposure of the gluing site for pork and lamb bellies is 17 minutes, and for beef bellies − 20 minutes. It is noted that the results differ in the duration of exposure of the gluing site, which is probably due to the thickness of the layer of the raw material.
The proposed technology would contribute to improving the efficiency of the technology of glued sausage casings from intestinal raw materials and could be used at enterprises for the processing of agricultural products and the meat processing industry