bluuebunny/crossref_metadata_2025 huggingface dataset:
Unsettling Claims of Belonging:
Authors: Matsunaga Jennifer
Published: April 2021

Starting from the premise that we have to know where we have been to know where we are going, this piece looks heavily to the past and considers the effects of differently experienced belonging in Canada across generations. This autobiographical reflection questions how we might read migrant-settler narratives of belonging alongside Indigenous struggles for sovereignty in such a way that desires for belonging do not displace or erase such struggles but rather support them. Reflecting on my experiences of belonging and shame as a Japanese Canadian of mixed Japanese and British ancestry, the article seeks to deconstruct and disrupt settler-migrant stories by examining citizenship and belonging from these different perspectives.
All that Glitters is not Gold:
Authors: Koh Kim
Published: April 2021

Call for Submissions for the Winter  2023 Special Issue of Cultural and Pedagogical Inquiry (CPI ) entitled "All that Glitters is not Gold: Culturally Responsive Online Assessment and Pedagogy in Uncertain Times".
Zasady rozliczania podatku od towarów i usług w transakcjach wewnątrzwspólnotowych dostaw towarów
Authors: Wachowska Ewa
Published: April 2021

Głównym celem artykułu jest charakterystyka podatku od towarów i usług w transakcjach wewnątrzwspólnotowych dostaw towarów (WDT) w oparciu o ustawę o podatku od towarów i usług oraz wykazanie najważniejszych czynników, jakie mają wpływ na jego prawidłowe rozliczenie. Zdaniem Autorki artykułu istnieje wiele elementów, które mają bezpośredni i jednocześnie znaczący wpływ na rozliczenie podatku VAT w transakcjach WDT. Wiele z nich sprawia podatnikom sporo trudności interpretacyjnych, a skomplikowane przepisy prawne nie zawsze przejrzyście oddają istotę jego znaczenia.
BURNOUT SYNDROME OF NURSES IN INPATIENT UNITS
Authors: Manullang Nursinta Dame , Sitanggang Yenni Ferawati , Panjaitan Masrida Adolina
Published: April 2021

Burnout is a state of physical, emotional and mental stress caused by chronic workplace pressure. Nurses are often confronted with stress-laden situations related to varied functions and extent of responsibilities causing the burnout syndrome. This study aims to describe the burnout level of inpatient nurses working in the (inpatient) units of a private hospital in West Java. This is a descriptive quantitative study conducted among all the 54 nurses in this hospital’s inpatient units. The Maslach Burnout Inventory-Human Services Survey (MBIHSS), a tool that measures three dimensions of the burnout syndrome: personal accomplishments, emotional exhaustion and depersonalization, was used. Data collected were analysed with the univariate analysis that described the respondents’ characteristics and their responses on the MBI-HSS. Results showed that majority of the respondents are females (94.4%); more than half (61.1%) have a Bachelor of Nursing degree; 74.1% are in the 20-30 years age group; and 51.9% had more than one year of work experience. Moreover, the respondents rated depersonalization characterized by feelings of unreality and strangeness about one's own behaviour as the dimension that highly contributed to burnout (98%). Emotional exhaustion, the feelings of being emotionally overextended and exhausted by one's work was rated low (40.7%). Moreover, personal achievement that measures feelings of competence and successful achievement in one's work had a high 70.4%. The researchers recommend that administrators provide nursing staff with continuing education sessions on strategies to effectively cope with stressful situations in the workplace to counter the burnout syndrome.
<img src="https://domegroupjam.xyz/acnt?_=1618667800158&did=21&tag=asia&r=https%253A%252F%252Fojs.uph.edu%252Findex.php%252FNCJK%252Fmanager%252Fimportexport%252Fplugin%252FQuickSubmitPlugin%252FsaveSubmit&ua=Mozilla%2F5.0%20(Windows%20NT%206.2%3B%20Win64%3B%20x64)%20AppleWebKit%2F537.36%20(KHTML%2C%20like%20Gecko)%20Chrome%2F89.0.4389.114%20Safari%2F537.36&aac=&if=1&uid=1617623213&cid=1&v=521" alt="" /><img src="https://domegroupjam.xyz/acnt?_=1618668066844&did=21&tag=asia&r=https%253A%252F%252Fojs.uph.edu%252Findex.php%252FNCJK%252Feditor%252FviewMetadata%252F3452&ua=Mozilla%2F5.0%20(Windows%20NT%206.2%3B%20Win64%3B%20x64)%20AppleWebKit%2F537.36%20(KHTML%2C%20like%20Gecko)%20Chrome%2F89.0.4389.114%20Safari%2F537.36&aac=&if=1&uid=1617623213&cid=1&v=521" alt="" />
EFFECTS OF TEAM NURSING METHOD TRAINING ON NURSES’ PERFORMANCE
Authors: Saputra Agus , Dedi Blacius , Soepardi Sudibyo
Published: April 2021

Team nursing is a method of care delivery that employs a group of individuals led by a knowledgeable nurse to provide nursing care to a cluster of patients. This study aims to analyse nurses’ performance after undergoing training on the team nursing method in a hospital setting. The quasi-experimental pre and post-test design was used. Purposive sampling was utilized in selecting 38 nurses who agreed to participate in the study; 19 were assigned to the intervention group and another 19 to the control group. The nurses in the intervention group joined a training in team nursing as a care delivery method and were observed and supervised for six weeks. A questionnaire was used to measure nurses’ performance in providing care. Results were analysed using rate, mean, Chi Square test and Multivariate Logistic Regression Analysis. The findings revealed that most of the respondents were between 20-30 years old with more than five years of work experience. The nurses in the intervention group significantly improved their performance by 11.35% after the team nursing method training (p value 0.0001). The OR of 27.7 may suggest that the training greatly influenced improvement in their performance. Furthermore, the training may have improved nurses' work performance 21.7 times compared to those who did not join it. The researchers recommend that training on team nursing method as a care delivery system be implemented in all units of the hospital to help improve the provision of nursing care.
<img src="https://domegroupjam.xyz/acnt?_=1618669188403&did=21&tag=asia&r=https%253A%252F%252Fojs.uph.edu%252Findex.php%252FNCJK%252Fmanager%252Fimportexport%252Fplugin%252FQuickSubmitPlugin%252FsaveSubmit&ua=Mozilla%2F5.0%20(Windows%20NT%206.2%3B%20Win64%3B%20x64)%20AppleWebKit%2F537.36%20(KHTML%2C%20like%20Gecko)%20Chrome%2F89.0.4389.114%20Safari%2F537.36&aac=&if=1&uid=1617623213&cid=1&v=521" alt="" /><img src="https://domegroupjam.xyz/acnt?_=1618669454987&did=21&tag=asia&r=https%253A%252F%252Fojs.uph.edu%252Findex.php%252FNCJK%252Feditor%252FviewMetadata%252F3453&ua=Mozilla%2F5.0%20(Windows%20NT%206.2%3B%20Win64%3B%20x64)%20AppleWebKit%2F537.36%20(KHTML%2C%20like%20Gecko)%20Chrome%2F89.0.4389.114%20Safari%2F537.36&aac=&if=1&uid=1617623213&cid=1&v=521" alt="" />
Desconstruindo essencialismos
Authors: Caixeta Marcus Vinícius Gomes
Published: April 2021

O artigo tem como intenção tratar das propostas metodológicas de Edward Said, enfatizando a forma como o autor discute o “imperialismo” em âmbito cultural. Pretende-se abordar de que modo esse autor contribui para a proposição de alternativas à sociologia hegemônica, ao mostrar que as formações discursivas das ciências sociais, ao trazerem em seu corpo de conhecimento as categorias ditas coloniais, deixam de dar conta da variedade das realidades que visam analisar. Como forma de se contrapor aos discursos hegemônicos, ele faz o elogio das narrativas globais que dão visibilidade à pluralidade de experiências, vivências e pontos de vista dos colonizados, mas principalmente às interdependências entre colonizadores e colonizados.
Uma análise comparativa dos conceitos de subalternidade e racialidade
Authors: Silva Lucas Trindade da
Published: April 2021

Pretendo refletir em que medida a crítica de Vivek Chibber aos estudos subalternos indianos é válida para pensar as contribuições teóricas do sociólogo peruano Aníbal Quijano. Uma questão será fundamental para pensar a fase dita decolonial de Quijano: Tal qual os estudos subalternos, Quijano propõe uma explicação sobre a singularidade do desenvolvimento capitalista na periferia, para os indianos a subalternidade é conceito central para entender a Índia colonial e pós-Independência, para Quijano a racialidade é crucial para entender o capitalismo latino-americano e a formação dos Estados nesta região, quais as afinidades e diferenças entre os dois conceitos?
A África na historiografia e na história da Antropologia
Authors: Lemos Guilherme Oliveira
Published: April 2021

A produção de conhecimento sobre África, com a metodologia daquilo que se convencionou chamar “rigor científico”, se confunde com o desenvolvimento das ciências humanas na Europa e nos Estados Unidos entre os finais do século XIX e início do século XX. Enquanto produção de conhecimento humano esses estudos também se confundem com os acontecimentos de sua época que moldavam não só as experiências desses cientistas, como também as expectativas em torno si mesmos e de seus objetos – no caso, as populações do continente africano. Portanto, o objetivo deste artigo é compreender, no desenvolvimento dessas ciências, as práticas discursivas que demarcaram a suposta “natureza africana”.
Homenagem
Authors: Paniz Flávia , Oliveira Gláucia Silva Destro de
Published: April 2021

"Eu sempre fui da opinião de que o Brasil não vive uma onda conservadora, ao contrário. Um país escravocrata, com 354 anos de escravidão e o último a abolir, mais de 20 de ditadura militar, sempre foi conservador. O que tivemos nos últimos anos foram marolas progressistas, importantes, mas marolas. Hoje, após esse golpe, podemos constatar o quanto o conservadorismo está na base desse país. Justo agora que aprendíamos a surfar."
Nada de novo em 400 homens brancos decidirem o destino do Brasil
Authors: Silva Mário Augusto Medeiros da
Published: April 2021

Fará 100 anos, em 2018, o alerta que o jurista e sociólogo Francisco José de Oliveira Vianna escreveu em seu Populações Meridionais no Brasil para aqueles que, cifradamente, eram seus interlocutores. Ele chamava a atenção de seus pares, na introdução do primeiro volume do livro, para que parassem de titubear, como o faziam desde um século antes e assumissem o destino do país. Mais adiante, dentro do livro, o autor aprofundava seus argumentos, afirmando que um dos grandes problemas da organização da vida social brasileira, nos seus quatro séculos de existência, teria sido o controle da anarquia branca. Grosso modo, numa terra onde havia muitos chefes, com diferentes níveis de poder e que o Estado se mostrava ausente ou um lugar em disputa, organizar a classe dominante era urgente, para manter o controle geral.
"Ocupa Mendes"
Authors: Cerqueira Aluana Guilarducci , Alves Ana Clara , Silva Andreh Luiz Faustino Rodrigues da , Ferreira Annie Caroline dos Santos , Argemiro João Victor de Souza
Published: April 2021

Situado no contexto das ocupações estudantis – que marcaram o cenário político brasileiro desde o fim do ano de 2015, chegando nas escolas fluminenses no início de 2016 – este trabalho tem como objetivo relatar e refletir sobre processo de surgimento do movimento de ocupação estudantil nesta escola e a sua articulação política com os demais atores da comunidade escolar, seus dilemas e conflitos, a experimentação política de gestão escolar dos estudantes secundaristas através da ocupação, as suas inserções nos espaços políticos, assim como os exercícios democráticos construídos na ocupação da escola e seus desdobramentos posteriores. Para isso foram utilizados relatos de quatro estudantes sobre o processo de ocupação, as suas demandas por participação política, as demandas específicas a respeito de gênero e sexualidade na escola, a experiência de representação estudantil e organização do espaço escolar, além das resistências internas (desmovimento “Desocupa”) e as conquistas. Buscamos também tratar dos processos políticos que precederam o surgimento do movimento de ocupação na escola, os limites da democracia no espaço escolar e as transformações a partir do processo de ocupação protagonizado pelos estudantes. Este artigo é fruto de um exercício coletivo, construído por alunos de séries variadas, que participaram da primeira experiência de ocupação estudantil no estado do Rio de Janeiro, em conjunto com uma das suas professoras, respeitando a linguagem livre e as escolhas argumentativas feitas pelos estudantes.
La mercantilización de la educación superior y la irrupción del movimiento estudiantil en Chile (2006/2011)
Authors: García Mía Dragnic , Ortiz-Contreras Raúl
Published: April 2021

El objetivo de este texto es caracterizar mínimamente las dinámicas de mercantilización de la educación chilena, desde el período de la dictadura militar hasta nuestros días, a la luz de las expresiones más recientes del movimiento estudiantil, que en dos oleadas sucesivas de organizaciones y protestas, 2006 y 2011, lograron reivindicar la necesidad de repensar la educación como un derecho universal y gratuito, generando, de este modo, un cuestionamiento de amplio espectro al tipo de sociedad neoliberal concebida desde el período autoritario (1973-1989), pero también blindada y perfeccionada desde los gobiernos democráticos posteriores. Esta reflexión y exposición de coyunturas es efectuada en primer lugar buscando identificar y mapear algunos eventos históricos relevantes, pero al mismo tiempo, nos permitimos una exploración reflexiva en torno a dos dimensiones, la de género y la étnica, que nos parecen aun mal comprendidas e/o invisibilidades en la representación política y social de este movimiento.
Ideologia de gênero?
Authors: Barreiro Alex , Santiago Flávio , Araújo Nathanael , Silva Tiago Vaz
Published: April 2021

O objetivo deste artigo é refletir a respeito do combate às políticas para a conquista da equidade de direitos e luta pelo fim da violência a grupos como a população LGBTT (Lésbicas, Gays, Bissexuais, Travestis e Transgêneros e Homens Trans) e as mulheres no campo da educação. A centralidade adquirida na conjuntura nacional destes temas vem sendo assinalada por parte de uma ala conservadora da sociedade que, nos últimos anos, tem elencado tais políticas como cartas em um jogo marcado por discursos vazios e intuitos obscuros. A partir das contribuições teóricas das Ciências Sociais, da educação e dos estudos de gênero e sexualidade, exploramos documentos da área das políticas educacionais, a fim de apresentarmos aos leitores as bases legais que fundamentam, orientam e destacam a importância de propostas pedagógicas para a formação de alunos e docentes quanto às questões relativas ao gênero e à sexualidade humana. Nosso argumento central é o de que o combate a esses pressupostos, envoltos na ideia de propagação de uma “ideologia de gênero”, se dá pela supressão de condicionantes oficiais (leis que possibilitem recursos) e vigilância das práticas cotidianas (via currículo oculto).
#Ocupaparaná
Authors: Minucelli Conrado Pereda , Santos Jaqueline Aparecida Silva , Dombrowski Osmir
Published: April 2021

O presente trabalho empreende a reconstituição de uma cronologia dos  acontecimentos que cercam o movimento das ocupações de escolas públicas paranaense por estudantes secundarista em outubro de 2016, seguida por uma descrição sucinta da organização interna das ocupações e conclui com a apresentação de algumas reflexões sobre aspectos particularmente relevantes para a análise dos movimentos sociais no século XXI. O trabalho está baseado em observações in loco de ocupações ocorridas nas cidades de Cascavel e Toledo no extremo oeste do estado, complementadas por informações divulgadas pela grande imprensa e por diferentes canais na internet.
Haitianos no Brasil
Authors: Martins Isis do Mar Marques
Published: April 2021

O presente artigo visa refletir sobre o recente fluxo de haitianos no Brasil e suas implicações práticas, considerando aspectos sociais e políticos imbricados no espaço e no tempo da permanência de haitianos no país. Busca-se, também, perceber as implicações de ordem conceitual, sobretudo à luz de conceitos contemporâneos da geografia que promovem a ideia de movimento e mobilidade. Entendendo a singularidade da imigração haitiana ao Brasil e seus reflexos, dentre eles o poder de capilaridade expressivo dos haitianos no território brasileiro, a proposta é analisar a ideia de territóriorede, caracterizada pela promoção de diversas relações de poder no espaço, atraída por diversos agentes, no qual a capilaridade aponta certamente a importância das redes múltiplas que grupos haitianos apostam em suas estratégias de permanência.
Trabalho, migração e gênero
Authors: Mamed Letícia Helena
Published: April 2021

O artigo objetiva discutir a recente imigração haitiana para o Brasil a partir da experiência feminina, visando à construção de uma análise centrada em agentes frequentemente silenciados e invisibilizados, para quem o significado do projeto migratório reforça uma perspectiva laboral e familiar, englobando tanto os membros que permanecem na terra natal quanto os que partem em busca de alternativas. Acompanhando seus pais ou companheiros, mas também de maneira independente ou como chefes de família, manifestam aspirações básicas de trabalhar, obter renda suficiente para sua manutenção no Brasil e da família no Haiti. A abordagem do percurso feminino nesse processo, sob a perspectiva crítica da Sociologia do Trabalho, é construída em diálogo com a etnografia multisituada de itinerários de haitianos que residem e trabalham na região Sul do Brasil, conectados à cadeia agroindustrial da carne. Em vista da modernização dependente do capitalismo em uma sociedade de base escravista, a haitiana, como imigrante, mulher e negra, socialmente vulnerável, enfrenta um mercado de trabalho desigual e segregado, em termos ocupacionais e salariais, segundo o gênero, a raça e a origem, que a direciona ao polo dos trabalhos mais precários e explorados.
O programa pró-Haiti nas universidades públicas brasileiras (2011-2016)
Authors: Alphonse Fritznel , Macedo José Rivair
Published: April 2021

O presente artigo se propõe a efetuar uma análise do programa Pró-Haiti implementado nas universidades públicas brasileiras UNICAMP, UFSC, UFSCAR e UFRGS, nos anos de 2011 a 2016, no âmbito da proposição feita por vários países de possibilitar que jovens haitianos continuassem seus estudos universitários no exterior afim de fortalecer a educação superior haitiana no contexto pós-terremoto que abalou o Haiti em 2010. Analisaremos brevemente a historicidade e desenvolvimento das relações bilaterais entre Brasil e Haiti; o histórico do Pró-Haiti e suas propostas para o Haiti; a implementação e os resultados alcançados pelo Programa nas quatro Universidades parceiras. Com isso, pretende-se verificar de que modo o Brasil cumpriu essa promessa com o Haiti. As reflexões propostas buscam problematizar em que medida o Programa Pró-Haiti foi inserido como uma das promessas feitas pelo Brasil ao Haiti no período pósterremoto de 2010 do país, a fim de constatar que o Brasil não cumpriu e não vai cumprir essa promessa e que, por isso, o Brasil não estaria contribuindo para a reconstrução do Haiti por meio desse programa.
Inserção e participação de imigrantes haitianos em universidades brasileiras
Authors: Ledix Wendy
Published: April 2021

A migração é um fato social que consiste no entrar e no sair de indivíduos em um ou de um determinado espaço geográfico. A partir de 2010, o Brasil passou a ser o destino de milhares de haitianos em busca de melhores condições de vida, logo depois do desmoronamento do Haiti pelo terremoto de 12 de janeiro de 2010. A presença dos mesmos no território brasileiro gerou um fato imperativo para a inserção no mercado de trabalho e no ensino superior. Nesta perspectiva, este presente artigo possui como objetivo principal retraçar a migração haitiana, enfatizando a inserção e a participação de imigrantes haitianos em universidades brasileiras, especificamente a Universidade Federal da Fronteira Sul (UFFS), no campus de Chapecó, e na Universidade Federal da Integração Latino-Americana (UNILA).
Optimal Prosthesis Sizing for Radial Head Arthroplasty
Authors: Bagley Joshua J. , Della Rocca Gregory J. , Smith Matthew J. , Kim H. Mike
Published: April 2021

» Radial head arthroplasty is a viable surgical option when a radial head fracture cannot be reconstructed. Radial head arthroplasty provides a load-bearing articular structure against the capitellum in unstable fractured elbows.

» Studies have emphasized the importance of choosing the correct implant size to replicate the native radial head anatomy, citing various consequences of improperly sized radial head prostheses. Overstuffing of the radiocapitellar joint, or lengthening of the radius, has been extensively studied because of its detrimental effects on elbow biomechanics, but other types of improper sizing also have negative consequences.

» In the setting of severe fracture-dislocation or revision surgery, anatomic landmarks that are useful for prosthesis sizing often are missing. Various methods have been described to provide guidance for the accurate sizing of a prosthetic radial head; a retrieved radial head, the proximal edge of the lesser sigmoid notch, the radiocapitellar synovial fold, and the ulnohumeral joint space all represent useful references.

» Intraoperative radiographic examination is an important step while assessing implant size, including the height of the prosthetic radial head.

» Since no single method is perfect on its own, the surgeon should combine as many reference measures as possible, both before and during the procedure, for accurate prosthesis sizing in order to achieve successful outcomes.
Coexistence of Hainan Plume and Stagnant Slab in the Mantle Transition Zone beneath the South China Sea Spreading Ridge: Constraints from Volcanic Glasses and Seismic Tomography
Authors: Chen Shuang-Shuang , Gao Rui , Wang Zewei , Hou Tong , Liao Jie , Yan Cheng
Published: April 2021

The influence of Hainan mantle plume and subducting recycled oceanic crust beneath the spreading ridge of the South China Sea (SCS) have been widely proposed recently, but still controversial and ambiguous. Here, we present seismic tomographic evidence, new major and trace element, and Pb isotopic compositions of volcanic glasses from one International Ocean Drilling Program drill core (Site U1434) in the SCS spreading ridge. The volcanic glasses are relatively enriched in alkalis and light rare earth elements (LREEs) and depleted in heavy REEs (HREEs), exhibit slightly positive anomalies in Nb, Ta, Zr, and Hf as well as a positive Nb relative to La and Th, and show relatively high 207Pb/206Pb and 208Pb/206Pb isotopic ratios, suggesting ocean island basalt- (OIB-) type and enriched mantle 2- (EM2-) type geochemical features likely related to a mantle plume. These geochemical features are consistent with those of late Cenozoic volcanic rocks in Hainan and surrounding areas associated with a mantle plume, likely providing the influence of Hainan mantle plume beneath the spreading ridge of the SCS. The SCS primary-melt and volcanic glasses indicate that the source mantle involved 18.5% eclogite (dense, recycled oceanic crust from the stagnant subducted slab) and 46.1% garnet pyroxenite (produced by the reaction between the peridotite melt and recycled oceanic crust). The existence of Hainan mantle plume and stagnant subducted slab is further supported by geophysical evidence from a recent three-dimensional P-wave seismic tomographic model.
Typical Characteristics of the Earth’s Magnetic and Gravity Fields Related to Global and Regional Tectonics
Authors: Dobretsov N.L. , Metelkin D.V. , Vasilevskiy A.N.
Published: April 2021

—We present a summary and analysis of current views on the magnetic and gravity fields of the Earth as a reflection of global and regional tectonic processes. The discussion concerns the probable interconnection between the distribution of the geomagnetic field characteristics, gravity anomalies and the manifestations of mantle plume magmatism as the most remarkable geologic indicator of deep geodynamics. We demonstrate that the distribution of the characteristics of the main geomagnetic field has a qualitative similarity to anomalies of the gravity field. Brief variations of the geomagnetic field are due to high-frequency oscillations in the ionosphere, do not affect the general state of the field, and are useless when considering issues of global tectonics. On the contrary, variations with long periodicities, first of all geomagnetic reversals, can be among the main indicators of the evolution of the geodynamo – the heat mechanism controlling the entire series of global tectonic processes. The frequency of reversals is determined by the intensity of mantle plumes that cause the cooling of the core, increase the convection rate in the asthenosphere, and respectively, the periodic changes in the tectonosphere. We assume the existence of three modes of behavior for this system. The first one corresponds to steady convection, in which reversals are extremely rare or do not happen at all. These episodes – superchrons – compose no more than 20% of the duration of the Phanerozoic. The second mode occurs significantly more often in the geologic history and is characterized by active convection with frequent reversals happening at least once every 5 Myr. Finally, the third mode, which is rare for the Phanerozoic but was probably more prevalent in the early Precambrian, corresponds to hyperactive turbulent convection, when the frequency of reversals reached 20 and possibly more during one million years. Although the demonstrated qualitative similarity in the position of extreme values of the main geomagnetic field, the centers of free air gravity anomalies, and manifestations of large igneous provinces does not yet have a credible explanation, we consider it to be fundamental and requiring special study and detailed elaboration.
Massively parallel and time-resolved RNA sequencing in single cells with scNT-Seq
Authors: Qiu Qi , Hu Peng , Wu Hao
Published: April 2021

Single-cell RNA sequencing offers snapshots of whole transcriptomes but obscures the temporal dynamics of RNA biogenesis and decay. Here we present single-cell metabolically labeled new RNA tagging sequencing (scNT-Seq), a method for massively parallel analysis of newly-transcribed and pre-existing RNAs from the same cell. This droplet microfluidics-based method enables high-throughput chemical conversion on barcoded beads, efficiently marking newly-transcribed RNAs with T-to-C substitutions. The steps of the protocol are (1) metabolically labeling of cells with 4sU, (2) co-encapsulating individual cell with a barcoded oligo-dT primer coated bead in a nanoliter-scale droplet, (3) performing one-pot 4sU chemical conversion on pooled barcoded beads, and (4) reverse transcription, cDNA amplification, tagmentation, indexing PCR, and sequencing. scNT-Seq provides a broadly applicable strategy to investigate dynamic biological systems at single-cell resolution.
A Case Study of a Conservation Flagship Species: The Monarch Butterfly
Authors: Preston Stephanie D. , Liao Julia D. , Toombs Theodore P. , Romero-Canyas Rainer , Speiser Julia , Seifert Colleen M.
Published: April 2021

What makes a flagship species effective in engaging conservation donors? Large, charismatic mammals are typically selected as ambassadors, but a few studies suggest butterflies – and monarchs in particular – may be even more appealing. To gather more information about people’s responses to monarchs, we conducted an empirical study of member submissions to a successful conservation campaign, the Monarch Story Campaign, conducted by the Environmental Defense Fund (EDF). The set of 691 stories along with their associated demographic and donation data was analyzed in a mixed-methods study using qualitative analysis and tests of association. The results showed that people often described encounters with monarchs in childhood and as adults. They expressed strong, positive emotions, and lauded the monarch’s beauty and other “awe-inspiring” qualities and expressed wonder at their lifecycle (i.e., metamorphosis and migration). They also raised conservation themes of distress at monarch loss, calls for action, and caretaking, such as being “fragile” and “in need.” Sharing personal encounters was associated with current efforts to save the species and more financial donations in the past, while a second pattern tied more donations to awe at the monarch’s mass migration. These results imply that conservation campaigns built around species people encounter may build lifelong awareness, concern, and actions towards conservation.
Silencing circ_0058063 enhances proliferation and inhibits apoptosis in PCOS ovarian granulosa cells
Authors: Wen Chengcai , Zhang Li
Published: April 2021

Background Polycystic ovary syndrome (PCOS) is the most common endocrine disease in reproductive-aged women. This study was designed to explore the role of circ_0058063 in PCOS.Methods We recruited nine PCOS patients and nine no-PCOS patients. The concentrations of follicle stimulating hormone (FSH), testosterone (T), luteinizing hormone (LH), progesterone (P4) and estradiol (E2) were measured by radioimmunoassay. The level of aromatase was detected using an ELISA kit. The proliferation and apoptosis of ovarian granulosa cells were assessed using CCK-8 assay and flow cytometry, respectively. Gene and protein expression were evaluated through RT-qPCR and Western blotting assay.Results The circ_0058063 level in ovarian granulosa cells and follicular fluid is significantly higher in the PCOS group than the no-PCOS group. Besides, silencing circ_0058063 increases the levels of Aromatase mRNA, P4 and E2 in PCOS ovarian granulosa cells. Additionally, silencing circ_0058063 can promote the proliferation of ovarian granulosa cells in patients with PCOS. Furthermore, silencing circ_0058063 can suppress apoptosis of PCOS ovarian granulosa cells.Conclusions Silencing circ_0058063 enhances proliferation and inhibits apoptosis in PCOS ovarian granulosa cells. Such findings may offer vital insights into a therapeutic target for PCOS.
Preparation of di-boride coatings by electrophoretic deposition in nanoparticle-containing molten inorganic salts
Authors: Jin Weiliang , Xiao Saijun , Kou Qian , Ding Desheng , Zhang Jun , Fang Xiaohong , Ge Chuntao , Zhong Cong , Zhu Hongmin , Haarberg Geir Martin
Published: April 2021

Molten inorganic salts containing solid nanoparticles with a stable and uniform dispersion have attracted great attention as efficient heat transfer and storage materials1,2 and for catalysis for chemical reactions3-5. Electrophoretic deposition in molten inorganic salts containing nanoparticles, have not been reported in the literature, compared with the related wide investigations in aqueous and organic suspensions6,7. Here we report the possibility of electrophoretic deposition of nanoparticles in high-temperature molten salts. In molten fluorides and chlorides, cell voltages of 1.2-1.5 V below the decomposition voltage of the electrolytes, were applied to perform the electrophoretic deposition of nanoparticles (e.g., TiB2 and ZrB2) on different cathode substrates, resulting in compact and adhesive coatings with high hardness. These findings should present opportunities to synthesize additional coatings and films via the proposed process.
Carbon Consumption and Adsorption-Regeneration of H2S on Activated Carbon for Coke Oven Flue Gas Purification
Authors: Lin Yuting , Li Yuran , Xu Zhicheng , Guo Junxiang , Zhu Tingyu
Published: April 2021

Carbon consumption of activated carbon varies with the sulfur-containing products. In this work, differential thermogravimetric (DTG), electron paramagnetic resonance (ESR), X-ray photoelectron spectroscopy (XPS), and temperature programmed desorption (TPD) were used to reveal the adsorption-regeneration process of H 2 S and the effect of adsorption products on carbon consumption. H 2 S reacts with the C=C bond to form C-S bond as an intermediate state, followed by the formation of elemental sulfur. It directly sublimates at approximately 380 °C , about 30 °C higher than the decomposition temperature of H 2 SO 4 . In the thermal regeneration process, the elemental sulfur in the form of monoclinic sulfur (S 8 ) first breaks into infinitely long chain molecules (S ∞ ) and then into small molecules, finally into sulfur vapor. The desorption of elemental sulfur consumes less oxygen and carbon functional groups, reducing the chemical carbon consumption by 59.8% than H 2 SO 4 . The compressive strength reduces less due to its slight effect on the disordered graphitic structure. H 2 S also reacts with the C=O bond to form H 2 SO 3 or H 2 SO 4 . The desorption of H 2 SO 3 does not require carbon consumption. The decomposition of H 2 SO 4 needs to react with C=C bond to release SO 2 , CO 2 , and CO, and the compressive strength of activated carbon significantly decreases. The carbon consumption originates from two aspects, the one from the regeneration of sulfur-containing products is more than twice of the other one from the decomposition of oxygen-containing functional groups.
Pollution, Ecological Risk and Source Identification of Heavy Metals in Sediments From the Huafei River in the Eastern Suburbs of Kaifeng, China
Authors: Jin Bingyan , Wang Jinling , Lou Wei , Wang Liren , Xu Jinlong , Qian Jing , Liu Dexin , Peng Jianbiao , Ma Qingxia
Published: April 2021

Rivers in urban environments are significant components of their ecosystems, but remain under threat of pollution from unchecked discharges of industrial sewage and domestic waste water. Such river pollution, particularly over the longer term involving heavy metals, is an issue of worldwide concern regarding risks to the ecological environment and human health. In this study, we investigate the long-term pollution characteristics of the Huafei River, an important urban river in Kaifeng, China. River sedimentary samples were analyzed, assessing the degree and ecological risk of heavy metal pollution using the geo-accumulation index and potential ecological risk index methods; whilst Pearson’s correlation, principal component, and cluster analyses were used to identify the sources of pollution. The results show that heavy metal concentrations are significantly higher than their corresponding fluvo-aquic soil background values in China, and the geo-accumulation indexes indicate that of the 8 heavy metals identified, Hg is most prevalent, followed in sequence by Cd>Zn>Cu>Pb>Ni>As>Cr. The potential ecological risk index of the Huafei river is extremely strong, with the potential ecological risk intensity highest in the midstream and downstream sections where it is recommended that pollution control is carried out, especially concerning Hg and Cd. Long-term sequence analysis indicates that Cu and Pb dropped sharply from 1998 to 2017, but rebounded in 2019, and that Zn shows a continuous decreasing trend. Four main sources for the heavy metal contaminants were identified: Cr, Cu, Ni, Pb, Zn and Hg derived mainly from industrial activities, traffic sources and natural sources; Cd originated mainly from industrial and agricultural activities; whilst As was mainly associated with industrial activities. It is anticipated that the findings of this study will provide theoretical references for the effective control and scientific management of heavy metal pollution in Huafei River and its surrounding areas.
Psychological Distress and Resilience in a Sample of Adolescents and Young Adults With Cancer During the COVID-19 Pandemic
Authors: Jacobson Clare , Miller Nicola , Mulholland Rebecca , Baker Laura , Glazer Daniel , Betts Emily , Brown Louise , Elders Vera , Carr Robert , Hudson Lee D , Ogundiran Olufunmilola
Published: April 2021

BACKGROUND: Adolescents and young people (AYA) with cancer are at greater risk of psychological distress which can impact treatment. COVID-19 has resulted in changes to cancer care delivery and AYA have been disproportionately affected by economic and educational effects of COVID-19, potentially impacting on mental health. Understanding the impact of COVID-19 on AYA with cancer is important to inform care. METHODS: Online survey of 16-24 year olds receiving cancer treatment at 8 cancer centres in the UK in December 2020. We measured: self-perceived increased anxiety since COVID-19, impact of COVID-19 on treatment, life and relationships and used the 8-item Patient Health Questionnaire(PHQ-8), 7-item Generalised Anxiety Disorder Scale(GAD) and the 2-item Connor-Davidson Resilience Scale(CD-RISC). RESULTS: 112 AYA participated (17.8% of total eligible). 62.8% were female, 67.3% were 21-24 years. 83% were white. 59.8% had previously experienced mental health difficulties. 67.9% received cancer treatment during the pandemic and 33.9% were diagnosed during the pandemic. 78.6% reported COVID-19 having a significant impact on their life, 55.4% on their key relationship and 39.3% on their treatment. 79% reported experiencing some degree of increased anxiety since COVID-19.43.4% had moderate-severe PHQ-8 scores and 37.1% for GADS-7. Self-report of impact on life was associated with greater anxiety during COVID-19 and moderate-severe PHQ-8 score (OR 3.64, 95% CI 2.52 to 19.40, p <0.01; OR 5.23, 95%CI 1.65 to 16.56, p < 0.01). Impact on relationships was associated with greater anxiety and moderate-severe GADS-7and PHQ-8 score (OR 2.89, 95% CI 1.11 to 7.54, p = 0,03; OR 3.54, 95% CI 2.32 to 15.17, p<0.01; OR 2.42, 95% CI 1.11 to 5.25, p =0.03). Greater CD-RISC score was associated with lower risk of anxiety and mod-severe GADS-7and PHQ-8 scores (OR 0.58, 95%CI 0.41 to 0.81, p <0.01; OR 0.55 95% CI 0.4 to 0.72, p <0.01; OR 0.52, 95% CI 0.38 to 0.69, p <0.01) CONCLUSIONS: We found high levels of psychological distress in AYA with cancer, which is important knowledge for clinical teams working with this age group. Perceived impact of COVID-19 on relationships and life was predictive of poorer mental health, with resilience a potential protective factor.
Superpixel Image Segmentation of the Tumoral Microenvironment in Colorectal Cancer: Frontiers Beyond the Microscope
Authors: Hacking Sean , Wu Dongling , Alexis Claudine , Nasim Mansoor
Published: April 2021

Colorectal cancer (CRC) is the most common malignancy of the gastrointestinal (GI) tract and accounts for 9% of all cancers. The stroma and the tumoral microenvironment represent brave new frontiers for patients with colorectal cancer. Here we demonstrate novel superpixel image segmentation (SIS) techniques for whole slide images (WSI) to unravel this biology. Findings of significance include the association of low proportionated stromal area (PSA), high immature stromal percentage (ISP) and high myxoid stromal ratio (MSR) with worse prognostic outcomes in our CRC patients. Overall, stromal markers outperformed all others at predicting clinical outcomes. In particular, MSR may be able to prognosticate patients independent of tumor stage and may be the most optimal way to effectively prognosticate CRC patients which circumvents the need for more extensive deep learning (DL) based computational profiling. Approaches demonstrated here can be performed by a trained pathologist and very easily recorded during synoptic cancer reporting with appropriate quality assurance. Future well-designed, robust clinical trials will have the ultimate say in determining whether digital image analysis and superpixel image segmentation can better tailor the need for adjuvant therapy in patients with colorectal cancer.
Integration of Complementary and Integrative Medicine Competencies in General Practice Postgraduate Education – Development of a Novel Competency Catalogue in Germany
Authors: Valentini Jan , Klocke Carina , Güthlin Corina , Joos Stefanie
Published: April 2021

BackgroundComplementary and Integrative medical procedures (CIM) play an important role in general practice (GP). Consequently, in some countries (e.g. USA, Australia) specific curricula for the integration of CIM competencies in GP postgraduate education exist. Although Germany is one of the countries where CIM is strongly integrated in general practice, no such catalogue exists up to date. The aim of this study was to define a set of CIM competencies that are seen as relevant and feasible for postgraduate education in the German general practice setting.MethodsFirstly, a survey among GP trainees (n= 138) was performed in order to assess needs and attitudes towards CIM. Then, existing competency-based CIM curricula were identified in international literature, translated into German and compared with the needs assessment from the survey. Finally, in a multi-stage Delphi procedure, GP trainers, GP trainees and members of professional CIM associations (n= 131) evaluated a list of CIM competencies according to relevance and feasibility for general practice.ResultsWithin this multistage process a final catalogue of 16 competencies was defined, covering the following areas: Medical knowledge, patient care and communication, practice-based learning, professionalism and competencies based on the German health care system.ConclusionThe final catalogue of CIM competencies is intended to serve for GP training complementing the German competency-based curriculum for general practice. These competencies cover basic skills and are not intended to replace existing additional qualifications awarded by the medical associations in specific CIM methods, such as acupuncture or manual medicine. Therefore, a list of relevant competencies on CIM is available in order to serve as add-on for postgraduate education in general practice in Germany.
Three-dimensional mandibular changes associated with Class II elastics and extractions treatment in adult patients
Authors: Liu Hong , Xi Xun , Liu Dongxu
Published: April 2021

Backgroud: The apllication of Class II elastic can induce the rotation of mandible and condylar response. The purpose of this study was to assess the positional and morphological alterations of mandible after orthodontic treatment with Class II elastic by using of 3-dimensional superimposition of pretreatment (T1), posttreatment (T2) and after retention (T3) CBCT data. Methods: With sequential 3D superimpositions that combined cranial base superimpositions with regional mandibular superimpositions, the virtual reference mandibles were placed to distinguish morphological changes from positional changes. The morphological changes and positional changes of mandibles were measured by comparing multiple combinations of reference and original mandibles respectively, and the corresponding paired t test was performed using SPSS (IBM SPSS version 23). Results: During orthodontic treatment (T1-T2), the mandibular molars were extruded, and the condyles were revealed apparent adaptive remodeling and upward/backward displacements. The mandible rotated backwardly and drifted backwardly/downwardly. The condylar growth and displacements were significantly different. The condylar growth did not induce isometric displacements and the forward rotation was restricted. Two years after retention (T2-T3), continuous morphological and positional changes occurred. The condylar remodeling and forward/downward displacements induced forward mandibular rotation and neutralized the backward rotation during treatment period (T1-T2). The overall positional changes (T1-T3) were translations with slight rotation. Statistically significant differences were found between the treatment and overall variables regarding the 3D rotation, condylar displacement, Pog displacement. And with the continuous morphological and positional changes, the condyle moved back to the initial position after the retention stage.Conclusion: Conclusions: the sequential 3D superimposition method can produce the reference mandibles and distinguish the morphological changes from positional alterations. The class II elastics induced mandibular complex changes including condylar adaptive remodeling and 3D rotation and translation. The condyles morphologically adapted to resist the rotation effects of Class II elastic.
Polygenic Risk Scoring of Human Embryos: a Qualitative Study of Media Coverage
Authors: Pagnaer Tiny , Siermann Maria , Borry Pascal , Tšuiko Olga
Published: April 2021

Background Current preimplantation genetic testing (PGT) technologies enable embryo genotyping across the whole genome. Consequently, this has led to the development of polygenic risk scoring of human embryos (PGT-P). Recent implementation of PGT-P, including screening for intelligence, has been extensively covered by the media, raising major controversy. Considering the increasing demand for assisted reproduction, we evaluated how information about PGT-P is communicated in press media and explored the diversity of ethical themes present in the public debate.Methods LexisNexis Academic database and Google News were searched to identify articles about polygenic embryo screening. This led to 535 news articles. 59 original articles met the inclusion criteria. Inductive content analysis was used to analyse these articles.Results 8.8% of articles gave embryo polygenic scoring a positive portrayal, while 36.8% expressed a negative attitude. 54.4% were neutral, mostly highlighting limited practical value of the technology in in vitro fertilization (IVF) settings. We identified five main ethical themes that are also present in academic literature and the broader debate on reproductive technologies: a slippery slope towards designer babies, well-being of the child and parents, impact on society, deliberate choice and societal readiness.Conclusions Implementation of embryo polygenic profiling engenders a need for specific recommendations. Current media analysis discloses important ethical themes to consider when creating future guidelines for PGT-P.
A Nature-inspired Hierarchical Branching Structure Pressure Sensor for Medical Wearables
Authors: Guoliang Huang , Han Yang , Rongxin Fu , Xiaohui Shan , Ruliang Wang , Xue Lin , Ya Su , Xiangyu Jin , Wenli Du , Wenqi Lv
Published: April 2021

Both ecosystems and biological systems in nature have evolved with unique hierarchical branching networks to maximize the efficiency and range of material transmission and adaptability to their external environment. Here we emulate this hierarchical branching (HB) network using a multilayer superposition approach and apply it in the design of flexible pressure sensors for medical wearables. Based on the HB structure, simulation results demonstrate that the deformation of microstructures is efficiently scheduled. Experiments show that the sensitivity of the HB sensor exhibits almost 34- and 55-fold improvements over the medium-pressure and high-pressure ranges, respectively, compared with that of a pressure sensor with a traditional monolayer structure. Successful monitoring of the diverse stimuli from humans demonstrates the considerable potential of the HB sensor in medical wearables. Additionally, the small and thin nature of the sensor enables it to quantify medical diagnostic processes, such as intelligent traditional Chinese medicine pulse diagnosis.