bluuebunny/crossref_metadata_2025 huggingface dataset:
NON-PERFORMING PROPERTY LOANS AND ITS ORIGINATION IN THE REAL ESTATE FINANCE SYSTEM: CASE STUDY OF MALAYSIA
Authors: Wei Tham Kuen , Said Rosli
Published: January 2022

A healthy real estate finance system is crucial for any economy to grow and thrive. However, in recent years, the sustainability and soundness of the Malaysian Real Estate Finance System had been in question as the number of non-performing property loans had been on the rise. This paper looks into how property NPLs originate within the real estate finance system in Malaysia and its current performance in Malaysia. A descriptive research design was conducted utilizing in-depth case studies of Malaysia to examine Malaysia’s real estate finance system consisting of loan originators in the primary market and the special purpose vehicle involved at the secondary mortgage market where it was found that the Malaysian Real Estate Finance System is efficiently developed and on par with other developed countries with a robust primary mortgage market, effective secondary mortgage market and a vibrant capital market. Further analysis found that there are a total of 57 financial institutions that are property loan originators in Malaysia that consists of 26 Commercial Banks, 16 Islamic Banks, 2 International Islamic Banks, 11 Investment Banks, and 2 Special Financial Institutions. In terms of NPLs in Malaysia, property loans are the largest component of total NPLs in the country, and subsequent analysis found that the number of property NPLs in the country had been rising since 2015, after a long decade decline. This study warrants further research into the causes of property NPLs in the country so that the causes of property NPLs can be monitored as part of the country's strategic monetary policy to control and reduce the number of property NPLs in the country. Ultimately, this also helps to contribute towards a sound and robust real estate finance system in Malaysia.
Architectural Sustainability on the Impacts of Different Air-Conditioning Operational Profiles and Temperature Setpoints on Energy Consumption: Comparison between Mosques with and Without HVLS Fan in the City Center Mosques
Authors: Mohamed Nur Amalina Syairah , Shari Zalina , Dahlan Nur Dalilah , Idowu Ibiyeye Aminat
Published: January 2022

The use of air-conditioning (AC) in conjunction with high-volume, low-speed (HVLS) fan has become a trend in retrofitted mosque buildings in Malaysia to improve thermal comfort conditions. However, the energy impact of operating AC and HVLS fan simultaneously is unknown. This study compares the annual energy consumptions between mosques with and without HVLS fan installed and investigates the optimum temperature setpoints and operational profile to improve the mosques' energy efficiency. The comparison using the Building Energy Index (BEI) did not clearly show the superiority between the two groups in terms of energy performance. The study found that both studied mosques could produce around 1-4.9% energy reduction when the AC temperature setpoint was increased by 1˚C and could result in the highest cost-saving of about 4.9% when the temperature was set at 27˚C. A 30-minute AC operation during each daily prayer, except Subuh, could save between 14.8-16.7% annual energy consumption and about 15.15-16.6% annual energy cost. The paper concludes that the selection of 24-27˚C temperature setpoints with a 30-minute AC operational profile during prayers time with consideration Friday prayers and Ramadhan activities produced 18.4-20.6% savings in energy cost. This study calls for reevaluations of AC temperature setpoints configuration standards and operational characteristics in mosque buildings to reduce the buildings' energy consumption. This paper contributes to the development of future energy standards for mosque designs and operations in Malaysia.
A case of early thrombosis following a percutaneous tricuspid valve in valve implantation managed by thrombolysis
Authors: Rahnamoun Zahra , Shojaeifard Maryam , Firouzi Ata , Sadeghipour Parham
Published: January 2022

Bioprosthetic valve thrombosis is a growing recognized entity,
especially with the increasing use of the valve in vale procedures and
the advent of new detection technologies (e.g., 4D CT and 4D
echocardiography). However, the optimal management strategy in the acute
context is not established. This paper presents a case of early
thrombosis following the percutaneous tricuspid valve in vale procedure
that was successfully managed with thrombolysis.
Uniform stability for a type III thermoelastic laminated beam with structural damping
Authors: Djellali Fayssal
Published: January 2022

In this work, we consider a thermoelastic laminated beam with structural
damping, where the heat flux is given by Green and Naghdi theories. We
establish the well-posedness of the system using semigroup theory.
Moreover, under the condition of equal wave speeds, we prove an
exponential stability result for the considered system. In the case of
lack of exponential stability we show that the solution decays
polynomially.
One-pot synthesis of high-capacity silicon anodes via on-copper growth of a semi-conducting, porous polymer
Authors: Bojdys Michael
Published: January 2022

Silicon-based anodes with lithium ions as charge carriers have the
highest predicted theoretical specific capacity of 3579 mA h
g (for LiSi).
Contemporary electrodes do not achieve this theoretical value largely
because conventional production paradigms rely on the mixing of weakly
coordinated components. In this paper, a semi-conductive triazine-based
graphdiyne polymer network is grown around silicon nanoparticles
directly on the current collector, a copper sheet. The porous,
semi-conducting organic framework (i) adheres to the current collector
on which it grows via cooperative van der Waals interactions, (ii) acts
effectively as conductor for electrical charges and binder of silicon
nanoparticles via conjugated, covalent bonds, and (iii) enables
selective transport of electrolyte and Li-ions through pores of defined
size. The resulting anode shows extraordinarily high capacity at the
theoretical limit of fully lithiated silicon. Finally, we combine our
anodes in proof-of-concept battery assemblies using a conventional
layered Ni-rich oxide cathode.
When schizophrenia is not schizophrenia: A premature diagnosis of mental illness can be serious malpractice
Authors: Diamandis Dr. Carolina , Smith Lucas , Lazar Marius , Seideman David , Tudor Adrian
Published: January 2022

The number of diagnoses of mental illness has been increasing for years,
especially in the wealthy industrialized nations. What continues to be
overlooked is the massive influence of the lobby of the
psychotherapeutic “industry”, which has long and steadily earned good
money from hastily misdiagnosed patients. However, this can be a matter
of moderate to severe malpractice.
Impact of COVID-19 Vaccination on Glycemia in Individuals With Type 1 and Type 2 Diabetes: Substudy of the COVAC-DM Study
Authors: Aberer Felix , Moser Othmar , Aziz Faisal , Sourij Caren , Ziko Haris , Lenz Jacqueline , Abbas Farah , Obermayer Anna M , Kojzar Harald , Pferschy Peter N , Müller Alexander , Unteregger Christina , Leitner Marlies , Banfic Tamara , Eckstein Max L , Wachsmuth Nadine , Kaser Susanne , Mader Julia K , Tripolt Norbert J , Sourij Harald , group the COVAC-DM study
Published: January 2022

Vaccination and potentially related side effects might impact
glucose management in people with diabetes. In this study, we
investigated effects of COVID-19 vaccination on glycemia assessed by
continuous glucose monitoring (CGM) in people with type 1 and type 2
diabetes.

 74 participants of the ongoing multicenter prospective
COVAC-DM-study, investigating the immune response to COVID-19 vaccines
in people with diabetes, were willing to participate in this CGM
sub-study. Time spent in glycemic ranges (time in range [TIR] 70-180
mg/dL; time below range [TBR] <70 mg/dL and time above range [TAR]
>180 mg/dL) was assessed daily from two days prior to three days
after the first COVID-19 vaccination. Participants were asked to
document side effects in response to vaccination, insulin injections,
and carbohydrate intake.
 58 participants with type 1 (27 female, mean age 39.5 years, HbA1c
57 ± 12 mmol/mol) and 16 with type 2 diabetes (9 females, mean age 60.6
years, HbA1c 63 ± 11mmol/mol) were included in this study. The mean TIR
did not change on the day of the vaccination and the following 3 days
(p>0.05). In people with type 1 diabetes, the TIR (p=0.033) and the
TAR (p= 0.043) deteriorated on days with side effects as compared to
those without.

 Side effects occurring after COVID-19 vaccination significantly
reduce the TIR and increase the TAR in people with type 1 diabetes,
while no impact was observed in people with type 2 diabetes.
Polygenic Prediction of Type 2 Diabetes in Africa
Authors: Chikowore Tinashe , Ekoru Kenneth , Vujkovic Marijana , Gill Dipender , Pirie Fraser , Young Elizabeth , Sandhu Manjinder S , McCarthy Mark , Rotimi Charles , Adeyemo Adebowale , Motala Ayesha , Fatumo Segun
Published: January 2022

Objective. Polygenic
prediction of type 2 diabetes in continental Africans is adversely affected
by the limited number of genome-wide association studies (GWAS) of type 2
diabetes from Africa and the poor transferability of European derived polygenic
risk scores (PRS) in diverse ethnicities. We set out to evaluate if African
American, European or multi-ethnic derived PRSs would improve polygenic
prediction in continental Africans.

Research
Design and Methods. Using the PRSice software, ethnic-specific PRSs were
computed with weights from the type 2 diabetes GWAS multi-ancestry
meta-analysis of 228,499
cases and 1,178,783 controls. The South
African Zulu study (1602
cases and 981 controls) was used as the target data set. Validation and assessment of the best
predictive PRS association with age at diagnosis was done in the Africa America
Diabetes Mellitus (AADM) study (2148 cases and 2161 controls).

 Results. The discriminatory ability of the African American and
Multi-ethnic PRS were similar. However, the African American derived PRS
was more transferable in all the countries represented in the AADM cohort, and
predictive of type 2 diabetes in the country combined analysis compared to the
European and multi-ethnic derived scores. Notably, participants in the 10th
decile of this PRS had a 3.63-fold greater risk (OR 3.63; 95%CI (2.19 - 4.03),
p = 2.79 x 10-17) per risk allele of developing diabetes and were
diagnosed 2.6 years earlier compared to those in the first decile.

Conclusions
African American derived PRS enhances polygenic prediction of type 2 diabetes
in continental Africans. Improved representation of non-European populations
(including Africans) in GWAS promises to provide better tools for precision
medicine interventions in type 2 diabetes.
Beliefs Around Hypoglycemia and Their Impacts on Hypoglycemia Outcomes in Individuals with Type 1 Diabetes and High Risks for Hypoglycemia Despite Using Advanced Diabetes Technologies
Authors: Lin Yu Kuei , Richardson Caroline R. , Dobrin Iulia , DeJonckheere Melissa J. , Mizokami-Stout Kara , Fetters Michael D. , Aikens James E. , Fisher Simon J. , Ye Wen , Pop-Busui Rodica
Published: January 2022

Objective: This study aims to: (1) identify the
frequency of severe and level 2 hypoglycemia presenting in people with type 1
diabetes using continuous glucose monitoring systems (CGMs), including those
with concomitant closed-loop insulin pumps, in a clinical practice setting; (2)
evaluate the impact of beliefs around hypoglycemia in the development of severe
and level 2 hypoglycemia in this population.

Research Design and Methods: A cross-sectional survey study in adults
with type 1 diabetes using CGMs >6 months was conducted at a large tertiary
academic center. Participant demographics, 6-month severe hypoglycemia history,
hypoglycemia beliefs (with the Attitude to Awareness of Hypoglycemia
questionnaire) and 4-week CGM glucose data were collected. Statistical analysis
was performed to assess the presentation of severe and level 2 hypoglycemia and
identify associated risk factors.

Results: A total of 289 participants were
recruited (including 257 participants with CGM data within the last 3 months). Of
these, 25.6% experienced at least one severe hypoglycemic episode in the last 6
months, and 13.6% presented with ≥1% of time in level 2 hypoglycemia on CGMs. Reporting
beliefs about prioritizing hyperglycemia avoidance was associated with severe hypoglycemia
development (P<0.001), while having beliefs of minimal concerns for
hypoglycemia was associated with spending ≥1% of time in level 2 hypoglycemia (P=0.038).

Conclusions: Despite the use of advanced diabetes
technologies, severe and level 2 hypoglycemia continues to occur in people with
type 1 diabetes and high hypoglycemia risks. Human factors, including beliefs
around hypoglycemia, may remain to impact the effectiveness of glucose
self-management.
Surveillance of atypical femoral fractures in a nationwide fracture register
Authors: Bögl Hans Peter , Zdolsek Georg , Barnisin Lukas , Möller Michael , Schilcher Jörg
Published: January 2022

Background and purpose — To continuously assess the incidence of atypical femoral fractures (AFFs) in the population is important, to allow the evaluation of the risks and benefits associated with osteoporosis treatment. Therefore, we investigated the possibility to use the Swedish Fracture Register (SFR) as a surveillance tool for AFFs in the population and to explore means of improvement.
Patients and methods — All AFF registrations in the SFR from January 1, 2015 to December 31, 2018 were enrolled in the study. For these patients, radiographs were obtained and combined with radiographs from 176 patients with normal femoral fractures, to form the study cohort. All images were reviewed and classified into AFFs or normal femur fractures by 2 experts in the field (gold-standard classification) and 1 orthopedic resident educated on the specific radiographic features of AFF (educated-user classification). Furthermore, we estimated the incidence rate of AFFs in the population captured by the register through comparison with a previous cohort and calculated the positive predictive value (PPV) and, where possible, the inter-observer agreement (Cohen’s kappa) between the different classifications.
Results — Of the 178 available patients with AFF in the SFR, 104 patients were classified as AFF using the goldstandard classification, and 89 using the educated-user classification. The PPV increased from 0.58 in the SFR classification to 0.93 in the educated-user classification. The interobserver agreement between the gold-standard classification and the educated-user classification was 0.81.
Interpretation — With a positive predictive value of 0.58 the Swedish Fracture Register outperforms radiology reports and reports to the Swedish Medical Products Agency on adverse drug reactions as a diagnostic tool to identify atypical femoral fractures.
Skin lesions associated with personal protective equipment in medical workers during the COVID-19 pandemic
Authors: Galimova N. I.
Published: January 2022

Aim. Analysis of the incidence of personal protective equipment (PPE)-associated dermatoses among medical workers during the COVID-19 pandemic.

Materials and Methods. Screening of the papers indexed by PubMed, EMBASE, Google Scholar, eLibrary, and UpToDate databases, written in English and published from January 1, 2020 to October, 2021. The search keywords were: "medical workers", "skin", "dermatoses", "professional", and "personal protective equipment" in combination with "COVID-19" and "SARS-CoV-2".

Results. Occupational contact dermatitis is responsible for 20% of all cases of contact dermatitis which accounts for 90% of all skin disease cases. During the COVID-19 pandemic, from 42.8% to 97.0% of medical workers reported about skin lesions provoked by prolonged wearing of PPE in combination with regular disinfection. About 61.7% of them noted the deterioration of a pre-existing skin disease, and 90.5% reported the appearance of new skin lesion symptoms associated with the PPE usage. The most common symptoms of skin lesions among medical workers were dryness, itching, burning, soreness, and skin rash. Irritant and allergic contact dermatitis, acne, rosacea, and seborrheic dermatitis were the most prevalent skin disorders among the interviewed medical workers. Risk factors for the development of PPE-associated dermatoses were the type and material of PPE, the duration of PPE wearing, and past medical history of skin diseases. Due to the increased incidence of PPE-associated dermatoses among the medical staff, some countries have developed recommendations on the prevention and treatment of undesirable PPE-associated skin reactions in medical professionals. Current research are focused on developing special tools and devices that would serve as a protective barrier between the skin and PPE, ameliorating the damaging effect of the latter.

Conclusion. PPE-associated dermatoses are currently widespread among the medical workers, highlighting the need in novel materials for PPE manufacturing to minimise the risk of developing PPE-associated skin lesions.
Surgical risk assessment in Hiv-infected patients treated within the penitentiary system of Kemerovo region
Authors: Malashenko A. A. , Krasnov K. A. , Krasnov O. A.
Published: January 2022

Aim. To assess the surgical risk in HIV-infected patients who received the surgical treatment within the penitentiary system of Kemerovo Region.

Materials and Methods. We retrospectively analysed the physical status and the extent of surgical risk in 296 HIV-infected patients who underwent elective (n = 201) or emergency (n = 95) surgery in Hospital №1 (Kemerovo) from 2015 to 2018. Physical status was assessed according to American Society of Anesthesiologists (ASA) Physical Status Classification System. Surgical risk was scored according to Moscow Scientific Society of Anesthesiologists and Critical Care.

Results. The majority of patients had 3 (48.4 and 36.3% in emergency and elective patients, respectively) or 4a (30.5 and 45.8% in emergency and elective patients, respectively) stages of HIV infection. Opportunistic infections were diagnosed in 49.3% of patients and were always accompanied by superficial mycoses. Physical status of most patients (47.4% and 63.7% in emergency and elective patients, respectively) corresponded to ASA physical status class 3. Emergency patients mainly had surgical risk class 3 (n = 50, 52.6%) while elective patients often had surgical risk class 2 (n = 106, 52.7%). The prevalence of postoperative complications, most often impaired wound healing, was 9.8%.

Conclusion. More than 80% of HIV-infected patients who underwent surgical interventions within the penitentiary system of Kuzbass were at III or IV stages of HIV infection, entailing a high frequency of opportunistic diseases such as superficial mycoses and dictating the need to include antifungal treatment into the surgical treatment. Impaired wound healing was the most frequent postoperative complication.
Risk factors for death in patients with severe COVID-19 admitted to an intensive care unit
Authors: Osyaev N. Yu. , Ivannikova N. V. , Vavin G. V. , Moses V. G. , Gruzdeva O. V. , Kutikhin A. G.
Published: January 2022

Aim. Severe COVID-19 is accompanied by reduced blood oxygen saturation, systemic inflammatory response syndrome and multiple organ failure, all causing a significant deterioration of homeostasis associated with death. Here we aimed to study the risk factors for death in patients with severe COVID-19 who have been admitted to an intensive care unit.

Materials and Methods. The study included 144 consecutive patients with severe COVID-19 who have been admitted to an intensive care unit of Kuzbass Clinical Hospital from August to December 2020. Groups of survivors and non-survivors were equal in number (n = 72) and matched by gender (36 men and women) and age (median age 64 years, interquartile range 56-70 years in survivors and 58-69 years in non-survivors). Complete blood count, urinalysis, biochemical analysis, coagulation testing, and measurement of anti-SARS-CoV-2 IgM/IgG were carried out in all patients immediately upon the admission to intensive care unit.

Results. Risk factors for death in severe COVID-19 at the admission to intensive care unit were arterial hypertension, chronic heart failure, peripheral atherosclerosis, impaired renal homeostasis (reduced glomerular filtration rate, elevated serum creatinine and urea, proteinuria, hematuria), augmented fasting blood glucose and lactate, neutrophilia (in men), lymphopenia and increased neutrophil-to-lymphocyte ratio (in women), and decreased IgM/IgG to SARS-CoV-2 (in women).

Conclusion. We found both independent and gender-specific risk factors for death due to COVID-19.
Galectin-1 and Galectin-3 expression in colon cancer and its correlation with tumor invasion, differentiation, and metastatic spread
Authors: Kolobovnikova Yu. V. , Urazova O. I. , Poletika V. S. , Reyngardt G. V. , Romanova E. V. , Kurnosenko A. V. , Dmitrieva A. I. , Yankovich K. I. , Grishchenko M. Yu.
Published: January 2022

Aim. To study the expression of galectin-1 and galectin-3 in colon cancer and the levels of these proteins in the peripheral blood in relation to the differentiation, invasion, and metastatic dissemination.

Materials and Methods. We examined primary tumors and the corresponding peripheral blood samples from 81 patients with colon cancer. Control group consisted of 49 patients with colon adenoma and 17 healthy volunteers. Expression of galectin-1 and galectin-3 in colon tissue was determined by immunohistochemical staining, while their plasma level was measured by enzyme-linked immunosorbent assay. Tumor staging was performed in accordance with the TNM system (AJCC, 2009). Cell differentiation was defined according to the respective clinical guidelines (Russian Cancer Association, 2018).

Results. We detected an elevated expression of galectin-1 and galectin-3 in primary colon cancer as compared with colon adenoma and higher plasma levels of these proteins in colon cancer patients in comparison with healthy volunteers. High expression of tumor and plasma galectin-1 was associated with higher tumor stage (T3/T4) and the presence of local and distant metastases. Overexpression of galectin-3 in the primary tumor correlated with lower differentiation and lymph node metastasis.

Conclusion. Galectin-1 and galectin-3 are involved in colon cancer progression and might be used as predictors of an adverse outcome.
Prototyping neural networks to evaluate the risk of adverse cardiovascular outcomes in the population
Authors: Bogdanov L. A. , Komossky E. A. , Voronkova V. V. , Tolstosheev D. E. , Martsenyuk G. V. , Agienko A. S. , Indukaeva E. V. , Kutikhin A. G. , Tsygankova D. P.
Published: January 2022

Aim. To develop a neural network basis for the design of artificial intelligence software to predict adverse cardiovascular outcomes in the population.

Materials and Methods. Neural networks were designed using the database of 1,525 participants of PURE (Prospective Urban Rural Epidemiology Study), an international, multi-center, prospective study investigating disease risk factors in the urban and rural areas. As this study is still ongoing, we analysed only baseline data, therefore switching prognosis and diagnosis task. Because of its leading prevalence among other cardiovascular diseases, arterial hypertension was selected as an adverse outcome. Neural networks were designed employing STATISTICA Automated Neural Networks (SANN) software, manually selected, cross-validated, and transferred to the original graphical user interface software.

Results. Input risk factors were gender, age, place of residence, concomitant diseases (i.e., coronary artery disease, chronic heart failure, diabetes mellitus, chronic obstructive pulmonary disease, and asthma), active or passive smoking, regular use of medications, family history of arterial hypertension, coronary artery disease or stroke, heart rate, body mass index, fasting blood glucose and cholesterol, high- and low-density lipoprotein cholesterol, and serum creatinine levels. Our neural networks showed a moderate efficacy in the virtual diagnostics of arterial hypertension (84.5%, or 1,289 successfully predicted outcomes out of 1,525, area under the ROC curve = 0.88), with almost equal sensitivity (83.6%) and specificity (85.3%), and were successfully integrated into graphical user interface that is necessary for the development of the commercial prognostication software. Cross-validation of this neural network on bootstrapped samples of virtual patients demonstrated sensitivity of 82.7 – 84.7%, specificity of 84.5 – 87.3%, and area under the ROC curve of 0.88 – 0.89.

Conclusion. The artificial intelligence prognostication software to predict adverse cardiovascular outcomes in the population can be developed by a combination of automated neural network generation and analysis followed by manual selection, cross-validation, and integration into graphical user interface.
Insulin gene expression and functional activity of insulin signaling pathway in Alzheimer's disease
Authors: Gorina Y. V. , Khilazheva E. D. , Komleva Yu. K. , Lopatina O. L. , Salmina A. B.
Published: January 2022

Aim. To study the insulin (INS) gene expression, insulin and lactate levels, expression of Fe65 adapter protein, and level of oxidative DNA damage marker γH2AX in different brain areas in the experimental model of Alzheimer's disease.

Materials and Methods. Male, 4-month-old C57BL/6 mice received either intrahippocampal injection of β-amyloid (C57BL/6 + Aβ 1-42) or phosphate-buffered saline (C57BL/6 + PBS). Insulin (INS) gene expression in the hippocampus and amygdala was assessed by means of reverse transcription-polymerase chain reaction. Levels of lactate and insulin in different brain areas were measured by enzyme-linked immunosorbent assay. Expression of Fe65 adapter protein and γH2AX in the hippocampus was studied by immunofluorescence staining followed by confocal microscopy.

Results. We found an overexpression of the INS gene in the hippocampus and amygdala, an increase in lactate level in the hippocampus, and slightly increased insulin level in the amygdala of mice with Alzheimer's disease as compared with the control group. Neurodegeneration was accompanied by an elevated endothelial expression of Fe65 adapter protein (p= 0.04) and γH2AX in hippocampal neurons (p = 0.04).

Conclusion. Alzheimer's disease neurodegeneration is accompanied by a disrupted insulin signaling and impaired glucose metabolism in the hippocampus and amygdala. This further leads to a neuronal accumulation of γH2AX and impaired amyloid precursor protein proteolysis because of insulin inability to inhibit its interaction with the Fe65 adapter protein and to prevent formation and deposition of β-amyloid.
The impact of legionellosis into fatal outcomes of pneumonia in Irkutsk
Authors: Botvinkin A. D. , Svistunov V. V. , Sidorova E. A. , Makarova A. E. , Kravchenko N. A. , Stepanenko L. A. , Bayanova T. A. , Lemeshevskaya M. V. , Balandina T. P. , Gibteva O. S. , Andaev E. I. , Balakhonov S. V.
Published: January 2022

Aim. To study the diagnosis of legionellosis in patients who died because of pneumonia in Irkutsk (2016-2018).

Materials and Methods. We performed 65 autopsies of patients who died from pneumonia in Irkutsk (2016-2018), studied their case histories, and interrogated 510 tap water samples for Legionella pneumophila by means of inoculation and polymerase chain reaction.

Results. Among 65 fatal pneumonia outcomes registered in Irkutsk during 2016-2018, legionellosis has been confirmed in three cases (4.6%). Two of these patients were at the late stages of HIV infection while the third, 74-yearold, patient had multiple comorbid conditions. Nosocomial infection was suspected in one of these cases. None of these three patients left Irkutsk during the last month of their life. The assumed transmission factor was tap water, as Legionella pneumophila was found in tap water samples collected in 2013 and 2015.

Conclusion. Patients with severe pneumonia need screening for legionellosis to perform the correct treatment, particularly during COVID-19 pandemic.
Incidence of multiple sclerosis and prevalence of its risk factors in Russian Federation
Authors: Svetlichnaya A. V. , Vyazovichenko Yu. E. , Torchinskiy N. I. , Korshunov V. A.
Published: January 2022

Aim. To study the incidence and prevalence of multiple sclerosis risk factors in Russian Federation from 2009 to 2019.

Materials and Methods. We used official records of Ministry of Health of Russian Federation and conducted a survey of 50 patients with multiple sclerosis (16 men and 34 women) admitted to the Sechenov University Clinic of Neurological Disorders to determine subjective risk factors.

Results. Current incidence of multiple sclerosis in Russian Federation is 3.8 per 100,000 population, with a steady increase from 2009 to 2019. The highest and the lowest incidence values were registered in the Central Federal District (4.5 per 100,000 population) and Far Eastern Federal District (2.0 per 100,000 population). The most common subjective risk factors were female gender, past medical history of viral diseases, chronic bacterial infections, and emotional stress.

Conclusion. Incidence of multiple sclerosis in Russian Federation is currently rising that highlights the need in the improved therapeutic protocols.
Explainable Artificial Intelligence (XAI) for Population Health Management – An Appraisal
Authors: Naik Het , Goradia Priyanka , Desai Vomini , Desai Yukta , Iyyanki Muralikrishna
Published: January 2022

This study explores Explainable Artificial Intelligence (XAI) in general and then talked about its potential use for the India Healthcare system. It also demonstrated some XAI techniques on a diabetes dataset with an aim to show practical implementation and implore the readers to think about more application areas. However, there are certain limitations of the technology which are highlighted along with the future scope in the discussion.
Factors influencing distribution and habitat utilisation of Leptoptilos javanicus in and around Barandabhar Corridor Forest, Chitwan, Nepal
Authors:   Tribhuvan University, Wagle Yureshiya , Bhattarai Bishnu P. ,   Tribhuvan University, Adhikari Jagan N. ,   Tribhuvan University
Published: January 2022

The globally Vulnerable wetland-dependent bird species Leptoptilos javanicus was once thought to avoid farmlands, but recent studies in lowland Nepal showed that the species uses farmlands extensively for foraging and breeding. Identifying whether this preference of L. javanicus to these habitats is common throughout Nepal is essential to understanding the conservation needs of the species. This study aimed to explore the seasonal distribution and habitat utilisation by L. javanicus in and around the Barandabhar Corridor Forest by using 220 randomly selected squares within a 500 × 500 m2 grid. We visited centroids of each selected square to collect data on L. javanicus distribution, habitat types, and probable causes of disturbance in two seasons (rainy: August – September 2019 and winter: December – January 2019–2020). A total of 64 observations of L. javanicus (n = 29 in winter, n = 35 in rainy) were made. Leptoptilos javanicus were seen in more squares outside the Protected Area (65.2%) during the rainy season. Variables that negatively influenced L. javanicus sightings were distance to the road (few individuals seen close to the road), distance to the village (few individuals seen close to settlement), and areas under human disturbance (only few individuals seen in areas with more livestock and people) during both seasons. The farmlands around the Barandabhar Corridor Forest hosted many individuals of L. javanicus and are a new location in lowland Nepal with a resident population of this species. Past assumptions regarding L. javanicus conservation require revision, and including a focus on farmlands is an important requirement in Nepal's conservation planning.
In Silico Study of the Effectiveness of 16S rRNA Gene as a Universal Genetic Marker to Identify Closely Related Burkholderia Spp. in Panicle Blight of Rice
Authors: Mohamad Naim Nur Alifah Ilyana , Tajul Anuar Nabihah Raihanah , Ahmad Lyena Watty Zuraine , Kambol Roziah , Syed Mohamad Sharifah Aminah , Aris Farizan , Zakaria Nurul Aili , Mohamed Yunus Norfatimah
Published: January 2022

The 16S rRNA gene is a housekeeping genetic marker that is available in almost all bacterial species and it is used in bacterial phylogeny and taxonomy studies. In many studies, the 16S rRNA gene is used in identification of certain bacterial species. Being a less conserved genetic marker, certain studies found it is a useful tool to infer the genome-wide similarity levels among the closely related prokaryotic organisms. Thus, this study aimed to compare the variation in the 16S rRNA partial region of Burkholderia spp. that infect the panicle of rice from eight different geographical areas. 58 sequences with total of 688 base pairs (bp) of 16S rRNA gene in B. glumae and B. gladioli were retrieved from public database based on several countries namely United State, Panama, Ecuador, Thailand, China, India, Korea and Malaysia. Then, the data sequences were analysed and validated using MEGAX and ABGD software respectively. The result of phylogenetic tree confirmed that B. glumae and B. gladioli were species that present in the panicle blight of rice. However, Data Analysis in Molecular Biology and Evolution (DAMBE) and Automatic Barcode Gap Discovery (ABGD) software were not able to detect substitution saturation and divergence between B. glumae and B. gladioli respectively based on the 58 sequences of the 16S rRNA partial region. Hence, it proves that 16S rRNA gene is an ineffective genetic marker to be used to differentiate the closely related species of bacteria from similar genus.
Kinetics Studies of Metallic Ions Adsorption by Immobilised Chitosan
Authors: Pitchay Thanabalan , Jawad Ali H. , Johari Ili Syazana , Sabar Sumiyyah
Published: January 2022

Immobilised chitosan on glass plates was used as an adsorbent for metallic ions from aqueous solutions in a batch adsorption system. Experiments were carried out as a function of contact time and initial metallic ions concentration. The adsorption efficiency increased with increasing initial metallic ions concentration (5 – 20 mg L-1) and the observed trend was: Ag2+ > Cu2+ > Ni2+ > Fe3+ > Cd2+ > Zn2+. The experimental data were fitted to pseudo-first, pseudo-second-order, intra-particle, and liquid film diffusion kinetic models. The applicability of the pseudo-second-order kinetic model indicated that the adsorption behaviour was ascribed by chemisorption. Further data analysis by the diffusion kinetic models suggested that the metallic ions adsorption was controlled by more than one step; adsorption at the active sites, intra-particle, and liquid film diffusion.
Orientaciones para el cambio de los patios escolares como impulsores de la igualdad de género a través de la actividad física
Authors: Zapatero Ayuso Jorge Agustín , Ramírez Rico Elena , Rocu Gómez Patricia , Navajas Seco Rosaura
Published: January 2022

El patio es uno de los lugares donde más interacciones sociales se producen, contribuyendo a la construcción de género en la escuela. Este trabajo analiza la literatura previa para profundizar sobre cómo los estereotipos de género condicionan el acceso al ocio en el patio. El recreo continúa siendo un momento que transmite estereotipos de género. Las chicas (y algunas minorías de chicos) son menos activas y ven más limitadas sus oportunidades de ocio en el patio. El profesorado, la formación de grupos, los juegos simbólicos, la vestimenta o el lenguaje son agentes transmisores de estereotipos. Se concluye con orientaciones para promover la igualdad de género y el ocio activo categorizadas del siguiente modo: medidas físicas, como la división de zonas con fines diferentes claramente visibles; medidas sociales, como la concienciación de alumnado y profesorado sobre las desigualdades de género en el patio; y medidas organizativas, como establecer turnos de uso de materiales e infraestructuras.
Autorrepresentación de atletas españolas en Instagram: estudio de casos
Authors: Piedra Joaquin , López-Villar Cristina
Published: January 2022

Las redes sociales cada día tienen más peso en nuestra sociedad y las deportistas españolas están presentes en ellas. La literatura existente muestra el creciente interés del ámbito científico sobre las lógicas de las redes y la representación de las deportistas, aunque muy limitado en el caso de nuestro país. Por tanto, el objetivo de este artículo fue analizar la autorrepresentación de tres deportistas españolas famosas y de diferentes deportes. Para ello, se realizó un análisis de contenido de sus publicaciones en Instagram, entre febrero de 2020 y febrero de 2021. Los resultados han mostrado que cada deportista tiene un estilo diferente de autorrepresentación, existiendo también puntos en común. Las imágenes que reciben más likes no siguieron ningún patrón, pero en dos casos la centralidad del cuerpo fue clara. Se concluyó, tras el análisis y discusión, que las tres mantienen una imagen de feminidad socialmente aceptada, en la que en cada caso se presentaron elementos, incluida la publicidad, que contribuyeron a dicho ideal heteronormativo y propio de una sociedad androcéntrica. Además, sólo en un caso, se detectó una autorrepresentación alternativa a la tradicional de los medios de comunicación. Profundizar en la relación entre redes sociales y deporte es una línea de trabajo futuro de gran potencial, pues son cada vez más los y las deportistas, aficionados y medios de comunicación que hacen uso de ellos.
Experiencias de mujeres deportistas de alto nivel ante a la realidad androcéntrica del deporte
Authors: Martínez Abajo Judit , Lasarte Leonet Gema , Aristizabal Llorente Pilar , Vizcarra Morales Mª Teresa
Published: January 2022

A lo largo de la historia, la realidad androcéntrica ha ignorado e ignora a las mujeres deportistas en general y a las deportistas de alto nivel en particular. Esa praxis que invisibiliza a la mujer deportista en el mundo de la competición no va sola, se acompaña de sexismo. Hemos querido analizar cómo repercuten tanto el sexismo como el androcentrismo en la construcción identitaria de las mujeres deportistas de alto nivel. Se ha llevado a cabo un estudio de caso en el que participan 33 deportistas vascas. Se han realizado 19 entrevistas en profundidad y tres grupos de discusión. Se puede concluir que el deporte en la actualidad funciona como un mecanismo biopolítico de construcción de las identidades de género. Pero en la medida que las mujeres deportistas van ocupando los espacios anteriormente vetados para ellas, van convirtiendo en realidad el deporte femenino y originando voces críticas, que piden tanto la igualdad de oportunidades para los distintos géneros como la disolución en el deporte de fronteras entre los mismos.
The Effect of Perceived Overqualification on Job Crafting
Authors: Park YoungSeok , Shin YoungEun
Published: January 2022

This study focused on job crafting for employees to solve the problem when they have the misfit between self and their jobs. Specifically, the effects of perceived overqualification, which is a misfit between job requirements and ability of employee, on job crafting were examined, and the moderating effect of achievement goal orientation was tested in the relationship between the two variables. As a result of a survey of 341 workers, perceived overqualification had a significant positive effect on job crafting. The approach goal orientation, more specifically, the performance-approach goal orientation had a moderating effect in the relationship between perceived overqualification and job crafting. The higher the performance-approach goal orientation, the stronger the correlation between perceived overqualification and job crafting. These results suggest job crafting is a series of behaviors for increasing performance rather than mastering abilities. Based on these results, the research implications, limitations, and follow-up studies were discussed.
The effect of Coaching Leadership on Organizational Trust and Innovative Behavior: Moderated Mediation by Power Distance Orientation
Authors: Chung EunKyoung , Park SeonKyu
Published: January 2022

The purpose of this study is to reveal the effect of coaching leadership on organizational trust and innovative behavior depending on the level of power distance orientation. Specifically, the relationship between coaching leadership and innovative behavior was examined and the mediating effect of organizational trust was identified in the effect of coaching leadership on innovative behavior. In addition, this study examined a moderating effect of power distance orientation on the relationship between organizational trust and innovative behavior Finally, the relationship between coaching leadership and innovative behavior is verified by the moderated mediating effect of power distance orientation in the mediation of organizational trust. For this purpose, data from 697 Korean workers were collected through Embrain, an Internet survey company in Korea. According to the research, the relationship between coaching leadership and innovative behavior has been proven to have a partial mediating effect significantly by organizational trust. The moderating effect of the power distance orientation and the moderated mediating effect were also both significant. Employees with lower organizational turst and lower power distance orientation tended to innovate more than employees with higher power distance orientation, but the difference was found to have been decreased significantly at a higher level of organizational trust. Finally, we discussed practical implications, limitations, and future research.
Social Dominance Orientation and Job Performance
Authors: Yoo TaeYong , Lee HyunJun
Published: January 2022

Recently, as one of few personality traits which significantly predicts discrimination and prejudice against various social groups, the researches on the effect of social dominance orientation are substantially growing, however researches directly aimed at the effect of social dominance orientation on individual performance are still limited. In this research, from the interactionalistic approach of person-environment, based on social dominance theory and resource theory, we investigated the effect of social dominance orientation on the employee’s job performance(task performance and contextual performance), along with exploring the moderating effect of leader-member resource exchange domains(contribution exchange and affect exchange) and job meaning factor from psychological empowerment. Self-reported survey data were obtained from 345 employees from various organizations in Korea. The results showed that LMX contribution exchange buffered the negative impact of social dominance orientation on contextual performance. The interaction between social dominance orientation and LMX affect exchange affected task performance negatively, but job meaning significantly reduced the negative impact. Based on these results, we discussed implications and limitations of this study and directions for future research.
The effect of goal-orientation on observational learning within the context of comparison with a high-performing coworker
Authors: Yoo TaeYong , Choi HyoIm
Published: January 2022

Why some learn lessons from a high-performing coworker’s behavior and apply to themselves whilst others do not? The aim of the current research is to understand the characteristics of those who do learn lessons by observing high-performing coworker’s behaviors even though the interaction with them may be threatening. Specifically, we suggest that high-LGO(learning goal orientation) individuals and high-PPGO(performance prove goal orientation) individuals are observing high-performing coworker's behavior intention. Also, based on the motivated action theory, we argue that individuals with a different goal orientation set higher goal level with a different referenced goal level (i.e., self vs. other). The data from American full-time employees (n=221) has revealed that both LGO and PPGO had a positive relationship with observational learning. In addition, self-referenced goal level mediated the relationship between LGO and observational learning, while other-referenced goal level mediated the relationship between PPGO and observational learning. Based on the results, the implications of this study and the directions for future researches were discussed with limitations.
Studi Etnobotani Tumbuhan Obat Suku Anak Dalam di Desa Sungai Jernih Kecamatan Rupit Kabupaten Musi Rawas Utara Sumatera Selatan
Authors:   Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Sriwijaya, Sri Pujihastuti Laila , Tanzerina Nina , Aminasih Nita
Published: January 2022

Pemanfaatan tumbuhan sebagai obat tradisional telah banyak diketahui sejak lama oleh masyarakat terutama Suku Anak Dalam yang ada di Desa Sungai Jernih Kecamatan Rupit, Kabupaten Musi Rawas Utara Sumatera Selatan. Penelitian ini bertujuan untuk menginventarisasi jenis-jenis tumbuhan obat, mengetahui famili dan habitus, jenis-jenis penyakit, organ tumbuhan yang digunakan, cara pengolahan dan cara penggunaan tumbuhan yang digunakan oleh etnis Suku Anak Dalam sebagai obat tradisional untuk mengobati berbagai jenis penyakit. Metode yang dilakukan menggunakan metode survei deskriptif dengan melakukan wawancara kepada 3 orang narasumber yang merupakan pengobat tradisional (batra) untuk membantu proses pengumpulan data di lapangan. Hasil penelitian menunjukkan tumbuhan yang dijadikan sebagai obat oleh masyarakat Suku Anak Dalam didapatkan sebanyak 93 jenis tumbuhan dengan 48 famili dan famili terbesar adalah Fabaceae dan Piperaceae masing-masing (6,45%) dan mampu mengobati sebanyak 47 macam jenis penyakit dengan 116 ramuan obat. Habitus tumbuhan terbesar adalah perdu (32,25%) dan sebanyak (60,21%) tumbuhan obat tumbuh secara liar baik yang tumbuh liar didalam hutan dan tumbuh liar dipekarangan rumah. Bagian organ tumbuhan yang digunakan paling banyak adalah daun (59,13%), cara pengolahan terbesar yakni dengan cara direbus (67,74%) dan cara penggunaan terbesar adalah dengan diminum (61,29%).
La consolidación de la trayectoria coercitiva del régimen europeo de asilo hasta la pandemia
Authors:   Investigador sénior, CIDOB, Comte Emmanuel
Published: January 2022

Desde la perspectiva de la trayectoria política a largo plazo del régimen europeo de asilo, ¿cómo se han desarrollado las políticas de asilo en Europa durante la pandemia de la COVID-19? Cuando esta estalló, los estados miembros de la UE llevaban tres décadas intentando sin éxito resolver las deficiencias del Convenio de Dublín de 1990, las cuales persistieron tanto por la sobrecarga de los estados miembros de primera línea como por los esfuerzos por controlar los flujos secundarios de los solicitantes de asilo en la Unión. Así, la pandemia no ha supuesto al respecto ni un paréntesis ni un punto de inflexión, sino más bien ha generado una situación fluida que ha precipitado la retirada del Reino Unido y la consolidación de la tendencia coercitiva a largo plazo hacia los solicitantes de asilo, entre los estados miembros y en sus fronteras exteriores.