bluuebunny/crossref_metadata_2025 huggingface dataset:
The Emotional Backdrop of Legal Discourses in South China Sea Disputes
Authors:   Vendée Catholic University (ICES) (France), Pomès Eric , Coicaud Jean-Marc ,   Rutgers University, State University of New Jersey (USA)
Published: June 2021

The China Sea connects as many coastal states as it divides due to the economic and strategic challenges it represents. It also embodies an area of confrontations between the Great American and Chinese strategies. Identifying with precision the differences that arise requires an interest in the symbolic dimensions that surround them. This angle of analysis provides an opportunity to observe the functioning of international law and inevitably leads to a discussion of the emerging international order. The literature on the situation in the China Sea abounds. The paper’s singularity is to approach it under the prism of international law as revealing the psychology of an actor. To carry out this research, the authors use a pragmatic and critical approach to international law. The thesis defended shows that, contrary to a positivist and judicial approach to international law, elements exogenous to the law, the history, and the psychology of an actor, influence the interpretation of existing norms.
The Teacher and the Idea of Society 5.0 – Initial Diagnosis of the Problem
Authors:   Silesian University of Technology (Poland), Pituła Beata
Published: June 2021

The primary aim of this article is to present the results and research findings of a pilot study on teachers’ attitudes manifested toward the idea of society 5.0. The study is a part of one of the priority research areas of the Silesian University of Technology – Processes automation and Industry 4.0. in terms of the socio-cultural and methodological implications of Industry 4.0. Eighty-four teachers participated in the research and completed the questionnaire electronically. The research bores the characteristics of a preliminary diagnosis of the problem. Hence, the collected empirical material does not allow the formulation of methodologically valid conclusions. However, it may constitute a “voice in the discussion” on the preparation of teachers for the inevitable change of the role of the school and the teacher in the new society.
Color characteristics of the blazar S5 0716+714 under geometrical origin of the long-term variability
Authors:   Kazan (Volga Region) Federal University, Gorbachev M. A. ,   Crimean Astrophysical Observatory of RAS, Butuzova M. S. ,   Crimean Astrophysical Observatory of RAS, Nazarov S. V. ,   Crimean Astrophysical Observatory of RAS
Published: June 2021

The optical radiation of the blazar S5 0716+714 is formed within its ultrarelativistic jet in a compact region located near the true origin of the jet. Assuming that the variability is formed only by changing the relativistic radiation amplification coefficient (Doppler factor) for some part of the emitting region and that the spectrum of the emitting region, characterized by a power law at the observed frequencies, has a turn-over at lower frequencies, caused by synchrotron self-absorption, we analyze the archival data of the Crimean Astrophysical Observatory of B-, V-, R-, I-photometry of the blazar S5 0716+714 from 2002 to 2019. An explanation for the observed change in the color index during the blazar S5 0716+714 variability without changes in the physical parameters of the source was obtained.
Galactic bars: a look at the point of view of action variables
Authors:   Saint-Petersburg State University, Zozulia V. D.
Published: June 2021

We have translated the results of bar modeling in N-body simulations into the language of action variables JR, Lz and Jz. We used the AGAMA package and the formalism associated with the Steckel potential. Action variables were calculated in the changing non axisymmetric potential of the model at different moments of the bar evolution. We found that at the later stages of the bar evolution, the maximum values of JR are reached at its ends, after which, upon going to the disk, JR decreases monotonically. As for Jz, the maximum values of Jz actually outline the B/PS bulge, the thickest part of the bar. Such a behavior of the action variables can be used for tests to identify the features of the bar of our Galaxy based on GAIA data.
Method for determination of cluster radius from radial density profile
Authors:   Ural Federal University, Kulesh M. V. , Seleznev A. F. ,   Ural Federal University
Published: June 2021

We propose the numerical method for determining the radius of a star cluster using its radial surface density profile. The method realizes the algorithm of an eye estimate but minimizes a subjectivity; its result is in a good agreement with the eye estimate of the radius for the open cluster NGC 2516.
The precision of the orbit fitting for selected NEAs frompositional observations at the Terskol Observatory
Authors:   Tomsk State University, Galushina T. Yu. , Levkina P. A. ,   Tomsk State University,   Institute of Astronomy of the Russian Academy of Sciences, Letner O. N. ,   Tomsk State University
Published: June 2021

The paper deals with the results of asteroid observations in September 2020 with the Zeiss-2000 telescope of the Centre for collective use Terskol observatory . We considered their influence on the precision of the orbit fitting and the size of the initial confidence region. It is shown that in most cases the addition of the obtained observations reduces the value of the mean square error and the size of the confidence region.
Cyclicity of variations of the magnetic field of the eclipsing variable AM Leo
Authors:   Kourovka astronomical observatory of Ural Federal University, Gorda S. Yu.
Published: June 2021

Based on the 14-year photometric CCD monitoring of the contact eclipsing variable star AM Leo of type W UMa carried out author from 2007 to 2020 at the telescopes of the Kourovka observatory UrFU, the presence cyclic variations in brightness of the system with a period of 7.6±0.6 years, not associated with the phenomena of eclipses and tidal deformations of the components, as well as low-amplitude cyclic variations of the orbital period with the same value of the oscillation period, were found. It was concluded that the low-amplitule variations of the brightness and period of the system are due to the cyclic changes of the magnetic field of the components of the AM Leo, which manifests itself in a change in the average surface temperature of the overall system shell due to changes in the area of cold or hot spots on the surface of the components, as well as the influence of the Applegate effect on the system period.
Light curve feature extraction from astronomical source
Authors:   Lomonosov Moscow State University, Faculty of Space Research, Lavrukhina A. D. , Malanchev K. L. ,   Lomonosov Moscow State University, Sternberg astronomical institute,   Department of Astronomy, University of Illinois at Urbana-Champaign
Published: June 2021

Astronomy is entering the era of large surveys of the variable sky such as Zwicky Transient Facility and forthcoming Legacy Survey of Space and Time. These surveys are dedicated to observe the apparent celestial sphere in several days. The usage of an automatic extraction of light curve features is required to work effectively with such amount of data, especially in problems of classification and characterisation of variable sources. In this work, we present the new Python library for extraction of 25 light curve features of variable astronomic sources.
A technique for describing line profiles of the CO molecule using a multi-component radiation transfer model
Authors:   Astronomical Observatory of the Ural Federal University, Ladeyschikov D. A.
Published: June 2021

In this work, we investigated the features of the analysis of complex CO line profiles in giant molecular clouds (GMCs). A technique has been developed to use several emission lines of the CO molecule to build a model and determine GMCs physical parameters within the local thermodynamic equilibrium framework. The technique includes clumps extraction using the GAUSSCLUMP algorithm and constructing a multilayer radiation transfer model for clumps using optimization and Monte Carlo methods. The technique was applied to analyze largescale mapping of the S231-S235 star formation complex in four different CO lines.
X-ray emission fromHerbig stars
Authors:   Crimean Astrophysical Observatory RAS, Ryspaeva E. B.
Published: June 2021

The archived X-ray observations of 9 Ae/Be Herbig stars obtained on the XMM-Newton space observatory are analysed for checking the hypotheses of their X-rays formation. An analysis of the dependences of the X-ray radiation characteristics for Herbig stars on the parameters of the stars revealed a close relationship between the magnetic activity and the processes of generation of X-ray radiation from Herbig stars, as well as the possible presence of a non-thermal component of the X-ray spectra.
Study of the filament WB 673 in ammonia radiolines
Authors:   Institute of Astronomy of the Russian Academy of Sciences, Ryabukhina O. L. , Kirsanova M. S. ,   Institute of Astronomy of the Russian Academy of Sciences
Published: June 2021

We study the molecular filament WB 673 which is located at a distance of 1.8 kpc in the giant molecular cloud G174 + 2.5. Observations of ammonia radiolines NH3 (1,1), (2,2) and (3,3) were carried out in 2019 at the Effelsberg observatory (Germany). The parameters of the lines were determined, maps of the integrated intensities of ammonia in dense clumps WB 668, WB 673, S233-IR and G173.57+2.43 were obtained. The column density of ammonia and the kinetic temperature of the gas were obtained. An analysis of the hyperfine structure anomalies of the NH3 (1,1) lines was carried out.
Age estimation of young pairs of asteroids in close orbits: pair (87887) 2000 SS286 — (415992) 2002 AT49
Authors:   Ural Federal University, Safronova V. S. , Kuznetsov E. D. ,   Ural Federal University
Published: June 2021

The main ideas of the method for determining the age of young pairs of asteroids in close orbits based on the results of the analysis of the probabilistic evolution of orbits are presented. As an example, estimates of the age of the pair (87887) 2000 SS286 — (415992) 2002 AT49 were obtained, which range from 7.8 to 8.2 kyr.
Asma não controlada em crianças e adolescentes expostos aos agrotóxicos em região de intensa atividade do agronegócio
Authors: Rocha Cyndielle Barcelos da , Nascimento Alessandra Pinheiro Costa , Silva Ageo Mário Cândido da , Botelho Clóvis
Published: June 2021

Resumo: O objetivo deste estudo é analisar os fatores associados à asma não controlada em escolares expostos aos agrotóxicos em município de médio porte de Mato Grosso, Brasil. Estudo do tipo caso controle, realizado com escolares de 6 a 7 anos e 13 a 14 anos de Primavera do Leste, em 2016. Foram considerados casos, escolares que preencheram critérios para asma não controlada por meio de questões do International Study of Asthma and Allergies in Childhood (ISAAC), os controles foram selecionados a partir das mesmas escolas dos casos, após randomização, numa relação de 1:1. Para a coleta de dados, foram utilizados os questionários da Fase I e II do ISAAC e o questionário adicional para a exposição aos agrotóxicos. Realizaram-se a análise descritiva, bivariada e regressão logística das variáveis sociodemográficas e econômicas, individuais e ambientais. Foram selecionados 319 casos e 319 controles, totalizando em 638 participantes do estudo. No modelo final da regressão logística, as variáveis renda familiar maior que quatro salários mínimos (OR = 14,36; IC95%: 8,89-23,20), ter mãe com escolaridade até Ensino Médio incompleto (OR = 16,32; IC95%: 8,96-29,75), prematuridade (OR = 13,25; IC95%: 4,83-36,41) e baixo peso ao nascer (OR = 17,08; IC95%: 5,52-52,90) mantiveram-se associadas à asma não controlada. Das variáveis de exposição aos agrotóxicos, presença de pessoas no domicílio que trabalham na agricultura (OR = 5,91; IC95%: 2,11-16,53), residir próximo da atividade agrícola (OR = 3,98; IC95%: 1,47-11,76) e a pulverização aérea próxima ao domicílio (OR = 4,20; IC95%: 1,49-11,87) relacionaram-se ao desfecho. Neste estudo, os agrotóxicos e as condições sociodemográficas e de nascimento e infância mostraram-se relacionados à asma não controlada em escolares.
THE STRATEGY OF PHYSIOLOGICAL AROUSAL OF ATHLETES IN SPORTS COMPETITION BASED ON DRUG INTERVENTION
Authors: Chen Jiao , Li Hongtao
Published: June 2021

ABSTRACT Generally speaking, the physiological index of the human body is in a relatively stable state, which refers to the function of various organ systems with the characteristics of high-tide period, low-tide period and critical period. However, for competitive athletes, it is necessary to maintain physiological activation in both training and competition. In view of this, this study will analyze the physiological arousal degree of aspirin and acetaminophen in order to provide a reference for athletes to take analgesic drugs. In this study, the analytic hierarchy process (AHP), principal component analysis and factor analysis, were used to construct a scientific evaluation system of physiological arousal level, and the medication and non-medication status of 90 athletes were evaluated. The results showed that aspirin was better than acetaminophen in blood urea and serum creatine kinase, and the comprehensive score of some athletes was higher than 0.95. Aspirin is better in arousing athletes’ physiology. The research results will provide scientific guidance for athletes to take antipyretic and analgesic drugs.
ANALGESIC EFFECT OF ROPIVACAINE AFTER ARTHROSCOPIC RECONSTRUCTION OF THE LIGAMENT IN ATHLETES
Authors: Liu Junjie , Guo Mingang
Published: June 2021

ABSTRACT After arthroscopic ligament reconstruction, athletes still need to go through a postoperative rehabilitation training period and suffer the possible pain that can go from moderate to severe. Commonly used analgesic medications, ropivacaine and fentanyl have the effect of relieving athletes’ pain. To study the analgesic effect of ropivacaine on arthroscopic reconstruction of the knee ligament, the steps of reconstruction and pharmacology of ropivacaine were first introduced. Next, the analgesic effects of ropivacaine and fentanyl in 86 athletes were compared on muscle strength recovery, patient satisfaction, and pain score. The results showed that the satisfaction of patients with ropivacaine was 95.35%, and the incidence of postoperative adverse reactions was only 9.30%. These results indicate that ropivacaine has a better analgesic effect in arthroscopic reconstruction of the knee ligament in athletes, which is suitable for postoperative rehabilitation.
COMPARISON OF HIGH-LEVEL ATHLETE TRAINING BETWEEN CHINESE AND AMERICAN UNIVERSITIES BASED ON THE INTERNET OF THINGS
Authors: Zhu Xidong
Published: June 2021

ABSTRACT In order to improve the training quality of high-level athletes in Chinese and American universities, an athlete’s sports information transmission model is designed based on the Internet of Things (IoT). The communication protocol between Ayla module and the main motion control board, Ayla module and client APP or cloud platform, and APP and cloud platform in the system is designed in detail. For the Ayla module, the most important hardware part of the system, the internal composition and software design are described. In the mobile phone client part that is closely related to the user, the MVC architecture is adopted, the singleton and agent design patterns are utilized, and the functional design of each part is elaborated, including APP interface animation, data transmission format, network communication, and database storage. The research results show that the system of this study can handle most of the athlete training information, and the prediction accuracy exceeds the traditional algorithm. This research study is of great significance for improving the training efficiency of high-level athletes and further expanding the scope of application of the IoT.
As abordagens-metodológicas de ensino de língua estrangeira no aplicativo Duolingo
Authors: Sataka Mayara Mayumi , Rozenfeld Cibele Cecílio de Faria
Published: June 2021

RESUMO O campo de estudos da Educação Linguística e Linguística Aplicada tem se debruçado, frequentemente, sobre a temática das Tecnologias Digitais de Informação e Comunicação (TDIC) e dos processos de ensino/aprendizagem de Línguas Estrangeiras (LE). Diante desse contexto, neste trabalho tomamos como objeto de estudo o aplicativo Duolingo, uma plataforma disponibilizada gratuitamente para a aprendizagem de LE. Nosso escopo recai sobre o ensino de Espanhol como Língua Estrangeira (E/LE), na sua versão de aplicativo para Android. Nesse sentido, apresentamos um recorte dos resultados de uma pesquisa de mestrado (Sataka, 2019), que teve como um dos objetivos compreender a(s) abordagem-metodológica(s) de ensino de línguas que subjaz(em) no aplicativo Duolingo. O arcabouço teórico que nos fundamenta teoricamente são os trabalhos sobre as TDICs na Educação e aprendizagem móvel (Boll, Ramos & Real, 2018; entre outros) e as abordagens-metodológicas de ensino de línguas (Larsen-Freeman, 2000; entre outros). A metodologia adotada consiste em uma pesquisa de natureza qualitativa e partiu das experiências de uso do aplicativo pela própria pesquisadora. As análises demonstraram que são, essencialmente, duas abordagens-metodológicas predominantes no aplicativo, a saber, gramática-tradução e método audiolingual. Ainda assim, concluímos que não se trata apenas da aplicação de antigas perspectivas teórico-metodológicas em uma nova proposta de aprendizagem, pois, no Duolingo, desvelam-se aspectos sociais, culturais e psicocognitivos contemporâneos.
O gênero promocional forro de bandeja de fast-food: uma colônia de gêneros
Authors: Ribeiro Luiz Antônio , Maggi Andrea Cristina
Published: June 2021

RESUMO Este artigo pretende discutir sobre o gênero de discurso forro de bandeja de fast-food, buscando analisar como ele integra as práticas sociais, ao mesmo tempo em que é gerado e configurado por elas. Sua natureza é a pesquisa aplicada, cujo objetivo é a aplicação prática da ciência. Essa reflexão considerou o conceito swasiano de gêneros de discurso e o conceito bhatiano de colônia de gêneros. A colônia de gêneros é um agrupamento de gêneros que estabelecem entre si um conjunto de relações complexas dentro e através de diferentes domínios discursivos de acordo com o escopo comunicativo a que se propõem. Analisado sob o viés do discurso promocional, o gênero forro de bandeja de fast-food mescla em si outros gêneros que mantêm interface com este e com outros domínios discursivos dos quais se originam. Os resultados parecem confirmar a hipótese de que cada gênero mesclado no forro de bandeja de fast-food contribui para o alcance dos propósitos comunicativos de natureza promocional.
AS ESCOLAS PRIVADAS BILÍNGUES E A QUALIFICAÇÃO DOCENTE
Authors: Padinha Thais Arantes , Goia Marisol Rodriguez
Published: June 2021

Resumo Em meio às tendências da rede privada de ensino no Brasil de atender à demanda das elites, o artigo discute a oferta de bilinguismo na educação infantil, analisando a qualificação exigida dos professores à luz das discussões sobre a estratificação horizontal do sistema de ensino superior brasileiro e seus efeitos para os cursos de Pedagogia. Foram realizadas entrevistas com representantes de cinco estabelecimentos em bairros nobres da cidade do Rio de Janeiro. Titulações, comprovação de proficiência, fluência “nativa” e habilidades práticas são requisitos básicos da qualificação docente para atuar com crianças de 0 a 5 anos. Evidencia-se que a tendência ao bilinguismo nas escolas privadas agrava as desigualdades de oportunidades entre os docentes.
ARBITRAGEM EM NÚMEROS NAS CÂMARAS DE SANTA CATARINA
Authors: Moura Aline Beltrame de , Copetti Michele , Monteiro Gustavo Becker , Omizzolo Bettina Gomes , Blanco Juliana , Weingartner Israel
Published: June 2021

Resumo O objetivo deste artigo é coletar dados que demonstrem o atual cenário da utilização do instituto da arbitragem no estado de Santa Catarina com base em consultas sobre o número de procedimentos arbitrais administrados por câmaras de arbitragem locais. Desse modo, a partir do envio de formulários às instituições arbitrais catarinenses, foi possível quantificar os procedimentos administrados, as matérias comumente envolvidas nos litígios, analisar a atuação de advogados em arbitragens administradas em Santa Catarina, entre outros aspectos. De posse dos dados coletados e da aplicação do método dedutivo para análise dos resultados, concluiu-se que, muito embora as instituições catarinenses relatem elevada quantidade de arbitragens sendo administradas ou já concluídas, o que se verifica, em realidade, é o grande número de procedimentos concluídos por meio de acordos, e que, por isso, acabam mais se aproximando de técnicas de conciliação e mediação do que propriamente de arbitragens.
Optimizing the usage of pupillary based indicators for cognitive workload
Authors: Fehringer Benedict
Published: June 2021

The Index of Cognitive Activity (ICA) and its open-source alternative, the Index of Pupillary Activity (IPA), are pupillary-based indicators for cognitive workload and are independent of light changes. Both indicators were investigated regarding influences of cognitive demand, fatigue and inter-individual differences. In addition, the variability of pupil changes between both eyes (difference values) were compared with the usually calculated pupillary changes averaged over both eyes (mean values). Fifty-five participants performed a spatial thinking test, the R-Cube-Vis Test, with six distinct difficulty levels and a simple fixation task before and after the R-Cube-Vis Test. The distributions of the ICA and IPA were comparable. The ICA/IPA values were lower during the simple fixation tasks than during the cognitively demanding R-Cube-Vis Test. A fatigue effect was found only for the mean ICA values. The effects of both indicators were larger between difficulty levels of the test when inter-individual differences were controlled using z-standardization. The difference values seemed to control for fatigue and appeared to differentiate better between more demanding cognitive tasks than the mean values. The derived recommendations for the ICA/IPA values are beneficial to gain more insights in individual performance and behavior during, e.g., training and testing scenarios.
Questioning the Border in Yoko Tawada’s Poetics of Trans-Formation: Akzentfrei (2016) and Ein Balkonplatz für flüchtige Abende (2016)
Authors: Russo Eriberto
Published: June 2021

Yoko Tawada, an established author with a Japanese background, is one of the most important writers of contemporary Germany. Her personal experience as a migrant – the first and major border - has played a central role in her literary activity. Her literary production oscillates between two styles: narratives and essays, which make full use of both ordinary and surreal aspects. In other words her works start from a ritual aspect of ordinary life and create a new dimension, which can be identified as the dimension of the border. The border becomes, this way, the dialectic device, through which texts transform and translate themselves into the otherness. My paper aims to analyze the concept of border in Tawada’s poetics, with particular attention to the border as a liminal space, as it displays itself in her last works Akzentfrei (2016) and Ein Balkonplatz für flüchtige Abende (2016). In both works borders play a central role, as they transform themselves after flowing and being crossed by identitary suggestions. Akzentfrei is to be seen as an imaginary journey into the In-betweenness, during which, we, as readers, discover a new world made up of accents and translations, leading to the understanding of the condition of a writer, who writers in the ‘ravine of language’. Through an extraordinary desire to excavate the secrets of the words and the objects, which a writer on the threshold can encounter on his/her way, Tawada tells her reader about the way she tries to go beyond the border, which has actually turned out to be the writer herself. Ein Balkonplatz für flüchtige Abende, a poetic novel, can be understood as the synthesis of Tawada’s contact with the spaces of the borders. At the centre of the narration we find the figure of the Loreley, a siren, who loses her way and strands on the Elbe, in Hamburg. The siren and the other figures we encounter in the work do not possess fixed identities: in fact, they keep flowing through a translating otherness, which manifests itself through ordinary spaces (streets, canteens) hiding secrets and getting crossed by unfamiliar landscapes and worlds.
INFLUENCE OF ANTIBACTERIAL FACTORS ON THE MIXED CULTURE OF ESCHERISCHIA COLI AND STAPHYLOCOCCUS EPIDERMIDIS UNDER CONDITIONS OF INCREASED OSMOTIC PRESSURE
Authors:   Perm State University, Eltysheva I. V. , Zatvornitskiy L. E. ,   Perm State University, Maslennikova I. L. ,   Institute of Ecology and Genetics of Microorganisms
Published: June 2021

Commensal strains of the human intestine Escherichia coli K12 and of the human skin Staphylococcus epi-dermidis are often found in the same atypical biotopes, where they can act as infectious agents. The metabo-lism of bacteria changes in polymicrobial associations and in the presence of increased osmotic pressure in biotopes, associated with a number of pathological conditions that may affect their sensitivity to antibacterial factors of various nature. In this regard, the aim of the work was to study the effectiveness of chlorampheni-col, ceftriaxone, polyvalent pyobacteriophage and chlorhexidine on single and mixed cultures of opportunistic microorganisms E. coli K12 and S. epidermidis at a background of 2% NaCl. It was shown that the effect of ceftriaxone, a broad-spectrum antibiotic, and chloramphenicol, with antibacterial properties only against E. coli, were leveled under conditions of increased osmotic pressure at concentrations of 12-200 mg/l in a mixed culture. For E. coli K12, a decrease in the effectiveness of the bacteriophage at high osmotic pressure was noted, which is the opposite in effect towards S. epidermidis. As for chlorhexidine, its effect on E. coli K12 and S. epidermidis was enhanced in single and mixed cultures under conditions of 2% NaCl. In general, in most cases, an increase in the osmotic pressure of the medium acted as a synergist for inhibiting bacterial growth with antibiotics and bacteriostatic.
DYNAMICS OF THE CONTENT OF NITROGENOUS SUBSTANCES AND LIPIDS IN THE NEEDLES OF INTRODUCED SPECIES PICEA А. DIETR. IN THE TAIGA ZONE (KARELIA)
Authors:   Petrozavodsk State University, Kishchenko I. T.
Published: June 2021

Studies were conducted in the Botanical Garden of Petrozavodsk State University, located in the taiga zone. The objects were 1 aboriginal (Рicea fennica (Regel) Кom.) аnd 5 introduced (P. pungens Engelm. f. glauca Regel and f. viridis Regel, P. obovata Ledeb., P. glauca (Mill.) Britt., P. omorica (Pane) Purk., P. mariana Britt.). It is established that in the process of adaptation of introduced species Picea to low winter tempera-tures most of the involved proteins. Their number increases significantly during the transition from the period of active shoot growth to a period of deep rest have all studied species of Picea. The accumulation of proteins causes a decrease in the level of total free amino acids of most types of exotic species, while the local form of the amino acid content is maintained at a high level. In the needles of most of the studied species of Picea to the period of deep rest, the fraction of glutamic acid and albanina and increases the proportion of arginine and ethanolamine in the total amount of amino acids. The increase in the content of total lipids and phospholipids in the needles during the transition to a period of deep rest less significant than proteins. In the needles of na-tive species in comparison with the needles of exotic species total lipids actively used in the phase of inten-sive growth of shoots. Despite some differences, the introduced species Picea adapted to endure low tempera-tures using the same biochemical mechanisms as a local view. This indicates successful adaptation of the studied introduced species Picea to new conditions of existence.
APPLICATION OF ALPHA-FETOPROTEIN IN IMMUNOPHARMACOLOGY – BACKGROUND
Authors:   Institute of Ecology and Genetics of Microorganisms of the Ural Branch RAS, Shardina K. Yu. , Zamorina S. A. ,   Institute of Ecology and Genetics of Microorganisms of the Ural Branch RAS,   Perm State University, Raev M. B. ,   Institute of Ecology and Genetics of Microorganisms of the Ural Branch RAS,   Perm State University, Chereshnev V. A. ,   Institute of Ecology and Genetics of Microorganisms of the Ural Branch RAS,   Perm State University
Published: June 2021

The immunopharmacological potential of alpha-fetoprotein (AFP) is closely related to its ability to modulate the activity of cells of the immune system. Due to the immunomodulating properties, as well as the transport function - the transfer of low molecular weight substances, AFP is used in the treatment of a number of pathological conditions. The first attempts to use the therapeutic potential of AFP are associated with the use of extracts of embryonic tissues, with the development of technology, purified AFP from abortive material was used as a drug, and in some cases, recombinant forms of AFP were used. These drugs are intended primarily for the treatment of autoimmune as well as cancer. The review presents data on known variants of AFP dosage forms. In general, the study of the mechanisms of action of AFP at the level of the immune system is currently an urgent issue.
IMPACT OF WEATHER CONDITIONS ON VEGETATIVE PROPAGATION OF GLADIOLUS × HYBRIDUS HORT. IN PERM REGION
Authors:   Perm State University, Chertkova M. A.
Published: June 2021

Weather conditions have a significant impact on diameter of the corms formed from corms of II and III size and cormels. Corms formed from planting material of the II (average diametr 4.88±0.29 cm), III (average diametr 4.32±0.36 cm) size and cormels (average diametr 1.81±0.14 cm) in hot and dry 2016 year were significantly larger than in cold and rainy 2017 (average diametr respectively 3.57±0.33 cm, 2.78±0.27 cm и 1.40±0.07 cm) and 2018 (average diametr respectively 4.00±0.37 cm, 2.46±0.32 cm и 1.07±0.15 cm). Corms of I size are less affected by weather conditions. In Perm region it is optimal to use corms of I, II, and III size for planting. Cormels form corms of III and IV size, which bloom at the 2nd year. The propagation of gladiolus cultivars by cormels is promising in Perm region.
HEMATOLOGICAL PARAMETERS AND PARASITE FAUNA OF AMUR SLEEPER PERCCOTTUS GLENII IN A SINGLE-SPECIES ICHTHYOCENOSIS OF A SMALL URBAN RESVOIR
Authors:   Perm State University, Sheina T. A. , Kostitsyna N. V. ,   Perm State University, Baklanov M. A. ,   Perm State University
Published: June 2021

The article presents the results of hematological and parasitological studies of Amur sleeper Perccottus glenii of a small reservoir of artificial origin located in the vicinity of Perm. In this reservoir, Amur sleep-er is the only representative of the ichthyofauna. The collection of material was carried out in the spring-summer period of 2019. A total of 55 specimens of Amur sleeper were studied (30 specimens on May 8 and 25 specimens on July 12). Significant differences were found in the majority of quantitative indicators of fish blood cells in the spring and summer periods: in summer, the number of hematopoietic cells is higher (except for lymphocytes and monocytes), and in general, the content of mature leukocytes in the blood microliter in summer is lower. The parasite fauna of Amur sleeper in the studied reservoir is ex-tremely impoverished and is represented by the infusoria Trichodina nigra, cestode Nippotaenia mogurndae and nematodes, the latter were not recorded in Amur sleeper in this reservoir previously. The relationship between hematological parameters and the extent of parasite invasion was revealed: in more infected fish the number of immature erythrocytes, protoleukocytes, as well as neutrophils and eosinophils is significantly higher. The large numbers of Amur sleeper in the studied reservoir, the absence of devel-opmental anomalies in all the studied specimens, and the low proportion of fish with blood cell patholo-gies indicate the relative well-being of the studied part of the Amur sleeper population.
INFLUENCE OF HERACLEUM SOSNOWSKYI MANDEN. ON BIODIVERSITY OF VASCULAR PLANTS OF THE PROTECTED AREA «LIPOVAYA GORA» (PERM)
Authors:   Perm State University, Tiunov D. N. , Efimik E. G. ,   Perm State University
Published: June 2021

The problem of invasion of Sosnowsky hogweed (Heracleum sosnowskyi Manden.) In the Lipovaya Gora SPNA in Perm is considered. A map of distribution of hogweed cenopopulations in the protected area is presented. The results of the influence of the invasion of Sosnovsky hogweed on the biodiversity of vascu-lar plants of some plant communities are presented. It was revealed that the invasion of hogweed into phytocenoses of the Lipovaya Gora protected area leads to a decrease in the biodiversity of vascular plants by about 26.4% (up to 12 plant species). The ways of introduction of cow parsnip into the communities of the protected area are considered. High seed productivity, high projective cover, reaching in some cases 100%, high phytomass, the presence of dormant seeds, rapid development in spring, and high anthropo-genic load on the territory determine the rapid spread of H. sosnowskyi.
ON THE PROBLEM OF SEDIMENT TRANSPORT ASSESSMENT
Authors:   Perm State University, Lepikhin Anatoly P. ,   Russian Research Institute for the Integrated Use and Protection of Water Resources (Kama Branch),   Mining Institute of the Ural Branch of the Russian Academy of Sciences, Wozniak Anna A. ,   Perm State University,   Russian Research Institute for the Integrated Use and Protection of Water Resources (Kama Branch),   Mining Institute of the Ural Branch of the Russian Academy of Sciences
Published: June 2021

The paper discusses the problem of high errors in the design ratios proposed for assessing sediment transport in natural watercourses. The question is why numerous empirical design ratios obtained and successfully used for some watercourses can give an error of 1000% when applied to other rivers. Calculation formulas worked out on hydraulic trays and channels are found to be inappropriate for specific rivers and natural channels. The problem is caused by the complexity of the natural watercourses geometry and the heterogeneity of the bottom sediment composition. Two approaches that are currently used in assessing the transporting capacity of river flows are studied in the paper. They were laid down in river hydraulics as early as the second half of the 18th century in the works by A. Chesi and P. Dubois. The conditions and possibilities of using both methods are considered and theoretically proven in the paper. The approach developed by P. Dubois is distinguished by a detailed study of the influence of individual factors based on numerous experimental models, the construction of fairly rigorous physical models on this basis, the complication of design ratios, the inclusion of new additional parameters. A. Chesi offered the construction of a maximally simplified initial physical model, with the calibration parameters established for specific conditions on the basis of field observations or qualitative estimates, and therefore being less accurate but more stable. It is shown that despite the scientific attractiveness of the approach to constructing and using more complex calculation models containing new additional parameters, the inclusion of additional parameters entails the inclusion of additional errors associated with the estimation of these parameters. The effectiveness of both approaches is proved; the application of one or the other approach is determined by the conditions and nature of the tasks to be solved, as well as the volume and accuracy of the initial data.
INFLUENCE OF ANTHROPOGENIC AND NATURAL FACTORS ON THE CONTENT OF POLLUTANT METALS IN MEDICINAL PLANTS OF THE MIDDLE PRE-URAL REGION (ZAKURYE ISLAND IN CHUSOVOY)
Authors:   Perm State University, Solovyev Alexander D. , Shcherban Marina G. ,   Perm State University, Plotnikova Maria D. ,   Perm State University
Published: June 2021

According to the estimates of the World Health Organization, the share of medications based on medicinal plant materials is increasing from year to year. Along with industrial drugs, the population widely uses medicinal plants harvested on their own. However, medicinal plants growing in unfavorable environmental conditions can cause serious harm to health. Thus, it is necessary not only to control raw materials but also to study the areas where harvested medicinal plants grow, which in most cases are located in the immediate vicinity of industrial facilities. The purpose of this work was a comprehensive study of the ecological state of Zakurye Island in the town of Chusovoy and its plant communities. When planning the research work, the study area was zoned in accordance with the distance from the alleged source of pollution. In the process of work, we used standard methods of preparation and drying of medicinal plant materials, sampling of soil and water. Chemical analysis was carried out with the use of generally accepted and approved methods. A conclusion is made about a significant degree of pollution with pollutant metals of the surface and deep layers of the Chusovaya River, as well as of soil and medicinal plants near Zakurye Island. Most likely, environmental pollution is associated with poorly maintained dumps of blast-furnace slag from the Chusovoy Metallurgical Plant, located along the river bank.
SHORT TERM MICROBIAL COLONIZATION OF REPTILE ROADKILL
Authors: Hull Zeb C. , Unger Shem D.
Published: June 2021

Little is known about how microbes such as bacteria and fungi in the environment tempo­rally colonize common roadkill reptile carcasses (turtles and snakes). We opportunistically collected and deployed a variety of reptile carcasses often found deceased near roads, including an Eastern Ratsnake (Pantherophis alleghaniensis), an Eastern Box Turtle (Terrapene carolina), and a Snapping Turtle (Chelydra serpentina). We sampled bacteria communities of these carcasses daily for five con­secutive days. We enumerated the number of colony-forming units (CFUs) and characterized microbial distinct colonies using morphology and identification of dominant colonies using 16S rRNA sequencing across carcasses. Several ecologically relevant bacterial phyla were successfully identified colonizing and dominating carcasses differentially, including members of Actinobacteria, Firmicutes, and Proteo­bacteria. We observed higher bacterial colonization (CFUs) for both terrestrial and aquatic turtles, T. carolina and C. serpentina, compared to P. alleghaniensis. This study provides baseline data on the temporal microbiology of deceased reptiles found on roads in the piedmont of North Carolina.
Inference in Multiple Linear Regression Model with Generalized Secant Hyperbolic Distribution Errors
Authors: Burbano Moreno Álvaro Alexander , Melo-Martinez Oscar Orlando , Qamarul Islam M
Published: June 2021

We study multiple linear regression model under non-normally distributed random error by considering the family of generalized secant hyperbolic distributions. We derive the estimators of model parameters by using
modified maximum likelihood methodology and explore the properties of the modified maximum likelihood estimators so obtained. We show that the proposed estimators are more efficient and robust than the commonly used least square estimators. We also develop the relevant test of hypothesis procedures and compared the performance of such tests vis-a-vis the classical tests that are based upon the least square approach.
BRICS’ Contribution to the Global Transition to Sustainable Consumption and Production Patterns
Authors:   Centre for International Institutions Research, Russian Presidential Academy of National Economy and Public Administration, Sakharov Andrey , Andronova Inna ,   Peoplesʼ Friendship University of Russia (RUDN University)
Published: June 2021

The rationalization of production and consumption patterns lies at the core of sustainable development as it determines the level of anthropogenic impact on the environment, which is ultimately the subject of all international climate arrangements. This topic broadly encompasses not only sustainable development goal (SDG) 12, but also certain aspects of SDGs 7 and 11. The role of BRICS countries (Brazil, Russia, India, China and South Africa) in promoting the concept of sustainability globally is determined by their place among the leading producers and consumers of natural resources and emitters of pollutants, as well as the parties to major global agreements in this area. This article focuses on the institutional contribution of the BRICS agenda to the international community’s efforts to achieve the SDG targets related to the rationalization of resource production and consumption. In addition, because the socio-economic crisis of 2020 caused by the COVID-19 pandemic is seen as one of the factors impeding the implementation of the goals, the article also highlights the impact of COVID-19 and the crisis response of BRICS governments on long-term strategic planning for sustainable development.
THE ROLE OF INVESTMENT PROMOTION POLICY IN ATTRACTING FOREIGN DIRECT INVESTMENT: THE CASE OF SLOVAKIA
Authors:   University of Economics in Bratislava, Aneta Hintošová , Terézia Barlašová ,   University of Economics in Bratislava
Published: June 2021

Foreign direct investment (FDI) is generally considered as an important driver of economic growth and employment opportunities. In particular, countries in transition are adopting their investment promotion policies to attract FDI and direct it to the required sectors and regions. Public financial support in the form of investment incentives is used as one of the direct tools of investment promotion policy. However, this financial support is only considered effective in attracting FDI if the country attains the minimum threshold of quality of the business environment. The aim of the present study is to evaluate development of investment promotion policy, especially the provision of financial and fiscal investment incentives, as well as the level of economic freedom with regard to attracting FDI in Slovakia. The findings indicate that the preference of particular forms of investment incentives by the Slovak government has changed over time. The results of the regression analysis further show that while financial incentives have a positive statistically significant effect on FDI inflows, in the case of fiscal stimuli this effect is surprisingly negative. Based on our results, the overall level of economic freedom seems to not have a statistically significant effect on attracting FDI in Slovakia. The study contributes to the literature by providing a rationale for investment promotion policy reform and by offering some implications for governments seeking to attract targeted FDI.
GOOD LOCAL GOVERNANCE IN VIETNAM – BASED ON THE VIETNAM PUBLIC ADMINISTRATION PERFORMANCE INDEX IN RECENT YEARS
Authors:   Academy of Politics Region IV (belonging to Ho Chi Minh National Political Academy), Can Tho City, Vietnam, Trong Binh Nguyen
Published: June 2021

Currently, public governance theory and "good governance" have a profound and positive influence on the government reform process in many countries around the world today. In essence, good governance is the set of principles and criteria on social management to maximize public interests as well as promote and ensure the harmonious and sustainable development of a country. It can be said that good governance is both the ideal state and the goal that government reform in countries is aiming for, and the guiding principles for the design and operation of the state apparatus, government or system. In recent years, reform of government as well as reform of local government, according to good governance theory in Vietnam, has achieved many outstanding results. This is evident in the improvement in the indicators of provincial governance and public administration (Provincial Governance and Public Administration Performance Index (hereinafter referred to as PAPI)) in Vietnam over the years. Based on the survey results of PAPI in recent years, the article analyzes the good governance level of the local government of Vietnam, offers comments and assessments and proposes solutions on how to increase and strengthen the reform of local government in Vietnam according to good governance theory.
Fallopian Tube Single Cell Dissociation Protocol v1
Authors: Ulrich Nicole , Shen Yu-Chi , Hammoud Sue
Published: June 2021

This protocol describes the single cell dissociation of cells from fallopian tubes. The single cell dissociation protocol for myometrial cells can be found here.
Bacterial abundance from grass litter - Flow cytometry v1
Authors: not provided cweihe
Published: June 2021

This protocol is used to get the abundance of bacteria via flow cytometry from ground, decomposing grass leaf litter.
Study Design(Part 3 of Safety and Efficacy of Imatinib for Preserving Beta-Cell Function in New-onset Type 1 Diabetes Mellitus) v1
Authors: not provided Stephen.Gitelman , A. Bluestone Jeffrey
Published: June 2021

This is Part 3 of "Safety and Efficacy of Imatinib for Preserving Beta-Cell Function in New-Onset Type 1 Diabetes Mellitus". This clinical study is supported by JDRF. The aim of the collection is to determine whether imatinib will slow the progression of the autoimmune destruction of ß cells and lead to the preservation of C-peptide secretion in T1DM and to assess Diabetes-related objectives and safety of Imatinib in new-onset type 1 diabetes mellitus".
Adverse Events (Part 8 of Safety and Efficacy of Imatinib for Preserving Beta-Cell Function in New-onset Type 1 Diabetes Mellitus) v1
Authors: not provided Stephen.Gitelman , A. Bluestone Jeffrey
Published: June 2021

This is Part 8 of "Safety and Efficacy of Imatinib for Preserving Beta-Cell Function in New-Onset Type 1 Diabetes Mellitus". This clinical study is supported by JDRF. The aim of the collection is to determine whether imatinib will slow the progression of the autoimmune destruction of ß cells and lead to the preservation of C-peptide secretion in T1DM and to assess Diabetes-related objectives and safety of Imatinib in new-onset type 1 diabetes mellitus".
Access to Source Data/Documents (Part 10 of Safety and Efficacy of Imatinib for Preserving Beta-Cell Function in New-onset Type 1 Diabetes Mellitus) v1
Authors: not provided Stephen.Gitelman , A. Bluestone Jeffrey
Published: June 2021

This is Part 10 of "Safety and Efficacy of Imatinib for Preserving Beta-Cell Function in New-Onset Type 1 Diabetes Mellitus". This clinical study is supported by JDRF. The aim of the collection is to determine whether imatinib will slow the progression of the autoimmune destruction of ß cells and lead to the preservation of C-peptide secretion in T1DM and to assess Diabetes-related objectives and safety of Imatinib in new-onset type 1 diabetes mellitus".
Procedures for Performing the Mixed-Meal Tolerance Test (Appendix 2 of "Safety and Efficacy of Imatinib for Preserving Beta-Cell Function in New-onset Type 1 Diabetes Mellitus") v1
Authors: not provided Stephen.Gitelman , A. Bluestone Jeffrey
Published: June 2021

This is Appendix 2 of "Safety and Efficacy of Imatinib for Preserving Beta-Cell Function in New-Onset Type 1 Diabetes Mellitus". This clinical study is supported by JDRF. The aim of the collection is to determine whether imatinib will slow the progression of the autoimmune destruction of ß cells and lead to the preservation of C-peptide secretion in T1DM and to assess Diabetes-related objectives and safety of Imatinib in participants with new-onset type 1 diabetes mellitus".