bluuebunny/crossref_metadata_2025 huggingface dataset:
Metabolic characteristics and prognostic differentiation of aggressive lymphoma using one-month post-CAR-T FDG PET/CT
Authors: Breen William G. , Hathcock Matthew A. , Young Jason R. , Kowalchuk Roman O. , Bansal Radhika , Khurana Arushi , Bennani N. Nora , Paludo Jonas , Villasboas Bisneto Jose C. , Wang Yucai , Ansell Stephen M. , Peterson Jennifer L. , Johnston Patrick B. , Lester Scott C. , Lin Yi
Published: March 2022

Background

F-18 fluorodeoxyglucose positron emission tomography computed tomography (PET/CT) is used to assess response of non-Hodgkin lymphoma (NHL) to chimeric antigen receptor T cell (CAR-T) therapy. We sought to describe metabolic and volumetric PET prognostic factors at one month post-CAR-T and identify which patients with partial response (PR) or stable disease (SD) are most likely to subsequently achieve complete response (CR), and which will develop progressive disease (PD) and death.

Methods

Sixty-nine patients with NHL received axicabtagene ciloleucel CAR-T therapy. One-month post-CAR-T infusion and PET/CT scans were segmented with a fixed absolute SUV maximum (SUVMax) threshold of 2.5 using a semiautomated workflow with manual modification to exclude physiologic uptake as needed. Metabolic tumor volume (MTV), total lesion glycolysis (TLG), SUVMax, and other lesion characteristics were calculated and associated with risk of PD and death.

Results

Patients with total MTV > 180 cc, presence of bone or parenchymal disease, SUVMax > 10, single lesion TLG > 245 g, or > 2 total lesions had increased risk of death. Patients with total MTV > 55 cc, total TLG > 250 cc, SUV Max > 10, or > 2 total lesions had increased risk of PD. For the subset of 28 patients with PR/SD, higher SUVMax was associated with increased risk of subsequent PD and death. While 86% of patients who had SUVMax ≥ 10 eventually had PD (HR 3.63, 1.13–11.66, p = 0.03), only 36% of those with SUVMax < 10 had PD.

Conclusions

Higher SUVMax at one month post-CAR-T is associated with higher risk of PD and death. SUVMax ≥ 10 may be useful in guiding early salvage treatment decisions in patients with SD/PR at one month.
Management of severe neonatal respiratory distress due to vertical transmission of severe acute respiratory syndrome coronavirus 2: a case report
Authors: Verheijen Anne C. , Janssen Eva E. R. , van der Putten Mayke E. , van Horck Marieke W. P. , van Well Gijs T. J. , Van Loo Inge H. M. , Hütten Matthias C. , Van Mechelen Karen
Published: March 2022

Background

Neonates with severe acute respiratory syndrome coronavirus 2 infection are usually asymptomatic or have mild to moderate symptoms. Acute respiratory distress syndrome due to severe acute respiratory syndrome coronavirus 2 with respiratory insufficiency is rare. Therefore, information about the best intensive care strategy for neonates requiring mechanical ventilation is lacking. We report a neonatal case of severe acute respiratory distress syndrome, probably due to vertical transmission of severe acute respiratory syndrome coronavirus 2, complicated by Staphylococcus aureus sepsis. We aim to inform pediatric providers on the clinical course and acute management considerations in coronavirus disease-related neonatal acute respiratory distress syndrome.

Case presentation

A late preterm (gestational age 36 0/7 weeks) Caucasian girl was born from a severe acute respiratory syndrome coronavirus 2-positive mother and tested positive for severe acute respiratory syndrome coronavirus 2 at 19 hours after birth. She developed acute respiratory distress syndrome requiring intensive care admission and mechanical ventilation. The clinical course was complicated by S. aureus pneumonia and bacteremia. Multimodal management included well-established interventions for respiratory distress syndrome such as surfactant therapy, high-frequency oscillatory ventilation, and inhaled nitric oxide, combined with therapies extrapolated from adult care for severe acute respiratory syndrome coronavirus 2 patients such as dexamethasone, coronavirus disease 2019-specific immunoglobins, and prophylactic low-molecular-weight heparin. The neonate was successfully weaned from the ventilator and improved clinically.

Conclusion

This case shows a rare but serious neonatal severe acute respiratory syndrome coronavirus 2 infection, leading to severe acute respiratory distress syndrome. Because of limited therapy guidelines for neonates, we suggest multimodal management with awareness of the possibility of S. aureus coinfection, to treat this age group successful.
Creating an Agricultural World Order: Regional Plant Protection Problems and International Phytopathology, 1878–1939
Authors: CASTONGUAY STÉPHANE
Published: March 2022

Beginning in 1878 with the International Phylloxera Convention of Berne, international conventions have sought to relieve national agricultural industries from two specific burdens. First, by defining phytosanitary practices to be enforced by national plant protection services, these conventions attempted to prevent the introduction of plant diseases and pests into national territories from which they were previously absent. Second, by standardizing these practices—especially through the design of a unique certificate of inspection—the conventions attempted to eliminate barriers such as quarantines affecting international agricultural trade. The succession of phytopathological conventions seemed to epitomize the coalescence of an international community against agricultural pests. What actually coalesced was bio-geopolitics wherein plant pathologists and economic entomologists from North America and the British Empire questioned the so-called internationality of the environmental and economic specificities of continental European agriculture, embodied in "international" conventions. Although an international phenomenon, the dissemination of agricultural pests provided opportunities for cooperation on a strictly regional albeit transnational basis that pitted bio-geopolitical spaces against each other. This article retraces the formation of these spaces by analyzing the deliberations of committees and congresses that gathered to define an international agricultural order based on the means to prevent the spread of plant disease and pests.
Από την αντίληψη στην έκφραση
Authors: Πίπη Φίλια
Published: March 2022

Από πού ξεκινά ο αναγνώστης του Merleau-Ponty (1908-1961), αν θέλει να βάλει σε ένα πλαίσιο φαινομενολογίας και οντολογίας, όσα του κέντρισαν το ενδιαφέρον στα κείμενα του φιλοσόφου; Σε ένα έργο που, ενώ στο σύνολό του, μοιάζει να παραμένει εστιασμένο στην έννοια της αντίληψης, στην πορεία αποδεικνύεται πως αυτή ήταν μόνο ο πυρήνας που τροφοδοτεί μια φιλοσοφική διαδρομή που στρέφεται στον άνθρωπο, ο οποίος αναρωτιέται διαρκώς, που δεν εφησυχάζει. Ο κόσμος, στη μερλωποντιανή φιλοσοφία, το πεδίο της αντίληψης και της δράσης μας, αποτελεί τον ορατό και αισθητό ορίζοντα για το σώμα μας. Ένα σώμα το οποίο υπάρχει επίσης ως ορατό και αισθητό για τους άλλους. Η αντίληψη για τον Merleau-Ponty ορίζεται ως μια σωματική διαδικασία η οποία δεν είναι απλώς μια βιολογική διεργασία που συνδέεται με την όραση, ούτε αποτελεί μόνο απόδειξη της πνευματικής μας φύσης, της νόησής μας. Ο Merleau-Ponty μας καλεί να προσεγγίσουμε την αντίληψη ως χίασμα, δηλαδή ως την αμφίδρομη σχέση εξωτερικότητας και εσωτερικότητας, της ορατής μας φύσης και της ικανότητάς μας να κάνουμε δικό μας το ορατό. Η αντίληψη είναι ενέργεια: μια κίνηση με ροπή προς τον κόσμο. Στην εργασία αυτή θέτω την έκφραση ως την συμπληρωματική (πίσω) όψη της αντίληψης και προχωρώ προς μια φιλοσοφία του αντιληπτού κόσμου, έχοντας ως σημείο αναφοράς την τέχνη. Διότι η τέχνη δεν μπορεί παρά να αφορά στο πραγματικό, δεν μπορεί παρά να μιλά για τη σχέση μας με τον κόσμο. Η αντίληψη, η αίσθηση της όρασης και της αφής -όλοι τρόποι του ειδέναι-, δείχνουν τον δρόμο για να περάσουμε από την επιφάνεια στο βάθος, να ξεπεράσουμε το ορατό και να φτάσουμε στην άλλη όψη του. Τις διαστάσεις του ορατού, τις εναλλαγές του, τις μεταμορφώσεις του, τις μετατοπίσεις του, την απόσταση που μεσολαβεί μέχρι την αόρατη όψη του τις εντοπίζουμε μέσα στον χωροχρόνο. Και κάθε νέα αναφορά δύναται να περικλείει τις ίδιες πλευρές του ορατού ιδωμένες αλλιώς. Ο φιλόσοφος ξεκινά από την εμπειρία και το σώμα μας, και προοδευτικά μας οδηγεί στη σάρκα, στη γλώσσα και την ελευθερία. Αυτή η διαδρομή έχει δώσει τις κατευθυντήριες γραμμές της εργασίας. Ο άνθρωπος-καλλιτέχνης θα αποδείξει πώς η εμπειρία αποτελεί την πηγή της προσωπικής μας γνώσης, αλλά και πώς από την εμπειρία περνάμε στη γνώση της αντίληψης και από εκεί στις σκέψεις, το σώμα μου, το οποίο περικλείει βιώματα και νοήματα, ενώ ταυτόχρονα περιβάλλεται από τον κόσμο, και αποτελεί μέρος αυτού.
Επιτελική λειτουργικότητα σε δίγλωσσα παιδιά με ειδική γλωσσική διαταραχή
Authors: Τσινταβή Μαρία
Published: March 2022

Η γλώσσα αποτελεί μια μορφή επικοινωνίας και ένα σύστημα με συγκεκριμένα χαρακτηριστικά. Η ανάπτυξη της γλώσσας γίνεται με έναν φυσικό τρόπο στα τυπικά αναπτυσσόμενα παιδιά, σε άλλα παιδιά παρουσιάζει ελλείμματα. Η καθυστέρηση στη γλωσσική ανάπτυξη ή τα ελλείμματα όσον αφορά τη γλωσσική ανάπτυξη απασχολούν συχνά τους ειδικούς, όμως δεν υφίσταται πάντα απόλυτη συμφωνία ως προς τα κριτήρια που χρησιμοποιούνται για τον εντοπισμό και την κατάταξη των γλωσσικών διαταραχών στα παιδιά. Ο όρος Αναπτυξιακή Γλωσσική Διαταραχή (ΑΓΔ) αναφέρεται στις δυσκολίες που παρατηρούνται στην ανάπτυξη της γλώσσας και επηρεάζουν την ικανότητα επικοινωνίας, τη μάθηση και την καθημερινή λειτουργικότητα του ατόμου και δεν αποκλείει τη συνύπαρξη με άλλες νευροαναπτυξιακές διαταραχές, όπως η Διαταραχή Ελλειμματικής Προσοχής-Υπερκινητικότητα (ΔΕΠ-Υ). Επίσης έχει διαπιστωθεί ότι υπάρχει ένα κοινό πεδίο ελλειμμάτων μεταξύ της Αναπτυξιακής Γλωσσικής Διαταραχής και της ΔΕΠ-Υ, το οποίο αφορά σε ένα σύνολο αλληλοσυσχετιζόμενων δεξιοτήτων υπεύθυνων για την προσανατολισμένη σε ένα στόχο συμπεριφορά, καθώς και την ενεργό επίλυση προβλημάτων που ονομάζεται επιτελική λειτουργικότητα. Η διγλωσσία σχετίζεται συχνά με προηγμένες επιδόσεις στον τομέα της επιτελικής λειτουργικότητας, επομένως η μελέτη δίγλωσσων ΤΑ παιδιών και δίγλωσσων παιδιών με ΑΓΔ μπορεί να συμβάλλει στον τομέα αυτό. Στην παρούσα έρευνα συμμετείχαν συνολικά 50 παιδιά, μονόγλωσσα και δίγλωσσα με ΑΓΔ και μονόγλωσσα και δίγλωσσα τυπικά αναπτυσσόμενα (ΤΑ). Στους μετέχοντες χορηγήθηκαν δοκιμασίες νοημοσύνης, γλωσσικής ανάπτυξης επιτελικής λειτουργικότητας. Σύμφωνα με τα αποτελέσματα της παρούσας έρευνας, τα παιδιά με ΑΓΔ μονόγλωσσα και δίγλωσσα παρουσιάζουν χαμηλότερες επιδόσεις στη γλωσσική ευφράδεια, τη μετατόπιση προσοχής σε λεκτικά και μη λεκτικά ερεθίσματα, στη λεκτική αναστολή, τον σχεδιασμό, την ευφράδεια σχεδιασμού, την παρατεταμένη οπτική προσοχή, τη λήψη αποφάσεων με ρίσκο, την ευελιξία και τον συναισθηματικό έλεγχο. Επίσης, τα παιδιά με ΑΓΔ μονόγλωσσα και δίγλωσσα παρουσιάζουν χαμηλότερες επιδόσεις από τα ΤΑ μονόγλωσσα παιδιά στην κινητική αναστολή. Τα δίγλωσσα παιδιά με ΑΓΔ παρουσιάζουν χαμηλότερες επιδόσεις από τα ΤΑ παιδιά στην καθυστέρηση επιβράβευσης και τον ανασταλτικό έλεγχο. Επίσης τα μονόγλωσσα και δίγλωσσα παιδιά με ΑΓΔ παρουσιάζουν περισσότερα συμπτώματα ΔΕΠ-Υ σε σύγκριση με τα ΤΑ μονόγλωσσα και δίγλωσσα παιδιά. Η ΑΓΔ είναι πιθανό σε κάποιες περιπτώσεις να αποτελεί δευτερογενή συνέπεια της ΔΕΠ-Υ. Τα παιδιά με ΑΓΔ σε ορισμένες περιπτώσεις τουλάχιστον χρήζουν όχι μόνο λογοθεραπείας, αλλά και παρέμβασης στον τομέα της επιτελικής λειτουργικότητας.
Η φαρμακογονιδιωματική στο πλαίσιο της σύγχρονης βιοηθικής
Authors: Κορδώνης Θωμάς
Published: March 2022

Η φαρμακογονιδιωματική, ως η μελέτη των γενετικών πολυμορφισμών που επηρεάζουν τηνανταπόκριση ενός ασθενούς στο φάρμακο, είναι μια νέα σχετικά μέθοδος, που υπόσχεται ναπραγματοποιήσει το όνειρο του κάθε γιατρού για αποτελεσματικά φάρμακα χωρίς παρενέργειες. Γιανα επιτευχθεί όμως αυτό, θα πρέπει να γίνουν απαραίτητα εξετάσεις που αφορούν το γονιδίωμα καινα αξιοποιηθεί ένας μεγάλος όγκος δεδομένων, χρησιμοποιώντας τη σύγχρονη τεχνολογία. Ηδιαχείριση μιας τόσο μεγάλης ποσότητας ευαίσθητων προσωπικών δεδομένων, δημιουργεί πολλάερωτηματικά, κυρίως ως προς τη δυνατότητα να προστατευθεί το απόρρητο των ασθενών. Τοαπόρρητο, στο νέο πλαίσιο που δημιουργείται, αφενός μεν από την ανάγκη προστασίας τωνγονιδιωματικών δεδομένων, εξαιτίας του κινδύνου γενετικού στιγματισμού, αφετέρου δε από τηνανάγκη για την, όσο το δυνατό, ελεύθερη κυκλοφορία των γενετικών δεδομένων, ώστε ναμπορέσει η φαρμακογονιδιωματική να υλοποιήσει τους στόχους της, αντιμετωπίζεται μεαντιφατικούς, πολλές φορές, τρόπους. Τα γενετικά δεδομένα επίσης και οι εξειδικευμένες γνώσειςπου χρειάζονται για την προσπέλαση της πολυπλοκότητάς τους, δημιουργούν καινούργια διλήμματασχετικά με την ενημέρωση του ασθενούς κατά το στάδιο της συναίνεσής του, λόγω της μεγάληςασάφειας των αποτελεσμάτων που μπορεί να προκύψουν. Η κοινοκτημοσύνη που διακρίνει ταγενετικά δεδομένα, δημιουργεί το εύλογο ερώτημα, εάν η ατομική συγκατάθεση είναι αρκετή, ώστενα μην προσβληθεί η αυτονομία και όλων όσοι επηρεάζονται από αυτές τις εξετάσεις, χωρίς ναέχουν συναινέσει. Οι εταιρείες που ειδικεύονται στις γενετικές εξετάσεις, εκμεταλλευόμενες ίσως τηπολυδιαφημιζόμενη δυναμική των γενετικών εξετάσεων, απευθύνουν γενετικά τεστ απευθείαςστους καταναλωτές, με κίνδυνο παρερμηνείας των αποτελεσμάτων. Τέλος, τα στοχευμένααποτελεσματικά και στερούμενα ιδιαίτερων παρενεργειών φάρμακα, μπορούν να βελτιώσουν τιςγνωστικές λειτουργίες, με αποτέλεσμα την επίταση των γνωσιακών δεξιοτήτων και των ανισοτήτων.Ολοκληρώνοντας, επιχειρείται μια γενική αποτίμηση των βασικών διλλημάτων και θέσεων.
Spectral analysis and preconditioned iterative solvers for large structured linear systems
Authors: Μπαρακίτης Νικόλαος
Published: March 2022

Στην παρούσα διδακτορική διατριβή εξετάζεται η αριθμητική επίλυση για τρεις κατηγορίες προβλημάτων. Για τα προβλήματα αυτά, προτείνονται νέες τεχνικές επίλυσης μαζί με την θεωρητική τους ανάλυση και την αριθμητική τους επιβεβαίωση μέσω αριθμητικών πειραμάτων. Οι δύο πρώτες κατηγορίες είναι από το ερευνητικό πεδίο της αριθμητικής γραμμικής άλγεβρας και αφορούν την φασματική ανάλυση με εφαρμογές στην προρρύθμιση μεθόδων υποχώρων Krylov, των συντελεστών πινάκων, μεγάλων δομημένων γραμμικών συστημάτων. Η τρίτη κατηγορία είναι από το πεδίο των υπολογιστικών οικονομικών και αφορά το πρόβλημα της αποτίμησης ενός Αμερικανικού δικαιώματος (American put option).Στην πρώτη κατηγορία προβλημάτων εξετάζεται η ασυμπτωτική φασματική κατανομή μεγάλων πινάκων που προκύπτουν ως συναρτήσεις πινάκων Toeplitz. Συγκεκριμένα χαρακτηρίζεται αναλυτικά η συνάρτηση που περιγράφει την κατανομή των ιδιοτιμών. Λαμβάνοντας υπόψη την συνάρτηση αυτή προτείνονται κυκλοειδείς (circulant) προρρυθμιστές και αποδεικνύεται αναλυτικά η κατανομή των ιδιοτιμών των προρρυθμισμένων πινάκων. Όλα τα θεωρητικά αποτελέσματα επιβεβαιώνονται αριθμητικά.Η δεύτερη κατηγορία αφορά την θεωρητική και αριθμητική διερεύνηση κατάλληλων προρρυθμιστών, βασισμένων στο φασματικό σύμβολο, συντελεστών πινάκων που παράγονται από την διακριτοποίηση κλασματικών διαφορικών εξισώσεων (Fractional Differential Equations). Πέρα από την θεωρητική ανάλυση γίνεται και αριθμητική σύγκριση μεταξύ των προτεινόμενων προρρυθμιστών με τις υπάρχουσες τεχνικές επίλυσης. Τα αριθμητικά πειράματα δείχνουν η μέθοδος να είναι της ίδιας δυναμικής με τις υπάρχουσες αποδοτικότερες μεθόδους της διεθνούς βιβλιογραφίας αλλά να υπερτερεί εμφανώς στην πιο ενδιαφέρουσα από πλευράς εφαρμογών περίπτωση όπου η χωρική μεταβλητή είναι δυο διαστάσεων. Για την αποτίμηση του Αμερικανικού δικαιώματος χρησιμοποιούμε την τεχνική του δυναμικού προγραμματισμού κατάλληλα τροποοποιημένη για το συγκεκριμένο πρόβλημα. Χρησιμοποιώντας γνωστά χαρακτηριστικά της βέλτιστης συνάρτησης αποτίμησης του δικαιώματος, αποδεικνύεται θεωρητικά και επιβεβαιώνεται αριθμητικά ότι ο προτεινόμενος επαναληπτικός αλγόριθμος επιτυγχάνει μια αύξουσα ακολουθία συναρτήσεων αποτίμησης και εντέλει συγκλίνει με τετραγωνική τάξη στην βέλτιστη λύση. Αριθμητικά πειράματα δείχνουν την αποδοτικότητα της μεθόδου.
SOS-SDP: An Exact Solver for Minimum Sum-of-Squares Clustering
Authors: Piccialli Veronica , Sudoso Antonio M. , Wiegele Angelika
Published: March 2022

The minimum sum-of-squares clustering problem (MSSC) consists of partitioning n observations into k clusters in order to minimize the sum of squared distances from the points to the centroid of their cluster. In this paper, we propose an exact algorithm for the MSSC problem based on the branch-and-bound technique. The lower bound is computed by using a cutting-plane procedure in which valid inequalities are iteratively added to the Peng–Wei semidefinite programming (SDP) relaxation. The upper bound is computed with the constrained version of k-means in which the initial centroids are extracted from the solution of the SDP relaxation. In the branch-and-bound procedure, we incorporate instance-level must-link and cannot-link constraints to express knowledge about which data points should or should not be grouped together. We manage to reduce the size of the problem at each level, preserving the structure of the SDP problem itself. To the best of our knowledge, the obtained results show that the approach allows us to successfully solve, for the first time, real-world instances up to 4,000 data points.
Beam preserving and a low loss asymmetric pump and signal fiber combiner
Authors: lai W. J. , Cheran K.
Published: March 2022

We detailed the design and fabrication of a beam quality preserving and low insertion loss asymmetric (6 + 1)x1 pump and signal fiber combiner. Transmission efficiency of the beam combiner with different structure parameters such as taper ratios, taper lengths, etc are analyzed using the beam propagation method numerically. We experimentally demonstrated and investigated three design parameters and fabrication methods, including chemical wet etching, pre-tapering of fibers, and thermally expanding the core of bundle. Negligible beam quality factor Mx,y2 degradation of 0.05 / 0.02 and low insertion loss of 0.02 dB for pump and 0.16 dB for signal ports respectively were achieved.
Perspectivas intergeneracionales del cuerpo: estudio de casos
Authors: Burbano Chamorro Mario Andrés , Jiménez Ramos Andrés Mateo
Published: March 2022

El presente artículo es el resultado de la investigación denominada Reconocimiento del cuerpo en niños, jóvenes y adultos, que fue realizada con la población del Colegio Sagrado Corazón de Jesús Hermanas Bethlemitas en la ciudad de San Juan de Pasto. Esta población de estudio se clasificó de la siguiente manera: niños y niñas de grado transición y primero de primaria; adolescentes mujeres y hombres de grados décimo y once en básica media; y adultos de género femenino y masculino, los padres de familia de los escolares. Este proceso investigativo se desarrolló a partir de una metodología de carácter cualitativo y crítico, que permitió identificar, reconocer y configurar, por medio de los relatos escritos y las representaciones gráficas realizadas por la población de estudio, los significados del cuerpo en cada una de las etapas generacionales. Como resultado de la investigación, se logró establecer unas categorías que llevaron a configurar las diferentes concepciones del cuerpo: 1) corporeidad, 2) percepción del cuerpo, 3) sensaciones del cuerpo, 4) subjetividades del cuerpo e 5) intersubjetividades del cuerpo.
Aprender jugando con el relato ficcional infantil televisivo (Pakapaka)
Authors: Sabich María Agustina
Published: March 2022

En Argentina, la promulgación de la Ley de Servicios de Comunicación Audiovisual 26.522 de 2009 permite, entre otras cuestiones, la creación de Pakapaka, el primer canal público y federal dirigido a niños y niñas del país y de Latinoamérica. Con una programación que recupera contenidos del nivel inicial y primario, la señal surge bajo la responsabilidad del Ministerio de Educación de la Nación, motivo por el cual es posible identificar la estrecha relación que el canal tiene con la educación formal. Es por ello que el artículo explora las características de dos series audiovisuales especializadas en el tratamiento de la divulgación histórica y científica (La asombrosa excursión de Zamba y Vuelta por el universo). A partir de la identificación de diferentes escenografías multimediáticas, la investigación advierte que el relato ficcional televisivo establece diálogos con el discurso pedagógico, al mismo tiempo que pretende situar al espectador en una geografía local y regional.
Study trends on Resilience of Nursing Students -Focusing on nursing journals published in South Korea-
Authors: Kang Se-Won
Published: March 2022

This study is a literature review to understand the trends in the nursing students’ resilience published in nursing journals in South Korea. Among the papers published in nursing journals in South Korea, the research papers included “resilience” and “nursing students.”

As a result of the search, 40 papers suitable for literature review, which included three experimental studies and 37 descriptive studies, were selected for relational and factor analysis. The most frequently used variables along with resilience were self-esteem, self-leadership, depression, and emotional intelligence. In the future, intervention studies to strengthen the resilience of nursing students should be conducted.
Global Assets Mitigate Global Inflation
Authors: Bechtel Gordon
Published: March 2022

This article finds that 26 global assets mitigate global inflation. Fractional polynomial regressions return sizable goodness-of-fit R2s for these assets, along with high mitigating Pearson correlations between these assets and global inflation.  It is hoped that future fractional polynomial regressions will reveal other global assets that also mitigate global inflation. In view of Russia's invasion of the Ukraine, which preempted American President Biden's State of the Union address (Aljazeera, March 1 2022), and the trade war between the United States and China, the United Nations has now stepped in to protect it's member states from the interest-rate and inflationarity effects wrought by these three super powers.
Educational Management Decentralisation and Its Effect on Teacher Outputs: A Case of Ghanaian Basic Schools
Authors: Kyeremeh Alex , Kor Jacob Aaworb-nang Maabobr
Published: March 2022

Although touted as having impacts on educational performance in some countries not much attention has been given to investigating the relationship between decentralisation of educational management and the teacher outcomes in the Ghanaian context. The study thus sought to investigate the effect of decentralised systems on teacher motivation in Ghanaian basic public schools, to determine the effect of decentralised systems on quality teacher in Ghanaian basic public schools, and to investigate the effect of decentralised systems on Teacher discipline in Ghanaian basic public schools. A concurrent mixed design was employed in this study, however only quantitative findings are reported. A multistage random sampling technique was used to select 408 public and private schools from nine regions. Primary data based on a Cross-sectional survey making use of a survey questionnaire. Multiple Linear Regression analysis was employed for analysis. Results from Multiple Regression analysis reveal adequacy of the models of the study (R2 > 0.5). It was found that the District Education Oversight Committees roles in Personnel management, Organization of Instruction, had significant effect on teacher outputs including teacher motivation, teacher discipline, quality of teaching, and opportunities to learn. It was recommended that various Assemblies take the work of DEOC seriously and make resources available for their effective role in the management of Basic School to ensure effective implementation of decentralisation at the local level.
Die Re-Regulierung der Schlachthofarbeit in der Corona-Krise
Authors: Sebastian Marcel , Seeliger Martin
Published: March 2022

Die prekären Arbeits- und Beschäftigungsbedingungen in der Fleischindustrie sind seit geraumer Zeit Gegenstand von Regulierungsversuchen. Eine dreifache Krise – der europäischen Integration, der Arbeitsbeziehungen und der Naturverhältnisse – zog in der Vergangenheit jedoch keine substanzielle Regulierung nach sich. Unser Artikel zeigt, dass die pandemiebedingte Ausweitung der Konsequenzen auf Betroffene außerhalb der Fleischindustrie (etwa Anrainer:innen von Schlachthöfen) die Relevanz und den Handlungsdruck erheblich erhöht hat. Auch die symbolische Relevanz des Themas stieg im Zuge der Corona-Krise, weil die Regulierungen im Zusammenhang mit der Pandemiebekämpfung der Bundesregierung insgesamt gedeutet wurden. Unsere These lautet, dass sich die bemerkenswerte Geschwindigkeit der Re-Regulierung nur auf Basis der vorgängigen, dreifachen Krisendynamik der Fleischproduktion erklären lässt. Die Analyse des Policy-Wandels hat ergeben, dass die Debatte um Arbeit und Beschäftigung in der Fleischindustrie bereits seit 2007 geführt wird. Zögerliche Regulierungsversuche sahen zwar bereits 2014 einen branchenweiten Mindestlohn vor, der jedoch großflächig unterwandert wurde. Ob die neuen Regulierungen der Bundesregierung dies nun verhindern können, indem sie Leiharbeit und Werkverträge schrittweise verboten, bleibt abzuwarten.
Increased anxiety symptoms in pediatric type 1 diabetes during the acute phase of COVID-19 lockdown
Authors: Wade Caroline , Burton Elvin Thomaseo , Akinseye Leah , Nelson Grace , Smith-Young Jamila , Kim Ahlee
Published: March 2022

Objectives

The prevalence of mental health issues has increased at an alarming rate during the COVID-19 pandemic. Furthermore, an exacerbated psychosocial burden in populations with chronic disease is observed. This cross-sectional study evaluated the psychosocial factors of pediatric type 1 diabetes (T1D) during the COVID-19 pandemic.

Methods

During April 2020, 15 min phone interviews were performed for pediatric T1D group (n=100) and healthy comparison group (n=93) to assess psychosocial functioning during the acute lockdown phase of the pandemic. The patient health questionnaire-4 was utilized to assess anxiety and depressive symptoms. An additional questionnaire to assess specific concerns related to T1D and COVID-19 was administered to the T1D group to explore potential causes for increased psychosocial burden.

Results

T1D was associated with a five-times higher risk of anxiety symptoms. Increased anxiety symptoms in T1D group appear to be, at least in part, due to fear of higher risk of severe COVID-19 infection and uncertainty regarding access to diabetes supplies.

Conclusions

This study provides a snapshot of mental well-being in a diverse population of patients with T1D in the acute phase of a crisis and underscores the need for timely, accurate medical information and distribution of medical resources for pediatric T1D population.
Kreditgenossenschaften: Marktstruktur, Wettbewerb und Verhalten. Das Beispiel Paraguay
Authors: Schneider Andreas
Published: March 2022

Konzentrations- und Wettbewerbsmaße im Finanzsektor sind wichtig, um die öffentliche Politik zu orientieren. Genossenschaften, insbesondere im Kontext kleiner Entwicklungsländer, werden in der Wirtschaftsliteratur jedoch weitgehend ignoriert. Die empirische Analyse ist aufgrund der Datenverfügbarkeit deskriptiv und analysiert den Kreditmarkt großer Kreditgenossenschaften. Wir nutzen hierfür eine gepaarte Stichprobe, ausgewählt nach dem Konzentrationsprinzip, für die wir statische Konzentrationsmaße berechnen. Trotz der nicht repräsentativen Datenlage sind die Ergebnisse indikativ und bieten einen ersten Ausgangspunkt für Institutionen und Genossenschaften. Die Ergebnisse zeigen, dass die Kreditvergabe innerhalb des Genossenschaftssystems im Allgemeinen stark konzentriert ist und der Kreditmarkt praktisch in den Händen von zwei Genossenschaften liegt. Die Beteiligung kleiner Genossenschaften ist auf einen unbedeutenden Wert gesunken. Es scheint, dass die Marktkonzentration mit einer kontinuierlichen internen Migration zusammenhängt. Der Kreditmarkt großer Finanzgenossenschaften ist insgesamt nicht konzentriert, die meisten Kreditmodalitäten sind jedoch stark konzentriert, einige sind wettbewerbsfähig, andere nicht. Es gibt keine Hinweise auf einen Marktmissbrauch der drei größten Kreditgenossenschaften.
INVESTMENT INCENTIVES IN THE ENVIRONMENT OF THE CZECH REPUBLIC
Authors: Blaschke Petr
Published: March 2022

Investment incentives were originally created particularly to support the inflow of foreign capital into transforming economies. Today, they are also available in the developed countries of Western Europe, where they no longer fulfil their primary function but have become a standard and popular economic policy tool allowing the government to emphasise its impact on the country’s positive economic development (e.g., falling unemployment and reductions in unemployment benefits or recovery of public finance). Like any comprehensive system, the system of investment incentives has its supporters and opponents who cannot agree on their justification. The question is, whether they are efficient from the point of view of the government, as their provider. This is even more prevalent if the given investment was realised without investment support. Using the data of investment incentives provided by CzechInvest and selected macroeconomic indicators (Czech Statistical Office), as well as regression analysis of time series dependences, the aim of this paper is to verify the impact of investment supported by incentives (independent variables) on the macroeconomic climate of the Czech Republic (dependent variables) from 1998 to 2019. Based on the research findings, investment incentives cannot be described as an effective economic policy tool that clearly leads to the regions’ economic development. They contribute to an inflow of investments into (not only) structurally problematic regions (i.e., with higher unemployment or a lower economic level), but the positive impact of these investments on the macroeconomic climate is statistically negligible – not only at the regional level (NUTS 3), but also at the level of the whole economy (NUTS 1). In addition, the question remains as to whether or not the supported investments in the given region would have been implemented without the possibility of using incentives.
FINANCIAL CAPABILITY AS A FUNCTION OF FINANCIAL LITERACY, FINANCIAL ADVICE, AND FINANCIAL SATISFACTION
Authors: Ajaz Khan Khurram , Çera Gentjan , Pinto Alves Sandra Raquel
Published: March 2022

There is no substantial evidence that exists in the literature to establish the link between financial advice and financial capability fully establishes, even though ‘getting help’ is identified as an important aspect of financial capability. This study sets out to fulfil a couple of objectives. Its primary goal is to investigate the effects that a combination of financial literacy elements (financial attitude, financial knowledge, and financial behaviour), financial advice as well as financial satisfaction have on individuals’ financial capability, and secondly, to test and prescribe the improved scale of financial capability measurement. This research has been administered in Spain at an individual level. Hierarchical regression method along with Z-test were used. Regressions’ outcomes reveal that financial constructs positively impact the individuals’ financial capability. From the viewpoint of policymakers, it is vital to fully comprehend the significant factors influencing financial capability to plan better strategies to empower the citizens with adequate skills, abilities, and behaviour so to succeed in dealing with financial matters in daily basis. The originality and value added to the present study is two-fold. Firstly, it comprehensively examines the wide-ranging financial indicators seen as critical in determining financial capability, which remain yet not quite covered in other studies. Second, both indicators used to measure the financial capability revealed no substantial differences, therefore an improved composite scale is prescribed as useful in measuring financial capability in future research.
Religious Spaces, Urban Poverty, and Interfaith Relations in India
Authors: Sen Atreyee
Published: March 2022

The phenomenal rise of Hindu nationalism, and the implementation of a series of anti-minority decrees, has raised national and international concerns about the nature and culture of interfaith relations in contemporary India. While Hindu religious identities become increasingly politicized and integrated into nationalist propaganda, some ordinary Indians continue to defy absolute separation between communities. This essay suggests that urban poverty often becomes a context for entangled humanity across lines of faith, as the poor informally use their sacred spaces as arenas for retaining and reviving old and new forms of interreligious coexistence, mutual assistance, and reverence.
Bollywood’s Majoritarian Politics and the Independent Alternative
Authors: Devasundaram Ashvin Immanuel
Published: March 2022

India’s mainstream film industry has increasingly fallen under the influence of the Hindu nationalist ruling party and its agenda. But a thriving, multilingual independent sector is producing creative counternarratives.
Numerical Simulation Approach to Investigate the Effects of External Modifications in Reducing Aerodynamic Drag on Passenger Vehicles
Authors: Sadat Mostofa , Albab Nayef , Chowdhury Faria , Khan Mohammad Muhshin Aziz
Published: March 2022

This study used a numerical simulation approach to examine the effects of external modifications in reducing aerodynamic drag on passenger vehicles. During the simulation, modifications included reducing mirror size by replacing the side mirrors with cameras and covering the wheel area. The resulting changes in drag force for different combinations of modifications were compared with a conventional baseline model to determine the most aerodynamic configuration. The study found that side view cameras reduced drag forces by almost 2.6% due to their smaller frontal areas and improvement in the overall aerodynamics of the vehicle. Besides, an increase in wheel coverage decreased the drag causing up to 2.7% of drag force reduction for a wheel with an 87% coverage area. This is because of the reduction in wake formation caused by the wheel rims. Finally, using a combination of smaller cameras and wheels with larger coverage areas resulted in a maximum drag reduction of about 4.3%.
Wanita dalam Chanoyu pada Novel “The Life of an Amarous Man” Karya Ihara Saikaku (Kajian Sastra dan Budaya Jepang )
Authors: Karyati Alo
Published: March 2022

This study examines the role of women in chanoyu or the Japanese tea ceremony contained in the novel "The Life An Amarous Man" by Ihara Saikaku. This novel tells how the role of women (maids) in entertaining guests, making tea and attracting guests to come to the "tea house" or tea house. Chanoyu, in this novel, takes place in a tea house where the servants are a woman (maid). Chanoyu is one of the Japanese tea drinking cultures that is still preserved. Japan is rich in various traditional cultures still practised today, one of which is the chanoyu culture. Chanoyu is a literary activity in culture. So that chanoyu is very closely related to literature because, in the Chanoyu process, there are noble values, such as Japanese ritual activities, which are very sacred and have stages as elements in the Japanese teachings of patience and tenacity well as never giving up. These noble values ​​are part of literature. The formulation of the problem in this study relates to the role of women as maids in the tea house, and the position of the tea house is identical to chanoyu.
Ameloblastoma uniquístico: reporte de caso en una niña de 9 años
Authors: Balmaceda Rivera Paula , Utria Acevedo Iliany , López Aparicio Erich , Harris Ricardo Jonathan
Published: March 2022

El ameloblastoma uniquístico es un tumor odontogénico benigno, que representa menos de un tercio de todos los ameloblastomas, comúnmente se le encuentra en la mandíbula, es el menos agresivo que otros tipos de ameloblastoma y se presenta inusualmente en niños.  Se reporta caso de ameloblastoma uniquístico en una niña de 9 años, localizado en la región anterior de la mandíbula y de gran tamaño, se describen las características de la patología, tratamiento quirúrgico conservador y controles postquirúrgicos.
La Tea: el proceso de modernización de la poesía peruana como rizoma
Authors: Luján Sandoval Sergio
Published: March 2022

El presente artículo se ocupa de La Tea1, revista puneña que se ubica entre los horizontes del modernismo y del inicio de las vanguardias literarias en el Perú, respectivamente. La hipótesis que intentamos demostrar es la siguiente: en La Tea existe una dinámica germinal rizomática que forma parte del proceso de modernización de la poesía peruana. En tal sentido, analizaremos las variaciones del discurso poético, pues sostenemos que estos textos transitan por el modernismo, el posmodernismo e, incluso, presentan visos de los códigos vanguardistas. Para ello, emplearemos el concepto de rizoma propuesto por Gilles Deleuze y Félix Guattari, el cual nos permitirá entender los desplazamientos, los desencuentros, los quiebres y el diálogo que estos periodos desarrollan.
Topological conjugacy of non-singular flows with two limit cycles on S2×S1
Authors: Dobrolyubova Alisa L. , Kruglov Vladislav E.
Published: March 2022

In the paper, non-singular flows with two limit cycles on the manifold S2×S1 are considered. For such flows, a classification is obtained up to topological conjugacy, and it is shown that they have a functional modulus of stability. Since the functional modulus of stability takes on its own value for each fixed argument, the presence of such modulus implies the presence of an infinite number of numerical moduli of stability. To obtain this result, linearization is carried out in the neighbourhoods of two limit cycles using the construction from the work by M. Irwin. A result is obtained on the presence of a two-dimensional foliation in a neighborhood of the limit cycle; this foliation is invariant up to topological conjugacy. Existence of the functional modulus of stability follows from the presence of such foliations. Namely, when considering the intersection of two foliations and, accordingly, two linearizations acting in the basins of two limit cycles, the desired functional modulus is a map describing the relative position of the foliation layer in the neighborhood of the first limit cycle relative to the layer of the second limit cycle. The results are used from the work by Pochinka O. V. and Shubin D. D. on exactly two classes of topological equivalence of flows in the class under consideration and on description of their differences. The work includes figure which shows 2 classes of topological conjugacy of flows from the classes studied. Also there is a figure which shows the process of gluing R3 into a manifold with a stable limit cycle. Moreover, the construction of a solid torus is shown. The figures show consistent and inconsistent orientation of limit cycles, as well as invariant foliations. Also there is a figure which shows the functional modulus.
MANAJEMEN KEPALA SEKOLAH DALAM MENINGKATAN MUTU PENDIDIK
Authors: Delanda Puja Dwi , Sermal Sermal , Usdarisman Usdarisman
Published: March 2022

The purpose of the study was to determine the principal's management in improving educators. This study uses a descriptive method, with interview data collection techniques and documentation. Data analysis techniques in research are data collection, data reduction, data presentation and conclusions. The results of this study indicate that the principal uses management in the management of improving the quality of education which includes; 1) Planning; 2) Organizing; 3) Implementation; and 4) Control.
BUDAYA ORGANISASI TENAGA KEPENDIDIKAN DI SEKOLAH MENENGAH KEJURUAN (SMK) NEGERI 2 PAYAKUMBUH
Authors: Faizah Umu , Samad Duski , Ahmad Aprizal
Published: March 2022

Organizational culture is considered important because it is expected to have an effect on the final results of the school and become the foundation in carrying out activities within the organization. At the Vocational High School 2 Payakumbuh, also has an organizational culture that provides characteristics as a differentiator with other organizations. The author directly goes to the field or research location in order to obtain data or information that is expected to be able to reveal facts, phenomena, and to explain how the organizational culture in the State 2 Payakumbuh Vocational High School is. From the results of the interviews and observations above, the authors can conclude that the organizational culture in the Payakumbuh State Vocational High School 2, namely the principal and also the education staff builds a sense of concern for the institution, so it is hoped that the school will be better and also become more advanced. Vocational High School Negeri 2 Payakumbuh carries out activities related to organizational culture theory which consists of coordination/cooperation, discipline, innovation, reward, punishment, ease of communication, and socialization of organizational culture where the role of the leader is very important in disseminating the organizational culture itself to every employee. education in the school.
Generative Adversarial Network for an Improved Arabic Handwritten Characters Recognition
Authors: Alwaqfi Yazan , Mohamad Mumtazimah , Al-Taani Ahmad
Published: March 2022

Abstract Currently, Arabic character recognition remains one of the most complicated challenges in image processing and character identification. Many algorithms exist in neural networks, and one of the most interesting algorithms is called generative adversarial networks (GANs), where 2 neural networks fight against one another. A generative adversarial network has been successfully implemented in unsupervised learning and it led to outstanding achievements. Furthermore, this discriminator is used as a classifier in most generative adversarial networks by employing the binary sigmoid cross-entropy loss function. This research proposes employing sigmoid cross-entropy to recognize Arabic handwritten characters using multi-class GANs training algorithms. The proposed approach is evaluated on a dataset of 16800 Arabic handwritten characters. When compared to other approaches, the experimental results indicate that the multi-class GANs approach performed well in terms of recognizing Arabic handwritten characters as it is 99.7% accurate. Keywords: Generative Adversarial Networks (GANs), Arabic Characters, Optical Character Recognition, Convolutional Neural Networks (CNNs).
Taxonomic Revision ofSpiranthera(Rutaceae)
Authors: Brito Lilian de Andrade , Pirani José Rubens
Published: March 2022

Abstract—Spiranthera(Rutaceae, Galipeeae) is a neotropical genus, recognizable mainly by the presence of trifoliate leaves, pentamerous flowers, exappendiculate filaments, spirally revolute anthers lacking a basal appendage, a campanulate disk, and anelongated gynophore. Species in this genus are mostly sciophilous treelets from South American rainforests, except forSpiranthera odoratissima, the most widespread species, which is a shrub inhabiting savannic formations and showing the widest morphological variation within the genus. In this taxonomic revision we present an extensive morphological analysis of the genus based on data from field work and from herbaria, an identification key, and descriptions and illustrations of the six species here recognized, including a new one from Iquitos, Peru. Also, we present updated information on the geographic distribution of the species, their habitats, and their morphological variability.
A NewMasdevallia(Pleurothallidinae: Orchidaceae) from the White-Sand Forests of the Central Amazon, Brazil
Authors: Pessoa Edlley M. , Karremans Adam P.
Published: March 2022

Abstract—Masdevallia britoi, a new species inMasdevalliasect.Minutae, is described and illustrated from the central Amazon in Brazil. It is similar toM. wendlanianabut differs by shorter sepals that are internally white, shorter oblong petals with a delicate tooth near the middle, shorter lip with deltoid marginal folds near the middle and three-denticulate apex, and shorter ovary. The new species grows in the white-sand forests locally known with the name Campinaranas. We also provide an identification key for the species ofMasdevalliafrom the Brazilian Amazon.
Bare singulars and relative measures in Brazilian Portuguese
Authors: Lima Suzi , Thomas Guillaume
Published: March 2022

Brazilian Portuguese has received much attention in the typology of noun phrases for being a language with a fully-fledged determiner system that also allows generalized bare singular nominals. This paper investigates the use of bare singulars in relative measure constructions, such as um terço de mulher (literally, ‘one third of woman’). We show that Ahn & Sauerland’s (2015, 2017) and Pasternak & Sauerland’s (2020) analysis of relative measure constructions, combined with existing theories of bare singulars, predicts that bare singulars should be attested in relative measure constructions and derives their range of attested interpretations in these constructions. At the same time, we argue that these combined analyses predict that bare singulars should be attested in relative measure constructions in other Romance languages. This prediction is problematic and highlights the need for further research on the interaction of bare singulars and relative measures.
Proposing a multiple infrastructure model for the utilization of bitcoin
Authors: Sherej Sharifi Azita , Zalaki Ghorbanpour Mousa
Published: March 2022

Today, one of the most important reasons for the pervasiveness of digital currencies is the unique benefits it provides to users, which can be attributed to the speed and efficiency of payments, especially overseas payments. This study aimed to provide a multiple infrastructure model for bitcoin use. This research has been done qualitatively using interview tools. The survey community consists of academic experts including Profesor universitarios specializingin the fields of digital currencies, e-commerce, international finance and finance, and empirical experts consisting of managers and experts of monetaryand financial organizations (banks, stock exchanges). The selection of samples is saturated and purposeful. Finally, 18 people were selected to answerthe interview questions. Data analysis was performed with the context theory (GT) approach. Based on the obtained results, 6 main networks, 14 maincomponents and 77 sub-components were obtained as multiple infrastructures for bitcoin use. The results also showed that economic and social infrastructure can affect the use of bitcoin. If there is funding to buy the necessary devices and welcome bitcoin in the community, bitcoin will be more usable as a digital and acceptable currency.
How realistic is the discourse of talent developing school?
Authors: TORTOP Hasan Said
Published: March 2022

A school model that develops talent is never realistic. I explained why this is not possible. Important tips have been given for families and educators who care about talent development after the pandemic. The pandemic has solved the codes of the EPGBU model and made it emerge as the most suitable gifted education model. The spread of this program model, which has goals and objectives in parallel with JEGYS, is important in terms of meeting the need for young scientists in the world. H.W. Wilson Education Source Fulltext is one of the education field indexes for promotions in Turkey, and JEGYS