bluuebunny/crossref_metadata_2025 huggingface dataset:
Cardiovascular Alterations Present in Systemic Lupus Erythematosus: Review of the Literature
Authors:   Universidad Autónoma de Querétaro. Santiago de Querétaro, México., Hernández Omar Alejandro Avila , Flores Manuel Enrique Vadillo ,   Universidad Autónoma de Guadalajara. Guadalajara, México., Dorantes Miguel Ángel Sánchez ,   Universidad Autónoma de Querétaro. Santiago de Querétaro, México., Segovia Diana Laura García ,   Universidad Autónoma del Estado de Hidalgo. Pachuca, Hidalgo.
Published: March 2023

Systemic lupus erythematosus (SLE) is a systemic inflammatory disease secondary to an autoimmune response that is characterized by the deposition of immune complexes that activate complement and cause tissue damage. The American College of Rheumatology (ACR, American College of Rheumatology) in 2012 established the new diagnostic criteria for SLE, identifying 17 criteria of which at least 4 must be met (at least one clinical, and one immunologic) or lupus nephritis as the sole criterion in the presence of antinuclear antibody (ANA) or double-stranded anti-DNA for diagnosis.1
Larva Migrans: Management for the First Contact Physician and Review of the Current Literature
Authors:   Hospital general de zona 67. Instituto Mexicano del Seguro Social. Apodaca, Nuevo León, México., Figueroa María Cristina Ponce , Hernández Susana González ,   Hospital General Dr. Dario Fernandez Fierro.Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. Ciudad de México, México., Luna Jaime Picazo ,   Hospital General de Zona 194 Instituto Mexicano del Seguro Social. Naucalpan de Juárez, México., Quej Jacqueline Edith Mut ,   Hospital General de Zona con Medicina Familiar 1. Instituto Mexicano del Seguro Social. Campeche, Campeche, México., Bonilla Nayeli Guadalupe Gonzalez ,   Hospital General de Zona con Medicina familiar 1.Instituto Mexicano del Seguro Social. La Paz, Baja California Sur, México.
Published: March 2023

Cutaneous larva migrans is a skin infection caused by the subcutaneous migration of larvae of different species of nematodes. Also called Creeping eruption or serpiginous eruption, it is an endemic skin parasitosis of tropical and subtropical areas with hot and humid climate. In our environment it is unusual, predominating in individuals who have come to these areas, although there are rare cases of acquisition in European countries. It was first described by Lee in 1874 and since then its prevalence has been increasing, affecting millions of people each year. It is an endemic process in tropical and subtropical areas. Due to growing immigration and booming travel to these geographical areas, its prevalence in developed countries has increased in recent decades. For all these reasons, we believe it appropriate to disclose the existence of this parasitic dermatosis among dermatologists and primary care physicians.
Relevance of Multiparametric Magnetic Resonance in the Evaluation of Patients with Prostate Cancer
Authors:   Hospital General Dr. Gaudencio González Garza Centro Médico Nacional La Raza. Instituto Mexicano del Seguro Social. Ciudad de México, México., Islas Gabriela Cruz , Campa Rafael Valdivia ,   Hospital general del estado de Sonora Dr. Ernesto Ramos Bours. Sonora, México., Cabañas José Guadalupe Rivera ,   Hospital General de Zona 194 Instituto Mexicano del Seguro Social. Naucalpan de Juárez, México., Padilla Fernando García ,   Facultad de Medicina de la Universidad Autónoma de México. Ciudad de México, México.
Published: March 2023

The relevance of the use of mpMRI (multiparameter prostate magnetic resonance imaging) to evaluate the prostate in the context of PCa diagnosis lies in its ability to visualize primarily high-grade cancerous lesions that may be missed in routine diagnostic biopsies. standard. In several studies, mpMRI has shown improved performance compared to clinical models in identifying candidates who will benefit most from different therapies such as SA. Although data on mpMRI of the prostate during follow-up in men undergoing SA are sparse, there is potential to significantly improve AS programs through more accurate selection of optimal candidates which could achieve more accurate identification of progression of prostate cancer. disease and a reduction in the number of biopsies that would be needed to retest patients.
Oral Submucous Fibrosis: Understanding the Disease through a Case Series
Authors:   Interns of Baba Jaswant Singh Dental College And Research Institute Ludhiana., Ahuja Mannika , Chaudhary Divam ,   Interns of Baba Jaswant Singh Dental College And Research Institute Ludhiana., Gupta Bhawna ,   Interns of Baba Jaswant Singh Dental College And Research Institute Ludhiana., Singh Maninderjit ,   Interns of Baba Jaswant Singh Dental College And Research Institute Ludhiana., Singh Arshdeep ,   Interns of Baba Jaswant Singh Dental College And Research Institute Ludhiana., Bansal Mohika ,   Interns of Baba Jaswant Singh Dental College And Research Institute Ludhiana.
Published: March 2023

‘Vidari’ is a crippling fibrotic disorder affecting mouth commonly seen in India and South East Asia. It’s always optimum and highly desirable to beat oral submucous fibrosis(OSMF) before it becomes oral cancer. OSMF is a huge dilemma for clinicians worldwide specifically in south east Asia due to elusive pathogenesis. The main characterstic of OSMF is the build up of fibrous tissue in the sub mucosal layer of mouth, which can lead to a loss of flexibility and movement in mouth and can cause difficulty in opening the mouth and speaking, as well as eating and swallowing.We are presenting a case series of OSMF highlighting the clinically observed features. These features might not be seen together.
Investigatory Studies on Pattern in Enhancement in Fine Particulate Matter in the Delhi during winters
Authors:   Department of Applied Science Bharati Vidyapeeth’s College of Engineering Paschim Vihar – 110063, Sehrawat Nitu , Chauhan Ritika ,   Department of Applied Science Bharati Vidyapeeth’s College of Engineering Paschim Vihar – 110063
Published: March 2023

Smog is a harmful mixture of fog, smoke, dust and air pollutants such as nitrogen oxides, volatile organic compounds etc. Ground ozone can cause distressing health effect. Smog is a complex atmospheric pollutant mixture consisting of ozone, a pollutant with adverse effects on human health, vegetation, and materials; other eye-irritant and phytotoxic pollutants (such as aldehydes and peroxyacetyl nitrates); nitrogen dioxide (cause of the “whiskey-brown” color in the Los-Angeles atmosphere); and fine particles that cause adverse health effects, reduce visibility, and cause the “brown cloud” phenomenon. Photochemical smog is produced by vehicular emission mainly. Here we are discussing chemistry of formation of PAN (Peroxyacetyl nitrate), its impact environment & human health.
Biodiversidad amenazada de interés para el turismo en la región litoral, Ecuador
Authors: Rosete Blandariz Sonia , Saltos Toala Gema Valeria , Sáenz Véliz Romina Stephania , Jiménez González Alfredo
Published: March 2023

Los bosques albergan a más del 80% de todas las especies terrestres de animales, plantas e insectos. Alrededor de un millón de especies de animales y plantas se encuentran en peligro de extinción. El objetivo de la investigación fue caracterizar la existencia de una brecha en el conocimiento de la biodiversidad amenazada de interés para el turismo en la región litoral. Se levantó la información mediante la revisión bibliográfica y encuestas a 145 informantes claves del área de estudio. Se listaron 312 especies en peligro de extinción, distribuidas en 24 ecosistemas naturales. Los usos fueron maderables (200 especies) medicinales (98), alimenticias (64), utilizadas para la confección de artesanías (35) y para la restauración ecológica (16). Se presentan (2) alternativas ecológicas, agrícolas (2) y naturales (2). Y, 4 acciones para preservar el paisaje de la región, en conjunto a 15 alternativas turísticas y de conservación (8) que permiten el resguardo de las especies y los ecosistemas naturales.
Aprendendo currículos para humanos com busca em árvore guiada por rede neural
Authors:   , Nova João Gabriel Gama Vila
Published: March 2023

Este trabalho avalia Levin Tree Search (LTS) como um modelo para aprender currículos para pessoas. Nós hipotetizamos que a ordem em que LTS aprende a resolver um conjunto de problemas pode ser usada para formar um currículo que auxilia o aprendizado de humanos. Nós avaliamos LTS em dois esquemas de aprendizagem de currículos. Primeiro, ordenamos um pequeno conjunto de instâncias de problemas de acordo com a ordem em que LTS as resolve enquanto aprende uma política neural. Segundo, usamos LTS para ordenar um grande conjunto de instâncias de problemas e selecionamos um subconjunto deste para formar um currículo. Nós avaliamos o currículo que LTS gera através de um estudo com usuários em que os participantes aprendem a resolver uma classe de puzzles do jogo The Witness. Resultados computacionais mostram que a ordem que LTS encontra para o conjunto de instancias do jogo é a mesma ordem escolhida pelo game designer do jogo. O resultado do estudo com usuários sugere que o currículo que nosso sistema gera se compara favoravelmente com currículos de base em termos de retenção de usuário e número de tentativas para que se consiga resolver uma instância. Nossos experimentos computacionais e estudos com usuários sugerem que LTS utilizando uma política neural pode ser usada como um efetivo modelo de geração de currículos de ensino para auxiliar o aprendizado de pessoas em problemas de decisão sequencial. Palavras-chave: Educação. Busca em Árvore. Jogos.
Protein bioinformatics: overview and computational strategies to determine protein interaction patterns to assist in disease control
Authors:   , Gomes Isabela de Souza
Published: March 2023

Proteins are fundamental biomolecules for the metabolism of living beings and have several biotechnological uses. The computational study of this class of macromolecules allows the ex- pansion of knowledge and speed in research applications, such as catalytic processes, three- dimensional conformations, enzyme inhibition, molecular engineering, among others. In this dissertation, we present a set of papers that purposes computational strategies to study three- dimensional structures of proteins. In the ﬁrst work, we combine an in-house developed machine learning strategy with docking, MM-PBSA, and metadynamics simulations to detect potential inhibitors for SARS-COV-2 main protease. Computational strategies can help to speed up the process of drug discovery, reducing the time and cost of wet-lab experiments because they will be focused on fewer molecules. Our work points out six ligands that have a good interaction with our target in its active pocket, indicating an inhibitor behavior. We highlighted the strongest interaction of our experiments, M pro -mirabegron complex, which was used as input for subse- quent in vitro assays to validate the inhibition potential suggested by in silico experiments. In the second paper, we present a literature review of several bioinformatics tools for the study of proteins. The article is a very detailed material to support the choice of students and profession- als for the most appropriate tool for a particular application. In the third work, we introduced the Propedia database for protein-peptide identiﬁcation, which comprises over 19,000 high- resolution structures from the Protein Data Bank. Protein-peptide interactions can be useful for predicting, classifying, and scoring complexes or for designing new molecules. The main ad- vantage of Propedia over other peptide databases is that it allows a more comprehensive analysis of similarity and redundancy. The papers presented here provide an overview of the diversity of protein bioinformatics study and some of its applications in biological problems. Keywords: Bioinformatics. Protein-protein interaction. Peptide-protein interaction. Machine learning. Docking. Molecular dynamics. Proteins.
Last mile delivery with lockers, formulations and heuristics
Authors:   , Oliveira Willian Jorge Pereira
Published: March 2023

The demand for delivering goods to individuals has increased due to several factors such as urbanization, the growth of e-commerce, and the popularization of the internet. There are several challenges to deal and in the face of this, there is a constant search for new alternatives. In this scenario, among other solutions, lockers emerged, which are cabinets equipped with a self-collection interface, strategically positioned to serve customers asynchronously. In this work, we approach different formulations of the last mile delivery problem with lockers, considering the size of parcels and compartments and the probabilistic characteristic of the problem due to uncertainty about users accepting to use the locker. In all formulations, the objective is to decide the location of lockers and vehicle routes in order to minimize the cost of last-mile delivery. For this, we propose heuristics and mathematical models to deal with different problems, we create instances based on real data, and we perform several computational tests. We evaluated different scenarios and estimate how much the use of lockers can generate savings. In the probabilistic problem, we were able to simulate different scenarios, where all users accept or reject the use of lockers. Doing this, we were able to measure the savings that the use of lockers can generate and, thus, make decisions about the investment to be made in the construction and promotion of the use of lockers. Keywords: Combinatorial optimization. Vehicle routing. Facility location. Location Routing Problem. Last mile delivery. Parcel Lockers.
Optimization of the Electrical Conductivity of Copper Phthalocyanine Based Ink Applicable by Screen Printing on Textile Materials
Authors:   Organic Synthesis, Extraction and Valorisation Laboratory (SOEV) faculty of Sciences Ain Chock, Hassan II University. Km 8 Route d'El Jadida, B.P 5366 Maarif 20100. Casablanca, Morocco, Mohamed Tahiri
Published: March 2023

We report results on the conductivity of conductive ink based on copper phthalocyanine (CuPc), which contain different organic solvents, i.e. dimethylsulfoxide (DMSO) or Tetrahydrofuran (THF), and with different percentage of copper phthalocyanine.
Petrography and Mineralogy of Manganese Nodules Around Madaka, Tegina Sheet 143 SE, North Central Nigeria
Authors:   Department of Geosciences, Nigerian Institute of Mining and Geosciences, Tudun Wada, Jos, Plateau State, Nigeria, Ojo Adeoye Akintola
Published: March 2023

Petrographical and mineralogical characterization of manganese nodules around Madaka, north central Nigeria has been examined using ore microscopy and X-ray Diffraction for the clay in the study area.
Profile of Serum Vitamin D Levels Among Individuals in Mizoram: A Retrospective Study
Authors:   Associate Professor, Department of Surgery, Zoram Medical College, India, Vanlalhlua Chawngthu
Published: March 2023

Although there are innumerable studies on vitamin D deficiency in India, there is limited data in Mizoram. Keeping this in view the aim of our study is to find out the deficiency of Vitamin D in our region, Mizoram (NE India).
Sejarah Atau Asal Usul Mushaf AlQur’an di Sumatera Utara : Studi Terhadap Mushaf AlQur’an Dengan Iluminasi Melayu Pantai Timur Yang Ada di Museum Sejarah AlQur’an sumut
Authors: Nailan Rahma Nst Nailan Rahma Nst Nailan Rahma Nst
Published: March 2023

Mushaf Alquran di Sumatera Timur diabadikan dalam jurnal ini. Dalam sejarah masuknya Islam ke Indonesia, ada sebuah nama daerah yang melegenda di Sumatera Utara. Bisa dikatakan, batu nisan Islam kuno dapat ditemukan di seluruh Sumatera Utara, tapi anehnya, tidak ada tanda-tanda mushaf Alquran kuno. Di mana mushaf Alquran kuno yang digunakan oleh para ulama di Sumatera Utara sejak abad ke-14 dan memiliki ribuan saksi yang batu nisannya tetap diam? Sejarawan dan ketua Pusat Kajian Sejarah dan Ilmu Sosial (Pussis) UNIMED, Mr. Dr. Phil, terus memikirkan pertanyaan ini. MS Ichwan AzhariIchwan Azhari berpendapat bahwa Sumatera Utara memiliki banyak potensi untuk kehadiran Mushaf Al-Qur'an karena banyak sekali tanda-tanda bahwa Islam sudah ada sejak lama, setidaknya tanda-tanda bahwa Ulama sudah ada sejak abad ke-14. Kemungkinan keberadaan mushaf, di sisi lain, belum dipublikasikan. Namun, sebagian besar o F informasi menyebutkan, karena harganya yang menggiurkan, banyak Mushaf Al-Qur'an kuno dari Sumatera Utara, baik dari Pantai Barat maupun Pantai Timur, dibeli oleh pedagang dan kolektor barang antik dan dijual ke Malaysia. Mushaf Al-Qur'an Kuno dari Sumatera Utara yang semula disimpan di kantor Pussis UNIMED, mulai dikoleksi dan dipelihara hingga saat ini. Konsep pendirian Museum Sejarah Al-Qur'an Sumatera Utara bermula dari sini.
Penerimaan Honor/Upah Advokat dalam Perspektif Hukum Islam
Authors: Berutu Agustina , Hanan Aulia Fahira , Lubis Fauziah
Published: March 2023

In every job, honesty and great accountability are needed, especially in carrying out the mandate entrusted to workers, especially being an advocate. every problem from his client. In determining the honorarium for his client, he must pay attention to the condition of his client and in Islamic law there is no regulation regarding the halal or unlawful honorarium received by advocates in carrying out their work. his clients in the perspective of Islamic law and the purpose of this research is to find out the halalness of receiving honorariums in the perspective of Islamic law using the juridical-normative research method. The results of the study indicate that the honorarium paid ima by an advocate is lawful if the money received is not the result of fraud between the client and the advocate and justifies any means to win the client's case.

Keywords: advocate, honorarium, halal
A Case Study of the Revision of Village Rules as a Practical Strategy for Gender Equality Village Building in Jeju
Authors:   Society for Jeju Studies, Yeum Mi-Gyeung
Published: March 2023

This paper examines the aspects and characteristics of gender equality village building by local governments promoted against the backdrop of the women-friendly city policy of the Ministry of Gender Equality and Family through the case of a rural village in Jeju that led to the revision of gender equality village rules. As a result of the analysis, the following points can be found. First of all, finding out issues that can expand the participation of major actors and strengthening the cooperative implementation system among them played an important role in achieving certain results in the gender equality village building in the case area. Next, most rural villages are undergoing changes in population composition, and a new autonomy movement combining issues such as culture and environment in addition to gender equality issues is emerging, raising cases of conflict over village rules and the need for revision. The solution can also be said to be a task thrown into the case area. In addition, the project to revise the village rules for gender equality promoted in Jeju did not proceed smoothly in all villages, and there were some villages that delayed the revision of the village rules or failed to pass the village rules revision agenda at the village assembly. When it is said that even sea water itself does not guarantee the realization of village autonomy, a comparative study on villages that attempted to amend the village rules is necessary.
Jeju-ASEAN+α Policy: Toward a City Diplomacy of Peace, Ecology, and Inclusion
Authors:   Society for Jeju Studies, Kang Soo-Jeong , Gong Min-Seok
Published: March 2023

The main purpose of this study is to examine the limits and possibilities of Jeju-ASEAN+α policy and to search for an effective way for its development as a city diplomacy. Jeju-ASEAN+α policy is of paramount importance because it is an attempt to promote ‘diplomatic decentralization’ and diplomatic autonomy of a local government. Nevertheless, it is narrowly focused on economic issues, and therefore the core value of the policy could not be clearly defined. Deficiencies in the participation of civil society and the integrated governance structure of policy implementation are also significant problems. This study proposes three alternatives regarding core values of the policy, citizens’ participation in the policy processes, and governance structure of the policy. First, in terms of core values, Jeju-ASEAN+α policy should follow peace, ecology, and inclusion, which are the common elements of successful city diplomacies. Second, to enhance legitimacy and sustainability of the policy, citizen’s demands should be embraced and their participation in the policy process should be encouraged. Last, but not least, to reinforce effectiveness and sustainability of the policy, it is necessary to systematize the structure of governance that integrates multiple actors ranging from local government to NGOs and each citizens. In addition, legal and institutional support is also essential in this light. Jeju-ASEAN+α policy is not just a single policy, but it is a critical opportunity to establish the grand strategy of Jeju island’s city diplomacy. Its development and outcome would be the cornerstone of Jeju’s international renown as an innovative leader in the field of city diplomacy.
The Re-examination and Historical Significance of the Great Victory of Jeju along Eulmyo Japanese Invasion
Authors:   Society for Jeju Studies, Hong Ki-Pyo
Published: March 2023

Eulmyo Japanese Invasion occurred in May 1555(King Myeongjong 10), Japanese raiders with about 70 ships invading on the south coast of Jeollanam-do province. They gathered off the coast of Jeju Island on June 21 of the same year after retreating from Jeolla-do to great damage. About 1,000 Japanese raiders with 40 ships headed straight to Jeju Castle through Hwabukpo port on June 27. There was a three-day battle between Dongsung(east gate) of Jeju Castle and Sanjicheon stream(Namsugak). At that time, Kim soo-moon, a Jeju minister, made the first strike, selecting 70-member special forces(驍勇軍). Four of them including Kim jik-son, Kim sung-jo, Lee hi-joon, Moon si-bong swept the enemy lines riding horses and Kim mong-keun shot an enemy general down with an arrow. Since then, the people of Jeju were standing a good chance of winning and had a great victory, cutting many Japanese pirates off their throats and capturing them. This was not just Jeju’s victory, but it resulted in the final victory of Eulmyo Japanese Invasion in Joseon Dynasty. It played a major role in East Asian peace settlement at that time.
Analysis of the feasibility of the axiomatic principles of statistical physics
Authors:   Khoja Akhmet Yassawi International Kazakh-Turkish University, Dossymov Ye. , Makhmudov D. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University
Published: March 2023

Analyzing scientific works and researches in this article, we were convinced that today, in accordance with modern requirements, there is still a need to find a solution to the methodological features of teaching statistical physics in higher educational institutions, the methods and ways of organizing educational activities that form the interest of students. In order to realize the possibilities of statistical physics in higher educational institutions, the purpose, methods and content of teaching it as a subject should be interdisciplinary in accordance with the knowledge and skills of the student in special subjects. Therefore, in the creation of a methodological system of teaching statistical physics in a professional direction in higher education organizations, it is important to create opportunities for the development of visual intuitive foundations and practical orientation, to accept concepts, conclusions and problems related to the future profession of the learner with ways of thinking, while implementing interdisciplinary communication with special subjects. Thus, the contradiction between the need to teach statistical physics in a professional direction and its unsatisfactory solution in practice has become the reason for the relevance of the research topic. In order to train future professionals, the content of the statistical physics course should be selected in the direction of forming the methodological skills necessary for the future professional activities of the students. All of the above was the basis for choosing the research topic "Creating the interest of students by using innovative methods in the teaching of the statistical physics course" and determining its importance. The purpose of the work: to improve the teaching management system at different stages of the lesson, to strengthen the motivation to study, to increase the quality of education and training, to increase the level of preparation of students in the subject of statistical physics.
Influence of electrolytic plasma treatment on the physical and mechanical properties of steels
Authors:   Khoja Akhmet Yassawi International Kazakh-Turkish University, Zhumaliyeva А. , Kurbanbekov Sh. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University, Usembaeva I. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University
Published: March 2023

This article presents an overview of research data on new electrochemical processing processes, classified under the general name of the process of electrolytic-plasma surface heat treatment from various research papers. The review is made to expand the research work on this new process of industrial vision and coverage. Particular attention is paid to the prospects of its use for modifying and coating surfaces. Various types of electrolytic plasma treatment have been discussed to illustrate the possibilities of the process for improving the surface properties of various metals. Compared to existing heat treatment processes, the treatment takes less time, is economical, environmentally friendly and dynamic. Its dynamic capabilities include carburizing, nitriding, plating, cleaning, polishing, etc. to harden in one pilot plant by making small changes to enable operations. The processing modes and composition of electrolytes, structural features of the processed layers, their microhardness and surface roughness, tribological and anticorrosion, i.e. physical and mechanical properties in various environments. In general, processing modes have been determined that allow a significant increase in the antiwear and corrosion resistance of steels. A conclusion is made about the prospects of electrolytic-plasma treatment, the advantages and limitations of this method are noted, including the proposed directions for further research.
Web design or website planning
Authors:   Khoja Akhmet Yassawi International Kazakh-Turkish University, Baimurzayev B. , Kazbekova G. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University
Published: March 2023

The Internet and Internet technologies, unlike the 2010s, continue to spread around the world and retain their importance. Every day, people's access to the virtual world and the virtual network provided by the Internet is becoming more and more. In addition, the activity of websites increases, and with them the number of users visiting the sites. Types of web design are becoming wider and faster than with the increase in the number of websites, it follows that an important phenomenon in terms of what is happening in the virtual world can be said to be visual web design. The features of Web design that help to make design decisions and turn them into practice both in work and in everyday life were discussed in the sections «visual design for the Internet», «elements of visual design», «fundamentals of visual design principles». A device reflecting the style of writing about the types and styles of writing Web design was shown in the section: Spector. The website loading time, colors and usability of the website screen were displayed in the sections «color balance», «images», «overview» or «navigation», «table-based layout», «loading time», «mobile phone usability». For Website design, it is not possible to immediately start coding or visual design using various programs. First of all, it is necessary to plan carefully, during the planning process, the content and colors of the site are determined. It is necessary to logically organize, determine the needs of the user, determine how to provide navigation for the site. Visual design elements for a Website; can be viewed as purpose, communication, fonts, colors, images, navigation, table-based layout, template design «F», loading time and convenience for mobile devices.
Aplication of the Criminal Law in time as for Thefts (art. 228- 229)
Authors: Moise Andrei Emil
Published: March 2023

The penal law contains an ensemble of norms; rules of conduit which are enforced by criminal penalties. The penal law in reagard of theft is mandatory from the moment of its enforcement and it lasts, in time, until its abrogation. During the time of the enforcement, the penal law is active and is applied to all committed offences. Time limitation of the penal law represents an important part of the theory of penal law, first, because the penal law enforcement is limited in time, and second, the offences are committed in relation with the penal law. So, the penal law is applied to all crimes against patrimony offences committed while the penal law is enforced (active).The penal law doesn’t apply to the offences committed prior to its enforcement (the law is not retroactive), or to those committed after the law was abrogated (ultraactivity).The study also refers to the situation of concurrence of the offencesinregard to theft crimes, the duration and limits of the efficiency of the penal law, retroactivity, and abolition of an offence, applying the mitior lex principle, the cases when the penal law is retroactive or ultraactive.
Comparation of Discovery Learning Model and Cooperative Model on Writing Procedure Text of Vocational Students
Authors: Takdir Marlina , Ramly Ramly , Mayong Mayong
Published: March 2023

The purpose of this research is to examine how the skills of writing instructional texts and the learning results of Indonesian topics differ for students who are exposed to the Exploration Learning learning model versus those who are exposed to the Collaboration learning model. SMK Negeri 1 Pinrang served as the study site. Using a quasi-experimental technique with a pre- and post-test setup, samples from two groups will be randomly assigned to receive one of several therapies. About 30 pupils make up a typical classroom. We used a random selection method to collect our data. Class XI MM 2 served as the experimental group's implementation of the Discovering Learning model, while class XI MM 3 served as the control group's implementation of the Collaboration model. Final exams, comprised of multiple-choice questions, were administered to pupils in order to collect data for the study. The findings of the data analysis (t test), specifically tcount = 0.476, suggest that when it comes to teaching Indonesian topics, the Exploration Learning model yields superior results to the Collaboration model. After comparing them to a significance threshold of 0.05, we conclude that H0 cannot be supported. Students who engage in the Exploration Learning approach to education have higher learning results (average score of 85.66) than those who engage in the Collaboration approach (average score of 84.83). On average, students who are instructed using the Exploration Learning approach perform better than those whose education is based on the Collaboration approach.
Naar een nieuw geïntegreerd gemengd financieringsmodel voor de huisartspraktijk
Authors: Detremerie T. , Vansintejan J. , De Lepeleire J. , De Maeseneer J.
Published: March 2023

A new integrated mixed payment model for general practitioners in Belgium

Belgian primary care faces a number of challenges, exacerbated by the COVID-19 pandemic: an increasing percentage of elderly people, changing family structures, a shrinking labour market, health inequities, rapid and sometimes costly technological innovations, etc. The ‘quintuple aim’ was set as a goal to organise equitable and cost-effective, high-quality care to secure the health of citizens and the well-being of healthcare workers. There’s a growing consensus that a dominantly fee-for-service system is not fit to respond to the challenges. This article proposes a third mixed payment model, besides the 2 existing models, i.e. a fee for service and a capitation model. In this new model, the general practitioner’s income will be based for 60/70% on capitation and for 40/30% on fee for service. The income via capitation will depend on the characteristics of the patient population (age, socioeconomic status and maybe gender). Important conditions to implement this new model are a complete registration of all citizens in a primary care practice as well as monitoring of the number of consultations and home visits. Importantly, all forms of teleconsultations will be paid under the capitation part and the face-to-face encounters under the fee-for-service system. This new mixed model may cause some income shifts between general practitioners. Therefore, a thorough simulation at practice and care provider level is necessary before implementation.
Maktabgacha ta’lim tashkilotlari va oila oʻrtasida hamkorlikni yoʻlga qoʻyishda Finlyandiya tajribasini tatbiq etish usullari
Authors: Zaynidinova Zulxumor , Abbosova Aziza , Barotova Shoxsanam
Published: March 2023

Dunyoga mashhur Finlyandiyaning erta bolalik ta’limiga ya’ni maktabgacha taʼlim tizimiga alohida ahamiyat qaratadi. Finlyandiya ta’lim tizimi oʻnlab yillar davomida sinchkovlik bilan sinovdan oʻtgan va ajoyib natijalarga erishgan. U ta’limning eng yuqori standartlariga javob berish uchun eng yaxshi va eng yangi oʻrganish falsafalari, modellari, amaliyotlarini uzluksiz rivojlanish bilan birlashtiradi. Ushbu maqolada, maktabgacha taʼlim tashkilotlari va oila oʻrtasidagi hamkorlikni yoʻlga qoʻyish, taʼlim jarayonlariga turli yangiliklar olib kirishda Finlyandiya mamlakatining tajribasidan foydalanish haqida fikr va mulohazalar qilinadi.
Xalqaro tadqiqotlarda Finlyandiya ta’lim tizimining o‘rganilishi
Authors: Yusupova Shohida , Kuziyeva Gulnoza
Published: March 2023

Ushbu maqolada Finlandiya ta’lim tizimining joriy etilishi, fin ta’lim tizimidagi bo‘g ‘inlari, quyi ta’lim, o‘rta ta’lim, fin maktablaridagi darsliklar, o‘qituvchilarning ish faoliyati, maktabdagi o‘quvchilarga berilgan imkoniyatlar haqida batafsil ma’lumot berilgan.
Theoretical basis youth marginalization
Authors: Jurayev Jamshed
Published: March 2023

This article analyzes the processes of marginalization of young people in the social structure and the processes of the emergence of marginal strata and statuses. The author describes and justifies the state of marginal status in the social structure of the modern community.
An Evaluation Of Parents Of Toddlers' Knowledge, Attitudes, And Practices Regarding Exposure To Electronic Media
Authors: Vartika Vishnoi
Published: March 2023

An extensive review of literature was done from published and unpublished articles, books, documents and reports. It has provided a deeper insight into problem and has assisted in methodology, defining the problem, recognizing the significance formation of conceptual framework and analysis of data. The review of literature for the present study has been organized under the headings.
Formulation And Evaluation Of Berberine Hydrochloride Film Coated Tablet
Authors: Manju Koli
Published: March 2023

The purpose of the present study was to formulate and evaluate Berberine HCl Film coated tablet. Preformulation studies of API were done. The film coated tablets have advantages over conventional oral dosage forms, film coated tablet also influences the release of drug after compression. Film coating also help in making the tablet with good taste masking properties and excellent mechanical strength. It was revealed in the study that cellulosic coating materials were unable to resist the compression forces whereas hydroxypropyl methyl cellulose co-polymers resist the forces. Furthermore, aqueous dispersions of hydroxypropyl methyl cellulose co-polymers showed high flexibility as that of cellulosic materials thereby providing resistance from destructive compressional forces. The Preformulation characteristics were done as per the Pharmacopeial specifications. The drugs and excipients compatibility studies were carried out by FT-IR spectroscopy. Various pre-compressional parameters like bulk density, tapped density, compressibility index and Hausner’s ratio and post-compressional parameters like weight variation, thickness, hardness, friability, disintegration time and drug release were studied. The spectra elucidate that there was no interaction between Drug and excipients. In order to achieve the best optimized product, five different formulations were developed using diluents, binder, glidant, lubricant, and different concentrations of super-disintegrant. The tablets were prepared by using wet granulation method. Optimization was done and it was found that release profile was found to be best with super-disintegrant that is Crospovidone and Enhance DT. Protectab HP-1 coating was done on Berberine HCl tablets. In-vitro release was carried out in medium 6.8 pH Phosphate buffer. The formulation F-5 was showed better drug release and selected as an optimized formulation.
In-Silico Drug Design And Adme Studies Of Substituted 1, 3, 4-Oxadiazole Analogues As Potent Mycobacterial Dpre1 Enzyme Inhibitors
Authors: Rekha S
Published: March 2023

Mycobacterial infections and multidrug-resistant (MDR) strains of Mycobacterium generate high mortality, this has triggered the scientific community to search for novel, effective, and safer therapeutics. A series of 4, 5-disubstituted-1, 3, 4-oxadiazole derivatives were screened for mycobacterial activity against H37Rv, MDR and XDR strains. To recognize the mechanism of action of these compounds and to identify their supposed drug target, molecular docking and dynamics studies were employed against DprE1 mycobacterial enzyme, which is reported to be an essential enzyme for mycobacterial growth and survival. The ADME and drug-likeness properties revealed that all the compounds have good pharmacokinetic properties. All the compounds have high affinity towards the enzyme. The newly synthesized derivatives were confirmed through FT-IR, 1 H-NMR, and LCMS. In-vitro microplate alamar blue assay (MABA) to determine the MIC (minimum inhibitory concentration) values against Mycobacterium tuberculosis H37Rv was performed for the synthesized compounds. The synthesized compounds 2A, 3A, 4A, 5A and 6A exhibited promising activity against Mycobacterium tuberculosis.
A TRANSMISSÃO INTERGERACIONAL DA POBREZA – UMA BREVE ANÁLISE DO CONTEXTO MOÇAMBICANO
Authors: Bule Jose Ernesto
Published: March 2023

A pobreza é uma condição que afecta um grande número de pessoas em todo mundo. Todavia os governos em todos países tendem a levar a cabo uma série de acções tendentes a combatê-la, em prol do bem-estar da sua população. Os factores associados à condição de pobreza são o principal motivo pelo qual são desenhados vários instrumentos para fazer face a ela. Esses factores variam de acordo com a posição económica dos países bem como a concepção predominante na sua população em termos de esforços individuais para sair dessa condição. Pretende-se com este ensaio analisar os factores que contribuem para a transmissão da pobreza entre gerações bem como as acções que podem ser levadas a cabo para se sair dessa condição. Para o efeito, irá se recorrer a pesquisa da bibliografia. Dentre os factores associados a pobreza estão os domésticos e os extradomiciliares como preponderantes para mergulhar ou não um indivíduo na teia da pobreza. Deste modo, investimento no capital humano, de tal forma que o indivíduo aproveite todas as potencialidades ao seu redor para sair da condição da pobreza mostra-se o caminho mais viável.
Timely Business Record Management Keeps a Business Safe An Opinion from Small and Medium Enterprises
Authors: Siddique Muhammad , Shar Zeenat Kanwal , Baig Mariya
Published: March 2023

The delayed recording of transactions creates risk for small and medium entrepreneurial businesses. This practice may become the cause of errors, and fraud in business records may suffer in the future. The study aims to create awareness among entrepreneurial businesses. The data was collected from 120 respondents by convenience sampling method. Used a well-developed and verified scale closed-ended questionnaire for primary data collection. Used SPSS and descriptive statistics for data analysis. The results showed that many irregularities occurred in small and medium entrepreneurial businesses due to the delayed recording of business transactions. Pointing out the delayed recordings of business transactions practice in small and medium entrepreneurial businesses is a grey area and is a novelty for this research. The guidelines may be followed by other small and medium enterprises for keeping them safe from irregularities.
Promoting Hospitals’ Reputation through Social Media and Artificial Intelligence
Authors: Medina Aguerrebere Pablo , Medina Eva , González Pacanowski Toni
Published: March 2023

Cancer hospitals resort to social media platforms to make their corporate communication initiatives more dynamic and this way better satisfy their stakeholders’ needs in terms of medical information and emotional support. Nevertheless, these organizations also face different barriers such as new patients’ medical demands, legal issues, privacy or the difficulty to disseminate scientific content. To overcome these barriers, more and more hospitals integrate social media platforms and artificial intelligence-based tools into different medical protocols, and this way they proposed to patients a unique medical service, which positively impacts on patients’ satisfaction and the hospital’s corporate reputation. This literature review paper aims to analyze how artificial intelligence and social media platforms used in an integrated way help cancer hospitals to implement more efficient corporate communication initiatives in order to build a more reputed brand. To do that, we conducted a literature review about cancer hospitals’ corporate communication strategies, social media platforms and artificial intelligence in cancer hospitals; and then, we proposed ten managerial implications for helping cancer hospitals use both insights (social media and artificial intelligence tools) for building a reputed brand.
Records in manuscript and printed books as a source of information on the spread of book culture in the middle Volga region of the XVIIth century
Authors: Makarov Andrey I.
Published: March 2023

The study of books that through their origin and/or existence are connected with the territory of the Middle Volga Region of the XVIIth Century has revealed a large number of scribes, owners, deposit, gift and selling records made by representatives of different social classes. Some of them show the geography of book writing in the region, the cost of books, give additional information on local history and culture as well as the inhabitants of the region. The study is based on the information from bibliographic sources (catalogues) of regional and central libraries, museums and archives. In some cases, records in manuscript and printed books are described de visu.
Method Development and Validation of Assay of Chlorpromazine Hydrochloride Tablet Formulation using UV-Visible Spectrophotometer
Authors: Aarti Pawar  , Rekha Birle  , Dr. Nandu Kayande
Published: March 2023

The present study includes analytical method for determination of the drug Chlorpromazine Hydrochloride (CPH) in some Pharmaceuticals using Molecular Absorption, in addition to investigating complexes throughout. The analytical data obtained throughout this study could be summaries as follow. The method was found to be simple, safe, sensitive, and validated for the assay of chlorpromazine hydrochloride using phenol red, citrate buffer pH 3, and water as diluents. It was also found to be an accurate, reproducible, and cost-effective quality-control tool for the routine analysis of chlorpromazine hydrochloride in standard and pharmaceutical forms
Desigualdade racial no Brasil: desafios contemporâneos para o trabalho do professor de Educação Física
Authors: Vieira Junior João Carlos , Venancio Ananias Elisangela
Published: March 2023

O presente estudo configura-se como um artigo de revisão, cujo objetivo foi identificar o conhecimento dos professores de Educação Física sobre a Lei 10.639/2003 e como tratam situações de desigualdade racial a partir de sua prática pedagógica. Para tal, realizou-se uma busca no Portal de Periódicos da Capes, a partir dos descritores: desigualdade racial, discriminação racial, Educação Física, escola. Definiu-se como marco temporal os anos entre 2014 e 2019, para as publicações. A busca retornou com 64 artigos, dos quais foi feita a leitura dos títulos e resumos, destes foram selecionados quatro artigos. Como critérios de inclusão: estudos na área de Educação Física, sobre a temática desigualdade racial e discriminação racial, e estudos na educação básica. Como critérios de exclusão: estudos com professores de outros componentes curriculares; estudos que abordassem outras temáticas como gênero associadas; estudos em ambiente não-escolar. Concluiu-se que há fragilidades na formação inicial e continuada de professores de Educação Física, para que a temática seja abordada na Educação Física em situações de discriminação, mas também para que a Educação para as Relações Étnico-raciais seja adotada e incluída nos currículos escolares, além do desconhecimento dos professores sobre a Lei 10.639/03.
PEMBERDAYAAN MASYARAKAT DALAM PENINGKATAN BREASTFEEDING SELF-EFFICASY DI WILAYAH KERJA PUSKESMAS TUNAS HARAPAN
Authors: Fitri Andini Indah , Kurniyati Kurniyati , Susanti Eva
Published: March 2023

Breastfeeding Self Efficacy is a mother's belief to breastfeed her baby which influences effort, thought process and response when encountering difficulties in breastfeeding. The factors that influence a mother's self-efficacy are mastery experiences, other people's experiences, verbal persuasion, somatic and emotional conditions. The success of exclusive breastfeeding cannot be separated from the mother's factor, namely the desire and confidence of the mother to breastfeed. Mothers who have a high level of self-efficacy will breastfeed longer than mothers who have a low level of self-efficacy in breastfeeding. The solution offered by the implementing team was to increase the knowledge and skills of cadres through training on how to increase knowledge about breastfeeding self-efficacy for pregnant and breastfeeding women. The method for developing this activity was by providing training and refreshing for Posyandu cadres and village midwives as well as assisting cadres during the implementation of the activity. This activity achieved several results, namely the formation of ASI cadre groups through the WhatsApp media, and availability of facilities and infrastructure to support activities such as modules, tools and materials to increase the knowledge and skills of cadres on how to improve Breastfeeding Self Efficacy. After the training, there was an increase in the cadres' knowledge and skills about Breastfeeding Self-Efficacy.