bluuebunny/crossref_metadata_2025 huggingface dataset:
A prospective observational study of predictive factors for conversion of laparoscopic to open cholecystectomy
Authors: Singh Ajeet Kumar , Nayak Partha Sarathi , Dewangan Komal Prasad
Published: February 2024

Background: Cholelithiasis affects about 10 to 15% of general population. LC became the procedure of choice for management of symptomatic gallstone disease for its minimally invasive nature, minimal pain and earlier recovery.
Methods: This study was carried out on 300 consecutive patients who underwent LC for gall stone disease (patients falling under inclusion criteria) in the Department of General Surgery, The Calcutta Medical Research Institute, Kolkata.
Results: In this study 9% patient were converted to open cholecystectomy while 91% of the patient underwent successfully LC. Increased wall thickness of gall bladder (p=0.01), pericholecystic fluid collection (p=0.04), stone impaction at gall bladder neck (p=0.001), pain abdomen (acute cholecystitis, recurrent acute cholecystitis) (p=0.03), previous abdominal surgery (p=0.001), pre-operative jaundice (p=0.005) were found significant in this study for conversion to open surgery. Increased TLC, total bilirubin, alkaline phosphatase, alanine transaminase and aspartate transaminase (p<0.05) were also risk factors for conversion to open surgery.
Conclusions: We conclude that LC is the gold standard treatment for gall stone disease. Identification and safeguarding the bile ducts and arteries is of utmost importance while performing LC.
A case of retained surgical mop in abdomen with partial intragastric migration: a case report
Authors: Hossain M. Muktar
Published: February 2024

Though not uncommon, to retain a foreign body in the abdomen is a preventable error that makes the life of a patient miserable. One of the commonest retained foreign bodies is surgical mop or sponge. Retained mop may cause either an early septic reaction or a late fibrotic reaction. They often cause sinus or fistula and even can transmigrate in to the lumen of viscera. In case of upper abdominal retained mops, they usually erode the thin duodenal wall and rarely stomach. In this case, a mop was retained in the deep subhepatic space 2.5 months ago following open cholecystectomy. It caused an aseptic fibrotic reaction resulting in encapsulation of the mop. It then eroded the antral part of stomach through the lesser curvature and caused luminal obstruction. The patient presented with vomiting after each meal. Upper gastrointestinal tract (GIT) endoscopy revealed a woven fabric object that was impacted and occluded the lumen. The retained mop was removed after laparotomy and the antral wall was repaired well. This case is noteworthy due to its less symptom and penetration into the stomach.
Case report of high-grade pleomorphic sarcoma (rhabdomyosarcoma): a missed diagnosis in the non-healing post-traumatic wound of the elderly
Authors: Jain Shashank , Dama Shraddha , Beldar Nikhil L. , Mahadik Abhishek G. , Budhkar Abhijeet
Published: February 2024

Rhabdomyosarcoma (RMS) is known to be common childhood soft tissue sarcoma (STS). RMS is infrequent in adults. STS constitute <1% of all adult solid malignant sarcomas and RMS accounts for 3% of all STS. The tumor is divided into three main subtypes-embryonal, alveolar, and pleomorphic (most common in adults). The most common primary sites are extremities. It’s an aggressive lesion with a high rate of metastasis. The patient presented with a non-healing wound over a posterior-medial aspect of the right leg with features suggestive of cellulitis. The patient gave a history of fall 5 months ago for which he took treatment at a local doctor, he continued to have severe pain for which an orthopedic opinion was taken and advised conservative management for an un-displaced fracture of the fibula. He later developed swelling over the lower-middle part of his right leg 3 months ago for which an ultrasound was done suggestive of a large amount of fluid suspicious of hematoma secondary to A-V malformation, an attempt for drainage of fluid was made leading to an evacuation of blood clots further procedure was abandoned and the patient transferred to our center. CT-angio demonstrated it as a heterogeneously attenuating solid cystic lesion. After appropriate consents-wound exploration was done with the evacuation of soft gelatinous material with pus discharge and blood clots. HPE-suggestive of high-grade pleomorphic rhabdomyosarcoma. The patient was advised amputation but denied any further treatment. Post-operative recovery was uneventful with no recurrence for the first 6 months after which the patient did not follow up. Post-traumatic mass at extremities should be evaluated with a high index of suspicion of STS. In case of doubt, either a preoperative biopsy or an intraoperative frozen section is a safe practice.
Case report of rare gastrointestinal non-Hodgkin's lymphoma presenting as intussusception in adults
Authors: B. H. Sumanthareddy , Andley Manoj , Saha Sudipta , Singh Ranvir , Mustkim  , Singh Katyayni , Mishra Shashank
Published: February 2024

Gastrointestinal lymphomas comprise a group of distinct clinicopathological entities of B- or T- cell type, with primary gastrointestinal Hodgkin’s lymphoma being extremely uncommon. The gastrointestinal tract is the predominant site of extra-nodal non-Hodgkin's lymphoma accounting for 30-40% of all extra- nodal lymphomas.1 Most common non-Hodgkin’s lymphoma causing intussusception is diffuse large B-cell lymphoma (DLBCL). We herein report a rare case of ileo-colic Intussusception due to diffuse large B-cell lymphoma in a 42-year-old female. Computed tomography showed ileo-colic intussusception. Open hemicolectomy with ileo-colic anastomosis was done with postoperative chemotherapy.
Exposure of children to fine particles (PM2.5 and PM10) in schools in the health districts of Yopougon, Abidjan
Authors: Attoh-Toure Harvey , Oussou Konan Roland , Coulibaly M'Begnan , Soualihou Noufé , Konan N'Guessan , Gilbert Loukou Konan , Kouao René , Koné Mohamed , Tiembré Issaka , Dagnan Simplice N'Cho
Published: February 2024

Background: In Africa, the school environment is becoming a growing concern, as concentrations of fine particles inside classrooms are very high. We decided to estimate the level of exposure to PM2.5 and PM10 of schoolchildren in the health districts of Yopougon in Abidjan.
Methods: This was an analytical cross-sectional study of pupils aged 8 to 14 years in the health districts of Yopougon. Our study was conducted from 24 November 2020 to 18 January 2021. The pupils were selected by two-stage random sampling. A real-time fine-particle measurement instrument, the DYLOS 1700, and the ISAAC questionnaire were used to collect the parameters studied.
Results: We surveyed 881 pupils from 08 schools. The sex ratio (M/F) of the pupils was 0.9 and the mean age was 12 years. Measurements of PM2.5 and PM10 levels in the classrooms were 30 times higher than WHO standards and ranged from 200 to 1000 µg/m3 and 1000 to 3000 µg/m3 respectively. There was a significant link between the presence of pollution sites near schools and the increase in PM2.5 and PM10 levels in classrooms. Clinical manifestations suggestive of asthma in pupils were significantly associated with high levels of PM2.5 and PM10.
Conclusions: Pupils in Yopougon’s schools are exposed to high level of fine particle pollution that exceed WHO standards. Respecting and applying pollution reduction measures will help to create a school environment that is favourable to the respiratory health of pupils.
The impact of herpes zoster infection awareness program on myths, knowledge, and practices among the rural population of western Maharashtra
Authors: Goyal Sagar , Salgar Akshay , Dhavalshankh Gayatri G. , Dhavalshankh Ganesh P. , Dhavalshankh Archana G.
Published: February 2024

Background: In India, there is a paucity of population-based studies and data on herpes zoster in reporting herpes zoster cases. Several shreds of evidence reflect that the disease causes a burden on population health in India. Besides several known risk factors, myths, lack of knowledge, attitude, and practices towards treating this infection may affect the quality of life and disease burden. Imparting knowledge, awareness regarding myths and misconceptions, and early approaches for treatment can help prevent disease and complications in the population.
Methods: Our study variables were myths about herpes zoster infection, knowledge about herpes zoster infection, and attitudes and practices towards the treatment of herpes zoster infection and to evaluate the impact of health awareness programme on it. It is an interventional study where study population is the families of adopted villages by D.Y. Patil Medical College, Kolhapur from the rural population of western Maharashtra.
Results: The awareness programme which was the intervention in this study, was effective in increasing the awareness about myths and knowledge about herpes zoster infection as well as positive impact related to treatment practices for herpes zoster infection among the rural population in the adapted villages in western Maharashtra.
Conclusions: The awareness programme which was the intervention in this study, was effective in increasing the awareness about myths and knowledge about herpes zoster infection as well as positive impact related to treatment practices for herpes zoster infection among the rural population in the adapted villages in western Maharashtra.
Feasibility of tele-rehabilitation in low resource setting: perceived barriers and facilitators among physiotherapy professionals
Authors: Augustine Anulucia , Katalkar Priyadarshani , Kokal Divya
Published: February 2024

Background: Robust evidence illustrates the significance and efficacy of telerehabilitation to optimize the participation in rehabilitation program taking into account organisational, geographical and transportation aspects. Despite knowing the remarkable benefits, there exist an array of challenges to implement telerehabilitation services in a setting with meagre resources. In order to augment the uptake of telerehabilitation services, our study aims to explore the perceived barriers and facilitators to telerehabilitation among Physiotherapy professional in a resource limited setting.
Methods: A cross-sectional survey was conducted among physiotherapy professionals in Maharashtra using a questionnaire with a content validation index of 0.95. The survey sought to ascertain the awareness, barriers, facilitators and strategies to improve practice of telerehabilitation.
Results: A total of 450 Physiotherapists were invited, of which, 201 participated in the study. The major barriers to telerehabilitation were inaccuracy in obtaining adequate information (n=149, 74%), lack of face-to-face monitoring (n=131, 65%) and physical limitation in older adults (n=114, 57%); on the other hand, the facilitators were reduced transportation time to hospital/clinic (n=132, 67%) and improved accessibility to healthcare services (n=125, 62%). The factors that enabled the patients to participate were flexible appointment schedule (n=139, 69%) and minimal transportation costs (n=129, 64%). Furthermore, the participants majorly considered encouraging patients’ appropriate environment, insurance coverage, training and upskilling of clinicians as the strategies to improve practice.
Conclusions: The implementation of telerehabilitation program has been limited due to perceived constraints associated with various organizational, geographical and patient factors. However, physiotherapists reported strategies to improve practices could be implemented to accelerate the utilization of telerehabilitation services.
Decoding the diagnostic landscape of adnexal masses: a retrospective observational study at a tertiary care centre assessing the efficacy of the RMI-2 index
Authors: Shahu Sheetal , Asrani Manisha , Raithatha Nitin , Parmar Saurabh , Vaishnav Smruti , Bhattacharjee Rumi
Published: February 2024

Background: This study aimed to determine the utility of RMI 2 in distinguishing benign and malignant adnexal masses in low-income countries.
Methods: For the purpose of this retrospective observational study, relevant data from patients who attended a tertiary care institution in central Gujarat between June 2020 and June 2022 were obtained from the Medical Records Department (MRD). Ultrasound and biochemical parameters along with epidemiological factors were identified and an RMI 2 score was calculated followed by statistical analysis.
Results: Twenty-five (37.87%) of the sixty-six instances that were investigated were benign, two (3.03%) were borderline, and thirty-nine (59.09%), were malignant. Using RMI 2 at the traditional cut-off value of 250, results showed a sensitivity of 85.2% (95 %; CI=68.9-95.05), a specificity of 66.6% (95 %; CI=47.1-82.7 %), a positive predictive value of 74.36%, and a negative predictive value of 80.0 %. The ROC showed an AUC of 0.68 (CI=0.5-0.7) with a standard error of 0.07 (p=0.009).
Conclusions: With a cut-off point of 250, RMI 2 was able to identify malignant masses with an 85.2% sensitivity and 66.6% specificity to enable timely referral to more advanced institutions for improved management in resource-constrained settings where its affordability and user-friendliness are favourable.
Interesting case report on Chiari network
Authors: Kumar Dheeraj , Singh Gajram , Singh Mahendra , Singh Jyotsana
Published: February 2024

The Chiari network is a congenital remnant that is typically found in the right atrium and is generally not associated with significant pathophysiological implications. Usually, this is detected on general routine health checkup screening or casual examination. But, occasionally in certain cases, it is possible for this condition to results in diagnostic ambiguity when assessing right atrial disorders. Additionally, it has potential to contribute to the development of thromboembolism by inducing flow blockage. The Chiari network can be accurately diagnosed by echocardiography. This network appear as a highly mobile, highly reflectant echo target at many regions in the right atrium during transthoracic and transesophageal echocardiography. In this study, we provide a case involving an 18 year old male students studying cardiac technology who was diagnosed incidentally during echocardiography practical classes with Chiari network, mild TR and mild PR. The value and precision of echocardiography are becoming more widely recognized and being used more frequently. The potential for finding normal anatomical variations and their potential incorrect interpretation as pathological states coincides with the wider implementation of this imaging method.
Millets as nutri-cereals and its health benefits: an overview
Authors: Kothapalli Sivakumar , Ramalingam Sitharthan , Nair Soumya S.
Published: February 2024

Millets are one of the oldest foods known to humans, possibly the first cereal grain used for dietary. Since ancient times, millet has been widely consumed in Asia and India. Although millets are highly nutritious, their consumption still needs to be improved in the general and poor population due to less awareness regarding their nutritional values and health benefits. With changing food habits, increasing population, and uncontrolled use of natural resources, providing nutritious food to all is challenging. Natural plant resources are quickly depleting, and we must explore new alternatives. Besides the usual rice and wheat, many underutilized millets are less consumed, with great potential to replace routine cereal crops. Millets are one of the significantly underutilized crops with a nutri-cereal potential. Regular and excess consumption of common cereals contributed to developing and increasing the burden of lifestyle diseases. Millets are highly nutritious, gluten-free, and have rich dietary properties. Millets are rich in carbohydrates, dietary fibres, energy, essential fatty acids, proteins, vitamin B and minerals which help to prevent diseases like diabetes, hypertension, hyperlipidemia, cancer, cardiovascular diseases. Cereal-based food products are supplemented with millet and have become popular due to nutritional and economic advantages. The millets have fostered immunity and health to continue the fight against malnutrition in children and adolescents. Ultimately, millet consumption furthers nutrition, food security and the welfare of farmers. This review furnishes crucial information about the compounds found in millets, highlighting their nutraceutical properties, health benefits, and other therapeutically significant elements that classify them as nutri-cereals.
SEPULTURAS DE ESCRAVOS E A MATERIALIZAÇÃO DA DESIGUALDADE DIANTE DA MORTE NO RIO DE JANEIRO COLONIAL
Authors: Rodrigues Claudia , Soares Marcio de Sousa
Published: February 2024

O presente artigo busca analisar a complexidade dos enterramentos de escravos, entre 1730-1815, na igreja matriz da paróquia rural de Nossa Senhora da Apresentação de Irajá, localizada no recôncavo da Guanabara/Rio de Janeiro. Por meio do estudo de registros paroquiais de óbito, busca demonstrar as desigualdades e as hierarquias existentes no interior do cativeiro expressas na localização e na posição das covas. Os sepultamentos privilegiados se relacionavam às distintas posições que os cativos possuíam nas escravarias de Irajá. Dependendo da pertença a uma irmandade religiosa, da posição que ocupavam no interior do cativeiro e do prestígio social dos senhores, uma seleta fração de escravos obteve funerais diferenciados.
Application of Forward Chaining Method, Certainty Factor, and Bayes Theorem for Cattle Disease
Authors: Putra Fajar Rahardika Bahari , Fadlil Abdul , Umar Rusydi
Published: February 2024

Indonesia is a country that has many natural resources, especially mammals. The Papua and West Papua regions are large provinces with abundant natural resources and tremendous livestock potential. The availability of natural resources in the form of live cattle provides a great opportunity to develop animal husbandry in West Papua province. This research was conducted to create a new expert system with a knowledge base to solve the problems that occur and be useful for the community, especially cattle breeders. The current problem is the delay and lack of medical personnel in diagnosing cattle diseases, the distance that must be traveled, which is still very difficult to travel, and the lack of understanding of farmers in early handling when implications indicate animals. So, the Certainty Factor Method and Bayes Theorem with Forward-Chaining search are used to handle current problems. From the results of manual calculations, Certainty Factor Forward Chaining search is a method that has an uncertainty value of 99.84% for 3-day fever compared to Bayes Theorem Forward Chaining search with a value of 50% for worms, 50% for 3-day fever and 50% for nail rot, if applied then Certainty Factor Forward Chaining search is the most appropriate. Likewise, updating the knowledge base must be done from time to time. So that in the future, it can be compared with other methods and Android-based to facilitate current breeders.
Bienestar psicológico y comportamiento proambiental en un grupo de universitarios de nuevo ingreso
Authors: Sierra Barón Willian , Quiñonez González Eimy Mariana , Villalba Lugo Nayeli Valentina , Suarez Camacho Paula Andrea , Chilito Fierro María Alexandra , Medina Rojas Sergio Antonio
Published: February 2024

La comprensión de las relaciones entre el comportamiento proambiental y los recursos psicológicos se encuentra en un creciente desarrollo. Este es un estudio descriptivo-correlacional, comparativo- transversal realizado con 406 estudiantes, quienes respondieron las escalas de Comportamiento Proambiental y de Bienestar Psicológico, más una ficha sociodemográfica. Los resultados presentan niveles mayores en factores proambientales y niveles medios en factores del bienestar psicológico. Se identifican diferencias significativas entre los factores medidos respecto de la facultad a la que pertenecen. Existen correlaciones significativas entre los factores del bienestar psicológico y los factores proambientales, con menores magnitudes ante los factores antiambientales. La norma subjetiva y la autonomía son los predictores que mejor contribuyen a la intención del comportamiento proambiental. Se espera que el fortalecimiento de los factores señalados, en conjunto con el dominio del entorno y las creencias proambientales, pueden contribuir a una mayor intención de comportamiento proambiental; no obstante, se requieren más estudios que evalúen otras variables psicológicas implicadas.
Análise da rentabilidade das empresas inscritas no índice de sustentabilidade empresarial da B3
Authors: Oliveira Samara de , Santos Valterlin da Silva
Published: February 2024

Com as novas exigências da sociedade, as empresas tiveram de inovar e readaptar suas práticas empresariais na busca por diferencial competitivo e garantia na construção de valor a longo prazo. Nesse contexto, a sustentabilidade e a responsabilidade socioambiental têm assumido papel importante no moderno âmbito dos negócios, levando as empresas ao aperfeiçoamento das boas práticas de governança corporativa. Desta forma, o objetivo do estudo é investigar se a rentabilidade das empresas pertencentes a Brasil, Bolsa, Balcão (B3) apresentou alguma alteração após seu ingresso no Índice de Sustentabilidade Empresarial (ISE). Para atingir esta finalidade, a rentabilidade de uma a amostra composta por 20 empresas que se mantiveram de forma ininterrupta desde sua entrada na carteira ISE até o ano de 2018 foi analisada através do indicador de rentabilidade “Retorno Sobre o Ativo” (ROA). Foram determinadas as variáveis estatísticas (médias, medianas e coeficientes de variação) e posteriormente foi avaliada a hipótese de haver alguma mudança no valor médio do ROA após o ingresso da empresa no ISE através do teste de hipóteses não paramétrico de Mann-Whitney. Os resultados demonstraram que não há possibilidade de afirmar que a entrada no ISE irá ocasionar alguma mudança na rentabilidade da empresa, porém, a maioria das empresas apresentou uma melhora significativa na variabilidade da rentabilidade após o ingresso no ISE, ou seja, uma rentabilidade mais consistente.
Perspectives of rural farmer households on food security through a qualitative study in Indonesia
Authors:   Universitas Cahaya Prima, Yusriadi Y , Junus D ,   Universitas Gorontalo, Wijayanti R ,   STKIP PGRI Bangkalan, Hasnawati H ,   Universitas Cahaya Prima, Cahaya A ,   Universitas Cahaya Prima
Published: February 2024

In developing countries, rural farmers contribute significantly to food production, but their households are still vulnerable to poverty, food insecurity, malnutrition, and stunting. Although quantitative studies have explored the factors that influence farmers' dietary diversity, the data can be improved by integrating farmers' experiences and perspectives on whether and how these factors affect their dietary diversity. Malnutrition and food insecurity are more prevalent in developing and underdeveloped nations like Africa and Southeast Asia. Due to increased work, this country usually sees a rise in stunting, malnutrition, and increased physical activity. Stunting has a higher prevalence than other nutritional disorders, such as malnutrition, according to Nutrition Status Monitoring (NSM) data over the last three years. The frequency of stunting in children under five has risen from 27% in 2016 to 29% in 2017. This will assist in designing and implementing interventions. Forty rural farmers in Bone Regency, Indonesia, became informants in targeted interviews as part of the qualitative study (20 male and 20 female farmers). According to the research results, both male and female informants were concerned about the availability and variety of food. They feel that household food production is essential to achieve food security. Food sales are affected by prices, household income, distance to markets, and the range of food available. Household food production, knowledge, nutrition, availability, use of information, time, and household income are significant determinants of the variety of food consumed. In farming households, gender influences and variations on the distribution and use of food collected and income are explored. Men have more time to engage in agricultural endeavors that promote dietary diversity. Based on these findings, efforts to increase dietary diversity should address current food security and production challenges, support increased farm incomes and market access, utilize designs that address gender issues, and include nutrition capacity building, diverse practices, and social behavior change strategies. Key words: rural farmers, food security, food diversity, nutrition, market access, Indonesia
Wizyta z zaświatów: o przedstawieniach Swifta w dramacie Williama Butlera Yeatsa The Words upon the Window-Pane
Authors: Zirzotti Emanuela
Published: February 2024

W artykule podjęta została próba analizy dramatu W.B. Yeatsa The Words upon the Window Pane (1930), w którym irlandzki pisarz i poeta prezentuje własną interpretację postaci Jonathana Swifta oraz relacji z dwoma najważniejszymi towarzyszkami jego życia. Autorka przedstawia dziekana katedry Św. Patryka w Dublinie jako figurę literacką, ukształtowaną na potrzeby tego dramatu przez Yeatsa. Za pośrednictwem tak wymyślonej maski, czy też alter ego, Yeats oddaje własne doświadczenie starości oraz twórczego i osobistego niespełnienia. Zarówno postać Swifta, jak i Yeatsa wpisane zostają w rozważania na temat cielesnej i duchowej ascezy oraz powiązane z problematyką seksualności, cielesności i pożądania. Autorka stawia tezę, iż właśnie ta sztuka stanowi punkt zwrotny w późnej twórczości Yeatsa, w której szczególną uwagę poświęca się doświadczeniu nadprzyrodzonemu oraz sposobom ukazywania motywów zaczerpniętych z irlandzkiej tradycji literackiej za pośrednictwem realistycznej formy nawiązującej do pisarstwa Ibsena.
Machine Learning Algorithms for Early Detection of Legume Crop Disease
Authors: Cho Ok-Hue
Published: February 2024

Background: Legume crops are an essential component of global agriculture and are widely supplied for human consumption, livestock feed and soil improvement due to their vital nutritional nature. The economic and nutritional significance of legumes is threatened by a multitude of diseases that can cause substantial yield losses. Traditional methods for disease detection, relying on visual inspection, are often subjective and inefficient, leading to delayed intervention. Methods: This study investigates the utilization of machine learning algorithms for the early identification of diseases affecting legume crops. A comprehensive evaluation is conducted on machine learning algorithms, namely Support Vector Machines (SVM) and Convolutional Neural Networks (CNN) with respect to the domain of disease detection. Through a comparative analysis of their performance across different environmental conditions and phases of crop development, this study also explores their strengths and weaknesses. Result: The findings and comparative examination offered significant perspectives on the potential of machine learning algorithms in the realm of early legume crop disease detection. In addition to enhancing crop health and disease management, the research provides support for sustainable agricultural practices and possesses the capacity to augment environmental sustainability and food security through the application of machine learning techniques.
Didácticas generosensitivas: pistas para prevenir las violencias basadas en género desde la universidad
Authors: Florián Buitrago Maribel , Carreño Manosalva Clara Inés , Bueno Ana Marcela , Sánchez Corrales Natalia , Jiménez Pinzón Andrea Mireya , Vélez Villafañe Gerardo , Ascuntar Henao Andrea
Published: February 2024

La presente cartilla es producto de un proceso de investigación que tuvo como objetivo aportar en la prevención de las violencias de género en la Universidad de La Salle, mediante la problematización de las representaciones sociales que las y los estudiantes tienen sobre el amor y la sexualidad. Dicha problematización es importante por cuanto se trata de experiencias que tienen un lugar privilegiado en la construcción del lazo social. El amor y la sexualidad han sido correlatos que, en el proyecto del amor romántico, generan y mantienen las desigualdades entre los géneros.
An extensive investigation of the anthropometric measurements in males with 47,XXY (Klinefelter Syndrome) from birth to five years of age and the impact of early hormonal treatment (EHT)
Authors: Schmidt Kara , Gropman Andrea , Sadeghin Teresa , Jackson Toreh Alysandra , Samango-Sprouse Carole
Published: February 2024

Aim: 47,XXY (KS) is the most frequently occurring sex chromosome aneuploidy (SCA) with an incidence rate of 1:500 to 1:650 live male births. 47,XXY is characterized by androgen insufficiency and hypogonadism, diminished phallus size, hypotonia, and increased stature. This investigation examines the relationship between Early Hormonal Treatment (EHT) and growth in boys with 47,XXY from birth to 5 years.

Methods: A cohort of 134 males with 47,XXY was seen as part of a natural history study and anthropometric measurements were completed at each evaluation for height (HGT), weight (WGT), and head circumference (HC). Data was analyzed for these factors in the group receiving testosterone as EHT (T group) and a no treatment (No-T) control group.

Results: Significant differences in HC were observed between the T group and No-T group for birth to 12 months. There was no other significant difference in HC for boys between the ages of 13 to 60 months. Only significant differences were observed in the birth to 12 months group for HGT between the T group and No-T group. There were only significant differences in WGT in the birth to 12-month age range between the T group and the No-T group, as well as in the 12-24-month age range.

Conclusion: EHT is not associated with reducing or advancing growth in children with 47,XXY over 2 years old. After 24 months of age there is no discernible difference between boys with 47,XXY with EHT and without EHT.
A test-tube vinification method for high-throughput characterisation of the oenological and aromatic potential of white wines
Authors: Claudel Patricia , Dumas Vincent , Thibon Cécile , Lemarquis Grégory , Jaegli Nathalie , Sivsivadzé Ana , Baltenweck Raymonde , Hugueney Philippe , Duchêne Éric
Published: February 2024

The quality of wine largely depends on aroma perception, but the genetic basis explaining the variations of aroma compound concentrations in wines is still fragmentary. To unravel links between genetic variations and aroma compound variations in hundreds of genotypes, we developed a small-scale, high-throughput test-tube vinification (TTV) method capable of producing white wines that reveal the genetic potential at the scale of a single vine stock. We evaluated this method on commercial grapevine varieties (Riesling, Gewurztraminer, Chardonnay, Chasselas, Floreal, Muscat à petits grains blancs) and genotypes resulting from a bi-parental cross, covering a wide aromatic palette. The wines produced were described by usual oenological parameters and GC-MS profiling of volatile compounds. We compared the wines obtained with the TTV method to commercial wines and to wines obtained from larger fermentation volumes (5–10 L). Our results show that the TTV method is suitable to produce white wines on a very small scale, i.e., less than 100 mL and that these small-scale wines faithfully reflect the aromatic potential of the different varieties, as would larger volume methods. The proposed method is a high-throughput approach to assess the oenological potential of hundreds of grapevine genotypes from grape material harvested on a single vine. This wine-focused direct phenotyping method will pave the way for a better understanding of the genetic determinism of wine aromas, especially for molecules that are not directly present in grapes, such as volatile thiols and 1,1,6-trimethyl-1,2-dihydronaphthalene (TDN).
Pengaruh Model Guided Discovery Learning dengan Pendekatan Pendidikan Matematika Realistik Indonesia terhadap Kemampuan Berpikir Kreatif Siswa SMPN 12 Bekasi
Authors: Sari Lingga Buana Yunan , Salsabila Ellis , Hermin Fariani
Published: February 2024

Tujuan dari penelitian ini adalah mengetahui pengaruh model pembelajaran guided discovery learning dengan pendekatan pendidikan matematika realistik Indonesia terhadap kemampuan berpikir kreatif siswa. Metode penelitian ini adalah metode quasi-experiment dengan posttest only control group design. Teknik pengambilan sampel menggunakan cluster random sampling sehingga sampel yang diperoleh adalah kelas VII.A dan VII.C. Teknik pengumpulan data menggunakan tes uraian kemampuan berpikir kreatif siswa. Analisis data dilakukan sebanyak 2 kali, yaitu sebelum dan sesudah penelitian dilakukan. Berdasarkan hasil pengujian hipotesis menggunakan uji-t dengan taraf signifikansi α = 0.05 menunjukkan bahwa rata-rata kemampuan berpikir kreatif siswa pada kelas eksperimen lebih tinggi dibandingkan rata-rata kemampuan berpikir kreatif siswa pada kelas kontrol. Nilai besar pengaruh dengan Cohen’s effect size menunjukkan persentase 66%. Berdasarkan hasil penelitian, maka dapat disimpulkan bahwa terdapat pengaruh dari penerapan model guided discovery learning dengan pendekatan pendidikan matematika realistik Indonesia terhadap kemampuan berpikir kreatif siswa SMP Negeri 12 Bekasi.
Type III Popliteal Artery Entrapment Syndrome with Concurrent Chronic Exertional Compartment Syndrome
Authors: Armando Chenée , Sherbondy Paul , Simoni Eugene , Cole Sandra
Published: February 2024

Case:

The patient, a 21-year-old female Division I track and field athlete, presents with bilateral calf pain, tightness, numbness, and swelling during activity. Initially diagnosed with chronic exertional compartment syndrome (CECS), she underwent bilateral four-compartment fasciotomies. After 4 months, she experienced persistence of some of her prefasciotomy symptoms and was referred to vascular surgery. A fibrous band was compressing the popliteal artery, making the diagnosis of popliteal artery entrapment syndrome (PAES). She underwent bilateral popliteal artery decompressions. She had a successful recovery with no recurrence of numbness, weakness, or pain.

Conclusion:

Recognize that structural PAES may coexist with CECS.
The Effects of Environmental Noise on Annoyance, Stress, and Urine Cortisol Levels Among Residents Living Near Industrial Sites in Bangkok, Thailand
Authors: Onmek Nutthajit , Bordeerat Narisa Kengtrong , Wangwongwatana Supat
Published: February 2024

People are exposed to environmental noise each day. It may be annoying, cause stress, induce hormonal changes, and negatively affect long-term health. This study aimed to determine the effects of environmental noise on annoyance, perceived stress, stress symptoms, and urine cortisol in people living in a selected area. This cross-sectional study was conducted from April to October 2022 on 142 participants. Urine samples were collected to determine cortisol levels, and perceived stress, stress symptoms, and environmental noise annoyance were evaluated using questionnaires. Stress symptoms correlated with traffic, industrial, and community noise, but not aircraft noise. Community noise correlated most strongly with all stress symptoms. Only community noise exposure was correlated with perceived stress. People reported that industrial and community noise affected their health and daily activities. Cortisol correlated with only traffic noise annoyance. Environmental noise was associated with stress symptoms and stress hormones. In brief, sound level is not the onlyindicator of stress or health impacts, but annoyance and concern over the effects of noise may negatively affect stress and health.
Daily Income Targets and Passenger Pressure on Safety Risky Riding Behavior Among Online Motorcycle Taxi Riders in Jakarta, Indonesia
Authors: Djunaidi Zulkifli , Khaliwa Agra Mohamad , Hafia Azka , Putri Nadya
Published: February 2024

Online motorcycle taxi riders, a vulnerable group on the road, are more susceptible to serious injury than non-motorcycle riders. This study analyzed a correlation between daily income targets, passenger pressure, risk perception, safety attitudes, and risky riding behavior. This cross-sectional study used a semi-quantitative approach by collecting online-based questionnaires from 500 online motorcycle taxi riders in Jakarta, and 50 of them were obtained through offline interviews. The findings revealed a significant relationship between daily income targets, passenger pressure, risk perception (danger level, stochastic evaluation, and safety priority), safety attitudes (pragmatic attitude to rule violations and dissatisfaction with traffic rules), and risky riding behavior, with a p-value of <0.05. In particular, a pragmatic attitude to rule violations was the most impactful on risky riding behavior. Online motorcycle taxi companies should provide regular training on traffic laws and safe riding practices to improve road safety. This holistic approach may enhance safety through education, passenger awareness, and rigorous management.
Sources of Ore Material in the Platinum-Group Element Deposits of Polar Siberia and the Middle Urals Based on the Data from Radiogenic (Re–Os, Pt–Os) and Stable (Cu, S) Isotopes
Authors: Malitch K.N. , Puchtel I.S. , Badanina I.Yu. , Votyakov S.L. , Soloshenko N.G. , Belousova E.A. , Velivetskaya T.A. , Ignatiev A.V.
Published: February 2024

—Understanding the main events of platinum-group element (PGE) ore formation is impossible without analysis of the sources and behavior of major ore-forming components, namely, platinum, osmium, sulfur, and copper, which are important indicators of magmatic and hydrothermal processes. In contrast to the Re–Os isotope system, the radiogenic Pt–Os isotope system, as well as stable isotopes of Cu and S in PGE deposits, are still relatively understudied. Our comprehensive research is aimed at filling this gap. The paper presents data for the Guli massif of ultramafic and alkaline rocks and carbonatites in Polar Siberia and on the zonal Nizhny Tagil and Svetly Bor clinopyroxenite–dunite massifs in the Middle Urals, which include: (1) the contents of the highly siderophile elements (HSE) in whole rocks and platinum-group minerals (PGM), (2) the Re–Os and Pt–Os isotope systematics of chromitite, Os–Ir alloys, and Ru–Os sulfides, (3) the sulfur isotope composition in Ru–Os and Ir–Rh sulfides in primary and secondary PGM assemblages, and (4) the copper isotope composition in Pt–Fe minerals from chromitites and placers. The research was performed using scanning electron microscopy, electron probe microanalysis, and high-precision isotope-geochemical analysis. The high-precision Re–Os and Pt–Os isotope data show that the HSE contents in chromitites and PGM of the Guli massif were controlled by the composition of the mantle source that evolved with near-chondritic time-integrated Re/Os and Pt/Os ratios, which are also typical of the sources of most komatiites and abyssal peridotites. The δ65Cu values of the studied samples of ferroan platinum and isoferroplatinum are identical within the analytical uncertainty and are close to 0‰, which is typical of high-temperature Cu-containing minerals. The sulfur isotope compositions of the Ir–Rh sulfides of the kashinite–bowieite series and of the Ru–Os sulfides of the laurite–erlichmanite series in the primary PGM assemblages indicate that the source of sulfur has a chondritic isotope composition, which is in agreement with the osmium isotope composition of the Ru–Os sulfides and Os–Ir alloys. The heavy sulfur isotope composition (δ34S = 5.6 ± 1.5‰) of As-containing erlichmanite is consistent with its secondary origin. The new data on the isotope compositions of osmium, copper, and sulfur can be used as new important parameters that characterize the sources of PGE mineralization.
“A voz da América Latina”: a emergência do epíteto sobre Mercedes Sosa e sua retomada póstuma
Authors: Souza Nathan Bastos de
Published: February 2024

O objetivo deste texto é estudar o epíteto “a voz da América Latina” em dois momentos: durante e depois da vida de Mercedes Sosa. Nessa perspectiva, primeiramente compreendemos a emergência do epíteto nos primeiros shows da cantora na Europa, na década de 1980, à luz da ideia de “apoio do coro”, de Bakhtin (2011). Em seguida, analisamos as paráfrases do epíteto presentes em obituários à luz da discussão sobre tema e significação, de Volóchinov (2017). Os resultados apontam para a) a emergência do epíteto de natureza comercial, que causa efeitos de sentido políticos supostamente não esperados, e sua ancoragem no apoio do coro; b) que as formas diferentes de retomada do epíteto sempre redundam em características edificantes que remetem à grandeza da cantora argentina, como voz que canta e voz que fala.
Groundwater suitability assessment for irrigation and drinking purposes by integrating spatial analysis, machine learning, water quality index, health risk model
Authors: Yan Yuting , Zhang Yunhui , Yao Rongwen , Wei Changli , Luo Ming , Yang Chang , Chen Si , Huang Xun
Published: February 2024

An in-depth understanding of nitrate-contaminated groundwater quality and risks is important for groundwater management. Hydrochemical characteristics and driving forces of groundwater quality and non-carcinogenic risks of nitrate were revealed by the integrated approaches of self-organizing map analysis, spatial visualization by geography information system, entropy and irrigation water quality indices and human health risk model. Groundwater samples were subdivided into two clusters by SOM analysis. Cluster Ⅰ including three samples were Ca-SO4 type and cluster Ⅱ of remaining 136 samples were Ca-HCO3 type. Hydrochemical compositions of two cluster samples were dominated by water-rock interaction: (1) calcite and gypsum dissolution for Cluster I samples, and (2) calcite dissolution, silicate weathering and positive cation exchange for Cluster Ⅱ samples. Nitrate contamination occurred in both Cluster I and Ⅱ samples, primarily induced by agricultural nitrogen fertilizer. The EWQI results showed that 90.97% in total groundwater samples were suitable for drinking purpose, while the IWQI results demonstrated that 65.03% in total groundwater samples were appropriate for irrigation purpose. The HHR model and Monte Carlo simulation indicated that the non-carcinogenic nitrated risk was highest in children. Exposure frequency was the most sensitive factor (86.33% in total) influencing the total non-carcinogenic risk, indicated by sensitivity analysis.
A soft cable loop based gripper for robotic automation of Chemistry
Authors: Manes Lupo , Fichera Sebastiano , Fakhruldeen Hatem , Cooper Andrew , Paoletti Paolo
Published: February 2024

Robotic automation is proving itself indispensable in the modern Chemistry laboratory, but adoption is slowed down by the technical challenges of implementing such systems. This paper reports on a novel adaptive gripper mechanism that can easily and reliably grasp cylindrical and prismatic objects of various sizes with limited clearance required. The proposed design exploits the inherent compliance of a cable that is driven to fully envelope the target object. The cable is run through a rigid finger, allowing the loop to be placed around objects with minimal clearance required and to provide support for the object once the grip is complete. Thanks to the compliant nature of the mechanism, the gripper requires minimal control effort to complete a gasping task. A prototype of the gripper has been designed and built for chemistry automation tasks, where it showed very high grasp reliability with $\leq 0.1\%$ grasp failures.
Increasing contribution of the atmospheric vertical motion to precipitation in a warming climate
Authors: Jun Tackseung , Rind David
Published: February 2024

Global warming is already influencing precipitation worldwide, with more intense amounts being recorded in many locations. Although projections of changes in mean precipitation show a tendency for the ‘wet-get-wetter, dry-get-drier’ in many locations, the situations for precipitation extremes and specific regions are more complex, due to changes in dynamic and thermodynamic influences on atmospheric moisture distributions. Here, we build a dynamically interactive model of atmospheric moisture for the present (2006-2025) and the future climate (2081-2100), informed by outputs from coupled ocean-atmosphere general circulation models to investigate the precise processes that influence the daily precipitation around the world. We find that the dynamic process of vertical advection of the atmosphere, augmented by the horizontal convergence of moisture on the previous day, dominates the same-day precipitation, while the smaller impact of the thermodynamic process provides convective available potential energy for several days. As climate warms, we find that (i) the dynamical-induced precipitation more completely exhausts the vertically-integrated moisture in the models, which results in heavier rainfall. This reduces the thermodynamic influence and horizontal moisture advection after the precipitation; (ii) the distribution of impacts of the dynamic process on precipitation exhibits a greater spread in the warmer future, leading to more frequent extreme precipitation. The findings imply that the contribution of the atmospheric vertical motion in heavy rainfall increases as climate warms. Our results demonstrate that identifying the precise role and interactions among dynamic and thermodynamic processes is crucial for resolving the differentiated future precipitation responses to global warming.
Predictors for Temporary Stomas Non-Closure among Non-Metastatic Rectal Cancer Patients Undergoing Curative Resection: a Retrospective Analysis
Authors: Hsu Chia-Chien , Tsai Wen-Sy , Tsai Tzong-yun , You Jeng-Fu , Yeh Chien-Yuh , Hsieh Pao-Shiu , Tang Reiping , Huang Shu-Huan
Published: February 2024

Background:
The primary treatment for non-metastatic rectal cancer is curative resection. However, sphincter-preserving surgery may lead to complications. This study aims to develop a predictive model for stoma non-closure in rectal cancer patients who underwent curative-intent restorative proctectomy surgery.
Methods:
Consecutive patients diagnosed with non-metastatic rectal cancer between January 2005 and December 2017, who underwent proctectomy, were retrospectively included in the Chang Gung Memorial Foundation Institutional Review Board. A comprehensive evaluation and analysis of potential risk factors linked to stoma non-closure were performed.
Results:
Out of 956 patients with temporary stomas, 10.3% (n = 103) experienced non-closure primarily due to cancer recurrence and anastomosis-related issues. Through multivariate analysis, several preoperative risk factors significantly associated with stoma non-closure were identified, including advanced age, anastomotic leakage, positive nodal status, high preoperative CEA levels, lower rectal cancer presence, margin involvement, and an eGFR below 30 mL/min/1.73m2. A risk assessment model achieved an AUC of 0.724, with a cutoff of 2.5, 84.5% sensitivity, and 51.4% specificity. Importantly, the non-closure rate could rise to 16.6% when more than two risk factors were present, starkly contrasting the 3.7% non-closure rate observed in cases with a risk score of 2 or below (p < 0.001).
Conclusion:
Prognostic risk factors associated with the non-closure of a temporary stoma include advanced age, symptomatic anastomotic leakage, nodal status, high CEA levels, margin involvement, and an eGFR below 30 mL/min/1.73m2. Hence, it is crucial for surgeons to evaluate these factors and provide patients with a comprehensive prognosis before undergoing surgical intervention.