bluuebunny/crossref_metadata_2025 huggingface dataset:
A TRANSFORMAÇÃO EDUCATIVA EM CASCAVEL - PR: UMA ANÁLISE DA INSTITUCIONALIZAÇÃO E IMPLEMENTAÇÃO DA PEDAGOGIA HISTÓRICO-CRÍTICA
Authors: Albuquerque Andreia Iara Carvalho Piovesan , Tureck Lucia Terezinha Zanato
Published: February 2024

Este artigo busca apresentar uma análise da institucionalização e da implementação da Pedagogia Histórico-Crítica (PHC) em Cascavel, Paraná, Brasil, a partir de uma revisão de literatura. Utilizando o método do materialismo histórico-dialético para análise e interpretação, o estudo destaca a necessidade de transformar a escola em uma instituição histórica. Ressalta-se se a importância da colaboração e a compreensão crítica da sociedade, da história e conhecimento. O estudo enfatiza uma abordagem colaborativa e um compromisso autêntico com uma educação verdadeiramente transformadora. Evidencia-se que essa transformação é essencial para capacitar os educadores a implementar efetivamente esses princípios, na prática, garantindo uma educação emancipatória as futuras gerações, contribuindo para o aprimoramento contínuo do sistema educacional, promovendo, uma sociedade mais justa e igualitária.
Aproximações da Fenomenologia Social aos conceitos de Mikhail Bakhtin
Authors: Vasconcelos Simone Oliveira Thompson de , Nascimento Crisóstomo Lima do , Lima Jacqueline de Cássia Pinheiro
Published: February 2024

A investigação apresentada é um ensaio teórico da tese de doutorado “Retratos sociais da cidade e a formação inicial de professores: propostas formativas a partir das aproximações da fenomenologia social aos conceitos de Bakhtin” do Programa de Cognição e Linguagem, da Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF). Este recorte possui como objetivo principal apresentar as aproximações entre a filosofia de Alfred Schutz (Fenomenologia Social) e a de Mikhail Bakhtin (Linguagem Dialógica). Para alcançar o objetivo colocamos em perspectiva, por meio de pesquisa bibliográfica, as concepções esboçadas nos fundamentos filosóficos de suas obras, particularmente Estética da Criação Verbal (BAKHTIN, 1997), Problemas na poética de Dostoieviski (BAKHTIN, 2013), Por uma filosofia do ato responsável (BAKHTIN, 1993), o conjunto de textos que compõem a teoria do romance de Bakhtin, Fenomenologia e relações sociais (SCHUTZ, 1970) e A fenomenologia do mundo social (SCHUTZ, 1967) de Alfred Schutz. A tese se insere na problemática da formação de professores/mediadores. Para realizar a pesquisa apresentaremos propostas formativas utilizando espaços da cidade, a partir das reflexões propostas pela fenomenologia social de Schutz e dos conceitos de Bakhtin, visando contribuir para a formação de professores/mediadores ampliando sua leitura de mundo e a práxis pedagógica. Para tanto refletiremos sobre a formação do ser/sujeito/estudante por meio de contextos filosófico, histórico, político e social. Assim, neste artigo, além das aproximações entre os autores supracitados e alguns de seus conceitos, faz-se um relato sobre a importância da filosofia para a educação escolar e pontes com a pedagogia progressista. Utilizamos como metodologia a pesquisa qualitativa a partir do eixo teórico-metodológico fenomenológico, concluindo a existência de diálogos possíveis entre os pensamentos dos autores, apesar das formações e histórias de vida distintas.
Expectativa e realidade: efeitos de uma intervenção pedagógica com estratégias autorregulatórias de atividade física
Authors: Gouvêa Bruno dos Santos , Dias Bruno Rodrigues , Jesus Simone Emiliano de , Silva Kátia Regina Xavier da , Amadeu Thaís Porto
Published: February 2024

Neste estudo, recorte de uma pesquisa de Doutorado, objetivou-se mapear os efeitos de uma intervenção pedagógica on-line ancorada em estratégias autorregulatórias de atividade física (AF) durante a pandemia em um colégio público. Trata-se de uma pesquisa qualitativa, do tipo intervenção pedagógica com auxílio de recurso didático. Foram realizadas 8 entrevistas semiestruturadas em grupo on-line com 35 estudantes (14 a 17 anos) do Ensino Médio. Utilizou-se o software IRaMuTeQ para interpretar os dados. Os resultados foram organizados em seis classes: “Diário como estímulo para AF”, “Estratégias para aumentar a motivação”, “Escolhas e fatores socioestruturais para AF”, “Influência do gosto e do incentivo para AF”, “Reflexões sobre metas e autoavaliação”, “Monitoramento da AF”. Estudantes previamente inativos ou pouco ativos (identificados com o personagem do recurso didático) sentiram-se mais confiantes para praticar AF (efeito positivo) com estratégias ensinadas na intervenção (diário de AF). Estudantes ativos fisicamente atribuíram efeito neutro à intervenção, mas valorizaram as reflexões críticas sobre as desigualdades sociais e a AF. Alguns estudantes empregaram estratégias autorregulatórias simples (metas graduais) mais consistentemente durante a intervenção, enquanto outros não as empregaram por: não ser algo intuitivo; falta de motivação; esquecimento. A intervenção pedagógica parece ser eficaz para o ensino conceitual das interfaces entre AF, psicologia e sociedade.
Platinum Group Metals in the Potential Limitation of Tobacco Related Diseases
Authors: Boyd David
Published: February 2024

In recent years there has been increased interest in the tobacco industry driven primarily by high-profile disclosures made during health-related litigation in the United States of America. Over the years, tobacco companies and others have filed many patents aimed at reducing the concentrations of known harmful chemicals in tobacco smoke. The literature contains a number of articles and patents which mention the potential for platinum group metals to decrease these harmful effects. This review attempts to summarise the published work in which the platinum group metals have been discussed with respect to cigarette use.
Improvements to the Microstructure and Physical Properties of Pd-Cu-Ag Alloys
Authors: Volkov A. Yu.
Published: February 2024

Ordering and decomposition kinetics of Pd-Cu-Ag alloys having the B2-type superstructure that contain 0 to 30 wt.% silver have been studied. The results of investigations into the microstructure, electrical and mechanical properties are described. Different methods for improving the strength properties of ordered alloys are discussed.
Piezochromism and Related Phenomena Exhibited by Palladium Complexes
Authors: Takagi Hideo D. , Noda Kyoko , Itoh Sumitaka , Iwatsuki Satoshi
Published: February 2024

Piezochromic phenomena are explained by pressure perturbation to the HOMO and/or LUMO energy levels of the related electronic transition. The piezochromism of solid inorganic and organic materials has been investigated by examination of the phase transition phenomena. Specific electronic properties of the solids, acquired by tuning the external pressure, may be used as electronic devices and as pressure sensors. The effects of pressure perturbations on the absorption and emission spectra exhibited by solid palladium complexes are reviewed here. Related phenomena exhibited by platinum complexes and other metal complexes are included for comparison.
A Platinum Resistance Thermometer for High Temperatures
Authors: Obrowski W.
Published: February 2024

A new type of platinum resistance thermometer, constructed with ceramic insulating materials, is described. It may be maintained in continuous operation at temperatures up to 850°C for many hundreds of hours.
The First Experiments on Platinum
Authors: Russell-Wood J.
Published: February 2024

Upon the whole, this Semi metal feems a very Angular Body, that merits an exacter Inquiry into its Nature than hath hitherto been made; fince it is not altogether improbable, that, like the Magnet, Iron, Antimony, Mercury, and other metallic Substances, it may be endowed with fome peculiar Qualities, that may render it of fingular Use and Importance to Mankind.
The Early History of the Thermocouple
Authors: Hunt L.B.
Published: February 2024

The name of Seebeck is indissolubly associated with the discovery of thermoelectricity and the thermocouple. But how did Seebeck’s researches fit into the general background of contemporary scientific work, and how did they lead on to the development of the modern thermocouple pyrometer? This article outlines the early history of the couple up to the time when it became accepted as an accurate and reliable means of measuring high temperatures.
Prevention of Corrosion in Paper Making Machines
Authors: Almar-Naess A. , Drugli J. M.
Published: February 2024

Corrosion problems can become severe in paper-making machines in which the pulp is dried over steam-heated castiron cylinders. Paper with a smooth bright surface will be produced provided that the cylinder remains smooth and bright, but corrosive media in the pulp attack the surface. This article describes the successful application of cathodic polarisation, using platinum-titanium anodes, to a large paper-drying cylinder to give it complete protection from corrosion
International Congress on Catalysis
Authors: B.H.
Published: February 2024

At four yearly intervals the International Congress on Catalysis provides an opportunity to identify the major areas of growth and importance in catalysis, particularly where the noble metals are involved. This article reviews some of the many papers on catalysis by the platinum metals that were presented at the latest congress.
Catalytic Aspects of Some Phosphine Complexes of the Platinum Metals
Authors: Hartley F. R.
Published: February 2024

The 1980 Biennial Symposium jointly organised by the Inorganic Divisions of the Canadian Institute of Chemistry and the American Chemical Society, held in Guelph, Ontario, from the 5th to 7th June, was entitled “Catalytic Aspects of Metal Phosphine Complexes”. This article concentrates on the contributions presented there that were particularly concerned with the platinum group metals.
Liquid Fuels from Coal
Authors: Everson R. C. , Thompson D. T.
Published: February 2024

It is now possible by selecting appropriate reaction conditions to use ruthenium on alumina catalysts to produce economically viable ranges of gasoline and diesel fractions from the synthesis gas produced by coal gasification. Recent work has shown that simultaneous use of ruthenium with an intermediate pore zeolite produces high octane gasoline. The activity and selectivity achievable with ruthenium are compared and contrasted with results from systems based on iron and cobalt catalysts which have already achieved commercial significance.
An Early Industrial Application for Malleable Platinum
Authors: Cottington Ian E.
Published: February 2024

For a period in the early nineteenth century, when malleable platinum was first available commercially, the high temperature and corrosion resistant properties of the metal were utilised for the manufacture of the touch-holes and pans of flintlock pistols, guns and rifles by English gunmakers, who also used it for some simple decorative purposes. Advances in firearms technology resulted in the effective disappearance of this application round about 1820, although by then platinum was used in various forms of percussion gun. This article considers some aspects of the flintlock use, including the claim made by Joseph Manton that he was the inventor of platinum touch-holes.
Henri Sainte-Claire Deville
Authors: Chaston J. C.
Published: February 2024

The centenary of the death of Henri Sainte-Claire Deville, teacher, chemist and technologist, is a reminder of the quite exceptional part he played in laying the foundations of the modern platinum industry.
Platinum Metals in Ohmic Contacts to III-V Semiconductors
Authors: Ivey D. G.
Published: February 2024

Platinum metals, particularly platinum and palladium, are used extensively in low resistance, relatively stable and laterally uniform ohmic contacts made to semiconductor devices formed from Group III and V elements. Palladium is primarily utilised as one component of a multilayer metallisation
structure, improving adhesion to the semiconductor, while platinum is commonly used as a diffusion barrier to minimise interdiffusion between metal and semiconductor components. This paper describes the roles of platinum and palladium in ohmic contacts, gives examples of their typical utilisation
and outlines the design considerations associated with the formation of reliable ohmic contacts.
The Oxidation of Alcohols to Aldehydes or Ketones
Authors: Friedrich Holger B.
Published: February 2024

The oxidations of alcohols to aldehydes and ketones are vital reactions in synthetic organic chemistry, and high selectivity and mild conditions are important prerequisites for ease of product work-up and lower cost. Currently, many of the best oxidants for these conversions contain
high valent ruthenium, with ruthenium acting as a catalyst for these reactions. It is important to have detailed knowledge and understanding of the mechanisms of the oxidation reactions and the factors that influence them, as only by completely understanding how these processes work will it
be possible to design better or optimal catalysts. In this paper, the more viable oxidants currently available are reported and some investigations into the mechanisms of the reactions and factors affecting them are discussed.
The Heck Reaction and Cinnamic Acid Synthesis by Heterogeneous Catalysis
Authors: Wall Valerie M. , Eisenstadt Amihai , Ager David J. , Laneman Scott A.
Published: February 2024

The Heck reaction for the construction of carbon-carbon bonds, using palladium catalysts, is one of the most valuable strategies in organic chemistry and appears frequently in the literature, usually as homogeneous catalysis. In this review the progress made to date with this reaction
is examined, together with the most discussed aspects of the Heck reaction, including a description of its mechanism and the conditions required for success. Some limitations to the homogeneous reaction are mentioned with reasons for proceeding with heterogeneous catalysts, in particular with
palladium/carbon. Examples of various heterogeneous Heck reactions are presented and work that we are undertaking to develop methods for the production of cinnamic acids, useful as substrates for the synthesis of “unnatural” amino acids, is discussed. Finally, we present some results
from our work using palladium/carbon catalysts for heterogeneous Heck reactions.
NONLINEAR EFFECTS IN VISCOELASTIC DROP SHAPE OSCILLATIONS
Authors: Zrnic Dino , Brenn Günter
Published: February 2024

A study of axisymmetric shape oscillations of viscoelastic drops in a vacuum is conducted, using the method of weakly nonlinear analysis. The motivation is the relevance of the shape oscillations for transport processes across the drop surface, as well as fundamental interest. The study is performed for, but not limited to, the two-lobed mode of initial drop deformation. The Oldroyd-B model is used for characterizing the liquid rheological behavior. The method applied yields a set of governing equations, as well as boundary and initial conditions, for different orders of approximation. In the present paper, the equations and solutions up to second order are presented, together with the characteristic equation for the viscoelastic drop. The characteristic equation has an infinite number of roots, which determine the time dependency of the oscillations. Solutions of the characteristic equation are validated against experiments on acoustically levitated individual viscoelastic aqueous polymer solution drops. Experimental data consist of decay rate and oscillation frequency of free damped drop shape oscillations. With these data, solutions of the characteristic equation dominating the oscillations are identified. The theoretical analysis reveals nonlinear effects, such as the excess time in the prolate shape and frequency change for varying initial deformation amplitude. The influences of elasticity, measured by the stress relaxation and deformation retardation time scales, are quantified, and the effects are compared to the Newtonian case in the moderate-amplitude regime.
The Early Concept of the Celtic Colour Term glas in Welsh and Irish and its Later Semantic Diversification
Authors: Asmus Sabine , Ó Fionnáin Mark
Published: February 2024

The Celtic colour term glas has been subject to a number of misconceptions over the decades, e.g.that it is a grue category, that it is untranslatable, and that the range of colour shades covered by glas is cross-linguistically rare. Coming from a diachronic perspective,
this article aims to give a logical explanation of the developments of the semantics of glas, followed by an overview of the synchronic semantics of the word in both Irish and Welsh.
Análisis de necesidades para un curso de variación lingüística dirigido a estudiantes de ELE
Authors: Algué-Sala Lluís
Published: February 2024

El presente estudio describe el proceso de elaboración de un análisis de necesidades para un curso de variación lingüística dirigido a estudiantes de cuarto curso de filología hispánica en una universidad china. Siguiendo el marco teórico de Brown (2009) para la elaboración de análisis de necesidades, se realiza una investigación empírica con cuestionarios a estudiantes y entrevistas a profesores para determinar el punto de partida de los participantes del curso, paso previo para el establecimiento de los objetivos que el grupo meta debería alcanzar tras cursarlo. Entre los principales hallazgos se identifica la necesidad de impartir conocimientos sociolingüísticos básicos para minimizar la presencia de sesgos asociados con las percepciones del binomio lengua-dialecto en los países hispanohablantes y en China, la necesidad de impartir contenidos para enriquecer los conocimientos de las variedades del español más allá de los bloques España-Hispanoamérica y la implantación de pedagogías críticas en cuanto las dimensiones que la variación lingüística puede tomar tanto en la lengua meta como en la lengua materna.
Editorial
Authors: Huete-García Ángel , Nomdedeu-Rull Antoni
Published: February 2024

En un mundo globalizado en donde el español es una de las lenguas más estudiadas como LE/L2, este monográfico pretende acercar algunas de las cuestiones relativas a la variación lingüística en español mediante cuatro propuestas novedosas. En concreto, en este número especial monográfico de la Revista Internacional de Lenguas Extranjeras (RILE), cinco especialistas del ámbito abordan el tema de la variación lingüística desde una perspectiva aplicada a la enseñanza de lenguas. Todos los trabajos que conforman este monográfico se han llevado a cabo por investigadores e investigadoras internacionales que están desarrollando sus carreras en Colombia, China e Italia, y que cuentan con una sólida trayectoria profesional.
Prototipo «Dico Culturel» (Diccionario Cultural): evaluación de los contenidos culturales
Authors: Serrano-Carranza Olga Rocío
Published: February 2024

El proyecto «Dico Culturel» (Diccionario Cultural) consistió en concebir un modelo de diccionario cultural, bilingüe, unidireccional, francés de Francia-español de Colombia. Se escogieron 100 vocablos o expresiones de la lengua francesa y a partir de estos se redactaron los artículos que incorporan informaciones lingüísticas y sobre todo culturales e interculturales entre estos dos países. En este artículo, evaluamos el grado de pertinencia y la forma en la que se organizaron y se presentaron los contenidos culturales en el prototipo creado. A partir de una encuesta constituida de una serie de enunciados, interrogamos a un grupo de estudiantes universitarios de francés. Les solicitamos su opinión sobre los contenidos culturales de una muestra de artículos del diccionario. Los datos obtenidos fueron examinados cuantitativamente y nos permitieron constatar la valoración positiva del prototipo por los estudiantes. Por consiguiente, se concluye que este recurso puede contribuir ampliamente al aprendizaje del Francés Lengua Extranjera (FLE) y a la comprensión cultural e intercultural, ya que, a través de las informaciones suministradas, se genera una conciencia cultural. De esta manera, los estudiantes reflexionan y se sensibilizan acerca de los diversos contenidos culturales e interculturales que se cobijan en el léxico y sobre sus singularidades dependiendo de cada comunidad lingüística.
mobilidade e defesa entre o Estado do Grão-Pará e a capitania de Mato Grosso (1759-1772)
Authors: Vítor Vieira Ribeiro Otávio
Published: February 2024

Na Amazônia Portuguesa, os rios constituíram-se nas únicas estradas disponíveis para o deslocamento regional. As canoas de transporte confeccionadas e conduzidas pelos povos indígenas eram o suporte material empregado na comunicação entre as suas fronteiras. O vencimento dos rios Madeira, Mamoré e Guaporé articulou o trânsito de governadores e de tropas entre o Estado do Grão-Pará e a capitania de Mato Grosso. Sendo assim, este artigo parte do circuito interno da comunicação política dos governadores e capitães-generais do Estado do Grão-Pará e da capitania de Mato Grosso, para discutir o papel desempenhado pelos povos indígenas na mobilidade destes oficiais e no trânsito de tropas entre as suas repartições, de 1759 a 1772.
indígenas e o militarismo luso no Estado do Grão-Pará e Maranhão (1750-1778)
Authors: Alexandrino Viana Wania
Published: February 2024

Este artigo pretende analisar a presença indígena no militarismo luso do Estado do Grão-Pará e Maranhão (1750-1778). Esse contexto trouxe profundas transformações para os quadros do militarismo português, o qual também se ajustava às demandas coloniais. É objetivo deste trabalho não apenas compreender esse processo, mas sobretudo, as implicações da lei de Liberdade de 1755 e da Carta Régia 1766 no ajuste das forças defensivas do Estado que incluiu a presença indígena institucionalizada em tropas de milícias e ordenanças. Por meio da análise sistemática de diversas fontes pretende-se tornar evidente que essas mudanças deslocaram os indígenas das margens do militarismo à normatividade, que se faz ver nos registros de patentes e de tropas indígenas. Essa nova condição tornou-se, pela agência indígena, espaço nos quais esses sujeitos manifestavam seus próprios interesses e lutavam por suas demandas na sociedade amazônica colonial.
Fundamentos del Álgebra Universal
Authors: Rosado Velasco Álvaro Juan
Published: February 2024

En este ensayo se desarrollan las herramientas fundamentales con las que pueden construirse las formas generales y el entramado matemático del Universo, desde la Dimensión Cero hasta la Tercera Dimensión, pasando por todos los estados intermedios: punto, línea, cuadrado, elipse, círculo, esfera, etc. Estas herramientas se crean a partir de los operadores energéticos primarios; unas entidades operacionales matemáticas que constituyen la esencia misma del Álgebra Universal. En base a estos operadores algebraicos/funcionales, se determina, además, la función exacta del operador “pi” y se calcula de forma real la circunferencia, el área y el volumen de cualquier elipse.
COVID-19 and Mental Health in Ohio: Trends from 2017 to 2021
Authors: Roberts Megan E. , Crane Dushka , Elliott-Dorans Lauren , Price-Spratlen Townsand , Albani Thomas , Sahr Timothy R. , Singer Jill M. , Knudsen Kraig , Nau Michael , Tosun Leyla , Applegate Mary
Published: February 2024

Background: Mental health impairment (MHI) refers to a high threshold of mental health diagnosis, whereby individuals are unable to participate in work or other usual activities due to a mental health condition or emotional problem. This study aimed to estimate COVID-19-related trends and disparities in high MHI for Ohio adults throughout the COVID-19 pandemic. An additional goal was to identify modifiable factors associated with high MHI.Methods: Analyses were conducted using data from the 2017, 2019, and 2021 Ohio Medicaid Assessment Survey (OMAS). This a repeated, cross-sectional random probability survey of noninstitutionalized adults assessing the health of residential Ohioans, with a concentration on Ohio’s Medicaid, potentially Medicaid eligible, and non-Medicaid populations.Results: The prevalence of high MHI among Ohio adults rose between 2017 (6.4%) and 2021 (8.2%). This increase was particularly pronounced among Black and Hispanic individuals; 2021 also saw high MHI among young women. In adjusted analysis, indicators of low fiscal stability and having unmet health care needs were associated with greater prevalence of high MHI.Conclusion: Pandemic-related mental health trends and disparities extended to those at the highest levels of mental illness severity and treatment need. Several modifiable factors could be targeted to potentially improve mental health symptoms and to be better prepared for the next public health crisis.
Impact of COVID on the mental health and cognitive functioning level of elderly individuals
Authors: RM Nagalakshmi
Published: February 2024

Background: The unprecedented COVID-19 outbreak caused widespread worry and alarm throughout the world. The virus affected people of all ages, although the elderly is at a larger risk. This study examines the mental health concerns and the cognitive functioning that older people encounter as a result COVID affected. Objective: To study the mental health and cognitive functioning level in older adults with covid affect in comparison with non-covid affect. Methods: Comparative study design was adapted; participants include those who are aged above 60 years with covid affected and non-covid affected. Socio-demographic details were collected. Clinical scales such as GHQ, GDS and HARS were utilized for checking the mental health condition of the elderly individuals. MMSE scale was used for assessing the cognitive level. Results: The sample size consisted of 30 elderly individuals with 15 covid affect and 15 elderly with non-covid affected. The mean age of the covid affected group was 65.9 years and non-covid group was 65.8. Covid group scored low on orientation mean and SD (2.75±1.91), memory (1.75±1.40) and total MMSE (18.45±5.10) than compared non-covid affected. There is a significant difference between the covid and non-covid on orientation p=0.023* and total MMSE p=0.007** Discussion: The results revealed that covid affected scored lower on orientation, memory and total cognitive score than non-covid affected elderly individuals. Age and education has positive association with cognition level and general health had negative correlation with orientation indicates higher scores on GHQ lower in orientation.
Molecular biomarkers in Electrohypersensitivity and Multiple Chemical Sensitivity: How They Can Help Diagnosis, Follow-Up, and in Etiopathologic Understanding.
Authors: irigaray philippe , Awaida Natalio , Belpomme Dominique
Published: February 2024

Electrohypersensitivty (EHS) and multiple chemical sensitivity (MCS) are new worldwide emerging neurologic disorders in the framework of sensitivity-related environmental pathology. We have recently extended and confirmed our previous observation showing that EHS and MCS share clinically identical symptoms and may co-exist as a unique, common, sensitivity-related neurologic syndrome in 25% of the cases. There is presently no published biological study of these disorders, except the one we have previously published as preliminary. In the present study, we show that EHS and MCS and the combined syndrome share identical biochemical changes. More precisely, by measuring levels of peripheral blood and urine molecular biomarkers in a cohort of 2,018 consecutive cases, we show that both disorders and the combined syndrome can be objectively characterized, in about 90% of the cases, by a decrease in the production of 6-hydroxymelatonin sulfate in urine, while in 30-50% they are characterized by increased levels of histamine and of heat shock proteins (HSP) 27 and/or 70, and of protein S100B and nitrotyrosine in the peripheral blood. Increased levels of histamine and HSP are indicators of low grade inflammation while increased levels of protein S100B and nitrotyrosine are indicators of blood-brain barrier disruption/opening. In addition, we show that in about 15% of the cases anti-myelin autoantibodies can be detected in the peripheral blood, accounting for the occurrence of an autoimmune response. Sensitivity, specificity and reproducibility of the biochemical tests are discussed, as well as the role of these indicators used as biomarkers for the diagnosis and follow-up of patients. We also discuss cases with undetectable biological change for which they can be nevertheless diagnosed by cerebral neurotransmitters analysis in urine and brain imaging. On the basis of these biological data it is suggested that EHS and/or MCS are new brain disorders, generated via a common etiopathogenic mechanism.
Building health: Understanding how hospital leaders make decisions around interior design and the impact of those decisions on patient well-being
Authors: Lamb Matthew , Kamran Zachary , Shields Landon
Published: February 2024

The design of a hospital’s built environment is no longer treated simply as a place in which health care takes place. Design is a key component of patients’ overall care as well as an influencer of organizational processes. The purpose of this study is to examine how hospital leadership makes decisions about interior design. That is, what do leaders take into consideration when making design decisions? What communicative, systemic, or cultural elements construct the environment wherein design decisions are made? Interviews were conducted with leaders from three different hospitals, from three different countries: United States, United Kingdom, and Saudi Arabia. Our goal in interviewing hospital leadership, from different countries, was to gain a rich and complex understanding about the various aspects that go into decisions leaders make concerning hospital design. Interview data was analyzed, and 5 themes emerged: 1) Organizational processes: Effects on staff, patients, doctors; 2) Structural challenges: Age and retrofitting old/new, budget, resources; 3) Design decisions that impact care: interactions between patients, doctors, staff; 4) Design strategies by function; 5) Strategies for improvement. The results of this study demonstrate the need for hospital leadership to examine their hospital’s design, the importance of culture on design and therapeutic environments, and understand where design will have the greatest impact. Thus, our study addresses the complexities hospital leaders take into consideration to move design from an idea to an actor in the therapeutic environment with real influences on patient care, stress, and medical decision-making.
Smash cut to black: Exploring Maladaptive Psychological Patterns in Tony Soprano and Their Impact on the Audience in The Sopranos
Authors: Mariani Annachiara
Published: February 2024

James Gandolfini's lead role as Tony in The Sopranos has garnered critical attention for its nuanced portrayal of a mafia leader coping with mental health issues. This article explores and analyzes the dysfunctional psychological patterns exhibited by this character throughout the series and the impact on its viewers. This research offers an in-depth exploration into the development and manifestation of Tony Soprano's psychological disorders. It examines the underlying reasons and subsequent repercussions of his behavior combining a psychoanalytic framework and a content analysis methodology. By engaging in these approaches, it provides significant insights on the complex interplay between his delinquent conduct and mental health disorders. It uses qualitative content analysis to closely analyze pivotal episodes and character interactions across all seasons of The Sopranos. Informed by established psychological theories, this study identifies and interprets recurrent behavioral, cognitive, and emotional patterns within Tony Soprano's character. Additionally, it explores the impact of sociocultural factors on his psychological development. This analysis uncovers a range of maladaptive psychological patterns exhibited by Tony Soprano, encompassing antisocial and borderline personality disorders, pervasive anxiety, chronic depression, anger management issues, narcissistic tendencies, and unresolved childhood trauma. These complex dynamics emerge in his relationships with others, impact his decision-making, and significantly add to the richness of his character and the series’ storytelling. The Sopranos presents Tony as an intriguing case study, revealing the complex interplay between criminal behavior and psychological dysfunction. This article underscores the significance of recognizing and addressing psychological struggles in high-stress, morally ambiguous contexts, highlighting the intricacies of human nature. By delving into the layers of Tony Soprano's psyche, one gains valuable insights into this character's enduring relevance and allure and its portrayal in contemporary media. Moreover, this study suggests that Tony's portrayal may serve as a point of identification and reflection for viewers with similar pathological profiles. Understanding his complexity may offer a platform for individuals confronting analogous challenges to cope and seek help. As a result, this study may favorably encourage viewers to empathize with Tony Soprano's psychological difficulties, generating empathy and stimulating conversations regarding mental health depiction in media. Further research in this area has the potential to deepen our comprehension of the relationship between crime, mental health, and personal growth, with implications for both clinical practice and media studies.
COVID-19, Geopolitics, and the Reform of European Pharmaceutical Law: Accelerating Enhanced Medicines Care for Europe?
Authors: Plank Kristine
Published: February 2024

Given the COVID-19 pandemic and intensified geopolitical disruptions, the European Commission, seeking to govern pharmaceutical supply, faced various problems from within and outside the European Union. The authority subsequently submitted far-reaching proposals to revise, amend, and repeal the European Union’s pharmaceutical law. It is against this backdrop that the article examines the different policy impacts on the new pharmaceutical legislation and makes a brief forecast about the extent to which the draft measures, should they come into force as proposed, will contribute to better medicines care in the future. In doing so, the analysis concludes that COVID-19 was a mere accelerator and not the original trigger of most legislative changes. Furthermore, the article argues that, although problems have been identified correctly, some of the approaches to solving them are entrenched in ineffective paths.
Parkinson’s disease and the Interaction of Photobiomodulation, the Microbiome, and Antibiotics: A Case Series A Case Series
Authors: Bicknell Brian , Saltmarche Anita , Hares Orla , Herkes Geoffrey , Liebert Ann
Published: February 2024

It is apparent that there is a close association between the gut microbiome and Parkinson’s disease, with many patients having gut symptoms. Gut microbiome dysfunction may be related to instigation and progression of Parkinson’s disease in many patients. There is also evidence that disrupting the gut microbiome, such as with antibiotics, can increase the risk of developing Parkinson’s disease. Photobiomodulation has the potential to alleviate the symptoms of Parkinson’s disease in both animal models and in humans and has also been shown to alter the microbiome in a mouse model. Here we assessed the interaction between photobiomodulation and the gut microbiome in four people with Parkinson’s disease, three of whom had participated in clinical trials and two of whom were prescribed antibiotics during the photobiomodulation treatment. Patients were treated three times per week using infrared laser treatment to the abdomen and neck with or without LED treatment to the head. Gastrointestinal symptoms were assessed prior to treatment and after 4 weeks and 12 weeks of photobiomodulation therapy and microbiome status was assessed in 3 of the 4 patients. Outcome measures included motor signs and patient-reported non-motor symptoms including symptoms of constipation/diarrhea/gastric motility, and abdominal pain, as well as phylogenetic analysis of microbiome diversity. Participants in this case series were seen as good responders to photobiomodulation treatment, with improvements in motor signs and non-motor symptoms. Gastrointestinal symptoms, including irritable bowel symptoms were improved, and microbiome analysis indicated a generally positive change in bacterial diversity. Antibiotic use during the photobiomodulation treatment had a negative effect on motor and non-motor improvements, as well as disrupting the microbiome. Results of this study suggest that photobiomodulation may have a role in the improvement of the gut microbiome, which could be advantageous in the treatment of Parkinson’s disease, considering the strong microbiome-gut-brain-axis in the disease.
‘I feel like I am more respected here in Thailand’: Indonesian EFL Teachers' Experiences and Challenges in Thai Elementary Schools
Authors: Haryadi Didit
Published: February 2024

With the growth of teacher mobility, where teachers from diverse cultural backgrounds attempt to broaden their teaching experiences, the resulting global community has given rise to new and challenging educational environments. In Thailand, numerous English programs welcome teachers from different countries, accordingly contributing to the nuances of foreign English teachers' experiences. This study aims to delve into the experiences and challenges faced by Indonesian EFL teachers working in Thailand. In the context of the globalized educational system, the inclusion of Indonesian teachers in this study is essential. Their distinct cultural experiences and challenges not only enhance multicultural understanding but also contribute significantly to the existing literature on teaching English in foreign settings. Utilizing a qualitative research approach, this study conducted multiple semi-structured interviews with two Indonesian EFL teachers employed in both a public elementary school and a private elementary school in Thailand. The findings reveal that teaching English in Thailand has provided them with valuable insights and has been a transformative experience, enhanced their professional growth. The findings also provide comprehensive insights into the unique challenges faced by these teachers, particularly regarding language barriers, cultural adaptation, and professional relationships. This study not only illuminates the challenges encountered by teachers but also underscores the considerable potential for personal and professional growth within the ever-evolving landscape of teaching English oversea.
Blink of innocence: A study of paediatric ocular trauma at a tertiary eye care centre in South India
Authors: Sharat Soumya , Sohail J Mohammed
Published: February 2024

To assess the prevalence of ocular trauma and extent of visual loss in paediatric patients at a tertiary care eye hospital in South India.

A retrospective study was conducted on all children of age group 15 years and younger, of both genders, sustaining ocular injuries and seeking care within the ophthalmology outpatient department of a tertiary eye care hospital. The study spanned for a duration of six months. The demographic profile of the participants was recorded, detailed history was taken, followed by standardised ocular evaluation. Orbital imaging was done where deemed necessary. An eye was considered blind due to trauma if best corrected visual acuity for distance was worse than 3/60 due to trauma. Patients with pre-existing low vision in the affected eye were excluded in the study.

50 children were included in the study. The mean age upon initial presentation manifested was 9.8 years. The demographic distribution revealed a predilection for children within the age group of 11 to 15 years, constituting 38% of the sampled populace, with the subsequent demographic tier of 5-10 years encompassing 36%. Noteworthy differentials emerged between rural and urban cohorts, with rural representation at 64% and urban at 36%. The predominant ocular injuries were categorized as 72% closed globe injuries and 18% open globe injuries. Operative interventions were administered to 54% of the cases, while the remaining 46% were subject to conservative therapeutic modalities. Within the subset of closed globe injuries necessitating surgical intervention (36%), specific pathologies included lid tear, canalicular tear, and traumatic cataract.

Ocular trauma in paediatric population can lead to permanent blindness and visual handicap. It also affects the social, emotional and psychological development of the child. Most of these injuries can be prevented by supervision of children during play, educating the children, family members and teachers regarding ocular health and hygiene.
OSSN: An underrated neoplasia of the eye
Authors: Khanna Vanshika , Jaiswal Ram Kumar , Wahi Dipti
Published: February 2024

: Ocular surface squamous cell carcinoma (OSSN) is a general term for various conjunctival tumors, including conjunctival intraepithelial neoplasia (CIN) and squamous cell carcinoma (SCC).

: To evaluate the clinico-demographic characteristics and histopathological findings of ocular surface squamous cell carcinoma.

: eyes of 47 patients aged 21 to 80 years with conjunctival tumors were included in the study and underwent excisional biopsy and subsequent histopathological examination.

: Statistically significant associations were found with age, symptom duration, and lesion size (p<0.05).

Benign and preinvasive lesions are more common than invasive lesions.
Pharmacological activities of essential oils from some flowers, plants and aromatic seeds – A review
Authors: Murali Krishna Kumar M. , Nandikatti Vijayalakshmi , Nagasree K. Poorna
Published: February 2024

Volatile oils or essential oils are the secondary plant metabolites producing from different plant parts like flowers, leaves, fruits, seeds, stem, roots and their barks. These are chemically classified as terpenoids, which are hydrocarbons with a hydroxyl or carbonyl group. These are having different organic exercises and utilized as cure in Gastrointestinal issues, cold, hack, skin illnesses and so forth. These oils revealed for their pharmacological impacts like enemy of oxidant, hostile to bacterial, mitigating exercises and as Carminative. Ayurveda's founding country is India. There are numerous plants in India that can produce essential oils, which are frequently used in our daily lives. In this review, we want to talk about the biological activities of essential oils that come from flowers (like rose, jasmine, chrysanthemum, marigold), plant leaves (like marjoram, coriander, and mentha), and aromatic seeds (like fennel, caraway, cumin, and coriander), all of which are consumed on a daily basis and contribute to the cleanliness of our environment and health.
Fabric phase sorptive extraction: A sustainable approach in analysis of pharmaceutical product
Authors: Prajapati Parixit , Patel Nutan , Kankva Divyesh
Published: February 2024

As the pharmaceutical industry continues to evolve, there is an increasing demand for sustainable and efficient analytical techniques in the analysis of pharmaceutical products. This manuscript explores the application of Fabric Phase Sorptive Extraction (FPSE) as a novel and sustainable approach for the extraction and analysis of pharmaceutical compounds. FPSE, a recent advancement in sample preparation, offers a greener alternative by utilizing a fabric-like sorbent material. The environmentally friendly nature of FPSE, with reduced solvent consumption and waste generation, aligns with the principles of green analytical chemistry. Case studies involving the analysis of various pharmaceutical products showcase the versatility and applicability of FPSE in different matrices.
Novel positioning of L. (Black seed) from farm to pharma indexed in pharmacopeia
Authors: I.M. Almoselhy Rania , Usmani Afreen
Published: February 2024

The current study examines the regulatory status and inclusion of in pharmacopeias across diverse regions. The regulatory landscape varies globally, with some countries recognizing it as a traditional medicine in pharmacopeias, while others impose restrictions due to safety and efficacy concerns. The lack of standardized guidelines complicates its status, ranging from dietary supplement to traditional herbal medicine in different regions. A pivotal shift is observed in the Egyptian Herbal Monograph Volume 3, marking Black Seed's evolution from traditional medicinal use to a recognized pharmaceutical preparation in the pharmacopeia. This transition signifies a move towards evidence-based medicine, emphasizing rigorous scientific scrutiny and standardization. The integration of Black Seed underscores growing recognition of its efficacy and safety, transforming it into a pharmaceutical product and consolidating its position in mainstream healthcare. The inclusion not only enhances patient accessibility but also instills confidence among healthcare practitioners, solidifying Black Seed as a trusted therapeutic agent. The debate around N. sativa's inclusion continues, with traditional medicine systems endorsing its value, while modern pharmacopeias grapple with standardization and quality control. N. sativa emerges as a promising natural resource, necessitating comprehensive documentation for its prospective inclusion in evidence-based healthcare practices and official guidelines.
Audacious Dancing
Authors: Johansson Michelle
Published: February 2024

Audacious Dancing is an evolving framework for critically considering indigenous Pasifika art-making, legacy-leaving, education, service and leadership through the lens of social justice. Located at the juncture of the performing arts and education for young Pasifika leaders in South Auckland, Aotearoa New Zealand, and drawing on indigenous scholarship in the performing arts, Audacious Dancing offers a way to consider what it means to be a ‘creative native’, learning and leading across generations, cultures and artforms. The four strands - courageous space, indigenous excellence, critical hope and powerful action - weave intergenerational indigenous knowledges with what it means to be growing up Pasifika in the largest Polynesian city in the world.
Relic
Authors: Hafoka Tali Alisa
Published: February 2024

Once, every part of the coconut tree had multiple practical uses that supported daily life (upper panel). Today, many of the coconut tree’s uses have been replaced by other materials. For some, the role of the coconut tree has been reduced to merely decorative (lower panel - topiary pot), creating an atmosphere of paradise and garnishing your slice of coconut cake.

Oil on Canvas

Dimensions:

72” x 24” (Two 36” x 24”) [inches]

6’ x 2’ (Two 3’ x 2’) [feet]

182.88 cm x 60.96 cm (Two 91.44 cm x 60.96 cm) [centimeters]
Our Search for Intergenerational Rhythms as Tongan Global Scholars
Authors: Faleolo Ruth (Lute) , Fehoko Edmond , Dyck Dagmar , Hafu-Fetokai Cathleen , Malungahu Gemma , Clark Zaramasina L , Hafoka ‘Esiteli , Tovo Finausina , Taufui Mikato Fa‘avae David
Published: February 2024

Our search for collective meaning-making across spaces and places as Tongan global scholars carries intergenerational rhythms. This article is a diasporic collaboration between members of the Tongan Global Scholars Network (TGSN), an online cultural collective drawn together through creatively critical rhythms and a desire to make space for ongoing criticalities through Tongan concepts, knowledge, and approaches. Employing the art of e-talanoa in our search for ways of crafting meaning, we unfold our narratives about TGSN’s humble beginnings using a range of modalities expressed as words, images, screenshots, and poetry. Our desire to connect early career scholars of Tongan heritage across the diaspora of Australia, the United States of America, Aotearoa New Zealand, and Tonga via the online space, led to enabling intergenerational relational rhythms between more seasoned and emerging scholars, sharing their understanding of Tongan knowledge and its relevance in the dominant Western academe. Intergenerational rhythms are central to TGSN’s survival. As a global network, TGSN continues to provide meaningful spaces for creatively critical meaning- making and intergenerational collaborative dialogue.