bluuebunny/crossref_metadata_2025 huggingface dataset:
Mechanical Properties of High-Performance Steel-Fibre-Reinforced Concrete and Its Application in Underground Mine Engineering
Authors: Li Xiang , Xue Weipei , Fu Cao , Yao Zhishu , Liu Xiaohu
Published: August 2019

In order to economically and reasonably solve the problem of mineshaft support in complex geological conditions, the mechanical properties of high-performance steel-fiber-reinforced concrete (HPSFRC) and its application in mineshaft lining structures were investigated in this study. Firstly, the mix proportion of HPSFRC for the mineshaft lining structure was obtained through raw material selection and preparation testing. Then, a series of mechanical property tests were conducted. The test results showed that the compressive, flexural, and tensile strengths of HPSFRC were 9%, 71%, and 53% higher than that of ordinary concrete, respectively. The fracture toughness of HPSFRC was 75% higher than that of the ordinary concrete and the fracture energy of HPSFRC was 16 times that of the ordinary concrete. Finally, the model test results of the HPSFRC shaft lining structure showed that the crack resistance, toughness, and bearing capacity of the shaft lining structure had been significantly improved under a non-uniform confining load because of the replacement of ordinary concrete with HPSFRC. HPSFRC was proved to be an ideal material for mineshaft support structures under complex geological conditions.
Impact of Electrocautery on Fatigue Life of Spinal Fusion Constructs—An In Vitro Biomechanical Study
Authors: Almansour Haidara , Sonntag Robert , Pepke Wojciech , Bruckner Thomas , Kretzer Jan Philippe , Akbar Michael
Published: August 2019

Instrumentation failure in the context of spine surgery is attributed to cyclic loading leading to formation of fatigue cracks, which later propagate and result in rod fracture. A biomechanical analysis of the potential impact of electrocautery on the fatigue life of spinal implants has not been previously performed. The aim of this study was to assess the fatigue life of titanium (Ti) and cobalt-chrome (CoCr) rod-screw constructs after being treated with electrocautery. Twelve spinal constructs with CoCr and Ti rods were examined. Specimens were divided into four groups by rod material (Ti and CoCr) and application of monopolar electrocautery on the rods’ surface (control-group and electrocautery-group). Electrocautery was applied on each rod at three locations, then constructs were cyclically tested. Outcome measures were load-to-failure, total number of cycles-to-failure, and location of rod failure. Ti-rods treated with electrocautery demonstrated a significantly decreased fatigue life compared to non-treated Ti-rods. Intergroup comparison of cycles-to-failure revealed a significant mean decrease of almost 9 × 105 cycles (p = 0.03). No CoCr-rods failed in this experiment. Electrocautery application on the surface of Ti-rods significantly reduces their fatigue life. Surgeons should exercise caution when using electrocautery in the vicinity of Ti-rods to mitigate the risk of rod failure.
Electrochemistry and Rapid Electrochromism Control of MoO3/V2O5 Hybrid Nanobilayers
Authors: Chang Chung-Chieh , Chi Po-Wei , Chandan Prem , Lin Chung-Kwei
Published: August 2019

MoO3/V2O5 hybrid nanobilayers are successfully prepared by the sol–gel method with a spin- coating technique followed by heat -treatment at 350 °C in order to achieve a good crystallinity. The composition, morphology, and microstructure of the nanobilayers are characterized by a scanning electron microscope (SEM) and X-ray diffractometer (XRD) that revealed the a grain size of around 20–30 nm, and belonging to the monoclinic phase. The samples show good reversibility in the cyclic voltammetry studies and exhibit an excellent response to the visible transmittance. The electrochromic (EC) window displayed an optical transmittance changes (ΔT) of 22.65% and 31.4% at 550 and 700 nm, respectively, with the rapid response time of about 8.2 s for coloration and 6.3 s for bleaching. The advantages, such as large optical transmittance changes, rapid electrochromism control speed, and excellent cycle durability, demonstrated in the electrochromic cell proves the potential application of MoO3/V2O5 hybrid nanobilayers in electrochromic devices.
Effects of Transverse Crack on Chloride Ions Diffusion and Steel Bars Corrosion Behavior in Concrete under Electric Acceleration
Authors: Du Fengyin , Jin Zuquan , Xiong Chuansheng , Yu Yong , Fan Junfeng
Published: August 2019

Cracks greatly impact the durability of concrete structures due to their influence on the migration of chloride ions and the corrosion process of steel bars. This study investigates the effects of transverse cracks on chloride diffusion and the corrosion behavior of two types of steel bars (low carbon steel and corrosion resistant steel) in fly ash concrete with 1 kg/m3 solution-polymerized super absorbent polymer. Electrochemical impedance spectroscopy was used to monitor the chloride-induced corrosion behavior of steel bars in concrete. The chloride profile around cracks was tested via chemical titration. The corrosion products diffusion area was photographed and measured to evaluate the influences of cracks on the corrosion degree of steel bars. Transverse cracks greatly influence the chloride ion transport. When their width is less than 0.15 mm, cracks exert little influence on both chloride diffusion and steel corrosion. When the crack width exceeds 0.15 mm, the chloride ion transmission coefficient is significantly improved and steel corrosion is accelerated. However, when the crack width exceeds 0.20 mm, this effect is gradually weakened. Based on the experimental data, a quantitative relationship between the crack width and the chloride ion transmission coefficient in electric acceleration was established.
Biocompatibility and Mineralization Activity of Three Calcium Silicate-Based Root Canal Sealers Compared to Conventional Resin-Based Sealer in Human Dental Pulp Stem Cells
Authors: Seo Deog-Gyu , Lee Donghee , Kim Yong-Min , Song Dani , Kim Sin-Young
Published: August 2019

The purpose of this study was to compare the cytotoxic effects and mineralization activity of three calcium silicate-based root canal sealers to those of a conventional resin-based sealer. Experiments were performed using human dental pulp stem cells grown in a monolayer culture. The root canal sealers tested in this study were EndoSequence BC Sealer (Brasseler), BioRoot RCS (Septodont), Endoseal MTA (Maruchi), and AH Plus (Dentsply DeTrey). Experimental disks 6 mm in diameter and 3 mm in height were made and stored in a 100% humidity chamber at 37 °C for 72 h to achieve setting. The cytotoxicity of various root canal sealers was evaluated using a methyl-thiazoldiphenyl-tetrazolium (MTT) assay. To evaluate cell migration ability, a scratch wound healing method was used, and images of the scratch area were taken using a phase-contrast microscope. Cell morphology was evaluated by a scanning electron microscope after direct exposure for 72 h to each sealer disk. In the cell viability assay, there were no significant differences between the EndoSequence BC, BioRoot RCS, Endoseal MTA, and control groups in any experimental period (p > 0.05). In the cell migration assay, there were no significant differences between the EndoSequence BC, Endoseal MTA, and control groups in any experimental period (p > 0.05). BioRoot RCS exhibited slower cell migration relative to EndoSequence BC and Endoseal MTA for up to 72 h (p < 0.05). Conversely, it showed a similar wound healing percentage at 96 h (p > 0.05). In an evaluation of cell morphology, cells in direct contact with EndoSequence BC, BioRoot RCS, and Endoseal MTA disks showed superior spreading compared to those in contact with the AH Plus disk. In an Alizarin red staining assay, EndoSequence BC, BioRoot RCS, and Endoseal MTA showed a significant increase in mineralized nodule formation compared to the AH Plus group (p < 0.05). In conclusion, all calcium silicate-based root canal sealers tested in this study showed good biological properties and mineralization activity compared to conventional resin-based sealer.
A New Reversible Phase Transformation of Intermetallic Ti3Sn
Authors: Du Minshu , Cui Lishan , Liu Feng
Published: August 2019

Ti3Sn has received increasing attention as a high damping metallic material and as an anode material for rechargeable lithium-ion batteries. However, a heated dispute concerning the existence of solid state phase transformation of stoichiometric Ti3Sn impedes its development. Here, thermal-induced reversible phase transformation of Ti3Sn is demonstrated to happen at around 300 K by the means of in-situ variable-temperature X-ray diffraction (XRD) of Ti3Sn powder, which is also visible for bulk Ti3Sn on the thermal expansion curve by a turning at 330 K. The new phase’s crystal structure of Ti3Sn is determined to be orthorhombic with a space group of Cmcm and the lattice parameters of a = 5.87 Å, b = 10.37 Å, c = 4.76 Å respectively, according to selected area electron diffraction patterns in transmission electron microscope (TEM) and XRD profiles. The hexagonal → orthorhombic phase transformation is calculated to be reasonable and consistent with thermodynamics theory. This work contributes to a growing knowledge of intermetallic Ti3Sn, which may provide fundamental insights into its damping mechanism.
Biosorption of Methylene Blue Dye Using Natural Biosorbents Made from Weeds
Authors: Silva Francisco , Nascimento Lorena , Brito Matheus , da Silva Kleber , Paschoal Waldomiro , Fujiyama Roberto
Published: August 2019

The purpose of this work is to make use of vegetables that, although widely found in nature, there are few applications. The weeds used here, Cyanthilium cinereum (L.) H. Rob (CCLHR) and Paspalum maritimum (PMT) found in the Amazon region of Belém state of Pará-Brazil, contribute to the problem of water contamination by the removal of the methylene blue dye through the biosorption process, taking advantage of other materials for economic viability and processing. The influences of parameters such as, biosorbent dose, contact time, and initial concentration of dye were examined. The characterizations were realized using SEM to verify the morphology of the material and spectroscopy in the FTIR region. As for the adsorption mechanism, the physical adsorption mechanism prevailed. The time required for the system to reach equilibrium for both biosorbents was from 50 min, following a kinetics described by the pseudo-second order model. The adsorption isotherm data for PMT were better adjusted to the Langmuir model and the biosorption capacity ( q m a x ) value was (56.1798 mg/g). CCLHR was better adjusted to the Freundlich model and its maximum biosorption capacity was 76.3359 mg/g. Thus, these weed species are promising for the biosorption of methylene blue dye in effluents.
Possibilities of Fucoidan Utilization in the Development of Pharmaceutical Dosage Forms
Authors: Citkowska Aleksandra , Szekalska Marta , Winnicka Katarzyna
Published: August 2019

Fucoidan is a polysaccharide built from L-fucose molecules. The main source of this polysaccharide is the extracellular matrix of brown seaweed (Phaeophyta), but it can be also isolated from invertebrates such as sea urchins (Echinoidea) and sea cucumbers (Holothuroidea). Interest in fucoidan is related to its broad biological activity, including possible antioxidant, anti-inflammatory, antifungal, antiviral or antithrombotic effects. The potential application of fucoidan in the pharmaceutical technology is also due to its ionic nature. The negative charge of the molecule results from the presence of sulfate residues in the C-2 and C-4 positions, occasionally in C-3, allowing the formation of complexes with other oppositely charged molecules. Fucoidan is non-toxic, biodegradable and biocompatible compound approved by Food and Drug Administration (FDA) as Generally Recognized As Safe (GRAS) category as food ingredient. Fucoidan plays an important role in the pharmaceutical technology, so in this work aspects concerning its pharmaceutical characteristics and designing of various dosage forms (nanoparticles, liposomes, microparticles, and semisolid formulations) with fucoidan itself and with its combinations with other polymers or components that give a positive charge were reviewed. Advantages and limitations of fucoidan utilization in the pharmaceutical technology were also discussed.
High Brightness Organic Light-Emitting Diodes with Capillary-Welded Hybrid Diameter Silver Nanowire/Graphene Layers as Electrodes
Authors: Zhang Jianhua , Li Yiru , Wang Bo , Hu Huaying , Wei Bin , Yang Lianqiao
Published: August 2019

The development of silver nanowire electrodes is always limited due to some disadvantages, such as roughness, oxidative properties, and other disadvantages. In this research, a capillary-welded silver nanowire/graphene composite film was used as an electrode for organic light-emitting diode (OLED) devices. As an encapsulation layer, graphene reduced the surface roughness and the oxidation probability of silver nanowires. The composite electrode showed an excellent transmittance of 91.5% with low sheet resistant of 26.4 ohm/sq. The devices with the silver nanowire/graphene composite electrode emitted green electroluminescence at 516 nm, and the turn-on voltage was about 3.8 V. The maximum brightness was 50810 cd/cm2, which is higher than the indium tin oxide-based (ITO-based) devices with the same configuration. Finally, it was proved that the silver nanowire/graphene composite electrodes possessed better heat dissipation than the ITO-based ones under energization. In summary, it means that this novel silver nanowires/graphene electrode has great potential in OLED device applications.
Flexible Multi-Layer Semi-Dry Electrode for Scalp EEG Measurements at Hairy Sites
Authors: Hua Haoqiang , Tang Wei , Xu Xiangmin , Feng David Dagan , Shu Lin
Published: August 2019

One of the major challenges of daily wearable electroencephalogram (EEG) monitoring is that there are rarely suitable EEG electrodes for hairy sites. Wet electrodes require conductive gels, which will dry over the acquisition time, making them unstable for long-term EEG monitoring. Additionally, the electrode–scalp impedances of most dry electrodes are not adequate for high quality EEG collection at hairy sites. In view of the above problems, a flexible multi-layer semi-dry electrode was proposed for EEG monitoring in this study. The semi-dry electrode contains a flexible electrode body layer, foam layer and reservoir layer. The probe structure of the electrode body layer enables the electrode to work effectively at hairy sites. During long-term EEG monitoring, electrolytes stored in the reservoir layer are continuously released through the foam layer to the electrode–scalp interface, ensuring a lower electrode–scalp contact impedance. The experimental results showed that the average electrode–scalp impedance of the semi-dry electrode at a hairy site was only 23.89 ± 7.44 KΩ at 10 Hz, and it was lower than 40 KΩ over a long-term use of 5 h. The electrode performed well in both static and dynamic EEG monitoring, where the temporal correlation with wet electrode signals at the hairy site could reach 94.25% and 90.65%, respectively, and specific evoked EEG signals could be collected. The flexible multi-layer semi-dry electrode can be well applied to scalp EEG monitoring at hairy sites, providing a promising solution for daily long-term monitoring of wearable EEGs.
Editorial for the Special Issue on Self-Assembly of Polymers
Authors: Vikulina Anna S. , Volodkin Dmitry
Published: August 2019

The self-assembly of polymers is a powerful tool for producing various functional materials with a high precision from nano- to macroscale [...]
Editorial for the Special Issue on Microfluidics for Cells and Other Organisms
Authors: van Noort Danny
Published: August 2019

It is my great pleasure to present to you this first volume of 13 papers on the subject of Microfluidics for Cells and other Organisms [...]
Zircon U-Pb, Molybdenite Re-Os and Quartz Vein Rb-Sr Geochronology of the Luobuzhen Au-Ag and Hongshan Cu Deposits, Tibet, China: Implications for the Oligocene-Miocene Porphyry–Epithermal Metallogenic System
Authors: Huang Hanxiao , Liu Hong , Li Guangming , Zhang Linkui , Cao Huawen , Zhou Qing , Wang Xinxin , Yan Guoqiang
Published: August 2019

The Gangdese metallogenic belt in Tibet is an important copper and iron polymetallic, metallogenic belt in western China. The Luobuzhen epithermal Au-Ag and Hongshan porphyry Cu deposits, as two new discovery deposits in the last few years, are located in the western Gangdese metallogenic belt. In this paper, we present quartz vein Rb-Sr isochron, zircon U-Pb and molybdenite Re-Os ages for a better understanding of the minerallogenetic epoch of the deposits. Geochronological data show that the Rb-Sr isochron age of a quartz vein in a Luobuzhen Au-Ag deposit is 21.1 ± 1.8 Ma (MSWD (mean standard weighted deviation) = 0.19), zircon U-Pb ages from diorite and granodiorite porphyry in Hongshan Cu deposit are 50.0 ± 0.4 Ma (MSWD = 0.94) and 23.7 ± 0.1 Ma (MSWD = 0.73), respectively, and a Re-Os isochron age of molybdenite in Hongshan Cu deposit is 23.0 ± 2.0 Ma (MSWD = 0.014). These data suggest that the Luobuzhen epithermal Au-Ag and Hongshan porphyry Cu deposits formed at ca. 23–21 Ma, which were controlled by the same magmatic hydrothermal events. Formation of both the Luobuzhen and Hongshan deposits were obviously earlier than the Miocene porphyry metallogenetic events in the Gangdese porphyry copper belt.
Novel Carbon Nanoparticles Derived from Biodiesel Soot as Lubricant Additives
Authors: Li Chuan , Li Mingling , Wang Xinyun , Feng Weimin , Zhang Qiangqiang , Wu Bo , Hu Xianguo
Published: August 2019

The objective of this study was to investigate the roles and tribological mechanisms of onion-like carbon nanoparticles derived from biodiesel soot (BDS) when applied in water (H2O) and liquid paraffin (LP). In this study, we prepared nitric acid-treated BDS (NA-BDS) as an additive to H2O and NA-BDS modified with oleylamine (NA-BDS-OLA) as an additive to LP. Raman spectroscopy, field-emission transmission electron microscopy, Fourier transform infrared spectroscopy, and zeta potentiometry were used to characterize the results of the nitric acid treatment and oleylamine modification. The tribological behaviors and corresponding mechanisms of the new onion-like carbon nanoparticles were evaluated using a ball-on-disc reciprocating tribometer, as well as field-emission scanning electron microscopy, three-dimensional laser scanning microscopy, and Raman spectroscopy. The results indicated that the additives NA-BDS and NA-BDS-OLA, which were onion-like carbon nanoparticles with sizes ranging from 35 to 40 nm, enhanced the antiwear and friction reduction properties of H2O and LP, respectively. Through tribo-mechanisms, these types of soot can serve as spacers and ball bearings between the rubbing surfaces. Moreover, exfoliation under a high load as a result of the formation of a graphitic layer facilitates easy shearing.
Ferroelectric Polarization-Enhanced Photocatalysis in BaTiO3-TiO2 Core-Shell Heterostructures
Authors: Liu Xiaoyan , Lv Siyi , Fan Baoyan , Xing An , Jia Bi
Published: August 2019

Suppressing charge recombination and improving carrier transport are key challenges for the enhancement of photocatalytic activity of heterostructured photocatalysts. Here, we report a ferroelectric polarization-enhanced photocatalysis on the basis of BaTiO3-TiO2 core-shell heterostructures synthesized via a hydrothermal process. With an optimal weight ratio of BaTiO3 to TiO2, the heterostructures exhibited the maximum photocatalytic performance of 1.8 times higher than pure TiO2 nanoparticles. The enhanced photocatalytic activity is attributed to the promotion of charge separation and transport based on the internal electric field originating from the spontaneous polarization of ferroelectric BaTiO3. High stability of polarization-enhanced photocatalysis is also confirmed from the BaTiO3-TiO2 core-shell heterostructures. This study provides evidence that ferroelectric polarization holds great promise for improving the performance of heterostructured photocatalysts.
Preparation and Characterization of Nanocomposite Films Containing Nano-Aluminum Nitride and Cellulose Nanofibrils
Authors: Nie Shuangxi , Zhang Yuehua , Wang Linmao , Wu Qin , Wang Shuangfei
Published: August 2019

Nanocomposites consisting of cellulose nanofibrils (CNFs) and nano-aluminum nitride (AlN) were prepared using a simple vacuum-assisted filtration process. Bleached sugarcane bagasse pulp was treated with potassium hydroxide and sodium chlorite, and was subsequently ultra-finely ground and homogenized to obtain CNFs. Film nanocomposites were prepared by mixing CNFs with various AlN amounts (0–20 wt.%). X-ray diffraction revealed that the crystal form of CNF-AlN nanocomposites was different to those of pure CNFs and AlN. The mechanical performance and thermal stability of the CNF-AlN nanocomposites were evaluated through mechanical tests and thermogravimetric analysis, respectively. The results showed that the CNF-AlN nanocomposites exhibited excellent mechanical and thermal stability, and represented a green renewable substrate material. This type of nanocomposite could present great potential for replacing traditional polymer substrates, and could provide creative opportunities for designing and fabricating high-performance portable electronics in the near future.
Thin Functional Polymer Films by Electropolymerization
Authors: Palma-Cando Alex , Rendón-Enríquez Ibeth , Tausch Michael , Scherf Ullrich
Published: August 2019

Intrinsically conducting polymers (ICPs) have been widely utilized in organic electronics, actuators, electrochromic devices, and sensors. Many potential applications demand the formation of thin polymer films, which can be generated by electrochemical polymerization. Electrochemical methods are quite powerful and versatile and can be utilized for investigation of ICPs, both for educational purposes and materials chemistry research. In this study, we show that potentiodynamic and potentiostatic techniques can be utilized for generating and characterizing thin polymer films under the context of educational chemistry research and state-of-the-art polymer research. First, two well-known bifunctional monomers (with only two linking sites)—aniline and bithiophene—and their respective ICPs—polyaniline (PANI) and polybithiophene (PBTh)—were electrochemically generated and characterized. Tests with simple electrochromic devices based on PANI and PBTh were carried out at different doping levels, where changes in the UV-VIS absorption spectra and color were ascribed to changes in the polymer structures. These experiments may attract students’ interest in the electrochemical polymerization of ICPs as doping/dedoping processes can be easily understood from observable color changes to the naked eye, as shown for the two polymers. Second, two new carbazole-based multifunctional monomers (with three or more linking sites)—tris(4-(carbazol-9-yl)phenyl)silanol (TPTCzSiOH) and tris(3,5-di(carbazol-9-yl)phenyl)silanol (TPHxCzSiOH)—were synthesized to produce thin films of cross-linked polymer networks by electropolymerization. These thin polymer films were characterized by electrochemical quartz crystal microbalance (EQCM) experiments and nitrogen sorption, and the results showed a microporous nature with high specific surface areas up to 930 m2g−1. PTPHxCzSiOH-modified glassy carbon electrodes showed an enhanced electrochemical response to nitrobenzene as prototypical nitroaromatic compound compared to unmodified glassy carbon electrodes.
Comparing Different Residential Neighborhood Definitions and the Association Between Density of Restaurants and Home Cooking Among Dutch Adults
Authors: Pinho Maria Gabriela M. , Mackenbach Joreintje D. , Charreire Hélène , Oppert Jean-Michel , Rutter Harry , Beulens Joline W. J. , Brug Johannes , Lakerveld Jeroen
Published: August 2019

The definition of neighborhoods as areas of exposure to the food environment is a challenge in food environment research. We aimed to test the association of density of restaurants with home cooking using four different definitions of residential neighborhoods. We also tested effect modification by age, length of residency, education, and income. This innovative cross-sectional study was conducted in the Netherlands (N = 1245 adults). We calculated geographic information system-based measures of restaurant density using residential administrative neighborhood boundaries, 800 m and 1600 m buffers around the home and respondents’ self-defined boundaries (drawn by the respondents on a map of their residential area). We used adjusted Poisson regression to test associations of restaurant density (tertiles) and the outcome ”weekly consumption of home-cooked meals” (six to seven as compared to five days per week (day/week) or fewer). Most respondents reported eating home-cooked meals for at least 6 day/week (74.2%). Regardless of the neighborhood definition used, no association between food environment and home cooking was observed. No effect modification was found. Although exposure in terms of density of restaurants was different according to the four different neighborhood definitions, we found no evidence that the area under study influences the association between density of restaurants and home cooking among Dutch adults.
Impact of Beef and Beef Product Intake on Cognition in Children and Young Adults: A Systematic Review
Authors: An Ruopeng , Nickols-Richardson Sharon M , Khan Naiman , Liu Jianxiu , Liu Ruidong , Clarke Caitlin
Published: August 2019

(1) Background: Undernutrition and micronutrient deficiency have been consistently linked to cognitive impairment among children and young adults. As a primary source of dietary animal protein, beef consumption holds the potential to improve diet quality and positively influence cognitive function. This study systematically reviewed evidence linking beef intake to cognition among children and young adults. (2) Methods: A literature search was conducted in seven electronic bibliographic databases for studies assessing the impact of beef consumption on cognition. (3) Results: We identified eight studies reporting results from five unique interventions. Two interventions were conducted in Kenya, two in the U.S. and one in four countries including Guatemala, Pakistan, Democratic Republic of the Congo and Zambia. Only one intervention employed a non-feeding control arm and found beef consumption to improve cognitive abilities compared to the control. However, the other interventions comparing beef consumption to other food types found no consistent result. (4) Conclusions: Evidence pertaining to the impact of beef consumption on cognition remains limited due to the small and heterogeneous set of studies. Future research should adopt a population representative sample and longer follow-up period, employ a non-feeding control arm and comprehensively measure nutrient intakes among study participants.
Dietary Diversity and Child Development in the Far West of Nepal: A Cohort Study
Authors: Thorne-Lyman Andrew , Shrestha Merina , Fawzi Wafaie , Pasqualino Monica , Strand Tor , Kvestad Ingrid , Hysing Mari , Joshi Neena , Lohani Mahendra , Miller Laurie
Published: August 2019

Poverty adversely affects child development through multiple pathways in low- and middle-income countries. Relationships between diet and child development are poorly understood. In this study, we aimed to explore these associations in a longitudinal cohort of 305 children in rural Nepal (baseline mean age 14 months), evaluating dietary diversity and the consumption of specific food groups at three timepoints over 1.5 years. Child development was assessed using the Ages and Stages questionnaire-version 3 (ASQ-3). Associations between the number of days that children consumed minimum dietary diversity (MDD) (≥4/8 items) and specific food groups over time (range 0–3) and total and subscale ASQ scores at age 23–38 months were estimated using multiple linear and logistic regression, dichotomizing scores at the lowest quartile. After adjusting for confounders, each additional day of consuming MDD was associated with a 35% reduction in the odds of low total ASQ score [OR 0.65, 95% CI (0.46, 0.92)]. The consumption of animal source foods [OR 0.64, (0.46, 0.89)], and vegetables/fruits [OR 0.60, (0.41, 0.90), but not processed foods [OR 0.99, (0.62, 1.59)] was associated with lower odds of low total development. Vegetables, fruits and animal source foods may be important for child development in this setting.
Higher Pro-Inflammatory Dietary Score is Associated with Higher Hyperuricemia Risk: Results from the Case-Controlled Korean Genome and Epidemiology Study_Cardiovascular Disease Association Study
Authors: Kim Hye Sun , Kwon Minji , Lee Hyun Yi , Shivappa Nitin , R. Hébert James , Sohn Cheongmin , Na Woori , Kim Mi Kyung
Published: August 2019

In previous studies, the elevated dietary inflammatory index (DII®) scores have been consistently associated with several chronic diseases. However, the relationship with hyperuricemia remains unknown. The aim of this study was to determine if the DII is associated with hyperuricemia risk. The study included 13,701 participants (men 5102; women 8599) in a large-scale cross-sectional study in South Korea. A validated semi-quantitative food frequency questionnaire (SQFFQ) was used to measure dietary intake, and blood samples were obtained to determine hyperuricemia. As the DII score increased, the hyperuricemia risk increased among women (OR 1.35, 95% CI 1.03–1.77, p trend = 0.02). However, no significant results were found for men. Women with lower BMI scores had higher risks of hyperuricemia with higher DII scores (OR 1.62, 95% CI 1.05–2.52, p trend = 0.03). As the DII increased, however, only women who consumed alcohol (“past or current drinkers”) had higher risks of hyperuricemia (OR 1.92, 1.22–3.02, p trend = 0.004). Among the DII components, intake of flavonoids showed a significant association with the hyperuricemia risk in women (OR 0.75, 0.59–0.96, p trend = 0.03). Our results suggest that higher intake of pro-inflammatory diet is significantly associated with higher risk of hyperuricemia among women. These results reinforce the importance of less pro-inflammatory habitual dietary patterns in lowering the risk of hyperuricemia and secondary afflictions such as cardiovascular diseases.
Impact of Foods and Dietary Supplements Containing Hydroxycinnamic Acids on Cardiometabolic Biomarkers: A Systematic Review to Explore Inter-Individual Variability
Authors: Martini Daniela , Chiavaroli Laura , González-Sarrías Antonio , Bresciani Letizia , Palma-Duran Susana A. , Dall’Asta Margherita , Deligiannidou Georgia-Eirini , Massaro Marika , Scoditti Egeria , Combet Emilie , Maksimova Viktorija , Urpi-Sarda Mireia , Kontogiorgis Christos A. , Andrés-Lacueva Cristina , Gibney Eileen R. , Del Rio Daniele , Morand Christine , Garcia-Aloy Mar , Rodriguez-Mateos Ana , Mena Pedro
Published: August 2019

Plant-based diets rich in bioactive compounds such as polyphenols have been shown to positively modulate the risk of cardiometabolic (CM) diseases. The inter-individual variability in the response to these bioactives may affect the findings. This systematic review aimed to summarize findings from existing randomized clinical trials (RCTs) evaluating the effect of hydroxycinnamic acids (HCAs) on markers of CM health in humans. Literature searches were performed in PubMed and the Web of Science. RCTs on acute and chronic supplementation of HCA-rich foods/extracts on CM biomarkers were included. Forty-four RCTs (21 acute and 23 chronic) met inclusion criteria. Comparisons were made between RCTs, including assessments based on population health status. Of the 44 RCTs, only seven performed analyses on a factor exploring inter-individual response to HCA consumption. Results demonstrated that health status is a potentially important effect modifier as RCTs with higher baseline cholesterol, blood pressure and glycaemia demonstrated greater overall effectiveness, which was also found in studies where specific subgroup analyses were performed. Thus, the effect of HCAs on CM risk factors may be greater in individuals at higher CM risk, although future studies in these populations are needed, including those on other potential determinants of inter-individual variability. PROSPERO, registration number CRD42016050790.
A Review of Guidelines/Guidance from Various Countries Around the World for the Prevention and Management of Travellers’ Diarrhoea: A Pharmacist’s Perspective
Authors: Hitch Geeta
Published: August 2019

International travel is growing and pharmacists are well placed to provide travel health services for the prevention and management of travellers’ diarrhoea (TD). Legislation changes in many countries has enabled pharmacists to access prescription only medicines and vaccinations to provide advice and over the counter medicines for the prevention and management for travel health services; this makes sense since pharmacies are easily accessible to the public and are the patient’s first port of call in the event of any illness. Currently, whilst many guidelines/guidance exist worldwide for the prevention and management of TD, there is no review that focuses on similarities and differences between these and between guidelines on TD and travel related and non-travel related acute diarrhoea. There is also a lack of publication on legislation and the need for evidence based training for all prescribers to provide travel health services. The aims of this work were to review guidelines/guidance for the prevention and management of TD from across the world which were compared with each other as were the TD guidelines compared to that for travel related and non-travel related acute diarrhoea for similarities and differences, with a focus on any relevant pharmacy legislation, needs assessments and training that may impact upon provision of travel health services by pharmacists focusing mainly on TD in adults. The PubMed, Google Scholar and Cochrane database were used to carry out an online search for publications on TD, acute diarrhoea and the guidance pharmacists have in the prevention and management of diarrhoea. The literature reviewed in this article indicates that where no specific guidelines/guidance existed, some pharmacists used the WHO guidelines (WHO), highlighting a need for local, regional and national evidence based guidelines in these countries.
The Creation of a Practice-Based Network of Pharmacists Working in Family Medicine Groups (FMG)
Authors: Maheu Anne , Vanier Marie-Claude , Rouleau Léonie , Dugré Nicolas , Guénette Line
Published: August 2019

A needs assessment study of pharmacists working in family medicine groups (FMG) demonstrated the necessity to build a practice-based network. This network would foster a faster integration into FMG and a more efficient collaborative practice. It would also take advantage of an existing practice-based research network (PBRN)—the STAT (Soutien Technologique pour l’Application et le Transfert des pratiques novatrices en pharmacie) network. A working group of nine FMG pharmacists from the different regions of the province of Quebec, Canada, and a committee of partners, including the key pharmacy organizations, were created. Between January 2018 and May 2019, nine meetings took place to discuss the needs assessment results and deploy an action plan. The practice-based network first year activities allowed identifying pharmacists working in FMGs across the province. A directory of these pharmacists was published on the STAT network. The vision, mission, mandate, name («Réseau Québécois des Pharmaciens GMF») and logo were developed. The first few activities include: Bi-monthly newsletters; a mentorship program; short evidence-based therapeutic letters (pharmacotherapeutic capsules) and a start-up kit to facilitate integration of these pharmacists. The Quebec FMG pharmacist practice-based network has been launched. It is planned to evaluate the members’ satisfaction in late Spring 2020 with regards to activities and resources provided.
Antioxidant, Antidiabetic, and Anticholinesterase Activities and Phytochemical Profile of Azorella glabra Wedd
Authors: Faraone Immacolata , Rai Dilip K. , Russo Daniela , Chiummiento Lucia , Fernandez Eloy , Choudhary Alka , Milella Luigi
Published: August 2019

Oxidative stress is involved in different diseases, such as diabetes and neurodegenerative diseases. The genus Azorella includes about 70 species of flowering plant species; most of them are commonly used as food and in particular as a tea infusion in the Andean region of South America in folk medicine to treat various chronic diseases. Azorella glabra Wedd. aerial parts were firstly analyzed for their in vitro antioxidant activity using different complementary assays. In particular, radical scavenging activity was tested against biological neutral radical DPPH; ferric reducing power and lipid peroxidation inhibitory capacity (FRAP and Beta-Carotene Bleaching tests) were also determined. The Relative Antioxidant Capacity Index (RACI) was used to compare data obtained by different assays. Then, the inhibitory ability of samples was investigated against α-amylase and α-glucosidase enzymes involved in diabetes and against acetylcholinesterase and butyrylcholinesterase enzymes considered as strategy for the treatment of Parkinson’s or Alzheimer’s diseases. Moreover, the phytochemical profile of the sample showing the highest RACI (1.35) and interesting enzymatic activities (IC50 of 163.54 ± 9.72 and 215.29 ± 17.10 μg/mL in α-glucosidase and acetylcholinesterase inhibition, respectively) was subjected to characterization and quantification of its phenolic composition using LC-MS/MS analysis. In fact, the ethyl acetate fraction derived from ethanol extract by liquid/liquid extraction showed 29 compounds, most of them are cinnamic acid derivatives, flavonoid derivatives, and a terpene. To the best of our knowledge, this is the first report about the evaluation of significant biological activities and phytochemical profile of A. glabra, an important source of health-promoting phytochemicals.
Steady-State Behavior and Endothelialization of a Silk-Based Small-Caliber Scaffold In Vivo Transplantation
Authors: Li Helei , Wang Yining , Sun Xiaolong , Tian Wei , Xu Jingjing , Wang Jiannan
Published: August 2019

A silk-based small-caliber tubular scaffold (SFTS), which is fabricated using a regenerated silk fibroin porous scaffold embedding a silk fabric core layer, has been proved to possess good cell compatibility and mechanical properties in vitro. In this study, the endothelialization ability and the steady-state blood flow of SFTSs were evaluated in vivo by implanting and replacing a common carotid artery in a rabbit. The results of the color doppler ultrasound and angiographies showed that the blood flow was circulated in the grafts without aneurysmal dilations or significant stenoses at any time point, and ran stronger and close to the autologous blood vessel from one month after implantation. The SFTSs presented an initial tridimensionality without being distorted or squashed. SEM and immunohistochemistry results showed that a clear and discontinuous endodermis appeared after one month of implantation; when implanted for three months, an endothelial layer fully covered the inner surface of SFTSs. RT-PCR results indicated that the gene expression level of CD31 in SFTSs was 45.8% and 75.3% by that of autologous blood vessels at 3 months and 12 months, respectively. The VEGF gene showed a high expression level that continued to increase after implantation.
High-Voltage Sulfolane Plasticized UV-Curable Gel Polymer Electrolyte
Authors: Wang Shiqi , Wei Chun , Ding Wenwen , Zou Linmin , Gong Yongyang , Liu Yuanli , Zang Limin , Xu Xu
Published: August 2019

A high-voltage electrolyte can match high-voltage positive electrode material to fully exert its capacity. In this research, a sulfolane plasticized polymer electrolyte was prepared by in situ photocuring. First, the effect of the sulfolane content on the ionic conductivity of the gel polymer electrolyte was investigated. Results showed that the ionic conductivity variation trend was in good agreement with the exponential function model for curve fitting. Second, the activation energy was calculated from the results of the variable temperature conductivity tests. The activation energy was inversely proportional to the sulfolane content. For the sulfolane content of 80 wt. % in gel polymer electrolyte (GPE)-80 (19.5 kJ/mol), the activation energy was close to conventional liquid electrolyte (9.5 kJ/mol), and the conductivity and electrochemical window were 0.64 mS/cm and 5.86 V, respectively. The battery cycle performance test showed that the initial specific discharge capacities of GPE-80 and liquid electrolyte were 176.8 and 148.3 mAh/g, respectively. After 80 cycles, the discharge capacities of GPE-80 and liquid electrolyte were 115.8 and 41.1 mAh/g, and the capacity retention rates were 65.5% and 27.7%, respectively; indicating that GPE-80 has a better specific discharge capacity and cycling performance than the liquid electrolyte. SEM images indicated that GPE-80 can suppress the growth of lithium dendrites. The EDS test showed that GPE-80 can inhibit the dissolution of metal ions in the cathode material.
One-Step Bark-Like Imitated Polypropylene (PP)/Polycarbonate (PC) Nanofibrous Meltblown Membrane for Efficient Particulate Matter Removal
Authors: Li Ting-Ting , Cen Xixi , Ren Hai-Tao , Sun Fei , Lin Qi , Lou Ching-Wen , Lin Jia-Horng
Published: August 2019

A bark-like imitated polypr opylene (PP)/polycarbonate (PC) nanofibrous membrane was constructed by one-step meltblown technique for efficient particulate matter (PM) removal. The effects of PC content (0%, 1%, 3%, 5%, and 7%) on membrane thermal stability, microscopic characteristics, filtration performance, hydrophilicity, and water vapor transmission were investigated. The results demonstrated that using facile design of incompatibility and viscosity difference between PC and PP polymers decreases average fiber diameter, creating a bark-like groove appearance and increasing surface potential, making a new PP/PC membrane with high filtration performance. The resultant PP/PC membrane had finer average fiber diameter of 0.63 μm, which was nearly 89.41% lower than PP membranes (5.95 μm), and its quality factor (0.036 Pa−1) was nearly 2.12 times than that of PP membranes (0.017 Pa−1) with the die hole diameter of 0.5 mm. This fabrication technique of a special meltblown filter membrane saves the cost of die retrofitting and post-processing, which provides an innovative method for particulate efficient removal of high efficient filters.
The “Original Position” as Public Performance: Liberalism, Pluralism, and Asceticism
Authors: Rivera Joseph
Published: August 2019

John Rawls’ well-known device of representation (his terminology) that he names the “original position” is put into play by the veil of ignorance. This imaginative device, found in both his early and late works, is often dismissed because it is misunderstood as an exercise in moral geometry. This essay discusses in more detail the subjective mechanics of the original position; while sympathetic of Rawls’ application of the veil of ignorance, I distinguish between a thick and thin veil, whereby I promote the latter. The final section makes a connection between the simulation of the original position and the religious practice of asceticism.
Optimal Risk Budgeting under a Finite Investment Horizon
Authors: López de Prado Marcos , Vince Ralph , Zhu Qiji Jim
Published: August 2019

The Growth-Optimal Portfolio (GOP) theory determines the path of bet sizes that maximize long-term wealth. This multi-horizon goal makes it more appealing among practitioners than myopic approaches, like Markowitz’s mean-variance or risk parity. The GOP literature typically considers risk-neutral investors with an infinite investment horizon. In this paper, we compute the optimal bet sizes in the more realistic setting of risk-averse investors with finite investment horizons. We find that, under this more realistic setting, the optimal bet sizes are considerably smaller than previously suggested by the GOP literature. We also develop quantitative methods for determining the risk-adjusted growth allocations (or risk budgeting) for a given finite investment horizon.
Estimating and Examining the Sensitivity of Different Vegetation Indices to Fractions of Vegetation Cover at Different Scaling Grids for Early Stage Acacia Plantation Forests Using a Fixed-Wing UAS
Authors: Iizuka Kotaro , Kato Tsuyoshi , Silsigia Sisva , Soufiningrum Alifia Yuni , Kozan Osamu
Published: August 2019

Understanding the information on land conditions and especially green vegetation cover is important for monitoring ecosystem dynamics. The fraction of vegetation cover (FVC) is a key variable that can be used to observe vegetation cover trends. Conventionally, satellite data are utilized to compute these variables, although computations in regions such as the tropics can limit the amount of available observation information due to frequent cloud coverage. Unmanned aerial systems (UASs) have become increasingly prominent in recent research and can remotely sense using the same methods as satellites but at a lower altitude. UASs are not limited by clouds and have a much higher resolution. This study utilizes a UAS to determine the emerging trends for FVC estimates at an industrial plantation site in Indonesia, which utilizes fast-growing Acacia trees that can rapidly change the land conditions. First, the UAS was utilized to collect high-resolution RGB imagery and multispectral images for the study area. The data were used to develop general land use/land cover (LULC) information for the site. Multispectral data were converted to various vegetation indices, and within the determined resolution grid (5, 10, 30 and 60 m), the fraction of each LULC type was analyzed for its correlation between the different vegetation indices (Vis). Finally, a simple empirical model was developed to estimate the FVC from the UAS data. The results show the correlation between the FVC (acacias) and different Vis ranging from R2 = 0.66–0.74, 0.76–0.8, 0.84–0.89 and 0.93–0.94 for 5, 10, 30 and 60 m grid resolutions, respectively. This study indicates that UAS-based FVC estimations can be used for observing fast-growing acacia trees at a fine scale resolution, which may assist current restoration programs in Indonesia.