bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparación de la evolución de los pacientes con gastrosquisis tratados con técnica Simil exit vs cierre primario
Authors: Lin Mei Chun , Acosta Farina Daniel , Oliveros Rivero Jorge , Pólit Guerrero Verónica , Argotti Zumbana Rodrigo , Andrade Montesdeoca Jimmy
Published: January 2024

Introducción: El tratamiento quirúrgico de la gastrosquisis involucra el cierre de la pared abdominal después de reducir los órganos intrabdominales. Se utiliza el método Simil-exit (SE) para disminuir la morbi-mortalidad. El objetivo del presente estudio fue comparar la evolución de los pacientes con gastrosquisis sometidos a la técnica SE frente a los tratados con cierre primario (CP).
Métodos: El presente estudio observacional, analiza registros de pacientes con gastrosquisis en el hospital "Dr. Roberto Gilbert Elizalde" del 2019 al 2022. Se comparan técnicas de SE Vs. CP. Las variables incluyen éxito del cierre, inicio de la alimentación enteral, duración de la estancia hospitalaria y mortalidad.
Resultados: Un total de 9 casos con SE y 26 casos con CP. No hubo diferencias entre el tiempo de inicio de la alimentación enteral (P=0.13), tiempo de hospitalización (P=0.43). Respecto a la mortalidad, en la técnica CP se reportaron 4 casos (15.4%; P=0.5), la misma que está en relación significativa con las reintervenciones (P=0.002) y las gastrosquisis complejas (P<0.001).
Conclusiones: El cierre con la técnica SE tiene una equivalencia de no inferioridad al respecto de la técnica de CP.
Alteraciones electroencefalográficas en niños con trastorno de déficit de atención e hiperactividad
Authors: Astudillo Mariño Nicolay , Santamaría Obando Doménica
Published: January 2024

Introducción: El trastorno del déficit de atención e hiperactividad (TDAH) es un trastorno del neurodesarrollo, que afecta el funcionamiento diario. Se investiga el potencial del video electroencefalograma (V-EEG) y el análisis de mapas de ritmos en el diagnóstico temprano del TDAH, particularmente en niños en riesgo. El objetivo del presente estudio fue evaluar las alteraciones electroencefalográficas en niños con TDAH.
Métodos: Se realizó un análisis retrospectivo en el Centro de Evaluación Neuropsicológica y Neuroterapia Avanzada (CENNA) en Quito-Ecuador, de enero a marzo de 2022, documentando características demográficas, uso del V-EEG y hallazgos en mapas de ritmos.
Resultados: La muestra incluyó 73 pacientes, edades entre 3 y 16 años, con 21.92 % mujeres y 78.08 % hombres. La edad promedio de 9 años. Todos se realizaron a V-EEG como parte de su evaluación revelando ondas lentas (rango delta) en el 30 % (n=22) de los pacientes. La región temporal bilateral fue la más afectada, observándose en el 63.64 % (n=14) de los casos con ondas lentas, seguida de las regiones frontal 18.18 % (n=4), occipital 9.09 % (n=2), frontotemporal 4 55 % (n=1) y parietal 4.55 % (n=1).
Conclusiones: Los hallazgos sugieren que el V-EEG, mostrando ondas lentas en regiones temporales bilaterales, puede ser una herramienta útil como biomarcador para el diagnóstico del TDAH. Estos resultados indican la necesidad de más investigaciones para confirmar estos hallazgos y establecer la validez y utilidad clínica del V-EEG en el TDAH.
Características transfusionales y hemovigilancia de los pacientes pediátricos con cáncer
Authors: Urdiales Valarezo Adriana Inés , Guerrero Quiroz Enmanuel Isidoro
Published: January 2024

Introducción: La terapia transfusional no está libre de riesgos, siendo los pacientes hemato- oncológicos los mayores transfundidos, por ello la necesidad de la hemovigilancia. El objetivo del presente estudio fue identificar las características transfusionales y la hemovigilancia de los pacientes pediátricos con cáncer en el Instituto SOLCA-Cuenca, enero-diciembre 2021.

Método: Se realizó un estudio descriptivo con todos los pacientes menores de 18 años que requirieron transfusiones y todas las hemotransfusiones realizadas en SOLCA-Cuenca 2021. Los datos fueron recolectados en un formulario previamente validado y se analizaron en el programa SPSS v25.0, presentándose como frecuencias, porcentajes, media y desviación estándar.

Resultados: Se estudiaron 73 pacientes y 620 transfusiones, predominando: adolescentes (45.2 %), de sexo masculino (63 %), mestizos (98.6 %), urbanos (76.7%), grupo ORH+ (83.5 %). Con leucemia linfoblástica aguda células B (49.3 %) y quimioterapia de inducción (41.1 %). El 58.9 % tenían antecedente transfusional y 4.1 % reacción previa (urticaria). La media transfusional por paciente fue 8,49 y, 7,1% fueron premedicadas con esteroides; se transfundieron principalmente concentrados eritrocitarios (49%) por anemia (95.4 %) a 9,32ml/kg (media) en 121 a 180 minutos (56.9 %). Del 3.1 % de reacciones evidenciadas, el 100% fueron inmediatas, no infecciosas (urticaria 84.2 %), definitivas y se trataron con medicamentos (84.2 % esteroide); el 79 % de reacciones fueron leves; fueron secundarias a concentrados eritrocitarios (47.4 %), aféresis (47.4 %) y; evidenciadas en pacientes con leucemia linfoblástica aguda células B (31.5 %).

Conclusiones: Los pacientes con leucemia linfoblástica aguda células B requirieron más transfusiones sanguíneas, principalmente concentrados eritrocitarios; mientras las reacciones transfusionales se asociaron frecuentemente a concentrados eritrocitarios y aféresis.
UPAYA MENINGKATKAN AKTIVITAS DAN HASIL BELAJAR BAHASA INGGRIS MELALUI PENERAPAN TEKNIK JIGSAW
Authors: Hakim Lukman
Published: January 2024

Tujuan Penelitian ini adalah untuk mengetahui Pengaruh penerapan tehnik Jigsaw dalam meningkatkan aktifitas dan hasil belajar bahasa Inggris di kelas VII SMP Muhammadiyah 27 Paciran tahun pelajaran 2021/2022. Penelitian ini merupakan Penelitian Tindakan Kelas dengan subyek penelitian adalah siswa kelas VII SMP Muhammadiyah 27 Paciran tahun pelajaran 20201/2022. Penelitian ini dilaksanakan selama 2 (dua) siklus dimana setiap siklusnya terdiri dari : Perencanaan, Pelaksanaan, Pengamatan dan Refleksi, sedangkan instrumen yang digunakan dalam penelitian ini meliputi : Data aktifitas siswa melalui pengamatan, Data nilai siswa, dan Data angket yang merupakan tanggapan siswa. Data penelitian menunjukkan bahwa dengan tehnik Jigsaw dapat meningkatkan aktivitas dan hasil belajar bahasa Inggris.
HUBUNGAN TINGGI BADAN DAN BERAT BADAN TERHADAP KECEPATAN RENANG GAYA DADA 50 M PADA ATLET RENANG PRESTASI CLUB JUNIOR AQUATIC SPORT (JAS) KAB GARUT
Authors: Saadah Siti , Hermawan Irwan , Kosasih Alam Hadi , Arifin Z. , Sonjaya Azhar Ramadhana
Published: January 2024

Renang merupakan salah satu cabang olahraga yang cukup dikenal diseluruh lapisan masyarakat, baik dikalangan anak-anak sampai orang dewasa. Renang adalah olahraga yang dilakukan di udara, dengan cara menggerakkan bagian badan, mengapung di udara dan seluruh bagian badan bergerak dengan bebas. Jenis penelitian ini adalah penelitian Korelasional. Dalam penelitian ini yang menjadi variabel bebas Tinggi Badan, ( X1 ), dan Berat Badan ( X2 ) dan variabel terikat kecepatan renang 50 meter gaya bebas (Y).  Jumlah sampel 17 orang Atlit Club Junior Aquatik Sport ( Jas ) Kab Garut.  Kesimpulannya sangat signifikan yang berarti ada hubungan antara tinggi badan terhadap kecepatan renang gaya dada 50M dan dari hasil perhitungan variabel Berat Badan terhadap kecepatan renang gaya Dada 50M pada Atlit Renang Junior Aquatik Sport JAS. Diperoleh nilai rhitung rtabel sebesar 617922, kesimpulannya sangat signifikan yang berarti ada hubungan antara berat badan terhadap kecepatan renang gaya Dada 50M.
Analysis of State-of-the-art Software Solutions for Unstructured Outdoor Environment Perception in Goal-oriented Navigation of Off-road Unmanned Ground Vehicles
Authors: Vargovčík Matej
Published: January 2024

This paper presents a comprehensive analysis of state-of-the-art software solutions designed for the perception of unstructured outdoor environments, with a focus on their applicability in goal-oriented navigation for off-road unmanned ground vehicles (UGVs). The analysis encompasses the evaluation of various sensors for UGV navigation, comparison of methods for extracting perceptual information from sensor data, and the development of a perception system based on the findings. The proposed system leverages advancements in simultaneous localization and mapping (SLAM), visual odometry, and traversability segmentation using 3D LiDAR and visual systems. The analysis suggests a phased approach for the development of autonomous navigation, where the initial phase relies on complex SLAM and teleoperation assistance, and the subsequent phase introduces an autonomous mode utilizing semantical terrain representation.
Invigorasi Larutan Bawang Merah Terhadap Viabilitas dan Vigor Tiga Benih Padi Varietas Lokal
Authors: Suparto Hairu , Sofyan Antar , Irfan Muhammad
Published: January 2024

Rice production in South Kalimantan during January to September 2020 decreased compared to 2019. The use of rice seeds per hectare  is generally still not in accordance with the recommendations. The local varieties of rice seeds that cultivated are from last year's cropping season, where storage was not good which could lead to a decrease in seed quality. Shallots  contain  hormones auxin and gibberellins, can be used as a natural growth regulator. This study used a solution of shallots on three local varieties of rice seeds. The purpose of this study was to provide information on the use of natural growth regulators in shallot solution as an alternative to increase seed viability to become a provider of quality seeds. This research carried out from October to November 2021 at the Production Laboratory of the Department of Agroecotechnology, Faculty of Agriculture, Lambung Mangkurat University. The implementation of the research is making shallot stock solution, seed preparation, seed soaking, seed germination, and maintenance. The method used was qualitative using single factor Completely Randomized Design  with three levels of treatment and each treatment consisted of five replications. The results showed that treatment using onion solution invigoration had a significant effects on the parameters of growth uniformity and maximum growth potential of expired local rice seeds of Siam Banjar variety. The highest growth speed and seed germination were found in Siam Saba variety. The highest growth uniformity was found in Siam Unus variety. The highest maximum growth potential is found in  Siam Mutiara variety.
Una bambina molto in gamba...: alla ricerca del suo dolore
Authors: Mambelli Lorenzo , Gagliardo Beatrice , Minguzzi Mariateresa , Marchetti Federico
Published: January 2024

Osteoid osteoma is a condition that causes pain and limping in the lower extremity. The- refore, a thorough investigation is necessary in preschool children with prolonged pain and limping. The paper presents the case of a 6-year-old girl with severe nocturnal pain in her tibia. X-ray and MRI did not show any abnormalities, but a technetium bone scan revealed an osteoid osteoma in her femoral neck. CT scan confirmed the diagnosis. The patient underwent ablative treatment with focused ultrasound guided by MRI. When osteoid osteoma is suspected, standard radiology should be the initial diagnostic ima- ging. However, it is important to extend the imaging to the entire femur if the pain radia- tes from the femur to the leg. If the standard x-ray is inconclusive, a CT scan or techne- tium bone scan should be considered.
Un vomito di troppo, un'evacuazione di meno
Authors: Cerreti Micaela
Published: January 2024

A typical case of a hypertrophic pyloric stenosis is presented and discussed.
Crampi muscolari, ipercpkemia e fenomeno "Second wind": la malattia di McArdle
Authors: Faraguna Martha Caterina , Barzaghi Silvia , Crescitelli Viola , Pretese Roberta , Fornari Anna , Gasperini Serena
Published: January 2024

The case of a 12-year-old girl presenting with poor exercise tolerance, muscular cramps and CPK high levels is described.The diagnosis of McArdle disease was eventually made due to the classic “second wind” sign.
Public spirit and compassion fatigue
Authors: Lykkegaard Sønderkær Trine
Published: January 2024

This paper discusses the concept of compassion fatigue in light of the importance that political decisions, especially the application of the concept of public spirit, have had on care and nursing in a Danish hospital context during the COVID-19 pandemic. The paper is based on recent research literature in the field as well as the author’s own participatory observation study. The paper suggests that nurses already show a sense of public spirit due to their authorization and professional ethics, but at the same time they must balance the ambiguity of nursing care. A linguistic-philosophical study of public spirit shows that the concept can have a discursive, double-binding and interpellative effect on nurses, who may therefore have an experience of inadequacy and compassion fatigue. In this context, compassion fatigue must be understood as the fact that nurses cannot provide the care they want or that is expected of them. Public spirit can be said to have had a renaissance and linguistic and moral supremacy during the COVID-19 pandemic. The paper views the concept of waywardness1 as a possible response for how to prevent or completely avoid compassion fatigue, so that nurses instead have an experience of compassion / self-compassion. This could in the end be important for encouraging more nursing students and nurses who have the desire and opportunity to stay in the profession.
Keywords: Nursing care, compassion fatigue, public spirit, compassion, COVID-19 pandemic
Rezension von: Wiesflecker, Hermann, Kaiser Maximilian I., Bd. 1 + 2
Authors: Wunder Gerd , Wiesflecker Hermann
Published: January 2024

Hermann Wiesflecker: Kaiser Maximilianl. München: Oldenbourg. Bd. 1, 1977, 622 S.; Bd. 2, 1981, 691 S.
Rezension von: Henning, Eckart, Die gefürstete Grafschaft Henneberg-Schleusingen im Zeitalter der Reformation
Authors: Wunder Gerd , Henning Eckart
Published: January 2024

Eckart Henning: Die gefürstete Grafschaft Henneberg-Schleusingen im Zeitalter der Reformation. (= Mitteldeutsche Forschungen, 88). Köln, Wien: Böhlau 1981. XI, 283 S.
Rezension von: Bosch, Michael u.a. (Hrsg.), Der Widerstand im deutschen Südwesten 1933-1945
Authors: König Hans-Joachim , Bosch Michael
Published: January 2024

Der Widerstand im deutschen Südwesten 1933-1945. Hrsg. von Michael Bosch und Wolfgang Niess. (= Schriften zur politischen Landeskunde Baden-Württembergs, 10). Stuttgart, Berlin, Köln, Mainz: Kohlhammer 1984. 343 S.
Rezension von: Küther, Carsten, Menschen auf der Straße
Authors: Müller Hans Peter , Küther Carsten
Published: January 2024

Carsten Küther: Menschen auf der Straße. Vagierende Unterschichten in Bayern, Franken und Schwaben in der zweiten Hälfte des 18. Jahrhunderts. (= Kritische Studien zur Geschichtswissenschaft, 56). Göttingen: Vandenhoeck und Ruprecht 1983. 173 S.
Rezension von: von Freeden, Max H., Die Schönbornzeit
Authors: Göpfert Eberhard , Freeden Max H. von
Published: January 2024

MaxH. von Freeden: Die Schönbornzeit, "... aus Frankens besseren Tagen..." (= Mainfränkische Hefte, 80). Würzburg 1983. 175 S. u. Abb.
Rezension von: Arens, Fritz, Der Dom zu Mainz
Authors: Grünenwald Elisabeth , Arens Fritz
Published: January 2024

Fritz Arens: Der Dom zu Mainz. Darmstadt: Wissenschaftliche Buchgesellschaft 1982. 62 Abb., 1 Grundriß des Domes.
Rezension von: Fiege, Gertrud (Hrsg.), Bildnisse
Authors: Grünenwald Elisabeth , Fiege Gertrud
Published: January 2024

Bildnisse. Verzeichnis der Plastiken, Gemälde, Handzeichnungen, Scherenschnitte im Schiller-Nationalmuseum und Deutschen Literaturarchiv Marbach. In Zusammenarb. mit Albrecht Bergold von Gertrud Fiege. Band 1: A-L. Band 2: M-Z. (= Deutsches Literaturarchiv. Verzeichnisse, Berichte, Informationen, 3 u. 4). Marbach: Deutsche Schillergesellschaft 1978. 103, 116 S.
Rezension von: Hotz, Walter, Pfalzen und Burgen der Stauferzeit
Authors: Grünenwald Elisabeth , Hotz Walter
Published: January 2024

Walter Hotz: Pfalzen und Burgen der Stauferzeit. Geschichte und Gestalt. Darmstadt: Wissenschaftliche Buchgesellschaft 1981. 360 S., 208 Abb.
Rezension von: Kissling, Hermann, Kunst im Städtischen Museum Schwäbisch Gmünd
Authors: Grünenwald Elisabeth , Kissling Hermann
Published: January 2024

Hermann Kissling: Kunst im Städtischen Museum Schwäbisch Gmünd. Schwäbisch Gmünd: Gmünder Geschichtsverein 1979. 127 S., 70 Abb. davon 11 in Farbe.
Rezension von: Einsle, Hans, Baden-Württemberg von A-Z
Authors: König Hans-Joachim , Einsle Hans
Published: January 2024

Hans Einsle: Baden-Württemberg von A-Z in Geschichte, Kultur, Kunst, Brauchtum, Landschaft und anderen liebenswerten Dingen. Tübingen und Basel: Erdmann 1979. 360 S., 219 Abb.
Rezension von: Risch, Izhak, Megillath Mishpachtenu
Authors: Ulshöfer Kuno , Risch Izhak
Published: January 2024

Izhak Risch: Megillath Mishpachtenu. Records conceming the ancestry of the Levi, Berlinger and Ellinger families of the Zvi branch (in Ivrit). Haifa 1974. 88 S.
Rezension von: Bomm, Helmut (Hrsg.), 100 Jahre Heimat- und Kunstverein Backnang
Authors: Wunder Gerd , Bomm Helmut
Published: January 2024

Vom Altertumsverein zum Heimat- und Kunstverein. 100 Jahre Heimat- und Kunstverein Backnang. (= Schriftenreihe des Heimat- und Kunstvereins Backnang, 4). 176 S. Ill.
Rezension von: Dienel, Werner Martin, Crailsheim einst und heute
Authors: Pastor Egil , Dienel Werner Martin
Published: January 2024

Werner Martin Dienel: Crailsheim einst und heute. Zehn mal zehn Jahre Geschichte der fränkischen Stadt an der Jagst. Hrsg. zum 100jährigen Bestehen der Kreissparkasse Crailsheim 1884-1984. Kirchberg: Wettin-Verlag 1984. 119 S., 84 Abb.
Rezension von: Akermann, Manfred (Hrsg.), 75 Jahre Heimat- und Altertumsverein Heidenheim
Authors: Wunder Gerd , Akermann Manfred
Published: January 2024

75 Jahre Heimat- und Altertumsverein Heidenheim 1901-1976. Heidenheim 1976. 273 S., Ill.
A case of primary squamous cell carcinoma of the parotid gland and review of the literature
Authors: Zhao Jingli , Nan Xinrong , Zhou Chuhuan , Jiang Nan , Tian Liangliang
Published: January 2024

Introduction: Primary parotid squamous cell carcinoma (PPSCC) is a rare malignant epithelial tumor originating in the parotid gland with complex diagnostic procedures and a poor prognosis. The etiology, tissue origin, and biological behavior of the disease are currently unknown due to its underreporting. It is crucial to differentiate this type of squamous cell carcinoma (SCC) of the parotid gland from other salivary gland tumors because of its widespread invasiveness, which leads to high mortality.

Case Report: This article reports a case of a 62-year-old male patient in whom histopathological examination confirmed that the tumor was squamous cell carcinoma. Since the patient had no other main source, the ultimate diagnosis was the primary SCC of the parotid gland. The patient is currently receiving routine follow-up care and has shown no signs of recurrence.

Conclusion: In conclusion, even asymptomatic individuals should be highly regarded to prevent mistakes because the diagnostic process for this disease is complicated. The presence of metastatic cancer should be ruled out, and histology and immunohistochemistry should be used to confirm the diagnosis.
VALUE-ADDED PRODUCTS OF GARLIC AND THEIR POTENTIAL HEALTH BENEFITS - A REVIEW
Authors: KAUR TARANPREET , RAWAT MONISHA , KATHAYAT KHUSHBOO
Published: January 2024

– Garlic and its different value-added products are widely employed in food and pharmaceutical industries in a variety of forms due to its distinct flavour. It is processed into dehydrated garlic flakes, garlic slices or rings, garlic grits, garlic tablets, garlic pickles, garlic powder, digestive churns, paste, garlic oil, salts which are mostly demanded at national as well as international market due to its nutritional composition, health benefits and medicinal properties. The presence of various biologically active compounds in garlic has attracted the attention of modern medicine because of its effects in maintaining good health it reduces cholesterol, boosts the immune system, prevents from various ailments such as cancer, cardiovascular diseases, metabolic disorders, blood pressure, and diabetes, through its anti-inflammatory, antioxidant, and lipid-lowering properties. Value addition of garlic in the form of various processed products will significantly increase the export of garlic and its value-added products and will also play an important role to augment the expanding garlic-based processing industries in India.
EVALUATING THE INFLUENCE OF VARIED SYNTHETIC FERTILIZER CONCENTRATIONS IN CONJUNCTION WITH VERMICOMPOST AND FYM ON THE GROWTH, YIELD, AND ECONOMIC ASPECTS OF BLACK GRAM (Vigna mungo) CULTIVATION IN THE DEHRADUN REGION OF UTTARAKHAND
Authors: GUDLA SRI LIKHITHA , VARIKUPPALA MANISHA , DEVARAKONDA NIKHITHA , RAY SUMIT
Published: January 2024

– To explore the effects of vermicompost, farmyard manure (FYM), and synthetic fertilizers on the growth, yield, and economics of black gram cultivation, a field experiment was conducted during the summer season of 2019-20 at the Research Block of Uttaranchal University in Dehradun, Uttarakhand. The experimental layout followed an incomplete randomized block design featuring ten treatments and three replications. The findings highlighted that among all the treatments, Treatment T10, which consisted of 75% Vermicompost, 50% FYM, and 50% recommended dose of fertilizer (RDF), emerged as the most favourable option from the farmer’s perspective. It exhibited notable improvements in various parameters, including plant height (58.67 cm), straw yield (80 q/ha), the number of pods per plant (69), and grain yield (15.023 quintals per hectare) at harvest. Furthermore, Treatment T10 also yielded a commendable net return of 88,215.65 Rs per hectare, which is economically advantageous for farmers. Based on the results of this study, it can be concluded that the combination of 75% Vermicompost, 50% FYM, and 50% RDF significantly enhances the growth, yield, and overall economic viability of black gram cultivation, especially in the agroclimatic conditions of Dehradun
ANTIMICROBIAL ACTIVITY OF IPOMEA CARNEA LEAVES
Authors: KAUR GILL PUSHPDEEP , CHEREKAR MAKARAND N.
Published: January 2024

Bioprospecting is a systematic and organized search for useful natural products derived from bioresources including plants, animals and microorganisms. These are potential sources of novel chemical and biological products for medicine, agriculture, and other industries. The aim of this work was to check bioprospecting of Ipomoea carnea Jacq plant. Extract of Ipomoea carnea Jacq plant was searched for novel therapeutic compounds. Its extract was used to kill the pest, weeds and unwanted plants. It also preserves soil fertility and helps in bio composting and anti-microbial agent. Ipomoea carnea plant has positive and negative effects on antimicrobial properties, crude ethanol extract elucidate prominent antimicrobial activity against Pseudomonous auroginosa and Bacillus subtilis
ESTABLISHMENT OF A BIOINFORMATICS PIPELINE FOR THE DETECTION OF PATHOGENIC BACTERIA
Authors: R.W.P.M. RAJAPAKSHA , K.2 VIVEHANANTHAN , D.P.S.T.G ATTANAYAKA
Published: January 2024

Next-generation sequencing-based methods using partial 16S rRNA gene amplicons are extensively applied today in studies of the plant metagenomes. NGS sequencing creates huge sets of raw data making analysis a challenging task. Lack of computational and bioinformatics knowledge and tools for analyzing high throughput data to interpret correct biological variations is a major problem. In addition, downstream analysis of NGS data with the available bioinformatics platforms create various challenges in inferring microbial composition. The available commercial software are expensive and individual opensource tools are usually operate stand alone as they are not combined for a user-friendly workflow. Therefore, beginners in bioinformatics might find analysis procedures are complicated, expensive, and timeconsuming with the associated learning. In the present study, a bioinformatics pipeline is developed to analyze the 16S rDNA amplicons of plant metagenome. Microbial DNA was extracted from imported seed potato tubers. Extracted DNA was sequenced using Ion Torrent Next Generation Sequencing technology by amplifying 400 bp V1-V2 region of 16S rRNA gene for the detection of bacterial pathogens. The pipeline was built by stringing together many command line tools; Quality checking of raw fastq data using FastQC, trimming of low-quality data with Trimmomatric, alignment of trimmed data using the BWA-MEM algorithm, removal of duplicate reads with Picard Mark Duplicates tool and finally generation of the phylogenetic tree and taxonomic profile with MEGAN 5. The developed pipeline was used to analyze the 16S rRNA next generation sequences and the reliability of the results has been checked with the use of mock communities for validation. The pipeline often can be executed on laptop sized machines to obtain the output in a couple of hours enabling easy access for the researchers.
Manifestação clínica atípica de infecção por Hepatozoon spp. em cadela no Brasil
Authors: Alves Jacqueline Nascimento , Magnino Chaban Núbia , Rezende Rodrigo Supranzetti de , Martin Ian , Bittar Joely Ferreira Figueiredo , Alves Endrigo Gabellini Leonel , Rosado Isabel Rodrigues
Published: January 2024

A hepatozoonose canina é uma hemoparasitose que é transmitido ao cão por meio da ingestão de carrapatos contendo as formas patogênicas. Duas espécies são incriminadas pela doença: o Hepatozoon canis e o Hepatozoon americanum, sendo, no Brasil, a prevalência dessa segunda espécie ainda desconhecida. O presente trabalho tem como objetivo relatar um caso de infecção por Hepatozoon spp com acometimento dos sistemas nervoso central, muscular e reprodutivo. Foi atendida uma cadela SRD, adulta, com queixa principal de aborto, que evoluiu para febre intermitente, miosite e sinais neurológicos característicos de encefalite. Nos exames laboratoriais foram encontrados anemia, leucocitose, hiperglobulinemia, e observadas inclusões em leucócitos compatíveis com Hepatozoon spp, confirmado por PCR. O tratamento inicial foi instituído com doxiciclina e diproprionato de imidocarb. Posteriormente, acrescentou-se clindamicina, sulfametoxazol e trimetropima, com melhora dos sinais clínicos até a recuperação. Dessa forma, suspeita se tratar de um caso de H. americanum ou de uma nova sintomatologia causada por H. canis. Conclui-se que é necessário que sejam realizados identificação das espécies ditribuídas na região.
Síntese de pontos quânticos de carbono (PQC) de biomassa via rota hidrotérmica: Uma revisão sistemática
Authors: Simões Alexandre Rodrigues , De Souza Alexandre Teixeira , Meurer Eduardo César , Oliveira Évelin Lemos de , Scaliante Mara Heloisa Neves Olsen
Published: January 2024

Os pontos quânticos de carbono estão sendo aplicados em várias áreas de tecnologia, devido às suas propriedades, como tamanho nanométrico, fotoluminescência e aos grupos funcionais presentes na superfície. Esta revisão sistemática teve como objetivo analisar o método hidrotérmico e a sua relação entre os parâmetros de síntese do PQC, envolvendo diferentes tipos de biomassa e condições de operação, como temperatura e tempo. A revisão sistemática foi realizada na base de dados ScienceDirect, identificando os principais artigos que sintetizaram os PQC a partir de biomassa vegetal. Foi feito um levantamento de 84 artigos encontrados, 16 atenderam aos parâmetros de inclusão. A maioria dos autores caracterizaram os PQC utilizando de diferentes técnicas. Os resultados mostraram que os PQC sintetizados pelo método hidrotérmico, apresentaram aplicações nas áreas de biomagem, detecção, sensores de pH, fotocatálise, fitoremediação, inibição de corrosão e terapia fotodinâmica.
The Direct and Indirect Influence of Price Fairness, Food Quality, and Word-of-Mouth on Purchase Intention: The Role of Brand Image (A Case of Mixue)
Authors: Putri Safir Dzakiyyah Aziziyah
Published: January 2024

Purchase intention holds significant importance in understanding factors that drive customers’ decision-making processes and subsequent purchasing behavior, using Mixue as a case study, this study focuses on the purchase intention of Mixue by exploring determinants such price fairness, food quality and word-of-mouth and the indirect effect of brand image. The study was conducted in Jakarta with a total of 206 samples which were analyzed using the Smart-PLS software. The results indicated that food quality and word-of-mouth have a positive significant influence on purchase intention and that price fairness does not. Additionally, the relationship between the determinants is mediated by brand image. This study contributes to the existing literature on purchase intention by providing empirical evidence on Mixue and emphasizes the importance of enhancing food quality, fostering positive word-of-mouth recommendations, and strengthening brand image in hopes of providing valuable insights for Mixue management for developing effective marketing strategies.
Ensino de história e natureza: vivências históricas no Serrote do Coati, em Cachoeira dos Índios – PB
Authors: Dantas Djalma Luiz do Nascimento , Dos Santos Joaquim
Published: January 2024

O presente artigo busca articular a relação entre o Ensino de História e a Educação Patrimonial como ferramenta fecunda para a construção da Consciência Histórica. Neste sentido, o trabalho apresenta a experiência prática de utilizar o Patrimônio Natural, a Memória Social reivindicada pela História oral nas aulas de História no município de Cachoeira dos Índios -PB. Como ponto chave deste trabalho, os discentes são desafiados a buscar conhecimento dos bens patrimoniais do lugar. Na ocasião, o bem escolhido para as ações do projeto de ação educacional Akangatu foi o Serrote do Coati, devido a sua paisagem poder ser contemplada a partir do entorno da escola. Para além disso, a expedição de ida ao lugar possibilitou a vivência histórica, a aula passeio se torna o lugar onde a história se encontra com as memórias do passado e do presente, construídas a cada passo na trilha rumo ao topo do Serrote, consolidando o conhecimento histórico e a ideia do patrimônio natural para o fortalecimento de pertencimento de sujeitos históricos.
Thermoregulation of stingless bee colonies in boxes for rationale breeding in the Center-West of the state of Maranhão
Authors: Caldas Rayssa Silva , Pacheco Weverton Filgueira , Pacheco Thais Valéria Souza Silva , Pegorini Reysi Jhayne , Da Silva Filho Florisval Protasio , Damasceno Josilda Cavalcante Amorim , Moreira Gabriela Luz Pereira , Moreira Eduardo de Souza
Published: January 2024

Indigenous stingless bees of the subfamily Meliponinae are recognized as bees native to Brazil. They have an atrophied sting and are widely distributed throughout tropical regions, from Mexico to the south of Brazil on the American Continent. This study was carried out to evaluate the thermoregulatory behavior in colonies of stingless bees allocated in rational breeding boxes in the municipality of Grajaú, Central West region of the state of Maranhão. The project was developed at the IFMA Grajaú Campus, where two models of rational breeding boxes for stingless bees were made to evaluate which of the models has greater colonial development of two species of bees (Melipona fasciculata and Melipona flavolineata) when transferred from the native nests to the rational breeding boxes. To this end, digital thermometers were installed in stingless bee hives and thermo-hygrometers to monitor the maximum and minimum daily temperature for six months. Despite a wide variation in maximum and minimum external temperatures, the bees managed to maintain the temperature between 23.5º and 33.9ºC and the relative humidity between 39 and 64% inside the hives throughout the days, especially the hives in model 1. This was the most adapted prototype for rearing bees in this experiment, with good thermoregulation of stingless bee colonies throughout the day in both species over the study months.
Homeschooling: para que(m)? Reflexões sobre a (d)escolarização da classe trabalhadora
Authors: Costa Telma Ferreira Farias Teles
Published: January 2024

Este texto, estruturado como um ensaio teórico, explora as motivações e especula sobre as implicações da legislação de ensino domiciliar no Brasil. Problematiza-se a viabilidade desse formato educacional para a classe trabalhadora e seus desdobramentos, buscando refletir sobre a possível segregação entre classes. Trabalha-se com a hipótese de que a prática de ensino domiciliar, conforme proposta, se alinha com a racionalidade neoliberal do bloco no poder brasileiro, que se empenha em perpetuar, atualizando, os mecanismos de exclusão, particularmente ao legitimar a segregação social em grupos educacionais. Se aprovada a lei, a distribuição de oportunidades e, possivelmente, até direitos poderiam ser limitados segundo critérios de acesso a modelos educacionais específicos, sendo o homeschooling, portanto, um mecanismo de contrarrevolução preventiva e continuidade da exclusão social, harmonizado aos interesses do capital globalizado e dos setores conservadores. Ao concluir, retomam-se os principais argumentos ponderados e reflete-se sobre a possibilidade de validar a hipótese aventada.
Explorando a temática dos plásticos: abordagens interdisciplinares e soluções sustentáveis na disciplina de Projetos Integradores
Authors: Acácio Regina da Silva , Santos Wagner Max Alves , Da Silva Djanete Ferreira , Goulart Henrique Fonseca , Santana Antônio Euzébio Goulart
Published: January 2024

O artigo enfatiza o protagonismo estudantil e os Projetos Integradores no Programa Alagoano de Ensino Integral (pALei), relacionados à BNCC. O objetivo é conscientizar os alunos sobre os impactos ambientais relacionados ao consumo excessivo e descarte inapropriado de plásticos, e estimulá-los a encontrar soluções sustentáveis. A metodologia envolveu uma turma de alunos do Ensino Médio Integral, que escolheu o tema "Plásticos e seus impactos ambientais". A partir de atividades práticas, como criação de brinquedos reciclados e um jardim vertical com garrafas PET, engajaram os alunos. Os resultados destacam a importância do protagonismo para uma educação centrada no aluno, desenvolvendo habilidades socioemocionais. A abordagem prática permitiu que os alunos aprendessem sobre os impactos dos plásticos e criassem soluções, como o plástico biodegradável a partir do amido, além de envolverem-se ativamente no processo de conscientização da comunidade. O artigo destaca a importância do protagonismo estudantil através dos Projetos Integradores, focados na temática dos plásticos e seus impactos ambientais, como forma de promover o aprendizado interdisciplinar e o engajamento dos alunos em questões relevantes para a sociedade.
Os cirurgiões-dentistas brasileiros estão preparados para lidar com urgências e emergências médicas?
Authors: Santos Filho Hélio Aparecido , Rocha Natália Cristina , De Almeida-Silva Luis Augusto , Lupp Juliana dos Santos , Costa Thayna Isabele Stopiello , Amorim José Benedito Oliveira
Published: January 2024

A interconexão entre saúde bucal e sistêmica ressalta a importância do cirurgião-dentista (CD) em compreender não apenas as implicações locais, mas também as sistêmicas de suas intervenções. A crescente conscientização da sociedade sobre a relevância da saúde bucal, associada aos avanços médicos, resultou em uma diversidade de pacientes idosos e portadores de doenças sistêmicas. Apesar dos benefícios, o atendimento a pacientes mais vulneráveis expõe os CDs à possibilidade de ocorrência de urgências e emergências médicas (UEMs), para as quais muitos não se sentem preparados. Com o intuito de identificar o nível de aptidão dos CDs brasileiros em lidar com UEMs, este estudo realizou uma revisão integrativa da literatura, por meio de pesquisas nas bases de dados PubMed, Scielo e Google Acadêmico, utilizando descritores indexados e diferentes estratégias de busca. Dos 2.039 profissionais avaliados, apenas 39% demonstraram aptidão, embora a ocorrência de UEMs tenha sido relatada por 47,5% dos profissionais, sendo a síncope a situação mais prevalente. Os resultados revelaram que os CDs brasileiros não estão preparados para lidar com UEMs. A falta de preparo destaca a urgência de intervenções, enfatizando a necessidade de reformulações nas políticas educacionais, incluindo a inserção de treinamentos específicos, revisão constante dos conhecimentos e uma formação abrangente e contínua, garantindo não apenas habilidades técnicas, mas também a segurança e a saúde dos pacientes.
A Network Intrusion Detection Method Based on a Fast KNN Algorithm
Authors: He Pengcheng , Feng Guifeng , Li Huixu , Yang Le
Published: January 2024

This paper proposes a network intrusion detection method based on fast KNN algorithm. First, continuous data discretization processing and character data digitization processing are performed on the original data. Then the feature reduction algorithm based on mutual information is used to reduce the features of the preprocessed data. Finally, the fast KNN algorithm is used to classify and detect the feature-reduced data, and the classification results are output. The above method was verified on the KDD CUP99 data set and compared with existing technologies. The method proposed in this article clearly has the advantages of high classification efficiency and classification accuracy.
The Applications of Genome Editing in the Management of Cancer: A Narrative Overview
Authors: Al-Janabi Ismail Ibrahim
Published: January 2024

Objective: To provide an overview of the status of applying genome editing, particularly CRISPR/Cas9, in the management of cancer. Method: Several search tools were consulted in the preparation of this manuscript to obtain peer-reviewed articles using the given evaluation and selection criteria. Main points: CRISPR/Cas9 and its associated variants stood out as the technology of choice for manipulating cancer cells and managing the disease. This genome-editing technology can positively contribute to the elucidation of the roles of cancer genes, establish animal models to study the disease, and therapeutically empower the development of next-generation immunotherapies. Conclusions: The manipulation of the human genome using CRISPR/Cas9 to treat cancer has only recently begun. Several clinical trials are ongoing, and the results are eagerly awaited. In the meantime, improvements and advancements in genome editing are being developed at a rapid pace to take advantage of this evolving technology.
THE CURRENT CRISIS STAGE OF CIVILIZATIONAL DYNAMICS OF MANKIND
Authors: Nersisyan A
Published: January 2024

The content of the research problem we have put forward in the article
concerns the cyclical dynamics of mankind and its modern crisis milestone.
The observation of the process and the deep nature of the formation of the
latter summarizes the purpose of this study.
The relevance of the problem is dictated by the objective requirement to
disclose the deep basis of the crisis manifestations of modern realities.
In accordance with the purpose of the study, a number of interconnected
research problems were put set forward and solved: theoretical approaches to
the cyclical dynamics of civilizations were generalized, the characteristics of
their crisis milestones were analyzed which are displayed in the context of
modern civilizational realities.
To solve the research problems, we used scientific methods of analysis,
synthesis, dipping and reengineering, comparative and geographical,
theoretical generalization.
The theoretical conclusions and proposals obtained from the study can
provoke the necessary scientific debate both in the academic theoretical field
and become the basis for practical prediction and forecasting of the future
development of societies.
THE INFLUENCE OF CLASSICAL MUSIC ON THE GROWTH OF SOME VARIETIES OF CUCUMBERS AND TOMATOES GROWN IN GREENHOUSES
Authors: Khachatryan A. , Hakobyan J.
Published: January 2024

Greenhouse farms in Armenia are developing intensively from year to
year. The growth and development of plants grown in greenhouses is mainly
stimulated by chemicals, however, they can be partially replaced by the
influence of music. Scientists have proven the beneficial effect of music on the
growth of higher plants back in the last century.
We conducted experiments on local plant varieties purchased at the
“Scientific Center for Vegetables, Melons and Industrial Crops” in the village
of Darakert. During the day, with breaks, music was turned on for 6.5 hours.
The influence of classical music on various phases of growth and development
of greenhouse plants of local varieties of cucumbers “Hayarpi”, “Nare” and
tomatoes “Rubina”, “Ranni-Nush” was tested. Comparisons are provided with
plants of the same varieties grown without music.
As a result of the research, it was revealed that classical music, in which
sound waves oscillate in the range of 6 kHz, has a stimulating effect on the
growth of the studied varieties of cucumbers and tomatoes and their growth
exceeds the growth of plants grown without the influence of music.
SOFTWARE DEVELOPMENT PROJECT MANAGEMENT: PROJECT RISK MANAGEMENT
Authors: Алин Г.Т. , Рахимжанова Н.К.
Published: January 2024

в данной статье рассматриваются общие характеристики и основные технологии управления рисками в проектах разработки программных продуктов: определение рисков, ранжирование рисков по приоритету и выработка мер, связанных с компенсацией воздействия рисков на проект. Определены существующие подходы к управлению рисками проекта программной разработки, роли и задачи менеджера проекта и его команды в контексте управления рисками. В статье рассматривается необходимость анализа и учета рисков проекта, а также выделение необходимых временных и людских ресурсов для обеспечения конечного успеха в реализации проектов разработки программного обеспечения.
DIGITAL EDUCATIONAL RESOURCE “AUYL-SCHOOL.KZ”
Authors: Оналбаева А.Т. , Берлинова А.
Published: January 2024

Применение цифрового контента, интернет ресурсов в образовании в последнее время становится актуальным. Анализ литературы показал, что использование цифрового контента в образовании позволяет персонализировать учебное пространство для углубления знаний, привитию навыков критического мышления. Цифровая трансформация образования обусловлена современной реальностью и переходом системы образования в онлайн обучение. В период онлайн обучения возрастает необходимость создания ЦОР ― цифровых образовательных ресурсов, которые содержат видео- и аудио-, текстовой материал. Целью данного исследования является выявление наиболее эффективных способов проектирования, разработки и составления заданий по видам речевой деятельности для ЦОР по русскому языку и литературе в общеобразовательных школах. В статье обобщаются точки зрения исследователей по данной проблеме, в частности, проводится краткий обзор научной литературы, описываются задания по видам речевой деятельности для ЦОР: письмо, говорение, аудирование, чтение. Предлагаются интересные формы проектирования интерактивных заданий по русскому языку и литературе. Ценность проведенного исследования состоит в том, что полученные результаты можно применять в практике преподавания русского языка и литературы в общеобразовательных школах.
Quality of Life of Lower Limb Amputees; A Comparative Study between Rehabilitated vs Non-Rehabilitated Groups
Authors: Naz Somiya , Haider Syeda Sakina , Sarfraz Maham , Ghazanfar Iqra
Published: January 2024

Amputation is a surgical operation for the removal of a limb that is necessary when limb recovery is impossible, where lower limb amputation (LLA) is frequently carried out for several reasons, such as diabetes, infection, RTA, or locally unresectable tumors. Objective: To compare the quality of life of lower limb amputee population between rehabilitated and non-rehabilitated groups. Methods: A cross-sectional study was conducted on 185 patients having lower limb amputation, out of which 115 patients were taking physiotherapy sessions and 70 were not taking any physiotherapy sessions. The data were collected from CHAL Foundation Islamabad and CHAL Foundation Swabi. A self-structured questionnaire (containing demographics, and clinical characteristics of participants) and SF-36 questionnaire was used to gauge the quality of life of both rehabilitated and non-rehabilitated groups of lower limb amputees. Results: The findings indicate that there was a significant difference found in the quality of life of lower limb amputees between the rehabilitated group and the non-rehabilitated group. Conclusions: To conclude, in light of our preliminary findings, we infer that the quality of life of lower limb amputees in rehabilitated group participants was better than those of non-rehabilitated group participants.
Comparative Efficacy of Diode Laser System versus Intense Pulse Light (Ipl) In Management of Unwanted Hair
Authors: Ilyas Sara , Hussain Majid , Siddiqui Muhammad Adeel , Muzaffar Bushra , Gul Kiran , Sajjad Daniyal
Published: January 2024

Unwanted hair growth can be caused by several factors, including genetics, systemic illness, and even drug reactions. According to the underlying medical condition, excessive hair growth was labelled as either hirsutism or hypertrichosis. Objective: To compare the efficacy of diode laser system versus intense pulse light in the management of unwanted hair among female patients. Methods: Patients in this randomized controlled study had hirsutism. Group A received powerful pulse light therapy for three sessions, one month apart, while Group B received diode laser treatment. To determine the effectiveness and side effects in both groups, patients were monitored for four months and subsequently assessed clinically.  Results: Out of these total 60 patients, intense pulse light system was more efficacious in achieving patient satisfaction (73.3%) at the end of three months as compared to diode laser (26.7%) (p value < 0.001). Conclusions: This randomized controlled trial showed that intense pulse light therapy was more efficacious in management of unwanted hair compared to diode laser therapy.
Severe and Frequent Loneliness Mars Adults with Hearing Loss
Authors: Irum Aqsa , Mumtaz Nazia , Saqulain Ghulam , Asghar Amna , Dawood Tayyaba
Published: January 2024

There is a high prevalence of hearing loss in community and need of research to address this gap into the health-related issues of hearing loss like loneliness, anxiety and depression, hence current study was conducted. Objective: To determine the subjective loneliness in adults with hearing loss and association with clinico-demographic variables. Methods: This cross-sectional study was conducted at Isra University Islamabad, recruited N=377 patients with hearing loss utilizing convenience sampling from Sir Ganga Ram and Mayo Hospitals, Lahore, Pakistan from January 2020 to June 2020. The sample included both genders, aged 20 to 65 years with moderate to profound hearing loss of at least 1-year duration. The basic demographic sheet and University of California, Los Angeles (UCLA) Loneliness Scale Version 3 were used for data collection. Data were analyzed using SPSS Version 26 & Chi-square was utilized for association with p<0.05 taken to be significant. Results: Study revealed severe loneliness in 279(74%) and frequent loneliness in 98(26%). Severity categories of loneliness revealed association with age (p=0.049), gender (p=0.043), smoking (p=0.049), type of hearing loss (p<0.001), degree of hearing loss (p=0.008), hearing aid use (p<0.001), hours and days of hearing aid use (p<0.001). Conclusions: It is concluded that hearing loss results in severe and frequent loneliness. Factors including age, gender, smoking, type of hearing loss, degree of hearing loss, hearing aid use, hours and days of hearing aid use are associated with loneliness in adult population of Punjab, Pakistan.