bluuebunny/crossref_metadata_2025 huggingface dataset:
ФІНАНСОВА ЛОГІСТИКА ЯК КЛЮЧОВИЙ ЕЛЕМЕНТ СТІЙКОГО РОЗВИТКУ БІЗНЕСУ
Authors: Повод Т. М.
Published: February 2025

Стаття присвячена актуальним аспектам управлінських трансформацій у бізнесі, які визначаються стратегічною орієнтацією на адаптацію до швидких змін ринкового середовища. Основну увагу зосереджено на розвитку сучасної системи управління, яка включає впровадження технологій прозорості фінансових операцій, використання великих даних для оцінки ризиків і прогнозування, інтеграцію екологічних стандартів та створення адаптивних управлінських моделей. Важливу роль відіграє логістичний підхід до управління фінансовими потоками, що поєднує системний аналіз із інноваційними технологіями для оптимізації процесів управління. У статті розглянуто принципи, методи та особливості логістичного управління, які забезпечують ефективність фінансових потоків через гармонізацію внутрішніх і зовнішніх процесів. Аналізується недооцінка фінансової логістики в українських дослідженнях та підкреслюється її значення для досягнення довгострокової фінансової стабільності та конкурентоспроможності бізнесу. Відзначається необхідність інтеграції логістичного підходу з сучасними цифровими технологіями, такими як ERP-системи та великі дані, для підвищення прозорості й ефективності управлінських рішень. Підкреслено основне завдання фінансової логістики як ефективне управління фінансовими потоками з метою максимізації вартості бізнесу, з використанням фінансового прогнозування, планування, бюджетування та аналізу діяльності, високоефективних фінансових інструментів, орієнтованих на забезпечення максимального прибутку від операцій на фінансових ринках, управління ліквідністю та платоспроможністю, управління процесами фінансового лізингу, формування фінансових ресурсів і розробка інвестиційних програм. Запропоновано перспективи подальших досліджень, включаючи розробку адаптивних моделей управління фінансовими потоками, оцінку ефективності фінансової логістики та впровадження екологічних стандартів у фінансовий менеджмент. Стаття підтверджує значущість логістичного підходу як інструмента, що сприяє досягненню стратегічних цілей бізнесу, його адаптації та сталого розвитку в умовах глобалізації.
IMPLEMENTATION OF THE INDEPENDENT CURRICULUM IN LEARNING ISLAMIC RELIGIOUS EDUCATION AT THE DRIVING SCHOOL IN SDN SUB-DISTRICT BINAMU DISTRICT JENEPONTO
Authors: Rahman Syahrir , Rusli Rusli , Palangkey Rahmi Dewanty
Published: February 2025

The purpose of this study is to describe the teaching modules that have been compiled by Islamic Religious Education teachers. by Islamic Religious Education teachers under the Merdeka Curriculum at Mover School in SDN Binamu District, Jeneponto Regency. To describe the learning process carried out by Islamic Religious Education teachers by the Merdeka Curriculum at the Movers School in SDN Binamu District, Jeneponto Regency. SDN Binamu District, Jeneponto Regency. To describe the assessment of learning carried out by the Islamic Religious Education teacher following the Independent Curriculum at the Movers School in SDN Binamu Subdistrict, Jeneponto Regency. Jeneponto Regency. This study aims to identify the Merdeka Curriculum implemented in Islamic Religious Education learning at the Movers School, and to evaluate the effectiveness of implementing the Merdeka Curriculum in improving the quality of Islamic Religious Education learning, as well as its impact on student learning outcomes, to find out the factors that support and hinder the implementation of the Merdeka Curriculum in the context of Islamic Religious Education learning in these schools, as well as to provide recommendations to schools, educators, and other related parties regarding steps that can be taken to improve the implementation of the Merdeka Curriculum.
La asociación en participación
Authors:   Universidad de Guadalajara/Jalisco/México, Salcedo González Alejandro , Aviña Vázquez Carlos Rafael ,   Universidad de Guadalajara/Jalisco/México, Cantero Villalvazo Roberto ,   Universidad de Guadalajara/Jalisco/México
Published: February 2025

La asociación en participación data desde la antigüedad en donde figuras jurídicas como la commenda de los romanos se constituía para que una de las partes participara aportando capital y la otra participara con el trabajo de la travesía en el viaje, y ambas partes compartían las utilidades del negocio. En México, la asociación en participación se regula en 1934 en la Ley de Sociedades Mercantiles como un contrato y no como sociedad. Las características de la asociación en participación comparten las de un contrato bilateral y oneroso. Los efectos fiscales y laborales también se analizan en el presente ensayo.
El presupuesto maestro: sus fases de integración
Authors:   Universidad de Guadalajara/Jalisco/México, Aviña Vázquez Carlos Rafael , Medina Mares Eduardo ,   Universidad de Guadalajara/Jalisco/México, Mercado Maraveles Leticia ,   Universidad de Guadalajara/Jalisco/México
Published: February 2025

La evolución de la empresa moderna y de su forma funcional ha creado la necesidad de planear y controlar sus actividades con el objetivo de mejorar su desempeño económico. El presupuesto maestro es una herramienta efectiva para ayudar a la administración al logro de los objetivos de la corporación. Su origen se remonta a finales del siglo xvii, cuando se presentaban al parlamento británico los planes de gastos del reino y se daban pautas sobre su posible ejecución y control. Diferentes temas sobre el proceso presupuestal y la presupuestario han sido investigados por académicos. Nosotros, señalamos que la manera efectiva de que la empresa moderna logre sus objetivos es por medio de la presupuestación de las actividades de la empresa. El propósito de este artículo es analizar la integración de las diferentes fases del presupuesto maestro y de su relevancia para la planeación y control de las áreas funcionales de la corporación.
La reforma energética en México y la NIIF-6 para la industria petrolera y del gas
Authors:   Universidad de Guadalajara/Jalisco/México, Armenta Catalán Alfredo , Aviña Vázquez Carlos Rafael ,   Universidad de Guadalajara/Jalisco/México, Salcedo González Alejandro ,   Universidad de Guadalajara/Jalisco/México
Published: February 2025

La reforma energética se inició en el 2013 y se concreta en el 2014, terminando con el monopolio de la paraestatal Pemex en el uso exclusivo de los derechos de explotación de los hidrocarburos. La reforma energética se espera atraerá inversionistas nacionales y extranjeros. Existe la necesidad de que en nuestro país se fortalezcan la reglamentación y aplicación de las normas de información financiera, así como del impacto ambiental de las empresas de tal sector. El propósito de este artículo es analizar las principales características de la NIIF-6 para la etapa de extracción y evaluación de las industrias del petróleo y del gas.
Análisis de las debilidades fiscales de los municipios de México
Authors:   Universidad de Guadalajara/Jalisco/México, Sánchez Sierra Antonio , Daza Mercado Marco Antonio ,   Universidad de Guadalajara/Jalisco/México
Published: February 2025

México se encuentra entre los países que menor recaudación
obtiene en comparación con los países miembros de
la Organización para la Cooperación y Desarrollo Económico
(ocde). La concentración de la renta se ha producido
en unas cuantas regiones del país; solo en seis entidades
federativas. Los fondos federales incrementan la desigualdad
entre las entidades federativas, crean una dependencia
ocasionando a su vez una concentración de centralismo
económico y político. En México, el diseño institucional en
las reformas al artículo 115 constitucional aumenta las obligaciones locales, pero no las reglas o los incentivos para
enfrentar los desafíos y el incremento de ingresos fiscales
propios. El federalismo fiscal plantea un equilibrio entre la
centralización y la descentralización en los niveles de gobierno; por lo que plantea una distribución de la renta equitativa y eficiente en la asignación de recursos. Es necesario realizar modificaciones a los actuales esquemas de federalismo fiscal y proponer soluciones que puedan aplicar los diversos municipios de todo el país para que éstos puedan captar los recursos fiscales y que éstos puedan ser distribuidos en cada municipio que forma parte de México.
Eficacia en las sanciones a servidores públicos
Authors:   Universidad de Guadalajara/Jalisco/México, Álvarez Ascencio Esmeralda , Plascencia de la Torre Gloria María ,   Universidad de Guadalajara/Jalisco/México
Published: February 2025

La reforma constitucional y las leyes generales están cambiando el rumbo en la historia de México en materia de
corrupción y en el sistema de responsabilidades de los servidores públicos. Se infiere que los derechos humanos han impulsado estas reformas en el país, pues los mexicanos
tienen derecho a la igualdad, la legalidad, a tener una mejor
calidad de vida y oportunidades de empleo, no solo de manera privada, sino al servicio del Estado, a ser informados y a la rendición de cuentas por parte de los gobiernos. En el presente documento se analizarán la eficacia de estos cambios constitucionales en relación a la aplicación de sanciones a los servidores públicos. Es menester comentar que parte de esa eficacia ya se expresa en la exposición de motivos de la Ley General de Responsabilidades Administrativas y en los diarios de debates; sin embargo, se considera importante para este análisis, como parte complementaria de un sistema eficaz, el papel del tribunal sancionador, la interpretación de la norma de quién esté facultado para imponer las sanciones y, finalmente, más allá de la eficacia, analizar si estos cambios constitucionales reducirán la impunidad en México, la cual es considerada el origen de este mal.
The Role of Physicality in Professional Hockey: Examining the Impact of Fighting and Hitting on Gameplay, Team Dynamics, and Success
Authors:   , Vogel-Seidenberg Sammy
Published: February 2025

The purpose of this study was to investigate the role of physical play, more specifically fighting and hitting, in professional hockey, exploring the impact on gameplay, team dynamics, and success. Despite the significant rule changes within the National Hockey League (NHL) which focused on minimizing fighting, the strategic use of fighting and hitting remains a highly debated aspect of the sport. The study applies a basic qualitative research approach, gathering data through interviews, questionnaires, and game observations with current and former NHL, AHL, ECHL, players, coaches, referees, and analysts. Findings indicate that physical play, particularly hitting and fighting can positively impact game momentum, psychological play, and intimidate opponents as well at times help teams win games. Excessive reliance on fighting and hitting does not correlate with long-term success, but if used strategically, it can contribute to success over time. This study contributes to the ongoing discussion on player safety, changing strategies in team dynamics, and potential future policy directions for the NHL to balance tradition with modern gameplay demands.
Comprehensive Review of Carbon Capture Technologies for Climate Change Mitigation
Authors: Meylani Vita , Busaeri Nundang , Radjasa Ocky Karna , Hiron Nurul , Mutiara Frista
Published: February 2025

The emissions of carbon dioxide (CO2) significantly contribute to the rise in global temperatures and the exacerbation of climate change. Various initiatives have been undertaken to reduce CO2 emissions, notably through the adoption of carbon capture technologies. These technologies include Carbon Capture and Utilization (CCU), Carbon Capture and Storage (CCS), and the integrated approach of Carbon Capture, Utilization, and Storage (CCUS). Our study aims to elucidate the operational principles of CCU, highlight the benefits of carbon capture, and provide recent updates on the application of CCU and CCS in daily contexts. Utilizing a qualitative descriptive methodology through a literature review, we examine the primary sources related to CCU and CCS from various databases such as Scopus, Springer, Taylor & Francis, and Google Scholar, covering the period from 2014 to 2024. As a novelty, our review covers physical techniques like absorption, gas or membrane separation, and pressure-temperature manipulation, alongside chemical methods such as the adsorption of amine compounds. Furthermore, biological techniques, including fixation, are also utilized. The operational framework of carbon capture technology is structured around three main processes: pre-combustion, post-combustion, and oxy-combustion. Notably, carbon capture technology incorporates the cultivation of microalgae as a fixation strategy, which promotes not only environmental sustainability but also shows significant promise for future applications. This method effectively sequesters large quantities of CO2 while requiring minimal nutritional resources. The advantages of utilizing microalgae include enhanced efficiency in CO2 fixation compared to terrestrial plants, reduced contamination, and a relatively simple operational structure. It is evident that the adoption of carbon capture technology is expected to increase in the coming years, particularly in light of the ongoing challenges posed by climate change. Prospective advancements in carbon capture technology are then discussed based on the review result. Thus, our literature review contributes to promoting the broader implementation of carbon capture technologies.
Harnessing Carbon Trading and Life Cycle Assessments for Renewable Energy Transition in Southeast Asia
Authors: Hendriarto Stevanus , Manap Yusril Sudiro Abdul , Runtukahu Yussuf Eddo , Utomo Romualdus Nugraha Catur
Published: February 2025

The climate crisis, caused by fossil fuel dependence and deforestation, poses significant socio-economic and environmental challenges for Southeast Asia, including reduced agricultural productivity and increased health risks. Our study aims to fill this gap by assessing how renewable energy can mitigate these impacts, focusing on the region's potential and the mechanisms needed to support this energy transition. Through a structured review of peer-reviewed articles, government reports, and data from intergovernmental organizations, we analyzed Southeast Asia's renewable energy potential and the roles of carbon trading and life cycle assessments (LCA) as enabling mechanisms. Our findings reveal that, despite projected increases in CO₂ emissions from 1.4 gigatons (Gt) in 2018 to nearly 2.4 Gt by 2040, Southeast Asia has set ambitious targets to reduce energy consumption by 23% and increase renewable energy to 22.1% within the same timeframe. Achieving these goals will require robust, adaptive policies that incentivize renewable investment and promote regional cooperation. Carbon trading and LCA are identified as pivotal tools, providing financial motivation for emission reductions and offering frameworks to assess the environmental impacts of energy projects. In conclusion, this study suggests that Southeast Asia’s renewable energy adoption, supported by sustainable practices like carbon trading and LCA, could significantly advance both global climate mitigation and socio-economic resilience within the region.
Terapi Foot Massage untuk Menurunkan dan Menstabilkan Tekanan Darah pada Penderita Hipertensi Gestasional
Authors: Herdiana Yana , Galaupa Resi , SR Nurqalbi
Published: February 2025

Hipertensi atau tekanan darah tinggi merupakan suatu kondisi dengan tekanan darah yang meningkat secara terus menerus pada pembuluh darah. Hipertensi di definisikan sebagai tekanan darah sistolik kurang lebih 140 mmHg serta tekanan darah diastolik kurang lebih 90 mmHg. pijat kaki merupakan alternatif terbaik untuk mengurangi tingkat tekanan darah diantara penderita hipertensi. Pijat memiliki efek meningkatkan sirkulasi, mengeluarkan produk sisa dari tubuh, meningkatkan mobilitas sendi, mengurangi rasa sakit dan menguragi ketegangan otot. Tujuan penelitian ini untuk Mengetahui terapi foot massage untuk menurunkan dan menstabilkan tekanan darah pada penderita hipertensi gestasional di Puskesmas Saketi Tahun 2023. Metode yang digunakan yaitu penelitian quasi experimental dengan pendekatan one group pre post design. Penelitian ini memberikan pretest kepada responden sebelum dilakukan foot massage dan post test sesudah melakukan foot massage. Analisis data menggunakan Wicoxon Signed Rank Test. Populasi dalam penelitian ini adalah ibu hamil penderita hipertensi yaitu 30 orang. Hasil penelitian menunjukkan terdapat pengaruh Terapi Foot Massage untuk menurunkan dan  menstabilkan tekanan darah (nilai p = 0,000) pada penderita hipertensi gestasional di Puskesmas Saketi Tahun 2023.
Evaluasi Pengelolaan Limbah Bahan Berbahaya Beracun (B3) di Puskesmas Wilayah Kabupaten Batanghari Provinsi Jambi
Authors: Marni Marni , Hardiana Hedy , Romli M.
Published: February 2025

Limbah medis dan nonmedis di Puskesmas Kabupaten Batanghari, jika tidak dikelola dengan baik, dapat berdampak negatif pada kesehatan dan lingkungan. Penelitian ini bertujuan mengevaluasi sistem pengelolaan limbah medis di Puskesmas di 5 puskesmas di Kabupaten Batanghari yang sesuai dengan PERMEN LHK NO 56 Tahun 2015. Jenis penelitian yang digunakan adalah penelitian kualitatif dengan menggunakan pendekatan studi kasus. Hasil penelitian secara umum, pengelolaan limbah medis di puskesmas menunjukkan variasi dalam kesiapan teknis, regulasi, dan sumber daya. Proses pengelolaan limbah berjalan baik, tetapi perbaruan peralatan seperti cold storage masih diperlukan. Output mencakup limbah yang diolah sesuai standar, untuk peningkatan kesadaran staf, dan dokumentasi cukup memadai, dengan dampak positif pada keamanan pasien, kesehatan masyarakat, dan lingkungan. Rekomendasi termasuk standardisasi infrastruktur dengan mempertimbangkan pengadaan cold storage, pelatihan berkala, kolaborasi antar Puskesmas, peran aktif Dinas Kesehatan, evaluasi layanan pihak ketiga, adopsi teknologi digital, dan siklus pemantauan berkelanjutan. Rekomendasi ini diharapkan dapat meningkatkan efisiensi, memastikan kepatuhan regulasi, dan melindungi lingkungan di Puskesmas Kabupaten Batanghari.
Analisis Pengelolaan Limbah Medis Puskesmas di Kota Banda Aceh
Authors: Sufiani Dessi , Ramadhani Nur Rizky , Lukman Lukman
Published: February 2025

Pusat kesehatan masyarakat (Puskesmas) menghasilkan volume limbah medis Bahan Berbahaya Beracun (B3) yang besar dan merata diseluruh Indonesia. Menurut data dari Kemenkes RI tahun 2020 Puskesmas yang melakukan pengelolaan limbah medis sesuai dengan standar. Penelitian ini bertujuan untuk menganalisis pengelolaan limbah medis puskesmas di Kota Banda Aceh. Penelitian ini menggunakan metode penelitian kualitatif dengan rancangan studi kasus serta pengumpulan data dengan teknik wawancara, observasi dan telaah dokumen. Informan kunci dalam penelitian ini berjumlah 17 orang yaitu Kepala Bidang Kesehatan Masyarakat Dinas Kesehatan Kota Banda Aceh (1 orang), Kepala Seksi Penyehatan Lingkungan (1 orang), Kepala puskesmas (5 orang), informan pendukung  tenaga sanitarian (5 Orang), dan tenaga pelaksana pengelola limbah medis di puskesmas (5 orang). yang ditentukan melalui tekhnik purpose sampling.  temuan emperis diketahui bahwa puskesmas diKota Banda Aceh telah melakukan pengelolaan sampah limbah padat mulai dari pemilahan, pengumpulan, penyimpanan dan pengangkutan, dalam pengelolaan limbah medis cair sudah menggunakan IPAL (Instalasi pengelolaan Air Limbah) yang disalurkan melalui wastafel khusus pada tiap ruangan, masih tidak sesuai dengan Peraturan Menteri Lingkungan Hidup RI No. 68 Tahun 2016 karena membuang limbah medis cair langsung sedangkan pada limbah padat medis pada tahap pengelolaan dan pemusnahan masih tidak sesuai dengan Permenkes RI Nomor 18 Tahun 2020 yaitu penyimpanan sementara lebih dari 2 hari namun tidak menggunakan cold storage. Kesimpulan : Dinas Kesehatan diharapkan dapat merencanakan pengadaan Cold Storage, Rehabilitasi tempat penyimpanan sementara, rehabilitasi saluran IPAL dan peningkatan SDM pelaksana ( cleaning service) dengan OJT (on the job training ) yang disertai dengan sertifikat pelatihan.
Thought Leadership on the Revolutionary Developments in Organizations
Authors: Brady Ursula , Kuria Kathy , Bell Reginald L.
Published: February 2025

This study investigated thought leadership concerning organizational growth strategies. Internal Thought Leaders (ITL) and External Thought Leaders (ETL) we identified in the literature to be directly related to achieving revolutionary developments in organizations (RDO). We found that ITL are better suited for setting goals, aligning resources, and fostering innovations; on the other hand, ETL were better suited to advance organizational reputation. We explicate a progressive thought leadership framework that works best to sustain organizational growth strategies. This integrative approach can impact ethical decision-making, leadership styles, operation efficiencies and return on investments if done properly. Because thought leadership influences a collective mindset among workers, we were able to make several recommendations for managers seeking to influence their organizational growth strategies.
Giardia intraflagellar transport protein 88 is involved in flagella formation
Authors: Yeo Hye Rim , Shin Mee Young , Kim Juri , Park Soon-Jung
Published: February 2025

Intraflagellar transport (IFT) particles, a multi-protein apparatus composed of complex A and B, are known to be involved in homeostasis of flagella formation. IFT particles have recently become an interesting topic in Giardia lamblia, which has 4 pairs of flagella. In this experiment, we examined the function of giardial IFT components. When 7 components (IFT121, 140, 20, 46, 52, 81, and 88) of IFT were expressed in Giardia trophozoites as a tagged form with mNeonGreen, all of them were found in both flagella pores and cytoplasmic axonemes. In addition, motor proteins for IFT particles (kinesin-13 and kinesin-2b), were localized to a median body and cytoplasmic flagella, respectively. The CRISPRi-mediated knockdown of IFT88 significantly affected the lengths of all 4 flagella compared to the control cells, Giardia expressing dead Cas9 using control guide RNA. Decreased expression of kinesin-2b also resulted in shortening of flagella, excluding the ventral flagella. Live Giardia cells expressing IFT88-mNeonGreen clearly demonstrated fluorescence in flagella pores and cytoplasmic axonemes. These results on IFT88 and kinesin-2b indicate that IFT complex plays a role in maintenance of G. lamblia flagella.
Anti-tumor effects of Toxoplasma gondii and antigen-pulsed dendritic cells in mice bearing breast cancer
Authors: Kim Bong Kyun , Choi Hei Gwon , Lee Jae-Hyung , Choi In Wook , Yuk Jae-Min , Cha Guang-Ho , Lee Young-Ha
Published: February 2025

Cancer immunotherapy is widely used to treat various cancers to augment the weakened host immune response against tumors. Dendritic cells (DCs) are specialized antigen-presenting cells that play dual roles in inducing innate and adaptive immunity. Toxoplasma gondii is a protozoan parasite that exhibits anti-tumor activity against certain types of cancers. However, little is known about the anti-tumor effects of T. gondii or tumor/parasite antigen-pulsed DCs (DC vaccines, DCV) in breast cancer. In this study, C57BL/6 mice were administered E0771 mouse breast cancer cells (Cancer-injected) subcutaneously, T. gondii Me49 cysts orally (TG-injected), or DCs pulsed with breast cancer cell lysate antigen and T. gondii lysate antigens (DCV-injected) intraperitoneally. Tumor size and immunological characteristics were subsequently evaluated. We also evaluated matrix metalloproteinase (MMP)-2 and MMP-9 levels in E0771 mouse breast cancer cells co-cultured with T. gondii or DCs by RT-PCR. The tumor volumes of mice injected with breast cancer cells and antigen-pulsed DCs (Cancer/DCV-injected mice) were similar to those of Cancer-injected mice; however, they were significantly reduced in T. gondii-infected tumor-bearing (TG/Cancer-injected) mice. Moreover, tumor volumes were significantly reduced by adding antigen-pulsed DCs (TG/Cancer/DCV-injected mice) compared to TG/Cancer-injected mice. The levels of IFN-γ, serum IgG2a levels, and CD8+ T cell populations were significantly higher in DCV- and TG-injected mice than in control mice, while no significant differences between Cancer- and Cancer/DCV-injected mice were observed. The levels of IFN-γ, the IgG2a levels, and the percentage of CD8+ T cells were significantly increased in TG/Cancer- and TG/Cancer/DCV-injected mice than in Cancer-injected mice. IFN-γ levels and serum IgG2a levels were further increased in TG/Cancer/DCV-injected mice than in TG/Cancer-injected mice. The MMP-2 and MMP-9 mRNA expressions were significantly decreased in mouse breast cancer cells co-cultured with live T. gondii, T. gondii lysate antigen, or antigen-pulsed DCs (DCV) but not in inactivated DCs. These results indicate that T. gondii induces anti-tumor effects in breast cancer-bearing mice through the induction of strong Th1 immune responses, but not in antigen-pulsed DCs alone. The addition of antigen-pulsed DCs further augments the anti-tumor effects of T. gondii.
Anxiolytic Effects of Nutritional Strategies in Craniofacial Inflammatory Conditions: A Scoping Review
Authors: Yusuf Hajrah , Mukhtar Nur Anam
Published: February 2025

Introduction: Craniofacial inflammatory conditions, such as temporomandibular joint disorders and periodontitis, are often linked to heightened anxiety-like responses. Emerging evidence suggests that nutritional strategies may serve as effective, non-pharmacological approaches to mitigate anxiety under such conditions. Objective: To systematically review the evidence on the anxiolytic effects of dietary strategies, such as omega-3 fatty acids, magnesium, probiotics, and curcumin, in individuals or animal models experiencing craniofacial inflammatory conditions. Methods: PubMed, Scopus, and Web of Science were systematically searched for studies published up to January 2025. Studies were included if they evaluated the impact of nutritional interventions on anxiety outcomes in populations with craniofacial inflammation. Relevant data on the study population, interventions, and outcomes were extracted and summarized. Review/Discussion: Five studies were included, comprising human and animal research. Omega-3 fatty acids and magnesium supplementation were associated with reduced anxiety scores and inflammatory markers. Probiotics showed improvement in psychological symptoms and systemic inflammation. Curcumin demonstrated anxiolytic effects by reducing oxidative stress, with combined omega-3 and curcumin showing synergistic benefits. Despite promising results, significant variability in methodologies and outcome measures limits the generalizability of findings. Conclusion: Nutritional strategies hold promise for reducing anxiety in craniofacial inflammatory conditions. Further research with standardized protocols is needed to validate these findings and inform clinical applications.
Mewujudkan Relasi Suami Istri Yang Berkeadilan Gender : Kritik Forum Kajian Kitab Kuning Terhadap 'Uqud Al-Lujjayn
Authors: Siti Nurkholisoh
Published: February 2025

Kesetaraan gender dalam pernikahan adalah elemen penting dalam menciptakan hubungan harmonis dan berkeadilan. Penelitian ini mengeksplorasi konsep keadilan gender dalam konteks hubungan suami istri berdasarkan kitab 'Uqud al-Lujjayn karya Syekh Nawawi al-Bantani dan kritik yang diajukan oleh Forum Kajian Kitab Kuning (FK3). Tujuan penelitian ini adalah untuk menganalisis norma-norma gender dalam teks tersebut yang dikritik oleh Kajian Kitab Kuning mengenai pembaruan pandangan tentang peran gender. Metode yang digunakan adalah analisis konten melalui studi pustaka, dengan pendekatan kualitatif-deskriptif untuk mengeksplorasi argumen-argumen dari kedua sumber. Hasil penelitian menunjukkan bahwa meskipun 'Uqud al-Lujjayn memberikan panduan berharga tentang hak dan kewajiban suami-istri, beberapa isi kitab cenderung membatasi peran perempuan. FK3 menyoroti perlunya reinterpretasi ajaran-ajaran klasik untuk mencapai kesetaraan gender yang lebih baik. Dengan memperkuat kesadaran akan hak-hak gender dan dialog terbuka, diharapkan tercipta lingkungan yang inklusif dan adil dalam masyarakat. Penelitian ini menegaskan bahwa pemahaman gender dalam Islam harus melampaui pembagian tugas dan menghargai kesetaraan, demi menciptakan keluarga yang aman dan sejahtera bagi semua individu
Linguistic and Mathematical Approaches to Deep Neural Networks Training and Artificial Intelligence: The Confluence of Paths for AI Development
Authors: Zuanelli Elisabetta
Published: February 2025

AI can be briefly defined as the emulation of the functions/activities of human brain/mind by the machine. This statement has generated the basic assumptions for the development of algorithms in AI and specifically, among others, for deep neural networks training. However, a semantic flaw lies in the definition of AI in terms of neural networks and specifically in the distinction between brain and mind. In fact, brain is the neuro-physiological support of mind. Therefore, in order to investigate human functions we must refer to the notion of mind. The notion of mind in cognitive psychology and cognitive linguistics/semantics refers to the human faculty of knowledge acquisition, memorization and use of information for all kinds of human activities whether physical or intellectual. Signals conveyed to the mind utilize different channels/sensors, namely what we call human senses that input noises, sounds, images, chemical stimuli, etc. to the central semantic memory. In this activity the question is: how is the meaning of single specific different inputs analysed, interpreted, stored and related to other inputs by the human mind. A fantastic question: it’s what we call the meaning of meaning. A basic problem, then, concerns the meaning/value assigned to single elements/entities in mind and the meaning of their interrelation. This process is conferred to the splitting and definition of human experiences by means of mental representations translated into words. In linguistics, this faculty is what we call the semantic omnipotence of language and its metalinguistic capability tro represent conceptually and linguistically all human experiences and its reflexive capability to explain itself: words to explain words. The semantic omnipotence of human language is defined as the potential capability of the human mind to create and use indefinite systems of signs/languages, whether natural or artificial ones, such as the languages of mathemathics, physics or computer science, endowed with symbols, syntax, semantics, etc. Therefore the preliminary question on mathematics is: could mathematics exist without a preliminary conceptual linguistic representation of the physical/mathematical concepts to be coded? Now, let us turn to the specific application of mathematical concepts/ functions to the computer science.
Deep Learning Models For Classification of Covid-19 Severity Levels
Authors: Olabode Olatubosun , Akintola Kolawole Gabriel , Adeyemi Ebenezer , Akinyede Olufemi Rapheal , Afeni Babajide , Racheal Akinbo , Olabode Adekemi Iyabo , Akinrinwa Sadura Pricilla
Published: February 2025

In addition to clinical investigations, the RT-PCR testing is an alternative to the diagnosis of COVID-19 disease. This is considered the gold standard because it has the ability to find SARS-CoV-2 ribonucleic acid (RNA) that is located in the respiratory specimen. Radiologists interpret chest radiography (X-ray), to screen for COVID-19, by identifying visual indicators that is linked to SARS-CoV-2 viral infection. Radiologists also identify specific radiographic abnormalities in COVID-19-positive cases. Specifically, the ground-glass opacities, interstitial changes and bilateral abnormalities, in CT images and chest X-ray images are of interest in medical diagnosis. We propose a framework that combines clinical investigation, RT-PCR testing, and radiographic examination of (COVID-19) patients to accurately label chest X-ray images into the categories of mild, moderate, and severe. With chest X-ray images of patients with infection, we train a transfer learning VGG16 model and a developed convolution neural network (CNN) model to detect the presence of infection and classify it according to its severity level. This severity classification model can assist clinicians in prioritizing RT-PCR testing for COVID-19 confirmation and deciding on appropriate treatment strategies tailored to the infection's severity, given that different infection severities require varying treatment approaches. Our model was trained on datasets from public domains and local hospitals. We adopt Adam optimizer and a learning rate strategy that decreases if learning stagnates ('patience'). Hyperparameters for training include a learning rate of 2e−4, 20 epochs, a batch size 64, a decay factor of 0.7, and patience 5. Additionally, we implement a batch re-balancing strategy to ensure a more equitable distribution of infection types within each batch. We developed and evaluated our initial model prototype with the Keras deep learning and TensorFlow. The VGG16 network validation yielded impressive performance metrics, with specificity at 0.94, sensitivity at 0.91, and an F1-score of 0.92 for the COVID-19 severity classification. Similarly, the proposed CNN-based classification achieved high performance with specificity 0.91, sensitivity 0.91, and an F1-score of 0.91.
Sistem Booking Makeup Artist Berbasis Web Menggunakan Algoritma SHA-256
Authors: Cut Agusniar  , Muslimah Siregar Khanifa , Rasyid Rasmiati
Published: February 2025

Sistem Booking Makeup Artist (HaniBunny MUA) adalah sebuah sistem pemesanan jasa Makeup Artist (MUA) berbasis web yang dirancang untuk mempermudah pelanggan dalam mencari dan memesan jasa makeup artist untuk berbagai kebutuhan, seperti acara pernikahan, pesta dan photoshoot. Sistem ini dilengkapi dengan fitur utama yaitu registrasi dan login untuk pengguna dan admin, serta fitur pemesanan yang memungkinkan pengguna untuk memilih MUA sesuai dengan preferensi dan jadwal yang diinginkan. Pengimplementasian website ini menggunakan Bahasa Pemograman Python dengan teknologi Mikroframework Flask sebagai framework backend dan SQLite sebagai database untuk penyimpanan data pengguna dan pemesanan. Peningkatan keamanan data, algoritma Secure Hash Algorithm - 256 (SHA-256) digunakan untuk mengenkripsi kata sandi pengguna sebelum disimpan di database, memastikan perlindungan data dari akses tidak sah. Pengguna dapat melihat daftar makeup style yang tersedia beserta deskripsi layanan yang ditawarkan, serta mengakses halaman pemesanan untuk memilih tanggal, layanan yang akan dipilih, dan mengisi informasi kontak. Sebagai tambahan, admin dapat mengelola data booking dan pengguna melalui dashboard yang sudah disediakan. Sistem Booking Makeup Artist ini bertujuan untuk meningkatkan efisiensi dan kenyamanan dalam proses pemesanan jasa MUA, sekaligus memberikan platform yang mudah digunakan bagi semua kalangan. Dengan penggunaan sistem berbasis web, Sistem Booking Makeup Artist ini dapat diakses kapan saja dan di mana saja, memberikan kemudahan dalam merencanakan momen spesial dengan tampilan makeup yang sempurna.
Sistem Monitoring Irigasi dan Prediksi Debit Air Berbasis IoT Dan Support Vector Machine (SVM)
Authors: Cinderatama Toga Aldila , Zulmy Alhamri Rinanza , Yunhasnawa Yoppy , Sofian Efendi Fery , Ariyanto Rudy
Published: February 2025

Menurut data BPS yang dirilis pada Oktober 2023 mengenai data pertanian, jika dilihat dari luasan lahan pertanian, luas panen padi pada 2023 diperkirakan sekitar 10,20 juta hectare mengalami penurunan sebanyak 255,79 ribu hektare atau 2,45 persen dibandingkan luas panen padi di 2022 yang sebesar 10,45 juta hektare. Dengan penurunan luasan lahan panen padi tersebut perlu dipikirkan berbagai cara untuk lebih meningkatkan hasil pertanian dan mencegah terjadinya kesenjangan yang tinggi antara tingkat kebutuhan dan tingkat pemenuhan bahan makanan. Salah satu cara yang dapat dilakukan adalah mengoptimalkan lahan pertanian yang tersedia dengan panca usaha tani dan pengairan yang optimal, sehingga diperlukan jaringan irigasi beserta bangunan irigasi dalam keadaan baik. Penelitian ini memanfaatkan teknologi IoT untuk monitoring debit serta memprediksinya menggunakan metode Supervised learning-Support Vector Machine (SVM). Metode penelitian yang akan dilakukan meliputi : Analisis Kebutuhan, perancangan, implementasi, pengujian dan pemeliharaan. Hasil dari penelitian ini adalah telah berhasil Merancang dan membangun sistem monitoring debit air pada irigasi pertanian berbasis platform Internet of Things menggunakan sensor water flow, sensor ultrasonic HCSR04 dan sensor suhu ds18b20, dilengkapi dengan aplikasi monitoring berbasis android untuk memonitor dan mengambil data history debit air. Aplikasi prediksi debit air pada irigasi pertanian juga telah diimplementasikan menggunakan support vector machine terutama menggunakan linier regression dan diperoleh hasil prediksi debit air dengan kondisi saat pemantauan berada pada kisaran 1500 liter/menit atau 25 liter per detik.
Analisis Wacana Penerapan Internet Of Things di Lingkungan Kampus Dengan Metode Critical Discourse Analysis
Authors: Ahmad Fauzi  , Sulhan Moh
Published: February 2025

Penelitian ini menganalisis penerapan Internet of Things (IoT) di lingkungan kampus dengan menggunakan pendekatan Critical Discourse Analysis (CDA). Tujuan utama dari penelitian ini adalah untuk mengeksplorasi peluang, tantangan, dan implikasi potensial dari adopsi IoT dalam menciptakan kampus cerdas (smart campus). Dengan menganalisis kebijakan terkait IoT, wawancara dengan mahasiswa, dosen, dan staf kampus, serta observasi terhadap infrastruktur kampus, penelitian ini mengungkapkan tiga kategori utama: peluang, tantangan, dan implikasi potensial. Peluang yang ditemukan mencakup efisiensi operasional dalam pengelolaan ruang kelas dan laboratorium, peningkatan pengalaman belajar mahasiswa, dan kontribusi terhadap keberlanjutan lingkungan melalui sistem hemat energi berbasis IoT. Tantangan utama yang dihadapi adalah keterbatasan infrastruktur kampus, kekhawatiran mengenai privasi data, dan kendala anggaran. Sedangkan implikasi potensial mencakup kesenjangan akses teknologi bagi mahasiswa dari latar belakang ekonomi kurang mampu, serta kebutuhan akan kebijakan inklusif dan pelatihan staf untuk mendukung penerapan IoT secara efektif. Penelitian ini menyarankan langkah-langkah strategis untuk memperkuat infrastruktur jaringan, kebijakan perlindungan data, dan keterlibatan seluruh pemangku kepentingan dalam perencanaan dan implementasi IoT di kampus. Dengan demikian, penerapan IoT di kampus tidak hanya membutuhkan teknologi yang canggih, tetapi juga pendekatan yang holistik, inklusif, dan berorientasi pada kebutuhan semua pihak. Upaya kolaboratif antara manajemen kampus, mahasiswa, dosen, dan staf menjadi kunci dalam memastikan IoT dapat membawa manfaat maksimal sekaligus mengatasi tantangan yang ada. Temuan ini memberikan wawasan penting bagi institusi pendidikan tinggi dalam merancang kebijakan dan strategi adopsi IoT yang berkelanjutan dan inklusif.
Implementasi Data Mining Algoritma Apriori Pada Data Transaksi Pik Store
Authors: Achmad Arda Fahmi , Abdul Rahim  , Naufal Azmi Verdikha
Published: February 2025

Peningkatan laju pertumbuhan konsumen dirasa dapat dimanfaatkan oleh Pik Store untuk semakin berkembang dengan jajaran produk rekomendasi. Data dari bulan Maret hingga Juni 2023 menunjukkan banyak data transaksi yang diperoleh sebanyak 2016 data. Ruang lingkup penelitian ini adalah penerapan apriori dapat memberikan rekomendasi tata letak produk agar dapat diimplementasikan. Tujuan penelitian ini adalah mengidentifikasi pola pembelian konsumen dalam menemukan kombinasi item produk yang sering dibeli secara bersamaan menggunakan dengan metode asosiasi serta memberikan rekomendasi tata letak paket item produk berdasarkan pola pembelian yang diidentifikasi untuk meningkatkan penjualan di toko Pik Store. Metode penelitian melibatkan pengumpulan data dan penerapan algoritma Apriori untuk training dan validasi. Hasil dari penelitian ini adalah algoritma yang dapat merekomendasikan tata letak produk pada toko Pik Store. Tingkat confidence tertinggi yang didapat adalah 86% dengan rata – rata 61% dimana penulis mengatur nilai minimal support 7%. Penelitian selanjutnya diharapkan dapat mengembangkan model dengan tingkat confidence yang lebih tinggi dengan menerapkan metode yang lebih baik.
Biodegradable polyester-based hyperbranched nanocarrier-modified with N-acetyl glucosamine for efficient drug delivery to cancer cells through GLUTs
Authors: Shaikh Aazam , Salve Rajesh , Sengar Devyani , Gajbhiye Virendra
Published: February 2025

Cancer, ranking just below cardiovascular diseases, is a leading cause of mortality worldwide. The key to enhancing survival rates among cancer patients lies in the early detection, removal, and treatment of tumors. However, the broad-spectrum nature of current treatments, including chemotherapy and radiation therapy, results in significant collateral damage to healthy cells and tissues. In this context, hyperbranched polymers present a promising avenue for more targeted therapy. These polymers can be loaded with chemotherapeutic drugs and modified with specific ligands to selectively target cancer cells via glucose transporters, which are overexpressed in many cancer types. To enhance the delivery of drugs to cancer cells, we have engineered an N-acetyl glucosamine conjugated version of this polymer. The characterization of these nanocarriers was evaluated using various techniques, including 1H NMR, dynamic light scattering, and FTIR spectroscopy. Additionally, confocal microscopy was utilized to compare the accumulation of doxorubicin in cancer cells using both the N-acetyl glucosamine-conjugated and unmodified versions of H40 Boltorn™. Our observations indicated a superior accumulation of doxorubicin in cells treated with the modified H40 polymer. Further evaluation of the drug-loaded nanocarriers was conducted on MDA-MB-231 and 4T1 breast cancer cell lines, focusing on their cytotoxic effects. This suggests that the targeted delivery of anticancer drugs using the modified H40 Boltorn™ nanocarriers significantly enhances the ability to kill breast cancer cells, offering a more efficient and selective approach to chemotherapy that minimizes impact on healthy tissues and cells.
Decellularization techniques: unveiling the blueprint for tracheal tissue engineering
Authors: Gomes Keisha T. , Prasad Palla Ranga , Sandhu Jagnoor Singh , Kumar Ashwini , Kumar Naveena A. N. , Shridhar N. B. , Bisht Bharti , Paul Manash K.
Published: February 2025

Certain congenital or acquired diseases and defects such as tracheo-oesophageal fistula, tracheomalacia, tracheal stenosis, airway ischemia, infections, and tumours can cause damage to the trachea. Treatments available do not offer any permanent solutions. Moreover, long-segment defects in the trachea have no available surgical treatments. Tissue engineering has gained popularity in current regenerative medicine as a promising approach to bridge this gap. Among the various tissue engineering techniques, decellularization is a widely used approach that removes the cellular and nuclear contents from the tissue while preserving the native extracellular matrix components. The decellularized scaffolds exhibit significantly lower immunogenicity and retain the essential biomechanical and proangiogenic properties of native tissue, creating a foundation for trachea regeneration. The present review provides an overview of trachea decellularization advancements, exploring how recellularization approaches can be optimized by using various stem cells and tissue-specific cells to restore the scaffold’s structure and function. We examine critical factors such as mechanical properties, revascularization, and immunogenicity involved in the transplantation of tissue-engineered grafts.
Batch-fabricated full glassy carbon fibers for real-time tonic and phasic dopamine detection
Authors: Siwakoti Umisha , Pwint May Yoon , Broussard Austin M. , Rivera Daniel R. , Cui X. Tracy , Castagnola Elisa
Published: February 2025

Dopamine (DA) is a critical neurotransmitter that is key in regulating motor functions, motivation, and reward-related behavior. Measuring both tonic (baseline, steady-state) and phasic (rapid, burst-like) DA release is essential for elucidating the mechanisms underlying neurological disorders, such as schizophrenia and Parkinson’s disease, which are associated with dysregulated tonic and phasic DA signaling. Carbon fiber microelectrodes (CFEs) are considered the gold standard for measuring rapid neurotransmitter changes due to their small size (5–10 µm), biocompatibility, flexibility, and excellent electrochemical properties. However, achieving consistent results and large-scale production of CFE arrays through manual fabrication poses significant challenges. We previously developed flexible glassy carbon (GC) microelectrode arrays (MEAs) and GC fiber-like MEAs (GCF MEAs) for neurotransmitter detection and electrophysiology recording. We also demonstrated the feasibility of fabricating GC MEA with both GC electrodes and interconnects made from a single homogeneous material, eliminating the need for metal interconnections and addressing related concerns about electrical and mechanical stability under prolonged electrochemical cycling. Building on our prior experience, we now present a double-etching microfabrication technique for the batch production of 10 μm × 10 µm full GC fibers (fGCFs) and fGCF arrays, composed entirely of homogeneous GC material. This process uses a 2 µm-thick low-stress silicon nitride as the bottom insulator layer for the fGCFs. The effectiveness of the fabrication process was validated through scanning electron microscophy (SEM) and energy dispersive X-ray spectroscopy (EDS) elemental analyses, which confirmed the uniformity of the Si₃N₄ insulation layer and ensured the overall integrity of the fGCFs. Using finite element analysis, we optimized the fGCF form factor to achieve self-penetration up to 3 mm into the mouse striatum without additional support. The electrochemical characterization of fGCFs demonstrated high electrical conductivity and a wide electrochemical window. The ability of fGCFs to detect phasic and tonic DA release was confirmed using fast scan cyclic voltammetry (FSCV) and square wave voltammetry (SWV), respectively, both in vitro and in vivo. With their high sensitivity for phasic and tonic DA detection, combined with a scalable fabrication process and self-supporting insertion capability, fGCFs are promising sensors that offer enhanced practicality for comprehensive DA monitoring.