bluuebunny/crossref_metadata_2025 huggingface dataset:
Nutrición enteral domiciliaria prescrita en el Hospital Universitario Infanta Cristina de Badajoz (España)
Authors: Luengo Pérez Luis Miguel , Guerra Martínez Sara , Georgescu Laura Monica
Published: February 2017

Objetivo: Conocer la práctica real de la Nutrición Enteral Domiciliaria en la Unidad de Nutrición del Hospital Universitario Infanta Cristina de Badajoz durante 12 meses y, de forma secundaria, comparar los datos existentes con otros centros a nivel nacional e internacional.Método: Estudio descriptivo, observacional y retrospectivo de los pacientes atendidos por la Unidad de Nutrición, en el ámbito de la nutrición enteral domiciliaria, durante 12 meses consecutivos.Resultados: El número de pacientes mayores de 14 años con NED durante los 12 meses del estudio fue de 176 (52% varones). La edad media fue de 71,3 años (17- 104) y la duración media del soporte de 10 meses (307,16 días), con causa de finalización más frecuente el fallecimiento (78,2%). La enfermedad de base que se registró con más frecuencia fue la neurológica en 97 pacientes (55,1%), seguida de la neoplásica en 55 (31,3%). La vía de administración más utilizada fue la sonda nasogástrica (69,3%), seguida de la gastrostomía (14,2%) y la oral (10,8%). El 42,05% de los pacientes presentaban una actividad limitada y el 30,1% estaba confinado en cama/sillón. El 73,3% de los adultos requerían ayuda total o parcial. El suministro de la fórmula se hacía desde las farmacias de referencia, mientras que el material fungible se suministraba desde Atención Primaria en el 78,4% y desde el hospital en el resto.Conclusión: El número de pacientes registrados aumenta en relación con los años anteriores, pero se mantienen diferencias respecto a registros a nivel nacional e internacional.
La asistencia domiciliaria en sus raíces históricas. Estudio de caso: Alicante en el siglo XVIII
Authors: Bueno Vergara Eduardo , Perdiguero Gil Enrique
Published: February 2017

El presente trabajo analiza el papel que desempeñaron los médicos como agentes de lucha contra la enfermedad en la ciudad de Alicante durante el siglo XVIII. El ayuntamiento alicantino contaba con tres médicos asalariados para atender a la población. La contratación municipal de dicho personal sanitario era una práctica habitual, a través de la cual, los médicos adquirían una serie de responsabilidades, siendo la asistencia a domicilio la principal de ellas. Sin embargo, la presencia de estos tres médicos titulares no fue suficiente para atender a toda la población, algo que quedó reflejado en las constantes protestas de los vecinos por la ausencia de los facultativos. Además de los contratados, también existían otros médicos que ejercían en la ciudad por libre. En nuestro análisis, al comparar las experiencias y circunstancias que caracterizaron el caso de la ciudad de Alicante en esta centuria con el de otras poblaciones que han sido objeto de estudio, encontramos algunas diferencias que deben ser explicadas en el marco de un contexto socioeconómico concreto.
Thermodynamic characterization of solidification and defects that occur in Mg-alloy AM60
Authors: Voncina M. , Petric M. , Mrvar P. , Medved J.
Published: February 2017

The AM60 alloy was thermodynamically examined using chemical analysis, thermodynamic calculation made by ThermoCalc program, ?in situ? thermal analysis and differential scanning calorimetry (DSC), whereas the microstructure constituents were confirmed using optical and scanning electron microscopy (SEM). At the eutectic temperature of 437 ?C the equilibrium solubility of Al in Mg is 12.6 wt. % Al. On the boundaries of the primary Mg grains the intermetallic compound of Al12Mg17 is precipitating according to the solvus line of the Mg-Al phase diagram. Solidification of the AM60 alloy has been investigated using ?in situ? simple thermal analysis. The investigation of solidification has been taking place by evaluation of the cooling curves in connection with metallographic examinations, differential scanning calorimetry and thermodynamic calculations. All defects, nonmetallic inclusions and intermetallic compounds that occur in investigated AM60 alloy were identified.
HUBUNGAN ANTARA KUALITAS LAYANAN PERPUSTAKAAN UNDIKSHA DAN KEPUASAN PENGGUNANYA
Authors: Dharma Nyoman Oka
Published: February 2017

Penelitian ini bertujuan untuk mengetahui hubungan kualitas pelayanan Perpustakaan Undiksha dengan kepuasan penggunanya. Pengukuran kualitas pelayanan berdasarkan pada lima dimensi kualitas pelayanan yang dikemukakan oleh Parasuraman,dkk, yaitu bukti langsung (tangible), keandalan (reliability), daya tanggap (responsiveness), jaminan (assurance), dan empati (empathy). Penelitian ini menggunakan pendekatan ex post facto. Sampel penelitian ini adalah mahasiswa Undiksha yang berkunjung ke perpustakaan Undiksha sebanyak 60 orang. Teknik pengambilan sampel menggunakan accidental random sampling. Data utama dalam penelitian ini dikumpulkan dengan menggunakan kuisioner, sedangkan data pendukungnya dikupulkan dengan observasi dan wawancara. Data yang telah terkumpul dianalisis dengan menggunakan analisis kuantitatif. Penelitian ini menemukan bahwa terdapat hubungan kualitas pelayanan terhadap kepuasan pengunjung perpustakaan Undiksha dilihat dari aspek bukti langsung (katagori agak rendah); kehandalan (katagori cukup); cepat tanggap (katagori tinggi); kepastian (katagori agak rendah); dan empati (katagori tinggi). Secara umum besarnya korelasi antara kualitas pelayanan terhadap kepuasan pengunjung r = 0,952 sedangkan kontribusinya sebesar 0,906 atau 90,60%, dimana hal ini diinterpretasikanke dalam katagori sangat kuat
Implementasi Quality Function Deployment (QFD) untuk Meningkatkan Layanan Publik di RSUD Kabupaten Buleleng Bali
Authors: Agus Jana Susila Gede Putu
Published: February 2017

Rumah sakit sebagai salah satu sarana kesehatan yang memberikan pelayanan kesehatan kepada masyarakat memiliki peran yang sangat strategis dalam mempercepat peningkatan derajat kesehatan masyarakat. Oleh karena itu, rumah sakit dituntut untuk memberikan pelayanan yang bermutu sesuai dengan standar yang ditetapkan dan dapat menjangkau seluruh lapisan masyarakat. Kepuasan pasien menjadi tolak ukur tingkat kualitas pelayanan kesehatan. Selain itu, kepuasan pasien merupakan satu elemen yang penting dalam mengevaluasi kualitas layanan dengan mengukur sejauh mana respon pasien setelah menerima jasa. Penelitian ini menggunakan analisis metode Quality Function Deployment untuk mengetahui atribut-atribut kepuasan yang diinginkan pasien, tingkat kepentingan, parameter teknik, kebutuhan proses dan prosedur kualitas. QFD diaplikasikan untuk menerjemahkan apa yang diinginkan oleh pasien ke dalam prosedur kualitas yang lebih terperinci. Hasil dari penelitian pada RSUD Kabupaten Buleleng dengan menggunakan QFD, didapatkan atribut-atribut kepuasan yang diinginkan oleh pasien dan diterjemahkan ke dalam parameter teknik dalam House of Quality (HOQ). Atribut-atribut yang merupakan prioritas untuk diperhatikan dan dipenuhi oleh pengelola RSUD Kabupaten Buleleng berdasarkan pembobotan dari masing-masing atribut tersebut, yaitu: ruang rawat inap yang bersih, tempat tidur yang nyaman, kamar mandi yang bersih, tempat ibadah yang bersih, ruang rawat inap yang sejuk dan tenang , ruang parkir yang aman dan memadai, jaminan peralatan medis yang steril, pelayanan yang cepat dan akurat, tenaga medis yang profesional  dan ruang parkir yang memadai dan aman.
IPTEKS BAGI WILAYAH (IbW) DI KECAMATAN GEROKGAK
Authors: Mardana Ida Bagus Putu
Published: February 2017

Kegiatan  IbW  yang  dilakukan  pada  tahun  II  (Tahun  2011)  adalah  melakukan pemetaan asset di wilayah garapan   dan melaksanakan program ipteks peningkatan pengetahuan dan keterampilan dalam pertanian-peternakan-perikanan, pendidikan life skill  dan  kewirausahaan,  dan  pembinaan  adat-istiadat,  keagamaan,  dan  lembaga sosial. Metode pelaksanaan IBW dalam pemberdayaan masyarakat miskin adalah metode PALS (participatory action learning system) yang bersendikan pada 3(tiga) tahapan kegiatan, yakni (1) tahap penyadaran (Awareness), (2) tahap pengkapasitasan/pendampingan (participating /scaffolding), dan (3) tahapan pelembagaan (institutionalization). Hasil kegiatan IbW pada tahun II (tahun 2011) adalah terwujudnya deplot setra industri pengolahan kelapa, demplot pertanian multikultur, demplot peternakan berbasis zero waste. Dampak yang ditimbulkan dari pelaksanaan program IbW tahun II adalah adanya peningkatan kesadaran masyarakat untuk   meningkatkan  kualitas   hidup   melalui   pelipatgandaan  aktivitas   ekonomi produktif masyarakat berpijak pada potensi dan kearifan lokal yang ada, dan peningkatan penguasaan  IPTEKS  untuk  meningkatkan kapasitas  dan  diversifikasi produksi hasil tani-ternak-perikanan
IbM BIOGAS
Authors: Mariawan I Made
Published: February 2017

Krisis energi yang membuat harga minyak dunia melonjak semakin menghimpit kehidupan masyarakat tani di pedesaan. Dalam situasi seperti ini, pencarian, pengembangan, dan penyebaran teknologi energi yang ramah lingkungan menjadi hal yang sangat penting, terutama keluarga miskin sebagai golongan yang banyak terkena dampak kenaikan BBM. Salah satu teknologi energi yang sesuai dengan persyaratan tersebut adalah teknologi biogas. Kegiatan ini, membangun satu unit teknologi biogas yang dilakukan bersama masyarakat desa melalui kegiatan IbM. Kegiatan ini dilakukan di Desa Wongaya Betan dengan melibatkan 4 kelompok tani ternak yang masing-masing anggotanya terdiri dari 4 orang. Hasil yang diperoleh adalah rancangan satu unit biogas sederhana dengan memanfaatkan limbah ternak. Kegiatan ini diperkirakan bisa berkembang selanjutnya mengingat potensi desa yang cukup potensial
PELATIHAN TEKNIK PENGGUNAAN BAHAN KIMIA UNTUK PENINGKATKAN KESELAMATAN KERJA DI LABORATORIUM KIMIA
Authors: Lasia I Ketut , Gunamantha I Made , Budiada I Ketut
Published: February 2017

Pelatihan ini bertujuan untuk meningkatkan keterampilan penggunaan bahan kimia, menambah  pengetahuan  sifat dan karakter bahan kimia yang memiliki  potensi  dapat menimbulkan bahaya baik terhadap kesehatan  maupun bahaya kecelakaan, dan dapat meningkatkan budaya keselamatan dan keamanan. Sasaran kegiatan ini adalah mahasiswa semester awal Jurusan Pendidikan Kimia FMIPA Undiksha. Untuk mencapai tujuan tersebut maka digunakan metode pendampingan dengan praktek dan diskusi. Data hasil kegiatan dideskripsikan  secara aktual dan sistematis dalam kontek analisis deskriptif. Hasil yang diperoleh terjadi peningkatan keterampilan penggunaan bahan kimia, penambahan  pengetahuan  tentang sifat dan karakter  bahan  kimia yang berbahaya bagi kesehatan, dan mulai tercipta budaya keselamatan dan keamanan dalam praktikum kimia
PELATIHAN PENYUSUNAN RPP BERMUATAN PENDIDIKAN KARAKTER PADA GURU-GURU DI SEKOLAH DASAR NOMOR 1 KAPAL
Authors: Nurjaya I Gede
Published: February 2017

Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan kemampuan guru- guru di SD Nomor 1 Kapal Badung dalam menyusun  RPP bermuatan  karakter yang terarah dan sistematis, melalui pelatihan. Pelaksanaan pelatihan dibagi menjadi 3 sesi yaitu sesi pertama pemaparan tentang hakikat RPP dan pendidikan karakter, dilanjutkan tanya jawab, dan kedua pendampingan latihan menyusun RPP, dan sesi ketiga berupa implementasi RPP pada pembelajaran di kelas. Hasil yang ditemukan adalah (1) peserta pelatihan sangat antusias mengikuti pelatihan, (2) rata-rata skor penyusunan RPP oleh guru SDN 1 Kapal adalah 32,5 ( N = 40) setara dengan nilai 81 pada skala 100, (3) sebagian besar peserta pelatihan (80%) berhasil menyusun sebuah RPP bermuatan pendidikan karakter.
PELATIHAN PENYUSUNAN GUIDE BOOK POKDARWIS TUNJUNG MEKARDI DESA SAMBANGAN
Authors: Andiani Dini
Published: February 2017

Kegiatan Pengabdian  Pada Masyarakat  (P2M) yang dilaksanakan ini bertujuan untuk memberikan pelatihan pembuatan guide book yang akan mampu memudahkan para anggota   POKDARWIS  untuk   menjadi   pemandu   wisata   yang   bisa   memberikan informasi  yang tepat mengenai  kondisi  jalur trekking  dalam bahasa  inggris.  Melalui kegiatan ini, anggota POKDARWIS  memiliki acuan untuk menjadi guide lokal yang profesional. Metode yang digunakan dalam Program Pengabdian pada Masyarakat ini adalah   metode kerja kolaborasi antara dosen, dan masyarakat sasaran (dalam hal ini adalah anggota POKDARWIS Tunjung Mekar). Di samping itu, dalam melaksanakan Program Pengabdian pada  Masyarakat  ini,  pada  awalnya  dilakukan  analisis  situasi melalui beberapa kali observasi dan wawancara dengan pihak mitra, beberapa metode yang  digunakan  dalam  melaksanakan proram  ini  seperti  metode  penyuluhan  dan pelatihan, metode wawancara.
Assembling Local Cyclone Knowledge in the Australian Tropics
Authors: Swee Hannah
Published: February 2017

In Far North Queensland, a region in the northeast of Australia, cyclones are an annual risk. As a result of this frequency of cyclonic activity, different forms of cyclone knowledge exist ranging from disaster management information to local conceptualizations. For the people that inhabit this region, cyclones are a lived reality that are known in different, seemingly contradictory ways. Drawing on fifteen months of ethnographic fieldwork conducted in Far North Queensland from 2012 to 2015, this article explores how local cyclone knowledge is assembled from a variety of heterogeneous factors that change and fluctuate through time, and are subject to an ongoing process of evaluation.
Rainbows of Resistance: LGBTQ Pride Parades Contesting Space in Post-Conflict Belfast
Authors: Drissel William David
Published: February 2017

The article seeks to demonstrate how marchers in the annual LGBTQ Pride Parade strategically contest and reclaim heteronormative public spaces in Belfast, Northern Ireland. There is an exploration of participants adapting transnational symbolic representations and discourses to the distinct national-local cultural milieu in which they are scripted and performed. The discursive frames, symbols, and performances of Belfast Pride are compared to those of sectarian parades in the city. The subaltern spatial performances and symbolic representations of Belfast Pride are depicted as confronting a universalized set of heteronormative discourses involving sexuality and gender identity, while at the same time contesting a particularized set of dominant local-national discourses related to both ethnonational sectarianism and religious fundamentalism in Northern Ireland.
Negotiating identities through the ‘cultural practice’ of labia elongation among urban Shona women and men in contemporary Zimbabwe
Authors: Venganai Hellen
Published: February 2017

Dominant Eurocentric discourses on African traditional cultural practices linked to sexuality construct these practices as retrogressive for women in these localities. These discourses take the form of women and sexual rights promoted by some women activists and scholars, whose work mainly focuses on the so-called traditional rural women as victims of these gendered sexual practices. In many ways, such approaches manufacture and exaggerate differences between Western and African women, while reproducing colonial discourses that construct Africans as backward. This article interrogates the modern-traditional binary which underpin conventional representations of some sexual practices as cultural. Following African feminist scholars who argue for research which explores the significance and meanings such sexual practices hold for those women who engage in them, this article draws on a study I conducted with Shona speaking women and men in Zimbabwe who participated and/or were interested in the practice of labia elongation. The targeted women and men, in their 20s -30s, live in relatively affluent houses in Harare, and are identified as urban, modern and middle-class. The study sought to explore why such women (as well as men) who identify as modern were so interested and invested in a sexual practice that has often been constructed as traditional and cultural. By exploring how women and men invoke notions of culture and tradition, the article demonstrates the creative and complex ways in which the young adults position themselves in relation to this practice in particular, and in relation to gender and sexuality more generally.
Selective Feeding and Microalgal Consumption Rates by Crown-Of-Thorns Seastar (Acanthaster cf. solaris) Larvae
Authors: Mellin Camille , Lugrin Claire , Okaji Ken , Francis David , Uthicke Sven
Published: February 2017

Outbreaks of the crown-of-thorns seastar (CoTS) represent a major cause of coral loss on the Great Barrier Reef. Outbreaks can be explained by enhanced larval survival supported by higher phytoplankton availability after flood events, yet little is known about CoTS larvae feeding behaviour, in particular their potential for selective feeding. Here, single- and mixed-species feeding experiment were conducted on CoTS larvae using five algae (Phaeodactylum tricornutum, Pavlova lutheri, Tisochrysis lutea, Dunaliella sp. and Chaetoceros sp.) and two algal concentrations (1000 and 2500 algae·mL−1). Cell counts using flow-cytometry at the beginning and end of each incubation experiment allowed us to calculate the filtration and ingestion rates of each species by CoTS larvae. In line with previous studies, CoTS larvae ingested more algae when the initial algal concentration was higher. We found evidence for the selective ingestion of some species (Chaetoceros sp., Dunaliella sp.) over others (P. lutheri, P. tricornutum). The preferred algal species had the highest energy content, suggesting that CoTS selectively ingested the most energetic algae. Ultimately, combining these results with spatio-temporal patterns in phytoplankton communities will help elucidate the role of larval feeding behaviour in determining the frequency and magnitude of CoTS outbreaks.
Zinc Transporter 3 (ZnT3) in the Enteric Nervous System of the Porcine Ileum in Physiological Conditions and during Experimental Inflammation
Authors: Gonkowski Sławomir , Rowniak Maciej , Wojtkiewicz Joanna
Published: February 2017

Zinc transporter 3 (ZnT3) is a member of the solute-linked carrier 30 (SLC 30) zinc transporter family. It is closely linked to the nervous system, where it takes part in the transport of zinc ions from the cytoplasm to the synaptic vesicles. ZnT3 has also been observed in the enteric nervous system (ENS), but its reactions in response to pathological factors remain unknown. This study, based on the triple immunofluorescence technique, describes changes in ZnT3-like immunoreactive (ZnT3-LI) enteric neurons in the porcine ileum, caused by chemically-induced inflammation. The inflammatory process led to a clear increase in the percentage of neurons immunoreactive to ZnT3 in all “kinds” of intramural enteric plexuses, i.e., myenteric (MP), outer submucous (OSP) and inner submucous (ISP) plexuses. Moreover, a wide range of other active substances was noted in ZnT3-LI neurons under physiological and pathological conditions, and changes in neurochemical characterisation of ZnT3+ cells in response to inflammation depended on the “kind” of enteric plexus. The obtained results show that ZnT3 is present in the ENS in a relatively numerous and diversified neuronal population, not only in physiological conditions, but also during inflammation. The reasons for the observed changes are not clear; they may be connected with the functions of zinc ions and their homeostasis disturbances in pathological processes. On the other hand, they may be due to adaptive and/or neuroprotective processes within the pathologically altered gastrointestinal tract.
Anti-Inflammatory Activity of Sanghuangporus sanghuang Mycelium
Authors: Lin Wang-Ching , Deng Jeng-Shyan , Huang Shyh-Shyun , Wu Sheng-Hua , Chen Chin-Chu , Lin Wan-Rong , Lin Hui-Yi , Huang Guan-Jhong
Published: February 2017

Acute lung injury (ALI) is characterized by inflammation of the lung tissue and oxidative injury caused by excessive accumulation of reactive oxygen species. Studies have suggested that anti-inflammatory or antioxidant agents could be used for the treatment of ALI with a good outcome. Therefore, our study aimed to test whether the mycelium extract of Sanghuangporus sanghuang (SS-1), believed to exhibit antioxidant and anti-inflammatory properties, could be used against the excessive inflammatory response associated with lipopolysaccharides (LPS)-induced ALI in mice and to investigate its possible mechanism of action. The experimental results showed that the administration of SS-1 could inhibit LPS-induced inflammation. SS-1 could reduce the number of inflammatory cells, inhibit myeloperoxidase (MPO) activity, regulate the TLR4/PI3K/Akt/mTOR pathway and the signal transduction of NF-κB and MAPK pathways in the lung tissue, and inhibit high mobility group box-1 protein 1 (HNGB1) activity in BALF. In addition, SS-1 could affect the synthesis of antioxidant enzymes Heme oxygenase 1 (HO-1) and Thioredoxin-1 (Trx-1) in the lung tissue and regulate signal transduction in the KRAB-associated protein-1 (KAP1)/nuclear factor erythroid-2-related factor Nrf2/Kelch Like ECH associated Protein 1 (Keap1) pathway. Histological results showed that administration of SS-1 prior to induction could inhibit the large-scale LPS-induced neutrophil infiltration of the lung tissue. Therefore, based on all experimental results, we propose that SS-1 exhibits a protective effect against LPS-induced ALI in mice. The mycelium of S. sanghuang can potentially be used for the treatment or prevention of inflammation-related diseases.
Synthesis, Crystal Structure, Polymorphism, and Magnetism of Eu(CN3H4)2 and First Evidence of EuC(NH)3
Authors: Görne Arno , George Janine , Van Leusen Jan , Dronskowski Richard
Published: February 2017

We report the first magnetically coupled guanidinate, α-Eu(CN3H4)2 (monoclinic, P21, a = 5.8494(3) Å, b = 14.0007(8) Å, c = 8.4887(4) Å, β = 91.075(6)°, V = 695.07(6) Å3, Z = 4). Its synthesis, polymorphism, crystal structure, and properties are complemented and supported by density-functional theory (DFT) calculations. The α-, β- and γ-polymorphs of Eu(CN3H4)2 differ in powder XRD, while the γ-phase transforms into the β-form over time. In α-Eu(CN3H4)2, Eu is octahedrally coordinated and sits in one-dimensional chains; the guanidinate anions show a hydrogen-bonding network. The different guanidinate anions are theoretically predicted to adopt syn-, anti- and all-trans-conformations. Magnetic measurements evidence ferromagnetic interactions, presumably along the Eu chains. Finally, EuC(NH)3 (isostructural to SrC(NH)3 and YbC(NH)3, hexagonal, P63/m, a = 5.1634(7) Å, c = 7.1993(9) Å, V = 166.23(4) Å3, Z = 2) is introduced as a possible ferromagnet.
Sensor Pods: Multi-Resolution Surveys from a Light Aircraft
Authors: Cahalane Conor , Walsh Daire , Magee Aidan , Mannion Sean , Lewis Paul , McCarthy Tim
Published: February 2017

Airborne remote sensing, whether performed from conventional aerial survey platforms such as light aircraft or the more recent Remotely Piloted Airborne Systems (RPAS) has the ability to compliment mapping generated using earth-orbiting satellites, particularly for areas that may experience prolonged cloud cover. Traditional aerial platforms are costly but capture spectral resolution imagery over large areas. RPAS are relatively low-cost, and provide very-high resolution imagery but this is limited to small areas. We believe that we are the first group to retrofit these new, low-cost, lightweight sensors in a traditional aircraft. Unlike RPAS surveys which have a limited payload, this is the first time that a method has been designed to operate four distinct RPAS sensors simultaneously—hyperspectral, thermal, hyper, RGB, video. This means that imagery covering a broad range of the spectrum captured during a single survey, through different imaging capture techniques (frame, pushbroom, video) can be applied to investigate different multiple aspects of the surrounding environment such as, soil moisture, vegetation vitality, topography or drainage, etc. In this paper, we present the initial results validating our innovative hybrid system adapting dedicated RPAS sensors for a light aircraft sensor pod, thereby providing the benefits of both methodologies. Simultaneous image capture with a Nikon D800E SLR and a series of dedicated RPAS sensors, including a FLIR thermal imager, a four-band multispectral camera and a 100-band hyperspectral imager was enabled by integration in a single sensor pod operating from a Cessna c172. However, to enable accurate sensor fusion for image analysis, each sensor must first be combined in a common vehicle coordinate system and a method for triggering, time-stamping and calculating the position/pose of each sensor at the time of image capture devised. Initial tests were carried out over agricultural regions with geometric tests designed to assess the spatial accuracy of the fused imagery in terms of its absolute and relative accuracy. The results demonstrate that by using our innovative system, images captured simultaneously by the four sensors could be geometrically corrected successfully and then co-registered and fused exhibiting a root-mean-square error (RMSE) of approximately 10m independent of inertial measurements and ground control.
On the Power and Size Properties of Cointegration Tests in the Light of High-Frequency Stylized Facts
Authors: Krauss Christopher , Herrmann Klaus
Published: February 2017

This paper establishes a selection of stylized facts for high-frequency cointegrated processes, based on one-minute-binned transaction data. A methodology is introduced to simulate cointegrated stock pairs, following none, some or all of these stylized facts. AR(1)-GARCH(1,1) and MR(3)-STAR(1)-GARCH(1,1) processes contaminated with reversible and non-reversible jumps are used to model the cointegration relationship. In a Monte Carlo simulation, the power and size properties of ten cointegration tests are assessed. We find that in high-frequency settings typical for stock price data, power is still acceptable, with the exception of strong or very frequent non-reversible jumps. Phillips–Perron and PGFF tests perform best.
Intramolecular Hydrogen Bonds in Conformers of Quinine and Quinidine: An HF, MP2 and DFT Study
Authors: Bilonda Mireille , Mammino Liliana
Published: February 2017

Quinine is an alkaloid with powerful antimalarial activity, isolated from the bark of Peru’s cinchona trees. Quinidine is an erythro diastereoisomer of quinine also exhibiting antimalarial activity. Conformational studies performed so far had never identified conformers with intramolecular hydrogen bonds (IHB). The current study shows the possibility of conformers with an IHB between the quinuclidine and quinoline moieties of these molecules. The study was performed at different levels of theory: Hartree Fock (HF) with the 6-31G(d,p) basis set, Density Functional Theory (DFT) with the B3LYP functional and the 6-31+G(d,p) basis set and Møller–Plesset Perturbation Theory (MP2) with the 6-31+G(d,p) basis set, to confirm the results. The results suggest that the stabilising effect of this IHB is weaker or comparable with respect to the stabilising effect of the preferred mutual orientation of the two moieties. Although the IHB-containing conformers may not be the lowest energy ones, their relative energy is sufficiently low for them to be included among the possible ones responsible for the compounds’ antimalarial activity.
Poloxamer-Based Thermoreversible Gel for Topical Delivery of Emodin: Influence of P407 and P188 on Solubility of Emodin and Its Application in Cellular Activity Screening
Authors: Ban Eunmi , Park Mijung , Jeong Seonghee , Kwon Taekhyun , Kim Eun-Hee , Jung Kiwon , Kim Aeri
Published: February 2017

Emodin is a component in a Chinese herb, Rheum officinale Baill, traditionally used for diabetes and anticancer. Its poor solubility is one of the major challenges to pharmaceutical scientists. We previously reported on thermoreversible gel formulations based on poloxamer for the topical delivery of emodin. The present study was to understand the effect of poloxamer type on emodin solubility and its application in cellular activity screening. Various gel formulations composed of poloxamer 407 (P407), poloxamer 188 (P188) and PEG400 were prepared and evaluated. Major evaluation parameters were the gelation temperature (Tgel) and solubility of emodin. The emodin solubility increased with increasing poloxamer concentration and the Tgel was modulated by the proper combination of P407. In particular, this study showed that the amount of P407 in thermoreversible poloxamer gel (PG) was the dominant factor in enhancing solubility and P188 was effective at fixing gelation temperature in the desired range. A thermoreversible emodin PG was selected as the proper composition with the liquid state at room temperature and gel state at body temperature. The gel showed the solubility enhancement of emodin at least 100-fold compared to 10% ethanol or water. The thermoreversible formulation was applied for in vitro cellular activity screening in the human dermal fibroblast cell line and DLD-1 colon cancer cell line after dilution with cell culture media. The thermoreversible gel formulation remained as a clear solution in the microplate, which allowed reliable cellular activity screening. In contrast, emodin solution in ethanol or DMSO showed precipitation at the corresponding emodin concentration, complicating data interpretation. In conclusion, the gel formulation is proposed as a useful prototype topical formulation for testing emodin in vivo as well as in vitro.
A Signal Processing Approach with a Smooth Empirical Mode Decomposition to Reveal Hidden Trace of Corrosion in Highly Contaminated Guided Wave Signals for Concrete-Covered Pipes
Authors: Rostami Javad , Chen Jingming , Tse Peter
Published: February 2017

Ultrasonic guided waves have been extensively applied for non-destructive testing of plate-like structures particularly pipes in past two decades. In this regard, if a structure has a simple geometry, obtained guided waves’ signals are easy to explain. However, any small degree of complexity in the geometry such as contacting with other materials may cause an extra amount of complication in the interpretation of guided wave signals. The problem deepens if defects have irregular shapes such as natural corrosion. Signal processing techniques that have been proposed for guided wave signals’ analysis are generally good for simple signals obtained in a highly controlled experimental environment. In fact, guided wave signals in a real situation such as the existence of natural corrosion in wall-covered pipes are much more complicated. Considering pipes in residential buildings that pass through concrete walls, in this paper we introduced Smooth Empirical Mode Decomposition (SEMD) to efficiently separate overlapped guided waves. As empirical mode decomposition (EMD) which is a good candidate for analyzing non-stationary signals, suffers from some shortcomings, wavelet transform was adopted in the sifting stage of EMD to improve its outcome in SEMD. However, selection of mother wavelet that suits best for our purpose plays an important role. Since in guided wave inspection, the incident waves are well known and are usually tone-burst signals, we tailored a complex tone-burst signal to be used as our mother wavelet. In the sifting stage of EMD, wavelet de-noising was applied to eliminate unwanted frequency components from each IMF. SEMD greatly enhances the performance of EMD in guided wave analysis for highly contaminated signals. In our experiment on concrete covered pipes with natural corrosion, this method not only separates the concrete wall indication clearly in time domain signal, a natural corrosion with complex geometry that was hidden and located inside the concrete section was successfully exposed.
Une occupation de la phase ancienne du Paléolithique moyen à Therdonne (Oise). Chronostratigraphie, production de pointes Levallois et réduction des nucléus
Authors: Locht Jean-Luc , Antoine Pierre , Hérisson David , Gadebois Guillaume , Debenham Nick
Published: February 2017

À la fin du stade isotopique 7, vers 170-190 ka BP, les Préhistoriques sont venus s’installer sur le pied de versant de la butte tertiaire du mont de Bourguillemont à Therdonne (Oise). Situé à moins de 4 km du gisement paléolithique moyen récent de la Justice à Beauvais (Oise), le site de Therdonne offre les mêmes avantages propices à l’installation de groupes paléolithiques. La fouille préventive du gisement a notamment livré un niveau archéologique N3, à l’état de conservation exceptionnel. Cet article a pour objectif de poser le cadre chronostratigraphique du gisement et de présenter les premiers résultats concernant l’étude du niveau archéologique N3, et plus particulièrement l’étude des pointes Levallois, un des principaux objectifs de production de l’occupation. Ce gisement s’intègre dans le cadre archéologique pauvre en découvertes de la phase ancienne du Paléolithique moyen, ce qui fait de l’occupation N3 un des rares témoignages, bien calé chronologiquement, attribuables au Saalien.
Identité technique et comportements économiques des groupes proto-aurignaciens à la grotte de l’Observatoire (principauté de Monaco)
Authors: Porraz Guillaume , Simon Patrick , Pasquini Amaranta
Published: February 2017

Cet article présente de premiers résultats et réflexions sur l’assemblage lithique proto-aurignacien de la grotte de l’Observatoire (principauté de Monaco) et fait valoir l’intérêt de ce contexte régional pour l’étude de la diffusion du Paléolithique supérieur en Europe occidentale. Cette étude confirme l’attribution des niveaux G et F au complexe proto-aurignacien (Onoratini et al., 1999). Les chaînes opératoires lithiques se caractérisent par une acquisition sélective de roches de très bonne qualité, par la coexistence de deux schémas de production unipolaire, l’un laminaire, l’autre lamellaire, et par une confection de lamelles à dos par retouche inverse dextre (lamelle Dufour, soustype Dufour). Ces caractéristiques sont proches de celles aujourd’hui décrites dans la littérature, laissant ainsi entrevoir l’homogénéité technique de ce complexe à l’échelle de l’Europe occidentale. Le profil de cet assemblage caractérise des occupations de courte durée, renvoyant à des stratégies de subsistance basées sur une forte mobilité résidentielle et de longs déplacements (> 130 km). Dans cette perspective, les données techno-économiques se prêtent à l’hypothèse d’un complexe technoculturel porté par des nouvelles populations qui auraient circulé le long de l’espace méditerranéen. La localisation principale des gîtes d’approvisionnement en matières premières (85 % de silex bédouliens et oligocènes de Provence occidentale) nuancerait alors l’hypothèse d’une avancée continue des premiers hommes anatomiquement modernes en Europe, privilégiant plutôt le scénario d’une progression ponctuée de stases.
Étude tracéologique de l’outillage moustérien de type Quina du bonebed de Chez-Pinaud à Jonzac (Charente-Maritime). Nouveaux éléments en faveur d’un site de boucherie et de traitement des peaux
Authors: Claud Émilie , Soressi Marie , Jaubert Jacques , Hublin Jean-Jacques
Published: February 2017

L’industrie lithique du Moustérien de type Quina de Chez-Pinaud à Jonzac, en Charente-Maritime, est originale. Elle est fondée sur la production de supports bifaciaux par percussion marginale alors que le Moustérien de type Quina est connu pour son débitage de supports courts et épais par percussion interne. Par ailleurs, cette industrie est ici associée à une exceptionnelle accumulation d’ossements (bonebed). Les premières analyses montrent que ce site aurait été utilisé comme un lieu d’exploitation saisonnière du Renne. L’étude des traces d’utilisation permet d’apporter de nouveaux éléments sur la fonction du site au Moustérien de type Quina. Plusieurs centaines de pièces ont été observées à la loupe binoculaire à la recherche de traces d’utilisation, à l’issue de quoi 98 ont fait l’objet d’un examen complet, à l’échelle macro-et microscopique. L’échantillon retenu se compose d’éléments issus de différents moments de la chaîne opératoire de production Quina, retouchés ou non. Les modes de fonctionnement mis en évidence sont la coupe de matière carnée et cutanée, et la percussion contre des matières dures, organiques et minérales, ce qui indique la mise en oeuvre sur le site d’activités de boucherie (en coupe et percussion) et de travail de la peau fraîche. Cette analyse apporte. donc de nouveaux éléments compatibles avec une utilisation du site comme un atelier de traitement primaire des carcasses. Les parallèles entre les modes de fonctionnement des outils analysés et leurs caractéristiques techno-typologiques permettent d’apporter un nouvel éclairage sur la signification de l’opération de «dénaturation » des racloirs, qui semble succéder dans plusieurs cas à une utilisation des racloirs pour percuter des matières dures.
Identification and characterization of microsatellite markers in Pinus kesiya var. langbianensis (Pinaceae)
Authors: Cai Nian‐Hui , Xu Yu‐Lan , Wang Da‐Wei , Chen Shi , Li Gen‐Qian
Published: February 2017

Premise of the study:

Microsatellite primers were developed in Pinus kesiya var. langbianensis (Pinaceae), a species native to southwestern China, to investigate its genetic diversity and population structure in order to provide information for the conservation and management of this species.

Methods and Results:

Using next‐generation sequencing, a total of 2349 putative simple sequence repeat primer pairs were designed. Eighteen polymorphic markers in 60 individuals belonging to four populations of P. kesiya var. langbianensis were identified and characterized with two to 11 alleles per locus. The observed and expected heterozygosity ranged from 0.000 to 0.800 and 0.000 to 0.840, respectively. Each of these loci cross‐amplified in the closely related species P. massoniana, P. densata, P. tabuliformis, and P. yunnanensis, with one to seven alleles per locus.

Conclusions:

The new markers are promising tools to study the population genetics of P. kesiya var. langbianensis and related species.
Continuous-flow synthesis of highly functionalized imidazo-oxadiazoles facilitated by microfluidic extraction
Authors: Herath Ananda , Cosford Nicholas D P
Published: February 2017

A versatile continuous-flow synthesis of highly functionalized 1,2,4-oxadiazoles starting from carboxylic acids is reported. This process was applied to the multistep synthesis of imidazo[1,2-a]pyridin-2-yl-1,2,4-oxadiazoles, using a three reactor, multistep continuous-flow system without isolation of intermediates. This continuous-flow method was successfully combined with a single-step liquid–liquid microextraction unit to remove high boiling point polar solvents and impurities and provides the target compounds in high purity with excellent overall yields.
An analysis of road pavement collapses and traffic safety hazards resulting from leaky sewers
Authors: Kuliczkowska Emilia
Published: February 2017

In this paper, road pavement collapses resulting from sewer leakage are divided into six categories: negligible,
marginal, considerable, serious, very serious and catastrophic, with the categorization being based on two criteria, both
related to traffic safety, i.e., the number of fatalities caused by sinkholes, and the extent of the road pavement damage.
The causes of road pavement collapses are also discussed. The study involved analyzing the deterioration of sewer pipes
with long service lives, focusing on the most common materials, i.e., concrete and vitrified clay. The results of the sewer
inspections performed by the Kielce University of Technology suggest that the spot and linear defects detected in sewers
of this type can be divided into three groups. The findings were used to formulate some recommendations on how to
improve road traffic safety by preventing road pavement collapses.
Determination of load equivalency factors by statistical analysis of weigh-in-motion data
Authors: Soós Zoltán , Tóth Csaba , Bóka Dávid
Published: February 2017

The load equivalency factors for pavement design currently in use by the Hungarian standard have been developed using Weigh-in-Motion data obtained during the first few years of operations after installing some 30 measuring sites in Hungary in 1996. In the past years, and currently, data is collected mainly at the border crossings of the country, however the data is used only for law enforcement purposes, and no comprehensive statistical analyses have been done. To develop actual load equivalency factors for the use in pavement design, data of one year was collected and statistical methods were applied. An algorithm was used to help managing the multimodal distribution of axle loads in mathematical perspectives. Monte-Carlo methods were applied to determine the factors for each heavy vehicle type and eventually for each vehicle class used by the current Hungarian pavement design manual. The calculated factors are considerably different from the current ones, indicating that the pavement design may lead to a false result. Furthermore, there are three vehicle types suggested to be incorporated into the standard due to their high occurrence.
Continued Kinematic and Photometric Investigations of Hierarchical Solar-type Multiple Star Systems
Authors: Roberts Lewis C. , Tokovinin Andrei , Mason Brian D. , Marinan Anne D.
Published: February 2017

We observed 15 of the solar-type binaries within 67 pc of the Sun previously observed by the Robo-AO system in the visible, with the PHARO near-infrared camera and the PALM-3000 adaptive optics system on the 5 m Hale telescope. The physical status of the binaries is confirmed through common proper motion and detection of orbital motion. In the process, we detected a new candidate companion to HIP 95309. We also resolved the primary of HIP 110626 into a close binary, making that system a triple. These detections increase the completeness of the multiplicity survey of the solar-type stars within 67 pc of the Sun. Combining our observations of HIP 103455 with archival astrometric measurements and RV measurements, we are able to compute the first orbit of HIP 103455, showing that the binary has a 68 year period. We place the components on a color–magnitude diagram and discuss each multiple system individually.
A Matched Filter Technique for Slow Radio Transient Detection and First Demonstration with the Murchison Widefield Array
Authors: Feng L. , Vaulin R. , Hewitt J. N. , Remillard R. , Kaplan D. L. , Murphy Tara , Kudryavtseva N. , Hancock P. , Bernardi G. , Bowman J. D. , Briggs F. , Cappallo R. J. , Deshpande A. A. , Gaensler B. M. , Greenhill L. J. , Hazelton B. J. , Johnston-Hollitt M. , Lonsdale C. J. , McWhirter S. R. , Mitchell D. A. , Morales M. F. , Morgan E. , Oberoi D. , Ord S. M. , Prabu T. , Shankar N. Udaya , Srivani K. S. , Subrahmanyan R. , Tingay S. J. , Wayth R. B. , Webster R. L. , Williams A. , Williams C. L.
Published: February 2017

Many astronomical sources produce transient phenomena at radio frequencies, but the transient sky at low frequencies (<300 MHz) remains relatively unexplored. Blind surveys with new wide-field radio instruments are setting increasingly stringent limits on the transient surface density on various timescales. Although many of these instruments are limited by classical confusion noise from an ensemble of faint, unresolved sources, one can in principle detect transients below the classical confusion limit to the extent that the classical confusion noise is independent of time. We develop a technique for detecting radio transients that is based on temporal matched filters applied directly to time series of images, rather than relying on source-finding algorithms applied to individual images. This technique has well-defined statistical properties and is applicable to variable and transient searches for both confusion-limited and non-confusion-limited instruments. Using the Murchison Widefield Array as an example, we demonstrate that the technique works well on real data despite the presence of classical confusion noise, sidelobe confusion noise, and other systematic errors. We searched for transients lasting between 2 minutes and 3 months. We found no transients and set improved upper limits on the transient surface density at 182 MHz for flux densities between ∼20 and 200 mJy, providing the best limits to date for hour- and month-long transients.
Galactic Structure in the Outer Disk: The Field in the Line of Sight to the Intermediate-Age open Cluster Tombaugh 1*
Authors: Carraro Giovanni , Silva Joao Victor Sales , Bidin Christian Moni , Vazquez Ruben A.
Published: February 2017

We employ optical photometry and high-resolution spectroscopy to study a field toward the open cluster Tombaugh 1, where we identify a complex population mixture that we describe in terms of young and old Galactic thin disks. Of particular interest is the spatial distribution of the young population, which consists of dwarfs with spectral types as early as B6 and is distributed in a blue plume feature in the color–magnitude diagram. For the first time, we confirm spectroscopically that most of these stars are early-type stars and not blue stragglers or halo/thick-disk subdwarfs. Moreover, they are not evenly distributed along the line of sight but crowd at heliocentric distances between 6.6 and 8.2 kpc. We compare these results with present-day understanding of the spiral structure of the Galaxy and suggest that they trace the outer arm. This range of distances challenges current Galactic models adopting a disk cutoff at 14 kpc from the Galactic center. The young dwarfs overlap in space with an older component, which is identified as an old Galactic thin disk. Both young and old populations are confined in space since the disk is warped at the latitude and longitude of Tombaugh 1. The main effects of the warp are that the line of sight intersects the disk and entirely crosses it at the outer arm distance and that there are no traces of the closer Perseus arm, which would then be either unimportant in this sector or located much closer to the formal Galactic plane. Finally, we analyze a group of giant stars, which turn out to be located at very different distances and to possess very different chemical properties, with no obvious relation to the other populations.
Infrared Spectra of Hexa-peri-hexabenzocoronene Cations: HBC+ and HBC2+
Authors: Zhen Junfeng , Castellanos Pablo , Bouwman Jordy , Linnartz Harold , Tielens Alexander G. G. M.
Published: February 2017

We present the first infrared (IR) gas-phase spectrum of a large and astronomically relevant polycyclic aromatic hydrocarbon (PAH) cation (C42H18
+, HBC+) and its dication (C42H18

, HBC2+). The spectra are recorded via infrared multiphoton dissociation (IRMPD) spectroscopy of ions stored in a quadrupole ion trap, using the intense IR radiation of a free electron laser in the 530–1800 cm−1 (5.6–18.9 μm) range. HBC+ shows main intense absorption peaks at 762 (13.12), 1060 (9.43), 1192 (8.39), 1280 (7.81), 1379 (7.25), and 1530 (6.54) cm−1 (μm), in good agreement with density functional theory calculations after scaling to take the anharmonicities effect into account. HBC2+ has its main absorption peaks at 660 (15.15), 766 (13.05), 1054 (9.49), 1176 (8.50), 1290 (7.75), 1370 (7.30) and 1530 (6.54) cm−1 (μm). Given the similarity in the cationic and dicationic spectra, we have not identified an obvious diagnostic signature to the presence of multiply charged PAHs in space. While experimental issues associated with the IRMPD technique preclude a detailed comparison with interstellar spectra, we do note that the strong bands of HBC+ and HBC2+ at ∼6.5, 7.7, 8.4, and 13.1 μm coincide with prominent aromatic infrared bands (AIBs). HBC has only trio CH groups, and the out-of-plane CH bending mode of both HBC cations is measured at 13.1 μm, squarely in the range predicted by theory and as previously found in studies of small (substituted) PAHs. This study therefore supports the use of AIBs observed in the 11–14 μm range as a diagnostic tool for the edge topology of large PAHs in space.