bluuebunny/crossref_metadata_2025 huggingface dataset:
Vulnerability and Risk Assessment of a State University in the Philippines
Authors: Badajos Marc Alexei Caesar B. , Caelian Merlita V.
Published: February 2021

This descriptive comparative research determined the vulnerability and risk index including the adaptive capacity of the university exposed elements: population, natural resources, and facilities. A researcher-made survey questionnaire was used to determine the adaptive capacity of these elements and was administered to 598 respondents composed of students, faculty, and non-teaching personnel from the three campuses. An assessment survey was also conducted over three groups of purposively selected students, personnel, and external stakeholders for vulnerability and risk. Using descriptive and inferential analysis, the study yielded a high adaptive capacity for all exposed elements and a significant difference when the respondents were grouped into campuses. Likewise, all campuses have a very low vulnerability and low risk to landslide but have a different risk to flooding: B has a high risk, A is moderate, while C has no risk. Findings suggest that each campus has to be treated differently to address priority areas.
Spiritual Well-Being and Resiliency of the Diocesan Seminarians of Antique
Authors: Legada Eric L. , Madrigal Dennis V. , Maravilla Ma. Wilma M.
Published: February 2021

Spiritual well-being is integral in seeking meaning and purpose in life. Related to this is resiliency, which is a dynamic attribute of bouncing back from difficult situations. Thus, this descriptive-correlational study determines the degree of spiritual well-being and the level of resiliency of the diocesan seminarians of Antique. Spiritual Well-being Scale and Resilience Scale standardized tests were used. The findings indicate that the degree of spiritual well-being of seminarians is high which indicates that the seminarians possess a certain degree of satisfaction and manifest a clear sense of purpose in life. On the other hand, the level of resiliency of the diocesan seminarians of Antique is "on the low end" which signifies that as a whole, they might be experiencing some depression and anxiety in their lives. Finally, there is a significant relationship between spirituality and resiliency. The study recommends designing an enhanced career guidance program for the formation of the seminarians.
Guided Quick Labs and Academically Challenged Learners’ Predicting, Observing, and Inferring Skills
Authors: Salanatin Martin John M.
Published: February 2021

This quasi-experimental study aimed at determining the effects of guided quick labs and traditional science laboratory activities on academically-challenged Grade 10 learners' predicting, observing, and inferring skills. The subjects in this study were the 60 academically-challenged Grade 10 learners of Antique National School in San Jose, Antique. The subjects were divided into two groups, the traditional and the quick labs. Pretest and post-test ware used to measure the predicting, observing, and inferring skills of the learners before and after exposure to both laboratory activities. The results showed that the predicting, observing, and inferring skills of the academically-challenged Grade 10 learners in both groups were comparable at the start of the six (6)-week intervention. After the intervention, the results revealed that both groups were still comparable. The findings proved that both types of laboratory activities have a similar effect in predicting and observing skills and is best improving the learners' inferring skills.
English Proficiency and Sequencing Skills in Narrative Writing of Public High School Students
Authors: Quijano Lester John T. , Legaspi Ma. Judy B.
Published: February 2021

This descriptive-comparative research explored the level of grammar proficiency and sequencing skills in narrative writing of the Grade 7 students. Specifically, it sought to determine the significant difference in the level of grammar proficiency and sequencing skills. The 308 Grade 7 students selected through stratified proportional sampling answered the researcher-made instrument. The findings revealed that the students have a low level of grammar proficiency and average level in sequencing skills as a whole. Moreover, a significant difference exists in the level of grammar proficiency and the level of sequencing skills of students when grouped according to academic performance in English and track, while no significant difference exists when the students are classified according to sex. The results imply that students can sequence events in a narrative. However, they find difficulty in writing grammatically correct sentences. With this, instructional materials may be designed to develop the students’ proficiency in writing.
Implementation of the Community Peace and Order and Public Safety Program in Negros Occidental, Philippines
Authors: Nicor-Mangilimutan Rhumyla G. , Mejica Maria Nove A. , Caelian Merlita V.
Published: February 2021

Peace is indivisible and global because it is the foundation of the survival of humanity. Ensuring peace and security of the people is vital in maintaining economic development, social order, and political stability. In the Philippines, the functionality of community peace and order and public safety (POPS) is strictly monitored by the government. This descriptive-comparative study assessed the extent of implementation of the POPS in terms of crime prevention and control, anti-illegal drugs, public safety, and enforcement of ordinances. It also investigated the differences in the implementation of the program when the communities are grouped according to variables.  Further, it explored the challenges and suggestions of community leaders. Using a researcher-made survey questionnaire, data were gathered from respondents. Findings revealed a great extent of implementation, but there were significant differences when barangays were grouped into variables. The findings were utilized as bases for an enhanced POPS program.
Consequences of COVID-19 Pandemic on Sleep, Psychological Immunity, and Wellbeing; Synchronized Lifestyle Modification Program: a Journey of Hope
Authors: Feroz Dr Shagufta , Khalid Samia , Jaffery Dr Mujtaba
Published: February 2021

Lifestyle is one of the most imperative factors concerned with the health and immune system. Due to the modern lifestyle and COVID-19, the lifestyle of the majority of Pakistani people has changed, therefore, they are facing the challenges of malnutrition, unhealthy food, and diet, physical illness, stress, anxiety, depression, and sleep disorder. Synchronized Life-style modification program (SLP) is an evidence-based exercise of serving individuals and their families to follow healthy behaviors that enhance health, optimize sleep, manage stress, and value of life. During COVID-19, present research explores the moderating role of SLP in the relationship among insomnia, psychological immunity, and psychological well-being. Survey research design and nonprobability purposive sampling technique were used. With APA ethical Consideration, online data was collected from 394 individuals from different cities of Pakistan. Results found that Synchronized Lifestyle Modification program has a significant negative relationship with insomnia but a significant positive relationship with psychological immunity and well-being. Results further found that insomnia has a negative relation with psychological immunity and well-being, this relationship will be weaker in case of a high Synchronized Lifestyle Modification program (SLP) practices.
TINDAK TUTUR PERSUASIF PEDAGANG KAKI LIMA DI PASAR KAGET GELORA HAJI AGUS SALIM PADANG
Authors: Kurniawan Ridho , Novita Yuliatri
Published: February 2021

Tujuan penelitian ini adalah untuk menemukan bentuk-bentuk serta fungsi-fungsi tindak tutur persuasif pedagang kaki lima di pasar kaget Gelora Haji Agus Salim. Berdasarkan hasil penelitian di 19 tempat yang berbeda, peneliti menemukan jumlah bentuk-bentuk tindak tutur persuasif pedagang sebanyak 39 data. Berdasarkan data tersebut, peneliti menemukan 3 bentuk tindak tutur persuasif yang terdiri dari 25 tindak tutur asertif, 13 tindak tutur direktif, dan 1 tindak tutur komisif. Selain itu, ada 6 jenis fungsi tindak tutur persuasif yang terdiri dari 18 fungsi bujukan, 11 fungsi anjuran, 7 fungsi ajakan, 1 fungsi persilahan, 1 fungsi himbauan, dan 1 fungsi permohonan. Bentuk tuturan persuasif yang paling banyak digunakan adalah asertif dan fungsi tuturan yang paling banyak digunakan adalah fungsi bujukan.
MENINGKATKAN KEMAMPUAN GURU DALAM MERENCANAKAN DAN MELAKSANAKAN PEMBELAJARAN MELALUI SUPERVISI AKADEMIK
Authors: Zulfia Ena
Published: February 2021

This aims study is to describe the implementations of both academic supervision and class observation  techniques to enhance of planning and performing learning skill of   Junior High School  6 Tanah Sepenggal Kabupaten Bungo teachers in academic year 2019/2020. This is an action research scool (PTS) study conducted by two cycles in with five person acted as the subject having been determinated based on the result of pracycles observation, observation techniques were  conducted to collect the data and quantitative descriptive analysis were used as data analysis.The study resulted that the implementation of  both academic supervision and class observation techniques enhanced the planning and performing  learning skill of Junior High School 6 Tanah Sepenggal Kabupaten Bungo teaches on odd semester in academic year 2019/2020.
MENINGKATKAN KOMPETENSI GURU DALAM MENYUSUN RPP BERORIENTASI PPK, GLN DAN HOTS MELALUI SUPERVISI
Authors: Hastutik Wiji
Published: February 2021

The problem of this research is the low ability of SMPN 3 Muko Muko Bathin VII teachers’ in arranging lesson plan which oriented to Character Education Strengthen, National Literation Movement and High Order Thinking Skill. This research is implemented to improve the teachers’ abillity in arranging the teaching preparation especially in arranging lesson plan which oriented to Character Education Strengthen, National Literation Movement and High Order Thinking Skill. I use supervision as the treatment. This research had two cycles. Each cycle included four phases. They are : planning, implementing, observing and reflecting. Data collection equipments are observation sheet, field note and questionnaire. Data analyzing is taken in each cycle to  know the influence of the treatment to improve the teachers’ ability and as the guidance in determining next planning. This research proved that the ability of SMPN 3 Muko Muko Bathin VII teachers in arranging lesson plan which oriented to Character Education Strengthen, National Literation Movement and High Order Thinking Skill increased well. The increasing of the teachers’ ability showed the advance from the first to the second cycle in arranging Character Education Strengthen learning is always consistent, the ability in designing National Literation Movement increase 18.2% and the aspect of High Order Thinking Skill increased 27,3%. While the implementation of teaching learning process, all teachers always consistent in building Character Education Strengthen, the implementation of National Literation Movement increased 18.2% and HOTS learning increased 9.1%. From the research, we can conclude that supervision is the appropriate treatment in advancing the teachers’ ability of SMPN 3 Muko Muko Bathin VII in designing lesson plan that oriented Character Education Strengthen, National Literation Movement and High Order Thinking Skill.
PENGARUH MODEL PEMBELAJARAN MIND MAPPING TERHADAP HASIL BELAJAR SISWA MATA PELAJARAN SEJARAH DI SMA NEGERI 8 PALEMBANG
Authors: Apriana Apriana Apriana , Mulyati Sri
Published: February 2021

Kenyataan di lapangan menunjukkan bahwa kebanyakan peserta didik sering kali merasa jenuh, malas, mengantuk, dan bosen terhadap pelajaran sejarah. Oleh sebab itu,penelitian ini bertujuan untuk mengetahui Pengaruh Model Pembelajaran Mind Mapping terhadap Hasil Belajar Siswa Mata Pelajaran Sejarah di SMA Negeri 8 Palembang”. Metode yang digunakan dalam penelitian ini yaitu penelitian kuantitatif. Berdasarkan hasil penelitian dan analisas data output “Test Statistic” diketahui Asymp.Sig. (2-tailed) bernilai 0,000. Karena nilai 0,000 < 0,05, maka dapat disimpulkan bahwa “Ha diterima”. Artinya ada perbedaan antara hasil belajar pretest dan posttest, sehingga dapat disimpulkan pula bahwa “Ada Pengaruh Model Pembelajaran Mind Mapping terhadap Hasil Belajar Siswa Mata Pelajaran Sejarah di SMA Negeri 8 Palembang”.
PENGARUH PERMAINAN KECIL 4 2 TERHADAP KETEPATAN PASSING TIM SEPAKBOLA SD NEGERI NO.166/II TIRTA MULYA
Authors: Baidi Baidi
Published: February 2021

Pada dasarnya, permainan sepakbola membutuhkan kerjasama tim dikarenakan masing-masing timnya terdapat 11 pemain. Sangat sulit sekali bekerja sama jika tidak adanya latihan koordinasi tim atau komunikasi antar pemain. penulis sengaja melakukan penelitian tersebut dengan tujuan mengurangi salah faham antar sesame pemain 1 tim pada saat bertanding dan dapat memperlihatkan permainan sepakbola yang indah. Jenis penelitian ini adalah oenelitian eksperimen karena adanya pre test, perlakuan, dan post test dengan melihat veriabel bebas dan variabel terikatnya.variabel bebas adalah Latihan Permainan Kecil 4 2 sedangkan variabel terikatnya adalah Ketepatan Passing. Populasi dalam penelitian ini adalah semua siswa kelas VI SD Negeri No.166/II Tirta Mulya. Hasil penelitiani ini menunjukkan variasi latihan passing dapat meningkatkan keterampilan passing dengan didukung hasil uji-t yaitu thitung = 5,8113 > ttabel = 1,725.
Minimal Agreement between Internal and External Training Load Metrics across a 2-wk Training Microcycle in Elite Squash
Authors: James Carl , Dhawan Aishwar , Jones Timothy , Pok Christopher , Yeo Vincent , Girard Olivier
Published: February 2021

This study investigated the relationships between internal and external training load metrics across a 2-week ‘in-season’ microcycle in squash. 134 on-court and 32 off-court ‘conditioning’ sessions were completed by fifteen elite squash players with an average (±SD) of 11 ± 3 per player. During every session, external load was captured using a tri-axial accelerometer to calculate Playerload; i.e., the instantaneous rate of change of acceleration across 3-dimensional planes. Internal load was measured using heart rate (HR), global (sRPE) and differential RPE (dRPE-Legs, dRPE-Breathing). Additionally, HR was used to calculate Banister’s, Edward’s and TEAM TRIMPs. Across 166 training sessions, Playerload was moderately correlated with TRIMP-Banister (r = 0.43 [95% CI: 0.29-0.55], p < 0.001) and TRIMP-Edwards (r = 0.50 [0.37-0.61], p < 0.001). Association of Playerload with TRIMP-TEAM (r = 0.24 [0.09-0.38], p = 0.001) was small. There was a moderate correlation between sRPE and Playerload (r = 0.46 [0.33-0.57], p < 0.001). Association of sRPE was large with TRIMP-Banister (r = 0.68 [0.59-0.76], p = 0.001), very large with TRIMP-Edwards (r = 0.79 [0.72-0.84], p < 0.001) and moderate with TRIMP-TEAM (r = 0.44 [0.31-0.56], p < 0.001). Both dRPE-Legs (r = 0.95 [0.93-0.96], p < 0.001) and dRPE-Breathing (r = 0.92 [0.89-0.94], p < 0.001) demonstrated nearly perfect correlations with sRPE and with each other (r = 0.91 [0.88-0.93], p < 0.001). Collection of both internal and external training load data is recommended to fully appreciate the physical demands of squash training. During a training microcycle containing a variety of training sessions, interpreting internal or external metrics in isolation may underestimate or overestimate the training stress a player is experiencing.
Reliability and Validity of the Polar V800 Sports Watch for Estimating Vertical Jump Height
Authors: Garnacho-Castaño Manuel V. , Faundez-Zanuy Marcos , Serra-Payá Noemí , Maté-Muñoz José L. , López-Xarbau Josep , Vila-Blanch Moisés
Published: February 2021

This study aimed to assess the reliability and validity of the Polar V800 to measure vertical jump height. Twenty-two physically active healthy men (age: 22.89 ± 4.23 years; body mass: 70.74 ± 8.04 kg; height: 1.74 ± 0.76 m) were recruited for the study. The reliability was evaluated by comparing measurements acquired by the Polar V800 in two identical testing sessions one week apart. Validity was assessed by comparing measurements simultaneously obtained using a force platform (gold standard), high-speed camera and the Polar V800 during squat jump (SJ) and countermovement jump (CMJ) tests. In the test-retest reliability, high intraclass correlation coefficients (ICCs) were observed (mean: 0.90, SJ and CMJ) in the Polar V800. There was no significant systematic bias ± random errors (p > 0.05) between test-retest. Low coefficients of variation (<5%) were detected in both jumps in the Polar V800. In the validity assessment, similar jump height was detected among devices (p > 0.05). There was almost perfect agreement between the Polar V800 compared to a force platform for the SJ and CMJ tests (Mean ICCs = 0.95; no systematic bias ± random errors in SJ mean: -0.38 ± 2.10 cm, p > 0.05). Mean ICC between the Polar V800 versus high-speed camera was 0.91 for the SJ and CMJ tests, however, a significant systematic bias ± random error (0.97 ± 2.60 cm; p = 0.01) was detected in CMJ test. The Polar V800 offers valid, compared to force platform, and reliable information about vertical jump height performance in physically active healthy young men.
Attacking Key Performance Indicators in Soccer: Current Practice and Perceptions from the Elite to Youth Academy Level
Authors: Herold Mat , Kempe Matthias , Bauer Pascal , Meyer Tim
Published: February 2021

Key Performance Indicators (KPIs) are used to evaluate the offensive success of a soccer team (e.g. penalty box entries) or player (e.g. pass completion rate). However, knowledge transfer from research to applied practice is understudied. The current study queried practitioners (n = 145, mean ± SD age: 36 ± 9 years) from 42 countries across different roles and levels of competition (National Team Federation to Youth Academy levels) on various forms of data collection, including an explicit assessment of twelve attacking KPIs. 64.3% of practitioners use data tools and applications weekly (predominately) to gather KPIs during matches. 83% of practitioners use event data compared to only 52% of practitioners using positional data, with a preference for shooting related KPIs. Differences in the use and value of metrics derived from positional tracking data (including Ball Possession Metrics) were evident between job role and level of competition. These findings demonstrate that practitioners implement KPIs and gather tactical information in a variety of ways with a preference for simpler metrics related to shots. The low perceived value of newer KPIs afforded by positional data could be explained by low buy-in, a lack of education across practitioners, or insufficient translation of findings by experts towards practice.
Maximal Fat Oxidation: Comparison between Treadmill, Elliptical and Rowing Exercises
Authors: Filipovic Michelle , Munten Stephanie , Herzig Karl-Heinz , Gagnon Dominique D.
Published: February 2021

Fat oxidation during exercise is associated with cardio-metabolic benefits, but the extent of which whole-body exercise modality elicits the greatest fat oxidation remains unclear. We investigated the effects of treadmill, elliptical and rowing exercise on fat oxidation in healthy individuals. Nine healthy males participated in three, peak oxygen consumption tests, on a treadmill, elliptical and rowing ergometer. Indirect calorimetry was used to assess maximal oxygen consumption (V̇O2peak), maximal fat oxidation (MFO) rates, and the exercise intensity MFO occurred (Fatmax). Mixed venous blood was collected to assess lactate and blood gases concentrations. While V̇O2peak was similar between exercise modalities, MFO rates were higher on the treadmill (mean ± SD; 0.61 ± 0.06 g·min-1) compared to both the elliptical (0.41 ± 0.08 g·min-1, p = 0.022) and the rower (0.40 ± 0.08 g·min-1, p = 0.017). Fatmax values were also significantly higher on the treadmill (56.0 ± 6.2 %V̇O2peak) compared to both the elliptical (36.8 ± 5.4 %V̇O2peak, p = 0.049) and rower (31.6 ± 5.0 %V̇O2peak, p = 0.021). Post-exercise blood lactate concentrations were also significantly lower following treadmill exercise (p = 0.021). Exercising on a treadmill maximizes fat oxidation to a greater extent than elliptical and rowing exercises, and remains an important exercise modality to improve fat oxidation, and consequently, cardio-metabolic health.
Head Cooling Prior to Exercise in the Heat Does Not Improve Cognitive Performance
Authors: Mazalan Nur Shakila , Landers Grant Justin , Wallman Karen Elizabeth , Ecker Ullrich
Published: February 2021

This study investigated the effectiveness of head cooling on cognitive performance after 30 min and 60 min of running in the heat. Ten moderately-trained, non-heat-acclimated, male endurance athletes (mean age: 22 ± 6.6 y; height: 1.78 ± 0.10 m; body-mass: 75.7 ± 15.6 kg; VO2peak: 51.6 ± 4.31 mL-1>kg-1>min) volunteered for this study. Participants performed two experimental trials: head cooling versus no-cooling (within-subjects factor with trial order randomized). For each trial, participants wore a head-cooling cap for 15 min with the cap either cooled to 0°C (HC) or not cooled (22°C; CON). Participants then completed 2 × 30 min running efforts on a treadmill at 70% VO2peak in hot conditions (35°C, 70% relative humidity), with a 10 min rest between efforts. Working memory was assessed using an operation span (OSPAN) task immediately prior to the 15 min cooling/no-cooling period (22°C, 35% RH) and again after 30 min and 60 min of running in the heat. Numerous physiological variables, including gastrointestinal core temperature (Tc) were assessed over the protocol. Scores for OSPAN were similar between trials, with no interaction effect or main effects for time and trial found (p = 0.58, p = 0.67, p = 0.54, respectively). Forehead temperature following precooling was lower in HC (32.4 ± 1.6°C) compared with CON (34.5 ± 1.1°C) (p = 0.01), however, no differences were seen in Tc, skin temperature, heart rate and ratings of perceived exertion between HC and CON trials at any time point assessed (p > 0.05). In conclusion, despite HC reducing forehead temperature prior to exercise, it did not significantly improve cognitive performance during (half-time break) or after subsequent exercise in hot environmental conditions, compared to a no cooling control.
Exploring Factors for English Language Learners’ Language Competence
Authors: Shi Hong
Published: February 2021

This study aims to analyze the relationships among self-efficacy, strategies, and goal orientations of college-level English Language Learners (ELLs). Participants who were more than 25 years old had a lower level of strategy use than those who were less than 25 years old. Greater strategy use could result in higher level of self-efficacy and goal orientations. When mastery goals increased, use of overall strategy, compensation, cognitive, metacognitive strategy and social strategy increased. Teachers are suggested to use scaffolding, set goals and adopt assessment methods to promote ELLs’ ability and mastery of class content instead of external evaluation to improve learners’ self-efficacy and confidence.
Socio-Psychological Alienation in Nathaniel Hawthorne’s “Young Goodman Brown”
Authors: Kharbutli Mahmoud , Al-Omoush Ishraq
Published: February 2021

This paper investigates socio-psychological alienation in Hawthorne’s story “Young Goodman Brown”. It focuses on Brown’s psychological motivations that lead him to leave his village, Salem, on a journey to be taken literally and allegorically along with the inner conflicts thereof. Eventually, the result is a short-lived schism in his psyche. In fact, what urges Brown to step farther into the dark wood is an insistence to discover the whole truth so as to put an end to any vacillation between threatening possibilities suggested by the devil about the Puritan society to which he belongs. Thus, Brown turns into a rejectionist of all the teachings of his Puritan culture. In the end not only does he liberate himself from these cultural shackles, but he also seems to rise above them. So, while he lives among his countrymen he is not one of them. Brown’s new psychological state never allows him to accept the evil nature and the hypocrisy of his ancestry. Moreover, the psychological confusion in Brown’s psyche reaches its peak in a state of depression that we notice at the end of the story, which eventually puts him among those who have come to be called the “dark” romantics of the period, along with Poe, Melville, and Dickinson.
The Effects of Applying the Problem-Based Learning (PBL) Theory on the 11th Grade Scientific Stream Students’ Acquisition of the Concepts of Physics and the Development of Their Critical Thinking Skills
Authors: Almasarweh Sami Salameh , Khudairat Mohammad
Published: February 2021

The current study explores the effects of applying the Problem-Based Learning (PBL) Strategy on the 11th-grade scientific stream Jordanian students' acquisition of the concepts of developing their critical thinking skills. This study's significance lies in its emphasis on the worldwide growing tendency to apply PBL teaching strategies that consider developing the students' mental capabilities and creative thinking skills and, consequently, help them solve status-de- facto educational problems face and solve problems in their lives. The researchers used the experimental method in their study, which is based on studying the relationship between the independent and the dependent variables. For this reason, three study student groups, equal in their age, intelligence, academic achievement, social and economic standing, were selected. Two experimental groups were exposed to the independent variable (PBL) method, whereas the third control group was not exposed to the independent variable. Instead, it was taught in the Motion Unit in Physics by using the traditional teaching method. The results of the study were analyzed statistically, applying for the SPSS program. The Arithmetic Mean, the Standard Deviation, the Torsional Modulus, and the T-Test were used for the study analysis. The study results revealed that the two (PBL) experimental groups have proved to be much more superior to the control group's third traditional teaching method.
THE EFFECTIVENESS OF EXECUTING
PROBATIONARY NON-CUSTODIAL PENALTIES
IN VARIOUS RISK GROUPS CONCERNING
THE RECIDIVISM OF PROBATIONERS
Authors: Węgliński Andrzej
Published: February 2021

Based on cross-sectional studies, this article evaluates the effectiveness of probation offi cers. The classifi cation of convicts into risk groups is intended to improve public security and adjust the type and intensity of treatment by probation offi cers to the profile of the probationers. In this way, it is possible to adjust the methodological measures used by probation offi cers to the work strategies of worldwide probation services based on the case management model. The effectiveness of supervision conducted by probation offi cers largely depends on their commitment to the resocialisation process and the way of treating probationers. The conclusions resulting from this text will be especially useful in the work of resocialisation offi cers and probation offi cers.
MANAGING THE PROBATION, WELFARE
AND GUARDIAN AD LITEM SERVICES TEAM.
MANAGERIAL COMPETENCE
Authors: Hein Katarzyna
Published: February 2021

The aim of the article is to present the aspects of managing the probation, welfare and guardian ad litem services team in the context of the managerial competence of the team manager. Based on a literature study, it has been emphasized that the level of managerial competence of a manager has a signifi cant impact on the eff ectiveness of team management. The first part of the article was devoted to the organization of the probation, welfare and guardian ad litem services team. Then, defi nition and functions of management were described. The tasks of the team manager are presented in reference to particular management functions. Afterwards, problematic aspects of managerial competences were presented. The key competences of a team manager were indicated, based on the managerial competence model developed by the Polish Agency for Enterprise Development. Also presented, was the impact of these competences on the eff ects of work. The summary highlighted the necessity of conducting empirical research, in order to explore the level of the team manager’s managerial competences as a determinant in the direction of changes and intensifi cation of training of managerial staff . It was also used as the basis for developing a model of the managerial competence of a person managing a team of probation officers. In the author’s opinion, managing the probation, welfare and guardian ad litem services team is an important aspect of the manager’s activity, and shaping professionalism in this fi eld becomes a serious challenge. Therefore, the team manager faces multi-dimensional requirements as the executor of the management process. They relate to qualifi cations in the area of knowledge, skills and experience, including managerial competences, as well as personality traits and ethical attitudes. By analysing the current state of knowledge in the field of managing the probation, welfare and guardian ad litem services team, one can get the impression that there are no publications that would develop this topic from the perspective of management science. Therefore, the article aims to partially fill the cognitive gap in this respect.
The effect of carrying a light shoulder bag and cross bag on trunk positioning in young adults
Authors: Fałatowicz Michał , Jankowicz-Szymańska Agnieszka , Kaczor Angelika
Published: February 2021

Introduction: Postural defects and accompanying dysfunctions are one of the greatest existing health problems. It is necessary to define factors responsible for the formation of incorrect body posture and strive to eliminate or modify them. The aim of the study was to determine changes in trunk positioning depending on the way of carrying a small handbag (the bag weighing 2.7 kg). Materials and methods: The study comprised 32 volunteers aged 21.75±2.00 years. The ZEBRIS Pointer system was used to test the body posture. The Statistica v13 program was applied for data compilation. Normality of distribution regarding variables was tested with the Shapiro-Wilk test. Differences between repeated measures were estimated using ANOVA, Friedman’s rank test and post hoc tests. The level of statistical significance was α=0.05. Results: Placing the bag on one shoulder significantly increased thoracic kyphosis, while wearing the bag diagonally across the trunk caused a significant increase in both thoracic kyphosis and lumbar lordosis. Other observed changes concerned the balance of the trunk in the sagittal plane, the position of the shoulder blades, symmetry of shoulder position and pelvic rotation. Conclusions: Carrying even a small load in the form of a bag significantly changes quality of body posture. Furthermore, changes in body posture depend on the way of carrying the load. Wearing the bag diagonally across the trunk is not better than carrying it asymmetrically on one shoulder.
The importance of ecologically oriented social work in solving social problems during the first wave of the COVID-19 pandemic
Authors: Jusko Peter
Published: February 2021

The base of this study is Critical Discurs Analysis which deals with argumentation strategies that were recorded in the media public debate in the period March–April 2020 in the Slovak Republic and discusses their connection with the application of eco-social approaches to solving social problems using the example of the SARS-CoV-2 pandemic. The main research question is: What are the eco-social topics linked to solving social problems during the coronavirus pandemic through ecologically oriented social work? On the basis of the presented results these topics are mainly the importance of man’s awareness about our dependence on the environment in which we live created by the topos of disadvantage, that shows short-term positive impact of the pandemic on the environment and it is expected that the situation after pandemic will deteriorate, the support of social cohesion and members of the society and the importance of reducing pressure from the social structures which causes self-exploitation of modern man.
Evaluating the effectiveness of a ‘Tobacco Monitor’ App in reporting violations of tobacco policy in the community
Authors:   Department of Public Health Dentistry, People’s College of Dental Sciences & Research Centre, Bhopal, Madhya Pradesh, Vini Mehta
Published: February 2021

It is of interest to evaluate the effectiveness of the “Tobacco Monitor” app in reporting violations of tobacco policy in the community. Hence, a study was conducted amongst the first and second-year undergraduate students of health science colleges of a University. Students were asked to register complaints related to tobacco violations on the tobacco monitor app. Registered complaints were verified by the National Forum for Tobacco Eradication (NFTE) and descriptive statistics were used in reporting the results. A total of 208 complaints on tobacco violation were registered through the Tobacco Monitor app, 163 valid complaints were identified and 45 reports were found invalid. 163 verified valid complaints by NFTE were transferred to the Non-Communicable Diseases (NCD) Cell, Maharashtra, India. It should be noted that anti-tobacco laws and national policies help to curb the menace of the tobacco epidemic to an extent. However, robust reporting and sustainable enforcement measures are required in implementing tobacco legislation effectively. We also report that youth are comfortable in using the Tobacco Monitor app for reporting violations on tobacco.
The 14‐3‐3 protein YWHAB inhibits glucagon‐induced hepatic gluconeogenesis through interacting with the glucagon receptor and FOXO1
Authors: Ji Linlin , Wang Qianqian , Liu Mengdan , Zhu Chaoyu , Xiao Yuanyuan , Han Junfeng , Fang Yunyun , Ye Jianping , Yin Jun , Wei Li
Published: February 2021

Glucagon antagonism has been reported as a new therapeutic approach to hyperglycaemia. As the 14‐3‐3 protein YWHAB has been identified as a regulator of the glucagon receptor (GCGR) by affinity purification and mass spectrometry, we examined the role of YWHAB in vivo. Ywhab knockout mice display impaired blood glucose homeostasis only under pyruvate stimulation. Deletion of Ywhab in mouse primary hepatocytes (MPHs) increases hepatocyte glucose production by magnifying the effect of glucagon. Mechanistic analysis indicates that YWHAB forms a phosphorylation‐dependent complex with GCGR and directly interacts with forkhead box O1 (FOXO1). Together, these results reveal the inhibitory role of YWHAB in glucagon‐mediated hepatic glucose production, which may be a potential target for the control of gluconeogenesis and associated metabolic diseases.
PARP1–RNA interaction analysis: PARP1 regulates the expression of extracellular matrix‐related genes in HK‐2 renal proximal tubular epithelial cells
Authors: Ke Jing , Liu Feng , Tu Yafang , Cai Zhitao , Luo Yu , Wu Xiongfei
Published: February 2021

Recent studies suggest that Poly(ADP‐ribose) polymerase 1 (PARP1) acts as an RNA‐binding protein in a majority of renal diseases with tubular cell injury. However, detailed knowledge of RNA targets and the RNA‐binding regions for PARP1 is unknown. Herein, mapping of iRIP‐seq reads in HK‐2 renal tubular epithelial cells showed a biased distribution at coding sequence (CDS) and intron regions that is specific to these cells. A total of 1708 differentially expressed genes were identified after PARP1 knockdown using RNA‐seq. Furthermore, transcriptome analysis also showed that selective variable splicing was globally regulated by PARP1 in HK‐2 cells. By comparison of PARP1 RNA‐seq and iRIP‐seq data, we found 68 overlapping genes that are enriched in ‘extracellular matrix’ pathway. Follow‐up identification of their interactions may contribute vital insights into the regulatory role of PARP1 as an RNA‐binding protein in HK‐2 cells.
Analyzing and predicting the LNM rate and prognosis of patients with intraductal papillary mucinous neoplasm of the pancreas
Authors: Tang Chao‐Tao , Liu Bi‐Xia , Chen Youxiang , Zeng Chunyan
Published: February 2021

Background

Current the surveillance and management are controversial for patients with IPMN. We aimed to develop an alternative nomogram to individualize IPMN prognosis and LNM.

Methods

Based on the data from SEER database of patients diagnosed with IPMN between 2004 and 2015, a nomogram predicting the survival and LNM of IPMN based on univariate and multivariate and Lasso regression analysis was performed, internally and externally validated, and measured by C‐index, and decision curve analysis (DCA), and compared to the 7th TNM stage.

Results

A total of 941 patients were included. Age, T stage examined nodes, tumor size, and pathology grade were identified as an independent factor for predicting LNM. The nomogram we established to predict LNM had a high predicting value with a C‐index value of 0.735 and an AUC value of 0.753. Interestingly, including T1 stage, we found an inverse correlation was between age and LNM. In addition, nomogram for predicting CSS also performed better than TNM stage both in the internal validation group (1‐year AUC:0.753 vs. 0.693, 3‐year AUC: 0.801 vs. 0.731, 5‐year AUC: 0.803 vs. 0.733) and external validation group (1‐year AUC: 0.761 vs. 0.701, 3‐year AUC: 0.772 vs. 0.713, 5‐year AUC:0.811 vs. 0.735). DCA analysis showed the nomogram showed a greater benefit across the period of follow‐up compared to 7th TNM stage.

Conclusion

A nomogram based on multivariate and Lasso regression analysis showed great clinical usability compared with current criteria. Also, for LNM of IPMN, younger age patients with IPMN should be attached more importance.
Rhodium(I)‐Catalyzed Enantioselective C(sp3)—H Functionalization viaCarbene‐Induced Asymmetric Intermolecular C—H Insertion†
Authors: Liu Bo , Xu Ming‐Hua
Published: February 2021

Main observation and conclusion

Transition‐metal‐catalyzed C—H insertion of metal‐carbene represents an excellent and powerful approach for C—H functionalization. However, despite remarkable advances in metal‐carbene chemistry, transition metal catalysts that are capable of enantioselective intermolecular carbene C—H insertion are mainly constrained to dirhodium(II) and iridium(III)‐based complexes. Herein, we disclose a new version of asymmetric carbene C—H insertion reaction with rhodium(I) catalyst. A highly enantioselective rhodium(I) complex‐catalyzed C(sp3)—H functionalization of 1,4‐cyclohexadienes with α‐aryl‐α‐diazoacetates was successfully developed. By using chiral bicyclo[2.2.2]‐octadiene as ligand, rhodium(I)‐carbene‐induced asymmetric intermolecular C—H insertion proceeds smoothly at room temperature, allowing access to a diverse variety of α‐aryl‐α‐cyclohexadienyl acetates and gem‐diaryl‐containing acetates in good yields with good to excellent enantioselectivities (up to 99% ee). Furthermore, the synthetic utility of the reaction was highlighted by facile synthesis of a novel cannabinoid CB1 receptor ligand. This method may offer a new opportunity for the development of therapeutically exploitable cannabinoid receptor type ligands in medicinal chemistry.
Can Hydrated Electrons be Produced from Water with Visible Light?
Authors: Pios Sebastian , Huang Xiang , Domcke Wolfgang
Published: February 2021

Ab initio computational methods are employed to explore whether hydrated electrons can be produced by the photodetachment of the excess hydrogen atom of the heptazinyl radical (HzH) in finite‐size HzH⋅⋅⋅(H2O)n clusters. The HzH radical is an intermediate species in the photocatalytic oxidation of water with the heptazine (Hz) chromophore. Hz (heptaazaphenalene) is the monomer of the ubiquitous polymeric water‐oxidation photocatalyst graphitic carbon nitride (g‐C3N4). The energy profiles of minimum‐energy excited‐state reaction paths for proton‐coupled electron transfer from HzH to water molecules were computed for the HzH⋅⋅⋅H2O and HzH⋅⋅⋅(H2O)4 complexes with the CASPT2 method. The results reveal that the photodetachment of the excess H‐atom from the HzH radical is a barrierless reaction in these hydrogen‐bonded complexes, resulting in the formation of H3O and H3O(H2O)3 radicals, respectively, which are finite‐size models of the hydrated electron. The computational results suggest that the photocatalytic formation of hydrated electrons from water with visible light could be possible in principle.
Next Generation Sequencing‐Based Identification of T‐Cell Receptors for Immunotherapy Against Hepatocellular Carcinoma
Authors: Ma Yipeng , Ou Jiayu , Lin Tong , Chen Lei , Chen Junhui , Wang Mingjun
Published: February 2021

Hepatitis B virus (HBV)‐related hepatocellular carcinoma (HCC) remains a global health concern, and HBV proteins may be ideal targets for T cell‐based immunotherapy for HCC. There is a need for fast and efficient identification of HBV‐specific T cell receptors (TCRs) for the development of TCR‐transduced T (TCR‐T) cell‐based immunotherapy. Two widely employed TCR identification approaches, T cell clonal expansion and single‐cell sequencing, involve a TCR singularization process for the direct identification of Vα and Vβ pairs of TCR chains. Clonal expansion of T cells is well known to have tedious time and effort requirements due to the use of T cell cultures, whereas single‐cell sequencing is limited by the requirements of cell sorting and the preparation of a single‐cell immune‐transcriptome library as well as the massive cost of the whole procedure. Here, we present a next‐generation sequencing (NGS)‐based HBV‐specific TCR identification that does not require the TCR singularization process. Conclusion: Two pairing strategies, ranking‐based strategy and α–β chain mixture‐based strategy, have proved to be useful for NGS‐based TCR identification, particularly for polyclonal T cells purified by a peptide‐major histocompatibility complex (pMHC) multimer‐based approach. Functional evaluation confirmed the specificity and avidity of two identified HBV‐specific TCRs, which may potentially be used to produce TCR‐T cells to treat patients with HBV‐related HCC.
Organophosphorus flame‐retardant tris(1‐chloro‐2‐propyl)phosphate is genotoxic and apoptotic inducer in human umbilical vein endothelial cells
Authors: Saquib Quaiser , Siddiqui Maqsood , Al‐Khedhairy Abdulaziz
Published: February 2021

Tris(1‐chloro‐2‐propyl)phosphate (TCPP) is a chlorinated organophosphorus flame retardant (OPFR) widely used in consumer goods after the phaseout of brominated flame retardants (BFRs). TCPP can percolate into the indoor and outdoor dusts, leading to its detection in the human body fluids (urine, breast milk) and placenta. However, TCPP has not been studied so far for its toxicity in the human vascular system. Hence, we have used human umbilical vein endothelial cells (HUVECs) and exposed them to TCPP ranging from low to high (5–400 μM) concentrations for 24 h. Cytotoxicity analysis by MTT and NRU assays exhibited 15.27% and 20.56%, 21.67%, and 48.67% survival decline of cells only at 200 and 400 μM. Comet assay data showed DNA damage from 50 to 400 μM with Olive tail moment (OTM) values between 1.03 and 35.59, respectively. TCPP‐exposed HUVECs exhibited 1.09 and 1.39‐fold greater intracellular reactive oxygen species (ROS) at 25 and 400 μM, indicating oxidative stress. HUVEC mitochondrial membrane potential (ΔΨm) measurements showed 1.16 and 1.48‐fold higher fluorescence of Rh123 dye at 25 and 400 μM, confirming mitochondrial dysfunction. Flow cytometric data demonstrated 5.1%–58.8% cells in SubG1 apoptotic phase at 5 and 400 μM TCPP. Our novel data revealed that TCPP is a genotoxic and apoptotic inducer, which may trigger alike responses in human vascular system. Overall, detailed in vivo studies are warranted on the transcriptional and translations effects of TCPP.
Effect of add‐on melatonin on seizure outcome, neuronal damage, oxidative stress, and quality of life in generalized epilepsy with generalized onset motor seizures in adults: A randomized controlled trial
Authors: Verma Nishant , Maiti Rituparna , Mishra Biswa Ranjan , Jha Menka , Jena Monalisa , Mishra Archana
Published: February 2021

Epilepsy treatment is challenging because of multiple impediments like lack of efficacy of monotherapy, adverse drug reactions, and different comorbidities. Add‐on therapy to first‐line antiepileptics may be the option to overcome therapeutic hurdles. The present randomized, double‐blind, add‐on placebo‐controlled clinical trial was conducted to evaluate the effect of add‐on melatonin in the treatment of generalized epilepsy with generalized onset motor seizure in adults. The control group (n = 52) received add‐on placebo, and the test group (n = 52) received add‐on melatonin (3 mg/day) with valproate (20 mg/kg in two divided doses). Clinical evaluation of seizure frequency, Chalfont‐National Hospital seizure severity scale (NHS3), Pittsburgh sleep quality index (PSQI), quality of life in epilepsy inventory, Epworth sleepiness scale (ESS), and biochemical estimation of serum neuron‐specific enolase (NSE) and glutathione reductase were done at baseline and compared with follow‐up at 8 weeks. Among 104 patients randomized [mean (SD) age of 27.6 (11.5); 84 (80.8%) male], 88 (84.6%) completed the trial. The responder rate and seizure‐free rate in the test group were significantly (p = 0.006 and 0.034) higher than the control group. There was a significantly higher reduction in the frequency of seizures (p = 0.016) and NHS3 (−2.39; 95%CI: −4.56 to −0.21; p = 0.032) in the test group compared to the control group. Similarly, improvement in PSQI (−1.40; 95%CI: −2.64 to −0.15; p = 0.029) was significantly better in the test group. There was no significant difference in the change in ESS (p = 0.621) and quality of life scoring (p = 0.456) between the study groups. The decrease in serum NSE was significantly higher with the test group compared to the control group (−2.01; 95% CI: −3.74 to −0.27; p = 0.024). Add‐on melatonin increased serum glutathione reductase significantly (p = 0.038), but there was no significant difference between the groups (p = 0.685). Add‐on melatonin with valproate for generalized epilepsy with generalized onset motor seizures in adults can achieve a significantly better clinical outcome by reducing the seizure frequency, severity and attaining a better seizure‐free rate in comparison to the control group.