bluuebunny/crossref_metadata_2025 huggingface dataset:
Supporting a lifetime of fitness for the military veteran athlete: a narrative review
Authors: Tinney Melissa J. , Nguyen Chantal
Published: December 2024

The military veteran starts their career at peak physical fitness. Once injured or retired, physical activity for the veteran is integral to rehabilitation, recovery, and ongoing wellness. This may require adaptation for continued participation in physical activity. The military veteran, in the United States, has access to resources which can facilitate ongoing physical activity, engagement in competitive and recreational sports, no matter what age or ability. Reviewing the current literature will help understand the scope of programs available, their outcomes, and strategies employed to support a lifetime of fitness that may be applied to other populations and health care systems.
A novel proceduralized donor liver back-table preparation technique minimizes hemorrhage following liver implantation in orthotropic liver transplantation
Authors: Tang Rui , Wu Guangdong , Tong Xuan , Yu Lihan , Li Ang , Lin Jingyi , Xu Guangxun , Lu Qian
Published: December 2024

Background

Intraoperative hemorrhage is one of the major complications of orthotopic liver transplantation (OLTX) and is mainly caused by technical difficulties of the surgical procedure besides primary liver diseases. The present study aimed to evaluate the feasibility and clinical effects of a novel proceduralized donor liver back-table preparation (DLBTP) technique for use in OLTX.

Methods

This retrospective study was conducted between January 2018 and June 2020 based on patients who had undergone OLTX. All livers transplanted using the reported back-table procedures were defined as the control group A (n = 43), while those prepared using our new procedure as the experimental group B (n = 160). The first-hand surgical experience of transplant surgeons was surveyed in a post hoc comparative analysis.

Results

DLBTP time was significantly longer and the probability of low-quality hepatic artery skeletonization was lower in group B compared to group A patients. Compared to group A, the time for hemorrhage control was shorter [P < 0.05, 0.3 h (range, 0.17–0.58 h)], and the degree of blood loss was less [P < 0.05, 60 ml (range, 30–240 ml)] in group B. Major bleeding sites were soft tissue of the hepatic hilum and the wall of the inferior vena cava. Due to trimmed soft tissue in the first porta hepatis region, there was less blood oozing, making it easier to stem the bleeding and construct anastomosis.

Conclusion

Although the procedural DLBTP for OLTX was time-consuming, the new procedure significantly reduced the degree of hemorrhage and the time required to control bleeding.
Analysis of the Effectiveness of Multifrequency OFDM Systems with a Constant Envelope in a Hydroacoustic Simulator and During In Situ Tests
Authors: Rodionov A. Yu. , Statsenko L. G. , Chusov A. A. , Kuzin D. A. , Smirnova M. M.
Published: December 2024

The key elements in the operation of modern underwater robotic systems are hydroacoustic communication and navigation systems. Hydroacoustic data transmission channels are designed in such a way that the transmitted information signals must be resistant to various types of interference and distortion, even without preliminary estimates of the channel parameters, due to their significant non-stationarity because of the roughness of the sea surface, currents, and the movement of underwater vehicles. Furthermore, due to the high mobility of underwater vehicles, the transmission time of navigation signals and necessary information packets must be significantly reduced, which can negatively affect the noise immunity of the packages. For these purposes, digital wideband signals and orthogonal frequency division multiplexing (OFDM) are widely used; however, a number of significant drawbacks of these types of modulations often do not allow for the forming of a reliable channel for transmitting information, and for the navigation of mobile underwater systems. Unfortunately, this problem is not comprehensively presented in the literature. The authors propose to use the algorithm of digital data transmission based on the OFDM constant envelope multifrequency modulation (CE-OFDM) with differential symbol coding, which is suitable for non-stationary hydroacoustic environments. The presented algorithm, due to the minimization of the signal peak factor, can improve the signal-to-noise ratio at the receiving end by 5–10 dB, with a number of other advantages, over the classical OFDM method. The authors also numerically found groups of short binary sequences from 14–55 elements long, with the best autocorrelation properties for the formation of synchronization and navigation preambles with high noise immunity to Doppler and multipath effects that are characteristic of the hydroacoustic communication channel. The proposed algorithms were tested on the certain channel models on the Watermark acoustic simulator, as well as in shallow water at distances up to 2 km.
Development and Experiment of an Air-Assisted Sprayer for Vineyard Pesticide Application
Authors: Ou Mingxiong , Zhang Yong , Wu Minmin , Wang Chenyang , Dai Shiqun , Wang Ming , Dong Xiang , Jiang Li
Published: December 2024

This paper presents an air-assisted sprayer for vineyard pesticide application. The spraying unit was designed with two symmetrically arranged ports. The airflow velocity distribution of the sprayer was investigated using a combination of experimental validation and a computational fluid dynamics (CFD) model. The results of both the simulation and the experiment showed good agreement in airflow velocity, and the distribution was uniform. Both unilateral and bilateral spraying field experiments were conducted in this study. The unilateral spraying experiment showed that higher spray pressure and lower sprayer speed increased both total deposition coverage and spray penetration (SP), while shorter spray distances improved SP but decreased total deposition coverage. The optimal operational conditions for the sprayer were determined as follows: spray pressure of 0.40 MPa, sprayer speed of 0.83 m/s, and spray distance of 1.00 m. The results of the bilateral spraying field experiment indicated that the coefficient of variation (CV) for deposition coverage in Columns A, B, and C were 16.20%, 8.10%, and 15.47%, respectively. The CVs in Layers a, b, and c were 6.14%, 12.62%, and 6.74%, respectively. This result demonstrated that the deposition coverage distribution in the canopy was relatively uniform, and the air-assisted sprayer exhibited good spray penetration performance. This study demonstrates the effectiveness and potential of the air-assisted sprayer for vineyard pesticide application.
Leaf Pruning End-Effector for Adaptive Positioning at the Branch–Stem Junction of Tomato Plants
Authors: Sun Yuhuan , Lu Wenqiao , Feng Qingchun , He Liang , Diao Hongda , Ma Yuhang , Chen Liping
Published: December 2024

To address the needs of mechanized tomato leaf pruning, this paper presents the design of an end-effector capable of adaptive positioning at the base of the branch. This design effectively prevents infection at the cut sites of a residual branch and protects the rest of the plant from damage. The design objectives for the pruning actuator were established through the measurement of key parameters related to the morphology and mechanical properties of the lateral branch. Based on this foundation, we developed an innovative gripper featuring a spiral guide groove, enabling simultaneous axial traction and radial cutting of the branch. This design ensures that the branch–stem junction conforms to the cutting blade under shear stress, achieving the required adaptive positioning. By analyzing the mechanical properties of the lateral branch, we modeled the actuator’s traction and cutting forces to determine the key geometric parameters of the spiral fingers and the necessary driving torque. We validated the actuator’s operational effectiveness through discrete element simulation and practical application tests. The experimental results indicate that when removing the branch, a traction force of 32.5 N and a cutting force of 66.3 N are generated. Harvesting effectiveness tests conducted in the tomato field achieved a success rate of 85%. This research offers technical support for the development of handheld pruning devices and pruning robots.
The Participation of Trehalose Metabolism in Response to High-Humidity Stress in Megoura crassicauda (Hemiptera: Aphididae)
Authors: Ma Wu , Si Huiru , Wan Sijing , Zhan Qinwen , He Yanlan , Zhou Wenjing , Wen Weiwei , Xie Yuhang , Tan Xiaoling , Sun Sisi , Tang Bin
Published: December 2024

In the context of climate change, characterized by an increase in average precipitation, agricultural pests have demonstrated enhanced adaptability to high humidity and other challenging environmental conditions, thereby intensifying the need for effective prevention and control measures. Among these pests, Megoura crassicauda (Hemiptera: Aphididae) represents a significant threat to both crop yield and quality. The aim of this study was to investigate the physiological behavioral changes and the regulatory mechanisms of trehalose metabolism in M. crassicauda under conditions of high-humidity stress. Additionally, we sought to explore the survival strategies and water regulation mechanisms employed by this insect, with the goal of identifying new biological targets for its management. The findings indicated that, despite an increase in environmental humidity, there was no significant difference in the survival rate of M. crassicauda. However, a reduction in developmental duration and reproductive capacity was observed. Increased humidity correlated with elevated trehalose levels and decreased glycogen content. Notably, although the relative expression levels of trehalase (TRE) and Trehalose-6-phosphate synthase (TPS) were downregulated, Trehalose-6-phosphate phosphatase (TPP) expression was upregulated. These results suggest that high humidity environments significantly influence the growth, development, and trehalose metabolism of M. crassicauda. It appears that adaptations to high-humidity conditions in M. crassicauda are facilitated by modulations in the types and distribution of sugars within their bodies, achieved through alterations in the expression of genes associated with trehalose metabolism. In summary, the results of this study indicate that high humidity significantly affects the development and sugar metabolism of M. crassicauda. These changes may represent one of the potential mechanisms underlying its environmental adaptation and migration. This insight provides valuable assistance for predicting the occurrence and migration of the pest M. crassicauda.
Sowing Rates and Methods Affect Yield and Forage Quality of American Jointvetch in the Southwestern Area of Japan
Authors: Tobisa Manabu , Nakano Yutaka
Published: December 2024

This research aimed to assess how different sowing methods and seeding rates influenced the growth, yield characteristics, and forage nutritional value for establishing American jointvetch, a tropical forage legume known for its high productivity and quality, in grasslands in southwestern Japan. The experimental treatments involved two sowing methods, row sowing (RS) and broadcast sowing (BS), and combinations of four different seeding rates (SR, 5, 10, 20, or 30 kg ha−1). The sowing methods affected dry matter yield (DMY): BS resulted in higher DMY (11.3 vs. 8.7 t DM ha−1) and leaf area index (LAI, 7.2 vs. 5.3) than RS, respectively. However, in vitro dry matter digestibility (IVDMD) and crude protein (CP) concentrations were not influenced by the sowing methods. The SR affected LAI, particularly RS, and LAI increased with increasing SR. Contrary to expectations, SR did not affect DMY, IVDMD, CP, digestible DMY, or CP yield. The findings of this investigation indicate that broadcast sowing is the superior method for planting, and even when using a reduced seeding rate of 5 kg ha−1 of seed-in-pod, there was no significant impact on the yield or forage quality of American jointvetch under the conditions examined in this study. This information will contribute to the proper management of its cultivation to ensure higher productivity for use as livestock fodder.
Natural Variation in the AAT1 Promoter Is Responsible for the Disparity in Ester Aroma Between Actinidia chinensis and Actinidia eriantha
Authors: Cao Qing , Huang Zhenyu , Chen Jinyin , Gan Zengyu
Published: December 2024

To understand ester compound biosynthesis in kiwifruit, two Actinidia species with distinct characteristics were compared. The firmness of Donghong (Actinidia chinensis) and Ganlv-1 (Actinidia eriantha) fruits gradually decreased as the fruit ripened after harvest, whereas the total soluble solids increased continuously, reaching a peak on the 8th day. The Ganlv-1 fruit ester content was significantly lower than in the Donghong fruits at the optimal eating stage, and the alcohol acyltransferase (AAT) activity in the Ganlv-1 fruits was significantly lower than in the Donghong fruits. The gene expression levels of AAT1 and AAT17 in the Donghong fruits were significantly higher than in the Ganlv-1 fruits, with a particularly remarkable difference observed for AAT1, which exhibited a 36-fold higher expression in the Donghong fruits when compared with the fully ripened Ganlv-1 fruits. A transient overexpression of the AAT1 gene in the kiwifruit led to a significant increase in ester content. Interestingly, a natural variation was observed in the promoter sequence of AAT1 between the Donghong and Ganlv-1 cultivars. Furthermore, separate analyses of the respective promoter activities revealed significantly higher activity levels in the Donghong fruits than in the Ganlv-1 fruits. In conclusion, a natural variation in the AAT1 promoter is primarily responsible for the disparity in AAT1 gene expression between the Donghong and Ganlv-1 fruits, resulting in a divergent accumulation of ester aroma compounds during the postharvest ripening stages.
Genomic Analysis of Sarda Sheep Raised at Diverse Temperatures Highlights Several Genes Involved in Adaptations to the Environment and Heat Stress Response
Authors: Gaspa Giustino , Cesarani Alberto , Pauciullo Alfredo , Peana Ilaria , Macciotta Nicolò P. P.
Published: December 2024

Livestock expresses complex traits influenced by several factors. The response of animals to variations in climatic factors, such as increases in temperature, may induce heat stress conditions. In this study, animals living at different temperatures were compared using the genome-wide Wright fixation index (FST). A total of 825 genotypes of Sarda breed ewes were divided into two groups based on the flocks’ average temperature over a 20-year period to compute the FST: 395 and 430 sheep were represented in colder and hotter groups, respectively. After LOWESS regression and CONTROL CHART application, 623 significant markers and 97 selection signatures were found. A total of 280 positional candidate genes were retrieved from a public database. Among these genomic regions, we found 51 annotated genes previously associated with heat stress/tolerance in ruminants (FCGR1A, MDH1, UGP2, MYO1G, and HSPB3), as well as immune response and cellular mechanisms related to how animals cope with thermal stress (RIPK1, SERPINB1, SERPINB9, and PELI1). Moreover, other genes were associated with milk fat (SCD, HERC3, SCFD2, and CHUK), body weight, body fat, and intramuscular fat composition (AGPAT2, ABCD2, MFAP32, YTHDC1, SIRT3, SCD, and RNF121), which might suggest the influence of environmental conditions on the genome of Sarda sheep.
DNA Barcoding Reveals Species Diversity and Host Associations of Dryinidae Wasps (Insecta, Hymenoptera): A Case Study from the Xisha Islands in the South China Sea
Authors: Chen Huayan , Olmi Massimo , Wang Jun , Sun Qilin , Luo Shixiao
Published: December 2024

Dryinidae is a cosmopolitan wasp family, with over 1900 species found worldwide [...]
Expression of αv Integrin in Feline Injection-Site Sarcoma (FISS): Preliminary Investigations
Authors: Cappelleri Andrea , Brambilla Eleonora , Chiti Lavinia E. , Trapletti Alessia , Bianchi Gaia B. M. , Di Giancamillo Mauro , Grieco Valeria , Giudice Chiara
Published: December 2024

Feline injection-site sarcomas (FISSs) are malignant skin tumors of mesenchymal origin arising at local post-vaccination (or injection) sites. In recent years, a fluorescence imaging technique based on probes targeting αvβ3 integrin has been effectively applied for the surgical complete resection of the tumor. In our study, we investigated the utility of a commercially available anti-αv integrin polyclonal antibody for the histopathological evaluation of FISS’s surgical excision margins. We collected 10 formalin-fixed paraffin-embedded (FFPE) feline excisional biopsies with a histopathological diagnosis of FISS (7 fibrosarcomas and 3 pleomorphic sarcomas) and wide margin tissue, along with one subcutaneous injection-site granuloma and 6 osteosarcomas. Samples were processed for histology, and slides were stained for IHC with the anti-αv integrin antibody. Immunostained slides were evaluated for the cellular localization and intensity of the staining in different neoplastic and non-neoplastic cell populations. Neoplastic and non-neoplastic spindle cells had cytoplasmic positivity in all fibrosarcomas. Inflammatory cells, including macrophages of the injection-site granuloma, were negative. Multinucleated giant cells in the pleomorphic sarcomas had an intense membranous positivity. Although the anti-αv integrin antibody was ineffective for the histopathological evaluation of surgical excision margins, the membranous localization of αv integrin in multinucleated giant cells of pleomorphic sarcomas suggests that it plays a role in the oncogenesis of this FISS variant.
Influence of Dietary Cobalt on Fiber Digestibility and Serum Cobalt and Cobalamin Concentrations in Horses
Authors: LeCompte Lazić Rebecca Ashlee , Nielsen Brian D. , Robison Cara I. , Schott Harold C. , Herdt Thomas H. , Larson Connie K.
Published: December 2024

The 2007 Horse NRC reduced cobalt (Co) requirements from 0.1 ppm to 0.05 ppm in dietary dry matter, though preliminary research suggested increasing dietary-Co enhanced fiber digestion in horses. This study aimed to evaluate fiber digestion with varying dietary Co amounts, as well as to compare serum Co concentrations with dietary Co content. Four geldings (mean body weight [BW] 503 ± 37 kg) were studied in a 4 × 4 Latin square design consisting of four 5-week periods, each comprising a 2-week washout phase followed by a 3-week treatment phase. Supplementing 0.0, 5.6, 16.8, or 28.0 mg of Co daily resulted in total Co dietary concentrations of 0.06, 0.7, 2.0, and 3.0 ppm, respectively. Feces and urine were collected to evaluate fiber digestibility and Co balance. Co supplementation did not affect neutral detergent fiber, acid detergent fiber, or lignin digestibility. Co balance was negative for the control diet but positive for the other three treatments (p = 0.04). Serum cobalamin concentrations slightly decreased (6%) with increasing dietary Co intake (p = 0.003), while folate concentrations were unaffected. Serum Co concentration differed (p < 0.01) with a mean of 4.7 μg/mL for the high treatment and 0.8 μg/mL for the control. Results suggest that serum Co concentrations above regulatory limits are likely due not to higher levels of Co in fortified feeds, but rather to parenteral administration of Co solutions.
Impacts of Black Soldier Fly (Hermetia illucens) Larval Meal on Intestinal Histopathology and Microbiome Responses in Hybrid Grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂): A Comprehensive Analysis
Authors: Chen Yan , Ma Jun , Yong Yoong-Soon , Chen Yonggan , Chen Bing , Cao Junming , Peng Kai , Wang Guaxia , Huang Hai , Loh Jiun-Yan
Published: December 2024

This study examined the diversity and responses of intestinal microbiota in hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂) fed diets with varying levels of fishmeal replaced by black soldier fly larvae (BSFL). The 10% BSFL substitution (BSFL10) group showed the highest levels of trypsin and amylase. Substituting fishmeal with 30% and 50% BSFL weakened the intestinal wall, resulting in vacuoles, sparse striatal boundaries, and fewer villi. Microbiota diversity, measured through Shannon’s index, was higher in the BSFL10 and BSFL50 groups than in the control. 16S rRNA amplicon data revealed the dominance of Firmicutes, Proteobacteria, Bacteroidetes, Spirochaetota, and Verrucomicrobia phyla. The BSFL-replacement groups showed an increase in Proteobacteria, Bacteroidetes, and Spirochaetota compared to the control, but fewer Firmicutes. PICRUSt analysis indicated significant alterations in microbial function, particularly enhanced protein, carbohydrate, lipid, and energy metabolisms in the BSFL-fed group. Substituting 10% fishmeal with BSFL enhanced nutrient metabolism and gut microbiota in juvenile hybrid grouper. Further research is needed to explore factors affecting the efficacy of insect feed as a sustainable aquaculture diet.
Multiple Typing Approach to Characterize Toxoplasma gondii Strains from Captive and Livestock Species in Northern Italy Suggests the Circulation of Type-II Variants
Authors: Dini Filippo Maria , Salas-Fajardo Martha Ynés , Taddei Roberta , Ramini Mattia , Vianello Silvia , Caffara Monica , Galuppi Roberta
Published: December 2024

Toxoplasma gondii is a widespread foodborne parasite that affects both humans and animals worldwide. The genetic characterization of this parasite has become crucial due to its epidemiological and clinical implications. The present study focused on the direct genetic characterization of T. gondii-positive DNA samples from Northern Italy, using three standardized genotyping methods. Of the 87 PCR-positive DNA samples obtained from livestock, wild, and captive animals, 9 were confirmed, quantified, and subsequently subjected to typing procedures: microsatellite analysis, PCR-RFLP, and partial sequencing of GRA6 and SAG3 genes. Most of the typed samples, derived from clinical cases of toxoplasmosis, specifically related to abortion outbreaks in small ruminants, as well as one case of systemic toxoplasmosis in lemur (Lemur catta). Predominantly, Type II strains were observed, with non-clonal variants identified in a sheep and a lemur. Sequencing of SAG3 revealed specific single nucleotide polymorphism, previously documented in European type-II variants, with phylogenesis suggesting a potential genetic relatedness between T. gondii population in Italy, Spain, and France. By utilizing three distinct genotyping methods, this study provides the first comprehensive microsatellite profiles of T. gondii in Italy, and additional insights into the molecular variability of T. gondii strains circulating in this country from different epidemiological settings.
Lipid Nanovesicles for Antioxidant Delivery in Skin: Liposomes, Ufasomes, Ethosomes, and Niosomes
Authors: Ricci Agnese , Stefanuto Luca , Gasperi Tecla , Bruni Fabio , Tofani Daniela
Published: December 2024

The skin, being the largest organ of the human body, serves as the primary barrier against external insults, including UV radiation, pollutants, and microbial pathogens. However, prolonged exposure to these environmental stressors can lead to the generation of reactive oxygen species (ROS), causing oxidative stress, inflammation, and ultimately, skin aging and diseases. Antioxidants play a crucial role in neutralizing ROS and preserving skin health by preventing oxidative damage. In recent years, nanotechnology has emerged as a powerful tool for enhancing the delivery of antioxidants onto the skin. In particular, liposomal formulations have offered unique advantages such as improved stability, controlled release, and enhanced penetration through the skin barrier. This has led to a surge in research focused on developing liposomal-based antioxidant delivery systems tailored for skin health applications. Through a comprehensive analysis of the literature from the 2019–2024 period, this review provides an overview of emerging trends in the use of liposomal delivery systems developed for antioxidants aimed at improving skin health. It explores the latest advancements in liposomal formulation strategies, vesicle characterization, and their applications in delivering antioxidants to combat oxidative stress-induced skin damage and other associated skin pathologies. A comparison of various delivery systems is conducted for the most common antioxidants. Finally, a brief analysis of lipid nanovesicles used in the cosmeceutical industry is provided.
Antibodies Against Anti-Oxidant Enzymes in Autoimmune Glomerulonephritis and in Antibody-Mediated Graft Rejection
Authors: Bruschi Maurizio , Candiano Giovanni , Petretto Andrea , Angeletti Andrea , Meroni Pier Luigi , Prunotto Marco , Ghiggeri Gian Marco
Published: December 2024

Historically, oxidants have been considered mechanisms of glomerulonephritis, but a direct cause–effect correlation has never been demonstrated. Several findings in the experimental model of autoimmune conditions with renal manifestations point to the up-regulation of an oxidant/anti-oxidant system after the initial deposition of autoantibodies in glomeruli. Traces of oxidants in glomeruli cannot be directly measured for their rapid metabolism, while indirect proof of their implications is derived from the observation that Superoxide Oxidase 2 (SOD2) is generated by podocytes after autoimmune stress. The up-regulation of other anti-oxidant systems takes place as well. Here, we discuss the concept that a second wave of antibodies targeting SOD2 is generated in autoimmune glomerulonephritis and may negatively influence the clinical outcome. Circulating and renal deposits of anti-SOD2 antibodies have been detected in patients with membranous nephropathy and lupus nephritis, two main examples of autoimmune disease of the kidney, which correlate with the clinical outcome. The presence of anti-SOD2 antibodies in circulation and in the kidney has been interpreted as a mechanism which modifies the normal tissue response to oxidative stress. Overall, these findings repropose the role of the oxidant/anti-oxidant balance in autoimmune glomerulonephritis. The same conclusion on the oxidant/anti-oxidant balance may be proposed in renal transplant. Patients receiving a renal graft may develop antibodies specific for Glutathione Synthetase (GST), which modulates the amount of GST disposable for rapid scavenging of reactive oxygen species (ROS). The presence of anti-GST antibodies in serum is a major cause of rejection. The perspective is to utilize molecules with known anti-oxidant effects to modulate the anti-oxidative response in autoimmune pathology of the kidney. A lot of molecules with known anti-oxidant effects can be utilized, many of which have already been proven effective in animal models of autoimmune glomerulonephritis. Many molecules with anti-oxidant activity are natural products; in some cases, they are constituents of diets. Owing to the simplicity of these drugs and the absence of important adverse effects, many anti-oxidants could be directly utilized in human beings.
Chilean Papaya (Vasconcellea pubescens): A Native Fruit with a High Health-Promoting Functional Potential
Authors: Lemus-Mondaca Roberto , Puente-Díaz Luis , Cifuentes Angélica , Lizama Katherine , González Paula
Published: December 2024

Papaya fruit is commonly known for its nutritional and medicinal value. It is a perennial, herbaceous, and trioecious cross-pollinated species with male, female, and hermaphrodite plants. The Chilean papaya, originating from South America, has been extensively spread throughout the Andean nations, cultivated primarily in the Coquimbo and Valparaíso valleys in Chile, between 34°41′ and 36°33′ latitude south. Its intense aroma, yellow color, and oblong shape characterize this fruit. It also stands out for its high content of carotenoids, vitamins, proteins, and polysaccharides, which make it a great functional food. Also, papaya contains bioactive compounds with antifungal, anti-inflammatory, and wound-healing effects. For years, the fruit has been used to produce canned fruit, juice, and candies to satisfy the local market. Chilean papaya has significant economic importance, supplying both local and international markets. This review aims to consolidate the evidence-based information on the native Chilean papaya (Vasconcellea pubescens) as a food matrix. The fruit’s ripening process, nutritional composition, industrial applications, and health-promoting properties, including its antioxidant and antidiabetic effects, are thoroughly examined. Additionally, the extraction of papaya oil, encapsulation of bioactive compounds, industrial and artisanal processing techniques, and patents are explored, highlighting the diverse applications and potential benefits of this fruit.
Freeze–Thaw Damage Characteristics of Soil–Rock Mixtures in Open-Pit Coal Mines and Stability Analysis of Slopes in Discharge Sites Based on Partial Flow Code
Authors: Li Rui , Guo Yihan , Zhou Wei , Lu Xiang , Zhang Zhiyuan , Tian Ya , Qi Xiang
Published: December 2024

More than 80% of open-pit coal mines in China are located in northern regions, and the mechanical properties and stability of loose soil–rock mixtures in waste disposal sites are significantly affected by freeze–thaw effects. This article takes the external dumping site of the Baorixile open-pit coal mine in the northern high-altitude region of the Inner Mongolia Autonomous Region as the research object. Through on-site investigation and sampling, indoor triaxial tests (confining pressures of 100 KPa, 200 KPa, and 300 Kpa; moisture contents of 18%, 21%, and 24%), numerical simulation, and other methods, the mechanical properties of soil–rock mixtures in the dumping site under different freeze–thaw cycle conditions were tested to reveal the specific influence of the number of freeze–thaw cycles on the mechanical properties of soil–rock mixtures. Using the discrete element software PFC, the microstructural changes in soil–rock mixtures formed by freeze–thaw cycles were studied, and the deformation mechanism and slip mode of loose slopes in waste disposal sites under different freeze–thaw cycle conditions were explored. The relationship between the number of freeze–thaw cycles and slope stability was clarified. The following conclusions can be drawn: the compressive strength of soil–rock mixtures decreases as a quadratic function with increasing freeze–thaw cycles; as the number of freeze–thaw cycles increases, the internal cracks of the soil–rock mixture model increase exponentially; and as the number of freeze–thaw cycles increases, the stability of the slope in the dumping site decreases significantly, and this stability also decreases with an increase in dumping height.
Forward Computational Modeling of Respiratory Airflow
Authors: Akor Emmanuel A. , Han Bing , Cai Mingchao , Lin Ching-Long , Kaczka David W.
Published: December 2024

The simulation of gas flow in the bronchial tree using computational fluid dynamics (CFD) has become a useful tool for the analysis of gas flow mechanics, structural deformation, ventilation, and particle deposition for drug delivery during spontaneous and assisted breathing. CFD allows for new hypotheses to be tested in silico, and detailed results generated without performing expensive experimental procedures that could be potentially harmful to patients. Such computational techniques are also useful for analyzing structure–function relationships in healthy and diseased lungs, assessing regional ventilation at various time points over the course of clinical treatment, or elucidating the changes in airflow patterns over the life span. CFD has also allowed for the development and use of image-based (i.e., patient-specific) models of three-dimensional (3D) airway trees with realistic boundary conditions to achieve more meaningful and personalized data that may be useful for planning effective treatment protocols. This focused review will present a summary of the techniques used in generating realistic 3D airway tree models, the limitations of such models, and the methodologies used for CFD airflow simulation. We will discuss mathematical and image-based geometric models, as well as the various boundary conditions that may be imposed on these geometric models. The results from simulations utilizing mathematical and image-based geometric models of the airway tree will also be discussed in terms of similarities to actual gas flow in the human lung.
A Learning Emotion Recognition Model Based on Feature Fusion of Photoplethysmography and Video Signal
Authors: Zhu Xiaoliang , He Zili , Wang Chuanyong , Dai Zhicheng , Zhao Liang
Published: December 2024

The ability to recognize learning emotions facilitates the timely detection of students’ difficulties during the learning process, supports teachers in modifying instructional strategies, and allows for personalized student assistance. The detection of learning emotions through the capture of convenient, non-intrusive signals such as photoplethysmography (PPG) and video offers good practicality; however, it presents new challenges. Firstly, PPG-based emotion recognition is susceptible to external factors like movement and lighting conditions, leading to signal quality degradation and recognition accuracy issues. Secondly, video-based emotion recognition algorithms may witness a reduction in accuracy within spontaneous scenes due to variations, occlusions, and uneven lighting conditions, etc. Therefore, on the one hand, it is necessary to improve the performance of the two recognition methods mentioned above; on the other hand, using the complementary advantages of the two methods through multimodal fusion needs to be considered. To address these concerns, our work mainly includes the following: (i) the development of a temporal convolutional network model incorporating channel attention to overcome PPG-based emotion recognition challenges; (ii) the introduction of a network model that integrates multi-scale spatiotemporal features to address the challenges of emotion recognition in spontaneous environmental videos; (iii) an exploration of a dual-mode fusion approach, along with an improvement of the model-level fusion scheme within a parallel connection attention aggregation network. Experimental comparisons demonstrate the efficacy of the proposed methods, particularly the bimodal fusion, which substantially enhances the accuracy of learning emotion recognition, reaching 95.75%.
Delayed-Expansion Capsule Sealing Material for Coal Mine Overburden Isolated Grouting
Authors: Xuan Dayang , Ning Xiaoming , Lu Kaifang , Li Jian , Xu Jialin
Published: December 2024

Grouting technology is an important method of ground reinforcement and can effectively improve the stability of engineering rock mass. During overburden isolated grouting in coal mines, the influence of unexpected fractures may lead to substantial grout leakage, resulting in ineffective grouting. The existing natural sedimentation sealing method is mainly applicable to small fractures and low grout flow, while the chemical-reagent rapid-sealing method can cause grouting channel blocking, making it less suitable for overburden isolated grouting. This paper proposes a “capsule” sealing method, detailing the preparation of the sealing material and evaluation of its properties through testing. The sealing material, prepared using the air suspension method, was coated with paraffin on a superabsorbent polymer (SAP) material, which has delayed expansion characteristics. Although this material does not expand within the grouting fractures of overburden rock, it expands rapidly upon entering the leakage channel, accumulating within the channel to achieve effective sealing. A simulation experimental system was designed to simulate the sealing of the slurry leakage channel, and the sealing characteristics were experimentally investigated. Under consistent particle size conditions, a higher film cover ratio led to a more pronounced delayed expansion effect and extended the time required for the sealing material to achieve its maximum expansion. When the content of sealing material with particle sizes of 20 mesh, 40 mesh, and 60 mesh, and a film ratio of 20% was 1.0%, the fractures below 4 mm were effectively sealed. When the fracture aperture is 4–6 mm, the sealing material with a covering ratio of 20% or 30% should have a minimum content of 1.5%, while the sealing material with a covering ratio of 50% should have a minimum content of 2.0%. The findings of this study outline an effective prevention and control method for the sealing of abnormal slurry leakage in overburden isolated grouting engineering.
Imaging and Optical Emission Spectroscopy of Surface Dielectric Barrier Discharge (SDBD) Plasma Generated Using Reactors with Planar and Cylindrical Electrodes
Authors: Tański Mateusz , Podliński Janusz , Berendt Artur , Mizeraczyk Jerzy
Published: December 2024

We characterized non-thermal plasma generated in two types of Surface Dielectric Barrier Discharge (SDBD) reactors, one with a planar and the other with a cylindrical electrode. Plasma was examined using the time-resolved imaging and Optical Emission Spectroscopy (OES) methods. We observed that the cylindrical electrode suppresses plasma formation during both discharge modes: positive streamers and pseudo-Trichel microdischarges. The propagation velocity of the plasma front was estimated to be in the range 12–15 m/s, regardless of the discharge mode and electrode type. Spectral analysis showed that the plasma emission spectrum consisted mainly of the first and second positive nitrogen bands. Using Specair software, we calculated the plasma thermodynamic parameters and found that, despite morphological differences, the plasma generated in both reactors had similar thermodynamic properties. Finally, we discussed the temporal evolution of the discharge and attributed the plasma suppression caused by the cylindrical electrode to the characteristic uniformity of the electric field around and along this electrode.
Numerical Investigation of Multi-Stage Radial Turbine Performance Under Variable Waste Heat Conditions for ORC Systems
Authors: Witanowski Łukasz
Published: December 2024

This study investigates the performance of a centrifugal radial turbine within an Organic Rankine Cycle (ORC) system, focusing on operation beyond the design point due to variable waste heat sources. With the goal of integrating the turbine into optimal ORC operating conditions, its performance was analyzed using R245fa as the working fluid over three stages with varying numbers of blades. A detailed computational analysis was performed using Ansys CFX software (Version 2020 R2) with the k-ω SST turbulence model using thermodynamic data from the NIST Refprop database. The results showed significant discrepancies when operating beyond the design point. At an inlet pressure of 780 kPa, the turbine internal power was calculated to be 120 kW—double the manufacturer’s maximum of 60 kW—and the mass flow rate exceeded 6 kg/s compared to the design value of 2.72 kg/s. These results highlight the challenges of adapting the turbine to fluctuating waste heat conditions, as factors such as tip clearance, blade geometry, and high outlet pressure have a significant impact on efficiency and system performance.
Digital Transformation in the Chemical Industry: The Potential of Augmented Reality and Digital Twin
Authors: Moreira Lorena Claudia de Souza , Rebello Carine Menezes , Costa Erbet Almeida , Sánchez Antonio Santos , Ribeiro Lucília S. , Nogueira Idelfonso B. R.
Published: December 2024

In the era of Industry 4.0 and industrial digitization, augmented reality (AR) is a powerful technology with the potential to revolutionize numerous sectors. However, despite a proliferation of supporting tools and hardware and demonstrated benefits in effectiveness, intuitiveness, and ease of use, the practical implementation of AR within the chemical industries remains surprisingly limited. This indicates a potential shortfall in research and development initiatives aimed at fully exploiting the capabilities of AR for industrial applications. This manuscript presents a comprehensive review of the existing landscape of AR within the industry, aiming to shed light on this intriguing paradox. After providing an extensive overview of the current state of AR in industry, we propose a schematic guideline as a systematic approach for introducing AR into industrial operations. The objective of this guide is to bridge the gap between AR’s evident potential and its actual application, fostering a broader adoption of this innovative technology in the industrial sector. Our work offers valuable insights and a practical roadmap for stakeholders aiming to leverage the transformative power of AR in industrial activities.
A Fuzzy-Control Anti-Cybersickness Intelligent System (FCACIS) Designed for Multiple Inducing Factors in a 3D Virtual Store
Authors: Liu Cheng-Li , Uang Shiaw-Tsyr
Published: December 2024

As online shopping has increased, the business models of online stores have diversified. When consumers cannot experience an actual product, merchants will promote products through a display to attract customers. Virtual reality (VR) provides an immersive platform for consumers to interact with virtual scenarios. Unfortunately, cybersickness remains a problem in VR. The uncomfortable effects of VR hinder its commercial expansion and the broader adoption of 3D virtual stores. Cybersickness has many causes, including personal characteristics, hardware interfaces, and operation behavior. This study develops a fuzzy-control anti-cybersickness intelligent system (FCACIS) with these factors dynamically and actively. The system retrieves the operation value and inferences the cybersickness symptom value (CSSV). When the CSSV exceeds the alarm value, a dialog mode is introduced to remind users to be aware of possible cybersickness. If the CSSV continues to increase, a cybersickness defense mechanism is activated, such as decreasing the field of view and freezing the screen. The experimental results revealed a significant difference in SSQ scores between subjects who navigated a 3D virtual store with and without the FCACIS. The SSQ scores of subjects with the FCACIS (SSQ = 20.570) were significantly lower than those of subjects without the FCACIS (SSQ = 32.880). The FCACIS effectively alleviated cybersickness for subjects over 40 years old. Additionally, the FCACIS effectively slowed the onset of cybersickness in men and women. The anti-cybersickness effect of the FCACIS on flat-panel displays was greater than that on HMDs. The symptoms of cybersickness for a 3DOF controller were also reduced.
Addressing Cybersecurity Challenges in Times of Crisis: Extending the Sociotechnical Systems Perspective
Authors: Mahmood Samreen , Chadhar Mehmood , Firmin Selena
Published: December 2024

Recent crises have significantly amplified cybersecurity challenges. Numerous studies have identified these challenges during major crises; however, empirical investigations using a sociotechnical systems (STS) theoretical perspective remain limited. Against this backdrop, this research study examines and categorizes cybersecurity challenges in the Higher Education and Research Sector (HERS) through the lens of STS theory. Utilizing a qualitative methodology, semi-structured interviews were conducted with cybersecurity experts and top managers. This study proposes an STS cybersecurity framework, classifying challenges into five subsystems: social, technical, political, economic, and environmental. This framework expands on previous literature by incorporating factors often overlooked, such as cybersecurity challenges arising from internal and external environmental conditions, legal and regulatory political factors, and national and global economic factors. This research provides valuable theoretical and practical insights applicable beyond the context of the recent crisis.
Real-Time Drivable Region Mapping Using an RGB-D Sensor with Loop Closure Refinement and 3D Semantic Map-Merging
Authors: Ha ChangWan , Yang DongHyun , Wang Gicheol , Kim Sung Chang , Jo HyungGi
Published: December 2024

Drivable region maps, created using a visual sensor, are essential for autonomous navigation because off-the-shelf maps do not reflect contemporary real-world conditions. This study presents a large-scale drivable region mapping system that is capable of capturing large-scale environments in real-time, using a single RGB-D sensor. Whereas existing semantic simultaneous localization and mapping (SLAM) methods consider only accurate pose estimation and the registration of semantic information, when loop closure is detected, contemporaneous large-scale spatial semantic maps are generated by refining 3D point clouds and semantic information. When loop closure occurs, our method finds the corresponding keyframe for each semantically labeled point cloud and transforms the point cloud into adjusted positions. Additionally, a map-merging algorithm for semantic maps is proposed to address large-scale environments. Experiments were conducted on the Complex Urban dataset and our custom dataset, which are publicly available, and real-world datasets using a vehicle-mounted sensor. Our method alleviates the drift errors that frequently occur when the agents navigate in large areas. Compared with satellite images, the resulting semantic maps are well aligned and have proven validity in terms of timeliness and accuracy.
Green Extraction and Valorisation of Bioactive Compounds from Food and Food Waste
Authors: Peron Gregorio
Published: December 2024

It has been estimated that more than 1 billion tons of food is wasted or lost globally every year, which is roughly one-third of the available food in the world [...]
Measurements and Analysis of Sound Reflections from Selected Building Façades
Authors: Zagubień Adam , Wolniewicz Katarzyna
Published: December 2024

This paper presents a study of the effect of the type of exterior cladding material of a building façade on the amount of sound reflection. It was verified whether there is a sound field undisturbed by reflections, similar to the free field, at a distance of 3 m from the building façade. Sound reflections from three building façade structures were tested: clinker brick, mineral plaster, and hard HPL. An equal geometry of the measuring field at selected real objects was used. It was determined that the differences in sound level results measured at distances up to 2 m and more than 2 m from the building façade are lower than the −3 dB correction specified in ISO 1996-2. Significant differences were observed comparing the measured sound level values in the undisturbed sound field with the levels recorded at a distance of 3 m from the building façade. It was proposed that the results of measurements made to control the levels of permissible noise in the environment should not be subject to the −3 dB correction.