bluuebunny/crossref_metadata_2025 huggingface dataset:
The History and Science of the Major Birch Pollen Allergen Bet v 1
Authors: Breiteneder Heimo , Kraft Dietrich
Published: July 2023

The term allergy was coined in 1906 by the Austrian scientist and pediatrician Clemens Freiherr von Pirquet. In 1976, Dietrich Kraft became the head of the Allergy and Immunology Research Group at the Department of General and Experimental Pathology of the University of Vienna. In 1983, Kraft proposed to replace natural extracts used in allergy diagnostic tests and vaccines with recombinant allergen molecules and persuaded Michael Breitenbach to contribute his expertise in molecular cloning as one of the mentors of this project. Thus, the foundation for the Vienna School of Molecular Allergology was laid. With the recruitment of Heimo Breiteneder as a young molecular biology researcher, the work began in earnest, resulting in the publication of the cloning of the first plant allergen Bet v 1 in 1989. Bet v 1 has become the subject of a very large number of basic scientific as well as clinical studies. Bet v 1 is also the founding member of the large Bet v 1-like superfamily of proteins with members—based on the ancient conserved Bet v 1 fold—being present in all three domains of life, i.e., archaea, bacteria and eukaryotes. This suggests that the Bet v 1 fold most likely already existed in the last universal common ancestor. The biological function of this protein was probably related to lipid binding. However, during evolution, a functional diversity within the Bet v 1-like superfamily was established. The superfamily comprises 25 families, one of which is the Bet v 1 family, which in turn is composed of 11 subfamilies. One of these, the PR-10-like subfamily of proteins, contains almost all of the Bet v 1 homologous allergens from pollen and plant foods. Structural and functional comparisons of Bet v 1 and its non-allergenic homologs of the superfamily will pave the way for a deeper understanding of the allergic sensitization process.
Study on the Erosion and Deposition Changes of Tidal Flat in Jiangsu Province Using ICESat-2 and Sentinel-2 Data
Authors: Wang Kaizheng , Li Huan , Zhang Nan , Zhang Jiabao , Zhang Xiaoyan , Gong Zheng
Published: July 2023

The ecological dynamics of tidal flats are subject to continuous transformations attributed to the interplay of the tidal erosion and sedimentation processes. Accordingly, the realization of a dynamic monitoring system for tidal flats holds significant importance in facilitating the judicious utilization and safeguarding of tidal flats resources. In this study, an integrated methodology was implemented to monitor and assess the tidal flats in Jiangsu province. Specifically, a collection of five multispectral images from the Sentinel-2 satellite was acquired, coupled with data derived from the ICESat-2 satellite. Through the application of advanced techniques, including convolutional neural networks and machine learning algorithms, a comprehensive combined model for inverting tidal flats topography was developed. The accuracy disparity between various model combinations was meticulously evaluated, thereby enabling the acquisition of detailed topography information encompassing the entirety of Jiangsu’s tidal flats for the year 2021. Comparative analysis against measured topographic data demonstrated that the overall accuracy of the combined model inversion surpassed 80%. Additionally, this study conducted an extensive investigation into the temporal evolution of tidal flats in Jiangsu by integrating data from 2008 to 2021, focusing particularly on the measured topography from 2008. Consequently, the study successfully delineated the various types of tidal flats present in Jiangsu and elucidated their corresponding evolutionary trends.
Uso de las redes sociales y su influencia en el desarrollo educativo
Authors: González Coronel Karina
Published: July 2023

Las redes sociales pueden facilitar la comunicación entre estudiantes y profesores, promover la colaboración, aumentar el acceso a los recursos educativos y fomentar el aprendizaje colaborativo. Además, las redes pueden ser una herramienta útil para la educación, ya que permiten la comunicación y colaboración entre estudiantes y profesores, el acceso a información y recursos educativos, y la creación de comunidades de aprendizaje. Varios estudios han demostrado que el uso moderado de estas plataformas puede aumentar la participación de los estudiantes, promover la colaboración y desarrollar las habilidades digitales necesarias en el siglo XXI. En la presente investigación se realizó una metodología de la revisión bibliográfica para obtener una visión general de los conocimientos existentes sobre el impacto que tiene en la actualidad las redes sociales en el ámbito educativo. Finalmente, los resultados muestran que las redes sociales pueden mejorar el desempeño de los estudiantes, la colaboración y la motivación intrínseca en el proceso de aprendizaje.
Molecular Environment of the Thermal Composite Supernova Remnant G352.7-0.1
Authors: Zhang Qian-Qian , Zhou Ping , Chen Yang , Zhang Xiao , Zhong Wen-Juan , Zhou Xin , Zhang Zhi-Yu , Vink Jacco
Published: July 2023

Galactic supernova remnants (SNRs) play an important role in our understanding of supernovae and their feedback on the interstellar environment. SNR G352.7-0.1 is special for its thermal composite morphology and double-ring structure. We have performed spectroscopic mapping of the 12CO and 13CO J = 2–1 lines toward G352.7-0.1 with the Atacama Pathfinder Experiment telescope. Broad 12CO lines are found in the northeastern ring at a local-standard-of-rest velocity range of ∼−50 to −30 km s−1, suggesting that the remnant is interacting with molecular clouds at ∼−51 km s−1. Thus, we adopt a distance of ∼10.5 kpc for this SNR. The momentum and kinetic energy of the shocked gas along the line of sight are estimated to be ∼102
M
☉ km s−1 and ∼1046 erg, respectively. We also find an expanding structure around the remnant, which is possibly related to the wind-blown bubble of the progenitor star. From Fermi-LAT data in the energy range 0.1–500 GeV, we find no gamma-ray counterparts to G352.7-0.1.
THE IMPACT OF LIFE-COURSE SOCIO-ECONOMIC POSITION ON QUALITY OF LIFE AT LATER AGES : EVIDENCE FROM ESTONIA
Authors: Sakkeus Luule , Saar Ellu , Rudissaar Uku
Published: July 2023

This study, guided by life-course theory and cumulative (dis)advantage theory, investigates the impact of the accumulation of socio-economic advantages and disadvantages, over the life course, on the quality of life (QoL) of the older population, and the mediating role of their current financial distress. In our study, we focus on the accumulation model. The study primarily uses data from Estonia in wave 4 of the Survey of Health, Ageing and Retirement in Europe (SHARE), with supplemental data from wave 5. Linear regression models were calculated based on two measures of quality of life : CASP-12 and life satisfaction. When measured by CASP-12, the socio-economic position in adulthood seems to play a more important role than that of childhood for the current quality of life of older people and even seems to compensate for it slightly when the current financial distress level is controlled for. However, when measured by life satisfaction, accumulated socio-economic (dis)advantages, especially in early youth, have a greater impact on the current quality of life of older people. It is important to acknowledge that different measures of QoL might yield different results.
An Analysis of Water Quality of Lake Perintis and Lake Limboto as Irrigation Water Sources in Gorontalo Province
Authors: Mahmud Marike , Lihawa Fitryane , Alitu Aryati , Husnan Rawiyah , Labdul Barry
Published: July 2023

This study aims to analyze the water quality of Lake Perintis and Lake Limboto as irrigation water sources in Gorontalo Province. This study was carried out by considering the importance of water from these two lakes for irrigating the rice fields. 2 lakes became the locations for sampling in this study, namely Lake Limboto and Lake Perintis. Because this study was an initial survey, the researchers only applied one-site and one-time sampling for each lake. The observed parameters were temperature, TDS, COD, turbidity, phosphate, pH, nitrate, iron, manganese, cyanide, arsenic, fluoride, chlorine, manganese, magnesium, calcium, sodium, potassium, total coliform, and E. coli. The analysis was carried out at the Water Quality Laboratory, Health Office of Gorontalo and Integrated Research & Testing Laboratory of Gadjah Mada University. The sampling for total coliform was carried out aseptically, while measurements in the laboratory applied the MPN method. The way of taking chemical and physical samples followed SNI 8995-2021. Furthermore, the collected data were analyzed following Government Regulation No. 22/2021 Appendix VI regarding Lake Water Quality Standards. In analyzing water for irrigation purposes, the researchers applied the Sodium Adsorption Ratio (SAR) classification. Results showed that the water quality of Lake Perintis and Lake Limboto did not meet the requirements stipulated in Government Regulation No. 22/2021 because the chlorine, COD, and phosphate parameters were above the required quality standard. In addition, we also found that the pollution level in Lake Limboto was higher than that of Lake Perintis. Moreover, the results of the SAR analysis indicated a score of 7.975 for Lake Perintis (classified in the low sodium criteria) and a score of 11.23 for Lake Limboto (classified in the medium sodium criteria).
Micropropagation of Sumatran Frankincense (Styrax Benzoin) Forest Plants Producing Bioactive Raw Materials for Medicine
Authors: Nurwahyuni Isnaini , Situmorang Manihar , Sinaga Riyanto
Published: July 2023

Preservation of tropical forest plants that have high economic potential, such as Sumatran benzoin (Styrax benzoin Dryander), is urgently carried out through the provision of quality seeds. The purpose of this study was to propagate the Sumatran Frankincense plant to produce good quality seeds to meet the needs of seeds for forest conservation purposes. The micropropagation technique was carried out using explants from selected parent plants of very good quality. Micropropagation through the use of explants from several parts of the plant aims to produce seeds with the same incense production quality as the parent plant. Explants were selected from the young leaves of the shoots. The experiment was conducted in a completely randomized design with two factors: concentrations of NAA (0-3 mg/L) and BAP (0-3 mg/L). The combination of NAA and BAP in culture media under optimal conditions proved to be effective in inducing callus and plantlet growth. The success of micropropagation has the potential to produce seeds of the same excellent quality as the parent plant in large quantities in a relatively short time. This technique is expected to be able to meet the conservation needs of people's forests and national forests, and in the long term will increase the production of frankincense as a non-timber forest commodity as raw material for medicine.