bluuebunny/crossref_metadata_2025 huggingface dataset:
Curvilinear subschemes of Segre varieties and the cactus rank
Authors: Ballico Edoardo
Published: September 2022

We study zero-dimensional linearly dependent subschemes W of the Segre variety with deg(W)≤5. If W is connected and curvilinear with arbitrary degree we give a strong restriction on the number of factors of the concise Segre containing W.
Anti-invariant Riemannian submersions from a locally Riemannian product manifold to any Riemannian manifold
Authors: Atceken Mehmet
Published: September 2022

In this paper, we define and study anti-invariant Riemannian submersions from a locally Riemannian product manifold onto a Riemannian manifold. We investigate the geometric properties of distributions which are involved from the definition of an anti-invariant Riemannian submersions in locally Riemannian product manifolds.
Fourier transform and the ideal of group algebra on the nilpotent Engel-Lie group
Authors: El-Hussein Kahar
Published: September 2022

We study noncommutative Fourier transform on the nilpotent Engel-Lie group G4 to solve some interesting problems of noncommutative analysis. In fact the finest structure of G4 can be shown as a semi-direct product of two real vector groups. This helps us to form our idea by constructing a new larger group in order to define the Fourier transform and to obtain the Plancherel formula on G4. Moreover we show that our methods lead us to construct several existence theorems for the invariant differential operators on G4 and on G4 × ℝ. Since the heat equation is invariant on G4 × ℝ, so a fundametal solution of this equation will be obtained. Finally we establish a theorem that gives a classification of all left ideals of the noncommutative Banach algebra L1(G4) of G4.
Rings in which every homomorphic image is a Noetherian domain
Authors: Bakkari Chahrazade
Published: September 2022

In this paper, we introduce a generalization of the well-known notion of a Noetherian ring which we call a Q-Noetherian ring. We investigate the transfer of the Q-Noetherian property to trivial ring extensions, localizations, homomorphic image of rings, direct product of rings, and amalgamated algebras along an ideal. These results provide examples of non-Noetherian Q-Noetherian rings, of non-coherent Q-Noetherian rings and examples of non-Q-Noetherian coherent rings. The article includes a brief discussion of the scope and precision of our results.
Lightlike hypersurfaces of a para-Sasakian space form
Authors: Perktas S. Yuksel , Kilic E. , Acet B. E.
Published: September 2022

In this paper, lightlike hypersurfaces of a para-Sasakian space form are studied. We obtain some non-existence results for screen semi-invariant lightlike hypersurfaces of a para-Sasakian space form. It is shown that a lightlike hypersurface is totally geodesic if and only if it is locally symmetric.
On the geometry of pseudo-slant submanifolds of a Kenmotsu manifold
Authors: Atceken Mehmet , Dirik Suleyman
Published: September 2022

In this paper, the geometry of pseudo-slant submanifold of a Kenmotsu manifold are studied. We research integrability conditions for the distributions which are involved in the definition of a pseudo-slant submanifold. The necessary and sufficient conditions are given for a pseudo-slant submanifold to be pseudo-slant product.
On n-strongly Gorenstein rings
Authors: Mahdou Najib , Tamekkante Mohammed
Published: September 2022

This paper introduces and studies a particular subclasses of the class of commutative rings with finite (resp. weak) Gorenstein global dimensions.
Set sharing and uniqueness of meromorphic functions
Authors: Banerjee Abhijit
Published: September 2022

The paper deals with the uniqueness problem of meromorphic functions sharing sets and the result of the paper improve, generalise and extend a recent result of Bhoosnurmath and Davanal [1].
The strongly Hopfian abelian groups
Authors: Chillali Abdelhakim , Abdelalim Seddik , Essanouni H.
Published: September 2022

Let A be an abelian group, A is said strongly hopfian if for all f ∈ End(A) we have the chain ker(f) ⊆ ker(f2) ⊆ ker(f3) ⊆ ker(f4) ⊆ ... is stationary. In this paper, we characterize strongly hopfian abelian group in the class of torsion abelian group. After we show that the p-component of strongly hopfian abelian group is strongly hopfian. But for the torsion part, we construct strongly hopfian abelian group whose the torsion part is not strongly hopfian.
Existence and stability for impulsive neutral stochastic integrodifferential equations with infinite delays
Authors: Diop Mamadou Abdoul , Ezzinbi Khalil , Zene Mahamat Mahamat
Published: September 2022

This work presents result on the existence and stability of mild solutions for some stochastic partial differential equations with infinite delay with non-lipschitz coefficients. We use the theory of resolvent operator devolopped in R. Grimmer (1982)[8] to show the existence and stability of the mild solutions. An example is provided to illustrate the results of this work.
Dynamics and oscillations of a class of cushing equations including gamma-distributed delays with a gap
Authors: Cherif Farouk
Published: September 2022

The stability of dynamical systems in presence of time-delay is a problem of big interest since the presence of a time-delay may induce instabilities, and complex behaviors for the corresponding schemes. In particular, the problem becomes even more difficult in the case when the delays are distributed. Besides, as we all know, many phenomena in nature have oscillatory character and their mathematical models have led to the introduction of certain classes of functions to describe them. Such a class form pseudo almost automorphic functions which a natural generalization of the concept of almost periodicity and almost automorphy. This paper studies the dynamics and oscillations of a class of the Cushing equations including gamma-distributed delays with a gap
x' (t) =-α x( t) +β(t) x( t-τ) + λ ( t) ∫0t g( θ ) x( t- θ ) dθ .
In particular, sufficient conditions are obtained to ensure the existence and stability of the unique pseudo almost automorphic solution for the Cushing equation with gamma-distributed delays .
Successive approximation of neutral stochastic partial integrodifferential equations with infinite delay and Poisson jumps
Authors: Zene Mahamat Mahamat , Diop Mamadou Abdoul
Published: September 2022

This work presents the result on existence, uniqueness of mild solutions of neutral stochastic partial integro-differential equations with infinite delay and Poisson jumps in real separable Hilbert spaces, We study the continous dependence of solution on the initial value. The nonlinear term in our equations are not assumed to Lipschitz continous. To obtain the results, we use the theory of resolvent operator devolopped in R. Grimmer (1982) and by using the method of successive approximation under sufficient condition.
On von Neumann-Jordan type constant and sufficient conditions for fixed points of multivalued nonexpansive mappings
Authors: Dinarvand Mina
Published: September 2022

In the present paper, we give some geometric conditions in terms of the von Neumann-Jordan type constant and the Dominguez-Benavides' coefficient which in turn are sufficient for the existence of fixed points of multivalued nonexpansive and 1-χ-contractive nonself mappings satisfying the inwardness condition and normal structure in a reflexive Banach space. Our main results improve some well known results in the recent literature.
Asymptotic orthogonality in normed spaces
Authors: Haddadi Mohammad Reza
Published: September 2022

In this paper we want to generalize the concept of best approximation and orthogonality in normed space and consider relation between them. Also we give important results for asymptotic best approximation in dual space.
Neutral stochastic functional differential equation driven by fractional Brownian motion and Poisson point processes
Authors: Lakhel El Hassan , Hajji Salah
Published: September 2022

In this note we consider a class of neutral stochastic functional differential equations with finite delay driven simultaneously by a fractional Brownian motion and a Poisson point processes in a Hilbert space. We prove an existence and uniqueness result and we establish some conditions ensuring the exponential decay to zero in mean square for the mild solution by means of the Banach fixed point principle.
On cyclic codes over F_{p^k} + vF_{p^k} + v^2 F_{p^k} + ... + v^k F_{p^k}
Authors: Ndiaye Ousmane , Gueye Cheikh Thiecoumb
Published: September 2022

In this paper, we investigate cyclic code over the ring Fpk + vFpk + v2Fpk + ... + vrFpk, where vr+1 = v, p a prime number, r > 1 and gcd(r,p) = 1, we prove as generalisation of [10] that these codes are principally generated, give generator polynomial and idempotent depending on idempotents over this ring as response to an open problem related in [12]. we also give a gray map and proprieties of the related dual code.
On some metabelian 3-groups realizable and principlaization
Authors: Talbi Mohamed , Derhem Aissa
Published: September 2022

Let G be some metabelian 3-group with abelianisation of type (3, 3). In this paper, we prove that G is realizable with some fields k which is the normal closure of a pure cubic field and we apply these results over G to study the capitulation problem of the 3-ideal classes of k.
Pade approximants and key lattices for decoding alternant codes
Authors: Abdelmoumen Khalid , Ben-Azza H. , Otmani Ayoub
Published: September 2022

In this paper we present two methods for algebraic decoding of alternant codes. The paper recalls fundamental facts of these codes and the concept of key equation introduced by Berlekamp on which decoding is based. The first method is based on Pade approximants. The second method consist of translating the key equation into a lattice over the ring of polynomials, called key lattice which depends on the syndrome, and then seek a shortest vector in this key lattice, with degrees constraints. The key lattice approach, following the fruitfull formulation of H. W. Lenstra, is based on a result of Grigor'ev showing that computing a minimal vector in the mentioned lattice is polynomial. The computational complexity of the proposed methods are given in terms of the error-correction capability of the codes and results in tractable polynomial time algorithms. A fast parallel version of the key lattice method is deduced.
The spectra of certain nonlinear superposition operators in the spaces of sequences
Authors: Halilovic Sanela , Vugdalic Ramiz
Published: September 2022

In this paper, we consider the nonlinear superposition operator F in lp spaces of sequences (1 ≤ p ≤ ∞), generated by the function
f(s,u)=a(s) + arctan u or f(s,u) = a(s) - arctan u.
We find out the Rhodius spectra σR(F) and the Neuberger spectra σN(F) of these operators and finally the radii of these spectra. The superposition operator generated by the function f(s,u) = a(s) ∓ arccot u appears to be a special case of above mentioned operator.
On some transformation formulas and their applications to partial theta function identities
Authors: Vidya K. N. , Somashekara D. D.
Published: September 2022

In this paper we derive three new transformation formulae for bilateral basic hypergeometric series. As applications of these transformation formulae, we deduce the well-known q-Guass summation formula and Sear's two 3φ2 transformation formulae. Further, we establish the reciprocity theorem of Ramanujan and its three variable generalization.
Essentially generalized lambda-slant Hankel operators
Authors: Datt Gopal , Mittal Anshika
Published: September 2022

The notion of an essentially generalized λ-slant Hankel operator of kth-order on the space L2 is introduced and its algebraic properties are discussed. The study is further carried to compression and essentially compression of generalized λ-slant Hankel operator of kth-order on the space H2.
Some results for classes of holomorphic functions
Authors: Ornek Bulent Nafi , Catal Batuhan
Published: September 2022

In this paper, a boundary version of the Schwarz lemma for classes K(α) is investigated. For the function f(z) = 1 + c1 z + c2 z2 + ... defined in the unit disc such that f(z) ∈ K(α), we estimate a modulus of the angular derivative of f(z) function at the boundary point b with f(b) = α. Also, we shall give an estimate below | f'(b)| according to the first nonzero Taylor coefficient of about two zeros, namely z = 0 and z0 ≠ 0. The sharpness of these inequalities is also proved.
Neutral stochastic functional differential evolution with varying-time delays driven by Rosenblatt process in Hilbert spaces
Authors: Lakhel E. , Boufoussi B. , Tlidi A.
Published: September 2022

In this paper we consider a class of time-dependent neutral stochastic functional differential equations with finite delay driven by Rosenblatt process in a real separable Hilbert space. We prove an existence and uniqueness result of mild solution by means of the Banach fixed point principle. A practical example is provided to illustrate the viability of the abstract result of this work.
Rings in which every nonzero projective ideal is regular
Authors: Bakkari Chahrazade , Omari Abdouljabbar Yahia
Published: September 2022

In this paper we introduce and investigate a class of those rings in which every projective ideal is regular. We establish the transfer of this notion to trivial ring extension, direct product, pullbacks, and amalgamation of rings along an ideal and then generate new and original families of rings satisfying this property.
A new generalization of (epsilon, epsilon v q)-fuzzy subrings and ideals
Authors: Ozturk Mehmet Ali , Jun Young Bae
Published: September 2022

Jun et al. [7] introduced more general form, so called δ-quasi-coincident with a fuzzy set, of ''quasi-coincident with'' relation (q) of a fuzzy point with a fuzzy set. Using this notion, the concepts of (∈ ,∈ ∨ q0δ)-fuzzy subrings/ideals, (∈ ,∈ ∨ q0δ)-fuzzy radicals and (∈ ,∈ ∨ q0δ)-fuzzy coset of a fuzzy set determined by an element of a ring are introduced, and related properties are investigated.
Kummer extension and Polya fields
Authors: Tougma Charles Wend-Waoga , Kientega Gerard , Tapsoba Theodore
Published: September 2022

A number field is called a Polya field if the module of integer-valued polynomials over its ring of integers has a regular basis. Let a ∈ ℤ, a ≠ 0 and p ≥ 3 be a prime number. In this paper, we characterize the number fields of the form ℚ(ζp, (a)1∕ p) which are Polya fields. We hence generalize results of [9]. New bounds for the number of ramified prime numbers in these fields are derived.
A digitial signature scheme based simultaneously on the DSA and RSA protocols
Authors: Zahhafi Leila , Khadir O.
Published: September 2022

In this paper, we propose a new digital signature scheme based on hard mathematical problems. We reenforce the DSA protocol by using the RSA cryptosystem. The security and complexity of the signature are analyzed.
On the numerical range of some nonlinear operators in l_p Spaces
Authors: Dedagic Fehim
Published: September 2022

The aim of this paper is to study properties of the numerical range W(T) of some nonlinear operators in Banach spaces of sequences ip.
On structure of D_5(G) for 2-group G.
Authors: Gupta Shalini , Kaur Jasbir
Published: September 2022

The objective of this paper is to discuss some conditions on a finite group G, under which D₅(G)=γ₅(G).
Rings in which every principal ideal is finitely presented
Authors: Bakkari Chahrazade , Omari Abdouljabbar Yahia
Published: September 2022

In this paper we introduce and investigate a class of those rings in which every principal ideal is finitely presented. We establish the transfer of this notion to the trivial ring extension, direct product and homomorphic image, and then generate new and original families of rings satisfying this property.
Multipliers on weighted group algebras
Authors: Mensah Yaogan , Issa Abudulai
Published: September 2022

Let G be a locally compact abelian group and let w be a weight on G. We study the multipliers on the weighted group algebra L1w (G) which is the Banach space L1(G, w) endowed with a new convolution product *w which depends on the weight w. We introduce a time-frequency shift like operators. We define a Fourier transform and we obtain among other results a convolution theorem and a Wendel like characterization of the studied multipliers.
Semi-slant Riemannian maps from cosymplectic manifolds into Riemannian manifolds
Authors: Kumar Sushil , Prasad Rajendra
Published: September 2022

In this paper we study semi-slant Riemannian maps from Cosymplectic manifolds into Riemannian manifolds. Several fundamental results on integrability of distributions and geometry of foliations are proved for such maps. Also we find the conditions for Riemannian maps to be totally geodesic and investigate some decomposition theorems. Finally, we give some examples of semi-slant Riemannian maps such that the characteristic vector field ξ is either vertical or horizontal.
Tingkat Keberhasilan Reposisi Tertutup pada Fraktur Antebrachii di RS Bethesda Yogyakarta pada Tahun 2007–2013
Authors: Budiman Johan , Sudharmadji  , Hariatmoko  , Pinzon Rizaldy Taslim
Published: September 2022

Forearm fracture defined as fracture that occurs in the forearm, where the radius and ulna bones are both broken. Forearm fracture is the most common type of fracture that occurs in children and adults. Traffic accident is one of the cause of this fracture. The initial approach in non-complicated forearm fracture is closed reduction with cast immobilization (conservative therapy). The aim of this study is to analyze the success rate of closed reduction of the forearm fracture at Bethesda Hospital of Yogyakarta. The study also examines the relationship between the type of fracture and the related success rate of closed reduction on forearm fracture as well as the distribution of forearm fracture at Bethesda Hospital, Yogyakarta.
This is a descriptive study with cross-sectional design. Radiographs and medical records of patients with forearm fracture at Bethesda Hospital, Yogyakarta were analyzed retrospectively in the period of 2007-2013. The measured variables are the change in the degree of angulation, apposition changes, gap occurrences, and the presence of overlap between radiological examinations before and after closed reduction. Medical records are also analyzed after reduction is done. Data is statistically analyzed using Chi-Square method.
The result shows that closed reduction of forearm fracture performed by emergency team of Bethesda Hospital Yogyakarta during the period of 2007-2013 was quite successful and there is a significant relationship between the type of fracture with the success rate of closed reduction of forearm fracture (p=0.003). Thus, closed reduction is a mainstay initial approach in the patients with forearm fracture. If it is not successful, then surgery can be performed.
Smoking, COPD, Infection and Lung Cancer: How Are They Interconnected?
Authors: Tanuwihardja Benjamin J.
Published: September 2022

A case of an elderly ex-smoker chronic obstructive pulmonary disease (COPD) patient with controlled type 2 diabetes mellitus (T2DM) as comorbid was followed-up for 10 years. His stable COPD in the course of time slowly declined to multiple acute exacerbation (AE)-COPD and multiple hospital admissions. High-dose systemic corticosteroids given during AE-COPD with prolonged oral steroids continuation led to depressed immunity that ended with severe immunosuppression, causing sepsis and chronic heart failure (CHF) with non-ST elevated myocardial infarction (NSTEMI) and worsening of COPD in his ninth year follow-up. This immunosuppression also triggered the emergence of lung cancer by allowing malignant cell to evade immune surveillance. Fortunately patient is survived and recovered to stable COPD.
A Rare Presentation of Penile Abscess Involving the Corpus Spongiosum and Anterior Urethra
Authors: Janardana Gede , Suarsana I Wayan
Published: September 2022

Penile abscess is an urological condition rarely described in literature. Multiple etiologies of penile abscess has been reported including idiopathic, complication of endourology procedure such as cavernosography, penile injection, penile instrumentation, trauma, gonorrhea complication, tuberculosis, priapism, as well as hematological spread of distant infection. A 42-year-old circumcised male presented for 2 days history of redness and painful swelling of the mid-distal ventral penile shaft and fever of 39°C. The patient had a history of a urethral catheterization 4 days before presentation as he had a problem of progressing difficulty to urinate since 7 days before. 600cc gross hematuria was observed at the initial catheterization. Physical examination showed edema, induration, and tenderness in the mid-distal ventral penile shaft. Skin break was found at the ventral side of coronal sulcus, excreting brownish-red discharge with pus. Laboratory examination showed normal WBC (7,720/mm3), normal random blood sugar (106 mg/dl). Urine analysis showed pyuria (15–16 WBC/hpf) and hematuria (4–5 RBC/hpf). The patient was treated with incision and drainage of the abscess, necrotomy, and systemic antibiotics for ten days. The remaining viable urethral tissues were stitched to the surrounding penile shaft skin in accordance to the “First stage of Johanson procedure” urethroplasty. Percutaneous cystostomy was also performed for urinary diversion. Most reported penile abscesses are cavernosal abscesses. In this patient, the abscess occurred in the corpus spongiosum in anterior urethra region, possibly caused by prior urethral instrumentation. Penile abscess after catheterization is an uncommon condition. Prompt drainage of purulent material and evacuation of necrotic area were the treatment goals. Surgical evacuation remains the first-line treatment.
Perkembangan Pemeriksaan Interferon-Gamma Release Assay (IGRA) dengan Metode T-SPOT.TB serta Aspek Klinis Pelaporan Hasil
Authors: Dewi Juliani
Published: September 2022

Latent tuberculosis infection (LTBI) screening and its treatment play important role in controlling tuberculosis (TB). Healthcare workers are known to be at high risk of latent TB infection. CDC suggests that every healthcare service should have TB controlling program. CDC recommends IGRA test for people who have history of contact with atypical mycobacteria patiens, screening in pregnancy, healthcare worker screening, and serial evaluation for Mycobacterium tuberculosis (MTB) infection.
IGRA test kits that are commercially available are QFT and T-SPOT.TB. Term “indeterminate” is used as a borderline value in QFT, but in T-SPOT.TB, it means the result is invalid. Term "borderline zone" is used in T-SPOT.TB, but not in QFT. T-SPOT.TB uses borderline zone which is designed to reduce uncertainty result in narrow range around single cut-off point. There are still no recommendations to use IGRA test for therapeutic monitoring.
Ekokardiografi pada Gagal Jantung
Authors: Rahmianti Nia Dyah , Trisna Ni Putu Alit
Published: September 2022

Heart failure (HF) is a leading cause of cardiovascular morbidity and mortality worldwide.  Clinical diagnosis of HF is often challenging because the symptoms and signs of HF are either too nonspecific or too infrequent. Echocardiography, given its safety, easy availability, and the ability to permit a comprehensive assessment of cardiac structure and function, is an indispensable tool in the evaluation and management of patients with heart failure (HF). It can also detect and define the hemodynamic and morphologic changes in HF over time and might be equivalent to invasive measures in guiding therapy. The early detection of heart failure has been facilitated by the assessment of global longitudinal strain, which is also useful in later heart failure for the assessment of left ventricular synchrony.The use of echocardiography has been associated with favorable outcomes, probably onthe basis of facilitation of appropriate therapy. Although the guidelines emphasize that no singletest satisfies all imaging requirements in heart failure, and other modalities can provide additional information about specific questions (especially tissue characterization), echocardiography is indispensable in the management of heart failure.
Clinical and Epidemiological Characteristics of Severe and Very Severe Pneumonia in Infants
Authors: Mustiko MD Hedi , Setyoningrum MD Retno Asih
Published: September 2022

Background: Childhood pneumonia is a leading cause of mortality and morbidity in developing countries. World Health Organization (WHO) stated that pneumonia is the cause of mortality of around 1.2 million children under 5 years per year. The high incidence of very severe pneumonia cases with preventable risk factors become the background of this study.Purpose: The aim of our study was to describe clinical and epidemiological characteristics of severe and very severe pneumonia in infants and children.Methods: This is a descriptive cross-sectional study. The study were conducted from January 2017 to December 2018. We obtained clinical and demographic data of each patient based on medical records.The diagnosis of pneumonia was made clinically based on the Indonesian Ministry of Health criteria. Prematurity was defined as babies born with gestational age less than 37 weeks, low birth weight was defined as babies with birth weight less than 2500 grams. The nutritional status of children is clinically and anthropometrically evaluated using 2006 WHO curve of weight-by-age. Results: A total of 465 patients were diagnosed with pneumonia during 48 months study. 212 patients were excluded and 253 pneumonia patients met the inclusion criteria, 140 patients with very severe pneumonia and 113 patients with severe pneumonia. Among 253 patients, 141 were boys. 125 patients were 2-5 months of age. 71 patients were born with low birth weight and 62 patients had history of preterm birth. There were 86 patients receiving exclusive breastfeeding and 138 patients with complete immunization status. There were 131 patients with moderate and severe malnutrition, and 127 patients with comorbidity factors. 94 patients developed pneumonia with suspected bacterial causative agents.Conclusion: Lower age, prematurity, low birth weight, poor nutritional status, exclusive breastfeeding, comorbidities, and suspected bacterial causative agents are common characteristics of severe and very severe pneumonia in infants and children in Dr. Soetomo Surabaya.
Serum Level of 25-Hydroxyvitamin D in Children with Epilepsy Receiving Long-Term Antiepileptic Treatment
Authors: Ismail Chasan , Irawan Roedi , Saharso Darto
Published: September 2022

Background: Long-term treatment with antiepileptic drugs (AED) requires monitoring of potential side effects, one of them is the decreasing in serum vitamin D level. Low serum vitamin D level is also a global health problem in healthy children. There are conflicting results regarding the low serum vitamin D level in epileptic children due to treatment with AED. Purpose: This study aimed to compare serum vitamin D level between healthy children and children with epilepsy receiving long-term AED treatment in Soetomo General Hospital. Methods: This was a cross-sectional study conducted in the pediatric neurology clinic of Soetomo general academic hospital from August 2018 to July 2019. Subjects are children ages 2-18 years with epilepsy receiving AED treatment for over 6 months (n=22), with healthy children as control (n=22). Peripheral serum 25-hydroxyvitamin D level were measured using enzyme-linked fluorescence assay (ELFA) method. The differences of those groups were analyzed by comparing the mean of 25-hydroxyvitamin D level of both groups using Anova and T-test (95% CI). Results: Low serum vitamin D level were identified in 27% children with epilepsy and 13% healthy children. The mean of serum 25-hydroxyvitamin D level in children with epilepsy and healthy children was 21.5 ng/ml (SD 8.41) and 34.3 ng/ml (SD 10.09), respectively. There was a significant difference between groups (p<0.05). Conclusion: Children with epilepsy receiving long-term AED treatment have lower level of serum 25-hydroxyvitamin D than healthy children.
Hemangioma Verukosa
Authors: Rinandari Ummi , Yustin Ellista Sari Endra
Published: September 2022

Verrucous hemangioma (VH) is a localized verrucous venous malformation comprising a capillary or cavernous hemangioma with proliferation reactions such as epidermal hyperkeratosis, acanthosis or papillomatosis also vascular proliferation and widening in the dermis to subcutaneous tissue. This disorder is usually found in the lower extremities and unilateral. It is often misdiagnosed as venous or lymphatic malformations. An 11 year-old boy presented with rough patches and blackish-red lumps on the right leg since birth. Four months prior, the lesion bled after being hit by ball and became rougher, thickened and darker thereafter. He was initially diagnosed with hemangioma and cryotherapy was performed, but there was no improvement after 6 cryotherapy treatment. A diagnosis of VH should be considered in the presence of erythematous papules, nodules, and plaques, especially those that are hyperkeratotic, present at birth, located at the lower extremities, and progressively enlarge after trauma or infection. Based on patient history, physical examination and laboratory results, the patient was diagnosed with VH. Excision surgery is the gold standard of VH management. The excision of the lesion must be deep and wide with a margin of 1 cm, to minimize recurrence. Treatment consists of combination of clobetasol propionate 0.05% and salicylic acid 5% ointment before excision was performed.
Diagnosis dan Terapi Terkini Multiple Myeloma
Authors: Savitri Merlyna
Published: September 2022

Multiple myeloma (MM) merupakan keganasan sel plasma yang ditandai oleh proliferasi klonal sel plasma ganas di sumsum tulang dengan protein monoklonal dalam serum dan/atau urine, serta disfungsi organ terkait disertai dengan morbiditas dan mortalitas substansial, berupa end-organ damage: gangguan ginjal, hiperkalsemia, lesi tulang litik, dan anemia. Dengan perkembangan terapi yang lebih baik, MM telah berubah dari penyakit yang tidak dapat diobati ke salah satu penyakit yang masih belum dapat disembuhkan, namun highly treatable dengan kebanyakan pasien dapat berobat rawat jalan. Kelangsungan hidup pada MM telah meningkat secara signifikan dalam 15 tahun terakhir. Hal ini disebabkan oleh adanya terapi terkini seperti bortezomib, thalidomide, dan lenalidomide. Dalam dekade terakhir, carfilzomib, pomalidomide, panobinostat, ixazomib, elotuzumab, daratumumab, isatuximab, dan selinexor juga telah disetujui oleh Food and Drug Administration (FDA) untuk pengobatan MM yang mengalami kekambuhan. Selain itu, adanya terapi autologous stem cell transplantation (ASCT) dapat meningkatkan median overall survival (OS) pasien MM sekitar 12 bulan dan sudah dapat dilakukan di Indonesia, khususnya di Surabaya (FK Unair- RSUD Dr. Soetomo-RS Unair).
Analisis In Silico pada VCO untuk Terapi Dermatitis Atopik
Authors: Mardiana  , Primadhanty B  , Adniana N  , Halim PK  , Didik H. Utomo  , Endra Yustin Ellistasari  , Suci Widhiati
Published: September 2022

Introduction: In silico analysis is used in the early stages of drug discovery to speed the rate of discovery that is considered cost and time-efficient. Virgin Coconut Oil (VCO) is a treatment option for atopic dermatitis because it has function to repair skin barrier and as anti-inflammation. Objective: To evaluate the VCO content using computational in silico analysis for the treatment of atopic dermatitis. Methods: The active compounds of Cocos nucifera extracted from KNApSAcK database were predicted experimentally and analyzed computationally using Simple Molecular-Input Line-Entry System (SMILES), Prediction of Activity Spectra for biologically active Substances (PASS) server, and Search Tool for Interactions of Chemicals (STITCH).
Results: There are 19 active compounds found in VCO. The analysis shows that VCO has free fatty acid (FFA) protein which acts as a receptor for long and medium chain saturated and unsaturated fatty acids. The highest potential bioactivity of active VCO compounds was as antieczema, with the most important component was linoleic acid, with an average value of probable to be active (Pa) = 0.872, predicted to be highly potential in computational and laboratory tests.
Conclusion: Based on this study, we recommend the use of VCO as treatment for atopic dermatitis because VCO has anti-inflammatory potential bioactivity, histamine inhibitor, improves skin barrier function and antieczema which could improve the outcome of atopic dermatitis.
Laporan Kasus Acrodermatitis Enteropathica pada Anak 5 Tahun dengan Level Zink Serum Normal
Authors: Nareswari Adniana , Mochtar Moerbono , Widhiati Suci , Kusumawardani Arie , Ellistasari Endra Yustin , Julianto Indah
Published: September 2022

Acrodermatitis enterophatica (AE) is an inherited or acquired condition associated with zinc malabsorption. Clinical symptoms of AE are periorificial and acral dermatitis, alopecia, and diarrhea. Serum zinc levels usually decrease in AE patients. A 5-year-old boy presented with crusted erosion on the face, trunks and extremities that have been appeared for one year and worsened last month. It also accompanied by hair and eyebrow loss, diarrhea, and eating disorder. Patient was also malnourished. Dermatovenereology examination showed papules, patches, multiple erythematous plaques with squama, erosions with brownish yellow crust above located on perioral, periorbital, posterior trunk, inguinal, perianal, cubital, popliteal and dorsum pedis region. The oral region showed stomatitis and cheilitis. The orbital region showed conjunctival injection and eye discharge. The scalp, eyebrows and lashes showed total alopecia. Laboratory test showed normal serum zinc levels and decreased levels of alkaline phosphatase. The patient was diagnosed with acquired form of AE. Clinical improvement was seen after zinc supplementation. The diagnosis of AE cannot be made only by low serum zinc levels. If a classical triad of AE was found, we must be able to recognize it immediately, thus prompt and appropriate therapy could be given.
Manifestasi Klinis Covid-19 pada Kulit
Authors: Iswinarno Doso Saputro  , Medisa Primasari
Published: September 2022

Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) is a strain of coronavirus that causes Coronavirus Disease 2019 (Covid-19). The first case was reported in the city of Wuhan, China, through the consumption of bush meat which presumed to be the reservoir of the virus. Human-to-human transmission occurs through respiratory droplet inhalation or touching contaminated surfaces, then without washing hands, virus may enter the body through contact with mucous membrane in the eyes, nose, or mouth. Covid-19 manifested in various level of severity among individuals, from mild, severe, critical, or even symptom-free. Clinical manifestations are not specific and vary among individuals. Common symptoms are fever, cough, fatigue, shortness of breath, upper respiratory symptoms, gastrointestinal disorders, loss of taste or smell, also presentation of skin manifestation. Skin manifestation associated with Covid-19 also varies and may appear at different times without being followed by other symptoms. Laboratory tests, imaging test, and identification of genetic material of SARS-CoV-2 are necessary to confirm the diagnosis of COVID-19.
Closing the Gap of Unmet Needs in Inflammatory Pain Management: Case Series of Predimenol for Pain
Authors: Rizaldy Pinzon
Published: September 2022

Chronic inflammatory pain is major medical problem worldwide. Nonsteroidal anti-inflammatory drugs (NSAIDs) and selective cyclooxygenase (COX)-2 inhibitors are commonly used medications to treat chronic pain. However, these agents have been associated with serious gastrointestinal, renal and cardiovascular adverse effects. This limitation indicates a clear unmet need in terms of safety of current treatment options for the management of chronic inflammatory pain. Those adverse effects may caused by overlapping roles of COX-1 and COX-2 in physiological and pathophysiological processes. Predimenol is a herbal medicine that can be used to treat pain. Recent findings showed that these phytochemicals may directly act upon several inflammatory processes and offer compelling evidence that predimenol could reduce pain and inflammation. We report two cases and short review of the use of predimenol for pain management. Our review showed that predimenol formulations could be a valuable alternative treatment to relieve symptoms of pain with good safety profile. Further researches through large, high quality RCTs to investigate the clinical benefit of predimenol for pain management are needed.
Terapi Probiotik Pada Akne Vulgaris
Authors: Reti Anggraeni  , Arie Kusumawardani
Published: September 2022

Akne vulgaris (AV) adalah penyakit inflamasi kronik kulit yang mengenai unit pilosebasea dan mengakibatkan kelainan noninflamasi berupa komedo terbuka (blackhead) dan komedo tertutup (whitehead) serta adanya tanda inflamasi seperti papul, pustul dan nodul. Banyak faktor yang berkontribusi terhadap patogenesis AV termasuk mikrobioma kulit seperti Propionibacterium acnes (P. acnes) dan Malassezia spp. yang dikaitkan dengan perkembangan AV melalui pengaruhnya terhadap sekresi sebum, pembentukan komedo dan respons inflamasi. Terapi antibiotik dengan target P. acnes telah lama menjadi terapi utama AV dimana terapi tersebut ternyata dapat mempengaruhi komposisi dari mikrobioma kulit. Seiring dengan meningkatnya resistensi antibiotik, pengetahuan tentang mikrobioma kulit yang terkait dengan AV menjadi sangat relevan dan penting untuk menjadi dasar alternatif pilihan terapi AV.
Hubungan Lama Rawat Inap dengan Kejadian Depresi pada Anak Usia 10–18 Tahun yang Dirawat di RSUD Dr. Soetomo Surabaya
Authors: Rika Hapsari  , Mira Irmawati  , Ahmad Suryawan  , Irwanto
Published: September 2022

Background: Depression can occur in children with chronic disease who are hospitalized. Prolonged hospitalization correlates with higher prevalence of depression that may affect clinical outcome. The aim of this study is to determine the correlation between length of hospitalization and depression in children with chronic disease. Method: This cross-sectional study was conducted at Dr. Soetomo Hospital Surabaya, from January to March 2019. Children ages 10-18 years with chronic diseases such as oncology hematology, chronic kidney disease, and liver disease hospitalized for ≥7 days were screened for depression. Children with a history of previous depression or other mental illnesses were excluded. Depression was evaluated using the Children’s Depression Ratting Scale-Revised (CDRS-R) questionnaire. Statistical analysis using comparative test and correlation test with p value <0.05. Results: A total of 58 children were treated in the pediatric ward Dr. Soetomo Hospital Surabaya, 50 met the inclusion criteria and 8 were excluded. Subjects consist of 27(54%) boys and 23(46%) girls. The mean age was 11.8±0.39 years. The average duration of treatment was 16±1.6 days. Depression screening found 39(78%) children with varying degrees of depression, 17(34%) moderate depression and 22(44%) severe depression with an average CDRS-R score of 45.2±2.3. The results showed 65.5% of children who were hospitalized for 7-14 days and 95.2% of children who were hospitalized for more than 14 days had depression (OR value=10.52; 95% CI; 1.227-90.311; p = 0.016). Correlation test results between the length of stay and CDRS-R score (r=0.502, p<0.001). Conclusion: Children with chronic disease who are hospitalized more than 7 days have higher risk of depression.
Laporan Kasus Terapi Kombinasi Kuretase dan Cimetidine Oral pada Pasien Moluskum Kontangiosium
Authors: Annisa Fildza Hashfi  , Nurrachmat Mulianto  , Winda Wijayanti  , Niluh Wijayanti
Published: September 2022

Background: Molluscum contagiosum is an infectious disease of the skin caused by poxvirus. The virus may be transmitted through direct skin and mucous membrane contact, including sexual contact, and through contaminated fomites. The prevalence of sexually transmitted molluscum contagiosum has increased in recent years. This disease causes anxiety and discomfort for the patients. Diagnosis of molluscum contagiosum is made based on history taking, physical examination, dermoscopic examination, and histopathological examination. Proper diagnosis and management can help to reduce risk of recurrence. Case: A 26-year-old woman with main complaint of developing shiny white rashes on her thighs and buttocks since 3 months ago. The nodules felt itchy yet painless. At first, only 4 papules appeared on the buttocks. In the last month, the nodules multiplied and spread to the thighs. The patient had tried to squeeze the nodule and rice-like white mass came out. The patient had history of unprotected sexual intercourse. Dermatological examination on the right and left femoral regions and the gluteus, found that there were discrete, multiple shiny white pearl-like papules of 0.1-0.5 cm in size, smooth surface, well-defined, dome-shaped, umbilicated with caseous plug. Dermoscopic examination showed a white to yellow polylobular appearance with crown vessel. Histopathological examination showed an appearance of intracytoplasmic eosinophil inclusion bodies (molluscum bodies). Discussion: Clinical findings such as discrete multiple, pearl-colored, umbilicated dome-shaped papules, are characteristic features of molluscum contagiosum. Dermoscopic examination results and histopathological images also support the diagnosis of molluscum contagiosum. Treatment was carried out using curettage on the lesions and prescription of oral cimetidine 2x800 mg for 2 months. No recurrence was found after 5 months of follow-up
Peningkatan Motivasi Belajar Peserta Didik melalui Bimbel pada Masa Pandemi Covid-19
Authors: Ahmad Muzaqi  , Ratih Koesoemo , Sutopo Anam
Published: September 2022

Salah satu upaya untuk meningkatkan potensi peserta didik yaitu dengan bimbingan belajar. Dalam beaktivitas dilandasi dengan dorongan untuk menggapai sebuah tujuan. Pendorong yang ada pada manusia ini yaitu motivasi. Dalam pemberian motivasi bisa dilakukan oleh siapapun dan kapapun sepeti mahasiswa yang mengabdi di sekolah. Pengabdian masyarakat dalam suatu daerah tertentu seperti daerah terpencil memiliki tujuan untuk membantu masyarakat pada daerah tertentu tanpa mengharapkan imbalan apapun dan dalam bentuk apapun. Pelaksanaan kegiatan ini ilaksanakan di SMPN 2 Lembeyan, Kecamatan Lembeyan, Kabupaten Magetan. Digunakan metode advokasi. Hasil dari pengabdian ini yaitu bimbingan belajar yang dilakukan kepada siswa SMPN 2 Lembeyan, membeikan motivasi kepada peserta didik, dan kegiatan pemberian hadiah yang berupa hadiah maupun pujian. Adanya pengabdian yang dilakukan oleh mahasiswa Kampus Mengajar ini dil-akukan untuk menjaga semangat belajar peserta didik di masa pandemi Covid-19.
Realisasi Bisnis Digital Siswa Guna Mewujudkan Profil Pelajar Pancasila sebagai SMK Pusat Keunggulan
Authors: Sholihatinnisa Intan , Nurcahyono Novi Andri , Anastia  , Fitria Riska
Published: September 2022

Sekolah Menengah Kejuruan memiliki tujuan khusus dalam mencetak lulusan- lulusannya, tidak hanya teori yang diberikan kepada siswanya, namun juga praktik terjun langsung ke lapangan, merupakan suatu keharusan yang diterima siswa ketika berada di jenjang Sekolah Menengah Keju-ruan. Dengan realisasi kompetensi keahlian yang ada, siswa dipersiapkan dengan baik untuk terjun langsung ke dunia kerja. Selain itu, hal ini juga mendukung terwujudnya siswa yang mandiri dan suka bergotong royong, yang merupakan salah satu profil pelajar Pancasila. Selanjutnya, ketika siswa melaksanakan PKL di suatu industri, maka hal itu akan menambah relasi dunia kerja baik untuk sekolah maupun untuk siswa itu sendiri. Sehingga, ketika lulus dari sekolah, dan berencana langsung terjun ke dunia kerja, siswa memiliki relasi-relasi yang mempermudah pencapaian tujuannya. Bentuk nyata yang dilakukan SMK Negeri 2 Kota Sukabumi dalam mengupayakan hal tersebut adalah bekerja sama dengan Alfamart, dimulai dengan bimbingan yang didapat siswa me-lalui program Alfaclass, sehingga siswa memiliki keahlian yang diperlukan, khususnya untuk siswa yang berada di kelas kompetensi keahlian Bisnis Daring dan Pemasaran. Hasil akhirnya, Alfamart akan merekrut siswa-siswa tersebut.
Upaya Meningkatkan Literasi Siswa melalui Program Kelompok Belajar pada Masa Pandemi Covid-19
Authors: Nurtianingsih Tika , Indratyaseta Arsihti Dwi Putri , Putra Romi Iriandi , Indah Tiara
Published: September 2022

Pandemi Covid-19 ini telah mengganggu kegiatan belajar mengajar di berbagai sekolah termasuk di SMP N 2 Sambi, berbagai kebijakan telah dilakukan oleh Pemerintah Indonesia untuk mengatasi penularan Covid-19. Salah satu kebijakan tersebut adalah penerapan pembelajaran daring. Program kelompok belajar ini dilaksanakan berdasarkan permasalahan yang dialami siswa. Tujuan dari penelitian ini adalah untuk memaksimalkan pemahaman terhadap pembelajaran yang diberikan oleh sekolah secara daring. metode penelitian ini menggunakan metode kualitatif deskripsi. Temuan yang dihasilkan dalam penelitian program kelompok belajar adalah adanya kegiatan program kelompok belajar untuk siswa SMP N 2 Sambi ini sangat bermanfaat karena dapat membantu para peserta didik memahami materi pembelajaran, meningkatkan motivasi siswa dalam belajar dan tetap semangat meraih prestasi. Secara konkrit ditunjukkan dengan peningkatan literasi siswa SMP N 2 Sambi yang terlihat dari antusias membaca buku fiksi maupun nonfiksi, sehingga permasalahan belajar di rumah bagi siswa-siswi SMP N 2 Sambi dapat teratasi.
Program Home Visit sebagai Upaya Peningkatan Kemampuan Literasi dan Numerasi Siswa SMP Negeri 2 Sumowono
Authors: Umi Astutik Nuskhatul Huwaida , Sufanti Main
Published: September 2022

Pada September 2021, Siswa Sekolah Menengah Pertama akan segera mengikuti Asesmen Nasional (AN) sehingga salah satu tugas mahasiswa Kampus Mengajar yaitu membantu meningkatkan kemampuan literasi dan numerasi siswa. SMP Negeri 2 Sumowono merupakan salah satu sekolah sasaran Kampus Mengajar Angkatan 2 yang terletak di daerah 3T, tepatnya di daerah pegunungan. Salah satu program mahasiswa kampus mengajar pada sekolah ini adalah program Home Visit. Tujuan program tersebut memberikan pendampingan belajar siswa kelas VIII dalam meningkatkan literasi dan numerasi siswa calon peserta Asesmen Nasional (AN).  Penelitian ini menggunakan metode penelitian tindakan. Hasil pendampingan belajar menunjukkan bahwa terdapat peningkatan hasil belajar siswa ditandai dengan rata-rata nilai siswa setelah mendapatkan pendampingan belajar melalui program Home Visit mengalami peningkatan yang signifikan dalam kemampuan literasi dan numerasi. Pelaksanaan Home Visit menggunakan beberapa metode pembelajaran diantaranya, Penggunaan metode diskusi untuk literasi dan metode jarimatika untuk numerasi. Penggunaan metode ini efektif untuk meningkatkan kemampuan belajar siswa.
Polymorphism for Interleukin-4 (-590 C/T) Promoter: Non-Association with Endometriosis
Authors: Hairunisyah Rika , Fatimah Siti
Published: September 2022

Endometriosis is a benign gynecological disorder that often occurs in women of reproductive age, usually characterized by endometrial epithelium and stroma outside their usual location. It is estimated that this disease affects 56% of women worldwide. Various types of cytokines are associated with endometriosis, including interleukin IL-4, which inhibits the production of proinflammatory cytokines that stimulate active B cells and T cell proliferation, the differentiation of B cells into plasma cells. Il-4 promoter region polymorphism (-590C/T) is involved in genetic susceptibility to endometriosis. This study aims to determine whether Gen IL-4 (-590C/T) polymorphism indicates endometriosis. This study is an analytical observational study conducted at the Laboratory of Molecular Biology in Palembang City in August 2021, with the approach of Case-Control study. There were 70 samples divided into two groups, namely 35 cases and 35 controls. Determination of genotypes and alleles using PCR-RFLP and chi-square analyzed data to determine the relationship. The results showed no significant difference. The genomorphism of the Interleukin-4(-590C/T) gene cannot be used to indicate endometriosis susceptibility.