bluuebunny/crossref_metadata_2025 huggingface dataset:
Detection of Postcolonoscopy Colorectal Neoplasia by Multi-target Stool DNA
Authors: Ebner Derek W. , Eckmann Jason D. , Burger Kelli N. , Mahoney Douglas W. , Bering Jamie , Kahn Allon , Rodriguez Eduardo A. , Prichard David O. , Wallace Michael B. , Kane Sunanda V. , Finney Rutten Lila J. , Gurudu Suryakanth R. , Kisiel John B.
Published: June 2021

INTRODUCTION:

Significant variability between colonoscopy operators contributes to postcolonoscopy colorectal cancers (CRCs). We aimed to estimate postcolonoscopy colorectal neoplasia (CRN) detection by multi-target stool DNA (mt-sDNA), which has not previously been studied for this purpose.

METHODS:

In a retrospective cohort of patients with +mt-sDNA and completed follow-up colonoscopy, positive predictive value (PPV) for endpoints of any CRN, advanced adenoma, right-sided neoplasia, sessile serrated polyps (SSP), and CRC were stratified by the time since previous colonoscopy (0–9, 10, and ≥11 years). mt-sDNA PPV at ≤9 years from previous average-risk screening colonoscopy was used to estimate CRN missed at previous screening colonoscopy.

RESULTS:

Among the 850 studied patients with +mt-sDNA after a previous negative screening colonoscopy, any CRN was found in 535 (PPV 63%). Among 107 average-risk patients having +mt-sDNA ≤9 years after last negative colonoscopy, any CRN was found in 67 (PPV 63%), advanced neoplasia in 16 (PPV 15%), right-sided CRN in 48 (PPV 46%), and SSP in 20 (PPV 19%). These rates were similar to those in 47 additional average risk persons with previous incomplete colonoscopy and in an additional 68 persons at increased CRC risk. One CRC (stage I) was found in an average risk patient who was mt-sDNA positive 6 years after negative screening colonoscopy.

DISCUSSION:

The high PPV of mt-sDNA 0–9 years after a negative screening colonoscopy suggests that lesions were likely missed on previous examination or may have arisen de novo. mt-sDNA as an interval test after negative screening colonoscopy warrants further study.
Europeana, EDM, and the Europeanisation of Cultural Heritage Institutions
Authors: Capurro Carlotta , Plets Gertjan
Published: June 2021

Over the past two decades, the European Commission has mobilised cultural heritage to bolster a European identity. One of the main flagship initiatives promoted to this end has been Europeana, the most extensive digital cultural project financed by the EU. At the core of the project stands europeana.eu, a digital cultural portal aggregating metadata provided by national and local heritage institutions. Central in our analysis is the Europeana Data Model (EDM). Using standardised thesauri and vocabularies, EDM offers the possibility to create a semantic contextualisation for objects, allowing semantic operations on the metadata and their enrichment with Linked Open Data on the web. Due to its overarching nature, EDM cannot deliver the granularity that cultural heritage institutions need when documenting their resources. Nonetheless, heritage institutions accept to sacrifice accuracy to have their information represented in a Europewide collection. We study how this digital heritage infrastructure was designed to enact a sense of Europeanness amongst national and local institutions. Policy documents, ethnographic research and a systematic survey amongst the European heritage institutions enabled us to trace how a standardised European metadata structure plays a role in governing local and national heritage institutions. The EDM might enable heritage stakeholders to benefit from Europeana’s online exposure while enacting a European mindset. Ultimately, this study of the metadata model enriches the debate on the EU’s cultural heritage politics, which has not fully explored the role of the digital. At the same time, it also taps into debates about infrastructure and digital governmentality.
nombre no es solo un referente
Authors: Reyes Contreras Miguel
Published: June 2021

n/a
Placenames of indigenous origin in Acre-Brazil
Authors: Costa Rozangela de Melo Martins da , Sousa Alexandre Melo de
Published: June 2021

Toponymy, a discipline that studies place names, is one of the branches of Onomastics: science responsible for the study of proper names. This study aims to trace a profile of toponyms of indigenous origin in the rural area of Acre, analyzing toponymic motivations related to fauna, flora and hydrography in Acrean geographic features.  This corpus – collected in the maps provided by IBGE, with a scale of 1: 250,000 and 1:1,000,000 – was based on the theoretical-methodological proposal by Dick (1990, 1992), especially regarding the taxonomic model, composed of 27 taxa, subdivided into physical and cultural categories, and as to the catalogue and storage of toponymic database (DICK, 2004). The results revealed that, out of 392 toponyms, 74% are names linked to physical and geographic characteristics, 20% concerning cultural factors and 6% were unclassified. The research showed that toponymic motivation is mainly based on flora, fauna and hydrography predominantly from Tupi language origin.
Language and culture in dimension
Authors: Lopes Tereza Tayná Coutinho , Ferreira Marília
Published: June 2021

Onomastic studies in general—and the studies of the onomastic systems of indigenous languages in particular—require interdisciplinary investigations that address properly the diversity inherent in the field. In this vein, the present work discusses how linguistic concepts dialogue with anthropology and ethnography in the study of the onomastic system of Parkatêjê, an indigenous language spoken by the people of the same name, who currently inhabit the area called Reserva Indígena Mãe Maria (RIMM), close to the municipality of Marabá (Pará, Brazil). We will discuss aspects observed in the description of the anthroponyms known and used mostly by native speakers of the Parkatêjê language. The methodology of the study consisted of bibliographic research and ethnographic research with data collection in the indigenous area inhabited by the indigenous communities in question.
Name-giving motives in Lithuania and Brazil
Authors: Butkuvienė Karolina , Petrulionė Lolita , Seide Marcia Sipavicius , Valiulienė Edita
Published: June 2021

TThis research aims at analysing and comparing the motives for choosing the first name of a child in Lithuania and Brazil in the years 1958-2016. By combining qualitative and quantitative methods and applying social and cultural approaches, it reveals that different countries and cultures have both similar and divergent trends in name-giving practices. The most remarkable similarity in both countries and cultures is both the predominance of an aesthetic motiveand the desire to honour a relative, a friend, or a famous person. These trends are presumably related to universal aspects of naming practices. The aesthetic motiveis related to processes of cultural globalization, while the honour-oriented motivepoints to the significance of traditional naming patterns. The greatest difference between Lithuanian and Brazilian data is in the frequency of name choices due to patriotism, religion, name uniqueness or naming a child after a fictional character. Such divergent results are explained by different social values in each society and different cultural and historical experiences. In addition, the research proves that the first names do have meaning; however, it is not purely conceptual or lexical, as they rather bear individual connotations.
Seguridad cooperativa: paradigma 2018-2022 para Colombia
Authors: Cano Cuevas Diego Fernado , Hernández Cubides Jairo Andrés
Published: June 2021

En este artículo se analiza el concepto de seguridad cooperativa adoptado por Colombia en la política de defensa y seguridad propuesta en el Plan Nacional de Desarrollo 2018-2022 “pacto por Colombia, pacto por la equidad”, esto se hace tomando como referencia el marco conceptual de la taxonomía de la seguridad nacional. Se busca vislumbrar si la seguridad cooperativa y lo que se ha intentado implantar con ella es suficiente para la etapa actual de posacuerdo que vive Colombia, o si, por el contrario, la razón por la que el Estado colombiano ha tomado este concepto recae en la necesidad de llegar a un consenso institucional o presiones de actores intergubernamentales como la OTAN, olvidándose que Colombia vive elementos coyunturales propios que no recoge del todo el concepto de seguridad cooperativa. Por eso, se expondrá el debate de las relaciones internacionales sobre la seguridad y sus conceptos, dentro de los cuales está la seguridad cooperativa; en la segunda parte se expondrán diferentes factores que limitan la cooperación en temas de seguridad al interior del país, por lo cual, se afrontan restricciones para alcanzar un marco cooperativo, limitando la efectividad de la seguridad cooperativa a la hora de enfrentar la conflictividad actual.
Single and Multi-message Sexuality Education: Improving Implementation and Evaluation of Group-based Programs
Authors: Rue Lisa , Floren Michael , Floren Kiley , Rhoades Galena , Walker Elaine , Owen Jesse
Published: June 2021

Objective: In this study, we isolated primary messaging strategies of sexuality education curricula to improve tailored delivery of group-based interventions. Specifically, our aim was to define single-message programs (eg, messaging about avoiding sexual risk or messaging about reducing sexual risk) and multiple-message programs (eg, avoiding sexual risk and reducing sexual risk), and to investigate their comparative effectiveness. Methods: We used a descriptive approach with publicly available data from US Department of Health and Human Services-funded teen pregnancy prevention programs to categorize 16 different curricula as single-message or multiple-message. We coded primary messages using a curriculum mapping rubric and scoring that was evaluated by a panel of experts for content validity. Forest plots compared behavioral outcomes. Results: Scores for primary messages achieved inter-rater reliability of 91%-100%; curricula were scored on 20 items within each category to calculate mean scores. Spearman correlations for items ranged from .43 to .93. Conclusions: No outcome differences were observed between single- or multi-message programs. Effective delivery of primary messaging may rely more on identifying moderators of classroom climate typically underrepresented in evaluations of school-based programs.
Prospective scenarios analysis Impact on demand for oil and its derivatives after the COVID-19 pandemic
Authors: Rodrigues Marcus Vinicius Gonçalves , Duarte Thamires Eis , Dos Santos Marcos , Gomes Carlos Francisco Simões
Published: June 2021

Goal: This paper aims to illustrate one of the strategies found in the literature to deal with uncertainties: prospecting scenarios in the demand for oil derivatives after the COVID-19 pandemic (identifying the desirable scenario, the undesirable and the trend, at a national level in the Brazilian market) and proposing a corresponding strategy plan for each prospection in order to minimize the resumption impacts.

Design / Methodology / Approach: This study was carried out with relevant indicators of the oil and gas industry (downstream). Commercialization data (from 2017 to 2020) were compared in order to verify the pandemic impacts. After collecting the data, we used the Momentum approach to prospect the scenarios, suggesting a strategic action plan for each prospection.

Results: The results reveal that, regardless the post-pandemic scenario that we will encounter, the industries belonging to the oil and gas sector will have to define strategies and implement solid action plans to remain competitive in the market. It was also possible to note that the action plan for the desirable and trend scenario has synergy.

Limitations of the investigation: The results obtained in this research refer only to the Brazilian scenario, more specifically to the downstream sector of the oil and gas industry and may differ from other sectors or regions.

Practical implications: This research provides ways for oil and gas companies to be prepared for the post-pandemic future, thus remaining competitive in the market. In addition, as a result of applying the Momentum method, it is possible to see how the sector's indicators relate to each other through the cross-impact matrix.

Originality / Value: This is an unprecedented study that allows the downstream oil and gas companies to be better prepared to the post-COVID-19 scenario. It adds value not only to the oil and gas industry but also to other industries, since it is possible to replicate the method presented here in other contexts with different databases.
Identification of Microplastic Composition on Clams (Gafrarium tumidum) and Sediments in Seribu Island, Pari Island Area, DKI Jakarta
Authors: Tubagus Winesti , Sunarto Sunarto , Ismail Mochamad Rudyansyah , Yuliadi Lintang Permata Sari
Published: June 2021

Microplastic is one of the pollutants that can contaminate marine biota even spread in sea waters and coastal substrate because of the sizes ranges to 10 μm - 2 mm. This pollutant is spread in marine waters and found in the area of Seribu Island, Pari Island Area, DKI Jakarta. This research aims to identify the amount of abundance, type, size, and color of microplastic that was found in sediment and shell samples. The research method used was a survey method and laboratory analysis. The method consists of three parts, namely field data collection, identification using a microscope, and describing the results of identification.  All sediment and shell samples were identified as being contaminated with microplastics. Microplastic are found in fiber, fragment, and film type. That color found including black, yellow, red, blue, green, chocolate, and clear. The most dominant microplastic color is black and the most dominant microplastic size is the small size group. The highest microplastic abundance in sediment samples from 3 stations is found in samples taken by station 2 with an average of 43.67 particles. 100 g-1 of dry sediment and the most dominant type is the fiber type from all sediment samples. The most dominant type of mussels sample is fragment type and the average abundance of microplastics in the highest sample of mussels is worth 17.33 particles.ind-1.
Salmonella Paratyphi Infection: Use of Nanopore Sequencing as a Vivid Alternative for the Identification of Invading Bacteria
Authors: Chmel Martin , Bartoš Oldřich , Beran Ondřej , Pajer Petr , Dresler Jiří , Čurdová Martina , Holub Michal
Published: June 2021

In our study we present an overview of the use of Oxford Nanopore Technologies (ONT) sequencing technology on the background of Enteric fever. Unlike traditional methods (e.g., qPCR, serological tests), the nanopore sequencing technology enables virtually real-time data generation and highly accurate pathogen identification and characterization. Blood cultures were obtained from a 48-year-old female patient suffering from a high fever, headache and diarrhea. Nevertheless, both the initial serological tests and stool culture appeared to be negative. Therefore, the bacterial isolate from blood culture was used for nanopore sequencing (ONT). This technique in combination with subsequent bioinformatic analyses allowed for prompt identification of the disease-causative agent as Salmonella enterica subsp. enterica serovar Paratyphi A. The National Reference Laboratory for Salmonella (NIPH) independently reported this isolate also as serovar Paratyphi A on the basis of results of biochemical and agglutination tests. Therefore, our results are in concordance with certified standards. Furthermore, the data enabled us to assess some basic questions concerning the comparative genomics, i.e., to describe whether the isolated strain differs from the formerly published ones or not. Quite surprisingly, these results indicate that we have detected a novel and so far, unknown variety of this bacteria.
Sara Andersson, Läsande flickor: Läspolitik och det genomlysta subjektet
Authors: Almqvist Louise
Published: June 2021

Review/Recension
Justyna Deszcz-Tryhubczak & Irena Barbara Kalla (red.), Rulers of Literary Playgrounds: Politics of Intergenerational Play in Children’s Literature
Authors: Geybels Lindsey
Published: June 2021

Review/Recension
Gwen Athene Tarbox, Children's and Young Adult Comics
Authors: Mehrstam Christian
Published: June 2021

Review/Recension
Multiple behavioural risk factors of non-communicable diseases among adolescents in four Caribbean countries: prevalence and correlates
Authors: Pengpid Supa , Peltzer Karl
Published: June 2021

Objectives

The study assessed the prevalence and associated factors of behavioural risk factors of non-communicable diseases (NCDs) among adolescents in four Caribbean countries.

Content

In all 9,143 adolescents (15 years = median age) participated in the cross-sectional “2016 Dominican Republic, 2016 Suriname, 2017 Jamaica, and 2017 Trinidad and Tobago Global School-Based Student Health Survey (GSHS)”. Eight behavioural risk factors of NCDs were assessed by a self-administered questionnaire.

Prevalence of each behavioural NCD risk factor was physical inactivity (84.2%), inadequate fruit and vegetable intake (82.2%), leisure-time sedentary behaviour (49.6%), daily ≥2 soft drinks intake (46.8%), ever drunk (28.6%), twice or more days a week fast food consumption (27.6%), having overweight/obesity (27.4%), and current tobacco use (13.8%). Students had on average 3.6 (SD=1.4), and 79.0% had 3–8 behavioural NCD risk factors. In multivariable linear regression, psychological distress and older age increased the odds, and attending school and parental support decreased the odds of multiple behavioural NCD risk factors.

Outlook

A high prevalence and co-occurrence of behavioural risk factors of NCDs was discovered and several factors independently contributing to multiple behavioural NCD risk factors were identified.
Effects of composition, temperature and shear rate on chocolate milk rheology: an empirical modeling approach incorporating yield behavior
Authors: Qaiser Asif A. , Nazar Rabia , Anjum Mehroz , Saeed Anem , Zeeshan Muhmmad , Tahir Basil , Muzaffar Muhammad , Jameel Naima
Published: June 2021

This study elucidates the effects of composition and temperature on the rheological behavior of chocolate milk formulation. The fat [0.5, 1 and 1.5 g] and xanthan gum contents [0.05, 0.1 and 0.15 g] varied and shear stress-strain rate data were recorded at varying temperature [21.4, 65 and 80 °C]. All compositions showed predominantly a pseudoplastic behavior [i.e., pseudoplasticity index, n < 1] with a strong influence on composition and temperature. Three semi-empirical rheological models, i.e. Power-law, Herschel–Bulkely, and Casson models were fitted on the data using an in-house developed computer program for the best statistical fit. The pseudoplasticity index [n] varied with the composition that initially decreased with temperature and subsequently increased. The other model parameters such as consistency index [k], Casson and Herschel–Bulkely yield stress, and Casson viscosity [at a specified rate i.e., 34.7 s−1] were computed through model fitting and correlated to the microstructural changes inside the fluid keeping in view the composition and temperature. This study helps in correlating chocolate milk processing and quality control based on complex microstructure to the rheological parameters measured at simulated temperatures and shear rates.
Microstructure and elevated temperature mechanical properties of Mg-6Gd-3Y-0.5Zr alloy cast by PEP–SET sand mold
Authors: Huang Y. J. , Wang Y. F. , Zhang S. Y. , Zhang G. L. , Cao F. Y. , Sun J. F. , Ning Z. L.
Published: June 2021

The present work cast a complex Mg-6Gd-3Y-0.5Zr alloy component in a polybenzylic ether phenolic resin (PEP-SET) sand mold using by differential pressure casting. Microstructural characterization was carried out on the castings in the states of as-cast, solution treatment and aging treatment. Their mechanical properties were examined at elevated temperatures. The studied Mg alloy showed noticeably high tensile strengths up to 473 K, followed by a significant decrease with further increasing the testing temperatures. Its mechanical properties at elevated temperatures were compared with those of WE43 alloy fabricated under identical casting conditions.
Historische Text- und Diskurssemantik: Perspektivierungen
Authors: Bär Jochen A.
Published: June 2021

Der Beitrag bietet, anstelle eines Vorwortes, einen Blick auf theoretisch-methodologische Ansätze und (offene) Fragen der historischen Text- und Diskurssemantik. Fokussiert werden insbesondere Konzepte einer ‚reichen‘ und ‚flächigen‘ Semantik sowie zwei unterschiedliche Ausprägungen des Konstruktivismus. Am Schluss steht ein Blick auf Möglichkeiten und Probleme einer diskurs­spezifischen Sprachgeschichte.
Religion and language preservation: the case of Sora
Authors: Krylova Anastasia , Renkovskaya Evgeniya
Published: June 2021

The article, based on field data collected by the authors, analyzes the modern sociolinguistic situation of the Sora language (South Munda languages, Odisha, India) in various religious communities. The religious communities such as Baptists, Catholics, Vishwa-Hindus, Animists, Mattar Banom and Alekh are analyzed. The data on the use of various languages in the religious practices of these communities is considered, accompanied by rich illustrative material. According to the findings of the authors, the preservation of Sora is most successful in the Baptist and Mattar Banom communities.
Self-assembled metal-oxide nanoparticles on GaAs: infrared absorption enabled by localized surface plasmons
Authors: Martínez Castellano Eduardo , Tamayo-Arriola Julen , Montes Bajo Miguel , Gonzalo Alicia , Stanojević Lazar , Ulloa Jose María , Klymov Oleksii , Yeste Javier , Agouram Said , Muñoz Elías , Muñoz-Sanjosé Vicente , Hierro Adrian
Published: June 2021

Metal-oxides hold promise as superior plasmonic materials in the mid-infrared compared to metals, although their integration over established material technologies still remains challenging. We demonstrate localized surface plasmons in self-assembled, hemispherical CdZnO metal-oxide nanoparticles on GaAs, as a route to enhance the absorption in mid-infrared photodetectors. In this system, two localized surface plasmon modes are identified at 5.3 and 2.7 μm, which yield an enhancement of the light intensity in the underlying GaAs. In the case of the long-wavelength mode the enhancement is as large as 100 near the interface, and persists at depths down to 50 nm. We show numerically that both modes can be coupled to infrared intersubband transitions in GaAs-based multiple quantum wells, yielding an absorbed power gain as high as 5.5, and allowing light absorption at normal incidence. Experimentally, we demonstrate this coupling in a nanoparticle/multiple quantum well structure, where under p-polarization the intersubband absorption is enhanced by a factor of 2.5 and is still observed under s-polarization, forbidden by the usual absorption selection rules. Thus, the integration of CdZnO on GaAs can help improve the figures of merit of quantum well infrared photodetectors, concept that can be extended to other midinfrared detector technologies.
Xanthate-modified nanoTiO2 as a novel vulcanization accelerator enhancing mechanical and antibacterial properties of natural rubber
Authors: Liu Yu , Wang Heliang , Guo Xiwei , Yi Mingyuan , Wan Lihong , Liao Shuangquan , Wang Zhifen , Fang Lin
Published: June 2021

With the emerging of sustainability, the fabrication of effective and eco-friendly agents for rubber industry has attracted extensive attention. In this study, a novel and nontoxic titanium dioxide-based vulcanization accelerator (xanthate-modified nanotitanium dioxide (TDSX)) with excellent antibacterial performance, for the first time, was synthesized under the catalyst of ceric ammonium nitrate. Notably, the thermal stability of xanthate was greatly enhanced after being grafted on titanium dioxide (TiO2) nanoparticles, in which the activation energy was increased from 6.4 to 92.5 kJ/mol, enabling the obtained TDSX with multiple functions, mainly consisting of fabulous vulcanization-promoting effects, reinforcing effects, antibacterial properties, and anti-ultraviolet aging effects for natural rubber (NR). Simultaneously, the TDSX can be effectively and uniformly dispersed in the rubber matrix along with the developed interface interaction between TDSX particles and rubber matrix. Compared to the traditional accelerators 2-mercaptobenzothiazole (M) system, the tensile strength and the tearing strength of NR/TDSX was improved by 26.3 and 40.4%, respectively. Potentially, our work for preparing green vulcanization accelerator can provide a new design strategy for multifunctional high performance elastomer materials.
Study of the influence of autoclave sterilization on the properties of citrate functionalized iron oxide nanoparticles
Authors: Girardet Thomas , Cherraj Amel , Pinzano Astrid , Henrionnet Christel , Cleymand Franck , Fleutot Solenne
Published: June 2021

Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are widely used in various areas of the biomedical field: for diagnosis (Magnetic Resonance Imaging), for therapeutic applications (hyperthermia, nanovectorization). These applications require a good stability in water and no aggregation of SPIONs, with well-controlled physicochemical and magnetic properties. In this work, SPIONs functionalized by citrate ligands are synthesized in a one-step process with the aim of producing stable water-dispersible nanoparticles with a well-crystallized spinel structure. Microwave technology is implemented to achieve this objective given the ease, speed and reproducibility of the method. For their future use in biomedical applications, the sterilization of these SPIONs are essential by an autoclave treatment. The influence of this treatment on the physicochemical and magnetic properties of the SPIONs is determined by a systematic characterization before and after sterilization by Transmission Electronic Microscopy, Dynamic Light Scattering, X-ray Diffraction, Fourier Transformed Infra-Red, ThermoGravimetric Analysis and magnetic measurements.
Enhanced recovery after surgery (ERAS) in cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC): a cross-sectional survey
Authors: Bhandoria Geetu , Solanki Sohan Lal , Bhavsar Mrugank , Balakrishnan Kalpana , Bapuji Cherukuri , Bhorkar Nitin , Bhandarkar Prashant , Bhosale Sameer , Divatia Jigeeshu V. , Ghosh Anik , Mahajan Vikas , Peedicayil Abraham , Nath Praveen , Sinukumar Snita , Thambudorai Robin , Seshadri Ramakrishnan Ayloor , Bhatt Aditi
Published: June 2021

Objectives

Enhanced recovery after surgery (ERAS) protocols have been questioned in patients undergoing cytoreductive surgery (CRS) with/without hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal malignancies. This survey was performed to study clinicians’ practice about ERAS in patients undergoing CRS-HIPEC.

Methods

An online survey, comprising 76 questions on elements of prehabilitation (n=11), preoperative (n=8), intraoperative (n=16) and postoperative (n=32) management, was conducted. The respondents included surgeons, anesthesiologists, and critical care specialists.

Results

The response rate was 66% (136/206 clinicians contacted). Ninety-one percent of respondents reported implementing ERAS practices. There was encouraging adherence to implement the prehabilitation (76–95%), preoperative (50–94%), and intraoperative (55–90%) ERAS practices. Mechanical bowel preparation was being used by 84.5%. Intra-abdominal drains usage was 94.7%, intercostal drains by 77.9% respondents. Nasogastric drainage was used by 84% of practitioners. The average hospital stay was 10 days as reported by 50% of respondents. A working protocol and ERAS checklist have been designed, based on the results of our study, following recent ERAS-CRS-HIPEC guidelines. This protocol will be prospectively validated.

Conclusions

Most respondents were implementing ERAS practices for patients undergoing CRS-HIPEC, though as an extrapolation of colorectal and gynecological guidelines. The adoption of postoperative practices was relatively low compared to other perioperative practices.
Cyclone pressure drop reduction and its effect on gas–particle separation capability: principle, performance, and assessment
Authors: Zhao Bingtao , Qian Weifeng , Li Huimei , Su Yaxin
Published: June 2021

Cyclone separators have been widely used for gas–particle separation in chemical engineering. However, their enhancement in separation performances usually increases the pressure drop, which inevitably leads to an increase in operating energy consumption. One of the challenging issues is how to reduce the cyclone pressure drop while improving separation performances. To gain insight into the pathways and impacts of cyclone pressure drop reduction, this work reviews the state-of-the-art technical principles, performances and effects, focusing on the processes, mechanisms, and characteristics of pressure drop reduction by inlet/outlet variations, additional auxiliary devices, local cyclone dimension improvement, and global optimization based on intelligent algorithms. The cyclone performances are assessed using a proposed index that combines the Euler number and the square-root particle cut-off Stokes number. It is suggested that the pressure drop and separation capability usually have a dynamic compromise. Considering the comprehensive performances, the technology using helical roof inlet, cross cone, increasing cylindrical height with h/D = 4.3 (H/D = 6.35), and globally optimized design by Sun et al. (2017) are respectively considered to the others. Particularly, the last one is recommended to be more representative in practice. Finally, the key issues to be considered in further research were also prospected.
A new N-oxide benzylisoquinoline alkaloid isolated from the leaves of atemoya (Annona cherimola × Annona squamosa)
Authors: Rabêlo Suzana V. , Araújo Edigênia C. C. , Costa Emmanoel V. , Braz-Filho Raimundo , Barison Andersson , Santos Maria de F. C. , Oliveira Gibson G. , Tomaz José C. , Rolim Larissa A. , Lopes Norberto P. , Silva Maria F. S. , Moraes Manoel O. , Pessoa Cláudia do Ó , El Aouad Noureddine , Almeida Jackson R. G. S.
Published: June 2021

Phytochemical investigation of the atemoya aerial parts was carried out by LC-MS-IT and cytotoxic activities were evaluated as well. These results led to the identification of a new N-oxide alkaloid (dehydroanomuricine-N-oxide) and eight other alkaloids: scoulerine, reticuline, isocorydine, norisocorydine, asimilobine, nornuciferine, anonaine, and liriodenine. The new alkaloid dehydroanomuricine-N-oxide and anomuricine were also isolated. The structures of these compounds were determined by spectroscopic and spectrometric techniques. The cytotoxic capacity of crude methanolic extract and the alkaloidal fraction were evaluated, showing moderate cytotoxicity. The isolation and identification of these alkaloids are an important contribution to the chemotaxonomy of the genus Annona and the Annonaceae family.
Antimicrobial synergism and antibiofilm activities of Pelargonium graveolens, Rosemary officinalis, and Mentha piperita essential oils against extreme drug-resistant Acinetobacter baumannii clinical isolates
Authors: Kafa Ayse Humeyra Taskin , Aslan Rukiye , Celik Cem , Hasbek Mursit
Published: June 2021

Rosemary officinalis L., Pelargonium graveolens L., and Mentha piperita L., essential oils are used by complementary medicine specialists simultaneously with traditional antibiotics for treatment purposes. The chemical composition of essential oils was analyzed by the gas chromatography-mass spectrometry method. In vitro antibacterial and antibiofilm activities of the essential oils were tested against extreme drug-resistant (XDR) colistin-resistant and colistin susceptible Acinetobacter baumannii clinical strains. The synergistic activities between essential oils and colistin antibiotics were investigated by the checkerboard method. The highest antibacterial effect was detected in mint essential oil (2.5–5 μl/ml), followed by pelargonium essential oil (5–20 μl/ml) and rosemary essential oil (5–20 μl/ml). The combination of rosemary essential oil or pelargonium essential oil with colistin showed strong synergistic activity in most of the bacterial strains tested (fractional inhibitory concentration index ≤ 0.5; synergy). As a result of the combination of mint essential oil and colistin, an indifferent effect was observed in only two bacterial strains, and other strains could not be evaluated. No antagonistic effects were observed in any of the tested essential oils. As a result of the effectiveness of the combination, the minimum inhibitory concentration (MIC) values of colistin in XDR-A. baumannii clinical isolates decreased 2–32 fold. Additionally, the sub-MIC concentration of essential oils exhibited an inhibitory effect (48–90%) against the biofilm layer of tested A. baumannii strains.
Quintic B-spline collocation method for numerical solution of free vibration of tapered Euler-Bernoulli beam on variable Winkler foundation
Authors: Ghannadiasl Amin
Published: June 2021

The collocation method is the method for the numerical solution of integral equations and partial and ordinary diﬀerential equations. The main idea of this method is to choose a number of points in the domain and a ﬁnite-dimensional space of candidate solutions. So, that solution satisﬁes the governing equation at the collocation points. The current paper involves developing, and a comprehensive, step-by step procedure for applying the collocation method to the numerical solution of free vibration of tapered Euler-Bernoulli beam. In this stusy, it is assumed the beam rested on variable Winkler foundation. The simplicity of this approximation method makes it an ideal candidate for computer implementation. Finally, the numerical examples are introduced to show eﬃciency and applicability of quintic B-spline collocation method. Numerical results are demonstrated that quintic B-spline collocation method is very competitive for numerical solution of frequency analysis of tapered beam on variable elastic foundation.
Experimental study of low Reynolds number effects on aerodynamics of smooth and sinusoidal leading-edge wings in the vicinity of the ground
Authors: Mehraban A. A. , Djavareshkian Mohammad Hassan
Published: June 2021

Present study experimentally investigates the effects of ground clearance and Reynolds number on aerodynamic coefficients of smooth and sinusoidal leading-edge wings. Wind tunnel tests are conducted over a wide range of angles of attack from zero to 36 degrees, low Reynolds numbers of 30,000, 45,000 and 60,000, and also ground clearances of 0.5, 1 and ∞. Results showed that reduction of ground clearance and increment of Reynolds number cause the lift coefficient and the lift to drag ratio of both wings to be enhanced. Furthermore, the effects of Reynolds number and ground clearance on the smooth leading-edge wing are more than the sinusoidal leading-edge one. In addition, the sinusoidal leading-edge wing shows an excellent performance in the poststall region due to producing a higher lift and also by delaying the stall angle compared to the smooth leading-edge wing.
La política de cuerpos académicos en una universidad pública
Authors: Hernández Hernández Felipe
Published: June 2021

Este artículo analiza el Programa para el Desarrollo Profesional Docente (Prodep) que impulsa la investigación en educación superior en México, con base en los grupos de investigación denominados cuerpos académicos (CA). El estudio examina el impacto de esta política educativa de formación y consolidación de CA en el periodo 1996-2019 en la Universidad Autónoma de Tlaxcala, que es de carácter estatal. El objetivo es valorar el impulso a la investigación mediante la formación de investigadores en los CA conforme a lo dispuesto por el Prodep. El enfoque metodológico es mixto. Emplea el método de análisis de contenido que incluyó un estudio ideológico y otro reflexivo, y un análisis de antes-después y el uso del enfoque top down de Sabatier. Los resultados muestran en el lapso de 25 años que, a pesar del tiempo que tardó el Prodep en asentarse en la comunidad académica de esta universidad, ha tenido un impacto positivo, estimulando la formación y el desarrollo de los CA y mejorando los niveles de competitividad y habilitación académica de sus profesores. Es necesaria la implementación de políticas institucionales consistentes y duraderas para que, junto con las políticas nacionales, se logre el propósito de consolidar la investigación en las universidades.
Microdiamonds from the Zeleny Yar Neogene Placer (the Ros'-Tikych Megablock of the Ukrainian Shield)
Authors: KVASNYTSYA V.M.
Published: June 2021

We studied a collection of microdiamonds from the Zeleny Yar Neogene placer on the Ros’-Tikych megablock of the Ukrainian Shield, which consists of 102 microdiamonds, with crystal sizes 0.2-0.5 mm, using crystal morphology, photoluminescence, infrared and Raman spectroscopy, isotopic composition of carbon and helium of microdiamonds. Crystal forms are dominantly octahedra, others are cubes, combinational crystals {111}+{110}+{100}, cube-octahedra, and transitional forms {111}+{110}; rhombic dodecahedrons are rare. Many microdiamonds are damaged crystals and their fragments. Up to 20% of the studied microdiamonds are yellow, green, pink-purple, brown, gray, and black. The most colored crystals are among the cubes. Up to 70% of the studied microdiamonds are blue, green, yellow and orange in ultraviolet light. Many of the microdiamonds, especially cubes and crystals of the combinational form {111}+{110}+{100}, have an orange photoluminescence (center at 575 nm). 50% of the crystals are nitrogen-free crystals of type IIa. Nitrogen crystals of type Ia amount to 45% (among them 29 % of subtype IaA, 11% of subtype IaAB and 5% of subtype Iab) and 5% of type Ib. The content of nitrogen ranges from 57 to 612 at. ppm with an average nitrogen content of 224 at. ppm. The centers B2 (lines 1358-1380 cm–1) and hydrogen centers (3107 cm–1, 1405 cm–1) were recorded in IR spectra of some microdiamonds. The Raman line ranges from 1331.25 cm–1 to 1331.75 cm–1 with FWHM from 2.04 cm–1 to 4.47 cm–1. The carbon isotopic composition of microdiamonds shows a very wide range from –26.74 to –3.55‰ δ13C PDB. The content of helium isotopes for the studied crystal is 73.42 × 10–12 cm3/g of 3He and 0.265 × 10–6 cm3/g of 4He. Given the wide range of values of the isotopic composition of carbon δ13C, relatively high nitrogen content and cubic form of many crystals, it is possible to predict the eclogite association as the mantle crystallization medium of the Zeleny Yar microdiamonds. The location of the parent rocks of the microdiamonds is assumed to be the Berdychiv uplift of the Podolia block of the Ukrainian Shield.
Genesis of Graphite in Metapelites in the North-Western Border of the Lypniazhka Massif (the Inhul Domain of the Ukrainian Shield)
Authors: LYZHACHENKО N.M. , KURYLО S.I. , BONDARENKO S.M. , MILOVSKY R. , MILOVSKA S.
Published: June 2021

This study presents results of an investigation of metamorphic rocks of the Inhul-Inhulets series located in the northwestern border of the Lypniazhka granite-migmatite massif (Inhul domain, the Ukrainian Shield). The rocks were studied petrographically and mineralogically and carbon isotope, Raman spectroscopic and microprobe measurements were made. Graphite and calcite were given special attention. Metapelites and quartz-rich graphite-biotite-garnet rocks were investigated. The former consist of biotite, graphite-biotite, amphibole-bearing graphite-biotite gneisses. Graphite in them is evenly distributed through the rock groundmass. The δС13 values of graphite lie between -39.4‰ and -33.6‰ (relative to PDB). The graphite is considered to be of biogenic origin. Quartz-rich graphite-biotite-garnet rocks are less common, but they also contain graphite. The latter occurs as inclusions in the major minerals either forming clusters. Its δС13 values fall between -28.45‰ and -22.2‰ (relative to PDB). Based on the Raman spectra, carbon from the gneisses has an ordered graphite structure. The temperature of graphite crystallization was estimated to be between 554 and 630°С and corresponds to the amphibolite facies.
МОДЕЛИРОВАНИЕ УСТАНОВИВШЕГОСЯ ДВИЖЕНИЯ НАГРУЗКИ ПО ОРТОТРОПНОЙ ПЛАСТИНЕ НА ВИНКЛЕРОВСКОМ ОСНОВАНИИ
Authors: Heraskin B.D. , Hodes Yu. Ya. , Kochetkova I.B.
Published: June 2021

Рассмотрена динамическая задача об установившемся движении нагрузки по бесконечной упругой ортотропной пластине, лежащей на основании Винклера. Для определения поля прогибов использован метод интегрального преобразования Фурье. В результате анализа сходимости интеграла, выражающего прогибы, установлен диапазон скоростей движения нагрузки, при которых реализуется установившийся процесс деформирования.
FORCED VIBRATIONS OF A INHOMOGENEOUS ORTHOTROPIC CYLINDRICAL SHELL STIFFENED WITH A CROSS-SYSTEM OF RIBS IN LIQUID
Authors: Ismayilov H.K.
Published: June 2021

In the paper we study forced vibrations of an orthotropic cylindrical shell inhomogeneous in thickness and stiffened with a cross-system of ribs in liquid under the action of inner radial pressure pulsating in time. Based on Hamilton – Ostrogradsky variational principle, we construct a system of equations to determine the displacements of the mid-surface points of an orthotropic cylindrical shell inhomogeneous in thickness and stiffened with a cross-system of ribs under dynamical interaction with liquid. Surface loads acting on the cylindrical shell inhomogeneous in thickness and stiffened with a cross-system of ribs as viewed from liquid are determined from the solutions of liquid motion equations written in potentials. Analytic formulas for finding the displacements of the midsurface points of a liquid-contacting orthotropic cylindrical shell inhomogeneous in thickness and stiffened with a cross-system of ribs, were obtained.
Georgian experience in the field of education and cultural policy: the example of the first democratic republic of Georgia in the years 1918 -1921
Authors: Darchashvili Manana
Published: June 2021

Aim. The paper aims to study and present the issue of Georgian education,   analyze it chronologically and thematically based on past experience. The paper deals with the period of the First Republic of Georgia, 1918-1921, and highlights the place of education and culture in Georgian politics. Moreover, the paper is focused on the connections of modern Georgian politics and the centuries-old traditional heritage and its transformation into the present reality.

Method. The paper is presented based on a number of researched documents, empirical material, scientific research papers, monographs, analysis of government documents, historical-comparative method.

            Result. The paper presents the reality of the first democratic republic in Georgia in 1918-1921, the effective steps of the state for the development of proper education and cultural policy, and its introduction and development in practice.

            Conclusion. Several empirical materials prove that during the period of the First Republic of Georgia (1918-1921), despite the difficult political situation in Georgia, education in Georgia, with the support of the government and due to the active and creative work of representatives of such field as education, literature, theater, music, cinema, and science. were well developed. This issue is part of the country's internal policy, which is important and relevant today.
Luteolin, an aryl hydrocarbon receptor antagonist, alleviates diabetic retinopathy by regulating the NLRP/NOX4 signalling pathway: Experimental and molecular docking study
Authors: Yang Y. , Zhou M. , Liu H.
Published: June 2021

Objective

The present report evaluates the protective effects of luteolin against diabetic retinopathy (DR).

Materials and methods

Diabetes was induced in rats by i.p. administration of 60 mg/kg of streptozotocin (STZ), followed by treatment with luteolin for 4 weeks. The effects of luteolin were determined based on the blood glucose and cytokine levels, and parameters of oxidative stress in retinal tissue of DR rats. The diameter of retinal vessels was estimated by fundus photography. A Western blot assay was used to determine the expression of apoptotic proteins and Nod-like receptor 3 (NLRP3) pathway proteins in the retina of DR rats. A molecular docking study was performed to evaluate the interaction between luteolin and NLRP3.

Results

The level of blood glucose was reduced in the luteolin-treated group compared with the DR group. Reductions in cytokines and oxidative stress were observed in the retinal tissues of the luteolin-treated group relative to the DR group. Moreover, treatment with luteolin reduced the expression of NLRP1, NOX4, TXNIP, and NLRP3 proteins, and ameliorated the altered expression of apoptotic proteins in the retina of DR rats.

Conclusion

In conclusion, luteolin prevents retinal apoptosis in DR rats by regulating the NLRP/NOX4 signalling pathway.
Long Short-Term Memory Approach for Predicting Air Temperature In Indonesia
Authors: Gunawan Putu Harry , Munandar Devi , Farabiba Anis Zainia
Published: June 2021

Air temperature is one of the main factors for describing the weather behaviour in the earth. Since Indonesia is located on and near equator, then monitoring the air temperature is needed to determine either global climate change occurs or not. Climate change can have an impact on biological growth in various fields. For instance, climate change can affect the quality of production and growth of animal and plants. Therefore, air temperature prediction is important to meteorologists and Indonesian government to provide information in many sectors. Various prediction algorithms have been used to predict temperature and produce different accuracy. In this study, the deep learning method with Long Short-Term Memory (LSTM) model is used to predict air temperature. Here, the results show that LSTM model with one layer and Adaptive Moment Estimation (ADAM) optimizer produce accuracy which is 32% of , 0.068 of MAE and 0.99 of RMSE. Moreover, here, ADAM optimizer is found better than Stochastic Gradient Descent (SGD) optimizer.
El periodismo político de Galdós durante el Sexenio Revolucionario
Authors: Vilches-García Jorge
Published: June 2021

La imagen del Galdós republicano con simpatías socialistas no corresponde con las ideas políticas que defendió en la prensa durante el Sexenio revolucionario. En las crónicas parlamentarias que escribió para Las Cortes se mostró monárquico demócrata, fue liberal conservador en la Revista de España y El Debate, y cínico en La Ilustración de Madrid. Al tiempo, dependiendo del medio para el que escribiera, era despiadado con republicanos, socialistas, radicales y carlistas. El advenimiento de la República lo consideraba una desgracia para España, al mismo nivel que el triunfo del carlismo. Galdós ocultó en su vejez las cabeceras para las que escribió. Es posible que fuera para no perjudicar su imagen final de republicano coherente.
La enseñanza de primeras letras en el Colegio de La Pureza: una primera aproximación a la labor literaria de Alberta Giménez
Authors: Ballester-Morell Blanca
Published: June 2021

Este trabajo se adentra en las circunstancias ―vitales y pedagógicas― que animaron la labor literaria de Alberta Giménez Adrover y abre una vía de investigación encaminada a analizar la producción poética y dramática de una de las voces más destacadas de la educación en Baleares. Asimismo, este primer acercamiento a su obra busca reseñar algunas de las funciones que tanto lo poético como lo teatral cumplieron en su actividad docente al frente del colegio de La Pureza y de la Escuela Normal de Maestras de Palma. Para ello, la documentación aportada por sus principales biógrafos ha resultado de especial ayuda, sobre todo los testimonios y documentos acopiados por Margarita Juan. La escritura literaria, en el caso de Alberta Giménez, no puede entenderse únicamente como inclinación creativa fruto de la necesidad individual, esta constituye un ejercicio fundamental del programa pedagógico y de la educación integral promovida desde el colegio de La Pureza.