bluuebunny/crossref_metadata_2025 huggingface dataset:
Targeted gene sequencing panels: applicability for neoantigen profiling of colon and rectal adenocarcinoma
Authors: Kanygina A.V. , Sharova E.I. , Sultanov R.I. , Schelygin Y.A. , Doludin Y.V. , Kostryukova E.S. , Generozov E.V.
Published: December 2018

Cancer immunotherapy represents a promising and rapidly developing approach for the treatment of oncological diseases. Among the methods of personalized adjuvant immunotherapy, neoantigenic peptide-based drugs have demonstrated substantial efficiency. These drugs are designed to target mutant proteins arising from somatic alterations in the genome of tumor cells and thus stimulate immune response against tumor tissues. The methods of individual screening for potentially immunogenic mutations are mostly based on next-generation exome sequencing of tumor samples, which is a complex and costly procedure for clinical application. Targeted gene sequencing panels limited to a certain set of genes represent a reasonable alternative to WES. Targeted sequencing is also more efficient when there is a low amount of the sample DNA available. We have estimated the potential efficiency of targeted oncological panels in terms of somatic neoantigen profiling in colorectal cancer (colon and rectal adenocarcinoma). The clinical practice of identification of frequent somatic variants does not provide enough data for designing an efficient personalized drug when applied to low and medium mutated cancers such as colorectal cancer. Our analysis of 11 commercially available panels containing different number of genes has shown that neither the larger size of a panel nor its initial customization for colorectal cancer provides a significantly better estimation of an individual somatic mutation profile. The optimal approach is to use the general-purpose medium-sized cancer panels (2300-11200 amplicons and/or 150-600 genes). These panels allow to detect a sufficient number of immunogenic epitopes (>3) per patient for over 30-50% of patients.
Anatomical and clinical evaluation of perforator-based flaps of lower limb
Authors: Jain Mohit , Basant R. K. , Madeshiya Shivam , Kumar D. , Dwivedi Vikas , Rai Nandan
Published: December 2018

Background: Wound of lower leg have a poor and delayed healing due to paucity of blood supply. Coverage of defects of leg and foot has always posed a problem for reconstructive surgeon. The objective of this study was to evaluate anatomical basis of various perforator-based flaps in lower limb and their clinical outcome and usefulness.Methods: All patients with post traumatic defects with exposed bones/tendons in the leg and ankle region presenting in MLN Medical college, Allahabad from August 2011 to July 2012 were included in the study.Results: A total 12 patients were included in study. Majority of cases are of compound fracture following accidents involving lower one third of leg. Majority of flaps were based on peroneal artery (5) and posterior tibial artery (5), only 2 flaps were based on anterior tibial artery. Maximum flap length was 21cm and maximum flap rotation was 180º. Complications occurred more in cases having maximum rotation. Result were good in 11 patients and satisfactory in 1 patient with coverage of the defect leading to healing of the wound. More time gap between injury and flap reconstruction leads to more complications and longer hospital stay. Graft site complication occur in 5 cases include partial flap necrosis, infection and venous congestion. There was no complication at the donor site.Conclusions: Perforator based flaps can be used for all large lower leg defects provided there is correct measurement and anatomical knowledge of various perforators, with good functional and cosmetic results.
Efficacy of early thoracoscopic debridement for syn-pneumonic pleural effusions in pediatric age group
Authors: Grandhi Kiran , Kokiwar Prashant
Published: December 2018

Background: Pleural effusion can be treated by antibiotics alone but thoracoscopy assisted debridement has proved superior to antibiotics alone. There is need to study this aspect in more details related to the superiority of the treatment. The objective was to study efficacy of early thoracoscopic debridement for syn-pneumonic pleural effusions in pediatric age group.Methods: A hospital based follow up study was carried out among 40 children of 1-7years of age. They were divided into two groups. One group with 15 children received only antibiotics while the other group with 25 children received thoracoscopic debridement. The results were compared in terms of hospital stay and clinical outcome.Results: It was found that the hospital stay was significantly shorter in children who received thoracoscopic debridement compared to antibiotic group. The chest X-ray was normal in all cases who received thoracoscopic debridement compared to antibiotic group. Decortications were required in five children in antibiotic group compared to none who received thoracoscopic debridement. There was no morbidity and mortality in the children received thoracoscopic debridement. Clinical and symptomatic relief was much better in children received thoracoscopic debridement compared to antibiotic group where there was persistence of the symptoms.Conclusions: Thoracoscopy done in 3days of syn-pneumonic effusions give better out come in terms of hospital stay, morbidity, radiological resolution, compared to thoracocentesis done cases.
A prospective study of neglected and resistant clubfoot cases treated using Joshi’s external stabilization system
Authors: Gupta Rajat , Kumar Krishan , Jugran Panshul
Published: December 2018

Background: Clubfoot is a common congenital deformity occurring in 1 to 2 per thousand live births. In relapsed or neglected clubfoot the deformities become fixed and treatment using conservative methods often fails. JESS (Joshi’s external stabilizing system) is a simple construct for the correction of deformity in these patients. The present study was taken up to assess the results of JESS fixator in correction of deformities in neglected, resistant or relapsed cases of clubfoot and deformities in the late presented patients.

Methods: The present study was conducted on randomly selected patients of clubfoot in the department of Orthopaedics, ESI Hospital, Basaidarapur, New Delhi between June 2014 and December 2017. A total of 22 feet (of 16 patients) suffering from neglected, resistant or relapsed clubfoot under the age of 7 years, were included in the study.

Results: Excellent results were obtained in 52% of cases, while 19% had good, 14.5% had fair and 14.5% had poor results. Complications encountered were temporary oedema in 10 feet, superficial pin tract infection in 5 feet, pin loosening in 3 feet, skin necrosis 2 feet and flexion contracture of toes in 2.

Conclusions: JESS application is an excellent technique for treatment of recurrent and neglected clubfoot. This procedure is ideally suited for children in whom the clubfoot deformities remain uncorrected by POP casts and manipulation, as well as for recurrent clubfoot cases.
Serum 25-hydroxyvitamin D level in psoriasis patients: a case-control study
Authors: Gupta Surinder , Garg Preeti , Gupta Nakul
Published: December 2018

Background: Sufficient level of vitamin D in blood is required for proper regulation of cell differentiation and proliferation. Unchecked proliferation of cells leads to various disease states. Vitamin D also has immunomodulatory effects in the body. Psoriasis is a chronic inflammatory and hyperproliferative disease with vitamin D having an impact on it. This case – control study was done to judge the levels of vitamin D in patients of psoriasis compared to age and sex matched controls.

Methods: A case control study was conducted including 50 patients (35 females and 15 males) of chronic plaque psoriasis from dermatology outpatient department of Maharaja Agrasen Medical College (MAMC), Agroha, Haryana, representing patients from north India and 50 healthy controls. Both urban and rural background patients were included.

Results: The mean serum 25-hydroxyvitamin D (25-OHD) level in psoriasis patients was 22.865±11.386 ng/ml, whereas in controls it was 35.116±11.048 ng/ml (p<0.001). Serum level of 25-OHD in psoriatic patients was deficient (<20 ng/ml) in 26 (52%), insufficient (20-30 ng/ml) in 8 (16%) psoriatic patients.

Conclusions: High prevalence of low vitamin D level was found in this study. We infer that vitamin D does play a role in the pathogenesis, precipitation, exacerbation, or treatment resistance of psoriasis.

 
AS NARRATIVAS COMO UMA POSSIBILIDADE PARA O PROCESSO DE ENSINO E APRENDIZAGEM EM CONTEXTO INTERCULTURAL
Authors: Souza Gabriela Barbosa , Bastos Pacheco Lílian Miranda
Published: December 2018

O presente estudo objetiva evidenciar o papel das narrativas como uma possibilidade para o processo de ensino e aprendizagem em contexto intercultural. Inicialmente apresenta-se o contexto histórico das políticas públicas direcionadas para a educação escolar indígena. Posteriormente, discute-se sobre a função das narrativas para o processo de ensino e aprendizagem em contexto intercultural a partir de depoimentos de membros do povo indígena Pataxó Hãhãhãi. Nessa perspectiva, destaca-se a importância do trabalho pedagógico organizado através dos contos do povo indígena Pataxó Hãhãhãi para o ensino formal nessa comunidade, possibilitando a estes o conhecimento de valores da sua própria cultura, bem como o estudo da estrutura formal da língua, através do ensino/aprendizagem de gêneros e tipologias textuais. Considera-se que o trabalho com gêneros textuais narrativos poderá possibilitar aos professores indígenas melhor mediação entre o trabalho com a língua e os saberes culturais, cotejando os conteúdos universais e a transmissão de narrativas locais.
“COISA DE MENINO, COISA DE MENINA” – O PAPEL DA EDUCAÇÃO FÍSICA NA COMPREENSÃO DAS RELAÇÕES DE GÊNERO COMO BASE PARA UMA EDUCAÇÃO INCLUSIVA
Authors: Carballo Fábio Peron , Fonseca A. P. M. , Ferreira P. S. S. , Neto J. A. R.
Published: December 2018

A revisão da literatura aponta que a sexualidade é entendida como algo inerente, sendo constituída ao longo da vida. Sexo é expressão biológica que define um conjunto de características anatômicas e funcionais (genitais e extragenitais). A construção do que é pertencer a um ou outro sexo, se dá pelo tratamento diferenciado para meninos ou meninas, inclusive nas expressões diretamente ligadas à sexualidade e pelos padrões socialmente estabelecidos. Esses padrões são oriundos das representações sociais e culturais construídas a partir das diferenças biológicas dos sexos e transmitidas pela educação, o que atualmente recebe o nome de relações de gênero. O intuito deste trabalho é averiguar o quanto os alunos são influenciados pelos conceitos culturais que estabelecem o que é adequado em relação ao gênero e se agem em conformidade a eles. Trata-se de uma pesquisa quanti-qualitativa, por meio da aplicação de um questionário a alunos do sétimo ao nono anos de escolas públicas da Cidade de Cláudio. Os resultados apontam que esse tema tem que ser mais debatido e aprofundado em todos os segmentos educacionais. E a Educação Física especificamente deve cumprir um dos objetivos gerais da no ensino fundamental, que por meio de sua práxis deve levar os alunos a participar de atividades corporais, estabelecendo relações equilibradas e construtivas com os outros, reconhecendo e respeitando características físicas e de desempenho de si próprio e dos outros, sem discriminar por características pessoais, físicas, sexuais ou sociais.
Analysis of ALDH1A1 and ALDH1A3 Gene mRNA Expressions in Adipose-Derived Stem Cells (ASCs) and Umbilical Cord Stem Cells (UCSCs)
Authors: Wanandi Septelia Inawati , Purnamawati Purnamawati , Tamara Alice , Putri Karina Teja , Simadibrata Daniel Marcellius
Published: December 2018

BACKGROUND: ALDH1A1 and ALDH1A3, the most renowned isozymes of aldehyde dehydrogenase (ALDH)1, are important in regulating the pluripotency of human mesenchymal stem cells (MSCs) and cancer stem cells (CSCs). The study aimed to analyze the mRNA expression of ALDH1A1 and ALDH1A3 genes in adipose stem cells (ASCs) and umbilical cord stem cells (UCSCs) along with their correlations to Oct-4 mRNA expression. Additionally, the interaction between these proteins was also investigated using in silico study to confirm the pluripotency of both MSCs compared to human breast ALDH+ CSCs.METHODS: This research focused on determining mRNA levels of ALDH1A1, ALDH1A3 and Oct-4 in ASCs and UCSCs using one-step qRT-PCR. The data were then normalized to those in human breast CSCs and 18S rRNA. Oct-4 gene expression was also analyzed to determine the pluripotency of ASCs and UCSCs. The protein-protein interactions were in silico analyzed using String 9.1 software.RESULTS: Relatively, ALDH1A3 was expressed at similar level in ASCs and UCSCs, while ALDH1A1 expression level was significantly higher in ASCs compared to UCSCs. In contrast to ALDH1A3, the expressions of ALDH1A1 in both MSCs were significantly lower than breast CSCs similar to Oct-4 expressions, as also revealed by the in silico data showing the interaction between these proteins. This suggests the role of ALDH1A1 on pluripotency.CONCLUSION: ALDH1A1 and ALDH1A3 were distinctly expressed in UCSCs and ASCs, which might be associated with unique properties of ASCs and UCSCs. This study may contribute to further research in terms of implication of ALDH1A1 and ALDH1A3 expressions towards the properties of MSCs and its application in stem cell therapy.KEYWORDS: ALDH1A1, ALDH1A3, UCSC, ASC, breast ALDH+ CSC, Oct-4
Niños españoles con sintomatología depresiva: un estudio de sus quejas somáticas
Authors: Orgilés Mireia , Fernández-Martínez Iván , Melero Silvia , Morales Alexandra , Espada José P.
Published: December 2018

La presencia de síntomas somáticos en población clínica infantil ha sido analizada en estudios internacionales, pero son escasos los trabajos dirigidos a estudiar las características de los síntomas somáticos en niños españoles con sintomatología depresiva. El presente estudio examina la relación entre las quejas somáticas y los síntomas depresivos en una muestra de niños españoles, teniendo en cuenta su sexo y edad. Participaron 666 niños con edades entre 8 y 12 años que completaron el Inventario de Depresión Infantil y el Inventario de Somatización Infantil que examina 35 síntomas somáticos. Los resultados indican que los síntomas pseudoneurológicos, gastrointestinales y de dolor son más frecuentes en los niños con sintomatología depresiva, siendo el dolor de articulaciones, el dolor de cabeza y el cansancio los síntomas más prevalentes. Se concluye la importancia de atender adecuadamente a los síntomas somáticos puesto que con frecuencia pueden responder a un trastorno emocional más que a una enfermedad física.
ANÁLISIS RETICULAR DE REGISTROS CUALITATIVOS EN INSTITUCIONES TOTALES: EL CASO DEL HOSPITAL NEUROPSIQUIATRICO DR. NÉSTOR M. SEQUEIROS. PROVINCIA DE JUJUY (ARGENTINA).
Authors: Fernández Federico
Published: December 2018

En este trabajo se analizan una serie de registros cualitativos realizados por profesionales residentes de psicología en torno a un taller de fútbol en el que participaron 15 pacientes internados en un Hospital Neuropsiquiatrico. La perspectiva metodológica utilizada para la investigación se basó en un enfoque mixto, usando tanto herramientas métricas propias del análisis formal de redes sociales, como así también técnicas cualitativas como la observación en campo y charlas informales con los pacientes internados. Entre los resultados obtenidos tras la aplicación de este enfoque metodológico, se encuentra el reconocimiento de los vínculos familiares del paciente como un nudo problemático que debe ser contextualizado en la lógica inherente a los internados psiquiátricos, y la predominancia del uso de categorías médicas consignadas en las historias clínicas para describir roles e interacciones de carácter inter-subjetivo entre los pacientes internados.
Co-ocurrencia de distintas violencias en el noviazgo en una muestra de jóvenes mexicanos procedentes de zona rural
Authors: Espinobarros-Nava Fermina , Muñoz-Ponce Norma Nelida , Rojas-Solís Dr. José Luis
Published: December 2018

El estudio de la violencia en parejas jóvenes ha llamado la atención de la comunidad científica en décadas recientes, no obstante, existen nuevos tipos de violencia, así como poblaciones que no son frecuentemente consideradas en las investigaciones. Por ello el objetivo de esta investigación es analizar la prevalencia y co-ocurrencia de violencia off-line (cara a cara) como on-line (a través de medios electrónicos) en relaciones de pareja de jóvenes procedentes de zona rural. Se realizó un estudio desde un enfoque cuantitativo, con un diseño no experimental, transversal y ex post facto. La muestra estuvo constituida por 231 estudiantes pertenecientes a una universidad pública de Guerrero (México) y provenientes de zona rural, de los cuales 86 fueron hombres y 145 mujeres, con edades comprendidas entre los 18 y 27 años; quienes contestaron las escalas Violence in Adolescents Dating Relationships Inventory (VADRI) y el Cyber Dating Abuse Questionnaire (CDAQ). Entre los resultados destaca la existencia de violencia de distintos tipos en hombres y mujeres, una mayor frecuencia en hombres tanto de violencia sufrida como cometida, así como la co-existencia de diferentes tipos de violencia tanto off-line como on-line en ambos sexos.
Bases psicosociales del prejuicio étnico en el Perú: el caso de las categorías afroperuanos, peruanos andinos y peruanos blancos
Authors: Guillén Zambrano Henry Raúl , Cueto Rosa María , Raffo Giácomo Giussepi Olano
Published: December 2018

Tomando como base una muestra de personas de clase media de la ciudad de Lima (n=194) se analiza la relación entre variables ideológicas, emocionales y de contenido estereotípico con la valoración personal y percibida de tres categorías étnico raciales: peruanos andinos, peruanos blancos y afroperuanos. Los resultados permiten visibilizar el papel de las variables ideológicas en los niveles de prejuicio dirigidos a dichas categorías, principalmente a las categorías blanco y afroperuano. Además, se hallaron impactos específicos de dimensiones estereotípicas tradicionalmente asociadas con la categoría blanco, andino y afroperuano, como la competencia, lo moral y lo positivo en términos de calidez, respectivamente. Así también, se identifican impactos específicos de las emociones asociadas a cada categoría, principalmente a la categoría peruano blanco y peruano andino. Se analizan además las diferencias obtenidas en los niveles de conservadurismo por sexo. Finalmente, se discute lo hallado a la luz de la evidencia sistemática hallada en otras investigaciones en contextos nacionales.
A REPRESENTAÇÃO DO COMBATENTE NA FICÇÃO DE ANTÓNIO LOBO ANTUNES: FANTASMAS DE UM PORTUGAL ANTIÉPICO
Authors: Von Pfeil Rommel Leonardo
Published: December 2018

Resumo O presente artigo analisa a representação antiépica do combatente português em três romances do escritor português António Lobo Antunes, sendo eles: Memória de elefante (1979), Os cus de Judas (1979) e Conhecimento do inferno (1980). A literatura portuguesa que tematiza a Guerra Colonial destaca-se por apresentar um discurso contrário ao modelo camoniano e ao seu discurso laudatório, buscando reinterpretar o sentido da história contemporânea de Portugal.  Para discutir o tema, usaram-se os teóricos Bakhtin (1998) e Anna Kalewska (2000).  Demonstrou-se, assim, que a ficção de Lobo Antunes constitui-se em um discurso antiépico, que causa uma ruptura na identidade e no imaginário coletivo nacional ao questionar, através da figura do combatente da Guerra Colonial, o discurso épico de fundação de toda a mitologia imperial lusitana, o que configura uma das suas marcas na história literária portuguesa. Palavras-chave: Antiépico; anti-herói; Guerra Colonial; identidade nacional; António Lobo Antunes
ETHOS E DISCURSO POLÍTICO: UMA ANÁLISE DO JOGO ENUNCIATIVO NA CARTA DE PRÉ-CANDIDATURA À VICE-PRESIDÊNCIA/2018, DA LÍDER INDÍGENA SÔNIA BONE GUAJAJARA
Authors: Silva Flávia Campos
Published: December 2018

O presente artigo é uma análise da construção do ethos no discurso político, a partir da articulação do jogo enunciativo na carta aberta de pré-candidatura da líder indígena Sônia Bone Guajajara, na disputa pelo cargo de vice-presidente nas eleições de 2018 pelo Partido Socialismo e Liberdade, PSOL. O embasamento teórico dará ênfase ao conceito de ethos na perspectiva de Dominique Maingueneau (2008) - sob o viés da Análise do Discurso - e a abordagem de aspectos do discurso político, enquanto processo de influência social, será norteada pelos pressupostos de Patrick Charaudeau (2008). Conclui-se que o discurso do sujeito enunciador (e mais especificamente a forma como ele é enunciado) aliado ao seu contexto de fala e condições de produção, constroi uma identidade que o posiciona estrategicamente ante sua pretensão política, contudo perde poder de alcance por estar posicionado numa lógica contrária à dinâmica de funcionamento da política nacional.
O CRIOULO DA GUINÉ-BISSAU É UMA LÍNGUA DE BASE PORTUGUESA? EMBATE SOBRE OS CONCEITOS
Authors: Timbane Alexandre António , Manuel Catia
Published: December 2018

A questão terminológica do termo pidgin surgiu pela primeira vez em 1850 (TARALLO, ALKMIM, 1987) para se referir a uma língua que surgiu da mistura entre o chinês e o inglês. Do pidgin surgiu o crioulo, uma língua natural que se formou em situações de contato linguístico (HLIBOWICKA-WĘGLAR, 2007). Os crioulos se formaram em espaços estrategicamente dominados por exploradores europeus. Na Guiné-Bissau se formou crioulo que é uma língua não oficial embora fosse uma língua franca ou veicular para a maioria dos guineenses (COUTO, 2002). Neste trabalho tenta-se questionar se o crioulo da Guiné-Bissau possui uma base portuguesa. Nesta pesquisa discute-se os conceitos de “base de uma língua” e os conceitos de “crioulo” e “pidgin”. Utilizando o método comparativo a pesquisa reflete a questão “base portuguesa” comparando com línguas africanas. Utilizando também o método bibliográfico se conclui que o crioulo da Guiné-Bissau precisa ter nome. Os dados mostram que o crioulo da Guiné-Bissau possui uma base de línguas bantu tendo emprestado algum léxico do português. Na pesquisa concluiu-se que o léxico é o mais evidente em todas as línguas, mas a base gramatical procura se conservar. O crioulo é uma língua africana que precisa de ser classificada tal como as outras línguas, havendo necessidade da produção de livros, dicionários e gramáticas que descrevem e demonstram as especificidades da língua. Seria necessário que ela seja oficializada para que seja língua de ensino não apenas nas escolas e universidades guineenses, mas também na vida da burocracia.
GÊNERO CHARGE: HUMOR E A CONSTRUÇÃO DA SUBJETIVIDADE NO FACEBOOK.
Authors: Sousa Oliveira José Luan , Facundes Leonildes Pessoa
Published: December 2018

RESUMO: Percebendo o avanço contínuo das tecnologias e o acesso cada vez mais amplo da sociedade ao mundo virtual, e principalmente às redes sociais, objetivamos nesse trabalho analisar a construção da subjetividade em funcionamento nas sociedades a partir dos conteúdos e significados que vão sendo produzidos no jogo da linguagem na mídia, bem como os sentidos dados a eles. Para isso, apropriamo-nos do gênero discursivo charge e as marcas das subjetividades dos sujeitos enunciadores divulgadas no Facebook por meio dos comentários. Para fins metodológicos, coletamos as charges e os comentários/enunciados publicados na página Humor Inteligente. Embasamo-nos teoricamente em Bakhtin (1997) para os gêneros do discurso, Araújo & Leffa (2016) para pesquisa das redes sociais; Rojo & Barbosa (2015) para Hipermodernidade e Gêneros discursivos, Possenti (2014) para a linguagem humorística, Amaral et al (2013), Orlandi (2007), Brandão (2012) para Análise do Discurso e Benveniste (2005) para subjetividade, entre outros. Os resultados revelam-nos que os componentes do gênero discursivo charge como a ironia, inteligência, sagacidade e humor, contribuem para a construção da subjetividade dos usuários que ao produzirem os efeitos de sentido comentam/enunciam marcando linguisticamente (ou não) a sua subjetividade. Isso comprova o pensamento de Benveniste (1958) sobre a linguagem ser a possibilidade da subjetividade.PALAVRAS-CHAVES: Charges. Discurso. Subjetividade.
Comunicación de la ciencia. Mucho más que explicar la física cuántica a las ancianitas
Authors: Francescutti Pablo
Published: December 2018

Presentación del Volumen 13 / N° 2 de la revista académica InMediaciones de la Comunicación dedicado al tema: Comunicación Social de la Ciencia. Nuevos actores, medios y miradas sobre la circulación del conocimiento científico.
Comunicación de la ciencia. Un aprendizaje desde y con las ciencias sociales y humanas
Authors: Hermelin Daniel
Published: December 2018

A partir de trabajos clásicos y contemporáneos de las ciencias sociales y humanas, este artículo rescata aportes susceptibles de contribuir al mejor entendimiento o al avance del subcampo de la Comunicación Pública de la Ciencia y la Tecnología (CPCyT), con énfasis en el ámbito latinoamericano y colombiano. Con este propósito se realiza un recorrido conceptual y crítico por los estudios de la comunicación, en cruces con el bagaje acumulado por las Ciencias Sociales y Humanas (CSyH), con paradas puntuales en la noción de reflexividad, en los paradigmas interpretativos y en las tensiones del binomio estructura-acción. Se concluye que el beneficio puede ser mutuo, como demuestran los estimulantes retos que arrojan a la reflexión actual en CSyH, los estudios de la comunicación en general y de la CPCyT en particular, específicamente en relación con los modelos de circulación del conocimiento.
La publicación de noticias sobre los resultados de I+D+i. ¿Cómo es percibida por los investigadores españoles?
Authors: Alonso-Flores Javier , Serrano-López Antonio Eleazar , Moreno-Castro Carolina
Published: December 2018

El objetivo de este estudio es conocer cuál es la percepción que tienen los investigadores de las universidades españolas sobre el impacto que generan, sobre sus carreras profesionales, las noticias científicas que se publican con los resultados de sus actividades de Investigación, Desarrollo e Innovación (I+D+i). Para ello, se han seleccionado los datos obtenidos por una encuesta online realizada en el año 2016 de 602 investigadores y profesionales de la comunicación científica de 20 universidades de España, teniendo único requisito que alguna de sus publicaciones hubiera sido objeto de —al menos— una nota de prensa difundida por su universidad en los últimos cinco años. Para el análisis de los datos se han utilizado el test de diferencia significativa entre variables (prueba de la Z) y el test de independencia de Kruskal-Wallis. Según los resultados obtenidos, el personal investigador confía en los comunicadores de su institución más que en los periodistas de otros medios, y percibe que divulgar su producción científica le otorga más beneficios que perjuicios, lo cual no deja de plantear desafíos en el terreno de la profesionalización y divulgación científica.
Formación en comunicación en los estudios de grado. Análisis en las áreas de ciencias de la salud y la vida, ciencias ambientales y ciencias naturales
Authors: Revuelta Gema
Published: December 2018

El objetivo de este trabajo es analizar la formación en comunicación que reciben los alumnos que cursan estudios de grado en las áreas de ciencias de la salud y de la vida, las ciencias ambientales y las ciencias naturales. Para ello se ha estudiado el conjunto del sistema universitario español (84 universidades) y una muestra de 10 universidades pertenecientes a seis países latinoamericanos. A partir de un análisis documental de sus sitios web, se han identificado 91 asignaturas que reúnen los criterios de inclusión: 48 en el grado de medicina, 18 en ciencias de la vida (biomedicina y biotecnología, fundamentalmente), 13 en ciencias ambientales y otras ciencias naturales y 12 en otras ciencias de la salud (psicología, enfermería, nutrición, farmacia, gerontología, neurociencias y veterinaria). Asimismo, el análisis de contenido de los programas docentes de estas asignaturas ha permitido identificar siete categorías temáticas: 1) teorías de la comunicación y de las intervenciones basadas en la comunicación; 2) la comunicación en acción: actores, relaciones interpersonales y entornos; 3) naturaleza de la ciencia y elementos específicos del campo disciplinar; 4) comunicación en medios y su impacto social; 5) aspectos éticos; 6) habilidades y técnicas de comunicación generales y 7) habilidades en situaciones especiales.
Todo termina aquí y Febrero 30
Authors: Álvez Francese Francisco
Published: December 2018

Las vidas y las obras de Gustavo Espinosa (Treinta y Tres, 1961) y Amir Hamed (Montevideo, 1962-2017) están entrecruzadas de tal manera que sería un trabajo en sí mismo compilar las numerosísimas menciones cruzadas en entrevistas, ensayos o ficción, citas, prólogos, comentarios críticos, presentaciones y contratapas de libros. Con sus últimas novelas publicadas a la fecha, Todo termina aquí y Febrero 30 respectivamente, esa relación se vuelve, si cabe, más estrecha, porque además de la aparición (velada en un caso, manifiesta en otro) de los nombres y las figuras de cada uno en ambas obras, éstas, aunque muy disímiles, comparten un tema central: el fin del mundo.
Development of a Short-Form of the Medication Management Test: Evaluation of Dimensionality, Reliability, Information and Measurement Equivalence Using Latent Variable Models
Authors: Teresi Jeanne A. , Ocepek-Welikson Katja , Ramirez Mildred , Fieo Robert , Fulmer Terry , Gurland Barry J.
Published: December 2018

Background and Purpose: The Medication Management Test (MMT) measures higher cognitive functioning. The aim of the analyses presented was to reduce assessment burden by developing a short-form version, and describe its psychometric properties. Methods: Factor analyses, item response theory (IRT), and differential item functioning (DIF) were performed to examine the dimensionality, reliability information, and measurement equivalence. Results: The ratio of the first two extracted eigenvalues from the exploratory principal component analysis was 7.62, indicating essential unidimensionality. Although one item “needs prompting for pill regime” evidenced DIF above the threshold for education and race/ethnicity, the magnitude was relatively small and the impact minimal. IRT-based reliability estimates were high (>0.80) across all subgroups. Conclusions: Because medication management is an important task associated with independent living, it is critical to assess whether medications can be self-administered safely.
Development and Psychometric Evaluation of an Instrument to Measure the Use of Intuition in Clinical Practice by Critical Care Nurses
Authors: Hassani Parkhide , Abdi Alireza , Jalali Rostam , Salari Nader
Published: December 2018

Background: The current study was conducted to develop and validate an instrument to measure the use of intuition in clinical practice by critical care nurses. Methods: Item generation and psychometric evaluation were developed. In the psychometric, content validity index and content validity ratio were calculated to establish initial instrument validity through the use of expert ratings, as well as, construct and criterion validity. Results: The original items reduced to 25. Using principal components analysis and orthogonal varimax rotation, three factors had an eigenvalue >1, with 60.05% variance (Factor 1: 47.9%; Factor 2: 7.56%; and Factor 3: 5.05%). The tool had an acceptable correlation to criterion of the instrument (r = .769, p < .001), a Cronbach alpha consistency of 0.953, and a stability level of r = .945 and p < .001. Conclusion: In this study, a valid and reliable instrument was developed to measure intuition.
Avrupa Birliği, Almanya ve Türkiye: İlişkilerde Temel Değerler ve Dönüşen Stratejiler
Authors: ERDOĞAN Seven
Published: December 2018

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Model Strategi Tumbuh Dan Bertahan Pada Pengelolaan Baitul Maal Wat Tamwil (BMT) Di Kabupaten Tulungagung Dan Ponorogo
Authors: Susilowati Lantip
Published: December 2018

BMT faces internal business challenges from managers. External challenges come from members, business competitors and economic conditions. BMTs face obstacles in managing business growth strategies and survival strategies. The focus of the problem in this study; 1) What is the growth strategy for the management of Baitul Maal wat Tamwil? 2) How do you survive the management of Baitul Maal wat Tamwil? 3) Are there obstacles faced in the effort to grow and survive the management of Baitul Maal wat Tamwil (BMT)? This study was examined with a qualitative and interpretive type approach. The results of this study: 1) The growth strategy of BMT management is done by maximizing network and employee functions, the product contains the value of core product benefits and improved benefits, spatial planning shows fast service, contains art, and member comfort, promotion is carried out in the form of external marketing, internal and interactive. 2). Defending strategies in BMT management: not adding employees when not increasing productivity, removing mudharabah time deposits, profit sharing according to sharia, BMT Dinar Amanu still applies a special rate of 1% for mudharabah deposits, Supervision is carried out with supervision of all employees, DPS BMT Dinar amanu function not maximal. 3) Constraints faced in efforts to grow and survive on BMT management include lack of competent Human Resources, ready to challenge, less agile and less agile and KUR fund competition.
Mustansir Mir and a Contemporary Literary Approach to the Qaṣaṣ al-Qur’ān: Study of Qur’anic Story of Joseph
Authors: Matswah Akrimi
Published: December 2018

The textuality of the Qur'an contains a high quality of literary aspect. Therefore, a literary approach to the Qur’an is one of the ways in the understanding of the meaning and message of it. This approach has been used by modern and contemporary Muslim scholars, and even by western scholars of Qur’an studies. This paper discusses Mustansir Mir’s thought and literary approach to the Qur’an, focusing on the story of Joseph. This study shows that Mir reflects on the nature and power of God and reveals the moral messages in the scene and structured dialogue on the passages in Sūra Yūsuf. It also reveals that Mir’s approach to the story is structural where he elaborates the structure, plot, and scene of the story and connects them with the moral message of the story.
Undergraduate Nursing Students’ Caring Behaviors: A Cross-Sectional Study
Authors: Wolf Zane Robinson , Byrne Deborah , Hanson-Zalot Mary
Published: December 2018

This cross-sectional, comparative descriptive design study aimed to compare self-reports of perceived caring, measured by the Caring Behaviors Inventory-16 Student Version, in a convenience sample of undergraduate nursing students across three levels of the curriculum, second, third, and fourth years. The study evaluated their confidence in providing nursing care with a professional confidence Visual Analog Scale. Combined perceived caring and confidence scores increased on posttest and differed at a statistically significant level between pretest and posttest. Pretest and posttest perceived caring scores differed significantly among the three curriculum levels, for pretest confidence, but not for posttest senior level confidence. Convergent validity testing revealed a weak association between perceived caring and confidence in providing nursing care for patients. Cronbach’s alpha for the CBI-16 Student Version established beginning reliability. Perceived caring may be unintentionally part of a hidden curriculum through student experiences with patients, registered nurses, and faculty who model caring behaviors.
Validity and Reliability of the Instrument for Assessing the Child’s Constitution (ICC): Individualising Processes in Diagnosing Children With a Developmental Disorder
Authors: Niemeijer M. H. , Baars E. W. , Hoekman J. , Ruijssenaars A.J. J.M.
Published: December 2018

In children developmental disorders expresses themselves by a variable presentation of symptoms and frequent manifestation of comorbidity of a complex nature. In addition to the classification of a disorder, individualising diagnostics is a means to realize assessment and treatment that are fine-tuned to the child.In the day to day care of children with a developmental disorder the Instrument for assessing the Child’s Constitution (ICC) is a supporting means to map out the child’s individual situation. The instrument is based on an anthroposophic anthropology and typology. It provides an individualised diagnosis by mapping the degree of (dis)balance in child development. In three developmental fields, the cognitive, the affective and the conative field, the (dis)balance of functioning is assessed by the ICC. The instrument consists of two parts. With reference to the three fields part I consists of 36 items, each having a subscale with 12 polar formulated items on a seven-point scale. For each of the three fields part II includes a visual analogue scale (VAS). The results of Part I and II are made comparable by putting them both on a ten-point scale. The results are graphically represented as a profile of the constitution.In this article we present the results of a study with the ICC on psychometric properties in a research group (n=535) and a control group (n=148). As reference of the assessment of the quality of the ICC a Consensus-based Standard for the selection of health Measurement Instruments is used.
SAĞLIĞIN DİJİTALLEŞMESİ - DIGITALIZATION OF HEALTH
Authors: DEMİRCİ Şenol
Published: December 2018

Teknolojideki gelişmeler bireylerin teknolojik araçlara ve uygulamalara olan erişimini arttırma ve bireylerin dijital ortamda faaliyetlerini yerine getirmesine neden olmuştur. Dijital teknolojiler insanları birçok şekilde etkisi altına almış durumdadır. Sağlık ve sağlık hizmetlerini de etkisi altına alan bu teknolojilerin, iş verimliliğini arttırmak, hizmet kalitesini yükseltmek ve güvenli bir hizmet çevresi oluşturmak gibi etkileri bulunmaktadır. Bu teknolojiler veri yönetimi ve analizi, mobil teknolojiler, sosyal ağlar, internet, e-mail, giyilebilir veya vücuda yerleştirilebilir yüksek düzeyli uygulamaları ve araçları kullanarak insan sağlığının geliştirilmesini amaçlamaktadır. Bu teknoloji ve uygulamalar bireyin sağlık durumu hakkında doktora ya da ilgili diğer sağlık çalışanına gerçek zamanlı veriler sağlayarak bireyin sağlık durumunun sürekli kontrol altında tutulmasına imkan sağlamaktadır. Çevresel, davranışsal, psikolojik ve fiziki açıdan bireyin sağlık durumunu izlemeye imkan veren bu teknolojiler daha kontrol edilebilir, verimli ve etkili bir sağlık sisteminin oluşumuna öncülük etmektedir. Çalışmada, günümüz sağlık hizmetlerinde ve sağlık hizmetleri kullanıcıları tarafından kullanılmaya başlanan ve gelecek yıllarda kullanımının yaygınlaşması beklenen dijital sağlık teknolojileri ve uygulamalarından, faydalarından, sakıncalarından ve ülkemizdeki mevcut durumdan bahsedilecektir.
EHLİ SALİB’E KARŞI TÜRKİYENİN MUTABAKAT METNİNİ YAZAN AKİF’İ, KÜRESEL TAARRUZLARIN ARTTIĞI GÜNÜMÜZDE, YENİDEN OKUMAK/ANLAMAK
Authors: Aytekin Arif
Published: December 2018

Toplum ve millet ile ilgili her gelecek tasarımı geçmişi hesaba katmayı gerektirir. Hatta bu bakımdan toplum ve millet meseleleri ile ilgili tarih yazımları paradoksal bir biçimde geleceği dikkate alarak geçmişin yeniden yorumlanması ve geleceğe ışık tutması açısından önemsenir. Bu minvalde Yahya Kemal’in veciz ifadesi “geçmişteki ati” motto deyişi dikkate değerdir. Bu çalışmada sondan geriye doğru başta İsmet Özel’in “İstiklal Marşı Derneği” çatısı altında sarf ettiği düşüncelerinden kalkarak, Nurettin Topçu üzerinden Mehmet Akif Ersoy’a doğru kesintisiz milli bir düşünce çizgisinin izi sürülmektedir. M. Akif’te “tek dişi kalmış canavar” metaforu ile biçimlenen modern dünya eleştirisi, Nurettin Topçu ve İsmet Özel’de “dünya sistemi” çerçevesinde, ulus-devletlere yönelen küresel baskılar bağlamında daha sistematik anti emperyalitst bir düşünceye evirilmiştir. İstiklal Harbi’nin kazanılmasında çok önemli bir motivasyon kaynağı olan ve “kahraman orduya” atfedilen “İstiklal Marşı”mızın aynı zamanda günümüzde toplum ve millet olarak karşı karşıya olduğumuz küresel taarruzları geri çevirebilecek fikri tohumları içinde barındırdığı düşünülmektedir. Bu çerçevede Akif’in Fikirlerinin billurlaştığı İstiklal Marşı, Türkiye toplumunun toplumsal bütünleşmesinde bir “istinat yeri” ya da “mutabakat metni” olarak en üst ve geniş çerçevede toplumsal uzlaşma çatısı olarak yeniden değerlendirmeye sunulmaktadır.
ÜNİVERSİTE ÖĞRENCİLERİNİN SİGARA BAĞIMLILIĞINDA SOSYAL ÖĞRENMENİN ROLÜ ÜZERİNE NİTEL BİR İNCELEME - A QUALITATIVE STUDY ON THE ROLE OF SOCIAL LEARNING IN CIGARETTE ADDICTION TO UNIVERSITY STUDENTS
Authors: Sağar Mehmet Enes
Published: December 2018

Bağımlılık yapan maddelerin en yaygınlarından biri de sigaradır. Sigara her geçen gün hem dünyada hem de ülkemizde hızlı bir biçimde yaygınlık kazanmaktadır. Bu bağlamda her yaş kesimi için önemli bir problem haline dönüşmüştür. Yaşam dönemleri bakımından her dönem için önemli bir sorun olmasına karşın gençlik dönemi sigaraya başlama ve bağımlılık bakımından daha riskli bir dönem olarak görülmektedir. Sigara bağımlılığında en riskli dönemlerden olan gençlik döneminde gençler sigara kullanımı davranışını çeşitli sebeplerle öğrenmektedirler. Bu öğrenme şekillerinden bir tanesi de sosyal öğrenme teorisi bağlamında model alma davranışı yolu ile öğrenmedir. Bu çalışma, üniversite öğrencilerinin sigara kullanma davranışında sosyal öğrenmenin rolünün etkisini araştırmak için yapılmıştır. Araştırma 15 üniversite öğrencisi ile gerçekleştirilmiş bir nitel araştırmadır. Veri toplama aracı olarak görüşme tekniğinden yararlanılmıştır. Sonuçlar içerik analizi ile değerlendirilmiştir. Araştırmadan elde edilen bulgular şunlardır: Sigara ile tanışma yaşının genellikle lise yıllarında olduğu ancak ilköğretim yaşına kadar da düştüğü görülmüştür. Üniversite öğrencilerinin sigaraya başlama nedenleri arasında en fazla arkadaşların etkili olduğu, sigara kullanımının en çok arkadaş ortamında arttığı ve öğrencilerin sigara kullanımını model alma bağlamında en çok arkadaşlarından etkilendikleri bulunmuştur.
İSLAM’IN TURİZM’E YANSIMASI: HELAL TURİZM - REFLECTION OF ISLAM TO TOURISM: HALAL TOURISM
Authors: YILDIZ Savaş , YILDIZ Zafer
Published: December 2018

Müslümanların artan nüfusunun yanı sıra Müslüman ülkelerin refah seviyesindeki olumlu gelişmelere bağlı olarak turizm amaçlı seyahat eden dini hassasiyete sahip Müslüman turist sayısı da artış göstermiştir. Yaşanan bu gelişmeler “helal” anlayışındaki öneminin artmasına yol açmıştır. “Helal” anlayışı ile ilgili artan farkındalık neticesinde birçok Müslüman ve Müslüman olmayan ülkeler Müslüman turistleri ülkelerine çekerek helal turizm pazarından paylarını arttırma çabası içine girmişlerdir. Geniş kapsamlı literatür taramasına dayanan bu çalışmada İslam dininde seyahatin yeri ile ilgili çeşitli Kur’an ayetlerinin ve hadislerin yanı sıra helal turizm yaklaşımı ile ilgili temel kavramlar ele alınmış ve dünyada helal turizmin ekonomik boyutu ve Türkiye’nin konumu incelenmiştir.
CLINOPODIUM ALBANICUM (GRISEB. ex K. MALÝ) MELNIKOV NEW SPECIES FOR THE FLORA OF THE REPUBLIC OF MACEDONIA
Authors: Matevski Vlado
Published: December 2018

During floristical investigation in western parts of the Republic of Macedonia one new species of vascular plants was found which was not previously reported for the country – Clinopodium albanicum (Griseb. ex K. Malý) Melnikov.
The Technique for Organ Retrieval with Inner Transverse Transection of Abdominal Wall Floors Except for Skin
Authors: Çakır Tuğrul , Aslaner Arif , Eyvaz Kemal , Kazan Murat Kazım
Published: December 2018

Aim: To describe a technique for retrieval of abdominal organs of a cadaveric donor Methods: Only the inner transverse transection of abdominal wall floors except skin was performedResults: The good exposure of abdominal closure with the retrieval of the liver, both kidneys and spleen easily.Conclusion: The technique can be feasible in cadaveric organ retrieval from the abdomen.
An Instrument to Measure Mental Health Professionals’ Beliefs and Attitudes Towards Service Users’ Rights
Authors: Eiroa-Orosa ​Francisco José , Limiñana-Bravo Laura
Published: December 2018

We aimed at developing and validating a scale on the beliefs and attitudes of mental health professionals towards services users’ rights in order to provide a valid evaluation instrument for training activities with heterogeneous professional groups. Items were extracted from a review of previous instruments, as well as from several focus groups which have been conducted with different mental health stakeholders. The preliminary scale consisted of 44 items and was administered to 480 mental health professionals. After eliminating non-discriminant and low weighting items, a final scale of 25 items was obtained. Exploratory and confirmatory factor analyses produced a four-factor solution consisting of four dimensions; system criticism/justifying beliefs, freedom/coercion, empowerment/paternalism and tolerance/discrimination. The scale shows high concordance with our theoretical model as well as adequate parameters of explained variance, model fit and internal reliability.
Modelling Built-Settlements between Remotely-Sensed Observations
Authors: Nieves Jeremiah J. , Sorichetta Alessandro , Linard Catherine , Bondarenko Maksym , Steele Jessica , Stevens Forrest , Gaughan Andrea E. , Carioli Alessandra , Clarke Donna , Esch Thomas , Tatem Andrew J.
Published: December 2018

Mapping settlement extents at the annual time step has a wide variety of applications in demography, public health, sustainable development, and many other fields. Recently, while more multitemporal urban feature or human settlement datasets have become available, issues still exist in remotely-sensed imagery due to coverage, adverse atmospheric conditions, and expenses involved in producing such feature sets. These challenges make it difficult to increase temporal coverage while maintaining high fidelity in the spatial resolution. Here we demonstrate an interpolative and flexible modeling framework for producing annual built-settlement extents. We use a combined technique of random forest and spatio-temporal dasymetric modeling with open source subnational data to produce annual 100m x 100m resolution binary settlement maps in four test countries of varying environmental and developmental contexts for test periods of five-year gaps. We find that in the majority of years, across all study areas, the model correctly identified between 85-99% of pixels that transition to built-settlement. Additionally, with few exceptions, the model substantially out performed a model that gave every pixel equal chance of transitioning to the category “built” in each year. This modelling framework shows strong promise for filling gaps in cross-sectional urban feature datasets derived from remotely-sensed imagery, provide a base upon which to create future built/settlement extent projections, and further explore the relationships between built area and population dynamics.