bluuebunny/crossref_metadata_2025 huggingface dataset:
The new working-class youth employment of catering organizations during the pandemic
Authors:   Samara National Research University, Bocharov Vladislav Yu. ,   Russian Federation Sociological Institute of the RAS — a branch of the Federal Research Sociological Center of the Russian Academy of Sciences,   Russian Federation Industrial University of Tyumen
Published: June 2022

The article discusses the specific characteristics of the employment of young workers of Russian catering organizations during the COVID-19 pandemic. Among such characteristics, the following points stand out: the predominantly informal nature of labor relations; the routine nature of work under the control of the employer, carried out with the help of video surveillance; the dependence of the working day on the presence or absence of visitors (“guests”) in the organization; and the flexibility of the work schedule. Working youth of customer service is one of the groups of employees most affected by the pandemic. Based on the results of indepth interviews with young workers at three public catering organizations in Samara, conclusions are drawn about negative consequences of the pandemic. These are expressed by the young workers in the following: an increase in the risk of dismissal or unpaid vacation; working in the conditions of reduced working hours; reduction of wages; constant conflicts with visitors of catering organizations due to the mask regime; and prohibition of corporate events. In addition to the in-depth interview data, statistical data and other empirical data obtained within the framework of the ongoing research project “Life strategies of new working-class youth in modern Russia”, carried out with the participation of the author (2018–2021), are presented. In the theoretical aspect, the conclusion is made about the prospects of using the interdisciplinary approach “new working class studies”, which synthesizes the neo-Marxist (conflict) and cultural approaches, as well as the concept of “behavioral economics” to the analysis of employment problems in the service sector. Moreover, with such a methodology the precarious nature of the employment of service workers and the fact that the pandemic has a negative impact on all areas of their lives should be taken into account
Transnational online education and digital inequality: Issues of pedagogical design
Authors:   St. Petersburg State University, Pashkov Mikhail V. , Pashkova Valeria M. ,   Victoria University, Starostenko Vladimir A. ,   St. Petersburg State University
Published: June 2022

Digitalization of education is commonly seen as a process that contributes to societal progress rather than as a factor that gives rise to the digital divide in society. This paper therefore considers how the digital divide can impact students and their learning in transnational online education which has been in greater demand since the onset of the pandemic. Methodologically, the paper draws on the digital inequality stack model showing how each level of the stack — physical access to information and communication technologies; digital skills and competency; purposes and motivations for technology use — can influence learning experiences in distance online education. This paper contributes to the literature on digital inequalities in higher education in the following three ways: by further articulating the levels and aspects of digital inequalities in the context of online learning; by demonstrating how pedagogical design can contribute to redressing some of the challenges experienced by students as a result of digital inequalities; and by offering a practical model of pedagogical design in the form of a checklist that helps identify and mitigate the effects of digital inequalities on online learning. The paper also makes some critical remarks about the concept of the digital divide that are relevant to the development and implementation of online programs and courses. This paper may be of interest to education providers planning to participate in transnational online education.
The schism in postnonclassical rationality
Authors:   Perm State University, Loskutov Yuri V.
Published: June 2022

Ontological, epistemological, socio-practical, and ethical aspects demonstrate the impossibility of the coexistence of the complex idea of human dimensionality with the complex idea of nonlinearity in the “hard core” of postnonclassical research programs. The idea of human dimensionality, which necessarily has a real paradigmatic status in postnonclassical science, seriously limits the worldview ideas of nonlinearity in favor of linear concepts. The claim of the worldview of nonlinearity to paradigmatic status in postnonclassics leads to the loss of compatibility of this idea with the idea of human dimensionality, which demonstrates the groundlessness of this claim. In the ontological aspect, the human being is seen as a result and a condition for the continuation of a linear world process. The epistemological aspect notes the insufficiency of any reductionist cognitive strategy to ensure the unity of human knowledge, and states the immaturity of the current state of social synergetics. In the socio-practical aspect, the project as the main type of linear activity, which occupies a central place in human culture, is opposed to the game as the main type of non-linear activity. At the same time, the anti-project nature of reliance on nonlinear processes is noted. In the ethical aspect, the incompatibility of postnonclassical rationality with ethical relativism, naturally arising from the claim of the idea of nonlinearity to paradigmatic status, is considered. Present in the “hard core” of the postnonclassical research programs the complex idea of human dimensionality can be protected by different elements of the “protective belt”: on the one hand, either by the emphasis on the study of linear processes or by the emphasis on the study of nonlinear processes (using a “soft,” non-paradigmatic variant of the idea of nonlinearity); on the other hand, either by means of synergetics, or by means of concrete-universal dialectics.
Wrapping of the ascending aorta: history and prospects
Authors: Akulov V.A. , Alsov S.A. , Sirota D.A. , Lyashenko M.M. , Chernyavskiy A.M.
Published: June 2022

Historically, exoprosthetics is one of the first surgical procedures used for aneurysmal dilatation of such great vessels as the aorta. Despite the acceptable results of this method it is not widespread now because of the possible negative consequences of aortic wall wrapping (rupture or dissection).
According to the latest guidelines, it is necessary to consider prosthetics of the ascending aorta by the patients with aortic valve surgery and aneurysmal dilatation of the ascending aorta more than 45 mm. However, early postoperative mortality reaches 20 % by elderly patients with severe comorbidities. In such situations, it is worth to choose a less traumatic surgical approach. Exoprosthetics of the aorta reduces the invasiveness of procedure, time of artificial circulation and aortic occlusion thereby taking down the risks of early postoperative complications.
The purpose of this literature review is to analyze the current data on the technique of exoprosthetics of the aorta by the patients with moderate ascending aorta dilatation. The Scopus, Web of Science, PubMed databases were used for searching and selecting literature sources.
The results demonstrate that aortic wrapping is a safe method causing rapid and permanent aortic remodeling. The technique has comparable long-term results with prosthetics of the ascending aorta despite the presence of histological changes in the aortic wall with a changing in its mechanical properties.
Received 28 September 2021. Revised 19 January 2022. Accepted 20 January 2022.
Funding: This work was carried out within the framework of the state task of Ministry of Health of Russian Federation No. 121032300337-5.
Conflict of interest: Authors declare no conflict of interest.
Contribution of the authorsConception and study design: S.A. Alsov, D.A. SirotaDrafting the article: V.A. AkulovCritical revision of the article: S.A. Alsov, D.A. Sirota, M.M. Lyashenko, A.M. ChernyavskiyFinal approval of the version to be published: V.A. Akulov, S.A. Alsov, D.A. Sirota, M.M. Lyashenko, A.M. Chernyavskiy
New tool for Gram-negative and Gram-positive bacterial strains differentiation through GCMS direct identification of exogenous VOC metabolites in headspace vials
Authors:   National Research and Development Institute for Industrial Ecology, Chiriac Florentina Laura , Petre Andreea Valentina ,   National Research and Development Institute for Industrial Ecology, Stoica Catalina ,   National Research and Development Institute for Industrial Ecology, Paun Iuliana ,   National Research and Development Institute for Industrial Ecology, Pirvu Florinela ,   National Research and Development Institute for Industrial Ecology, Cristea Ionut ,   National Research and Development Institute for Industrial Ecology, Vasilache Nicoleta ,   National Research and Development Institute for Industrial Ecology, Niculescu Marcela ,   National Research and Development Institute for Industrial Ecology, Serban Gabriel ,   National Research and Development Institute for Industrial Ecology, Iancu Vasile Ion ,   National Research and Development Institute for Industrial Ecology
Published: June 2022

In this paper, a chromatographic method for the determination of volatile organic compounds (VOCs) as a tool for Gram-positive and Gram-negative bacterial strains identification was described. Direct Headspace gas chromatography coupled with mass spectrometry (Headspace-GC-MS) has been used for the qualitative determination of VOCs emitted by certain bacterial strains (Salmonella Typhimurium, Escherichia coli, Serratia rubidae, Staphyloccocus aureus, Enterococcus casseliflavus, and Enterococcus faecalis). In the first stage of the study, pathogenic bacteria were cultured in broth-specific liquid culture medium directly (lauryl sulfate broth) into headspace vials. Subsequently, the VOC emissions were analyzed by airborne screening in the headspace vials. Thus, the objective was to analyze all the resulting volatile organic compounds in order to select only those compounds, which can be exclusively associated with specific pathogenic bacteria. Qualitative analysis by Headspace-GC-MS has proven to be a non-invasive, accurate, and fast method for identifying certain bacterial strains, based on VOCs emission. A considerable number of volatile organic compounds have been determined in the headspace air, a significant difference being observed between the VOCs emitted by bacterial cultures compared to the culture medium but also between the types of bacterial cultures themselves. The study presents preliminary results, which prove that the identification of the studied pathogenic bacteria is possible, based on the determination of certain types of VOCs in the headspace air of these cultures. This method can be used successfully for the rapid identification of bacterial culture types compared to classical methods.
Mitigation of QingLuoTongMai Pills on Chemotherapy-induced Phlebitis: A Network Pharmacology Study and Experimental Validation
Authors: Yu Ning , Zhang Shi-Kai , Chen Jian , Zhao Cheng , Cao Ye-Min , Li Ling , Cao Yong-Bing
Published: June 2022

Objective:

Chemotherapy-induced phlebitis (CIP) is a side product of chemotherapy
treatment for malignant tumors, which affects the therapeutic effect and quality of life of cancer
patients, and still lacks a clear therapeutic means. In this study, we investigated the therapeutic effects
of QLTMP on CIP using network pharmacology and verified the anti-inflammatory mechanism
of QLTMP in a mice model induced by vinorelbine.

Methods:

Network pharmacology analysis was performed to identify bioactive compounds in
QLTMP. The protein-protein interaction network was used to identify the core therapeutic targets of
QLTMP against CIP, analyze biological function and pathway enrichment based on the identified
core therapeutic targets, and evaluate the therapeutic effect of QLTMP in a model of CIP induced
by vinorelbine to confirm the reliability of the network pharmacological analysis.
One hundred and sixty-five bioactive compounds of QLTMP matched the screening criteria and
identified 19 core therapeutic targets of QLTMP against CIP. Biofunctional analysis showed that
the therapeutic effect of QLTMP on CIP was mainly related to the inhibition of inflammation, while
pathway enrichment analysis showed that the TNF signaling pathway was involved in the inflammatory
process.

Results:

Experimental confirmation in a mice model showed that QLTMP exerts anti-inflammatory
effects through modulation of the PI3K/AKT/TNF signaling pathway, a discovery consistent with
the network pharmacological analysis.

Discussion and Conclusion:

The network pharmacological analysis of the anti-inflammatory
mechanism of QLTMP on CIP and its exploration of in vivo experiments provide a theoretical basis
for the design of agents that can mitigate or cure CIP.
TIGIT as a Novel Prognostic Marker for Immune Infiltration in Invasive
Breast Cancer
Authors: Guo Chenming , Luo Zhiwen , Ismtula Dilimulati , Bi Xiaojuan , Kong Han , Wang Yiyang , Yang Zhen , Mao Xinmin
Published: June 2022

Background:

To assess the levels and potential therapeutic and prognostic significance
of TIGIT in invasive breast cancer.

Methods:

The Cancer Genome Atlas database was used to evaluate TIGIT levels in invasive breast
cancer and its association with clinicopathological features. Immunohistochemistry (IHC) was performed
to validate it. Further, the Kaplan-Meier survival curve, univariate and multivariate Cox regression
models were applied in analyzing the role of TIGIT in the prognosis of invasive breast
cancer. Go / KEGG enrichment analyses techniques were used to investigate the possible cellular
mechanism, and string database was used to explore TIGIT-related proteins. Finally, the TIMER
database was used to determine the association between TIGIT and immune cell infiltrations.

Results:

TIGIT was differentially expressed in Pan cancer tissues compared with normal tissues.
Relative to normal tissues, TIGIT levels in invasive breast cancer were elevated (p<0.05). TIGIT
mRNA level was significantly different from T stage, age, ER and PR level (p<0.05). The high
levels of TIGIT exhibited positive correlations with PFI and OS (p<0.05). Univariate analysis revealed
that age, clinical stage, high TNM stage, menopausal status and radiotherapy were the factors
affecting OS (p< 0.05). Multivariate analysis revealed that age, high clinical stage and menopausal
status were independent risk factors for tumor progression (p<0.05). CD226, INPP5D,
PVR, PVRL2 and PVRL3 proteins interact with TIGIT. The TIGIT levels were significantly correlated
with infiltrations of immune cells (such as CD8+ T cells) (r=0.917, p<0.05).

Conclusion:

TIGIT is elevated in invasive breast tumor and is closely associated with the prognosis
of invasive breast cancer. TIGIT may be the target of immunotherapy for invasive breast cancer.
Development of a Novel Self-Dissolving Microneedle-Assisted Percutaneous
Delivery System of Diacerein through Solid Dispersion Gel: Solubility
Enhancement, Proof of Anti-inflammatory Activity and Safety
Authors: Shabbir Maryam , Barkat Kashif , Ashraf Muhammad Umer , Nagra Uzair
Published: June 2022

Background:

Diacerein, an osteoarthiritis drug, experiences slow topical permeation due to
limited solubility. Additionally, it shows a laxative effect due to acid/base hydrolysis of the drug in the
colon.

Objective:

Diacerein solubility was improved to increase percutaneous drug delivery.

Methods:

To improve saturation solubility of the drug, Diacerein was pre-treated with Polysorbate 80
aqueous solution (1% v/v) to obtain lyophilized powder after wet milling or formulated as solid dispersion
using PEG 4000 by fusion method. The lyophilized Diacerein in hydroxypropyl methylcellulose
(HPMC 8% w/w) and polyvinyl pyrrolidone (PVP 30% w/w) matrix, with PEG 400 as co-solvent, provided
an optimized array. The solid dispersion was loaded in the CMC based gel for subsequent administration
on dissolving microneedle-treated skin.

Results:

The addition of PEG 400 increased Diacerein loading in microneedles to 390.35±4.28 μg per
array. The lyophilized drug displayed amorphous characteristics in the dissolving microneedles as per
XRD analysis. SEM photographs showed uniformity in the surface topology of microneedles. The needles
showed rapid polymer dissolution within 5 minutes, whereas methylene-blue distribution confirmed
the formation of microcavities in excised rat skin. The drug-loaded arrays showed better permeation
(74.39%) and skin deposition (15.75%) after 24 hours, however, ⁓12% of Diacerein remained in the
baseplate. This led to the tailoring of CMC-based gel (3% w/v) containing 0.4% solid dispersion of
Diacerein. When compared to untreated skin, the gel improved permeation rate by 2.43 folds through
aqueous microchannels generated by dissolving microneedle pre-treatment and allowed 98% drug permeation.
The quasi-Fickian diffusion mechanism was found to drive ex vivo release kinetics, with a
shorter lag time (0.88 h) and higher flux (26.65 μg/sq.cm.h). Microneedle-assisted Diacerein gel showed
a positive anti-inflammatory effect in the paw edema model and reduced diarrheal episodes in comparison
to the marketed oral formulation. The gel showed desired characteristics at 5°C±2°C when tested
under accelerated stability conditions.

Conclusion:

The present study reports for the first time the verification of efficacy and safety to advocate
the suitability of Diacerein for percutaneous delivery through dissolving microneedle-treated skin.
Novel 2-alkylthio-1-benzylimidazole-5-carboxylic Acid Derivatives Targeting
Gp41: Design, Synthesis, and In Vitro Anti-HIV Activity Evaluation
Authors: Fassihi Afshin , Mostashari-Rad Tahereh , Claes Sandra , Schols Dominique , Shirvani Pouria
Published: June 2022

Background:

Although current available medications have increased the quality of life in HIV-infected patients, there are still some shortcomings in HIV treatment arising from viral resistance, drug side effects and high cost of medication. Therefore, there is an urgent need for some suitable HIV inhibitors with different mechanisms of action. Gp41, located on the HIV cell surface, plays an important role in the fusion of viral and host cell membranes. With the same structure in different HIV strains, gp41 seems to be a promising target for developing novel HIV fusion inhibitors.

Objective:

Based on the essential structural elements of gp41 inhibitors, two series of compounds were prepared and their inhibitory effect on HIV cell growth was investigated. Compared to the known small-molecule gp41 inhibitors, 2-Alkylthio-1-benzylimidazole-5-carboxylic acid (series I) and (E)-4-{[5-(((1-benzyl-1H-1,2,3-triazol-4-yl)methoxyimino)methyl)-2-(alkylthio)-1H-imidazol-1-yl]methyl}benzoic acid derivatives (series II) had more flexible skeleton with extra moieties interacting with the gp41 key residues.

Method:

In silico drug design approaches including molecular docking and molecular dynamics simulations were employed to design these novel compounds prior to preparation. The designed compounds exhibited proper chemical interactions and stable complexes with gp41. Then, the selected candidates were efficiently synthesized, and their anti-HIV-1 and anti-HIV-2 activities, as well as their cellular cytotoxicity in MT-4 cells were determined.

Results:

None of the compounds belonging to the series I were active against HIV-1 and HIV-2 replication in cell cultures, and most of the compounds in series II exhibited significant cytotoxicity against MT-4 cells in low micro molar concentrations.

Conclusion:

The smaller molecular structures of the compounds in series I might be responsible for their poor anti-HIV effects. The high toxicity of the series II compounds on the host cell makes it impossible to assess their anti-HIV activities.
A Review of Organic Dye Based Nanoparticles: Preparation, Properties,
and Engineering/Technical Applications
Authors: Mahato Kapil Dev , Kumar Uday
Published: June 2022

Organic dye-based nanoparticles (ODNPs) are fabricated with desired morphologies using
laser ablation, reprecipitation, ion association, and self-assembly methods. Primitively, this review introduces the theory of the molecular origins of dye aggregation, manifestations of the formations of
monomer to J-dimer, H-dimer, and oblique dimer (mixed J and H dimer) in ODNPs. Although, organic
dye nanoparticles have better basic properties than their monomer counterparts. These nanoparticles
are suitable candidates for many engineering and technical applications. Furthermore, we have discussed OLEDs, optoelectronics, sensing, environmental, light-harvesting antennas, cryptography, and
biomedical imaging applications. The conclusion made from the critical review analysis opens up a
new horizon for the future development of ODNPs applications.
Recent Advances in Palladium-catalyzed Borylation
Authors: Lamine Fall , Afsina C. M. A. , Archana Rajan , Anilkumar Gopinathan
Published: June 2022

The synthesis of organoboron compounds was accomplished using borylation catalyzed by palladium. This reaction is ubiquitous due to its wide-spread utility in coupling reactions and allied applications in synthesis. The attraction of borylation in organic synthesis has been attributed to moderate conditions associated with the reactions and tolerance to different types of functional groups. Their applications spread across pharmaceutical, medical, agricultural and other fields. This review summarizes the recent advances in palladium-catalyzed borylation halides and covers literature from 2012-2021.
Performance Metrics to Compare Various CO2 Reduction Processes
Authors: Lochhead Katherine , O’Hara Guenevere , Yang Dongfang
Published: June 2022

In response to the increasing concentration of anthropogenic CO2 in the atmosphere, large
research efforts have been placed on the development of suitable carbon capture and utilization technology. The transformation of CO2 into value-added chemicals is one of the most promising routes
for carbon utilization and can be accomplished by thermocatalytic, photocatalytic, electrochemical,
and photoelectrochemical methods. The advancement of this technology towards a commercial solution requires a synergistic approach, wherein members of the research community are continuously
evaluating the comparative performance of each method and adapting their research directions in response. As a result, the establishment of a universal metric for reporting the performance of thermocatalytic, photocatalytic, electrochemical, and photoelectrochemical CO2 reduction processes is critical. This work summarizes the advantages and disadvantages associated with each CO2 reduction
method and identifies their most frequently used performance metrics. Subsequently, a new performance metric, which applies to all CO2 reduction technologies, is introduced and defined as the
moles formed of the desired product per hour per accessible surface area of catalyst. Although limitations with ease of measurement exist, this work aims to demonstrate how the adoption of a universal
performance metric could help to unite the research community towards a common goal and improve
its efficiency in finding a solution to the global energy crisis.
Medicinal Importance, Pharmacological Activities, and Analytical
Aspects of Strictinin: A Mini-Review
Authors: Patel Dinesh Kumar
Published: June 2022

Background:

Plants and their derived products have been used in history as
food and medicine. Plant materials are rich sources of fiber, minerals, vitamins, and bioactive
phytochemicals, which are useful for human beings. Strictinin is an important phytoconstituent
of green tea.

Methods:

Present work mainly focuses on the biological importance, therapeutic potential,
and pharmacological activities of strictinin in medicine. Numerous scientific data
have been collected from various literature databases such as Google Scholar, Science
Direct, PubMed, and Scopus database in order to realize the health beneficial potential of
strictinin. Pharmacological data has been collected and analyzed in the present work to
find the effectiveness of strictinin against human disorders and complications. Analytical
data of strictinin has been also collected and analyzed in the present work.

Results:

Scientific data analysis revealed the biological importance of strictinin in medicine.
Scientific data analysis signified the therapeutic benefit of strictinin mainly due to
its anticancer, antimicrobial, antibacterial, antiviral, and antioxidant activity. However,
enzymatic activities, cytotoxicity, effectiveness on skin disorders, and osteogenic potential
of strictinin have also been discussed. Analytical data revealed the importance of
modern analytical techniques in medicine for the separation, identification, and isolation
of strictinin.

Conclusion:

Present work signified the biological importance and therapeutic benefits of
strictinin in medicine and other allied health sectors.
Effect of Aloe Vera Extract as Green Corrosion Inhibitor on Medium Carbon Steel in Sulphuric Acid Environment
Authors: Odhano Suhail Mashooque , Kumar Mukesh , Unar Imran Nazir
Published: June 2022

Medium carbon steel is widely consumed by various industrial sectors due to its attractive set of mechanical properties and low cost, but it experiences deterioration when exposed to a corrosive environment. In the present study, Aloe Vera plant extract was studied as a green corrosion inhibitor for medium carbon steel in an acidic medium. The presence of inhibitive compounds in Aloe Vera plant extract was determined by FTIR. Moreover, the inhibition efficiency was determined through gravimetric analysis and electrochemical analysis. The results show that the Aloe Vera plant extract provided inhibition efficiency of more than 90% in both gravimetric and electrochemical analyses. Furthermore, the shift in polarization curves depicts that this plant extract is a mixed type inhibitor acting as an anodic and cathodic inhibitor. Overall, Aloe Vera plant extract provides excellent corrosion inhibition to medium carbon steel in the H2SO4 environment and can be used as a green corrosion inhibitor for mitigating internal corrosion of pipelines and storage tanks.
Temperature Influence on the Variability and Emission of CH4 and CO2 from a Former Manchester Landfill
Authors: Nwachukwu Arthur Nwachukwu , Tyopine Andrew Aondoaver , Ephraim Bassey Edem
Published: June 2022

Analysis of datasets in time order was carried out to determine the consequence of atmospheric temperature on the changes in CH4and CO2concentrations at a former landfill site. The Gasclam(in-borehole gas monitor) was used to collect field data of CH4/CO2 concentrations and the environmental parameters. The magnitude of the relationship of ground-gas concentration and the barometric temperature was obtained by linear regression analysis. The result reveals variability in CH4 and CO2 concentrations with poor positive relationships of 0.016 and 0.014, respectively, with barometric temperature over the whole sampling period. Despite slightly improving the R2bytaking into account their concentration over single phases of upward and downward limb temperature, single phases of upward limb temperature, and single phases of downward limb temperature, their correlations remained insignificant at a 95% confidence level. The implicationis that temperature (just like pressure) is not the dominant influence on CH4 and CO2 concentrations changes at this site. Having established barometric pressure and temperature asminor controls, a recommendation was made for the establishment of other potential controls(particularly variations in the site water depth) and their degree of control.
Cloud Point Extraction for Spectrophotometric Determination of Acid Blue 29 Dye in Water Samples
Authors: Fraihat Safwan Mohammad , Amayreh Mohamad , Jaar Nayyef Al
Published: June 2022

A simple and fast Cloud Point Extraction (CPE) preconcentration of Acid Blue 29 (AB 29) dye was developed prior to its spectrophotometric determination. The suggested procedure was successfully applied for the determination of AB 29 dye in different water samples with high recoveries. Optimization of experimental conditions such as surfactant type and volume, pH, stirring, and centrifugation conditions were studied. The effect of interfering ions was also studied. The calibration curve was in the range of 0.4-10 µgmL-1 with a limit of detection and limit of quantitation of 0.35 and 1.1 µgmL-1, respectively. Furthermore, the method is free of the interference of common ions present in water.
PENGARUH PEMBERIAN DOLOMIT DAN PUPUK ANORGANIK TERDAHAP SERAPAN FOSFAT, POPULASI BAKTERI PELARUT FOSFAT DAN PRODUKSI PADI
Authors: Iswara Fiona Victor , Nuraini Yulia
Published: June 2022

Excessive use of chemical fertilizers in rice fields can reduce soil pH. Elemental P in acid soils is generally not available to plants because it is bound by Fe and Al elements; therefore, it is necessary to make an effort to optimize the availability of P in the soil by improving soil pH with the addition of dolomite lime supported by inorganic fertilizers. This study aimed to determine the effect of dolomite and inorganic fertilizers on plant P uptake, the relationship between available P and phosphate-solubilizing bacteria population, and the effect of dolomite and inorganic fertilizer application on rice yield. This study used a randomized block design with eight treatments and three replications. The results showed that the application of dolomite and inorganic fertilizer had a significant effect on plant P uptake and dry grain weight. The population of phosphate-solubilizing bacteria was positively correlated with the availability of phosphorus in the soil.
ANALISIS DAN PREDIKSI PERUBAHAN TUTUPAN LAHAN MENGGUNAKAN MODEL CELULAR AUTOMATA-MARKOV CHAIN DI DAS WAE RUHU KOTA AMBON
Authors: Rakuasa Heinrich , Salakory Melianus , Latue Philia Christi
Published: June 2022

The geographical location of the Wae Ruhu watershed is in Sirimau District, which is the sub-district with the largest population in Ambon City and is also the center of economic, educational, and industrial activities; this creates economic and population growth that has the potential to trigger land conversion around this area. This study aimed to analyze land cover changes in Ambon City in 2012, 2017, 2022 and predict land cover in 2031. This study used Cellular Automata Markov Chains modeling to predict land cover changes in 2031. The results showed that the types of land cover are built and land cover. The open area continues to increase in area, while agricultural and non-agricultural areas continue to experience a decrease in area, and water bodies do not experience a decrease or increase in area. The results of land cover predictions in 2031 showed that the built-up area is 345.79 ha, open land is 121.18 ha, agricultural land is 657.35 ha, non-agricultural land is 507.65 ha, and water bodies are 11.46 ha. The results of this study are expected to be used as a reference in making policies related to spatial planning and utilization, especially the Wae Ruhu watershed and can optimize sustainable watershed management as the first step in efforts to mitigate natural disasters.
Comprehensive analysis of the modern rolling stock efficiency in bulk cargo transportation
Authors: Vakulenko S. P. , Romenskaya M. V. , Kalinin K. A. , Shvedin K. I.
Published: June 2022

Introduction. Under the conditions of increasing containerisation of railway freight traffific, the problem of fifinding new cargo flflows suitable for transportation of freight containers or other types of intermodal freight containers on acceptable terms for both the carrier and the consignor is becoming increasingly important. Being of a fifixed size, large-capacity containers can not always meet the demands of consignors due to insuffificient carrying capacity, body volume and tariff conditions. The article examines the technical and economic effificiency of railway transport using various types of rolling stock and corresponding logistics technologies in the search for new areas for containerisation of cargo flflows.

Materials and methods. Using bulk transportation, which is weakly subject to containerisation, as example, the authors carried out an analysis of the effificiency of rolling stock depending on the type of transported bulk freight (freight density). The comparison was performed both between common types of rolling stock (conventional and increased axle load gondola) and rather rarely used types of rolling stock (articulated gondola with increased axle load, demountable railway body, open top containers and specialised bulk containers).

Results. Graphs have been plotted showing the effificiency of using each type of rolling stock, expressed through the volume of transported freight per running meter of the car and through the use of the useful volume of the rolling stock itself. The comparison proved, fifirstly, the obvious thesis about the better suitability of gondola cars for the transportation of bulk freight, and secondly, it showed a signifificant deterioration in the bulk freight transportation conditions for largecapacity containers.

Discussion and conclusion. The innovative system of demountable railway bodies demonstrates average results in the overall ranking, which indicates suffificient potential for the implementation of this logistics technology.
Conceptual model of railway car traffic organisation based on the end-to-end control of freight delivery times
Authors: Moskvichev O. V. , Mishchenko E. A. , Titarenko S. N.
Published: June 2022

Introduction. The article presents the analysis of non-compliance of delivery times of railway cargoes with the regulatory time frames. The analysis reveals a decrease in the reliability of delivery, one of the most important quality indicators. The authors assess the operation of existing automated control systems, which shows discontinuities and non-automated functions in the framework of the end-to-end control of the goods and empty cars delivery times. The purpose of the ar tic le is to propose and justify the use of a conceptual model for organising car traffic, based on end-to-end control of delivery times and risk-oriented impact on the limiting technological elements.

Materials and methods. The authors applied the methods of the modern theory of traffic management, the theory of mathematical statistics and the theory of decision making.

Results. The authors propose a conceptual model based on end-to-end control of goods delivery times and a risk-oriented impact on the limiting technological elements as a part of development of end-to-end process of the goods and empty cars delivery. The model highlights the following key provisions: control of the actual delivery time to stations by assessing the compliance with the technological standard operation times; end-to-end risk-oriented control of actual delivery times of cargo and empty cars along the entire route; providing recommendations to accelerate the advancement of the car traffic based on the technical and economic feasibility study.

Discussion and conclusion. The implementation of the proposed conceptual model enables to employ scientifically based operational decision-making to control the flow of the traffic at each stage along the route and to improve the quality of transport services and the quality of operational work of railway transport. The conceptual model can be implemented as a separate module integrated into the existing automated station control system.
Hidayet Şefkat Tuksal'ın Kadın Karşıtı Söylemin İslam Geleneğindeki İzdüşümleri adlı eserinin değerlendirilmesi / Review of Kadın Karşıtı Söylemin İslam Geleneğindeki İzdüşümleri by Hidayet Şefkat Tuksal
Authors: Aydın Zeynep Sara
Published: June 2022

Hidayet Şefkat Tuksal, Kadın Karşıtı Söylemin İslam Geleneğindeki İzdüşümleri (Ankara: Kitabiyat, 2020, 268 sayfa). ISBN 978-975-93974-2-5
Hoe promoveerde Marie Schellinck van prostituee tot onderluitenant en heldin van Napoleon?
Authors: Devriese Luc
Published: June 2022

In dit artikeltje wordt een verklaring voorgesteld voor het geloof in deze onwaarschijnlijke legende. Het verhaal ontstond en kreeg vorm in de sfeer van de negentiende-eeuwse Napoleongekte. Deze dame onderscheidde
zich, volgens haar vermoedelijk compleet gefantaseerde levensverhaal, zodanig dat ze het tot onderluitenant bracht en de hoogste Franse militaire eer verwierf: het Légion d’Honneur. Voorwaar een schitterende prestatie voor een ongeletterde vrouw uit een arm gezin die haar carrière op zeer jonge leeftijd (16 jaar) begon als prostituee. Enkele jaren geleden kreeg ze zelfs een straatnaam toebedeeld in de nieuw aangelegde Gentbrugse Bassijnwijk.
Vraag & Antwoord
Authors: Claerebaut E.
Published: June 2022

Giardia-behandeling bij honden
The effect of bridge exercises on the postural deviations and spinal cervical vertebrae deformities among wrestlers
Authors:   Department of General Courses, Faculty of Education and Arts, Northern Border University, Saudi Arabia, et al. Sabry
Published: June 2022

This study aims to identify the effect of these exercises on the bridge skill on the cervical vertebrae of the players, using modern technology by the Posture Pro 8 device, which is a high-tech devein determining the prediction of future deformations, which may occur as a result of practices and exercises that lead to the occurrence of complications, and the study sample was selected from the players of the Shooting Sports Club in Mahalla city in Egypt, and the bridge exercises were applied to that sample, and the results of the study showed no change the significant effect of bridge exercises on the occurrence of anterior or lateral deviations in the cervical vertebrae, as shown by the results of the studies. It founds that all values of the effect size in the frontal and lateral deviations are less than 80.0, which is of unremarkable effect and the total deviations between the pre and post-measurements of the group under study have an unremarkable effect as well, as the value of the rate of change ratios ranged between 0.441%.
FEATURES OF MINERAL DENSITY OF BONE TISSUE WHEN SIMULATING DIFFERENT VARIANTS OF SECONDARY OSTEOPOROSIS IN MALE OF REPRODUCTIVE AGE
Authors: Povoroznyuk V. V. , Hopkalova I. V.
Published: June 2022

The influence of sex hormone deficiency, excess of thyroid hormones and their complex action on bone mineral density parameters has been studied.

(MSCT) in male Wistar rats. It has been shown that high levels of thyroid hormones in one month of study cause a much stronger loss of BMD than

deficiency of sex hormones. High doses of thyroid hormones cause a decrease in BMD in all parts of the skeleton, with the maximum loss of BMD was

in the spine. Orchiectomy causes a maximum decrease in BMD in the hind limbs.
BETON DAYANIM ÖZELLİKLERİNİN YÜZEY TEPKİ YÖNTEMİ, GENETİK ALGORİTMA VE YAPAY SİNİR AĞLARI İLE TAHMİNİ
Authors: BAŞPINAR TUNCAY Ebru , KÖKEN Ekin , KILINÇARSLAN Şemsettin
Published: June 2022

Bu çalışmada, beton dayanım özellikleri yüzey tepki yöntemi, genetik algoritma ve yapay sinir ağları yöntemleri ile analiz edilmiştir. Altı farklı beton agregası kullanılarak küp (10x10x10 cm) ve prizmatik (15x15x60 cm) beton numuneleri hazırlanmış olup, beton tek eksenli basınç dayanımı (UCSc) ve eğilme dayanımının (FSc) tahminlenmesi için bazı tahmin modeller geliştirilmiştir. Geliştirilen modellerde beton yoğunluğu (ρc), beton agregalarının Los Angeles aşınma kaybı (LAA) ve betonlara ait P dalgası hızı (Vpc) gibi parametreler kullanılmıştır. Elde edilen modellerin performansları bazı istatistiksel göstergeler ışığında değerlendirilmiş ve genetik algoritma ve yapay sinir ağlarını temel alan yöntemlerin beton dayanım özelliklerini tahmininde başarılı bir şekilde kullanılabileceği belirlenmiştir.
CO2 DERİŞİMİNİN VE AZOT STRESİNİN CHLORELLA VULGARİS MİKROALG KÜLTÜRÜNÜN CO2 TUTMA VERİMİNE ETKİSİ
Authors: AKGÜL Gamze , VAROL Murat , ERDEM Ayça
Published: June 2022

Baca gazındaki CO2 gazının mikroalglerle tutulması küresel ısınmayla mücadele bakımından önemlidir. Bu çalışmada; farklı CO2 derişimlerinin (hacimce 400 ppm, %15 ve %90) ve azot stresinin Chlorella vulgaris mikroalg kültürünün CO2 tutma verimine etkisi incelenmiştir. Çalışmada, 5 cm iç çapa sahip, 100 cm yüksekliğinde pleksiglastan yapılmış fotobiyoreaktör kullanılmıştır. CO2 tutma verimi açısından en iyi sonucu veren CO2 derişimi belirlenmiş ve bu şartlar altında, mikroalg kültürü azot stresine maruz bırakılarak bünyesindeki lipit oranının nasıl değiştiği incelenmiştir.
Mikroalg kültürü için en iyi büyüme değerleri %15 CO2 içeren gaz karışımı altında elde edilmiştir. Fotobiyoreaktöre verilen gaz karışımındaki CO2 oranı %90’a çıkarıldığında alg hücrelerinin inhibe olduğu gözlemlenmiştir. Yüksek CO2 derişimlerinde ortamın tamponlanması ve ortama verilen CO2 derişiminin kademeli olarak arttırılması gerekmektedir. %15 CO2 derişiminde %100 azot stresinde fotobiyoreaktörde büyüme gerçekleşmemiştir. Bu nedenle azot stresi (%100 ve %75) deneylerine erlenmeyerde 400 ppmv CO2 derişimi altında devam edilmiştir. %75 azotsuz ortamda %100 azotsuz ortama göre 1,3 kat daha iyi büyüme verimi elde edilmiştir. Ayrıca, %75 azotsuz deneyde %100 azotsuz ortama göre 2,5 kat daha yüksek RuBisCO oranı belirlenmiştir. %100 azotsuz deneyde ise %75 azotsuz ortama göre 1,2 kat daha yüksek lipit oranı elde edilmiştir.
YÜKSEK HIZ VE BASINÇ ŞARTLARINDA ÇALIŞAN YÜKSEK PERFORMANSLI POLİETERETERKETON TERMOPLASTİK POLİMERİNİN AŞINMA VE SÜRTÜNME DAVRANIŞLARININ BELİRLENMESİ
Authors: ÜNAL Hüseyin , YETGİN Salih Hakan
Published: June 2022

Bu deneysel çalışmada, yüksek performanslı mühendislik plastikleri arasında yer alan poli-eter-eter-keton (PEEK) polimerinin AISI304 paslanmaz çelik diske karşı kuru kayma şartları altındaki tribolojik performansları incelenmiştir. Aşınma deneyleri, 1.77, 3.54, 5.30 ve 8.84MPa gibi yüksek basınçlarda, 0.5, 1.0, 2.0 ve 4.0m/s gibi yüksek kayma hızlarında pim-disk aşınma cihazında gerçekleştirilmiştir. Aşınma test sonuçlarına göre, artan kayma hızı ile birlikte sürtünme katsayısı ve aşınma oranı değerleri artmıştır. Düşük yük ve kayma hızlarında düşük P.V değerleri elde edilirken artan yük ve kayma hızı ile birlikte P.V faktörünün arttığı belirlenmiştir. Genel olarak deneylerde kullanılan basınç ve kayma hızı aralıklarında sürtünme katsayısının 0.17 ile 0.39 aralığında elde edilirken, aşınma oranının ise 5.2×10-15 ile 21.4×10-15 m2/N arasında değiştiği tespit edilmiştir. Deneylerde kullanılan PEEK malzemenin yüksek P.V değerlerinde abrazif aşınma mekanizması gözlenirken düşük P.V değerlerinde adhezif aşınma mekanizması gözlenmiştir.
MODELING OF SURFACE ROUGHNESS IN MILLING OF TI-6AL-4V ALLOY USING REGRESSION ANALYSIS
Authors: TOPRAK İnayet Burcu , ÇOLAK Oğuz , BAYHAN Mustafa
Published: June 2022

In this study, Ti-6Al-4V was machined under high pressure cooling conditions. Cutting parameters which were assumed as independent variables are consist of 4 different levels of cutting speed (Vc: 50-70-90-110 m/min), feed rate (f: 0.05-0.1-0.15-0.2 mm/rev) and cutting fluid pressure (P: 6-100-200-300 bar). By using SPSS 20 software, regression equations of surface roughness relative to cutting parameters was obtained as linear, second degree and linear logarithmic. Second degree multiple regression model showed best results of estimation. In the model, 95 percent of the surface roughness alterations can be explained by independent variables. Correlation between experimental data and the model was calculated as 0.975. As a result, second degree regression model proved to be successful in predicting surface roughness. The result of the study confirms the literature. When models are compared the most important parameter that affects surface roughness was observed as the feed rate. The results of the study confirms the literature.
Investigation of Microbiologically Influenced Corrosion of Concrete in Sanitary Sewer Pipes and Manholes: Field Surveys and Laboratory Assessment
Authors:   Center for Underground Infrastructure Research and Education (CUIRE), Department of Civil Engineering, The University of Texas at Arlington, Box 19308, Arlington, TX, USA 76019, Kaushal Vinayak , Najafi Mohammad ,   Center for Underground Infrastructure Research and Education (CUIRE), Department of Civil Engineering, The University of Texas at Arlington, Box 19308, Arlington, TX, USA 76019
Published: June 2022

Microbiologically influenced corrosion (MIC) of concrete in sanitary sewer pipe and manholes is the result of dilute sulfuric acid (H2SO4) dissolving the cement matrix. The acid is produced by a complex series of chemical and biochemical reactions. The objectives of this paper are: (1) to review the basic science of the MIC process starting with the various biological processes leading to the production of dilute sulfuric acid; (2) to discuss historical attempts to fortify concrete; (3) to present methods to reduce odors and corrosion; (4) to evaluate the technology behind the use of antimicrobial admixture. The literature review and authors’ on-site and laboratory investigations suggest that MIC of concrete is a complex process that involves varied surface interactions. The addition of liquid antimicrobial additive as per ASTM standard procedure shows the resistance of concrete to MIC and its direct relation with the mixing time of admixture. Many empirical inputs like corrosion areas, corrosion rates, the impact of cement, and aggregate types varying with installation and repair of sewer structures are identified. The results of this study show that with the use of antimicrobial in the concrete, there was no growth of Thiobacillus bacteria and hence no acid production. This research facilitates both the science and long-term field experiences for the use of antimicrobial technology to provide reductions in the acid causing bacteria in sanitary manholes, pump stations and other concrete structures.
Effects of Feedback From Self-Monitoring Devices on Lifestyle Changes in Workers with Diabetes: 3-Month Randomized Controlled Pilot Trial
Authors: Nagata Tomohisa , Aoyagi Sona-Sanae , Takahashi Minekazu , Nagata Masako , Mori Koji
Published: June 2022

Background

Although lifestyle interventions are useful in the prevention and management of diabetes, they can be expensive and time-consuming. There is some evidence on the effectiveness of automated mobile technology for health self-monitoring; however, few studies have used such devices in the occupational health field.

Objective

We aimed to examine the effectiveness of a digital self-monitoring device on glucose levels and activity of workers with diabetes in Japan. The primary outcomes were changes in blood glucose levels, and the secondary outcomes were changes in weight and BMI.

Methods

A 2-arm randomized controlled pilot trial was conducted with workers from 23 organizations. The intervention group (n=50) wore an armband activity monitor, a body composition monitor, and a blood pressure monitor for 3 months and received semiautomated weekly email messages tailored to their device data. The control group (n=53) engaged in no self-monitoring. Messages were developed by a physician and a dietician. Postintervention changes in blood glucose levels, weight, and BMI were compared between the intervention and control groups, using blood tests and questionnaires.

Results

At the end of 3 months, the intervention group showed significantly lower blood glucose levels (HbA1c: intervention group mean 6.4% (SD 0.3%) vs control group mean 6.6% (SD 0.3%); Cohen d=0.7, 95% CI 0.2-1.1; P=.009). There were no significant between-group differences in weight and BMI.

Conclusions

Mobile digital self-monitoring was effective in improving blood glucose levels in workers with diabetes. The use of digital health devices is a cost-effective way of implementing health self-monitoring for large numbers of individuals in the workplace. However, due to the large volume of missing values in this study, we need to be careful in interpreting the results, and well-designed intervention studies need to be conducted.

Trial Registration

University Hospital Medical Information Network UMIN000023651;
https://upload.umin.ac.jp/cgi-open-bin/icdr/ctr_view_cb.cgi?recptno=R000027244&flwp_key=1008PYbOcXKmk7CAg4Th1FWS