bluuebunny/crossref_metadata_2025 huggingface dataset:
QoS-Centric Web service Recommendation with Personalized Diversity
Authors: Kang Guosheng , Liang Bowen , Liu Jianxun , Cao Buqing , Xu Yu
Published: November 2022

With the popularity and widespread adoption of SOA (Service Orient Architecture), the number of Web services has increased exponentially on the Internet. Meanwhile, as the cost of Internet applications decreases, users tend to use online Web services for their daily business and software development needs. Under such a background, recommending desirable Web services to users which meet users’ personalized QoS (Quality of Service) requirements becomes a challenging research issue owing to the QoS preference is usually hard to provide for users, i.e., QoS preference is uncertain. To solve the problem, some recent works try to recommend QoS-diversified services to enhance the probability of fulfilling the user’s latent QoS preferences. However, the former QoS-diversified service recommendation methods recommend services with a uniform diversity degree for different users, while the diversified preference requirements are not considered. To this end, this paper proposes to mine a user’s diversity preference from the user’s service invocation history and provides a Web service recommendation algorithm, named personalized DPP (Personalized Determinantal Point Process), through which a personalized service recommendation list with preferred diversity is generated for the user. Comprehensive experiment results show that the proposed approach can provide personalized and diversified Web services on the premise of ensuring the overall accuracy of the recommendation results.
Providing a multi-stage optimization model of vehicle routing and product arrangement in Safir Etka Distribution Company
Authors: sadeghi saeed , Fallah Mohammad , Najafi Seyed Esmaeil
Published: November 2022

This paper presents a vehicle routing model with multiple warehouses and product arrangements in vehicles. Problem modeling consists of two general stages that the result of the first stage directly impacts the decisions of the second stage. Therefore, in the first stage of the problem, the main goal is the optimal arrangement of products requested by customers in packages. While in the second stage, the issue deals with the arrangement of packages (optimal dimensions obtained from the first stage) in vehicles and the optimal routing of vehicles. The goal at this stage is to reduce transportation costs, locate facilities, and select suitable vehicles. Genetic algorithms have been used to optimize the value of the first stage objective function to solve the proposed two-stage model. The weed optimization algorithm has been used to achieve the optimal value of the aim of the second stage function. The result of small sample size problem calculations is the relative difference of 0.68% of the genetic algorithm with GAMS in the first stage and the relative difference of 0.16% of the weed optimization algorithm with GAMS in the second stage; Which shows the high efficiency of the mentioned algorithms in solving the sample problem. Then 10 sample problems were designed and solved in larger sizes. The results show the high efficiency of genetic algorithms and weed optimization in solving large sample problems and case studies in a much shorter time.
Challenging the Appropriateness of Medical Fee for the Japanese Percutaneous Coronary Intervention: Is the Value of the Cardiologist’s Hard Work Properly Assessed? – Systematic Review and Field Research –
Authors: Hashimoto Satoru , Motozawa Yoshihiro , Cohen Burt , Mano Toshiki
Published: November 2022

Background
In Japan, technical fees in reimbursement are considered not to reflect in actual medical costs, and medical procedures may often result in a deficit of the hospital. This systematic review and field research aimed to investigate the appropriateness of the reimbursement for percutaneous coronary intervention (PCI) as an example of the controversial issue associated with medical expenses in Japan.
Methods
We investigated the validity of the medical fee for PCI from two perspectives: the total cost of PCI in Japan compared with those in other countries, such as the United Kingdom, the United States of America, and Australia, and the appropriate cost of PCI calculated using 1) the costing calculation, 2) book-building, and 3) lost profit methods to investigate the technical fee, which is part of the medical fees.
Results
To compare the PCI cost between other countries and Japan, we searched PubMed and Google Scholar to extract articles that demonstrated PCI cost in the target countries from January 2018 to August 2022. Research reports as well as government-provided sources in each country were also searched using the Google search engine, which finally led to the extraction of eight abstracts. The results indicated that the total cost of PCI for acute myocardial infarction (AMI) was higher in Japan than in other countries; however, no difference was observed for unstable angina (UA). The average costs of technical fees calculated according to three methods were \772,186 for AMI-PCI and \566,688 for UA-PCI, which were higher than the existing reimbursement prices of \343,800 and \243,800, respectively.
Conclusions
Although the total PCI cost in Japan was not different from those in other countries, the technical fees of PCI reimbursed in FY2022 did not even come close to covering the cost.
The effect of the COVID-19 pandemic on going out, a critical activity of daily living, in the general elderly population
Authors: Uematsu Masato , Tamai Koji , Terai Hidetomi , Iwamae Masayoshi , Takahashi Shinji , Katsuda Hiroshi , Shimada Nagakazu , Habibi Hasibullah , Nakamura Hiroaki
Published: November 2022

Background
During the coronavirus disease 2019 (COVID-19) pandemic, home quarantining and refraining from non-essential and non-urgent outings were enacted. The exact impact of the response to the COVID-19 pandemic on the activities of daily living (ADLs) in the general elderly population remains unclear. Thus, this study aimed to investigate the impact of the COVID-19 pandemic on the ability to go out, which is an important part of ADL, in the general elderly population.
Methods
A cross-sectional survey was conducted at a COVID-19 vaccination center in Habikino City, Osaka, Japan. Participants, aged ≥ 65 years, completed a questionnaire surveying general information, ADLs, presence of musculoskeletal symptoms, and quality of life at pre- and post-outbreak. Participants were classified into two groups based on their pre- and post-outbreak ability to go out: the Able-Able group comprised those who were able to go out before and after the pandemic, while the Able-Disabled group comprised those who had deteriorated in their ability to go out over the course of the pandemic. Univariate and multiple logistic regression analyses were performed to identify factors associated with the Able-Disabled group.
Results
Among 33,191 elderly people living in the city, 12,088 (36.4%) participated in this study. In total, 341 (2.8%) people could not go out even pre-pandemic and 346 (2.9%) patients lost the ability to go out during the course of the pandemic. Independent risk factors for membership in the Able-Disabled group were older age, male sex, high body mass index, decreased daily exercise or no exercise habits, and new-onset musculoskeletal symptoms (back and joint pain).
Conclusions
The current study included 36% of the general elderly population living in a Japanese city. In total, 2.9% had lost the ability to go out post-outbreak, and the total number of elderly people unable to go out had doubled within 2 years after the start of the pandemic. A vicious cycle could occur in which ADLs decline due to decreased physical activity and reduced frequency of outings. It may be important for elderly people to avoid decreasing the opportunities for daily exercise and going out to maintain their ADLs.
Occurrences, Potential Sources and Risk Impacts of Organochlorine Pesticides in the main urban Soil of Changchun, Northeast China: a case study
Authors: Zhao Wei , Lu Jilong , Lai Yawen , Lan Tian , Guo Jinke , Fan Yuchao , Hou Yaru
Published: November 2022

48 surface soil samples from the main urban areas in Changchun, Northeast China were analyzed for 18 organochlorine pesticides (OCPs) with the aim of elucidating their contamination status, distribution characteristics, influencing factors, and potential risks in this urban region. The total concentrations of OCPs ranged from 15.63 to 92.79 ng/g, with the geomean of 36.46ng/g. HCHs, DDTs, and Chlordanes were the most dominant OCPs, with γ-HCH and p,p'-DDT being the predominant isomer. Higher concentrations of OCPs mainly concentrated in the northeast and southwest of Changchun city and the artificial influences contributed to the fate of OCPs in the soils. The residues of OCPs were mainly derived from the historical application of the technology DDT, dicofol, and lindane. Pearson’s correlation analysis indicated that TOC was a key factor controlling OCPs accumulation. The data analysis based on the soil quality guidelines (SQGs) suggested that the presence of DDTs, lindane, and heptachlor may pose a certainly toxic ecological threat to the soil organisms. The evaluation results of incremental lifetime cancer risk (ILCR) showed that the cancer risk of OCPs to the posed population was low, while some specific locations with high OCPs residues ought to be a cause for concern.
Identification of ceRNA-based H19/SIX4 regulatory axis as a prognostic biomarker for colorectal cancer via high throughput transcriptomic data
Authors: Zhang Fanqin , Wu Chao , Zhang Jingyuan , Huang Zhihong , Stalin Antony , Shi Rui , Huang Jiaqi , Zhai Yiyan , Chen Meilin , Liu Pengyun , Zhou Wei , You Leiming , Wu Jiarui
Published: November 2022

Colorectal cancer, a common digestive system malignancy, is a leading cause of cancer-related deaths worldwide and has become a major public health problem. Molecular research can provide a large amount of new information for cancer treatment and new drug development. The ceRNA (competing endogenous RNAs) hypothesis reveals a mechanism of RNA interactions. This research aims to construct a ceRNA regulatory network in colorectal cancer to identify potential prognostic biomarkers associated with COAD. Expression profiles of COAD were downloaded from The Cancer Genome Atlas (TCGA). We used R software for differential analysis and enrichment analysis and then identified the subcellular localization of lncRNAs using the LncATLAS and LncACTdb database. Next, we constructed ceRNA networks using Cytoscape software and used survival analysis to identify the ceRNA axis with prognostic significance. The results showed that the H19/miR-193b-3p/SIX4 ceRNA network was associated with COAD prognosis. The correlation between SIX4 expression and tumor immune infiltration was explored via TIMER. The GeneMANIA database was used to obtain proteins interacting with SIX4, and these proteins were subjected to GO and KEGG enrichment analysis, which showed that these proteins are involved in “Transcription misregulation in cancer” of tumors. Then, the relationship between SIX4 expression and prognosis was analyzed using univariate cox regression analysis, plotting forest plots, and plotting K-M curves. The expression and correlation of SIX4 with tumor mutational burden (TMB), microsatellite instability (MSI), DNA mismatch repair genes (MMRs), and methyltransferases in pan-cancer were analyzed. The results indicated that the H19/miR-193b-3p/SIX4 ceRNA axis probably influences the alteration of the tumor immune microenvironment. In addition, the GSEA results showed that high expression of SIX4 was mainly associated with the “Notch signaling pathway”.
Automatic Detection, Quantification and Classification Method for Plant Foliar Diseases Based on Deep Learning
Authors: Ji Miaomiao
Published: November 2022

Accurate evaluation of percent severity of visible symptoms or injuries caused by fungal diseases on plant organs is not only essential in plant health and epidemics research but also critical for breeding, assessment of germ plasm and genetic studies of resistance. In this paper, we have introduced a series of effective pixel-level semantic segmentation models used for automatic detection, quantification and classification of plant foliar diseases based on convolutional neural networks (CNNs). The proposed scoring and grading system of plant diseases involves several steps, which entails: dataset creation, image segmentation, statistical calculation and table query operation. In this study, we train four state-of-the-art CNN-based semantic segmentation models including PSPNet-ResNet50, UNet-ResNet50, BiSeNet-ResNet50 and DeepLabV3Plus-ResNet50 for pixel-level predictions in images of individual leaves exhibiting pathological lesions caused by fungal disease: potato late blight fungus and grape black measles fungus, which serve as case studies. Experimental results report that DeepLabV3Plus-ResNet50 is a more efficient model for plant foliar diseases severity evaluation and an overall classification accuracy of 92.00% for potato disease divided into 5 levels and 94.67% for grape disease divided into 4 levels on the hold-out test dataset is obtained.
WITHDRAWN: Application of object detection algorithm based on deep learning in classification of wild ginseng grades
Authors: GUO Boqiu , JIN Hua , CAI Yong , WU Lunpeng , SUN Xianli , CHEN Fan , CHENG Ziyu
Published: November 2022

Object detection based on deep learning has an excellent effect on wild ginseng classification. In recent years, the Object detection algorithm has been widely used in the classification research of various leaf plants, while the field of wild ginseng generally uses relatively backwards manual identification methods. The identification of wild ginseng by artificial methods are of low efficiency, subjectivity and poor accuracy. In order to solve this problem, this paper proposes a new structure based on PP-YOLO tiny object detector, namely PP-YOLO tiny BiFPN*, improving the backbone network and replacing its neck with the bidirectional feature pyramid network to enhance feature extraction. Combined with embedded devices, Paddle-Lite framework and OpenCV technology, an auxiliary wild ginseng grade classification system based on the deep learning algorithm and embedded devices is designed and implemented. In the test environment, the PP-YOLO tiny BiFPN* model obtained in the first and second grade wild ginseng classification precision of 99.61% and 99.72%, recall of 99.72% and 99.61%, the classification accuracy of the whole wild ginseng sample has reached 99.66%. The model size is only 2.27MB, and the processing speed of each image is 0.266 seconds per image, which is suitable for working in the environment of limited resources, and opens up a new idea for the intelligence classification of wild ginseng.
A bridge between Vector Bundle Theory and Nonlinear Spectral Theory
Authors: Sampedro Juan Carlos , López-Gómez Julián
Published: November 2022

This paper establishes some hidden connections between the theory of generalized algebraic multiplicities, the intersection index of algebraic varieties, and the notion of orientability of vector bundles. The novel approach adopted in it facilitates the definition of several invariants closely related to the first Stiefel-Whitney fundamental class through some path integration techniques.
Recombinant Bacillus subtilis expressing a fungal phytase as a probiotic additive in the diet of Pacific white shrimp Litopenaeus vannamei
Authors: Medeiros Luiza , Nornberg Bruna , Azevedo Raíza , Cardoso Arthur , Rosas Victor Torres , Tesser Marcelo Borges , Pedrosa Virgínia F. , Romano Luis A. , Wasielesky Wilson , Marins Luis Fernando
Published: November 2022

Phosphorus is an essential mineral present in the vegetable matter in the form of phytate, which is considered an antinutritional factor. Phytate can be degraded by phytases, which have been used in commercial feeds. However, these enzymes undergo costly isolation and purification processes. In the present study, a genetically modified (GM) Bacillus subtilis strain that expresses a fungal phytase was used as a feed additive. The GM probiotic was added to the commercial feed of shrimp Litopenaeus vannamei and its effects on zootechnical performance, proximate composition of muscle, lipid concentration in hepatopancreas and expression of genes related to digestion, amino acid metabolism and antioxidant defenses were analyzed. Although the genetically modified probiotic had no impact on growth parameters, there was a 39% increase in phosphorus content in muscle. In addition, genes related to digestion were downregulated in shrimp hepatopancreas, as well as an increase in lipids in this tissue. These results demonstrates that the GM probiotic increased the efficiency of the use of plant-derived phosphorus, which may imply a decrease in the addition of this element in the diets, as well as minimizing the impact of shrimp farms on the eutrophication of adjacent ecosystems.
A chronic high fat diet does not exacerbate muscle atrophy in fast-twitch skeletal muscle of aged mice
Authors: Tagawa Tsutomu , Eshima Hiroaki , Kakehi Saori , Kawamori Ryuzo , Watada Hirotaka , Tamura Yoshifumi
Published: November 2022

Obesity and aging reduce muscle mass and leads to deficits in muscle maintenance, but it is unknown whether obesity additively accelerates muscle wasting in the setting of aging. The present study investigated morphological characteristics in fast-twitch dominant muscle of mice fed a low-fat diet (LFD) or a high-fat diet (HFD) for 4 or 20 mo. The fast-twitch extensor digitorum longus muscle was isolated, and the composition of muscle fiber type, individual muscle cross-sectional area (CSA), and myotube diameter were measured. Increased the percentage of type IIa myosin heavy chain (MHC) fibers, whereas decreased type IIB MHC in both HFD protocols. The CSA and myofiber diameter were lower in both 20 mo LFD and HFD fed mice compared to 4 mo mice, but there were no differences between 20-mo LFD and HFD-fed mice. These data suggest that long term of HFD feeding does not aggravated muscle wasting in fast-twitch dominant muscle of aged mice.
Dihydrotestosterone Downregulates the Inflammatory Response in Human Conjunctival Epithelial Cells
Authors: Zibandeh Noushin , Kusan Eda , Karslioglu Melisa Zisan , Tas Ayse Yildiz , Sahin Afsun
Published: November 2022

Purpose: The aim of our study is to investigate the effect of dihydrotestosterone (DHT) on the inflammatory response of the human conjunctival epithelial cells (HConjECs) under stress conditions.
Methods: HConjECs were cultured with or without 10−8 M dihydrotestosterone (DHT) in normal osmolar conditions for 48 hours. Then, the media was changed to a higher osmolarity for different time points to demonstrate the effect of hyperosmolar stress conditions on both treated and untreated cells. After the cell pellet was lysed with radioimmunoprecipitation assay (RIPA), phosphorylated and nonphosphorylated forms of p38 kinase, extracellular signal-regulated kinase 1/2 (ERK1/2), and c-Jun N-terminal kinase 1/2 (JNK1/2) were analysed by western blot. The gene expressions of TNF-α, IL-1β, and IL-8 were measured with a real-time polymerase chain reaction. The cell viability was checked with Annexin V/PI.
Results: Pretreatment with 10−8M DHT inhibited the hyperosmolarity-induced expression of TNF-α and IL-1β. Expression of p-P38 was inhibited with DHT pretreatment but only DHT-pretreated HConjECs suppressed p-ERK up to 30 minutes after hyperosmolar stress. DHT pretreatment inhibited apoptosis in HConjECs.
Conclusion: These data revealed the potential importance of DHT in the treatment of DED. Furthermore, our findings may contribute to a better understanding of how sex hormones affect different ocular surface diseases and their potential for therapy.
A Reinforcement Learning Framework Based on Genetic Algorithm for Annotating Arabic Text in Natural Scene Images
Authors: Boukthir Khalil , Haddad Lobna , Hamdani Tarek M. , Alimi Adel M.
Published: November 2022

Scene text recognition is an important part of scene understanding systems, hence lately the problem has gotten increasing attention. The popularity of this issue can be attributed to the numerous potential applications and future challenges. However, the scientific community has long concentrated on the CNN (Convolutional Neural Network) models in training phase, disregarding those that are preliminarily processes, such as the annotation of datasets. The objective of this work is to develop a reinforcement learning semi-automatic Arabic text annotation system in natural scene images based on genetic algorithm. In this paper, we use reinforcement learning to enhance CNN network based annotation and we validate our system on our TSVDR (Tunisia Street View Dataset for Arabic Word Recognition) dataset, EvArEST dataset and the synthetic data. Our system is shown to reduce significantly the number of required training samples and to minimize the annotation time to less than 1/4.
Metabolic changes of endothelial cells in post-burn patients using UHPLC-MS/MS
Authors: Wu Fangqin , Yan Zhuoxian , Ran Yanqin , Wang Mengna , Yang Sifan , Huang Mitao , Zhou Situo , Zhang Pihong , Jiang Bimei , Liang Pengfei
Published: November 2022

INTRODUCTION Monitoring metabolic biomarkers could be used as an effective tool for post-burn patient diagnosis and repair.
OBJECTIVE. Endothelial cells play an important role in repair after burns. However, little research has been done on this. We aim to discover predictive biological endothelial cell markers and study biomarker-related metabolism.
METHODS After establishing a thermal injury model using endothelial cells. We examined the metabolic changes 48 and 72 h after burn using liquid-phase mass spectrometry and endothelial cell models derived from heat treatment.
RESULTS A total of 365 metabolites in 12 samples were analyzed using liquid chromatography–mass spectrometry. Among these, univariate analysis after the false discovery correction showed eight concentrations in each time period changed significantly with time (P ＜0.05). The 48-h post-burn was characterized by a decreasing trend in the levels of six metabolites including deoxycholate, glucose 1-phosphate, glucose 6-phosphate, mannose 6-phosphate, histidine, and 1-methyl-2-pyrrolidone, and Metabolites with significantly increased levels were Sambucinol, Flufenacet. The levels of metabolites such as azelate, 1-methyl-2-pyrrolidone, guanosine monophosphate, xanthosine monophosphate, cytidine, and flufenacet decreased significantly, while the level of dibutyl phthalate showed an increasing trend after 72 h. Metabolic pathways such as Starch and sucrose metabolism and purine metabolism are greatly affected.
CONCLUSION Our study shows that metabolomic signatures of heat-injured endothelial cells were found to correlate with their burn time, suggesting that metabolomics may have the potential to develop new diagnostic and therapeutic approaches for burns.
Existence and regularity results for a degenerate elliptic nonlinear equation on weighted Sobolev spaces
Authors: Kalleji Morteza Koozehgar , Alimohammady Mohsen , Cattani Carlo
Published: November 2022

This paper deals with the existence of many solutions a degenerateweighted elliptic equation which its the number of solutions dependon degeneracy term $a$ i.e., the number of subdomains of$\Omega\setminus a^{-1}(0)$ whose boundary is made by submanifoldswith 1-codimension. Moreover, by the Ljusternik–-Schnirelmanprinciple, we would study the corresponding eigenvalue problem andobtained the nonnegative eigenvalues sequence of main problem.Finally, we will discuss of the regularity of the solutions on$C^{1,\alpha}(\Omega).$
Advertising expenditures and dividend policy: Evidence from an emerging market
Authors: Farooq Omar
Published: November 2022

The aim of this paper is to document the effect of advertising expenditures on the dividend policies adopted by non-financial firms from India firms during the period between 2000 and 2019. Our results show that advertising expenditures have a significantly positive impact on dividend payout ratios. Our results are robust across various proxies of advertising expenditures and dividend policies. These results are consistent with the argument that advertising expenditures improve the information environment of firms by increasing their visibility among stock market participants. Superior information environment makes expropriation technology expensive and leads to greater sharing of corporate profits. Furthermore, our findings also show that dividend payouts are more valuable for firms that incur low advertising expenditures. It indicates that dividend payouts improve firm value more when information environment is opaque.
Copper Nanostructured biohybrid material as broad-spectrum antiviral agent and its application as coating surface material
Authors: Losada-Garcia Noelia , Vazquez-Calvo Angela , Alarcon David , Abian Olga , velazquez-campoy adrian , Domingo-Calap Pilar , Alcamí Antonio , Palomo Jose M.
Published: November 2022

Respiratory pathogens kill more people than any other infectious agent each year worldwide. The development of novel economically-friendly, sustainable and highly efficient materials against viruses is a major challenge. Here we describe a nanostructured material composed of very small crystalline phosphate copper nanoparticles synthesized based on a new biohybrid technology that employs the use of a biological agent for its formation. This aqueous and room temperature stable material showed high virucidal activity against different viruses, including SARS-CoV-2. In addition, this new material has been successfully scaled-up and has been shown to have multiple applications as a coating agent on different surfaces of different composition (cotton, polyester, cellulose, paint, etc.). Interestingly, this nanomaterial showed antimicrobial-properties for the manufacture of antiviral face masks, maintaining high virucidal efficacy and stability, even after several washing cycles allowing its reuse.
CONSTRUCTİON SECTOR EMPLOYEES' ATTİTUDES TOWARDS OCCUPATİONAL HEALTH AND SAFETY: A RESEARCH İN TEKİRDAG / ERGENE DİSTRİCT
Authors: YÜKSEL Ahmet , GÜNAYDIN Davuthan
Published: November 2022

İş Sağlığı Ve Güvenliğine İlişkin Tehlike Sınıfları Listesi Tebliği:ne göre İnşaat sektörü ölümcül iş kazalarının en çok yaşandığı sektördür. Bu nedenle de çok tehlikeli işler kategorisindedir. Çalışma ortamından kaynaklanan risklerin yanı sıra sektörde çalışanların eğitim seviyelerinin düşük olması, taşeron uygulaması ve kısa süreli çalışmanın yaygınlığı ile iş güvenliği uzmanlarının görevlerini yerine getirmesinde yaşanan sorunlar, kaza riskini arttırmaktadır. Bu çalışmada Tekirdağ/Ergene İlçesinde faaliyet gösteren inşaatlarda çalışan 40 işçi ile görüşmeler gerçekleştirilmiştir. Araştırmada çalışanların İş Sağlığı ve Güvenliğine (İSG) yönelik bilgi, algı ve tutum seviyeleri ölçülmeye çalışılmıştır. Araştırmada nitel analiz yöntemi kullanılmış, bulgular MAXQDA 2018 programı kullanılarak analiz edilmiştir. Bulgular; inşaat sektörü çalışanlarının bilgi, algı ve tutum seviyelerinin düşük olduğunu göstermektedir. Bu durumun temel nedenleri olarak da eğitim düzeyinin düşük olması, iş kaybı korkusu, çalışanların özgüvenleri, İSG eğitimlerinin yetersizliği ve iş kazalarına kaderci yaklaşım olduğu tespit edilmiştir
Examining the Impact of Covid-19 On The Financial Sustainability of the Social Security System by TOPSIS Method
Authors: SEVİM Ferit , AĞIRBAŞ İsmail , YILMAZ Gökhan
Published: November 2022

The Covid-19 pandemic has negatively affected social security systems already experiencing financial sustainability problems. In this study, the effect of the COVID-19 pandemic on the financial sustainability of the system was tried to be revealed with evidence-based data using a multi-criteria decision-making method. In the study, the social security system’s sustainability and annual performance levels were evaluated by technique for order preference by similarity (TOPSIS) method, which can be applied to different workplaces. In the study, 9 different criteria affecting the sustainability of the social security system were used. The data were obtained from the Social Security Institution Data Practice database. Data between 2014 and 2021 were included in the study. The findings of the study show that there is an increase in the invoice amount per application and the invoice amount per prescription in private hospitals, public secondary and tertiary hospitals, and university hospitals. The findings show that the Ci value closest to the ideal value is in 2015 (Ci2015=0,9318) and the farthest Ci value belongs in 2020 (Ci2020=0,1404). While the obtained Ci values were found to be within a certain range, it was determined that the pandemic in 2020 caused a major breakdown in the direction of the negative ideal. As a result, the sustainability of the social security system, which is currently experiencing problems, and the economic and social problems experienced globally with the pandemic have reached an even more important critical threshold for health politicians.
Who Does Pinocchio Think It Is?
Authors: Çalcı Sercan
Published: November 2022

U ovom članku zamišljam scenu u Platonovoj spilji gdje Gilles Deleuze i Félix Guattari susretnu Pinocchija, najpoznatijeg lutka. Želim istražiti oblike otpora stvorene izričajima Tijela bez organa tijekom postupka Pinocchijeva oblikovanja te objediniti elemente koji potkopavaju pedagogijsku uzročnost uspostavljenu između govorenja laži i izduljenja nosa, da bih pokazao da je moguće drugačije tumačenje Pinocchijevih pustolovina. Nadam se takvo čitanje postići demonstracijom stalnog sukoba dvije logike Pinocchijevih pustolovina: logiku kazne i logiku simptoma. Ovo se istraživanje također može čitati kao pripremanje mogućeg strateškog plana bijega iz Platonove spilje za Pinnochija, Deleuzea i Guattarija.
The Metaphysics of Immorals – Naturalism, Materialism and Atheism of Marquis de Sade
Authors: Škorić Marko , Kišjuhas Aleksej
Published: November 2022

U ovom se članku argumentira da je Marquis de Sade izvorniji i važniji filozof Prosvjetiteljstva no što se inače smatra. Tvrdimo da je de Sade i za suvremeno vrijeme važan autor i naturalistički mislitelj vrijedan pozornosti s obzirom na suvremenu znanost, religiju, (homo)seksualnost, političko nasilje i prevladavajuće sociokulturne norme. Da bismo dokazali ove tvrdnje, iscrpno analiziramo de Sadeove filozofije naturalizma i materijalizma, tj. njegovu metafiziku i radikalnu etiku »imoralnosti«, temeljenu na viđenju (ljudske) Prirode kao jedinog organizirajućeg, stvaralačkog i uništavalačkog principa. Nadalje, opisujemo njegove ateističke i antiteističke argumente koje dosljedno koristi da bi odbacio mogućnost Boga i svih natprirodnih bića, povezane s njegovim društvenim i političkim kriticizmom društva temeljenog na vjeri. Stoga, ocrtavamo filozofijske argumente koje su ga učinile kontroverznim, nečasnim i odbačenim misliteljem i koji su ga društveno otklonili od prevladavajućeg filozofijskog miljea. Također argumentiramo u korist mogućnosti da zaslužuje istaknutije mjesto u povijesti filozofije koje nije kongruentno s različitim »rehabilitativnim« i »revizionističkim« narativima vezanim uz de Sadea kao ranog prvaka Protuprosvjetiteljstva, protuznanosti i postmodernizma.
The Mediating Role of the Body in Structuralism and the Phenomenological Tradition
Authors: Todorović Tanja
Published: November 2022

Fenomen tijela zanemarivan je i stavljan u najniže hijerarhijske razmjere kroz gotovo čitavu filozofsku tradiciju. To je posebno uočljivo u problemima modernoga dualizma, koji je imao metodološke teškoće prilikom pomirenja jaza između duše i tijela. Iako smješten najniže na ontološkoj ljestvici, fenomen tijela u antičkoj je filozofiji igrao značajnu ulogu, posebno u poetičkoj i praktičkoj filozofiji. Njemački idealizam koji, na čelu s Hegelom, pokušava prevladati suvremeni dualizam i usvojiti klasičnu antičku dijalektiku, ponovno potvrđuje važnu ulogu tjelesnog fenomena pokazujući njegovo posredničko mjesto kako na polju teorijskih istina, tako i na polju objektivnoga duha. Iako je suvremena filozofija napravila pomak od idealističke logike, ovaj članak naglašava da je fenomenološka metoda, čiji je osnivač Husserl, također afirmirala fenomen tijela. Razlikujući perceptivnu (Gegenwärtigung) i imaginacijsku (Vergegenwärtigung) svijest, Husserl nam omogućava pristup fenomenu tijela na različite načine, pokazujući njegovu neovisnost u polju estetike. To je utjecalo na strukturalističku tradiciju, posebno Rancièrea, koji razvija slobodno polje prakse kroz pojam senzibilnoga svijeta. Taj je pojam predstavljen na temelju medijacijske uloge tijela, čime se omogućuje polju estetike da se pojavi kao slobodan režim djelovanja.
2-Group symmetries and M-theory
Authors: Del Zotto Michele , García-Etxebarria Iñaki , Schäfer-Nameki Sakura
Published: November 2022

Quantum Field Theories engineered in M-theory can have 2-group
symmetries, mixing 0-form and 1-form symmetry backgrounds in non-trivial
ways. In this paper we develop methods for determining the 2-group
structure from the boundary geometry of the M-theory background. We
illustrate these methods in the case of 5d theories arising from
M-theory on ordinary and generalised toric Calabi-Yau cones, including
cases in which the resulting theory is non-Lagrangian. Our results
confirm and elucidate previous results on 2-groups from geometric
engineering.
RISK FACTORS AND CLINICAL PRESENTATION OF VERNAL KERATOCONJUNCTIVITIS IN PATIENTS VISITING THE OUTPATIENT DEPARTMENT AT A RURAL TERTIARY CARE HOSPITAL
Authors: Venkateswaran Shwetha , Badhe Kishor , Wable Shraddha
Published: November 2022

Introduction: Vernal keratoconjunctivitis (VKC) is an allergic eye disease. It is a bilateral, seasonal, external ocular inflammatory disease of unknown cause. The clinical picture of VKC is characterized by ocular symptoms such as pruritus, tearing, burning, foreign body sensation and photophobia. There are three clinical forms: Palpebral, bulbar and mixed. Risk factors include allergic tendencies, family history of atopy, tropical climate. There is male preponderance to this condition. Aims/objectives:To study the known risk factors predisposing to and clinical presentation of Vernal keratoconjunctivitis in patients at our rural tertiary care hospital. Materials and Methods: We included 40 patients of both genders who came to the outpatient department of our rural tertiary health centre with signs and symptoms of VKC and excluded patients with other ocular surface disorders. Results: Out of 40 study participants, 26 (65%) were male and 14 were female. Majority of patients (55%) visited the OPD in the summer season.There was a significant history of other atopic manifestations, such as eczema or asthma, in 55% of patients. A family history of atopy was found in 19 (47.5%) patients.It was bilateral in 95% (38) patients.The predominant form seen in our RHTC was palpebral in 25 patients (62.5%), followed by mixed (25%) and bulbar (12.5%). Commonest symptom was itching, seen in 70% of patients,Diminution of vision was seen in 5% of patients due to corneal scarring and Shield ulcer. Signs included papillae, limbal thickening, Horner Trantas spots, punctate epithelial erosions or keratitis, Shield ulcers. Conclusion: VKC is a bilateral, allergic, seasonal, external ocular inflammatory disease of unknowncause. It involves the conjunctiva and can involve the cornea and eventually lead to vision threatening complications.
Inventarisasi Jenis Paku Terestrial (Pteridophyta) Di Kawasan Wisata Air Terjun Tujuh Tingkat Desa Selamat Kecamatan Tenggulun Kabupaten Aceh Tamiang, Aceh
Authors: Ramadani Risa , Navia Zidni Ilman , Persada Andri Yusman
Published: November 2022

The area of the Seven Waterfalls at the Village Level Selamat Tenggulun District has an area that is still beautiful, very supportive for the growth and development of terrestrial nails. This study aims to determine the types of terrestrial ferns in the Seven Level Waterfall Area. The research was conducted from January to May 2020 in the Seven Waterfall Area at Selamat Village Level, Tenggulun District, Aceh Tamiang Regency using the roaming method. The results showed that in the Seven Level Waterfall Area there were as many as 20 species, from 3 nations, 9 tribes, 17 genera of ferns and lived terrestrial, namely Dicranopteris linearis (Burm. F.) Underw, Deparia petersenii (Kunze) M. Kato , Diplazium esculentum (Retz) Sw, Diplazium sandwichianum (C. Precl) Diels, Pleocnemia irregularis (Burm. F.), Blechnum orientale L, Stenochlaena palustris (Burm. F.), Nephrolepis cordifolia (L.) C. Precl, Nephrolepis exaltata (L.) Schott, Drynaria quercifolia (L.) J. Sm, Microsorum scolopendria (Burm. f.) Copel, Adiantum trapeziforme L, Pityrogramma calomelanos L.Link, Pteris biaurita L, Tectaria acerifolia RC Moran, Tectaria decurrens (C. Presl) Copel, Heterogonium pinnatum (Copel.) Holttum, Christella dentata (Forssk) Brownsey Jermy, Cyclosorus heterocarpus (Blume) Ching and Selaginella sp .
Fenologi Bunga Zinnia sp dan Potensinya Sebagai Refugia Pada Tanaman Cabai (Capsicum annum)
Authors: HARAHAP WAHYUNI UMAMI , Fadhillah Wizni , Intan Dian Retno
Published: November 2022

Budidaya tanaman cabai di Indonesia saat ini sangat bergantung terhadap penggunaan pestisida sintetik.  Pestisida sintetik sangat buruk terhadap kelestarian lingkungan seperti berkurangnya jumlah dan jenis musuh alami. Kondisi tersebut mendorong penemuan teknik pengendalian hama dan penyakit yang lebih ramah lingkungan seperti penggunaan refugia. Refugia yang sering digunakan adalah Zinnia sp. Namun morfologi Zinnia sp belum banyak diketahui terutama tentang penologi bunga sehingga sulit menentukan waktu penanaman yang tepat agar efektif dalam mengendalikan hama. Hal ini yang menjadi dasar dilakukannya penelitian penggunaan refugia Zinnia sp pada tanaman cabai.  Penelitian ini dilakukan dengan penanaman refugia Zinnia sp sebanyak 20 tanaman di setiap pinggir bedengan. Pengamatan dilakukan dengan mengamati perkembangan bunga Zinnia sp setiap hari serta mengidentifikasi hama dan musuh alami.  Berdasarkan hasil pengamatan diketahui serangga menyukai bunga Zinnia sp pada fase X sampai XII. Hama yang ditemukan pada lahan adalah orong-orong (Gryllotalpa sp.), lalat pengorok daun (Liriomyza sp.), kutu kebul (Aphis craccivora), trips (Thrips spp.), tungau (P. latus), lalat buah (Bactrocera spp.). Musuh alami  yang ditemukan pada lahan adalah Hemiptarsenus varicornis, Eriborus argenteopilosus, Menochilus sexmaculatus. Kesimpulan yang dapat diambil dari penelitian ini adalah Zinnia memiliki potensi yang tinggi untuk digunakan sebagai refugia dan penanaman Zinnia sp sebaiknya dilakukan satu bulan lebih awal dari penanaman cabai.
Seyma-Turbino Metalworking and Microtechnics: A Game of Scale
Authors: Mikhailov Yu. I.
Published: November 2022

Along with ordinary utilitarian things, Seymа-Turbinо casters made technically advanced products devoid of pragmatic functions. Miniature copies of full-size prestigious products were found in graves and shrines. Probably, communities of metalworkers treated these miniature tools as material symbols of their group identification. Numerous finds made in Petrovka, Sintashta, and Seymа-Turbino archeological sites mean that these metal miniatures were in high demand. Low-rank metal workers might have been buried with miniature samples of less technologically advanced tools. Full-size sophisticated tools, as well as their miniature copies in children's graves, could symbolize individual status. Miniature artistic castings that served as pommels on massive curved knives marked the prestigious status of this type of weapon and symbolically equated it with the Tools of the Creation. The figurines that adorned the Seyma-Turbino weapon not only emphasized its impressive size, but also gave the owners of these perfect products a higher social status. The miniature sculpture, which adorned only some of the Seyma-Turbino metal products, individualized serial samples. Thus, the microtechnics reflected not only the new possibilities of Seyma-Turbino metalworking, but also the regulatory requirements for the design of prestigious metal products. The renewal of the material ambiance was caused by the spread of serial products, the so-called quick things. It reflected the need to strengthen the connection between the owner and the possession, which was inherent to individual single-piece production
The Social Structure of the Pskov Province in Archival Materials from the 1760s
Authors: Goncharova E. V. , Pavlova M. M.
Published: November 2022

The present research featured the social structure of the Pskov Province in the 1760s. The cities of Pskov and Velikiye Luki were the two most densely populated areas in the region, but this study also covered the less populated Gdov urban area. The author relied on church records, e.g. confession lists and metric books, from the State Archive of the Pskov Province. The research also included original and scientifically processed audit descriptions. They proved to be a novel and extensive source of data that made it possible to describe the demographic and social structure of pre-revolutionary provincial Russia. The analysis revealed the quantitative, gender, income, and religious characteristics of the local population in the 1780s. The population of the Pskov Province was mainly represented by Russians peasants, especially in the area of Velikiye Luki. Velikiye Luki and Pskov had an exceptionally large number of peasant city-dwellers, which was untypical for the provincial society of that time. In general, the 1760s saw a considerable growth of taxable population in the Pskov Province.
Memory Policy in the Republic of Sakha (Yakutia) in the XXI Century
Authors: Kirchanov M. V.
Published: November 2022

This article features the contemporary politicy of memory in the Republic of Sakha (Yakutia), as well as the role of historical politics in the development of national memory and identity. Methodologically, the research relied on the principles of the memorial turn and memory policy within the paradigm of intellectual history and the history of ideas. The novelty of the study lies in the analysis of common and unique features of historical politics as a politics of memory in Yakutia because non-European cultures still remain underrepresented in historiography. The author also analyzed the role of state strategies and media actors in the development of collective historical memory, as well as the role of state events in the local memorial policy, e.g., the 100th anniversary of the Republic of Sakha. The author believes that historical politics contributes to the development of national identity via the culture of memory and the memorial canon. The results of the study suggest that elites became the main actor of historical policy because they shape the local memorial culture in an attempt to legitimize their own status with the help of various memory tools, including narrative practices and their visualization.
Phenomenon of Fasting in the Early Christian Anglo-Saxon Tradition
Authors: Proskurina A. V.
Published: November 2022

: The Old English poem Seasons for Fasting was written in the X century and consists of 230 lines. This article describes it through the prism of fasting in the Old English tradition. Like any other Old English Christian sermon, Seasons for Fasting focused on the moral rules of Christian life. It represented the first procedures for seasonal fasts. The author translated the poem and performed an interdisciplinary study of the phenomenon of fasting against the background of the indisputable position of faith in the Anglo-Saxon culture. The Old and New Testaments, as well as the Indo-European myths, showed the deep cultural interconnection of archaic traditions. A detailed idea of divinely revealed truth was reflected already in the earliest Christian texts where references to commandments from the Old Testament intertwined with the moral principles of the New Testament. The goal of the study was to determine the complex nature of the traditional methods used for philological analysis  of texts and the semiotic approach to texts. The view of food as sacred and profane was manifested already at the early stages of the religious consciousness development. Traditionally, fasting issues were considered as part of prayer appeals. Seasons for Fasting stressed the New Testament idea that sinners could not enter the Kingdom of God without repentance and awareness of their unrighteous life. The paper highlights the symbolism of fire, mountains, cosmos, sacrifice, submersion, burial, and the Kingdom of Heaven. The article also provides a list of variant addresses to God used in the poem: the Old English period saw a well-developed Christian tradition, which had no direct naming for the devil.
Characterization of chemical elements of calcium silicate-based cements
Authors: Patrícia Correia de Siqueira  , Ana Helena Gonçalves de Alencar  , Daniel de Almeida Decurcio  , Julio Almeida Silva  , Carlos Estrela
Published: November 2022

The aim of this study was to characterize the chemical elements and surface of the cements: Biodentine®, Bio-C Sealer®, Endosequence® BC Sealer, MTA Angelus® and Portland Cement (PC). Material and methods: The cements were manipulated according to manufacturer’s recommendations, inserted in polyethylene tubes and kept in a 95% humidity incubator for 72 hours. The analysis of the chemical elements was performed by energy dispersive X-ray spectroscopy (EDS) coupled to a low vacuum Scanning Electron Microscope (SEM). The surface analysis was performed according to the distribution pattern, shape and particle size in images obtained using Field Emission Gun SEM (SEM-FEG). Data were analyzed descriptively for EDS chemical composition spectra and qualitatively for SEM-FEG images. Results: EDS analysis showed that all evaluated cements contained calcium and silicon rich particles. MTA Angelus® presented bismuth-rich particles, while Biodentine®, Bio-C Sealer® and Endosequence® presented zirconium-rich particles, the latter having tantalum in its composition. All materials showed a uniform distribution pattern of particles on the surface. Biodentine® and Endosequence® showed similarly shaped particles. Conclusion: The cements present particles with uniform distribution pattern and similar chemical composition, differentiating the presence of bismuth or zirconium.
Extrusão apical de debris após instrumentação de canais radiculares
Authors: Maike Goulart dos Santos  , Larissa Moreira Pinto  , Fernanda Estivalet Peske  , Marília Fagury Videira Marceliano Alves  , Ezilmara Leonor Rolim de Sousa
Published: November 2022

O preparo biomecânico promove limpeza, antissepsia e modelagem dos canais radiculares, favorecendo a eliminação de bactérias e de seus produtos, tecido pulpar vivo ou degenerado, dentina e debris dentinários contaminados. Objetivo: Avaliar a quantidade de debris extruídos apicalmente, após a instrumentação endodôntica de canais mesiais de primeiros molares inferiores, utilizando quatro técnicas mecanizadas distintas. Material e métodos: Foram usados os sistemas Protaper, Wave One, Reciproc e Wave One + Pathfile. Selecionaram-se 20 raízes mesiais de molares inferiores humanos. Debris foram coletados dentro de um Eppendorf. Os debris secos foram pesados em uma balança analítica, por três vezes consecutivas. Analisaram-se os dados no programa Stata, e o teste de Bartllet’s serviu para verificar se havia diferença significativa entre os grupos. Resultados: Não houve diferença estatisticamente significante na quantidade de debris extruídos entre os grupos, mas o grupo Protaper foi o que apresentou o maior número de debris extruídos. O grupo Wave One evidenciou o segundo maior número, enquanto Wave One + Pathfile e Reciproc tiveram a mesma quantidade, contabilizando o menor montante extruído. Conclusão: Todos os sistemas de instrumentação utilizados apresentaram extrusão apical de debris. Entretanto não houve diferença estatisticamente expressiva entre os grupos analisados.