bluuebunny/crossref_metadata_2025 huggingface dataset:
Comunidades bentônicas de infralitoral em costões rochosos adjacentes ao cultivo de Bijupirás (Rachycentron canadum) na enseada do Bananal, Baía da Ilha Grande, RJ
Authors: Amaral Marcella Zicari , Azevedo Alexandre de Freitas , Pereira Marcos Bastos , Da Silva Mônica Dias Corrêa
Published: December 2022

Este estudo teve como objetivo avaliar os efeitos do cultivo de bijupirás sobre a comunidade bentônica de infralitoral por meio da caracterização de sua composição e estrutura em três estações na Enseada do Bananal, Ilha Grande, Rio de Janeiro. Foram calculadas riqueza, diversidade e equitabilidade das espécies. As diferenças entre os resultados de riqueza para comparações entre os pontos e as campanhas também foram avaliadas. Foram identificados 27 táxons entre invertebrados e macroalgas: Bryozoa (01), Cnidaria (5), Gastropoda (1), Porifera (4), Chordata (4), Chlorophyta (4), Phaeophyta (3) e Rhodophyta (5). Foi observada menor riqueza na estação do Cultivo, entretanto notou-se os maiores valores dos índices de diversidade e equitabilidade nesta mesma estação. A composição e estrutura das comunidades bentônicas do infralitoral das áreas controle e da área adjacente ao cultivo de bijupirás não distinguiram entre si, e o padrão biogeográfico está em conformidade com o de outras regiões da Baía da Ilha Grande e com a costa brasileira. Sugere-se complementação com novos estudos de médio a longo prazo, para análise de alterações decorrentes de fazendas marinhas.
Patient and healthcare staff viewpoints on EMR access and confidentiality
Authors: Muralidharan M. , Jeyachidra J.
Published: December 2022

A patient's health and well-being, as well as data from at least one healthcare interaction, are included in the EMR system. It may be accessed on a multi-level basis, with authentication according to the user type, inside an institution. The electronic medical record (EMR) system aids doctors in providing better care since it provides a comprehensive medical history for each patient. There are still many misconceptions about electronic medical records (EMR) in the minds of patients and hospital employees throughout the world, and this study aims to fill those gaps. A decade ago, searching PubMed and Google Scholar in addition to several specialized datasets like PsycINFO (Psychiatry Information Services) and Medline (Medical Library) (2007-2017).  citations to papers that referenced a certain standard were included in the quality rating process. More than 1,300 entries were considered before just 78 were left for further examination. Access to non-medical information and the opportunity to examine electronic medical data were some of the concerns voiced by patients. However, even the best in-person explanation can't compensate for control over the EMR's content and access.
Low protein intake impacts on bone mineral density
Authors: Boun Samer Mahmoud Al , Hani Khaled Mohammad Bani , Khreisat Rania Farhan , Jaradat Ra'd Qasim , Alboun Ahmed Mahmoud , Al_Quraan Kholoud Muhsen
Published: December 2022

Background/Aim: Protein may play a positive beneficial role in the augmenting Bone Mineral Density (BMD), mitigation bone resorption and consequently risk of osteoporosis. The effect of dietary protein may be different in older adults compared to younger adults, since this population has a greater need for protein. The aim of this study is to investigate the impact of a dietary protein intake below the Recommended Dietary Allowance (RDA) of 0.8 g/kg /day from any source (Group I) on Bone Mineral Density (BMD) to a higher dietary protein intake ≥0.8 g/kg/day in our Jordanian osteoporotic patients. Methods: This study trial was a single-center retrospective study, conducted for 206 participants who attended the rheumatology clinic between Sep 2021 and Nov 2021 at Prince Rashid Bin Al-Hasan Military Hospital under ethical approval of Ref #24, 1/2022. The results were expressed as Mean±SD and as Mean difference±SEM. The correlation strengths of binary categorical variables were also expressed as an odds ratio. FRAX score of 3% was used in our study to dichotomize the overall cohort into two cohorts. Univariate and Multivariate Linear Regression Tests were conducted sequentially to abstract the significant coefficients for predicting the 10-year fOHF risk.
Fitorremediación de suelos contaminados por metales pesados: una revisión
Authors: López Hernández Maybis Eugenia , Morales Hernández Osman Enrique
Published: December 2022

El presente artículo tiene como objetivo proporcionar una descripción de los conceptos básicos de la fitorremediación como una tecnología amigable y viable para la remediación de los suelos por metales pesados. Mediante la recopilación de documentación en base de datos confiables y una revisión de literatura disponible, se incluyeron publicaciones vinculados a la fitorremediación de sitios contaminados. Dentro de la fitorremediación existen diferentes estrategias como la fitoextracción, fitoestabilización y fitovolatilización, que poseen ventajas como la remoción permanentemente de los metales del suelo sin alterar la calidad del suelo, contribuye a restaurar la vegetación del sitio y reducir la erosión del suelo, además, se puede aplicar de manera in situ o e x situ. Sin embargo, entre sus desventajas se encuentra el periodo de tiempo prolongado, la fitotoxicidad de las plantas y biodisponibilidad del metal, y el tratamiento de la biomasa contaminada cuyas alternativas de manejo incluyen su deposición en vertederos para desechos peligrosos o incineración para la purificación y recuperación de los metales pesados. Otra alternativa es la utilización de la biomasa como bioenergía, no obstante, existe poco conocimiento sobre las emisiones que se podrían generar durante este proceso. Entre los desafíos de la fitorremediación se encuentran la baja tasa de crecimiento de las plantas, raíces poco profundas y poca producción de biomasa, así como las plagas y enfermedades que pueden reducir la eficiencia en la remoción de los contaminantes. La fitorremediación ha tenido un gran auge en los últimos años, sin embargo, aún hay desafíos que enfrentar para lograr una fitorremediación sostenible.
Penetapan harta asas pembayaran diat dalam konteks Malaysia
Authors: Abdul Mutalib Lukman , Wan Ismail Wan Abdul Fattah , Baharuddin Ahmad Syukran , A Rashid Radzniwan , Haji Mahat Naji Arafat , Mohd Razali Muhamad Darwisy
Published: December 2022

Islam provides a unique two-pronged legal mechanism that is known as diyya. Diyya is not just a punishment for the offender in the form of a fine but also compensation for the victim. A certain amount of fine must be paid by the offender. Unlike summons, the compensation paid belongs to the victim and is not taken by the authorities. However, in the context of the implementation of diyya, the questions that arise are: who will bear the burden of this and what property can be used as a medium of payment? Hence, this article will describe the concept of diyya property in its implementation situation in Malaysia and the types of property that can be used for diyya payment. This article will also focus on the diyya rate and methods to set the rate in Malaysia. The methodology used is a library research method based on primary sources such as hadith and secondary sources from the collection of documentation such as books, articles, journals, working papers, internet sources, newspapers, and others. This article sums up the concept of main property in a country. In the context of Malaysia, it is the national currency which is the Malaysian Ringgit (RM). The ratio of the exchange of Dirham to RM transactions is applicable in Malaysia.
Erythropoietin Reduces Death and Neurodevelopmental Impairment in Neonatal Hypoxic-Ischemic Encephalopathy
Authors: Bang Seung Jun , Lee Juyoung , Jeon Ga Won , Jun Yong Hoon
Published: December 2022

Purpose: Erythropoietin (EPO) is a promising neuroprotective drug. We investigated whether EPO has beneficial effects on neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy (HIE).Methods: We retrospectively reviewed the data of 56 infants with HIE born at or after 35 weeks of gestation who were admitted to Inha University Hospital between 2012 and 2021. Patients were divided into two groups based on EPO use and compared. In the EPO group, patients were administered 1,000 U/kg of EPO on days 1, 2, 3, 5, and 7, starting within 24 hours after birth. The primary outcome was death or neurodevelopmental impairment (NDI) at the age of 12 months.Results: EPO was administered to 38 infants, and 18 did not receive EPO. Only 37.5% of patients with HIE (21/56) and 60% of patients with moderate-to-severe HIE (21/35) received therapeutic hypothermia. Among all patients with HIE, death or NDI (21.1 % vs. 50.0%; odds ratio [OR], 0.09; 95% confidence interval [CI], 0.01 to 0.78; P=0.029) and brain injury on imaging (42.1% vs. 83.3%; OR, 0.16; 95% CI, 0.03 to 0.92; P=0.040) were significantly lower in the EPO group than in the control group. Among patients with moderate-to-severe HIE, brain injury on imaging (54.2% vs. 90.9%; OR, 0.04; 95% CI, 0.002 to 0.700; P=0.027) was significantly lower in the EPO group than in the control group.Conclusion: EPO administration significantly reduced mortality and NDI in infants with HIE. EPO can be considered an adjunctive therapeutic agent for neonatal HIE.
Rapidly Progressive Pericardial Effusion and Cardiac Tamponade in a Term Infant with an Umbilical Venous Catheter: A Case Report
Authors: Park Min-Jung , Ahn Ja-Hye , Lee Hyun Ju , Park Hyun-Kyung , Hwang Jae-Kyoon , Kim Chang-Ryul , Na Jae Yoon
Published: December 2022

Pericardial effusion (PCE) in neonates has various clinical presentations depending on the amount and speed of fluid accumulation and can cause cardiac tamponade (CT). We report a case of rapidly accumulating PCE and near-fatal CT with an umbilical venous catheter successfully resolved by emergent echo-guided pericardiocentesis in a term infant who had been hospitalized with meconium aspiration syndrome and persistent pulmonary hypertension. This case report suggests that if a patient with an intracardiac umbilical catheter shows sudden cardiopulmonary instability, the possibility of PCE and CT should be considered. Furthermore, if necessary, emergency drainage of the PCE and removal of the umbilical catheter should be immediately performed.
Newborn Periventricular Nodular Heterotopia with Persistent Feeding Cyanosis and Apneic Spell: A Case Report
Authors: Hong Seok Jin , Park Ji Eun , Sohn Young Bae , Suh Yoong A , Lee Jang Hoon , Park Moon Sung
Published: December 2022

Periventricular nodular heterotopia (PNH) is a neuronal migration disorder that occurs during early brain development. Patients with PNH may be asymptomatic and have normal intelligence; however, PNH is also known to cause various symptoms such as seizures, dyslexia, and cardiovascular anomalies. PNH is not commonly diagnosed during early infancy because of the lack of clinical manifestations during this period. We present the case of a female infant diagnosed with PNH based on brain magnetic resonance imaging, who had symptomatic patent ductus arteriosus that had to be ligated surgically and had prolonged feeding cyanosis with frequent apneic spells.
Hipofisitis con imagen normal
Authors: González-Arango Juanita , García Andrés Felipe , Estupiñán-Vargas Valentina , Monsalve-Arango Claudia , Aguilar-Londoño Carolina , Aristizabal-Henao Natalia , Torres-Grajales José Luis
Published: December 2022

Introducción: la hipofisitis es una enfermedad inflamatoria de la hipófisis que puede comprometer cualquier porción de la glándula y generar alteración en los ejes hormonales. Dentro de las causas primarias la más frecuente es la hipofisitis linfocítica o autoinmune.
Objetivo: presentar un caso de interés con el abordaje clínico realizado.
Presentación del caso: en el texto se presenta el caso de una paciente con antecedente personal de lupus a quien se le documentan deficiencias hormonales hipofisiarias y en quien se realiza un diagnóstico presuntivo de hipofisitis autoinmune con base en la clínica y los hallazgos de laboratorios, pero con imágenes craneales normales, descartando los demás diagnósticos diferenciales.
Discusión y conclusión: la hipofisitis se puede clasificar como primaria o secundaria según la causa, el diagnóstico definitivo es con la patología que en muchos casos no es necesaria. Las imágenes de silla turca apoyan el diagnóstico y ayudan a descartar diferenciales, pero existen casos descritos de hipofisitis con exámenes normales. Además, se presenta el abordaje diagnóstico a la deficiencia de hormonas pituitarias en una paciente con enfermedad autoinmune con sospecha de adenohipofisitis por clínica, antecedentes y perfil bioquímico aun en el contexto de imágenes normales.
A SYSTEMATIC OVERVIEW ON NOSE TO BRAIN DRUG DELIVERY SYSTEM IN TREATMENT OF NEURODEGENERATIVE DISORDERS
Authors:   Department of Pharmaceutics, D. Y. Patil Institute of Pharmaceutical Education and Research, Pimpri, Pune - 411 018, Maharashtra, India, R. Pagar Roshani , V. Suryawanshi Meghraj
Published: December 2022

Improving the treatment of neurodegenerative disorders such as Parkinson’s (PD) and Alzheimer’s disease (AD) has always been challenging. Compared with oral drug administration, nasal mucosa has emerged as a convenient target tissue for drug delivery because of its accessibility, high blood perfusion, greater surface area, permeability and ability to escape the first-pass metabolism. The BBB is the least reachable portion of the human body to active pharmacological molecules. While useful in the treatment of neurodegenerative disorders, conventional approaches fail to achieve maximum effectiveness. Hence, there is a need to invent therapeutic alternatives. This review comprises a brief explanation of the currently developed nose-to-brain drug delivery systems in treating neurodegenerative disorders. It further contrasts the strengths, disadvantages, and future viewpoints from which innovative drug research and therapy can be based.
NOVEL STABILITY INDICATING RP-HPLC METHOD FOR ESTIMATION OF CLOBAZAM AND ITS RELATED SUBSTANCES IN ORAL SUSPENSION
Authors:   Department of Pharmaceutical Chemistry, PES Modern College of Pharmacy (For Ladies), Moshi, Pune-412 105, Maharashtra, India, M. Tathe Reshma , S. Tambe Vrushali , M. Karnik Archana , U. Nalwade Santaji
Published: December 2022

A novel, sensitive, stability-indicating gradient RP-HPLC method has been developed for simultaneous estimation of clobazam and its related substances in oral suspension. The chromatographic separation of degradation products and matrix components was executed on a YMC Pack ODS-A column with gradient mode. The mobile phase composed of water and acetonitrile and flow rate was 1.0 mL min-1, while 230 nm was wavelength of detection. The resolution greater than 2.0 between clobazam and the impurities was achieved. The forced degradation study was carried out as per ICH guidelines. The drug product was exposed to hydrolysis, oxidation, photolysis and thermal conditions to achieve degradant formation. Clobazam was degraded under acidic and basic hydrolytic conditions that produced impurity E. The specificity, linearity, limit of detection/quantification, accuracy, precision and robustness was validated as per ICH guidelines.
STABILITY INDICATING RP-HPLC PDA ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF BESIFLOXACIN HYDROCHLORIDE IN BULK AND FORMULATION
Authors:   Department of Pharmaceutical Chemistry, Dr. D.Y. Patil Institute of Pharmaceutical Sciences & Research, Pimpri, Pune - 411 018, Maharashtra, India, G. Chate Subhash , S. Birajdar Arunadevi
Published: December 2022

The goal of the study was to provide an overview of the technique development and validation of a stability-indicating HPLC approach for routine analysis of besifloxacin hydrochloride in pharmaceutical product (ophthalmic suspension). HPLC method was development on octadecasilyl silica (C18, 250 mm x 4.6 mm x 5µ) column at 37 °C and isocratic mode with a running solvent (phosphate buffer: methyl alcohol 40:60 % V/V) using flow rate (1.0 mL minute-1) and UV wavelength 292 nm. Proposed method was validated for specificity, linearity, accuracy, precision, range and robustness according to ICH Q2 (R1) standards. The collected results attest to the validated method’s compliance with the set acceptance standards. Besifloxacin hydrochloride was subjected to hydrolytic, oxidative, thermal and photolytic stress conditions. These samples were then examined using our suggested approach. Hence, this method can be used for routine use for determination assay of besifloxacin hydrochloride drug substance (API) and drug product (ophthalmic suspension).
MOLECULAR DOCKING STUDY OF COMPOUND ISOLATED FROM COCCINIA GRANDIS (L.) VOIGT
Authors:   Department of Pharmaceutical Chemistry, Annasaheb Dange College of B. Pharmacy, Ashta, Sangli- 416 301, Maharashtra, India, H. Momin Yasmin , C. Yeligar Veerendra
Published: December 2022

Compound (9Z, 12Z)-octadeca-9, 12-dienoic acid (CGHY 02) was isolated from Coccinia grandis (L.) Voigt n-butanol extract by column chromatography. A molecular docking study against human pancreatic alpha-amylase enzyme (PDB: 3OLE) yielded a good docking score of -112.37 Kcal mol-1, indicating a high affinity of the compound to the receptor via hydrogen bonds, electrostatic interactions and hydrophobic interactions. The hydrogen bond was observed between the hydroxyl group of the compound and glutamine 8, whereas the carbonyl group and C5-C9 chain of the compound revealed steric interactions with glutamine 8 and aspartate 402, respectively. In vitro alpha-amylase inhibition of (CGHY 02) demonstrated remarkable inhibition (68.47 %) at low concentration (100 µL mL-1) compared to standard acarbose. Moreover, in silico ADME analysis of the compound exhibited 92.282 % gastrointestinal absorption, skin permeability, activity as a substrate for CYP2D6 and CYP3A4 enzymes resulting in better metabolism and 1.936 (logn ml min-1 kg-1) of total clearance of the compound. In silico toxicity predicted carcinogenicity, mutagenicity via PreADMET online server and hepatotoxicity and skin irritations via pkCSM online platforms. Antidiabetic potential of (CGHY 02) is attributed through inhibition of human pancreatic alpha amylase enzyme.
IN VITRO EVALUATION OF THE ANTIOXIDANT PROPERTY AND DPPH RADICAL SCAVENGING KINETIC BEHAVIOR OF ALGERIAN QUERCUS ROBUR L. LEAVES’ SELECTIVE EXTRACTS
Authors:   Department of Biology, Mohammed Tahri University of Bechar, Bechar - 08000, Algeria, Benyagoub Elhassan , Nabbou Nouria , K. Alkhudhairy Miaad , Dine Amal
Published: December 2022

Today, there is a growing demand for natural antioxidants. The unbalanced production and consumption of reactive oxygen species cause many disorders such as cancer, arteriosclerosis, Alzheimer’s disease and aging. For this purpose, the present study was a part of the in vitro evaluation of the antioxidant activity of Quercus robur L. leaves’ selective extracts, namely tannins and saponins groups. The antioxidant activity was evaluated by using two techniques: the DPPH radical scavenging activity method and the ferric reducing antioxidant power method. In addition, a kinetic behavior study of the antiradical activity was established. The obtained results show that tannins and saponins extracts have a significant free radical scavenging activity with IC50 values of 0.128 and 0.145 mg mL-1, respectively. Moreover, the kinetic behavior of the scavenging ability of the studied extracts makes it possible to determine the antiradical efficiency, the antiradical power, the percentage of the remaining DPPH free radical, the TIC50 parameter, the half-reaction time and the equilibrium antiradical reaction time. These results showed that the tested extracts provided a significant antioxidant activity. This plant can keep an important value in pharmacy and herbal medicine, and act as natural agents in food applications.
AMELIORATIVE EFFECT OF ETHANOLIC EXTRACT OF COPTIS TEETA WALL. ROOTS IN ALLOXAN INDUCED DIABETIC RATS
Authors:   Department of Pharmacology, Ramanbhai Patel College of Pharmacy, CHARUSAT Campus, Changa - 388 421, Gujarat, India, P. Shah Bhagyabhumi , R. Patel Dipen , K. Shah Samir
Published: December 2022

The antidiabetic activity of Coptis teeta extract (CE) was investigated in a diabetic rat model. Alloxan (150 mg kg-1, i.p.) was used to induce hyperglycemia in rats. Oral administration of CE at the dose of 250 and 500 mg kg-1 for 28 days lowered the blood glucose level. Various physical parameters (body weight, food and fluid intake) and biochemical parameters like serum glucose, insulin level and kidney functions were measured. Results revealed that rats treated with CE forbade the decrease in body weight, and showed a significant (p<0.05) reduction in food and fluid intake, serum glucose, serum urea, serum creatinine, and a significant increase in insulin level and serum protein as compared to diabetic rats. Histopathological study of kidneys supported the data and CE reduced the damage to the glomerulus and bowman capsule produced by alloxan. The study clearly shows that the ethanolic extract of C. teeta possesses potent antidiabetic activity
Causes and Solutions for Iron and Zinc Deficiencies among Vietnamese Children
Authors: Nguyen-Hoang Anh
Published: December 2022

The prevalence of zinc deficiency in Vietnam is high in children. It was often associated with iron deficiency. Deficiencies of zinc and iron have been widely recognized as a public health issue in Vietnam. Zinc and iron are important trace elements in the body, particularly in developing children’s body. The deficiency of these micronutrients without correction is related to cognitive impairment and immune dysfunctions in children. Moreover, evidence shows that an inadequate intake of zinc and iron could cause growth retardation due to an impairment of growth hormones and related other factors. The review has revealed factors contributing to the deficiencies of these micronutrients in this population. Combined zinc-iron supplementations and food fortifications have been recognized as possible strategies to solve this issue, but further studies need.
Asal-Usul Kejahatan dan Penderitaan Menurut Kitab Kejadian 3:1-24 dan Usaha Manusia Melawan Dosa
Authors: Adon Mathias
Published: December 2022

The story of the fall of man is told dramatically in Genesis 3: 1-24. This story illustrates how humans abuse their freedom as rational beings who are called to love God and others. Human disloyalty to this calling causes humans to be expelled from Eden. The fall into sin not only makes humans lose guarantees and protection but also brings suffering. In this situation, Satan uses the state of sin to tempt people to do evil. Therefore, this research aims to find the origins of evil and human efforts to get out of the shackles of sin. Because the fall of humans into sin is caused by humans listening more to the tempter (satan) than God. This study uses the method of literature study. This research finds that God is not the cause of human suffering but rather the human rejection of God's love. So, to obtain happiness, humans must get out of the shackles of sin by using free will to fight the temptations of the evil one.

Kisah kejatuhan manusia dikisahkan secara dramatis dalam Kejadian 3: 1-24. Kisah ini melukiskan bagaimana manusia menyalahgunakan kebebasannya sebagai makhluk yang berakal budi yang dipanggil untuk mencintai Allah dan sesama. Ketidaksetiaan manusia terhadap panggilan ini membuat manusia diusir dari Eden. Kejatuhan dalam dosa tidak hanya membuat manusia kehilangan jaminan dan perlindungan tetapi juga mendatangkan penderitaan. Dalam situasi ini, setan menggunakan keadaan dosa untuk menggoda manusia untuk melakukan kejahatan. Karena itu, penelitian ini bertujuan menemukan asal-usul kejahatan dan upaya manusia untuk keluar dari belenggu dosa. Sebab kejatuhan manusia dalam dosa disebabkan karena manusia lebih mendengarkan si penggoda (setan) dari pada Allah. Penelitian ini menggunakan metode studi kepustakaan. Penelitian ini menemukan bahwa Allah bukanlah penyebab penderitaan manusia melainkan penolakan manusia terhadap kasih Allah. Maka, untuk memperoleh kebahagiaan, manusia harus keluar dari belenggu dosa dengan menggunakan kehendak bebas untuk melawan godaan si jahat.
Multiple attribute decision making for square root diophantine neutrosophic interval-valued sets and their aggregated operators
Authors:   Department of Mathematics, Saveetha School of Engineering, Saveetha University, Saveetha Institute of Medical and Technical Sciences, Chennai-602105, India, Palanikumar M. , Broumi Said ,   Laboratory of Information Processing, Faculty of Science Ben MSik, University of Hassan II, Casablanca, Morocco;Regional Center for the Professions of Education and Training (C.R.M.E.F), Casablanca-Settat, Morocco
Published: December 2022

Square root Diophantine neutrosophic interval-valued set (SRDioNIVS) approaches to multiple attribute decisionmaking (MADM) problems. The square root neutrosophic sets, interval-valued Diophantine neutrosophic sets are both extensions of square root Diophantine neutrosophic sets. In this section, we discuss aggregating operations and how those interprtautions have evolved over time. The paper is focused on a novel idea known as square root neutrosophic interval-valued weighted averaging (SRDioNIVWA), square root neutrosophic interval-valued weighted geometric (SRDioNIVWG), generalized square root neutrosophic interval-valued weighted averaging (GSRDioNIVWA), and generalized square root neutrosophic interval-valued weighted geometric (GSRDioNIVWG). We also begin an algorithm using these operators. The use of the euclidean and hamming distances is described, and examples from real-world problems are inserted. As a result, the defined models are more accurate and closely tied to Ξ. In order to show the reliability and usefulness of the models under examination, we also compare a few of the proposed and current models. The study’s results are also fascinating and intriguing.
Large-Scale Screening of the Plant Extracts for Antifungal Activity against the Plant Pathogenic Fungi
Authors: Lee Song Hee , Oh Young Taek , Lee Do-Yeon , Cho Eunbyeol , Hwang Byung Su , Jeon Junhyun
Published: December 2022

Plants produce chemicals of immense diversity that provide great opportunities for development of new antifungal compounds. In search for environment-friendly alternatives to the fungicide of current use, we screened plant extracts obtained from more than eight hundred plant materials collected in Korea for their antifungal activity against the model plant pathogenic fungus, Magnaporthe oryzae. This initial screening identified antifungal activities from the eleven plant extract samples, among which nine showed reproducibility in the follow-up screening. These nine samples were able to suppress not only M. oryzae but also other fungal pathogens. Interestingly, the plant extracts obtained from Actinostemma lobatum comprised five out of eight samples, and were the most effective in their antifungal activity. We found that butanol fraction of the A. lobatum extract is the most potent. Identification and characterization of antifungal substances in the A. lobatum extracts would provide the promising lead compounds for new fungicide.
Xylella fastidiosa in Europe: From the Introduction to the Current Status
Authors: Trkulja Vojislav , Tomić Andrija , Iličić Renata , Nožinić Miloš , Milovanović Tatjana Popović
Published: December 2022

Xylella fastidiosa is xylem-limited bacterium capable of infecting a wide range of host plants, resulting in Pierce's disease in grapevine, citrus variegated chlorosis, olive quick decline syndrome, peach phony disease, plum leaf scald, alfalfa dwarf, margin necrosis and leaf scorch affecting oleander, coffee, almond, pecan, mulberry, red maple, oak, and other types of cultivated and ornamental plants and forest trees. In the European Union, X. fastidiosa is listed as a quarantine organism. Since its first outbreak in the Apulia region of southern Italy in 2013 where it caused devastating disease on Olea europaea (called olive leaf scorch and quick decline), X. fastidiosa continued to spread and successfully established in some European countries (Corsica and PACA in France, Balearic Islands, Madrid and Comunitat Valenciana in Spain, and Porto in Portugal). The most recent data for Europe indicates that X. fastidiosa is present on 174 hosts, 25 of which were newly identified in 2021 (with further five hosts discovered in other parts of the world in the same year). From the six reported subspecies of X. fastidiosa worldwide, four have been recorded in European countries (fastidiosa, multiplex, pauca, and sandyi). Currently confirmed X. fastidiosa vector species are Philaenus spumarius, Neophilaenus campestris, and Philaenus italosignus, whereby only P. spumarius (which has been identified as the key vector in Apulia, Italy) is also present in Americas. X. fastidiosa control is currently based on pathogen-free propagation plant material, eradication, territory demarcation, and vector control, as well as use of resistant plant cultivars and bactericidal treatments.
تعميم وايبول للتوزيع الأسي
Authors: الجراش د. شمسان عبد الله ناصر
Published: December 2022

تقدم هذه الورقة البحثية تعميم جديد للتوزيع الأسي، وهو عبارة عن نموذج أو موديل يحتوي على ثلاثة بارامترات، يسمى تعميم وايبول للتوزيع الأسي، والذي له دالة نسبة المخاطر على حياة أوبقاء أي نظام على شكل bathtub-shaped ، تم إيجاد بعض الخصائص الإحصائية للنموذج الجديد، مثل: مقاييس الموضع، والعزوم، والدالة المولدة لها، ودالة الموثوقية، والاحصاء المرتب. كما تم تقدير بارامترات النموذج باستخدام طريقة الاحتمال الأعظم ومشتقة مصفوفة فيشر. وأخيراً تم توضيح أهمية التعميم الجديد وكفاءته، من خلال تطبيق لبيانات حقيقية، ومقارنة مع تعميمات أخرى للتوزيع الأسي.
APLIKASI PENDAFTARAN SISWA BARU SEBAGAI SISTEM INFORMASI MANAJEMAN BUKU INDUK SISWA SMK AL QOLAM KOTAAGUNG
Authors: Irviani Rita , Nungsiyati Nungsiyati , Widodo Bagus
Published: December 2022

Admission of new students is a process found in educational institutions in public or private schools. The process of accepting new students is the beginning of the administrative management of student profiles in schools. In an effort to improve the school administration of SMK Al-Qolam Kotaagung, Tanggamus Regency, trying to use Mobile technology as an effort to improve administration and electronic archives by implementing new Student Admissions with Mobile Web. The research method uses the waterfall stage in application development, in collecting data using the interviews, interviews, and library studies. The result of this research is the creation of a Mobile-based Al-Qolam Kotaagung Vocational New Student Admission application that helps prospective students in online registration with the Mobile application. With this application, prospective new students can fill out the registration form for the registration of new students so that it will be easier to recap the data of prospective students, as well as improve data accuracy. The recorded data will be a reference for re-registration and will then become the main book data for each student, thus providing convenience in the administration of Administrative Management and Academic Management at SMK Al-Qolam Kotaagung.
SISTEM PENDUKUNG KEPUTUSAN PENILAIAN KINERJA GURU BERPERESTASI MTS YPPTQMH AMBARAWA DENGAN METODE SIMPLE ADDICTIVE WEIGHTING
Authors: Ulfa Zuhria , Kasmi Kasmi
Published: December 2022

Teacher performance evaluation in a school is an activity to evaluate the performance of every teacher in the school. MTS YPPTQMH Ambarawa is one of the schools where the performance appraisal process for each teacher is carried out once a year, which coincides with National Teacher's Day. The assessment process carried out includes teacher assessment by students, teacher discipline in giving material to students, allocation of teaching time, last education and academic position. Using the Simple Addictive Weighting method can assist in making decisions to determine teacher performance assessments, as well as more efficient teacher assessments so that schools get information about teacher performance more quickly. By using a decision support system that has a database, data from teacher performance assessments can be stored in the database. So that if there is an error in inputting value-taking data, then the data that has an error can be corrected without having to re-enter it.
Language: Charioteer of culture and development
Authors: Wadekar Dr Jayshree Bhaskar
Published: December 2022

Giving a complete definition of culture is a very difficult task. There is a saying in English that civilization is what we have, culture is what we have, in other words, culture is related to the soul, whatever is helpful in the progress of the soul, is the tool of all culture. Music and various arts are the tools of all culture, the culture of the interest of the mind. The means and tools by which all of them come in the field of culture. Civilization Where there is intellectual development, culture is where there is mental development. Man will become human only by having mental development. Man is the only such species in the world. By itself, human values are greater than ourselves, and are always committed to protect them. Culture is concerned with the human-made mental environment. Culture is the expression of our intrinsic nature in our way of living and thinking. Two divisions of culture can be said. physical and non-material. Material culture is related to the subjects that we call our civilization, and are related to the physical aspects of our life, such as our clothes, food, household items etc. Non-material culture is related to ideas, ideals, feelings and beliefs. The people of any country are identified only by their specific cultural traditions.
Nivel de comprensión de la lectura en los estudiantes del sexto grado de educación primaria de la institución educativa, Perú
Authors: Apacclla Alfonzo Nataly Ibeth , Huaman Huamaní Ronald Esteban
Published: December 2022

Este trabajo se ha realizado con la finalidad de conocer el nivel de comprensión de la lectura en los estudiantes del sexto grado de educación primaria; la metodología de la investigación es básica, con nivel descriptivo; en este contexto se ha utilizado un instrumento que contiene 20 preguntas de corte dicotómico que los estudiantes han dado respuesta luego de haber leído un texto que contiene una fábula. Dicho instrumento que es el test de comprensión de la lectura se ha administrado en un tiempo de 45 minutos aproximadamente a un grupo de 19 estudiantes de ambos sexos. Una vez obtenida la información se ha realizado el procesamiento de la información de los datos obtenidos. Los resultados muestran que, en el nivel literal 89.5% alcanzan el nivel promedio; solo el 10,5% se ubica en el nivel alto y ninguno se ubica en el nivel bajo. En el nivel inferencial se obtuvo un 94.7% ubicándose en el nivel promedio; solo el 5.3% se ubica en el nivel bajo y ninguno se ubica en el nivel alto. El nivel crítico un 47.4% corresponde al nivel bajo y un 52.6% en el nivel promedio; ninguno se ubica en el nivel alto. En tal sentido, se deduce que los estudiantes del 6to grado en el proceso de la comprensión de la lectura se ubican en un término promedio.
Makó és környéke halmainak kataszterezése, állapotfelmérése és tájrégészeti vizsgálata
Authors: Bede Ádám
Published: December 2022

Makó és környéke tizenkilenc településén, összesen 781,82 km2 kiterjedésű területen végeztük el a halmok (kurgánok) teljességre törekvő kataszterezését és állapotfelmérését. A 18–20. századi kéziratos és későbbi nyomtatott térképeken kívül felhasználtuk a levéltári forrásokat, adattári jelentéseket, helytörténeti, régészeti, néprajzi, névtani és természettudományos irodalmat is. A tájrégészeti szemléletű kutatás során a régészeti topográfiai módszertan alkalmazása mellett tájtörténeti és tájökológiai eredményeket is felhasználtunk. A 20. századi halomkataszterek beszámolóit elemezve arra következtetünk, hogy a korábbi felmérések nem aknázták ki a források, elsősorban pedig a kéziratos térképek adta lelőhely-azonosítási lehetőségeket, ezért lehet esetenként többszörös eltérés az egyes felmérések halomszámai között. Összesen 218 halmot regisztráltunk. A Tiszántúl más részeihez hasonlóan a vizsgálati területen is elsősorban a hidrogeográfiai viszonyok határozzák meg a kurgánok földrajzi helyzetét (folyók, erek, meanderek partjait, homokvonulatok gerincét követik). A felmérés során egy hétfokú skálát dolgoztunk ki a halmok rangsorolása céljából, hogy a legjelentősebbeknél minél előbb megindulhassanak a konkrét védelmi intézkedések. A jelentős halmok az 1-es, 2-es és 3-as, a nem jelentősek a 4-es és 5-ös, a már elpusztítottak pedig a 6-os és 7-es kategóriába kerültek. A jelentős halmok (1–3. kategória) száma összesen 53 (24,3%), a nem jelentőseké (4–5. kategória) 91 (41,8%), elpusztítottnak tekinthető (6–7. kategória) 74 halom (ez 33,9%-ot tesz ki). A halomnevek elemzése módot ad a hajdani környezet (földrajzi viszonyok, állat- és növényvilág), a mezőgazdaság (állattenyésztés, növénytermesztés) és a birtoklástörténet (birtokosok, határviszonyok) megértéséhez is. A regisztrált kurgánok közül 96 rendelkezik névvel (44%), 122 pedig névtelen (56%). További vizsgálati lehetőséget kínál a halmokhoz kapcsolódó folklórgyűjtések elemzése. A gyakorlati védelem egyre sürgetőbb feladat, hiszen a nagysúlyú mezőgazdasági munkagépek a legalacsonyabb s egyben a legnagyobb számban lévő halmokat belátható időn belül el fogják pusztítani, ezért ezeket minél előbb ki kell venni a szántóföldi művelés alól. A magyarországi halmok egy része védett tájképi elemként bekerült az Európai Unió Közös Agrárpolitikája (KAP) által előírt Helyes Mezőgazdasági és Környezeti Állapot (HMKÁ) hazai feltételrendszerébe, ami örvendetes előrelépés a gyakorlati megóvás terén.
Archaeometric Investigation of the Kunágota-Sword : A Case Study
Authors: Török Béla , Barkóczy Péter , Langó Péter , Tóth Boglárka
Published: December 2022

Among the Early Medieval double-edged swords, excavated in the Carpathian Basin, there are a few which probably have Byzantine origin. The most unique piece of this small but significant group of weapons was unearthed at Kunágota, Southern Hungary. The sword, which has a special sword-guard made of bronze, has been examined by the experts of the Archaeometallurgical Research Group of the University of Miskolc with optical microscopy, SEM-EDS, ED-XRF, and microhardness tests. The primary aim was to study the microstructure of the blade and guard. There was also an important objective of the investigations to explore the possible manufacturing technology. Due to the metallographic examination, it was possible to reconstruct the manufacturing process of the Kunágota-sword. Three samples were taken from the sword for metallographic examination, two of them (K1A and K1B) were collected from the sword-guard and one (K2) from the blade. To summarise the results, it can be established that the basic material of the Kunágota-sword guard is a heterogeneous copper-alloy with high lead content. In the core area of the blade sample a very fine pearlitic structure can be seen. Towards the edge of the blade, a martensitic microstructure can be observed which probably proves a kind of heat treatment of the sword. With the aid of archaeometric investigations, our knowledge related to Byzantine swords can be deepened. Further interesting results can be gained by comparing with the characteristics of other Byzantine swords found of the Carpathian Basin.
Hajdúnánás-Zagolya ETA-01 kurgán (Hajdú-Bihar Megye) régészeti talajtani és geokémiai adatokra alapozott rétegtani vizsgálata
Authors: Braun Ádám , Dani János , Kulcsár Gabriella , Milinkó István , Kovács Gabriella , Heyd Volker , Pető Ákos
Published: December 2022

A kurgánok kiemelkedő fontosságú tájelemei a közép-kelet-európai síkságoknak mind ökológiai, talajtani és régészeti szempontból, így a hazai geoarcheológiai kutatások fontos alanyai. A régmúltban emelt síremlékek időkapszulaként információt őriznek az építőikről és környezetükről. A kézzel fogható tárgyi emlékeken túl az építés során eltemetődött talaj és maga a halomtest is információkkal szolgálhat, ha megvizsgáljuk talajtani és geokémiai sajátosságait. A Hajdúnánás–Zagolya dűlőben feltárt ETA-01 gödörsíros (Jamnaja) temetkezési halomból összesen 39 elem került vizsgálatra. A talajminták királyvízzel oldható frakcióját vizsgáltuk ICP-MS és MP-AES módszerekkel. Az elemkoncentrációk sokváltozós statisztikai módszerekkel történő kiértékelésével feltártuk a talajtani módszerrel kialakított szintek, rétegek és a talaj kémiai összetétele közötti kapcsolatot. A csoportok közötti különbségekből pedig azok eredeteire kerestünk választ. A geokémiai eredmények alapján kialakult csoportosulások jól megfeleltethetőek a talajtan módszerével megállapítható szinteknek. A geoarcheológiai vizsgálat során nyert adatok segítségével az egyes csoportok közti különbségek értelmezése vált lehetővé. A klaszterek közötti különbség megmutatta genetikai kapcsolatukat, és rávilágított a rétegek eredetére. A korabeli Zagolya-dűlő talajtani viszonyairól árulkodik a halom alatt eltemetett talajtakaró. Egy csernozjom talajfejlődéssel jellemezhető talajba mélyítették a halom központjában megtalált alaptemetkezést. Az eltemetett talaj felszínére egy szürkés sárga anyagból emeltek magasítást, amelyet nem a környezet humuszos termőrétegéből hordtak meg. A temetkezési hely tágabb tájföldrajzi környezetében előforduló alapkőzetből származhatott ez az anyag, amelynek gyűjtési helye a Zagolya-dűlőben futó vízfolyások természetes feltáródási pontjai lehettek.
Petroarcheológiai tanfolyam a szilicit nyersanyagokról – elméleti és gyakorlati képzés a Schelde és a Rajna közötti terület kőzetein
Authors: Szilágyi Kata
Published: December 2022

A cikk célja, hogy bemutassa a 2022. február 7. és 11. között Kölnben tartott petroarcheológiai képzés tapasztalatait és új ismeretanyagát. Úgy vélem ez a kiváló példa támogatja és elősegíti a hazai kőeszközkutatásban hasonló jellegű tanfolyam megszervezését. Hiszen Magyarországon is számos lelkes és elhivatott kutató járja a terepet az egykori potenciális megmunkálható kőnyersanyagok után kutatva. A Kölnben bemutatott, jól felépített petroarcheológiai kutatás elméleti és gyakorlati keretei remélhetőleg egy friss és új impulzust jelentenek a hazai szakembereknek is, hiszen területtől és nyelvtől függetlenül alkalmazhatók. Emellett a cikk egy bővebb irodalomjegyzéket tartalmaz annak érdekében, hogy a szilicitek és az evolúciós lánc elmélet publikációiról nyújtson keresztmetszetet.
A INFLUÊNCIA DA INOVAÇÃO, RISCO E SEGURANÇA NA SATISFAÇÃO DOS USUÁRIOS DOS SERVIÇOS BANCÁRIOS DIGITAIS DA REGIÃO TOCANTINA
Authors: Pereira da Silva Leão Airton
Published: December 2022

As mudanças no cenário econômico, social e tecnológico devido à pandemia do covid-19 mudaram o comportamento das empresas no que diz respeito ao relacionamento com os clientes. No setor bancário não diferiu, os bancos tiveram que se adaptar para atender as novas demandas do mercado. Além das barreiras sanitárias impostas no enfrentamento ao vírus da covid-19, tal motivo se dá pela mudança estrutural que ocorreu nos modelos empresariais bancários, fazendo assim, emergi a inovação bancária. Este trabalho pretende identificar a influência da inovação, risco e segurança na satisfação dos usuários dos serviços bancários digitais na Região Tocantina. Para tal, realizou-se uma pesquisa quantitativa descritiva e de corte transversal. Os dados foram coletados através de um questionário através da ferramenta google forms com alcance de 158 respondentes. Em relação à análise dos dados, utilizou-se a Modelagem de Equações Estruturais. A pesquisa revelou que a satisfação dos clientes que utilizam os canais digitais bancários na Região Tocantina é influenciada pela inovação e segurança. A percepção de risco influência negativamente na adoção desses canais digitais, o que denota que os bancos precisam investir mais em inovação para assegurar e minimizar os riscos envolvidos nas transações realizadas por meio digital.
RISK PERCEPTION OF UNDERGRADUATE STUDENTS IN DLSU-D AND THEIR WILLINGNESS TO TRAVEL TO MINDANAO
Authors: LEONARDO JOZAM SABADO , BALASABAS ANNE MARIE MANAHAN , DE SMET KIMBERLY CHARLOTTE LABINE , ESPLANADA DEOGRACIAS EVANGELISTA
Published: December 2022

Since the 9/11 terrorist attack, risk perception has been one of the points of study in the context of tourism. The infamous day or occurrence, which led to a significant decline in travel demand, demonstrated the critical relevance of risk research in tourism. Previous research indicates that risk perception considerably influences travel behavior, particularly when considering terror-infested areas. However, the relationship between tourist risk perceptions and willingness to travel remains fragmented due to the variable nature of their association, as indicated by a few studies, which simultaneously revealed multiple dimensions of risk perception. The present study focuses on the five dimensions of perceived risks, namely Physical Risk, Financial Risk, Socio-Psychological Risk, Performance Risk, and Time Risk, and their relationship with the tourists’ willingness to travel. The purpose of this study is to determine whether risk perception affects undergraduate students at De La Salle University-Dasmariñas' willingness to travel to Mindanao. This quantitative study utilized a purposive sampling method to gather respondents. Their risk perceptions were measured using a questionnaire that experts validated. The results were analyzed using Spearman's Correlation, which indicated that all perceived risk dimensions, apart from time risk, had a negative and significant relationship to the willingness to travel to Mindanao of undergraduate students at De La Salle University-Dasmariñas.
THE QUESTION OF MORAL VALUES AND DISCIPLINE FOR HIGH AND MIDDLE SCHOOL MOROCCAN STUDENTS
Authors: ISMAIL MAKAOUI
Published: December 2022

Even though all the previous ministerial documents have stressed the importance of integrating values in school, there are still myriad obstacles. Numerous studies have alerted that the Moroccan school is experiencing an intense moral crisis. Thus, this paper was an attempt to tackle the centrality of moral values in education and its intrinsic role in promoting discipline among high and middle school students. Specifically, it investigated the reasons behind the deterioration of student's morals in the last few years. This paper seeks to answer two important questions concerning the prominent manifestations of the disintegration of the value system within the school environment and the basic causes of this phenomenon. To test the hypothesis that student's decreasing discipline recently inside schools is attributed to media influence through its daily outlets on teenagers and the lack of a real and effective curriculum that focuses on teaching moral values, an online survey was distributed to 200 middle and high school teachers across Morocco. The survey analysis showed an agreement with the previous hypothesis, and the respondents added more causes that result in the degrading level of moral values among students. Finally, it was concluded that the moral values crisis in the school perimeter has accelerated in the last few years due to different reasons, mainly social, educational, and others concerned with the curriculum. The phenomenon needs to be taken into account by all the intervening parties, especially with the rising spread of social media and its direct effect on students. Otherwise, this will have a huge impact on the educational system.