bluuebunny/crossref_metadata_2025 huggingface dataset:
Mapping evidence on management of cervical cancer in sub-Saharan Africa: scoping review protocol
Authors: Zibako Petmore , Hlongwa Mbuzeleni , Tsikai Nomsa , Manyame Sarah , Ginindza Themba G.
Published: June 2021

Background

Cancer is a non-communicable disease and is the number 2 leading cause of death globally. Among all cancers, cervical cancer is the number 1 killer of women in low-income countries (LICs). Cervical cancer is a well understood preventable cancer. The rates of cervical cancer are very varied and inversely proportional to the effectiveness of disease management policies. Management of cervical cancer includes prevention, screening, diagnosis and treatment. The main objective of this scoping review is to map the evidence on cervical cancer management in sub-Saharan Africa (SSA) to understand the coverage of cervical cancer prevention and treatment services and provide an opportunity to generate knowledge on the risk factors, attitudes and practices extendable globally.

Methods and analysis

This review will be guided by Arksey and O’Malley’s framework recommended for conducting scoping review studies. The Preferred Reporting Items for Systematic Review and Meta-Analysis extension for Scoping Reviews (PRISMA-Scr) checklist will also be completed to ensure that the review adheres to the sound methodological rigour acceptable for scoping review studies. The following electronic databases will be searched for potentially eligible articles: PubMed, Ebsco Host, Scopus and Cochrane Database of Systematic Reviews. Study screening procedures recommended by Higgins and Deeks will be followed. A narrative synthesis will be used, with data synthesised and interpreted using sifting, charting and sorting based on themes and key issues.

Discussion

Cervical cancer can become a disease of the past with a proper control strategy in place. It is therefore imperative to map available evidence on the management of cervical cancer to inform policy and advocacy action. More knowledge on the status quo will guide policymakers in ensuring cancer management guiding policies are formulated/updated/revised accordingly.

Systematic review registration

Not registered with PROSPERO (not needed).

Protocol and registration

This scoping review was not registered.
A comprehensive scoping review of tibial cysts after anterior cruciate ligament reconstruction
Authors: Barbosa Nuno Camelo , Campos João Pedro , Capelão Vânia , Kandhari Vikram , Vieira Thais Dutra , Sonnery-Cottet Bertrand
Published: June 2021

Purpose

The purpose of this study was to perform a scoping review of published literature reporting on surgical management of tibial cysts which developed after ACLR.

Methods

A scoping review was conducted following the Arksey and O’Malley framework for scoping studies and Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) extension for scoping reviews (PRISMA-ScR) guidelines. A search strategy using the terms [“Tibial Cyst” AND “ACL”], [“Pretibial Cyst” AND “ACL”] was applied to the PUBMED database.

Results

Thirty-seven studies published between 1990 and 2019 were a part of this scoping review. Non-absorbable implants for tibial graft fixation were used in 10 studies (comprising a total 21 patients), while bio-absorbable implants were used in 27 studies (comprising a total 115 patients). Incidence of tibial cyst was reported in 3 studies (434 primary ACLRs) from whom 3.9% (n = 17) developed tibial cyst. Tibial cyst development in relation to use of bio-absorbable screws for tibial ACL graft fixation was reported in 16 studies (42.1%). Use of bio-absorbable screws with another factor was found to be related to tibial cyst development in another 1 study (2.6%). Most common symptoms were presence of mass or swelling, pain, tenderness, drainage, instability and effusion.

Conclusion

This scoping review demonstrated that tibial cysts is more frequently related to bioabsorbable screws, however it can also occur due to other causes. Current literature on tibial cyst after ACLR is of low-quality evidence. Future research is required to better understand aetiology, risk factors for cyst formation and the best possible mode of management.

Level of evidence

IV
Turkish anime viewers’ approach to Japanese cuisine culture
Authors: Basaran Guliz , Sunnetcioglu Serdar
Published: June 2021

It is seen that anime, which is a Japanese animation type, with the food scenes in it, cause the curiosity and interest of the anime viewers from different cultures towards Japanese cuisine. It is thought to contribute to Japan in terms of gastronomy. Accordingly, although there are many promotional and marketing tools to spread the products of Japanese cuisine culture to the world, the idea that anime with a large global viewers also have a share in this promotion is the starting point of this study. Within this context, in this study, it was aimed to research how animes affect the perception of Japanese cuisine culture in individuals. At the same time, informations about the foods they prefer belonging to this culture have been obtained. Interview technique which is one of the qualitative research methods was used for data collection. The interview questions were sent to 31 anime viewers by selecting the snowball sample method, through Google Forms, and the answers were collected between 2 February 2021 and 16 February 2021. Descriptive and content analysis was applied to the obtained data. According to the results of the research, it is seen that animes have a serious contribution to the reflection of the Japanese cuisine culture. While the interesting scenes in the food-themed animes enable the viewers to try Japanese food, it has been determined that they encourage to buy Japanese cuisine products and use them at home. In general, it was observed that animes made nearly half of the participants curious about Japanese cuisine and animes directed them to experience it.
SARS-CoV-2 infection and human semen: possible modes of contamination and transmission
Authors: Bhattacharya Koushik , Mukhopadhyay Lipika Das , Goswami Ratnadeep , Dutta Sulagna , Sengupta Pallav , Irez Tulay , Hamid Habibah Abdul , Syamal Alak Kumar
Published: June 2021

Background

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has turned into a global pandemic with multitudinous health impacts.

Main body

In light of the higher vulnerability of men to COVID-19 than women, there is rising concerns on the impact of SARS-CoV-2 infection on male fertility and possibilities of seminal contamination and transmission. The pandemic has attributed to the brief suspension of many fertility clinics and pathology laboratories, though many remained functional. Few reports reflect that SARS-CoV-2 can contaminate the semen of COVID-19 patients as well as that of recovering patients. The viral invasion into the testis may be due to the disrupted anatomical barriers of the testis by the inflammatory responses, and the persistence of the virus in the semen may be facilitated by the testicular immune privilege. Since SARS-CoV-2 is an enveloped RNA virus, it is also theoretically possible that this virus can remain viable in the semen samples even after cryopreservation with liquid nitrogen.

Conclusion

The present review emphasizes the possibilities of seminal dissemination of SARS-CoV-2 and thereby the chances of its sexual transmission. These perceptions and predictions are to facilitate immediate necessary actions to improvise the standard precautionary procedures for laboratory practices, including semen analysis or processing the semen sample for fertility treatments.
Are Cost-of-Care Conversations Best Practice? A Qualitative Study of Oncologists' Attitudes and Practice
Authors: Scott Allison M. , Harrington Nancy Grant
Published: June 2021

PURPOSE:

Patients' desire for cost conversations exceeds the incidence of such conversations, and many oncologists report avoiding cost conversations despite reporting willingness to have them. Our objective was to examine oncologists' attitudes toward cost conversations and how those attitudes affect practice.

METHODS:

An experienced investigator conducted individual interviews with oncologists practicing in Kentucky. Participants were asked about their attitude toward and experience with cost conversations and their advice for discussing cost with patients. Interview transcripts were analyzed by a four-member team using qualitative descriptive analysis to identify themes.

RESULTS:

Participants were 32 MDs (male = 68.8%) age 31-77 years who were board-certified in medical oncology (53.1%), surgical oncology (25.0%), or radiation oncology (21.9%). We categorized participants into two groups: (1) those who viewed cost conversations as best practice and reported pursuing such conversations (37.5%) and (2) those who viewed cost conversations as not best practice and reported avoiding them (62.5%). Our analysis revealed three parallel themes for each category: Cost conversation attitudes and practice were based on (1) making good treatment decisions, (2) being a good clinician, and (3) having a good relationship with patients.

CONCLUSION:

Not all oncologists view cost conversations as best practice. To improve cost conversation attitudes and practice, cost conversations can be framed as a strategic tool that—when used well—fosters optimal decision making, professionalism, and the therapeutic relationship.
Guido da Montefeltro and the Tyrants of Romagna in Inferno 27
Authors: Chida Nassime
Published: June 2021

This article uses historical scholarship on Guido da Montefeltro and medieval Romagna (Franceschini and Vasina) alongside Ovid’s Metamorphosis and the Serventese del 1277 to contextualize the question asked by the soul of Guido (about peace or war in Romagna) and the catalog of tyrants provided by the pilgrim in Inferno 27. It examines how Dante held Guido accountable for the intensification of warfare in Romagna and made an argument for the responsibility of military strategists in the consolidation of urban signorie. Dante’s assessment coincides with current historiography and shows his concerns about the formation of regional states. A recontextualization of Guido’s question reveals the targeted nature of the pilgrim’s response, in which the pilgrim presents Guido with the triumph of his enemies.
A Tale of Truth
Authors: De Vos Laurens
Published: June 2021

Laurens De Vos examines the ways in which director Milo Rau incorporates the poetic and aesthetic techniques of alienation theorized and pioneered by German director Bertolt Brecht for purposes similar to but distinct from Brecht’s. Like Brecht, De Vos argues, Rau exploits the “cesura between actor and character” to highlight the nature of the theatrical event for purposes that are largely social, drawing attention to systems of power, privilege, and violence. De Vos posits that unlike Brecht, however, Rau does not use these techniques to draw attention to the constructedness of the theatrical event—instead, Rau seeks to make the representation itself real, blurring the line between fiction and reality to trouble and implicate the audience.
Dez anos fomentando o uso de casos no ensino brasileiro de Administração: um balanço da GVcasos
Authors: Jayo Martin
Published: June 2021

O editor comenta a trajetória e realizações da GVcasos, por ocasião do décimo aniversário da revista.
ЛИЧНОСТНЫЕ И КОММУНИКАТИВНЫЕ АСПЕКТЫ ПРОЯВЛЕНИЯ АЛЕКСИТИМИИ
Authors: Kosinova Maria S. , Zubareva Nadezhda S.
Published: June 2021

Цель. Выявить связь алекситимии с показателями межличностных отношений и личностных особенностей.
Методы и методики исследования. Методы: теоретический анализ литературных источников; психологическое тестирование; математическая статистика: коэффициент ранговой корреляции Rs Спирмена. Методики: «Торонтская шкала алекситимии» TAS-20 (Toronto Alexithymia Scale – TAS-20-R; Г. Д. Тэйлор; адаптация: Е.Г. Старостина); «Тест на эмоциональный интеллект» (Н. Холл); «Многофакторный личностный опросник 16-PF» (Р. Кеттелл); «Диагностика помех в установлении эмоциональных контактов» (В.Бойко); «Опросник межличностных отношений» (Fundamental Interpersonal Relations Orientation – FIRO-B; В. Шутц; адаптация: А.А. Руковишников).
Результаты. В результате проведенной работы мы выяснили, что алекситимия взаимосвязана с личностными и коммуникативными особенностями студентов. Нам удалось выявить особенности проявления эмоционального интеллекта, черт личности, конкретных помех при установлении эмоциональных контактов, которые проявляются с повышением выраженности алекситимии в общей исследуемой группе студентов.
Область применения результатов. Результаты исследования могут быть применены для коррекции алекситимии и ее проявлений в межличностных отношениях студентов и при выстраивании контакта.
CONTINUITY IN THE CONTENT OF TEACHING PROJECT AND RESEARCH ACTIVITIES OF SCHOOLCHILDREN, BACHELOR'S AND MASTER'S STUDENTS ON THE EXAMPLE OF THE DISCIPLINE “FOREIGN LANGUAGE”
Authors: Kazanceva Elena , Noskova Marina
Published: June 2021

The article is devoted to the consideration of the process of the successive formation of metasubject results in the framework of project / research activities of students in the context of learning foreign languages. In this regard, the requirements for the degree of formation of metasubject skills formed within the subject of "Foreign language" at various levels of education and taking into account the stages of project activity (including research project) – goal setting, organization and planning, implementation, reflection, presentation. The article describes a project conducted by the Department of foreign languages and linguodidactics of Irkutsk state University called "the Future in the project", implemented in the framework of the subjects "Methodology of teaching foreign languages" at the University and "Foreign language" at school in order to implement the continuity of the content of teaching project/research activities of students at different levels of education.
Theoretical aspects of gender differences in stress tolerance in the profession of employees in police service
Authors: Kobysheva Tat'yana , Kostina Lyubov'
Published: June 2021

The article actualizes the problem of a high level of stress resistance of employees of internal affairs agencies who regardless of gender, must achieve the assigned tasks and carry out effectively operational and service activities in dangerous and extreme conditions. The article presents a theoretical analysis of the scientific views of domestic and foreign scientists of the problem of stress factors and gender differences in stress resistance, levels of stress in the operational activities of employees of internal affairs agencies. Some gender characteristics, stereotypes of feminine and masculine behavior are revealed. The psycho-applied aspects of the problem under study are reflected in the form of the results of psychological observations of the authors of the article on the behavior of employees of the internal affairs agencies according to which male and female employees do not always act according to gender stereotypes of behavior when they find themselves in difficult and dangerous situations. Taking into account the mixed nature of the service collectives of the subdivisions of the territorial bodies of the Ministry of Internal Affairs of Russia the need for an empirical study aimed at studying the stress resistance of female and male employees of the internal affairs bodies is justified. This study will make it possible to characterize psychological work as differential work, designed for the gender characteristics of employees of the of internal affairs agencies and aimed at developing their stress resistance as a professionally important quality.
IMPROVING THE PSYCHOLOGICAL RESISTANCE OF YOUNG PEOPLE TO MANIPULATIVE INFLUENCE ON THE INTERNET
Authors: Lazareva Irina , Miheev Evgeniy
Published: June 2021

Increasing psychological resistance to manipulative influence and preventing the involvement of minors in illegal activities with the help of information and communication technologies (ICTs) are important tasks of the State. The article analyzes some psychological mechanisms that contribute to manipulation on the Internet, including the effects of normative influence, conformity, perceived interpersonal similarity, cascades of available information, emotional contagion, hemophilicity, false memories, and multiple sources. The authors analyze the main strategies for promoting false and misleading information: artificial polarization, managing false accounts on behalf of public opinion leaders, creating emotional messages, using conspiracy theories, trolling aimed at provoking harassment of users on the network, defaming and delegitimizing opponents. Attention is also drawn to ways to counteract destructive information and psychological impact, which include not only ways to improve the legislative apparatus and the use of software and technical solutions, but also to increase the level of psychological stability of citizens, conducting preventive and preventive measures aimed at forming ideas about information threats, their types, methods of identification and protection, group norms and values. The author points out the need to develop and implement special psychological trainings and games created in the form of computer programs, mobile applications and online simulators in the socio-cultural and educational environment.
Professional stress resistance of employees of the security department of the penitentiary system
Authors: Potemkin Pavel
Published: June 2021

The dominant view of organizational change among employees is the concept that stress and resistance to stress are two independent phenomena, and that they are urgent and natural reactions to organizational change. Our article proposes a model of organizational change that views stress as a mediator between organizational change and resistance to change. According to this model, stress and resistance are not inevitable reactions to organizational change. It is more correct to find out what makes organizational change stressful or sensitive to employee resistance. The assumption is to implement strategies to reduce and resist negative stress and to increase the effectiveness of positive stress and resulting positive health outcomes among employees adapting to emerging change. Correctional officers are potentially exposed to more risk factors in the workplace because they are on a mission of sorts to contribute to public safety by actively helping offenders become law-abiding citizens. Among the main factors having destructive effect on the efficiency of professional activity of an employee of penitentiary system we consider the following to be necessary: lack of material and human resources, conflictogenicity of communication with convicts, feelings of anxiety due to professional activity. As protective factors, it is advisable to note measures of social support in the penitentiary environment, and the development of positive coping-strategies condition the improvement of the level of training of officers. As a result, prolonged work stress can lead to burnout in the workplace and is characterized by feelings of exhaustion, cynicism, detachment, ineffectiveness and lack of personal achievement. Both work stress and emotional burnout combined can lead to a decrease in officers' commitment to the core ideology of the institution and, consequently, a decrease in job performance.
Przekład literacki na cztery ręce, czyli o warsztacie niemieckiego tandemu tłumaczy Ksiąg Jakubowych Olgi Tokarczuk
Authors: Majkiewicz Anna
Published: June 2021

Literary Translation in Four Hands – the Workshop of the German Translation Tandem of Olga Tokarczuk’s The Books of Jacob

The Books of Jacob by Olga Tokarczuk, the Polish Nobel Prize winner in literature, was published in 2014 by Wydawnictwo Literackie (Krakow). The German translation of the novel is the result of the work of the tandem, Lisa Palmes and Lothar Quinkenstein, who by using the TOLEDO platform (Translators in Cultural Exchange) programme of the German Translators Fund, have made a “translation journal” entitled Die Funken der Erlösung. Journal zur Übersetzung des Romans Die Jakobsbücher von Olga Tokarczuk (Kampa) available. Its reading allows us to reconstruct the translation tandem’s successive activities in the preparation for the proper translation process: from the reconstruction of the boundary between history and fiction during the reading of the source texts, through the deconstruction of the image of the main character in the original and its reconstruction in the translation, to the exploration of the colour of the epoch, the polyphonicity and intertextuality of the novel and the definition of their translation strategies.
Geochemical Modeling of Scale Formation due to Cooling and CO2-degassing in San Kamphaeng Geothermal Field, Northern Thailand
Authors: Taweelarp Sutthipong , Suntikoon Supanut , Rojsiraphisal Thaned , Ploymaklam Nattapol , Saenton Schradh
Published: June 2021

Scaling in a geothermal piping system can cause serious problems by reducing flow rates and energy efficiency. In this work, scaling potential of San Kamphaeng (SK) geothermal energy, Northern Thailand was assessed based on geochemical model simulation using physical and chemical properties of hot spring water. Water samples from surface seepage and groundwater wells, analyzed by ICP-OES and ion chromatograph methods for chemical constituents, were dominated by Ca-HCO3 facies having partial pressure of carbon dioxide of 10–2.67 to 10–1.75 atm which is higher than ambient atmospheric CO2 content. Surface seepage samples have lower temperature (60.9°C) than deep groundwater (83.1°C) and reservoir (127.1°C, based on silica geothermometry). Geochemical characteristics of the hot spring water indicated significant difference in chemical properties between surface seepage and deep, hot groundwater as a result of mineral precipitation along the flow paths and inside well casing. Scales were mainly composed of carbonates, silica, Fe-Mn oxides. Geochemical simulations based on multiple chemical reaction equilibria in PHREEQC were performed to confirm scale formation from cooling and CO2-degassing processes. Simulation results showed total cumulative scaling potential (maximum possible precipitation) from 267-m deep well was estimated as 582.2 mg/L, but only 50.4% of scaling potential actually took place at SK hot springs. In addition, maximum possible carbon dioxide outflux to atmosphere from degassing process in SK geothermal field, estimated from the degassing process, was 6,960 ton/year indicating a continuous source of greenhouse gas that may contribute to climate change.

Keywords: Degassing, Geochemical modeling, PHREEQC, San Kamphaeng Hot Springs, Scaling
Race Thinking in Margaret Cavendish's Drama
Authors: Iyengar Sujata
Published: June 2021

Abstract: This essay uses an intersectional approach to identify in the drama of Margaret Cavendish, Duchess of Newcastle, the patterns that Hannah Arendt called "race thinking" and to extend Arendt's approach backwards in time as early as the seventeenth century. Famously, Cavendish—poet, playwright, personality—prided herself on her "singularity" or originality, from her cultivated eccentricity of dress to her insistence, which anticipates the Romantic movement, that her works come from her alone (down to her punctilious annotation of the occasional lines or stanzas or scenes composed by her husband and included in her plays). The combined authority Cavendish appropriates—rank and individual merit—and that she uses to transcend the restrictions placed on her by her gender makes Cavendish an apt instance through which to investigate how or whether merit and rank—and gender—can produce race thinking. I suggest that Cavendish's first play, the two-part Loves Adventures , simultaneously queers or questions heteronormative reproduction and the purity of an imagined bloodline or race and yet restricts the ability to transcend race (understood for Cavendish as bloodline and as gender) to those who can demonstrate merit or (to borrow Patricia Akhimie's invaluable formulation) "cultivation." Similarly, Cavendish's later play The Bridals uses crossor transgender casting and the potential for cultivation not to liberate but to humiliate and racialize its working-class characters. In The Female Academy , wealthy, aristocratic ladies literally become the gatekeepers and guarantors of education and bloodline. The intersectional hierarchies of rank, skin color, gender, and sexual autonomy thus triumph over an imagined innate or even a "cultivated" merit or virtue.
Smooth multifocal wavefronts with a prescribed mean curvature for visual optics applications
Authors: Barbero Sergio
Published: June 2021

Multifocal lenses comprising progressive power surfaces are commonly used in contact and intraocular lens designs. Given a visual performance metric, a wavefront engineering approach to design such lenses is based on searching for the optimal wavefront at the exit pupil of the eye. Multifocal wavefronts distribute the energy along the different foci thanks to having a varying mean curvature. Therefore, a fundamental step in the wavefront engineering approach is to generate the wavefront from a prescribed mean curvature function. Conventionally, such a thing is done by superimposing spherical wavefront patches and maybe adding a certain component of spherical aberration to each spherical patch in order to increase the depth-of-field associated with each focus. However, such a procedure does not lead to smooth wavefront solutions and also restricts the type of available multifocal wavefronts. We derive a new, to the best of our knowledge, mathematical method to uniquely construct multifocal wavefronts from mean curvature functions (depending on radial and angular coordinates) under certain numerically justified approximations and restrictions. Additionally, our procedure leads to a particular family of wavefronts (line-umbilical multifocal wavefronts) described by 2 conditions: (1) to be smooth multiplicative separable functions in the radial and angular coordinates; (2) to be umbilical along a specific segment connecting the circle center with its edge. We provide several examples of multifocal wavefronts belonging to this family, including a smooth variant of the so-called light sword element.
Photonic computing to accelerate data processing in wireless communications
Authors: Salmani Mahsa , Eshaghi Armaghan , Luan Enxiao , Saha Sreenil
Published: June 2021

Massive multiple-input multiple-output (MIMO) systems are considered as one of the leading technologies employed in the next generations of wireless communication networks (5G), which promise to provide higher spectral efficiency, lower latency, and more reliability. Due to the massive number of devices served by the base stations (BS) equipped with large antenna arrays, massive-MIMO systems need to perform high-dimensional signal processing in a considerably short amount of time. The computational complexity of such data processing, while satisfying the energy and latency requirements, is beyond the capabilities of the conventional widely-used digital electronics-based computing, i.e., Field-Programmable Gate Arrays (FPGAs) and Application-Specific Integrated Circuits (ASICs). In this paper, the speed and lossless propagation of light is exploited to introduce a photonic computing approach that addresses the high computational complexity required by massive-MIMO systems. The proposed computing approach is based on photonic implementation of multiply and accumulate (MAC) operation achieved by broadcast-and-weight (B

&

W) architecture. The B

&

W protocol is limited to real and positive values to perform MAC operations. In this work, preprocessing steps are developed to enable the proposed photonic computing architecture to accept any arbitrary values as the input. This is a requirement for wireless communication systems that typically deal with complex values. Numerical analysis shows that the performance of the wireless communication system is not degraded by the proposed photonic computing architecture, while it provides significant improvements in time and energy efficiency for massive-MIMO systems as compared to the most powerful Graphics Processing Units (GPUs).
Blood coagulation parameter abnormalities in hospitalized patients with confirmed COVID-19 in Ethiopia
Authors: Araya Shambel , Mamo Mintesnot Aragaw , Tsegay Yakob Gebregziabher , Atlaw Asegdew , Aytenew Aschalew , Hordofa Abebe , Negeso Abebe Edao , Wordofa Moges , Niguse Tirhas , Cheru Mahlet , Tamir Zemenu
Published: June 2021

Background

Coagulopathy and thromboembolic events are among the complications of Corona Virus disease 2019 (COVID-19). Abnormal coagulation parameters in COVID-19 patients are important prognostic factors of disease severity. The aim of this study was to analyze coagulation profiles of hospitalized COVID-19 patients in Addis Ababa, Ethiopia.

Methods

This prospective cross-sectional study was conducted among 455 Covid-19 patients admitted at Millennium COVID-19 care and treatment center, Addis Ababa, Ethiopia from July 1- October 23, 2020. Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT) and International normalized ratio (INR) were determined on HUMACLOT DUE PLUS® coagulation analyzer (Wiesbaden, Germany). In all statistical analysis of results, p<0.05 was defined as statistically significant.

Result

A prolonged prothrombin time was found in 46.8% of study participants with COVID-19 and a prolonged prothrombin time and elevated INR in 53.3% of study subjects with severe and 51% of critically COVID patients. Thrombocytopenia was detected in 22.1% of COVID-19 patients. 50.5% and 51.3% of COVID-19 patients older than 55 years had thrombocytopenia and prolonged APTT respectively.

Conclusion

In this study, prolonged prothrombin time and elevated INR were detected in more than 50% of severe and critical COVID-19 patients. Thrombocytopenia and prolonged APTT were dominant in COVID-19 patients older than 55 years. Thus, we recommend emphasis to be given for monitoring of platelet count, PT, APTT and INR in hospitalized and admitted COVID-19 patients.
Evaluation of Efficacy of Customized Lidocaine Bioadhesive Anaesthetic Patch for Extraction of Primary Tooth - An Invitro Study
Authors: Adyanthaya Amith , K Risana , Sivaraman Aparna , A Gopika Gopan , K. Nazreen Ayub , Aloysious Reshma , C.R. Sangeetha , Nair Swetha S.
Published: June 2021

BACKGROUND We wanted to clinically evaluate the efficacy of lidocaine bioadhesive patches for extraction in paediatric dentistry and assess the comfort and pain response by sound eye motor (SEM) scale and intensity of pain using the visual analogue scale (VAS). METHODS A total of thirty-five co-operative children of age group 8 - 12 years without systemic diseases who needed dental extraction participated in the study. Extraction was carried out using customized lidocaine bioadhesive patches as anaesthetic agent. Evaluation of comfort and pain response was done by sound eye motor scale and intensity of pain using the visual analogue scale. Statistical analysis was done with SPSS version 2.0. Comparison of SEM scale and VAS scores between different subgroups was done using a chi-square test. P value less than 0.001 was considered statistically significant. RESULTS Children of higher age groups belonging to both the genders demonstrated less perception to pain during extractions using lidocaine patch. During extraction of firm teeth and teeth with Grade I mobility, perception of pain was more in girls. Maxillary arch extraction in children with various grades of mobility perceived less pain. Irrespective of age, gender and arches,teeth with Grade II and Grade III mobility were extracted with minimal VAS and SEM score. CONCLUSIONS Bioadhesive patches serve as a potential non-invasive alternative to traditional modes of local anaesthetic delivery with the advantage of eliminating needle phobia and possible negative influence on the behaviour. KEY WORDS Bioadhesive Patches, Lidocaine, Extraction, Paediatric Dentistry
Case Report - A Rare Case of SLE Retinopathy
Authors: Dharamdasani Heena , Sudhakar Stephen
Published: June 2021

Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disorder. It has a relapsing and remitting course.1 It is found to be more common in Asian and African population. It is more common in females than males. Usual age of onset is between 15 years and 45 years.2 It occurs in one third of patients with SLE and is associated with morbidity. SLE can involve eyes, joints, brain, kidney, skin, serosa, ears, lung, and gastrointestinal tract. Manifestations in SLE occur due to recurrent vascular injury, which is secondary to immune complex deposition, thrombosis, leukothrombosis.3 Thrombotic complications are found to be more common in Caucasians.4 Ocular manifestations can be seen in one third of the population with SLE.1,5 Triggering factors such as exposure to sunlight, use of sulphonamides, pregnancy, infections, and contraception have been known to exacerbate the disease.2,6 Hallmarks of ophthalmic involvement in SLE include severe tear deficiency, retinal vasculopathy and scleral inflammation.3 Most common ocular presentation is keratoconjunctivitis sicca.7 Fundus examination in the eye is the only part of the body where the vasculature can be directly visualized and hence SLE retinopathy indicates the amount of systemic vascular damage, retinopathy indicates high disease activity in patients with SLE and hence indicates a poor survival of these patients.2 Most patients with SLE develop secondary Sjogren’s syndrome.
"Látható kéz" és innováció : Olasz iparági körzetek ma
Authors: Patik Réka
Published: June 2021

Az olasz iparági körzetek jelentős átalakuláson mentek át az utóbbi években. Ezek az átalakulások még nem értek véget, kimenetelük legalább akkora érdeklődésre tarthat számot, mint a körzetek '80-as és '90-es évekbeli sikerei. A nemzetközi szakirodalom már régóta jelzi a változásokat, melyek alapján három fejlődési út látszik körvonalazódni: az iparági körzetek belső átszerveződése, a körzetek eddig társadalmilag és gazdaságilag is zárt határainak megnyílása, valamint az intenzívebb, radikális innováció felé való elmozdulás. Az ezek közti választás egyben azt is meghatározza majd, mennyit képesek a körzetek megőrizni eddigi jellegzetes vonásaikból, ám ugyanez fordítva is igaz: az eddigi jellegzetességek, azaz a társadalmi beágyazottság, kulturális háttér befolyásolja, sikeressé válhat-e a választott fejlődési ú!JAz iparági körzetek tipikus vonásainak közgazdaságtani elméletek és különböző modellek alapján történő összegzése után főként azon jellegzetességeket és tendenciákat vizsgálja a tanulmány, melyeket a magyar régiók, köztük a Dél-Alföld számára is érdemes átgondolni.
Oblikovanje modela medpoklicnega sodelovanja medicinskih sester na področju zagotavljanja farmacevtske skrbi
Authors: Petrović Marko , Osmančević Benjamin , Ličen Sabina , Karnjuš Igor , Prosen Mirko
Published: June 2021

Uvod: Medpoklicno sodelovanje medicinskih sester pri zagotavljanju farmacevtske skrbi je pomembno z vidika zagotavljanja kakovosti zdravstvene oskrbe pacienta. Vendar pa vključevanje medicinskih sester v farmacevtsko skrb odpira tudi številna vprašanja, povezana z njihovim izobraževanjem ter posledično posedovanjem kompetenc za njihovo učinkovito vlogo pri zagotavljanju farmacevtske skrbi. Cilj raziskave je bil ugotoviti stališča zdravnikov, farmacevtov in medicinskih sester do vloge slednjih v medpoklicnem sodelovanju na področju farmacevtske skrbi v Sloveniji.Metode: Uporabljena je bila deskriptivna interpretativna metoda. V namenski kvotni vzorec je bilo vključenih 24 oseb: osem zdravnikov, osem farmacevtov in osem medicinskih sester. Podatki so bili zbrani z delno strukturiranimi intervjuji. Pridobljene podatke smo analizirali s pomočjo metode analize vsebine.Rezultati: Raziskava je razkrila, da medicinske sestre že sedaj opravljajo del nalog na področju farmacevtske skrbi in svojo vlogo vidijo tudi v nadaljnjih prizadevanjih za medpoklicno sodelovanje. Ugotovitve sicer kažejo, da zdravniki in farmacevti niso naklonjeni morebitnim profesionalnim kompetencam medicinskih sester, ki vključujejo področje zagotavljanja farmacevtske skrbi. Ob tem izpostavljajo zlasti znanje, ki ga po njihovem mnenju medicinskim sestram primanjkuje. Rešitev vidijo v vpeljevanju dodatnih izobraževanj s področja farmakologije. Medicinske sestre menijo, da so v okviru zagotavljanja farmacevtske skrbi zapostavljene oziroma neenakopravne.Diskusija in zaključek: Medpoklicno sodelovanje v okviru zagotavljanja farmacevtske skrbi je zelo pomembno in ima lahko pozitiven vpliv na rezultate zdravljenja, vendar morajo medicinske sestre pridobiti ustrezna dodatna znanja in posledično kompetence, se kontinuirano izobraževati, imeti vidnejšo vlogo v kliničnih raziskavah ter ne nazadnje v teh prizadevanjih tudi same prevzemati dejavnejšo vlogo.
Density of sets with missing differences and applications
Authors: Pandey Ram Krishna , Rai Neha
Published: June 2021

For a given set M of positive integers, a well-known problem of Motzkin asks to determine the maximal asymptotic density of M-sets, denoted by μ(M), where an M-set is a set of non-negative integers in which no two elements differ by an element in M. In 1973, Cantor and Gordon find μ(M) for |M| ≤ 2. Partial results are known in the case |M| ≥ 3 including some results in the case when M is an infinite set. Motivated by some 3 and 4-element families already discussed by Liu and Zhu in 2004, we study μ(M) for two families namely, M = {a, b,a + b, n(a + b)} and M = {a, b, b − a, n(b − a)}. For both of these families, we find some exact values and some bounds on μ(M). This number theory problem is also related to various types of coloring problems of the distance graphs generated by M. So, as an application, we also study these coloring parameters associated with these families.
Existence on solutions of a class of casual differential equations on a time scale
Authors: Zhao Yige
Published: June 2021

In this paper, we develop the theory of a class of casual differential equations on a time scale. An existence theorem for casual differential equations on a time scale is given under mixed Lipschitz and compactness conditions by the fixed point theorem in Banach algebra due to Dhage. Some fundamental differential inequalities on a time scale are also presented which are utilized to investigate the existence of extremal solutions. The comparison principle on casual differential equations on a time scale is established. Our results in this paper extend and improve some well-known results.
Reeb flow invariant ∗-Ricci operators on trans-Sasakian three-manifolds
Authors: Ma Rongsheng , Pei Donghe
Published: June 2021

In this paper, we investigate the ∗-Ricci operators on trans-Sasakian three-manifolds. We find conditions at which ∗- Ricci tensor on trans-Sasakian three-manifolds is symmetric and under which the ∗-Ricci operators are Reeb flow invariant.
COVID-19 u Srbiji između privatnog i javnog
Authors: Đorđević Belić Smiljana
Published: June 2021

U radu se razmatraju naracije o bolesti i bolovanju (engl. illness narratives) kao jedan od slojeva makronarativa COVID-19. Građa obuhvata sadržaje iz štampanih medija, TV emisija, sa društvenih mreža (Facebook, Instagram i YouTube), te naracije koje je autorka prikupila kroz intervjue. U fokusu razmatranja su žanrovski, tematski i pragmatički aspekti narativa o bolesti i bolovanju u različitim kontekstualnim okvirima. Narativi se posmatraju kroz prizmu koncepta biokomunikabilnih modela (Briggs i Hallin 2016). Pokazuje se da se gotovo svi primeri načelno dodiruju funkcijom konceptualizacije bolesti, jasno ili latentno prisutnim edukativnim usmerenjem, gotovo neizostavne su i procene funkcionisanja zdravstvenog sistema (između afirmacije i kritike), te komentari i opservacije vezane za aktuelno stanje sfere javnog zdravlja u najširem smislu. Očekivano, medijski izrazitije eksponirani i kroz višestruke interpretativne prizme propušteni sadržaji pokazuju se podložnijim za političku manipulaciju, dok u individualnim ličnim svedočenjima u prvi plan isplivavaju emocionalni doživljaji i sadržaji koji u oficijelnom diskursu ostaju zamagljeni ili potpuno skriveni i nevidljivi (problem stigmatizacije, traumatična sećanja vezana za krizne trenutke bolovanja, kritika zdravstvenog sistema i sl.). Pragmatičku slojevitost prati i izrazita heterofonija, u skladu sa istim odlikama makronarativa COVID-19 kao celine.
Zdravstveno stanje i borba protiv epidemija u Ličkoj pukovniji u 18. i 19. stoljeću
Authors: Balić Juraj
Published: June 2021

Sredinom 18. stoljeća na prostoru Hrvatsko-slavonske vojne krajine uspostavljeno je ukupno 11 krajiških pukovnija, vojnih, ali ujedno i teritorijalno-upravnih jedinica. Iako je glavna misao vodilja pri tom reformskom procesu koji su provodile središnje bečke vlasti bila u što većoj mjeri ujednačiti položaj krajišnika koji su nastanjivali taj golemi prostor koji se protezao uz granicu s Osmanskim Carstvom, pojedina krajiška područja su ipak u određenom pogledu zadržala svoju posebnost. U tome smislu Lička se pukovnija isticala kao jedino krajiško područje čije su se granice prostirale uz posjede čak dviju imperijalnih sila – Mletačke Republike i Osmanskog Carstva. Nadalje, radilo se o jednom od najslabije razvijenih krajiških područja u gospodarskom smislu, ponajviše zbog oskudice obradivog tla u tom brdovitom kraju. Međutim, karakteristično je također da je s toga teritorija potekao izuzetno kvalitetan vojni kadar koji je služio u habsburškoj vojsci. Vojna služba imala je i utjecaj na zdravlje ličkih krajišnika, što je i središnja tema ovoga rada. Na primjeru Ličke pukovnije razmotrit će se utjecaj zaraznih bolesti na živote krajišnika, kao i uloga ličkih krajišnika u sklopu habsburškog sanitarnog kordona tijekom 18. i 19. stoljeća.
8Th Century Musical Instrument on Kalasan Temple’s Relief
Authors: Pradoko Susilo , Widyastuti Maria Goretti , Fu’adi Fu’adi , Walidaini Birul
Published: June 2021

This research aims to unveil the types, size, figures, and functions of musical instruments carved as reliefs of Kalasan Temple as a way to revitalize the music from the 8th century. This research implements heuristic methods with Panofsky’s iconology analysis in three steps, which are pre-iconography, iconography, and iconology to analyse the reliefs of the Temple. The researchers validated the findings through forum group discussion with the Cultural Heritage Preservation Board of Yogyakarta. The findings show that (1) the relief of musical instruments in Kalasan temple is located on the head of Kala; (2) the musical instruments on the head are two wind instruments made of shells and a stringed instrument named vina; (3) there are two figures of musicians carved, which are two wind instruments players and a player of stringed instruments. The figures are depicted as heavenly creatures named Gandharva; (4) the measurement shows that the wind instruments have 35.98 cm length and 12.85 cm width, another one has 23.13 cm length and 12.85 cm width. Meanwhile, the stringed instrument has a length of 92.52 cm and 12.85 cm width; and (5) the musical instruments were performed to worship the Goddess of Tara.
Bach and Busoni Essentials in A Chaotic World
Authors: Lee Seow Phing , Ooi C. H. Raymond , Cheong Ku Wing
Published: June 2021

The study analyses the manifestation of structural change from the Bach Violin Chaconne (BWV1004, c.1720) to the Bach-Busoni piano transcription (c.1897). This article explores the use of two-dimensional music abstraction for vertical (pitch height) and horizontal (time) and its signal insignificant identified bariolage sections in music. Bariolage excerpts are chosen for they are implied sounds captured in repeatability and recontextuality. The first part of the article offers an excerpt of the Bariolage from violin at bars (113-120) and its parallel piano transcription at bars (118-125). Significant expressions of registral change utilizing different voice parts (Soprano, Alto, Tenor) offer a wider expansion with piano. These excerpts were chosen after reviewing the original Bach Chaconne and its essentials in analytical aesthetics for the projection of beauty in symmetry-asymmetry-chaos in composition. This study captures the aesthetics of the beautiful from the original score of the violin Chaconne at (bars 89-96) and (bars 113-120) for Bach-Busoni piano transcription. Further, there are recommendations for future studies to explore vertical spaces and mathematical sequences embedded in the music in other sections. The findings of this study were implied through new music analytical formats to be applied in composition, pedagogy, and performance practice.
Testosterone-induced increase in libido in a patient with a loss-of-function mutation in the AR gene
Authors: Marino Laura , Messina Andrea , S Acierno James , Phan-Hug Franziska , J Niederländer Nicolas , Santoni Federico , La Rosa Stefano , Pitteloud Nelly
Published: June 2021

Complete androgen-insensitivity syndrome (CAIS), a disorder of sex development (46,XY DSD), is caused primarily by mutations in the androgen receptor (AR). Gonadectomy is recommended due to the increased risk of gonadoblastoma, however, surgical intervention is often followed by loss of libido. We present a 26-year-old patient with CAIS who underwent gonadectomy followed by a significant decrease in libido, which was improved with testosterone treatment but not with estradiol. Genetic testing was performed and followed by molecular characterization. We found that this patient carried a previously unidentified start loss mutation in the androgen receptor. This variant resulted in an N-terminal truncated protein with an intact DNA binding domain and was confirmed to be loss-of-function in vitro. This unique CAIS case and detailed functional studies raise intriguing questions regarding the relative roles of testosterone and estrogen in libido, and in particular, the potential non-genomic actions of androgens.

Learning points

N-terminal truncation of androgen receptor can cause androgen-insensitivity syndrome.

Surgical removal of testosterone-producing gonads can result in loss of libido.

Libido may be improved with testosterone treatment but not with estradiol in some forms of CAIS.

A previously unreported AR mutation – p.Glu2_Met190del (c.2T>C) – is found in a CAIS patient and results in blunted AR transcriptional activity under testosterone treatment.