bluuebunny/crossref_metadata_2025 huggingface dataset:
Prospective randomized study comparing outcome of myocardial protection with Del-Nido Cardioplegia versus Saint Thomas Cardioplegia in adult cardiac surgical patients
Authors: Rizvi Muhammad Farhan Ali , Yousuf Syed Muhammad Arslan , Younas Attaullah , Baig Mirza Ahmad Raza
Published: January 2022

Objectives: To compare the effectiveness of Del-Nido cardioplegia as myocardial protective agent with Saint Thomas cardioplegia in adult cardiac surgical patients.

Methods: This prospective randomized study was conducted in cardiac surgery department of Bahawal Victoria hospital Bahawalpur, from October 2020 to March 2021. Eighty adult patients who underwent primary Isolated coronary artery bypass grafting (CABG) or isolated Valve surgery requiring cardiopulmonary bypass were randomly divided into Del Nido (DN, n=40) and Saint Thomas (ST, n=40) groups. Data regarding operative and post-operative variables such as cardiopulmonary bypass (CPB) and aortic cross clamp (AXC) times, inotropic requirements, resumption of sinus rhythm, need for electrical defibrillation, post-operative CKMB, blood requirement and ICU stay were noted.

Results: CPB and AXC times were statistically insignificantly different. Resumption of Sinus rhythm was seen significantly in more patients of DN group (95%) than in ST group (72.5%) [p-value 0.05]. Less patients of DN group (5%) were candidates of electrical defibrillation than ST group (17.5%) [p-value <0.001). Post- operative CKMB values were significantly lower in DN group as compared to ST group (30.5±22.6 IU vs 50.5±50.28 IU, p value.008). Blood transfusion was significantly lower in DN group; 50% versus 80% in ST group (p-value 0.005). Ventilation time was significantly less in DN group than ST group (165.95±48.09 minutes versus 165.95±48.09 minutes respectively, p-value 0.03). While ICU stay was also less in DN group; 5.2±0.8 days versus 6.05±1.6 days in ST group (p-value 0.003).

Conclusion: Del-Nido cardioplegia is a reliable and better myocardial protective agent than Saint Thomas cardioplegia in adult cardiac surgical procedures.

doi: https://doi.org/10.12669/pjms.38.3.4730

How to cite this:Rizvi MFA, Yousuf SMA, Younas A, Baig MAR. Prospective randomized study comparing outcome of myocardial protection with Del-Nido Cardioplegia versus Saint Thomas Cardioplegia in adult cardiac surgical patients. Pak J Med Sci. 2022;38(3):---------.  doi: https://doi.org/10.12669/pjms.38.3.4730

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Gynaecologists’ views on the management of Vaginal Vault Prolapse: A qualitative study
Authors: Al-Baghdadi Omaema , Barnick Christian , Srivastava Garima , Elbiss Hassan
Published: January 2022

Objective: This study examined gynaecologists’ experience and views on the management of vaginal vault prolapse (VVP) using laproscopic sarcocolpopexy (LSCP) versus open sarcocolpopexy (OSCP).

Methods: In a qualitative study conducted at the University of Surrey and Homerton University Hospital, UK, from 2016 to 2017, semi-structured interviews were conducted with 15 consultants experienced in minimal access surgery or urogynecology. Interviews were recorded and transcripts were analyzed using the qualitative description (QD) approach.

Results: Eight broad themes emerged: VVP management, LSCP for management of VVP, OSCP and vaginal surgery with or without mesh use in VVP management, laparoscopic training and support as well as surgeons’ attitude towards LSCP. All participants acknowledged the importance of LSCP in the management of post-hysterectomy VVP as benefits outweighed risks in their view. OSCP was considered suitable in very specific circumstances. Vaginal surgery could be an excellent alternative to OSCP bearing in mind long-term efficacy and sexual activity in young women. Most participants agreed with national recommendations to avoid use of mesh in vaginal surgery for VVP and expressed the view that it should be done in specialised centres by trained surgeons who do such operations.

Conclusions: This study showed that the acceptability of LSCP was dependent on participants’ experience and consideration of the balance between patient’s goals and potential risks. It provides useful guidance for future large-scale projects.

doi: https://doi.org/10.12669/pjms.38.3.5215

How to cite this:Al-Baghdadi O, Barnick C, Srivastava G, Elbiss HM. Gynaecologists’ views on the management of Vaginal Vault Prolapse: A qualitative study. Pak J Med Sci. 2022;38(3):---------. doi: https://doi.org/10.12669/pjms.38.3.5215

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The association of pre-existing comorbid conditions with COVID-19 severity and post-COVID complications; insights from South Asia
Authors: Saeed Sahrai , Rajani Ronak
Published: January 2022

doi: https://doi.org/10.12669/pjms.38.3.5719

How to cite this:Saeed S, Rajani R. The association of pre-existing comorbid conditions with COVID-19 severity and post-COVID complications; insights from South Asia. Pak J Med Sci. 2022;38(3):439-441. doi: https://doi.org/10.12669/pjms.38.3.5719

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Συσχέτιση βιοδεικτών καρδιακής ανεπάρκειας με τη λειτουργικότητα των αγγείων και τη νεφρική λειτουργία σε ασθενείς με καρδιακή ανεπάρκεια
Authors: Δημητρόπουλος Ευστάθιος
Published: January 2022

Στην μελέτη συμπεριελήφθησαν 143 σταθεροί ασθενείς με καρδιακή ανεπάρκεια ισχαιμικής αιτιολογίας και μειωμένο κλάσμα εξώθησης (LVEF) καθώς και 77 υγιείς μάρτυρες. Για την εκτίμηση της ενδοθηλιακής λειτουργίας χρησιμοποιήθηκε υπέρηχος υψηλής ευκρίνειας το FMD (Flow-mediated dilation) και για την εκτίμηση της αρτηριακής σκληρίας χρησιμοποιήθηκε το pulse wave velocity (PWV) το οποίο προσδιορίζει την ταχύτητα του σφυγμικού κύματος. Παρόλο που δεν υπήρχαν σημαντικές διαφορές στα δημογραφικά χαρακτηριστικά, τα επίπεδα του sST2 ήταν αυξημένα στην ομάδα της καρδιακής ανεπάρκειας σε σχέση με την ομάδα των υγιών μαρτύρων (15.8 (11.0, 21.8) ng/mL vs. 12.5 (10.4, 16.3) ng/mL; p < 0.001). Στην ομάδα της καρδιακής ανεπάρκειας παρατηρήθηκε θετική συσχέτιση των επιπέδων του sST2 με την ηλικία (rho = 0.22; p = 0.007) ενώ δεν παρατηρήθηκε συσχέτιση ανάμεσα στα επίπεδα του sST2 με το LVEF (rho = -0.119; p = 0.17) ούτε με το PWV (rho = 0.1; p = 0.23). Αξιοσημείωτο είναι ότι τα επίπεδα του sST2 ήταν αυξημένα σε ασθενείς με ΚΑ NYHA III [20.0 (12.3, 25.7) ng/mL] συγκριτικά με ασθενείς με ΚΑ NYHA II (15.0 (10.4, 18.2) ng/mL; p = 0.003) και αντιστρόφως ανάλογα σε σχέση με το FMD (rho = -0.44; p < 0.001) ακόμη και μετά την προσαρμογή για πιθανούς συγχυτικούς παράγοντες. Σε ασθενείς με χρόνια καρδιακή ανεπάρκεια ισχαιμικής αιτιολογίας, τα επίπεδα του sST2 ήταν αυξημένα και σχετίζονταν θετικά με το λειτουργικό στάδιο της ΚΑ σύμφωνα με την κατάταξη της Νέας Υόρκης. Παρατηρήθηκε μία αντίστροφη συσχέτιση μεταξύ του FMD και των επιπέδων του sST2, τονίζοντας την αλληλεπίδραση μεταξύ του δυσλειτουργικού ενδοθηλίου και παθοφυσιολογικών μηχανισμών της καρδιακής ανεπάρκειας.
Κρίσιμοι παράγοντες ανάληψης περιβαλλοντικών δράσεων στα σχολεία
Authors: Γκερμπεσιώτη Γραμματία , Τσιρούκης Αχιλλέας , Κύδρος Δημήτριος , Μπλάνας Γεώργιος
Published: January 2022

Η περιβαλλοντική εκπαίδευση ως αντικείμενο έρευνας της διεθνούς επιστημονικής κοινότητας δεν είναι πρόσφατη. Ωστόσο, οι περισσότερες έρευνες ασχολήθηκαν με τα αποτελέσματα της περιβαλλοντικής εκπαίδευσης ή τις διαφορετικές διδακτικές μεθοδολογίες και ελάχιστα με τη διερεύνηση της επιρροής των μορφών διοίκησης, οργάνωσης και δικτύωσης της σχολικής μονάδας και των εκπαιδευτικών στην αποτελεσματικότητα των προγραμμάτων και έργων περιβαλλοντικής εκπαίδευσης. Η παρούσα ανασκόπηση της διεθνούς βιβλιογραφίας αποτυπώνει με συστηματικό τρόπο  τους κρίσιμους παράγοντες που ωθούν ή απωθούν τους εκπαιδευτικούς από το να συμμετάσχουν σε προγράμματα περιβαλλοντικών δράσεων. Η ανασκοπική έρευνα και μετα-ανάλυση αποκαλύπτει ότι οι συχνότερα απαντώμενοι παράγοντες είναι οι ακόλουθοι: κίνητρα των εκπαιδευτικών, η κοινωνική τους δικτύωση,  το στυλ ηγεσίας, το σχολικό κλίμα, αλλά και η οργανωσιακή κουλτούρα των σχολείων.
Comparing oral health systems for children in six European countries to identify lessons learned for universal oral health coverage: A study protocol.
Authors: McAuliffe Úna , Woods Noel , Barrett Shauna , Cronin Jodi , Whelton Helen , Harding Máiréad , Eaton Kenneth , Burke Sara
Published: January 2022

Background: Oral diseases have the highest global prevalence rate among all diseases, with dental caries being one of the most common conditions in childhood. A low political priority coupled with a failure to incorporate oral health within broader health systems has contributed to its neglect in previous decades. In response, calls are emerging for the inclusion of oral health within the universal healthcare domain (UHC). This protocol outlines the methodology for a cross-country comparative analysis of publicly funded oral health systems for children across six European countries, reporting on oral health status in line with the indicators for UHC.

Methods: This study will follow Yin’s multiple case study approach and employ two strands of data collection, analysis, and triangulation: a systematic documentary analysis and semi-structured interviews with elite participants local to each country. The countries chosen for comparison and providing a representative sample of European dental systems are Denmark, Hungary, the Republic of Ireland, Germany, Scotland, and Spain. A systematic search of five electronic databases and four additional electronic resources will be undertaken, in addition to grey literature and other publicly available sources, with the outcomes verified and further informed by local experts. The WHO Universal Health Coverage Cube will be used to guide data collection and analysis.

Conclusions: This research will provide policy makers with an in-depth analysis and comparison of publicly funded oral health systems for children in Europe, including consideration of effective preventive strategies, oral health system reform, and indicators of universal oral health coverage. It is anticipated that the outcomes may help in positioning oral health on governmental health agendas and support its integration into wider health systems’ reform in an accessible and affordable manner.
Nutrition of primary school children: world and Ukrainian realities
Authors: Vatan M. , Babienko V. , Levkovska V.
Published: January 2022

The aim of the study is to assess the actual nutrition of primary school children in Ukraine and other countries. Material and methods. An analysis of publications in scientific journals and reports of national agencies on the state of nutrition of primary school children. Search depth 10 years. The following search strategy "primary school", "nutrition", "sentinel surveillance" was used. The 15 most relevant publications were selected for further analysis. In addition, a survey of 450 primary school students was conducted on the quality of nutrition during school. Statistical processing was performed using MedCalc software.

Results. Most countries in the world have some kind of nutrition program for younger students. At the same time, the diets that these programs offer do not always meet the principles of healthy eating. According to our own data, only 96 (21.3%) of the surveyed schoolchildren aged 6-10 had a full meal at school. For the rest, there was either a qualitative or quantitative discrepancy in the composition of breakfast and lunch at school. The children noted the lack of time for meals, low taste of school lunches. Every second child consumed insufficient volume of fluids during school.

Conclusion. The nutritional status of primary school children is affected by lack of time for eating and recreational physical activity, unbalanced diet when using home lunch boxes and low coverage of high school students with organized meals. Unlike other countries, the main problem for Ukraine is not an energy surplus diet, but the popularity of fast food among children of primary school age is undoubtedly unacceptable.
Living With Floods: A Comparative Assessment of Resilience to Floods in Tal and Diara Regions of Malda District, West Bengal
Authors: RISHI HIRANMAY , Purkayastha Subrata
Published: January 2022

Tal and Diara regions of Malda district are extremely prone to floods, still, report higher population density than the state's average density. This indicates that the local population has learned to live with floods by developing resilience to the flood threat through better preparedness, coping, and adaptive strategies. Such micro-level strategies developed by the local people can be useful to policymakers and social scientists alike in terms of better mitigating the flood menace and associated vulnerability. This paper attempts to measure and compare the level of flood resilience of the local people living in Tal and Diara at the household level. Furthermore, the article aims to analyse whether the distance from the major flood-causing rivers, viz. Fulhar in Tal and Ganga in Diara play a role in the degree of resilience of the population to floods. The paper is empirical, where information has been collected from sample households and focus group discussion with village elders in two sets of villages, i.e., Maniknagar and Ratua in Tal and Gopalpur and Nurpur in Diara. The UNDP technique has been used to compute the composite Resilience Index (RI) consisting of Preparedness Index (PI), Immediate Coping Index (ICI), and Adaptive Index (AI). The findings suggest that the villages located in and around the levees of major flood-causing rivers, viz. Maniknagar in Tal and Gopalpur in Diara records a higher level of resilience to floods in comparison to the interior villages, viz. Ratua in Tal and Nurpur in Diara. The paper concludes that in both Tal and Diara, people have learned to cope and adapt to floods and that the closer the distance from the major flood-causing rivers, the higher the villagers' resilience to flood hazards.
A Study on the Bioresources of the Loktak Lake, Manipur (India) for Livelihood by the People Living in Five Villages Located in and Around the Lake
Authors: Laishram Jogesh
Published: January 2022

In this paper different bioresources of the Loktak lake linked to the livelihood of the communities residing in the periphery of the lake is investigated using questionnaire survey and purposive sampling technique in 300 households from five selected villages. Identification of species and data analysis was taken up using appropriate methodologies. In all 38 type of fishes, 1 type of prawn, 2 type of mollusca, 1 type of mussel, 16 type of vegetables, 8 type of fodders, 6 type of fuelwoods, 3 type of thatch grasses, 12 type of plants with medicinal properties and 2 type of handicraft items were found used by the villagers from Loktak lake for consumption and household earning. People of the survey villages were found to be poor and depended on the lake’s resources for consumption and household financial earning. In some of these villages certain bioresources has been responded to be lost. The resources of the lake have been found degrading because of several anthropogenic activities. Suitable policies and conservation measures involving the villagers needed to be adopted urgently by the concerned authorities for the protection and long term management of the lake and its bioresources.
Moisture-associated skin damage: an overview of management
Authors: Mitchell Aby , Hill Barry
Published: January 2022

Aby Mitchell and Barry Hill explain how nurses can treat this condition common in the elderly
Latest clinical research
Authors: Greener Mark
Published: January 2022

Mark Greener summarises the latest studies relevant to primary care nurses
Home care professionals’ views on working conditions during the COVID-19 pandemic: the case of Ireland
Authors: Mercille Julien , Edwards Justin , O’Neill Nicholas
Published: January 2022

This article examines home care professionals’ views on working conditions during the COVID-19 pandemic. In particular, it identifies similarities and differences between private, public and non-profit providers. The article seeks to shed light on the impacts of marketisation/privatisation on working conditions during the pandemic. Statistical tests on 350 questionnaires received from care workers in Ireland demonstrate the difficult working conditions during COVID-19 and variations by type of employer. We discuss an apparent ‘return of the state’ in home care provision during the pandemic, which may have dampened differences between types of providers.
España y la batalla de Annual en El poema de Dhar Oubarran. (Epopeya poética rifeña de 1921)
Authors: Abrighach Mohamed
Published: January 2022

En este artículo se intenta estudiar la visión local que se tuvo de la batalla de Annual y de los españoles en El Poema de Dhar Oubarran. El discurso de la alteridad que este poema encierra no se basa en los prejuicios denigratorios, sino en los comportamientos y acción llevada por España en el campo de batalla. En este sentido, se insiste, por un lado, en la facilidad con que los combatientes rifeños triunfaron usando armas muy convencionales, y, por otro, en la denigración del papel traidor desempeñado por los llamados «amigos de España», en su apoyo a la ocupación colonial y la correspondiente exaltación de la participación de la mujer en los campos de batalla aportando ayuda a la resistencia. A ello se añade, la dimensión brutal y violenta de los bombardeos de la aviación y el sentimiento trágico con que la voz poética vivió la destrucción provocada por ellos.
Marruecos, 1911: en torno a la crisis de Agadir y las crónicas de Abdelkrim en El telegrama del Rif (mayo-noviembre de 1911)
Authors: Velasco de Castro Rocío
Published: January 2022

Este trabajo pretende contribuir al estudio de la historia de las relaciones hispano-marroquíes y de la figura de Abdelkrim, Personaje controvertido que pasó de cantar las virtudes de la empresa colonial española a combatirla. El trabajo, que aúna el enfoque histórico con el filológico, tiene como objetivos analizar las repercusiones en clave interna e internacional de la denominada crisis de Agadir y enmarcar en este contexto la labor del rifeño como cronista en El Telegrama del Rif. Partiendo del contexto histórico que desembocó en dicho episodio, considerado por un lado como la antesala del tratado franco-marroquí de Fez de 1912, y por otro como antecedente de la primera guerra mundial, el texto realiza una primera aproximación a la contribución de Abdelkrim a la difusión de la posición española a través de sus crónicas, todas ellas escritas en árabe. Con ello se pretende ofrecer una muestra de cómo un medio de carácter militar y colonialista justificó las actuaciones españolas durante la crisis y en qué medida la inestimable colaboración de Abdelkrim ayudó a ello.
desarrollo de la relación China-Francia
Authors: Rocha Pino Manuel de Jesús
Published: January 2022

En la investigación se analizan los principales elementos estructurales que ha desarrollado la relación sino-francesa a partir de sus políticas de reconocimiento mutuo, así como la percepción en Francia sobre la instrumentación de la Iniciativa Cinturón y Ruta de la Seda en su territorio. Desde el establecimiento de sus relaciones diplomáticas en 1964, la relación sino-francesa ha sido instrumentada de acuerdo con algunos intereses nacionales que han definido sus características estructurales: 1) el interés de Francia por mantener una relación «privilegiada» con China en el contexto europeo; 2) el interés por mantener relaciones comerciales activas; 3) el interés de China por ser reconocida por una potencia occidental (económica, cultural, nuclear y perteneciente al Consejo de Seguridad de Naciones Unidas); 4) el interés de Francia por ser una orientadora de las políticas de la Unión Europea hacia China. En la investigación se identifica cómo estas características han sido instrumentalizadas por los distintos gobiernos de la República Francesa y la percepción generada por los gobiernos de la República Popular China.
Munkapiaci trendek a koronavírus-járvány idején
Authors: Pirohov-Tóth Barbara
Published: January 2022

A koronavírus-járvány megjelenése szignifikáns hatást gyakorol a világ gazdasági folyamataira és a társadalom egészére egyaránt. A folyamatos működés érdekében a legtöbb vállalat lehetővé tette munkavállalóinak, hogy munkájukat otthonról végezhessék. Annak érdekében, hogy pontosabb képet kaphassunk a koronavírus járvány munkaerő-piaci szereplőkre gyakorolt hatásáról, kvantitatív kutatást végzett a szerző. A közösségi média segítségével, online közzé tett kérdőív kiváló lehetőséget nyújtott számára, hogy a lakosság egy részének véleményét megismerhesse a témával kapcsolatban. A kapott válaszok eredményei pedig jelentős mértékben hozzájárultak ahhoz, hogy feltárja a COVID-19 vírus munkaerőpiacra gyakorolt hatását és az érintettek home office-hoz való hozzáállását, tapasztalatait. Kutatási eredményei alapján arra a következtetésre jutott, hogy a jövőben a munkáltatók és a munkavállalók szoros együttműködése hozzájárulhat ahhoz, hogy a válság által okozott károkat felszámolják és elősegíthessék a foglalkoztatás újbóli fellendítését.
A szolgáltató robotok definiálása és alkalmazási lehetőségei az üzleti szervezetekben. Szisztematikus irodalmi áttekintés
Authors: Pistrui Bence , Harmat Vanda
Published: January 2022

A szolgáltató robotok egyre szofisztikáltabb feladatokat képesek ellátni mind a fizikai, mind a kognitív tevékenységek tekintetében. Az irántuk való kereslet világszinten növekszik, amit jól alátámasztanak azok az előrejelzések is, melyek alapján 2025-re a fogyasztói interakciók 85 százaléka emberi alkalmazott nélkül fog zajlani. A szolgáltató robotok bevezetése tehát egyre elterjedtebbé válik a különböző iparágakban. Jelen cikk célja a szolgáltató robotok definiálása és alkalmazási lehetőségeik áttekintése, melyhez szisztematikus irodalomkutatást végeztek a szerzők. A cikkben a bevezetést követően bemutatják az irodalomkutatás módszerét, majd meghatározzák a szolgáltató robotok fogalmát az áttekintett irodalomban fellelt definíciók szintetizálásával. Továbbá összefoglalják a szolgáltató robotok által betölthető munkaköröket és az általuk elvégezhető feladatokat.
Teori Ring Structure Raimond Farrin dan Aplikasinya pada Q.S. Al-Baqarah
Authors: Solahuddin Ahmad
Published: January 2022

Many scholars are confused with the structure of the Koran. In fact, Bell states that the Qur'an needs to re-arrangement because its structure is unstructured. However, that is what later became an attraction for Islamic studies scholar, which denied the Bell thesis and found the structure of the Koran. Next, the study of the structure of the Qur'an is growing rapidly. The final theory of this study is the ring structure theory developed by Raimond Farrin. This paper will focus on discussing Farrin's ring structure theory applied in Sura al-Baqarah. In the end, the authors conclude: Farrin is a scholar in the field of Arab studies who focus on studying classical, middle Arabic literature and the Koran by using ring structure theory. The ring structure theory follows the structuralism paradigm developed by F. De Saussure. The basic assumption of this theory is that humans have an instinct for strucuture, as well as in literature or the like. For literary works, even scripture, structure is important to understand, because meaning is based on this structure. Next, Structure text refers to three models: parallesime (ABAB), Chiasm (ABBA) and concentrisme (ABCBA). In the end, Farrin managed to find the ring in Q.S. al-Fātiḥah, al-Baqarah, al-Anfal, al-Taubah, al-Rahman and al-Nas.[Banyak sarjana yang bingung dengan struktur al-Qur’ān. Bahkan, Bell pada akhirnya menyatakan bahwa al-Qur’ān butuh ditata ulang karena strukturnya tidak terstruktur. Namun, hal itulah yang kemudian menjadi daya tarik bagi sarjana studi Islam, yaitu membantah thesis Bell dan menemukan struktur al-Qur’ān. Berikutnya, studi mengenai struktur al-Qur’ān pun berkembang pesat. Adapun teori terakhir dari studi ini adalah teori ring structure yang dikembangkan oleh Raymond Farrin. Tulisan ini akan fokus untuk mengulas teori ring structure Farrin yang diaplikasikan dalam surat al-Baqarah. Pada akhirnya, penulis menyimpulkan: Farrin adalah sarjana dalam bidang Arab studies yang fokus mengkaji susastra Arab Klasik, pertengahan dan al-Qur’ān dengan menggunakan teori ring structure. Teori ring structure sesungguhnya mengikuti madzhab structuralisme yang dikembangkan oleh F. De Saussure. Asumsi dasar dari teori ini adalah: bahwa manusia memiliki naluri terhadap strucuture, begitu juga dalam bersastra atau sejenisnya. Untuk karya sastra, bahkan kitab suci, structure adalah hal penting untuk difahami, karena makna didasarkan pada structure ini. Berikutnya, Structure teks mengacu pada tiga model: parallesime (ABAB), Chiasm (ABBA) dan concentrisme (ABCBA). Pada akhirnya, dalam studinya Farrin berhasil untuk menemukan ring dalam Q.S. al-Fātiḥah, al-Baqarah, al-Anfal, al-Taubah, al-Rahman dan al-Nas.]
Determinan Foreign Direct Investment (FDI) di Negara-negara Organisasi Kerjasama Islam (OKI) Periode 2010-2019
Authors: Mahendra Weri
Published: January 2022

This study explains how the influence of GDP, exports, HDI, corruption perception index and democracy index on Foreign Direct Investment (FDI) in 15 OIC countries, namely Kazakhstan, Saudi Arabia, Indonesia, Turkey, Malaysia, United Arab Emirates, Azerbaijan, Egypt, Nigeria, Lebanon, Morocco, Tunisia, Bangladesh, Pakistan, Albania in 2010-2019. The existence of Foreign Direct Investment in a country can be useful as state revenue from tax sources, as well as the relationship between technology transfer, transfer of management expertise, development of entrepreneurial output and increasing the rate of national income in the economy. This study uses quantitative methods with secondary data and data collection through the World Bank, Transparency International, United Nations Development Program (UNDP) and The Economist Intelligence Unit. This study also uses panel data regression with the best model approach, namely the Random Effect Model (REM), to determine how much influence the independent variables such as GDP, exports, HDI, corruption perception index and democracy index have on the dependent variable (FDI). Based on the results of the F test obtained, it shows that in general the five independent variables have a positive and significant effect on FDI. Meanwhile, the T test results show that the GDP and export variables have a positive and significant effect on FDI. In the HDI variable, the corruption perception index and the democracy index have no effect on FDI.[Penelitian ini menjelaskan bagaimana pengaruh PDB, ekspor, IPM, indeks persepsi korupsi dan indeks demokrasi terhadap Foreign Direct Investment (FDI) di 15 negara OKI yaitu Kazakhstan, Arab Saudi, Indonesia, Turki, Malaysia, Uni Emirat Arab, Azerbaijan, Mesir, Nigeria, Libanon, Moroko, Tunisia, Bangladesh, Pakistan, Albania pada tahun 2010-2019. Adanya Foreign Direct Investment  dalam suatu negara dapat bermanfaat sebagai penerimaan negara dari sumber pajak, serta adanya hubungan alih teknologi, transfer keahlian manajemen, perkembangan wirausaha output serta menaikkan laju pendapatan nasional dalam perekonomian. Penelitian ini menggunakan metode kuantitatif dengan data sekunder dan pengambilan data melalui World Bank, Transparency International, United Nations Development Programme (UNDP) dan The Economist Intelligence Unit. Penelitian ini juga menggunakan regresi data panel dengan pendekatan model terbaik yaitu Random Effect Model (REM), untuk mengetahui seberapa besar pengaruh variabel bebas seperti PDB, ekspor, IPM, indeks persepsi korupsi dan indeks demokrasi terhadap variabel terikat (FDI). Berdasarkan hasil uji F yang diperoleh, menunjukkan bahwa secara umum kelima variabel bebas berpengaruh positif dan signifikan terhadap FDI. Sedangkan pada hasil uji T menunjukkan bahwa variabel GDP dan ekspor berpengaruh positif dan signifikan terhadap FDI. Pada variabel HDI, indeks persepsi korupsi dan indeks demokrasi tidak memiliki pengaruh terhadap FDI.]
Melatonin, A Promising Therapeutic for Diabetes Mellitus and Its Complications: A Narrative Review
Authors: Tursinawati Yanuarita , Kartikadewi Arum , Kartikadewi Arum , Yuniastuti Ari , Yuniastuti Ari , Susanti R
Published: January 2022

Diabetes mellitus (DM) is a non-communicable disease and still a health problem in the world. Melatonin is responsible to metabolize carbohydrate and regulate blood sugar levels. Several studies proved Melatonin is useful in the diabetes therapy and its complication by performing antioxidant activity through various signaling pathways. The role of the melatonin hormone in the pathogenesis of complications of diabetes mellitus is still a lot of controversy. Animal studies are still incomplete to explain the mechanism of action of melatonin. Therefore, this review aims to discuss Melatonin role administration in DM and its complications. This review was started by searching articles using electronic databases such as Google Scholar, Science Direct, SpringerLink and Pubmed between 2009-2019. Melatonin increased respiration within mitochondria; acted as antioxidant that fight free radical production; and reduced oxidative stress. It diminished proinflammatory cytokines in diabetes and prevents various DM complications on eyes, cardiac and male reproductive organs through antioxidant effects. It inhibited proinflammatory within several signaling Pathways, included PI3K/Akt-Nrf2,cGMP-PKG, Nrf-2-HO-1 and MAPK, Syk, p38MAPK pathways. There are various melatonin roles in diabetes and DM complications as a promising new breakthrough of DM treatment. It is necessary to explore Melatonin role in other DM complications. Most of this research is on experimental animals, thus clinical trial studies should be carried out in humans to make melatonin a promising therapeutic or prevention for diabetes and its complications in the future
Community Perception and Participation of the Forestry Partnership Scheme on PT. Restorasi Ekosistem Indonesia Working Area in Jambi Province
Authors: Herwindo Erwin , Rosyani Rosyani , Achmad Eva
Published: January 2022

Granting legal access to PT. REKI in ex. PT. The Asialog concession area in 2010 was marked by resistance accompanied by violence and claims by community groups (claimer). Conflict resolution with the Forestry Partnership approach resulted Forestry Partnership Recognition and Protection (Kulin KK) agreements for 79 heads of households who were members of 4 (four) groups. The question of this research is how the perceptions and participation of Kulin KK holders and the relationship between the two variables. The objectives of the study are to analyse the perceptions and participation and the relationship of its variables. This research is descriptive with a quantitative approach. The sampling technique used the census method with many respondents and 75 holders of legal access to Kulin KK. Perception and participation analysis and categorisation use 3 (three) point Likert scale and the score interval equation. The analysis of the relationship between perception and participation variables uses the Spearman correlation analysis. The results showed that the public perception of the provisions of the Forestry Partnership scheme was in the high category of 96% and 4% in the medium category, while the level of community participation was in the high category of 36%, 24% medium and 40% low. Perception and participation are negatively related.
Water Quality Index Analysis for Water Drinking and Irrigation in the Sumowono Groundwater Basin
Authors: Putranto Thomas Triadi , Susanto Novie , Pangestuti Dina Rahayuning , Putro Aji Bagas
Published: January 2022

The Sumowono Groundwater Basin is a cross-district basin located in Central Java Province, between Temanggung Regency, Kendal Regency, and Semarang Regency. The people in this area obtain fresh water from either dug wells or springs. The purpose of this research is to determine the feasibility of groundwater for drinking water and irrigation purposes. The method used was hydrogeological mapping and physical and chemical analysis of 10 groundwater samples. The samples were subjected to empirical testing of the Groundwater Quality Index to determine the feasibility of drinking water and irrigation using Sodium Adsorption Ratio (SAR) analysis and Wilcox diagram. The results showed that all samples physically have tasteless and odorous properties. For the chemical properties produced in the ten samples, the pH value ranges from about 6.85 - 7.27. The electrical conductivity is between 71.6 - 511 µS/cm. Total Dissolved Solids values are between 45.82 and 327.04 mg/L, with total hardness values ranging from 10 to 170 mg/L. From the results of the SAR analysis, it is found that the groundwater classes were included in S1C1 and S1C2, so that groundwater has low alkaline in both sodium and salinity, respectively. Thus, groundwater is considered suitable for consumption and irrigation purposes,
Home Biogas Production using Homemade Bio-activator with Chicken Manure
Authors: Surianto Heru , Raharjo Slamet , Wulandari Suci
Published: January 2022

The previous experiment was obtained that homemade activator is the best activator to produce biogas by using food waste consist of vegetable, fruit and rice waste.  The current research is carried out by adding chicken manure as a co-activator. Chicken manure content rich in nitrogen can be significantly enhance biogas production. This study is expected to increase the biogas production. There are two processes conducted at the laboratory scale, batch and semi-continuous process. The batch process aim to activate bacteria. The ratio set at food waste/chicken manure, 2 : 1 of digester #1, 3 : 1 of digester #2, 4 : 1 of digester #3 and digester control using food waste only. Stage two aims to produce biogas by adding food waste for 6 days periodically.  The ratio is set at food waste/water, 1 : 2. The highest biogas yielded is digester 2 with a cumulative volume biogas 120.77 liters consist of 71.01% CH4, 26% CO2, 2.9% O2 and 0.088% H2S. The potential of methane gas produced is 0.87 kWh and methane volume per TS and VS at around 18.72 L/kg and 34.68 L/kg, respectively.
Utilization of Spent Nickel Catalyst as Raw Material for Ni-Rich Cathode Material
Authors: Nisa Shofirul Sholikhatun , Nurohmah Anisa Raditya , Yudha Cornelius Satria , Nilasary Hanida , Nursukatmo Hartoto , Dyartanti Endah Retno , Purwanto Agus
Published: January 2022

Spent nickel catalyst will be harmful to the environment if it is not processed or used properly. In fact, this waste still has a high nickel content. The treatment of spent nickel catalysts has been widely reported, but limited to nickel extraction. Since the lithium-ion batteries demand is continued to increase, then nickel is the most sought-after metal. Consequently, nickel from spent nickel catalysts could be developed as secondary source for lithium-ion battery cathode. This study aims to utilize spent nickel catalysts into more valuable materials. Nickel that has been extracted and mixed with Mn and Co has been used as raw material for nickel-rich cathode, namely NMC. Nickel extraction and NMC synthesis were using the acid leaching method followed by co-precipitation[WI1] [SSN2] . Based on the functional test performed in this work, nickel from spent nickel catalyst can be applied to Li-ion batteries. The sintering temperature that gives good characteristics and electrochemistry was found 820oC. The galvanostatic charge-discharge test gave specific capacity results for NMC of 110.4 mAh/g. The cycle test showed that NMC synthesized from spent nickel catalyst can be carried out up to 50 cycles with a capacity retention of 87.18%.
Potencial bioativo, antioxidante e antimicrobiano do extrato aquoso do processo de extração do óleo essencial de folhas de Croton blanchetianus Baill
Authors: Cardoso de Vasconcelos Elayne , Gomes Ferreira Maria Jaiana , Clecia de Sousa Menezes Rayanne , Rodrigues Muniz Celli , Morais Ribeiro da Silva Larissa , Altina Teixeira de Figueiredo Evânia , Maria Falcão de Aragão Gláucia
Published: January 2022

O Croton blanchetianus Baill, conhecido como marmeleiro, é rico em metabólitos secundários, como alcalóides e terpenos, que podem apresentar efeitos biológicos. Desta forma, este estudo teve como objetivo avaliar o potencial bioativo, antioxidante e antimicrobiano dos extratos aquosos resultantes do processo de extração do óleo essencial das folhas frescas e secas do C. blanchetianus. O óleo essencial foi extraído por hidrodestilação e posteriormente o extrato aquoso foi coletado e liofilizado, sendo submetido às análises. A determinação da Concentração Inibitória Mínima e Concentração Bactericida Mínima contra bactérias patogênicas de interesse em alimentos (Staphylococcus aureus, Listeria monocytogenes, Salmonella Enteritidis e Escherichia coli) foi realizada pelo método de microdiluição. O efeito dos extratos aquosos sobre as células bacterianas foi avaliado por imagens de microscopia eletrônica de transmissão. A avaliação da atividade antioxidante foi determinada pelo método ABTS e DPPH. O extrato aquoso das folhas frescas apresentou maiores teores de flavonoides e atividade antioxidante por ABTS em comparação com o extrato de folhas secas. Os compostos fenólicos, taninos e a atividade antioxidante pelo método DPPH não diferiram significativamente entre ambos os tipos de folhas. Ambos os extratos aquosos apresentaram atividade antimicrobiana apenas sobre as bactérias Gram-positivas (S. aureus e L. monocytogenes). Foram observadas alterações celulares em S. aureus e L. monocytogenes sob ação do extrato aquoso de folhas frescas e secas. Os resultados indicam a possibilidade de utilização do extrato aquoso das folhas secas de C. blanchetianus como aditivo bioativo e para melhoria da segurança de alimentos, no que diz respeito às bactérias Gram-positivas.
Perfil epidemiológico da hanseníase na Bahia e no município de Teixeira de Freitas
Authors: Rocha Thiago , Pires Luanna , Santana Ana Luiza , Lima Hayana , Martins Gabriela , Silva João Batista Lopes
Published: January 2022

O objetivo deste estudo foi caracterizar o perfil epidemiológico da hanseníase no estado da Bahia e no município de Teixeira de Freitas no período de 2001 a 2019. Foram utilizados dados do Sistema de Informação de Agravos de Notificação do Ministério da Saúde e de casos notificados de Hanseníase em ambas as localidades. As variáveis analisadas foram: sexo, localidade, faixa etária, classe de operação de diagnóstico e grau de cura. É possível observar que para a Bahia, e principalmente para Teixeira de Freitas, a erradicação da doença é uma realidade pouco tangível. O estado baiano possui alta incidência de casos de hanseníase e Teixeira de Freitas apresenta incidência muito alta. Em relação às variáveis estabelecidas no estudo, tanto na Bahia quando em Teixeira de Freitas verificou-se que a predominância dos casos registrados foi do sexo masculino e da faixa etária de 30 a 39 anos.
Copper-based kesterite thin films for photoelectrochemical water splitting
Authors: Ikeda Shigeru
Published: January 2022

Copper kesterite Cu2ZnSnS4is a promising photoabsorber material for solar cells and photoelectrochemical (PEC) water splitting. In this article, we will first review the crystallographic/energetic structures of Cu2ZnSnS4in view of its applications to sunlight conversion devices. Then, historical progress in photovoltaic properties of Cu2ZnSnS4-based solar cells is introduced. Finally, studies on PEC H2evolution over Cu2ZnSnS4-based photocathodes are reviewed in detail. For realizing efficient PEC H2evolution, surface modifications with an n-type buffer layer (such as CdS) and a catalytic site (such as Pt nanoparticles) were found to be indispensable. Since these surface-modified photocathodes had poor resistances under an operating bias due to the occurrence of oxidative photocorrosion of the CdS layer and elimination of the Pt catalysts, coverage with a protection layer was required to improve the long-term durability. Moreover, partial or complete substitution of the constituent cations with some cations was proved to be effective for improving PEC properties. Although recent studies showed a rapid increase in PEC properties, there is room for further development of PEC properties by using effective combinations among surface protection(s), defect engineering(s), and band engineering(s).
On multi-step methods for singular fractional q-integro-differential equations
Authors: Hajiseyedazizi Sayyedeh Narges , Samei Mohammad Esmael , Alzabut Jehad , Chu Yu-ming
Published: January 2022

The objective of this paper is to investigate, by applying the standard Caputo fractional q-derivative of order

α

\alpha

, the existence of solutions for the singular fractional q-integro-differential equation

D

q

α

[

k

]

(

t

)

=
Ω

(

t
,

k

1

,

k

2

,

k

3

,

k

4

)

{{\mathcal{D}}}_{q}^{\alpha }\left[k]\left(t)=\Omega \left(t,{k}_{1},{k}_{2},{k}_{3},{k}_{4})

, under some boundary conditions where

Ω

\Omega

is singular at some point

0
≤
t
≤
1

0\le t\le 1

, on a time scale

T

t

0

=

{

t
:
t
=

t

0

q

n

}

∪

{

0

}

{{\mathbb{T}}}_{{t}_{0}}=\left\{t:t={t}_{0}{q}^{n}\right\}\cup \left\{0\right\}

, for

n
∈
N

n\in {\mathbb{N}}

where

t

0

∈
R

{t}_{0}\in {\mathbb{R}}

and

q
∈

(

0
,
1

)

q\in \left(0,1)

. We consider the compact map and avail the Lebesgue dominated theorem for finding solutions of the addressed problem. Besides, we prove the main results in context of completely continuous functions. Our attention is concentrated on fractional multi-step methods of both implicit and explicit type, for which sufficient existence conditions are investigated. Finally, we present some examples involving graphs, tables and algorithms to illustrate the validity of our theoretical findings.
Magnetic charged particles of optical spherical antiferromagnetic model with fractional system
Authors: Yao Shao-Wen , Korpinar Talat , Baleanu Dumitru , Korpinar Zeliha , Almohsen Bandar , Inc Mustafa
Published: January 2022

In this article, we first consider approach of optical spherical magnetic antiferromagnetic model for spherical magnetic flows of

ϒ

\Upsilon

-magnetic particle with spherical de-Sitter frame in the de-Sitter space

S

1

2

{{\mathbb{S}}}_{1}^{2}

. Hence, we establish new relationship between magnetic total phases and spherical timelike flows in de-Sitter space

S

1

2

{{\mathbb{S}}}_{1}^{2}

. In other words, the applied geometric characterization for the optical magnetic spherical antiferromagnetic spin is performed. Moreover, this approach is very useful to analyze some geometrical and physical classifications belonging to

ϒ

\Upsilon

-particle. Besides, solutions of fractional optical systems are recognized for submitted geometrical designs. Geometrical presentations for fractional solutions are obtained to interpret the model. These obtained results represent that operation is a compatible and significant application to restore optical solutions of some fractional systems. Components of models are described by physical assertions with solutions. Additionally, we get solutions of optical fractional flow equations with designs of our results in de-Sitter space

S

1

2

{{\mathbb{S}}}_{1}^{2}

.
Hermeneutik sozialer Simulationen
Authors: Dickel Sascha , Neumann Martin
Published: January 2022

Der Beitrag verbindet zwei weit auseinander liegende methodische Welten. Wir schlagen vor, das Verfahren der hermeneutischen Sequenzanalyse zur Interpretation Agentenbasierter Modellierungen zu verwenden, einer sich aktuell verbreitenden Methode sozialwissenschaftlicher Forschung. Ihr Ziel besteht in der technikgestützten Konstruktion von Szenarien, in denen spezifische soziale Konstellationen durchgespielt werden. Das konkrete Simulationsmodell, welches wir dabei exemplarisch heranziehen, bezieht sich auf Gewalteskalationen innerhalb krimineller Netzwerke. Die Simulationsresultate sind als narrative Szenarien formuliert, die hier exemplarisch einer Sequenzanalyse unterzogen werden. Damit demonstrieren wir, dass hermeneutische Sequenzanalysen zur Strukturgeneralisierung und Validierung Agentenbasierter Modelle eingesetzt werden kann. Darauf basierend schlagen wir eine digitale Hermeneutik vor, welche soziale Simulation mit der Dimension des sozialen Sinnes verbindet.
Distribution of HLA epitope frequencies in Turkish population
Authors: Oguz Fatma Savran , Oguz Suleyman Rustu , Ogret Yeliz , Karadeniz Tanju Sedat , Ciftci Hayriye Senturk , Karatas Sule , Kivanc Demet , Aydin Filiz
Published: January 2022

Objectives

The antibodies interact with the “Human Leukocyte Antigen (HLA) antigens” at specific epitopes. “Epitopes” are present on a single HLA or shared by multiple antigens. In this study, we aim to determine the frequency of prevalent epitopes common in the Turkish population.

Methods

Non-related 644 healthy volunteers were recruited, and The “HLA-A, -B, -C, -DR -DQ’s” were typed using the “Next Generation Sequencing”. The provisional and confirmed epitopes were identified using the “HLA Epitope Registry databases, HLA Epitopia Maps and Immucor Epitope databases” dated 07.02.2018. Epitope frequencies were calculated by counting the shared epitopes in the total number of shared HLA Class epitopes in our sample database.

Results

Class I HLA’s had 298 epitopes that repeated a total of 158,117 times with frequencies ranging between 0.0006 and 2.03%, and the most frequent epitope was 170RY found on 119 different alleles. Class II HLA’s had 193 epitopes that repeated a total of 93,082 times with frequencies ranging between 0.002 and 1.36%, and the most frequent epitope was 108P found on 42 different alleles.

Conclusions

Our findings summarize both the provisional, and confirmed epitope frequencies in the Turkish population and may help clinicians and immunogeneticists develop a better understanding of HLA epitope mismatches.