bluuebunny/crossref_metadata_2025 huggingface dataset:
The Immunostimulatory Potential and Resistance Aeromonas hydrophila of Pineapple Peel Extract in Nile Tilapia (Oreochromis niloticus)
Authors: Nithikulworawong Nudtha , Jiwyam Wirat
Published: July 2024

This study described the efficiency of pineapple peel extract (PPE) in increasing the immunity of Nile tilapia (Oreochromis niloticus) and in inhibiting Aeromonas hydrophila infections. The PPE concentrations used in this study were: 62.5, 125, and 250 mg/mL. 0.1 mL of PPE was administered via intraperitoneal injection into the fish. On day 7, fish was intraperitoneally injected with 0.1 mL A. hydrophila (density 108 CFU/mL). Hematology and biochemical serum parameters were observed on day 1 and 7 after injected with PPE and day 7 and 14 post-challenge with A. hydrophila. The results indicated that, red blood cells, white blood cells, and hematocrit of PPE-injected fish were significantly higher than those in the control group (p<0.05). Alkaline phosphatase, aspartate transaminase, and alanine transaminase in the fish groups receiving PPE were lower than those of the control group. After challenge test, fish injected with 125 mg/mL PPE concentration was able to significantly reduce the mortality rate compare to control (from 80.50% to 47.22%). It can be concluded that PPE was effective in preventing A. hydrophila infections, and had a positive impact on the immunity of fish. So that pineapple is an alternative plant that can be used to improve fish health.
Occurrence and prevention of incisional hernia following laparoscopic colorectal surgery
Authors: Wu Xi-Wen , Yang Ding-Quan , Wang Ming-Wei , Jiao Yan
Published: July 2024

Among minimally invasive surgical procedures, colorectal surgery is associated with a notably higher incidence of incisional hernia (IH), ranging from 1.7% to 24.3%. This complication poses a significant burden on the healthcare system annually, necessitating urgent attention from surgeons. In a study published in the World Journal of Gastrointestinal Surgery , Fan et al compared the incidence of IH among 1614 patients who underwent laparoscopic colorectal surgery with different extraction site locations and evaluated the risk factors associated with its occurrence. This editorial analyzes the current risk factors for IH after laparoscopic colorectal surgery, emphasizing the impact of obesity, surgical site infection, and the choice of incision location on its development. Furthermore, we summarize the currently available preventive measures for IH. Given the low surgical repair rate and high recurrence rate associated with IH, prevention deserves greater research and attention compared to treatment.
Diagnostic significance of serum levels of serum amyloid A, procalcitonin, and high-mobility group box 1 in identifying necrotising enterocolitis in newborns
Authors: Guo Li-Ming , Jiang Zhi-Hui , Liu Hong-Zhen , Zhang Lei
Published: July 2024

BACKGROUND

Necrotising enterocolitis (NEC) is a critical gastrointestinal emergency affecting premature and low-birth-weight neonates. Serum amyloid A (SAA), procalcitonin (PCT), and high-mobility group box 1 (HMGB1) have emerged as potential biomarkers for NEC due to their roles in inflammatory response, tissue damage, and immune regulation.

AIM

To evaluate the diagnostic value of SAA, PCT, and HMGB1 in the context of NEC in newborns.

METHODS

The study retrospectively analysed the clinical data of 48 newborns diagnosed with NEC and 50 healthy newborns admitted to the hospital. Clinical, radiological, and laboratory findings, including serum SAA, PCT, and HMGB1 Levels, were collected, and specific detection methods were used. The diagnostic value of the biomarkers was evaluated through statistical analysis, which was performed using chi-square test, t -test, correlation analysis, and receiver operating characteristic (ROC) analysis.

RESULTS

The study demonstrated significantly elevated levels of serum SAA, PCT, and HMGB1 Levels in newborns diagnosed with NEC compared with healthy controls. The correlation analysis indicated strong positive correlations among serum SAA, PCT, and HMGB1 Levels and the presence of NEC. ROC analysis revealed promising sensitivity and specificity for serum SAA, PCT, and HMGB1 Levels as potential diagnostic markers. The combined model of the three biomarkers demonstrating an extremely high area under the curve (0.908).

CONCLUSION

The diagnostic value of serum SAA, PCT, and HMGB1 Levels in NEC was highlighted. These biomarkers potentially improve the early detection, risk stratification, and clinical management of critical conditions. The findings suggest that these biomarkers may aid in timely intervention and the enhancement of outcomes for neonates affected by NEC.
Evaluation of the clinical effects of atropine in combination with remifentanil in children undergoing surgery for acute appendicitis
Authors: Li Yu-Juan , Chen Yong-Yan , Lin Xia-Lan , Zhang Wei-Zhi
Published: July 2024

BACKGROUND

Acute appendicitis (AA) is the most common cause of acute abdomen in children. Anesthesia significantly influences the surgical treatment of AA in children, making the scientific and effective selection of anesthetics crucial.

AIM

To assess the clinical effect of atropine (ATR) in combination with remifentanil (REMI) in children undergoing surgery for AA.

METHODS

In total, 108 cases of pediatric AA treated between May 2020 and May 2023 were selected, 58 of which received ATR + REMI [research group (RG)] and 50 who received REMI [control group (CG)]. Comparative analyses were conducted on the time to loss of eyelash reflex, pain resolution time, recovery time from anesthesia, incidence of adverse events (AEs; respiratory depression, hypoxemia, bradycardia, nausea and vomiting, and hypotension), intraoperative responses (head shaking, limb activity, orientation recovery, safe departure time from the operating room), hemodynamic parameters [oxygen saturation (SPO2), mean arterial pressure, heart rate, and respiratory rate], postoperative sedation score (Ramsay score), and pain level [the Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale].

RESULTS

Compared with the CG, the RG showed significantly shorter time to loss of eyelash reflex, pain resolution, recovery from anesthesia, and safe departure from the operating room. Furthermore, the incidence rates of overall AEs (head shaking, limb activity, etc. ) were lower, and influences on intraoperative hemodynamic parameters and stress response indexes were fewer. The Ramsay score at 30 min after extubation and the FLACC score at 60 min after extubation were significantly lower in the RG than in the CG.

CONCLUSION

ATR + REMI is superior to REMI alone in children undergoing AA surgery, with a lower incidence of AEs, fewer influences on hemodynamics and stress responses, and better post-anesthesia recovery.
Effectiveness of magnetic resonance imaging and spiral computed tomography in the staging and treatment prognosis of colorectal cancer
Authors: Bai Lu-Na , Zhang Lu-Xian
Published: July 2024

BACKGROUND

Colorectal cancer (CRC) is a prevalent cancer type in clinical settings; its early signs can be difficult to detect, which often results in late-stage diagnoses in many patients. The early detection and diagnosis of CRC are crucial for improving treatment success and patient survival rates. Recently, imaging techniques have been hypothesized to be essential in managing CRC, with magnetic resonance imaging (MRI) and spiral computed tomography (SCT) playing a significant role in enhancing diagnostic and treatment approaches.

AIM

To explore the effectiveness of MRI and SCT in the preoperative staging of CRC and the prognosis of laparoscopic treatment.

METHODS

Ninety-five individuals admitted to Zhongshan Hospital Xiamen University underwent MRI and SCT and were diagnosed with CRC. The precision of MRI and SCT for the presurgical classification of CRC was assessed, and pathological staging was used as a reference. Receiver operating characteristic curves were used to evaluate the diagnostic efficacy of blood volume, blood flow, time to peak, permeability surface, blood reflux constant, volume transfer constant, and extracellular extravascular space volume fraction on the prognosis of patients with CRC.

RESULTS

Pathological biopsies confirmed the following CRC stages: 23, 23, 32, and 17 at T1, T2, T3, and T4, respectively. There were 39 cases at the N0 stage, 22 at N1, 34 at N2, 44 at M0 stage, and 51 at M1. Using pathological findings as the benchmark, the combined use of MRI and SCT for preoperative TNM staging in patients with CRC demonstrated superior sensitivity, specificity, and accuracy compared with either modality alone, with a statistically significant difference in accuracy (P < 0.05). Receiver operating characteristic curve analysis revealed the predictive values for laparoscopic treatment prognosis, as indicated by the areas under the curve for blood volume, blood flow, time to peak, and permeability surface, blood reflux constant, volume transfer constant, and extracellular extravascular space volume fraction were 0.750, 0.683, 0.772, 0.761, 0.709, 0.719, and 0.910, respectively. The corresponding sensitivity and specificity values were also obtained (P < 0.05).

CONCLUSION

MRI with SCT is effective in the clinical diagnosis of patients with CRC and is worthy of clinical promotion.
Correlation between abdominal computed tomography signs and postoperative prognosis for patients with colorectal cancer
Authors: Yang Shao-Min , Liu Jie-Mei , Wen Rui-Ping , Qian Yu-Dong , He Jing-Bo , Sun Jing-Song
Published: July 2024

BACKGROUND

Patients with different stages of colorectal cancer (CRC) exhibit different abdominal computed tomography (CT) signs. Therefore, the influence of CT signs on CRC prognosis must be determined.

AIM

To observe abdominal CT signs in patients with CRC and analyze the correlation between the CT signs and postoperative prognosis.

METHODS

The clinical history and CT imaging results of 88 patients with CRC who underwent radical surgery at Xingtan Hospital Affiliated to Shunde Hospital of Southern Medical University were retrospectively analyzed. Univariate and multivariate Cox regression analyses were used to explore the independent risk factors for postoperative death in patients with CRC. The three-year survival rate was analyzed using the Kaplan-Meier curve, and the correlation between postoperative survival time and abdominal CT signs in patients with CRC was analyzed using Spearman correlation analysis.

RESULTS

For patients with CRC, the three-year survival rate was 73.86%. The death group exhibited more severe characteristics than the survival group. A multivariate Cox regression model analysis showed that body mass index (BMI), degree of periintestinal infiltration, tumor size, and lymph node CT value were independent factors influencing postoperative death (P < 0.05 for all). Patients with characteristics typical to the death group had a low three-year survival rate (log-rank χ 2 = 66.487, 11.346, 12.500, and 27.672, respectively, P < 0.05 for all). The survival time of CRC patients was negatively correlated with BMI, degree of periintestinal infiltration, tumor size, lymph node CT value, mean tumor long-axis diameter, and mean tumor short-axis diameter (r = -0.559, 0.679, -0.430, -0.585, -0.425, and -0.385, respectively, P < 0.05 for all). BMI was positively correlated with the degree of periintestinal invasion, lymph node CT value, and mean tumor short-axis diameter (r = 0.303, 0.431, and 0.437, respectively, P < 0.05 for all).

CONCLUSION

The degree of periintestinal infiltration, tumor size, and lymph node CT value are crucial for evaluating the prognosis of patients with CRC.
“Hepatic hilum area priority, liver posterior first”: An optimized strategy in laparoscopic resection for type III-IV hilar cholangiocarcinoma
Authors: Hu Xiao-Si , Wang Yong , Pan Hong-Tao , Zhu Chao , Chen Shi-Lei , Zhou Shuai , Liu Hui-Chun , Pang Qing , Jin Hao
Published: July 2024

BACKGROUND

In recent years, pure laparoscopic radical surgery for Bismuth-Corlette type III and IV hilar cholangiocarcinoma (HCCA) has been preliminarily explored and applied, but the surgical strategy and safety are still worthy of further improvement and attention.

AIM

To summarize and share the application experience of the emerging strategy of “hepatic hilum area dissection priority, liver posterior separation first” in pure laparoscopic radical resection for patients with HCCA of Bismuth-Corlette types III and IV.

METHODS

The clinical data and surgical videos of 6 patients with HCCA of Bismuth-Corlette types III and IV who underwent pure laparoscopic radical resection in our department from December 2021 to December 2023 were retrospectively analyzed.

RESULTS

Among the 6 patients, 4 were males and 2 were females. The average age was 62.2 ± 11.0 years, and the median body mass index was 20.7 (19.2-24.1) kg/m2. The preoperative median total bilirubin was 57.7 (16.0-155.7) μmol/L. One patient had Bismuth-Corlette type IIIa, 4 patients had Bismuth-Corlette type IIIb, and 1 patient had Bismuth-Corlette type IV. All patients successfully underwent pure laparoscopic radical resection following the strategy of “hepatic hilum area dissection priority, liver posterior separation first”. The operation time was 358.3 ± 85.0 minutes, and the intraoperative blood loss volume was 195.0 ± 108.4 mL. None of the patients received blood transfusions during the perioperative period. The median length of stay was 8.3 (7.0-10.0) days. Mild bile leakage occurred in 2 patients, and all patients were discharged without serious surgery-related complications.

CONCLUSION

The emerging strategy of “hepatic hilum area dissection priority, liver posterior separation first” is safe and feasible in pure laparoscopic radical surgery for patients with HCCA of Bismuth-Corlette types III and IV. This strategy is helpful for promoting the modularization and process of pure laparoscopic radical surgery for complicated HCCA, shortens the learning curve, and is worthy of further clinical application.
Yangyin Huowei mixture alleviates chronic atrophic gastritis by inhibiting the IL-10/JAK1/STAT3 pathway
Authors: Xie Shan-Shan , Zhi Yong , Shao Chang-Ming , Zeng Bin-Fang
Published: July 2024

BACKGROUND

The Chinese medicine Yangyin Huowei mixture (YYHWM) exhibits good clinical efficacy in the treatment of chronic atrophic gastritis (CAG), but the mechanisms underlying its activity remain unclear.

AIM

To investigate the therapeutic effects of YYHWM and its underlying mechanisms in a CAG rat model.

METHODS

Sprague-Dawley rats were allocated into control, model, vitacoenzyme, and low, medium, and high-dose YYHWM groups. CAG was induced in rats using N-methyl-N′-nitro-N-nitrosoguanidine, ranitidine hydrochloride, hunger and satiety perturbation, and ethanol gavage. Following an 8-wk intervention period, stomach samples were taken, stained, and examined for histopathological changes. ELISA was utilized to quantify serum levels of PG-I, PG-II, G-17, IL-1β, IL-6, and TNF-α. Western blot analysis was performed to evaluate protein expression of IL-10, JAK1, and STAT3.

RESULTS

The model group showed gastric mucosal layer disruption and inflammatory cell infiltration. Compared with the blank control group, serum levels of PGI, PGII, and G-17 in the model group were significantly reduced (82.41 ± 3.53 vs 38.52 ± 1.71, 23.06 ± 0.96 vs 11.06 ± 0.70, and 493.09 ± 12.17 vs 225.52 ± 17.44, P < 0.01 for all), whereas those of IL-1β, IL-6, and TNF-α were significantly increased (30.15 ± 3.07 vs 80.98 ± 4.47, 69.05 ± 12.72 vs 110.85 ± 6.68, and 209.24 ± 11.62 vs 313.37 ± 36.77, P < 0.01 for all), and the protein levels of IL-10, JAK1, and STAT3 were higher in gastric mucosal tissues (0.47 ± 0.10 vs 1.11 ± 0.09, 0.49 ± 0.05 vs 0.99 ± 0.07, and 0.24 ± 0.05 vs 1.04 ± 0.14, P < 0.01 for all). Compared with the model group, high-dose YYHWM treatment significantly improved the gastric mucosal tissue damage, increased the levels of PGI, PGII, and G-17 (38.52 ± 1.71 vs 50.41 ± 3.53, 11.06 ± 0.70 vs 15.33 ± 1.24, and 225.52 ± 17.44 vs 329.22 ± 29.11, P < 0.01 for all), decreased the levels of IL-1β, IL-6, and TNF-α (80.98 ± 4.47 vs 61.56 ± 4.02, 110.85 ± 6.68 vs 89.20 ± 8.48, and 313.37 ± 36.77 vs 267.30 ± 9.31, P < 0.01 for all), and evidently decreased the protein levels of IL-10 and STAT3 in gastric mucosal tissues (1.11 ± 0.09 vs 0.19 ± 0.07 and 1.04 ± 0.14 vs 0.55 ± 0.09, P < 0.01 for both).

CONCLUSION

YYHWM reduces the release of inflammatory factors by inhibiting the IL-10/JAK1/STAT3 pathway, alleviating gastric mucosal damage, and enhancing gastric secretory function, thereby ameliorating CAG development and cancer transformation.
Sequential bowel necrosis and large gastric ulcer in a patient with a ruptured femoral artery: A case report
Authors: Wang Peng , Wang Ting-Gang , Yu An-Yong
Published: July 2024

BACKGROUND

Severe bleeding as a result of a major vascular injury is a potentially fatal event commonly observed in the emergency department. Bowel necrosis and gastric ulcers secondary to ischemia are rare due to their rich blood supply. In this case, we present the case of a patient who was treated successfully following rupture of his femoral artery resulting in bowel necrosis and an unusually large gastric ulcer.

CASE SUMMARY

A 28-year-old male patient sustained a knife stab wound to the right thigh, causing rupture of his femoral artery and leading to massive bleeding. He underwent cardiopulmonary resuscitation and received a large blood transfusion. Abdominal surgeries confirmed bowel necrosis, and jejunostomy was performed. The necrotic intestine was removed, the remaining intestine was anastomosed, and the right thigh was amputated. After three surgeries, the patient's overall condition gradually improved, and the patient was discharged from the hospital. However, one day after discharge, the patient was admitted again due to dizziness and melena, and a gastroduodenoscopy revealed a giant banded ulcer. After 2 weeks of treatment, the ulcer had decreased in size without bleeding. Six months after the last surgery, enterostomy and reintroduction surgery were completed. The patient was fitted with a right lower limb prosthesis one year after surgery. After 3 years of follow-up, the patient did not complain of discomfort.

CONCLUSION

Trauma department physicians need to be aware of the possible serious complications involving the abdomen of trauma patients with massive bleeding.
Misdiagnosis of hemangioma of left triangular ligament of the liver as gastric submucosal stromal tumor: Two case reports
Authors: Wang Jing-Jie , Zhang Fen-Ming , Chen Wei , Zhu Hua-Tuo , Gui Ning-Long , Li Ai-Qing , Chen Hong-Tan
Published: July 2024

BACKGROUND

Extragastric lesions are typically not misdiagnosed as gastric submucosal tumor (SMT). However, we encountered two rare cases where extrinsic lesions were misdiagnosed as gastric SMTs.

CASE SUMMARY

We describe two cases of gastric SMT-like protrusions initially misdiagnosed as gastric SMTs by the abdominal contrast-enhanced computed tomography (CT) and endoscopic ultrasound (EUS). Based on the CT and EUS findings, the patients underwent gastroscopy; however, no tumor was identified after incising the gastric wall. Subsequent surgical exploration revealed no gastric lesions in both patients, but a mass was found in the left triangular ligament of the liver. The patients underwent laparoscopic tumor resection, and the postoperative diagnosis was hepatic hemangiomas.

CONCLUSION

During EUS procedures, scanning across different layers and at varying degrees of gastric cavity distension, coupled with meticulous image analysis, has the potential to mitigate the likelihood of such misdiagnoses.
Prioritizing Mental Well-being in Emerging Educational Models: Strategies for Integrating Social and Emotional Learning (SEL) to Support Student Mental Health
Authors: Jayatissa Dimani
Published: July 2024

This paper conducts a comprehensive review of the effectiveness of integrating Social and Emotional Learning (SEL) practices into emerging educational models to support student mental well-being, with a particular focus on Canadian contexts. Employing a systematic literature review methodology, the study utilized Google Scholar as the primary database, filtering results based on inclusion and exclusion criteria, emphasizing relevance, quality, and recency. The main findings underscore a research gap between acknowledgment of the importance of SEL, and its implementation in Canadian schools. Strategies for integrating SEL into educational settings are reviewed, highlighting ongoing initiatives of British Columbia aimed at advancing SEL within teacher training programs and educational policies. The study also highlights escalating concerns regarding the mental health of Canadian children and youth, impaired by the COVID-19 pandemic. Implications for educational policy and practice, including promoting systematic assessment of students’ social-emotional skills and ensuring the appropriate developmental delivery of SEL through content, are emphasized as key considerations for educational policymakers and practitioners. The paper concludes that a holistic approach is advocated for fostering Canadian children and youth's social-emotional skills, crucial for their well-being and success in educational settings.
Performing 1-1 Interventions to Address Mathematics Anxiety – An Intervention Case Study of 3 Brazilian Women Who Believed They Were Stupid in Mathematics
Authors: Alves Karina Lumena , Pará Telma , Johnston-Wilder Sue , Baker Janet
Published: July 2024

Mathematics Anxiety is well-researched, but solutions are few. This study shows the potential to provide an affordable solution, one that could ultimately be rolled out across the country and the world. The 1:1 interventions involve inviting the participants to tell their math story and then introducing the Mathematical Resilience Framework and reframing adverse prior experiences as unrelated to intrinsic ability. The framework includes three tools: the hand model of the brain, the growth zone model, and the relaxation response. The intervention participants were Brazilian volunteers living in England from the local and virtual communities. The levels of Mathematics Anxiety were measured before the intervention using the Betz (1978) scale, and narrative records were made. The qualitative data were analyzed using deductive thematic analysis (Braun Clarke, 2006) through the lens of the Mathematical Resilience Framework. The data indicated the positive impact of performing this kind of intervention.
The Importance of International Students in the United States
Authors: Okai Lawrencia Baaba , Mandayam Gokul
Published: July 2024

The overarching focus of this study is to gain a comprehensive understanding of how the admission of international students into institutions of higher education in the US, creates advantages to their college campuses and communities, apart from its concomitant liabilities. The US has been the most preferred study abroad destination for international students (IIE, Open Doors, 2023). In the 2022/2023 academic year, 1,057,188 international students enrolled in colleges and universities in the US representing about 25% of total international students enrollment worldwide (Bound et al., 2020).This study will be an exploratory attempt to understand the advantages that international students bring to higher education institutions in the US and their contributions to the country's economy overall. It is intended to provide a rich description of international students contributions over the years, in addition to the costs and benefits associated with admission of international students.
Enhancing Critical Thinking Skills in Geometry through the Guided Discovery Approach with GeoGebra
Authors: Verallo Elmer R. , Cajandig Allan Jay S.
Published: July 2024

In this modern era of K-12 curriculum, if students are expected to be knowledgeable and skilled, it is a requirement for the teachers to meet and cope with the necessary skills and competencies for the students to be more competent. This study is developed to investigate the effect of the Guided Discovery Approach (GDA) with GeoGebra on critical thinking skills in ninth-grade geometry students at Baluan National High School during the 2022-2023. Employing a true experimental research design, the study revealed that the student’s level of achievement in critical thinking skills in creating, applying, analyzing, and evaluating both in the conventional and experimental groups increases in mean gain scores of 28.27 and 32.8 respectively. The t-test result further shows a t(28) = 2.70 and a p-value = 0.01 indicating that the GDA with GeoGebra in teaching Geometry significantly improved students' critical thinking. It further reveals a significant increase in post-test scores for the experimental group emphasizing the effectiveness of GDA with GeoGebra. While students moderately accepted GeoGebra, there is no significant relationship between their critical thinking skills and acceptability. The findings underscore the importance of instructional methods in improving critical thinking skills, showcasing the potential of GDA with GeoGebra in Geometry.
Reshaping Mathematics Instruction Via Impact of AI Chatbots on Secondary Education Pre-service Teachers
Authors: Luzano Jay Fie P.
Published: July 2024

This study assessed the level of impact of AI Chatbots (ChatGPT, Gemini, and Perplexity) in Mathematics Education. The study employed a descriptive research design where structured survey questionnaires were used and administered to ninety (90) Secondary Education Pre-service Teachers at Bukidnon State University, Philippines. Results showed that the level of impact of the AI Chatbots (ChatGPT, Gemini, and Perplexity) in Mathematics Education on the nine (9) factors is Very High, namely; (1) Effectiveness ; (2) Engagement ; (3) Accessibility ; (4) Personalization ; (5) Feedback Quality ; (6) Confidence Building ; (7) Time Efficiency ; (8) Adaptability ; and (9) Student Satisfaction . The findings demonstrate a positive student assessment on AI chatbots (ChatGPT, Gemini, and Perplexity) in mathematics education, consistently rated highly across various factors, indicating their significant impact on reshaping instruction, providing valuable support, enhancing learning experiences, and boosting confidence and proficiency in math, underscoring the transformative potential of AI technology and its essential integration into educational practices to address students' evolving needs in the digital age.
An Experiential Journey: A Year of a Professor Using AI in the Classroom and Research
Authors: Mulally Tif
Published: July 2024

This paper explores the integration of artificial intelligence (AI) in education and research, highlighting its potential to transform traditional teaching methods and enhance academic inquiry. The use of AI in education is examined, focusing on its ability to streamline administrative tasks, provide personalized instruction, and support teacher professional development. The benefits and challenges of AI adoption in the classroom are discussed, including its impact on teacher burnout and the potential disruption of teacher-student relationships. Additionally, the paper explores the applications of AI in scientific research, emphasizing its role in data analysis, literature review, predictive modeling, and collaborative research. The experiences of a professor who integrated AI into their classroom are shared, and the decision-making process, adjustments made, and the importance of balancing AI-driven instruction with interactive in-class activities are discussed. The paper highlights the need for ongoing evaluation, adaptation, and human-AI collaboration to ensure AI's responsible and effective integration in education and research.
THE IMPACT OF THE COVID PANDEMIC ON THE BUSINESS ENVIRONMENT OF GEORGIA AND THE STRATEGIES TO FIGHT AGAINST THE PANDEMIC
Authors: Kvachantiradze Besik
Published: July 2024

Besik Kvachantiradze
E-mail: b.kvatchantiradze@gmail.com
PhD Students,Batumi Shota Rustaveli state University
Batumi, Georgia
https://orcid.org/0000-0003-2833-1007
 
Abstract: The COVID-19 pandemic has significantly changed the business landscape around the whole world. Georgia was no exception. Against the challenges caused by the COVID-19 pandemic, the business environment of Georgia has undergone significant transformations. The country has recognized the vital role of economic development in the well-being of society, and the government has focused on promoting the growth of innovation while overcoming the obstacles caused by the pandemic. The COVID-19 pandemic has disrupted global trade and tourism, which has had a huge impact on Georgia's economy. With a heavy reliance on tourism, border closures and travel restrictions have led to a sharp drop in tourist arrivals, leading to job losses and reduced business revenue. Small and medium enterprises (SMEs), which are the backbone of Georgia's economy, have faced enormous challenges during the pandemic. Many businesses, particularly in the retail, hospitality and entertainment sectors, have been forced to close due to financial constraints and lack of government support. Addressing these obstacles required coordinated efforts by government authorities and international organizations to mitigate the negative effects of the pandemic and implement recovery efforts. Georgia has been trying to adapt to global economic trends for years;  and the pandemic has highlighted the need for acceleration of innovation and adaptation to international business norms and standards.
Keywords: Business environment, small and medium business
JEL classification: O1, G2, E4
PARTNERSHIP RELATIONS AND THE FEELING OF SUBJECTIVE WELL-BEING
Authors: Katamadze Davit , Beridze Ketevan , Rusieshvili Nino , Vekua Lizi
Published: July 2024

Davit Katamadze
E-mail: datoqatamadze@gmail.com
Assistant Professor of Batumi Shota Rustaveli State University
Georgia, Batumi
https://orcid.org/0009-0008-8815-1167
 
Ketevan Beridze
E-mail: k.beridze@bsu.edu.ge
Professor of Batumi Shota Rustaveli State University
Georgia, Batumi
https://orcid.org/0000-0001-6268-7037
 
Nino Rusieshvili
E-mail: niniarusieshvili@gmail.com
Teacher, Master of Clinical Psychology, BSU, special teacher of psychology clinic
Georgia, Batumi
https://orcid.org/0009-0002-6370-5553
 
Lizi Vekua
E-mail: vekualiza10@gmail.com
Batumi Shota Rustaveli State University, Third year student of psychology
Georgia, Batumi
https://orcid.org/0009-0004-2193-2779
 
Abstract. A person's life satisfaction is determined by various factors: feeling satisfied with oneself and achievements, positive relationships, social involvement, independence, self-acceptance, continuous growth. Our well-being is also greatly influenced by partnership relations.
As part of our research, I wanted to find out how much our love relationships govern our sense of subjective well-being. An unhealthy relationship can affect many areas of mental health, life satisfaction, self-perception, and even self-esteem.
A positive partner relationship, characterized by factors such as emotional support, friendship, intimacy, and effective communication, is associated with reduced stress levels, improved mood, and greater psychological resilience (Pietromonaco & Collins, 2017). Moreover, the benefits of healthy partnerships go beyond psychological well-being to include aspects of physical health. For example, individuals with satisfying relationships have lower rates of cardiovascular disease, better immune system function, and even longer life spans (Robles & Kiecolt-Glaser, 2003).
Having a supportive partner can also enhance individuals' social well-being by providing belonging, validation, and social support during difficult times (Gable & Gosnell, 2013).
It is interesting to believe that two people can have such a great influence on each other, that their symbiosis can lead not only to their relationship satisfaction and happiness, but also to the level of well-being, self-acceptance, autonomy, adaptation to the environment, etc. These factors will be discussed in the paper.
Romantic relationships are a central aspect of most people's lives. We hypothesize that satisfaction with the partnership affects subjective well-being and life satisfaction.
 
Key words: partnership relations, well-being, satisfaction, partner.
 
JEL classification: Y800
ANALYSIS OF COUNTRIES' IMAGE FROM THE PERSPECTIVE OF THEIR CONSUMERS: THE IMPACT OF POLITICAL, ECONOMIC, AND TECHNO-SOCIO-CULTURAL DESIRE
Authors: Monteiro Thel , Maganin Henrique , Fantin Sandra , Larios -Gomez Emígido , Otero Mónica
Published: July 2024

Thel Monteiro
E-mail: thel.monteiro@puc-campinas.edu.br
Doctor, Pontifícia Universidade Católica de Campinas
Campinas, Brazil
https://orcid.org/0000-0002-0290-1676
 
Henrique Maganin
E-mail: henriquemaganin@gmail.com
Bachelor, Universidade Metodista de Piracicaba
Piracicaba, Brazil
https://orcid.org/0009-0000-4672-0116
 
Sandra Fantin
E-mail: sandra.fantin@puc-campinas.edu.br
Master, Pontifícia Universidade Católica de Campinas
Campinas, Brazil
https://orcid.org/0000-0002-0975-8876
 
Emígido Larios -Gomez
E-mail: herr.larios@gmail.com
Benemérita Universidade Autônoma de Puebla
Puebla, Mexico
https://orcid.org/0000-0002-3514-1319
 
Mónica Otero
E-mail: monica.penalosa@utadeo.edu.co
Master, Universidade de Bogotá
Bogota, Colombia
https://orcid.org/0000-0002-2208-9224
 
Abstract: This study aims to deepen the understanding of marketing and the development of its strategies, with a particular focus on marketing mix management. It seeks to identify consumer perceptions from three Latin American countries regarding their national images, considering the impact of political, economic, and techno-social factors. The project employs an exploratory study design, utilizing both primary and secondary data, bibliographic research, and descriptive statistics through the country image scale developed by Martin and Eroglu (1993). According to these authors, country image is defined as the totality of all descriptive, inferential, and informative beliefs about a particular country. The study highlights the implications of utilizing marketing strategies based on these evaluations and perceptions, emphasizing the necessity of constructing a trustworthy image for consumers in the execution of goods or services.
 
Keywords: Marketing strategy, Country image, retail.
JEL classification: M30
A formação socioespacial para melhor compreender o continente africano: notas e exemplos
Authors: Carluccio de Andrade Vinícius
Published: July 2024

Este trabalho almeja contribuir para a compreensão das particularidades das formações socioespaciais que compõem o continente africano. Para isso, o ponto de partida é a ciência geográfica. Admite-se, portanto, que há um vácuo em estudos acerca dos territórios africanos na Geografia - uma lacuna, que por si só, é política. Destarte, com base na elaboração de formação socioespacial, é possível enfrentar as visões generalistas e generalizantes que normalmente relacionam-se à África. A África não é uma unidade política, mas um continente com 54 territórios distintos. As especificidades não podem ser ignoradas; embora existam pontos de convergência, as diferenças se fazem presentes. Assim, a partir de casos - tal qual o colonialismo, o afro-pessimismo e o afro-otimismo -, busca-se vencer a generalização. Para distinguir características próprias de cada formação socioespacial, foram utilizadas fontes secundárias. A comparação fez-se imperiosa para encontrar convergências e divergências relativas aos países que compõem a África. Com isso, embora a maioria das formações socioespaciais, por exemplo, tenham sofrido com o colonialismo, o próprio processo colonizatório e seu fim foram díspares em cada território. O mesmo ocorre com o afro-pessimismo e o afro-otimismo: o agrupamento abstrato desconsidera exceções.
PENGARUH MEDIA PEMBELAJARAN ICT BERBASIS CLASSROOM DAN QUIZIZ TERHADAP MINAT BELAJAR SISWA PADA MATERI STATISTIKA
Authors: Deni Andika Nur Pratama  , Loviga Denny Pratama
Published: July 2024

This research aims to examine the influence of classroom-based ICT learning media on students' interest in learning in statistics material for class VIII B at MTs SA Tarbiyatus Shibyan Guyangan Krucil Probolinggo. The approach applied in this research is a case study using quantitative methods. Data collection was carried out through observation, interviews, questionnaires, tests, and documentation. The researchers' findings identified that the results of the research that had been carried out showed that in terms of the influence of classroom and quiziz-based ICT learning media on students' interest in learning mathematics taken by research subjects with a total of 20 students in one class VIII B at MTs SA Tarbiyatus Shibyan with results obtained sig < α (0.001 < 0.05) then H0 is rejected, the regression line equation is accepted or the variable is the influence of classroom-based ICT learning media (X1) and quizzes (X2) on interest in learning (Y). And getting Fhit = 10.929 > Ftab = 3.592 then H0 is rejected, the regression line equation is accepted or the variables X1 (Classroom Based ICT Learning Media) and And for the residual data normality test, it is found that sig > α (0.116 > 0.05) then H0 is rejected, there is a difference between the residual data and normal data, D_count= 0.215 <〖 D〗_tabel= 0.29407 (5%) then H0 is accepted , there is no difference between residual data and normal data. So in this research developing ICT-based learning media based on Classroom and Quiz really influences students' interest in learning mathematics.
IMPLEMENTATION OF DEEP NEURAL NETWORKS (DNN) FOR PAVEMENT CRACK DETECTION
Authors:   University of Belgrade, Faculty of Civil Engineering, Serbia, Lukić Miloš , Gavran Dejan ,   University of Belgrade, Faculty of Civil Engineering, Serbia, Fric Sanja ,   University of Belgrade, Faculty of Civil Engineering, Serbia, Ilić Vladan ,   University of Belgrade, Faculty of Civil Engineering, Serbia, Trpčevski Filip ,   University of Belgrade, Faculty of Civil Engineering, Serbia, Vranjevac Stefan ,   University of Belgrade, Faculty of Civil Engineering, Serbia, Milovanović Nikola ,   University of Belgrade, Faculty of Civil Engineering, Serbia
Published: July 2024

The lifespan of a structure encompasses its initial construction, followed by its operational phase, and ultimately, its rehabilitation. To accurately determine the optimal timing for rehabilitation, it is essential to continuously monitor the current state of the structure. Applied to road infrastructure, this monitoring process entails the systematic collection of data on pavement damage. This paper provides an analysis of existing models for detecting pavement cracks and introduces a detection method leveraging artificial intelligence techniques, specifically deep neural networks, and transfer learning. During the selection process, various deep neural network architectures, including ResNET 50 and ResNET 34, were evaluated. Comparative analysis revealed that the ResNET 50 network achieved the highest accuracy (Acc) in crack detection
ANALYSIS OF REASONS FOR INSTABILITY ON CUT-SLOPES AND REMEDIATION MEASURES
Authors: Izeiroski Rustem , Zafirovski Zlatko ,   Ss. Cyril and Methodius University, Faculty of Civil Engineering, North Macedonia
Published: July 2024

Safety of the road is a key factor for undisturbed and fast flow of traffic. Especially, when it comes to motorways which represent the highest rank of road with highest flow of vehicles, the safety in every sense of the word must be satisfied. However, the motorways, aside from the fact that they need to fulfill all the requirements for uninterrupted flow and appropriate speed, they also need to satisfy the safety requirements. One of the safety requirements which must be fulfilled is that the cut slopes must be respectively secured, so there wouldn’t be any problems with rockfalls and landslides. For that reason, a detailed geological features analysis is required, as well as hydrological and seismic conditions of the region. On this paper, a similar example will be analyzed, on the section of the trans-European corridor 8, Kicevo – Ohrid, it will be analyzed one cut slope with its geological features, the problem that were noticed on the field while doing the construction works, stability analysis of the slope, as well as the methods used for remediation and stabilization of the slope.
Rancang Bangun Sistem Informasi Katering Berbasis Web Menggunakan Code Igniter
Authors: Yaowita Irvan , Budi Akhmad
Published: July 2024

One of the basic human needs is food for consumption. The food consumed can be divided into 2 types, firstly is food that must be cooked and secondly is food that can be consumed directly without cooking. Families can get cooked food by cooking the desired food themselves. Apart from that, cooked food can also be obtained by buying food in canteens, cafetaria, restaurants or catering. Food obtained from canteens, cafetaria and restaurants is generally obtained by purchasing directly on site. Meanwhile, food obtained from catering is generally obtained by ordering a menu from the catering business. The ordered menu can be a single menu or a package menu. Mentari Catering aims to optimize the use of information technology so that customers have the freedom to order the food offered. The aim of this research is to build a web site-based information system to manage orders from Mentari catering customers. The system development method used in this research is the waterfall model. In this research too, CodeIgniter is used to create web applications quickly and easily. The result of this research is a website-based system to make it easier for catering customers to order both package menus and single menus. Apart from that, customers can also provide testimonials about the food menu and services provided. Testimonials can be a consideration for potential customers who want to order.
Hipertensão intra-abdominal /síndrome compartimental abdominal em pacientes com COVID-19: uma revisão integrativa
Authors: Bueno Sabryna Castro Bernardes , Farias João Pedro de Oliveira , Nunes Pedro Morais
Published: July 2024

Introdução: Lesões subepiteliais são protuberâncias do trato digestivo cobertas por mucosa normal. Embora sejam achados incidentais frequentemente benignos em endoscopias digestivas, algumas lesões apresentam potencial maligno. A ultrassonografia endoscópica caracteriza melhor estas lesões através da avaliação detalhada das camadas da parede do órgão, além da relação com órgãos vizinhos. Materiais e Métodos: Para a elaboração deste artigo de revisão foram consultados artigos científicos e artigos de revisão publicados e referenciados na Medline/PubMED, SciELO e Cochrane entre 2000 e 2024. Resultados e Discussão: A ultrassonografia endoscópica é o método de imagem com maior acurácia no diagnóstico da camada da parede gástrica comprometida por lesões ou massas, além de estudar a ecogenicidade da lesão, o que ajuda no diagnóstico diferencial. Apesar disso, a dúvida diagnóstica permanece em muitas lesões, sendo necessário estudos adicionais citológicos/histológicos. Considerações Finais: A ecoendoscopia é um método seguro e detalhado sendo considerado o melhor exame de imagem para avaliação de lesões subepiteliais do trato digestório. As técnicas endoscópicas de ressecção têm sido utilizadas de forma crescente. A cirurgia é um método de excisão particularmente útil em lesões de camadas profundas e/ou de grandes dimensões.
Bezoar de madeira em trato gastrointestinal: relato de caso e revisão da literatura
Authors: Arrieta Julio Cesar Denis Ricaldi , Mendonça Arthur Sodré de , Alexandrino Larissa Prezotto , Almeida Antônio Carlos Oliveira de , Miri Tadeu Junior
Published: July 2024

Introdução: Bezoares são concreções de materiais ingeridos que se acumulam no trato gastrointestinal, causando obstruções e outras complicações clínicas. Entre os vários tipos de bezoares, os de madeira são extremamente raros, com poucos casos documentados na literatura médica. A etiologia dos bezoares inclui a ingestão de substâncias indigeríveis, distúrbios de motilidade gastrointestinal e condições predisponentes, como cirurgias prévias ou doenças metabólicas. Metodologia: Foi realizada uma busca em bases de dados médicas como PubMed, SciELO e Cochrane, utilizando os termos "bezoar do trato gastrointestinal", "madeira" e "diagnóstico". Foram selecionados artigos publicados entre 2004 e junho de 2024. Resultados: Bezoares podem ser assintomáticos ou causar sintomas como dor abdominal, náuseas, vômitos e obstrução intestinal. O diagnóstico é geralmente feito por endoscopia digestiva alta, ultrassonografia ou estudos radiológicos contrastados. O tratamento inclui a remoção endoscópica ou cirúrgica do bezoar, dependendo do tamanho e das complicações associadas. Conclusão: Bezoares de madeira, embora raros e geralmente assintomáticos, devem ser considerados no diagnóstico diferencial de obstruções intestinais. O diagnóstico precoce e o manejo adequado são cruciais para prevenir complicações graves e melhorar os desfechos clínicos dos pacientes.
Prosedur Perizinan UMKM sebagai Inti-Plasma pada Usaha Besar
Authors: Ardiansyah Muhammad Miqdad , Purwaningsih Sri Budi
Published: July 2024

Penelitian ini mengeksplorasi prosedur perizinan hukum untuk penggunaan lahan oleh Usaha Mikro, Kecil, dan Menengah (UMKM) dalam kerangka inti-plasma oleh perusahaan besar, yang penting untuk mendukung pertumbuhan ekonomi berkelanjutan. Mengakui UMKM sebagai komponen penting dalam rantai pasokan perusahaan besar, penelitian ini mengisi kesenjangan pengetahuan dengan menjelaskan aspek prosedural dan statuter dari perizinan penggunaan lahan UMKM berdasarkan Pasal 27, yang mengharuskan dukungan perusahaan besar dalam penyediaan lahan untuk UMKM. Dengan menggunakan metode yuridis normatif dan pendekatan statuter, studi ini mengungkapkan bahwa perusahaan besar memfasilitasi integrasi UMKM dengan menyediakan area depan supermarket untuk disewa. Temuan menunjukkan perlunya pedoman regulasi yang lebih jelas untuk meningkatkan partisipasi dan dukungan UMKM, sehingga berdampak pada strategi pengembangan ekonomi.