bluuebunny/crossref_metadata_2025 huggingface dataset:
Serotonin 2C Antagonism in the Lateral Orbitofrontal Cortex Ameliorates Cue-Enhanced Risk Preference and Restores Sensitivity to Reinforcer Devaluation in Male Rats
Authors: Hathaway Brett A. , Schumacher Jackson D. , Hrelja Kelly M. , Winstanley Catharine A.
Published: November 2021

Previous research has indicated that reward-paired cues can enhance disadvantageous risky choice in both humans and rodents. Systemic administration of a serotonin 2C receptor antagonist can attenuate this cue-induced risk preference in rats. However, the neurocognitive mechanisms mediating this effect are currently unknown. We therefore assessed whether the serotonin 2C receptor antagonist RS 102221 is able to attenuate cue-enhanced risk preference via its actions in the lateral orbitofrontal cortex (lOFC) or prelimbic (PrL) area of the medial prefrontal cortex (mPFC). A total of 32 male Long–Evans rats were trained on the cued version of the rat gambling task (rGT), a rodent analog of the human Iowa gambling task, and bilateral guide cannulae were implanted into the lOFC or PrL. Intra-lOFC infusions of the 5-HT2Cantagonist RS 102221 reduced risky choice in animals that showed a preference for the risky options of the rGT at baseline. This effect was not observed in optimal decision-makers, nor those that received infusions targeting the PrL. Given prior data showing that 5-HT2Cantagonists also improve reversal learning through the same neural locus, we hypothesized that reward-concurrent cues may amplify risky decision-making through cognitive inflexibility. We therefore devalued the sugar pellet rewards used in the cued rGT (crGT) through satiation and observed that decision-making patterns did not shift unless animals also received intra-lOFC RS 102221. Collectively, these data suggest that the lOFC is one critical site through which reward-concurrent cues promote risky choice patterns that are insensitive to reinforcer devaluation, and that 5-HT2Cantagonism may optimize choice by facilitating exploration.
НЕЙТРАЛЬНА ВАРТІСТЬ ГРОШЕЙ У ПРАКТИЦІ МОНЕТАРНОГО РЕГУЛЮВАННЯ
Authors: ДАНИЛИШИН Богдан , БОГДАН Іван
Published: November 2021

Проблематика оцінки рівня нейтральної процентної ставки є центральним питанням у процесі теоретичного обґрунтування прийняття рішень щодо процентної політики в практиці центральних банків. У результаті опрацювання теоретичних джерел, дослідницьких матеріалів міжнародних організацій та центральних банків систематизовано фактори нейтральної процентної ставки, узагальнено методи її оцінки, виявлено їх переваги та недоліки. Фактори нейтральної ставки систематизовано за принципом їх впливу на попит чи пропозицію грошей в економіці. Встановлено, що єдиного загальноприйнятого теоретико-методичного підходу до визначення нейтральної ставки в сучасній практиці не існує. Широка варіація методів з різним ступенем покладання на теоретичну основу (від суто математичних технік фільтрації до складних макроекономічних моделей загальної рівноваги) створює поле для нових науково-практичних досліджень. З’ясовано, що ключовим дискусійним питанням у моделях оцінки нейтральної ставки є формалізація співвідношення між ефектами зовнішніх та внутрішніх чинників, що є особливо важливим для країн з малою відкритою економікою. Увагу приділено методу оцінки нейтральної ставки на основі правила непокритого процентного паритету, що застосовується в національній практиці монетарного регулювання. Виявлено системні вади даного методу на основі дослідження його теоретичних засад і результатів практичного застосування в умовах української економіки. Обґрунтовано доцільність запровадження в практику монетарного регулювання України альтернативного методичного інструментарію оцінки нейтральної ставки на основі розробок Т. Лаубаха і Дж. Вільямса з адаптацією до умов відкритої економіки, що дозволить посилити роль внутрішніх факторів розвитку, зокрема в зміні потенційного ВВП і заощаджень як важливих детермінантів нейтральної вартості грошей.
РОЗВИТОК СОЦІАЛЬНОЇ ЕКОНОМІКИ В ПОЛЬЩІ: ДОСВІД ДЛЯ УКРАЇНИ
Authors: СІМАХОВА Анастасія
Published: November 2021

Розвиток соціальної економіки сприяє підвищенню добробуту населення, що є одним з головних завдань будь-якої держави. Наявність певних соціальних проблем в Україні потребує аналізу іноземних практик реалізації соціальних цілей для зростання рівня життя населення. В умовах євроінтеграційних прагнень такою державою для України є сусідня Польща.Для розкриття цих питань проаналізовано позитивний досвід розвитку соціальної економіки та забезпечення зайнятості в Польщі й окреслено можливості його застосування в Україні. Розглянуто практику соціальної економіки в Польщі, порівняно Україну і Польщу за окремими соціальними індикаторами (кількістю закладів соціального забезпечення, рівнем безробіття, рівнем зайнятості, середньою місячною заробітною платою, рівнем самозайнятості), окреслено напрями реалізації соціального розвитку в Польщі з акцентуванням на їх можливому використанні в Україні. Розглянуто таксономічні методи для визначення соціального розвитку Польщі та змін у сфері ринку праці обох країн. Виокремлено основні детермінанти польської моделі соціальної економіки: стабільний економічний розвиток, що сприяє підвищенню рівня життя; низький рівень безробіття; розвинута соціальна інфраструктура; підвищення середньої заробітної плати; розвинутий недержавний сектор соціального забезпечення; стабільність ринку праці та його здатність адаптуватися до нових викликів.Наголошено на низці проблемних питань у розвитку соціальної економіки в Україні, зокрема відзначено низький рівень заробітної плати порівняно з сусідніми європейськими країнами; високий рівень безробіття; низький рівень самозайнятості населення; високий рівень тіньової економіки. На основі аналізу позитивного досвіду Польщі окреслено ряд можливих напрямів розвитку соціальної економіки в Україні.
Linguosophy of war and man in works of fiction by Borys Humenіuk
Authors:   Institute of the Ukrainian Language of National Academy of Sciences of Ukraine, Bybyk Svitlana
Published: November 2021

This article investigates the wartime poetry and prose by Borys Humenіuk dedicated to the current war in Eastern Ukraine started in 2014. Being of different genres, his works are marked by common through associative and figurative lines. Emphasis is placed on the ways of verbalization of the philosophy of war as an author’s interpretation of concrete sensory images provided by the artist as a direct participant in hostilities. There are two main associative and figurative lines, i.e., war — man — nature and life — death. The actualization of the military lexicon in the Ukrainian writing style is emphasized. Emphasis is also placed on the stylistic functions of a national and general cultural set of symbols (words) which reveal archetypal semantics in the structure of metaphorical and epithetical images. This article discusses such individual features of Humeniuk’s language creativity as an actualization of stylistics of a numeral, number, and digital code. Humeniuk’s poetic and prose language contains lyric-epic characteristic features. The epithets and metaphors of end-to-end associative image lines have been imprinted by the sublingual stylistic category of subjectivization. Linguosophy of man and war actualizes archetypal associative and figurative components, sacred, folklore, and surrealist (mythogenic) semantics of real phe nomena. The epithets and metaphors of Humeniuk’s Poems from the War and 100 Short Stories about the War created and united the military, socio-political, and intimately lyrical segments of the Ukrainian language picture of the world. These verbal and figurative mechanisms actualized the concrete sensory content, semantic, conversational casual and ironic, filling of certain cross-cutting lines. Humeniuk’s language attracts attention by expressive individual worldviews, the characteristic structural diversity of epithetics, intellectualized metaphors, which interact comprehensively and create deeply psychologized pictures of life during the war. Keywords: language of fiction, through associative-figurative lines, metaphor, epithet, numeral, wordsymbol, archetype.
Onomastic heritage in diachrony: On the material of oikonyms in the Kyiv region
Authors:   Institute of the Ukrainian Language of National Academy of Sciences of Ukraine, Karpenkо Olha
Published: November 2021

This article is devoted to the issues of historical oikonyms, whose general background is illustrated by etymological comments on specific examples from the oikonymicon of the Kyiv region. The etymology of an oikonym is not limited to the analysis of the etymon but also refers to the development of a particular word in general. Conceivably, reconstruction of the original oiko- nymicon is hardly possible, but a new discovery, even the attestation of a hitherto unknown renaming contributes to furthering our knowledge about the onomastic heritage. The article presents fragments of word-formation and etymological research relatable to the Kyiv region. The author reconstructs some Proto-Slavic forms, fills gaps in practically destroyed lexical nests, and looks in the lost appellatives and anthroponyms. Since the disappearance of words from the historical vocabulary is natural, the lexical basis of the onym, e.g., Berezan, Deremezna, Shkneva, largely remains almost the only evidence of plausible East Slavic features. The author uses the comparative-historical (etymological) method and the method of internal reconstruction. This is a reliable way not only to reconstruct the lost lexical structure of the language and local dialect rarities tending to enrich the lexicon but also to discover ethnic movements and migration processes of the population on both the right and left banks of the Dnieper River. Keywords: oikonym, etymology, word-forming model, anthroponym, appellative.
Stochastic Volatility Estimation of Stock Prices using the Ensemble Kalman Filter
Authors: Mahatma Yudi , Hadi Ibnu
Published: November 2021

AbstractVolatility plays important role in options trading.  In their seminal paper published in 1973, Black and Scholes assume that the stock price volatility, which is the underlying security volatility of a call option, is constant.  But thereafter, researchers found that the return volatility was not constant but conditional to the information set available at the computation time.  In this research, we improve a methodology to estimate volatility and interest rate using Ensemble Kalman Filter (EnKF).  The price of call and put option used in the observation and the forecasting step of the EnKF algorithm computed using the solution of Black-Scholes PDE.  The state-space used in this method is the augmented state space, which consists of static variables: volatility and interest rate, and dynamic variables: call and put option price. The numerical experiment shows that the EnKF algorithm is able to estimate accurately the estimated volatility and interest rates with an RMSE value of 0.0506.Keywords: stochastic volatility; call option; put option; Ensemble Kalman Filter. AbstrakVolatilitas adalah faktor penting dalam perdagangan suatu opsi.  Dalam makalahnya yang dipublikasikan tahun 1973, Black dan Scholes mengasumsikan bahwa volatilitas harga saham, yang merupakan volatilitas sekuritas yang mendasari opsi beli, adalah konstan. Akan tetapi, para peneliti menemukan bahwa volatilitas pengembalian tidaklah konstan melainkan tergantung pada kumpulan informasi yang dapat digunakan pada saat perhitungan.  Pada penelitian ini dikembangkan metodologi untuk mengestimasi volatilitas dan suku bunga menggunakan metode Ensembel Kalman Filter (EnKF).  Harga opsi beli dan opsi jual yang digunakan pada observasi dan pada tahap prakiraan pada algoritma EnKF dihitung menggunakan solusi persamaan Black-Scholes.  Ruang keadaan yang digunakan adalah ruang keadaan yang diperluas yang terdiri dari variabel statis yaitu volatilitas dan suku bunga, dan variabel dinamis yaitu harga opsi beli dan harga opsi jual. Eksperimen numerik menunjukkan bahwa algoritma ENKF dapat secara akurat mengestimasi volatiltas dan suku bunga dengan RMSE 0.0506.Kata kunci: volatilitas stokastik; opsi beli; opsi jual; Ensembel Kalman Filter.
Análisis genético de cinco polimorfismos de nucleótido simple de caseínas lácteas obtenidos con chips genómicos en ganado Holstein de Antioquia, Colombia
Authors: Padilla-Doval J. , Zambrano-Arteaga J. C. , Echeverri-Zuluaga J. J. , López-Herrera A.
Published: November 2021

Los polimorfismos genéticos asociados con las caseínas de la leche son de gran importancia, ya que pueden ser usados como marcadores genéticos para mejorar el rendimiento productivo en los hatos lecheros. El objetivo de este estudio fue evaluar la diversidad y estructura genética de 5 SNP de caseínas de la leche, obtenidos con chips genómicos en vacas y toros de raza Holstein en Antioquia (Colombia). Fueron muestreados 113 animales de raza Holstein en 3 regiones del departamento de Antioquia (norte, centro y oriente) y un cuarto grupo de sementales comerciales. Los animales fueron genotipificados con chips genómicos de alta densidad (Illumina BovineHD e Illumina SNP50 v2), a partir de los cuales se identificaron 5 SNP (ARS-BFGL-NGS-8140, BTA-77380-no-rs, BTA-32346-no-rs, BTB-00821654 y ARS-BFGL-NGS-15809). Para cada SNP se realizó un análisis genético mediante un análisis de varianza molecular (Amova) usando el software GenAIEx 6.501. Los SNP con mayor heterocigosidad total (HT) fueron ARS-BFGL-NGS-8140 y BTA-32346-no-rs, con resultados cercanos al 45%; sin embargo, la HT para ARS-BFGL-NGS-15809, BTA-77380-no-rs y BTB-00821654 estuvo por debajo del 15%. El SNP con mayor diversidad genética fue BTA-32346-no-rs (Ho – He = 0,06; p < 0,05). En esta investigación se evaluó una subpoblación de toros comerciales extranjeros, en la cual se obtuvieron frecuencias alélicas y genotípicas similares a las obtenidas para las subpoblaciones locales, sugiriendo que los alelos de los toros muy posiblemente están fijados en dichas subpoblaciones, por lo que la estructura y diversidad genética tienden a ser bajas en la muestra de estudio.
Christopher G. White, Other Worlds: Spirituality and the Search for Invisible Dimensions.
Authors: Silva Francisco
Published: November 2021

Christopher G. White, Other Worlds: Spirituality and the Search for Invisible Dimensions. Cambridge, MA: Harvard University Press, 2018, 376 pp, ISBN: 9780674984295 (hbk). $37.00 / £29.95 / €33.50.
Cristina Rocha, Mark Hutchinson and Kathleen Openshaw (eds), Australian Pentecostal and Charismatic Movements.
Authors: Buch Neville
Published: November 2021

Cristina Rocha, Mark Hutchinson and Kathleen Openshaw (eds), Australian Pentecostal and Charismatic Movements. Leiden/Boston: Brill Publications, 2020, pp. 304. €55.00/$64.00. ISBN 9789004425781 (pbk).
Further Contextualizing Racial Identity: Multiracial Students at Hispanic-Serving Institutions
Authors: Cristobal Nik , Johnston-Guerrero Marc P. , Garcia Gina A.
Published: November 2021

Despite the recent growth of literature on multiracial college students, there is still limited understanding about multiracial students at Minority-Serving Institutions (MSIs). This qualitative study explores the interplay of racialized identity and the unique contexts of Hispanic-Serving Institutions (HSIs) using data from eight multiracial students attending two HSIs in the Midwest. Findings explore how students made sense of their multiracial identities within specific ecological contexts of HSIs, including a mesosystem of diversity and inclusion and an exosystem of Latinidad. Overall, multiracial students generally felt included and provide a promising platform to better understand the unique positioning of HSIs in serving an increasingly diverse student body.
Quantifying Bottlenecks in Manufacturing
Authors: Tito Maria D. , Doniger Cynthia , Gilbert Charles E.
Published: November 2021

Shortages of key components and logistics problems have constrained factory output since the start of the year. Numerous anecdotes and survey measures have highlighted the emergence of supply chain bottlenecks and other supply constraints; to complement those qualitative characterizations, this note proposes a novel methodology to quantify bottlenecks in the manufacturing sector.
Albinism in the Ancient Mediterranean World
Authors: Hilton, John L.
Published: November 2021

The discovery of DNA in the 20th century and recent biomedical research into the human genome in Southern Africa have shed much light on the diagnostic, epidemiological, and sociological aspects of albinism. Less attention has been given to the historical evidence for the condition and its religious context, especially in the ancient Mediterranean World. This article assembles the meagre evidence for albinism in antiquity and investigates to what extent it was treated as 'sacred'.
Traveling Islamophobia in the Global South: Thinking Through the Consumption of Malala Yousafzai in India
Authors: Kunnummal Ashraf , Esack Farid
Published: November 2021

Malala Yousafzai (1997-) became an international icon after Pakistan-based Tehrik-i-Taliban militants attacked her on her way to school on October 9, 2012. In the following days, the global media gave extensive coverage to the attack from multiple narrative positions. This article argues that the traveling of Yousafzai as an image of a Muslim girl's right to education was instru-mentalized in the context of Kerala, South India, to deny Muslims the right to political agency. By analyzing the traveling of Islamophobia in the Global South, this article shows how the gender-based stereotypes of Islamic political subjectivity were reproduced through the figure of Yousafzai. By looking into the particularities within the Global South, this article argues that Islamo-phobia as a discourse is now part of a global economy within which the threat of Muslim subjectivity is applied in unique ways.
Lost to Presence: The Entanglements of Writing, Protestant Christianity, and Empire in the 19th-Century Southern Africa
Authors: Molapo Sepetla
Published: November 2021

This essay takes interest in a dialectical relationship between writing as affirmation and writing as a system of codification. It explores this dialectic as it relates to the interaction between Sotho-speaking communities and Protestant Christian missionaries in the 19th-century Southern Africa. It shows that this dialectical relationship dissolves truth as a construct of writing as affirmation because it is informed by an ontology of force that conceives of truth (Christian truth in this case) as an outcome of victory over an adversary. This ontology of force, in which Christianity participates, is a consequence of a modern metaphysics that splits individual and divine will. Cut off from participation in divine will, the autonomous will of Protestant Christian missionaries became the basis for organizing the world of the 19th-century Sotho speakers. This opened doors for Christianity to participate in the broader imperial project of the racial subordination of colonized people that Sotho speakers resemble. The consequence of this was not only the delegitimization of personhood as a construct of indigenous African religion, but also the introduction of conceptions of personhood that partook of race and racism.
Revised recognition of a high Sierran Potentilla (Rosaceae) as Potentilla amicarum
Authors: Ertter Barbara
Published: November 2021

Potentilla amicarum Ertter is provided for plants from high elevations (2700–3700 m) in the southern and central Sierra Nevada, and also the White and Sweetwater mountains of California, that have most often been treated as depauperate P. drummondii or P. bruceae, or else P. breweri with subpinnate leaves. The name P. breweri var. viridis Jepson has sometimes been applied to these plants, but the type of that name is inter-preted as the hybrid of P. wheeleri and P. breweri. A hybrid origin is hypothesized involving P. breweri, P. drummondii, and/or P. glaucophylla. The size range and elevation of P. bruceae in recent floristic treatments is adjusted accordingly, and the distribution of P. drummondii in California is discussed.
Endemic plants of the central grassland of North America: distribution, ecology, and conservation status
Authors: Locklear James H.
Published: November 2021

This paper enumerates the endemic plants of the Central Grassland of North America. The Central Grassland encompasses the full extent of the tallgrass, mixed-grass, and shortgrass prairie ecological systems of North America plus floristically related plant communities that adjoin and/or interdigitate with the midcontinental grasslands including savanna-open woodland systems, shrub-steppe, and rock outcrop communities. There are 382 plant taxa endemic to the Central Grassland, 300 endemic species (eight of which have multiple subspecific taxa endemic to the region) and 72 endemic subspecies/varieties of more widely distributed species. Nine regional concentrations of endemic taxa were identified and are described as centers of endemism for the Central Grassland: Arkansas Valley Barrens, Edwards Plateau, Llano Estacado Escarpments, Llano Uplift, Mescalero-Monahans Dunes, Niobrara-Platte Tablelands, Raton Tablelands, Red Bed Plains, and Reverchon Rocklands. In addition to hosting localized endemics, these areas are typically enriched with more widely-distributed Central Grassland endemics as well as peripheral or disjunct occurrences of locally-rare taxa, making them regions of high floristic diversity for the Central Grassland. Most of the endemics (299 or 78%) are habitat specialists, associated with rock outcrop, sand, hydric, or riparian habitats. There is a strong correlation between geology and endemism in the Central Grassland, with 59% of the endemics (225 taxa) associated with rock outcrop habitat. Of the 382 Central Grassland endemics, 124 or 33% are of conservation concern (NatureServe ranking of G1/T1 to G3/T3). Of these at-risk taxa, 78 or 63% are primarily associated with one of the centers of endemism identified in the study. It is hoped these findings will be useful in focusing conservation action on the habitats, ecological associations, and regions of the Central Grassland that host the highest concentrations of unique and at-risk plant species and associated biological diversity.
Struthanthus (Loranthaceae) variation in Venezuela: a numerical approach
Authors: Kazandjián Aniuzka
Published: November 2021

Struthanthus Mart. is a large genus in the Loranthaceae occurring in the New World Tropics. Although 12 species are currently recognized in Venezuela, many herbarium specimens are difficult to positively identify because of the ambiguity of some characters that are used to distinguish species. A multivariate analysis of 144 herbarium specimens based on 17 characters recognized the following 5 groups: S. corymbifer Rizzini, S. gracilis (Gleason) Steyerm. & Maguire, S. phillyreoides (Kunth) Blume, S. syringifolius Mart. and S. terniflorus (Klotzsch) Eichler, plus the discrete S. martianus Dettke & Waechter. A key and descriptions for all species recognized in this analysis for Struthanthus in Venezuela are provided.
Procambial and cambial variants in Serjania and Urvillea species (Sapindaceae: Paullinieae)
Authors: Lopes Willian Adriano Lira , Souza Luiz Antonio de , Almeida Odair José Garcia de
Published: November 2021

For the purpose of comparing the structure of vascular cylinders, and procambial and cambial variants of Serjania Miller and Urvillea Kunth species, we studied the stems of five species, in order to add to the structural knowledge of these genera belonging to the widely distributed Sapindaceae family. Stems of sampled species were collected at “Estação Ecológica do Caiuá,” Diamante do Norte (PR), Brazil; and were analyzed using traditional anatomical techniques. We analyzed five species of two genera from the Paullinieae tribe: three species of Serjania (S. communis, S. fuscifolia, and S. meridionalis) and two of Urvillea (U. leavis and U. ulmacea); in which we describe the primary and secondary growths, the number of peripheral cylinders, the type of cylinders concerning its origin, the type of stem, and the origin of the cambial or tissue variant. Serjania stems exhibit the compound and corded types, while the cleft and mixed (cleft/corded) types have been recorded in Urvillea species. All species have peripheral vascular cylinders in which the stems of S. communis and S. fuscifolia form the procambial and cambial variants during primary growth, whereas the stems of S. meridionalis, U. leavis, and U. ulmacea develop the cambial variants during secondary growth.
Habranthus tubispathus (Amaryllidaceae/Liliaceae), new to the flora of Mississippi, U.S.A.
Authors: Barbour Philip J.
Published: November 2021

Habranthus tubispathus (L’Hér.) Traub is reported as new to the flora of Mississippi, U.S.A.
[RETRACTED] Guardian Blood Balance Reviews: Healthy Blood Levels Does it Really Work? v1
Authors: Blood Balance Guardian
Published: November 2021

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[RETRACTED] Golly CBD Gummies Reviews – Does it work? Shocking Scam Report Reveals Must Read Before Buying v1
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Published: November 2021

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Validade do questionário internacional de atividade física (IPAQ) em idosos: uma revisão integrativa da literatura
Authors: Miranda Kessketlen Alves , Da Silva Ivaldo Miranda , Cerqueira Juliana Cecilio , Santos Maria Paula Maia dos
Published: November 2021

Introdução: O questionário Internacional de Atividade Física (IPAQ) tem sido amplamente utilizado nas pesquisas. É considerado uma boa ferramenta de medição de Atividade Física (AF), no entanto, este questionário não é específico para idosos, geralmente, é aplicado à população em geral. Objetivo: Realizar uma Revisão Integrativa  da Literatura apresentando os estudos que investigaram a validade do IPAQ na avaliação de AF em idosos nos últimos seis anos. Métodos: Foi realizada uma Revisão Integrativa da Literatura nas bases de dados PUBMED, BVS e SCOPUS, relativa aos anos de 2014 a 2020, utilizando-se os descritores: Elderly, Aged, IPAQ questionnaire validity, Physical Activity e Exercise. Resultados: Foram selecionados oito artigos cuja metodologia apresenta a validade do IPAQ, na avaliação em idosos com idade ≥65 anos. Seis dos artigos selecionados apresentaram em suas metodologias a avaliação realizada pelo IPAQ-L (versão longa), e apenas dois artigos apresentaram IPAQ-S (versão curta). Conclusão: O IPAQ- L tem sido amplamente utilizado para avaliar os níveis de AF e comportamento sedentário (CS) em idosos. As evidências demonstram que a aplicação do questionário combinado com os dados do acelerômetro, tem mostrado medições satisfatórias, no entanto, futuras versões devem ser estruturadas para atender a este público específico.
Is it appropriate or not to have a surgical intervention for uterine fibromes that do not give seizures in old age?
Authors: Kakushkin N.
Published: November 2021

A 57-year-old patient, who has not worn blood for 2 years and has never had abdominal pain or uterine bleeding, was operated on to remove the uterus and appendages completely (from the vagina), because the doctor who had heard of the patient preceded her with uterine fibromia.
Pregnancy complicated by fibroids
Authors: Sheinis L.
Published: November 2021

The author gives a detailed history of a patient in whom during childbirth a fibroma was diagnosed, which completely impeded delivery.
Accidental vaccination of cancer with complete removal of the uterus
Authors: Bonstedt G. E.
Published: November 2021

(Boan. Gaz. Botkin 1898, No. 11 and 12, pp. 473 and 530). There are facts of secondary cancer diseases, which cannot be explained otherwise than by the infectiousness of cancer. These facts were observed in their natural course and were tested empirically.
In memory of K.F.Slaviansky
Authors: Team Editorial
Published: November 2021

Not yet five years have passed since that day (December 9, 1893), when in this very hall the Obstetric and Gynecological Society honored its then chairman, Kronid Fedorovich Slavyansk, on the occasion of his 25th anniversary.
Current issues of effectiveness and safety of uterine artery embolization in patients with uterine leiomyoma
Authors: Korobova Polina G. , Sulima Anna N. , Mkrtchyan Azat A. , Rumyantseva Zoya S. , Korobov Sergey A.
Published: November 2021

Uterine artery embolization (UAE) is a highly effective minimally invasive method for treating patients with symptomatic uterine leiomyoma, which becomes more popular between those refusing hysterectomy and conservative myomectomy for a number of reasons, including unrealized fertility. Some issues of UAE effectiveness and safety are still being investigated: optimization of method in order to guarantee radiation safety, extension of indications for UAE, recurrence risk prediction, choice of tactics according to individual anatomy of local blood supply, fertility impact assessment. The results of investigations demonstrate safety and high efficacy of UAE in the treatment of symptomatic uterine leiomyoma on condition that modern techniques of procedure optimization and an individualized approach to the selection and treatment of patients are used.
Features of the medical history and pregnancy outcomes in women with antiphospholipid syndrome depending on correction methods
Authors: Kravchenko Elena N. , Goncharova Anastasia A. , Kuklina Larisa V.
Published: November 2021

Hypothesis/aims of study. The aim of this study was to evaluate the features of the medical history and pregnancy outcomes in women with miscarriage and antiphospholipid syndrome depending on the methods of its correction.
Study design, materials and methods. A prospective cohort study was conducted, in which a total of 137 pregnant women with a history of abortion and antiphospholipid syndrome were examined. The women were divided into two groups according to the principle of the presence or absence of plasmapheresis procedures in the scheme of miscarriage therapy at the pregravid stage. Group I (main) consisted of individuals (n = 73), who were treated with the inclusion of plasmapheresis at the pregravid stage; group II (comparison) included women (n = 64), who were not given efferent therapy.
Results. Antiphospholipid syndrome was more common in patients with a complicated obstetric and gynecological history. As a result of persistent infection, chronic endometritis and salpingo-ooparitis were more often observed in patients with TORCH infection. The titer of antiphospholipid antibodies, regardless of the presence or absence of TORCH infection, decreased after plasmapheresis, such positive dynamics being observed only in patients with a history of gestational losses of less than four.
Conclusion. The level of reduction of antiphospholipid antibodies in relation to the initial values was 6095%, which indicates the optimal choice of the characteristics of plasmapheresis therapy and its duration.
Influence of a complex of the factors of a radiating catastrophe on a state reproductive health of the women
Authors: Bezhenar V. F.
Published: November 2021

Some data in an article about learning of influence of a complex of the factors Chernobyl's catastrophe on reproductive health of the women which taking part in liquidations accident, living and evacuated from radioactive-polluted of territories (RPT) are represented of. On the basis of spent researches dependence between effect of the factors of radiating accident and growth of a gynecology and somatic diseases of the women-liquidators and evacuated from RPT in 8 years after accident is detected. A leading place of gynecology pathology in a structure of diseases of the women-liquidators is shown. Significant number of the liquidators (18.7 %) with a central level of a defeat in an endocrine system is detected. Is installed, that the influence of the factors of radiating accident to a female organism is accompanied by creation disbalance in the system immunoregulatory of cells. The women which live in conditions of chronic effect of small of dozes ionizing radiation, develops secondary immunodeficiant a state as violation as cell-like, and humoral of a link of immunity. Creation of an unstable state henom at women-liquidators of consequences of accident, saved on stretch 8-9 years after accident is detected.
To a problem of the markers of vessels wall at EPH-gestosis
Authors: Ailamasian E. K. , Zainulina M. S. , Petrishev N. N.
Published: November 2021

Content in blood of markers of damage of a vessel wall (factor Willebrand, tissue of a catalyst plasminogen, cells circulating in blood endothelium), and also intravessel an aggregate platelet and uterine - placental bloodcurrent at 205 patients, among which woman with physiological current of pregnancy and with EPH-gestosis of a various degree of weight is investigated. The patients with nephropathy and preeclampsy were divided into groups depending on a method of treatment.

The 46 pregnant with EPH-gestosis of a various degree of weight was carried by clofelin in a daily doze 0,00015-0,0003 g during 7-10 days, 42 women therapy (the course doze 25,5-27 g of dry substance) is spent magnesium, 59 pregnant received clofelin and magnesium therapy in the above-stated dozes. The group of comparison formed 38 patients.

It was shown the important value of a research of markers of damage endothelium for diagnostics, definition of a degree of weight and control for efficiency of therapy pregnant with EPH-gestosis. Clofelin and magnesium, used for treatment of pregnant with EPH-gestosis as is independent, and in a combination, have endotheliumprotection operation, as reduce in authentic decrease of a content in blood of a marker of vessel's disorders of circulating cells endothelium, and also reduce intravessel an aggregate of platelets and improve uterine-placental bloodcurrent.
Rare cases of combined gunshot injuries of female genital organs in peace time
Authors: Kira E. F. , Tsvelev Lu. V. , Kaplun I. B. , Zhirnovoi V. M. , Divin S. V.
Published: November 2021

In the article analysis two rare cases of combined gunshot injuries of female genital organs in peace time were represented.
Application computer monitoring of parameters of the clinical analysis of blood for forecasting and early diagnostics of postoperative inflammatory complications
Authors: Dolgov G. V.
Published: November 2021

Automated system computer monitoring the Prognoz was developed on the basis of mathematical modeling of a database of the clinical analysis of blood of 334 women with non complicated current postoperation period and 133 patients with postoperations inflammatory complications. Application of a system the Prognoz in clinical practice permits to prognosticate before the operation in 68,8% cases non complicated current postoperation period and in 93,0% cases on the 3-d day after operation to diagnose initial postoperations inflammatory complications.
Experience of microsurgical tubes operation for sterility in women
Authors: Mgeladze B. N.
Published: November 2021

Analysis of 140 cases microsurgical operation on fallopian tubes was made. On the basis of received results the conclusion is done that using of microsurgical operation is justified at recanalisation, imposing tubo-tubarian anastomosis and fimbrioplastics. At the same time, the tubes sterility at availability permanent current inflammatories processes with damaged at tubes on the long line and thereto with form formations of sactos are not subject of microsurgical correction connection with small quantity set in pregnancies. Thus the application of the microsurgical correction is shown at hightly motivated ill with consideration of contra-indications offered by author.
Efferent therapy in the complex treatment of EPH-gestosis
Authors: Vetrov V. V.
Published: November 2021

In the review the data are submitted, which witnessed about expediency of using detoxication therapy in the complex treatment of EPH-gestosis.
The peculiarity of protein degradation under the pregnancy with gestosis and diabetes
Authors: Burmistrov S. O. , Kovaleva T. G. , Buzurukova P. S. , Kosheleva N. G. , Arutjunyan A. V.
Published: November 2021

Some groups of women with normal pregnancy with pregnaizcy aggravated by gestosis and diabetes I and II were examined. The level of middle molecules (MM) and protein peroxidation (PP) were measured in the blood serum. The activity of ceruloplasmin (CP) and oxitocinase (ОС) were evaluated too. The level of MM was measured in the urine. More active processes of protein degradation were shown under normal pregnancy in comparison with unpregnant group. These processes reflect both free radical reaction and proteolitic processes. Activation of proteolisis results in evaluated level of MM. The MM content and PP level were not increased significantly in the group with gestosis. But the elevated activity of ceruloplasmin (on 15%) under gestosis reflects an activation of oxidative stress and free radical processes. It was found an increased serum and decreased urine level of MM and in the group of women with complicated diabetes I. The women with diabetes II have shown elevated CP activity (on 14%) too and increased level of PP (on 14%). It was supposed that MM may be a toxic factor witch damage placenta and foetus under diabetes I and II. The free radicals may be a factor which hurt tissue of placenta and foetus under diabetes II.
Pitocin receptorsand efficiency of labor activity
Authors: Abramchenko V. V. , Savitsky A. G. , Kaplenko O. V.
Published: November 2021

Pitocin is the most widely used preparation for advance pregnancy interruption. In the review of the literature the modern data is given about a role of pitocin receptors in successful labor induction and amplification of labor activity. There is also given data on the regulation opportunity of pitocin receptors level with estrogens, prostaglandines and their significance in OB practice. This data needs to be taken into account for drugs development to advance the pregnancy interruption.
Positive experience of replacement hormonal therapy in patients with climacteric syndrome with Proginova, Cyclo-Proginova and Climen
Authors: Vishnevsky A. S. , Safronnikova N. R. , Melnikova N. U. , VIadykina T. N. , Artamonova E. A.
Published: November 2021

At 75 patients (average age 57,2 years, average postmenopausal period 3,5 years) the hormonal replacement therapy is carried out because of climacteric syndrome with Proginova (29 women), Cyclo-Proginova (25 women) and Climen (21 women). The preparations were nominated in a cyclic mode (average duration of treatment has made 5,6 cycles).

There is marked a high therapeutic effect as reduction of frequency of vegetovascular climacteric frustrations in Proginova application (83 % ), Cyclo- Proginova (84 %) and Climen (96%).

The application of Proginova, Cyclo-Proginova and Climen resulted in normalization of lipid spectrum of blood by 3 month of treatment, that was expressed in authentic decrease in initially raised cholesterin and cholesterin of low density, with increase of the contents of cholesterin fraction of high density.

The marked normalization of lipid spectrum as a result of hormonal replacement therapy can be considered as pathogenic influence directed on normalization in age - associated metabolic infringements in female organism.
Clinical experience of «Divigel» application
Authors: Smetnik V. P. , Shestakova I. G.
Published: November 2021

The research, carried out by the authors, has shown high clinical efficiency of transdermal estrogen drug Divigel in climacteric disturbances treatment.
The life and scientific activity of professor Vasily Markovich Florinsky (1834-1899)
Authors: Tsvelev Yu. V.
Published: November 2021

Anatomical and physiological properties of a man are, as well known, variable, mobile and because of that under the influence of hereditary and physical environment may get improved or get worsened V.M.Florinsky (1866).
Shistozomatous salpingitis as a course for primary tubal- peritoneal infertility: A case report
Authors: Kira E. F. , Guriev A. V. , Povzun S. A.
Published: November 2021

The clinical case of shistozomatous salpingitis, that has become the course for primary tubal-peritoneal infertility is shown. Such diseases are rather rare for european countries, but widely spread in southern countries among women.
Diagnostic importance of endoteliogramm in pregnant woman with late gestosis diabetes mellitus
Authors: Zainullina M. S. , Mozgovaya E. V. , Niaury D. A.
Published: November 2021

Under the supervision there were 415 pregnant women with physiological pregnancy, late gestosis and suffering from diabetes mellitus. At application of a preparation Sulodexid in pregnant woman with diabetes mellitus I type was revealed an authentic improvement of diabetes indemnification. The contents of crates, circulating in blood and endothelium after Sulodexid treatment has authentically decreased.
Pediatrik hastada preseptal selülit ile ilişkili intrakraniyal enfeksiyon
Authors: OKUR AKŞAN İlknur , AKOĞLU Handan Ayhan
Published: November 2021

Sinüzit preseptal selülit, orbital selülit ve veya intrakraniyal enfeksiyonla bağlantılı olabilir. Preseptal selülit orbital septum anteriorundaki göz kapağı ve süperfisyal perioküler dokuların enfeksiyonu ya da enflamasyonuyla sınırlı bir durumdur.
Sigmoid volvulus: Comorbidity with neurological diseases
Authors: ATAMANALP Sabri Selcuk
Published: November 2021

Sigmoid volvulus: Comorbidity with neurological diseases
Postfeminist Bir Pazarlama Stratejisi Olarak Femvertising: Nike, Molped ve Elidor Reklamları Örneği
Authors: DİNÇ KIRLI Elzem Seren , TAN ÇAKIR Nilay
Published: November 2021

Günümüzde markalar, kadını merkezine alarak toplumsal cinsiyet eşitliğine vurgu yapan reklamlar
yapmaktadır. Postfeminist söylemlerden etkilenen bu markalar, kadın odaklı reklam çalışmalarıyla cinsiyet
eşitliği konusundaki algı değişimlerini pazarlama fırsatına dönüştürmektedir. Bu doğrultuda çalışmada,
toplumsal cinsiyet kalıplarına eleştirel yaklaşan femvertising akımının, feminist teorinin amacıyla
örtüşüp örtüşmediği tartışılmakta ve bu akımın, toplumsal cinsiyet eşitsizliğinin yeniden üretilmesine
nasıl etki edebileceği irdelenmektedir. Çalışma kapsamında Türkiye’de yayınlanan Nike, Molped ve
Elidor markalarına ait reklamlar postfeminist söylemler bağlamında Türkiye’nin kültürel konjonktürü
dikkate alınarak incelenmiştir. Nitel araştırma yaklaşımının kabul edildiği çalışmanın veri analizinde
göstergebilim kullanılmıştır. Çalışmanın bulgularından elde edildiği üzere, reklamın temel amacı satış
yapmak olduğu için bu tür reklamların da ürün ve satış odaklı olması kaçınılmazdır. Bu sebeple feminist
mücadeleye destek vermek amacıyla çekilen bu reklam filmlerinin de genel olarak ürün ve satış odaklı
olduğu düşünülmektedir. Ayrıca bu reklamlarda, kadınlara toplumsal cinsiyet rolleriyle yüklenen kalıp
yargılar değiştirilmek istenirken bu kalıpların dışında kalan kadınların ötekileştirilmesi söz konusudur. Bu
durum femvertising akımının, feminist ilkelere bağlı olmadığı müddetçe ve feminizmin anlamının yalnızca
bir reklam sloganına indirilmeye devam ettiği sürece kadınların eşitlik mücadelesinde rolü olmayacağını
düşündürmektedir.
The Role of Helicases and Helicase-like Proteins in Homologous Recombination
Authors:   , Deakyne Julianna , Mazin Alexander V.
Published: November 2021

Homologous recombination is important for repair of the most harmful types of DNA damage including DNA double-strand breaks, interstrand cross-links, and for chromosome segregation in meiosis. When a double-strand break occurs, the DNA ends are resected to create single-stranded overhangs that allow RAD51 recombinase to form a nucleofilament that searches for homologous DNA to initiate repair. Once the sequence is found, RAD51 exchanges DNA between the homologous pairs forming a Holliday junction at the point of exchange. The translocation of the Holliday junction by branch migration and resolution results in completion of repair. Several helicases are involved in homologous recombination, but their functions are not well understood. This study focuses on FANCJ helicase and RAD54 helicase-like protein that are highly conserved in eukaryotes. Mutations in either protein can lead to disease and cancer. FANCJ is implicated in interstrand cross-link repair but its specific function is unknown. Here, we characterized FANCJ's ability to clear RAD51 from both single-stranded and double-stranded DNA which can potentially have a regulatory function in homologous recombination. For the first time we identified a FANCJ mutation that disrupts the coupling of ATPase activity with its ability to translocate on DNA and disrupt RAD51-single-stranded DNA complexes. We then investigated the role of the RAD54 ATPase activity in stimulation of RAD51 strand exchange. We identified a small molecule streptonigrin that specifically binds RAD54 and inhibits its ATPase. Surprisingly, we found that RAD54's ability to stimulate RAD51 DNA strand exchange was not significantly affected by streptonigrin indicating a minor role of RAD54 ATPase in this process. In contrast, as expected streptonigrin strongly inhibited RAD54 branch migration activity. Our results demonstrate for the first time that RAD54 ATPase activity plays a different role in stimulation of DNA strand exchange than in branch migration of Holliday junctions. Furthermore, isolating discrete functions through chemical inhibition as well as the basic characterization of homologous proteins are critically important for understanding their innate functions.
Factors Influencing Dietary Diversity in Infants in India: Study Undertaken in Two Districts
Authors:   ASER Centre, New Delhi, India, Makkar Prerna , Vianna Candice S. , Vats Karishma , Mishra Pankhuri , Thomas Steffi Elizabeth , Singh Ayushi , Krishna Maitreiyee , Wadhwa Wilima
Published: November 2021

Adequate feeding practices in early life have a lasting impact on child nutrition and development. This paper examines the dietary diversity and its associated factors among children aged 6-12 months, in the age that they transition from breastfeeding to complementary feeding, in two districts in India: Udupi (Karnataka) and Sambalpur (Odisha). In 2019, a citizen-led survey, that can be scaled up further very rapidly and cost-effectively, was conducted covering 976 mothers of children below 1 year of age by 90 trained local volunteers. The survey tool uses the Knowledge, Access and Practices Framework and was developed, tested and refined over 4 years through diverse pilots in various locations in India. In the sample, only 12% children aged 6-12 months met the WHO’s minimum dietary diversity requirement. A linear probability regression model was used to assess significant factors for an adequate diversified diet intake in infants. Maternal education, child’s age and meal frequency were found to be significantly associated with dietary diversity. Other factors such as household wealth, gender of child, birth order and homegrown gardens did not present a strong association. Integrated interventions targeted at mothers and children that include nutrition education components into mothers’ education are more likely to be effective in improving infant dietary diversity.