bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGEMBANGAN MODUL BEDINGSANAKAN, BETETULUNGAN, DAN MAU HAJA BEKALAH BEMANANG UNTUK MENINGKATKAN INTERAKSI SOSIAL
Authors: Larissa Nidia Intan
Published: October 2023

Penelitian ini bertujuan mengetahui gambaran interaksi sosial dan kegunaan modul Bedingsanakan, Betetulungan, dan Mau Haja Bakalah Bamanang (BATUHA) untuk meningkatkan interaksi sosial pada siswa kelas XI SMA Negeri 6 Banjarmasin. Penelitian dengan pendekatan Mix-Method ini adalah kombinasi penelitian kuantitatif dan kualitatif yang digunakan secara bersama-sama. Penelitian pengembangan ini bertujuan mengembangkan dan menguji produk tertentu. Sampel pada penelitian ini adalah 6 orang siswa SMA Negeri 6 Banjarmasin. Data yang diperoleh kemudian dianalisis dengan teknik Wilcoxon. Hasil penelitian menunjukkan bahwa terdapat perbedaan sebelum dan sesudah menggunakan modul BATUHA dengan signifikan asymp sig (2 tailed) = 0.027 < 0.05. Data tersebut sejalan dengan uji modul pada tiga ahli dengan teknik analisis data Uji ICC. Dengan demikian, dapat disimpulkan bahwa modul BATUHA berguna, layak, dan tepat digunakan untuk meningkatkan interaksi sosial peserta didik kelas XI di SMA Negeri 6 Banjarmasin.
EFEKTIVITAS TEKNIK MODELLING UNTUK MENINGKATKAN EMPATI PADA PESERTA DIDIK KELAS XI DI SMK MUHAMMADIYAH 1 BANJARMASIN
Authors: Triany Annisa Eva
Published: October 2023

Empati merupakan kemampuan seorang individu untuk dapat turut serta menghayati apa yang orang lain rasakan atau merasakan sesuatu yang dirasakan oleh orang lain. Tujuan utama dalam penelitian ini untuk mengetahui efektivitas teknik modelling untuk meningkatkan empati padai pesertai didik kelas XI Akuntansi di SMK Muhammadiyah 1 Banjarmasin. Pada penelitian ini peneliti menggunakan jenis penelitian eksperimen dengan menggunakan bentuk Pretest-Posttest control group design. Sampel pada penelitian ini didapatkan dari hasil angket dengan kriteria tertentu melalui teknik purposive sampling yang berjumlah 4 orang. Hasil dari penelitiani ini menunjukkan bahwa berdasarkan pegujian dari data yang diperolehi dengan rnenggunakan rumusi Uji T-test menunjukkan bahwa thit >ttab (17,33> 4,303 dengan probabilitasi kesalahani 0.05 atau 5%). Jadi, dapat disimpulkan bahwa terdapat perbedaan tingkat empati sebelum dan sesudah diberikan teknik modelling melalu layanan konseling individual. Teknik modelling dalam layanan konseling individual terbukti efektif dalam meningkatkan empati pesertai didik kelas XI di SMK Muhammadiyah 1 Banjarmasin.
EFEKTIVITAS TEKNIK COGNITIVE RESTRUCTURING UNTUK MENGURANGI KECEMASAN AKADEMIK PADA SISWA KELAS XI MIA DI SMA NEGERI 12 BANJARMASIN
Authors: Herdayanti, Herdayanti,
Published: October 2023

Penelitian ini dilatarbelakangi oleh adanya kecemasan akademik yang tinggi pada siswa kelas XI MIA. Penelitian ini bertujuan untuk menguji keefektivan layanan konseling individual dengan teknik cognitive restructuring untuk mengurangi kecemasan akademik. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan metode eksperimen dengan rancangan pretest-posttest control group design yang berbentuk suatu rancangan eksperimen (true experimental design) penelitian ini dilaksanakan di SMA Negeri 12 Banjarmasin. Hasil penelitian ini menunjukkan bahwa berdasarkan pengujian dari data yang diperoleh menggunakan rumus Thit > Ttab 18 > 4,303 dengan probabilitas (0.05 atau 5%). Jadi keseimpulannya yang dapat diambil yaitu Ho ditolak dan Ha diterima berarti teknik cognitive restructuring dalam layanan konseling individual efektif terhadap mengurangi kecemasan akademik. Pada proses penelitian dilaksanakan ada catatan dalam menjalankan proses konseling individual dengan teknik cognitive restructuring untuk siswa diharapkan dapat makin menyadari bahwa diri sendiri dapat bersaing dengan teman sebaya dalam bidang akademik. Untuk guru BK dapat menggunakan teknik cognitive restructuring untuk mengurangi kecemasan akademik terbukti bahwa efektif.
The Absorption of Islamic Education Thought of KH. M. Hasyim Asy’ari through Teaching of Adab al-‘Alim wa al-Muta’allim among the Santri at the Pesantren Tebuireng
Authors: Rosyidin Muhammad Abror , Jasminto Jasminto , Jumari Jumari
Published: October 2023

K. H. M. Hasyim Asy’ari was founder and first chairman of Nahdhatul Ulama, one of the largest Islamic mass organization in Indonesia and the world. He was also a prominent scholar, with many of his books becoming the main references for Islamic boarding schools or pesantrens in Indonesia. The primary objective of this study is to systematically document, illustrate, and comprehend the cognitive absorption process of educational concepts in the book Adab al-’Alim wa al-Muta’allim, one of K. H. M. Hasyim Asy’ari’s masterpiece. This research examines the incorporation of Islamic educational philosophy in the book among santri, students of Islamic boarding school, of Pesantren Tebuireng Jombang, Indonesia. This study adopted a descriptive qualitative methodology including observational research techniques. The data collection processes involved the utilization of interviews, observations, and documentation, utilizing a snowball sampling technique. This study utilizes interactive analytical procedures consisting of three essential stages: data reduction, data presentation (also known as data display), and the formulation and validation of findings. The findings of the study indicate that a significant proportion of participants had a strong understanding of the content of the book and made concerted efforts to incorporate its teaching into their lives. Consensus was reached among all participants regarding the pedagogical significance of the book and its constructive impact on santri.
Soil Erosion and Landslide Susceptibility Mapping Using Rock Engineering System Methodology: The Case of Mandra Fatal Flash Flood (2017) in Western Attica, Greece
Authors: Tavoularis Nikolaos
Published: October 2023

Keywords: Mandra flash flood, soil erosion, slope failure, RES, mitigation measures, landslide susceptibility
A Survey of Numerical Simulation Tools for Offshore Wind Turbine Systems
Authors: Fadaei Saeid , Afagh Fred F. , Langlois Robert G.
Published: October 2023

Design, analysis, manufacture, and deployment of offshore wind turbines mounted on a floating base is a novel industry that is attracting interest from both academia and industry. In an effort to comprehend the sophisticated aerodynamics and hydrodynamics of the floating offshore wind turbines (FOWTs), numerical and physical modelling of these complex systems began to develop with their appearance. The strong coupling between the aerodynamics of the rotor-nacelle assembly (RNA) and the hydrodynamics of the floating platform makes modelling FOWTs a challenging task. However, the scaling mismatch between Froude scaling and Reynolds scaling made it more difficult to physically test scaled-down prototypes of FOWTs, whether in a wind tunnel or an ocean basin. In this regard, developing high-fidelity numerical modelling that is both cost-effective and accurate has been receiving increased attention as a potential replacement for or complement to physical testing. However, numerical engineering tools, which are frequently used in the offshore oil and gas industry, are known as mid-fidelity to low-fidelity tools and lack the degree of accuracy that is desirable for FOWTs. In recent years, a variety of numerical tools have been established or developed to uncover the complex nature of the dynamics of FOWTs. This study aims to provide a comprehensive survey of numerical tools available for simulating FOWTs, with a particular emphasis on horizontal axis wind turbines (HAWTs), assessing their capabilities and limitations.
Primary Series COVID-19 Vaccine Effectiveness among Health Care Workers in the Country of Georgia, March–December 2021
Authors: Katz Mark A. , Castro Madelyn Yiseth Rojas , Chakhunashvili Giorgi , Chitadze Nazibrola , Ward Caleb , McKnight C. Jason , Lucaccioni Héloïse , Finci Iris , Zardiashvili Tamila , Pebody Richard , Kissling Esther , Sanodze Lia
Published: October 2023

Background Healthcare workers (HCWs) have suffered considerable morbidity and mortality during the COVID-19 pandemic. Few data on COVID-19 vaccine effectiveness (VE) are available from middle-income countries in Europe. We evaluated primary series COVID-19 VE against laboratory-confirmed COVID-19 among HCWs in Georgia. Methods HCWs in six hospitals in Georgia were invited to enroll in a prospective cohort study conducted during March 19–December 5, 2021. Participants completed weekly symptom questionnaires. Symptomatic HCWs were tested by RT-PCR and/or rapid antigen test (RAT), and participants were routinely tested for SARS-CoV-2 by RT-PCR or RAT, regardless of symptoms. Serology was collected at enrolment, and quarterly thereafter, and tested by electrochemiluminescence immunoassay for SARS-CoV-2 antibodies. We defined primary series vaccination as two doses of COVID-19 vaccine received ≥14 days before symptom onset. We estimated VE as (1-hazard ratio)*100 using a Cox proportional hazards model with vaccination status as a time-varying covariate. Estimates were adjusted by potential confounders that changed the VE estimate by more than 5%, according to the change-in-estimate approach. Results Overall, 1561/3849 (41%) eligible HCWs enrolled and were included in the analysis. The median age was 40 (IQR: 30-53), 1318 (84%) were female, and 1003 (64%) had laboratory evidence of prior SARS-Cov-2 infection. At enrolment, 1300 (83%) were unvaccinated; By study end, 1082 (62%) had completed a primary vaccine series (69% BNT162b2 (Pfizer-BioNTech); 22% BBIBP-CorV (Sinopharm); 9% other). During the study period, 191(12%) participants had a new PCR- or RAT-confirmed symptomatic SARS-CoV-2 infection. VEa gainst PCR- or RAT- confirmed symptomatic SARS-CoV-2 infection was 58 (95%CI: 41; 70) for all primary series vaccinations, 68% (95%CI: 51; 79) for BNT162b2, and 40% (95%CI: 1; 64) for BBIBP-CorV vaccines. Among previously infected HCWs, VE was 58% (95%CI: 11; 80). VE against medically attended COVID-19 was 52% (95%CI: 28; 68), and VE against hospitalization was 69% (95% CI: 36; 85). During the period of predominant Delta variant circulation (July-December 2021), VE against symptomatic COVID-19 was 52% (95%CI: 30; 66). Conclusions Primary series vaccination with BNT162b2 and BBIBP-CorV was effective at preventing COVID-19 among HCWs, most of whom had previous infection, during a period of mainly Delta circulation. Our results support the utility of COVID-19 primary vaccine series, and the importance of increasing coverage, even among previously infected individuals.
The Effect of a Preconception Maternal Mentoring Program on Fetal Growth among Indonesian Women: Results of a Cluster Randomized Controlled Trial
Authors: Hadi Hamam , Nurunniyah Siti , Gittelsohn Joel , Alfiana Ratih Devi , Fatimatasari Fatimatasari , Lewis Emma Clare , Nurdiati Detty Siti
Published: October 2023

The prevalence of stunting in young Indonesian children is the highest among Southeast Asian Nations, and is associated with poor growth during the prenatal and early postnatal periods. A maternal mentoring program was developed for Indonesian women to improve birth outcomes. A cluster randomized control trial (CRCT) was conducted in three sub-districts of the Special Re-gion of Yogyakarta, Indonesia. A total of 384 eligible participants were randomly allocated to either intervention (received maternal mentoring program and standard care; n=189) or control (received standard care only; n=195). The maternal mentoring program provided preconception health education; health monitoring; and text message reminders for preconception women. Fetal growth was measured between gestational weeks 27-30 using estimated fetal weight generated from ultrasonographic measurement. Birth weight was measured within 24 hours of birth. A structured questionnaire captured women’s’ demographics, pregnancy readiness, and body mass index (BMI. After adjustment, fetal weight was 14% (95% CI: 5.1-23.0) higher in the intervention group than in the control group, and the average weight-for-length Z-score at birth was 0.16 (95% CI: 004-0.30) higher in the intervention group than in the control group. A maternal mentoring program was associated with improved fetal growth and birth weight in this population.
Cannabis and Endometriosis: The roles of the gut microbiota and the
endocannabinoid system
Authors: Farooqi Toobah , Bhuyan Deep , Low Mitchell , Sinclair Justin , Leonardi Mathew , Armour Mike
Published: October 2023

There is a growing interest in the endocannabinoid system and the gut microbiota. Both areas have been suggested to play a role in endometriosis, however this is yet to be studied comprehensively. The purpose of this narrative review is to identify the gaps in endometriosis research in the context of these two areas. It underscores the limited knowledge regarding the involvement of the endocannabinoid system and gut microbiota in endometriosis. Further research in these areas is essential to unlock the therapeutic potential of cannabis and enhance the understanding of endometriosis pathogenesis.
Clinical Assessment of Plaque Removal using a Novel Dentifrice containing Cellulose Microfibrils
Authors: Labib Mohamed E. , Perazzo Antonio , Manganaro James , Tabani Yacoob , Milleman Kimberly R. , Milleman Jeffery L. , Walsh Laurence James
Published: October 2023

Dentifrice performance in the removal of dental plaque is influenced by the interactions of dentifrice components with tooth surfaces. This randomized controlled clinical study assessed the effectiveness and safety of a novel fluoride dentifrice formulation that included a micro-fibrillated cellulose network with entangled microcrystalline cellulose and silica particles (ProtegeraTM), and compared this to a positive control fluoride dentifrice (Crest Cavity Protection™). Whole mouth dental plaque levels in 82 healthy adults were measured after the first supervised use, and following a week of twice daily use at home. Overall, the novel dentifrice was at least three times more effective in whole mouth plaque reductions than the reference dentifrice (p < 0.001), with a 38.6% reduction on first use, a 30.9% reduction at day 7, and a 41.6% reduction from day 1 to day 7, compared to reductions of 12.0%, 9.6%, and 11.6% respectively for the positive control. No safety issues arose from the use of the novel dentifrice. These results indicate that including micro-fibrillated cellulose enhances plaque removal effectiveness, without causing adverse changes to oral soft tissues.
MEF2C Directly Interacts with Pre-miRNAs and Distinct RNPs to Post-transcriptionally Regulate miR-23a-miR-27a-miR-24-2 microRNA Cluster Members Expression
Authors: Lozano-Velasco Estefanía , Garcia-Padilla Carlos , Carmona-Garcia Miguel , Gonzalez-Diaz Alba , Arequipa-Rendon Angela , Aránega Amelia Eva , Franco Diego
Published: October 2023

Transcriptional regulation constitutes a key step in gene expression regulation. Myocyte enhancer factor 2C (MEF2C) is a transcription factor of MADS box family involved in the early development of several cell types including muscle cells. Over the last decade a novel layer of complexity modulating gene regulation is emerging as non-coding RNAs have been identified, impacting in both transcriptional and post-transcriptional regulation. microRNAs represent the most studied and abundantly expressed subtype of small non-coding RNAs and their functional role have been widely documented. On the other hand, our knowledge on the transcriptional and post-transcriptional regulatory mechanisms that drive microRNA expression is still incipient. We recently demonstrated that MEF2C is able to transactive the long, but not short, regulatory element upstream of miR-23a-miR-27a-miR-24-2 transcriptional start site. However, MEF2C over-expression and silencing, respectively, displayed distinct effects on each of the miR-23a-miR-27a-miR-24-2 mature cluster members, without affecting pri-miRNA expression levels, supporting thus additional MEF2C-driven regulatory mechanisms. Within this study we demonstrated a complex post-transcriptional regulatory mechanisms directed by MEF2C in the regulation of miR-23a-miR-27a-miR-24-2 cluster members, distinctly involving different domains of the MEF2C transcription factor and the physical interaction with pre-miRNAs and RNA interacting proteins such as Ksrp, HnRNPa3 and Ddx17.
Macro-Micro Coupled Simulations of Dilute Viscoelastic Fluids
Authors: Cromer Michael , Vasquez Paula A.
Published: October 2023

Modeling the flow of polymer solutions requires knowledge at various length and time scales. The macroscopic behavior is described by the overall velocity, pressure and stress. The polymeric contribution to the stress requires knowledge of the evolution of polymer chains. In this work, we use a microscopic model, the finitely extensible nonlinear elastic (FENE) model, to capture the polymer behavior. The benefit of microscopic models is they remain faithful to the polymer dynamics without information loss via averaging. The downside is the computational cost needed to solve the thousands to millions of differential equations describing the microstructure. We thus describe a multiscale flow solver that utilizes GPUs for massively parallel, efficient simulations. We compare and contrast the microscopic model with its macroscopic counterpart under various flow conditions. In particular, significant differences are observed under nonlinear flow conditions, where the polymers become highly stretched and oriented.
Resveratrol Reduces ROS by Increasing GSH in Vitrified Sheep Embryos
Authors: González-Garzón Andrea Carolina , Ramón-Ugalde Julio Porfirio , Ambríz-García Demetrio Alonso , Vazquez-Avendaño José Roberto , Hernández-Pichardo José Ernesto , Rodríguez-Suástegui José Luis , Cortez-Romero César , Navarro-Maldonado María del Carmen
Published: October 2023

The in vitro production and cryopreservation of mammalian embryos generate reactive oxygen species (ROS) due to conditions of the system that can overcome their antioxidant protection. Resveratrol is an antioxidant used in in vitro systems improving blastocyst rates, but its effect on antioxidant enzymes such as glutathione (GSH) in embryos produced by in vitro fertilization (IVF) after vitrification has not been reported. The objective of this study was to evaluate the effect of resveratrol in the in vitro maturation medium (IVM) of sheep oocytes (Ovis aries) on the levels of ROS and GSH in embryos produced by IVF subjected to vitrification. Resveratrol was added at 0µM, 0.25µM, 0.5µM and 1µM during oocyte in vitro maturation (IVM). Matured oocytes were fertilized with thawed ram sperm. Embryos were cultured in sequential media until blastocysts, then were vitrified for 24 h and after heating they were stained with DCFH-DA (2',7'-dichlorodihydrofluorescein diacetate) to determine the presence of ROS and with Cell Tracker Blue® for the presence of GSH. The quantitative values of ROS and GSH were obtained through the Image J image processor. The results showed that resveratrol increases GSH and decreases ROS production (p<0.05). It is concluded that its use in sheep oocytes during IVM has a beneficial effect on embryos produced by IVF subjected to vitrification, protecting them from oxidative damage by promoting the synthesis of antioxidants.
Effects of Revenue-Sharing Contracts and Overconfidence on Innovation for Key Components
Authors: Wei Chengli , Chen Hongzhuan , Kang Yuanfei
Published: October 2023

Revenue-sharing (RS) contracts are a common approach to incentivize innovation of upstream suppliers by addressing the uneven profit distribution between upstream and downstream firms. Considering the possible overconfidence characterizing decision makers in the supply chain, we investigate the effect of the RS contract and the tendency of overconfidence of supply chain members on the investment in R&D of key components of products in the context of an upstream supplier that is the leader in the R&D and production of key components. We find that regardless of the bargaining power of either party, a RS contract can increase the R&D investment in key components. Regarding the effects of overconfidence of either downstream manufacturer or up-stream supplier, it can increase the R&D investment in key components. Supplier (manufacturer) overconfidence can harm their own profits but increase the profits of the manufacturer (supplier), and when the level of overconfidence is below a certain threshold, the damage to their own profits is less than the increase in each other's profits, thus benefiting the whole supply chain. In addition, we also find a joint effect of RS contracts and overconfidence: when the bargaining power of the supplier is low, the RS contract has a certain compensatory effect on the loss of their own profits caused by overconfidence.
Change in the Physiological Aspects of Soybean Caused by Infestation by Bemisia tabaci MEAM1
Authors: Silva Luciana Barboza , Almeida Lucas Costa , Silva Maria Carolina Farias , Brito Ramilos Rodrigues , Miranda Rafael Silva , Rodrigues Raimundo Henrique Ferreira , Santos Carlos MAgno , Ribeiro Gilvana da Silva , Morais João Vitor Silva , Silva Alisson Franco Torres da , Mayard Hernesise , Oliveira Thayline Rodrigues , Lima Vânia Maria Gomes da Costa , Fontes Lucia Silva , Rocha Neurandir Sobrinho , Lacerda Julian Jesus , Pavan Bruno Ettore
Published: October 2023

The whitefly leads extensive damage to plants through direct feeding, honeydew secretion, plant physiological disorders, and vectoring plant viruses. This study aimed to evaluate the physiological characteristics of susceptible and resistant soybean cultivars to B. tabaci. The experiments were conducted in a greenhouse. Eleven soybean cultivars were selected and infested with 100 adults of B. tabaci at the V3 stage. The evaluation of photosynthetic parameters, such as photosynthetic rate, leaf transpiration, stomatal conductance, and internal CO2 concentration, revealed that B. tabaci infestation influenced gas exchange in soybean plants. The photosynthetic rate was higher in cultivars AS3810 and M8349 during the V6 stage. Infestations led to alterations in photosynthetic parameters, suggesting increased energy demand to maintain photosynthetic activity. However, the response to infestation varied among different cultivars, indicating varying levels of resistance and tolerance to the whitefly's damage. Additionally, the impact of infestation was more significant during the vegetative phenological. In conclusion, B. tabaci infestation affects soybean plants' physiology, leading to changes in gas exchange parameters and water use efficiency. The response to infestation varied among soybean cultivars, suggesting potential differences in resistance to the pest. The study highlights the importance of evaluating the physiological impact of whitefly infestations on soybean.
Modulation of Apoptosis by Bovine Herpesvirus Type 4 Infection in Bovine Endometrial Cells and the Possible Role of LPS in this Process
Authors: Romeo Florencia , Delgado Santiago , Yavorsky Marisol , Martinez Cuesta Lucia , Pereyra Susana , Gonzalez Altamiranda Erika , Louge Uriarte Enrique , Perez Sandra , Verna Andrea
Published: October 2023

The prevalent pathogens associated with bovine uterine infections are bacteria that appear to increase the host's susceptibility to secondary infections with other bacteria or viruses, among which BoHV-4 is the most frequently found. In this work, the study of the pathways of apoptosis induction was carried out on an experimental model of primary culture of endometrial cells, in order to know the implication of BoHV-4 and the presence of bacterial LPS in the pathogenesis of the bovine reproductive tract. For this, different staining techniques and molecular analysis by RT-PCR were used. The results obtained allowed us to conclude that the level of cell death observed in the proposed primary culture is directly related to the time of viral infection and the presence of LPS in BoHV-4 infection. The apoptosis indices in cells infected with BoHV-4, BoHV-4 + LPS presented a maximum that correlates with the appearance of the cytopathic effect, and the maximum viral titers in the model studied. However, morphological, biochemical and molecular changes were evident during both early and late stages of apoptosis. These findings provide information on the factors that may influence the pathogenesis of BoHV-4 and help to better understand the mechanisms involved in virus infection.
H2S Removal via Sorption Process on Activated Carbon-Metal Oxide Composites Derived from Different Biomass Sources
Authors: Baikousi Maria , Gantzoudi Anna , Gioti Christina , Moschovas Dimitrios , Giannakas Aris E. , Avgeropoulos Apostolos , Salmas Constantinos E. , Karakassides Michael A.
Published: October 2023

Biomass exploitation is a global trend due to the circular economy and the environmentally friendly spirit. Numerous applications are now based on the use of biomass derived products. Hydrogen sulfide (H2S) is a highly toxic and environmentally hazardous gas, which emitted from various processes. Thus, the efficient removal of this toxic hazardous gas following cost effective processes is an essential requirement. In this study, we present the synthesis and characterization of biomass-derived activated-carbon/zinc-oxide (ZnO@AC) composites from different biomass sources as potential candidates for H2S sorption. The synthesis involved a facile method for activated carbon production via pyrolysis and chemical activation of biomass precursors (spent coffee, Aloe-Vera waste leaves, and corncob). Activated carbon production was followed by the incorporation of zinc oxide nanoparticles into the porous carbon matrix using a simple melt impregnation method. The synthesized ZnO@AC composites were characterized using X-ray diffraction (XRD), infrared spectroscopy (IR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM) and nitrogen porosimetry. The H2S removal performance of the ZnO@AC composites was evaluated through sorption experiments using a handmade apparatus. Our findings demonstrate that the Aloe-Vera, Spent-coffee, and Corncob derived composites exhibit superior H2S sorption capacity up to 106 mgH2S/gads., 66 mgH2S/gads., and 47 mgH2S/gads. respectively.
Land evaluation assessment of komombo area south Egypt using remotely sensed imagery
Authors: Elsharkawy Mohamed
Published: October 2023

Nowadays, the demand of agricultural production increase, Moreover, the rapid increase of the population in Egypt led to an increase in the demand for food, prompting the government to reclaim more desert lands. Such a study contributes to providing information that contributes to the promising optimization of land resources. This study carried out in an area south Egypt covering 386,171.04 hectares (ha). Remote sensed data were manipulated for defining the land cover/use features. Setting up DEM configures the network of natural drainage flows via the descending slopes. It was a guide for allocating micro dams as water harvesting sites as well as minimizing the runoff hazards and managing the priority of land use suitability versus flood hazards. Land cover/use units were defined as terrestrial irrigated areas of sequentially herbacous crops and permanent trees covering 1387.83 ha in levees; 1608.82 ha in point bar; 718.89 ha in bow bar and 23938.29 ha in alluvial plain. Terrestrial natural vegetation is dominated by xerophytes herbaceous in wadis (123533.56 ha). Terrestrial non-vegetated areas includes bare areas of rock land (98102.59 ha) and 67201.57 in bajada. Artificial non linear surfaces include buildings (5403.59 ha) and linear features include roads and railways (875.78 ha). Aquatic areas include artificial irrigation and drainage canals (1062.15 ha) and natural water body of River Nile course (2785.92 ha). Current land suitability for specific Land Utilization Types (LUTs) was assessed by matching soil attributes with the growth requirement of each LUT. Current land suitability can be improved by decreasing of salinity and framing practices. Accordingly, the land units can be potentially more profitable for increasing the ability of extra crops to be more productive. Old cultivated areas are the most profitable land cover/use units highly suitable (S1) for all LUTs comparing with other land cover categories.
Molecular Sexing of Wild and Companion Birds Using Samples Collected by Minimally Invasive Methods
Authors: Turcu Maria-Carmen , Paștiu Anamaria Ioana , Bel Lucia Victoria , Pusta Dana Liana
Published: October 2023

Birds are highly social and need pairing in order to increase their welfare. Most bird species are monomorphic, therefore, molecular sexing helps to provide appropriate welfare for birds. Moreover, early sex determination can be of great value for bird owners. The aim of this study was to demonstrate that sex identification in birds by molecular methods, using samples collected by minimally invasive methods is fast, efficient and accurate. A total of 100 samples (29 paired samples of feathers - oral swab and 14 tripled samples of feathers - oral swab - blood) from 43 birds were taken into study, as follows: wild birds (Falconiformes, Accipitriformes, landfowl – Galliformes, waterfowl– Anseriformes), companion birds (Passeriformes, Psittaciformes – large, medium and small size parrots). Amplification of CHD1-Z and CHD1-W genes was performed by conventional PCR. The results obtained from feathers were compared to those obtained from oral swabs and with those obtained from blood samples, where was the case. The obtained results show that all types of samples can be used for molecular sexing of all studied species of birds. According to our knowledge, the present study reports for the first time the molecular sex identification in: Red Siskin (Carduelis cucullata) and Goldfinch (Carduelis carduelis major). For higher accuracy, our recommendation is to use minimally invasive samples (swab-feathers) and to test both types of samples, for each bird, instead of blood samples.
A Long-Term Monitoring Survey of Diplectanum aequans, Parasite of the European Cultured Sea Bass Dicentrarchus labrax (Linnaeus 1758) (Pisces: Teleostei) From Corsican Fish Farms
Authors: MASALA-ANTONELLI Laetitia , GODEAUX Quentin , POIRON-GUIDONI Nicolas , BISGAMBIGLIA Paul-Antoine , QUILICHINI Yann
Published: October 2023

This work focused on Diplectanum aequans, a gill parasite of Dicentrarchus labrax. Analyzes allowed us to detect factors regulating parasites distribution on Corsican fish-farms, and to highlight the ecological structure of D. aequans communities on gills of fish. The study of parasite distribution showed that bigger fish appear more parasitized and that the infection dynamics of D. aequans can be explained by several factors such as biotic factors or farm environment conditions. The study of gill repartition of D. aequans showed that parasites tend to have a homogeneous distribution with no statistically significant difference in infection between two sides on each fish. However, the distribution of the number of parasites on gill arches varies according to the total number of parasites. Results differ depending on infection degree and host weight. When parasites are numerous, the individuals are distributed on the gill arches according to an antero-posterior gradient, while with low rates of infection, the parasites are randomly distributed on the 4 arches. The spatial distribution of D. aequans appears to be determined by the differential action of water flow through gill arch and the size of anterior arches. We also proposed a tool in order to reduce the sampling effort and allow optimal exploitation for fish farmers.
Tracking the route walked by Missing Persons and Fugitives: A Geoforensics casework (Italy)
Authors: Somma Roberta
Published: October 2023

Criminal investigations aimed to track the route walked by Missing Persons and Fugitives (MPFs) usually involve Intelligence analysts, military planners, experts in mobile forensics, traditional investigative methods, and sniffer dog handlers. Notwithstanding, when MPFs are devoid of any technological device and move in uninhabited rural areas devoid of tele cameras and densely covered by vegetation, tracking backwards the route walked by MPFs may be a much more arduous task. In such complex cases, a very efficient approach may consist in comparing the geological traces found on the MPFs with soils and plants exposed in the event scenes. In particular, the search for peculiar or rare particles and aggregates may strengthen the weight of the geological evidence comparisons. A match of mineralogical, textural, and botanical data may demonstrate the provenance of the traces from the soil of a specific site, linking in this way the MPFs to the scene of events. Based on the above, the present paper reports geological and botanical determinations accomplished for a “mediatic” casework. Results allowed to ascertain a general high degree of compatibility among traces collected on the MPFs and on the soil from the scene of events. The most significant positive matches, based on the finding of a ten of peculiar and rare particles and assemblages, allowed reconstructing a route about 1.1 km long, as the crow flies, on the event site. Notwithstanding this procedure was extremely time consuming and available only in a backwards reconstruction linked to the MPFs’ findings, it was of uttermost importance in strengthen the inferences proposed, where other methods could not provide any information.
Insights into the Brain Effects of a Bacterial Nicotine Derivative – 6-Hydroxy-L-Nicotine
Authors: Boiangiu Razvan Stefan , Brinza Ion , Honceriu Iasmina , Mihasan Marius , Hritcu Lucian
Published: October 2023

The purported cognitive benefits associated with nicotine and its metabolites in the brain are a matter of debate. In this review, the impact of the pharmacologically active metabolite of a nicotine derivative produced by bacteria (6-hydroxy-L-nicotine) on memory, oxidative stress, and the activity of the cholinergic system in the brain was examined. A search in the PubMed, Science Direct, Web of Science, and Google Scholar databases, limiting entries to those no later than July 2023, was conducted. The search focused specifically on articles pertaining to nicotine metabolites, memory, oxidative stress, cholinergic system activity, as well as enzymes or pathways related to nicotine degradation in bacteria. The preliminary search resulted in 696 articles, and following the application of exclusion criteria, 185 articles were deemed eligible for inclusion. This review focuses on experimental studies supporting nicotine catabolism in bacteria, and the chemical and pharmacological activities of nicotine and its metabolite 6-hydroxy-L-nicotine.
A New Solution to the Strong CP Problem
Authors: Larin Sergey
Published: October 2023

We suggest a new solution to the strong CP problem. The solution is based on the proper use of the boundary conditions for the QCD generating functional integral. It obeys the principle of renormalizability of Quantum Field Theory and does not involve new particles like axions.
Capital Asset Pricing Model 2.0: Account of Business and Financial Risk
Authors: BRUSOV PETR , Filatova Tatiana , Kulik Veniamin
Published: October 2023

The famous Capital Asset Pricing Model (CAPM) takes into account only business risk. In practice, companies use debt financing and operate at non–zero levels of leverage. This means that it is necessary to take into account the financial risk associated with the use of debt financing along with business one. The purpose of this paper is to simultaneously take into account the business and financial risk. A new approach to CAPM has been developed that takes into account both business and financial risk. We combine the theory of CAPM and the Modigliani–Miller (MM) theory. The first is based on portfolio analysis and accounting for business risks in relation to the market (or industry). The second one (the Modigliani–Miller (MM) theory) describes a specific company and takes into account the financial risks associated with the use of debt financing. The combination of these two different approaches makes it possible to take into account both types of risks: business and financial ones. We combine these two approaches analytically, while Hamada did it phenomenologically. Using the Modigliani–Miller (MM) theory, it is shown that the Hamada’s model, first model, used for this purpose half a century ago, is incorrect. In addition to the renormalization of the beta–coefficient, obtained in the Hamada model, two additional terms are found: the renormalized risk–free return and the term dependent on the cost of debt kd. A critical analysis of the Hamada model was carried out. The vast majority of listing companies use debt financing and are levered, and the Hamada model is not applicable to them in contrast to a new approach applicable to leveraged companies. Implemented a new approach to specific companies. A comparison of the results of the new approach with the results of the conventional CAPM is shown. Two versions of CAPM (market or industry) are considered.
Estimates for Approximation and Eigenvalues of the Resolvent of a Class of Singular Operators of Parabolic Type
Authors: Muratbekov Mussakan , Muratbekov Madi , Igissinov Sabit , Igissinova Zhazira
Published: October 2023

In this paper, we study a differential operator of parabolic type with a variable and unbounded coefficient, defined on an infinite strip. Sufficient conditions for the existence and compactness of the resolvent are established, and an estimate for the maximum regularity of solutions of the equation Lu=f∈L_2(Ω) is obtained. Two-sided estimates for the distribution function of approximation numbers are obtained. As is known, estimates of approximation numbers show the rate of best approximation of the resolvent of an operator by finite-dimensional operators. The paper proves the assertion about the existence of positive eigenvalues among the eigenvalues of the given operator and finds two-sided estimates for them.
A Brief Case Report on Umbilical Cord Connective Tissue Allograft Application for Defects of the Achilles Tendon
Authors: Parker Robert , Shou John , Lambert Naomi , Woods Crislyn , Barrett And Tyler
Published: October 2023

Damaged connective tissues between the bone and tendons or ligaments are common among adults regardless of activity level. Achilles tendinosis is one of the most common tissue defects and enthesopathies. The patient in this study is a 54-year-old female with chronic Achilles tendinosis from chronic enthesopathy at the Achilles tendon insertion with a retrocalcaneal exostosis for three years who has failed standard-of-care practices for over two years. The patient received extracorporeal pulsed-activated therapy (EPAT) before applying 2ml of CryoText, a Wharton’s jelly tissue allograft. The patient then received class IV laser therapy treatments twice weekly for three weeks. The patient started with a 10/10 VAS at the initial visit. At five weeks post-application, the patient’s score had improved by 80% at 2/10 VAS. By week 13, the patient rated her pain as 0/10 VAS. The improvement in patient-reported pain and functionality reported in this study after the application of Wharton’s Jelly, EPAT, and class IV laser therapy warrants future research studying the safety and efficacy of these patient care modalities together.
Content and Yield of L-DOPA and Bioactive Compounds of Broad Bean Plants: Antioxidant and Anti-Inflammatory Activity In Vitro
Authors: Fuentes-Herrera Paula Beatriz , Herrera-Cabrera Braulio Edgar , Martínez-Ayala Alma Leticia , Zamilpa Alejandro , Delgado-Alvarado Adriana
Published: October 2023

The broad bean plant contains L-DOPA, a compound that is essential for patients with Parkin-son’s disease. However, little has been reported on other broad bean compounds that have bene-ficial effects on health. The objective was to evaluate plants of four Mexican broad bean varieties to determine the content and yield of total phenolic compounds (TPC), total flavonoids (TF), and L-DOPA, as well as to analyze the flavonoid profile and antioxidant (AA) and anti-inflammatory (AANTI) activity in vitro. Broad bean seeds were sown in the field and plants were harvested 20 days after emergence. The analyses were performed with visible UV spectrophotometry and HPLC. The variety José María produced the highest yield of TPC (9.30 g m-2), TF (8.08 g m-2) and L-DOPA (5.64 g m-2) per unit of area. The highest yields per plant were obtained with the Rojita variety: TPC (0.25 g plant-1), TF (0.21 g plant-1) and L-DOPA (0.17 g plant-1). This variety also had the highest antioxidant (CI50= 87.68 µg mL-¹) and anti-inflammatory (CI50= 74.40 mg mL-1) activi-ty, which was attributed to the L-DOPA compounds and to rutin and isoorientins, respectively. The flavonoid profile revealed the presence of rutin and isoorientins, which had not been previ-ously detected in the broad bean plant.
Online Machine Learning and Surrogate Model-Based Optimization for Improved Production Processes Using a Cognitive Architecture
Authors: Hinterleitner Alexander , Schulz Richard , Hans Lukas , Subbotin Aleksandr , Barthel Nils , Pütz Noah , Rosellen Martin , Bartz-Beielstein Thomas , Geng Christoph , Priss Phillip
Published: October 2023

Cyber-Physical Systems (CPS) play an essential role in today’s production processes, leveraging Artificial Intelligence (AI) to enhance operations such as optimization, anomaly detection, and predictive maintenance. This article reviews a cognitive architecture for artificial intelligence, which has been developed to establish a standard framework for integrating AI solutions into existing production processes. Given that machines in these processes continuously generate large streams of data, Online Machine Learning (OML) was identified as a crucial extension to the existing architecture. To substantiate this claim, real-world experiments using a slitting machine were conducted to compare the performance of OML with traditional Batch Machine Learning. The evaluations clearly indicate that OML adds significant value to CPS and is strongly recommeded as an extension of related architectures such as the cognitive architecture for AI discussed in this article. Additionally, surrogate model-based optimization is employed to determine the optimal hyperparameter settings for the corresponding OML algorithms, aiming to achieve peak performance in their respective tasks.
Innovative Leadership in Addressing Climate Change: A Pathway towards Sustainable Futures
Authors: Moleka Pitshou
Published: October 2023

This article explores the intersection of innovative leadership and climate change, aiming to provide outstanding contributions to the existing body of knowledge in this field. The article identifies the critical role of innovative leadership in driving sustainable solutions and strategies for addressing climate change. It examines the defining characteristics and behaviors of innovative leaders and explores how their transformative leadership approaches can create a positive impact on climate change mitigation and adaptation efforts. The article also highlights the importance of fostering innovation within organizations and societies to tackle the complex challenges posed by climate change. Through a comprehensive review of relevant literature and case studies, this article presents novel insights, theoretical frameworks, and practical implications for policymakers, organizations, and individuals involved in climate change leadership.
The Distinct Absence of a Post-boost Spike-IgG Antibody Surge in Ugandan Recipients of the Pfizer-BioNTech Vaccine Has Implications for Vaccination Policies
Authors: Serwanga Jennifer , Ankunda Violet , Katende Joseph Ssebwana , Sembera Jackson , Oluka Gerald Kevin , Baine Claire , Odoch Geoffrey , Ejou Peter , Kato Laban , Kaleebu Pontiano
Published: October 2023

This study aimed to delineate the longitudinal antibody responses to the Pfizer- BioNTech COVID-19 vaccine (BNT162b2) within the Ugandan subset of the Sub-Saharan African (SSA) demographic, filling a significant gap in global datasets. We enrolled 48 participants, collecting 320 specimens over 12 months after vaccination. A validated enzyme-linked immunosorbent assay (ELISA) was used to quantify SARS-CoV-2-specific IgG, IgM, and IgA concentrations (ng/ml) and optical densities (ODs). Statistical analyses included box plots, diverging bar graphs, and the Wilcoxon test with Bonferroni correction. We showed a robust SIgG response within 14 days of the primary vaccine dose, consistent with global data. Remarkably, we observed no significant surge in S-IgG levels following the booster, contrasting trends other global populations. The S-IgM response was transient, and predominantly established thresholds, reflecting its typical early emergence and subsequent decline. S-IgA increased initially but declined six months post-vaccination, in line with the temporal dynamics of mucosal immunity. Eleven breakthrough infections occurred; however, all were asymptomatic, indicating a protective effect from the vaccination regardless of the participants' initial S-IgG serostatus. The Pfizer-BioNTech COVID-19 vaccine elicited strong S-IgG responses in the SSA demographic. However, antibody dynamics distinctly differed from global data highlight the significance of region-specific research and the necessity for customized vaccination strategies.
On the fractional derivative duality in some transforms
Authors: Ortigueira Manuel Duarte , Bengochea Gabriel
Published: October 2023

The duality is one of the most interesting properties of the Laplace and Fourier transforms associated to the integer order derivative. Here, we will generalize it for fractional derivatives and extend the results to the Mellin, Z and discrete-time Fourier transforms. The scale and nabla derivatives are used.
Exhaustive Computational Studies on Pyrimidine Derivatives as GPR119 agonist for the Development of Compounds against NIDDM
Authors: Nema Priyanshu , Agarwal Shivangi , Kori Shivam Kumar , Kumar Ajay , Kashaw Varsha , Soni Vandana , Iyer Arun K , Kashaw Sushil Kumar
Published: October 2023

(1) Background: Type-2 Diabetes (T2DM) is a long-term medical disorder characterized by Insulin deficiency and high blood glucose levels. Among other medication to cure T2DM, the review of the literature found that various Pyrimidine derivative act as an agonist for G-protein-coupled receptor 119 (GPR119) was proposed to control blood glucose levels by enhancing the function of pancreatic beta-cells and its mechanism of action with fewer adverse effects.; (2) Methods: In the present research work, in-silico investigations were carried out to investigate the potential of Pyrimidine analogue as an agonists to the protein target GPR119 receptor. We performed exhaustive molecular modelling and protein modelling methodologies such as homology mod-elling, molecular docking along with various drug designing tools such as 3D-QSAR and pharmacophore mapping to ascertain the design of better GPR119 agonists.; (3) Results: On the basis of in-depth computa-tional studies, we designed new pyrimidine moiety and analyzed them for GPR-119 receptor agonist and fur-ther explored the ADME properties. Designed compounds found to exhibit better predicted activities as com-pared to reference compound; (4) Conclusions: The current research on pyrimidine derivatives, using molec-ular docking, 3D-QSAR and Pharmacophore mapping demonstrated that the obtained computational model has significant properties and the designed molecules and Dataset from this model, produced antidiabetic compound against the target GPR119 i.e., compound 1S, 1Z and 1D with the docking score of −11.696, -9.314 and -8.721 respectively. The pharmacokinetics and drug-likeness studies revealed that these compounds may be the future candidate for the treatment of diabetes acting via GPR119 agonist mechanism.