bluuebunny/crossref_metadata_2025 huggingface dataset:
Biosynthesis and FPLC purification of antibacterial peptide from the biotherapeutic agent Enterococcus faecium
Authors: Abd-Elwahed Eslam S. , El-Waseif Amr A. , Maany Dina A.
Published: June 2023

Background

Probiotics are microorganisms that play an essential role in microbial intestinal balance and in health care.

Objective

To isolate a probiotic that can be used to produce antimicrobial peptides potentially used as inhibitors against pathogenic bacteria.

Materials and methods

The research protocol was carried out through isolation of samples from different dairy product and screening for the most potent probiotic exhibiting antimicrobial activity against Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC 8739 according to the guidelines of Clinical and Laboratory Standards Institute using the disc diffusion method. The molecular identification of this probiotic strain was done by 16S ribosomal DNA sequencing, and the phylogenetic tree was obtained. The purification process and characterization of the antibacterial peptide were done by (NH4)2SO4 and performing fast protein liquid chromatography.

Results and discussion

Bacterial probiotic strains obtained from different samples were screened for the best antimicrobial activity, where isolate number 9 from 18 isolates showed the highest antibacterial activity against S. aureus and E. coli. Therefore, it was chosen for molecular identification. The molecular identification process revealed that isolate number 9 was Enterococcus faecium. Results of antibiotics sensitivity indicated that S. aureus is more sensitive to antibiotics than E. coli. The fast protein liquid chromatography purification and characterization process of the peptide produced from the probiotic E. faecium showed that the active fraction was precipitated at 60% saturation of (NH4)2SO4. Moreover, single absorbance peaks confirmed the presence of the peptide ‘enterocin.’
Serratus anterior plane block versus intravenous opioid use for acute post-thoracotomy pain
Authors: Badawy Fawzy Abbas , El-Rahman Abd El-Rahman Hassan Abd , Hassan Khaled M. , Farghaly Gad-Allah Asmaa Saad-Eldeen , Abdelfattah Khaled A.M.
Published: June 2023

Background

Inadequate treatment of post-thoracotomy pain can lead to both acute impact on patient comfort and pulmonary function, and long-term pain interfering with patients’ regular activities for a long time. This study aimed to evaluate the analgesic effectiveness of serratus anterior plane block (SAPB) as a regional analgesic procedure in post-thoracotomy pain.

Patients and methods

In this randomized, prospective, interventional, single-center, and double-blind study, patients were randomly assigned into two groups of 30 patients each. Group A: patients were subjected to standard anesthesia and ultrasound-guided SAPB using 30 ml of 0.25% bupivacaine after induction of anesthesia. In addition, rescue postoperative intravenous opioid analgesia was used when needed to maintain the visual analog scale (VAS) at less than or equal to 3.Group B: standard anesthesia was done, and titrated postoperative intravenous opioid analgesia was used for post-thoracotomy pain relief to maintain the VAS at less than or equal to 3.

Our primary outcome was to measure postoperative VAS at rest and on coughing up to 24 h postoperatively. Our secondary outcomes were to measure total intraoperative and postoperative opioid used, to record opioid use over time intervals, time to first postoperative opioid administration, and to assess opioid-related complications, all up to 24 h postoperatively.

Results

VAS at rest and on coughing up to 6 h postoperatively was significantly less in the SAPB group, and there was no significant difference between both groups from 6 h up to 24 h postoperatively. Total intravenous opioids used, total intraoperative fentanyl, total postoperative morphine, and time-related postoperative morphine up to 6 h postoperatively were significantly less in the SAPB group, and there was no significant difference between both groups from 6 up to 24 h postoperatively. The time to first postoperative opioid use was also significantly longer in the SAPB group.

Conclusion

Ultrasound-guided SAPB can be an effective technique for post-thoracotomy analgesia with probably better pain control compared with intravenous opioid analgesia alone, with less total opioid use.
Ultrasound-guided continuous erector spinae plane block for perioperative opioid sparing analgesia in breast cancer surgery: A randomized controlled trial
Authors: Bajpai Shalini , Kumar K. Shiv , Patibandla Swetha , Giridhar C. M.
Published: June 2023

Background:

Erector spinae plane (ESP) block provides postoperative analgesia in breast surgeries but has limited duration of action that restricts its efficacy to early postoperative period. This study aims to evaluate the analgesic efficacy and opioid sparing effect of ultrasound (US)-guided continuous erector spinae plane (CESP) block in perioperative period in breast cancer surgery.

Methods:

Fifty ASA I/II patients aged more than 18 years, scheduled for elective breast cancer surgery were randomized to either Group B (Block group) or Group C (Control group). Patients in group B received US-guided CESP block, whereas patients in group C did not receive the block prior to general anesthesia. The primary outcome of this study was to measure total tramadol consumption in 24 h postsurgery. Intraoperative fentanyl consumption, pain scores, postoperative nausea/vomiting, and patient satisfaction score at discharge were also recorded.

Results:

Total tramadol consumption was 94.6% lower in the block group as compared to the control group (5.4 ± 18.7 mg in CESP block group as compared to 99.7 ± 49.6 mg in control group). Intraoperative fentanyl requirement and pain scores were significantly lower in CESP group. Postoperative incidence of nausea/vomiting was similar, but satisfaction score was significantly better in block group.

Conclusion:

US-guided CESP block provides effective and prolonged peri operative analgesia and opioid sparing in breast cancer surgeries.
An Assessment of Factors Influencing University Students' Intentions to Purchase Luxury Skincare Products
Authors: Monika  , Kapoor Deepa , Gupta Priya
Published: June 2023

This study explores the consumer behavior of university students in the Delhi-NCR region toward purchasing luxury skin care products, focusing on the impact of vanity, brand equity, brand loyalty, brand awareness, and perceived quality on their purchase intention. The rapid growth of the luxury skincare market in India, coupled with the increased spending power and influence of the younger generation, makes it vital to understand the factors driving their purchasing decisions. A quantitative research methodology was employed, using a structured questionnaire to collect data from 200 university students in the Delhi-NCR region. SEM and multiple regression analysis examined the relationships between vanity, brand equity, brand awareness, brand loyalty, perceived quality, and purchase intention. The findings of this study reveal that all independent variables significantly influence the purchase intention of luxury skincare products among university students in the Delhi-NCR region. Vanity emerged as the most influential factor, followed by brand loyalty, perceived quality, brand equity, and brand awareness. This suggests that in addition to the functional benefits of luxury skin care products, social and emotional aspects play a critical role in shaping the purchase intentions of university students. This research has practical implications for marketers and luxury skincare brands targeting youth, particularly in product development, branding, and promotional strategies. By understanding the role of each factor in driving purchase intention, brands can tailor their marketing efforts to enhance brand equity, raise awareness, foster loyalty, build strong brands, and communicate the high quality of their products, ultimately increasing their market share in the competitive luxury skincare market.
Lazertinib versus Gefitinib as First-Line Treatment for EGFR-mutated Locally Advanced or Metastatic NSCLC: LASER301 Korean Subset
Authors: Lee Ki Hyeong , Cho Byoung Chul , Ahn Myung-Ju , Lee Yun-Gyoo , Lee Youngjoo , Lee Jong-Seok , Kim Joo-Hang , Min Young Joo , Lee Gyeong-Won , Lee Sung Sook , Lee Kyung-Hee , Ko Yoon Ho , Shim Byoung Yong , Kim Sang-We , Shin Sang Won , Choi Jin-Hyuk , Kim Dong-Wan , Cho Eun Kyung , Park Keon Uk , Kim Jin-Soo , Chun Sang Hoon , Wang Jangyoung , Choi SeokYoung , Kang Jin Hyoung
Published: June 2023

Purpose This subgroup analysis of the Korean subset of patients in the phase 3 LASER301 trial evaluated the efficacy and safety of lazertinib versus gefitinib as first-line therapy for epidermal growth factor receptor mutated (EGFRm) non–small cell lung cancer (NSCLC).Materials and Methods Patients with locally advanced or metastatic EGFRm NSCLC were randomized 1:1 to lazertinib (240 mg/day) or gefitinib (250 mg/day). The primary endpoint was investigator-assessed progression-free survival (PFS).Results In total, 172 Korean patients were enrolled (lazertinib, n=87; gefitinib, n=85). Baseline characteristics were balanced between the treatment groups. One-third of patients had brain metastases (BM) at baseline. Median PFS was 20.8 months (95% confidence interval [CI], 16.7 to 26.1) for lazertinib and 9.6 months (95% CI, 8.2 to 12.3) for gefitinib (hazard ratio [HR], 0.41; 95% CI, 0.28 to 0.60). This was supported by PFS analysis based on blinded independent central review. Significant PFS benefit with lazertinib was consistently observed across predefined subgroups, including patients with BM (HR, 0.28; 95% CI, 0.15 to 0.53) and those with L858R mutations (HR, 0.36; 95% CI, 0.20 to 0.63). Lazertinib safety data were consistent with its previously reported safety profile. Common adverse events (AEs) in both groups included rash, pruritus, and diarrhoea. Numerically fewer severe AEs and severe treatment–related AEs occurred with lazertinib than gefitinib.Conclusion Consistent with results for the overall LASER301 population, this analysis showed significant PFS benefit with lazertinib versus gefitinib with comparable safety in Korean patients with untreated EGFRm NSCLC, supporting lazertinib as a new potential treatment option for this patient population.
Ring-theoretic blowing down II: Birational transformations
Authors: Rogalski Daniel , Sierra Susan , Stafford J. Toby
Published: June 2023

One of the major open problems in noncommutative algebraic geometry is the classification of noncommutative projective surfaces (or, slightly more generally, of noetherian connected graded domains of Gelfand-Kirillov dimension 3). Earlier work of the authors classified the connected graded noetherian subalgebras of Sklyanin algebras using a noncommutative analogue of blowing up. In a companion paper the authors also described a noncommutative version of blowing down and, for example, gave a noncommutative analogue of Castelnuovo's classic theorem that lines of self-intersection (-1) on a smooth surface can be contracted. In this paper we will use these techniques to construct explicit birational transformations between various noncommutative surfaces containing an elliptic curve. Notably we show that Van den Bergh's quadrics can be obtained from the Sklyanin algebra by suitably blowing up and down, and we also provide a noncommutative analogue of the classical Cremona transform.
Self-preferencing in the EU: a legal and policy analysis of the Google Shopping case and the Digital Markets Act
Authors: Petrucci Carlo F.
Published: June 2023

This article discusses the EU General Court’s Google Shopping judgment (Case T-612/17), which deals with online self-preferencing. Self-preferencing is a novel abuse of dominant position (Article 102 TFEU), which consists of the prominent display and positioning of the dominant undertaking’s own service (comparison shopping service in this case), and demotion of the competitors’ services, on webpages generated by the dominant undertaking’s general search services. The key-principles in the legal reasoning of the General Court’s ruling were the prohibition of discrimination and coterminous concepts such as ‘equal opportunities to compete’ and ‘competition on the merits’. The differential treatment between Google’s own service and those of its competitors derived from Google’s subjection of its adjustment algorithms only to its competitors and not to its own service. While an approach based on non-discrimination is contentious, on the other hand Google’s conduct was neither efficient nor did it benefit consumers. The article also examines the EU Digital Markets Act’s prohibition of self-preferencing and its relationship with the Google Shopping ruling.
Five phototrophic Scrippsiella species lacking mixotrophic ability and the extended prey spectrum of Scrippsiella acuminata (Thoracosphaerales, Dinophyceae)
Authors: You Ji Hyun , Ok Jin Hee , Kang Hee Chang , Park Sang Ah , Eom Se Hee , Jeong Hae Jin
Published: June 2023

Mixotrophic dinoflagellates act as primary producers, prey, and predators in marine planktonic food webs, whereas exclusively autotrophic dinoflagellates are primary producers and prey. Species of the dinoflagellate genus Scrippsiella are commonly found in marine ecosystems and sometimes cause harmful red tides. Among the 28 formally described Scrippsiella species, S. acuminata has been found to be mixotrophic and two unidentified species have been found to be mixotrophic. To determine whether the other species in this genus are similarly mixotrophic, the mixotrophic ability of S. donghaiensis SDGJ1703, S. lachrymosa SLBS1703, S. masanensis SSMS0908, S. plana SSSH1009A, and S. ramonii VGO1053 was explored using 15 potential prey items, including 2-µm fluorescently labeled microspheres (FLM) and heterotrophic bacteria (FLB), the cyanobacterium Synechococcus sp., and various microalgal prey species. The ability of S. acuminata to feed on FLM and FLB was also investigated. We found that S. donghaiensis, S. lachrymosa, S. masanensis, S. plana, and S. ramonii did not feed on any potential prey tested in this study, indicating a lack of mixotrophy. However, S. acuminata fed on both FLM and FLB, confirming its mixotrophic ability. These results lowered the proportion of mixotrophic species relative to the total number of tested Scrippsiella species for mixotrophy from 100% to 29–38%. Owing to its mixotrophic ability, S. acuminata occupies an ecological niche that is distinct from that of S. donghaiensis, S. lachrymosa, S. masanensis, S. plana, and S. ramonii.
Open Educational Resource Textbooks and Teacher Education: A Descriptive Analysis of Student in Language/Literacy Development Courses
Authors: Rutter Amanda , Black David , Ali Saadia , Berg Margaret A.
Published: June 2023

This study examines Teacher Education students’ perceptions of Open Education Resources (OER), specifically, textbooks in language/literacy courses. Participants in the study are two-hundred and eleven pre-service teachers and undergraduate students at a university in the western United States that admits 46% first-generation college students. The pre-service teachers completed a pre-survey about OER, studied in language/literacy courses using an Open Textbook (OTB), and completed a post-survey about their use of OER in the courses. Over the past two decades, the advantages and disadvantages of utilizing OER have been explored in research. Yet, there is a lack of research pertaining to language/literacy development courses in Teacher Education programs. Key findings of this study indicate that utilizing OER is new for many of the participants, the OTBs did assist them financially, and though some students chose not to read the text, the perceptions of OER were positive. The conclusion includes possible areas for future study.
The Impact of COVID-19 Pandemic on Primary, Secondary, and K-12 Education: A Systematic Review
Authors: Lampropoulos Georgios , Admiraal Wilfried
Published: June 2023

The study aims to provide a cohesive overview and summary of the COVID-19 pandemic impact on primary education, secondary education, and K-12 education through an extensive literature review. The review focused on global educational stakeholders’ perspectives, attitudes, sentiments, opinions, and experiences. This study includes and analyzes 205 articles published from January 2020 to December 2022. The scientific databases SCOPUS and Web of Science were used. Specifically, the 15 research questions to be addressed and the methodology are presented. An in-depth synthesis of the related studies is provided based on the educational level and educational stakeholders’ type. The results of the data extracted from the articles (e.g., main findings, aims, focus group, research method, sample, measurement-research tools, etc.) are examined. The findings are summarized, discussed, and compared to those of previous review articles about online learning prior to the COVID-19 pandemic. Conclusive statements, implications, and future research directions are also provided.
Unlocking the Potential of Global Learning: The Impact of Virtual Exchange Programs on Self-Efficacy
Authors: Pearl Mona , Tzoumis Kelly , Lockie Bridget
Published: June 2023

Global virtual teams (GVT) have emerged as a valuable model for facilitating virtual exchange (VE) in business and educational settings. A comprehensive four-year longitudinal study spanning from 2018 to 2021 investigated a model of self-efficacy that include discernment, resourcefulness, diverse options, creative thinking, fairness, emotional regulation, and culture. Our sample consisted of participants surveyed before the GVT experience (n=584) and after the GVT experience (n=399), representing learners from six countries. The results of the study unveiled several key findings: (a) self-efficacy was influenced by multiple factors, with fairness emerging as a more significant contributor after the GVT experience; (b) irrespective of the GVT experience, learners from individualist countries demonstrated higher levels of self-efficacy compared to those from collectivist countries, suggesting that cultural dimensions play a role in shaping learners' self-efficacy, regardless of their participation in GVT activities; and (c) when controlling for the pandemic, there was a specific impact to the learner as it related to self-efficacy and the experience of global learning. These insights contribute to our understanding of the intricate dynamics of self-efficacy in the realm of virtual exchange and provide valuable implications for educators, organizations, and policymakers seeking to enhance learner outcomes in global virtual team settings.
Is Trawl Fishery on the Verge of Collapse in Foça, Türkiye, Eastern Mediterranean?
Authors: ÜNAL Vahdet , ÖNDES Fikret
Published: June 2023

In this study, we aimed to examine the status and historical change of trawl fishing fleet in the Foça in the Aegean Sea. The data of the study representing all actively working trawlers in 1998-1999 and 2019 were collected through face-to-face interviews with trawler boat owners in Foca. The questionnaire consisted of questions related to the characteristics of the vessels, fishing activity, socio-demographics of fishers, running costs, annual landings of species and management issues. The study indicated that the annual landings of the main target species significantly decreased over the last two decades. Fishers reported the landings of some species including Dentex gibbosus, Dentex macrophthalmus, Homarus gammarus, Mustelus mustelus, Octopus vulgaris, Parapenaus longirostris, Scomber colias, Scorpaena porcus, Scorpaena scrofa, Spicara smaris, Trachurus spp. and Zeus faber decreased considerably over this period. Over the same period, a decrease was found in the mean length of Merluccius merluccius, Lophius piscatorius and Zeus faber. The vessels’ fuel tank volume and tow duration showed significant increases from 1999 to 2019. The trawl fleet decreased by ~75% from 1999 to 2019 and 55% of the current fishers reported that they may leave the fishery sector within the next 10 years. A change was also determined in the tradition of the sharing system, which is the number of crews paid in shares rather than a fixed salary, significantly decreased. Moreover, the crew numbers from vessel owners’ households significantly decreased. As a result, we discussed the changes, problems, regulations and restrictions related to trawl fishery in Foça, which used to be the most important trawling fishing center of the Aegean twenty years ago. We found dramatic changes in many aspects compared to what it was two decades ago and provided suggestions regarding fisheries management.
Population Dynamics of Seabreams (Pagrus caeruleostictus, Pagellus bellottii, Dentex angolensis and Dentex congoensis) from the Coast of Ghana, West Africa
Authors: AMPONSAH Samuel , ASİEDU Berchie , AMARQUAYE Nii Commey , OFORİ-BOATENG Emmanuel , AFRANEWAA Nana Ama , HENNEH Samuel
Published: June 2023

Stock assessment indicators of Pagrus caeruloestictus, Pagellus bellotti, Dentex angolensis and Dentex congoensis from Ghana’s coastal waters were estimated between July 2018 and June 2019. Total length measurements of 2489 samples were collected from some selected coastal communities along the Greater Accra region of Ghana and analyzed using FISAT II Tool. The asymptotic length (L∞) for P. caeruleostictus, P. bellottii, D. angolensis and D. congoensis was 39.9 cm, 31.5 cm, 31.5 cm and 28.4 cm, respectively. The growth rate (K) was 0.18 yr-1 for P. caeruleostictus, 0.36 yr-1 for P. bellottii, 0.75 yr-1 for D. angolensis and 0.83 yr-1 for D. congoensis. The current exploitation rate (E) for P. caeruloestictus, P. bellotti, D. angolensis and D. congoensis was above the optimum level of 0.5, indicating that these species are facing high fishing pressure. To ensure sustainable management of the overexploited fish species, the need for relevant management measures such extension of the closed fishing season, reduced fishing effort and others are urgently required.
Dondurarak Depolanan Balık Kıymasının Stabilizasyonu
Authors: TOLASA YILMAZ Şebnem
Published: June 2023

Günümüzde, Türkiye’de ve dünya genelinde ıskarta ve ekonomik olmayan türler, bunun yanında işleme esnasında ortaya çıkan yan ürünler, insan sağlığı açısından çok faydalı protein, yağ asitleri, vitamin ve mineralleri içermektedir. İnsan gıdası olarak yeterince etkin bir şekilde değerlendirilemeyen bu stokların, soğuk şokuna karşı dayanıklı hale getirilmiş (kriyostabilize edilmiş) kıyma blokları halinde, yenilikçi formülasyon stratejileri ile fonksiyonel gıda olarak değerlendirilmeleri mümkün olmaktadır. Ancak özellikle dondurarak depolama esnasında lipidlerin ve proteinlerin oksidasyonu kalite kayıplarına neden olmaktadır. Antioksidanlar lipid oksidasyonunun engellenmesinde, kriyoprotektanlar ise, protein denatürasyonunun geciktirilmesinde yaygın olarak kullanılmaktadır. Sentetik katkı maddelerinin olası toksisite ve karsinojenik etkilerinden dolayı, doğal içeriklerin kullanılmasına yönelik ilgi her geçen gün artmaktadır. Bu nedenle antioksidatif ve kriyoprotektif etkiye sahip içeriklerle işlenen balık kıymasının dondurarak depolamadaki kararlığı önem arz etmektedir.
Adulteration of Food Ingredient Detection Using Deep Learning
Authors: Mammoo Jubaira , Chacko Shanty
Published: June 2023

Every living thing on the planet requires food as a basic necessity. Food contains a range of nutrients, including carbohydrates, fats, minerals, and vitamins. All substances aid in the human being’s ability to live in the world healthily. Adulteration of food ingredients is a phenomenon prevalent today. To make the food supplies last for a long period and maintain freshness, merchants add several dangerous chemicals. Adulteration is the addition of undesired chemicals, the use of illegal medicines in food and other products, as well as the removal of nutrients from the original food substances. Food adulteration is defined as the deliberate lowering of food quality through the addition or substitution of a useful but inferior ingredient. Adulterated food is unclean, dangerous, and can cause major health issues. In this paper image processing techniques and deep learning methods are explained to find out the chemicals present.
Recycling of grounds for the construction of the railway subgrade
Authors: Golubev O. V. , Filatova A. M.
Published: June 2023

The relevance of the issue of construction waste management is considered on the example of soil during the construction of the railway track. The main requirements for the soils of the subgrade, as one of the components of the railway track, ensuring the safety of rolling stock movement, are listed. Definitions of construction waste and recycling are given; classification of waste generated during the dismantling and repair of railway track facilities in accordance with regulatory documents. The advantages, the main task of recycling, as well as the main reasons that exclude this method in solving the problem of getting rid of construction waste are indicated. The main pollutants of the soil, which is removed during the repair of the railway track, have been identified. The methods of utilization of soils for the construction of the railway subgrade containing petroleum and organic inclusions are considered. The main methods of extracting petroleum products, depending on the degree of contamination and terrain conditions, taking into account efficiency and environmental safety: physico-chemical method, cutting out the top layer of soil, washing with high-pressure water jets and pumping out pulp, microbiological cleaning, washing using drainage systems, capillary absorption of porous materials and others. Peat processing methods: production of pellets, pyrolysis, hydrolysis.
St. Petersburg College of Railway Transport is 105 years old: development forecast
Authors: Shekhtman E. I. , Shutov I. N. , Bykova O. V.
Published: June 2023

The historical aspects of the development of the system of personnel training for railways at the level of secondary vocational education are studied. The main stages of the formation, development and current state of the St. Petersburg College of Railway Transport are given. The results of the introduction of modern technologies for training transport technicians are shown.

The relevance of the study is related to solving the problems of secondary vocational education in the preparation of students in working specialties with their further promotion in the system of continuous education to personnel of higher professional qualifications. The issues of prospects for the development of targeted training for the training of employees for transport structures according to a personal educational program are touched upon. As directions for optimizing secondary vocational education, methods are proposed for developing cognitive interest in mastering professional competencies, introducing mentoring at enterprises and strengthening the professional orientation of the educational process. In the laboratories of the technical school, students collectively solve specific production problems, analyze situations, participate in business games, production quests at railway transport enterprises, etc. The participation of students in the championships of professional skills, demonstration exams in the logic of strengthening the professional orientation of training for the preparation of a highly qualified transport technician with a diploma of secondary vocational education is considered.
75 years of the Volgograd Technical School of Railway Transport — branch of the Rostov State Transport University
Authors: Volkova A. F.
Published: June 2023

The history and present days of the Volgograd Technical School of Railway Transport, a branch of the Rostov State Transport University, are considered. An innovative educational space has been formed in the technical school, within which teachers have developed personal websites with interactive elements, electronic learning modules, electronic laboratories, the idea of creating an educational mini-quantorium is being implemented.

From the moment of its formation to the present day, the technical school conducts specialized training of mid-level specialists for railway transport enterprises. Classrooms, laboratories, workshops are equipped with modern training complexes, software that allows students to solve professional problems.

The innovative educational space of the technical school not only provides training for a specialist in the railway industry who is competitive in the labor market, versed in related fields of activity, able to improve in professional skills, but also synchronizes training in accordance with the needs of the labor market. Today, the technical school is a modern educational institution that trains railway industry specialists who are in demand on the modern labor market under secondary vocational education programs.
Pentingnya Perilaku Pelaksana Regulasi untuk Pencapaian Indeks Inovasi Daerah yang Tinggi
Authors: Deru H. Herman , Sobri Kiagus Muhammad , Alfitri Alfitri , Leonardo Andreas , Prasetyo Eko
Published: June 2023

Inovasi daerah merupakan salah satu faktor yang dapat mendorong kemajuan suatu daerah. Pemerintah telah menetapkan beberapa kebijakan yang mengamanatkan inovasi daerah. Implementasi kebijakan inovasi daerah menjadi penentu kesuksesan atau kegagalan inovasi di daerah, sehingga dirasa penting untuk melakukan Studi Implementasi kebijakan Inovasi Daerah. Penelitian ini bertujuan untuk mengetahui kinerja implementasi kebijakan, dan menggali faktor yang mempengaruhi kinerja kebijakan inovasi daerah. Desain penelitian dipilih studi kualitatif yang dilakukan di Provinsi Sumatera Selatan. Teknis pengumpulan data dilakukan melalui wawancara mendalam pada 47 Informan kunci dan telaah dokumen. Analisis data dilakukan secara deskriptif, induktif, dan analisis konten. Hasil penelitian menunjukkan bahwa kinerja implemetasi kebijakan inovasi daerah Provinsi Sumatera Selatan tahun 2022 sangat baik dengan skor Indeks Inovasi daerah (79,47), provinsi terbaik secara Nasional. Kinerja Kebijakan tersebut dipengaruhi oleh perilaku pelaksana, sikap pelaksana, karakteristik organisasi, komunikasi antarorganisasi, kondisi sosial, ekonomi, dan politik, sumber daya, dan pemahaman terhadap standar dan sasaran kebijakan. Variabel perilaku pelaksana merupakan temuan khusus dalam penelitian ini yang memperkaya Teori Imlementasi Kebijakan Van Meter Van Horn. Disimpulkan bahwa diperlukan komitmen kepala daerah dan perilaku positif dari seluruh jajaran dalam mengimplementasikan kebijakan inovasi daerah untuk meningkatkan indeks inovasi daerah.
Minat Remaja Masjid terhadap Kegiatan Dakwah di Kampung Buatan II Kecamatan Kotogasib Kabupaten Siak
Authors: Hafiz Muhammad
Published: June 2023

Abstrak

Ikatan remaja masjid merupakan, perkumpulan remaja-remaji, untuk memkamurkan masjid, membina dan menanamkan nilai-nilai agama, agar tidak menyimpang kepada aturan-aturan yang berlaku, organisasi remaja masjid ini telah melaksanakan kegiatan-kegiatan yang sifatnya membangun akhlak dan budi pekerti, remaja iku andil dalam pelaksanaan kegiatan dakwah tersebut seperti, ta’ziah, wirid remaja, bergotong royong. Permasalahan yang di angkat dalam penelitian ini bagaimana minat remaja masjid terhadap kegiatan dakwah. Penelitian digunakan dalam penelitian ini adalah penelitian lapangan (Field Research), serta tehnik yang digunakan adalah purpusive sampling, penelitian ini berkenaan minat remaja masjid terhadap kegiatan dakwah. Hasil penelitian menunjukkan bahwa remaja masjid berperan aktif mengikuti setiap pelaksanaan kegiatan dakwah tersebut.
STRATEGI PEMASARAN PEDAGANG IKAN KERING MELALUI MEDIA SOSIAL DIMASA PANDEMI COVID 19
Authors: Yeni Yasyah Sinaga
Published: June 2023

Abstrak

Penelitian ini bertujuan untuk mengetahui bagaimana strategi pemasaran Ikan kering seperti ikan asin dan ikan teri melalui media sosial dimasa pandemi covid 19 di Desa Tualang. Disini peneliti menggunakan jenis penelitian kualitatif dengan terjun langsung kelapangan melakukan observasi dan wawancara kepada para pedagang di Desa Tualang. Kemudian ditemukan hasil tetang strategi pemasaran pedagang Ikan kering seperti ikan asin dan ikan teri melalui media sosial di masa pandemi covid 19 ini bahwa para pedagang melakukan promosi dengan menggunakan media sosial yaitu melalui Facebook dan Whatsaap dengan dukungan masyarakat sehingga meningkatkan minat para konsumen sehingga mereka tertarik serta berkeinginan untuk memberi Ikan kering seperti ikan asin dan ikan teri. Dalam penelitian ini juga ditemukan kendala pada para pedagang ikan kering yaitu ada beberapa pedagang yang masih belum bisa menggunakan smartphone sehingga mereka mengalami kesulitan untuk menggunakan media sosial secara online hal itu disebabkan karena kondisi umur merka yang sudah cukup tua.

Kata Kunci: Strategi Pemasaran, Media sosial, Ikan Kering

Abstract

This study aims to find out the marketing strategy for dried fish such as salted fish and anchovies through social media during the Covid 19 pandemic in Tualang Village. Here the researcher uses a type of qualitative research by going directly to the field to conduct observations and interviews with traders in Tualang Village. Then it was found the results regarding the marketing strategy of dried fish traders such as salted fish and anchovies through social media during the Covid 19 pandemic that traders carried out promotions using social media, namely through Facebook and Whatsaap with community support so as to increase consumer interest so that they are interested and willing to give dry fish such as salted fish and anchovies. This study also found obstacles to dried fish traders, namely that there were some traders who still could not use smartphones, so they had difficulty using social media online. This was due to their old age.

Keywords: Marketing Strategy, Social Media, Dried Fish
Penggunaan Media Gambar dalam Meningkatkan Hasil Belajar Ipa Siswa Kelas Vii Upt Smp Negeri 3 Anggeraja Kabupaten Enrekang
Authors: Jumiati Jumiati
Published: June 2023

The formulation of this research problem is whether the use of image media can improve the learning outcomes of grade VII students in science subjects UPT SMP Negeri 3 Anggeraja, Enrekang Regency. This goal is to find out whether the use of image media can improve the learning achievement of science class VII circulatory device material in humans. This type of research is Classroom action reasearch. The subject of this study was class VII UPT SMP Negeri 3 Anggeraja Enrekang Regency which amounted to 26 students. Data collection techniques in this study are by observation, written tests. From the results of the study, it can be concluded that using Image media can improve the learning outcomes of grade VII students in the science subjects of UPT SMP Negeri 3 Anggeraja. This can be seen from the improvement in each cycle. Where in the initial ability (pretest) obtained learning results with an average of 55 and a percentage of completeness of 42%, for that the researchers carried out cycle I, the results obtained with an average value of 64 and a percentage of completeness of 57%, then carried out cycle II increased with an average value of 75 and learning completeness of 88%.
Peningkatan Hasil Belajar Materi Keragaman Sosial dan Budaya Indonesia Menggunakan Pembelajaran Kooperatif Tipe SAL
Authors: Mukhtar Mukhtar
Published: June 2023

The purpose of this study is to Improve Learning Outcomes of Indonesian Social and Cultural Diversity Material Using SAL Type Cooperative Learning for Class VII Students of UPT SMP Negeri 4 Enrekang. The method used in this study is Action Research which consists of 2 (two) cycles, and each cycle consists of: Planning, Implementation, Observation, and Reflection. Based on the results of action research that SAL Type Cooperative Learning can Improve Learning Outcomes of Indonesian Social and Cultural Diversity Material for Class VII Students of UPT SMP Negeri 4 Enrekang. Furthermore, the researchers recommend: (1) For teachers who have the same difficulties can apply SAL Type Cooperative Learning to improve Learning Outcomes. (2) In order to get maximum results, teachers are expected to make SAL Type Cooperative Learning more interesting and varied
Determinant Analysis Of Marine Fishermen's Income In Denpasar City
Authors: Evelinda Renita , Suasih Ni Nyoman Reni
Published: June 2023

According to data from BPS Bali Province, Denpasar City's fishing production value is high, coming in at Rp943,607,030. Fishermen's income, however, is lower than that of farmers and artisans because it is based on the capital and operating expenses for each voyage. If supported by a relatively appropriate physical and financial infrastructure, processing of fish products will increase. In this study, the effects of capital, fishing experience, ship ownership status, working hours, and fish capture on marine fishermen's income were examined. Using the SPSS program, perform a multiple linear regression analysis on the data. With a sample size of 91 respondents, secondary and primary data were employed. The findings demonstrated that a number of factors, including money, fishing experience, ship ownership status, working hours, and fishing itself, have an impact on the revenue of marine fishermen in Denpasar City. While boat ownership status and working hours partially do not have a major impact on the income of marine fisherman in Denpasar City, capital, fishing experience, and fish catches do have a big impact.
Implementasi Pelayanan Konseling Apoteker Model Servqual Terhadap Pasien Klinik Muizzah Di Kecamatan Rengat Barat, Riau
Authors: Lestari Oktri , Wahyuni Lila , Fitriani Riri Amanda , Panca Priyanda Elza Rachman , Utami Ayu Dwi
Published: June 2023

Pharmacist counseling is a component that must be provided by pharmacists when dispensing drugs to patients. This includes one form of service in health institutions, namely pharmaceutical services. Pharmaceutical service is a direct and responsible service to patients related to pharmaceutical preparations with a view to improving the quality of life of patients. Assessment of the quality of pharmaceutical services can be done based on patient satisfaction. In this study, patient satisfaction with pharmacist counseling services can be done using the SERVQUAL model which has 5 dimensions, namely tangible dimensions (real evidence), reliability (reliability), responsiveness (responsiveness), assurance (guarantee), and empathy (empathy). This study aims to review the most prominent results on these 5 dimensions and with a total of 40 respondents in the form of several questions (questionnaires). Based on the implementation of pharmacist counseling in services to patients at the Muizzah clinic using the SERVQUAL model, it was found that of the 5 dimensions the highest was the assurance value of 90.1%. Many patients expect the competence of pharmacists to instill trust and confidence in patients, such as the performance of pharmacists who are competent, professional and are expected to provide input to the clinic to improve the quality of service for each patient.
Peranan Pre dan Post Ischemic Conditioning Sebagai Pencegahan Cedera Reperfusi
Authors: Zein Hamzah Muhammad
Published: June 2023

Reperfusi pneada jaringan iskemik sering mengakibatkan proses patofisiologi, seperti gangguan endotelium pada arteriol, peradangan dan ekstravasasi protein plasma di venula. Ada berbagai mekanisme yang menyebabkan cedera reperfusi. Salah satu mekanismenya adalah dengan diproduksinya radikal oksigen sehingga dapat melepaskan mediator inflamasi. Manifestasi klinis yang timbul juga beragam, salah satu contohnya, pada jantung, dapat terjadi myocardial stunning. Penulisan literature review ini bertujuan untuk memahami peranan pre dan post ischemic conditioning sebagai pencegahan cedera reperfusi sehingga dapat mengarahkan ke asesmen dan pemberian terapi yang tepat kepada pasien. Secara epidemiologi, cukup banyak didapatkan kejadian cedera reperfusi yang tidak mendapatkan manajemen yang memadai, sehingga diperlukan pembahasan peranan pre dan post ischemic conditioning dari berbagai literatur. Literature review ini dilakukan pada April 2019 dengan mengambil sumber data dari berbagai sumber buku dan jurnal medis. Referensi yang diambil dari original research dan buku. Ada berbagai studi yang mengungkapkan  terapi atau tindakan untuk mencegah cedera reperfusi, yaitu ischemic conditioning. Fokus terapi atau tindakan untuk mencegah cedera reperfusi berdasarkan mekanisme-mekanisme yang terjadi pada cedera reperfusi. Mekanisme ischemic conditioning mencegah cedera reperfusi dengan cara mencegah apoptosis, onkosis, dan meningkatkan antioksidan. Mekanisme ischemic conditioning ini berawal dari stimulus dan aktivasi terhadap sinyal transduksi kardioproteksi. Sinyal ini memiliki efek akhir untuk menghambat pembukaan mPTP, sehingga efek cedera reperfusi bisa dikurangi.
Treynor, Sharpe, and Jensen Ratio of Health Sector Companies on The Indonesia Stock Exchange Before and During Covid-19 Pandemic Period
Authors: Tamara Dewi , Ashuri Ashuri , Bagaskara Satria Katon , Sulhadi Sulhadi
Published: June 2023

This research aims to compare the return and risk in investment at the stock portfolio of Health Sector Companies in period before the COVID-19 pandemic and during the COVID-19 pandemic in Indonesia. This research conducted using quantitative method with descriptive approach with secondary data with samples of the stock of Health Sector Companies listed in the Indonesia Stock Exchange ("IDX") which then formulated into a stock portfolio. The research period used is the period March 2019-Feb 2020 for before COVID19 pandemic, and the period March 2020 - Feb 2021 for during the COVID19 pandemic. The stock portfolio return and risk measurement is measured by Sharpe, Treynor, and Jensen Ratio which then will be statistically tested to see if there are significant differences of ratios between the two conditions.
Socialization of the Importance of the Agency's SPT Strategy and Development UMKM Strategy in Parungpanjang District
Authors: Mu `Arifin Hidayatul , Sari Dewi Siti Ratna , Rosini Iin
Published: June 2023

The purpose of this research is to provide an understanding of the making of the Agency's Annual SPT and the development strategy of MSME-IKM and to find out what obstacles are faced during the MSME-IKM Kec Forum. Parungpanjang at the time of making the annual corporate tax return. To achieve this goal, training activities for the preparation of the Agency's Annual SPT were carried out in UMKM-IKM Kec. Parungpanjang. The method used in this research is through training and coaching activities. The data collection method used in this study is a quantitative and descriptive method, namely by reviewing, researching, and providing training and guidance to companies in recording transactions and making annual and periodic tax returns. Thus making the company more effective and efficient in dealing with financial reporting and tax reporting issues. This bookkeeping and recording becomes a very crucial thing because what is recorded or recorded will be the basis for every taxpayer to calculate the amount of tax owed. From the results of this study, financial transactions have not been properly recorded into financial statements, although simple because there are many obstacles in making the annual corporate tax return, one of the factors is that human resources or managers do not understand a
Kualitas Soal Ujian Akhir Sekolah Mata Fisika SMA Negeri Se- Kota Baubau
Authors: Usman Minarti
Published: June 2023

Dalam rangka pencapaian tujuan pendidikan nasional maka pemerintah berupaya meningkatkan mutu pendidikan mulai dari jenjang sekolah dasar sampai perguruan tinggi. Penelitian ini bertujuan untuk mengetahui kualitas soal Ujian Akhir Sekolah mata pelajaran fisika kelas XII IPA SMA Negeri di Kota Baubau Tahun Pelajaran 2017/2018 dengan melihat validitas, reliabilitas, tingkat kesukaran, daya beda dan efektivitas pengecohnya. Jenis penelitian yang digunakan adalah penelitian deskriptif kuantitatif dengan subjek penelitian lembar jawaban hasil ujian akhir sekolah mata pelajaran fisika kelas XII IPA SMA Negeri se-Kota Baubau yang terdiri dari 400 peserta didik. Hasil penelitian menunjukkan validitas isi soal ujian akhir sekolah mata pelajaran fisika kelas XII IPA SMA Negeri se-Kota Baubau telah valid secara isi dengan koefisien validitas sebesar 0,943, validitas kriteria soal ujian akhir sekolah mata pelajaran fisika kelas XII IPA SMA Negeri se-Kota Baubau terdapat 9 butir soal tidak valid dari 35 butir soal yang diujikan, tingkat kesukaran soal ujian akhir sekolah mata pelajaran fisika kelas XII IPA SMA Negeri se-Kota Baubau memiliki sebaran tingkat kesukaran yang tidak proporsional dengan perbandingan sukar, sedang, dan mudah adalah 12, 2, dan 21, daya beda soal ujian akhir sekolah mata pelajaran fisika kelas XII IPA SMA Negeri se-Kota Baubau terdapat 14 butir soal yang memiliki daya beda sangat baik, 6 butir soal dengan daya beda baik, 1 butir soal dengan daya beda kurang baik dan 14 butir soal yang memiliki daya beda tidak berfungsi, efektivitas pengecoh, soal ujian akhir sekolah mata pelajaran fisika kelas XII IPA SMA Negeri se-Kota Baubau secara keseluruhan tidak dapat dapat dikatakan efektif atau berfungsi karena dari 35 butir soal yang di ujikan hanya terdapat 2 butir soal yang efektivitas pengecohnya berfungsi, dan reliabilitas, instrumen soal ujian akhir sekolah mata pelajaran fisika kelas XII IPA SMA Negeri se-Kota Baubau reliabel atau konsisten dengan koefosien reliabilitas instrument sebesar 0,741.
Pengaruh Budaya Organisasi, Kepemimpinan, dan Kompetensi Terhadap Kinerja Pegawai
Authors: Ulyanah Siti , Syafrudin Endin , Hussen Saddam
Published: June 2023

Organisasi merupakan salah satu hal yang bisa menjadikan manusia menjadi manusia yang membentuk karakter pemimpin. Tujuan penelitian ini adalah untuk mengetahui dan menganalisis apakah budaya organisasi, kepemimpinan, dan kompetensi mempengaruhi kinerja pegawai di lingkungan LKPP secara parsial maupun secara simultan. Penelitian ini merupakan studi kasus yang mempelajari secara khusus dan mendalam mengenai budaya organisasi, kepemimpinan, kompetensi dan kinerja pegawai. Variabel independen penelitian adalah budaya organisasi, kepemimpinan dan kompetensi. Variabel dependen penelitian adalah kinerja pegawai. Pendekatan penelitian yang digunakan adalah pendekatan kuantitatif dengan dengan menggunakan kuisioner. Populasi penelitian ini adalah 297 pegawai di lingkungan LKPP dan menggunakan analisis regresi berganda dengan tujuan mengetahui pengaruh variabel independen budaya organisasi, kepemimpinan dan kompetensi terhadap variabel dependen yaitu kinerja pegawai. Hasil penelitian menunjukkan bahwa secara simultan budaya organisasi, kepemimpinan dan kompetensi berpengaruh signifikan terhadap kinerja pegawai. Budaya organisasi secara parsial berpengaruh signifikan terhadap kinerja pegawai, kepemimpinan tidak berpengaruh signifikan terhadap kinerja pegawai dan kompetensi berpengaruh signifikan terhadap kinerja pegawai
Penggunaan Aplikasi Whatsapp Groupping Terhadap Hasil Belajar Menulis Geguritan Di Masa Pandemi Covid-19 Pada Siswa Kelas 9H SMPN 1 Karanggayam, Kebumen
Authors: Budiono Agus
Published: June 2023

Covid-19 is a big challenge for Indonesians, it affects various aspects, in addition to economic aspects many aspects are also harmed by Covid 19 aspk other aspects, namely aspectsofEducation. This research aims to find out the results of learning to write in the pandemic period in students of grade 9H SMPN 1 Karanggayam, Kebumen in the 2nd semester of the 2020/2021 school year and to find out the learning results of students in using the WhatsApp Grouping application. The method used in this study is a descriptive quantitative research method, with a sample of students of SMPN 1 Karanggayam. This research data collection technique uses observation techniques, questionnaires and recording techniques. The data collection instrument used in the study was an online learning questionnaire. The results of research in the use of WhatsApp media showed that the results of learning to write a rebuke against the results of grades that are not 100% most students have grades that are less or below KKM