bluuebunny/crossref_metadata_2025 huggingface dataset:
Bioactive molecules from Algerian propolis with therapeutic potential against the oral pathogen Enterococcus faecalis and Chromobacterium violaceum CV026
Authors: Mokrani Meryem , Zellagui Amar , Hadjab Widad , Öztürk Mehmet , Ceylen Ozgur , Bensouici Chawki
Published: July 2023

This research aims to analyse the richness of propolis ethanolic extract from Kherrata (EEPKh) in phenolic and flavonoid compounds and its antioxidant effects using different methods. Further investigations were conducted to evaluate the antibacterial and antibiofilm potential of propolis against Enterococcus faecalis strains originated from oral diseases. The antiquorum-sensing ability against Chromobacterium violaceum CV 026 was also investigated. The results revealed that ethanolic extract contains a high content of phenolic and flavonoid compounds, with an amount of 734.3 9± 11.54µg GAE.mg-1 of Extract and 224.30 ± 0µg QE.mg-1of extract respectively. Caffeic acid (23.79 mg.g-1), hesperetin (15.42 mg.g-1), cynarin (7.59 mg.g-1), apigenin (5.91 mg.g-1), naringenin (4.90 mg.g-1), and kaempferol (3.43 mg.g-1) were identified as the major compounds by the HPLC-DAD analysis. The antioxidant activity showed good scavenging and reducing abilities. Furthermore, EEPKh demonstrated high antibacterial potency against E. faecalis strain 2 at concentration 20 mg.mL-1 with an inhibition diameter of 20.33 ± 0.57 mm. The MIC and MBC values were found to range between 0.625 and 10 mg.mL-1. Biofilm formation by E. faecalis strains was inhibited at MIC with a percentage ranging from 65.93 ± 1.11 to 51.54 ± 0.81%. Quorum sensing mechanisms in CV 026 was inhibited by EEPKh, with diameter zone of 11.16 ± 0.29 mm at MIC. This study indicated that propolis extract is considered as a new source of natural medication with therapeutic potential against oral pathology caused by free radicals, E. faecalis, biofilm formation and quorum-sensing.
IMPLEMENTASI PELAYANAN PRIMA (SERVICE EXCELLENCE) PADA UNIT FRONT OFFICE DI BSI KC CIANJUR SILIWANGI
Authors: Hidayat Indra Muhammad Syarief , Nur’aini Alifah Lufita , Resti Neng Hesyah
Published: July 2023

ABSTRAKPerbankan adalah badan usaha yang bergerak dibidang jasa, dimana standar layanan merupakan salah satu faktor penting yang harus dimiliki oleh bank dalam aktivitasnya. Kepuasan nasabah dapat dicapai dengan adanya pelayanan prima dari seluruh unit kerja yang terdapat pada bank, termasuk salah satunya unit kerja layanan pelanggan. Tujuan dari penelitian ini adalah untuk mengetahui apakah bank Bank Syariah Indonesia (BSI) kantor cabang Cianjur Siliwangi sudah menerapkan pelayanan prima kepada para nasabahnya guna menjaga loyalitas nasabah tersebut. Metode penelitian yang digunakan pada penelitian ini adalah metode kualitatif, yaitu penelitian yang bermaksud untuk memahami fenomena tentang apa yang dialami oleh subjek penelitian secara holistik dan dengan cara deskripsi dalam bentuk kata-kata dan bahasa. Adapun Teknik yang digunakannya adalah dengan melakukan pengamatan (observasi) langsung serta wawancara kepada sampel karyawan layanan pelanggan dan nasabah. Hasil dari penelitian menunjukkan bahwa bank BSI kantor cabang Cianjur Siliwangi secara garis besar sudah mendekati kepada penerapan pelayanan prima, namun masih terdapat hal-hal yang perlu ditingkatkan guna meminimalisir komplain serta menjaga loyalitas nasabah.ABSTRACTBanking is a business entity engaged in the service sector, where service standards are one of the important factors that a bank must have in its activities. Customer satisfaction can be achieved through excellent service from all units within the bank, including the customer service unit. The objective of this study is to determine whether Bank Syariah Indonesia (BSI), Cianjur Siliwangi branch, has implemented excellent service for its customers in order to maintain their loyalty. The research method used in this study is qualitative research, which aims to understand the phenomena experienced by the research subjects holistically through descriptive words and language. The technique used includes direct observation and interviews with customer service staff and customers as samples. The results of the study indicate that, in general, Bank BSI, Cianjur Siliwangi branch, has approached the implementation of excellent service, but there are still areas that need improvement in order to minimize complaints and maintain customer loyalty.
Rekomendasi Kebijakan Dukungan DPUTR Dalam Pengelolaan Sampah di DAS Citarum
Authors: Fauzana Fauzana
Published: July 2023

Citarum River is the longest river in Province of West Java. Citarum River Basin covers 13 regencies/cities and 1.454 villages (Data RBI, 2018), consisting of 16 sub-basin spread across the upstream, middle, and downstream parts. Middle part of this basin crosses the north to middle part of Cianjur Regency. One of the problems in this basin is the presence of garbage which degrades river quality. In Cianjur Regency, solid waste management is the task of the Dinas LH (Environmental Service), but synergistic efforts between related departments is needed, including the PUTR (Public Works and Spatial Planning Office), so that solid waste problems can be handled optimally. By using the Readiness Criteria for Solid Waste Infrastructure, PUTR Office becomes a stakeholder for 2 criterias: conformity with spatial planning and adequate road access. This role can be carried out by actively coordinating spatial planning with the Dinas LH so that the location of solid waste infrastructure is in accordance with spatial planning and improving access (road infrastructure) to the Solid Waste Infrastructure to support waste transportation. In addition, there needs to be cooperation between the PUTR Office and the LH Service regarding the handling of solid waste that has entered water bodies. These roles need to be put into consideration in preparing budget plans in the Spatial Planning Implementation Program, the Water Resources Management Program, and the Road Implementation Program.
Determinants of the formation of the radical consciousness of youth
Authors: Nikitina Lyudmila , Konopleva Anna , Chudina-Shmidt Natalya
Published: July 2023

Introduction. Young people, as the most potentially passionate part of the society, are characterised by maximalism and a strong desire to conquer the world here and now. However, their immature worldview can easily lead this category of the population to lose their true identity by being influenced by radicals. The radicalisation of mass consciousness in the current global context has become a feature of the modern society, resulting in an obstacle to the positive development of Russia. This fact raises the need for research on the determinants of the formation of radical consciousness in order to further effective preventive activities in this direction.

The purpose of the research is to identify the main causes and conditions for the formation of radical consciousness among young people.

Methodology, methods and techniques. The conducted research is based on modern scientific, methodological and sociopsychological characteristics of the formation of radical consciousness. The dialectical method, the method of ascending from the abstract to the concrete, comparative studies, and axiological interpretation are used.

The results of the research testify to the relevance of the issue of study, especially in the current conditions of society development. The main, and at the same time, diverse (social, psychological, cultural, political) aspects contributing to the formation of radical views of young people are analysed.

The scientific novelty of the article is substantiated by the analysis of the existing world environment (maximally favourable for the formation of radical consciousness) and the scientific researches performed within the framework of the subject, which made it possible to conclude that the problem under consideration is underdeveloped.

Practical significance. The results of the research can fill the existing gap in the study of the mentioned subject and become a support for further comprehensive problem examination, as well as contribute to preparing scientific support for preventive activities in relation to the negative side of radicalism of young people.
A Student Engagement in a Virtual Class by FLIP Learning Application
Authors: Iswandari Amelia
Published: July 2023

Engagement is very crucial in the virtual language learning process and needs to be always maintained. One way to keep learning engagement is the application of the FLIP Learning approach with its four pillars, including Flexible surroundings, Learning Culture. Intentional Content, Professional Educators. This study aimed to find out the occurrence of engagement in virtual Speaking classrooms, as well as pinpoint the most influential pillar of FLIP Learning in the class. The research used a qualitative method by conducting surveys and class observations for data collection. The respondents were 50 students from virtual Speaking classes in semester 1 of the academic year 2021/2022 of STBA LIA Jakarta. It was revealed that learning engagement occurred, and Professional Educators is the most influential factor out of four pillars of FLIP Learning in the virtual Speaking Classes.
Implementation of Hybrid Encryption Algorithm
Authors: - Riwaz Udas , - Pranav Kumar jha , - Monu Agrawal
Published: July 2023

The vulnerabilities of using a single encryption system in messaging systems has proven to become increasingly problematic in recent days, this paper provides a new form of encryption to be used in such systems. The proposed system is a new combination of two very prevalent encryption algorithms namely the Vigenere encryption algorithm and the Base-64 encryption (also known as B64 encryption). The combined encryption algorithm is made by using the Base-64 encryption followed by the Vigenere algorithm. Each message sent by the user is secured after being greatly enhanced through this encryption technique.
DETERMINANTS OF STUNTING PROBABILITY AMONG CHILDREN IN BELU DISTRICT AND NORTH CENTRAL TIMOR, EAST NUSA TENGGARA PROVINCE
Authors: Seran Sirilius , Yanti Akoit Maria , F.W.A. Fouk Maria
Published: July 2023

Children with stunting are noticeably shorter in height and are skinnier than their peers. This condition arises from the malnourishment they encounter during their time in the womb and the two years following their birth. The parents’ socio-economic conditions can be one of the contributing factors that enhances the likelihood of a child experiencing stunting. This paper utilizes a sample of 300 households from North Central Timor and Belu regions as respondents. In this paper, the probability of stunting is labeled as variable category 1 and 0. As a result, the appropriate inferential analysis tool to be employed is logistic regression. On the other hand, the independent variables are as follows: 1) income, 2) wife’s employment status, 3) wife’s education, 4) husband’s education, 5) birth spacing. The analysis result proves that only the birth spacing variable has a negative relationship (-0.332) but is not statistically significant (Sign.) in relation to the probability of stunting in children under five years olds. The likelihood of children experiencing stunting is higher when the parents have a low income, 3 to 4 times higher than parents with higher income. On the other hand, the risk of stunting for children with fathers having low educational level is 3,759 times higher compared to those with higher education.
Transcutaneous electrical acupoint stimulation in adult patients receiving gastrectomy/colorectal resection: A randomized controlled trial
Authors: Hou Yuan-Tao , Pan Yuan-Yuan , Wan Lei , Zhao Wen-Sheng , Luo Ying , Yan Qi , Zhang Yi , Zhang Wei-Xin , Mo Yun-Chang , Huang Lu-Ping , Dai Qin-Xue , Jia Dan-Yun , Yang Ai-Ming , An Hai-Yan , Wu An-Shi , Tian Ming , Fang Jian-Qiao , Wang Jun-Lu , Feng Yi
Published: July 2023

Obstructive jaundice (OJ) is a common problem in daily clinical practice. However, completely understanding the pathophysiological changes in OJ remains a challenge for planning current and future management. The effects of OJ are widespread, affecting the biliary tree, hepatic cells, liver function, and causing systemic complications. The lack of bile in the intestine, destruction of the intestinal mucosal barrier, and increased absorption of endotoxins can lead to endotoxemia, production of proinflammatory cytokines, and induce systemic inflammatory response syndrome, ultimately leading to multiple organ dysfunction syndrome. Proper management of OJ includes adequate water supply and electrolyte replacement, nutritional support, preventive antibiotics, pain relief, and itching relief. The surgical treatment of OJ depends on the cause, location, and severity of the obstruction. Biliary drainage, surgery, and endoscopic intervention are potential treatment options depending on the patient's condition. In addition to modern medical treatments, Traditional Chinese medicine may offer therapeutic benefits for OJ. A comprehensive search was conducted on PubMed for relevant articles published up to August 1970. This review discusses in detail the pathophysiological changes associated with OJ and presents effective strategies for managing the condition.
Exploring the Transformative Impact of Language Teachers' Autoethnographies in a Teacher Education Course
Authors: Arshavskaya Ekaterina , Reyes de la Paz Nefi
Published: July 2023

Benefits of teachers' autoethnographies are well-documented in current research. This study adds to the research literature by directly analyzing how the insights gained through writing autoethnographic essays may impact second language (L2) teachers' classrooms. To collect the data, the study incorporated autoethnographic essays into a graduate course for language teachers and asked the participating teachers to design lessons that reflected the insights they gained about themselves through this project. Adopting the transformative learning theory (Mezirow, 1978, 1997) that scaffolds teachers' self-reflection, this paper explores the transformative potential of teachers' autoethnographies through tracking qualitative changes in the teachers' narratives and practice across one academic semester. The results show that as a learning tool, autoethnographies can facilitate teachers' developing more empowering teaching identities and have a potential for enhancing their teaching practices. The paper adds empirical evidence and a new perspective in the investigation of teacher learning. It concludes with pedagogical and research implications for L2 teacher education.
Codonopsis thalictrifolia Wall. var. mollis (Chipp.) L. T. Shen exhibits anti-inflammatory activity against LPS-induced RAW264.7 cells and peritonitis in mice
Authors: Zheng Rui , Yuan Ruiying , Dongzhi Zhuoma , Li Xinyu , Xie Mi , Wang Jule , Li Bin , Huang Shan
Published: July 2023

Codonopsis thalictrifolia Wall. var. mollis (Chipp.) L. T. Shen (C. thalictrifolia), a traditional medicinal plant used in Tibetan medicine, has been previously reported to exhibit a variety of pharmacological characteristics. In the present work, we assessed the anti-inflammatory action of 70% ethanolic extract of C. thalictrifolia (ECW) on RAW264.7 cells induced by lipopolysaccharide (LPS) and mice with peritonitis. High-performance liquid chromatography analysis of ECW identified two major compounds, caffeic acid and luteolin. Our results demonstrate that ECW remarkably repressed the generation of pro-inflammatory mediators, which include interleukin-6 (IL-6), cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), nitric oxide (NO), tumor necrosis factor α (TNF-α), and interleukin-1β (IL-1β), in the RAW264.7 cells stimulated with LPS. Moreover, ECW suppressed LPS-induced degradation and phosphorylation of IκBα and the nuclear translocation of nuclear factor kappa B (NF-κB) p65 in RAW264.7 cells, indicating its modulation of pathway of NF-κB. In peritonitis mice induced by LPS, ECW treatment ameliorated disorders of immune cells and decreased the pro-inflammatory mediator levels. Our findings suggest that C. thalictrifolia possesses potent anti-inflammatory activity, probably via modulating the NF-κB signaling pathway.
Research On Evolution Of Quality Chain Network Model Based On Multi-Attribute Weighting Of Complex Network
Authors: Luo Juanjuan , Yin Haohao
Published: July 2023

Using the linear optimal connection mechanism of complex network model, a multi-attribute weighted quality chain network model construction method is proposed. Firstly, the enterprise node in the quality chain is defined to have its own attributes of quality elements and node business relevance. Secondly, the degree and the intermediate number are combined to comprehensively consider the local and global characteristics of the network to express the network attributes of the node, and the multi-attribute weighted quality chain network edge connection strategy algorithm is designed under the combination with the node’s own attribute weighting. Finally, the simulation results show that the quality chain network model established by this strategy meets the scale-free characteristics and has higher network efficiency and stronger network invulnerability which proves that the newly established model is reasonable.
1 - New Executive Committee Members
Authors: Journal system
Published: July 2023

Abstract
3 - Sam Moyo: Speeches from the Archives - We are proud that CODERIA has Sustained itself over the Decades
Authors: Journal system
Published: July 2023

Abstract
13 - (Re) making Bodies: The Structures and Dynamics of Aesthetics and Aspirations in an Evolving Africa: Report on the international conference held in Dar es Salam, Tanzania, 3-4, November, 2016
Authors: Onoma Ato Kwamena
Published: July 2023

Abstract
11 - Faith-based Segregation of Interments in Joal-Fadiouth: Report of a Dissemination Seminar
Authors: Onoma Ato Kwamena
Published: July 2023

Abstract
20 - Tribute: Sam Moyo: One Year After
Authors: Amanor-Wilks Dede
Published: July 2023

Abstract
Transporte público y medios alternativos (TPA): dimensión social y necesidades en materia de comunicación
Authors: Cámara Molina José Carlos
Published: July 2023

El transporte colectivo ha pasado de ser percibido como solución de transporte para los menos pudientes a un símbolo de modernidad y desarrollo. En España, como en otros países industrializados, se ha realizado un enorme esfuerzo por extender y actualizar las líneas de tren, metro, tranvía y autobús, que prestan servicios de calidad, competitivos en precio y con externalidades positivas como la menor ocupación de espacio, entornos más limpios y silenciosos, y mejor imagen para las ciudades. Se propone investigar los elementos que determinan el éxito de este modelo desde el punto de vista social, que parece encajar con el pensamiento comunitarista de Amitai Etzioni, y la búsqueda de un «mínimo rico básico para todos», que elimine la exclusión social. Asimismo, se repasa la importancia de la comunicación para promocionar la imagen y el uso del transporte público y se proponen algunas áreas de interés
Curbing the Menace of Re-Cycling Smokers in a Population through Mathematical Modeling Approach
Authors: Isa Rwat Solomon , Abubakar Shehu Sidi , Garba Usman
Published: July 2023

Smoking can cause or trigger many diseases that can lead to death or disability. It affects the person’s financial status and therefore his way of life. Hence, its negative impact on smokers includes cancer, stroke, heart diseases, immune disorder, infertility, a complication of pregnancy, pollution, mental health, depression, aging, and anxiety. It also affected one’s financial status. We formulate a SEMRE deterministic model to assess the effect of re-cycling smokers into the population. We compute the basic reproduction number of the model, its equilibrium points and their stability, the sensitivity indices of the parameters of the basic reproduction number and we perform numerical analysis of the model to see how it tallies with the result of analytical calculation. Our model exhibits a backward bifurcation for some parameters’ values. By varying the recycling parameter, the model bifurcation changes from the backward bifurcation to forward bifurcation as the recycling parameter reduces.
Application of Remote Sensing for Environmental Management in Vietnam
Authors: Tu Thanh Tri
Published: July 2023

Remote sensing technology has become an important tool for environmental management in Vietnam. The country has a diverse range of environments, from dense forests to vast agricultural lands and coastlines, making remote sensing an ideal method for monitoring and managing natural resources. In this study, some examples of remote sensing applications for environmental management in Vietnam were studied in detail.
Marketing Mix Strategy of the Sasak Ende Tourism Village in Central Lombok Regency
Authors: Edwin Akhmad Fendro , Sudana I Putu , Sudiarta I Nyoman
Published: July 2023

This study aims to formulate the strategies of marketing mix and marketing programs for the Sasak Ende Tourism Village in Central Lombok district. The sampling technique used the Slovin model of Purposive Sampling technique which was distributed to 100 respondents/visitors. The data collection techniques used are in the forms of observation, questionnaires, interviews, literature studies, and documentations. While data analysis techniques are in the form of IFAS and EFAS analysis as well as the SWOT analysis. Based on the results of the IFAS strategy analysis, it is shown that the main strengths of the Sasak Ende Traditional Tourism Village in Central Lombok are attractions and building architecture presented by the Sasak Ende Traditional Tourism Village with a large rating (4.28), while the main weakness is the price of woven/songket clothes and souvenirs with a large rating (1.60). Furthermore, the results of the EFAS analysis shows that the main opportunity factor is following the development of information technology with a large rating (4.20), while the indicator which is the main threat is security stability in Lombok with a large rating (2.40). Based on the results of the SWOT analysis, the marketing mix strategy that are able to be applied to Sasak Ende Tourism Village is a strategy to improve the quality of tourism products, a strategy to develop the quality of sustainable human resources for tour guides, a strategy for developing facilities and infrastructure, a strategy for promoting tourism products through social media, a strategy for increasing promotion and re-branding of the Sasak Ende Traditional Tourism Village, strategies for standardizing the prices of tourism and creative economy products that are owned by competitors and strategies for innovation of tourism and creative economy products that are owned. Furthermore, there are several Marketing Mix programs that can be implemented in accordance with the formulation obtained from each strategy.
Inter-humanidad y buen vivir. El sujeto latinoamericano en la época de lo pos-humano
Authors: Viera Paparamborda José Eduardo
Published: July 2023

Reflexionamos sobre nuestros tiempos actuales, con avances tecnológicos y biológicos, habitados por pandemias y emergencias. Ubicamos dicha reflexión en características y contextos de nuestras culturas latinoamericanas, historizadas desde la colonialidad del saber y el poder. Nociones y conceptos como globalización, modernidad, posmodernidad, humanismo, posthumanismo, se problematizan desde esa construcción de América Latina y sus concretos modos de existencia actual y pasada. Intentamos ubicar al sujeto latinoamericano, desde una mirada distinta a la hegemónica y, desde allí, colocar otras formas de entender la vida, sostenidas desde saberes y prácticas ancestrales en nuestro continente (Abya Yala) que colocan el foco en la pluralidad, la nosotridad y la interhumanidad. En ese orden de lectura, proponemos algunas ideas planteadas desde la concepción del Buen Vivir (Suma Kawsay) y el Buen Convivir (Suma Qamaña) procedentes de las culturas andinas, que definen otra forma de entender al sujeto y su habitar en el mundo.
obras do espelho
Authors: Graña Roberto B.
Published: July 2023

O autor concede especial atenção aos conceitos de mutualidade, comunicação silenciosa e identificações cruzadas com o propósito de articular os três fenômenos, realçando a sua interdependência, enquanto constitutivos das relações de confiança e alteridade nos primeiros meses de vida. Embora a noção de mutualidade não seja parte das contribuições winnicottianas, mas as anteceda, o fato de havê-la descrito desde diferentes perspectivas e em conjunção com dois conceitos criados por ele, permitiu a Winnicott descrever as sutilezas semióticas da relação mãe-bebê e a forma silenciosa através da qual as permutas interativas irão possibilitar a tessitura da subjetividade primaria do infans num tempo em que o discurso e as palavras ainda não constituem o instrumento principal.
Transferência e modelo estético
Authors: Ungar Virginia
Published: July 2023

Cada modelo da mente se desprende de determinados elementos, que se conjugam de maneira constante e que estão relacionados à concepção da mente e à teoria do desenvolvimento emocional precoce de cada autor. Neste trabalho, seguimos a trajetória de Donald Meltzer, que percorre as idéias de S. Freud, M. Klein e W. Bion em termos de modelo. Trata-se de articular a concepção meltzeriana da transferência com o enfoque estético – que percorre toda a obra do autor –, para chegar a propor um possível modelo estético da mente. A partir da idéia de que toda teoria sempre cresce a partir dos obstáculos que encontra, são revisadas as possíveis dificuldades na operatória do modelo kleiniano-teológico, que possam ter se constituído em pontos de partida para o novo modelo proposto. Este modelo estético teria um conceito específico de verdade e, além disso, geraria conseqüências na forma de trabalhar na prática psicanalítica, tais como o estilo de interpretação, baseado fundamentalmente na possibilidade de observar e descrever, assim como também no conteúdo das mesmas.
Priapismo X falicismo (aproximação & diferenças)
Authors: Francischelli Leonardo Adalberto
Published: July 2023

O texto, basicamente, procura introduzir uma discussão em torno da sexualidade masculina partindo da idéia de um fantasma universal representado pelo “priapismo”.
Encruzilhadas e horizontes da psicanálise contemporânea
Authors: Urribarri Fernando , Goijman Leonardo , Saidon Osvaldo , Merea César
Published: July 2023

Buscando ampliar em cada nova edição o intercâmbio com colegas nacionais e internacionais assim como oferecer aos nossos leitores o que há de mais atual no desenvolvimento do pensamento psicanalítico, este Diálogo trata de uma discussão que a cada dia se amplia, inclusive na própria IPA. Pela sua importância, contamos com Fernando Urribarri que escreveu sua introdução, especialmente para a Revista Psicanálise, da SBPdePA. A ele nosso agradecimento. [...]
Extent of piriform cortex resection in children with temporal lobe epilepsy
Authors: Piper Rory J. , Dasgupta Debayan , Eriksson Maria H. , Ripart Mathilde , Moosa Almira , Chari Aswin , Seunarine Kiran K. , Clark Chris A. , Duncan John S. , Carmichael David W. , Tisdall Martin M. , Baldeweg Torsten
Published: July 2023

Objective

A greater extent of resection of the temporal portion of the piriform cortex (PC) has been shown to be associated with higher likelihood of seizure freedom in adults undergoing anterior temporal lobe resection (ATLR) for drug‐resistant temporal lobe epilepsy (TLE). There have been no such studies in children, therefore this study aimed to investigate this association in a pediatric cohort.

Methods

A retrospective, neuroimaging cohort study of children with TLE who underwent ATLR between 2012 and 2021 was undertaken. The PC, hippocampal and amygdala volumes were measured on the preoperative and postoperative T1‐weighted MRI. Using these volumes, the extent of resection per region was compared between the seizure‐free and not seizure‐free groups.

Results

In 50 children (median age 9.5 years) there was no significant difference between the extent of resection of the temporal PC in the seizure‐free (median = 50%,n = 33/50) versus not seizure‐free (median = 40%,n = 17/50) groups (p = 0.26). In a sub‐group of 19 with ipsilateral hippocampal atrophy (quantitatively defined by ipsilateral‐to‐contralateral asymmetry), the median extent of temporal PC resection was greater in children who were seizure‐free (53%) versus those not seizure‐free (19%) (p = 0.009).

Interpretation

This is the first study demonstrating that, in children with TLE and hippocampal atrophy, more extensive temporal PC resection is associated with a greater chance of seizure freedom—compatible with an adult series in which 85% of patients had hippocampal sclerosis. In a combined group of children with and without hippocampal atrophy, the extent of PC resection was not associated with seizure outcome, suggesting different epileptogenic networks within this cohort.
Pseudo‐Ferroelectric Domain‐Wall in Perovskite Ferroelectric Thin Films
Authors: Song Jian , Gong Mingyu , Tsai Meng‐fu , Ma Youcao , Ma Houyu , Liu Yue , Chu Ying‐hao , Huang Rong , Ouyang Jun , Wang Jian , Fan Tongxiang
Published: July 2023

Perovskite ferroelectric thin films exhibit unique dielectric and piezoelectric properties owing to their internal polarized domains that accommodate the out‐of‐plane (ferroelectric) and in‐plane (ferroelastic) polarization‐induced electrostatic and elastic energy. These domains are generally treated as 2D defects with distinctive differences in domain morphology and domain‐wall characteristics, although they are indeed 3D volumetric defects. Here, by using atomistic simulation and microscopy characterization, a “pseudo‐ferroelectric domain” that has the morphology similar to a ferroelectric domain but holds the same defect character of ferroelastic domain‐wall, i.e., semi‐coherent (100)matrix||(100)domain interface is identified. Such pseudo‐ferroelectric domain walls will play a critical role in the migration kinetics of ferroelastic domains and in the piezoelectric responses of ferroelectric thin films during cyclic mechanical/electrical loading. The study throws light on a novel aspect of domains, namely, the 3D configuration and mobility of domain walls, and their role in the overall domain engineering.
Incommensurate Magnetic Order in Hole‐Doped Infinite‐Layer Nickelate Superconductors due to Competing Magnetic Interactions
Authors: Zhang Yajun , He Xu , Zhang Jingtong , Wang Jie , Ghosez Philippe
Published: July 2023

The discovery of superconductivity in hole‐doped infinite‐layer nickelates has fueled intense research to identify the critical factor responsible for high‐Tc superconductivity. Magnetism and superconductivity are closely entangled, and elucidating the magnetic interactions in hole‐doped nickelates is critical for understanding the pairing mechanism. Here, these calculations based on the generalized Bloch theorem (GBT) and magnetic force theorem (MFT) consistently reveal that hole doping stabilizes an incommensurate (IC) spin state and increases the IC wave vector continuously, in a way strikingly similar to hole‐doped cuprates. Going further, a nonlinear Heisenberg model including first‐neighbor and third‐neighbor in‐plane magnetic interactions is developed. The analytical solutions successfully reproduce GBT and MFT results and reveal that the competition between the two magnetic interactions is the decisive factor for the IC magnetic transition. Eventually, by analyzing the doping‐controlled spin splitting of band and orbital‐contributed exchange interactions, direct links between hole doping, magnetization, exchange constants, and magnetic order are established. This discovery of the IC spin state, new understanding of its electronic origin, and establishment of direct connection with the paring electrons radically change the current understanding of the magnetic properties in hole‐doped NdNiO2 and open new perspectives for the superconducting mechanism in nickelates superconductors.
Photo‐ and Redox‐Regulated Transmembrane Ion Transporters
Authors: Ahmad Manzoor , Gartland Shaun A. , Langton Matthew J.
Published: July 2023

Synthetic supramolecular ion transporters find applications as potential therapeutics and as tools for engineering functional membranes. Stimuli‐responsive systems enable external control over transport, which is necessary for targeted activation. The Minireview provides an overview of current approaches to developing stimuli‐responsive ion transport systems, including channels and mobile carriers, that can be controlled using photo or redox inputs.
Assessing the potential of Chios natural mastic for the production of sustainable epoxy composite adhesives
Authors: Anastasiou Dimitrios E.
Published: July 2023

The self‐curable epoxidized polymeric fraction of the natural gum “Chios mastic” (Pistacia lentiscus L.) gum is used as a matrix to produce sustainable particulate composite adhesives and further to manufacture lap joints. Olive pit powder and cotton flocks are used as reinforcements, each for a range of contents. Mixed‐modulus‐joint and Nanotube‐coated‐adherend special manufacturing techniques are also applied to further improve shear properties, reduce shear stress concentrations, or increase the adhesive and the adherend cohesion. 2% (w/w) Aluminum and 2% (w/w) olive pit reinforcements achieve an increase in shear strength of 14.19% and 12.26%, respectively, while cotton flocks‐ initially of lower performance as well as pieces of cotton fabric, are used to make joints according to the Nanotube‐coated‐adherend technique achieving an increase in shear strength of 102.1% and 84.91%, respectively. The obtained experimental results demonstrate the potential of the epoxidized polymer fraction of Chios natural mastic to produce useful sustainable particulate epoxy composite adhesives and double‐sided adhesive tapes.
Challenges and current advances in in vitro biofilm characterization
Authors: Zhang Ye , Young Paul , Traini Daniela , Li Ming , Ong Hui Xin , Cheng Shaokoon
Published: July 2023

Biofilms are structured communities of bacterial cells encased in a self‐produced polymeric matrix, which develop over time and exhibit temporal responses to stimuli from internal biological processes or external environmental changes. They can be detrimental, threatening public health and causing economic loss, while they also play beneficial roles in ecosystem health, biotechnology processes, and industrial settings. Biofilms express extreme heterogeneity in their physical properties and structural composition, resulting in critical challenges in understanding them comprehensively. The lack of detailed knowledge of biofilms and their phenotypes has deterred significant progress in developing strategies to control their negative impacts and take advantage of their beneficial applications. A range of in vitro models and characterization tools have been developed and used to study biofilm growth and, specifically, to investigate the impact of environmental and growth factors on their development. This review article discusses the existing knowledge of biofilm properties and explains how external factors, such as flow condition, surface, interface, and host factor, may impact biofilm growth. The limitations of current tools, techniques, and in vitro models that are currently used for biofilms are also presented.
Four Slip‐Stacked Arrangements, Three Types of Photophysics: Crystal Structure and Solid‐State Fluorescence of 3,6‐Diaryl Substituted Furo[3,4‐c]furanone Polymorphs and Regioisomers
Authors: Pauk Karel , Luňák Stanislav , Machalický Oldřich , Perdih Franc , Vyňuchal Jan , Eliáš Zdeněk , Imramovský Aleš
Published: July 2023

Six symmetrical 3,6‐diaryl (aryl=phenyl, 2‐, 3‐ and 4‐tolyl, 2,4‐ and 3,5‐xylyl) substituted furo[3,4‐c]furanones (DFF) were synthesized. The computational analysis, based on density functional theory, found eight possible centrosymmetrical slipped π‐stack arrangements, formed according to electron repulsion minimization principle, as for previously reported for π‐isoelectronic diketopyrrolopyrroles (DPP). One of these slipped stack arrangements was found to form infinite columns in the crystals of a new polymorph of parent phenyl derivative (with centre‐to‐centre distance CC=6.975 Å), other three types of stacks were found for 3‐tolyl (CC=6.153 Å), 4‐tolyl (CC=3.849 Å) and 2,4‐xylyl (CC=4.856 Å) derivatives by single crystal X‐ray diffractometry. All six derivatives show intense solution fluorescence in blue/green region, with a maximum driven entirely by a number and position of methyl substituents on phenyl rings. On the other hand, the solid‐state fluorescence from yellow over orange to red is observed only for four derivatives and its presence/absence, spectral position and vibronic structure is driven exclusively by the slips in π‐stacks (with interplanar distance always less than 3.5 Å) of almost planar DFF molecules, resulting in J‐type emission, H‐type excimer‐like emission and H‐type quenching.
Portable thermal scanners to detect and monitor small endotherms: A comparative assessment of available equipment to guide practitioners
Authors: Dawlings Finella M. E. , Mackay Claire , Humphrey Morgan , Mitchell William F. , Sorrell Karina J. , Sanchez Sonia , Viola Benjamin M. , Clarke Rohan H.
Published: July 2023

Detection is essential to studying and monitoring wild animals; however, detection is challenging for small endotherms that are nocturnal or best detected at night. Techniques such as trapping or spotlighting disturb focal species, and the effectiveness of spotlighting can be limited for cryptic species, resulting in low detection rates that hinder our ability to monitor and study some endotherms at night. Thermal scanners detect infrared wavelengths not otherwise visible to humans. With improvements in equipment size and cost, thermal scanners have emerged as a valuable tool for passive detection of endotherms. Here we seek to provide objective guidance on thermal tool selection to practitioners who wish to adopt such tools to detect and monitor small endotherms. We compared the efficacy of three handheld thermal scanners (of varying resolutions) and a traditional spotlight for detecting small, cryptic endotherms at night. Random arrays of artificially heated small bird models (representing small, cryptic endotherms) were established along transects in native grasslands that support a range of small threatened endotherms, including the Critically Endangered Plains‐wanderer (Pedionomus torquatus). Transects were independently surveyed by five observers, blind to model locations and model density. Performance measures representing detection capability were assessed for all devices, and usability of each device was assessed with a survey completed by all observers. Detection rates, detection distances, and survey accuracy were greater for thermal scanners with resolutions of 320 × 240 and 640 × 480 than for the spotlight. A low‐resolution thermal scope (160 × 120) performed poorly for all performance measures. There was a consensus among users that a video camera‐style thermal scanner was most comfortable to hold and view while traversing the transect, as opposed to thermal scopes where users look directly through the lens. These results suggest that high‐resolution thermal scanners (≥320 × 240) provide improved detection capabilities compared to traditional spotlights. Higher detection rates provide opportunities for detecting and monitoring small endotherms at night where this was once difficult or impossible.
Soil microbiomes of hardwood‐ versus pine‐dominated stands: Linkage with overstory species
Authors: Gilliam Frank S. , Hargis Elizabeth A. , Rabinowitz Sarah K. , Davis Brenton C. , Sweet Leo L. , Moss Joseph A.
Published: July 2023

Biodiversity in forest ecosystems is paradoxical. Whereas their most apparent component—the woody overstory—is the least diverse with respect to numbers of species, the least apparent component is the biotic community of highest diversity—the soil microbiome. Numerous factors influence the composition and diversity of soil microbial communities, which in turn exert a profound impact on plant species occupying the soil and the biogeochemistry of essential plant nutrients. Of interest in forest ecosystems is how the soil microbiome interacts with the overstory, a phenomenon referred to as linkage. This study compared the soil microbiome of two adjacent stand types—hardwood‐ and longleaf pine (Pinus palustris)‐dominated—and addressed the following questions: (1) How does soil microbiome vary with stand type? (2) Do the forest overstory community and soil microbiome exhibit linkage? Twelve 0.04‐ha circular plots were established in each stand type to assess tree community composition and structure and to sample mineral soil for three separate analyses: assessment of soil fertility, measurement of total carbon and nitrogen (N), and extraction of genomic DNA for assessment of microbiome communities. All live stems ≥2.5 cm dbh in each plot were identified to species and measured for dbh to the nearest 0.1 cm. Mineral soil was taken from a depth of 5 cm and oven‐dried at 38°C prior to analyses. Hardwood stands were dominated by flowering magnolia (Magnolia grandiflora) and southern evergreen oaks, whereas pine stands were dominated by longleaf pine and live oak (Quercus virginiana). Although soils of both stand types were highly acidic, the hardwood stands were generally higher in fertility, especially for total and available N. The overstory and soil microbial communities exhibited evidence of linkage among all sample plots combined. When assessed separately by stand type, only hardwood‐dominated stands displayed evidence of overstory/microbial linkage. These results have broader implications for future scenarios given the sensitivity of soil microbes to climate change.
Energy dissipation mechanisms in three‐dimensional rocking motion of cylindrical structures
Authors: Zhou Xun , Shen Yu , Li Jianzhong , Wang Xiaowei
Published: July 2023

In recent years, there has been a growing recognition that the rocking motion of structures, especially cylindrical ones, should be evaluated with three‐dimensional (3D) models. However, dissipation mechanisms in 3D models are complex and have yet to be well established. This paper presents an analytical study on an inherent dissipation mechanism based on the rolling friction model and an external dissipation mechanism based on energy dissipators (EDs) for 3D rocking cylindrical structures. Through a variational formulation, the nonlinear equations of motion are derived considering the rolling friction model and the Bouc–Wen model. Compared with the existing inherent dissipation model in literature, the rolling friction model has a noticeable advantage that it can capture the energy dissipation behavior during free vibration under various initial conditions. Additionally, the rolling friction model is more versatile since the contact coefficient is adjustable. On the other hand, external EDs further enhance the energy dissipation of the structures. Roles of the inherent and external mechanisms in the 3D rocking motion of cylindrical structures against earthquakes are assessed using a series of near‐fault pulse‐like ground motions. Results indicate the inherent dissipation mechanism, that is, the rolling friction model, cannot avoid overturning under near‐fault pulse‐like ground motions, leading to unstable structures. This is because an uplifted cylinder will continuously absorb energy from earthquake excitations, while the amount of energy dissipated by the rolling friction model is small. Comparatively, adding external EDs is effective in mitigating seismic responses and thereby avoiding overturning.
Resilience in children and youth in street situations in León, Nicaragua
Authors: Hamel Kayla , Bohr Yvonne
Published: July 2023

There are tens of millions of children and youth in street situations (CYSS) worldwide, the majority of whom are males living in low‐ and middle‐income countries. Many of these children demonstrate impressive adaptability and resilience. The focus of the current research was on the resilience of male CYSS in León, Nicaragua. Qualitative data were collected through individual interviews and focus groups with CYSS, their family members, community members, and staff of a local nonprofit, with the objective of exploring and consolidating local understandings of resilience. Grounded theory analysis of qualitative data yielded a context‐specific conceptual model of resilience as it pertains to CYSS in León. Six qualities were identified to represent the experience of resilience in this group: agency, belonging, flexibility, protection, self‐regulation, and self‐worth. The knowledge generated from this research can serve as a foundation to develop and implement resilience‐promoting interventions for CYSS.
Lipopolysaccharide impairs neurodevelopment and induces changes in astroglial reactivity, antioxidant defenses and bioenergetics in the cerebral cortex of neonatal rats
Authors: Rojas Denise Bertin , Vizuete Adriana Fernanda K. , de Andrade Vivian Strassburger , de Andrade Rodrigo Binkowski , Gemelli Tanise , Kim Tomas Duk Hwa , Gonçalves Carlos Alberto , Leipnitz Guilhian , Wannmacher Clovis Milton Duval
Published: July 2023

Neonates have an immature immune system, which increases their vulnerability to infectious agents and inflammatory insults. The administration of the immunostimulatory agent lipopolysaccharide (LPS) has been shown to induce the expression of pro‐inflammatory cytokines and cause behavior alterations in rodents at different ages. However, the effects of LPS administration during the neonatal period and its consequences during immune system maturation remain to be elucidated. We showed here that a single intraperitoneal administration of LPS in rats on postnatal day (PND) 7 caused early and variable alterations in TNF‐α, S100B and GFAP levels in the cerebral cortex, CSF and serum of the animals, indicating long‐term induction of neuroinflammation and astroglial reactivity. However, on PND 21, only GFAP levels were increased by LPS. Additionally, LPS induced oxidative stress and altered energy metabolism enzymes in the cerebral cortex on PND 21, and caused neurodevelopment impairment over time. These data suggest that neuroinflammation induction during the neonatal period induces glial reactivity, oxidative stress and bioenergetic disruption that may lead to neurodevelopment impairment and cognitive deficit in adult life.
Editorial for “Remodeling in Aortic Stenosis With Reduced and Preserved Ejection Fraction: Insight on Motion Abnormality Via 3D+Time Personalized LV Modelling in Cardiac MRI”
Authors: Guo Yin , Akcicek Ebru Yaman , Yuan Chun
Published: July 2023

Level of Evidence

5

Technical Efficacy Stage

2