bluuebunny/crossref_metadata_2025 huggingface dataset:
THE APPLICATION OF CELL-FREE FETAL DNA (cff-DNA) AND SIBLINGS DNA METHODS IN THE PROCESS OF PATERNITY TEST THROUGH CODIS STR LOCI (CSF1PO, THO1, TPOX, AND vWA)
Authors: Yudianto Ahmad , Kurniawan Arofi , Koesbardiati Toetik , Faisol Achmad , Setiawan Fery , Furqoni Abdul Hadi , Fauziah Yessi Andriani
Published: January 2022

Background: The non-invasive cff-DNA and siblings DNA methods are the latest breakthroughs in the forensic identification process. The use of cff-DNA and siblings DNA as non-invasive techniques in the forensic identification process has, hitherto, not been widely proven. Methods and Materials: This was an analytic observational study. The sample of this study consisted of peripheral blood of women in the second trimester of pregnancy and their two biological children. The kinship analysis was carried out through siblings' DNA and cff-DNA from the mothers through CODIS STR loci (CSF1PO, THO1, TPOX, and vWA). Results: The means of allele sharing between full siblings in loci CSF1PO, THO1, TPOX, and vWA were 0 (13.75%), 1 (44.75%), and 2 (41.50%). The allele sharing found in the study is in line with the one in previous research conducted by Wenk (1998) and the theory proposed by O'Connor (2011), indicating that one allele sharing dominates, contrasting with the finding of previous research conducted by Sosiawan (2020) revealing that 2-allele sharing was more superior. The variation is caused by the ethnicity having a different genetic contribution among the population. The variation can be attributed to historical and demographical processes leading to genetic drift. Conclusion: The mean of SI in 1 allele sharing in CODIS STR loci (CSF1PO, THO1, TPOX, and vWA) has the highest value of 44.5%. The use of cff-DNA of pregnant women as one of the non-invasive techniques can serve as an alternative material in a paternity test.
Persepsi Orang Tua terhadap Pembelajaran Musik Selama Pandemi COVID-19
Authors: Mulyasari Sinta , Fitroh Siti Fadjryana , Oktavianingsih Eka
Published: January 2022

Pembelajaran musik akan mengoptimalkan pertumbuhan dan perkembangan anak, adanya persepsi positif orang tua akan memberikan kelancaran pada pembelajaran musik. Namun, yang terjadi di lapangan sebagian besar anak lebih suka mendengarkan lagu orang dewasa, kurangnya pemberian waktu mengeksplore bermain musik serta belajar jarak jauh memberikan kendala kepada orang tua. Penelitian ini memiliki tujuan untuk mengetahui persepsi orang tua terhadap pembelajaran musik selama pandemi Covid-19. Penelitian ini menggunakan penelitian kuantitatif deskriptif dengan menggunakan uji normalitas dan analisis statistika deskriptif. Tujuan uji normalitas untuk mengetahui normal tidaknya suatu distribusi data. Subjek penelitian ini merupakan orang tua di PAUD Anna Husada Bangkalan sebanyak 17 orang tua yang dijadikan sampel.Teknik pengambilan sampel menggunakan sampling jenuh. Teknik pengumpulan data menggunakan kuesioner. Hasil yang diperoleh dari uji normalitas adalah nilai 0,534 0,05. Sehingga Ho diterima dan Ha ditolak. Analisis data tersebut menunjukkan persepsi orang tua terhadap pembelajaran musik di PAUD Anna Husada Bangkalan selama pandemi Covid-19 cenderung mendukung. Orang tua memberikan pendampingan belajar kepada anak serta bekerja sama yang baik dengan pihak sekolah.
Pengembangan Nominal Aturan Fuzzy pada Metode Fuzzy Mamdani untuk Menyeimbangkan Beban Tiga Phasa pada Saluran Distribusi Tegangan Menengah
Authors: Djagolado Martinus W , Amirullah Amirullah , Saidah Saidah
Published: January 2022

The use of electrical equipment on the customer side with low voltage absorbs unbalanced power. The load unbalances in each phase will result in an unbalanced current, resulting in a phase voltage shift in the secondary coil of the 20 kV/380 V medium voltage transformer. Shifting the voltage in the distribution transformer phase, then causes the flow of current in the transformer neutral wire causing losses. This paper proposes a fuzzy logic method with the Mamdani fuzzy inference system (FIS) to balance three-phase load currents at seven feeders of 20 kV medium voltage distribution at PLN Rayon Taman Jawa-Timur. The feeders are Ngelom, Tawang Sari, Geluran, Bringin, Masangan Kulon, Palm Residence, and Pasar Sepanjang. There are three input variables used, namely the load current in phase R, phase S, and phase T respectively. There are three output variables in one FIS block, namely changes in load current in phase R, phase S, and phase T respectively. With the number of fuzzy rules as many as 509 rules, the proposed method is able to produce the lowest load current unbalance value of 1.6% at Palm Residence Feeders. The development of a nominal (number) of fuzzy rules in the Fuzzy Logic Method with FIS Mamdani is able to reduce the value of unbalance load current at the 20 kV medium voltage distribution feeder better than the method proposed by previous researchers.
Analisis Pengaruh Faktor Kinerja Terhadap Produktivitas dan Optimasi Dinas Pembekalan TNI AL
Authors: Masriansyah Masriansyah , Purnomo Untung , Sirait Binsar Mangaratua
Published: January 2022

The Navy Debriefing Service is a central implementing agency whose main task is a series of supply chain management, which has several problems related to the uneven competence of Disbekal personnel, limited human resources and lack of creation, innovation, improvisation, as a result of the large number of personnel who have been around for a long time. served in Disbekal. So the purpose of this research is to analyze the influence of competence and the influence of organizational culture partially on the work productivity of Disbekal. As well as analyzing the influence of competence and organizational culture simultaneously on the work productivity of Disbekal. Descriptive verification research method with data analysis techniques using Path Analysis. The number of samples is 88 personnel, with data collection through stratified random sampling. The results showed that there was a significant influence between competence, and organizational culture on the work productivity of the TNI AL debriefing service partially and simultaneously. Where the direct influence of the competence variable is 30.2%, and the organizational culture variable is 18.5%. The total effect is 68.1% overall, while 39.1% is the influence of other factors that were not researched.
Effects of Dietary Salt-Based Minerals and Phosphorus Supplements on Mean Body Weight, Survival Rate and Feed Conversion Ratio of White Shrimp Reared In Brackish Water
Authors: Amir Nizar , Efendy Makhfud , Hidayat Agriananta Fahmi
Published: January 2022

This study aimed to examine the impact of dietary salt-based mineral and phosphorus supplements on mean body weight, survival rate, and feed conversion ratio of Litopenaeus vannamei (white shrimp) reared in brackish water. The experiment was performed randomized design with three replicates in each treatment used twelve 40 L rectangular polymethyl methacrylate containers reared 45 days. The four treatments in this study were based on the concentration of salt-based mineral and phosphorus supplements (control or 0 ppm, one ppm, two ppm, and three ppm) in dietary of white shrimp. The results showed that using salt-based mineral and phosphorus supplements in dietary of white shrimp positively impacts mean body weight, survival rate, and feed conversion ratio. Increasing the concentration of salt-based mineral and phosphorus supplements increased mean body weight and survival rate and reduced feed conversion ratio of white shrimp. The mean body weight, survival rate, and feed conversion ratio of white shrimp were achieved with three ppm of dietary salt-based mineral, and phosphorus supplements reared 45 days was 5.98 gr, 88.57%, and 1.45, respectively.
Review Strategis Upaya Pengamanan Laut Nasional Menuju Keamanan Maritim dan Pengelolaan Ruang Laut Indonesia
Authors: Suharyo Okol Sri , Bastari Avando
Published: January 2022

The Republic of Indonesia as a world maritime country and an archipelagic country which has 17,504 islands whose territorial area is dominated by the ocean. As a maritime country, Indonesia has 4 (four) points that become international chokepoints, namely the Malacca Strait, Sunda Strait, Lombok Strait and the Ombai-Wetar Strait. Indonesia has established three Indonesian Archipelagic Sea Lanes (ALKI) for the peaceful passage of international shipping, which are guaranteed by international and national law. The Indonesian Maritime Security Agency is a Non-Ministerial State Institution whose position is under and directly responsible to the President and has the authority to enforce the law at sea and is justified by law, so that with the issuance of Law Number 32 of 2014 concerning Marine Affairs and Presidential Regulation Number 178 of 2014 concerning the Indonesian Maritime Security Agency, it can be interpreted that there is legal legitimacy for the Indonesian Maritime Security Agency in carrying out its duties, functions and authorities to carry out law enforcement against special crimes at sea. This study aims to explore Indonesia's strategic role in law enforcement at sea towards national maritime security and resilience. The method used is a literature study approach and the data analysis technique used is a qualitative data approach by conducting secondary data analysis to explain the findings obtained. This research produces findings in the form of an analysis of Indonesia's strategic role in law enforcement at sea towards maritime resilience and security both nationally and regionally.
Comparative analysis of Sri Aurobindo Ghosh, Jalaliddin Rumi and Henri Bergson’s ideas about intuition and spiritual love
Authors:   National University of Uzbekistan named after Mirzo Ulugbek, Kabulniyazova Gulchehra T.
Published: January 2022

The article analyzes the ideas of the Sufi thinker, poet Jalaladdin Rumi, the prominent Indian philosopher Sri Aurobindo Ghosh, and Henri Bergson about intuition and spiritual love. These thinkers, who lived in different historical eras, who were not familiar with each other’s creativity, expressed a number of similar ideas. These are ideas of spiritual love and intuition. According to Rumi, the idea of a person as God’s slave or servant is significantly lower than the idea of a person as a beloved of God, since it prevents one from seeing the im­age of God in the inner world of a person; the enlightened human soul strives to merge with the world soul. The highest goal of the integral yoga of Aurobindo is the unity of body, soul and spirit, thanks to which a latent spiritual force with a divine nature manifests itself in a person, a person turns into an instrument of action of divine will – Shakti. Rumi sees the meaning of human life in the dis­closure of creative abilities. Bergson defines intuition as the energy of benevo­lence, with the help of which the intellectual limitations of people are over­come. A person, according to Bergson, is a creative being, in whose activity a creative impulse is manifested; in turn, this impulse gives rise to intuition. Comparing the views of three thinkers, we find a pantheistic attitude that makes different worldviews comparable and provides a basis for their comparative study, which was pointed out in the 11th century. outstanding Central Asian en­cyclopedist Abu Rayhan al-Biruni. In our opinion, the ideas of spiritual love and intuition are the bridge that connects Western and Eastern cultures, which are very different from each other.
The Transformative Role of Crisis in the Context of Contemporary Anthropological Problems
Authors:   Institute of Philosophy, Russian Academy of Sciences, Kiyashchenko Larisa P.
Published: January 2022

The focus of consideration of human transformation sets up optics to track multi­ple configurations in the formation of its modern forms at the intersection be­tween realities from heterogeneous areas – the logic of the polysemy of the hu­man identity crisis. Identity configurators mediate, for example, between an inter-element macrophysical order greater than the resulting individual and an intra-element microphysical order smaller than that individual (G. Simondon) Or the relationship between the transcendent and the immanent, forming the ex­perience of transdisciplinarity (Ya. Svirsky). This mediation between the ultimate (contradictory, conflicting, contrasting) realities (events, situations) is the begin­ning of the formation (individuation) of a particular individual. Such a vision raises questions. Does the transformation of a person always take place against the background of crisis phenomena similar to the modern crisis of technological civilization, which are manifested in the relationship of a person between his ex­ternal and internal nature? And what, then, do we mean by conceptualizing the term crisis? The article attempts to show the crisis as a converter of the course of evolution of the biosocial nature of man. The conceptualization of the term crisis is formed through the grasping of a variety of ambivalent semantic interpreta­tions, which are guessed in the situational analysis of the case studie, between the judgments about the essence and existence of modern man in his ontological presuppositions.
The Myth of Science as a Source of Progress
Authors:   Institute of Philosophy, Russian Academy of Sciences, Kasavina Ilya T. ,   Lobachevsky State University of Nizhni Novgorod
Published: January 2022

In the philosophy of science and technology, scientific progress has been usually considered in a logical-methodological way, namely, from the point of view of the capacity to solve problems, the theoretical and empirical success of a certain theory or scientific research program. These are the concepts of K. Popper, I. Lakatos, and L. Laudan. They are opposed by historical and sociological ap­proaches to the development of science by T. Kuhn, S. Toulmin, and P. Feyer­abend. The article proposes a variant of the second approach – socio-epistemo­logical and, in particular, value interpretation of scientific progress shifting the focus of the discourse on scientific progress to the world-view and ideological circumstances of the development of science not only as knowledge, but as a form of culture and social institution. There is a polemic with the thesis by A.L. Nikiforov about the dominant pragmatic need for science and the primacy of its applied results, as ifthe modern achievement of which science has al­legedly fulfilled as well as the purpose prescribed to it by F. Bacon, and even ex­hausted its progressive potential. Criticism of the position by A.L. Nikiforov is based on an alternative view on science, which follows from a different interpre­tation of the New Times scientific revolution and the purpose of science in gen­eral. Scientific progress is seen in the creation by science of a new image of the world, new ways of communication, new moral guidelines, the design of new ways of social order. Such a science does not fit into the narrow, logical-method­ological criteria of scientific rationality. However, it is precisely this culture-forming, socio-cultural function of science that allows us to talk about science as an enterprise that contributes to social progress and, if progressive, it is precisely because of this circumstance.
The Pandemic: During and After
Authors:   Institute of Philosophy, Russian Academy of Sciences, Fedotova Valentina G.
Published: January 2022

The article examines the coronavirus pandemic from the standpoint of the social construction of reality. In the first part, the author discusses the similarity of the socio-cultural aspects of the modern pandemic and its manifestations in the past, referring to the characteristics of the epidemics that occurred earlier in the his­tory, described by the Russian-American sociologist P. Sorokin. The article shows how the universal and specific features of social disasters, in particular epidemics, and the pandemics in our time, form the policy of rescue. The second part of the article is devoted to forecasting the post-pandemic future. The author highlights different types of forecasting the future in discussions about the post-pandemic life and in social practices. The article provides forecasts of the future put forward by well-known experts at the beginning of the pandemic. The main idea of the forecasts is that the world will never be the same again, which the author considers a characteristic of the type of constructing the future through a rather radical break with the past. The author believes that the modus of fore­casting according to the “break with the past” model rather characterizes not the future itself, but the peculiarity of the pandemic discourse, the essential feature of which is the desire to establish the border of the pandemic through symbolic separation from the crisis situation of the present. Another less common option for constructing the future is the “back to the past” format, where the pre-pan­demic past is the norm. The author believes that the most likely scenario for the future after a pandemic will be the coexistence and layering of elements of the old and the new in multiple forms of their interaction and hybridization.
Duality of F.M. Dostoevsky: Russia and Europe in the “Diary of a Writer”
Authors:   National Research University Higher School of Economics, Kiseleva Marina S.
Published: January 2022

The author examines the phenomenon of duality in the “Diary of a Writer” in the historical context and in the actual Russian journalism of the 70s. XIX century. The double idea of Dostoevsky as the basis of the metaphysical depths connects the literary and philosophical analysis of his prose. The author shows that the phenomenon of duality has an existential basis in the writer’s bi­ography: his experience of being sentenced to death, then replaced by Siberian penal servitude; after his release, he traveled to Europe and returned to St. Pe­tersburg. The “inner soil” of duality, personally experienced and requiring the writer to comprehend, took shape by the mid-70s. as an idea of Russia’s closest leadership among European countries. Criticizing bourgeois Europe, Dosto­evsky was sure that Russia will always need European culture. The phenome­non of duality is shown in Dostoevsky’s construction of a double composition of his “Diary”, as well as in the “conversational” basis of the text, built on the letters of readers and used by the writer in an internal dialogue with both the reader and himself, also in the language markers “we” and “they”. The problem of Russian-European “double” ties runs through the entire journalism of Dosto­evsky, defining his historiosophical concept, attitude to faith, understanding of the moral choice of man.
The Crisis of Contemporary Culture: A View from the History of Russian Philosophy: (Fedotov – Weidle – Landau – Bicilli) Materials of the “round table”
Authors:   Institute of Philosophy, Russian Academy of Sciences, Pruzhinin Boris I. , Antoshchenko Aleksandr V. ,   Petrozavodsk State University, Galcheva Tanya N. , Golubovich Inna V. ,   Odessa I.I. Mechnikov National University, Gurin Dmitriy V. ,   Immanuel Kant Baltic Federal University, Shchedrina Irina O. ,   National Research University Higher School of Economic, Shchedrina Tatiana G. ,   Institute of Social and Humanitarian Education, Moscow State Pedagogical University, Janzen Wladimir W.
Published: January 2022

On August 26, 2021, with the support of “Voprosy filosofii” was held a “round table”, the participants of which considered it meaningful and relevant to address the legacy of experiencing and philosophical reflection of critical epochs by peo­ple who have fully endured the “breakdown” of being and an anthropological crisis – for comprehending the disturbing changes taking place in modern soci­ety. In this regard, the intellectual biographies of thinkers who felt a colossal shock in the 1920s and who tried to comprehend their local experience as a global are exceptional. In the authors’ focus are ideas and arguments of the philosophers of the Russian Abroad about the crisis of their contemporary culture (Fedotov – Weidle – Landau – Bicilli). The “round table” is an attempt to correlate their experience with the modern reality of the anthropological crisis. The studying intellectuals underlined the death of culture as the main threat to the life of the social organism. The salvation of culture, first of all, depends on the spiritual efforts of people. From this point of view, philosophy has to com­prehend the principles that make it possible to resist the processes of cultural de­struction. And in this regard, the personality of the philosopher is of exceptional importance, his willingness to live and work “as if history would never end, and at the same time, as if it ended today” (G.P. Fedotov). The philosophy of culture forms the ideal of personal choice as a free submission to universal human goals. The relevance of the intellectual and spiritual search of the “Russian Abroad” thinkers can't be overestimated since this crisis continues today, entering ever new, previously unpredictable phases. The struggle for culture continues. There­fore, the intellectual searches of the "Russian Abroad" thinkers are essential to­day. The core of the discussions was three actual topics in the context of their comprehension by the philosophers: 1. The crisis of religious consciousness; 2. The crisis of scientific rationality; 3. Crisis of cultural identity.
Social Sciences Today: Contemporary Challenges
Authors:   Moscow State Institute of International Relations, Fedotova Nadezhda N.
Published: January 2022

The article highlights several areas that pose challenges for social science today. One of the challenges is the study of culture. The evolution of interest in culture in the social sciences is traced through an appeal to the role of culture in eco­nomics, which was an ideal type of ignoring culture for the most part of the 20th century. A paradigmatic shift towards interest in the study of culture at the turn of the 20th and the 21st centuries temporarily expelled society from the main forces that determine human behavior. This approach is no less reductionist than the previous expulsion of culture. The growing attention to the role of culture somewhat obscures the discussion of the problems caused by the spread of global capitalism and the development of digital technologies. Several other challenges stem from the changes in the internal and external contexts of social knowledge production. In our opinion, the idea of human rights is becoming a new significant context both for discussing the challenges of digitalization, and external challenges to science. The author maintains the right to one’s own knowledge and public expression of judgment, to some extent reduces the grow­ing restrictions in other areas of the human rights exercise.
Intellectual Responsibility and Epistemological Theism
Authors:   HSE University, Ugleva Anastasia V.
Published: January 2022

One of the most interesting and widely discussed trends in modern epistemology is the so-called intellectual ethics, normative in its essence, centered around the concept of epistemic virtue, based on the idea of metaphysical anthropology, supplemented by elements of theology. The last consists in the idea of a certain “gift” to a person from the side of the Supreme Being, which is God – and this gift lies in the epistemic virtues inherent in the individual. This subject-centered concept emphasizes the intellectual and epistemic qualities of the cognizing subject that guarantee the truth of their beliefs. However, if is God the true guarantor of their “epistemic reliability” and the possibility of thus identifying justified belief with knowledge? The reliability of the cognitive human ability is seen in the realization of virtus as “perfection in being for the good”, in this case epistemic, the only guarantee of which can only be divine will. Is it so? This article attempts to answer this question in the course of reconstruction and analysis of the epistemological-theistic approach to defining one of the key epistemic virtues of the cognizing subject – intellectual responsibility.
The Phenomenon of Complexity and Quantum Semiotics
Authors:   Institute of Philosophy, Russian Academy of Sciences, Arshinov Vladimir I. , Budanov Vladimir G. ,   Institute of Philosophy, Russian Academy of Sciences
Published: January 2022

The article is devoted to the discussion of some characteristic features of the “complexity paradigm” (Moraine). It is emphasized that thinking in complexity needs an adequate conceptual optics, methodological support, which can be rep­resented by a conceptual assemblage – a heterogeneous perceptual and com­municative network of concepts of quantum mechanics and Peirce semiotics, considered ontogenetically in terms of processality, temporality, becoming. The situation with thinking in complexity is such that this optics should arise as a certain set of cognitive operations as a certain topologically connected set of semiotically meaningful operations in the very process of realizing a cognitive situation as becoming specifically complex. And this awareness is a key prereq­uisite for the emergence of that epistemological situation, which we call “meet­ing with complexity”. Or, more precisely, thinking together with complexity. It is emphasized that the encounter with complexity itself implies the presence of a kind of sensitivity, an intuitive predisposition to its conscious recognition as such. We need such a conceptual character as the “observer of complexity”, un­derstood in the unity of the multiplicity of cybersemiotic, synergetic and quan­tum mechanical perspectives. A character who traces his ancestry from the quan­tum-relativistic physics of the twentieth century and the procedural philosophy of Pierce, Bergson and Whitehead.It is emphasized that in Peirce's scheme there is a specific, context-dependent relationship between signs and objects with which they are connected through the third element, an interpreter that plays the role of a connecting link between them" And this semiotic interpreter of Peirce is, in fact, a semiotic observer-a participant in the becoming turbulent flow of temporal complexity, synergistically included in the self-organizing quantum Universe.
Meaning-constitution Problems in the Digital Culture’s Horizon
Authors:   Institute of Philosophy, Russian Academy of Sciences, Morkina Julia S.
Published: January 2022

Meaning-constitution and creativity processes in contemporary culture have ob­viously been changed under the artificial intelligence’s conditions as “natural-ar­tificial intelligence” system starts to contribute to creativity as meaning-constitu­tion and creativity processes. Аrtificial intelligence seems to be a relatively young actor in the human culture. Its conceptual framing as well as its philo­sophical contribution to meaning-constitution processes requires special research efforts. Search for the new ways of meaning-constitution conceptual framing in conceptual culture’s horizon, is consists of different actors including artificial intelligence facilities, already posed numerous epistemological and ethical prob­lems, is the purpose of the present research. Research strategy and meaning-con­stitution analysis requires to separate meaning-constitution approaches in con­temporary research tradition on micro- and macro-levels. As for micro-level approaches to consciousness are concerned, I arrive to the conclusion, that artifi­cial intelligence contribution in creativity processes requires macro-level ap­proach to contemporary culture. I am trying to analyze artificial intelligence – within the framework of the macro-level approach – as a special actor, sophisti­cated phenomenological contemplations and B. Latur’s actor-network theory be­ing relevant to the study of this subject matter.
The USSR in Its International Aspect: a Philosophical and Historical Analysis of the Ways for Solving Agrarian Question by the Bolsheviks
Authors:   Institute of Philosophy, Russian Academy of Sciences, Niсkolsky Sergey A.
Published: January 2022

The formation of the USSR five years after the October Revolution followed not only from internal needs, but also from the idea of “dialectical transition” of the feudal-capitalist component of the Russian empire’s heritage to the socialist form. The USSR formation also had a more ambitious goal: The Soviet Union was expected to become the first experience of creating the “world workers and peasants union” (V.I. Lenin). First of all, this experience was gained in the agri­cultural sphere – the dominant sector of the country’s economy. In this regard, the main scientific problem of this article is the philosophical and historical un­derstanding of the methods invented by the Bolsheviks during the war commu­nism policy period in 1918–1921 to form a new sense of agrarian life adequate to the future “world USSR”. After a short break of NEP the experience gained in the agrarian sphere was used during the forcible сollectivization in the Russian Federation and in the territories of the former Russian Empire annexed to it for internationalist purposes. The article analyzes in detail the political and ideologi­cal reasons of the Bolshevik’s activities solving the agrarian question during the periods of “war communism” and collectivization, the legal basis they had de­veloped for this issue, the successive elimination of the peasant cooperation as a self-organization of active people, the idea of historical necessity and the com­munist practicability of the overall labor obligation and the effectiveness of forced labor, as well as the consequences of these measures: the terrible famine of 1920–1921 and the armed resistance of the peasantry to the agrarian policy of the Bolsheviks.
Effectiveness Evaluation Method of Constellation Satellite Communication System with Acceptable Consistency and Consensus Under Probability Hesitant Intuitionistic Fuzzy Preference Relationship
Authors: Wang Yanjun , Hu Xiaoxuan , Wang Lidong
Published: January 2022

System effectiveness evaluation is an important part of constellation satellite communication system research, with applications in project verification and optimization as well as tactical and technical measurement argumentation. This paper presents a systematic and comprehensive effectiveness evaluation method for a constellation satellite communication system under a probabilistic hesitant intuitionistic fuzzy preference relationship (PHIFPR), aiming to better address the fuzziness and uncertainty in effectiveness evaluation. First, a proposed definition of PHIFPR describes the hesitancy of evaluators, provides hesitancy distribution information, and depicts the worst negative information and risk preferences in effectiveness evaluation. Then, we deduce the approximate consistency index of PHIFPR and establish a mathematical programming model to increase individual consistency when the approximate consistency index does not reach a predetermined level. In the sequel, a proposed group consensus index uses the PHIFPR-based Hausdorff distance to measure the closeness between evaluators' judgements. Afterwards, a consistency and consensus improvement model is designed to retain the original opinions of evaluators to make the consistency and consensus of PHIFPRs acceptable. Moreover, a goal programming model is established to gain the reliable scheme priority weights by regarding the approximate consistency condition of a PHIFPR as a fuzzy constraint. Finally, an experimental example is offered to highlight the practicability and feasibility of the proposed method, and some comparative analyses with other methods offer insights into the designed method.
Symmetry and Nonexistence of Positive Solutions for a Fractional Laplacion System with Coupled Terms
Authors: Zhang Rong
Published: January 2022

In this paper, we study the problem for a nonlinear elliptic system involving fractional Laplacion: (equation 1.1) where 0 < α, β < 2, p, q > 0 and max{p, q} ≥ 1, α + γ > 0, β + τ > 0, n ≥ 2. First of all, while in the subcritical case, i.e. n + α + γ − p(n − α) − (q + 1)(n − β) > 0, n + β + τ − (p + 1)(n − α) − q(n − β) > 0, we prove the nonexistence of positive solution for the above system in R n . Moreover, though Doubling Lemma to obtain the singularity estimates of the positive solution on bounded domain Ω. In addition, while in the critical case, i.e. n+α+γ −p(n−α)−(q + 1)(n−β) = 0, n+β +τ −(p+ 1)(n−α)−q(n−β) = 0, we show that the positive solution of above system are radical symmetric and decreasing about some point by using the method of Moving planes in Rn Mathematics Subject Classification (2020): 35R11, 35A10, 35B06.
A Black Hole-Aided Deep-Helix Channel Model for DNA
Authors: Sarker Md Abdul Latif , Kader Md Fazlul , Sarker Md Mostafa Kamal , Lee Moon , Han Dong
Published: January 2022

In this article, we present a black-hole-aided deep-helix (bh-dh) channel model to enhance information bound and mitigate a multiple-helix directional issue in Deoxyribonucleic acid (DNA) communications. The recent observations of DNA do not match with Shannon bound due to their multiple-helix directional issue. Hence, we propose a bh-dh channel model in this paper. The proposed bh-dh channel model follows a similar fashion of DNA and enriches the earlier DNA observations as well as achieving a composite like information bound. To do successfully the proposed bh-dh channel model, we first define a black-hole-aided Bernoulli-process and then consider a symmetric bh-dh channel model. After that, the geometric and graphical insight shows the resemblance of the proposed bh-dh channel model in DNA and Galaxy layout. In our exploration, the proposed bh-dh symmetric channel geometrically sketches a deep-pair-ellipse when a deep-pair information bit or digit is distributed in the proposed channel. Furthermore, the proposed channel graphically shapes as a beautiful circulant ring. The ring contains a central-hole, which looks like a central-black-hole of a Galaxy. The coordinates of the inner-ellipses denote a deep-double helix, and the coordinates of the outer-ellipses sketch a deep-parallel strand. Finally, the proposed bh-dh symmetric channel significantly outperforms the traditional binary-symmetric channel and is verified by computer simulations in terms of Shannon entropy and capacity bound.
Unusual Removal of T-DNA in T1 Progenies of Rice after Agrobacterium-mediated CRISPR/Cas9 Editing
Authors: Yang Qin , Tae-Sung Park , Bumkyu Lee , Myung-Ho Lim
Published: January 2022

In the present study, we attempted to knock out the bar gene selection marker in the fixed Bt- and herbicide-resistant transgenic line BT-T07 (T8 generation) to generate a marker-free Bt-resistant rice line. A binary vector containing a CRISPR/Cas9 system targeting the 108–130 bp region of bar was transformed into rice embryonic calli, and plantlets were regenerated under non-selective conditions. Three T0 plants were observed to have non-target point mutations and deletions in the targeted gene and were putatively heterozygous and chimeras. One T0 plant, 130-4, was confirmed to have a 76-nt deletion, from 140 bp to 225 bp, and it showed the segregation of bar in its T1 progenies, with 16 bar-knockout lines and seven normal bar-expressing lines. However, the CRISPR/Cas9 editing vector sequences were not detected in any of the T1 plants. In addition, unusual removal of pre-existing T-DNA was observed in all bar-knockout T1 plants. Illumina sequencing of a bar-knockout line, 130-4-36, revealed a small fraction of read residues of pre-existing T-DNA from the bar sequence to the right border at the original junction site. We speculate that this rare phenomenon might be directed by the homology between pre-existing T-DNA and CRISPR/Cas9 editing vector sequences during meiotic recombination. We report imprecise modifications and unpredictable outcomes of gene-editing techniques, providing valuable perspectives on gene-editing applications.
Evaluation of the Safety and Effectiveness of Tubal Inflammatory Drugs Used in Patients with Incomplete Tubal Obstruction After Four-Dimensional Hysterosalpingo-Contrast-Sonography Examination
Authors: Zhang Yue , Wang Qin , Gao Chun-yan , Tian Hong-ju , He jiao , Zhang Xi , Xiong Xi
Published: January 2022

Background

To investigate the safety and effectiveness of tubal inflammatory drugs in patients with incomplete tubal obstruction of at least 1 side after four-dimensional hysterosalpingo-contrast-sonography (4D-HyCoSy) examination.
Methods

215 cases of tubal insufficiency were diagnosed by ultrasonography from February 2019 to November 2020.According to retrospective analysis,the patients in this study were divided into experimental and control groups; the experimental group was treated with a push of salpingitis drugs, and the control group received blank control. Basic information, degree of pain, postoperative complications, and pregnancy rate were then compared between the 2 groups.
Result(s)

: Compared with the control group, there was no significant difference in the basic information; preoperative, intraoperative, or postoperative pain; or in postoperative complications (P > 0.05). The cumulative pregnancy rate of the experimental group (28.0%) was statistically different from that of the control group (15.3%) (P < 0.05).
Conclusion(s):

We observed that for infertile patients with incomplete obstruction of at least one fallopian tube as diagnosed by contrast-enhanced ultrasonography, salpingitis-treatment drugs effectively improved the pregnancy rate postoperatively, with high effectiveness and safety. This regimen is thus worthy of further investigation and promotion in the future.
Dynamic Two-sided Matching Group Decision-making Model With Multi-form Preference Information for Configuring Tasks and Resources in Cloud Manufacturing
Authors: Zhang Xuejiao , Yang Yu
Published: January 2022

Enterprises have been faced with the problem of how to optimize resource allocation in an uncertain environment by the expanding of manufacturing informatization. In the process of cloud manufacturing matching, group decision making organizations may provide uncertain preference information. However, preference information at various points have led to differing impacts of the final matching decision. it is necessary to study the dynamic two-sided matching. In this paper, the dynamic two-sided matching problem under the multi-form preference information was studied. Primarily, the problem of two-sided matching is described, then through group decision-making and uncertain preference information, an ordinal vector matrix is constructed. Afterwards, the comprehensive satisfaction matrix is calculated by using dynamic time-series weight and matching competition degree. Further, by introducing stable matching constraints, a multi-objective optimization model considering the satisfaction, fairness and stability of matching is constructed. Then the optimal matching result is obtained by solving the model. In addition, the presented method was verified through a case of cloud manufacturing. At the end, advantages of the presented model were demonstrated by comparison. Research results of this paper enrich the theoretical research of two-sided matching and provide an effective solution for cloud manufacturing matching in uncertain environments.
Trend Analysis of Reference Evapotranspiration in the São Francisco River Basin, Brazil
Authors: Silva Neilon , de Oliveira Aureo Silva
Published: January 2022

An important requisite in any water resources management program is the knowledge of the natural processes that regulate the hydrological cycle, especially for spatial and temporal analyses of these processes. This work aimed to explore spatial and temporal trends of reference evapotranspiration (ETo), evaluate ETo variation dynamics and quantify the contribution of each one of the meteorological variables in ETo calculation in the São Francisco River basin. Daily data of maximum and minimum air temperature, mean relative air humidity, wind speed and net radiation from 101 weather stations, for the period from 1961 to 2015, were used and are part of the network of the National Institute of Meteorology (INMET). Climate trend analysis was performed using the non-parametric Mann-Kendall statistical test and the sensitivity analysis for the Penman-Monteith equation was carried out based on partial derivatives as a function of the key meteorological variables of ETo (air temperature, net radiation, wind speed and actual water vapor pressure). A significant increase (p<0.01) in vapor pressure deficit (VPD) associated with the increase in mean air temperature contributed to increments in ETo along the studied period. The scenario in the entire São Francisco River basin is of increase in the values of the climatic variables, particularly evapotranspiration (85% of basin area with increments) and rainfall (52% of basin area with decrements). Results indicate an increase in ETo variation rates of approximately 2.424 mm year-2, on average, in the entire basin. The energy term represents higher weight in ETo calculation in 81% of the basin territory.
Correlating MRI-Based Brain Volumetry and Cognitive Assessment in Down Syndrome Patients
Authors: Hamadelseed Osama , Skutella Thomas
Published: January 2022

INTRODUCTIONDown syndrome (DS) is the most common genetic cause of intellectual disability. Children and adults with DS show deficits in various aspects of language performance and explicit memory. Here we use magnetic resonance imaging (MRI) on children and adults with DS to characterize changes in the volume of specific brain structures involved in memory and language and their relationship to features of cognitive-behavioral phenotypes.METHODSThirteen children and adults with the DS phenotype and 12 age- and gender-matched healthy controls were analyzed by MRI and underwent a psychological evaluation for language and cognitive abilities.RESULTSThe neuropsychological profile of DS patients showed deficits in different cognition and language domains in correlation with reduced volumes of specific regional and subregional brain structures. Intriguingly, our DS patients showed also a reduced parahippocampal gyrus volume, in contrast with the results found by other researchers.CONCLUSIONSThe memory functions and language skills affected in our DS patients correlate significantly with the reduced volume of specific brain regions, allowing us to understand DS's cognitive-behavioral phenotype. Our results provide an essential basis for early intervention and the design of rehabilitation management protocols.
Efficacy and Safety of Adrenergic Alpha-1 Receptor Antagonists in Older Adults: A Systematic Review and Meta-analysis for the Development of Recommendations to Reduce Potentially Inappropriate Prescribing
Authors: Mansbart Felix , Kienberger Gerda , Sönnichsen Andreas , Mann Eva
Published: January 2022

BackgroundAdrenergic alpha-1 receptor antagonists (alpha-1 antagonists) are frequently used medications in the management of lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and in the management of therapy-resistant arterial hypertension, two conditions frequently found in older adults. This systematic review aims at presenting a complete overview of evidence over the benefits and risks of alpha-1 antagonist treatment in people ≥ 65 years, and at deriving recommendations for a safe application of alpha-1 antagonists in older adults from the evidence found.MethodsA comprehensive literature search was performed including multiple databases (Medline/Pubmed, Embase, the Cochrane Library) and using the PICOS framework to define search terms. The selection of the studies was done by two independent reviewers in a two-step approach, followed by a systematic data extraction. Quality appraisal was performed for each study included using standardised appraisal tools. The studies retrieved and additional literature were used for the development of recommendations, which were rated for strength and quality according to the GRADE methodology. ResultsFourteen studies were included: 3 meta-analyses, 6 randomised controlled trials and 5 observational trials. Doxazosin in the management of arterial hypertension was associated with a higher risk of cardiovascular disease, particularly heart failure, than chlorthalidone. Regarding treatment of LUTS suggestive of BPH, alpha-1 antagonists appeared to be effective in the relief of urinary symptoms and improvement of quality of life. They seemed to be less effective in preventing disease progression. Analyses of the risk profile indicated an increase in vasodilation related adverse events and sexual adverse events for some agents. One large observational study points at an increased risk of falls and fractures. The effects of long-term treatment remained unclear. All meta-analyses and 5 out of 6 interventional studies were downgraded in the quality appraisal. 4 out of 5 observational studies were of good quality.ConclusionsIt cannot be recommended to use doxazosin as first-line antihypertensive agent neither in older adults nor in younger patients. In the management of BPH alpha-1 antagonists promise to effectively relieve urinary symptoms with uncertainty regarding their efficacy in preventing long-term progression events.
Changes in Effective Optical Zone After Small-Incision Lenticule Extraction in High Myopia
Authors: Sun Lixia , Lin Hui-Ni , Jhanji Vishal , Ng Tsz Kin , Ji Rui-feng , zhang riping
Published: January 2022

Purpose: To evaluate the four measurement approaches on the determination of effective optical zone (EOZ) using Scheimpflug tomography after SMILE surgery in eyes with high myopia.Setting: Corneal refractive surgery conducted in eye hospital in southern ChinaDesign: A retrospective cohort study.Methods: Total 74 subjects were recruited. EOZ was measured at 3 months postoperatively using Vertex-Based total corneal refraction method (EOZV), pupil-based total corneal refraction method (EOZP), 4 mm-Ring-Based total corneal refraction method (EOZ4), and axial curvature difference map (EOZD), and their consistencies were compared. EOZs and planned optical zone (POZ) were compared and analyzed with eccentricity, ablation degree (AD) and total corneal aberrations.Results: Mean AD was -6.87 ± 0.75 D, and eccentricity was 0.30 ± 0.17 mm. At 3 months after surgery, the mean root mean square of ΔHOA, ΔComa, ΔTrefoil and ΔSA were 0.53 ± 0.27 μm, 0.36 ± 0.20 μm, 0.01 ± 0.84 μm, and, 0.16 ± 0.14 μm respectively. EOZV, EOZP, EOZ4 and EOZD were 5.87 ± 0.44 mm, 5.85 ± 0.45 mm, 4.78 ± 0.40 mm, 5.29 ± 0.27 mm respectively, which were significantly smaller than POZ 6.48 ± 0.16 mm. Bland Altman plots showed a good consistency between the four EOZs. The difference between the EOZV and EOZP was 0.02 mm within the range of clinically acceptable difference. In addition, EOZD was positively correlated with AD, and the eccentricity was positively correlated with ΔHOA, ΔComa and ΔSA.Conclusions: All 4 measurement approaches demonstrated the reduction of EOZs compared to POZ. EOZV was the closest to POZ, followed by EOZP. ΔEOZs showed no significant difference with eccentricity, AD and corneal aberrations. Our results are useful for the full characterization of corneal treatment profiles after kerato-refractive surgery.