bluuebunny/crossref_metadata_2025 huggingface dataset:
Phenotypic Characters and TYRP1 Polymorphism of F4 Golden Kamper Hybrid Chickens (Gallus gallus domesticus Linnaeus, 1758)
Authors: Firmansyah Gilang Ilham , Perdamaian Ayudha Bahana Ilham , Daryono Budi Setiadi
Published: July 2022

Golden Kamper is a local meat-typed chicken with four generations of Pelung male and Layer female selective breeding. This chicken has various plumage colors and patterns. Therefore, the desired plumage color is red barred plumage (B1). In chickens, the missense mutation in the Tyrosinase-related-proteins 1 (TYRP1) causes a chocolate color plumage (choc) with an epistatic effect on barred plumage. The current study aimed to observe the growth of 16 chickens from hatching until 49 days of age to investigate the phenotypic characteristics, especially plumage color at 49-day-old chickens, then to determine the effect of the TYRP1 polymorphism on F4 Golden Kamper phenotypes. The methods used in this study included selective breeding among F3 Golden Kamper, collection of F3 Golden Kamper's eggs, then rearing the day-old chickens of F4 Golden Kamper. Phenotypic data were collected and blood collection was performed for DNA isolation, DNA amplification, and sequencing. Of 16 F4 Golden Kamper, all chickens had a uniform comb type of single (rprp, 100%). The produced shank colors were white (31.25%), yellow (62.5%), and blackish gray (6.25%). The plumage colors were red barred (12.5%), white barred (12.5%), brown (68.75%), and chocolate (6.25%). The bodyweight of F4 Golden Kamper at the age of 7 weeks reached 597.3 g. The morphometric results indicated that F4 Golden Kamper had the same posture and body proportions as Pelung chickens, however, with a higher weight. Fourteen substitutions were found in the TYRP1 fragment of F4 Golden Kamper. The single nucleotide polymorphisms (SNP) had no correlation with the chocolate plumage phenotype in F4 Golden Kamper. The evaluated SNPs in TYRP1 were not associated with the brown plumage color phenotype.
VIOLENCIA HACIA LOS ADULTOS MAYORES DURANTE EL CONFINAMIENTO POR COVID-19
Authors: Estrada Álvarez Carlos Mario , Hernández Hernández María Antonia , Castellanos Suárez Viviana
Published: July 2022

El siguiente estudio pretende señalar el aumento de la violencia hacia los adultos mayores durante el confinamiento derivado de la pandemia por COVID-19, para ello se realizó un análisis a partir de la revisión de artículos indexados y fuentes oficiales nacionales e internacionales; por medio del uso de palabras clave, se analizan los factores y escenarios de violencia en los niveles: macro social, grupal e individual y se distinguen también las afectaciones para el adulto mayor, así mismo se analizó la violencia estructural que funciona en contra de los grupos más vulnerables. Se logra identificar la presencia de la violencia a partir del confinamiento involuntario, ya que se omitieron factores de cuidado, atención y vulnerabilidades físicas y psicológicas ante la condición de aislamiento, lo cual atenta a su bienestar y se fomentan prácticas violentas que pasan desapercibidas por los órganos correspondientes de guardar la salud e integridad del adulto mayor. Las decisiones tomadas durante el confinamiento por medio de las medidas preventivas, determinó la retención y privación del movimiento del sector adulto, lo que ocasionó una omisión a los derechos de los adultos mayores, convirtiéndolos en rehenes de sus propios agresores, hogares y de la sociedad.
ОСОБЕННОСТИ ДЛИТЕЛЬНОСТИ ЗУБЦОВ И ИНТЕРВАЛОВ ЭКГ В СТАНДАРТНЫХ И ГРУДНЫХ ОТВЕДЕНИЯХ У МУЖЧИН И ЖЕНЩИН ЗРЕЛОГО ВОЗРАСТА
Authors: Абумуслимов С.С. , Ахмадова З.М. , Мачиева Ж.А.
Published: July 2022

В работе были исследованы гендерные различия электрокардиографических параметров у женщин и мужчин зрелого возраста с помощью усовершенствованного электрокардиографа Альтон-06. Были исследованы три стандартных и шесть грудных отведений у испытуемых. Анализировалась длительность зубцов, интервалов и сегментов электрокардиограммы. Было установлено, что некоторые исследованные графоэлементы ЭКГ имеют половые различия в стандартных отведениях. Причем в разных стандартных отведениях у мужчин и женщин отличались разные графоэлементы. Что касается грудных отведений, то длительность зубцов ЭКГ не имела статистически значимых отведений ни в одном из них. Таким образом, исследование ЭКГ сердца в различных отведениях характеризуют биоэлектрическую активность различных участков сердца и позволяет более шире проводить анализ половых различий.
АДМИНИСТРИРОВАНИЕ МАРКЕТИНГОВОЙ ДЕЯТЕЛЬНОСТИ ПРОИЗВОДИТЕЛЕЙ
ОРГАНИЧЕСКОЙ ПРОДУКЦИИ
Authors: Бекмурзаев И.Д. , Дадаев Я.Э.
Published: July 2022

В статье рассмотрены составляющие процесса администрирования предприятия, содержащие как материальные, так и нематериальные активы и обеспечивающие эффективность хозяйствования. Предложена последовательность этапов совершенствования администрирования маркетинговой деятельности, что дает возможность, исходя из технико-экономического анализа показателей хозяйственной деятельности, сформировать направления совершенствования администрирования маркетинговой деятельности производителей органической продукции для реализации стратегии эко-инновационного развития производства органической продукции. Также проведена систематизация основных функций (плановая, организационная, управленческая, исполнительская и контрольная), принципов и задач реализации разработанных направлений совершенствования администрирования маркетинговой деятельности производителей органической продукции.
СТРАТЕГИЯ УПРАВЛЕНИЯ КЛИЕНТСКИМ ОПЫТОМ
Authors: Бекмурзаев И.Д. , Саидов А.А.
Published: July 2022

Статья посвящена исследованию процесса управления клиентским опытом как стратегии развития бизнеса и гене-рации дополнительного дохода от роста бренд-капитала компании. На фоне роста потребительских ожиданий и усиления конкуренции качество управления клиентским опытом становится факто-ром выживания современных компаний. Разработка стратегии управления клиентским опытом направлена на повышение эффективности цепочки создания ценности клиентского опыта. В структуре процесса управления клиентским опытом выделены аналитические, организационные, управленческие и контроль-но-оценочные мероприятия. Предложена общая схема разработки стратегии управления клиентским опытом, состоящая из последовательных этапов: формирование сервиса; структурирование точек контакта; разработка плана действий; определение бюджета и ресурсов; распределение ролей и сфер ответственности; создание нового опыта клиентов и оценка результатов имплементации.
БИЗНЕС-ПЛАНИРОВАНИЕ И ЕГО РОЛЬ В УПРАВЛЕНИИ БИЗНЕСОМ
Authors: Газиева Л.Р.
Published: July 2022

Актуальность данного исследования обусловлена необходимостью изучения бизнес-планирования как одного из предпосылок успешного функционирования предприятия и разработки бизнес-плана для открытия нового предприятия. Не-смотря на многие трудности, в сфере предпринимательства во всём мире заняты миллионы людей. Бизнес – это совершенно особая манера существования. Она предполагает принятие решений и риск. Предприниматель, решающий заняться бизнесом, должен чётко спланировать его организацию. Любое коммерческое предприятие принято начинать с составления бизнес-плана. В условиях рынка такие планы необходимы абсолютно всем. Бизнес-планирование является необходимым условием для существования и развития в современных рыночных условиях. И преуспевает та фирма, которая смогла максимально учесть возможные факторы внешней и внутренней среды. При разработке бизнес-плана нужно оценивать все возможности предприятия и внешней среды, разрабатывать четкие и достижимые цели и располагать ресурсами для их достижения.
РЕГУЛИРОВАНИЕ ДЕЯТЕЛЬНОСТИ ГОСУДАРСТВЕННЫХ УНИТАРНЫХ ПРЕДПРИЯТИЙ
Authors: Газиева Л.Р. , Ильясова К.Х.
Published: July 2022

Развитие экономики практически невозможно без стабильной работы предприятий унитарного типа. Данная форма организации субъектов хозяйствования четко регламентирована действующим законодательством РФ. Реформирование реального сектора экономики требует серьезных денежных вложений. От-дельного внимания заслуживает идея формирования единой системы критериев. Функционирование системы государственной собственности может претерпевать изменения на фоне транс-формационных процессов общества. Автором в статье раскрываются сущностные черты государственных унитарных предприятий и выработка предложений по совершенствованию механизмов управления их организации и деятельности. Рассмотрена прибыль и рентабельность в условиях предпринимательства, также приведена оценка влияния внешней и внутренней среды хозяйственной деятельности государственных и муниципальных унитарных предприятий. Выявлена роль и задачи анализа финансовых результатов деятельности организации.
СТИЛИ РУКОВОДСТВА: ВОВЛЕЧЕННОСТЬ СОТРУДНИКОВ В РАБОТУ В НЕКОММЕРЧЕСКИХ ОРГАНИЗАЦИЯХ
Authors: Довлетмурзаева М.А. , Юшаева Р.С.-Э. , Дикаева Х.М.
Published: July 2022

В данной статье рассматривается поведение лидеров и то, как их деятельность влияет на поведение членов организации. Также рассматривается роль вовлеченности сотрудников в работу как промежуточный механизм эффективной деятельности организации. Лидерство всегда влияло на эффективную приверженность и организационное поведение, а вовлеченность в работу оказывало значительное и положительное влияние на взаимосвязь между переменными. Из-за ограниченного количества исследований по теме лидерства в некоммерческих организациях любое исследование является ценной информацией, теоретически и эмпирически вносит свой вклад в литературу по лидерству, поскольку авторы исследуют два стиля лидерства в отношении результатов, связанных с работой, через вовлеченность в работу в не-коммерческом секторе.
Islamic Perception of Anxiety: A Conceptual and Comparative Analysis with Psychology
Authors: Mehmood Dr. Muhammad Tariq , Kausar Dr. Samina
Published: July 2022

Anxiety is the most prevailing issue from the last decades. Many factors including emotional, genetics, personality, cognition and environmental lead towards anxiety and depression. With the rapid increase in stress and tension, there exist a corresponding need to highlight and discuss the coping and adaptive strategies of Islam to deal with the issue.  The study sought to investigate the most common phenomena of the day, anxiety and its treatment and solutions in the perspective of Islam. In this study multiple strategies, therapies and methodologies are discussed which offered by Islam to overcome the problem. A person who suffer from anxiety, remains in stress, fear, anger, have negative thoughts and sometime severely attack to kill someone. Anxiety have impact on physical, mental, psychological, emotional and social aspects of life of anxious person.   Symptom of anxiety depends upon the type and severity of disorders. In Diagnostic and Statistical Manual   Disorders (DSM-IV) six types of anxiety disorders are identified and discussed.
Negotiating Modernity with Caution: Women of Jama’at-e- Islami Pakistan
Authors: Ahmad Dr. Humaira , Dr Mian Muhammad Rafi
Published: July 2022

Role of Muslim women in public sphere has been a highly contested topic among international academia since many decades. Dominant Orientalist approach assumes universal and monolithic Islam that is uncompromisingly oppressive to women and confines them in homes. Many of recent studies contest this view and term it as reductionists. This article focusses on the transformation of policies of Jama’at-e-Islami Pakistan (JI), as a representative of contemporary Islamic movements, on the issue of Muslim women’s participation in public sphere and adoption of modernity at their own terms. It investigates the underpinning of these trajectories traversed by the party, synthesising the modernity with Islamic Principles. Research is qualitative in nature and based on textural analysis of the documents i.e. published material (books, articles, proceedings, resolutions, interviews etc.). Input managed through few face-to-face semi structured interviews is also included. Study shows gradual change in party policy; from hesitation in granting even rights of vote to the women, to putting women candidates for assemblies, involving them in street protests and using all modern techniques to further party’s agenda but at their own terms. Study finds that JI has taken every step for opening of public sphere for women, using all the available opportunities, resources and platforms. However there is conspicuous consistency in their narrative that, the first and most important responsibility of women is her home and family. When policies of JI on the issue are viewed in western feminism framework, these seem quite restrictive, oppressive and detrimental to women rights, however, there are others who admit that slowly and steadily, JI women, by using selective tools of modernity, have taken over the major portion of public space, once solely dominated by the secular women organizations in Pakistan.
PENGUATAN KARAKTER (PROFIL) PELAJAR PANCASILA MELALUI KEGIATAN PESANTREN RAMADHAN (STUDI DI SD ISLAM PLUS SALSABILA AL IKHSAN MAGELANG)
Authors: Hozaimi Hozaimi
Published: July 2022

Penelitian ini bertujuan untuk mendeskripsikan penguatan karakter (profil) pelajar Pancasila melalui kegiatan Pesantren Ramadhan. Penelitian dilakukan di SD Islam Plus Salsabila Al Ikhsan Magelang pada Bulan Ramadhan hingga Syawal tahun 1443 Hijriyah, bertepatan dengan Bulan April hingga Mei tahun 2022 Masehi. Metode yang digunakan dalam penelitian ini adalah observasi, kajian dokumentasi, dan wawancara. Hasil analisis menunjukkan bahwa karakter (profil) pelajar Pancasila yang terdiri atas (1) beriman, bertakwa kepada Tuhan Yang Maha Esa, dan berakhlak mulia, (2) berkebhinnekaan global, (3) bergotong royong, (4) mandiri, (5) bernalar kritis, dan (6) kreatif, ditemukan pada rangkaian acara pada Pesantren Ramadhan di SD Islam Plus Salsabila Al Ikhsan Magelang terdiri atas (1) Safari Bhakti Masjid, (2) Belajar Membaca dan Menghafal Qur’an, (3) Tematik asyik, (4) Berbagi Berkah, (5) Malam Bina Iman dan Takwa (MABIT), (6) Latihan Adzan, (7) Latihan Pidato/Ceramah, (8) Kreativitas (Life Skill), dan (9) Halal bi Halal. Hal ini menunjukkan bahwa penguatan karakter (profil) pelajar Pancasila dapat dilakukan melalui kegiatan Pesantren Ramadhan.
Trinidad Cruz: Artesano centenario de aldea Azulco
Authors: Esquivel Vásquez Aracely
Published: July 2022

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The legal regulation of the common-law marriage with the contract of partnership in German Law
Authors: Chechulin Mykola
Published: July 2022

The article reveals the features of legal regulations of common-law marriage in German law by the so called «contract of partnership». Unfortunately, in civil law of Germany the common-law marriage is party admitted, that’s why the con-tract of partnership allows persons to regulate their relations without marriage und ensure the protection of basic rights in family law. The article provides the main definition, laws of contract of partnership, the mutual rights and obligato-ry, that citizens could include in this kind of contract. At the end, author makes conclusions about efficiencies of contract of partnership and possibilities for re-search and reception into Ukrainian and international private law to regulate common-law marriage.
Effects of Moxibustion at CV8 on Prohibitin-1 Expression and Mitochondrial Function in Skeletal Muscles of Rats With Long-Term Exercise-Induced fatigue
Authors: Liang Yulei , Lv Shiling , Xu Xiaokang , Li Ruida , Wang Xin , Zhu Jie , Li Si , Li Wenli , Sun Dongyun , ChaoyiFang
Published: July 2022

Background: Physiological exercise-induced fatigue is a potential risk factor to human body in motion which can restrict the effectiveness of training and resulting muscle and joint strain. Both ancient texts and modern clinical reports have shown that moxibustion at CV8 alleviates
exercise-induced fatigue. However, the pathophysiological mechanism of action is still unclear. Objective: To investigate the effect of moxibustion on mitochondrial energy metabolism in skeletal muscle of fatigued rats. Materials and Methods: In this study, rats treated with
moxibustion for 8 weeks to assess its efficacy in enhancing energy metabolism in skeletal muscle. Succinate dehydrogenase (SDH), malate dehydrogenase (MDH), adenosine triphosphate (ATP), prohibitin-1 (PHB1), FoF1-ATPase and mitochondrial morphology of the biceps femoris were analyzed to explore
evidence of moxibustion in long-term exercise. Results: Our research indicated that moxibustion could reduce the levels of biceps MDH, PHB1 and FoF1-ATPase in fatigued rats, and increased SDH and ATP levels. The electron microscopy showed that the mitochondrial morphology in the untreated
and non-acupoint groups swollen, the cristae either decreased or fractured, but the degree of CV8 group was significantly lower than the other two groups. Conclusions: Moxibustion at CV8 relieves motor fatigue by regulating the energy metabolism of skeletal muscle and is a safe and
effective non-drug treatment.
Poland in International Relations in Europe: British Government Circles Assessments on the Еve of the Locarno Conference of 1925
Authors: Dubrouka Alena
Published: July 2022

The article is devoted to the identification and analysis of assessments by representatives of British government circles of Poland place and role in international relations in Europe on the eve of the Locarno Conference.
The sources for the work were the documents of the Foreign Office, the Cabinet, and the parliamentary debates materials for the period from November 1924 to October 1925.
The emergence of Cabinet members and parliamentarians assessments of Poland's place and role in international relations was facilitated by the solution of current foreign policy tasks in Europe: discussion of the Geneva Protocol, adopted on October 2, 1924 at the Assembly of the League of Nations, signing.  Аfter the UK's rejection of it, guarantee pact drafts discussion, which ended with the signing of agreements in Locarno. The assessments made at the time were directly or indirectly related to such aspects of international relations as Polish-German, Polish-French relations, Poland's relations with the Baltic countries, primarily Lithuania, and policy towards Soviet Russia.
It is shown that the dominant influence on the assessment of Poland's place and role in European relations by the British government circles at that time was exerted by current economic interests, ideas about national security tasks and the tradition of focusing in European politics exclusively on the "great powers", which led to some disregard for the interests of Poland.
An Attempt for a Compromise Solution of the Shakespeare Question
Authors: Hakobyan Ruben
Published: July 2022

The proposed article is an attempt to look at the problem of the authorship of the works of William Shakespeare (Shakespeare authorship question), as if from the outside, since the author, considering this problem to be real, is not, however, a staunch supporter of any one approach.
Shakespeare's question is two hundred years old. This is generally thought to be a problem with the authorship of Shakespeare's works. But in fact, the question lies in the very reason for the emergence of doubts about the authorship — in the discrepancy between the image of the real person — Will Shakespeare from Stratford, the image of the playwright and poet William Shakespeare, which is formed in the reader under the influence of his works. And with this approach, the Shakespearean question can be resolved not only by proving one or another alternative authorship, but also if, within the framework of traditional authorship, the reasons for this discrepancy are explained, or if it is shown that the discrepancy is apparent.
However, instead, supporters of traditional and alternative authorship further increase this gap between the two images: on the one hand, an opinion is created and maintained about the unprecedented erudition of the playwright Shakespeare, and on the other, about the lack of education of the real Shakespeare.
Moreover, representatives of both approaches show dishonesty in their research, and at the same time they reproach the other side for the unscientific approaches.
The article points out that any solution can be convincing only if it explains the nature of the contradictions between the personality of the real Shakespeare and the world of Shakespeare's works.
And for this it is necessary to answer the main question: at what moment and how Shakespeare from Stratford became close to high society.
The author comes to the conclusion that the known facts can be explained and reconciled only by the assumption that the connecting link could be one of the "candidates" for the role of the author of Shakespeare's works, the Earl of Rutland, and that Will was recommended to the Earl's family by a very influential person. Moreover, it seems that there is only one candidate for the role of such a person — his mother — Mary Arden.
 
The stated hypothesis makes it possible to explain the main oddities associated with the personality and work of William Shakespeare, who thus combined two worlds — each with its own system of values.
Globalization and the Industrial Sector Performance: The Nigeria Experience
Authors: Nwokoye Ebele Stella , Chukwuka Stephen M. , Emmanuel Akpoghelie Oghenekome , Ikemefuna Ebuwa Emmanuel
Published: July 2022

Globalization is said to be a hallmark for modern economic growth and development. Since 1970, the volume of world trade has grown by around 7% yearly. The Nigerian industrial sector after experiencing boom in the first two decades after Nigeria’s independence, has suffered from low productivity afterwards. Therefore, this study examined the impact of globalization on Nigeria industrial sector performance from 1986 - 2017. The study utilized secondary data from the Central Bank Statistical Bulletin (CBN), and National Bureau of Statistics (NBS). The data were analyzed using Ordinary Least Squares (OLS), Error Correction Model, ADF Unit root test, Johansen Co-integration test, Cholesky variance decomposition test. The findings of this study show that “free-trade” which came as a result of globalization has a not impacted Nigeria industrial output enough to trigger economic growth and also, that Nigeria depends so much on imported products which have made the industrial sector weak and unable to compete with her foreign counterparts. The study also revealed that globalization has led to the stagnation of Nigeria’s Manufacturing index. This implies that the cost of globalization for Nigeria have outweighed its benefits, hence; the study concluded that globalization has done more harm than good to Nigerian economy. The study recommends that Nigeria should put in place an industrial policy which should create enabling business environment within the country by providing incentives to manufacturers, ensuring regular and uninterrupted power supply as well as promoting agriculture.
Important Comparison About the Use of Multiple Linear Regression and Logistic Regression with Applications
Authors: AbuElgasim Abbas Abow Mohammed
Published: July 2022

This is paper presented a multiple linear regression model and logistic regression model, according to assumptions of both models. The paper depended on logistic regression model because the dependent variable is nominal. It also used preparatory year data collected from the College of Business and Economics, Qassim University to know the effect of student grades and gender, as independent variables, on the student status as dependent variable. The paper found that the grades have not a significant effect on the student status while the gender has a significant effect on the student status. The comparison between the multiple regression model and the logistic regression model showed that the logistic regression model is the most appropriate for determining the relationship between the student's status as a dependent variable and the students' grades, and gender as independent variables. The paper recommends the use of logistic regression, especially if the dependent variable is nominal.
Sludge Removal at Krško NPP Steam Generators during Outage
Authors: Kelavić Robert , Turalija Marko
Published: July 2022

Sludge removal is performed on two steam generators (SG’s) at the Krško Nuclear Power Plant (NEK) during every outage. SG’s are a meeting point of four major plant systems: Reactor Coolant System (RC) on the primary side and three systems on the secondary side – Auxiliary Feedwater System (AF), Main Feedwater System (FW) and Main Steam System (MS). Sludge removal activities take place on the secondary side of the SG’s on the top of the tube sheet. It consists of classical Sludge Lancing (SL) which is done by spraying water at different angles (30°, 90°, 150°) between the tube gaps in the steam generator tube bundle with a pressure around 220 bars. Another method is Inner Bundle Lancing (IBL) which means spraying water at a much higher pressure (NEK’s contractor reached a pressure of approximately 590 bars). Such water is sprayed directly on the top of the tube sheet with a robot guided lance which is placed inside a steam generator. The robot is controlled by an operator and at times fully autonomous to provide the highest protection measures possible. After these activities, a televisual inspection (TVI) of the top of the tube sheet is performed to access the hard sludge area and to search for potential foreign objects in the SG’s. If an object is found, an attempt to retrieve it would usually take place. Other methods of sludge removal as upper bundle flushing or chemical cleaning have not been implemented in NEK thus far. Since the power plant uprate in May 2000, NEK conducted SL on both SG’s every outage with IBL in 2013 and 2015 and the same method was used in the 2018 outage. The purpose of these activities is mainly to extend the full load operation of the plant, prevent denting processes in the SG’s from occurring, stop the buildup of hard sludge area to increase/sustain efficiency and remove foreign objects found in the SG’s. SG’s U-tubes are a barrier between the primary side coolant and the secondary side of NEK and the environment. Therefore, it is crucial to keep the highest level of integrity of the U-tubes because any leak could potentially mean a release of radioactive material to the atmosphere. This paper describes the purpose and workflow of sludge removal in NEK.
Assessment of the Photon and Neutron Source Term for the NPP Krško Spent Fuel
Authors: Kromar Marjan , Kurinčič Bojan
Published: July 2022

Accurate knowledge of the fuel nuclide inventory is important after reactor shut down, during the fuel storage and subsequent reprocessing or disposal to provide adequate shielding from the photon and neutron radiation. In this paper possibility to calculate the NPP Krško photon and neutron source term with the Serpent code has been analysed. Some deficiencies in the supplied ENDF/B-VII.0 decay library have been observed. In addition, Serpent reports only spontaneous fission rates without (α, n) and (β, n) contributions. To get neutron emission, spontaneous fission rates had to be multiplied with the average number of neutrons born for each particular nuclide manually. Comparison with the Origen code has shown acceptable agreement of the ENDF/B-VII.1 results. Influence of several factors such as fuel burnup, enrichment, temperature, moderator temperature (density), soluble boron concentration, average power, and burnable absorbers has been analysed. In addition, it was demonstrated that, except for the burnup and enrichment, averaging of all other parameters is acceptable approach. IFBA fuel should be accounted for explicitly due to relative high impact on the photon and neutron emissions.
Development and Validation of Novel FTIR Method for Quantitative Estimation of Silodosin in Bulk and Pharmaceutical Dosage Forms
Authors:   Department of Pharmaceutical Analysis, G. Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad, Telangana 500028, Guru Sai Supriya B , Raghavendra Babu N ,   Department of Pharmaceutical Analysis, G. Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad, Telangana 500028, Padmavathi Y ,   Department of Pharmaceutical Analysis, G. Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad, Telangana 500028, B Sai Chaitanya Reddy ,   Gitam School of Pharmacy, Gitam deemed to be university, Hyderabad, Telangana 500028, Sai Pavani G ,   Gitam School of Pharmacy, Gitam deemed to be university, Hyderabad, Telangana 500028
Published: July 2022

Silodosin was quantified in both pure and pharmaceutical dosage forms using a novel Fourier transform infrared (FTIR) spectroscopic technique. Silodosin is an alphablocker that works by relaxing the bladder and prostate muscles to alleviate benign prostatic hyperplasia symptoms. After baseline correction, the infrared spectrum revealed a variety of peaks, including intense, distinct peaks at 1620 cm-1 (C=O), 3201.61 cm-1 (NH), and 3384.84 cm-1 (OH). The method met the majority of validation requirements in the 40–200 g/mg range, with a coefficient of determination of 0.998, obtained using a simple calibration model. While FTIR methods are less complex, less expensive, and faster than other methods, they can be used to estimate silodosin in a variety of dose forms. Key words: FTIR, Infrared spectrum, baseline correction, validation.
ANALYZING THE IMPACT OF SLEEP TRAIT IN THE DETECTION AND PREDICTION OF STRESS THROUGH MACHINE LEARNING
Authors:   Assistant Professor, Department of Artificial Intelligence and Machine Learning, Coimbatore Institute of Technology., Priyadharshini Jayadurga N , Aruna P ,   Assistant Professor, Department of Software Systems, Coimbatore Institute of Technology.
Published: July 2022

People are thriving towards perfection, performance, and profit in the society which inturn is leading to disturbances among them both mentally and physically. One issue faced by most of the people irrespective of the age groups is “Stress”. With the onset of Covid-19 pandemic, Stress has become a disastrous disorder faced by most of the people today. Most of the people are unaware that they are suffering from such a disorder. Stress lays in the hands of at-most all people either knowingly or unknowingly. There are numerous methods to detect stress manually. People don’t come forward to take up treatments for stress. This disorder peeps out of humans through various symptoms like irritation, loss of appetite, agitation, depression, anxiety, reduced performance, sleep disturbance, etc. Among the afore mentioned symptoms, sleep disturbance is the major and most influential parameter in detecting and predicting stress. The SaYo Pillow is the “Smart-Yoga Pillow” which assists in concerning the relationship pertaining to sleep and stress. Although there are other methods to track sleep like Fitbit trackers to track sleeping patterns, SaYo Pillow stands out as it detects the psychological behaviors that occurs during sleep. This tracking of psychological behavior is lacking in case of other devices like Fitbit used for sleep pattern detection. The data obtained from this pillow can be used to study how stress can affect sleep. Machine Learning methods are applied to the data to detect if the person is stressed or not. Thereby adding to it, prediction is also done to understand will the person be stressed in near future. Machine Learning algorithms such as Support Vector Machine (SVM), Random Forest Classifier and Gradient Boosting Classifier was used to detect and predict stress among the individuals. The performance of these algorithms was compared to identify the best performing algorithms. After identifying the best performing algorithm, the same was applied to the data to detect and predict the occurrence of stress. In addition to that, an application was developed which suggests some activities to the candidate to overcome stress.
ℝ𝑶𝑼𝑮𝑯 𝓸𝑯(𝟏,𝟐)∗ GENERALIZED PRE-HOMEOMORPHISMIN ROUGH BITOPOLOGICAL SPACE
Authors:   Research Scholar, Department of Mathematics, Mother Teresa Women’s University Research and Extension Centre , Coimbatore, SHAKILAJA K , BHUVANESWARI K ,   Associate Professor and Head, Department of Mathematics, Mother Teresa Women’s University Research and Extension Centre , Coimbatore.
Published: July 2022

The aim of this paper is to introduced and study a new class of functions called ℝ𝑜𝑢𝑔ℎℴ𝐻(1,2)∗ generalized pre-homeomorphism function (briefly ℝℴ𝐻(1,2)∗𝑔𝑝ℎ𝑓 ) in Bitopological Space and to analysis some properties and its relation with existing functions are studied. Keywords: ℝ ℴ𝐻(1,2)∗𝑔𝑝ℎ𝑓 , ℝℴ𝐻(1,2)∗gp – C, ℝℴ𝐻(1,2)∗ 𝑔𝑝 – closed set, ℝℴ𝐻 (1,2)∗- open set
A Case Study Analysis of VMS and Its Implementations in Small Scale Fisheries
Authors:   MSc Industrial Fisheries, School of Industrial Fisheries,  Cochin University of Science and Technology, Kochi, 682016, Raghu Susmera B , V P Ancy ,   Assistant Professor, School of Industrial Fisheries, Cochin University of Science and Technology, Kochi, Kerala, India
Published: July 2022

The fisheries sector is really difficult to produce the catch quantities of small-scale fisheries because of lack of proper monitoring. Vessel Monitoring System (VMS) is an important tool that allows the government to monitor small-scale fishing vessel activities. Implementation of VMS in small-scale fisheries is a powerful solution for unauthorized data. VMS provide economic benefits as most of fishermen are nowadays equipped with smartphones. With the recent technological advancements, the VMS has improved and it allows integrated fisheries management. The present study focused on the role of VMS in small-scale fisheries and how the government is helping small-scale fishermen to implement such technologies through subsidies. The knowledge of small-scale fishermen about the technological advances in fisheries and the role of government in helping them to implement such technologies was analyzed through a questionnaire. This study seeks to explore the challenges faced by fishermen for implementing such technologies, whether they are aware of the government schemes and subsidies and their overall opinion about government services. It is observed that access to new technologies by small-scale fishermen is limited by their financial difficulties. The operating and maintenance cost of the VMS system depends on the functionality requirements of the specific system. The higher the functionality, the more expensive will be the system. Policies and programmes are developed by Fisheries Department and implemented through proper organizations to ensure the access of small-scale fishermen to new technologies. The future of fisheries management will depend on a whole ecosystem of new technologies. Keywords: VMS in small-scale fisheries, IUU fishing, fisheries management, small-scale fishermen, government schemes and policies
Tricho-rhino-phalangeal syndrome associated with congenital cytomegalovirus infection
Authors:   II Pediatric Clinic, “Gr. T. Popa” Medicine and Pharmacy University, Iasi, Romania, Ioniuc Ileana , Gotia Stela ,   II Pediatric Clinic, “Gr. T. Popa” Medicine and Pharmacy University, Iasi, Romania, Rugina Aurica ,   II Pediatric Clinic, “Gr. T. Popa” Medicine and Pharmacy University, Iasi, Romania, Colta Mihai ,   II Pediatric Clinic, “Gr. T. Popa” Medicine and Pharmacy University, Iasi, Romania, Murgu Alina ,   II Pediatric Clinic, “Gr. T. Popa” Medicine and Pharmacy University, Iasi, Romania, Alexoae Monica ,   II Pediatric Clinic, “Gr. T. Popa” Medicine and Pharmacy University, Iasi, Romania
Published: July 2022

Tricho-rhino-phalangeal syndrome, disease with genetic determinism, is characterized by abnormal hair growth, facial dysmorphism and skeletal impairment. The evolution of the case is variable according to the three types of the disease. This case is particular by the association with cytomegalovirus infection, the delay in neurologic and cognitive development of the child being affected by both diseases.
Glioamele căilor optice în neurofibromatoza de tip 1 la copil
Authors:   Universitatea de Medicină şi Farmacie ,,Gr. T. Popa“, Iaşi, România, Filipescu Ramona , Poeata Ion ,   Clinica de Neurochirurgie, Universitatea de Medicină şi Farmacie ,,Gr. T. Popa“, Iaşi, România, Grigore Ioana ,   Clinica III Pediatrie, Universitatea de Medicină şi Farmacie ,,Gr. T. Popa“, Iaşi, România, Diaconu Georgeta ,   Clinica III Pediatrie, Universitatea de Medicină şi Farmacie ,,Gr. T. Popa“, Iaşi, România
Published: July 2022

Gliomul de căi optice are expresie clinică maximă în copilărie, în jurul vârstei de 5 ani, fiind a doua tumoră ca frecvenţă în neurofibromatoza tip 1. Topografic se descriu 3 tipuri de glioame de căi optice: tipul I – glioame retrobulbare prechiasmatice, tipul II – glioame de tract optic şi tipul III – glioame chiasmatice. Examenele neuroimagistice sunt esenţiale în stabilirea diagnosticului şi a indicaţiei neurochirurgicale. Managementul acestor tumori este dificil chiar dacă au caracteristici histopatologice benigne. Pacienţii cu glioame de nerv optic simptomatice şi progresie documentată neuroimagistic au indicaţie de rezecţie tumorală. Glioamele de nerv optic asociate neurofibromatozei tip 1 au în general o evoluţie bună, factorii de prognostic nefavorabil fiind reprezentaţi de debutul clinic precoce, sub vârsta de 6 ani şi de afectarea chiasmatică şi retrochiasmatică.
Diagnosticul computer-tomografic în urgenţa pediatrică
Authors:   Unitatea de Primiri Urgenţe, Spitalul Clinic de Urgenţă pentru Copii „M.S. Curie“, Bucureşti, România, Coldea Cristina , Stănescu Diana ,   Departamentul de Radiologie, Spitalul Clinic de Urgenţă pentru Copii „M.S. Curie“, Bucureşti, România, Coman Mariana ,   Departamentul de Radiologie, Spitalul Clinic de Urgenţă pentru Copii „M.S. Curie“, Bucureşti, România, Ferechide Dumitru ,   Catedra de Fiziologie, Facultatea de Medicină şi Farmacie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, România, Bălgrădean Mihaela ,   Catedra de Fiziologie, Facultatea de Medicină şi Farmacie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, România
Published: July 2022

Introducere. Examinarea prin computer-tomograf (CT) deţine un rol important în orientarea diagnostică în Urgenţă. Obiective. Ne-am propus să identificăm utilitatea examinării CT, în urgenţa pediatrică. Material şi metode. Studiul are un design cross-secţional, referindu-se la anul 2010. Din cele 92.959 de vizite înregistrate la Unitatea de Primiri Urgenţe, a Spitalului Clinic de Urgenţă pentru Copii „M.S. Curie“, Bucureşti, un număr de 9.258 pacienţi reprezentau urgenţe (lotul A), iar 90 constituiau urgenţe majore (lotul B). S-au efectuat un număr de 102 examinări CT. Datele au fost exprimate procentual. Rezultate. Procentul de vizite asociat cu examinare CT, a fost de 1% în lotul A şi 1‰, exprimat global. Toţi pacienţii lotului B au fost supuşi investigaţiei CT. Principalele indicaţii au fost: traumatismele cranio-cerebrale (TCC) – 50%, hipertensiune intracraniană (HIC) – 35%, politraumatisme – 12,7% şi suspiciunile de malformaţii – 5,9%. Rata de detecţie globală a unei leziuni a fost de 51%. Pentru TCC, rata a fost de 49%, identificându-se următoarele leziuni: edem cerebral difuz (19%), hemoragii intracraniene (15,6%), fracturi osoase (15,6%), leziuni de părţi moi (29%). Pentru HIC, rata de detecţie a fost de 43%, pentru politraumatisme 84,6%, iar pentru suspiciunile de malformaţii 100%. Ratele de detecţie lezională, pe diverse categorii de indicaţii (senzitivitatea metodei) nu diferă semnificativ statistic faţă de alte studii. Concluzie. La pacienţii de vârstă pediatrică, indicaţiile de CT, în urgenţă, s-au efectuat după o atentă selecţie a cazurilor, iar examinarea s-a dovedit utilă în cazul traumatismelor şi a suspiciunilor de hipertensiune intracraniană.
Evaluarea insulino-rezistenţei la copil: o apreciere critică a modelelor minimale
Authors:   Disciplina de Genetică, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România, Pienar Corina , Stroescu Ramona ,   Clinica I Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Louis Ţurcanu“, Timişoara, România, Chiriţă-Emandi Adela ,   Disciplina de Genetică, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România, Dobrescu Andreea ,   Disciplina de Genetică, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România,   Clinica I Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Louis Ţurcanu“, Timişoara, România, Puiu Maria ,   Disciplina de Genetică, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România,   Clinica III Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Louis Ţurcanu“, Timişoara, România
Published: July 2022

Obezitatea infantilă a urmat, în ultimele două decenii, un trend ascendent. Rezistenţa la insulină (IR) este esenţială pentru fiziopatologia obezităţii. Până în prezent, au fost propuse mai multe metode de evaluare a IR. Ne-am propus evaluarea critică a unora dintre cele mai simple metode folosite pentru determinarea IR la copii şi adolescenţi. Am realizat un studiu retrospectiv al copiilor evaluaţi pentru obezitate în Spitalul Clinic de Urgenţă pentru Copii „Louis Ţurcanu“ Timişoara, pe o perioadă de 10 ani. Populaţia de studiu a fost alcătuită din 342 de copii. Au fost analizate variabilele antropometrice şi metabolice şi au fost evaluaţi următorii indici ai IR: scăderea toleranţei la glucoză (STG), Homeostatic Model of Assessment - IR (HOMA-IR), Homeostatic Model of Assessment- β (HOMA-β), Index cantitativ de verificare a sensibilităţii la insulina (QUICKI), precum şi raportul TG/HDLc. Datele au fost exprimate ca frecvenţă, medie ± deviaţia standard sau media ± intervalul intercuartilic pentru un interval de încredere de 95%. S-a folosit testul t pentru grupuri independente sau testul Mann-Whitney pentru a evalua diferenţele de indici IR, în funcţie de greutate, sex şi dezvoltare pubertară. HOMA-IR a diagnosticat cei mai mulţi copii cu IR, la polul opus am găsit QUICKI. STG a fost rar diagnosticat. Este necesar a se reconsidera modul în care se evaluează metabolismul carbohidraţilor la copii. Dintre posibilităţile existente, HOMA-IR este metoda optimă de evaluare a IR la copii.
Liver disease in children with cystic fibrosis
Authors:   3rd Clinic of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Trandafir Laura Mihaela , Straticiuc Ciongradi Iulia ,   Clinic of Pediatric Surgery, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Baciu Ginel ,   1st Clinic of Pediatrics,“Dunǎrea de Jos” University of Medicine and Pharmacy, Galati, Romania, Anton Paduraru Dana Teodora ,   3rd Clinic of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania
Published: July 2022

Liver disease is an early complication in children with cystic fibrosis (CF).The clinical manifestations in hepatobiliary disease of CF include neonatal cholestasis, liver steatosis, liver fibrosis, biliary lithiasis, focal biliary cirrhosis and multilobular cirrhosis, with or without portal hypertension. Changes in the tests evaluating the liver function are inconsistent and are not correlated with the severity of the liver lesions. The diagnosis of liver disease in CF requires the presence of at least two of the following four diagnosis criteria: clinical manifestations, pathologic liver function tests, ultrasound and histologic changes. The annual follow-up to evaluate the liver function is s recommended for diagnosis of asymptomatic liver disease and early initiation of treatment with ursodeoxycholic acid. The improvement of the liver function influences life quality and increases the survival rate in patients with CF.
Computed tomography imaging in the pediatric emergency department
Authors:   Emergency Department, Clinical Emergency Hospital for Children ”M.S. Curie”, Bucharest, Romania, Coldea Cristina , Stanescu Diana ,   Radiology Department, Clinical Emergency Hospital for Children ”M. S. Curie”, Bucharest, Romania, Coman Mariana ,   Radiology Department, Clinical Emergency Hospital for Children ”M. S. Curie”, Bucharest, Romania, Ferechide Dumitru ,   Department of Physiology, University of Medicine and Pharmacy ”Carol Davila”, Bucharest, Romania, Balgradean Mihaela ,   Pediatric Clinic, Faculty of Medicine and Pharmacy, University of Medicine and Pharmacy ”Carol Davila”, Bucharest, Romania
Published: July 2022

Introduction. The Computerized Tomography (CT) plays a crucial role in the emergency diagnosis. Objective. Our purpose was to identify CT-scan’s utility in Pediatric Emergency Department. Materials and methods. We used a cross-sectional approach, for the year 2010. From a total of 92959 visits in the Emergency Room (ER) of the “Clinical Emergency Hospital for Children “M.S. Curie”, Bucharest, 9258 patients were considered emergencies (group A) and 90 patients were major emergencies (group B). We performed 102 CT scans. Results were given as percentages. Results. The global percent of ER visits associated with a CT scan was 1% within the group A and it scored 1‰ from all ER visits. All patients from group B underwent a CT scan. Main indications were: major head injuries - 50%, intracranial hypertension – 35%, polytrauma – 12.7%, suspicions of malformations – 5.9%. The global detection rate for any kind of lesion was 51%. For brain trauma the rate scored 49%, identifying the following lesions: diffuse cerebral edema (19%), intracranial hemorrhage (15.6%), skull fractures (15.6%) and other facial or visceral lesions (29%). For intracranial hypertension the method’s sensitivity was 43%, for multiple trauma 84.6% and for malformations’ suspicions 100%. The lesions’ detection rate, for different clinical conditions (or the method’s sensitivity) is similar with other medical studies. Conclusion. In all pediatric patients, indication of a CT scan was made after a careful selection of cases. The method proved to be useful for managing all kind of trauma and intracranial hypertension situations.