bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigations on an All-Oxide Ceramic Composites Based on Al2O3 Fibres and Alumina–Zirconia Matrix for Application in Liquid Rocket Engines
Authors: Bach Christian , Wehner Frank , Sieder-Katzmann Jan
Published: November 2022

High performance ceramics, particularly Ceramic Matrix Composite (CMC) materials found their way into liquid rocket engines. Yet, so far, mainly carbide or nonoxide CMCs have been of interest. This paper explores the potential and challenges of oxide–oxide ceramic matrix composites (OCMCs) for application in rocket thrust chambers. Therefore, strength, leakage and hot gas tests are conducted with material samples. A particular focus lies on the application of coatings to seal the permeability inherent to the material. Furthermore, prototypes in the form of flame tubes, ceramic chambers with nozzles and ceramic chambers with graphite inlays are developed and investigated experimentally in test firings. The results show that a recrystallised glass of a Y-Al-Si-O compound can successfully create an impermeable coating of the OCMC without affecting its damag-tolerant behaviour. However, the prototype developments show that it is still very challenging to manufacture even slightly complex structures without critical failures. Nevertheless, OCMC structures of relatively simple geometries showed promising results in hot firings and could be used as a lightweight housing, while the inner contour of the chamber and nozzle are realised, e.g., by a graphite inlay of appropriate quality.
The Appropriate Particle Size of Dazomet Can Ensure the Soil Fumigation Effect from the Source
Authors: Zhang Daqi , Ren Lirui , Li Wenjing , Wang Qing , Liu Shenyan , Jin Xi , Fang Wensheng , Yan Dongdong , Li Yuan , Wang Qiuxia , Han Qingli , He Lin , Cao Aocheng
Published: November 2022

Dazomet (DZ) is a soil fumigant that has been used for decades at many countries, however it was reported to have caused phytotoxicity and reduced crop yield in many countries. In this experiment, in order to clarify whether the diameter of DZ is related to phytotoxicity, this research investigated the degradation rate of DZ with different diameter ranges under three soil types held at 15, 20 or 30% soil water content at 4, 15, 25 or 37 °C, and monitored concentrations of methyl isothiocyanate (MITC) produced when Shunyi soil was fumigated with DZ using the different particle sizes ranges. When the soil water content and temperature increased, the degradation rate of DZ with different particle sizes accelerated. However, the degradation rate of DZ with large particle sizes was still lower than small particle sizes. NO3−-N, available phosphorus (AP), available potassium (AK), pH and silt content in the soil were all significantly positively correlated with <100 μm DZ, and significantly negatively correlated with 300–400 μm and >400 μm DZ. However, organic matter (OM) and sand content produced the opposite result. The maximum concentration of MITC produced by 100–300 μm of DZ in 25 °C Shunyi soil at 30% water content were 102.2 mg/kg at 24 h. DZ produced peaks significantly higher and earlier at 30% than at 20% soil water content. We recommend selecting DZ manufactured with particle in the range of 100 to 300 μm, fumigating at about 25 °C and ensuring that about 30% soil water content is present in the soil immediately after fumigation.
Potato Slices Drying: Pretreatment Affects the Three-Dimensional Appearance and Quality Attributes
Authors: Bai Jun-Wen , Dai Yi , Wang Yu-Chi , Cai Jian-Rong , Zhang Lu , Tian Xiao-Yu
Published: November 2022

In the current study, the effects of steam blanching, saline immersion, and ultrasound pretreatment on the drying time, three-dimensional (3D) appearance, quality characteristics, and microstructure of potato slices were investigated. All the pretreatment methods enhanced the drying kinetics relative to the untreated potato slices. The 3D appearance was evaluated by reconstructed 3D images, shrinkage, and curling degree. The reconstructed images could well reproduce the appearance changes in the potato slices during drying. All the three pretreatment methods reduced the shrinkage during the drying process relative to the untreated potatoes. The curling degree was evaluated by the height standard deviation (HSD) of the material surface. The results showed that saline immersion inhibited the curling of the potato slices during the drying process, while ultrasound aggravated the curling of the potato slices. The potatoes treated by blanching obtained a lower total color difference (ΔE), higher total polyphenol content, and antioxidant capacity compared with the samples treated with saline immersion and ultrasound pretreatments. The observation of the microstructure by scanning electron microscope (SEM) verified the effects of the pretreatments on the drying time and appearance deformation. Therefore, it is of great significance to regulate the 3D appearance and quality characteristics of agricultural products during the drying process by an appropriate pretreatment.
Effects of the Decomposition of Mixed Plant Residues in Ecological Tea Garden Soil
Authors: Liu Shaqian , Yang Rui , Hou Chunlan , Guo Jiarui , Ma Juebing
Published: November 2022

(1) Background: Plant litter decomposition and its effect on soil nutrients are important parts of the ecosystem material cycle, and understanding these processes is key for species selection and allocation, to promote the effective use of litter in ecological tea gardens. (2) Methods: In situ decomposition was used in this study Changes in decomposition rate, element release, and soil properties during the decomposition of the mixed plant residues were measured. (3) Results: The decomposition rate (k) of the CCG (Camellia sinensis + Cinnamomum glanduliferum) mixed plant residue was significantly higher than that of the CS (Camellia sinensis) residue. The decomposition of the CCG, CPM (C. sinensis + Pinus massoniana), and CBL (C. sinensis + Betula luminifera) mixed plant residues showed an additive effect, whereas that of the CCL residue showed an antagonistic effect. The CBL mixed plant residue promoted the release of N; the decomposition of the CCG, CPM, CCL (C. sinensis + Cunninghamia lanceolata), and CBL residues promoted the release of TC (total carbon); and the decomposition of the CCG residue promoted the release of cellulose. After 428 d of decomposition, the four mixed plant residues had improved the soil nutrient contents to some extent. CCG and CBL residue decomposition resulted in greater improvements in soil nutrients. (4) Conclusions: The application of the mixture of material obtained by pruning C. glanduliferum, B. luminifera, and C. sinensis in an ecological tea garden accelerated the decomposition and nutrient release rates, increased soil nutrient contents, shortened the decomposition turnover period of plant residues, and accelerated the nutrient cycle of plant residues in the ecological tea garden.
Varietal Variances of Grain Nitrogen Content and Its Relations to Nitrogen Accumulation and Yield of High-Quality Rice under Different Nitrogen Rates
Authors: Wu Jiale , Que Renwei , Qi Wenle , Duan Gangqiang , Wu Jingjing , Zeng Yongjun , Pan Xiaohua , Xie Xiaobing
Published: November 2022

Nitrogen (N) management is an important strategy for improving the yield, grain quality, and N use efficiency of rice (Oryza sativa). Exploring appropriate N application rates is essential for high-quality rice production in China, especially in the context of the large extension of these varieties in recent years. Field experiments were conducted to study changes of grain N content and their correlations to yield and yield components using twenty high-quality rice varieties grown at three N application rates (105, 165 and 225 kg ha−1) in 2019 and 2020. Additionally, a micro-plot experiment based on 15N isotope tracing technique was also conducted with two contrasting high-quality rice varieties of Y-liangyou 911 and Yeiangyoulisi under two N application rates (165 and 225 kg ha−1) in 2021, with grain N accumulation, its subdivision, and N utilization investigated. We found that the grain N content of high-quality rice increased with the increase of N application rates, while there was no consistent response in grain yield. There was a significant quadratic relationship between grain yield and grain N content, while panicles m−2 and grain-setting rate had a positive and a negative correlation with grain N content, respectively, in both 2019 and 2020. Across three N application rates and two years, the coefficient of variation (CV) of grain N content ranged from 10.36% to 21.26% among twenty varieties, of which Y-liangyou 911 had the smallest CV, and six varieties, including Yexiangyoulisi, had the largest CV. The micro-plot experiment showed that, in comparison with N165, the grain N content, grain N accumulation, and N recovery rate increased under N225 in both varieties, but a significant increase in grain yield was only observed for Y-liangyou 911. Grain N accumulation derived from panicle N fertilizer and its ratios to total grain N accumulation and the N recovery rate was significantly higher than those derived from basal and tillering N fertilizers. Nevertheless, increasing N application rates had much greater effects on the grain N accumulation derived from basal and tillering fertilizers and on ratios to total grain N accumulation in Yexiangyoulisi than those in Y-liangyou 911. Our results suggested that adopting a moderate N application rate (165 kg ha−1) is conducive to maintaining an appropriate grain N content and achieving higher grain yield and N use efficiency as well as better quality of high-quality rice. Besides, moderately reducing basal and/or tillering N fertilizers is necessary for those varieties with a larger CV of grain N content.
Assessing the Effect of Irrigation Using Different Water Resources on Characteristics of Mild Cadmium-Contaminated Soil and Tomato Quality
Authors: Cui Jiaxin , Li Ping , Qi Xuebin , Guo Wei , Rahman Shafeeq Ur
Published: November 2022

As the world economy and society have developed quickly, the amount of farmland soil pollution has become alarming, which has seriously threatened global food security. It is necessary to take effective measures on the moderately contaminated soil to produce high-quality food and to protect food security worldwide by effective use of land resources. Our experimental design was to study the changes in soil physicochemical properties and tomato yield and quality indicators by irrigating tomatoes on cadmium-contaminated soil with two different water qualities (reclaimed water irrigation: RW; tap water irrigation: TW) through drip irrigation devices. Tomato quality indicators were determined using plant physiological assays, as well as vitamin C (VC), total acidity (TA), protein content (PC), and soluble sugar content (SS). We tested five different types of cadmium-contaminated soils (less than 0.60 mg/kg, 0.60–1.20 mg/kg, 1.20–1.80 mg/kg, 1.80–2.40 mg/kg, 2.40–3.00 mg/kg) against RW and TW, and performed high-throughput sequencing of the soils to obtain environmental results for soil microbial diversity. The results reveal that compared with the TW condition, soil nutritional status was increased with the irrigated RW. The yield of the tomatoes increased by 52.03–94.03% than TW. The results of the study showed significant and highly significant relationships between tomato quality indicators (TA, SS, yield) and soil physical and chemical properties indicators (p < 0.01, 0.05). For instance, the RW increased the SOM by 6.54–12.13%, the TP by 0.48–24.73%, the yield of the tomatoes by 52.03–94.03% than TW, while the cadmium content did not show significant differences (p < 0.05), and the cadmium content did not increase the soil’s pollution level. Compared with TW treatment, RW treatment alleviated the inhibition of soil microbial diversity by cadmium and RW also increased its soil microbial diversity. The relative abundance of Proteobacteria, Gemmatimonadetes, and Bacteroidetes in the RW condition were higher than in the TW condition at different cadmium concentrations. In conclusion, RW improved the overall quality conditions of soil and the diversity of microbial communities, and did not aggravate the pollution degree of cadmium-contaminated soil, and affected the yield of tomatoes positively. RW can be an effective irrigation technique to reduce the use of clean water.
Miscellaneous Sets of Abiotic Stresses and Plant Strategies to Cope with Them
Authors: Álvarez Sara , Acosta-Motos José Ramón
Published: November 2022

Plant stress can be defined as any adverse situation or agent that can damage or block the metabolism, growth or development of a plant [...]
Clinical Scoring Systems in the Newborn Calf: An Overview
Authors: Probo Monica , Veronesi Maria Cristina
Published: November 2022

A scoring system is an instrument that enables the scorers, including farmers, technicians, and veterinarians, to adopt a systematic approach for diagnosis or monitoring, as it decreases bias and confounding and increases objectivity. Practically, it is a number assigned to a patient that correlates with a probability that a diagnosis can be confirmed or that a specific outcome will follow. This article examines the clinical scores designed or adapted to bovine medicine that aim to assess newborn calf viability and to diagnose and monitor neonatal calf diarrhea and respiratory diseases, helping the clinician promptly recognize calves needing medical assistance. Despite the large number of clinical scores described in the literature, these are still barely used in farm animal practice; possibly, the complexity of the scores and missing recommendations for intervention are reasons for their lack of popularity as well as the crosswise lack of consistency among scores designed for the same purpose. Further research is needed in this regard to increase scores validation and encourage their application in bovine calf neonatology.
Cortisol in Manure from Cattle Enclosed with Nofence Virtual Fencing
Authors: Sonne Christian , Alstrup Aage Kristian Olsen , Pertoldi Cino , Frikke John , Linder Anne Cathrine , Styrishave Bjarne
Published: November 2022

To increase the efficiency and geographic expansion of nature conservation, large grazers have recently been used, either in the form of wild hoof-bearing animals or as domesticated ruminants including cattle. Using physical fencing limits migrating wildlife, while virtual fences encourage the animals to stay in the desired area without physical restrictions on wild animals. However, virtual fences raise ethical questions regarding the electric impulses emitted by the collar and stress in the fenced animals. Here, we tested if keeping twelve Angus cows (Bos Taurus) in a virtual fencing (Nofence©) compromised their welfare. For this purpose, we collected manure samples from five cows every second day prior to and after the transition from traditional to virtual fencing over a period of 18 days. Cortisol concentrations were 20.6 ± 5.23 ng/g w/w (mean ± SD), ranging from 12 to 42 ng/g w/w across individuals and concentrations did not change over the study period. We, therefore, conclude that there is no evidence suggesting that the cows were stressed from the use for virtual fencing, thus making virtual fencing a reasonable alternative to traditional electric physical fencing of cows.
Effect of Different Levels of Niacin on Serum Biochemical Parameters, Antioxidant Status, Cytokine Levels, Inflammatory Gene Expression and Colonic Microbial Composition in Weaned Piglets
Authors: Wang Zhaobin , Yi Zhenfeng , Wang Qiye , Yin Lanmei , Li Jun , Xie Junyan , Yang Huansheng , Yin Yulong
Published: November 2022

Niacin plays an important role in regulating the gut health of weaned piglets. In this study, 48 25-day-old weaned piglets (7.9 ± 0.20 kg) produced by 14 sows (3 to 4 piglets per sow) were randomly divided into 4 groups with 6 replicates in each group and 2 piglets in each replicate. Each group was fed diets supplemented with 22.5 (N1), 30 (N2), 45 (N3), and 75 (N4) mg/kg of niacin, respectively. Samples were taken at 7 and 14 d, respectively. The study shows that changes in niacin levels significantly affected the content of IgG and IgM in the serum (p < 0.05). Niacin had a significant effect on antioxidant parameters such as MDA, T-SOD, and CuZn-SOD in the jejunal mucosa of weaned piglets (p < 0.05). Moreover, significant differences were observed in the expression of cytokines such as TGF-β, TNF-α, and COX2 in the jejunal mucosa (p < 0.05). The 16S rRNA sequencing analysis showed that there were significant differences in the colonic species composition, which were also accompanied by changes in the isovaleric acid content (p < 0.05). In conclusion, an appropriate increase in niacin dose based on NRC (2012) has an important role in improving the antioxidant status of weaned piglets, alleviating intestinal inflammation in piglets, improving immunity, and regulating the structure of the microbiota.
Metabolomic Profiling of the Responses of Planktonic and Biofilm Vibrio cholerae to Silver Nanoparticles
Authors: Meza-Villezcas Anaid , Carballo-Castañeda Rommel A. , Moreno-Ulloa Aldo , Huerta-Saquero Alejandro
Published: November 2022

Vibrio cholerae causes cholera and can switch between planktonic and biofilm lifeforms, where biofilm formation enhances transmission, virulence, and antibiotic resistance. Due to antibiotic microbial resistance, new antimicrobials including silver nanoparticles (AgNPs) are being studied. Nevertheless, little is known about the metabolic changes exerted by AgNPs on both microbial lifeforms. Our objective was to evaluate the changes in the metabolomic profile of V. cholerae planktonic and biofilm cells in response to sublethal concentrations of AgNPs using MS2 untargeted metabolomics and chemoinformatics. A total of 690 metabolites were quantified among all groups. More metabolites were significantly modulated in planktonic cells (n = 71) compared to biofilm (n = 37) by the treatment. The chemical class profiles were distinct for both planktonic and biofilm, suggesting a phenotype-dependent metabolic response to the nanoparticles. Chemical enrichment analysis showed altered abundances of oxidized fatty acids (FA), saturated FA, phosphatidic acids, and saturated stearic acid in planktonic cells treated with AgNPs, which hints at a turnover of the membrane. In contrast, no chemical classes were enriched in the biofilm. In conclusion, this study suggests that the response of V. cholerae to silver nanoparticles is phenotype-dependent and that planktonic cells experience a lipid remodeling process, possibly related to an adaptive mechanism involving the cell membrane.
Recent Advances in the Application of Bacteriophages against Common Foodborne Pathogens
Authors: Hyla Kinga , Dusza Izabela , Skaradzińska Aneta
Published: November 2022

Bacteriophage potential in combating bacterial pathogens has been recognized nearly since the moment of discovery of these viruses at the beginning of the 20th century. Interest in phage application, which initially focused on medical treatments, rapidly spread throughout different biotechnological and industrial fields. This includes the food safety sector in which the presence of pathogens poses an explicit threat to consumers. This is also the field in which commercialization of phage-based products shows the greatest progress. Application of bacteriophages has gained special attention particularly in recent years, presumably due to the potential of conventional antibacterial strategies being exhausted. In this review, we present recent findings regarding phage application in fighting major foodborne pathogens, including Salmonella spp., Escherichia coli, Yersinia spp., Campylobacter jejuni and Listeria monocytogenes. We also discuss advantages of bacteriophage use and challenges facing phage-based antibacterial strategies, particularly in the context of their widespread application in food safety.
Antibiotic Use in Veterinary
Authors: Andres Manuel San
Published: November 2022

Since the introduction of antibiotics in the 1930s, the form and philosophy of their use has changed considerably [...]
Editorial: Antibiotics Special Issue on Pharmacokinetic/Pharmacodynamic Models of Antibiotics
Authors: Kebriaei Razieh , Berti Andrew D.
Published: November 2022

Pharmacokinetic/pharmacodynamic (PK/PD) modeling is an essential tool for rational drug development and treatment design [...]
Monofunctional Heme-Catalases
Authors: Hansberg Wilhelm
Published: November 2022

The review focuses on four issues that are critical for the understanding of monofunctional catalases. How hydrogen peroxide (H2O2) reaches the active site and outcompetes water molecules to be able to function at a very high rate is one of the issues examined. Part of the answer is a gate valve system that is instrumental to drive out solvent molecules from the final section of the main channel. A second issue relates to how the enzyme deals with an unproductive reactive compound I (Cpd I) intermediate. Peroxidatic two and one electron donors and the transfer of electrons to the active site from NADPH and other compounds are reviewed. The new ascribed catalase reactions are revised, indicating possible measurement pitfalls. A third issue concerns the heme b to heme d oxidation, why this reaction occurs only in some large-size subunit catalases (LSCs), and the possible role of singlet oxygen in this and other modifications. The formation of a covalent bond between the proximal tyrosine with the vicinal residue is analyzed. The last issue refers to the origin and function of the additional C-terminal domain (TD) of LSCs. The TD has a molecular chaperone activity that is traced to a gene fusion between a Hsp31-type chaperone and a small-size subunit catalase (SSC).
Ground Settlement of Deeply Buried Two-Lane Tunnels with Large Cross-Sections Using Different Construction Methods
Authors: Han Yugang , Wei Changming , Cui Mengyuan , Xie Hong , Ou Yangwang , Zhu Hao , Liu Taoying
Published: November 2022

To ensure the safety of excavations such as large section tunnels of the Guangxi Liubin Highway Tunnel Project, we implemented a simulation analysis of 3D tunnel models based on finite software for different construction methods. Different from the traditional simulation, this paper uses various construction methods to compare, study, and analyze the advantages and disadvantages of different excavation methods by combining them with the excavation. The feasibility of different construction methods was analyzed by studying the mechanical characteristics and settlement changes using the Cross Diaphragm (CRD), Center Diaphragm (CD), and full-section methods while building a large section tunnel. The arch perimeter deformation and surface settlement during the initial support and secondary lining proved that the CRD excavation method is the most favorable and causes the least damage to the stability of the surrounding rock. For the analysis of surface subsidence, the “V”-shaped surface subsidence curve excavated by the CRD method is the closest to the subsidence curve. However, we used the adjusted peak formula to fit the prediction formula for the surface settlement curve of the deep-buried two-lane tunnel with a large cross-section applicable to this project, which will provide an important reference for similar projects.
The Influence of Two Curing Protocols on the Colour Stability and Translucency of Resin Luting Agents
Authors: Monterubbianesi Riccardo , Vitiello Flavia , Tosco Vincenzo , Bourgi Rim , Putignano Angelo , Orsini Giovanna
Published: November 2022

The colour properties of resin luting agents (RLAs) can influence the aesthetic of an indirect restoration. This in vitro study aims to evaluate the colour stability and translucency of RLAs cured using two different protocols by means of a spectrophotometer. Six RLAs were investigated: Enamel Plus Flow (MF), Enamel Plus (MH), light-cure Nexus Third Generation (NX3L), dual-cure Nexus Third Generation (NX3D), RelyX Veneer (RXL) and RelyX Ultimate (RXD). The samples were randomly divided into two groups (n = 5) according to the curing protocol used: the traditional protocol (P1), in which the samples were cured for 40 s, and the step luting protocol (P2), in which samples were cured for 5 s. Then, after 20 s, they were cured again for an additional 40 s. Colour changes and differences in translucency were calculated before (t0) and 1 day (t1) and 7 days (t7) after immersion of the samples in distilled water. Data were analysed using one-way ANOVA, Tukey’s test for multiple comparisons and a t-test for paired comparisons (α = 0.05). The colour and translucency of the RLAs changed between t0 and t7 (p < 0.05). In particular, only RXD showed a visually perceptible difference in colour and translucency between P1 and P2 (p = 0.00). The results of this study suggest that, except for RXD, the curing protocol does not affect the colour or translucency of the tested RLAs, even if all these materials underwent perceptible changes in colour and translucency.
Design and Experimental Study of Intermittent Automatic Grouping Dropping Plug Seedling Mechanism of Fixed Seedling Cups
Authors: Chen Bin , Hu Guangfa , Sun Songlin , Xiao Mingtao , Sun Chaoran
Published: November 2022

In a vegetable transplanting operation, if the seedling picking mechanism extracts the whole row of seedlings, the seedling separating mechanism needs to place the seedlings in groups. In this study, a seedling separating mechanism based on a fixed seedling cup was proposed to realize faster seedling grouping in a smaller volume. A collision model between the pot and the wall of the seedling dropping cylinder during the seedling dropping process was established. The duration of seedling dropping at different positions was analyzed. Subsequently, the calculation equations between the installation angle and the cam rotation speed and the dropping duration were derived. The net dropping duration of seedlings at different positions was measured. According to the measurement results, the installation angles of the driving cam at each position were calculated as 0°, 72°, 150°, 216°, and 288°, respectively. The seedling uniformity test was conducted according to the optimized installation angles. The test results revealed that the success rate of dropping seedlings was 100%, the coefficient of variation in dropping seedling interval at different positions was 6.25%, and the matrix damage rate was less than 10%, which verified the reliability of the dropping seedling principle. Finally, the stability tests results showed that the mechanism was able to complete the uniform seedling drop operation at a seeding frequency of 75~108 plants/(min · row) under the existing installation conditions. Therefore, the research results can provide a reference for the design and research of a subsequent traction-based automatic pot seedling transplanting machine.
Frequency Stability Analysis of a Low Inertia Power System with Interactions among Power Electronics Interfaced Generators with Frequency Response Capabilities
Authors: Radaelli Lucio , Martinez Sergio
Published: November 2022

One of the main actions required to face and limit global warming is the substitution of conventional fossil-fueled electrical generators with renewable ones. Thus, it becomes fundamental to create non-dispatchable renewable generators able to provide services for power system stabilization that nowadays are delivered by conventional ones. Particularly, renewable generators are usually connected to the electrical power system through power electronic converters lacking natural responses to frequency variations. This challenges conventional frequency control methods that are based on synchronous generators’ capabilities, particularly in systems with high levels of non-synchronous generation. Solutions based on advanced controls that allow renewable generators to participate in frequency control are the subject of current research efforts worldwide. This paper contributes to these efforts by studying the benefits of introducing Power Reserve Control in photovoltaic generators and Extended Optimal Power Point Tracking control in wind generators to provide frequency control in low inertia power systems and the interactions between them. The tests and the simulations, prove that these kinds of controls help in stabilizing the system frequency thanks to the cooperative action of both types of renewable generators.
Fuzzy PID Control of the Three-Degree-of-Freedom Parallel Mechanism Based on Genetic Algorithm
Authors: Zhu Zhifang , Liu Yuanjie , He Yuling , Wu Wenhao , Wang Hongzhou , Huang Chong , Ye Bingliang
Published: November 2022

It is necessary to upgrade and transform the sorting equipment in the industrial production line. In order to improve production efficiency and reduce labor intensity, a high-speed lightweight parallel mechanism control system for the high-speed sorting and packaging of light items was studied. A fuzzy PID controller based on genetic algorithm (GA) optimization is proposed according to the nonlinear and strong coupling characteristics of the parallel mechanism (PM) control system. The inverse kinematic analysis was conducted to map the workspace trajectory tracking problem to the joint space. It was transformed into the trajectory planning and solving problems in the joint space. The motion trajectory was obtained utilizing quintic polynomial interpolation. Finally, the servo control system model was established, and the PID control parameters were optimized and self-tuned by the GA. They were applied to the fuzzy PID controller for simulation experiments. The simulation results showed that the GA-optimized fuzzy PID control system compared with the fuzzy PID control system had a 23.39% shorter rise time, 22.32% less regulation time, and 7.18% less steady-state error. The control system had a good dynamic and steady-state performance.
Diversity of Physical Processes: Challenges and Opportunities for Space Electric Propulsion
Authors: Levchenko Igor , Baranov Oleg , Pedrini Daniela , Riccardi Claudia , Roman H. Eduardo , Xu Shuyan , Lev Dan , Bazaka Kateryna
Published: November 2022

The renewed interest in space exploration has led to the growth in research efforts pertaining to advanced space propulsion systems, including highly efficient electric propulsion systems. Although already tested in space many decades ago and being currently employed on various space platforms and thousands of satellites, these systems are yet to reach their full potential for applications on orbit and in deep space. One specific feature of space electric propulsion is the large diversity of physical processes used in this technology, which is not typical for many other types of propulsion systems used in transport, such as those used by airplanes or automobiles. Various physical processes and mechanisms underpin different electric propulsion technologies and should be integrated to drive the future science and technology of space electric propulsion systems. This opinion article briefly highlights this feature of space electric propulsion and outlines some challenges and opportunities that follow from this diversity.
Characterization and Reactivity of Natural Pozzolans from Guatemala
Authors: Sierra Oscar M. , Payá Jordi , Monzó José , Borrachero María V. , Soriano Lourdes , Quiñonez Javier
Published: November 2022

The possibility of using pozzolanic materials as a partial substitute for Portland cement (PC) to develop mortars and concretes promotes environmental and economic benefits. The present paper includes an in-depth investigation into the characterization of natural pozzolans from Guatemala for the valorization of these materials. An exhaustive physico-chemical characterization of the starting materials was first carried out. Second, an analysis of the pozzolanic reactivity of both pozzolans was performed using an evolution test of the pH and electrical conductivity measurements and a Frattini test. Finally, pastes and mortars were manufactured with pozzolans T and R as a substitute for PC. The results of the pH and electrical conductivity measurements confirmed that natural pozzolans can be classified as low-reactivity. The Frattini test and the thermogravimetric analysis confirmed the pozzolanic behavior of natural pozzolans at 28 curing days. In the cement pastes, lime fixation was positive for a long curing period, which demonstrated that these pozzolans had medium–long-term pozzolanic activity, similar to fly ash (FA). The results were confirmed by mechanical assays. The mortars with 15%, 25%, and 35% substitutions of cement for pozzolans had strength gain percentages of around 13–15% at 90 curing days.
The Polychrome in Expression of Baroque Façade Architecture
Authors: Ludwig Bogna
Published: November 2022

The article is dedicated to the role of polychrome solutions of the architectonic order in shaping the mode of expression of Baroque façades. The ancient principles of designing architectural structures, inherited from the Renaissance, were subjected to reinterpretations in order to impart different expressive values. Vertical layouts began to dominate in the Baroque. Appropriately selected polychrome of the elements of the order could emphasize the compositional expression. The relationship between the layout of the polychrome in a given architectural order and the expression of a work of art has been established for some time. However, the generally available data on color schemes of architectural structures in Baroque buildings are still not fully organized. The paper analyzes examples of Baroque façades preserved in their original state and revalorized in recent years after thorough research by conservators in the field of architecture and color. The examples are mainly designed in the so-called great order, i.e., pertaining largely to church façades. The decisive field of change became the shaping of the coloristic decoration of the entablature.
Effects of Precipitation Change and Nitrogen and Phosphorus Additions on Traits and Abundance of Potentilla anserina in an Alpine Meadow
Authors: Wu Lin , Ren Yanmei , Wan Ji-Zhong , Wang Mengyan , Wang Zuoyi , Fu Feiyan , Sun Jianping , Fu Yanjin , Ma Zhen , Zhang Chunhui
Published: November 2022

Changes in precipitation patterns and eutrophication can cause changes in plant traits and abundance, potentially affecting plant community structure and functions. Here, we studied responses of traits and abundance of Potentilla anserina to precipitation change and nitrogen (N) and phosphorus (P) additions, and the effect of traits on its abundance in an alpine meadow of the Qinghai-Tibet Plateau. We found that precipitation change and N and P additions significantly affected the mean value of traits such as specific leaf area (SLA), leaf dry matter content (LDMC), single leaf area, plant height and individual size, while only P addition significantly affected intraspecific variation of SLA and individual size. Increased precipitation and N and P additions shifted plant traits to more resource acquisitive, and increased plant abundance. Responses of plant traits to P addition were larger than that of N addition. Plant abundance was mainly affected by precipitation, and was limited by N or P dependent on precipitation conditions. In conclusions, our research shows that P. anserina can respond to environmental changes by changing its traits to improve its adaptability, potentially affecting community structure and ecosystem functions.
A Comparative Analysis of Changes in Temperature and Precipitation Extremes since 1960 between China and Greece
Authors: Li Zhen , Shi Yingling , Argiriou Athanassios A. , Ioannidis Panagiotis , Mamara Anna , Yan Zhongwei
Published: November 2022

The temporal and spatial variations of 26 extreme temperature and precipitation indices for China and Greece were comparatively analysed. Also, their association with atmospheric circulation types was evaluated using multiple linear regression. The calculation of the extreme indices was based on homogenized daily temperature and precipitation time series from 1960 to 2010 for Greece and 2021 for China. Extreme precipitation, intensity, and short-term heavy precipitation increased, while persistent heavy precipitation has decreased since 1960 in China. Short-term heavy precipitation has also shown an increasing trend in Greece, though total precipitation and persistent heavy precipitation decreased there between 1960 and 2010. Extreme cold events have tended to decrease, and extreme warm events have increased in both countries, a fact that can be attributed to global warming. For comparison, climatic warming in China was mainly seen in the half year of winter, while the extreme indices relevant to cold seasons such as FD0 and ID0 presented a small trend in Greece. The observed changes in many climatic indices, including RX5day and WSDI in China and R20MM, RX5day, CDD, PRCPTOT and FD0 in Greece, could be partly explained by those of the main large-scale circulation types in the corresponding regions. The significant multiple correlation coefficients of the main circulation types were up to 0.53 for RX5day and 0.54 for WSDI in China, and 0.74 for PRCPTOT and 0.71 for R20MM in Greece. The relationships between climatic indices and circulation types were closer in Greece than in China, especially for the precipitation indices.
Grain-Size End-Members of Anguli-Nuur Lake Core Sediments: Evidence for Moisture Variability in Northern China since the Last Deglaciation
Authors: Li Junfeng , Liu Xingqi , Mao Xin , Yang Huiqing
Published: November 2022

The common methods used for grain-size analysis have their own deficiencies and limitations in terms of explaining the genesis of grain-size components. In this study, the end-member modeling analysis method is applied to multi-mode grain-size distributions of core sediment from Anguli-nuur lake to help to understand the sediment provenance, transport processes and sedimentary environment. Four optimal end-members are unmixed, and three transport-deposition processes are revealed, including the runoff, wave and aeolian processes. The humidity index synthesized by the runoff and aeolian end-members in the core sediment is used to reconstruct the humidity variability in the East Asian monsoonal domain since the last deglaciation. Our record shows that the patterns of humidity variability are coincidentally linked with the monsoonal precipitation index from the same core and stalagmite record in southern China. The Holocene optimum is identified in early and middle Holocene. In addition, a series of millennial- and multi-centennial-scale dry events documented in our record are well correlated with the ice-rafted debris events in the North Atlantic. The results reveal that the grain-size record from Anguli-nuur lake is sensitive in response to moisture variability in northern China.
Simultaneous Determination of Amino Acids and Biogenic Amines by Liquid Chromatography Coupled to Mass Spectrometry for Assessing Wine Quality
Authors: Navarro-Abril Ainhoa , Saurina Javier , Sentellas Sònia
Published: November 2022

Biogenic amines (BAs) and free amino acids (AAs) are low-molecular nitrogenous compounds occurring in a wide range of foodstuffs, found in increased amount in different fermented foods, seafood, and wines. This study deals with the development of an analytical method based on liquid chromatography with tandem mass spectrometry with precolumn derivatization with dansyl chloride for the determination of BAs and AAs in musts, wines, and sparkling wines. The resulting compositional profiles have been exploited as potential descriptors of quality and other oenological issues using chemometric methods including principal component analysis (PCA) and partial analysis of least squares-discriminants (PLS-DA). Proline is the most abundant compound, and other remarkable species are lysine, ethanolamine, tyramine, histamine, and putrescine. Fermented samples (wines and sparkling wines) are much richer in both BAs and free AAs than the initial musts. Significant differences have also been noticed in the quality, as the best products display, in general, lower levels. The dissimilarities in the content of the analytes between the two grape varieties studied (pinot noir and xarel·lo) and those dealing with quality aspects have made it possible to establish a tree to classify the samples based on these two features with excellent classification rates.
Challenges and Strategies for a Thorough Characterization of Antibody Acidic Charge Variants
Authors: Liu Y. Diana , Cadang Lance , Bol Karenna , Pan Xiao , Tschudi Katherine , Jazayri Mansour , Camperi Julien , Michels David , Stults John , Harris Reed J. , Yang Feng
Published: November 2022

Heterogeneity of therapeutic Monoclonal antibody (mAb) drugs are due to protein variants generated during the manufacturing process. These protein variants can be critical quality attributes (CQAs) depending on their potential impact on drug safety and/or efficacy. To identify CQAs and ensure the drug product qualities, a thorough characterization is required but challenging due to the complex structure of biotherapeutics. Past characterization studies for basic and acidic variants revealed that full characterizations were limited to the basic charge variants, while the quantitative measurements of acidic variants left gaps. Consequently, the characterization and quantitation of acidic variants are more challenging. A case study of a therapeutic mAb1 accounted for two-thirds of the enriched acidic variants in the initial characterization study. This led to additional investigations, closing the quantification gaps of mAb1 acidic variants. This work demonstrates that a well-designed study with the right choices of analytical methods can play a key role in characterization studies. Thus, the updated strategies for more complete antibody charge variant characterization are recommended.
A 17-Year Study of the Response of Populations to Different Patterns in Antlerless Proportion of Imposed Culls: Antlerless Culling Reduces Overabundant Deer Population
Authors: Suzuki Kei K. , Kuwano Yasumitsu , Yasuda Masatoshi
Published: November 2022

Increasing populations of large herbivores have caused environmental damage around the world, and it is necessary to improve population management strategies. Culling is a traditional management method. Antlerless deer proportions, consisting of adult female deer and fawn in Cervidae in wildlife statistics, are directly related to population increases; thus, the culling-based removal of individuals from habitats and the removal of these antlerless individuals by game hunting and nuisance control might be effective approaches for reducing population sizes. We evaluated the effectiveness of antlerless culling on 17-year density trends in the sika deer (Cervus nippon) population across an area of 1175 km2 in Fukuoka Prefecture (Japan). In 11 out of 47 grids (area measuring 5 by 5 km), the densities of sika deer tended to decline; meanwhile, in the remaining 36 grids, the densities increased. These density trends were explained by changes in the proportion of antlerless culling, as the densities declined with increasing proportions of antlerless deer. The results affirm the theory that antlerless culling is effective in population management; it is posited that antlerless-biased culling could be a crucial measure in managing overabundant populations of herbivores, contributing to more effective conservation of forest environments.
A Systematic Review and Meta-Analysis of the Association between the FV H1299R Variant and the Risk of Recurrent Pregnancy Loss
Authors: Capra Anna Paola , Ardizzone Alessio , Briuglia Silvana , La Rosa Maria Angela , Mondello Stefania , Campolo Michela , Esposito Emanuela
Published: November 2022

This study evaluated the association between the H1299R factor V (FV) variant (rs1800595) and recurrent pregnancy loss (RPL). Pubmed (MEDLINE) and Embase (OVID) bibliographic databases were searched from the inception to 31 May 2022 to identify suitable articles according to PRISMA and MOOSE guidelines. We included observational studies, case-control studies, cross-sectional studies, and cohort studies reporting a numerical and well-distinguished Het or Hom status of the H1299R variant obtained through PCR or other biochemical techniques and comparing RPL patients with a healthy control group. The review protocol was registered at PROSPERO (CRD42022330077). Two authors independently screened studies, extracted data, and carried out the risk of bias assessment using the Newcastle Ottawa scale (NOS). A meta-analysis was performed with RevMan software Version 5.4 using an odds ratio (OR) with an M-H, random effect, and 95% CI. We included 13 clinical studies for a total of 1669 RPL patients and 1466 healthy women as a control group. H1299R variant was slightly associated with RPL albeit without significance (OR 1.18, 95% CI: 0.78–1.80, p = 0.44). Subgroup analyses considering H1299R in heterozygosity (OR 1.13, 95% CI: 0.76–1.67, p = 0.56) and in homozygosity (OR: 2.11, 95% CI: 0.74–6.01, p = 0.16) revealed a similar trend. Lastly, we evaluated the association between H1299R and RPL based on the number of previous miscarriages (≥2 or ≥3). This comprehensive systematic review and meta-analysis sheds light on the specific influence of the H1299R variant in the F5 gene on RPL, constituting valid support for medical care during pregnancy and genetic counseling.
Tears as a Source of Biomarkers in the Diagnosis of Graves’ Orbitopathy
Authors: Bajkowska Diana , Szelachowska Małgorzata , Buczyńska Angelika , Krętowski Adam Jacek , Siewko Katarzyna
Published: November 2022

Thyroid eye disease (TED) is a poorly understood autoimmune manifestation of thyroid diseases most commonly associated with Graves’ disease. Due to a lack of specific biomarkers and uncertain signs and symptoms, Graves’ orbitopathy (GO) is challenging to diagnose early and treat effectively. Nowadays, there is great interest in searching for precise molecular biomarkers for early detection, disease monitoring, and clinical management. Researchers are keen to identify novel methods to predict and diagnose diseases and to monitor patient therapeutic response. Tears, due to their direct contact with the eye and the fact that lacrimal glands can also be affected by the disease, could give new insights into the mechanisms taking place in thyroid-associated orbitopathy (TAO) and reveal potential promising biomarkers. Tear fluid offers the possibility of the non-invasive acquisition of a sample with a high protein content, thereby attracting continuously growing interest in the discovery of novel biomarkers. This article provides an up-to-date overview of the various putative tear-fluid biomarkers that have been identified. In this review, we present the potential use of tears as a diagnostic fluid and tool to investigate the mechanism of ocular diseases and discuss the future research directions in this area.