bluuebunny/crossref_metadata_2025 huggingface dataset:
Moving Metaphors: Shifting Institutional Responsibilities and Evidentiary Boundaries in the Commissioning of Pre-Exposure Prophylaxis for HIV
Authors: Gee Seran , Chum Antony , Lim Bryan
Published: March 2019

In this article, we investigate how speakers in the U.K.’s House of Commons cited the same legislative context and medical research to arrive at contradictory conclusions regarding the Government’s responsibility to fund pre-exposure prophylaxis (PrEP) as an HIV intervention. Because the Government had expressed that it would not comment on institutional responsibilities directly, given the likelihood of a legal challenge in response to the National Health Service withdrawing PrEP from the drug commissioning process, the Government’s support of this decision could not be explicitly detailed. Our discourse analytic approach reveals how members of parliament adopted positions in the debate by using distinct metaphorical frames and lexical choices to linguistically encode assumptions that imply contrary interpretations of mutually agreed upon facts. This suggests that the concrete discursive practices used to cite evidence in policy-making discussions, regardless of the quality of the evidence, may have material consequences for evidence-based policy.
Effects of a Primary Palliative Care Educational System for Teaching Learners at Different Levels of Training
Authors: El-Sourady Maie , Chen Heidi , Martin Sara F. , Ritchie Joseph , Ellis Katreece , Richeson Ashley , Moore Don , Karlekar Mohana , Misra Sumi
Published: March 2019

Interest and appreciation for palliative care (PC) has resulted in increased demand for both PC services and education. The PC rotation has been shown to improve PC knowledge in medical students (MS) and internal medicine (IM) residents, and PC specialists stand poised to direct the primary PC education of learners at different levels of training. To concurrently teach learners of different levels of training on a busy PC service, we created an educational system that emphasizes management of learner schedules, organization of teaching activities, faculty development to improve teaching skills, and learner self-evaluation. Both MS and IM residents showed an improvement in self-assessed competence as well as increased comfort level with seriously ill patients after PC rotation. Careful adjustment of learner schedules has accommodated an increasing number of learners, while maintaining a low learner to faculty ratio. The PC educators face an exciting and daunting challenge as the number of patients with PC needs and the number of learners requesting PC experience grow. We continue to improve milestone-based PC assessment tools, to invest in faculty development, and to explore innovative ways to support PC educators as they strive to provide consistent PC education that is both useful for learners and can be incorporated into busy PC clinical practice.
Effect of Erythropoiesis-Stimulating Agent Therapy in Patients Receiving Palliative Care of Chronic Kidney Disease
Authors: Chow Kai Ming , Szeto Cheuk Chun , Choy Agnes Shin Man , Ng Jack Kit Chung , Mok Alice Ka Wai , Leung Chi Bon , Li Philip Kam Tao
Published: March 2019

Background:

Despite the increasing use of erythropoiesis-stimulating agent (ESA) in patients receiving dialysis, few studies have examined the benefits of ESA for patients with chronic kidney disease receiving palliative care.

Objective:

We designed a retrospective observational study to evaluate the effect of ESA in treating anemia of renal disease among adult patients receiving palliative care instead of dialysis. The primary objective was to assess whether ESA can reduce the transfusion burden and hospitalization.

Results:

Thirty-nine patients receiving ESA were matched with a control group of 39 patients without ESA. Their mean age and glomerular filtration rates were 76.7 (10.2) years and 11.6 (5.7) mL/min/1.73 m2, respectively. Baseline hemoglobin levels were comparable in the ESA and control groups; their corresponding values were 10.2 (1.5) and 10.1 (1.4) g/dL. During 1-year observation period, 34 units of red cell transfusion occurred in patients receiving ESA, whereas 128 units of red cell were transfused to patients in control group. Patients in the control group had higher transfusion rate (incidence rate ratio [IRR]: 3.63; 95% confidence interval [CI]: 2.49-5.31; P < .00001) and higher admission rates (IRR: 2.34; 95% CI: 1.80-3.03; P < .000001) than the ESA group even after adjustment for comorbidities.

Conclusions:

High disease burden of palliative care among patients with stage 4 to 5 chronic kidney disease was reflected by transfusion requirement and hospitalization rates, both of which were shown to be significantly ameliorated by ESA treatment.
Function of Lymphocytes in Oligodendrocyte Development
Authors: Tanabe Shogo , Yamashita Toshihide
Published: March 2019

Oligodendrocytes generate myelin sheaths to promote rapid neurotransmission in the central nervous system (CNS). During brain development, oligodendrocyte precursor cells (OPCs) are generated in the medial ganglionic eminence, lateral ganglionic eminence, and dorsal pallium. OPCs proliferate and migrate throughout the CNS at the embryonic stage. After birth, OPCs differentiate into mature oligodendrocytes, which then insulate axons. Oligodendrocyte development is regulated by the extrinsic environment including neurons, astrocytes, and immune cells. During brain development, B lymphocytes are present in the meningeal space, and are involved in oligodendrocyte development by promoting OPC proliferation. T lymphocytes mediate oligodendrocyte development during the remyelination process. Moreover, a subset of microglia contributes to oligodendrocyte development during the neonatal periods. Therefore, the immune system, especially lymphocytes and microglia, contribute to oligodendrocyte development during brain development and remyelination.
Plasma Levels of Vascular Endothelial Growth Factor and Selected Hemostatic Parameters in Association With Treatment Response in Multiple Myeloma
Authors: Sokol Juraj , Hrncar Matej , Nehaj Frantisek , Stasko Jan
Published: March 2019

Multiple myeloma (MM) is a neoplastic plasma cell disorder characterized by the clonal proliferation of plasma cells in the bone marrow and presence of monoclonal protein in the blood or urine. Diverse hemostatic abnormalities have been reported in patients with myeloma which predispose the patient to bleeding and also thrombosis. The aim of this study was to measure the concentrations of serum levels of vascular endothelial growth factor, D-dimer, and von Willebrand factor in patients with newly diagnosed or relapsed multiple myeloma before treatment, during therapy, and after successful therapy. The working hypothesis was that all of these factors reflect the total body burden of tumor. Angiogenic and coagulation activity should therefore decrease after successful therapy. Our study indicates that selected prothrombotic abnormalities occur in patients with MM, which may contribute to the increased risk of venous thromboembolism observed in these patients. The levels of our 3 parameters were strongly elevated in patient with newly diagnosed MM and also in patients with clinical stage III based on International Staging System criteria. Furthermore, there was a correlation between prognostic disease stages in all study population. It would be appropriate to include angiogenic and coagulation parameters into prognostic parameters.
The effect of mydriasis on moderate-to-high myopic eyes with implantable collamer lenses V4 and V4c
Authors: Zhu Yi , Zhang Jing , Zhu Haobin , Chen Jili , Zhou Jibo
Published: March 2019

Purpose:

To evaluate the vault change and anterior segment movement induced by mydriasis in moderate-to-high myopic eyes with implantable collamer lenses (ICL).

Setting:

Shanghai, China

Design:

A prospective consecutive observational study.

Methods:

A total of 45 eyes of 24 patients with ICL V4 implantation and 128 eyes of 65 patients with ICL V4c implantation were included and analyzed. Anterior chamber depth, posterior corneal endothelium-to-ICL distance, and vault before and after mydriasis were measured by Pentacam (Oculus, Wetzlar, Germany) at 1, 3, and 6 months after surgery.

Results:

Significant vault increases and anterior chamber depth increases induced by mydriasis were noted in both ICL V4 and V4c groups at 1, 3, and 6 months postoperatively. The corneal endothelium-ICL distance increased significantly in eyes with implanted ICL V4c after mydriasis at 3 and 6 months. Moreover, mydriasis-induced vault increases were greater in the ICL V4 group than in the ICL V4c group at 3 and 6 months. In eyes with implanted ICL V4c, mydriasis-induced vault increases were significantly greater at 1 month than at 3 and 6 months.

Conclusion:

Mydriasis results in a general vault increase in eyes with implanted ICLs. The adjustment of the pressure equilibrium via the central hole of the ICL V4c has an important role in vault change. The mydriasis-induced vault increases tend toward stability after 3 months postoperatively. Mydriasis is relatively safe in eyes with ICL implantation.
Coalitional Game Theory Facilitates Identification of Non-Coding Variants Associated With Autism
Authors: Sun Min Woo , Gupta* Anika , Varma Maya , Paskov Kelley M , Jung Jae-Yoon , Stockham Nate T , Wall Dennis P
Published: March 2019

Studies on autism spectrum disorder (ASD) have amassed substantial evidence for the role of genetics in the disease’s phenotypic manifestation. A large number of coding and non-coding variants with low penetrance likely act in a combinatorial manner to explain the variable forms of ASD. However, many of these combined interactions, both additive and epistatic, remain undefined. Coalitional game theory (CGT) is an approach that seeks to identify players (individual genetic variants or genes) who tend to improve the performance—association to a disease phenotype of interest—of any coalition (subset of co-occurring genetic variants) they join. This method has been previously applied to boost biologically informative signal from gene expression data and exome sequencing data but remains to be explored in the context of cooperativity among non-coding genomic regions. We describe our extension of previous work, highlighting non-coding chromosomal regions relevant to ASD using CGT on alteration data of 4595 fully sequenced genomes from 756 multiplex families. Genomes were encoded into binary matrices for three types of non-coding regions previously implicated in ASD and separated into ASD (case) and unaffected (control) samples. A player metric, the Shapley value, enabled determination of individual variant contributions in both sets of cohorts. A total of 30 non-coding positions were found to have significantly elevated player scores and likely represent significant contributors to the genetic coordination underlying ASD. Cross-study analyses revealed that a subset of mutated non-coding regions (all of which are in human accelerated regions (HARs)) and related genes are involved in biological pathways or behavioral outcomes known to be affected in autism, suggesting the importance of single nucleotide polymorphisms (SNPs) within HARs in ASD. These findings support the use of CGT in identifying hidden yet influential non-coding players from large-scale genomic data, to better understand the precise underpinnings of complex neurodevelopmental disorders such as autism.
Autism severity, co-occurring psychopathology, and intellectual functioning predict supportive school services for youth with autism spectrum disorder
Authors: Rosen Tamara E , Spaulding Christine J , Gates Jacquelyn A , Lerner Matthew D
Published: March 2019

Supportive school services are a primary service modality for youth with autism spectrum disorder. Autism spectrum disorder, as well as co-occurring psychiatric symptoms and low intellectual abilities, interfere with academic achievement and therefore influence decisions about school services. Therefore, we examined the association of parent, teacher, and clinician ratings of autism spectrum disorder and co-occurring psychiatric symptom severity and intellectual functioning with school services. In total, 283 youth with autism spectrum disorder were assessed with clinical evaluation via the Autism Diagnostic Observation Schedule and parent and teacher versions of the CASI-4R ( Child and Adolescent Symptom Inventory). Full Scale Intelligence Quotient scores were obtained from case records. Clinical and teacher evaluations of autism spectrum disorder severity predicted services and were more strongly associated with school services than parent ratings. Teacher ratings were only associated with common school services (e.g. speech/language therapy, occupational therapy, and/or social skills training) frequency at medium and high levels of clinician-rated autism spectrum disorder severity. Higher IQ and parent-rated externalizing symptoms predicted lower likelihood of receiving school services, whereas internalizing symptoms were not predictive of school services. Autism spectrum disorder symptoms may overshadow externalizing and internalizing symptoms when considering school service supports. Results highlight the importance of evaluating autism spectrum disorder severity via multiple sources, especially in cases of unclear symptom presentation, when examining correlates of school services for youth with autism spectrum disorder.
Separate contributions of autistic traits and anxious apprehension, but not alexithymia, to emotion processing in faces
Authors: Stephenson Kevin G , Luke Steven G , South Mikle
Published: March 2019

Reduced eye fixation has been commonly reported in autistic samples but may be at least partially explained by alexithymia (i.e., difficulty understanding and describing one’s emotional state). Because anxiety is often elevated in autism, and emotion-processing differences have also been observed in anxious samples, anxiety traits may also influence emotion processing within autism. This study tested the contribution of dimensional traits of autism, anxious apprehension, and alexithymia in mediating eye fixation during face processing. Participants included 105 adults from three samples: autistic adults (AS; n = 30), adults with clinically elevated anxiety and no autism (HI-ANX; n = 29), and neurotypical adults without elevated anxiety (NT; n = 46). Experiment 1 used an emotion identification task with dynamic stimuli, while Experiment 2 used a static luminance change detection task with emotional- and neutral-expression static photos. The emotions of interest were joy, anger, and fear. Dimensional mixed-effects models showed that autism traits, but not alexithymia, predicted reduced eye fixation across both tasks. Anxious apprehension was negatively related to response time in Experiment 1 and positively related to eye fixation in Experiment 2. Attentional avoidance of negative stimuli occurred at lower levels of autism traits and higher levels of worry traits. The results highlight the contribution of autism traits to emotional processing and suggest additional effects of worry-related traits.
Analyzing the legal roots and moral core of digital consent
Authors: Edenberg Elizabeth , Jones Meg Leta
Published: March 2019

We will argue that clarifying the “moral core” of consent offers a common metric by which we can evaluate how well different legal frameworks are able to protect the central moral rights and interests at stake. We begin by revisiting how legal frameworks for digital consent developed in order to see where there may be common moral ground and where these different cultures diverge on the issue of protection of personal information. We then turn to ethics to clarify the central interests and rights at stake in morally transformative consent, in order to provide a common basis for evaluating the different legal frameworks. Ultimately, we seek the moral core of digital consent in order to reimagine its role in international conflicts.
The corporate cultivation of digital resignation
Authors: Draper Nora A , Turow Joseph
Published: March 2019

The aim of this article is to propose a theoretical framework for studying digital resignation, the condition produced when people desire to control the information digital entities have about them but feel unable to do so. We build on the growing body of research that identifies feelings of futility regarding companies’ respect for consumer privacy by suggesting a link between these feelings and the activities of the companies they benefit. We conceptualize digital resignation as a rational response to consumer surveillance. We further argue that routine corporate practices encourage this sense of helplessness. Illuminating the dynamics of this sociopolitical phenomenon creates a template for addressing important questions about the forces that shape uneven power relationships between companies and publics in the digital age.
Delivering a better natural environment? The Agriculture Bill and future agri-environment policy
Authors: Rodgers Christopher
Published: March 2019

This article reviews the options for delivering a new approach to agricultural support post-Brexit, and in particular the development of a new approach to delivering environmental protection and biodiversity improvement through future farming policy. It considers the options for developing a policy based on 'public money for public goods', and argues for the development of an approach based on payment for the ecosystem services provided by land management and by farming. If a 'payment for ecosystem services' approach is to be successful, however, careful consideration must be given to the reform of land tenure law in order to secure a stable platform for the long term management of ecosystems and landscapes. And new legal models will be needed for capturing multi-party obligations for the purchase and sale of ecosystem services. Brexit offers many opportunities for developing a new and innovative approach to agri-environmental policy, but the development of a market for the sale and purchase of the important ecosystem services provided by agriculture will present significant challenges.
News coverage of human rights: Investigating determinants of media attention
Authors: Maier Scott R
Published: March 2019

In an empirical assessment of determinants of international news, this study tests the theory that human rights abuses elicit media attention commensurate to the violence. To evaluate this proposition, the study draws on two authoritative human rights indices: the Political Terror Scale and the Cingranelli–Richards human rights score. These indices are correlated country by country with a 180-nation database tracking foreign news coverage by the New York Times, Time magazine, and NBC Nightly News. Making a contribution to this field of research, this cross-media study assesses the magnitude of human rights suffering relative to the influence of economic, geographical, and demographic factors that drive media agenda setting. By informing the public of human suffering, media potentially provide a crucial link to political response and public policy. How well do the US media studied perform this role? Not very well. Results indicate that human rights abuse is a weak predictor of media attention; military and economic factors predominate international news coverage. With human rights ranked 7th of 16 news determinants, the study suggests that greater media attention can – and should – be given to victims in dire distress.
“International Migration” between empire and nation. The statistical construction of an ambiguous global category in the International Labour Office in the 1920s
Authors: Stricker Yann
Published: March 2019

This article inquires into the historical conditions of the global category of “international migration” by analysing quantification processes in the International Labour Organization in the 1920s. Based on a history of knowledge perspective, it analyses how and why the categories of immigration and emigration were reduced to the single category of “international migration”. The paper interprets this epistemological change with a shift from an imperial to an international point of view that occurred in the 1920s. This argument is based on an analysis of negotiations between international administrators and functionaries of the British Empire that arose, when international categorisation and quantification of people on the move began. Drawing on sources from the British National Archives and the International Labour Organization, this article highlights the historical importance of debates about the categories of “nation” and “race”, in the making of what was stabilized only later in the 20th century as the category of “international migration”.
The sublime attraction of active volcanoes: An exploration of tourists’ experiences during a long-distance hiking route in Iceland
Authors: Heimisdóttir Þórhildur , Sæþórsdóttir Anna Dóra , Gísladóttir Guðrún
Published: March 2019

This article attempts to understand the value and meaning of a hazardous natural environment for tourists. It focuses on the attraction of volcanic sites in the eyes of sensation-seeking hikers. The research is based on a participatory observation study and in-depth interviews with 11 hikers on the Laugavegur hiking trail, in the Highlands of Iceland. The research questions addressed in this article are, do hikers experience a threat from the natural environment, and does a hazardous environment contribute to a feeling of the sublime? In support of the theories put forth in the article about sensation seekers, risk perception, its heuristic traps and sublime feeling, the article argues that tourists perceive risks in the hazardous environment in a positive way, as something spectacular, unique and sublime. Thus, their positive risk perception of existing potential environmental hazards encourages tourists to ignore signs of risks and hazards and subsequently puts them in unnecessary danger.
Lice work: Non-human trajectories in volunteer tourism
Authors: Benali Amira , Ren Carina
Published: March 2019

This article studies volunteer tourism by following the trajectories of a non-human actor. Based on fieldwork at a Nepalese orphanage and drawing on insights from the material semiotics of Actor–Network Theory, we describe how the louse interferes as an unexpected actor with volunteer tourism at the orphanage. This post-human approach decentres the volunteer and destabilises the host–guest binary while adding to our understanding of tourism practices as complex and materially distributed endeavours. We analyse two configurations of head lice enacted through a modern morality of hygiene and Nepalese everyday life and show how they are deployed, contested and reconfigured onsite by volunteer tourism actors. By exploring patterns of absence and presence and using the concept of ontological choreography as an analytical resource, we show how the situated lice work of human and non-human actors at the orphanage offers new ways to grasp the forging of volunteer experiences and subjectivities.
From coal to cool: Reordering nature in post-Soviet Kyrgyzstan
Authors: Sturød Anne Gry
Published: March 2019

The article studies the transformation of a Kyrgyz coal-mining village into a tourism destination. By combining political ecology research approaches with concepts borrowed from Actor Network Theory (ANT), I attempt to show how nature-based tourism development contributes to a reordering of nature in certain ways rather than others. Supported by my empirical material, I suggest that this reordering of nature makes certain realities emerge, while others submerge. However, while some orderings of natures appear to be representing reality, it does not necessarily rule out multiple understandings of how nature “ought to look” or be used.
Disciplining thought: Between ideology and anything goes
Authors: Standish Paul
Published: March 2019

Educational research is subject to orthodoxies of old and novel kinds. The ‘foundations’ approach risks becoming stuck in footnotes to received ideas, while new-fangled disciplines seek to legitimate themselves in jargon and deference to new ‘authorities’. The critical deficit in both tendencies obstructs responsible enquiry. I begin by sketching the weaknesses and the potential of the foundations approach and go on to identify a range of threats to this potential. The first and major concern is the rise of empiricism, understood as the view that it is only through empirical enquiry that research into education can take place. A second concern is the dominance of English in educational research, in relation not only to the inevitable unfairness this brings in opportunities for publication but also to the substance of thought and enquiry. Exploration of the key terms in David Bridges’ ‘“Rigour”, “discipline” and the “systematic” in educational research’: and why they matter’ (this issue) frames the discussion, raising questions of inter- and multi-disciplinarity. There is an internal relation between discipline, rigour and coherence, and these, though not systematicity, are requirements of argument. The notion of disciplined thought is prised apart from distorted conceptions of rigour and over-reliance on procedure.
Pediatric Donor Management Goals in Use by US Organ Procurement Organizations
Authors: Ream Robert S. , Clark Matthew G. , Armbrecht Eric S.
Published: March 2019

Introduction:

A recent study of pediatric organ donation after the neurologic determination of death (DNDD) demonstrated an association between the use of donor management goals (DMGs) by organ procurement organizations (OPOs) and organ yield.

Objective:

To describe the pediatric DMGs used by OPOs and any association between specific DMGs and organ yield.

Design:

Query of US OPOs who utilized DMGs in the care of pediatric DNDD organ donors from 2010 to 2013.

Results:

All 23 OPOs using DMGs for pediatric DNDD organ donors during the study period participated (100%). The OPOs pursued an average 9.6 goals (standard deviation: 3.9; range: 5-22) with 113 unique definitions that targeted 33 aspects of donor hemodynamics, gas exchange/mechanical ventilation, electrolytes/renal function, blood products, thermoregulation, and infection control. The DMGs used by >50% of OPOs included blood pressure, oxygenation (partial pressure of arterial oxygen (PaO2), oxygen saturation of hemoglobin by pulse oximetry, or PaO2/fractional concentration of inspired oxygen [FiO2] ratio), pH, central venous pressure, serum sodium, urine output, limitations on inotropic support, and serum glucose. There was no significant correlation between the number of DMGs pursued by OPOs and organ yield. There was a difference in the observed/expected organs transplanted in the 0- to 10-year age-group for OPOs that included serum creatinine among their DMGs ( P = .046).

Conclusions:

The pediatric DMGs used by OPOs were generally measurable but diverse in definition and the number of goals pursued. There was no benefit in organ yield from larger DMG bundles. There may be a benefit in organ yield through the use of serum creatinine as a DMG in pediatric donors aged 0 to 10 years.
Glucose–insulin stabilization in type-1 diabetic patient: A uniform exact differentiator–based robust integral sliding mode control approach
Authors: Alam Waqar , Khan Qudrat , Ali Riaz Raja , Akmeliawati Rini
Published: March 2019

Diabetes mellitus is a persistent metabolic syndrome caused by impaired capability of the body’s production and usage of insulin. This impaired capability results in chronic hyperglycaemia, the elevated glucose concentration in the bloodstream, which may lead to many incurable complications. To escape this dire situation, a proper model-based exogenous infusion of insulin bolus is required, which is usually established via different feedback control strategies. In this article, the authors present a mathematical model–based robust integral sliding mode control approach for stabilization of internal glucose–insulin regulatory system in type-1 diabetic patient. Since the state variables of the system are not directly available to the controller, a uniform exact differentiator observer is employed to accomplish the aforementioned task. In the proposed control law, the incorporation of integral term in the switching manifold eliminates the reaching phase, which causes the sliding mode to establish from the very initial point, thus enhances the robustness property of the proposed control scheme. Moreover, the chattering problem is also substantially suppressed to a considerable extent along a defined manifold. To verify the theoretical analysis, the proposed control law is verified via computer simulations which demonstrate the effectiveness of the proposed control law against the external perturbations, that is, unannounced meal intake and physical exercise.
What Do We Tell the Drivers? Toward Minimum Driver Training Standards for Partially Automated Cars
Authors: Casner Stephen M. , Hutchins Edwin L.
Published: March 2019

Each year, millions of automobile crashes occur when drivers fail to notice and respond to conflicts with other vehicles, bicyclists, and pedestrians. Today, manufacturers race to deploy automation technologies to help eliminate these mishaps. To date, little effort has been made to educate drivers about how these systems work or how they affect driver behavior. Driver education for automated systems amounts to additional pages in an owner’s manual that is known to be a seldom-used glove box reference. In this article, we review the history of automation deployed in the airline cockpit decades ago. We describe how automation helped avoid many common crash scenarios but at the same time gave rise to new kinds of crashes. It was only following a concerted effort to educate pilots about the automation, about themselves, and about the concept of a human-automation team that we reached the near-zero crash rate we enjoy today. Drawing parallels between the automation systems, the available pilot and driver research, and operational experience in both airplanes and automobiles, we outline knowledge standards for drivers of partially automated cars and argue that the safe operation of these vehicles will be enhanced by drivers’ incorporation of this knowledge in their everyday travels.
Nonunion and Reoperation After Ulna Shortening Osteotomy
Authors: Verhiel Svenna H. W. L. , Özkan Sezai , Eberlin Kyle R. , Chen Neal C.
Published: March 2019

Background: The primary purpose of our study was to identify factors associated with reoperation after ulna shortening osteotomy. Our secondary aims were to determine the rate and type of reoperation procedures. Methods: In this retrospective study, we included patients older than 18 years of age who underwent an ulna shortening osteotomy between January 2003 and December 2015. Medical records of patients were assessed for our explanatory variables, reoperations, and reporting of symptoms. We used bivariate and multivariable analyses to identify factors associated with reoperation after ulna shortening osteotomy. Results: Among 94 patients who underwent 98 ulna shortening osteotomies, there were 34 reoperations (35%). Nineteen patients (19%) underwent removal of hardware, 6 (6.1%) had a nonunion, and 9 (9.2%) underwent additional surgeries. Surgery on their dominant limb, trauma, and prior surgery to the ipsilateral wrist were associated with reoperation. In multivariable analysis, factors independently associated with reoperation were the dominant side being affected (odds ratio = 3.9; 95% confidence interval [CI] = 1.36-11) and traumatic origin (odds ratio = 3.4; 95% CI = 1.1-11). Bivariate analysis identified younger age and prior surgery of the affected wrist as factors associated with hardware removal. More operations for refixation due to nonunion of osteotomy were performed in patients with a transverse osteotomy compared with patients with an oblique osteotomy. Conclusions: One in 3 patients will undergo a reoperation after ulna shortening osteotomy, most often due to hardware irritation or nonunion of osteotomy. Awareness of these rates and predictive factors may be helpful for preoperative discussions and surgical decision making.
Framing the migration: A study of news photographs showing people fleeing war and persecution
Authors: Greenwood Keith , Thomson TJ
Published: March 2019

Human migration due to political upheaval is rapidly accelerating, yet scholarly attention to refugees' visual news representations has lagged. Using a visual analysis informed by the transnational writings of Yuval-Davis related to the politics of belonging and the peace/conflict frame literature, 811 images primarily depicting migration from Turkey into Europe in 2015 and submitted to the Pictures of the Year International competition were examined. Analysis determined that, despite billions of dollars in aid and millions of migrants who have benefited from food assistance and other development opportunities, the photographers overwhelmingly highlighted the migrants' transitory nature, vulnerability and differences while minimizing any attempt to depict the shared connections or integrations that were occurring. As media are orienting devices, this has profound implications for how migrants are regarded on both the individual as well as the collective levels.
Relative health-related quality of life after treatment of unruptured intracranial aneurysms: long-term outcomes and influencing factors
Authors: Dammann Philipp , Wittek Paula , Darkwah Oppong Marvin , Hütter Bernd-Otto , Jabbarli Ramazan , Wrede Karsten , Wanke Isabel , Mönninghoff Christoph , Kaier Klaus , Frank Benedikt , Müller Oliver , Kleinschnitz Christoph , Forsting Michael , Sure Ulrich
Published: March 2019

Health-related quality of life (HRQOL) is an important clinical outcome parameter. Its analysis is particularly meaningful to patients with minor functional impairment. The main goal of this study was to assess long-term data of HRQOL and their variables for patients undergoing treatment for unruptured intracranial aneurysms (UIAs). Therefore, a cross-sectional study of HRQOL (SF-36 questionnaire) was conducted in patients treated for UIA using a telephone survey assessing numerous medical and sociodemographic variables. A total of 96 patients with a follow up longer than 36 months post-treatment were included. HRQOL results were compared with the German reference population. Uni- and multivariate analyses were performed to detect variables with an impact on outcome. After a mean follow up of 57.75 ± 13.56 months, patients with treated UIAs showed a significant decrease in the mental health domains ‘role emotional’ and ‘social functioning’ and the ‘mental health component score’ (MHCS) compared with the age- and sex-matched reference population. Overall, 47% of the patients showed a clinically and psychosocially relevant decrease compared with the mean MHCS of the reference population. Multivariate analysis suggests that mainly the treatment modality (coiling versus clipping) and additional remaining untreated UIAs negatively impacted mental HRQOL. In conclusion, the partly significant losses in HRQOL identify the necessity for less-wearing treatment strategies and a better prediction of risk of UIA rupture. Our results indicate that certain factors in the guidance and management of patients undergoing endovascular treatment may negatively affect their mental HRQOL. The relevance of additional UIAs remaining untreated on HRQOL is a new finding that should be considered in the counseling of patients with multiple UIAs.
12 Components of a Strong Vision Health System of Care: Components 1 and 2—Family Education and Comprehensive Communication/Approval Process
Authors: Nottingham Chaplin P. Kay , Baldonado Kira , Bergren Martha Dewey , Lyons Stacy Ayn , Murphy M. Kathleen , Bradford Geoffrey E.
Published: March 2019

The National Center for Children’s Vision and Eye Health (NCCVEH) at Prevent Blindness partnered with the National Association of School Nurses (NASN) to provide guidance for school nurses responsible for screening the vision of preschool and K–12 students. Goals of this national partnership are to (1) standardize approaches to vision health, (2) facilitate follow up to eye care for students who do not pass vision screening, (3) provide family/caregiver friendly educational information, and (4) consult with leading pediatric eye care experts to promote evidence-based best practices. The NCCVEH/NASN partnership created a Vision and Eye Health page on the NASN website ( https://www.nasn.org/nasn-resources/practice-topics/vision-health ). This resource is organized according to the 12 Components of a Strong Vision Health System of Care. The 12 components emerged as the NCCVEH considered vision screening from a systems perspective. This systems perspective addresses key activities along the entire spectrum of care that supports a child’s vision health—beginning with parent/caregiver education and ending with an annual evaluation of the school’s vision health system. Each of these 12 components will be described in 4 installments of NASN School Nurse in 2019. This installment describes the first two components: Family Education and a Comprehensive Communication/Approval Process.
Organizational Culture and Performance: Evidence From Microfinance Institutions in Kenya
Authors: Joseph Owino O. , Kibera Francis
Published: March 2019

The study aimed at determining the influence of organizational culture on the performance of microfinance institutions in Kenya. A descriptive cross-sectional survey design was adopted. Secondary data were collected from annual reports by the Association of Microfinance Institutions in Kenya and the Microfinance Rating Africa. Primary data were collected using structured questionnaire targeting the chief executive officer, human resource manager, and marketing manager. Data were analyzed using factor analysis and hierarchical regression. Our analysis identifies clan and hierarchy as the dominant cultural typologies in the microfinance industry. The results obtained demonstrate that organizational culture has a significant influence on non market performance. In addition, market culture is inversely associated with debt/equity ratio. We conclude that organizational culture is a major source of sustainable competitive advantage in the microfinance industry. Furthermore, we conclude that market culture promotes financial independence and sustainability in the long term.
Feasibility and preliminary effects of an integrated hospital-to-home transitional care intervention for older adults with stroke and multimorbidity: A study protocol
Authors: Markle-Reid Maureen , Valaitis Ruta , Bartholomew Amy , Fisher Kathryn , Fleck Rebecca , Ploeg Jenny , Salerno Jennifer , Thabane Lehana
Published: March 2019

Background:

Stroke is a major life-altering event and the leading cause of death and disability in Canada. Most older adults who have suffered a stroke will return home and require ongoing rehabilitation in the community. Transitioning from hospital to home is reportedly very stressful and challenging, particularly if stroke survivors have multiple chronic conditions. New interventions are needed to improve the quality of transitions from hospital to home for this vulnerable population.

Objectives:

The primary objective of this study is to examine the feasibility of implementing a new 6-month transitional care intervention supported by a web-based app. The secondary objective is to explore its preliminary effects.

Design:

A single arm, pre/post, pragmatic feasibility study of 20–40 participants in Ontario, Canada. Participants will be community-dwelling older adults (≥55 years) with a confirmed stroke diagnosis, ≥2 co-morbid conditions, and referred to a hospital-based outpatient stroke rehabilitation centre. The 6-month transitional care intervention will be delivered by an interprofessional (IP) team and involve care coordination/system navigation, self-management education and support, home visits, telephone contacts, IP team meetings and a web-based app. Primary evaluation of the intervention will be based on feasibility outcomes (e.g. acceptability, fidelity). Preliminary intervention effects will be based on 6-month changes in health outcomes, patient experience, provider experience and cost.

Conclusions:

Information on the feasibility and preliminary effects of this newly-developed intervention will be used to optimize the design and methods for a future pragmatic trial to test the effectiveness and implementation of the intervention in other contexts and settings.
Recommendations From Cognitive Psychology for Enhancing the Teaching of Natural-Science Categories
Authors: Nosofsky Robert M. , McDaniel Mark A.
Published: March 2019

Because of their complex structures, many natural-science categories are difficult to learn. Yet achieving accuracy in classification is crucial to scientific inference and reasoning. Thus, an emerging theme in cognitive-psychology and cognitive-science research has been to investigate better ways to instruct about categories. This article briefly reviews major findings that will help inform policies for teaching categories in the science classroom. Many of the examples come from our specific project that examines teaching rock classifications in the geologic sciences. This project uses formal models of human category learning—developed in cognitive psychology—to search for optimal teaching procedures. The model-suggested category-teaching procedures often lead to better learning outcomes than do alternative procedures motivated by teachers’ and students’ intuitive judgments. In addition to reviewing these enhanced procedures for teaching natural-science categories, the article points to recent broader efforts for fostering collaborations between cognitive-science researchers and education researchers.
Evaluating the Benefits of Conscious and Unconscious Thought in Complex Decision Making
Authors: Abadie Marlène , Waroquier Laurent
Published: March 2019

Decision-making research reports mixed findings about the best way to make complex decisions involving multiple criteria. While some researchers emphasize the importance of conscious thought to make good decisions, others encourage people to stop thinking and trust their snap judgments. Still others recommend a distracting activity prior to making a choice, assuming that unconscious processing of the decision problem occurs during distraction. We review studies comparing these three decision modes. We show that conscious deliberation helps people to make good decisions when people have in mind precise verbatim information about the exact features of each alternatives. By contrast, a distraction period is more useful when meaning-based gist representations of the alternatives are accessible. Finally, while a period of distraction or deliberation is beneficial for decision making under certain conditions, to blindly follow one’s gut feeling is never the right solution.
Decision Making and Alcohol: Health Policy Implications
Authors: Davis-Stober Clintin P. , McCarty Kayleigh N. , McCarthy Denis M.
Published: March 2019

Many negative outcomes associated with alcohol consumption stem from individual decision making, such as the decision whether or not to drive after drinking. Understanding biases in decision making as they relate to alcohol, and measuring variability in decision strategies across individuals, can be a tool for improving policy. For alcohol-related policy, both addiction and the acute effects of intoxication are potential sources of bias or heterogeneity in decision strategy, and we provide a brief primer on how they can affect decision making. We then discuss two alcohol policy domains, alcohol impaired driving and excessive consumption. We review potential implications of major findings in decision-making research for each of these domains, and point out how policy could take account of biases and variability in decision making.
Making marijuana an environmental issue: Prohibition, pollution, and policy
Authors: Polson Michael
Published: March 2019

Over the past two decades, activists and market actors have successfully liberalized marijuana consumption and distribution in most US states. Given ongoing federal supply-side interdiction strategies, however, production has been another matter. This article traces the emergence of marijuana cultivation as an environmental matter. “The environment” increasingly constitutes a material-discursive social field into which actors (e.g. activists, law enforcement, producers, conservationists) can launch interventions into productive processes. The article traces three early, formative interventions in northern California: by federal agents to “reclaim” and protect public lands; by a county government to discipline and segregate compliant environmental citizens from recalcitrant, racialized “criminals”; and by producers themselves to mobilize environmental discourses in regulatory debates. Amidst ideas of pollution, reclamation, stewardship, and sustainability, these projects revalorized marijuana production, articulating with and departing from entrenched systems of inequality and stigma. As marijuana production liberalizes, this article draws attention to the legacy of prohibition moralities in regulatory debates, the necessity of incorporating criminalized actors in civil regulation and knowledge formation, and the possibility for a liberation environmentality that exceeds the terms of exploitative, extractive relations that dominate contemporary agriculture, land use, and drug policy.
Wildness as vitality: A relational approach
Authors: Vannini Phillip , Vannini April S.
Published: March 2019

Countless authors have deconstructed both the romantic and the troubled history of wildness and wilderness, yet very few researchers have ever asked people: “What does wild mean to you?” In doing so, with our research we aim to understand wildness as a phenomenological and relational entity and aim to make sense of the multiple ways in which personal entanglements with particular places inform contingent and place-based ideas of wildness. Although there are many dimensions to both the experience and the idea of wildness, in this paper we reflect in particular on one: vitality. We draw our data from dozens of interviews held across Canada and base our interpretations on a combination of traditional Indigenous ecological knowledge, relational ontologies, and more-than-representational theories.
Executive Education in India: Current and Future Directions for HR Professionals
Authors: Parikh Indira J.
Published: March 2019

Executive development is imperative to organisational development and design. As organisations witness transformations in the internal and external environments, there is a need to equip executives with relevant skills, perspectives and competencies. The education provided by business schools may help to a limited extent for here and now. Rapid changes in the environment render earlier learning obsolete. Thus, a broad-based programme that encompasses skills, knowledge, perspectives and experiential components helps individuals in their organisational journeys and growth. It starts with settling in (through induction). It further proceeds to gaining a broader outlook over general and functional roles and knowledge. The trajectory further enables individuals explore leadership maps and definitions of the systems, structures and processes that they are a part of. Along with the central key functions, it has also become essential to comprehend the fact that our organisational roles interact with our social roles, mainly within the family and the larger context. This article also is an attempt to understand how management institutes, in-company training programmes and open programmes can facilitate in designing programmes to execute the same by including growth at different stages of personal, social and workspaces. From time to time, it is important to reflect, renew and take initiatives for the renewal and regeneration of the self, collectivity and the organisation.