bluuebunny/crossref_metadata_2025 huggingface dataset:
Dual RNA-Seq Analysis Reveals Transcriptome Effects during the Salmon–Louse Interaction in Fish Immunized with Three Lice Vaccines
Authors: Casuso Antonio , Valenzuela-Muñoz Valentina , Gallardo-Escárate Cristian
Published: November 2022

Due to the reduced efficacy of delousing drugs used for sea lice control in salmon aquaculture, fish vaccines have emerged as one of the most sustainable strategies in animal health. Herein, the availability of C. rogercresseyi and Salmo salar genomes increases the capability of identifying new candidate antigens for lice vaccines using RNA sequencing and computational tools. This study aimed to evaluate the effects of two recombinant antigens characterized as peritrophin and cathepsin proteins on the transcriptome profiling of Atlantic salmon during a sea lice infestation. Four experimental groups were used: Peritrophin, cathepsin, and peritrophin/cathepsin (P/C), and PBS as the control. C. rogercresseyi female, S. salar head kidney, and skin tissue samples were sampled at 25 days post-infestation (dpi) for Illumina sequencing and RNA-seq analysis. Differential gene expression, gene ontology, and chromosomal expression analyses were performed. Furthermore, the dual RNA-seq analysis approach was performed to simultaneously explore host and pathogen transcriptomes, identifying functional associations for vaccine design. The morphometry of female sea lice exposed to immunized fish was also evaluated. The RNA-Seq analysis exhibited prototype-dependent transcriptome modulation, showing a conspicuous competition for metal ions during the infestation. Moreover, Dual RNA-seq analysis revealed vaccine-dependent gene patterns in both the host and the pathogen. Notably, significant morphometric differences between lice collected from immunized and control fish were observed, where cathepsin and P/C showed 57% efficacy. This study showed the potential of two proteins as lice vaccines for the salmon industry, suggesting novel molecular mechanisms between host–parasite interactions.
A Social Cognitive Theory Approach to Understanding Parental Attitudes and Intentions to Vaccinate Children during the COVID-19 Pandemic
Authors: Zhu Ying , Beam Michael , Ming Yue , Egbert Nichole , Smith Tara C.
Published: November 2022

The distribution of the COVID-19 vaccine represents a path towards global health after a worldwide pandemic. Yet, the U.S. response to the vaccination rollout has been politically polarized. The aim of this paper is to contribute to the understanding of the contextual factors that influence parents’ attitudes towards health officials and their intention to vaccinate children, focusing on communication behaviors, personal factors, and geographic locations. We use Bandura’s triadic reciprocal determinism (TRD) model which posits reciprocal influence between personal factors, environmental factors, and behaviors. We found that personal factors (having younger children and identifying as Republican partisans), and the behavioral factor of conservative news use were significantly related to more negative attitudes towards health officials and lower vaccination intentions. Conversely, Democrats and liberal news use were significantly related to warmer attitudes and greater vaccination intentions. The environmental factor of geographic location across four states with different partisan dynamics was not significantly related to attitudes and behavioral intentions. Results from a post-hoc analysis show that news media use and partisanship were the strongest correlates of parents’ attitudes towards health officials. This evidence points to the politicization of the COVID-19 vaccine being a key consideration regarding vaccine uptake.
COVID-19 Vaccine-Associated Ocular Adverse Effects: An Overview
Authors: Ichhpujani Parul , Parmar Uday Pratap Singh , Duggal Siddharth , Kumar Suresh
Published: November 2022

Background: To address the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), vaccination efforts were initiated across the globe in December 2020 and are continuing. We report the onset interval and clinical presentations of ocular adverse effects following SARS-CoV-2 vaccination. Methods: For this narrative review, articles in the English language, published between 1 January 2020 to 1 September 2022, were included to formulate a list of the reported ocular adverse effects of different COVID-19 vaccines. Results: During this period, ocular adverse effects have been reported with BNT162b2 (Pfizer), mRNA-1273 (Moderna), AZD-1222 (AstraZeneca), and Ad26.COV2.S (Johnson & Johnson) vaccines. Endothelial graft rejection, herpes simplex virus keratitis, herpes zoster ophthalmicus, anterior uveitis, eyelid edema, purpuric rashes, ischemic optic neuropathy, and cranial nerve palsies were the most reported with BNT163b2. Retinal hemorrhages, vascular occlusions, and angle closure glaucoma were the most reported with AZD-1222. Most of the ocular adverse effects reported in the literature had a good to fair prognosis with appropriate management. Conclusions: Evidence regarding the ocular adverse effects does not outweigh the benefits of SARS-CoV-2 vaccination in patients with pre-existing systemic or ophthalmic diseases. This review provides insights into the possible temporal association between reported ocular adverse events and SARS-CoV-2 vaccines; however, further investigations are required to identify the link between potential causality and pathological mechanisms.
The Chemical Composition, Fermentation End-Product of Silage, and Aerobic Stability of Cassava Pulp Fermented with Lactobacillus casei TH14 and Additives
Authors: Pongsub Sunisa , Suntara Chanon , Khota Waroon , Boontiam Waewaree , Cherdthong Anusorn
Published: November 2022

This study evaluated the effects of cassava pulp fermented with Lactobacillus casei TH14, urea, and molasses on its chemical composition, the fermentation end-product of silage, and aerobic stability. A 2 × 2 × 2 factorial arrangement with a randomized complete block design was employed. The first factor: level of L. casei TH14 [L; 0 and 105 cfu/kg fresh matter (FM)], the second factor: level of molasses (M; 0 and 4% DM), the third factor: level of urea (U; 0 and 4% DM), and the number of days of fermentation (7, 14, and 21 days) were evaluated using a statistical block. There were interactions among CSP fermented with different additives on DM content (p < 0.05). The control group (CON) and CSP fermented with L, L×M, and L×U had lower DM contents than U, U×M, and L×U×M. The crude protein of CSP was increased by interaction of L×U and U×M additives (p < 0.05 and p < 0.01, respectively). Interaction effects between L and U and NDF content were detected (p < 0.05). The L×U combination resulted in a significantly lower NDF than the other groups. The interaction between L×U×M had no effect on the change in the CSP fermentation process (p > 0.05). The combination of U×M caused a poorer pH than other groups (p < 0.01). The ammonia-N content was higher than others, when CSP was fermented with L×U (p < 0.01) or U×M (p < 0.05), respectively. The lactic acid levels in fermented CSP were higher (p < 0.01) than in other groups through the L. casei. The interaction between L×U×M had an influence on lactic acid bacteria (LAB) (p < 0.01) and aerobic bacteria (p < 0.01). The highest LAB population (p < 0.01) at 106 cfu/g FM was found in CSP fermented with L. casei and molasses. In conclusion, the current study shows that CSP treated with L×U×M resulted in good preservation by recovering DM, a low number of aerobic bacteria, and greater LAB than other treatments, with the exception of the L×U×M addition. A 21-day fermentation period is advised because it produces products with greater levels of crude protein, lactic acid, acetic acid, and propionic acid.
A Review of Radiomics and Artificial Intelligence and Their Application in Veterinary Diagnostic Imaging
Authors: Bouhali Othmane , Bensmail Halima , Sheharyar Ali , David Florent , Johnson Jessica P.
Published: November 2022

Great advances have been made in human health care in the application of radiomics and artificial intelligence (AI) in a variety of areas, ranging from hospital management and virtual assistants to remote patient monitoring and medical diagnostics and imaging. To improve accuracy and reproducibility, there has been a recent move to integrate radiomics and AI as tools to assist clinical decision making and to incorporate it into routine clinical workflows and diagnosis. Although lagging behind human medicine, the use of radiomics and AI in veterinary diagnostic imaging is becoming more frequent with an increasing number of reported applications. The goal of this paper is to provide an overview of current radiomic and AI applications in veterinary diagnostic imaging.
Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways
Authors: Peng Jin , He Qi , Li Shuaichen , Liu Tao , Zhang Jiantao
Published: November 2022

Long-term exposure to low-dose lipopolysaccharide can impair intestinal barriers, causing intestinal inflammation and leading to systemic inflammation. Hydrogen-rich water possesses antioxidant and anti-inflammatory functions and exerts inhibitory effects on various inflammatory diseases. In this study, we investigated whether oral hydrogen-rich water could prevent lipopolysaccharide-induced chronic intestinal inflammation. An experimental model was established by feeding hydrogen-rich water, followed by the injection of lipopolysaccharide (200 μg/kg) in the tail vein of rats after seven months. ELISA, Western blot, immunohistochemistry, and other methods were used to detect related cytokines, proteins related to the NF-κB and Nrf-2 signaling pathways, and tight-junction proteins to study the anti-inflammatory and antioxidant effects of hydrogen-rich water. The obtained results show that hydrogen-rich water significantly increased the levels of superoxide dismutase and structural proteins; activated the Nrf-2 signaling pathway; downregulated the expression of inflammatory factors cyclooxygenase-2, myeloperoxidase, and ROS; and decreased the activation of the NF-κB signaling pathway. These results suggest that hydrogen-rich water could protect against chronic intestinal inflammation in rats caused by lipopolysaccharide-induced activation of the NF-κB signaling pathway by regulating the Nrf-2 signaling pathway.
Virtualization of Modern Finance and Its Consequences for Human Society
Authors:   Lomonosov Moscow State University., Sazhina Muza A.
Published: November 2022

The article dwells on the content of the modern finance virtualization, replacement of the real financial sphere with images, titles, simulations with their special space, time, laws and values. Objective reasons for this process are noted: monetary origins of virtualization, equity ownership and issue of securities, derivatives as financial innovations, widespread introduction of modern means of communication and information. Special role of subjective factor in increasing the finance virtualization, when speculation is used to inflate the money supply, is shown. It is emphasized that modern finance has transformed from providing and servicing the economy into dominating the economy. Working primarily for themselves, they operate globally and are constantly in movement. They are characterized by a permanent change of ownership, blurring, diffusion of property rights, loss of control and exclusion from market self-regulation. Virtual finance is strengthening its dominance, sucking the lifeblood from material wealth, nature, man, appropriating the creative potential of society. At the same time, phenomenon of financial property and power is hidden, veiled, fictitious, dispersed throughout the world space. The paper concludes that it is necessary to reduce, to put under democratic control the growing volume of modern virtual finance both at the national and international levels, and channel it to address the socio-economic problems of society. But it cannot be limited to this. The threat to existence of the modern world civilization has necessitated preservation and protection of the basic values of human society, the main of which is the person himself with his knowledge, culture, ethics and morality. He must be a healthy, developing personality, provided with all necessary benefits. Man is at the center of society and the state, society and the state should take care of the person.
Fisheries and Aquaculture Development in West Africa: an Opportunity for Russia?
Authors:   Centre for Global and Strategic Studies of the Institute for African Studies of the Russian Academy of Sciences, Sugakov Gleb K.
Published: November 2022

The Gulf of Guinea is one of the most productive fishing areas in the ocean, which has attracted the attention of many external actors. The article considers the feasibility of cooperation between Russia and the member countries of the Fisheries Committee for the West Central Gulf of Guinea (FCWC) in the field of fisheries and aquaculture, as today Russian companies operate mainly to the north, in the waters of Morocco and Mauritania. The results of the analysis of the FCWC 2021-2030 Strategic Action Plan reveal the directions of maritime activities in the countries, the nature of external donors’ participation in the implementation of the project and the possibility of Russia’s inclusion. A conclusion is made about the prospects of russian investments in the development of fisheries and aquaculture in the region.
Investment Attractiveness of the Russian Energy Sector for Foreign Investors: Assessment and Recommendations
Authors:   Lomonosov Moscow State University, Tszilu Van
Published: November 2022

The article analyses the investment attractiveness of the Russian energy sector for foreign investors. Analysis is based on such indicators as the volume of energy resources’ production and export as well as their dynamics, foreign direct investment in the country's energy industry, portfolio investment in the "green" energy industry. The author draws up a conclusion that despite the exports decrease in the main types of energy resources (oil, gas, coal, energy) over the past few years (2020–2021), Russia continues to play a leading role in the global fuel and energy complex, the volume of foreign direct investment in industry is steadily growing, the “green” energy industry is actively developing. The author also dwells on the difficulties that foreign investors have to face when investing in the Russian energy sector. The present study results in identifying the main directions for improving investment attractiveness of the Russian energy sector for potential foreign investors.
Implied (Implicit) Limitations on Corporate Governance
Authors:   The Corporate and Project Management Institute (Moscow), Lutsenko Sergej I. ,   Institute for Economic Strategies,   Contours of the Concept of Developing Financial Cluster of the Russian Federation in the Long-Term Period Project
Published: November 2022

The author examines the compliance of the legal nature of the company with the principle of social justice. The shareholder has priority in corporate governance by virtue of the economic and legal status. The interests of a participant (shareholder) are derived from the interests of a commercial organization. The goals of the company must take into account the interests of other stakeholders in modern conditions. The author proposes a tool of “implied limitations” which allows to include an element of social justice in managerial discretion.
On Sanctions and the Exchange Rate
Authors:   Financial University under the Government of the Russian Federation, Ershov Mikhail V. , Tanasova Anna S. ,   Financial University under the Government of the Russian Federation
Published: November 2022

The article emphasizes that freezing of Russian gold and foreign exchange reserves was previously accurately predicted by Russian experts. Attention is drawn to the fact that weakening of the ruble was one of the goals of the sanctions impact on the Russian economy that Western countries were bearing in mind. It is obvious that the exact opposite — preventing its depreciation and turning the ruble into a stable strong currency — is an anti-sanction measure. With high dependence of the Russian economy on imports, as well as in the situation when it is necessary to find alternative ways for imports (primarily for investment), which will lead to their higher prices with corresponding consequences, an excessive exchange rate depreciation may adversely affect economic development, especially in a long term. In addition, extremely important is ensuring stability of the exchange rate. It is concluded that stable and non-depreciating ruble will form the basis for consistent development of business and expand the possibilities for using the ruble in foreign trade settlements as well. It is particularly relevant in the context of restrictions on the use of leading currencies in foreign trade.
Endoscopic application of incomplete silver salt of poly (acrylic acid) in patients with pulmonary hemorrhage
Authors:   FSBEI CPE Russian Medical Academy of Continuous Professional Education, Chernekhovskaya N. E. , Korzheva I. Yu. ,   City Clinical Hospital named after S. P. Botkin, Andreev D. V. ,   D. D. Pletnev City Clinical Hospital, Povalyaev А. V. ,   FSBEI CPE Russian Medical Academy of Continuous Professional Education, Tereshchenko S. G. ,   SBHI Moscow Regional Clinical Research Institute named after M. F. Vladimirsky
Published: November 2022

Pulmonary hemorrhage is a severe complication associated with high lethality. One of the main methods of diagnosis and treatment is the endoscopic one. This paper describes the experience of treating 100 patients with pulmonary hemorrhage. Incomplete silver salt of poly (acrylic acid) (ISPA), a new generation biologically active hemostatic with silver nanoparticles, was used as a hemostatic agent, which was injected into the tracheobronchial tree during bronchoscopy in the amount of 3.0 to 10.0 mL depending on the degree of pulmonary hemorrhage. In all patients, hemostasis was achieved within a time interval of 30 seconds to 1 minute with a single injection of the ISPA solution. No complications or bleeding recurrence were registered.
The drugs Toxi-sorb and Lecithin in the rations of steers on fattening and the effectiveness of their use
Authors:   Federal State Budgetary Educational Institution of Higher Education “Gorsky State Agrarian University”, Russia, Republic of North Ossetia-Alania, Vladikavkaz, Shabanov M. O. , Temiraev R. B. ,   Federal State Budgetary Educational Institution of Higher Education “Gorsky State Agrarian University”, Russia, Republic of North Ossetia-Alania, Vladikavkaz
Published: November 2022

The industrial technology of steers for meat fattening implies an increase in the proportion of local feed products in the ration of fattened animals to reduce the prime-cost of meat products. However, there is a problem of compliance with the ecological purity of the beef produced. After all, in the presence of environmental pollution factors with various toxins of chemical origin, there is a risk of their ingestion with feed, which is associated with contamination of meat products produced by them. The purpose of the research was to study the drugs Toxi-sorb and Lecithin in the rations of fattened steers and the eff ectiveness of their use. Under the conditions of the south of Russia the expediency of using joint additives in the rations of fattened steers of the adsorbent Toxi-sorb and phospholipid Lecithin for detoxifi cation of heavy metals in order to intensify metabolic processes, increase beef productivity, consumer qualities of beef was justifi ed. It was found as a result of research that in order to increase beef productivity, consumer qualities of beef and the profi tability of its production (in the presence of excessive amounts of heavy metal salts in feed) the adsorbent Toxi-sorb in the dose of 1,25 kg/t of compound feed and Lecithin in the dose of 10 g/100 kg of live weight should be included in the rations of fattening steers. During the production trial the fattened steers of the experimental group surpassed the steers of the control group in absolute and average daily live weight gains by 10,11 %. Taking into account the higher growth–stimulating eff ect of the joint additives of the tested drugs the best feed to product conversion rate was for the steers of the experimental group, which did intake by 9,78 % less EFU and by 9,86 % less digestible protein to obtain 1 kg of gain than the control steers.
Cuadro de mando integral aplicado en la Corporación Nacional de Electricidad, Provincia de Manabí. 2021
Authors: Loor Mendoza Cristhian Jonathan , Bravo Giler María Amelia
Published: November 2022

El Balanced Scorecard, o Cuadro de Mando Integral representa una de las más destacadas herramientas de gestión aplicadas en las organizaciones modernas, en el que se compendia gran cantidad de indicadores y acciones que se convierten en soportes del sistema de gestión empresarial. Vinculado a lo precedente, se plantea el objetivo general de aplicar el Cuadro de Mando Integral a la Unidad de Negocios de la Corporación Nacional de Electricidad, para optimizar los servicios y la rentabilidad de la organización. La metodología de estudio correspondió al no experimental, exploratorio con alcance descriptivo y enfoque cualitativo, se aplicó el modelo de Bastidas y Feliu, empleado en organizaciones del sector público. Entre las principales conclusiones están que la implementación del Cuadro de Mando Integral en la unidad de negocios de la Empresa Eléctrica Pública Estratégica Corporación Nacional de Electricidad , produjo la necesidad de priorizar el aprovechamiento del potencial que tiene el talento humano, de la expansión tecnológica, y de la atención personalizada al usuario, con un servicio que contenga calidad, calidez, y eficiencia, aprovechando todos los componentes como factores claves para alcanzar los objetivos planteados. Poner atención a la gestión por procesos con el fin de alinearlos con la misión de la empresa, a la ejecución de métodos Project Management Body of Knowledge, para dar seguimiento a los avances de la empresa. Lo anterior aportará con la toma de decisiones para alcanzar metas y objetivos a corto, mediano y largo plazo.
Perfil de linguagem de usuários de um Serviço de Fisioterapia Neurofuncional
Authors: Cerqueira Alves Beatriz , Satler Corina Elizabeth , Breder Virgília , De Freitas Silva Jéssika , Luchesi Cera Maysa
Published: November 2022

Introdução. A afasia pode se manifestar após Acidente Vascular Cerebral (AVC) e está associada a piores recuperações funcionais e cognitivas. Objetivo. Caracterizar o perfil de linguagem de usuários de um serviço de Fisioterapia Neurofuncional que sofreram AVC. Método. Participaram do estudo 15 pacientes adultos (10 homens), usuários do Ambulatório de Fisioterapia Neurofuncional do Hospital Universitário de Brasília que apresentavam histórico de AVC. Todos realizaram o rastreio de linguagem, que envolveu avaliação da compreensão oral, repetição, nomeação, narrativa e fluência fonológica. Resultados. As habilidades de compreensão oral, repetição, nomeação oral, narrativa e fluência fonológica estiveram alteradas, respectivamente, em 20%, 20%, 13%, 87% e 67% nos pacientes estudados. Foram identificados nove casos de afasia subcortical, quatro de afasia discursiva e apenas dois pacientes apresentaram desempenho de linguagem adequado. Nenhum dos pacientes havia sido encaminhado para fonoterapia. Conclusão. A alteração no perfil da linguagem de usuários de um serviço de Fisioterapia em reabilitação motora após AVC evidencia a necessidade de identificação das manifestações das afasias por parte dos profissionais de saúde, o que proporcionará melhores condições para a reabilitação e recuperação clínica.
Notre-Dame de Sheshan à Shanghai, basilique de pèlerinage des Jésuites français en Chine, 1867-1935
Authors: Coomans Thomas
Published: November 2022

À 35 km au sud-ouest de Shanghai, une colline d’une centaine de mètres de hauteur se dresse au milieu de la grande plaine du delta du Yang-Tseu-Kiang. La colline de Sheshan (Zô-cè en Shanghaïen), lieu entre ciel et terre, attira des moines bouddhistes depuis le XIe siècle. Les Jésuites français, dont Shanghai était le fleuron de leur mission en Chine, prirent possession de la colline en 1863 et y développèrent un pèlerinage marial. L’article retrace comment, en un demi-siècle, un pèlerinage local devint le plus grand sanctuaire marial de Chine : à la chapelle érigée au sommet de la colline en 1867 se substitua dès 1871-1873 une église de style néoclassique, elle-même remplacée par la grande basilique actuelle érigée de 1924 à 1935 d’après les plans du père Alphonse De Moerloose, architecte-missionnaire néogothique belge. Chaque étape est placée dans son contexte historique local, national – Shanghai étant le centre de l’église catholique en Chine dans les années 1860-1950 – et international. L’article s’interroge aussi sur la perception de ce sanctuaire chrétien occidental par les Chinois. Pourquoi les Jésuites optèrent-ils dans les années 1920 pour un style architectural européen, au moment où le Saint-Siège lançait sa nouvelle politique d’inculturation au synode de Shanghai et promouvait un style architectural «sino-chrétien » ?
Intraoperative Urine Oxygen in Cardiac Surgery and 12-Month Outcomes
Authors: Parry Samuel R. , Silverton Natalie A. , Hall Isaac E. , Stoddard Gregory J. , Lofgren Lars , Kuck Kai
Published: November 2022

Key Points

Low intraoperative urinary oxygen during cardiac surgery is associated with increased risk of poor 12-month outcomes.

With decreasing urinary oxygen thresholds, the risk of poor 12-month outcomes increases.
A Machine Learning Model to Predict Diuretic Resistance
Authors: Mercier Joey A. , Ferguson Thomas W. , Tangri Navdeep
Published: November 2022

Key Points

Our machine learning algorithm was able to quickly predict those at risk for diuretic resistance using common variables.

Our machine learning algorithm could easily be implemented within electrical medical software (or as an online calculator).

Our study provides a proof of concept/framework for the development of future machine learning models.

Background

Volume overload is a common complication encountered in hospitalized patients, and the mainstay of therapy is diuresis. Unfortunately, the diuretic response in some individuals is inadequate despite a typical dose of loop diuretics, a phenomenon called diuretic resistance. An accurate prediction model that predicts diuretic resistance using predosing variables could inform the right diuretic dose for a prospective patient.

Methods

Two large, deidentified, publicly available, and independent intensive care unit (ICU) databases from the United States were used—the Medical Information Mart for Intensive Care III (MIMIC) and the Philips eICU databases. Loop diuretic resistance was defined as <1400 ml of urine per 40 mg of diuretic dose in 24 hours. Using 24-hour windows throughout admission, commonly accessible variables were obtained and incorporated into the model. Data imputation was performed using a highly accurate machine learning method. Using XGBoost, several models were created using train and test datasets from the eICU database. These were then combined into an ensemble model optimized for increased specificity and then externally validated on the MIMIC database.

Results

The final ensemble model was composed of four separate models, each using 21 commonly available variables. The ensemble model outperformed individual models during validation. Higher serum creatinine, lower systolic blood pressure, lower serum chloride, higher age, and female sex were the most important predictors of diuretic resistance (in that order). The specificity of the model on external validation was 92%, yielding a positive likelihood ratio of 3.46 while maintaining overall discrimination (C-statistic 0.69).

Conclusions

A diuretic resistance prediction model was created using machine learning and was externally validated in ICU populations. The model is easy to use, would provide actionable information at the bedside, and would be ready for implementation in existing electronic medical records. This study also provides a framework for the development of future machine learning models.
ANALISIS BURNOUT DAN WORK LIFE BALANCE TERHADAP TURNOVER INTENTION DI MASA PANDEMI COVID-19
Authors: Exacta Egivzi Arya , Komariah Kokom , Saori Sopyan
Published: November 2022

Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh burnout dan work life balance terhadap turnover intention. Metode yang dipakai dalam penelitian ini yaitu metode deskriptif dan asosiatif dengan cara kuantitatif. Teknik pengambilam sampel didalam penelitian ini memakai Teknik sampling jenuh, sampel yang dipilih dalam penelitian ini yaitu sebanyak 63 orang karyawan Sparks Forest Adventure. Teknik analisis data yang dipakai dalam penelitian ini yaitu teknik analisis korelasi ganda, analisis koefisien determinasi, analisis regresi linear berganda, uji signifikan parsial (uji-T) dan uji signifikan simultan (Uji-F). Berdasarkan hasil dari uji koefisien korelasi ganda didapatkan nilai R sebesar 0,743 artinya bahwa ada hubungan yang kuat antara burnout dan work life balance terhadap turnover intention di Sparks Forest Adventure. Hasil uji koefisien determinasi didapatkan dari perolehan nilai (R Square) yaitu sebesar 0,553 artinya hubungan antara burnout dan work life balance terhadap turnover intention di Sparks Forest Adventure terdapat hubungan sebesar 55,3% dan 44,7% dipengaruhi variabel lain. Berdasarkan hasil analisis maka dapat disimpulkan bahwa Burnout dan Work Life Balance berpengaruh signifikan terhadap Turnover Intention pada sparks forest adventure sukabumi.
FAKTOR-FAKTOR YANG MEMPENGARUHI PROFITABILITAS PERBANKAN YANG LISTING DI BEI PERIODE 2016-2020
Authors: Nata Liyas Jeli , Rahim Rida
Published: November 2022

Penelitian ini bertujuan untuk menganalisis pengaruh Capital Adequacy Ratio(CAR), Loan to Deposit Ratio (LDR), Net Interest Margin (NIM), Biaya Operasional terhadap Pendapatan Operasional (BOPO) dan , Non Performing Loan (NPL)terhadap Profitabilitas Perbankan (ROA). Populasi yang menjadi obyek dalam penelitian ini adalah bank umum go public yang terdaftar di Bursa Efek Indonesia periode tahun 2016-2020. Jumlah sample yang digunakan adalah 25 bank umum go public yang terdaftar di Bursa Efek Indonesia. Sampel penelitian diambil secara purposive sampling dengan kriteria tertentu yaitu perusahaan perbankan yang tergolong dalam bank umum go public dan makmimal pada awal tahun 2013 telah terdaftar di Bursa Efek Indonesia, serta bank yang telah mempublikasikan laporan keuangannya pada tahun 2013-2017. Metode yang digunakan dalam penelitian ini adalah dengan menggunakan analisis regresi berganda dengan uji hipotesis yaitu uji t dan uji F. Sebelum menggunakan analisis regresi berganda, dilakukan uji asumsi klasik terlebih dahulu. Berdasarkan hasil uji hipotesis secara parsial (uji t) pada bank umum go public menunjukkan bahwa variabel CAR, NPL, BOPO, NIM, dan berpengaruh signifikan terhadap profitabilitas perbankan. Sedangkan variabel BOPO tidak signifikan terhadap profitabilitas perbankan. Nilai adjusted R2 dalam model regresi bank go public diperoleh sebesar 0,328. Hal ini menunjukkan bahwa besar pengaruh variabel independent yaitu CAR, LDR, NIM, BOPO dan NPL terhadap variabel dependent (ROA) sebesar 32,8% sedangkan sisanya sebesar 67,2% dipengaruhi oleh faktor lain. Selain itu nilai R2 adalah 0,328. Jika nilai R2 semakin mendekati 1 maka variabel- variabel bebas (CAR, NPL, BOPO, LDR, NIM, dan Pangsa Kredit) semakin kuat pengaruhnya dalam menjelaskan variabel terikat (ROA).
FINANCIAL DISTRESS MENGGUNAKAN METODE GROVER, FOSTER, SPRINGATE DAN ALTMAN (Z-SCORE)
Authors: Irman Mimelientesa , Halim Adi Gusman , Wati Yenny , Okalesa Okalesa , Andi Andi
Published: November 2022

Tujuan penelitian ini adalah untuk mengetahui bagaimana Model Grover, Model Foster, Model Springate, dan Model Altman Z-Score menganalisis Financial Distress pada perusahaan Consumer Goods yang terdaftar di Bursa Efek Indonesia. Periode yang digunakan dalam penelitian ini adalah lima tahun yaitu mulai tahun 2016-2020.Penelitian ini menggunakan pendekatan deskriptif kuantitatif yaitu penelitian yang digunakan untuk mengetahui nilai dari suatu variabel. Model analisis data yang digunakan adalah Model Grover, Model Foster, Model Springate, dan Model Altman Z-Score. Penelitian ini dilakukan dengan mengambil data sekunder dengan kriteria yang telah ditentukan dari situs resmi Bursa Efek Indonesia.
ANALISIS PENGARUH TINGKAT KESEHATAN BANK DENGAN METODE RGEC TERHADAP KINERJA KEUANGAN (ROA) SEKTOR PERBANKAN KONVENSIONAL YANG TERDAFTAR DI BEI TAHUN 2015-2020
Authors: Wulansari Jessy , Chandra Stefani
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh tingkat Kesehatan bank terhadap terhadap kinerja keuangan ROA pada bank yang terdaftar di Bursa Efek Indonesia periode 2015-2020 dengan Metode RGEC (Risk Profile, Good Corporate Governance, Earnings, dan Capital) dimana dalam penelitian, Rasio Risk Profile diproksikan dengan NPL (Non Performing Loan) dan LDR (Loan to Deposit Ratio), Good Corporate Governance dengan Rasio GCG, Earnings diproksikan dengan NIM (Net Interest Margin), dan BOPO (Beban Operasional terhadap Pendapatan Operasional), serta Capital yang diproksikan rasio CAR (Capital Adequacy Ratio). Objek penelitian ini adalah perusahan sektor perbankan yang terdaftar di BEI periode tahun 2015 sampai dengan 2020. Populasi dalam penelitian ini adalah 45 perusahaan. Teknik pengambilan sampel dalam penelitian ini menggunakan metode purposive sampling dan sampel yang diperoleh sebanyak 38 perusahaan. Teknik analisis data yang digunakan adalah analisis regresi linear berganda dengan menggunakan SmartPls 3.0 yang dikarenakan data penelitian tidak berdistribusi dengan normal. Hasil dari penelitian ini menunjukkan bahwa variabel NPL dan LDR tidak memiliki pengaruh terhadap ROA; variabel NIM, BOPO, dan CAR memiliki pengaruh positif signifikan terhadap ROA pada sektor perbankan konvensional yang terdaftar di BEI tahun 2015-2020.
ANALISIS FAKTOR-FAKTOR YANG MEMENGARUHI NIAT PEGAWAI UNTUK MELAKUKAN WHISTLEBLOWING (STUDI PADA PT. TIRTA EMAS KEMASINDO)
Authors: Chandra Jennifer , Indrastuti Sri , Fayola Wilona
Published: November 2022

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh personal cost of reporting, komitmen organisasi, dan tingkat keseriusan kecurangan terhadap niat pegawai PT. Tirta Emas Kemasindo untuk melakukan whistleblowing. Populasi dalam penelitian ini adalah karyawan tetap di PT. Tirta Emas Kemasindo, yang berjumlah 73 orang. Pengambilan sampel dalam penelitian ini dilakukan dengan menggunakan teknik purposive sampling, dimana sampel dalam penelitian ini adalah karyawan tetap yang tidak menjabat di struktural, yang berjumlah 53 orang. Metode analisis dilakukan dengan analisis regresi berganda dengan menggunakan program SPSS versi 16. Berdasarkan hasil pengujian hipotesis dengan uji t dapat disimpulkan bahwa H2 dan H3 diterima, yang berarti komitmen organisasi dan tingkat keseriusan kecurangan berpengaruh positif signifikan terhadap niat pegawai PT. Tirta Emas Kemaisndo untuk melakukan whistleblowing. Hasil pengujian hipotesis dengan uji t juga menyimpulkan bahwa H1 ditolak, yang berarti personal cost of reporting tidak berpengaruh negatif signifikan terhadap niat pegawai PT. Tirta Emas Kemasindo untuk melakukan whistleblowing.
Hubungan Kekerabatan Bahasa Pakpak dan Alas: Kajian Linguistik Historis Komparatif
Authors: Sinaga Lara Desma , Widyawati Dwi
Published: November 2022

Languages that are in one proto are thought to still have language kinship. This study will describe how the kinship of the Pakpak and Alas languages and find out the time of separation and the age of the Pakpak and Alas languages. The methods used are qualitative and quantitative methods. From the results of the study, it was found that the Pakpak and Alas languages have a kinship relationship in the family class because they are in the range of 44%. This indicates that the Pakpak and Alas languages are in the same proto and have family relationships. Pakpak and Alas languages are considered to be the same language around 1891 thousands of years ago. In addition, the Pakpak and Alas languages are thought to have started to separate from a single proto-language around the year 131 ADKeywords: Alas language; kinship; Pakpak language; comparativeAbstrakBahasa yang berada pada satu proto diduga masih memiliki kekerabatan Bahasa.  Penelitian ini akan menggambarkan bagaimanakah hubungan kekerabatan bahasa Pakpak dan Alas serta mengetahui waktu pisah dan usia  bahasa Pakpak dan Alas. Metode yang digunakan adalah metode kualitatif dan kuantitatif. Dari hasil penelitian didapati bahwa bahasa Pakpak dan bahasa Alas memiliki hubungan kekerabatan pada kelas family karena berada pada kisaran 44% Ini menunjukkan bahwa bahasa Pakpak dan Alas berada pada satu proto yang sama dan memiliki hubungan family(keluarga). Bahasa Pakpak dan Alas diperhitungkan merupakan satu bahasa yang sama sekitar 1891 ribuan tahun yang lalu. Selain itu, bahasa Pakpak dan Alas diperkirakan mulai berpisah dari satu bahasa proto kira lira tahun 131MasehiKata Kunci : bahasa Pakpak; bahasa Alas; kekerabatan; komparatif
EFECTO DEL ETHREL SOBRE EL ACAME, EL RENDIMIENTO Y SUS COMPONENTES EN LAS VARIEDADES DE MAÍZ V-18 Y H-139
Authors: Arellano-Vázquez Jose Luis , Salinas-Moreno Yolanda , Mendoza-Zamora Agustín
Published: November 2022

El objetivo de este estudio fue conocer los efectos de la concentración y época de aplicación del ácido 2-cloroetil fosfónico (ethrel) sobre el grado de acame, el rendimiento y sus componentes, la longitud del tallo, el área foliar de la hoja de la mazorca principal y el peso seco de la planta en las variedades de maíz (Zea mays L.) V-18 y H-139. El ethrel se aplicó a las dosis de 0, 140 y 280 g ha-1 de ingrediente activo en las etapas de diferenciación de la espiga y diferenciación de la mazorca principal. Se utilizó el arreglo de tratamientos de parcelas subdivididas bajo el diseño experimental de bloques completos al azar con tres repeticiones. El experimento se estableció en terrenos del campo experimental Santa Lucía Coatlinchán, Edo. de México, México. La concentración de 280 gha-1 de ethrel redujo el área foliar de la hoja de la mazorca principal al momento de la antesis en 13 %, el pesos seco total de la planta en antesis en 15 %, la longitud de los entrenudos del tercio inferior del tallo en 3.4 cm, la altura de planta en 28 cm, el acame de las variedades en 25 %, redujo también, el período a la madurez fisiológica en 12 días y el rendimiento de grano por hectárea en 13 %, debido principalmente a la reducción en los componentes número de granos y peso de grano por metro cuadrado. La aplicación de ethrel en la etapa diferenciación de la mazorca redujo en mayor magnitud el acame y el área foliar de la hoja de la mazorca. El híbrido H-139 presentó mayor rendimiento y resistencia al acame. En ambas variedades se observó una correlación negativa entre la concentración de ethrel aplicado y el grado de acame, (r=-0.48* en V-18 y r=- 0.57** en H-139), también se observó una correlación positiva entre el acame y el área foliar de la hoja de la mazorca (r=0.75** en V-18 y r=0.76** en H-139), y entre el acame y el peso seco total de planta a la cosecha (r=0.52** en V-18 y r=0.66** en H-139).
ESTIMACIÓN DE VARIANZA ADITIVA Y HEREDABILIDAD EN DOS POBLACIONES DE TOMATE DE CÁSCARA (Physalis ixocarpa Brot.)
Authors: Pérez-Grajales Mario , Sahagún-Castellano Jaime , Peña-Lomelí Aureliano , Alvarado-Navarro Francisco , Aguilar-Gudino Armando
Published: November 2022

El objetivo del presente trabajo fue estudiar el cambio en la varianza aditiva y la heredabilidad de los caracteres peso y número de frutos después de seis ciclos en selección de la variedad “Rendidora” de tomate de cáscara (Physalis ixocarpa Brot.). Para realizar lasestimaciones se empleó la metodología de medios hermanos maternos recientemente propuesta. Después de seis ciclos de selección, la media de rendimiento mostró un cambio estadístico significativo promedio de 300 g/planta con una ganancia por ciclo de 9.08 %. Este cambio en la media poblacional debe estar asociado con un cambio en la frecuencia de los genes deseables toda vez que la estimación del coeficiente de varianza aditiva del material mejorado (SBI200-93) que fue de 17.42 % para peso de frutos y de 16.43 % para número de frutos, fue menor que el de la población original Rendidora con 37.05 y 42.66 % para peso y número de frutos, respectivamente. Esta situación general es compatible con un modelo de acción génica aditiva y una frecuencia génica de al menos 0.5; aunque otros modelos pudieran ser compatibles también. Para peso y número de frutos las estimaciones de heredabilidad en sentido estrecho con base en una media fueron 0.65 y 0.51, respectivamente, en Rendidora y 0.23 y 0.26 en SBI200-93. La superioridad de las estimaciones obtenidas en Rendidora con relación a las correspondientes obtenidas en SBI200-93 es consistente con lo observado en las varianzas aditivas.
FERTILIZACIÓN PARA LA ÓPTIMA ADAPTACIÓN Y VIGOR DE PLÁNTULAS DE TOMATE (Lycopersicon esculentum Mill.) OBTENIDOS IN VITRO
Authors: Enríquez-del Valle José Raymundo , Carrillo-Castañeda Guillermo , Sánchez-García Prometeo , Rodríguez-Mendoza María de las Nieves , Mendoza-Castillo María del Carmen
Published: November 2022

Para la producción comercial de tomate (Lycopersicon esculentum Mill.) es conocido que al fertilizar adecuadamente las plántulas se mejora, además de su establecimiento y posterior desarrollo en campo, la calidad y el rendimiento. El uso de vitroplántulas (plántulas obtenidos in vitro) en sistemas de producción de tomate, producidos en medios de cultivo y con alta humedad relativa, implica la adaptación simultánea a nuevas condiciones de nutrición, fotoperíodo natural y ambientes más secos; de esto depende el éxito del establecimiento del transplante. En este trabajo se estudió el efecto de la fertilización de vitroplántulas de Licopersicon esculentum Mill. Var. Daniela en su desarrollo. Las vitroplántulas obtenidas mediante organogénesis en tejidos foliares, cuando tuvieron aproximadamente 3 cm de longitud de tallo fueron transferidas a macetas con una mezcla 1:1 perlita-suelo. Desde eltrasplante y durante 25 días de aclimatación en el invernadero, éstas fueron irrigadas con la solución nutritiva de Steiner (1984) ajustada a los potenciales osmóticos: A) 0, B) -0.018, C) - 0.036, D) -0.054 y E)-0.072 MPa. Al final del periodo de adaptación, todas las plántulas sobrevivieron, aún las irrigadas sin fertilizante (condición A); pero, las plántulas fertilizadas con la solución C alcanzaron 25 % más longitud de tallo; con las soluciones D y E se incrementó 7 % el diámetro del tallo. Con la solución E aumentó 175 % el área foliar y 66 % la biomasa de la parte aérea, 53 % la biomasa total y 14 % el contenido de clorofila en hojas; las plántulas irrigadas con las soluciones B, C y D acumularon 36, 45 y 36 % más azúcares solubles totales, respectivamente, en comparación con las no fertilizadas.
CRUZAMIENTO INTRAESPECÍFICO EN EL CEMPOALXOCHITL (Tagetes erecta L.)
Authors: Serrato-Cruz Miguel Ángel , Miranda-Colín Salvador , Castillo-González Fernando , García-Velázquez Armando
Published: November 2022

Para conocer el cruzamiento intraespecífico y su posible implicación en la domesticación del Cempoalxochitl (Tagetes erecta L.), se realizó manualmente la autopolinización y la polinización cruzada intrapoblacional (PaP) en T. erecta cultivada y su pariente silvestre. La autopolinización en el silvestre produjo poca semilla (17 %), mientras que en el cultivado fue mayor (74 %); con la polinización PaP, hubo alta producción de semillas en ambas poblaciones (91 a 95 %). En el silvestre, las semillas de polinización PaP germinaron poco (0-4 %), pero las de autopolinización germinaron más (19-31 %); en el cultivado, la germinación fue mayor (93- 96 % de autopolinización y 100 % de PaP) que en el silvestre. Plantas silvestres obtenidas por cruzamiento PaP presentaron morfología floral normal, pero las obtenidas por autopolinización presentaron morfología floral cercana a la del cultivado, con incrementos hasta del 100 % respecto del fenotipo normal; en plantas cultivadas hubo mayor expresión floral, resultando mejor en plantas de polinización PaP que de autopolinización. Plantas silvestres derivadas de polinización PaP formaron pocas semillas (6 %), pero las de autopolinización formaron más (24 %); en las cultivadas, las plantas originadas de polinización PaP formaron 32 % de semillas, lo cual fue menor que en aquellas de autopolinización (62 %). Las respuestas que mostró la progenie silvestre obtenida por autopolinización, con tendencia parecida a las respuestas del cultivado, permiten plantear que la autopolinización en la población silvestre, produjo progenies con modificaciones seleccionadas durante el proceso de domesticación de T. erecta.
EFECTO DE MODIFICACIONES AL AMBIENTE EN LA FLORACIÓN Y FRUCTIFICACIÓN DE JITOMATE (Lycopersicon esculentum)
Authors: Ponce-Ocampo Jaime , Sánchez-Del Castillo Felipe , Contreras-Magaña Efraín , Corona-Sáez Tomás
Published: November 2022

Se realizó un experimento bajo invernadero de vidrio en donde se manejaron plántulas de jitomate (Lycopersicon esculentum, Mill) cultivar “Solarset”, para evaluar el efecto de tratamientos de baja temperatura nocturna (10 oC) durante 10 días, luz suplementaria (75 µmol.m-2.s-1 con luz fluorescente o 90 µmol.m-2.s-1 con luz fluorescente más incandescente) cinco horas por noche durante 10 días, y poda de la quinta hoja, aplicados a plántulas en semillero durante el periodo de iniciación de la primera inflorescencia, sobre el número de flores por inflorescencia (NFI), el porcentaje de plantas con la primera inflorescencia ramificada (PIR), el rendimiento y sus componentes primarios. Se utilizó un diseño de parcelas subdivididas en bloques al azar con cuatro repeticiones. No hubo diferencias significativas entre tratamientos para las variables estudiadas; sin embargo, se registró un alto NFI (6.75) y un alto porcentaje de PIR (30 %) en comparación con otros trabajos similares, indicando que las condiciones del semillero fueron muy favorables para la iniciación de la inflorescencia (incluso para el tratamiento testigo). Las hojas de plantas tratadas con luz suplementaria, realizaron fotosíntesis adicional a la del día que compensó las pérdidas de CO2 por su respiración durante la noche; sin embargo, la tasa de fotosíntesis durante el día presentó una tendencia a ser mayor en las hojas de las plantas sin luz suplementaria durante la noche, de tal manera que la cantidad neta de fotoasimilados producidos por día resultó similar a la de los tratamientos de luz suplementaria.