bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of Comfortable Nursing in the Preparation of Colostomy of Organs by Oral Magnesium Sulfate
Authors: Shu Zhou
Published: July 2021

Objective: To explore the application of comfortable nursing inÂ the preparation of colonoscopy in oral magnesium sulfate, and toÂ provide scientific reference direction for nursing staff. Methods:Â 68 patients with colonoscopy were randomly divided intoÂ experimental group and control group (n = 34). In the controlÂ group, the routine nursing intervention was used, and theÂ intervention group was treated with comfortable nursingÂ intervention. Data analysis was performed using SPSS 20.0.Â Results:Â The total satisfaction score of the experimental group wasÂ (96.88 Â± 1.26), the total satisfaction score of the control group wasÂ (80.65 Â± 3.32), the test group (P < 0.05). The incidence of adverseÂ reactions in the experimental group was significantly lower thanÂ that in the control group. The incidence of adverse reactions wasÂ 5.88% in the experimental group and 23.53% in the control group.Â Conclusion: The effect of comfortable nursing on the preparationÂ of colonic gut in the oral magnesium sulfate method is relativelyÂ large.
Evaluation of Nursing Effect of Comprehensive Nursing Intervention on Elderly Patients with Severe Pneumonia
Authors: Hua Shuang Chen
Published: July 2021

Objective: To analyse and discuss the related aspects of theÂ nursing effect of comprehensive nursing intervention in elderlyÂ patients with severe pneumonia. Methods: 150 cases of senileÂ severe pneumonia were randomly divided into observation groupÂ and control group. 75 patients were distributed to each controlÂ group and observation group, the control group was applied withÂ conventional nursing intervention, observation group was appliedÂ with comprehensive nursing intervention, the two groups ofÂ clinical efficacy and quality of life and related care satisfactionÂ were compared.Â Results:Â The effective rate of treatment wasÂ 90.67% (68/75) in the observation group, which was significantlyÂ higher than that in the con-trol group (74.67%, 56/75), P<0.05; theÂ observation groupâ€™s body function and mood and role, socialÂ function (P<0.05) were significantly higher than that in the controlÂ group. The satisfaction rate of the observation group was 96.00%Â (72/75), which was significantly higher than that of the controlÂ group (82.67%) (62/75), P<0.05.
Application of PDCA Circulatory Model in Digestive Endoscopic Nursing
Authors: Jian Qin
Published: July 2021

Objective: To explore the application of PDCA circulatory modelÂ in hospital digestive endoscopic nursing and its application.Â Methods: 48 patients were randomly selected from the controlÂ group, and the patients were treated with a routine nursingÂ operation. Eight patients with digestive endoscopy were selectedÂ as the observation group. On the basis of the implementation ofÂ general care and then increase the PDCA cycle model, and then theÂ two groups of patients with a detailed comparison of care andÂ research. Results: The nursing quality and satisfaction of theÂ observation group were higher than those of the control group, andÂ the contrast difference was significantly improved (P < 0.05).Â Conclusion: The full application of PDCA circulatory model inÂ digestive endoscopic nursing can effectively improve the quality ofÂ care for patients, and also improve the satisfaction of patients to aÂ certain extent.
Analysis on the Reasons of Reducing the Backwashing of Stomatological Equipment in Disinfection Supply Center
Authors: Li Xue
Published: July 2021

In the disinfection supply center, it is possible to improve thequalified rate of cleaning, to ensure the success of sterilization, toprevent and control the occurrence of infection in stomatologicalhospital. Methods: A total of 18,857 oral instruments were washedfrom July to October 2015 and January to April, respectively, and2,040 pieces were returned. Through analysis and comparison, thefactors related to the increase of the instrument washing rate wereanalyzed and tracked. The results showed that the rinsing rate oforal instrument was reduced from 14.17% to 7.63%. Conclusion:In the hospital disinfection supply center equipment before theimplementation of pretreatment and classification equipment intothe mouth of the cleaning basket, to improve the cleaning pass rate,and reduce the back to work.
Study on the Relationship Between Folate, Dna Methylation and Esophagus Cancer
Authors: Guiling Huang
Published: July 2021

Esophagus cancer is a common malignant tumor in China, and itsprevalence rate and fatality rate are the highest in the world whoseoccurrence is related to multiple factors, including family heredity,race, gender, region, diet and so on. Esophagus cancer is the diseasewith the most Chinese characteristic. The pathogenesis of esophagusÂ cancer is very complicated, and the epigenetics in the pathogeneticÂ process has become the current research hotspot, and the reversibleÂ feature provides a new direction for the early screening, preventionÂ and treatment of esophagus cancer. DNA methylation is the mostÂ deep epigenetics in the current study, and the pattern of genomeÂ methylation is often abnormal in the cancerization of esophagusÂ cancer. The folate, as the methyl group donor, and B-vitaminsÂ related to one-carbon metabolism, shall directly influence theÂ condition of DNA methylation, give rise to the change of epigenetics,Â affect the occurrence of esophagus cancer. This paper summarizesÂ the relationship among the occurrence of esophagus cancer andÂ folate, several kinds of B-vitamins related to one-carbon metabolism,Â DNA methylation.
The Clinical Effects of Psychological Nursing in the Pediatric Intensive Care Unit
Authors: Yi Yang
Published: July 2021

Objective: To explore the effects of psychological nursing in theÂ pediatric intensive care unit. Methods: 110 cases of intensive careÂ of children from January 2014 to January 2015 were selected andÂ randomly divided into the observation group (n=55) and the controlÂ group (n=55). The children of the control group were given usualÂ nursing care, the patients of the observation group were givenÂ psychological nursing. On two groups of patients before and afterÂ the intervention of the SAS scores and SDS scores complianceÂ parents care quality satisfaction are compared. Results: BeforeÂ intervention, theobservation group of patients and the controlÂ group of patients with SAS scores and SDS scores difference no statistical significance (P > 0.05), and after the intervention, theÂ observation group patients' scores of SAS and SDS wereÂ significantly better than the control group, and the observationÂ group below the control group (P < 0.05). The observation group ofÂ compliance rate was 96.36%, and the control group of compliance rate was 69.09%, it below the observation (P<0.05). Parents careÂ quality satisfaction of observation group was obviously better thanÂ that of control group with that difference is statistically significantÂ (P<0.05). Conclusion: psychological nursing measures used inÂ pediatric intensive care unit has certain feasibility and is worthÂ popularizing clinically.
Management of Perioperative Target Blood Pressure in Bridging Therapy for Acute Ischemic Stroke
Authors: Zhu Lin , Wang Qinghong , Liu Cuncun
Published: July 2021

Abstract: Objective: To investigate the management of perioperative target blood pressure in the treatment of acute ischemic stroke with intravenous thrombolytic bridging. Methods: Retrospective analysis of the blood pressure management and nursing experience of 36 patients with acute ischemic stroke who received endovascular treatment with bridge mode from November 2017 to January 2019 in our hospital. Through correct monitoring of basic blood pressure, rapid and stable blood pressure reduction before the bridge treatment, close cooperation during the operation, and close observation and treatment of postoperative blood pressure fluctuations, the patientâ€™s blood pressure can be controlled within the target range. Results: The blood vessels of 36 patients were partially or completely recanalized after treatment. Clinical outcomes: Two cases died. After 90 days, 29 patients with good clinical outcomes were followed up, and 5 patients with poor clinical prognosis. Conclusion: Effective blood pressure management is a necessary measure in the perioperative period of bridging therapy for patients with acute ischemic stroke, which can reduce the postoperative complications of patients treated with bridging therapy, obtain good therapeutic effect and improve the prognosis of patients.
Brief Analysis of Treatment of Postpartum Body Pain by Professor Zhang Xiaofeng from the Viewpoint of "Liver Vital Deficiency and Yang Stagnation"
Authors: Chen Luoxu , Zhang Xiaofeng
Published: July 2021

Postpartum body pain is a common gynecological disease in clinical setting. Its symptoms are complex and is difficult to treat. It is often treated in many ways but with poor results, which bring great pain to patients and their families. Professor Zhang Xiaofeng can effectively improve clinical treatment of this disease from the point of view of "liver vital deficiency and yang stagnation". This paper mainly introduces the professional experience of Professor Zhang Xiaofeng in treating postpartum body pain. A clinical case was attached for reference as proof.
Application of Quality of Life Scale in Hematological Disease Research
Authors: Du Zongyan , Yao Wenling , Li Min , Li Ping
Published: July 2021

Quality of life research is an emerging and rapidly developing health measurement technology. Quality of life assessment is performed using scales. Accurate quality of life assessment provides comprehensive information of patient which allows clinicians to put emphasis on overall quality of life (Total QOL) of patient. Quality of life scales have been applied for analysis of diseases such as leukemia and immune thrombocytopenia. This article reviews the use of commonly used quality of life scales for hematological diseases.
Analysis of Enteral Nutritional Value in Severe Craniocerebral Injury
Authors: Hu Kai
Published: July 2021

Objective: This study will analyze the clinical value of enteral nutrition treatment in patients with severe craniocerebral injury and discuss the safety of this treatment. Methods: This study selected patients who were treated in the hospital from January 2017 to December 2018. After the screening, all patients were diagnosed as severe craniocerebral injury. Forty-four patients who have met the experimental criteria were undergone enteral nutrition treatment to improve the condition. The success rate of catheterization and the changes in patient’s vital signs were analyzed. Especially the effect on the disease after the insertion of nasogastric tubing for nutritional treatment. Results: From the treatment results, the success rate of catheterization was 95.45% (42/44). In term of the timeline, the average was (36.5±2.7) min, the shortest time was 30 minutes and the longest time was no more than 5 minutes. The vital signs were stable before and after treatment and no complications such as arrhythmia. For those 42 successful patients, the average time for jejunal nutrition therapy was (36.2±4.1) days, the shortest was 27 days while the longest was 53 days and no adverse cases occurred. Conclusion: Enteral nutrition has a clinical application on patients with severe craniocerebral injury and can meet the nutritional needs of patients. Moreover, it has a high degree of feasibility and safety which is conducive to the early recovery of patients and has been well received.
Clinical Analysis on the Safety and Efficacy of 30 cm Short FURS in the Treatment of Multiple Nephrolithiasis in Children
Authors: Gu Deqiang , Guo Jingyang , Yang Wenzeng , An Feng , Cui Zhenyu , Li Yonggang
Published: July 2021

Objective: To evaluate the safety and efficacy of ultra-percutaneous nephrotic access combined with 30 cm FURS in the treatment of multiple nephrolithiasis in children. Methods: From October 2016 to March 2018, 30 children with multiple nephrolithiasis (age range 2 to 10 years old) were admitted to our hospital with ultra-perc combined with 30 cm FURS holmium laser lithotripsy The patients' operation time, hospitalization time, stone freel rate, blood loss before and after surgery, C-reactive protein, leukocyte, platelet and other stress factors, creatinine, urea nitrogen and other indicators of renal function, Renal scintigraphy was used to evaluation the injury of renal parenchymal. Results: The use of ultra-perc combined with 30 cm FURS, the first lithotomy was 93%, 2 patients were staged surgery, staging clearance rate of 100% (30/30) operation time 20 to 50 minutes, the average 35 minutes, average postoperative hospital stay 2 days, postoperative hemoglobin decreased no significant change. No transfusion in children, before and after surgery creatinine, urea nitrogen and CRP leukocytes, platelet and other grades were no significant differences, in Renal scintigraphy renal parenchymal injury was not obvious. Follow-up from 6 months to 1 year, no long-term complications in all children. Conclusion: Ultra-percutaneous nephrotic access combined with 30 cm FURS in the treatment of multiple nephrolithiasis in children is safe and effective.
Professor Xiaoping Liu 's experience in treating adenoid hypertrophy in children
Authors: Luo Tuo , Liu Xiaoping
Published: July 2021

[Abstract]: Adenoidal hypertrophy is a common clinical disease in children, and repeated episodes have serious effects on children's learning and life. This article introduces Professor Liu Xiaoping's experience of treatment and pathogenesis analysis of adenoid hypertrophy in children, according to the understanding of Chinese medicine physicians to this disease, which offers new idea and methods to the treatment of adenoidal hypertrophy in children.Ancient Chinese medicine's understanding of the disease, Treatment of adenoidal hypertrophy provides new ideas and methods.
Effect of iRoot BP Plus Pulpotomy for Immediate Repair in Children with Young Permanent Teeth Crown Fracture
Authors: Song Jiaying
Published: July 2021

Objective: To explore the clinical effect of iRoot BP Plus pulpotomy for immediate repair in children with young permanent teeth crown fracture. Methods: From September 2017 to October 2018, 80 children (80 affected teeth) with young permanent teeth crown fracture who treated in the hospital were selected as the research objects. Random number table method was used to divide them into observation and control groups with each group of forty patients (40 affected teeth). The children in the control group were treated with calcium hydroxide resin, while the observation group were treated with iRoot BP Plus for immediate repair. The surgical success rate was compared between the two groups, and the pulp vitality before and after treatment were compared. Results: At 3 months and 6 months after surgery, the success rate of children in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). The percentage of children with negative pulp activity in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Immediate repair with iRoot BP Plus pulpotomy in children with young permanent teeth crown fracture has significant clinical effect.
Effects of High-Flux Hemodialysis on Inflammatory Factors and Nutritional Status in Patients with Severe Renal Failure
Authors: Li Jibo , Li Xiwen , Wang Gang , Jiang Peiqin
Published: July 2021

Objective: To investigate the effects of high-flux hemodialysis on inflammatory factors and nutritional status in patients with severe renal failure. Methods: A total of 72 patients with severe renal failure who underwent dialysis treatment in the hospital from January 2017 to March 2019 were selected as the research subjects, and they were randomly divided into 2 groups with 36 patients each. The control group underwent low-flux hemodialysis, and the observation group underwent high-flux hemodialysis. The levels of inflammatory factors and nutritional status were compared between the two groups after treatment. Results: The levels of various inflammatory factors in the observation group were lower than those in the control group and the nutritional indexes were higher than those in the control group after 4 weeks of treatment (P<0.05). Conclusion: High-throughput hemodialysis in patients with severe renal failure can significantly reduce the levels of inflammatory factors and improve nutritional status.
The Value of c-TCD in the Diagnosis of Migraine and Cryptogenic Stroke Caused by PFO
Authors: Yu Xinyan , Yang Jianyun , Wu Dan
Published: July 2021

Objective: To investigate the value of contrast-enhanced transcranial doppler (c-TCD) in the diagnosis of patent foramen ovale (PFO) of patients with migraine and cryptogenic stroke. Methods: A retrospective analysis of 160 patients undergoing c-TCD monitoring in our hospital from June 2014 to June 2019 was performed. Among them, there were 80 cases of patients with migraine (38 cases with aura and 42 cases without aura) in group A, and 80 cases of patients with cryptogenic stroke in group B. The positive detectable rate of PFO in the two groups were calculated and analyzed. Results: The detectable rate was 50.00% in group A, and 40.00% in group B. There was no statistical significance between the two groups (P> 0.05). Among them, the detectable rate of PFO in migraine with aura in group A (62.50%) was higher than that in group B(37.50%). The difference was statistically significant (P<0.05); In the two groups of PFO-positive patients, the difference didn’t have statistical significance, comparing the proportion of the inherent type to that of potential type (P>0.05); There was no statistical significance of the difference between the RLS incidence of grade I and that of grade II among two groups of PFO-positive patients (P>0.05); the incidence of RLS in grade III in group B (50.00%) was higher than that in group A (25.00%), and the difference was statistically significant (P<0.05). Conclusion: c-TCD can accurately screen migraine and cryptogenic stroke caused by PFO, and grade and classify it as a clinical diagnosis of migraine and cryptogenic caused by PFO. It can also act as a objective reference of estimating the effect of treatment in different diseases and preventing cryptogenic stroke.
The Efficacy Analysis of Transbronchoscopic Large Volume Lung Lavage in Treatment of Pneumoconiosis Complicated with Chronic Obstructive Pulmonary Disease
Authors: Chen Lijun , Xu Wang , Ma Xiaoyong , Ma Xiuqin , Liu Yanhong , Chen Chao
Published: July 2021

Objective: To evaluate the efficacy of transbronchoscopic large volume lung lavage in the treatment of pneumoconiosis complicated with chronic obstructive pulmonary disease (COPD). Methods: The clinical data of 80 patients with pneumoconiosis complicated with COPD admitted to our hospital from June 2017 to January 2019 were retrospectively analyzed. 40 patients in the control group were treated with conventional drugs and 40 patients in the observation group treated with conventional drugs plus transbronchoscopic large-volume lung lavage. Dyspnea score and healthy quality of life were compared between the two groups. Results: the scores of dyspnea in the observation group were significantly lower than those in the control group at 12, 24 and 48 weeks after treatment, and the (SGRQ) scores of George's respiratory problems questionnaire in the observation group were significantly lower than those in the control group at 12, 24 and 48 weeks after treatment. Conclusion: Thetransbronchoscopic large volume of lung lavage has a significant effect on the treatment of pneumoconiosis patients with COPD, which can effectively reduce the degree of dyspnea and improve the quality of life.
The Application of Layered Progressive Teaching Method in Nursing Teaching of Health Management Centre
Authors: Liu Xin , Qu Xiaoying
Published: July 2021

Objective: To explore the clinical effect of the layered progressive teaching method in the process of nursing teaching in the health management centre. Methods: 100 nursing students in the health management centre of our hospital were randomly divided into two groups from April 2018 to April 2019, in which students of the control group were treated with routine teaching, while those of the experimental group were treated with layered progressive teaching. Then, the teaching effect of the two groups was compared and analysed. Results: The assessment results of nursing students in the two groups were compared, in which the theoretical knowledge scores and practical operation scores of nursing students in the experimental group were (94.34 ± 2.33) and (90.45 ± 2.20) respectively. By contrast, the score of students in the control group was lower and the difference between the two groups was not significant (P<0.50). The teaching effect of students in the experimental group is more significant. Conclusion: During the process of nursing teaching in the Health Management Centre, the progressive teaching method showed a significant clinical effect and could effectively enhance students’ scores. Therefore, it is positively significant for clinical development.
Practice and Exploration of Interview in Hospital Public Recruitment
Authors: Wang Danruo , Chen Yong
Published: July 2021

Afterentering the era of economic knowledge, for the development of enterprises, the role of human resources in enterprise development is more important than material resources, for which, hospitals have no exception. With the continuous development of the society and the continuous progress of the medical industry, in order to meet the medical service needs of the general public, hospitals must expand their scale, which requires seeking more human resources. The interview is a very important link in the hospital’s public recruitment. The author explores and analyzes the current situation of the practice and application of interview, and puts forward the practical application and exploration strategy of the interview in hospital public recruitment, hoping to help improve the hospital's human resources.
Therapeutic Effect of Chinese Massage Combined with Warm Acupuncture on Knee Osteoarthritis
Authors: Wang Fuli
Published: July 2021

Objective: To investigate the effect of Chinese massage combined with warm acupuncture on knee osteoarthritis. Methods: 60 patients with knee osteoarthritis who were treated in our hospital from January 2017 to October 2019 were selected as the research subjects, and they were randomly divided into 2 groups of 30 patients each. The control group was treated with oral western medicine, and the observation group was treated with massage combined with warm acupuncture. The clinical efficacy and WOMAC index were compared between the two groups. Results: The total effective rate of the observation group was higher than that of the control group, and the WOMAC score was lower than that of the control group. The difference was statistically significant(P<0.05). Conclusion: Chinese massage combined with warm acupuncture is effective in treating knee osteoarthritis It can effectively alleviate the symptoms of pain and joint stiffness in patients, and improve joint mobility, which is worth for clinical promotion.
Changes and Clinical Value of Serum Cortisol Levels in Patients with Hypertensive Disorder in Pregnancy
Authors: Huo Gaoxiang , Qin Yeqiang , Bao Xiucui , Yao Xiaoling , Pu Zhangwei , Sun Jia
Published: July 2021

Objective: To investigate the changes and the corresponding clinical value of serum cortisol levels in patients with hypertensive disorders during pregnancy. Methods: In this study, 90 patients with different degrees of hypertensive disorders during pregnancy who were admitted from August 2018 to August 2019 in our hospital were set as the research objects. 90 cases were grouped according to the diagnostic criteria in Obstetrics and Gynecology, including 30 cases in each of the hypertension group, the preeclampsia group, and the eclampsia group. Another 30 healthy pregnant women were selected as the control group. The serum cortisol levels of pregnant women in the above four groups were measured. Results: Compared with the control group, the serum cortisol levels in the other three groups were significantly increased. In perinatal outcome, compared with the control group, the three groups of patients had an increase in Apgar score, preterm birth, stillbirth rate, growth restriction rate and neonatal asphyxia rate. There were significant differences between groups (P <0.05), and showed as gestational hypertension <preeclampsia <eclampsia. Conclusion: With the exacerbation of hypertensive disorders during pregnancy, the serum cortisol level continues to increase, which has a serious adverse effect on the prognosis of the perinatal infants.
The Study on the Clinical Features and Prognosis of Pregnancy-related Breast Cancer
Authors: Zheng Dongxing , Jin Jihai , Zhang Qun
Published: July 2021

Objective: To explore the clinical features of pregnancy-related breast cancer and the related factors affecting the prognosis. Methods: The research work was carried out in our hospital from January 2018 to January 2019. In this study, 50 patients were selected as related breast cancer patients and 50 non-pregnancy related breast cancer patients were selected as control group. The clinical characteristics and prognosis of the two groups were compared and analyzed. Results: According to the incidence of pregnancy-related breast cancer, the onset of breast cancer is in pregnancy and lactation, with more than half of the total number of patients having two or more pregnancies and 74.0% of the patients having breast feeding history. In the two groups, most of the patients went to see a doctor because of palpable breast masses, and the average maximum diameter of tumors in PBC group was (5.13 ± 3.22)cm, including 5 cases accompanied by dimple sign, 7 cases accompanied by nipple depression, 8 cases accompanied by inflammatory changes of skin, 3 cases with pathological changes involving whole milk, and 27 cases (54.00%) with palpable axillary enlarged lymph nodes on the same side. The average maximum value of tumor in Non-PABC group was (3.94 ± 2.11) cm, with 5 cases accompanied by dimple sign, 4 cases accompanied by nipple depression, and 9 cases (18.00%) with palpable axillary lymph nodes on the same side. Conclusion: As far as pregnancy-related breast cancer is concerned, the clinical misdiagnosis rate is relatively high and the prognosis is poor. Prenatal examination and breast-feeding breast cancer examination are needed to ensure early detection and diagnosis. This is the key factor to ensure the survival rate of pregnancy-related breast cancer patients and has positive significance for clinical development.
Risks of CRISPR Gene Editing and An Answer to Them
Authors: Li Emily
Published: July 2021

CRISPR gene editing is a technology used to edit genomes of a variety of organisms like bacteria, animals or even human beings. Currently, there are various criticism concerning CRISPR since the technology is still immature. It’s important to address these concerns to ensure that CRISPR wouldn't cause harms to the society. The purpose of this investigation is to summarize methods which can be used to solve the risks and ethical issues regarding CRISPR through examining published researches in-depth. To draw a conclusion, scientists can use anti-crispr protein to minimize the off-target effects. For immunity issues, scientists can employ immunosuppressive drugs or to use CRISPR in places where immune system cannot reach. What’s more, given both legal and ethical hurdles, the problem of designer babies and bio-weapons are unlikely to happen. Therefore, although there are various concerns regarding CRISPR, scientists are figuring out ways to minimize the risks and to optimize the usage of the CRISPR.
Effect of Early Controlled Hypotension on Patients with Traumatic Brain Injury
Authors: Liu Yong
Published: July 2021

Objective: To investigate the clinical effect of early controlled hypotensive therapy in patients with traumatic brain injury (TBI). Methods: 68 patients with acute TBI in our hospital were selected for this investigation. They were evenly divided into a control group and an observation group according to the difference of blood pressure and basic level, whose lesion area after treatment, postoperative intracranial pressure after 2d and 7d, and GCS score of prognostic quality before and after treatment were made comparison. Results: The post-treatment lesion area of the observation group was lower than that in the control group (P<0.05); the postoperative intracranial pressure after 2d and 7d of the control group was better than the observation group(P<0.05), and the same with GCS score, which has statistical significance (P<0.05). Conclusion: Early controlled hypotensive therapy has a significant clinical effect on patients with brain trauma, it can reduce the lesion area after treatment and postoperative intracranial pressure as well.
Observations on the Application of Nursing Risk Management in the Care of Critically Ill Patients in the Respiratory Unit
Authors: Sun Yannan
Published: July 2021

Objective: Investigate the effectiveness of nursing risk management in the care of critically ill patients in the respiratory unit. Methods: Among the critically ill respiratory patients admitted to our hospital between May 2019 and April 2020, 78 patients were randomly selected and divided into an observation group and a control group, each consisting of 39 patients. In the observation group, a nursing risk management model was implemented, i.e., patients' clinical symptoms were observed at any time to monitor their treatment satisfaction and the effectiveness of their care and routine care was implemented for the control group. Results: The heart rate, respiratory rate, and pH of patients in the observation group were more stable than those in the control group, and their respiratory status was better, with differences in data. There was also significant statistical significance (P<0.05). The incidence of patient-provider disputes, unplanned extubation, and unplanned events were lower in the observation group compared to the control group, and their data difference was statistically significant (P<0.05). The treatment satisfaction as well as the total effective rate of patients in the observation group was also much higher than that of the control group, and there was also a statistically significant difference in the data (P<0.05). Conclusion: The nursing risk management model has a significant therapeutic effect in the care of critically ill respiratory patients. Therefore, it is worth popularizing to use in the clinical nursing of respiratory critical patients.
Relationship Research of PPAR-r Gene Polymorphisms with Adiponectin and Leptin in Type 2 Diabetes Mellitus
Authors: Feng Jia , Wang Shujin , Zuo Hong , Liu Xufeng , Li Guohong , Yu Niu
Published: July 2021

Objective: To investigate the peroxisome proliferator-activated receptor-? (peroxisome) in patients with type 2 diabetes mellitus. Proliferators-activated receptors-?, PPARs-? (?) gene polymorphisms about serum lipofuscin and leptin. Methods: One hundred and twenty patients with type 2 diabetes admitted to our hospital from June 2015 to June 2018 were selected. The patients were divided into an obese group and a non-obese group of 60 patients each according to their waist circumference. A polymerase chain reaction-length polymorphism protocol was implemented in all patients to explore the PPAR-? gene polymorphism, and blood glucose, lipid, adiponectin and leptin levels were measured in both groups. Results: PPAR-? gene polymorphisms in type 2 diabetic patients were dominated by wild-type homozygous; The levels of total cholesterol, triglyceride and LDL cholesterol in the obese group were significantly higher than those in the non-obese group, while the levels of HDL cholesterol were lower than those in the non-obese group. There is significant difference in comparison between groups (P<0.05) Those carrying the A allele had a significant lipid disorder profile and decreased adiponectin levels. Conclusions: PPAR-? gene polymorphisms in type 2 diabetes are not significantly associated with adiponectin and leptin, and only in the obese group, the patients with the Allele A showed significant dyslipidemia and a declining trend of adiponectin levels.
Advances in Acupuncture and its Associated Therapies for the Prevention and Treatment of Obesity Type 2 Diabetes Mellitus
Authors: Zhang Kaiya , Ren Yuanyuan , Zhou Yanyan
Published: July 2021

Obesity type 2 diabetes mellitus is a common metabolic disease in clinical practice, and its prevalence is increasing rapidly with the aging of the population and changes in lifestyle. Acupuncture, as a distinctive therapy, has its unique advantages in the treatment of obesity type 2 diabetes and has an irreplaceable role in a variety of treatment methods. The author organized the literature on acupuncture and its related therapies to prevent and treat obesity type 2 diabetes in recent years and found that acupuncture and its associated therapies to prevent and treat obesity type 2 diabetes mainly include: simple acupuncture, electroacupuncture, acupoint catgut embedding therapy, auricular-plaster therapy and other treatments, all of which can safely and effectively improve clinical symptoms, acupuncture and its related therapies to treat obesity type 2 diabetes has a broad prospect, worthy of further clinical promotion.
Early Imaging Features and Differential Diagnosis of Novel Coronavirus Pneumonia
Authors: Jiang Xiaofeng , Ma Xuyang , Zhang Tao , Kong Yanliang , Cai Lei , Lv Lin , Shao Yanli , Bai Jiangtao , Liu Lianfeng
Published: July 2021

Objective: To discuss the early imaging features of novel coronary pneumonia (NCP) and its differential diagnosis with common pneumonia for the clinical Provide relatively correct imaging diagnosis. Methods: A review of 10 cases of novel coronavirus pneumonia diagnosed in our hospital and surrounding counties was collected, and our hospital's 2019-2020 Common pneumonia such as influenza A and B virus pneumonia, lobar pneumonia and adenovirus confirmed by laboratory tests and abnormal chest radiographs Ten patients each with pneumonia, a total of 40 patients, were collected and their imaging features were analyzed. Results: In 10 patients with neo-coronary pneumonia, there were 30 lesions on chest CT, with typical characteristic lesions containing bronchograms within their Angiographic thickening; located in the subpleura, with grinding glass-like or combined solid changes, referred to as "extratubular halo", with multifocal and multifocal distribution. Morphology or unilobular large lamellar foci without lymph node enlargement and pleural effusion; 10 cases of influenza A and B virus pneumonia in chest CT performance In nine patients, the lesions were distributed in the subpleural or along the perimeter of the bronchial vessels in the form of an analogous circular ground-glass shadow, some of which was a small piece of solid shadow, 1 The case involved a single lobe of the lung and showed a large mixed ground glass image, and the CT in 10 cases of lobar pneumonia showed that they all had a single large solid lobe The variegated shadow or patchy cloud with blurred margins was triangularly altered with the tip pointing to the lung portal, and there were five cases of air-containing bronchograms. Adenoviral pneumonia is more common in infants and young children, and CT showed single or multiple grinded glass images in both lungs with patchy solid variegated shadows and lobar distribution. Conclusion: NCP and common pneumonia have certain imaging features that, in combination with laboratory tests and epidemiologic history, allow a preliminary diagnosis to be made. It has certain directions and help for clinical diagnosis.
Verification and Improvement of the MTT Method for in vitro HSS Bioactivity Activity Determination
Authors: Liu Ang , Xu Wei
Published: July 2021

To optimize the experimental conditions of MTT colorimetric assay for HSS bioactivity in vitro, we studied the optimal combination of the major conditions of the MTT assay by orthogonal test and other experiments, and compared HSS bioactivity in vitro measured by the improved MTT protocol and published MTT assay at serial protein doses. Results showed that the absorbance value (A value) of the MTT assay directly correlated with the number of human hepatoma cell lines SMMC7721. The result of orthogonal test was the number of 5×104 SMMC7721 cells/ml, culture period 6 h before adding HSS, concentration of HSS 100 ?g/ml, incubation time with HSS 36 h. Additionally, several experiments demonstrated the optimal combination of other conditions was 50 ?g MTT, incubation time for MTT 6 h, DMSO was used to dissolve the MTT formazan crystals and measured with ELISA scanner at 570 nm. The result of determining HSS bio-activity in vitro by optimized MTT protocol showed that sHSS bio-activity increased with the growth of protein dose, but decreased when it beyond a certain dose. The optimized MTT protocol was a sensitive, convenient and stable quantitative method to evaluate HSS bio-activity.
The Influence of Neuman Theory Based Stress Management on the Level of Benefit Finding in Postoperative Breast Cancer Patients
Authors: Dai Qin , Hang Huili , He Chunxiu , Zhou Yuwen , Zhang Jing
Published: July 2021

Objective: To explore the influence of stress management program based on Neuman theory on the level of benefit finding in postoperative breast cancer patients. Methods: Using convenient sampling method, 60 postoperative breast cancer patients in the tumor ward of a hospital were selected and randomly assigned into observation group (n=30) and control group (n=30). The control group adopts the conventional postoperative psychological nursing program, and the observation group adopts the stress management program based on Neuman theory for psychological nursing. The differences in benefit finding, life quality, and medical coping strategies between the two groups before and after nursing were compared. Results: After the implementation of the two nursing programs, the level of benefit finding, life quality, and medical coping strategies of patients in the observation group were higher than those in the control group (t1=3.996, t2=4.662, t3=4.113, P?0.05); there was a statistically significant difference in the level of benefit finding, life quality, and medical coping strategies of patients before and after the implementation of the two nursing programs(P?0.05). Conclusions: The stress management strategy based on Neuman theory can improve patients’ state of psychological stress coping, play a positive role in guiding the psychology of patients after breast cancer surgery, and can be used as a reference for the psychological nursing program of postoperative patients.
Photodynamic Therapy for Low-grade Cervical Intraepithelial Neoplasia (CIN1): A Case Report
Authors: Zhang Yinyin , Lin Hong , Fan Huizhen
Published: July 2021

As a drug-mechanical combination technology, photodynamic (PDT) can achieve accurate and targeted therapy for malignant tumors and benign diseases through the production of reactive oxygen species, oxygen free radicals or singlet oxygen by photosensitizers at specific wavelengths. Compared with traditional surgery, it has the advantages of selective killing, repeatable treatment, preserving target organ function and so on. The purpose of this study was to explore the clinical value of photodynamic therapy in cervical precancerous lesions by taking the patients with low-grade cervical intraepithelial neoplasia (CIN1) with high-risk human papillomavirus (HR-HPV) persistent infection diagnosed by "three-step diagnosis and treatment procedure" as an example. Using HiPorfin as a photosensitizer, photodynamic therapy was performed 48 hours after intravenous drip. Set laser wavelength 630nm, light dose density 137.58J/cm2, transmission efficiency 1.42, output power 2w. 3cm columnar optical fiber was placed around the 2cm in the cervical canal to cover all the lesions, and the irradiation time was 900s (600s in the cervical canal and 300s outside the cervical canal). The patients were given oxygen inhalation for 6 hours after operation, and the patients were observed for itching and other discomfort, and paid attention to avoid light. Photodynamic therapy was performed again in the same way on the second day. After two months of treatment, pathological biopsy showed chronic cervicitis, indicating that the disease had been effectively controlled. Theoretically, although the patient is not the absolute indication of photodynamic therapy (that is, meeting CIN ? or CIN ?, having fertility requirements and not undergoing surgery), this therapy can remove not only the superficial lesions inside and outside the cervix, but also the potential lesions not found under colposcopy. It can also block the persistent infection of HPV by inhibiting the expression of HPV18, E6 and E7mRNA in Hela cells. In combination with Baofukang suppository, it can block HPV infection. Increase the negative conversion rate of cervical HPV and reduce the probability of recurrence after CIN1 cure. For young female patients with persistent HR-HPV infection and fertility requirements, photodynamic therapy is an effective choice for clinical treatment of CIN1.
Photodynamic Therapy for Advanced Rectal Cancer: A Case Report
Authors: Chen Lemei , Liu Yanping , Xie Ping , Fan Huizhen
Published: July 2021

Objective: To investigate the potential value of PDT(photodynamic therapy) in the treatment of rectal cancer by reviewing the diagnosis and treatment process of a patient with advanced rectal cancer who lost the opportunity of surgery. Methods: Select the case data of a patient receiving photodynamic therapy in our hospital, and analyze the photodynamic mechanism, safety and efficiency, and discuss the efficacy of photodynamic therapy. Results: After the patient received photodynamic therapy, re-examination of the endoscopy showed that the intestinal cavity was smoother than before, the bowel was difficult, and the symptoms of blood in the stool improved. Conclusion: Photodynamic therapy can be used as a radical or palliative treatment for clinical tumor treatment. Because of its advantages of minimally invasive, tissue-specific, repetitive and synergistic radiotherapy and chemotherapy, it plays an important role in early or middle-advanced colorectal cancer and is worthy of clinical promotion.
Feasibility of Recruiting and Assessing Health-Related Quality of Life and Physical Function in Older Chinese Adults with Cerebral Infarction
Authors: Wang Weiyu
Published: July 2021

Objective: While it is known that exercise therapy can improve physical and emotional function in cerebral infarction (CI) patients, few studies have examined how well this would be accepted by older adults in China. Methods: In this study, the feasibility of recruiting and assessing health-related quality of life and physical function in older Chinese adults with cerebral infarction was assessed. Specific aims of the study were to evaluate the feasibility of recruiting older adults, with and without CI, from three different locations/settings in China; Compare the quality of life and physical function measures between CI and control subjects; Propose future larger randomized controlled studies of aerobic and resistance exercise training in both human and animal models after CI. Results: Overall, 66/275 (24.0%) surveys that were sent to older Chinese adults were returned and evaluated. Of those surveys returned, 18 (27%) met the study inclusion and exclusion criteria. Consequently, the results of this feasibility study indicate there is a recruitment yield (number of subject contacted/number of subjects who qualified for study) of 6.5%. These number varied at the different sites/settings, but the highest recruitment yield was seen in hospitalized patients. Despite small sample sizes, there were statistically significant differences in health-related quality of life and physical function between CI patients and control subjects. Conclusion: This feasibility study demonstrated that it is possible to successfully recruit CI patients for an exercise intervention study as well as to perform important assessments of health-related quality of life and physical function. Further randomized controlled trials, in humans and animal models, will be needed determine if aerobic and/or resistance exercise training can improve health and physical function in older CI patients. Additional studies will be needed to determine the specific mechanisms responsible for the benefits see with aerobic and resistance training.
Investigation on Blood Glucose Control Nursing of ICU Severe Patients
Authors: Guo Shoutao
Published: July 2021

Objective: To analyze the effect of blood glucose control nursing in intensive care unit (ICU) patients. Methods: The clinical data of 70 severe patients in ICU of our hospital from January 2019 to May 2020 were retrospectively analyzed. The clinical data of 34 patients with routine intervention were divided into the control group, and the clinical data of 36 patients with routine intervention and blood glucose control nursing were divided into the observation group, all were intervened for 14 days. The blood glucose levels and prognosis of the two groups were compared before intervention and at the end of 14 days of intervention, the time required to achieve the standard blood glucose level of the two groups was recorded. Results: After 14 days of intervention, the fasting blood glucose level of the observation group was lower than the control group, the difference was statistically significant (P < 0.05); the time of blood glucose reaching the standard in the observation group was shorter than that in the control group, the difference was statistically significant (P < 0.05); on the 14th day of intervention, the sequential organ failure assessment score (SOFA) score of the two groups was lower than before intervention, the SOFA score of the observation group was lower than control group, the difference was statistically significant (P < 0.05). Conclusion: The effect of blood glucose control nursing in ICU is better, which effectively controlled the blood glucose level of patients and improved the prognosis of patients.
Research on the Quality Management of Apprenticeship Education at “Famous Senior TCM Physician Studio”
Authors: Yan Nana , Zhang Hongxing , Tan Cong
Published: July 2021

"Inherited the traditional education" is the main mode of talent cultivation of traditional Chinese medicine and effective way, in order to better promote the heritage and development of TCM cause, let "famous old Chinese medicine studio" play in training talents, academic communication, scientific research, service people should have a role to promote the region's traditional Chinese medicine clinical ability, our college of traditional Chinese medicine (TCM) based on a studio conducted to old with the new educational background education, the author use the PDCA circulation method in management of "famous old Chinese medicine studio" education "shicheng" quality management is improved and exploring, significantly improved the team of teachers and students both sides of teaching and learning satisfaction, At the same time, it has effectively promoted the overall level of TCM medical treatment in our hospital.