bluuebunny/crossref_metadata_2025 huggingface dataset:
Pembuatan Alat Pemantauan Kualitas Air Sungai di Kelurahan Tirta Siak, Kota Pekanbaru
Authors: Nurhalim Nurhalim , Marpaung Noveri Lysbetti , Anhar Anhar , Rajagukguk Antonius , Suwitno Suwitno
Published: December 2021

Kegiatan Pengabdian kepada Masyarakat Terintegrasi Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Riau merupakan kegiatan Pengabdian kepada Masyarakat dosen yang dijalankan secara bersamaan dengan kegiatan Kuliah Kerja Nyata (KUKERTA) mahasiswa. Kegiatan pengabdian ini dirancang berdasarkan kebutuhan masyarakat lokasi Kukerta. Kegiatan pengabdian kali ini berupa penerapan ilmu pengetahuan dan teknologi dengan merancang sebuah alat Sistem Smart Monitoring Kualitas Air berbasiskan internet of thing (IoT) di Kelurahan Tirta Siak, Payung Sekaki, Pekanbaru. Alat ini mengubah cara pengujian air baku yang konvensional yang biasanya dilakukan dengan cara membawa sampel ke laboratorium. Sistem Smart Monitoring Kualitas Air Sungai ini menguji sampel air dengan meletakkan sensor kekeruhan dan pH di lokasi yang ditentukan, kemudian data diproses oleh Arduino Mega 2560 untuk melakukan pembacaan nilai parameter pH dan kekeruhan air sungai, nilai yang didapat dari proses pengukuran tersebut dikonversikan dari bentuk analog ke bentuk digital untuk ditampilkan ke antar muka berupa website. Dengan adanya alat ini diharapkan kualitas air Sungai Siak di titik lokasi dimana alat dipasang dapat terpantau. Sehingga dengan adanya pemantauan secara langsung dengan data real time ini dapat pula merubah perilaku masyarakat terutama masyarakat Pekanbaru terhadap kualitas air Sungai Siak dengan demikian kebersamaan masyarakat dalam menjaga kualitas lingkungan akan terbangun.
The Independence Process of Bulgaria and the First Ambassador of the Ottoman Empire to Sofia, Mustafa Asım Bey
Authors: Temizer Abidin
Published: December 2021

In this study, the reaction of the Ottoman Empire to the declaration of independence of Bulgaria, the first ambassador of the Ottoman Empire in Bulgaria, Mustafa Asım Bey and his activities are discussed.

The study examines the diplomatic activities of the Ottoman Empire against Bulgaria in the period between the autonomy process of Bulgaria and the independence process, the process of recognition of Bulgaria’s independence, the diplomatic relations established with Bulgaria, the biography of Mustafa Asım Bey, the first Ambassador of the Ottoman Empire to Sofia, and his approach to the problems between the two countries.

In the article, documents from the Ottoman Archive of Directorate of State Archives (BOA), documents from the Bulgarian State Archives, periodicals and literature were used.
The Lymphatic Pump Technique for the Treatment of the Lower Limb Lymphedema
Authors: Bergna A. , Panigada L. , Benussi F. , Buffone F. , Caruana C. , Castrignano M. , Ciancone E. , Cazzaniga F. , Sotgiu A. , Bressan V. , Bressan L.C. , Solimene U.
Published: December 2021

Lymphedema is a condition occurring when the lymphatic system fails to efficiently transport the lymph, thus creating a fluid accumulation in the interstitial space. As of today, the rehabilitation treatment for lymphedema relies on the principles of Complete Decongestive Therapy (CDT), a series of treatments designed to favor the reabsorption of the lymph by the lymphatic system and to restore the functionality of the affected limb. From an osteopathic point of view, interesting results have been obtained through Lymphatic Pump Technique (LPT), a series of oscillatory techniques applied to different areas of the body such as chest, abdomen and feet. A few LPT studies on animals have shown a significant improvement not only in the lymphatic system efficiency (an increase of 271% in lymph flow) but also in the immune system.
Aim. From the scientific evidence derived from such studies, in this paper we propose a clinical trial aiming to demonstrate the benefits that this technique can bring to human beings in a specific rehabilitation process following a lower limb lymphoedema.
Material and methods. An indirect volumetric measurement of lymphedematous limbs according to the segmental technique was performed on six subjects having a history of CDT treatments with different clinical histories, age, gender, work and sport characteristics.The results of the study group treated with the LPT were compared to the results of the same subjects who previously underwent CDT treatment only. The LPT was applied in 8 sessions for two weeks, i.e. for the period of time scheduled for normal physiotherapy rehabilitation including CDT.
Results. The average volume before CDT was 9470.6 ml while after treatment was 8429 ml. The mean volume before CDT associated with LPT was 9608.5 ml, whereas after treatment the mean was 8267 ml with a significant reduction in lymphoedema.
Conclusions. Despite the small number of cases examined, the treatment described in this project has led to positive and statistically significant results, in terms of absorption of lymphedema, especially reducing the volume of the limb. LPT is safe as it is a non-invasive technique, performed with the application of light forces, and integrates perfectly with the CDT.
Adjunctive Physiotherapy – A Case Report on the Management and Effective Treatment of Diabetic Neuropathic Foot Ulcer Using Adjunctive Physiotherapy
Authors: Colpin M.
Published: December 2021

Physiotherapy must be considered and reprioritized as an adjunctive medical service for long term health and rehabilitation. Comprehensive physiotherapy has the potential to be administered in out-patient rehabilitation facilities, hospitals, and Thermal Health Centers. A review of select adjunctive physiotherapy methods will be presented along with a case report of the successful treatment, with rationally selected physiotherapeutic agents, of a Diabetic Neuropathic Foot Ulcer scheduled for surgical amputation.
By highlighting this case, the author is attempting to bring attention to familiar and time-tested therapies that have fallen out of use in a primary intervention context. This case report aims to exemplify that the role for rational physiotherapeutic methods stretches beyond current mainstream applications.
Historical Context. Will supply the historical and foundational work in the field of physiotherapy that contextualizes the rational basis for the applications described in the case.
Therapies. Lists the physiotherapy methods highlighted in this case, reviews the mechanism of action, discusses the therapeutic application, and provides modern citation for the rationalization of the therapy.
Case Report. Reviews a detailed narrative of the case in review. Covers intake, case history, progression of case, as well as clinical applications for physiotherapy as they arise in the course of case management.
Conclusion. Reviews the emphasis for reconsidering the role of Physiotherapy in the primary management of acute and chronic illness.
Foreign Investments and Socialist Enterprise in Slovenia (Yugoslavia): The Case of the Kolektor Company
Authors: Lazarevic Zarko
Published: December 2021

In this article, I examine foreign investment in the socialist enterprise in the former Yugoslavia based on the case study of Kolektor in the context of the liberalized communist social and economic order. Foreign investments were allowed in the form of joint ventures. I present these investments from the viewpoint of economic reforms, the concept of socialist enterprise, and the concept of economic development, which enabled foreign investments and shaped regulation and the structure of foreign investments in Yugoslavia. The history of the case of Kolektor began at a time when Slovenia still belonged to the former Yugoslavia, which was arguably a liberalized type of communist economic system. This was during the Cold War, when both Europe and the rest of the world were divided essentially along the lines of the communist east and the capitalist west. The Kolektor Company was established in 1963 as a state socialist enterprise for the manufacture of the rotary electrical switches known as commutators. From the outset, the company tried to establish international cooperation to acquire modern technology. In 1968, it reached an agreement with the West German Company Kautt & Bux, which at the time was the technological and market leader in the production of commutators. Kautt & Bux invested in Kolektor and became an owner of 49 percent of the company. The investment proved very profitable for both partners. The Slovenian side got access to modern technology and expertise, and the German side got additional production facilities, skilled workers, and low-cost production, which increased its competitiveness on international markets.
BETA CONVERGENCE ANALYSIS OF GROSS VALUE ADDED IN THE HIGH-TECHNOLOGY MANUFACTURING INDUSTRIES
Authors: Șerban Andreea Claudia , Pelinescu Elena , Dospinescu Andrei Silviu
Published: December 2021

The paper examines the recent developments in the high-technology manufacturing sectors in the EU28 countries, focusing on the β-convergence of gross value added in the Manufacture of computers, electronic, and optical products, and the Manufacture of basic pharmaceutical products and pharmaceutical preparations. We employ two dynamic panel models estimated using the system of generalized method of moments (GMM) to address the risk of an endogeneity bias. The panel data analysis indicates a higher convergence for the Manufacture of computer, electronic, and optical products at 16.4% compared to 2.2% for the Manufacture of basic pharmaceutical products and pharmaceutical preparations, which is consistent with the existence of fewer barriers and higher exposure to competition in the case of the first analyzed sector. In the context of the role of the high-technology manufacturing industries as an engine of growth and the existing performance differences between the EU28 countries in terms of gross value added in the analyzed sectors, we investigated the β-convergence for two groupings EU15 and the new EU member states. We found that the new EU member states display a higher β-convergence rate than EU15, but also that they have a lower capital intensity. The result highlights the potential risk of some of the new EU member states becoming laggers in terms of the underlying factors behind gross value added as investment and labour force.
Cautionary Analysis of Spectral Radiance from Io’s Active Volcanoes Derived from Galileo Near-Infrared Mapping Spectrometer Data
Authors: Gerard Davies Ashley
Published: December 2021

Between 1996 and 2001, the Galileo Near-Infrared Mapping Spectrometer (NIMS) obtained 190 observations of the volcanic Jovian moon Io. Rathbun et al. (2018) [Astron. J., 156, 207] published a list of 287 measurements of 3.5 μm spectral radiance from some of Io’s active volcanoes, derived from a subset of the NIMS data. However, the spectral radiances reported by Rathbun et al. are lower, in some cases by multiple orders of magnitude, than other analyses of the same observations and spectral radiances derived from contemporaneous ground-based data. In many cases, the Rathbun et al. hot-spot radiances are underreported by a factor of π, likely due to a mistake in unit conversion. For a small number of powerful hot spots, additional discrepancies appear to be the result of poor fits to data limited in wavelength range by NIMS detector saturation and a methodology that discards short-wavelength NIMS data that otherwise would have provided more robust temperature model fits.
Polarization Study of Gamma-ray Binary Systems
Authors: Xingxing Hu , Jumpei Takata
Published: December 2021

The polarization of X-ray emission is a unique tool used to investigate the magnetic field structure around astrophysical objects. In this paper, we study the linear polarization of X-ray emissions from gamma-ray binary systems based on pulsar scenarios. We discuss synchrotron emission from pulsar wind particles accelerated by a standing shock. We explore three kinds of axisymmetric magnetic field structures: (i) toroidal magnetic fields, (ii) poloidal magnetic fields, and (iii) tangled magnetic fields. Because of the axisymmetric structure, the polarization angle of integrated emission is oriented along or perpendicular to the shock-cone axis projected on the sky and swings around 360° in one orbit. For the toroidal case, the polarization angle is always directed along the shock-cone axis and smoothly changes along the orbital phase. For the poloidal/tangled magnetic field, the direction of the polarization angle depends on the system parameters and orbital phase. In one orbit, the polarization degree for the toroidal case can reach the maximum value of the synchrotron radiation (∼70%), while the maximum polarization degree for poloidal/tangled field cases is several 10%. We apply our model to bright gamma-ray binary LS 5039 and make predictions for future observations. With the expected sensitivity of the Imaging X-ray Polarimetry Explorer, linear polarization can be detected by an observation of several days if the magnetic field is dominated by the toroidal magnetic field. If the magnetic field is dominated by the poloidal/tangled field, significant detection is expected with an observation longer than 10 days.
Characterizing the Observation Bias in Gravitational-wave Detections and Finding Structured Population Properties
Authors: Veske Doğa , Bartos Imre , Márka Zsuzsa , Márka Szabolcs
Published: December 2021

The observed distributions of the source properties from gravitational-wave (GW) detections are biased due to the selection effects and detection criteria in the detections, analogous to the Malmquist bias. In this work, this observation bias is investigated through its fundamental statistical and physical origins. An efficient semi-analytical formulation for its estimation is derived, which is as accurate as the standard method of numerical simulations, with only a millionth of the computational cost. Then, the estimated bias is used for unmodeled inferences on the binary black hole population. These inferences show additional structures, specifically two peaks in the joint mass distribution around binary masses ∼10 M
⊙ and ∼30 M
⊙. Example ready-to-use scripts and some produced data sets for this method are shared in an online repository.
Spin and Accretion Rate Dependence of Black Hole X-Ray Spectra
Authors: Kinch Brooks E. , Schnittman Jeremy D. , Noble Scott C. , Kallman Timothy R. , Krolik Julian H.
Published: December 2021

We present a survey of how the spectral features of black hole X-ray binary systems depend on spin, accretion rate, viewing angle, and Fe abundance when predicted on the basis of first-principles physical calculations. The power-law component hardens with increasing spin. The thermal component strengthens with increasing accretion rate. The Compton bump is enhanced by higher accretion rate and lower spin. The Fe Kα equivalent width grows sublinearly with Fe abundance. Strikingly, the Kα profile is more sensitive to accretion rate than to spin because its radial surface brightness profile is relatively flat, and higher accretion rate extends the production region to smaller radii. The overall radiative efficiency is at least 30%–100% greater than as predicted by the Novikov–Thorne model.
A new record of a rare labrid, Suezichthys notatus (Actinopterygii: Labridae), from Taiwan, with comparison to related species from Taiwan
Authors: Tang Chi-Ngai , Chen Hong-Ming , Ho Husan-Ching
Published: December 2021

Three specimens of a rare labrid, Suezichthys notatus (Kamohara, 1958) were recently collected from local markets, which were captured from deep-water off northern and southwestern Taiwan, and represent a new record for Taiwan. Suezichthys notatus can be distinguished from its congeners by a combination of characters: scale rows above lateral line 2½; low scaly sheath present at base of dorsal and anal fins; dorsal-fin element IX, 11; anal-fin elements III, 10; lateral line scales 25‒26, each with simple, unbranched laterosensory canal tube; cheek scale rows behind and below eye 2 and 2‒3 respectively; a group of prominent dark blotches extending from the interorbital region dorsoposteriorly; body depth at dorsal-fin origin 3.7‒3.9 in standard length; short pelvic fin without filamentous extension, 2.2‒2.5 in head length. Suezichthys resembles the labrid genus Pseudolabrus, comparison of Taiwanese species of Suezichthys with those of Pseudolabrus are given.
Graphological and semantic foregrounding as affecting gaze and speech of impulsive and reflective readers
Authors: Izmalkova Anna , Rzheshevskaya Anastasia
Published: December 2021

The study explores the effects of graphological and semantic foregrounding on speech and gaze behavior in textual information construal of subjects with higher and lower impulsivity. Eye movements of sixteen participants were recorded as they read drama texts with interdiscourse switching (semantic foregrounding), with features of typeface distinct from the surrounding text (graphological foregrounding). Discourse modification patterns were analyzed and processed in several steps: specification of participant/object/action/event/perspective modification, parametric annotation of participants’ discourse responses, contrastive analysis of modification parameter activity and parameter synchronized activity. Significant distinctions were found in eye movement parameters (gaze count and initial fixation duration) in subjects with higher and lower impulsivity when reading parts of text with graphical foregrounding. Impulsive subjects tended to visit the areas more often with longer initial fixations than reflective subjects, which is explained in terms of stimulus-driven attention, associated with bottom-up processes. However, these differences in gaze behavior did not result in pronounced distinctions in discourse responses, which were only slightly mediated by impulsivity/reflectivity.
The potential direct economic impact and private management costs of an invasive alien species: Xylella fastidiosa on Lebanese wine grapes
Authors: Frem Michel , Fucilli Vincenzo , Nigro Franco , El Moujabber Maroun , Abou Kubaa Raied , La Notte Pierfederico , Bozzo Francesco , Choueiri Elia
Published: December 2021

Since its outbreak in 2013 in Italy, the harmful bacterium Xylella fastidiosa has continued to spread throughout the Euro-Mediterranean basin and, more recently, in the Middle East region. Xylella fastidiosa subsp. fastidiosa is the causal agent of Pierce’s disease on grapevines. At present, this alien subspecies has not been reported in Lebanon but if this biological invader was to spread with no cost-effective and sustainable management, it would put Lebanese vineyards at a certain level of risk. In the absence of an Xylella fastidiosa subsp. fastidiosa outbreak, the gross revenue generated by Lebanese wine growers is estimated as close to US$22 million/year for an average period of 5 years (2015–2019). The potential quantitative economic impacts of an Xylella fastidiosa subsp. fastidiosa outbreak and particularly, the private control costs have not been assessed yet for this country as well as for others which Xylella fastidiosa may invade. Here, we have aimed to estimate the potential direct economic impact on growers’ livelihoods and provide the first estimate of the private management costs that a theoretical Xylella fastidiosa subsp. fastidiosa outbreak in Lebanon would involve. For this purpose, we used a Partial Budget approach at the farm gate. For the country as a whole, we estimated that a hypothetical full spread of Xylella fastidiosa subsp. fastidiosa on Lebanese wine grapes would lead to maximum potential gross revenue losses of almost US$ 11 million for an average recovery period of 4 years, to around US$ 82.44 million for an average grapevine life span period of 30 years in which infected plants are not replaced at all. The first yearly estimated additional management cost is US$853 per potentially infected hectare. For a recovery period of 4 years, the aggregate estimated additional cost would reach US$2374/ha, while the aggregate net change in profit would be US$-4046/ha. Furthermore, additional work will be needed to estimate the public costs of an Xylella fastidiosa subsp. fastidiosa outbreak in Lebanon. The observed costs in this study support the concerned policy makers and stakeholders to implement a set of reduction management options against Xylella fastidiosa subsp. fastidiosa at both national and wine growers’ levels. This re-emerging alien biota should not be neglected in this country. This understanding of the potential direct economic impact of Xylella fastidiosa subsp. fastidiosa and the private management costs can also benefit further larger-scale studies covering other potential infection areas and plant hosts.
Morphological and molecular evidence reveals three new species of Lithocarpus (Fagaceae) from Bidoup-Nui Ba National Park, Vietnam
Authors: Ngoc Nguyen Van , Binh Hoang Thi , Nagahama Ai , Tagane Shuichiro , Toyama Hironori , Matsuo Ayumi , Suyama Yoshihisa , Yahara Tetsukazu
Published: December 2021

Three new species, Lithocarpus bidoupensis Ngoc & Tagane, L. congtroiensis Ngoc & Yahara, and L. hongiaoensis Ngoc & Binh are described from Bidoup-Nui Ba National Park, Central Highland of Vietnam. Morphological analyses and Maximum likelihood tree based on genome-wide SNPs support the distinction of those species from the previously known taxa in the region. The three new species are considered to be endemic to the Bidoup-Nui Ba National Park and the preliminary conservation status for each species is evaluated as Critically Endangered.
Poplar box woodlands of Eastern Australia: an assessment of a threatened ecological community within the IVC framework
Authors: Hunter John T. , Addicott Eda
Published: December 2021

Aims: Ecosystems nationally at risk in Australia are listed under the Environmental Protection and Biodiversity Act (EPBC Act), and many cross State jurisdictional boundaries. The determination of these ecosystems across the State boundaries are based on expert knowledge. The International Vegetation Classification has the potential to be useful as a cross-jurisdictional hierarchy which also gives global perspective to ecosystems. Study Area: All bioregions that include Eucalyptus populnea as a dominant or major component of woodlands across the species known distribution. Methods: We use plot-based data (455 plots) from two states (Queensland and New South Wales) in eastern Australia and quantitative classification methods to assess the definition and description for the Poplar Box Woodland ecosystem type (hereafter “ecological community” or “community”) that is listed as endangered under the EPBC Act. Analyses were conducted using kR-CLUSTER methods to generate alliances. Within these alliances, analyses were undertaken to define associations using agglomerative hierarchical clustering and similarity profile testing (SIMPROF). We then explore how assigning this community into the IVC hierarchy may provide a mechanism for linking Australian communities, defined at the association and alliance levels, to international communities at risk. Results: We define three alliances and 23 associations based on the results of floristic analysis. Using the standard rule-set of the IVC system, we found that the IVC hierarchy was a useful instrument in correlating ecological communities across jurisdictional boundaries where different classification systems are used. It is potentially important in giving a broader understanding of communities that may be at risk continentally and globally. Conclusions: We conclude that the IVC hierarchy can incorporate Australian communities at the association level into useful units at higher levels, and provides a useful classification tool for Australian ecosystems.

Taxonomic reference: PlantNET (http://plantnet/10rbgsyd.nsw.gov.au/) [accessed June 2019].

Abbreviations: EPBC Act = Environmental Protection and Biodiversity Act; IVC = International Vegetation Classification; NMDS = non-metric multidimensional scaling; NSW = New South Wales; PCT = Plant Community Type; QLD = Queensland; RE = Regional Vegetation Community; SIMPER = similarity percentage analysis; SIMPROF = Similarity profile analysis.
The presence of simple renal cysts is associated with an increased risk of albuminuria in young adults
Authors: Boo Hyo Jin , Lee Jung Eun , Chung Son Mi , Jang Hye Ryoun , Huh Wooseong , Kim Dae Joong , Kim Yoon-Goo
Published: December 2021

Background/Aims: The prevalence of simple renal cysts increases with age; however, they are occasionally found in adults aged < 40 years. This cross-sectional study evaluated the clinical significance of simple cysts in young adults, focusing on their associations with hematuria and albuminuria.Methods: Adults aged < 40 years who underwent comprehensive medical examination between January 2005 and December 2013 were included. Simple renal cysts were identified by ultrasonography.Results: Renal cysts were found in 276 of the 5,832 subjects (4.7%). Subjects with medullary sponge kidney (n = 1) or polycystic kidney disease (n = 5) were excluded. A single cyst and multiple cysts were found in 234 (4.0%) and 42 (0.7%) subjects, respectively. Age, high systolic blood pressure, and history of hypertension were independent risk factors for the presence of simple cysts. Simple cysts were not associated with an increased prevalence of hematuria. However, subjects with cysts showed a higher prevalence of albuminuria than those without (11.3% vs. 4.5%, p < 0.001). Multivariate analysis revealed that the existence of simple renal cysts was associated with a 2.30-fold increased prevalence of albuminuria (95% confidence interval, 1.512 to 3.519; p < 0.001) independent of other risk factors.Conclusions: In young adults, the presence of simple renal cysts was independently associated with an increased prevalence of albuminuria. The causal relationship needs to be elucidated in further studies.
Using Backward Course Design to Create the Next Generation of Nurse Educator Leaders
Authors: White Anne , Maguire Mary Beth R.
Published: December 2021

The use of backward design is an effective strategy to create innovative and transformative programs. This article describes the use of backward design to create an effective graduate program to prepare nurse educators. Two cohorts of graduates provided feedback regarding program outcomes. Respondents were all working in an educator role after graduation, in both clinical and academic settings. Overall, respondents reported agreement in their ability to perform as effective educators in each of the eight National League for Nursing core competencies for nurse educators. This innovative use of backward design has proven effective in educating the next generation of nurse educators to be leaders in a digital world.

[
J Contin Educ Nurs
. 2021;52(12):554–557.]
Examining Whiteness in Obstetric and Pediatric Simulations: A Content Analysis
Authors: Lamberson Jessica , Pearson Pamela , Crooks Natasha , Ricca Paige
Published: December 2021

Background:

Whiteness is a systemic construct that functions to make itself invisible and prevent its racialization. Whiteness informs the nursing profession on all levels and impacts how nurses learn, relate to, and perpetuate whiteness through structural, curricular, interpersonal, and ideological means. The aim of this study was to use an antiracist framework to analyze manifestations of whiteness in select prelicensure obstetric and pediatric clinical simulation scenarios at a large midwestern college of nursing.

Methods:

Nine prelicensure nursing simulations were analyzed for themes using qualitative content analysis.

Results:

Two themes related to whiteness emerged from the data—normalizing whiteness in assessment and othering.

Conclusion:

Applying an antiracist framework in clinical nursing education can assist educators and students to see the embedded whiteness and racism in the curriculum and begin to address it. Additional analysis is needed to explore nurse educators and student perceptions of whiteness in simulations.

[
J Nurs Educ
. 2021;60(12):690–696.]
The role of miRNAs in the inflammatory phase of skin wound healing
Authors: Serra Federica ,   Department of Pharmacy, University “G. d'Annunzio” of Chieti-Pescara, Italy, Aielli Lisa , Costantini Erica ,   Department of Innovative Technologies in Medicine and Dentistry, University “G. d'Annunzio” of Chieti-Pescara, Italy,   Department of Medicine and Science of Aging, University “G. d'Annunzio” of Chieti-Pescara, Italy
Published: December 2021

Wound healing (WH) is a fundamental physiological process to keep the integrity of the skin, therefore impaired and chronic WH is a common and severe medical problem and represent one of the biggest challenges of public health. The resolution of the WH inflammatory phase is characterized by a complex series of events that involves many cellular types, especially neutrophils, macrophages and inflammatory mediators, which are crucial for a correct wound closure. MicroRNAs (miRNAs) play essential roles in wound repair. In fact, miR-142 is linked to inflammation modulating neutrophils' chemotaxis and polarization, while the polarization of M1 toward the M2 phenotype is driven by miR-223 and miR-132 is linked to chemokines and cytokines that activate endothelial cells and attract leukocytes and peripheral cells to the damage site. Thus, understanding the dysregulation of miRNAs in WH will be decisive for the development of new and more effective therapies for the management of chronic wounds.
Asymptotic and quenching behaviors of semilinear parabolic systems with singular nonlinearities
Authors: Wang Qi , Zhang Yanyan
Published: December 2021

In this paper, we consider a family of parabolic systems with singular nonlinearities. We study the classification of global existence and quenching of solutions according to parameters and initial data. Furthermore, the rate of the convergence of the global solutions to the minimal steady state is given. Due to the lack of variational characterization of the first eigenvalue to the linearized elliptic problem associated with our parabolic system, some new ideas and techniques are introduced.
On regularity and stability for a class of nonlocal evolution equations with nonlinear perturbations
Authors: Tran Dinh-Ke , Nguyen Nhu-Thang
Published: December 2021

We study a class of nonlocal partial differential equations with nonlinear perturbations, which is a general model for some equations arose from fluid dynamics. Our aim is to analyze some sufficient conditions ensuring the global solvability, regularity and stability of solutions. Our analysis is based on the theory of completely positive kernel functions, local estimates and a new Gronwall type inequality.
Radial symmetry of nonnegative solutions for nonlinear integral systems
Authors: Li Zhenjie , Zhou Chunqin
Published: December 2021

In this paper, we investigate the nonnegative solutions of the nonlinear singular integral system

   \begin{document}$ \begin{equation} \left\{ \begin{array}{lll} u_i(x) = \int_{\mathbb{R}^n}\frac{1}{|x-y|^{n-\alpha}|y|^{a_i}}f_i(u(y))dy,\quad x\in\mathbb{R}^n,\quad i = 1,2\cdots,m,\\ 0<\alpha<n,\quad u(x) = (u_1(x),\cdots,u_m(x)),\nonumber \end{array}\right. \end{equation} $\end{document}

where \begin{document}$ 0<a_i/2<\alpha $\end{document}, \begin{document}$ f_i(u) $\end{document}, \begin{document}$ 1\leq i\leq m $\end{document}, are real-valued functions, nonnegative and monotone nondecreasing with respect to the independent variables \begin{document}$ u_1 $\end{document}, \begin{document}$ u_2 $\end{document}, \begin{document}$ \cdots $\end{document}, \begin{document}$ u_m $\end{document}. By the method of moving planes in integral forms, we show that the nonnegative solution \begin{document}$ u = (u_1,u_2,\cdots,u_m) $\end{document} is radially symmetric when \begin{document}$ f_i $\end{document} satisfies some monotonicity condition.
Consolidation parameters in silts from varied rate CPTU tests
Authors: Bihs Annika ,   Department of Civil and Environmental Engineering, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway, Long Mike , Nordal Steinar , Paniagua Priscilla ,   School of Civil Engineering University College Dublin (UCD), Newstead Building Belfield, Dublin 4, Ireland,   Norwegian Geotechnical Institute (NGI), Trondheim, Norway
Published: December 2021

The interpretation of dissipation tests from cone penetration tests (CPTU) in silt is often considered challenging due to the occurrence of an unknown degree of partial consolidation during penetration which may influence the results significantly. The main objective of the present study is to investigate the influence of penetration rate and hence partial consolidation in silt deposits on the interpretation of consolidation parameters. Rate dependency studies have been carried out so as to give recommendations on how to establish design consolidation parameters in silts and consider the effect of partial consolidation on the development of design parameters. A comprehensive field and laboratory research program has been conducted on a silt deposit in Halsen-Stj?rdal, Norway. Alongside performing various rate penetration CPTU tests with rates varying between 0.5 mm/s and 200 mm/s, dissipation tests were executed to analyze the consolidation behaviour of the soil deposit. Furthermore, a series of soil samples have been taken at the site to carry out high quality laboratory tests. Correction methods developed for non-standard dissipation tests could be successfully applied to the silt deposit indicating partial consolidation. The results revealed an underestimation of the coefficient of consolidation if partial consolidation is neglected in the analysis, emphasizing the importance of considering the drainage conditions at a silt site thoroughly. To study the drainage conditions of a soil deposit a recently proposed approach has been applied introducing a normalized penetration rate to differentiate between drained and undrained behaviour during penetration. It is suggested that a normalized penetration rate of less than 0.1–0.2 indicate drained behaviour while a normalized penetration rate above 40–50 indicate undrained behaviour. Finally, available dissipation test data from a Norwegian Geo-Test Site (NGTS) in Halden, Norway have been used to successfully verify the recommendations made for silts.
The Economic Assessment of The Solution to the Multi-Criteria Problem for Determining Heavy Vehicles Usage Efficiency
Authors: Smirnov P. , Subbotin B. , Klimenko V.
Published: December 2021

The article discusses approaches to assessing the effectiveness of the use of heavy vehicles on the example of equipment for the transportation of bulk cargo. The modernization of the existing methods for assessing the effectiveness of its application and the choice of specific operating conditions in the presence of uncertainties and existing restrictions in the environment is pro-posed, a methodological approach to solving this problem based on the classical theory of linear programming is proposed. As a result, within the framework of the indicated practical problem, the range of optimal solutions for the value of the load-carrying capacity utilization factor has been determined. The modernization of the existing methods for assessing vehicles based on determining the efficiency of their operation, thus, can be recommended for use by the engineer-ing and technical personnel of motor transport enterprises.
The Scientific Communication Process in Homoeopathic Toxicology
Authors: Ramadhas G. , Sankar A.S. Suman , Sugathan N.V.
Published: December 2021

The present chapter evaluates the growth of literature of Toxicology in Homoeopathy. The Scopus database is used as source for the study. Data pertaining to toxicology in homoeopathy for the period 1963 to 2017 is retrieved and analyzed. The study reveals that toxicology literature grows rapidly in the later stages than in the earlier period. The United States of America is the leading contributors at the global level and India is in second position. Among the contributors, E.J. Calabrese, Professor of Toxicology, University of Massachusetts is the most prolific author for Toxicology in Homoeopathy literature. University of Kalyani and University of Massachusetts are the leading institutions, majority of the records are published in the journal ‘Homoeopathy', which is published from the USA and major contributions are in the subject domain ‘medicine' (65.4 per cent). Most frequently repeated keywords in toxicology of homoeopathy literature are: homoeopathy, humans, non-human, unclassified drug and animals.
Antioxidative Agents From Medicinal Plants
Authors: Kumar Sandeep , Hussain Ahmad , Sansi Manish Singh , Iram Daraksha , Priyanka  , Vats Ashutosh
Published: December 2021

The medicinal plants have been used by humans since ancient times, and the great civilizations of the world in ancient times were well aware of the benefits brought by the use of medicinal plants. This chapter provides important information regarding medicinal plants that have a wide variety of antioxidative agents ranging from bitter compounds that stimulate digestion system, phenolic compounds for antioxidant and numerous other pharmacological properties, antibacterial, and antifungal to tannins that act as natural antibiotics, diuretic substances, alkaloids, and so forth.
Probiotics as an Alternative Food Therapy
Authors: Bhandary Thejaswi , M Monisha , Vickraman Ilavarasan , K. A. Paari
Published: December 2021

Antibiotics have been responsible for the evolution of multidrug-resistant microbes. The side-effects of existing drugs and increased treatment costs have led to nutraceuticals gaining popularity. Nutraceuticals have therapeutic applications due to the ability of the probiotics to be viable in encapsulated pills and drinks. Due to their ability to exclude carcinogenic microorganisms by limiting the nutrients available and by competing for receptors nutraceuticals are useful against cancers. Nutraceuticals are useful against diabetes by controlling the genes involved in the insulin-signaling pathway. The future perspective for nutraceuticals includes an increase in production, reduction in manufacturing cost, and enhanced benefits.
Camel Colostrum Composition, Nutritional Value, and Nutraceuticals
Authors: Jrad Zeineb , Oussaief Olfa , Khorchani Touhami , El-Hatmi Halima
Published: December 2021

Colostrum is an important source of nutrients and immune factors for the newborn. The nutrient profile and immunological composition of colostrum vary from species to species. The composition and characteristics of the colostrum of human, cows, and goats have been the subject of several studies. The study of the characteristics of camel colostrum is more recent. In this chapter, the current understanding of the composition of camel colostrum (i.e., carbohydrates, proteins, oligosaccharides, fats, vitamins, and minerals) is reviewed. A complete comparison with other animal colostrum in whole composition and nutritional value of camel colostrum will be investigated in the current chapter. Consequently, the aim of this chapter is to provide an overview of the vast research, underlining the significance of camel colostrum in feeding of human beings and to predict the potential possible role of camel colostrum that can play in the functional products market in the future.
New Product Development and Regulatory Challenges in Nutraceutical Industry
Authors: Kumar Bhupendra , Singh Shivom , Srivastava Kajal , Wani Khursheed Ahmad
Published: December 2021

Functional food ingredients and dietary supplements are essential for health promotion and disease risk reduction. The demand for various food products is increasing day by day due to ever increasing population. Different multinational companies have invested to meet the demands of the people all over the world. However, some miscreants have adultered different food products that caused various concerns to the people and the government. Hence, different laws in different countries have been regulated to maintain the quality of food. However, there is major legislation and product approval challenges which should be aligned by global common regulations to move forward by reducing the scope for conflict between our regulatory approaches and by forging closer cooperation that can only be addressed by appropriate and accurate ingredients understanding, safety legislation, clinical studies benefits, advanced food processing technologies and various analytical studies. The nutraceutical revolution will direct us into a new era of medicine and health, in which the food industry will become a research oriented, analogous to the pharmaceutical industry. The present review article discusses the recent status of nutraceuticals and their importance to prevent various diseases.
Nutraceutical Intervention of Phytosterols in Cardiovascular Aging
Authors: Gupta Charu , Prakash Dhan , Gupta Sneh
Published: December 2021

Phytosterols and phytostanols are a large group of compounds that are found exclusively in plants. They are structurally and functionally related to cholesterol but differ from cholesterol in the structure of the side chain. Phytosterols lower total and low-density lipoprotein (LDL) blood cholesterol by preventing cholesterol absorption from the intestine, so they have been known as blood cholesterol-lowering agents. Phytosterols are naturally found in fruits, vegetables, nuts, and mainly oils. Dietary phytosterol intakes normally range from 160-400 mg/day with variations depending on food culture and major food sources. Dairy foods remain a food of choice for use as delivery vehicle for many functional ingredients including phytosterols and there are many dairy products available in the global markets which are enriched with phytosterols. The use of phytosterols in commonly consumed dairy products may soon provide an effective tool against CVD and its introduction to our food products is worth anticipating in the near future as nutraceuticals for healthy ageing.
Destination Governance
Authors: Belias Dimitrios , Rossidis Ioannis , Papademetriou Christos , Valeri Marco
Published: December 2021

The critical impact of the tourism sector on the development of local communities and economies has now been recognized, both theoretically and in practice, by local governments (OTAs) and other national or supranational policy makers. The OTAs, with their institutional role extending to the areas of shaping and promoting tourist destinations, are creating, in this direction, a network of synergies and actions with other stakeholders in the tourism sector. Therefore, the issue of collaborative marketing is major. At the same time, in addition to the strategy and management of the promotion and promotion of a tourist destination, there is a second level of vision of the action of OTA, that of the marketing facilitation strategy, which pursues the holistic coordinating the tourism sector of an area, ensuring the creation of synergies and the development of tourism development in the desired direction. For this reason, this chapter is going to examine the synergies created and how local authorities can contribute to this.
A Network-Based View on Extreme Expedition Team Composition in Alpine Tourism
Authors: Aalbers Hendrik Leendert , Spildooren Ramón
Published: December 2021

Conceptually drawing on network theory as its theoretical lens, this study examines two prime notions of network configuration of commercial expeditions. Exploring the role of both structural holes and network closure as indicators of team configuration for those venturing out in such extreme adventure, this study clarifies the impact of social structures, network closure, and structural holes in particular on performance outcomes in the context of expedition mountaineering. Presence and bridging of structural holes did turn out to be a significant predictor for the success or failure of an expedition. The findings show network closure to significantly influence the performance of mountaineering teams that make for a successful ascent. The capacity to span structural holes, commonly portrayed as serving as an eye-opener for options otherwise not found, does not appear to assist teams that make for successful ascents, however.
Cointegration and Causality Analysis of Portuguese Tourism and Air Quality
Authors: Madaleno Mara , Robaina Margarita , Eusébio Celeste , Carneiro Maria João , Rodrigues Vitor , Monteiro Alexandra , Gama Carla
Published: December 2021

This chapter aims to fill the knowledge gap regarding the relationship between tourism and air quality, specifically in the Portuguese tourism industry, with a focus on tourist nationality. It examines whether this relationship differs according to tourist origin. This study uses an air pollutant, PM10, with a strong impact on human health that has been highly neglected in the literature. Despite the great use of CO2 in assessing the causal relationship between tourism and the environment, this is not the best indicator of air quality (AQ). This chapter presents results by applying vector autoregressive models (VAR) with monthly data for the period of 2007-2017, considering the nationality of tourists that visit Portugal. Results suggest that PM10 levels and tourism are negatively correlated (in the Pearson sense) with a link between them in the long run. This relationship is confirmed by the four methodologies tested. The negative relation in Pearson and cointegration results suggests that tourism can be affected by AQ in Portugal and may lead to better AQ.
Profile of the Local Residents and Visitors of the Historical Villages of a Portugal Network
Authors: Natário Maria Manuela Santos , Santos Carlos , Melo Ana I. , Ferreira Augusta da Conceição Santos , Dias Dalila , Gomes Gonçalo , Azevedo Graça Maria do Carmo , Rocha Paula , Biscaia Ricardo , Duarte Ruben , Marques Rui Pedro
Published: December 2021

This chapter presents the results of the exploratory study regarding the profile of local residents and visitors of the Historical Villages of Portugal Network (nHVP). This network integrates 12 villages located in low density territories in the center of Portugal. It is important to conduct this study in order to conceive strategies and policies that will contribute to reversing the desertification tendency and to retaining resources and surpluses that would otherwise leave the region. The authors concluded that the local residents present a medium/high level of satisfaction in terms of the impact of tourism in their villages and also with the association of their village with the nHVP brand. However, the local residents' participation in the activities and touristic events is low, which is in part due to the high age of most local residents. Regarding the visitors of the nHVP, they are generally satisfied or very satisfied with several points. The lowest level of satisfaction relates to the public transportation, the communication networks, and the medical care available in the territory.
Legacy Economics and Meta-Management of Creativity in Destinations
Authors: Besana Angela , Vannini Maria Cristina
Published: December 2021

The concept of “Legacy” might have many interpretations, going from tangible to intangible, and accordingly, it can include a series of items that can be bequeathed to different kind of “heirs.” Either the giver or the community as main role players involved, the legacy is a bond for public administrations and destination managers. Legacy economics will be here connected to the innovative management of cultural destinations, where several and multi-goals-holders connect in order to provide resilience of villas, museums, and cultural assets together with increasing audiences and tourists. The collection of data about resilient creativity in Como (in the North of Italy) will show connections between legacy and management of public-private organizations for the last decade. A versatile and wide range of public and private interests together with national and international relevance will emerge. Community-type destinations will result as an original and innovative governance for resilience of culture and creativity connected with legacies and meta-management.