bluuebunny/crossref_metadata_2025 huggingface dataset:
TRANSIÇÃO DE ENERGIA E "DUE DILIGENCE" CORPORATIVA NO CONTEXTO DA COMPLEMENTARIDADE ENTRE OS DIREITOS HUMANOS E OS DIREITOS DA NATUREZA
Authors: Jiménez Guanipa Henry , Tous Javier
Published: July 2023

O artigo analisa como a emergência climática afeta não apenas os direitos humanos, mas também os direitos da natureza, tendo estes últimos como um sujeito autônomo e independente. Os direitos humanos e a natureza estão interligados e relacionados através da noção de integralidade. Esta noção é construída de duas maneiras: dos direitos humanos aos direitos da natureza e dos direitos da natureza aos direitos humanos. Diante da emergência climática, para proteger os direitos humanos e a natureza, a solução é reduzir as emissões de GEE, o que, segundo o consenso global de especialistas, só pode ser alcançado através da transição energética. Neste contexto, o artigo estabelece um princípio orientador: a transição energética não é simplesmente uma questão de substituir fontes de energia fóssil por fontes renováveis; a transição deve ser orientada pelo desenvolvimento sustentável, a proteção da natureza e o respeito aos direitos humanos. Assim, levando em conta que os projetos de transição de energia são principalmente liderados e implementados por empresas, um elemento chave que deve orientá-la é a due diligence corporativa sobre os direitos humanos, que, em virtude da integralidade dos direitos humanos, devem estar interligados com a proteção da natureza (due diligence da natureza) e a luta contra emergências climáticas (climate due diligence).
NACIONALIDADE COMO FATOR (DES)INTEGRADOR:
Authors: D ́Ávila Lopes Ana Maria , Pereira dos Santos Junior Luis Haroldo , Cavalcante Barreto Midred
Published: July 2023

Com base em pesquisa bibliográfica e jurisprudencial, o presente trabalho objetivou examinar de que maneira o fortalecimento do Estado de Direito na Bósnia e Herzegovina pode contornar problemas como a ausência de participação popular na elaboração da própria constituição. A despeito da fragilidade institucional e do acirrado conflito interétnico, a viabilização de uma cultura democrática mostra-se como uma alternativa viável para o desenvolvimento de um espaço comunicativo que permita a construção de um quadro normativo destinado a garantir os direitos humanos de todos e a consequente convivência da diversidade
FLAWS OF GLOBAL HEALTH GOVERNANCE AS ILLUSTRATED BY THE COVID-19 VACCINE DISTRIBUTION
Authors: Mohamadhossen Aziza , Parola Giulia
Published: July 2023

Global cooperation during times of crisis is necessary to procure effective responses and to uphold the universal human right to health. However, the COVID-19 pandemic has highlighted weaknesses within global health governance, particularly relating to the COVAX program and vaccine distributions. This paper sets out to describe and critically analyze the flaws within these frameworks. A narrative literature review was conducted to gather a widespread of information about weaknesses of the COVAX program. Additionally, the contrasting realities within Brazil and Canada were described to illustrate the differences between the two nations. The primary themes extracted from literature included a shift to multilateralism, nationalism, and protectionism. Furthermore, fragmentation within international institutional frameworks and their power distribution created grey-areas and impeded effective responses. This paper suggests measures to reinforce the authority of global health governance, including revisiting response policies, incentivizing global cooperation, and encouraging nations to recommit to global cooperation.
Options of radiological methods in diagnostics of gastroenterological diseases
Authors: Lemeshko Z. A.
Published: July 2023

The aim of review. To analyze reports and publications devoted to radiological methods in gastroenterology and to present options of these methods to doctors: gastroenterologists, experts in radiology and doctors of other specialties. Key points. Results of scientific development and applications of radiological methods in diagnostics of gastrointestinal diseases in clinical practice are presented. The further improvement of diagnostic techniques is required. High correlation rate of radiological to clinical and morphological data is demonstrated. Radiological methods are highly effective in different fields of clinical practice, including gastroenterology, pediatrics, oncology, surgery, transplantology etc. Conclusion. The range of issues that can be solved by modern radiological methods of diagnostics became broader.
Hematological manifestations of autoimmune gastritis
Authors: Losik Ye. A. , Ivashkin V. T.
Published: July 2023

Aim of investigation. To estimate hematological disorders in patients with high titer of anti-parietal cell antibodies (APCA). Material and methods. Overall 71 patient with high serum APCA titer were included in original study. At all patients scores of clinical and biochemical blood tests were investigated. The special attention was given to RBC color index (CI), mean corpuscular volume (MCV), mean hemoglobin content per cell and serum iron and vitamin В12 concentration. Results. The mean indices of clinical and biochemical blood tests in APCA-positive patients were within normal range. Hematological changes were revealed in 25,4% of patients. In 11,3% of the cases either macrocytic or microcytic anemia was diagnosed. Increase in mean corpuscular volume and serum cobalamin level were found out in 16,9% of the cases, while low hemoglobin level - only at 25% of them. No Helicobacter pylori infection has been revealed in the patients with macrocytic anemia, however no significant difference on its prevalence in patients with different serum cobalamin level was found out. Conclusion. The majority of cases with high APCA titer has no hematological signs of autoimmune gastritis. In 25,4% of patients with APCA changes in common blood count were revealed, most often - of MCV and the CI. Anemia was diagnosed in 11,3% of patients. In investigated group cobalamin deficiency was found in 16,9% of patients, iron deficiency - in 9,9% of the cases. In 75% of patients increase in MCV was the only sign of cobalamin deficiency. Iron deficiency was more common in women.
Probiotics, metabolism and the functional condition of cardio-vascular system
Authors: Kashukh Ye. A. , Ivashkin V. T.
Published: July 2023

The aim of review. To characterize possible relation between microbiome and cardio-vascular system structural and functional state. Key points. Along with traditional concepts on the risk factors of atherosclerosis and cardio-vascular diseases development one should take into account data on the new pathogenic mechanisms for these diseases. According to recent studies human gastrointestinal microbiome may increase cardiovascular risk due to bacterial production of proinflammatory proteins that both promote development of atherosclerosis and directly affect the heart and vessels. Probiotics, that are mainly prescribed at gastroenterological diseases, may be applied for correction of cardiovascular risk factors as well. Obtained data demonstrate that intake of certain probiotic strains may be applied as a successful treatment of atherosclerosis, systemic hypertension, metabolic syndrome and heart failure. Conclusion. Microbiome may be involved in development of cardio-vascular diseases and atherosclerosis due to metabolic symbiosis with the host. Probiotics may be applied as preventive medication for correction of metabolic disorders that result in development of cardio-vascular diseases and atherosclerosis.
The short-term and long-term results of three-stage surgical treatment of ulcerative colitis with formation of ileal J-pouch
Authors: Tsarkov P. V. , Kravchenko A. Yu. , Tulina I. A. , Kitsenko Yury Ye.
Published: July 2023

Aim of investigation. To estimate results of three- stage treatment approach in severe ulcerative colitis aimed for resection of affected colon and restoration of intestinal continuity. Material and methods. Overall 22 patients were treated according to the three-stage mode, of them 20 were operated urgently due to development of acute complications. The average duration of conservative treatment was 32,8±42,5 months. All patients at the first stage underwent operations related to the emergency state, at the second stage - reconstructive surgery with formation of the ileal J-pouch followed by closure of ileostoma. Results. Patients, who underwent the first stage of treatment on the basis of our institution, had shorter time of surgical treatment, as compared to the cases when colectomy was performed in the other clinics: 4,7±1,6 and 46,1±39,8 months respectively (p=0,02). The average work capacity recovery after surgical treatment was 4±2 months. Stool frequency was 6,1±2,45 times per day, every fifth patient had nighttime defecation; 19 of 21 patients could distinguish type of their reservoir contents and were able to provide its retention. Pouchitis was observed in 21% of cases. The pouch malfunction requiring its resection occurred in 4%. Conclusions. The three-stage surgery for ulcerative colitis is an optimum management approach in the presence of complicated ulcerative colitis. It allows to carry out colonic resection with the lowest risk of morbidity, to create the intestinal reservoir , to provide social professional rehabilitation of patients and to reduce postoperative complications rate significantly. Key words: ulcerative colitis, ileal pouch, colectomy, proctectomy, laparoscopy
Options of biological substances application in rectal fistulas treatment (Review of the literature)
Authors: Kuzminov A. M. , Frolov S. A. , Vyshegorodtsev D. V. , Korolik V. Yu. , Minbayev Sh. T. , Bogormistrov I. S. , Chernozhukova M. O.
Published: July 2023

Aim of review. To present literature data of the treatment of incomplete rectal fistulas with application of biological substances. Summary. Treatment of rectal fistulas remains burning issue in coloproctology due to unsatisfactory results of surgery resulting in high relapse rate, usually regardless of applied surgical method and high risk of severe complications as anal sphincter incompetence. This is why development of sparing methods of rectal fistula treatment that will allow to decrease intraoperative trauma of the anal sphincter at minimal risk of disease recurrence and, therefore, to prevent development of sphincter incompetence is important. Application of biological materials in rectal fistulas treatment result in reduction of the wound size, accelerates reparative processes and decreases degree of traumatization. Minimization of surgical impact on the anal sphincter allows repetitive application of biological materials up to the achievement of positive effect. Conclusion. Application of biological materials at sphincter-preserving technique provides decreased risk of development of postoperative anal sphincter incompetence.
Viabilidad de una firma consultora y asesora de gestión de proyectos por medio del uso de herramientas del PMBOK para los municipios de Colombia
Authors: Diaz Molina Angela María , Sastoque Forero María Angelica
Published: July 2023

En el presente artículo se da a conocer la propuesta de investigación, la cual se fundamenta en la inexistencia de un estudio de viabilidad que soporte la creación de una firma consultora de asesoría de gestión de proyectos, para los municipios de Colombia. El objetivo general de la propuesta de investigación es desarrollar un estudio de viabilidad para la firma de consultoría de gestión de proyectos, por medio de las herramientas técnicas del PMBOK; lo anterior, en pro de la determinación de la rentabilidad de la firma de consultoría y asesoría en gestión de proyectos, con la que se busca operar en todos los municipios de Colombia. En razón a ello, se plantean tres objetivos específicos que contribuyen de forma directa al cumplimiento del objetivo general. El desarrollo de la propuesta de investigación permitirá conocer el perfil de la empresa de consultoría y las necesidades en cuanto a gestión de proyectos en los municipios, finalmente, identificar la viabilidad del proyecto. Para esto se ha realizado un recorrido teórico que de fundamento a la propuesta de investigación.
Fortalecimiento organizacional de proyectos de turismo rural en Cundinamarca, Colombia
Authors: Valderrama Fernández Jonny Mauricio , Quesada Barragá Naryi Xiomara , Garzón Ávila Yon
Published: July 2023

Colombia es un país donde constantemente se genera una empresa, sin embargo muchas de estas nuevas empresas no superan los tres años antes de cerrar, es por ello que este documento busca desarrollar proyectos de fortalecimiento organizacional enfocados en la empresa ecoturística y sus variables, es allí donde se contenido técnico, científico y académico orientado al fortalecimiento comunitario rural de los municipios, con un proceso organizativo que promueva la gestión de proyectos de turismo rural. En base al trabajo desarrollado se evidencia que las empresas de turismo rural brindan experiencias de intercambio cultural y de sensibilización ambiental donde a través del trabajo desarrollado se logra la visibilización de las veredas y fincas para hacerlas atractivas para el turismo, además de integrar a la comunidad. lograr un trabajo conjunto donde las personas puedan generar ganancias en el desarrollo de su trabajo.
Diseño de herramientas financieras para el desarrollo personal y empresarial de la mujer rural agremiada en el municipio de La Plata Huila
Authors: Durán Espinosa Martha Cecilia , Chávez Ossa Luis Arnulfo , Torres Leguizamo Melisa
Published: July 2023

Se realiza esta propuesta especialmente para la mujer rural agremiada del Municipio de La Plata Huila, con el fin de concientizar a esta población en sus facultades, crear espacios para desarrollar sus habilidades en educación, que contribuyan a una mejora como integrantes de un hogar, una comunidad y una región. Con el objetivo de tener en cuenta las diversas necesidades por las que atraviesan. La investigación es de enfoque cuantitativo, de tipo descriptivo, la técnica para la recolección de información se realiza mediante la aplicación de un cuestionario con preguntas cerradas. Estos resultados serán analizados para diseñar un programa de educación básica financiera. El instrumento propuesto para el desarrollo de esta investigación permite obtener información sobre variables sociodemográficas, los conocimientos financieros de la población objetivo, en conceptos de ahorro, presupuesto, inversión y endeudamiento. Con esta investigación, se busca crear una herramienta de educación virtual, donde se pueda acceder a información básica financiera para que desempeñen desde su hogar y empresa agropecuaria, un papel en el área económica, para la toma de decisiones personales y empresariales y así planear, organizar, administrar, financiar, ahorrar, emprender y lo más importante mejorar su calidad de vida y la de las personas que están en su entorno.
Plan estratégico y prospectivo de la procesadora de alimentos lácteos Marquezlac del municipio de Ciénaga Boyacá a 2026
Authors: Ubaque Camacho Pedro Emilio , Vanegas Florez Oswaldo
Published: July 2023

El presente documento es producto de la propuesta formulación del plan estratégico y prospectivo de la Procesadora de Alimentos lácteos MARQUEZLAC para el año 2026, la cual se encuentra ubicada en el municipio de Ciénaga, Departamento de Boyacá, a partir de la aplicación del modelo avanzado de la prospectiva estratégica, que comprende el desarrollo de las siguientes fases: estado del arte y vigilancia tecnológica del sector lácteo; identificación de los factores de cambio y análisis estructural basado en el método MICMAC, análisis de juego de actores MACTOR, diseño de escenarios según la metodología de cruz de ejes de Peter Schwartz, formulación de estrategias y planes de acción (Mojica, 2008). La necesidad primordial que fundamenta el desarrollo del plan estratégico prospectivo consiste en que actualmente la Procesadora de Alimentos Lácteos MARQUEZLAC no cuenta con un direccionamiento estratégico claro; así como, el potencial de crecimiento del sector lácteo en la provincia de Márquez, le genera retos y oportunidades a la empresa, los cuales deben ser capitalizados oportunamente mediante una planeación estratégica visionaria y clara. La metodología utilizada en el desarrollo de la propuesta se basa en un enfoque mixto de investigación, por cuanto se aplicará el método Delphi para la consulta de expertos; al igual que los métodos MICMAC y MACTOR de la caja de herramientas de la prospectiva estratégica propuestos por Michel Godet (2007).
“Still Watching Cartoons?” Infantilization of Young Anime Fans in India: A Critical Discourse Analysis
Authors: Chandi Jasdeep Kaur , Trehan Kulveen
Published: July 2023

Animated content is primarily included in the children’s shows category in India. As a result, young adult and adult Indian anime fans are affected by this categorization. To explore their sociocultural experiences in Indian society, fan responses to three questions – posted on Quora, an online question and answer (Q&A) platform – were critically analyzed using Fairclough’s three-dimensional model of Critical Discourse Analysis. The three Quora questions selected for the study were What is it like being an anime fan in India? What is it like to be a manga and anime lover in India? And, why most of the people in India think that anime is for kids? The analysis revealed infantilization of Indian anime fans, mostly young adults or adults. Findings disclosed marginalization of and discrimination against Indian anime fans by the conservative older generation who look at any East Asian popular media from a racially biased lens. Invisibilization, mystification and stereotyping marked the discourse on Indian female anime fans who may not participate extensively in the male-dominated anime fan community on the online fora but consume anime by subversion and negotiated readings.
The “Innocent” Other: Hollywood’s Post 9/11 Muslim Child and Childhood
Authors: Eddarif Hajar
Published: July 2023

The present article interrogates the ways in which Hollywood cinema articulates the exclusion of the Muslim child from popular discourses of childhood and how such exclusion continues to condition the cultural identity of children and most importantly how it defines the notion of childhood. This paper opts for a textual and discursive analysis of Hollywood’s post-9/11 film through a cultural and postcolonial studies’ lens. The main purpose behind this is to scrutinize Hollywood’s cultural conceptualization of children, how it represents different childhoods, in what way it categorizes children and who is perceived as a child.
Language, Culture, and Indigeneity: Reflections on their Interplay
Authors: Davis Robert , Sanatullova-Allison Elvira
Published: July 2023

Language encultures the speaker as subject and provides access to an identity that is grounded in frames of knowing and being. This paper gives an overview of Indigeneity in relation to language and culture from four different pathways: 1) language and self-preservation, 2) nonviolent means to communal well-being, 3) student narratives and agency, and 4) the forward gaze of conceptions of “abode” and “sojourn.” A reflection on the value of Indigenous ways of knowing, remembering, and performing in Native culture, as well as in the dominant, broader society, intersect in these pages.
Communities of practice in tourism SMES of the department of Caldas – Colombia
Authors: Marulanda Carlos , Castellanos Galeano José Fernando , Valencia Duque Francisco Javier
Published: July 2023

Within the framework of knowledge management, it is necessary to develop intellectual capital, for which variables such as communities of practice must be considered, given their importance for the development of organizations. The research results presented in this article are intended to establish the state of development of communities of practice related to intellectual capital in SMEs in the tourism sector of the Department of Caldas, Colombia, for which it was used a descriptive and correlational analysis with an evaluation model adapted to specific communities, it was possible to evaluate 87% of the SMEs. The main findings show the consolidation of communities of practice of SMEs operators in the tourism sector in the department of Caldas, and highlight the leadership and teamwork of these.
Microproteins - discovery, structure and function
Authors: Mohsen Jessica , Martel Alina , Slavoff Sarah
Published: July 2023

Advances in proteogenomic technologies have revealed hundreds to
thousands of translated small open reading frames (sORFs) that encode
microproteins in genomes across evolutionary space. While many
microproteins have now been shown to play critical roles in biology and
human disease, a majority of recently identified microproteins have
little or no experimental evidence regarding their functionality.
Computational tools have some limitations for analysis of short, poorly
conserved microprotein sequences, so additional tools are needed to
determine the role of each member of this recently discovered
polypeptide class. A currently underexplored avenue in the study of
microproteins is structure prediction and determination, which delivers
a depth of functional information. In this review, we provide a brief
overview of microprotein discovery methods, then examine examples of
microprotein structures (and, conversely, intrinsic disorder) that have
been experimentally determined using crystallography, cryo-electron
microscopy, and NMR, which provide insight into their molecular
functions and mechanisms. Additionally, we discuss examples of predicted
microprotein structures that have provided insight or context regarding
their function. Analysis of microprotein structure at the angstrom
level, and confirmation of predicted structures, therefore, has
potential to identify translated microproteins that are of biological
importance and to provide molecular mechanism for their in vivo roles.
Multidimensional screening for a multifunctional cervix: Examining cervical gland area at cervical length screening to predict spontaneous preterm birth.
Authors: Meyer Jessica A. , Limaye Meghana , MPH Ashley S. ROMAN, MD, , Brubaker Sara , Mehta-Lee Shilpi
Published: July 2023

OBJECTIVE: To sonographically characterize the cervical gland
area (CGA) and determine if its evaluation at the time of cervical
length (CL) screening can be useful for preterm birth (PTB) prediction.
DESIGN: Pilot retrospective cohort study. SETTING:
Academic medical center (NYU Langone Health Tisch Hospital).
POPULATION: Singleton gestations with universal CL screening
performed between 18 – 23
weeks with subsequent live neonate delivery. METHODS:
Transvaginal ultrasound (TVUS) cervical images and clinical data were
reviewed, comparing sonographically present and absent CGA groups.
MAIN OUTCOME MEASURES: Spontaneous PTB <37 weeks and
quantitative CGA measurements. RESULTS: The cohort of 772
patients demonstrated similar characteristics when stratified by absent
and present CGA. Rates of PTB and absent CGA were 2.6% and 2.3%,
respectively. Absent CGA was significantly associated with delivery
<37, <34, and <32 weeks
(p<0.001), but gland measurements did not correlate with
gestational age at delivery. There was good agreement between reviewers
for qualitative CGA (PABAK 0.89). Multiple logistic regression modeling
demonstrated better performance of CL screening for PTB prediction with
the addition of qualitative CGA evaluation (p<0.001).
CONCLUSIONS: Qualitative evaluation of the CGA on mid-gestation
TVUS may improve CL screening for PTB. Given the biologic activity of
the cervical glands, optimal screening in populations with various risk
profiles may warrant a multimodal approach that evaluates the mechanical
and biological functions of the cervix.
The Impact of an Online Job Fair: Experimental Evidence from Bangladesh
Authors: Matsuda Norihiko , Hayashi Ryotaro
Published: July 2023

This study examines the impact of an online fair for information and communication technology jobs in Bangladesh. The study found that there was no effect on employment probability since more than 90% of job offers generated were rejected. Jobseekers learned about market conditions at the fair. This led jobseekers to lower their labor market expectations and reservation wages. As a result, jobseekers who had been employed kept their jobs longer even if jobs did not match their skills. Those initially unemployed ended up with lower employment probabilities and lower skill-match quality.
Ecological Protection in the People’s Republic of China: Pilot Case Studies on Comprehensive Eco-Compensation, Poverty Alleviation, and Green Development
Authors: Shion Yee Au , Cardascia Silvia , Cai Xueliang
Published: July 2023

The working paper provides county-level case studies of ecological compensation in the People’s Republic of China (PRC). Eco-compensation has become an important policy framework in the PRC, involving a wide range of programs that promote conservation and environmental restoration while supporting local livelihoods and poverty alleviation. It uses a package of incentive-based policies and regulatory instruments to tackle environmental issues such as water pollution, biodiversity loss, land degradation, or deforestation. The PRC’s experience can offer useful insights to other countries facing similar challenges in environmental management.
Germination of seeds of Dianthus plumarius L. (Caryophyllaceae Juss.) after storage period of 43 and 44 years
Authors:   University of Forestry, Sofia, Bulgaria, Marinova Mariela
Published: July 2023

The seed germination tests of long-term (1978- and 1979-year harvest) storage seeds of Dianthus plumarius were carried out. The seeds were stored in a cold chamber (0-5 °C) for 43- and 44-year period, respectively, in the hermetically sealed glass containers. The experiment was conducted in laboratory conditions, on filter-paper, in three consequent stages: initial screening (Sept/Oct. 2022, sample 1978); 6 seed samples of 100 seeds each: 3 samples from 1978 and 3 samples from 1979 year (Oct/Nov. 2022) and 12 x 100 seeds with the highest germination taken from the previous experimental batch (Nov/Dec.2022). The temperature and air humidity were monitored daily by an Electronic Temperature station. The results from trials Oct./Nov.2022 showed that the highest germination energy (GE) was found in the seed sample from 1978 (65%) while the GE varied between 42 and 46% in the samples of the 1979’ harvest. The maximum percentage of germination, in almost all experimental samples, was achieved on the 14th day and until the end of the experiment remained unchanged. The highest percentage of germination was found in sample from 1978 year - 82%. A statistically significant difference was observed between samples from 1978 and the two samples from 1979 (p≤0.05, ANOVA). The germination process took place at relatively low temperatures and at a relatively small day-night amplitude. The two consecutive experiments confirmed the fact that the seed samples from 1978 year showed a higher germination energy, which could be explained by a higher water content in the seeds which were initially placed in cold storage and were preserved during the storage conditions for the specified long-term period. The high germination rates observed in the present experiment encourages further investigations.
Effect of combined application of herbicides and foliar fertilizers on growth, development and yield of Knezha 509 maize hybrid
Authors:   Maize Research Institute, Knezha, Bulgaria, Goranovska Sonya
Published: July 2023

In 2020 and 2021, a block trial was conducted with two herbicide preparations and four foliar feeding products for maize. The studies were carried out with maize, hybrid Knezha 509, grown under non-irrigated conditions after a wheat predecessor. The effect of the combined application of the herbicide preparations Stomp new 330 EK and Hemniko 24 SK and of the foliar microelement fertilizers for maize, Amalgerol, Vertex high N-34 and Foliar extra was studied. The influence of the studied treatment systems on maize height and grain yield was established. For the conditions of the experiment, the plants treated with a tank mixture of Hemniko 24 SC at a dose of 21 ml/da and Amalgerol at a dose of 500 ml/da had the highest height. The increase compared to economic control is 6.46% (for 2020) and 7.3% (for 2021). The highest grain yield (average for the study period) – 643.9 kg/da was obtained from the same variant of the experiment, and the increase compared to the economic control was 12.91%.
Changes in water relations, leaf gas exchange and elemental composition of peach leaves infected with Taphrina deformans (Berk.) Tul
Authors:   Agricultural University-Plovdiv, Bulgaria, Piperkova Neshka
Published: July 2023

An investigation of water relations, leaf gas-exchange and elemental composition of healthy (control) and naturally infected with Taphrina deformans peach leaves was carried out. It was established that the water content and water potential were significantly higher in the infected leaves, while the relative water content and transpiration rate were not changed. The dark period respiration rate of infected leaves increased dramatically but the gross photosynthesis rate was strongly inhibited. The phosphorus and potassium content of infected leaves was higher than in the healthy leaves, but the content of other analysed elements diminished at different extent. The current work presents the results of the study related to the changes in water status, CO2 exchange rate and elemental composition of T. deformans-infected peach leaves.
First report of the occurrence of Pestalotiopsis sp. on blueberry in Bulgaria – morphology and pathogenicity - (short communication)
Authors:   Agricultural University-Plovdiv, Bulgaria, Piperkova Neshka
Published: July 2023

The cultivation of blueberry (Vaccinium sp.) in Bulgaria has increased in recent years, but the knowledge of its diseases is almost nonexistent. During monitoring for the sanitary status of blueberry crops in Southern Bulgaria (Plovdiv region), symptoms of stem cancer, twigs necrotic lesions, leaf spots and low vigour were observed on 3-year-old Duke cv. Four isolates were obtained from damaged stems and leaves and were single-spored. The isolates were recognized as Pestalotiopsis sp. according to the cultural characteristics of the fungal colony (colony color and the presence of fruiting bodies) and morphological characteristics of conidia (color, length, width, number and size of the apical and basal appendages). In a controlled experiment, the representative isolate was pathogenic to the Duke cv. Based on morphological characteristics and pathogenicity, this study is the first report of the Pestalotiopsis sp. associated with cancer stem and leaf spots on blueberries in Bulgaria.
HL-A27 and W10 in Reiter's syndrome and nonspecific urethritis
Authors: Harris JR , Gelsthrope K , Doughty RW , Lee D , Morton RS.
Published: July 2023

By means of a standard lymphocyte microcytoxic technique, the tissue types were fully determined in 41 patients with non-gonococcal urethritis and 25 patients with Reiter's syndrome. The antigen HL-A27 was identified in 14 of the patients with Reiter's syndrome and occurred in 3 of the patients with non-gonococcal urethritis. An excess of the genotype HL-A27/W10 was found in patients with Reiter's syndrome. There was no correlation between the duration or the severity
Lymphocyte transformation, IgE and T-cells in eczema vaccinatum treated with transfer factor. A case report
Authors: Dahl B , Thestrup-Pedersen K , Ellegaard J , Zachariae H.
Published: July 2023

Transfer factor (TF) was given to intensify the cell-mediated immune reactions in an atopic patient with generalized vaccinia. The patient showed marked reactivity of peripheral blood lymphocytes to stimulation with phytohaemagglutinin and pokeweed mitogen, but also in nonstimulated cultures. However, later tests with mitogen stimulation of lymphocytes indicated a defective cellular defence mechanism. The addition of autologous plasma to lymphocyte cultures depressed the reactivity of PHA-stimulation considerably. Initially, the patient also showed a normal T-lymphocyte count in peripheral blood, but six months after her vaccinia, extremely high serum IgE levels and a decreased percentage of T-lymphocytes was observed. Although an evaluation of the clinical effect of transfer factor injection is difficult, it should be noted that the patient's temperature immediately fell to normal, and her general health improved following treatment.
Epidermal intercellular binding of concanavalin a and pemphigus antibody
Authors: Nishikawa T , Harada T , Hatano H , Ogawa H , Taneda A , Miyazaki H.
Published: July 2023

The binding sites of Concanavalin A (Con A) and pemphigus antibody in the intercellular spaces of the human epidermis have been investigated. Extraction of human skin with phosphate-buffered saline (PBS) and 70% ethanol resulted in complete loss of the binding sites of the pemphigus antibody, whereas the extracted skin still retained its reactivity to Con A. Preincubation with more than 0.25 mg/ml of Con A with normal skin caused a reduction in the binding of pemphigus sera. However, preincubation of pemphigus sera with human skin caused no inhibition of the subsequent binding of fluorescein-labelled Con A. These results indicate that Con A binding sites might be related to, but not identical with those of pemphigus antibody.
Ultrastructure of freeze-cleaved stratum basale and stratum Malpighii
Authors: Hashimoto K.
Published: July 2023

Abstract is not availeble.
Incidence of circulating antibodies reactive with basal cells of skin in drug reactions
Authors: Van Joost T.
Published: July 2023

Abstract is not availeble.
Chronic mucocutaneous candidiasis, dermatophytosis and defective cellular immunity in monozygotic twins
Authors: Mobacken H , Lindholm L.
Published: July 2023

Abstract is not availeble.
Release of nickel from silver coins
Authors: Pedersen NB , Fregert S , Brodelius P , Gruvberger B.
Published: July 2023

Abstract is not availeble.
Liver biopsy in psoriatics previously treated with potassium arsenite. A controlled study
Authors: Zachariae H , Sogaard H , Nyfors A.
Published: July 2023

Abstract is not availeble.
Early insulin response to glucose injected intravenously in patients with localized granuloma annulare
Authors: Blohmé G , Mobacken H , Waldenström J.
Published: July 2023

Abstract is not availeble.
Collagenolytic activity in rheumatoid nodules. I. Effect on acid-soluble tropocollagen
Authors: Dabbous MK , Yamanishi Y , Maeyens E , Hashimoto K , Hardison H.
Published: July 2023

Abstract is not availeble.
Studies on guinea pig skin cell cultures. 3. Minimum cell numbers for establishment
Authors: Regnier M , Prunieras M.
Published: July 2023

Abstract is not availeble.
Ultrastructure of necrobiosis lipoidica diabeticorum
Authors: Kobayasi T , Danielsen L , Asboe-Hansen G.
Published: July 2023

Abstract is not availeble.
Keratosis punctata palmaris et plantaris. A morphological study on the relation to the epidermal sweat duct unit
Authors: Tezuka T.
Published: July 2023

The palmar and plantar pits of keratosis punctata palmaris et plantaris were examined histologically in both vertical and horizontal sections. Pits were located in the crista superficialis epidermis, especially in the orifice of the sweat duct, but no iodine-starch reaction was detected in pits by perspiration testing. In the center of a pit was a parakeratotic wedge, deflecting the squamous cell layers downwards. The sweat duct was found in this parakeratotic wedge, and was occasionally obstructed.
Acral arteriovenous tumor
Authors: Carapeto FJ , Garcia-Perez A , Winkelmann RK.
Published: July 2023

A unique, superficial, lobulated, benign vascular tumor of the skin, found in the acral areas of adult males, is described. The combination of three different elements--arterial, venous, and transitional vascular channels--make up the predominant histologic features of this tumor. The transition of fibromuscular channels indicates a venous lesion, but the acral location of the lesions and the structure and staining characteristics suggest that the lesion is a hamartomatous proliferation of the Sucquet-Hoyer canal of the true glomus.
Degradation of dermal fibrillar structures: effects of collagenase, elastase, dithioerythritol and citrate
Authors: Kobayasi T , Hentzer B , Asboe-Hansen G.
Published: July 2023

Clostridial collagenase, elastase, medium material of human skin culture, dithioerythritol and citrate buffer, pH 3.5, were applied to fresh human skin specimens. Phenomena of degradation of dermal fibrils were observed by electron microscopy.
Epidermolysis bullosa acquisita and Crohn's disease
Authors: Livden JK , Nilsen R , Thunold S , Schjønsby H
Published: July 2023

A patient with epidermolysis bullosa acquisita (EBA) associated with Crohn's disease is presented. The clinical, histological and immunological findings were in keeping with previous reports. However, clinically normal skin and mucosa exhibited deposits of IgG and C3 in the basement-membrane zone. These deposits remained unchanged during the treatment period. It is therefore suggested that immunological mechanisms are implicated in pathogenesis of the disease.
Development of gastric dysfunction in dermatitis herpetiformis
Authors: Stockbrügger R , Kastrup W , Lundqvist G , Mobacken H
Published: July 2023

In order to study the development of atrophic gastritis, gastric secretory function was examined by a standard pentagastrin test 24 to 78 months after a previous examination (Ex I). The study included 12 patients with dermatitis herpetiformis (DH), 6 patients with functional signs of atrophic gastritis previously, and 8 healthy controls. The surrent examination (Ex II) also included microbiological culture of gastric juice and estimation of gastrin(s), parietal cell and thyroidal antibodies. Most of the controls had increased their maximum acidity and maximum acid output (MAO) between the examinations. This may indicate an altered potency of pentagastrin in recent years. Conversely, 5 of the 6 patients with atrophic gastritis showed a further reduction of maximum acidity and MAO, indicating progressive parietal cell atrophy. In the DH-group, two tendencies were observed: 6/12 patients had an increased MAO at Ex II. They had had lower mean age and higher mean MAO at Ex I, as compared with the remaining 6 patients who had a decreased MAO at Ex II. The latter group more often had parietal cell antibodies.
Rapid diagnostic tests for cutaneous eruptions of herpes simplex
Authors: Veien NK , Vestergaard BF
Published: July 2023

Comparison was made of the results of virus isolation, indirect immunofluorescent staining (IF-test) and Tzanck smears from 32 patients with cutaneous eruptions clinically diagnosed as herpes simplex. Herpesvirus hominis was isolated from 21 patients; IF-test was positive in 22 patients; Tzanch smears were positive in 20 patients. 23 to 25 of the 25 patients in whom one of the diagnostic tests was positive could be identified by a combination of any two of the diagnostic methods employed. No false-positive reactions were observed for IF-test or Tzanck smear.
Treatment of scabies with disulfiram and benzyl benzoate emulsion: a controlled study
Authors: Landegren J , Borglund E , Storgårds K.
Published: July 2023

In a double-blind study, 38 adults with scabies were treated with the scabicide Tenutex (a proprietary aqueous emulsion containing 0.5% DDT, 2% disulfiram and 22.5% benzyl benzoate) and 42 patients were treated with a similar emulsion lacking DDT. The treatment consisted of a single whole-body (except for the head) application which was washed off after 24 hours. When examined 3 weeks later, both groups were completely cured. Thereafter, a further 35 patients took part in an open trial with the DDT-free Tenutex emulsion and all patients were cured, irrespective of whether the treatments were administered by skilled personnel or by themselves at home. It is concluded that for the treatment of scabies in Sweden, the most commonly used preparation, Tenutex, can be replaced, without risk of loss of efficacy, by an emulsion containing 2% disulfiram and 22.5% benzyl benzoate, i.e. Tenutex without DDT.
Excretion of 5-s-cysteinyldopa in humans with genetically dark skin
Authors: Agrup G , Hansson C , Juldorf F , Rorsman H , Rosengren AM , Rosengren E.
Published: July 2023

Urinary excretion of 5-S-cysteinyldopa was investigated in 12 genetically dark-skinned men living in Sweden. Ten subjects showed excretion values in the same range as persons of Swedish origin, whereas the excretion was higher in 2 subjects.
The microstructure of the root of Euryale ferox Salisb. (Nymphaeaceae) from the Russian Far East
Authors: Цыренова Д.Ю.
Published: July 2023

В статье представлены результаты анатомиче- ского исследования корней редкого в Дальневосточном реги- оне России представителя водной флоры Euryale ferox Salisb. из семейства Nymphaeaceae. Корни исследуемого вида ха- рактеризуются первичной структурой с типичными пропорци- ями гистолого-топографических зон. Отмечается общая аэ- ренхиматизация тканей в связи с адаптацией к водной среде обитания. Органоспецифические признаки – полиархная сте- ла, эндодерма с поясками Каспари, нередуцированные трахе- альные элементы ксилемы. Выявленная первичная структура корня E. ferox свидетельствует о его родстве с однодольными.
Assessment of soil changes causing contamination with crude oil and mineralized liquids in the Middle Ob region (Western Siberia)
Authors: Носова М.В. , Середина В.П. , Стовбуник С.А.
Published: July 2023

Рассмотрено влияние высокоминерализованных вод и сырой нефти на свойства подзолистых и аллювиальных почв Западной Сибири. Специфическая особенность почв, загрязненных при добыче нефти минерализованными вода- ми – накопление легкорастворимых солей, сопровождающее- ся высоким содержанием токсичных солей. Формирование со- левых аккумуляций и химизма засоления почв на территориях нефтедобычи зависит как от вида загрязнения (сырая нефть, минерализованные жидкости), так и от почвенно-экологиче- ских условий (положения в ландшафте, гидрологического ре- жима, типа почв, их сорбционных свойств, режима поступле- ния солей). Сброс минерализованных вод в ходе аварийных разливов минерализованных жидкостей в условиях переув- лажненных таежных ландшафтов Западной Сибири приводит к образованию техногенно засоленных почв на территориях, где естественное развитие этого процесса невозможно. За- соление почв в условиях гумидного климата можно считать наложенным почвообразовательным процессом, формирую- щим дополнительный риск развития в почвах техногенного со- лончакования. Обнаруженные изменения позволяют оценить экологическое состояние почв (химизм, степень засоления, запас токсичных солей) и разработать предложения по ре- культивации почв нефтесолевого загрязнения.

The influence of highly mineralized waters and crude oil on the properties of podzolic and alluvial soils in Western Siberia is analyzed. Soils contaminated with mineralized waters during oil production accumulate easily soluble salts, as shown by the amount of dense residue within the contamination halo (0.30–1.68%), including high content of toxic salts (toxic chloridesulfate and sulfate anions and toxic cation sodium), which create an unfavorable environment for the growth and development of higher plants. Salt accumulation and the chemistry of soil salinization in oil production areas depends both on the type of pollution (crude oil, mineralized waters) and on soil-ecological conditions (landscape position, hydrological regime, genetic type of soils and their sorption properties, regime of salt supply). The discharge of mineralized waters during spillages in waterlogged taiga landscapes of Western Siberia leads to technogenic halogenesis (salinization) in areas where this process could never have occurred naturally. Soil salinization, which occurs in a humid climate, can be considered a superimposed soil-forming process, which forms an additional risk of the development of an accompanying solonchak process in soils. The changes revealed allow the ecological state of soils to be assessed. Proposals for the reclamation of oil-salt contaminated soils can be put forward, based on basic parameters of technogenically saline soils (chemistry, degree of salinization, and stock of toxic salts).
Å danne politiske borgere – Ole Gabriel Uelands innsats for forbedret politisk opplysning
Authors: Roos Merethe
Published: July 2023

This chapter will shed light upon Ole Gabriel Ueland’s proposal to establish a stortingstidende in 1836, a regular paper aiming to mediate the discussions at the Storting to a broader audience. Ueland, who was one of Hans Nielsen Hauge’s followers, was one of the leading politicians in the Norwegian peasant opposition from the 1830’s, and he is known as a driving force behind the Presidency Act in 1836. This act secured that Norway gained a higher degree of local self-government. I will argue that Ueland’s proposal can be seen in a time-typical tension between agitation and enlightenment, and that the proposal must be understood against his background in the Hauge movement. While most Norwegians at that time only had basic skills in reading and writing, Hauge’s followers possessed a higher level of competence and would be able to read and understand the content of a stortingstidende.
Ideologiske skillelinjer og politiske konfliktarenaer mellom haugianere, liberale bønder og bønder flest i tiårene etter 1814
Authors: Nymark Kristian H.
Published: July 2023

In the Norwegian constitution of 1814, farmers, both land-owning and tenants who paid taxes, were granted the right to vote and to represent their constituency in Parliament. During the first turbulent years of the independent Norwegian state, the farmers were largely quiet. But nearing the end of the 1820’s, the farmers became more vocal, and political campaigns to encourage farmers to vote for each other were set in motion. This mobilisation effort manifested itself in the Norwegian parliaments of 1833 and 1836/1837, where the majority of the representatives belonged to the extended oppositional grouping, often labelled “the farmer’s opposition.” However, this group of oppositional farmers was not homogenous. A significant part of the group were not, in fact, farmers at all. They were rather civil servants or members of the bourgeoise with a liberal political outlook, finding common ground with the oppositional farmers. In addition, the farmers themselves differed in their political goals and ambitions. This article highlights the divisions and tensions between two factions within. On the one hand, there were farmers who wanted a far-reaching liberal platform combined with a program of political enlightenment of the peasantry. They wanted to educate the farmer class, transform them into conscious citizens, thus empowering them and making them ready to take charge of the state. One the other side of the oppositional spectrum, there were the members of the Haugean movement, together with the great majority of the farmers, who were almost exclusively engaged in policies that directly affected their own estate and stayed out of discussions regarding other matters of state. The tensions between these two factions contributed to the lack of a united leftist movement in Norway until the 1860’s.