bluuebunny/crossref_metadata_2025 huggingface dataset:
Peningkatan pengetahuan petugas ahli teknologi laboratorium medis (atlm) terkait manajemen pengelolaan spesimen urine melalui webinar
Authors: Parwati Putu Ayu , Saraswati Ni Luh Gede Intan , Sari Niken Ayu Merna Eka , Laksmi I Gusti Ayu Putu Satya , Resiyanthi Ni Komang Ayu
Published: January 2023

Pengelolaan specimen urine merupakan salah satu hal yang harus dilakukan di laboratorium klinik. Tahap pengelolaan specimen urine dilakukan dari tahap pra analitik, analitik dan pasca analitik. Untuk mencapai mutu hasil laboratorium yang memiliki ketepatan dan ketelitian tinggi maka seluruh metode dan prosedur operasional laboratorium harus terpadu. Akan tetapi, masih sering dijumpai ketidaksesuaian antara hasil pemeriksaan laboratorium dengan keadaan klinis pasien. Hal ini dapat diakibatkan pemeriksaan laboratorium yang dilakukan tidak sesuai prosedur. Kesalahan tahap pra-analitik memberikan kontribusi paling besar pada kesalahan laboratorium. Salah satu kesalahan pada tahap pra-analitik yang sering terjadi adalah penundaan pemeriksaan sampel yang dapat menyebabkan kualitas sampel atau bahan pemeriksaan berubah. Tujuan kegiatan ini adalah meningkatkan pengetahuan dengan memberikan informasi kepada petugas ATLM terkait manajemen pengelolaan spesimen urine. Metode yang digunakan dalam pengabdian masyarakat ini adalah metode ceramah dan diskusi online melalui zoom meeting serta pengumpulan data pengetahuan dilakukan menggunakan google form. Sasaran kegiatan yaitu petugas ATLM sebanyak 100 orang. Uji analisis menunjukkan hasil p-value sebesar 0.000 yang berarti terdapat perbedaan hasil pre-test dan post-test petugas ATLM yang menandakan terdapat peningkatan pengetahuan peserta terkait manajemen pengelolaan specimen urine setelah mengikuti webinar. Melalui kegiatan ini diharapkan peserta mampu mengaplikasikan manajemen pengelolaan spesimen urine  dalam proses pelayanan di laboratorium klinik.
DO NOT JUDGE THESE POTATOES BY IT PEEL:
Authors: Afrianto Whisnu Febry , Budiyoko Budiyoko
Published: January 2023

Even though these products have the same nutritional content, imperfect vegetable and fruit products are often ignored and discarded by consumers. This condition has resulted in an increasing problem of food loss and food waste, from the producer to the consumer level. This paper aimed to investigate consumer perceptions of imperfect vegetable products. The research design used two approaches, such as (1) hedonic test experiments and (2) group discussion forums (FGD). The participants were urban people who were living in Jakarta. Participants assessed the level of preference (hedonic) on color, aroma, texture, and taste. Potatoes used in this study were (Sample 1) potatoes grade A and (Sample 2) potatoes grade B. Potatoes sample 1 has a good shape, size, and only a minor blemish level. In contrast, potatoes sample 2 has a smaller size, not good condition, and blemish level. Investigation through the Mann-Whitney test showed that all parameters were not significantly different (p<0.05) for all variables. This indicated that consumers could accept imperfect produce. However, in terms of consumer behavior, cosmetics and appearance products are considered in choosing potatoes.
COMMUNITY-BASED ACTIVITY OF NURSERY RAISING FOR IMPROVING THE LIVELIHOOD OF SMALL SCALE’ FARMER in District Kurram
Authors: Ahmad Farhan , Khan Iftikhar , Nasib Muhammad , Sher Ali
Published: January 2023

Income generation through community-based Nursery raising technique, Nursery raising, and maintenance in the area is a new Intervention being carried out in the villages of Kurram. In selected villages, poor and deserving farmers were selected to execute the activity to improve the livelihoods of the deserving and needy beneficiaries selected in the Broad-Based Community Meeting (BBCM) for Nursery Raising activity. A total of 124 beneficiaries in Kirman Mamuzai, Kirman Mata, Shakh, and Shaikh Dawlat Khel villages were identified for 24 different nurseries as simple randomized sampling. The data were analyzed descriptively in a one-sample t-test in different training sessions to manage the nurseries accordingly. The result showed that nurseries activity could be sustained for developing entrepreneurship. There has been an increasing demand for fruit plants plantation more. Nursery product is no longer restricted to large parks and gardens. It has entered into a high rise. Walnut, Pomegranate, Peach and Apricot plantation, etcetera. Heavy demand is observed during the assessment phase of the project. Whether local or introduced species, Nursery Seedlings have better survival than seeds sown directly in the Kurram district. So, nursery seedling becomes the planting material for plantations is a high source of Income.
START-UP DAN MOTIVASI BERWIRAUSAHA OWNER COFEE SHOP DI KAWASAN HERITAGE PUPUTAN BADUNG
Authors: Dewi Anak Agung Istri Agung Peradnya , Arisena Gede Mekse Korri , Ustriyana I Nyoman Gede
Published: January 2023

ABSTRAK
Dengan meningkatnya mobilitas dan gaya hidup masyarakat yang dipengaruhi oleh budaya luar, khususnya di Kota Denpasar pada kawasan Heritage Puputan Badung ini menyebabkan marak berkembangnya bisnis yaitu bisnis start-up coffee shop. Dibalik maraknya hal tersebut tentunya bukan tanpa sebab melainkan terdapat kiat-kiat yang dilakukan oleh pemilik saat mendirikan bisnis start-up coffee shop di kawasan Heritage Puputan Badung, oleh karena itu penelitian ini bertujuan : 1) menganalisis karakteristik owner, 2) menganalisis bisnis start-up coffee shop, 3) menganalisis dan mengetahui motivasi berwirausaha dari para bisnis start-up coffee shop di kawasan Heritage Puputan Badung. Penelitian ini menggunakan analisis deskriptif kualitatif dengan tabulasi data sederhana. Informan ditentukan dengan metode sensus, data penelitian diperoleh melalui wawancara mendalam dan terstruktur, observasi, serta dokumentasi. Hasil penelitian menunjukkan bahwa: 1) Owner coffee shop di kawasan Heritage Puputan Badung sebagian besar merupakan golongan generasi Y (25-39 tahun) berjenis kelamin laki-laki bekerja sebagai wirausaha dengan modal bisnis dari puluhan juta rupiah hingga milyaran rupiah dan rata-rata pernah memiliki pengalaman berbisnis sebelumnya 2) Bisnis start-up coffee shop di kawasan Heritage Puputan Badung sudah tergolong rintisan yang berdiri selama 1-4 tahun dengan 2 hal utama memutuskan untuk mendirikan di kawasan heritage beserta 3 tahap pengembangannya diikuti dengan 5 tahapan start-up di dalamnya dan 9 proses utama dalam mendirikan sebuah bisnis start-up .[i] 3) Ke 22 Owner bisnis start-up coffee shop memiliki 3 kebutuhan yang digunakan sebagai motivasi berwirausahanya pada kawasan Heritage Puputan Badung yaitu kebutuhan akan prestasi, afiliasi, dan kekuasaan.
Preocupações pedagógicas de estudantes em formação inicial e sua relação com os estágios curriculares supervisionados: uma revisão sistemática
Authors: Belem Isabella Caroline , Both Jorge
Published: January 2023

OBJETIVO: O objetivo desta investigação foi realizar uma revisão sistemática sobre os estudos que analisaram as preocupações pedagógicas de estudantes estagiários do curso de Educação Física.MÉTODOS: As buscas e a seleção dos artigos foram realizadas pela pesquisadora responsável, entre os meses de fevereiro e julho de 2022 nas bases de dados: Ebsco, Scopus, Web of Science, Scielo e Lilacs. Foram analisadas publicações do ano de 1985 a julho de 2022. Encontrou-se 1.482 artigos, dos quais 14 artigos atendiam aos critérios de inclusão. RESULTADOS: Os estudos analisados apontaram que as preocupações docentes estão relacionadas a relacionadas a prática docente, fatores sociodemográficos e aspectos psicológicos como ansiedade, esperança, medo. As maiores preocupações dos estudantes foram quanto a sua sobrevivência o campo de trabalho, ou seja, consigo. E ainda quanto ao impacto da tarefa, o que está relacionado aos problemas vivenciados durante a docência, sobretudo com os aspectos sociais, cognitivos e emocionais dos alunos.CONCLUSÃO: Conclui-se o início na docência é permeado de preocupações, e que no caso de estudantes em situação de estágio estas podem ocorrer em dois extremos de acordo com a Teoria proposta por Fuller e Bown (1975), sendo estas consigo e com o impacto da tarefa.
منهج القرآن الكريم في صياغة التراكيب الدالة على الحكم الشرعي وأثرها على التفسير
Authors: عسيري دلال علي جابر , بوزيان مريم عطية
Published: January 2023

هذا البحث المعنون بمنهج القرآن الكريم في صياغة التراكيب الدالة على الحكم الشرعي وأثره على التفسير، هو جزءٌ من رسالة نوقشت للحصول على دجة الماجستير بعنوان: منهج القرآن الكريم في صياغة الحكم الشرعي  وأثره على التفسير. تناولت فيه منهج القرآن في استخدام التراكيب الدالة على الحكم الشرعي وأثرها على المنهج التفسيري. وقد تطّرقت فيه للقرائن الداخلية المؤثرة في صياغة نص الحكم الشرعي والمتمثلة في قرائن النص القريب، والقرائن الداخلية للنص البعيد ، كما تناولت  القرائن الخارجية في صياغة نص الحكم والمتمثلة في قرينة أسباب النزول وقرينة الخطاب وقرينة البيان بالسنة وقرينة النّسخ مع بيان أثر ذلك في التفسير.
Tebet Eco Park’s potential as a new green open space in South Jakarta, Indonesia: an analysis
Authors: Suryantari Yulita , Ngarbingan Hubertina Karolina , Akbara Anisa Zahwa
Published: January 2023

Tebet Eco Park is a new green open space in South Jakarta. The aims of this study is to analyze the condition of the facilities, potential visits, and provide suggestions for better Tebet Eco Park. The type of this study is descriptive qualitative research. The methods for collecting the data are observation, interviews, and documentation. The Miles Huberman methodology, which consists of data reduction, data display, and data verification, is used to analyze research data. Tebet Eco Park contains eight different zones, and the facilities are in good and clean condition. In this research, eco park has good pull factors such as easy access, free prices, good facilities, and good staff service but does not guarantee that the revisit intention of visitors will always be positive. It is hoped that on weekends and holidays, eco park limit the number of visitors to enjoy the environment for a longer period of time. Visitors also want to come back if the place is not too crowded, and want to recommend Tebet Eco Park to their relatives. The first suggestion for organizers is to lower the visiting cap on weekends, and holidays. The second is to create an online visitor survey. The third is to construct a lactation area. The fourth is to create an activity calendar for the Eco Park.
Kepariwisataan di masa krisis: kunjungan wisata pada masa pandemi covid-19 di pantai Pangandaran, Indonesia
Authors: Hulu Meitolo , Ariyanti Lidia
Published: January 2023

This study uses a qualitative approach by conducting interviews and observations of tourism business actors and visitors in Pangandaran beach tourism area. The focus of the study is on the difficulties faced by tourism business actors and explore the experience of visitors on Pangandaran beach during the Covid-19 pandemic. This research was conducted with a descriptive qualitative approach with primary and secondary data collection. Primary data collection was carried out through interviews and observations by adhering to strict health protocols. While secondary data is done through the collection of documents related to research studies online and offline. The results of this study indicate that the difficulties faced by tourism business actors in the Pangandaran coastal area during the Covid-19 pandemic are experiencing an economic decline and information uncertainty regarding the closure of tourism destinations. Meanwhile, visitors have difficulty accessing tourist destinations due to mobility restrictions in some areas. The policy of restricting access in several regions in Indonesia has a broad impact on other tourism destinations, and one of them is Pangandaran beach tourism area. It takes commitment from tourism businesses and awareness from visitors is the main key in implementing health protocols.
Manajemen daya tarik wisata religi studi kasus makam Habib Ahmad Bin Ali Bafaqih, Yogyakarta
Authors: Panghastuti Tuti , Shalawati Aisyah
Published: January 2023

This study aims to find out how the management of religious tourism attractions in the Tomb of Habib Ahmad bin Ali Bafaqih and find out what are the supporting and inhibiting factors for the management of religious tourism attractions. The type of this research is descriptive qualitative research with data collection methods used are interviews, observation and documentation. The results showed that the management of religious tourism at the tomb of Habib Ahmad Bafaqih was managed directly by the heirs by implementing management functions, namely by planning, organizing, mobilizing and supervising the program of religious activities in the tomb.
Tratamiento quirúrgico de incisivo central superior incluido, dilacerado horizontal
Authors: Miranda Espinoza Jorge Israel
Published: January 2023

Introducción: La exodoncia de un diente incluido, se decide cuando su recolocación es imposible o el factor económico impide al paciente realizar un tratamiento ortodóntico, para una mejor respuesta posoperatoria se emplean los concentrados plaquetarios. El plasma rico en plaqueta, es un concentrado sanguíneo de uso odontológico en regeneración de tejidos, el presente trabajo describe el tratamiento quirúrgico de un incisivo central superior retenido, dilacerado, horizontal. Caso clínico: Paciente adulto femenino acude a consulta, sin ningún tipo de sintomatología, a la exploración intraoral se denota la ausencia de una pieza dental. La radiografía panorámica y tomografía confirma la inclusión y localización en sector anterior del maxilar, se hizo el centrifugado de la sangre y se procedió con la cirugía respetando el protocolo establecido y los tiempos operatorios, una vez extraída, se insertó el plasma rico en plaquetas y se hizo la sutura. Se dieron las recomendaciones posoperatorias, se programaron los controles, se observó que existe un mejor resultado posoperatorio en tejido óseo y gingival. Discusión: Los factores causales son: posición irregular o presión adyacente, presencia de quistes o supernumerarios, densidad del hueso o fibromucosa gruesa, extracción prematura, falta de espacio en la arcada dentaria, anomalías de tamaño y forma. Los efectos obtenidos son similares a los indicados por varios estudios donde mencionan: encía delgada, sin inflamación, de color rosado y sin sangramiento, aceleración del proceso de reparación ósea.
IN VIVO ACTIVATION OF P2Y4 PURINERGIC RECEPTORS USING ATP IN RAT EPIDERMAL TISSUE
Authors: Dosh Rasha Hatem , Khalfa Hydar Muhsin , Al-Rehemi Siham Mahmood , Almsaid Hayder Lateef , Hadi Najah
Published: January 2023

The aim: This study was carried out to examine the presence of P2Y4 receptors in rat epidermal tissue and how their in vivo activation leads to histological and genetic changes.
Materials and methods: Thirty-six Wistar rats were separated into six groups each of six rats, the control group and five injected groups with increasing concentrations of ATP intradermally (0.1, 5.0, 10.0, 50.0, 100.0 μg/ml). The histological and genetic examination was performed from excised tissues.
Results: Noticeable histological thickening of the epidermal layer in rats injected with high concentrations of ATP. No apparent histological damage was seen in all injected groups. The genetic expression seems to also increase following exposure to variable concentrations of ATP.
Conclusions: Purinergic receptors activated by ATP molecules are highly involved in the development of adult tissues. Their precise location within the epidermal layer indicated their importance in cellular proliferation and differentiation of epidermal cells. Excessive exposure to ATP results in their robust genetic ectopic over expression indicative of increased cellular activity.
OPTIMIZING DISTRACTION OSTEOSYNTHESIS IN PATIENT WITH THE TIBIAL SEGMENT TISSUE LOSS AFTER FRACTURES
Authors: Sobolevskiy Yuriy , Rushay Anatoly , Burianov Olexandr , Lisaichuk Yury , Kvasha Volodymyr , Kovalchuk Dmytro , Omelchenko Taras
Published: January 2023

The aim: Improving treatment outcomes in patients with segment tibial bone tissue loss after fractures by improving the ring fixators technology.
Materials and methods: The study includes the data of 77 patients. The patients were distributed between two groups: the main and control one, using random numbers table. The inclusion criteria were: patients’ consent, their age over 18 years, tissue inflammation episodes, fibular defects 4-5cm in size and disseminated scar lesions. RF was applied with the proposed improvements. Finally, a semi-rigid external fusion system Softcast / Scotchcast was used to prevent deformation of the regenerate and create optimal conditions for fusion of fragments.
Results: The following results were obtained for the Modified Functional Evaluation System by Karlstrom-Olerud: positive treatment outcomes in the main group made up 97.1%, and 92.9% in the control one. Though, the specific gravity of good and excellent outcomes in the main group was 82.8%, while in the comparison group – just 45.2%
Conclusions: Along with considerable positive advantages of the “Ilizarov’s” apparatus, some disadvantages have been noted. Elimination of the drawbacks is stipulated for the practical needs, which requires further scientific study.
EVALUATION OF THE EFFECT OF TOPICALLY APPLIED METHYLSULFONYLMETHANE AND THEIR COMBINATION WITH MINOXIDIL SOLUTION FOR IMPROVEMENT OF HAIR GROWTH IN MALE MICE
Authors: Hummadi Ammar A. , Gany Sarmad N. , Hadi Najah R.
Published: January 2023

The aim: The purpose of this research was to find out the effect of Methylsulfonylmethane in minimizing hair loss.
Materials and methods: Twenty adult Wister Albino mice weighing 25-35g and aged 6-7 weeks were employed. Male mice’s coat hairs on the dorsal skin were carefully clipped and then colored. Mice were randomly assigned into four groups, each with five animals: (1) Control group: Treated with D.W. (2), Minoxidil (5%) treated group (3), Methylsulfonylmethane (10%) treated group (4), Methylsulfonylmethane plus Minoxidil treated group.
Results: We found that the tissue level of 8-isoprastanein the groups receiving medication are considerably lower than in the control (D.W.). We also discovered that the serum tissue vascular endothelial growth factor levels in the groups receiving medication are considerably greater than those in the control (D.W.) groups. On the other hand, we discovered that hair growth, hair follicle expansion and hair follicle number are much higher in the groups receiving medication than in the control groups.
Conclusions: We concluded that MSM, through its antioxidant and anti-inflammatory properties, dramatically reduces hair loss in male mice.
THE MAIN ASPECTS OF COUNTERING PANDEMIC INFECTIOUS DISEASES THROUGH VACCINATION IN THE CONTEXT OF PROTECTING HEALTH AND OVERCOMING PSYCHOLOGICAL BARRIERS
Authors: Bilyk Valentyna , Dimitrova Alla , Havrychenko Dmytro , Stelmakhivska Valentyna , Vorontsova Tetyana
Published: January 2023

The aim: Study of opinions and attitudes of citizens towards vaccination, identification of the reasons for the refusal of vaccination, the main psychological barriers.
Materials and methods: As a result of the analysis the main reasons for the refusal of vaccination were systematized into 5 groups. For practical clarification of the main reasons for the refusal of vaccination, we conducted a survey of citizens of the family medicine outpatient clinic in one of the Ukrainian cities. A total of 30 respondents took part in the survey.
Results: The results of the survey were systematized, according to which it was found that today there is still a negative attitude towards vaccination, although some of the respondents who have a positive attitude towards vaccination are much larger in the context of today’s pandemic realities. The main reason for not vaccinating is a lack of trust and confidence in vaccine safety.
Conclusions: To date, vaccination, including against COVID-19, is the only method of combating the pandemic. The identified reasons for the refusal of vaccination, according to the authors, are due to the lack of proper informatization of the population and the low level of trust in global and national medical institutions.
SYSTEM OF PROFESSIONAL COMMUNICATIVE LITERACY FORMATION FOR FUTURE MEDICAL WORKERS THROUGH THE PRISM OF LANGUAGE TRAINING
Authors: Fedchyshyn Nadiya O. , Chornobryva Nataliia V. , Fedchyshyn Olena I. , Tsaryk Olga M. , Pantiuk Mykola P. , Fedoniuk Larysa Ya. , Nakhaieva Yaryna M.
Published: January 2023

The aim of the study is to analyze the formation of professional communicative literacy of future medical workers, which includes a personal development component provided by independent language preparation for the use of medical terminology.
Materials and methods: The diagnostic stage, which was conducted in 2019-2020, included 400 students from four higher educational institutions: I. Horbachevsky Ternopil National Medical University, Danylo Halytsky Lviv National Medical University, Ivano-Frankivsk National University, Uzhhorod National University. These are students who completed the study of such disciplines as “Latin language and basics of medical terminology”, “Human anatomy”, “Histology”, “Pharmacology” in the 1st year of studying.
Results: The comparative analysis shows that this determined the level of formation of the students’ motivational sphere in the direction of speech preparation for the use of medical terminology in Latin language classes, and the following results were obtained. With regard to the main motivating points for Latin classes, it was established that 115 (28.75%) young people study it with great interest, strive to improve their knowledge of medical terminology further, as they are sure that they will definitely need it in their future professional activities.
Conclusions: Research and experimental verification of the effectiveness of pedagogical conditions and the structural-functional model of professional language training of future doctors for the use of medical terminology took place during the training of first-year-students at the higher educational establishment. Innovative methods of developing critical thinking, information and interactive technologies were used.Positive changes in the results of professional and language training of CG students (increase in average figure from 3.51 to 3.69 points) are caused by the natural influence of the traditional educational process, and changes in average figures in EG (from 3.51 to 3.92 points) show the effectiveness of implementation of defined pedagogical conditions.
THE RELEVANCE OF RS6777038 AND RS6444082 OF IGF2BP2 GENE POLYMORPHISM AND TYPE 2 DIABETES MELLITUS: A CASE CONTROL STUDY
Authors: Mohammed Noaman Ibadi , Alzubaidi Zubaida Falih , Khudhair Muneer
Published: January 2023

The aim: We investigate IGF2BP2 gene polymorphisms (rs6777038 and rs6444082) association with T2DM of Iraqi sample.
Materials and methods: The study involves 800 participants that divided to a healthy control group (400) and T2DM patients (400). Fasting blood sugar (FBS), triglycerides (Tgs), high-density lipoprotein cholesterol (HDL-Ch), total cholesterol (T-Ch), low-density lipoprotein cholesterol (LDL-Ch), and fasting insulin measured for both participant groups. IGF2BP2 gene has been genotyped for polymorphisms, rs6777038 and rs6444082 using the PCR-RFLP technique.
Results: Logistic regression analysis testing for rs6777038 revealed that the genotype and allele frequency differ significantly (p=0.009) between T2DM and control group. In codominant model, TT genotype carriers had higher risks for diabetes than control also in the recessive model TT genotype significantly had higher risk for diabetes than control group. The other models of rs6777038 failed to reveal significant differences. The rs6777038 genotypes as codominant model showed significant differences with phenotypic characters of BMI, insulin and HOMA-IR. As well as, this SNP as dominant model showed significant differences with fasting insulin and HOMA-IR. However, rs6444082 genotypes only as dominant model reveal significant variation with HOMA-IR.
Conclusions: This study confirmed the variant rs6777038 of IGF2BP2 possibly associated with T2DM risks and some anthropometric parameters such as lower fasting insulin, HOMA-IR and BMI in Iraqi T2DM participants.
METABOLIC AND HORMONAL FEATURES OF CHRONIC HEART FAILURE IN PERSONS WITH POST-INFARCTION CARDIOSCLEROSIS WITH TYPE 2 DIABETES MELLITUS AND OBESITY
Authors: Bilovol Olexandr M. , Dunaeva Inna P. , Kravchun Pavel P.
Published: January 2023

The aim: To determine the role of lipid metabolism and fractalkin and clusterin in the progression of chronic heart failure in patients with postinfarction cardiosclerosis with concomitant type 2 diabetes and obesity.
Materials and methods: A retrospective analysis of a comprehensive examination of 67 patients with postinfarction cardiosclerosis with concomitant type 2 diabetes and obesity. All patients were divided into 3 groups depending on the functional class (FC) of CHF: 1 group (n = 22) – patients with CHF II FC; Group 2 (n = 23) – patients with CHF III FC; Group 3 (n = 22) – patients with CHF IV FC. All patients were examined clinically, they were instrumental, biochemical and hormonal examination.
Results: With the progression of CHF from FC II to FC III there is a deterioration of lipid metabolism: a significant increase in cholesterol levels by 5.5%, TG – by 15.7%, LDL cholesterol – by 74.4%, VLDL cholesterol – by 15 , 9%, reduction of HDL cholesterol – by 27.6% (p <0,05). An analysis of the fractal equation showing that ailing on CHF is advised by FC; rіven clusterin –decrease.
Conclusions: Classical changes in patients with postinfarction cardiosclerosis with CHF and concomitant type 2 diabetes mellitus and obesity , which are the formation of atherogenic lipid metabolism disorders associated with body weight, as well as changes in the latest indicators such as fractalkin and clusterin , indicating the role of these molecules in the progression of CHF.
VOLUNTEER MOVEMENT OF UKRAINIAN STUDENTS IN THE FIELD OF MEDICAL AID, EDUCATION, HEALTH CARE FOR CHILDREN AND ADULTS (END OF THE XIX – 30S OF THE XX CENTURY)
Authors: Bilavych Halyna V. , Tkachivska Inna M. , Rozman Iryna I. , Didukh Iryna Ja. , Fedchyshyn Nadiya O. , Fedoniuk Larysa Ya. , Savchuk Borys P.
Published: January 2023

The aim is to analyze the leading directions of volunteer activity of Ukrainian students in the field of medical, social assistance, education of children, youth and adults in Galicia (end of the 19th – 30s of the 20th century).
Materials and methods: The study uses a number of scientific methods: chronological, historical, specific search, content analysis – provide selection, analysis of the source base, allow to identify general trends, directions of development, achievements and gaps of the Ukrainian student movement in Galicia in the field of medical, social care, education and enlightenment of children and adults in the late XIX – 30s of the XX century; extrapolation and actualization – focus on creative thinking, adaptation and use of this historical experience under the current conditions.
Conclusions: Voluntary activity of Ukrainian students (end of the 19th – 30s of the 20th century) is an interesting peculiar phenomenon not only in national, but also in European history, which has real achievements and deserves a scientific and theoretical understanding from the standpoint of today. Student volunteer experience in the field of social and medical protection of children and adults, education, cultural development, promotion of a healthy lifestyle, dissemination of sanitary and hygienic knowledge, medical counseling can be useful and instructive now, when Ukraine is fighting against the Russian aggressor. We outline the volunteer activity of students who belonged to the “Medychna hromada” society (1910-1944) as a national phenomenon of the organization of public medical care of the population of Galicia, which has no analogue in the history of Ukrainian medicine. It is primarily about a high degree of civic self-awareness, patriotism, self-sacrifice for the benefit of the Ukrainian people, the provision of medical services to low-income sections of the population, widows, orphans, disabled people, veterans of the Great War, medical care of children and youth, etc. – all this inspires modern doctors who provide assistance to soldiers of the Armed Forces of Ukraine, wounded in hospitals, internally displaced persons, etc.
GENITALS MUTILATING SURGERIES (FEMALE CIRCUMCISION): LEGAL MEASURES OF COUNTERACTION
Authors: Lohvynenko Borys , Chekalovska Halyna , Mykoliuk Svitlana , Yaroshchuk Marianna , Dolga Tetiana
Published: January 2023

The aim: To highlight legal measures of counteraction to genitals mutilating surgeries (female circumcision) and the perspectives for their possible improvement.
Materials and methods: International regulatory legal acts, acts of “soft” law, statistical data, research results are the materials of the research. Comparative, comparative and legal, system analysis, formal and logical, other methods were applied during the research.
Conclusions: It has been proved that although there are four different types of female circumcision, any such surgery performed without medical grounds is female genitals mutilating surgery. The authors have offered to enshrine a direct ban on performing genitals mutilating surgeries (female circumcision) in the norms of national legislation with appropriate measures of legal liability for those involved.
AGGRESSIVE COURSE OF DIFFERENTIATED THYROID GLAND CANCER IN A PATIENT WITH INSULIN RESISTANCE: CASE ANALYSIS FROM PRACTICE
Authors: Pidchenko Nataliia S. , Astapieva Olha M. , Vasyliev Leonid Ya. , Grushka Ganna V. , Paskevych Olga I. , Pushkar Olena S. , Pidlisnyi Ruslan A. , Fedulenkova Yuliia Ya. , Myroshnychenko Mykhailo S.
Published: January 2023

Differentiated thyroid cancer (DTC) is usually characterized by a harmless clinical behavior but in some cases it can manifest itself as a metastatic damage to the bone system. The authors reported case from their practice of an aggressive DTC course in a patient with insulin resistance, accompanied by the development of metastases in the bone system. The main goals of the patient’s treatment at each stage of radioiodine therapy were to reduce the foci of metastatic bone damage in terms of their number and volume as well as insulin resistance as a risk factor affecting insulin-like growth factors.
A clinical case analysis found that radioiodine therapy might be useful for disease control in cases with potentially aggressive variants of DTC. This category of patients requires careful monitoring of insulin resistance, insulin-like growth factors and appropriate antitumor treatment.
ADEQUACY OF BREAST MILK AND THE DEVELOPMENT OF BABIES AGED 1-6 MONTHS
Authors: Juhrotun Nisa  , Umriaty  , Meyliya Qudriani
Published: January 2023

Background: The age of 0-24 months is a period of rapid growth and development, so it is often termed a golden period as well as a critical period. Breast milk (breast milk) is milk produced by the mother and contains the nutrients needed by the baby for the needs and development of the baby. Purpose: This study was conducted with the aim of knowing the relationship between the adequacy of breastfeeding and the development of infants aged 1-6 months. Methode: This research is an analytic survey with a quantitative approach and cross sectional design. The population in this study were mothers and infants aged 1-6 months and received exclusive breastfeeding. The sampling technique used was accidental sampling. The study was conducted at one of Health Center in June to July 2020. Data collection techniques used questionnaires, and filling out the KPSP. Result: The results showed that 72.7% of infants with sufficient breast milk and 51.5% of infants had appropriate development. 62.5% of infants with sufficient breast milk have appropriate development. There is a relationship between the adequacy of breast milk and the development of infants aged 0-6 months who receive exclusive breastfeeding.
SMART ABDOMEN MODEL AS CLINICAL LEARNING MEDIA IN IMPROVING MIDWIFERY STUDENT COMPETENCE IN POSTPARTUM CARE
Authors: Herlyssa  , Elly Dwi Wahyuni  , Jujun Dwi Astuti  , Sri Rahayu
Published: January 2023

This study aims to determine the effectiveness of the "SMART" abdominal model as a clinical learning media in increasing student competence for assessing uterine fundal height in postpartum mothers. This research is a quasi-experimental research with The Posttest-only Control Group Design. The study was conducted in two groups, namely the treatment group and the control group. The population of this study was all students of the third semester of midwifery D III study program in two health polytechnic in Indonesia. The intervention group consisted of some students who were given assistance in using the "SMART" abdominal model to assess the height of the uterine fundus in postpartum mothers in simulated patients, while the control group consisted of some students without assistance in using the "SMART" abdominal model to assess height uterine fundus in postpartum women on a conventional abdominal model (Zoe's abdominal model). The total sample was 120 people, which were divided into 60 people from one Poltekkes as the control group and 60 people from another Poltekkes as the intervention group. The sampling technique was purposive sampling. Data was collected through questionnaires, and observation. The type of data in this study is primary data. Data analysis uses Kai Square. The SMART abdominal model supports the achievement of learning competencies by 81.4%. There was no significant difference in competence when students used the SMART abdominal model on simulated patients or paired them with Zoe's abdominal model. For this reason, innovation and creativity of lecturers are needed in supporting the achievement of subject learning through the development of learning models and technology. In supporting the wider use of the model as a form of downstreaming research products that are integrated into the dharma of education, it is necessary to socialize and disseminate the SMART abdominal model and promote efforts through collaboration with industry and MSMEs.
SYSTEMATIC REVIEW GAMBARAN PENGETAHUAN IBU TENTANG PEMELIHARAAN KESEHATAN GIGI DAN MULUT TERHADAP KEJADIAN KARIES GIGI PADA ANAK PRASEKOLAH
Authors: Sihombing Kirana Patrolina , Siahaan Ruben Putra Bhakti
Published: January 2023

Mother's knowledge gives a very important and big role in directing, providing understanding, improving and providing facilities to children so that they are able to maintain their dental and oral health properly and correctly which will ultimately determine the incidence of dental caries in children. The purpose of this study was to obtain a description of the mother's knowledge about the maintenance of oral health on the incidence of dental caries in preschool-aged children. This research is a systematic review that examines 10 articles published between 2018-2021, obtained from searching the Google Scholar and Proquest databases using the keywords 'mothers and preschoolers' both in Indonesian and English. Based on the results of a review of 10 articles, it is known that 50% of mothers have a very good level of knowledge, and 60% of children have a high incidence of dental caries. This study concluded that the mother's level of knowledge about dental and oral health maintenance was in the good category (5 articles), the mother's level of knowledge was in the fair category (4 articles), and the status of the incidence of dental caries in preschool age children was in the high category (6 articles).

Keywords: knowledge; dental caries; preschool children
FAKTOR-FAKTOR YANG MEMPENGARUHI KEJADIAN PREMENSTRUAL SYNDROME (PMS)
Authors: Wulandari Hesty Fitria , Jubaedah Entin
Published: January 2023

The percentage of PMS occurrence in Indonesia at the age of 16-45 years is 80-90%. Factors causing PMS occur because of stress levels, diet, and exercise activity experienced by adolescents. Therefore, one of the efforts to prevent the occurrence of PMS symptoms is by changing adolescent lifestyle. This study aims to determine the factors that influence PMS in adolescents.This research uses Cross Sectional. The sample of this study used a total sampling technique with consideration of inclusion and exclusion criteria, total of respondents in this study were 70 College Students Nursing Diploma III Poltekkes Kemenkes Tasikmalaya. Data collection using a questionnaire through Google form which was analyzed by Chi-Square test, Kruskall Wallis, Mann-Whitney.The results showed as many as 55.7% experienced moderate symptoms during PMS, experiencing moderate stress as much as 81.4%, doing enough exercise activity as much as 80%, and doing unhealthy diet as much as 84.3%. Based on the bivariate results the relationship between stress levels with PMS obtained p value 0.102 (p ? 0.05). For the relationship with exercise activity obtained p value 0.900 (p ? 0.05), and for the relationship with diet obtained p value 0.194 (p ? 0.05). So it can be concluded that there is no influence between stress level, exercise activity, and diet with the incidence of PMS in adolescents
HUBUNGAN TINGKAT ANXIETY DENGAN KONTROL ASMA BRONKIAL
Authors: Marlin Sutrisna  , Elsi Rahmadani
Published: January 2023

Bronchial asthma is still a health problem that is included in the top 10 deadly diseases in the world. The purpose of this study was to determine the relationship between Anxiety Levels and Control of Bronchial Asthma. The type of research used is descriptive research with a cross sectional research design. The place of research was carried out at the Sukamerindu Health Center in 2020. The sample in this study was bronchial asthma patients, totaling 30 respondents. Measurement of anxiety level using the HARS scale instrument and measurement of bronchial asthma control using the ACT (Asthma Control Test) instrument. Data were analyzed by chi-square. The results showed that more than some respondents had controlled asthma and more than some respondents did not experience anxiety (normal). The results of the chi-square statistical test showed that there was a relationship between anxiety levels and control of bronchial asthma in the Sukamerindu Pueskesmas Work Area, Bengkulu City. The conclusion in this study is that the level of anxiety can affect the control of bronchial asthma. Researchers suggest that the Sukamerindu Public Health Center can provide education to asthma patients so that they can control their anxiety so that asthma becomes more controlled.
PENGARUH PEMBERIAN TERAPI BEKAM TERHADAP PERUBAHAN TEKANAN DARAH PADA PENDERITA HIPERTENSI DI KLINIK BEKAM SEHAT Dr. ABDURRAHMAN PASAR 1 TANJUNG SARI MEDAN SELAYANG TAHUN 2021
Authors: Tinah Tinah , Cecep Triwibowo  , Harijun
Published: January 2023

Hypertension is one of the most common diseases in Indonesia and is the third leading cause of death for all ages (7.4%). Hypertension is defined as blood pressure that exceeds 140/90 mmHg. Management of hypertension can be done with pharmacological, non-pharmacological, tertiary and complementary approaches. One of the complementary therapies used is cupping. Cupping is a cleansing method by removing blood and wind from the body through the surface of the skin by sucking. This study aims to determine the effect of cupping therapy on reducing blood pressure in patients with hypertension. The design of this study was a clinical trial with a one group pretest-posttest design. The number of samples was 30 respondents according to the inclusion criteria, namely hypertension sufferers by performing 1 intervention before and after cupping therapy. The results of statistical tests found that there was a change in blood pressure, namely a decrease with the difference in the mean values ??of systole (4.851) and diastole (4.427). The statistical test used is the Wilcoxon test on systole and diastole showing a value (p = 0.000) which means p value <0.05 so H1 is accepted which means that there is a significant effect of cupping therapy on reducing blood pressure in hypertensive patients at the Health Cupping Clinic dr. Abdurrahman Medan. The researcher's suggestion for future researchers is to examine the effects of long-term cupping therapy.
ANALISIS STATUS KESEHATAN MENSTRUASI DENGAN TINGKAT KELETIHAN REMAJA DI SALAH SATU WILAYAH DI KABUPATEN BANDUNG TAHUN 2022
Authors: Mulyati Iceu , Sri Lestari  , Meda Yuliani
Published: January 2023

Menstruation is a monthly cycle that occurs in a woman, menstruation in adolescents is the main feature of puberty which indicates that the reproductive system has started to function properly. whether there is a relationship between menstrual health status and the level of fatigue in adolescents. The research method used is quantitative analysis with a cross sectional approach with data collection using questionnaires and direct Hb examination, the results of the study show that anemia and dismenore are the main factors that have a relationship directly with fatigue during menstruation the impact of this fatigue will cause a decrease in the ability of adolescents, especially in the learning process so that learning achievement also decreases, for this reason it is necessary to make efforts to deal with complaints or problems during menstruation. One of the management of anemia in adolescents can be by giving blood-added tablets, while menstrual pain can be managed with complementary methods such as consuming herbal drinks, acupressure or other measures.
Review Artikel : Pengujian Analisis Metode Kualitatif Terhadap Kandungan Bahan Kimia Obat Pada Jamu Tradisional
Authors: Shofia Difa Aulia  , Salma Aziz  , Selviani Eka Suci  , Siti Lulu Lutfiah  , Yuliani Dewi  , Lia Fikayuniar
Published: January 2023

Indonesia is known for its biodiversity of various types, for example, plants, in Indonesia there are around 9000 species of plants that have traditional medicinal properties, 5% as phytopharmaca ingredients, and 1000s of plant species that can be used as herbal medicine. People often manage traditional medicinal herbs with medicinal chemicals so that they are not by the regulations set by the government, this is evidenced by the findings of herbal medicine with medicinal chemicals (BKO).. This review article draws from several national and international research journals released in the period 2012-2022, there are findings of herbal medicine in the Bayuwangi area, Jakarta, Banyumas, Rengel District Market, Pekalongan, Bumiayu, Central Market, Curug District and Probolinggo with herbal findings that have efficacy and chemical content of drugs Glibenclamide (Diabetes Jammu), Sildenafil (Men's Strong Herbal Medicine), Furosemide, Phenolphthalein, Sibutramine (Slimming Herbal Medicine) Dexamethasone, Cyproheftadin (Appetite Enhancement Herb), Theophylline (Shortness of Breathing Herbal Medicine), Paracetamol and Phenylbutason (Jammu) Anti-Pain) was obtained from the Qualitative methods of Thin Layer Chromatography, Spectrophotodesintometry, High Performance Liquid Chromatography, UV-Visible Spectrophotometry, and FTIR
POLA ASUH ORANGTUA DENGAN KEJADIAN STUNTING PADA BALITA DI KELOMPOK BKB HI
Authors: Rambe Kumala Sari
Published: January 2023

Stunting or the condition of growth failure in children due to malnutrition is caused by various aspects, ranging from inadequate maternal knowledge, repeated infections, poor sanitation, limited health services or even a combination of all aspects. Therefore, the identification of the main causes of stunting is very important to facilitate efforts to solve it. The type of research used was observational analytic with a cross sectional design. The population in this study were mothers who had toddlers (1-5 years) as many as 40 mothers. The sample in this study using the Acidental Sampling technique. The results of the bivariate analysis test using a simple Chi-square test showed that there was a significant relationship between eating parenting and the incidence of stunting (p < 0.038). there is a significant relationship between health care patterns and the incidence of stunting (p < 0.027). There is no significant relationship between psychosocial parenting and the incidence of stunting (p < 0.205). Suggestions for parents, especially mothers, are expected to pay more attention to food diversity by increasing daily food variations and providing quality time to support activities and accept child behavior that has not been controlled patiently and without coercion or punishment for children.
Compreendendo as linhas de partes iguais do compasso de proporção (1631) pelo teorema de proporcionalidade
Authors: Masseno Thalya Cristiny de Sousa , Pereira Ana Carolina Costa
Published: January 2023

Muitos alunos da educação básica estudam geometria compreendendo apenas seus conceitos teóricos, sem correlacioná-los com a prática. Estudiosos da educação matemática e da história da matemática já realizam pesquisas que possibilitam a correlação. Dentre elas, este artigo explanará uma atividade advinda do estudo do tratado L’usage du compas de proporção, publicado em 1631 por Didier Henrion, que permitiu a construção de atividades que relaciona o teorema de proporcionalidade, o perpendicularismo e o paralelismo, partindo de reflexões na qual os alunos precisam identificar um perpendicularismo para validar um paralelismo, e assim conseguir utilizar os seus conhecimentos sobre o teorema de proporcionalidade. O objetivo é apresentar as aplicações e discursões sobre os conceitos geométricos advindo de um trecho de L’usage du compas de proporção, sobre a construção das linhas de partes iguais contida no compasso de proporção, aplicado em duas turmas de 2° ano do ensino médio. Baseada numa metodologia de abordagem qualitativa de caráter descritivo, tendo sua aplicação apoiada no trabalho em grupo. Em relação aos resultados, alguns alunos até conheciam conceitos teóricos sobre o teorema das proporcionalidades, paralelismos e perpendicularismos. Entretanto, quando necessitavam relacioná-los na prática, não conseguiam diferenciar um esquadro de noventa grau com outros que não era. Dificultando a compreensão e validação de um paralelismo, e por consequência, não conseguiam utilizar seus conhecimentos sobre o teorema das proporcionalidades. Logo, conclui-se que atividade aplicada com os alunos foi importante para eles conseguirem relacionar conceitos geométricos teóricos (perpendicularismo e paralelismo) com a prática, permitindo a ressignificação e a compreensão destes assuntos.
Microbial Characterization of Azotobacter sp Isolates From West Kalimantan in Nitrogen Fertilizer Efficiency in Maize Plants (Zea mays L.) on Peatlands
Authors: Muhtarom Nizari , Sinambela Marudut
Published: January 2023

This study aims to characterize the microbial species Azotobacter sp from peat soil in West Kalimantan, which can bind N, dissolve nutrients P, K and produce indole compounds. This research was carried out in the plant pest and disease laboratory, agronomy laboratory and greenhouse, Faculty of Agriculture, Tanjungpura University, Pontianak. This study used a non-factorial Randomized Block Design (RBD) with four levels of treatment. Inoculation of Azotobacter sp isolates was without inoculation of Azotobacter sp isolate (a0), inoculation of WH.3.2.d (a1) isolate, inoculation of Azotobacter sp isolate WH.2.4 (a2), inoculation of Azotobacter sp WH.3.1.l (a3). The study was carried out from September to November 2021. The results showed that Azotobacter sp inoculation significantly affected the parameters of vigor index, growth synchronously, primary root length, wet weight of normal sprouts, and plant height in the greenhouse. From the bioassay test results on seeds and growth testing for 15 days in a greenhouse, the two best isolates were obtained, namely WH.2.4 and WH.3.1.l isolates.