bluuebunny/crossref_metadata_2025 huggingface dataset:
Possible Mechanisms of Mercury Toxicity and Cancer Promotion: Involvement of Gap Junction Intercellular Communications and Inflammatory Cytokines
Authors: Zefferino Roberto , Piccoli Claudia , Ricciardi Nunzia , Scrima Rosella , Capitanio Nazzareno
Published: December 2017

A number of observations indicate that heavy metals are able to alter cellular metabolic pathways through induction of a prooxidative state. Nevertheless, the outcome of heavy metal‐mediated effects in the development of human diseases is debated and needs further insights. Cancer is a well‐established DNA mutation‐linked disease; however, epigenetic events are perhaps more important and harmful than genetic alterations. Unfortunately, we do not have reliable screening methods to assess/validate the epigenetic (promoter) effects of a physical or a chemical agent. We propose a mechanism of action whereby mercury acts as a possible promoter carcinogen. In the present contribution, we resume our previous studies on mercury tested at concentrations comparable with its occurrence as environmental pollutant. It is shown that Hg(II) elicits a prooxidative state in keratinocytes linked to inhibition of gap junction‐mediated intercellular communication and proinflammatory cytokine production. These combined effects may on one hand isolate cells from tissue‐specific homeostasis promoting their proliferation and on the other hand tamper the immune system defense/surveillance checkmating the whole organism. Since Hg(II) is not a mutagenic/genotoxic compound directly affecting gene expression, in a broader sense, mercury might be an example of an epigenetic tumor promoter or, further expanding this concept, a “metagenetic” effector.
Prostatic Utricle Cyst as the Most Likely Cause in a Case of Recurrent Episodes of Hematospermia
Authors: Feutry Grégoire , De Perrot Thomas , Wirth Gregory J. , Montet Xavier , Martin Steve P.
Published: December 2017

Hematospermia is a clinical symptom that raises anxiety in patients and has various causes, benign and malignant. We report a case of hematospermia for which appropriate multidisciplinary expertise favored a conservative management of a benign prostatic cyst, namely, a prostatic utricle cyst. A cystic lesion found by transrectal ultrasound in the context of hematospermia related to masturbation in a young virgin male patient was investigated with a high-field magnetic resonance imaging (MRI) and an endorectal coil. The association of high-field MRI and endorectal coil leads to high quality images.
Atypical Amniotic Fluid Embolism Managed with a Novel Therapeutic Regimen
Authors: Rezai Shadi , Hughes Alexander C. , Larsen Tracy B. , Fuller Paul N. , Henderson Cassandra E.
Published: December 2017

Amniotic fluid embolism (AFE) is the second leading cause of maternal mortality in the USA with an incidence of 1 : 15,200 births. The case fatality rate and perinatal mortality associated with AFE are 13–30% and 9–44%, respectively. This rare but devastating complication can be difficult to diagnose as many of the early signs and symptoms are nonspecific. Compounding this diagnostic challenge is a lack of effective treatment regimens which to date are mostly supportive. We present the case of a 26-year-old woman who suffered from suspected AFE and was successfully treated with the novel regimen of Atropine, Ondansetron, and Ketorolac (A-OK). The authors acknowledge that this case does not meet the new criteria proposed, by Clark in 2016, but feel that it is important to share this case report, due to dramatic patient response to the provided supportive therapy presented in this case report. We hope this case report will prompt further research into this novel approach to treating AFE with Atropine, Ondansetron, and Ketorolac.
ImmunoMap: A Bioinformatics Tool for T-cell Repertoire Analysis
Authors: Sidhom John-William , Bessell Catherine A. , Havel Jonathan J. , Kosmides Alyssa , Chan Timothy A. , Schneck Jonathan P.
Published: December 2017

Despite a dramatic increase in T-cell receptor (TCR) sequencing, few approaches biologically parse the data in a fashion that both helps yield new information about immune responses and may guide immunotherapeutic interventions. To address this issue, we developed a method, ImmunoMap, that utilizes a sequence analysis approach inspired by phylogenetics to examine TCR repertoire relatedness. ImmunoMap analysis of the CD8 T-cell response to self-antigen (Kb-TRP2) or to a model foreign antigen (Kb-SIY) in naïve and tumor-bearing B6 mice showed differences in the T-cell repertoire of self- versus foreign antigen-specific responses, potentially reflecting immune pressure by the tumor, and also detected lymphoid organ–specific differences in TCR repertoires. When ImmunoMap was used to analyze clinical trial data of tumor-infiltrating lymphocytes from patients being treated with anti–PD-1, ImmunoMap, but not standard TCR sequence analyses, revealed a clinically predicative signature in pre- and posttherapy samples. Cancer Immunol Res; 6(2); 151–62. ©2017 AACR.
Chronic Orbital Inflammation Associated to Hydroxyapatite Implants in Anophthalmic Sockets
Authors: Galindo-Ferreiro Alicia , Elkhamary Sahar M. , Maktabi Azza , Galvez-Ruiz Alberto , Schellini Silvana Artioli
Published: December 2017

Purpose: We report 6 patients who received a hydroxyapatite (HA) orbital implant in the socket and developed chronic orbital inflammation unresponsive to conventional medical therapy. Case Reports: We assisted 6 cases (4 males, 2 females) who received an HA orbital implant in the socket between 2015 and 2016 at King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia, and developed chronic orbital inflammation with chronic discharge, redness, and pain (onset from weeks to over 2 decades after surgery). Computed tomography evaluation indicated inflammation in the orbital tissues, and histological examination showed a foreign body granulomatous reaction mainly localized around and blanching the HA implant. The condition was unresponsive to usual medical treatment and was resolved immediately after implant removal. Conclusions: Chronic inflammation can occur decades after placement of an HA implant in the orbit and can be successfully treated with implant removal.
LITERATURA, MEMÓRIA E NARRATIVA HISTÓRICA EM MOÇAMBIQUE
Authors: Gallo Fernanda Bianca Gonçalves
Published: December 2017

Através do debate em torno do poder pós-colonial nas antigas colônias portuguesas, o presente texto situa os mecanismos de produção de uma história oficial focada na luta de libertação e o modo pelo qual parte da literatura produzida em Moçambique vem oferecendo outras possibilidades de narrativas históricas por meio de temas como, por exemplo, o deslocamento populacional.
DOS (IR)RECONCILIÁVEIS EM RIO DAS FLORES, DE SOUSA TAVARES
Authors: Coelho Lilian Reichert
Published: December 2017

Apresenta uma leitura do romance contemporâneo Rio das Flores (2008), do escritor português Miguel Sousa Tavares, na perspectiva da relação entre literatura, história e política por meio de autores como Marinho, Perrone-Moisés e Dosse. O objetivo foi observar de que modos o romance lida com o acontecimento histórico e seus vestígios. A leitura, conduzida metodologicamente pela indução, orientou-se pela reflexão sobre os posicionamentos políticos da posição dos personagens. Como conclusão, notam-se ambiguidades tanto em relação ao romance histórico quanto no que diz respeito às relações entre Literatura e História nos sentidos políticos atribuídos às ações e sanções dos personagens.
A EPOPEIA INDIANA N’O REI DE BENARES DE FERNANDO LEAL (1846-1910)
Authors: Silva Regina Célia Pereira da
Published: December 2017

Mais conhecido pelas suas traduções feitas do francês do que pelas suas obras literárias, Fernando Leal é um escritor que vale a pena estudar e desvendar não só pelo seu estilo linguístico peculiar mas também pela constante relação dialógica existente entre duas culturas no íntimo do eu-literário. Este estudo focaliza-se, de modo especial, na análise do poema O Rei de Benares, escrito na cidade de Lisboa e destinado a um público formado por crianças. Influenciado pela antiga epopeia indiana, o poema apresenta novos elementos constituitivos da lírica e da poética  provenientes de uma convivência constante de duas culturas diferentes, a portuguesa e a indiana, num mesmo indivíduo. Através da análise e comparação profunda dos textos poéticos quer-se penetrar no sentido último do poema e contribuir para uma nova compreensão sócio-cultural do homem, não só como membro de uma comunidade multicultural mas também como ser dialógico.
GEORGES BATAILLE: TOQUES NA EXPERIÊNCIA, UM CARRO E NOSSA DESESPERAÇÃO
Authors: Lazzareti Angelene , Spritzer Mirna
Published: December 2017

O presente ensaio foi escrito a partir de inspirações provenientes de leituras sobre Georges Bataille, sobretudo as que dizem respeito ao tema da experiência poética. A reflexão conta com os aportes de Jean-Luc Nancy, estudioso de Bataille e pensador da filosofia contemporânea. A experiência poética do limite que transita entre a presença e a ausência pretende, a partir dessa reflexão, desenhar um corpo de pensamento que se desconhece na escuridão que deseja e sobre a qual não possui outra possibilidade a não ser lançar-se.
O POEMA NARRATIVO DE BERNARDO GUIMARÃES: A AMBIVALÊNCIA DO RISO EM “A ORIGEM DO MÊNSTRUO”
Authors: Melo Samuel Carlos , Sales José Batista de
Published: December 2017

Este trabalho investiga os processos de elaboração estrutural do poemas narrativo “A Origem do Mênstruo”, de Bernardo Guimarães. Além de Escrava Isaura (1875), o escritor mineiro teve relevante atuação como poeta, ignorada pela crítica. Nesse sentido, inicia-se pela exposição de sua situação controvérsia nos manuais de história da literatura, em que sua notabilidade está creditada, quase que exclusivamente, à atuação como romancista, passando pela exposição de aspectos gerais sobre sua produção em poesia, a situação em relação à poesia romântica de seus coetâneos, assim como a sua atuação como introdutor da poesia pantagruélica, produzida e figurada clandestinamente entre os estudantes da faculdade de direito do Largo São Francisco em São Paulo, entre as décadas de 1840 e 1850. Segue-se expondo os pressupostos teóricos para a análise, partindo da imersão dos poemas na longa tradição do poema narrativo, até a exposição de questões relativas ao tipo grotesco, especificamente as concepções de Victor Hugo (1802-1885) e Mikhail Bakhtin (1895-1975), para, por fim, efetuar análise do poema em questão.
“MAS TU DIZES PALAVRAS SEM SENTIDO / E ESQUECES-TE DE MIM” – OS LIMITES DA SUBJETIVIDADE TRÁGICA E DA ALTERIDADE FALHADA NO FAUSTO DE FERNANDO PESSOA
Authors: Xavier Rodrigo Alexandre
Published: December 2017

O presente texto busca apresentar traços da dialética-limite “eu-outro” na relação entre Fausto e Maria no poema dramático de Fernando Pessoa. Enquanto no Fausto de J.W. Goethe o amor se apresenta como um dos elementos redentores do herói trágico alemão, na obra de Fernando Pessoa ele pode ser compreendido como componente irrealizável, e por isso desencadeador do agravamento da crise existencial do Fausto português. A potência subjetiva do anti-herói pessoano se intensifica na medida em que sua capacidade de alteridade se esvazia no falhanço amoroso.
EU JOGO, EU JURO: LEITURAS DO PER-FORMA-TIVO EM PESSOA, HELDER E LLANSOL
Authors: Anglada Carolina , Sedlmayer Sabrina
Published: December 2017

A partir de uma breve discussão a respeito da insurgência de uma perspectiva performativa em Fernando Pessoa, o presente artigo objetiva propor um estudo comparativo entre a noção de poemacto em Herberto Helder e o drama-poesia de Maria Gabriela Llansol, evidenciando a que diferentes tarefas o uso poético da linguagem se vincula. Por meio das formulações desses dois escritores portugueses, discute-se também o entrelaçamento da forma-poesia com outros gêneros e outros procedimentos, evidenciando pontos de fuga para a questão da poesia no contemporâneo.
QUESTÃO DE PERSPECTIVA: O PONTO DE VISTA DO EU LÍRICO NA POESIA DE MURILO MENDES
Authors: Destri Luisa
Published: December 2017

Este artigo procura a caracterização específica da visualidade na poesia de Murilo Mendes. A fim de compreender os recursos que permitem a expressão do “olho armado” do poeta, discute poemas colhidos em diferentes momentos da trajetória, com interesse, principalmente, na atitude lírica do sujeito poético, que se mantém frequentemente como observador. A partir do emprego, nas análises, das ferramentas fornecidas por Emil Staiger e Wolfgang Kayser, sustenta-se que o ponto de vista do eu lírico seja uma categoria fundamental para o estudo da poesia de Murilo Mendes.
From the “Closed” to the “Open” Commercial State: A Very Brief History of International Economic Law
Authors: Schütze Robert
Published: December 2017

Commerce had become a “reason of state” in the eighteenth century. With the publication of Smith’s Wealth of Nations, the idea that free international trade was economically beneficial however gradually gained prominence. The long nineteenth century indeed saw timid – bilateral – attempts to implement the new politico-economic philosophy. Yet the First World War and the Great Depression destroyed almost all trade liberalisation already achieved, and the neo-mercantilist policies of the 1920s and 1930s seemed to turn the wheels of commerce backwards. Nonetheless: after the Second World War the belief that a peaceful world order could only be founded on a stable international economic order emerged strengthened; and a number of institutional attempts to liberalise – and harness – the world economy were immediately made, culminating in the creation of the 1947 General Agreement on Tariffs and Trade.
Lippia ganevii (Verbenaceae), a new combination for Lantana hatschbachii Moldenke, now validly published
Authors: SALIMENA FÁTIMA REGINA G. , MÚLGURA MARIA EMA , PASTORE JOSE FLORIANO BARÊA
Published: December 2017

A new combination for Lantana hatschbachii, earlier defectively published as Lippia ganevii, is provided. The species is currently known exclusively from the type locality in the municipality of Morro do Chapéu, Bahia, Brazil, in the rocky-field vegetation of the Chapada Diamantina. The species is characterized by oval-triangular to reniform leaves with a cordate to truncate base and lanceolate bracts covered by glandular trichomes.
Contribution to the knowledge of Chinese Phasmatodea V: New taxa and new nomenclatures of the subfamilies Necrosciinae (Diapheromeridae) and Lonchodinae (Phasmatidae) from the Phasmatodea of China
Authors: HO GEORGE WAI-CHUN
Published: December 2017

This study provides descriptions of one new genus, 24 new species and four new subspecies from the Necrosciinae and Lonchodinae of China. They are, Dianphasma sparsigranulatum sp. nov., D. yui sp. nov., Micadina songxiaobini sp. nov., Necroscia dianica sp. nov., Neohirasea fenshuilingensis sp. nov., N. hujiayaoi hujiayaoi sp. nov. & subsp. nov., N. h. shengtangshanensis subsp. nov., N. nanlingensis sp. nov., N. pengzhongi sp. nov., N. unispina unispina sp. nov. & subsp. nov., N. unispina parvula subsp. nov., N. wangpengi sp. nov., Oxyartes jinpingensis sp. nov., O. rubris sp. nov., Planososibia brevialata sp. nov., P. liui sp. nov., Pseudososibia cristata gen. nov. & sp. nov., P. undulatomarginata sp. nov., Sipyloidea tuberculata sp. nov., Carausius bicornis sp. nov., C. huanglianshanensis sp. nov., C. luchunensis sp. nov., C. novus sp. nov., C. yingjiangensis sp. nov., C. yunnanensis sp. nov. and Pericentrus biwenxuani sp. nov.; suggests seven new combinations for Neohirasea asper (Redtenbacher, 1908) comb. nov. from Paramenexenus Redtenbacher, 1908, Planososibia qiongensis (Ho, 2013) comb. nov. from Sosibia Stål, 1875, Pseudososibia brachyptera (Chen & He, 2004) comb. nov. from Sosibia with the first description of the female, Phraortes albopictus (Chen & He, 2008) comb. nov. from Dixippus Stål, 1875, Lonchodes gracicercatus (Chen & He, 2008) comb. nov. from Dixippus, Lonchodes guangdongensis (Chen & He, 2008) comb. nov. from Dixippus and Lonchodes paucigranulatus (Chen & Xu, 2008) comb. nov. from Dixippus; records Pericentrus Redtenbacher, 1908 for the first time in China. Key to the species and list of the species of the studied genera including Dianphasma Chen & He, 1997, Micadina Redtenbacher, 1908, Necroscia Audinet-Serville, 1838, Neohirasea Rehn, 1904, Oxyartes Stål, 1875, Planososibia Seow-Choen, 2016, Pseudososibia gen. nov., Sipyloidea Brunner von Wattenwyl, 1893 and Carausius Stål, 1875 are provided.
Two Leading ENSO Modes and El Niño Types in the Zebiak–Cane Model
Authors: Xie Ruihuang , Jin Fei-Fei
Published: December 2017

Modern instrumental records reveal that El Niño events differ in their spatial patterns and temporal evolutions. Attempts have been made to categorize them roughly into two main types: eastern Pacific (EP; or cold tongue) and central Pacific (CP; or warm pool) El Niño events. In this study, a modified version of the Zebiak–Cane (MZC) coupled model is used to examine the dynamics of these two types of El Niño events. Linear eigenanalysis of the model is conducted to show that there are two leading El Niño–Southern Oscillation (ENSO) modes with their SST patterns resembling those of two types of El Niño. Thus, they are referred to as the EP and CP ENSO modes. These two modes are sensitive to changes in the mean states. The heat budget analyses demonstrate that the EP (CP) mode is dominated by thermocline (zonal advective) feedback. Therefore, the weak (strong) mean wind stress and deep (shallow) mean thermocline prefer the EP (CP) ENSO mode because of the relative dominance of thermocline (zonal advective) feedback under such a mean state. Consistent with the linear stability analysis, the occurrence ratio of CP/EP El Niño events in the nonlinear simulations generally increases toward the regime where the linear CP ENSO mode has relatively higher growth rate. These analyses suggest that the coexistence of two leading ENSO modes is responsible for two types of El Niño simulated in the MZC model. This model result may provide a plausible scenario for the observed ENSO diversity.
Evolution, trends, outcomes, and economics of hematopoietic stem cell transplantation in severe autoimmune diseases
Authors: Snowden John A. , Badoglio Manuela , Labopin Myriam , Giebel Sebastian , McGrath Eoin , Marjanovic Zora , Burman Joachim , Moore John , Rovira Montserrat , Wulffraat Nico M. , Kazmi Majid , Greco Raffaella , Snarski Emilian , Kozak Tomas , Kirgizov Kirill , Alexander Tobias , Bader Peter , Saccardi Riccardo , Farge Dominique
Published: December 2017

Key Points

Using EBMT data in >2000 patients from 1994 to 2015, we analyzed the development and factors influencing outcomes of HSCT for ADs. Transplant center experience, accreditation, and national socioeconomic factors are relevant for outcomes and future health service delivery.
Pulmonary arterial hypertension: tailoring treatment to risk in the current era
Authors: Gaine Sean , McLaughlin Vallerie
Published: December 2017

Recent advances in the treatment of pulmonary arterial hypertension (PAH) have led to improved patient outcomes. Multiple PAH therapies are now available and optimising the use of these drugs in clinical practice is vital. In this review, we discuss the management of PAH patients in the context of current treatment guidelines and supporting clinical evidence. In clinical practice, considerable emphasis is placed on the importance of making treatment decisions guided by each patient's risk status, which should be assessed using multiple prognostic parameters. As PAH is a progressive disease, regular assessments are essential to ensure that any change in risk is detected in a timely manner and treatment is adjusted accordingly. With the availability of therapies that target three different pathogenic pathways, combination therapy is now the standard of care. For most patients, this involves dual combination therapy with agents targeting the endothelin and nitric oxide pathways. Therapies targeting the prostacyclin pathway should be added for patients receiving dual combination therapy who do not achieve a low-risk status. There is also a need for a holistic approach to treatment beyond pharmacological therapies. Implementation of all these approaches will ensure that PAH patients receive maximal benefit from currently available therapies.
The changing landscape of chronic thromboembolic pulmonary hypertension management
Authors: Madani Michael , Ogo Takeshi , Simonneau Gérald
Published: December 2017

For patients with chronic thromboembolic pulmonary hypertension (CTEPH), the current standard of care involves surgical removal of fibro-thrombotic obstructions by pulmonary endarterectomy. While this approach has excellent outcomes, significant proportions of patients are not eligible for surgery or suffer from persistent/recurrent pulmonary hypertension after the procedure. The availability of balloon pulmonary angioplasty and the approval of the first medical therapy for use in CTEPH have significantly improved the outlook for patients ineligible for pulmonary endarterectomy. In this comprehensive review, we discuss the latest developments in the rapidly evolving field of CTEPH. These include improvements in imaging modalities and advances in surgical and interventional techniques, which have broadened the range of patients who may benefit from such procedures. The efficacy and safety of targeted medical therapies in CTEPH patients are also discussed, particularly the encouraging data from the recent MERIT-1 trial, which demonstrated the beneficial impact of using macitentan to treat patients with inoperable CTEPH, including those on background therapy. As the treatment options for CTEPH improve, hybrid management involving more than one intervention in the same patient may become a viable option in the near future.
Complete genome sequence of esterase-producing bacterium Croceicoccus marinus E4A9T
Authors: Wu Yue-Hong , Cheng Hong , Huo Ying-Yi , Xu Lin , Liu Qian , Wang Chun-Sheng , Xu Xue-Wei
Published: December 2017

Croceicoccus marinusE4A9Twas isolated from deep-sea sediment collected from the East Pacific polymetallic nodule area. The strain is able to produce esterase, which is widely used in the food, perfume, cosmetic, chemical, agricultural and pharmaceutical industries. Here we describe the characteristics of strain E4A9, including the genome sequence and annotation, presence of esterases, and metabolic pathways of the organism. The genome of strain E4A9Tcomprises 4,109,188 bp, with one chromosome (3,001,363 bp) and two large circular plasmids (761,621 bp and 346,204 bp, respectively). Complete genome contains 3653 coding sequences, 48 tRNAs, two operons of 16S–23S-5S rRNA gene and three ncRNAs. Strain E4A9Tencodes 10 genes related to esterase, and three of the esterases (E3, E6 and E10) was successfully cloned and expressed inEscherichia coliRosetta in a soluble form, revealing its potential application in biotechnological industry. Moreover, the genome provides clues of metabolic pathways of strain E4A9T, reflecting its adaptations to the ambient environment. The genome sequence ofC. marinusE4A9Tnow provides the fundamental information for future studies.
Whole exome sequencing identifies a novel homozygous frameshift mutation in the ASPM gene, which causes microcephaly 5, primary, autosomal recessive
Authors: Bhargav Desaraju Suresh , Sreedevi N. , Swapna N. , Vivek Soumya , Kovvali Srinivas
Published: December 2017

Microcephaly is a genetically heterogeneous disorder and is one of the frequently notable conditions in paediatric neuropathology which exists either as a single entity or in association with other co-morbidities. More than a single gene is implicated in true microcephaly and the list is growing with the recent advancements in sequencing technologies. Using massive parallel sequencing, we identified a novel frame shift insertion in the abnormal spindle-like microcephaly-associated protein gene in a client with true autosomal recessive primary microcephaly.  Exome sequencing in the present case helped in identifying the true cause behind the disease, which helps in the premarital counselling for the sibling to avoid future recurrence of the disorder in the family.
Tuition reduction is the key factor determining tax burden of graduate students under the Tax Cuts and Job Act
Authors: Lawston Patricia M. , Parker Michael T.
Published: December 2017

Background: The proposed Tax Cuts and Jobs Act (H.R.1) has stirred significant public debate on the future of American economics.  While supporters of the plan have championed it as a necessity for economic revitalization, detractors have pointed out areas of serious concern, particularly for low- and middle-income Americans.  One particularly alarming facet of the plan is the radical change to education finance programs and taxation of students in higher education. 

Methods:  By analyzing actual income and tuition of a public and a private university student, as well as the ‘average’ graduate student, we investigated the effect of both the House and Senate versions of H.R. 1 on taxation of students of various family structures. 

Results:  Our findings indicate that taxable tuition would be the greatest contributor to graduate student tax burden across all four categories of filing status.  However, when tuition reduction is upheld or a student is on sustaining fees rather than full tuition, graduate students would realize decreases in taxation.

Conclusions:  Overall, we conclude that removal of tuition reduction would result in enormous tax burdens for graduate students and their families and that these effects are dependent not only on the status of the student in their degree program but also on their tuition and stipend, and therefore the institution they attend.
PERFIL EPIDEMIOLÓGICO DA HEPATITE B EM UMA REGIONAL DE SAÚDE EM RECIFE
Authors: Nicolau Silvio , Medeiros Amanda Siqueira de , Santos Marcella Cristine Alves dos , Montarroyos Jacqueline Simas
Published: December 2017

Introdução: hepatites virais são patologias originarias, na maioria das vezes, pela ação de diversos agentes etiológicos. Os vírus da hepatite possuem tropismo pelas células hepáticas e se manifestam com perfis epidemiológicos, clínicos e laboratoriais diversos. As hepatites são consideradas como fator complicador de saúde pública porque estão relacionadas ao elevado número de pessoas acometidas. Objetivo: apresentar a situação epidemiológica da hepatite B, relacionado ao perfil sociodemográfico da população na I Regional de Saúde de Pernambuco. Método: pesquisa epidemiológica, descritiva, de abordagem quantitativa, cuja fonte de dados foi o Sistema de Informação de Agravos e Notificação (SINAN) através da página eletrônica da base de dados do Departamento de Informática do SUS (DATASUS). Resultados: No período de 2011 a 2015 foram notificados e confirmados, 4867 casos de Hepatites Virais nas 12 Regionais de Saúde de Pernambuco, sendo na I Regional 988 contaminados pelo vírus B, a maioria homens de faixa etária entre 20 a 39 anos e residentes de área urbana. Quanto a via de infecção 875 casos foram ignorados ou não preenchidos. Conclusão: Fica demonstrado, portanto, a necessidade de ações de prevenção baseadas em educação em saúde para a população, além de monitoramento da situação vacinal e capacitações periódicas direcionadas aos profissionais dos serviços de saúde.
El cambio en los modelos del trabajo social en salud mental: del modelo rehabilitador al modelo social
Authors: Cazorla Palomo Josep , Parra Ramajo Belén
Published: December 2017

El modelo rehabilitador es en la actualidad el modelo rector de nuestra sociedad y del mundo de la atención de la Salud Mental. Este estándar exige al individuo que se adapte al medio, responsabilizándolo de sus limitaciones y rechazando la diferencia. Desde esta visión se transforma a la persona en un usuario o un consumidor de servicios, reforzándose la discriminación a partir de los ideales establecidos y los mecanismos de control institucionales.El trabajo social emerge, desde sus inicios, como una disciplina que reconoce las capacidades y las experiencias de las personas de forma singularizada, para facilitar que sean estas las protagonistas de sus relatos de vida. Es por ello, que en el ámbito de la Salud Mental uno de los principales propósitos es la descategorización de la diferencia que perpetua el estigma. Esta concepción se encuentra estrechamente unida al modelo social, perspectiva que concibe toda vida humana con las mismas condiciones de dignidad que el resto de la sociedad, que facilita a las personas con trastornos mentales el reconocimiento como ciudadanos con plenos derechos y deberes dentro de la sociedad en la que habitan.
Propriedades Psicométricas da Geriatric Social Work Competencies Scale II
Authors: Daniel Fernanda , Ferreira Jorge , Monteiro Rosa
Published: December 2017

Introdução: A Geriatric Social Work Competencies Scale II (GSWCS II) é considerada uma referência na avaliação de competências de Assistentes Sociais Gero. O estudo teve como objetivo examinar as propriedades psicométricas da GSWCS II numa amostra de assistentes sociais portuguesas que trabalham com pessoas idosas.Materiais e Métodos: A GSWCS II foi administrada conjuntamente com um pequeno questionário socioprofissional elaborado por nós. Foram inquiridas/os 543 assistentes sociais com média de idades de 33.05 (7.57 = DP), do sexo feminino (96.1%) e em funções de Chefia (72.5%).Resultados: A consistência interna foi elevada em todas as dimensões (α > .9). A escala apresenta correlações elevadas com todas as suas dimensões (> .85). A Análise Fatorial Confirmatória foi utilizada para testar o modelo, baseado em uma estrutura de cinco dimensões, o teste do Qui-quadrado de ajustamento (χ2/gl) = 3.129 apresentou adequado índice de ajustamento.Conclusão: A GSWCS II apresenta indicadores de ser uma escala válida e fidedigna.
AVALIAÇÃO DA IMAGEM QUE OS FRANCESES TÊM DO BRASIL COMO SEDE DE MEGAEVENTOS
Authors: Olivieri Giovanna Buischi Antunes , Giraldi Janaina de Moura Engracia , Ferreira Luciana Brandão
Published: December 2017

O Brasil recebeu grandes eventos nos últimos anos, como Jornada Mundial da Juventude, Rio+20 e especialmente megaeventos esportivos, como a Copa do Mundo de Futebol, e mais recentemente os Jogos Olímpicos de 2016. Baseado nesse contexto e na importância desses eventos, sobretudo para a imagem do destino que os recebe, esse estudo objetivou avaliar a imagem do destino turístico Brasil como sede de megaeventos. Para isso, foi realizada uma pesquisa quantitativa descritiva com aplicação de questionários eletrônicos com uma amostra de estudantes franceses. Após a coleta dos dados, uma análise fatorial exploratória e uma comparação de médias entre as dimensões resultantes foram realizadas. Os resultados indicaram que os estudantes franceses possuem uma imagem positiva do Brasil como sede de grandes eventos, sendo os “Pontos Turísticos” a dimensão de imagem de destino mais bem apreciada. Adicionalmente, verificou-se que gênero e experiência com o país não foram fatores que influenciaram as respostas da amostra.
COMPETÊNCIAS SÃO IMPORTANTES PARA AGENTES DE VIAGEM? UM ESTUDO EXPLORATÓRIO EM AGÊNCIAS DE PORTO ALEGRE
Authors: Santos Thais Bellenzier dos , Santos Ana Clarissa Matte Zanardo dos
Published: December 2017

O presente artigo busca compreender quais são as principais competências necessárias a profissionais atuantes na área de vendas das agências de viagens localizadas em Porto Alegre/RS. Para tanto, realizou-se uma pesquisa de natureza quantitativa, utilizando uma survey para coleta de dados. Dentre as cento e oitenta agências de viagens existentes em Porto Alegre/RS, foram recebidos 69 questionários respondidos. Para analisar os dados foram utilizadas a estatística descritiva, a análise fatorial, a correlação, o teste T e a Anova, conforme a natureza dos dados. Apesar de o construto utilizado na pesquisa apontar três dimensões para analisar as competências – Conhecimentos, Habilidades e Atitudes –, o estudo apontou cinco dimensões: Habilidade, Qualificação Técnica, Conhecimento Tácito, Atitude e Conectividade. Os resultados evidenciaram, também, que a formação do profissional é baseada na escolaridade, mas as suas vivências pessoais tornam cada profissional único. Os resultados apresentados mostram que o fator Habilidade é considerado o mais relevante sob o ponto de vista dos gestores.
Sixty Years On: How the Superpowers Could Have Avoided the 1956 Hungarian Revolution
Authors: Békés Csaba
Published: December 2017

Following the political transition in Hungary and in East-Central Europe in 1989-90 an archival revolution unfolded in the countries of the former Soviet bloc, including Russia after 1991. Thanks to this process, the previously taboo topic of the 1956 Hungarian Revolution has become one of the best researched events of the history of the Soviet Bloc by the time of the sixtieth anniversary of the events. This includes the international context of the revolt as well, which has been covered by scholars in Hungary and abroad based on multiarchival evidence.
The Memoirs of János Kádár’s Interpreter Vladimir Baikov: A New Source on Soviet Policy in 1956 Hungary
Authors: Stykalin Alexandr
Published: December 2017

Among the recently published historical sources which add important details to our image of the Soviet policy in Hungary in the weeks of the 1956 revolution and its suppression, the memoirs of Vladimir Baikov are among the most important.

Vladimir Sergeevich Baikov (1916–2001), born in Moscow, worked as journalist and editor of Radio Moscow (Vsesoyuznii radiokomitet) news programs in the late 1930s and early 1940s, until the attack of Nazi Germany against the USSR in June 1941. He knew English well and began work on a PhD thesis on Contemporary American Literature. The war between Nazi Germany and the USSR, however, led to significant changes in his career. He became a political instructor in the Red Army and, when World War II had ended in May 1945, he found himself in Hungary, where he stayed on for about two years as an official in the Soviet military administration. It can be assumed that there was a lack of interpreters and translators of Hungarian in the Soviet military in post-war Hungary as well as in the Soviet part of the Allied Control Commission. Hence, Baikov was charged with learning Hungarian and, thanks to his linguistic skills, he quickly succeeded. In the first chapters of his memoirs, he describes the situation in Hungary of 1945-1946, the months of the acute confrontation between the pro-Communist and anti-Communist forces, especially in the days of the parliamentary elections in early November 1945. These were to be the last free elections in Hungary up till the spring of 1990.
Tradução cultural e a obra de José María Arguedas
Authors: Cunha Roseli Barros
Published: December 2017

Segundo Thaïs Diniz (1999), toda tradução é uma tradução cultural. Por sua vez, Dora Sales (2002), ao tratar especificamente da produção de José María Arguedas, sustenta que o autor se coloca como um tradutor entre culturas e empreende uma busca por uma tradução cultural. À luz desse contraponto teórico e, ainda, com o embasamento de Cornejo Polar (1994), Moya (2007) e Berman (1985), abordamos a questão em registros de dois momentos específicos da história cultural da América Latina. O primeiro deles, na crônica de Guamán Poma de Ayala, que trata do episódio de Cajamarca, Peru, em 1532. No segundo, analisamos fragmentos do romance Los ríos profundos (1958), no qual Arguedas, segundo Sales (2002), adotaria diversos procedimentos de tradução para tentar suprir uma incompreensão que persiste no subcontinente latino-americano entre a oralidade e a escrita, promovendo o que ela considera uma tradução cultural. Por meio desses dois momentos da produção cultural latino-americana à luz de teóricos dos Estudos da Tradução, mas também de outras áreas afins, procuramos ampliar as reflexões sobre a tradução no subcontinente e, mais especificamente, sobre o que pode ser compreendido por tradução cultural na obra de Arguedas.
A tradução e o tradutor no Brasil
Authors: Rodrigues Cristina Carneiro
Published: December 2017

Neste trabalho, pontuam-se acontecimentos significativos para a tradução e o tradutor no percurso percorrido desde as importantes manifestações dos tradutores nos anos de 1930 até a consolidação dos Estudos da Tradução como campo de pesquisa em 2003, com a criação do primeiro programa de pós-graduação em Estudos da Tradução no Brasil.
Os Estudos da Tradução no Brasil
Authors: Silva Ana Julita Oliveira da , Esqueda Marileide Dias , Liparini Tania
Published: December 2017

Os Estudos da Tradução começaram a se desenvolver como disciplina acadêmica, em nível internacional, a partir da década de 1950. No contexto brasileiro, diversos autores apontam a década de 1980 como o período de construção identitária da disciplina, que culminou na institucionalização da pesquisa em tradução nas décadas posteriores. Neste trabalho, realizou-se um registro histórico da fundação e atuação da Associação Brasileira de Pesquisadores em Tradução – ABRAPT – a partir do levantamento bibliográfico, de documentos e de informações obtidas diretamente com os principais envolvidos com a associação. Ainda, partindo dos trabalhos de Frota (2007), Vasconcellos (2013), Rodrigues (2013) e Milton (2015), que abordam a temática dos Estudos da Tradução no Brasil sob uma perspectiva histórica, investigou-se a situação das pesquisas em tradução no país nas décadas de 1980 e 1990 e realizou-se o histórico de um dos fóruns de discussão fundamentais para o desenvolvimento da pesquisa na área: o Encontro Nacional de Tradutores. Baseando-se na afirmação de Milton e Martins (2010) de que existem áreas na historiografia da tradução pouco exploradas no contexto brasileiro e devido à escassa bibliografia e pouca documentação compilada sobre a ABRAPT e demais fóruns de discussão, este trabalho visa contribuir para a preservação da história da associação e para o mapeamento dos Estudos da Tradução no Brasil
El acuerdo cubano-americano y la diplomacia del papa Francisco
Authors: Mazzina Constanza , Gonzalez Cambel Manuela
Published: December 2017

El acuerdo celebrado entre Cuba y Estados Unidos en el último diciembre de 2014 por el que se acordó la reanudación de las relaciones entre ambos países, después de más de cincuenta años de interrupción, demuestra un cambio histórico y una oportunidad recíproca. El presente artículo hace un recorrido por las relaciones bilaterales en clave histórico-política para luego revisar los hechos que desembocaron en el acuerdo, teniendo en cuenta que este implicó una negociación compleja y el esfuerzo de una serie de actores heterogéneos. Entre los distintos actores, el artículo destaca la actuación del papa Francisco como posibilitador del acuerdo y constructor del puente del diálogo entre Obama y Raúl Castro. Finalmente se introduce y reflexiona acerca de los puntos aún controversiales para el avance de las relaciones bilaterales.
El límite entre la libertad de expresión y la incitación al odio: análisis de las sentencias del Tribunal Europeo de Derechos Humanos
Authors: García Santos María
Published: December 2017

La actual situación en Europa y el mundo occidental es en cierta medida un reflejo del conflicto latente entre el auge de los discursos de odio y la libertad de expresión. Fenómenos como la globalización y el aumento de la inmigración hacia Europa han generado una oleada de rechazo y ansiedad ante una realidad cambiante, sobre todo a causa de agravantes como la crisis de los refugiados y el terrorismo. Esta tendencia pone de manifiesto el debate acerca de los límites de la libertad de expresión en el continente, no en vano este derecho representa uno de los pilares fundamentales de las democracias europeas. Así pues, este artículo analiza el estado del debate en el seno de las instituciones regionales, a través de varias sentencias del Tribunal Europeo de Derechos Humanos, con el fin de ilustrar el presente tira y afloja entre la libertad de expresión y la limitación del discurso de odio.
Entscheidungshilfe: Transdisziplinäre Forschung trägt zum Gelingen der Energiewende bei
Authors: Quitzow Rainer , Renn Ortwin
Published: December 2017

Das Kopernikus-Projekt Energiewende-Navigationssystem (ENavi) will robustes Wissen für die Entscheidungsfindung im Rahmen der Energie wende bereitstellen. Damit dies gelingt, erarbeitet das ENavi-Team Politikvorschläge, indem es interdisziplinäres Systemwissen
in einem transdisziplinären Bewertungsprozess mit dem Praxiswissen von Akteuren aus Politik, Wirtschaft und Zivilgesellschaft zusammenführt.
All Metals Age: Die postfossile Gesellschaft braucht alle Elemente des Periodensystems
Authors: Held Martin , Schindler Jörg
Published: December 2017

Reaktion auf zwei Beiträge zum Thema Rohstoffversorgung für die Energiewende in GAIA
Der Aufstieg Donald Trumps - zwischen Herrschaft und Widerstand
Authors: Wallmeier Philip
Published: December 2017

Reaktion auf drei Beiträge zum Thema Macht in Umweltpolitik und Umweltforschung in GAIA
Effect of target color and scanning geometry on terrestrial LiDAR point-cloud noise and plane fitting
Authors: Bolkas Dimitrios , Martinez Aaron
Published: December 2017

Point-cloud coordinate information derived from terrestrial Light Detection And Ranging (LiDAR) is important for several applications in surveying and civil engineering. Plane fitting and segmentation of target-surfaces is an important step in several applications such as in the monitoring of structures. Reliable parametric modeling and segmentation relies on the underlying quality of the point-cloud. Therefore, understanding how point-cloud errors affect fitting of planes and segmentation is important. Point-cloud intensity, which accompanies the point-cloud data, often goes hand-in-hand with point-cloud noise. This study uses industrial particle boards painted with eight different colors (black, white, grey, red, green, blue, brown, and yellow) and two different sheens (flat and semi-gloss) to explore how noise and plane residuals vary with scanning geometry (i.e., distance and incidence angle) and target-color. Results show that darker colors, such as black and brown, can produce point clouds that are several times noisier than bright targets, such as white. In addition, semi-gloss targets manage to reduce noise in dark targets by about 2–3 times. The study of plane residuals with scanning geometry reveals that, in many of the cases tested, residuals decrease with increasing incidence angles, which can assist in understanding the distribution of plane residuals in a dataset. Finally, a scheme is developed to derive survey guidelines based on the data collected in this experiment. Three examples demonstrate that users should consider instrument specification, required precision of plane residuals, required point-spacing, target-color, and target-sheen, when selecting scanning locations. Outcomes of this study can aid users to select appropriate instrumentation and improve planning of terrestrial LiDAR data-acquisition.
Preparation of poly(L-lactide)/poly(ethylene glycol)/organo-modified montmorillonite nanocomposites via melt intercalation under continuous elongation flow
Authors: Wu Ting , Yuan Ding , Qu Jin-Ping
Published: December 2017

An innovative eccentric rotor extruder (ERE), which can generate continuous elongation flow, was used to prepare the poly(L-lactide) (PLLA)/poly(ethylene glycol) (PEG)/organo-modified montmorillonite (OMMT) nanocomposites. The morphology was characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM), and showed that the OMMT nanoparticles were uniformly dispersed in the matrix and mainly existed in intercalation mode. The influence of OMMT on the rheological behavior of plasticized PLLA was investigated by dynamic rheological measurements, showing greater improvement of rheological properties compared to that of PLLA/PEG blend. The crystallization behavior and crystalline structures were studied by differential scanning calorimetry (DSC) and XRD, respectively, and showed that the presence of OMMT further speeds up the crystallization rate of plasticized PLLA. However, the crystallization rate and crystallinity had a slight downward trend at high OMMT content because of the inhibition effect of the OMMT percolation network structure. Polarizing optical microscopy (POM) was further carried out and proved that the OMMT nanoparticles as a heterogeneous nucleating agent can increase the spherulite growth rate and nucleation density. The thermal stability was investigated by thermogravimetric analysis and indicated that the addition of OMMT at low concentration can improve the thermal stability of plasticized PLLA more effectively.
La corrélation : ontologie et méthodologie
Authors: Gounelle André
Published: December 2017

The concept of correlation is not just a theological approach. It corresponds to Tillich’s ontology which is a “self transcendent realism”: realism since God is in the world; self-transcendent because He is not the world. In the world there is more than just the world. For us, God is at once intimate and stranger. The correlation method expresses this ontological bipolarity.
Auf dem Weg zur Methode der Korrelation
Authors: Sturm Erdmann
Published: December 2017

In my essay I try to show how both Tillich‘s concept of correlation and his method of correlation have developed since the 1920’s. My thesis is: In his lectures on Advanced Problems in Systematic Theology (1936-38) Tillich argues that the doctrines of Christian faith must be interpreted as answers to questions, implied in man’s existence. He is starting, however, with the theological concepts (revelation, God, Christology, Kingdom of God). This is the position (against dialectic theology) he already holds in his German period. The decisive about-turn is the logical and methodical conclusion to transform the answeringquestioning- scheme into a questioning-answering scheme and to make it the backbone of the structure of his Systematic Theology.
Theology, Culture, and Crisis: Tillich’s Method of Correlation and the Black Lives Matter Movemen
Authors: Rothchild Jonathan
Published: December 2017

I argue that Tillich’s early articulation of his method of correlation establishes a foundation that remains continuous throughout Tillich’s mature development of the method. Though susceptible to criticisms, Tillich’s method of correlation helps lay a groundwork for a dynamic theology of culture that can inform current responses to racialized violence and serve as a useful interlocutor with womanist theologians and the Black Lives Matter movement. I aim 1) to redress tendencies of scholars to underappreciate continuities between Tillich’s early and later writings and 2) to demonstrate that Tillich’s method of correlation remains relevant for contemporary crises that challenge theological and cultural imaginations.
Wide Existential Questions: A New Materialist Approach to the Method of Correlation
Authors: Pryor Adam
Published: December 2017

This chapter examines how Paul Tillich’s method of correlation is challenged but potentially compatible with the questioning of binaries that occurs in new materialism. In particular it examines how Karen Barad’s agential realism, and its primordial ontological unity of the ‘phenomenon’ understood as a relation without relata, disrupts the axiomatic reliance on a distinction between self and world that underpins the method of correlation specifically and many forms of correlational theology more generally. Giving weight to Tillich’s broad understanding of existentialism and its potential connection to his account of theonomy provides a way forward that gives credence to the ‘intra-action’ that has become critical to many forms of posthumanism and new materialism.