bluuebunny/crossref_metadata_2025 huggingface dataset:
Criteria of Monitoring the Activity of Innovative Secondary Schools: Acmeological Approach
Authors: Levkivska K.
Published: May 2023

The paper presents an analysis of the scientific literature to determine the theoretical assumptions of research values of innovation in education. The research deals with the system criteria of monitoring innovative secondary schools. This system of criteria is interpreted as a set of interdependent scales of acmeological evaluative principles of the educational institutions that reflect the ideal model of interaction of innovative secondary schools and modern values education. In the basis of the analysis the organizational structure of secondary schools (subject, object, object, condition and product) are brought into light to ensure the expected results of education. The key trends in the design of monitoring criteria of innovative secondary schools are identified in the scientific literature. The highlighted differences in approaches to the evaluation of innovative secondary schools and criteria of tracking the results of their activities require the determination of common fundamental provisions of monitoring the current state of value principles of innovative secondary schools in Ukraine. The scientific methods of analyses, synthesis, description and comparison have been used to single out the main trends of forming criteria for monitoring the innovative secondary schools.
Methods of Self-Conducting and Choral Skills of Music Students at Educational Institutions
Authors: Lysenko M.
Published: May 2023

The problem of self-regulation of professional activity of future teacher of music is shown in the article. The development of self-organizing organizes the academic work of students, equipping abilities of independent tasks to build his conducting and choral skills. Self-regulation is interpreted as the ability of the individual to see the ultimate goal of its activities independently find a rational way to achieve and implement, manage their operations and as that meets today's requirements.

The phenomenon is considered the highest degree of identity when the acquired skills and achieve perfection turned into skills, and the sequence of their execution is carried out automatically. Self-regulation is the desire and ability to bring the professional training to the end, overcome difficulties through self-discipline, self- control, self-belief, self-esteem. The author of the article states that the task of the teacher is to manage the process of self-student directing his actions intellectual and cognitive areas through its self-regulation skills. The work advocates the idea that this process can be successful under the following conditions: when the individual can adequately display and simulate learning situations; transform their own internal and external activities, in accordance with state academic content and situations; do wilful efforts to overcome difficulties and achieve the desired professional goals.
Music and Сreative Potential of Future Teachers in the Context of Intersectoral Integration
Authors: Oliinyk S.
Published: May 2023

In this article the idea of music-creative potential of future teachers in the context of intersectoral integration was grounded for the first time. The study of the physiological nature of emotions allows the teacher to use a musical-therapeutic effect in his work. Based on this the experience of physicians on the use of music therapy in the field of preventive and regenerative medicine was analyzed. It was noted the widespread use of music in the work of psychologists with such issues as: correction of emotional stress, mental disorders in all ages, normalization of the mental state of children with disabilities. It was proved an importance of understanding of physiological causes of emotions by teacher during hearing of music and improvisation in work with children. correction and mental development of child occurs through of creativity. It was proved that folklore is the most accessible material for children's creation.

The folk song contains natural variations of musical development, for this reason folklore is available for improvisation. In this way, the practical realization of musical-creativity manifested on musical-therapeutic level of teachers activity. Due to the current difficult realities such as: economic difficulties, unstable political interests, conflict in the east of Ukraine, informational oversaturation of society, changing moral values, etc research interests of musicians-teachers have increased significantly.

The teacher of music, which is usually educate in children a love of music, formed aesthetic taste and ideals, for now takes note their mental health. This way, nonverbal language of music is the only factor in improving the psychological impact of child.

Leading musical teachers define music-therapy as technology for personal development.
Dual-band bilayer metasurfaces enabling platforms for independent polarization sensitive/insensitive modulations
Authors: Lu Jie , Wang Shuai , Meng Yanzi , Zang Guizhi , Xia Shengxuan , Shang Xiongjun , Wang Lingling , Zhai Xiang
Published: May 2023

We propose a design of bilayer metasurfaces, imposing arbitrary and independent phase profiles on arbitrarily polarized beams at λ
1 = 505 nm and circularly polarized beams at λ
2 = 633 nm. The method cascades two layers that separately function as convertible waveplates and full-wave plates for modulation of polarization and phase. We investigate the performances of the asymmetric deflector and multi-foci metalenses. Specifically, polarization-independent deflector or single-focus metalens can be achieved at λ
1, while polarization-dependent deflector or dual-foci metalens are designed at λ
2. We demonstrate a simple yet effective approach interconnecting phase distributions and flexible polarization responses, which holds great promise in information multiplexing and security.
PENGEMBANGAN APLIKASI TEMPAT PENGOLAHAN SAMPAH BERBASIS ANDROID MENGGUNAKAN MODEL EXTREME PROGRAMMING DAN BLACK BOX TESTING
Authors: Lampung Pramayota Fane'a , Pratama I Putu Agus Eka
Published: May 2023

The closure of the TPA, which had been operating since 1990, forced Gunaksa Village to have its own TPST or Local Waste Processing Site (TOSS) as a waste processing site. The Klungkung regency government also requires each village to process household waste independently. This policy obliges Gunaksa Village to have its own (TOSS) as a waste processing site. According to Law No. 18 of 2008 concerning waste management, it is necessary to change the pattern of waste management which is based on reducing and handling waste. The output of this research is in the form of a local waste management application that can help TOSS in Gunaksa Village, Klungkung Regency which is expected to be able to integrate the management of each division and level so that it runs effectively and efficiently. This application is intended as a recording system in the management of waste banks. Research will be conducted using the methodextreme programming. The system will be designed using the Unified Modeling Language (UML). System testing will use the Black Box method. The results of the black box test state that the input and output of the Gunaksa Bank Garbage Application (GUNABANGSA) are appropriate.
PERANCANGAN SISTEM INFORMASI EVALUASI PASCA PELATIHAN KESEHATAN DI KEMENTERIAN KESEHATAN
Authors: Ricaesar Nopianto , Siregar Kemal Nazaruddin
Published: May 2023

The industrial revolution and the current era of information technology have touched various fields, including health. Competency development of health human resources is something that must be done to be able to adapt in the era of the industrial revolution 4.0. In an effort to develop the competence of Health Human Resources, training is a form that is commonly carried out today. Post-training evaluation is a form of training evaluation to determine the effectiveness of a training so that training can be continuously modified to achieve the best effectiveness. Evaluation of post-health training is currently still done manually, which causes not all health training to be evaluated because it requires a lot of resources and budget. The use of information technology in conducting post-training evaluations can be a solution to existing problems. The post-health training evaluation is carried out by developing an information system for the post-health training evaluation that can be carried out quickly, precisely and massively. The purpose of this research is to design an evaluation information system after health training to the system design stage. The development method uses the System Development Life Cyle (SDLC) with the waterfall model until the system design stage. System design is done by making context diagrams, ERD, TRD, Data Dictionary, Flow Chart and DFD. The design of this information system is expected to be the basis for the development of a more comprehensive health EPP information system in the future.
RANCANG BANGUN SISTEM INFORMASI EVALUASI PENYELENGGARAAN PELATIHAN BIDANG KESEHATAN BERBASIS WEB
Authors: Hidayat Irfansyah Maulana , Utomo Budi
Published: May 2023

Evaluation is carried out to determine the effectiveness of the training. Evaluations that are still carried out manually/conventionally by collecting data through filling in instruments, have constraints including; Speed of submission of evaluation results report; delay in submitting the issuance of a certificate because the results of the report are used as a requirement for filing; limited storage space for files/report archives; risk of damage, loss of data either caused by viruses, dysfunction of device operations or accidental factors in deleting files. For this reason, a system is needed that can help and facilitate the evaluation process starting from recording, storing and reporting. System development was carried out using qualitative research methods and input-process-output system development methods using the steps of the System Development Life Cycle (SDLC) method of the prototype model. The PIECES Framework is used to analyze system requirements to produce user satisfaction levels. The results of the research are the design of a system consisting of Context Diagrams, Entity Relationship Diagrams (ERD), Table Relational Diagrams (TRD), Standard Operational Procedure (SOP) Flow Diagrams and Data Flow Diagrams (DFD). Users of this system are Admin (program person in charge), Assessors, Organizers and Leaders. This information system is able to facilitate the process of implementing and reporting the results of evaluation implementation, ease of accessing and presenting reports, providing data storage space and better data management compared to conventional methods.
PERBANDINGAN METODE BALANCED SCORECARD DAN NAÏVE BAYES DALAM PREDIKSI DAN REKOMENDASI PADA PENILAIAN KINERJA GURU (STUDI KASUS : SMK YADIKA 12 DEPOK)
Authors: Kurniawan Zaqi , Indra
Published: May 2023

Teacher Performance Assessment guarantees a quality learning process at all levels of education. Educational supervision will be carried out with the aim to improve the quality of teaching / teacher so that the competitiveness of students studying at the school will increase towards a better direction. Supervision assessment is a class visit technique to obtain data about the actual situation regarding the ability and skills of teachers in teaching and mastery of class. To determine the teacher's performance, one approach can be done using the Balanced Scorecard approach and Naïve Bayes classification. The determination of teacher performance is then processed using Analytic Network Process-based modeling to improve teacher evaluation criteria that are still low. With the help of Super Decision software, a decision support system was created in determining teacher performance. The results of this study are the recommendations of permanent teachers in Junior High Schools, High Schools, and Vocational Schools Yadika 12 Depok based on performance to be objective and make more efficient decisions.
PEMBANGUNAN COMPILER DOMAIN SPECIFIC LANGUAGE SEBAGAI GENERATOR FORM HTML MENGGUNAKAN PYTHON SLY
Authors: Adiyoso Wibisono , Susetyo Yeremia Alfa
Published: May 2023

The rapid development of information technology has a significant impact on the way companies operate. Companies can utilize technology to simplify and accelerate their business processes, including recording and managing transactional data. PT XYZ is one of the largest retail companies, with a vast amount of data and requiring various types of different HTML forms. Therefore, standardization in program code writing is necessary to minimize errors and facilitate application maintenance. This research aims to build a Compiler Domain Specific Language (DSL) as a web-based HTML form generator for PT XYZ. The study uses the Python SLY library, passing the Lexer and Parser processes in DSL development. The result of this research is a web-based HTML form generator that facilitates developers in creating standardized and automatic HTML forms. The use of DSL can speed up the program code writing process, minimize errors, and create structured and easily understood code by developers.
RANCANGAN SISTEM INFORMASI MONITORING DAN EVALUASI KIT SANITARIAN PUSKESMAS
Authors: Maulida Dwita , Prabawa Artha
Published: May 2023

Environmental health inspection is part of the environmental health services carried out by the Public Health Center. Environmental health inspections are carried out by observing environmental media using the health center's sanitarian kit to measure the quality of water, air and food. The District/City Health Office is expected to assist the Public Health Center in providing a sanitarian kit as a tool to support environmental health inspections. The Public Health Center that already have a sanitarian kit, need to carry out item management which includes monitoring and evaluating the use of the equipment. Based on this, the design of a monitoring and evaluation information system for the health center sanitarian kit using the Systems Development Life Cycle (SDLC) method with a prototype approach was created. System design stages start from planning, analysis, to design. The end result of this information system is to obtain information related to the utilization of the kit, the condition of the equipment, the obstacles encountered, to the maintenance of the equipment (calibration, availability of reagents and spare parts) which can then be utilized by the District/City Health Office and the Ministry of Health.
ANALISIS KLASIFIKASI SENTIMEN PENGGUNA MEDIA SOSIAL TWITTER TERHADAP PENUNDAAN PEMILU PRESIDEN TAHUN 2024
Authors: Jimmy  , Hermaliani Eni Heni , Kurniawati Laela
Published: May 2023

The discourse of postponing the 2024 election and extending the term of office of the president has stimulated sentiment in some regions in Indonesia. The discourse has implications for the extension of the president's term of office which is considered unconstitutional. The issue of postponing the election is clearly not the aspiration of the people, but only the interests of political passion and lust among the rulers who want to perpetuate power so that it is considered to violate and insult the constitution which stipulates that elections are held every five years. This study aims to determine how to analyze the sentiment of postponement the 2024 election on comments from the Indonesian people on Twitter or called tweets. The number of comments that will be used in the study is 1826 consisting of 710 positive sentiments and 1116 negative sentiments. The research method used is the Cross-Industry Standard Process for Data Mining (CRISP-DM) method. With this method, the stages of research carried out are data collection, business understanding, data understanding, data preprocessing, data labeling, modeling, evaluation, and deployment. Based on the results obtained at the modeling stage, the tweet data that has been collected is then processed and analyzed for sentiment with a train/test split data model and k-fold cross validation using the Naive Bayes (NB) algorithm, Support Vector Machine (SVM), Deep Learning (DL) ), and Desicious Tree (DT) and a comparison of 80:20 for training and testing data, the highest accuracy value is obtained by using the train/test split data model using the Naive Bayes algorithm to produce an accuracy of 80,55%.
PROTOTYPE SISTEM INFORMASI BIMBINGAN DAN KONSELING MENGGUNAKAN FIGMA
Authors: Putri Ranti , Widya Rika , Yusman Yanti
Published: May 2023

Guidance and counseling services are one of the efforts that must be held in schools to facilitate the development of students both individually and in groups. Currently there are still a number of schools that still provide conventional guidance and counseling services, where counseling services are still carried out offline (face to face) in the school counseling room. With the implementation of such guidance services and the identicality of the counseling room with students who have problems, students who are called or come to the counseling room get a negative opinion from other students. Even though counseling services in schools do not only deal with students who have problems, but counseling services in schools can be a facility that can be used by students to carry out guidance (academic, talents, interests, potential) and counseling (activities carried out by counselors (counseling teachers) and students with the aim of providing solutions and helping solve problems faced by students). For this reason, it is necessary to utilize technology so that counseling services can be carried out digitally. This research focuses on making a prototype guidance and counseling information system. Prototypes are made using figma with the aim of getting user experience. User experience is needed so that when the guidance and counseling information system is built it can suit the needs of the school.
PERANCANGAN SISTEM INFORMASI PENGARSIPAN BUKTI TRANSAKSI PEMBAYARAN BERBASIS WEB DI PT NUSANTARA TURBIN DAN PROPULSI
Authors: Muharram Agung , Muthmainnah  , Sufyana Candra Mecca
Published: May 2023

PT Nusantara Turbine and Propulsion is a company engaged in the maintenance, repair and overhaul (MRO) of gas turbines on an airplane engine. The research conducted to design Payment Transaction Proof Filing Information System at PT Nusantara Turbine and Propulsion with the aim of producing a web-based application that plays a role in digitally collecting documents that were previously done manually. The research method for developing these applications uses SDLC (Problem identification, Data analysis, Design, Testing, Implementation, and Maintenance) & UML. This web application uses MYSQL & APACHE as a local server and is created using PHPRAD. UML plays a role in representing the workflow of a system.  The result of this research is a web-based proof of payment transaction archiving application that aims to make it easier for workers when archiving, such as searching and storing documents so that it can be done digitally.
PERANCANGAN SISTEM INFORMASI AKUNTANSI PERSEDIAAN BAHAN BAKU DAN BARANG JADI PADA PT. SMU
Authors: Rahma Hanum Yustisia , Abdussalaam Falaah
Published: May 2023

PT. SMU is a manufacturing business company that produces foods such as cheese. The research conducted found problems with the manual process that is still used to record the inventory of raw materials and finished goods so that the recording process is less effective. The purpose of this design is to create a computerized system to record the inventory of raw materials and finished goods at PT. High school quickly and precisely. The research technique uses qualitative methodology with tools to collect data through observation, interviews and literature review. The waterfall approach is used to develop the software and the stages involved including Flow map, Context Diagram, Data Flow Diagram and Entity Relationship Diagram are then implemented using Microsoft Visual Studio 2012 using Microsoft Access 2019 as a database. The results of the research conducted that with the existence of an accounting information system for raw material and finished goods inventory at PT. SMU can ease the work of employees in inputting raw material and finished goods inventory quickly and more effectively.
PERSPEKTIF REMAJA PEREMPUAN KOTA MEDAN TERHADAP FITUR FD TALK “APLIKASI FEMALE DAILY”
Authors: Nasution Elza Hasyim , Sazali Hasan
Published: May 2023

In today's digital era, teenagers have the convenience of learning new things and following beauty trends through various available platforms and media. One platform that is presented to be able to follow beauty trends is Female Daily. This study aims to analyze the perspectives of young women in the city of Medan on the FD Talk feature on the Female Daily application. The research method used is qualitative research using in-depth interview techniques with 3 sources of informants who actively use FD Talk. Data collection techniques were carried out through observation and interviews of young women in the city of Medan. The analysis was carried out using the theory of TAM to understand user perceptions about usability, ease of use, and attitudes toward using the application and also using interpersonal communication theory. The results showed that the features of FD Talk succeeded in building positive perceptions of usability and ease of use in the eyes of the users. The speakers found it useful to learn about skincare and beauty from the personal experiences of other users on the platform. In addition, a good and easy-to-understand interface is also a factor that makes users feel comfortable using the application.
Pendampingan Sertifikasi Halal Gratis bagi Pelaku Usaha Mikro dan Kecil di Kabupaten Tanjung Jabung Timur
Authors: Sampoerno Mohd. Norma , Saadah Maratun , Irawan Turino Adi , Hardi Sean Popo , Budianto Achyat
Published: May 2023

The process of digitizing halal certification turns out to be quite difficult for business actors who are not familiar with using computers. Moreover, it takes a long time to fill out the entire form, micro and small business actors who do not have employees prefer to open a business or operate as usual rather than spending time studying a series of certification processes. Therefore, the writing team as halal assistants feel the need to carry out community service in the form of assistance in filling out forms (SJPH). Based on the results of the dedication that has been carried out, it can be said that the service activities have been successful, business actors understand the importance of halal certificates, consciously and willingly attend the mentoring event to gain technical knowledge of processing halal certificates. Business actors are also willing to make improvements when during the filing period a discrepancy is found by the fatwa commission which must be corrected by the business actor.
Implementasi Sistem Informasi Pencatatan Laporan Tahfiz pada Yayasan Majelis Hifzhu Syifaa Cileungsi
Authors: Gunawan Dedi , Mora Hakim , Husein  , Hafidzurrahman Abdullah Fathan , Berliani Safira
Published: May 2023

This article discusses the implementation of the website based Tahfiz Report Recording Information System application at the Assembly Hifzhu Syifaa Cileungsi Foundation because of community service activities. The main purpose of implementing this application is to make it easier for the Foundation to manage and record the students' memorization reports. This website-based application allows teachers to easily enter grades and notes related to students' memorization through the application, thereby speeding up the recording and assessment process. This application can be accessed via a web browser, providing access flexibility for users. In application development, special attention is paid to a simple user interface to make it easy for novice users to use. The research method used is descriptive qualitative with data collection through questionnaires and research. The development technique applied is Prototype, where application functions are tested with relevant input. The results of this implementation present a website based Tahfiz Report Recording Information System application as a practical solution for the Assembly Hifzhu Syifaa Cileungsi Foundation in managing rote reports. It is hoped that this application will provide significant benefits and can be adopted by foundations or similar institutions that require an effective and efficient tahfiz report recording system.
Relationship between Family Health Behavior with Improving Patient Functional Capacity Post Stroke in the Dwikora Area
Authors: Singarimbun Ristika Julianty
Published: May 2023

Stroke is the biggest disease that causes paralysis of the limbs. Stroke patients require comprehensive treatment, including long-term recovery and rehabilitation efforts, even for the rest of the patient's life. The family plays an important role in this recovery phase, so from the start of treatment the family is expected to be involved in patient care. Family knowledge in the care of post-stroke patients is very important to be able accelerate the independence of post-stroke patients. This study aims to analyze the relationship between family health behavior and increasing the functional capacity of post-stroke patients in the Dwikora Area. The research was conducted in October 2021 - February 2022 the type of research is cross sectional. The study population was a family of post-stroke patients, totaling 30 people. The sampling technique used total sampling. Data collection in the study was carried out by distributing questionnaires directly to families. The statistical test used is the spearman rank. Based on the results of research conducted in the Dwikora Region, the majority of family knowledge in increasing the functional capacity of post-stroke patients was sufficient, 15 people 56.7%, both 13 people 43.3% and less than 2 people 6.7%. The attitude of the family in increasing functional capacity after stroke was a good majority of 15 people 50%, quite a number of 11 people 36.7% and less a number of 4 people 13.3%. Family action in increasing unctional capacity after stroke is sufficient for the majority of 17 people 56.7%, good for 11 people 36.7% and less for 2 people 6.7%, It is hoped that the family will carry out its role by increasing knowledge, attitudes and actions, so that the patient can independently carry out his own activities.
Study of the Impact of Side Effects of Using Off-Label Drugs in Patients with Systemic Lupus Erythematosus on Health Costs
Authors: Yuwindry Iwan , Yusri  , Tangkas Hansel Hens
Published: May 2023

The main problem in conducting lupus treatment is that most drugs for the therapy provided have not been authorized so that they are still included in the class of off-label drugs for the treatment of lupus. The use of off-label drugs can carry the potential for side effects in Lupus patients which have an impact on increasing health costs. This study aims to determine the impact of side effects of using off-label drugs on health costs in lupus patients, as an integrated evaluation in seeking to improve the quality of life and ensure proper care in Lupus patients. This study was conducted using a cross-sectional method by means of a survey using the Naranjo Algorithm instrument (PESO Book) to determine the incidence rate of side effects that exist in LSE therapy using off-label drugs and calculate the health costs of lupus patients. The results showed that the most respondents were in adulthood (19 respondents or 47.5%), then the most respondents were female (37 respondents or 92.5%). Data on the incidence of side effects obtained the most respondents in the Probable category (most likely to occur ROM) of 14 respondents or 35%. In addition, data on health costs incurred by more respondents experienced an increase, namely 23 respondents or 57.5%. The research data shows the calculated r value is 0.3044 and the Sig (2-tailed) value is 0.000 with a confidence level (CI) of 0.05. The results of the analysis clearly show that there is a significant relationship between the side effects of using off-label drugs on the health costs of lupus patients, in this correlation there is a unidirectional relationship, where if the value of side effects experienced by respondents is high, the value of respondents' health costs is also high.
DISSEMINATED ASPERGILLOSIS -A CASE REPORT
Authors: Suresh A.T. Varnana , E. K Arjun , Vernekar Akshada , C. Kakodkar Uday
Published: May 2023

Aspergillosis is a fungal infection of the lungs, caused by the genus Aspergillus. Aspergillomas form in cavities found within the lungs formed from previous lung disease and can infect other tissues such as skin, sinuses or become disseminated throughout the body. Disseminated aspergillosis develops in severely immunocompromised patients, the critically ill patients and patients on steroids. The present case highlights the importance of early detection and prompt treatment of disseminated aspergillosis with antifungal therapy which if not treated promptly could prove fatal to the patient. The patient responded very well to the treatment and showed clinical, radiological improvement and microbiological clearance.
EVALUATION OF BIOCHEMICALAND HEMATOLOGICAL PARAMETERS IN MACROCYTIC ANEMIA
Authors: Avaru Akib , Sudhakar Shubha , C K Rao Anuradha
Published: May 2023

Background: In the age of calibrated automatic analysers, biochemical and hematological parameter evaluation form the yardstick to dene macrocytic anemias. The size of red cells in relation to mean corpuscular volume (MCV) has been used to categorize anemia. Aim of current study was to evaluate the role of routine blood parameters and biochemical parameters in differentiating megaloblastic anemia and non megaloblastic anemia. Methods:Aretrospective study was carried out on retrieved records (laboratory parameters) of the patients who were admitted at a tertiary care hospital, this included a total of 90 cases of anaemia between January 2020 - July 2021. These included records of patients with anaemia based on Vitamin B12 levels, LDH levels. Other various parameters like mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration were also taken into consideration for descriptive statistics. Results: Liver disease was the most common cause of macrocytosis (40%). The other causes in decreasing order of frequency were megaloblastic anaemia (27.7%), hemolytic anemia (8%), drug induced (9%).When comparisons of various complete blood count parameters between megaloblastic and non-megaloblastic group was done with LDH having signicance (p=0.001) in megaloblastic group and .011 in non-megaloblastic group. Conclusions: Evaluation of Methyl malonic acid and homocysteine levels, is sensitive, but expensive and scarcely available. The overall performance which is measured using Area under the Curve indicates that a contribution of LDH and MCV are good at differentiating megaloblastic Vs. Non megaloblastic causes of macrocytic anemias, However a larger population should be studied to nd variances between ethnicity, gender and age
PREVALENCE OF NODAL METASTASIS ASSOCIATED WITH DECREASED EXPRESSION OF CYTOTOXIC CD8+ T LYMPHOCYTE IN P53 COLO-RECTAL CARCINOMA IN SOUTHERN ETHNICS OF TAMIL NADU
Authors: K Shantharaman , S Gurusamy , Mari. R Chandhru , Ilambirai M Ramasundari , Kala. K Chandra
Published: May 2023

Colorectal Cancer (CRC) is one of the most common cancers in the world. The most frequent mutated p53 tumour suppressor gene predisposes resistance to therapy, resulting in poor prognosis in this disease. Our study aimed to evaluate the expression of CD8+lymphocytes in mutant p53 CRCs and to nd out its correlation with other tumour related aggressive parameters like tumour size, site, nodal status etc. This study was conducted at Department of Pathology, Tirunelveli Medical College, Tamil Nadu, India. In this study 51 patients with colorectal cancers were included. Age at diagnosis, gender, tumour site, tumour size, tumour margin, tumour grade, histological type, depth of invasion, tumour budding, vascular and neural invasion were analysed. An Immunohistochemical study was done for the p53 mutation gene, and quantication of Cd8 lymphocytes. Among the 38cases with mutant p53 gene, high CD8 score was seen in 14 cases (37%) and low CD8 score was found in 24(63%) cases. p53 mutant colorectal cancer expressing low CD8 score were signicantly correlated with increased nodal metastasis (p value<0.027) and age ((p value<0.03). This study highlights the signicant correlation of CD8 T-lymphocyte with Age and Nodal metastasis, thus helping to predict the prognosis of colorectal cancers and reduce social stigma caused by this disease
EFFECT OF NALBUPHINE AND TRAMADOL IN POST-SPINAL ANAESTHESIA SHIVERING: A COMPARATIVE STUDY
Authors: Kour Manmeet , Gurtoo Hitesha , Kumar Ashwani
Published: May 2023

Background: In Spinal anaesthesia, a consequence of impaired thermoregulatory control, shivering is one of the most frequently reported complications of central neuraxial blockade, affecting 40–70% of patients. Nalbuphine is a mixed opioid agonist–antagonist with high afnity for the opioid receptor that functions as both a competitive opioid antagonist and a partial opioid agonist. Theoretically, nalbuphine could have signicant anti-shivering effects on post-anaesthetic shivering. This prospecti Methods: ve randomised (computer-generated) double-blinded study was conducted at Department of Anaesthesiology and Intensive Care, Government Medical College Jammu J&K, after obtaining approval from hospital ethical committee. Randomisation was done using a computer-generated number where patients were randomly allocated into two groups: Group-N and Group-T. We conned our investigation to 84 patients divided into two equal groups of 42 people. The non- Results: signicant difference was observed in age, gender, BMI, ASA physical status, duration of surgery, and duration of spinal anesthesia between the groups. The drug was found to signicantly reduce SBP, increase DBP, and increase MAP in the group given the drug compared to the nalbuphine group. The time taken to control shivering was signicantly shorter in the group-T. The group-T also had a lower Ramsay Sedation Scale score, indicating less sedation compared to the group-N group. The drug did not cause any adverse effects, while sedation, hypotension, and bradycardia were observed in the group-N. Nausea, vomiting, and dizziness were reported in the group-T, but not in the group-N. There was no signicant difference in the effectiveness of shivering control between the two groups. Both i Conclusion: ntravenous nalbuphine 0.05 mg/kg and tramadol 1 mg/kg are effective in managing post-spinal anesthesia shivering. However, tramadol had a shorter time to control shivering than nalbuphine. Both drugs had minimal effects on blood pressure and heart rate, and the side effects observed were minor and treatable
A COMPARATIVE STUDY OF CLONIDINE AS ADJUVANT TO ROPIVACAINE AND ROPIVACAINE ALONE IN EPIDURAL ANESTHESIA FOR LOWER LIMB SURGERIES
Authors: Singh Mandeep , Kumar Mukesh , Kaur Sarvjeet , Kumar Vijay , Singh Bikramjeet
Published: May 2023

Introduction:Epidural anaesthesia is one of the most common regional anaesthetic techniques used for lower abdominal and lower limb surgeries. Due to similar analgesic properties, lesser motor blockade and decreased cardiotoxic tendency ropivacaine is increasingly used instead of bupivacaine now a days. Clonidine has been frequently used as an adjunct to local anesthetics because it improves the quality of anesthesia, reduces the dose requirement of the anesthetic agent and provides a more stable cardiovascular course. Aims And Objectives: 1. To evaluate effect of ropivacaine alone in epidural anaesthesia for lower limb surgeries. 2. To evaluate effect of clonidine as adjuvant to ropivacaine in epidural anaesthesia for lower limb surgeries. 3. To compare effect of ropivacaine alone and clonidine as adjuvant to ropivacaine in epidural anaesthesia for lower limb surgeries. Material And Method: The study was conducted in the department of Anaesthesiology, GGS Medical College, Faridkot, after approval by Hospital Ethical Committee. Written informed consent was obtained from each patient. The total of 90 patients were allocated into 2 groups of 45 patients each:1.Group R (n=45) - 19 ml of 0.75% ropivacaine + 1 ml of normal saline (20 ml) 2.Group RC (n=45)-19 ml of 0.75% ropivacaine + 75μg of clonidine diluted to 1 ml (20 ml). The onset time for sensory and motor block, the maximum level of sensory block , duration of analgesia and side effects were recorded. The demographic prole were comparable in terms Results: of age, sex, weight which was statistically nonsignicant in both the groups. Clonidine group (RC) had rapid onset of sensory and motor blockade (p=0.001) and prolonged duration analgesia (p=0.001). There was no statistically signicant difference in HR, SBP, DBP, MAP monitored at various intervals between the two groups. Conclusion: The use of Clonidine as an adjuvant to Ropivacaine for epidural anaesthesia produces early onset of sensory and motor blockage and prolonged the duration of analgesia as compared to ropivacaine alone, with minimal changes in haemodynamic parameters and adverse effects.
DEPRESSION AND ANXIETY DISORDERS IN PATIENTS OF CHRONIC KIDNEY DISEASE UNDERGOING HAEMODIALYSIS
Authors: GV Jithendra , P Sreelatha.
Published: May 2023

Introduction: Chronic renal disease (CKD) is a devastating and life-threatening illness. Haemodialysis is one of the renal replacement treatments for CKD patients. chronic renal illness has signicant impact on the social and psychological states of patients making them vulnerable to psychiatric disorders. Therefore, the purpose of this study was to assess the frequency of depression and anxiety in these patients. Materials and Methods:The present study was a cross-sectional study on 71 CKD patients undergoing haemodialysis. Patients were selected using the purposive sampling method. The data gathering tools in this study included demographic information form, MINI and the Hamilton depression and anxiety rating scales. The data were analysed using descriptive statistics (percentage, mean, and standard deviation) as well as Chi-square test in SPSS version 20. Results: In 71 patients, 70.4% of patients had depression and 63.2% had anxiety using HADS and HARS rating measures. Most of these cases had mild depression and mild anxiety scores. There was no signicant association found between the depression and anxiety scores and age, gender, marital status, and income and other demographic and clinical factors. Conclusion: People with CKD undergoing haemodialysis had signicantly high depression and anxiety scores
COMPARATIVE ANALYSIS OF MRI AND ARTHROSCOPIC FINDINGS FOR KNEE ACLAND MENISCAL INJURIES
Authors: Tolani Avinash
Published: May 2023

Background and Aim: Common knee injuries include meniscal or ligamentous tears, which can cause discomfort, instability, and movement restrictions. The knee is evaluated using a variety of imaging techniques, such as radiography, CT scans for fractures, and MRIs for soft tissue damage to the knee joint. Our study's objective was to compare the results of the aforementioned two methods and assess the radiological and arthroscopic ndings of anterior cruciate and meniscal injuries. Find out which of the two is more effective at accurately diagnosing ACL and meniscal injury. Material and Methods: This is a prospective study that was done on at least 200 patients who met the inclusion criteria and were being treated for knee injuries at a Tertiary Care Teaching Hospital in India. Among of them, 200 knee injury patients had an MRI, clinical examination, and arthroscopy. Many statistical tests were used to compare and assess the outcomes. These arthroscopy and MRI data were used to compute the accuracy, sensitivity, and specicity. Results: In our investigation, the sensitivity, positive predictive value, and accuracy of an MRI scan in identifying ACL injury were 91.10%, 93.10%, and 87.5%, respectively. In our investigation, the sensitivity, positive predictive value, and accuracy of MRI scan in diagnosing medial meniscus damage were, respectively, 86.8%, 90.12%, and 87.2%. In our study, lateral meniscus injury was detected by MRI scan with 74.15% sensitivity, 71.25% PPV, and 84% accuracy, respectively. Conclusion: Our research demonstrated good sensitivity, specicity, and accuracy for knee joint ACLand meniscal injuries. Meniscus and ACLdamage can be accurately diagnosed by MRI. For therapeutic arthroscopy, MRI is a suitable screening tool, negating the need for diagnostic arthroscopy in the majority of patients. For the assessment of ligamentous and meniscus injuries, magnetic resonance imaging is a reliable and noninvasive method.
STUDY OF HEMATOLOGICAL INDICES IN HEART FAILURE WITH REDUCED EJECTION FRACTION AND THEIR ASSOCIATION WITH IN-HOSPITAL OUTCOME.
Authors: Bhagvath K Bhavana , S T Kavya
Published: May 2023

Background And Objectives: In heart failure with reduced ejection fraction, various hematological parameters are known to be of prognostic signicance. This study aimed to correlate these parameters with in-hospital outcome in patients. Patients hospitalized heart failure Methods: were enrolled. Hematological indices, including white blood cell counts, neutrophil counts, neutrophil-to-lymphocyte ratio, platelet-tolymphocyte ratio and monocyte to lymphocyte ratio were recorded. The study considered 55 Results: patients out of which 29 were male and 26 were female.mean duration of stay in hospital was 5.29 + 3.12. ). Patients with NLR > 3.74 & with MLR > 0.49 had a 8.41 & 3.33 times higher risk of in-hospital mortality Interpretation And Conclusion: In this study ,NLR, MLR and PLR were independent predictors of in hospital mortality with NLR > 3.74 having the highest independent predictor power in prediction of in-hospital mortality
ROLE OF SEROUS FLUID CYTOLOGY IN BOTH NON-MALIGNANT AND MALIGNANT LESIONS WITH EMPHASIS ON CYTOMORPHOLOGY OF RARE METASTATIC MALIGNANCIES TO SEROUS CAVITY
Authors: More Nilam , Mohd Ilyas Abeer , Sisodiya Sneha , Sawant Kavita , P Naik Leena
Published: May 2023

Context: Serous effusion cytology is an important investigation for diagnosis of neoplastic and non-neoplastic diseases. Malignant cells in serous uid cytology indicates advanced stage. To evaluate the utility of serous ui Aims: d cytology in differential diagnosis of malignant and nonmalignant serous effusions and to emphasize the cytomorphology of rare metastatic malignancies. The importance of cell block with immunocytochemistry for diagnostically challenging cases was also highlighted. T Settings and Design: his was a one year retrospective study in which cases were classied into malignant and non-malignant. Immunohistochemistry was performed on cell blocks of difcult to diagnose cases. Methods and Material: Total 356 serous uids (pleural, peritoneal and pericardial uids) were centrifuged, cytocentrifuged and stained with Papanicolaou and Giemsa. Clinical history, radiological ndings and other relevant parameters were noted. 184 cases were of pleural Results: uid, 168 of peritoneal uid and four were of pericardial uid. Lung malignancies and ovarian malignancies were the most common primary sites in pleural and peritoneal uids respectively. Out of 40 positive for malignancy cases, 22 were rst conrmed on cytology. Clinical diagnosis of Boerhaave's syndrome was conrmed on cytology. Rare presentations of metastasis of squamous cell carcinoma, pleomorphic lobular carcinoma and clear cell type renal cell carcinoma were diagnosed on cytology. Rare m Conclusions: etastatic malignancies to serous cavity pose diagnostic challenges on cytology. Both, cytopathologists and clinicians should be aware of these rare malignancies. A vigilant cytopathologist can identify malignant cells based on cytomorphological features and give accurate diagnosis with the help of ancillary tests and lead clinicians for further work up, evaluation and treatment of the patients
COMPARATIVE ASSESSMENT OF REMINERALISATION OF TOOTH ENAMEL, DEMINERALISED BY ACIDIC SOFT DRINK USING 2 COMMERCIALLY AVAILABLE NON-FLORIDATED REMINERALISING TOOTH PASTES – INVITRO STUDY
Authors: Antonio De Menezes Nigel , R Patil Chetan , Pujar Madhu
Published: May 2023

A number of various formulations of dentifrices exist in the market. There is a big concern of uoride ingestion with the toothpaste containing highuoride content in children. Carbonated Soft drinks, have been suggested as causing damage to the teeth bring about demineralization leading to dental caries. Therefore, the present study has been undertaken to assess and compare the remineralization potential of two non uoridated dentifrices with different compositions on tooth enamel in vitro by using surface prolometer
A COMPARATIVE EVALUATION OF CONTINUOUS AND INTERMITTENT NASOGASTRIC FEEDING IN LBW NEONATES.
Authors: Monika Monika , Punj Ajay , Nauriyal Deepty , Kartik Kartik
Published: May 2023

Background: To compare outcome between continuous and intermittent nasogastric feeding in low birth neonates. Objective: The aim of this study was to compare outcome between continuous and intermittent nasogastric feeding in low birth neonates. Methods: 80 Patients were randomally divided in two groups i.e group A and group B. The neonates in the Group A received continuous nasogastric feed via continuous infusion pump while in Group B neonates received intermittent nasogastric feed in the form of boluses every 2-3 hour over 15-20 minute duration. Each neonate was followed for 15 days, Then data was collected and analysed. If there were no other clinical signs, feeding was stopped for three hours . After 15 days outcomes were recorded and analaysed that which feed had better results. Result: Mortality was reported more in group B as compared to group A. Morbidity was reported more in group B as compared to group A. Regaining of birth weight (in days) was found earlier in group A as compared to Group B. Conclusion : While comparing continuous feeding with intermittent feeding in low birth weight neonates we reached on conclusion that continuous feeding is better then intermittent feeding in terms of various outcomes.
STUDY TO ASSESS IMPACT OF PICTORIAL/ TEXT WARNINGS ON CIGARETTE, BEEDI AND CHUTTA PACKETS ON SMOKING HABITS.
Authors: Sri Himabindu Vaddi , Kannan Natarajan , Kumar Manne Rakesh , Sarath Prathi Venkata , Swapna Sridevi Beeraka , Vemareddy Sravya
Published: May 2023

Introduction: Health warnings and pictures on cigarettes and other forms of smoking tobacco packets is intended to inform customers of potential dangers associated with using the product. This study was done to evaluate effectiveness and impact of health warnings and pictures printed on cigarette, beedi & chutta packets on smokers. The study population consisted of Method: 100 smokers who visited our college for oral and dental problems. During oral examinations, they were questioned about their smoking habits and various aspects regarding text and pictures printed on the cigarette, beedi and chutta packets with the help of a specically designed and validated questionnaire and sociodemographic data was collected from them. This study showed higher percentage of literacy among urban smokers(94.7%) compared Results: to rural smokers(72.1%). Absence of printed warnings in local Telugu language was tagged by many of the literate smokers as impeding their ability to read and understand the warnings. Most of the smokers saw pictures on the packets but chose to ignore them as they thought these as unlikely to affect them. Few of them attempted to quit the tobacco habit previously but failed on account of addictive nature of the habit, stress and tension. The health Conclusion: warnings and pictures printed on packets of tobacco products were marginally effective in inducing smokers to quit habit and there is need for more awareness in rural areas and need for printing of health warnings in regional languages.