bluuebunny/crossref_metadata_2025 huggingface dataset:
Antibacterial activity against Staphylococcus aureus of chitosan/chondroitin sulfate nanocomplex aerogels alone and enriched with erythromycin and elephant garlic (Allium ampeloprasum L. var. ampeloprasum) extract
Authors: Gómez María Angélica , Bonilla Jennifer Marcela , Coronel María Alejandra , Martínez Jonathan , Morán-Trujillo Luis , Orellana Sandra L. , Vidal Alejandra , Giacaman Annesi , Morales Carlos , Torres-Gallegos César , Concha Miguel , Oyarzun-Ampuero Felipe , Godoy Patricio , Lisoni Judit G. , Henríquez-Báez Carla , Bustos Carlos , Moreno-Villoslada Ignacio
Published: January 2018

The antibacterial activity against Staphylococcus aureus of aerogels fabricated from colloidal suspensions of chitosan/chondroitin sulfate nanocomplexes is analyzed. Upon freeze-drying the colloidal suspensions, the aerogels presented a porous structure made of microsheets and microfibers. The aerogels could, in addition, be loaded with antimicrobial agents. Loaded with the antibiotic erythromycin, the aerogels showed crystalline deposits, affecting the topography of the samples as well as their mechanical properties, showing a decrease on the apparent Young’s modulus and hardness at 40% deformation. Loaded with elephant garlic (Allium ampeloprasum L. var. ampeloprasum) extract, the aerogels showed texturization of the microsheets and microfibers, and the higher relative mass allowed an increase on the apparent Young’s modulus and hardness at 40% deformation with respect to pristine aerogels. Unloaded aerogels showed activity against Staphylococcus aureus, including a methicillin-resistant strain. The release of erythromycin from the aerogels to an agar environment is governed by equilibrium forces with the polysaccharides, which allow modulating the load of antibiotic and its concomitant diffusion from the material. The diffusion of the active components of the elephant garlic extract did not show a dependence on the polysaccharide content, revealing a week interaction. The elephant garlic extract resulted active against the methicillin-resistant Staphylococcus aureus strain, while resistance was found for the antibiotic, revealing the therapeutic potential of the natural extract. The antimicrobial aerogels may be used for several therapeutic purposes, such as healing of infected chronic wounds.
Tailored silica nanospheres: an efficient adsorbent for environmental chromium remediation
Authors: Ali Zarshad , Ahmad Rashid , Khan Aslam
Published: January 2018

This manuscript reports the synthesis and characterization of caprylpyrazolone tailored silica nanospheres, synthesized through sol–gel procedure by activating the silica nanospheres with organosilane precursor and grafting with caprylpyrazolone. Its successful attachment to the silica is confirmed by FTIR, TGA and elemental techniques. The feasibility of the synthesized nanospheres as adsorbent was systematically checked by elimination of trace level of Cr(III) from aqueous medium, using radiotracer technique. A number of factors such as effect of pH, agitation time, adsorbent and adsorbate dosage were optimized to guarantee the use of the adsorbent for practical use. Various counter ions were added to the matrix solution to check the selectivity of the synthesized sorbent. Various rate equations and adsorption isotherms such as Freundlich, D-R and Langmuir were employed to suggest the mechanistic pathway of the adsorption process. The Cr(III) extraction was monitored at room and elevated temperatures and thermodynamic parameters such as change in enthalpy, entropy, and Gibbs free energy of the metal ion uptake were computed. The removal of Cr(III) is endothermic (∆H=30.00 J mol−1 K−1) and spontaneous (∆S=105.43 J mol−1 K−1) in nature. Application of the adsorbent to real water samples demonstrated the practical utility of the adsorbent. The sorbent displayed good stability. Its cleaning efficiency is not significantly affected after various adsorption-desorption cycles and so it can be used repeatedly.
Ovariectomy-induced bone loss in TNFα and IL6 gene knockout mice is regulated by different mechanisms
Authors: Zhu Siyi , He Hongchen , Gao Chengfei , Luo Guojing , Xie Ying , Wang Haiming , Tian Li , Chen Xiang , Yu Xijie , He Chengqi
Published: January 2018

We examined the effects of tumor necrosis factor-α (TNFα) and interleukin-6 (IL6) gene knockout in preserving the bone loss induced by ovariectomy (OVX) and the mechanisms involved in bone metabolism. Twenty female wild-type (WT),TNFα-knockout (TNFα−/−) orIL6-knockout (IL6−/−) mice aged 12 weeks were sham-operated (SHAM) or subjected to OVX and killed after 4 weeks. Bone mass and skeletal microarchitecture were determined using micro-CT. Bone marrow stromal cells (BMSCs) from all three groups (WT, TNFα−/−and IL6−/−) were induced to differentiate into osteoblasts or osteoclasts and treated with 17-β-estradiol. Bone metabolism was assessed by histological analysis, serum analyses and qRT-PCR. OVX successfully induced a high turnover in all mice, but a repair effect was observed in TNFα−/−and IL6−/−mice. The ratio of femoral trabecular bone volume to tissue volume, trabecular number and trabecular thickness were significantly decreased in WT mice subjected to OVX, but increased in TNFα−/−mice (1.62, 1.34, 0.27-fold respectively;P < 0.01) and IL6−/−mice (1.34, 0.80, 0.22-fold respectively;P < 0.01). Furthermore, we observed a 29.6% increase in the trabecular number in TNFα−/−mice when compared to the IL6−/−mice. Both, TNFα−/−and IL6−/−BMSCs exhibited decreased numbers of TRAP-positive cells and an increase in ALP-positive cells, with or without E2 treatment (P < 0.05). While the knockout ofTNFαorIL6significantly upregulated mRNA expressions of osteoblast-related genes (Runx2andCol1a1) and downregulated osteoclast-related mRNA forTRAP,MMP9andCTSK in vivoandin vitro,TNFαknockout appeared to have roles beyondIL6knockout in upregulatingCol1a1mRNA expression and downregulating mRNA expressions of WNT-related genes (DKK1andSost) and TNF-related activation-induced genes (TRAF6). TNFα seemed to be more potentially invasive in inhibiting bone formation and enhancing TRAF6-mediated osteoclastogenesis than IL6, implying that the regulatory mechanisms of TNFα and IL6 in bone metabolism may be different.
Maintenance of Genome Integrity by Mi2 Homologs CHD-3 and LET-418 in Caenorhabditis elegans
Authors: Turcotte Carolyn A , Sloat Solomon A , Rigothi Julia A , Rosenkranse Erika , Northrup Alexandra L , Andrews Nicolas P , Checchi Paula M
Published: January 2018

Meiotic recombination depends upon the tightly coordinated regulation of chromosome dynamics and is essential for the production of haploid gametes. Central to this process is the formation and repair of meiotic double-stranded breaks (DSBs), which must take place within the constraints of a specialized chromatin architecture. Here, we demonstrate a role for the nucleosome remodeling and deacetylase (NuRD) complex in orchestrating meiotic chromosome dynamics in Caenorhabditis elegans. Our data reveal that the conserved Mi2 homologs Chromodomain helicase DNA-binding protein (CHD-3) and its paralog LET-418 facilitate meiotic progression by ensuring faithful repair of DSBs through homologous recombination. We discovered that loss of either CHD-3 or LET-418 results in elevated p53-dependent germ line apoptosis, which relies on the activation of the conserved checkpoint kinase CHK-1. Consistent with these findings, chd-3 and let-418 mutants produce a reduced number of offspring, indicating a role for Mi2 in forming viable gametes. When Mi2 function is compromised, persisting recombination intermediates are detected in late pachytene nuclei, indicating a failure in the timely repair of DSBs. Intriguingly, our data indicate that in Mi2 mutant germ lines, a subset of DSBs are repaired by nonhomologous end joining, which manifests as chromosomal fusions. We find that meiotic defects are exacerbated in Mi2 mutants lacking CKU-80, as evidenced by increased recombination intermediates, corpses, and defects in chromosomal integrity. Taken together, our findings support a model wherein the C. elegans Mi2 complex maintains genomic integrity through reinforcement of a chromatin landscape suitable for homology-driven repair mechanisms.
A Case of Cardiomyopathy Due to Premature Ductus Arteriosus Closure: The Flip Side of Paracetamol
Authors: Schierz Ingrid Anne Mandy , Giuffrè Mario , Piro Ettore , La Placa Simona , Corsello Giovanni
Published: January 2018

Paracetamol (acetaminophen or N-acetyl-p-aminophenol) is considered a safe analgesic and antipyretic nonsteroidal antiinflammatory drug commonly used during pediatric ages and during pregnancy. We report on a term neonate with closed ductus arteriosus, severe cardiomyopathy, right ventricular dysfunction, and functional stenosis of pulmonary arteries at birth after maternal self-medication with paracetamol and consumption of polyphenol-rich foods in late pregnancy. This drug, especially when associated with other vasoconstrictors (such as polyphenols), interferes with prostaglandin metabolism, which seriously accentuates the intrauterine ductus arteriosus constriction and leads to pharmacologic adverse events. We suggest maternal educational programs to avoid risky self-medications and provide training for the best diets.
CARACTERIZACIÓN MAGNÉTICA E HIPERFINA DE LA TRANSFORMACIÓN TÉRMICA CuO - Fe2O3 A Fe3O4
Authors: Betancur Juan D. , Restrepo Johans , Fernandez Jhon J. , Perez Oswaldo
Published: January 2018

Se presenta un estudio magnético acerca de la transformación térmica de hematita dopada con CuO (Fe2O3 + CuO). El tratamiento térmico se realizó a una temperatura de 375 ± 1 ºC, en una atmosfera controlada compuesta por 20% de hidrogeno y 80% de nitrógeno. Las muestras fueron caracterizadas por espectroscopía Mössbauer a temperatura ambiente, magnetización en función de la temperatura y ciclos de histéresis a 10K. Los resultados sugieren que los campos hiperfinos y los anchos de línea A y B permanecen esencialmente constantes con el aumento de la concentración de CuO, mientras que a la vez surge una componente paramagnética, lo cual es indicativo de la aparición de un precipitado o nueva fase de Fe-Cu, i.e. no hay una incorporación efectiva del cobre en la estructura de la magnetita. La magnetización de saturación cae aproximadamente de 87 emu/g a 78 emu/g, consistente con la presencia de dicha fase paramagnética. Se presenta también un aumento de la coerctividad desde ~576 Oe hasta ~621 Oe con el aumento del %CuO desde 2% hasta 20 %. Tal aumento se atribuye también a dicha fase paramagnética actuando como centro de anclaje de las paredes de dominio, sumado al efecto de anclaje de las posibles vacancias inducidas por el tratamiento térmico. Finalmente, se observa una inversión de la magnetización en la temperatura de Verwey. Los datos sugieren que mediante el método de síntesis empleado se obtienen partículas de magnetita Fe3O4 coexistiendo con precipitados de Fe-Cu, lo cual modifica las propiedades magnéticas y genera un efecto interesante en la magnetización a la temperatura de Verwey.
Escala de Autorrelato de Trapaça-Admissão: Evidências de Validade Fatorial e Precisão
Authors: Gouveia Valdiney Veloso , Moura Hysla Magalhães de , Santos Layrtthon Carlos de Oliveira , Nascimento Anderson Mesquita do , Guedes Italo De Oliveira , Gouveia Rildésia Silva Veloso
Published: January 2018

El estudio tuvo como fin adaptar al contexto brasileño la Escala de Autoinforme de Trampa- Admisión(EAT-A), reuniendo evidencias de su validez factorial y consistencia interna. Participaron 441 estudiantes (m=16 años, 54.6% del sexo femenino), divididos al azar en dos grupos. Todos respondieron a EAT-A y a preguntas demográficas. El análisis de componentes principales evidenció una estructura bifactorial, cuyos factores presentaron alfas de Cronbach (α) supe-riores a .80 (G1). Esta estructura fue corroborada por medio de análisis factorial confirmatorio (por ejemplo, CFI=.87 y RMSEA=.08). Se concluyó que esta escala se mostró psicométricamente adecuada y reunió evidencias de validez factorial y consistencia interna, y puede utilizarse para mensurar plagio en contexto académico.
Detección de anticuerpos para Trypanosoma cruzi en donantes de sangre. Caquetá, Colombia, 1995 a 2010
Authors: Beltrán Durán Mauricio , Hilarión Gaitán Liliana Beatriz , Bermudez María Isabel , Berrio Pérez Maritza
Published: January 2018

Objetivo Caracterizar epidemiológicamente los casos reactivos y confirmados para Trypanosoma cruzi en donantes de sangre del departamento de Caquetá desde 1995 a 2010.Materiales y Métodos Estudio descriptivo, retrospectivo. La información fue obtenida en el banco de sangre y Laboratorio Departamental de Salud Pública de Caquetá, los datos se colectaron en un formulario estandarizado diseñado en Microsoft Excel® convariables específicas, posteriormente se depuró, corroboró y completó la información con las bases de datos nacionales Registraduría Nacional de Colombia y Base de Datos Única de Afiliados del Fondo de Solidaridad y Garantía (FOSYGA) del sistemade salud colombiano. En el análisis se utilizó estadística descriptiva uni y bivariada en Microsoft Excel® y un análisis de correspondencia múltiple (ACM) con el programador matemático R® versión 3.0.Resultados De 42 516 donaciones tamizadas, se detectaron 261 casos reactivos, 92 resultaron positivos para T. cruzi, 12 negativos y 157 casos sin dato de confirmación. Se consultó la posible ubicación caso a caso con las bases de datos nacionales, estableciendofactibles migraciones a diferentes zonas del país.Conclusión La caracterización y ubicación actual por medio del contraste y búsqueda de información con bases de datos nacionales de los casos positivos confirmados para T. cruzi es un avance importante en salud pública, pues es la primeria línea de información existente en Colombia que entrega gran cantidad de datos caso a caso, con el fin que las autoridades competentes inicien búsqueda activa para el manejo clínico pertinente.
Calidad de vida relacionada con salud en la población Colombiana: ¿cómo valoran los colombianos su estado de salud?
Authors: Rojas Reyes María Ximena , Gomez-Restrepo Carlos , Rodríguez Viviana A. , Dennis-Verano Rodolfo , Kind Paul
Published: January 2018

Objetivo Determinar la percepción sobre la calidad de vida relacionada con salud (CVrS) que tiene la población adulta en Colombia.Métodos encuesta poblacional en una muestra representativa de la población rural y urbana, de 18 y más años. Se midió la CVrS con el instrumento EQ5D-3L y la escala visual análoga, como parte de la cuarta Encuesta Nacional de Salud Mental. Las estimacionesfueron ajustadas por el diseño de muestreo y se acompañan de intervalos de confianza al 95 %.Resultados 1 0867 personas completaron la medición; 69,7 % (IC95 % 66,9 a 68,9) de la población reporto estar en “salud completa”; la mayor proporción de personas valoraronsu salud por encima de 80 puntos. La presencia de “moderado dolor o malestar”, seguida de estar “moderadamente angustiado o deprimido” fueron las alteraciones más frecuentes. Los adultos jóvenes tienden a valorar mejor su salud que los adultosmayores. No hay diferencias en la percepción de la salud entre regiones del país.Conclusiones La calidad de vida relacionada con salud en la población colombiana  es mayor de 80 puntos en una escala de 1 a 100. Las alteraciones como angustia y depresión y la percepción del dolor, fueron las más comúnmente reportadas por los colombianos. La situación de pobreza y el bajo nivel educacional son determinantes de la valoración que hacen los colombianos de su CVrS.
Estágio em Serviço Social: reflexões a partir da realidade da supervisão de campo / Training in Social Work: reflections from the reality of stage supervision
Authors: Xavier Freitas Emanuel Jones , Faria Luciane Cássia
Published: January 2018

O presente trabalho tem por objetivo problematizar as características do estágio supervisionado em Serviço Social, especialmente sob o prisma da supervisão direta de estágio em campo, abordagem ainda incipiente sob o ponto de vista de referências literárias, embora se constitua como dimensão formativa relevante e que demanda intensa e profunda reflexão. Desenvolveu-se estudo de nível descritivo (HERNANDEZ et al., 2013) e de natureza qualitativa (GOGOY, 1995), instrumentalizado por formulário survey (PINSONNEAULT; KRAEMER, 1993), por meio do qual buscou-se observar características dos assistentes sociais no processo de supervisão direta de estágio em campo. Conclui-se, pelo presente estudo, que qualificar o processo de supervisão de campo de estágio segue como relevante desafio a ser superado pela categoria profissional, dadas as condições por meio das quais o processo tem sido conduzido no cenário contemporâneo.
¿El Fin del Superciclo del Cobre y de las Reformas Sociales en Chile? / The end of the copper super cycle and the social reforms in Chile?
Authors: Flores Consuelo Silva , Cortés Claudio Lara
Published: January 2018

Chile es un país mundialmente conocido por su elevada producción de cobre. También reviste especial importancia el aporte de ingresos que realiza al Estado provenientes de las exportaciones.A partir del año 2003, se inicia el “super ciclo del cobre” como resultado del significativo aumento del precio a nivel internacional. Esta tendencia impactó positivamente en diversos sectores de la sociedad: académicos, empresarios y gobernantes; al punto de impulsar nuevos proyectos y millonarias inversiones. En este periodo, los mayores traspasos al fisco permitieron no solo ahorrar parte de los ingresos fiscales, sino que también financiar gastos estatales y varias reformas sociales comprometidas por los gobiernos de la época.A partir de 2013, se inicia una caída de los precios, incluso dramáticamente en los años siguientes, arrastrando a la industria a una compleja crisis. En los últimos quince años la productividad ha caído permanentemente y la producción se ha visto estancada, cuyo trasfondo son la reducción sostenida de las leyes del mineral y el alza de los costos de producción. Esta severa crisis “económica” que enfrenta el ciclo de explotación capitalista del cobre está en contradicción con la degradación indiscriminada e irreversible del ciclo de vida del metal y los recursos naturales. Esta situación, más el fracaso de la reforma tributaria, ha tenido serias repercusiones para las cuentas fiscales.
EVALUATION OF CORROSION AND TRIBOLOGICAL BEHAVIOR OF ELECTRODEPOSITED TUNGSTEN ALLOYS
Authors: Vernickaite E. , Cesiulis H. , Tsyntsaru N.
Published: January 2018

Tungsten alloy coatings with iron group metals (Ni, Fe, Co) are considered as advanced materials for various surface engineering applications. Such coatings should be resistant to mechanical and corrosive damage, and to have improved functionality and durability. Accordingly, the objectives of this review consist in a comparative study of available literature on corrosive and wear behavior of electrodeposited tungsten alloys with iron group metals, including our recent results on evaluation of electrodeposited Co-W coatings. The wear and corrosion resistance of Ni-W, Fe-W and Co-W strongly depends on the chosen deposition conditions and subsequently on tungsten content and structure of obtained protective coatings.
EXPERIENCES WITH WEB 2.0 IN SCHOOL SETTINGS: A FRAMEWORK TO FOSTER EDUCATIONAL PRACTICES BASED ON A PERSONAL LEARNING ENVIRONMENT PERSPECTIVE
Authors: Bassani Patrícia B. Scherer , Barbosa Débora Nice Ferrari
Published: January 2018

Abstract: Studies involving the use of digital technologies in educational settings, based on the concept of Personal Learning Environments (PLE), show the possibilities of enhancing educational processes through a pedagogical approach, which benefits from the affordances of technologies. We understand that a PLE is organized with tools, mechanisms, and activities that each student uses to read, produce and share. These actions are possible through different web 2.0 applications. This study aims to foster educational practices with technologies in the context of the classroom from the perspective of the PLE. The research, based on a qualitative approach, is organized into two phases. First, we propose a framework to assist teachers in the selection of web tools to foster educational practices based on PLE. Second, we present and analyze the results of a qualitative study, which involves the use of the proposed framework in educational practices conducted in the final years of elementary education in a private school in Brazil. Results point out that the proposed framework can be used to support the teachers in designing educational practices involving the use of digital technologies to promote the student’s PLE.
DESENVOLVIMENTO PROFISSIONAL DOCENTE: A TRAJETÓRIA DE UMA PROFESSORA SUPERVISORA NO PIBID
Authors: Nascimento Wilson Elmer , Barolli Elisabeth
Published: January 2018

RESUMO: Neste trabalho apresentamos a análise da trajetória de uma professora enquanto supervisora do Programa Institucional de Bolsas de Iniciação à Docência (PIBID). Por meio de uma análise narrativa, reconstruímos a história da professora no projeto, explicitando os principais aspectos de desenvolvimento profissional. Para tanto, nos apoiamos nas teorizações de Bernard Lahire sobre o conceito de disposições e sua articulação com as condições contextuais. Na análise da trajetória da professora inferimos disposições (participativa, reflexiva e à atualização) que foram mobilizadas ou atualizadas em determinadas características contextuais proporcionadas pelo PIBID. A mobilização dessas disposições, atravessadas por um contexto favorável, nos indicou aspectos de desenvolvimento profissional, como satisfação pessoal, reflexão sobre a própria prática, atualização teórica, entre outros. Os resultados evidenciam que é na confluência das condições contextuais com as maneiras pelas quais os sujeitos vivenciam essas condições, por meio de suas disposições, que o desenvolvimento profissional pode se dar de maneira efetiva.
CAMINHOS DE APRENDIZ DE PROFESSORA: PROCESSOS IDENTITÁRIOS EM UMA COMUNIDADE DE APRENDIZAGEM ONLINE
Authors: Martins Rosana Maria , Anunciato Rosa Maria Moraes
Published: January 2018

Resumo: Este artigo discorre sobre a constituição, em contextos colaborativos, da identidade docente de futuras professoras participantes de uma investigação sobre uma comunidade de aprendizagem online. Para este texto, buscou-se compreender como se expressam, nas narrativas, os indícios de constituição da identidade docente de licenciandas em formação. Os dados dessas narrativas autobiográficas mostraram como esse processo contribui para a constituição da identidade profissional docente e do desenvolvimento profissional, que se revelam em constante tensão, em um continuum, em que as experiências vivenciadas transcendem a polaridade teoria-prática e estão sempre vinculadas ao saber que emerge no próprio viver e fazer, a fim de significá-lo, problematizá-lo ou iluminá-lo.
Confluência do Capital Social, Empoderamento e Governança Ambiental na Sadia Qualidade de Vida em Comunidades Rurais no Ceará
Authors: Sousa Magda Cristina de , Lima Patrícia Verônica P. S. , Khan Ahmad Saeed , Rocha Leonardo Andrade
Published: January 2018

Resumo: A compreensão da forma como capital social, empoderamento e governança ambiental se relacionam em escala local pode fortalecer o papel do poder público e de instituições privadas na implementação de estratégias de promoção da qualidade de vida. Nessa perspectiva, o objetivo deste estudo é analisar a confluência do capital social, empoderamento e governança ambiental para a sadia qualidade de vida, em comunidades rurais, no Ceará. Para tanto, foram utilizados dados primários obtidos junto a representantes das comunidades. A operacionalização dos conceitos analisados foi realizada por meio da construção de índices agregados. Como principal método de análise foi estimado um modelo de equações estruturais. Os resultados mais relevantes mostraram que o capital social e o empoderamento se relacionam entre si na promoção da sadia qualidade de vida nas comunidades estudadas, enquanto a governança ambiental não consegue promover mudanças nesse sentido. Ficou evidente a importância da participação da comunidade no desenvolvimento/envolvimento melhorando, assim, o acesso a direitos sociais com a participação responsável e solidária para alcançar a sadia qualidade de vida, em um meio ambiente com equilíbrio ecológico, às presentes e futuras gerações.
Scientific production of researchers in the Nutrition field with productivity fellowships from the National Council for Scientific and Technological Development
Authors: PINHO Lucinéia de , MARTELLI-JÚNIOR Hercílio , OLIVEIRA Eduardo Araujo , MARTELLI Daniella Reis Barbosa
Published: January 2018

ABSTRACT Objective To characterize researchers in the Nutrition field awarded with Conselho Nacional de Desenvolvimento Científico e Tecnológico research productivity fellowships and evaluate their scientific production according to an analysis of curricula registered on the Lattes Platform. Methods The study is cross-sectional and descriptive in scope, and was developed from October 2014 to February 2015. The productivity fellowships/Conselho Nacional de Desenvolvimento Científico e Tecnológico researchers were identified from the Lattes Platform, and their curriculum lattes were downloaded for data collation. Information on the profiles of the researchers and the bibliometric data of productivity (published articles, articles and citations registered on ISI/Web of Science and Scopus databases, impact of the publications, and academic advising) were collected. Results Eighty researchers were identified and evaluated. A total of 67.5% were female and 53.5% were classified as category 2. Approximately two-thirds (65.0%) were located in Southeastern Brazil. The sum of articles published by the researchers from the beginning of their career until the end of the study came to 7,358 (median=84 per researcher, interquartile range=53–285). Of these publications, 45.0% were indexed in the Web of Science and 62.0% in Scopus. Of the journals where the articles were published, 70.0% had an impact factor. Conclusion Most publications were performed in journals with an impact factor, indicating the influence of Brazilian nutrition studies on society and their potential for guiding public policies on nutrition and health.
Desvendando o Endereço Físico do Telescópio James Webb
Authors: Fortes Elaine Cristina Ferreira Silva , Azevedo Franciane , Kolland Marcos
Published: January 2018

A localização espacial do futuro telescópio James Webb Satellite Telescope (JWST), em uma posição conhecida como L2 em relação ao sistema Sol-Terra, nos remete ao mais celebrado problema da dinâmica, que é o problema de três corpos. Neste trabalho demonstramos o cálculo do posicionamento do telescópio JWST no espaço, cujo lançamento está previsto para ocorrer em 2019. Para isso, consideramos o problema restrito de três corpos, estudando o movimento de grandes massas se movendo sobre atração gravitacional mútua, considerando neste caso que o terceiro corpo (JWST) tem massa desprezível se comparada aos demais. Além de fazer um breve interlúdio histórico, mostramos as forças envolvidas no cálculo da posição do telescópio JWST no espaço, e fornecemos algumas expressões matemáticas simplificadas para tal ponto de Lagrange. Esse estudo envolve o problema da força central explorado em mecânica, o problema dos pontos de lagrange e suas localizações, explorados em astronomia e em dinâmica do sistema solar e a gravitação clássica de Newton.
Digital models: How can dental arch form be verified chairside?
Authors: Tavares Alana , Braga Emanuel , Araújo Telma Martins de
Published: January 2018

ABSTRACT Introduction: Plaster dental casts are routinely used during clinical practice to access maxillary dental arch form and assist on fabrication of individualized orthodontic archwires. Recently introduced, digital model technology may offer a limitation for the obtainment of a dental physical record. In this context, a tool for dental arch form assessment for chairside use is necessary when employing digital models. In this regard, paper print of the dental arch seems thus to be useful. Methods: In the present study, 37 lower arch models were used. Intercanine and intermolar widths and dental arch length measurements were performed and compared using plaster dental casts, digital models and paper print image of the models. Ortho Insight 3D scanner was employed for model digitalization. Results: No statistically significant differences were noted regarding the measurements performed on the plaster or digital models (p> 0.05). Paper print images, however, showed subestimated values for intercanine and intermolar widths and overestimated values for dental arch length. Despite being statistically significant (p< 0.001), the differences were considered clinically negligible. Conclusion: The present study suggests that paper print images obtained from digital models are clinically accurate and can be used as a tool for dental arch form assessment for fabrication of individualized orthodontic archwires.
Self-perceived quality of health and satisfaction by elderly seen by the Family Health Strategy team
Authors: Rigo Lilian , Garbin Raíssa Rigo , Rodrigues José Lucas Sani de Alcântara , Menezes-Júnior Laerte Ribeiro , Paranhos Luiz Renato , Barelli Cristiane
Published: January 2018

ABSTRACT Objective: To verify the profile of elderly followed up by Family Health Strategy teams and the influence of self-reported chronic diseases on demographic variables, describing self-perception and satisfaction with quality of health. Methods: This is a cross-sectional population- based study carried out with 301 elderly residents in two areas of a city in southern Brazil. Data were collected through a questionnaire based on the Health, Well-Being, and Aging Study adapted by researchers, and a playful scale to assess satisfaction with health. For the statistical analysis, the χ2 test was used (p<0.05). Results: Regarding cognitive assessment, the majority was classified as independent (86.4%), not requiring caregiver assistance to answer the questionnaire. The population was predominantly female (55.8%), White (64.8%), married (51.2%), and catholic (82.1%). A total of 47.5% considered their current health status as regular. Regarding satisfaction with health, 72.4% were happy, even reporting having at least one chronic health problem (58.5%). Conclusion: The presence of chronic diseases was reported by most respondents, and the practice of self-medication is significantly more frequent among the aged. Nevertheless, the degree of satisfaction with their health status was predominantly positive, both related to the previous year and compared to others of the same age.
Association between active commuting and elevated blood pressure in adolescents
Authors: Santana Fábio da Silva , Palmeira Aline Cabral , Santos Marcos André Moura dos , Farah Breno Quintella , Souza Bruna Cadengue Coêlho de , Ritti-Dias Raphael Mendes
Published: January 2018

ABSTRACT Objective: To analyze the association between active commuting and blood pressure in adolescents. Methods: This is a cross-sectional study with high school students from public education network in the state of Pernambuco, Brazil. Data from 6039 students (14 to 19 years) were collected using a questionnaire. “Physically inactive” were considered those who reported not to walk or ride a bicycle to and from school on any day of the past week, and/or those who, regardless of the weekly frequency of practice this type of activity, reported the duration of commuting to school was less than 20 minutes (round trip). The high blood pressure was obtained by Omron HEM 742 equipment. Adolescents with high blood pressure were defined as those with higher blood pressure or equal to the 95th percentile for age, sex and height. Regression logistic analyses were used to assess the association between active commuting and high blood pressure, considering adjustments for the following confounders: sex, age, overweight, total physical activity, socioeconomic level, place of residence. Results: The prevalence of high blood pressure was 7.3%, and 79.3% were considered insufficiently active in commuting. There was an association between high blood pressure and active commuting only among those living in rural areas (OR = 6.498; 95% CI = 1.513-27.900), and the same was not observed among those living in urban areas (OR = 1.113; 95% CI = 0.812-1.526). Conclusion: Active commuting can be considered a protective factor for high blood pressure in adolescents living in rural areas.
Estimating Unequal Gains across U.S. Consumers with Supplier Trade Data
Authors: Hottman Colin J. , Monarch Ryan
Published: January 2018

Using supplier-level trade data, we estimate the effect on consumer welfare from changes in U.S. imports both in the aggregate and for different household income groups from 1998 to 2014. To do this, we use consumer preferences which feature non-homotheticity both within sectors and across sectors. After structurally estimating the parameters of the model, using the universe of U.S. goods imports, we construct import price indexes in which a variety is defined as a foreign establishment producing an HS10 product that is exported to the United States. We find that lower income households experienced the most import price inflation, while higher income households experienced the least import price inflation during our time period. Thus, we do not find evidence that the consumption channel has mitigated the distributional effects of trade that have occurred through the nominal income channel in the United States over the past two decades.
Laws against Strikes – The South African Experience in an International and Comparative Perspective (with Corrigendum)
Authors: Laubscher Michael
Published: January 2018

This contribution reviews the book entitled Laws against Strikes – The South African Experience in an International and Comparative Perspective edited by Bob Hepple, Rochelle le Roux and Silvana Sciarra.
Incubation of Synechocystis sp. PCC 6803 colonies for plate reader measurement v1
Authors: Behle Anna , D Miriam
Published: January 2018

In this protocol, the incubation of Synechocystis sp. PCC 6803 colonies on agarplates and further incubation in flasks for further plate reader measurements for fluorescence detection are described. The protocol was handed over by Anna Behle MSc.
Dynamics of markers of markers of acute kidney injury when using epidural block during resection under warm ischemia
Authors: Kit O. I. , Frantsiyants E. M. , Rozenko D. A. , Ushakova N. D. , Dimitriadi S. N. , Pogorelova Yu. A. , Cheryarina N. D. , Kozlova L. S. , Boyko K. P. , Gurnak V. V.
Published: January 2018

Objective: to investigate the time course of changes in the early biomarkers of acute kidney injury in patients with clinically localized cancer during partial nephrectomy, as electively indicated, under thermal ischemia with prior epidural block.

Materials and methods. To analyze the nephroprotective effect of an epidural block in kidney resection with warm ischemia, markers of acute kidney injury (cystatin C, interleukin 18, NGAL, L-FABP and KIM-1) were studied by ELISA in the blood and urine of 35 patients with local cancer with an epidural block (main group) and 37 patients with local cancer without an epidural block (control group) before surgery and 40 min after its beginning and on days 1 and 3 of the postoperative period. All patients were divided into 2 groups by the levels of cystatin C in the blood serum: 1000 ng/ml and lower, and over 1000 ng/ml.

Results. Epidural block during the perioperative period in kidney resection with warm ischemia for patients with local cancer had an obvious nephroprotective effect allowing maintaining the initial renal functional parameters, in contrast to the standard disease management.
Current approaches to selection of the 1st line therapy in patients with metastatic hormone-sensitive prostate cancer
Authors: Alekseev B. Ya. , Andrianov A. N. , Kaprin A. D.
Published: January 2018

Hormone therapy of metastatic prostate cancer (mPC) has been the “golden standard” of treatment since 1941. However, survival rates in patients with this pathology have remained low. Based on the results of newer studies, early start of docetaxel chemotherapy or antiandrogen abiraterone therapy in combination with standard hormone therapy allows to significantly increase survival of patients with mPC. In this review, data from these studies and advisability of docetaxel and abiraterone at the 1st line therapy of mPC are discussed.
Physico-chemical properties of β-diketone phosphorus-containing dendrimers
Authors: Starova Viktoriia , Ianchuk Mykhailo , Zaporozhets Olga , Caminade Anne-Marie
Published: January 2018

Protolytic, absorbance and fluorescence properties of β-diketone phosphorus-containing dendrimers based on cyclotriphosphazene core were studied. Dendrimer solutions in acetone are characterized by intense absorbance band at ≈ 340 nm (ε340≈ 8.5·104L/mol·сm) and fluorescence band with maximum at 440 nm. Position of these maxima does not change in various solvents, unlike the bands of monomer β-diketone. It was found that dendrimer aggregation is accompanied by appearance of a second absorbance band ε400≈ 4.5·103L/mol·сm, by red shift of emission spectra ∆λ ≈ 10 nm and also by decrease in surface tension of acetone solution. Ability of dendrimer aggregates to solubilize organic substrates was observed with the fluorescent indicator acridine.
Aspectos críticos para aplicar con éxito el modelo flipped classroom a la enseñanza de la inmunología: resultados de 5 años de experiencias en la Universidad de Alcalá
Authors: Prieto Martín Alfredo , Díaz Martín David , Lara Aguilera Isabel , Monserrat Sanz Jorge , Oliva Martín Raquel , Barbarroja Escudero José
Published: January 2018

Resumen

Profesores de inmunología de la Universidad de Alcalá hemos implementado en los últimos cinco años el modelo de aula inversa en tres asignaturas del grado de Biología Sanitaria. El porcentaje de alumnos que estudiaron los materiales instructivos (documentos y vídeos) antes de que los temas fuesen tratados en clase ha aumentado desde valores minoritarios en los primeros años a porcentajes cercanos al 100% en los últimos años. La calificación media obtenida por los alumnos en las pruebas de evaluación del aprendizaje ha mejorado en las tres asignaturas en más de una desviación estándar con respecto a la que se obtenía con metodologías expositivas tradicionales antes de la implantación del modelo de aprendizaje inverso. Los porcentajes de alumnos que fracasan han disminuido y han aumentado los porcentajes de alumnos que alcanzan un nivel de maestría (calificación ¿8 en una escala de diez). Los alumnos reconocen desarrollar competencias con las actividades realizadas en los seminarios. El grado de satisfacción de los alumnos también ha aumentado. Concluimos que con el modelo inverso los alumnos universitarios dedican más trabajo no presencial al estudio de sus asignaturas y a consecuencia de ello sus calificaciones en la pruebas de evaluación del aprendizaje mejoran significativamente

 

Abstract

Immunology teachers form Alcala’s University implementes flipped classroom model in the last five years into three immunology courses in sanitary biology university degree. The percentage of students that studied the instructive materials (documents and videos) before class has increased from minority values in the first years to percentages close to 100% in the last years. The mean grade obtained by the classes in the learning assessment exams has increased in the three courses in more than one standard deviation with respect to the original mean obtained in each course with traditional expositive methods before the implementation of the flipped learning model. The percentages of failed students have decreased and those of students that attain mastery levels (grades ¿80% of the maximum grade) have increased. The students recognize that the flipped model helps them to develop competencies in the activities developed in the seminars. The degree of satisfaction with the teaching has also increased We can conclude that university students thanks to the flipped model devote more time of work to the study of flipped courses and as a consequence of this increase in study they learn more and obtain increased grades in the learning assessment exams.
Ser historiador no século XIX. Entre debates, críticas e polêmicas: Pereira da Silva e seu Plutarco brasileiro. * Being a historian in the 19th century. Between debates, criticisms and polemics: Pereira da Silva and his brazilian Plutarch.
Authors: Dall' Agnol Rafael Terra
Published: January 2018

Este estudo tem como objetivo analisar alguns dos debates públicos em que esteve presente a figura do historiador João Manuel Pereira da Silva. Após a publicação de Plutarco Brasileiro, em 1847, o escritor coloca no epílogo do segundo volume da obra algumas das críticas endereçadas ao livro. A partir dos artigos que apareceram em alguns periódicos na imprensa, sobretudo a carioca, pode-se analisar a dimensão pública da obra historiográfica no início do século XIX e, por meio dela, a dimensão ética do historiador, responsável por dizer a verdade sem manipulações ou falsificações em relação ao passado. Paralelamente a esse intento, utilizando como fonte os relatos produzidos acerca do trabalho de Pereira da Silva de forma mais ampla, pretende-se também demonstrar as discussões ocorridas sobre sua a produção histórica, dando especial atenção a um debate sobre a origem paterna do poeta Basílio da Gama.
Sobrevivências na memória: uma possível abordagem visual de um confronto * Survival in the memory: a possible visual approach to a confrontation
Authors: Formolo Deise , Brasil Luísa
Published: January 2018

Este artigo objetiva refletir sobre o uso de imagens como fonte para pesquisas históricas. Realiza-se um exercício de análise de uma fotografia do fotojornalista Carlos Rodrigues, referente ao conflito da luta pela terra ocorrido no estado do Rio Grande do Sul, na cidade de Porto Alegre, em 1990. Utiliza-se, para isso, o conceito de sobrevivência, de Aby Warburg. Essa fotografia pertence a uma série composta de setenta e três fotografias e faz parte do acervo do Sindicato dos Jornalistas do Rio Grande do Sul. Esta análise permite observar o diálogo formal entre registros de conflitos feitos em diferentes tempos históricos.
Apresentação do Dossiê História e Ética: múltiplas e complexas dimensões de um problema historiográfico
Authors: Dos Santos Evandro , Santos Magno Francisco de Jesus
Published: January 2018

Texto de apresentação do Dossiê História e Ética: múltiplas e complexas dimensões de um problema historiográfico, V.6, N.3, 2017.
Hemorrhagic Disease of Newborn: A Prospective Study of Clinical Features and Outcome.
Authors: Gopchade Dr Ajeet
Published: January 2018

Background: Majority of the neonates have a transient deficiency of vitamin K dependant coagulation factors like II, VII, IX and X by 48-72 hours of life. This transient deficiency is resolved by the age of 7-10 days. This transient Vit K dependant coagulation factor deficiency may cause spontaneous bleeding in neonates such bleeding if occurs in between 2nd to 7th day of life is called classical HDN. The other 2 forms of HDN are early onset HDN (Manifesting within 24 hours) and late onset HDN (Occurring between 1-6 months of life). We conducted a prospective study of neonates admitted to our neonatology unit with hemorrhagic disease of newborn to know risk factors and outcome in neonates with HDN.
Aims and Objectives: To study the clinical features and outcome of neonates with hemorrhagic disease of newborn.
Materials and Methods: This was a prospective cohort study comprising of 30 neonates admitted in NICU with the diagnosis of hemorrhagic disease of newborn. HDN associated risk factors, age at presentation, Demographic profile, clinical features, complications and outcomes were studied. Appropriate statistical analysis was done. P-Value less than 0.05 was taken as statistically significant.
Results:  In this study out of 30 neonates diagnosed with hemorrhagic disease of newborn there were 18 (60%) males and 12 (40 %) females with a M:F ratio of 1:0.66. The most common type of HDN was found to be classical type (53.33 %) followed by early onset (12 %) and late HDN (34.77 %). Majority of the infants (83.33%) with HDN were exclusively breastfed and most common site of bleeding were intracranial (23.33 %) and GI bleeding (23.33%). Outcome of neonates showed that 43.33 % babies recovered without any sequele, 13.33 % infants expired and remaining 43.34 % infants had some sequele at the time of discharge.
Conclusion: Hemorrhagic disease of newborn is a common cause of bleeding in a well looking baby. Any well looking baby with bleeding manifestations should be considered to be having HDN (early onset, classical or late onset) unless proved otherwise. Appropriate treatment has an excellent outcome in these babies.
Perinatal Outcome Of Term Pregnancies Complicated By Oligohydramnios
Authors: Chetana Dr , Gopchade A
Published: January 2018

Background: To study the perinatal outcome in Oligohydramnios (AFI < 5) at term & find out incidence of relation of maternal high risk factors.
Methods: A Prospective cohort study of 30 women diagnosed to be having Oligohydramnios on ultrasound at 37 weeks of pregnancy was conducted in an obstetric hospital situated in an urban area. The patients were enrolled in this study on the basis of predefined inclusion and exclusion criteria.  Detailed history was taken in all the patients. General and systemic examination was done. Perinatal Outcome was studied in terms of birth asphyxia, presence of anomalies, need for admission to NICU and neonatal mortality. Odds ratio were calculated at appropriate associations. P < 0.05 was considered as significant. The data was tabulated and analyzed using SPSS 16.0 version software.
Results: Our study found that Oligohydramnios at term pregnancy was associated with increased incidence of nonreactive NST, meconium stained amniotic fluid, birth asphyxia, respiratory distress immediately after birth, congenital anomalies, need for admission to NICU and neonatal mortality.
Conclusions: Oligohydramnios diagnosed on ultrasound at or after term (37 weeks) is associated with adverse perinatal outcome. The possibility of congenital anomalies, birth asphyxia and need for NICU admission in immediate postnatal period makes it necessary that such patients be delivered at an appropriate centre having NICU facilities.
Identification of non-equilibrium growth for Bitcoin Exchange rate: Mathematical derivation method in Islamic Financial Engineering
Authors: Bakar Nashirah Abu , Rosbi Sofian
Published: January 2018

Crptocurrency is a type of digital currency that using decentralized method for validating transaction. In the same time, the user of the Bitcoin is protected using hash algorithm. The value of Bitcoin is increased sharply in 2017 that creates much attention from investors. The objective of this study is to develop the mathematical model evaluate growth of Bitcoin exchange rate. The data selected in this study are starting from 1st January 2017 until 10th December 2017. This study validates the normality distribution of data using graphical and numerical method. Graphical method indicates the first difference of data distribution is a non-normal distribution. Then, Shapiro-Wilk statistical test confirmed that first difference of data distribution deviate from normal distribution. The non-normal distribution occurs because of the presence of outliers. Next, this study validates the mathematical modeling fordata trend using quadratic formula. Result indicates that the growth of Bitcoin exchange rate in moving towards non-equilibrium point. This concludes that the growth of the Bitcoin exchange rate is in unstable region.  The contribution of this study is to help investors to understand the nature of Bitcoin exchange rate. This study performed analysis that helps investors to develop more efficient investment portfolio in gaining better profit and reducing loss