bluuebunny/crossref_metadata_2025 huggingface dataset:
Real-world effectiveness of a single-day regimen for transcranial magnetic stimulation using Optimized, Neuroplastogen-Enhanced techniques in Depression (ONE-D)
Authors: Vaughn Donald A , Marino Brooke , Engelbertson Alex , Dojnov Aleksandra , Weiss Nick , Vila-Rodriguez Fidel , Nanos Georgine , Downar Jonathan
Published: December 2024

Background: Conventional transcranial magnetic stimulation (TMS) regimens are logistically burdensome, requiring days or weeks of clinic visits. Here we describe a TMS regimen enabling delivery of an entire therapeutic course in a single day.
Methods: This retrospective case series reports outcomes for an optimized, neuroplastogen-enhanced depression (ONE-D) treatment regimen delivering 600-pulse iTBS (120% MT) targeting left DLPFC via scalp heuristic, every 30 minutes for 20 sessions in 9.5 hours, enhancing neuroplasticity via single-dose d-cycloserine (125 mg) and lisdexamfetamine (20 mg), off-label, given 1 hour pre-treatment. 32 TMS-eligible adults with medication-resistant unipolar depression underwent the ONE-D regimen, with assessments on day-of-treatment then weekly x 6 weeks (HDRS-17, BDI-II, PHQ-9, and GAD-7).
Results: Every patient completed the regimen successfully, with no serious adverse events (mean scalp discomfort, 5.8±2.1/10). Response was not immediate but followed an exponential-decay trajectory over the 6-week followup: mean weekly scores of 22.6±5.3(baseline), 13.5±6.4, 10.6±6.4, 7.9±4.9, 6.6±4.9, 6.3±4.8, 5.5±4.2 (HDRS-17), 37.5±9.0(baseline), 23.8±12.2, 17.1±11.1, 14.1±11.2, 11.0±8.7, 9.5±8.2, 7.6±7.8 (BDI-II,) 18.4±3.5(baseline), 11.4±5.1, 9.4±5.7, 6.9±5.2, 6.0±3.9, 5.3±4.0, 4.6±4.2 (PHQ-9), 14.3±5.2(baseline), 8.7±4.5, 6.4±5.0, 4.3±4.0, 3.8±3.6, 3.3±3.3, 3.1±2.7 (GAD-7). Response / remission rates (cross-sectional, not aggregated) were 90.3% and 74.2% (HDRS-17), 93.5% and 71.0% (BDI-II), 90.3% and 58.1% (PHQ-9), 93.3% and 76.7% (GAD-7) at week 6, and 92.6% and 77.8% (HDRS-17), 92.3% and 73.1% (BDI-II), 86.4% and 65.4% (PHQ-9), 91.7% and 80.0% (GAD-7) at week 12.
Conclusion: Delivery of an effective TMS course in one day appears feasible, safe, and well-tolerated. With neuroplastogen-enhancement, despite non-personalized, scalp-based targeting, the response and remission rates appeared robust and sustained in representative clinical populations. Follow-up studies may allow further acceleration of the regimen and generalization to other TMS indications.
Nicking Enzyme Assisted Amplification Combined with CRISPR-Cas12a System for One-Pot Sensitive Detection of APE1
Authors: Dai Wei , Wang Han , Xiao Xian , Li Yiyuan , Zhou Jiahui , Jiang Dayang , Luo Yangkang , Xiao Xianjin , Li Longjie , Yu Jie , Yan Bei
Published: December 2024

Apurinic/apyrimidinic endonuclease 1 (APE1) is a critical enzyme in the base excision repair (BER) pathway, essential for preserving cellular equilibrium. Variations in APE1 activity within blood or tissues can provide significant insights for clinical cancer screening and disease diagnosis. Consequently, the detection of APE1 activity is critical for clinical diagnostics. However, there is currently a deficiency in rapid, straightforward, and sensitive methods for APE1 detection. To address this issue, we developed a method that integrates nicking enzyme assisted amplification (NEAA) with CRISPR-Cas12a signal amplification, enabling one-pot detection of APE1 activity. This method utilizes NEAA to produce a substantial quantity of target DNA that is complementary to the crRNA, thereby triggering the trans-cleavage activity of Cas12a. The activated Cas12a then amplifies and emits signals by cleaving the reporter probe. Our strategy allows for the swift and precise detection of APE1, with a detection threshold of 1×10− 6 U/mL and a linear detection range of 5×10− 6 to 0.1 U/mL. It has been effectively utilized for the detection of APE1 in biological samples.
Adiponectin influences the behavior of stem cells in hormone-resistant breast cancer
Authors: Naimo Giuseppina Daniela , Forestiero Martina , Giordano Francesca , Leonetti Adele Elisabetta , Gelsomino Luca , Panno Maria Luisa , Ando Sebastian , Mauro Loredana
Published: December 2024

Background: Overcoming endocrine-resistance is the major challenge in treating Estrogen receptor (ER)-positive breast cancer. Breast Cancer Stem Cells (BCSCs) are blamed to be the driving force behind poor clinical outcomes and low therapeutic response. Notably, tumor microenvironment (TME) exerts a selective pressure on BCSCs behavior. The most prevalent cellular component of the TME is represented by adipocytes, which secrete reduced levels of adiponectin in obesity, promoting ERα-positive breast cancer growth and progression. Here, we examined the impact of low adiponectin levels on the enrichment of BCSC subpopulations and the underlying molecular mechanisms by which this may contribute to the maintenance of hormone-resistance in breast cancer.
Methods: MCF-7 wild type (WT) and tamoxifen-resistant (TR) cells were grown as mammospheres. Mammospheres Forming Efficiency (MFE) and self-renewal were evaluated by mammospheres count. Flow cytometry analysis were performed to assess CD44+/24- cell ratio, ALDH1 expression, apoptosis, ROS production, and mitochondrial membrane potential. mRNA levels of stemness, epithelial to mesenchymal transition (EMT), proliferation and cell cycle markers were quantified by qRT-PCR. Western blotting was used to detect protein levels. DNA quantitation was carried out to investigate growth rate. nLC-MS/MS was employed to profile and compare the proteome of BCSCs. The differentially expressed proteins (DEPs) were intersected with data from MetacoreTM dataset.
Results: Our study demonstrated that adiponectin increased the percentage of CD44+/CD24-/ALDH1+ stem-like cells in TR MCF-7 compared to hormone-responsive WT MCF-7 mammospheres. Moreover, adiponectin induced cell cycle arrest in G0/G1 phase, supported by cyclin D1 and Ki67 decreased levels, concomitant with an increased expression of cyclin-dependent kinase inhibitors p21 and p27 in TR MCF-7 cells. Consistent with these data, we observed an enhanced ability of adiponectin-treated TR MCF-7 cells to escape from apoptosis, sustained by reduced ROS production and the maintenance of mitochondrial membrane potential, critical to prevent cytochrome C release.
Conclusions: Overall, we have shown that low levels of adiponectin promote stem-like features in TR MCF-7 cells, contributing to select the hormone-resistant phenotype. Understanding the molecular mechanisms through which low levels of adiponectin potentiate stemness in endocrine-resistant cells may disclose novel therapeutic approaches to treat obese patients developing hormone-resistant breast cancer.
Awareness of, practical experience in, and education need for health advocacy in Japan: a preliminary study among physicians in Japan
Authors: Mizuma Kimiko , Amitani Marie , Sakiyama Hayato , Ibusuki Rie , Owaki Tetsuhiro
Published: December 2024

Background Health advocacy, as performed by physicians, is an important global agenda for tackling health inequities, especially in the primary care area. However, few physicians are trained be able to perform health advocacy in Japan. This descriptive preliminary study aimed to clarify the current situation regarding health advocacy among Japanese physicians and propose specific strategies for its dissemination.Methods A questionnaire survey was distributed to 1,296 medical institutions in Kagoshima Prefecture to clarify Japanese physicians’ awareness of, practical experiences in, and education need for health advocacy.Results Physicians strongly perceived the need for health advocacy on the micro, meso, and macro levels (95.3%, 82.4%, and 77.7%, respectively). However, about 90% of the physicians did not actually put meso- and macro-level health advocacy into practice. Overall, specific social issues were less recognized as targets of health advocacy as its range of actions broadened from the micro to the meso and to the macro levels. And even given that overall trend, different trends in awareness of the need for and actual practice in health advocacy were observed among each social issue. In total, 73.6% of the physicians had never heard the term “health advocacy”, and 45.9% did not think it was their responsibility. However, 69.6% of the physicians showed a positive attitude toward participating in health advocacy education. Over 62% of the physicians supported undergraduate and lifelong medical education as effective dissemination measures of health advocacy among Japanese physicians. Notably, however, the physicians who were more likely to be rooted in primary care expressed less willingness to participate in lifelong educational opportunities.Conclusions The findings of this study suggest that feasible lifelong medical education is needed for Japanese physicians to acquire the knowledge, attitudes, and practical skills necessary to perform health advocacy on the meso and macro levels. Furthermore, the introduction of health advocacy as a theme of undergraduate medical education in Japan is needed. To develop both general theoretical research and practical educational strategies research is required that can lead to effective health advocacy solutions for health inequities.
Exploring Lichen Derived Compounds for Therapeutic Potential in Diabetes Management
Authors: Abirami S. , Hemashenpagam N.
Published: December 2024

Nature has been a profound source of medicinal agents for millennia, with numerous modern drugs derived from natural sources. Many of these discoveries stem from traditional medicine practices. Plants, in particular, are rich in secondary metabolites like tannins, terpenoids, alkaloids, and flavonoids, known for their antimicrobial properties. Among these, lichens, which are symbiotic organisms consisting of a fungus and an alga, present significant potential for medical exploration. Studies have shown that lichen metabolites, such as depsides, depsidones, and usnic acid, exhibit activity against mycobacteria and Gram-positive bacteria. With the growing ineffectiveness of some conventional drugs, there is renewed interest in lichen compounds. This study focuses on the antimicrobial and antioxidant activities of lichens from Ooty, Tamil Nadu, India. Extracts from these lichens were analyzed using LC-MS and various assays, including phenol content, FRAP, ORAC, and DPPH, revealing substantial antioxidant activity. In vitro tests for inhibiting pancreatic lipase, α-glucosidase, and α-amylase, along with in silico predictions of pharmacokinetic properties, toxicity risks, and molecular interactions, demonstrated notable inhibitory potential. This research enhances our understanding of bioactive compounds in lichens from temperate and polar regions and highlights their potential as natural alternatives for treating diseases linked to oxidative stress and metabolic syndrome.
Evaluation of water quality by Fuzzy DEMATEL and statistics analysis
Authors: Askari Kaveh Ostad Ali , Kianmehr Peiman
Published: December 2024

Significant deterioration in water quality produced by natural components and human activities can mark anthropological health and ecologies. Therefore, it is significant to check the water quality on a regular basis. This study emphases on the location of 21 water components and 14 diverse water monitoring stations along the Shirin rood River. Multivariate analysis is used in this study. The PCA examinesthe origin of each parameter that contributes to river pollution. The AHC technique is used to group all water qualitymonitoring stations depend on the level of river contamination regions. The study then expands the Fuzzy Decision Trail and Evaluation Institute (FDEMATEL) to discovery causal relationships amongst river pollutants. The results display that 5 key PCs with 53.128% of total alteration were gained from the water quality information. AHC categorizes three clustered areas as low, medium and high contamination. The results of this study will help disclose significant information about river water quality in order to managepollution sources and thereby maintaininhabitants and ecosystem health.
Unveiling the Hidden: Prevalence of Dystrophic Calcification in Digital Orthopantomograph Through a Retrospective Study
Authors: Jain Swasti , Singh Mohitpal , Mathur Hemant
Published: December 2024

OBJECTIVE- Soft tissue calcifications in the head and neck region are a rare occurrence that are frequently seen on digital panoramic radiographs. This article delves into panoptic exploration to examine and evaluate the prevalence of dystrophic calcification and other soft tissue calcifications in digital orthopantomographs across diverse patient population through a retrospective analysis. METHOD AND METHODOLOGY-A systematic analysis of a small dataset of 300 patients between the ages of 12 to 74 years were studied using their digital OPGs. These radiographs were utilized to focus on identifying and categorizing dystrophic calcifications, and other soft tissue calcifications which includes calcified stylohyoid ligament, tonsillolith, carotid artery calcification, sialolith of submandibular gland, rhinolith, phlebolith and antrolith based on prevalence according to gender, age and site using Chi square test and ANOVA test. RESULTS- Findings of the study showed that soft tissue calcifications including dystrophic calcifications are remarkably common manifestation in digital OPGs. Notably, the prevalence of these calcifications were found more in male than in female. Presence of styloid ligament calcification(28.7%) and carotid artery calcification(16.7%) were the two most common soft tissue calcifications found in oral maxillofacial region. Additionally, a significant percentage of cases showed calcifications in the carotid arteries, raising serious questions regarding vascular consequences.Other soft tissue components showed distinct patterns of calcification like sialolith, phleboliths, rhinoliths, antrolith and tonsillolith emphasize more on their potential diagnostic use. Also, the prevalence of all the calcifications increased with increase in age.[15] CONCLUSION-Soft tissue calcifications are frequently seen on panoramic radiographs. Dentists should be able to recognize it and determine the differential diagnosis of the primary soft tissue calcifications in the dentomaxillofacial region when it occurs. Early diagnosis of atherosclerotic conditions and prompt guidance regarding the patient's medical condition may be of high importance in patients’ health.
Empirical Evaluation for Cricket CommentaryDecoder
Authors: BODKHE SAHIL , Rajasekaran Nandhini , Nagesh Chinmay
Published: December 2024

Cricket is not just a sport but a global phenomenon, attracting billions of fans and generating immense revenue through broadcasting rights, streaming platforms, and fantasy sports applications. With the advent of professional leagues like the Indian Premier League (IPL) and Big Bash League (BBL), cricket has become a data-rich and analytics-driven game. Real- time event classification from live commentary is crucial for powering these ecosystems, from enhancing viewer experiences to enabling fantasy leagues and predictive analytics. This project aims to develop a real-time cricket commentary decoder to classify events accurately from unstructured and informal textual commentary. Cricket commentary often includes colloquial lan- guage, ambiguous phrases, and context-dependent expressions, which traditional rule-based Natural Language Processing (NLP) techniques struggle to handle effectively. The solution incorpo- rates innovative strategies to address sense disambiguation by intentionally removing clear event-indicative keywords, thereby simulating real-world complexity. By tackling the limitations of rule-based systems such as their over reliance on explicit keywords and inability to handle ambiguous contexts, the system achieves robust event classification for runs, outs, extras, and dots game actions. Designed to seamlessly integrate with real- time sports tracking applications, the decoder enables dynamic updates and API calls. By balancing computational efficiency with classification accuracy, this project not only addresses the technical challenges of decoding live commentary but also supports the growing role of data and analysis in the modern cricket ecosystem. To overcome these challenges, the proposed system employs advanced machine learning methods, including LSTM, GRU, SVM, Logistic classifiers, and boosting techniques like LightGBM.
Implementation of All-optical Trinary State Half-adder Using Semiconductor Optical Amplifier Supported by Simulation Experiment
Authors: Mondal Tanmay , Biswas Subhendu
Published: December 2024

The bottleneck of electronic systems due to the increase of requirements of very large bandwidth and speed was removed by photonic systems owing to its inherent parallelism and high speed of operation which also made it a strong contender in optical data processors. In a Photon one can encode digital information in its Amplitude, Frequency, Phase and Polarization properties. As frequency is the basic characteristic of light, so frequency encoding principle is the most reliable one among all other encoding principles. In Frequency encoding, the schemes become immune to noise. The frequency of light does not change normally after reflection, refraction or absorption. It can be used in several faithful high bandwidth real-time optical logic processors which in the future can dominate the optical communication and data processing systems. For different frequency-shifting operations, we can use Semiconductor Optical Amplifier (SOA) in real-time. In this proposed scheme, using the SOA, the Trinary state-based half adder has been proposed for optical communication, where in the Trinary state ‘-1’ logic state is represented by a frequency ν1 then the ‘0’ state is represented by another frequency ν2 and the ‘1’ logic state is represented by a frequency ν3. The photonic schemes proposed are also being verified by Matlab Simulink simulation.
СОВЕТСКО-ИТАЛЬЯНСКОЕ ВЗАИМОДЕЙСТВИЕ В КОНЦЕ 1950-Х ГГ.: ЭКОНОМИЧЕСКИЙ И КУЛЬТУРНЫЙ АСПЕКТЫ
Authors: Гиголаев Г.Е.
Published: December 2024

Культурное и экономическое взаимодействие между государствами, входившими впротивоборствующие военнополитические блоки в годы холодной войны, тесно связано с понятиями мягкая сила и мирное сосуществование, возникшими взападном и восточном политическом лексиконе, соответственно. Активизация экономических и культурных связей между СССР и Италией на рубеже 1950х1960х гг. способствовала налаживанию политического взаимодействия, хотя оно было обусловлено и чисто политическими причинами, связанными с ранней разрядкой в отношениях между СССР и странами Запада.

Cultural and economic interaction between states that were part of the opposing militarypolitical blocs during the Cold War years is closely related to the concepts of soft power and peaceful coexistence that emerged in the Western and Eastern political lexicon, respectively. The intensification of economic and cultural relations between the USSR and Italy at the turn of the 1950s 1960s. contributed to the establishment of political interaction, although it was also due to purely political reasons related to early dtente in relations between the USSR and Western countries.
РУССКАЯ КУЛЬТУРА В ОБЩЕЕВРОПЕЙСКОМ КОНТЕКСТЕХУДОЖЕСТВЕННОЕ НАСЛЕДИЕ РУССКОГО ЗАРУБЕЖЬЯВ ВЕЛИКОБРИТАНИИ
Authors: Щеблыгина И.В.
Published: December 2024

В истории процесса открытия и признания русского искусства за рубежом огромная роль принадлежит русской художественной эмиграции. Продолжив отечественную культурную традицию, она вписала свою страницу в историю мировой художественной культуры. Статья посвящена одному из малоизученных аспектов русского культурного наследия в мире творческому наследию художников русского зарубежья в Великобритании. Русское художественное собрание в музее Эшмолеан и доммузей Л.О. Пастернака в Оксфорде, мозаики Б. Анрепа, украшающие художественные галереи и общественные здания в Лондоне, серия панно Л. Бакста в музее Уодесдон, витражи Марка Шагала в графстве Кент все это, созданное русскими художниками, органичная часть культурного пространства Великобритании.

Russian artistic emigration has played an important part in the historic process of discovery and recognition of Russian arts. Having followed Russian cultural traditions the emigration wrote down its own page in the history of world artistic culture. This article speaks about the artistic heritage of Russian emigration artists in the United Kingdom which appeared to be one of little studied aspects of Russian cultural heritage in the world. Russian arts collection of Ashmolean Museum, memorial house of Leonid Pasternak in Oxford, mosaics by Boris Anrep decorating art galleries and public buildings in London, series of canvas wall panels by Leo Bakst in Waddesdon museum, stainedglass panels by Marc Chagall in Kent county all these creations by Russian artists blended in with the culture of Great Britain.
МОЛОДЕЖЬ ЮГА РОССИИВ ЧЕХОСЛОВАЦКОЙ РЕСПУБЛИКЕ (1920–1930-е гг.)
Authors: Барбарунова З.А. , Копpшивова А.В.
Published: December 2024

Данная работа представляет собой опыт историкосоциологического исследования групп эмигрантов в возрасте до 35 лет. Рамки исследования ограничиваются уроженцами Области Войска Донского, Области Терского казачьего войска, Кубанской области и Черноморской губернии.

This work is an example of the historically sociological research, analyzing the groups of Don, Kuban and Terek immigrants up to 35yearold, who came to Czechoslovakia to study in the period of the Russian auxiliary actions of Czechoslovakia. These groups include the young generation of Cossacks and urban citizens from the Don, Kuban, Terek, and also Czech colonists from the Black Sea provinces.
ИСПАНСКИЕ ИНТЕЛЛЕКТУАЛЫ И РОССИЯ НАЧАЛА ХХ ВЕКАМЕЖДУ ЛИТЕРАТУРОЙ И ЖИЗНЬЮ
Authors: Гранцева Е.О.
Published: December 2024

В статье сделана попытка проанализировать место России в испанском интеллектуальном и общественном дискурсе начала ХХ века, выделить ключевые феномены и факторы влияния, определить точки пересечения и противоречия в восприятии испанцами русской культуры (прежде всего, литературной и идейной ее составляющих) и внешнеполитического образа Российской империи.

The article attempts to analyze the place of Russia in the Spanish intellectual and social discourse of the early twentieth century, to identify key phenomena and factors of influence, to identify points of intersection and contradictions in the Spaniards perception of Russian culture (first of all, its literary and ideological components) and the foreign policy image of the Russian Empire.
СТАРАЯ РУССКАЯ ПРОФЕССУРА В ЭМИГРАЦИИА.И. ИГНАТОВСКИЙ (1875-1955)
Authors: Васильев К.К.
Published: December 2024

Впервые вводятся в научный оборот архивные источники, позволяющие восполнить ряд пробелов в биографии профессоратерапевта А.И.Игнатовского, научная деятельность которого связана с Петербургской военномедицинской академией (18991908), а также с университетами: Новороссийским (Одесса 19081911), Варшавским (19111917), Донским (РостовнаДону 19171920), а после политической эмиграции с университетами в Белграде (19221941, 19441946) и Скопье (19471955).

Recently discovered archival documents allow to fill a number of gaps in the biography of Professor therapeutist Alexander Ignatovsky, whose academic work was connected with the Petersburg Military Medical Academy (18991908), as well as with the Universities of Novorossiysk (Odessa 19081911), Warsaw (19111917), Donskoy (RostovonDon 19171920), and, during the years of his exile, with the universities in Belgrade (19221941, 19441946) and Skopje (19471955).
Е. Ф. МАКСИМОВИЧ – ПРЕДСТАВИТЕЛЬ “ВТОРОГО ПОКОЛЕНИЯ”ИСТОРИЧЕСКОЙ НАУКИ РУССКОГО ЗАРУБЕЖЬЯ
Authors: Волошина В.Ю. , Корзун В.П.
Published: December 2024

В статье на примере судьбы и творчества Е.Ф. Максимовича поставлена проблема факторов успеха и неуспеха профессиональной карьеры представителей второго поколения историков русского зарубежья. Авторы пришли к выводу, что условия и образ жизни сказались на стиле научного творчества и отметили дрейф от научного к публицистическому. Эти обстоятельства во многом задавали горизонты видения исторической науки в метрополии, она воспринималась как раздражающее чужое. Статья написана с использованием материалов отечественных и пражских архивов, а также научных публикаций и эмигрантской периодической печати.

The article is focused on the life and work of E.F. Maksimovic and discusses the factors of success and failure of the professional career of the second generation of migr historians of the Russian diaspora. The authors concluded that the style and living conditions affected the style of academic work and noted the drift from academia to journalism. These circumstances largely set the horizons of the vision of historical discipline at home, which was perceived as an annoying alien. The article used materials from Russians and Prague archives, as well as academic publications in the emigrant periodicals.
ЗИГЗАГИ СУДЬБЫ ИНЖЕНЕРА ВЛАДИМИРА БАРРИ
Authors: Мария В.К.
Published: December 2024

Статья посвящена истории жизни инженера путей сообщения Владимира Андреевича Барри (18761959), который, оказавшись в эмиграции в Маньчжурии, служил профессором Харбинского политехнического института. Барри был типичным представителем русской интеллигенции, сформировавшейся до революции: высокообразованный, не обошедший увлечений социальными вопросами, но беспомощный в политике. Его биография является отражением противоречивых событий российской истории, состоит из неожиданных поворотов, а жизненный путь Барри является примером служения раз и навсегда избранному делу. Статья основана на неопубликованных материалах архивов РГИА, ЦГИА СПб, ГАХК.

The article discusses the life story of a transport engineer Vladimir Andreyevich Barry Статья (18761959) who emigrated to Manchuria and taught at the Harbin Polytechnic Institute. Barry was a typical Russian prerevolutionary intellectual: highly educated, not without interest in social issues, but rather helpless in the world of real politics. His life reflects dramatic events of the Russian history, is full of unexpected turns but also serves as an example of dedication to ones life goal. The article is based on unpublished documents from the Russian State Historical Archive, Central State Historical Archive at St Petersburg, State Archive of the Khabarovsk region.
РУССКИЙ ИСТОРИК И СОЦИОЛОГ А. П. ЩАПОВО ПРИЧИНАХ ПОДЧИНЕННОГО ПОЛОЖЕНИЯ ЖЕНЩИНЫВ РОССИЙСКОМ ОБЩЕСТВЕ
Authors: Батуренко С.А.
Published: December 2024

В статье рассматриваются описанные известным русским историком и социологом географического направления Афанасием Прокопьевичем Щаповым причины подчиненного положения женщины в России. А.П.Щапов был одним из первых социологов, поставивших в XIX веке вопрос о роли женщины в развитии общества, об особенностях интеллектуального развития русского народа в целом, и его влиянии на сложное социальное положение женщины.

The article considers the reasons of the subordinated position of the women in Russia described by Afanasy Prokopyevich Shchapov, a famous Russian historian and the sociologist of the geographical school. Shchapov was one of the first 19th century sociologists who raised a question of the womans role in social development, about the intellectual development of the Russian people in general, and its influence on a complex social status of women.
ИСТОКИ (ГИПОТЕТИЧЕСКОЙ) РОССИЙСКОЙ ШКОЛЫМЕЖДУНАРОДНЫХ ОТНОШЕНИЙ В XIX ВЕКЕ
Authors: Торкунов А.В.
Published: December 2024

Статья посвящена поиску истоков формировавшейся самобытной школы международных отношений в России в конце XIX начале XXв. Такие истоки видятся, вопервых, в стремительном развитии военной стратегии и географии в Российской империи, а вовторых, в бурной общественнополитической дискуссии о вариантах внешнеполитического развития Российского государства в описываемый период. Можно предположить, что на пересечении этих двух трендов в первой половине XXв. могла зародиться уникальная российская школа международных отношений, которая заняла бы важное место в ряду других национальных традиций англосаксонской, немецкой, французской и др. Однако ее естественное развитие было прервано драматическими событиями XXвека, и теперь можно только догадываться, на какие ракурсы мировой политики такая школа могла бы обратить свое внимание.

The article looks into the origin of a distinctive School of International Relations in Russia in the late 19th early 20th c. Its emergence can be seen firstly in the rapid development of military strategy and geography in the Russian Empire and secondly in the turbulent social and political debate about the options for the development of the Russian foreign policy in the period described. It can be assumed that the intersection of these two trends in the first half of the 20th century could create a unique Russian School of International Relations, which would occupy an important place alongside other national traditions AngloSaxon, German, French, etc. However, its natural development was interrupted by the dramatic events of the beginning of the 20th century. Now, one can only guess what facets of world politics such a school could turn its attention to.
ВРЕМЯ ОЛЬДЕНБУРГА. POST FACTUM1. Е.Г. Ольденбург и академическое сообщество в деле сохранения научного наследия академика С.Ф. Ольденбурга
Authors: Ананьев В.Г. , Бухарин М.Д.
Published: December 2024

Академик Сергей Федорович Ольденбург, крупнейший российский историк первой трети XX в. востоковед, искусствовед, филолог, этнограф будучи Непременным секретарем Академии наук (ПАН/РАН/АН СССР), фактически руководил российской академической наукой в 19041929 гг. Административная нагрузка не позволила ему опубликовать при жизни главный свой труд Описание пещер Чанфодун близ Дунхуана. После кончины С.Ф.Ольденбурга его вдова Е.Г.Ольденбург взяла на себя подвижнический труд по написанию биографического очерка С.Ф. Ольденбурга и попытке организовать силами коллег по АН СССР издание его труда. Ее переписка официальная с президентом АН СССР В.Л. Комаровым и Непременным секретарем АН СССР Н.П. Горбуновым и частная с крупнейшими учеными И.Ю.Крачковским и В.И.Вернадским и его супругой, представляющая собой диалог из прошлого с новой эпохой, полной лишений и равнодушия, в попытке продлить время Ольденбурга, будет опубликована во 2й части данной работы (вып. 69).

Sergey Fedorovich Oldenburg was an eminent Russian historian of the first third of the 20th century an orientalist, art historian, philologist, ethnographer as the Permanent Secretary of Academy of Sciences (Imperial, Russian, Academy of Sciences of the USSR), he actually directed Russian academic science in 19041929. Administrative burden did not allow him to publish his main work Description of the Caves Chanfodun near Dunghuang. After S.F. Oldenburgs death, his widow, E.G. Oldenburg, has undertaken selfless work to perpetuate Oldenburgs memory by editing of the Description of the Caves with the help of the colleagues of Oldenburg in the Academy, and by writing his biography. Her correspondence official with the President of the Academy of Sciences of the USSR V.L. Komarov and Permanent secretary N.P. Gorbunov and private with famous scholars of the first half of the 20th century, I.Yu Krachkovsky and V.I. Vernadsky and his spouse, represents dialogue of the past with the new era, full of deprivations and indifference, in attempt to prolong The time of Oldenburg.
СОВЕТСКИЕ ИСТОРИКИ. ПОКОЛЕНИЯ И ТРАДИЦИИРазмышления по поводу книги Л.А. Сидоровой«Советские историки: духовный и научный облик»
Authors: Арзаканян М.Ц.
Published: December 2024

Статья представляет размышления автора над книгой Л.А.Сидоровой, посвященной советским историкам трех поколений. В монографии прослежено влияние на их жизнь и творчество религии, художественной литературы, искусства, музыки.

The article presents the last monograph by L.A.Sidorova, which is devoted to three generations of Soviet historians. The book traces the influence of religion, fiction, art and music on their life and scientific work.
(НЕ)СВОЕВРЕМЕННЫЕ МЫСЛИ И СУЖДЕНИЯО ПРАГМАТИКЕ УТОПИЙ
Authors: Паниотова Т.С. , Kореневский А.В.
Published: December 2024

В статье рассматриваются итоги Второй Всероссийской (с международным участием) конференции Утопические проекты в истории культуры на тему Город Солнца: в поисках идеального локуса (к 450летию со дня рождения Томмазо Кампанеллы), состоявшейся в Южном федеральном университете (РостовнаДону) 68 ноября 2018 г. представлен широкий круг проблем, отраженных в докладах, дискуссиях и круглых столах, прошедших в рамках конференции.

The article deals with the results of the Second AllRussian (with international participation) conference Utopian projects in the history of culture on the topic City of the Sun: in search of the ideal locus (for the 450th anniversary of the birth of Tommaso Campanella) held at Southern Federal University (RostovonDon) November 68, 2018 with the financial support of the Russian Foundation for Basic Research a wide range of issues reflected in the presentations of participants, discussions and round tables held during the conference is presented and analyzed.
NEGOTIATING THE RULE OF LAW AND HUMAN RIGHTS IN INTERFAITH MARRIAGE REGISTRATION IN CONTEMPORARY INDONESIA
Authors: Salam Nor , Zaman Jamrud Qomaruz
Published: December 2024

The Supreme Court Circular Letter Number 2 of 2023, which prohibits the registration of interfaith marriages in Indonesia, aims to provide legal clarity following longstanding debates fueled by the abstract nature of existing norms. While the circular seeks to enforce uniformity in marriage regulations, it raises concerns regarding human rights, especially the rights to freedom, equality, and the pursuit of happiness, which are central to democratic governance. This article seeks to examine interfaith marriage registration by utilizing normative and human rights perspectives to explore its legal foundations and implications within Indonesia’s modern context. The analysis highlights tensions between national law and international human rights conventions, suggesting that interfaith marriage registration should be recognized as a legal right that upholds citizens’ freedoms, religious autonomy, and equality before the law. By situating interfaith marriage within Indonesia’s framework of Islamic jurisprudence (fiqh), legal statutes, and human rights conventions, this article highlights the importance of balancing legal uniformity with the protection of individual rights in a democratic, constitutional state.
Economic Policy Uncertainty in the United States: Does It Matter for Equity, Commodity and Cryptocurrency Markets?
Authors: Zia Ur Rehman  , Wing-Keung Wong  , Naveed Khan  , Hassan Zada  , Hassan Raza
Published: December 2024

In recent years, the issue of worldwide uncertainty has gained more attention in academic literature. Therefore, the current study examines how the United States (U.S.) economic policy uncertainty (EPU) affects various stock indices, commodities and cryptocurrencies. This study takes data on stock indices and commodities from February 2005 to December 2023 and data on cryptocurrency from October 2017 to December 2023. For estimations, we employ the Quantile-on-Quantile regression (QQR) approach to investigate the impact and to understand how changes in EPU affect stock indices, commodities, and cryptocurrency returns at different levels of quantiles. The findings reveal that EPU has a negative impact on the stock indices and cryptocurrencies. For stocks, high uncertainty leads to more volatility, while EPU exhibits higher volatility for cryptocurrencies, indicating sensitivity to policy changes. Similarly, commodities react differently to the U.S. EPU, while gold tends to appreciate in uncertain times. Furthermore, we employ quantile regression for robustness check, and the findings validate the outcome of QQR at various levels of quantiles from lower to higher. Moreover, the findings of this study are helpful for investors, portfolio managers, and policymakers to develop better investment strategies and effectively manage risks across different asset classes.
Digital Transformation and Corporate Innovation: Empirical Discovery Based on Machine Learning
Authors: Tingqian Pu  , Yujie Li  , Abdul Hadi Zulkafli
Published: December 2024

With the flourishing development of the digital economy, the phenomenon of digital transformation at the firm level has attracted scholars’ attention regarding its impact on microeconomic activities. However, whether the transformational changes induced by digital technologies affect corporate innovation and the underlying mechanisms have not been fully explored. Based on panel data from Chinese listed firms spanning from 2012 to 2021, this paper constructs a measure of digital transformation using machine learning techniques and investigates its relationship with corporate innovation. The findings suggest that digital transformation effectively promotes corporate innovation, a result robust to a battery of sensitivity checks. Mechanism analysis reveals that digital transformation significantly enhances innovation by increasing R&D input and improving innovation efficiency. Further analysis indicates that the innovation-promoting effect of digital transformation is mainly manifested in high-quality innovation output, with greater benefits observed for state-owned enterprises and non-high-tech industry enterprises. Overall, our study provides valuable policy insights for enhancing innovation levels among enterprises in developing countries like China through digital transformation strategies.
Sovereign Bond Holdings under Bank Competition in Vietnam
Authors: Japan Huynh
Published: December 2024

This article investigates the impact of bank competition on the holdings of sovereign bonds. Using bank-level data from Vietnam for 2007–2021, we design various proxies to indicate bank competition and apply the system generalized method of moments (GMM) to conduct main regressions. We find that banks are more likely to hold domestic treasury securities in response to greater market competition. We add strength to our analysis by conducting subsample checks to allow for potential structural breaks due to the financial and COVID-19 pandemic crises. In addition, we find that sovereign debt holdings are less prominent when banks are more inclined to search for higher income during periods of intense competition. Meanwhile, the risk profile of the financial institution does not modify the potency of the market competition-bond holding association. These results suggest that banks would retain more sovereign debt under competitive pressure for strategic rather than precautionary motives.
How Do the Political Connections and the Corporate Governance Mechanisms Affect the Firm Risk of Chinese Dual-listed Companies?
Authors: Wing Kwong Chan  , Ei Yet Chu
Published: December 2024

This research aims to assess the influences of political connections and corporate governance (CG) mechanisms on the firm risk of Chinese dual-listed companies (CDLC). CDLCs are Chinese companies that have core businesses in China and simultaneously list their shares in the Hong Kong and the China A-share markets. One hundred CDLCs are chosen for this research from 2003 to 2019. A binary variable of state control firm attribute (SCFA) is created to proxy the political connections to the Chinese government. The standard deviation of daily stock return and the mean of the natural logarithm of squared daily stock return are the two proxies of firm risk. The regression results show that the SCFA negatively influences the firm risk. Thus, the political connections, proxied by the SCFA, mitigate the firm risk. However, the state ownership’s influence on firm risk is insignificant. The regression results are supportive of our argument that SCFA and state ownership are two distinct concepts. Both the board size and independent director ratio insignificantly influence the firm risk. The CEO duality cannot be concluded to positively influences the firm risk and is not a destabilising factor in CDLCs. Evidence of the legal bonding effect is not observed in this research.
High-pressure single-crystal X-ray diffraction and Raman spectroscopy of boltwoodite, K0.63Na0.37[(UO2)(SiO3OH)](H2O)1.5
Authors: Chamberlain Carmen E. , Szymanowski Jennifer E.S. , Burns Peter C.
Published: December 2024

Uranyl silicates are common constituents of the oxidized portions of uranium ore deposits. Uranyl silicates are also known to form on used nuclear fuel pellets under simulated geologic repository conditions. These phases can incorporate a variety of cations, including higher actinides and fission products, which makes them relevant for studies that probe the stability of these phases in various contexts including irradiation, high temperatures, and high pressures.

The changes in the single-crystal structure and Raman spectroscopy of the uranyl silicate mineral boltwoodite, K0.63Na0.37[(UO2)(SiO3OH)](H2O)1.5, have been investigated at 11 pressures from ambient to 16.8 gigapascals (GPa). The bulk modulus was determined to be 26.3(4) GPa with a third-order Birch Murnaghan fit of the unit cell volume versus pressure. No obvious phase transition was observed between ambient pressure and 16.8 GPa. The structure is most easily compressed along the a-axis, which decreases by ca. 15% throughout the investigated pressure range, leading to distortions in the bonding geometries and higher coordination numbers of the interlayer cations. The b- and c-axes that are parallel to the uranyl silicate sheets are each compressed by ca. 4% compared to the ambient pressure structure by 16.8 GPa, which is attributed to the uranyl silicate sheets becoming more highly corrugated with increasing pressure.

Previous experimental high-pressure work with uranium(VI) phases is limited due to the complexity of refining heavy atom crystal structures with disordered cations and/or water molecules and the limitations imposed by the opening angle of the diamond anvil cell used to achieve high pressures. A method for overcoming these challenges is presented here to facilitate further high-pressure studies of heavy element minerals and other phases.
Nexus between green financial management and sustainable competitive advantage: Evidence from Indonesia
Authors: Nohong Mursalim , Sabir  , Try Dharsana Muhammad , Indra Hermansyah Fakhrul , Herman Bahtiar , Absah Yeni , Iqra Pradipta Natsir Andi
Published: December 2024

With increasing environmental and strategic challenges, achieving sustainable competitive advantage is crucial for businesses. This study aims to examine the impact of strategic risk and green financial management on sustainable competitive advantage, focusing on the mediating role of sustainable business resilience and the moderating effect of government policy. A quantitative approach was utilized, applying the SMART-PLS methodology to analyze data gathered through a survey of 316 small and medium-sized enterprise (SME) owners in Indonesia, selected for their direct involvement in daily operations and strategic decision-making. The response rate was 63.2%, representing various industry sectors. The results indicate that strategic risk significantly enhances sustainable business resilience (β = 0.796 and p-value < 0.01), which is strongly associated with sustainable competitive advantage (β = 0.458 and p-value < 0.01). Green financial management, however, does not significantly impact resilience (β = 0.008 and p-value = 0.89). Both strategic risk and green financial management, nonetheless, indirectly influence competitive advantage through resilience, reflecting partial mediation (β = 0.112, p-value = 0.02 and β = 0.053, p-value = 0.04, respectively). Additionally, government policy strengthens the effect of green financial management on resilience (β = 0.556 and p-value < 0.01). These findings underscore the importance of firms managing strategic risks proactively and providing supportive regulations to encourage sustainable business practices by governments. The study provides practical insights for businesses and policymakers aiming to foster corporate resilience and enhance sustainable competitive positioning.
VOSVIEWER İLE YERİNDE YAŞLANMA ÇALIŞMALARININ BİBLİYOMETRİK ANALİZİ: MEVCUT DURUM VE EĞİLİMLER
Authors: Pehlivan Neslihan Nur , Alayvaz Cansu
Published: December 2024

Yerinde yaşlanma, yaşlı bireylerin kendi evlerinde veya tanıdıkları çevrede bağımsız olarak yaşamlarını sürdürebilmelerini ifade eder. Son yıllarda yerinde yaşlanma konusunda yapılan araştırmalar hızla artmıştır. Bu çalışma, yerinde yaşlanma ile ilgili bilimsel araştırmaları inceleyerek, gelecekte bu alanda yapılacak araştırmalara yol gösterecek öncelikli konuları belirlemeyi amaçlamaktadır. Araştırma kapsamında, 1984-2024 yılları arasında Web of Science veri tabanında yerinde yaşlanma ile ilgili yayımlanmış 2937 çalışma bibliyometrik olarak analiz edilmiştir. Verilerin analizi, haritalaması ve ağ görselleştirmesi için VOSviewer yazılımı kullanılmıştır. Bu analizde bilimsel makaleler, yazarlar, ülkeler, kurumlar ve anahtar kelimeler gibi bilgiler değerlendirilmiş, sonuçlar ise VOSviewer adlı yazılım kullanılarak haritalama ve ağ görselleştirme teknikleri ile ortaya konmuştur. Yapılan analizde en çok makale (n= 2153) türünde yayın yer almaktadır. Analiz sonucunda, özellikle 2012 yılından sonra yayın sayısının belirgin bir şekilde arttığı görülmektedir. Bu konuda en çok yayın yapan araştırmacı Skubic, M. (n= 21) olurken, en aktif kurum Missouri Üniversitesi ve en fazla yayına sahip ülke ise ABD (n= 1118) olmuştur. Yerinde yaşlanmayla birlikte sıkça kullanılan anahtar kelimelerin “older adults (yaşlı yetişkinler)”, “aging (yaşlanma)”, “older people (yaşlı insanlar)”, “dementia (demans)”, “housing (konut)”, “technology (teknoloji)”, “elderly (yaşlı)” ve “long-term care (uzun süreli bakım)” olduğu görülmüştür. Çalışma, yerinde yaşlanma alanındaki araştırmacılara rehberlik ederek, gelecekteki iş birliği alanlarını belirlemekte ve araştırma eğilimlerini anlamaya katkı sağlamaktadır.
Penerapan Metode Big M dalam Pengoptimalan Hasil Produksi dan Analisis Sensitivitas (Studi Kasus: UMKM Rempeyek Ilham Jambi)
Authors: Ningsih Wahyu , Rozi Syamsyida , Multahadah Cut
Published: December 2024

In industrial businesses, a strategy for optimizing production results is an important thing to consider carefully so that the production process runs as efficiently as possible and the results obtained are feasible and optimal. This also needs to be a consideration for UMKM Rempeyek Ilham which are engaged in the production of peanut brittle. So, the aim of this research is to identify the number of optimal productions at UMKM Rempeyek Ilham so that maximum sales results can be obtained through modeling in the form of a linear program. However, the constraints formed in the linear programming model have sign of ≥, which cannot be resolved using the simplex method. One method that can be used to find a feasible and optimal solution for a linear programming model that has constraints ≥ is the Big M method. Therefore, in this research the Big M method is applied to find a feasible and optimal solution to the linear programming model. This research produces information about the number of optimal productions of peanut brittle with maximum sales of IDR 6,800,000.00. Furthermore, in this research a sensitivity analysis was also carried out to anticipate several possible changes that would occur so that the optimal solution obtained did not change or could even increase.Keywords: Big M method, Linear programming, Optimization, Sensitivity analysis.