bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural and functional properties of thrombomodulin
Authors: Bleskin D. A. , Koltsova E. M. , Nechipurenko D. Yu.
Published: July 2024

Thrombomodulin (TM) is an integral component of a multimolecular system, localized primarily in the vascular endothelium, and regulating a number of crucial physiological responses of an organism, including blood coagulation and inflammation. This review presents the currently known key functions of TM in the context of its structure. The first part of the review examines the domain structure of the TM molecule and describes the key molecular processes in which the corresponding domains participate. The second part of the review is devoted to a more detailed analysis of the TM molecule participation in the regulation of physiological processes in the human organism. Since the main function of TM is associated with the regulation of the hemostatic response to vascular wall injury, special attention is paid to the role of this molecule in the activation of protein C and thrombin-activated fibrinolysis inhibitor, which is responsible for stopping fibrinolysis. In addition, the review briefly describes some data on the role of TM in the mitogenesis of various cell types and in angiogenesis processes. One section of the review is devoted to the current knowledge of TM participation in the regulation of inflammatory reactions of the body. This section describes the key mechanisms through which TM is able to limit the level of pro-inflammatory signals, as well as regulate the processes of complement system activation.
A comparison of ex vivo and in vivo T-cell depletion for hematopoietic stem cell transplantation in children with malignant blood disorders
Authors: Vlasova A. A. , Vakhonina L. V. , Maisheva N. G. , Klevakin D. E. , Kostenko D. E. , Igumenshchev A. A. , Borovskikh S. V. , Verzhbitskaya T. Yu. , Ponomarev A. I. , Permikin Zh. V. , Tsaur G. A. , Fechina L. G.
Published: July 2024

A decrease in T cell alloreactivity following hematopoietic stem cell transplantation (HSCT) can be achieved via the depletion of TCRab+ and CD19+ lymphocytes or post-transplant therapy with high-dose cyclophosphamide (PTCy). The purpose of this study was to analyze HSCT outcomes according to the type of lymphocyte depletion. In our non-randomized retrospective study, we analyzed the results of 118 HSCTs performed in 107 patients with malignant blood disorders at the Center for Pediatric Oncology and Hematology of the Regional Children’s Clinical Hospital (Yekaterinburg) from 2010 to 2023. The patients were divided into 2 groups: those who had received ex vivo TCRab+/CD19+ depletion using the CliniMACS technology (n = 75; Group 1) and those who had received in vivo depletion using PTCy at a dose of 50 mg/kg (n = 43; Group 2). The study was approved by the Independent Ethics Committee and the Scientific Council of the Institute of Medical Cell Technologies (Yekaterinburg). Informed consent for the research and treatment was obtained from each patient and their legal representatives. Even though the patients from the TCRab+/CD19+ depletion group showed a better engraftment rate (median time: 12 days) than the subjects from the PTCy group (median time: 18 days) (p < 0.0001), there was no statistically significant difference in the cumulative incidence of cytomegalovirus and herpesvirus type 6 infection reactivation post-transplant between the two study groups. The cytomegalovirus reactivation rate was 0.467 and 0.466 in Group 1 and 2 respectively (p = 0.89), while for herpesvirus type 6 the reactivation rate was 0.360 and 0.240 respectively (p = 0.13). There were no significant differences in the cumulative incidence of acute graft-versus-host disease (GVHD) in the two groups by Day +100 (0.294 and 0.419 in Group 1 and 2 respectively; p = 0.77); neither was there any difference in the incidence of severe acute GVHD (0.067 and 0.093 respectively; p = 0.11). The incidence of chronic GVHD was 0.12 in the TCRab+/CD19+ depletion group and 0.26 in the PTCy group (p = 0.11). The event-free survival, overall survival and cumulative incidence of relapse did not differ between the studied groups either. The two methods of the depletion of unwanted T-cell populations showed a comparable effectiveness. The choice between them should be based on factors related to the biological characteristics of the disease and the clinical status of a patient. The availability of different depletion methods at a single transplant center helps to choose the optimal treatment option for patients who are in need of HSCT.
Desenvolvimento regional e saúde: a importância da extensão universitária na saúde visual na Amplanorte
Authors: Haensch Suellen Cristine , Gumbowsky Argos , Walczak Lisandro , Guimarães Marcio Bonatto
Published: July 2024

As universidades desempenham um papel fundamental no desenvolvimento regional por meio de suas atividades de ensino, pesquisa e extensão. Este artigo teve como objetivo examinar a relação entre a extensão universitária da Clínica de Saúde Visual da Universidade do Contestado e o desenvolvimento regional, de acordo com gestores de educação e saúde da Amplanorte. A pesquisa foi classificada como descritiva e exploratória, com métodos de coleta de dados bibliográficos e de campo, e uma abordagem qualitativa e quantitativa. A coleta de dados foi realizada através de formulários online respondidos por secretários municipais de educação, diretores escolares e secretários municipais de saúde, totalizando 24 participantes. Os resultados indicaram uma percepção positiva predominante entre os participantes, sugerindo que a Clínica de Saúde Visual contribuiu para o desenvolvimento humano e sustentável da população da Amplanorte. 
Palavras-chave: Saúde visual; extensão universitária; optometria; desenvolvimento regional.
Crowd noise spectra for the calculation of the speech transmission index for public address systems
Authors: Dziechciński Paweł
Published: July 2024

Knowledge of interfering noise is necessary for the correct design of a public address system. Noise sound levels can be obtained, for example, from BS 5389-1. It is more difficult to acquire knowledge of the interfering noise spectra, and the spectrum is also important for calculating speech intelligibility. As shown in the paper, for crowd noise, it is possible to determine the spectrum by pairing the level of noise to the speech spectrum for appropriate vocal effort. The error in determining the speech transmission index for public address systems for such selected noise spectra, relative to values for measurement-acquired noise spectra, is acceptable.
Origin and properties of own error signals of the discrete wavelet transform algorithms
Authors: Dróżdż Łukasz , Roj Jerzy
Published: July 2024

The article presents a method for analyzing the own errors of the discrete wavelet transform algorithms, which are introduced by these algorithms into the output quantities. The presented considerations include determining the origin of the error signals in question and determining their parameters. Both errors resulting from imperfections in the transmittance of the algorithm and those resulting from its implementation in the actual measurement chain were considered.
Predictive Analysis on the Influence of Al2O3 and CuO Nanoparticles on the Thermal Conductivity of R1234yf-Based Refrigerants
Authors: Bibin Baiju S. , Bhramara Panitapu , Mystkowski Arkadiusz , Gundabattini Edison
Published: July 2024

Nano-enhanced refrigerants are substances in which the nanoparticles are suspended in the refrigerant at the desired concentration. They have the potential to improve the performance of refrigeration and air-conditioning systems that use vapour compression. This study focuses on the thermal conductivity of alumina (Al2O3) and cupric oxide (CuO) nanoparticles immersed in 2,3,3,3-tetrafluoropropene (R1234yf). The thermal conductivity of nano-refrigerants was investigated using appropriate models from earlier studies where the volume concentration of particles and temperatures were varied from 1% to 5% and from 273 K to 323K, respectively. The acquired results are supported by prior experimental investigations on R134a-based nano-refrigerants undertaken by the researchers. The main investigation results indicate that the thermal conductivity of Al2O3/R1234yf and CuO/R1234yf is enhanced with the particle concentrations, interfacial layer thickness, and temperature. Also, the thermal conductivity of Al2O3/R1234yf and CuO/R1234yf decreases with particle size. The thermal conductivity of Al2O3/R1234yf and CuO/R1234yf nano-refrigerants become enhanced with a volume concentration of nano-sized particles by 41.2% and 148.1% respectively at 5% volume concentration and 323K temperature. The thermal conductivity of Al2O3/R1234yf reduces with temperature, by upto 3% of nanoparticle addition and after that, it enhances. Meanwhile, it declines with temperature, by upto 1% of CuO nanoparticle inclusion for CuO/R1234yf. CuO/R1234yf has a thermal conductivity of 16.69% greater than Al2O3/R1234yf at a 5% volume concentration. This paper also concludes that, among the models for thermal conductivity study, Stiprasert’s model is the most accurate and advanced.
Identifying multidisciplinary problems from scientific publications based on a text generation method
Authors: Xu Ziyan , Han Hongqi , Li Linna , Zhang Junsheng , Zhou Zexu
Published: July 2024

Purpose

A text generation based multidisciplinary problem identification method is proposed, which does not rely on a large amount of data annotation.

Design/methodology/approach

The proposed method first identifies the research objective types and disciplinary labels of papers using a text classification technique; second, it generates abstractive titles for each paper based on abstract and research objective types using a generative pre-trained language model; third, it extracts problem phrases from generated titles according to regular expression rules; fourth, it creates problem relation networks and identifies the same problems by exploiting a weighted community detection algorithm; finally, it identifies multidisciplinary problems based on the disciplinary labels of papers.

Findings

Experiments in the “Carbon Peaking and Carbon Neutrality” field show that the proposed method can effectively identify multidisciplinary research problems. The disciplinary distribution of the identified problems is consistent with our understanding of multidisciplinary collaboration in the field.

Research limitations

It is necessary to use the proposed method in other multidisciplinary fields to validate its effectiveness.

Practical implications

Multidisciplinary problem identification helps to gather multidisciplinary forces to solve complex real-world problems for the governments, fund valuable multidisciplinary problems for research management authorities, and borrow ideas from other disciplines for researchers.

Originality/value

This approach proposes a novel multidisciplinary problem identification method based on text generation, which identifies multidisciplinary problems based on generative abstractive titles of papers without data annotation required by standard sequence labeling techniques.
The Relationship Between Dialogue Forms and Verbs of Non-Speech in Russian and Japanese Novels
Authors: Kitajo Mitsushi
Published: July 2024

In literary works, the dialogue is expressed by direct speech construction. The direct speech construction consists of author’s words (AW) and character’s words (CW). The predicate verbs of AW in the dialogue form include not only verbs indicating speech (TVS) but also verbs that do not denote speech (TVN). The dialogue forms are divided into four types according to the positional combinations of AW and CW. Type A: AW is in preposition to CW; Type B: AW is in postposition to CW; Type C: AW is in interposition to CW; Type D: AW includes CW. Previous studies have not paid sufficient attention to the relationship between TVN and the dialogue forms. This paper proposes two analysis criteria: 1) frequency of the 4 types indicated above and frequency of TVN, 2) frequency of the 4 types and frequency of TVN depending on semantics. Here, we study the material selected from Russian novels and Japanese novels of the second half of the 19th – second half of the 20th century. Our analysis has revealed the following: 1) in Russian novels, TVN appears intensively in type C, while in Japanese novels TVN does not appear disproportionately in a specific type of the dialogue form while the use of TVN depends on the most frequently used dialogue form. 2) TVNs meaning ‘facial expression’ and ‘gesture’ are frequently used in all dialogue forms in Russian and Japanese novels. Theoretically, TVN and type C are closely related, but it seems that TVN appears differently in type C due to the difference in recognition of type C between Russian and Japanese.
Enhancing Registers and Styles: Grammatical Dimension
Authors: Vovk Olena , Pashis Larysa
Published: July 2024

This study explores the issue of acquiring stylistic grammar by University students – teacher-trainees. The results of the observation made it possible to arrive at the conclusion about the expedience of teaching stylistic grammar to junior students of language schools, but with different levels of stylistic loading. With this in mind, a corresponding methodology is designed, which incorporates a system of stylistically oriented activities. They embrace non-communicative receptive, quasi-communicative receptive-reproductive and communicative productive exercises to be employed in the English classroom. It is maintained that the employment of the proposed system of activities begins in the junior years and continues through the University course in order to obtain expected learning outcomes.
Evaluation and management of antrochoanal polyps in children
Authors: Iovanescu Gheorghe , Anglitoiu Alina Elisabeta , Marin Karina Cristina , Gidea Dana Florentina , Iovanescu Dan , Vintila Roxana Daniela
Published: July 2024

BACKGROUND. Antrochoanal polyps (ACP) were originally reported by Gustav Killian in 1906. Antrochoanal polyps (ACPs) are benign polypoid lesions that begin in the maxillary antrum and extend into the choana. Although there have been recorded occurrences of bilateral ACPs in the literature, ACPs are mostly unilateral. They typically have an impact on youth and youngsters.

MATERIAL AND METHODS. In a trial of 15 cases treated and admitted to our ENT Pediatric Department at the Emergency County Hospital Timisoara over the previous four years, the pathology, differential diagnosis, treatment, complications, etiopathogenesis, clinical features, positive and differential diagnosis, preoperative evaluation, pathology, and treatment of ACPs were reviewed in this study.

RESULTS. The patients age group comprised five females (33.33%) and ten boys (66.67%), ranging in age from 7 to 16 years. The most common presenting symptoms were unilateral nasal obstruction (100%), purulent rhinorrhea (66.67%), olfactory impairment (53.33%), and mouth breathing (46.67%). A nasal endoscopy and a craniofacial CT scan were the gold standards for diagnosing ACP. The chosen course of treatment for all pediatric patients included in the study was surgery: 12 patients (80%) underwent transnasal endoscopic polypectomy, and 3 patients (20%) underwent both transnasal polypectomy and transcanine fossa approach. The success rate of the combined endoscopic and transcanine fossa approach was 100%, whereas the transnasal endoscopic surgery (polypectomy) had an 80% success rate.

CONCLUSION. Polypectomy combined with a transcanine fossa approach technique and transnasal polypectomy is the optimal course of treatment.
Optimalisasi Investasi Asing Langsung dan Keterbukaan Ekonomi terhadap Nilai Tukar Efektif Riil di Indonesia
Authors: Shahmi Mohammad Aliman , Irawan Rinaldi , Nengsi Tamara Suria , Fauziah Yunadia , Abdullah Stevan , Oktafannisa Salsabilla
Published: July 2024

Penelitian ini bertujuan untuk menganalisis pengaruh dan keseimbangan investasi asing langsung, ketebukaan ekonomi, stabilitas harga dan neraca transaksi berjalan di Indonesia dalam jangka panjang dan jangka pendek di Indonesia dari tahun 1993-2022. Penelitian ini sepenuhnya menggunakan data sekunder yang dikumpulkan dari World bank dan Fred Economics data. Penelitian ini menggunakan pendekatan error correction model (ECM). Hasil penelitian ini menujukkan bahwa investasi asing langsung, keterbukaan ekonomi dan Tingkat harga berpengaruh signifikan terhadap real effective exchange rate di Indonesia dalam jangka panjang. Sementara itu, Neraca transaksi berjalan tidak berpengaruh signifikan terhadap nilai tukar efektif riil. Dalam jangka pendek, Keterbukaan ekonomi dan investasi asing langsung berpengaruh signfikan terhadap nilai tukar efektif riil di Indonesia, sementara itu Tingkat harga dan neraca transaksi berjalan tidak berpengaruh signifikan terhadap nilai tukar efektif riil di Indonesia. Perubahan pada Tingkat harga dan neraca transaksi berjalan menjadi pengganggu keseimbangan nilai tukar efektif riil dalam jangka pendek. Namun,Tingkat harga melakukan penyesuaian dalam janga panjang. Sementara itu, keterbukaan ekonomi dan investasi asing lansung menunjukkan pengaruh optimal terhadap perubahan nilai tukar efektif riil di Indonesia.
The Material and Energy Conversion Potential from Municipal Waste in Padang City: Business Chance and Future Prospective
Authors: Putra Alqadri Asri , Rasyidin Azwar
Published: July 2024

Padang City, the capital city of West Sumatra Province, is expected to grow and reach a population of 1 million by 2035. However, this growth also means an increase in municipal solid waste, projected to be about 256,000 tons annually. At the same time, there is potential for waste-to-energy conversion in Padang City due to the demand for renewable energy and business opportunities. This study is based on existing literature and data, which were analyzed using a statistical approach and municipal solid waste management calculations. The study conducted scenarios that show potential energy conversions. The first scenario involves converting solid waste to gas and using it directly as biogas. The second scenario involves converting biogas from solid waste to electricity and distributing it for household use. The last scenario consists of using small and medium-sized biodigesters to convert gas into electricity, which will then be used as a charging station for electric vehicles (EVs). The first scenario can generate the most significant profit, while the third scenario suits small and medium businesses. However, each scenario has its pros and cons. Still, it's crucial to consider regulation issues, government support, and public awareness of the environmental problems to implement these waste-to-energy conversion practices on-site successfully.
Dicephalus Parapagus Conjoined Twins
Authors: Febrianda Alfa , Roza Sriyanti
Published: July 2024

Background: Conjoined twins are monoamniotic monochorionic twins resulting from incomplete division of the embryonic disk and amniotic sac. This rare condition has an incidence of 1:33,000 to 1:165,000 pregnancies. Common types include thoracopagus and omphalopagus, with less common forms like thoracoomphalopagus, pyopagus, ischiopagus, and craniopagus. Parapagus, where twins are joined at the sides with a shared pelvis and organs, occurs in less than 0.5% of cases.
Case: A 27-year-old patient presented to the Fetomaternal Clinic at RSUP M. Djamil Padang, referred from Hermina Hospital, with a diagnosis of G2P1A0H1 gravid preterm and suspected conjoined twins. Ultrasound at 5 months showed two heads and one body. Initial assessment noted a family history of twins and palpable round, firm masses. Laboratory tests, Fetomaternal ultrasound, MRI, and 3D CT Scan confirmed conjoined twins (dicephalus, parapagus, dibrachius). A cesarean section was planned.
Discussion: Termination involves a multidisciplinary team to manage fetal anatomical abnormalities optimally. Emergency separation has a 70% mortality rate, higher than the 20% for elective procedures. Treatment depends on cardiovascular anatomy, with higher success if only the pericardium is divided. Cardiac anomalies' severity influences prognosis, survival, and separation feasibility. Survival rates depend on the degree of union and cardiac anomalies. In cases like dicephalus, the anatomical structure often makes it unlikely for both twins to survive separation.
“Theologising the Bounds of Community: VOC Religious Policies in the Early Cape Colony”
Authors: Spurlock Scott
Published: July 2024

This paper seeks to challenge scholarly assumptions over the role that Reformed religion played in the first 50 years of the Cape colony. Rather than rooted in a doctrine of external holiness, it is argued the practice of baptism reflected a covenantal framework that served as a theological basis for ordering and demarcating an increasingly diversified community while maintaining strict social hierarchies. In so doing, the VOC created a community defined by covenantal inclusion and exclusion. While this radically changed over time, the early policy should be understood in its context.
The Life and Work of the Presbyterian Church of Southern Africa: The Doctrinal Dimension of Baptism
Authors: Duncan Graham
Published: July 2024

A perduring theological and practical problem of the universal church relates to the doctrine of baptism. This article investigates hermeneutical and historical issues in relation to what it means to be a member of Christ’s church and the implications thereof in the specific context of the Presbyterian Church of Southern Africa (PCSA). The debate has arisen in relation to the options of infant and believer’s baptism, or believer’s baptism. Within Christian denominations there are often conflicts regarding exclusive and inclusive policies. While the PCSA followed the main trend of the sixteenth century Reformation churches, there is disagreement among some of its members on various points. The article is based primarily on a literature review of primary sources. It is structured in terms of its origin, history, and external influences, namely: the charismatic renewal; the sacrament of Holy Communion and rebaptism; the covenant and baptism; and the South African context.
Risk Factors Associated with Hopelessness among Unemployed Graduates during the Covid-19 Lockdown in South Africa
Authors: Thakoordeen-Reddy Semone , Sewpaul Ronel , Ramlagan Shandir , Dukhi Natisha , Shean Yolande , Sifunda Sibusiso
Published: July 2024

Hopelessness is defined as having a pessimistic expectation of the future and the belief that goals are unachievable. It is reported to be high among the unemployed. During the Covid-19 pandemic, unemployment increased, especially among young graduates. Hence, in this study, we aimed to find the factors that contributed to developing feelings of hopelessness in unemployed South African graduates. This study made use of the survey data obtained from the larger Presidential Youth Employment Initiative (PYEI) study. The primary outcome variable was the presence of hopelessness, which was based on Beck’s Hopelessness Scale (BHS). The study participants completed a self-administered questionnaire on a data-free online platform within two months of commencement of employment in the PYEI internship programme. The survey data were analysed using Stata 15.0. (StataCorp Texas USA 2016). The prevalence of hopelessness was presented by the independent variables of interest. Bivariate logistic regression models were used to investigate the association between the independent variables with the primary outcome of hopelessness. Our study reported that being “not African” was associated with hopelessness and that prolonged social media use protected against developing feelings of hopelessness. Identifying these risk factors is vital in caring for the mental health of South Africans.
The Pertinence of Library and Information Science in Promoting Sustainable Development
Authors: Odularo Oluwayemi
Published: July 2024

Library and Information Science (LIS) plays a vital role in promoting Sustainable Development Goals (SDGs). This paper examines the research gap on the challenges of LIS concerning the need to promote SDGs. We examine challenges, such as inadequate research on the specific impact of libraries on sustainable development, particularly in varying socioeconomic settings, and limited research on the obstacles that impede libraries from effectively carrying out sustainable initiatives, such as inadequate funding and institutional obstacles. The methodology adopted in the study is the Systematic Literature Review (SLR), which entails the inclusion and exclusion research design. The Information Behaviour Theory was adopted to seek an understanding of how people seek, use and share information. The role of libraries is critical for sustainable development. The article also examines the barriers facing LIS in promoting sustainable development. The findings reveal that libraries are unique in providing access to information and resources, offering educational programmes and events, implementing sustainable practices, and collaborating with other organisations to promote sustainability and contribute to the SDGs. The article recommends that libraries, as public and private sector entities, must collaborate to deliver greater dividends of the SDGs. The study also advocates for further studies regarding the long-term impact of library programmes on SDGs’ achievement.
Cohabiting Relationships as Matula for Young Women and Grounds for Intimate Partner Violence: A Critical Feminist Perspective
Authors: Makongoza Matamela , Peace Kiguwa  , Simangele Mayisela
Published: July 2024

In this article, we critically reflect on the literature on intimate partner violence and the importance of an African feminist lens to understanding the influence of cultural discourse and practice in cohabitating relationships. We focus on intimate partner violence experienced by black young women in cohabiting relationships among the Vhavenda cultural group in South Africa. We reflect on the concept of matula, which views and constructs cohabitation as a taboo practice. We ask: what does it mean to intervene and respond to incidences of intimate violence in a relationship that is already socially and culturally negated? We interrogate the relevance of African feminist epistemology that prioritises cultural beliefs, customs, traditions, values and behaviour. Such epistemology, we argue, reflects the importance of thinking of gender and gender-based violence in the context of culture as dynamic and constantly negotiated by community members. Lastly, we explore the relevance of the African feminist perspective as part of the work of disrupting essentialising cultural and traditional practices that function to entrench gendered power dynamics. This study is conceptualised from a qualitative approach with in-depth, unstructured one-on-one interviews. Ten interviews with young women between the ages of 18 and 24 years were conducted through the Thohoyandou Victim Empowerment Programme in the Vhembe District, South Africa.
Barriers to and Facilitators of Treatment Adherence Among Caregivers of Children with Atopic Dermatitis: Exploring the Role of Attachment
Authors: Field Courtney , Lachman Anusha , Shongwe Lindokuhle , Roomaney Rizwana
Published: July 2024

Atopic dermatitis (AD) or eczema is an inflammatory skin disease, usually with an onset in early childhood. The primary symptoms and signs of AD are itchy, dry, flaky skin and lichenification (thickening of the skin), which can cause severe discomfort, pain and irritation. Treatment consists of medication and specialised therapies. As children usually do not have the capacity to manage the condition themselves, the onus falls on the caregiver to provide the appropriate treatment. Caregivers are required to carefully monitor skin triggers, administer creams, and maintain diligent observation of the child. The attachment relationship between a child and caregiver may be an influential factor in treatment. In this qualitative study, we explored the barriers to and facilitators of treatment adherence for caregivers with children under the age of 12 years with AD. Twenty AD caregivers were purposively recruited at a specialist dermatology clinic at a tertiary hospital in the Western Cape, South Africa. Interviews were conducted, recorded, transcribed and analysed using thematic analysis. The participants reported that inadequate primary healthcare, the costs associated with treatment and the lack of resources at schools were barriers to treatment adherence. They also stated that specialised healthcare, their use of innovative treatment methods, responsive care and social support facilitated treatment adherence. We add that attachment may play an important role in the provision of treatment from caregivers and that innovative treatment and responsive care by caregivers specifically demonstrate how secure attachments enable caregivers to be responsive to the needs of the child patient.
Panorama atual dos fatores de interferência na amamentação exclusiva
Authors: Hanna Leila Maués Oliveira , Prestes Ananda Carolina Reis , Diogo Leonardo Rodrigues Ferreira , Naimayer Kallaiho Kevin Dantas , Martins Léo Vitor Araújo , Rodrigues Tales Roberto Figueiredo Amorim
Published: July 2024

Objetivo: Identificar os fatores de interferência na amamentação exclusiva e as medidas que possam amenizar a problemática no âmbito social e fisiológico, em uma escala de saúde pública. Métodos: Trata-se de uma revisão de literatura observacional, qualitativa e transversal. A pesquisa foi realizada nas bases PubMed e Biblioteca Virtual em Saúde (BVS), por meio dos descritores “breast feeding” e “prenatal education” e “milk, human”. A elegibilidade dos artigos corresponderá aqueles que façam parte da temática. Serão descartados estudos fora do período de 2019 a 2023, assim como revisões de literatura. Resultados: Foram selecionadas 11 publicações, as quais destacaram a ausência de informações no pré-natal, condições socioeconômicas, influência familiar, saúde mental e insegurança materna como os principais fatores que podem interferir no AME. Considerações finais: Portanto, a deficiência de orientações quanto ao AME, fatores psicológicos maternos, socioeconômicos e o uso de substâncias influenciam na diminuição do aleitamento materno, o que gera consequências para a mãe e para filho. Isso pode ser solucionado ao desmistificar crenças sobre a amamentação, apresentar informações positivas além de identificar os direitos e deveres maternos.
Can the Internal Nasal Valves Method Be a Game Changer for Preventing Respiratory Tract Infections?
Authors: Varma Ashok B.
Published: July 2024

An anaphylactic reaction to the influenza vaccine prompted a search for a non-pharmacological way to prevent respiratory tract infections (RTIs) using the internal nasal valves and the innate immune system. The anatomy and physics of the internal nasal valves, using Bernoulli’s principle, can produce a Venturi effect and suction out the pathogen-laden secretions of the nasal cavities, sinuses, nasolacrimal ducts, and Eustachian tubes. The very effective innate immune system could then neutralize these pathogens.

This self-experimentation describes The Internal Nasal Valves (INVals) Method developed by the author for RTIs’ prevention in 1979 and its regular practice since with full compliance and discipline. The coronavirus disease 2019 (COVID-19) pandemic provided him with an opportunity for self-experimentation to perform a trial of The INVals Method on himself despite his age of 73 years and the possibility of highly adverse outcomes.

The author observed, enjoyed, and was impressed with the benefits of The INVals Method during the peak of the COVID-19 pandemic. As of this writing, he has not suffered from any RTIs since using The INVals Method in 1979.

The author’s experiment is a real-world experiment and suggests that The INVals Method may help prevent RTIs and be an ally and complement to the vaccines. Further investigations to test, retest, and test more of the author’s experiment with rigorous randomized controlled trials (RCTs)/cohort RCTs/cluster randomized trials are warranted to support his results. If future research proves that the author’s results are correct and meaningful, it may have a broader clinical impact across medicine as an ally of vaccines, especially in the developing countries where there can be lag period in acquisition and administration of vaccines.
COMPREHENSIVE APPROACH TO FEASIBILITY ANALYSIS OF NEW CONSTRUCTION MATERIALS
Authors: Иноземцев С.С. , Иноземцев А.С. , Королев Е.В.
Published: July 2024

Новые технические и технологические решения, обоснование эффективности которых основывается только на экономических критериях, с развитием науки и техники становятся недостаточными. Это требует разработки технологических подходов, результаты которых дают продукции технические преимущества, обеспечивающие достижение экономической эффективности их применения. Рациональным подходом, позволяющим комплексно оценить эффективность применения композиционных материалов, является использование методов системного анализа метода комплексных технико-экономических показателей. В статье предложен подход для обоснования технико-экономической эффективности технологии, заключающийся в оценке стоимости нового технологического решения, позволяющего повысить качество материала. Условием, при котором вариант технологического решения признается эффективным по установленному критерию качества (обобщенный критерий качества), является достижение максимального значения коэффициента эффективности. Представленный подход технико-экономического обоснования внедрения строи-тельных материалов, выполненный на примере высокопрочного легкого фибробетона, показывает возможность комплексной оценки целесообразности использования новых технологических решений. С помощью критериального метода показано, что технология высокопрочного легкого бетона, обладающего уникальным набором свойств, отличается лучшей технико-экономической эффективностью на 2439 по сравнению с базовой технологией тяжелого высокопрочного бетона.

Science and technology, new technical and technological solutions are rapidly developing. However, the rationale for the effectiveness is still based only on economic criteria. Therefore, it is necessary to develop the universal approaches to the assessment of economic efficiency of technological solutions. A rational approach to the complex assessment of the effectiveness ofthe use of composite materials is the use of system analysis methods the method of complex technical and economic indicators. The authors propose a feasibility approach in order to justify the effectiveness of technology, which assesses the cost of a new technological solution aimed at improving the quality of the material. The technological solution according to this approach is recognized as effective according to the established quality criterion (generalized quality criterion) if the maximum value of the efficiency coefficient is achieved. The presented approach, tested on high-strength lightweight fiber-reinforced concrete, shows the possibility of a comprehensive assessment of the feasibility of using new technological solutions. Using the criteria method, it has been shown that the technology of high-strength lightweight concrete with a unique set of properties has the best technical and economic efficiency of 24...39 as compared with the conventional technology of heavy high-strength concrete.
Near Infra-Red Irradiation for Warming-up Mechanosynthesis
Authors: Tanepau Joao , Bonnaanaa Hafsa , Macé Angèle , Guérin Arthur , Lenormand Philibert , Lamaty Frédéric , Pinaud Julien , Bantreil Xavier
Published: July 2024

Albeit mechanochemistry is a novel promising technology that give access to reactivity under solvent-free conditions, heating such reactions is sometimes compulsory to obtain satisfactory results in terms of conversion, selectivity and/or yield. In this work, we developed a novel approach using a dye that absorbs NIR photons and release the energy as heat. Hence, milling jars in epoxy resin doped with the dye were thus produced to obtain reactors that would produce heat upon irradiation at 850 nm. Temperature profiles were recorded, depending on the irradiance, dye charge in the resin, and milling frequency, showing an excellent control of the temperature. The usefulness of the heating jar was then demonstrated in mechanochemical reactions that are known to require heat to yield the desired product, namely Diels-Alder reactions with high activation energies and the newly developed rearrangement of a sydnone into corresponding 1,3,4- oxadiazolin-2-one.
How Hot Plasmonic Heating Can Be: Phase Transition and Melting of P25 TiO2 from Plasmonic Heating of Au Nanoparticles
Authors: Lu Weigang , Kayastha Rohil , Birmingham Blake , Zechmann Bernd , Zhang Zhenrong
Published: July 2024

Plasmonic heating has been utilized in many applications, including photocatalysis, photothermal therapy, and photocuring. However, the heat dissipation process of the plasmonic nanoparticles (NPs) and the surrounding matrix is complex. How high the temperature of the matrix that surrounds the plasmonic NPs, such as the catalyst and substrate, can be reached is unclear. Herein, we study the dissipation of plasmonic heat generated by resonantly excited gold (Au) NPs dispersed on P25 TiO2 NP porous film in air. Under resonant 532 nm continuous wave (CW) laser irradiation at the surface of the Au-TiO2, the surface evaporation and the aggregation of Au NPs were observed at moderate laser power (10 mW/um2). This process is accompanied by the phase transition of TiO2. More importantly, the TiO2 nanoparticle film melted, forming melt pools and molten TiO2 matrix. This indicates that the temperature of the TiO2 reached as high as its melting point of 1830 °C. When Au/TiO2 was irradiated with an off-resonance laser at 638 nm, no phase transformation or melting of TiO2 was observed. The temperature calculation showed that the heating generated by Au NPs is not localized. The collective heating from an ensemble of Au NPs in the irradiated area produced a global temperature rise that melted TiO2. Our results suggest that the photothermal effect could be a significant mechanism in the plasmon-assisted photocatalytic reactions. The melting of the supporting metal oxide film by plasmonic heating at relatively low laser power suggests new applications for utilizing plasmonic heating, such as additive manufacturing.
Synthesis of Aryl-fused Bicyclo[3.1.1]heptanes (BCHeps) and Validation as Naphthyl Bioisosteres
Authors: Kerckhoffs Aidan , Tregear Maud , Hernandez-Llado Pol , Runfola Massimiliano , Shearsmith Holly , Frank Nils , Squire Sarah , Moir Lee , Christensen Kirsten , Duarte Fernanda , Davies Kay , Russell Angela
Published: July 2024

While naphthalene rings are often encountered in drugs, candidates and lead molecules, they can be susceptible to cy-tochrome P450-mediated metabolism in biological systems and exhibit flat, sp2-rich structures, limiting their utility in drug-like candidates. Herein, we report the first library of derivatisable aryl-fused Bicyclo[3.1.1]heptanes (BCHeps) as bioisosteric replacements for (β-)naphthalene and other fused bicyclic aromatics. We incorporate the BCHep-based naphthyl isosteres into the AhR antagonist ezutromid and observe geometrically similar exit vectors while reducing Fsp2, and retainment of biological activity while improving metabolic stability towards CYP metabolism, validating these motifs as ‘true’ bioisosteric replacements for meta-substituted arenes and 2-naphthalenes.
Data Loss Transmission in 5g Network by Enabling Green Blockchain Methodologies
Authors: S. Thiruvenkatasamy  , G. Devi  , B. Gayathri  , C. KaviyaSri  , E. Leela
Published: July 2024

Network embedding successfully maintains the network structure by assigning network nodes to low-dimensional representations. A considerable amount of progress has recently been achieved in the direction of this new paradigm for network research. In this study, we concentrate on classifying, analyzing, and pointing out the future direction for network embedding techniques to research. We begin by summarizing the purpose of network embedding. We talk about network embedding and how it relates to traditional graph embedding methods in a cognitive radio context. Following that, we give a thorough overview of the network embedding techniques methodical way, including advanced information-preserving network embedding techniques, network embedding techniques with side information, and approaches that preserve structure and properties. Additionally, many methods of network embedding assessment and some practical online tools, such as network data sets and software, are explored. In the last section, we cover the foundation for utilizing these network embedding techniques to create a successful system and identify possible future paths.
Comparing Factors Influencing Loyal Consumption Behavior Towards Fast-Food Restaurants
Authors: Obulesu Varikunta  , Kethavath Sachin
Published: July 2024

The purpose of this paper is to investigate the factors influencing the satisfaction of customer and customer loyalty in the fast food restaurant industry. A theoretical model, including hypotheses, has been proposed in this study. Data were assembled using convenient sampling method. The hypothesized model was verified with the data from 204 respondents. Principal component analysis and structural equation modeling approach were applied to analyze data. The results (significant at po0.01 and po0.05) exhibited that food quality, price and service qualities were positively linked to customer satisfaction. Customer satisfaction was positively associated with customer loyalty. The empirical results found a contrary association between the location and environment of restaurant and customer satisfaction. Customer loyalty studies generally indicate that fast-food customers are not genuinely loyal to brands or products mainly because they function under low-switching cost conditions. The purpose of this research is to empirically study whether fast-food customers genuinely become loyal and, if so, how. The study adopts the theory and method of the satisfaction-trust-commitment-loyalty explanation chain and examines the consumer survey results obtained under conditions of low-switching costs. Analyses of the results indicate that the proposed relationships provide appropriate explanatory power for the phenomenon at hand and that fast- food customers truly become loyal despite conditions of low switching costs. The findings and the research and practical implications are thoroughly discussed.
Managing Emotions in Ongoing Service Relationships: New Intrinsic and Extrinsic Emotion Regulation Strategies
Authors: Nattala Vanaja  , Sahithi Gatla
Published: July 2024

The purpose of this paper is to investigate the factors influencing the satisfaction of customer and customer loyalty in the fast food restaurant industry. A theoretical model, including hypotheses, has been proposed in this study. Data were assembled using convenient sampling method. The hypothesized model was verified with the data from 204 respondents. Principal component analysis and structural equation modeling approach were applied to analyze data. The results (significant at po0.01 and po0.05) exhibited that food quality, price and service qualities were positively linked to customer satisfaction. Customer satisfaction was positively associated with customer loyalty. The empirical results found a contrary association between the location and environment of restaurant and customer satisfaction. Customer loyalty studies generally indicate that fast-food customers are not genuinely loyal to brands or products mainly because they function under low-switching cost conditions. The purpose of this research is to empirically study whether fast-food customers genuinely become loyal and, if so, how. The study adopts the theory and method of the satisfaction-trust-commitment-loyalty explanation chain and examines the consumer survey results obtained under conditions of low-switching costs. Analyses of the results indicate that the proposed relationships provide appropriate explanatory power for the phenomenon at hand and that fast- food customers truly become loyal despite conditions of low switching costs. The findings and the research and practical implications are thoroughly discussed.
Ensinando Teoria da Comunicação em um curso de Letras: esboço de uma leitura de micro-história de um livro-texto de 1985
Authors: Martino Luis Mauro Sá
Published: July 2024

Este artigo examina um livro-texto de Teoria da Comunicação, de circulação restrita, voltado para estudantes de Letras da Universidade Estadual Paulista Campus de Assis (Unesp/Assis), Introdução à Teoria da Comunicação, de Rafael Eugenio Hoyos-Andrade (1985). Delineiam-se aspectos dos significados atribuídos à disciplina, bem como seus conceitos centrais, na ótica de uma outra área. A partir de uma leitura que toma de empréstimo conceitos da micro-história, observa-se que (1) o livro oferece uma ampla gama de conceitos de comunicação, indicando a ausência de consenso sobre o tema; (2) apesar disso, foca principalmente nos meios de comunicação de massa e na teoria da informação (também descrita como “semiologia”); (3) a bibliografia se pauta em títulos de várias disciplinas, da sociologia à linguística e à semiótica. Esses pontos são tratados em suas intersecções com problemas epistemológicos contemporâneos da Comunicação.
O jornal O Mossoroense e o definhamento do sistema de valores da ditadura civil-militar brasileira no processo de abertura (1970-1983)
Authors: Nascimento Suliendson Dantas do , Bonsanto André
Published: July 2024

Tomando como referência teórico-metodológica Michel Foucault e Michel de Certeau para pensar a arqueologia em sua condição de análise qualitativa do discurso, demonstra-se neste artigo como o jornal da cidade de Mossoró -RN, O Mossoroense, na tentativa de dialogar com seu público, capturou materialidades discursivas do processo de abertura política durante o período da ditadura civil-militar (1970-1983). Envolto pelas tensões das polarizações sócio-históricas que vivia o Brasil no início da década de 1970, o cenário político da região do Oeste Potiguar passava também por uma dinâmica paradoxal de exaltação, depreciação e descrédito do sistema de enunciados que conduziram o regime ao seu lento fim, fazendo emergir e circular os primeiros enunciados que dariam suporte ao processo de redemocratização do país.
EDUCATIONAL PROGRAMS FOR INITIAL TEACHER TRAINING IN PLAYFUL PEDAGOGY
Authors: PIELE Andrada-Narcisa , SAVA Simona Lidia
Published: July 2024

The use of games or playful activities in the educational process has recently attracted the interest of researchers, who aim to include them as specific ways of teaching, learning, and assessment, in order to make learning more engaging and impactful. The benefits of game-based instructional interactions have been shown by several studies and promoted by UNICEF and the Lego Foundation. Learning through play or playful learning is essential in quality education. Numerous studies have highlighted the need to include playful pedagogy in initial teacher education and this article systematically analyzes those that are published between 2014-2024 and are included in Scopus. A total of 20 articles met the inclusion criteria that aimed to identify the characteristics of effective teacher training programs in promoting playful pedagogy, while arguing the need for their implementation. The results display a variety of formats and solutions through which the teachers’ abilities can be empowered in this direction, from dedicated courses, or modules, to virtual simulation. The participation in playful pedagogy courses significantly contributes to a positive attitude and the successful integration of this approach into teaching-learning-assessment activities. The analysis argues for the need to introduce such training programs in the pre-service teacher education and highlights the implications for the measures to be adopted.