bluuebunny/crossref_metadata_2025 huggingface dataset:
Huatan Tongluo Decoction Inhibits Inflammatory Infiltration and Airway
Remodeling by Attenuating TGF-β1/Smad2/3 and Oxidative
Stress-mediated NF-kB/HIF-1α/MMPs Signaling Pathway in Chronic
Asthma Mice
Authors: Lao Huimin , Chen Mengqi , Liu Xuanyu , Li Libo , Li Qian , Zhang Baoqing
Published: January 2023

Background:

Asthma is a common chronic respiratory disorder characterized by inflammation
and remodeling of the airways.

Aims:

This study aimed to identify the inhibitory effects of Huatan Tongluo decoction (HTTLD) on airway
inflammation and associated remodeling mechanisms.

Methods:

Mice were immunized with ovalbumin (OVA) for 8 weeks to generate chronic asthma mouse
models (CAS), which were randomly divided into 4 groups administrated with pachyman, dexamethasone
(DEX), HTTLD, and without anything (CAS model), while mice who administrated saline were assigned
as the control group. Hematoxylin-eosin (H&E) and Masson trichrome were used to determine inflammatory
infiltration and airway remodeling (fiber deposition). Inflammatory cytokines, including VEGF,
PDGF, and TGF-β1, were analyzed using ELISA. The gene transcriptions and expressions of MMP-9,
TIMP-1, VEGF, HIF-1α, NF-kB, and β-actin were evaluated using RT-PCR and Western blot, while the
expression of p-Smad2/3 was determined by Western blot.

Results:

HTTLD inhibited inflammatory infiltration and airway remodeling (reducing airway wall thickness
and decreasing fiber deposition) of lung tissues in the CAS mouse model. HTTLD markedly attenuated
levels of TGF-β1, VEGF, and PDGF compared to those of mice in the CAS model group (p < 0.05).
HTTLD significantly reduced the secretion of matrix metalloproteinases (MMP-9 and TIMP-1) and the
expression of NF-kB/HIF-1α compared to mice in the CAS model group (p < 0.05). HTTLD prominently
downregulated phosphorylated levels of the Smad2/3 molecule (ratio of p-Smad3/2/Smad2/3) compared
to mice in the CAS group (p < 0.05).

Conclusion:

HTTLD inhibited inflammatory infiltration and airway remodeling in an OVA-induced
chronic asthma mouse model by attenuating the TGF-β1/Smad2/3 signaling pathway and suppressing the
oxidative stress-mediated NF-kB/HIF-1α/MMPs signaling pathway.
Value of CT and MR Imaging in Assessment of Loco-regional Ablated
Hepatocellular Carcinoma using LI-RADS Treatment Response Algorithm
(version 2018)
Authors: Abd-Elsalam Sherief , Zarad Carmen Ali , Elagawy Waleed , Hasan Basma Badreldin , Abo Shanab Waleed S.
Published: January 2023

Aim:

The aim of this work is to evaluate the role of multiphasic CT and dynamic contrast
enhanced MRI using LI-RADS treatment response algorithm (version 2018) and the added values of
diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps in the assessment
of loco-Regional ablated Hepatocellular Carcinoma (HCC).

Methods:

This study included 45 patients with 50 loco-Regional ablated HCC lesions. All patients
underwent multiphasic CT scan, diffusion weighted and dynamic contrast enhanced MRI. The reference
standards for assessment were based on serum alpha-fetoprotein level and dynamic contrast
enhanced MRI.

Results:

Multi-phasic CT had moderate sensitivity (87.5%) and high specificity (100%) for assessment
of HCC LI-RADS treatment response algorithm. Dynamic contrast enhanced MRI had high
sensitivity (100%) and specificity (100%) for the assessment of HCC LI-RADS treatment response
algorithm. The sensitivity and specificity of DWI to diagnose HCC malignant residual or recurrence
were 93.7% and 100%, respectively, with very good performance. The mean ADC values of the
malignant residual or recurrence were significantly lower than that of benign post-ablation tissue
changes areas and the best ADC cutoff value for differentiation between viable and nonviable lesions
was 1.1x10-3 mm²/s.

Conclusion:

Performance of dynamic contrast enhanced MRI is better than that of multiphasic CT in
the assessment of LIRADS treatment response algorithm. DWI and ADC maps could be used as
ancillary methods for differentiation between viable and non-viable loco-regional ablated HCC lesions
and should be included in LR-TR treatment response algorithm.
Middle Ear Teratoma: Clinical and Imaging Features
Authors: Liu Jun-hua , Huang Wen-hu , Liu Yin , Zhang Fang , Sha Yan
Published: January 2023

Background:

Teratoma is a true neoplasm composed of a number of different types of tissue
derived from the three germinal layers but rarely occurs in the middle ear (ME). The features of
middle ear teratomas (MET) have not been well described.

Objective:

The objective of this study is to explore the clinical and imaging features of MET, and report
2 rare cases of MET with ear malformation that have never been reported.

Materials and Methods:

The clinical, CT and MRI data of 8 patients with a pathological diagnosis of
MET were collected and retrospectively mined, and 14 patients with MET reported in previous literature
were also reviewed.

Results:

① Female, left ear predominance in MET, and the most common symptoms were otorrhea
and hearing loss. ② On CT and MRI, the MET presented as an irregular soft tissue mass that was
heterogeneous, with fatty tissue and involved multiple sites, and the ET and tympanum were correspondingly
expanded and locally destroyed. ③ Mictotia with MET in two patients was presented,
which was the first report.

Conclusion:

MET has female sex and left ear predominance. CT and MRI can be used to diagnose
MET and display its extent and its relationship to the carotid canal in detail. Complete surgical excision
is the definitive treatment.
Prophylactic Agents for Preventing Cardiotoxicity Induced Following
Anticancer Agents: A Systematic Review and Meta-Analysis of Clinical
Trials
Authors: Amin Hashemipour Seyed Mohammad , Valizadeh Rohollah , Keshavarzian Ehsan , Sadighpour Tella , Mortazavizadeh Seyed Mohammadreza , Soltani Mohammadhossein , Motevalipoor Amir Farzin , Khamas Shahriyar Shahbazi , Moazen Mohammad , Kogani Mohammad , Hosseinpour Hamid
Published: January 2023

Background:

Anthracyclines can improve survival in many types of malignancies, but
dose-dependent and irreversible results following the use of anthracyclines have been associated
with cardiomyopathy. This meta-analysis aimed to compare the effects of prophylactic agents for
preventing cardiotoxicity induced following anticancer agents.

Methods:

In this meta-analysis, Scopus, Web of Science, and PubMed were surfed for articles
published by December 30th, 2020. The keywords were angiotensin‐converting enzyme inhibitor
(ACEI), enalapril, captopril, angiotensin receptor blocker, beta blocker, metoprolol, bisoprolol,
isoprolol, statin, valsartan, losartan, eplerenone, idarubicin, nebivolol, dihydromyricetin, ampelopsin,
spironolactone, dexrazoxane, antioxidants, cardiotoxicity, n-acetyl-tryptamine, cancer, neoplasms,
chemotherapy, anthracyclines, doxorubicin, daunorubicin, epirubicin, idarubicin, ejection fraction or a
combination of them in the titles or abstracts.

Results:

A total of 17 articles out of 728 studies examining 2,674 patients were included in this
systematic review and meta-analysis. Ejection fraction (EF) values in the baseline, 6-month, and
12-month follow-up in the intervention group turned out to be 62.52 ± 2.48, 59.63 ± 4.85, and
59.42 ± 4.53, whereas in the control group appeared to be 62.81 ± 2.58, 57.69 ± 4.32, and 58.60 ±
4.58, respectively. Through comparison of the two groups, EF was found to increase in the
intervention group by 0.40 after 6 months (Standardized mean difference (SMD): 0.40, 95%
confidence interval (CI): 0.27, 0.54), thus proving higher than that of the control groups
following the cardiac drugs.

Conclusion:

This meta-analysis showed that prophylactic treatment with cardio-protective drugs,
including dexrazoxane, beta blocker, and ACEI drugs in patients undergoing chemotherapy with
anthracycline, have a protective effect on LVEF and prevent EF drop.
Natural Products and Derivatives Applied for Skin Care: An Updated
Review
Authors: Kumar Virender , Kumar Nakul , Singh Gajendra
Published: January 2023

In contemporary cosmetics, botanicals and natural extracts remain vital components and
have been used in formulations since ancient times. However, natural and botanical products can
still be highly effective in treating aging skin, even though they are becoming more technological
and invasive. Many natural products are being elucidated through biochemical mechanisms of action,
correlating with traditional uses of many plants for skin benefits. Different formulations of
medicinal and pharmaceutical substances incorporate synthetic molecules and chemicals, which is
the principal cause of dermal toxicity. Consumers' awareness about personal health and safety and
the desire for safer cosmetics free of harmful chemicals have driven the cosmetics and personal care
market toward natural ingredients. The commercialization of natural products derived from herbs
and bees is possible. Our purpose is to present a comprehensive and critical review emphasizing the
benefits of natural products for skin care, women's purchasing patterns, and updated information
about natural products.
The Queen Honey Bee: Introduction, Development, Pheromones, Mating, and Role in the Colony
Authors: Marwaha Lovleen
Published: January 2023

 Apis mellifera (2n=32), commonly known as the European honey bee or the
Western honey bee, is a eusocial insect. Each honey bee colony is a composite unit of
thousands of bees, with three different castes: a polyandrous reproductively active
queen; thousands of workers; and a few hundred drones. The queen and the workers
represent the female caste that develops from fertilized eggs, whereas the drones are
male bees formed from unfertilized or fertilized eggs. In the case of the female honey
bees, the phenomenon of polyphenism can be easily highlighted, which is the
developmental plasticity of the same genomic contents to express differently as per
environmental cues. During the queen larval developmental phase, the exclusive diet is
royal jelly, which induces hyper-secretion of juvenile and ecdysone hormones that
ultimately cause sequential activation of certain genetic elements, specifically after 3rd
instar onward. For the worker honey bee larvae, initially, the diet includes royal jelly
exclusively, followed by honey, pollen grains, and worker jelly, which collectively
direct development toward the worker caste. Furthermore, for harmonious social
interaction, the queen secretes certain volatile chemical bouquets including 9-
ODA(2E)-9-oxodecenoic acid), 9-HDA (9-hydroxy-(E)-2-decenoic acid), 10-HDA
(10-hrdroxy-2-decenoic acid), HVA (4-hydroxy-3-methoxyphenylethanol), HOB
(Methyl-p-hydroxybenzoate), 10-HDAA (10-hydroxydecanoic acid), OLA
(oligolactide), methyl oleate, decyl decanoate, linolenic acid, coniferyl alcohol, cetyl
alcohol, etc. The concerned pheromones facilitate the regulation of workers' behavior;
workers' ovarian suppression; retinue control; overall worker’s development
modulation; colonial product production; swarming tendency; pseudo-queen formation
suppression; mating, etc. The queen honey bee is polyandrous, as she mates with many
drones during the nuptial flight in 'Drone Congregation Areas (DCA)’, within about 2
weeks of her post-emergence. This chapter provides a comprehensive review of the
polyandrous queen honey bee; her synchronous developmental phases; her pheromone
dominance; her regulation and coordination of colonies; her mating preference and
habits; and her role in a composite hive. Subsequent chapters provide an elaborative
view of different aspects of the queen honey bees' life cycle.
The Queen Honey Bee Duties in the Composite Colonies
Authors: Marwaha Lovleen
Published: January 2023

 In a honey bee colony, a polyandrous queen bee performs two important duties predominantly. The first is reproduction, for modulation of colonial strength; and the second is the secretion of queen pheromones for regulation of social organization, developmental specification, colonial productivity control, retinue behaviour induction, worker ovarian suppression, foraging control, swarming reduction, other queen rearing inhibition, etc. In the female caste of honey bees, reproduction is uni-righted by a polyandrous queen, which mates preferably with multiple drones of other colonies during a nuptial flight in a Drone Congregation Area(DCA) and thereafter lays fertilised or unfertilized eggs depending on in-situ and ex-situ hive ambience, whereas worker honey bees perform the remaining tasks, including hive construction, brood rearing, foraging for food and nectar, honey production, protection and general organisation of the colony, pollen grain storage, water collection for the colony, ventilation in the hive, and the removal of carcases. In other words, worker bees perform all tasks except for reproduction and colony dominance. The specific duties assigned reflect the rectitudinous behaviour of the honey bee colony. Additionally, the specific division of labour enhances the competence of all honey bee castes. The Queen's honey bee is considerably fertile due to differential genomic expression, proteomics, and developmental specification. Further, her reproducibility is influenced by different biotic and abiotic factors prevailing within and outside the hive. In this chapter, a brief description of two predominant duties of the queen, including reproduction and pheromonal secretion, is highlighted. Subsequent chapters provide elaborative views of reproduction and pheromones. 
The Queen Honey Bee Morphology, Development, and Reproductive System
Authors: Marwaha Lovleen
Published: January 2023

The queen bee carries the same genetic information as worker bees. Still, the
genomic expression is variable, eventually resulting in the development of an
enormously sizeable female bee, with an enriched blend of pheromone possession, a
comparatively long life span, better immunity, development, and physiology.
Differential developmental patterns compared to the workers are due to the influence of
royal jelly, ultimately inducing differential genomic expression. Furthermore, with
profound pheromone secretion, the queen regulates the colony's development,
differentiation, reproducibility, behaviour, communication, and task management. This
chapter briefly describes honey bees' morphology, development, and reproductive
system development.
Influence of Queen Pheromones on Worker Ovarian PCD in Apis mellifera (Hymenoptera: Apidae)
Authors: Marwaha Lovleen
Published: January 2023

Queen honey bee imposes her reproductive dominance through the secretion
of volatile chemicals, especially from the mandibular gland, tergal and defour glands.
Further, queen pheromones and different larval diets; aggregately control the
differential expression of specific genetic elements. The altered transcriptomic activity
resulted in Programmed Cell Death (PCD) in the ovaries of worker honey bees.
Furthermore, after the hatching of workers, the specific degenerative process remains
continuous for a brief period, destroying numerous ovarioles. As a result, few
facultative functional ovarioles remain active in worker honey bees' ovaries. Available
literature also witnesses the formation of pseudo-queens or egg-laying workers.

This chapter provides insight into responsible queen pheromones for induction of
programmed cell death in worker honey bees' ovaries. The next chapter focuses on the
genetic elements for queen pheromones's-induced ovarian PCD in workers. 
The Polyandrous Queen Honey Bee: Biology and Apiculture
Authors: Marwaha Lovleen
Published: January 2023

The queen honey bee is known to mate with multiple drones, and can produce over a million offspring in its lifetime. Its presence is vital to the growth and survival of a beehive. This reference book is a detailed guide to queen honey bees. The book starts by providing deep insights into the fascinating biology of the queen honey bees, their morphometric features, developmental synchronicity, genetics, hormones, pheromones, colonial organization and swarming. Further, the book describes artificial queen rearing techniques that facilitate healthy bee colony growth and increase apiculture productivity. The book equips readers with all the knowledge they need to know about queen bee development, their role in the colony and improving the health of their colony.

Key Features

- 14 reader-friendly chapters that comprehensively present information about queen honey bees

- Comprehensive coverage about queen bee biology, including their physical morphology, genetics, proteomics, development and behavior (including worker and drone interactions)

- Information about the role of queen bees in colonial organization and life-cycle events

- Practical information that helps to improve bee colony health for research and apiculture (disease mechanisms and control, artificial breeding)

The book is an essential primary reference on queen honey bees for biology and entomology students, academicians and researchers at all educational levels. Apiculturists, bee keeping enthusiasts, and general readers interested in honey bees can also benefit from the breadth of information presented.
The History of Biotechnology and the Law
Authors: Stasi Alessandro , Chiang David Tan Weng
Published: January 2023

The chapter explores the historical development of a legal framework for
biotechnology regulation. It aims to provide an overview of the history of
biotechnological practices and the development of modern concepts. It describes how
people had used biotechnology processes for millennia, noting that the rise of modern
medicine can only be traced back to the 19th century, when the progress of science and
the advances in laboratory techniques contributed to the creation of a medical market.
The chapter ends by analyzing the origins of the U.S. Food and Drugs Administration
and the Food and Drugs Act of 1906. 
Incidence of Climate on the Number of Admissions and Deaths Due to Cerebrovascular Diseases Through Mathematical Modeling In Sagua La Grande, Villa Clara, Cuba
Authors: Freyre Jorge Luis Alonso
Published: January 2023

The number of deceased cases and admissions for annual cerebrovascular diseases were modeled in Sagua la Grande, Villa Clara province, Cuba, between 1993 and 2017. A statistical description of these two variables was made, with an average admission of 148 .7 cases, with a standard deviation of 24.9. The deceased had an average of 35.7 with a standard deviation of 13.2, the results were obtained using the Regressive Objective Regression (ROR) methodology. The impact of the minimum temperature and atmospheric pressure of the Sagua La Grande station was studied, reaching the conclusion that as the minimum temperature increases, the income and deaths increase, so this impact is related to the climate change, when the minimum temperature increases by 1 °C, deaths increase by 9 cases, while when the maximum temperature increases by 1 °C, deaths increase by 11.6 cases. In the case of revenue, as the atmospheric pressure increases by 2 hPa, the amount of revenue decreases by 1 case.
Juventudes huarpes de Mendoza (Argentina): ¿políticas públicas en los territorios o necropolíticas?
Authors: Rosales Carla Daniela , Quiroga Spatola Marian Luciana , Garcia Ortiz Mariana , Ochoa Natalia
Published: January 2023

En nuestra trayectoria como trabajadoras sociales hemos recorrido diversas instituciones públicas del secano de Lavalle (Mendoza, Argentina) y coincidimos al comenzar a desarrollar un estudio que pueda abordar algunos interrogantes en torno a las políticas públicas que atraviesan a las juventudes huarpes[1] en la actualidad.[2] Partimos de una mirada crítica acerca de las políticas públicas vigentes en estos territorios, las cuales, dada su constante insuficiencia y precariedad —o inexistencia—, cuestionan fuertemente el reconocimiento que de estas poblaciones rurales e indígenas tiene el propio Estado, en su rol de garante de derechos, especialmente frente a las vulneraciones extremas que ellas viven. Es a partir de esta trayectoria y vinculación con las comunidades huarpes, en particular con las generaciones jóvenes, que entendemos que las nociones de necropolítica (Mbembe, 2011) y de duelidad (Butler, 2020) vienen a contribuir fuertemente al análisis y al diálogo entre la teoría y la práctica situada. Este avance de investigación, predominantemente cualitativo, se nutre de nuestros espacios biográficos, donde nuestras trayectorias laborales y profesionales en el campo público se entrecruzan con el análisis teórico. Este trabajo aporta pistas para analizar las particulares formas que las políticas públicas, específicamente las destinadas a las juventudes, adquieren en territorio huarpe. Estos bordes entre lo rural/indígena, lo público/comunitario, el Estado/territorio y la política social/beneficencia se entrecruzan, complejizando la realidad de las comunidades indígenas. [1] Etnia preexistente al Estado nacional. [2] Este avance de investigación se realiza con el financiamiento del Colegio Profesional de Trabajo Social de la provincia de Mendoza (2022-2023). Actualmente se encuentra en ejecución.
Lxs niñxs y las mujeres de Casa de Gobierno en AtyKwakúmuke (Pueblo bello, Colombia): pautas de crianza y acceso a la justicia sexual en la Sierra Nevada
Authors: Restrepo Galvis Laura Sofía , Santamaria Ángela , Izquierdo Digneris , Moreno Reza Gabriel Elias
Published: January 2023

Este artículo presenta las experiencias de crianza y formación para el liderazgo de un grupo de niñas y mujeres arhuacas en el municipio de AtyKwakúmuke en Pueblo Bello, Cesar (Colombia), desde una perspectiva femenina arhuaca de la administración de la justicia propia en casos de violencia sexual. En este sentido, nos preguntamos: ¿quiénes son lxs niñxs y las mujeres que hacen parte de este proceso de atención y prevención de la violencia sexual en el pueblo arhuaco? ¿Cómo participan las lideresas y sus hijxs en la escuela de niñxs de Casa de Gobierno?

Desde el punto teórico cruzamos dos tipos distintos de literatura. Por un lado, elementos teóricos sobre la crianza (García Peralta y García Peralta, 2019; Braun y Clarke, 2006); por el otro, los estudios de los procesos de justicia de mujeres indígenas (Sieder, 2016). Desde el punto de vista metodológico proponemos procesos de investigación/acción participativa feminista (Lykes y Crosby, 2013) a través de bitácoras, cartografías, corpografías y elaboración de muñecas como artefactos memoriales que valorizan los conocimientos tradicionales femeninos arhuacos, reflexionando sobre la justicia y la gobernanza de niñxs y mujeres.
Translanguaging and English as a Lingua Franca in the Plurilingual Classroom
Authors: Mendoza Anna
Published: January 2023

This book explores the use of multilingual practices such as translanguaging, code-switching and stylization by speakers of less commonly taught languages. It investigates how students use these languages alongside English as a lingua franca to participate in classroom tasks and social interactions in secondary classrooms in Hawai’i.
Effect of Havruta learning method on training satisfaction of military recruits through the mediation of inner motive, creativity, and military service value
Authors:   Department of Industrial and Management Engineering, Hanbat National University, Daejeon, South Korea, Kim Soo-Yun , Lee Dong-Hyung ,   Department of Industrial and Management Engineering, Hanbat National University, Daejeon, South Korea
Published: January 2023

The purpose of this study is to analyze the effect of recruit training applied with the Havruta learning method on training satisfaction through inner motive, creativity, and military service value using a structural equation model. Havruta is a learning method in which two people ask questions and discuss in pairs, and it is an effective learning method to enhance inner motive, creativity, and military service value. For this purpose, inner motive, creativity, military service value, and training satisfaction were measured for 472 recruits who received training applying the Havruta learning method. Statistical analysis such as path analysis and multi-parameter model analysis was performed by inputting the measured values into the structural equation model (SEM). As a result of the CFA (Confirmatory Factor Analysis) of the SEM, the fitness index was found to be suitable as TLI=0.914, CFI=0.928, and RMSEA=0.080. Also, the validity index satisfied more than the criteria (AVE>0.5 and CR>0.7). As a result of the study, the Havruta effect of recruit training enhances inner motive, creativity, and military service value. As for the mediating effect of training satisfaction, inner motive and military service value had a significant effect, but creativity did not. The army needs to actively review the Havruta learning method in order to improve the satisfaction of recruit training of MZ generation soldiers. In the future, it will be a more meaningful study if you confirm the effect of training with the Havruta learning method on the training achievement of recruits.
Exploratory Laparotomy for Encapsulated Gossypiboma: A Rare Case
Authors: Costa Leandro Jaime Barreto , Carvalho Mário Gissoni de , Carvalho Júnior Mário Gissoni de
Published: January 2023

Gossypiboma, term derived from the latin ‘gossypium’ (cotton) and the swahilli ‘boma’ (place of concealment) is the term form retained surgical sponge. Two usual responses to retained mops are exudative inflammatory reaction to develop a mass. Intraluminal migration is rare, leading to obstruction. Patient may develop symptoms of abdominal pain, nausea, vomiting and weight loss resulting from obstruction or a malabsorption syndrome caused by multiple intestinal fistulas or intraluminal bacterial overgrowth. Early recognition of this entity will ensure prompt diagnosis and appropriate treatment, reducing morbidity and mortality in such patients.
Comparison of the effects of progressive supervised and home program exercise therapy in mild–moderatehallux valgus
Authors: Oztarsu Merve Betul , Oksuz Sevim
Published: January 2023

Aim:To compare the effects of progressive exercise therapy, performed under the supervision of a physiotherapist and given as a home program in individuals withhallux valgus.Methods:Participants were randomly divided into two groups. While one group performed the exercises under the supervision of a physiotherapist, the other group did the same program at home.Results:The amount of decrease in foot adduction angle, pain level while walking, and right foot navicular height of individuals receiving treatment under the supervision of a physiotherapist were significantly higher.Conclusion:The exercise program applied under the supervision of a physiotherapist was more effective in reducing the first toe adduction angle, medial longitudinal arc height, and pain, improving dynamic balance and functional capacity.
Study on the Strength of Stainless-Steel Fiber Rein-forcement Concrete
Authors: Bragadeeswaran T. , Naveenprasath S.
Published: January 2023

Abstract: Stainless steel fibers have been used as reinforcement in concrete for several decades. These fibers have excellent corrosion resistance, high strength and ductility, and can improve the overall mechanical properties of concrete. The use of stainless steel fibers in concrete can improve the toughness, flexural strength, and impact resistance of the material, making it ideal for use in harsh environments or high-stress applications. This paper reviews the recent research on the use of stainless steel fibers in concrete, including the effects of fiber size, shape, and content on the mechanical properties of the material, as well as the potential benefits and limitations of using stainless steel fibers in concrete.
Bael Patra as Anti-Oxidant: A Review
Authors: Vispute Mrs. Yogita M , Thosar Ms. Namrata , Chavarkar Mr. Preet
Published: January 2023

Abstract: Bael, Aegle marmelos (Linn.) Correa ex Roxb., a tree of Indian origin is known from pre-historic time. It has a great mythological significance for Hindus. Utilization of bael in day-to-day life has great nutritional, environmental as well as commercial importance. It has been in use from time immemorial in traditional systems of medicine for relieving constipation, diarrhoea, dysentery, peptic ulcer and respiratory infections. Important medicinal properties of bael are antidiabetic, antimicrobial, anti-inflammatory, antipyretic, analgesic, cardioprotective, antispermatogenic, anticancer and radioprotective. The present review deals with chemical profile such as antioxidant property and its uses.
The effect of self-elasticity and internal motivation on achievement goal propensity in tennis activities of the elderly beginner by matching the behavior of the elderly learner and leaders
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Im Ji Heon
Published: January 2023

Objectives The purpose of this study was to study and verify the effects of ego resilience and internal motivation on the achievement goal orientation in elderly learner-leader behavior consistent in elderly beginer tennis activities.
Methods To obtain the results, a survey was conducted on the Magic Tennis Group in the Senior Classroom of the Korea Tennis Association and Ichon, Ttukseom beginer Tennis Group and conducted factor analysis, frequency and percentage, and reliability analysis (Cronbach's α) using SPSS 25.0 and AMOS 5.0 statistical programs to analyze the results.
Results First, ego resilience has shown significant consequences for elderly learner-leader behavior consistent. Second, internal motivation showed significant results in elderly learner-leader behavior consistent. Third, the elderly learner-leader behavior consistent showed significant results in achievement goal orientation.
Conclusions Although this study suggested the effect of ego resilience and inner motivation on achievement goal orientation objectives in combination with elderly learner-leader behavior consistent, there was a limit to the outcome as a limited variable called the senior beginner tennis group when identifying achievement goal orientation objectives. Based on the results of this paper, it is believed that various psychological skills development should be studied as a group of various at sports sites.
The Effect of Teacher's Play Support Competency on Childhood's Self-efficacy: The Mediating Effect of Teacher-Child Interaction
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Yoo Mina , Hwang Hae Shin
Published: January 2023

Objectives The purpose of this study was to examine the effect of teacher's play support competency on childhood's self-efficacy and to verify the mediating effect of teacher-child interaction.
Methods The study participants were 413 3-years-old, 4-years-old, and 5-years-old children and 40 teachers in childcare centers and kindergarten. The teacher's play support competency, childhood's self-efficacy, and teacher-child interaction tools were evaluated by the child's teacher. The collected data were subjected to Pearson's correlation analysis and Baron and Kenny's three-stage mediating regression analysis using the SPSS 21.0 program, and then the significance of the mediating effect was verified through Sobel test.
Results First, there was the significant correlation between teacher's play support competency, childhood's self- efficacy, and teacher-child interaction. Second, it was found that the teacher's play comprehension competency mediated the teacher-child interaction and had an indirect effect on the cognitive, physical, and social emotional efficacy of children. Third, it was found that the teacher's play observation and analysis competency had an indirect effect on the social and emotional efficacy of children by full mediation the teacher-child interaction. Fourth, it was found that the teacher's play operation competency had an indirect effect on the cognitive and social emotional efficacy of children by full or partial mediation the teacher-child interaction. Fifth, it was found that the teacher's play response and communication competency had an indirect effect on the cognitive, physical, and social emotional efficacy of children by full mediation the teacher-child interaction.
Conclusions The results of this study suggest that it is important to develop teacher's play support competency and improve the quality of teacher-child interactions in order to improve childhood's self-efficacy.
The Effect of the Feedback Type of Physical Education Teachers on Grit and Tripartite Efficacy of Middle School Students
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Park Ji-Heum , Park Jong-Lyoul
Published: January 2023

Objectives The purpose of this study is to find out the effect of the feedback type of physical education teachers on the grit and tripartite efficacy of middle school students.
Methods To this end, 497 copies of data were analyzed, and the validity and reliability were verified by performing frequency analysis, exploratory factor analysis, and reliability analysis to understand the general characteristics of the research subject. In addition, correlation analysis and multi-linear regression analysis were conducted to find out the relationship between feedback type and grit and tripartite efficacy.
Results First, it was found that corrective and positive feedback had an effect on effort continuity, which is a sub-factor of grit. In addition, positive and negative feedback were found to have an effect on interest persistence, which is a sub-factor of grit. Second, positive and corrective feedback were found to have an effect on self-efficacy and relationship inference self-efficacy, which are sub-factors of tripartite efficacy. In addition, positive and corrective feedback and negative feedback were found to have an effect on self-efficacy by others. Third, self-efficacy, self-efficacy by others, and relationship inference self-efficacy, which are three sub-factors of tripartite efficacy, were all found to affect effort persistence, and self-efficacy by others was found to have an effect on interest consistency.
Conclusions Therefore, it was found that depending on the type of feedback of the physical education teacher, it had a significant effect on the grit and tripartite efficacy of middle school students.
The Relationship between Smartphone Addiction Tendencies and Academic Burnout in (under)Graduate Student: The Mediating Effects of Sleep Quality and Academic Procrastination
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Yeong-Eun , Park Kee-Hwan
Published: January 2023

Objectives The purpose of this study was to examine the mediating role of sleep quality and academic procrastination in relationship between smartphone addiction tendencies and academic burnout for university students.
Methods The Self-report survey was conducted on 426 (under)graduate students. To measure the variables, the S-scale-A (Korean Smartphone Addiction Proneness Scale for Adults), SQS (The Sleep Quality Scale), API (Aitken Procrastination Inventory), and MBI-SS (Korean version of Maslach Burnout Inventory Student Survey) were included in the survey.
Results The findings of this study showed that smartphone addiction tendencies, low sleep quality, academic procrastination, and academic burnout were all significantly correlated in a positive direction. Furthermore, the results indicated that low sleep quality and academic procrastination had a sequential mediating effect on the relationship between smartphone addiction tendencies and academic burnout.
Conclusions The results specify the mediating role of low sleep quality and academic procrastination in relationship between smartphone addiction tendencies and academic burnout for (under)graduate students. Finally, the clinical implications, limitations of this study and future research directions were suggested.
The Impact of Classfit Training on Physical Fitness and Prefrontal Executive Function in Children
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Hyung Chul , Kim Kyeong Lae
Published: January 2023

Objectives The purpose of this study is to investigate the impact of the 12-week Class-fit training exercise program on physical fitness and prefrontal executive function in elementary school students and provide base data needed to use Class-fit training as physical fitness and prefrontal executive function improvement program of students.
Methods In order to accomplish the purpose of this study, 36 sixth-grade students at E elementary school located in Seoul, were selected by convenience sampling and allocated 18 students each for the exercise group and the control group. Each group was measured for physical fitness and prefrontal executive function before and after the exercise. Class-fit training was implemented for 40 minutes of 3 times each week for 12 weeks.
Results The results obtained through this study are as follows. First, muscle endurance, cardiovascular endurance, flexibility, power showed interaction effects in the group and time. Second, raw color-word score showed interaction effects in the group and time. Word raw score, color raw score showed significant differences in timing, particularly the post score of exercise group increased significantly.
Conclusions In conclusion, 12-week Class-fit training had positive effect on elementary school students for physical fitness and prefrontal execution function. Class-fit training will make a contribution to the exercise program to help improve physical fitness and cognitive function.
Adaptação do Pet-Saúde no contexto da pandemia e de atividades online: um relato de experiência
Authors: Casseb Gabriela Éleres , Alves Lucivaldo Almeida , Delgado Danilo Souza , Lima Juliana de Silva , Pessoa Monaliza dos Santos , Lima Nilo Cesar Raiol de
Published: January 2023

A interdisciplinaridade acadêmica é um dos fatores que proporcionam o desenvolvimento de práticas interprofissionais, que são essenciais para efetividade do atendimento integral ao usuário do Sistema Único de Saúde (SUS). O Programa de Educação Pelo Trabalho Para a Saúde (PET-Saúde), instituído pelo Ministério da Saúde, visa fomentar a formação de profissionais da área por meio da integração do eixo ensino-serviço-comunidade, norteados pelo interprofissionalismo nas Unidades Básicas de Saúde (UBS). No programa, os profissionais devem trabalhar em equipe, sob ótica interprofissional e com foco em situações-problema reais. Neste artigo, buscou-se relatar o desenvolvimento de novas estratégias para a manutenção das atividades de ensino e saúde do programa, devido à pandemia do novo coronavírus. Para isso, ocorreu a substituição das atividades presenciais pelo uso de Tecnologias de Informação e Comunicação (TIC) em plataformas online. Foram realizados cursos de qualificação, fóruns regionais e nacionais para discussão das lacunas e instabilidades do SUS e do programa, além da produção de folders, cartilhas e vídeos voltados para educação em saúde da população de acordo com cada realidade. A experiência do PET-Saúde durante o contexto pandêmico teve resultados positivos no que se refere à aproximação interprofissional, geração de arcabouço teórico e criação de atividades de educação em saúde para a comunidade. Todavia, há dúvidas quanto à capacidade do material de abranger toda a população-alvo, visto que foi necessária a interseção dos profissionais das UBS para concretizar ações online, gerando incertezas quanto ao alcance de indivíduos sem acesso ao meio virtual.
A violência contra a mulher com deficiência e sua invisibilidade no âmbito do Sistema Único de Saúde
Authors: Souza Brenna Oliveira de , Vieira Francilene de Sousa
Published: January 2023

A violência contra as mulheres (VCM) é um episódio complexo e multifacetado, envolvendo distintos sistemas, aspectos sociais, mentais, estabelecidos pelas diferenças de gênero. O objetivo deste artigo é descrever as principais violências contra a mulher com deficiência e sua invisibilidade no âmbito do Sistema Único de Saúde (SUS). Trata-se de um estudo de revisão integrativa, realizado nas seguintes bases de dados: Electronic Library Online (SciELO), Portal Regional da Biblioteca Virtual em Saúde (BVS), contemplando a Organização Pan-Americana da Saúde (Opas)/OMS, Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde (Bireme), incluindo ainda a Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs) e Medical Literature Analysis and Retrieval System Online (Medline), sendo os idiomas português, inglês e espanhol, com uma amostra final de 14 artigos. Os textos foram organizados segundo seu tema central de discussão em categorias. Este estudo procurou discutir aspectos acerca da violência contra a mulher, em especial mulheres portadoras de deficiências, tendo em vista a falta de atenção e compreensão sobre esse fenômeno social no público especificado. Embora haja diversos recursos de promoção dos direitos das mulheres e combate à violência por elas sofridas, muitos casos de violência são banalizados, não recebendo as devidas providências para redução dos índices de violência. Por último, ressalta-se a necessidade de esforços para diminuição das vulnerabilidades do próprio setor de saúde, com o intuito de aperfeiçoar suas ações e a necessidade de mudança gradativa do perfil dos profissionais, a fim de propiciar o melhor atendimento à vítima.
Saúde mental da população brasileira no contexto da COVID-19 (SARS-CoV-2): revisão de literatura
Authors: Marinho Ana Lilian de Aguiar , Barakat Roberta Duarte Maia , Cavalcante Alan Rodrigues , Silva Francisco Régis da
Published: January 2023

Este estudo objetiva refletir acerca da saúde mental da população brasileira durante a pandemia do coronavírus (SARS-CoV-2) por meio de uma revisão integrativa da literatura. Pondera-se sobre a saúde mental como uma questão de saúde pública em tempos de pandemia para além dos danos biológicos e sociais. Para tal, acessaram-se as bases de dados Medical Literature Analysis and Retrieval System Online (MEDLINE), Scientific Electronic Library Online (SciELO) e Latin American and Caribbean Health Sciences Literature (LILACS) no período de 15 de julho a 15 de agosto de 2020 em busca de trabalhos produzidos no Brasil sobre o tópico. Foi identificado que os sentimentos mais presentes na população são de ansiedade, estresse, depressão e alteração no sono, ocasionados principalmente pelo medo de adoecer e morrer. Os grupos mais afetados por esses sentimentos são os profissionais de saúde que estão na linha de frente do combate ao coronavírus e pessoas com transtornos mentais preexistentes. Fatores como os condicionantes sociais, as fake news e o distanciamento social estão entre os maiores responsáveis pelo aumento desses sentimentos nas pessoas. Houve também alteração no comportamento da população no tocante ao aumento do consumo de bebidas alcoólicas. Concluiu-se a necessidade de uma maior assistência à saúde mental da população para que os impactos da pandemia não sejam tão duradouros quanto relatam os estudos levantados.
O uso de fitoterápicos no tratamento do Diabetes Mellitus: uma revisão da literatura
Authors: Cuzzuol Vitor Realli Gaspar , Leal Carina Maria Dalmonech Loterio , Rosetti Késia Alves Gomes , Damasceno Natalia Salvador de Souza
Published: January 2023

No Brasil, aproximadamente 9,1 milhões de pessoas são portadoras de diabetes mellitus, uma doença proveniente de falhas nos mecanismos metabólicos e que tem por consequência a hiperglicemia e várias outras complicações. Entre os programas ofertados pelo Sistema Único de Saúde para o seu controle, destaca-se a fitoterapia, que vem se mostrando bastante eficaz, conforme evidenciam os resultados de diferentes estudos. Por meio deste artigo de revisão, propõe-se conhecer e analisar a produção científica publicada acerca do uso de fitoterápicos e plantas medicinais no tratamento do diabetes mellitus. Para tal, optou-se pela realização de um estudo bibliográfico, em que foram analisadas publicações a partir de 1990. As plantas que obtiveram resultados positivos em diversos estudos foram as espécies: Bauhinia forficata (pata-de-vaca), Syzygium cumini (jamelão), Sphagneticola trilobata (insulina), Cissus sicyoides L (insulina vegetal), carqueja, tintura de mororó, Stevia rebaudiana, Chrysobalanus icaco Lin (abajeru), Myrcia multiflora (pedra-ume-caá) e epicarpo da romã. As evidências acerca dos benefícios proporcionados pelo uso das plantas medicinais corroboram a necessidade de investimento para sua utilização adequada e melhoria da qualidade de vida do paciente diabético.
Comportamento suicida e ansiedade entre usuários de um centro de atenção psicossocial no nordeste brasileiro
Authors: Santos Bruno Andrade , Freitas Carla Kalline Alves Cartaxo , Santos Thaiane Santana , Rodrigues Iellen Dantas Campos Verdes , Santos Joyce dos Anjos , Santos José Marcos de Jesus
Published: January 2023

O comportamento suicida tem sido conceitualizado como um contínuo de pensamentos e comportamentos desde a ideação até o suicídio em si. O objetivo deste trabalho é analisar a prevalência e os fatores associados ao comportamento suicida e o nível de ansiedade entre usuários de um Centro de Atenção Psicossocial (CAPS). Trata-se de um estudo observacional e transversal realizado entre julho e setembro de 2019 com 188 usuários adultos de um CAPS em Lagarto, Sergipe. Utilizou-se o Inventário de Ansiedade de Beck e a Escala de Avaliação do Risco de Suicídio de Columbia. Os resultados mostraram que, durante a vida, a prevalência de ideação suicida foi de 52,7% e de tentativas efetivas de suicídio, 31,8%, sendo maior entre pessoas com renda familiar menor que um salário mínimo (RP: 1,36, IC 95%: 1,07-1,56; RP: 1,97, IC 95%: 1,19-2,70, respectivamente). Com relação à ansiedade, 27,7% apresentaram ansiedade moderada e 21,8%, severa. A ansiedade severa e a tentativa efetiva de suicídio foram mais prevalentes no sexo feminino (RP: 2,70, IC 95%: 1,23-2,83; RP: 1,74, IC 95%: 1,23-1,84, respectivamente). A tentativa efetiva de suicídio se mostrou associada à ansiedade severa (RP: 2,99, IC 95%: 2,08-5,19). Foram encontradas prevalências elevadas e inter-relações da ideação suicida, tentativa efetiva de suicídio e ansiedade severa entre os usuários, com influência do sexo e renda familiar.
Espaço estamira: experiência inovadora em educação permanente com residentes de saúde mental
Authors: Silva Millena Raianny Xavier da , Lima Anna de Cássia Pessoa de , Lira Ana Lúcia da Silva , Souza Carolina Alves Barbosa de , Santos Israel Braz Nunes dos , Silva Nataly Regina da
Published: January 2023

Os processos de trabalho em equipes multiprofissionais são permeados de desafios. A Educação Permanente em Saúde é uma estratégia que visa transformar práticas em saúde nos âmbitos de ensino-aprendizagem, gestão, cuidado e controle social. Este artigo é um relato de experiência sobre o Espaço Estamira, projeto criado com o objetivo de implementar, em um programa de residência multiprofissional em saúde mental, um espaço formativo institucional onde os residentes pudessem intensificar o processo de ensino e aprendizagem em serviço de forma colaborativa, horizontal e autogerida, além de fortalecer a criação de vínculos e a qualificação do processo de trabalho. O Espaço Estamira acontece um turno por semana, com encontros para discussões de caso e supervisão compartilhada, discussão de textos, cinedebate, autocuidado e autogestão. Ficou evidente que entre os principais resultados do Espaço Estamira está a mudança de olhares e posturas em serviço das/os residentes, aprimorando a prática profissional e as intervenções em saúde mental. Também houve o estímulo à propagação das reflexões produzidas pelas/os residentes entre as equipes dos serviços em que elas/es atuavam. Concluiu-se que o Espaço Estamira possibilitou às/aos residentes a elaboração de análises críticas acerca dos projetos pedagógicos dos programas de residência, além de se mostrar relevante na construção de práticas profissionais potencializadoras do cuidado, alicerçadas em dimensões teórico-metodológicas, políticas e éticas comprometidas com as necessidades das/os usuárias/os do Sistema Único de Saúde (SUS).