bluuebunny/crossref_metadata_2025 huggingface dataset:
Immobilization of different products (enzymes) with chitosan
Authors:   Ecole de Biologie Industrielle, Cergy, France, Jucha Corentin , Groposila Constantinescu Diana ,   University of Agronomic Sciences and Veterinary Medicine of Bucharest, Romania, Jurcoane Stefana ,   University of Agronomic Sciences and Veterinary Medicine of Bucharest, Romania,   Asoc. Microbial Biotechnology Centre – BIOTEHGEN, Bucharest, Romania,   Academy of Romanian Scientists – AOSR, Bucharest, Romania
Published: April 2024

There is a strong emphasis on environmental preservation, and the agri-food sector is no exception. Nowadays, many food products are stored in plastic packaging, which can pose environmental challenges. That’s why, in this article, we explore a non-toxic, biocompatible, antimicrobial, antifungal alternative derived from natural sources: chitosan. We aim to develop a chitosan-based film, a biopolymer derived from chitin, to safeguard delicate fruits and vegetables from potential damage they may incur from harvest to sale. In this article, we delve into the immobilization of different enzymes using chitosan, the toxic impact of this compound, the immobilization of enzymes from various fruits, and finally, the study of coated fruits
HUBUNGAN LAMA PERIODE MENYUSUI DENGAN KEJADIAN KANKER PAYUDARA PADA WANITA USIA SUBUR
Authors: Salsabila Shofia Kamilina , Mediana Dian
Published: April 2024

Kanker payudara menempati posisi pertama jenis kanker terbanyak di Indonesia, menurut data GLOBOCAN tahun 2020 di Indonesia, lebih dari 22.000 kematian, dan 68.858 diagnosis baru. Lamanya menyusui memberikan manfaat bagi ibu, salah satunya adalah mencegah kanker payudara. Data tahun 2022 di Provinsi DKI Jakarta, terdapat penurunan jumlah pemberian ASI eksklusif pada dua tahun terakhir. Tujuan penelitian ini adalah ingin mengetahui hubungan pemberian ASI eksklusif dengan kejadian kanker payudara pada wanita usia subur. Metode penelitian observasional analitik dengan pendekatan case control. Teknik pemilihan sampel consecutive non random sampling dengan besar sampel kasus dan control masing-masing 35 responden. Pengumpulan data diperoleh dari data primer dengan wawancara menggunakan kuesioner. Data dianalisis menggunakan uji Chi Square dengan tingkat kemaknaan 0,05. Hasil uji univariat menunjukkan prevalensi kanker payudara pada wanita usia subur sebesar 50%, proporsi lama periode menyusui didapatkan mayoritas menyusui selama lebih dari 6 bulan dengan persentase 62,9%. Hasil uji bivariat menunjukkan terdapat hubungan bermakna antara lama periode menyusui (p=0,00) dan usia (p=0,00) dengan kejadian kanker payudara pada wanita usia subur. Sedangkan jumlah anak (p=0,45) dan tingkat pendidikan (p=0,80) menunjukkan hasil tidak berhubungan bermakna dengan kanker payudara pada wanita usia subur. Kesimpulan terdapat hubungan bermakna antara lama periode menyusui dan usia dengan kejadian kanker payudara pada wanita usia subur. Tidak terdapat hubungan bermakna antara jumlah anak dan tingkat pendidikan dengan kejadian kanker payudara pada wanita usia subur.
PENDEKATAN RADIOLOGIS PADA KASUS MALROTASI INTESTINAL DENGAN MIDGUT VOLVULUS
Authors: Rahmansyah Mulia , Velyani Dyani Pitra , Nareswari Gupita , Napitupulu Partogi , Wahab Revalita , Astien Astien , Tanaji Tandy Chintya , Miranti Pramesti Indri
Published: April 2024

Midgut volvulus is a condition in which the intestine has become twisted as a result of malrotation of the intestine during fetal development. It cause of an acute abdomen in neonates and important entity to be diagnosed urgently.  Midgut volvulus may lead to small intestinal ischemia and gangrene. The correct diagnosis depends on both high clinical suspicion and the radiologist’s ability to recognize the specific signs of malrotation and the normal variants that can lead to the wrong diagnosis. Radiological examination; such as abdominal x-ray, ultrasound and colon in loop play an important role in the diagnosis of volvulus . A color Doppler ultrasound examination may reveal a whirlpool sign, a colon in loop (CIL) examination may show an aberrant intestinal rotation, and a plain abdominal xray may show a double bubble sign due to midgut volvulus
PENDAMPINGAN PENASIHAT HUKUM TERHADAP TERDAKWA HUKUMAN PIDANA PENJARA DI ATAS 5 TAHUN
Authors: Christina Anggi Erika , Setiyono
Published: April 2024

Defendants who are sentenced to imprisonment for more than 5 years have the right to be accompanied by legal counsel. The formulation of the problem raised concerns the reason in examining the accused at the trial of a crime which carries a penalty of more than 5 (five) years in prison without beng accompanied by a legal adviser and the legal consequences of the decision handed down to the accused Tito Ariyanto who was examined and sentenced without beng accompanied by a legal adviser . This research method uses reAArch types based on normative research referring to secondary data. The nature of the research is descriptive and drawing conclusions using deductive methods. The results of the research and discussion, namely the actions of the defendant as a delivery agent for crystal methamphetamine/ecstasy were sentenced to imprisonment for 9 (nine) years without beng accompanied by legal counsel, so the conclusion of this investigation, the legal consequences caused by the defendant not beng accompanied by legal counsel, were not clearly explained by the law, but if you see several decisions of the Supreme Court then it becomes procedural law, that it is explained that if the defendant is not accompanied by legal counsel, then all legal products produced are null and void and contain legal defects
PERAMPASAN BARANG BUKTI UNTUK NEGARA TERHADAP TINDAK PIDANA NARKOTIKA (STUDI PUTUSAN NO: 342/PID.SUS/2022/PN.JKT.BRT)
Authors: Nabilla Andreas Vanya Shafa , Saragih Effendy
Published: April 2024

Abstract Currently, drugs are misused to be consumed, distributed and marketed without obtaining permission from the authorities. The circulation of narcotics without permission or illegally is mostly carried out by irresponsible parties. Arrangements for a Confiscation and seizure for evidence in a narcotics criminal act have been regulated by the law, namely in Article 87 and Article 101 of Law Number 35 of 2009 concerning Narcotics. In the case of Decision Number 342/Pid.Sus/2022/PN.Jkt.Brt, the property of a third party used by the defendant was confiscated by the state which resulted in material losses for third parties. Based on the analysis from Decision Number 342/Pid.Sus/2022/PN.Jkt.Brt, the subject matter raised is 1) How is the consideration of the judge’s decision on decision Number: 342/Pid.Sus/2022/PN.Jkt.Brt if it is related to the Evidence Procedure contained in Law Number 35 of 2009 and The result of this research is the decision of a narcotics crime Number: 342/Pid.Sus/2022/PN.Jkt.Brt, who has confiscated evidence for the State in the form of third party property in accordance with the provisions contained in Article 101 paragraph (2) of Law Number 35 of 2009 concerning Narcotics.
PENGELOLAAN KEUANGAN NEGARA HASIL TINDAK PIDANA KORUPSI BERDASARKAN UNDANG-UNDANG NOMOR 17 TAHUN 2003 TENTANG KEUANGAN NEGARA (STUDI PUTUSAN MAHKAMAH AGUNG 29/PID.SUS-TPK/2021/PN.JKT PST)
Authors: Marzani Devica Alivia , Edward Ferry
Published: April 2024

In the Supreme Court decision 29/Pid.Sus-TPK/2021/PN.Jkt.Pst the panel of judges decided that Juliari Peter Batubara must pay state compensation money. The main issues raised by the author 1) What is the process for managing returns to state finances resulting from criminal acts of corruption (Study of Supreme Court Decision 29/Pid.Sus-TPK/2021/PN.Jkt.Pst), to the state according to the applicable laws and regulations? 2) Are there any obstacles in the process of recovering state financial losses from corruption? This study uses a normative research type that is descriptive-analytical. Data collection uses primary data and secondary data. The data is processed qualitatively by drawing conclusions using a deductive method. The results of the research show that the process of managing state financial losses carried out by the defendant Juliari Peter Batubara refers to the Attorney General's Office Regulation of the Republic of Indonesia Number 19 of 2020 concerning Settlement of Compensation Money Decided by Courts and Regulation of the Minister of Finance Number 225 of 2020 concerning the Electronic State Revenue System . In the process of returning state financial losses resulting from the corruption crime of Juliari Peter Batubara there were no obstacles because the convict was able to and had compensated for the state losses arising from the proceeds of the corruption crime.
PUTUSAN BEBAS YANG TIDAK MEMPERTIMBANGKAN ALAT BUKTI DALAM PERSIDANGAN PERKARA TINDAK PIDANA
Authors: Azahra Aura , Setiyono
Published: April 2024

Acquittal Deicision is a deicision that proveis that the guilt charged to defeindant has not been provein legally and convincingly guilty. Thei probleim in this study is thei consideration of evideince in the acquittal dictum and eivideintiary poweir eiach evideince in a crimei  fileid by the public prosecutor. Based on the probleim it was found that there was a discrepancy in the consideiration of evideincei in the acquittal dictum where in fact the evideince submitteid and examineid in thei trial had met the two minimum principleis of eivideincei and fulfilleid thei two eleimeints of the articlei one hundreid eiighty  fivei seiction six of thei Criminal Procedure Code and thei streingth of the evideince submitted and examined is containeid in Article one hundreid eighty four section one of the Criminal Procedure Code. The reseiarch method used is normative juridical by conducting qualitative  data analysis.
SENGKETA STATUS SILALA ANTARA BOLIVIA DAN CHILE BERDASARKAN UNWC 1997
Authors: Balqis Devina Nuzlia , Budianto Anto Ismu
Published: April 2024

Territorial disputes are border issues between countries that often occur internationally. As happened in the relationship between Bolivia and Chile regarding the dispute over the Silala River, the use of Silala waters began in 1906. Where the two countries were involved in disputes regarding the status and use of Silala. Bolivia emphasized that the Silala spring did not meet the requirements to be considered an international waterway due to the canalization and that Chile had to pay compensation. On the other hand, Chile claims Silala as an international waterway. With these overlapping claims, Silala disputes cannot  avoided. This dispute was submitted to the International Court of Justice by Chile on June 6, 2016. This research examines the status of Silala based on UNWC 1997 and the efforts taken by the two countries in resolving the Silala waters dispute. This research is a normative legal research that was collected based on literature studies and analyzed qualitatively with deductive methods and using secondary data. From
PEMBATALAN PERKAWINAN KARENA KAWIN PAKSA MENURUT HUKUM KELUARGA ISLAM DI INDONESIA
Authors: Husen Nur Afni , Setyaningsih
Published: April 2024

The Tangerang Religious Court has decided to cancel marriage due to forced marriage with Number 2801/Pdt.G/2018/PA.Tng where the husband requests to cancel the marriage because the marriage was carried out by force. The 2 (two) main issues raised are whether forced marriages can be used as a reason for annulment of marriages based on Islamic family law in Indonesia and whether the decision of the Tangerang Religious Court is in accordance with Islamic family law in Indonesia or not. The research was conducted normatively with the nature of descriptive-analytical research and drawing conclusions using deductive logic methods. Forced marriage causes disputes in the household, so it can be a reason for filing an annulment of marriage. Tangerang Religious Court Decision No. 2801/Pdt.G.2018/PA.Tng states that the marriage annulment is granted so that, in this case, the marriage annulment has fulfilled the reasons according to the provisions of Article 71 letter (f) Compilation of Islamic Law which was caused by coercion. Thus, the decision is appropriate based on a review of Islamic family law in Indonesia.
Assessing the geological relationships between the mafic-ultramafic intrusion in the Haib area and the Vuurdood Subsuite, Richtersveld Subprovince
Authors: Jogee B.A. , Bybee G.M. , Robb L.J. , Reid D.L. , Minnaar H. , Caricchi L. , Bolhar R.
Published: April 2024

The Haib porphyry copper deposit is situated in the Richtersveld Subprovince and is host to unique Palaeoproterozoic porphyry copper mineralisation in Namibia. Several lines of evidence, including machine-learning geothermobarometry, indicate that the deposit is exposed at mid- to upper-crustal levels, as constrained from average pressure and temperature estimates of 4 kbar and 870°C, respectively. The Haib porphyry copper deposit is associated with, and is in close proximity to, a mafic-ultramafic intrusion named the Kokerboom Intrusion (KI) in this study. Together with several other mafic intrusions in this region, these intrusions are known collectively as the Vuurdood Subsuite of the Richtersveld Subprovince. The purpose of this study is to demonstrate a genetic link between the KI and the Vuurdood Subsuite using lithological characteristics, mineral and alteration assemblages, major and trace element geochemistry and U-Pb geochronology. Pyroxenites from the KI contain magmatic sulphides and have a geochemical affinity with shallow plutonic and volcanic rocks of the Haib porphyry, providing a unique mid-crustal perspective on porphyry copper deposit metallogenesis.
The petrogenesis of orbicular granites in the Diana’s Pool area, Zimbabwe
Authors: Dumisa S.S. , Bybee G.M. , Nex P.A.M. , Jogee B.A.
Published: April 2024

This paper assesses a poorly studied outcrop of orbicular granite from the Matopos granite batholith in the Diana’s Pool area, Zimbabwe. Historical samples from Diana’s Pool exhibit closely packed orbicules in a granitic matrix. They are 9 to 14 cm in diameter and are characterised by different types of orbicules containing coarse-grained felsic cores, fine-grained and alternating ferromagnesian and feldspathic shells, and a coarse-grained matrix. The orbicules are generally spherical to ellipsoidal in shape, however, some appear to be abraded and deformed. The compositions and grain sizes of cores and the matrix are comparable. Both the matrix and the cores are medium- to coarse-grained and dominated by plagioclase (the matrix probably in slightly lesser proportions), microcline (in variable proportions, and seemingly absent in some cores), quartz, biotite and accessory hornblende and magnetite. Contrary to the cores and matrix, shells are fine-grained and exhibit polygonal textures. In addition to this, the shells are dominated by biotite and magnetite; however, they do not contain hornblende. Plagioclase shows an almost complete overlap of An contents, x¯ = 26 ± 2.3 (core), x¯ = 24 ± 0.9 (shell) and x¯ = 25 ± 2.0 (matrix). Biotite composition in the shells is significantly less magnesian (x¯ = 16 ± 2.4) than in core (x¯ = 27 ± 2.2) and matrix (x¯ = 25 ± 2.2), whose compositions overlap. Average initial 87Sr/86Sr ratios from plagioclase in all the analysed shells (x¯ = 0.70226) are slightly more radiogenic than in the matrix (x¯ = 0.70193) and cores (x¯ = 0.70187). Cores are autoliths, which are plagioclase-rich, cumulate, or rim fragments reworked by new magma inputs or injections. Heterogeneous nucleation leading to the formation of orbicular shells around the cores is attributed to adiabatic decompression of magma pulses ascending in dykes, leading to superheating and resorption of early solids, and volatile exsolution, inducing undercooling, supersaturation, and shell crystallisation. The coarse-grained matrix crystallised later, after the orbicules formed, creating the groundmass and locking the orbicules in place. The deformation of shells and cores suggests that the orbicules continued to evolve in the presence of a melt (matrix material). As part of the Matopos Hills World Heritage Site, the Diana’s Pool orbicular granites present a unique and noteworthy petrogenesis, which should be preserved as part of the region’s important geoheritage.
Failure to take measures to prevent and resolve conflicts of interest: labor law issues
Authors: Basalaeva Svetlana Pavlovna
Published: April 2024

The subject of the study is the failure to take measures to prevent and resolve conflicts of interest. Failure to take measures is considered as an element of the objective side of disciplinary misconduct in labor relations, the composition of which is defined in paragraph 7.1. part 1 of Article 81 of the Labor Code of the Russian Federation, along with such elements as "conflict of interest" and "loss of trust". The types of measures are studied, the collision of their anti-corruption and labor-law nature; the subject of taking measures; the possibility of choosing a measure by an employee and an employer; the legal consequences of non-acceptance; the head as a subject of responsibility in case of non-acceptance of measures; the obligation to notify about a conflict of interests; the content of the concepts of "prevention" and "settlement". The object of the study is labor relations in terms of disciplinary responsibility for corruption offenses and related official legal relations. The author uses the general scientific method of dialectical cognition, as well as a number of private scientific methods: technical-legal, systemic-structural, formal-logical (deduction, induction, definition and division of concepts) and others. The article discusses the following problematic issues: 1) the ratio of measures provided for by anti-corruption legislation with labor law institutions, in particular, transfer to another job and suspension from work; 2) the possibility of abuse of the right by the employer and violation of the rights of the employee when taking measures; 3) the situation of legal deadlock when it is impossible to take measures; 4) unjustified inconsistency of legal regulation of measures in labor and official legal relations. The article draws conclusions about the illegality of dismissal only for failure to inform about a conflict of interest; about the priority of the employee's right to choose a measure to avoid abuse of the right by the employer; about the unification of legal regulation of suspension from work for the period of investigation of corruption misconduct or dismissal of the head for failure to take measures in labor and official relations; about ways out of the "legal impasse" if it is impossible to resolve a conflict of interest, in particular, a separate basis for termination of an employment contract due to circumstances beyond the control of the parties, or permission to act in a conflict of interest with little benefit.
Thermal Behavior of Solid Heated by Gaussian Moving Heat Source
Authors: Nguyen Minh-Nhat , Laraqi Najib , Bauzin Jean-Gabriel , Cherikh Mehdi-Belkacem , Hocine Ali , Peter Zsolt-Andrei
Published: April 2024

In this paper, an analytical development is proposed to explicitly calculate the three-dimensional and transient temperature of a solid heated by a Gaussian moving heat source. The moving source dissipates heat in a thin layer near the irradiated surface of the solid and can be constant or pulsed or have any time evolution, depending on the application. The resulting solution requires only one convergent integral over time, which can be quickly computed numerically using, for example, a commercial formal calculation software. On the other hand, the derivative of the temperature with respect to time is fully explicit. We show that the results of the developed analytical solution are in excellent agreement with those of a numerical modeling that we performed under the same conditions. The temperature evolutions and the thermal maps are presented and commented.
Advancement of firefighters in high-temperature zones
Authors:   Forensic expert Institution of the Federal Fire Service “Fire Test Laboratory” in Irkutsk region, KASHIN Aleksander N. , ISCHENKO Andrey D. ,   State Fire Academy of EMERCOM of Russia
Published: April 2024

Purpose. This article addresses the issue of the impact of hazardous fire factors (HFF) on firefighters in an environment unsuitable for breathing. Currently, there are no regulatory criteria for permissible exposure of firefighters to HFF, particularly elevated ambient temperatures. To reach the position for deploying fire extinguishing agents, firefighters are forced to traverse a zone of elevated temperatures, and in some cases, remain in it for some time. The authors have studied the effect of elevated temperatures during firefighting on the ability of smoke divers to advance towards the fire zone in personal respiratory and vision protective equipment, as well as in firefighting gear. Methods. A field experiment was conducted to assess the ability of firefighters to advance in high-temperature zones. Temperature values and corresponding sensations of firefighters were studied to identify the peculiarities of the smoke divers teams' (SDT) work when advancing in different zones of elevated temperatures. Findings. The experiment demonstrated the peculiarities of advancement of smoke divers in high-temperature zones and the limiting conditions thereof. The experiment was conducted under conditions approximating real ones, created in the “Ugolyok” training complex. The analysis conducted based on the experiment results allowed determining the range of tolerance for elevated temperatures by firefighters, depending on the protective properties of firefighting gear, their own tolerance threshold, experience working in high-temperature zones, and the use of other protective methods. For instance, at temperatures of 150–180°C, SDT were able to reach the fire zone, but they reported feeling the temperature already, making it difficult to work near the fire zone for an extended period. When the temperature rose to 280–350°C, poorly protected areas (knees and elbows in contact with firefighting gear, hands, head, and legs between the boot shin guards and liners) began to burn, making advancement difficult and unsafe for the lives and health of smoke divers at such temperature levels. Research application field. The results of the conducted experiment justify measures aimed at increasing the effectiveness of personnel work in high-temperature zones and minimizing risks during the performance of professional tasks. The results can also be used in expert examinations of firefighting organization (e.g., in determining the possibility of advancing SDT into various zones). Conclusions. The authors have more thoroughly studied the mechanism of SDT work when advancing under the influence of hazardous fire factors, describing the sensations of smoke divers under different temperature conditions. The conducted experiment allowed determining the levels of tolerance for elevated temperatures by firefighters in firefighting gear and respiratory and vision protective equipment.
On ways to strengthen emergency humanitarian response of EMERCOM of Russia outside the Russian Federation
Authors:   State Fire Academy of EMERCOM of Russia, NAMYCHKINA Elizaveta V. , SKURKO Elizaveta M. ,   State Fire Academy of EMERCOM of Russia, EVSEEV Vasily V. ,   Department of International Activities of EMERCOM of Russia
Published: April 2024

Purpose. Currently, on average, a disaster which demands international response forces for elimination is registered in the world every week. In this regard, there is an increasing need to train specialists capable of participating in international emergency response in accordance with the universal methodology developed by UNDAC. To solve this problem, it is necessary to work out an algorithm for conducting exercises and training sessions. The purpose of this article is to analyze the international exercises on coordinating and assessing emergency humanitarian response conducted in November 2023 by EMERCOM of Russia in order to work out didactically sound methodology for conducting such exercises in the long run. The relevance of the study is accounted for the demand for Russian specialists in humanitarian response at the international level, on the one hand, and the need to develop uniform algorithms for training Russian rescuers for international cooperation when responding to emergencies, on the other hand. Methods. System analysis, information synthesis methods and expert analysis methods have served as a scientific basis for the study. Findings. The analysis of the exercises effectiveness has been carried out from the point of view of implementing the assigned tasks – updating communication skills in English in the professional sphere; forming theoretical basis and developing practical skills in the field of international humanitarian response to emergencies; forming soft skills. A unified algorithm has been worked out for preparing Russian rescuers for international cooperation when responding to emergencies. Research application field. The results obtained can be used to organize similar exercises in future, which will increase the effectiveness of training international-level Russian rescuers and allow them to successfully solve professional tasks in real emergencies. Conclusions. The format of the international exercise gives its participants an opportunity to gain the necessary theoretical knowledge and practice key skills and habits in a short time. The success of the exercises allows the organizers to conclude that it is advisable to keep this format and content in future regarding all components of the exercise: language training, practical value and updating soft skills.
How the fire statistics was created
Authors:   State Fire Academy of EMERCOM of Russia, BRUSHLINSKY Nikolay N. , SOKOLOV Sergey V. ,   State Fire Academy of EMERCOM of Russia, GRIGORIEVA Margarita P. ,   State Fire Academy of EMERCOM of Russia, WAGNER Peter ,   Fire and Rescue Academy of the City of Berlin
Published: April 2024

Purpose. The article presents a brief history of the world fire statistics creation since the formation of the Center for World Fire Statistics in 1995. The article presents the results of the main indicators statistical study of the fire situation in the world for 30 years and the distribution of integral fire risks using the example of several countries (Russia, Hungary, Czech Republic, Austria, Great Britain, Poland, USA). The main objectives of the study are to review the periods of global fire statistics development, to analyze indicators characterizing the number of fires and their consequences in the world for the period from 2012 to 2021. Methods. Methods of mathematical statistics have been used. Findings. The article presents the main historical milestones in the creation of a system for recording global indicators of the situation with fires and their consequences. The results of a statistical analysis of the fire situation in the world for the period from 1993 to 2021 are summarized. The dynamics of relative indicators of the fires and death toll in fires in the above countries is presented. Research application field. The results of the study can be used by fire service specialists from around the world for a comparative analysis of the fire risk level in countries and cities. Conclusions. Over 28 years the Center for Fire Statistics (hereinafter referred to as CFS) has analyzed 104 million fires, in which 1.1 million people died. At the same time the Center annually collects statistical data from 35–40 countries and the largest cities in the world (with a delay of 2 years). In total, CFS reports have been translated into 8 languages. Since 1993 the CFS has published 28 statistical reports in the public domain. Thus, it becomes possible to analyze the fire situation in countries and cities around the world.
Systematization of statistical data on eliminating fires and emergencies occurring during a special military operation
Authors:   Academy of Civil Defense of EMERCOM of Russia, FEDOTOV Sergey B.
Published: April 2024

Purpose. The article provides systematic data on the situation with fires in the Donetsk People's Republic occurring after air and missile strikes of the armed forces of Ukraine and for other reasons in 2022 and in the first half of 2023. The main objectives of the study are as follows: systematization of daily digital indicators of hazardous events during a special military operation in Ukraine and identification of the main types and scale of fires to which fire and rescue units respond during military conflicts. The relevance of the study is accounted for the lack of systematic data on the practice of actual solving modern civil defense problems. Methods. In addition to general scientific methods of analysis and synthesis, the author used empirical methods of describing and comparing texts of the daily operational reports of EMERCOM of DPR on the composition and content of events, their digital indicators related to the real chronology of the military conflict events. Findings. The article assesses the number of fires caused by enemy ammunition strikes and other reasons. Systematized digital data for the considered period of the military conflict are summarized in a tabular form, which creates the possibility of their further scientific processing. Research application field. The outcomes of the study can be used when defining the composition and content of measures to combat fires occurring during military conflicts or resulting from them. Conclusions. The study allowed the authors to draw a number of conclusions. 1. Damage caused by fire in military conflicts must be taken into account independently – damage from attacks by enemy ammunition should be assessed separately from damage from non-military causes. 2. Means and forces of EMERCOM and other bodies are involved in eliminating consequences of emergencies and suppressing fires occurring due to military conflicts or resulting from these conflicts. 3. Statistical data on functioning the unified state system for alerting about emergencies and their elimination (RSChS) in the future must be analyzed with consideration of the data from the reports of EMERCOM of DPR, EMERCOM of LPR and the Ministry of Internal Affairs of DPR, the Ministry of Internal Affairs of LPR, considering them as valid empirical material reliable for scientific research.
Model for forming knowledge base in training fire service-technical specialists
Authors:   State Fire Academy of EMERCOM of Russia, ORLOVA Olga N. , KOLESNIKOV Vladimir V. ,   State Fire Academy of EMERCOM of Russia, RAKHMATULIN Ruslan S. ,   State Fire Academy of EMERCOM of Russia
Published: April 2024

Purpose. The article discusses and analyzes the algorithm and methodology for assessing quality of forming functions (competencies) of students in higher educational institutions of the EMERCOM of Russia (hereinafter referred to as EOHE – Educational Organization of Higher Education) on the basis of previously developed systems. Methods. The analysis of forming functions (competencies) of a future specialist is aimed at one of the highest priority tasks in the implementation of higher education programs in EOHE. Professional competencies of a specialist in real life work (service) conditions are manifested in the ability and readiness to solve assigned tasks within the framework of professional activities. Quality indications of forming functions (competencies) are the ongoing theoretical and practical development of knowledge, skills and habits, as well as their full use in work activities. It should be noted that the quality professional level of a future specialist which is the target objective of any socioeconomic system depends on the competent formation of functions (competencies), determined by the direction of training. Findings. At the moment, in order to train highly qualified specialists in the educational system of the EMERCOM of Russia, it is recommended to use a dynamic model when implementing a network form of the educational program in EOHE, which will allow optimizing system of managing educational process in higher educational institutions of the EMERCOM of Russia. Research application field. The results of the study can be used in educational institutions of EOHE, which are largely provided by the potential of the teaching staff and the logistics of organizations, which will allow achieving high levels of professionalism of future workers (employees). Conclusions. The authors propose to use the results in the organizational design of EOHE management system. The network form of implementing educational program makes it possible to train a highly qualified specialist with a wide range of knowledge in the field of fire safety, as well as in-depth knowledge within the framework of furher service.
Intense pulsed light versus pulsed dye laser in the treatment of nail psoriasis: Intra-patient left to right comparative controlled study
Authors: Morsy Eman EL , Mohamed Raneen , Omar Shaimaa Ismail
Published: April 2024

Background

Until now, the management of psoriatic nails has not been satisfactory. Pulsed dye laser (PDL) as well as intense pulsed light (IPL) have been evaluated separately for the management of psoriatic nails and proved to be effective.

Aim

This study aimed to measure and compare the usefulness as well as the safety of intense pulsed light versus pulsed dye laser for the management of psoriatic nails.

Methods

The psoriatic fingernails of 20 patients were managed using intense pulsed light on one hand and pulsed dye laser on the other. Two to three psoriatic nails were left without treatment as controls. The therapeutic sessions were conducted monthly for a period of 6 months. Evaluation of the clinical outcomes was assessed by a blinded dermatologist depending on the total, nail bed, nail matrix, modified and target NAPSI scores. Patient global assessment, in addition to Nail Psoriasis Quality of Life (NPQL10), was performed to assess the response to the therapy.

Results

A significant reduction in the total, target and modified NAPSI scores from baseline to the end of the study was detected, but no significant differences were detected between the two treatments. The responses of the nail matrix and bed lesions to both modalities were nearly the same. All patients stated that the two devices were efficient and improved their quality of life. The intense pulsed light treatment was more painful. Complete clearance of nail lesions was not obtained.

Limitations

Lack of long-term follow-up of cases and preset laser parameters were the major limitations of this study.

Conclusion

Intense pulsed light, like pulsed dye laser, is safe and efficient in treating nail psoriasis; however, the former is more painful. Dermoscopy had an additive function in analysing the response of nail psoriasis to therapy.
Pengetahuan tentang Hipertensi dan Hubungannya dengan Kepatuhan Minum Obat di Kalangan Masyarakat Hipertensi
Authors: Ghofar Abdulloh Ahmad Abdul , Yusuf Ah. , Qur'aniati Nuzul , Veriyallia Vera
Published: April 2024

Ketidakpatuhan penderita hipertensi dalam pengobatan penyakitnya berdampak pada tidak terkontrolnya tekanan darah yang dapat memperburuk status kesehatan dan bahkan kematian. Salah satu faktor penting yang harus diperhatikan dalam upaya meningkatkan kepatuhan hipertensi adalah pengetahuan penderita tentang penyakitnya dan penatalaksanaan yang diperlukan. Tujuan penelitian ini adalah untuk mengetahui hubungan pengetahuan dalam mendukung praktik kepatuhan penderita hipertensi dalam mengkonsumsi obat anti-hipertensi. Desain penelitian yang digunakan adalah analisis deskritif cross sectional. Besar sampel penelitian ini sebanyak 220 responden, direkrut melalui teknik purposive sampling. Analisis data penelitian dilakukan dengan menggunakan uji statistik chi square. Sebanyak 51,8% penderita hipertensi memiliki pengetahuan cukup dan 65,9% penderita hipertensi mengaku tidak patuh dalam meminum obat yang dianjurkan. Nilai hasil uji < α 0,05 (p= 0,000), artinya pengetahuan berhubungan signifikan dengan kepatuhan minum obat. Pengetahuan adalah komponen terpenting yang harus dimiliki penderita agar mereka dapat terlibat aktif dalam praktik kepatuhan. Diharapkan temuan ini dapat dijadikan sebagai bahan pertimbangan dalam merumuskan intervensi pengobatan bagi penderita hipertensi kaitannya dengan upaya meningkatkan kepatuhan penderita dalam hal meminum obat anti-hipertensi.
Analisis Penerapan Seiri, Seiso, Seiton, Seiketsu, Shitsuke, dan Good Manufacturing Practices Unit Blow Molding PT. X
Authors: Sabila Putri Ayu Kusuma  , Dwiyanti Endang
Published: April 2024

Industri manufaktur harus memiliki sumber daya manusia yang kompeten dan berkualitas untuk dapat menghasilkan produk yang sesuai standar sehingga perusahaan dapat mencapai keuntungan setinggi-tingginya. Perusahaan tidak hanya didukung dari infrastruktur yang memadai, tetapi juga harus didukung oleh adanya budaya kerja yang baik dan optimal. Bentuk dukungan yang diberikan adalah adanya penerapan 5S (Seiri, Seiso, Seiton, Seiketsu, Shitsuke) dan GMP (Good Manufacturing Practices). Penelitian ini bertujuan untuk menganalisis penerapan 5S dan GMP pada Unit Blow Molding di Perusahaan X. Penelitian ini merupakan penelitian deskriptif kuantitatif. Penelitian ini dilakukan secara observasional yang bertujuan untuk mengamati kondisi lingkungan kerja pada Unit Blow Molding secara langsung sesuai keadaan aktual. Lokasi penelitian berada di salah satu perusahaan manufaktur plastik yang memproduksi kemasan kosmetik. Penelitian dilakukan pada bulan Desember 2023. Pengambilan data dilakukan dengan metode observasi, wawancara, dan dokumentasi. Hasil penelitian ini menunjukkan bahwa penerapan dengan kategori “Baik” (≥ 85) diperoleh pada aspek Seiri, Seiton, Shitsuke, dan Good Manufacturing Practices. Penerapan dengan kategori “Cukup” (65-84) diperoleh pada aspek Seiso dan Seiketsu. Kesimpulan penelitian ini adalah penerapan Seiri, Seiton, Shitsuke, dan Good Manufacturing Practices sudah memenuhi target yang ditetapkan perusahaan. Saran dari penelitian ini adalah mengoptimalkan pelaksanaan audit internal, melakukan monitoring pada para operator, dan memberikan reward terhadap operator yang berhasil menerapkan 5S dan GMP dengan baik.
A Case of Multiple Embolic Strokes Caused by a Congenital Left Ventricle Diverticulum Undetected on Echocardiography
Authors:   Department of Diagnostic Imaging, Oncological Radiotherapy and Haematology, Agostino Gemelli University Polyclinic Foundation IRCCS, Rome, Italy, G Rovere , A Perazzolo ,   Department of Radiological and Haematological Sciences; Section of Radiology, Catholic University, Rome, Italy, E Moliterno ,   Department of Radiological and Haematological Sciences; Section of Radiology, Catholic University, Rome, Italy, L Giarletta ,   Department of Radiological and Haematological Sciences; Section of Radiology, Catholic University, Rome, Italy, A Brancasi ,   Department of Radiological and Haematological Sciences; Section of Radiology, Catholic University, Rome, Italy, R Marano ,   Department of Radiological and Haematological Sciences; Section of Radiology, Catholic University, Rome, Italy
Published: April 2024

Congenital Left Ventricular Diverticulum (CLVD) is a rare cardiac malformation caused by a localized protrusion of the left ventricular wall and usually diagnosed with routine echocardiography. CLVD is often associated with other cardiac and noncardiac abnormalities, but it can also occur alone. When echocardiography is non diagnostic, other noninvasive techniques such as cardiac CT (CCT) and Cardiac MR (CMR) can help to rule in/out the diagnosis by providing additional information on myocardial structure, morphology, and kinetics of both ventricles and of the diverticulum itself. We report the case of a patient who arrived in the Emergency Department for an acute cerebrovascular ischemic event with embolic pattern, who underwent non invasive diagnostic tests in order to identify the etiology.
Anesthesia Management for Asymptomatic Aortic Narrowing
Authors:   Pole Anesthésie-Réanimation Hôpital Militaire d’Instruction Mohamed V, Rabat, Morocco, Atmani Walid , Boubekri Ayoub ,   Pole Anesthésie-Réanimation Hôpital Militaire d’Instruction Mohamed V, Rabat, Morocco, Hamadat Ilyass ,   Pole Anesthésie-Réanimation Hôpital Militaire d’Instruction Mohamed V, Rabat, Morocco, Abdelhamid Jaafari ,   Pole Anesthésie-Réanimation Hôpital Militaire d’Instruction Mohamed V, Rabat, Morocco, Balkhi Hicham ,   Pole Anesthésie-Réanimation Hôpital Militaire d’Instruction Mohamed V, Rabat, Morocco, Bensghir Mustapha ,   Pole Anesthésie-Réanimation Hôpital Militaire d’Instruction Mohamed V, Rabat, Morocco
Published: April 2024

An 80-year-old patient admitted to the emergency department for a fracture of the lower extremity of the femur. The clinical examination reveals a stable patient with normal hemodynamic, respiratory, and neurological status. There are no medical history records. The pre-anesthetic evaluation is unremarkable with normal test results. The patient is transported to the operating room, and after spinal anesthesia, experiences hemodynamic instability due to a tight asymptomatic mitral stenosis observed during the clinical examination.
Rural Posting in Public Health Practices: Principles and Strategies
Authors:   Department of Community Medicine, Faculty of Clinical Sciences, Niger Delta University, Nigeria, Sawyer Wisdom Ebiye , Izah Sylvester Chibueze ,   Department of Community Medicine, Faculty of Clinical Sciences, Niger Delta University, Nigeria, Ogwu Matthew Chidozie ,   Goodnight Family Department of Sustainable Development, Appalachian State University, USA
Published: April 2024

In addressing the global challenge of rural healthcare delivery, this study highlights fundamental principles and strategies to enhance accessibility and outcomes. The study found that understanding rural communities’ socio-cultural, economic, and geographic nuances is the first step for public health specialists to adapt their methods effectively. Community engagement fosters trust and active participation, reducing health inequities. Interdisciplinary teamwork involving doctors, nurses, pharmacists, and community health workers amplifies healthcare delivery’s reach and effectiveness. Telemedicine and technology offer remote areas access to high-quality healthcare, with telemedicine, electronic health records, and mobile apps enabling consultations and information exchange. Customised health education programs empower rural communities by raising awareness and promoting prevention, reducing preventable diseases through improved health literacy. Implementable strategies include mobile clinics for remote access, rural hubs for expert consultations, and incentives to sustain a rural healthcare workforce. Collaborations between governments, businesses, and NGOs ensure comprehensive rural healthcare. Data-driven policy decisions optimise resource allocation and healthcare efficiency. A holistic approach grounded in contextual awareness, community engagement, and technological innovation is vital for rural healthcare improvement. Public health practitioners can enhance rural health outcomes by applying these concepts and strategies.
Correlation between income inequality and economic growth in Russian regions: new results based on the Granger causality test
Authors: Dorofeev M. L.
Published: April 2024

The issue of income inequality is highly relevant in scientific literature. It is caused both by the population’s pursuit of achieving an acceptable level of social justice specific to a particular society and by the property, which is often attributed to income inequality, to negatively influence economic development and growth. This article conducts an analysis of cause-and-effect relations between income inequality in the Russian regions (measured by the Gini index) and the level of gross regional product (hereinafter referred to as GRP) per capita. The primary research method employed is the Granger causality test. The research is based on data from the Federal State Statistics Service on the socio-economic development of Russian regions. Direct and reversal causality tests were performed, revealing that GRP per capita influences income inequality, but not vice versa. Moreover, the logarithm of GRP per capita exhibits a bidirectional relationship with the Gini index for Russian regions. On the basis of the obtained results, it is concluded that for effective management of the issue of regional income inequality, it is advisable to use indirect methods of financial regulation instead of the direct ones and influence income inequality through indicators of GRP per capita in Russian regions, thereby creating conditions for an increase in the standard of living and average income.
Instrumentation at the leading edge of proteomics
Authors: Peters-Clarke Trent , Coon Joshua , Riley Nicholas
Published: April 2024

The proteome, or collection of proteoforms expressed in a biological system, is dynamic and heterogeneous. As our appreciation for the complexity of the proteome has evolved, so have the technologies we use to interrogate its composition. More than three decades ago, a rapid expansion in the field of proteomics was driven by the advent of soft ionization techniques focusing on capturing protein sequence information using mass spectrometry (MS). As tools to automate peptide and protein sequencing with tandem MS (MS/MS) matured, our field recognized the limits of qualitatively cataloguing gene products. This realization drove a multi-pronged expansion of MS-centric technologies that seek to capture various aspects of proteins, including their abundance, modification states, conformation and structure, and spatiotemporal relationships. Here we review innovations in MS-based instrumentation that continue to expand our ability to survey the proteome with ever increasing sensitivity, speed, and flexibility. The march of progress in MS instrumentation has been steady over the better half of the past century, but our discussion here focuses on developments within the past five years that have ushered in an exciting era in proteomics, where MS is poised to be the dominant platform for exploring biological phenotypes in basic and translational sciences for the foreseeable future.
Cost-Informed Bayesian Reaction Optimization
Authors: Schoepfer Alexandre , Weinreich Jan , Laplaza Ruben , Waser Jerome , Corminboeuf Clemence
Published: April 2024

Bayesian optimization (BO) is an increasingly popular method for optimization and development of chemical reactions. Although effective in guiding experimental design, BO does not account for experimentation costs: testing readily available reagents under different conditions might be more cost and time-effective than synthesizing or buying additional ones. To address this issue, we present cost-informed BO (CIBO), an approach tailored for the rational planning of chemical experimentation that prioritizes the most cost-effective experiments. Reagents are used only when their anticipated improvement in reaction performance sufficiently outweighs their costs. Our algorithm tracks the available reagents, including recently acquired ones, and dynamically updates their cost during the optimization. Using literature data of Pd-catalyzed reactions, we show that CIBO reduces the cost of reaction optimization by up to 90% compared to standard BO. Our approach is compatible with any type of cost, e.g., the cost of buying equipment or compounds, waiting time, and environmental or security concerns. We believe CIBO supersedes BO in chemistry and envision applications in both traditional and self-driving laboratories for experiment planning.