bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Relationship Marketing Constructs in the Service Sector
Authors: Harun Nurul Aida , Yeo Sook Fern , Ramasamy Suganthi , Fageh Achmad
Published: October 2022

Marketing is not just developing, selling and delivering products; it is creating a long-term relationship with customers, known as relationship marketing. However, some of the constructs are redundant and overlapping. Establishing relationship marketing in the service sector will bring many advantages and a competitive edge. Variables are identified and listed using a systematic literature review approach. To finish, the process of eliminating the redundant variables and categories of the finding. This research analysis highlighted the confusion and pitfalls in relationship marketing. It should bring new insights into the suitability of the constructs consistently used in relationship marketing.
Social and Creative Hubs as the Third Places of Post-Covid Era
Authors: Abdul Kadir Syazwani , Aris Nurul Nabilah , Ginting Nurlisa
Published: October 2022

To support social activities of the post-pandemic, some social and creative hubs in Malaysia have emerged with more positive vibes that may revitalise the community. With these third places revival, there is still a lack of study on what has changed for the design of third places in response to the recent Covid-19 crisis. Therefore, this study aims to examine the design of two social and creative hubs in Kuala Lumpur based on the adaptation of Ray Oldenburg's theory of third places. The research objective is to ascertain the third places' characteristics of the case studies through on-site observation.
Neuromodulation possibilities in neurogenic lower urinary tract dysfunction
Authors: Yarin G. Yu. , Kreydin E. I. , Salyukov R. V. , Kasatonova E. V. , Astrakov S. V. , Bershadsky A. V. , Vilgelmi I. A. , Shevela A. I.
Published: October 2022

Introduction. Neuromodulation has proven itself in the treatment of patients suffering from idiopathic overactive bladder and non-obstructive urinary retention, who are resistant to conservative therapy. The possible use of the method in the population of patients with neurogenic lower urinary tract dysfunction (NLUTD) is of undoubted clinical interest.

Objective. To analyze the current possibilities and features of neuromodulation in a cohort of patients with NLUTD.

Materials and methods. Original research materials published in the PubMed, eLibrary, SciVerse (ScienceDirect), Scopus, Medline, EMBASE databases, websites of professional associations without restrictions on the date of publication were used. Sixty sources were selected for citation, with preference given to systematic reviews, meta-analyses and RCTs .

Results. In relation to NLUTD, transcranial and peripheral magnetic stimulation, intravesical electrical stimulation, tibial, pudendal electrical stimulation, and stimulation of the dorsal pudendal nerve, as well as sacral and epidural methods of neurostimulation are considered.

Conclusion. The current literature optimistically presents the experience of using neuromodulation in the NLUTD patient population with the largest evidence base for invasive sacral and tibial stimulation. The studies are based on heterogeneous populations, limited by small sample sizes with insufficient descriptive part of the degree and severity of neurological diseases, and it should be considered when forming guidelines. However, the lack of other suitable therapies and promising initial results indicate the importance of further efforts to improve the applied methods of neuromodulation. Further studies are needed with larger sample sizes, better classification of diseases, and controlled study design
Sutureless partial nephrectomy
Authors: Shkodkin S. V. , Idashkin Yu. B. , Zubaidi M. Z. A. A. , Kravets A. D. , Khuseinzoda A. F. , Askari Zh. K. , Ponomarev E. G. , Nechiporenko V. Y. , Shkodkin K. S.
Published: October 2022

Introduction. A century and a half of experience in renal surgery has shown the clinical feasibility of preserving a functioning renal parenchyma and the pathogenetic validity of nephron-sparing surgery (NSS) in renal cell carcinoma (RCC).

Objective. To analyze the available scientific publications on nephron-sparing sutureless kidney surgery or without  so-called renorrhaphy.

Materials and methods. We have searched the eLibrary, PubMed, Сochrane Library and Scopus databases without time limits. A total of 19365 publications were found in the databases, including 71 randomized controlled clinical trials, 987 reviews of which 168 were systematic and 2 were performed based on data from the Cochrane Library. This review includes publications on the sutureless NSS technique in patients with RCC; clinical cases and abstracts were excluded from the formal analysis of publications. Thus, 132 publications were selected for the analysis, which are presented in the following independently or included in previous literature reviews. The studies available for analysis were quite heterogeneous in terms of patient groups, inclusion criteria, and control points, which did not allow for a meta-analysis of the data presented.

Results. An attempt to abandon the principle of kidney suturing after partial nephrectomy was implemented using methods of hemostasis based on the action of physical factors. At the same time, the value of any one of the methods that seemed at first glance did not show obvious unequivocal advantages in the NSS, the achievement of which would unequivocally reduce the severity of the problematic issue at the present stage. Significant prerequisites for such a state of the problem should be considered the monocentric nature of most studies and relatively little experience in the application of certain methods or their combinations. In the aspect of the foregoing, it is difficult to disagree with the statement that many different methods of hemostasis used during NSS appear not only to be the result of the tireless search for new opportunities by clinicians, but also the real lack of universal technologies.

Conclusion. An analysis of the advantages and disadvantages of the final hemostasis methods during NSS in patients with localized RCC indicates that this problem has not been solved and requires further research.
Nephrostomy tube misplacement in the inferior vena cava following percutaneous nephrostomy
Authors: Guliev B. G. , Povago I. A. , Talyshinsky A. E.
Published: October 2022

Percutaneous renal interventions are characterized by bleeding and infectious complications, as well as trauma to organs located near the kidney, renal or inferior vena cava (IVC). The article presents a clinical observation of a rare complication of percutaneous nephrostomy (PCN), i.e. migration of the distal end of the nephrostomy tube into the IVC. Its timely removal followed by re-nephrostomy made it possible to avoid bleeding and restore drainage of the pyelocalyceal system. Along with this, the article presents a literature review on this condition in the eLibrary, Springer, MedLine, Embase, UpToDate databases from 2000 to 2021. The indications for PCN, the frequency and risk factors of IVC damage during percutaneous renal interventions, as well as treatment tactics were studied. After the initial evaluation of the literature, ten articles were selected for further analysis. The main risk factors associated with IVC perforation after PCN include the surgeon's lack of experience in instrumental imaging, misjudgment of the length of the nephrostomy tube, and its insertion depth, resulting in its inadequate placement. Removal of the nephrostomy tube from the IVC under radiological and ultrasound guidance or open surgery are the main methods to correct for this complication.
Lower pole obstructive megaureter of duplex kidney: an exception to the Weigert-Meyer rule
Authors: Kagantsov I. M. , Kondrateva E. A. , Karavaeva S. A. , Sukhotskaya A. A. , Saliev M. V. , Sizonov V. V.
Published: October 2022

Introduction. Anatomical features of the urinary tract in patients with duplicate kidneys are described using the Weigert-Meyer rule, since the orifice of the upper ureter has an ectopic location (inferomedial) and the orifice of the lower ureter has an orthotopic location (superolateral). However, there are rare cases of violation of this rule, complicated by obstructive megaureter, ectopic ureteral orifice, the presence of ureterocele.

Objective. To report the rare clinical case of a lower pole obstructive megaureter as a violation of the Meyer-Weigert rule in the patient with complete ureteral duplication and to describe the use of ureteroureterostomy as an effective and safe method of surgical correction of the presented anomaly.

Clinical case. We present a case of the infant (5 months old) with a lower pole obstructive megaureter. This pathology was identified through intravenous urography and voiding cystourethrography. Laparoscopic proximal end-to-side ureteroureteroanastomosis was chosen as a surgical treatment. Postoperative control intravenous urography showed the effectiveness (a reduction in the lower pole collecting system of the duplex kidney was revealed) and the safety of this method of correction.

Conclusion.  There are only several clinical cases about exceptions to the Weigert-Meyer rule reported in literature, and most of them are about adult patients. The main surgical method of treatment in such cases is heminephrectomy. To our knowledge, this is the only reported case of using ureteroureterostomy in the patient with a lower pole obstructive megaureter. This technique has shown its effectiveness and safety for restoring the patency of the urinary tract, confirmed during the control postoperative examination.
New treatment options for bladder cancer patients: based on ASCO 2022 materials and beyond
Authors: Zyatchin I. V. , Reva S. A.
Published: October 2022

Bladder cancer is the fourth most common cancer worldwide and the eighth leading cause of cancer mortality in men. The advent of new systemic therapies, including PD-1 and PD-L1 inhibitors, and advances in biomarker development have revolutionized the treatment of this disease. The current guidelines of the National Comprehensive Cancer Network (NCCN) support the inclusion of some new therapies in clinical practice. Over the past decade, many approvals for immuno-therapeutic agents have been obtained. Since bladder cancer is characterized by a high frequency of mutations, there has been a widespread introduction of medicines from the group of immune checkpoint inhibitors. All studies from this review were presented at a recent meeting of the American Society of Clinical Oncology (ASCO) and published in reputable journals.
Efficacy of focused shock-wave therapy in the treatment of chronic prostatitis / chronic pelvic pain syndrome in men
Authors: Labetov I. A. , Kovalev G. V. , Volkova O. V. , Shulgin A. S. , Shkarupa D. D.
Published: October 2022

Introduction. Chronic prostatitis / Chronic pelvic pain syndrome (CP / CPPS) is an extremely common condition for which no effective treatment has been found yet. Focused shockwave therapy (fSWT) is a safe method of physical intervention that could potentially be effective in CP / CPPS treating.

Objective. To evaluate the efficacy and quality of life of patients after treatment of CP / CPPS with fSWT.

Materials and methods. A prospective cohort study included 48 patients diagnosed with CP / CPPS. The patients attended the clinic three times a week for 4 weeks (12 sessions). Each time, patients received fSWT therapy sessions by “Chronic pelvic pain” protocol. One month after the last therapy session, the men completed the validated NIH-CPSI, IPSS, and QoL questionnaires.

Results. The mean age of the patients was 40 ± 9 years. After the course of therapy, the score of Domain I “Pain” from 10.0 ± 4.7 to 6.3 ± 1.9 (p < 0.001). At the same time, no statistically significant decrease was obtained in Domain II 'Urination' scores ((5,88 ± 2,40 vs 5,42 ± 1,64; p = 0,11). By the end of therapy for Domains III and IV, the scores had changed from 4.42 ± 0.90 and 4.04 ± 1.27 to 4.48 ± 1.01 and 3.08 ± 1.22, respectively (p < 0,001). It is noted that the mean IPSS questionnaire score showed no statistically significant change over the treatment period (17,2 ± 4,8 vs 17,8 ± 4,8; p = 0,074)). QoL changed from 4.48 ± 0.99 to 2.46 ± 1.03 (p < 0.001).

Conclusion. The study demonstrated the efficacy of fSWT as a standalone method in the treatment of CP / CPPS.
The impact of the time interval from diagnosis to radical prostatectomy on oncological outcomes in high-risk prostate cancer
Authors: Reva S. A. , Arnautov A. V. , Nosov A. K. , Berkut M. V. , Petrov S. B. , Belyaev A. M.
Published: October 2022

Introduction. To date, the impact of the time interval from diagnostic prostate biopsy to radical prostatectomy on treatment outcomes remains a topical issue.

Objective. To evaluate the effect of the timespan from diagnosis to radical treatment of prostate cancer (PCa) patients on tumor morphology and long-term oncological outcomes.

Materials and methods. A retrospective analysis of the results of treatment of patients with high-risk PCa who underwent radical prostatectomy with extended lymphadenectomy from 2001 to 2019 in three St. Petersburg clinics was performed. The influence of the time interval from prostate biopsy to radical treatment on long-term outcomes was assessed.

Results. An increase in the time interval before surgical treatment over three months did not affect the tumor morphology. Five-year biochemical relapse-free survival was 79.7%, 67.8% and 52.5% among patients with time interval from biopsy to surgical treatment less than 30 days, 30 – 90 days and more than 90 days, respectively. The time interval prior to radical treatment did not have any effect on overall and cancer-specific survival.

Conclusion. The time interval from prostate biopsy to surgical intervention, not exceeding 3 months, is the most favorable with respect to long-term outcomes.
Comparison of prognostic factors that affect the survival of patients with metachronous and synchronous metastases of renal cell carcinoma
Authors: Semenov D. V. , Orlova R. V. , Shirokorad V. I. , Kostritsky S. V. , Grigoriev S. G. , Korneva Yu. S.
Published: October 2022

Introduction. The differences in progression-free survival (PFS) and overall survival (OS) depending on the line of systemic therapy, the timing of the onset of metastases, and Heng prognostic groups in patients with metastatic renal cell carcinoma (mRCC) remain unclear. This leads to the search for new prognostic factors or their combinations, depending on the characteristics of the metastatic disease.

Objective. To identify prognostic factors affecting survival rates in patients with synchronous and metachronous renal cell carcinoma metastases.

Materials and methods. A retrospective analysis of 934 patients with mPCC treated in the period 2006 to 2020 was performed, of which 319 (34.2%) patients were assigned to the intermediate prognosis group, and 388 (41.5%) to the unfavorable prognosis group. Synchronous metastases (Smts) and metachronous metastases (Mmts) were detected in 380 (40.7%) and 554 (59.3%) patients, respectively. The clinical and morphological characteristics of the tumor were analyzed, as well as laboratory parameters. Statistical analysis was carried out using Statistica 10.0 software («StatSoft Inc.», Tulsa, OK, USA ) by constructing Kaplan-Meyer curves and survival tables, building a mathematical survival model.

Results. The 3-year and 5-year OS of Smts-patients and Mmts-patients were 40.3% and 82.5%, 18.8% and 64.3% respectively. The median OS was 25 and 88 months, respectively (p < 0.001). The 3-year and 5-year PFS rates in Mmts-patients were 60.5% and 55.7%, respectively. In Smts-patients, PFS was only 9 months, compared with a median PFS of 60 months in Mmts-patients (p < 0.001). Anemia and elevated erythrocyte sedimentation rate were observed more frequently in Smts-patients. Mmts-patients were more likely to have normal platelet and alkaline phosphatase counts. Smts-patients more often had an unfavorable prognosis according to Heng and ECOG status, a higher T stage, a low tumor differentiation, and histologically, non-clear cell carcinoma variants, the presence of lymphogenous metastases, and an increased number of organs with metastatic lesions (p < 0.001). In univariate and multivariate analyses, OS in Smts- and Mmts-patients, anemia, and poor Heng prognosis were the only statistically significant prognostic factors. In a univariate analysis of OS of Smts-patients, increases in elevated erythrocyte sedimentation platelets, and alkaline phosphatase were significant adverse prognostic factors (p < 0.001).

Conclusion. Research into new prognostic factors and their combinations, focusing on the specifics of the metastatic disease itself, will improve prediction outcomes and optimize systemic treatment outcomes.
Experimental substantiation of kidney sutures
Authors: Shkodkin S. V. , Idashkin Yu. B. , Zubaidi M. Z. A. A. , Kravets A. D. , Khuseinzoda A. F. , Askari Zh. K. , Ponomarev E. G. , Nechiporenko V. Y. , Shkodkin K. S.
Published: October 2022

Introduction. Partial nephrectomy occupies a rightful priority position in the treatment of localized renal cell carcinoma. It not only provides high oncological results but also allows you to save the renal parenchyma. This reduces the risk of chronic kidney disease and cardiovascular accidents, which is especially important in young patients. The main technical problem is the closure of the renal wound with reliable hemostasis and low risk of urine leakage, especially in patients with large endophytic lesions.

Objective. To study the mechanical properties of the renal parenchyma and to establish ways to prevent suture eruption under an experimental model.

Materials and methods. The studies were carried out using the equipment of the Center for Collective Use "Technologies and Materials of the Belgorod State National Research University". Mechanical tests of the strength characteristics of the layers of the renal parenchyma were performed on 60 cadaveric kidneys. The tensile strength and tension of tissues during the application of various surgical sutures, as well as variants of the latter with the use of spacers made of materials that prevent thread eruption, were studied using a tensile machine.

Results. During mechanical tests, the medulla was found to have the highest strength (23.58 ± 9.17 load (L)) between the layers of the renal parenchyma. The mechanical strength (8.40 ± 2.89 L) of the cortical substance in the absence of the capsule was minimal. When replacing the vertical suture through all layers by tied a knot along the resection line with a similar horizontal mattress suture, it significantly increased tensile strength (27.35 ± 12.04 L) to levels comparable to the tensile strength of the medulla. The use of a hemostatic mesh (SurgicelÒ) as a lining did not significantly affect the ultimate strength (23.58 ± 9.17 L) of the horizontal mattress suture. The use of a prolene mesh (LintexÒ mesh) for this purpose significantly prevented suture eruption (31.48 ± 9.98 L) compared to the native suture and the SurgicelÒ mesh. The maximum tensile strength (45.61 ± 6.1 L) of a horizontal mattress suture was obtained for a tape made of a polytetrafluoroethylene vascular prosthesis.

Conclusion. The study of the mechanical strength of the layers of the renal parenchyma showed the inexpediency of performing a cortical suture. The use of a horizontal mattress suture significantly increases the tensile strength compared to a vertical one. Maximum mechanical strength characteristics were obtained using polytetrafluoroethylene inserts.
Ureteroplasty using oral mucosa graft: a literature review. Update in 2022
Authors: Katibov M. I. , Bogdanov A. B. , Dovlatov Z. A.
Published: October 2022

Introduction.The review is aimed at analyzing the worldwide experience in the use of the oral mucosa in ureteroplasty due to benign ureteral strictures.

Objective.To study the features of the use of the oral mucosa in ureteral reconstruction based on a review of the worldwide literature.

Materials and methods.The review was conducted using the PubMed, EMBASE, and the Russian Science Citation Index database. In the first stage, 1013 sources were found, of which 38 articles were selected for inclusion in the review. Of these, 13 studies used an open approach, 15 — robotic, 6 — laparoscopic, 3 — laparoscopic and robotic, 1 — open and laparoscopic. A buccal graft was used in 29 studies and a lingual graft was used in 9 studies.

Results.In total, oral mucosal ureteroplasty was performed 308 times in 306 patients: open technique — 64 times, robotic — 145 times, laparoscopic — 99 times. A buccal graft was used in 67.9% (209/308) of the cases, a lingual graft was used in 32.1% (99/308). Postoperative complications were observed in 15.9% (49/308) of the cases: 12.2% after the open technique, 10.4% after the robotic technique and 20.2% after the laparoscopic technique. With a postoperative follow-up period of 1 to 85 months (average 15.3 months), treatment success was achieved in 92.5% (285/308) of the cases: 93.8% for open technique, 88.2% for robotic, 98.0% for laparoscopic.

Conclusion.The use of the oral mucosa for ureteroplasty due to benign ureteral stricture allows high rates of efficiency and safety. The results of ureteroplasty do not depend on the choice of surgical approach, type of graft and graft transplantation technique.
AKTİF ÇOK KANALLI YÜZEY DALGASI ANALİZİ (A-ÇKYDA)YÖNTEMİNDE VERİ TOPLAMA VE TABAKA PARAMETRELERİNİN TEMEL MOD DİSPERSİYON EĞRİSİ ÜZERİNDEKİ ETKİLERİ
Authors: KARSLI Hakan , ŞENKAYA Mustafa
Published: October 2022

Aktif ÇKYDA yönteminde, sığ yeraltının güvenilir bir S-dalgası hız-derinlik profilini elde etmek için en önemli aşamalarından biri, geniş frekans aralığında sürekli ve yüksek ayrımlı bir dispersiyon eğrisinin elde edilmesidir. Bu makalede, tabaka (S- ve P-dalga hızları, yoğunluk ve kalınlık) ve veri toplama (kaynak ofseti-X0, alıcı aralığı-dx ve sayısı-N, serim boyu-L=(N-1)*dx) parametrelerinin, yüzey dalga alanının temel mod dispersiyon eğrisi üzerindeki etkileri, yapay atış verilerinin analizi ile incelenmiştir. Yapay veriler, tabaka yansıma/iletim katsayısı tekniği ile hesaplanan dispersiyon eğrisi kullanılarak, her bir alıcıda harmonik mod toplama tekniği ile oluşturulmuştur. Buna göre, düşük S-dalga hızlı ara tabakalar dispersiyon eğrisinin düşük frekans bölgesinde düşük hızlara kaymasına, yüksek hızlı ara tabakalar ise, dispersiyon eğrisinin yüksek frekanslarda sürekliliğinin bozulmasına (zig-zag etkisi) ve yüksek mod etkisi yanılgısına neden olabileceği gözlenmiştir. Kaynak ofseti yüzey dalgalarının tam dalga formlarının oluşmasında etkin iken, ilk ve son alıcı arası uzaklık olan serim uzunluğunun ise, dispersiyon eğrisinin frekans bandını ve çözünürlüğünü etkilediği görülmüştür. Ayrıca, geniş alıcı aralıklarının, dispersiyon eğrisinin düşük frekans bölgesindeki güvenirliğinin arttırmasının yanında, yüksek frekans bölgesinde dalga sayısı katlanması nedeniyle dispersiyon eğrisinin sürekliliğini bozduğu görülmüştür. Sonuç olarak, farklı dalga hızlarına sahip yer modelleri için üretilen yapay veriler üzerinde yapılan analizler N
DETERMINING THE EFFECT OF LEVEL OF FLOOR, EXTERNAL WALL THICKNESS AND JACKETING ON ACOUSTIC COMFORT IN EXISTING RESIDENTIAL BUILDINGS IN TURKEY
Authors: CEVİKBAS Murat
Published: October 2022

Since people spend most of their time in the residences especially during the pandemic, acoustic comfort has come into prominence. Many studies were conducted to improve acoustic comfort. Notwithstanding the fruitful existing studies, there is no study detecting the correlation of building elements with acoustic comfort. Therefore, in this study, the correlation of floor levels, wall thickness and the availability of jacketing with the acoustic performances of existing residential buildings constructed before 2017 were investigated according to Regulation on the Protection Against Noise in Buildings entering into force on 31st May 2017 with Official Gazette. The noise levels of 155 residences in residential buildings were investigated and correlations of the level of the floor, exterior wall thicknesses and jacketing with the noise comfort were detected with the help of Pearson Correlation computed via SPSS software. It is believed that this study will improve practical implementations of existing standards in the construction industry.
GIDA SEKTÖRÜNDE YÖNETİM SİSTEMİ DENETİMLERİ VE KARŞILAŞILAN SORUNLAR
Authors: DEMİRAĞ Mustafa Kemal , HEPÇİMEN A. Zeki , ÖZEL Fırat , KEMAHLIOĞLU Ömer Kemal
Published: October 2022

Güvenli gıdaya ulaşmada en temel öğe denetimdir. Gıda fabrikaları ve tedarikçileri düzenli olarak kalite yönetimi ve gıda güvenliği kapsamlarında denetimlerden geçmektedir. Bu denetimler mevcut yasal düzenlemelerin ortaya koyduğu gerekliliklerin yanı sıra gıda güvenliği standartlarının öngördüğü konuları da içermektedir. Bu yönüyle denetimlerin içeriği, temel olarak gıda güvenliği ve gıda kalitesi konularını kapsamakla birlikte iş sağlığı güvenliği, çevre, sosyal uygunluk, dini beklentiler, gıda savunması, tarımsal üretim metotları ve özel müşteri beklentileri olabilmektedir. Ürün kalite kriterleri ve uygulamaları, uluslararası standart komisyonları, üretici ve perakendeci birlikleri, ulusal ve uluslararası zincir marketler tarafından standartlar olarak yayınlanmaktadır. Bu amaçla çıkartılan standartların hedefi gıda güvenliği ve gıda kalitesi olmaktadır. Ayrıca tüketicilerin sağlığını ve beklentilerini garanti altına almak, işletme uygulamalarından ortaya çıkabilecek riskleri de ortadan kaldırmaktır. Sektör olarak çok geniş bir yapı oluşturan gıda işletmeleri, standart uygulanmalarından çok ciddi faydalar sağlamakla birlikte, denetim uygulamaları sırasında bazı zorluklar yaşayabilmektedir. Özellikle küçük ve orta büyüklükteki işletmelerin gelişebilmeleri için doğru bilgi kaynaklarına ve maddi desteklere ihtiyaçları olduğu açıktır. Bu çalışmada standartların oluşturulma amaçları, kapsamları, üreticilerin sağladığı faydalar, uygulamalarda yaşanan sorunlar ve olası çözüm önerileri ile geleceğe ilişkin beklentiler değerlendirilmiştir.
TARIMSAL BİR ATIK OLAN HAVUÇ YAPRAĞININ BİTKİ ÇAYI OLARAK DEĞERLENDİRİLMESİ
Authors: TÜRKÖZ Beyza , BARDAKÇI Merve Seçil , BIYIKLI Ayşe , KARACABEY Erkan
Published: October 2022

Günümüzde sağlıklı ve dengeli beslenmenin öneminin artmasıyla farklı içerikli bitki çayı tüketimine olan ilgi de artmıştır. Tarımsal bir atık olan havuç yapraklarının yüksek askorbik asit içerdiği bilinmektedir. Bu sebeple havuç yapraklarının kurutularak bitki çayı formunda tüketilebilir hale getirilmesi hem tarımsal bir atığın değerlendirilmesi hem de içeriğindeki askorbik asitten faydalanılması açısından dikkat çekicidir. Bu amaçla bu çalışmada tüketilebilir formda olması amacıyla kurutulan havuç yaprakları farklı sıcaklık ve sürelerde demlenmiştir. Demlenen havuç yapraklarının askorbik asit içeriği, toplam antioksidan aktiviteleri ve toplam fenolik içerikleri tespit edilmiştir. Havuç yaprağının çay olarak değerlendirilmesinde ise infüzyon yöntemi kullanılmıştır. Farklı sıcaklık (50°C ve 70°C) ve süre (1, 4 ve 7 dakika) parametreleri kullanılarak demleme yapılmış ve elde edilen özütlerin içeriklerine bakılmıştır. Genel olarak demleme sıcaklığı ve süresi çayların biyoaktif özellikleri üzerinde etkili olmuştur. Askorbik asit içeriğinde 50°C 7 dk (sitrik asit ilaveli) demlemede en yüksek verim elde edilmiştir. Vakum kurutucuda kurutulan havuç yaprakları; 50 °C demleme süresine ve sitrik asit ilavesine bağlı olarak 0.95-18.16 mg A.A/100g KM askorbik asit, 98.20-533.11 mg GAE/100g KM fenolik madde miktarı, 47.51-233.18 mg T.E/100g KM antioksidan kapasite ve 70 °C demleme süresine ve sitrik asit ilavesine bağlı olarak 1.07-9.79 mg A.A/100g KM askorbik asit, 101.48-575.76 mg GAE/100g KM toplam fenolik madde, 75.37- 347.91 mg T.E/100g antioksidan kapasite gösterdiği belirlenmiştir. Tarımsal bir atık olan havuç yaprağının içerdiği askorbik asit, fenolik madde miktarı ve antioksidan aktivitesinden ötürü sağlıklı yaşamı destekleyecek nitelikte bir bitki çayı olarak değerlendirilmesine yönelik potansiyeli ortaya konulmuştur.
TÜRK İNŞAAT SEKTÖRÜNDE DİJİTAL DÖNÜŞÜM UYGULAMALARI ÜZERİNE BİR ARAŞTIRMA
Authors: ALADAĞ Hande
Published: October 2022

Endüstri 4.0 ve dijitalleşme bütün sektörleri etkisi altına aldığı gibi Türkiye ekonomisinde önemli bir yer tutan inşaat sektörünü de etkilemiştir. Ancak, inşaat sektörünün diğer sektörlere göre teknolojiyi kullanma ve dijital dönüşüme ayak uydurma noktasında, diğer sektörlere oranla geride kaldığı yönünde eleştiriler yapılmaktadır. Bu noktada, Türk inşaat sektöründe yer alan firmaların dijital dönüşüm uygulamalarına adaptasyonlarını etkileyen unsurların bulunması bu çalışmanın amacını oluşturmaktadır. Çalışmada sırasıyla inşaat sektöründe dijital dönüşüm kapsamında karşılaşılan kavramlar, Türk inşaat firmalarını dijital dönüşüme iten unsurlar, Türk inşaat firmalarının dijital dönüşümünü engelleyen unsurlar ile dijital dönüşümün başarı faktörleri ortaya konulmuştur. Belirlenen faktörler özelinde Türk inşaat firmalarında görev alan toplam 50 adet katılımcıya anket yapılmıştır. Elde edilen veriler “Göreceli Önem İndeksi” yöntemi ile analiz edilmiştir. Türk inşaat sektöründe Yapı Bilgi Modellemesi sıklıkla kullanılmaktayken; zenginleştirilmiş gerçeklik, blokzincir ve akıllı sözleşme gibi uygulamalar henüz sıklıkla kullanılmamaktadır. Türk inşaat firmalarının dijital dönüşüme uyum sağlama yönündeki itici unsurları etkin kalite, doküman ve iletişim yönetimi iken; sektörünün dijital dönüşümü önündeki en büyük engeller yeterli yetkin personel olmaması ve tüm paydaşlar için entegrasyon sağlanamamasıdır. Dijitalleşme etkisinin diğer sektörlere kıyasla çok düşük seviyelerde kaldığı inşaat sektörü için dijital adaptasyonun arttırılması önündeki engelleri, bu adaptasyonu hızlandıracak itici güçleri ve dijital adaptasyon için sahip olunması gereken başarı faktörlerini ortaya koyan çalışmaların sayısı oldukça azdır. Özellikle Türk inşaat sektörü özelinde belirtilen bu faktörlerin kapsamlı bir şekilde analiz edilmesi çalışmanın önemli bir özgün yönünü oluşturmaktadır.
STRUCTURAL FLOOD ANALYSIS BASED ON THE HYDRAULIC MODEL OF THE KÜÇÜK AKSU RIVER
Authors: BAYKAL Tahsin , TERZİ Özlem , ŞENER Erhan
Published: October 2022

In this study, flood risk areas were determined with Hec-RAS hydraulic model for the Küçük Aksu River in Antalya, Turkey. Firstly, Hec-RAS models were developed according to different recurrence flow rates and, flood propagation maps and flood depth maps were generated. As a result of the model that was developed by using a 100-year flood recurrence flow rate, it was seen that 6.04 ha of the residential area and 33.73 ha of the agricultural area is submerged. The maximum water level was determined as 11.60 m according to the 100-year flood recurrence flow rate. Then, structural flood analysis was performed using the depth-damage graph for the Küçük Aksu River. As a result of this analysis, it was seen that the economic loss caused by floods was between 1.152 million-1.946 million TL.
ANTALYA VE ISPARTA YAĞIŞ VERİLERİNİN TREND ANALİZİ
Authors: KIR Elif Gülen , GÜLDAL Veysel
Published: October 2022

Küresel iklim değişikliği, mevcut su kaynaklarında ve yağışlarda önemli farklılıklara sebep olmaktadır. Su kaynaklarının geleceğe yönelik olarak yapılan çeşitli tahminleri, sürdürülebilirlik açısından bir gerekliliktir. Bu nedenle, su kaynaklarının asıl kaynağı olan yağışların tahmin edilmesi ya da trendlerinin belirlenmesi önemlidir. Bu çalışma, Antalya ve Isparta illerinde 1971-2018 tarihlerinde kaydedilmiş aylık ve yıllık yağışların trendlerini araştırmaktadır. Analizlerde göz önüne alınan trend hesaplama yaklaşımları Mann-Kendall Trend Analizi, Sen’in Trend Eğimi Tahmincisi ve Şen’in Yenilikçi Trend Analizi yöntemleridir. Parametrik olmayan Mann-Kendall yöntemine göre Antalya ve Isparta’da kaydedilen aylık ve yıllık yağışlarda bir trend belirlenmemiştir. Sen’in Trend Eğimi Tahmincisi ile Şen’in Yenilikçi Trend Analizi yöntemlerine göre ise hem aylık ve hem de yıllık yağışlarda farklı artan ve azalan trendler belirlenmiştir. Bir sonuç olarak, her 3 yöntemin de farklı trendler ortaya çıkardığı elde edilmiştir. Şen’in Yenilikçi Trend Analizi yönteminin göz önüne alınan zaman serisini 2 eşit alt seriye bölerek elde edilebilen bir saçılmanın görsel olarak görülebilmesi açısından önemli olduğu düşünülmektedir.
GÖRÜNTÜ STEGANOGRAFİSİNDE YAYGIN KULLANILAN VERİ GİZLEME TEKNİKLERİNİN İNCELENMESİ
Authors: UZUN Murat , SOLAK Serdar
Published: October 2022

Sayısal veri iletiminde, veri güvenliğinin sağlanması için kullanılan yöntemlerden biri Steganografidir. Steganografinin amacı, verileri güvenli olmayan iletim kanalı üzerinden güvenli bir şekilde alıcıya iletmektir. Sayısal steganografinin bir alt dalı olan görüntü Steganografisi, özellikle veri gizleme kapasitesinin yüksekliği sebebiyle daha yaygın kullanılmaktadır. Makalede, uzaysal etki alanında yaygın kullanılan görüntü steganografisi tekniklerinden En Düşük Anlamlı Bit, Piksel Değeri Farkı, Değişim Yönünü Kullanma ve Genelleştirilmiş Değişim Yönünü Kullanma algoritmaları incelenmiştir. Bu yöntemler, bilgi taşıma kapasitesi, Tepe Sinyal Gürültü Oranı, Yapısal Benzerlik Endeksi gibi görüntü kalitesini ölçmek için kullanılan parametrelerin yanı sıra, histogram ve RS analizi ataklarına karşı dayanıklılık testleri incelenmiştir. Makale kapsamında gerçekleştirilen deneysel çalışmalara göre, kullanılan bu yöntemlerin birbirlerine göre üstün ve zayıf yönleri ortaya konularak, kullanım amacına göre uygun yöntem seçimiyle ilgili tavsiyelerde bulunulmaktadır. Özellikle yüksek kapasite gerektiren ve algılanamazlığın önemsenmediği durumlarda LSB-3 bit yöntemi, güvenliğin ve algılanamazlığın ön plana çıktığı daha düşük kapasitede veri gizleme işlemlerinde PVD, EMD ve GEMD yöntemlerinin kullanılması uygundur.
ANALYSIS OF DATA SECURITY AND CYBER-ATTACK METHODS IN DIGITAL CURRENCY
Authors: AVCI İsa
Published: October 2022

With the rapid development of technology in recent years, digital data in information technology has become an indispensable area of life. The use of digital data services in our daily lives has become inevitable. Money transactions, purchases, and money transfers are made by banks and users every day. With the transition from paper systems to digital systems, the number of users is increasing day by day, but there are security concerns about these systems. In modern technologies, the possibility of information theft, the risk of cyber-attack, and the fear of breaches are constantly being worried about financial losses. Since such digital currency transactions carry the personal data and privacy of users, everyone needs to complete the correct transactions reliably. Due to the great importance of financial transactions and digital currencies in daily life, this article explains the features of digital currency and how to prevent counterfeiting. It will also analyze what tools are safe to use in a cryptocurrency. The risks that the algorithm mechanisms used in these processes can handle are examined and security problems are explained. In addition, security methods, algorithms, digital currency cyber-attack methods, and security measures of crypto money are examined.
DEVELOPMENT OF MULTICARRIER VISIBLE LIGHT COMMUNICATION SYSTEM USING ARM CORTEX-M3 MICROCONTROLLER
Authors: ARIOĞLU Özhan , GURKAN Koray
Published: October 2022

With the development of technology, the constraints and the needs in the field of communication have increased. Especially, limited and licensed radio frequencies that can cause electromagnetic interference and health problems in the use of wireless communication make the visible light communication (VLC) technologies very important. In this study, an ARM based VLC system design has been realized to implement a unique product with the use of low-cost and commercial off-the-shelf electronic components. In this context, receiver and transmitter circuits are designed, printed circuit boards and appropriate enclosures have been produced, as a result, a system prototype has been created to use in interior applications with standard ceiling height. The design is also one of the few implementations in which orthogonal frequency division multiplexing (OFDM) modulation and digital signal processing applications are performed by using ARM based microcontroller. Consequently, the system communication is achieved at a data rate of 3.5 kbps from a distance 1.8 m to 3 m. Also the system communication is successfully performed from the center of the light source up to 85 cm distance on the direct side and up to an angle of 50° on the azimuth.
MONTHLY STREAM FLOWS ESTIMATION IN THE KARASU RIVER OF EUPHRATES BASIN WITH ARTIFICIAL NEURAL NETWORKS APPROACH
Authors: KATİPOĞLU Okan Mert
Published: October 2022

This study aims to estimate streamflow values with artificial neural networks (ANN) using various meteorological parameters. In developing the ANN model, various combinations of precipitation, air temperatures, and potential evapotranspiration values were used as inputs, and streamflow values were obtained. Meteorological data is divided into 70% train, 15% test, and 15% validation. In the model's design, various training algorithms, network architecture, input combinations, and the number of iterations were tried, and the most suitable model was tested. Correlation coefficient (R), coefficient of determination (R2), absolute error (AE), and absolute relative error (ARE) coefficients were compared, and the most suitable model was selected. According to the analysis results, the optimal model was obtained using 2000 iterations, the architecture of the 4-4-1 model, and the Quasi-Newton algorithm. It was determined that the ANNs successfully modeled the rainfall-runoff relationship and produced reliable estimates. In addition, it was revealed that the inclusion of potential evapotranspiration values obtained by the Thornthwaite method into the model increases the model's success.
TÜRK TEKSTİL VE HAZIR GİYİM İŞLETMELERİNDE DÖNGÜSEL EKONOMİYE GEÇİŞ-KISA BİR DEĞERLENDİRME
Authors: ALTUN KURTOĞLU Sule
Published: October 2022

Döngüsel ekonomi bir süredir, diğer sektörlerde olduğu gibi tekstil sektöründe de önemli bir gündem haline gelmiştir. Özellikle Avrupa Birliği’nin ısrarla takip ettiği ve hızlı bir geçiş planı uyguladığı döngüsel ekonomi konusunda küresel ölçekli tekstil firmaları da önemli adımlar atmaya başlamıştır. Ancak bu konuda en önemli problemlerden biri döngüsel ekonomi kavramının doğru anlaşılamamasıdır. Bu çalışmada, sektörün bu alanda şimdiye kadar en önemli kılavuzu olan ve Ellen Macarthur Foundation tarafından 2017 yılında yayımlanan rapor temel alınarak ve bu raporda yer alan prensipler kullanılarak, Türkiye’de tekstil sektörünün döngüsel ekonomiye geçişte avantaj ve dezavantajları kısaca değerlendirilmiş ve öneriler sunulmuştur. Özellikle dijitalleşme, hammadde üretme (örneğin yeni nesil liflerin üretilmesi), katma değeri yüksek geri dönüştürülmüş ürün üretme ve malzeme kullanım ömrünü uzatma konularında önemli eksiklikler göze çarpmaktadır. İç piyasaya yönelik üretim yapan firmalarda yasaklı/kısıtlı kimyasal kullanımından henüz çıkılmaması da söz konusu geçişte önemli bir engeldir. Tekstil sektörünün güçlü alt yapısı, nitelikli işgücü ve geri kazanım kapasitesi ise geçişi kolaylaştıracak üstünlükler olarak öne çıkmaktadır. Geçişi hızlandıracak temel itici güç ise ar-ge çalışmalarının ve tekstil üreticileri, geri kazanım firmaları ve araştırma kurumları arasındaki iş birliğinin artırılmasıdır.
Determinants of e-Mental Health Use During COVID-19: Cross-sectional Canadian Study
Authors: Yu Ellie , Xu Bowen , Sequeira Lydia
Published: October 2022

Background

Access to mental health treatment across Canada remains a challenge, with many reporting unmet care needs. National and provincial e-Mental health (eMH) programs have been developed over the past decade across Canada, with many more emerging during COVID-19 in an attempt to reduce barriers related to geography, isolation, transportation, physical disability, and availability.

Objective

The aim of this study was to identify factors associated with the utilization of eMH services across Canada during the COVID-19 pandemic using Andersen and Newman’s framework of health service utilization.

Methods

This study used data gathered from the 2021 Canadian Digital Health Survey, a cross-sectional, web-based survey of 12,052 Canadians aged 16 years and older with internet access. Bivariate associations between the use of eMH services and health service utilization factors (predisposing, enabling, illness level) of survey respondents were assessed using χ2 tests for categorical variables and t tests for the continuous variable. Logistic regression was used to predict the probability of using eMH services given the respondents’ predisposing, enabling, and illness-level factors while adjusting for respondents’ age and gender.

Results

The proportion of eMH service users among survey respondents was small (883/12,052, 7.33%). Results from the logistic regression suggest that users of eMH services were likely to be those with regular family physician access (odds ratio [OR] 1.57, P=.02), living in nonrural communities (OR 1.08, P<.001), having undergraduate (OR 1.40, P=.001) or postgraduate (OR 1.48, P=.003) education, and being eHealth literate (OR 1.05, P<.001). Those with lower eMH usage were less likely to speak English at home (OR 0.06, P<.001).

Conclusions

Our study provides empirical evidence on the impact of individual health utilization factors on the use of eMH among Canadians during the COVID-19 pandemic. Given the opportunities and promise of eMH services in increasing access to care, future digital interventions should both tailor themselves toward users of these services and consider awareness campaigns to reach nonusers. Future research should also focus on understanding the reasons behind the use and nonuse of eMH services.
Group Telegaming Through Immersive Virtual Reality to Improve Mental Health Among Adolescents With Physical Disabilities: Pre- and Posttrial Protocol
Authors: Lai Byron , Davis Drew , Young Raven , Swanson-Kimani Erin , Wozow Cynthia , Chaviano Kelli , Rimmer James H
Published: October 2022

Background

Adolescents with physical disabilities have higher rates of mental health conditions and issues than adolescents without disabilities, and this disparity was exacerbated by the onset of the COVID-19 pandemic. They also have limited access to on-site programs and nearby peers.

Objective

This pilot aims to investigate the potential effects of a low-dose multiplayer virtual reality telegaming program on depression, socialization, and loneliness among a cohort of children with physical disabilities. A secondary aim is to describe feasibility metrics, namely, recruitment and adherence rates and perceived program enjoyment and satisfaction. The tertiary aim is to describe behavioral mechanisms that affect participant adherence and social participation in the classes.

Methods

This study is a single-group pre- and posttest–designed trial. A single cohort of 12 children with physical disabilities will pilot a 1-month program that includes 2 supervised 1-hour sessions per week of group-based exergaming. Participants will complete questionnaires before and after the program. The primary aim measures will include the Children’s Depression Inventory 2 Short Form, a measure of feelings of depression, and the UCLA Loneliness Scale, a measure of both loneliness and social isolation. Secondary aim measures will include three posttest Likert scale questionnaires: perceived program enjoyment, program satisfaction, and satisfaction with multiplayer experiences. At postintervention or dropout, participants will undergo semistructured interviews to identify behavioral mechanisms that underlie participation. Data will be reported descriptively and be supported by t tests as appropriate.

Results

Recruitment procedures started in July 2022. All data are expected to be collected by January 2023. Full trial results are expected to be published by March 2023. Secondary analyses of data will be subsequently published.

Conclusions

This trial tests a peer-to-peer virtual reality telegaming program that includes a completely remote enrollment, assessment, and intervention protocol. This program is accessible and short in duration and frequency, allowing it to be integrated into other interventions. Knowledge obtained from this study will inform the development of a larger trial for improving the mental health and well-being of adolescents with physical disabilities.

Trial Registration

ClinicalTrials.gov NCT05259462; https://clinicaltrials.gov/ct2/show/NCT05259462

International Registered Report Identifier (IRRID)

PRR1-10.2196/42651
The Challenges of Interdisciplinarity in Graduate Graduation
Authors: Oliveira Luciana Souza de , Oliveira Lucia Marisy Souza Ribeiro de , Santos Júlio Jose Torres dos , Aquino Andrea Araújo de , Ribeiro Andrea Reis de Souza , Souza Valmir Nogueira de
Published: October 2022

This article aims to raise discussions about interdisciplinarity, particularly in teacher education, in order to present a critical view of the need to develop interdisciplinary actions present in theoretical references and in official normative documents consulted that dialogue with the topic today. Through a bibliographic review, the importance of interdisciplinary training for teachers was brought to light, with the aim of deepening the different types of knowledge in higher education, more specifically in postgraduate courses in public universities, based on the assumption that interdisciplinarity is a concept under construction. The analytical approach of the information collected was qualitative and content analysis was used to interpret the speeches.
Epidural dexamethasone showed a better analgesic profile over epidural betamethasone as adjuvant in acute neuropathic lumbar pain
Authors: T Kitayama Antonio , Oliveira Celia S , Moraes Natalia V de , R Lauretti Claudia , A. Defino Helton , R. Lauretti Gabriela
Published: October 2022

Background: The study was designed to evaluate dexamethasone and betamethasone as adjuvants in epidural management of acute radicular pain related to pain, ocular pressure, weight gain and systemic effects. Methods: Twenty six patients with neuropathic pain secondary to disc herniation acted as their own control related to the epidural administration of dexamethasone and betamethasone. Thirteen patients have started with dexamethasone during the first two weekly procedures, and after 3 weeks of wash-out were submitted to two weekly sequences of sacral betamethasone and cross-over. Patients were evaluated related to analgesia, blood pressure, ocular pressure, weight gain, adverse effects and plasmatic measurements of ions, glycemia, ACTH and cortisol. Results: Dexamethasone was superior to betamethasone analgesia (p<0.05). Plasma cortisol and ACTH reduced on the 7th day after the block (p<0.001). The plasmatic concentrations of the ions Na+, K+, Ca++, control and post-prandial glycemia, blood pressure, weight were similar between groups and did no differ from initial control values (p>0.05). Three patients that received dexamethasone after the firs block and 2 that received betamethasone had cortisone glaucoma on day-7 (p<0.001). Discussion: Epidural dexamethasone/lidocaine analgesia was superior to betamethasone/lidocaine analgesia and both drugs resulted in similar unaware increase in ocular pressure and sleep disturbance.