bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of the efficiency of the organization of the process of preparing and submitting of integrated report
Authors: Tarasenko Oleksandr , Ionin Yevhen , Tarasenko Liliia
Published: September 2024

Introduction. The article is devoted to the analysis of the current state of organization of the process of preparing and submitting integrated report on personal income tax and unified social contribution using the approaches laid down in the lean concept. A map of the process of preparing and submitting consolidated financial statements is constructed. The map is represented by a sequence of actions in the process, indicating the duration and quality metrics of each of them. The prepared process map is used as a basis for assessing the effectiveness of the process, identifying losses in the process and developing recommendations for improving the process.
Purpose. The purpose of the article is to determine the level of efficiency of the process of preparation and submission of integrated report on personal income tax and single social contribution and to develop, on this basis, proposals for improving the efficiency of the process.
Methodology. The study was conducted using general scientific methods. The modeling method was used to prepare the business process map. The conclusions prepared on the basis of the model in the form of a business process map and the directions for improving the process were formulated using the methods of analysis and synthesis.
Results. The analysis of the current state of the process of preparation and submission of integrated report on personal income tax and single social contribution was carried out. The level of value of the process actions is identified using the tools and approaches of the lean methodology. Ways to eliminate waste in the process are proposed. The developed recommendations can be considered by enterprises for implementation in practice in order to improve the efficiency of the organization of the accounting process.
Randomized Controlled Trial: Effectiveness of Ankle Support in Reducing Ankle Sprain Pain in Futsal Players
Authors: Ningsih Cica Tri Mandasari , Septiani Anissa Eka
Published: September 2024

Background: Many people worldwide engage in sports as a hobby, for health training, work, fitness, and relaxation. However, physical activity can also lead to injuries, as can workplace accidents, traffic incidents, and mishaps at home. One common injury is an ankle sprain, particularly prevalent among highly active individuals. Several treatments are available for ankle injuries, with conservative early intervention being the preferred approach. The RICE method (Rest, Ice, Compression, and Elevation) is commonly employed initially, which can be supplemented with protection and rehabilitation to form the PRICE regimen. Protection involves immobilization, which aids in pain and swelling reduction. Additionally, medications play a role in alleviating pain and swelling. Following conservative treatment, functional intervention utilizing external support is often employed to enhance ankle joint function and stability. In cases where conservative measures fail to yield satisfactory results, surgical intervention may be necessary to improve joint stability. Aims: This study aims to assess the effectiveness of ankle support in alleviating pain among futsal players who have sustained ankle sprains. Methods: The research adopts an experimental design, specifically a randomized controlled trial (RCT), employing simple randomization to form two groups: the control group and the treatment group. Results: Non-parametric tests utilizing the Mann-Whitney Test yielded a probability value of 0.693 (> 0.05), leading to the rejection of the hypothesis. Conclusion: Consequently, the study's findings indicate no significant difference in pain reduction between futsal players who use ankle support and those who do not follow ankle sprains.
TO ASSESS THE PATTERN AND FREQUENCY OF LUNG DISEASES IN PATIENTS DIAGNOSED WITH UVEITIS
Authors: Singh Jaskirat , Kaur Avleen
Published: September 2024

Uveitis describes a group of intraocular inflammatory disorders affecting a part or whole of the iris, ciliary body, and
choroid that may be related to infective or non-infective etiological factors.It may affect other tissues in the eye as well
which includes the retina (uveoretinitis), retinal blood vessels (retinal vasculitis), the vitreous (vitritis), and the optic
nerve (papillitis)and is the third leading cause of preventable blindness globally. Uveitis may be a reflection of other
systemic diseases as well and may be the first manifestation of such systemic diseases.The present observational study
was conducted in a tertiary care teaching hospital in north India over six months.The details regarding clinical findings
and demographic data were recorded in a structured proforma.General physical examination,examination of the chest
with special attention to rule out any lesion of lungs, and other laboratory and radiological investigations which were
essential for aetiological diagnosis and treatment were performed. Statistical analysis was performed using a software
package of statistical analysis (SPSS for Windows, version 19, Armonk, NY: IBM Corp).We found in our study that the
majority (50.0%) of the patients were in the age group of 31-50 years,with 77% of patients being males.66.6% of cases
were diagnosed with Chronic Uveitis including those with recurrent attacks,and the remaining 33.3% had Acute Uveitis.
The cases were further divided into Anterior Uveitis, Posterior Uveitis, and Pan Uveitis. Mantoux skin test was also
advocated.It was observed that out total patients,20.0% of patients had an induration of +15mm on the Mantoux test.The
current study concluded that several factors,including the patient's age, other related systemic conditions, and overall
health,can affect the pattern of uveitis.
HEMANGIOPERICYTOMA OF TONGUE: A RARE CASE REPORT
Authors: Korulkar Pranav , Shinde Rajendra , Mankar Hrushikesh
Published: September 2024

Background: Hemangiopericytoma (HPC), described by Stout and Murray (1942), is a rare spindle cell tumor of
mesenchymal origin with an incidence of about 0.06% per 100,000 population, affecting both genders equally. HPC
typically develops in deep soft tissues, especially in the extremities, with only 16-25% of cases reported in the head-neck
region, commonly affecting middle-aged individuals. A 49-year-old male presented with a painless sw Case: elling in
the tongue for two years. Intraoral examination revealed a large mass occupying the mouth. MRI suggested differential
diagnoses of schwannoma or hemangioma. The mass was excised, and histopathologic examination confirmed a benign
vascular neoplasm, diagnosing it as Hemangiopericytoma. Hemangiopericytoma is a rare vascular tumor Conclusion:
with high recurrence and malignant potential, requiring awareness and long-term follow-up for effective management.
Documenting such cases is crucial to increase awareness and improve understanding.
O PAPEL DO PERITO AMBIENTAL E SEUS ATOS NO CONTEXTO DE PROCESSOS JUDICIAIS ENVOLVENDO QUESTÕES AMBIENTAIS
Authors: Sousa Maria José Rodrigues de , Guedes Gleidimar da Silva , Alves Tanizi Barroso de Moura , Pereira Cássio Luz , Praxedes Carine Fernandes , Sousa Fabrício Bezerra Alves de
Published: September 2024

Este artigo científico tem como objetivo, analisar o papel do perito ambiental e seus atos no contexto de processos judiciais envolvendo questões ambientais. O tema em análise foi escolhido através de atividades acadêmicas propostas em sala de aula sobre os sujeitos processuais, complementada com uma visita orientada a um perito ambiental judicial, onde foi possível verificar a importância e a necessidade do especialista nos processos envolvendo danos ambientais, apresentando assim a seguinte problemática: qual o papel do perito ambiental nos processos judiciais envolvendo questões ambientais? A metodologia utilizada se caracterizou por uma abordagem hipotético-dedutivo do tipo qualitativa exploratória, descritiva, documental e, que se baseia em uma revisão bibliográfica. Essa revisão foi conduzida por meio da identificação de fontes publicadas digitalmente ou em papel, tais como livros, documentos, artigos acadêmicos, dissertações, teses, sites oficiais de entidades governamentais ou não governamentais e leis. Os resultados deste estudo demonstraram que o perito ambiental desempenha um papel crucial nos processos judiciais envolvendo questões ambientais. Sua atuação se revela fundamental na busca pela verdade dos fatos, na preservação do meio ambiente, e na aplicação justa das leis ambientais. A expertise técnica desses profissionais não apenas esclarece questões complexas, mas também contribui para a proteção dos ecossistemas e a garantia da imparcialidade nas avaliações.
Dengue: Apontamentos históricos, epidemia no Distrito Federal (DF) em 2024 e imunização com a vacina Qdenga®
Authors: Benito Linconl Agudo Oliveira , Benito Rosana da Cruz , Silva Isabel Cristina Rodrigues da , Azevedo Helder Lima Garcia
Published: September 2024

A dengue (CID-11: 1959883044) se constitui enquanto uma doença febril, arbovirótica, transmissível, de notificação compulsória, aguda, além de um complexo problema de saúde pública em mais de cento e dez (110) nações, que possuem o seu clima tropical ou subtropical. O vírus da dengue (DENV) se classifica enquanto RNA, além de arbovírus da família “Flaviviridae” e do gênero “Flavivírus”, sendo que ele possuidor quatro (04) tipos imunológicos, sendo eles o dengue vírus 1 (DEN-1), o dengue vírus 2 (DEN-2), o dengue vírus 3 (DEN-3) e o dengue vírus 4 (DEN-4).
Digital transformation of the scientific and technical information management system in Chinese universities
Authors: Zhiliang Guo
Published: September 2024

The importance of scientific and technical information management in Chinese universities as a resource base for generating innovations and extracting new knowledge is proven. A conceptual model of digital transformation and factors influencing its successful implementation, including: digital management, digital services, and digital innovations, is proposed. Organizational, technical-technological and resource factors are mentioned among the factors influencing digital transformation, the importance of providing administrative, financial, personnel, technical-technological and security support for the digitalization of the communication infrastructure of Chinese universities is emphasized. A system of countermeasures and proposals, including political support and technical training, data exchange and network security, as well as standards and talents cultivation, aimed at improving the level of scientific and technical information management of Chinese universities, and the growth of their research and innovation potential, is justified.
A modern approach to the creation and integration of library digital information resources
Authors: Reznichenko Valerii , Proskudina Galyna , Kudim Kuzma
Published: September 2024

The paper presents an overview of the software and functionalities of the Scientific Digital Library of Periodicals of the National Academy of Sciences of Ukraine. It also considers the issues of integration of library systems into unified user service systems on the example of modern global aggregators of open access documents BASE, OpenAIRE and CORE. Their quantitative characteristics, such as the number of collected document descriptions and full texts, the number of data providers, and the availability of an application programming interface for data retrieval are analyzed. The composition and types of their data providers, such as institutional repositories, open journals, publishing houses, scientific repositories of preprints, thematic digital libraries, and systems that are also aggregators, are considered. We also investigated what kind of information about documents these aggregators collect and how it is presented in the user interface, as well as what information is collected about data providers and how it is presented in the user interface. How the aggregator interacts with data providers, what data exchange protocols are supported, and how the collected data is updated. The article provides a list of useful services for researchers that can be provided by modern aggregators based on collected data corpora, using machine learning methods, bibliometrics, webometrics, altmetrics, and semantometrics. As developers of a number of open access scientific digital libraries, we are already registered as data providers in these systems. At present, work is underway to create an aggregator of scientific resources of the National Academy of Sciences of Ukraine, so studying the world experience is a necessary step to solve this problem at the proper level.
DESAFIOS E OPORTUNIDADES NA SAÚDE PÚBLICA EM REGIÕES RURAIS: AVALIAÇÃO DOS OBSTÁCULOS ENFRENTADOS
Authors: Melo Ana Beatriz Oliveira de , Nascimento Maria Eduarda Bezerra do , Aguiar Priscila Silva , Esteves Ryan Farias , Oliveira Jullia Martins de , Façanha Eliomara Brito , Siqueira Helainy de Souza , Cavalcanti Ana Luiza Batista , Campanate Acsa Lia , Silva Bárbara Tatiany de Moraes , Lima Vanessa de Sousa Leal , Vieira Luma de Souza
Published: September 2024

Introdução: A saúde pública em regiões rurais enfrenta uma série de desafios que impactam diretamente o acesso e a qualidade dos serviços oferecidos. Esses desafios incluem a escassez de profissionais de saúde, infraestrutura inadequada, distâncias geográficas, além de barreiras socioeconômicas e culturais. Por outro lado, as regiões rurais também oferecem oportunidades únicas, como o fortalecimento de redes comunitárias, iniciativas de saúde local e a adaptação de estratégias de atendimento voltadas para as especificidades dessas populações. Objetivo: Identificar e avaliar os principais obstáculos enfrentados pelos serviços de saúde pública em regiões rurais. Metodologia: A pesquisa foi realizada através do acesso online nas bases de dados National Library of Medicine (MEDLINE), Scientific Electronic Library Online (SCIELO), literatura latino-americana e do Caribe em Ciências da Saúde (LILACS) no mês de agosto de 2024. Resultados e Discussão: Os resultados deste estudo indicam que os principais desafios enfrentados pela saúde pública em regiões rurais incluem a escassez de profissionais qualificados, dificuldades de transporte e acesso, além de limitações na infraestrutura. No entanto, foram identificadas oportunidades de fortalecimento por meio de estratégias como a telemedicina, parcerias comunitárias e a capacitação local de agentes de saúde. A discussão sugere que, apesar das barreiras, políticas de saúde adaptadas à realidade rural, aliadas ao uso de novas tecnologias, podem melhorar significativamente o atendimento e promover maior equidade no acesso aos serviços. Considerações Finais: Em síntese, embora as regiões rurais enfrentem desafios significativos na saúde pública, como a falta de infraestrutura e profissionais, há oportunidades promissoras para superar essas barreiras. O investimento em telemedicina, capacitação local e políticas de saúde específicas para essas áreas pode melhorar o acesso e a qualidade dos serviços, promovendo uma saúde mais equitativa e sustentável.
ANÁLISE EPIDEMIOLÓGICA DAS INTERNAÇÕES POR TRAUMATISMO INTRACRANIANO NO BRASIL, ENTRE 2019 E 2023
Authors: Sobral Sofia Bezerra , Travassos Valéria Sampaio , Lima Amanda Cristina Araujo , Da Cunha Bruna , Pereira Giullia Dutra Soares , Dos Reis Larissa Moreira , Kato Ana Beatriz Doufem , E Souza Ana Clara Freitas , Oliveira Larissa Albuquerque , Fróes Carlos César Freire , Carvalho Daniela Diniz Simões de Medeiros , Cordeiro Maria Luiza Monteiro , Chan Elvis Lucas Rabelo Shintay , De Oliveira Maria Ricarda Costa , De Oliveira George Huemerson Aramaio Barbosa , Da Cunha Lucas Fontana Breguez , Araruna Pedro Nogueira
Published: September 2024

INTRODUÇÃO: O traumatismo intracraniano (TIC) é uma lesão cerebral resultante de impactos externos ao crânio, que podem variar de concussões leves a hemorragias graves. Essas lesões podem causar danos neurológicos significativos, afetando a função cognitiva e motora. O tratamento do TIC varia conforme a gravidade e pode envolver desde monitoramento e repouso até cirurgia e reabilitação intensiva. A análise de TIC é crucial para otimizar estratégias de prevenção e gestão de saúde. OBJETIVO: Este estudo visa quantificar e analisar as taxas de internações por traumatismo intracraniano no Brasil. METODOLOGIA: O estudo retrospectivo com abordagem quantitativa utilizou dados do Sistema de Informações Hospitalares do SUS (SIH/SUS), fornecidos pelo Departamento de Informática do SUS (TABNET/DATASUS). A análise abrangeu internações por traumatismo intracraniano no Brasil de janeiro de 2019 a dezembro de 2023, empregando estatística descritiva e tabulação em planilhas do Microsoft Excel 2016 e Microsoft Word 10. RESULTADOS E DISCUSSÃO: Os resultados deste estudo revelam um total de 88.176 internações por neoplasia maligna do esôfago no Brasil entre 2019 e 2023, com a maior concentração na Região Sudeste (39.654 casos), seguida pelas regiões Sul (24.677) e Nordeste (15.718). Observa-se uma leve queda nas internações durante 2020 e 2021, possivelmente relacionada ao impacto da pandemia de COVID-19. A variação regional reflete diferenças na infraestrutura de saúde e acesso ao diagnóstico, sugerindo a necessidade de políticas públicas direcionadas para reduzir essas disparidades. CONCLUSÃO: Portanto, a análise das internações por TIC entre 2019 e 2023 mostra um aumento constante nas internações, com variações regionais influenciadas pela pandemia de COVID-19. A liderança da região Sudeste reflete sua infraestrutura avançada, enquanto o crescimento na região Norte sugere melhorias no atendimento. Esses dados ressaltam a necessidade de estratégias regionais adaptativas para aprimorar a prevenção e o manejo do TIC em todo o Brasil.
ASPECTOS RELACIONADOS À ENDOCARDITE FÚNGICA
Authors: Oliveira Verônica da Costa , Miranda Bezerra Lucas Frederico , De Almeida Soares Jonas Wagner , Dutra Mendonça Thiago , Mendes Guterres Maria Eduarda , Costa de Araújo Giovana Carolina , Sousa Mendonça de Medeiros Isaías , Queiroz Samineses João Gabriel , Silva Pinto Christian , Paiva Gomes Diogo Antonio , Possidônio de Souza Santos Inggryd Eduarda , Mendes Amaral Yan Caio
Published: September 2024

Introdução: A endocardite é uma infecção do endocárdio, a camada interna do coração que reveste as válvulas e as câmaras cardíacas. É uma doença de baixa frequência, considerada rara, e possui um diagnóstico desafiador. Metodologia: O objetivo deste estudo foi analisar as informações mais atuais e relevantes acerca da endocardite fúngica na literatura médica. Para isto, foi empregada uma abordagem metodológica e sistemática dos artigos encontrados em uma base de dados relevante e confiável, a Biblioteca Virtual em Saúde, conhecida como BVS. Resultados: Ao todo, 07 artigos foram selecionados para compor esta revisão. Conclusão: Pode-se observar com o presente estudo que a endocardite fúngica é uma doença rara, no entanto, com alta mortalidade. O diagnóstico é feito com base em exame de imagens e hemocultura, sendo a Candida sp. o agente causal mais isolado. Pacientes imunossuprimidos, bem como aqueles com algum tipo de comorbidade, infecção e história de cirurgia cardíaca são mais propícios a desenvolver a doença. O tratamento é feito à base de antifúngicos, no entanto, os medicamentos utilizados de forma isolada não são eficazes, sendo quase sempre necessária a abordagem cirúrgica de urgência. Ainda assim, mesmo que o tratamento clínico-cirúrgico seja instituído, a mortalidade chega a 80% dos casos nos estudos analisados, demonstrando a gravidade da condição.
APNEIA OBSTRUTIVA DO SONO COMO FATOR DE RISCO PARA HIPERTENSÃO ARTERIAL: UMA REVISÃO DA LITERATURA
Authors: Lima Pedro Paulo Gusmão de , Costa Fabiany Almada , Lima Gabriela Gusmão de , Junior Glauco Mol Santos , Neto Ivan Moreira , Mourão Matheus Marques , Silva Maria Clara Ataide Pereira , Guimarães Fernanda Alves , Lima Arthur Gabriel Martins e
Published: September 2024

A apneia obstrutiva do sono (AOS) é um distúrbio de elevada prevalência na população mundial, o qual se caracteriza por diversos intervalos de obstrução das vias aéreas superiores e interrupção do sono durante o repouso. Este distúrbio traz diversas consequências negativas, como o desenvolvimento de patologias cardiovasculares, elevação da pressão arterial, entre outras. Nesse contexto, estudos têm sido desenvolvidos com pacientes portadores da síndrome da apneia obstrutiva do sono, com o objetivo de investigar esta condição e, dentre os resultados, têm-se obtido que a AOS tem influência direta no desenvolvimento da hipertensão arterial e que o seu tratamento com diferentes dispositivos cursa com desfechos positivos na redução dos níveis pressóricos. Dessa maneira, tendo em vista as problemáticas diretamente desencadeadas pela hipertensão arterial, é notável a importância de conhecer esta correlação e abordá-la adequadamente para promover saúde, qualidade de vida e desfechos cardiovasculares favoráveis aos pacientes acometidos.
Using OOP Concepts for the Development of a Web-Based Online Bookstore System with a Real-Time Database
Authors: Harsh Vaidya  , Aravind Reddy Nayani  , Alok Gupta  , Prassanna Selvaraj  , Ravi Kumar Singh
Published: September 2024

This research paper explores the application of Object-Oriented Programming (OOP) concepts in developing a web-based online bookstore system integrated with a real-time database. The study investigates how OOP principles such as encapsulation, inheritance, and polymorphism can be leveraged to create a robust, scalable, and maintainable e-commerce platform for book sales. Additionally, it examines the implementation of real-time database technologies to enhance user experience and system performance. The research employs a comprehensive methodology, including system analysis, design, implementation, and testing phases. The findings demonstrate the effectiveness of OOP in structuring complex web applications and highlight the benefits of real-time databases in improving data synchronization and user interactivity. The study also provides insights into the challenges faced during implementation and offers solutions to overcome them, contributing valuable knowledge to the field of software engineering and e-commerce development.
EDUCAÇÃO INCLUSIVA PARA CRIANÇAS COM TRANSTORNO DO ESPECTRO AUTISTA: IMPACTO DE PRÁTICAS ADAPTADAS NO DESENVOLVIMENTO ESCOLAR
Authors: Eloan Alves da Silva
Published: September 2024

Introdução: Crianças com TEA apresentam dificuldades significativas em áreas como comunicação. Objetivo: Este trabalho tem o enfoque no impacto das práticas pedagógicas adaptadas no desenvolvimento escolar de crianças com Transtorno do Espectro Autista, com foco no uso de tecnologias assistivas, como a Comunicação Aumentativa e Alternativa, e metodologias personalizadas. Metodologia: A revisão abrange estudos e teóricos publicados entre 2018 e 2023, identificando as práticas mais eficazes na melhoria do desempenho acadêmico e socialização de crianças com TEA. A partir de uma triagem de 320 artigos, 8 estudos relevantes foram selecionados, revelando resultados promissores. Resultados: Os achados destacam que o uso de tecnologias assistivas e a personalização do ensino promovem avanços significativos no aprendizado e integração social dessas crianças, complementando os métodos tradicionais de ensino. Discussão: No entanto, barreiras como a falta de capacitação docente e de recursos nas escolas públicas foram identificadas, sugerindo a necessidade de mais pesquisas para confirmar a eficácia dessas intervenções e orientar a formulação de políticas educacionais mais inclusivas. Conclusão: Este estudo não apenas sintetiza as evidências sobre práticas pedagógicas inclusivas para crianças com TEA, mas também aponta direções para futuras investigações, ressaltando a importância de infraestrutura adequada e formação contínua de professores para garantir uma educação inclusiva de qualidade.
Formação de profissionais de enfermagem: uma reflexão sobre metodologias de ensino e aprendizagem
Authors: Cordeiro Soares Branco Juliana
Published: September 2024

Valendo-se de uma profunda revisão teórica e de entrevistas concedidas por discentes e docentes, a obra discute a formação de profissionais de enfermagem, evidenciando diferenças entre as metodologias de ensino-aprendizagem tradicionais e as Metodologias Ativas e o modo como elas interferem no processo de construção de conhecimento. A autora propõe uma importante reflexão sobre os avanços e percalços das instituições de ensino superior em ofertar cursos que integrem teoria e prática. Busca-se, dessa forma, promover o aprimoramento dos métodos pedagógicos, para que os profissionais formados estejam mais bem preparados para atender à população.
The effect of intestinal exotoxins sticks for hematology indicators and cytokine profile in the bloodstream of rats
Authors:   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Tishchenko Alexander S. , Koshchaev Andrey G. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Shantyz Azamat K. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Yakovenko Pavel P. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Sedashev Artem P. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Terekhov Vladimir I. ,   Pashkovsky Agricultural College, Krasnodar, Russia
Published: September 2024

Pathogenic escherichia, having a toxigenic potential, exhibit a cascade of pathological reactions in the body of animals. At the same time, the functional activity of the cells of the blood system will be a universal indicator for assessing the pathogenetic mechanisms in Escherichia toxicoinfection. The aim of the work was to study the effect of Escherichia exotoxins on hematological parameters and serum cytokine levels in rats during experimental infection. White Wistar rats were used as the object of the study. The infecting biomaterial was a microbial-free centrifuge of three clinical strains of Escherichia isolated from sick piglets and calves with genes of thermolabile, thermostable, pore-forming, shiga-like, subtilase exotoxins, colicins and hemolysins. The hematological parameters in animals were evaluated using an automatic analyzer, and the cytokine profile using commercial enzyme immunoassay systems. As a result, it was found that in the first hours after the administration of exotoxins, leukopenia and lymphocytopenia were recorded in the blood of animals. After 12 hours, neutrophilia progressed against the background of an increase in the proportion of lymphocytes in rats, while in animals injected with a cultural mixture of several exotoxins, the infectious process was accompanied by a toxic-allergic course, which was expressed by monocytosis and eosinophilia. From the side of red blood cell cells, erythropenia and thrombocytopenia were observed in rats 6 hours after infection, with developing signs of anemia by 24 hours of observation. It was found that the cytokine response during the first 6 hours was characterized by the production of pro–inflammatory mediators – IL-6 and TNF-α, after 12 hours – IL-2 and anti-inflammatory IL- 10. Understanding the role of cytokines and blood cells in the immune response to infection caused by Escherichia coli exotoxins is important for deciphering the mechanisms of disease development and developing effective strategies for the treatment and prevention of Escherichia coli.
Experimental study of endotracheal stents with biocompatible nanostructured coatings
Authors:   Russian Peoples’ Friendship University named after Patrice Lumumba, Moscow, Russia, Shchurov Alexey I. , Shchurov Igor V. ,   Russian Peoples’ Friendship University named after Patrice Lumumba, Moscow, Russia, Vatnikov Yuriy A. ,   Russian Peoples’ Friendship University named after Patrice Lumumba, Moscow, Russia, Zharikov Aleksey M. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: September 2024

To date, upper respiratory tract stenosis is a serious problem in pets, leading to increasing respiratory failure. This pathological condition can occur as an independent disease, such as various malformations against the background of destructive changes in the rings of the trachea, or as a result of oncological or other proliferative diseases. It can also occur as a result of iatrogenic effects, such as prolonged inhalation anesthesia or forced ventilation, in dogs. To date, the only therapeutic interventions that restore the patency of the trachea have been surgical interventions using endotracheal prostheses, or "stents". But the main problem with stenting is a local inflammatory reaction to the stent, which has to be dealt with by the use of systemic antibiotics and corticosteroids. Long-term systemic use of which leads to systemic disorders on the part of the body. Therefore, the search for local delivery methods is currently the most significant and relevant. The greatest interest in this regard is played by various biodegradable polymers based on polylactic acid with medicinal substances included in their structure.
ROLE OF CALCIUM, VITAMIN D AND VITAMIN D RECEPTORS IN PATHOGENESIS OF THEILERIOSIS IN CATTLE
Authors: Akhtar R , Khan K , Naseer M , Zahid B , Durrani U.F. , Jamil M.U.
Published: September 2024

The present study was conducted to examine the levels of calcium, vitamin D and Vitamin D receptor (VDR) in naturally-infected cattle with bovine theileriosis for understanding their role in the pathogenesis of the disease. A total of 100 cattle were selected, based on clinical signs in three districts of Punjab, Pakistan. Fifteen healthy animals were kept as negative controls. Blood samples were collected in EDTA containing vacutainer for Giemsa staining to examine the intra-erythrocytic forms of Theileria. Serum was collected in yellow top vacutainer for Vitamin D and calcium determination while plasma was also extracted for the determination of VDR levels from EDTA containing tubes. Giemsa staining showed 23% positive animals by microscopy while 32% of animals were positive by PCR. Levels of calcium, vitamin D, and VDR were very significantly (P<0.001) lower in Theileria affected animals in comparison to negative control. The results revealed that calcium, Vitamin D, and VDR might have a role in pathogensis of bovine theileriosis.
Keywords: Bovine Tropical Theileriosis; Calcium; Vitamin D; VDRs; T.annulata
Weak Contraction for Coupled Fixed Point using Q- Function
Authors: - Rajesh Shrivastava , - Sachin Mokhle
Published: September 2024

The purpose of this article is to prove coupled fixed point theorem for non linear contractive mappings in partially ordered complete quasi - metric spaces using the concept of monotone mapping with a Q- function q and (α - Ψ)- contractive condition. The presented theorems are generalization and extension of the recent coupled fixed point theorems due to Bhaskar and Lakshmikantham \cite(BL). We also give an example in support of our theorem.
Iran-Iraq Conflict: An Overview
Authors: - Dr. Aftabuddin Ahammad
Published: September 2024

Abstract: The Iran-Iraq Conflict, spanning from 1980 to 1988, was a prolonged and devastating war between Iran and Iraq. Initiated by Iraqi leader Saddam Hussein’s invasion of Iran, the conflict was driven by territorial disputes, particularly over the Shatt al-Arab waterway, as well as political and ideological differences. The war resulted in massive casualties and widespread destruction, with both sides suffering heavy losses. It involved trench warfare, chemical weapons, and significant economic strain. The conflict ended in a United Nations-brokered ceasefire, but no formal peace treaty was signed. The war had profound implications for both nations, shaping regional politics and military strategies in the years that followed.
A Review of Evaluating Deep Learning Techniques in Hepatic Cancer Imaging: Automated Segmentation and Tumor Quantification
Authors: - Yahya Abdul Rehman Shah , - Hamza Ahmed Qureshi , - Sara Muddassir Qureshi , - Saad Ur Rehman Shah , - Ashish Shiwlani , - Ahsan Ahmad
Published: September 2024

The classification and treatment of liver cancer, especially hepatocellular carcinoma (HCC), has been one of the significant problems in diagnosing and treating the disease. Previously, segmentation was done through manual processes, which were labour-intensive and highly variable. As a result, new methods for deep learning have been introduced. This article reviews the literature on using deep learning models for the automated segmentation of liver tumours using images focusing on their performance. The constraint for this review paper will be whether deep learning models improve diagnosis and treatment in people with hepatic cancer. In conformity with the PRISMA stipulations, 1295 distinct studies from 2014 to 2024 were examined, of which 100 were included in the final review. The investigation was conducted on various deep learning models’ performance measures to aid segmentation accuracy for U-Net and DeepLabv3+. Despite the difficulties, such as having diverse qualities of the data set, the generalizability of models themselves and the effects of observer variability on ground truth markings severely impact reported performance measures. Therefore, these two architectures are the most common among others and provide good accuracy, with the mean Dices index being 0.87 and 0.89, respectively. When it comes to the automatic segmentation of liver tumours, deep learning models, especially U-Net and DeepLabv3+, seem very promising due to their high precision in identifying target organs or structures within an image. Yet researchers still need to focus more on issues related to dataset variation, standardisation of evaluation metrics and their adoption in clinical settings. For instance, comprehensive validation should be conducted across different patient populations and imaging modalities to guarantee that it can be used in practice; otherwise, one may only have theory without application.
A Randomised Study to Evaluate and Compare the Safety of Intravenous vs Intramuscular Ketamine in Major Depressive Disorder with Suicidal Ideations
Authors: - Akanksha , - Ved Prakash Gupta , - Mohd. Asif Seraj , - Deoshree Akhouri
Published: September 2024

Background- Depression is a common psychiatric illness that can be very disabling. In severe instances, it can result in suicide. Being an emergency, ketamine has showed rapid response in terminating suicidality and reducing depressive symptoms.
Objectives- The aim of the study was to evaluate and compare the safety of intravenous and intramuscular ketamine in major depressive disorder.
Method- The present study was conducted in the MDD patients with suicidal ideations who were recruited from psychiatry OPD/IPD during the period November 2021 to October 2022. Ketamine was given at a dose of 0.5mg/kg as a single intravenous infusion in 100 ml NS for a period of 40 minutes or a single intramuscular injection on gluteal muscle and safety of ketamine was assessed on semi-structured proforma.
Results- In both groups, most common side effect was anxiety. Other side effects noted were nausea/vomiting, sedation/drowsiness, dizziness, heaviness of head, lightness of body, emotional abreaction, derealisation/depersonalisation, blurred vision, tachycardia, raised blood pressure and elevated mood. All side effects were transient and improved on its own within 24 hours. None of the participants withdrew because of the adverse effects of ketamine. So, ketamine can be a safer alternative when given by im route.
Plant Based Disease Detection Using CNN And SAM Model
Authors: - Mohit Solanki , - Dhairya Patel , - Kevin Mayani , - Rishab Kate , - Nalini Jagtap , - Shritika Wayker
Published: September 2024

Crop disease detection is pivotal for ensuring food security and sustainable agriculture. Traditional methods often struggle to accurately identify diseased plants, resulting in substantial yield losses. In agricultural contexts, detection of disease is very important so that we get maximum yield and ensures the crop quality or crop health. As we know that for any work related to images we often use CNN convolutional neural network as it work really great due to its architecture thus its use is often seen in leaf disease detection and mostly this traditional approaches use raw leaf image and feed it to CNN to train which may not work if the dataset is very low or we may not get satisfactory accuracy this is because it is not able to capture that pattern, and also in some scenarios diseases spots manifest as light or closely resemble the background coluor of the leaf thus it requires more data to discern such a subtle patterns.
Amnemonic Recall Based on 'Fast Movement' Categorisation Does Not Explain the Animacy Effect
Authors: - Ayushi Agarwal
Published: September 2024

Animate entities are better remembered than matched inanimate entities. The ultimate mechanism underlying the ‘animacy effect’ is evidently adaptative and foundational. However, the proximate explanation remains unclear. In this study we explored ‘fast-movement’ categorization as a potential proximate cause driving this effect. This study was largely based on the pioneering research by Nairne et al., (2013) and hence it adapted a similar paradigm of three trials involving presentation of words, followed by a distractor task and finally a recall task. The words were matched not only on the basis of linguistic features, but also on the basis of ‘fast-movement’ ratings. However, the results still showed a
robust animacy effect. Thus, we concluded that the memory advantage of animate items over inanimate items cannot be explained by differential motion categorisations.
Leveraging Artificial Intelligence Technology to Enhance Public Health and Promote a Steady Lifestyle
Authors: - Anand Babu
Published: September 2024

This paper investigates emerging global health concerns and the increasing prevalence of health issues among individuals. It explores the potential of artificial intelligence (AI) to positively impact personal lifestyles and promote healthier living. The study also delves into the integration of AI in healthcare, emphasizing its role in enhancing health outcomes while ensuring user privacy and data security. Through a comprehensive analysis, this paper highlights the transformative capabilities of AI in fostering a healthier society
India's National Rural Health Mission: A Critical Review of the Mission Implementation and Achievements
Authors: - Tharigopula Satheesh , - M.R. Gangadhar
Published: September 2024

People’s health is the State’s wealth. A majority of the population in India lives in the rural areas. Though there are many health policies in India, they could not reach the rural masses due to poor implementation. In the wake of this, the Government of India launched the National Rural Health Mission (NRHM) in April 2005 as a sub-mission of the National Health Mission.

The strategy in NRHM contains ‘Programme Implementation Plans’ for each state and it is more focused on special status states that are weak in public health indicators. The mission’s vision is to be more community-owned and decentralized in providing health care to the larger populations.

This paper attempts to review the mission’s objectives, implementation, and achievements. It also tries to examine the role of the new national health program of India ‘Ayushman Bharat’ through its objectives. In addition, the study evaluated the functioning of the mission in tribal areas of the country. It analyses the convergence and divergence of the new policy with the National Health Mission, but not merely a repetition of the same. Secondary analysis using the government reports, and published works on the mission was used in this study.
Prescription Pattern of Drugs used in Eczema Patients Visiting Dermatology Department
Authors: - SIJAMOL S , - VAISHNAVI PRASANNAN
Published: September 2024

Eczema is referred as the "itch that rashes" because of the dry skin that causes a rash when scratched or rubbed. It affects about 2-10% of adults and 15-30% of children during the course of their lifetimes. In India, prevalence of eczema ranges from 0.44 - 2.8%. 60% of instances start to manifest within the first year of life. The objective of the study was to assess the drug prescribing pattern in eczema and by identifying the prescription pattern helps the patients in lowering the burden of flares seen in eczema and also aid in the optimization of anti-eczema drugs with improved efficacy, minimal toxicity and to ensure the physical and psychological well-being of the patients. This was a Cross Sectional study, carried out in the Out-Patient Department of Dermatology, ESIC MC-PGIMSR and Model Hospital, Rajajinagar, Bengaluru. A total of 110 samples were collected, of which 10 were dropped out and 100 samples were selected for the study and statistically analyzed using Microsoft Excel. The study found that Corticosteroids, moisturizing agents, and antihistamines were mostly prescribed for the treatment of eczema. This will help to reduces symptoms, quicken healing of skin and prevent further skin damage.
Effective Use of Language for Teaching Children with Intellectual and Developmental Disability
Authors: - Ms. Jyoti Vaman Kharat , - Mr. Dnyaneshwar Lahanu Sawant
Published: September 2024

This research paper explores the effective use of language strategies tailored to the educational needs of children with intellectual and developmental disabilities (IDD). The study examines the role of language in facilitating cognitive development, social interaction, and academic achievement in children with IDD. Through a review of existing literature and case studies, the paper identifies key language interventions and instructional approaches that have been shown to improve learning outcomes for this population. The research highlights the importance of using clear, consistent, and multi-sensory communication methods to enhance comprehension and engagement. Additionally, the paper discusses the challenges teachers face in adapting language use to the varied needs of children with IDD and provides recommendations for professional development and inclusive education practices.
Assessing the Impact of Virtual Reality Integration in PET-CT Scans: A New Frontier in Radiology
Authors: - Madhur Nagrath
Published: September 2024

This study addresses the novel combination of virtual reality (VR) technology with positron tomography-like tomography (PET-CT) scanning and aims to revolutionize radiology as well as medical education and knowledge. In an age where complex medical concepts often hinder learning and understanding, VR has the opportunity to change the educational landscape by providing knowledge conversation to each other. To evaluate the effectiveness of VR- assisted PET-CT scans in providing easy-to-understand information to physicians and patients. This study aims to help patients receive treatment using VR technology. VR enhanced learning module. Through these experiments, the researchers attempted to measure the impact on the student's memory and the patient's mental state before and after learning the treatment process from the model. By analyzing qualitative data and user evaluations such as spatial perception and test accuracy, this research is designed to provide evidence to support the integration of VR into medical education and communication with patients. Attending medical education and patient counseling sessions. Additionally, VR- supported learning modules create a more inclusive and accessible learning experience as they have the ability to adapt to different learning styles and interests. This may change, specifically in radiology. By shedding the light on the impact of VR-enhanced learning experiences on both teachers and students, this study highlights the importance of using new technologies to meet the changing needs of patient interactions. Continue to highlight the potential and limitations of VR in improving medical education. By exploring new forms of VR technology, such as the integration of learning environments and self-directed learning experiences, researchers can continue to push the boundaries of medical education and pave the way for increased knowledge and support of medical staff. To conclude, integrating virtual reality into medical education promises free access to knowledge and fosters a culture of lifelong learning in the medical industry.
Analysis of the Current Marketing Strategies of Micro Small and Medium Enterprises (MSMEs) in Carcar City, Cebu, Philippines: Towards a Comprehensive Marketing Framework
Authors: - Jonreil S. Traya
Published: September 2024

This study examines the marketing strategies employed by Micro, Small, and Medium Enterprises (MSMEs) in Carcar City, Cebu, Philippines, with an emphasis on combining traditional and digital marketing strategies. The research involved surveys and interviews targeting MSMEs across diverse sectors including food, retail, manufacturing, and services. The analysis highlights the various challenges and opportunities faced by these enterprises in both traditional methods such as print advertising and outdoor advertising, alongside digital techniques like social media marketing and content marketing. Findings reveal that while traditional strategies maintain local trust and credibility, digital methods significantly expand market reach and engagement. The proposed comprehensive marketing framework synergizes these approaches, aiming to enhance the competitiveness and sustainability of MSMEs in Carcar City. This framework is designed to be adaptable, addressing the dynamic needs of businesses in the digital era while preserving the cultural and community-centric values integral to Carcar City’s commercial landscape. The study's insights are intended to guide MSMEs, policymakers, and stakeholders in fostering adaptable marketing practices that ensure long-term growth and resilience.
Evaluating the Protection of Traditional Music Under Uganda's Copyright Law: Challenges and Opportunities
Authors: - Niyokwizera Emmanuel
Published: September 2024

Uganda is largely a traditional society with many music works falling under the category of traditional music. The music industry is generally protected under the Copyright and Neighboring Rights Act 2006, and currently there are proposed amendments for the law. The research paper therefore seeks to highlight the state of protection for traditional music in Uganda and to explore if offering sound protection can create some opportunities for the creators, communities and the country
Gender in Chinese Language: A Study of Words containing Woman Radical in Chinese Characters
Authors: - Manju Rani Hara
Published: September 2024

It has been opined by many scholars of linguistics that Chinese language has a strong patriarchal bias. In the 20th century China, the linguistic and cultural bias in its language somehow remained intact despite the turbulent changes that China experienced thorough the processes of Socialist and modernist transformations. The paper, through the perspective of theory of Sociolinguistics and Markedness, will examine a selection of Chinese characters that contains women radical “女”, such as forms of address for women, certain nouns, verbs etc with women radical marking. The paper will also try to make a general attempt in understanding how certain words and terms in their deployment in communicative context are linked to influencing a person’s thought cognitively and socially.