bluuebunny/crossref_metadata_2025 huggingface dataset:
Conflictos en la Conciliación Trabajo y Maternidad en Contexto Rural
Authors: Mora-Guerrero Gloria , Seguel-Esparza Eduardo , Lagos-Marín Carolan , Díaz-Calderón Jassna
Published: October 2022

El trabajo de cuidados en el hogar se transforma en una barrera para la inserción de las mujeres en el mundo remunerado cuando tienen hijos/as menores de 6 años y se ven obligadas a compatibilizar la maternidad con sus trayectorias laborales. Esta problemática se agudiza en zonas rurales, donde las madres tienen acceso limitado a servicios formales de cuidado. En este contexto, se exploró la relación entre trabajo y familia a partir de la experiencia de mujeres que tenían al menos un hijo/a en edad infantil y eran residentes de sectores rurales del sur de Chile. Se trató de un estudio cualitativo, basado en 16 entrevistas a 12 participantes, que describió los conflictos de tiempo y tensiones, así como la postergación del ocio que experimentan las mujeres en el proceso de conciliación. Las conclusiones alientan a desnaturalizar la maternidad y promover el desarrollo rural a partir de la corresponsabilidad masculina en la crianza y el fortalecimiento de una agenda pública de equilibrio entre trabajos productivo y reproductivo.
Epilepsy and a woman – a woman has been found!
Authors: Karlov V. A.
Published: October 2022

Currently, the number of antiepileptic drugs (AEDs) has been growing. While choosing the most optimal AEDs by criteria of their efficacy, tolerability and retention time on therapy, many clinical factors, individual biological characteristics of any certain patient, as well as socio-economic aspects should be taken into account, including those associated with the burden on the health care system. In practice, a doctor is primarily focused on the best clinical result while health care is obliged to take costs into account. Calculating the ratio of benefits and costs associated with pharmacotherapy is not complete without comparing the cost of original and reproduced AEDs. For many, sometimes very weighty, reasons, an idea that the original AEDs are preferable in terms of clinical expectations from their use with a significant economic disadvantage (cost) has been established. In this paradigm, reproduced AEDs are always perceived as a compromise in which an acceptable result can be obtained at moderate cost, which is true for the generalized group of reproduced AEDs. However, there are many examples when AEDs do not differ from the reference agents. In particular, Seizar from the Alkaloid company (Republic of North Macedonia) has been recently in wide use in Russia as an alternative to the original lamotrigine. On October 5–6, 2021, the II International Conference “Epilepsy and Women” was held in Belgrade, wherein the leading experts from Serbia and Russia presented reports on the effectiveness and quality of care for epilepsy at the symposiums “Childhood with Seizar”, “Preparing for adulthood with Seizar”, “Assessment of the benefits and prospects of using Seizar at all stages of women’s life with epilepsy”, “Epilepsy and comorbidity – universal opportunities”. Here, we summarize selected messages presented during the conference.
Perspectiva histórica de la elasticidad del principio salva rerum substantia
Authors: Murillo Villar Henar
Published: October 2022

En este trabajo se analiza cómo la primitiva y originaria rigidez del principio salva rerum substantia fue atemperándose con el paso del tiempo. Ello se constata no solo en las propias fuentes jurídicas romanas, que ya manifestaban un desarrollo flexible del principio como consecuencia de la intervención jurisprudencial, sino también por la necesaria aceptación de la regulación del quasi ususfructus. Como resultado de la recepción del derecho justinianeo, en el derecho vigente se aprecian supuestos de usufructo que si bien no prescinden absolutamente del principio salva rerum substantia al menos ponen de manifiesto su absoluta elasticidad, es decir, su flexibilidad para adaptarse al régimen jurídico que se halla establecido. No obstante, lo fundamental en el derecho de usufructo son los derechos del usufructuario, uti et frui, siendo secundario, pero no por ello menos importante, pues es variable y modificable, el límite salva rerum substantia.
La representación procesal en Castilla: el personero y su relación con el vindex, el cognitor y el procurator
Authors: Valencia Virosta Alejandro
Published: October 2022

En la actualidad, la representación procesal es aquella función que desempeñan los procuradores de los tribunales al asumir la representación de las partes en todo tipo de procesos. No obstante, esta figura no es una creación reciente, sino que se remonta al Derecho Romano y, posteriormente, al derecho castellano. Para ello, en el presente estudio se analiza, por un lado, la figura del personero como representante procesal en el derecho castellano medieval, concretamente en el imponente texto de las Siete Partidas, y, por otro, en qué medida esta figura es originaria o derivada de sus predecesores romanos como, por ejemplo, del vindex (en el derecho arcaico) o del cognitor y procurator (en el derecho clásico).
Short-term results of two strategies in thoracoscopic ablation for lone atrial fibrillation
Authors: Zotov Aleksandr S. , Pidanov Oleg Yu. , Osmanov Ilkin S. , Troitskiy Aleksandr V. , Silayev Aleksandr A. , Sakharov Emil' R. , Sukhotin Vladimir N. , Shelest Oleg O. , Khabazov Robert I. , Timashkov Denis A.
Published: October 2022

Background: Thoracoscopic ablation is an effective treatment of patients with atrial fibrillation. Nowadays, 2 types of ablative devices are available in clinical practice allowing one to perform the thoracoscopic procedure Medtronic and AtriCure. However, the contemporary clinical literature does not have enough data that would compare these two approaches. Aims: to perform a comparative analysis of the short-term results of two minimally invasive strategies in thoracoscopic ablation for atrial fibrillation. Methods: 232 patients underwent thoracoscopic ablation for atrial fibrillation in two clinical centers for the period from 2016 to August 2021. The patients were divided into 2 groups. The first group was represented by those patients to whom a Medtronic device was applied (n=140), the second group was treated with an AtriCure device (n=92). The patients were comparable in their age, gender, initial severity of the condition. The follow-up consisted of laboratory tests, chest Х-ray, electrocardiography, 24-hour Holter monitor, echocardiography. The structure and prevalence of postoperative and intraoperative complications, specifics of the postoperative period were compared between the two groups. Results: According to the structure and prevalence of intraoperative complications the 2 groups are comparable to each other: 4.3% and 1.1% for the 1st group and 2nd group, respectively (p 0.05). The postoperative complications had developed in 6 (4.3%) and 5 (5.4%) patients in groups 1 and 2, respectively (p 0.05). At the time of discharge from hospital, a sinus rhythm was registered in 93.6% of patients (1st group), and 85.9% (2nd group) (p 0.05). Conclusions: Both strategies have demonstrated comparable short-term results in patients with lone atrial fibrillation. A further research is needed to evaluate the effectiveness of this strategy in a long-term period.
A rational strategy for the maintenance of antiviral immunity to new SARS-CoV-2 strains
Authors: Baklaushev Vladimir P. , Yusubalieva Gaukhar M. , Bychinin Mikhail V. , Yusubalieva Saule M. , Kalsin Vladimir A. , Troitskiy Aleksandr V.
Published: October 2022

New variants of SARS-CoV-2 such as Omicron BA.2, BA.4/5, BA.2.12.1 and BA 2.75 are characterized by higher infectivity and the ability to escape virus-neutralizing antibodies against previous coronavirus variants. The S-trimer of BA.2 and its phylogenetic derivatives are characterized by a predominant Up-conformation, which facilitates the interaction with ACE2 on target cells and promotes the resistance to neutralizing antibodies. The immunity acquired from the infection with earlier strains is non-sterile for both early and later strains; the booster systemic immunization does not significantly affect the effectiveness of antiviral immunity, and its feasibility is currently being questioned. Studies of the mucosal immune response have shown that intranasal immunization with adenovirus vaccines provides more pronounced protective immunity than systemic reimmunization does. A promising approach is the creation of multivalent inhaled next generation vaccines containing immunoadjuvants that activate B- and T-cell mucosal immunity. Currently, a large number of intranasal vaccines are undergoing phase I/II trials, while the preclinical and preliminary clinical results indicate that this method of vaccination provides a better mucosal immune response at the entry site of the virus than systemic immunization does. This strategy may provide a long-term immune protection against the currently existing and yet unknown new strains of SARS-CoV-2.
Why are Children Still Working?
Authors: Sandra Heri , Dawood Taufiq Carnegie , Abd. Majid M. Shabri
Published: October 2022

This study aims to determine the effect of household characteristics and children's living environment on child labor to reduce the likelihood of child labor occurrence. The data source of this research is Sakernas (Indonesian National Labor Force Survey) of August 2018, including school accreditation, household head gender, age, working sector, employment status, household size, dependency ratio, location, and school quality, towards the probability of child labor occurrence in Indonesia. Results suggest that the government must prioritize welfare programs for women household heads, asses the minimum age for marriage, improve education facilities, and increase parental awareness to eliminate child labor. The government needs to improve education infrastructure. This infrastructure improvement should be accompanied by the convenience of school access and its costs. The lack of education infrastructure, especialy in rural areas makes it difficult for children there to attend formal schooling.
Comparative Development of Indonesia and Nigeria in the First Two Decades of Democracy: Divergence or Convergence?
Authors: Babagana Adamu Waziri
Published: October 2022

Indonesia and Nigeria are considered suitable candidates for comparative analysis because of their similarities in natural endowments and geographical attributes, demography, economic structure, sociocultural diversity, and political history. Indonesia began to achieve rapid growth in the 1980s while Nigeria did not. During that period, economic policies in the two countries diverged, and this led to sustained economic growth in Indonesia and prolonged economic decline in Nigeria. However, as the countries transitioned to democratic rule in 1999 following the collapse of authoritarian regimes, some aspects of their political and economic trajectories revealed a trend towards convergence. Using the descriptive comparison of secondary data, the researcher analyzed those converging paths and the areas where the divergence continues. The study concludes that despite exhibiting more signs of convergence and dealing with similar challenges, the impact of initial conditions is likely to influence the developmental efforts in Indonesia and Nigeria.
The effect of hydrotherapy according to Halliwick concept on children with cerebral palsy and the evaluation of their balance: a randomised clinical trial
Authors: Chandolias Konstantinos , Zarra Evangelia , Chalkia Anna , Hristara Alexandra
Published: October 2022

Background: Hydrotherapy according to Halliwick concept is a physiotherapeutic intervention technique for disabled patients and for children with neurodevelopmental disorders. Assessing the balance in children with cerebral palsy (CP) is an extremely complex process and more difficult to evaluate the results of some therapeutic interventions in these patients. The purpose of this study is to investigate the effect of Halliwick based Hydrotherapy on the support base in children with CP. Several studies have proven the beneficial effects of hydrotherapy in the respiratory system of children, but few are studies that report the effect on the balance of children with CP.

Methods: The study involved 16 children diagnosed with CP. The 10 children were following a Halliwick Concept hydrotherapy program and the 6 children classical physiotherapy program for 3 months. Their balance was assessed with the Berg, GMFM, and footprint plate. The assessment was performed at the start of the program (pre-test) and after 3 months (post-test).

Results: Τhere is a statistically significant change between the 1st and 2nd measurement with the BERG and GMFM tools and better for the water intervention group. The change in the support base between the 1st and 2nd measurement was better in the water intervention group but not statistically significant.

Conclusions: The results of the study showed that hydrotherapy according to Halliwick has positive effects on gross mobility and the balance of children with CP. It also appears to have a positive effect on changing the support base compared to classical physiotherapy.
Strengthening the Security of Operational Technology: Understanding Contemporary Bill of Materials
Authors: Arora Arushi , Wright Virginia , Garman Christina
Published: October 2022

The evolution of cyber‐physical infrastructure has made its security more challenging. The last few years have witnessed a convergence of hardware and software segments in various domains, including operational technology (OT) which is responsible for carrying out critical tasks such as monitoring and controlling power grids, nuclear plants, transportation, and emergency services. Both hardware and software encapsulate numerous open source and proprietary subcomponents, making it crucial for end‐users to understand the composition of the products they are using. For example, wind turbines incorporate thousands of lines of code (software) used for the turbine's design, planning, operation, and analytics in addition to the numerous hardware subcomponents that construct it. Due to the highly complex nature of software and hardware, knowledge of the components and subcomponents is required to mitigate cyber vulnerabilities and to defend against cyberattacks.

There has also been a transformation from a traditional linear supply chain into a global, dynamic, diverse, and interconnected system. The digitization of the supply chain makes it easier to find and exploit vulnerabilities. Critical infrastructures (e.g., power grids, oil, natural gas, water, and wastewater) rely on OT to function, and if the OT is compromised, equipment damage and potential interruption of services could result. A significant security measure to protect OT systems from disruption is to develop a supply chain bill of materials (BoM) corresponding to the software and hardware used in OT, along with attestations amongst vendors and asset owners. A supply chain BoM is a proactive way to understand the inherent vulnerabilities in the system and mitigate them in advance of being exploited. BoMs bolster the trust placed in the digital infrastructure and enhance software supply chain security by sustaining the management of component obsolescence and compliance, along with the seclusion of unsafe segments of a specific product.

Adopting BoM tools is becoming increasingly important across various government sectors, as evidenced by the recent U.S. executive order on cybersecurity (NIST 2021). This paper aims to classify BoMs based on structure, functionality, component type, and architecture. The work also discusses case studies to further highlight the benefits of BoMs. In addition, it identifies missing pieces in existing BoM implementations so that future research may identify bounds on where it could expect to make improvements and directly enable researchers to identify promising areas for exploration. Further, the authors provide valuable recommendations to tool developers, researchers, and standardizing organizations (policymakers), additionally benefitting critical infrastructure owners and government executives. This aids in paving a path for future work, thereby, providing suggestions to determine a tool for consumers that best suit their needs.
The Artificial Intelligence Readiness for Pandemic Outbreak COVID-19: Case of Limitations and Challenges in Indonesia
Authors: Nurmaini Siti
Published: October 2022

Artificial intelligence (AI) technologies continue to play significant roles during the Coronavirus 2019 (COVID-19) pandemic in the world. However, health is an area where the rules are stringent and inflexible. This can be justified because it deals with human life. Nevertheless, at the same time, a large number of tests, certifications, and panels will lead to innovations in AI for healthcare that are longer, more complex, and difficult to incorporate into real-world applications. Indonesia has a lot of AI research, which is challenging to commercialize in medicine. These researches are not yet effective due to several limitations in terms of (i) the readiness of a skilled workforce to develop and use AI, (ii) the readiness of regulations that regulate the ethics of using and utilizing responsibly, (iii) the readiness of computational infrastructure and supporting data for AI modeling, and (iv) readiness industry and the public sector in adopting AI innovations. In pandemic outbreak COVID-19, AI technology should help the medical industry more significantly, caused by such limitations, and it has not yet been impactful against COVID-19 in Indonesia. In the future, AI technology exists as a complementary facility to increase the productivity of medical personnel and acts as a disease prevention facility.
Segmentation of the Lungs on X-Ray Thorax Images with the U-Net CNN Architecture
Authors: Pranata Teddi , Desiani Anita , Suprihatin Bambang , Hanum Herlina , Efriliyanti Filda
Published: October 2022

Lungs are one of the most important parts of the human body. They are very susceptible to various disorders and diseases. For this reason, it is necessary to detect or diagnose the lungs. In this study, we present a method for lung segmentation using the CNN method U-Net architecture. The initial stage was pre-processed did a 1-1 correspondence to equalize the amount of training data and testing data and resized the image so all images have the same size. The process continued with the CLAHE (Contrast Limited Adaptive Histogram Equalization), and after that, the segmentation process was carried out according to the method. This study used a dataset from the Kaggle website. The results used the CNN method of the U-Net architecture in data get an average accuracy of 91.68%, sensitivity 92.80%, and specificity 89.15%, precision 95.07, and F1-Score 93. 92%. Based on the performance evaluation results, it was concluded that the method proposed in the study is great and valid in the lungs segmentation on X-Ray Thorax images.
Measuring Inter-VM Performance Interference in IaaS Cloud
Authors: Derdus Kenga Mosoti , Oteke Vincent Omwenga , Ogao Patrick Job
Published: October 2022

Virtualization has enabled cloud computing to deliver computing capabilities using limited computer hardware. Server virtualization provides capabilities to run multiple virtual machines (VMs) independently in a shared host leading to efficient utilization of server resources. Unfortunately, VMs experience interference from each other as a result of sharing common hardware. The performance interference arises from VMs having to compete for the hypervisor capacity and as a result of resource contention, which happens when resource demands exceed the allocated resources. From this viewpoint, any VM allocation policy needs to take into account VM performance interference before VM placement. Therefore, understanding how to measure performance interference is crucial. In this paper, we propose a simple experimental approach that can be used to measure performance interference in Infrastructure as a Service (IaaS) cloud during VM consolidation.
Evaluating Naïve Bayes Automated Classification for GBAORD
Authors: Mustika Hani Febri , Syafiandini Arida Ferti , Manik Lindung Parningotan , Rianto Yan
Published: October 2022

The Indonesian Government Budget Appropriations or Outlays for Research and Government (GBAORD) has been analyzed manually every year to measure the government expenditures in research and development. The analysis process involved several experts in making the budget classification. This method, commonly known as manual classification, has its downsides, which are time consumption and inconsistent result. Therefore, a study about implementing the machine learning method in GBAORD budget classification to avoid inconsistency is proposed in the previous research. For further analysis, this paper evaluates the performance of the Naïve Bayes algorithm for the GBAORD budget classification. This paper aims to measure the robustness of the Naïve Bayes to classify GBAORD data taken from 2017 until 2019. This paper uses three models of Naive Bayes with different preprocessing methods and features. This paper concludes that using the Naïve Bayes algorithm in Indonesian GBAORD budget classification is suitable since the robustness of the algorithm is proved to be high with 96.788+-0.185% average accuracy.
Author Matching Classification with Anomaly Detection Approach for Bibliomethric Repository Data
Authors: Yamani Zaqqi , Nurmaini Siti , Rini Dian Palupi
Published: October 2022

Authors name disambiguation (AND) is a complex problem in the process of identifying an author in a digital library (DL). The AND data classification process is very much determined by the grouping process and data processing techniques before entering the classifier algorithm. In general, the data pre-processing technique used is pairwise and similarity to do author matching. In a large enough data set scale, the pairwise technique used in this study is to do a combination of each attribute in the AND dataset and by defining a binary class for each author matching combination, where the unequal author is given a value of 0 and the same author is given a value of 1. The technique produces very high imbalance data where class 0 becomes 98.9% of the amount of data compared to 1.1% of class 1. The results bring up an analysis in which class 1 can be considered and processed as data anomaly of the whole data. Therefore, anomaly detection is the method chosen in this study using the Isolation Forest algorithm as its classifier. The results obtained are very satisfying in terms of accuracy which can reach 99.5%.
Reviving the role of mecillinam against extended spectrum beta-lactamase producing enterobacterales
Authors: Kaleem Fatima , Aftab Irum , Farwa Umme , Saleem Hassan , Ishtiaq Saima , Abbasi Shahid Ahmad
Published: October 2022

Background and Objectives: This study was designed to determine the in vitro efficacy of mecillinam against extended spectrum beta lactamse producing Enterobacterales.
Materials and Methods: After proper permission from Ethical Review Committee of the Institute, all samples yielding growth of ESBL producingEnterobacterales were part of the study and were processed according to routine microbiological procedures. Routine antibiotic sensitivity testing was done onMuller Hinton Agar by Modified Kirby Bauer Method. All Gram negative isolates were subjected to concomitant detection of ESBL production by doubledisc synergy method. All ESBL producers were then subjected to the mecillinam Minimum Inhibitory Concentration (MIC) determination by E test. The results were interpreted as per CLSI Guidelines.
Results: A total of 120 ESBL producing Enterobacterales isolates were included in the study. The mean age of patients with ESBL infection was 45 ± 18.7years. There were 44% male and 55% female patients. Majority of the ESBL producing Enterobacterales were isolated from urine samples (56%), followed bypus. Among the isolated organisms, Escherichia coli (45%) was the most frequently isolated organism followed by Klebsiella spp. (22%). Overall 83% of theisolates turned out to be sensitive to mecillinam. MIC50 of mecillinam against ESBL producing Gram negative rods (GNR) turned out to be 1 ug/ml and MIC90 turned out to be 2 ug/ml.
Conclusion: Mecillinam shows good in vitro efficacy against ESBL producing Enterobacterales in our study. Further studies with more sample size and from diverse areas across the country should be done to evaluate its efficacy.
Lytic potential of a filamentous bacteriophage isolated from sewage water in Tehran on clinical carbapenem-resistant strains
Authors: Esmaeili-Fard-Barzegar Keyvan , Najar-Peerayeh Shahin , Mazaheri Nezhad Fard Ramin , Bakhshi Bita
Published: October 2022

Background and Objectives: Acinetobacter baumannii (A. baumannii), an opportunistic pathogen, has been isolated from sewage, soil, and hospital wards.The prevalence of multidrug-resistance A. baumannii has seriously caused a health crisis in hospital settings. Bacteriophages have been used as an alternativetherapy for control carbapenem-resistant bacteria-caused infections. We aimed to assay lytic effect of a filamentous phage on clinical bacterial strains.
Materials and Methods: 500-ml water samples was collected from sewage in Tehran. Sewage samples were precipitated at 6000 rpm for 10 minutes andfiltered using 0.45-µm syringe filters. Bacteriophage was isolated using double-layer agar assay and evaluated its stability at various pH and temperatureranges. In addition, the stability of the phage was assayed at chloroform 0.1%.
Results: Transmission electron microscopy imagine showed phage is filamentous called vB-AbaI-TMU2. The phage affect- ed on its own host so that couldnot effect on any Pseudomonas aeruginosa and Klebsiella pneumoniae strains. vB-AbaI- TMU2 phage was stable at pH 5 and 7 and also temperatures 25 and37°C. vB-AbaI-TMU2 was stable at chloroform 0.1%. vB-AbaI-TMU2 phage infected carbapenem-resistant A. baumannii strains while other bacterial strainswere resistant to.
Conclusion: The present study indicated the isolated phage had a narrow host range and is susceptible to various pH values and temperatures.
Isolation, characterization, and antibacterial activity of lytic bacteriophage against methicillin-resistant Staphylococcus aureus causing bedsore and diabetic wounds
Authors: Rezaei Zeinab , Elikaei Ameneh , Shafiei Morvarid
Published: October 2022

Background and Objectives: Phage therapy has gained interest as an alternative treatment for methicillin-resistant Staph- ylococcus aureus (MRSA)infections. The purpose of this study was to isolate and characterize an effective bacteriophage against isolates of MRSA.
Materials and Methods: Bacteriophage was isolated from hospital sewage. Lytic activity and the titers of phage lysates were measured using spot test anddouble-layer plaque assay. The phage characterization was determined through trans- mission electron microscopy. Adsorption rate, host range and stabilitytests were investigated. The latent period and burst size were estimated from a one-step growth curve. The effect of bacteriophage against MRSA biofilms wasdetermined and Real-time PCR was used to assess the effects of the bacteriophage on the expression of the biofilm-associated genes.
Results: TEM resultsshowed that the phage resembled the Cystoviridae family. Its latent period was 30 min, corresponding to about 71/43 phage particles per infected cell. Thephage had a broad host range and it was most stable at 37°C and pH 7. It was sensitive to NaCl concentrations. The expressions of the biofilm-associated genes were significantly reduced in the presence of the phage.
Conclusion: The isolated phage was effective against MRSA strains and it can be an optional strategy of controlling biofilm development.
Characterization of the conserved regions of E1A protein from human adenovirus for reinforcement of cytotoxic T lymphocytes responses to the all genogroups causes ocular manifestation through an in silico approach
Authors: Omidi Nahid , Azaran Azarakhsh , Makvandi Manoochehr , Khataminia Gholamreza , Ahmadi  Angali Kambiz , Jalilian Shahram
Published: October 2022

Background and Objectives: Adenovirus species B, C, D, and E are the most common causes of ocular manifestations caused by adenoviruses. FDA-approved treatment agents for adenovirus infections are not available. Cell-mediated im- munity is the major protective mechanism versus humanadenoviruses (HAdVs) infection and T cells specific for peptide epitopes from nonstructural proteins can prevent adenoviral dissemination. E1A CR2 regionof HAdVs Epitopes predicted for reinforcing cytotoxic T lymphocytes (CTLs) in the EKC patients. Among human adenoviruses E1 protein, four distinct E1Aregions had a significantly higher level of homology than the rest of E1A protein. E1A protein inhibits IFN signal trans- duction. Epitope-based vaccines aredesigned to have flexible and simple methods to synthesize a vaccine, using an adjuvant to trigger fast immune responses. CTL epitopes were applied to create amultiepitope vaccine. Conserve region1 (CR1) and CR3 have less antigenicity compared to CR2. Additionally, CR3 in HAdV-D8 contains three toxic areas. CR4 similar to the two regions CR1 and CR3 do not show acceptable antigenic properties.
Materials and Methods: Bioinformatics’ tools were used to predict, refine and validate the 3D structure of the construct. Effective binding was predicted byprotein-protein docking of the epitope vaccine with MHC-I molecules and revealed the safety and efficacy of the predicted vaccine construct.
Results: In silico analysis show that rising levels of cytotoxic CD8 + T cells, TH1 cells, macrophages, and neutrophils are linked to IFN-dominant TH1-type responses, which are detected in putative immune individuals.
Conclusion: Combined with 3D protein modeling, this study predicted the epitopes of E1A CR2 protein in HAdVs.
The Relation between Worker Protection System in the Interpersonal Service and Workplace Violence as Well as Workers’ Depression
Authors: Choi Eun-Hi , Jung Myung-Hee , Beak Eun-Mi , Jung Hye-Sun , Lee Bokim
Published: October 2022

Background: We aimed to confirm the effect of interpersonal service worker protection system on workplace violence and depression and to determine the relationship among the protection system, workplace violence, and depression.
Methods: Self-reporting survey was conducted for approximately a month beginning on 2 March 2020, among members selected using the convenience sampling method from seven labor unions in South Korea to which interpersonal service workers belonged. The questionnaire consisted of questions regarding the subjects’ general characteristics, worker protection system, workplace violence, and depression. Overall, 1,541 workers participated in this study.
Results: The basic model was used to test the relationship between the protection system and depression, with a mediating effect of workplace violence. Three of the hypothesized paths were significant (P<.001), but the basic model did not fit the data. In the revised model, the direct path from the protection system to depression was deleted. Path coefficient of the direct effect of the protection system on violence was -0.05, the direct effect of the violence on depression was 0.77, and the indirect effect of the protection system on depression was -0.04. The fit of this model was acceptable.
Conclusion: Organizational interventions have an indirect effect on reducing depression by preventing workplace violence; however, there was no direct effect on reducing the depression of the workers. These results justify the need to invest in strengthening workplace protection systems for the interpersonal service workers.
Relationship between Participation in Physical Activity and Subjective Well-Being: Evidence from Korea during the Pandemic
Authors: Bae Myeong-Hun
Published: October 2022

Background: The lack of physical activity because of restrictions from the pandemic has increased interest in the deterioration of mental and physical health. This is the first study in Korea to investigate how participation in physical activity is correlated with subjective well-being among Koreans in the early stages of the COVID-19 pandemic.
Methods: The survey was conducted among those aged >13 years, from August 24 to September 7, 2020. The process included self-reported surveys, telephone surveys, and face-to-face household interviews; 11,604 people (men=7,758 and women=3,846) participated. Frequency, correlation, and one-way analysis of variance were performed to identify differences between age and sex groups according to the physical activity level, while post-hoc Scheffe tests to examine between-group differences when significant results were observed.
Results: Statistically significant correlations were observed between life satisfaction, living environment satisfaction, and levels of happiness and anxiety based on sex and age (P<0.05). There were significant differences between frequency and time spent on physical activity and subjective well-being according to sex and age (P<0.05).
Conclusion: The study results are highly generalizable considering the analysis of a large-scale sample within a big area in Korea. The findings emphasize that subjective well-being is influenced by sex, age, frequency, and time spent engaged in physical activity. Such basic data can be helpful for establishing policies related to physical activity.
Application of Different Continuous Renal Replacement Therapy Hemofilter in Patients with Septic Shock Complicated with Acute Renal Injury
Authors: Liu Shanqing , Cao Quanxia , Sun Rui , Wang Nan
Published: October 2022

Background: We aimed to compare the clinical effects of continuous renal replacement therapy (CRRT) with different hemofilters in patients with septic shock and acute kidney injury (AKI).
Methods: Thirty patients with septic shock complicated with AKI admitted to The Fourth Affiliated Hospital of Anhui Medical Universityfrom 2018-2020 were selected and divided into the control and observation groups. The control group was treated with CRRT using theconventional ST-100 hemofilter. The observation group was treated with CRRT using the oXiris hemofilter for 48 hours, followed by CRRT with the conventional ST-100 hemofilter. Infection indexes, sepsis-related organ failure assessment (SOFA), changes in corresponding organ function indexes, duration of each treatment, and death were compared between the two groups during CRRT.
Results: The white blood cells (WBC) count, high-sensitivity C-reactive protein (hs-CRP), and procalcitonin (PCT) levels were significantly decreased in the oXiris group 48 hours after CRRT (P= 0.048, 0.036, 0.031, respectively). After 48 hours of CRRT, SOFA score, serum lactic acid, and norepinephrine dose in the oXiris group were significantly lower than those in the control group (P= 0.039, 0.002, 0.021, respectively). The use time of vasoactive drugs and the treatment time of CRRT in the oXiris group was significantly shortened (P= 0.031 and 0.029, respectively). However, there were no significant differences in mechanical ventilation duration, intensive care unit (ICU) hospitalization time, total hospitalization time, ICU mortality, and in-hospital mortality.
Conclusion: For patients with septic shock complicated by AKI, CRRT treatment with the oXiris hemofilter could effectively clear inflammatory cytokine levels and quickly correct hemodynamic disorders, thus accelerating the recovery of organ function.
Assessing the Relationship between Economic Development and Mental Wellbeing in South Korea
Authors: Thompson Ephraim Kwashie , Kim So-Yeun
Published: October 2022

The Article’s Abstract is not available.
Uncommon Daily Life/Daily Uncommonness. Everyday Life under Conditions of Risk and Uncertainty
Authors: Taranowicz Iwona
Published: October 2022

According to the proponents of the sociology of everyday life, the practices of everyday life maintain the order of social life. Berger and Luckmann argue that such practices are characterised by habitualness and unreflectiveness; they seem natural and self-evident, not requiring justification. However, their statement is no longer valid. It was not only the COVID-19 pandemic that violently disrupted the established order of everyday life. Even before the pandemic, processes of social change had occurred, and these processes shattered the unified vision of the world, the nomos in which all social practices found their justification. The sheer multiplicity of knowledge and belief systems that now exist, as legitimate as they are, forces individuals to be reflexive and to make choices from among different patterns of action. At the same time, new processes of change are constantly taking place that challenge the validity of previous choices. The COVID-19 pandemic did not start these processes, but it did exacerbate these processes. The question for researchers is how do individuals construct the order of their everyday life in these uncertain and risky conditions, an order whose constancy and predictability, as Giddens states, has always been a bulwark against fear and insecurity.
Risk in the Biographies of Independent Care Leavers
Authors: Wiktorowicz-Sosnowska Monika
Published: October 2022

The article presents selected results of qualitative research indicating an attempt of self-construction by alumni of creating institutional and family forms of care in relation to experiences, autonomy and risk (including the risk associated with the COVID-19 pandemic). It appears that not the pandemic but adaptation to life outside institution affects the vulnerable life balance which, in light of lack of possibilities and resources necessary to overcome difficulties, sets the direction life course of the research participants. These difficulties lead to the implementation of certain functioning strategies which translate into life choices. The empirical data comes from quality in-depth interviews which make it possible to examine the world experienced and perceived by individuals.
Embodied cognition: looking inward
Authors: Nowakowski Przemysław R.
Published: October 2022

The body is a highly complex, coordinated system engaged in coping with many environmental problems. It can be considered as some sort of opportunity or obstacle, with which internal processing must deal. Internal processing must take into account the possibilities and limitations of the particular body. In other words, even if the body is not involved in the realization of some cognitive explicit task, it is not a neutral factor of our understanding of why a system solves a task in one way or another. Therefore, when conducting research on embodiment and the body’s cognitive system we should not neglect internal, cognitive processing.

            I appeal to Goldman’s research on embodied cognition to sketch the broader framework for internal processing in embodied cognition. I believe that even if we don’t accept Goldman’s approach as the viable proposal for embodied cognition in general, it’s a quite natural starting point for our analysis. Goldman (2012; 2014, and with de Vignemont 2009) argue for the essential role of the bodily formats or bodily codes (respectively: B-formats and B-codes) in embodied cognition. B-codes are here described as the processing of regions or sub-regions of the central nervous system. They are primarily employed for body control or monitoring, and reused for cognitive tasks.  Beyond doubt, this conception provides an excellent starting point for analyzing the internal (mostly neural) processing in cases of embodied cognition.

            At the end of this paper, I will argue that the embodiment of cognition needs a conceptual twist. Following Keijzer’s (2015) interest in the evolution of the nervous system, and the minimal forms of cognition, I argue that in investigating embodied cognition, we should investigate the role played by cognitive processing for specific kinds of organisms, meaning organisms with a body of a particular morphology (size, shape, kinds, and distribution of sensors and effectors). Doing that, I refer to some conceptual and empirical considerations. I will also try to show that research on embodied cognition is still not sufficiently anchored in evolutionary and comparative studies on cognition, nor on the nervous system and body morphology. Bigger reliance on these kinds of studies, will make it make possible to gain a deeper understanding of internal processing in embodied cognition.
Cultured sand sea cucumber growth with different water exchange systems
Authors: Liubana Debora , Joi Alfreddi Surbakt  , Claudya Zyta Tobu
Published: October 2022

ABSTRACT
Sand sea cucumber (Holothuria scabra) is a high economic value as a food source. Sea cucumbers contain beneficial bioactive compounds for health. This study determined the sea cucumber growth cultured in an integrated multi-trophic aquaculture (IMTA) with different water exchange systems in Lifuleo waters from October to December, 2020. This study was performed in an experimental method with three different exchange system treatments and three replications, namely once every 2 days (tank A), every day (tank B), and water circulation every day (tank C). Briefly, sand sea cucumbers with 116.72 ± 117.91 g body weight and 11.06 ± 11.83 cm length were maintained for 45 days with different water exchange systems and fed with Eucheuma cottonii. The results showed that the best water exchange systems to increase sand sea cucumber production was tank A with 100% survival rate, 1.84 ± 0.06%/day specific growth rate, and 1714.96 ± 34.13 μm length growth rate. The water quality parameters were also optimal during the sand sea cucumber with the integrated system.
Keywords: Multi-trophic, growth, circulation, integrated system, sand sea cucumber
 
ABSTRAK
Teripang pasir (Holothuria scabra) mempunyai nilai ekonomis tinggi dan diperdagangkan sebagai bahan pangan. Selain itu teripang juga mengandung senyawa bioaktif yang bermanfaat untuk kesehatan. Penelitian ini mengkaji tentang pertumbuhan teripang yang dibudidayakan secara integrated multi-trophic aquaculture (IMTA) dengan sistem pergantian air yang berbeda di perairan Lifuleo pada bulan Oktober sampai Desember 2020. Penelitian ini dilakukan dengan metode eksperimental dengan tiga perlakuan 3 ulangan dengan sistem pergantian air 2 hari sekali (bak A), pergantian air setiap hari (bak B) dan sirkulasi air dilakukan setiap hari (bak C). Secara singkat, teripang dengan bobot badan 116.72 ± 117.91 gr dan panjang 11.06 ± 11.83 cm dipelihara selama 45 hari dengan sistem pergantian air dan diberi makan dengan Eucheuma cottonii. Hasil penelitian menunjukkan bahwa media perlakuan teripang dengan sistem pergantian air yang berbeda terbaik untuk meningkatkan produksi teripang adalah bak A dengan tingkat kelangsungan hidup 100, laju pertumbuhan spesifik harian 1.84 ± 0.06%/hari dan laju pertumbuhan panjang 1714.96 ± 34.13 µm. Parameter kualitas air juga menunjukkan kualitas yang optimal pada budidaya teripang secara terintegrasi.
Kata kunci: Multitropic, pertumbuhan, sirkulasi, terintegrasi, teripang pasir
Dioramas e fotogramas em conflito
Authors: Andrade Márcio Henrique Melo de
Published: October 2022

No documentário autobiográfico A Imagem que Falta, o cineasta cambojano Rithy Panh relata suas memórias sobre a instauração da ditadura comunista perpetrada pelo Khmer Vermelho no Camboja entre 1975 e 1979. Um dos atos para implementação desse regime consistiu no apagamento dos arquivos pessoais dos habitantes da cidade de Phnom Penh – álbuns de família, roupas, objetos. Ao mesmo tempo, o regime também produziu filmes de propaganda para representar a ditadura como lugar de harmonia, ordem e progresso, assim como imagens dos prisioneiros nos campos de trabalho. No filme de Rithy Pahn, o diretor retoma esses arquivos e os tensiona com a ausência de imagens que descrevam sua experiência pessoal. Nessa escrita de si alinhavada à elaboração de uma narrativa histórica, Pahn cria pequenos dioramas e bonecos de argila que funcionam como palcos e cenários de suas memórias. Nessa montagem entre fotogramas e dioramas, o diretor toma como forma o ensaio fílmico e seus recursos, como os usos poéticos dos materiais de arquivo, a dialética entre imagens de origens e estéticas distintas e a relação entre imagens factuais e discursos subjetivos. Neste artigo, analisa-se como a forma do ensaio no filme amplia os modos de interpretação da imagem documental e renegocia as formas de escrita da narrativa histórica, compreendendo como ambos se atravessam a partir da montagem.
Livro e emoção
Authors: Pochmann Pâmela da Silva , Freitas Ernani Cesar de , Simões Antunes Junior Fernando , Portella Montardo Sandra
Published: October 2022

Este artigo tem como objetivo refletir sobre a influência dos booktubers na assimilação dos livros que comentam por meio de resenhas literárias e, para tal, se propõe a jogar luz sobre o processo de patemização dos discursos que constituem estes vídeos. Para isto, utilizam-se os conceitos de patemização e de contrato comunicativo, de Charaudeau, tendo como objetivo descrever como as visadas patêmicas utilizadas nos vídeos podem influenciar o mercado editorial e, consequentemente, o livro que está sendo analisado pela booktuber. O corpus de análise é composto por um vídeo de resenha com spoilers do livro “O morro dos ventos uivantes”, da autora Emily Brontë, publicado pela booktuber Ju Cirqueira no dia 10 de outubro de 2021, em seu canal do YouTube. A pesquisa é descritiva, bibliográfica, e com abordagem qualitativa por meio da Análise do Discurso. Como resultado, identificou-se que há diversos momentos em que são empregadas visadas patêmicas na vídeo-resenha e que essas emoções contribuem para a visibilidade, credibilidade e notoriedade da booktuber na sua comunidade e no mercado editorial.
Determination of Exercise Attitudes of Pregnant Women
Authors: Acari Sevgi , Sivrikaya Omer
Published: October 2022

It is known that pregnancy is essential in the contribution of exercise to human health and the formation of healthy societies. Phenomenology design, one of the qualitative research techniques, was used in the research. The attitudes of pregnant women towards exercise before and during pregnancy and the factors affecting these attitudes were examined. The research group comprises 10 pregnant women, who are university graduates and work as professionals, who voluntarily participated in the research while living in Düzce. It is assumed that university graduates and professional pregnant women are the most qualified part of society in terms of health awareness and sports habits. A semi-structured interview form was used to collect data. Face-to-face interviews were conducted with pregnant women from different professions and at different stages of their pregnancy. NVIVO 11 statistical program was used in the analysis of the data. Although the participants thought that it was beneficial for their health, it was determined that they had various fears. Due to these fears and the fact that specialist doctors do not recommend exercise, even pregnant women who did not have any problems during their pregnancy avoided exercising. It was observed that the exercise attitudes of the participants before and during pregnancy differed.