bluuebunny/crossref_metadata_2025 huggingface dataset:
La presencia del objeto en la emancipación de las relaciones escénicas
Authors: Jijón Pamela
Published: December 2019

A partir del estudio de caso de la obra Esas putas asesinas, adaptación libre del cuento de Roberto Bolaño, creada por el Colectivo Mitómana Artes Escénicas en Quito en 2014, nos preguntamos cómo las presencias objetuales pueden constituirse en un eje del desplazamiento en las relaciones jerárquicas al interior de la escena y con el público.

Analizaremos la importancia del lugar como condición de la aparición objetual, insistiremos en la necesidad de establecer un trato creativo marcado por la delicadeza y el reconocimiento de la afectación mutua entre el sujeto-actor y el objeto; y terminaremos mostrando que, en el desplazamiento de lo cotidiano a lo siniestro, podemos abrir el mundo material hacia múltiples posibilidades de existencia e interpretación.
Terapia systemowa jako forma pomocy rodzinie
Authors: Rojewska Ewa
Published: December 2019

Artykuł przedstawia terapię systemową jako możliwą i skuteczną formę pomocy rodzinie. Przedstawione są w nim treści dotyczące systemowego rozumienia rodziny oraz znaczenia rodziny dla jakości życia jej członków. Główną część tekstu stanowią refleksje na temat istoty systemowej terapii rodzin oraz jej użyteczności.
Improvement in Mathematics Learning Outcomes in ‎Fraction Operation Material with Grid Square Unit Media
Authors: Rohmah Asha Septianti Nur
Published: December 2019

This research was motivated by MI Ma'arif Kutowinangun fifth grade students who have difficulty in receiving the lessons with materials related to addition and subtraction of various fractions. Especially, when dealing with addition and subtraction of fractions operations with different denominators. This was showed by the results of interviews and observations made by the author. With minimum completeness criteria of 60, from 14 students of V class, only nine of them reached the minimum completeness criteria, and the rest have not been able to achieve the minimum completeness criteria.Based on the above problems, then the author conducted Classroom Action Research (CAR) to determine the improvement of mathematics learning outcomes in fraction operation material with grid square unit media. The research subject was fifth grade students of MI Ma’arif Kutowinangun consisting of 20 students, 11 of them were female and nine of them were male. While, the data collection was obtained through interviews, observation, and evaluation results through written tests which then were analyzed by percentage.Based on this research, there was improvement of student mathematics learning outcomes in fraction operation with grid square unit media. From 20 students who reached the minimum completeness criteria 60 in the first cycle was 16 students or 80%. Then it increased in the second cycle that all fifth grade students of MI Ma'arif Kutowinangun reached the minimum completeness criteria or 100%.
Plastoquinone: possible involvement in plant disease resistance.
Authors: Maciejewska Urszula , Polkowska-Kowalczyk Lidia , Swiezewska Ewa , Szkopinska Anna
Published: December 2019

The plant Solanum nigrum treated with the pathogen Phytophthora infestans-derived elicitor responded by elevated reactive oxygen species (ROS) production, lipid peroxidation and lipoxygenase (EC 1.13.11.12) activity in comparison with control plants indicating that oxidative stress took place. We demonstrate that these events are accompanied by a significant increase in plastoquinone (PQ) level. It is postulated that PQ may be associated with mechanisms maintaining a tightly controlled balance between the accumulation of ROS and antioxidant activity that determines the full expression of effective defence.
Kış Turizmi Potansiyeli Açısından Muş İlinin SWOT Analizi İle Değerlendirilmesi
Authors: ARSLAN Emin , KENDİR Hakan
Published: December 2019

Türkiye’nin
Doğu Anadolu Bölgesi’nde yer alan illerde, kış turizmine yönelik önemli bir
potansiyelin bulunduğu ancak belli merkezlerde yatırımların yoğunlaştığı
görülmektedir. Geçmişte var olan terör olaylarının son yıllarda bitirilmesiyle
birlikte Doğu Anadolu Bölgesi’nin kış turizmine yönelik daha fazla yatırım
çekmesi olasıdır. Ancak Muş ili kış turizmi yatırımı anlamında henüz istenilen
noktada bulunmamaktadır. Bu çalışma kapsamında, kış mevsiminin oldukça sert
geçtiği ve kış turizmine yönelik (Güzeltepe Kayak Merkezi gibi) imkânların
bulunduğu Muş ilinde, kış turizmi potansiyelinin değerlendirilmesi ve kış
turizmi olanaklarının ortaya konması amaçlanmaktadır. Çalışma kapsamında GZTF
analizi yöntemi kullanılmıştır. Yapılan bu araştırma ile Muş ilinin bir kış
turizmi destinasyonu olarak hak ettiği konuma ulaştırılabileceğinin karar
vericiler tarafından fark edilmesi hedeflenmektedir.
Engelli Bakım Merkezi Yöneticileri ve Tükenmişlik
Authors: IŞIKHAN Vedat , AYALP Mustafa Çağrı , AYGÜLER Edip
Published: December 2019

Bu
araştırmanın amacı, Aile, Çalışma ve Sosyal Hizmetler Bakanlığına bağlı engelli
bakım merkezlerinin yöneticilerinin tükenmişlik düzeylerine etkide bulunan
faktörleri, yöneticileri strese bağlı olarak etkileyen önemli sağlık
sorunlarını ve yöneticilerin sunulan hizmetin kalitesinin artırılmasına yönelik
düşüncelerini saptamaktır. Hazırlanan görüşme formu ve Maslach Tükenmişlik
Ölçeği (MTÖ) Türkiye’de Engelli Bakım ve Rehabilitasyon Merkezinde görev yapan
104 yöneticiye uygulanmıştır. Yöneticilerin, MTÖ’nün üç alt boyutu olan
duygusal tükenmeden: 1,47; duyarsızlaşmadan: ,956 ve kişisel başarı noksanlığından:
2.94 puan aldıkları ve “düşük tükenmişlik” düzeyine sahip oldukları
saptanmıştır. Yaş, eğitim durumu, iş doyumu, tükenmişlik yaşama ve aileye
yeterince zaman ayırma durumlarının duygusal tükenme boyutunda; aileye
yeterince zaman ayırma durumunun duyarsızlaşma boyutunda; eğitim ve aileye
yeterince zaman ayırma durumunun kişisel başarı noksanlığı boyutunda
istatistiki anlamda farklılık yarattığı görülmüştür (p<0,05).
The Effect of Polymer Capping Group to the Electrocatalytic Water Oxidation Activities of Prussian Blue Analogues
Authors: ÜLKER Emine
Published: December 2019

The Prussian Blue (PB) nanoparticles can be
obtained by reacting the hexacyanometal center with metal ions in the existence
of polymers such as polyethyleneglycol (PEG). In this study, a pentacyanometal
complex, [Fe(CN)5NO]2-, was used in addition to hexacyanometal
ion, [Fe(CN)6]3-, to obtain nanoparticles coated with
PEG. PB nanoparticles have been prepared, characterized, and comprehensive
electrochemical studies were performed to investigate their performance for
water oxidation electrocatalysis. The effect the ratio of PEG to the morphology
and the water oxidation electrocatalytic performance have also been
interrogated. Overall, the study clearly indicates that Co-FeNO@PEG with 1:10
and 1:25 Co:PEG rate show the best electrocatalytic activity with an overpotential
of 472 and 489 mV for current density of 1 mA cm-1, respectively.
Critical Data Studies, Abstraction & Learning Analytics
Authors: Buckingham Shum Simon
Published: December 2019

This editorial introduces a special section of the Journal of Learning Analytics, for which Neil Selwyn’s keynote address to LAK ’18 has been written up as an article, “What’s the problem with learning analytics?” His claims and arguments are engaged in commentaries from Alfred Essa, Rebecca Ferguson, Paul Prinsloo, and Carolyn Rosé, who provide diverse perspectives on Selwyn’s proposals and arguments, from applause to refutation. Reflecting on the debate, I note some of the tensions to be resolved for learning analytics and social science critiques to engage productively, observing that central to the debate is how we understand the role of abstraction in the analysis of data about teaching and learning, and hence the opportunities and risks this entails.
Moving Forward with Learning Analytics: Expert Views
Authors: Ferguson Rebecca , Clow Doug , Griffiths Dai , Brasher Andrew
Published: December 2019

Learning analytics involve the measurement, collection, analysis, and reporting of data about learners and their contexts, in order to understand and optimise learning and the environments in which it occurs. Since emerging as a distinct field in 2011, learning analytics has grown rapidly, and early adopters around the world are already developing and deploying these new tools. This paper reports on a study that investigated how the field is likely to develop by 2025, in order to make recommendations for action to those concerned with the implementation of learning analytics. The study used a Policy Delphi approach, presenting a range of future scenarios to international experts in the field and asking for responses related to the desirability and feasibility of these scenarios, as well as actions that would be required. Responses were received from 103 people from 21 countries. Responses were coded thematically, inter-rater reliability was checked using Cohen’s kappa coefficient, and data were recoded if kappa was below 0.6. The seven major themes that were identified within the data were power, pedagogy, validity, regulation, complexity, ethics, and affect. The paper considers in detail each of these themes and its implications for the implementation of learning analytics.
Arterial hypertension in older adults: who needs geriatric approach?
Authors: Kotovskaya Y. V. , Tkacheva O. N.
Published: December 2019

Elevated blood pressure (BP) is an important risk factor not only for cardiovascular morbidity and mortality, but also for cognitive decline and loss of autonomy in later life. Randomized clinical trials (RCTs) in populations of older patients living at home with low comorbidity and preserved autonomy showed benefits of decreasing the elevated BP in patients older than 80 years. Older patients with frailty, loss of autonomy and other geriatric problems were systematically excluded from the RCTs. Observational studies in these groups of patients showed an increase in morbidity and mortality at a lower level of BP during antihypertensive therapy. Obviously, in very elderly patients a universal strategy for the BP lowering cannot be applied due to the significant heterogeneity of their functional status. In this review geriatric approach based on assessment of the functional status of the elderly patient, the presence of frailty and degree of loss of autonomy as a basis for decision-making process regarding the antihypertensive therapy is discussed.
Possible mechanisms of renal denervation long-term cardiac effects
Authors: Zyubanova I. V. , Mordovin V. F. , Pekarskiy S. E. , Ripp T. M. , Falkovskaya A. Yu. , Lichikaki V. A. , Sitkova E. S. , Baev A. E. , Gusakova A. M. , Ryabova T. R.
Published: December 2019

Background.The renin-angiotensin-aldosterone system (RAAS) plays a key role in target organ damage in arterial hypertension (HTN), initiating the development of left ventricular hypertrophy (LVH), as well as the heart and vascular wall fibrosis and remodeling. In addition, one of the mechanisms of the cardiovascular disease progression is the angiotensin II-induced inflammation.

Objective.To study the changes in renin, aldosterone and high-sensitive C‑reactive protein (CRP) levels two years after sympathetic renal denervation (RDN), to compare these changes with antihypertensive efficacy of the intervention and LVH regression.

Design and methods.We included 77 patients with drug-resistant hypertension in the absence of contraindications to renal denervation. All patients underwent renal radiofrequency ablation. The active renin, aldosterone and a high-sensitive CRP concentrations assessment, 24‑hour blood pressure (BP) measurement and echocardiography were performed before, at 6 months, one and two years after the intervention.

Results.There was a gradual decrease in CRP levels (the difference was significant after 6 months), aldosterone (significant two years after surgical treatment), and active renin (the difference was the most pronounced after one year). At all follow-up assessments, plasma renin activity correlated with left ventricular mass. At the same time, there were no significant differences between responders and non-responders.

Conclusions.RDN leads to a RAAS activity attenuation, manifested by the decrease in both renin and aldosterone and CRP, probably due to angiotensin II proinflammatory effects reduction. Given these effects are long-term, correlate with LVH degree and unrelated to the BP lowering, a direct cardioprotective effect of renal denervation should be considered.
Karta Praw Podatnika w polskim systemie podatkowym w świetle doświadczeń zagranicznych
Authors: Sęk Małgorzata
Published: December 2019

Celem artykułu nie jest omówienie formy i treści Karty Praw Podatnika w poszczególnych państwach, lecz dokonanie pewnych uogólnień na podstawie analizy rozwiązań funkcjonujących w różnych systemach prawnych oraz proponowanych w ramach międzynarodowych inicjatyw mających na celu upowszechnienie i ujednolicenie koncepcji Karty. Uogólnienia te będą podstawą do sformułowania w zakończeniu artykułu wstępnych wniosków dotyczących roli, formy i treści, jaką mogłaby przybrać Karta w warunkach polskiego systemu podatkowego.
An Experimental Investigation of the Perceived Credibility of Complainants of Sexual Revictimization: Disbelief and Victim-Blame
Authors: Wager Nadia M.
Published: December 2019

This study investigated whether attitudes toward a complainant of sexual assault are affected by the knowledge that the complainant had previously made a similar allegation. This was a 3 (previous allegation; none, child sexual assault or adult sexual assault) × 2 (whether the previous allegation was substantiated) × 2 (the implied mental health status of the complainant; mental health issue vs. none) multifactorial, experimental study, employing independent-measures and hypothetical vignettes depicting stranger rape scenarios. The dependent variables were victim-blame and believability. The participants were 243 female undergraduate students. A multivariate analyses of variance (MANOVA) revealed several main and interactive effects. Allegations of sexual revictimization were associated with different levels of victim-blame and believability depending on when the previous assault occurred. A history of childhood sexual assault reduced the believability of the complainant and when combined with other factors increased the tendency to attribute victim-blame.
Factors Associated With Types of Sexual Assault Victimization and Bystander Behavior Among South Korean University Students
Authors: Kim Dong Ha , Um Myung-Yong , Cho Hyunkag , Lee Eui Bhin , Chun Jong Serl , Chang Heesuk
Published: December 2019

The aim of the current study was to gain understanding about incidences of sexual misconduct and bystander behaviors in South Korean universities. Specifically, risk factors were examined associated with three different types of sexual assault victimization (verbal or visual sexual harassment, physically forced sexual assault, and incapacitated sexual assault) and investigated the factors related to bystander behaviors. Data were collected via an online survey tool called SurveyMonkey in 2016. The total sample of participants comprised 1,944 enrolled undergraduate and graduate students from six universities in Seoul, South Korea. One logistic regression was conducted with a sample who reported sexual assault victimization (n= 1,079) to examine the risk factors associated with the three types of sexual misconduct. The other logistic regression was conducted with the subsample of bystanders (n= 540) to examine the relationships between bystander behavior and risk factors. In the main results, each type of sexual misconduct was associated differentially with age, alcohol blackouts, depression, child abuse and neglect, being an international student, and childhood sexual victimization. Also, persons who were older, self-identified LGBT, and victimized by verbal or visual sexual harassment at university were more likely to intervene when sexual misconduct occurred. These findings have implications for policies and interventions to reduce and prevent sexual misconduct in Korean universities.
International Student Perceptions of American Gun Culture and School Shootings: A Public Health Examination
Authors: Gelzhiser Justin Adam
Published: December 2019

A shooting in an American education institution quickly creates a global ripple effect, due to the large number of international students enrolled in American secondary schools and higher education institutions. International students studying in the United States may offer unique insight into local and global perceptions of American gun culture, highlight the transnational physical, emotional, and psychological impact of gun violence, and offer fresh understandings about the American gun violence public health problem. A qualitative research study was conducted at The University of California, Los Angeles (UCLA) that included focus groups and in-depth interviews of students from China and India. These nations represent the largest American international student populations. The study included a random sampling methodology. Findings show that gun violence in American schools is a major concern for prospective international students and their families. While concerns about targeted-shootings diminish, students develop behaviors that indicate a pervasive fear of indiscriminate attacks (e.g., mass shootings and petty crime), such as avoidance of large public gatherings and traveling in groups for safety. They also question university campuses' unfettered visitor access and remain perplexed by the ease of gun access in America, which they directly attribute to causing America's gun violence problem. Social and mass media play large roles in perception-building processes by supplying accurate and real-time as well as fake or misleading information. However, divergent viewpoints emerge among family members concerned for their overseas relatives' safety while international students develop more refined perspectives.
Acompañamiento técnico como herramienta de formación en los proyectos productivos de los estudiantes de ingeniería agronómica de la Universidad de La Salle
Authors: Cárdenas Pardo Nestor Julián , Flechas Hernandez David Leonardo , García Sterling Maria Alejandra
Published: December 2019

La Universidad de La Salle contribuye a la educación rural nacional a través del proyecto Utopía, el cual forma a jóvenes provenientes de zonas rurales en condiciones de vulnerabilidad como ingenieros agrónomos.
Dentro del programa académico, los estudiantes realizan un proyecto productivo agrícola en sus zonas de origen al finalizar su ciclo de estudios en el campus de la universidad. Los diferentes proyectos son acompañados técnicamente por la Coordinación de Proyectos Productivos –adscrita a la Rectoría–, mediante un equipo de profesionales que realizan una labor pedagógica a través de la visita técnica de campo. Esta se constituye en una valiosa herramienta de apoyo técnico para el buen desempeño de los proyectos productivos y fortalece los conocimientos técnicos previamente adquiridos por los estudiantes. A diciembre de 2018, se habían realizado 400 visitas técnicas, aproximadamente, en gran parte del territorio nacional. Estas visitas técnicas han fortalecido el desempeño de los proyectos productivos que, a su vez, han impactado técnicamente las diferentes zonas rurales donde son ejecutados
Saberes tradiciones sobre manejo de mulares en el área central-andina de Colombia
Authors: Velásquez Mosquera Juan Carlos , Correa Rojas Indira , Corrales Álvarez Juan David
Published: December 2019

Los mulares en Colombia son usados para diferentes actividades agrícolas relacionadas con transporte y carga de insumos y cosechas. En el occidente de Cundinamarca se desarrolla actividad agrícola de caña panelera donde se usan mulares como animales de carga. Se adelantó un estudio exploratorio usando encuestas para conocer algunos saberes sobre manejo de mulares por parte de productores paneleros de cinco municipios de esta región, con quienes se indagó sobre criterios de escogencia animal, rutina de trabajo, sanidad y alimentación. La mayoría de los productores (93 %) preferían animales de tamaño medio, con rango de edad de 6 a 14 años. El promedio de carga por animal fue de 158 kg en jornadas de 9 horas. Muy pocos propietarios conocían el peso de sus animales y las prácticas sanitarias en esta especie fueron escasas. La mayoría de los propietarios alimentaban a sus animales con pasto y todos los suplementaban con melote, un subproducto de la actividad panelera. Estos hallazgos permitieron conocer algunos saberes tradicionales, pero, en general, fue notorio un escaso conocimiento de manejo zootécnico de la especie en la zona de estudio
Lectura crítica para tiempos de espectáculo
Authors: Elizalde Prada Óscar A.
Published: December 2019

A la luz de la teoría crítica de la sociedad del espectáculo (Debord, 1967) y sus posteriores desarrollos de cara a lo híper-espectacular (Silva, 2012), este texto aborda la perspectiva de una lectura crítica –afín a los sistemas educativos universitarios– favorable a la construcción de sujetos que sean, al mismo tiempo, críticos y autocríticos.
Propuestas didácticas en educación superior rural. Caso Utopía
Authors: Sánchez-Cañón Elkin , Rios Moyano Diana Katerinne , Sosa Rico Miguel Dario
Published: December 2019

El presente artículo tiene como propósito sistematizar las propuestas didácticas en un contexto de educación superior rural, específicamente en el caso Utopía. Para tal fin se expone el principio pedagógico ‘aprender haciendo y enseñar demostrando’ que da origen a la práctica en las líneas productivas. En seguida se exponen las estrategias didácticas que han venido enriqueciendo la práctica productiva, como los seminarios de investigación, la bancarización de las líneas productivas, y la práctica productiva articulada. Cada una de ellas permiten concluir que una de las características principales de la didáctica pasa por la praxis de los conocimientos como herramienta fundamental para el aprendizaje y el desarrollo de capacidades
Ressignificação da memória da cidade do Recife nas letras de frevo do maestro Nelson Ferreira
Authors: Santana Renata Jeane de , Pinho Fabio Assis
Published: December 2019

O tema deste artigo aborda as letras de frevo como documento e sua relação com a memória social e afetiva; por isso, trata-se de uma pesquisa de caráter exploratório e documental cujo objetivo principal foi considerar, a partir das letras de frevo do maestro pernambucano Nelson Ferreira, a relevância da informação musical para a reconstituição da memória da cidade do Recife. Para tanto, estabeleceu-se como corpus as letras de frevo-canção e frevo de bloco do músico, gravadas nas duas coletâneas da extinta fábrica de discos Rozenblit: O que eu fiz e você gostou... de 1959 e O que faltou e você pediu... de 1968, adotando como método a avaliação qualitativa da Análise de Conteúdo. Assim, os 39 frevos demonstraram, por meio de quatro categorias temáticas, que as letras são um produto de seu tempo, mas que também são um produto do olhar e da experiência de um homem em sua época, a qual, a partir do fenômeno da reprodutibilidade da informação, foi então massificada e perpetuada por quase 100 anos, repetindo-se por meio das narrativas das canções que, ao serem tocadas, ativam essa memória, trazendo-a para o presente e diluindo a memória individual de cada um, criando vínculos sonoros.
A elaboração de resumos documentários como atividade do tratamento temático da informação na prática profissional bibliotecária
Authors: Oliveira Lais Pereira de , Martínez-Ávila Daniel , Guimarães José Augusto Chaves
Published: December 2019

Considerando o resumo documentário enquanto elemento inerente ao tratamento temático da informação, analisa-se em que medida é elaborado durante o processamento técnico nas bibliotecas, como forma de apoiar a indexação para garantir uma representação temática completa dos materiais. Valendo-se de coleta dos dados mediante questionário com perguntas fechadas, aplicado via Google Formulários a 30 bibliotecários goianos em atuação em diferentes tipos de unidades de informação, procede-se a uma sistematização estatística. Os resultados indicam que a elaboração de resumos documentários não é uma prática comumente conduzida pelos bibliotecários, em detrimento da classificação e da indexação. O resumo está presente em apenas 16,7% das unidades de informação, apesar de enxergado em sua relevância por 96,7% dos respondentes. Evidenciam-se, ainda, dificuldades de diversas ordens para sua elaboração. Conclui-se que o resumo, apesar de reconhecido pelos profissionais investigados em sua importância, não está sendo aproveitado nas unidades de informação como parte do tratamento temático da informação como, de fato, deveria acontecer.
ANALISIS JENIS USAHA DAN LABA ATAS BIAYA PADA PEDAGANG DI KABUPATEN MANOKWARI
Authors: Usman Sarah
Published: December 2019

The objective of this research is to analyze the potential of local traders' economic growth in Manokwari Regency, West Papua based on the type of product sold and the profit to cost ratio. This research uses a quantitative descriptive approach. The research sample consisted of 74 respondents taken randomly using a simple random sampling method at the traditional markets of Sanggeng Market and West Market. Data were processed using SPSS with descriptive statistical methods-frequency. Results showed that the most products sold in traditional markets in Manokwari Regency were tubers and fruits by 28.4%, followed by sea/livestock products and mixed products by 24.3%, and vegetables by 23%. The lowest profit to cost ratio was 0.9 and the highest was 60. The average profit to cost ratio was 7.52 which means that traders in Papua should have been at a better welfare level. Likewise, local businesses should have been grown better. Increasing local trader welfare is also increasing the level of local economic growth. However, many traders can only earn income to fulfill their daily needs. Therefore, they should improve their business skills and knowledge by following some business training and assistance programs.
The ranks of service class population in the cities and counties of the southern frontier of Russia in the year 7185
Authors: Skobelkin Oleg
Published: December 2019

We analyze data on the ranks of service class people in the cities and counties of the southern frontier of Russia in 1676/77. We identify 39 cities with and without counties, which can undoubtedly be attributed to the southern frontier. We raise the problem of determining the north-ern border of the southern Russian frontier in the 2nd half of the 17th century. We identify thirteen ranks of service class people of the urban service. We considered the distribution of thirteen ranks in 39 cities. Based on the obtained data, we calculate the number of ranks in each city/county. In addition, we reveal the prevalence of each rank in the cities and counties of the southern Russian frontier.
Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B
Authors: Joyce M. Gordon , Bao Amy , Chen Man , Georgiev Ivelin S. , Ou Li , Bylund Tatsiana , Druz Aliaksandr , Kong Wing-Pui , Peng Dongjun , Rundlet Emily J. , Van Galen Joseph G. , Wang Shuishu , Yang Yongping , Zhang Baoshan , Chuang Gwo-Yu , McLellan Jason S. , Graham Barney S. , Mascola John R. , Kwong Peter D.
Published: December 2019

Background: Respiratory syncytial virus (RSV) subtypes, A and B, co-circulate in annual epidemics and alternate in dominance. We have shown that a subtype A RSV fusion (F) glycoprotein, stabilized in its prefusion conformation by DS-Cav1 mutations, is a promising RSV-vaccine immunogen, capable of boosting RSV-neutralizing titers in healthy adults. In both humans and vaccine-tested animals, neutralizing titers elicited by this subtype A DS-Cav1 immunogen were ~ 2- to 3-fold higher against the homologous subtype A virus than against the heterologous subtype B virus.Methods: To understand the molecular basis for this subtype difference, we introduced DS-Cav1 mutations into RSV strain B18537 F, determined the trimeric crystal structure, and carried out immunogenicity studies.Results: The B18537 DS-Cav1 F structure at 2-Å resolution afforded a precise delineation of prefusion F characteristics, including those of antigenic site Ø, a key trimer-apex site. Structural comparison with the subtype A prefusion F indicated 11% of surface residues to be different, with an alpha-carbon root-mean-square deviation (RMSD) of 1.2 Å; antigenic site Ø, however, resulted in 23% of its surface residues and had an alpha-carbon RMSD of 2.2 Å. Immunization of vaccine-tested animals with DS-Cav1-stabilized B18537 F induced neutralizing responses ~100-fold higher than with postfusion B18537 F. Notably, elicited responses neutralized RSV subtypes A and B at similar levels and were directed towards both conserved equatorial and diverse apical regions.Conclusion: We propose that structural differences in apical and equatorial sites–coupled to differently focused immune responses–provide a molecular explanation for observed differences in elicited subtype A and B neutralizing responses.Keywords: antigenic site; crystal structure; epitope; fusion glycoprotein; immunogenicity; neutralization; RSV subtype; vaccine
Cicatrizadores personalizados: relato de caso
Authors: Assada Fábio , Dos Santos Silva Rafael , Lorenzi Poluha Rodrigo
Published: December 2019

Quando feita a instalação de um implante imediato pode se optar entre a instalação de uma coroa provisória clínica, um cicatrizador ou pode se optar pelo fechamento do implante para um tratamento em duas etapas cirúrgicas. O uso de cicatrizadores personalizados sela os implantes e leva a uma cicatrização individualizada, que favorece a confecção das coroas subsequentes. O presente trabalho objetiva relatar um caso clínico envolvendo um implante imediato e a instalação de um cicatrizador personalizado, demonstrando os resultados e a importância de conhecimento dessa técnica pelo cirurgião-dentista.
Terapias para disminuir la sensibilidad por blanqueamiento dental
Authors: Achachao Almerco Kelly , Tay Chu Jon Lidia Yileng
Published: December 2019

El blanqueamiento dental tiene como principal efecto adverso la sensibilidad que se da como una respuesta pulpar a los radicales libres del peróxido de hidrógeno. Existen diferentes terapias utilizadas antes, durante y después para disminuir la sensibilidad dental, como el uso de agentes que actúan inhibiendo la re polarización del nervio como el nitrato de potasio en sus distintas presentaciones de gel, dentífricos o asociado al agente blan- queador y los que obliteran los túbulos entre ellos el fofato de calcio amorfo, silicato de calcio y sodio, gluconato de calcio, hidroxiapatita, GLUMA y ﬂúor; existen otras terapias alternativas como el uso de antiinﬂamatorios, vitaminas y aplicación de láser las cuales también han sido mencionadas en la literatura. La siguiente revisión tiene como objetivo analizar la evidencia cientíﬁca sobre los diferentes métodos para disminuir la sensibilidad por blanqueamiento dental.
KINETIKA PENJERAPAN SIMULTAN KROMIUM(III) DAN NATRIUM MENGGUNAKAN AMBERLITE IR-120 H (TINJAUAN PENGARUH SUHU)
Authors: Haitami Iqbal , Mulyono Panut , Hidayat Muslikhin
Published: December 2019

Abstrak - Limbah cair yang mengandung Cr(III) dan Na secara bersamaan sering dijumpai pada hasil kegiatan industri, terutama industri penyamakan kulit. Cr(III) yang merupakan logam berbahaya harus dapat dihilangkan dari limbah cair tersebut. Salah satu metode yang efektif digunakan untuk menangani pencemaran Cr(III) dalam limbah cair adalah pertukaran ion menggunakan resin penukar ion. Prinsip metode ini, yaitu menukarkan ion yang tersedia pada resin penukar ion dengan ion-ion yang berada di sekitarnya. Kehadiran Na dalam larutan tempat dijerapnya Cr(III) dengan menggunakan Amberlite IR-120 H, membuat fenomena ini tergolong sebagai penjerapan multikomponen. Dalam hal ini, penjerapan Cr(III) dan Na oleh Amberlite IR-120 H terjadi secara bersama-sama (simultan). Penelitian ini bertujuan untuk mempelajari laju penjerapan simultan yang terjadi pada berbagai suhu. Di samping itu, ingin dikembangkan model matematis untuk mendekati kinetika penjerapan simultan yang ada. Hasil penelitian menunjukkan bahwa semakin tinggi suhu, maka akan semakin besar laju penjerapan simultan Cr(III) dan Na. Kecenderungan yang sama ditunjukkan oleh nilai konstanta kinetika yang semakin besar seiring meningkatnya suhu. Model matematis yang disusun berdasarkan persamaan laju reaksi cukup sesuai untuk mendekati kinetika penjerapan simultan ini. Berdasarkan nilai energi aktivasi sebesar 56,735 kJ/mol untuk penjerapan Cr(III) yang terjadi, maka dapat dikatakan bahwa laju reaksi adalah laju yang mengontrol proses.Kata kunci: Kromium(III), penjerapan, kinetika, Amberlite IR-120 H, simultan
ANALISIS SPEKTROSKOPI INFRAMERAH TRANSFORMASI FOURIER (FTIR) DAN PERUBAHAN WARNA LIGNOSELULOSA ALANG-ALANG (Imperata cylindrica) SETELAH PRETREATMENT MENGGUNAKAN ASAM ENCER
Authors: Fauziah Asma , Rodiansono Rodiansono , Sunardi Sunardi
Published: December 2019

Abstrak. Alang-alang (Imperata cylindrica) mengandung sekitar 59% holoselulosa dan dapat digunakan sebagai bahan baku bioetanol. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pretreatment menggunakan asam encer terhadap karakteristik struktur kimia pada lignoselulosa alang-alang. Pretreatment dilakukan menggunakan asam encer dengan konsentrasi H2SO4 1%, 2%, 3% dan 4% pada suhu 210°C dalam autoclave selama 45 menit. Analisis perubahan struktur secara kimia setelah pretreatment dengan asam encer dilakukan menggunakan Spektroskopi Inframerah Transformasi Fourier (FTIR). Analisis perubahan warna dilakukan dengan metode CIELAB. Hasil yang diperoleh dari spektra FTIR mengindikasikan bahwa asam encer mendekontruksi strukur kimia dari alang-alang dengan melarutkan hemiselulosa selama proses pretreatment. Perubahan warna (ΔE) berkolerasi dengan modifikasi struktur kimia pada lignoselulosa alang-alang. Kata Abstrak. Alang-alang (Imperata cylindrica) mengandung sekitar 59% holoselulosa dan dapat digunakan sebagai bahan baku bioetanol. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pretreatment menggunakan asam encer terhadap karakteristik struktur kimia pada lignoselulosa alang-alang. Pretreatment dilakukan menggunakan asam encer dengan konsentrasi H2SO4 1%, 2%, 3% dan 4% pada suhu 210°C dalam autoclave selama 45 menit. Analisis perubahan struktur secara kimia setelah pretreatment dengan asam encer dilakukan menggunakan Spektroskopi Inframerah Transformasi Fourier (FTIR). Analisis perubahan warna dilakukan dengan metode CIELAB. Hasil yang diperoleh dari spektra FTIR mengindikasikan bahwa asam encer mendekontruksi strukur kimia dari alang-alang dengan melarutkan hemiselulosa selama proses pretreatment. Perubahan warna (ΔE) berkolerasi dengan modifikasi struktur kimia pada lignoselulosa alang-alang. Kata kunci: Imperata cylindrica, hidrotermal, asam encer, FTIR
PIROLISIS MINYAK GORENG BEKAS DENGAN KATALIS ZEOLIT TERAKTIVASI NaOH
Authors: Abdullah Abdullah , Putra Yudha Adi Pratama , Irwan Azidi
Published: December 2019

Abstrak-Minyak goreng bekas dapat digunakan sebagai bahan baku sumber energi alternatif. Minyak goreng bekas mempunyai rantai hidrokarbon panjang yang dapat dipecah untuk menghasilkan senyawa alkana dan alkena melalui proses pirolisis. Penelitian ini bertujuan untuk menghasilkan pirolisat sebagai bahan bakar alternatif berupa bio-oil dengan katalis yang telah teraktivasi larutan NaOH. Selain itu penelitian ini bertujuan untuk mengetahui kemampuan bio-oil yang dihasilkan dan dibandingkan dengan minyak tanah sebagai bahan bakar kompor. Pirolisis minyak goreng bekas telah dilakukan dengan zeolit yang diaktivasi menggunakan larutan NaOH (1, 2, 3, 4, dan 5M). Konsentrasi optimum aktivasi terjadi pada proses karakterisasi zeolit dengan uji daya serap terhadap larutan methylene blue dan uji keasaman dengan metode adsorpsi desorpsi amonia yang menghasilkan larutan NaOH 4M sebagai konsentrasi optimum. Pirolisis dilakukan dengan variasi jumlah zeolit (0, 5, 10, 15, dan 20%) terhadap minyak goreng bekas dengan parameter pengamatan pada proses pirolisis berupa data mengenai yield, lama pirolisis, dan perubahan massa katalis pergram. Hasil optimum pirolisat diperoleh pada proses pirolisis menggunakan katalis sebanyak 20%. Analisis komponen kimia penyusun pirolisat dengan GC-MS menunjukkan kandungan hidrokarbon sebesar 81,93%. Pirolisat hasil pirolisis minyak goreng bekas berpotensi sebagai bahan bakar alternatif pengganti minyak bahan bakar kompor. Kata kunci: Pirolisis, minyak goreng bekas, zeolit, aktivasi katalis, GC-MS
OPTIMASI PROSES KOAGULASI MENGGUNAKAN CAMPURAN KOAGULAN ALUMINIUM SULFAT DAN POLY ALUMINIUM CHLORIDE (1:1) PADA PENGOLAHAN AIR SUNGAI TELLO
Authors: Widiyanti Setyo Erna , Pabbenteng Pabbenteng , Saputra Eko Wardana , Islamiati Andi Nurul
Published: December 2019

Abstrak- Koloid dan padatan total tersuspensi (TSS) dalam air dapat dihilangkan dengan proses koagulasi dan flokulasi. Konsentrasi koagulan dan pH merupakan dua parameter terpenting dalam keberhasilan proses koagulasi dan flokulasi. Tujuan dari penelitian ini adalah optimasi pH proses koagulasi dan flokulasi menggunakan campuran koagulan Alum dan PAC (1:1) untuk menghilangkan TSS air sungai Tello. Sampel yang digunakan dari penelitian ini adalah Air Sungai Tello yang memiliki konsentrasi TSS awal 195 mg/L. Konsentrasi campuran koagulan Alum dan PAC (1:1) yang digunakan sebesar 25% dari konsentrasi TSS awal sampel. Kondisi proses koagulasi dan flokulasi yang digunakan adalah pengadukan cepat (koagulasi) dengan kecepatan pengadukan 350 rpm selama 1 menit, pengadukan lambat (flokulasi) dengan kecepatan pengadukan 50 rpm selama 20 menit, dan pengendapan selama 30 menit. Proses koagulasi dan flokulasi dilakukan pada kisaran pH 4-10 dan konsentrasi TSS dianalisa menggunakan metode Gravimetri. pH proses koagulasi dan flokulasi dan persen (%) removal TSS optimal pada pH 6 dengan persen (%) removal TSS sebesar 98,20%. Kata kunci: Alum, Koagulasi, PAC, pH, TSS
FİRMA DEĞERLEME YAKLAŞIMLARI VE TÜRK HAVA YOLLARI (THY) ÜZERİNE BİR UYGULAMA
Authors: ÜNVAN Yüksel Akay
Published: December 2019

Bu çalışma kapsamında, rekabet koşullarının her geçen gün
zorlaştığı küresel finans pazarında önemini giderek daha da arttıran firma
değerleme kavramı ele alınarak, öncelikle konuyu işleyen çeşitli çalışmaların
derlendiği bir literatür taraması yapılmış, ardından havayolu ulaşımı sektöründe
faaliyet gösteren Türk Hava Yolları şirketi için bir firma değerleme uygulaması
anlatılmıştır. Söz konusu değerleme için yöntem olarak indirgenmiş serbest
nakit akım ve benzer şirket yöntemleri kullanılmış ve elde edilen sonuçlar
tutarlılık açısından kıyaslanmıştır. Değerleme hatasının minimum düzeyde
tutulması ve hissenin gerçeğe yakın değerine ulaşılması için, değerlemede
mümkün olduğunca çok yöntemin karşılaştırmalı olarak kullanılması
önerilmektedir. Ayrıca, sağlıklı bir değerleme sonucu elde edebilmek için,
değerlemede kullanılacak yöntemin seçim ve uygulama sürecinde firmanın ve
firmanın faaliyet gösterdiği sektörün spesifik özelliklerinin hassasiyetle
dikkate alınması gerektiği de düşünülmektedir.
İŞ YERİNDE MİZAH: BANKA ÇALIŞANLARININ METAFORİK ALGILARI
Authors: BAYRAKÇI Eylem
Published: December 2019

Mizahın insanın mutluluğuna ve refahına olumlu etkilerinin olduğu
uzun zamandır bilinmektedir. Birçok disiplin tarafından araştırma konusu
yapılan mizah, son zamanlarda örgütsel davranışlar alanında çalışan araştırmacıların
da dikkatini çekmiş ve iş yerinde mizah çalışma konusu yapılmaya başlanmıştır.
Bu çalışma banka çalışanlarının iş yerinde mizah algılarını metaforlar
aracılığıyla sunmayı amaçlamaktadır. Bu amaçla 36 banka çalışanından elde
edilen verilerin tümevarımsal içerik analizi sonucunda iş yerinde mizah ile
ilgili farklı bakış açıları belirlenmiştir. Buna göre, sağlık çağrışımı yapan
ilaç ve doktor metaforlarının sıklıkla kullanıldığı, mizahın iş yerinde
iyileştirici, tedavi edici gücü olan bir örgütsel unsur olarak algılandığı
görülmüştür. Bunun yanısıra, yine sıklıkla ifade edilen ve doğa çağrışımı
yapan, güneş, hayat, gökkuşağı gibi metaforlar ve besin çağrışımı yapan, tuz,
tatlı, et gibi metaforlar, iş yerinde mizahın örgüt üyesinin yaşamını
sürdürebilmesi için zorunlu bir ihtiyaç olarak algılandığını göstermiştir.
Üretilen bu metaforlar için sunulan gerekçeler ve metaforların mantıksal
dayanakları ise mizah kuramları kapsamında değerlendirilerek mizahın çoğunlukla
Rahatlama kuramı bağlamında algılandığı, bunun yanısıra Uyumsuzluk kuramını
çağrıştıran dayanakların da olduğu tespit edilmiştir. Çalışma grubundan elde
edilen veriler içinde Üstünlük kuramını ifade eden metafor gerekçesi ve
dayanağı betimlenmemiştir.
QUANTITATIVE AND QUALITATIVE INDICATORS OF SOCIAL NETWORK TRAFFIC ON THE SITE OF THE DIVISION OF SPSTL SB RAS IN 2015–2017
Authors: Komarov S. Yu.
Published: December 2019

The author examines quantitative and qualitative indicators of the external traffic from social networks to the website of SPSTL SB RAS Division. Based on the developed methodology for evaluating data from web analytics systems, conclusions about the significance of the considered social networks and the admissibility of promoting the resources of SPSL SB RAS Division into them are made.
Physicochemical Quality of Water and Health Risks Associated with the Consumption of the Extant African Lung Fish (Protopterus annectens) from Nyabarongo and Nyabugogo Rivers, Rwanda
Authors: Omara Timothy , Nteziyaremye Papias , Akaganyira Solomon , Opio Dickens Waswa , Karanja Lucy Nyambura , Nyangena Decrah Moraa , Kiptui Betty Jematia , Ogwang Remish , Epiaka Stephen Mark , Jepchirchir Abigael , Maiyo Alfayo
Published: December 2019

Water is an indispensable natural resource that is often prodigiously threatened by anthropomorphic activities. This study evaluated the physicochemical properties of water and selected heavy metals in edible muscles of a piscivorous fish (Protopterus annectens) from Nyabarongo and Nyabugogo rivers of Rwanda. Edibility health risk was evaluated using the target hazard quotient method. Water samples were taken in triplicate from Ruliba station and Kirinda bridge on Nyabarongo river and Giticyinyoni on Nyabugogo river. Fish samples were obtained from the sampling stations on Nyabarongo river. All samples were analyzed following standard methods and analytical results indicated that the average temperature, pH, total dissolved solids and electrolytic conductivity of water from the rivers were within WHO acceptable limits. The statistical mean concentrations of the ionic components of the water samples were 1.61 ± 0.03, 0.53 ± 0.002, 0.24 ± 0.02 and 0.051 ± 0.01 mg/L for Fe, Mn, Cu and Pb respectively at Ruliba station and 0.63 ± 0.02, 0.02 ± 0.002, 0.09 ± 0.01, 0.06 ± 0.002 and 0.75 ± 0.02 mg/L for Fe, Mn, Zn, Cr and Pb respectively at Kirinda bridge. Water from Giticyinyoni had 1.57 ± 0.02, 0.49 ± 0.03, 0.29 ± 0.058, 0.43 ± 0.058, 0.15 ± 0.00 and 0.59 ± 0.058 mg/L of Fe, Mn, Cu, Zn, Cr and Pb respectively. Zinc, Cu, Cr and Cd were below detection limits in samples from Ruliba station and Kirinda bridge (Nyabarongo river). Edible muscles of P. annectens from Nyabarongo river contained 272.8 ± 0.36, 292.2 ± 0.25, 8.8 ± 0.36, 135.2 ± 0.15, 148.0 ± 0.21 and 432. 0 ± 0.50 mgkg-1 for Fe, Mn, Cu, Zn, Cr and Pb at Ruliba station and 336.0 ± 0.70, 302.6 ± 1.22, 6.4 ± 0.26, 44.7 ± 0.20, 138.2 ± 0.17 and 302.4 ± 1.50 mgkg-1 for Fe, Mn, Cu, Zn, Cr and Pb respectively at Kirinda bridge. Health risk assessment indicated that consumption of the edible muscles of P. annectens may lead to deleterious health effects as reflected by values of target hazard quotients being greater than one. Therefore, the Rwandese government should lay strategies to reduce pollution of the rivers. Further research should evaluate the heavy metal content of metabolically active organs of P. annectens from Nyabarongo river as well as the microbiological profile of water from the rivers.
Requirement Change Management Techniques in Software Systems
Authors: Sirshar Mehreen , Ejaz Ghanwa , Mumtaz Maria
Published: December 2019

During software development requirement gathering is an important phase. Requirements are the basis of software development. The success or failure of any software depends upon level of understanding developed in requirements. During software development requirements keeps on changing due to different reasons. Hence requirements are such a critical phase that leads to the total project failure. So, to understand the impacts and to identify the conflicts with existing requirements, it is important to manage and analyze the requirements well. Requirement change management is the interest of this paper. Different requirement change management techniques has been discussed in this paper and analyzed them well and finally conclude the results accordingly.
A Unique “Reverse” Crescent Fragment in an Anterior-Posterior Compression Fracture
Authors: Montgomery Tyler P. , Sheppard Evan , Quade Jonathan H.
Published: December 2019

Case:

We describe a patient with an anterior-posterior compression type pelvic fracture sustained after a motorcycle crash, with pubic symphysis disruption and a “reverse” crescent fragment. The injury force ruptured the anterior sacroiliac ligaments and travelled posterior medially, creating a complete Denis zone 2 sacral fracture, rather than rupturing the posterior sacroiliac ligaments as would be expected. The patient underwent open reduction and internal fixation of the pubic symphysis and closed reduction and percutaneous pinning of the right sacroiliac joint.

Conclusions:

This case presents a unique “reverse” crescent fragment not previously described in the literature as an anterior-posterior compression type III variant.
Irreducible Knee Dislocation Associated With a Tertiary Gastrocnemius Head
Authors: Price Ryan C. , Shultz Christopher , Richter Dustin L. , Veitch Andrew , Schenck Robert C.
Published: December 2019

Case:

A 43-year-old man suffered an irreducible posterolateral knee dislocation while snowboarding with associated tears of the anterior cruciate, posterior cruciate, medial collateral, and posterolateral corner ligaments. Two closed reduction attempts failed, and magnetic resonance imaging revealed incarcerated soft tissue from a tertiary gastrocnemius muscle head. The patient underwent open reduction and repair/reconstruction of his multiligamentous knee injury. At the 6-year follow-up, the patient did not have pain or instability and returned to recreational activities.

Conclusions:

This case demonstrates that a tertiary gastrocnemius muscle head, the most common anatomical variation, may complicate the closed reduction of an irreducible posterolateral knee dislocation.