bluuebunny/crossref_metadata_2025 huggingface dataset:
Perspectives of Service Providers on Aftercare Service Provision for Persons with Substance Use Disorders at a Rural District in South Africa.
Authors: Mpanza December Mandlenkosi , Govender Pragashnie , Voce Anna
Published: October 2021

Background: Provision of aftercare services for persons with substance use disorders (PWSUD) within a rural context is typically met with various intersecting challenges, including unclear policy implications and lack of resources. In the South African context, service providers are expected to provide aftercare services that should achieve successful reintegration of persons with PWSUD into society, the workforce, family and community life as mandated by Act No. 70 of 2008, despite population diversity. Little has been established on the provision of aftercare services in South Africa and specifically within a rural context. This article explores the perspectives of service providers in aftercare service provision for PWSUD in a rural district.Methods: A qualitative exploratory study design was conducted in a rural district in South Africa using semi-structured interviews and focus group discussions with forty-six service providers from governmental and non-governmental institutions, ranging from implementation to policy level of service provision. Data were analyzed thematically using a deductive approach. Codes were predetermined from the questions and the aims and objectives of the study used Beer’s Viable Systems Model as a theoretical framework. NVivo Pro 12 qualitative data analysis software guided the organization and further analysis of the data.Results: Four themes emanated from the data sets. Theme 1 on reflections of the interactional state of aftercare services and program content identified the successes and inadequacies of aftercare interventions including relevant recommendations for aftercare services. Themes 2, 3, and 4 demonstrate reflections of service provision from implementation to policy level, namely, identifying existing barriers to aftercare service provision, situating systemic enablers to aftercare service provision, and associated aftercare system recommendations. Conclusions: The intersecting systemic complexities of providing aftercare services in a rural context in South Africa was evident. There existed minimal enablers for service provision in this rural district. Service providers are confronted with numerous systemic barriers at all levels of service provision. To strengthen the aftercare system, policies with enforcement of aftercare services are required. Moreover, a model of aftercare that is integrated into the existing services, family centered, sensitive to the rural context and one that encourages the collaboration of stakeholders could also strengthen and sustain the aftercare system and service provision.
Impact of Age at Onset on Symptom Profiles, Treatment Characteristics and Health-Related Quality of Life in Parkinson’s Disease
Authors: Odin Per , Norlin Jenny , Kellerborg Klas , Raket Lars , Martinez-Martin Pablo , Oudin Daniel
Published: October 2021

Parkinson’s disease (PD) is typically considered an age-related disease, but the age at disease onset can vary by decades between patients. Aging and aging-associated diseases can affect the movement system independently of PD, and advanced age has previously been proposed to be associated with a more severe PD phenotype with accelerated progression. In this work, we investigated how interactions between PD progression and aging affect a wide range of outcomes related to PD motor and nonmotor symptoms as well as Health Related Quality of Life (HRQoL) and treatment characteristics. This population-based cohort study is based on 1436 PD patients from southern Sweden followed longitudinally for up to approximately 7.5 years from enrollment. Higher age at onset was generally associated with faster progression of motor symptoms, with a notable exception of dyskinesia and other levodopa-associated motor fluctuations that had less severe trajectories for patients with higher age at onset. Mixed results were observed for emergence of non-motor symptoms, while higher age at onset was generally associated with worse HRQoL trajectories. Accounting for these identified age-associated differences in disease progression could positively impact patient management and drug development efforts.
Photonic Reservoir Computing for Real-Time Respiratory Motion Prediction
Authors: Liang Zhizhuo , Zhang Meng , Shi Chengyu , Huang Z. Rena
Published: October 2021

The application of reservoir computing (RC) is for the first time studied in a class of forecasting tasks in which signals are under random physical perturbations, meaning that the data-baring waveform distortions are versatile, and the process is not repeatable. Tumor movement caused by respiratory motion is such a problem and real-time prediction of tumor motion is required by the clinical radiotherapy. In this work, a true-time delay (TTD) respiration monitor based on photonic RC with adjustable nodes connection is developed specifically for this task. A breathing data set from a total of 76 patients with breathing speeds ranging from 3 to 20 breath per minute (BPM) are studied. A double-sliding window technology is demonstrated to enable the real-time establishment of an individually trained model for each patient and the real-time processing of live-streamed tumor position data. Motion prediction of look-ahead times of 66.6 ms, 166.6 ms and 333 ms are investigated. With a 333 ms look-ahead time, the real-time RC model achieves an average normalized mean square error (NMSE) of 0.0246, an average mean absolute error (MAE) of 0.338 mm, an average therapeutic beam exposure efficiency of 94.14% for an absolute error (AE) < 1mm and 99.89% for AE < 3mm. This study demonstrates that real-time RC is an efficient computing framework for high precision respiratory motion prediction.
Comparison of Urinary Adiponectin in the Presence of Metabolic Syndrome in Peri- and Postmenopausal Women
Authors: Vichinsartvichai Patsama , Teeramara Rattana , Jirasawas Titima , Sakoonwatanyoo Prirayapak
Published: October 2021

Objectives
To find the association between urinary adiponectin and metabolic syndrome (MetS) in peri- and postmenopausal women and its potential application as a noninvasive screening for MetS.
Methods
A cross-sectional study was conducted in healthy peri- and postmenopausal women (defined by STRAW+10 staging) age at least 40 years who attended annual checkup or menopause clinic were recruited. Baseline demographic data, MENQOL, anthropometric measurements, blood pressure, laboratory (FBS, total cholesterol, HDL-C, LDL-C, TG) and urinary adiponectin were collected. The MetS was diagnosed according to JIS 2009.
Results
290 peri- and postmenopausal women had participated. The prevalence of Mets among our participants was 18%. Urinary adiponectin levels were similar in peri- and postmenopausal women with and without MetS (2.6±2.2 vs 2.3±1.9 ng/mL, respectively, P = 0.55). Urinary adiponectin provides no diagnostic value for MetS (AUC = 0.516).
Conclusions
Urinary adiponectin has no role in screening and diagnosis of MetS in peri- and postmenopausal women. The quest toward noninvasive screening for MetS is still going on.
Coal Dust Exposure Triggers Heterogeneity of Transcriptional Profiles in Mouse Pneumoconiosis and Vitamin D Remedies
Authors: Mu Min , Li Bing , Zou Yuanjie , Wang Wenyang , Cao Hangbing , Zhang Yajun , Sun Qixian , Chen Haoming , Ge Deyong , Tao Huihui , Hu Dong , Yuan Liang , Tao Xinrong , Wang Jianhua
Published: October 2021

Background: Coal dust particles (CDP), an inevitable by-product of coal mining for the environment, mainly causes coal workers’ pneumoconiosis (CWP). Long-term exposure to coal dust leads to a complex alternation of biological processes during regeneration and repair in the healing lung. However, the cellular and molecular mechanism of abnormal homeostasis in lung tissue are not explicit. Methods: This study mainly investigated the pulmonary toxicity of respirable-sized CDP in mice using unbiased single-cell RNA sequencing. CDP (less than 5μm) collected from the coal mine was analyzed by Scanning Electron Microscope (SEM) and Mass Spectrometer. In addition, western blotting, Elisa, QPCR was used to detect gene expression at mRNA or protein levels. Pathological analysis including HE staining, Masson staining, immunohistochemistry, and immunofluorescence staining were performed to characterize the structure and functional alternation in the pneumoconiosis mouse and verify the reliability of single-cell sequencing results.Results: SEM image and Mass Spectrometer analysis showed that coal dust particles generated during coal mine production have been crushed and screened with a diameter of less than 5 µm and contained less than 10% silica. Dust can intranasally enter the alveoli in mice. Compared with the control group, alveolar epithelial cells and macrophages showed apparent heterogeneity after long-term exposure to CDP. Alveolar structure and pulmonary microenvironment were destroyed, leading to pneumoconiosis after coal dust stimulation. A distinct abnormally increased 39 population of alveolar type 2 epithelial cells (AT2) was classified with a highly active state but reducing the antimicrobial-related protein expression of LYZ and Chia1 after CDP exposure. Unique 40 inflammatory factors and signaling pathways further characterized critical signal exchanges between epithelial cells and macrophages. Apoptosis, autophagy and necrosis pathways were activated. A new subset of macrophages with M2-type polarization double expressed MLPH+/CD206+ was found in mice having pneumoconiosis but markedly decreased after the vitamin D treatment. Activated MLPH+/CD206+ M2 macrophages secreted TGF-β1 and are sensitive to vitamin D treatment. Beclin1, LC3B, LAMP2, TGF-ß, and MLPH were up-regulated, promoting autophagy and pulmonary fibrosis. Vitamin D supplements can reduce the cytotoxicity induced by CDP. This study first reconstructed the pathologic progression and transcriptome landscape of coal-pneumoconiosis and the therapeutic opportunity of vitamin D in mice.
Family With Sequence Similarity 46 Member A Confers Chemo-Resistance to Ovarian Carcinoma via TGF-β/Smad2 Signaling
Authors: Liang Suiying , Liu Yueyang , He Jianhui , Gao Tian , Li Lanying , He Shanyang
Published: October 2021

Purpose: Ovarian cancer is the most lethal malignancy with depressive 5-year survival rate, mainly due to patients with advanced stages experience tumor recurrence and resistance to the current chemotherapeutic agents. Thus, discovering the underlying molecular mechanisms involved in chemo-resistance is crucial for management of treatment to improve therapeutic outcomes. Methods: The protein and mRNA expression of FAM46A in ovarian cancer cell lines and patient tissues were determined using Real-time PCR and Western blot and IHC respectively. Functional assays, such as MTT, FACS assay used to determine the oncogenic role of FAM46A in human ovarian cancer progression. Furthermore, western blotting and luciferase assay were used to determine the mechanism of FAM46A promotes chemoresistance in ovarian cancer cells. Results: In the current study, we found overexpression of FAM46A expression in ovarian cancer patients demonstrated an aggressive phenotype and poor prognosis. Furthermore, FAM46A overexpression in ovarian cancer cells demonstrated higher CDDP resistance ability; however, inhibition of FAM46A sensitized ovarian cancer cell lines to CDDP cytotoxicity both in vitro and in vivo. Mechanically, upregulation of FAM46A activated transforming growth factor-β (TGF-β)/Smad signaling and upregulated the levels of nuclear Smad2. Conclusions: Taken together, our results highlight the important oncogenic role of FAM46A in ovarian cancer progression and might provide a potential clinical target for patients with chemoresistant ovarian cancer.
Improving Maggot Therapy: Mass Rearing And Molecular Identification of Lucilia Sericata (Meigen, 1826) Larvae In Maggotarium, School of Health, Shiraz
Authors: Bagheri Masoumeh , Alipour Hamzeh , Shahriari-Namadi Marziea , Malekpour Seyed Hossein , Raz Abasali
Published: October 2021

Background: Lucilia sericata as a member of the family Caliphoridae has a complete metamorphosis. They feed on on necrotic and livingtissues as necrophage species. Sterile larvae of this species has been utilized to heal wounds for decades. The aim of this study were to establish the breeding and identifying of the L.sericata species based on morphological and molecular techniques. Freshly harvested grown under standard conditions in the maggotarium of Health School , Shiraz of. They were screened using conventional morphology, then Primarily, different parameters related to larvae were measured morphologically. Subsequently, DNA was extracted and molecular marker of cytochrome C oxidase (co1) was amplified using PCR assay and sequence data were used for molecular and phylogenetic analysis. Result: In this study, 50 samples which grown collected from maggotarium were identified as L. sericata using morphological and molecular methods. This species was placed in a separate clade of the phylogenetic tree based on COI nucleotide sequences of different species and has a phylogenetic similarity to Lucilia purpurascens species of flies. Conclusion: Larval therapy especially by Lucilia sericata is a promising strategy in wound healing. Due to the importance of larval species in this technique, having an accurate knowledge of aplicable species leads to a proper larval therapy. Increasing in resistance of wounds to antibiotics has led to the use of maggot therapy in the past. Larval therapy is a low-cost, non-surgical way to remove dead tissue (predecessors and necrosis) in chronic wounds and prevents excessive soft tissue damage and infection from reaching the underlying tissues and bones (osteomyelitis). Maggot therapy is a promising way to prevent amputation, especially in people with diabetes.
T2/FLAIR Abnormity Could Be the Early Sign of Glioblastoma Dissemination
Authors: Li Mingxiao , Huang Wei , Chen Hongyan , Jiang Haihui , Yang Chuanwei , Shen Shaoping , Zhang Xiaokang , Zhao Xuzhe , Zhu Qinghui , Li Ming , Dong Gehong , Cui Yong , Ren Xiaohui , Lin Song
Published: October 2021

PurposeNewly emerged or constantly enlarged contrast-enhancing (CE) instead of T2/FLAIR lesions were the necessary sign for the diagnosis of glioblastoma (GBM) progression. This study aimed to investigate whether the T2/FLAIR abnormal transformation could predict and assess progression for GBMs, especially for dissemination. MethodsA consecutive cohort of 246 de novo GBM with regular follow-up and sufficient radiological data were included in this study. The series of T2/FLAIR, T1CE images were retrospectively reviewed. The patients were separated into T2/FLAIR and T1CE discordant and accordant subgroups based on the initial progression images.ResultsA total of 170 qualified patients were finally analyzed. The incidence of discordant T2/FLAIR and T1CE images was 25.9% (44/170). The median time of T2/FLAIR indicated tumor progression was 119.5 days (ranging from 57 days-unreached) prior to T1CE. Nearly half of patients (20/44, 45.5%) in discordant subgroup suffered from tumor dissemination, substantially higher than accordant patients (23/126, 20.6%, P<0.001). The median time to progression (TTP), post-progression survival (PPS), and overall survival (OS) were not statistically different (all P>0.05) between discordant and accordant patients. Conclusions T2/FLAIR abnormity could be the early sign of GBM progression, especially for newly emerged lesions disseminated from the primary cavity. Physicians should cast more attention on the dynamic change of T2/FLAIR images for progression assessment and subsequent clinical decision-making.
Smoothing age/time structure of HIV prevalence, for optimal use in synthetic cohort based incidence estimation
Authors: Mhlanga Laurette , Eduard Grebe , Welte Alex
Published: October 2021

BackgroundPopulation-based surveys which ascertain HIV status are conducted in heavily affected countries, with the estimation of incidence being a primary goal. Numerous methods exist under the umbrella of ‘synthetic cohort analysis’, by which we mean estimating incidence from the age/time structure of prevalence (given knowledge on mortality). However, not enough attention has been given to how serostatus data is ‘smoothed’ into a time/age-dependent prevalence, so as to optimise the estimation of incidence.MethodsTo support this and other related investigations, we developed a comprehensive simulation environment in which we simulate age/time structured SI type epidemics and surveys. Scenarios are flexibly defined by demographic rates (fertility, incidence and mortality – dependent, as appropriate, on age, time, and time-since-infection) without any reference to underlying causative processes/parameters. Primarily using 1) a simulated epidemiological scenario inspired by what is seen in the hyper-endemic HIV affected regions, and 2) pairs of cross-sectional surveys, we explored A) options for extracting the age/time structure of prevalence so as to optimise the use of the formal incidence estimation framework of Mahiane et al, and B) aspects of survey design such as the interaction of epidemic details, sample-size/sampling-density and inter-survey interval.ResultsMuch as in our companion piece which crucially investigated the use of ‘recent infection’ (whereas the present analysis hinges fundamentally on the estimation of the prevalence gradient) we propose a ‘one size fits most’ process for conducting ‘synthetic cohort’ analyses of large population survey data sets, for HIV incidence estimation: fitting a generalised linear model for prevalence, separately for each age/time point where an incidence estimate is desired, using a ‘moving window’ data inclusion rule. Overall, even in very high incidence settings, sampling density requirements are onerous.ConclusionThe general default approach we propose for fitting HIV prevalence to data as a function of age and time appears to be broadly stable over various epidemiological stages. Particular scenarios of interest, and the applicable options for survey design and analysis, can readily be more closely investigated using our approach. We note that it is often unrealistic to expect even large household based surveys to provide meaningful incidence estimates outside of priority groups like young women, where incidence is often particularly high.
New species and additional records of Leptusa from the Palaearctic region, with a focus on the faunas of China and the Caucasus region (Coleoptera: Staphylinidae: Aleocharinae)
Authors: Assing Volker
Published: October 2021

Eleven species of Leptusa Kraatz, 1858 are described and illustrated: Leptusa (Aphaireleptusa) excisa spec. nov. (China: Shaanxi: Qinling Shan); L. (A.) grandipennis spec. nov. (China: Sichuan: Songpan env.); L. (A.) gonggana spec. nov. (China: Sichuan: Gongga Shan); L. (A.) habana spec. nov. (China: Yunnan: Haba Shan); L. (A.) auriculata spec. nov. (China: Yunnan: Diancang Shan); L. (Drepanoleptusa) emeiana spec. nov. (China: Sichuan: Emei Shan); L. (D.) jizuica spec. nov. (China: Yunnan: Jizu Shan); L. (D.) desculpens spec. nov. (China: Yunnan: Dawei Shan); L. (Chondrelytropisalia) procera spec. nov. (China: Sichuan: Songpan env.); L. (Yunnaleptusa) monscangi spec. nov. (China: Yunnan: Diancang Shan); L. (Chondrelytropisalia) pathibarana spec. nov. (Nepal: Taplejung district). One synonymy is proposed: Leptusa (Drepanoleptusa) emplenotoides Assing, 2006 = Leptusa (Aphaireleptusa) zhongdianensis Pace, 2010, syn. nov. Leptusa jinfomontis Pace, 2001 (previously in Nesopisalia Pace, 1992) and L. calliceroides Assing, 2004 (previously incertae sedis) are moved to the subgenus Drepanoleptusa Pace, 1982. An updated catalogue of the Leptusa species recorded from China, Taiwan, and Hong Kong is provided. The Leptusa fauna of this region now includes 73 species and three subspecies in twelve subgenera. Additional records of 22 previously named species are reported from China (eleven species), the Caucasus region (eight), Japan (two), and South Korea (one), among them several new country and regional records. Leptusa is now represented in the Palaearctic region by 418 species and 74 subspecies in 71 subgenera.

Taxonomic acts

Leptusa excisa spec. nov. – urn:lsid:zoobank.org:act:963E5B3D-F42E-411C-A6A9-F57EBCCA00E5Leptusa grandipennis spec. nov. – urn:lsid:zoobank.org:act:476EFE09-A2F0-4227-8F55-AEC9D658E159Leptusa gonggana spec. nov. – urn:lsid:zoobank.org:act:063A3FD3-32D8-4F48-AABA-5AB12CF1A686Leptusa habana spec. nov. – urn:lsid:zoobank.org:act:217C5415-9901-4E13-8DD8-3F8AEA4CC8C1Leptusa auriculata spec. nov. – urn:lsid:zoobank.org:act:1812AE30-52FF-498D-B8C2-D600DCAB2724Leptusa emeiana spec. nov. – urn:lsid:zoobank.org:act:963E5B3D-F42E-411C-A6A9-F57EBCCA00E5Leptusa jizuica spec. nov. – urn:lsid:zoobank.org:act:D1844B8D-2B3B-4388-933D-F2F98883B6A6Leptusa desculpens spec. nov. – urn:lsid:zoobank.org:act:A3342BAF-F31E-43E6-9636-8250A85FBD97Leptusa procera spec. nov. – urn:lsid:zoobank.org:act:C3881039-6537-452F-974C-48BDAFD02762Leptusa monscangi spec. nov. – urn:lsid:zoobank.org:act:2B2ECDE0-93FD-42BB-BF27-6D7C7B8E38BCLeptusa pathibarana spec. nov. – urn:lsid:zoobank.org:act:ED968EFF-8133-4318-992C-A4D401C04ADB
Sexueller Kindesmissbrauch durch Frauen
Authors:   , Knauer Monika
Published: October 2021

Bisherige Forschungsergebnisse zeigen, dass auch Frauen sexuellen Kindesmissbrauch begehen und somit eine potentielle Gefahr für das Kindeswohl darstellen können. Aus Deutschland liegen bisher nur regionale oder Studien mit geringer Stichprobengröße vor. Die vorliegende Studie verfolgt das Ziel, eine umfassende Bestandserhebung des sexuellen Kindesmissbrauchs durch Frauen in Deutschland zu dokumentieren. Im Rahmen der vorliegenden Untersuchung wurden zum ersten Mal bundesweit Strafakten von 465 pädokriminellen Frauen ausgewertet, die in den letzten 30 Jahren nach §§174, 176, 180 oder 182 des StGB verurteilt wurden. Die standardisierte Analyse umfasst 185 Variablen und 54 selbst definierte Skalen. Die Ergebnisse zeigen, dass eine pädokriminelle Frau durchschnittlich 33 Jahre alt ist, zumeist in einer Ehe in einer Kleinstadt lebt und häufig keiner beruflichen Tätigkeit nachgeht. Sie ist eine Mittäterin, handelt überwiegend aus Abhängigkeit zu ihrem männlichen Komplizen heraus, zu dem sie eine intime Beziehung pflegt und missbraucht mehrheitlich weibliche Opfer (Verhältnis fast 2:1). Beinahe die Hälfte der 614 Opfer, zu denen Informationen vorlagen, waren leibliche Kinder der Täterinnen und rund jedes sechste Kind stammte vom männlichen Mittäter.
Dentofacial changes following treatment with a fixed functional appliance and their three-dimensional effects on the upper airway
Authors: Abdalla Yousef , Kiliaridis Stavros , Sonnesen Liselotte
Published: October 2021

Background

Proposed skeletal changes achieved by functional appliances (FA) with reference to stable structures (structural method) have received relatively little attention compared to conventional cephalometric measurements (conventional method). Using the two methods, the aims of this study were to (1) determine the skeletal changes as a result of FA treatment; and (2) identify the skeletal changes associated with upper-airway volume and minimum cross-sectional area (MCA).

Methods

Pre- and post-treatment CBCT scans were selected from 73 FA treated children (37 girls and 36 boys; mean age 12.0 years) and 73 children as a control group (matched for chronological age, skeletal age, gender, and mandibular inclination) who received orthodontic treatment using only fixed appliances (no FA). Skeletal, upper-airway volume, and MCA changes were analysed by applying both structural and conventional methods.

Results

The FA group had significant skeletal effects compared with the control group (both methods; p = 0.04 – p < 0.001). The horizontal displacement of pogonion (both methods) and the hyoid bone, together with a forward mandibular rotation (structural method), had positive effects on upper-airway volume and MCA (p < 0.05).

Conclusions

The horizontal changes in pogonion (both methods) and the hyoid bone, as well as a forward mandibular rotation (structural method), have a strong association with changes in the upper airway. The conventional method underestimates FA treatment effects. These results may influence the management of growing class II patients with compromised upper airways.
Pyradoketosite, a new, unexpected, polymorph of Ag3SbS3 from the Monte Arsiccio mine (Apuan Alps, Tuscany, Italy)
Authors: Biagioni Cristian , Bindi Luca , Moëlo Yves , Stanley Christopher J. , Zaccarini Federica
Published: October 2021

Although everything seemed clear about the Ag-Sb-S compounds belonging to one of the more deeply studied experimental systems, nature allowed us to discover a new polymorph of Ag3SbS3, which could represent a compound for assessing new technological potentialities. The new mineral species pyradoketosite, Ag3SbS3 (IMA 2019-132), was discovered in the pyrite + baryte + iron oxide ore deposit of the Monte Arsiccio mine, Apuan Alps, Tuscany, Italy. It occurs as brittle orange acicular crystals, up to 200 μm in length and 25 μm in thickness, with adamantine luster. Under reflected light, pyradoketosite is slightly bluish-gray, with abundant orange internal reflections. Bireflectance is weak, and anisotropism was not observed, being masked by abundant internal reflections. Minimum and maximum reflectance data for the wavelengths recommended by the Commission on Ore Mineralogy [Rmin/Rmax (%) (λ, nm)] are 32.8/32.9 (470), 30.2/30.7 (546), 29.0/29.6 (589), and 27.5/28.4 (650). Electron microprobe analysis gave (mean of 6 spot analyses, in wt%): Ag 59.81, Sb 22.63, S 17.78, total 100.22. On the basis of (Ag+Sb) = 4 atoms per formula unit, the empirical formula of pyradoketosite is Ag2.996(11)Sb1.004(11)S2.996(15). Pyradoketosite is monoclinic, space group P21/n, with a = 13.7510(15), b = 6.9350(6), c = 19.555(2) Å, β = 94.807(4)°, V = 1858.3(3) Å3, Z = 12. The crystal structure was solved and refined to R1 = 0.063 on the basis of 2682 unique reflections with Fo > 4σ(Fo) and 191 refined parameters. The structure of pyradoketosite can be described as formed by the alternation of {101} layers: an Sb-rich layer, Sb3AgS3, and two distinct Ag8S6 layers. This layered organization allows identifying structural relationships with the wittichenite-skinnerite pair. Pyradoketosite is associated with pyrargyrite, tetrahedrite-(Hg), valentinite, and probable pyrostilpnite in baryte + dolomite + quartz veins embedded in metadolostone. Its name derives from the old Greek words “πυρ” (fire) and “άδόκητος” (unforeseen), because of the unexpected occurrence of this third polymorph of the compound Ag3SbS3.
LEARNING MANAGEMENT DURING THE COVID-19 PANDEMIC AT THE BUSTANUL ULUM TARBIYAH SCHOOL OF SCIENCE, CENTRAL LAMPUNG
Authors:   Post-Graduate Program of Islamic Education Management Study Program, Raden Intan State Islamic University of Lampung, Indonesia., Maarif Samsul , Anwar Syaiful ,   Post-Graduate Program of Islamic Education Management Study Program, Raden Intan State Islamic University of Lampung, Indonesia., Masykur Rubhan ,   Post-Graduate Program of Islamic Education Management Study Program, Raden Intan State Islamic University of Lampung, Indonesia., Fauzanand Koderi Ahmad ,   Post-Graduate Program of Islamic Education Management Study Program, Raden Intan State Islamic University of Lampung, Indonesia.
Published: October 2021

This study aimed to describe the learning management during the Covid-19 pandemic at the STIT Bustanul Ulum Central Lampung. This study employed the qualitative method with a descriptive approach. The researchers had collected the data by documenting books, dissertations, theses, magazines, journals, or others that discussed the research problems. Planning for online learning during Covid-19 at the STIT Bustanul Ulum Central Lampung consisted of compiling a syllabus and lesson plan containing elements of Covid-19 with a simplified curriculum and adapted to online methods and media. There were three main activities in implementing online learning during covid-19 at the STIT Bustanul Ulum Central Lampung. These activities were preliminary activities, core activities, and closing activities. The online learning evaluation during Covid-19 at the STIT Bustanul Ulum Central Lampung consisted of cognitive, affective, and psychomotor assessments.
FOLK ANTIDIABETIC PLANTS OF ASSAM: A SURVEY ON THEIR REPORTED ACTIVITY AND FUTURE POTENTIAL
Authors:   Faculty of Pharmaceutical Science, Assam Down Town University, Panikhaiti, Guwahati, Assam., Borsaikia Ansumita , Sen Saikat ,   Faculty of Pharmaceutical Science, Assam Down Town University, Panikhaiti, Guwahati, Assam., Gogoi Pal ,   Faculty of Pharmaceutical Science, Assam Down Town University, Panikhaiti, Guwahati, Assam., Deka Pritam ,   Faculty of Pharmaceutical Science, Assam Down Town University, Panikhaiti, Guwahati, Assam., Kumar Dey Biplab ,   Faculty of Pharmaceutical Science, Assam Down Town University, Panikhaiti, Guwahati, Assam.
Published: October 2021

Assam is a state in Indias north-eastern region, known for its lush floral and cultural diversity. We combed through the literature and discovered that about 117 Assamese plant species had been shown to have antidiabetic potential in preclinical studies. Diabetes, in its many forms, has been a long-standing problem for doctors for decades. Many aspects of diabetes must be investigated, including the physiological actions of insulin and the different clinical features of the condition, such as tissue complications. Since diabetes is a lifestyle disease, careful care with regard to diet and anti-diabetic agents is essential. Herbal diabetes therapy is not a novel concept. Plants and plant extracts have been used to treat diabetes since 1550 B.C., with as many as 400 prescribed before the development of effective diabetes drugs earlier this century.
GROWTH AND YIELD RESPONSE OF PAK CHOI (BRASICCA RAPA) TO DIFFERENT FOLIAR FERTILIZERS UNDER PROTECTED CULTIVATION
Authors:   Philippine Crop Insurance Corporation., Ann G. Cantillo May , R. Molon SR. Cornelio ,   Laguna State Polytechnic University.
Published: October 2021

The experiment was conducted to determine the growth and yield response of pak choi (Brasiccarapa var. Chinkang Genghis Khan) to different foliar fertilizers (viz. vermitea, commercial foliar fertilizer, effective microorganisms [EM-1] and natural farming inputs [NFI]) under protected cultivation. It aimed to evaluate the influence of the different foliar fertilizers on pak choi in terms of growth characteristics, yield components, and pests and disease incidence. Similarly, to conclude which among the foliar fertilizers evaluated will be most the economical for pak choi production. The study was done in the DA-ATI IV-A and LSPU Organic Agriculture Learning Site in the Laguna State Polytechnic University, Siniloan, Laguna in December 2015 to February 2016. A total of 300 plants were used as experimental units in the study. Every treatment was replicated three times and each replication has 10 polyethylene bags planted with two plants each. Data was collected and analysed with the use of the Duncans Multiple Range Test (DMRT). Results revealed that the foliar fertilizers used have no remarkable effect on the weekly height, weekly growth rate, length of leaves, and shoot root ratio of pak choi. Nevertheless, commercial fertilizer significantly increased the mean number of leaves (7.53cm), width of leaves (15.10cm), economic and biological yields (105.10 grams and 106.88 grams, respectively) of pak choi compared with the rest of the treatments, except for vermitea which produced a comparable width of leaves (15.04cm). Also, a significantly lower number of the damaged leaves caused by looper (TrichoplusianiHÃ¼bner) was noted on plants treated with commercial foliar fertilizer (0.51 leaf per plant). The highest net income was obtained by commercial foliar fertilizer-treated plants, but plants treated with vermitea earned the highest return of investment (ROI). Therefore, the utilization of vermitea in pak choi production can reduce the cost of fertilizer and contribute to an economical production system under protected cultivation.
LINKING CORPORATE SOCIAL RESPONSIBILITY (CSR)PRACTICES TO SUSTAINABLE DEVELOPMENT GOALS (SDGS) IN INDIA
Authors: Dangi Thakur Geetanjali , Puntambekar G.L.
Published: October 2021

India is a vast country with huge size of population and half of the population is living under poverty & inequality. Indias big share of population is struggling for basic amenities and there is a need of collaborative efforts of both government and corporate sector. In India Sustainable Development Goals (here after SDGs) and Corporate social Responsibility (hereafter CSR) are the most powerful tools to deal with social issues. CSR seems like a powerful framework for corporate sector to engage in achieving SDGs to a certain extent. In 2015 India adopted the 17 sustainable development goals with 169 targets and in 2014 CSR policy came with social initiatives. The idea behind linking CSR & SDGs is the thematic social sectors included in both of them.The activities which are included in schedule VII of companies act having lot of overlap with the thematic areas of sustainable development goals and thats why there has seen tremendous potential of both tools to develop a model for sustainable growth. Till date from 2014 to 2020 corporate sector contributed Rs. 59,505 cr. in CSR activities which are directly related to SDGs. So, this paper focus on the concept of leveraging CSR practices because working on CSR practices will ultimately help in achieving SDGs to higher extent.
PROSPECTIVE STUDY OF BEDSIDE ASSESSMENT OF DIABETIC PERIPHERAL NEUROPATHY
Authors:   Associate Professor, Department of General Surgery, MIMER Medical College, Talegaon Dabhade, Pune., S. Khachane Tushar , Karandikar Sangram ,   Associate Professor, Department of General Surgery, Terna Medical College, Navi Mumbai.
Published: October 2021

Background: Diabetic peripheral sensorimotor neuropathy is one of the most prevalent neuropathic syndromes affecting around 50 % people with diabetes. Its development is gradual with subtle changes hence ignored. Early diagnosis using simple bedside tools is essential. Methods: The prospective study of evaluation of peripheral neuropathy in diabetes involved examination of 500 diabetic patients for neuropathy. Pinprick, vibration sensation, perception of 5.07 Semmes Weinstein monofilament and Achilles tendon reflex were examined and impairment noted. Results: 39 % patients had impairment of perception of Semmes Weinstein monofilament. Loss of pinprick sensation was found in 65.6 % in patients with diabetes for 5-10 years duration. Abnormal tendon reflex was seen in 64.2 % in patients with diabetes move than 10 years. Loss of Vibration (40.2 %), Wasting (16.6 %), loss of pinprick sensation (44.5%) and loss of abnormal tendon reflex (32.1 %) was found to be more common in type II diabetes. Conclusion: Sensorimotor peripheral neuropathy was more common in long standing diabetes mellitus especially with impaired glycaemic control and type II diabetes mellitus.
Remote sensing inversion characteristic and driving factor analysis of wetland evapotranspiration in the Sanmenxia Reservoir area, China
Authors: Wang Shiyan , Liu Chang , Tan Yiqian , Wang Jie , Du Fei , Han Zhen , Jiang Zhi , Wang Liang
Published: October 2021

Evapotranspiration in the hydrologic cycle realizes the energy and water transport in the atmosphere. Evapotranspiration differences concerning land-use types provide data for studying the evapotranspiration of river basins. To investigate the evapotranspiration in the reservoir under artificial regulation, we selected the river basin in the Sanmenxia Reservoir as the study area. Data sources are two-period Landsat8 OIL_TIRS remote sensing images during the growing season of wetland plants. Based on meteorological data in this river basin, we investigated the evapotranspiration differences of different land-use types using the Surface Energy Balance Algorithm for Land model. The FAO Penman–Monteith formula verified the remote sensing inversion results. Analysis shows that significant differences were manifested between wetland and non-wetland landscapes in evapotranspiration among different land-use types. Non-wetland landscapes accounted for about 97.23% of the river basin's total area, but their daily average evapotranspiration was only 7.26 mm/d. Those of wetland landscapes were 2.77% and 12.17 mm/d. In this river basin, the differences between the wetland and non-wetland landscapes in evapotranspiration are mainly associated with plant diversity, vegetation coverage and surface temperature (beyond other driving factors like meteorological and hydrological solar radiation factors).
Short-term exposure to benzalkonium chloride in bacteria from activated sludge alters the community diversity and the antibiotic resistance profile
Authors: Chacón Luz , Arias-Andres Maria , Mena Freylan , Rivera Luis , Hernández Lorena , Achi Rosario , Garcia Fernando , Rojas-Jimenez Keilor
Published: October 2021

The continuous introduction of cleaning products containing benzalkonium chloride (BAC) from household discharges can mold the microbial communities in wastewater treatment plants (WWTPs) in a way still poorly understood. In this study, we performed an in vitro exposure of activated sludge from a WWTP in Costa Rica to BAC, quantified the changes in intI1, sul2, and qacE/qacEΔ1 gene profiles, and determined alterations in the bacterial community composition. The analysis of the qPCR data revealed elevated charges of antibiotic resistance genes in the microbial community; after BAC's exposure, a significant increase in the qacE/qacEΔ1 gene, which is related to ammonium quaternary resistance, was observed. The 16S rRNA gene sequences’ analysis showed pronounced variations in the structure of the bacterial communities, including reduction of the alpha diversity values and an increase of the relative abundance of Alphaproteobacteria, particularly of Rhodospseudomonas and Rhodobacter. We confirmed that the microbial communities presented high resilience to BAC at the mg/mL concentration, probably due to constant exposure to this pollutant. They also presented antibiotic resistance-related genes with similar mechanisms to tolerate this substance. These mechanisms should be explored more thoroughly, especially in the context of high use of disinfectant.
Laboratory investigations on the quality of leak tests and visual inspections of wastewater connection pipes carried out by specialist contractors
Authors: Ulutaş S. , Wichern M. , Bosseler B.
Published: October 2021

In addition to stability and operational safety, leak tightness is the permanent functional objective of wastewater pipes. Tests to determine the tightness of wastewater pipes can in some cases produce results that are worthy of discussion. Therefore, laboratory tests were carried out by 29 specialist contractors to obtain results on the quality of leak tests and visual inspections of connection pipes. The results showed that different test errors can be observed for leak test methods (air overpressure, air underpressure and water pressure). However, only in the case of the water pressure tests did the observed test errors occasionally lead to incorrect test results, i.e. the ‘leaking pipe’ was tested as ‘test passed (tight)’. The investigations into the accuracy (trueness and precision) of the test methods showed that all test methods examined were sufficiently accurate to determine the tightness of the connection pipes. In general, correct test results were achieved if the expert testers did not make any serious test errors and the test equipment used functioned properly. In contrast, the investigations on the quality of visual inspection showed that the procedure is not sufficiently reliable to fulfil all normative requirements regarding damage detection and naming as well as damage classification.
Recent progress using membrane aerated biofilm reactors for wastewater treatment
Authors: He Huanqi , Wagner Brett M. , Carlson Avery L. , Yang Cheng , Daigger Glen T.
Published: October 2021

The membrane biofilm reactor (MBfR), which is based on the counter diffusion of the electron donors and acceptors into the biofilm, represents a novel technology for wastewater treatment. When process air or oxygen is supplied, the MBfR is known as the membrane aerated biofilm reactor (MABR), which has high oxygen transfer rate and efficiency, promoting microbial growth and activity within the biofilm. Over the past few decades, laboratory-scale studies have helped researchers and practitioners understand the relevance of influencing factors and biological transformations in MABRs. In recent years, pilot- to full-scale installations are increasing along with process modeling. The resulting accumulated knowledge has greatly improved understanding of the counter-diffusional biological process, with new challenges and opportunities arising. Therefore, it is crucial to provide new insights by conducting this review. This paper reviews wastewater treatment advancements using MABR technology, including design and operational considerations, microbial community ecology, and process modeling. Treatment performance of pilot- to full-scale MABRs for process intensification in existing facilities is assessed. This paper also reviews other emerging applications of MABRs, including sulfur recovery, industrial wastewater, and xenobiotics bioremediation, space-based wastewater treatment, and autotrophic nitrogen removal. In conclusion, commercial applications demonstrate that MABR technology is beneficial for pollutants (COD, N, P, xenobiotics) removal, resource recovery (e.g., sulfur), and N2O mitigation. Further research is needed to increase packing density while retaining efficient external mass transfer, understand the microbial interactions occurring, address existing assumptions to improve process modeling and control, and optimize the operational conditions with site-specific considerations.
Gênero feminino: identidade e estereótipo – Dilma Rousseff em seu primeiro mandato
Authors: Ferreira Dina Maria Martins , Pereira Dulce Valente
Published: October 2021

Neste artigo, buscamos analisar a identidade feminina em discursos de Dilma Rousseff, primeiro mandato, tendo em vista, de um lado, os estereótipos históricos da “feminilitude” que valorizam a falocracia, e, de outro, posições de “feminilitude” que valorizam a práxis do feminino, em posição feminista. Para tal, são levantados sentidos linguístico-discursivos com vistas não somente à reprodução de estereótipos históricos, mas também à contestação e ressignificação destes. Nossa análise linguísticodiscursiva prioriza macro-categorias: ethos discursivo, feminilidade e “feminilitude”, cujo propósito é identificar os performativos identitários da “feminilitude”, tais como legitimação e resistência frente a uma ordem social histórica falocrática. E diante desta trincheira, um ethos discursivo se configura por micro-categorias: ruptura, identificação, agenciamento, empoderamento e contestação. Mesmo diante deste quadro teóricocategorial, que privilegia as trincheiras de resistência às ações históricotradicionais, ainda verifica-se a ordem social e as ações históricotradicionais do falocrático.
Os processos de articulação de orações sob diferentes abordagens: um olhar para a hipotaxe adverbial
Authors: Ramos Marta Anísia Bezerra , Silva Camilo Rosa
Published: October 2021

Neste artigo, caracterizamosos processos de articulação oracional, em particular, o mecanismo referido por “hipotaxe adverbial”, enfatizando seu importante papel na organização da coerência textual. Nessa perspectiva, apresentamos uma visão panorâmica das diferentes abordagens sobre o tema, procurando mostrar que, enquanto a abordagem tradicional se centra na análise da sentença, os estudos funcionalistas ampliam esse enfoque,explorando outros níveis de análise além do sintático. Para explicação dos processos de articulação, trazemos, como ilustração, fragmentos de textos de teor argumentativo, e, a partir da observação de outros aspectos relacionados à organização textual, como a pontuação, ordem de ocorrência e relevância das informações, e também o vocabulário,enfatizamos a relação entre organização sintática e construção da textualidade. A partir daí, propomos uma atividade que conduz à reflexão em torno das escolhas dos usuários da língua. Nesteestudo, além da referência a gramáticos como Bechara(1999) e Perini(1996), reportamo-nos a autores funcionalistas, tais como Halliday(1985), Matthiessen e Thompson (1988), Lehmann (1988) e Hopper e Traugott (1993), dentre outros.
Correspondências entre amigos pernambucanos da primeira metade do século xx: tradição discursiva e ensino-correspondence
Authors: Silva Aldeir Gomes da , Gomes Valéria Severina
Published: October 2021

Neste trabalho, analisamos oito cartas de amigos, trocadas por missivistas pernambucanos, em diferentes condições de produção, na primeira metade do século XX. Temos por objetivo identificar os elementos constitutivos que especificam o subgênero carta de amigo; verificar os modos de dizer que se configuram como Tradição Discursiva; por fim, refletir sobre a importância desse conteúdo para os estudos linguísticos em sala de aula, através de atividades que envolvam as propostas dos PCNs: o trabalho com gêneros textuais e a análise linguística (AL). Para tanto, partimos das abordagens de Koch(1997), Oesterreicher (1997, 2006), Kabatek (2003, 2006), Souza (2012),Longhin (2014), Lopes e Gomes (2016), Marcuschi (2011) e Bezerra & Reinaldo (2013). Os resultados da investigação evidenciam a relação de proximidade entre os interlocutores manifesta por meio dos recursos linguístico-discursivos utilizados; os modos de dizer tradicionais na composição das cartas de amigo; e as possibilidades de transposição dos dados analisados para o ensino.
Análise da transitividade e da construção identitária no gênero discussion : uma abordagem sistêmico-funcional
Authors: Alves Ramalho Heryzânya , Cooper Jennifer Sarah
Published: October 2021

Este artigo pretende analisar aspectos da transitividade em exemplares do gênero discussion numa perspectiva sistêmico-funcional (HALLIDAY, 1994; HALLIDAY; MATTHIESSEN, 2014) com o intuito de observar de que forma as escolhas lexicogramaticais realizadas pelos autores dos textos auxiliam na construção identitária (IVANIČ,1998). Para esse fim, foram investigados três textos produzidos por alunos do curso de Conversação I em inglês do Instituto Ágora no segundo semestre de 2015 na UFRN. Os resultados da pesquisa apontam os processos materiais como mais recorrentes, pois foram utilizados para fundamentar argumentações e fazer recomendações, criando, assim, o perfil do autor que domina o assunto do qual discorre. Ainda, o uso recorrente de pronomes como we¸ us e our nos textos ajudam a construir uma identidade comunitária como estratégia para envolver o leitor e ganhar a sua adesão.