bluuebunny/crossref_metadata_2025 huggingface dataset:
Visualising phase change in a brushite-based calcium phosphate ceramic
Authors: Bannerman A. , Williams R. L. , Cox S. C. , Grover L. M.
Published: September 2016

The resorption of brushite-based bone cements has been shown to be highly unpredictable, with strong dependence on a number of conditions. One of the major factors is phase transformation, with change to more stable phases such as hydroxyapatite affecting the rate of resorption. Despite its importance, the analysis of phase transformation has been largely undertaken using methods that only detect crystalline composition and give no information on the spatial distribution of the phases. In this study confocal Raman microscopy was used to map cross-sections of brushite cylinders aged in Phosphate Buffered Saline, Foetal Bovine Serum, Dulbecco’s – Minimum Essential Medium (with and without serum). Image maps showed the importance of ageing medium on the phase composition throughout the ceramic structure. When aged without serum, there was dissolution of the brushite phase concomitant to the deposition of octacalcium phosphate (OCP) around the periphery of the sample. The deposition of OCP was detectable within five days and reduced the rate of brushite dissolution from the material. The use of serum, even at a concentration of 10vol% prevented phase transformation. This paper demonstrates the value of confocal Raman microscopy in monitoring phase change in biocements; it also demonstrates the problems with assessing material degradation in non-serum containing media.
M2BP inhibits HIV-1 virion production in a vimentin filaments-dependent manner
Authors: Wang Qin , Zhang Xiaolin , Han Yuling , Wang Xinlu , Gao Guangxia
Published: September 2016

M2BP (also called 90K) is an interferon-stimulated gene product that is upregulated in HIV-1 infection. A recent study revealed that M2BP reduces the infectivity of HIV-1 by inhibiting the processing of the viral envelope protein. Here we report that in addition to reducing viral infectivity, M2BP inhibits HIV-1 virion production. We provide evidence showing that M2BP inhibits HIV-1 Gag trafficking to the plasma membrane in a vimentin-dependent manner. When vimentin filaments were collapsed by treating cells with acrylamide or by overexpression of a dominant-negative mutant of vimentin, M2BP inhibition of HIV-1 virion production was significantly relieved. We further show that M2BP interacts with both HIV-1 Gag and vimentin and thereby mediates their interactions. We propose that M2BP traps HIV-1 Gag to vimentin filaments to inhibit the transportation of HIV-1 Gag to the plasma membrane. These findings uncover a novel mechanism by which a host antiviral factor inhibits HIV-1 virion production.
Circulating plant miRNAs can regulate human gene expression in vitro
Authors: Pastrello Chiara , Tsay Mike , McQuaid Rosanne , Abovsky Mark , Pasini Elisa , Shirdel Elize , Angeli Marc , Tokar Tomas , Jamnik Joseph , Kotlyar Max , Jurisicova Andrea , Kotsopoulos Joanne , El-Sohemy Ahmed , Jurisica Igor
Published: September 2016

While Brassica oleracea vegetables have been linked to cancer prevention, the exact mechanism remains unknown. Regulation of gene expression by cross-species microRNAs has been previously reported; however, its link to cancer suppression remains unexplored. In this study we address both issues. We confirm plant microRNAs in human blood in a large nutrigenomics study cohort and in a randomized dose-controlled trial, finding a significant positive correlation between the daily amount of broccoli consumed and the amount of microRNA in the blood. We also demonstrate that Brassica microRNAs regulate expression of human genes and proteins in vitro, and that microRNAs cooperate with other Brassica-specific compounds in a possible cancer-preventive mechanism. Combined, we provide strong evidence and a possible multimodal mechanism for broccoli in cancer prevention.
Chemical exposure-response relationship between air pollutants and reactive oxygen species in the human respiratory tract
Authors: Lakey Pascale S. J. , Berkemeier Thomas , Tong Haijie , Arangio Andrea M. , Lucas Kurt , Pöschl Ulrich , Shiraiwa Manabu
Published: September 2016

Air pollution can cause oxidative stress and adverse health effects such as asthma and other respiratory diseases, but the underlying chemical processes are not well characterized. Here we present chemical exposure-response relations between ambient concentrations of air pollutants and the production rates and concentrations of reactive oxygen species (ROS) in the epithelial lining fluid (ELF) of the human respiratory tract. In highly polluted environments, fine particulate matter (PM2.5) containing redox-active transition metals, quinones, and secondary organic aerosols can increase ROS concentrations in the ELF to levels characteristic for respiratory diseases. Ambient ozone readily saturates the ELF and can enhance oxidative stress by depleting antioxidants and surfactants. Chemical exposure-response relations provide a quantitative basis for assessing the relative importance of specific air pollutants in different regions of the world, showing that aerosol-induced epithelial ROS levels in polluted megacity air can be several orders of magnitude higher than in pristine rainforest air.
miR-502 medaited histone methyltransferase SET8 expression is associated with outcome of esophageal squamous cell carcinoma
Authors: Wang Cuiju , Wu Jianhua , Zhao Yue , Guo Zhanjun
Published: September 2016

The histone methyltransferase SET8, whose expression is regulated by miR-502 though the binding site in the 3′ UTR of SET8, implicated in cancer development. Single nucleotide polymorphism (SNP) of rs16917496 located in the miR-502 and SET8 binding site was analyzed in esophageal squamous cell carcinoma (ESCC) patients, the SET8 C/C genotype was independently associated with longer post-operative survival by multivariate analysis (relative risk, 2.250; 95% CI, 1.041–4.857; p = 0.039). Moreover, the reduced SET8 expression mediated by SET8 C/C genotype was associated with longer ESCC survival. Functional assay indicated that the SET8 knock down could inhibit proliferation and promote apoptosis of ESCC cells. The subsequent assay also showed the markedly inhibition of ESCC cell migration and invasion by SET8 knock down. Our data suggested that the altering SET8 expression, which is mediated at least partly by miR-502 through changing the binding affinity between miR-502 and SET8 3′ UTR, could modify the ESCC outcome by inhibiting the proliferation and invasion as well as promoting the apoptosis of ECSS cell. Our data indicated that SET8 was a new target for ESCC therapy.
Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding
Authors: Panico Maria , Bouché Laura , Binet Daniel , O’Connor Michael-John , Rahman Dinah , Pang Poh-Choo , Canis Kevin , North Simon J. , Desrosiers Ronald C. , Chertova Elena , Keele Brandon F. , Bess Julian W. , Lifson Jeffrey D. , Haslam Stuart M. , Dell Anne , Morris Howard R.
Published: September 2016

The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120SU plays an essential role in virus binding to target CD4+ T-cells and is a major vaccine target. Gp120 has remarkably high levels of N-linked glycosylation and there is considerable evidence that this “glycan shield” can help protect the virus from antibody-mediated neutralization. In recent years, however, it has become clear that gp120 glycosylation can also be included in the targets of recognition by some of the most potent broadly neutralizing antibodies. Knowing the site-specific glycosylation of gp120 can facilitate the rational design of glycopeptide antigens for HIV vaccine development. While most prior studies have focused on glycan analysis of recombinant forms of gp120, here we report the first systematic glycosylation site analysis of gp120 derived from virions produced by infected T lymphoid cells and show that a single site is exclusively substituted with complex glycans. These results should help guide the design of vaccine immunogens.
Effect of land use and hydrological processes on Escherichia coli concentrations in streams of tropical, humid headwater catchments
Authors: Rochelle-Newall Emma J. , Ribolzi Olivier , Viguier Marion , Thammahacksa Chanthamousone , Silvera Norbert , Latsachack Keooudone , Dinh Rinh Pham , Naporn Piyapong , Sy Hai Tran , Soulileuth Bounsamay , Hmaimum Nikom , Sisouvanh Pem , Robain Henri , Janeau Jean-Louis , Valentin Christian , Boithias Laurie , Pierret Alain
Published: September 2016

Lack of access to clean water and adequate sanitation continues to be a major brake on development. Here we present the results of a 12-month investigation into the dynamics of Escherichia coli, a commonly used indicator of faecal contamination in water supplies, in three small, rural catchments in Laos, Thailand and Vietnam. We show that land use and hydrology are major controlling factors of E. coli concentrations in streamwater and that the relative importance of these two factors varies between the dry and wet seasons. In all three catchments, the highest concentrations were observed during the wet season when storm events and overland flow were highest. However, smaller peaks of E. coli concentration were also observed during the dry season. These latter correspond to periods of intense farming activities and small, episodic rain events. Furthermore, vegetation type, through land use and soil surface crusting, combined with mammalian presence play an important role in determining E. coli loads in the streams. Finally, sampling during stormflow revealed the importance of having appropriate sampling protocols if information on maximum contamination levels is required as grab sampling at a fixed time step may miss important peaks in E. coli numbers.
Strong coupling of Asian Monsoon and Antarctic climates on sub-orbital timescales
Authors: Chen Shitao , Wang Yongjin , Cheng Hai , Edwards R. Lawrence , Wang Xianfeng , Kong Xinggong , Liu Dianbing
Published: September 2016

There is increasing evidence that millennial-scale climate variability played an active role on orbital-scale climate changes, but the mechanism for this remains unclear. A 230Th-dated stalagmite δ18O record between 88 and 22 thousand years (ka) ago from Yongxing Cave in central China characterizes changes in Asian monsoon (AM) strength. After removing the 65°N insolation signal from our record, the δ18O residue is strongly anti-phased with Antarctic temperature variability on sub-orbital timescales during the Marine Isotope Stage (MIS) 3. Furthermore, once the ice volume signal from Antarctic ice core records were removed and extrapolated back to the last two glacial-interglacial cycles, we observe a linear relationship for both short- and long-duration events between Asian and Antarctic climate changes. This provides the robust evidence of a link between northern and southern hemisphere climates that operates through changes in atmospheric circulation. We find that the weakest monsoon closely associated with the warmest Antarctic event always occurred during the Terminations. This finding, along with similar shifts in the opal flux record, suggests that millennial-scale events play a key role in driving the deglaciation through positive feedbacks associated with enhanced upwelling and increasing CO2.
CollagenVI-Cre mice: A new tool to target stromal cells in secondary lymphoid organs
Authors: Prados Alejandro , Kollias George , Koliaraki Vasiliki
Published: September 2016

Stromal cells in secondary lymphoid organs (SLOs) are non-hematopoietic cells involved in the regulation of adaptive immune responses. Three major stromal populations have been identified in adult SLOs: fibroblastic reticular cells (FRCs), follicular dendritic cells (FDCs) and marginal reticular cells (MRCs). The properties of these individual populations are not clearly defined, mainly due to the lack of appropriate genetic tools, especially for MRCs. Here, we analyzed stromal cell targeting in SLOs from a transgenic mouse strain that expresses Cre recombinase under the CollagenVI promoter, using lineage tracing approaches. We show that these mice target specifically MRCs and FDCs, but not FRCs in Peyer’s patches and isolated lymphoid follicles in the intestine. In contrast, stromal cells in lymph nodes and the spleen do not express the transgene, which renders ColVI-cre mice ideal for the specific targeting of stromal cells in the gut-associated lymphoid tissue (GALT). This funding further supports the hypothesis of organ-specific stromal precursors in SLOs. Interestingly, in all tissues analyzed, there was also high specificity for perivascular cells, which have been proposed to act as FDC precursors. Taken together, ColVI-Cre mice are a useful new tool for the dissection of MRC- and FDC-specific functions and plasticity in the GALT.
Important Variation in Vibrational Properties of LiFePO4 and FePO4 Induced by Magnetism
Authors: Seifitokaldani Ali , Gheribi Aïmen E. , Phan Anh Thu , Chartrand Patrice , Dollé Mickaël
Published: September 2016

A new thermodynamically self-consistent (TSC) method, based on the quasi-harmonic approximation (QHA), is used to obtain the Debye temperatures of LiFePO4 (LFP) and FePO4 (FP) from available experimental specific heat capacities for a wide temperature range. The calculated Debye temperatures show an interesting critical and peculiar behavior so that a steep increase in the Debye temperatures is observed by increasing the temperature. This critical behavior is fitted by the critical function and the adjusted critical temperatures are very close to the magnetic phase transition temperatures in LFP and FP. Hence, the critical behavior of the Debye temperatures is correlated with the magnetic phase transitions in these compounds. Our first-principle calculations support our conjecture that the change in electronic structures, i.e. electron density of state and electron localization function, and consequently the change in thermophysical properties due to the magnetic transition may be the reason for the observation of this peculiar behavior of the Debye temperatures.
Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin
Authors: Mansuroglu Zeyni , Benhelli-Mokrani Houda , Marcato Vasco , Sultan Audrey , Violet Marie , Chauderlier Alban , Delattre Lucie , Loyens Anne , Talahari Smail , Bégard Séverine , Nesslany Fabrice , Colin Morvane , Souès Sylvie , Lefebvre Bruno , Buée Luc , Galas Marie-Christine , Bonnefoy Eliette
Published: September 2016

Pericentromeric heterochromatin (PCH) gives rise to highly dense chromatin sub-structures rich in the epigenetic mark corresponding to the trimethylated form of lysine 9 of histone H3 (H3K9me3) and in heterochromatin protein 1α (HP1α), which regulate genome expression and stability. We demonstrate that Tau, a protein involved in a number of neurodegenerative diseases including Alzheimer’s disease (AD), binds to and localizes within or next to neuronal PCH in primary neuronal cultures from wild-type mice. Concomitantly, we show that the clustered distribution of H3K9me3 and HP1α, two hallmarks of PCH, is disrupted in neurons from Tau-deficient mice (KOTau). Such altered distribution of H3K9me3 that could be rescued by overexpressing nuclear Tau protein was also observed in neurons from AD brains. Moreover, the expression of PCH non-coding RNAs, involved in PCH organization, was disrupted in KOTau neurons that displayed an abnormal accumulation of stress-induced PCH DNA breaks. Altogether, our results demonstrate a new physiological function of Tau in directly regulating neuronal PCH integrity that appears disrupted in AD neurons.
Infrared spectroscopy via substrate-integrated hollow waveguides: a powerful tool in catalysis research
Authors: Kokoric V. , Widmann D. , Wittmann M. , Behm R. J. , Mizaikoff B.
Published: September 2016

Monitoring catalyst performance via substrate-integrated hollow waveguide (iHWGs) assisted infrared spectroscopy.
Monitoring metabolite change in ice stored ghol fish (Protonibea diacanthus) by using a1H NMR technique: identification of pyruvate as a spoilage marker
Authors: Nair Ratish R. , Joshi Nidhi , Boricha Vinod P. , Haldar Soumya , Chatterjee Pabitra B.
Published: September 2016

1H NMR spectroscopy based metabolic analysis of ice storedProtonibea diacanthustissue extracts points to the prospect of pyruvate becoming a probable marker for their quality assessment.
An aptasensor based on cobalt oxyhydroxide nanosheets for the detection of thrombin
Authors: Yang Yuan , Cen Yao , Deng Wen-Jing , Yu Ru-Qin , Chen Ting-Ting , Chu Xia
Published: September 2016

An aptasensor based on a fluorophore-labelled aptamer and cobalt oxyhydroxide (CoOOH) nanosheets was developed for determining the concentration of thrombin.
Gold nanoclusters-catalyzed rhodamine 6G–K3Fe(CN)6chemiluminescence and its application
Authors: Yang Dongqin , He Yanyan , Sui Yanyan , Chen Funan
Published: September 2016

An ultra-facile flow injection chemiluminescence (CL) strategy was designed for bisphenol A (BPA) detection.
Synthesis and deposition of a Tröger’s base polymer on the electrode surface for potentiometric detection of a neuroblastoma tumor marker metabolite
Authors: Shishkanova T. V. , Havlík M. , Dendisová M. , Matějka P. , Král V.
Published: September 2016

We propose an innovative approach to detect a low molecular weight metabolite of neuroblastoma.
Crystals on the move: mechanical effects in dynamic solids
Authors: Commins Patrick , Desta Israel Tilahun , Karothu Durga Prasad , Panda Manas K. , Naumov Panče
Published: September 2016

When exposed to external stimuli such as heat or light, certain single crystals can acquire momentum and undergo motion.
Mechanistic insights into lithium ion battery electrolyte degradation – a quantitative NMR study
Authors: Wiemers-Meyer S. , Winter M. , Nowak S.
Published: September 2016

Water as the main driving force of LiPF6 degradation increases the reaction rate and determines the composition of degradation products.
Hydrogen bonding and delocalization in the ELF analysis approach
Authors: Silvi Bernard , Ratajczak Henryk
Published: September 2016

Delocalization in hydrogen bonded systems is revealed by ELF along the interaction line.
Tri-, tetra-, and hexanuclear mixed-valence molybdenum clusters: structural diversity and catalysis of acetylene hydrogenation
Authors: Kuznetsov Denis A. , Bazhenova Tamara A. , Fedyanin Ivan V. , Martynenko Vyacheslav M. , Shestakov Alexander F. , Petrova Galina N. , Komarova Natal'ya S.
Published: September 2016

A series of novel polynuclear molybdenum alkoxides was synthesized and explored in catalytic acetylene hydrogenation.
A rational design of separator with substantially enhanced thermal features for lithium-ion batteries by the polydopamine–ceramic composite modification of polyolefin membranes
Authors: Dai Jianhui , Shi Chuan , Li Chao , Shen Xiu , Peng Longqing , Wu Dezhi , Sun Daoheng , Zhang Peng , Zhao Jinbao
Published: September 2016

We report a rational design of separator for lithium-ion batteries by the polydopamine–ceramic composite-modification of polyolefin membranes, which leads to substantially enhanced thermal and mechanical stability.
A monolithic metal-free electrocatalyst for oxygen evolution reaction and overall water splitting
Authors: Balogun Muhammad-Sadeeq , Qiu Weitao , Yang Hao , Fan Wenjie , Huang Yongchao , Fang Pingping , Li Gaoren , Ji Hongbing , Tong Yexiang
Published: September 2016

Herein, a three-dimensional monolithic and metal-free N-doped porous carbon cloth electrocatalyst was fabricated.
Engineering affinity agents for the detection of hemi-methylated CpG sites in DNA
Authors: Tam B. E. , Sung K. , Sikes H. D.
Published: September 2016

A methyl-binding domain protein was engineered to bind to hemi-methylated DNA and tested in a biochip-based methylation detection assay.
Application of Ni/Co-based metal–organic frameworks (MOFs) as an advanced electrode material for supercapacitors
Authors: Gholipour-Ranjbar Habib , Soleimani Mohammad , Naderi Hamid Reza
Published: September 2016

A Ni/Co–MOF-based supercapacitor electrode exhibited high specific capacitance, and good rate and cycling performance.
Tin powder-promoted one-pot synthesis of 3-spiro-fused or 3,3′-disubstituted 2-oxindoles
Authors: Wang Juanjuan , Huang Danfeng , Wang Ke-Hu , Peng Xiansha , Su Yingpeng , Hu Yulai , Fu Ying
Published: September 2016

A convenient and efficient method for the constructions of 3-spirooxindole derivatives or 3,3′-disubstituted oxindoles has been developed from one-pot reactions of isatins, hydrazides or aromatic amines, 2-(bromomethyl)acrylic ester in the presence of a catalytic amount of Brønsted or Lewis acid promoted by tin powder instead of toxic stannanes.
The effect of photocatalyst excited state lifetime on the rate of photoredox catalysis
Authors: Ochola J. R. , Wolf M. O.
Published: September 2016

Four different iridium(iii) polypyridyl complexes with varying excited state lifetimes are used as photocatalysts to study the effect of excited state lifetime on the rate of a prototypical photoredox-catalyzed reaction, the trifluoromethylation of quinoline.
On-surface synthesis approach to preparing one-dimensional organometallic and poly-p-phenylene chains
Authors: Zhou Xiong , Bebensee Fabian , Shen Qian , Bebensee Regine , Cheng Fang , He Yang , Su Hui , Chen Wei , Xu Guo Qin , Besenbacher Flemming , Linderoth Trolle R. , Wu Kai
Published: September 2016

Substrates and extrinsic metals on top dictate the reaction intermediates and pathways of on-surface Ullmann couplings.
Ultrafast piezo-photocatalytic degradation of organic pollutions by Ag2O/tetrapod-ZnO nanostructures under ultrasonic/UV exposure
Authors: Sun Cong , Fu Yongming , Wang Qiang , Xing Lili , Liu Baodan , Xue Xinyu
Published: September 2016

Ultrafast degradation of organic pollutions has been realized by the piezo-photocatalytic activity of Ag2O/tetrapod-ZnO nanostructures under ultrasonic/UV irradiation.
Fabrication of well-ordered silicon nanopillars embedded in a microchannel via metal-assisted chemical etching: a route towards an opto-mechanical biosensor
Authors: Solis-Tinoco V. , Marquez S. , Sepulveda B. , Lechuga L. M.
Published: September 2016

Nanofabrication methodology that integrates the creation of silicon nanopillars inside a microfluidic channel which has significant implications for the achievement of new optomechanical biosensors.
Potential prospects for carbon dots as a fluorescence sensing probe for metal ions
Authors: Chaudhary Savita , Kumar Sandeep , Kaur Bhawandeep , Mehta S. K.
Published: September 2016

The well defined emission properties of CQDs have encouraged further investigation of their prospects in chemo-sensing applications for the identification of Cr3+ ions in aqueous media.
Monitoring quality consistency of Ixeris sonchifolia (Bunge) Hance injection by integrating UV spectroscopic fingerprints, a multi-wavelength fusion fingerprint method, antioxidant activities and UHPLC/Q-TOF-MS
Authors: Yang Lanping , Xie Xiuman , Yang Liu , Zhang Jing , Sun Guoxiang
Published: September 2016

Traditional Chinese medicines/herbal medicines (TCM/HM) are too complicated mixture systems to investigate their quality consistency effectively using a single detection technique.
Methylamine acts as excellent chemical trigger to Harden emulsion droplets into spongy PLGA microspheres
Authors: Kim Yuyoung , Kim Hansol , Sah Hongkee
Published: September 2016

A unique approach using methylamine as a chemical trigger leads to the formation of sponge-like PLGA microspheres with extreme porosity.
Exploring the stability and electronic structure of beryllium and sulphur co-doped graphene: a first principles study
Authors: Olaniyan O. , Mapasha R. E. , Momodu D. Y. , Madito M. J. , Kahleed A. A. , Ugbo F. U. , Bello A. , Barzegar F. , Oyedotun K. , Manyala N.
Published: September 2016

First principles density functional theory calculations have been performed to explore the stability, structural and electronic properties of Be and S co-doped graphene sheets.
Homocoupling of heteroaryl/aryl/alkyl Grignard reagents: I2-promoted, or Ni- or Pd- or Cu- or nano-Fe-based salt catalyzed
Authors: Li Xing , Li Dongjun , Li Yingjun , Chang Honghong , Gao Wenchao , Wei Wenlong
Published: September 2016

Five efficient processes for the homo-coupling of various Grignard reagents including aryl, heteroaryl and aliphatic ones in the presence of I2, Pd(OAc)2, Ni(OAc)2, CuI, and nano-Fe3O4 were developed, respectively.
First-principles insight into the photoelectronic properties of Ge-based perovskites
Authors: Lu Xiaoqing , Zhao Zigang , Li Ke , Han Zhaoxiang , Wei Shuxian , Guo Chen , Zhou Sainan , Wu Zhonghua , Guo Wenyue , Wu Chi-man Lawrence
Published: September 2016

First-principles investigations were performed to elucidate the effects of A and X in Ge-based MAGeX3perovskites (MA = CH3NH3+; X = Cl−, Br−, and I−) and AGeI3(A = Cs+, CH3NH3+, HC(NH2)2+, CH3C(NH2)2+, and C(NH2)3+) on the photoelectronic properties.
In situ polymerization of a novel surfactant on a graphene surface for the stable dispersion of graphene in water
Authors: Higashi Chisato , Funasaki Yuichi , Iguchi Hiroki , Maruyama Tatsuo
Published: September 2016

A graphene surface is functionalized with a polymerizable surfactant by in situ polymerization for the stable colloidal dispersion of graphene.
Structural investigation of nickel polyphosphate coacervate glass–ceramics
Authors: Franco Douglas F. , Manzani Danilo , Barud Hernane S. , Antonio Selma G. , de Oliveira Luiz F. C. , Silva Maurício A. P. , Ribeiro Sidney J. L. , Nalin Marcelo
Published: September 2016

Nickel polyphosphate coacervates have been prepared through the coacervation process of sodium polyphosphate and Ni2+ chloride solutions.
Carbon dots–quinoline derivative nanocomposite: facile synthesis and application as a “turn-off” fluorescent chemosensor for detection of Cu2+ ions in tap water
Authors: Li Qian , Huang Qitong , Zhu Jie-Ji , Ji Wen-Gang , Tong Qing-Xiao
Published: September 2016

In this paper, a novel quinoline derivative: 8-(pyridin-2-ylmethoxy)quinoline-2-carboxylic acid (Q) has been successfully synthesized, then it was coupled with carbon dots (CDs) to synthesize a CDs–Q nanocomposite by a simple and green method.
Supramolecular peptide amphiphile based nanocarrier for pH-triggered Dox release, overcoming drug resistance
Authors: Lu Sheng , Ding Yong , Cui Weijia , Pan Ran , Xu Wen , Chen P.
Published: September 2016

Self-assembled peptide amphiphile–doxorubicin conjugates showed pH-triggered drug release and ability to combat the drug resistance in cancer cells.
Effect of pore size and shape on the thermal conductivity of metal-organic frameworks
Authors: Babaei Hasan , McGaughey Alan J. H. , Wilmer Christopher E.
Published: September 2016

We investigate the effect of pore size and shape on the thermal conductivity of a series of idealized metal-organic frameworks (MOFs) containing adsorbed gas using molecular simulations.
Dynamic scaling of ferromagnetic micro-rod clusters under a weak magnetic field
Authors: Cheng Rui , Zhu Lu , Huang Weijie , Mao Leidong , Zhao Yiping
Published: September 2016

Ferromagnetic microrod clusters (FMRCs) rearrange from a side-by-side raft-like structure to an end-to-end chain-like structure, originating from coupled motions through the field-driven alignment of both ferromagnetic microrods and FMRCs.
Phosphonium salt and ZnX2–PPh3integrated hierarchical POPs: tailorable synthesis and highly efficient cooperative catalysis in CO2utilization
Authors: Li Cunyao , Wang Wenlong , Yan Li , Wang Yuqing , Jiang Miao , Ding Yunjie
Published: September 2016

Phosphonium salt and ZnX2–PPh3integrated POPs have been successful synthesized and were employed in cooperative catalytic preparation of cyclic carbonates.
Bifunctional CoP and CoN porous nanocatalysts derived from ZIF-67 in situ grown on nanowire photoelectrodes for efficient photoelectrochemical water splitting and CO2 reduction
Authors: Weng Baicheng , Wei Wei , Yiliguma Yiliguma , Wu Hao , Alenizi Abdullah M. , Zheng Gengfeng
Published: September 2016

The in situ fabricated photoelectrodes derived from ZIF-67 exhibited greatly enhanced photoelectrochemical performances for full water splitting and CO2 reduction.
Deep blue-emissive bifunctional (hole-transporting + emissive) materials with CIEy∼ 0.06 based on a ‘U’-shaped phenanthrene scaffold for application in organic light-emitting diodes
Authors: Jhulki Samik , Mishra Abhaya Kumar , Ghosh Avijit , Chow Tahsin J. , Moorthy Jarugu Narasimha
Published: September 2016

Phenanthrenes functionalized two-fold at 3,6 positions by fluorophoric amines,i.e.,PTPA,PDPAandPCZL, serve as very good bifunctional materials (HTM + EM) with deep blue emission in simple double layer OLED devices.
Nitrogen-doped multilayered nanographene derived from Ni3C with efficient electron field emission
Authors: Wu Dajun , Zhang Chi , Xu Shaohui , Zhu Yiping , Xiong Dayuan , Guo Pingsheng , Wu Yishan , Qi Ruijuan , Huang Rong , Wang Lianwei , Chu Paul K.
Published: September 2016

Field emitters based on N-doped multilayered nanographene derived from Ni3C films are demonstrated to have strong adhesion to the substrate, and indicating a excellent field emission characteristic.
Closed‐form smoothers and shapers with distributed delay for damped oscillatory modes
Authors: Alikoç Baran , Vyhlídal Tomáš , Ergenç Ali Fuat
Published: September 2016

The study deals with parametrisation of input shapers and smoothers with distributed delays, which are a common tool used for pre‐compensating oscillatory modes of flexible systems. These filtering structures can be easily parametrised, if the oscillatory mode is undamped, leading to fully analytical formulas. For the damped case, however, the parametrisation needs to be done numerically as a rule. Utilising a straightforward complex domain transformation, as the main results, the structure of the filters is turned to the closed‐form that can be parametrised analytically for the damped case too. The adjusted smoothers and shapers accommodate the reference and the system output signals without vibration at the same time lengths like the pre‐forms for the undamped case. This methodology is applied to Trapezoidal, S ‐curve and Trigonometric smoothers, Jerk Limited shaper and recently proposed Zero Vibration shaper with a distributed delay. The proposed new types of smoothers and shapers, which are essentially based on exponential distribution of delays, are investigated in time and frequency domains. Subsequently, the basic properties, i.e. response performances, spectrum distribution and robustness analysis, are demonstrated and cross‐compared in a case study example.
Design approach of discrete‐time resonant controllers for uninterruptible power supply applications through frequency response analysis
Authors: Carballo Roberto Esteban , Botterón Fernando , Oggier Germán Gustavo , García Guillermo Oscar
Published: September 2016

A new methodology to design discrete‐time multiple resonant controllers for single‐phase uninterruptible power supply inverters is proposed in this study. This methodology is based on classical linear tools and consists on the synthesis of the inverter output impedance according to standard specifications. This synthesis is performed using a multi‐loop control strategy composed of an inner current control loop using a proportional controller, and an outer voltage control loop using the multiple resonant controller. A prototype was built to demonstrate the practical feasibility of the theoretical proposal. A significant reduction of the output impedance at determined harmonic frequencies resulted in a low‐voltage total harmonic distortion of the output voltage of about 1.76%, for IEC 62040‐3 reference non‐linear load.
BuFaTa 2016 auf dem Klinikkongress Ruhr: Sensor statt Strippe
Authors: Kohrs Jens
Published: September 2016

Digitalisierung ist das Wort der Stunde. Auch die Krankenhaustechnik wird zunehmend vernetzt, und die Technikabteilungen müssen eingespielte Abläufe infrage stellen. Doch wo ist Digitalisierung wirklich sinnvoll? Und wie macht sie Krankenhäuser effizienter?
Fatal Liver and Lung Alveolar Echinococcosis with Newly Developed Neurologic Symptoms due to the Brain Involvement
Authors: Kvascevicius Robertas , Lapteva Ona , Awar Omar , Audronyte Egle , Neverauskiene Laura , Kvasceviciene Eleonora , Sokolovas Vitalijus , Strupas Kestutis , Marcinkute Audrone , Deplazes Peter , Müllhaupt Beat
Published: September 2016

The fox tapeworm Echinococcus multilocularis causes human alveolar echinococcosis, commonly affecting the liver. However, in ∼1% of cases, systematic spread of the disease involves the brain as well. A patient had a 6-year history of liver and lung alveolar echinococcosis that was considered not suitable for surgery, and treatment with albendazole was introduced. After the appearance of neurologic disturbances, an intracranial mass lesion was demonstrated by radiologic imaging. The lesion was surgically removed, and histologic analysis revealed metacestode tissue of E. multilocularis. Despite the surgical resection of the lesion, the patient died of progression of systemic alveolar echinococcosis. The authors highly recommend implementing neurologic monitoring to the follow-up algorithm for patients with systemically disseminated alveolar echinococcosis. When neurologic symptoms occur, radiologic imaging of the brain should be obtained immediately. Surgery should be considered for all intracranial echinococcal lesions, unless the lesion is located in the eloquent brain area.
Surgical Management of Hiatal Hernia in Children with Asplenia Syndrome
Authors: Fukumoto Koji , Yamoto Masaya , Nouso Hiroshi , Kaneshiro Masakatsu , Koyama Mariko , Urushihara Naoto , Miyake Hiromu
Published: September 2016

Purpose Patients with asplenia syndrome (AS) are likely to have upper gastrointestinal tract malformations such as hiatal hernia. This report discusses the treatment of such conditions.

Methods Seventy-five patients with AS underwent initial palliation in our institution between 1997 and 2013. Of these, 10 patients had hiatal hernia. Of the patients with hiatal hernia, 6 had brachyesophagus and 7 had microgastria.

Results Of the 10 patients with hiatal hernia, 9 underwent surgery in infancy (7 before Glenn operation, 2 after Glenn operation). Two underwent typical Toupet fundoplication, and the other 7 underwent atypical repair including reduction of the stomach. Two patients with atypical repair showed recurrence of hernia and required reoperation. Three patients required reoperation due to duodenal obstruction. Duodenal obstruction occurred due to preduodenal portal vein or abnormal vessels compressing the duodenum. Obstructive symptoms were not seen in any cases preoperatively.

Conclusions In patients with hiatal hernia, typical fundoplication is often difficult because most have concomitant brachyesophagus, microgastria, and hypoplasia of the esophageal hiatus. However, we should at least reduce the stomach to the abdominal cavity as early as possible to increase thoracic cavity volume and allow good feeding. Increasing the volume of the thoracic cavity thus makes Glenn and Fontan circulations more stable. Duodenal obstruction secondary to vascular anomalies is also common, so the anatomy in the area near the duodenum should be evaluated pre- and intraoperatively.
Airy acoustical–sheet spinner tweezers
Authors: Mitri F. G.
Published: September 2016

The Airy acoustical beam exhibits parabolic propagation and spatial acceleration, meaning that the propagation bending angle continuously increases before the beam trajectory reaches a critical angle where it decays after a propagation distance, without applying any external bending force. As such, it is of particular importance to investigate its properties from the standpoint of acoustical radiation force, spin torque, and particle dynamics theories, in the development of novel particle sorting techniques and acoustically mediated clearing systems. This work investigates these effects on a two-dimensional (2D) circular absorptive structure placed in the field of a nonparaxial Airy “acoustical-sheet” (i.e., finite beam in 2D), for potential applications in surface acoustic waves and acousto-fluidics. Based on the characteristics of the acoustic field, the beam is capable of manipulating the circular cylindrical fluid cross-section and guides it along a transverse or parabolic trajectory. This feature of Airy acoustical beams could lead to a unique characteristic in single-beam acoustical tweezers related to acoustical sieving, filtering, and removal of particles and cells from a section of a small channel. The analysis developed here is based on the description of the nonparaxial Airy beam using the angular spectrum decomposition of plane waves in close association with the partial-wave series expansion method in cylindrical coordinates. The numerical results demonstrate the ability of the nonparaxial Airy acoustical-sheet beam to pull, propel, or accelerate a particle along a parabolic trajectory, in addition to particle confinement in the transverse direction of wave propagation. Negative or positive radiation force and spin torque causing rotation in the clockwise or the anticlockwise direction can occur depending on the nondimensional parameter ka (where k is the wavenumber and a is the radius) and the location of the cylinder in the beam. Applications in acoustic levitation, long-distance particle transport and manipulation, as well as acousto-fluidics directly benefit from the results of this analysis.
Stochastic analysis of wind energy uncertainty impact on ISO risk-taking in joint energy and reserve markets using conditional value at risk
Authors: Saboori Saeid , Kazemzadeh Rasool , Saboori Hedayat
Published: September 2016

Uncertainty management of the large scale wind power resources is mainly known as one of the most challenging aspects in future electricity market operations, where network operation may put at risk due to the wind power forecasting errors. Therefore, it is necessary to evaluate the impact of the wind power uncertainty on the operator risk-taking by using validated tools. This paper proposes a new mixed integer linear programming model for joint energy and reserve market clearing taking into account the co-optimization of the market clearing and operation cost of the thermal units. Also, wind power uncertainty is handled by means of two-stage stochastic programming and risk concept is introduced and formulated via a well-known measure to account for operator risk taking level. The proposed model is formulated as a two-stage stochastic programming where it clears the joint energy and reserve markets considering different penetration and forecasting accuracy levels of the wind power. Furthermore, supplementary terms are added to the objective function and constraints of the problem in order to measure the risk related to the wind power uncertainty.
Controllable preparation of copper phthalocyanine single crystal nano column and its chlorine gas sensing properties
Authors: Zhao Jianhong , Qiao Zhenfang , Zhang Yumin , Zou Taoyu , Yu Leiming , Luo Li , Wang Xiaoyan , Yang Yiji , Wang Hai , Tang Libin
Published: September 2016

The unsubstituted copper phthalocyanine (CuPc) single crystal nano columns were fabricated for the first time as chlorine (Cl2) gas sensors in this paper. The nano columns of CuPc have been prepared on different substrates via template-free physical vapor deposition (PVD) approach. The growth mechanism of CuPc nano column on quartz was explored and the same condition used on other substrates including glass, sapphire (C-plane<0001>, M-plane<101¯0>, R-plane<11¯02>), Si and SiO2/Si came to a same conclusion, which confirmed that the aligned growth of CuPc nano column is not substrate-dependent. And then the CuPc nano column with special morphology was integrated as in-situ sensor device which exhibits high sensitivity and selectivity towards Cl2 at room temperature with a minimum detection limit as low as 0.08 ppm. The response of sensor was found to increase linearly (26∼659%) with the increase for Cl2 within concentration range (0.08∼4.0ppm). These results clearly demonstrate the great potential of the nano column growth and device integration approach for sensor device.
Induced conductivity in sol-gel ZnO films by passivation or elimination of Zn vacancies
Authors: Winarski D. J. , Anwand W. , Wagner A. , Saadatkia P. , Selim F. A. , Allen M. , Wenner B. , Leedy K. , Allen J. , Tetlak S. , Look D. C.
Published: September 2016

Undoped and Ga- and Al- doped ZnO films were synthesized using sol-gel and spin coating methods and characterized by X-ray diffraction, high-resolution scanning electron microscopy (SEM), optical spectroscopy and Hall-effect measurements. SEM measurements reveal an average grain size of 20 nm and distinct individual layer structure. Measurable conductivity was not detected in the unprocessed films; however, annealing in hydrogen or zinc environment induced significant conductivity (∼10−2 Ω.cm) in most films. Positron annihilation spectroscopy measurements provided strong evidence that the significant enhancement in conductivity was due to hydrogen passivation of Zn vacancy related defects or elimination of Zn vacancies by Zn interstitials which suppress their role as deep acceptors. Hydrogen passivation of cation vacancies is shown to play an important role in tuning the electrical conductivity of ZnO, similar to its role in passivation of defects at the Si/SiO2 interface that has been essential for the successful development of complementary metal–oxide–semiconductor (CMOS) devices. By comparison with hydrogen effect on other oxides, we suggest that hydrogen may play a universal role in oxides passivating cation vacancies and modifying their electronic properties.
Thorium silicate compound as a solid-state target for production of isomeric thorium-229 nuclei by electron beam irradiation
Authors: Borisyuk P. V. , Vasilyev O. S. , Lebedinskii Y. Y. , Krasavin A. V. , Tkalya E. V. , Troyan V. I. , Habibulina R. F. , Chubunova E. V. , Yakovlev V. P.
Published: September 2016

In this paper, we discuss an idea of the experiment for excitation of the isomeric transition in thorium-229 nuclei by irradiating with electron beam targets with necessary physical characteristics. The chemical composition and bandgap of ThSi10O22 were determined by X-ray photoelectron spectroscopy and reflection electron energy loss spectroscopy. It was found that the energy gap is equal to 7.7 eV and does not change when the target is exposed to a medium energy electron beam for a long time. This indicates that the compound possesses high electron-beam resistance. A quantitative estimation of the output function of isomeric thorium-229 nuclei generated by interaction of nuclei with the secondary electron flow formed by irradiating the solid-state ThSi10O22-based target is given. The estimation shows that ThSi10O22 is a promising thorium-containing target for investigating excitation of the nuclear low-lying isomeric transition in the thorium-229 isotope using medium-energy electrons.
Extruded full-fat soybean as a substitute for soybean meal and oil in diets for lactating sows: the effect on litter performance and milk composition
Authors: Zhou Pan , Luo Guangbo , Che Lianqiang , Lin Yan , Xu Shengyu , Fang Zhengfeng , Wu De
Published: September 2016

The aim of this study was to determine the effect of supplementing different concentrations of extruded full-fat soybean (EFS) to corn-soybean meal-based lactation diets, at the expense of soybean meal and oil, on sow and litter performance. During gestation, a total of 60 Landrace × Yorkshire multiparous sows were fed the same gestational diet. After farrowing, sows were randomly allotted to one of four treatments including Control (corn-soybean meal-soybean oil), and 6.1%, 12.2%, and 18.3% EFS diets, until Day 21 of lactation. Individual weight at weaning tended to be heavier in the 12.2% EFS group as compared with Controls (P = 0.07). Litter weight in 12.2% EFS group was significantly increased compared with Controls, representing an increase of 7.8%. Average daily feed intake of sows in the 12.2% EFS group tended to increase (P = 0.08) when compared with the other three groups. At Day 21 of lactation, fat and protein content in the milk of the 12.2% EFS group were higher than those of the Control group (P < 0.05). In conclusion, these results demonstrated that feeding lactating sows diets supplemented with EFS had a positive effect on milk composition as well as litter performance. Among the three dietary levels of EFS tested, 12.2% EFS supplementation level showed preferable reproductive performance.
Effect of protein supplementation in the rumen, abomasum, or both on intake, digestibility, and nitrogen utilisation in cattle fed high-quality tropical forage
Authors: Batista E. D. , Detmann E. , Gomes D. I. , Rufino L. M. A. , Paulino M. F. , Valadares Filho S. C. , Franco M. O. , Sampaio C. B. , Reis W. L. S.
Published: September 2016

Effects of differing proportions of ruminal and abomasal protein infusion on intake, digestion, ruminal dynamics and the metabolic parameters of nitrogen (N) compounds were evaluated in beef bulls fed high-quality tropical forage (98.6 g crude protein, CP/kg dry matter) for ad libitum intake. Four Nelore bulls (280 ± 10 kg bodyweight) fitted with ruminal and abomasal cannulas were studied in a 4 × 4 Latin square. Treatments included: Control (no supplement) or 230 g/day of supplemental CP (as casein), with ratios of abomasal : ruminal infusion of 0 : 100, 50 : 50 or 100 : 0. Organic matter intake was not affected by treatments (P ≥ 0.30), though N intake increased by supplementation (P < 0.001). Total CP and organic matter digestibility were increased (P < 0.02) by protein supplementation. Nitrogen balance was 43% greater (P < 0.02) in the treatments with supplementation. Although supplementation did not affect (P = 0.98) the efficiency of absorbed N, a tendency towards a positive linear effect (P = 0.08) was observed when modifying the site of supplementation from the rumen to the abomasum. Supplementation increased (P < 0.01) ruminal ammonia-N, serum urea-N, urinary N and urea-N excretion, which subsequently decreased linearly (P < 0.01) by the displacement of supplementation from the rumen to the abomasum. The results indicate that protein supplementation, either in the rumen or abomasum produces similar effects on N retention. However, the metabolic mechanisms responsible for the improved N retention appear to differ between supplementation sites. Additionally, the efficiency of N utilisation increases with infusion of protein into the abomasum.
Masked Ketenes as Dienophiles in the Diels–Alder Reaction
Authors: Mackay Emily G. , Newton Christopher G.
Published: September 2016

The Diels–Alder reaction is one of the most powerful, well-established, and versatile reactions in organic chemistry; however, its application in certain settings remains a challenge as a result of functional group incompatibility. In this review, we examine the methods in which masked ketenes can be employed as dienophiles, taking particular note of applications in complex settings.