bluuebunny/crossref_metadata_2025 huggingface dataset:
La sucesión en la empresa agraria familiar: el caso valenciano de los arrendamientos rústicos históricos
Authors: Ramón Fernández Francisca
Published: November 2024

El libro que aquí presentamos se corresponde con los trabajos de investigación, en forma de comunicaciones, que fueron presentadas y defendidas por sus autoras/es en el II Congreso internacional «Derecho, Economía, Empresa e Innovación Docente», celebrado en la Universidad Politécnica de Valencia, en su Campus de Alcoy (Alicante), los días 15 y 16 de noviembre de 2024. El éxito de esta iniciativa académica fue patente: 61 comunicaciones aceptadas que entre libro se presentan en forma de capítulos, defendidas/presentadas por un total de 75 autores, de diferentes nacionalidades, provenientes del mundo universitario y/o profesional. Derecho, Economía, Empresa e Innovación Docente gira en torno a seis ejes temáticos, que dan acogida a estos diferentes trabajos de investigación en materia de planificación y organización de la empresa, marketing comercial y comunicación, planificación jurídica internacional de la empresa, e innovación docente y educación. Dentro de cada eje temático los lectores van a encontrar grandes reflexiones sobre «Tecnología, Persona y Derecho», «La importancia del marketing digital en entornos internacionales», «Los efectos del cambio climático y la protección de los derechos humanos de los migrantes», «Transformaciones en el Sector Bancario y sus implicaciones para la inclusión financiera en España», o «La eficacia de los simuladores en las enseñanzas superiores: un estudio comparativo», entre otros; garantizándoles así que el debate científico en el que se convirtió esta segunda edición del Congreso se reproduzca con la lectura de esta obra.
CD8+ T cell subsets in acute infection and anti-tumor immunity
Authors: Shryki Iman
Published: November 2024

CD8+ T cells are key immunotherapeutic targets due to their adaptability and functional diversity. This thesis investigates the utility of the chemokine receptor CX3CR1 in delineating CD8+ T cell functional potentials across various immunological contexts.

In paper I, we introduce the CX3CR1 expression gradient as a predictive tool for assessing the functional potential of memory CD8+ T cells in both human and mouse models. Paper II explores differentiation-unrelated factors influencing CX3CR1 levels in CD8+ T cell cultures. We, therefore, could propose better practices to expand CX3CR1 gradient utility to adoptive cell therapy applications. Paper III examines the phenotypic characteristics of CX3CR1+ CD8+ T cells that arise in response to tumour antigens. I propose that unidentified spatial factors influence anti-tumour CX3CR1+ CD8+ T cell functional potentials and drive intratumoral cells toward dysfunction. Together, these studies contribute to a deeper understanding of CX3CR1 as a biomarker for CD8+ T cell differentiation, offering insights to enhance the clinical outcomes of CD8+ T cell- based therapies.
List of scientific papers
I. Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation. Anthonie Johan Zwijnenburg, Jyoti Pokharel, Renata Varnaitė, Wenning Zheng, Elena Hoffer, IMAN SHRYKI, Natalia Ramirez Comet, Marcus Ehrstrom, Sara Gredmark-Russ, Liv Eidsmo, Carmen Gerlach. Immunity. 2023, 56(8), 1955-1974.e10. https://doi.org/10.1016/j.immuni.2023.06.025

II. The cellular microenvironment regulates CX3CR1 expression on CD8+ T cells and the maintenance of CX3CR1+ CD8+ T cells. Jyoti Pokharel*, IMAN SHRYKI*, Anthonie Johan Zwijnenburg, Ioana Sandu, Laura Krumm, Christina Bekiari, Rebecka Heinbäck, Victor Avramov, Josefin Lysell, Liv Eidsmo, Helena Erlandsson Harris and Carmen Gerlach. European Journal of Immunology. 2024, 54(1):e2350658. https://doi.org/10.1002/eji.202350658

III. CD8+ T cell responses to cytoplasmic antigens in anti-tumor immunity. IMAN SHRYKI, Natalia Ramirez Comet, Carmen Gerlach. [Manuscript]

* Equal contribution
O USO DAS TECNOLOGIAS DE INFORMAÇÃO E COMUNICAÇÃO NO ENVELHECIMENTO HUMANO: REFLEXÃO SOBRE A LIBERDADE SOB A VISÃO PLATÔNICA
Authors: Santos Beatriz Granizo Carvalho
Published: November 2024

The article aims to analyze the effects of communication technology on human aging to ensure freedom, viewed through the lens of the philosopher Plato. By considering Plato's concept of political freedom (freedom in the polis), the article will explore how this freedom can be guaranteed in human aging, with communication technologies being proposed as one possible means. This is especially relevant given that mastering technology has become crucial for individuals to stay informed, establish social relationships, and maintain the freedom to meet their most basic daily needs. It is well known that elderly people face significant difficulties in these areas, which often leads to a restricted sense of freedom in society. Therefore, this article seeks to analyze the use of information technologies as a guarantor of freedom in human aging.
BIOCOSMÉTICOS AMAZÔNICOS: A UTILIZAÇÃO DO AÇAÍ (EUTERPE OLERACEAMART.) EM ESTÉTICA E DERMATOLOGIA
Authors: Stehlgens Jéssica Lima , Silva Weison Lima da , Carvalho Amanda Bezerra
Published: November 2024

Introduction: This study aims to investigate the potential of açaí as an active ingredient in dermatological products, exploring its antioxidant, anti-inflammatory and regenerative properties. General objective: to investigate the potential of açaí as an active ingredient in dermatological biocosmetics and its therapeutic properties for skin health. Methodology: this is a systematic review of the literature following the PRISMA methodology. The research was conducted between August and October 2024, using databases such as PubMed, SciELO and LILACS, with descriptors related to the use of açaí in biocosmetics and dermatology. Results: 147 studies were identified, of which 122 underwent initial screening. After applying the PRISMA criteria, 45 studies were fully evaluated and 12 were selected for detailed analysis. The results of the study show that açaí has a high content of anthocyanins, flavonoids and fatty acids, responsible for its antioxidant, anti-inflammatory and regenerative properties, ideal for dermatological cosmetics. These biomolecules help in the treatment of conditions such as psoriasis, acne and premature aging, in addition to promoting skin hydration and elasticity. Açaí is used in various pharmaceutical forms, such as extracts and creams, demonstrating versatility in the biocosmetics market. Conclusion: Açaí has shown to be a promising ingredient in biocosmetics and dermatology, due to its therapeutic properties. However, the effectiveness of açaí depends on the pharmaceutical form used, suggesting the need for standardization of extracts and more clinical studies to evaluate their applications and benefits in different skin types.
A IMPORTÂNCIA DA ORIENTAÇÃO FARMACÊUTICA QUANTO AO USO IRRACIONAL DO LEVONORGESTREL
Authors: Silva Wanderson Da Silva E , Magalhaes Nayandro Cardoso , Feitosa Wendel Da Silva , Costa Jeyson Cardoso , Carmona Fabio Maués , Carvalho Amanda Bezerra
Published: November 2024

Levonorgestrel, commonly known as the "morning-after pill," is widely used as an emergency contraceptive. However, its improper use can compromise its efficacy and lead to adverse effects, particularly in women with high BMI. The aim of this study is to investigate the impact of incorrect use of levonorgestrel and evaluate the importance of pharmaceutical intervention to ensure its safe and effective use. A systematic review of articles published between 2014 and 2024 was conducted, with searches in the PubMed and Virtual Health Library (VHL) databases. Ten studies on the rational use of levonorgestrel and the role of the pharmacist were analyzed. The results showed that factors such as high body weight reduce the effectiveness of the drug, while incorrect use increases the risk of side effects. Pharmacist intervention proved essential in reducing self-medication cases and improving contraceptive efficacy. Pharmaceutical guidance directly contributes to the safe use of levonorgestrel, minimizing contraceptive failures and adverse effects, and promoting public health.
FATORES ASSOCIADOS À ANSIEDADE, DEPRESSÃO E ESTRESSE EM ESTUDANTES DE MEDICINA EM UMA FACULDADE DO CENTRO SUL BAIANO
Authors: Cardoso Gilson Daniel Lima , Pereira Guilherme Godrim , Moreira Charles Neris
Published: November 2024

O estudo investiga os fatores associados à depressão, ansiedade e estresse em estudantes de medicina, que enfrentam uma carga emocional intensa devido às exigências acadêmicas. Essas condições podem afetar a saúde mental, especialmente em mulheres e alunos nos primeiros períodos do curso, destacando a importância de estratégias institucionais para o bem-estar psicológico. Objetivos: O objetivo principal foi analisar a prevalência e os fatores associados aos sintomas de depressão, ansiedade e estresse entre estudantes de medicina em uma faculdade no centro sul baiano, utilizando a escala DASS-21 e questionários sociodemográficos. Métodos: A pesquisa utilizou um método quantitativo, transversal e descritivo, com uma amostra de 127 estudantes de medicina. Os dados foram coletados por meio de questionários de autopreenchimento online, abordando variáveis ​​como gênero, idade, estado civil, prática de atividade física, qualidade do sono, uso de psicoestimulantes e pressão familiar. Resultados e Discussão: Os resultados indicaram que as mulheres apresentaram maiores níveis de depressão, ansiedade e estresse em comparação aos homens. Estudantes mais jovens, especialmente entre 18 e 22 anos, apresentam níveis elevados de estresse, possivelmente devido à adaptação ao ambiente acadêmico. A prática de atividade física regular e um sono de boa qualidade foram associados a menores índices de sofrimento emocional, enquanto a pressão familiar e o uso de psicoestimulantes aumentaram os sintomas de ansiedade e estresse. Conclusão: Os níveis de depressão, ansiedade e estresse em estudantes de medicina são influenciados por fatores sociodemográficos e hábitos de vida. As instituições de ensino devem implementar programas de apoio psicológico, incentivar a prática de atividades físicas e conscientizar as famílias para reduzir esses sintomas e promover o bem-estar dos futuros médicos.
INVESTIGAÇÃO DOS EFEITOS DOS EXERCÍCIOS PÉLVICOS NA VIDA SEXUAL NO CLIMATÉRIO
Authors: Roque Daniele de Cássia Lúcio , Souza Ingrid Aparecida , Oliveira Ana Paula Bacha de
Published: November 2024

A vida sexual durante o climatério é relevante, uma vez que a sexualidade está presente em todas as fases da vida humana. Conforme as pessoas envelhecem, é fundamental compreender e cuidar da saúde sexual. Estudos apontam melhorias no desempenho sexual em mulheres que foram submetidas a terapia de exercícios pélvicos.  Os exercícios pélvicos são benéficos em mulheres fortalecendo os músculos do assoalho pélvico que desempenham um papel na resposta sexual, uma vez que fortalece os músculos e contribui para a saúde em longo prazo do assoalho pélvico. Metodologia: a amostra foi constituída por 20 participantes, na faixa etária de 60 a 80 anos de idade, com vida sexual ativa,  que concordaram em participar do estudo e atenderam aos critérios de inclusão. A função sexual feminina foi investigada com dois instrumentos: (a) Questionário de avaliação da qualidade de vida sexual feminina (Quociente Sexual – Versão Feminina: QS-F); (b) Questionário FSFI (Female Sexual Function Index). Após a aplicação dos questionários foram realizados exercícios perineais baseados em conscientização e fortalecimento da musculatura do assoalho pélvico (MAP). Em seguida foi aplicado os questionários novamente a fim de verificar o efeito dos exercícios e a evolução da qualidade de vida sexual. Resultados: Pode-se observar o resultado desempenho/satisfação sexual, no qual a maioria das participantes mantém uma vida sexual “regular a boa”. Foi constatado neste estudo que a lubrificação prevaleceu sem diferenças estatísticas, entretanto, os demais itens obtiveram resultados de regular a bom e bom a excelente respectivamente. Conclusão: O processo de mudanças fisiológicas na resposta sexual nesta fase não determinam o fim da vida sexual das idosas. Portanto, é necessária a conscientização dos profissionais de saúde de que mulheres sexualmente ativas no climatério devem tornar a questão da sexualidade um assunto natural nos grupos e sensibilizá-las para realização de exercícios com ênfase no fortalecimento pélvico.
EFEITOS DA HIDROTERAPIA EM PACIENTES PORTADORES DE SÍNDROME DE DOWN: UMA REVISÃO DE LITERATURA
Authors: Araújo Adlla de Oliveira , Santos Eduarda Ribeiro dos , Abdalla Matheus Andrade , Araújo Nicolly Brasileiro , Souza Julia Andrade de , Franchi Uerley Magalhães
Published: November 2024

A Síndrome de Down é uma condição genética que pode afetar o desenvolvimento físico, cognitivo e emocional de indivíduos. Para pessoas com essa síndrome, a hidroterapia tem se mostrado uma abordagem terapêutica eficaz, oferecendo uma variedade de benefícios que podem melhorar significativamente sua qualidade de vida. Nesta revisão de literatura, exploraremos os efeitos positivos da hidroterapia em pacientes portadores de Síndrome de Down, destacando como essa forma de terapia aquática pode promover o bem-estar físico, sensorial, emocional e social desses indivíduos.
DAS IMPLICAÇÕES DA PNEEPEI NA EDUCAÇÃO À INCLUSÃO DE ALUNOS COM DEFICIÊNCIAS: O PAPEL DOS PROFISSIONAIS DE APOIO ESCOLAR EM ESCOLA REGULARES
Authors: Santos Larissa Kelle Costa dos , Ribeiro Mílvio da Silva
Published: November 2024

A Política Nacional de Educação Especial na Perspectiva da Educação Inclusiva (PNEEPEI), direcionou os estudantes com necessidades educacionais especiais para escolas e classes regulares, demandando uma reorganização do espaço escolar para acomodar esse público. O objetivo do estudo foi analisar as implicações da PNEEPEI na inclusão de alunos com necessidades educacionais especiais em escolas regulares, com foco no papel dos Profissionais de Apoio Escolar (PAE). A pesquisa baseia-se em uma revisão bibliográfica de estudos e documentos relacionados à PNEEPEI e à inclusão de alunos com necessidades educacionais especiais. A PNEEPEI trouxe avanços significativos na inclusão de alunos com necessidades educacionais especiais, mas também desafios, principalmente no que tange a atuação e formação dos profissionais de apoio escolar, nesse sentido é crucial discutir as políticas públicas atuais considerem a necessidade de um suporte mais consistente e integrado para promover verdadeiramente uma educação inclusiva.
ASPECTOS ÉTICOS DA ESTABILIZAÇÃO PROTETORA EM ODONTOPEDIATRIA
Authors: Martins Amanda Correia , Dias Francilena Maria Campos Santos , Silva Karime Tavares Lima da
Published: November 2024

A odontopediatria desempenha um papel crucial na promoção da saúde bucal infantil,  e a estabilização protetora é uma prática essencial para garantir o tratamento  adequado das crianças. Este trabalho tem como objetivo analisar os aspectos éticos  envolvidos na estabilização protetora, enfatizando a importância do consentimento  informado, da comunicação efetiva e do respeito à dignidade do paciente. A  metodologia adotada inclui uma revisão bibliográfica de artigos relevantes e diretrizes  éticas na odontologia, bem como entrevistas com profissionais da área para  compreender suas percepções sobre a prática ética. Os resultados evidenciam que a  maioria dos odontopediatras reconhece a necessidade de uma abordagem ética que  considere o bem-estar da criança e a construção de um ambiente seguro e acolhedor.  Além disso, foram identificadas lacunas na formação acadêmica em relação à ética,  sugerindo a necessidade de maior ênfase nos currículos. A pesquisa aponta que o  consentimento informado, a empatia e a comunicação são pilares fundamentais para  a prática ética na estabilização protetora. A maioria dos profissionais entrevistados  concorda que a ética deve ser um componente central na relação com as crianças e  suas famílias, assegurando que todas as intervenções sejam compreendidas e  aceitas. Assim, este estudo contribui para a reflexão sobre as práticas odontológicas,  destacando a relevância de uma formação ética sólida para os profissionais, além de  sugerir melhorias na comunicação e no envolvimento dos responsáveis nos cuidados  de saúde bucal infantil.
A INFLUÊNCIA DOS LAUDOS PERICIAS E ESTUDOS SOCIAIS NAS DECISÕES JUDICIAIS SOBRE BENEFÍCIOS PREVIDENCIÁRIOS: ANÁLISE DA DESVALORIZAÇÃO DAS PROVAS MATERIAS NA COMPROVAÇÃO DA QUALIDADE DE SEGURADO ESPECIAL
Authors: Ribeiro Ariany Vital , Lima Josefa Maria Eduarda Dias , Guimarães Pedro Fernando Borba Vaz
Published: November 2024

Social security law plays a fundamental role in ensuring that beneficiaries under the General Social Security System have access to benefits, including special insured persons, such as rural workers, artisanal fishermen, spouses, children over 16 years old, indigenous people, and vegetal extractivists who operate under a family economy system. To receive benefits, these insured individuals must prove their status through initial material evidence, complemented by testimonial evidence. However, the lack of uniformity in judicial decisions regarding what qualifies as initial material evidence and the overvaluation of testimonial evidence has led to legal uncertainty. This imbalance undermines the principle of the judge’s motivated free conviction and may result in unequal decisions, violating the principle of equality. This study highlights the need for clearer and more consistent criteria to ensure fair and equitable social security decisions for special insured persons.
O ENFRENTAMENTO DA VIOLÊNCIA CONTRA A CRIANÇA E O ADOLESCENTE APÓS A LEI N° 14.344/2022 (LEI HENRY BOREL)
Authors: Oliveira Ana Luísa Carvalho de , Seabra Marcos Antônio , Leal Eduardo César Russo
Published: November 2024

This article addresses Law No. 14.344/2022, known as the Henry Borel Law, enacted to strengthen the protection of children and adolescents who are victims of domestic violence. Initially, it discusses the concept of child violence, identifying its various forms— physical, psychological, sexual, and neglect—and their implications for the victims' development. The study analyzes the context of the law's creation, motivated by the need for a more effective legislative response following emblematic cases of violence, such as that of the boy Henry Borel, and details the main provisions of the legislation, including protective measures and penalties for aggressors. The research also explores the impacts of the Henry Borel Law, highlighting the strengthening of the protection network and social awareness about child violence. However, the article discusses the challenges faced in implementing the law, such as the lack of infrastructure and resources, the disarticulation between protective agencies, and cultural barriers that hinder reporting and addressing violence. It concludes that despite the significant advancements provided by the Henry Borel Law, its effectiveness depends on a collective commitment between the state and society to overcome the practical and cultural limitations that still persist in combating violence against children and adolescents. The scientific article emphasizes the importance of a continuous effort to ensure a safe and healthy environment for the development of future generations.
PRIMEIROS CUIDADOS COM POTROS
Authors: Silva Gabriely Santos , Gallo Marco Aurélio
Published: November 2024

The care of equine neonates is essential to ensure good quality of life and the well-being of the animal. After extensive research, it became evident that analyzing data that informs and illustrates the importance of special care and proper management of newborn foals is highly valuable. These studies show that the results obtained can contribute to understanding prior evaluation, prevention, and observation of conditions or ailments that, if neglected, could lead to potential comorbidities in the animals. Additionally, there is a significant need to analyze and adhere strictly to all care practices in managing the pregnant mare, as these directly impact the foal's outcomes, whether positive or negative.
INTELIGÊNCIA ARTIFICIAL NO SETOR ELÉTRICO: MONITORAMENTO DA QUALIDADE DA ENERGIA POR MEIO DE REDES NEURAIS
Authors: Nicolau Igor da Silva , Coelho Stênio de Sousa
Published: November 2024

Este trabalho tem como objetivo investigar o uso de técnicas de aprendizado profundo para o monitoramento e classificação de distúrbios de qualidade de energia, com foco em redes LSTM e CNN. Através de dados simulados, os modelos são avaliados em termos de precisão e robustez, especialmente em ambientes ruidosos, e comparados com métodos convencionais, como K-Nearest Neighbors (KNN) e Naive Bayes (NB). A inovação deste estudo reside na aplicação de redes neurais profundas para capturar características temporais e espaciais dos distúrbios, resultando em maior acurácia e eficiência na detecção de eventos complexos de qualidade de energia. Os resultados esperados demonstram que as redes LSTM e CNN são superiores em termos de resiliência e precisão, apresentando-se como alternativas promissoras para o monitoramento avançado em sistemas elétricos.
OS IMPACTOS DAS LICENÇAS ESTENDIDAS NAS LICENÇAS-MATERNIDADE DAS TRABALHADORAS CELETISTAS
Authors: Aires Luana Sávia A , Falcão Maurin Almeida
Published: November 2024

TEMA: Busca o presente trabalho apresentar um estudo sobre os efeitos na dilatação dos prazos das licenças do Programa Empresa Cidadã na licença-maternidade constitucional das trabalhadoras celetistas no Setor Privado. OBJETIVOS: analisar os impactos positivos e negativos para as mulheres da extensão dos prazos das licenças por nascimento de filho, estabelecidas na Lei nº11.770/2008. METODOLOGIA: a pesquisa é qualitativa de natureza exploratória e o método de abordagem do problema descritivo dos modos de concessão e custeio das licenças estendidas do Programa Empresa Cidadã, baseados nos relatórios da ANDI Comunicação e Direito (2021) e Family Talks and 4Daddy (2022), levantamento histórico e revisão bibliográfica do instituto nos últimos cinco anos. RESULTADOS: os achados indicam que a extensão de sessenta dias para a mãe é benéfica ao aleitamento materno até os 6(seis) meses da criança, porém a amamentação não é exclusiva, os quinze dias concedidos ao pai, embora acarretem melhor adaptação à nova rotina doméstica, ainda é inóspita à carga de responsabilidade materna. Quanto à natureza contributiva, é baixa a adesão das empresas aptas à inscrição, além de o acesso ser impactado não só pela desigualdade de tratamento das empresas e dos gêneros, como também por classe social e raça.  CONCLUSÃO: As licenças estendidas são um plus à formação de vínculo entre pais e filhos, contudo, os termos para os cuidados nos primeiros meses da criança não se limitam apenas aos prazos das licenças, assim como não garantem às trabalhadoras, ao término das garantias, a permanência no trabalho.
Reconceptualizing Teachers as First Responders
Authors: Sam Cecile , Gupton Jarrett
Published: November 2024

This conceptual paper builds upon prior ideas of teacher work in the United States to include the role of “first responder” and highlights how this idea can change the current approach to understanding their work experience. We answer the following questions: 1. Why should we include first-responders as part of our conceptualization of teachers and the work that they do? 2. How would this reconceptualization change how we currently understand the nature of the teacher work experience?  This paper expands upon existing literature of teachers, especially those who work with vulnerable populations.
DBT Skills Training Groups for School Personnel Working in High-Need Schools
Authors: Shernoff Elisa , Ruork Allison , Kleiman Evan , Nadeem Erum , Rizvi Shireen
Published: November 2024

The COVID-19 pandemic presented unprecedented challenges for school communities with long term impacts still unknown. School personnel working in high need, low wealth schools are uniquely at risk for pandemic-related stress given extensive changes to their work life and concerns regarding student trauma exposure. We delivered DBT skills training to 39 school personnel (89% female, mean years of experience was 18.49 [SD = 7.88]). Close to 20% of the sample reported moderate-to-severe anxiety, depression, and stress and substantial impact of COVID-19 on loved ones. Multilevel regressions indicated significant decreases in stress between the 1st-2nd sessions attended (p = .004), and the 3rd-6th sessions attended (p = .04). Sessions 7-8 were not associated with significant decreases in stress (p = .51). Study limitations, implications, and conclusions are discussed.
Rumination as a Moderator of the Relation between Childhood Adversity Exposure and College Students’ Psychological Distress
Authors: Alligood Brittany , Fletcher Anne , Vrshek-Schallhorn Suzanne , Jensen Michaeline
Published: November 2024

American college students (N = 598) completed self-report questionnaires assessing rumination, psychological distress while attending college (general distress, anhedonic depression, anxious arousal), and exposure to specific types of childhood adversity (i.e., emotional abuse, sexual abuse, physical abuse, emotional neglect, and physical neglect). Latent Moderated Structural Equation Modeling indicated that 1) rumination was associated with all three indicators of psychological distress and 2) rumination moderated associations between childhood adversity exposure and college students’ reports of general distress and anxious arousal such that associations were strongest at higher levels of rumination and weaker at lower levels of rumination. Implications regarding higher education professionals’ efforts to support college student well-being are discussed.
Financial Fraud Detection Study - Based on Logit Model
Authors: Wan Yangyang
Published: November 2024

The problem of financial fraud has always been a key issue of concern for researchers at home and abroad, and financial fraud of listed companies occurs from time to time at home and abroad, which produces a huge loss of interest for investors as well as the downturn and instability of the capital market, for this reason, it is necessary to carry out a study on the detection of financial fraud. This paper analyzes the financial fraud detection of Chinese listed companies by establishing a Logit model, firstly, obtain the financial statement sample data of Chinese listed companies from CSMAR, and divide the sample into training set and test set with the ratio of 9:1 to preprocess the sample data and fill in the missing values; secondly, this paper selects the financial statement data, and based on the previous research, selects the characteristics that are related to the risk of financial fraud and constitute the risk of financial fraud. high features, and constitute the feature indicators for financial fraud detection; again, since detecting financial fraud is a binary classification problem, the sample is divided into fraudulent companies and normal companies, so this paper studies the financial fraud problem through the discrete choice model in the econometric model, constructs a Logit model, conducts a goodness-of-fit test on the sample data of CSMAR, and estimates the parameters using the method of maximum likelihood estimation ; finally, the test set data is used to test the model's ability to predict financial fraud.
Isolation and Identification of Bacterial Pathogens from Blood Cultures in a Tertiary Care Hospital and Their Clinical Correlation
Authors: Satapathy Dr. Satyaram , Mandavi Dr. Dhanuram , Panda Dr. Dhiren Kumar , Samal Dr. Debasish
Published: November 2024

Objective: This study aimed to isolate and identify bacterial pathogens from blood cultures of patients with suspected bloodstream infections (BSIs) in a tertiary care hospital, analyze their antimicrobial susceptibility patterns, and establish clinical correlations. Methods: A cross-sectional study was conducted in the Microbiology Department of a tertiary care hospital. Blood samples from 60 patients were collected aseptically, processed using BACTEC, and cultured on blood and MacConkey agar. Bacterial isolates were identified based on colonial morphology, Gram staining, and biochemical tests. Antibiotic susceptibility testing was performed using the modified Kirby-Bauer disk diffusion method according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: The overall culture positivity rate was 26%, with higher positivity among female patients (31.57%) and neonates or infants under six months (26%). Klebsiella pneumoniae was the most frequently isolated pathogen (53.33%), followed by Staphylococcus aureus (20.00%), Escherichia coli (13.33%), and Citrobacter species (13.33%). Klebsiella pneumoniae showed high resistance to ceftazidime and piperacillin, while remaining sensitive to cefoperazone and tobramycin. Staphylococcus aureus isolates were resistant to penicillin and erythromycin but sensitive to vancomycin and cefazolin. The prevalence of multidrug resistance among isolates underscores the need for targeted empirical therapy. Conclusion: Klebsiella pneumoniae emerged as the primary pathogen in BSIs, with significant resistance to commonly prescribed antibiotics. These findings highlight the necessity for enhanced infection control measures, especially in NICUs, and the implementation of local antibiograms to guide effective antibiotic therapy and mitigate resistance trends. Further research across multiple centers is recommended to validate these findings and inform broader clinical guidelines.
Leading Change Through Compassion: Minimizing Stress and Maximizing Outcomes
Authors: Westover Jonathan
Published: November 2024

Leading organizational change initiatives effectively while minimizing stress on stakeholders is a critical yet challenging aspect of transformational leadership. This practitioner-focused research brief examines evidence-based strategies for navigating change through a compassionate lens. Drawing from academic studies in change management, leadership, and occupational stress, key frameworks are explored for understanding sources of change-related anxiety and building understanding, dialogue, and involvement to cultivate buy-in. Specific tactics outlined include setting strategic context, validating emotions, pacing milestones appropriately, and involving teams meaningfully in problem-solving. Industry examples demonstrate tangible benefits such as lower perceived uncertainty, higher post-change engagement, and decreased stress-related absences when combining an empathetic approach with transparency and support. The brief concludes by asserting leading with empathy and viewing change as a collaborative journey can strengthen resilience and culture during times of organizational transformation.
Mental Health Practices for South Asian Cisgender Women Survivors of Domestic Violence in the United States
Authors: Millner Uma Chandrika , Bhandari Shreya
Published: November 2024

At present, little is known about best practices in mental health for cisgender South Asian women in the United States who experience domestic violence. The authors will review the diversity of South Asian communities, describe the prevalence of domestic violence and its impact on mental
health, and explicate the myriad systems that serve as facilitators and barriers in help seeking within neocolonial contexts in which South Asians are minoritized and othered. We have collated the scant literature and provided concrete recommendations for best practices focused on connections,
collectives, and communities to meet the diverse needs of South Asians in the United States while navigating the systems of care provided by South Asian domestic violence agencies and mental health services.
Milk Value Chain Analysis: The Case of Urban and Peri-Urban Areas of Ambo and Dendi Districts, West Shewa Zone, Oromia National Regional State, Ethiopia
Authors: Tura Kemer , Fita Lemma
Published: November 2024

This study was aimed at analyzing value chain of milk in Urban and Peri – Urban areas of Ambo and Dendi districts of West Shewa Zone. The study made use of both primary and secondary data collected from 146 smallholder farmers, 30 consumers, 10 Hotels and Cafeterias and 2 primary milk cooperatives through application of individual interview schedules, focus group discussions and key informant interview. The analysis was made using descriptive statistics and value chain analysis. The value chain analysis revealed that the major actors in the districts milk value chains are input suppliers, milk producers, collectors, processors and consumers. Accordingly, the value chain activities in the chain were input supply, production, processing, marketing and consumption. Four milk marketing channels were identified and relative to all other fresh milk marketing channels, producers get a higher proportion of total gross marketing margin when they sell milk to cooperatives. Profitability analysis result for dairy production indicated that, a dairy producer obtains average gross margin of 83.65per improved cow per day, in the study areas which shows that dairy production was a profitable venture for smallholder dairy producers. Milk value chain in the study areas was hindered by shortage of feeds, continuous increasing price of feeds, poor AI service provision, poor supply of genetically improved cattle breeds, limited availability of credit services, limited extension service provision, poor feeding and animal husbandry practices, low level of market linkage among the value chain actors, absence of milk processing plant and non-market oriented milk production. Therefore, policy aiming at increasing farmers’ access to modern inputs, feed conservation practices, adequate training provision to AI technicians, developing and improving infrastructure, cooperative development and improving extension services are recommended to accelerate the milk value chain’s development in the study areas.
Strategies for Achieving Competitive Advantage in Transformative Islamic Education
Authors: Al As'adie Mohammad Faried Wajdie , Hasanah Siti Nur Hidayatul
Published: November 2024

This study aims to identify and analyze the strategy for creating a competitive advantage in the transformative Islamic education service industry at MAN 1 Jombang. Transformative Islamic education is an educational approach that focuses on developing students' character, morals and spirituality to achieve positive transformation in themselves. As an Islamic education institution, MAN 1 Jombang has adopted this approach and strives to attract prospective and retain existing students. This study used qualitative methods with data collection techniques in the form of interviews, observation and document analysis. The results showed that MAN 1 Jombang had implemented several strategies to create a practical competitive advantage, namely: 1) the establishment of a positive image of the institution, 2) improving the quality of education, 3) promotion through social media, and active involvement with the local community. Competitive advantage focuses on the many students who register and are enrolled and the positive changes students can achieve regarding human resource quality, character, and spirituality.
STRUCTURAL CAPITAL EFFICIENCY AND FINANCIAL PERFORMANCE
Authors: AKINBODE, FEYISAYO AANUOLUWAPO  , OKEWALE, JOEL ADENIYI  , ADEDEJI, SAMUEL BABATUNJI
Published: November 2024

The study examined how structural capital efficiency affected Nigerian publicly traded companies' financial results. It used a sample of Nigerian companies to examine the relationship between structural capital efficiency and important financial indicators, such as ROA and ROE. A descriptive study design was employed, utilizing an ex-post facto methodology. Twenty-two companies were purposefully chosen from a total of 151 publicly listed firms in Nigeria for this analysis, focusing on their financial statements. The sample included 11 manufacturing firms, 5 ICT companies, 3 health services providers, and 3 oil and gas enterprises, spanning a period from 2013 to 2022. The analysis made use of panel data techniques and a number of post-estimation tests, such as random effects models, fixed effects, and Ordinary Least Squares (OLS). In order to maintain accuracy and handle endogeneity concerns, the SGMM was also utilized.  The results of the study indicated that while SCE had a positive, non-significant influence on ROE (p-value = 0.3886, β = 0.168, t-value = 0.8638), it had a significant positive effect on ROA (p-value = 0.0029, β = 0.0206, t-value = 3.0141). These results showed that while structural capital efficiency had a favorable but statistically insignificant effect on ROE, it greatly increased ROA.  The study's conclusions suggest that management should give structural capital development top priority in order to enhance financial results since it has a positive effect on the financial performance of Nigerian businesses.
TRADE LIBERALIZATION AND ECONOMIC GROWTH IN SELECTED WEST AFRICAN COUNTRIES
Authors: OSUNAIYE DAVID SOLOMON  , MARCELLINA ODUH  , ILEMONA ADOFU  , OBADIAH JONATHAN GIMBA
Published: November 2024

This research examines the relationship between trade liberalization and economic growth in selected   West   African   countries   (Cote d‟Ivoire, Ghana and Nigeria)   the  choice   of these countries  is  as   a  result   of  steady   GDP  growth  over  the years, using secondary data in a multivariate   panel    framework   for   the  period   1976 - 2023.   The  main objective  was to establish  the   effects   of  trade  liberalization   on economic  growth  in these  countries. The Autoregressive    Distributed     Lag   (ARDL)   bound   tests and   other  diagnostic   tests  were   employed   for  data estimation.   The    results   indicated    long run    relationship    between    trade   liberalization   and economic   growth  in Cote d‟Ivoire, Ghana  and  Nigeria.  The   relationship  is   positive  and  significant  for  the  three   countries.  In  the long run, the combination of   other macroeconomic variables like investment,   human capital,   net inflow  of FDI and the exchange  rate   complement   the    contribution     of     trade   to    economic growth.   Therefore,     these    countries      should     promote      appropriate    trade   policies devoted   to    foster  increased   local   production   of  manufactured  and  agricultural goods to    reduce  importation    and  stimulate  exports,   as a  strategy  to  boost  economic  growth
ANALISIS LOYALITAS PASIEN BERDASARKAN INDIKATOR KINERJA RAWAT INAP PASCA PANDEMI COVID-19
Authors: Azmi Ulil , Junus Darmawati , Samad Mohammad Ardani , Pratiwi Reski Dewi
Published: November 2024

Indikator Kinerja Rawat Inap merupakan gambaran untuk mengetahui tingkat pemanfaatan, mutu, efisiensi pelayanan rawat inap dan efisiensi penggunaan tempat tidur di rumah sakit. Maka untuk mengukur dan melihat hal tersebut dilihat dari loyalitas pasien. Apalagi disituasi pasca covid-19 ini, persentase keterisian tempat tidur menurun di beberapa wilayah di Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui loyalitas pasien berdasarkan indikator kinerja rawat inap pasca pandemi covid-19 di Rumah Sakit Tk. II 14.05.01 Pelamonia Makassar. Jenis penelitian yang digunakan dalam penelitian ini adalah desain penelitian deskriptif dengan pendekatan kuantitatif. Penelitian ini dilakukan di ruang rawat inap dengan sampel sebanyak 300 responden yang ditentukan melalui teknik purposive sampling. Data dalam penelitian ini diperoleh melalui kuesioner dan data sekunder rumah sakit. Hasil penelitian menunjukkan bahwa loyalitas pasien berdasarkan indikator Bed Occupancy Rate (BOR), Average Length Of Stay (ALOS), Turn Over Internal (TOI), Bed Turn Over (BTO), Net Death Rate (NDR) dan Gross Death Rate (GDR) berada pada kategori baik dengan jawaban responden ≥62,5%. Disarankan kepada pihak rumah sakit agar meningkatkan lagi kinerjanya khususnya kinerja rawat inap agar pasien tertarik untuk melakukan kunjungan ulang dan tetap menggunakan pelayanan yang ada di Rumah Sakit Tk. II 14.05.01 Pelamonia Makassar.
Pengaruh Enabling Factors terhadap Perilaku Pencegahan Hipertensi pada Pra Lanjut Usia Berisiko di Puskesmas Tamalate Kota Makassar
Authors: Hijrah Hijrah , Asrina Andi
Published: November 2024

WHO berkomitmen untuk menurunkan tingkat hipertensi pada lansia dengan fokus pada pendidikan kesehatan yang kuat, promosi gaya hidup sehat, dan pemberian akses yang lebih baik terhadap layanan kesehatan. Meningkatkatnya kesadaran akan risiko hipertensi, masyarakat akan lebih cenderung mengadopsi gaya hidup sehat, termasuk diet yang seimbang dan olahraga teratur, serta akan lebih aktif dalam melakukan pemeriksaan tekanan darah rutin.  Masyarakat yang telah berusia lansia, menjadi rentan mengalami penyakit hipertensi, akibat dari pembuluh arteri yang kurang fleksibel lagi  Dalam tiga tahun terakhir, Puskesmas Tamalate memiliki jumlah pasien dengan hipertensi tertinggi. Tahun 2021, ada 11.963 kasus hipertensi; tahun 2022, ada 12.874 kasus; dan tahun 2023, dari Januari hingga September, ada 10.158 kasus hipertensi.  Penelitian ini merupakan jenis penelitian kuantitatif yang dirancang sebagai studi cross-sectional. Teknik Pengumpulan sampel dilakukan menggunakan Teknik Sampling purposive terdiri dari 172 individu orang pra lanjut usia (45-59 tahun) yang berisiko mengalami hipertensi. Hasil Penelitian didapatkan tidak ada pengaruh faktor pemungkin/ enabling factors ketersediaan dan akses pelayanan kesehatan (Nd); Ada pengaruh sarana dan prasarana (0,026) terhadap perilaku pencegahan hipertensi pada pra lanjut usia berisiko. Perlu adanya kontribusi kepala dan seluruh jajaran staf Puskesmas Tamalate Kota Makassar agar sedapat mungkin menyediakan akses pelayanan kesehatan juga sarana prasarana yang menunjang kebutuhan dalam upaya pencegahan pra lansia terhadap risiko kejadian hipertensi.
Analisis Sistem Pengendalian Internal Resi Kas di RSUD Kepohbaru, Bojonegoro
Authors: Handayani Sutri , Wardana Faizal Wahyud , Masyahdi
Published: November 2024

Pentingnya sistem pengendalian internal dalam penerimaan kas untuk melindungi dari hal-hal yang merugikan uang tunai. Tujuan penelitian ini adalah untuk mengetahui dan menganalisis bagaimana sistem informasi pengendalian internal dan metode penerimaan kas diterapkan di RSUD Kepohbar u Bojonegoro. Metode penelitian yang digunakan adalah kualitatif. Pengambilan sampel menggunakan metode purposive sampling dengan 3 karyawan di departemen keuangan penerimaan kas di RSUD Kepohbaru. Pengumpulan data dengan melakukan observasi, wawancara, dokumentasi, studi pustaka. Analisis data penelitian ini menggunakan reduksi data, penyajian data, penarikan kesimpulan. Hasil penelitian menunjukkan bahwa Pelaksanaan Penerimaan Tunai di RSUD Kepohbaru dapat dikategorikan baik. Dan hasil Penelitian Sistem Pengendalian Internal di RSUD Kepohbaru sangat baik karena telah memenuhi lima elemen yang ditetapkan oleh COSO.
Peran Coder Terkait Keakuratan Pengkodean ICD-10 Pada Pelaksanaan Sistem INA-CBG’s Rumah Sakit TK. II 14.05.01 Pelamonia Makassar
Authors: Ekawati Dian , Nuryadin Adriyana Adevia , Windarti Sriyani , Zulfikar Andi
Published: November 2024

Dalam pelaksanaan JKN, kegiatan coder klaim BPJS Kesehatan dimulai dengan menerima dokumen rekam medis pasien BPJS dari unit assembling. Kemudian, jika ada kesalahan, dokumen tersebut dipisahkan dan dikirim ke bagian yang terkait untuk diperbaiki terlebih dahulu. Selanjutnya adalah menentukan kode penyakit dan prosedur medis. Tujuan penelitian, untuk mengetahui peran coder terkait keakuratan pengkodean ICD-10 pada pelaksanaan sistem INA-CBG’s di Rumah Sakit TK.II 14.01.05 Pelamonia Makassar. Metode ini menggunakan penelitian kualitatif. Pengumpulan data melakukan dengan wawancara kepada Kepala Casemix, Kepala Rekam Medis, Petugas Coder dan Petugas Rekam Medis. Hasil dan Kesimpulan  menunjukkan bahwa petugas rekam medis dan petugas coder rata-rata memiliki pengalaman yang mencukupi untuk menjalankan proses pengkodean klaim BPJS, walaupun masih terdapat beberapa permasalahan yang biasa dialami petugas. Petugas coder sudah mendapatkan pendidikan yang sesuai tentang pengkodean dan beberapa petugas pernah mengikuti seminar INA-CBG’s sehingga mengetahui apa itu INA-CBG’s dan juga fungsinya. Namun, masalah yang paling umum yang dihadapi petugas coder termasuk penulisan diagnosis penyakit yang sering disingkat, perbedaan antara tindakan yang ditulis dan dilaporkan DPJP.
Small PLTS Off Grid 240 WP On Residential House Rooftop
Authors: Puspitasari Etik , Eko Yudiyanto  , Lisa Agustriyana  , Nila Alia
Published: November 2024

Small PLTS on residential rooftops are now being widely applied. It can contribute to using alternative energy to support government programs to save electricity costs. It can also be used as backup electricity when PLN power outage. The purpose of this research is to be able to calculate the use of electric power in residential homes, design and make small PLTS off grid 240 WP from the use of electric power, calculate BEP when the payback time of the total investment in the procurement of small PLTS 240 WP with DC and AC systems. 240 WP power on the rooftop of a residential house is carried out for a load of 8 lights AC with 6 watts and one fan. This research showed that the total daily electric power usage was 0.55 kWh/day or 16.5 kWh/month. The design of 240 WP PLTS on the rooftop of a residential house according to the total household electricity needs of 550 watts/day requires core equipment such as two solar panels (120 WP), one battery (12 V 100 Ah), Inverter (12 V to 220 V) = 1000 Watt or 1 kWh as much as one piece, SCC = 20 A as much as one piece. The results of making 240 WP PLTS on the rooftop of a residential house accorded to the total electrical power needs of the household. Break Even Point on this application of 240WP solar power PLTS on residential rooftops with 1300 V power will return capital in 19.5 years. Where the total investment cost of procuring 240 WP PLTS is Rp. 5,558,000, and the cost of electricity per month from the above load is Rp. 23,850 / month or Rp. 286,200 / year.
Smoking–The Perilous Voyage of Periodontal Disease
Authors: Vishnu Sri Priya J  , Subair k  , Nanditha Chandran  , Hemalatha DM  , Albin Job  , Akshaya Pramod
Published: November 2024

There is compelling epidemiological evidence, both from cross-sectional and longitudinal research, suggesting that smoking is associated with a significantly elevated risk of periodontal disease. The statistics derived from patients who give up smoking provide more support for this evidence. The risk levels of these patients are comparable to those of nonsmokers. Several investigations have been carried out to explore the possible pathways through which smoking tobacco could predispose to periodontal disease. The findings suggest that smoking may impact the vasculature, humoral immune system, cellular immune and inflammatory systems, as well as have effects across the cytokine as well as the adhesion molecule. This review article describes about the various treatment modalities that enhances the cessation of smoking and the positive results seen in periodontium in quitting smoking.