bluuebunny/crossref_metadata_2025 huggingface dataset:
Value of Contrast-enhanced Magnetic Resonance Imaging (MRI) in the
Diagnosis of Breast Cancer
Authors: Gonçalves Mateus Aquino , Pereira Bruna T.L. , Tavares Camila A. , Santos Taináh M.R. , da Cunha Elaine F.F. , Ramalho Teodorico C.
Published: May 2021

This review article aims to address the main features of breast cancer. Thus, the general
aspects of this disease have been shown since the first evidence of breast cancer in the world until the
numbers today. In this way, there are some ways to prevent breast cancer, such as the woman's lifestyle
(healthy eating habits and physical activities) that helps to reduce the incidence of this anomaly.
The first noticeable symptom of this anomaly is typically a lump that feels different from the rest of
the breast tissue. More than 80% of breast cancer are discovered when the woman feels a lump being
present and about 90% of the cases, the cancer is noticed by the woman herself. Currently, the most
used method for the detection of cancer and other injuries is the Magnetic Resonance Imaging (MRI)
technique. This technique has been shown to be very effective, however, for a better visualization of
the images, Contrast Agents (CAs) are used, which are paramagnetic compounds capable of increasing
the relaxation of the hydrogen atoms of the water molecules present in the body tissues. The most
used CAs are Gd3+ complexes, although they are very efficient, they are toxic to the organism. Thus,
new contrast agents have been studied to replace Gd3+ complexes; we can mention iron oxides as a
promising substitute.
Therapeutic Application of Melatonin in the Treatment of Melanoma: A Review
Authors: Fatemi Iman , Dehdashtian Ehsan , Pourhanifeh Mohammad H. , Mehrzadi Saeed , Hosseinzadeh Azam
Published: May 2021

Melanoma is an aggressive type of skin cancer, which is responsible for more deaths
than nonmelanoma skin cancers. Therapeutic strategies include targeted therapy, biochemotherapy,
immunotherapy, photodynamic therapy, chemotherapy, and surgical resection. Depending on the
clinical stage, single or combination therapy may be used to prevent and treat cancer. Due to resistance
development during treatment courses, the efficacy of mentioned therapies can be reduced.
In addition to resistance, these treatments have serious side effects for melanoma patients. According
to available reports, melatonin, a pineal indolamine with a wide spectrum of biological potentials,
has anticancer features. Furthermore, melatonin could protect against chemotherapy- and radiation-
induced adverse events and can sensitize cancer cells to therapy. The present review discusses
the therapeutic application of melatonin in the treatment of melanoma. This review was carried
out in PubMed, Web of Science, and Scopus databases comprising the date of publication period
from January 1976 to March 2021.
Does Proctologic Surgery Really Influence Sexual Behaviors?
Authors: Sturiale Alessandro , Fabiani Bernardina , Dowais Raad , Porzio Felipe Celedon , Gallo Gaetano , Martellucci Jacopo , Menconi Claudia , Morganti Riccardo , Naldini Gabriele
Published: May 2021

Introduction:

The percentage of the heterosexual population that has experienced and
regularly has anal intercourse ranges from 20% to 35% in the USA. This practice increases to 95%
in certain populations, including lesbian, gay, bisexual, and transgender people. Due to the lack of
data in the literature about the effect of proctologic surgery on anal intercourse, this study aimed to
assess the impact of this surgery on sexual behavior in both genders.

Materials and Methods:

From March 2016 to February 2018, an anonymous questionnaire was
submitted to all patients aged >18 who had undergone proctologic surgery in one of two surgical
units at tertiary referral centers and was assessed independently of gender. The exclusion criteria
were incomplete healing and <3 months follow-up.

Results:

In total, 929 patients answered the questionnaire in full. The overall prevalence of preoperative
anal intercourse was 22.5%. The rate of anal intercourse among men was 16.7%, while
among women, it was 28.9%. The overall postoperative rate of anal intercourse was 11.8%. The
rate of postoperative anal intercourse among those who regularly engaged in anal intercourse preoperatively
was 52.6%, with a 47.4% rate of non-completion (p <0.0001). The experiences reported
during intercourse after surgery were mainly pain, stiffness, and partner discomfort.

Conclusion:

Considering the statistically significant postoperative AI abandonment rate following
all types of proctologic surgery, the surgeon has a duty to both treat the disease and to inform the
patient about the possible consequences regarding its influence on anal intercourse.
Qigefang Inhibits Migration, Invasion, and Metastasis of ESCC by Inhibiting Gas6/Axl Signaling Pathway
Authors: Wu Zhongbing , Zhao Yang , Yu Fuyang , Shi Huijuan , Li Jing
Published: May 2021

Background:

In recent years, there is an increasing interest in using Traditional Chinese
Medicine (TCM) and their patents for the treatment of cancers. Qigefang (QGF) is a TCM formula
and has been used for the treatment of metastatic esophageal cancer in China. However, its therapeutic
effect on tumors and its mechanism of action is largely unknown. The aim of this study is to
explore the role of QGF in the treatment of metastasis of Esophageal Squamous Cell Carcinoma(
ESCC).

Methods:

Human esophageal carcinoma cell line KYSE150 was used for this study. CCK-8 assay
was used to determine the cytotoxicity of QGF. The KYSE150 cells were treated with QGF to determine
its effect on cell migration (cell scratch assay and imaging) and invasion (Transwell system
based with Matrigel assay). Western blotting was used to investigate the effect of QGF on relevant
molecules of signaling pathways. A mouse model of lung metastasis of esophageal cancer was
established by injecting the KYSE150-Luc cells through the tail vein. A small animal imaging system
was used to observe tumor metastasis in the mice.

Results:

QGF reduced cell migration and invasion of KYSE150 cells. QGF significantly inhibited
lung metastasis in nude mice. Further study revealed that the expression of Growth arrest-specific
6 (Gas6), Anexelekto (Axl), N-Nuclear factor-kappa B (NF-κB) and matrix metalloproteinase-9
(MMP-9) proteins were decreased both in vitro and in vivo upon treatment with QGF.

Conclusion:

QGF could prevent invasion and metastasis of esophageal cancer by inhibiting the
Gas6/Axl signaling pathway.
Prenatal muscle forces are necessary for vertebral segmentation and disc structure, but not for notochord involution in mice
Authors: Levillain A , Ahmed S , Kaimaki D-M , Schuler S , Barros S , Labonte D , Iatridis JC , Nowlan NC
Published: May 2021

Embryonic muscle forces are necessary for normal vertebral development and spinal curvature, but their involvement in intervertebral disc (IVD) development remains unclear. The aim of the current study was to determine how muscle contractions affect (1) notochord involution and vertebral segmentation, and (2) IVD development including the mechanical properties and morphology, as well as collagen fibre alignment in the annulus fibrosus. Muscular dysgenesis (mdg) mice were harvested at three prenatal stages: at Theiler Stage (TS)22 when notochord involution starts, at TS24 when involution is complete, and at TS27 when the IVD is formed. Vertebral and IVD development were characterised using histology, immunofluorescence, and indentation testing. The results revealed that notochord involution and vertebral segmentation occurred independently of muscle contractions between TS22 and TS24. However, in the absence of muscle contractions, we found vertebral fusion in the cervical region at TS27, along with (i) a displacement of the nucleus pulposus towards the dorsal side, (ii) a disruption of the structural arrangement of collagen in the annulus fibrosus, and (iii) an increase in viscous behaviour of the annulus fibrosus. These findings emphasise the important role of mechanical forces during IVD development, and demonstrate a critical role of muscle loading during development to enable proper annulus fibrosus formation. They further suggest a need for mechanical loading in the creation of fibre-reinforced tissue engineering replacement IVDs as a therapy for IVD degeneration.
Pengaruh Penerapan Sistem E-Filling, Sanksi Perpajakan, Biaya Kepatuhan dan Pengetahuan Perpajakan Terhadap Kepatuhan WPOP pada KPP Pratama Badung Utara
Authors: Syafira Izra
Published: May 2021

This study aims to empirically test the effect of the application of e-filling system, tax sanctions, compliance costs and tax knowledge on the compliance of private taxpayers. The method of analysis used in this study is multiple linear regression analysis. The method of sampling taxpayers using the slovin formula, with the taxpayer sample used is as many as 100 respoden. The sample determination method uses a simple random sampling method. The results of this study showed that variable application of e-filling (X1) positively and significantly affects the compliance of private taxpayers. This is evidenced by the significance result of 0.000<0.05. Tax sanctions (X2) have a positive and significant effect on the compliance of private taxpayers. This is evidenced by the significance result of 0.001<0.05. Compliance costs (X3) have a positive and significant impact on the compliance of private persons taxpayers. This is evidenced by the significance result of 0.000<0.05. Tax knowledge (X3) has a positive and significant effect on the compliance of private taxpayers. This is evidenced by the significance of 0.000<0.05.
Pengaruh Non Performing Loan (Npl) dan Return On Asset (ROA) Terhadap Penyaluran Kredit Lembaga Perkreditan Desa di Kecamatan Sukawati
Authors: Pranadhi I Made Waka Sapta Anggi , Bagiada Kompiang , Giri Ni Putu Rediatni
Published: May 2021

Lembaga Perkreditan Desa (LPD) memiliki peranan yang sangat besar terhadap ekonomi desa, karena LPD sebagai perantara untuk menghimpun dana dalam bentuk simpanan, dan menyalurkannya kembali dalam bentuk kredit. Penelitian ini bertujuan untuk mengetahui pengaruh Non Performing Loan (NPL) dan  Return on Asset (ROA) terhadap Penyaluran Kredit LPD di Kecamatan Sukawati secara simultan dan secara parsial. Metode penelitian dalam penelitian ini menggunakan metode kuantitatif sedangkan teknik analisis yang digunakan adalah analisis regresi linier berganda. Hasil analisis penelitian ini menyatakan bahwa NPL dan ROA secara simultan tidak berpengaruh signifikan terhadap Penyaluran Kredit LPD di Kecamatan Sukawati. NPL dan ROA secara parsial tidak berpengaruh signifikan terhadap Penyaluran Kredit LPD di Kecamatan Sukawati.
THE EFFECT OF ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION ON MALE SEXUAL HEALTH
Authors: Bingöl İzzet , Köker Yasin
Published: May 2021

Background: Anterior cruciate ligament (ACL) injuries are among the most
common ligament injuries having social, mental, and spiritual effects as
well as physical effects, reducing the quality of life. Sexual health
plays an important role inreproduction as well as in the physical,
intellectual, emotional, and social aspects of life. Aims: In this
study, we compare male patients with conservative and surgical treatment
after ACL rupture in terms of sexual health. Methods: The sexual health
statuses of 41 male patients diagnosed of ACL rupture followed by
conservative or surgical treatment were evaluated before treatment, in
the 6 months and at the 1 year after treatment and compared using the
International Index of Erectile Function-5 (IIEF- 5). Results: When the
mean IIEF-5 scores followed with surgery and conservative treatment were
compared at 6 months, it was observed that the scores of those receiving
surgical treatment were significantly lower (p = 0.005). When the mean
IIEF-5 scores at 1 year were compared, it was seen that the surgical
treatment scores were significantly higher. (p = 0.012). Conclusions:
This study has shown that surgical treatment for ACL rupture has more
positive effect on male sexual life in the long term compared to
conservative treatment.
COPHYLOGENETIC ANALYSES OF TRACHYMYRMEX ANT-FUNGAL SPECIFICITY: ‘ONE TO ONE WITH SOME EXCEPTIONS’
Authors: Beigel Katherine , Matthews Alix , Kellner Katrin , Pawlik Christine , Greenwold Matthew , Seal Jon
Published: May 2021

Over the past few decades, large-scale phylogenetic analyses of
fungus-gardening ants and their symbiotic fungi have depicted strong
concordance among major clades of ants and their symbiotic fungi, yet
within clades, fungus sharing is somewhat widespread among unrelated ant
lineages. These symbioses are thought to be explained by a diffuse
coevolution model within major clades. Understanding horizontal exchange
within clades has been limited by conventional genetic markers that lack
both interspecific and geographic variation. To examine whether reports
of horizontal exchange was indeed symbiont sharing or an issue of
employing relatively uninformative molecular markers, samples of
Trachymyrmex arizonensis and Trachymyrmex pomonae and
their fungi were collected from native populations in Arizona and
genotyped using conventional marker genes and genome-wide single
nucleotide polymorphisms (SNPs). Conventional markers of the fungal
symbionts generally exhibited cophylogenetic patterns that were
consistent with some symbiont sharing, but most fungal clades had low
support. SNP analysis, in contrast, indicated that each ant species
exhibited fidelity to its own fungal subclade with only one instance of
a colony growing a fungus that was otherwise associated with a different
ant species. This evidence supports a pattern of codivergence between
Trachymyrmex species and their fungi, and thus a diffuse
coevolutionary model may not accurately predict symbiont exchange. These
results suggest that fungal sharing across host species in these
symbioses may be less extensive than previously thought.
Comparative Analysis of Educational Programs for Training Social Pedagogues on the Example of Universities in Kazakhstan, Lithuania and Germany
Authors:   Al-Farabi Kazakh National University, Magauova Akmaral , Makhambetova Zhamilya ,   Al-Farabi Kazakh National University, Lukashova Svetlana ,   Suleyman Demirel University
Published: May 2021

Abstract. In the context of integration of national education systems into a single global educational space, the competency-based paradigm of education serves as the main for training competitive strategy specialists. The transition to competency-based educational standards of higher education involves the formation of students' professional competences for successful professional activity. The aim of the research is to study and analyse the experience of development of professional competences in the training of social pedagogues in Kazakhstan, Lithuania, and Germany. In this paper, the study and comparative analysis of the experience of forming professional competences in the training of social pedagogues in Kazakhstan, Lithuania and Germany are carried out. The research showed that during the period of study at the University in the specialty "Social pedagogy and self-cognition", it is necessary to introduce a competency-based approach aimed at the formation of professional competences for working in an inclusive education. As a result of the research, the nature and trends of training social pedagogues in three countries are identified, then general and special competences of social pedagogues are analysed; finally, the professional competences adopted by the world community are highlighted.
Creation of a Turkish University League Based on the Contribution of their Economics Departments to Economics Education
Authors: Yıldz Selim Baha , Alptekin Volkan , Selim Sibel
Published: May 2021

This study aims to measure the added value created by the economics departments of the universities in Turkey for students throughout their undergraduate education. For the analysis section, the minimum admission scores of the universities' economics departments for the years from 2000 to 2012 were used as input and the net average scores obtained in the economics tests of Public Personnel Selection Examination (PPSE) for the years from 2004 to 2016 were used as output. The data were normalized using the min-max method and the universities were ranked using the "Borda count" method. According to the results, Ankara University ranked the 1st, Hacettepe University the 2nd and Middle East Technical University the 3rd. The first six positions in the top ten ranking are held by the universities located in the capital, Ankara. This is attributed to various factors such as the long-established character of the universities in the capital city, availability and diversity of training courses and materials for PPSE, permanency of the academic staff, prevalence of standard daytime education in these universities, and the role of the capital as the seat of public institutions, resulting in greater motivation among students as they have more contact with senior government officials.
Prediction of Effective Permittivity of Foam-Polymer Materials
Authors:   National Research University of Electronic Technology, Moscow, Russia, Lavrov I.V. , Bardushkin V.V. ,   National Research University of Electronic Technology, Moscow, Russia, Yakovlev V.B. ,   National Research University of Electronic Technology, Moscow, Russia; Institute of Nanotechnology of Microelectronics of the Russian Academy of Sciences, Moscow, Russia, Bardushkin A.V. ,   National Research University of Electronic Technology, Moscow, Russia; LLC «Alphachip», Moscow, Russia
Published: May 2021

Porous plastics are used in various fields of industry, including radio- and electrotechnical fields. They are characterized by good heat- and sound isolating, dielectric and mechanical properties as well as by resistance to effect of various external factors during operation. The problem of estimation of effective permittivity of foam-polymer materials with a large volume fraction of pores, in particular, polyepoxide foam materials, has been considered. Two methods for solving it, both based on the matrix have been proposed. In the first method the matrix is considered as a polyepoxide binder, and the cavities filled with gas are taken as inclusions. In the second method the polyepoxide walls, separating cavities, are taken as inclusions, and gas filling cavities is considered as a matrix. To obtain the formulas for calculation, both methods use a generalized singular approximation of the theory of random fields. Based on the obtained expressions, the model calculations of the effective permittivity of a macroscopically isotropic foam material with a polymer binder based on E-20 and the cavities filled with freon, depending on the apparent density of the material, have been made. The calculations in the generalized singular approximations have been carried out for two of its variants: when the matrix was considered as a comparison medium; and, also by the self-consistent method. In the calculations using the second method two variants of the shape of the cells of the material have been considered: a weakly leaked or heavily leaked polyhedron. The calculated dependences obtained by all me-thods have shown the qualitative compliance with the experimental data.
Implementation Features of an Analog Multiplier Based on 5529 Series Structured ASIC
Authors:   SMC «Technological Centre», Moscow, Russia, Belostotskaya S.O. , Lukyanov A.A. ,   SMC «Technological Centre», Moscow, Russia, Roslyakov A.S. ,   SMC «Technological Centre», Moscow, Russia, Semenov A.N. ,   SMC «Technological Centre», Moscow, Russia, Fedorov R.A. ,   SMC «Technological Centre», Moscow, Russia
Published: May 2021

During the analog signals processing one of the key factors is the reduction of power consumption with high accuracy of signal processing. One way of solving this problem is the implementation of analog IP-blocks. PLLs, AGC, modulators often include the analog signal multipliers. In the paper, the principle of quadratic function cell operation has been described in detail. The analog signal multiplier has been constructed on the basis of the difference of squares arithmetic formula and the considered cell of the quadratic current function. On the basis of the elements of 5529 series structured ASIC, the analog signal multiplier has been simulated and its accuracy has been assessed. The resulting analog complex functional IP-block for signal multiplication is a part of the development strategy for 5529 series structured ASIC library.
Control and Decision-Making Support in a Personalized Insulin Therapy System
Authors:   National Research University of Electronic Technology, Moscow, Russia, Litinskaia E.L.
Published: May 2021

Insulin therapy automation is an actual research line in the glycemic control of diabetes mellitus type 1 patients. Development of closed-loop systems and methods will allow blood glucose maintaining in the physiological range. The work proposes the personalized insulin therapy system considered as a closed-loop control system based on feedback and external disturbances compensation principles. Automatic feedback-based glycemic control includes proportional reg-ulation of basal insulin infusion rate in relation to optimized thresholds inside the target range. To achieve bidirectional glycemic regulation the author proposes model predictive control for calculation of not only optimal profile of bolus infusion but also recommended corrective dose of carbohydrates. Besides, the comparative analysis of trends in measured and predicted profiles of blood glucose allows detecting and compensation of its unpredicted deviations. In silico testing of developed algorithms on nine virtual adults for 72 hours shows an ability for glucose maintaining in the target range for whole system operation time.
PENGEMBANGAN USAHA UMKM DI MASA PANDEMI MELALUI OPTIMALISASI PENGGUNAAN DAN PENGELOLAAN MEDIA DIGITAL
Authors: Raharja Sam'un Jaja , Natari Sari Usih
Published: May 2021

Pandemi Covid-19 telah melanda banyak negara, termasuk Indonesia. Covid-19 telah menimbulkan dampak di berbagai sektor termasuk Usaha Mikro Kecil dan Menengah diantaranya yakni turunnya jumlah penjualan. Kegiatan Pengabdian Pada Masyarakat dilakukan untuk memberi bimbingan dalam mengatasi dampak tersebut melalui penggunaan dan pengelolaan media digital yang sesuai. Dengan menggunakan dan mengelola media digital, diharapkan para pelaku usaha dapat menentukan jenis media digital yang tepat untuk produk yang dipasarkan, meningkatkan awareness serta ketertarikan masyarakat mengenai produk. Metode yang digunakan adalah pelatihan secara virtual menggunakan Zoom Meeting.  Materi kegiatan berupa ini adalah strategi penggunaan dan pengelolaan media digital, optimalisasi digital marketing serta branding produk untuk meningkatkan kemampuan pembuatan konten yang menarik, promosi serta sebagai media alternatif bagi pelaku usaha bidang jasa. Media digital yang digunakan antara lain Instagram, Facebook WhatsApp, GrabFood/Go-Food, Tokopediadan platform lainnya.Hasil kegiatan menunjukkan bahwa pelatihan dan bimbingan yang diberikan memberikan dampak positif bagi para pelaku usaha dengan adanya peningkatan pengetahuan tentang media digital, peningkatan pengetahuan berbagai media yang dapat digunakan dan adanya peningkatan keterampilan dalam penggunaan dan pengelolaan media digital dalam branding. Rekomendasi yang dapat disampaikan adalah adanya keberlanjutan program pembinaan bagi para pelaku usaha sehingga dapat menerapkan dan mengelola media digital secara optimal.
PENGUATAN PEMBERDAYAAN MASYARAKAT KOMUNITAS LESTARI FARM DALAM MENJAGA KETAHANAN PANGAN MASA PANDEMI COVID-19
Authors: Sagita Novie Indrawati , Deliarnoor Nandang Alamsah , Afifah Dian Fitriani
Published: May 2021

Komunitas Lestari Farm dibentuk untuk menghadapi situasi Pandemi Covid-19 dengan tujuan menjaga ketahanan pangan keluarga, meningkatkan ekonomi dan kesejahteraan warga. Komunitas ini melakukan kegiatan budidaya pertanian dan perikanan. Sejak komunitas terbentuk, keterlibatan warga dalam kegiatan budidaya masih rendah. Tujuan kegiatan ini dilakukan untuk menguatkan pemberdayaan masyarakat pada Komunitas Lestari Farm  dan dapat menguatkan komitmen anggota untuk mencapai tujuan bersama. Kegiatan penyuluhan penguatan pemberdayaan masyarakat dilakukan secara daring, mengingat situasi Covid-19 yang tidak memungkinkan tim dan peserta bertemu langsung secara tatap muka. Kegiatan ini diawali dengan tahap persiapan yakni penggalian data, dan ditindaklanjuti dengan kegiatan evaluasi mengenai keberlanjutan Komunitas Lestari Farm. Hasil dari kegiatan ini berupa  mendiskusikan faktor-faktor yang menyebabkan rendahnya partisipasi warga. Faktor tersebut disebabkan karena tidak dilaksanakannya tahapan pemberdayaan masyarakat sebagaimana mestinya, yang diawali dengan tahap formulation action plan yang tidak sesuai sehingga berdampak pada tahap implementation hingga tahap evaluasi. Solusi yang dihasilkan pada kegiatan ini  berupa penyusunan model penguatan pemberdayaan masyarakat Komunitas Lestari Farm, serta peningkatan kegiatan forum komunikasi yang saling menguatkan pengetahuan, ketrampilan dan memotivasi sesama anggota.
EDUKASI DARING TENTANG PENCEGAHAN COVID-19 PADA TOKOH MASYARAKAT DESA HAURPANGGUNG KABUPATEN GARUT
Authors: Rosidin Udin , Sumarna Umar , Eriyani Theresia , Noor Rohmahalia M
Published: May 2021

Saat ini seluruh negara disibukkan dengan masalah kesehatan masyarakat yaitu pandemi Covid-19. Data akhir tahun 2020 melaporkan bahwa kasus terus meningkat di seluruh dunia. Demikian juga di Indonesia di mana kasus terus naik dan Jawa Barat termasuk provinsi dengan kasus terbanyak. Haurpanggung salah satu desa di Kabupaten Garut merupakan daerah yang memiliki potensi tinggi penularan Covid-19. Hasil survei menunjukkan masih banyak masyarakat Haurpanggung yang mengabaikan protokol kesehatan. Selain itu, terdapat tiga area publik seperti pasar, terminal, dan sarana olahraga yang memungkinkan menjadi sumber penularan Covid-19. Tujuan kegiatan ini adalah untuk meningkatkan pengetahuan, persepsi, sikap, dan perilaku tokoh masyarakat dalam pencegahan Covid-19 di Desa Haurpanggung. Metode kegiatan adalah analitik kuantitatif dengan jenis metode menggunakan one group pretest and postest tanpa kelompok pembanding. Uji statistik yang digunakan yaitu uji t dependen (paired t test). Populasinya adalah tokoh masyarakat sebagai mitra kuliah kerja nyata mahasiswa Universitas Padjadjaran yang berjumlah 40 orang. Hasil kegiatan menunjukan, sebelum dilakukan edukasi secara daring, nilai pengetahuan terendah sebesar 6 poin dan setelah dilakukan edukasi meningkat menjadi 9,9 poin. Nilai persespsi dari 25 poin meningkat menjadi 33 poin. Sikap meningkat dari 25 menjadi 36 dan perilaku meningkat dari 21 menjadi 27 poin. Hasil tersebut merupakan potensi yang strategis untuk pencegahan Covid-19. Kesimpulan yang dapat diambil adalah terdapat pengaruh edukasi daring tentang pencegahan Covid-19 terhadap peningkatan pengetahuan, persepsi, sikap, dan perilaku tokoh masyarakat di Desa Haurpanggung.
Acquired Long QT Syndrome and Torsades de Pointes after Mitral Valve Replacement Surgery
Authors: Rodríguez-Artuza Carlos , Barajas Héctor , Rivera José , Clavel Emilio , Labarca Mayela
Published: May 2021

Acquired long QT syndrome (aLQTS) can occur in up to one third of patients undergoing cardiac surgery and is often undisclosed. We present a case of a 55-year-old male patient admitted to our center for mitral valve replacement surgery, and, during the postoperative period, a long QT greater than 600 ms was confirmed and in the Holter monitoring Torsade de Pointes (TdP) was evidenced. The patient received appropriate medical treatment and was discharge in stable clinical conditions.
Substantial record of whitecheek monocle bream, Scolopsis vosmeri (Family: Nemipteridae), from Iraqi marine waters
Authors: Jawad Laith A. , Mutlak Falah M. , AL-Faisal Abbas J. , Waryani Baradi
Published: May 2021

Three specimens of whitecheek monocle bream, Scolopsis vosmeri (Bloch) were collected from Iraqi marine waters in the northwest Arabian Gulf. This is a substantial, confirmed record of this species from Iraqi marine waters. Body coloration characterizes this species. The presence of this species was revealed as a result of comprehensive ichthyological investigative work in the area.
How does the ski boot affect human gait and joint loading?
Authors: Lann vel Lace Karol , Błażkiewicz Michalina
Published: May 2021

Study aim: To investigate the effect of wearing ski boots on kinematic and kinetic parameters of lower limbs during gait. Furthermore, loads in lower limb joints were assessed using the musculoskeletal model.

Material and methods: The study examined 10 healthy women with shoe size 40 (EUR). Kinematic and kinetic data of walking in ski boots and barefoot were collected using a Vicon system and Kistler plates. A musculoskeletal model derived from AnyBody Modeling System was used to calculate joint reaction forces.

Results: Wearing ski boots caused the range of motion in the knee joint to be significantly smaller and the hip joint to be significantly larger. Muscle torques were significantly greater in walking in ski boots for the knee and hip joints. Wearing ski boots reduced the reaction forces in the lower limb joints by 18% for the ankle, 16% for the knee, and 39% for the hip.

Conclusions: Ski boot causes changes in the ranges of angles in the lower limb joints and increases muscle torques in the knee and hip joints but it does not increase the load on the joints. Walking in a ski boot is not destructive in terms of forces acting in the lower limb joints.
Sustainable Operational Analysis of the Cultivation of Indonesian Thunnus albacares by Bioeconomic Approach
Authors: Primyastanto Mimit , Lestariadi Rizky Agung , Haris Ade Khadar
Published: May 2021

This study aimed to describe the characteristics and cultivation conditions of Thunnus albacares in Pelabuhan Perikanan Pantai (PPP, shore-port fisheries) of Labuhan Lombok, East Lombok. Data was collected by a simple random sample using a questionnaire for 30 fishing boats. Primary data was collected by interview with respondents and field observation, while secondary data was obtained from records of PPP in Labuhan Lombok, BPS and DKP, East Lombok. Results showed that East Lombok has a high potential for T. albacares cultivation as well as eco-friendly fishery cultivation; this is practiced by local fishermen who commonly use traditional boats sized 4-7 GT complete with fishing utilities, including handline rods and trolling rods. From a biological aspect, there was open access to T. albaceros in 2006, followed by biological overfishing in 2007, and economic overfishing in 2005, 2008, 2009, 2010 and 2011. The maximum sustainable yield (MSY) reached 922,518.18 kg per year (MSY level 3,313 per year). The resource optimization of T. albaceros reached the peak of maximum economic yield (MEY) valued at IDR 24,693,982,361, with fish haul efforts from 2,063 annual trips yielding 791,270.90 kg of tuna per year.
Quercetin Improves the Endocrine Function of Rat Testicular Tissue Under in Vitro Conditions
Authors: Benko Filip , Hrnčiar Patrik , Lukáč Norbert , Kirchner Róbert , Tvrdá Eva
Published: May 2021

Compounds of natural origin are often used for their beneficial effects on the male endocrine system and the synthesis of steroid biomolecules in testicular tissue. One of such compounds is quercetin (QUE), which belongs to the flavonoid family and is found in a wide range of vegetables, fruits and plant products. The purpose of this study is to evaluate the impact of QUE on the endocrine function of rat testicular fragments under in vitro conditions. Testicular fragments from adult Wistar rats (n=9), cultured in the D-MEM medium with different concentrations of QUE (namely 1, 10 and 100 µmol/L) for 24 h at 37°C (5% CO2), were used in the experiment conducted. Following culture, the medium was separated and the levels of cholesterol (CHOL) and male hormones were measured. CHOL values were quantified spectrophotometrically, whereas the concentrations of androstenedione (ANDRO), dehydropeiandrosterone (DHEA) and testosterone (TEST) were quantified using the enzyme-linked immunosorbent assay (ELISA) commercial kit. The results obtained indicate that 10 µmol/L QUE significantly increased (P<0.001; P<0.05) the concentrations of all the steroid biomolecules considered (CHOL, ANDRO, DHEA and TEST) when compared to the control samples. Accordingly, our findings confirm the positive impact of QUE on the endocrine function and steroidogenesis of rat testicular tissue under in vitro conditions.
Creating Maps in R (Case Study: National Park “Fruška Gora”)
Authors: Lakićević Milena
Published: May 2021

This paper aims to present the possibilities for creating maps in the programming language R. Even though R is primarily developed as a statistical program, its application in the area of mapping and spatial statistics is becoming frequent and highly relevant. Many R packages make the mapping process easier and user-friendly, and this paper presents the most commonly used ones: “leaflet”, “ggplot2” and “ggmap”. The selection of the R package depends on the user’s proficiency in R programming but also depends on the visual quality of the map the user wants to gain. Based on the questionnaire conducted in this research, the paper recommends application of the “leaflet” package for the beginners, the “ggplot2” package for medium proficient users, and the “ggmap” package for the most advanced R users. After creating maps in R it is possible to conduct additional analysis related to processing of the spatial data contained within, and this would be a recommendation for future research. In this paper, the mapping process is demonstrated on the case study of the National Park “Fruška gora” in Serbia, and different types of maps are presented.
Attitude of Vegetable Farmers in Galle District in Sri Lanka Towards Good Agricultural Practices (GAP)
Authors: Malkanthi S. H. P. , Thenuwara A.M. , Weerasinghe W A R N
Published: May 2021

Vegetable farmers are facing a number of challenges including price fluctuations, production and marketing problems, low level of income etc. One strategy to overcome these problems is adoption of Good Agricultural Practices (GAP) in vegetable production. However, there is limited information regarding farmers’ awareness of GAP and its applications under the circumstances of farming in the country. Therefore, assessing farmers’ attitude is a timely requirement for directing farmers towards good agricultural practices. Thus, the objectives of the research were to assess the level of awareness of GAP program, relationship between socio-economic factors and awareness of GAP, farmers’ attitudes towards GAP program, factors affecting the willingness to adopt GAP program and the potentials and constraints in implementing GAP program in Galle District. A sample of 100 vegetable farmers in the district was selected through a multi-stage simple random sampling technique. Data were collected from March to July 2018, through a self-administered questionnaire survey and analyzed using descriptive statistics and chi-square test. The results revealed that the majority of vegetable farmers in the district were middle-aged males who had studied up to GCE ordinary level and they received a monthly income of 24000 LKR. Their age, gender, educational level and experience were significantly associated with the level of awareness of GAP program. However, despite their positive attitude towards GAP, most farmers were unwilling to take a risk to adopt GAP due to many issues such as lack of required inputs, capital, required field conditions, information and technical know-how. There are several potentials and also many constraints for implementing GAP in the district. Therefore, providing firstly better theoretical knowledge and then providing the main requirements will motivate more farmers to adopt GAP in their vegetable production procedures. Research studies related to application of GAP by Sri Lankan farmers are still at a lower level. This research thus will be useful for different stakeholders related to adoption of GAP in Sri Lanka.
Geoinformatics Technologies for Preservation of Cultural Heritage, Case Study, Rákóczi-Bánffy Castle, Urmeniș, Bistriţa Năsăud County, Romania
Authors: Rădulescu V.M. , Rădulescu G.M.T. , Naș Sanda , Rădulescu A.T. , Bondrea M. , Rădulescu Corina M.
Published: May 2021

The paper presents an application of the methodology used in the paper “Synthetic analysis of geoinformatics technologies for cultural heritage conservation, methodological approach”. The creation of the 3D model of the Rákóczi-Bánffy Castle in Urmeniș, Bistrița Năsăud County, was done by applying and integrating Terrestrial Laser Scanning (TLS) technologies and aerial photogrammetry performed with an Unmanned Aerial Vehicle (UAV). Agisoft Photoscan was used to compare the results and then they were compared with the images scanned using CloudCompare software. Thus, following the performance, with the help of the mentioned software, of a series of processing of the point cloud obtained, through the two imaging technologies, the error between the points belonging to the point cloud taken with UAV and the one taken with Laser Scanner was between 1 and 15 mm, the margin of error being acceptable for monuments without complex architectural details, so that the point cloud resulting from UAVs can be used successfully in this activity. The aim of the paper is to elaborate a geomatic methodology with an optimized cost-quality ratio, later replicable in the analysis of the current state of other constructions of the same type, knowing that over 600 castles in Transylvania alone are in a similar state, and such cases can be found in other Central European states as well.
Dynamism of Landscape Transformation in Ibiono-Ibom, Akwa-Ibom State, Nigeria
Authors: Isaac Orimoogunje Oluwagbenga O. , Olufemi Adeleke Benjamin , Emmanuel Dada , Adekunle Shote Adebola , Nene Eudoxie-Okafor Aniefiok , Isioma Nwayor Jessica
Published: May 2021

Studies have shown that information on landscape transformation is an important benchmark data set because of its value as an environmental change indicator. Therefore, dynamism of landscape transformation over a 34-year period are analysed for a case study in Ibiono-Ibom, Akwa-Ibom State, Nigeria. The study adopted a mixed method consisting of remote sensing and GIS-based analysis, and semi-structured interviews covering 400 households while factors contributing to landscape structures and changes are studied. The results point out three main driving factors responsible for the landscape transformation in the study area: agricultural practices which lead to intensification of forest resources, riparian vegetation, vegetated wetlands and non-vegetated wetlands; urbanization which modifies the structure and morphology of the landscape, and finally, population growth directly related to massive infrastructural development which encroached on all other land spaces. GIS-based analysis of remotely-sensed data showed that built-up area had increased by 7535.2 ha between 1986 and 2020; shrub and arable land by 1343.9 ha and light forest decreased by 4998.3 ha. While bare-land reduced by 1522.1 ha; vegetated wetland reduced by 1092 ha; water body coverage reduced by 168 ha and non-vegetated wetland size also reduced by 2029.4 ha. Analysis of household survey results revealed that the perceptions of respondents validate the observed patterns during the remotely-sensed data analysis phase of the research, with 54 % (n=400) of respondents reporting a decline in agricultural land use, and 19.3 % (n=400) observing a decline in forest areas in the study area. Furthermore, agricultural intensification, urban development, timber exploitation, firewood collection and increase in settlements were identified as the proximate drivers of these observed landscape transformation dynamics in the study area. The study concluded that the variation in landscape transformation of the study area are clear indication of the extent of biodiversity loss and ecosystem degradation in the study area.
Does Experimental Non-Reclaimed Sites Differ from Technically Reclaimed Areas in the Risk of Artificial Bird Nest Predation?
Authors: Novák Jakub , Hendrychová Markéta
Published: May 2021

Areas left to natural development have been found to be sites with higher diversity and conservation value of local communities, including bird communities, compared to artificial reclamation of post-industrial areas. Most of the studies conducted so far have focused primarily on bird communities of post-mining areas, in terms of the diversity and richness of species. Our study dealt with bird nest predation on specific case of two experimental sites (20 and 32 ha) with more than a 20-year history of primary spontaneous succession established within the technical reclamation of the Radovesická spoil heap (approx. 1,200 ha, North Bohemia, Czech Republic). In the spring of 2018, we conducted a predation experiment using artificial nests (ground and elevated), installed within both succession areas and beyond, in the adjacent artificially reclaimed areas. We monitored the way of restoration and the distance of the nest placement from the succession-reclamation sites edge. The rate of predation was very high: 92.5 % in reclaimed area and 89.4 % in spontaneous successions. None of the observed factors analysed in the generalised linear model (GLM) have conclusively explained the risk of predation. The two experimental succession sites did not differ from the surrounding reclaimed sites in terms of the risk of predation, nor did they significantly influence predation risk on reclaimed sites. We believe that both relatively small and mutually isolated areas do not provide enough of an inner environment without or with at least a limited effect of predation pressure coming from adjacent reclaimed areas.
The Effect of Reynoutria × Bohemica on the Condition of Capreolus Capreolus and Cervus Elaphus
Authors: Ernst Martin , Maděra Petr , Frantík Tomáš , Novák Jan , Vencl Štěpán
Published: May 2021

The objective of the work is to evaluate the effects of a granulated feeding mixture enriched with knotweed (Reynoutria × bohemica) on roe deer (Capreolus capreolus) bred at a closed farm and red deer (Cervus elaphus) bred at a farm. Based on both biochemical and haematological blood analysis, the knotweed is expected to have an influence on the microbiome in the digestive system as well as allowing better utilisation of fodder and lower manifestation of pathogenic organisms. The results are of practical use mainly on farms and in hobby breeding but also in deer parks. Furthermore, the results may be used for feeding deer in open hunting grounds.
Practical Issues Regarding International Underppinnings of Tax Legislation Under the Auspices of Law No. 296/2020
Authors: Dumiter Florin Cornel , Jimon Ștefania Amalia
Published: May 2021

In this article, it will be analyzed, from the perspective of doctrine and jurisprudence, the implications of some international aspects of tax legislation, under the auspices of the latest changes in the field of taxation made by Romania. For this purpose, it will be analyzed the implications of the new fiscal provisions regarding the international aspects from the perspective of Law no. 296/2020. In this sense, it will be focused upon certain issues such as international double taxation, transfer prices, affiliated businesses and corporate tax. Also, the case presented in the jurisprudence section enriched in the second part of the article comes to support the framework of the future application of the new provisions regarding certain fiscal aspects with elements of foreignness in Romania. The results of the research subsumed in this article highlight the fact that the tax legislation in Romania has had a significant improvement, especially in terms of international aspects of financial and tax law. In conclusion, both the analysis of the evolution of tax legislation and the case law presented show that there are significant improvements at a national level, both in terms of the quality of the enactment of a tax law and the way in which the provisions of the law are implemented in practice.
Subliminal Advertising: Ethical and Legal Problems of Existence in Ukraine
Authors: Kyrylenko Mariia
Published: May 2021

In the present article, the issue of identification of sophisticated and problematic aspects of the regulation of subliminal advertising in the national legislation of Ukraine and perspectives for the improvement of the legal regulation of subliminal advertising is considered. It is determined that legislative and normative regulation of public relations that arise in the process of defining the concept of subliminal advertising and the problems of such legislative regulation are urgent questions in the current society. Given that subliminal advertising affects subconsciousness and manipulates human behavior, it harms not only consumers of advertising, as it misleads, disorients, has a subliminal effect, but also deprives media outlets of adequate payment for fair advertising. Besides, hidden advertising also harms society by ignoring the laws, requirements of journalistic ethics and hence – provides demoralization. That is why there is a necessity to analyze ambiguous aspects of subliminal advertising and justify the need to improve the possibilities of its legal limitations and control.
Development of the Magistrate’s Intime Conviction in the Context of Non-Verbal Communication
Authors: Iovan Marţian
Published: May 2021

The author of this paper tackles the concept of intimate conviction of the magistrate (judge, prosecutor) and relevant aspects of the etiology and practical importance of its content, as a subjective basis for establishing judicial questioning tactics that help the magistrate in his/her decision-making. By approaching the process of intimate conviction development as part of an interpersonal communication system, the author analyses the contribution of interpreting nonverbal, extra-semantic clues given by the person being questioned and by all participants in courtroom debates, to the detection of feigned behaviors and the subsequent adjustment of questioning, paving the way for the development of an intimate conviction. Consequently, improving hearing and questioning practices for the accused, the investigated, and witnesses involves professional control and self-control in terms of eye contact, facial expression, gestures, stance, paralanguage, touching, proximity, and dress, in order to masterfully achieve specific goals in delivering justice.
Changes in Brand-Related Consumer Loyalty in the Current Pandemic Context
Authors: Duralia Oana
Published: May 2021

The current medical crisis and, implicitly, the economic one, generated by the Covid-19 pandemic have brought increased attention to the issue of brand-related consumer loyalty, as loyal consumers are the safest and most stable source of profit in the current economic and social context. It is well-known that there is no equality between the notions of consumer satisfaction and loyalty. The two notions are not synonymous, as consumer satisfaction is only a relative, but not sufficient condition to obtain consumer loyalty. This paper aims to take a systemic approach in discussing the issue of brand-related consumer loyalty, starting from the inputs, respectively the favorable factors that lead to consumer attraction, retention and, finally, to the desired output, respectively to their loyalty. The whole approach will be supported by the use of secondary data sources that will be used in order to pinpoint some essential aspects of the changes that took place in 2020 in what regards the consumer’s attachment to the brand.