bluuebunny/crossref_metadata_2025 huggingface dataset:
Hubungan Anemia dengan Remisi Komplit Kemoterapi induksi pada Pasien Leukemia Mieloblastik Akut Dewasa di RSUP Dr. M. Djamil Padang
Authors: Salsabila Zahra , Afriant Rudy , Rofinda Zelly Dia , Elvira Dwitya , Yaswir Rismawati , Izzah Amirah Zatil
Published: March 2024

Latar Belakang: leukemia mieloblastik akut merupakan salah satu keganasan darah yang terjadi akibat gangguan proses pertumbuhan sel mieloid, yang menyebabkan terjadinya penumpukan sel blast di sumsum tulang, dan menekan pembentukan sel darah lain yang menyebabkan anemia.  Pengobatan yang diberikan pada penderita LMA adalah kemoterapi. Kondisi anemia dapat menyebabkan hipoksia di jaringan, yang dapat mengakibatkan berkurang nya efektivitas kemoterapi.  
Objektif: Tujuan dari penelitian ini adalah untuk menganalisis hubungan antara derajat anemia dengan tercapainya remisi komplit pada pasien LMA yang di kemoterapi induksi.
Metode: Penelitian ini dilakukan dengan menggunakan desain cross sectional dengan pendekatan observasional analitik retrospektif. Sampel pada penelitian ini berjumlah 15 sampel yang diambil dari data rekam medik. Analisis univariate dilakukan untuk mendeskripsi frekuensi variable dan analisis bivariate dengan uji statistic fisher exact test.
Hasil: Hasil yang didapat dari penelitian ini adalah pasien LMA banyak yang berusia >40 tahun, berjenis kelamin perempuan, dengan klasifikasi LMA M4, keluhan utama lemah letih, derajat anemia ringan dan berhasil remisi komplit yang lebih banyak. Hasil uji statistik memperlihatkan tidak adanya hubungan derajat anemia dengan tercapainya remisi komplit pada pasien. Hasil analisi LMA dengan nilai p=1,000.
Kesimpulan: kesimpulan yang didapatkan adalah tidak adanya hubungan antara derajat anemia dengan tercapainya remisi komplit pada pasien leukemia mieloblastik akut dewasa yang menjalani kemoterapi induksi di RSUP Dr. M Djamil Padang.
Gambaran Kelainan Refraksi di Poliklinik Mata RSUP Dr. M. Djamil Padang Tahun 2021
Authors: Dzulkifli Dzulkifli , Hidayat Muhammad , Liza Rini Gusya , Vitresia Havriza , Adrial Adrial , Fadrian Fadrian
Published: March 2024

Latar belakang: Kelainan refraksi merupakan tidak tepatnya cahaya jatuh di retina yang diakibatkan panjang aksial mata serta kekuatan optik yang terganggu. Ametropia adalah kondisi cahaya tidak dapat difokuskan di retina tanpa bantuan akomodasi karena adanya kelainan refraksi pada mata. Terdapat tiga jenis kelainan refraksi, yaitu miopia, hipermetropia, serta astigmatisme.
Objektif: Tujuan penelitian ini adalah untuk mengetahui gambaran kelainan refraksi di Poli Mata RSUP Dr. M. Djamil Padang.
Metode: Penelitian ini merupakan penelitian deskriptif observasional melalui studi kasus dengan mengumpulkan data rekam medis pasien kelainan refraksi di Poliklinik Mata RSUP Dr. M. Djamil Padang periode 1 Januari 2021 – 31 Desember 2021 dengan mata yang didiagnosis kelainan refraksi yang memenuhi kriteria inklusi dan ekslusi sebanyak 110 pasien. Seluruh variabel dianalisis dengan analisis univariat.
Hasil: Hasil penelitian menunjukkan 85 pasien didiagnosis astigmatisme, dengan 50 pasien didiagnosis miopia, serta 8 pasien didiagnosis hipermetropia. Pasien kelainan refraksi dengan kelompok usia terbanyak adalah pada rentang 10-19 tahun (31.82%) dengan mayoritas perempuan (67.27%). Gejala klinis terbanyak adalah pandangan kabur (100%). Berdasarkan tingkatannya pasien miopia terbanyak adalah miopia tinggi (70.73%), hipermetropia terbanyak adalah hipermetropia rendah (76.92%), lalu astigmatisme miopia kompositus merupakan jenis astigmatisme terbanyak (83.01%). Visus pasien kelainan refraksi sebelum dan sesudah dikoreksi terbanyak adalah kelompok mild – no visual impairment (39.54%) & (94.09%).
Kesimpulan: Gambaran dari pasien kelainan refraksi pada penelitian ini rentang usia 10-19 tahun merupakan kelompok usia terbanyak serta perempuan mengalami kelainan refraksi lebih banyak dari laki-laki. Dengan miopia derajat tinggi merupakan miopia terbanyak. Hipermetropia derajat rendah merupakan yang terbanyak. Serta astigmatisme miopia kompositus merupakan kelompok astigmatisme terbanyak. Keluhan umum terbanyak adalah pandangan kabur. Kategori visus terbanyak sebelum dan sesudah dikoreksi adalah kategori mild – no visual impairment.
Kata kunci:  miopia, hipermetropia, astigmatisme
O sistema constitucional de seguridade social e o princípio da subsidiariedade
Authors: Moimaz Marques Carlos Gustavo , Pierdoná Zélia Luiza
Published: March 2024

O presente artigo analisa como o princípio constitucional da subsidiariedade reforça o principal instrumento de proteção social estabelecido no artigo 194 da Constituição Federal, denominado seguridade social. Partindo das premissas internacionais que desenharam a teia de proteção social denominada “seguridade social”, destaca-se o princípio da subsidiariedade como diretriz estruturante para garantir a compreensão da seguridade social como sistema e sua própria operacionalidade. A partir dessas premissas e se valendo da experiência brasileira obtida nos mais de trinta anos do sistema de seguridade social, trazido pela Constituição Federal de 1988, objetiva-se apontar o desapego dos Poderes Constituídos brasileiros com o vetor principiológico da subsidiariedade na seguridade social brasileira, minando em grande parte as próprias premissas que norteiam a consagrada ideia de “seguridade social”.
GUGATAN ACTIO PAULIANA TERHADAP DIREKSI DAN KOMISARIS ATAS PENOLAKAN PENGEMBALIAN DIVIDEN INTERIM PEMEGANG SAHAM PERSEROAN TERBATAS
Authors: Yusuf Chandra
Published: March 2024

Distribution of interim dividends distributed before the end of the financial year by the Director with the approval of the Commissioner. This distribution can be made if the company's finances are in a profitable condition based on the year-end audit carried out by a Public Accountant. Companies that experience losses in their reports at the end of the year, shareholders are obliged to return interim dividends based on Law Number: 40 of 2007 concerning Limited Liability Companies. Likewise, companies experiencing bankruptcy based on Law Number: 37 of 2004 concerning Bankruptcy and Postponement of Debt Payment Obligations. The curator in bankruptcy based on Auctio Pauliana with other claims can request the return of the company's interim dividends in the Commercial Court. However, the Curator can only ask for responsibility for the return of interim dividends to the Director and Commissioner jointly and severally. The obligation of the Directors, whose authority has been taken over by the Curator, is to sue the shareholders in the District Court based on Law Number: 40 of 2007 concerning Limited Liability Companies. The problem is, cases in District Court are complicated cases, not simple cases. This research uses normative juridical methods. In the discussion, the Director whose authority has been taken over by the Curator, if the shareholders reject the return of the interim dividend, will file a lawsuit in the District Court. However, a case at the District Court will take a long time, therefore the dividend return case must be submitted to the Commercial Court. In conclusion, to make it easier for the Director to file a lawsuit for the return of interim shareholder dividends in the Commercial Court, the Curator will provide a power of attorney and the case for the return of interim dividends will be made simple.
Integrated MSW management system in the Russian Federation: problems of interpretation and formation
Authors: Molokov Mihail Alekseevich
Published: March 2024

The object of the study is the formation of an integrated MSW management system within the framework of the national project "Ecology" and the federal project "Integrated Solid Municipal Waste management System". The subject of the study is organizational, methodological, legal, financial, economic, industrial and technological problems that make it difficult at the federal and regional levels to achieve the annual and final planned indicators of these projects in 2024. The purpose of the work is a general description of the integrated MSW management system being created, as well as to identify the main problems of its formation in the new financial and economic environment reality. The author considers the planned target indicators of the federal project and their correlation with the indicators achieved in 2019-2022. Special attention is paid to the three-fold decrease in the initial planned indicator for recycling, which occurred due to insufficient development of the MSW recycling infrastructure, and the threat of non-fulfillment of the utilization indicator in 2024, which persists even after that. The methodological basis of research is an integrated approach that allowed the use of methods of systematic, comparative, factorial and economic-statistical analysis, content analysis, and also synthesis. The scientific novelty of the work lies in the disclosure of an integrated system as a set of methods for handling MSW, located among themselves in a certain hierarchy of applications, the last of which is waste disposal, and the smaller its scale and the damage caused to the environment, the greater the level of consistency the system demonstrates. Neutralization and energy utilization do not fully solve the problem, since they leave a lot of harmful combustion products. Recycling is much more environmentally friendly, the degree of development of which should be considered as the second important criterion for the development of an integrated waste management system. The reduction by the curators of the MSW management reform of the initially stated recycling targets for 2024 by three times is actually an official recognition of the global underdevelopment of the domestic recycling and processing industry and the lack of real state participation in its formation and development.
Immersion cooling technology development status of data center
Authors: Zhou Kun , Yu Xiaolin , Xie Baogang , Xie Hongxi , Fu Wei
Published: March 2024

With the continuous development of data centers and information technology equipment, data center energy consumption continues to increase, China’s data center energy consumption has accounted for 4% of the power consumption of society as a whole, while the data center cooling system accounts for 30–50% of the data center energy consumption. At the same time, with the development of new high-energy chips, the traditional cooling methods have been unable to meet the requirements of IT equipment cooling, so how to reduce the energy consumption of data centers, especially the cooling system energy consumption, and to meet the cooling requirements of data centers with high heat flux density is becoming the focus of research in the field of data centers. In order to solve the data center cooling system of high energy consumption and high heat flow density needs, immersion cooling technology came into being, this paper is mainly on the data center immersion cooling technology research, and the use of the current situation is introduced and explained, compared to the single-phase immersion cooling technology and two-phase immersion cooling technology cooling principle, the current state of development and use of the prospects for elaboration, while the data center immersion cooling system waste heat utilization is explored, providing readers with a wide range of data center cooling system. At the same time, the utilization of waste heat in the data center immersion cooling system is discussed, providing readers with extensive and detailed background knowledge of data center immersion cooling technology.
Pulmonary function assessments and clinical correlates in children with sickle cell disease in Cape Town, South Africa
Authors: Owusu Sandra Kwarteng , Mapani Muntanga Kampengele , Visagie Ane , Marozva Nicola , Yassin Aamir , Vanker Aneesa , Hendricks Marc , Davidson Alan , Ansong Daniel , Zar Heather , Gray Diane
Published: March 2024

Objectives:

Among children with sickle cell disease (SCD) in Africa, there are varied reports on pulmonary function assessments. Restrictive pulmonary function is common in children with SCD in Africa; however, reports from Africa are few. We aimed to describe pulmonary function and its clinical correlates in children with SCD in Cape Town, South Africa.

Materials and Methods:

A prospective cross-sectional study was carried out over seven months from October 2018 to April 2019 in children 6–16 years with SCD. Children with hemoglobin (Hb) genotypes, homozygous for the BS globin mutation, and sickle-beta0-thalassemia Hb were included in the study. Children were excluded if they had acute complications. Medical record review clinical, laboratory, and pulmonary function assessments were done. Data were entered into Excel and exported to Stata Version 16.0 statistical software for analysis.

Results:

A total of 25 participants were recruited, mean (standard deviation) age of 10 ± (3.0) years. Thirteen (53%) children were under ten years and 15 (60%) were male. The median/interquartile range age at diagnosis was 1.7 [0.8–3.0] years. SCD-related complications were common. A review of the medical records showed a third of the patients (32%) had at least one previous episode of acute chest syndrome, 20 (80%) had a history of vaso-occlusive crisis, and 15 (76%) had required at least one blood transfusion. Spirometry was performed on 19 (76%) of the participants 9 (47%) had abnormal lung function. The most common spirometry abnormality was a restrictive pattern (forced vital capacity (FVC) < lower limit of normal (LLN)). No participant had a positive bronchodilator response. Older age was associated with a decrease in forced expiratory volume in the first second (FEV1) Z-score (−0.16, 95% confidence interval [CI] −0.31, −0.01; P = 0.04). Children on hydroxyurea similarly had reduced FEV1 Z-score (−1.5, 95%CI −2.88, −0.12; P = 0.04) and reduced FVC Z-score (−2.21, 95%CI −3.64, −0.79; P < 0.001).

Conclusion:

Lung function abnormalities were common among children with SCD, with restrictive abnormality predominating. Asthma and obstructive airway abnormalities were uncommon in children with SCD in South Africa.
Portrait of Poverty in Palu and Paku, Usaha Samad, and Si Sapar by Utuy Tatang Sontani: Literary Sociology
Authors: Wulanjari Raras Cynantia
Published: March 2024

This research analyzes the portait of poverty depicted in three short stories of Utuy Tatang Sontani: “Palu and Paku, “Usaha Samad”, and “Si Sapar”. The focus of this research is social conflict, injustice, and the interaction between the characters in the context of poverty. The short story “Palu and Paku” tells about the life of a pedicab driver who faces a challenge to maintain his dignity in the midst of difficult economic conditions. “Samad’s Effort” tells the story of the persistence and struggle of a street vendor trying to escape poverty. And in “Si Sapar”, Utuy talks about the poverty of street children and how poverty can affect a person’s life from an early age. This research deeply discusses the depiction of poverty in Utuy Tatang Sontani’s literary works and how literature functions as a social reflection that reflects social reality. The findings in this study are expected to contribute to the development of literary sociology and raise awareness of social issues in literature and society in general, especially regarding poverty.
Excelzyme: A Swiss University-Industry Collaboration for Accelerated Biocatalyst Development
Authors: Honda Malca Sumire , Stockinger Peter , Duss Nadine , Milbredt Daniela , Iding Hans , Buller Rebecca
Published: March 2024

Excelzyme, an enzyme engineering platform located at the Zurich University of Applied Sciences, is dedicated to accelerating the development of tailored biocatalysts for large-scale industrial applications. Leveraging automation and advanced computational techniques, including machine learning, efficient biocatalysts can be generated in short timeframes. Toward this goal, Excelzyme systematically selects suitable protein scaffolds as the foundation for constructing complex enzyme libraries, thereby enhancing sequence and structural biocatalyst diversity. Here, we describe applied workflows and technologies as well as an industrial case study that exemplifies the successful application of the workflow.
The Content Analysis of Grammar Activities in 'Wider World 2' Student’s Book by Pearson for Grade Seven Students
Authors: Juniar Rima
Published: March 2024

The objective of this study is to use Bloom's revised taxonomy to analyze the context of the grammar activities in Wider World 2 Student’s Book. To achieve the research goal, a content analysis was performed. The researcher analyzed the textbook based on Bloom's revised taxonomy. According to the data, the textbook has dominant grammar activities, particularly on the cognitive process of "understand" and "remember" with 47% and 32% out of 189 grammar activities. Moreover, the data shows that the grammar activities in the textbook have an uneven distribution of higher and lower cognitive processes. There is a vast lower thinking skills percentage since most grammar activities focus on the "understand" aspect. While the second dominant aspect is "remember" which includes lower thinking skills. Therefore, Wider World 2 Students’ Book highlights Bloom’s revised taxonomy’s lower cognitive thinking process, represented by the “understand” and “remember” thinking processes.
An Analysis of Project Based Learning Application in Curriculum 2013
Authors: Wisudawaty Umi
Published: March 2024

This paper describes how project-based learning application in the classroom towards Curriculum 2013. A brief analysis on how project-based learning as a learning method especially in teaching English for senior high school students in curriculum 2013 will be applied in this paper. In addition, Curriculum 2013 requires teachers to apply various scientific approaches to engage students' activeness and maximize their ability in acquiring the materials. As one of them is project-based learning. This paper applied qualitative descriptive method, which analyzes how the project-based learning will affect students' performance in learning English on senior high school students in 2013 curriculum. The writer analyzes several research that has been applied in the classroom towards the project-based learning application. The result shows that project-based learning improved and significantly influenced students' speaking ability, reading comprehension, writing ability, classroom activity, and critical thinking.
Prognostic Factors for Early-Stage Endometrial Cancer Management in Fertile Patients
Authors:   Professor Obstetrics and Gynaecology, University of Nicosia, Medical School and Aretaeio Hospital, Cyprus MBBS Student, University of Nicosia, Class of 2025, Cyprus Foundation Year Doctor, Antrim Area Hospital, Antrim, Northern Ireland, Tanos Vasilios , Zervides Zoe ,   Professor Obstetrics and Gynaecology, University of Nicosia, Medical School and Aretaeio Hospital, Cyprus MBBS Student, University of Nicosia, Class of 2025, Cyprus Foundation Year Doctor, Antrim Area Hospital, Antrim, Northern Ireland, Tanos Panayiotis ,   Professor Obstetrics and Gynaecology, University of Nicosia, Medical School and Aretaeio Hospital, Cyprus MBBS Student, University of Nicosia, Class of 2025, Cyprus Foundation Year Doctor, Antrim Area Hospital, Antrim, Northern Ireland
Published: March 2024

Introduction: Early-Stage Endometrial Cancer (ES-EC) presents a treatment challenge for women who would like to preserve their genital organs and complete their family planning. Delayed first pregnancy and aging of women in combination with high-definition sonography and cancer awareness is expected to increase the incidence of young women with ES-EC demanding Fertility Sparring Surgery (FSS). Methods: A thorough literature search was conducted using Medline (OVID), Embase, and Cochrane Library electronic databases in order to identify eligible studies published up to November 2021. Results: Age is an imperative determinator for FSS in ES-EC, since fertility potential is compromised with age and oocytes carrying higher risk of fragmented DNA. Favourable prognostic factors to FSS include, age younger than 35 years old, absent genetic predisposition to EC, fertile females with normospermic partners, negative histology for cancer cells after hysteroscopic biopsies and progesterone treatment, normal adnexal findings in Trans Vaginal Ultrasound (TVU), absent myometrial carcinomatous invasion in Magnetic Resonance Imaging (MRI) and absence of lympho-vascular involvement in Computerised Tomography Scan. Careful selection of patients based on favourable prognostic factors diminishes the risk of recurrence and allows for the opportunity of reproductive organs preservation until family planning is achieved in a reasonable time frame. Additionally, our review points out the need of hysteroscopic guidance in endometrial sampling for primary EC diagnosis as well as for the endometrial surveillance every 3-6 months follow-ups until pregnancy. Conclusion: After FSS decision, a strict time frame of one year to achieve pregnancy is essential in order to secure patient’s safety and to reduce the risk of early recurrency in EC.For both endometrial and ovarian cancer, prevention Hysterectomy and Bilateral Salpingo-oophorectomy should preferably be performed by the completion of child bearing age and before the age of 40 years. It is vital that the advantages and risks of FSS must be discussed openly, including the risk of undetectable by imaging occult gynecological cancer which can compromise life expectancy.
Spontaneous Heterotopic Pregnancy: As One of the Most Challenging Emergency Cases in Obstetrics
Authors:   Department of Obstetrics and Gynecology, Damascus University, Damascus, Syria, Katti Fatima , Jawabrah Ebraheem ,   Department of Obstetrics and Gynecology, Damascus University, Damascus, Syria, Barghash Huda ,   Department of Obstetrics and Gynecology, Damascus University, Damascus, Syria, Abbas Katti Mohammad ,   Faculty of Medicine, Damascus University, Damascus, Syria, Abbassi Haitham ,   Head of Department of Obstretrics and Gynecology, Damscus University, Damascus, Syria
Published: March 2024

Spontaneous Heterotopic Pregnancy “SHP”: is defined as the presence of multiple gestations, in which, intrauterine and extrauterine pregnancy occur simultaneously, it is a life-threatening condition that requires immediate and accurate diagnosis and treatment. Here, we present a case of a 38-year-old pregnant female who conceived spontaneously, at her sixth week of gestation, was presented to the emergency department with acute pain in lower abdomen and minimal vaginal bleeding, she underwent previous falsely reassuring ultrasound imaging for two times and her symptoms were ignored until the diagnosis was finally made by us. Pelvic ultrasound showed evidence of an IUP and a left adnexal mass, raising suspicion for a heterotopic pregnancy. An urgent exploratory laparotomy and a left salpingectomy were performed, postoperative, the patient recovered well but she had an early pregnancy loss at 8 weeks of gestation. Clinicians should keep in mind that confirmation of an Intrauterine Pregnancy (IUP) should not preclude the existence of a heterotopic pregnancy.
Perimenopause Pituitary Hyperplasia with Headache
Authors:   Department of Endocrinology, Government Medical College, Srinagar, India, Alam Md Ejaz , Sharma Pooran ,   Department of Endocrinology, Government Medical College, Srinagar, India, Wani Shazia ,   Department of Endocrinology, Government Medical College, Srinagar, India, Mir Shahnawaz ,   Department of Endocrinology, Government Medical College, Srinagar, India
Published: March 2024

A 50 year-old female presented to the outpatient clinic with one year- history of headache, which was dull frontal mild to moderate in intensity didt not cause any impairment of routine activities. Patient complains of sever menaupsal symptoms. She denied any visual changes, nausea, vomiting, or other neurological symptoms. The patient had no significant past medical or surgical history and was not taking any medications. On examination, the patient was alert and oriented with normal vital signs. Cranial nerve examination was unremarkable, and there were no focal neurological deficits. The rest of the physical examination was within normal limits. Magnetic Resonance Imaging (MRI) of the brain revealed pituitary hyperplasia, with a size of 1.5 cm in the largest dimension (Figure 1). The optic chiasm was normal, and there was no evidence of a mass effect (Figure 2).
Hydroxychloroquine and Azithromycin Molecular Action against SARS-CoV-2 Viral Protein: A Molecular Dynamic Study
Authors:   Nanomedicine Lab EA4662, University of Franche-Comté, France, F Picaud , G Herlem ,   Nanomedicine Lab EA4662, University of Franche-Comté, France
Published: March 2024

For the past few months, the world has gone through hell with the emergence of the SARS-CoV-2 virus and the resulting pandemic. Faced with this disease, various therapeutic strategies have been developed to understand how to eradicate this virus. Here we present a molecular dynamics simulation study on the effect of a dual therapy (hydroxychloroquine and azithromycin) on the open and closed forms of a viral protein. We show in particular that hydroxychloroquine has no significant interaction with the viral receptor-binding domain RBD when it interacts with its host receptor. However, this molecule can, in the closed form of the virus, block the movement of these receptors and thus prevent the attachment of the virus to the host cell. The azithromycin molecule interacts very well with the open receptor but can also be inserted into the S2 domain of the protein. It therefore presents two potential mechanisms of action against the virus, mainly on the closed state of the viral protein.
Biosynthesis of Selected Nanoparticles for Biomedical Applications
Authors:   Institute of Physics, Nuclear Physics Department, University of Sao Paulo, Sao Paulo, Brazil, Ramirez-Perez Javier Christian
Published: March 2024

Nanoparticles (NPs) are materials with a size scale of 100 nm or less. They are produced using a combination of chemical and physical techniques, and frequently include the use of hazardous substances. These hazardous substances are difficult to remove from nanoparticle surfaces, making them bioincompatible and limiting their application as biomedical nanoparticles. Nanoparticles can currently be synthesized biologically using methods based on green chemistry. The fusion of nanotechnology and biology has given rise to a new field called nanobiotechnology, which aims to harness biological entities such as actinomycetes, algae, bacteria, fungi, viruses, yeast, and plants in a number of physicochemical, biochemical, and biophysical processes. Plant extracts have been used in biological applications because they are a rich source of phytomolecules and because their capping and reducing capabilities have been used in the production of metal and metal oxide NPs. The biosynthesized NPs have not only been examined for their antibacterial, antifungal, antioxidant, anticancer, and biocompatibility properties but also for their morphology using a number of analytical techniques. This approach, which is affordable and environmentally friendly, could substitute traditional chemical and physical methods for biomedical applications.
Hoffa’s Fracture Case Report
Authors:   Department of Orthopedic A Traumatological Surgery, Mohamed V Military Hospital, Rabat-Morocco, Rabah Abdelhay
Published: March 2024

Unicondylar fractures of the distal third of the femur in the coronal plane are known as Hoffa’s fractures, they are rare and very rare. Few cases have been reported of this type of fracture, by definition they are unstable fractures and therefore require surgical treatment. The mechanism of trauma in this type of fracture is direct with the knee in flexion. Often they can go unnoticed in the Anteroposterior (AP) X-ray projection, which is why it is important to assess the lateral projection. When they are suspected or highlighted, it is necessary to pass a Computed Tomography (CT) in order to clearly define its surgical resolution, since the approach and method of fixation are controversial. Although today the availability and characteristics of different types of implants have increased, there is no consensus in the literature mainly due to the lack of expertise in these rare cases.
End Stage Hoffa’s Disease Presented as a Giant Osteochondroma: Case Report and Literature Review
Authors:   Department of Orthopedic Surgery and Traumatology, Military Hospital Mohammed V, Rabat, Morocco, Kamal El Mokhtari
Published: March 2024

Introduction: Hoffa’s disease appears to be an under-recognized ailment according to an extensive comprehensive literature assessment. Predisposing factors in sports training include torsion and hyperextexion at the knee should be taken into consideration when evaluating patients with chronic knee pain. We present the case of a young soldier suffering from left knee pain as a result of Hoffa’s disease Case report: A 29-year-old male patient admitted to orthopedic department to assess an anterior mechanical pain on the left knee. He reported that he had a sport accident with notion of hyperextension and anterior direct trauma to the left knee. On physical examination we found a painful mass that seems located under the patellar tendon, passive flexion of the left knee triggered a sharp pain from 100°. On X ray we found bone-like mass located behind the silhouette of the patellar tendon without attachment to the bones of the leg. MRI identified a 4.2 osseous tumor with no attachment to the patellar tendon. A surgical excision was preformed Conclusion: Hoffa disease is relatively a rare illness, its physiopathology is not yet completely clear. But many cases have been reported in literature. Its clinical presentation is not very specific, and its surgical excision which remains unavoidable, guarantees satisfying clinical and functional results. However, it remains to be determined whether it is a definitive solution in the context of “Hoffa’s disease”.
Anterior Dislocation of the Elbow Associated with an Olecranon Fracture: Exceptional Dislocation in Children
Authors:   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V. Rabat, Morocco, R Badaoui , A Rachdi ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V. Rabat, Morocco, M Boussaidan ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V. Rabat, Morocco, Y Benyass ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V. Rabat, Morocco, J Boukhriss ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V. Rabat, Morocco, D Benchaba ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V. Rabat, Morocco, B Chafry ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V. Rabat, Morocco
Published: March 2024

This is a 7-year-old child, victim of a fall a year ago, with landing on the right elbow in flexion. Clinical examination revealed a deformity of the elbow without a skin opening or vasculonerve lesions. X-rays of the elbow face and profile revealed an anterior dislocation of the elbow with fracture of the olecranon.
Late Stage Hoffa Disease
Authors:   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V Rabat, Morocco, R Badaoui , A Rabah ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V Rabat, Morocco, A Rachdi ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V Rabat, Morocco, M Boussaidan ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V Rabat, Morocco, Y Benyass ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V Rabat, Morocco, J Boukhriss ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V Rabat, Morocco, D Benchaba ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V Rabat, Morocco, B Chafry ,   Department of Traumatologie and Orthopedic II, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V Rabat, Morocco
Published: March 2024

A 50-year-old man consulted in March 2019 for left anterior gonalgia that had been evolving for several years. During the interrogation, a notion of old trauma was found. On clinical examination, an anterolateral mass was palpated, the patient had active and passive limitation of knee flexion and extension movements. A standard radiological assessment revealed opacity in the infrapatellar adipose body. MRI showed ossification of the subpatellar fat as well as infiltration of the latter.