bluuebunny/crossref_metadata_2025 huggingface dataset:
Exposure to Bisphenol A Substitutes, Bisphenol S and Bisphenol F, and Its Association with Developing Obesity and Diabetes Mellitus: A Narrative Review
Authors: Alharbi Hend F. , Algonaiman Raya , Alduwayghiri Rana , Aljutaily Thamer , Algheshairy Reham M. , Almutairi Abdulkarim S. , Alharbi Razan M. , Alfurayh Leena A. , Alshahwan Amjad A. , Alsadun Amjad F. , Barakat Hassan
Published: November 2022

Bisphenol A, a well-known endocrine-disrupting chemical, has been replaced with its analogs bisphenol S (BPS) and bisphenol F (BPF) over the last decade due to health concerns. BPS and BPF are present in relatively high concentrations in different products, such as food products, personal care products, and sales receipts. Both BPS and BPF have similar structural and chemical properties to BPA; therefore, considerable scientific efforts have investigated the safety of their exposure. In this review, we summarize the findings of relevant epidemiological studies investigating the association between urinary concentrations of BPS and/or BPF with the incidence of obesity or diabetes. The results showed that BPS and BPF were detected in many urinary samples at median concentrations ranging from 0.03 to 0.4 µg·L−1. At this exposure level, BPS median urinary concentrations (0.4 µg·L−1) were associated with the development of obesity. At a lower exposure level (0.1–0.03 µg·L−1), two studies showed an association with developing diabetes. For BPF exposure, only one study showed an association with obesity. However, most of the reported studies only assessed BPS exposure levels. Furthermore, we also summarize the findings of experimental studies in vivo and in vitro regarding our aim; results support the possible obesogenic effects/metabolic disorders mediated by BPS and/or BPF exposure. Unexpectedly, BPS may promote worse obesogenic effects than BPA. In addition, the possible mode of action underlying the obesogenic effects of BPS might be attributed to various pathophysiological mechanisms, including estrogenic or androgenic activities, alterations in the gene expression of critical adipogenesis-related markers, and induction of oxidative stress and an inflammatory state. Furthermore, susceptibility to the adverse effects of BPS may be altered by sex differences according to the results of both epidemiological and experimental studies. However, the possible mode of action underlying these sex differences is still unclear. In conclusion, exposure to BPS or BPF may promote the development of obesity and diabetes. Future approaches are highly needed to assess the safety of BPS and BPF regarding their potential effects in promoting metabolic disturbances. Other studies in different populations and settings are highly suggested.
Strategies for Restoring and Managing Ecological Corridors of Freshwater Ecosystem
Authors: Lin Qiaoyan , Song Yu , Zhang Yixin , Hao Jian Li , Wu Zhijie
Published: November 2022

Along with accelerating urbanization and associated anthropogenic disturbance, the structure and function of freshwater ecosystems worldwide are substantially damaged. To improve ecosystem health, and thus enhance the ecosystem security of the urban ecosystem, numbers of management approaches and engineering projects have been applied to mitigate the degradation of freshwaters. Nevertheless, there is still a lack of comprehensive and systematic research on the ecological corridor restoration of freshwater ecosystems; especially for Suzhou Grand Canal, one section of the world’s longest and ancient Grand Canal which is inclined to severe ecosystem degradation. Through investigating the adjacent land use characteristics, habitat quality, vegetation cover, instream water quality, and habitat composition, we aimed to: (i) assess the water quality of the Suzhou Grand Canal; (ii) evaluate the ecological characteristics of the canal ecosystem; (iii) develop strategic countermeasures to restore the ecological corridors for the mitigation of ecological problems. The results demonstrated: a large built area, a smaller ecological zone, a low habitat quality and habitat connectivity, and a high degree of habitat fragmentation within the canal corridor, also a simplified instream habitat composition, and greater nutrient and COD concentrations in the surface water—especially in the upstream and midstream canal. All urbanization-induced multiple stressors, such as land use changes, altered hydrology, and the simplified riparian zone et al., contributed synergistically to the degradation of the canal ecosystem. To alleviate the ecosystem deterioration, three aspects of recommendations were proposed: water pollution control, watershed ecosystem restoration, and ecological network construction. Basically, building a comprehensive watershed ecological network—on the basis of associated ecosystem restoration, and the connection of multi-dimensional ecological corridors—would dramatically increase the maintenance of aquatic–terrestrial system biodiversity, and improve the regional ecological security pattern and watershed resilience toward stochastic future disturbances. This study contributes to the understanding of the ecological challenges and related causes of the canal ecosystem. The integrated strategy introduced in this study provides policymakers, water resource managers, and planners with comprehensive guidelines to restore and manage the ecological corridor of the canal ecosystem. This can be used as a reference in freshwater ecosystems elsewhere, to improve ecosystem stability for supporting the sustainable development of urban ecosystems.
Factors That “Nudge People towards the Healthier” Snacks—A Qualitative Study with Student, Faculty, and Staff Leaders and Decision Makers
Authors: Kirchoff Christie Leanne , Agarwal Rumi , Sanchez Mariana , Palacios Cristina
Published: November 2022

(1) College campuses pose numerous public health challenges for students, faculty and staff. The healthfulness of the snacks available on campuses is lacking, and there is a desire for change among the students and staff. The objective of this study is to understand the perspectives of the students, staff, and decision makers regarding the college campus food environment and the perceived facilitators and barriers to improving it. (2) In-depth interviews were conducted (n = 15) with decision makers in food, policy development, wellness, and nutrition at a large Hispanic-Serving University in South Florida. (3) The key stakeholders shared that educational campaigns, student buy-in, raising awareness around obesity and chronic disease, and the university’s position within the community would all help to facilitate improvements to the snack food environment. However, the participants noted that the complex nature of what is considered to be healthy and what divergent consumers want are significant barriers to improving the snack food environment along with concerns over lost revenue and the corporate structure. (4) These results inform potential focal points for multi-level interventions and inform policy discussions focused on improving the snack food environment at minority-serving universities. Taking strategic actions to improve the snack food environment may aid the students and staff of the university to enhance their diet quality.
Exploration of the Shoulder Internal Rotation’s Influence on Throwing Velocity in Handball Players: A Pilot Study
Authors: García-Buendía Gustavo , Martínez-García Darío , Jerez-Mayorga Daniel , Gómez-López Manuel , Chirosa-Ríos Ignacio Jesús , Chirosa-Ríos Luis Javier
Published: November 2022

The main objective of this study was to test the relationship between shoulder internal rotation strength and standing throwing velocity. A repeated measures cross-sectional study was conducted with 20 professional handball players (mean ± SD; age: 19.28 ± 2.55 years, weight: 81.52 ± 9.66 kg, height: 185 ± 6 cm, BMI: 23.74 ± 1.69). The participants were instructed to perform eight standing throws from the 7 m line of the handball court at maximum velocity to calculate the mean and maximum throwing velocity. An incremental test was performed to calculate the repetition maximum (1-RM) of internal rotation shoulder strength. A Pearson’s correlation analysis with a 95% confidence interval (95% CI) was performed to determine whether correlations existed between dominant arm internal rotation strength characteristics and maximum and mean ball-throwing velocity. There is no correlation between the internal rotation strength of the throwing shoulder and the velocity of the ball in the standing handball throw.
Kinematics Analysis of Male Runners via Forefoot and Rearfoot Strike Strategies: A Preliminary Study
Authors: Chen Chao-Fu , Wu Hui-Ju , Liu Chao , Wang Soun-Cheng
Published: November 2022

This study aimed to explore the kinematic characteristics of males using various foot landing strategies. The participants were fifteen male students from Physical Education College, Huaibei (non-professional runners, who did not have a fixed running landing strategy mode) (mean height = 178.20 cm; mean weight = 67.60 kg; mean age = 19.40 years). In this experiment, the running model of different foot landing strategies (forefoot strike, FFS and rearfoot strike, RFS) were analyzed using two high-speed cameras captured simultaneously at a sampling rate of 100 Hz. According to the results, the runners with better sports performance have shorter contact time, longer flight time, lower duty factor, larger stride angle, faster V COG, greater A COG, and knee and ankle angles which were crucial kinematics factors to enhance the running. Therefore, this study recommends that coaches or researchers can use photography to analyze novice runners who do not have a fixed landing pattern when running with RFS, the characteristics of running style was closely related to the flight times, and running with FFS was closely related to the stride angle.
Effectiveness of Adherence to a Mediterranean Diet in the Management of Overweight Women: The Prospective Interventional Cohort Study
Authors: Poráčová Janka , Uher Ivan , Vašková Hedviga , Kimáková Tatiana , Konečná Mária , Blaščáková Marta Mydlárová , Sedlák Vincent
Published: November 2022

Evidence indicates that unhealthy eating habits constitute multilevel obstacles threatening health and well-being. Studies suggest that consumer choices have turned irremovably towards Western diets. The Mediterranean diet (MD) is considered one of the most effective in preventing and treating overweight and obesity, yet its results and associations are ambiguous. This explanatory research aims to examine the effect of the MD on anthropometric and biochemical variables in 181 females from an Eastern European country. The sample was divided into three distinct clusters based on age (tricenarian, quadragenarian, and quinquagenarian). Anthropometric and biochemical examinations in the three-month MD program plan failed to provide convincing evidence of the benefits of the MD on selected integrands. However, total body fat (FATP) values between groups showed a significant difference (p ≤ 0.032) between groups A and C (p ≤ 0.029), which can be attributed to the age of the cohort (30–39 vs. 50–60 years). Values in groups A and B (p ≤ 0.001) and C and A (p ≤ 0.001) were significant between the cohorts but did not indicate any changes in visceral fat (VFATL) in the individual groups. The presented findings can have implications for further investigation and the development of more comprehensive instruments, incorporating critical add-on constituents that will be appropriate to monitor, evaluate, and predict body weight management in experimentation.
Multistage Psychometric Testing of the Homeless Health Access to Care Tool
Authors: Currie Jane , Grech Elizabeth , Yee Jasmine , Aitkenhead Amy , Jones Lee
Published: November 2022

People experiencing homelessness find it challenging to access the healthcare they so desperately need. To address this, we have developed the Homeless Health Access to Care Tool, which assesses health related vulnerability (burden of injury and/or illness and ability to access healthcare) and can be used to prioritize people for access to healthcare. Here, we report the initial psychometrics of the Homeless Health Access to Care Tool. To assess interrater reliability, clinician participants were invited to instinctually rate the health-related vulnerability of 18-fictional case studies and then apply the Homeless Health Access to Care Tool to these same case studies. To assess convergent validity, the Homeless Health Access to Care Tool and the tool it was adapted from, the Australian Vulnerability Index Service Prioritization Decision Assistance Tool were administered to people experiencing homelessness. Feedback was sought from the participants receiving these two tools and from those administering them. The Homeless Health Access to Care Tool demonstrated a high interrater reliability and internal consistency. Participants using and receiving the Homeless Health Access to Care Tool reported it as straightforward, unintrusive and clear. Median time of administration was 7 min 29 s (SD 118.03 s). Convergent validity was established for the Homeless Health Access to Care Tool with a moderate correlation (r = 0.567) with the total score of the Australian Vulnerability Index Service Prioritization Decision Assistance Tool. Findings suggest that the Homeless Health Access to Care Tool is feasible and reliable. Larger samples are required to report construct validity.
Mercury Contamination in Fish and Its Effects on the Health of Pregnant Women and Their Fetuses, and Guidance for Fish Consumption—A Narrative Review
Authors: Chen Bojian , Dong Shiyuan
Published: November 2022

As a principal source of long-chain omega-3 fatty acids (3FAs), which provide vital health benefits, fish consumption also comes with the additional benefit of being rich in diverse nutrients (e.g., vitamins and selenium, high in proteins and low in saturated fats, etc.). The consumption of fish and other seafood products has been significantly promoted universally, given that fish is an important part of a healthy diet. However, many documents indicate that fish may also be a potential source of exposure to chemical pollutants, especially mercury (Hg) (one of the top ten chemicals or groups of chemicals of concern worldwide), and this is a grave concern for many consumers, especially pregnant women, as this could affect their fetuses. In this review, the definition of Hg and its forms and mode of entrance into fish are introduced in detail and, moreover, the bio-accumulation of Hg in fish and its toxicity and action mechanisms on fish and humans, especially considering the health of pregnant women and their fetuses after the daily intake of fish, are also reviewed. Finally, some feasible and constructive suggestions and guidelines are recommended for the specific group of pregnant women for the consumption of balanced and appropriate fish diets in a rational manner.
Association of Infection with Different SARS-CoV-2 Variants during Pregnancy with Maternal and Perinatal Outcomes: A Systematic Review and Meta-Analysis
Authors: Deng Jie , Ma Yirui , Liu Qiao , Du Min , Liu Min , Liu Jue
Published: November 2022

The aim of this study is to review the currently available data, and to explore the association of infection with different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants during pregnancy with maternal and perinatal outcomes in the real world. Observational cohort studies were analyzed that described the maternal and perinatal outcomes of infection with different SARS-CoV-2 variants during pregnancy. Random-effects inverse-variance models were used to evaluate the pooled prevalence (PP) and its 95% confidence interval (CI) for maternal and perinatal outcomes. Random effects were used to estimate the pooled odds ratios (OR) and their 95% CI for different outcomes between Delta and pre-Delta periods, and between Omicron and Delta periods. Eighteen studies, involving a total of 133,058 cases of SARS-CoV-2 infection during pregnancy (99,567 cases of SARS-CoV-2 wild type or pre-variant infection and 33,494 cases of SARS-CoV-2 variant infections), were included in this meta-analysis. Among pregnant women with SARS-CoV-2 infections, the PPs for required respiratory support, severe or critical illness, intensive care unit (ICU) admission, maternal death, and preterm birth <37 weeks were, respectively, 27.24% (95%CI, 20.51–33.97%), 24.96% (95%CI, 15.96–33.96%), 11.31% (95%CI, 4.00–18.61%), 4.20% (95%CI, 1.43–6.97%), and 33.85% (95%CI, 21.54–46.17%) in the Delta period, which were higher than those in the pre-Delta period, while the corresponding PPs were, respectively, 10.74% (95%CI, 6.05–15.46%), 11.99% (95%CI, 6.23–17.74%), 4.17% (95%CI, 1.53–6.80%), 0.63% (95%CI, 0.05–1.20%), and 18.58% (95%CI, 9.52–27.65%). The PPs for required respiratory support, severe or critical illness, and ICU admission were, respectively, 2.63% (95%CI, 0.98–4.28%), 1.11% (95%CI, 0.29–1.94%), and 1.83% (95%CI, 0.85–2.81%) in the Omicron period, which were lower than those in the pre-Delta and Delta periods. These results suggest that Omicron infections are associated with less severe maternal and neonatal adverse outcomes, though maternal ICU admission, the need for respiratory support, and preterm birth did also occur with Omicron infections. Since Omicron is currently the predominant strain globally, and has the highest rates of transmission, it is still important to remain vigilant in protecting the vulnerable populations of mothers and infants. In particular, obstetricians and gynecologists should not ignore the adverse risks of maternal ICU admission, respiratory support, and preterm births in pregnant patients with SARS-CoV-2 infections, in order to protect the health of mothers and infants.
Social Support and Loneliness among Chinese Rural-to-Urban Migrant Children: A Moderated Mediation Analysis of the Roles of Social Competence and Stress Mindset
Authors: Chen Luxi , Yang Fang
Published: November 2022

Social support has been an important social-contextual protective factor against loneliness. However, how individual-level protective factors, such as social competence and a positive stress mindset, may jointly influence the relationship between social support and loneliness is less known. This study examined to what extent the link between social support and loneliness would be mediated by social competence and moderated by stress mindset among migrant children. In total, 198 rural-to-urban migrant children aged 10–14 years (56.1% girls) in Beijing, China, completed a set of self-reported questionnaires. A moderated mediation analysis was performed. We found that perceived social support was associated with a lower level of loneliness, and this association was significant only for migrant children holding a positive stress mindset (indicated by a high ratio of the stress-is-a-challenge mindset to the stress-is-a-threat mindset). Notably, across children with different stress mindsets, perceived social support was indirectly related to a lower level of loneliness through greater social competence. Our findings suggest that social competence and a stress-is-a-challenge mindset are important individual-level protective factors for migrant children to overcome loneliness. Social competence can carry the effect of social support, and a stress-is-a-challenge mindset can optimize the effect of environmental resources on mental health.
Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea
Authors: Huh Da-An , Chae Woo-Ri , Choi Yun-Hee , Kang Min-Sung , Lee Yong-Jin , Moon Kyong-Whan
Published: November 2022

Korea was one of the major consumers of asbestos in the late 1900s, and asbestos-related disease patients have been reported continuously to date, owing to long disease latency. Several studies have been conducted to predict the future incidence of malignant mesothelioma and lung cancer in Korea, but little is understood about the latency time. Therefore, the aim of this study is to estimate the latency period of malignant mesothelioma and asbestos-related lung cancer in Korea and its determinants. We obtained information from the Environmental Health Centers for Asbestos in Korea on the history of asbestos exposure and demographic characteristics of 1933 patients with malignant mesothelioma and asbestos-related lung cancer. In our study, the latency periods for malignant mesothelioma and lung cancer were 33.7 and 40.1 years, respectively. Regardless of the disease type, those with a history of exposure related to the production of asbestos-containing products or asbestos factories had the shortest latency period. In addition, we observed that those who worked in or lived near asbestos mines tended to have a relatively long disease latency. Smoking was associated with shorter latency, but no linear relationship between the lifetime smoking amount (expressed in pack years) and latent time was observed. In addition, the age of initial exposure showed a negative linear association with the latency period for mesothelioma and lung cancer.
Analysis of Dust Emission Characteristics of Peanut Whole-Feed Harvesting Based on Total Amount Collection Method
Authors: Xu Hongbo , Zhang Peng , Hu Zhichao , Mao Enrong , You Zhaoyan , Du Yuefeng
Published: November 2022

In view of the lack of a total amount collection method of dust emitted from a peanut whole-feed harvester and the unknown characteristic parameters of dust emission, a total amount dust collection method based on the combined action of centrifugation and filtration was proposed. The structural parameters of a total amount dust collection device were designed through theoretical analysis. On this basis, the production of a total amount dust collection device and a total amount dust collection test of the peanut whole-feed harvester were completed. The test showed that the total amount dust collection device could meet the needs of dust emission characteristics research. After analyzing the collected dust, it was found that the emitted particles were a mixture of soil particles and fiber particles. When the engine speed of the harvester was increased from 1600 rpm to 2400 rpm, the total emission rate increased from 3.36% to 4.28%, and the particulate emission rate increased from 1.44% to 2.63%; it also caused 4.29~4.98% of seedling blowing loss. The emission proportion of soil particles was reduced from 58.93% to 44.25%, and the emission proportion of fiber particles was increased from 41.07% to 55.75%. Among the emitted particles, the particle size peak of soil particles was concentrated at 22.9~30.2 μm; the particle size peak of fiber particles was concentrated at 478.6~631.0 μm. The research method and results can provide a reference for the optimization of dust reduction and emission reduction of peanut whole-feed harvesters and similar crop harvesters.
Dental Reimplantation Treatment and Clinical Care for Patients with Previous Implant Failure—A Retrospective Study
Authors: Yang Jiakang , Siow Lixuen , Zhang Xinyue , Wang Yu , Wang Huiming , Wang Baixiang
Published: November 2022

(1) Objectives: This study evaluated the clinical outcomes of dental implants placed in previously failed sites and discussed the risk factors that mattered in reimplantation. (2) Methods: All the cases by one specific implantologist during his first five years of clinical practice were screened, with a focus on those who received reimplantation. The clinical outcomes were assessed, including the implant survival, peri-implant health, and patients’ satisfaction. (3) Results: 28 patients (31 implants) were recorded as failures from 847 patients (1269 implants), with a 2.4% overall failure rate at the implant level, of whom 19 patients (21 implants) received reimplantation treatment. After a mean follow-up of 33.7 ± 10.1 months (95% CI 29.1–38.3 months), 20 implants remained functional, but 1 implant revealed a secondary early failure, indicating a 95.2% overall survival rate. The mean probing depth (PD), modified sulcus bleeding index (mSBI), and marginal bone loss (MBL) of the surviving reinserted implants were 2.7 ± 0.6 mm (95% CI 2.5–3.0 mm), 0.7 ± 0.5 (95% CI 0.5–1.0), and 0.5 ± 0.6 mm (95% CI 0.3–0.8 mm), respectively. Embedded healing occurred more frequently in the reinserted implants than in the primary implants (p = 0.052). The patients’ satisfaction suffered from implant failure, but a successful reimplantation could reverse it with close doctor–patient communication. (4) Conclusions: Reimplantation treatment was recommended, based on a thorough evaluation and consideration of the risk factors combined with effective communication with the patients.
Exploring the Retail Food Environment Surrounding Two Secondary Schools with Predominantly Pacific Populations in Tonga and New Zealand to Enable the Development of Mapping Methods Appropriate for Testing in a Classroom
Authors: Pauuvale Alvina F. , Vickers Mark H. , Pamaka Soana , Apelu Dorothy , Fehoko ‘Anaseini , ‘Ofanoa Malakai , Bay Jacquie L.
Published: November 2022

Rates of noncommunicable diseases (NCDs) are disproportionately high among people of Pacific ethnicity. Nutrition-related environmental exposures including food access and quality contribute to the matrix of factors impacting risk. Preventative interventions in adolescence and the opportunity to integrate health promotion into school-based learning are often overlooked. This study tested the potential of a low-cost method to map the retail food environment in a 1 km radius of two secondary schools in low socioeconomic communities with predominantly Pacific populations, in Tonga and New Zealand (NZ). Mapping utilized Google Earth, Google Maps, government maps, and observations. A rubric was developed to categorize food quality. Outlets within a 1 km radius of each school, (Tonga, n = 150; NZ, n = 52) stocked predominantly unhealthy foods. The NZ data compared favorably to previous studies, indicating the method was valid. The Tongan data is novel and indicates that alternative strategies can be used when access to GIS-type tools is limited. The method produced visual data that has the potential to be analyzed using strategies appropriate for secondary schools. The method should now be tested in classrooms to assess its potential to support school-age students to engage in mapping and critiquing the retail food environment.
Occupational Well-Being of Multidisciplinary PHC Teams: Barriers/Facilitators and Negotiations to Improve Working Conditions
Authors: Cezar-Vaz Marta Regina , Xavier Daiani Modernel , Bonow Clarice Alves , Vaz Joana Cezar , Cardoso Letícia Silveira , Sant’Anna Cynthia Fontella , Costa Valdecir Zavarese da , Nery Carlos Henrique Cardona , Loureiro Helena Maria Almeida Macedo
Published: November 2022

Well-being at work is one of the factors determining healthy work conditions and is perceived by workers as a positive psychological state. In this study, the concept of well-being at work was used together with occupational functionality (i.e., current health state, current work environment, and barriers/facilitators to implementing well-being at work), occupational risk perception, and proactivity/negotiations held by workers to improve working conditions. In this context, the objectives were to identify the socio-demographic and occupational characteristics independently associated with levels of well-being at work of the multidisciplinary PHC health team; detect barriers or facilitators resulting from the attitudes of colleagues, community members, and managers that influence the well-being at work of the multidisciplinary health team; and identify with whom and what reasons led health workers to become proactive and negotiate improved working conditions. This cross-sectional study addressed 338 health workers from the multidisciplinary teams of PHC outpatient services in the extreme south of Brazil. Multivariate linear regression models were adopted to analyze data. The results show various independent associations with levels of well-being at work. Nursing workers (technicians and nurses) more frequently expressed job commitment and job satisfaction. Difficulties in solving problems and performing work routines, and co-workers’ attitudes directly influence the well-being of the PHC team members. Risk perception (physical and chemical) also influences well-being. Negotiations in which PHC managers engaged to improve working conditions appeared as a significant predictor of job commitment, job satisfaction, and job involvement. The results reveal that well-being at work is an important indicator of the potential of workers’ proactivity in negotiating improved working conditions.
The Impact of Managers’ Environmental Cognition on Urban Public Service Innovation from the Perspective of Green Ecology
Authors: Liu Ling , Zhou Yuanyuan
Published: November 2022

With the continuous improvement in urban managers’ cognition of green ecology, it is a hot issue in current research to explore the role of managers’ cognition on urban public service innovation from the perspective of green ecology. The main purpose of this study was to explore ways to build green ecological cities and provide high-quality urban public services based on managers’ environmental cognition. Through sorting out and discriminating the concepts related to green ecology, this research improves the current theoretical system related to green ecological city services. A theoretical model of a green ecological city public service system was constructed, and its influence path and effect on green ecological city public service innovation were analyzed in detail. This research provides a good tool and method for follow-up research to better understand the composition and innovation of green ecological city public service systems.
Gaps between Activities of Daily Living Performance and Capacity in People with Mild Dementia
Authors: Nakanishi Kosuke , Yamaga Takayoshi , Ikeya Masanao
Published: November 2022

Persons with mild dementia can effectively maintain and improve their quality of life (QOL) by regularly performing their daily activities. However, research on activities of daily living (ADL) in this population often fails to distinguish between ADL performance and ADL capability, that is, actual independence in daily lives and potential independence in an ideal setting. This study aimed to identify the potential gaps between ADL performance and capability in individuals with mild dementia. A total of 137 community-dwelling older adults (aged ≥ 65 years) who had been diagnosed with dementia and assessed as 0.5 and 1 on a global clinical dementia rating (CDR). Participants were evaluated for basic ADL (BADL) and instrumental ADL (IADL) using the Hyogo Activities of Daily Living Scale (HADLS). Around 35 individuals who met the inclusion criteria were enrolled in the study. BADL performance and BADL capacity were not significantly different (p = 0.128); however, participants rated IADL capacity significantly higher than IADL performance (p < 0.01). Gaps between performance and capability were observed for IADL but not for BADL. This study distinguishes between ADL performance and capability in individuals with mild dementia and is the first to identify the IADL-specific gap between these two components; pertinent targeted interventions are vital in closing this gap. Environmental adjustments are important to improve QOL of persons with mild dementia.
Dealing with Loved Ones’ Addiction: Development of an App to Cope with Caregivers’ Stress
Authors: Renati Roberta , Bonfiglio Natale Salvatore , Rollo Dolores
Published: November 2022

Caregivers remain the primary source of attachment, nurturing, and socialization for human beings in our current society. Family caregivers provide 11 to 100 h of care per week to their loved ones, including emotional and social support, assistance with transportation, home care, and so on. However, caregivers find the workload challenging due to fatigue, burnout, depression, anxiety, and sleep disturbances, and sometimes also from an excessive burden. Caregiver burden and stress ultimately negatively affect family members and caregivers. The caregiver is then at risk of developing deleterious physical, psychological, social, and emotional problems such as mood and anxiety disorders. Mobile health applications (mHealth applications) can be a solution to help family caregivers care for their loved ones and also for themselves. In this study, we present the development of an mHealth application for caregivers of persons with substance use and tested its usability. We used a user-centered design and intervention (UCDI) approach to develop the app by conducting a focus group with parents of individuals with addiction problems. Four key themes were identified during the focus group: (i) information section, (ii) self-care section, (iii) how-to: stress-reduction section, and (iv) chat section. The final app was developed with the software vendor and divided into several sections that were useful for managing psychological problems (such as stress or anxiety), informing about addiction and behavioral dependency problems, and helping users find a professional or services nearby. An analysis of the results of a usability test related to the app administered to a subsample of the focus group showed that the app provided ease of use, usefulness, and satisfaction.
Condemn or Treat? The Influence of Adults’ Stigmatizing Attitudes on Mental Health Service Use for Children
Authors: Lange Stephanie , Gossmann Emily , Hofmann Sophie , Fegert Jörg M.
Published: November 2022

Stigmatizing attitudes towards mental disorders influence parents’ help-seeking behavior for their child’s mental health problems. As untreated mental disorders can cause morbidity and mortality, such parental attitudes are a serious barrier for public health promotion. Therefore, the help-seeking readiness in a distressed child’s broad social environment is essential. However, the role of stigma was unexplored in this context. This study empirically investigated the influence of adults’ stigmatizing attitudes towards mentally disabled people on their readiness to seek professional help for children’s mental health issues. Data from a representative German sample (N = 1906; 52% female) were collected between July and October 2021. A heteroscedastic ordered probit model was used for estimation. An empirical analysis provides evidence for a significant negative relationship between adults’ stigmatizing attitudes and their readiness to initiate mental health support for children (ß = −0.01; p < 0.001). Support acceptance seems to be independent of having children. To tackle stigmatizing attitudes and to promote public health, mental health literacy should be fostered through broad-based approaches. Awareness should be raised that children are also entitled to mental health care, just as they are in other health areas. Policy makers need to promote comprehensive information about mental illnesses and create incentives for acute and preventive service use.
Interparental and Intergenerational Co-parenting Conflict and Adolescent Academic Performance: The Mediating Roles of Adolescent Academic Engagement and Depression
Authors: Yang Hexin , Wu Chaoyue , Chen Ji-Kang
Published: November 2022

While a link between co-parenting conflict and academic performance is frequently assumed, studies on this association have shown inconsistent results. In addition, academic engagement and depression can potentially mediate the association between co-parenting conflict and academic performance. However, studies have not tested this proposition. This paper examined the direct effect of co-parenting conflict on adolescent academic performance and the mediating effect of academic engagement and depression. Using data from a nationally representative survey, the 2020 China Family Panel Studies (CFPS), we constructed a sample of 1989 dyads of adolescents (aged 10 to 15) and their primary caregivers in China. The structural equation model analysis revealed that co-parenting conflict was not directly linked with academic performance but was indirectly associated with adolescent academic performance through academic engagement and depression. The findings provide empirical support that academic engagement and depression play important mediating roles in the relationship between co-parenting conflict and adolescent academic performance. Future intervention programs aimed at promoting adolescent academic performance may consider a family-oriented approach to identify adolescents from families with co-parenting conflict and provide them with professional support.
School Built Environments and Bullying Behaviour: A Conceptual Model Based on Qualitative Interviews
Authors: Francis Jacinta , Trapp Gina , Pearce Natasha , Burns Sharyn , Cross Donna
Published: November 2022

Interest in how the school built environment impacts bullying behaviour has gained momentum in recent years. While numerous studies have identified locations within schools where bullying frequently occurs, few studies have investigated the potential conceptual pathways linking school locations to bullying behaviour. This study aimed to (i) identify school built environment factors that may prevent or facilitate bullying behaviour in primary and secondary schools; and (ii) develop a conceptual model of potential pathways between the school built environment and bullying behaviour for future anti-bullying intervention research. Seventy individual semi-structured interviews were conducted between May and December 2020, with policymakers (n = 22), school staff (n = 12), parents (n = 18), and students (n = 18). School staff, parents and students, were recruited from six metropolitan primary and secondary schools in Perth, Western Australia. Interviews were conducted online and face-to-face using semi-structured interview guides. A thematic analysis was undertaken. Participants identified school bullying locations (e.g., locker areas, bathrooms, corridors) and built environment factors linked to bullying behaviour via (i) visibility and supervision; (ii) physical and psychological comfort and safety; and (iii) social-emotional competencies. The findings have policy and practice implications regarding the design of school built environments to prevent bullying behaviour.
Beyond the Digital Competencies of Medical Students: Concerns over Integrating Data Science Basics into the Medical Curriculum
Authors: Lungeanu Diana , Petrica Alina , Lupusoru Raluca , Marza Adina Maria , Mederle Ovidiu Alexandru , Timar Bogdan
Published: November 2022

Introduction. Data science is becoming increasingly prominent in the medical profession, in the face of the COVID-19 pandemic, presenting additional challenges and opportunities for medical education. We retrospectively appraised the existing biomedical informatics (BMI) and biostatistics courses taught to students enrolled in a six-year medical program. Methods. An anonymous cross-sectional survey was conducted among 121 students in their fourth year, with regard to the courses they previously attended, in contrast with the ongoing emergency medicine (EM) course during the first semester of the academic year 2020–2021, when all activities went online. The questionnaire included opinion items about courses and self-assessed knowledge, and questions probing into the respondents’ familiarity with the basics of data science. Results. Appreciation of the EM course was high, with a median (IQR) score of 9 (7–10) on a scale from 1 to 10. The overall scores for the BMI and biostatistics were 7 (5–9) and 8 (5–9), respectively. These latter scores were strongly correlated (Spearman correlation coefficient R = 0.869, p < 0.001). We found no correlation between measured and self-assessed knowledge of data science (R = 0.107, p = 0.246), but the latter was fairly and significantly correlated with the perceived usefulness of the courses. Conclusions. The keystone of this different perception of EM versus data science was the courses’ apparent value to the medical profession. The following conclusions could be drawn: (a) objective assessments of residual knowledge of the basics of data science do not necessarily correlate with the students’ subjective appraisal and opinion of the field or courses; (b) medical students need to see the explicit connection between interdisciplinary or complementary courses and the medical profession; and (c) courses on information technology and data science would better suit a distributed approach across the medical curriculum.
GRP78 Activity Moderation as a Therapeutic Treatment against Obesity
Authors: Pan Dongjin , Yang Yunzhu , Nong Aihua , Tang Zhenzhou , Li Qing X.
Published: November 2022

Glucose-regulated protein 78 (GRP78), a molecular chaperone, is overexpressed in patients suffering from obesity, fatty liver, hyperlipidemia and diabetes. GRP78, therefore, can be not only a biomarker to predict the progression and prognosis of obesity and metabolic diseases but also a potential therapeutic target for anti-obesity treatment. In this paper, GRP78 inhibitors targeting its ATPase domain have been reviewed. Small molecules and proteins that directly bind GRP78 have been described. Putative mechanisms of GRP78 in regulating lipid metabolism were also summarized so as to investigate the role of GRP78 in obesity and other related diseases and provide a theoretical basis for the development and design of anti-obesity drugs targeting GRP78.
COVID-19 Case Management Outcomes Amongst Diabetes and Hypertensive Patients in the United Arab Emirates: A Prospective Study
Authors: Alkhemeiri Aysha , Al Zaabi Shaikha , Lakshmanan Jeyaseelan , El-Khatib Ziad , Awofeso Niyi
Published: November 2022

The global pandemic of the novel Coronavirus infection 2019 (COVID-19) challenged the care of comorbid patients. The risk imposed by COVID-19 on diabetes patients is multisystemic, exponential, and involves glucose dysregulation. The increased burden for diabetes patients infected with COVID-19 is substantial in countries with a high prevalence of diabetics, such as the United Arab Emirates (UAE). This study aims to explore the prevalence of diabetes, clinical characteristic, and outcomes of patients admitted for COVID-19 treatment with or without a concurrent preadmission diagnosis of diabetes. A prospective study was performed on 1199 adults admitted with confirmed COVID-19 from December 2020 to April 2021 to a single hospital in the UAE. The study compared the demographics, clinical characteristics, and outcomes in COVID-19-infected patients with diabetes to patients without diabetes. The study endpoints include the development of new-onset diabetes, admission to ICU, trends in the blood glucose levels, and death. A total of 1199 patients (390 with diabetes) were included in the study. A diabetes prevalence was detected among 9.8% of the study population. Among the diabetes group, 10.8% were morbidly obese, 65.4% had associated hypertension, and 18.9% had coronary artery disease. Diabetes patients showed higher rates of ICU admission (11.1% vs. 7.1%), NIV requirement (9.6% vs. 6.4%), and intubation (5.45% vs. 2%) compared to the non-diabetes group. Advanced age was a predictor of a worsening COVID-19 course, while diabetes (p < 0.050) and hypertension (p < 0.025) were significant predictors of death from COVID-19. Nearly three-fourths (284 (73.4%)) of the diabetic patients developed worsened hyperglycemia as compared to one-fifth (171 (20.9%)) of the nondiabetic patients. New-onset diabetes was detected in 9.8% of COVID-19 patients. COVID-19 severity is higher in the presence of diabetes and is associated with worsening hyperglycemia and poor clinical outcomes. Preexisting hypertension is a predictor of COVID-19 severity and death.
Seroprevalence of Chlamydia trachomatis and Associated Factors among Vulnerable Riverine in the Brazilian Amazon
Authors: Galvão José Jorge da Silva , Cunha Carlos Leonardo Figueiredo , Pinho Ellen Christiane Correa , Paiva David de Jesus da Silva , de Castro Nádile Juliane Costa , Nascimento Valéria Gabriele Caldas , de Azevedo Junior Wanderson Santiago , da Silva Richardson Augusto Rosendo , Feitosa Rosimar Neris Martins , Vallinoto Antonio Carlos Rosário , Botelho Eliã Pinheiro , Ferreira Glenda Roberta Oliveira Naiff
Published: November 2022

Due to social and individual conditions and access to health services, Amazonian riverside populations are highly vulnerable to sexually transmitted infections, including Chlamydia trachomatis. The aim is to estimate the seroprevalence of Chlamydia trachomatis and analyze the associated factors among riverside dwellers in a capital city in the Brazilian Amazon. A cross-sectional study was carried out with residents of the Combu Island, Belém. The study sample was calculated using the population survey technique in the EPI INFO. Only people aged 18 and over were included. ELISA serology was performed to detect antibodies against Chlamydia trachomatis. For data collection, a form containing vulnerability factor questions was applied. Binary regression analysis was performed using the Minitab 20 program. The study sample consisted of 325 participants. The prevalence of IgG/IgM antibodies against Chlamydia trachomatis was 22.2% and 5.5%, respectively. In the multiple regression, only participants with a broken condom were more likely to have antibodies against the bacteria (OR: 1.90; 95% CI: 1.01; 3.37; p = 0.046). Seroprevalence was associated with condom breakage. This factor demonstrates that despite having an attitude towards condom use, probably, they may have inadequate knowledge about the correct practice of introduction.
Occupational Health of Education Personnel—The Role of Job Crafting and Other Control Strategies on Healthy Ageing at Work
Authors: Tsai Min-Chien , Wang Sy-Feng , Gray Nicola J. , Jourdan Didier
Published: November 2022

This article looks at the strategies that influence healthy ageing at work from the motivational theory of life span development (MTD). It aims to better understand the influence of job crafting as a selective primary control, help-seeking as a compensatory primary control, positive reappraisal as a selective secondary control, and downward social comparison and downgrading expectation as a compensatory secondary control on healthy ageing at work (work engagement, health, and motivation to continue working after retirement). A total of 386 educational personnel participated in the study. This study used hierarchical regression analysis to test incremental validity, supplemented with confirmatory factor analysis and structural equation modelling as a solution to solve the potential error problems caused. The results show that job crafting is positively correlated with healthy ageing at work. Positive reappraisal and downward social comparison showed incremental validity in predicting healthy ageing at work beyond job crafting among the middle-aged group (45–65-years-old); in particular, positive reappraisal was the determinant of healthy ageing at work among the middle-aged group. However, both help-seeking and downgrading expectation did not show incremental validity. This study can contribute to the evolution of career development interventions and human resource management focused on supporting older people at work.