bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of osteochondral sample collection guided by computed tomography and magnetic resonance imaging for early detection of osteoarthritis in centrodistal joints of young Icelandic horses
Authors: Ley Charles J. , Ekman Stina , Dahlberg Leif E. , Björnsdóttir Sigríður , Hansson Kerstin
Published: May 2013

Objective—To evaluate the use of CT and MRI for guidance of osteochondral sample collection for histologic detection of early osteoarthritic lesions in centrodistal (distal intertarsal) joints of horses.

Sample —Right tarsal joints from the cadavers of 24 Icelandic horses aged 29 to 31 months.

Procedures—CT and MRI were used to evaluate the extent of suspected osteoarthritic changes in centrodistal joints, which were graded with a semiquantitative system. The anatomic regions with the highest grade of change were identified, and osteochondral samples were obtained from these regions. Samples were also obtained from the same centrodistal joints at predetermined sites. Histologic examination of all samples was performed, with samples classified as negative or positive for osteoarthritis, and results were compared between sample collection methods.

Results—Histologic examination revealed osteoarthritic lesions in 29% (7/24) of centrodistal joints with the predetermined method and in 63% (15/24) with the image-guided method. Significant associations were identified between histologic osteoarthritis detection and the summed image-guided sample collection site image grades, central osteophytes, articular cartilage thickness abnormalities, grade 2 articular mineralization front defects, and grade 2 marginal osteophytes.

Conclusions and Clinical Relevance—CT and MRI aided the detection of focal changes suggestive of early-stage osteoarthritis in the centrodistal joints of equine cadavers and may be useful for detection of similar disease in live horses. The first morphological changes of centrodistal joint osteoarthritis were suspected to be in the articular cartilage and the articular mineralization front regions.
Measurement repeatability of tibial tuberosity-trochlear groove offset distance in red fox (Vulpes vulpes) cadavers
Authors: Miles James E. , Jensen Bente R. , Kirpensteijn Jolle , Svalastoga Eiliv L. , Eriksen Thomas
Published: May 2013

Objective—To describe CT image reconstruction criteria for measurement of the tibial tuberosity-trochlear groove (TT-TG) offset distance, evaluate intra- and inter-reconstruction repeatability, and identify key sources of error in the measurement technique, as determined in vulpine hind limbs.

Animals—12 red fox (Vulpes vulpes) cadavers.

Procedures—CT images of each hind limb in intact cadavers were obtained; at 1-week intervals, 3 reconstructions were performed that were based on 1 plane passing through the centers of the femoral head and medial condyle and parallel to the caudal femoral condyles, 1 plane aligned with the femoral trochlea, and a third orthogonal plane. Randomized and anonymized reconstructions were assessed for TT-TG offset distance with a single-image technique by 1 observer, and inter-reconstruction repeatability and intra- and inter-reconstruction measurement repeatability were assessed via the repeatability coefficient and intraclass correlation coefficient.

Results—Multiplanar reconstructions of hind limb images were repeatedly made to within a few degrees of each other. Intra- and inter-reconstruction repeatability for TT-TG offset distance measurement was good. Repeatability was most affected by accurate identification of the tibial tuberosity and femoral trochlea landmarks.

Conclusions and Clinical Relevance—Results obtained from vulpine hind limb CT images indicated that reconstructions can be made with a high degree of repeatability when based on strictly defined and applied criteria. The TT-TG offset distance has potential as an objective assessment of alignment of the distal portion of the quadriceps mechanism; its use as an aid in case selection for corrective femoral osteotomy among dogs with medial patellar luxation warrants investigation.
Systemic immune responses in Cytauxzoon felis-infected domestic cats
Authors: Frontera-Acevedo Karelma , Balsone Nicole M. , Dugan Melissa A. , Makemson Cheryl R. , Sellers Llewelyn B. , Brown Holly M. , Peterson David S. , Creevy Kate E. , Garner Bridget C. , Sakamoto Kaori
Published: May 2013

Objective—To characterize systemic immune responses in Cytauxzoon felis-infected cats.

Sample—Blood and lung samples obtained from 27 cats.

Procedures—Cats were allocated into 4 groups: cats that died of cytauxzoonosis, acutely ill C felis-infected cats, healthy survivors of C felis infection, and healthy uninfected cats. Serum concentrations of tumor necrosis factor-α and interleukin-1 β were measured and serum proteins characterized. Blood smears were stained immunocytochemically and used to assess immunoglobulin deposition. Immunohistochemical expression of CD18 and tumor necrosis factor-α were compared in lung tissues obtained from cats that died and healthy uninfected cats. A real-time reverse-transcription PCR assay for CD18 expression was performed on selected blood samples from all groups.

Results—Concentrations of both cytokines were greater and serum albumin concentrations were significantly lower in cats that died of cytauxzoonosis, compared with results for all other groups. Erythrocytes from acutely ill cats and survivors of C felis infection had staining for plasmalemmal IgM, whereas erythrocytes from the other groups did not. Increased staining of C felis-infected monocytes and interstitial neutrophils for CD18 was detected. The real-time reverse-transcription PCR assay confirmed a relative increase in CD18 expression in cats that died of cytauxzoonosis and acutely ill cats, compared with expression in other groups. Immunostaining for TNF-α in lung samples confirmed a local proinflammatory response.

Conclusions and Clinical Relevance—Results indicated immunopathologic responses were greater in cats that died of C felis infection than in cats that survived C felis infection.
Acute and chronic effects of tepoxalin on kidney function in dogs with chronic kidney disease and osteoarthritis
Authors: Lomas Amy L. , Lyon Shane D. , Sanderson Michael W. , Grauer Gregory F.
Published: May 2013

Objective—To determine whether tepoxalin alters kidney function in dogs with chronic kidney disease (CKD).

Animals—16 dogs with CKD (International Renal Interest Society stage 2 or 3) and osteoarthritis.

Procedures—Kidney function was assessed via serum biochemical analysis, urinalysis, urine protein-to-creatinine concentration ratio, urine γ-glutamyl transpeptidase-to-creatinine concentration ratio, iohexol plasma clearance, and indirect blood pressure measurement twice before treatment. Dogs received tepoxalin (10 mg/kg, PO, q 24 h) for 28 days (acute phase; n = 16) and an additional 6 months (chronic phase; 10). Recheck examinations were performed weekly (acute phase) and at 1, 3, and 6 months (chronic phase). Kidney function variables were analyzed via repeated-measures ANOVA.

Results—There was no difference over time for any variables in dogs completing both phases of the study. Adverse drug events (ADEs) resulting in discontinuation of tepoxalin administration included increased serum creatinine concentration (1 dog; week 1), collapse (1 dog; week 1), increased liver enzyme activities (1 dog; week 4), vomiting and diarrhea (1 dog; week 8), hematochezia (1 dog; week 24), and gastrointestinal ulceration or perforation (1 dog; week 26). Preexisting medical conditions and concomitant drug use may have contributed to ADEs. Kidney function was not affected in the latter 5 dogs. Discontinuation of tepoxalin administration stabilized kidney function in the former dog and resolved the ADEs in 4 of the 5 latter dogs.

Conclusions and Clinical Relevance—Tepoxalin may be used, with appropriate monitoring, in dogs with International Renal Interest Society stage 2 or 3 CKD and osteoarthritis.
Specific serology for emerging human coronaviruses by protein microarray
Authors: Reusken C , Mou H , Godeke G J , van der Hoek L , Meyer B , Müller M A , Haagmans B , de Sousa R , Schuurman N , Dittmer U , Rottier P , Osterhaus A , Drosten C , Bosch B J , Koopmans M
Published: May 2013

We present a serological assay for the specific detection of IgM and IgG antibodies against the emerging human coronavirus hCoV-EMC and the SARS-CoV based on protein microarray technology. The assay uses the S1 receptor-binding subunit of the spike protein of hCoV-EMC and SARS-CoV as antigens. The assay has been validated extensively using putative cross-reacting sera of patient cohorts exposed to the four common hCoVs and sera from convalescent patients infected with hCoV-EMC or SARS-CoV.
More reasons to dread rain on vacation? Dengue fever in 42 German and United Kingdom Madeira tourists during autumn 2012
Authors: Frank C , Höhle M , Stark K , Lawrence J
Published: May 2013

In October and November 2012 residents and tourists in the Autonomous Region of Madeira, Portugal, were affected by dengue fever. The outbreak waned during the unusually dry winter. Using a Monte Carlo test we investigated the hypothesis that rainy weather conveyed increased risk of dengue virus infection among tourists. Results confirmed the hypothesis. As it is unclear whether the outbreak is over, upkeep and emphasis on mosquito avoidance on rainy days may help residents and tourists reduce infection risk.
Using Educational Games to Engage Students in Veterinary Basic Sciences
Authors: Buur Jennifer L. , Schmidt Peggy L. , Barr Margaret C.
Published: May 2013

Educational games are an example of an active learning teaching technique based on Kolb's learning cycle. We have designed multiple games to provide concrete experiences for social groups of learners in the basic sciences. “Antimicrobial Set” is a card game that illustrates global patterns in antimicrobial therapy. “SHOCK!” is a card game designed to enhance student understanding of the four types of hypersensitivity reactions. After each game is played, students undergo a structured debriefing session with faculty members to further enhance their self-reflective skills. “Foodborne Outbreak Clue” utilizes the famous Parker Brothers® board game as a means to practice skills associated with outbreak investigation and risk assessment. This game is used as a review activity and fun application of epidemiologic concepts. Anecdotal feedback from students suggests that they enjoyed the activities. Games such as these can be easily implemented in large- or small-group settings and can be adapted to other disciplines as needed.
Problem-Based Learning: Facilitating Multiple Small Teams in a Large Group Setting
Authors: Hyams Jennifer H. , Raidal Sharanne L.
Published: May 2013

Problem-based learning (PBL) is often described as resource demanding due to the high staff-to-student ratio required in a traditional PBL tutorial class where there is commonly one facilitator to every 5–16 students. The veterinary science program at Charles Sturt University, Australia, has developed a method of group facilitation which readily allows one or two staff members to facilitate up to 30 students at any one time while maintaining the benefits of a small PBL team of six students. Multi-team facilitation affords obvious financial and logistic advantages, but there are also important pedagogical benefits derived from uniform facilitation across multiple groups, enhanced discussion and debate between groups, and the development of self-facilitation skills in students. There are few disadvantages to the roaming facilitator model, provided that several requirements are addressed. These requirements include a suitable venue, large whiteboards, a structured approach to support student engagement with each disclosure, a detailed facilitator guide, and an open, collaborative, and communicative environment.
Adaptive Global Carbon Monoxide Kinetic Mechanism over Platinum/Alumina Catalysts
Authors: Depcik Christopher , Loya Sudarshan , Srinivasan Anand , Wentworth Travis , Stagg-Williams Susan
Published: May 2013

Carbon monoxide (CO) oxidation is one of the more widely researched mechanisms given its pertinence across many industrial platforms. Because of this, ample information exists as to the detailed reaction steps in its mechanism. While detailed kinetic mechanisms are more accurate and can be written as a function of catalytic material on the surface, global mechanisms are more widely used because of their computational efficiency advantage. This paper merges the theory behind detailed kinetics into a global kinetic model for the singular CO oxidation reaction while formulating expressions that adapt to catalyst properties on the surface such as dispersion and precious metal loading. Results illustrate that the model is able to predict the light-off and extinction temperatures during a hysteresis experiment as a function of different inlet CO concentrations and precious metal dispersion.
MicroRNAs and Molecular Mechanisms of Neurodegeneration
Authors: Bicchi Ilaria , Morena Francesco , Montesano Simona , Polidoro Mario , Martino Sabata
Published: May 2013

During the last few years microRNAs (miRNAs) have emerged as key mediators of post-transcriptional and epigenetic regulation of gene expression. MiRNAs targets, identified through gene expression profiling and studies in animal models, depict a scenario where miRNAs are fine-tuning metabolic pathways and genetic networks in both plants and animals. MiRNAs have shown to be differentially expressed in brain areas and alterations of miRNAs homeostasis have been recently correlated to pathological conditions of the nervous system, such as cancer and neurodegeneration. Here, we review and discuss the most recent insights into the involvement of miRNAs in the neurodegenerative mechanisms and their correlation with significant neurodegenerative disorders.
Preservation and Recycling of Crust during Accretionary and Collisional Phases of Proterozoic Orogens: A Bumpy Road from Nuna to Rodinia
Authors: Condie Kent
Published: May 2013

Zircon age peaks at 2100–1650 and 1200–1000 Ma correlate with craton collisions in the growth of supercontinents Nuna and Rodinia, respectively, with a time interval between collisions mostly <50 Myr (range 0–250 Myr). Collisional orogens are two types: those with subduction durations <500 Myr and those ≥500 Myr. The latter group comprises orogens with long-lived accretionary stages between Nuna and Rodinia assemblies. Neither orogen age nor duration of either subduction or collision correlates with the volume of orogen preserved. Most rocks preserved date to the pre-collisional, subduction (ocean-basin closing) stage and not to the collisional stage. The most widely preserved tectonic setting in Proterozoic orogens is the continental arc (10%–90%, mean 60%), with oceanic tectonic settings (oceanic crust, arcs, islands and plateaus, serpentinites, pelagic sediments) comprising <20% and mostly <10%. Reworked components comprise 20%–80% (mean 32%) and microcratons comprise a minor but poorly known fraction. Nd and Hf isotopic data indicate that Proterozoic orogens contain from 10% to 60% of juvenile crust (mean 36%) and 40%–75% reworked crust (mean 64%). Neither the fraction nor the rate of preservation of juvenile crust is related to the collision age nor to the duration of subduction. Regardless of the duration of subduction, the amount of juvenile crust preserved reaches a maximum of about 60%, and 37% of the volume of juvenile continental crust preserved between 2000 and 1000 Ma was produced in the Great Proterozoic Accretionary Orogen (GPAO). Pronounced minima occur in frequency of zircon ages of rocks preserved in the GPAO; with minima at 1600–1500 Ma in Laurentia; 1700–1600 Ma in Amazonia; and 1750–1700 Ma in Baltica. If these minima are due to subduction erosion and delamination as in the Andes in the last 250 Myr; approximately one third of the volume of the Laurentian part of the GPAO could have been recycled into the mantle between 1500 and 1250 Ma. This may have enriched the mantle wedge in incompatible elements and water leading to the production of felsic magmas responsible for the widespread granite-rhyolite province of this age. A rapid decrease in global Nd and in detrital zircon Hf model ages between about 1600 and 1250 Ma could reflect an increase in recycling rate of juvenile crust into the mantle; possibly in response to partial fragmentation of Nuna.
Silicon Era of Carbon-Based Life: Application of Genomics and Bioinformatics in Crop Stress Research
Authors: Li Man-Wah , Qi Xinpeng , Ni Meng , Lam Hon-Ming
Published: May 2013

Abiotic and biotic stresses lead to massive reprogramming of different life processes and are the major limiting factors hampering crop productivity. Omics-based research platforms allow for a holistic and comprehensive survey on crop stress responses and hence may bring forth better crop improvement strategies. Since high-throughput approaches generate considerable amounts of data, bioinformatics tools will play an essential role in storing, retrieving, sharing, processing, and analyzing them. Genomic and functional genomic studies in crops still lag far behind similar studies in humans and other animals. In this review, we summarize some useful genomics and bioinformatics resources available to crop scientists. In addition, we also discuss the major challenges and advancements in the “-omics” studies, with an emphasis on their possible impacts on crop stress research and crop improvement.
Multiple Estimation Architecture in Discrete-Time Adaptive Mixing Control
Authors: Baldi Simone
Published: May 2013

Adaptive mixing control (AMC) is a recently developed control scheme for uncertain plants, where the control action coming from a bank of precomputed controller is mixed based on the parameter estimates generated by an on-line parameter estimator. Even if the stability of the control scheme, also in the presence of modeling errors and disturbances, has been shown analytically, its transient performance might be sensitive to the initial conditions of the parameter estimator. In particular, for some initial conditions, transient oscillations may not be acceptable in practical applications. In order to account for such a possible phenomenon and to improve the learning capability of the adaptive scheme, in this paper a new mixing architecture is developed, involving the use of parallel parameter estimators, or multi-estimators, each one working on a small subset of the uncertainty set. A supervisory logic, using performance signals based on the past and present estimation error, selects the parameter estimate to determine the mixing of the controllers. The stability and robustness properties of the resulting approach, referred to as multi-estimator adaptive mixing control (Multi-AMC), are analytically established. Besides, extensive simulations demonstrate that the scheme improves the transient performance of the original AMC with a single estimator. The control scheme and the analysis are carried out in a discrete-time framework, for easier implementation of the method in digital control.
Fucoxanthin from Undaria pinnatifida: Photostability and Coextractive Effects
Authors: Piovan Anna , Seraglia Roberta , Bresin Bruno , Caniato Rosy , Filippini Raffaella
Published: May 2013

Fucoxanthin is one of the most abundant carotenoids and possesses a number of beneficial medicinal qualities which include its anti-oxidant, anti-obesity and anti-cancer properties. In this study, the photostability of fucoxanthin in extracts with different chemical profiles was studied. The extracts were obtained from Undaria pinnatifida, a seaweed rich in this carotenoid, using conventional liquid solvent extraction procedures and the QuEChERS method. All the extracts contained all-trans-fucoxanthin as the major compound. Conventional procedures produced a fucoxanthin purity of lower than 50%, whereas after liquid-liquid partition, PSA cleanup, and PSA and GCB cleanup (QuEChERS method) fucoxanthin purity increased to 70%, 86%, and 94%, respectively. Although in the acetone extract the initial content of fucoxanthin was the highest, results demonstrate that coextractives play an important role in enhancing the rate of photodegradation. After light exposure, the conventional extracts lost around 90% of the initial fucoxanthin content. On the other hand, the extracts obtained by the QuEChERS method showed significantly higher light stability than the conventional extracts. These results suggest that the QuEChERS method could be used and further improved to obtain more purified and stable extracts for fucoxanthin from U. pinnatifida.
Macular Pigment and Its Contribution to Vision
Authors: Loskutova Ekaterina , Nolan John , Howard Alan , Beatty Stephen
Published: May 2013

Three dietary carotenoids, lutein (L), zeaxanthin (Z) and meso-zeaxanthin (MZ) accumulate at the central retina (macula), where they are collectively referred to as macular pigment (MP). MP’s pre-receptoral absorption of blue light and consequential attenuation of the effects of chromatic aberration and light scatter are important for optimal visual function. Furthermore, antioxidant activity of MP’s constituent carotenoids and the same blue light-filtering properties underlie the rationale for its putative protective role for age-related macular degeneration (AMD). Supplementation with L, Z and MZ augments MP and enhances visual performance in diseased and non-diseased eyes, and may reduce risk of AMD development and/or progression.
Phorbol Ester Modulation of Ca2+ Channels Mediates Nociceptive Transmission in Dorsal Horn Neurones
Authors: Yang Li , Topia Iqbal , Schneider Toni , Stephens Gary
Published: May 2013

Phorbol esters are analogues of diacylglycerol which activate C1 domain proteins, such as protein kinase C (PKC). Phorbol ester/PKC pathways have been proposed as potential therapeutic targets for chronic pain states, potentially by phosphorylating proteins involved in nociception, such as voltage-dependent Ca2+ channels (VDCCs). In this brief report, we investigate the potential involvement of CaV2 VDCC subtypes in functional effects of the phorbol ester, phorbol 12-myristate 13-acetate (PMA) on nociceptive transmission in the spinal cord. Effects of PMA and of selective pharmacological blockers of CaV2 VDCC subtypes on nociceptive transmission at laminae II dorsal horn neurones were examined in mouse spinal cord slices. Experiments were extended to CaV2.3(−/−) mice to complement pharmacological studies. PMA increased the mean frequency of spontaneous postsynaptic currents (sPSCs) in dorsal horn neurones, without an effect on event amplitude or half-width. sPSC frequency was reduced by selective VDCC blockers, w-agatoxin-IVA (AgTX; CaV2.1), w-conotoxin-GVIA (CTX; CaV2.2) or SNX-482 (CaV2.3). PMA effects were attenuated in the presence of each VDCC blocker and, also, in CaV2.3(−/−) mice. These initial data demonstrate that PMA increases nociceptive transmission at dorsal horn neurones via actions on different CaV2 subtypes suggesting potential anti-nociceptive targets in this system.
Understanding the “Black Box” of Employer Decisions about Health Insurance Benefits: The Case of Depression Products
Authors: Rost Kathryn , Papadopoulos Airia , Wang Su , Marshall Donna
Published: May 2013

In a randomized trial of two interventions on employer health benefit decision-making, 156 employers in the evidence-based (EB) condition attended a two hour presentation reviewing scientific evidence demonstrating depression products that increase high quality treatment of depression in the workforce provide the employer a return on investment. One-hundred sixty-nine employers participating in the usual care (UC) condition attended a similar length presentation reviewing scientific evidence supporting healthcare effectiveness data and information set (HEDIS) monitoring. This study described the decision-making process in 264 (81.2%) employers completing 12 month follow-up. The EB intervention did not increase the proportion of employers who discussed depression products with others in the company (29.2% versus 32.1%, p > 0.10), but it did significantly influence the content of the discussions that occurred. Discussion in EB companies promoted the capacity of a depression product to realize a return on investment (18.4% versus 4.7%, p = 0.05) and to improve productivity (47.4% versus 25.6%, p = 0.06) more often than discussions in UC companies. Almost half of EB and UC employers reported that return on investment has a large impact on health benefit decision-making. These results demonstrate the difficulty of influencing employer decisions about health benefits using group presentations.
Impact de l'implantation des dispensaires et de l'activité des « passants » et des vendeurs de médicaments chinois sur la maladie djékwasô en pays Gouro (Côte d'Ivoire)
Authors: Haxaire Claudie
Published: May 2013

À l’époque où les dispensaires de soins de santé rurale dotés de médicaments génériques s’implantaient dans la région de Zuénoula (RCI), le système de soins de santé se voyait doté de nouveaux acteurs, à savoir les vendeurs ambulants de médicaments « chinois », qui concurrençaient les « passants » de circuits alternatifs. Une enquête longitudinale dans trois villages gouro a permis d’analyser l’impact de l’accessibilité de ces médicaments et de leur efficacité perçue sur le redécoupage de l’ensemble djekwasô, entité nosologique populaire qui peut recouvrir le paludisme, diverses fièvres, les hépatites voire le sida. Alors que ces différents circuits de commercialisation distribuaient des médicaments industriels de mêmes formules, qui auraient pu prendre une connotation différente selon les circuits, ce furent au contraire les circuits qui se spécialisèrent en sélectionnant les médicaments selon leur efficacité perçue sur les variantes de l’ensemble djekwasô qu’ils prétendaient traiter.
La revue Dialogue et son histoire du n˚ 100 au n˚ 200
Authors: Dupré La Tour Monique
Published: May 2013

Ancien membre actif de la revue Dialogue , l’auteur de ce texte revient sur l’évolution de cette dernière au cours des cent derniers numéros. Après avoir présenté le fonctionnement interne de la revue et rappelé son approche pluridisciplinaire, elle propose, à partir de l’observation des titres des articles et des intitulés des numéros, de faire ressortir les problématiques qui émergent, parfois en force, et parfois disparaissent au cours des vingt-cinq dernières années, reflétant les évolutions et préoccupations sociétales.
Changements collectifs, continuité/discontinuité psychique
Authors: Robert Philippe
Published: May 2013

La revue Dialogue a toujours tenté des ouvertures et des échanges épistémologiques. Chaque clinicien et chaque chercheur s’inscrit dans une filiation qui doit soutenir sa cohérence de pensée sans l’enfermer dans un dogmatisme. Tout en gardant sa référence princeps à l’Inconscient, l’analyse a évolué dans sa confrontation à l’extension de ses champs cliniques. Les couples et les familles ont eux-mêmes changé – tout du moins structurellement – en lien avec les modifications collectives. Tout ceci nécessite des échanges rigoureux ne devant céder ni à la facilité, ni à la confusion. Les effets des changements interrogent également les aspects techniques dans la clinique avec les couples et les familles.
Dans les ténèbres de l'incestualité
Authors: Payen Françoise
Published: May 2013

Ce travail rend compte d’une recherche d’un groupe de l’ IPSYC (IPSYC : Institut de psychanalyse de couple) autour de la conflictualité psychique conjugale avec comme question corollaire : comment le groupe formé par le couple et le clinicien peut-il l’appréhender et la traiter ? La conflictualité psychique conjugale, distincte de la conflictualité interne du sujet, n’est pas non plus la résonance entre les deux conflictualités psychiques de chacun des partenaires, mais une production psychique couplale. Elle se manifeste au sein du néogroupe formé par le clinicien et le couple par l’apparition d’imagos menaçantes. L’auteur a fait l’hypothèse que, dans le travail analytique avec un couple, ce néogroupe permet le passage d’un stade de la groupalité à un autre, entraînant la chute des imagos menaçantes.
Mariage pour tous et homoparentalité
Authors: Théry Irène
Published: May 2013

Pourquoi les homosexuels n’avaient-ils pas, jadis, l’idée de demander à se marier alors que le souci d’égalité entre tous les couples, la revendication à être « comme les autres » est manifeste aujourd’hui ? Il est important de situer les interrogations et changements actuels dans le temps long de l’histoire. L’article montre dans quelle mesure les fondements du mariage et de la filiation se sont modifiés, désormais la filiation ne repose plus sur le socle du mariage. L’évolution des attitudes des homosexuels est en lien direct avec ces transformations.
Famille et handicap : mutations dans les pratiques
Authors: Gargiulo Marcela , Scelles Régine
Published: May 2013

Après une présentation de l’évolution des manières de concevoir l’aide psychologique à apporter à la famille dans le cas spécifique de maladies d’origine génétique, l’article montre que tous les membres de la famille, y compris les enfants, sont conduits à une réflexion sur les mystères de l’origine, les inégalités biologiques, le risque réel, imaginaire et fantasmatique encouru. Cette réflexion concerne les groupes et sous-groupes que la famille forme en y incluant l’ensemble de la chaîne des générations. Est soulignée la difficulté des adultes, parents et professionnels, à permettre à l’enfant et à la fratrie d’exprimer ses interrogations concernant l’origine génétique du handicap et ses avatars.
La reconfiguration de la socialisation précoce
Authors: Neyrand Gérard
Published: May 2013

Notre époque de profonde transformation des rapports familiaux et éducatifs voit certaines instances de socialisation du jeune enfant prendre une importance croissante : les médias, les modes d’accueil, les pairs. Le parentalisme inhérent au dispositif de parentalité contemporain a tendance à masquer l’importance de cette fonction partagée de coéducation des enfants. Pourtant celle-ci constitue encore plus profondément une cosocialisation, qu’il conviendrait de mieux connaître pour répondre aux objectifs affichés de la démocratie d’autonomisation et d’épanouissement des individus.
On Deficits and Unemployment
Authors: Eaton Jonathan , Kortum Samuel , Neiman Brent
Published: May 2013

Entre 2007 et 2011 le chômage s’est accru notablement dans la plupart des pays européens. Durant la même période, les déficits extérieurs de nombreux pays européens se sont fortement réduits. Nous utilisons un modèle d’équilibre général, de type ricardien et reposant sur des rigidités salariales, couvrant trente-quatre pays, pour analyser la relation entre les ajustements extérieurs, les pnb relatifs et le chômage durant cette période. Notre analyse permet de décomposer les mécanismes d’ajustement par le biais du chômage et de la baisse des salaires. Le chômage a joué le rôle le plus important, mais les baisses du pnb nominal se sont mieux reflétées dans le pnb réel. JEL Code: F16, F32
Régimes de change et commerce Chine-Afrique
Authors: Guillaumont Jeanneney Sylviane , Hua Ping
Published: May 2013

Cet article étudie l’influence des régimes de change sur la croissance spectaculaire du commerce entre la Chine et l’Afrique au sud du Sahara. Un modèle de gravité augmenté des taux de change réels montre que les exportations de biens manufacturés de la Chine sont stimulées par la dépréciation réelle du renminbi à l’égard de nombreuses monnaies africaines, alors que ses importations de produits primaires y sont insensibles. Ainsi la concurrence chinoise risque d’handicaper le développement de l’industrie africaine dans les pays qui connaissent une appréciation réelle de leur monnaie vis-à-vis du renminbi, soit du fait du rattachement de celle-ci à l’euro, soit du fait de l’ampleur de leurs exportations de produits primaires, elles-mêmes stimulées par la demande chinoise.
Potential Therapies for Food Allergy: A Review
Authors: Kattan Jacob D. , Wang Julie
Published: May 2013

CME Educational Objectives

1.

Understand the numerous food allergy therapies, both allergen specific and non-specific, currently under investigation.

2.

Discuss the safety concerns that accompany potential food allergy treatments.

3.

Appreciate the difference between desensitization and tolerance as they relate to food allergy.

Food allergy is a widespread problem that has been increasing in prevalence in recent years. Avoidance of food allergens is difficult. Food allergic reactions are common and can be severe. Unfortunately, there is little in the way of therapies for food allergy, and strict allergen avoidance remains the standard of care. Several therapeutic approaches are currently being investigated, including subcutaneous, oral, and sublingual immunotherapy, anti-immunoglobulin E therapy, and traditional Chinese medicine. Although results thus far show promise for several of these strategies, further studies are needed to evaluate the safety, efficacy, and long-term outcomes before any food allergy therapies currently under investigation are ready for widespread use in clinical practice.
Primary Open-Angle Glaucoma
Authors: Yumori Jasmine W. , Cadogan Mary P.
Published: May 2013

Glaucoma is an optic neuropathy that is usually associated with an elevated intraocular pressure. Primary open-angle glaucoma (POAG) is the most common type of glaucoma and is progressive and bilateral but typically asymmetric in patients. Studies have shown that reducing intraocular pressure reduces the risk of vision loss. In the United States, medical intervention by means of prescription eye drops is the initial line of treatment. Nurses play an important role in educating individuals, particularly older adults, about the importance of routine eye care to earlier diagnose, treat, and adequately manage eye diseases such as POAG.
Individualized Skills Training Program for Community-Dwelling Adults with Mild Alzheimer’s Disease
Authors: Curtin Alicia J.
Published: May 2013

The increasing incidence of Alzheimer’s disease (AD) has created an enormous challenge to nurses. Nonpharmacological interventions that promote functional independence at home are vital to improving quality of life for individuals with AD and their caregivers. The purpose of this study was to explore the effectiveness of a skills training program for individuals with mild AD in the home setting. Although none of the participants achieved total independence in performing the meal task, all decreased their need for task prompting. The goal for this population may be to preserve and encourage a more functional state rather than to achieve total independence.
Feeding strategy assessment through fatty acid profiles in muscles of adult sea lampreys from the western Iberian coast
Authors: Lança Maria João , Machado Maria , Ferreira Rui , Alves-Pereira Isabel , Ruivo Quintella Bernardo , Raposo de Almeida Pedro
Published: May 2013

The fatty acid signature of sea lamprey Petromyzon marinus (L.) muscle was used as a tool to detect feeding strategies used during the parasitic marine trophic phase of the species. Adult sea lampreys were collected near the mouth of six Portuguese rivers (Minho, Lima, Douro, Vouga, Mondego and Tagus) and muscle fatty acid profile was characterized. The analysis of fatty acid composition of muscle neutral lipids showed the formation of two groups, indicating that two feeding strategies may have been used by sea lampreys during the parasitic phase, based on the availability of ω-3 and ω-6 PUFA and on evidence of phytoplankton/zooplankton and bacterial detritus contribution in the sea lamprey host preferences. Two distinct lipid profiles were observed, probably related to two different trophic approaches, one typical of a top predator of a marine food web with a planktonic support, and the other much more diverse, including the same planktonic markers, together with biochemical clues that probably resulted from a parasitic phase that directly targeted fish that consumed detritus and benthic algae and/or fish from a food web with a detritivorous base.
Presentación
Authors: Tapia Ladino Marcela
Published: May 2013

Presentación
VIDA FAMILIAR TRANSNACIONAL EN INMIGRANTES DE MÉXICO Y REPÚBLICA DOMINICANA EN DOS CONTEXTOS DE RECEPCIÓN
Authors: Ariza Marina
Published: May 2013

Con base en una serie de entrevistas a profundidad realizadas con trabajadoras inmigrantes de México y República Dominicana en dos ciudades de inmigración –Nueva York para las mexicanas y Madrid para las dominicanas–, se exploran las pautas de interacciónen tres dimensiones centrales de la vida familiar: la reproducción doméstica, lamaternidad y el cuidado, y la afectividad. A pesar de las semejanzas en los patrones de interacción, emergen algunas diferencias en virtud de las disímiles estructuras familiares de los países de origen, las pautas de la migración internacional y las políticas migratorias de España y Estados Unidos como contextos de recepción.
ARTICULACIONES DE LA EXCLUSIÓN. LA POLÍTICA DE ATENCIÓN A PROSTITUTAS INMIGRANTES EN MADRID
Authors: Mayorga Claudia
Published: May 2013

El presente artículo analiza las concepciones acerca de la inmigración y prostitución femeninapresentes en las sociedades contemporáneas globalizadas. En un momento cuando el aumento de los flujos migratorios femeninos hacia países de la Unión Europea escreciente, la noción de tráfico de mujeres ha sido utilizada como marco interpretativo exclusivo para análisis de la relación entre inmigración femenina y prostitución, y se registranposiciones racistas y xenófobas hacia colectivos de mujeres inmigrantes. A partir de los discursos y prácticas de tres organizaciones no gubernamentales en la ciudad deMadrid, que atienden al colectivo de inmigrantes extracomunitarias que actúan en la prostitución, es posible identificar aspectos patriarcales y coloniales que fundamentanposiciones político-institucionales diversas, indicando la complejidad presente en la articulación entre migración y prostitución en el contexto contemporáneo.
MIGRACIÓN Y TRANSICIÓN: HIJOS DE INMIGRANTES DE ORIGEN LATINOAMERICANO EN SU TRANSICIÓN DE LA ESCUELA AL TRABAJO EN CHILE
Authors: Hein Kerstin
Published: May 2013

Se presentan los principales resultados de un estudio cuyo objetivo fue comprender la forma en que hijos de inmigrantes de origen latinoamericano en Chile viven, entienden y manejan su transición de la escuela al trabajo. Con este propósito se realizaron entrevistas biográficas narrativas y evaluaciones cualitativas de las redes sociales de 13 hijos de extranjeros de origen latinoamericano en Chile. Los jóvenes fueron contactados por primera vez durante su último año de educación secundaria, y entrevistados por segunda vez un año después de haber abandonado el sistema escolar. Entre los resultados que se discuten se encuentra el proceso de migración de los entrevistados, su integración cultural en el país y su percepción de la distancia cultural. También se aborda la integración social y experiencias de discriminación que afectan a los jóvenes en el contexto escolar. Finalmente se presenta la evolución de todos estos aspectos un año después de que los participantes han egresado de la enseñanza media.
Conservative Multimodal Management of a Primitive Neuroectodermal Tumor of the Thyroid
Authors: Natale Romain , Thariat Juliette , Vedrine Pierre Olivier , Bozec Alex , Peyrottes Isabelle , Marcy Pierre Yves , Haudebourg Juliette , Pedeutour Florence , Saâda Esma , Thyss Antoine
Published: May 2013

Primitive neuroectodermal tumors (PNET) represent 1% of sarcomas. Head and neck peripheral PNETs have an intermediate prognosis between abdominopelvic disease and extremities. We here report the case of a 40-year old male who presented with primitive neuroectodermal tumor of the thyroid and was treated by multimodal treatment, including surgery, chemotherapy and intermediate dose radiotherapy. The patient is alive and fit with a functional larynx at 27 months. Multimodal treatments yield five-year survival rates of about 60%. Major drug regimens use vincristine, doxorubicin, ifosfamide or cyclophosphamide, dactinomycin and/or etoposide. Complete surgical excision is undertaken whenever possible to improve long-term survival. However, the relative radiosensitivity of tumors of the Ewing family, suggest multimodal treatment including adjuvant conformal radiotherapy in case of positive margins or poor response to chemotherapy rather than resection with 2-3 cm margins, which would imply laryngeal sacrifice for thyroid tumors. The role of expert rare tumor networks is crucial for optimal decision-making and management of such rare tumors on a case by case basis.
Optimal and Near Optimal Configurations on Lattices and Manifolds
Authors: Bachoc Christine , Grabner Peter , Saff Edward B. , Schürmann Achill
Published: May 2013

Optimal configurations of points arise in many contexts, for example classical ground states for interacting particle systems, Euclidean packings of convex bodies, as well as minimal discrete and continuous energy problems for general kernels. Relevant questions in this area include the understanding of asymptotic optimal configurations, of lattice and periodic configurations, the development of algorithmic constructions of near optimal configurations, and the application of methods in convex optimization such as linear and semidefinite programming.
Rough Paths and PDEs
Authors: Crisan Dan , Friz Peter K. , Gubinelli Massimiliano
Published: May 2013

The purpose of the Oberwolfach workshop ”Rough Paths and PDEs” was to bring together these researchers, both young and senior, with the aim to promote progress in rough path theory, the connections with partial differential equations and its applications to numerical methods.
Komplexe Analysis
Authors: Demailly Jean-Pierre , Hulek Klaus , Peternell Thomas
Published: May 2013

The aim of this workshop was to discuss recent developments in several complex variables and complex geometry. Special emphasis was put on the interaction of analytic and algebraic methods. Topics included Kähler geometry, Ricci-flat manifolds, moduli theory and themes related to the minimal model program.
Topologie
Authors: Schick Thomas , Teichner Peter , Wahl Nathalie , Weiss Michael
Published: May 2013

The Oberwolfach conference “Topologie” is one of the few occasions where researchers from many different areas in algebraic and geometric topology are able to meet and exchange ideas. Accordingly, the program covered a wide range of new developments in such fields as classification of manifolds, isomorphism conjectures, geometric topology, and homotopy theory. More specifically, we discussed progress on problems such as the Farrell-Jones conjecture, higher dimensional analogues of Harer’s homological stability of automorphism groups of manifolds and new algebraic concepts for equivariant spectra, to mention just a few subjects. One of the highlights was a series of four talks on new methods and results about the Farrell-Jones conjecture by Arthur Bartels and Wolfgang Lück.
Scrub Typhus and Cerebrovascular Injury: A Phenomenon of Delayed Treatment?
Authors: Chung Jong-Hoon , Yun Na-Ra , Kim Dong-Min , Lee Ji-Woon , Yoon Sung Ho , Kim Seok-Won
Published: May 2013

Three patients diagnosed with scrub typhus through serology and polymerase chain reaction tests, experienced delayed administration of effective antibiotics after the appearance of symptoms, presented with subdural hemorrhage, intracerebral hemorrhage, or cerebral infarction in the late acute phase. Orientia tsutsugamushi should be considered as a causal or provoking factor for cerebrovascular accidents in regions where scrub typhus is endemic, especially in those who receive delayed treatment.
Downstream Research Joint Venture with Upstream Market Power
Authors: Manasakis Constantine , Petrakis Emmanuel , Zikos‡ Vasileios
Published: May 2013

In a vertically related industry, we examine the downstream firms' incentives to invest in cost‐reducing Research and Development (R&D), and to form a Research Joint Venture (RJV), under two alternative structures of input supply: exclusive vertical relations and a single supplier. In contrast to the “hold‐up” argument, in which downstream firms invest non‐cooperatively and spillovers are low, R&D investments are higher under a single supplier than under competing vertical chains. Downstream firms' incentives to form a RJV are also stronger in the former case than they are in the latter. We identify conditions under which an RJV is beneficial for society. Integrated innovation and competition policies are also discussed.
A Primer for New Teachers of Economics
Authors: Sheridan Brandon J. , Hoyt Gail , Imazeki Jennifer
Published: May 2013

In many economics programs, both graduate students and new assistant professors are thrown into the classroom without guidance, with the potential for negative ramifications that can last throughout their careers as teachers. This article is a primer in which we offer unique insights into useful methods and practices for new teachers in the economics profession. We discuss organizational and logistical issues that new teachers must consider and then offer our advice on specific pedagogical tools and techniques. Following the growing literature on the benefits of student‐centered and interactive instruction, we focus on ways instructors can move away from the traditional “chalk and talk” approach. We organize and present these alternative pedagogies in terms of their level of complexity and time required. We conclude with suggestions and resources for the continued growth and development of new teachers in economics.
The Influence of Corneal Volume in Surgical Planning: Insights for a New Parameter for the Ferrara Ring Nomogram
Authors: Torquetti Leonardo , Dias Wagner Gomes
Published: May 2013

Purpose

To evaluate the corneal volume (CV) before and after Ferrara intrastromal corneal ring segments (ICRS) implantation and its influence in clinical outcomes in keratoconus patients.

Materials and methods

A total of 77 eyes of 42 keratoconus patients consecutively implanted with the Ferrara ICRS were evaluated with a Pentacam (Oculus Optikgerate GmbH). The following parameters were obtained: Anterior corneal asphericity (Q), CV and thinnest corneal thickness (TCT). The inter-relation between Q and CV was evaluated.

Results

In patients with CV inside two standard deviation (SD: 53.51-60.65) of the mean CV, the postoperative asphericity values roughly agreed with expected asphericity values. In patients with CV outside two SD intervals (<53.51 and >60.65) of the mean CV, the postoperative asphericity values did not agreed with expected asphericity values. Corneas with high volumes (>60.65) had less change of asphericity than corneas with low volumes.

Conclusion

The CV is a new parameter, to be better studied, as it seems to be important in ICRS selection. Corneas with high volumes may require more tissue to get flattened and properly reshaped.

How to cite this article

Torquetti L, Ferrara G, Dias WG, Ferrara P. The Influence of Corneal Volume in Surgical Planning: Insights for a New Parameter for the Ferrara Ring Nomogram. Int J Kerat Ect Cor Dis 2013;2(1):12-15.