bluuebunny/crossref_metadata_2025 huggingface dataset:
Docking Ligands into Flexible and Solvated Macromolecules. 8. Forming New Bonds – Challenges and Opportunities.
Authors: Moitessier Nicolas , Labarre Anne , Stille Julia , Patrascu Mihai Burai , Martins Andrew , Pottel Joshua
Published: May 2021

Over the years, structure-based design programs and specifically docking small molecules to proteins have become prominent in drug discovery. However, many of these computational tools have been developed to primarily dock enzyme inhibitors (and ligand to other protein classes) relying heavily on hydrogen bonds, electrostatic and hydrophobic interactions. In reality, many drug targets either feature metal ions, can be targeted covalently, or are simply not even proteins (e.g., nucleic acids). Herein, we describe several new features that we have implemented into FITTED to broaden its applicability to a wide range of covalent enzyme inhibitors, and to metalloenzymes, where metal coordination is essential for drug binding. We also report new datasets that were essential demonstrate areas of success and those where additional efforts are required. This resource could be used by other program developers to assess their own
Promotion of C-S Bond Scission over Solid Catalytic Sulfides by Aromatics and Nitrogen Heterocycles
Authors: Morales-Valencia Edgar M. , Vargas-Montañez Omar J. , Monroy-García Pablo Alexander , Avendaño Lina , Quintero-Quintero Eduard Arley , Elder-Bueno Camila , Santiago Guerrero Aidé Yojana , Baldovino Medrano Víctor Gabriel
Published: May 2021

The competitive adsorption of aromatics and nitrogen heterocycles on the active sites of solid catalytic sulfides (Ni(Co)-MoS2 dispersed over oxidic carriers) typically causes inhibitory effects during the hydropurification of sulfur heterocycles. Contrary to this typical behavior, we report herein that it is possible to promote the scission of the C-S bond of refractory dibenzothiophene by co?feeding the above compounds during hydropurification over a conventional Ni-MoS2/Al2O3 catalyst. Particularly, we prove that at temperatures between 240 and 300°C and concentrations of dibenzothiophene between 1.0 and 3.7 wt.%, the desulfurization of dibenzothiophene is promoted by increasing its conversion up to 370% when either naphthalene, indole, or quinoline are co-fed to the reaction system. The work highlights the following: (i) lower temperatures and higher concentrations of the sulfur heterocycle enhanced the cleavage of the C-S bond from dibenzothiophene; (ii) it is possible to promote hydropurification reactions regardless of the nature of the of co-reactants; namely: a fused aromatic ring -naphthalene-, or a fused nitrogen heterocycle with a lone pair belonging to the pi-system -quinoline- or not -indole-.
De Novo Design with Deep Generative Models Based on 3D Similarity Scoring
Authors: Papadopoulos Kostas , Giblin Kathryn A. , Janet Jon Paul , Patronov Atanas , Engkvist Ola
Published: May 2021

We have demonstrated the utility of a 3D shape and pharmacophore similarity scoring component in molecular design with a deep generative model trained with reinforcement learning. Using Dopamine receptor type 2 (DRD2) as an example and its antagonist haloperidol 1 as a starting point in a ligand based design context, we have shown in a retrospective study that a 3D similarity enabled generative model can discover new leads in the absence of any other information. It can be efficiently used for scaffold hopping and generation of novel series. 3D similarity based models were compared against 2D QSAR based, indicating a significant degree of orthogonality of the generated outputs and with the former having a more diverse output. In addition, when the two scoring components are combined together for training of the generative model, it results in more efficient exploration of desirable chemical space compared to the individual components.
Edukasi teknologi hidroponik untuk pemberdayaan lahan pekarangan
Authors: Ismail Ismail , Syam Agus
Published: May 2021

The acceleration of diversification of food consumption based on local resources has become a government policy. One form of the implementation of the policy is the optimization of the use of the yard. To optimize the function of the yard as a source of vegetable food, training in hydroponic technology education activities has been conducted with community partners in the village of Tunikamaseang, Maros Regency. The Community Partnership Program is carried out with the aim of increasing: 1) hydroponic system vegetable farming techniques and skills, 2) increasing family food security. The method used is the reflection, demonstration and practice of hydroponic system cultivation, with the Participatory Rural Appraisal approach. The result of devotion achieved is an increase in partner's knowledge and skills in the cultivation of the hydroponic system. The output of this activity is the vegetable cultivation model of the hydroponic system.
Pelatihan praktik melukis teknik fresco bagi siswa Kelas X di Sekolah Menengah Atas Negeri 14 Makassar
Authors: Husain Muh. Saleh , Maida Andi Nur , Subiantoro Benny
Published: May 2021

The material of the learning process of the theory of fine arts education and the practicum of fine arts education, whose behavior to directed at the process of serving the concepts of aesthetic concepts, creativity and work, adjusted to the level of ability of the students themselves. The connection in this case, to avoid the passivity of students during the learning process of art education, through the presentation of educational media implemented by the teacher will be a motivation for creative thinking to apply freedom to express their feelings and realize real work increating works of art in accordance with the assignment of structured subject matter from the teacher. The tendency to words increasing teaching in fine arts education will benefit from being presented informal academic instituions that are applied in Makassar public High School 14, regarding the learning process in an innovative direction, both in the form of basic theoretical offerings and the practice of creating fine art is pretty much marked through a form of teaching process that gives room for creativity, explanation, learning to work on Fresco techniques, which of course begins with the practice of learning to draw sketches that are applied to Makassar14 Senior High School students, so students will experience a change from not knowing to being know, through growth in attitudes and growth in thinking more creative and intelligent.
Penggunaan lemari pengasapan ikan untuk meningkatkan produksi pada industri rumah tangga di Kabupaten Pulau Morotai
Authors: Tjiroso Bambang , Nur Rinto M. , Bustan Ariestha W.
Published: May 2021

One processed fish product that is favored by many people on Morotai Island is smoked fish. Although much popular, the smoked fish home industry on Morotai Island does not routinely produce smoked fish every day. Smoked fish processing still uses conventional equipments. The equipment which is open makes it difficult for partners to maximize the use of combustion fumes to smoked fish. Much smoke is wasted causing the use of fuel waste and smoking time becomes longer around 4 to 8 hours, so that in one day the partners only do one smoking process. Besides that, with the condition of smoking equipment that is open in the event of strong winds or heavy rain the partner cannot carry out the process of smoked fish. The purpose of this community service activities is to replace conventional (open) fish smoking equipment with modern cabinet / cabinet type smoking equipment to increase smoked fish production. The steps taken are the manufacture of smoking equipment, initial testing in order to maximize the use of fuel and temperature in the smoking cabinet. The next step is testing the estimated time of smoking fish and the capacity of fish in a single production. After the testing phase is completed, it is continued with the socialization stage for the manufacture and operation of the fish fume cupboard tool to partners as well as the production process assistance. The results of the service show that the amount of fuel needed is less. In addition, the time needed in one production is faster (2-3 hours) and partners can produce smoked fish every day.
Hotel Room Marketing Strategy during the January-December 2019 Period in the City of Parepare, South Sulawesi
Authors: Suardana Wayan , Ridwan Masri
Published: May 2021

Hotel room occupancy rates/sales tend to show a graphical decline in the last three years. The purpose of this study was to determine the marketing strategy for hotel rooms in Pare-pare City, South Sulawesi. This type of research is descriptive qualitative research. Data regarding marketing strategies will be obtained through direct interviews and circulating questionnaires with employees of the front office of the hotel, employees of the marketing division of the City of Parepare. The data used in this study were collected using several techniques, namely: questionnaires, interviews, observation, and documentation techniques. There are several marketing strategies carried out by hotel management who are respondents in this study, one of which is through the internet. This is believed to be a powerful tool for marketing products (hotels). Also, the strategy taken to market the rooms is through private companies, State-Owned Enterprises (BUMN), Government Agencies, and Travel Agencies in Parepare City
MICE's Human Resources Development Strategy in Increasing the Competitiveness of the Event Organizer in South Sulawesi
Authors: Kuba Dharma , Guntara Fuad
Published: May 2021

Tourism in the MICE sector is one of the fields that increases the income of the tourism sector. Business visitor/MICE expenditure in Thailand 3.5 times leisure visitor. This study aims to determine the quality and strategy of human resource development for the MICE Event Organizer in South Sulawesi. This research uses a qualitative descriptive approach. There were four informants in the study. Data collection techniques used were observation, interviews, and documentation. Data analysis techniques, namely data classified and analyzed with theories related to the object of research. The results of the research are the quality of MICE Human Resources at the Event Organizer in South Sulawesi Selatan is quite good and the MICE Event Organize HR Development Strategy in South Sulawesi, namely 3 main strategies, namely development through internships and guidance, development through education and training and career development.
Hospital Management Innovation in Public Services in Regional Public Hospitals Lanto Dg. Pasewang Jeneponto District
Authors: Lail Hijrah , Isma Aam Azatil
Published: May 2021

Services in the health sector are one of the most needed forms of service by the community. This study aims to describe the process of public service innovation carried out by the Hospital Management and to identify the factors that influence public service innovation implemented by the Jeneponto District Hospital. This research is also expected to provide input (suggestions) in the process of implementing innovation in public services to create quality services and improve the performance of the Regional General Hospital Lanto Dg. Pasewang. The research method used is descriptive qualitative. Researchers will explain the research problem in detail, namely the innovation process and the factors that influence it. Data collection was obtained through direct observation of the object of research and in-depth interviews with relevant sources, namely, Hospital Management in public services at the Lanto Dg. Pasewang Regional General Hospital led by the Hospital Director, and Heads of fields and communities involved directly feel the hospital service innovation. The results of this study indicate that Hospital Management Innovations in Public Services at the Lanto Dg. Pasewang Regional General Hospital Jeneponto Regency, have made public service innovations in improving services to the patients
SAINTIFIK BERBASIS CONTEXTUAL TEACHING AND LEARNING TERHADAP KEMAMPUAN SAINS PADA PEMBELAJARAN ANAK USIA DINI
Authors: Kesuma Igha Putri , Parwoto Parwoto
Published: May 2021

Tujuan penelitian ini untuk  mengetahui efektivitas pendekatan saitifik berbasis contextual teaching and learning terhadap kemampuan sains anak pada PAUD Al-Wildan Kec. Wonomulyo Kab. Polewali Mandar. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan penelitian kuantitatif. Jenis penelitian yang digunakan adalah  quasi-experimental design atau eksperimen semu. Teknik   pengumpulan   data   yang   digunakan  adalah observasi, tes, dan dokumentasi. Hasil perhitungan dengan menggunakan uji hipotesis-t (Separated Varian) diperoleh thitung lebih besar dibanding ttabel pada taraf signifikan dan derajat kebebasan tertentu. Sehingga dapat disimpulkan bahwa kemampuan sains kelompok anak yang mengikuti pembelajaran pendekatan saintifik berbasis CTL termasuk kategori tinggi, serta terdapat pengaruh positif penerapan pendekatan saintifik berbasis CTL terhadap kemampuan sains anak di PAUD Al-Wildan Kecamatan Wonomulyo Kabupaten Polewali Mandar.
PENGEMBANGAN KEMAMPUAN BERBICARA ANAK USIA 5-6 TAHUN (STUDI PADA RA JAMIATUL KHAER KOTA MAKASSAR)
Authors: Jafar Yuliana , Surganingsih Muqimah
Published: May 2021

Penelitian ini menelaah tentang pengembangan kemampuan berbicara anak usia 5-6 tahun di RA Jamiatul Khaer Kota Makassar. Pendekatan dan jenis pendekatan yang digunakan yaitu pendekatan kualitatif dengan jenis penelitian kualitatif deskriptif dengan Subjek penelitian  kelas B2yang jumlah anak didiknya sebanyak 14 anak terdiri dari 11 anak laki-laki dan 3 anak perempuan serta 2 orang guru kelas B. Teknik pengumpulan data melalui observasi, wawancara dan dokumentasi. Analisis data diolah dengan reduksi data, penyajian dan kesimpulan. Hasil penelitian yang telah dilakukan menunjukkan bahwa pengembangan kemampuan berbicara anak usia 5-6 tahun di RA Jamiatul Khaer Kota Makassar yang digunakan guru adalah metode bercerita, metode bercakap-cakap, dan bernyanyi sehingga dapat mengembangkan kemampuan berbicara anak.
Technology for Filling Subject Ontologies of the Scientific Knowledge Space
Authors: Каленов Николай Евгеньевич
Published: May 2021

Subject ontology in the context of this article is understood as a set of key concepts related to a certain field of science, with their semantic connections, supplemented by indexes of various classification systems describing this scientific field. Subject ontologies are a necessary component of each subspace that is part of the Unified digital space of scientific knowledge (DSSK). This article presents the results of research related to the construction of subject ontologies based on the created automated system for supporting terminological dictionaries and suggests a methodology for identifying new key terms in a particular field of science. The proposed methodology is based on the use of existing classification systems in conjunction with citation databases, such as Web of Science and Scopus for English–language publications and the Russian citation index for Russian-language publications. The methodology involves dividing the scientific field into a number of sections in accordance with the selected classification system, extracting from the CSB the core of articles related to each section, and from the articles - new author's keywords, which should constitute, in combination with the corresponding sections of classification systems, the basis of the subject ontologies of this scientific field.
Wydatki związane z pracami eksploracyjnymi – nakłady inwestycyjne czy koszty operacyjne?
Authors: PAWŁOWSKI Stanisław , KUSTRA Arkadiusz , KOZIEŁ Diana
Published: May 2021

W artykule przedstawiono sposoby ujęcia w rachunkowości wydatków związanych z pracami eksploracyjnymi. Zaprezentowanosposoby ich wyceny oraz wskazano regulacje rachunkowe oparte na MSSF 6, które dotyczą tego rodzaju wydatków. Ich ujęciefinansowe ma wpływ zarówno na zasoby jak również strumienie przychodów i kosztów przedsiębiorstw górniczych. Dla poparciaprzedstawionych tez przytoczono badania przeprowadzone na firmach eksploracyjnych w Republice Południowej Afryki, którastanowi jeden z największych rynków firm poszukiwawczych na świecie.
Phenological rhythms of decorative forms of different species of firs (Abies Mill.) collection of the Central Botanical Garden of the National Academy of Sciences of Belarus
Authors: Karaneuski R. I. , Torchyk U. I.
Published: May 2021

The article provides information on the phenological rhythms of representatives of the genus Abies Mill. and their decorative forms growing on the territory of the Central Botanical Garden. The purpose of this study was to determine the degree of adaptability of introduced species to local conditions and to establish from the possible potential use in landscaping the country. Studies have shown that in all studied species of fir, biological rhythms coincide with the climatic rhythms of Belarus, which indicates a sufficient degree of their adaptation to new conditions. At the same time, A. alba and A. nordmanniana are less winter-hardy and are damaged by spring frosts, while A. sibirica, A. concolor, A. fraseri, and A. nephrolepis are annually damaged by diseases and pests. A. holophylla, A. veitchii and A. koreana are potentially suitable for use in the country’s green building. Among the ornamental forms, A. nordmanniana ‘Lennartz’ and A. alba ‘Belopestraya’ are annually damaged by frosts. The rest of the forms of fir have successfully passed the initial test under the conditions of introduction, adapted to local conditions and are suitable for use in landscaping the territory of Belarus.
Taxonomic structure of the zoobenthos of the Lukoml GRES cooling reservoir
Authors: Lapuka I. I. , Vezhnavets V. V.
Published: May 2021

The species composition of zoobenthos in the heated and non-heated zones of the cooling lake Lukoml State District Power Station was studied. 80 taxa of bottom animals have been registered, and two new species of chironomid larvae have been identified. The bottom fauna includes a protected relict species of Pallaseopsis qudrispinosa, which is preserved in the conditions of warming.it is listed in the Red book of Belarus and the alien species – freshwater shrimp Macrobrachium nipponense. The high taxonomic diversity indicates that the Lukoml State District Power Station operation has little impact on the bottom community throughout the lake’s water area. However, species richness is reduced locally by half in the zone of influence of heated water discharge, especially in summer. Under the influence of heating, the taxonomic structure and spatial distribution at different depths change.
Study of the gene pool of the winter rye Secale cereale L. of the Republic of Belarus using microsatellite markers
Authors: Mandrusova V. S. , Gordej I. S. , Lyusikov O. M. , Shimko V. E. , Gordej I. A.
Published: May 2021

In this work, the genetic diversity of the modern gene pool of the winter rye (S. cereal L.) of the Republic of Belarus from 20 actual breeding samples was investigated using 15 microsatellite (SSR) markers to develop divergent crossing combinations in breeding for heterosis. It was shown that the formed set of SSR markers is highly effective – the informational content index (PIC) varied from 0.50 to 0.83 and averaged 0.72. The most effective microsatellite markers (SCM28, SCM43, SCM101 and SCM102) were identified and can be successfully used to study the genetic diversity of rye. It has been established that the modern gene pool of the winter rye of the Republic of Belarus is generally characterized by fairly wide genetic diversity (interpopulation variability) – all collection samples are characterized by a unique allelic composition of the studied microsatellite loci. Based on investigation results, a hierarchical clustering dendrogram was constructed, which made it possible to determine the most genetically divergent combinations of crosses. The information obtained can be used for the development of an effective scheme allowing to develop new varieties and hybrids in the practical breeding of rye for heterosis.
Genetic analysis of the human remains of the burials of the 17th–18th centuries of the Corpus Christi Church in Nesvizh (Belarus)
Authors: Shapturenko M. N. , Lugovnjov A. V. , Borovko S. R. , Pamazanau M. M. , Vakula S. I. , Kilchevsky A. V.
Published: May 2021

During archaeological excavation in the territory of the Corpus Christi Church in Nesvizh, the regular burials dated to the 17th–18th centuries were discovered. The genetic material extracted from the bones of seven unidentified individuals was analyzed using the forensic genetics approaches, including STR profiling and DNA phenotyping. The genetic examination revealed that the remains of three samples (#1, #2, #6) belonged to women, and the four others (#3, #4, #5, and #7) belonged to men. Autosomal STR-data and Y-chromosomal profiles were obtained for five samples. The kinship analysis excluded that woman #1 and men #3, #4, #5, #7 were first-degree relatives. According to the Y-STR profiles, men #3, #4, #7 referred to the haplogroup R1a, the haplotype of individual #5 corresponded to I2. The both haplogroups are widely represented in Eastern Europe, which, with a high degree of probability, suggests the Slavic origin of the individuals under investigation. To predict eye and hair color, we used the HIrisPlex DNA phenotyping system. The analysis gave the satisfactory results for woman #1 and man #7. In correspondence to the allelic variants of the 24 SNP system, woman #1 had an intermediate type of iris pigmentation and dark blond hair (p = 0.635) with dark shade (0.639), light skin tone, low tendency to sunburn, and a high probability of freckles and pigmented spots of the skin. For male #7, the HIrisPlex model predicted blue eye color with a high probability (p = 0.915), as well as blond hair color (p = 0.915) and light hair color shade (p = 0.962). Our data allow us to conclude that the unknown individuals under investigation have significant genetical and phenotypical similarity with the modern Belarusian population.
Conceptual directions of effective management of labour resources employment in agriculture
Authors: Pashkevich V. A.
Published: May 2021

Rapid information technology progress leads to increased competition both within countries and between them. This actualizes the ability of personnel to function in market conditions, as well as to master new and promising ones. All over the world, in recent years, the processes of management of labour resources employment have acquired a fundamentally new meaning in terms of achieving competitiveness of both individual organizations and countries as a whole. In this regard, economic transformations made it necessary to study new processes in the sphere of population employment, formation and regulation of the labour market, and use of labour resources in production field. The paper describes the current trends in formation of the labour potential in agriculture, results of the personnel situation analysis in the agricultural sector of Belarus. The factors determining transformation of the forms of labour organization and employment in the economy and agriculture have been systematized. The results of ranking of economic sectors by the degree of attractiveness of employment in them are presented. The toolkit for professional identification for choosing future area of employment has been systematized. Conceptual proposals for efficient management of labour resources employment in agriculture have been substantiated; the forms of implementation of management influences on the development of the industry, employment and rural areas have been clarified. The social significance of agricultural labour and the need to increase its prestige were especially emphasized. The research results can be used in development of proposals, substantiation of concepts, program and other documents in terms of problems of strengthening the labour potential of the agro-industrial complex, enhancing the labour motivation of workers in the agricultural sector, and increasing labour productivity in agricultural organizations.
Development of mounted system for controlling row crop cultivator in automatic mode
Authors: Azarenko V. V. , Komlach D. I. , Goldyban V. V. , Baranovsky I. A. , Prokopovich G. A.
Published: May 2021

Weed control automation appears to be a very promising technology based on the tremendous advances in computer processing, machine vision and robotics. Machine vision systems are based on size differences between crops and weeds and or on the regular structure of crop rows, allowing the system to recognize crop plants and control surrounding weeds. The paper provides description of the mounted system for orienting the row cultivator in rows and its displacement relative to the tractor using vision systems and automatic control. The developed technical vision system is capable of clearly identifying sugar beet leaves based on the deep learning artificial neural networks technology, and a specially developed algorithm for identifying the center of the row spacing to control the moving part of the cultivator in the required direction to level the inaccuracy of the tractor. The use of controlled mounted device with a tractor and an implement based on vision systems, the accuracy of technological operations for the row crops care, will increase the technical level of the machine and tractor unit, and reduce labor costs. Technical vision systems and automatic control of the cultivator will improve the quality of inter-row cultivation of row crops and reduce the pesticide load on the environment. The results of these studies can be used to create machines for cultivation of agricultural crops with an automated control system.
Internationalisation of Higher Education in light of national development problems
Authors: Smaliakou D. A.
Published: May 2021

The internationalisation largely determines the modern image of higher education and is considered one of the markers of the state’s national success. Slow development of internationalisation of higher education may indicate the occurrence of serious problems in national development, one way or another related to economic, political or social sustainability. In this regard, the internationalisation of higher education should be examined as an important object for socio-philosophical reflection that could shed light on the general problems of global development.
Conceptual foundations for the functioning of the consumer market
Authors: Tsiatsiorkina A. M. , Haniukou A. N.
Published: May 2021

The article is devoted to clarifying the conceptual basis for the development of the consumer market, taking into account the specifics of the current stage of social relations. The authors claim that the interconnections of participants in this market should be built on the principles of efficiency and social justice and be intended on improving the performance of the national economy. The essence of understanding these principles from the point of view of target priorities of activity of suppliers of consumer goods, subjects of trade, the enterprises of real sector of economy which are not directly involved in manufacture of consumer goods, and also activity of financial and credit institutions, the state and interests of the end buyer is opened. The purpose and objectives of the consumer market and the tools for their implementation are outlined. Special emphasis is placed on the importance of price regulation measures and the need for them to comply with the principles of efficiency and social justice. The most important factors of personal consumption goods pricing are considered: supply and demand balance, production and sales costs, consumer value, availability of warehouse stocks, state of the monetary sphere, growth of the global economic integration, application of economic sanctions and competition level. The conclusion was drawn that it is advisable to take a comprehensive approach to studying the stated topics.
STARTUP MARKETING STRATEGY TO ATTRACT VENTURE CAPITAL AT THE AGE OF DIGITALIZATION
Authors: Kanishchenko Olena , Kuznetsova Yuliia
Published: May 2021

The article deals with the current state of startup ecosystem, its constraints and incentives, comparisons with traditional business models. The authors pay attention to an issue of attracting venture capital to finance newborn projects in the modern world. The key problems of the startups are outlined in the paper, an important fact that the ecosystem is getting more competitive and the investors are getting more cautious. The paper summarizes the traditional marketing tools for strategy development and justifies the possibility of their use in building up a startup business model. The features of attracting venture investments are identified and the specifics of the venture investor-consumer are determined. The authors' approach to the creation of a venture capital investment strategy is proposed, and each stage is considered with appropriate management concepts and models. The choice of the most effective instrument for analyzing the macromarketing, micromarketing environment and internal environment of startup obviously depends on market location and type, industry, size of the company, resources, market type, life cycle of the market / product, etc. Many tools for marketing analysis in the modern theory and practice of marketing have been named with the aim to popularize. The paper also considers the influence of coronavirus epidemy of to attract money and figures out some basic information how to prevent such a situation. The key future threats of the market are named. The importance of marketing research in the age of digitization has been explained and proven.
A STRATEGY DEVELOPMENT FOR A SMOOTH TRANSITION INTO THE REMOTE STUDIES IN LATVIAN EDUCATION INSTITUTIONS IN A PANDEMIC
Authors: Dehtjare Jevgenija , Babics Igors , Verdenhofa Olga , Riashchenko Viktoriia
Published: May 2021

The aim of the abstract is to investigate challenges the secondary and higher education institutions face during the pandemic times in Latvia and to discuss strategy to be developed in an order to ensure smooth transition into the remote study process with the help of a technological inventory appropriate to be used for remote study process. Challenges both secondary and higher education institutions and their staff experience have to be analysed as well, altogether with the outcomes. A combination of the remote and in-class education, issues and benefits are overviewed in the paper as well. ISMA, the University of Applied Sciences and its transition approach were examined thus establishing strong practical benefit of the research. The research problem is to analyse existing challenges education establishments in Latvia used to face with during the period of pandemic and to examine solution strategy and tools to be applied in an order to establish smooth transition from in-class to a remote study process. The conclusion of the research: no doubts the establishment of the transition process from in present studies into the remote mode was challenging and complicated, however it was realised in a consonance of the frameworks and recommendations designed both by the European and Latvian public bodies. The process of remote studies is challenging, still many advantages were discovered and this let to conclude the approach of combined education has a right to be applied even after the pandemic is over. The outcomes of the research are also beneficial for other educational establishments of Latvia and abroad, thus ensuring known approach when rapid and clear transition strategies must be taken. The developed strategy might be applied in case if there is a necessity to ensure establishment of remote studies within short period of time.
TRUST ASSET MANAGEMENT: ESSENCE AND FEATURES
Authors: Perminov Stanislav , Djakona Valentina
Published: May 2021

The article examines the essence of the concept of "trust asset management" in the banking system. The article examines the essence of the concept of "trust management" in the banking system. Various approaches to defining the essence of trust management in scientific and business literature are systematized, various nuances of its legal and economic interpretation are presented. The subjects and objects of trust management, the system of relationships between the main subjects are named and disclosed. The regulatory framework for the practice of trust management has its own characteristics at the national and international levels. The common couples and differences of different models of organization of trust activity are highlighted. The main approaches to the classification of trusts, the main types of trusts are revealed and their features are determined. The forms of trust management are very diverse and can differ in the purposes of creating trusts, methods of creation, depending on the role of the owner and trustee, depending on the financial instruments used. The purposes of the use of trust management, as well as certain risks of using the control system (legal uncertainty, presence of risk, imperfection of state regulation, etc.) are characterized. In world practice, this service is constantly developing and is increasingly becoming an important integral part of banking in different countries and regions.
Isolation of four types of bacteria that cause kidney damage in broiler chickens
Authors: Al-Hiyali Harith M.
Published: May 2021

This study was conducted on 80 cases of damaged kidneys received bypoultry disease diagnostic centers in Baghdad. Four microorganisms were isolatedE.coli , Proteus milabilis , Pseudomonas aregenosa and Klebsiella pneumoniaand formed 55, 22.5 , 17.5 ,and 5% of the infection respectively . While no anykind of bacteria were isolated from kidneys of healthy chicks. To be sure the E.coli could be a cause of kidney damage. An experimental infection with E.coliwas carried out on 40 chicks, three weeks old, and randomly divided into twogroups. Chicks of the first group was inoculated intravenously with 0.5 ml of fieldisolated E. coli suspension containing 2x107 colony forming unit (CFU), while thesecond group was inoculated with 0.5 ml distilled water and considered as controlgroup. The results revealed that chicks inoculated with E.coli showed 70%mortality rate with severely congested swollen kidneys with acute interstitialnephritis. However, this study gave information on kidney damage widely spreadat this time; therefore, it could be recommended for other studies to be hold in thefuture on the other causative agents of each case.
Histological study of the quail spleen (Coturnix coturnix coturnix )
Authors: Hamza Luay O.
Published: May 2021

The present study revealed that the spleen of the quail is coated byafibrous capsule have two distinct layers , an outer and inner , the capsule beingcovered by athin layer of peritoneal membrane . The spleen comprises twodistinct regions , the white pulp and red pulp in addition spares or trabecule .The white pulp represernt the major part of the organ , it is alymphatic tissuethat could be differentiate into two forms : diffuse and nodular lymphatic tissuewith medium and small size arteries represent the branches extend from thelarge trabecular arteries . Then these arteries branch into arterioles surroundedby sheath of reticular and lymphatic cells called Schweigger Sediel sheath .The red pulp has randomly distributed between the white pulp regions , itconsist of cellular cord that surround the venous sinuses which had irregularshape lined endothelial cells separated by small gaps freely .The capsule consist of two layer , an outer layer that represent largecollagen fiber while the inner layer represent large muscular fiber , thus themarginal zone between the white and red pulp is absent . the ellipsoid body waspresent in the white pulp more than the red pulp . In this study there are two typeof nodules , type T nodule and type B were present . The percentage of the firstnodular type is more than the second , which is the important character of thespleen of quail differ from other fowl
Effect of time of using feed blocks as supplementary feed on the weightchanges and reproductive performance of Awassi yearling ewes depend on crop residues as basal diet
Authors: Ibrahim Hadeel K.
Published: May 2021

This study was conducted to evaluate the Effect of time of using feedblocks (FB) as supplementary feed on the weight changes and reproductiveperformance of Awassi yearling ewes depend on crop residues as basal diet. .Sixty Awassi yearling ewes (mean live weight 39.51 kg) aged 12-13 monthswere allocated into four groups according to their live weight. First group (T1)fed conventional diet (barley grains + straw). The second group (T2) fedconventional diet plus FB during pre and post mating. The third group (T3) fedconventional diet plus FB during pre and mating. The fourth group (T4) fedconventional diet plus FB during post mating. The results of this experimentshowed that using FB as supplementary feed reduced the weight losses ofAwassi yearling ewes. FB supplementation improved conception rate of Awassiyearling ewes as compared with control group (T1). The T2 group had thehighest conception rate (86.66%) followed by T3 and T4 (73.33%) and thelowest group T1 (66.66%). Using FB during pre mating (T2, T3) reducedmating season of Awassi yearling ewes were 70-82% of these lambed from 1stcycle. Lambing percentage increased considerably due to FB supplementation.The lambing percentages were 100, 87, 80 and 73% for groups T2, T3, T4 andT1 respectively.
Post Partum Pyometra In Iraqi Buffaloes : Clinical and Therapeutical Study
Authors: Sultan A. Sh.
Published: May 2021

The study was conducted on 118 buffaloes suffering from openedpyometra 20-30 days post partum in AL-thahab AL-abiadh village west ofBaghdad Province, their ages ranged from 3-6 years.They were divided randomly in to 4 groups . Group one included (27 buffalo)treated with 15 mg of PGF2α ( Prosolven )R IM, The 2nd group (32 buffalo)treated with 15 mg of PGF2α and 15 mg estradiol benzoate IM . The 3rd group(29 buffalo) treated with 15 mg of PGF2α and 50 . 100 ml of lugol’s iodine 0.5% intra-uterine.The 4th group (30 buffalo) treated with 15 mg of PGF2α and 4 gm ofOxyteracycline 20% (20 ml of Oxy. plus 50-100 ml disilled water) intra-uterine.Results showed that the 1st and 2nd response in 4 treated groups were66.2%, 84.3%, 79.3% and 86.6% respectively .The response was high in the 2ndand 4th group (P < 0.01). These responses represent also the conception rate forthese 4 treated groups. The means ± SE of days open for above groups were98.4± 6.4 ,84.2 ± 4.4 ,97.3 ± 3.8 and 82.7 ± 4.6 respectively ,the second andfourth group were significant (P < 0.01).The number of newly born calves was 94 calves (46 male,48 female) Thealive were 87(92.6%) and dead 7 (7.4%), so we conclude that the PGF2α has aneffective role in the treatment of pyometra in buffalo and it’s effect increasingwhen it combined with oxytetracycline 20% and estradiol benzoate together .
Quantitation of Leydig Cell in Testicular Biopsies of Gossypol Treated rats
Authors: Al Bayaty Muhannad A. A.
Published: May 2021

Leydig cell density was evaluated quantitatively in bilateral testicularbiopsies from twenty male rats of two equal groups Gossypol treated andcontrol. The method utilized for this quantitation is based on the determinationof total number of Leydig cells, Leydig cell clusters and seminiferous tubules inthe entire histological section of each biopsy and the calculation of the followingindices: mean Leydig cells per seminiferous tubule, mean Leydig cell clustersper seminiferous tubule and mean Leydig cells per cluster. A significant positivecorrelation between Leydig cells per tubule and Leydig cell clusters per tubulewas demonstrated. The results of indices curve showed shifted all the curves tothe right in Gossypol treated group, a significant reduction in plasmatestosterone levels of Gossypol treatment group as compared to control groupwhich is due to decrease in Leydig cells number, suggesting that determinationof Leydig cell clusters per seminiferous tubule in testicular biopsies is anobjective and clinically applicable method for quantitative evaluation of Leydigcell density and indirectly evaluated the secretary activity of the testicularLeydig cells. The results are attributed to the direct effect of Gossypol onsecretary site of testosterone in Leydig cells or presumably indirect disturbanceof hypothalamic – pituitary gland – Leydig cells axis. An Association ofGossypol treatment with Leydig cell hypo-function and decrease number of cellswas noticed for the male rat testosterone level. To our knowledge this is the firstreport of quantitative analysis of Leydig cell density in rat with Gossypoltreatment and it is suitable for clinical evaluation of testicular dysfunction.التأثر
Changes of general & physical characters of sheep wool in Induce copper deficiency in Awassi sheep
Authors: Khalidi Jinan Ali
Published: May 2021

To induce copper deficiency in sheep 15 Awassi ewes were choosen from theveterenary medicine collage and randomly divided into three equal groups for theexperimental period (18 weeks).the 1st group were fed on balanced concentrated diet with low level of copper(2.6) mg/day was used to feed the primary deficiency group while the 2nd groupwere fed on a balanced concentrated diet contained 5.2 mg/day copper in additionof the green food and the protein ratio and energy level were considered. Thesecondary deficiency group received an oral mixture of ammonium molybdate100 mg with 1 g of sodium sulphate in 100 ml of water daily.Wool samples from the ewes and their lambs were collected to study thehanges in wool physical traitsThe experimental ewes were treated in two different ways. The primarydeficiency group fed on balanced concentrated diet contained high level ofcopper (7.4) mg/day, while the secondary deficiency group treated orally withcopper sulphate (1.5) g/ewe/day dissolved in water for (6 weeks). After twoweeks of treatment the parameters raised and the ewes in the two groups lookedmore healthy, the wool start to grow and by the end of that period all symptomsand changes return to normal in comparison with the control group
Ruminal acidosis in local bucks fed on al-zahdydates
Authors: K. Laiby A.
Published: May 2021

Ruminal acidosis was induced experimentally in local bucks fed onAL-zahdy dates at 20 and 40 g/kg B.W. daily. Two groups of five animalseach beside another group of five animals as a control reseved 20g/kg B.W.of concentrates beside green roughage. One animal from each group wassurgically provided with ruminal fistula. The experiments lasted for fourweeks during which the animals examined clinically daily, and ruminal fluidand blood samples were collected weekly.The results showed that theanimals in the two experimental groups show significant rise in the means ofrespiratory and pulse rates,but not in body temperature.The ruminalcontractions ranged between weak and reduced in the 1st experiment totemporary loss of contractions in the 2nd experiment. All experimental goatsmanifested weakness, depression, loss of appetite, however, temporaryrecumbency was noticed in the goats of the 2nd experiment. The color of theruminal fluid was light to dark green in the control group while theexperimental groups showed light to dark brown color .The pH reached it'slowest levels, and the number and activity of the microflor altered afteramount of feeding on dates in the experimental groups to become reduced ordead after six and five hours respectively. The positive to negative bacterialratio changed in the experimental groups. The level of volatile fatty acids,lactic acid concentrations and ammonia nitrogen in the rumen increased.Also the experimental animals showed biochemical changes in all bloodparameters. Feeding of bucks on 20 g/kg B.W.of Al-Zahdy dates dailycaused a simple form of ruminal acidosis, while 40 g/kg B.W.of dates dailycaused the subacute form of acidosis.
Effect of Adding Poultrygrow 250 and Cr-Yeast in the Productive Performance and Some Health Aspects of Broiler Chicks
Authors: AL-Kassi Galib. A.
Published: May 2021

A total of 300 one day old unsexed broiler chicks were divided into threedietary groups which were: -T1: Un-treated control.T2: Poultrygrow 250 treated group.T3: Cr-Yeast treated group.Results have shown that the addition of Poultrygrow 250 and Cr-Yeasthave significantly (p < 0.05) improved the performance of broilers express inweight gain and feed conversion ratio compared with control group. The studyshowed an increase in red blood cell and hemoglobin and reduce in hetrophil /Lymphocyte ratio.It was concluded that the supplementation of poultrygrow 250and Cr-Yeast in the diet of broiler chickens could improve the performance ofthe birds.
The Effect of Licorice roots powder on experimental Infection of infectious bursal disease in broiler chickens
Authors: Kassab A. K.
Published: May 2021

This study was conducted to investigate the effect of Licorice roots powder for 35 days in reducing the severity of infection with infectious bursal disease (IBD)and the immune response and performance of broiler chicks .A Total of 150 day old broiler chickens were divided into 5 groups and treated as follows :

Group 1: infected with IBD virus at 21 days of age. Group 2: infected with IBD virus at 21 days of age and given 1 gm of Licorice

roots powder /1 L of drinking water one day after infection . Group 3 : given 1 gm Licorice roots powder / 1L of drinking water at day one

of age and infected with IBD virus at day 21 of age . Group 4:given 1 gm Licorice roots / 1 L of drinking water at 22 days of age

.Group 5: untreated control. Antibody (Ab) of IBD titer was measured by ELIZA , the serum total protein (STP) the serum Globulin(SG)and the blood picture were determined , the water content of the droppings was measured , the body weight , food intake was recorded, there was increase (P<0.01) in the (Ab)titer of IBD virus in the group3 comparing with the other groups , the bursa / body weight index (B:BW)three days after infection was increased (P<0.01) in group1 , the STP , the SG , the PCV and RBCs was increased (P<0.01) in group 3 at age 27 days the food intake (FI) Food conversion ratio (FCR) and body weight (BW) in Group 3 were

significantly increased , the dropping water content was significantly (P<0 .01)increased in group 3 in comparison with other groups at the period from 23-27 days of age, the morbidity and Mortality rate were significantly lower in group 3 and then 2 in comparison with group 1 (50 % , 63.3 %, 90 % ) and (6.6

% , 16.6 % ,30%) respectively
Genetics aspects of reproductive performance for Holstein
Authors: Al-Samarai F. R.
Published: May 2021

A total of 16678 records of age at first calving and ages at next calving ,in addition to 14058 records of calving interval belonged to Holstein cows wereanalysed over period from 1992 to 2003 , at the Nasr Dairy Cattle Station,United Company for Animal Resources Ltd., Al-Soueira ( 50 Km South ofBaghdad ). Data was analaysed using General Linear Model within the SASprogram to study the effects of some fixed factors on the studied traits .Components of variance for the random effects was estimated by theMinimum Variance Quadratic Unbised Estimation Procedure ( MIVQUE ) , alsophenotypic trend was estimated for all traits .The overall means for age at first calving till the age at sixth calving were48.17 , 62.77 , 77.41 , 91.35 , 105.53 months respectively , and the heritabilityfor the same traits was 0.10 , 0.01 , 0.03 , 0.04 , 0.02 , 0.11 respectively .whereas the overall mean of calving interval and heritability was 458.59 daysand 0.07 .The results obtained that there was a significant effect of year of birth onage at first calving , whereas the season of birth was not .All the estimates of heritability were low so it’s reflect the role ofenvironment factors in the traits variation.Phenotypic trend was negative andsignificant ( p <0.01 ) for age at first calving ( - 1.05 month / year ) and calvinginterval (- 2.03 day / year ) .