bluuebunny/crossref_metadata_2025 huggingface dataset:
PINHEIRO, Marcus R.; MACHADO, Cristina A. (trads. & eds.). O Tetrabiblos de Ptolomeu: tradução comentada dos capítulos filosóficos e estudo sobre o texto e seu conteúdo cosmológico. Maringá: Eduem, 2018. 202 pp. ISBN 978-85-7628-739-1.
Authors: Pinto de Brito Rodrigo
Published: February 2023

Resenha de "PINHEIRO, Marcus Reis; MACHADO, Cristina de Amorim (trads. eds.). O Tetrabiblos de Ptolomeu: tradução comentada dos capítulos filosóficos e estudo sobre o texto e seu conteúdo cosmológico. Maringá: Eduem, 2018. 202 pp. ISBN 978-85-7628-739-1".
Monovision in a case of bilateral high hyperopia by refractive lens exchange with customised foldable IOL
Authors: Pereira Savio , Nikhil R P , Sute Smith Snehal , Ganesh Sri
Published: February 2023

This case report describes about the feasibility of monovision in a case of bilateral high hyperopia for achieving spectacle independence following refractive lens exchange (RLE) A 19-year male presented with diminution of vision (DOV) since 15 years oculus uterque (OU). On examination, unaided distance visual acuity (UDVA) was 20/1000 in OU and corrected distance visual acuity (CDVA) was 20/125, N18 with a refraction of +12.25DS/+1.25DC (DS: Dioptre sphere, DC: Dioptre cylinder) @140 degrees in oculus dexter (OD) and +12.75DS/+1.50DC @25 degrees in oculus sinister (OS). Primary diagnosis was high hyperopia. Refractive lens exchange with a monofocal intraocular lens (IOL) and monovision by targeting dominant OS to emmetropia and non-dominant OD to myopia of -2.00D was planned for the patient. The IOL power was calculated by multiple formulae and we decided to implant +46.0D in OD and +47.0D in OS calculated using personalized A-constant. At post-op day 15, no complications were noted, UDVA in OD was 20/250 and in OS was 20/200 and CDVA was 20/125 OU, uncorrected near visual acuity (UNVA) was N18 OU with a refraction of -2.00DS/-2.50DC @95 degrees in OD and +0.25DS/ -1.75DC @125 degrees in OS (Monovision) which was stable even at 6 months follow up RLE in high hyperopia requires meticulous planning and biometry to give good results. Monovision can be planned in such a case to deliver spectacle independence. It can thus be a valuable tool in the armament of refractive surgeon.
Continuous versus intermittent mask use by nurses in COVID times (CIMNIC) – A CUSUM study
Authors: Gupta Neeraj , Agarwal Poojan , Sachdev Anil , Gupta Suresh , Gupta Dhiren , Rajan Sudha , Mathew Sijimol , Anumol T. P. , Chugh Parul
Published: February 2023

Objectives:

The coronavirus disease 2019 pandemic has reinforced the use of personal protective equipments in healthcare settings. Although filtering face piece 2 respirators provide adequate protection from the aerosolised viral spread, their prolonged use is often associated with subjective discomfort. The study aimed to identify whether an intervening mask-free period is less harmful in terms of discomfort and desaturation when compared against continuous use for 6-h.

Material and Methods:

This was a prospective and interventional study. A cohort of 87 previously healthy nurses from a multidisciplinary tertiary care hospital were recruited. Study participants were subjected to continuous and intermittent (with 15 min break) mask use, each for a 2-month duration, during their 6-h clinical shifts. Baseline and post-shift oxygen saturation (SpO2) were compared in real time using cumulative sum (CUSUM) statistics. Comfort level was also assessed on a scale of 0–10 in the two groups with 10 subjective parameters.

Results:

Nurses have experienced a significant drop in SpO2 in both phases with 525 and 984 recordings in continuous and intermittent mask group, respectively. The mean % (2SD) saturation drop in the two groups was 4.688 (39.35) and 1.169 (2.62). The overall discomfort level was more in the continuous phase (8.89 ± 1.610) than in intermittent (7.28 ± 3.216) mask use. CUSUM statistics helped in the real-time monitoring of subjects in the intermittent mask group.

Conclusions:

Significant adverse health effects in healthcare workers are highlighted using objective and subjective parameters such as desaturation and discomfort levels while using protective face masks. A mask-free period of 15 min, in between their duty shifts, might help reduce the unfavourable effects without compromising efficacy.
Comparison of the accuracy of intraoperative lateral fluoroscopy versus postoperative computed tomography in spinal fusions
Authors: Altaf Sehrish , Rehman Lal , Javeed Farrukh , Ahmed Anas , Hatif Yousra
Published: February 2023

Background:

This study compared the accuracy of intraoperative lateral fluoroscopic images versus postoperative computed tomography (CT) 3D studies in the treatment of thoracolumbar spinal fusions.

Methods:

In a tertiary care hospital (study duration 6 months), we compared the use of lateral fluoroscopic images with the postoperative CT scans in 64 patients with thoracic or lumbar fractures undergoing spinal fusions.

Results:

Out of the 64 patients, 61% were lumbar followed by 39% thoracic fractures. In the lumbar spine, the accuracy of screw placement utilizing lateral fluoroscopy versus postoperative CT 3D was 97.4%, while in thoracic spine, accuracy was reduced to 84.4%. Of the 64 patients, just 4 (6.2%) patients demonstrated lateral pedicle cortex penetration, 1 (1.5%) patient had a medial pedicle cortex breach, while none exhibited anterior vertebral body cortex penetration.

Conclusion:

This study documented the efficacy of lateral fluoroscopy in intraoperative thoracic and lumbar spinal fixation as confirmed by postoperative CT 3D studies. These findings support the continued use of fluoroscopy rather than CT intraoperatively to lower the risk of radiation exposure to both patients and surgeons.
Role of a medical student neuro-society organized neurosurgical conference: The Glasgow neuro experience
Authors: Ashraf Mohammad , Ismahel Hassan , Lub Sytske , Gardee Ameerah , Evans Vivienne Eloise , Middleton Eilidh Elizabeth Stewart , Chaudhary Attika , Cheema Huzaifa Ahmad , Shahid Abia , Salloum Laulwa Al , Szilagyi-Nagy Eva , Omar Samia , Mathieson Calan , Baird Tracey Anne , O’Kane Roddy , Ashraf Naveed
Published: February 2023

Background:

Entering neurosurgical training in the United Kingdom demands extensive prior commitment and achievement, despite little to no exposure to the specialty in medical school. Conferences run by student “neuro-societies” offer a means to bridge this gap. This paper describes one student-led neuro-society’s experience of curating a 1-day national neurosurgical conference supported by our neurosurgical department.

Methods:

A pre-and post-conference survey was distributed to attendees to ascertain baseline opinions and conference impact using a five-point Likert Scale, and free text questions explored medical students’ opinions of neurosurgery and neurosurgical training. The conference offered four lectures and three workshops; the latter provided practical skills and networking opportunities. There were also 11 posters displayed throughout the day.

Results:

47 medical students participated in our study. Post-conference, participants were more likely to understand what a neurosurgical career involves and how to secure training. They also reported increased knowledge about neurosurgery research, electives, audits, and project opportunities. Respondents enjoyed the workshops provided and suggested the inclusion of more female speakers in future.

Conclusion:

Neurosurgical conferences organized by student neuro-societies successfully address the gap between a lack of neurosurgery exposure and a competitive training selection. These events give medical students an initial understanding of a neurosurgical career through lectures and practical workshops; attendees also gain insight into attaining relevant achievements and have an opportunity to present research. Student neuro-society-organized conferences have the potential to be adopted internationally and used as a tool to educate on a global level and greatly aid medical students who are aspiring neurosurgeons.
Emocje/uczucia nauczycieli podczas przeprowadzania rozmów z rodzicami/ opiekunami podopiecznych
Authors: Figurska Emilia
Published: February 2023

Polska szkoła przechodzi ciągle przez szereg reform, podczas których nikt nie zastanawia się nad stanem psychicznym nauczycieli oraz nad tym, jak ich wspomóc w radzeniu sobie z problemami, jakie spotykają w pracy. Celem artykułu jest zwrócenie uwagi na emocje/uczucia nauczycieli podczas przeprowadzania rozmów z rodzicami/ opiekunami swoich podopiecznych. Nauczyciele odczuwają na swych barkach ciężar edukacji młodego pokolenia, radzenia sobie z przeróżnymi zachowaniami uczniów i ich problemami oraz informowania rodziców o wszystkich postępowaniach ich podopiecznych (i dobrych, i złych). Mało kto zwraca uwagę na nauczyciela, na emocje/uczucia, które mu w pracy towarzyszą.
Synthesis and Photothermal Properties of UV-Plasmonic Group IV Transition Metal Carbide Nanoparticles
Authors: Margeson Matthew , Esfahani Monfared Yashar , Dasog Mita
Published: February 2023

Refractory nanostructures are low-cost and chemically and thermally robust alternatives to noble metal based plasmonic materials. Transition metal nitrides have received much of the attention lately, but there has been less emphasis on closely related non-layered carbide counterparts. In this work, plasmonic group IV transition metal carbide (TiC, ZrC, and HfC) nanostructures were prepared using a facile magnesiothermic reduction method which yielded phase pure product. TiC, ZrC and HfC with rock salt crystal structure and an average particle size of 24, 31, and 42 nm, respectively were obtained by reacting corresponding metal oxide, magnesium, and biochar in solid-state. Calculations performed using finite element method predicted these group IV carbide nanostructures to have localized surface plasmon resonance in the UV region between 150 175 nm. The photothermal transduction efficiency of each carbide was explored to further verify the plasmonic behavior. HfC was found to have the highest photothermal transduction efficiency (73%), followed by ZrC (69%), and then TiC (60%) at 365 nm.
Antibiotic resistance – what can be done? A review
Authors: Kisil Olga  V. , Gabrielyan Nina I. , Maleev Viktor V.
Published: February 2023

Serious work is being carried out in the world in the field of combating antibiotic resistance: reducing the prescribing of antibiotics, banning the use of antibiotics as stimulators of animal growth, improving infection control. Antimicrobial resistance is systematically monitored not only in every medical center, but also at the national level. The collected data is successfully used to implement local and national recommendations on the optimal use of antibiotics.
New opportunities for complex treatment of oropharyngeal candidiasis in HIV-infected patients in the later stages of the disease
Authors: Charushin Artem O. , Elovikov Aleksey M. , Charushina Irina P.
Published: February 2023

Treatment of recurrent oropharyngeal candidiasis (OPC) in HIV-infected patients is a serious clinical problem due to the emergence of resistant Candida strains, the risk of invasive disease, and high economic costs, which warrants the need for new treatment regimens.
Aim. To improve the treatment regimen of OPC in the later stages of HIV infection by combining the complex herbal medicinal product Tonsilgon N with fluconazole and evaluate the effectiveness of this combination.
Materials and methods. A comparative randomized clinical study included 65 patients divided into observation and comparison groups, receiving fluconazole plus Tonsilgon H and fluconazole monotherapy, respectively, for 7 days. On days 1 and 8, the severity of OPC clinical signs was assessed using a visual analog scale. The secretory immunoglobulin A in saliva was measured as a criterion for changing the level of local mucosal protection of the oral cavity and pharynx.
Conclusion. This treatment regimen for oropharyngeal candidiasis in patients with HIV infection in the later stages of the disease (IVBIVC) with fluconazole and Tonsilgon N is effective, which is confirmed by a significantly more pronounced regression of clinical signs (pMU0.01), as well as an increase in the level of secretory immunoglobulin A in the oral fluid (from 0.620.33 g/L to 0.810.18 g/L; p0.05).
TỔNG HỢP VÀ ĐẶC TRƯNG VẬT LIỆU NANO ZnFe2O4
Authors: Nguyễn Lê Mỹ Linh , Đỗ Mai Nguyên , Đỗ Thị Ngọc Cẩm , Trần Thị Minh Hà
Published: February 2023

Trong nghiên cứu này, vật liệu nano ZnFe2O4 được tổng hợp thành công bằng phương pháp thủy nhiệt kết hợp với nung. Các yếu tố ảnh hưởng đến quá trình tổng hợp vật liệu như thời gian thủy nhiệt, nhiệt độ thủy nhiệt và nhiệt độ nung đã được khảo sát. Vật liệu tổng hợp được đặc trưng bằng phương pháp nhiễu xạ tia X (XRD), hiển vi điện tử quét (SEM), phổ hồng ngoại (FT-IR) và hấp phụ/khử hấp phụ ni tơ (BET). Kết quả cho thấy tinh thể spinel ZnFe2O4 có trật tự cao được tổng hợp ở nhiệt độ thủy nhiệt 120 °C, thời gian thủy nhiệt 24 h và nhiệt độ nung 500 °C.
ĐỊNH LÝ CƠ BẢN CHO CÁC ĐỐI ĐẠI SỐ TRÊN VÀNH DEDEKIND VÀ ÁP DỤNG
Authors: Nguyễn Đại Dương
Published: February 2023

Bài báo này nghiên cứu tính hữu hạn địa phương của các đối đại số được biết đến như là định lý cơ bản cho các đối đại số trên vành Dedekind. Trước tiên, chúng tôi đưa ra một chứng minh của tính chất này cho các đối đại số xạ ảnh như các môđun trên một miền iđêan chính mà không sử dụng định lý cơ bản cho các đối đại số trên một trường. Tiếp theo, chúng tôi đưa ra một phiên bản của định lý cho các đối đại số phẳng trên vành Dedekind, dĩ nhiên là mở rộng của định lý trên một trường. Cuối cùng, chúng tôi áp dụng các kết quả này cho vành tọa độ của các lược đồ nhóm affine phẳng.
Some new oscillation criteria for certain class of fractional partial differential equations with damping
Authors: S Priyadharshini , V Sadhasivam
Published: February 2023

In this paper, we obtain some new oscillation criteria for certain class of fractional partial differential equations with damping. Using the generalized Riccati technique and integral averaging method, new oscillation criteria are established.
Irredundant complete cototal dominating set
Authors: W Anjaline , A Stanis Arul Mary
Published: February 2023

The complete cototal domination set is said to be irredundant complete cototal dominating set if for each u ∈ S, NG [S − {u}] ≠ [S]. The minimum cardinality taken over all an irredundant complete dominating set is called an irredundant complete cototal domination number and is denoted by γircc(G). Here a new domination parameter called an irredundant complete cototal dominating set was introduced and the study of bounds of γircc(G) was initiated.
The India-Myanmar Kaladan Project: Vision and Reality
Authors: Subir Bhaumik
Published: February 2023

India’s recent connectivity projects in the East, like the USD 484 million Kaladan Multi-Modal Transport Project, stem from a compulsion imposed by the sub-continent’s post-Partition geography. Pakistan lost its eastern wing in a bloody civil war in 1971 because it was logistically impossible for its army to hold on to an alienated province with millions of Bengalis up in arms and their insurrection fully backed by India. India did not lose its restive ‘Seven Sisters’ in the Northeast, but a spate of violent insurgencies by battling ethnicities (Naga, Mizo, Manipuri, Assamese, Bodos and other tribes) challenged Delhi’s control over the remote region. That has compelled post-colonial India to seek alternate trans-national connectivity to the region to get round the limitations imposed by the 21 km wide ‘Siliguri Corridor’, the only land link connecting the Indian mainland to the Northeast. A combined armoured-infantry-airborne thrust by China through the Zompheri Ridge down the Chumbi Valley and Jaldhaka, cutting off this Siliguri Corridor – this is the worst nightmare scenario for India’s military planners.
Russia-Ukraine War: Impact on Russian Civil Society
Authors: Sona Singh
Published: February 2023

On February 24 this year, Russia launched its “special military operations” against Ukraine and that set-in motion a chain of events which have had immense repercussions on all forms of Russian life. According to President Putin, this operation on Ukraine was necessary in order to “denazify” and “demilitarise” Ukraine. Many Russian experts believed that the operation was long overdue and the Russian side had been preparing for it, especially in the wake of the large Russian military presence on its border areas with Ukraine from 2021 onwards. In this article, I have argued how the Russian civil society, a fragile space struggling to reclaim its place in the country in the aftermath of the Foreign Agents Law in 2012, is impacted by the Russia- Ukraine war and how it conducts itself now will decide the future of civil society space in Russia.
Social networking sites usage and psychological wellbeing: A survey among Telangana youth
Authors: Santhosh Kumar Putta  , Stevenson Kohir  , Rana Ashish Chavan
Published: February 2023

"Societies have always been shaped more by the nature of the media by which men communicate than by the content of the communication," said Marshall McLuhan in the 1960s, commenting on the influence of broadcasting medium; further, he adds that Innumerable confusions and a profound feeling of despair invariably emerge in periods of great technological and cultural transitions (McLuhan, 1967). India is going through such a transition in this Information age, especially after the jio effect (Ghosh, 2019), which has bought millions of online by providing free High speed 4G data for more than six months as an introductory offer to increase its subscribers, both urban and rural Indian youth were quick to take advantage of the offer as youth instinctively understood the present environment (McLuhan, 1967). As of August 2021, India is the second-largest online market in the world with over 749 million internet users, internet access and use largely vary in the country due to the socio-economic divide and the number of users varied greatly among the urban and rural population (keelery, 2021). 90% of the internet users in India are on social networking sites; most of them are between 18 to 24 years of age (Keelery, Number of social network users India 2015-2040, 2021).Passive browsing social networking sites (SNSs) correlates with poorer wellbeing (Verduyn, et al., 2015). However, less research is conducted that examined the impact of social networking usage on the psychological wellbeing of Indian youth and compared rural and urban social networking usage. For a diverse sample of college students (N = 629, Mage = 21, SDage = 46.2% female), for this study social networking usage is considered as the amount of time spent on SNSs in a day and how long they have been using SNSs (in years).while the amount of time sent on SNSs  has an impact on rural Indian youth, how long they have been on SNSs has an impact on psychological wellbeing of the urban Indian youth and neither the amount of time or how long they are using SNSs has impacted the semi-urban Indian youth.
Digital Dispossession and Gendered Discrimination in Use of Smartphone by Women in Marginal Settings in India
Authors: Namita Nagpal  , Gita Bamezai
Published: February 2023

Women are becoming avid user of mobile phones and are increasingly turning to technology to up-skill themselves which offers scope to reduce gender inequalities even in marginal settings. Technology has ushered in a development offering which holds tangible promise to reduce social barriers by providing training that boosts proficiency. Digital media offers scope and opportunities of reshaping systemic gendered imbalances of social structure. Women, in marginalized settings, hemmed in by deeply rooted patriarchal structures may find emancipation by use of the digital technologies in their everyday routine which may accelerate restructuring of their social and cultural realities. The role of digital media in struggle for women’s inclusion in the civil society and gender equality has been considered as emancipatory. This is particularly so because technology provides an avenue for women’s engagement where their physical mobility is restricted and voices deliberately muted. However, patterns of social attitudes may underpin internet cultures if viewed through a gendered prism. There is a persistent gender gap in mobile phone ownership and usage in the low income setting areas and women tend to experience certain barriers more acutely than men. This deprivation in terms of being unconnected widens the gap of marginalization. The present study is an attempt to explore entry of digital technologies in a given culture of slum area in urban settings and subsequent negotiations for the concomitant changes in the discriminatory roles and responses. Two research objectives that have been explored are- factors that engender marginalisation of women and their gendered aspects constraining their digital literacy and competency; the second objective is to describe disruptive impact of digital devices on traditional gender roles and responsibilities that determine the relationships and status in the family. A sizeable percentage of the slum dwellings have electricity, television and smartphones even though lacking toilets. The paper uses qualitative method and tools of observation, focus group discussions and interviews to study mobile and smartphone usage of women living in slums to capture their everyday mobile experience and internet adoption in the context of existing gender inequalities. The study finds that power dynamics within the household play roles that mark digital in/exclusion and (dis) empowerment. It is obvious that digital divide exists even among marginalised as do categorical differences because women are conditioned to accept and continue male dominance in subtle ways. Augmenting the efforts to provide digital literacy and competency to marginalised women may turn out to be real game changer in bringing about social change.
Indian media: How bias and fake news originate from the country’s politics
Authors: Buroshiva Dasgupta
Published: February 2023

With 1000 TV channels, 100,000 registered publications, a few hundred languages and dialects and with the growing millions of internet users, India becomes a difficult country for the authorities to ‘regulate’ the media, however hard it might try. However, in a democratic country where media is supposed to be free, the ruling party adopts other means to reign in the media. Business tycoons, close to the ruling party, buy over many of the media houses; digital teams are hired by the political parties to create fake news and trolls. The politics of the country has become essentially polarized. The new media digital technologies add to this polarization. Unlike in the west, media’s own attempts to keep itself free from fake information are limited. Consequently, the credibility of Indian media is at stake.
Polemics on the Ethno-political Narratives of the Disputed Political and Territorial Affiliation of the Crimean Peninsula
Authors: Vladimir Kushnireno
Published: February 2023

The Crimean Peninsula continues to be at the center of the conflict between Russia and Ukraine in the post-Soviet space. The relevance of this conflict increased further after the annexation of the Crimean Peninsula by the Russian Federation. The Crimean problem is extremely complex and has several dimensions: ethno-political, political & legal, economic, associated with various stages of its formation (prehistory, history, and current state). The article focuses on one of the less-studied aspects of the Crimean challenge, namely the initial stage of the evolution of the problem related to emerging the key prerequisites for the formation of contemporary ethno-political narratives about the political and territorial affiliation of the Crimean Peninsula.
Beware of the Slinking Dragon
Authors: Ashoke Mukhopadhyay
Published: February 2023

In the current political discourses of the parties as well as non-party forces, fascism has become the oftenest quoted epithet to describe the Indian panorama under BJP’s rule. During the 1970s, in the wake of the first major split in the Congress, rise of Indira Gandhi as the supremo within the Congress, and then during the days of the Emergency, talks of fascism had become a regular agenda. Thereafter, emergence of regional parties as opposition to the Congress, many non-Congress Governments coming to office in various states and on several occasions, decline of the Congress as the biggest national party, pushed the talk of fascism behind the public arena (right or wrong, whatever one may think). Recently, following the ascent of BJP to the Union Government in 2014, with special reference to the premiership of Narendra Modi, the notorious organizer of the gruelling bloodbath of the Muslims in Gujarat, the talk has returned with louder voice.
The Paradox of Closeness and Distance in a Family Science Interactive Video Conferencing Seminar: Lessons for Teaching in a Time of COVID-19 and Beyond
Authors: Sharp Elizabeth , Brooks-Hurst Erika , Velez-Gomez Paulina , Fang Dan , Nickles Debbie , Oblad Tim , Parker Andrea , Samtani Stabdi , Yuan Shu
Published: February 2023

Technological advances have created a myriad of possibilities for university teaching, administration, and research. In particular, the internet makes it possible for teaching and meetings to occur when faculty and students are in different locations, and the use of such technologies has seen an unprecedented upsurge since the COVID-19 pandemic. In this paper, we explore a Family Science graduate seminar taught by an instructor 5000 miles away from the students (n= 7) and a teaching assistant (TA) who were in the same classroom. Using a feminist pedagogical framework, we examined students, the TA, and the instructor’s reactions, emotions, and experiences during a 15-week interactive video conferencing (IVC) seminar. Focusing on discussions in the context of IVC, we share benefits and challenges and offer recommendations for using IVC. This paper contributes to the timely dialogue about discussions and emotions in teaching synchronously online and explores the possibilities and limitations of IVC teaching.
CONTENT AND COMPOSITION OF FREE AND BOUND AMINO ACIDS IN THE URINE OF CHILDREN WITH UNDIFFERENTIATED CONNECTIVE TISSUE SYNDROME LIVING IN THE REPUBLIC OF SAKHA (YAKUTIA)
Authors: M.A. Nokhsorova , N.V. Borisova , A.M. Ammosova
Published: February 2023

The article presents the results of a study using gas chromatography-mass spectrometry of the amino acid composition of urine in children with the syndrome of undifferentiated connective tissue dysplasia, living in permafrost conditions of the Republic of Sakha (Yakutia). Connective tissue dysplasia (CTD) is associated with complex metabolic changes, including amino acid metabolism. However, currently available data are conflicting. Therefore, the purpose of this study was to study the level of amino acids in the urine of children with undifferentiated CTD. Materials and methods. The present study included 48 children who were in the control group and 57 children with undifferentiated CTD included in the experimental group. The level of amino acids in the urine was assessed using gas chromatography with an Agilent GC 7820/MSD 5975 mass spectrometric detector. Statistical analysis was performed using the SPSS version 22 software. Results and discussions. The analysis of amino acids in urine makes it possible to assess their qualitative and quantitative composition, to obtain information about the existing imbalance, which may indicate nutritional and metabolic disorders that underlie a large number of diseases, including disorders associated with connective tissue. It is concluded that the increased excretion of various amino acids in the urine in children with undifferentiated CTD may be due to a violation of protein synthesis as a result of the absence (or lack) of any amino acids in the diet.
RADIONUCLIDE PERFUSION STUDIES OF THE MYOCARDIUM WITH POSITRON-EMITING RADIONUCLIDES: A REVIEW
Authors: A.A. Yurchenko , V.P. Sorkina , A.K. Kondakov , A.V. Sozykin , N.A. Novikova , M.V. Burceva , I.A. Znamenskiy , A.V. Butenko
Published: February 2023

Non-communicable diseases, coronary heart disease has ranked first among the causes of morbidity and mortality according to WHO over the past decade and a half in most developed countries. Molecular imaging techniques make it possible to detect this disease at an early stage, determine the prognosis, risks and the need for intervention. Radionuclide diagnostics can be widely used in patients with cardiac diseases to assess the viability of cardiomyocytes and myocardial perfusion and to detect the presence and extent of perfusion defects, stress-induced ischemia, and post-infarction changes using single photon emission computed tomography and positron emission tomography. Compared with foreign countries, radionuclide imaging methods are not currently widely used in cardiology practice in Russia.
This review highlights the physical foundations of single-photon emission tomography and positron emission tomography, the physiological and pathophysiological basis of radiopharmaceutical uptake in myocardial tissue, the mechanisms and procedures for performing functional pharmacological and physical stress tests, and recent data in the field of radionuclide imaging of myocardial pathology.
This review aims to acquaint the reader with the world practices of using positron-emitting radionuclides in diagnostic procedures, highlighting both their basic principles and the latest achievements in this area. The review focuses on the practice of using 82Rb in the assessment of myocardial perfusion, including in comparison with other positron-emitting radionuclides, as one of the promising areas of development in the diagnosis of coronary heart disease.
THE CONSEQUENCES OF THE NEW CORONAVIRUS INFECTION SARS-COV-2 IN STUDENTS ENGAGED IN PROFESSIONAL AND AMATEUR SPORTS
Authors: N.V. Aksyutina , O.N. Muravyova , V.A. Adolf , G.S. Savolaynen , T.Yu. Bolshakova , V.A. Kozin , V.A. Shulman
Published: February 2023

Modern people identify the concept of health and the impact of sports on life. The new coronavirus infection SARS-CoV-2 made significant adjustments to everyday student sports life. The purpose of the study: To study the impact of the new coronavirus infection SARS-CoV-2 on the physical health of students involved in professional and amateur sports. 110 students were examined, among them 62 undergraduates are professional athletes, and 48 undergraduates do amateur sports. Physical load was aerobic. Blood pressure was being measured. ECG, and the level of SaO2 were being recorded. The questionnaire was filled out using Google Forms. Statistical analysis was carried out using the Microsoft Office Excel 2017 software package and Google Forms. The results of the conducted functional examination methods for all students did not exceed the normal parameters. 39 undergraduates from 110 examined students (35.45%) experienced new coronavirus infection SARS-CoV-2. Students, who made the Gam-COVID-Vac vaccine, got ill statistically significantly less than students did without vaccination (29.76% versus 53.85%, p=0.025). We found out the certain correlation, which confirms the following. Students who do professional sports, have adverse reactions to vaccination (r=0.523; p=0.001), as well as they cope with the infection harder (r=0.370; p=0.001). In vaccinated professional athletes, the severity of the course of coronavirus infection was associated with the presence of adverse reactions to vaccination (r=0.320: p=0.016). The deterioration of physical fitness in the post-COVID period correlated with professional sports (r=0.389; p=0.016). Chest discomfort in professional athletes - smokers after infection was associated with the fact of smoking (r=0.221; p=0.014). Conclusions: Gam-COVID-Vac vaccination prevents SARS-CoV-2 new coronavirus infection in students, who do either professional or amateur sports. Professional athletes had weak toleration to Gam-COVID-Vac vaccination. In fact, if a student had adverse reaction to vaccination, he coped with the disease worse in case of infection. The deterioration in physical wellness after experienced coronavirus infection directly correlated with professional sports. Tobacco smoking worsens the course of the post-COVID period in professional athletes.
ELABORATION AND VALIDATION OF A SPECTROPHOTOMETRIC TECHNIQUE FOR ESTIMATION OF THE TOTAL FLAVONOIDS IN ANTHEMIS TINCTORIA HERB
Authors: Z.V. Kasyanov , E.A. Nepogodina , P.S. Mashchenko
Published: February 2023

The aim of this work is development and validation of a spectrophotometric technique for quantification of total flavonoids in terms of rutin in potentially medicinal plant Anthemis tinctoria herb. According to the literature, Anthemis tinctoria is used in folk medicine as a hepatoprotective, hemostatic and means, and its extracts in the experiment exhibit antimicrobial, cytostatic and antioxidant activities. In this work, we used sample of Anthemis tinctoria herb harvested in the summer of 2021 during the period of mass flowering in vicinity of Perm city (valley of the Vasilievka river, Adishchevo railway station). The raw materials were dried at room temperature, with sufficient ventilation, without direct exposure to sunlight, stored separately from other types of raw materials. According to the experiments the optimal conditions for determining of total flavonoids: grinding the raw material to a size passing through a sieve with a diameter of 1 mm, the optimal concentration of ethyl alcohol extractant is 50%, the analytical wavelength is 410 nm, the extraction time in a boiling water bath is 45 minutes, the ratio of extraction and complexing agent - 2% alcohol solution of aluminum chloride - 2:5. The technique was validated in accordance with the requirements of State Pharmacopeia of Russia 14th edition, the relative error of determination with a reliable probability of 95% was 4.00%. The technique can be used in further work to conduct studies of biological activity.
ETIOPATOGENETIC TREATMENT OF CHRONIC MIDDLE LIP CRACK IN SUBARCTIC CLIMATE
Authors: L.I. Isaeva , E.G. Borisova
Published: February 2023

Chronic crack of the lip has a high prevalence among young people in subarctic climates. The disease relapses and remissions. Linear cracks on the lips cause pain, discomfort, defects, aesthetics, cracks are completely constantly observed without complex treatment and prevention during exposure to adverse environmental conditions. The meteorological factor is a trigger mechanism for the development of chronic recurrent lip cracks in the subarctic climate. Cold wind and high sweetness destabilize the barrier function of the lip epithelium, reduce the activity of intercellular lipids. The study involved 68 male patients aged 18 to 28 years with an established diagnosis of chronic recurrent lip crack. In patients, adverse meteorological conditions were carriers of etiological diseases according to the anamnesis. At the primary medical appointment, the doctor treated chronic cracks with 0.05% chlorhexidine bigluconate, took an anamnesis, and took a complete blood count. Patients were divided into 3 groups of average manifestations of diseases (defect size, duration and nature of the manifestation). Within 14 days, patients had to adhere to the local therapy plan: group 1 used a cream based on 0.1% mometasone for 7 days, cocoa butter 3 times a day for the next 7 days, group 2 - the use of 20% propolis ointment 2-3 times a day, group 3 - local sea buckthorn oil 5 times a day. All patients were given recommendations and prescribed vitamin therapy for 2 months: AEvit and Combilipen. The subjects were tested to determine the interest in treatment on the 7th day. We evaluated the results of treatment on days 7, 14 and 30. Based on the results of the study, we concluded that, regardless of the interest in treatment, the best results were shown by treatment according to the group 1 scheme with the use of glucocorticoids. The rest of the study participants had results ranging from complete epithelialization and remission to no sign of improvement, depending on the level of interest in treatment. The treatment of a chronic lip crack requires an individual and comprehensive approach and the patient's obligatory interest in treatment. Patients should definitely use lipids as part of hygienic lipsticks during the remission period. This local prophylaxis helps restore the lipid matrix of the stratum corneum and maintain the lipid barrier of the red border of the lips from the effects of adverse meteorological factors of the subarctic climate.
ANALYSIS OF THE LEGAL REGULATION OF THE DETERMINATION OF THE DISPENSING CONDITIONS OF UNREGISTERED MEDICINES IN THE RUSSIAN FEDERATION
Authors: A.A. Semenova , A.Kh. Gaisarov , I.V. Kononova , G.Ia. Ibragimova
Published: February 2023

Currently, some aspects related to the determination of specific dispensing conditions of unregistered medicines remain insufficiently detailed by the current legislation. The aim of the study is to analyze the legal regulation of the determination of the dispensing conditions of unregistered medicines in the Russian Federation which are imported for the purpose of providing medical care to specific patients. The texts of regulatory legal acts of the Russian Federation, information from the instructions for the medical use of medicines in accordance with the online version of the state register of medicines have been used in this study. It has been analyzed that the specific dispensing conditions of medicines are determined by the Ministry of Health of the Russian Federation during their state registration, and subsequently, if appropriate reasons arise, they can be changed. It has been shown that at present, for medicines registered in the Russian Federation, there are the following main dispensing conditions, which can be arranged in the order of their tightening: over-the-counter, by prescription, only in hospitals, for special purposes. It has been established that the current legislation of the Russian Federation does not regulate in detail the dispensing conditions of unregistered medicines imported into the Russian Federation to provide medical care to specific patients for health reasons. It has been proven that, in accordance with the criteria for classifying medicines as specific dispensing conditions, these medicines cannot be over-the-counter medicines, because in any case, they require control over their use by medical professionals. The main difficulty lies in directly determining whether a particular unregistered medicine can be dispensed to a patient or his legal representatives for treatment at home, or whether it should be used exclusively in a hospital has been presented. The necessity of developing a set of organizational and legal measures that ensure the legality, safety and effectiveness of therapy with the use of unregistered medicines, both at home and in hospitals, have been substantiated, which will minimize errors in such pharmacotherapy.
PREPARATION OF STUDENTS OF PEDAGOGICAL UNIVERSITIES FOR CIVIL AND PATRIOTIC EDUCATION
Authors: L.I. Ponomareva , N.Yu. Gan
Published: February 2023

The current situation that has developed in the education system is characterized by great attention to the problems of citizenship and patriotism of young people. In addition, work is actively underway to develop a system of civil and patriotic education in pedagogical universities of the country.
At the socio-pedagogical level, this problem comes to the fore for several reasons: the process of democratization contributes to the formation of a multiparty system in which the younger generation should be guided; a huge amount of information requires a selective attitude and understanding of the conjuncture; the political situation in the country and the world places high demands on young people for knowledge of their history, respect for traditions and civil position. That is why the reform of modern education requires the creation of a well-functioning system for the formation of civil-patriotic qualities of the individual, taking into account the principles of a humanistic nature.
The Federal Law “On Education in the Russian Federation" establishes the principles of "the humanistic nature of education, the upbringing of mutual respect, diligence, citizenship, patriotism, responsibility, legal culture, respect for nature and the environment, protection and development of ethno-cultural characteristics and traditions of the peoples of the Russian Federation in the conditions of multinational state” [1].
During the preparation of students for professional activities, it is necessary to pay attention to the development of their personal qualities: diligence, courage, creativity in decision-making, respect for the history of the country and people who left their mark on history.
A generalizing analysis of psychological and pedagogical studies of the problem shows that starting from the first level of education - preschool childhood, ending with the highest level - training of personnel, it is required to solve the tasks of developing a civic-patriotic position.
This article presents a study that reveals the potential of the created system of civil and patriotic education of students on the example of a particular university, Shadrinsk State Pedagogical University.
THEORETICAL APPROACHES TO THE STUDY OF SOCIAL INTELLIGENCE
Authors: E.V. Pagaeva , M.V. Vereshchagina
Published: February 2023

The work is devoted to the actual problem of studying social intelligence as a socio-psychological construct that influences the processes of modeling effective communication and achieving goals in activities. Based on the purpose of the study, which is to review theoretical approaches to the study of social intelligence, a description is given of the main scientific approaches to understanding the content of social intelligence: general psychological, factor-analytical, psychometric, structural-genetic, cognitive and ethno-psychological. The analysis made it possible to single out common essential grounds in understanding the content of social intelligence: as a complex general ability, characterized by structure and a set of cognitive, emotional and behavioral components, the subject of which is the prediction of one's own actions and the actions of other people in various situations of interaction; as a personal education associated with the performance of certain activities and the level of development of general intelligence. Particular attention is paid to the ethnopsychological approach to the study of social intelligence, which is due to scientific interest in the problem of ethnocultural characteristics of social intelligence. The influence of the social environment, including the ethnic community, within which the socialization of the individual takes place, on the development of social intelligence is emphasized. It is noted that social thinking and social representations and laws, stereotypes, cognitive schemes established in society have an impact on the formation of a person's social intelligence. The article provides the author's understanding of social intelligence as a structural psychological formation that contributes to the socialization of the individual, ensures adaptation in society and influences the effectiveness and success of social interaction. The functions of social intelligence are also given: cognitive-evaluative, communicative-value and reflective-corrective. The applied significance of the results of this study is to substantiate the initial positions of the authors to develop an empirical research program to study the ethnocultural characteristics of social intelligence.
FORMATION OF THE GENEALOGICAL CULTURE OF THE INDIVIDUAL IN THE EDUCATION SYSTEM OF THE REPUBLIC OF SAKHA (YAKUTIA): EXPERIENCE AND PROBLEMS
Authors: N.D. Krylova , G.S. Popova
Published: February 2023

The relevance of the issue of identifying the genealogical self among all the population of the country is the requirement of post-Soviet period. Now it is time to pass this vital need of all the gained experience by current generation to next. Is 30 years enough to rooting genealogical culture of the nation? Are young parents and families aware of how to teach genealogical competences their children? The same questions are on the agenda of our education system. Taking into consideration the mentioned questions, this study aims to analyze the state of public education system and the family institution in terms of the questions about formation and developing the genealogical culture of personality. To achieve the aim of the study, the authors used traditional general scientific methods applied in humanitarian fields: a review of literature and sources, sociological methods, logical analysis, analogy, generalization, systematization. The results showed that the process under study based on the research goes to a greater extent by itself, without a purposeful, strategic approach to this most important area of inculturation of growing members of society, mainly due to the aggravated urgency of the problem. The practical significance and, to some extent, the theoretical value of the article lies in the consideration of the methodological side of solving the problem the authors attempted to answer the question "How to form?" genealogical component of personal culture.
RESULTS OF THE REGIONAL STAGE OF THE ALL-RUSSIAN OLYMPIAD IN BIOLOGY IN THE CHUVASH REPUBLIC IN 2016-2022
Authors: E.V. Saperova , V.V. Alekseev
Published: February 2023

Olympiads of schoolchildren play an important role in identifying the most talented students, motivate them to study the discipline in depth, develop a creative approach to solving non-standard tasks, and play a leading role in the formation of highly professional scientific personnel of the country. The faculty of natural science education of Yakovlev University has been participating in the organization and holding of the regional stage of the all-Russian olympiad of schoolchildren in biology since 2016 and is the basis for organizing training camps. The analysis of the results of the regional stage of the all-Russian olympiad of schoolchildren in biology in the Chuvash Republic during this period will allow to adjust the system of teaching schoolchildren and increase the effectiveness of participation in the olympiad. The purpose of this study is to study the results of the regional stage of the all-Russian olympiad of schoolchildren in Biology in the Chuvash Republic in 2016-2022. Materials and methods. The analysis of the effectiveness of the performance of schoolchildren of the Chuvash Republic in the stages of the olympiad in biology was carried out on the basis of data obtained during the stages of the olympiad in biology by the chairman and members of the jury, as well as provided for analysis by the center «Etker» of the Ministry of Education of Chuvashia. Data analysis was carried out using the program and Statistica 7.0. Results. The paper presents the experience of the regional stage of the all-Russian olympiad of schoolchildren in biology in the Chuvash Republic in 2016-2022 and the prospects for improving the effectiveness of the participation of schoolchildren at the final stage. The analysis of the data showed that starting from 2018 to 2020, the proportion of students completing tasks in both theoretical and practical rounds has significantly increased. The decrease in the percentage of correctly completed tasks in 2021 and 2022 can be attributed to the fact that in these years the training camps were held more in a remote format, the regularity of school attendance depended on the students being in quarantine, in addition, there was no possibility of inviting the jury members of the final stage to prepare students for the regional stage of the all-Russian olympiad.