bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect Of Organizational Support On Work Satisfaction In Regional Secretariat Employees In Pariaman District
Authors: Saputra Nika
Published: February 2020

Human resources are one of the resources that exist in a company besides other resources, for example capital, materials, machinery in the company, so that it becomes useful. For this reason, companies are beginning to strive to excel in such competitive competition by trying to create quality and presentative human resources. This study aims to provide evidence that to determine whether or not there is an influence of organizational support on the work satisfaction of the Regional Secretariat Staff in Pariaman Regency. Data collection is done by survey method with a questionnaire. The data analysis technique used in this study is descriptive and quantitative analysis. The data collected is primary and secondary data which can be classified as independent variables and dependent variables. Organizational Support (influence variable), and Job Satisfaction in Regional Secretariat Staff of Pariaman Regency (affected variable). Testing the hypothesis in this study using a simple linear regression test. Based on the results of the study, it is known that there is a positive and significant influence between organizational support for and Job Satisfaction in the Regional Secretariat Staff of Pariaman Regency, obtained by a calculation that is greater than the Ttable where 2.806> 2.015 with a significance of 0.007 <0.05.
Applying Rigor to Agile Research and Innovation Projects Guided by Product Development
Authors: Tejero Alberto , León Gonzalo
Published: February 2020

This article, as a main contribution, shows a new agile way to manage and monitor R&I projects, by monitoring product development. In addition, a new way of calculating the rigor of this type of projects is presented using the “3D rigor method”, based on obtaining the rigor measures of the product, process and reputation of the project researchers. Thanks to this new method, it is possible to know the rigor of an R&I project at any time during its development, which enables its monitoring and management to adapt it to the interests and needs of each situation. On the one hand, this method is presented as a tool of great utility for new researchers, since it will allow them to guide the development of their R&I project in an agile way, adjusted to the speed of the current times, while maintaining minimum levels of rigor and scientific quality. On the other hand, the method is highly recommended for all those organizations that promote and support the development of new R&I projects, enabling them to mentor and guide the projects towards the achievement of specific objectives and viable projects.
Factors influencing on salesperson performance in information service industry
Authors: Linh Nguyen Thi Thuy
Published: February 2020

To examine major factors that influencing on salesperson performance in information service industry, especially academic publishing and data analytics companies, researcher proposed research model and hypotheses. A full measurement model was tested by CFA analysis and modeling procedure. Then, structural equation model was tested. Models fit the data well. Proposed hypotheses were supported and interpreted. Factors influencing on salesperson performance in information service industry, especially academic publishing and data analytics companies includes adaptive selling behavior, customer orientation, guanxi. It’s found that customer orientation, adaptive selling behavior, “ganqing” (apart of “guanxi”) has positive influence on salesperson performance, whereas “renqing” (apart of “guanxi”) has positive to adaptive selling behavior, but not support salesperson performance. Besides, customer orientation is proved to have strong positive impact on adaptive selling in relationship toward salesperson performance in this industry. Not only the customer orientation but the relationship between salesperson and his buyer's representatives have strong influence on his selling behavior and performance. The social relationship between salesperson and his customer's representative have strong affect on salesperformance than his adaptive selling behavior and customer orientation. It's the implication for manager to encourage their salespeople to develop emotional attachment among parties networking in order to improve their salesperson performance strategically. The research also affỉrmed the significance of customer orientation on adaptive selling behavior, toward their positive influence on salesperson performance in information industry, especially academic publishing and data analytics companies. It then suggested salesperson consider the effects of favors exchanges or reciprocity with his business partner. Therefore, sales manager can identify and orient salespeople the relevant treatment strategy for their customers, in order to improve sales performance.
Properties and genesis of soils in the Balagansk forest-steppe of Central Siberia and their ecological and resource potential
Authors: Martynova Natalia A. , Vlasova Victoria Yu.
Published: February 2020

The aim of the study. To study the properties and genesis of natural soils of forest-steppe areas of Balagansk steppe.
Location and time. The environs of Balagansk settlement in the Balagansky district of Irkutsk region, 2013-2018.
Methodology. Combined field and laboratory studies of soil cover and soil properties using soil-morphological, pedo-lithological, climatostratigraphic, botanical, geological-geomorphological and comparative geographical methods, as well as various physical and chemical analyses.
Main results. The study of soil properties of the Balagansk’ forest-steppe and assessment of their classification position revealed the basic regularities of geographical distribution of soils. In steppe areas of the studied region clay-illuvial and textural-carbonate chernozems were formed. The forest vegetation favoured the developed of residual-carbonate gray, dark gray, gray and dark gray metamorphic and burozemic soils; the floodplain areas are predominantly occupied by gley soils and dark-humus gleic soils.
Conclusion. The study of soil and vegetation cover of the Balagansk’ forest-steppe showed that soils were developed on the eluvium-deluvium of carbonate Cambrian red-colored siltstones and loess cover and have sufficiently high natural fertility and ecological and resource potential. The soils of the investigated area are characterized by a large variety and complex polygenetic structure of the soil profile, which reflects the change of soil formation’ conditions during Holocene-Pleistocene.
La inserción profesional docente en Colombia:
Authors: Jiménez Maria Mercedes
Published: February 2020

El propósito de este artículo es presentar elementos generales de la política sobre formación de docentes en Colombia y especialmente, concentrarnos en la inserción profesional docente. El interés en esta etapa surge desde hace varios años en el mundo, sin embargo, en Colombia es un tema asociado al seguimiento de egresados o a las jornadas de inducción y todavía no aparece en los documentos de política. Por ello, se mencionan algunas iniciativas locales y nacionales, las cuales muestran que es posible atender a este grupo de maestros, que están en sus primeros años de ejercicio docente, enfrentándose a situaciones personales, institucionales y sociales, de manera solitaria y frustrante o llevando en algunos casos, a la deserción de la profesión. Se incluye parte de la revisión de literatura que hemos realizado en varios proyectos del Grupo PiEnCias, así como avances de procesos de acompañamiento que desarrollamos desde el 2015.
Formación de profesores en Uruguay
Authors: Zidán Eduardo Rodríguez , Silva Javier Grilli , Rodríguez Soledad Rodríguez
Published: February 2020

O Uruguai iniciou nos últimos anos um complexo processo de renovação na formação de profissionais da educação. Nesse sentido, a transição para a formação de professores de natureza universitária destaca o conflito entre tradições formativas e as novas demandas das políticas de professores que buscam repensar as habilidades, conhecimentos e condições de trabalho exigidos pelos professores. Este relatório visa aprofundar o processo atual de transformação do modelo de formação de professores do ensino médio no Uruguai, sob uma perspectiva histórica e analítica. A abordagem deste processo é realizada a partir de uma dupla via de análise. Por um lado, estudam-se a gênese e os principais marcos da formação de professores do ensino médio no Uruguai. Paralelamente, refletimos sobre as principais tensões e conflitos que surgem da análise da implementação de políticas educacionais e as diferentes posições e conflitos entre autoridades administrativas, sindicatos e diferentes grupos de ensino. Entre outros aspectos que geram tensões e conflitos na história da formação de professores no país, refletimos sobre o debate em torno do desenho de planos curriculares, regulamentos de processos de formação e práticas de formação de professores.
A difusão da cultura negra e sua interface na formação de professores da EJA
Authors: Silva Marcelo Donizete , Quirino Katia Maria dos Santos
Published: February 2020

Este artigo tem como objetivo, contribuir com a análise acerca produção de um material didático crítico, acerca da cultura negra trabalhada no contexto escolar de Mariana-MG. Intitulada “A difusão da Cultura Negra e sua interface na Formação de Professores da EJA: uma análise sobre as questões étnico-raciais nas escolas de Mariana”, o objeto da análise far-se-á a partir da investigação sistemática dos materiais pensados e propostos, ao que é referente às questões étnicos-raciais, para Educação de Jovens e Adultos (EJA).  Para esse fim propôs-se também, analisar sobre os fundamentos, ideológicos, das terias educacionais contemporâneas no que pesa a influência destas na formação de professores e dos jovens das escolas periféricas. Nesse sentido, essa pesquisa terá como base teórica uma perspectiva de cunho crítico que envolve as áreas da Formação de Professores, Epistemologia e teorias educacionais e História da Educação do Negro no Brasil.
Revisitando las escuelas normales en Chile
Authors: Silva-Peña Ilich , Olivos-González Fernanda , López-Torres Lorena P.
Published: February 2020

A mediados de los 70 en Chile se vivió una drástica transformación económica,  política y cultural. En el campo de la formación de docentes para escuelas primarias, desde fines de los 60 se proponía un cambio traspasando esa labor desde las Escuelas Normales a la formación universitaria. Un proceso que se aceleró con el golpe militar del 11 de septiembre de 1973. Desde aquel tiempo que la investigación sobre las escuelas normales ha continuado, de manera general, desde una perspectiva historiográfica y a través de la recopilación de relatos. Ahora, luego de una serie de transformaciones en la formación docente en nuestro país, proponemos avanzar hacia el rescate de las formas, contenidos y valores que se reforzaban en aquellos años. En esa búsqueda, encontramos que los conceptos de democracia, participación, ciudadanía, activismo y justicia social estaban presentes en la formación normalista. Este artículo propone un trabajo de reencuentro con la historia de la formación docente realizada en las Escuelas Normales para, a través de su revisión, analizar los nuevos desafíos que interpelan a la docencia en el Chile de hoy.
Primera experiencia de formación de profesores en el norte del Perú
Authors: Robles Ortiz Elmer
Published: February 2020

RESUMEN: El presente texto aborda la creación y desarrollo de la primera Escuela Normal Urbana de Trujillo y del norte del Perú, nacida al interior de la Universidad Nacional de esta ciudad, el año de 1936, destinada a la formación de profesores de educación primaria y secundaria. El problema planteado consiste en dilucidar la diferencia en las iniciativas de la creación de escuelas normales de Lima y de Trujillo. El trabajo comienza haciendo referencia a la fundación de las primeras escuelas normales en Lima, por disposiciones del gobierno central durante los siglos XIX y XX. Luego se investiga los antecedentes o primeras tentativas en Trujillo para establecer los estudios conducentes a la formación de educadores, que confluyeron en la creación de la Sección Pedagógica el año de 1936, matriz de la Escuela Normal en sus ramas de Normal Urbana y Normal Superior, en el seno de la hasta entonces única universidad en Trujillo y en la región norteña. Asimismo se alude a su organización, plan de estudios y especialidades, así como a sus directivos y primeros egresados. La investigación continúa con la creación de la Facultad de Letras y Educación dentro de la cual quedó inmersa la Escuela Normal a partir de 1946 hasta su cierre en 1972. Se demuestra que en la capital de la república y otras ciudades, las escuelas normales del siglo XIX y aún del XX fueron fundadas por disposiciones del gobierno central, en tanto que en Trujillo la decisión es de carácter local. Para nuestra investigación fueron consultadas fuentes primarias –archivos y otros documentos- como también secundarias. Hemos contado con los aportes de autores individuales e institucionales.
Douleur postopératoire en chirurgie hémorroïdaire
Authors: Vinson-Bonnet B.
Published: February 2020

La douleur après hémorroïdectomie est une préoccupation importante pour les patients et mérite à ce titre une prise en charge spécifique. La douleur est plus importante après hémorroïdectomie tripédiculaire qu’après technique mini-invasive. La prise en charge comprend trois étapes pré- per- et postopératoire. L’information préopératoire est un élément essentiel qui conditionne en partie le recours aux antalgiques. Le bloc pudendal est l’élément clé de la prise en charge de la douleur postopératoire immédiate. La douleur lors de la première selle doit être anticipée par la prise d’antalgiques. L’analgésie postopératoire qui repose sur les analgésiques non opiacés, ceux-ci n’étant administrés qu’en recours, doit être anticipée et codifiée.
LA PARTICIPACIÓN CIUDADANA EN VENEZUELA Y ECUADOR EN EL ÁMBITO MUNICIPAL. COMPARACIÓN CONSTITUCIONAL Y LEGAL
Authors: Castellanos Herrera Silvio José
Published: February 2020

El desarrollo constitucional después de la segunda guerra mundial, muestra claramente un salto significativo sobre el papel tradicional de la sociedad civil, en la función administrativa del gobierno, que de manera exclusiva le estaba atribuida a este último. Los cambios que van desde el neo constitucionalismo, hasta el nuevo constitucionalismo latinoamericano, pasando por una larga historia de vaivenes relativos a la inclusión del pueblo en la gestión y control de la acción gubernamental, se muestran en este trabajo, a través de una revisión bibliográfica, en el contexto de la dupla insoslayable poder-derecho y la garantía constitucional, “participación ciudadana” en la administración municipal, previstos en las cartas magnas e instrumentos legales de Venezuela y Ecuador; esto con el objetivo de resaltar las semejanzas, similitudes y realidad asociada a la evolución de la integración del poder constituyente en el poder constituido, en cuanto a gestión de gobierno local se refiere, para llegar finalmente a proposiciones concretas sobre los particulares comentados, que permitan una verdadera superación del status que mantiene alejada a la comunidad de la gestión municipal.
FORMULASI MASKER GEL PEEL OFF DARI EKSTRAK ETANOL UMBI BAWANG DAYAK (Eleutherinebulbosa (Mill.) Urb. Eleutherine americana Merr)
Authors: Kartikasari Dian , Anggraini Reni
Published: February 2020

INTISARI   Umbi bawang dayak memiliki kadar antioksidan yang sangat tinggi. Penelitian ini bertujuan mendapatkan formula masker gel feel off ekstrak umbi bawang dayak yang menghasilkan pembentukan film yang baik berdasarkan hasil evaluasi fisik. Masker gel peel off dibuat dalam 3 formula dengan parameter perbedaan konsentrasi PVA. Formula 1 PVA 10 %, formula 2 12%, formula 3 PVA 13%. Proses pembuatan ekstrak dengan cara maserasi, kemudian dipekatkan dengan evaporator dan dibuat sediaan masker gel peel off dengan penambahan eksipien. Hasil uji organoleptis menunjukkan parameter aroma, warna dan tekstur tidak berbeda nyata antar formula. Hasil uji fisik menunjukkan formula 3 dengan PVA 13 % menghasilkan masker gel peel off yang paling baik dibandingkan dengan formula 1 dan 2, dengan nilai viskositas 3,833 cps, pH 6, homogeny, waktu mongering < 15 menit dan uji daya sebar 5, 815 cm. Kata kunci: bawang dayak, masker gel peel off, PVA.   ABSTRACT   Bawang Dayak bulbs have a very high antioxidant content. This study aims to get the mask gel feel off formula the bawang Dayak bulb extract that results in good film formation based on the results of physical evaluation. The mask gel Peel off is made in 3 formulas with different parameters of PVA concentration. Formula 1 PVA 10%, formula 2 12%, formula 3 PVA 13%. The process of preparing the extract by maceration, then concentrated with evaporator and made gel mask preparation with the addition of excipients. The results of organoleptic tests showed the parameters of aroma, color and texture were not significantly different between the formulas. Physical test results showed that formula 3 with PVA 13% yielded the best peel off gel mask compared with formula 1 and 2, with viscosity value 3,833 cps, pH 6, homogeny, mongering time <15 min and spreading test 5,515 cm. Keywords: Bawang Dayak, mask gel peel off, PVA.
UJI AKTIVITAS ANTIPIRETIK EKSTRAK DAUN SISIK NAGA(Pyrrosia piloselloides (L.) M.G. Price) TERHADAP TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR WISTAR YANG DIINDUKSI PEPTON 5%
Authors: Widyasari Ratna , Yuspitasari Dina , Fadli Fadli , Masykuroh Athiah , Tahuhiddah Winda
Published: February 2020

INTISARI  Demam adalah keadaan ketika suhu tubuh meningkat melebihi suhu tubuh normal. Demam terjadi karena pelepasan  pirogen  dari dalam leukosit yang sebelumnya telah terangsang oleh pirogen  eksogen yang dapat berasal dari mikroorganisme atau merupakan suatu hasil reaksi imunologik yang tidak berdasarkan suatu infeksi. Sementara itu, banyak  negara telah mengembangkan pengobatan menggunakan herbal. Salah satu usaha yang dilakukan adalah dengan penggunaan obat tradisional. Penelitian ini bertujuan untuk membuktikan bahwa daun Sisik Naga (Pyrrosia piloselloides  (L.) M.G Price) dengan konsentrasi 0,062%, 0,125% dan 0,25% memiliki aktivitas antipiretik dengan menggunakan penginduksi demam  Pepton  5%. Penelitian ini merupakan penelitian eksperimental dengan Rancang Acak Lengkap (RAL). Pengukuran suhu rektal tikus menggunakan termometer  infra red. Hewan uji dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif (suspensi Na-CMC 1%), kelompok kontrol positif (suspensi parasetamol) dan kelompok uji yaitu pemberian ekstrak daun sisik naga 0,062%, 0,125% dan 0,25%. Data yang diperoleh dianalisis dengan  menggunakan uji anova dan uji LSD (Least Significant Different). Hasil dari penelitian ini bahwa ekstrak daun sisik naga (Pyrrosia piloselloides  (L.) M.G Price) konsentrasi 0,25% mempunyai aktivitas antipiretik pada tikus putih (Rattus norvegicus) jantan galur wistar. Kata kunci: Antipiretik, Daun Sisik Naga (Pyrrosia piloselloides (L.) M.G Price), Pepton 5%   ABSTRACT  A fever is a condition when the body temperature rises beyond the normal body temperature. Fever occurs due to the release of pyrogytes from within leukocytes that have previously been stimulated by exogenous pyrogens that may originate from microorganisms or are a result of immunologic reactions that are not based on an infection. Meanwhile, many countries have developed treatments using herbs. One of the efforts done is with the use of traditional medicine. This study aims to prove that the leaves of the Dragon Scales (Pyrrosia piloselloides (L.) M.G Price) with concentrations of 0.062%, 0.125% and 0.25% have antipyretic activity using Pepton fever induction 5%. This research is an experimental research with Completely Random Design (RAL). Rectal temperature measurements of mice using infra red thermometer. Test animals were divided into 5 groups: negative control group (1% Na-CMC suspension), positive control group (paracetamol suspension) and the test group were 0.062%, 0.125% and 0.25%. The data obtained were analyzed using anova test and LSD (Least Significant Different) test. The results of this study showed that the extract of leaf scales (Pyrrosia piloselloides (L.) M.G Price) concentrations of 0.25% had antipyretic activity in white rats (Rattus norvegicus) male wistar strain. Keywords: Antipyretics, Leaf Scales Dragon (Pyrrosia piloselloides (L.) M.G Price), Pepton 5%
Efek Antihipertensi Ekstrak Etanol Kombinasi Rambut dan Biji Jagung (Zea mays L.) pada Tikus Hipertensi yang Diinduksi Monosodium Glutamat
Authors: Anas Yance , Hatimah Naimi Amalia
Published: February 2020

INTISARI  Penelitian sebelumnya membuktikan bahwa infus rambut dan jus biji jagung memiliki efek antihipertensi pada tikus jantan sehingga dapat dikembangkan dalam bentuk ekstrak. Penelitian ini bertujuan untuk membuktikan efek antihipertensi ekstrak etanol kombinasi rambut dan biji jagung (EEK-RBJ) pada tikus hipertensi yang diinduksi monosodium glutamat  (MSG). EEK-RBJ dibuat menggunakan metode maserasi. Tikus hipertensi dibuat dengan cara pemberian MSG 100 mg/kgBB/hari selama 14 hari sampai tekanan darah sistol   ≥  155 mmHg. Tikus hipertensi yang digunakan sebanyak 25 ekor, dibagi menjadi 5 kelompok yaitu kelompok kontrol hipertensi (CMC-Na 0,5% 12,5 mL/kgBB/hari), kelompok furosemid 5,04 mg/kgBB/hari), dan kelompok EEK-RBJ (125, 250 dan 500) mg/kgBB/hari. Sediaan uji diberikan satu kali sehari selama 14 hari (p.o). Data yang diamati adalah perbedaan tekanan darah sistol dan diastol sebelum dan setelah pemberian sediaan uji serta perbedaan penurunan tekanan darah. Data perbedaan tekana darah dianalisa secara statistik menggunakan uji t-berpasangan atau  uji  Wilcoxon  (P: 0,95). Hasil penelitian menyimpulkan bahwa EEK-RBJ (125, 250 dan 500) mg/Kg BB/hari selama 14 hari mampu menurunkan tekanan darah sistol dan diastol tikus hipertensi dengan pola tergantung dosis. EEK-RBJ 500 mg/Kg BB/hari dapat menurunkan tekanan darah sistol dan diastol tikus hipertensi yang diinduksi MSG berturut-turut sebesar 20,04 mmHg dan 13,16 mmHg. Kata Kunci: Efek antihipertensi, ekstrak kombinasi, rambut dan biji jagung, MSG  ABSTRACT   In previous studies, infusion of silk and corn seed combination have antihypertensive effects, so it can develop in the form of extracts. The purpose of this study is to reveal the antihypertensive effect of a silk and seed corn ethanol extract (SSC-EE) on MSG-induced hypertensive rats. SSC-EE produced with maceration. MSG 100 mg/kg BW/day for 14 days orally used to induce hypertension condition in male Wistar rats until systolic blood pressure ≥ 150 mmHg. Twenty-five of hypertensive rats divided into five groups. Hypertensive rats in Group I treated with CMC-Na 0.5% 12.5 mL/kg BW/day and group II treated with Furosemide 5.04 mg/kg BW/day. Meanwhile, group III, IV and V treated with SSC-EE (125, 250 and 500) mg/kg BW/day. SSC-EE was treated orally once daily for 14 days. Systolic and diastolic blood pressure, before and after of extracts treatment and blood pressure decline was observed and analyzed statistically using paired t-test or Wilcoxon test (P: 0.95). The results show that SSC-EE (125, 250 and 500) mg/Kg BW/day for 14 days can decrease the MSG-induced hypertensive rats systolic and diastolic blood pressure (p<0.05) with the dose-dependent manner. SSC-EE 500 mg/Kg BW/day decrease the systolic and diastolic blood pressure of 20.04 mmHg and 13.16 mmHg, respectively. Keywords: Antihypertensive effect, combination extract, silk and seed corn, MSG
UJI SITOTOKSIK DENGAN METODE BRINE SHRIMP LETHALITY TEST DAN PROFIL METABOLIT SEKUNDER DARI EKSTRAK BIJI BUAH BERENUK (Crescentia cujete Linn)
Authors: Arel Afdhil
Published: February 2020

ABSTRACTThe purpose of this research is to find out the profile of secondary metabolite contained in the extract of seeds (Crescentia cujete Linn.) And cytotoxic test against shrimp larvae Artemia salina Leach by BSLT method. Phytochemical tests showed that the extract be expected contained the terpenoid, alkaloid, phenolic, secondary metabolite compounds. The results of qualitative analysis with positive TLC contains phenolics. The result of identification with Spectrophotometer UV-visfor determination of α max from berenuk seeds extract consisted of 3 peaks with α max 326 nm, 258 nm, 222 nm be expected terpenoid compound, alkaloid, and phenolic. The results of toxicity test using shrimp larvae (Artemia salina leach) were divided into 4 groups: 1 control group and 3 groups of concentration series. The concentration of test solution used was 1,000, 100 and 10 μg / ml. The shrimp larvae mortality was observed after 24 hours of treatment. Based on the analysis with probit method, LC50 value of seed extract berenuk to shrimp larvae Artemia salina Leach is equal to 82,30 μg/ml. This shows that the extract of berenuk berries is toxic to shrimp larvae Artemia salina Leach, presence to terpenoid content, alkaloids and phenolics in the extract of seeds berenuk.Keywords : Secondary metabolite; Cytotoxic; BSLT.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN DAN KULIT BATANG BERENUK TERHADAP Bacillus cereus
Authors: Hidayati Devi Nisa , Sumiarsih Cicih , Mahmudah Umroh , Puspitasari Anita Dwi
Published: February 2020

ABSTRACTThe plants (Crecentia cujete Linn) Are known to have antibacterial activity and can be used as a diarrhea drug due to microorganisms. Bacillus cereus is one of the bacteria that causes diarrhea.This aims to the study was antibacterial activity of ethanol extract of leaves (EL) and bark broodstock (EB) on Bacillus cereus. EL and EB were extracted with ethanol 96% using maceration method. Antibacterial activity test was carried out with disk diffusion method in EL with a concentration of 30%, 60%, 90%, 120% and 150%, and in EB using concentrations of 60%, 70%, 80%, 90% and 100% then antibacterial activity measurements were taken. by looking at the Diameter of the Inhibitory Area (DDH). The results of the EL and EB of antibacterial activity proved that EL and EB berenuk have antibacterial activity against Bacillus cereus.Keywords: Antibacterial, Crescentia cujete Linn, Bacillus cereus.
EVALUASI KARAKTERISTIK FISIKA-KIMIA SEDIAAN KRIM DAN LOTION EKSTRAK KULIT BUAH NANAS (Ananas comosus L.Merr)
Authors: Zulfa Elya , Mufrod Mufrod
Published: February 2020

ABSTRACTIn previous research, ethanolic extract of pineapple peel (EEPP) has activity as a sunscreen because of the content of flavonoids. EEPP can be formulated in the form of creams and lotions to facilitate use on the skin. This study aims to evaluate the physical chemistry characteristics of EEPP creams and lotions. Creams and lotions were made in 3 formulas based on variations in FI extract concentrations (15.0%), FII (17.5%), FIII (20.0%), base controls and positive controls (preparations on the market). The cream obtained was evaluated for physical chemical characteristics including organoleptic, homogeneity, adhesion and dispersion, viscosity, pH and SPF values which were analyzed descriptively. cream with varying concentrations of green, the distinctive smell of pineapple, homogeneous and in accordance with the pH of the skin. Increasing the concentration of EEPP in the preparation has an effect on increasing viscosity, adhesion but decreasing the dispersion. Whereas the lotion shows greenish color, aromatic odor and semisolid texture and is easily applied. The increase in EEPP in lotion affects the increase in pH, adhesion, but decreasing the dispersion.Keywords: Creams, lotions, sunscreen, pineapple fruit skin
FORMULASI SIRUP EKSTRAK ETANOL DAUN PARE (Momordica charantia L.) DENGAN GELATIN SEBAGAI PENGENTAL DAN AKTIVITAS MUKOLITIKNYA
Authors: Wulandari Ririn Lispita , Mahmud Eli , Mufrod Mufrod
Published: February 2020

ABSTRACTEthanol extract of bitter melon leaves at a concentration of 5% has been shown to have mucolytic activity. For ease of use that is made of dosage forms syrup. Thickening agent serves to increase the viscosity and resist settling process resulting in a stable syrup. Gelatin has the ability to improve settling extract better than other thickening. This study aims to determine the effect of variations in the concentration of gelatin to the physical-chemical properties and activity of ethanol extract syrup mukolitik pare leaves the cow intestine mucus in vitro. Extraction of leaf bitter melon is done by percolation. EEDP was made into three syrup formulas using 1% (FII), 2% (FIII), 3% (FIV) gelatin thickener. There is also syrup without extract and gelatin (FI) as a control. The four syrup formulas were examined for physical chemical properties (organoleptic, homogeneity, pH, viscosity), and tested their mucolytic activity. Data on the results of activity tests in the form of viscosity were analyzed by Kruskal-Wallis followed by Mann-Whitney. Data from organoleptic examination, homogeneity, Ph were analyzed descriptively, while viscosity with Linear Regression. The results showed that EEDP syrup with a gelatin concentration of 1%; 2%; 3% have mucolytic activity. The results of examination of the physico-chemical properties of FII, III, and IV syrups have the same taste and color, sweet and bitter, and are greenish black in color, while FI syrup is sweet and yellowish in color. Homogeneous FI syrup, FIII and FIV syrup are evenly distributed, while FII syrup has coarse particles. Fourth pH normal syrup formula. Increased concentration of gelatin (1%; 2%; 3%) can increase the viscosity of syrupKeywords: ethanol extract of bitter melon leaves, syrup, gelatin
TOKSISITAS AKUT INFUSA KULIT ARI KACANG TANAH (Arachis hypogea L.) PADA MENCIT BALB/ C
Authors: Fithria Risha Fillah , Wulandari Ririn Lispita , Hidayati Devi Nisa , Rejeki Lilis
Published: February 2020

ABSTRACTPeanut shell (PS) infusion has been shown to be antithrombocytopenia, but there has been no research on safety standards. This study aims to identify the symptoms of toxic effects, the potency of toxicity and histopathology of liver male Balb/C mice after a single dose of PS infusion. This research uses randomized matched posttest only control group design. Twenty five mice were divided into 5 orally dosage groups, ie, PS infusion with a dose of 0,026; 0.052; 0.104; 0.208 g/20gBW; and negative control of CMC Na 0.5%. The observation period is for 14 days. The results showed that single dose of PS infusion had a pseudo LD50 value ie > 0.208g/20gBW which was practically non toxic. Symptoms to watch out for the BW infusion were passive behavior, bradycnea, hair color change, hair loss, and weight loss at doses of 3 and 4. It is unclear whether liver damage ie inflammation, necrosis, and albuminous degeneration caused by PS infusion or other causes.keywords: acute toxicity, infusion, peanut shell
FORMULASI DAN UJI EFEKTIVITAS ANTIBAKTERI EDIBLE FILM EKSTRAK BIJI PINANG (Areca catechu Linn)
Authors: Ningsih Wida
Published: February 2020

ABSTRACTThe tannins contained in areca nut extract can inhibit the growth of Streptococcus mutans bacteria. To facilitate the use of betel seed extract as an antibacterial, it was formulated into an edible film with a concentration of 2.5%, 3% and 3.5%. Making edible films using solvent casting method and testing antibacterial activity using blood agar diffusion method. The edible film of areca nut extract made an evaluation included organoleptic, thickness, brittleness, water content, pH, and swelling test. The evaluation results of betel nut edible fim extract showed almost the same characteristics as the edible fim that had been circulating in the market which was used as a comparison. The presence of antibacterial activity from edible pinang seed extract is marked by the formation of clear zones. The test results of antibacterial edible activity of areca nut extract films 2.5%, 3% and 3.5% showed the average diameter of clear zone was 14.96 mm, 15.49 mm and 17.05 mm which were included in the strong category.Keywords: Areca catechu Linn, antibacterial, edible film, tannin, streptococcus
PENETAPAN KADAR STEVIOSIDA PADA SIMPLISIA DAN EKSTRAK DAUN Stevia rebaudiana DARI TIGA DAERAH BERBEDA
Authors: Kartikasari Dian , Nurkhasanah Nurkhasanah , Pramono Suwijiyo
Published: February 2020

ABSTRACTPharmaceutical raw materials from agriculture or collection of wild plant chemical content can not be guaranteed always constant due to variable seed, the body, the climate, the conditions (age and how to harvest). The content of the chemical compounds responsible for the biological response must have chemical specifications, namely the composition information (type and concentration). The efficacy of traditional medicine based on the chemical compound. Therefore, the assay of the active substance a crude drugs and extracts needs to be done to ensure that a traditional medicinal products can be assured of quality and usefulness. The assay performed on botanicals and 50% ethanol extract of leaves of Stevia rebaudiana. The assay of the crude drugs and extracts from the stevia leaf area of Malang, Tawangmangu, and Bogor using High Performance Liquid Chromatograph method. Results of the assay stevioside on simplicia and stevia leaf extract obtained stevioside levels in simplicia stevia leaves from Malang, Bogor, Tawangmangu consecutive namely 5.65%; 3.89%; 1.59%. Stevioside levels in the stevia leaf extract of Malang, Bogor, Tawangmangu respectively, are 14.14%; 22.40%; 66.65%.Key word: Stevia rebaudiana leaf, stevioside content, High Performance Liquid Chromatograph
Jurnal Ilmu Farmasi & Farmasi Klinik Journal of Pharmaceutical Science & Clinical Pharmacy
Authors: Cover Cover
Published: February 2020

Jurnal Ilmu Farmasi & Farmasi Klinik Journal of Pharmaceutical Science & Clinical Pharmacy Pemimpin Umum/ Penanggung jawab Dekan Fakultas Farmasi Universitas Wahid Hasyim Pemimpin Redaksi Ketua Program Studi Farmasi Fakultas Farmasi Universitas Wahid Hasyim Redaktur Ahli Dr. Sumantri, M.S., Apt Prof. Dr. SuwijiyoPramono, Apt Prof. Dr. Mustofa, M.Kes, Apt Dr. Mimiek Murukmihadi, SU., Apt Dr. Mufrod, M.Sc., Apt Redaktur Pelaksana Elya Zulfa, S.Farm., M.Sc., Apt Staf Redaksi : Ririn Lispita Wulandari, S.Farm., M.Si.Med, Apt. Dewi Andini Kunti, S.Farm., M.Farm., Apt Devi Nisa Hidayati, M.Sc., Apt Danang Novianto, S.Farm., Apt Sekretaris Redaksi Anita Dwi Puspitasari, S.Si., M.Pd Distributor Imam Asrofi Alamat Redaksi/Tata Usaha Fakultas Farmasi Universitas Wahid Hasyim Jl. Menoreh Tengah X/22 Sampangan Semarang Telp. 024-8505680, 8505681 Fax. 024-8505680 E-mail :jurnalfarmasiuwh@yahoo.co.id Terbit 2 kali setahun sejak September 2004
METODE ISOLASI YANG MUDAH DALAM ISOLASI SENYAWA β-KAROTEN DARI LABU KUNING (Cucurbita moschata Duch ex Poiret)
Authors: Rollando Rollando , Afthoni Muhammad Hilmi
Published: February 2020

ABSTRACTPumpkin (Cucurbita moschata Duch ex Poiret), a fruit that contains several compounds, has activities to protect the human body from free radicals. Provitamin A is recognized as an antioxidant compound. Antioxidants can protect the body’s damage caused by free radicals. The purpose of this study was to isolate beta carotene compounds and test the purity of beta carotene isolates obtained using DR-UV and infrared spectrophotometry. Pumpkin is extracted using acetone: petroleum ether with a ratio (1: 1). Identification of beta carotene from extracts was carried out using TLC with the mobile phase of ethanol: acetone: n-hexane with a ratio (2: 1: 1) and scan spectrum using a UV-Vis spectrophotometer. Beta carotene was identified as the result of TLC elution on UV 254 and 366 nm which showed 2 spots. Detection of beta carotene spectra was carried out in the range of 350 to 550 nm and obtained beta carotene peaks at wavelength x nm. The extract purification process was carried out using Preparative TLC with the mobile phase of ethanol: acetone: n-hexane with a ratio (2: 1: 1) and obtained isolates cleaned first using chloroform: methanol ratio of 1: 1. The isolates were dried and tested using DR-UV and infrared spectrophotometry. Isolates from Cucurbita moschataDuch ex Poiret extract) contain beta carotene, zeaxanthin.Keywords: pumpkin; beta carotene; isolation
UJI AKTIVITAS PENINGKAT DAYA INGAT FRAKSI ETIL ASETAT EKSTRAK ETANOL BUAH KEMUKUS (Piper cubeba L. f) PADA MENCIT JANTAN GALUR BALB/C DENGAN METODE RADIAL ARM MAZE (RAM)
Authors: Heroweti Junvidya , Anas Yance , Hama Idress Muhammed
Published: February 2020

ABSTRACTNeurodegenerative is often associated with aging. The aging process will affect the decrease in nerve cells, especially brain nerve cells. Ethyl acetate fraction of kemukus fruit ethanol extract (FEAEE) of kemukus fruit has been investigated as a memory enhancer with the Morris water maze (MWM) method. One of the shortcomings of the Morris water maze method is that it causes stress in test animals, thus affecting their memory. This study aims to determine the memory enhancing activity of FEAEE of kemukus fruit with the radial arm maze method This research is an experimental study with pre and posttest matched control group design using 25 male mice, Balb/c strains divided into 5 groups. Mice group 1 as a negative control group were given a 1% CMC Na solution of 17.5 mg/mL. Group mice 2 - 5 were given FEAEE of kemukus fruit with doses of 63, 126, 252, and 504 mg/kgBB, respectively. Test material is given orally for 21 days. Observations were made on the frequency of mice passing the platform correctly and incorrectly and calculating memory scores using the radial arm maze (RAM) method. Differences in memory scores were analyzed by the Mann Whitney test. The results showed that FEAEE steamed fruit has memory enhancing activity. Memory activity was indicated at doses of 63 and 252 mg / kg.Keywords: steamed fruit (Piper cubeba, L. f), ethyl acetate fraction, memory score, radial arm maze
UJI AKTIVITAS ANTIDEPRESAN PERASAN RIMPANG TEMULAWAK (Curcuma xanthorrhiza, Roxb) TERHADAP MENCIT PUTIH JANTAN (Mus musculus)
Authors: Kartikasari Dian , Hairunisa Hairunisa , Natasha Emy Nadya
Published: February 2020

ABSTRACTPrevention and treatment with synthetic antidepressants has many side effects that affect the central nervous system and usage must be under the supervision of a doctor. Whereas prevention and traditional medicine relatively do not cause side effects, are inexpensive, and easy to obtain. One example of traditional medicine from natural ingredients, which can provide an antidepressant effect is ginger rhizome. This research aims to determine whether ginger rhizome have antidepressant effects on male white mice. Antidepressant effect testing was carried out on male white mice (Mus musculus) using the forced swim test method. The part of the plant used is the rhizome of the ginger plant. Curcuma rhizome is made with juice and given orally with a concentration of 20%, 40%, and 60%. The negative control used is Na CMC 0.5%, while the positive control used, namely amitriptilyn. The parameters observed were the duration of immobility time, swimming time and climibing time (in seconds) which were calculated from minutes 3-6 for 6 minutes, and statistical tests were carried out with a confidence level of 95%. The results showed that at a concentration of 40% the curcuma rhizome juice had a significant value (p> 0.05) which means that there was no significant difference in antidepressant effect (%) from the juice of temulawak 56.31% and amitriptylin 78.78%Keywords: ginger rhizome, antidepressants, the forced swim test
UJI DAYA ANTIINFLAMASI EKSTRAK ETANOLIK KULIT TERONG BELANDA (Solanum betaceum, Cav.) PADA MENCIT JANTAN YANG DIINDUKSI KARAGENIN
Authors: Priamsari Margareta Retno , Krismonikawati Rina Ayu
Published: February 2020

ABSTRACT

Inflammation is a normal response to injury due to release of chemical mediators such as

prostaglandins. Solanum betaceum Cav. skin contains flavonoid compounds. This study aims to

determine the antiinflammatory power and the effect of variations in the dose of ethanolic extract

of the skin of Solanum betaceum Cav on Swiss male strain mice caragenin-induced. The ethanolic

extract of Solanum betaceum Cav skin was obtained using remaseration method with 96% ethanol

solvent. Antiinflammatory power test using edema formation method with induction of caragenin

1% intraplantar 30 minutes before administration of the test material. Tests were carried out on 25

mice records which were divided into 5 groups namely negative control (0.5% CMC Na

suspension), positive control (diclofenac sodium suspension in 0.5% CMC Na dose 7 mg/kgBW)

and given suspension respectively. Dutch eggplant skin ethanolic extract in CMC Na 0.5% dose 70

mg/kgBW; 140 mg/kgBW; 280 mg/kgBW orally. The parameters observed were edema thickness

measured using calipers at 30 minute intervals for 360 minutes. The results of edema thickness difference are used to calculate the Area Under Curve (AUC) and the percentage of

antiinflammatory power (% AIP). Dat a were analyzed statistically with the One Way Anova test

and continued by the Post Hoc Test with a 95% confidence level. The results showed that the

ethanolic extract of Solanum betaceum Cav skin contains flavonoid compounds and has

antiinflammatory power. The greater the dose of ethanolic extract of Solanum betaceum Cav skin,

the greater the anti-inflammatory power.
ANALISIS KARAKTERISTIK MUTU SABUN TRANSPARAN BEKATUL BERAS MERAH (Oryza nivara) BERBAHAN DASAR MINYAK GORENG BEKAS
Authors: Susanti Maria Mita , Puspitaningtyas Syela
Published: February 2020

ABSTRACT

The free radicals exposure from daily activities can cause the damage the skin, therefore to avoid

this damage effect can use antioxidants compounds . Brown rice bran is rice milling waste which

has high antioxidant with IC50 is 43,2349 ppm. Efforts to increase the economic value of rice bran

high in antioxidant compounds is by processing rice bran into transparent soap products. This

research was conducted to analyze the quality characteristics of transparent red rice bran soap

(Oryza nivara) based on used cooking oil. The quality characteristics of transparent rice soap

which includes organoleptic soap, pH, foam power, free alkali, and water content. The data were

analyzed descriptively by comparing the results of research with SNI 06-3532 -1994

Based on the results of the study obtained the results of the characteristics of soap that meets the

quality characteristics of SNI 06-3532-1994 soap requirements with a pH of 10,2 , foam power of

2,54 cm, free alkali of 0,034%, and 3,85% moisture content.

Keywords : transparent soap, brown rice bran, used cooking oil, solid soap quality characteristics
PENGARUH WAKTU ULTRASONIKASI TERHADAP KARAKTERISTIK FISIKA NANOPARTIKEL KITOSAN EKSTRAK ETANOL DAUN SUJI (Pleomele angustifolia) DAN UJI STABILITAS FISIKA MENGGUNAKAN METODE CYCLING TEST
Authors: Prihantini Malinda , Zulfa Elya , Prastiwi Listyana Dewi , Yulianti Ikha Dyah
Published: February 2020

ABSTRACT

The nanoparticle system encapsulates and protects flavonoids of suji leaves from photolysis and

oxidation instability. Chitosan is a biocompatible, biodegradable and non-toxic nanoparticles

forming polymer. Ultrasonication is a materials mixing technique under high vibration energy.

The ultrasonication time affects the particle size. The aim of this study was to determine the effect

of the ultrasonication time on physical characteristics of chitosan nanoparticles of suji (Pleomele

angustifolia) leaf ethanol extract and its physical stability after cycling test. Ethanol extract of suji

leaves (EEDS) was obtained by maceration using 70% ethanol. Chitosan EEDS nanoparticles were

made under ionic gelation method using an ultrasonication time of 3 minutes (FI), 6 minutes (FII),

and 9 minutes (FIII). The physical characterization of nanoparticles includes particle size,

polydispersity index, and zeta potential. Chitosan EEDS nanoparticles with the best physical

characteristics (FIII) were tested for stability using cycling test method. The data obtained were

analyzed using the Anova statistical method with a 95% confidence level. The size of EEDS

chitosan nanoparticles (nm) was significantly different in all formulas, FI (374.47), FII (288.43),

and FIII (233.37). The polydispersity index of FI (0.38) and FIII (0.65) were significantly different,

while FII (0.41) was not significantly different. The zeta potential (mV) FI (51.70), FII (46.10), and

FIII (48.60) were not significantly different in all formulas. The physical characteristics of

Formula III after Cycling Test showed a particle size of 455.0 nm, a polydispersity index of 0.174,

and a zeta potential of 20.1 mV.

Keywords: ultrasonication, nanoparticles, chitosan, cycling test, suji leaf (Pleomele angustifolia)
KAJIAN INTERTEKSTUALITAS DALAM NOVEL SITI NURBAYA KARYA MARAH RUSLI DAN LAILA MAJNUN KARYA SYAIKH
Authors: Asteka Pipik
Published: February 2020

Dua karya sastra atau lebih yang mengangkat tema yang sama terdapat persamaan dan perbedaan. Persamaan dan perbedaan tersebut menandakan bahwa setiap pengarang mempunyai pesan tersendiri yang disampaikan melalui karyanya. Persamaan dan perbedaan dalam beberapa karya sastra dapat dianalisis dengan menggunakan prinsip intertekstualitas. Prinsip ini dimaksudkan untuk mengkaji teks yang dianggap memiliki hubungan tertentu dengan teks lain sehingga dimungkinkan suatu karya menjadi hipogram bagi karya sastra selanjutnya. Tujuan penelitian ini adalah pendeskripsian kajian intertekstualitas pada Novel Siti Nurbaya Karya Marah Rusli  dengan Novel LaIla Majnun Karya Syaikh Nizami.

            Penelitian novel “Siti Nurbaya karya Marah Rusli dan Laila Majnun Karya Syaikh Nizami” menggunakan metode kualitatif, yaitu penelitian yang bersifat deskriptif. Penelitian kualitatif merupakan penelitian yang cenderung menggunakan analisis. Pendekatan penelitian ini menggunakan kajian intertekstualitas yaitu membandingkan dua buah teks yang diduga memiliki keterkaitan dan pendekatan intertekstual ini untuk menemukan hipogram dan transformasi dalam novel Siti Nurbaya dan Laila Majnun.

Kedua cerita Novel LaIla Majnun karya Syaikh Nizami dan Novel Siti Nurbaya Cinta karya Marah Rusli di atas yakni memiliki unsur tema yang hampir sama yaitu tentang perjuangan cinta sejati sepasang kekasih yang mengalami cobaan atau hambatan namun menyatu dalam sebuah keabadian mengunakan sudut pandang yang sama yakni sudut pandang orang ketiga dan lain-lain. Selain  persamaan ada juga perbedaan yakni terletak pada struktur gaya bahasa, latar sosial dan lain-lain.

            Novel Siti Nurbaya karya Marah Rusli merupakan hipogram untuk novel Laila Majnun karya Syaikh Nizam. Hal itu terbukti karena adanya persamaan ide dan peristiwa-peristiwa yamg terjadi dalam novel Laila Majnun yang sudah lebih dulu diekspresikan Marah Rusli dalam novelnya yang berjudul Siti Nurbaya, kemudian di transformasikan oleh Syaikh Nizam pada novelnya yang berjudul Laila Majnun.

 

Kata Kunci: Siti Nurbaya, Laila Majnun, Intertekstualitas, Hipogram
KAJIAN STRUKTURAL SEMIOTIK DALAM NOVEL AYAT-AYAT CINTA KARYA HABIBURRAHMAN EL SHIRAZY
Authors: Juidah Imas
Published: February 2020

Penelitian ini bertujuan untuk mendeskripsikan: ikon, indeks dan simbol dalam novel Ayat-Ayat Cinta Karya Habiburrahman El Shirazy. Metode penelitian yang digunakan dalam penelitian ini adalah deskriptif kualitatif. Data dalam penelitian ini adalah kata-kata, kalimat, dan kutipan yang terdapat dalam Ayat-Ayat Cinta. Sedangkan, sumber data dalam penelitian ini adalah novel Ayat-Ayat Cinta Karya Habiburrahman El Shirazy diterbitkan oleh Republika Penerbit dan Pesantren Basmala Indonesia pada tahun 2006 sebanyak 419 lembar. Teknik pengumpulan data pada novel yang digunakan dalam penelitian ini adalah teknik baca dan catat.  Berdasarkan hasil penelitian yang telah dilakukan mengenai kajian strukturalisme semiotik dalam novel Ayat-Ayat Cinta karya Habiburrahman El Shirazy dapat disimpulkan bahwa melalui kajian strukturalisme semiotik terdapat tiga ikon, yaitu ikon universitas Al-Azhar sebagai penanda lembaga pendidikan, ikon tempat, dan ikon ibadah sebagai penanda agama atau kepercayaan. Terdapat tiga indeks, yaitu indeks aktivitas atau pekerjaan yang dilakukan tokoh-tokoh dalam novel, indeks penampilan fisik seseorang, dan indeks perilaku tokoh. Terdapat lima simbol, yaitu simbol nama, simbol pengorbanan, simbol persahabatan, simbol cinta kasih, dan simbol kesederhanaan.

 

Kata Kunci: Semiotik, Ikon, Indeks, Simbol, Novel