bluuebunny/crossref_metadata_2025 huggingface dataset:
Endophytic fungal diversity in Terminalia arjuna (Roxb.) Wight & Arn. of Tripura, Northeast India at different sampling sites and plant organs
Authors: Tripura Samrat , Debbarma Prasenjit , Paul Suman , Saha Rahul , Ajay Krishna Saha
Published: June 2024

Endophytic fungi are ubiquitous in plant kingdom and play a vital role in balancing the microenvironments within the host plants. Fungal endophytes isolated from ethno-botanically important plants were the source of several secondary metabolites with potential biological activities. The present study has documented the variability of culturable endophytic fungi from Terminalia arjuna (Roxb.) Wight & Arn. (Combretaceae), a widely used medicinal plant of Tripura, North-east, India. A total of 613 fungal strains were isolated from 720 tissue segments viz. leaves, bark and root of T. arjuna. The highest numbers of endophytic fungal isolates were found to be colonizing in leaves (257) followed by barks (182) and the least number of isolates were obtained from roots (174). The fungal isolates were classified into 27 individual fungal strains based on morphological and microscopic features. A total of 9 endophytic fungal strains were identified using the nuclear ribosomal DNA internal transcribe sequence and were subjected to phylogeny analysis. Most of the identified morphotypes belonged to phylum Ascomycota. Among all the isolates, Diaporthe sp., Fusarium sp., Colletotrichum sp., Penicillium sp. were the most abundant fungal isolates from T. arjuna. The fungal orders namely Sordariomycetes was the most prevalent followed by Eurotiomycetes and Dothideomycetes. Colonization rate, isolation rate, colonization frequency and relative frequency results suggest that leaf segments harbors maximum endophytic fungi assemblage compared to bark and root tissues. The analysis of Shannon (H'), Simpson (1-D), Fisher alpha (a) and Brillouin (HB) indices had significant difference with locations and tissue type. The host plant harbor unique endophytic community composition in studied sampling locations and their colonization varied between the inoculated vegetative parts of the plant. As no such study has been undertaken in the North- eastern part of India, this pioneer study may enable to unearth novel fungal endophytes that might have beneficial role in plant growth promotion, stress tolerance etc.
Capabilities and drawbacks of mass spectrometry in the forensic field: analysis of real cases dealing with toxicology and explosives
Authors: Furlan Giada , Canò Emanuela , Zuddas Matteo , Giuliano Antonio
Published: June 2024

Ever since its invention, mass spectrometry has been seen as a remedy for all of the riddle that an analytical chemist was ever called to answer. Indeed, a good mass expert, provided with a good instrument and an updated library, would be able to answer to the question “what is it?” or “what does it have inside?”. In most of the cases, nevertheless, there is sometimes the need of using other type of techniques in order to avoid misunderstandings and wrong interpretations of the results. Therefore, the aim of this work is to compare real forensic cases where mass spectrometry played a fundamental role to obtain tangible and trustable answers, to other ones where this technique proved to be totally misleading. Those that will be shown, are real, concrete cases – slightly modified in order to make them unrecognisable.
Acutely ill patients suffering ARDS with massive, generalized oedema: Are they in a state of hypo- or hypervolemia?
Authors: Ghanem Ahmed N. M.
Published: June 2024

I read with great interest this recently published article by Professors Dull, R.O. and Hahn, R.G.1 The authors are commended on this review based on evidence from published reports that represent the current understanding of the condition and its scientific basis. The authors have faithfully and factually summarized the evidence based on published reports, including some of the commonly received errors and misconceptions on the scientific foundation2 that identifying and correcting may help answer the vitally important question in the report's title. I asked myself the very same question “What is wrong?” after attending the post-mortem examination of 3 patients who were killed by ARDS, complicating the TUR syndrome back in 1981. It took me >40years of hard, comprehensive, intensive, and profound scientific research to find the correct answer. The authors acknowledge that Starling’s law represents the scientific foundation of the volume-pressure relationship of the vascular, capillary, and interstitial fluid compartments. It thus underlies and dictates the rules that govern fluid therapy in shock management. This is the subject on which both authors are among the top world authority. My research has demonstrated clearly and completely the substantial evidence that Starling’s law is wrong, and the correct replacement is the hydrodynamics of the porous orifice (G) tube3 that has been gathered in a book.4 This will revolutionize our understanding of the condition and related issues, particularly on the path-etiology and management of ARDS. The hydrodynamics of the G tube in a surrounding chamber mimics the capillary-interstitial fluid (ISF) transfer (Figure 1).
Improving Patient Portal Activation for Newborns in the Well Baby Nursery
Authors: Sriraman Sheetal , Saadoon Reem , Bochner Risa , Khandakar Saema
Published: June 2024

BACKGROUND

Patient portals provide parents access to their child’s health information and direct communication with providers. Our study aimed to improve portal activation rates of newborns during nursery hospitalization to >70% over 6 months. Secondarily, we describe the facilitators and barriers to portal use.

METHODS

The study design used a mixed-methodology framework of quality improvement (QI) and cross-sectional analyses. The Model for Improvement guided QI efforts. The primary outcome was the proportion of portals activated for newborns during nursery hospitalization. Interventions included portal activation algorithm, staff huddles, and documentation templates. Telephone interviews were conducted with a randomized sample of mothers of infants who activated the portal. These mothers were divided into portal “users” and “nonusers.” We examined sociodemographic variables and health care utilization outcomes in the 2 groups.

RESULTS

Portal activation increased from 12.9% to 85.4% after interventions. Among 482 mothers with active portals, 127 (26.3%) were interviewed. Of those, 70% (89 of 127) reported using the portal, and 85.4% (76 of 89) found it useful. Reasons for accessing the portal included checking appointments and reviewing test results. Lack of knowledge of portal functionality was the main barrier to portal use (42.1%). Portal users were less likely to have a no-show to primary care appointments compared with nonusers (44.9% versus 78.9%, P < .001).

CONCLUSIONS

Portal activation rates increased after QI interventions in the nursery. Most parents accessed the portal and found it useful. Portals can improve health care delivery and patient engagement in the newborn period.
Forming the Ability of Younger Students to Behave Safely on the Internet
Authors: Shyshak Andriana , Chaika Volodymyr , Shcherbiak Iurii , Gažiová Maria , Tvrdon Miroslav
Published: June 2024

Aim. The aim of the research is to elucidate the essence of the concept of "safe behaviour on the Internet"; and determine the means of developing digital literacy skills among primary school students, as well as the specifics of their usage. The study also involves experimentally investigating the effectiveness of the identified tools in enhancing the level of safe behaviour on the Internet skills among primary education learners.
Methods. The research used the following methods: analysis, generalisation, experiment, observation, and statistical methods.
Results. The use of thematic stories and comics, ready-made didactic games and exercises, conducting thematic lessons according to plans, etc., provided that the activity is systematic and consistent, taking into account the age and individual characteristics of students in grades 1-4, contributes to the successful development of the ability of primary education learners to behave safely on the Internet.
Conclusion. The ability to behave safely on the Internet is the ability to perform online activities without harming one's own health, the health of others and financial situation, formed on the basis of knowledge and experience. The means of forming the skills of safe behaviour of primary school students on the Internet are thematic fairy tales, stories, presentations, video clips, illustrative material, comics, ready-made materials for didactic games and exercises, development of thematic lessons, computer, etc. The results of the experiment allowed us to draw conclusions that by using the developed tools in the learning process, it is possible to increase the level of primary school students' ability to behave safely on the Internet.
Student Evaluation in the Subject of Technology in Primary Schools in Slovakia
Authors: Lukáčová Danka , Botló Patrik
Published: June 2024

Aim. School evaluation is a sensitive process that involves teachers, students, and their parents in various ways. This article focuses on researching student evaluation by teachers in the subject of Technology in Slovak primary schools. The research aims to determine how teachers assess students in the subject of Technology.
Methods. As a research tool, we used a self-designed questionnaire for teachers. We analysed the respondents' answers using descriptive statistical methods. To ascertain differences in responses between qualified and unqualified teachers, we employed the chi-square test.
Results. By analysing the data obtained from 107 questionnaires, we found that technology teachers mostly employ an individual approach when evaluating students and emphasise the practical aspects of the subject. Among the evaluation methods, grading scales for summative student assessment prevail. At the same time, there were statistically significant differences between qualified and unqualified teachers. We also observed statistically significant differences in evaluations between qualified and unqualified teachers.
Conclusion. For this reason, it is necessary to ensure an increase in the number of qualified and internally motivated technology teachers in primary schools, as only such teachers can motivate and inspire their students to pursue this field of study.
Harmonizing Traditional and Modern Maternal Healthcare Practices in Cirebon, Indonesia
Authors: Busro Busro , Hilmi Fuad , Qodim Husnul
Published: June 2024

Aim. This research aims to explore the integration of Traditional Knowledge and Traditional Practices during pregnancy and childbirth with Modern Health Knowledge and Practices in Cirebon, Indonesia,
Methods. This research uses a qualitative method that includes participatory observation and interviews. Participants in this study consisted of pregnant mothers or patients giving birth in village health centres in Cirebon. Data was collected through participatory observations during visits to health centres and in-depth interviews with the participants.
Results. The research results indicate that this integration occurs naturally in Cirebon. Respondents combine traditional and modern healthcare practices to meet their health needs during pregnancy and childbirth, taking into consideration cultural factors, religion, family support, healthcare accessibility, and past experiences.
Conclusion. This study demonstrates that the integration of Traditional Knowledge and Traditional Practices during pregnancy and childbirth with Modern Health Knowledge and Practices is crucial in maternal healthcare practices in Cirebon, Indonesia.
Cognitive value. The findings of this study can assist healthcare practitioners in improving the quality of maternal healthcare services in Indonesia and can serve as a reference for future research.
Die Vögel Österreichs: Kommentierte und illustrierte Liste der Arten und Unterarten
Authors: Khil Leander , Ranner Andreas , Berg Hans-Martin , Dvorak Michael
Published: June 2024

This list comprises the 447 bird species and their subspecies that have been recorded in the wild in Austria up to and including 2023. Species names and key are given in English. It shows in which federal states the different taxa have been recorded and in which they were breeding in the years 2013–2023. A short annotation describes distribution patterns within the country and phenological peculiarities, status and category are listed and the seasonal presence is depicted. For regular breeding species the current status on the national Red List and the national breeding population are given. For species that have not been recorded more than ten times, each record is listed. 444 taxa are illustrated by photos from Austria.
Cotognoaceto
Authors: Iddison Philip
Published: June 2024

The author recounts the results of his recreation of two chutneys that he made by backtracking from the data divulged on a commercial product label and attempt to re-create a similar product.
Book Reviews
Authors: Field Michele
Published: June 2024

Is Food The New Sex? Mary Eberstadt Hoover Institution Policy Review | no. 153 | Feb-Mar 2009 | also: www.hoover.org:80/publications/policyreview/38245724
Globesity. A Planet Out of Control? Francis Delpeuch et al Earthspan | 2009 | 180pp| £17.99
The Vital Ingredient Royal Society of Chemistry | 2009 | 88pp | www.rsc.org
Fighting the Banana Wars and Other Fairtrade Battles Harriet Lamb Rider | 2008 | 246pp | £8.99
The Dining Nobility. From the Burgundian Dukes to the Belgian Royalty P. Janssens and S. Zeischka, eds Brussels University Press | 2008 | 266pp. | 39.95 euros
Bite Me. Food in Popular Culture Fabio Parasecoli Berg | 2008 | 168p | £55.00/£16.99
Eating India Chitrita Banerji Bloomsbury | 2008 | 266p | £8.99
Eat Love Marije Vogelzang BIS Publishers Amsterdam | 2008 | 160pp | £32.50
Let Them Eat Junk Robert Albritton Pluto Press | 2009 | 259p | £17.99
The Spaghetti Tree Alasdair Scott Sutherland Primavera | 2009 | 255p | £14.99
Sushi and Beyond: What the Japanese Know about Cooking Michael Booth Cape | 2009 | 329pp | £12.99
Feeding the Whole World Louise Fresco TED broadcast http://www.ted.com
‘Go Ahead. Spoil My Appetite’ Geoff Nicolson NY Times Sunday Book Review | 3 May 2009 | p.23 | also online
Agriculture in Urban Planning Edited by Mark Redwood Earthscan | 2009 | 248pp | £65
Why the Chinese Don’t Count Calories Lorraine Clissold Constable | 2008 | 223pp | £8.99
The Wild Life: A Year of Living on Wild Food John Lewis-Stempel Doubleday | 2009 | 293pp | £16.99
Food: The Key Concepts Warren Belasco Berg | 2008 | 158pp | £14.99
Waste: Uncovering the Global Food Scandal Tristram Stuart Penguin | 2009 | 451pp | £9.99
Street Food www.youtube.com 2008-2009 | free
Bad Science Ben Goldacre Harpers | 2008 | 370pp | £8.99
Shoot the Cook David Pritchard Fourth Estate | 2009 | 266pp | £16.99
TvTropes www.tvtropes.org
Scientific and Gastronomic Lexicon Harold McGee, introduction Alicia Foundation, Alicante | 2009 | www.worldsofflavorspain.com/food-and-technology
‘Spider Plant’ at Try African Food www.try-african-food.com
Synthesis, Characterization and Biological Activity Evaluation of Novel Quinoline Derivatives as Antibacterial Drug
Authors: Kassar Maryam Jamaal , Ezzat Mohammed Oday
Published: June 2024

Quinoline and its derivatives are a family with unique medicinal properties, including antibacterial effects. It was assumed that the four quinoline derivatives 1, 2, 3 and 4 had significant activity against pathogenic bacteria. These compounds were synthesized and characterized by TLC, IR, 1H NMR, and 13C NMR analyses. The biological activity of compounds was determined as inhibition zone (IZ) in mm. For compound 1 IZ was 19 ± 0.22 against Klebsiella pneumoniae, IZ was 18 ± 0.22 against Bacillus subtilis, and IZ was 17 ± 0.22 against Staphylococcus aureus. 2 displayed IZ of 18 ± 0.22 against both Klebsiella pneumoniae and Bacillus subtilis. 3 showed IZ of 17 ± 0.22 against Staphylococcus aureus. 4 displayed IZ of 21 ± 0.22, thus showing a higher inhibitory activity against Escherichia coli, than ciprofloxacin. These results demonstrate the potential of the synthesized compounds to work as antibacterial drugs against these strains by inhibiting or deactivating the target proteins.
QSRR Modeling of Lipophilicity of New Spirohydantoin Derivatives Determined with Various TLC Systems
Authors: Tot Kristina A. , Lazić Anita M. , Djaković Sekulić Tatjana Lj.
Published: June 2024

A Quantitative structure-retention relationship (QSRR) analysis has been performed on the chromatography parameters of lipophilicity of selected spirohydantoins. Multiple linear regression (MLR) was applied to construct the QSRR models. The chromatographic parameters of lipophilicity were determined by reversed-phase thin-layer chromatography. Chromatographic analyses were performed on C-18 modified silica gel with a two-component mobile phase consisting of water and protic organic solvent (ethanol, n-propanol, i-propanol, or t-butanol) in different ratios. QSRR models were also created for additional four aqueous mobile phases: acetone-water, acetonitrile-water, tetrahydrofuran-water, and 1,4-dioxane-water (results published before). In total, chromatographic lipophilicity parameters obtained for two types of organic solvents were subject of the QSRR. The predictive ability of each model was evaluated using internal and external validation. The best QSRR model for predicting the chromatographic parameter of lipophilicity was obtained for tetrahydrofuran as an organic solvent.
theses, Crystal Structures and Antimicrobial Activity of Copper(II) Complexes with the Ligand N,N’-Bis(4-bromosalicylidene)propane-1,2-diamine
Authors: Hao Yu-Mei , Sun Chang-Chun
Published: June 2024

Three new copper(II) complexes, [CuClL] (1), [CuBrL]n (2) and [CuL(NCS)]n (3), derived from the Schiff base 2,4-dichloro-6-((2-pyrrolidin-1-ylethylimino)methyl)phenol (HL) have been prepared and characterized by spectroscopic methods, as well as single crystal X-ray determination. The Cu atom in complex 1 is in square planar coordination, and those in complexes 2 and 3 are in square pyramidal coordination. The Schiff base ligand coordinates to the Cu atoms through phenolate oxygen, imino nitrogen and pyrrolidine nitrogen. The antibacterial activities of the Schiff base and the three copper complexes have been assayed on the bacteria Staphylococcus aureus and Escherichia coli and the yeast Candida parapsilosis.
In Silico Exploration of Molecular Mechanisms for Inhibiting Inflammatory Responses by 3Н-Thiazolo[4,5-b]pyridin-2-one Derivatives
Authors: Klenina Olena
Published: June 2024

Combined in silico strategy for molecular mechanisms exploration of a series 3H-thiazolo[4,5-b]pyridin-2-ones exhibiting strong anti-exudative action through QSAR analysis, molecular docking and pharmacophore modelling is reported. GA-ML technique was used for QSAR models generation with 2D autocorrelation descriptors. One- and two-parameter regressions revealed that certain structural patterns or heteroatoms contribute mutually to the anti-exudative activity potentiation. Possible action mechanisms were discovered through flexible docking simulations with cyclooxygenase pathway enzymes (COX-1, COX-2, mPGES-1). Docking results indicated the possibility of stable complexes formation with the effective docking scores and proper orientation of ligands within the enzymes active sites. Pharmacophore modelling was carried out using protein-ligand interaction fingerprints methodology. Two- and three-centre 3D pharmacophore queries were constructed. Their analysis indicated the functionality of bicyclic thiazolopyridine scaffold proved by the steric placement of heteroatoms in the corresponding pharmacophore centres.
Pengaruh Latihan Kekuatan Otot Lengan dan Drilling Terhadap Peningkatan Ketepatan Pukulan Overhead Lob
Authors: Bahari Dewa Adi , Widiyatmoko Fajar Ari , Fahmi Donny Anhar
Published: June 2024

This research was motivated by problems including the lack of arm muscle strength, arm muscle explosive power and overhead lob punches possessed by athletes aged 9-17 years in PB. Walet Pati city. The aim of the research was to determine how much influence push-up and lob drilling exercises had on increasing the accuracy of overhead lob punches in athtletes PB. Walet Pati city. Type of quantitative research with experimental methods. The research design in one group pretest-posttest design to find out the comparison tesults of the pretest and posttest after the researcher has carried out treatment for 12 meetings. Population of 20 athletes, purposive sampling. Results highest pretest with interval (36 X ≤ 53) has a frequency of 15 athletes, namely 75%. Highest posttest results with intervals (54 X ≤70) in the category (good eneugh) the frequency of 6 athletes is 30%. The lowest posttest results were in the (fair) score interval category (36 X ≤ 53) with a frequency of 14 athletes, namely 70%. Pretest score ≤posttest results. This means that there is an increase in push-up and drilling lob training on the accuracy of the overhead lob strokes of PB. Walet Pati city athletes. The results of the paired samples t-test using the SPSS application swow that the accurary of the overhead lob hit is at a significant level, namely Sig.(2-tailed) with a value of .000 meaning ≤ 0.05 so Ho is rejected and Ha is accepted. If Ha is accepted, it means that there is a significant influence from push-up and drilling lob training on increasing the accuracy of overhead lob strokes in athletes aged 8-17 years PB. Walet Pati city.
PROBLEMS OF IMPROVING THE FEDERAL STRUCTURE OF RUSSIA
Authors: Бевзюк П.И. , Бевзюк С.А.
Published: June 2024

Исследование проблемных аспектов нормативно-правового регулирования федеративного устройства страны является крайне актуальным, поскольку форма государственного правления в России по историческим меркам имеет сравнительно небольшой срок, чтобы успеть окончательно выработать правильную модель правового регулирования организации публичной власти в субъектах федерации и их взаимоотношений с федеральным центром. Необходимостью постоянно совершенствовать федеративную систему государства объясняется живой непрекращающийся интерес отечественных правоведов к этой теме. На основе использования общенаучных методов исследования, таких как анализ и синтез, дедукция и индукция, метод классификаций, были выявлены исторические предпосылки формирования федеративного устройства в  России, рассмотрены современные проблемы ныне существующей формы государственного правления. При работе с  нормативно-правовыми актами использовался формально-юридический метод, а  благодаря сравнительно-правовому методу удалось сопоставить российское законодательство и законодательство зарубежных стран. В исследовании применялось сочетание различных методов, что позволило рассмотреть проблемы, связанные с двумя аспектами федеративного устройства России – территориальным и национальным, и сформулировать предложения по их решению посредством совершенствования законодательства.

Studying the problematic aspects of the legal regulation of the country’s federal structure is extremely relevant, because, by historical standards, the form of government in Russia, has a relatively short period of time to finally develop the correct model of legal regulation of the organization of public power in the constituent entities of the federation and their relationship with the federal center. The need to constantly improve the federal system of the state explains the ongoing interest of domestic legal scholars in this topic. Using the general scientific research methods such as analysis and synthesis, deduction and induction, and the classification method, the historical prerequisites for the formation of a federal structure in Russia are identified, and the modern problems of the current form of government are considered. The formal-legal method was used in working with normative-legal acts, and due to the comparative-legal method it was possible to compare the Russian legislation and the legislation of foreign countries. The study used a combination of methods to address the problems associated with two aspects of the federal structure of Russia – territorial and national. The proposals were formulated for solving them by improving the legislation.
SOCIO-LEGAL ASPECTS OF THE ALLOCATION OF SPECIAL TYPES OF FRAUD TO A SEPARATE CRIME
Authors: Свешников А.В.
Published: June 2024

На современном этапе развития российского уголовного права выделение специальных видов мошенничества в отдельный состав преступления обусловлено негативной динамикой преступлений, относящихся к  мошенничеству, глобальными происшествиями, трансформирующими социальную сферу, цифровизацией социально-экономической среды и возникновением новых видов мошенничества, усложнением схем мошенничества на фоне развития социально-экономических институтов, наличием этических дилемм в законодательной и правоприменительной практике уголовной сферы. В статье рассмотрены социально-правовые аспекты, позволяющие выделить специальные виды мошенничества в отдельный состав преступления.

At the present stage of development of Russian criminal law, the separation of special types of fraud into a separate crime is due to the negative dynamics of crimes related to fraud; global events transforming the social sphere; digitalization of the socio-economic environment and the emergence of new types of fraud; the complication of fraud schemes against the backdrop of the development of socio-economic institutions; the presence of ethical dilemmas in legislative and law enforcement practice in the criminal sphere.
Brazil's interests in the Arctic
Authors: Viakhireva Natalia
Published: June 2024

The Arctic region attracts increasing attention from a wide range of countries. Among the non-regional players seeking to enter the Arctic is Brazil. For Brazil, participation in the development of the Arctic region is a way to increase its role both within the BRICS and in the international arena. The country sees its participation in Arctic projects both in the multilateral BRICS format within the framework of the Working Group on Ocean and Polar Research, and as an independent participant, based on the experience of Antarctic research within the PROANTAR program. In the new political and economic conditions Russia is aimed at building a multi-vector policy in the Arctic region. The country is building cooperation with new "players" in the Arctic, mainly with the BRICS member countries. Experts consider Brazil as one of Russia's potential partners in the Arctic in the following areas: environmental protection and combating climate change; water management; sustainable agriculture; support for indigenous peoples; and energy projects.
RELATIONSHIP BETWEEN BODY MASS INDEX AND ACTIVITIES OF DAILY LIVING ELDERLY IN RURAL COMMUNITIES
Authors: Susanto Joko , Rukanah Rukanah , Iswatun Iswatun
Published: June 2024

Introduction: A high Body Mass Index (BMI) is known to be associated with mortality and morbidity in the elderly. However, other studies also show the opposite results regarding high BMI as a protector against Activity Daily Living (ADL). Accurate quantification of the role of BMI in the incidence of disability in ADL. Given the increasing prevalence of overweight and obese individuals and the long life spans in the population. This study aims to determine the relationship between Body Mass Index and Daily Life Activities in population-based elderly people. Methods: The method used in this research is a cross-sectional observational study conducted on 167 respondents from rural areas in the Lamongan Regency, using a consecutive sampling approach. BMI scores and the Barthel Index were recorded among respondents. Data were analyzed using the Spearman Test with a significance level of p<0.05. Results: A total of 167 respondents came from rural areas in Lamongan Regency, dominated by 96 (57.5%) women and 71 (42.5%) men. The Spearman Test results found a weak and significant positive correlation between body weight and daily activities (r= 0.167; p<0.05). Apart from that, a significant weak positive correlation was also found between BMI and ADL (r= 0.157; p<0.05). Conclusions: The results of the study show that increasing the BMI value has a protective effect on ADL, so it can be concluded that higher body weight and BMI are associated with increasing Barthel ADL scores.
WIKIPEDIA as a Platform for the Implementation of Current Tasks for the Strategic Development of Academic Libraries of Ukraine in the Information Age
Authors: Mamon Viacheslav , Loboiko Olena
Published: June 2024

The report highlights the internet project of the library of the Kharkiv State Academy of Culture "KhSAC in Wikipedia" as the implementation of the strategy for the modern development of libraries of higher education institutions. The main stages of the project implementation and functioning on the pages of the world's largest encyclopedia aimed at increasing youth interest in higher information-library, culturological, and artistic education, as well as popularizing the achievements of KhSAC, are shown. The methodological support of the Kharkiv Korolenko State Scientific Library in implementing the project is also highlighted.
Development Strategy of the KKSSL: Destructive Factors of Influence, Adaptation to War and Ways of Post-War Reconstruction
Authors: Petrenko Natalia , Viriutina Kateryna
Published: June 2024

The report analyses the development strategy of the KKSSL for 2022–2026 in the context of the destructive effects caused by the armed aggression of the Russian Federation against Ukraine. The steps of adaptation to military realities are described in detail: development of remote services, and attraction of international support. Perspective ways of development and post-war reconstruction of library activities are identified.
An Explainable AI-based Machine Learning Approach for Predicting Diabetes in the Early Stage Using the Influential Features
Authors: Das Utsha , Ahmed Boshir
Published: June 2024

One of the most prevalent illnesses, diabetes does not directly result in patient mortality. But, it increases the risk of death. Any disease that may be predicted in its early stages can lessen its fatal effects while also enhancing the quality of the healthcare system. For the early-stage prediction of diabetes or such types of non-communicable diseases, we need the proper set of influential features. This research has developed a machine learning-based disease prediction model to identify the influential features for diabetes prediction and give a near-perfect classification accuracy. This model includes Min-Max normalization for data normalization, Isolation Forest (iForest) for outlier removal, Synthetic Minority Oversampling Technique (SMOTE) for oversampling, Random Forest based Recursive Feature Elimination (RFE-RF) test, Chi-Square test, and Minimum Redundancy Maximum Relevancy (mRMR) test based feature selection methods for identifying the influential features, and Support Vector Machine (SVM), K Nearest Neighbor (KNN), and Naive Bayes (NB) for the classification. The results clarify that the proposed model outperforms the previous models and studies. The SVM has attained an accuracy of 99.58% in classification using the five features chosen from the Chi-Square test. Lastly, SHAP, an explainable AI model, has been used to assess the classifier model’s performance. These selected features and the classifier model can be used for early-stage diabetes prediction.
Predicting Mortality from Fungemia in Pediatric Intensive Care: A New Model Using Candida Score and Key Risk Factors
Authors: Al-Sofyani Khouloud Abdulrahman , Uddin Mohammed Shahab
Published: June 2024

Introduction: The escalating morbidity, mortality, and healthcare costs associated with invasive candidiasis pose significant challenges in pediatric intensive care units (PICUs). Conventional diagnostic methods fall short in effectiveness, while various risk factors exacerbate the prevalence of these infections. This study introduces a novel model that amalgamates the Candida Score with key predictors to enhance the specificity and applicability of mortality risk assessments for pediatric patients with fungemia.
Methods: This retrospective cohort study aimed to develop an integrated model for estimating mortality risk in children with fungemia in PICUs. We constructed and evaluated multiple predictive models using the Candida Score and other relevant clinical and laboratory variables. The discriminative abilities of the models were assessed using the area under the receiver operating characteristic curve (AUC).
Results: The study cohort comprised 85 pediatric patients admitted between 2016 and 2020, with a median age of 6 months and a male predominance of 62.4%. The mortality rate was 45.9%. Candida albicans was the most prevalent causative agent, accounting for 37.55% of fungemia cases. Multivariable Logistic regression revealed the duration of mechanical ventilation, and the Candida Score were significant predictors of mortality. Each additional day of ventilation increased mortality odds by 11.5% (OR = 1.115, 95% CI: 1.025-1.212, p = 0.011), while a higher Candida Score more than doubled the odds (OR = 2.205, 95% CI: 1.359-3.578, p = 0.001).The Random Forest predictive model demonstrated superior discriminative performance, with an AUC of 0.838 (95% CI: 0.738-0.917), outperforming Gradient Boosting and Logistic Regression models, which had AUCs of 0.7759 (95% CI: 0.667-0.877) and 0.7085 (95% CI: 0.589-0.813), respectively. Although the internal validation yielded satisfactory results, external validation is warranted.
Conclusion: This study presents an innovative approach for accurately assessing the risk of mortality due to fungemia in PICU patients by integrating the Candida Score with critical predictors. The Random Forest model emerged as the most effective predictive tool due to its exceptional discriminative ability.
Does tDCS Selectively Modulate the Pre-frontal Cortex Hemodynamics? An Immediate Effect-Controlled Trial on Depressed and Healthy People
Authors: Campos Laura Oliveria , Souza Macedo Maria de Cássia Gomes , Vespasiano Monerat Vheyda Katheleen , do Rosário Ferreira Kariny Realino , Cunha dos Santos Mayra Evelise , Esquirio Arthur Ferreira , Guimarães Alves Ana Luiza , Gama Gabriela Lopes , Barbosa Alexandre Carvalho
Published: June 2024

Despite the recommendation to treat depression using the transcranial direct current stimulation (tDCS), novel findings raised doubts over the tDCS efficacy in managing depressive episodes. Neurophysiologic approaches to understand the specificities of brain responses to tDCS in de-pressed patients remains a feature. Objective: to compare the immediate hemodynamic responses to tDCS on left dorsolateral pre-frontal cortex (DLPFC; F3-Fp2 montage) in patients with depres-sive disorder and healthy controls (no additional stimuli). Methods: Sixteen participants were al-located in depression group and 16 in the control group. Both groups received 2mA tDCS for 20 minutes, using the F3-Fp2 montage. The hemodynamic effect over the DLPFC was assessed using near-infrared intracranial spectroscopy (NIRS) positioned on the left supraorbital region (Fp1). Mean, minimal and maximal values of baseline and post-stimulation rates of oxygen saturation (SatO2) were recorded. The oxygenated hemoglobin rates (HbO) were extracted. Results: Be-tween-group differences were detected for mean and minimal baseline rates of SatO2 and HbO levels. The depression group showed lower results compared to the control group. After the pro-tocol, only the depression group showed increased mean and minimal rates of SatO2 and HbO. The post-tDCS rates were equal for both groups. Conclusion: The findings showed immediate anodal tDCS effects over DLPFC hemodynamics. The effects were exclusive for the lowest base-line rates group, not affecting the normal oxygen rates group. The minimal increase of SatO2 and HbO rates after the protocol in the depression group suggests that those with reduced cerebral perfusion may be more affected by tDCS.
The Comparison of Routing Algorithm for SDN Network using AI for Future Network
Authors: Ahmed Afshaar , Siddiqui Fahad Ahmed , Rizvi Huma Hasan , Rizvi Jeffri Ali , Khan Abdul Moid , Ahmed Manzar
Published: June 2024

After the invention of new IoT devices the new connection has been added in the network and bulk of data   flow in the system. AI is very famous algorithum and software-defined networking (SDN) is new fast network controlling method both can be integrate for fast and secure network-related scenarios and finding great experience and growing interest in the research community. The present network connected to many number of objects over the Internet and present a complex scenario. To ensure security, privacy, confidentiality, and programmability, the architecture of AI and blockchain for SDN network is proposed in this paper. For network service provider this is ample time to apply artificial intelligence (AI) and blockchain (BC) in a software-defined network controller to ensure a secure network control, traffic management and system optimimum performnce. Also for shortest path to reduce delay in the network, the best routing algorithum must be apply in the network.  The AI (artificial intelligence) algorithum can help SDN controller to fastdecision to reduced delay and can provide security in the network.  In this paper routing algorithm also will be investigate  faster Network.
Levitation and controlled MHz rotation of a nanofabricated rod by a high-NA metalens
Authors: Sun Chuang , Pi Hailong , Kiang Kian Shen , Georgescu Tiberius , Ou Jun-Yu , Ulbricht Hendrik , Yan Jize
Published: June 2024

An optically levitated nanoparticle in a vacuum provides an ideal platform for ultra-precision measurements and fundamental physics studies because of the exceptionally high-quality factor and rich motional modes, which can be engineered by manipulating the optical field and the geometry of the nanoparticle. Nanofabrication technology with the ability to create arbitrary nanostructure arrays offers a precise way of engineering the optical field and the geometry of the nanoparticle. Here, for the first time, we optically levitate and rotate a nanofabricated nanorod via a nanofabricated a-Si metalens which strongly focuses a 1550nm laser beam with a numerical aperture of 0.91. By manipulating the laser beam’s polarization, the levitated nanorod’s translation frequencies can be tuned, and the spin rotation mode can be switched on and off. Then, we demonstrated that the rotational frequency relies on the laser beam’s intensity and polarization as well as the air pressure. Finally, a MHz spin rotation frequency of the nanorod is achieved in the experiment. This is the first demonstration of controlled optical spin in a metalens-based compact optical levitation system. Our research holds promise for realizing scalable on-chip integrated optical levitation systems.
Blood Vessels Disease Detection of Coronary Angiography Images using Deep learning Model
Authors: Osama Mohd , Kumar Rajesh , Shahid Mohammad
Published: June 2024

Presently Coronary artery disease, often caused by the narrowing of the coronary artery lumen due to atherosclerosis, is a leading cause of death. Coronary angiography also known as cardiac catheterization or X-ray angiography, is a medical procedure that uses X-ray imaging to visualize the coronary arteries, which supply blood to the heart muscle. X-ray angiography is procedure to assess the blood flow through these arteries and to identify any blockages or abnormalities. The accuracy of X-ray angiography depends on the quality of the imaging equipment as well as experience and expertise of the radiologist. Poor image quality could affect the accurate diagnosis of coronary arteries. Manual interpretation of angiography images is subjective and time consuming. In some cases, small or diffuse blockages may not be easily visible, and additional imaging techniques may be required. Therefore, early automated detection of blockage of heart vessels became necessary for detection and diagnosis. The artificial intelligence algorithms could play a vital role in this area. In this paper, a deep-learning based algorithm has been used for recognition of blockage in coronary angiographic visuals. Here, we proposed deep learning (YOLOv8) models for the detection of blockage into blood vessels coronary angiography images. In this experiment about 1934 labelled X-ray angiography images has been used from Mendeley. For Experimentation purpose, images are preprocessed and augmented. Total 80% images have been used for training and 20% images has been used for testing. The experimental results show that the measuring metrices of proposed model for detection of blood vessels blockage area in rectangular box. The performance of model represented by predicted value of Precision, recall, mean average precision (mAP) and F1 score are, 99.4%, 100%, 99.5% and 99.7% respectively.
Assessment of past dioxin emissions from waste incineration plants based on archive studies and process modeling: a new methodological tool
Authors: Zhang Xiaocheng , de Aragao Alexis , Moll-François Fabien , Berthet Aurélie , Breider Florian
Published: June 2024

Pollution from past industrial activities can remain unnoticed for years or even decades because the pollutant has only recently gained attention or identified by measurements. Modeling the emission history of pollution is essential for estimating population exposure and apportioning potential liability among stakeholders. This paper proposes a novel approach for reconstructing the history of polychlorinated dibenzo-p-dioxin (PCDD) and polychlorinated dibenzofuran (PCDF) pollution from municipal solid waste incinerators (MSWIs) with unknown past emissions. The proposed methodology relies on the search for technical and operational data on the pollution source in archives, the extraction of representative data from the scientific literature, and the use of kinetic models of the formation and decomposition of PCDD/Fs within combustion chambers. This new methodological tool allows to estimate the MSWI’s stack emission and relative profile of seventeen PCDD/F congeners over time. The approach was validated through a case study of a MSWI in Switzerland. The modeled congener profile achieved a Pearson correlation coefficient of 0.98 with measurements in fly ash washwater. Additionally, the simulated soil quantity (1,283–1,698 gTEQWHO−2022 or 1,115-1,419 gTEQ WHO−2005) fell within the same order of magnitude as the estimated quantity from measurements (425 gTEQ WHO−2022 or 371 gTEQ WHO−2005).
Artificial Intelligence Integration in Healthcare: Perspectives and Trends in a Survey of U.S. Health System Leaders
Authors: Guleria Shan , Guptill Janet , Kumar Ishmeet , McClintic Mia , Rojas Juan C.
Published: June 2024

Background
This study investigates the use and governance of artificial intelligence-derived predictive modeling (AIDPM) in the United States healthcare system.
Results
There are significant variations in how healthcare systems allocate resources and organize governance structures for AIDPM. A major obstacle is the lack of involvement of frontline clinicians in AIDPM governance.
Conclusions
Efforts to ensure health equity assessment in AIDPM commonly exclude frontline clinicians and patients, raising questions about the effectiveness of this pillar of AI governance.
A Prospective Study of Cigarette Smoking and Risk of 10-Years Incidence of Hypertension in men aged 20-74 years old; Yazd Healthy Heart Cohort Study (YHHC)
Authors: Namayandeh Seyedeh Mahdieh , Emadi Seyed hasan , Majidpour Fatemeh , Bafghi Seyed Mahmood Sadr , Soltani Mohammadhosein
Published: June 2024

The effects of cigarette smoking on blood pressure are complex, with evidence that smoking increases acute increase in blood pressure (BP), heart rate, risk of renovascular, malignant, and masked hypertension. We evaluated smoking status in phase I and hypertension incidence in males after 10 years using YHHC (Yazd Healthy Heart Cohort Study) data. All of normotensives participants enrolled the analysis. Univariate analysis was performed via Chi -square and student T tes and we employed a multivariable logistic regression model with the "backward" method to assess the risk of hypertension associated with smoking status while adjusting for other risk factors. out of total 446 male follow –uped during 10-years, 37 new case(31.9%) developed hypertension incidence in smoker men at the baseline. We found in Multivariate-adjusteda(aOR = 0.52,95%CI(0.29–0.94,P = 0.032) and Multivariate-adjustedb(aOR = 0.58,95%CI(0.31–1.08,P = 0.089) withStepwise Model selection variable Cigarette Smoking history don’t increase 10-years hypertension.we observed history of smoking associated with decrease hypertension incidence.
Is bladder paraganglioma a differential diagnosis of bladder lithiasis ? : Case report and review of the literature
Authors: Babty M , Maachi Y , Mehedra A , Cheddadi M , Derqaoui S , Slaoui A , Karmouni T , Bernoussi Z , khader K El , Koutani A , Attya A Iben
Published: June 2024

Paraganglioma or extra-adrenal pheochromocytoma is a rare entity, particularly in its bladder location. When functional, paragangliomas are easily recognised by their clinical presentation. The danger comes when it is non-functional or unusual, where serious intraoperative complications may occur. The authors report an atypical and silent presentation of bladder paraganglioma in a 39-year-old female patient who had undergone a left surrenalectomy for pheochromocytoma 16 years previously and consulted for lower urinary tract symptoms related to bladder lithiasis. Cystoscopy revealed a calcified bladder polyp. Complete trans-urethral resection of the tumour was performed without intraoperative complications. Histological analysis of the resection shavings concluded that the tumour was a bladder pheochromocytoma. Post-operative management was simple.
Memory-like natural killer cell and CD19-antibody based immunotherapy in combination with tyrosine-kinase inhibition of Ph(-like) acute lymphoblastic leukemia
Authors: Horstmann Martin , Eskandarian Zoya , Hauch Richard , Winterberg Dorothee , Grabellus Hjördis , Imelmann Carlotta , Schuster Sabrina , Heitmann Anna-Lena , Goos Marlene , Rudloff Khadija , Strauss Julia , Wolters-Eisfeld Gerrit , Nollau Peter , Klausz Katja , Schüller Ulrich , Peipp Matthias , Spohn Michael
Published: June 2024

Philadelphia-like acute lymphoblastic leukemia (Ph-like ALL) is a molecularly distinct tyrosine kinase-driven entity burdened with a high risk of relapsing disease and poor response toward combinatorial chemotherapy. Tyrosine kinase inhibitors (TKI) have been introduced into recent treatment protocols to improve the survival of patients with Ph-like ALL, yet preliminary data indicate subpar outcome. To advance treatment concepts for this genetic subtype of ALL, engineered antibody and CAR T-cell based immunotherapy has been proposed. Alternatively, the clinical use of natural killer cells endowed with a CAR or combined with leukemia epitope-directed antibodies is a conceivable strategy, which allows for an adoptive transfer of immune cells in an allogeneic setting with a low risk of graft-versus-host reaction. Here, we explored memory-like NK cells and Fc-enhanced CD19 antibody-dependent cell-mediated cytotoxicity (ADCC) in combination with TKI directed against in vitro models of kinase-driven leukemia. We demonstrate that the memory-like state of NK cells is determined by interleukin-mediated epigenetic reprogramming resulting in enhanced antileukemic effector functions. TKI differentially interfere with NK cell function and receptor repertoire, but CD19 antibody-mediated cytotoxicity operates ABL and JAK-independent allowing for simultaneous administration of memory-like NK cells, CD19 antibody, and specific TKI with high treatment efficacy in vitro.