bluuebunny/crossref_metadata_2025 huggingface dataset:
Recycling Feldspar Mining Waste as Buffering Agent for Acid Mine Drainage Mitigation
Authors: Grieco Giovanni , Cocomazzi Giuseppe , Naitza Stefano , Bussolesi Micol , Deidda Matteo Luca , Ferrari Elena Silvia , Destefanis Enrico
Published: May 2024

Acid mine drainage (AMD) prevention or remediation is a major issue of the environmental management of sulfide-bearing active and abandoned mining sites, the main sources of acidic waters being wastes and tailings. The present work intends to check a circular economy approach to such issues in the mining region of Sardinia, where environmental pollution, due to AMD, is a major concern. Tests were conducted on basic drainage-producing feldspar mining wastes that could be recycled as buffering agents of sulfide-bearing tailings. Among the sulfide-bearing abandoned mining sites investigated, Furtei epithermal gold deposit tailings are the most polluting and those that can better test the buffering agent efficacy. Buffering test results show that buffering to near-neutral conditions can be attained following steps similar to those of pure calcite buffer. The buffering potential of the recycled waste is due to both the buffer calcite content, which provides short-term buffering, enhanced by feldspar content that can provide long-term buffering. Buffered waters show a dramatic decrease in the concentration of most of the metals present in the leachate, down to conditions that meet the requirements for the discharge of industrial waters according to Italian legislation.
Structured-Light 3D Imaging Based on Vector Iterative Fourier Transform Algorithm
Authors: Zhang Runzhe , Qiao Siyuan , Luo Yixiong , Guo Yinghui , Li Xiaoyin , Zhang Qi , Fan Yulong , Zhao Zeyu , Luo Xiangang
Published: May 2024

Quasi-continuous-phase metasurfaces overcome the side effects imposed by high-order diffraction on imaging and can impart optical parameters such as amplitude, phase, polarization, and frequency to incident light at sub-wavelength scales with high efficiency. Structured-light three-dimensional (3D) imaging is a hot topic in the field of 3D imaging because of its advantages of low computation cost, high imaging accuracy, fast imaging speed, and cost-effectiveness. Structured-light 3D imaging requires uniform diffractive optical elements (DOEs), which could be realized by quasi-continuous-phase metasurfaces. In this paper, we design a quasi-continuous-phase metasurface beam splitter through a vector iterative Fourier transform algorithm and utilize this device to realize structured-light 3D imaging of a target object with subsequent target reconstruction. A structured-light 3D imaging system is then experimentally implemented by combining the fabricated quasi-continuous-phase metasurface illuminated by the vertical-cavity surface-emitting laser and a binocular recognition system, which eventually provides a new technological path for the 3D imaging field.
Strategy for Ensuring the Metrological Traceability of Nanoparticle Size Measurements by SEM
Authors: Feltin Nicolas , Delvallée Alexandra , Crouzier Loïc
Published: May 2024

The concept of measurement traceability is crucial for ensuring the data reliability and the comparability of measurement results provided by different instruments and operators. In the field of nanoparticle metrology, determining the size of nanoparticles using electron microscopy-based techniques remains a real challenge. In laboratory settings, the establishment of traceability regarding the instrument calibration procedures, the assessment of uncertainties associated with instruments/operators/samples/environments, as well as the complexities related to electron–sample interactions, are often neglected. In this article, we describe the calibration procedure set up at the LNE (Laboratoire National de métrologie et d’Essais) and propose an evaluation method for determining the uncertainties in measuring nanoparticle size by SEM (Scanning Electron Microscopy). This study investigates the impact of the energy of the primary electrons (PEs) generated by the electron beam and accelerating voltage on the reliability of size measurements. The convolution between the signals coming from a nanoparticle and the substrate on which the particle is deposited induces edge effects that can have a negative impact on the measurement results. Finally, a diagram describing the various stages involved in establishing traceability for SEM measurements of nanoparticle size is proposed to facilitate the work of future operators.
Two-Dimensional MoS2 Nanosheets Derived from Cathodic Exfoliation for Lithium Storage Applications
Authors: Martínez-Jódar Alberto , Villar-Rodil Silvia , Munuera José M. , Castro-Muñiz Alberto , Coleman Jonathan N. , Raymundo-Piñero Encarnación , Paredes Juan I.
Published: May 2024

The preparation of 2H-phase MoS2 thin nanosheets by electrochemical delamination remains a challenge, despite numerous efforts in this direction. In this work, by choosing appropriate intercalating cations for cathodic delamination, the insertion process was facilitated, leading to a higher degree of exfoliation while maintaining the original 2H-phase of the starting bulk MoS2 material. Specifically, trimethylalkylammonium cations were tested as electrolytes, outperforming their bulkier tetraalkylammonium counterparts, which have been the focus of past studies. The performance of novel electrochemically derived 2H-phase MoS2 nanosheets as electrode material for electrochemical energy storage in lithium-ion batteries was investigated. The lower thickness and thus higher flexibility of cathodically exfoliated MoS2 promoted better electrochemical performance compared to liquid-phase and ultrasonically assisted exfoliated MoS2, both in terms of capacity (447 vs. 371 mA·h·g−1 at 0.2 A·g−1) and rate capability (30% vs. 8% capacity retained when the current density was increased from 0.2 A·g−1 to 5 A·g−1), as well as cycle life (44% vs. 17% capacity retention at 0.2 A·g−1 after 580 cycles). Overall, the present work provides a convenient route for obtaining MoS2 thin nanosheets for their advantageous use as anode material for lithium storage.
Fabrication of WO3 Quantum Dots with Different Emitting Colors and Their Utilization in Luminescent Woods
Authors: Park Kwang Hyun , Kim Nam Chul , Song Sung Ho
Published: May 2024

With a rising interest in smart windows and optical displays, the utilization of metal oxides (MOs) has garnered significant attention owing to their high active sites, flexibility, and tunable electronic and optical properties. Despite these advantages, achieving precise tuning of optical properties in MOs-based quantum dots and their mass production remains a challenge. In this study, we present an easily scalable approach to generate WO3 quantum dots with diverse sizes through sequential insertion/exfoliation processes in solvents with suitable surface tension. Additionally, we utilized the prepared WO3 quantum dots in the fabrication of luminescent transparent wood via an impregnation process. These quantum dots manifested three distinct emitting colors: red, green, and blue. Through characterizations of the structural and optical properties of the WO3 quantum dots, we verified that quantum dots with sizes around 30 nm, 50 nm, and 70 nm showcase a monoclinic crystal structure with oxygen-related defect sites. Notably, as the size of the WO3 quantum dots decreased, the maximum emitting peak underwent a blue shift, with peaks observed at 407 nm (blue), 493 nm (green), and 676 nm (red) under excitation by a He-Cd laser (310 nm), respectively. Transparent woods infused with various WO3 quantum dots exhibited luminescence in blue/white emitting colors. These results suggest substantial potential in diverse applications, such as building materials and optoelectronics.
Magnet-Guided Temozolomide and Ferucarbotran Loaded Nanoparticles to Enhance Therapeutic Efficacy in Glioma Model
Authors: Thomas Reju George , Kim Subin , Tran Thi-Anh-Thuy , Kim Young Hee , Nagareddy Raveena , Jung Tae-Young , Kim Seul Kee , Jeong Yong Yeon
Published: May 2024

Background. The aim of the study was to synthesize liposomal nanoparticles loaded with temozolomide and ferucarbotran (LTF) and to evaluate the theranostic effect of LTF in the glioma model. Methods. We synthesized an LTF that could pass through the Blood Brain Barrier (BBB) and localize in brain tumor tissue with the help of magnet guidance. We examined the chemical characteristics. Cellular uptake and cytotoxicity studies were conducted in vitro. A biodistribution and tumor inhibition study was conduted using an in vivo glioma model. Results. The particle size and surface charge of LTF show 108 nm and −38 mV, respectively. Additionally, the presence of ferucarbotran significantly increased the contrast agent effect of glioma compared to the control group in MR imaging. Magnet-guided LTF significantly reduced the tumor size compared to control and other groups. Furthermore, compared to the control group, our results demonstrate a significant inhibition in brain tumor size and an increase in lifespan. Conclusions. These findings suggest that the LTF with magnetic guidance represents a novel approach to address current obstacles, such as BBB penetration of nanoparticles and drug resistance. Magnet-guided LTF is able to enhance therapeutic efficacy in mouse brain glioma.
Antimicrobial Activities of Natural Bioactive Polyphenols
Authors: Mandal Manas Kumar , Domb Abraham J.
Published: May 2024

Secondary metabolites, polyphenols, are widespread in the entire kingdom of plants. They contain one or more hydroxyl groups that have a variety of biological functions in the natural environment. These uses include polyphenols in food, beauty products, dietary supplements, and medicinal products and have grown rapidly during the past 20 years. Antimicrobial polyphenols are described together with their sources, classes, and subclasses. Polyphenols are found in different sources, such as dark chocolate, olive oil, red wine, almonds, cashews, walnuts, berries, green tea, apples, artichokes, mushrooms, etc. Examples of benefits are antiallergic, antioxidant, anticancer agents, anti-inflammatory, antihypertensive, and antimicrobe properties. From these sources, different classes of polyphenols are helpful for the growth of internal functional systems of the human body, providing healthy fats, vitamins, and minerals, lowering the risk of cardiovascular diseases, improving brain health, and rebooting our cellular microbiome health by mitochondrial uncoupling. Among the various health benefits of polyphenols (curcumin, naringenin, quercetin, catechin, etc.) primarily different antimicrobial activities are discussed along with possible future applications. For polyphenols and antimicrobial agents to be proven safe, adverse health impacts must be substantiated by reliable scientific research as well as in vitro and in vivo clinical data. Future research may be influenced by this evaluation.
Associations between Diabetes-Specific Medication Regimen Complexity and Cardiometabolic Outcomes among Underserved Non-Hispanic Black Adults Living with Type 2 Diabetes Mellitus
Authors: Wisseh Cheryl , Adinkrah Edward , Opara Linda , Melone Sheila , Udott Emem , Bazargan Mohsen , Shaheen Magda
Published: May 2024

Type 2 diabetes mellitus (T2DM) management and glycemic control in underserved non-Hispanic Black adults presents with multifaceted challenges: balancing the optimal complexity of antihyperglycemic medications prescribed, limited medication access due to socioeconomic status, medication nonadherence, and high prevalence of cardiometabolic comorbidities. This single-center, cross-sectional, retrospective chart analysis evaluated the association of Medication Regimen Complexity (MRC) with cardiometabolic outcomes (glycemic, atherogenic cholesterol, and blood pressure control) among non-Hispanic Black adults with type 2 diabetes. Utilizing 470 independent patient electronic health records, MRC and other covariates were examined to determine their associations with cardiometabolic outcomes. Chi-square tests of independence and multiple logistic regression were performed to identify associations between MRC and cardiometabolic outcomes. Our findings indicate significant negative and positive associations between MRC and glycemic control and atherogenic cholesterol control, respectively. However, there were no associations between MRC and blood pressure control. As diabetes MRC was shown to be associated with poor glycemic control and improved atherogenic cholesterol control, there is a critical need to standardize interdisciplinary diabetes care to include pharmacists and to develop more insurance policy interventions that increase access to newer, efficacious diabetes medications for historically marginalized populations.
Correction: Shutaleva, A. Epistemic Challenges in Neurophenomenology: Exploring the Reliability of Knowledge and Its Ontological Implications. Philosophies 2023, 8, 94
Authors: Shutaleva Anna
Published: May 2024

The author would like to make the following corrections to the published paper [...]
Parametric Optimization of FDM Process for PA12-CF Parts Using Integrated Response Surface Methodology, Grey Relational Analysis, and Grey Wolf Optimization
Authors: Almuflih Ali Saeed , Abas Muhammad , Khan Imran , Noor Sahar
Published: May 2024

Efficiently managing multiple process parameters is critical for achieving optimal performance in additive manufacturing. This study investigates the relationship between eight key parameters in fused deposition modeling (FDM) and their impact on responses like average surface roughness (Ra), tensile strength (TS), and flexural strength (FS) of carbon fiber-reinforced polyamide 12 (PA 12-CF) material. The study integrates response surface methodology (RSM), grey relational analysis (GRA), and grey wolf optimization (GWO) to achieve this goal. A total of 51 experiments were planned using a definitive screening design (DSD) based on response RSM. The printing process parameters, including layer thickness, infill density, and build orientation, significantly affect Ra, TS, and FS. GRA combines responses into a single measure, grey relational grade (GRG), and a regression model is developed. GWO is then employed to optimize GRG across parameters. Comparison with GRA-optimized parameters demonstrates GWO’s ability to discover refined solutions, reducing average surface roughness to 4.63 μm and increasing tensile strength and flexural strength to 88.5 MPa and 103.12 MPa, respectively. Practical implications highlight the significance of GWO in industrial settings, where optimized parameters lead to reduced costs and improved product quality. This integrated approach offers a systematic methodology for optimizing FDM processes, ensuring robustness and efficiency in additive manufacturing applications.
Verification of the Self-Healing Ability of PP-co-HUPy Copolymers in Epoxy Systems
Authors: Calabrese Elisa , Raimondo Marialuigia , Sorrentino Andrea , Russo Simona , Longo Pasquale , Mariconda Annaluisa , Longo Raffaele , Guadagno Liberata
Published: May 2024

This work concerns the verification of the self-healing ability of PP-co-HUPy copolymers dispersed in epoxy systems. PP is the acronym for the Poly-PEGMA polymer, and HUPy refers to the HEMA-UPy copolymers based on ureidopyrimidinone (UPy) moieties. In particular, this work aims to verify whether this elastomer characterized by an intrinsic self-healing ability can activate supramolecular interactions among polymer chains of an epoxy resin, as in the elastomer alone. The elastomer includes a class of polyethylene glycol monomethyl ether methacrylate-based copolymers, with different percentages of urea-N-2-amino-4-hydroxy-6-methyl pyrimidine-N’-(hexamethylene-n-carboxyethyl methacrylate) (HEMA-UPy) co-monomers. The self-healing capability of these copolymers based on possible quadruple hydrogen bond interactions between polymer chains has been verified. The formulated epoxy samples did not show self-healing efficiency. This can be attributed to the formation of phase segregation that originates during the curing process of the samples, although the PP-co-HUPy copolymers are completely soluble in the liquid epoxy matrix EP. The morphological investigation highlighted the presence of crystals of PP-co-HUPy copolymers, which are in greater quantity in the sample containing the highest weight percentage (7.8 wt%) of HUPy units. Furthermore, the crystals act as promotors for increasing the curing degree (DC) of the epoxy systems containing HUPy units. DC goes from 91.6% for EP to 96.1% and 95.4% for the samples containing weight percentages of 2.5 and 7.8 wt% of HUPy units, respectively. Dynamic mechanical analysis (DMA) shows storage modulus values for epoxy systems containing PP-co-HUPy units lower than that of the unfilled resin EP. The values of maximum in Tan δ (Tg), representing the temperature at which the glass transition occurs, are 220 for the unfilled resin EP, 228 for the sample containing 2.5 wt% of HEMA-UPy units, and 211 for the sample containing 7.8 wt% of HEMA-UPy units.
Three-Dimensional-Printed Composite Scaffolds Containing Poly-ε-Caprolactone and Strontium-Doped Hydroxyapatite for Osteoporotic Bone Restoration
Authors: Codrea Cosmin Iulian , Lincu Daniel , Ene Vladimir Lucian , Nicoară Adrian Ionuț , Stan Miruna Silvia , Ficai Denisa , Ficai Anton
Published: May 2024

A challenge in tissue engineering and the pharmaceutical sector is the development of controlled local release of drugs that raise issues when systemic administration is applied. Strontium is an example of an effective anti-osteoporotic agent, used in treating osteoporosis due to both anti-resorptive and anabolic mechanisms of action. Designing bone scaffolds with a higher capability of promoting bone regeneration is a topical research subject. In this study, we developed composite multi-layer three-dimensional (3D) scaffolds for bone tissue engineering based on nano-hydroxyapatite (HA), Sr-containing nano-hydroxyapatite (SrHA), and poly-ε-caprolactone (PCL) through the material extrusion fabrication technique. Previously obtained HA and SrHA with various Sr content were used for the composite material. The chemical, morphological, and biocompatibility properties of the 3D-printed scaffolds obtained using HA/SrHA and PCL were investigated. The 3D composite scaffolds showed good cytocompatibility and osteogenic potential, which is specifically recommended in applications when faster mineralization is needed, such as osteoporosis treatment.
Classification Strategy for Power Quality Disturbances Based on Variational Mode Decomposition Algorithm and Improved Support Vector Machine
Authors: Gao Le , Wang Jinhao , Zhang Min , Zhang Shifeng , Wang Hanwen , Wang Yang
Published: May 2024

With the continuous improvement in production efficiency and quality of life, the requirements of electrical equipment for power quality are also increasing. Accurate detection of various power quality disturbances is an effective measure to improve power quality. However, in practical applications, the dataset is often contaminated by noise, and when the dataset is not sufficient, the computational complexity is too high. Similarly, in the recognition process of artificial neural networks, the local optimum often occurs, which ultimately leads to low recognition accuracy for the trained model. Therefore, this article proposes a power quality disturbance classification strategy based on the variational mode decomposition (VMD) and improved support vector machine (SVM) algorithms. Firstly, the VMD algorithm is used for preprocessing disturbance denoising. Next, based on the analysis of typical fault characteristics, a multi-SVM model is used for disturbance classification identification. In order to improve the recognition accuracy, the improved Grey Wolf Optimization (IGWO) algorithm is used to optimize the penalty factor and kernel function parameters of the SVM model. The results of the final case study show that the classification accuracy of the proposed method can reach over 98%, and the recognition accuracy is higher than that of the other models.
Oil Removal Technology for Water Injection in Low-Permeability Reservoirs: A Micro-Vortex Flow Approach
Authors: Zhao Dawei , Xie Weihong , Zhu Jingyi , Li Bing , Wang Lirong , Chen Tao , Sheng Yuxin , Huang Xiujie
Published: May 2024

Gravity settling is a widely employed technology that removes oil from produced water in oilfields. However, with the transition of reservoir development to low-permeability reservoirs, conventional produced water settling tanks face limitations in the treatment efficiency and coagulant dosage. This study presents an innovative approach that optimizes sedimentation tank structures and integrates micro-vortex flow technology to enhance coagulation and flocculation. Through chemical dosage experiments, comparative experiments, and long-term observation, the micro-vortex flow reactor demonstrates a 9.4% increase in oil removal efficiency while reducing the coagulant dosage by 30.0%. The MOR equipment achieved a 20.5% higher oil removal efficiency than conventional methods while maintaining effluent oil and suspended solids below 20 mg/L. The long-term observation experiment of MOR equipment further highlights oil removal efficiency of 94.2% and the micro-vortex reactor’s excellent anti-pollution performance. The MOR equipment significantly reduces the land occupancy area by over 50% compared to conventional methods, thanks to the implementation of micro-vortex flow technology that effectively addresses the limitations associated with traditional settling tanks. This study contributes to advancing efficient and sustainable practices in waterflooding reservoirs, particularly for meeting stringent standards of water injection in low-permeability oilfields.
ARM Cortex Simulation Design for Trajectory Curves Evaluation of Collaborative Robots’ Tungsten Inert Gas Welding
Authors: Gao Shan , Geng Hua , Ge Yaqiong , Zhang Wenbin
Published: May 2024

An ARM Cortex simulation system for collaborative welding robots is presented in this paper. The components of the ARM Cortex SoC for embedded robot control, an OpenGL ES with image rendering, and a 3D geometry engine OpenCasCade for modeling are integrated for the purposes of simulating system self-controllability and cost effectiveness. This simulation of a collaborative welding robot achieved convenience while meeting the performance requirements; meanwhile, the auxiliary design was able to mark the trajectory of the robot’s end effector and reveal the collaborative robot’s inverse kinematic parameters, namely the position and Euler angle. An ARM Linux X11 Window environment that was set to create a 3D simulation rendering algorithm was built simultaneously. Then, the STEP model of the robot was loaded by using the OpenCasCade functionality. After that, the robot model and complex spline surface could be visualized by using the Qt QGLWidget. Finally, the correctness of the kinematic algorithm was verified by conducting simulations and analyzing the robot’s kinematics through the simulation results, which could verify the expected design and provide a set of fundamental samples for the robot trajectory industry regarding welding applications.
Strategies for Optimizing Shut-In Time: New Insights from Shale Long-Term Hydration Experiments
Authors: Zeng Bo , Dong Enjia , Yao Zhiguang , Song Yi , Xiong Zhuang , Huang Yongzhi , Gou Xiaoyan , Hu Xiaodong
Published: May 2024

In the process of hydraulic fracturing, fracturing fluid invades the formation and reacts with shale. Water-sensitive clay minerals swell when exposed to water. This results in a change in the mechanical properties of shale. However, the influences of a long-term water–shale reaction on mechanical properties are still unclear, and an optimization strategy of the shut-in time is required. In this paper, an optimization strategy for the shut-in time based on a shale long-term hydration experiment is proposed. In this paper, the water–shale reaction is simulated by laboratory experiments under normal temperature and pressure. The experiments are performed based on specimens from a shale outcrop. Clay and mineral composition, Young’s modulus, surface hardness, and tensile strength parameters are measured at 30-day intervals for 90 days. A CT scan was performed for 180 days. The experimental results show that the mass fraction of clay increased by 14.719%. In addition, significant argillaceous shedding occurs during the water–shale reaction period of 3–4 months. By testing the tensile strength, uniaxial compression decreases by 90.481% in three months. The Young’s modulus of mineral points decreases to 40% after reaction for three months. The shale has softened. The softening process is nonlinear and there are inflection points. The diffusion behavior of clay minerals and the expansion behavior of new fractures are observed by CT during 3–4 months of water–shale reaction. The results show that the shale softening and pore fracture structure changes are non-linear and heterogeneous, resulting in critical water–shale reaction time. According to the experimental results, the critical water–shale reaction time can be summarized. In this time, the fracture volume increases significantly, which is conducive to increasing oil and gas production. However, the fracture volume is not significantly increased by prolonging the shut-in time. The experimental results can guide the design of hydraulic fracturing shut-in time of shale reservoirs.
Numerical Simulation of Hydraulic Fracture Propagation on Multilayered Formation Using Limited Entry Fracturing Technique
Authors: Liu Hexing , Ji Wenjuan , Huang Yi , Zhang Wandong , Yang Junlong , Xu Jing , Mei Mingyang
Published: May 2024

Hydraulic fracturing is one of the most effective stimulation methods for unconsolidated sandstone reservoirs. However, the design of hydraulic fracturing must take into account the mechanical and stress properties of different geological formations between layers. In this paper, a three-dimensional coupled fluid-solid model using the finite element method is developed to investigate multiple vertical fractures at different depths along a vertical wellbore under different geological and geomechanical conditions. The finite element model does not require further refinement of any new cracks, requiring much smaller degrees of freedom and higher computational efficiency. In addition, new elements were used to account for local pressure drop due to perforation entry friction along the vertical wellbore. Numerical simulation results indicate that hydraulic fracture connections are observed from adjacent layers. Furthermore, the low stress contrast and high Young’s modulus between the layers increases the likelihood of multiple fracture connections. Higher fluid leakage rates increase the likelihood of fracture branching, but decrease the area of fracture coverage near the wellbore. Increasing fluid viscosity is effective in improving the area of fracture coverage near the wellbore. These findings are useful for the design of hydraulic fracturing in multi-layered formations in unconsolidated sandstone formations.
A Case Study of Bank Equity Valuation Methods Employed by South African, Nigerian and Kenyan Equity Researchers
Authors: Moyo Vusani , Obadire Ayodeji Michael
Published: May 2024

The valuation of banks is inherently complicated because of the uncertainties arising from their information opaqueness and inherent risks. Unlike non-banking firms, banks require specialised equity-side valuation approaches. This study addresses a gap in the literature by examining valuation methods used by bank equity researchers. The study used a total of 201 reports on South African banks (2018–2023), 56 reports on Nigerian banks (2018–2023), and 27 reports on Kenyan banks (2018–2023) to investigate the bank equity valuation methods utilised by analysts in the employ of Investec Ltd. and Standard Bank Group Ltd. The study’s findings show that Investec’s South African analysts predominantly used the warranted equity method, based on book value (BV), and return on equity (ROE), for valuing shares throughout the South African, Nigerian, and Kenyan banks surveyed. Furthermore, Standard Bank Group’s analysts employed this method, incorporating tangible net asset value (tNAV) and return on tangible equity (ROTE), for South African and Nigerian banks, but in Kenya their analysts used the residual income model to value the equities of the five Kenyan banks they covered. These findings suggest that the warranted equity method and the residual income model are the mostly used bank equity valuation methods in South Africa, Nigeria, and Kenya. The study concludes with relevant recommendations, offering significant insights for banks, regulators, and investors to make knowledgeable decisions concerning equity valuation.
School Dropout in Satellite Towns around Bucharest, Romania
Authors: Petre Florin-Bogdan , Teodorescu Camelia , Cioclu Alexandra
Published: May 2024

School dropout is a pressing social problem that stems from systemic inadequacies in the education system and socio-economic background. The aim of this study was to analyze how the travel time and financial difficulties impact school dropout in satellite towns near Bucharest, the capital of Romania. Data on dropout rates in recent years were provided by the Ilfov County General School Inspectorate and were supplemented by 30 semi-structured interviews with the parents, caregivers, or the legal representatives of students who have dropped out of school or are at risk of dropping out. The study’s findings reveal significant correlations between the travel time to school, familial financial situation, and attitudes towards education, impacting dropout rates across various satellite towns. Addressing the challenge of school dropout promises societal improvement and empowers policymakers to enact more inclusive policies benefiting all members of society.
Solar Energy Systems Design Using Immersive Virtual Reality: A Multi-Modal Evaluation Approach
Authors: AlQallaf Noor , AlQallaf Ali , Ghannam Rami
Published: May 2024

As the demand for renewable energy sources continues to increase, solar energy is becoming an increasingly popular option. Therefore, effective training in solar energy systems design and operation is crucial to ensure the successful implementation of solar energy technology. To make this training accessible to a wide range of people from different backgrounds, it is important to develop effective and engaging training methods. Immersive virtual reality (VR) has emerged as a promising tool for enhancing solar energy training and education. In this paper, a unique method is presented to evaluate the effectiveness of an immersive VR experience for solar energy systems design using a multi-modal approach that includes a detailed analysis of user engagement. To gain a detailed analysis of user engagement, the VR experience was segmented into multiple scenes. Moreover, an eye-tracker and wireless wearable sensors were used to accurately measure user engagement and performance in each scene. The results demonstrate that the immersive VR experience was effective in improving users’ understanding of solar energy systems design and their ability to perform complex tasks. Moreover, by using sensors to measure user engagement, specific areas that required improvement were identified and insights for enhancing the design of future VR training experiences for solar energy systems design were provided. This research not only advances VR applications in solar energy education but also offers valuable insights for designing effective and engaging training modules using multi-modal sensory input and real-time user engagement analytics.
Resistance Training Causes the Stretch-Induced Force Deficit—A Randomized Cross-Over Study
Authors: Warneke Konstantin , Turau Katharina , Lohmann Lars Hubertus , Hillebrecht Martin , Behm David G. , Konrad Andreas , Schmidt Tobias
Published: May 2024

Purpose: Stretch-induced force deficit suggests an acute stretch-specific strength capacity loss, which is commonly attributed to EMG reductions. Since those deficits could also be attributed to general fatigue induced by overloading the muscle, this study aimed to compare stretching with an exhausting calf raise programme to compare strength and stretching responses. Method: This study included 16 participants with different, high-duration calf muscle stretching effects (10, 20, 30 min of stretching) with resistance training (RT) (3 × 12 repetitions) performed until muscle failure, by using a cross-over study design with pre-post comparisons. Strength was tested via isometric plantar flexor diagnostics, while flexibility was assessed using the knee-to-wall test (KtW) and an isolated goniometer test. Results: Using a three-way ANOVA, RT strength decreases were greater compared to 10 and 20 min of stretching (p = 0.01–0.02), but similar to those of 30 min of stretching. ROM in the KtW showed no specific stretch-induced increases, while only the stretching conditions enhanced isolated tested ROM (p < 0.001–0.008). No RT-related isolated ROM increases were observed. Conclusions: The results showed both interventions had similar effects on strength and ROM in the calf muscles. More holistic explanatory approaches such as fatigue and warm-up are discussed in the manuscript and call for further research.
The Effect of Physical Activity Levels on Cognitive Performance: Research in Portuguese Adolescents
Authors: Rodrigues Ana , Antunes Hélio , Sabino Bebiana , Sousa Duarte , Correia Ana Luísa , Alves Ricardo , Lopes Hélder
Published: May 2024

The literature unequivocally acknowledges the numerous health benefits that physical activity (PA) provides. However, in other variables, such as cognitive performance (CP), the PA characteristics required to elicit favorable benefits remain controversial, particularly among adolescents. The aim was to investigate the evolution of CP in adolescents over the school year, as well as the role of regular PA levels. The study included 366 adolescents (boys n = 154), between 12 and 20 years old (15.46 ± 1.63), from middle school (n = 123) and high school (n = 243). CP was assessed through a face-to-face interview employing the Cognitive Telephone Screening Instrument. The variation in CP (∆CP) was determined by the difference between the value of the final assessment (end of the school year) and the initial assessment (start of the school year). PA was assessed using accelerometry (ActiGraph GT3X+). The CP score improved from the initial to the final assessment (37.80 ± 9.26 vs. 40.45 ± 10.05) (t = −6.135; p < 0.001; Glass’s Delta = 0.37. Multiple linear regression revealed that age (ß = −0.332; t = −4.255; p < 0.001) and high-intensity PA (ß = 0.283; t = 3.627; p < 0.001) accounted for 17.2% of the variation in ∆CP. CP improved significantly over the school year, emphasizing the significance of age and vigorous PA in ∆CP in adolescents.
Retrograde Endovascular Recanalization of the Superior Mesenteric Artery for the Treatment of Acute Bowel Ischemia: Case Report
Authors: Latacz Pawel , Piekorz Piotr , Simka Marian
Published: May 2024

Acute bowel ischemia is a life-threatening abdominal emergency. In many patients, percutaneous endovascular repair of visceral arteries in an antegrade direction across occluding lesions is challenging and sometimes not possible. We present the case of technically successful percutaneous retrograde recanalization of an occluded superior mesenteric artery in a critically ill 82-year-old patient. The superior mesenteric artery was recanalized via the branches of the celiac trunk; the guidewires were navigated to the target artery through the gastroduodenal and pancreaticoduodenal arteries. Retrograde percutaneous recanalization of the superior mesenteric artery is technically feasible, even in hemodynamically unstable patients.
Evaluation and Prediction of Regional Innovation Ecosystem from the Perspective of Ecological Niche: Nine Cities in Hubei Province, China as the Cases
Authors: Xiao Jiaxing , Liao Yang , Hou Renyong , Peng Weihua , Dan Haijian
Published: May 2024

Based on niche theory, this paper constructs an evaluation index system for regional innovation ecosystem suitability from four aspects: innovation benefits, innovation technology, innovation culture, and innovation policy. The niche evaluation model is used to calculate and compare the suitability and evolutionary momentum of the innovation ecosystems in nine prefecture-level cities in Hubei Province from 2017 to 2022. Using the grey prediction model GM (1,1), the development of niche suitability for the nine prefecture-level cities in Hubei Province over the next five years is predicted. The results showed that, from the perspective of the niche, the overall suitability of the innovation niches in the nine prefecture-level cities of Hubei Province is relatively low, with higher evolutionary momentum, and the two exhibited a reverse development trend. The forecast results indicated that the suitability of the innovation niches in the nine prefecture-level cities of Hubei Province will follow different development trends in the next five years, with central cities showing higher development than non-central cities. Accordingly, this study provides a more scientific method for the evaluation, monitoring, forecasting, and improvement of regional innovation ecosystems at the city level. It supports policy formulation and strategic planning for the nine prefecture-level cities in Hubei Province and other regions from the aspects of innovation benefits, innovation technology, innovation culture, and innovation policy. At the same time, this study also provides new research pathways for the academic community, encouraging scholars to adopt multidisciplinary and multi-faceted approaches to explore the complexity and dynamics of regional innovation ecosystems in depth. It utilizes this information to optimize and adjust regional innovation policies to better adapt to the needs of global innovation competition.
Intelligent Cane for Assisting the Visually Impaired
Authors: Panazan Claudiu-Eugen , Dulf Eva-Henrietta
Published: May 2024

Those with visual impairments, including complete blindness or partial sight loss, constitute a significant global population. According to estimates by the World Health Organization (WHO), there are at least 2.2 billion people worldwide who have near or distance vision disorders. Addressing their needs is crucial. Introducing a smart cane tailored for the blind can greatly improve their daily lives. This paper introduces a significant technical innovation, presenting a smart cane equipped with dual ultrasonic sensors for obstacle detection, catering to the visually impaired. The primary focus is on developing a versatile device capable of operating in diverse conditions, ensuring efficient obstacle alerts. The strategic placement of ultrasonic sensors facilitates the emission and measurement of high-frequency sound waves, calculating obstacle distances and assessing potential threats to the user. Addressing various obstacle types, two ultrasonic sensors handle overhead and ground-level barriers, ensuring precise warnings. With a detection range spanning 2 to 400 cm, the device provides timely information for user reaction. Dual alert methods, including vibrations and audio signals, offer flexibility to users, controlled through intuitive switches. Additionally, a Bluetooth-connected mobile app enhances functionality, activating audio alerts if the cane is misplaced or too distant. Cost-effective implementation enhances accessibility, supporting a broader user base. This innovative smart cane not only represents a technical achievement but also significantly improves the quality of life for visually impaired individuals, emphasizing the social impact of technology. The research underscores the importance of technological research in addressing societal challenges and highlights the need for solutions that positively impact vulnerable communities, shaping future directions in research and technological development.
miR–122–5p Promotes Cowshed Particulate Matter2.5-Induced Apoptosis in NR8383 by Targeting COL4A1
Authors: Sun Yize , Sun Ke , Ma Zhenhua , Zhang Xiqing , Du Xiaohui , Jia Yunna , Zhu Yanbin , Inam Muhammad , Gao Yunhang , Basang Wangdui
Published: May 2024

It is well known that Particulate Matter2.5 (PM2.5) has a major adverse effect on the organism. However, the health hazards of livestock farm PM2.5 to humans and animals are not yet known, and the role of miRNAs in the cellular damage induced by livestock farm PM2.5 is also unclear. Therefore, our study used cowshed PM2.5 to stimulate rat alveolar macrophage NR8383 to construct an in vitro injury model to investigate the effect of miR–122–5p on PM2.5-induced apoptosis in the NR8383. The level of apoptosis was quantified by flow cytometry and Hoechst 33342/PI double staining. Furthermore, the potential target gene Collagen type IV alpha (COL4A1) of miR–122–5p was identified through the use of bioinformatics methods. The results demonstrated a decline in cell viability and an increase in apoptosis with rising PM2.5 concentrations and exposure durations. The transfection of miR–122–5p mimics resulted in an upregulation of the pro-apoptotic protein Bcl–xL/Bcl–2 and activation of cleaved caspase–3 while inhibiting the anti-apoptotic protein B–cell lymphoma–2. The experimental data indicate that miR–122–5p is involved in the apoptotic process by targeting COL4A1. Furthermore, the overexpression of COL4A1 was observed to enhance the PM2.5-activated PI3K/AKT/NF–κB signaling pathway, which contributed to the inhibition of apoptosis. This finding offers a promising avenue for the development of therapeutic strategies aimed at mitigating cellular damage induced by PM2.5 exposure.
Temporal and Spatial Variation of Toxic Metal Concentrations in Cultivated Soil in Jiaxing, Zhejiang Province, China: Characteristics and Mechanisms
Authors: Cao Mengzhuo , Jia Yanbo , Lu Xin , Huang Jinfa , Yao Yanlai , Hong Leidong , Zhu Weijing , Wang Weiping , Zhu Fengxiang , Hong Chunlai
Published: May 2024

The toxic metal (As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn) pollution in 250 agricultural soil samples representing the urban area of Jiaxing was studied to investigate the temporal and spatial variations. Compared to the early 1990s, the pollution level has increased. Industry and urbanization were the main factors causing toxic metal pollution on temporal variation, especially the use of feed containing toxic metals. The soil types and crop cultivation methods are the main factors causing toxic metal pollution on spatial variation. Although the single-factor pollution indices of all the toxic metals were within the safe limits, as per the National Soil Environmental Quality Standard (risk screening value), if the background values of soil elements in Jiaxing City are used as the standard, the pollution index of all the elements surveyed exceeds 1.0, reaching a level of mild pollution. The soil samples investigated were heavily contaminated with toxic metal compounds, and their levels increased over time. This situation poses potential ecological and health risks.
Global Trends and Hotspots in Research on the Health Risks of Organophosphate Flame Retardants: A Bibliometric and Visual Analysis
Authors: Du Zhiyuan , Ruan Yuanyuan , Chen Jiabin , Fang Jian , Xiao Shuo , Shi Yewen , Zheng Weiwei
Published: May 2024

Background: Organophosphate flame retardants (OPFRs) are compounds with a wide range of industrial and commercial applications and are mainly used as flame retardants and plasticizers. The global consumption of OPFRs has risen rapidly in recent decades, and they have been widely detected in environmental media. Unfortunately, OPFRs have been associated with many adverse health outcomes. The issue of the health risks of OPFRs is attracting increasing attention. Therefore, there is a need to review the current state of research and trends in this field to help researchers and policymakers quickly understand the field, identify new research directions, and allocate appropriate resources for further development of the OPFR health risk research field. Methods: This study statistically analyzed 1162 relevant publications included in the Web of Science Core Collection from 2003–2023. The internal and external features of the literature, such as publication trends, countries, authors, journals, and keywords, were quantitatively analyzed and visually presented to identify the research hotspots, compositions, and paradigms of the field and to horizontally and vertically analyze the development trends and structural evolution of the field. Results: The development of the field can be divided into three stages, and the field entered a period of rapid development in 2016. China (649 papers) is the most prolific country, followed by the United States (188 papers). The authors STAPLETON HM and WANG Y have the highest combined impact. International collaboration between countries and researchers still needs to be strengthened. Science of The Total Environment is the most frequently published journal (162 papers), and Environmental Science and Technology is the most frequently cited journal (5285 citations). Endocrine disruption, developmental toxicity, and neurotoxicity are the health effects of greatest interest. Conclusions: Future research is expected to be multidisciplinary, and research hotspots may involve a comprehensive assessment of OPFR exposure in the population, exploration of the mechanisms of endocrine-disrupting effects and in vivo metabolic processes, and examination of the health effects of OPFR metabolites.
Genome-Wide Transcriptional Roles of KSHV Viral Interferon Regulatory Factors in Oral Epithelial Cells
Authors: Jang Seung Jin , Atyeo Natalie , Mietzsch Mario , Chae Min Y. , McKenna Robert , Toth Zsolt , Papp Bernadett
Published: May 2024

The viral interferon regulatory factors (vIRFs) of KSHV are known to dysregulate cell signaling pathways to promote viral oncogenesis and to block antiviral immune responses to facilitate infection. However, it remains unknown to what extent each vIRF plays a role in gene regulation. To address this, we performed a comparative analysis of the protein structures and gene regulation of the four vIRFs. Our structure prediction analysis revealed that despite their low amino acid sequence similarity, vIRFs exhibit high structural homology in both their DNA-binding domain (DBD) and IRF association domain. However, despite this shared structural homology, we demonstrate that each vIRF regulates a distinct set of KSHV gene promoters and human genes in epithelial cells. We also found that the DBD of vIRF1 is essential in regulating the expression of its target genes. We propose that the structurally similar vIRFs evolved to possess specialized transcriptional functions to regulate specific genes.