bluuebunny/crossref_metadata_2025 huggingface dataset:
Deep Learning Ensemble Model for the Prediction of Traffic Accidents Using Social Media Data
Authors: Gutierrez-Osorio Camilo , González Fabio A. , Pedraza Cesar Augusto
Published: August 2022

Traffic accidents are a major concern worldwide, since they have a significant impact on people’s safety, health, and well-being, and thus, they constitute an important field of research on the use of state-of-the-art techniques and algorithms to analyze and predict them. The study of traffic accidents has been conducted using the information published by traffic entities and road police forces, but thanks to the ubiquity and availability of social media platforms, it is possible to have detailed and real-time information about road accidents in a given region, which allows for detailed studies that include unrecorded road accident events. The focus of this paper is to propose a model to predict traffic accidents using information gathered from social media and open data, applying an ensemble Deep Learning Model, composed of Gated Recurrent Units and Convolutional Neural Networks. The results obtained are compared with baseline algorithms and results published by other researchers. The results show promising outcomes, indicating that in the context of the problem, the proposed ensemble Deep Learning model outperforms the baseline algorithms and other Deep Learning models reported by literature. The information provided by the model can be valuable for traffic control agencies to plan road accident prevention activities.
Moiré-like Superlattice Generated van Hove Singularities in a Strained CuO2 Double Layer
Authors: Sboychakov Artem O. , Kugel Kliment I. , Bianconi Antonio
Published: August 2022

While it is known that the double-layer Bi2Sr2CaCu2O8+y (BSCCO) cuprate superconductor exhibits a one-dimensional (1D) incommensurate superlattice (IS), the effect of IS on the electronic structure remains elusive. Following the recent shift of interest from an underdoped phase to optimum and overdoped phases in BSCCO by increasing the hole doping x, controlled by the oxygen interstitials concentration y, here we focus on the multiple splitting of the density of states (DOS) peaks and emergence of higher order van Hove singularities (VHS) due to the 1D incommensurate superlattice. It is known that the 1D incommensurate wave vector q=ϵb (where b is the reciprocal lattice vector of the orthorhombic lattice) is controlled by the misfit strain between different atomic layers in the range 0.209–0.215 in BSCCO and in the range 0.209–0.25 in Bi2Sr2Ca1−xYxCu2O8+y (BSCYCO). This work reports the theoretical calculation of a complex pattern of VHS due to the 1D incommensurate superlattice with large 1D quasi-commensurate supercells with the wave vector ϵ=9/η in the range 36>η>43. The similarity of the complex VHS splitting and appearing of higher order VHS in a mismatched CuO2 bilayer with VHS due to the moiré lattice in strained twisted bilayer graphene is discussed. This makes a mismatched CuO2 bilayer quite promising for constructing quantum devices with tuned physical characteristics.
Characterization of Mn-Doped PIN-PMN-PT Single Crystal Grown by Continuous-Feeding Bridgman Method
Authors: Echizenya Kazuhiko , Noda Naoki , Noro Hisato
Published: August 2022

Mn-doped Pb(In1/2Nb1/2)O3-Pb(Mg1/3Nb2/3)O3-PbTiO3 (Mn:PIN-PMN-PT) single crystals are attractive piezoelectric materials owing to their high mechanical quality factor. However, the single crystal boules grown by the conventional Bridgman method show compositional variation along the growth direction. In particular, the Mn content exhibits large variation due to its severe segregation. To improve the compositional uniformity, we applied the continuous-feeding Bridgman method to the growth of a Mn:PIN-PMN-PT single crystal boule. Then, the composition and property distributions of the boule along the growth direction were evaluated. The results showed that excellent composition and property uniformity were carried out over 80mm in boule length. The ranges of the electromechanical coupling coefficient (k33) and the piezoelectric coefficient (d33) were 0.931–0.934 and 1352–1517 pC/N, respectively. The ranges of the mechanical quality factor (Qm31) and the depolarization field (Ed) were 417–535 and 785–859 V/mm, respectively. The Qm31 and the Ed values were higher than those of the non-doped PIN-PMN-PT single crystals. The continuous-feeding Bridgman method is therefore an effective technique for improving the uniformity of the Mn content. As a result, the Mn:PIN-PMN-PT single crystal grown by the continuous-feeding Bridgman method possesses excellent property uniformity with characteristics suitable for high power piezoelectric applications.
Experimental Investigation of Phase Equilibria in the Ti—Al—Zr System at 1000–1300 °C
Authors: Kahrobaee Zahra , Rashkova Boryana , Hauschildt Katja , Palm Martin
Published: August 2022

Four partial isothermal sections of the Ti—Al—Zr system up to 60 at. % Al and 30 at. % Zr were experimentally established between 1000–1300 °C. Six heat-treated alloys were analysed by scanning electron microscopy, transmission electron microscopy, electron probe microanalysis, conventional and high-energy X-ray diffraction, and differential thermal analysis. Phase equilibria were determined between B2-ordered (β0), βTi,Zr, αTi, Ti3Al, TiAl, and ZrAl2.
On the Definition of Phase Diagram
Authors: Dziubek Kamil Filip
Published: August 2022

A phase diagram, which is understood as a graphical representation of the physical states of materials under varied temperature and pressure conditions, is one of the basic concepts employed in high-pressure research. Its general definition refers to the equilibrium state and stability limits of particular phases, which set the stage for its terms of use. In the literature, however, a phase diagram often appears as an umbrella category for any pressure–temperature chart that presents not only equilibrium phases, but also metastable states. The current situation is confusing and may lead to severe misunderstandings. This opinion paper reviews the use of the “phase diagram” term in many aspects of scientific research and suggests some further clarifications. Moreover, this article can serve as a starting point for a discussion on the refined definition of the phase diagram, which is required in view of the paradigm shift driven by recent results obtained using emerging experimental techniques.
Warmer and Poorer: The Fate of Alpine Calcareous Grasslands in Central Apennines (Italy)
Authors: Varricchione Marco , Carranza Maria Laura , Di Cecco Valter , Di Martino Luciano , Stanisci Angela
Published: August 2022

Global change threatens alpine biodiversity and its effects vary across habitat types and biogeographic regions. We explored vegetation changes over the last 20 years on two Mediterranean alpine calcareous grasslands in central Apennines (Italy): stripped grasslands (EUNIS code E4.436) with Sesleria juncifolia growing on steep slopes, and wind edge swards (EUNIS code E4.42) with Carex myosuroides. Based on a re-visitation of 25 vegetation plots of 4 × 4 m, we assessed changes in overall and endemic plant species cover and richness by nonparametric Kruskal–Wallis test. We explored changes in structure and ecology using growth forms and Landolt indicators for temperatures. We identified species’ contribution to temporal changes using the similarity percentage procedure (SIMPER). The results evidenced a significant decline in all species cover and richness on both plant communities with a significant decline in alpine and endemic species and in hemicryptophytes with rosette and scapose ones on stripped grasslands, as well as a decline in subalpine and suffruticose chamaephytes species on wind edge swards. Such biodiversity loss, so far observed only in the warmest and Southern Mediterranean summits of Europe, is likely attributable to the combined effect of higher temperatures; the increase in the vegetative period; and the decrease in water availability, which is particularly severe in calcareous regions. Our study suggested the vulnerability of the analyzed alpine ecosystems to global change and the importance of monitoring activities to better understand vegetation trends and adaptation strategies in subalpine, alpine, and nival ecosystems.
Diagnostic Performance of Neutrophil to Lymphocyte Ratio, Monocyte to Lymphocyte Ratio, Platelet to Lymphocyte Ratio, and Platelet to Mean Platelet Volume Ratio in Periprosthetic Hip and Knee Infections: A Systematic Review and Meta-Analysis
Authors: Festa Enrico , Ascione Tiziana , Bernasconi Alessio , Di Gennaro Donato , Basso Morena Anna , Guarino Amedeo , Balato Giovanni
Published: August 2022

The current literature on the diagnosis of periprosthetic joint infection provides controversial evidence on the diagnostic accuracy of MLR, NLR, PVR, and PLR. Therefore, this critical literature search and meta-analysis was aimed to summarize the diagnostic accuracy of these biomarkers for the diagnosis of hip and knee prosthetic infection. According to the PRISMA flowchart, we searched MEDLINE, Scopus, and Web of Science, for studies on these ratios for diagnosing PJI. Sensitivity, specificity, positive and negative likelihood ratio, diagnostic odds ratio, and AUC were analyzed. We included 11 articles in our meta-analysis, including 7537 patients who underwent total hip and knee arthroplasties; among these, 1974 (26%) patients reported a joint infection. The pooled sensitivity and specificity were 0.72 and 0.74, respectively, for NLR, 0.72 and 0.77 for PVR, and 0.77 and 0.75 for PLR. The sensitivity of MLR ranges from 0.54 to 0.81, while the specificity ranges from 0.78 to 0.81. Regarding the evaluation of AUCs, the best diagnostic performance was achieved by MLR (AUC = 0.77) followed by PLR (AUC = 0.75), NLR (AUC = 0.73), and PVR (AUC = 0.70). This meta-analysis demonstrates a fair diagnostic accuracy of these ratios, thus not being useful as a screening tool.
A Rare Case of Aphasia Caused by Delayed Epidural Abscess 6 Years after Cranioplasty
Authors: Kim Jae Ho , Kim Dae Kyun , Kim Seok Won
Published: August 2022

Cranioplasty following decompressive craniectomy for severe head trauma or stroke encompasses various cranial reconstruction techniques that use autograft or allograft materials. It not only provides protection and cosmetic benefits to the brain but also facilitates neurological function. One of the most important and undesirable complications of cranioplasty is graft infection, which usually develops within several days to months. Here, we report the case of a 46-year-old man who was admitted with aphasia caused by a delayed epidural abscess 6 years after cranioplasty. The possible pathophysiological mechanisms of this rare entity are discussed along with a review of the relevant literature.
Training Vision Transformers in Federated Learning with Limited Edge-Device Resources
Authors: Tao Jiang , Gao Zhen , Guo Zhaohui
Published: August 2022

Vision transformers (ViTs) demonstrate exceptional performance in numerous computer vision tasks owing to their self-attention modules. Despite improved network performance, transformers frequently require significant computational resources. The increasing need for data privacy has encouraged the development of federated learning (FL). Traditional FL places a computing burden on edge devices. However, ViTs cannot be directly applied through FL on resource-constrained edge devices. To utilize the powerful ViT structure, we reformulated FL as a federated knowledge distillation training algorithm called FedVKD. FedVKD uses an alternating minimization strategy to train small convolutional neural networks on edge nodes and periodically transfers their knowledge to a large server-side transformer encoder via knowledge distillation. FedVKD affords the benefits of reduced edge-computing load and improved performance for vision tasks, while preserving FedGKT-like asynchronous training. We used four datasets and their non-IID variations to test the proposed FedVKD. When utilizing a larger dataset, FedVKD achieved higher accuracy than FedGKT and FedAvg.
Dynamic Impacts of External Uncertainties on the Stability of the Food Supply Chain: Evidence from China
Authors: Li Jingdong , Song Zhouying
Published: August 2022

The food supply chain operates in a complex and dynamic external environment, and the external uncertainties from natural and socio-economic environment pose great challenges to the development of the food industry. In particular, the COVID-19 pandemic and Russia–Ukraine conflict have further exacerbated the vulnerability of the global food supply chain. Analyzing the dynamic impacts of external uncertainties on the stability of food supply chain is central to guaranteeing the sustainable security of food supply. Based on the division of food supply chain and the classification of external uncertainties, the TVP-FAVAR-SV model was constructed to explore the dynamic impacts of external uncertainties on food supply chain. It was found that the impacts of external uncertainty elements were significantly different, the combination of different external uncertainty elements aggravated or reduced the risks of food supply chain. And some uncertainty elements had both positive and negative impacts in the whole sample period, as the magnitude and direction of the impacts of various uncertainties in different periods had time-varying characteristics.
Coffee Leaf Tea from El Salvador: On-Site Production Considering Influences of Processing on Chemical Composition
Authors: Steger Marc C. , Rigling Marina , Blumenthal Patrik , Segatz Valerie , Quintanilla-Belucci Andrès , Beisel Julia M. , Rieke-Zapp Jörg , Schwarz Steffen , Lachenmeier Dirk W. , Zhang Yanyan
Published: August 2022

The production of coffee leaf tea (Coffea arabica) in El Salvador and the influences of processing steps on non-volatile compounds and volatile aroma-active compounds were investigated. The tea was produced according to the process steps of conventional tea (Camellia sinensis) with the available possibilities on the farm. Influencing factors were the leaf type (old, young, yellow, shoots), processing (blending, cutting, rolling, freezing, steaming), drying (sun drying, oven drying, roasting) and fermentation (wild, yeast, Lactobacillus). Subsequently, the samples were analysed for the maximum levels of caffeine, chlorogenic acid, and epigallocatechin gallate permitted by the European Commission. The caffeine content ranged between 0.37–1.33 g/100 g dry mass (DM), the chlorogenic acid was between not detectable and 9.35 g/100 g DM and epigallocatechin gallate could not be detected at all. Furthermore, water content, essential oil, ash content, total polyphenols, total catechins, organic acids, and trigonelline were determined. Gas chromatography—mass spectrometry—olfactometry and calculation of the odour activity values (OAVs) were carried out to determine the main aroma-active compounds, which are β-ionone (honey-like, OAV 132-927), decanal (citrus-like, floral, OAV 14-301), α-ionone (floral, OAV 30-100), (E,Z)-2,6-nonadienal (cucumber-like, OAV 18-256), 2,4-nonadienal (melon-like, OAV 2-18), octanal (fruity, OAV 7-23), (E)-2 nonenal (citrus-like, OAV 1-11), hexanal (grassy, OAV 1-10), and 4-heptenal (green, OAV 1-9). The data obtained in this study may help to adjust process parameters directly to consumer preferences and allow coffee farmers to earn an extra income from this by-product.
A Variational Level Set Image Segmentation Method via Fractional Differentiation
Authors: Liu Xiangguo , Liu Guojun , Wang Yazhen , Li Gengsheng , Zhang Rui , Peng Weicai
Published: August 2022

To solve the issues with conventional level set segmentation algorithms, which are sensitive to the initial contours and less noise-resistant, a segmentation model based on the coupling of texture information and structural information is developed. In this model, a rotation invariant mask produced by fractional-order differentiation is used to first describe the image’s global information. Then, the power function of the energy generalization function is solved by applying factorization theory, and for each pixel of the image, not only its information but also its surrounding pixel information is taken into account and integrated into the energy generalization function via weight scaling. At the same time, the L2 norm of the fractional-order image and the difference from the fitted image are used to generate the energy generalization function of the model. The final results of this study demonstrate that the proposed model achieved a better segmentation performance than the current active contour models in terms of robustness to Gaussian noise and pretzel noise, as well as the segmentation accuracy and algorithm running time. These results were obtained in synthetic images, real images, and natural images.
Development of Eco-Friendly Hydrophobic and Fouling-Release Coatings for Blue-Growth Environmental Applications: Synthesis, Mechanical Characterization and Biological Activity
Authors: Sfameni Silvia , Rando Giulia , Marchetta Alessia , Scolaro Cristina , Cappello Simone , Urzì Clara , Visco Annamaria , Plutino Maria Rosaria
Published: August 2022

The need to ensure adequate antifouling protection of the hull in the naval sector led to the development of real painting cycles, which involve the spreading of three layers of polymeric material on the hull surface exposed to the marine environment, specifically defined as primer, tie coat and final topcoat. It is already well known that coatings based on suitable silanes provide an efficient and non-toxic approach for the hydrophobic and antifouling/fouling release treatment of surfaces. In the present work, functional hydrophobic hybrid silica-based coatings (topcoats) were developed by using sol-gel technology and deposited on surfaces with the “doctor blade” method. In particular, those organic silanes, featuring opportune functional groups such as long (either fluorinated) alkyl chains, have a notable influence on surface wettability as showed in this study. Furthermore, the hydrophobic behavior of this functionalized coating was improved by introducing an intermediate commercial tie-coat layer between the primer and the topcoat, in order to decrease the wettability (i.e., decreasing the surface energy with a matching increase in the contact angle, CA) and to therefore make such coatings ideal for the design and development of fouling release paints. The hereby synthesized coatings were characterized by optical microscopy, contact angle analysis and a mechanical pull-off test to measure the adhesive power of the coating against a metal substrate typically used in the nautical sector. Analysis to evaluate the bacterial adhesion and the formation of microbial biofilm were related in laboratory and simulation (microcosm) scales, and assessed by SEM analysis.
Simple Sequence Repeat Markers Reveal Genetic Diversity and Population Structure of Bolivian Wild and Cultivated Tomatoes (Solanum lycopersicum L.)
Authors: Villanueva-Gutierrez Evelyn E. , Johansson Eva , Prieto-Linde Maria Luisa , Centellas Quezada Alberto , Olsson Marie E. , Geleta Mulatu
Published: August 2022

The western part of South America is a centre of diversity for tomatoes, but genetic diversity studies are lacking for parts of that region, including Bolivia. We used 11 simple sequence repeat (SSR) markers (including seven novel markers) to evaluate genetic diversity and population structure of 28 accessions (four modern cultivars, four advanced lines, nine landraces, 11 wild populations), and to compare their genetic variation against phenotypic traits, geographical origin and altitude. In total, 33 alleles were detected across all loci, with 2–5 alleles per locus. The top three informative SSRs were SLM6-11, LE20592 and TomSatX11-1, with polymorphism information content (PIC) of 0.65, 0.55 and 0.49, respectively. The genetic diversity of Bolivian tomatoes was low, as shown by mean expected heterozygosity (He) of 0.07. Analysis of molecular variance (AMOVA) revealed that 77.3% of the total variation was due to variation between accessions. Significant genetic differentiation was found for geographical origin, cultivation status, fruit shape, fruit size and growth type, each explaining 16–23% of the total variation. Unweighted Pair Group Method with Arithmetic Mean (UPGMA) tree and principal coordinate analysis (PCoA) scatter plot both revealed differentiation between accessions with determinate flowers and accessions with indeterminate flowers, regardless of cultivation status. The genetic profiles of the accessions suggest that the Bolivian tomato gene pool comprises both strictly self-pollinating and open-pollinating genotypes.
SPACR Encoded by IMPG1 Is Essential for Photoreceptor Survival by Interplaying between the Interphotoreceptor Matrix and the Retinal Pigment Epithelium
Authors: Olivier Guillaume , Brabet Philippe , Pirot Nelly , Broyon Morgane , Guillou Laurent , Cazevieille Chantal , Sar Chamroeun , Quiles Melanie , Sarzi Emmanuelle , Pequignot Marie , Andreo Ervann , Roubertie Agathe , Meunier Isabelle , Muller Agnès , Kalatzis Vasiliki , Manes Gaël
Published: August 2022

Several pathogenic variants have been reported in the IMPG1 gene associated with the inherited retinal disorders vitelliform macular dystrophy (VMD) and retinitis pigmentosa (RP). IMPG1 and its paralog IMPG2 encode for two proteoglycans, SPACR and SPACRCAN, respectively, which are the main components of the interphotoreceptor matrix (IPM), the extracellular matrix surrounding the photoreceptor cells. To determine the role of SPACR in the pathological mechanisms leading to RP and VMD, we generated a knockout mouse model lacking Impg1, the mouse ortholog. Impg1-deficient mice show abnormal accumulation of autofluorescent deposits visible by fundus imaging and spectral-domain optical coherence tomography (SD-OCT) and attenuated electroretinogram responses from 9 months of age. Furthermore, SD-OCT of Impg1−/− mice shows a degeneration of the photoreceptor layer, and transmission electron microscopy shows a disruption of the IPM and the retinal pigment epithelial cells. The decrease in the concentration of the chromophore 11-cis-retinal supports this loss of photoreceptors. In conclusion, our results demonstrate the essential role of SPACR in maintaining photoreceptors. Impg1−/− mice provide a novel model for mechanistic investigations and the development of therapies for VMD and RP caused by IMPG1 pathogenic variants.
Japanese Flounder HMGB1: A DAMP Molecule That Promotes Antimicrobial Immunity by Interacting with Immune Cells and Bacterial Pathogen
Authors: Chen Yuan , Yu Chao , Jiang Shuai , Sun Li
Published: August 2022

High mobility group box (HMGB) proteins are DNA-associated proteins that bind and modulate chromosome structures. In mammals, HMGB proteins can be released from the cell nucleus and serve as a damage-associated molecular pattern (DAMP) under stress conditions. In fish, the DAMP function of HMGB proteins in association with bacterial infection remains to be investigated. In this study, we examined the immunological functions of two HMGB members, HMGB1 and HMG20A, of Japanese flounder. HMGB1 and HMG20A were expressed in multiple tissues of the flounder. HMGB1 was released from peripheral blood leukocytes (PBLs) upon bacterial challenge in a temporal manner similar to that of lactate dehydrogenase release. Recombinant HMGB1 bound to PBLs and induced ROS production and the expression of inflammatory genes. HMGB1 as well as HMG20A also bound to various bacterial pathogens and caused bacterial agglutination. The bacteria-binding patterns of HMGB1 and HMG20A were similar, and the binding of HMGB1 competed with the binding of HMG20A but not vice versa. During bacterial infection, HMGB1 enhanced the immune response of PBLs and repressed bacterial invasion. Collectively, our results indicate that flounder HMGB1 plays an important role in antimicrobial immunity by acting both as a modulator of immune cells and as a pathogen-interacting DAMP.
Genome-Wide Association Study Identifies Candidate Genes for Stripe Pattern Feather Color of Rhode Island Red Chicks
Authors: Shen Qingmiao , Zhou Jieke , Li Junying , Zhao Xiaoyu , Zheng Lijie , Bao Haigang , Wu Changxin
Published: August 2022

Feather colors of chickens are not only characteristics of breeds but also as phenotypic markers in chicken breeding. Pure-bred Rhode Island Red (RIR) chicks have a stripe pattern and a non-stripe pattern on the back. The stripe pattern of RIR is generally shown as four longitudinal black stripes on the back and is more likely to appear in females. In this study, we performed a genome-wide association study (GWAS) to identify candidate genes controlling the stripe pattern of RIR chicks, and then, based on physical location and biological functions, quantitative RT-PCR analysis was used to validate the differential expression of candidate genes between stripe pattern and non-stripe pattern back skin tissue. The GWAS showed that a major signal contains 768 significant single nucleotide polymorphisms (SNPs) and 87 significant small insertions-deletions (INDELs) spanning 41.78 to 43.05 Mb (~1.27 Mb) on GGA1, corresponding to 16 genes associated with stripe pattern phenotype. Among these 16 genes, KITLG and TMTC3 could be considered candidate genes as they showed different expressions between back skin tissues of stripe pattern and non-stripe pattern chicks in value (p = 0.062) and the significant level (p < 0.05), respectively. This study provided novel insight into the mechanisms underlying feather pigmentation and stripe formation in RIR chicks.
Making Sure That Orphan Incentives Tip the Right Way in Europe
Authors: Horgan Denis , Koeva-Balabanova Jasmina , Capoluongo Ettore , Jagielska Beata , Cattaneo Ivana , Kozaric Marta , Tumiene Birute , El Ahl Jean-Paul , Lal Jonathan A. , Kalra Dipak , Malats Núria
Published: August 2022

The delicate balance of funding research and development of treatments for rare disease is only imperfectly achieved in Europe, and even the current provisional equilibrium is under a new threat from well-intentioned policy changes now in prospect that could—in addition to the intrinsic complexities of research—reduce the incentives on which commercial activity in this area is dependent. The European Union review of its pharmaceutical legislation, for which proposals are scheduled to appear before the end of 2022, envisages adjusting the decade-old incentives to meet objectives that are more precisely targeted. However, researchers, physicians, patients and industry have expressed concerns that ill-considered modifications could have unintended consequences in disrupting the current balance and could reduce rather than increase the flow of innovative treatments for rare diseases.
Soil Nutrient Status and Morphometric Responses of Guava under Drip Irrigation and High-Tech Horticultural Techniques for Sustainable Farming
Authors: Preet Manpreet Singh , Kumar Rajesh , Valipour Mohammad , Singh Vijay Pratap , Neha  , Singh Ashok Kumar , Iqbal Rashid , Zafar Muhammad Umar , Sharma Rashmi , Singh Shiv Vendra , Kumari Arpna , Minkina Tatiana , Soufan Walid , Faraj Turki Kh. , Ditta Allah , Sabagh Ayman El
Published: August 2022

In the current study, efforts were made to standardize fertigation for providing the recommended doses of fertilizers (RDF) i.e., 300, 260, and 200 g/plant/year for N, P, and K, respectively, together with optimization of irrigation scheduling so that guava plants could avoid the frequent episodes of nutritional stress, water scarcity, or overwatering. The experiment’s execution was confined to a three-factor randomized block design, with a total of 19 treatments that were replicated four times. Briefly, these treatments included drip irrigation and nutrient (NPK) application through fertigation dosages (RDF; 100, 80, and 60%) with and without silver-black plastic mulching. Different applied fertilizer dosages, together with different levels of irrigation and soil mulching, had a significant impact on the guava plant’s vegetative, reproductive, and nutritional aspects. Under silver-black plastic mulch, drip irrigation at cumulative pan evaporation (CPE) 80 and 100% of the prescribed dosage of fertilizers, better macronutrient availability in the soil, and improved plant development were recorded (M1DI2F1). Overall, using drip fertigation to provide NPK fertilizers close to the root zone increased the availability of nutrients to the plants as compared to the traditional fertigation and irrigation methods. Thus, this sustainable high-tech horticultural approach could be analyzed for its efficacy or applied to other crops to obtain adequate economic outcomes.
Quantitative Assessment of First Nations Drinking Water Distribution Systems for Detection and Prevalence of Thermophilic Campylobacter Species
Authors: Khan Izhar U. H. , Murdock Anita , Mahmud Maria , Cloutier Michel , Benoit Thomas , Bashar Sabrin , Patidar Rakesh , Mi Ruidong , Daneshfar Bahram , Farenhorst Annemieke , Kumar Ayush
Published: August 2022

Water is considered a major route for transmitting human-associated pathogens. Although microbial water quality indicators are used to test for the presence of waterborne pathogens in drinking water, the two are poorly correlated. The current study investigates the prevalence of thermophilic DNA markers specific for Campylobacter spp. (C. jejuni and C. coli) in source water and throughout the water distribution systems of two First Nations communities in Manitoba, Canada. A total of 220 water samples were collected from various points of the drinking water distribution system (DWDS) between 2016 and 2018. Target Campylobacter spp. were always (100%) detected in a home with a fiberglass (CF) cistern, as well as the community standpipe (SP). The target bacteria were also frequently detected in treated water at the Water Treatment Plant (WTP) (78%), homes with polyethylene (CP) (60%) and concrete (CC) (58%) cisterns, homes with piped (P) water (43%) and water truck (T) samples (20%), with a maximum concentration of 1.9 × 103 cells 100 mL−1 (C. jejuni) and 5.6 × 105 cells 100 mL−1 (C. coli). Similarly, target bacteria were detected in 68% of the source water samples with a maximum concentration of 4.9 × 103 cells 100 mL−1 (C. jejuni) and 8.4 × 105 cells 100 mL−1 (C. coli). Neither target Campylobacter spp. was significantly associated with free and total chlorine concentrations in water. The study results indicate that there is an immediate need to monitor Campylobacter spp. in small communities of Canada and, particularly, to improve the DWDS in First Nations communities to minimize the risk of Campylobacter infection from drinking water sources. Further research is warranted in improving/developing processes and technologies to eliminate microbial contaminants from water.
Effect of Coronavirus 19 on Maintaining Balance in Skilled Athletes
Authors: Jaszczur-Nowicki Jarosław , Niźnikowski Tomasz , Makaruk Hubert , Mastalerz Andrzej , Porter Jared , Biegajło Michał , Niźnikowska Ewelina , Markwell Logan , Nogal Marta , Łuba-Arnista Weronika , Arnista Paweł , Romero-Ramos Oscar
Published: August 2022

Preliminary studies have reported that motor control is negatively impacted following an infection of COVID-19. The purpose of this study was to evaluate the effect of COVID-19 on maintaining balance in highly skilled athletes. As part of a larger investigation that was initiated in 2019, twelve professional handball players were recruited to participate in a study that was designed to measure static balance performance. Following the initial pre-test, six participants (body height 184.8 ± 4.7 cm; body weight 85.5 ± 3.3 kg; age 21.3 ± 1.2 years) were infected with COVID-19. The remaining six participants (body height 188.7 ± 2.6 cm; body weight 92.3 ± 3.7 kg; age 26.3 ± 3.3 years) never tested positive for COVID-19 and were presumably not infected with the virus. The experimental design required all the participants to complete an initial balance assessment (pre-test) and a later balance assessment (post-test). To fully analyze our data, we conducted a 2 (condition: COVID, no-COVID) X 2 (test: pre-test, post-test) ANOVA with repeated measures on the second factor. Our analysis revealed that the skilled athletes who contracted COVID-19 had a significant decrease in balance performance from the pre-test that occurred prior to being infected with COVID-19 relative to the post-test that occurred following the COVID-19 infection. Additionally, the skilled athletes who were not infected with COVID-19 did not demonstrate the same deterioration in balance performance in the same period. This study highlights the impact COVID-19 has on static balance performance in a group of highly skilled handball players. Longitudinal studies are needed to fully understand the lasting impacts COVID-19 has on motor behavior.
Lifestyle Factors Associated with Metabolic Syndrome in Urban Cambodia
Authors: Tamaoki Miharu , Honda Ikumi , Nakanishi Keisuke , Nakajima Maki , Cheam Sophathya , Okawada Manabu , Sakakibara Hisataka
Published: August 2022

This study aimed to identify lifestyle factors associated with metabolic syndrome (MetS) in urban Cambodia. In this cross-sectional study, we used existing health checkup data from a private hospital in Phnom Penh, Cambodia. The participants comprised 5459 Cambodians aged ≥20 years who underwent health checkups between 2017 and 2019. The harmonized diagnostic definition was used as the MetS criteria. The prevalence of MetS was 56.6% overall, 60.4% in men and 52.6% in women. The lifestyle factor significantly associated with MetS in both sexes were “eating quicker than others”, (men: odds ratio [OR]= 2.25, 95% confidence interval [CI] = 1.68–3.03, women: OR = 1.92, 95%CI = 1.41–2.60), “walking faster than others”, (men: OR = 0.78, 95% CI = 0.67–0.92, women: OR = 0.75, 95% CI = 0.62–0.89) and “drinking alcohol” (men: OR = 1.33, 95% CI = 1.10–1.61, women: OR = 1.33, 95% CI = 1.09–1.62). Other significant associations with MetS for men was “eating speed is normal”, (OR = 1.73, 95%CI = 1.30–2.31), and, for women, “eating food after dinner at least 3 days a week”, (OR = 1.25, 95%CI = 1.01–1.55), “skipping breakfast at least 3 days a week”, (OR = 0.83, 95%CI = 0.69–0.99) and “getting enough rest from sleep” (OR = 1.19, 95% CI = 1.01–1.42) were significantly associated with MetS. Lifestyle interventions through health education and guidance may be effective in preventing MetS in Cambodia.
Fetal Exposure to Air Pollution in Late Pregnancy Significantly Increases ADHD-Risk Behavior in Early Childhood
Authors: Liu Binquan , Fang Xinyu , Strodl Esben , He Guanhao , Ruan Zengliang , Wang Ximeng , Liu Li , Chen Weiqing
Published: August 2022

Background: Air pollution nowadays has seriously threatened the health of the Chinese population, especially in the vulnerable groups of fetuses, infants and toddlers. In particular, the effects of air pollution on children’s neurobehavioral development have attracted widespread attention. Moreover, the early detection of a sensitive period is very important for the precise intervention of the disease. However, such studies focusing on hyperactive behaviors and susceptible window identification are currently lacking in China. Objectives: The study aims to explore the correlation between air pollution exposure and hyperactive behaviors during the early life stage and attempt to identify whether a susceptible exposure window exists that is crucial for further precise intervention. Methods: Based on the Longhua Child Cohort Study, we collected the basic information and hyperactivity index of 26,052 children using a questionnaire conducted from 2015 to 2017, and the Conners’ Parent Rating Scale-revised (CPRS-48) was used to assess hyperactive behaviors. Moreover, the data of air pollution concentration (PM10, PM2.5, NO2, CO, O3 and SO2) were collected from the monitoring station between 2011 to 2017, and a land-use random forest model was used to evaluate the exposure level of each subject. Furthermore, Distributed lag non-linear models (DLNMs) were applied for statistic analysis. Results: The risk of child hyperactivity was found to be positively associated with early life exposure to PM10, PM2.5 and NO2. In particular, for an increase of per 10 µg/m3 in PM10, PM2.5 and NO2 exposure concentration during early life, the risk of child hyperactivity increased significantly during the seventh month of pregnancy to the fourth month after birth, with the strongest association in the ninth month of pregnancy (PM10: OR = 1.043, 95% CI: 1.016–1.071; PM2.5: OR = 1.062, 95% CI: 1.024–1.102; NO2: OR = 1.043, 95% CI: 1.016–1.071). However, no significant associations among early life exposure to CO, O3 and SO2 and child hyperactive behaviors were observed. Conclusions: Early life exposure to PM10, PM2.5 and NO2 is associated with an increased risk of child ADHD-like behaviors at the age around 3 years, and the late-prenatal and early postnatal periods might be the susceptible exposure windows.
Factors Related to Oversleeping in Korean Young Adults, with a Focus on Sociodemographic Factors
Authors: Noh Jin-Won , Kim Jinseok , Lee Yejin , Kwon Young Dae
Published: August 2022

Young adults the year after high school experience changes in lifestyle and circumstances and tend to experience more oversleeping. However, there are few studies on oversleeping in young adults. This study aims to identify the sociodemographic factors related to oversleeping among young adults in Korea using nationally representative data. This study analyzed self-reported and cross-sectional data in 2016 from a sample of 1876 participants from the Korean Children and Youth Panel Survey, which included respondents one year after high school graduation. Oversleeping was defined as sleeping 9 or more hours a day on average. Logistic regression models were analyzed to test a multivariate association between independent sociodemographic variables and oversleeping. Over one-tenth of young adults reported oversleeping. Oversleeping was associated with household income (OR = 0.99, p = 0.011) and smoking (OR = 1.52, p = 0.041). In addition, when compared to non-working college students, college students who were working (OR = 2.58, p = 0.021), non-students who were working (OR = 1.68, p = 0.048), and non-students who were not working (OR = 3.07, p < 0.001) were more likely to report oversleeping. Oversleeping among young adults was associated with major sociodemographic factors including household income (−), smoking (+), and academic and working status (+). These findings suggest the significant role of sociodemographic factors as predictors of oversleeping and emphasize the importance of examining various factors to achieve a better understanding of oversleeping in young adults.
A Simple Resident Need-for-Physical-Assistance Scale in Eldercare: Validation Using 4716 Observation Sequences of Caring Activities
Authors: Jacobsen Sandra Schade , Stevens Matthew Leigh , Karstad Kristina , Rasmussen Charlotte Diana Nørregaard , Kühnel Alexander Bork , Holtermann Andreas
Published: August 2022

Accurate and simple measures for classifying nursing home residents according to their care needs would be valuable for planning eldercare work. Our aim was to validate a developed classification scale of residents’ need for physical assistance. Eldercare workers and managers in 20 Danish nursing homes classified 1456 residents into four categories (from light to complete need for physical assistance). We validated the resident need-for-assistance scale against 4716 workplace observation sequences of caring activities performed by eldercare workers. We found a strong correlation between the resident need-for-assistance scale and observed number of resident handlings (r = 0.71) and a moderate correlation for observed duration of care (r = 0.57). The discriminative ability of the scale was good for both number of resident handlings (ROC-AUC = 0.81) and for duration of care (ROC-AUC = 0.76). Our findings indicate that this simple scale is valid and feasible for classifying residents according to their physical assistance needs.
Associations between Muscle Strength, Physical Performance and Cognitive Impairment with Fear of Falling among Older Adults Aged ≥ 60 Years: A Cross-Sectional Study
Authors: Orihuela-Espejo Antonio , Álvarez-Salvago Francisco , Martínez-Amat Antonio , Boquete-Pumar Carmen , De Diego-Moreno Manuel , García-Sillero Manuel , Aibar-Almazán Agustín , Jiménez-García José Daniel
Published: August 2022

(1) Background: Fear of falling has become a significant health problem in older adults and is already considered as important as falling because of its long-term detrimental effects on older adults’ physical and psychosocial functioning. The aim of this study was to analyze the associations between both upper and lower limb strength, gait parameters and cognitive impairment with fear of falling in older adults. (2) Methods: A cross-sectional study involving 115 older-adult participants was used to assess the impact of both upper (Handgrip dynamometer, TKK 5401 Grip-D, Takey, Tokyo, Japan) and lower limb strength (Chair stand test), gait parameters (OptoGait-System Bolzano, Bolzano, Italy) and cognitive impairment (COWAT word association test) with fear of falling in older adults (Falls Efficacy Scale-International FES-I). (3) Results: Multivariate linear regression analysis showed several independent associations with the fear of falling. A higher time to perform the Chair Stand test was associated with higher scores in FES-I (R2 = 0.231), while a lower score in both Semantic Fluency (S COWA) and Phonologic Fluency (P COWA) was associated with a decreased score in FES-I (R2 = 0.052 and 0.035). (4) Conclusions: Both higher step and stride length (OptoGait), lower body strength (Chair test) and both poorer semantic (S COWA) and phonologic (P COWA) fluency were all associated with fear of falling.
Early Prediction of At-Risk Students in Secondary Education: A Countrywide K-12 Learning Analytics Initiative in Uruguay
Authors: Queiroga Emanuel Marques , Batista Machado Matheus Francisco , Paragarino Virgínia Rodés , Primo Tiago Thompsen , Cechinel Cristian
Published: August 2022

This paper describes a nationwide learning analytics initiative in Uruguay focused on the future implementation of governmental policies to mitigate student retention and dropouts in secondary education. For this, data from a total of 258,440 students were used to generate automated models to predict students at risk of failure or dropping out. Data were collected from primary and secondary education from different sources and for the period between 2015 and 2020. Such data contains demographic information about the students and their trajectories from the first grade of primary school to the second grade of secondary school (e.g., student assessments in different subjects over the years, the amount of absences, participation in social welfare programs, and the zone of the school, among other factors). Predictive models using the random forest algorithm were trained, and their performances were evaluated with F1-Macro and AUROC measures. The models were planned to be applied in different periods of the school year for the regular secondary school and for the technical secondary school ((before the beginning of the school year and after the first evaluation meeting for each grade). A total of eight predictive models were developed considering this temporal approach, and after an analysis of bias considering three protected attributes (gender, school zone, and social welfare program participation), seven of them were approved to be used for prediction. The models achieved outstanding performances according to the literature, with an AUROC higher than 0.90 and F1-Macro higher than 0.88. This paper describes in depth the characteristics of the data gathered, the specifics of data preprocessing, and the methodology followed for model generation and bias analysis, together with the architecture developed for the deployment of the predictive models. Among other findings, the results of the paper corroborate the importance given in the literature of using the previous performances of the students in order to predict their future performances.
Effectiveness of Bubble Continuous Positive Airway Pressure (BCPAP) for Treatment of Children Aged 1–59 Months with Severe Pneumonia and Hypoxemia in Ethiopia: A Pragmatic Cluster Randomized Controlled Clinical Trial
Authors: Gebre Meseret , Haile Kassa , Duke Trevor , Faruk Md. Tanveer , Kamal Mehnaz , Kabir Md Farhad , Uddin Md. Fakhar , Shimelis Muluye , Solomon Bethelhem , Bayih Abebe Genetu , Abdissa Alemseged , Balcha Taye Tolera , Argaw Rahel , Demtse Asrat , Yeshidenber Abate , Girma Abayneh , Haile Bitseat W. , Ahmed Tahmeed , Clemens John D. , Chisti Mohammod Jobayer
Published: August 2022

Despite the beneficial effect of bubble continuous positive airway pressure (BCPAP) oxygen therapy for children with severe pneumonia under the supervision of physicians that has been shown in different studies, effectiveness trials in developing country settings where low-flow oxygen therapy is the standard of care are still needed. Thus, the aim of this study is to assess the effectiveness of bubble CPAP oxygen therapy compared to the WHO standard low-flow oxygen therapy among children hospitalized with severe pneumonia and hypoxemia in Ethiopia. This is a cluster randomized controlled trial where six district hospitals are randomized to BCPAP and six to standard WHO low-flow oxygen therapy. The total sample size is 620 per arm. Currently, recruitment of the patients is still ongoing where the management and follow-up of the enrolled patients are performed by general physicians and nurses under the supervision of pediatricians. The primary outcome is treatment failure and main secondary outcome is death. We anticipate to complete enrollment by September 2022 and data analysis followed by manuscript writing by December 2022. Findings will also be disseminated in December 2022. Our study will provide data on the effectiveness of BCPAP in treating childhood severe pneumonia and hypoxemia in a real-world setting.
Effects of SARS-CoV-2 Infection on Pulmonary Function Tests and Exercise Tolerance
Authors: Ora Josuel , Zerillo Bartolomeo , De Marco Patrizia , Manzetti Gian , De Guido Ilaria , Calzetta Luigino , Rogliani Paola
Published: August 2022

Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been shown to cause long-term pulmonary sequelae. Objects: The aim of this study was to evaluate the consequences of the SARS-CoV-2 infection on pulmonary function and on the 6-min walk test related to the severity of the disease. Methods: A cross-sectional study was conducted at the “Policlinico Tor Vergata” Academic Hospital (Rome, Italy), including 75 patients evaluated in post-COVID clinics at the Respiratory Units between November 2020 and September 2021. Complete pulmonary function tests, 6-min walk tests and persistence of symptoms were performed. Results: Of the 75 subjects, 23 had mild, 16 moderate, 26 severe and 10 very severe COVID-19, classified according to WHO. Very severe patients had a lower FVC (100 ± 10%pr) compared to the other groups (116 ± 16%pr, 116 ± 13%pr, 122 ± 20%pr from mild to severe; p < 0.05) and a lower TLC (94 ± 13%pr) compared to the others (102 ± 10%pr, 108 ± 15%pr, 108 ± 12%pr from mild to severe; p < 0.05). DLco and DLco/VA were similar among groups. At the 6MWT, distance, rest and nadir SpO2 were similar among groups, but all groups presented a significant decrease in SpO2 from rest to nadir (Rest SpO2: 97.0 ± 1.0% vs. Nadir SpO2: 93.6 ± 2.7%, p < 0.01). A positive correlation was found between desaturation and delta SpO2 (rest—nadir) (R: 0.29, p < 0.05) and the Distance Desaturation Product (R: 0.39, p < 0.01). Conclusions: These results showed that, although the PFTs are within the normal range, there is still a mild restrictive spirometric pattern after six months in very severe subjects. Moreover, the only persistent pathological sequalae of SARS-CoV-2 infection were a mild desaturation at 6MWT, despite the severity of the infection.