bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of Corrosion Mechanisms in Corrosive Media and Their Influence on the Absorption Capacity of Fe2O3/NdFeO3 Nanocomposites
Authors: Kadyrzhanov Kayrat K. , Kozlovskiy Artem L. , Egizbek Kamila , Kenzhina Inesh E. , Abdinov Rauan Sh. , Zdorovets Maxim V.
Published: July 2022

This paper presents the results of a study of the change in the stability of Fe2O3/NdFeO3 nanocomposites when exposed to aggressive media over a long period of time. The main purpose of these studies is to investigate the mechanisms of degradation and corrosion processes occurring in Fe2O3/NdFeO3 nanocomposites, as well as the influence of the phase composition on the properties and degradation resistance. According to the X-ray phase analysis, it was found that the variation of the initial components leads to the formation of mixed composition nanocomposites with different Fe2O3/NdFeO3 phase ratios. During corrosion tests, it was found that the dominance of the NdFeO3 phase in the composition of nanocomposites leads to a decrease in the degradation and amorphization rate of nanostructures by a factor of 1.5–2 compared to structures in which the Fe2O3 phase dominates. Such a difference in the degradation processes indicates the high stability of two-phase composites. Moreover, in the case of an aqueous medium, nanocomposites dominated by the NdFeO3 phase are practically not subjected to corrosion and deterioration of properties. The results obtained helped to determine the resistance of Fe2O3/NdFeO3 nanocomposites to degradation processes caused by exposure to aggressive media, as well as to determine the mechanisms of property changes in the process of degradation. The results of the study of the absorption capacity of Fe2O3/NdFeO3 nanocomposites in the case of the purification of aqueous media from manganese and arsenic showed that a change in the phase ratio in nanocomposites leads to an increase in the absorption efficiency of pollutants from aqueous media.
Nanoencapsulation of Eggplant (Solanum melongena L.) Peel Extract in Electrospun Gelatin Nanofiber: Preparation, Characterization, and In Vitro Release
Authors: Estrella-Osuna Danya Elizabeth , Tapia-Hernández José Agustín , Ruíz-Cruz Saúl , Márquez-Ríos Enrique , Ornelas-Paz José de Jesús , Del-Toro-Sánchez Carmen Lizette , Ocaño-Higuera Víctor Manuel , Rodríguez-Félix Francisco , Estrada-Alvarado María Isabel , Cira-Chávez Luis Alberto
Published: July 2022

This study describes the preparation and characterization of eggplant peel extract-loaded electrospun gelatin nanofiber and study of its in vitro release. Results obtained by scanning electron microscopy (SEM) and transmission electronic microscopy (TEM) micrograph revealed that eggplant peel extract-loaded electrospun gelatin nanofiber is in nanometric range with an average diameter 606.7 ± 184.5 and 643.6 ± 186.7 nm for 20 and 33.3 mg mL−1 of extract addition, respectively. Moreover, the incorporation of extract improved morphology by being smooth, homogeneous, and without account formation compared to nanofibers without extract (control). Fourier transform-infrared (FT-IR) spectra indicated that interaction exists between electrospun gelatin nanofiber and eggplant peel extract by hydrogen bond interactions, mainly. Electrospun gelatin nanofibers showed encapsulation efficiency greater than 90% of extract and a maximum release of 95 and 80% for the medium at pH 1.5 and 7.5, respectively. Therefore, the electrospinning technique is a good alternative for the conservation of bioactive compounds present in the eggplant peel through electrospun gelatin nanofiber.
Burnout and Nursing Care: A Concept Paper
Authors: Parola Vitor , Coelho Adriana , Neves Hugo , Bernardes Rafael A. , Sousa Joana Pereira , Catela Nuno
Published: July 2022

Burnout comprises a series of undetermined physical and psychosocial symptoms caused by an excessive energy requirement at work—it is a crisis in relationships with work itself and not necessarily a concern with underlying clinical disorders related to workers. Professions involving human interactions commonly involve emotional engagement, especially when the cared-for person needs assistance and support, as is the primary concern in the nursing profession. To some extent, the acknowledgment of the phenomena of burnout and how it affects people is sometimes addressed from a biomedical perspective. This concept paper aims to describe the burnout concept and reflect on the impact on nurses. Our intention with this reflection, considering the burnout impact on nurses, is to support a paradigm change in the prevention and management of burnout in healthcare contexts, promoting and fostering the well-being of nurses.
Emergency Room Nurses’ Experiences in Person-Centred Care
Authors: Kim Jang Mi , Kim Na Geong , Lee Eun Nam
Published: July 2022

Implementing person-centred care is often considered difficult in congested emergency rooms. The purpose of this study was to understand person-centred care experienced by emergency room nurses in depth and examine the essence of emergency room nurses’ lived experience of the person- centred care. Eight nurses working in the emergency room of a large hospital in South Korea and who had over six months of experience were surveyed via semi-structured interviews in February 2019. The data were transcribed and analysed using Colaizzi’s framework. The major findings related to person-centred care experiences among emergency room nurses were: (1) feeling distanced from patients; (2) guilt and frustration; (3) accepting patients’ symptoms and emotions as they are; (4) person-centred care as a domain of nursing that cannot be replaced by machines; and (5) nursing as an art wherein the minutest details make a difference. Providing person-centred practice in the emergency room is difficult, but it will not only improve the quality of patient care but also increase the job satisfaction of nurses. Based on an in-depth understanding of person-centred care experienced by emergency nurses, it will contribute to enhancing the quality of nursing care in the emergency room.
Integrated Metabolomic and Transcriptomic Analysis of Acute Kidney Injury Caused by Leptospira Infection
Authors: Chen Kuan-Hsing , Chou Li-Fang , Hung Cheng-Chieh , Tang Hsiang-Yu , Cheng Mei-Ling , Yang Huang-Yu , Hsu Hsiang-Hao , Tian Ya-Chung , Yang Chih-Wei
Published: July 2022

Renal leptospirosis caused by leptospiral infection is characterised by tubulointerstitial nephritis and tubular dysfunction, resulting in acute and chronic kidney injury. Metabolomic and transcriptomic data from a murine model of Leptospira infection were analysed to determine whether metabolomic data from urine were associated with transcriptome changes relevant to kidney injury caused by Leptospira infection. Our findings revealed that 37 metabolites from the urine of L. interrogans-infected mice had significantly different concentrations than L. biflexa-infected and non-infected control mice. Of these, urinary L-carnitine and acetyl-L-carnitine levels were remarkably elevated in L. interrogans-infected mice. Using an integrated pathway analysis, we found that L-carnitine and acetyl-L-carnitine were involved in metabolic pathways such as fatty acid activation, the mitochondrial L-carnitine shuttle pathway, and triacylglycerol biosynthesis that were enriched in the renal tissues of the L. interrogans-infected mice. This study highlights that L-carnitine and acetyl-L-carnitine are implicated in leptospiral infection-induced kidney injury, suggesting their potential as metabolic modulators.
Adaptation and Diagnostic Potential of a Commercial Cat Interferon Gamma Release Assay for the Detection of Mycobacterium bovis Infection in African Lions (Panthera leo)
Authors: Gumbo Rachiel , Sylvester Tashnica T. , Goosen Wynand J. , Buss Peter E. , de Klerk-Lorist Lin-Mari , van Schalkwyk O. Louis , McCall Alicia , Warren Robin M. , van Helden Paul D. , Miller Michele A. , Kerr Tanya J.
Published: July 2022

Mycobacterium bovis (M. bovis) infection in wildlife, including lions (Panthera leo), has implications for individual and population health. Tools for the detection of infected lions are needed for diagnosis and disease surveillance. This study aimed to evaluate the Mabtech Cat interferon gamma (IFN-γ) ELISABasic kit for detection of native lion IFN-γ in whole blood samples stimulated using the QuantiFERON® TB Gold Plus (QFT) platform as a potential diagnostic assay. The ELISA was able to detect lion IFN-γ in mitogen-stimulated samples, with good parallelism, linearity, and a working range of 15.6–500 pg/mL. Minimal matrix interference was observed in the recovery of domestic cat rIFN-γ in lion plasma. Both intra- and inter-assay reproducibility had a coefficient of variation less than 10%, while the limit of detection and quantification were 7.8 pg/mL and 31.2 pg/mL, respectively. The diagnostic performance of the QFT Mabtech Cat interferon gamma release assay (IGRA) was determined using mycobacterial antigen-stimulated samples from M. bovis culture-confirmed infected (n = 8) and uninfected (n = 4) lions. A lion-specific cut-off value (33 pg/mL) was calculated, and the sensitivity and specificity were determined to be 87.5% and 100%, respectively. Although additional samples should be tested, the QFT Mabtech Cat IGRA could identify M. bovis-infected African lions.
Reply to Muntean et al. Comment on “Mitteregger et al. A Variant Carbapenem Inactivation Method (CIM) for Acinetobacter baumannii Group with Shortened Time-to-Result: rCIM-A. Pathogens 2022, 11, 482”
Authors: Mitteregger Dieter , Wessely Julian , Barišić Ivan , Bedenić Branka , Kosak Dieter , Kundi Michael
Published: July 2022

We appreciate the interest in our publication and agree that a different acronym for the method would have been better [...]
Diabolical Diagramming: Deleuze, Dupuy, and Catastrophe
Authors: Shores Corry
Published: July 2022

Jean-Pierre Dupuy argues that our failure to prevent the looming climate catastrophe results from a faulty metaphysics of time: because we believe the present can proceed down one of the many branches that extend into the future, some of which bypass the catastrophe, we do not think it is absolutely urgent to take drastic action now. His solution to this problem of demotivation is “enlightened doomsaying” in “projected time”, which means that we affirm the coming catastrophe as something real in the future rather than being a mere possibility; thus, we regard it seriously enough that we are motivated to take the needed actions to prevent it. One potential obstacle to this proposal is that it requires the forming of consensus and coordination with the powerful players who benefit from our current path and whose apparently near-total grip on this catastrophic future may itself discourage action. We then consider an alternative model based on Gilles Deleuze’s philosophy of the present–future relation. Although it has the branching structure that Dupuy is wary of, it may not suffer from the same problem of demotivation on account of the way it conceives the complex structure of the present event. For this reason, the Deleuzian model may be more suited to motivating action in a world where the future must be fought for rather than unanimously agreed upon.
CO2 Gas Temperature Sensing near Room Temperature by a Quantum Cascade Laser in Inter Pulse Mode
Authors: Herklotz Frank , Rubin Tom , von Haimberger Theodore , Heyne Karsten
Published: July 2022

A non-invasive CO2 gas temperature sensing technique at or close to the room temperature range based on quantum cascade laser absorption spectroscopy is presented. The method probes thermally populated ground state and hot-band rotational-vibrational transitions of CO2 in the frequency range from 2349 to 2351 cm−1 from which the gas temperature is obtained from Boltzmann statistics. Transmission spectra are recorded by injection-current driven frequency-scans, the so-called inter pulse mode, of a pulsed distributed feedback quantum cascade laser. The statistical uncertainty (1σ) in temperature for single frequency scans with time resolution of 10 ms is 4 K and can be further reduced down to ∼50 mK by long-time averaging of about 1 min. The technique is evaluated with particular emphasis on implementation, data acquisition, data analysis and potential improvements.
The Status of Genetic Resources and Olive Breeding in Tunisia
Authors: Debbabi Olfa Saddoud , Amar Fathi Ben , Rahmani Sameh Mnasri , Taranto Francesca , Montemurro Cinzia , Miazzi Monica Marilena
Published: July 2022

The olive tree, an iconic symbol of the Mediterranean basin, is the object of growing international interest in the production of olive oil for the world food market. In Tunisia, which is the fourth-largest producer of olive oil in the world, the production of olives and olive oil is of great socio-economic importance. Cultivation is widespread from north to south, but it is carried out using traditional techniques that results in extremely irregular production levels. To maintain their competitiveness on the international market, Tunisian producers must improve the quality of the oil through breeding plans that enhance the rich genetic heritage that is still not adequately exploited. The objective of this review is to present the state of olive breeding in Tunisia, illustrating the opportunities available for a better use of the rich Tunisian genetic heritage, the challenges it must face, and the need to multiply the efforts for sustainability, even in the light of the challenges posed by climate changes.
Amphipterygium adstringens (Schltdl.) Schiede ex Standl (Anacardiaceae): An Endemic Plant with Relevant Pharmacological Properties
Authors: Sotelo-Barrera Mireya , Cília-García Marcela , Luna-Cavazos Mario , Díaz-Núñez José Luis , Romero-Manzanares Angélica , Soto-Hernández Ramón Marcos , Castillo-Juárez Israel
Published: July 2022

Diseases, such as cancer, peptic ulcers, and diabetes, as well as those caused by drug-resistant infectious agents are examples of some of the world’s major public health problems. Amphipterygium adstringens (Schltdl.) Schiede ex Standl is an endemic tree to Mexico. Its stem bark has been used medicinally since pre-Hispanic times, but in recent decades it has been scientifically proven that it has properties that help counteract some diseases; extracts with organic solvents of the plant are outstanding for their anticancer, gastroprotective, and antimicrobial properties; terpenes and long-chain phenols have been identified as the main active compounds. Currently, overharvesting is causing a sharp reduction in natural populations due to an increase in demand for the stem bark by people seeking to improve their health and by national and transnational companies seeking to market it. Because of the growing interest of the world population and the scientific community, we reviewed recent studies on the bioactive properties of A. adstringens. Through the orderly and critical compendium of the current knowledge of A. adstringens, we provide a reference for future studies aimed at the rational use and protection of this valuable endemic natural resource.
Determination of Colchicine in Pharmaceutical Formulations, Traditional Extracts, and Ultrasonication-Based Extracts of Colchicum autumnale Pleniflorum (L.) Using Regular and Greener HPTLC Approaches: A Comparative Evaluation of Validation Parameters
Authors: Alqarni Mohammed H. , Shakeel Faiyaz , Aljarba Tariq M. , Abdel-Kader Maged S. , Zaatout Hala H. , Alshehri Sultan , Alam Prawez
Published: July 2022

In the literature, there is a scarcity of greener analytical approaches for colchicine (CLH) analysis. As a result, efforts were made in this study to develop and validate a greener reversed-phase high-performance thin-layer chromatography (HPTLC) technique for CLH analysis in traditional extracts (TE) and ultrasonication-based extracts (UBE) of commercial Unani formulations, commercial allopathic formulations, and Colchicum autumnale Pleniflorum (L.) obtained from Egypt and India. This new technique was compared to the regular normal-phase HPTLC method. The greenness profile of both methods was estimated using the Analytical GREENness (AGREE) approach. In the 100–600 and 25–1200 ng/band ranges, regular and greener HPTLC procedures were linear for CLH analysis, respectively. For CLH analysis, the greener HPTLC method was more sensitive, accurate, precise, and robust than the regular HPTLC method. For CLH analysis in TE and UBE of commercial Unani formulations, commercial allopathic formulations, and C. autumnale obtained from Egypt and India, the greener HPTLC method was superior in terms of CLH content compared to the regular HPTLC method. In addition, the UBE procedure was superior to the TE procedure for both methods. The AGREE scores for regular and greener reversed-phase HPTLC methods were found to be 0.46 and 0.75, respectively. The AGREE results showed excellent greener profile of the greener HPTLC method over the regular HPTLC technique. Based on several validation criteria and pharmaceutical assay findings, the greener HPTLC method is regarded as superior to the regular HPTLC approach.
Complete Genome Sequence of a Novel Monopartite Mastrevirus, Soybean Geminivirus B, Isolated from Soybean (Glycine max (L.) Merrill)
Authors: Choi Hoseong , Jo Yeonhwa , Hong Jinsung , Chung Hyunjung , Choi Sooyeon , Kim Sangmin , Lee Jeonghun , Moh Sanghyun , Lee Bongchoon , Cho Won Kyong
Published: July 2022

Soybean is one of the most important crops in Korea. To identify the viruses infecting soybean, we conducted RNA sequencing with samples displaying symptoms of viral disease. A contig displaying sequence similarity to the known Geminivirus was identified. A polymerase chain reaction (PCR) using two different pairs of back-to-back primers and rolling circle amplification (RCA) confirmed the complete genome of a novel virus named soybean geminivirus B (SGVB), consisting of a circular monopartite DNA genome measuring 2616 nucleotides (nt) in length. SGVB contains four open reading frames (ORFs) and three intergenic regions (IRs). IR1 includes a nonanucleotide origin of replication in the stem-loop structure. Phylogenetic and BLAST analyses demonstrated that SGVB could be a novel virus belonging to the genus Mastrevirus in the family Geminiviridae. We generated infectious clones for SGVB by adding a copy of the IR1 region of SGVB, comparing the V-ori in addition to the full-length genome of SGVB. Using the infectious clones, we observed chlorosis and leaf curling with a latent infection in the inoculated Nicotiana benthamiana plants, while none of the inoculated soybean plants showed any visible symptoms of disease. This study provides the complete genome sequence and infectious clones of a novel Mastrevirus referred to as SGVB from soybean in Korea.
The Modified Brière Equation and Its Applications
Authors: Jin Jun , Quinn Brady K. , Shi Peijian
Published: July 2022

The Brière equation (BE) is widely used to describe the effect of temperature on the development rate of insects, and it can produce both symmetrical and asymmetrical bell-shaped curves. Because of its elasticity in curve fitting, the integrated form of BE has been recommended for use as a sigmoid growth equation to describe the increase in plant biomass with time. However, the start time of growth predicted by the sigmoid growth equation based on the BE is not completely comparable to empirical crop growth data. In the present study, we modified the BE by adding an additional parameter to further increase its elasticity for data fitting. We termed this new equation the modified Brière equation (MBE). Data for the actual height and biomass of 15 species of plants (with two cultivars for one species) were fit with the sigmoid growth equations based on both the BE and MBE assuming that the growth start time was zero for both. The goodness of fit of the BE and MBE sigmoid growth equations were compared based on their root-mean-square errors and the corresponding absolute percentage error between them when fit to these data. For most species, we found that the MBE sigmoid growth equation achieved a better goodness of fit than the BE sigmoid growth equation. This work provides a useful tool for quantifying the ontogenetic or population growth of plants.
Integration of Kazakhstan Technologies for Silicon and Monosilane Production with the Suitable World Practices for the Production of Solar Cells and Panels
Authors: Serikkanov Abay , Shongalova Aigul , Zholdybayev Kairat , Tokmoldin Nurlan , Turmagambetov Tleuzhan , Pavlov Artem , Mukashev Bolat
Published: July 2022

In this review article, the state of the art of the complete processing chain in the production of solar photo-electric modules from raw materials (quartzites, quartz sand) is detailed. In particular, the silicon and silane production technologies of the Institute of Physics and Technology of Almaty, Kazakhstan, can become part of an expansive technologies chain. Such integration could present a number of benefits in comparison with the analogs, including less environmental pressure and increased safety. The combination of innovative production technologies of highly effective solar cells and modules with competitive production technologies of solar-grade silicon and silane constitutes a basis for the creation of an industrial cluster in the field of silicon solar photo energy with a complete vertically integrated production cycle.
Effects of Water Content and Irrigation of Packing Materials on the Performance of Biofilters and Biotrickling Filters: A Review
Authors: Danila Vaidotas , Zagorskis Alvydas , Januševičius Tomas
Published: July 2022

Biofilters (BFs) and biotrickling filters (BTFs) are two types of bioreactors used for treatment of volatile organic compounds (VOCs). Both BFs and BTFs use packing materials in which various microorganisms are immobilised. The water phase in BFs is stationary and used to maintain the humidity of packing materials, while BTFs have a mobile liquid phase. Optimisation of irrigation of packing materials is crucial for effective performance of BFs and BTFs. A literature review is presented on the influence of water content of packing materials on the biofiltration efficiency of various pollutants. Different configurations of BFs and BTFs and their influence on moisture distribution in packing materials were discussed. The review also presents various packing materials and their irrigation control strategies applied in recent biofiltration studies. The sources of this review included recent research articles from scientific journals and several review articles discussing BFs and BTFs.
An Investigation on the Features of Deformation and Residual Stress Generated by Patch Welding with Different Plate Sizes
Authors: Hashiguchi Takehito , Hirohata Mikihito , Jármai Károly
Published: July 2022

Welding is widely used to manufacture and repair steel structures such as piping and pressure vessels. Welding induces deformation and residual stress, which influences the mechanical performance of the structural members. Noting patch welding, which is applied to repair steel structures, a series of patch welding experiments and numerical analyses were carried out. The features of out-of-plane deformation and residual stress by patch welding were examined by changing the patch size. The out-of-plane deformation showed different modes in the patch joints. The magnitude of the out-of-plane deformation depended on the patch size. The tensile residual stress at the weld toe increased with the enlargement of the patch size. The costs for the different sizes of patch welding were estimated for choosing the patch size reasonably. The patch size should be determined by considering the mechanical influences of welding and the economic viewpoints of the welding process.
Changing the Academic Gender Narrative through Open Access
Authors: Wilson Katie , Huang Chun-Kai (Karl) , Montgomery Lucy , Neylon Cameron , Handcock Rebecca N. , Ozaygen Alkim , Roelofs Aniek
Published: July 2022

In this article, we ask whether dominant narratives of gender and performance within academic institutions are masking stories that may be both more complex and potentially more hopeful than those which are often told using publication-related data. Influenced by world university rankings, institutions emphasise so-called ‘excellent’ research practices: publish in ‘high impact’, elite subscription journals indexed by the commercial bibliographic databases that inform the various ranking systems. In particular, we ask whether data relating to institutional demographics and open access publications could support a different story about the roles that women are playing as pioneers and practitioners of open scholarship. We review gender bias in scholarly publications and discuss examples of open access research publications that highlight a positive advantage for women. Using analysis of workforce demographics and open research data from our Open Knowledge Initiative project, we explore relationships and correlations between academic gender and open access research output from universities in Australia and the United Kingdom. This opens a conversation about different possibilities and models for exploring research output by gender and changing the dominant narrative of deficit in academic publishing.
Public Lament and Intra-Faith Worship in an Appalachian Context
Authors: Elkins Heather Murray , Allen Jeffrey S.
Published: July 2022

On 5 April 2010, the largest mining disaster in the US since 1970 occurred at the Upper Big Branch Mine in West Virginia. Twenty-five miners were known to have died in the explosion, with the fates of four miners unknown. Families of the twenty-nine miners gathered together at the mine site as they awaited word as to which of the miners died and who had survived. On 6 April, the Red Cross invited representatives from the West Virginia Council of Churches to the mine site to help organize pastoral support for the families. On the evening of 10 April, five days after the explosion, word came that all of the 29 miners had died in the initial explosion. Governor Joe Manchin declared, on 25 April, for a public memorial service for the miners—an event attended by several thousand worshipers and led by clergy, denominational leaders, and public officials, including President Barack Obama, Vice President Joe Biden, Senator Robert C. Byrd, and Governor Manchin. This collaborative essay traces how the pastoral, political, and relational response to trauma shaped this liturgical form. Given the oral traditions of the region, narrative will be one of the primary structures for analysis, and testimony is central to this public worship. A public secular ritual with its goals of unity and inter-riting of distinct religious voices and identities will provide a grammar for reading the service.
Exploring the Determinants of School Bus Crash Severity
Authors: Lidbe Abhay , Adanu Emmanuel Kofi , Tedla Elsa , Jones Steven
Published: July 2022

Although the school bus is considered a safe form of transportation, school bus crashes are a major safety concern. School bus crashes are a result of driver error of either the at-fault school bus or another at-fault vehicle (where the school bus is not at fault). To examine the risk factors associated with school bus related crashes and crash outcomes, this study segments and develops two binary logit models for each school bus crash type. A total of 1702 school bus related crashes recorded between 2009 and 2016 were used to estimate the model. According to the model results, sideswipe collisions were less likely to result in injury outcomes for at-fault school buses than rear-end and side-impact collisions. Speeding, driving impaired or under the influence, and negotiating a curve all have significant positive associations with injury outcomes in not-at-fault school bus crashes. This study’s practical implications include enforcing the school bus safe driving guidelines, training programs for school bus drivers that include elements of nonroutine trips, training for crossing guards, and awareness programs for drivers of other vehicles to instill safe driving practices around school buses.
Predictive Model for the Diagnosis of Uterine Prolapse Based on Transperineal Ultrasound
Authors: García-Mejido José Antonio , Ramos-Vega Zenaida , Fernández-Palacín Ana , Borrero Carlota , Valdivia Maribel , Pelayo-Delgado Irene , Sainz-Bueno José Antonio
Published: July 2022

We want to describe a model that allows the use of transperineal ultrasound to define the probability of experiencing uterine prolapse (UP). This was a prospective observational study involving 107 patients with UP or cervical elongation (CE) without UP. The ultrasound study was performed using transperineal ultrasound and evaluated the differences in the pubis–uterine fundus distance at rest and with the Valsalva maneuver. We generated different multivariate binary logistic regression models using nonautomated methods to predict UP, including the difference in the pubis–uterine fundus distance at rest and with the Valsalva maneuver. The parameters were added progressively according to their simplicity of use and their predictive capacity for identifying UP. We used two binary logistic regression models to predict UP. Model 1 was based on the difference in the pubis–uterine fundus distance at rest and with the Valsalva maneuver and the age of the patient [AUC: 0.967 (95% CI, 0.939–0.995; p < 0.0005)]. Model 2 used the difference in the pubis–uterine fundus distance at rest and with the Valsalva maneuver, age, avulsion and ballooning (AUC: 0.971 (95% CI, 0.945–0.997; p < 0.0005)). In conclusion, the model based on the difference in the pubis–uterine fundus distance at rest and with the Valsalva maneuver and the age of the patient could predict 96.7% of patients with UP.
Heavy Metal Contamination in Sediments from Wetlands Invaded by Spartina alterniflora in the Yellow River Delta
Authors: Zhang Zaiwang , Zhang Tongrui , Yu Wenhao , Xu Jikun , Li Jialiang , Wu Tao , Liu Suzhe , Wang Haiyang , Wang Yuxia , Shang Shuai , Lin Aiguo
Published: July 2022

Heavy metals are major pollutants that pose threats to wetland environments. In the present study, surface sediments from wetlands vegetated by invasive species Spartina alterniflora in the Yellow River Delta were collected and determined for the mass fractions of Co, Ni, As, Cd and Pb. Results showed mass fractions of Co, Ni, As, Cd and Pb in the sediments of the S. alterniflora communities ranged from 8.5 to 16.0, 13.9–27.9, 3.2–13.8, 0.08–0.24, and 17.6–37.5 mg/kg dw, respectively, generally presenting an order of Pb > Ni > Co > As > Cd. The levels of heavy metals in sediments in the S. alterniflora communities were higher than those in the wetland vegetated by the native plant species Suaeda heteroptera. Correlations among metal elements were highly significant, suggesting that they might have the same sources. Clay and TOC were important factors affecting the spatial distribution of metals. The Igeo values of the investigated elements in the sediments were frequently lower than 0, revealing the slight pollution status of these metals. Relatively slight values of Eri and RI suggested that the potential ecological risks caused by the 5 metals were low. Our findings could provide a better understanding of the correlation between metal pollution and bio-invasion in wetland ecosystems.
Near-Horizon Thermodynamics of Hairy Black Holes from Gravitational Decoupling
Authors: Cavalcanti Rogerio Teixeira , Alves Kelvin dos Santos , Hoff da Silva Julio Marny
Published: July 2022

The horizon structure and thermodynamics of hairy spherically symmetric black holes generated by the gravitational decoupling method are carefully investigated. The temperature and heat capacity of the black hole is determined, as well as how the hairy parameters affect the thermodynamics. This allows for an analysis of thermal stability and the possible existence of a remanent black hole. We also calculate the Hawking radiation corrected by the generalized uncertainty principle. We consider the emission of fermions and apply the tunneling method to the generalized Dirac equation. This shows that, despite the horizon location being the same as the Schwarzschild one for a suitable choice of parameters, the physical phenomena that occur near the horizon of both black holes are qualitatively different.
Exploring Sea Lice Vaccines against Early Stages of Infestation in Atlantic Salmon (Salmo salar)
Authors: Casuso Antonio , Valenzuela-Muñoz Valentina , Benavente Bárbara P. , Valenzuela-Miranda Diego , Gallardo-Escárate Cristian
Published: July 2022

The sea louse Caligus rogercresseyi genome has opened the opportunity to apply the reverse vaccinology strategy for identifying antigens with potential effects on lice development and its application in sea lice control. This study aimed to explore the efficacy of three sea lice vaccines against the early stage of infestation, assessing the transcriptome modulation of immunized Atlantic salmon. Therein, three experimental groups of Salmo salar (Atlantic salmon) were vaccinated with the recombinant proteins: Peritrophin (prototype A), Cathepsin (prototype B), and the mix of them (prototype C), respectively. Sea lice infestation was evaluated during chalimus I-II, the early-infective stages attached at 7-days post infestation. In parallel, head kidney and skin tissue samples were taken for mRNA Illumina sequencing. Relative expression analyses of genes were conducted to identify immune responses, iron transport, and stress responses associated with the tested vaccines during the early stages of sea lice infection. The vaccine prototypes A, B, and C reduced the parasite burden by 24, 44, and 52% compared with the control group. In addition, the RNA-Seq analysis exhibited a prototype-dependent transcriptome modulation. The high expression differences were observed in genes associated with metal ion binding, molecular processes, and energy production. The findings suggest a balance between the host’s inflammatory response and metabolic process in vaccinated fish, increasing their transcriptional activity, which can alter the early host–parasite interactions. This study uncovers molecular responses produced by three vaccine prototypes at the early stages of infestation, providing new knowledge for sea lice control in the salmon aquaculture.
Post-Vaccinal Encephalitis with Early Relapse after BNT162b2 (COMIRNATY) COVID-19 Vaccine: A Case Report
Authors: Vences Miguel A. , Canales Diego , Albujar Maria Fe , Barja Ebelin , Araujo-Chumacero Mary M. , Cardenas Edu , Alvarez Arturo , Urrunaga-Pastor Diego
Published: July 2022

We describe the case of a 72-year-old man who received the first dose of the BNT162b2 (COMIRNATY) vaccine against COVID-19 on 18 May 2021, and the second dose on 9 September 2021. One day after receiving the first dose, he cursed with malaise, headache, fever, confusion, aggressiveness, and gait alterations. We performed serum and cerebrospinal fluid (CSF) tests (finding elevated proteins in CSF) with negative results for infectious, systemic, and neoplastic causes. We performed brain nuclear magnetic resonance imaging (MRI), finding circumscribed encephalitis at the anterior frontal and bilateral temporal lobes. We were unable to perform a panel of antineuronal antibodies. The patient was readmitted due to early clinical relapse four days after receiving his second dose. We found sequelae lesions at the frontal level but with new demyelinating lesions at the left temporal level in brain MRI. We indicated methylprednisolone, and he presented a favorable improvement. We report an encephalitis case of probable autoimmune etiology after vaccination with BNT162b2, which presented early clinical relapse after receiving the second dose and presented a favorable response to methylprednisolone.
COVID-19 Vaccination Drive in a Low-Volume Primary Care Clinic: Challenges & Lessons Learned in Using Homegrown Self-Scheduling Web-Based Mobile Platforms
Authors: Agarwal Reita N. , Aggarwal Rajesh , Nandarapu Pridhviraj , Aggarwal Hersheth , Verma Ashmit , Haque Absarul , Tripathi Manish K.
Published: July 2022

Background: The whole of humanity has suffered dire consequences related to the novel coronavirus disease 2019 (COVID-19). Vaccination of the world base population is considered the most promising and challenging approach to achieving herd immunity. As healthcare organizations took on the extensive task of vaccinating the entire U.S. population, digital health companies expanded their automated health platforms in order to help ease the administrative burdens of mass inoculation. Although some software companies offer free applications to large organizations, there are prohibitive costs for small clinics such as the Good Health Associates Clinic (GHAC) for integrating and implementing new self-scheduling software into our e-Clinical Works (ECW) Electronic Health Record (EHR). These cost burdens resulted in a search that extended beyond existing technology, and in investing in new solutions to make it easier, more efficient, more cost-effective, and more scalable. Objective: In comparison to commercial entities, primary care clinics (PCCs) have the advantage of engaging the population for vaccination through personalized continuity of clinical care due to good rapport between their patients and the PCC team. In order to support the overall national campaign to prevent COVID-19 infections and restore public health, the GHAC wanted to make COVID-19 vaccination accessible to its patients and to the communities it serves. We aimed to achieve a coordinated COVID-19 vaccination drive in our community through our small primary care clinic by developing and using an easily implementable, cost-effective self-registration and scheduling web-based mobile platform, using the principle of “C.D.S. Five Rights”. Results: Overall, the Moderna vaccination drive using our developed self-registration and scheduling web portal and SMS messaging mobile platform improved vaccination uptake (51%) compared to overall vaccination uptake in our town, county (36%), and state (39%) during April–July 2021. Conclusions: Based on our experience during this COVID-19 vaccination drive, we conclude that PCCs have significant leverage as “invaluable warriors”, along with government and media education available, to engage patients for vaccination uptake; this leads to national preventive health spread in our population, and reduces expenses related to acute illness and hospitalization. In terms of cost-effectiveness, small PCCs are worthy of government-sponsored funding and incentives, including mandating EHR vendors to provide free (or minimal fee) software for patient self-registration and scheduling, in order to improve vaccination drive access. Hence, improved access to personalized informative continuity of clinical care in the PCC setting is a “critical link” in accelerating similar cost-effective campaigns in patient vaccine uptake.
A New Sampling Approach for the Detection of Swine Influenza a Virus on European Sow Farms
Authors: Lillie-Jaschniski Kathrin , Lisgara Marina , Pileri Emanuela , Jardin Agnes , Velazquez Eduardo , Köchling Monika , Albin Michael , Casanovas Carlos , Skampardonis Vassilis , Stadler Julia
Published: July 2022

Swine influenza A virus (swIAV), which plays a major role in the porcine respiratory disease complex (PRDC), is eliminated from the respiratory tract within 7–9 days after infection. Therefore, diagnosis is complicated in endemically infected swine herds presenting no obvious clinical signs. This study aimed to investigate the right time point for sampling to detect swIAV. A cross-sectional study was performed in 131 farms from 12 European countries. The sampling protocol included suckling piglets, weaners, and nursery pigs. In each age group, 10 nasal swabs were collected and further examined in pools of 5 for swIAV by Matrix rRT-PCR, followed by a multiplex RT-PCR to determine the influenza subtype. SwIAV was detected in 284 (37.9%) of the samples and on 103 (78.6%) farms. Despite the highest number of animals with clinical signs being found in the nursery, the weaners were significantly more often virus-positive compared to nursery pigs (p = 0.048). Overall, the swIAV detection rate did not significantly differ between diseased or non-diseased suckling and nursery piglets, respectively; however, diseased weaners had significantly more positive pools than the non-diseased animals. Interestingly, in 9 farms, different subtypes were detected in different age groups. Our findings indicate that to detect all circulating swIAV subtypes on a farm, different age groups should be sampled. Additionally, the sampling strategy should also aim to include non-diseased animals, especially in the suckling period.
Pengaruh Good Corporate Social Responsibilit (CSR), Return On Assets (ROA), Return On Equity (ROE), Debt To Equity Ratio (DER) terhadap Nilai Perusahaan (Study Empiris Perusahaan yang Tercatat di LQ45 Periode 2016-2018)
Authors: Pranita Fera Lufhidarani
Published: July 2022

Penelitian ini bertujuan untuk menganalisis dan mengetahui pengaruh Corporate Social Responsibility (CSR), Return On Asset (ROA), Return On Equity (ROE)  dan  Debt to Equity Ratio (DER) terhadap Nilai Perusahaan,pada perusahaan yang tercatat di LQ45 periode 2016-2018. Metode pendekatan Analisis Regresi Linear Berganda dengan menggunakan metode kuantitatif untuk mengetahui apakah terdapat pengaruh yang signifikan antara variable terhadap Nilai Perusahaan,pada perusahaan yang tercatat di LQ45 periode 2016-2018. Sampel dalam penelitian ini diambil melalui kriteria purposive sampling sehingga didapatakan sebanyah 28 Perusahaan yang memenuhi kriteria dari 45 perusahaan yang tercatat di LQ45 pada periode 2016-2018. Dari hasil penelitian yang diperoleh bahwa secara parsial CSR berpengaruh negative terhadap Nilai Perusahaan, Perusahaan dengan pengungkapan CSR yang tinggi akan berakibat pada tingginya beban yang harus dikeluarkan perusahaan untuk melakukan kegiatan CSR tersebut, sehingga akan berdampak pada berkurangnya laba yang diperoleh perusahaan dan akan berdampak pada penurunan nilai perusahaan. ROA (Return on Asset) yang diperoleh perusahaan akan berpengaruh terhadap nilai perusahaan dimana semakin tinggi keuntungandari asset perusahaan akan mempengaruhi pula laba yang diperoleh perusahaan begitu pula dengan ROE rasio rentabilitas modal sendiri yang tinggi menandakan tingginya keberhasilan pucuk pimpinan perusahaan dalam mengemban misi dari pemiliknya. serta  DER dimana Konsep leverage ini penting bagi investor dalam membuat pertimbangan penilaian saham. Para investor umumnya cenderung menghindari risiko. Risiko yang timbul dalam penggunaan financial leverage disebut dengan financial risk yaitu risiko tambahan yang dibebankan kepada pemegang saham sebagai hasil penggunaan utang oleh perusahaan. Semakin tinggi leverage, semakin besar risiko keuangannya dan sebaliknya.
Aplikasi Klasifikasi SMS Berbasis Web Menggunakan Algoritma Logistic Regression
Authors: Pramakrisna Fitran Dwi , Adhinata Faisal Dharma , Tanjung Nia Annisa Ferani
Published: July 2022

Jenis SMS spam adalah jenis pesan teks yang tidak diinginkan atau tidak diminta yang dikirim ke ponsel pengguna, seringkali untuk tujuan komersial. Untuk mengatasi masalah spam, diperlukan teknik untuk memilah kata atau kalimat termasuk spam atau bukan spam. Pada penelitian ini diusulkan menggunakan machine learning untuk mengklasifikasikan pesan mana yang spam dan mana yang tidak spam. Data yang digunakan pada penelitian ini terdiri dari 1140 pesan, dimana sudah diberi label 0 untuk pesan yang tidak spam dan 1 untuk pesan yang spam. Algoritma yang digunakan untuk kasus ini adalah Logistic Regression. Hasil penelitian menunjukkan model memiliki tingkat akurasi untuk mengklasifikasi pesan, sebesar 97%. Aplikasi yang dikembangkan untuk menerapkan hasil pemodelan machine learning menggunakan bentuk sebuah website sederhana dengan bantuan Flask framework dari Python. Hasil akhir dari aplikasi ini adalah model machine learning yang dapat dibuka melalui website.
Defeito do septo ventricular em cães e gatos, uma revisão / Ventricular septal defect in dogs and cats, a review
Authors: Sartorelli Matheus de Moraes , Kerchener Alice , Moraes Júlia Vulpini de , Feder Gabriela , Vanzella Luiza
Published: July 2022

O defeito do septo ventricular (DSV) tem origem no desenvolvimento incompleto ou no desalinhamento do septo interventricular (SIV) ainda durante o estágio embrionário, de forma congênita. Anatomicamente, o DSV define-se por orifícios de números, tamanhos e formas variadas no SIV, estando, por vezes, associado a outros defeitos cardíacos. Quanto à prevalência, encontra-se com maior frequência em Buldogues ingleses e, em relação à anatomia, tem maior ocorrência na região membranosa do septo interventricular, muitas vezes ocasionando em defeitos perimembranosos. A comunicação interventricular desenvolve-se levando a um desvio intracardíaco da esquerda para a direita devido aos níveis de maior pressão sistólica e, quando ao contrário - da direita para a esquerda - resulta em cianose, quadro sugestivo de desvios mais graves.  Pequenos DSVs não resultam em sinais clínicos, entretanto, predispõem a endocardite frequentemente, além do fechamento espontâneo dos orifícios ser raro em cães e gatos. O DSV pode ainda ocasionar em regurgitação da aorta com prolapso diastólico dos folhetos valvares, devido à irrigação inadequada da artéria. Clinicamente, a maioria dos casos são assintomáticos e, quando sintomáticos, manifestam-se frequentemente através da intolerância ao exercício, tosse, dispneia e por meio de sinais da Insuficiência Cardíaca Congestiva (ICC) esquerda. O aumento da velocidade do fluxo e da turbulência nos orifícios do SIV causam sopro holossistólico, mais reconhecível no hemitórax direito. O diagnóstico associa fatores como histórico, sinais clínicos, exame físico e, precisamente, a ecoDopplercardiografia onde averígua-se o fluxo do desvio do DSV. O tratamento engloba a oclusão cirúrgica de peito aberto e os métodos transcateteres com uso de oclusores. De forma paliativa se considera como tratamento, em casos específicos, a colocação cirúrgica de bandagem constritiva em torno do tronco pulmonar.
Comportamiento productivo de búfalas lecheras (Bubalus bubalis) en la provincia Granma, Cuba / Productive performance of dairy buffaloes (Bubalus bubalis) in Granma province, Cuba
Authors: Pérez Yankiel Enrique Ramírez , Reyes Bánier Ramírez , Núñez Yosbany Espinosa , Borroto Odilia Gutiérrez
Published: July 2022

La ganadería bubalina forma parte de una estrategia económica del país, conocer esta especie es de gran utilidad por su aporte a la alimentación humana. El objetivo de esta investigación fue caracterizar el comportamiento productivo de búfalas lecheras en la Empresa Agropecuaria Bayamo, provincia de Granma, con promedios mensuales de precipitaciones en el orden de 608,5 a 1264,9 mm3. Para ello, se utilizaron datos contenidos en tarjetas individuales de 125 reproductoras en el período 2011-2015. Para modelar la curva de producción se aplicaron las funciones cuadrática logarítmica y exponencial a 592 pesajes  de 96 búfalas de río. La organización, descripción y procesamiento de datos se realizó con los sistemas Microsoft Excel y SPSS versión 22. Para cada indicador se obtuvo la media, desviación estándar, y coeficiente de variación. El rebaño concentró el 78,54% de los nacimientos entre Agosto y Noviembre, la edad de incorporación fue 27,85±2,19 meses, y condicionó retrasos en la edad al primer parto con 38,81±4,95 meses, la edad promedio del rebaño e intervalo entre partos fueron de 8,85 años y 385,04 días respetivamente. El porciento de búfalas en ordeño incrementó de 61,83% en el primer año, hasta 92,83% en el último. El rendimiento lechero osciló entre 6,32 ± 2,30 a 1,83 ± 1,52 kg/d.  Se concluyó que las búfalas muestran una estacionalidad reproductiva asociada al régimen de lluvias y la disponibilidad de alimento, ubicando la época de partos entre los meses de agosto a noviembre, como consecuencia los niveles productivos se elevan en el periodo poco lluvioso. La función que mejor describió la curva de producción fue la cuadrática logarítmica con una curva típica para producción de leche en pastoreo, que evidenció un crecimiento inicial seguido de un pico discreto y una fase decreciente pronunciada.