bluuebunny/crossref_metadata_2025 huggingface dataset:
Economic security guaranteeing entities
Authors: Hrytsyshen Dymytriy O. , Dykyy Anatoliy P. , Butuzov Vitaliy M.
Published: April 2024

The article studies the features and establishment of specific features of law enforcement agencies and the peculiarities of financing the activities of entities ensuring the implementation of law enforcement functions and determines strategic directions for reforming the activities of the entities ensuring the implementation of law enforcement functions. The concept of “law enforcement agency” and signs and vectors of institutional support for the implementation of state policy in the field of law enforcement are defined, including 1) creation of special law enforcement agencies to prevent and counter the most important social problems: cybercrime; distribution and production of drugs; 2) shaping a communication strategy for the interaction of law enforcement agencies; 3) establishment of a permanent representation of Europol. An analysis of state budgets for 2019-2023 is carried out to assess the level of financial support for law enforcement agencies and state authorities performing law enforcement functions. The role and main tasks of the Bureau of Economic Security are determined. Priority directions for expanding the activities of law enforcement agencies in the context of preventing and countering economic crime are proposed. Ways of organizing joint activities of law enforcement agencies are proposed: creation of joint investigation groups, involvement of specialists, joint use of resources, exchange of information, and consultations. The state of financing the activities of law enforcement agencies is studied, and the following areas of improvement of this process are suggested: forecasting the covert expenditures for special operations; reporting to the profile committee of the Parliament of Ukraine; development of a financing mechanism for joint operations; financing the interaction of law enforcement agencies with international police organizations; financing the continuous education of law enforcement officers; financing the retraining of law enforcement officers of working age who stop working in the law enforcement system; provision of funding for the creation of scientific laboratories; financing the temporary joint investigative interagency groups; financing the study of economic and financial aspects of war crimes. The article proposes directions for the expansion of the activities of law enforcement agencies, in particular: the priority areas of joint activity of law enforcement agencies in the implementation of the state policy of prevention and counteraction of economic crime are defined; the form of organization of joint activity of law enforcement agencies in the implementation of the state policy of prevention and counteraction of economic crime is substantiated.
Research on public policy of the customs administration in scientific works
Authors: Koroshchenko Mykola M.
Published: April 2024

The article analyzes the public policy, in particular the public policy of the customs administration, in scientific works. Public policy provides for a government plan and guiding strategy for solving a social problem, intervention, service delivery, and public works, as well as the limits of citizens’ responsibility to the state on specific issues. The public policy of the customs administration covers various sectors of national and international engagement. The article suggests taking more active care of the public, which makes it possible to really move from manageability to governance as a model of public administration, which involves citizens in making public decisions that are less hierarchical than in the Weber model, more transparent, and the citizen’s duty is to participate in public debates through exercises of public reasonableness. This requires critical thinking, culture, balance, and constant participation in public affairs and public policy. It is important to perceive participation as a political action and as a right, where the former implies recognizing it as a set of actions aimed at influencing the political process through voting, discussion, debate, even social protest, and the exercise of permanent civil control over the authorities. Therefore, the analysis of the impact of ideas on public policy is hindered by problems that arise due to inaccuracies in determining what ideas are, where they come from, when and how they change, and how to study them. By this time, ideologue scientists have provided us with classifications of different types of ideas (different levels of generality, from specific political programs to comprehensive cultures), as well as different ways of thinking about ideas (from positivist to constructivist approaches, emphasizing ideas as causes or constitutive elements of public policy). The use of this concept in various sub-disciplines resulted in its expansion to cover a range of phenomena and concepts, making it almost impossible to understand what is ideological and what is not. The above definitions are far from an exhaustive list, but they are more than enough to determine some of the main characteristics. In such circumstances, customs administrations as services that carry out and regulate international trade and the movement of goods face increasingly important and complex tasks. At the same time, customs administrations are expected to promote the development of international trade.
Вasic methods of strategic management of commodity flows in the domestic market
Authors: Yakhno Tetyana P.
Published: April 2024

The internal market as a factor in the efficiency of reproduction processes is an effective engine for other branches of the national economy. With the help of the mechanism of supply and demand coordination, the market provides effective business relations. However, today the functions of market self-regulation are necessarily combined with the functions of the state regulation mechanism. Considering today’s problems, the regulation of the consumer market should be carried out according to a three-level system: at the central level, at the level of regions, and at the level of local governments. At each level, appropriate structural subdivisions with their specific tasks and functions should be created. The main task of society in regulating the consumer goods market is to optimize the circulation of goods. It is obvious that the lack of an effective mechanism is a serious destructive factor in the development of the sphere of consumer circulation in the modern economy. At the present stage, strategic planning is one of the principal management functions and in no way can be overlooked by either practitioners or scientists. From various aspects of planning (operational, current, prospective), the majority of experts now pay maximum attention to the prospective one, which is based on models of the enterprise development strategy in the conditions of the changing external and internal environment. The strategy is implemented in the context of the organization’s mission, and its fundamental objective is to ensure that the mission is connected with the organisation’s main goals in the changing economic environment. A person is always a potential creator of the necessary conditions for the evolution of society, and such action is determined through the mechanisms of consumption. Therefore, consumption should be considered as a process of satisfying needs with material and spiritual goods, which generates motivation to work, involves the use of the social product of certain needs, and is the final sign of social reproduction. The article examines the theoretical foundations of methods of strategic management of commodity flows at the micro level. The tasks of forming an organizational and economic mechanism for managing commodity flows (macro level), which provides the optimal variant for the movement of goods are defined. A mathematical description of the general equilibrium is presented. The basic methods of managing intra-production commodity flows at the micro level are formulated. The authoritarian solution of the rationing mechanism is substantiated, and the difficulties of implementing the rationing mechanism are outlined.
THE CORROSION INHIBITION EFFECT ON THE ALUMINUM ALLOY AZ91C'S FATIGUE BEHAVIOR IN THE SALINE ENVIRONMENT
Authors:   Mechanical Engineering Department, Higher Institute for Sciences and Technology, Tobruk, Libya, SALEH Mohammed S.R. , EL-GAROSHI Magdi E.M. ,   Mechanical Engineering Department, Higher Institute for Sciences and Technology, Tobruk, Libya, FADIEL Ali F. Ali ,   Mechanical Engineering Department, Higher Institute for Sciences and Technology, Tobruk, Libya, KHALID Hafiez M.B. ,   Mechanical Engineering Department, Higher Institute for Sciences and Technology, Tobruk, Libya
Published: April 2024

Investigations were made into the fatigue in the magnesium alloy AZ 91C cast in corrosive fluids and air at varied NaCl solution concentrations. Fatigue specimens will be subjected to surface stress testing in corrosive conditions with a stress amplitude of 75 MPa both after and before coating. To comprehend the behavior of the magnesium material, its fatigue life, corrosion product (X-ray spectra), and fracture properties will be examined. The corroding medium (NaCl) has been found to significantly shorten the fatigue life of the magnesium alloy AZ91C. Chemical conversion treatment was applied to the AZ91C alloy to improve corrosion resistance and corrosion fatigue resistance. MgSnO3 was found in the XRD patterns of the stannite-treated AZ91C alloy, and this treatment slightly improved the alloy's corrosion resistance in an alkaline stannite solution with a pH of 7. H2O and SEM images demonstrate that chloride ions can penetrate the substrate through porous structures.
MICROWAVE ABSORBERS BASED ON MÖBIUS STRIP RESONATORS
Authors:   Belarusian State University of Informatics and Radioelectronics (Minsk, Belarus), BOIPRAV Olga V. , BOGUSH Vadim A. ,   Belarusian State University of Informatics and Radioelectronics (Minsk, Belarus), CHELYADINSKY Vladislav S. ,   Belarusian State University of Informatics and Radioelectronics (Minsk, Belarus)
Published: April 2024

The paper deals with technology of manufacturing of microwave absorbers with ordered and structured surface layer. This layer contains Möbius strip resonators, located on the fixed distance from each other. The technology was developed by the authors on the base of the following data: 1) results of theoretical study of microwaves interaction with Möbius strip resonator; 2) results of experimental study of electromagnetic radiation reflection, transmission and absorption coefficients in the microwave frequency range of the experimental samples of microwave absorbers based on Möbius strip resonators, which differ by the distance between these resonators. It was established on the base to the listed results that the microwave absorbers manufactured in accordance to the technology proposed by the authors are wide-band ones. Electromagnetic radiation absorption coefficient values of these absorbers changes from 0.5 to 0.97 in frequency range 2.0–17.0 GHz if the distance between the Möbius strip resonators containing in their surface layer, is 15.0 mm. If the distance between the Möbius strip resonators containing in the surface layer of the considered absorbers is less than 15.0 mm their electromagnetic radiation absorption coefficient in the indicated frequency bands is lower than presented values. The considered absorbers are promising for use in shielded rooms and anechoic chambers.
Management of Thrombocytopenia with Partial Splenic Embolization in Liver Cirrhosis
Authors: Putri Septia Harma , Arnelis  , Saptino Miro
Published: April 2024

Thrombocytopenia is a frequent complication in patients with cirrhosis. Thrombocytopenia is generally divided into mild, moderate, and severe thrombocytopenia. Thrombocytopenia in liver cirrhosis not only increases the risk of bleeding during surgery but can also have an impact on patient management, such as liver biopsy, administration of antiviral therapy, and postponement of elective surgery. The pathophysiology of thrombocytopenia in chronic liver disease can be caused by decreased platelet production, sequestration in the spleen, and increased platelet destruction. Partial splenic embolization (PSE) is one option for treating thrombocytopenia in chronic liver disease. PSE is an effective procedure in treating complications associated with hypersplenism and portal hypertension, such as esophageal varices, pancytopenia, portal hypertensive gastropathy and ascites.
Exploring Anticancer Potential of Camptothecin Isolated from Nothapodytes Nimmonianain the Treatment of Prostate and Lung Carcinoma
Authors: Galatage Sunil T , Manjappa Arehalli S , Katkar Rushikesh B , Shinde Sumit A , Phalake Ramanand A , Kadam Rahul J , K Gourisankar , P Shyamsundar , Bhagwat Durgacharan , Bille Kranti S
Published: April 2024

Background: Cancer is a life-threatening disease which is a major threat to global health which continues to affect predominantly in developing nations. Present research work has been oriented towards the determination of the anticancer potential of camptothecin (CPT) as herbal medicine for the treatment of prostate and lung carcinoma. 
Methods: Structural determination of camptothecin has been performed by different analytical techniques where anticancer potential was tested by MTT assay, Flow cytometry and DAPI on A549 and LNCaP cells lines. 
Results: FTIR spectra of camptothecin showed peaks related to specific structure which is nearly equal to standard structure of CPT. NMR spectra of camptothecin showed specific peaks in the region of delta 8.686 - 5.279, the signals of H-7 related to structural features similar to camptothecin. LCMS spectra of camptothecin showed mean retention time at 3.620 and covered 100 % area along with mass spectra gives precursor m/z peak at 349.2 [M+H]+ matches to standard molecular weight of camptothecin. CPT has been used as competent alternative to systemic chemotherapy to cure lung and prostate carcinoma having IC50 value 3.421 μg /ml and 5.253μg /ml respectively. CPT successfully induces apoptosis in A549 and LNCaP cell lines 72.12 ± 3.45 % and 66.41 ± 4.50 % as compared to control 4.28 ± 1.78 and 1.52 ± 0.58 respectively which was proved by DAPI and flow cytometry.
Conclusions: Chemical fingerprinting and structural elucidation confirmed that isolated moiety was camptothecin and it has great potential in treatment of lung and prostate carcinoma as a competent alternative to chemotherapy in the form of herbal medicine.
In-Vitro 3-Dimensional Organoid Models – A Concise Review on Clinical Importance
Authors: Bairagi Ritu , Patil Rupali
Published: April 2024

Organoids are three-dimensional structures that are grown in vitro. Adult stem cells, as well as embryonic stem cells and induced pluripotent stem cells, can be used to make them. To derive these organoids requirements are Tissue and Matrix. The matrix gives support and it should resemble the extracellular matrix for the cells. Microcontact printing and Bioprinting techniques are used for preparing matrices. Many organoids are generated from cells like brain organoids, liver organoids, mammary gland organoids, and some cancer organoids. These Organoid models are used for studying the human-specific disease mechanisms. Due to the specific organoid models, study of many tissues is possible ranging from small intestine, prostate, brain and liver. This review explores the applications of cell-derived organoids, their advantages, and current breakthroughs in organoid models.
PENGGUNAAN MEDIA PEMBELAJARAN BERBASIS APLIKASI (KAHOOT) TERHADAP HASIL BELAJAR PESERTA DIDIK PADA MATA PELAJARAN FIQIH KELAS VII DI MTS MUHAMMADIYAH 06 BANYUTENGAH TAHUN PELAJARAN 2020/2021
Authors: Idzi Layyinnati  , Nisa’atul Wahidah
Published: April 2024

This research is motivated by the increasing development of technologyin the era of the industrial revolution 4.0, educators can innovate learning tomake the learning process more interesting, namely by utilizing various programsthat can produce an interactive learning media. The lack of use of learning mediaused, especially in Fiqh learning, makes students' learning motivation decreaseand feel bored in the learning process which tends to use conventional methods.One of the latest application programs that can be used as interactive learningmedia is the Kahoot educational game application. The purpose of this study is todetermine whether there is an effect of application-based learning media(Kahoot) on student learning outcomes at MTs Muhammadiyah 06 Banyutengah.This study used a quantitative approach with a One-group pretest-posttest designand the number of respondents was 26 respondents, using sample data. Datacollection using pre-test and post-test questions. The collected data were analyzedby validity test, reliability test, normality test, homogeneity test, correlation test,significance test and coefficient of determination. Based on the results ofcalculations obtained manually with hypothesis testing using the product momentcorrelation formula, the results obtained rcount = 0.730> rtable = 0.3882. Whilefor the significance test, the results obtained tcount = 5.228> ttable = 2.063 atthe 5% significance level. From the discussion as mentioned, it can be concludedthat Ho is rejected and Ha is accepted or there is a positive and significantinfluence between Application-Based Learning Media (Kahoot) on StudentLearning Outcomes in Fiqh Class VII Subjects at MTs Muhammadiyah 06Banyutengah 2020/2021 Study Year
Ritual Kaago-Ago Dan Folu Net Sink 2030 Dalam Pengelolaan Lahan Gambut Yang Berkelanjutan Di Desa Marobo Kecamatan Marobo Kabupaten Muna
Authors: Syahrun  , Hasni Hasan  , La Ode Wahidin  , Muh. Husriadi  , Salebaran
Published: April 2024

Ritual kaago-ago merupakan ritual musim tanam yang dilakukan oleh petani padamasyarakat Muna. Desa Marobo sebagai salah satu desa yang masih melaksanakan ritualkaago-ago. Ritual ini masuk dalam kategori warisan tak benda yang masih eksis hinggasekarang. Pelaksanaan ritual kaago-ago yang dimaksudkan ketika memasuki musim tanamagar tanaman dapat tumbuh dengan baik hingga panen. Salah satu nilai kehidupan yangterkandung dalam kaago-ago adalah aspek ekologis. Adapun aspek ekologis dalamkeberlanjutan lingkungan dan hubungan timbal balik. Hubungan ritual kaago-ago dan strategiyang dilakukan menuju Indonesia FOLU Net Sink 2030 agar kontribusi budaya dan mitigasiperubahan iklim melalui pengelolaan hutan dan lahan yang berkelanjutan. Nilai ekologisdalam budaya dimaksudkan sebagai bentuk efisiensi dan kearifan lokal dalam penggunaanlahan. Pengelolaan lahan gambut yang berkelanjutan dengan menggunakan teknikpengelolaan air yang tepat pada lahan gambut dengan membuat saluran air yang dapatdimanfaatkan dengan tujuan pengendalian keberadaan air tanag sesuai dengan kebutuhantanaman. Penggunaan air secara tepat guna dimusim kering (kemarau) namun tidakmengalami genangan pada musim hujan (kelebihan air). Pengelolaan restorasi lahan gambutyang mengalami kerusakan serta memanfaatkan ketersediaan lahan gambut untukkepentingan perkebunan bagi masyarakat sekitar. Adapun dalam penelitian ini diharapkanmampu memberikan edukasi terhadap masyarakat sekitar terkait keberlanjutan lahan gambutdan pengendalian perubagan iklim secara global.
Model Pembelajaran Snowball Throwing Terhadap Peningkatan Hasil Belajar Siswa Mata Pelajaran Pendidikan Agama Islam Kelas VIII SMP
Authors: Layyinnati Idzi , Agustina Susi milad
Published: April 2024

The purpose of this study is: To test whether there are differences in student learning outcomes before using the Snowball Throwing model with the learning outcomes of students who have used the Snowball Throwing model. To find out the effect of the Snowball Throwing learning model on improving student learning outcomes in Islamic Religious Education for class VIII at SMP Muhammadiyah 25 Modern Paciran Lamongan. From the results of data analysis it was found that student learning outcomes had increased. In the Pre-Test questions, the average student score was 74.36 with a classical learning mastery of 51%. In the Post-Test questions, the average score of students increased by 84 with classical learning mastery reaching 85%. Thus it can be said that learning using the Snowball Throwing model can improve student learning outcomes in Islamic Religious Education class VIII at SMP Muhammadiyah 25 Modern Paciran Lamongan..
ANALYSIS OF THE CAPABILITIES OF TOOLS FOR IMPLEMENTING PROCESS MINING TECHNOLOGY
Authors:   Penza State University, Demushkina K.M. , Kuzmin A.V. ,   Penza State University
Published: April 2024

Modern realities dictate the requirements for effective optimization of production. Modernization of business, economics, production, healthcare and medicine in general is an urgent task of our time. One of the technologies for effective process analysis is process mining. Process mining technology allows you to extract knowledge from an event log, forming a process model based on it. Such tools make it possible to identify ineffective management structures and business processes, malfunctions in software, and incompetence of employees, solving many problems of organizing effective management in various industries. Today there are many software tools that implement process analysis methods: Disco, Apromore, ProM. Celonis Process Mining, UiPath Process Mining, etc. Selecting software for certain tasks is a complex process, which subsequently affects the implementation of the project as a whole. Therefore, it is extremely important to comprehensively analyze all the capabilities and limitations of existing process mining tools. The following criteria were selected: cost of the framework; availability of source code; programming language; the ability to build a decision tree based on the process; technical support; technical documentation; developed community of developers; the ability to create and add plugins; experience with the framework. Healthcare was chosen as the target application area. According to the results of the analysis, it was concluded that the use of the ProM framework is effective for solving problems in the field of healthcare.
SIMULATION AND COMPARISON OF THE RESULTS OF THE EXACT ANALYTICAL SOLUTIONOF THE BOUNDARY PROBLEM OF A FLOW IN A THIN LAYER WITH EXPERIMENTAL DATA
Authors:   Moscow State Technological University ", Yanovskaya E.A. ,   STANKIN"
Published: April 2024

The approach under study is important for practical application, since is the basis of many basic plastic deformation operations associated with plastic flow in a thin layer of material deformed by rolls (longitudinal rolling, rolling) or dies (volumetric and sheet stamping), which are described by spatial mathematical models with a variety of parameters that determine the rheology of the material. Pressures are created on the contact surfaces of the processing material with the tool, which exceed the shear characteristics of the material by an order of magnitude, so that, in the initial approximation, it is possible to use the model of a hydrodynamic fluid to describe the properties of the material of the plastic layer [1, 2, 3]. As was shown earlier, sliding is observed almost along the entire contact surface, in which the contact surfaces coincide with the sliding surfaces, and the specific friction forces on them are maximum [4] and equal to the shear yield strength of the material [5, 6]. It should be noted another feature of the course of these processes, which determines the requirements for the accuracy of the final forging. It is clear that high contact pressures cause normal elastic displacements of the working surfaces of the tool, commensurate with the thickness of the plastic layer [7, 8]. We consider a plastic layer in the wedge-shaped region, composed of materials with different mechanical characteristics. the layer spreads freely between the rigid rough slabs converging in parallel. The layer under the action in the direction of the thickness of the distributed load from the side of the tool flows freely in the direction of the radii.
USE OF CHARACTERISTICS IN NON-STATIONARY PROBLEMS OF PLASTIC FLOW OF A THIN LAYER ALONG PLANES
Authors:   Moscow State Technological University ", Yanovskaya E.A. ,   STANKIN"
Published: April 2024

The calculations are based on the proposed Ilyushin A.A. [1] theory of flow in a thin plastic layer enclosed between two surfaces of tool bodies approaching each other according to a given law. On contact surfaces, the classical L. Prandtl flow law is adopted [2]. To solve the proposed problem, the well-known boundary value problem in the formulation of the "ideal fluid" is used. This setting is described by nonlinear differential equations in partial derivatives of the first order with respect to the contact pressure and components of the flow velocity vector along the flow plane [3, 4]. In the general case, the desired values are complex functions that depend on the shape of the deformation zone, the value of the contact pressure at the considered point of the contact surface, the presence, composition and degree of lubrication, the roughness of the contacting surfaces, etc. [5, 6]. The paper proposes a method for solving problems of the flow of plastic layers in a new formulation. The analysis of the received result is carried out. Based on the method of characteristics, the problem of the flow of a plastic layer of material between inclined plates in a fixed circular area is solved, when its boundary is formed by grooves in one of the tool bodies, where the plastic material flows freely. Using the proposed solution, it is possible to construct the kinematics of the flow.
RISK MANAGEMENT OF CUSTOM SMALL-SCALE PRODUCTION
Authors:   Samara National Research University named after academician S.P. Korolyov, Koleganova E.A. , Khaimovich A.I. ,   Samara National Research University named after academician S.P. Korolyov, Kovaleva A.M. ,   Samara National Research University named after academician S.P. Korolyov
Published: April 2024

The article discusses the method for assessing production risks using simulation modeling. A loading model for small-scale production has been developed, taking into account its features. The risks were assessed, their interrelation and influence on the time of production processes were revealed.
Performance Analysis of Grid Configuration Wireless Sensor Network using Different Packet Frequency for Oil and Gas Downstream Pipeline
Authors: Vijayakumaran Thinesh , Subramaniam Siva Kumar , Feroz Farah Shahnaz , Sujatha R.
Published: April 2024

Over the most recent few years, there has been a shift away from utilizing costly links to communicate information from different sensors, including those estimating wind, vibration, temperature, and stickiness, to observing locales. This progress has been worked with by the reception of Wireless sensor networks (WSNs), which proposition expanded adaptability and more extensive inclusion capacities. In different businesses, these organizations have acquired ubiquity because of their flexibility. In particular, with regards to observing oil and gas offices, framework-based WSNs demonstrate profoundly appropriate for covering broad regions, especially inside the downstream period of the oil and gas handling chain. The essential point of this examination is to research how different bundle frequencies, the quantity of nodes, and directing conventions influence a lattice-based WSN. The review presents two sorts of steering conventions: responsive (AODV) and proactive (OLSR), utilizing a lattice hub plan and trying different things with different bundle frequencies. The reenactment results uncover that as the bundle recurrence builds, there is a perceptible decrease in execution, no matter what the organization's size. This presentation decline is clear in measurements like the conveyance proportion, network reasonableness, and the presence of aloof nodes inside the organization, particularly while sending 80 nodes or more. Moreover, it's significant that the AODV steering convention outflanks the OLSR partner concerning throughput, conveyance proportion, and the presence of passive nodes.
Comprehension and understanding of the book
“It was forever until it was over.
The last Soviet generation”
Authors: Rozin Vadim
Published: April 2024

The article discusses the book by A. Yurchak, in which he offers a scientific explanation of the causes and process of the completion of socialist culture and the death of the USSR. The author analyzes the central concept used in this explanation — “authoritative discourse”, showing that the latter is interpreted in two ways: within the framework of the semiotic approach outlined by John Austin, and the “dispositive” approach developed by Michel Foucault. Based on the analysis of the case from the book, the author offers his own reconstruction and concepts (“schemas”, “life world”, “sociality”) that can complement Yurchak’s research. A comparison of the latter’s explanation and the explanation of sociologist Leonid Ionin, carried out during the period of perestroika and reforms, made it possible to clarify Yurchak’s approach and methodology.
Клинический случай гиперандрогении у пациентки с болезнью Иценко-Кушинга
Authors: Бакиржан М.А. , Кожемжарова М.К. , Куанышбаева Г.С. , Досжанова Г.Н. , Каркабаева А.Д.
Published: April 2024

Актуальность: Синдром гиперандрогении (СГА) представляет собой группу эндокринных нарушений, характеризующихся увеличенным уровнем мужских гормонов (андрогенов) у женщин. СГА имеет большую социально-общественную значимость. Актуальность изучения СГА определяется рядом факторов: большой распространенностью (свыше 10% в женской популяции), значимым влиянием на качество жизни, связью с эндокринной формой бесплодия, а также высокой частотой сопутствующих метаболических заболеваний (ожирение, сахарный диабет типа 2, атеросклероз). Клинические проявления гиперандрогенизма включают гирсутизм, себорею, акне, андрогенную алопецию и вирилизацию.Цель исследования – рассмотреть дифференциальную диагностику гиперандрогенных состояний при различных эндокринопатиях на примере клинического случая СГА у пациентки с болезнью Иценко-Кушинга.Материалы и методы: В данной статье рассмотрен клинический случай СГА у пациентки с болезнью Иценко-Кушинга. Пациентка обратилась к врачу косметологу с жалобами на акне, гирсутизм и прибавку в весе на 20 кг. Появление симптомов значительно повлияло на психологическое состояние пациентки, так как до болезни девушка работала моделью. В связи с неэффективностью медикаментозной терапии, а также различных косметологических манипуляций и добавлением таких симптомов, как одутловатость лица, жировые отложения на шее и плечах, растяжки в подмышечной области, была направлена к эндокринологу.Результаты: В ходе дифференциальной диагностики, учитывая синдром гиперандрогении и опираясь на клинические признаки гиперкортизолизма, пациентке была диагностирована болезнь Иценко-Кушинга.Заключение: Так как фенотип данного синдрома достаточно обширный и встречаемость акне превышает встречаемость гирсутизма, пациенты могут долгое время лечиться только у косметолога или дерматолога. Точная и структурированная диагностика позволяет избежать задержки в установлении правильного диагноза и начать целенаправленное лечение, а также предупредить возможные осложнения. Индивидуализированный подход к СГА играет ключевую роль в обеспечении оптимального клинического и психологического исхода для пациентов.
Анализ причин преждевременных родов
Authors: Садуакасова Ш.М. , Базарбаева Ж.У. , Айгырбаева А.Н. , Бузумова Ж.О. , Алмасбек А.А. , Курбанбай А.Б. , Жолбарыс Д.А. , Примбетова А.Ш. , Толеубаева А.А.
Published: April 2024

Актуальность: Преждевременные роды являются одной из наиболее актуальных проблем современной медицины и определяются как многофакторный процесс, имеющий множество причин и осложнений, включая осложнения со стороны матери или плода, требующие медицинского вмешательства. Из всех живорождений в мире 11% являются преждевременными, тогда как у женщин с предлежанием плаценты или низкой плацентацией этот риск увеличивается в 2-4 раза.Цель исследования – проанализировать причины и определить наиболее частые факторы риска преждевременных родов.Материалы и методы: Нами было обследовано 66 женщин репродуктивного возраста с преждевременными родами (основная группа) и 60 женщин, родившие в срок (контрольная группа). Это было сравнительное ретроспективное исследование на базе городской поликлиники №36 г. Алматы, проводившееся с января по ноябрь 2023 года. Нами было проанализированы индивидуальные карты беременных с 6 недель беременности. Беременные и родильницы, вошедшие в исследование были идентифицированы по кодам Международной классификации болезней (МКБ) и внесены в систему электронной медицинской документации Damumed.Результаты: В статье представлены результаты ретроспективного и проспективного исследования беременных с преждевременными родами. В результате анализа акушерского анамнеза было выявлено, что 20 женщин (30,3%) были перводящими, 18 (27,27%) женщин были многорожавшими. При изучении анамнеза женщин с преждевременными родами было обнаружено, что во время предыдущих беременностей эпизоды бессимптомной бактериурии отмечались у 9 (13,64%) женщин, а во время данной беременности бессимптомная бактериурия была диагностирована в 21 (31,82%) случаях.Заключение: По результатам нашего исследования выявлена весьма высокая взаимосвязь между инфекциями мочеполового тракта и риском развития преждевременных родов. Сопутствующими факторами риска преждевременных родов были возраст матери старше 35 лет, гипертензивные состояния во время беременности и преждевременный разрыв плодных оболочек.
Влияние материнского микробиома на развитие преэклампсии: обзор литературы
Authors: Сафарова К.Т. , Омертаева Д.Е. , Мугазов М.М. , Амирбекова Ж.Т. , Увашева А.Д. , Акжол Г.А.
Published: April 2024

Актуальность: Преэклампсия является ведущей причиной материнской и перинатальной заболеваемости и смертности во всем мире. Преэклампсия – это гипертензивное заболевание беременных. Данный тяжёлый вариант гестоза возникает после 20-й недели, связан с ангиогенным дисбалансом, эндотелиальной дисфункцией матери и повреждением органов-мишеней и характеризуется полиорганными нарушениями. В отношении плода, ограничивается его рост. Известно, что микробиота является основным фактором в поддержании гомеостаза организма человека. На неё возложены значимые функции энергетического обмена, созревания и поддержания иммунной системы, синтеза витаминов, регуляции обратного всасывания в кишечнике желчных кислот и многое другое.Цель исследования – определить диагностическую значимость микробиоты кишечника при преэклампсии и ее связи с преэклампсией.Материалы и методы: Был проведен поиск исследований в двух электронных базах данных (PubMed и Web of Science), включенных в период с 2012 по 2023 год. Проанализировано 37 статей зарубежной литературы. Ключевыми словами при поиске в базах данных были: «microbiome AND preeclampsia», «microbiome AND pregnancy complications».Результаты: Была отмечена схожесть результатов проводимых исследований, однако были обнаружены и неоднозначные результаты, что, безусловно, требует дальнейшего изучения. Было доказано, что под воздействием внешних факторов условно-патогенная микрофлора способствует развитию многочисленных заболеваний. Однако роль микробиоты до конца так и не изучена, что обусловлено множеством факторов, начиная от количества исследований и их участников, и до вопросов этического характера.Заключение: Открытым остается вопрос, является ли причиной возникновения преэклампсии «инфекционное бремя» либо же воздействие какого-то определенного, на данный момент неизвестного, микроорганизма. Актуальность изучения преэклампсии бесспорна и требует поиска новых подходов с целью управления возникновением и течением данного заболевания, а также поиска новых возможностей для его профилактики.
Особенности влияния синдрома поликистозных яичников на психосоматическое состояние женщин
Authors: Амирбекова Ж.Т. , Панькова А.Н. , Мейрамова Т.К. , Мурзашева Г.К.
Published: April 2024

Актуальность: Синдром поликистозных яичников (СПКЯ) представляет собой сложное репродуктивно-метаболическое заболевание, влияющие на различные аспекты фертильности. У большинства женщин фертильного возраста с СПКЯ диагностируется ожирение, которое усугубляет клинические проявления СПКЯ, ускоряет его манифестацию и в значительной степени способствует развитию осложнений. Известно, что у пациенток с ожирением в сочетании с СПКЯ, статистически значимо чаще выявляются артериальная гипертензия и метаболические нарушения: дислипидемия, висцеральное ожирение, инсулинорезистентность, гиперинсулинемия, гиперурикемия, что суммарно увеличивает кардиоваскулярный риск. Факторы, влияющие на течение СПКЯ, до сих пор остаются предметом исследований.Цель исследования – изучение особенностей влияния СПКЯ на психосоматическое состояние женщин, связи СПКЯ с ожирением, гиперплазией эндометрия, исходами беременности, кардиоваскулярными рисками.Материалы и методы: В рамках изучения литературных данных проводился обзор научных исследований, опубликованных в базах Cochrane, CyberLeninka, PubMed. Глубина поиска – 10 лет (2013-2023 гг.). Нами было изучено 116 статей, из них включены в анализ 15 полнотекстовых статей. Критерии включения: полнотекстовые статьи, поисковые запросы и глубина поиска соответствовала требованиям. Критерии исключения: не имеет отношения к теме исследования, дублирующие публикации, не соответствует поисковым запросам.Результаты: В данном литературном обзоре представлена информация, что СПКЯ выступает как фактор риска развития бесплодия, андрогензависимой дермопатии, нарушений углеводного обмена, включая сахарный диабет 2 типа, дислипидемий, сердечно-сосудистых патологий, высокого уровня самопроизвольных абортов, гиперпластических процессов эндометрия, нарушений психологического статуса – депрессий, тревожных расстройств, а также онкологических заболеваний.
Заключение: У женщин фертильного возраста СПКЯ ассоциируется с более высоким риском бесплодия и кардиометаболических факторов риска, которые связаны с большей распространенностью избыточного веса и ожирения. Женщины с СПКЯ подвергаются более высокому риску осложнений во время беременности и родов, которые усугубляются ожирением до зачатия, гиперандрогенией, вероятностью более высокой прибавки веса во время беременности.
Packaging Sostenible para Productos de Cerámica Realizados por Mujeres Artesanas del Pueblo Shuar en Macas
Authors: Carpio Padilla Patricio Ismael
Published: April 2024

La Fundación Atasim ubicada en Macas, Morona Santiago, ha manifestado su interés en el apoyo en áreas de diseño para los productos artesanales para su proyecto Atasim Artisan.  El CIDAP en conjunto con la Universidad de Cuenca han visto pertinente generar una propuesta de formación acorde a las necesidades e intereses de la fundación. Por lo que a través de un proyecto de vinculación con la sociedad se ha propuesto la construcción de una marca y el diseño de packaging sostenible elaborado con materiales propios de la zona, para que sean aplicados a los productos artesanales de cerámica como máscaras, macetas y joyería. Al final, se desarrollaron talleres de capacitación para que las artesanas puedan elaborar por su cuenta los packagings y adaptar a sus productos cerámicos diseñados. Este proyecto fue elaborado con la participación de ocho estudiantes de la Universidad de Cuenca, la colaboración del equipo técnico del CIDAP y la participación de las artesanas del Pueblo Shuar que forman parte de la Fundación Atasim.
El Curriculo un Factor de Calidad Educativo en la Unidad Educativa San Andrés de la Provincia de Chimborazo
Authors: Paz Sánchez Danilo Gabriel , Lema Guamán Deysi Patricia , Guachi Díaz Maricela Elizabeth , Robalino Zambrano José Andrés , Jara Silva Mery Verónica
Published: April 2024

El aprendizaje de los educandos se ve afectado por falta de capacitación de los docentes para crear un diseño curricular que ayude a mejorar el rendimiento académico. Este trabajo tiene por objetivo determinar el diseño curricular como factor de calidad educativa. La metodología es cuantitativa ya que se utiliza la recolección de datos con base al análisis estadístico, la finalidad es reconocer al diseño curricular como factor de calidad educativa. Los resultados muestran que el 75% de docentes consideran que no es necesario el diseño curricular para mejorar la calidad educativa, por lo que solo emplean la enseñanza tradicional, debido a la falta de conocimiento sobre el diseño curricular y sus beneficios frente al rendimiento académico. Es decir solo el 25% creen conveniente el uso del diseño curricular en la educación, sin embargo, tienen poco conocimiento en la elaboración de este. Concluyendo que el diseño curricular es fundamental siempre y cuando se actualicen los docentes.
Contexto de la Aplicación de la Ley N° 6103 sobre Personas que Presentan Trastornos del Espectro Autista (TEA) y la Gestión Escolar para una Educación Inclusiva, Paraguay
Authors: Velazco Mareco Rocio Elizabeth
Published: April 2024

Definitivamente las personas con Trastorno del Espectro Autista (TEA) se encuentran en una situación de vulnerabilidad social y requieren de mayor acompañamiento para su incorporación, específicamente en el ámbito educativo. Para este trabajo se planteó la hipótesis de dificultades para una gestión escolar eficiente condicionada por una falta de apoyo de la Ley 6103 de Paraguay en cuanto a disponibilidad de recursos tanto financieros como humanos capacitados. La investigación fue bibliográfica, se procedió a la revisión de artículos de diversos autores sobre el tema accediendo a ellos por medio de Google Académico y por el portal CICCO de CONACYT Paraguay, con materiales de los años 2000 al 2016 y 2018 al 2022. La conclusión es que existe la Ley N° 6103 que establece responsables y acciones que pueden ser realizadas por instituciones gubernamentales, sin embargo, carecen de mecanismos de seguimiento sobre su implementación efectiva. En cuanto a la gestión escolar requiere de un involucramiento integral de todo el estamento educativo, directivo; acompañamiento a los docentes y sobre todo con capacitaciones de los mismos y la intervención de profesionales para lo cual la política Ministerio de Educación y Ciencias debe ser analizado con detenimiento.
El Desarrollo de la Autonomía en el Proceso de Aprendizaje de Lenguas Extranjeras: Uso del m-Learning Mediante la Aplicación Tándem
Authors: Rodríguez Flores Juan Carlos
Published: April 2024

Este estudio profundiza en el ámbito del desarrollo de la autonomía en el proceso de aprendizaje de lenguas extranjeras, con un enfoque específico en aprovechar el aprendizaje móvil (m-learning) a través de la aplicación móvil Tandem. La investigación plantea el impacto del uso de Tandem como una herramienta para mejorar la autonomía de los estudiantes en el proceso de adquisición de idiomas.  El estudio emplea un enfoque de métodos mixtos, que combina datos cuantitativos de las interacciones de los usuarios dentro de la aplicación Tandem con información cualitativa recopilada a través de encuestas. A través de este análisis, la investigación pretende dilucidar el papel del m-learning en el fomento de la autonomía, explorando las formas en que los estudiantes toman el control del aprendizaje de idiomas a través de la plataforma Tandem y el método de estudio con el mismo nombre. Los hallazgos contribuyen a la comprensión de los beneficios y desafíos potenciales asociados con la integración de aplicaciones móviles como Tandem en la educación lingüística. La información obtenida de esta investigación puede informar a los educadores, desarrolladores de aplicaciones y estudiantes de idiomas sobre estrategias eficaces para promover la autonomía en el cambiante panorama del aprendizaje de idiomas, con especial énfasis en el entorno de aprendizaje móvil.
The Impact of the Logotherapy-Based Spiritually Oriented Group Counseling on Meaning in Life and Multi-Measure Agentic Personality Levels of Emerging Adults
Authors: Yıldız Hatice Vildan
Published: April 2024

In this study, it was aimed to examine the effectiveness of the 8-session group psychological counseling based on logotherapy, which was developed to increase the level of meaning in life and active personality traits of emerging adults. This research employed a pre-test, post-test, control group experimental design and was conducted online on emerging adults. The experimental group and the research control group were formed with 10 participants among the emerging adults who voluntarily agreed to participate in the research. The study group consisted of 20 emerging adults, aged 18-25; 10 (3 men, 7 women) were in the experimental group, and 10 (4 men, 6 women) were in the control group. Purpose in Life Scale and Multi-Measure Agentic Personality Scale were applied to the experimental and control groups as pre-test and post-test. The experimental group of 10 participants received around 90 minutes of 8 sessions of logotherapy-based, spiritually oriented group counseling; however, no such application was made to the control group. The nonparametric Mann Whitney U test was conducted to determine whether the scores of the experimental and control groups on the multi-measure agentic personality and life purpose scales changed significantly between the pre- and post-tests. The non-parametric Wilcoxon Signed Ranks test was applied to determine whether there was a significant difference between the experimental and control groups’ life purpose, multi-measure agentic personality scale post-test scores, and pre-test scores. The practice of spiritually oriented group counseling based on logotherapy was found to be statistically significant at the levels of finding the meaning in life and multi measure agentic personality traits, and the findings were analyzed in the context of the literature. This study tested the efficacy of this program, and it reveals the findings on emerging adults that professionals studying in various disciplines could use this program in a functional way in their studies.
Social Impact Assessment of Urban Mass Transit: A Case Study of Metro Rail in India
Authors: K. Pradhan Sanjay
Published: April 2024

The country's efforts to improve its infrastructure are important for promoting economic growth and alleviating poverty. However, these initiatives often result in negative consequences alongside their positive outcomes. These negative effects can manifest in various forms, including social, cultural, economic, and environmental impacts. As such, it is imperative to anticipate and prevent these undesirable outcomes to achieve inclusive and sustainable development. The importance of Social Impact Assessment (SIA) and meaningful public consultation in infrastructure projects has been recognized by social scientists, policymakers, international financial institutions, and development practitioners as effective measures to mitigate adverse social impacts of development projects. This is equally applicable to urban transportation projects, which also require a thorough evaluation of their social impacts. In this paper, we examine the SIA rules and regulations under the RFCTLARR Act 2013, assess the social impacts of the Ahmedabad metro rail project (Phase-I), and propose mitigation measures to minimize negative impacts and maximize positive ones for all stakeholders involved. It is argued that addressing social issues early in the project and integrating them into resettlement management can greatly increase the chances of project success.