bluuebunny/crossref_metadata_2025 huggingface dataset:
Hovenia dulcis Fruit Peduncle Polysaccharides Reduce Intestinal Dysbiosis and Hepatic Fatty Acid Metabolism Disorders in Alcohol-Exposed Mice
Authors: Liu Liangyu , Zhu Sijie , Zhang Yuchao , Zhu Zhenyuan , Xue Yong , Liu Xudong
Published: April 2024

Alcohol abuse can lead to alcoholic liver disease, becoming a major global burden. Hovenia dulcis fruit peduncle polysaccharides (HDPs) have the potential to alleviate alcoholic liver injury and play essential roles in treating alcohol-exposed liver disease; however, the hepatoprotective effects and mechanisms remain elusive. In this study, we investigated the hepatoprotective effects of HDPs and their potential mechanisms in alcohol-exposed mice through liver metabolomics and gut microbiome. The results found that HDPs reduced medium-dose alcohol-caused dyslipidemia (significantly elevated T-CHO, TG, LDL-C), elevated liver glycogen levels, and inhibited intestinal-hepatic inflammation (significantly decreased IL-4, IFN-γ and TNF-α), consequently reversing hepatic pathological changes. When applying gut microbiome analysis, HDPs showed significant decreases in Proteobacteria, significant increases in Firmicutes at the phylum level, increased Lactobacillus abundance, and decreased Enterobacteria abundance, maintaining the composition of gut microbiota. Further hepatic metabolomics analysis revealed that HDPs had a regulatory effect on hepatic fatty acid metabolism, by increasing the major metabolic pathways including arachidonic acid and glycerophospholipid metabolism, and identified two important metabolites—C00157 (phosphatidylcholine, a glycerophospholipid plays a central role in energy production) and C04230 (1-Acyl-sn-glycero-3-phosphocholine, a lysophospholipid involved in the breakdown of phospholipids)—involved in the above metabolism. Overall, HDPs reduced intestinal dysbiosis and hepatic fatty acid metabolism disorders in alcohol-exposed mice, suggesting that HDPs have a beneficial effect on alleviating alcohol-induced hepatic metabolic disorders.
Prehistoric and Early Roman Period Goldwork from Northwestern Iberia: An Analytical Study of Artefacts from the Archaeological and Historical Museum of A Coruña
Authors: García-Vuelta Óscar , Armada Xosé-Lois
Published: April 2024

This article presents the results of a topographical and analytical study using hh-XRF of 22 gold and gilded objects from the Archaeological and Historical Museum of A Coruña (Galicia, Spain). They are highly representative of the northwestern Iberian goldwork from the Chalcolithic (third millennium BC) to the early Roman period (first century AD). This study contributes to our knowledge of the production techniques used in those periods, as well as their evolution over time. The collection includes some of the most representative types in this area, such as Early Bronze Age “sheet collars” and torcs from the Second Iron Age. In the case of torcs, new data are provided on one of the formally best-documented types (the Artabrian type) and on those known as “Baroque torcs” that are characteristic of the final moments of this goldsmith tradition. While pieces from the Chalcolithic and Early Bronze Age were made with alluvial gold, the torcs from the Late Iron Age contain variable amounts of silver and copper. Also detected is the frequent use of cores made of less precious metals, which were subsequently given a golden appearance using gilding techniques. The new data are discussed in light of our current knowledge of NW Iberian goldwork, one of the most representative of this craft tradition in Western Europe for those periods.
Mapmaking Process Reading from Local Distortions in Historical Maps: A Geographically Weighted Bidimensional Regression Analysis of a Japanese Castle Map
Authors: Yabe Naoto
Published: April 2024

Shoho Castle Maps are maps of castle towns throughout Japan drawn by Kano School painters on the order of the shogun in 1644. The Shoho Castle Map of Takada, Joetsu City, Niigata Prefecture was used to visualize local distortions in historical maps and to scrutinize the mapmaking process. A novel method, geographically weighted bidimensional regression, was developed and applied to visualize the local distortions of the map. Exaggerated expressions by mapmakers that have not been identified in previous studies were revealed. That is, in addition to the castle being drawn enlarged, the town where the merchants and artisans lived was drawn larger than the castle. Therefore, the Takada Shoho Castle Map reflects mapmakers’ intentions, besides enlarging military facilities, which appear to have emphasized the pictorial composition of the map by placing the main gate to the castle at the center and drawing the map area evenly from the center in a well-balanced layout.
Bioactive Compounds Formulated in Phytosomes Administered as Complementary Therapy for Metabolic Disorders
Authors: Toma Laura , Deleanu Mariana , Sanda Gabriela Maria , Barbălată Teodora , Niculescu Loredan Ştefan , Sima Anca Volumnia , Stancu Camelia Sorina
Published: April 2024

Metabolic disorders (MDs), including dyslipidemia, non-alcoholic fatty liver disease, diabetes mellitus, obesity and cardiovascular diseases are a significant threat to human health, despite the many therapies developed for their treatment. Different classes of bioactive compounds, such as polyphenols, flavonoids, alkaloids, and triterpenes have shown therapeutic potential in ameliorating various disorders. Most of these compounds present low bioavailability when administered orally, being rapidly metabolized in the digestive tract and liver which makes their metabolites less effective. Moreover, some of the bioactive compounds cannot fully exert their beneficial properties due to the low solubility and complex chemical structure which impede the passive diffusion through the intestinal cell membranes. To overcome these limitations, an innovative delivery system of phytosomes was developed. This review aims to highlight the scientific evidence proving the enhanced therapeutic benefits of the bioactive compounds formulated in phytosomes compared to the free compounds. The existing knowledge concerning the phytosomes’ preparation, their characterization and bioavailability as well as the commercially available phytosomes with therapeutic potential to alleviate MDs are concisely depicted. This review brings arguments to encourage the use of phytosome formulation to diminish risk factors inducing MDs, or to treat the already installed diseases as complementary therapy to allopathic medication.
Students’ Experiences with Interprofessional Service-Learning Global Health Education Pilot Program in Ghana
Authors: Anafi Patricia , Meckel Marie , Peterson Lori Jean
Published: April 2024

Interprofessional service-learning programs can help to break down the education and training silos between public health and health care in the United States. This paper describes the development and implementation of one such program between the University of Massachusetts, Amherst, School of Public Health and Health Sciences, Bay Path University Physician Assistant Program, and the Wa-West Health District in Ghana. The program brought together Master of Public Health students and Physician Assistant students to complete an applied practicum and training experience in a low-resource community that faces significant health care and public health delivery challenges. In 2017 and 2018, nine students participated in the two-year pilot program, UMass Amherst Interprofessional Integrated Service Learning and Community-Based Participatory Collaboration. Students completed projects designed by Ghanaian health officials over two summers in direct collaboration with the communities. Findings from the evaluation of the pilot program revealed that though the students faced some challenges with the program, such as language barriers, transportation issues due to poor roads, and difficulty scheduling meetings while completing their projects in Ghana, the majority described their experience as positive and were satisfied. Some expressed the idea that their experiences were something that they could incorporate into their current and future practices. In addition, they reported that interprofessional communications and collaborations were effective. Recommendations are offered to address the program’s challenges for its continuation and formalization.
Evolution of Minimally Invasive and Non-Invasive Preimplantation Genetic Testing: An Overview
Authors: Moustakli Efthalia , Zikopoulos Athanasios , Skentou Charikleia , Bouba Ioanna , Dafopoulos Konstantinos , Georgiou Ioannis
Published: April 2024

Preimplantation genetic testing (PGT) has become a common supplementary diagnοstic/testing tοol for in vitro fertilization (ΙVF) cycles due to a significant increase in cases of PGT fοr mοnogenic cοnditions (ΡGT-M) and de novο aneuplοidies (ΡGT-A) over the last ten years. This tendency is mostly attributable to the advancement and application of novel cytogenetic and molecular techniques in clinical practice that are capable of providing an efficient evaluation of the embryonic chromosomal complement and leading to better IVF/ICSI results. Although PGT is widely used, it requires invasive biopsy of the blastocyst, which may harm the embryo. Non-invasive approaches, like cell-free DNA (cfDNA) testing, have lower risks but have drawbacks in consistency and sensitivity. This review discusses new developments and opportunities in the field of preimplantation genetic testing, enhancing the overall effectiveness and accessibility of preimplantation testing in the framework of developments in genomic sequencing, bioinformatics, and the integration of artificial intelligence in the interpretation of genetic data.
Trustworthiness of Situational Awareness: Significance and Quantification
Authors: Munir Arslan , Aved Alexander , Pham Khanh , Kong Joonho
Published: April 2024

Situational awareness (SA) is of tremendous significance for successful operations in many domains, such as surveillance, humanitarian, search, and rescue missions, and national security. SA is particularly important for the defense sector, and is regarded as the decisive factor in military and air combat engagements. Commanders and operators rely on the accuracy and fidelity of SA for comprehending the environment, decision-making, and carrying out actions based on these decisions for accomplishing a mission. SA, however, is susceptible to adversarial attacks that can compromise the security and trust of SA systems. In this paper, we discuss the significance of security and trust of SA from an air force perspective. We then propose a model for quantifying the trustworthiness of an SA system. We further present numerical examples that demonstrate the quantification of trustworthiness of an SA system using our proposed model. Finally, we conclude this paper with future research directions for quantifying the security of SA systems.
Data-Driven Network Anomaly Detection with Cyber Attack and Defense Visualization
Authors: Muhati Eric , Rawat Danda
Published: April 2024

The exponential growth in data volumes, combined with the inherent complexity of network algorithms, has drastically affected network security. Data activities are producing voluminous network logs that often mask critical vulnerabilities. Although there are efforts to address these hidden vulnerabilities, the solutions often come at high costs or increased complexities. In contrast, the potential of open-source tools, recognized for their security analysis capabilities, remains under-researched. These tools have the potential for detailed extraction of essential network components, and they strengthen network security. Addressing this gap, our paper proposes a data analytics-driven network anomaly detection model, which is uniquely complemented with a visualization layer, making the dynamics of cyberattacks and their subsequent defenses distinctive in near real-time. Our novel approach, based on network scanning tools and network discovery services, allows us to visualize the network based on how many IP-based networking devices are live, then we implement a data analytics-based intrusion detection system that scrutinizes all network connections. We then initiate mitigation measures, visually distinguishing malicious from benign connections using red and blue hues, respectively. Our experimental evaluation shows an F1 score of 97.9% and a minimal false positive rate of 0.3% in our model, demonstrating a marked improvement over existing research in this domain.
Tailoring Basalt Fibers and E-Glass Fibers as Reinforcements for Increased Impact Resistance
Authors: Natarajan Elango , Mozhuguan Sekar Santhosh , Markandan Kalaimani , Ang Chun Kit , Franz Gérald
Published: April 2024

The usage of basalt fiber in the engineering industries has gained significant interest due to its characteristics such as alkali resistance and enhanced mechanical properties. Similarly, E-glass-fiber-reinforced composites have been widely used in the fabrication of electrically resistive industrial components such as switches, circuit panels, and covering cases. In the present study, the tensile, flexural, thermogravimetric, and low-velocity impact characteristics of various percentages of basalt/E-glass-fiber-reinforced polymer composites fabricated via vacuum-assisted resin transfer molding were investigated. The results show that a higher volume percentage of basalt (39%) significantly enhances the impact resistance up to 45% with a moderate improvement in flexural properties. The higher the vol % of E-glass (40%), the more the tensile and flexural properties are increased, i.e., 185 N/mm2 and 227.87 N/mm2, respectively. It is concluded that by choosing the optimum hybridization method, impact resistance and other mechanical properties can be improved significantly. The thermogravimetric analysis results show that PC313534 (35 vol % basalt and 34 vol % E-glass) possesses the lowest decomposition temperature of 381.10 °C. The results from the present study indicate that the polymer composite fabricated in the present study is suitable for applications where higher structural-load-resistive properties are required.
Assessing the Digital Transformation in the Maritime Transport Sector: A Case Study of Croatia
Authors: Jović Marija , Tijan Edvard , Aksentijević Saša , Pucihar Andreja
Published: April 2024

In this research, the authors investigated the factors of digital transformation in the maritime transport sector, which were applied to the case study of Croatia. Since there is a pronounced lack of research dealing with the digital transformation factors in the maritime transport sector both globally and in Croatia, as a first step the authors identified the aforementioned factors using the literature review method and interviews. Moreover, the survey was carried out among a representative group of stakeholders involved in the maritime transport sector in Croatia, including administrative entities such as port authorities, ministries, and harbormaster’s offices, as well as commercial participants such as freight forwarders, agents, and terminal operators. The goal was to obtain the state of the art of digital transformation in the maritime transport sector. A total of 94 organizations provided valid responses. Finally, the authors proposed measures to improve the digital transformation in the maritime transport sector in Croatia. The results highlighted the importance of various digital transformation factors, such as information security, investment in emerging technologies, leadership motivation, and expertise. The case study presented serves as a valuable reference for comparable countries that recognize their resource constraints but aspire to enhance their efficiency and competitiveness.
Combating Hate Speech on Social Media: Applying Targeted Regulation, Developing Civil-Communicative Skills and Utilising Local Evidence-Based Anti-Hate Speech Interventions
Authors: Pukallus Stefanie , Arthur Catherine
Published: April 2024

Social media platforms such as Facebook and X (formerly Twitter) set their core aim as bringing people and communities closer together. Yet, they resemble a digital communicative battleground in which hate speech is increasingly present. Hate speech is not benign. It is the communicative driver of group oppression. It is therefore imperative to disarm this digital communicative battlefield by (a) regulating and redesigning social media platforms to prevent them from playing an active and enabling role in the dissemination of hate speech and (b) empowering citizen-users and local civil associations to recognise and actively counter hate speech. This top-down and bottom-up approach necessarily enforces responsibility and builds capacity. This requires that we adapt and combine three aspects of communicative peacebuilding: first, the (re)building of civil-communicative institutions; second, the use of digital citizenship educational programmes to support the development of civil-communicative skills for using social media; and third, the identification and use of local civil capacity and knowledge, which manifests in the present context in the use of local evidence-based anti-hate speech interventions. We argue that this interdisciplinary combinatorial approach has the potential to be effective because it combines two things: it places responsibility on relevant actors to both make social media safer and to navigate it harmlessly and responsibly; and it simultaneously helps build the capacity for actively identifying and countering hate speech in civil societies.
An Active Approach for Teaching and Learning Electrical Technology
Authors: Terron-Santiago Carla , Burriel-Valencia Jordi , Martinez-Roman Javier , Sapena-Bano Angel
Published: April 2024

This contribution describes the change in methodology introduced in the subject of electrical technology within the industrial technologies engineering degree at Escuela Técnica Superior de Ingeniería Industrial, Universitat Politècnica de València. The main purpose of the methodology change was to improve the attainment of student outcomes by the introduction of project-based learning supported by flipped teaching. Moreover, a software tool was developed that generates standard exercise statements for the design of electrical installations. Using this tool, students can practice with different problem exercises, enter their solution, and receive immediate feedback on their results, improving the teaching–learning experience. The level of student outcomes attained was improved, and other positive aspects arose from the experience, such as boosting students’ responsibility in their own learning (learn to learn), their ability to solve problems, and students’ motivation. Furthermore, the instructors’ opinions on the methodology change were highly positive.
Correction: Săgeată et al. Deindustrialization, Tertiarization and Suburbanization in Central and Eastern Europe. Lessons Learned from Bucharest City, Romania. Land 2023, 12, 1731
Authors: Săgeată Radu , Mitrică Bianca , Cercleux Andreea-Loreta , Grigorescu Ines , Hardi Tamás
Published: April 2024

In the original publication [...]
Performance of a Set of Soil Water Retention Models for Fitting Soil Water Retention Data Covering All Textural Classes
Authors: Rasoulzadeh Ali , Bezaatpour Javad , Mobaser Javanshir Azizi , Fernández-Gálvez Jesús
Published: April 2024

A clean environment is an essential component of sustainable development, which is based on a comprehensive understanding of the behavior of water, soil, and air. The soil water retention (SWR) curve is a crucial function that describes how soil retains water, playing a fundamental role in irrigation and drainage, soil conservation, as well as water and contaminant transport in the vadose zone. This study evaluates the accuracy, performance, and prediction capabilities of 15 SWR models. A total of 140 soil samples were collected from different sites, covering all textural classes. Standard suction tests, using both hanging column and ceramic pressure plate extractors, were conducted to compile the SWR databank. 15 SWR models were selected and fitted to the SWR data points. Soil texture, bulk density, and organic matter were used to determine their effect on the performance of the SWR models. The results indicate that the Tani and Russo models exhibit the lowest levels of accuracy and performance among the selected models. Based on the Akaike and Bayesian information criteria analysis, the van Genuchten model exhibits the lowest values among the selected models, with poor prediction capabilities in estimating the SWR curve. The significance test at the 0.05 level (95% confidence interval) shows that according to the calculated p-values for the Pearson correlation coefficient between RMSE and texture, the Brooks-Corey and van Genuchten models are poorly influenced by soil properties. The performance of the models is not significantly affected by the soil organic matter. Similarly, bulk density does not significantly affect model performance except for the Brooks–Corey, van Genuchten, Tani, and Russo models. Among the SWR models considered, the double exponential, Groenevelt and Grant, and Khlosi et al. models demonstrate superior accuracy and performance in predicting the SWR curve. This is supported by lower values for RMSE, Akaike, and Bayesian information criteria.
Is Syntactic Priming from Multiple Speakers Stronger?
Authors: Eski Kerime Eylul , Onnis Luca
Published: April 2024

Syntactic priming in dialogue occurs when exposure to a particular syntactic structure implicitly induces a speaker’s subsequent preference for the same syntactic structures in their own speech. Here, we asked whether this priming effect is boosted when individuals are primed by several different speakers as opposed to one. In an initial baseline session involving a picture description task, we assessed adult participants’ production of double object/DO (vs. prepositional/PO) dative and passive (vs. active) transitive structures. Subsequently, participants played a picture description and verification game, in turns, with six other players (confederates). During verification turns, confederates primed participants by using DO and passive utterances. Crucially, participants were primed either by a single confederate (single-speaker priming condition, SSP) or by five confederates (multi-speaker priming condition, MSP). Across conditions, the same priming stimuli were presented in the same order, leaving speaker source/variation as the only different feature. The degree to which participants were primed for the target structures compared to baseline was measured. Results indicated a robust priming effect in both conditions. Nevertheless, the increase in the target structures’ use did not differ significantly between the SSP and MSP conditions, suggesting that speaker variation did not promote stronger priming.
Endometriosis in Menopausal Women—A New Age Is Coming? Literature Review
Authors: Dinu Mihai-Daniel , Haj Hamoud Bashar , Amza Mihaela , Gorecki Gabriel-Petre , Sima Romina-Marina , Gică Nicolae , Pleș Liana
Published: April 2024

Endometriosis is a chronic inflammatory disease, characterized by the presence of ectopic endometrial tissue, that leads to dysmenorrhea, painful intercourse and infertility. The shift in paradigm from the previous belief that endometriosis exclusively impacts women of reproductive age has brought attention to the condition in both premenarchal and postmenopausal women. Currently, 2–4% of postmenopausal women have endometriosis. Many women experience menopausal symptoms during the peri- and postmenopausal periods and require extensive investigations and monitoring in order to avoid the recurrence of endometriosis symptoms or the risk of malignant transformation when treatment with menopausal hormones is elected. Our goal was to compile and present a clear and concise overview of the existing literature on postmenopausal endometriosis, offering an up-to-date and precise summary of the available information.
Goethite Enhances Cr(VI) Reduction by S. oneidensis MR-1 under Different Conditions: Mechanistic Insights
Authors: Hou Yu , Li Yanhong , Wang Yaru , Zhu Zongqiang , Tang Shen , Zhang Jie , Pan Qiaodong , Hu Ting
Published: April 2024

Chromium (Cr) contamination, widely present in the environment, poses a significant threat to both ecology and human health. Microbial remediation technology has become a hot topic in the field of heavy metal remediation due to its advantages, such as environmental protection, low cost, and high efficiency. This paper focused on using various characterization and analysis methods to investigate the bioreduction effect and mechanism of microorganisms on Cr(VI) under various influencing factors. The main contents and conclusions were as follows: Shewanella oneidensis MR-1 was selected as the target strain for studying its reduction of Cr(VI) at different inoculation amounts, temperatures, pH values, time intervals, etc. The results indicated that S. oneidensis MR-1 exhibited an optimal reduction effect on Cr(VI) at pH 7 and a temperature of 35 °C. Additionally, electron shuttles (ESs), including humic acid (HA) and 9,10-antraquinone-2,6-disulfonate (AQDS), were introduced into the degradation system to improve the reduction efficiency of S. oneidensis MR-1. Upon adding goethite further, S. oneidensis MR-1 significantly enhanced its reducing ability by converting Fe(III) minerals to Fe(II) and reducing Cr(VI) to Cr(III) during electron transfer.
Understanding Acanthamoeba Keratitis: An In-Depth Review of a Sight-Threatening Eye Infection
Authors: Petrillo Francesco , Tortori Antonia , Vallino Veronica , Galdiero Marilena , Fea Antonio M. , De Sanctis Ugo , Reibaldi Michele
Published: April 2024

Acanthamoeba keratitis (AK) is a rare but potentially sight-threatening corneal infection caused by the Acanthamoeba parasite. This microorganism is found ubiquitously in the environment, often in freshwater, soil, and other sources of moisture. Despite its low incidence, AK presents significant challenges due to delayed diagnosis and the complex nature of therapeutic management. Early recognition is crucial to prevent severe ocular complications, including corneal ulceration and vision loss. Diagnostic modalities and treatment strategies may vary greatly depending on the clinical manifestation and the available tools. With the growing reported cases of Acanthamoeba keratitis, it is essential for the ophthalmic community to thoroughly understand this condition for its effective management and improved outcomes. This review provides a comprehensive overview of AK, encompassing its epidemiology, risk factors, pathophysiology, clinical manifestations, diagnosis, and treatment.
Short-Term Microplastics Exposure to the Common Mysid Shrimp, Americamysis bahia: Effects on Mortality and DNA Methylation
Authors: Prior Jack H. , Whitaker Justine M. , Janosik Alexis M.
Published: April 2024

Primary consumers of microplastics are often zooplankton species such as the mysid shrimp, Americamysis bahia. Ingesting and interacting with these plastics can cause stress and lead to death. In the presence of some environmental stressors, gene expression may be altered without changing DNA sequences via the epigenetic methylation of the DNA. Mysid shrimp were exposed to 5-micrometer fluorescent polystyrene microbeads at different concentrations and different lengths of time. No significant effects were observed on mortality within 72 h, but mortality increased significantly thereafter. Microplastics were consumed by mysids and adhered to the mysid carapace and appendages. An ELISA-like (Enzyme-Linked Imuunosorbent Assay) colorimetric assay was employed to assess mysid DNA for differences in global percent methylation. No significant difference in the average percent methylated DNA nor difference in the number of methylation detections between treatments was found. This is one of few studies that has investigated DNA methylation effects due to microplastics-induced stress and the first study to detect DNA methylation in any member of the order Mysida.
Empirical Correlation between Electrical Conductivity and Nitrogen Content in Biochar as Influenced by Pyrolysis Temperature
Authors: Morais Everton Geraldo de , Silva Carlos Alberto , Gao Suduan , Melo Leônidas Carrijo Azevedo , Lago Bruno Cocco , Teodoro Jéssica Cristina , Guilherme Luiz Roberto Guimarães
Published: April 2024

Much progress has been made in understanding the conditions of biochar production related to biochar properties and carbon (C). Still, very little knowledge has been gained regarding the effects on nitrogen (N), one of the most critical nutrients affected by pyrolysis temperature (PT). Analysis of N in biochar is costly, and alternative methods should be developed to estimate the N content in biochar quickly under different pyrolysis conditions. We hypothesized that there was a correlation between biochar N content and its electrical conductivity (EC). We aimed to evaluate total N and the effect of PT through the correlation with EC, a parameter that can be easily measured. Biochar products derived from coffee husk (CH) and chicken manure (CM) produced at increasing PT (300 to 750 °C) were used for the study and measured for total N and EC. The increase in PT caused significant N loss, consequently reducing total N content in biochars, with the highest loss (82%) and lowest total N content (1.2 g kg−1) found in CM biochar pyrolyzed at 750 °C. The lowest N loss (21% for CH biochar and 36% for CM biochar) was observed at a PT of 300 °C. A negative correlation between EC and total N and a positive correlation with N loss were found in both biochar products across the wide range of PT investigated. To preserve the N content in biochars, the PT should not exceed 400 °C. Our results indicate that EC is a fast and accurate biochar proxy attribute capable of predicting the N content and its loss in coffee husk and chicken manure-derived biochars as the pyrolysis temperature increased from 300 °C to 750 °C and could be used as an alternative to predict the N in biochar easily. A more extensive set of biochar samples and pyrolysis conditions should be tested to validate this approach.
Review on Minimally Extended Varying Speed of Light Model
Authors: Lee Seokcheon
Published: April 2024

It is known that dimensional constants, such as ℏ, c, G, e, and k, are merely human constructs whose values and units vary depending on the chosen system of measurement. Therefore, the time variations in dimensional constants lack operational significance due to their dependence on these dimensional constants. They are well structured and represent a valid discussion. However, this fact only becomes a meaningful debate within the context of a static or present Universe. As theoretically and observationally well established, the current Universe is undergoing accelerated expansion, wherein dimensional quantities, like the wavelength of light, also experience redshift phenomena elongating over cosmic time. In other words, in an expanding Universe, dimensional quantities of physical parameters vary with cosmic time. From this perspective, there exists the possibility that dimensional constants, such as the speed of light, could vary with the expansion of the Universe. In this review paper, we contemplate under what circumstances the speed of light may change or remain constant over cosmic time and discuss the potential for distinguishing these cases observationally.
Excited-State Dynamics of Carbazole and tert-Butyl-Carbazole in Thin Films
Authors: Knötig Konstantin Moritz , Gust Domenic , Oum Kawon , Lenzer Thomas
Published: April 2024

Thin films of carbazole (Cz) derivatives are frequently used in organic electronics, such as organic light-emitting diodes (OLEDs). Because of the proximity of the Cz units, the excited-state relaxation in such films is complicated, as intermolecular pathways, such as singlet–singlet annihilation (SSA), kinetically compete with the emission. Here, we provide an investigation of two benchmark systems employing neat carbazole and 3,6-di-tert-butylcarbazole (t-Bu-Cz) films and also their thin film blends with poly(methyl methacrylate) (PMMA). These are investigated by a combination of atomic force microscopy (AFM), femtosecond and nanosecond transient absorption spectroscopy (fs-TA and ns-TA) and time-resolved fluorescence. Excitonic J-aggregate-type features are observed in the steady-state absorption and emission spectra of the neat films. The S1 state shows a broad excited-state absorption (ESA) spanning the entire UV–Vis–NIR range. At high S1 exciton number densities of about 4 × 1018 cm−3, bimolecular diffusive S1–S1 annihilation is found to be the dominant SSA process in the neat films with a rate constant in the range of 1–2 × 10−8 cm3 s−1. SSA produces highly vibrationally excited molecules in the electronic ground state (S0*), which cool down slowly by heat transfer to the quartz substrate. The results provide relevant photophysical insight for a better microscopic understanding of carbazole relaxation in thin-film environments.
Nanosecond-Laser-Induced Breakdown of Aqueous Colloidal Solutions of Dysprosium Nanoparticles: The Influence of Nanoparticle Concentration on the Breakdown Plasma and the Intensity of Physical and Chemical Processes
Authors: Baimler Ilya V. , Baryshev Alexey S. , Dikovskaya Anastasiya O. , Chevokin Viktor K. , Uvarov Oleg V. , Astashev Maxim E. , Gudkov Sergey V. , Simakin Aleksander V.
Published: April 2024

This paper studies the dynamics of the development of laser breakdown plasma in aqueous colloids of dysprosium nanoparticles by analyzing the time patterns of plasma images obtained using a high-speed streak camera. In addition, the distribution of plasma flashes in space and their luminosity were studied, and the amplitude of acoustic signals and the rate of generation of new chemical products were studied depending on the concentration of dysprosium nanoparticles in the colloid. Laser breakdown was initiated by pulsed radiation from a nanosecond Nd:YAG laser. It is shown that the size of the plasma flash, the speed of motion of the plasma–liquid interface, and the lifetime of the plasma flash decrease with an increasing concentration of nanoparticles in the colloid. In this case, the time delay between the beginning of the laser pulse and the moment the plasma flash reaches its maximum intensity increases with increasing concentrations of nanoparticles. Varying the laser fluence in the range from 67 J/cm2 to 134 J/cm2 does not lead to noticeable changes in these parameters, due to the transition of the breakdown plasma to the critical regime. For dysprosium nanoparticles during laser breakdown of colloids, a decrease in the yield of hydrogen peroxide and an increase in the rate of formation of hydroxyl radicals per water molecule, characteristic of nanoparticles of rare earth metals, are observed, which may be due to the participation of nanoparticles and hydrogen peroxide in reactions similar to the Fenton and Haber–Weiss reactions.
Jasmonates Promote β-Amylase-Mediated Starch Degradation to Confer Cold Tolerance in Tomato Plants
Authors: Fan Xiulan , Lin Huanru , Ding Fei , Wang Meiling
Published: April 2024

Cold stress severely restricts growth and development, reduces yields, and impairs quality in tomatoes (Solanum lycopersicum). Amylase-associated starch degradation and soluble sugar accumulation have been implicated in adaptation and resistance to abiotic stress. Here, we report a β-amylase (BAM) gene, SlBAM3, which plays a central role in tomato cold tolerance. The expression of SlBAM3 was triggered by cold stress. SlBAM3 knockout using the CRISPR/Cas9 system retarded starch degradation and reduced soluble sugar accumulation in tomato plants, eventually attenuating cold tolerance. Expression analysis revealed that the SlBAM3 transcript level was boosted by MeJA. Furthermore, MYC2, an essential component of the JA signaling pathway, could bind to the SlBAM3 promoter and directly activate SlBAM3 transcription, as revealed by yeast one-hybrid and dual LUC assays. In addition, the suppression of MYC2 resulted in increased starch accumulation, decreased soluble sugar content, and reduced tolerance to cold stress in tomato plants. Taken together, these findings demonstrate that JA positively regulates β-amylase-associated starch degradation through the MYC2-SlBAM3 module in tomato during cold stress. The results of the present work expand our understanding of the mechanisms underlying BAM gene activation and starch catabolism under cold stress. The regulatory module of SlBAM3 can be further utilized to breed tomato cultivars with enhanced cold tolerance.
Characterization of Browning, Chlorogenic Acid Content, and Polyphenol Oxidase Activity in Different Varietal Types of Eggplant (Solanum melongena) for Improving Visual and Nutritional Quality
Authors: Villanueva Gloria , Vilanova Santiago , Plazas Mariola
Published: April 2024

Eggplant (Solanum melongena L.) breeding for fruit quality has mostly focused on visual traits and nutritional and bioactive compounds, including chlorogenic acid. However, higher contents of chlorogenic acid may lead to more pronounced fruit flesh browning. We examined a diverse collection of 59 eggplant accessions across five varietal types (‘black oval’, ‘striped’, ‘anthocyanin-free’, ‘purple’, and ‘black elongated’) to evaluate the degree of browning, polyphenol oxidase (PPO) activity, and chlorogenic acid (CGA) content. The results reveal moderate correlations among these traits, with no clear differences among the varietal types, suggesting that other factors, including genetic variation, might significantly influence these traits. Notably, ‘black oval’ accessions demonstrated higher browning and PPO activity, whereas ‘striped’ accessions showed low variability. The identification of genotypes with lower browning and higher CGA content highlights opportunities for targeted genotype selection to improve eggplant chlorogenic acid content while maintaining low or moderate browning, pointing towards the importance of genetic considerations in breeding strategies to reduce browning and enhance nutritional value.
Arsenic Contamination Needs Serious Attention: An Opinion and Global Scenario
Authors: Bhat Abhijnan , Ravi Kamna , Tian Furong , Singh Baljit
Published: April 2024

Arsenic (As) contamination is a serious global concern, polluting our natural resources, including water and soil, and posing a danger to the environment and public health. Arsenic is present in the groundwater of several countries and this contaminated water is used for irrigation, drinking, and food preparation, which poses the greatest threat to public health. Nearly 106 countries are affected by groundwater arsenic contamination and an estimated 230 million individuals worldwide are exposed to its adverse health effects, including increased cancer risks, associated cardiovascular disease and diabetes, skin lesions, neurological effects, kidney damage, and foetal or cognitive-development-related complications. Arsenic is highly toxic and ranked first in the priority list of ATSDR (Agency for Toxic Substances and Disease Registry, 2022) and among the 10 chemicals of major public health concern on the World Health Organization (WHO) list. The maximum permissible level of arsenic in drinking water has been established at 10 µg/L by WHO, as well as by the Environmental Protection Agency (EPA) and European Union (EU). These regulatory standards underscore the gravity of the problem, and actions to prioritise the development of effective detection, mitigation strategies, and collaborative initiatives are necessary. This opinion article covers (i) arsenic footprints—global scenario and impact, (ii) awareness and education and (iii) mitigation approaches (detection and removal strategies) and future perspectives, which collectively will help in controlling and preventing As contamination of our global water resources. Regulatory and legislative bodies and development agencies are crucial for raising awareness and countering this alarming concern by implementing collaborative actions to protect our environment and public health and to provide safe drinking water for all.
The Effect of Supplementation with Organic Acid and Oregano Oils in Drinking Water on Pekin Duck Growth and Welfare
Authors: Rocha Jessica J. , Archer Gregory S.
Published: April 2024

This study evaluated duck growth, health, and welfare in response to water supplementation with organic acid (OA) and oregano oils (OOs) in Pekin duck. The treatments used in this study included a control (CON) treatment with no water additives given, an OA treatment (ProPhorce Exclusive NC®), and an OO treatment (Nubiotic 4X Concentrate®). The OA and OO improved the feed conversion ratio (FCR) and body weight (BW) (p < 0.01) compared to the control (CON). Both OA and OO showed differences (p < 0.05) in villus height and crypt depth compared to the CON. But only OA showed an increase (p < 0.01) in villus height and villus height/crypt depth ratio. On D 35, the total plasma corticosterone levels, heterophil-to-lymphocyte ratios, and asymmetry scores for OA and OO were decreased (p < 0.05) compared to CON, indicating lower stress susceptibility. The pH levels of OA ceca and jejunum were lower (p < 0.05) compared to CON. Tibia breaking strength was increased (p = 0.02) for OA compared to CON, while no differences were found with OO (p > 0.05). In conclusion, these experiments indicate that OA and OO can be used to improve duck growth, feed efficiency, stress susceptibility, and bird welfare.
Experimental and Numerical Simulation Study on the Mechanism of Fracture-Increasing and Permeability-Increasing in Granite Pore Walls by the Air DTH Hammer Percussion Drilling
Authors: Tian Longjun , Yang Xinxiang , Zhang Renjie , Zheng Kai , Jiang Ou , Zheng Xiuhua
Published: April 2024

Air DTH (Down-The-Hole) hammer percussion drilling (vibration percussion drilling) has proven to be a highly efficient geothermal drilling technique, and percussion fractures near the wellbore benefit geothermal energy development in many ways (such as hydraulic fracturing, perforation, etc.). However, no research has been done on the mechanism of fracture-increasing and permeation-increasing in granite pore walls by air DTH hammer percussion drilling. This article: (1) using an air drilling test device, an air DTH hammer whole bit impact rock fragmentation test was conducted on granite in an atmospheric environment; (2) dyeing experiments, CT scanning, and 3D reconstruction modeling were used to characterize and identify wellbore cracks; (3) research the strength, porosity, and permeability changes of granite wellbore through mechanical and permeability testing experiments; and (4) numerical simulation of impact stress waves using particle flow code (PFC) 6.0 software to demonstrate the rationality of impact experimental results. The results show that the air DTH hammer impact can induce micro-cracks in the wellbore, and the distribution of cracks is regionalized, mainly due to the attenuation of the impact stress wave. The numerical results are consistent with the experimental results. The average strength of granite decreased by 16.5%, the average porosity increased by 9.5%, the average permeability increased by 63.3%, the porosity increased from 0.0025% to 0.03%, and the porosity increased by about 12 times under the air DTH Hammer percussion drilling. The above results provide the theoretical basis and experimental proof for the ability of air DTH hammer drilling to produce wellbore cracks and improve wellbore permeability. The presented experimental results can be a useful reference for building numerical models.
Fabrication and Characterisation of Sustainable 3D-Printed Parts Using Post-Consumer PLA Plastic and Virgin PLA Blends
Authors: Hasan Mohammad Raquibul , Davies Ian J. , Paramanik Alokesh , John Michele , Biswas Wahidul K.
Published: April 2024

Sustainable manufacturing practices are becoming increasingly necessary due to the growing concerns regarding climate change and resource scarcity. Consequently, material recycling technologies have gradually become preferred over conventional processes. This study aimed to recycle waste polylactic acid (PLA) from household-disposed cups and lids to create 3D-printed parts and promote sustainable manufacturing practices. To achieve this, the current study utilised virgin and post-consumer PLA (PC-PLA) (sourced from household waste) blends. The PC-PLA wastes were shredded and sorted by size with the aid of a washing step, resulting in a filament with a 1.70 ± 0.5 mm diameter without fragmentation or dissolution. A 50:50 wt.% blend of virgin PLA (vPLA) and PC-PLA was selected as the standard recycling percentage based on previous research and resource conservation goals. The study investigated the impact of three 3D printing parameters (layer height (LH), infill density (I), and nozzle temperature (NT)) on the quality of 3D-printed parts using a three-level L9 Taguchi orthogonal array. The findings revealed that blending PC-PLA with vPLA led to significant improvements in tensile, flexural, and impact strengths by 18.40%, 8%, and 9.15%, respectively, compared to those of recycled PLA (rPLA). This conclusion was supported by the investigation of the fracture surface area, which revealed fractographic features associated with printing parameters, such as plastic deformation and interfilament debonding. An ANOVA analysis revealed a positive influence of a greater layer height and high nozzle temperature on mechanical properties. Subsequently, the optimal printing parameters (LH: 0.3 mm, I: 100%, and NT: 215 °C) were determined using the S/N ratio, and a confirmation test using the optimum printing parameters exhibited a strong correlation with the statistically predicted outcomes. Finally, the study used optimum printing parameters to fabricate 100% PC-PLA 3D-printed parts, demonstrating their potential for low-strength applications. The findings suggest that employing vPLA and PC-PLA blended filaments for fabricating 3D-printed components presents an effective means of promoting plastic recycling within a closed-loop recycling system and achieving a circular economy.
Relationship between Occupational Pension, Corporate Social Responsibility (CSR), and Organizational Resilience: A Study on Listed Chinese Companies
Authors: Wang Hao , Zhang Tao , Wang Xi , Zheng Jiansong
Published: April 2024

Numerous researchers acknowledge that the occupational pension protects employees. However, in China, the total cost of occupational pensions is shared between employees and employers, representing a significant financial commitment. This study aimed to explore the effect of the occupational pension on corporate social responsibility (CSR) and organizational resilience. Drawing on insights from cost-stickiness and resource-based theories, we developed a model that elucidated the influence of occupational pensions on firms’ approaches to CSR within the context of COVID-19 and how this, in turn, impacted organizational resilience. This study categorized CSR into strategic and responsive activities, employing the concept of cost stickiness as a framework. We analyzed a sample of 34,145 observations from Chinese A-share listed companies spanning the period 2010–2023 to examine the influence of occupational pension adjustments on CSR strategies. The findings of this study revealed that the cost pressure associated with contributions to occupational pensions prompted firms to decrease their engagement in responsive CSR activities while enhancing their strategic CSR initiatives. Furthermore, it was observed that strategic CSR contributed to improved organizational resilience, whereas responsive CSR did not exhibit the same effect. The relationship between occupational pension contributions and CSR was found to be significantly and negatively moderated by factors such as the minimum wage and population aging. Conversely, the relationship between CSR and organizational resilience was significantly and positively moderated by digital transformation and marketing capabilities.