bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimal Load Shedding for Maximizing Satisfaction in an Islanded Microgrid
Authors: Choi Yeongho , Lim Yujin , Kim Hak-Man
Published: January 2017

A microgrid (MG) is a discrete energy system that can operate either in parallel with or independently from a main power grid. It is designed to enhance reliability, carbon emission reduction, diversification of energy sources, and cost reduction. When a power fault occurs in a grid, an MG operates in an islanded manner from the grid and protects its power generations and loads from disturbance by means of intelligent load shedding. A load shedding is a control procedure that results in autonomous decrease of the power demands of loads in an MG. In this study, we propose a load shedding algorithm for the optimization problem to maximize the satisfaction of system components. The proposed algorithm preferentially assigns the power to the subdemand with a high preference to maximize the satisfaction of power consumers. In addition, the algorithm assigns the power to maximize the power sale and minimize the power surplus for satisfaction of power suppliers. To verify the performance of our algorithm, we implement a multi-agent system (MAS) on top of a conventional development framework and assess the algorithm’s adaptability, satisfaction metric, and running time.
Conjugate Image Theory Applied on Capacitive Wireless Power Transfer
Authors: Minnaert Ben , Stevens Nobby
Published: January 2017

Wireless power transfer using a magnetic field through inductive coupling is steadily entering the market in a broad range of applications. However, for certain applications, capacitive wireless power transfer using electric coupling might be preferable. In order to obtain a maximum power transfer efficiency, an optimal compensation network must be designed at the input and output ports of the capacitive wireless link. In this work, the conjugate image theory is applied to determine this optimal network as a function of the characteristics of the capacitive wireless link, as well for the series as for the parallel topology. The results are compared with the inductive power transfer system. Introduction of a new concept, the coupling function, enables the description of the compensation network of both an inductive and a capacitive system in two elegant equations, valid for the series and the parallel topology. This approach allows better understanding of the fundamentals of the wireless power transfer link, necessary for the design of an efficient system.
A Fiber Optic Fabry–Perot Cavity Sensor for the Probing of Oily Samples
Authors: Melissinaki Vasileia , Farsari Maria , Pissadakis Stavros
Published: January 2017

A micro-optical Fabry–Perot cavity fabricated by non-linear laser lithography on the endface of a standard telecom fiber is tested here as a microsensor for identifying oily liquids. The device operates within the 1550 nm spectral region, while the spectra recorded in reflection mode correlate to the refractive index of the oily liquids used, as well as, to the diffusion dynamics in the time domain of the oily samples inside the porous photo-polymerized sensing head. The operation of the microresonator sensing probe is explained by using a three-layer Fabry–Perot model and basic diffusion physics to estimate diffusivities for three series of refractive index matching oils with different chemical compositions that had been used in those experiments. The distinct spectro-temporal response of this sensing probe to the different oil samples is demonstrated and discussed.
Cognitive Hierarchy Theory and Two-Person Games
Authors: Gracia-Lázaro Carlos , Floría Luis , Moreno Yamir
Published: January 2017

The outcome of many social and economic interactions, such as stock-market transactions, is strongly determined by the predictions that agents make about the behavior of other individuals. Cognitive hierarchy theory provides a framework to model the consequences of forecasting accuracy that has proven to fit data from certain types of game theory experiments, such as Keynesian beauty contests and entry games. Here, we focus on symmetric two-player-two-action games and establish an algorithm to find the players’ strategies according to the cognitive hierarchy approach. We show that the snowdrift game exhibits a pattern of behavior whose complexity grows as the cognitive levels of players increases. In addition to finding the solutions up to the third cognitive level, we demonstrate, in this theoretical frame, two new properties of snowdrift games: (i) any snowdrift game can be characterized by only a parameter, its class; (ii) they are anti-symmetric with respect to the diagonal of the pay-off’s space. Finally, we propose a model based on an evolutionary dynamics that captures the main features of the cognitive hierarchy theory.
Strategy Constrained by Cognitive Limits, and the Rationality of Belief-Revision Policies
Authors: Sperry-Taylor Ashton
Published: January 2017

Strategy is formally defined as a complete plan of action for every contingency in a game. Ideal agents can evaluate every contingency. But real people cannot do so, and require a belief-revision policy to guide their choices in unforeseen contingencies. The objects of belief-revision policies are beliefs, not strategies and acts. Thus, the rationality of belief-revision policies is subject to Bayesian epistemology. The components of any belief-revision policy are credences constrained by the probability axioms, by conditionalization, and by the principles of indifference and of regularity. The principle of indifference states that an agent updates his credences proportionally to the evidence, and no more. The principle of regularity states that an agent assigns contingent propositions a positive (but uncertain) credence. The result is rational constraints on real people’s credences that account for their uncertainty. Nonetheless, there is the open problem of non-evidential components that affect people’s credence distributions, despite the rational constraint on those credences. One non-evidential component is people’s temperaments, which affect people’s evaluation of evidence. The result is there might not be a proper recommendation of a strategy profile for a game (in terms of a solution concept), despite agents’ beliefs and corresponding acts being rational.
Which Food Security Determinants Predict Adequate Vegetable Consumption among Rural Western Australian Children?
Authors: Godrich Stephanie , Lo Johnny , Davies Christina , Darby Jill , Devine Amanda
Published: January 2017

Improving the suboptimal vegetable consumption among the majority of Australian children is imperative in reducing chronic disease risk. The objective of this research was to determine whether there was a relationship between food security determinants (FSD) (i.e., food availability, access, and utilisation dimensions) and adequate vegetable consumption among children living in regional and remote Western Australia (WA). Caregiver-child dyads (n = 256) living in non-metropolitan/rural WA completed cross-sectional surveys that included questions on FSD, demographics and usual vegetable intake. A total of 187 dyads were included in analyses, which included descriptive and logistic regression analyses via IBM SPSS (version 23). A total of 13.4% of children in this sample had adequate vegetable intake. FSD that met inclusion criteria (p ≤ 0.20) for multivariable regression analyses included price; promotion; quality; location of food outlets; variety of vegetable types; financial resources; and transport to outlets. After adjustment for potential demographic confounders, the FSD that predicted adequate vegetable consumption were, variety of vegetable types consumed (p = 0.007), promotion (p = 0.017), location of food outlets (p = 0.027), and price (p = 0.043). Food retail outlets should ensure that adequate varieties of vegetable types (i.e., fresh, frozen, tinned) are available, vegetable messages should be promoted through food retail outlets and in community settings, towns should include a range of vegetable purchasing options, increase their reliance on a local food supply and increase transport options to enable affordable vegetable purchasing.
A Comprehensive Proteomic Survey of ABA-Induced Protein Phosphorylation in Rice (Oryza sativa L.)
Authors: Qiu Jiehua , Hou Yuxuan , Wang Yifeng , Li Zhiyong , Zhao Juan , Tong Xiaohong , Lin Haiyan , Wei Xiangjin , Ao Hejun , Zhang Jian
Published: January 2017

abscisic acid (ABA) is a key phytohormone regulating plant development and stress response. The signal transduction of ABA largely relies on protein phosphorylation. However; little is known about the phosphorylation events occurring during ABA signaling in rice thus far. By employing a label-free; MS (Mass Spectrometry)-based phosphoproteomic approach; we identified 2271 phosphosites of young rice seedlings and their intensity dynamics in response to ABA; during which 1060 proteins were found to be differentially phosphorylated. Western-blot analysis verified the differential phosphorylation pattern of D1, SMG1 and SAPK9 as indicated by the MS result; suggesting the high reliability of our phosphoproteomic data. The DP (differentially phosphorylated) proteins are extensively involved in ABA as well as other hormone signaling pathways. It is suggested that ABA antagonistically regulates brassinosteroid (BR) signaling via inhibiting BR receptor activity. The result of this study not only expanded our knowledge of rice phosphoproteome, but also shed more light on the pattern of protein phosphorylation in ABA signaling.
Using Vital Dyes to Trace Uptake of dsRNA by Green Peach Aphid Allows Effective Assessment of Target Gene Knockdown
Authors: Bilgi Vineeta , Fosu-Nyarko John , Jones Michael
Published: January 2017

RNA interference (RNAi) is an effective tool to study gene function. For in vitro studies of RNAi in insects, microinjection of double-stranded (ds)RNA may cause stress. Non-persuasive oral delivery of dsRNA to trigger RNAi is a better mode of delivery for delicate insects such as aphids because it mimics natural feeding. However, when insects feed ad libitum, some individuals may not feed. For accurate measurement of gene knockdown, analysis should only include insects that have ingested dsRNA. The suitability of eleven dyes was assessed to trace ingestion of dsRNA in an artificial feeding system for green peach aphids (GPA, Myzus persicae). Non-toxic levels of neutral red and acridine orange were suitable tracers: they were visible in the stylet and gut after feeding for 24 h, and may also attract aphids to feed. Nymphs stained with neutral red (0.02%) were analysed for target gene expression after feeding on sucrose with dsRNA (V-ATPase, vha-8). There was a greater reduction in vha-8 expression and reproduction compared to nymphs fed the diet without dye. The results confirm the importance of identifying aphids that have ingested dsRNA, and also provide evidence that the vha-8 gene is a potential target for control of GPAs.
Somatic Genetic Variation in Solid Pseudopapillary Tumor of the Pancreas by Whole Exome Sequencing
Authors: Guo Meng , Luo Guopei , Jin Kaizhou , Long Jiang , Cheng He , Lu Yu , Wang Zhengshi , Yang Chao , Xu Jin , Ni Quanxing , Yu Xianjun , Liu Chen
Published: January 2017

Solid pseudopapillary tumor of the pancreas (SPT) is a rare pancreatic disease with a unique clinical manifestation. Although CTNNB1 gene mutations had been universally reported, genetic variation profiles of SPT are largely unidentified. We conducted whole exome sequencing in nine SPT patients to probe the SPT-specific insertions and deletions (indels) and single nucleotide polymorphisms (SNPs). In total, 54 SNPs and 41 indels of prominent variations were demonstrated through parallel exome sequencing. We detected that CTNNB1 mutations presented throughout all patients studied (100%), and a higher count of SNPs was particularly detected in patients with older age, larger tumor, and metastatic disease. By aggregating 95 detected variation events and viewing the interconnections among each of the genes with variations, CTNNB1 was identified as the core portion in the network, which might collaborate with other events such as variations of USP9X, EP400, HTT, MED12, and PKD1 to regulate tumorigenesis. Pathway analysis showed that the events involved in other cancers had the potential to influence the progression of the SNPs count. Our study revealed an insight into the variation of the gene encoding region underlying solid-pseudopapillary neoplasm tumorigenesis. The detection of these variations might partly reflect the potential molecular mechanism.
Muscle Carnitine Palmitoyltransferase II Deficiency: A Review of Enzymatic Controversy and Clinical Features
Authors: Lehmann Diana , Motlagh Leila , Robaa Dina , Zierz Stephan
Published: January 2017

CPT (carnitine palmitoyltransferase) II muscle deficiency is the most common form of muscle fatty acid metabolism disorders. In contrast to carnitine deficiency, it is clinically characterized by attacks of myalgia and rhabdomyolysis without persistent muscle weakness and lipid accumulation in muscle fibers. The biochemical consequences of the disease-causing mutations are still discussed controversially. CPT activity in muscles of patients with CPT II deficiency ranged from not detectable to reduced to normal. Based on the observation that in patients, total CPT is completely inhibited by malony-CoA, a deficiency of malonyl-CoA-insensitive CPT II has been suggested. In contrast, it has also been shown that in muscle CPT II deficiency, CPT II protein is present in normal concentrations with normal enzymatic activity. However, CPT II in patients is abnormally sensitive to inhibition by malonyl-CoA, Triton X-100 and fatty acid metabolites. A recent study on human recombinant CPT II enzymes (His6-N-hCPT2 and His6-N-hCPT2/S113L) revealed that the wild-type and the S113L variants showed the same enzymatic activity. However, the mutated enzyme showed an abnormal thermal destabilization at 40 and 45 °C and an abnormal sensitivity to inhibition by malony-CoA. The thermolability of the mutant enzyme might explain why symptoms in muscle CPT II deficiency mainly occur during prolonged exercise, infections and exposure to cold. In addition, the abnormally regulated enzyme might be mostly inhibited when the fatty acid metabolism is stressed.
rs657075 (CSF2) Is Associated with the Disease Phenotype (BAS-G) of Ankylosing Spondylitis
Authors: Chen Wei-Chiao , Wei James , Lu Hsing-Fang , Wong Henry , Woon Peng , Hsu Yu-Wen , Huang Jin-Ding , Chang Wei-Chiao
Published: January 2017

Ankylosing spondylitis (AS) is a systemic autoimmune disease mainly affecting the lumbar spine and sacroiliac joints, and exhibits peripheral inflammatory arthropathy. More than 25 loci have been identified as associated with AS. Because both AS and rheumatoid arthritis (RA) are autoimmune diseases that may share some common genetic factors, we therefore examined if the newly identified RA genetic polymorphisms were associated with AS in a Taiwanese population. In this study, we enrolled 475 AS patients and 11,301 healthy subjects from a Taiwanese biobank as controls. Although none of single-nucleotide polymorphisms (SNPs) were associated with the susceptibility to AS, the AS disease index Bath AS Global (BAS-G) clinical phenotype was observed as significantly correlated to the AA genotype of rs657075 (CSF2). The significance remains after gender/age/disease duration adjustment and after group categorization by human leukocyte antigen-B 27 (HLA-B27) genotype. We further investigated the possible functions of rs657075 through bioinformatics approaches. Results revealed that polymorphism of rs657075 is able to influence the expression of acyl-CoA synthetase long-chain family member 6 (ACSL6). In conclusion, our study indicated that rs657075 (CSF2) is strongly associated with the AS disease index Bath AS Global (BAS-G) clinical phenotype.
Model Based Safety Analysis with smartIflow
Authors: Hönig Philipp , Lunde Rüdiger , Holzapfel Florian
Published: January 2017

Verification of safety requirements is one important task during the development of safety critical systems. The increasing complexity of systems makes manual analysis almost impossible. This paper introduces a new methodology for formal verification of technical systems with smartIflow (State Machines for Automation of Reliability-related Tasks using Information FLOWs). smartIflow is a new modeling language that has been especially designed for the purpose of automating the safety analysis process in early product life cycle stages. It builds up on experience with existing approaches. As is common practice in current approaches, components are modeled as finite state machines. However, new concepts are introduced to describe component interactions. Events play a major role for internal interactions between components as well as for external (user) interactions. Our approach to the verification of formally specified safety requirements is a two-step method. First, an exhaustive simulation creates knowledge about a great variety of possible behaviors of the system, especially including reactions on suddenly occurring (possibly intermittent) faults. In the second step, safety requirements specified in CTL (Computation Tree Logic) are verified using model checking techniques, and counterexamples are generated if these are not satisfied. The practical applicability of this approach is demonstrated based on a Java implementation using a simple Two-Tank-Pump-Consumer system.
Comparative Analysis of Triangulation Libraries for Modeling Large Point Clouds from Land and Their Infrastructures
Authors: Lopez-Fernandez Luis , Rodriguez-Gonzalvez Pablo , Hernandez-Lopez David , Ortega-Terol Damian , Gonzalez-Aguilera Diego
Published: January 2017

Although the generation of large points clouds from geomatic techniques allows us to realize the topography and appearance of the terrain and its infrastructures (e.g., roads, bridges, buildings, etc.), all these 3D point clouds require an unavoidable step to be conveniently treated: the definition of the surface that connects these points in space through digital surface models (DSM). In addition, these point clouds sometimes have associated attributes and geometric constraints such as breaklines and/or exclusion areas, which require the implementation of efficient triangulation techniques that can cope with a high volume of information. This article aims to make a comparative analysis of different Delaunay triangulation libraries, open or with academic versions available for the scientific community, so that we can assess their suitability for the modeling of the territory and its infrastructures. The comparison was carried out from a two-fold perspective: (i) to analyze and compare the computational cost of the triangulation; (ii) to assess the geometric quality of the resulting meshes. The different techniques and libraries have been tested based on three different study cases and the corresponding large points clouds generated. The study has been useful to identify the limitations of the existing large point clouds triangulation libraries and to propose statistical variables that assess the geometric quality of the resulting DSM.
A Nutritional Profile of the Trap-Nesting Wasp Trypoxylon lactitarse (Hymenoptera: Crabronidae): Comparison of Sexes and Overwintering and Non-Overwintering Generations
Authors: Judd Timothy , Fasnacht Matthew
Published: January 2017

The wasp Trypoxylon lactitarse Saussure is a bivoltine trap-nesting species that possesses a non-overwintering generation (G1) and a generation that overwinters as a prepupa (G2). Thus, the nutritional needs of the G1 individuals were predicted to be different than the G2 because the latter generation needs to store energy prior to diapause. Trap-nesting Trypoxylon are also of interest because, unlike most Hymenoptera, the males guard the nest while females forage. Thus, males may lose nutrients as they stay and guard the nest. In this study, a nutritional profile was created for T. lactitarse to compare the macronutrient (protein, carbohydrates, and lipids) and micronutrient (Ca, Cu, Fe, K, Mg, Mn, Na, and Zn) levels of the different life stages of the wasp and compare individuals of the G1 and G2 generations. There were distinct changes in the nutrient levels relative to the original food source as individuals metamorphosed into larvae, pupae, and adults. G1 larvae had higher levels of carbohydrates than G2 larvae. G2 larvae had higher levels of lipids and K than G1 larvae, indicating possible differences in energy storage. In adults, there was an increase in levels of carbohydrates and Mn. Parental males, which stay and guard the nest, were found to have higher levels of carbohydrates at the end of the nesting period than females and emerging adults. One possible implication is that females may feed males during the nesting period, as the females are the only individuals to forage.
Portfolio Optimization and Mortgage Choice
Authors: Nordfang Maj-Britt , Steffensen Mogens
Published: January 2017

This paper studies the optimal mortgage choice of an investor in a simple bond market with a stochastic interest rate and access to term life insurance. The study is based on advances in stochastic control theory, which provides analytical solutions to portfolio problems with a stochastic interest rate. We derive the optimal portfolio of a mortgagor in a simple framework and formulate stylized versions of mortgage products offered in the market today. This allows us to analyze the optimal investment strategy in terms of optimal mortgage choice. We conclude that certain extreme investors optimally choose either a traditional fixed rate mortgage or an adjustable rate mortgage, while investors with moderate risk aversion and income prefer a mix of the two. By matching specific investor characteristics to existing mortgage products, our study provides a better understanding of the complex and yet restricted mortgage choice faced by many household investors. In addition, the simple analytical framework enables a detailed analysis of how changes to market, income and preference parameters affect the optimal mortgage choice.
Hydrological Response to ~30 years of Agricultural Surface Water Management
Authors: Sofia Giulia , Tarolli Paolo
Published: January 2017

Amongst human practices, agricultural surface-water management systems represent some of the largest integrated engineering works that shaped floodplains during history, directly or indirectly affecting the landscape. As a result of changes in agricultural practices and land use, many drainage networks have changed producing a greater exposure to flooding with a broad range of impacts on society, also because of climate inputs coupling with the human drivers. This research focuses on three main questions: which kind of land use changes related to the agricultural practices have been observed in the most recent years (~30 years)? How does the influence on the watershed response to land use and land cover changes depend on the rainfall event characteristics and soil conditions, and what is their related significance? The investigation presented in this work includes modelling the water infiltration due to the soil properties and analysing the distributed water storage offered by the agricultural drainage system in a study area in Veneto (north-eastern Italy). The results show that economic changes control the development of agro-industrial landscapes, with effects on the hydrological response. Key elements that can enhance or reduce differences are the antecedent soil conditions and the climate characteristics. Criticalities should be expected for intense and irregular rainfall events, and for events that recurrently happen. Agricultural areas might be perceived to be of low priority when it comes to public funding of flood protection, compared to the priority given to urban ones. These outcomes highlight the importance of understanding how agricultural practices can be the driver of or can be used to avoid, or at least mitigate, flooding. The proposed methods can be valuable tools in evaluating the costs and benefits of the management of water in agriculture to inform better policy decision-making.
Influence of Porous Spherical-Shaped Hydroxyapatite on Mechanical Strength and Bioactive Function of Conventional Glass Ionomer Cement
Authors: Chiu Szu-Yu , Shinonaga Yukari , Abe Yoko , Harada Kyoko , Arita Kenji
Published: January 2017

Glass-ionomer-cement (GIC) is helpful in Minimal Intervention Dentistry because it releases fluoride ions and is highly biocompatible. The aim of this study is to investigate the mechanisms by which hydroxyapatite (HAp) improves the mechanical strength and bioactive functioning of GIC when these materials are combined to make apatite ionomer cement (AIC). A conventional GIC powder was mixed with porous, spherical-HAp particles (HApS), crystalline HAp (HAp200) or one of two types of cellulose. The micro-compressive strengths of the additive particles were measured, and various specimens were evaluated with regard to their compressive strengths (CS), fluoride release concentrations (fluoride electrode) and multi-element release concentrations. The AIC was found to release higher concentrations of fluoride (1.2 times) and strontium ions (1.5 times) compared to the control GIC. It was detected the more release of calcium originated from HApS than HAp200 in AIC. The CS of the AIC incorporating an optimum level of HAp was also significantly higher than that of the GIC. These results suggest that adding HAp can increase the release concentration of ions required for remineralization while maintaining the CS of the GIC. This effect does not result from a physical phenomenon, but rather from chemical reactions between the HAp and polyacrylic acid of GIC.
Mechanistic Characteristics of Surface Modified Organic Semiconductor g-C3N4 Nanotubes Alloyed with Titania
Authors: Sim Lan , Tan Wei , Leong Kah , Bashir Mohammed , Saravanan Pichiah , Surib Nur
Published: January 2017

The visible-light-driven photocatalytic degradation of Bisphenol A (BPA) was investigated using the binary composite of alkaline treated g-C3N4 (HT-g-C3N4) deposited over commercial TiO2 (Evonik Degussa GmbH, Essen, Germany). The existence and contribution of both TiO2 and g-C3N4/HT-g-C3N4 in the composite was confirmed through various analytical techniques including powder X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), field emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), ultraviolet-visible diffuse reflectance spectra (UV-vis-DRS), and photoluminescence (PL) analysis. The results showed that the titania in the binary composite exhibited both pure rutile and anatase phases. The morphological analysis indicated that the spongy “morel-like” structure of g-C3N4 turned to nanotube form after alkaline hydrothermal treatment and thereby decreased the specific surface area of HT-g-C3N4. The low surface area of HT-g-C3N4 dominates its promising optical property and effective charge transfer, resulting in a deprived degradation efficiency of BPA two times lower than pure g-C3N4. The binary composite of HT-g-C3N4/TiO2 exhibited excellent degradation efficiency of BPA with 2.16 times higher than the pure HT-g-C3N4. The enhanced photocatalytic activity was mainly due to the promising optical band gap structure with heterojunction interface, favorable specific surface area, and good charge separation.
An Overview of Scaffold Design and Fabrication Technology for Engineered Knee Meniscus
Authors: Sun Jie , Vijayavenkataraman Sanjairaj , Liu Hang
Published: January 2017

Current surgical treatments for meniscal tears suffer from subsequent degeneration of knee joints, limited donor organs and inconsistent post-treatment results. Three clinical scaffolds (Menaflex CMI, Actifit® scaffold and NUsurface® Meniscus Implant) are available on the market, but additional data are needed to properly evaluate their safety and effectiveness. Thus, many scaffold-based research activities have been done to develop new materials, structures and fabrication technologies to mimic native meniscus for cell attachment and subsequent tissue development, and restore functionalities of injured meniscus for long-term effects. This study begins with a synopsis of relevant structural features of meniscus and goes on to describe the critical considerations. Promising advances made in the field of meniscal scaffolding technology, in terms of biocompatible materials, fabrication methods, structure design and their impact on mechanical and biological properties are discussed in detail. Among all the scaffolding technologies, additive manufacturing (AM) is very promising because of its ability to precisely control fiber diameter, orientation, and pore network micro-architecture to mimic the native meniscus microenvironment.
Monitoring the Damage State of Fiber Reinforced Composites Using an FBG Network for Failure Prediction
Authors: Kocaman Esat , Akay Erdem , Yilmaz Cagatay , Turkmen Halit , Misirlioglu Ibrahim , Suleman Afzal , Yildiz Mehmet
Published: January 2017

A structural health monitoring (SHM) study of biaxial glass fibre-reinforced epoxy matrix composites under a constant, high strain uniaxial fatigue loading is performed using fibre Bragg grating (FBG) optical sensors embedded in composites at various locations to monitor the evolution of local strains, thereby understanding the damage mechanisms. Concurrently, the temperature changes of the samples during the fatigue test have also been monitored at the same locations. Close to fracture, significant variations in local temperatures and strains are observed, and it is shown that the variations in temperature and strain can be used to predict imminent fracture. It is noted that the latter information cannot be obtained using external strain gages, which underlines the importance of the tracking of local strains internally.
Preparation of Protein Nanoparticles Using NTA End Functionalized Polystyrenes on the Interface of a Multi-Laminated Flow Formed in a Microchannel
Authors: Jeon Hyeong , Lee Chae , Kim Moon , Nguyen Xuan , Park Dong , Kim Hyung , Go Jeung , Paik Hyun-jong
Published: January 2017

This paper challenges the production of the protein nanoparticles using the conjugation of Ni2+ complexed nitrilotriacetic acid end-functionalized polystyrene (Ni-NTA-PS) and histidine tagged GFP (His-GFP) hybrid. The microfluidic synthesis of the protein nanoparticle with the advantages of a uniform size, a fast reaction, and a precise control of preparation conditions is examined. The self-assembly occurs on the interfacial surface of the multi-laminated laminar flow stably formed in the microchannel. The clogging of the produced protein nanoparticles on the channel surface is solved by adding a retarding inlet channel. The size and shape of the produced protein nanoparticles are measured by the analysis of transmission electron microscopy (TEM) and scanning electron microscope (SEM) images, and the attachment of the protein is visualized with a green fluorescent image. Future research includes the encapsulation of vaccines and the coating of antigens on the protein surface.
An Investigation of the Uniaxial Compressive Strength of a Cemented Hydraulic Backfill Made of Alluvial Sand
Authors: Liu Guangsheng , Li Li , Yao Mike , Landry David , Malek Farid , Yang Xiaocong , Guo Lijie
Published: January 2017

Backfill is commonly used in underground mines. The quality control of the backfill is a key step to ensure it meets the designed strength requirement. This is done through sample collection from the underground environment, followed by uniaxial compression tests to obtain the Uniaxial Compressive Strength (UCS) in the laboratory. When the cylindrical cemented backfill samples are axially loaded to failure, several failure modes can be observed and mainly classified into diagonal shear failure and axial split failure. To date, the UCS obtained by these two failure modes are considered to be the same with no distinction between them. In this paper, an analysis of the UCS results obtained on a cemented hydraulic backfill made of alluvial sand at a Canadian underground mine over the course of more than three years is presented. The results show that the UCS values obtained by diagonal shear failure are generally higher than those obtained by axial split failure for samples with the same recipe and curing time. This highlights the importance of making a distinction between the UCS values obtained by the two different modes of failure. Their difference in failure mechanism is explained. Further investigations on the sources of the data dispersion tend to indicate that the UCS obtained by laboratory tests following the current practice may not be representative of the in-situ strength distribution in the underground stopes due to segregation in cemented hydraulic backfill.
Plant Growth Biostimulants, Dietary Feed Supplements and Cosmetics Formulated with Supercritical CO2 Algal Extracts
Authors: Michalak Izabela , Chojnacka Katarzyna , Saeid Agnieszka
Published: January 2017

The review paper presents the use of algal extracts as safe and solvent-free components of plant growth biostimulants, dietary feed additives and cosmetics. Innovative technology that uses extracts obtained by supercritical CO2 extraction, as a method of isolation of biologically active compounds from algal biomass, is presented. An important part of the complete technology is the final formulation of the product. This enabled realization of the further step which was assessment of the utilitarian properties of the extract-based products. The extracts were analysed for the presence of biologically active molecules (e.g., plant hormones, polyphenols) which provide useful properties such as antioxidant, antiviral, anti-inflammatory and antibacterial. The bio-products were tested in germination tests and underwent field trials to search for plant growth biostimulatory properties. Tests on animals (laying hens experiments) were conducted to assess pro-health properties of new dietary feed supplement. Another application were cosmetic formulations (dermatological tests). The results of the application tests were very promising, however further studies are required for the registration of the products and successful implementation to the market.
Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A
Authors: Sordon Sandra , Popłoński Jarosław , Tronina Tomasz , Huszcza Ewa
Published: January 2017

Biotransformation of daidzein, genistein and biochanin A by three selected filamentous fungi was investigated. As a result of biotransformations, six glycosylation products were obtained. Fungus Beauveria bassiana converted all tested isoflavones to 4″-O-methyl-7-O-glucosyl derivatives, whereas Absidia coerulea and Absidia glauca were able to transform genistein and biochanin A to genistin and sissotrin, respectively. In the culture of Absidia coerulea, in addition to the sissotrin, the product of glucosylation at position 5 was formed. Two of the obtained compounds have not been published so far: 4″-O-methyl-7-O-glucosyl biochanin A and 5-O-glucosyl biochanin A (isosissotrin). Biotransformation products were obtained with 22%–40% isolated yield.
Impact of Probiotic Administration on Serum C-Reactive Protein Concentrations: Systematic Review and Meta-Analysis of Randomized Control Trials
Authors: Mazidi Mohsen , Rezaie Peyman , Ferns Gordon , Vatanparast Hassan
Published: January 2017

We conducted this systematic review and meta-analysis of prospective studies to determine the effect of probiotic administration on serum C-reactive protein (CRP) concentrations. We searched PubMed-Medline, Web of Science, the Cochrane, and Google Scholar databases (until May 2016) to identify prospective studies evaluating the impact of probiotic administration on CRP. We used a random effects models and generic inverse variance methods to synthesize quantitative data, followed by a leave-one-out method for sensitivity analysis. The systematic review registration number was: CRD42016039457. From a total of 425 entries identified via searches, 20 studies were included in the final analysis. The meta-analysis indicated a significant reduction in serum CRP following probiotic administration with a weighted mean difference (WMD) of −1.35 mg/L, (95% confidence interval (CI) −2.15 to −0.55, I2 65.1%). The WMDs for interleukin 10 (IL10) was −1.65 pg/dL, (95% CI −3.45 to 0.14, I2 3.1%), and −0.45 pg/mL, (95% CI −1.38 to 0.48, I2 10.2%) for tumor necrosis factor alpha (TNF-α). These findings were robust in sensitivity analyses. This meta-analysis suggests that probiotic administration may significantly reduce serum CRP while having no significant effect on serum IL10 and TNF-α.
Evolution of Gluten Content in Cereal-Based Gluten-Free Products: An Overview from 1998 to 2016
Authors: Bustamante María , Fernández-Gil María , Churruca Itziar , Miranda Jonatan , Lasa Arrate , Navarro Virginia , Simón Edurne
Published: January 2017

The treatment of Celiac disease consists in a strict lifelong gluten-free (GF) diet. As the ingestion of small amounts can have damaging complications, there has been an ongoing discussion regarding the safe threshold for dietary residual gluten. The aim was to analyze the evolution of gluten content in cereal-based GF foodstuffs (n = 3141) from 1998 to 2016 measured by the enzyme-linked immunosorbent assay (ELISA) technique. Eight categories were defined: flours, breakfast cereals/bars, bakery, pasta, breads, dough, snacks, and yeasts, and these were divided into GF labeled-foods (GF-L) or reportedly GF foodstuffs, but not certified (GF-NC). Gluten-detection was decreased over time in line with the evolving European regulations about food information and gluten content claims. This decline started sooner in GF-L products than in GF-NC. As a whole, gluten was detected in 371 samples, with breakfast cereals/bars being the most contaminated group. Snacks and yeasts changed from being high gluten-detected samples to being totally GF over the years. The downside is that, of contaminated samples, those in the low levels of gluten detection range have decreased while flour samples containing over 100 mg/kg gluten have risen in the 2013–2016 period. Obtained data confirm that GF cereal-based foods are becoming safer but gluten control must be maintained.
Effects of Resveratrol on Cognitive Performance, Mood and Cerebrovascular Function in Post-Menopausal Women; A 14-Week Randomised Placebo-Controlled Intervention Trial
Authors: Evans Hamish , Howe Peter , Wong Rachel
Published: January 2017

We tested whether chronic supplementation with resveratrol (a phytoestrogen) could improve cerebrovascular function, cognition and mood in post-menopausal women. Eighty post-menopausal women aged 45–85 years were randomised to take trans-resveratrol or placebo for 14 weeks and the effects on cognitive performance, cerebral blood flow velocity and pulsatility index (a measure of arterial stiffness) in the middle cerebral artery (using transcranial Doppler ultrasound), and cerebrovascular responsiveness (CVR) to both cognitive testing and hypercapnia were assessed. Mood questionnaires were also administered. Compared to placebo, resveratrol elicited 17% increases in CVR to both hypercapnic (p = 0.010) and cognitive stimuli (p = 0.002). Significant improvements were observed in the performance of cognitive tasks in the domain of verbal memory (p = 0.041) and in overall cognitive performance (p = 0.020), which correlated with the increase in CVR (r = 0.327; p = 0.048). Mood tended to improve in multiple measures, although not significantly. These results indicate that regular consumption of a modest dose of resveratrol can enhance both cerebrovascular function and cognition in post-menopausal women, potentially reducing their heightened risk of accelerated cognitive decline and offering a promising therapeutic treatment for menopause-related cognitive decline.
Effects of Chronic Vitamin D3 Hormone Administration on Anxiety-Like Behavior in Adult Female Rats after Long-Term Ovariectomy
Authors: Fedotova Julia , Pivina Svetlana , Sushko Anastasia
Published: January 2017

The present preclinical study was created to determine the therapeutic effects of vitamin D hormone treatment as an adjunctive therapy alone or in a combination with low dose of 17β-estradiol (17β-E2) on anxiety-like behavior in female rats with long-term absence of estrogen. Accordingly, the aim of the current study was to examine the effects of chronic cholecalciferol administration (1.0, 2.5 or 5.0 mg/kg subcutaneously, SC, once daily, for 14 days) on the anxiety-like state after long-term ovariectomy in female rats. Twelve weeks postovariectomy, cholecalciferol was administered to ovariectomized (OVX) rats and OVX rats treated with 17β-E2 (0.5 µg/rat SC, once daily, for 14 days). Anxiety-like behavior was assessed in the elevated plus maze (EPM) and the light/dark test (LDT), and locomotor and grooming activities were tested in the open field test (OFT). Cholecalciferol at two doses of 1.0 and 2.5 mg/kg alone or in combination with 17β-E2 produced anxiolytic-like effects in OVX rats as evidenced in the EPM and the LDT, as well as increased grooming activity in the OFT. Our results indicate that cholecalciferol, at two doses of 1.0 and 2.5 mg/kg, has a profound anxiolytic-like effects in the experimental rat model of long-term estrogen deficiency.
Future Scenarios for Software-Defined Metro and Access Networks and Software-Defined Photonics
Authors: Muciaccia Tommaso , Passaro Vittorio
Published: January 2017

In recent years, architectures, devices, and components in telecommunication networks have been challenged by evolutionary and revolutionary factors which are drastically changing the traffic features. Most of these changes imply the need for major re-configurability and programmability not only in data-centers and core networks, but also in the metro-access segment. In a wide variety of contexts, this necessity has been addressed by the proposed introduction of the innovative paradigm of software-defined networks (SDNs). Several solutions inspired by the SDN model have been recently proposed also for metro and access networks, where the adoption of a new generation of software-defined reconfigurable integrated photonic devices is highly desirable. In this paper, we review the possible future application scenarios for software-defined metro and access networks and software-defined photonics (SDP), on the base of analytics, statistics, and surveys. This work describes the reasons underpinning the presented radical change of paradigm and summarizes the most significant solutions proposed in literature, with a specific emphasis to physical-layer reconfigurable networks and a focus on both architectures and devices.
Generation and Detection of Continuous Variable Quantum Vortex States via Compact Photonic Devices
Authors: Barral David , Balado Daniel , Liñares Jesús
Published: January 2017

A quantum photonic circuit with the ability to produce continuous variable quantum vortex states is proposed. This device produces two single-mode squeezed states which go through a Mach-Zehnder interferometer where photons are subtracted by means of weakly coupled directional couplers towards ancillary waveguides. The detection of a number of photons in these modes heralds the production of a quantum vortex. Likewise, a measurement system of the order and handedness of quantum vortices is introduced and the performance of both devices is analyzed in a realistic scenario by means of the Wigner function. These devices open the possibility of using the quantum vortices as carriers of quantum information.
Preparation and Characterization of Highly Aligned Carbon Nanotubes/Polyacrylonitrile Composite Nanofibers
Authors: Song Yanhua , Sun Zhaoyang , Xu Lan , Shao Zhongbiao
Published: January 2017

In the electrospinning process, a modified parallel electrode method (MPEM), conducted by placing a positively charged ring between the needle and the parallel electrode collector, was used to fabricate highly aligned carbon nanotubes/polyacrylonitrile (CNTs/PAN) composite nanofibers. Characterizations of the samples—such as morphology, the degree of alignment, and mechanical and conductive properties—were investigated by a combination of scanning electron microscopy (SEM), transmission electron microscopy (TEM), universal testing machine, high-resistance meter, and other methods. The results showed the MPEM could improve the alignment and uniformity of electrospun CNTs/PAN composite nanofibers, and enhance their mechanical and conductive properties. This meant the successful preparation of highly aligned CNT-reinforced PAN nanofibers with enhanced physical properties, suggesting their potential application in appliances and communication areas.
Hyperspectral Imagery Super-Resolution by Adaptive POCS and Blur Metric
Authors: Hu Shaoxing , Zhang Shuyu , Zhang Aiwu , Chai Shatuo
Published: January 2017

The spatial resolution of a hyperspectral image is often coarse as the limitations on the imaging hardware. A novel super-resolution reconstruction algorithm for hyperspectral imagery (HSI) via adaptive projection onto convex sets and image blur metric (APOCS-BM) is proposed in this paper to solve these problems. Firstly, a no-reference image blur metric assessment method based on Gabor wavelet transform is utilized to obtain the blur metric of the low-resolution (LR) image. Then, the bound used in the APOCS is automatically calculated via LR image blur metric. Finally, the high-resolution (HR) image is reconstructed by the APOCS method. With the contribution of APOCS and image blur metric, the fixed bound problem in POCS is solved, and the image blur information is utilized during the reconstruction of HR image, which effectively enhances the spatial-spectral information and improves the reconstruction accuracy. The experimental results for the PaviaU, PaviaC and Jinyin Tan datasets indicate that the proposed method not only enhances the spatial resolution, but also preserves HSI spectral information well.
Analysis of the Light Propagation Model of the Optical Voltage Sensor for Suppressing Unreciprocal Errors
Authors: Li Hui , Fu Zhida , Liu Liying , Lin Zhili , Deng Wei , Feng Lishuang
Published: January 2017

An improved temperature-insensitive optical voltage sensor (OVS) with a reciprocal dual-crystal sensing method is proposed. The inducing principle of OVS reciprocity degradation is expounded by taking the different temperature fields of two crystals and the axis-errors of optical components into consideration. The key parameters pertaining to the system reciprocity degeneration in the dual-crystal sensing unit are investigated in order to optimize the optical sensing model based on the Maxwell's electromagnetic theory. The influencing principle of axis-angle errors on the system nonlinearity in the Pockels phase transfer unit is analyzed. Moreover, a novel axis-angle compensation method is proposed to improve the OVS measurement precision according to the simulation results. The experiment results show that the measurement precision of OVS is superior to ±0.2% in the temperature range from −40 °C to +60 °C, which demonstrates the excellent temperature stability of the designed voltage sensing system.