bluuebunny/crossref_metadata_2025 huggingface dataset:
Phyto-Extracts and Silicone Gel (JUMI) in Reduction of Surgical Scar Post-joint Arthroplasty. A Randomized Control Trial
Authors: Sadat-Ali Mir , AlMousa Sulaiman A. , AlTabash Khalid W. , Abotaleb Mohamed M. , Al Anii Fawaz M. , AlOmran Abdallah S.
Published: April 2023

Background and Objective:

To assess the clinical potency of JUMI Anti-Scar Cream (JASC) in the prevention of excessive scar formation post total hip replacement (THR) and total knee replacement (TKR).

Patients and Methods:

Our study was an open-label, prospective, randomized control to test the efficacy of JASC. After surgery, the same material was used in both groups to close the skin. After 14 days, once the staples were removed, JASC was applied twice a day for 60 days. Patients were seen at 6 and 12 weeks. At 3-month follow-ups, the scars were assessed using the Visual Analogue Scale (VAS) and Vancouver Scar Scale (VSS).

Results:

Forty patients were part of this trial; two patients in the control group were lost during follow-up. The average age-matched in both groups. There were no adverse or untoward effects due to the use of JASC. At 3 months, there were significant differences between the parameters assessed; VAS scores were P<0.0001. VSS parameters such as vascularity, pigmentation, pliability, and scar height were much lower compared to patients who had standard treatment (P<0.0001).

Conclusion:

Our study demonstrated that JASC was effective and successful in suppressing excessive scar formation. We believe that JASC has the potential as a prime anti-scar therapy, and we recommend more multicentric studies.

Clinical Trial Rg. No: This trial was registered with the Sri Lankan Trial Registry vide #2022/021.
Antimicrobial Stewardship Program: Time to be Focused in
Speciality Settings of Leprosy Institute and Related Health Care
Setup
Authors: Thangaraju Pugazhenthan , Velmurugan Hemasri , Venkatesan Sajitha
Published: April 2023

Leprosy, often known as Hansen's disease is a contagious chronic infectious
disease caused by Mycobacterium leprae (M. leprae). Our methodology is easily repeatable
in tertiary care settings with diagnostic accuracy resources and staff capable of
building a stewardship team. Comprehensive antimicrobial policies and programmes
are required to properly alleviate the initial issue.
Spectrogram Window Comparison: Cough Sound Recognition using Convolutional Neural Network
Authors: Fudholi Dzikri Rahadian , Auzan Muhammad , Sari Novia Arum
Published: April 2023

Cough is one of the most common symptoms of diseases, especially respiratory diseases. Quick cough detection can be the key to the current pandemic of COVID-19. Good cough recognition is the one that uses non-intrusive tools such as a mobile phone microphone that does not disable human activities like stick sensors. To do sound-only detection, Deep Learning current best method Convolutional Neural Network (CNN) is used. However, CNN needs image input while sound input differs (one dimension rather than two). An extra process is needed, converting sound data to image data using a spectrogram. When building a spectrogram, there is a question about the best size. This research will compare the spectrogram's size, called Spectrogram Window, by the performance. The result is that windows with 4 seconds have the highest F1-score performance at 92.9%. Therefore, a window of around 4 seconds will perform better for sound recognition problems.
Financial Distress Prediction with Stacking Ensemble Learning
Authors: Hadi Muhammad Fadhlil , Liang De-Ron , Priyambodo Tri Kuntoro , SN Azhari
Published: April 2023

Previous studies have used financial ratios extensively to build their predictive model of financial distress. The Altman ratio is the most often used to predict, especially in academic studies. However, the Altman ratio is highly dependent on the validity of the data in financial statements, so other variables are needed to assess the possibility of manipulation of financial statements. None of the previous studies combined the five Altman Ratios with the Beneish M-Score. We use Stacking Ensemble Learning to classify crisis companies and perform a comprehensive analysis. This insight helps the investment public make lending decisions by mixing all the financial indicator information and assessing it carefully based on long-term and short-term conditions and possible manipulation of financial statements.
Implementation of Ensemble Methods on Classification of CDK2 Inhibitor as Anti-Cancer Agent
Authors: Kurniawan Isman , Anggraini Mela Mai , Aditsania Annisa , Setiawan Erwin Budi
Published: April 2023

Cancer is known as the second leading cause of death worldwide. About 7-10 million cases of death by cancer occur every year. The recent treatment to heal the cancer is chemotherapy. However, chemotherapy treatment is known to have side effects and cell resistance issues to certain drugs. Therefore, it is required to develop a new drug that can reduce the side effects and provide a better treatment effect. In general, anti-cancer drugs are developed by targeting Cyclin-Dependent Kinase 2 (CDK2) enzyme. Conventional drug design is not effective and efficient for obtaining new drug candidates because of no information about the biological activity before it is synthesized. In this study, we aim to develop a model to predict the activity of CDK2 inhibitors by using ensemble methods, i.e.,  XGBoost, Random Forest, and AdaBoost. The study was conducted by calculating several fingerprints, i.e., Estate, Extended, Maccs, and Pubchem, as feature variables. Based on the results, we found that Random Forest with Pubchem fingerprint gives the best result with the value of Matthews Correlation Coefficient (MCC) and Area Under the ROC Curve (AUC) values are 0.979 and 0.999, respectively. From this study, we contributed to revealing the potency of the ensemble with fingerprint in bioactivity prediction, especially CDK2 inhibitors as anti-cancer agents.
Sentiment Analysis Using Backpropagation Method to Recognize the Public Opinion
Authors: Wiguna I Komang Arya Ganda , Sugiartawan Putu , Sudipa I Gede Iwan , Pratama I Putu Yudi
Published: April 2023

Improve the service quality of tourism actors by conducting sentiment analysis on digital platforms owned by tourism businesses and collecting negative sentiments to improve the quality of services from companies owned by tourism businesses. The growth of the hospitality industry in Indonesia is experiencing rapid growth every year. The tourism industry, part of the hospitality industry, also does not escape the influence of positive and negative sentiments. One method to perform accurate sentiment analysis is Backpropagation Neural Network. Based on the results of tests on the neural network, the best accuracy is obtained when using one hidden layer with the first layer of 10 neurons. The learning rate is 0.000002, where the accuracy is 71.630%. More epochs do not guarantee better accuracy. Based on the results of the research that has been done, suggestions for further researchers are to analyze the review dataset processing method so that it gets a cleaner dataset and is expected to improve better accuracy.
Improving Cardiovascular Disease Prediction by Integrating Imputation, Imbalance Resampling, and Feature Selection Techniques into Machine Learning Model
Authors: Alfebi Fadlan Hamid , Anasanti Mila Desi
Published: April 2023

Cardiovascular disease (CVD) is the leading cause of death worldwide. Primary prevention is by early prediction of the disease onset. Using laboratory data from the National Health and Nutrition Examination Survey (NHANES) in 2017-2020 timeframe (N= 7.974), we tested the ability of machine learning (ML) algorithms to classify individuals at risk. The ML models were evaluated based on their classification performances after comparing four imputation, three imbalance resampling, and three feature selection techniques.Due to its popularity, we utilized decision tree (DT) as the baseline. Integration of multiple imputation by chained equation (MICE) and synthetic minority oversampling with Tomek link down-sampling (SMOTETomek) into the model improved the area under the curve-receiver operating characteristics (AUC-ROC) from 57% to 83%. Applying simultaneous perturbation feature selection and ranking (spFSR) reduced the feature predictors from 144 to 30 features and the computational time by 22%. The best techniques were applied to six ML models, resulting in Xtreme gradient boosting (XGBoost) achieving the highest accuracy of 93% and AUC-ROC of 89%.The accuracy of our ML model in predicting CVD outperforms those from previous studies. We also highlight the important causes of CVD, which might be investigated further for potential effects on electronic health records.
Monitoring the the Impacts of Climate Change and Variability on the Phenology of Natural Vegetation Using 250m MODIS-NDVI Satellite Data: Cace Study of the Dryland Ecosystem of Sokoto, North-Westrn Nigeria.
Authors: Jibrillah Abubakar Magaji , Eniolorunda Nathanial Bayode , Budah Garba Abdulmumin , Ahmad Dalhatu
Published: April 2023

Recent climate change and variability together with other anthropogenic drivers have exerted tremendous pressure on the fragile dryland ecosystem of Sokoto, North-western Nigeria. Vegetation phenology is one of the active indicators of the impacts of climate change on the ecosystem. This study aimed to monitor how the ecosystem of the area responds to the challenges associated with climate change in order to provide baseline information for policies and programmes geared towards addressing these challenges. It explored the applications of remote sensing data (MODIS-NDVI), GIS and statistical analyses in achieving this aim. Image processing operations such as data extraction, raster calculations, geometric transformations and creation of the region of interest were conducted using ArcGIS 10.5 model builder while TIMESAT software was used determined the vegetation phenological events such as the start, end and length of the growing seasons. The results indicated a persistent decline in the length of the growing seasons of the major vegetation classes in the area due to late onset and early cessation of the growing season which is positively correlated with rainfall distribution. From the year 2001 to 2016, 36% and 33% declined in the length of the growing season were recorded for shrubs and grasses respectively. These are positively correlated with the annual rainfall distributions in the area, with the correlation coefficient of r = 0.40 and r = 0.36 for the shrubs and grasses respectively. Implications of these on the ecosystem and livelihoods of the people in the area were discussed and ways forward suggested.
Groundwater Chemistry Characterization in the South and Southeast Merapi Volcano, Indonesia
Authors: Hendrayana Heru , Harijoko Agung , Riyanto Indra Agus , Nuha Azmin , Ruslisan Ruslisan
Published: April 2023

Merapi Volcano, which differs from volcanoes in other climates due to its location on the Indonesian Maritime Continent influenced by ENSO, ICTZ, and Moonsons, plays an essential role as a source of groundwater for the surrounding population. Some problems associated with groundwater in Mount Merapi are high utilization compared to other volcanoes worldwide, changes in land use, pollution, and its lowering table. Therefore, this study aims to compare the hydrogeological characteristics and aquifer systems of the southern and southeastern parts of Merapi Volcano. The hydrogeological characteristics were obtained from geological mapping, surface and subsurface, as well as rock XRF tests. Meanwhile, the hydrogeochemical characterization was determined through chemical data using the Trilinear Piper, Kurlov, Fingerprint, Composition, and Harker Diagram methods. The results of the Trilinear Piper, Kurlov, Fingerprint, and Composition Diagram methods show that Mount Merapi has 3, 7, 4, and 2 types of patterns different from other volcanoes in the world. On the other hand, the Harker diagram has the same pattern of Mg-Ca and Mg-Na as several other volcanoes. In conclusion, the hydrostratigraphy in the southern part of the volcano, consists of aquifuge, aquiclude, and aquifer, while in the southeast, there are aquitards of volcanic sandstone and tuff.
Cultural Ecology and Environmental Education: Lesson Learned from Baduy Indigenous Community
Authors: Waluya Bagja , Malihah Elly , Ruhimat Mamat , Wiyanarti Erlina
Published: April 2023

This research investigated culturally-generated abilities and skills in the frame of human adaptation and environmental education. Under qualitative approach, this research implemented phenomenological research method that seek to understand the situation that occurs locally to certain group. Data collection was done through observation and interview with four key informants involving indigenous community leaders, community members, and formal education practitioner. Additional informants were taken from snowball sampling technique from whose accounts were elaborated until data saturation achieved. Validity and reliability of data were carried through member check and data triangulation. Data analysis process follow three sequential phases, namely data reduction, display, and drawing conclusion. Findings of research were grouped into three sections, namely a) cultural ecology of Baduy indigenous community; b) environmental education based on local wisdom of Baduy people; and c) pedagogical experience on local wisdom-based learning.
Efectos de la Socialización Organizacional en la Salud Mental Positiva en el Trabajo
Authors: Calderón Mafud José Luis , Pando Moreno Manuel , Aranda Beltrán Carolina
Published: April 2023

La salud mental positiva en el trabajo explica el estado de bienestar que un individuo puede desarrollar en su respectiva organización y que le permite poseer una vida plena. Este artículo presenta los resultados de una investigación realizada para identificar los efectos de la socialización organizacional en la salud mental positiva en el trabajo. Se analizó una muestra de 389 participantes, a quienes se evaluó mediante el Inventario de Socialización Organizacional y el Cuestionario de Salud Mental Positiva en el Trabajo-40, en sus versiones en español. Los resultados indicaron que la socialización organizacional tuvo correlaciones positivas (.39, .23, .38 y .43), respectivamente con los componentes espiritual, cognitivo, conductual y socioafectivo de la Salud Mental Positiva en el Trabajo. Mediante el análisis de regresión se encontraron efectos combinados de los dominios de socialización organizacional en el factor socioafectivo de la salud mental positiva en el trabajo. Por ende, se discuten sus efectos y se realizan recomendaciones para realizar intervenciones.
Diferencias del riesgo de violencia en adolescentes según la densidad de población
Authors: Granados Muñoz Rolando
Published: April 2023

El estudio de la violencia y/o el crimen con la densidad de población se ha venido investigando a lo largo del tiempo afirmando que existe una relación. Con el objetivo de explorar diferencias significativas del riesgo de violencia en adolescentes según la densidad de población, se aplicó la Escala de Valoración del Riesgo de Violencia en Adolescentes por medio de la técnica de encuesta a 652 estudiantes de cuatro ciudades de Guanajuato, México. La hipótesis planteada afirma que a mayor densidad de población mayor será el riesgo de violencia en adolescentes. Los resultados encontrados indican que existen diferencias significativas entre la segunda ciudad con mayor densidad de población, reportando los niveles más bajos del riesgo de violencia respecto a las demás, las ciudades en los lugares tres y cuatro en razón de su densidad de población reportan mayores niveles de riesgo de violencia. Estos hallazgos hacen rechazar la hipótesis planteada y estar en disimilitud con otros estudios que se han realizado, la explicación de dichas diferencias entre los resultados puede estar orientada a que las metodologías empleadas y las variables estudiadas se deben a los objetivos que se pretenden.
Family Strengths, the Circumplex Model of Family Systems, and Personal and Family Functioning: A Meta-Analysis of the Relationships Among Study Measures
Authors: Dunst Carl Joseph
Published: April 2023

Findings from a meta-analysis of studies investigating the relationships between family strengths and personal and family well-being and functioning are reported. The research synthesis included 33 studies conducted in six countries of 8259 study participants. The Family Strengths Scale developed by David Olson and his colleagues was used to measure family strengths. The studies included five personal functioning measures (depression, loneliness, stress, well-being, & belief appraisals) and five family functioning measures (communication, cohesion, flexibility, marital satisfaction, & stress). The correlations between family strengths and personal and family functioning were used as the effect sizes for the relationships between measures. Results showed that family strengths were related to each of the personal and family functioning measures, there were no differences in the sizes of effect between either the five personal functioning or the five family functioning measures, and that the size of effect for the relationship between family strengths and family functioning was nearly twice as large as the size of effect for the relationship between family strengths and personal functioning. Findings showed that family strengths were related to other family systems constructs in an expectant manner and that family strengths were related to different dimensions of healthy personal and family functioning as hypothesized. The results are discussed in terms of the how family strengths are important beliefs and practices for explaining healthy personal and family functioning. Five different limitations are also described.
Comunicación sobre sexualidad en padres de jóvenes sordos
Authors: Bárcena Goana Susana Xóchitl , Enríquez Negrete David Javier , Sánchez Medina Ricardo
Published: April 2023

Esta investigación tuvo como objetivo identificar las variables que promueven y limitan la comunicación sobre sexualidad en padres de jóvenes sordos, así como el papel que desempeña la modalidad comunicativa y el género de quienes conforman la díada padre-hijo. Se trabajó con una muestra no probabílistica de 79 padres a quienes se les aplicó un instrumento de autoinforme para conocer sus características sociodemográficas y las de sus hijos, sus creencias sobre sexualidad, roles de género, expectativas, autoeficacia, comunicación sobre sexualidad, modalidad comunicativa y percepción del dominio de la Lengua de Señas Mexicana (LSM). Los resultados más importantes de esta investigación sugieren que el género juega un papel importante tanto en las expectativas como en la comunicación sobre sexualidad. El hecho de que los padres tengan el mismo género que sus hijos, favorece que no tengan expectativas negativas hacia la comunicación sobre sexualidad y también que aborden temas que suelen resultar incómodos como la masturbación y el cómo usar condón. Se discuten las implicaciones de los resultados de esta investigación en el diseño de programas de intervención dirigidos a esta población.
Propiedades Psicométricas del Cuestionario de Normas Sociales Alimentarias en el Noreste de México
Authors: Pérez Pedraza Bárbara de los Angeles
Published: April 2023

Con el objetivo de construir y validar un cuestionario que mide las normas sociales alimentarias (NSA) en escolares, se realizó un estudio instrumental y transversal. Mediante un muestreo aleatorio, se seleccionaron 494 niños de escuelas primarias. Se les aplicó un cuestionario validado por jueces para medir las NSA. En el análisis exploratorio se encontraron dos factores que explican el 27.85% del constructo: normas para reproducir (α=.774, r2=.893, p=.001) y normas para evitar (α=.446, r2=.729, p=.001), demostrando confiabilidad (α=.762, r2=.892, p=.001) de la prueba total. El análisis confirmatorio mostró que el modelo bifactorial presentó una mejor bondad de ajuste (GFI=.951, RMSEA=.059) que el modelo unifactorial (GFI=.943, RMSEA=.096). El cuestionario de la NSA compuesto por dos factores es válido y confiable para la población de niños en edad escolar en el noreste de México.
Léon Prunier
Authors: Wisniak Jaime
Published: April 2023

Léon Prunier (1846-1906), a French pharmacist and physician, who studied the synthesis of polypropylene hydrocarbons by the reaction of propylene bromide with nascent hydrogen prepared by different means, and the synthesis of ethylene acetylene; proving that the latter was identical with crotonylene. Together with R. David they synthesized a variety of high melting point unsaturated hydrocarbons by the pyrolysis of American petroleum. His main contribution was the study of quercitol, its preparation by means of lead acetate, its physical and chemical properties, as well as its reaction with a wide range of chemicals. He proved that the thermal decomposition of quercitol at high temperatures led to synthesis of aromatic compounds, among them, hydroquinone, quinhydrone, and benzene.
Diversidad y bioactividad de análogos semisintéticos de cannabidiol
Authors: Musso Florencia Antonella
Published: April 2023

La especie vegetal Cannabis sativa (Cannabaceae) posee importantes propiedades medicinales gracias a los componentes bioactivos que posee. El fitoestrógeno CBD se puede encontrar en la planta y debido a las características terapéuticas y estructurales de la molécula, lo convierte en un interesante andamio susceptible a numerosas modificaciones sintéticas, con el fin de mejorar su eficacia y potencia terapéutica. Este trabajo proporciona información sobre los distintos análogos sintéticos de CBD descubiertos en los últimos años (2010 - 2021). La búsqueda bibliográfica se realizó en distintas bases de datos, con distintas palabras clave. Dicha búsqueda se limitó a los años 2010 - 2021, y se consideraron revisiones, micro revisiones y meta-análisis de mayor impacto. Se recopilaron alrededor de 40 nuevos análogos sintéticos de CBD y fueron clasificados según el blanco estructural modificado. Estos compuestos poseen una importante bioactividad e incluso, muchos conservan la actividad de su precursor. Sin embargo, en muchos casos, el conocimiento de su mecanismo de acción aún se encuentra en estudio por lo que se necesitan numerosas investigaciones farmacológicas y medicinales.
Preparación de un barniz basado en residuos poliméricos como complemento experimental para estudiantes de ingeniería
Authors: Taverna María Eugenia , Boriglio Rocío , Dobler Santiago , Lesta Mateo , Scocco Nazareno , Garnero Paula Carolina
Published: April 2023

En el presente trabajo se presenta el desarrollo y los resultados de una experiencia destinada a la enseñanza de la química en las cátedras de Ingeniería y Ciencia de los materiales y Polímeros de la carrera de Ingeniería Química. La experiencia consistió en la elaboración de un barniz a partir de residuos de poliestireno expandido. Este enfoque tiene relación con el cuidado medioambiental y la reutilización de los residuos poliméricos en el desarrollo de productos de valor agregado. Este trabajo se llevó a cabo durante el trascurso del año lectivo 2022 en diferentes encuentros. Las tareas se realizaron en conjunto con estudiantes avanzados de Ingeniería Química a fin de complementar la actividad experimental e incorporar conceptos sobre polímeros, soluciones, propiedades de materiales, entre otros. Los principales resultados muestran que es posible obtener barnices basados en poliestireno expandido recuperado, con precios competitivos y propiedades aceptables, y que los estudiantes logran mediante estas experiencias fortalecer sus conocimientos en el área de polímeros, y sensibilizarse en la importancia del cuidado del medio ambiente.
Gene Sequencing of Hepatitis C Virus Isolated from Patients with Liver Diseases
Authors: Zghair Abdulrazzaq N. , Mohammed Nazar Sh. , Kasim Sumayah Faruq
Published: April 2023

Infection with the hepatitis C virus (HCV) is serious and may lead to death. Venous blood samples were collected from HCV-infected patients (n=60) and from people without infection (n=60) as controls. These patients visited the Digestive System and Liver Disease Hospital, Baghdad, Iraq, during the period from 1st February to 1st November 2021. The results revealed no significant difference between males (31; 50.8%) and females(29; 49.2%) HCV-infected patients. The highest infection rate (55.6%) was observed among the 50–78 years age group, then 53.7% among the 25–49 years age group, then 36.7% among the 5–24 years age group with a significant difference (P=0.2). A highly significant difference was observed in the mean glutamic-pyruvic transaminase levels between HCV-infected patients (25.56±12.45) and the controls (17.86±4.91) (P=0.01), and a significant difference was observed in the mean glutamic-oxaloacetic transaminase levels between HCV-infected patients (21.70±8.63) and the controls (15.93±4.35) (P=0.02). A highly significant difference was demonstrated in mean alkaline phosphatase levels between HCV-infected patients (362.15±113.60) and controls (197.81±34.70)(P=0.001). Overall, we found that blood markers could aid in disease diagnosis and prognosis rather than mutations within the nonstructural 5A.1 hot spot. The frequency of mutations within this site was found to be very low.
Antimicrobial Activity and Multi-therapeutic Potential of Salvia officinalis and Mentha longifolia Essential Oils in Leaves
Authors: Bukhari Duaa Abdulrashid A.
Published: April 2023

The objective of the current work was to test the antimicrobial impact of Salvia officinalis and Mentha longifolia collected from Al-Madinah city in Saudi Arabia and extracted by hydrodistillation versus Escherichia coli (ATCC25922), Enterobacter cloacae (ATCC13047), Candida tropicalis (ATCC 13803), and Aspergillus fumigates (ATCC46645). M. longifolia essential oils showed higher inhibition zones versus tested microorganisms, especially against E. coli and C. tropicalis. Minimal inhibitory concentrations of M. longifolia essential oils were determined for M. longifolia, where 3.9 and 62.5 µg/ml were the resulted values of the essential oils versus E. coli and C. tropicalis, respectively. Antioxidant impact of essential oils from both plants was compared using a DPPH assay where, M. longifolia showed the most promising antioxidant action with an IC50 of 88.73 ± 2.59 µg/ml. Transmission electron microscopic examination was applied after treatment of E. coli and C. tropicalis using M. longifolia essential oils, which showed their impact to destroy tested bacterial and fungal microbes as standard drugs. M. longifolia essential oils were further tested versus colorectal cancer cells, showed their cytotoxic impact versus cancer cells with an IC50 of 97.61 ± 1.8 μg/ml and confirmed by flow cytometric analysis, which showed that treated cells by M. longifolia essential oils dramatically elevated their apoptotic rate (P< 0.05) compared to untreated Caco-2 cells. M. longifolia essential oils showed minimal cytopathic action versus Vero cells, which revealed their potency. These results illustrated the possible pleiotropic experimental roles of M. longifolia growing in Al-Madinah City to be applied in pharmaceutical applications after in vivo confirmation of results.
Association Between Gonococcal Infection and a Common Genetic Deletion in Sperm Mitochondrial
Authors: Kadhim Mohanad Jawad , Hasson Shaimaa Obaid , Al-Janabi Hayder Shkhair
Published: April 2023

Neisseria gonorrhoeae is a member of the Neisseriaceae family. They are non-spore-forming, gram-negative, encapsulated, non-motile, non-acidic, and bean-shaped bacteria. This study included 40 men that presented chronic and recurrent infection with N. gonorrhoeae virus. The initial infection of this virus was detected using a rapid bacterial antigen immunoassay and confirmed using enzyme-linked immunosorbent assay (ELISA ). The mean age of the study group was 36.71±12 (mean±) years. Men between the age of 20-49 years were the most affected by N. gonorrhoeae infection, and displayed a significantly lower average sperm count than the healthy individuals upon semen examination. The percentage of sperms with slow motility, total number of dead sperms, and abnormal- shaped sperms were some significant phenotypes observed in the infected individuals as compared to that in the healthy controls. In this study, we found that the bacterium, N. gonorrhoeae could cause erosion of the mitochondrial DNA of sperms in the semen of the infected individuals. In addition, using the gap-PCR technique, it became evident that the infected individuals portraying altered sperm characteristics as mentioned above, showed increased number of common deletion (4, 977 base pairs) in the sperm mitochondrial (mt)-DNA. Hence, our results imply that N. gonorrhoeae infection can lead to a common deletion of 4,977 bp in sperm mt–DNA, which can in turn cause male sterility.
Isolation of Fungi from Mangrove Ecosystem of Mumbai and Evaluation of their Antibacterial Potential
Authors: Patankar Rutuja Sunil , Reshi Nissar Ahmad
Published: April 2023

In the current study, fungi from the mangrove ecosystem of Mumbai were isolated and their metabolites were screened for antibacterial potential. Two weeks old broth and mycelium were extracted using chloroform and methanol. Antibacterial property of solvent extracts was evaluated at various concentrations (2 – 10 µg/ml) against Staphylococcus aureus, Bacillus subtilis, Enterococcus faecium, Enterococcus faecalis, Klebsiella pneumonia and Escherichia coli, by well diffusion method. Fungi isolated were identified as Aspergillus niger, Aspergillus flavus, Trichoderma harzianum, Cylindrocladium scoparium and Colletotrichum wuxiense. Results revealed that broth solvent extracts of isolates inhibited the growth of all gram-positive test bacteria, chloroform broth extract of Cylindrocladium scoparium, Colletotrichum wuxiense and ethanolic broth extract of Aspergillus flavus, Trichoderma harzianum exhibited antibacterial potential against gram negative test organisms. Chloroform and ethanol mycelium extracts of Trichoderma harzianum and Aspergillus flavus, respectively, exhibited 100% growth inhibition potential against all test organisms. The current investigation endorses the potent secondary metabolism of the identified isolates and their potential to synthesise antibacterial compounds.
A Review on Basalt Fiber and Basalt Fiber Reinforced Polymer Composites: Advancement and Industrial Applications
Authors: Mundhe Gajanan S. , Mahanwar Prakash A. , Patil Jayesh R. , S Elamaran
Published: April 2023

Abstract: Basalt fiber is a type of mineral fiber that is derived from basalt rock. It has excellent mechanical properties, high resistance to chemicals, superior thermal stability, and good resistance to moisture. Additionally, it is environmentally friendly as it can be easily recycled. All these properties are better when compared to E-glass, which uses many industries for structural applications. The use of basalt fiber reinforced composites (FRC) in industries is still limited because there isn't enough information available about them and their production is not yet at a large scale. This makes them more expensive to produce, which reduces their adoption in industrial applications. This paper critically evaluates the current knowledge and understanding of basalt FRC and highlights the growing interest in researching and publishing articles related to basalt composites. In addition to reviewing the current state of knowledge on basalt fiber reinforced composites, this paper also shares information about the physical, chemical, and mechanical properties of basalt fibers. It also includes some data on the environmental impact of producing basalt fiber reinforced composites and reviews the typical industrial applications where they can be used.
Pengaruh Proporsi Penambahan Pati Ganyong (Canna edulis Ker.) Terhadap Sifat Fisiko Kimia Serta Tingkat Kesukaan Cookies
Authors: Rosania Sephina Putri , Sukardi Sukardi , Winarsih Sri
Published: April 2023

Pengembangan diversifikasi pangan berbasis bahan pangan lokal terutama umbi-umbian dinilai mampu meningkatkan nilai jual bahan pangan. Salah satu bahan pangan yang masih kurang dalam pemanfaatannya ialah umbi ganyong. Melihat potensi umbi ganyong yang sangat melimpah di Desa Taji dan kurangnya pengolahan lebih lanjut pada umbi ganyong menyebabkan nilai jual ganyong yang relatif rendah. Ganyong umumnya langsung dikonsumsi setelah direbus atau dikukus tanpa ada pengolahan lainnya. Salah satu pengolahan ganyong yang dapat dilakukan adalah dengan pembuatan pati. Pati ganyong berpotensi digunakan menjadi bahan substitusi olahan pangan salah satunya ialah cookies. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan pati ganyong terhadap sifat fisiko kimia pada cookies. Kandungan amilopektin yang cukup tinggi mampu mempertahankan tekstur cookies. Kadar lemak pati ganyong yang relatif lebih rendah mampu mengurangi kadar lemak didalam cookies. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) sederhana dengan menggunakan 1 (satu) faktor yaitu substitusi pati ganyong serta tepung terigu yang terdiri dari 5 level (10% : 90%; 30% : 70%; 50% : 50%; 70% : 30%; 90% : 10%) dan perlakuan kontrol dengan penggunaan 0% pati ganyong. Dari faktor tersebut didapatkan total 5 perlakuan dengan 3 ulangan percobaan. Data dianalisis dengan menggunakan Analysis of Variance (ANOVA) dan dilanjutkan uji banding Duncan’s Multiple Range Test (DMRT). Hasil penelitian menunjukkan bahwa terdapat pengaruh substitusi pati ganyong terhadap kadar air, kadar abu, kadar protein, kadar lemak, kadar karbohidrat, daya patah, intensitas warna, dan organoleptik cookies. Cookies pati ganyong terbaik terdapat pada perlakuan P2 (Pati ganyong 30% : tepung terigu 70%) dimana memiliki kandungan kadar air sebesar 2,77%, kadar abu sebesar 0,85%, kadar lemak sebesar 30,06%, kadar protein sebesar 7,22%, dan kadar karbohidrat sebesar 59,10%.  Nilai daya patah sebesar 35,53 N/mm, pengujian tingkat kecerahan 70,83 L. Hasil organoleptik warna  5,2 (agak cerah), aroma 6,2 (tidak beraroma pati), tekstur 5,2 (renyah), rasa 5,8 (manis), dan tingkat kesukaan 6,4 (suka).
Penerapan Hazard Analysis Critical Control Point (HACCP) Pada Proses Produksi Hot Meal Dori Woku Belanga Untuk Maskapai Garuda Indonesia di PT. Aerofood ACS Denpasar
Authors: Nanda Sahrevi Aulia Shalsabilla , Wijayanthi Desak Gede Putri , Anggriani Rista
Published: April 2023

Aerofood ACS Denpasar merupakan salah satu perusahaan yang bergerak dalam bidang catering untuk maskapai penerbangan. Inflight catering melayani produk makanan yang disajikan selama perjalanan dalam penerbangan. PT. Aerofood ACS Denpasar telah menerapkan HACCP (Hazard Analysis and Critical Control Point). HACCP menjadi jaminan bahwa produk sudah sesuai dengan standar internasional. Proses produksi hot meal dori woku belanga di PT. Aerofood ACS Denpasar dimulai dari penerimaan bahan baku pada bagian receiving, penyimpanan (storage), thawing, cooking, blast chilling, dishing and portioning, dan final holding sebelum makanan siap diantarkan ke pesawat. Selama proses produksi diterapkan sistem HACCP untuk membantu menjaga kualitas makanan. Terdapat 5 Critical Control Point pada proses produksi hot meal dori woku belanga yaitu receiving (chilled and frozen), storage (cold storage), cooking, blast chilling, dan dishing & portioning. Di setiap titik kritis ini, memiliki suhu kritis standar berbeda-beda.
Cryptocurrency assets as a physical collateral in Indonesia
Authors: Wardoyo Yohana Puspitasari , Hapsari Dwi Ratna Indri
Published: April 2023

Cryptocurrency investment is currently expanding quickly on a global scale as well as in Indonesia. On the one hand, cryptocurrency can be used as a medium of exchange or a form of money, which represents the original purpose of cryptocurrency. On the other hand, it can also be used as a commodity or as digital assets, also known as crypto assets. Cryptocurrency is illegal to use as money in Indonesia, but it is legal to exchange it as an asset. This study explores the legal protections for holders of collateral against the loss of crypto assets as well as how crypto assets are governed by material guarantees in Indonesia. A conceptual and statutory approach, technical analysis, and a normative legal research methodology were applied in the study. The legal material was analyzed by using the content analysis approach, which involved examining the content and legality of the material gleaned from various laws and regulations by looking at the relevant legal precedents. The discussion results discover that crypto assets fall under the definition of "intangible movable objects" as defined in article 503 BW. In addition, crypto assets had material rights in the form of material guarantees in the form of a pledge and fiduciary guarantees, allowing the parties to carry out their agreements in good faith even in the event that the collateral object is lost. These disputes could be settled through either non-litigation or litigation.
Islamic nomocracy: from the perspectives of Indonesia, Spain and Russia
Authors: Wibowo Sugeng , Dimyati Khudzaifah , Absori Absori , Wardiono Kelik , Ramon Tomás Mateo , Budiono Arief , Lyandova Vanka
Published: April 2023

The Indonesian Islamic nomocracy paradigm has a long history and a cultural relationship with the national struggle that coincides with political and religious orientations. The Islamic nomocracy is inseparable from the relationship between Islam and the state rather than being linked to Islamic doctrine and power. This research employed the normative sociological method. It used a philosophical approach from Barbour’s paradigm of the relationship between religion and science and Habermas’ thought on religion in public spaces. This research strives to analyze the Islamic nomocratic paradigm pattern prior to Indonesian independence as a crucial stage that influences the following eras, namely the post-independence era, the Old Order Era, the New Order Era, and the Post-Reformation era up to now. This research aims to find the basics and the development of the Islamic nomocracy in the Indonesian legal system. The roots of the Islamic nomocracy legal thought in Indonesia can be traced to the pre-independence era. In the development of Islamic kingdoms, there was a dialog and integration process between the Islamic nomocracy and the kingdom government. After the War of Java, the conflict and independence pattern was formed. Before Indonesian independence, the Islamic nomocracy thought developed into Pan Islamism which tended to be conical to legal formalization through the caliphate system. After Indonesia’s independence, some of the Islamic nomocracy legal thought recognized the state as one of the legal systems in Indonesia besides customary law and positive law. Then, Indonesia became a partly-Islamic Legal State with a constant up-and-down relationship with the state. The authors also completed this paper with perspectives of Spain and Russia as both have been ruled under Muslim governance.
Las voces que hablan en el periodismo científico: tipo de fuentes y temáticas que se presentan en la prensa escrita chilena
Authors: Martin-Neira Juan-Ignacio
Published: April 2023

La presente investigación da cuenta cómo la prensa escrita chilena ha publicado noticias asociadas a la ciencia y tecnología en los últimos años, analizando las fuentes que se usan y las temáticas que se plantean, haciendo un paralelo de lo que se informaba pre y post pandemia. Los resultados reflejan que hubo una disminución de noticias científicas entre los meses de enero del 2020 y enero del 2021, y que, además, el coronavirus se tomó las pautas informativas de los principales diarios de Chile.
Otra mirada docente hacia la discapacidad
Authors: Simón Medina Natalia , Del Valle Díaz Sagrario , De Cisneros De Britto Julio César , Rodríguez Torres Javier
Published: April 2023

Los postulados postmodernos requieren que el docente se adapte a una sociedad que cambia vertiginosamente formando parte de una escuela inclusiva. El objetivo de esta investigación es examinar las actitudes hacia las personas con discapacidad del docente de educación Infantil, Primaria y Secundaria comparando las diferencias existentes, además, en función de sus características personales (sexo, edad, tipo de centro, etapa educativa y años de experiencia docente) y analizando cómo los factores que integran la escala se relacionan con determinadas variables conexas con la discapacidad (contacto con personas con discapacidad, tipo de contacto, frecuencia del contacto, sentimiento ante personas con discapacidad y nivel de información percibido sobre discapacidad). La muestra está formada por un total de 1431 docentes. Los datos obtenidos de la Escala de Actitudes hacia las Personas con Discapacidad de Arias et al. (2016) utilizada se han analizado a partir de un análisis bivariante a través de pruebas t de igualdad de medias. Entre los resultados obtenidos destaca el hecho de tener contacto con personas con discapacidad, sentir que se está bien informado sobre la discapacidad, y sentirse cómodo con personas con discapacidad ya que se relacionan con una actitud más positiva hacia las personas con discapacidad en contraposición a los docentes que no tienen contacto, que se sienten poco informados y menos cómodos con personas con discapacidad.
gran transformación del poder económico: puertas giratorias, capital y consejeros en la red de empresas españolas cotizadas
Authors: Juste de Ancos Rubén
Published: April 2023

Este trabajo analiza la cohesión del poder económico. Se parte de la hipótesis de un poder económico cohesionado por elementos políticos, sociales y económicos, como las puertas giratorias entre Estado y empresas, y las relaciones entre diferentes empresas a partir de miembros de consejos de administración y accionistas compartidos entre sí. Para comprobar dicha hipótesis se ha seleccionado una muestra con las treinta cinco empresas españolas que componen el índice bursátil IBEX35 en cuatro periodos diferentes  (1991, 2000, 2010, y 2013). La metodología de análisis de redes sociales se ha aplicado en este estudio para analizar divisorias y factores de cohesión dentro del poder económico en los diferentes años seleccionados. Esta investigación muestra la importancia de la crisis económica de 2008, tras la cual se reducen los vínculos políticos entre empresas y hay un descenso del número de consejeros que pertenecían simultáneamente a varios consejos de administración. En contraposición, los accionistas y, en concreto, el capital internacional, se convierte en el principal elemento de intermediación entre el conjunto de empresas, en detrimento de los lazos políticos y corporativos que habían dominado en anteriores periodos.
Sobreeducación y preferencias políticas: efectos del desajuste entre educación y empleo sobre el posicionamiento ideológico, el radicalismo y el voto a izquierda y derecha
Authors: Caínzos Miguel , Voces Carmen
Published: April 2023

El artículo estudia la relación entre experiencia de sobreeducación y preferencias políticas en España, un país caracterizado por una alta tasa de sobreeducación. Usando datos de dos encuestas postelectorales, estimamos Modelos de Referencia Diagonal para contrastar hipótesis acerca de los efectos del desajuste entre educación y empleo sobre el posicionamiento ideológico, el radicalismo y el voto a izquierda y derecha. Encontramos indicios de que la sobreeducación está asociada a posicionamiento más a la izquierda y a mayor probabilidad de votar a partidos de izquierda. Los efectos son modestos y están moderados por la edad: solo se encuentran para los trabajadores más jóvenes. Esto podría ser debido a razones contextuales (en España, el discurso público sobre la sobreeducación la ha presentado como un problema de los jóvenes) o a factores estructurales (la inconsistencia de estatus solo es políticamente relevante en la medida en que el grado de cristalización estructural de las posiciones de estatus es bajo).
Miedos e inquietudes ante la pandemia en España: un análisis exploratorio de las desigualdades sociales
Authors: Domínguez-Rodríguez Antía
Published: April 2023

La crisis ligada al Covid-19 ha impactado en la sociedad española modificando sus hábitos y costumbres. La sociedad muestra unas expectativas de futuro que se transforman en miedos y temores ante qué pasará en el futuro en distintos aspectos. En este estudio se busca profundizar en estos miedos y evaluar las desigualdades sociales que se presentan en el padecimiento de los mismos, a través del análisis de tres encuestas del CIS de “Efectos y consecuencias del coronavirus”, para octubre de 2020, septiembre de 2021 y diciembre de 2021. Los resultados muestran una mayor prevalencia de los miedos sociales frente a los económicos, aunque es en estos últimos donde se encuentran las principales diferencias significativas según nivel educativo, edad y lugar de nacimiento. Además, son las mujeres las que se muestran más preocupadas. Será necesario esperar a ver cómo se desenvuelve la crisis para evaluar cómo evolucionan estos miedos.
Perfiles negacionista y antivacunas entre la población española
Authors: López Rey María José
Published: April 2023

Este trabajo focaliza su interés en los discursos negacionistas en torno a la pandemia de COVID 19, atendiendo especialmente a la población cuya preocupación por la pandemia es nula o casi nula y aquella otra reticente a la vacunación. El objetivo específico es cuantificar y caracterizar el colectivo que suscribe estos discursos, identificando sus características sociodemográficas para ponerlas en relación con las bases sobre las que articulan su argumentación. Para la consecución de este objetivo proponemos un ejercicio de triangulación metodológica, conjugando datos primarios y secundarios que se analizan con técnicas cuantitativas de investigación. Los datos primarios se obtienen de una encuesta, realizada sobre una muestra de la población española adulta. Los datos secundarios provienen de diversas fuentes de información, principalmente los barómetros del CIS, y complementan estos datos secundarios los procedentes de otros estudios como el promovido por la FECyT, sobre las actitudes ante la vacunación, realizado en junio de 2020, o el estudio de monitorización de los comportamientos de la población ante la pandemia que pone en marcha la OMS.
Oportunidades de inclusión en escuelas con alta diversidad cultural. Un estudio etnográfico
Authors: Vigo-Arrazola Begoña , Dieste Belén , Blasco-Serrano Ana Cristina , Lasheras-Lalana Pilar
Published: April 2023

Cuando la perspectiva de la educación inclusiva, desde el marco de la UNESCO, ha supuesto cambios significativos en las políticas educativas, este trabajo pretende investigar cuáles son los discursos y las prácticas llevadas a cabo por el profesorado en escuelas con un alto porcentaje de minorías y población extranjera. Se trata de una etnografía multisituada, basada en la observación participante, entrevistas y análisis de documentos en tres escuelas urbanas y una pequeña escuela rural de Aragón. Los resultados muestran discursos y prácticas de enseñanza y aprendizaje que posibilitan la participación de todos los alumnos, en línea con los principios de la educación inclusiva. Sin ignorar la existencia de tensiones en torno a las políticas de inclusión, el artículo destaca el valor de tales prácticas. Asimismo, argumenta que la agencia de estos profesores implica resistencia en un contexto que ha normalizado la exclusión de estas escuelas.
Asbel Bohigues. Élites, radicalismo y democracia. Un estudio comparado sobre América Latina. Centro de Investigaciones Sociológicas (CIS), Madrid, 2021.
Authors: Turiño González Emma
Published: April 2023

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