bluuebunny/crossref_metadata_2025 huggingface dataset:
PERAN BADAN NARKOTIKA NASIONAL DALAM INTERVENSI BERBASIS MASYARAKAT UNTUK MENGURANGI PENYALAHGUNAAN NARKOBA (Studi Deskriptif Pada Remaja di Desa Pesanggrahan Kota Batu)
Authors: Fitria Rahma Icha , Sidiq Mahfudz , . Arif , Santoso Budhy , Nugroho Puspito Agung Nugroho Puspito
Published: December 2023

The problem of drugs has become a global issue and is a problem in many countries. This shows that drug crime has become a transnational and dangerous activity. The condition of drug abuse and illicit trafficking has now penetrated to the rural level, and has even spread to remote villages. With a government program that focuses on the welfare of rural communities and has an impact on improving the village economy, it turns out that the village is a potential market for drug dealers. This study aims to determine the role of the National Narcotics Agency in reducing Drug Abuse through Community-Based Interventions. This research uses descriptive research type and qualitative research approach. Determination of the research location using a purposive area technique. The technique of determining the informants used purposive sampling. Data collection techniques were carried out using observation, interviews, and documentation. Techniques for systematic data analysis are data collection, data reduction, data display, conclusion drawing, and verification. In this study, researchers used the technique of data validity triangulation of sources The results showed that the role of the National Narcotics Agency in Reducing Drug Abusers through Community-Based Interventions included: 1. The National Narcotics Agency played a role in the initial formation of the Community-Based Intervention Program, 2. The National Narcotics Agency played a role in providing assistance to face various obstacles, 3 The National Narcotics Agency plays a role in facilitation, namely providing motivation and support, 4. The National Narcotics Agency plays a role in initial monitoring and final monitoring to record weaknesses and problems encountered, 5. The National Narcotics Agency plays a role in evaluation to find out whether the program or activity is achieving results desired or not as a consideration in making decisions regarding program planning and program implementation.
„Usieciowienie” versus psychologia. Kilka uwag na temat książki Agnieszki Ogonowskiej „Cyberpsychologia. Media — użytkownicy — zastosowania”, Kraków 2021
Authors: Grodź Iwona
Published: December 2023

The reviewed publication is the result of many years of research by the author of Cyberpsychologia, Agnieszka Ogonowska, on the psychological aspects of “networking” of a person and his environment, understood not so much in the quantitative sense (time spent using the Internet) but in the qualitative sense (type and level of advancement of participation in virtual life). The texts collected in this book are the result of conferences, training and scientific meetings, so it is easy to see the multitude of perspectives on the phenomenon of cyberpsychology, and even more broadly, cyberculture. This is an undoubted advantage of this publication, because it reveals the need to have interdisciplinary competences, also in the context of the prospect of further research on the interpenetration of technology and psychology.

The findings of the author of Cyberpsychologia, which are an important reason why this book is worth recommending, must be precisely said that only the mind of a conscious, attentive sender and recipient encodes all information "here and now", does not try to hastily evaluate it or even name it, only focuses on them and analyzes them from a distance.
Oswajanie starości w „Gangu zielonej rękawiczki”
Authors: Piechota Dariusz
Published: December 2023

The Green Glove Gang is an interesting series due to its numerous references to other cultural texts. Intertextuality is revealed on many levels of Tadeusz Śliwa’s production. The protagonists resemble American superheroes (but also the protagonists of Sylwia Chutnik’s novel Cwaniary [The Hustlers]) fighting to defend the defenceless and the marginalised. The interventions they undertake are a clear exemplification of the problems faced by elderly people exposed to dishonest entrepreneurs, pawnshop owners or self-proclaimed healers. Śliwa’s series is an important contribution to the discourse on the place and role of pensioners in today’s consumerist world. The showrunner breaks with common stereotypes about old age, but also familiarises viewers with the inevitable ageing process. The protagonists of the Green Glove Gang prove that old age does not have to be a passive period; it can also be a time for discovering and developing new passions — which one is often not able to pursue due to the lack of time inherent to being professionally active.
Kim jest czarna profesjonalistka? Wizerunki Afroamerykanek w serialach Shondaland jako projekt społeczny
Authors: Gierszewska Karolina
Published: December 2023

Contemporary popular culture is increasingly steeped in social commentary, and is more and more frequently used as a platform to engage with politically relevant themes. In this article, I deconstruct the Black professional, a character trope that features prominently in TV shows produced by Shonda Rhimes. My analysis is focused on the protagonists of Grey’s Anatomy and How to Get Away with Murder. While its theoretical framework is derived from certain considerations originating from the Black Arts Movement and intersectional feminist theory as introduced by bell hooks, I also view the discourse of the works discussed through the lens of African American history.
Wiedza kulturowa i wiedza kulturoznawcza. Zarys problematyki
Authors: Majewski Tomasz
Published: December 2023

Wiedza kulturowa to wiedza umiejscowiona, to rozumienie „od wewnątrz” wartości, zwyczajów, zasad i praktyk, które są wspólne dla danego społeczeństwa lub grupy. W jej ramach istnieją wspólne, podzielane przez wszystkich reguły interpretacyjne, konstrukcje rzeczywistości i światopoglądy. Wiedza kulturowa jest ściśle powiązana z wiedzą ukrytą, której nie da się w pełni wyartykułować ani wyjaśnić, w przeciwieństwie do wiedzy jawnej. W odwrotnym kierunku wydaje się zmierzać teoria kulturowa i wiedza propozycjonalna na temat kultury, które pozorują uniwersalne „spojrzenie znikąd”. Autor artykułu zastanawia się nad relacją typów idealnych „wiedzy kulturowej” i „wiedzy kulturoznawczej” w ramach projektowanej „ekologii form wiedzy”. Pyta, jak ta relacja była modelowana u początków instytucjonalizacji kulturoznawstwa jako dyscypliny naukowej w latach siedemdziesiątych ubiegłego wieku. Wymiar poznawczy spotyka się tutaj z wymiarem praktycznym. Rodzi się zatem pytanie, czy możliwe jest takie modelowanie tej relacji, aby kulturoznawstwo odnalazło się współcześnie w roli dyscypliny badawczej oferującej wglądy we własną „partykularną wiedzę kulturową” jako wiedzę poznawczo wartościową i jako dyskurs terapeutyczny dla patologii, dysfunkcji i nadużyć ideologicznych związanych z „kulturowym światem pojęć własnych”.
Kelta temetkezések embertani vizsgálata Vác-Kavicsbánya lelőhelyről
Authors: Köhler Kitti
Published: December 2023

In this paper the results of the physical anthropological analysis of 18 (12 inhumated, 6 cremated) Celtic graves – excavated from the site of Vác-Kavicsbánya – are presented. Among them 8 males, 7 females and 4 individuals of indeterminable sex (one of them is a child) could be distinguished. Due to the low number of the examinable graves the detailed paleodemographic analysis couldn’t be compiled. The morphometric analysis could be performed only in the case of 2 females, who showed the presence of the brachycranic individuals in the series. This anthropological component can be linked to the immigrant Celts. The pathological investigation based on macromorphological investigation, showed the occurrence of common diseases, which were characteristic in the prehistoric times (like poroticus hyperostosis or fracture). The examination of cremated graves showed that the amount/weight of the ashes was low, which could be caused by several factors (for example by selective collection of ashes from the pyre). Beside it, the colour of the ashes was mainly yellowish white, which suggests that the cremation proses were at a low temperature.
14–21 éves sportolók klasszikus antropometriai és modern műszeres technikákkal becsült testzsírszázalékának összehasonlító elemzése
Authors: Rátz-Sulyok Fanny Zselyke , Jang-Kapuy Csilla , Bakonyi Péter , Petridis Leonidas , Zsákai Annamária , Szabó Tamás
Published: December 2023

Currently, one of the most accurate measurements of body composition components, including the fat content of the body is based on the method of dual X-ray absorptiometry (DEXA). The application of the DEXA method in clinical setting is usually limited to the assessment of bone health status due to the device’s cost and immobile nature, therefore in sport diagnostics the body composition estimation is usually carried out with other methods, such as bioimpedance analysis or anthropometrical methods based on the measurement of body dimensions, which ensure a rapid, accurate and frequently repeatable way of examination. For our research goal we choose the comparison of the most frequently used body fat percentage estimation methods. The accuracy of the other methods in the light of the DEXA estimations is presented. Sport Sciences and Diagnostic Research Centre of the Hungarian Handball Federation coordinated the assessment of 171 young elite handball players (14–21-year-olds), whose body composition estimations were performed in the spring and summer of 2023. The preliminary analysis of body fat percentage estimates in handball players carried out with different methods showed that the rapid and cost-efficient estimations based on anthropometric skinfold measurements can substitute the body fat percentage estimation method based on the clinically acclaimed golden standard dual X-ray absorptiometry technology. Body fat percentage estimation via InBody 770 device showed significantly lower values compared to the DEXA method, however this difference was consistent, therefore body composition assessment via InBody device can serve as an alternative of monitoring personal progress and status. We also carried out examinations with a novel ultrasound technology aided by BodyMetrix device, its subcutaneous fat thickness measurement estimated accurately the skinfold thicknesses on human body, its body fat percentage estimation based the skinfold thicknesses was adequately accurate compared to the DEXA method. With the aid of available DEXA measurement results and with the aim of creating an alternative method with low instrument requirement for body fat percentage estimation, which can be used with the highest accuracy particularly considering the body composition of young elite athletes, we created a modified sport-specific body fat percentage estimation equation. Our new estimation method was based on classical anthropometric skinfold measurements, and it accurately correlated with the DEXA body fat% estimates in case of young elite handball players.
Campanhismo, modelo e função social: o caso da Campanha de Aperfeiçoamento e Difusão do Ensino Secundário CADES (1953-1969)
Authors: Oliveira George Fredman Santos , Vaz Alexandre Fernandez
Published: December 2023

O texto do artigo a seguir reflete sobre o fenômeno do campanhismo no Brasil, empregando como paradigma do campo educacional a Campanha de Aperfeiçoamento e Difusão do Ensino Secundário (CADES) entre os anos de 1953-1969, resultado da pesquisa a respeito do tema, utiliza-se da análise de fontes documentais dessa campanha, textos historiográficos, sociológicos e dados do IBGE. O presente texto examina o modelo e a função das campanhas num mapa cognitivo característico do período da Guerra Fria, do desenvolvimentismo e do governo militarizado desde o golpe de 1964 na formação de professores para o ensino secundário no Brasil. Aponta igualmente que o modelo do campanhismo se adapta ao mapa cognitivo de forma a ser uma expressão do tempo, e a CADES como uma materialização de uma política pública para a formação emergencial de professores do ensino secundário de forma exemplar dentro do modelo.
ACCOUNTING AND ANALYTICAL SUPPORT FOR MAKING FINANCIAL DECISIONS IN THE SOLVENCY MANAGEMENT OF THE ENTERPRISE
Authors: Iershovа Natalia , Grinko Alla
Published: December 2023

The article is devoted to the study of accounting and analytical support for financial decision-making in managing the solvency of the enterprise. It is substantiated that solvency is an important factor in the formation of the company's financial management policy and strategy. The importance of accounting and analytical information for management needs is outlined, the solvency of Ukrainian enterprises is assessed based on statistical data, "bottlenecks" in the formation of information flows in the process of managing the solvency of the enterprise are identified. The information and analytical function of accounting contributes to the adoption of financial decisions when managing the company's solvency. New approaches are relevant for predicting the further financial development of an enterprise and assessing risks that can reduce the solvency of an enterprise. The tasks of the accounting system for information support of participants in the process of making financial decisions are considered. A model of accounting support for making financial decisions is proposed, which will improve the management of the enterprise's solvency. Attention is paid to the role and importance of management accounting in the formation of information for management. The results of the study have a practical focus, since a well-constructed model of accounting and analytical support for financial decision-making makes it possible to achieve business development stability.
MANAGEMENT OF THE FINANCIAL SECURITY OF THE ENTERPRISE IN MODERN CONDITIONS
Authors: Volosnikova Nataliia , Reshetniak Natalia , Abramov Fedir
Published: December 2023

The article examines the concept of financial support as a set of necessary resources and sources of their formation for the effective functioning of the enterprise. It is noted that significant difficulties in the formation and adoption of the current production plan arise with limited resources. The essence of the financial support structure is determined, the main principles on which the financial support mechanism is based and the importance of financial support both at the operational and strategic level of enterprise management are characterized. The analysis was carried out and directions for improvement of resource provision at the enterprise were considered. The resource limitations of an industrial enterprise during the formation of a plan include limitations on the provision of material, labor, financial and informational resources. The principle of calculating the need for the specified types of resources using the economic-mathematical model of the cumulative production technology of the industrial enterprise is proposed. It is substantiated that the synergistic effect of the corporate security system depends on such factors as the resource provision of the enterprise, the consistency of the direction of movement of the vectors of subsystems of economic, technological, informational, legal, financial, personnel, transactional, logistical and resource security with the goals of the general strategy of corporate security, construction features dynamic system of corporate security; influential changes in the micro- and macroeconomic environment, reliability of the general system of corporate security, stability and efficiency of the management system of the system of corporate security; characteristics of the corporate security system. It was concluded that the basis of the synergistic effect of the corporate security system is the optimal combination of individual elements of the system, the effectiveness of their interaction and quality. A model of the organizational and economic interaction of the processes of using structural components of financial support for enterprise activity is proposed, and an algorithm for the formation of resource support for enterprise activity in modern conditions is presented.
In situ FRET measurement of cellular tension using conventional confocal laser microscopy in newly established reporter mice expressing actinin tension sensor
Authors: Wang Junfeng , Maeda Eijiro , Tsujimura Yuki , Abe Takaya , Kiyonari Hiroshi , Kitaguchi Tetsuya , Yokota Hideo , Matsumoto Takeo
Published: December 2023

FRET-based sensors are utilized for real-time measurements of cellular tension. However, transfection of the sensor gene shows low efficacy and is only effective for a short period. Reporter mice expressing such sensors have been developed, but sensor fluorescence has not been measured successfully using conventional confocal microscopy. Therefore, methods for spatiotemporal measurement of cellular tension in vivo or ex vivo are still limited. We established a reporter mouse line expressing FRET-based actinin tension sensors consisting of EGFP as the donor and mCherry as the acceptor and whose FRET ratio change is observable with confocal microscopy. Tension-induced changes in FRET signals were monitored in the aorta and tail tendon fascicles, as well as aortic smooth muscle cells isolated from these mice. The pattern of FRET changes was distinctive, depending on tissue type. Indeed, aortic smooth muscle cells exhibit different sensitivity to macroscopic tensile strain in situand in an isolated state. This mouse strain will enable novel types of biomechanical investigations of cell functions in important physiological events.
Illuminating T cell-dendritic cell interactions in vivo by FlAsHing antigens
Authors: Akkaya Munir , Souz Jafar Al , Williams Daniel , Kamdar Rahul , Kamenyeva Olena , Kabat Juraj , Shevach Ethan M. , Akkaya Billur
Published: December 2023

Delineating the complex network of interactions between antigen-specific T cells and antigen presenting cells (APCs) is crucial for effective precision therapies against cancer, chronic infections, and autoimmunity. However, the existing arsenal for examining antigen-specific T cell interactions is restricted to a select few antigen-T cell receptor pairs, with limited in situ utility. This lack of versatility is largely due to the disruptive effects of reagents on the immune synapse, which hinder real-time monitoring of antigen-specific interactions. To address this limitation, we have developed a novel and versatile immune monitoring strategy by adding a short cysteine-rich tag to antigenic peptides that emits fluorescence upon binding to thiol-reactive biarsenical hairpin compounds. Our findings demonstrate the specificity and durability of the novel antigen-targeting probes during dynamic immune monitoring in vitro and in vivo. This strategy opens new avenues for biological validation of T-cell receptors with newly identified epitopes by revealing the behavior of previously unrecognized antigen-receptor pairs, expanding our understanding of T cell responses.
Upstream rainout processes govern tree-ring oxygen isotopes with implications for monsoon and tropical hydroclimate reconstruction
Authors: Chen I-Ching , Hau Nguyen-Xuan , Sano Masaki , Nakatsuka Takeshi , Anchukaitis Kevin , Ngo-Duc Thanh , Chang Ying-Shuo , Chen Shin-Hao , Wang Szu-Hao , Wei Hsin-Lin , Li Zhen , Thuong Le-Thi , Minh Tran Binh
Published: December 2023

The interpretation of oxygen isotope ratios (δ18O) in proxy records over the Asian monsoon region remains a significant debate, particularly regarding the importance of the local "amount effect" versus upstream rainout processes. Here, we present a precisely dated annual-resolution network of tree-ring oxygen isotopes (δ18Otr) encompassing various tree species and local climates. We demonstrate that δ18Otr is a reliable proxy for δ18O in precipitation (δ18Opr) and that upstream rainout processes, rather than the local amount effect, predominantly govern the δ18Otr variations. The El Niño-Southern Oscillation and the associated Walker Circulation play a crucial role in modulating upstream atmospheric convective activity, which in turn influences δ18Otr. By elucidating the spatial coherence between climate observations and δ18Opr proxies, our research marks a pivotal advancement in δ18Otr network development, which is set to advance the interpretation of monsoon dynamics and the reconstruction of tropical hydroclimates.
Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS
Authors: Pottinger Tess D. , Motelow Joshua E. , Povysil Gundula , Moreno Cristiane A. Martins , Ren Zhong , Phatnani Hemali , Aitman Timothy J. , Santoyo-Lopez Javier , Mitsumoto Hiroshi , Goldstein David B. , Harms Matthew B.
Published: December 2023

Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting over 30,000 people in the United States. It is characterized by the progressive decline of the nervous system that leads to the weakening of muscles which impacts physical function. Approximately, 15% of individuals diagnosed with ALS have a known genetic variant that contributes to their disease. As therapies that slow or prevent symptoms, such as antisense oligonucleotides, continue to develop, it is important to discover novel genes that could be targets for treatment. Additionally, as cohorts continue to grow, performing analyses in ALS subtypes, such as primary lateral sclerosis (PLS), becomes possible due to an increase in power. These analyses could highlight novel pathways in disease manifestation.
Methods: Building on our previous discoveries using rare variant association analyses, we conducted rare variant burden testing on a substantially larger cohort of 6,970 ALS patients from a large multi-ethnic cohort as well as 166 PLS patients, and 22,524 controls. We used intolerant domain percentiles based on sub-region Residual Variation Intolerance Score (subRVIS) that have been described previously in conjunction with gene based collapsing approaches to conduct burden testing to identify genes that associate with ALS and PLS.
Results: A gene based collapsing model showed significant associations with SOD1, TARDBP, and TBK1 (OR=19.18, p = 3.67 × 10-39; OR=4.73, p = 2 × 10-10; OR=2.3, p = 7.49 × 10-9, respectively). These genes have been previously associated with ALS. Additionally, a significant novel control enriched gene, ALKBH3 (p = 4.88 × 10-7), was protective for ALS in this model. An intolerant domain based collapsing model showed a significant improvement in identifying regions in TARDBP that associated with ALS (OR=10.08, p = 3.62 × 10-16). Our PLS protein truncating variant collapsing analysis demonstrated significant case enrichment in ANTXR2 (p=8.38 x 10-6).
Conclusions: In a large multi-ethnic cohort of 6,970 ALS patients, rare variant burden testing validated known ALS genes and identified a novel potentially protective gene, ALKBH3. A first-ever analysis in 166 patients with PLS found a candidate association with loss-of-function mutations in ANTXR2.
Nearest Advocate: A Novel Event-based Time Delay Estimation Algorithm for Multi-Sensor Time-Series Data Synchronization
Authors: Schranz Christoph , Mayr Sebastian , Bernhart Severin , Halmich Christina
Published: December 2023

Estimating time delays in event-based time-series is a crucial task in signal processing as it affects the data quality and is a prerequisite for many subsequent analyses. In particular, data acquired from wearable devices often suffer from a low timestamp precision or clock drift. Current state-of-the-art methods such as Pearson Cross-Correlation are sensitive to typical data quality issues, e.g. misdetected events, and Dynamic Time Warping is computationally expensive. To overcome these limitations, we propose Nearest Advocate, a novel event-based time delay estimation method for multi-sensor time-series data synchronisation. We evaluate its performance using three independent datasets acquired from wearable sensor systems, demonstrating its superior precision, particularly for short, noisy time-series with missing events. Additionally, we introduce a sparse variant that balances precision and runtime. Finally, we demonstrate how Nearest Advocate can be used to solve the problem of linear as well as non-linear clock drifts. Thus, Nearest Advocate offers a promising opportunity for time delay estimation and post-hoc synchronization for challenging datasets across various applications.
Advancing Infrastructure Resilience: Machine Learning-Based Prediction of Bridges’ Rating Factors under Autonomous Truck Platoons
Authors: Elshazli Mohamed , Hussein Dina , Bhat Ganapati , Abdel-Rahim Ahmed , Ibrahim Ahmed
Published: December 2023

The operational characteristics of freight shipment will significantly change after the imple- mentation of Autonomous and Connected Trucks (ACT). This change will have a significant impact on freight mobility, transportation safety, and the sustainability of infrastructure. Truck platooning is an emerging truck configuration that is expected to become operational in the future due to the rapid advancements in connected vehicle technology and autonomous driving assistance. The platooning configuration enables trucks to be connected with them- selves and the surrounding infrastructure. This arrangement has shown to be a promising solution to improve the vehicles’ fuel efficiency, reduce carbon dioxide emission, reduce traf- fic congestion, and improve transportation service. However, platooning may accelerate the damage accumulation of pavement and bridge structures due to the formation of multiple load axles within each platoon since those structures were not designed for such loads. Ac- cording to AASHTO, bridges are designed based on a notional live load model comprised of one or two trucks per lane in conjunction with or separate from an applied uniform load (AASHTO, LRFD 2022). This damage, if accumulated, its repair would require billions of dollars from the government and would impede the movement of both people and goods. The potential damage to infrastructure may arise due to various factors such as the number of trucks in a platoon, gap spacing between trucks, and the type of trucks. This research work includes a thorough parametric study with 295,200 computer simulations using SAP 2000.
The goal was to evaluate the effect of different truck platooning configurations on the load rating of existing bridges. The obtained results served as the dataset for training various machine learning models, including Random Tree, Random Forest, Multi-Layer Perceptron (MLP), Support Vector Regression (SVR), K-Nearest Neighbor (KNN), and Extreme Gra- dient Boosting (XGBoost). Results showed that Random Forest model performed the best, with the lowest prediction errors. The proposed machine learning model has shown its ef- fectiveness in identifying optimal platooning configurations for bridge structures within the scope of the study.
Effects of adjuvants on the effectiveness and rainfastness of rimsulfuron in potato (Solanum tuberosum L.)
Authors: Alebrahim Mohammad Taghi , Kalkhoran Elham Samadi , Khatami Seyedeh Asieh
Published: December 2023

The use of adjuvants is an effective way to improve weed control. We evaluated the effect of a non-ionic surfactant (NIS, Contact) and a crop oil concentrate (COC, Renol) on the efficacy and rainfastness of the rimsulfuron on redroot pigweed (Amaranthus retroflexus L.) and common lambsquarters (Chenopodium album L.) in pot studies as well as NIS surfactant in a potato under field conditions. In outdoor pot studies, NIS (0.15 L ha− 1) and COC (0.5 L ha− 1) did not improve the efficacy of rimsulfuron on A. retroflexus while they enhanced the performance and rainfastness of rimsulfuron 14 and two-fold on Chenopodium album at those rates, respectively. However, increasing the NIS concentration to 1 L ha− 1 increased rimsulfuron efficacy by 11-fold for A. retroflexus compared to around 3-fold for C. album. The same treatment also reduced the rainfastness of rimsulfuron on A. retroflexus while improving the rainfastness of rimsulfuron on Chenopodium album compared to 0.04 L ha− 1. The ED50 and ED90 values indicated that the addition of the 0.2 L ha− 1 of NIS improved the efficacy of both recommended (60 g ai. ha− 1) and the reduced (30 g ai. ha− 1) doses of rimsulfuron in field conditions. The highest potato yield (60 t ha− 1) was recorded when rimsulfuron was applied at recommended dose at three different crop growth stages including the development of leaves (S1), harvestable vegetative plants (S4), and tubers (S7), without using a NIS. Overall, the NIS improved rimsulfuron efficacy, especially when the herbicide was applied at a lower dose.
Detection of Bluetongue Virus Antibodies and Associated Risk Factors among Camels (Camelus dromedarius) in Central Sudan: A Cross-Sectional Study
Authors: Saeed Shamsaldeen , Elhag Ahmed E. , Adam Ibrahim A. , Ibrahim Abdul Naeem , Hassan Nosiaba F. , Adekola Adewole A. , Goni Mohammed D. , Yazici Zafer , Abdelaziz Sanaa A. , Aradaib Imadeldin E.
Published: December 2023

Bluetongue (BT) is a non-contagous arthorpbpd-born viral infection transmitted by insects, particularly biting midges of the Culicoides species, and can affect wild and domestic ruminants, including sheep, goats,cattels, deer, elk, and camales. This study aims to determine the prevalence of BTV antibodies in camels reared in central Sudan and the potential risk factors contributing to its epidemiology. A total of 184 blood samples were collected between November 2014 and May 2015 from six localities in Khartoum state in Sudan using multi-stage random sampling. The sampled farms' characteristics and management factors were obtained using a semi-structured questionnaire. Serology for BTV antibody detection was performed using a competitive enzyme-linked immunosorbent assay (cELISA). Our findings indicated a high prevalence of circulating BTV. antibodies in camels' sera (66.8%, 95% CI = 0.6–0.73). Camels raised on farms were more likely to contract the disease (OR = 0.424, CI = 0.223–1.071, p-value = 0.040) than camels bought from the market or other farms. The presence of other animals in the camels' herds, such as sheep, goats, and cattle, has increased the risk of infection with diseases compared to camels that are reared alone in the farms (OR = 0.176, CI = 0.43–0.771, p-value = 0.016). The high BTV seroprevalence indicates the endemicity of BTV, the risk of previous exposure, and the potentiality for BTV Transmission among asymptomatic camels. Control measurements, including vector control, trade restriction, and vaccination, are recommended to protect vulnerable animal species from BTV infection.
A Novel Approach to Nursing Clinical Intelligent Decision-Making: Integration of Large Language Models and Local Knowledge Bases
Authors: Xiong Liping , Zeng Qiqiao , Deng Wuhong , Luo Weixiang , Liu Ronghui
Published: December 2023

Objective: The purpose of this study is to develop a novel method for nursing clinical intelligent decision-making that integrates Large Language Models (LLMs) with local knowledge bases, aiming to enhance the accuracy and reliability of clinical decisions in nursing.
Methods: Initially, we established a multi-level classified nursing knowledge base by collecting textual knowledge from public knowledge platforms and integrating selected contents from peer-reviewed nursing journals, academic papers, textbooks, and nursing standards. Subsequently, data knowledge was collected from clinical records and normalized to form a data knowledge base. Additionally, we proposed a nursing clinical decision-making system paradigm based on prompt learning in “LLMs + professional knowledge bases”, addressing the issue of catastrophic forgetting common in domain-specific question-answering systems due to the “data + fine-tuning” paradigm.
Results: Utilizing the aforementioned methodology, we successfully constructed a nursing knowledge base and developed a decision-making system. The evaluation results demonstrate that this system possesses high accuracy, logical coherence, completeness, and readability in clinical nursing decisions. It enhances the convenience and efficiency of medical staff in clinical decision-making and effectively improves the applicability of LLMs in the field of nursing.
Conclusion: This study validates the effectiveness of the approach that combines LLMs with local knowledge bases in nursing clinical decision-making. This method not only enhances the accuracy of decisions but also provides efficient decision support in resource-limited scenarios. In the future, this approach is expected to be applied in a broader range of nursing settings, offering new perspectives and tools for clinical nursing practice and research.
Optimal design of non-uniform curved grid-stiffened shell with different stiffener patterns
Authors: Yu Sun , Xiaoang Li , Yan Zhou , Zhou Zitong , Wang Bo , Tian Kuo
Published: December 2023

This paper presents a non-uniform curved grid-stiffened shell design method aiming to enhance structural performance using various stiffener patterns, allowing simultaneous optimization of stiffener thickness and stiffener layout. Firstly, the grid-stiffened cell description function is defined using quadratic polynomial functions, comprising the orthogrid, the triangle grid, the rotated triangle grid and the Kagome grid. Then, the non-uniform stiffener layout description function is established using the sawtooth function, while a filter function is employed to ensure the smooth and continuous of the stiffeners. Moreover, the analytical sensitivity is thoroughly derived, and the optimization problem is formulated. Finally, the effectiveness of the proposed method is demonstrated through three representative numerical examples: the cantilever beam, the special-shaped plate and the S-shape shell. The study concludes that the proposed method can optimize arbitrary flat plates by embedding the design domain into the background grid. Additionally, the proposed method can be extended to perform stiffener design on complex surfaces using mesh projection technology. Optimization results indicate that the non-uniform curved grid-stiffened shell design exhibits superior structural performance compared to the uniform grid-stiffened shell design.
Effects of green tea consumption on oxidative stress and DNA repair in hospital staff exposed to low dose ionizing radiation
Authors: Wang Ping , Huo Yuan , gao xue , Chen Jiarui , Zhang Zengli
Published: December 2023

Ionizing radiation (IR) is known to induce the formation of reactive oxygen species, which are linked to chronic diseases. Tea is the most commonly consumed beverage worldwide. Tea consumption was demonstrated to have ameliorative effects in subjects with chronic diseases, which were explained by antioxidant and anti-inflammatory effects. This cross-sectional study to evaluate the potential benefits of green tea consumption on oxidative stress and DNA repair induced by occupational exposure to IR. A cohort of hospital workers exposed to occupational levels of IR were divided into two groups based on their tea consumption. Peripheral blood cell count were counted by a automated Coulter Counter. Markers of oxidative stress and inflammatory were detected commercial kit. DNA repair gene expression was detected by RT-PCR.The subjects in the no tea-consuming group presented with significantly decreased plasma levels of total antioxidant content (TAC) and superoxide dismutase (SOD) compared to the tea drinking group. In contrast, the non-tea-drinking group showed significantly increased plasma levels of malondialdehyde (MDA) and 8-hydroxy-2 deoxyguanosine (8-OHdG), indicating oxidative stress at the tissue and DNA levels, respectively. The Tea Group subjects showed significantly lower plasma levels of C-reactive protein and TNF-α compared with the No Tea Group. However, the expressions of DNA repair genes (OGG1 and XRCC1) were not significantly different between two groups. In conclusion, green tea consumption might be a novel method for decreasing levels of oxidative stress in workers exposed to low levels of IR.
Lyapunov exponents and shear-related chaos for a Hopf bifurcation with additive noise
Authors: Baxendale Peter
Published: December 2023

This paper considers the effect of additive white noise on the normal form for the supercritical Hopf bifurcation in 2 dimensions. The main results involve the asymptotic behavior of the top Lyapunov exponent λ associated with this random dynamical system as one or more of the parameters in the system tend to 0 or ∞. This enables the construction of a bifurcation diagram in parameter space showing stable regions where λ <0 (implying synchronization) and unstable regions where λ > 0 (implying chaotic behavior). The value of λ depends strongly on the shearing effect of the twist factor b/a of the deterministic Hopf bifurcation. If b/a is sufficiently small then λ <0$ regardless of all the other parameters in the system. But when all the parameters except b are fixed then λ grows like a positive multiple of b2/3 as b → ∞.
2020 Mathematics Subject Classification: 37H10, 37H15, 60H10, 60J60.
Comparative analysis of the chimpanzee and human brain superficial structural connectivities
Authors: Chauvel Maëlig , Pascucci Marco , Uszynski Ivy , Herlin Bastien , Mangin Jean-François , Hopkins William , Poupon Cyril
Published: December 2023

Diffusion MRI tractography (dMRI) has fundamentally transformed our ability to investigate white matter pathways in the human brain. While long-range connections have been extensively studied, short-range white matter bundles (SWMBs) have remained a relatively underexplored aspect of brain connectivity. This study undertakes a comprehensive examination of SWMB connectivity in both the human and chimpanzee brains, employing a novel combination of empirical and geometric methodologies to classify SWMB morphology in an objective manner. Leveraging two anatomical atlases, the Ginkgo Chauvel chimpanzee atlas and the Ginkgo Chauvel human atlas, comprising respectively 844 and 1375 superficial bundles, this research focuses on sparse representations of the morphology of SWMBs to explore the little-understood superficial connectivity of the chimpanzee brain and facilitate a deeper understanding of the variability in shape of these bundles. Ultimately, the analysis aims to uncover both commonalities and disparities in SWMBs between chimpanzees and humans, shedding light on the evolution and organization of these crucial neural structures.
RETRACTED: Assessing Heat Stress Tolerance and Physiological Adaptations in Wheat Varieties: A Comprehensive Study on Phenotypic Parameters and Physiological Responses
Authors: Shrestha Samir , Magar Sunita Thapa , Yadav Pankaj Kumar
Published: December 2023

The authors have requested that this preprint be removed from Research Square.
Population Structure Analysis and Marker Trait Association in Traditional Rice (Oryza sativa L.) Landraces of Kerala under High Temperature Condition
Authors: S Sowmiya , R. Beena , N Nithya , N Manikanta Ch L
Published: December 2023

Rice productivity is significantly impacted by a significant abiotic stress called heat stress. To adapt to current or future heat stress, it is necessary to understand the physiological basis of heat tolerance. Thus, the purpose of this study was to assess the physiological, morphological, and yield parameters of fifty traditional rice landraces when subjected to high temperature stress, as well as to identify SSR (Simple Sequence Repeat) markers associated with these traits. The experiment was designed in a completely randomised manner, with two treatment levels, control and high temperature stress (36 ± 2oC), each with three replications. Thirty SSR primers were used to analyze genetic diversity and population structure among 50 traditional rice landraces collected from Regional Agricultural Research Station, Pattambi, Kerala. The fifty traditional rice landraces were clustered using the average linkage method to determine their relationship to one another. The accessions were all grouped primarily into three clusters. According to principal component analysis, under high temperature conditions, the first principal component accounted for 24.602 percent of the variation, while the second component accounted for 20.587 percent of the variation. The accessions were clearly divided into three subpopulations based on population structure analysis. Under high temperature and control conditions, GLM (Generalized Linear Model) analysis revealed highly significant marker trait associations.RM5715, RM10793, and RM471 were among those that showed associations with multiple traits. Molecular markers and identified tolerant accessions can be used in breeding programmes to create high-yielding, temperature-tolerant rice landraces.
‹Double bind›-Phänomene in der Fortbildung von Lehrkräften an beruflichen Schulen im Kontext der Digitalisierung
Authors: Weber Susanne , Zarnow Stefanie , Hackenberg Tobias , Hiller Frank , Seeber Susan , Geiser Patrick , Schumann Matthias , Busse Julian , Achtenhagen Frank
Published: December 2023

Digitalisierung stellt Lehrkräfte beruflicher Schulen vor vielfältige neue Herausforderungen. Zum Erhalt ihrer Professionalisierung müssen sie sich laufend fortbilden, wollen sie die Qualität des Unterrichts sicherstellen. Studien zeigen, dass die Erfolgserwartungen an Fortbildungen (FB) von Lehrkräften insbesondere im Hinblick auf das Potenzial digitaler Medien noch nicht voll ausgeschöpft sind. Dies scheint mit vielfältigen administrativen und gesetzlichen Vorgaben, mit dem Wirken unterschiedlicher Akteure sowie funktionalen Zuständigkeiten zu korrespondieren. Somit ist die Professionalisierung der Lehrkräfte nicht nur von ihren individuellen Entscheidungen, sondern auch von denen anderer Akteure und den dabei auftretenden Interaktionen abhängig. Dabei kommt es nicht selten zu Spannungen auch in der Form von ‹Double Bind›-Phänomenen, die sich nur in einem grösseren Systemkontext identifizieren, verbalisieren, interpretieren, aufbrechen und lösen lassen. In dieser Studie zeichnen wir die Struktur und Interaktionen der Akteure der FB für Lehrkräfte an beruflichen Schulen mittels der Kulturhistorischen Tätigkeitstheorie sowie aktueller Forschungsergebnisse nach, verorten darin die in einer Interviewstudie mit 46 Lehrkräften wahrgenommenen Interaktionen und analysieren diese im Hinblick auf ‹Double Bind›-Phänomene. Die Ergebnisse zeigen, dass Lehrkräfte im Rahmen ihrer FB mit kritischen Entscheidungen i. S. v. ‹Double Binds› konfrontiert sind, sowohl auf struktureller Ebene als auch im Hinblick auf ihr Professionsverständnis wie auch auf einstellungs- und interessensbezogene Aspekte.
Manteltext: Grundzüge einer medienpädagogischen Organisationsforschung
Authors: Helbig Christian
Published: December 2023

Die kumulative Dissertation hat das Ziel, Verbindungen zwischen Organisationskonzepten und Medienpädagogik zu entwickeln sowie die Bedeutung und Forschungsperspektiven einer daraus resultierenden medienpädagogischen Organisationsforschung empirisch zu untersuchen. Die Forschungsfrage der Arbeit lautet: «Welchen Forschungsperspektiven bietet eine medienpädagogische Organisationsforschung?». Zur Bearbeitung der Zielstellung und der Forschungsfrage werden drei Teilfragen gestellt, die im Zusammenspiel von fünf Einzelpublikationen und in diesem Manteltext beantwortet werden:1. Welche Bedeutung nehmen Organisationskonzepte in den Begründungszusammenhängen der Medienpädagogik ein?2. Wie können Organisationskonzepte theoretisch an medienpädagogische ­Forschung anschliessen?3. Welchen empirischen Erkenntnisgewinn leistet eine praxeologisch verortete medienpädagogische Organisationsforschung?Entsprechend der Teilfragen ist die Arbeit in drei Kapitel sowie einer Einleitung und einem Fazit gegliedert. Kapitel 2 betrachtet medienpädagogische Begründungszusammenhänge, ordnet diese in poststrukturalistische und normativitätskritische Positionen ein und sucht nach eingelagerten Hinweisen auf die Bedeutung von Organisationen. Kapitel 3 stellt theoretische Verbindungen zwischen medienpädagogischer Forschung und Organisationskonzepten her, die sowohl anhand sozialwissenschaftlicher als auch erziehungswissenschaftlicher Diskurse begründet werden. In Kapitel 4 wird eine praxeologische Position innerhalb einer medienpädagogischen Organisationsforschung eingenommen und die Dokumentarischen Methode bzw. die Dokumentarische Organisationsforschung als Forschungszugang begründet. Anschliessend wird eine qualitativ-empirische Studie, die anknüpfend an den methodologischen Rahmen konzipiert und durchgeführt wurde, beschrieben und in Bezug zum Gegenstand der Arbeit gesetzt. Die Ergebnisse zeigen erstens, dass Organisationen in den Begründungszusammenhängen der Medienpädagogik ein Desiderat darstellen und wenig theoretische oder empirische Anschlüsse existieren. Zweitens ist mit Bezug zur Human-Relations-Bewegung und der Strukturationstheorie medienpädagogisches Handeln als strukturiertes und strukturierendes Handeln in pädagogischen Organisationen zu beschreiben. Drittens fokussiert eine praxeologisch verortete medienpädagogische Organisationsforschung medienpädagogische Praktiken in Organisationen und deren Beziehung zu formalen Regeln und Strukturen. Die Ergebnisse der qualitativen Studie zeigen, dass medienpädagogisches Handeln als milieuspezifische Alltagspraktiken in Organisationen zu verstehen sind, die durch fachliche Qualifikationen, formale Regeln und Umweltbedingungen beeinflusst sind. Zusammenfassend zeigt die Dissertation neue Forschungsperspektiven auf, die eine medienpädagogische Organisationsforschung bieten kann und begründet damit ein weiteres Forschungsfeld medienpädagogischer Forschung.
THE NETWORKING OF RECRUITERS OF CHILD LABOUR IN SOME SELECTED BORDER COMMUNITIES IN SOUTH-WESTERN NIGERIA: A REVIEW OF THE LITERATURE
Authors:   Department of Sociology, Faculty of Social SciencesLagos State University, Ojo, Nigeria., Peter Sunday Adeniran , Samuel Oluranti ,   Department of Sociology, Faculty of Social SciencesLagos State University, Ojo, Nigeria., Jawando Jubril ,   Department of Sociology, Faculty of Social SciencesLagos State University, Ojo, Nigeria.
Published: December 2023

Child labourers constitute a growing proportion globally, as more children engage in it, in a bid to meet up with the financial situation for themselves or family support. Poverty, networking of recruiters and other circumstances could be responsible for this. This paper reviewed studies that have examined the networking that exists between recruiters of child labour and parents of child labourers. The Google Scholar search engine was used to search for published studies on the subject in the last ten years, between the 1st of January, 2011 and to 31st of December, 2021. A total of 40 studies were sampled, of which the majority based their conclusion using primary data and only two were retrospective studies, using secondary data. Only 30% of the studies were conducted in Nigeria, and 7% by social scientists with quantitative and triangulation methodologies with very few recruiters. Ninety percent (90%) of the studies reviewed, provided explanations why child labourers could fall into the hands of recruiters due to abject poverty, risk in child migration, lack of education, and cultural belief system. Others are, - the lack of jobs by the parents, parents low income, parents migration, myth of recruiters of child labourers. The study recommends the need for more sociological studies on the networking of the recruiters of child labour in border Communities, using only qualitative methodology to complement the existing literature on child labour.