bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Image Classification of Gastrointestinal Endoscopy Using Curriculum Self-Supervised Learning
Authors: Guo Han , Hosseini Ramtin , Somayajula Sai Ashish , Xie Pengtao
Published: June 2023

Endoscopy, a widely used medical procedure for examining the gastrointestinal (GI) tract to detect potential disorders, poses challenges in manual diagnosis due to non-specific symptoms and difficulties in accessing affected areas. While supervised machine learning models have proven effective in assisting clinical diagnosis of GI disorders, the scarcity of image-label pairs created by medical experts limits their availability. To address these limitations, we propose a curriculum self-supervised learning framework inspired by human curriculum learning. Our approach leverages the HyperKvasir dataset, which comprises 100k unlabeled GI images for pre-training and 10k labeled GI images for fine-tuning. By adopting our proposed method, we achieved an impressive top-1 accuracy of 88.92% and an F1 score of 73.39%. This represents a 2.1% increase over vanilla SimSiam for the top-1 accuracy and a 1.9% increase for the F1 score. The combination of self-supervised learning and a curriculum-based approach demonstrates the efficacy of our framework in advancing the diagnosis of GI disorders. Our study highlights the potential of curriculum self-supervised learning in utilizing unlabeled GI tract images to improve the diagnosis of GI disorders, paving the way for more accurate and efficient diagnosis in GI endoscopy.
Classification of rock facies using deep convolutional neural network
Authors: Soleimani Mohammad Hassan , Riahi Mohammad Ali , Bagheri Majid , Rahimi Mehran
Published: June 2023

Investigating rock facies is very important in the study of hydrocarbon reservoirs. The logs used in this research are related to facies logs from nine wells from the gas reservoir located in Kansas, USA. The rock facies identified in this study are based on a visual examination of a 4,149-foot core from 9 wells. The physical and chemical properties of stones were determined using special tools. The well-log includes five wireline logging curves (GR, resistivity log (RL), photoelectric effect (PE), difference neutron density porosity (DPHI) and average neutron density porosity (PHIA)) and two geological limiting variables (non-marine index - Nautical (NM_M) and relative position (RP)). Our goal in this paper is to develop an effective model based on deep learning for geological facies classification in wells. The classification of facies is done by studying the lithological characteristics of rocks, which are the characteristics of modern sediments accumulated in specific physical and geographical conditions. This study presents a new 1D-CNN model trained on different optimization algorithms. Using normal well-log data is one of the main advantages of the proposed model. The proposed model is compared with the support vector machine model and the nearest neighbor model and shows more accurate results compared to them. This model shows successful results in the study of well log data and therefore it can be suggested as a suitable and effective approach for processing well log data required for lithology.
Dynamic Analysis of Multi-Storey Building for Minimization of Lateral Displacement due to Earthquake using Shear Wall
Authors: Yadav Kushalkumar , Sharma R. L.
Published: June 2023

Shear walls are one of the most commonly used elements in Multi-Storeybuildings to resist the lateral loads due to earthquakes. In this paper, a multistorey building (with and without shear walls) is modeled and analyzed using STAAD-Pro. The prototype models are also tested on a shake table in the structural dynamics lab. The results of STAAD-Pro and Shake tables are compared. The main focus of the study is to investigate the seismic behavior of shear walls in multi-storey buildings and the applicabilty of the STAAD-Pro simulation to multi-storey buildings with shear walls. The modelling was done as per the Indian Standard Code IS 1893:2002, criteria for earthquake resistant design of structures part 1 general provisions and buildings. The materials used for modelling the building conforms to Indian Standard codes IS456:2000 and IS875:1987. The displacements and storey drifts computed using STAAD-Pro and shake table laboratory testing are compared. It has been found that there is complete agreement of the results. It is therefore concluded that the STAAD-Pro analysis can be used to analysed multi-stored buildings.
Exploring the Potential for Bamboo Agroforestry through Value Chain Approach in Thailand, using Cloud-based Data Management on Google Earth Engine
Authors: Amatyakul Wasita , Orozco Sebastian , Bunschoten Raoul
Published: June 2023

The global construction sector consumes almost half of the world's total material production footprint, implying it is the highest single-category material footprint across the global economy. In the search for nature-based alternatives, bamboo grass can become a mainstream building material in the global tropical belt due to significantly shorter rotation times compared to softwood or hardwood species. To determine bamboo potential within a value-chain work frame, the first step is to evaluate the potential land for cultivation. Technically driven soil selection, with optimal climatic conditions, can generate culms taller than 20 m or, on the contrary, culms of a maximum of 6 to 7 m in height. The correct choice of soil also favors the plantation owner since faster plant development will be observed; the plantation will show a higher number of culms, larger diameters, cheaper production, and shorter times until plant maturity, thus requiring less time to recover the initial investment. This research presents a remote-sensing-based tool for surveying and exploring bamboo agroforestry potential over the entire national territory of Thailand based on climatic conditions, altitude, topography, existing land cover, and soil characteristics (texture and acidity). Through the implementation of the research, a total amount of 345,838 km² with viable growth conditions was discovered. 45,968 km² (13.29%) show basic compatibility levels, 242,198 km² (70.03%) show intermediate levels and 57,672 km² (16.68%) present optimal growth conditions. The corresponding regions were located on an interactive geoportal with a 100 m-per-pixel resolution and the ability to benchmark the individual selection criteria.
Glycolysis rate-limiting enzyme PFKP: A pan-cancer predictor for prognostic significant, immunological correlation, and drug sensitivity prediction
Authors: Peng Jian , Li Pingping , Li Yuan , Quan Jichuan , Yao Yanwei , Duan Junfang , Liu Xuemei , Li Hao , Yuan Dajiang , Wang Xiaoru
Published: June 2023

Background
PFKP (phosphofructokinase, platelet), a rate-limiting enzyme of glycolysis, plays a decisive role in various human physio pathological processes. Multiple function of PFKP in different cancer types was reported, including lung cancer, breast cancer et al. However, systematic pan-cancer analysis of PFKP has not been performed now, which could reflect its clinically value about diagnosis, prognosis, drug sensitivity, and immunological correlation.
Methods
Systematic bioinformation analysis of PFKP was performed based on several public datasets including TCGA (The Cancer Genome Atlas), CCLE (Cancer Cell Line Encyclopedia), GTEx (Genotype-Tissue Expression Project), and HPA (Human Protein Atlas). Prospective carcinogenesis of PFKP in pan-cancer was estimated by expression analysis, effect on patients’ prognosis, diagnosis significant evaluation, and immunity regulation estimation. Then, pan-cancer function enrichment of PFKP was also accessed through its effect on signaling score and gene expression profile. Finally, upstream expressing regulation of PFKP was explored by promoter DNA methylation and transcription factors (TFs) prediction.
Results
Our analysis revealed that highly expression of PFKP was found in most cancer types. Meanwhile, high level of PFKP displayed a significant correlation with poor prognosis of patients across pan-cancer. And a fine diagnosis value of PFKP was summarized, especially in its positive correlation with PD-L1 (programmed cell death-Ligand 1). Then, we also found an obvious immunity regulating effect of PFKP in most cancer types. PFKP also had a remarkably negative correlation with several cancer drugs. Finally, ectopic expression of PFKP may depend on DNA methylation and several predicated transcription factors, including KLF (KLF transcription factor) and Sp (Sp transcription factor) family.
Conclusion
This pan-cancer analysis revealed that high expression level of PFKP might be a fine biomarker and predictor in most cancer types. Meanwhile, performance of PFKP across pan-cancer also implied its meaningful role in cancer immunity regulation even in immunotherapy and drug resistance. All in all, PFKP might be explored as an aux monitor for pan-cancer early prognosis and diagnosis.
Triple negative accessory breast cancer occurring concurrently with primary invasive breast carcinoma：a case report
Authors: Chen Ling , Wu Zujian , Guo Chi , Wan Hengjin , Wu Shouguo , Wang Guoping
Published: June 2023

Introduction Accessory breast cancer (ABC) is a very rare malignancy, and triple negative ABC with ipsilateral invasive in situ breast cancer is extremely infrequent. Binary breast tumors are controversial in terms of surgical methods and comprehensive treatment. Case presentation We share the case of a 64-year-old postmenopausal woman who was found to have an underarm mass for 3 months. Ultrasonography (US) and computed tomography (CT) suggested possible breast cancer with axillary lymph node metastasis. The patient underwent left modified radical mastectomy combined with axillary lymph node dissection. The postoperative pathology suggested a binary tumor, and we performed comprehensive treatment. Conclusion We share the treatment of a rare case of triple-negative para-breast cancer complicated with carcinoma in situ of the breast, hoping to have new therapeutic ideas for the treatment of this disease.
CBGA: A deep learning method for power grid communication networks service activity prediction
Authors: Liu Shangdong , Zhou Longfei , Shao Sisi , Zuo Jun , Ji Yimu
Published: June 2023

Power grid communication network service activity (PCNSA) refers to the active degree of access devices in the power grid communication networks that are actively providing services over a specific time period as a gauge of the operation status of power devices and load demand. Accurate monitoring of PCNSA helps optimize power dispatch, ensure supply and demand balance, and guide network planning and management. However, due to the complex nonlinear, multi-scale and multivariate characteristics of the PCNSA data, it is often difficult to capture its intrinsic patterns and dynamic changes through a simple model. To address this problem, this paper proposes a convolutional neural network(CNN), bi-directional gated recurrent unit(BiGRU), and attention mechanism(AM)-based service activity prediction method for power grid communication network, referred to as CBGA. CNN is used to extract the features of time-series data, BiGRU is used to capture the dependencies before and after the extracted data in both forward and backward directions and predict the service activity data of the next hour, and AM is used to capture the influence of feature states and enhance the extraction of important information. In this paper, experiments and comparisons are conducted on three real power grid communication network service datasets, and the experimental results demonstrate that the performance of this method is the best, with the smallest MAE and RMSE and the largest R2_score. In comparison to other models, CBGA model is better suited for the prediction of PCNSA and providing reliable data support for power communication network managers to make decisions .
A new valorization of faba bean waste: Fabrication of a low-cost adsorbent for efficient removal dyes from textile wastewater
Authors: Falil Fatima Zahra Fatima Zahra , ABOURRICHE Abdelrim , abouliatim younes , benhammou abdelaziz , Gourich Bouchaid , Allam Fouad
Published: June 2023

As part of the effort to extract more value from agri-food waste, innovative adsorbents have been prepared from faba bean waste (FB: Vicia Faba L) using a physical activation process at a moderate temperature of 350°C. This process, developed by the authors of the study, yields effective adsorbent materials known as HTFB. Due to the favorable physico-chemical properties of these materials, they are suitable for treating water that is contaminated with two different groups of dyes: anionic (orange G (OG)) and cationic dyes (crystal violet (CV) and methylene blue (MB)). The adsorption was carried out in batch mode to examine the influence of different operating conditions (pH, initial dye concentration, temperature, contact time, etc.) on the percentage of the removal dye. According to the experiment results, the materials developed have demonstrated a remarkable efficiency for the elimination of cationic dyes (66.86% for the crystal violet and 58.20% of the methylene blue) and a limited efficiency for anionic dyes (7.05% of the orange G) at natural pH. Kinetic studies showed that the pseudo-second-order model better described the adsorption of dyes onto the HTFB. Besides, Langmuir isotherm model fit better the equilibrium data of dyes adsorption. The maximum adsorption capacities determined from the Langmuir equation were 43.48, 32.68, and 3.51 mg/g, for CV, MB and OG, respectively.
In Vitro and In vivo approaches to evaluate Uncaria tomentosa bark extract loaded FDOFs on Osteoarthritis models
Authors: Sowjanya J. Naga , rao Raja
Published: June 2023

Osteoarthritis is one the leading health concerns worldwide affecting two third million with no proper treatment ensured to restore the normal function and completely relieving the joint pain. Oral fast dissolving films have promising action and targeted delivery with high drug loading capacity. The present investigation involves the study the invitro and invivo activity of developed Oral fast dissolving films of U. tomentosa bark extract with optimised F5 and F13 formulations. For invitro evaluation a three dimensional OA model was prepared with first passage chrondrocytes grown on trypsin EDTA media in 1: 3 ratio. The OA agarose model was prepared with C20A4 chondrocytes on agarose gel (25 ± 5oC) in phospahate buffer solution. Cultivation of chrondrocytes was done with 1 mL of RPMI-1640 (10% FBS) which was added with 20% (IL-1β) solution on third day of incubation and media was replaced time to time. The incubated cell line with 20,000 cells/well in 96-well plates were treated with 5 µL of 0.5% MTT reagent on fifth day of incubation and absorbance was measured at 570 nm. The effects were studied for 7, 13, 27, 35 days for the study effects of FDOFs on the cell lines were (Control, IL-1β, F5, and F13 treated IL-1β injected types). The chondrocytes in agarose constructs cultured only in media (RPMI-FBS) without IL-1b, served as control. The GAG, HYP and DNA quantitation analyses along with DNA content assay were performed to study the arthritic effect of optimized FDOF’s i.e F5. For invivo studies Monoiodoacetate (MIA) induced arthritis models which is well established to understand weight bearing and response to tactile stimuli though the ongoing procedure is not known. The invivo protocol was performed in seven week old male wistar rats with negative control of MIA and positive control as Celecoxib. The assessment of pain and thickness of the knee were estimated to be indicators of osteoarthritic potential. The study results revealed the F5 formulation has efficacy on the OA models which need a clinical investigation in humans.
Jejunal gastrointestinal stromal tumor that developed in a patient with neurofibromatosis type 1: a case report
Authors: Nagano Hideki , Ohyama Shigekazu , Sato Atsushi , Igarashi Jun , Yamamoto Tomoko , Kadoya Masumi , Kobayashi Mikiko
Published: June 2023

Background
Neurofibromatosis type 1 (NF1) is known to be associated with the frequent occurrence of unique gastrointestinal stromal tumors (GISTs). Whereas most sporadic GISTs occur in the stomach and possess mutations in the c-kit proto-oncogene or platelet-derived growth factor receptor-alpha (PDGFRA), NF1-related GISTs develop most commonly in the small intestine and are not accompanied by c-kit or PDGFRA mutations. NF1-related GISTs also have a high tendency for multifocal development, indolent nature, low proliferation activity and favorable prognosis.
Case presentation
A 41-year-old woman visited her local doctor complaining of menorrhalgia; a large mass was detected in her lower abdomen, and she was referred to our hospital. The patient had hundreds of skin warts and café au lait spots. Ultrasonography showed a large heterogeneous cystic mass with various echo patterns indicating fluid-fluid levels, solid compartments and multiple septations. Magnetic resonance imaging showed a multilocular cystic mass with liquid content exhibiting various intensities, including that of blood. A small round solid mass was also observed close to the cystic tumor. Contrast-enhanced computed tomography showed that the round solid mass showed strong enhancement in the early phase, unlike the cystic tumor component. Open laparotomy revealed a multicystic exophytic tumor measuring 11.5 cm originating from the jejunal wall, 20 cm distal to the duodenojejunal flexure. A solid tumor measuring 2.1 cm was also found on the anal side of the large tumor. We resected the short segment of the jejunum, including the two lesions. Microscopic findings revealed that the cystic and solid tumor consisted of spindle-shaped tumor cells showing little atypia with a fascicular or bundle arrangement. Nuclear mitosis was scarce. Immunostaining of the tumor cells showed positive staining for KIT and DOG1 and negative staining for S100 and desmin. The NF1 patient was diagnosed with multiple GISTs accompanied by intratumoral hemorrhagic denaturation arising from the jejunum. The TNM staging was pT4N0M0,
stage IIIA.
Conclusion
We report a case of GISTs associated with NF1 that showed clinical manifestations atypical of sporadic GISTs, had a jejunal origin, showed multifocal development and had few mitotic figures. The recurrence risk and survival prognosis of NF1-related GISTs have not been sufficiently clarified and remain to be elucidated.
Do domestic budgerigars perceive predation risk?
Authors: Wang Chang , Zhao Xueqi , Tao Baodan , Peng Jiaqi , Wang Haitao , Yu Jiangping , Jin Longru
Published: June 2023

Predation risk may affect the foraging behavior of birds. However, there has been little research on the ability of domestic birds to perceive predation risk and thus adjust their feeding behavior. In this study, we tested whether domestic budgerigars (Melopsittacus undulates) perceived predation risk after the presentation of specimens and sounds of sparrowhawks (Accipiter nisus), domestic cats (Felis catus), and humans, and whether this in turn influenced their feeding behavior. When exposed to visual or acoustic stimuli, budgerigars showed significantly longer feeding latency under sparrowhawk, domestic cat, and human treatments than with controls. Budgerigars responded more strongly to acoustic stimuli than visual stimuli, and they showed the longest feeding latency and the least number of feeding times in response to sparrowhawk calls. Moreover, budgerigars showed shorter feeding latency and greater numbers of feeding times in response to human voices than to sparrowhawk or domestic cat calls. Our results suggest that domestic budgerigars may identify predation risk through visual or acoustic signals and adjust their feeding behavior accordingly.
Efficient synthesis of 2’-deoxyguanosine by employing an engineered purine nucleoside phosphorylase from Brevibacterium acetylicum in one-pot cascade
Authors: Xu Lian , Li Hui-Min , Lin Juan
Published: June 2023

2’-deoxyguanosine is a key medical intermediate which could be applied for the synthesis of anti-cancer drug and biomarker in type 2 diabetes. In present study, an enzymatic cascade for the efficient synthesis of 2’-deoxyguanosine was proposed by employing thymidine phosphorylase from Escherichia coli (EcTP) and purine nucleoside phosphorylase from Brevibacterium acetylicum (BaPNP) in a one-pot whole cell catalysis. Semi-rational design of BaPNP was performed to enhance its activity, resulting a best triple variant BaPNP-Mu3 (E57A/T189S/L243I), with an overall 5.6-fold higher yield of 2'-deoxyguanosine as compared with BaPNP-Mu0. Molecular dynamics simulation revealed that the engineering of BaPNP-Mu3 led to a larger and more flexible substrate entrance channel, which might contribute to its catalytic performance. Furthermore, by coordinating the expression of BaPNP-M3 and EcTP, a robust whole cell catalyst W05 was constructed, which could produce 14.8 mM 2’-deoxyguanosine with a high time-space yield (1.32 g/L/h) and therefore was very competitive for industrial applications.
Morpho-biochemical responses of rice genotypes against leaffolder, Cnaphalocrocis medinalis, Guenee
Authors: Nayak Anjan Kumar , Golive Prasanthi , Sasmal Arundhati , Adak Totan , Kumar Gaurav , Dash Soumya Shephalika , Patil Naveenkumara B. , Mohapatra Shyamaranjan Das
Published: June 2023

Rice leaffolder, Cnaphalocrocis medinalis, Guenee is a serious pest of rice and causes significant yield losses. Insecticides are commonly employed to control this pest, but their use often escalates production costs and fosters pesticide resistance. Identifying insect-resistant rice genotypes and their resistance mechanisms is crucial for successful pest management. New sources of resistance providing long-lasting protection against leaffolder can be identified by studying the morphobiochemical characteristics of different rice genotypes. This study explored the role of various morphological traits of certain genotypes that confer resistance. Different biochemical constituents like soluble protein, phenol, total soluble sugar and enzymes viz., peroxidase, polyphenol oxidase and catalase were assessed spectrophotometrically in all infested and uninfested genotypes along with standard resistant (TKM6) and susceptible (TN1) checks. Leaffolder damage was negatively significant with plant height and leaf length (r = -0.903 and − 0.862, P < 0.001 respectively) while leaf width association was significantly positive (r = 0.773, P < 0.001). Among the different plant metabolites analyzed, total soluble sugar and soluble protein showed significant positive correlation (r = 0.778 and 0.788, P < 0.001 respectively) with leaffolder damage, conversely phenol (r = -0.651, P < 0.001) and antioxidative enzymes showed significant negative correlation. When rice genotypes were exposed to leaffolder larval feeding, they exhibited defence responses characterized by reduction in the level of sugars and proteins, accumulation of phenolic compounds and upregulation of antioxidative enzymes. This study emphasized the significance of morphobiochemical characteristics in rice resistance mechanisms against leaffolder. By leveraging these traits, new resistant rice germplasms against leaffolder can be developed.
Random acoustic noise
Authors: Banek Tadeusz Henryk
Published: June 2023

We introduce the concept of acoustic white noise (AWN) and then we get colored noiseas random sequences generated by dynamic systems (DS) with AWN input. Although DS isvirtual, the noise it generates can mimic real noise. Determining a system that generates agiven noise from white noise is called identification. We solve the task of identification bothfor noise-generating systems and for transmission channels. We also provide estimates for thecapacity of such channels using information theory concepts.
Rapid quantification of alcohol content in intact bottles of wine using J-coupled spectroscopy in an inhomogeneous low field magnet
Authors: Webb Andrew , Najac Chloe , Ronen Itamar
Published: June 2023

Direct spectroscopic quantification of small molecules using low cost, low field (< 0.1 Tesla) large bore portable magnets is not possible using conventional techniques due the presence of strong homonuclear coupling which results in complicated spectral patterns with resonances separated by much less than the achievable spectral linewidth. In contrast, a method using the signals from a Carr-Purcell-Meiboom-Gill (CPMG) train, in which the data are Fourier transformed in this indirect dimension, can produce so-called J-spectra in which several distinct spectral features can be distinguished. In this work we evaluate this technique to quantify the amount of alcohol (ethanol) in intact bottles of wines or spirits.
A case study on oil spills, coastal pollution, and the development of antimicrobial resistance in bacteria isolated from soil collected along the Arabian Sea and Bay of Bengal coastlines
Authors: Rekadwad Bhagwan Narayan , Shouche Yogesh S. , Jangid Kamlesh
Published: June 2023

Pelagic transport causes oil pollution by traversing the open ocean in southern Asia and Indian territory via international tanker routes. The natural flow of ocean water from east to west, which carries pollutants and biohazards into the marine waters belonging to the Indian territory, is what causes the deposition and saturation of oil spills, tar (i.e., hydrocarbons), and wastes in ocean waters. Water currents and tides carry tons of crude oil that has leaked from oil tanker accidents in the open ocean to coastlines. Negative effects such as the formation of algal blooms result in the death of marine animals such as fish, starfish, octopus, squid, and jellyfish. The consequences of pollution have mostly affected coastal areas, especially mangroves, and may destroy potential fishing zones. Long-term exposure to domestic and industrial pollution may be a cause for the loss of biodiversity and the development of antibiotic resistance in bacteria. Microbiological investigations have revealed the presence of hydrocarbon- and antibiotic-resistant bacterial taxa belonging to Bacillus, Domibaciluus, Acinetobacter, Brevundimonas, Streptococcus, Mycolibacterium, Spingomonas, etc. This reveals reasons for pollution in the seas and the development of antimicrobial resistance in microorganisms spreading across coastlines that pose a threat to public health.
Quasi-Static Levitation of Magic Squares
Authors: Fahimi Peyman
Published: June 2023

Magic squares are fascinating mathematical constructs that have captured the imagination of people for centuries. In this study, we investigate the behavior of electrically charged magic squares of order 4 under the influence of electrostatic forces. We treat the matrix elements of the magic squares as electric charges and numerically simulate their behavior using a dynamic controller. Our results demonstrate that the charges move towards a quasi-static equilibrium while preserving the original magic square arrangement and its magical properties. Additionally, the results reveal distinctive patterns in the displacement between the charges. Our study sheds light on the behavior of charged magic squares under electrostatic forces and provides insight into the physical properties of these intriguing mathematical constructs.
The effects of blended learning activities based on the ASSURE model in teaching on students and teachers in music lessons
Authors: İRMİŞ Sevim , ULUDAĞ Ali Korkut
Published: June 2023

This study, carried out during COVID-19, aimed at evaluating the effects of music lesson activities prepared with blended learning and the ASSURE instructional design model on both students and music teachers. 10th grade students (n=30) in a public school participated in the study. An action research design was prepared with a combination of learning at stations method, mobile games (Rhythm Cat, NoteWorks) and Web 2.0 tools (Thinglink, Plickers, Kahoot). “Teacher diary” and “semi-structured interview protocol” were used as data collection tools. The data were analyzed by content analysis with Maxqda software. Interrater reliability of the two experts asked to code the qualitative data was calculated to increase the reliability of the study. Following the implementation, the findings showed that the students’ independent learning, motivation, collaboration, making learning fun, interaction, communication, competition, socialization and productivity improved intensively. It was understood that the emerged negativities were not related to the teaching tools used in the action research procedure but were generally related to the negative learning conditions due to the pandemic. The most notable negative aspects were difficulty in technological competence, difficulties in self-regulation, temporary anxiety, digital access and some short-term technological malfunctions. The study concludes with several recommendations and highlights the points that need further attention in such innovative research.
STUDY OF NEW ONSET TYPE 1 DIABETES AMONG CHILDREN BEFORE AND AFTER COVID 19 PANDEMIC IN A TERTIARY CARE SETTING
Authors:   Resident of Department of Paediatrics., Sivamani Divya , R. Premalatha ,   Professor& HOD of Department of Paediatrics,- MVJ Medical College And Research Hospital.
Published: June 2023

Background: On March 11, 2020 the WHO announced a coronavirus disease 2019 (COVID-19) pandemic. Lockdown restrictions, compromised access to medical care and fear of potential exposure to SARS-CoV-2 have forced patients with non-COVID-19 illnesses like type 1 diabetes (T1D) to stay home. This situation lead to delay in T1D diagnosis and treatment resulting in rapid progression to diabetic ketoacidosis (DKA) and therefore increased risk of complications and death Objective: To compare between frequency and characteristic of new onset of T1D in children before and after pandemic. Methods: This retrospective cohort study comprises 2 datasets- children diagnosed with new-onset T1D and admitted in MVJ medical college prepandemic from 1sep 2017 to 29 feb 2020 and pandemic from 1 march 2020 to 30 august 2022. We compared frequency and characteristics of children with newly diagnosed T1D before and after pandemic. Results: The number of children admitted to MVJ medical college due to new-onset T1D prepandemic were 9 cases which increased to 25 cases during the study period, with most of children had severe DKA during and after COVID-19. Conclusion: Most of children who admitted with T1D had severe DKA at diagnosis during the pandemic in comparison to prepandemic. The main stems for increase case and severity is delayed diagnosis following changes in parental behaviour and healthcare accessibility and another probability would be viral infections triggering T1D and/or DKA during pandemic. However, it needs to evaluate potential effects of SARS-CoV-2 on increased percentage of new onset T1D.
MODELING AND FORECASTING OF THE VOLATILITY OF ALL-SHARE INDEX OF NIGERIAN STOCK EXCHANGE MARKET
Authors:   Department Of Industrial Mathematics and Applied Statistics Ebonyi State University, Abakaliki, Ebonyi State, Nigeria., E.I. Onyishi , Okoro. C.N. ,   Department Of Industrial Mathematics and Applied Statistics Ebonyi State University, Abakaliki, Ebonyi State, Nigeria., E.O. Ibina ,   Department of Mathematics and Statistics, Akanu Ibiam Federal Polytechnic, Unwana Afikpo. Ebonyi State.
Published: June 2023

This paper modeled and forecasted the volatility of the Nigerian Stock Exchange Market while incorporating trade volume from January 2022 to December 2024 using both symmetric and asymmetric volatility models such as ARCH, GARCH, GARCH-M, EGARCH, TGARCH, and PGARCH each in Normal, Students-t and Generalized Error Distributions. The results revealed the following facts: the volatility of the market returns could best be modeled using PGARCH (1, 3) model in normal error distribution, there is evidence of positive leverage effect which reflects that positive shocks induce a larger increase in volatility when compared to the negative shocks of equal magnitude, news about volatility from the previous periods has an explanatory power on current volatility, there is volatility clustering in the market returns, changes in the market returns are explosive, the market risk and returns are inversely related, and the out-sample forecast of the market volatility for the next 2years shows that there will be a low volatility from March to September of the year 2023 and then an increase in volatility up to December 2024. However, for policy and investment decision the paper recommends taking the news on volatility into consideration while forming expectations in the market, investors could invest more within March to September 2023 as the market risk and returns are inversely related, following the forecast estimate that the volatility will be on increase from October 2023 up to December 2024 within which investors are likely to invest less as the market risk and returns are inversely related monetary authority could contract the money supply so as to control the problem of idle cash if the percentage of the investors in the risk-averse category is greater than that of risk-lovers and risk diversifiers categories.
COMPONENTS OF EDUCATION IN FACING AN EPIDEMIC: A STUDY ACCORDING TO PROPHETIC NARRATION
Authors:   Senior Lecturer, Academy Contemporary of Islamic Studies (ACIS) UniversitiTeknologi MARA (UiTM), Shah Alam., Binti Izham Siti Sarah , Nor Amira Mohamad Siti ,   Senior Lecturer, Academy Contemporary of Islamic Studies (ACIS) UniversitiTeknologi MARA (UiTM), Shah Alam., Said Shahirah ,   Senior Lecturer, Academy Contemporary of Islamic Studies (ACIS) UniversitiTeknologi MARA (UiTM), CawanganPulau Pinang., Simbolon Parlindungan ,   Senior Lecturer, Sekolah Tinggi Agama Islam (STAI)Al-Kifayah Riau., Mazlan Najmuddin ,   Posgraduate Student, Academy Contemporary of Islamic Studies (ACIS) UniversitiTeknologi MARA (UiTM), Shah Alam.
Published: June 2023

A plague is a disease that spreads quickly and easily infects anyone. Guidance related to the epidemic, its transmission, how to overcome it and the role of individuals and society have been mentioned for a long time. The proof can be seen through authentic hadiths. However, even if the guidance is available in the hadith if it is not taught and educated, then it cannot be practised in life. Therefore, the main goal of this study is to analyze and issue guidance found in the hadith and then discussed it from the educational aspect. This study will use the J.E.R.I method, which means the discussion will be debated using physical, emotional, spiritual and intellectual keywords. This study is qualitative, which is a data collection method from library research. The main data analysis method used is to analyze the content found in the sahih book of al-Bukhari which is in the chapter of al-Tibb and the authentic book of Muslim in the chapter of al-Salam. While the analysis of the study is descriptive. The results of the study found that there is a complete guide shown by the Prophet s.a.w. through his sunnah which can be issued as an element of education that includes physical, emotional, spiritual, and intellectual aspects. This guide can be a reference for various parties including the public itself when dealing with special situations during an epidemic.
Pedagogía Franciscana como capital heredado desde los campos de Bourdieu
Authors: Barragán-Giraldo Diego Fernando , Guerrero Lucero Maura Andrea
Published: June 2023

La investigación asume el enfoque cualitativo. La información se obtuvo a partir de talleres, diarios de campo y autorrelatos de docentes participantes, representantes de 19 programas de pregrado de la Universidad Mariana, Pasto. El análisis se realizó mediante categorías deductivas e inductivas, de donde se extrajo las proposiciones que dan consistencia a la comprensión de la pedagogía franciscana desde la teoría de los campos de Bourdieu. El aporte logrado se resume en una mirada integradora y novedosa de la pedagogía franciscana, la resignificación de las prácticas pedagógicas de los docentes, a partir de relatos y experiencias que configuran el corpus teórico de la constitución del campo, capital y habitus, desde la perspectiva franciscana para la formación en capacidades humanas.
Estrategias de cortesía para una argumentación de la fraternidad en la carta a Filemón desde un enfoque pragmadialéctico integrado
Authors: Salazar Parra, SJ Juan
Published: June 2023

El registro de la personalidad de Pablo, su formación intelectual y su misión hacen de él un hombre de controversias y de originalidades en su discurso. Este artículo pretende describir: (a) la estructura argumentativa de la llamada 'carta a Filemón' (Fm), texto considerado de autoría paulina, y (b) las maniobras estratégicas que desarrolla el autor del documento para resolver la discusión crítica, específicamente a partir del uso de estrategias de cortesía verbal. En términos generales, desde un análisis dialéctico, la carta nos presenta el pedido del prisionero para que Filemón reciba a Onésimo de regreso en su casa, así como los argumentos que favorecen esta postura. Al insertar las maniobras estratégicas, es decir, el elemento pragmático y retórico, se puede observar un cambio en el punto de vista y en el argumento. Las estrategias de cortesía verbal ayudan, por un lado, a que la comunidad acoja a Onésimo y, por otro lado, aprenda que los cristianos han sido generados por la fe en Cristo. Por tanto, no sólo se declara la petición, sino una nueva verdad de fe y una práctica de vida eclesial y social. Pablo salvaguarda la imagen negativa, apelando a un nuevo estilo de autoridad y a una renovada forma de vida comunitaria que va más allá del contexto específico en el que fue escrita la carta. Todo hombre y mujer de fe son miembros dignos de la comunidad porque son “mis entrañas” (Fm 12b).
Hubungan E-Wom, Consumer Ethnocentrism, Brand Equity dan Purchase Intention pada Sepatu Merek Indonesia
Authors: Skiefer Nicholas , Suwandi Caroline , Rahman Fathony , Sumarlin Antonius W.
Published: June 2023

Amidst the flood of imported goods from China over the past 20 years, the Indonesian government launched the national movement called Bangga Buatan Indonesia (Gernas BBI). This phenomenon provides an opportunity to generate consumer ethnocentrism and brand equity to help Indonesian SMEs improve their loyalty and competitiveness towards their brands. This study builds on previous research on the relationship between e-wom, consumer ethnocentrism, and brand equity, by replacing brand equity to make it more relevant and adding purchase intention to determine which factors can drive purchasing interest and what motivates that interest. To make this study more relevant to the current situation, the researchers also adopted a theoretical study. SEM analysis was conducted with 320 respondents using non-probability techniques. The results showed that positive e-wom has a greater influence on the purchase intention of domestic shoe brands. To compete against foreign shoe brands, owners of domestic shoe brands must rely more on positive e-wom than consumer ethnocentrism.
Efficient, Green One-Pot Synthesis of Antimicrobial Agents: Functionalized
DPTS Catalyst for the Preparation of 2-Amino-4-Aryl-5-Oxo-4HChromene-
3-Carbonitriles, with Theoretical Calculations
Authors: Beldi Razika , Aimene Nadjet , Barhouchi Badra , Zouchoune Bachir , Boulcina Raouf
Published: June 2023

Background:

In the search for a new and effective synthetic approach to bio-logically chromene-derived compounds, a series of 2-amino-7, 7-dimethyl-5-oxo-4H-tetrahydrochromene-3-carbonitrile derivatives (4a-i) were synthesized. This synthesis involved the use of 4-(dimethylamino)pyridiniump-toluenesulfonate (DPTS) as a catalyst in an aqueous medium. Additionally, the relative stability between isomers was investigated using DFT/B3LYP calculations.

Methods:

The target compounds were synthesized through a multicomponent reaction of 5,5-dimethyl-1,3-cyclohexanedione (dimedone) 1, various arylaldehydes (2a-i), and malononitrile 3 in water and were recrystallized in ethanol. The reaction was promoted using DPTS, which is a low-toxic, inexpensive, commercially available, and easy-to-handle catalyst.

Results:

The catalytic activity of DPTS was investigated in a condensation reaction conducted in an aqueous medium at room temperature. All synthesized compounds displayed considerable antimicrobial activities against human pathogenic bacteria and fungi.

Conclusion:

The developed synthetic protocol demonstrates energy efficiency, shorter reaction time, environmental friendliness, high product yields with purity, and scalability to gram-scale synthesis. DPTS proved to be a valuable contribution to the field of organocatalysis. The synthesized compounds were screened for in vitro antimicrobial activities, demonstrating varying potency against the microbial strains. Compound 4h exhibited the most potent activity with a zone of inhibition (ZOI) measuring 15 mm against E.coli. This was followed by compounds 4b, 4d, 4f, and 4g, which displayed a ZOI of 12 mm. Furthermore, the antifungal results revealed promising anticandidal activity for compounds 4b, 4e, and 4h, with a lower minimum inhibitory concentration (MIC) of 0.031 mg/ml. In addition, molecular electrostatic potential (MEP) mapping, reactivity indices such as electronegativity, electrophilic index, softness, and hardness, as well as frontier molecular orbitals (HOMO-LUMO), were used to provide further evidence regarding the stability and reactivity of the synthesized products.
A Review and Comprehensive Study on DC-DC Converters
Authors: Anusha Dharavath , P. Srinivasan , K. Narender Reddy
Published: June 2023

Background:

DC-DC converters are used in various applications based on their required
voltage capabilities ranging from milli volts to thousands of volts.

Methods:

This review paper discusses various voltage boosting techniques, such as buck-boost,
switched inductor, switched capacitors, isolated converters, etc., and provides a detailed evaluation
of the literature and comparison of different DC-DC converters.

Results:

This study reports a number of storage elements included, such as inductors and capacitors
as well as switches and diodes. Their features along with methodologies, merits, complexity,
efficiency, and voltage gain have been tabulated. A comprehensive study, converter classification
based on the characteristics, and a detailed analysis of isolated and non-isolated DC-DC converters
have also been provided.

Conclusion:

As this study provides a comparison of each isolated and non-isolated converter's
comprehensive gain, this research may help in future topology optimization for the choice of the
ideal converter for applications. In addition, the examination of each isolated and non-isolated
converter's comprehensive gain comparison has also been presented in this paper.
Psychological contract, auditor deviations and audit quality
Authors: Sunti Lodovikus X
Published: June 2023

This article is designed to explore the theme: “Psychological Contract, Auditor Deviation, and Audit Quality Which is reviewed from the point of view of non-public accountants. This theme was lifted from the results of research conducted at a company in Surabaya, East Java, Indonesia. Moreover, this study aims to examine the relationship between psychological contracts, Dysfunctional Auditor Behavior, and Audit Quality. This research was taken place at the Non-Big category of Public Accounting Firms or not affiliated with the Big Public Accounting Firms located in Surabaya, East Java, Indonesia. The subjects of this study were supervisory level auditors with the assumption that they had understood and experienced in implementing audit procedures and how they understood the work environment, work relations, and leadership. Researchers use psychological contract variables as independent variables, the variable Audit Quality as the dependent variable, and the Dysfunctional Auditor Behavior variable as the mediating variable. Statistical testing using simple regression to prove the three hypotheses proposed by researchers. The results shows that the psychological contract has a negative effect on dysfunctional auditor behavior and it also can negatively effect on the audit quality. In contrast, the Psychological Contract can positively influence on the audit quality.
O Jardim das Amoreiras e o resgate da memoria de Seropédica/RJ no fio da seda: um projeto de extensão no Jardim Botânico da UFRRJ
Authors: Barros Regina Cohen , Silva Gabrielle Evangelista da , Vargas Karine Bueno , Sampaio Andrea Carmo , Lorenzon Maria Cristina , Moura Maria Veronica Leite Pereira
Published: June 2023

The importance of recovering the memory of places and their legacies is contributing to the (re)signification of society's identity and its valuation. The “Mulberry Garden” is an extension project developed with the objective of recovering a little part of the history of the Seropédica municipality, whose name derives from sericulture (the cultivation of the silkworm), an activity developed there in the middle of the 19th century. The arboretum, planted in the Botanical Garden located on the campus of the Federal Rural University of Rio de Janeiro, intends to be a space to rescue a bit of local history and explain what sericulture is, through a series of objects and actions, as an educational guided trail, open to the community. The project is developed in partnership between the Departments of Geography, Animal Production and Botany and UFRRJ Technical School. The UFRRJ's Botanical Garden was chosen because it is a unit that performs research, teaching, extension, conservation, and enhancement activities for botanical species; with multi and interdisciplinary perspectives, helping to rescue the memory of the municipality through planting mulberry trees (Morus alba L., Moraceae), an exotic species whose leaves are the food of the silkworm (Bombyx mori L., 1758; Lepidoptera: Bombycidae). The “Mulberries Garden” occupies an area of 70m2, consisting of three alleys of mulberry trees delimited by a lawn whose boundaries reproduce, in scale, the territoriality of Seropédica. In addition, the Project aims to develop teaching materials and promote activities with schools, the local community, and the university community. Through visitation, observation and experimentation of materials, a bit of the city's history is recovered, delving into its past (in geological, biological, and historical times) until the present day. In another way, the creation of the “silkworm” and the production of silk thread are also rescued and publicized, as sustainable activities that can unfold into other ventures.
A despesa em Portugal: escolhas e conflitos
Authors: Teixeira Glória , Moura António Graça , Castro Leonor , Oliveira Lucas , Andrade Matilde , Correia Afonso , Azevedo Valéria
Published: June 2023

This article aims to explain the concept of public and private expenditure in Portugal, to present its trends in recent years and emphasize future challenges that shall take into account the ageing population and the public and private investment levels. It raises awareness to the need of an increased fiscal discipline and an adequate implementation of economic policies based upon a civil society with enhanced technological and digital skills