bluuebunny/crossref_metadata_2025 huggingface dataset:
CIVIL-MILITARY INTERACTION TO ORGANIZE A MEDICAL EVACUATION SUPPORT OF THE ARMED FORCES OF UKRAINE
Authors: Karamyshev D. V. , Hordiienko L. P. , Lytvynenko M. I.
Published: December 2023

Abstract. The article studies the complex problem of formation and development of civil–military interaction in the field of organization of medical evacuation support of the Armed Forces of Ukraine in the conditions of a unified medical space functioning. The purpose of the study is to substantiate conceptual provisions, generalize organizational and legal principles and methodological approaches, and formulate proposals for arrangement the activities of civil–military interaction structures in the direction of solving a complex of interdepartmental issues regarding the organization and development of the system of medical evacuation support of the Armed Forces of Ukraine.
It was found that an effective tool for solving the problems of medical evacuation support of the Armed Forces of Ukraine is the introduction of effective mechanisms of civil–military interaction and the adjustment of the activities of the relevant structures, which includes the formation of the organizational and legal foundations of such interaction in the context of the implementation of the Military Medical Doctrine of Ukraine and on the basis of a clear understanding of the operational needs in the medical evacuation support of the troops in the conditions of martial law.
It has been established that the need for integration into the unified medical space of Ukraine involves the construction of an integral system of medical evacuation support for the troops in combination with the resource capabilities of the civilian health care system, and also determines the unity of views on the organization, tactics and procedure for the use of forces and means of medical services and ensures the capacity of civilian health care facilities for medical evacuation support of military personnel, which is an important military medical factor of such cooperation.
A clear understanding of the capabilities of the medical evacuation support of the Armed Forces of Ukraine based on specific approaches is offered, which should include those that will contribute to the management of medical evacuation support at the appropriate levels; conducting effective medical evacuation measures and appropriate support, as well as medical protection measures for the personnel of the troops, etc. The importance of defining and clearly demarcating levels of medical care and necessary resources has been proven, which will provide an opportunity to work out real interdepartmental civil–military interaction and establish a system of medical evacuation support for servicemen of the Armed Forces of Ukraine in the conditions of the unified medical space.
LEGAL INSTITUTIONALIZATION OF PUBLIC GOVERNANCE WITHIN RECENT SOCIAL TRANSFORMATIONS
Authors: Kovalova T. V.
Published: December 2023

The article substantiates the expediency of applying the neoinstitutional approach to the study of legal institutionalization processes under the conditions
of social changes, defines the role of legal institutionalization in public governance considering
some factors promoting or, on the contrary, hinder effectiveness of legal institutions.
The neo-institutional approach is a relevant methodological basis for the study of the
development of the legal system under the conditions of social transformations and reforming of
state administration. In the concept of formal institutionalization, legal institutionalization means
the formation of new legal institutions, the formalization of certain social relations and social ties.
However, revealing the essence of legal institutionalization from the formal side is far from the only
approach related to the perception of institutionalization as a law-making phenomenon. In opposition
to the concept of formalization, ideas about the decisive role of the substantive component in the
institutional process are put forward. According to this theory, the creation of legal institutions does
not depend on their formal recognition by the legislator. This actually means that legal institutions
are formed and developed in parallel with regulative legal acts, but the form of law is not perceived
as an indicator of the existence of one or another institution. The basis of institutionalization
is the legal relation itself which is combined into certain types based on systemic features In connection to the expansion of the essence of legal regulation, the purpose of legal
institutionalization has changed. As a result, it is possible to explain the emergence of numerous
institutions which do not have any formal legal consolidation. In order to understand the nature and
logic of the development of institutions, it is necessary to study the factors that guide society, citizens,
and social groups in their actions, that is, to study institutions. The success of institutionalization
mainly depends on national specifics and the state of socio-economic development of the country.
The article has a theoretical-methodological character, and the material presented in it can
be the basis for the study of legal institutionalization in various spheres of public administration.
GENDER ANALYSIS IN THE MANAGEMENT OF SOCIAL DEVELOPMENT IN THE CONDITIONS OF RUSSIA’S ARMED AGGRESSION AGAINST UKRAINE
Authors: Sychova V. V. , Honiukova L. V.
Published: December 2023

Аnnotation. The article is devoted to the study of the application of gender analysis in the
management of social development in the conditions of Russia’s armed aggression against Ukraine.
It was substantiated that gender analysis should be more widely applied outside the political decisionmaking process. Further development took place using the “3 P method” for the analysis of problems
and features of public management of social development in the conditions of war was further
developed. This allows us to consider gender analysis as a tool for managing social development in
the conditions of the Russian-Ukrainian war.
It was revealed that the horizontal gender segregation of labor inherent in Ukraine has
deepened since the 1990s, and after the evacuation/emigration of girls and women in the course
of large-scale Russian aggression, it led to regressive social development. This is confirmed by the
temporary suspension of the work of most authorities in the field of social protection, state/municipal
institutions, structures in the social sphere, the closure of a significant number of medical institutions,
pharmacies, the deterioration of the quality/reduction of the number of social services. It was
established that in the conditions of the Russian-Ukrainian war, the horizontal gender segregation of
labor in the social sphere created threats to the direct public management of social development. Under
extraordinary conditions, the importance of horizontal communicative interaction, communicative
management in the social sphere of society has increased.
It has been proven that the Russian-Ukrainian war made it impossible to reproduce and
improve human capital, and worsened the quality of health of the Ukrainian population. The murders
of civilians by the aggressor country, the significant excess mortality of men in reproductive age, the
consequences of sexual violence against women and girls by Russians in the occupied territories
undermine the public health system, threaten the loss of the reproductive potential of the Ukrainian
nation. It was found that the deliberate destruction of civilian objects (especially social infrastructure)
by shelling from Russia worsened the financial situation of all Ukrainian citizens, but to a greater
extent women.
It is suggested, that the priority direction of social development management should be state
management of public health protection after the war.
New traces of regulation of information platforms and a platform-based economy for the new public good
Authors: Dunayev Ihor , Kovalenko Mykola
Published: December 2023

The paper offers the authors’ vision of a new problem for Ukraine, but not new for the Western and Eastern world – how to regulate some rising information platforms and the platform-based economy. The purpose of this article is to critically analyze the current global practice of public regulation of information platforms and, based on this, to determine new trajectories of their regulation for the greater public good and renewal of public administration.

The step-by-step logic of the presentation of further material in the article is as follows: 1) critical generalization of the essential effects of information platforms for the economy and public administration; 2) modern transformations in the essence of the platform economy; 3) an overview of the essence of the existing state regulation of platforms, which departs from the regulation of purely competition, and is more aimed at the regulation of socio-economic development, 4) clarify the state and supranational regulatory approaches to platforms and the directions of their changes now in the Western world.

In general, the paper is a continuation of the ongoing broad expert and political debates about what, how and who to regulate in the new platform environment, the participants of which are or soon will be almost all people. The authors pay considerable attention to the overview of regulatory issues, practices and approaches, and in particular to the latest European laws on digital markets and digital services. Together, these two laws establish a new trend to regulate not only competition, but also very broad socio-economic processes in countries that have already encountered practical difficulties in social transformations and conflicts, and this process will definitely not be quick.
Public governance of environmental protection activities in a collective security system: current threats to Ukraine and proper responses
Authors: Biryukov Vadym
Published: December 2023

The paper pursues more critical generalization of threats and risks in the field of environmental protection activities in the conditions of armed aggression against Ukraine, and, accordingly, to clarify the institutional conditions for the introduction of the best international experience for the prevention and minimization of possible consequences in the spheres of national security and defense.

The strategic priority for the modern development of the country should be ensuring the environmental safety of people, society, and the state. The demands of the modern world leave no chance for Ukraine to study as widely as possible the international experience in the field of public administration and environmental protection activities in the system of collective security. The study of problems in the system of environmental protection supervision showed the interrelationship and interdependence of all factors, components, directions and mechanisms of formation and implementation of state policy in the system of national security and defense. There is an urgent issue regarding the need to create conditions for ensuring environmental security in the system of the Armed Forces of Ukraine in order to protect national interests in the activities of business entities of the military-industrial complex.

The reasons for them are the shortcomings of public management and the manifestation of potential changes in the environmental sphere. Military events related to Russian aggression against Ukraine also complicate the situation in this area. Both internal and external threats and risks to national security and defense do not arise without good reasons. The implementation of priority areas of state regulation of environmental protection activities requires consistency, systematicity and comprehensiveness of their introduction, and environmental intelligence is the foundation for the construction of the entire structure, it provides for the prevention and minimization of the occurrence of threats and risks in the spheres of national security and defense.
Principles of regional self-government according to Council of Europe reference framework for regional democracy
Authors: Sakhanienko Sierhiei , Kolisnichenko Natalia , Drobot Ihor
Published: December 2023

The purpose of the article is to determine the general principles of regional self-government in accordance with the Framework recommendations of the Council of Europe on regional democracy. Ingenerak, this paper is intended to the content of Council of Europe Reference Framework for Regional Democracy, which in general form contains European standards of regional self-government, is examined. For a more complete presentation of the Reference Framework, the regulative acts of the Council of Europe relating to regional self-government were studied.

The Reference Framework is presented as a means of transcending the scope of the European Charter of Local Self-Government in order to help governments strike the best possible balance in the apportionment of powers and responsibilities among different tiers of government. The Reference Framework is also analyzed on the basis of the principle of subsidiarity, the principle of social and territorial cohesion and the need for solidarity.

The nature and principles of regional democracy are revealed. The characteristics of local and regional authorities which reflect the key principles of democracy and public participation in the management of living environments are examined. It is concluded that the essence of the principles of democracy constitute the combination of all principles and «rules for living» within a state.

A comparison of the European standards of regional self-government with the regulatory practice of self-government functioning at the level of the regions of Ukraine has been carried out. The author’s vision on the introduction of regional self-government in Ukraine is presented.
Public administration using blockchain technology and platforms: new opportunities
Authors: Dziundziuk Viacheslav , Dziundziuk Boris
Published: December 2023

This article aims to identify potential applications of blockchain technology in public administration. Although blockchain is most useful when trust in government is low (because blockchain provides greater accountability), the feasibility of implementing blockchain solutions depends on a certain level of administrative and technical capacity of the authorities and, most importantly, on their readiness and willingness to implement these technologies. depends on the following factors. The reluctance to implement blockchain technology is partly related to the perception that blockchain is in “competition” with the state. There are also “usual” political barriers to change in administrative structures, such as the reluctance of government officials to introduce new technologies.

The analysis showed that blockchain technology has not yet become widespread in the public sector, although a number of pilot programs have been developed. In addition, many applications of blockchain have not progressed beyond proof of concept and pilot implementations on a limited scale, and further research is needed on the barriers to the adoption of blockchain technology in the public sector, including the issue of the so-called “digital divide”.

We know that the consideration of blockchain in public administration can be divided into one or more of the following perspectives: blockchain as a technology of freedom, blockchain as a polycentric structure, or blockchain as a new type of database. Each perspective sheds light on its potential for public sector governance, as blockchain can be all three, depending on the political, economic, social and technological context.

The article also identifies that personal data, government procurement, online government services and support for democratic processes are areas where blockchain technology can be successfully used to improve administrative efficiency. However, the analysis also proved that blockchain offers opportunities in almost all areas of public administration, so a special program for implementing blockchain technology in the public sector is needed.
Public administration and politics: correlation of theoretical concepts in historical retrospect
Authors: Grybko Olha
Published: December 2023

The article analyzes the classification of the relationship between politics and administration, it was found that four models are distinguished according to the degree of interrelationship: classical, bureaucratic, deliberative, and hybrid. The formation and characteristic features of each model are considered. It was singled out a number of advantages of the hybrid model and given four main reasons that recommend its use: 1) provides an innovative (non-rationalist) view of the political process; 2) integrates policy and administration; 3) is sensitive to the complex nature of public policy; 4) it has the potential to deepen the democratic process.

In modern socio-economic conditions, the Ukrainian system of public administration has not yet found an optimal relationship between politics and administration, there is no clear separation of administrative and political functions. The reality of public administration shows that Ukraine lacks professional administrators-managers, free from the “pressure” of politics, as well as politicians who understand administrative mechanisms. However, the science of public administration was conceived as a technical way of solving social problems, which allows people to avoid the pitfalls of politics. It can be said that society would have better life if the collective decision-making process was devoid of political mediation and instead based solely on scientific approach.

Although even in this case, it is worth remembering that public administration, which is guided by the instrumental type of rationality, does not allow civil society (which is based on the communicative type of rationality) to have a significant impact on administrative activities.

Therefore, in our opinion, the best way to combine such similar and at the same time different phenomena as politics and administration is the method proposed by the hybrid model, because it defines: a) that public administration performs both administrative and political tasks; b) the political process as a continuous dispute that is never resolved forever, the hybrid model is adapted to the increasingly complex conditions of policy formation.

After all, the hybrid model notes the coexistence of several views; it allows political subjects to express their disagreement through political centers. By identifying conflict in the political process, the hybrid model promotes the development of democratic practices and institutions. Dissent, rather than binding consensus, is indispensable for revitalizing democratic processes and eliminating the “democratic deficits” that pervade modern societies.
State regulation distribution of false information in the media space: foreign experience
Authors: Gryn Dmytro
Published: December 2023

This paper focuses on necessity to regulate public relations regarding public figures related to defamation issues in the media space. The paper examines the experience of the countries in regulating defamatory content in the media space in general and in relation to public figures in particular.

Results of this research are consistent with by the fact that a public figure is indeed limited in his right to respect for honor, dignity and business reputation, but is not deprived of such rights, which provides grounds for legislative consolidation of the protection of the honor, dignity and business reputation of a public figure from defamatory statements in the media space.

This article established a connection between information activities on the Internet and defamation disputes regarding public figures. Such a connection consists in the presence in such information of public interest and, as a result, defamatory information causes public resonance.

In the process of researching was established that national and European courts, considering each defamation case separately, developed certain conclusions that are guided by the resolution of defamation disputes regarding public figures.

Using the example of countries such as Germany, Norway, France and Sweden, it was found that the way to settle disputed defamatory relations involving a public figure is to designate a public figure as a special subject of the said legal relations. In general, this research shows problems of the potential of the right to freedom of expression in the conditions of the functioning of the global Internet network, together with the need to timely regulate such social relations in the Internet network in order to protect the right of other persons to respect their honor, dignity and business reputation.

Account the existing world experience, in article formulated recommendations on the regulation of public relations in order to reduce the level of defamation in the media space regarding public figures. With the adoption of the relevant legislative changes, the issue of defamatory content in the media space regarding public figures can be comprehensively resolved, and the relevant relations can be settled in a timely manner.
Public administration of employment of the population of rural territories under the conditions of marital state and post-war reconstruction
Authors: Babaiev Valerij , Babaieva Iryna
Published: December 2023

The scientific study highlights the general situation that has developed under martial law, namely mass migration of the population, reduction of the economically active population, reduction of labor and educational potential, significant civilian casualties, and an increase in the number of people with disabilities and psycho-emotional disorders.

Attention is focused on the importance of the effectiveness of public policy in solving issues of promoting employment of the population, creating jobs, promoting self-employment and the development of entrepreneurship. The activities of local self-government bodies, namely, united territorial communities, regarding the solution of urgent issues regarding their functioning in new conditions, and especially meeting the needs of the army, accommodation of relocated enterprises, life support for internally displaced persons, formation and distribution of humanitarian aid, etc., were considered.

The need to replace the passive measures of the state employment policy with active ones has been proven, namely, assistance in promoting employment through retraining, opening one’s own business, training, etc. It is substantiated that the development of employment in rural areas is possible through the support of non-agricultural activities, provided that there are no other agricultural areas of employment in the settlement.

The advantages and disadvantages of the government program for the relocation of enterprises, the “eRobota” project, are considered, and the attention is focused on the effects of these programs both for the territory of the country as a whole and for rural territorial communities in particular. A method of solving the problem of agrarians regarding the disruption of logistics processes and transport connections by creating agro-logistics hubs is given.

It is proposed to create multifunctional cooperative and communal procurement and sales points to support rural entrepreneurship and self-employment.
National legal regulation of the digital economy and information platforms
Authors: Dunayev Ihor , Orlov Oleksandr
Published: December 2023

This article serves as a logical continuation of the authors’ series of publications on the public regulation of information platforms and platform economies. The objective of this article is to provide a concise summary of the rich international experience in national legal regulation of the digital economy and information platforms while identifying pertinent models of such regulation. It further contributes to the ongoing extensive expert and policy debate regarding what, how, and whom to regulate in the new platform environment, in which nearly everyone participates or will soon be involved. Drawing on a comprehensive analysis of legislation in foreign jurisdictions, the article highlights and elucidates three main models of legal regulation for the digital economy, using examples: the model of legislative regulation of the digital economy, the national strategic model, and the regional strategic model. The conclusion is drawn that Ukraine exhibits significant features that largely correspond to the first model. Such a model may involve the creation of specific legislation aimed at digital sector development, stimulating innovation and supporting startups. Nevertheless, Ukraine has already begun to encounter limitations associated with this model, as the digital economy evolves more rapidly than the government and legislators can adapt the legal framework to the latest changes, resulting in regulatory gaps.
Modern approaches to global and governmental regulation of virtual assets: what to choose to support digital innovations?
Authors: Kud Aleksandr
Published: December 2023

The paper offers a critical outlook at modern approaches to supranational and governmental regulation of the circulation of virtual assets, which have already developed with confidence and which actually determine the conflict between generally global and national views on a very heterogeneous category – virtual assets. The purpose of this article is to summarize some key regulatory approaches spread globally – from global to state levels – regarding the circulation of virtual assets and their critical analysis from the point of view of supporting digital innovation in a national economy.

The paper is a continuation of the ongoing wide-ranging expert and political debate about what government officials and presidents should be guided by in matters of circulation of virtual and, in particular, backed (secured) tokenized assets.

The logic of the presentation and judgments in the paper is related to the step-by-step consideration of such issues: (1) the basic political approach of the International Monetary Fund and its discussion from a public-management point of view; (2) institutional and administrative risks for governments regarding the full implementation of the IMF’s 2023 policy recommendations on the regulation of virtual assets; (3) widespread standards for the prudent (prudential) circulation of virtual assets, which were developed by other authoritative supranational organizations; (4) an overview of key problems in the coordination of multi- and single-level approaches to the regulation of virtual assets; (5) highlighting 5 regulatory approaches in the ways and scope of governmental (national) regulation of virtual assets currently operating in the world; (6) author’s comparison and assessment of regulatory approaches; (7) assessment of Ukrainian prospects in supporting technological innovations in the field of circulation of virtual assets in the context of the adoption of the new law «On Virtual Assets» in 2023.

The author makes the final conclusion that, generally, modern regulatory efforts of supranational and state regulators in the field of circulation of virtual assets are mostly focused on the problems of illegal financing, unfair competition and the integrity of new and old markets of financial assets, as well as focused on requirements for experience and financial stability of private service providers in the field of virtual assets. However, there is a growing understanding that regulators will arrive at a more or less single or multiple regulatory approach, which will be set at the supranational level, and this will only facilitate technological innovation. Such an approach will most likely be combined – based on regulatory flexibility and on the basis of principles (expected results).
Building effective governments in developing countries: from a global goal to intelligent action (experience of Brazil)
Authors: Gazarian Svitlana
Published: December 2023

The problem of creating effective governments in developing countries within the framework of the existing global system, while protecting their sovereignty and national power, is studied. An interdisciplinary approach to the study of the topic is highlighted. It is shown that the answer to the search for objective criteria for evaluating the results of administrative activity, which would testify to its effectiveness, is currently considered to be the Good Governance concept. One of its key principles is the principle of effectiveness, which consists in achieving the maximum possible positive result in accordance with the needs of society, given the most rational use of resources. An analysis of the effectiveness of the Government of Brazil, which has undergone repeated attempts to reform public administration, has been made. However, bureaucracy still remains one of the biggest problems of the state. It was noted that in the countries of Latin America, the reforms implemented under the influence of international institutions have been yet unsuccessful due to substantial socioeconomic inequality, political instability, and institutional culture and management based on Weberian principles. It is emphasized that the key obstacle to reforms is that the need for administrative changes is not rooted in the minds of administrators and managers. The values of the ‘government effectiveness’ indicator for Brazil and Ukraine are compared. A gradual positive dynamics of Ukrainian government’s activity (as distinct from that of the Brazilian government) is noted, which is assumed to be due to cooperation with society and the implementation of European values and standards of Good Governance. The focus is laid on the possibility of applying a mixed, hybrid approach to improving governance efficiency in developing countries. Its reference point is a competent government, the effectiveness of which is enhanced by the use of information technologies of new generation (artificial intelligence, etc.), and issues of transparency and accountability are measured by the public using established parameters. It is proposed to expand the knowledge about the concept of ‘Intelligent Governance’ with the provision about the professional intelligence of officials as a lever for increasing government efficiency. It has been concluded that to ensure the effectiveness of the government in developing countries, it is important to focus on the cooperation between the authorities and the public for their general mutual benefit.
Recommendations for implementing distributed ledger technology (blockchain) in the public sector of Ukraine based on global experience
Authors: Basiuk Oleksandr
Published: December 2023

Integrating new technologies such as distributed ledger technology into government systems is a multifaceted process characterized by numerous potential benefits, associated costs, and risks. Previous and existing pilot implementations of blockchain-based software solutions in the public sector have demonstrated that this technology can have varying impacts depending on contextual factors, including the specific type of chosen government service. Furthermore, within each distinct area of public services, the implementation of e-governance technologies can yield different outcomes for various stakeholders, including government entities, public servants, and citizens.

Therefore, this article provides a review and analysis of global experiences with the utilization of distributed ledger technology in various domains of the public sector. To achieve this, several countries with advanced expertise in e-governance and the implementation of distributed ledger technology-based solutions were identified. Drawing from the experiences of these nations and considering the unique features, advantages, maturity level of blockchain technology, and existing solutions based on it, general recommendations were formulated regarding the implementation of distributed ledger technology (blockchain) in Ukraine’s public sector.
A phenomenon of environmental security: categorical and conceptual approaches in the context of public governance
Authors: Radchenko Oksana
Published: December 2023

The article analyzes the phenomenon of environmental safety as one of the most important issues of today’s reality, which reflects the impact of human activity in various fields on the surrounding natural environment, which is an acute and urgent problem of our time, which actualizes the need for scientific understanding of the phenomena and processes of both global environmental changes and direct human influence on the state of the environment in the context of public management and regulation of the processes of ensuring the environmental security of national states and the entire world community.

The purpose of the research is to elaborate and systematize scientific categories, concepts and definitions of the sphere of public management and administration, related to the issues of ensuring environmental safety.

Due to the wide scientific attention and the intensity of the disclosure of the problems of the phenomenon of ecological safety in the scientific discourse, there is an inevitable conflict in the interpretation and understanding of certain scientific categories and definitions of a logical chain of concepts related to the root concept, which in this case is ecological safety. A certain solution to this scientific contradiction is the disclosure of the interrelationship of the main definitions of the categorical-conceptual apparatus of public administration in the context of scientific attention to two interdependent and at the same time relatively independent branches of the root concept of “environmental safety”, where the first considers the safety of a person and his life activities, proposed in this article. and the second is security in the state dimension.

Some academic discourse on environmental security issues demonstrates different approaches and visions of related categories and concepts, but is unified in the understanding that in the modern philosophy of public management, the cornerstone of effective management should be sustainable development based on caring for nature, reducing the anthropological burden on the noosphere, rational use of natural resources with a gradual transition from hydrocarbon energy to renewable, balanced human interaction with the living environment for future generations.
DISEÑO DE UN RECORRIDO DE ESTUDIO E INVESTIGACIÓN QUE COMBINA FOTOGRAFÍA, GEOGEBRA y FUNCIONES MATEMÁTICAS
Authors: Rizzo Karina Amalia , Costa Viviana Angélica
Published: December 2023

En este trabajo se presenta el diseño, la planificación y una breve descripción de la implementación piloto de la propuesta de un Recorrido de Estudio e Investigación, en el marco de la Teoría Antropológica de lo Didáctico. Esto es parte de una investigación más amplia, de la que se comparten sus objetivos, las preguntas de investigación y, cómo se llevaría a cabo. El Recorrido de Estudio e Investigación que parte de la pregunta generatriz: ¿Cómo resolver una situación problemática real utilizando una fotografía, GeoGebra y funciones matemáticas? para ser implementado en un curso de matemática en la escuela secundaria argentina con jóvenes de entre 15 y 16 años. Su diseño se basa en un concurso internacional, que se realiza periódicamente cada año desde 2016, denominado FotoGebra, libre, gratuito y abierto para, jóvenes de entre 13 a 17 años y profesores en formación.
Generational Dynamics of Innovation Adoption in Chinese Consumer Markets: A Comprehensive Analysis
Authors: Wang Li
Published: December 2023

This extensive and comprehensive study delves into the intricate dynamics of generational responses to innovative marketing strategies within the dynamic landscape of the Chinese consumer market. Given China’s rapid economic growth and technological advancements, it has become imperative for businesses and marketers to grasp how different generations engage with marketing innovations. This study encompasses Baby Boomers, Generation X, Millennials, and Generation Z, each shaped by unique life experiences and societal contexts, resulting in distinct preferences and behaviors. Furthermore, the study offers a thorough analysis of how diverse generations in China interact with and respond to innovative marketing strategies, providing academic researchers and businesses operating in the rapidly evolving Chinese consumer marketing landscape with actionable insights. Understanding these generational dynamics is crucial for developing marketing strategies that resonate with diverse generational segments and harnessing the power of technology to connect with consumers across all age groups. The dynamic landscape is further enriched by the proliferation of digital technologies, social media platforms, and e-commerce ecosystems. This study scrutinizes how these generational cohorts interact with innovation in marketing, considering preferences, technological adoption patterns, cultural influences, and attitudes toward trust and privacy. Additionally, it examines generational disparities in marketing channel preferences, offering valuable insights for companies aiming to tailor their marketing strategies to effectively engage diverse generational segments in China. Importantly, this research underscores the strategic significance of understanding generational differences in marketing innovation adoption. It emphasizes that this knowledge is not solely an academic pursuit but rather a critical necessity for companies seeking to thrive in one of the most competitive consumer markets globally. By acknowledging and responding to the distinct preferences and behaviors of various generational cohorts, businesses can forge meaningful connections, optimize return on investment, and adeptly navigate the evolving consumer landscape.
RISK FACTORS FOR OBESITY AND METABOLIC SYNDROME IN ADOLESCENTS
Authors: N.G. Larina , O.V. Azovtseva
Published: December 2023

Obesity is one of the urgent problems of the healthcare system. Despite a large number of studies, the issue of risk factors for this condition, as well as the associated metabolic syndrome, remains relevant to date. Also interesting is the question of analyzing risk factors in patients with obesity and metabolic syndrome, and without them. The purpose of the study was to study risk factors in adolescents with obesity and metabolic syndrome. The study examines the role of perinatal factors, heredity, peculiarities of eating behavior, the role of psychological status and microsocia. It was shown that perinatal factors (complicated course of pregnancy and childbirth), problems of early breast-feeding (previously artificial feeding, perinatal damage of the central nervous system, anemia, rickets), as well as burdened heredity for cardiovascular and endocrine pathology (obesity, diabetes mellitus 1 type) had all obese adolescents, regardless of the presence of metabolic syndrome; the peculiarities of the nutritional status (food with a lot of carbohydrates and refined fats, protein deficiency) in combination with physical inactivity and the formation of an unhealthy lifestyle were noted in all examined adolescents. Psychological problems, such as a high level of anxiety, low self-esteem, social phobia, violation of personal perception and motivation, as well as pathology of the microsocial environment, that is, family problems prevailed in adolescents with obesity and components of metabolic syndrome. The identified features should be taken into account when developing prevention and rehabilitation programs for overweight and obese patients.
DISCOVERY OF AN ORIGINAL MODEL TO STUDY THE INFLUENCE OF PHARMACOLOGICALLY ACTIVE SUBSTANCES ON THE RATE OF OXYGEN CONSUMPTION IN THE PROSTATE TISSUE
Authors: A.O. Lobkarev
Published: December 2023

The article provides a review of foreign scientific literature on existing approaches in scientists' ideas about the quantum theory of brain physics and the theory of quantum-like consciousness. It is shown that in recent years, physics and psychology have made important scientific advances; the emergence of new tools has led to the development of neuroscience, which makes it possible to study the state of the brain when known mental functions are preserved or impaired. The use of mathematical methods has made it possible to develop computational models that describe the fundamental functions of the brain and implement them in technological applications. The most pressing issues of modern research in the field of mental processes of the brain, such as perception, cognition, emotions, consciousness and learning, researchers call the problems of the universal properties of human behavior in various conditions and cultures; the potential of computational psychiatry to predict, understand and treat mental disorders; neural mechanisms of influence on mental content at higher levels of organization of the hierarchical brain; mechanisms of the emergence of abstract ideas from sensorimotor accidents, etc. Currently, in understanding the cognitive processes of the brain, perception, understanding, cognition, mental lexicon, understanding the generation and nature of emotions, memory, learning, etc. A number of researchers use the theory of quantum or quantum-like consciousness. Research in this area is both empirical and theoretical in nature, with the postulates of the theory being considered mainly related to quantum physics due to the lack of other areas in which quantum-like properties are supposedly manifested. It is believed that despite modern advances in artificial intelligence models, neural networks cannot reach the level of the human brain, partly due to differences in the way information is encoded and processed. In order to develop the potential of brain-based artificial intelligence, quantum neural networks are proposed that are similar to the mechanisms and phenomena in the brain. Interactions between biologically important molecules in the brain may underlie the quantum metalanguage that governs the behavior of humans and animals.
SEARCH FOR MOLECULAR TARGETS OF A NOVEL 9-DIHYDROACRIDONE COMPOUND
Authors: A.A. Bagdosaryan , E.A. Kutorkina , V.A. Pakina , E.V. Bogoslovskaya , D.S. Blinov , M.V. Tolstov , E.V. Semeleva , E.V. Blinova
Published: December 2023

In this work, the molecular targets of a new compound with antitumor effect, a 9-dihydroacridone derivative, were determined. The study was carried out in a virtual software environment for receptor-oriented flexible docking Autodock 4.2. The ligands were prepared using the MGL Tools 1.5.6. Ligand optimization was performed using the Avogadro software. The crystallographic structures of the active site macromolecules of human folate receptors (FOLR2) and colony stimulating factor kinase 1 (CSF1R) from the Protein Data Bank (PDB ID: 4KN2 and 4R7I, respectively) were used. A new compound, 9-aminium-3,3-dimethyl-3,4-dihydroacridin-1(2Н)-one L-2-hydroxybutanediovatate (laboratory name LHT-17-19), was studied. LHT-17-19 formed a stable complex with the type III receptor of tyrosine kinase of the monocyte and macrophage colony-stimulating factor (CSF1R) and with the folate receptor FOLR2 with Affinity DG -10.2 kcal/M, EDoc -6.82 kcal/M, Ki 9.99 uM and 10.0 kcal/ M, Edoc -7.05 kcal/M, Ki 6.85 uM, respectively. In terms of the main indicators of affinity LHT-17-19 was not inferior to the reference drugs imatinib and pemetrexed. Receptor kinases CSF1R and FOLR2 can be considered as potential molecular targets for novel medication candidate 9-aminium-3,3-dimethyl-3,4-dihydroacridin-1(2H)-one L-2-hydroxybutanediovate.
ASSESSMENT OF THE PREVALENCE AND STRUCTURE OF CHRONIC KIDNEY DISEASE IN DIABETES
Authors: A.A. Ulanova , M.V. Esina , E.I. Yamashkina
Published: December 2023

The incidence of diabetes mellitus has more than doubled over the past ten years. The prevalence of chronic kidney disease is comparable to the prevalence of diabetes mellitus. Chronic kidney disease occurs in diabetes mellitus in 20-40% of cases. The aim of the study was to analyze the prevalence and structure of chronic kidney disease in diabetes mellitus according to the diabetes registry «Polyclinic № 4», Saransk. According to the diabetes registry data, the structure and prevalence of chronic kidney disease in patients with type 1 and type 2 diabetes mellitus, anthropometric indicators, the duration of diabetes mellitus and chronic kidney disease, and indicators of metabolic control of diabetes were analyzed. In the present study, the prevalence of chronic kidney disease was 17% in type 1 diabetes mellitus and 19% in type 2 diabetes mellitus. At the same time, in both types of diabetes mellitus, chronic kidney disease of stage C2 (50% in type 1 and 52% in type 2) and C3 stage (39% in type 2 and 28% in type 1) predominated. type of diabetes). Glycosylated hemoglobin was within the target range in 78% of type 1 diabetic patients and in 83% of type 2 diabetic patients. In patients with diabetes mellitus and chronic kidney disease, it is necessary to intensify hypoglycemic therapy, achieving target indicators of carbohydrate metabolism. The only indicator of the lipid spectrum, which is presented in the registry, was total cholesterol, it is necessary to study the full lipid spectrum.
EVALUATION OF THE IMMUNOMODULATORY ACTIVITY OF THE DRY EXTRACT OF THE HERB OF HELIANTHUS TUBEROSUM L.
Authors: I.V. Mikhailova , Y.V. Filippova , A.I. Smolyagin , A.A. Sinegovets , O.L. Saybel , V.N. Dul , T.D. Dargaeva
Published: December 2023

. The purpose of the study was to evaluate the immunomodulatory properties of the dry extract of Jerusalem artichoke herb in terms of weight (thymus, spleen), number of cells (thymus, spleen, bone marrow) of the immune system organs, indicators of cellular and humoral immunity in mice on a model of experimental immunodeficiency induced by the cytostatic methotrexate.
Materials and methods. The study of the immunomodulatory activity of the dry extract of Jerusalem artichoke herb was evaluated by the ability to restore the mass (thymus, spleen), the number of cells (thymus, spleen, bone marrow) of the immune system organs, indicators of cellular, humoral immunity and phagocytic activity of peritoneal macrophages of outbred mice under conditions of immunosuppression induced by methotrexate, to the level of intact mice, in vivo.
Results. Analysis of the effect of the dry extract of Jerusalem artichoke herb in in vivo systems found that the dry extract of the herb Helianthus tuberosum L. had no effect on the mass (thymus, spleen) and the number of cells (thymus, spleen, bone marrow) of the immune system organs, the severity of the delayed-type hypersensitivity reaction, antibody production, phagocytic activity of peritoneal macrophages of intact mice and restored these parameters of the immune system in animals treated with the cytostatic methotrexate to the level of intact animals, which was comparable to the effect of the reference drug "Immunal".
Conclusion. The dry extract of Jerusalem artichoke herb can be considered as a promising agent that restores the parameters of cellular, humoral immunity, the phagocytic activity of peritoneal macrophages and the cellular composition of the immune system under conditions of immunosuppression induced by methotrexate, to the level of intact animals, the effectiveness of which is comparable to the effect of the comparator drug "Immunal