bluuebunny/crossref_metadata_2025 huggingface dataset:
Situación actual de la prevención en la diabetes mellitus tipo 2
Authors: Garmendia Lorena Fausto Aníbal
Published: May 2022

Se revisan los aspectos de la diabetes mellitus tipo 2 (DM2) que pueden ser motivo de prevención,y permitan una disminución de la prevalencia y morbimortalidad por esta enfermedad en elmomento actual. Estudio descriptivo, transversal, en el que se revisan los aspectos y métodosque previenen tanto el desarrollo de esta enfermedad, así como de sus manifestaciones crónicas,complicaciones agudas y morbilidades conexas. Se concluye que existen medidas preventivasque facilitan la disminución de la prevalencia y morbimortalidad de las personas con diabetesmellitus tipo 2.
Relación entre el tipo de fisura labiopalatina y la disfunción de la trompa de Eustaquio en niños, Perú 2020
Authors: Antayhua Ortiz Sara Isabel
Published: May 2022

Objetivo: Determinar si el tipo de fisura labiopalatina está asociada a mayor riesgo de alteración de la trompa de Eustaquio. Materiales y métodos:  Se realizó un estudio observacional retrospectivo no experimental de los niños operados de fisura labiopalatina en el Hospital San Bartolomé durante el 2018 y 2019. Resultados: Se evaluó a un total de 48 pacientes a quienes se les realizó timpanometría previa a la cirugía de fisura palatina, encontrándose 62,5% varones (n=30) y 37,5% mujeres (n=18) y la media de edad fue de 1,3 años, para determinar el tipo de fisura labiopalatina se usó la clasificación de Veau, el tipo más frecuente hallado fue Veau tipo III, con 62,5% (n=30), siendo la menos frecuente Veau tipo I con 4,2% (n=2). La evaluación de la función de la trompa de Eustaquio se realizó mediante timpanometría definiéndose como patológica la curva tipo B, en el grupo de estudio se encontró una prevalencia global de curvas tipo B de 66,7% (n= 32), mientras que las curvas A y C, tuvieron 33,3% (n=16). Mediante la distribución binomial se determinó un valor fue de 0,4095 o 41%. La probabilidad que el diagnostico Veau IV tenga curvas tipo B de forma más frecuentes que las otros tipos, mediante la prueba Binomial fue significativo. (p=0,000038<0,05). Conclusiones: El tipo de fisura palatina mayormente asociado con alteración de la función del oído medio, expresado mediante curvas de timpanometría tipo B, es la fisura tipo IV según clasificación de Veau, esta relación es estadísticamente significativa.
Características clínicas y epidemiológicas de la estenosis hipertrófica de píloro en un hospital de lima Perú.
Authors: Torres Guinand Carlos Guillermo , Reque García Armando
Published: May 2022

Objetivo: Determinar las características clínicas y epidemiológicas de la estenosis hipertrófica de píloro en un hospital de lima Perú. Materiales y métodos: Se realizo un estudio descriptivo, retrospectivo correspondiente de los años 2013 al 2019, en el servicio de cirugía pediátrica del hospital docente madre niño “San Bartolomé”. En donde recolectamos los datos a través de las historias clínicas con diagnóstico estenosis hipertrófica de píloro. Resultados: Se obtuvieron un total de 59 pacientes, de los cuales 79.7% fueron varones, 68.4% primogénitos, con una media de edad de 31.3 +/- 13.6 días de nacido. 100% presento vómitos, 44.1% reptaciones y solo 35.6% presento oliva pilórica palpable. Tiempo quirúrgico promedio 51.39 +/- 19.1 minutos, estancia hospitalaria promedio de 6.35 +/- 6.56 días, se presentó complicaciones en un 13.6% y una mortalidad de 3.4%. Conclusiones: La importancia del inicio precoz de la vía oral, así como el manejo postquirúrgico es importante en estos pacientes para poder disminuir su estancia hospitalaria, se debe de tomar en cuenta el manejo del paciente postquirúrgico y sus complicaciones respiratorias.
Presencia de Escherichia coli en la playa Pucusana, Lima, y su potencial efecto en la salud pública
Authors: Huayanay Quevedo Cinthia Milagros , Aldoradin Basilio Veronica , Guerra Santa Cruz Alcides
Published: May 2022

Objetivo: Determinar los valores de la bacteria e indicador fecal Escherichia coli  para aguas de mar de uso seguro y recreacional de la playa Pucusana, Lima. Materiales y Métodos: Las campañas de muestreos se realizaron una vez por semana en el estío del 2019 y procesados en el Laboratorio de Microbiología de la FCB de la Universidad Ricardo Palma mediante colimetría y el método del número más probable NMP. Resultados: Se comprobó la presencia de esta especie en todas las muestras analizadas, con el valor crítico de 3000 NMP/100 ml. Diez cepas fueron enviadas al INS que determinó que no existe ningún serotipo patogénico, y de acuerdo con regulación peruana la calificación es inaceptable. Conclusiones: Se demuestra la carencia de salubridad ambiental y su relevancia en salud pública porque la disentería puede ser generada por este coliforme que afecta al crecimiento y desarrollo infantil e impacta en los adultos. Los factores de riesgo son producidos principalmente por la producción y vertido de las aguas residuales llevados por los colectores al mar y aunque importante proporción de estas aguas son procesadas en la Planta de Tratamiento de Aguas Residuales PTAR Pucusana que son reutilizadas en riego de áreas verdes y así poder integrar también su reúso en agricultura, se identificaron vertimientos domésticos y municipales que descargan al Pacífico, problemática que debe tener un buen manejo y fiscalización ambiental porque deteriora el medio ambiente sobre todo los mares y nuestras vidas dependen directamente de los océanos.
Kajian Mutu Ikan Layang (Decapterus sp) di Pasar Tradisional Girian Kota Bitung
Authors: Sinurat Buhit Arjuna Febrianto , Mongi Eunike L , Dotulong Verly , Dien Henny Adeleida , Reo Albert R , Mentang Feny
Published: May 2022

Fish in a fresh state has good quality so the selling value is high, conversely if the fish is less freshhas a low quality so the price is low. Freshness in fish has a very important role in determining thequality of fishery products. The freshness of the fish cannot be improved but maintained so thatproper handling is needed so that the fish can reach the hands of consumers or processing plantsin a fresh state. One way to maintain the freshness of fish is to apply cold chains through theprovision of ice, in addition to the application of sanitation is also important. The aim of the studywas to analyze the quality of fresh kite fish(Deacpterus sp.) sold to eight different sellers in thetraditional Girian market of Bitung City, which will be taken in the morning. The parametrsanalyzed were TPC(Total Plate Count),moisture content, pH, and organoleptics. The data obtainedis analyzed descriptively. Overall, the best fish quality is obtained in trader H. But in all theparameters obtained still have a quality that is worth consuming.
Mutu Makaroni Tuna Saus Karbonara
Authors: Daud Mega Dita , Kaparang Josefa T , Wonggo Djuhria , Damongilala Lena , Palenewen Joyce , Makapedua Daisy M , Reo Albert
Published: May 2022

The Covid-19 pandemic period is faced with the adaptation of new habits, namely the community in himbau to maintain health and improve immunity to avoid exposure to covid-19. One of them is by consuming fish meat that has good nutritional value for the body, the high protein and omega-3 in fish meat makes fish an excellent intake consumed during the covid-19 pandemic. The purpose of this study is to find out the quality of the divesifikas products of tuna karbonara divesifikas. with water content parameters, pH knows the level of fondness of carbonic tuna with organoleptic tests and Total Plate Number.
PROFIL ASAM AMINO KECAP IKAN TONGKOL (Euthynnus affinis) YANG DIFERMENTASI DENGAN PENAMBAHAN NENAS
Authors: Angela Gabriella Caristy , Mentang Fenny , Onibala Hens , Montolalu Roike , Sumilat Deiske , Luasunaung Alfret
Published: May 2022

Kecap ikan adalah salah satu produk hasil fermentasi dengan bahan baku ikan. Ikan yang digunakan dalam penelitian ini adalah ikan tongkol ( Euthynnus Affinis C. ) yang merupakan hasil tertinggi komoditi perikanan di Sulawesi Utara yang memiliki kandungan protein, asam lemak omega-3, vitamin dan mineral yang tinggi dan juga sangat kaya gizi. Penelitian ini bertujuan untuk mendapatkan konsentrasi terbaik dari buah nenas yang ditambahkan dan meningkatkan pengaruh konsentrasi buah nenas terhadap lama fermentasi dan profil asam amino. Penelitian menggunakan penambahan sari buah nanas dengan konsentrasi (0%, 10%, 15% dan 20%) dan garam 10% dengan lama penyimpanan selama 10 hari dalam inkubator.Variabel yang diamati dalam penelitian ini adalah Asam Amino, Kadar Protein, Kadar Karbohidrat, Kadar Lemak, Kadar Nitrogen, Kadar Abu, Kadar Air, dan pH. Hasil penelitian menunjukkan bahwa sampel kecap ikan sari buah nanas 15% dengan garam 10% dapat mempercepat proses hidrolisis pada hari ke-10. Dari mutu kimiawi, hasil laporan asam amino LC / MS didapatkan 9 kandungan utama yang ada pada kecap ikan tongkol 15% yaitu: L-Leucine, L-Valine, L-Tryosine, L-Cystine, AABA, L-Alanine, L-Glutamic Asam, Glisin, dan L-Serin.Hasil analisis kandungan proksimat (kadar air 61,3%, kadar abu 9,22%, kadar lemak 1,52%, kadar protein 3,98%, kadar karbohidrat 3,11%) pada kecap ikan tongkol 15% masih dalam standar mutu kecap ikan yang baik, dan kandungan nitrogen kecap ikan tongkol 15% dapat memenuhi Standar Industri Thailand Grade 1.
Pengujian TPC, Kadar Air dan pH pada Ikan Tongkol (Euthynnus Affinis) Asap Cair Yang Disimpan Pada Suhu Ruang
Authors: Upet Emanuel , Salindeho Netty , Reo Albert R , Montolalu Lita , Kaparang Josefa T , Makapedua Daisy M , Dotulong Verly
Published: May 2022

Mackarel Tuna fish (Euthynnus affinis) is a leading commodity as a source of food for people in North Sulawesi. The purpose of this study was to process mackarel tuna (Euthynnus affinis) using liquid smoke stored at room temperature and then tested the product quality, namely) water content, total plate count (TPC), and pH value. The results of the research the resulting moisture content ranged from 35.7 to 58.3%, according to the Indonesian National Standard (SNI) 2725: 2013 that the maximum water content of smoked fish with the maximum heat smoking method was 60%, the total plate count (TPC) was around The average total plate number of smoked fish produced is 0.52 x 10-4 to 2.83 x 10-5 cabbage / g, this value shows in accordance with SNI 2725: 2013 that the total plate number of smoked fish with the maximum heat smoking method is 5 x 104 kol / g, while the average pH value is 5.64, this value shows the pH of smoked fish is below neutral pH, so it can be concluded that the smoked fish contains acid. It is concluded that this research has fully met the requirements for public consumption so that it can be produced as a fishery product.
AKTIVITAS ANTIKANKER SERVIKS RUMPUT LAUT Sargassum sp
Authors: Tinanggal Perlina , Sanger Grace , Pandey Engel Victor , Makapedua Daisy Monica
Published: May 2022

Kanker merupakan kondisi patologis yang menjadi salah satu utama penyebab kematian didunia. Selama beberapa dekade terakhir, langkah luar biasa telah dibuat untuk mengurangi insiden dan kematian kanker serviks dengan penerapan berbagai strategi pencegahan dan pengobatan. Tujuan penulisan artikel ilmiah untuk menemukan senyawa antikanker baru, yang sangat penting untuk pengobatan kanker dari rumput laut, karena rumput laut adalah salah satu produk laut sumber terbesar metabolit kimia aktif. Penelusuran literature menggunakan kata kunci, Sargassum sp, kanker serviks, HPV, obat antikanker serviks. Metode pengumpulan literature mengunakan elelectronic data base: PubMed, Web of Science, Science Direct, Elsevier, Springer Google and Google Scholar. Hasil yang diperoleh:, mekanisme senyawa antikanker melawan virus, aktifitas sitotoksik  rumput laut melawan sel HeLa dan bebetapa jenis obat antikanker. Dapat disimpulkan bahwa Sargassum sp. mempunyai aktifitas sitotoksik melawan sel HeLa, sehingga dapat dijadikan sumber obat antikanker serviks. Rumput laut Sargassum sp. yang tumbuh melimpah di Indonesia  dapat digunakan didalam pengobatan untuk menurunkan tingkat kasus dan kematian akibat kanker.
Kajian Mutu Ikan Layang (Decapterus russelli) yang Direndam dalam Asap Cair Sabut Kelapa dan Disimpan pada Suhu Ruang
Authors: Sarundayang Ratniarti , Salindeho Netty , Montolalu Lita , Pongoh Jenki , Montolalu Roike Iwan , Makapedua Daisy Monica
Published: May 2022

Provinsi Sulawesi Utara, memiliki beberapa potensi perikanan pelagis yang dapat menunjang perekonomian masyarakat perikanan, salah satu komoditas perikanan pelagis yang berpotensi yaitu ikan layang (Decapterus russelli), Ikan merupakan bahan pangan yang mudah rusak karena mengandung protein dan air yang cukup tinggi. Oleh karena itu ikan harus segera diolah untuk mencegah terjadinya kemunduran mutu. Salah satu cara untuk mencegah terjadinya kerusakan pada ikan harus dilakukan pengawetan, teknik pengasapan ikan. Pengasapan merupakan salah satu cara pengolahan pangan yang telah lama dikenal sebagai salah satu tahapan dalam pengolahan produk pangan. Tujuan dari pengasapan ialah menghambat laju kerusakan produk, namun dalam perkembangan juga ditunjukan untuk memperoleh  kenampakan  tertentu pada produk asapan dan cita rasa asap pada bahan makanan. Penelitian ini bertujuan untuk mengetahui proses kemunduran mutu produk ikan layang asap cair selama perendaman  dan  lama  penyimpanan suhu ruang berdasarkan nilai Ph, kadar air dan cemaran mikroba dengan menghitung nilai angka lempeng total (ALT), data yang diperoleh dari hasil penelitian yang dilakukan dihitung nilai rata-ratanya, lalu dilanjutkan dengan  uji ANOVA pada aplikasi SPSS. Hasil analisa ikan layang asap cair diperoleh nilai angka lempeng total 1.8 x 107 – 1.6 x 1010, kadar air 39.5% – 62.7%, dan stabilitas pH 5.78 – 7.1
Model Pembelajaran Menyimak Bahasa Indonesia Tipe Hilwah Natiqah Dalam Pengembangan Karakter Mandiri Siswa Sekolah Dasar
Authors: Majdi Muhammad , Hafidzaturrahmi Hafidzaturrahmi , Naziah Bahjatun
Published: May 2022

Karakter Mandiri menjadi salah satu pondasi bagi peserta didik dalam bekalnya menjadi manusia yang tangguh dan unggul. Hal tersebut menjadi latar belakang penelitian ini yang berkolaborasi dengan pembelajaran menyimak pada materi Bahasa Indonesia SD/MI, kegiatan mendengarkan pada jenjang sekolah dasar dengan maksud menumbuhkan jiwa mandirinya dengan beberapa indikator seperti kemampuan dalam menentukan nasib sendiri, kreatif dan inisiatif, mampu mengatur tingkah laku, bertanggung jawab, mampu menahan diri, membuat keputusan-keputusan sendiri mampu mengatasi masalah tanpa ada pengaruh dari orang lain. Metode penelitian kualitatif deskriptif dengan pendekatan induktif. Subjek penelitian adalah siswa kelas 5 SD di Desa Keramat Kec. Haur Gading Kab. Hulu Sungai Utara dengan jumlah siswa sebanyak 7 orang yang terdiri dari 3 orang laki-laki dan 4 orang perempuan. Objek adalah model pembelajaran menyimak dalam mata pelajaran Bahasa Indonesia dengan strategi Hilwah Natiqah dalam pengembangan karakter mandiri. Hasil penelitian implementasi strategi Hilwah Natiqah berjalan dengan baik sesuai langkah-langkahnya yang terdiri dari bagian 1) persiapan, 2) pelaksanaan seperti membentuk baris setengah lingkaran, memutar musik, pemilihan siswa yang menjawab, siswa lain menyimak, dan disampaikan. Sedangkan korelasi pendidikan karakter mandiri dengan strategi Hilwah Natiqah terdapat pada beberapa langkah penerapan strategi pembelajaran sesuai dengan indikator pendidikan karakter religius, seperti sikap dan perilaku yang tidak mudah tergantung pada orang lain dalam menyelesaikan tugas-tugas.
A DELAYED PRESENTATION OF POSTERIOR HYPOPITUITARISM FOLLOWING TRAUMATIC BRAIN INJURY – A CASE REPORT OF A 24 YEAR OLD ASIAN FEMALE.
Authors: Balaji Akshay , Damodharan Suresh , Prasad Ganesh
Published: May 2022

Background: Cases of post traumatic hypopituitarism are rarely contemplated in the Indian
subcontinent. However global literatures disclose that the incidence rate of hypopituitarism following
traumatic brain injury is around 15-30%. Most hospitals do not routinely screen patients for pituitary dysfunction following
traumatic brain injury due to the lack of proper protocol supporting the same. Hence large number of cases with varying
pituitary abnormalities is procrastinated, which could have been otherwise beneted from early interventions. This case is a
classic example of delayed exhibition of posterior hypopituitarism post traumatic brain injury, which has signicantly
compromised the quality of life of the patient in later stage due to the failure of timely screening.
Case Presentation:This is a case of 24 year old female who sustained a traumatic brain injury 3 years ago allegedly due to
domestic abuse. The patient presented to the urology department with the complaints of polyuria, polydipsia, secondary
amenorrhea, sleep disturbance and weight gain for 6-7 months. The patient was not under regular follow-up for the traumatic
injury. On further evaluation, all the anterior pituitary hormones were found to be normal. We further investigated the case with
biochemical investigations and an MRI of brain (plain and contrast) which showed a thickened enhancing pituitary stalk with
absence of posterior pituitary bright spot with a normal anterior pituitary gland – suggestive of Central Diabetes Insipidus.
Upon initiation with Desmopressin, the patient showed signicant symptomatic improvement.
Conclusion:One of the most common complications of traumatic brain injury is hypopituitarism. Early screening for
hypopituitarism in such cases will help us intervene early and improve the quality of life of the patients.
MANAGEMENT OF LEFT PARADUODENAL HERNIA - A CASE REPORT
Authors: Santhi B. , Dorai D. , Gunasekaran B. , Yuvarani P.
Published: May 2022

Paraduodenal hernias are rare type of internal hernias also known as Treitz hernia or Mesocolic hernia
that occur due to congenital anomaly in rotation of the midgut. The anomaly is either malrotation of
midgut or failure of mesentery of ascending colon to fuse with parietal peritoneum. The presenting symptoms can range from
mild abdomen pain to small bowel obstruction and gangrene. The hernias can be left or right sided depending upon their
relationship with the mesenteric vessels of small bowel.
Internal hernias, including paraduodenal hernia (the most common), periceacal, foramen of Winslow and inter sigmoid
hernias, account for approximately 0.5 to 5.8% of all cases of intestinal obstruction and are associated with high mortality rate.
We present a case of left paraduodenal hernia occurring in 40yr old male patient who presented with complaints of mass and
pain in left side of abdomen for 1 week. CT imaging was done which showed clusters of dilated bowel segments with displaced
mesenteric vessels at hernial orice. After evaluation diagnosed as left paraduodenal hernia and through laparoscopy bowel
loops decompressed from the fossa of Landzert and hernial sac repair done. Post operative period was uneventful and was
discharged after 3 days.
Paraduodenal hernias are rare causes of small bowel obstruction which can be difcult to diagnose clinically and require cross
sectional imaging for diagnosis. These hernias occur due to congenital anomaly of malrotation of the small bowel and fusion of
mesentery. Surgical correction is done electively or on emergent basis with open or laparoscopic technique depending upon
the clinical scenario and availability of laparoscopy
RETROSPECTIVE ANALYSIS OF COVID-19 POSITIVE PARTURIENTS POSTED FOR CAESAREAN SECTION IN TERTIARY CARE CENTRE
Authors: M. Tambey Ranjeeta. , D. Agrawal Mitali. , A. Bakshi Sandhya. , G. Tirpude Naresh.
Published: May 2022

Background And Aims: Parturients posted for LSCS present with physiological changes due to
pregnancy and gravid uterus, may have associated co-morbidities, superadded by COVID 19 infection
poses a real challenge for an anesthesiologist. Urgency in obstetric anesthesia and extreme precautions needed to avoid this
contagious disease further increase the burden on the anesthesiologist. This study focuses on perioperative presentation,
management, and outcome of patients in a tertiary level hospital.
Method: 329 pregnant females with RAT or RTPCR positive for COVID 19 and undergoing cesarean section from 1st May 2020
to 31st July 2021 were included in this retrospective observational study. Data was collected and analyzed from OT, ICU, WARD
records, patient medical and electronic records, and maternal mortality data.
Results: Amongst 329 parturients, 98.48%(324/329) received spinal anesthesia, one received epidural anesthesia (0.30%)
and 1.21%(4/329) required general anesthesia. The incidence of hypotension was 5.77% (19/329), managed with inj.
Mephentermine without inotropes. The intraoperative course was uneventful except for one case of CRA, revived successfully.
Nine patients (2.73%) required ICU care. Oxygen support by either nasal prongs or face masks was given to 3.95% (13/329)
patients. Three patients (0.91%) required NIV support and three patients (0.91%) required invasive ventilation postoperatively.
The overall mortality was 0.61% (2/329). The mean duration of hospital stay was found to be 8.2 ± 5.03 days
Conclusion: Neuraxial anesthesia remains a technique of choice for LSCS and can be safely employed in the parturients
even with moderate pneumonia. General anesthesia can be reserved for patients of severe covid pneumonia.
FOREIGN BODY EAR AND NOSE IN PATIENTS ATTENDING A TERTIARY CARE HOSPITAL-OUR TWO YEAR EXPERIENCE.
Authors: Majeed Dar Younus , Bashir Seerat , Ali Ihsan
Published: May 2022

Background: Foreign bodies (FBs) in the ear and nose are relatively frequent emergencies seen in the
ENT emergency and OPD. The FBs in the ear and nose are more common but not limited to children and
mentally challenged adults. The most common ear and nose foreign bodies include plastic toys, food, and small household
items. Majority of FBs are harmless but few like insects and sharp objects are extremely uncomfortable requiring emergency
removal.
Aims: and Objectives: In the current study we aimed to evaluate the common types, prevalence, age of presentation, sex
predilection, clinical presentations, treatment approaches used and complications during extraction of ear and nose FBs in
patients presenting FB induced emergency.
Methods: The current study was a prospective study carried out for 2 years (June 2019-June 21). All the subjects attending Sri
Maharaja Hari Singh Hospital (SMHS), Government Medical College Srinagar (J&K) presenting ear and nose FBs induced
emergency, were enrolled in the current study. All the relevant demographic, clinical, and therapeutic modalities of each
patient were recorded and then analysed using statistical software (SPSS version 14.)
Results: A total of 770 subjects were recruited in the study with nearly equal males and female representation. The majority of
cases (~70%) were in the age group of <10 years in both the genders. Majority of the cases were from urban areas. Among all
the subjects recruited, a greater number of subjects had FB in ear (~63%), while as 37% had FB in the nose. About 5% of the
subjects reported FB bilaterally in the ears. Paper was the prevalent nose FB, while as bead was found pervasive in the ear. Only
4.5% subjects needed general anaesthesia for the removal of FB, while as only 10.8% experienced bleeding during the FB
removal.
Conclusion: Foreign body ear and nose pose a common ENT emergency in the clinic and are usually presented in the young
subjects. Unlike, the FB in the nose, the ear FB can be more harmful by causing tympanic membrane perforation. The treatment
modalities for ear and nose FB removal depends upon the type and place of FB impaction in the subject.
REVIEW OF HAEMATOPATHOLOGY IN THE AGE OF ARTIFICIAL INTELLIGENCE-MACHINE LEARNING BETWEEN 2011 AND 2021
Authors: Sedick Qanita , Elyamany Ghaleb
Published: May 2022

Background and Objective: Articial intelligence has transformed pathology diagnostics over the past
decade between January 2011 to December 2021, with new emerging technologies and software
promising to transform and enhance haematopathology diagnostics further. More rapid and procient AI systems appears to
be threatening the role of Haematopathologist in the diagnostic process. This systemic review aims to explore the success of
articial intelligence applications in the eld of haematopathology and assess whether the role of haematopathologist will
indeed prove redundant in the future.
Methods:We performed an extensive search of Pubmed, Medline and National Center for Biotechnology Information (NCBI) at
the U.S. National Library of Medicine (NLM) and google scholar databases for articial intelligence in Haematopathology
between January 2011 and December 2021.Reference lists of articles were thereafter reviewed for additional reviews. The
results are grouped and discussed according to the world health organization grouping of haematopathology disease. Studies
where the AI algorithms were compared to that of specialist pathologist were included as this was the main focus and aim of the
review.
Key content and ndings: Articial intelligent applications on peripheral smears, bone marrow aspirate smears,
immunohistochemical stains are documented sequentially in the manuscript from the introduction of whole slide imaging
applied to peripheral and bone marrow smears for identication of white blood cells to the application of more complex
convoluted neural networks for discrimination of lymphoma and leukaemia subtypes and lymphoma grading. All the studies
documented in this review have shown favourable outcome for articial intelligence applications to haematopathology
disease.
Conclusion: The above studies have demonstrated that articial intelligence can be successfully integrated into
haematopathology diagnostics. Although all studies were shown to be comparable to the pathologist, there is a requirement
for further standardisation and validation studies for optimization of deep learning algorithms. The notion that AI will replace
the pathologist is also incorrect. The microscope will not be replaced. Rather, AI integration into pathology is meant enhance
the accuracy and speed of diagnostic workows enabling the pathologist to focus on more complex laboratory problems. AI
and human pathologists should co- operate, rather than compete.
ROLE OF SERUM ANTIMULLERIAN HORMONE FOR DIAGNOSIS OF POLYCYSTIC OVARIAN SYNDROME IN ADOLESCENCE
Authors: Kanta Das Karuna , Majumdar Manoj Kumar , Sharma Gayatri
Published: May 2022

Polycystic ovarian syndrome is one of the most common endocrinal pathology amongst reproductive
age group females leading to various long term complications in future like infertility , cardiovascular
diseases and diabetes mellitus in future. Thus, an early diagnosis and treatment may be helpful. Serum antimullerian
hormone as is secreted by the primordial follicles will be raised in PCOS females even from adolescence after the development
of HPO axis. Hence , it can be used as a diagnostic marker for PCOS in adolescence.
Materials And Methods : It is a hospital based prospective case control study carried out in Gauhati Medical College and
Hospital from April 2020 to March 2021. 110 adolescent girls between 15 years to 18 years were considered of which 55 fullled
the inclusion criteria and 55 did not after which both the groups were subjected to a set of investigations including S. AMH. The
comparison between two groups with qualitative data were done by chi square test and / or Fischer's test . associated risk
factors were also determined.
Results And Discussion: The serum AMH levels were considerably higher in cases of PCOS which was 11.83+ 3.62ng/ml
compared to controls being 4.14 + 0.98 mg/ml (p<0.05) . Complaints of oligomenorrhoea with increase in BMI, signs of
hirsutism and increase in LH and testosterone levels were found to be more common amongst the cases.
Conclusion: In the study on Serum AMH level showed a statistically signicant rise in cases when compared to controls. It was
noted that there was a rise in LH and total testosterone levels. So, it can be said that S.AMH does have a role for diagnosis of
PCOS in adolescence.
A RARE CASE OF BILATERAL SLIDING INGUINAL HERNIA – A CASE REPORT
Authors: Santhi B. , Dorai D. , Gunasekaran B. , Ahamed Z. Thanveer
Published: May 2022

The purpose of this paper is to present an unusual case of Large Bilateral sliding Inguino-scrotal Hernia.
Sliding inguinal hernias are often unexpected intraoperative ndings, and repair of which can be
technically difcult. A sliding hernia is one where in the posterior wall of the sac is formed by the Bowel. Bilateral sliding hernia
constitute less than 1% of all hernias. We report of a 61 year old male patient who was having bilateral inguino-scrotal swelling
for more than 3 years and its management
EFFECT OF YOGIC EXERCISES ON LEVEL OF ASPIRATION AND EMOTIONAL INTELLIGENCE AMONG THE ADOLESCENTS
Authors: Adhikari Amalesh
Published: May 2022

An attempt has been made to investigate the Effect of Yogic Exercises on Level of Aspiration and
Emotional Intelligence among the Adolescents. Fifty male students of U.G. college level were practiced
different types of yogic exercises like Surya Namaskar, Asanas, Pranayam and Meditation for eight weeks by maintaining a
schedule. Level of Aspiration was measured by Mahesh Bhargava and M. A. Shah's level of aspiration scale and Emotional
Intelligence was measured by Mental Health Battery by Singha and Gupta. In results, it was found that there was difference
between pre-test and post-test. So, it was evident that yogic exercises impact signicantly on level of aspiration among the
adolescents but no signicant difference in emotional intelligence.
A PRESENTATION OF TRANSVERSE TESTICULAR ECTOPIA – A CASE OF UNILATERAL DOUBLE TESTIS
Authors: Santhi B. , Sudha Sudha , Munuswamy Dharan
Published: May 2022

Testicular Ectopia is an extremely rare anomaly in which deviation of testis descent in unilateral location
of both testis. It is usually associated with an inguinal hernia with spermatic cord of the ectopic testis
originating from the appropriate side. We report a case of U/L double testis presented with an inguinal hernia in a 26 year old
male patient.
THE NECK SWELLING – AN UNEXPECTED VISITOR
Authors: Santhi B. , Balasubramaniyam A. , R Kirthika.
Published: May 2022

INTRODUCTION: Thyroid lipomatosis is an inquisitive rare entity whose etiology is unknown.
Investigations such as USG, CT, MRI can detect the presence of macroscopic fat in the thyroid gland .
Conrmation using ne needle non-aspiration cytology(FNNAC). Only 9 cases of papillary carcinoma associated with
lipomatosis of thyroid are reported so far.
Meertalig opvoeden
Authors: Orioni Marinella
Published: May 2022

Meertalig opgroeien is een mooi cadeau voor kinderen. Ze switchen moeiteloos van de ene naar de andere taal, het is goed voor hun cognitieve ontwikkeling en ze bouwen een enorme woordenschat en een groot referentiekader op. Maar meertalig opvoeden gaat niet vanzelf. Meertalige gezinnen stuiten op dezelfde moeilijkheden en vragen. Hoe leert mijn kind twee of drie talen tegelijk, is dat vermoeiend en hoe werkt het in zijn brein? Wat is voldoende taalaanbod en hoe bied ik dat aan? Hoe verbeter ik mijn kind? Is het erg als mijn kind zijn talen mixt? Wanneer kan ik eigenlijk het beste met de meertalige opvoeding beginnen? Het doel van dit boek is om deze en vele andere vragen te beantwoorden en om advies te geven om zo ouders en opvoeders een handje te helpen. Meertalig opvoeden is een handboek vol informatie, anekdotes en wetenschappelijke weetjes over meertalig opvoeden. Een must voor iedereen die meertalige kinderen opvoedt. Marinella Orioni is Nederlandse van Italiaanse afkomst en moeder van twee drietalige dochters. Na haar studie Nederlands werkte zij onder meer als docent Nederlands aan de Université Lille 3 en aan het Institut Néerlandais in Parijs. Tegenwoordig is ze naast het schrijven actief met lezingen en workshops meertaligheid en interculturaliteit in binnen- en buitenland. Eerder verschenen van haar Het meertalige kind en het kinderboek Hoeveel talen spreek jij?
A IMPORTÂNCIA DE ESTUDOS DE AVALIAÇÃO E PERCEPÇÕES SOCIOLINGUÍSTICAS
Authors: Oushiro Lívia
Published: May 2022

Este trabalho busca argumentar que (i) assim como a produção linguística, as avaliações e as percepções são demonstravelmente variáveis e ordenadas; e (ii) os estudos sobre avaliações e percepções são fundamentais não só para a compreensão sobre processos de variação e mudança linguística (Weinreich, Labov & Herzog, 2006 [1968]), mas também para a promoção do respeito linguístico (Scherre, 2020). Para tanto, resenham-se inicialmente alguns estudos que tratam de avaliações e de percepções, e que demonstram a sistematicidade de seus padrões de variação; em seguida, apresenta-se sinteticamente um método para modelagem de campos indexicais (Eckert, 2008), conceito que permite operacionalizar os múltiplos significados sociais de variantes linguísticas. Argumenta-se, em última instância, que os próprios linguistas ainda pouco conhecem sobre os mecanismos de associação entre certas variantes e significados sociais, e que a ampliação de estudos sistemáticos sobre avaliações e percepções sociolinguísticas é peça-chave para o combate ao preconceito linguístico e a promoção da diversidade linguística.

Palavras-chave: avaliações e percepções linguísticas; significados sociais; respeito linguístico.
VARIAÇÃO DISCURSIVA E ENSINO DE LÍNGUA PORTUGUESA: CONECTORES EM TEXTOS NARRATIVOS ESCRITOS
Authors: Tavares Maria Alice
Published: May 2022

Neste texto, mostro que pesquisas sobre variáveis discursivas são excelentes fontes de informações para o tratamento de itens discursivos nas escolas de nível básico. Os exemplos provêm de pesquisas sobre os conectores E e AÍ. Estudos sociolinguísticos (ABREU, 1992; GÖRSKI; TAVARES, 2013; FREITAG et al., 2013, entre outros) observaram problemas no uso desses conectores em textos escritos por alunos de diferentes níveis de escolaridade. Por um lado, há uma tendência de alta frequência do AÍ em textos de indivíduos em fases iniciais de escolarização. Por outro lado, há uma tendência de alta frequência do E em textos de indivíduos com maior tempo de escolarização. Com base nessas descobertas, apresento sugestões para a abordagem a conectores no ensino básico, distribuídas em três eixos: (i) experienciação e análise linguística; (ii) avaliação sociolinguística; e (ii) aplicação na produção de textos. Defendo que a adoção de um embasamento sociolinguístico para o ensino de língua portuguesa nos permite explorar com profundidade características morfossintáticas, semânticopragmáticas e estilísticas de itens discursivos.

Palavras-chave: Variação discursiva. Ensino. Conectores.
Some Very Personal Reflections on the Rules, Rulemaking, and Reporters
Authors: Miller Arthur
Published: May 2022

My entry into the world of federal rulemaking was one of those unpredictable but welcome fortuities of life. In early 1961, more than a half century ago, I was a happy and progressing associate in a prominent medium-sized, Wall Street, New York City law firm. Columbia Law School approached me to be the Associate Director of its newly formed Project on International Procedure. They dangled several attractive incentives: I could try my hand at teaching some civil procedure; hobnob with the giants of the Columbia faculty, like Herb Wechsler, Walter Gellhorn, Maury Rosenberg, and Jack Weinstein; and take my first trip to Europe to work with proceduralists in several countries on international judicial assistance matters.
EARLY PREDICTION OF SEPSIS USING MACHINE LEARNING ALGORITHM: A BRIEF CLINICAL PERSPECTIVE
Authors: Dr. A. A. Bardekar  , Rajshree Datey  , Rohini Mankar  , Saukhya Jainwar  , Sampada Gole  , Isha Upadhye
Published: May 2022

Sepsis is a worldwide cause of death owing to infection and associated immune system response. In situations of septic shock, mortality rates are highest in both developed and underdeveloped countries. Sepsis is a medical illness that requires immediate medical attention but can be avoided with advance warning. Sepsis affects an estimated 30 million people worldwide, with more than 6 million people dying each year. Among them More than 4.2 million new born and children are at risk of contracting the disease. To treat Sepsis, hospitals spend $24 billion (about 13% of all healthcare spending in the United States). The importance of early identification of sepsis in improving sepsis outcomes cannot be overstated. Each hour of delay in treatment increases the risk of death by 4 to 8%. As a result, developing a good model that may be able to tackle this problem becomes urgent and critical. We want to analyse, assess, and design an algorithm that will help us address some of the problems we’ve had when attempting the project.
KEYWORDS: Sepsis, Machine learning, early prediction, Supervised learning, KNN.
III CICLO DE LEITURA E ESTUDOS DO PENSAMENTO DE PAULO FREIRE:
Authors: Dos Anjos São Pedro Márcio , Vielmo Paula
Published: May 2022

Este trabalho objetiva compartilhar as vivências e aprendizagens no III Ciclo de Leitura e Estudos do Pensamento de Paulo Freire, por meio de um relato de experiência, oportunidade em que a autoria se conheceu. O Ciclo se organizou em torno de cinco encontros virtuais entre março e setembro de 2021; estudou o livro Educação como Prática da Liberdade, integrando as comemorações do centenário do patrono da educação brasileira. Ademais, adotou como metodologia a troca de cartas com outro grupo, indicado pela coordenação do evento. O essencial desta experiência ocorre pela Pedagogia da Correspondência em Paulo Freire, que possibilitou a autora e o autor além de aprofundamento teórico, a prática em suas atividades profissionais como educadora e educador. Foi uma experiência significativa para ambos, contribuindo ainda para inspirar outras educadoras e educadores na leitura coletiva de Paulo Freire.
PERCEPÇÕES DOS GESTORES ESCOLARES E PROFESSORES SOBRE AS IMPLICAÇÕES DAS VISITAS DE SUPERVISÃO PEDAGÓGICA
Authors: Gomundanhe Almeida Meque , Choe Joao Francisco de Carvalho
Published: May 2022

Este artigo tem como tema percepções dos gestores escolares e professores sobre as implicações das visitas de supervisão pedagógica: estudo de caso da Escola Primária completa Eduardo mondlane-cidade de chimoio. Por isso, o objectivo deste estudo consiste em analisar as percepções dos gestores escolares e professores sobre as implicações das visitas de supervisão pedagógica na Escola Primária Completa Eduardo Mondlane, localizada na cidade de Chimoio, em Moçambique.  Metodologicamente, adoptou-se uma abordagem qualitativa e quantitativa associada a revisão bibliográfica e as técnicas de questionário e a observação direta. O questionário foi aplicado a 10 professores, um director da escola, um director adjunto pedagógico, um coordenador do 1º ciclo e a uma coordenadora do 2º ciclo. Os resultados obtidos mostraram que a supervisão pedagógica contribui para o desenvolvimento profissional dos professores por meio das interações, trocas de experiência entre o supervisor e o professor.
Probabilistic Seismic Hazard Analysis of the Area of Tajikistan Applied to Seismic Design
Authors: Ischuk Anatoly R. , Lindholm Conrad , Ilyasova Zuhra G. , Murodkulov Shohruh
Published: May 2022

In current Probabilistic Seismic Hazard Analysis we analyzed an area and fault models. Shallow crust and deep earthquakes are occurred in the area of Tajikistan, and used two area models for shallow earthquakes and one area model for the deep earthquakes. Additionally, we used so called “Woo’s model” or “point model” which is based on the past seismicity more directly.  Six active fault databases for Central Asia and specifically for Tajikistan were used to create the fault model.Software CRISIS2015 and recent Ground Motion Prediction Equations were used in the computation. A grid with 0.1 degree of latitude and 0.1 degree of longitude covered the study area, was created for calculations, and for each 9744 grid points we calculated the spectral accelerations from 0.01 s (PGA) to 3.0s, and for 5 exceedance probabilities in 50 years.For easy application of the results in seismic design, all calculations were made for three values of Vs30, corresponding to 3 categories of the soils in the existing Seismic Design Code in Tajikistan.Special 15 Excel sheets were created for engineers and designers to easy construct the uniform hazard spectra for three types of soil conditions for needed points and exceedance probabilities.
Simulation of the ethylene oxide production process in ChemCAD® simulator
Authors: Pérez Sánchez Amaury , Baltá García José G. , Montalván Viart Jesús R. , Ranero González Elizabeth , Pérez Sánchez Eddy J.
Published: May 2022

Ethylene oxide is an important industrial chemical compound used as an intermediate in the production of glycols and other plastics. In the present work, the process of ethylene oxide (EO) production from the catalytic oxidation of ethylene was simulated using the ChemCAD® simulator. Heat curves were obtained for each of the shell and tube heat exchangers used, while the flow rate and composition of the most important streams involved in the production process were determined. A sensitivity study was also carried out to establish the influence of a decrease in the feed temperature of the wash water to the absorbers on the amount of EO to be obtained in the distillation column. 22,163.5 kg/h of EO is obtained from the top of the distillation column with a purity of 98.29 %. The wash water should be fed to the absorbers at a temperature of 5 ºC to maximise the amount of EO to be obtained in the distillation column.
Analysis of clay ceramic microstructure with the glass waste incorporation
Authors: Zaccaron Alexandre , Frizzo Rafael G. , Zanoni Elton T. , Nieves Leidy J. , Rosso Fábio , Nandi Vitor S. , Montedo Oscar R. K. , Bernardin Adriano M.
Published: May 2022

The study examined the microstructure of ceramics with the addition of glass waste at different temperatures ranging from 800 to 1000 °C. Samples were molded by piston without vacuum, with the incorporation of 20% (weight) of glass bottles, with coarse particles, for a better identification. The raw materials were analyzed chemically and mineralogically by XRF and XRD. The microstructural characterization was carried out by scanning electron microscopy, SEM and optical microscopy, in order to analyze the behavior of grain boundary and the interaction between the materials. The results showed that there is compatibility between the materials, where the increase in temperature causes a greater interaction, but when this temperature exceeds 900 ° C, pores appear in the glass, a phenomenon known as overfiring.
Genetic and epi-genetic alterations of the PTEN gene: key in the relationship between type 2 diabetes and cancer
Authors: Ayala Schimpf Alan Rolando , Formichela María Mercedes , Mascheroni María Betania , Rivero Donovan , Chamorro Marcela Luján , Portillo Valeria , Zapata Pedro Darío , Ferri Cristian Alberto
Published: May 2022

Cancer pathogenesis has been associated with genetic and epigenetic alterations that may lead to the inactivation or decrease of tumor-suppressor genes, such as the PTEN gene. In particular, alterations in the PI3K/PTEN signaling pathways are related to abnormalities associated with diabetes, metabolic syndrome, obesity and cardiovascular diseases. The aim of the study was to evaluate whether the expression levels of the PTEN gene, the 32-bp deletion in the PTEN gene, and the methylation in the PTEN promoter are associated with Type 2 Diabetes Mellitus(T2DM) and cancer development. Peripheral blood samples were obtained from a total of 70 patients of both sexes: 40 patients with T2DM and 30 patients with T2DM and cancer(T2DM+C). In this a novel report that assesses the upregulation of PTEN in T2DM, we observed that PTEN expression is higher in T2DM patients than in healthy individuals and markedly lower in T2DM patients with cancer than in T2DM patients without cancer. Hypermethylation of the PTEN promoter is more frequent in T2DM patients with cancer. Genetic and epigenetic alterations of the PTEN gene may be a key in the relationship between T2DM and cancer. PTEN expression may serve as a potential candidate biomarker for cancer development in T2DM patients.
Pengaruh Disiplin Kerja, Kompensasi dan Beban Kerja Terhadap Prestasi Kerja Karyawan Pada PT Kabelindo Murni, Tbk
Authors: Haura Ghaisani , Febrianti Reni , Ratih Susiana Dewi
Published: May 2022

Organisasi di era global saat ini dituntut untuk memiliki keunggulan kompetitif baik dari segi kualitas produk, layanan, biaya, dan sumber daya manusia yang profesional. Tujuan dari penelitian ini adalah untuk mengetahui apakah disiplin kerja, kompensasi, dan beban kerja berpengaruh terhadap prestasi kerja pada PT. Kabelindo Murni Tbk. Metode yang digunakan adalah kuantitatif dengan pendekatan deskriptif menggunakan skala pengukuran yang digunakan untuk mengukur variabel yaitu skala Likert.  Populasi 50 orang, maka teknik pengambilan sampel menggunakan Sampling Jenuh. Data yang diperoleh merupakan data primer yang merupakan hasil jawaban responden terhadap kuesioner yang dibagikan. Teknik analisis data yang digunakan adalah uji validitas, reliabilitas, uji asumsi klasik, analisis regresi berganda, dan uji hipotesis. Hasil penelitian ini menunjukkan bahwa hasil uji simultan (Uji F) antara Disiplin Kerja (X1), Kompensasi (X2), dan Beban Kerja (X3) terhadap Prestasi Kerja (Y) menunjukkan nilai F hitung sebesar 37.691 F tabel 2,79 dengan nilai signifikansi 0,000 0,05 dan koefisien determinasi 71%. Kesimpulan bahwa disiplin kerja, kompensasi, dan beban kerja secara simultan berpengaruh signifikan terhadap prestasi kerja dan hubungan antara variabel bebas dengan variabel terikat kuat. Saran agar perusahaan memaksimalkan karyawannya dalam hal ketertiban, ketepatan dan prosedur kerja yang aman serta perusahaan dapat beradaptasi dengan lingkungan sehingga penelitian lebih lanjut.Kata Kunci: Disiplin Kerja, Kompensasi, Beban Kerja, Prestasi Kerja.
Pengaruh Kualitas Produk Dan Penetapan Harga Terhadap Kepuasan Konsumen Air Minum Isi Ulang
Authors: Suryaningrat Yurika , Sutrisno Sutrisno , Ratih Susiana Dewi
Published: May 2022

Air minum secara langsung berkaitan dengan tubuh manusia, yang harus selalu terjaga kualitasnya agar tidak membahayakan tubuh manusia. Salah satu pemenuhan kebutuhan air minum yang menjadi alternatif saat ini yaitu dengan menggunakan air minum isi ulang, yang dilayani  oleh usaha depo isi ulang. Sebagai sebuah unit usaha, depo isi ulang juga harus mempunyai keunggulan bersaing dari sisi  kualitas produk, penetapan harga serta pemasaran yang profesional. Tujuan penelitian ini adalah untuk mengetahui apakah kualitas produk,  dan penetapan harga mempengaruhi kepuasan konsumen pada pengguna depot air minum isi ulang Top Water.Metode yang digunakan adalah kuantitatif dengan pendekatan deskriptif dengan menggunakan skala likert. Sampel sebanyak 95 responden., Teknik analisis data yang digunakan adalah uji validitas, uji reabilitas, uji asumsi klasik, analisis regresi berganda, dan uji hipotesis.Berdasarkan hasil uji diperoleh variabel kualitas produk dan penetapan harga secara parsial berpengaruh terhadap kepuasan. Secara bersama sama kedua variabel berpengaruh secara positif dan signifikan terhadap kepuasan konsumen. Hasil uji koefisien determinasi (R2) 0,643, berarti 64% kepuasan konsumen pada produk depot air minum isi ulang top water benar benar di pengaruhi oleh variabel independen yaitu ( kualitas produk dan penetapan harga ) sedangkan sisanya sebesar 36% di pengaruhi oleh variabel lain yang tidak ada dalam penelitian ini. Diharapkan dengan tetap mempertahankan kualitas produk dan harga yang sesuai dengan harapan konsumen, maka kepuasan konsumen akan tetap terjaga. Penelitian lebih lanjut disarankan  menggunakan variabel lain seperti promosi, penentuan lokasi dan distribusi.Kata Kunci : Kualitas Produk, Penetapan Harga, Kepuasan Konsumen, Air Isi Ulang