bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of proto-type Tarim Basin in the late Precambrian and the dynamic mechanism of its evolution
Authors: Chang Haining , Hou Guiting , Huang Shaoying , Luo Caiming , Xia Jinkai , Zhong Ziqi , Li Xiang , Wei Lunyan
Published: June 2023

Tarim Basin has undergone an intricate tectonic evolution history ever since its formation from two discrete terranes in Neoproterozoic rather than in the Paleoproterozoic. More precisely, the amalgamation is assumed to happen during 1.0–0.8 Ga based on plate affinity. As the beginning of a unified Tarim block, studies of Tarim Basin in the Precambrian are basic and important. After the amalgamation of south and north paleo-Tarim terranes, Tarim block was experiencing a complicated tectonic process of being affected by mantle plume related to the breakup of Rodinia supercontinent in the south, and compressed by the Circum-Rodinia Subduction System in the north. The breakup of Rodinia supercontinent finished in the late Sinian Period, leading Kudi Ocean and Altyn Ocean to open and separating Tarim block from itself. According to the residual strata thickness, drilling data, and lithofacies distribution, the proto-type basin and tectono-paleogeographic maps of Tarim Basin in the late Nanhua Period and Sinian Period are reconstructed. With these maps, the characteristics of the rifts are revealed. Two rift systems were developed inside the unified Tarim Basin in the Nanhua Period and Sinian Period, one back-arc rift system in the northern margin and the other aulacogen system in the southern margin. The azimuth distribution of the rifts in Quruqtagh showed a predominant NE-SW trend, and the rifts in Aksu trended mainly NW-SE, while the rifts in Tiekelike trended SW-NE. With a three-dimensional elastic FEM (Finite Element Method) model that includes all rifts and deposited areas in Tarim Basin, applying the southern subduction and northern mantle upwelling properly to get the paleotectonic mian stress axes and the differential stress field, the dynamic mechanisms of rifts evolution are proved to be related to the peripheral tectonic environment mentioned above.
Real-time scene classification of unmanned aerial vehicles remote sensing image based on Modified GhostNet
Authors: Shen Xiaole , Wang Hongfeng , Wei Biyun , Cao Jinzhou
Published: June 2023

Unmanned Aerial Vehicles (UAVs) play an important role in remote sensing image classification because they are capable of autonomously monitoring specific areas and analyzing images. The embedded platform and deep learning are used to classify UAV images in real-time. However, given the limited memory and computational resources, deploying deep learning networks on embedded devices and real-time analysis of ground scenes still has challenges in actual applications. To balance computational cost and classification accuracy, a novel lightweight network based on the original GhostNet is presented. The computational cost of this network is reduced by changing the number of convolutional layers. Meanwhile, the fully connected layer at the end is replaced with the fully convolutional layer. To evaluate the performance of the Modified GhostNet in remote sensing scene classification, experiments are performed on three public datasets: UCMerced, AID, and NWPU-RESISC. Compared with the basic GhostNet, the Floating Point Operations (FLOPs) are reduced from 7.85 MFLOPs to 2.58 MFLOPs, the memory is reduced from 16.40 MB to 5.70 MB, and the predicted time is improved by 18.86%. Our modified GhostNet also increases the average accuracy (Acc) (4.70% in AID experiments, 3.39% in UCMerced experiments). These results indicate that our Modified GhostNet can improve the performance of lightweight networks for scene classification and effectively enable real-time monitoring of ground scenes.
Konstruk Budaya Populer Korea Terhadap Aktivitas Sosial Mahasiswa (Studi Kasus Mahasiswi UIN Sunan Kalijaga Yogyakarta)
Authors: Putri Sri Hati
Published: June 2023

Penelitian ini berbicara tentang Konstruk Budaya Populer Korea Terhadap Aktivitas Sosial Mahasiswa Studi Kasus Terhadap Mahasiswa UIN Sunan Kalijaga Yogyakarta. Tujuan dari penelitian ini untuk mengetahui bagaimana konstruk Budaya Populer Korea dalam mempengaruhi aktivitas sosial mahasiswa dan untuk mengetahui dampak apa saja yang mempengaruhi perubahan sosial mahasiswa. Penelitian ini menggunakan metode kualitatif atau qualitative research. Hasil eksplorasi dari Konstruksi Drama Korea harus terlihat dari interaksi yang dimulai dari proses Eksternalisasi, Objektifikasi dan Internalisasi. Ini harus dilihat dari tiga sudut pandang, khususnya bagian dari kepribadian pemeran, topik cerita, dan gaya berpakaian para pemain. Budaya populer Korea dilihat dari kalangan mahasiswi pada umumnya akan meniru gaya, karakter, dan kisah Drama Korea tersebut. Pertunjukan Korea memberikan efek positif, misalnya, meningkatnya informasi tentang keahlian, budaya Korea, dialek Inggris serta Korea dan lebih jauh lagi untuk menabung lebih banyak. Selain itu, mahasiswa UIN Sunan Kalijaga juga dapat membuka diri ke dunia luar dan mendapatkan banyak teman baru. Akibat buruknya adalah pandangan mahasiswi tentang gaya hidup mereka sendiri telah berubah, malah mereka umumnya akan memuji budaya Korea, berubah untuk semua maksud dan tujuan, mimpi terlalu tinggi dan lupa waktu.
[This study talks about the Korean Popular Culture Constructs on Student Social Activities Case Study Against Students of UIN Sunan Kalijaga Yogyakarta. The purpose of this study is to find out how the construct of Korean Popular Culture affects student social activities and to find out what impacts affect student social change. This research uses qualitative or qualitative research methods. The results of the exploration of Korean Drama Construction must be seen from the interaction that starts from the process of Externalization, Objectification and Internalization. This has to be seen from three points of view, particularly in terms of the personality of the cast, the topic of the story, and the style of dress of the players. Korean popular culture seen from female students in general will imitate the style, character, and story of the Korean Drama. Korean shows have a positive effect, for example, information about skills, culture in Korea as well as Korea and furthermore to save more. In addition, UIN Sunan Kalijaga students can also open themselves to the outside world and make many new friends. The bad result is that female students' views on their own lifestyle have changed, instead they will generally praise Korean culture, change for all goals and objectives, dream too high and lose track of time.]
Fluid Flow Regimes Analysis on Drilling Fluid Circulation for Cuttings Lifting in Vertical Drilling Oil Wells
Authors: Agriandita Isnani , Yudiantoro Ismanu , NR Niken Ayoba
Published: June 2023

Fluid Flow during the circulation of the drilling fluid is an important parameter that affects the process of successful lifting of cuttings during drilling activities. Researcher analyzed the regimes of the drilling fluid flow in vertical drilling wells through the analysis of the velocity calculation of the drilling fluid in the pipeline at conditions in the Drillpipe (v DP) of 21.11791 fps and in drill collar of (v DC) is 42.98293 fps, the velocity of drilling fluid in the annulus between the Casing and the Drill pipe is 1.14993 fps, 1.373781 fps between Open Hole and Drill pipe, and 1.594947 fps between Open Hole and Drill Collar, the critical velocity of drilling fluid in the pipeline and in the annulus, Reynolds number in the pipeline is 15986.36, inside Drill Collar of 22807.21, and in the annular between the Casing and the Drill pipe is 2847.435, between Open Hole and Drill pipe 3037.264, and 2679.938 between Open Hole and Drill Collar, and the velocity at which the drill cutting drops when in the annulus in all three zones is 0.14914 fps. The results of the analysis of fluid flow that occurs are found that in the pipe there is a turbulent flow and in the annulus a laminar flow occurs. In addition, the results of the analysis of the comparison between the velocity of the drilling fluid in the annulus and greater than the velocity of descent of the cuttings show that the cuttings can be lifted by the drilling fluid successfully. This indicates that the fluid lifting process is successful.
A method for quantification of noise non-uniformity in computed tomography images: A computational study
Authors: Anam Choirul , Naufal Ariij , Matsubara Kosuke , Fujibuchi Toshioh , Dougherty Geoff
Published: June 2023

In computed tomography (CT), the noise is sometimes non-uniform, i.e. the noise magnitude may vary with the gradient level within the image. The purpose of this study was to quantify the noise non-uniformity in CT images using appropriate 1D and 2D computational phantoms, and to validate the effectiveness of the proposed concept in images filtered by the bilateral filter (BF), as an example of a non-linear filter. We first developed 1D and 2D computational phantoms, and Gaussian noises with several noise levels were then added to the phantoms. In addition, to simulate the real form of noise from images obtained in a real CT scanner, a homogeneous water phantom image was used. These noise levels were referred to as ground truth noise (σG). The phantoms were then filtered by the bilateral filter with various pixel value spreads (σ) to produce non-uniform noise. The original gradient phantoms (G) were subtracted from both the noisy phantoms (IN) and the filtered noisy phantoms (IBF), and the magnitudes of the resulting noise for each gradient were computed. The noise-gradient dependency (NGD) curve was used to display the dependency of noise magnitude on image gradient in the non-uniform noise. It is found that for uniform noise, the magnitude of noise was constant for all gradients. However, for non-uniform noise, the measured noise was dependent on the gradient levels and on the strength of the BF for every ground truth noise (σG). It was found that the noise magnitude was large for the large gradients and decreased with the magnitude of the image gradient.
Kerentanaan dan Strategi Adaptasi Masyarakat Terhadap Bencana Rob di Kawasan Pesisir Kecamatan Sayung Kabupaten Demak
Authors: Sarasadi Annisa , Rudiarto Iwan
Published: June 2023

Sayung Subdistrict is part of Demak Regency which is located in the northern-coastal region has experienced tidal floods with vulnerable socio-economic in decades. This study aims to determine the level of community vulnerability and the effectiveness of the community adaptation strategy in dealing with the tidal flood. Meanwhile, quantitative and qualitative approaches are used to explore people's adaptations and vulnerability. By used a random sampling technique, people in the Siwulan Village, Bedono Village, Timbulsloko Village and Surodadi Village  was choosen as the research's population. The variables are: community's vulnerability (physical, economic, social and cultural); and adaptation strategies. Questionnaires, observations and documentation has been done for data collecting. The Livelihood Vunerability Index (LVI) is used to measure and analyze the variables by using a score-calculation with 4 criteria including very-effective, effective, less-effective, ineffective. Based on the data, structural adaptations, including  road dredging, embankment construction and raise floor elevation are considered effective to very effective. While raising household furniture was considered effective to very-effective by the people of  Bedono Village, Timbulsloko Village and Surodadi Village, while the Sriwulan Village community considered the structural adaptation to be less effective if it was not accompanied by the elevation of the building floor.
Preferensi Masyarakat Terhadap Penggunaan Telemedicine Sebagai Pendukung Sarana Kesehatan pada Masa Pandemi Covid-19 di DKI Jakarta
Authors: Araminta Tasya Rahma , Sophianingrum Mada
Published: June 2023

The Covid-19 pandemic has become a great challenge for cities around the world, one of which is DKI Jakarta, to adapt to the impact it has. One of the biggest impacts of the pandemic is health services that become vulnerable to experiencing over capacity during the pandemic. This condition gave rise to a new phenomenon, namely the use of telemedicine as a form of community adaptation to overcome the problem of limited access to health services when a wave of COVID-19 cases occurred. As a form of public service, it is important to know the preferences of the community as users of telemedicine, so that later the benefits obtained from telemedicine can be maximized. The results of this study indicate that people's preferences for the use of telemedicine are very diverse, which people give a positive response to the use of telemedicine as a form of health service, as proved by the number of people who will continue to use it in the future. The community also uses telemedicine as a solution to the problems of conventional health services, such as the high cost of services and the service process which is considered to be complicated and take a long time. However, the use of telemedicine is still facing obstacles, one of which is the quality of the application which is considered to be still not good. The use of telemedicine can be a solution to the problems of conventional health services, because telemedicine cannot remove the existing health care system, but is complementary.
Prediksi Tutupan Lahan dalam Melihat Perkembangan Lahan Sawah di Kota Gorontalo Menggunakan Permodelan Cellular Automata
Authors: Pulukadang Muhammad Ghozali , Pigawati Bitta
Published: June 2023

Land development in Indonesia currently tends to have a significant impact on land use change. Gorontalo City is one of the provincial capitals which currently still has an area of more than 800 ha of rice fields. The growing issue related to rice fields is that 50% of the currently identified rice fields will become built up land because they have accessibility and facilities that support the development of built up land. The purpose of this study is to predict the development of land cover in the City of Gorontalo and to analyze the conversion of paddy fields into built-up land. Rice fields are productive lands that are quite important in Gorontalo City, so it is necessary to know how much the reduction is due to the development of built-up land. The dynamics of land cover changes spatially will be analyzed using the Cellular Automata (CA) model with a period of 10 years. The results obtained from this study indicate that the prediction of land cover development with a validation value of 0.55 (Accuracy of Moderate), especially built-up land in 2030 increases by 592 Ha and the conversion of paddy fields into built-up land in 2030 covers an area of 300 Ha in the District North City. The results of this study can be used as recommendations and considerations for Gorontalo City government policies in controlling land in order to achieve a sustainable city.
Antropologiczne aspekty milczenia
Authors: Olearczyk Teresa
Published: June 2023

Głównym celem badawczym artykułu jest wykazanie antropologicznych podstaw milczenia. W pracy zastosowano metodę porównawczą pozwalającą na interdyscyplinarne potraktowanie przedmiotu badań. Podjęto próbę aplikacji koncepcji godności osoby ludzkiej lubelskiego personalisty Adama Rodzińskiego w pedagogiczno-społecznych kontekstach kultury milczenia. Uzyskane wyniki poznawcze pozwalają sformułować wniosek, że milczenie jest istotnym czynnikiem kształtowania godności podmiotu rozumianej jako osobowość, wzmacniania poczucia własnej godności jednostki i ochrony jej godności ontycznej stanowiącej immanentną wartość natury ludzkiej.
Chrześcijańskie fake newsy w czasach postprawdy
Authors: Kłos-Skrzypczak Aleksandra
Published: June 2023

Niniejszy artykuł ma na celu analizę chrześcijańskich fake newsów, które od 1 stycznia 2020 roku do 1 czerwca 2022 roku pojawiły się w przestrzeni wirtualnej. Analizie poddano fałszywe wiadomości prezentowane na portalu demagog.org.pl redagowanym przez pierwszą w Polsce organizację fast-checkingową. Autorka, celem podkreślenia istoty problemu fałszywych wiadomości w Internecie i mediach społecznościowych, stara się zdefiniować takie pojęcia jak: fake news oraz postprawda. Na podstawie przedstawionych przykładów można wywnioskować, że publikacja chrześcijańskich fake newsów związana jest zawsze z interesami politycznymi czy społecznymi, a ich celem jest destabilizacja nastrojów, zmiana opinii czy sytuacji społeczno-politycznej.
Biomechanical effects of inclined implant shoulder design in all-on-four treatment concept: a three-dimensional finite element analysis
Authors: Aktas Taha , Diker Nurettin
Published: June 2023

Objectives

The aim of the present study was to assess the biomechanical behaviour of using a posterior implant design with inclined shoulder designs in all-on-four treatment via three-dimensional finite element analysis.

Methods

Implants with standard and inclined shoulder designs were modelled for posterior implants. Implants were positioned into the maxilla and mandible models according to the all-on-four concept. Compressive stresses in the peri-implant bone, the von Mises stresses in the different components of the prosthetic restoration, and movement of the prosthesis were obtained.

Results

The compressive stresses of the models with inclined shoulder design resulted in 15–58 % decrease compared with standard shoulder design. The von Mises stresses in the posterior implants reduced 18–47 %, stresses in the implant body increased 38–78 %, stresses in the abutment screw reduced 20–65 %, stresses in the framework of prosthesis reduced 1–18 % and deformation of the prosthesis was reduced 6–37 % in the models of inclined shoulder design compared with models of standard shoulder design. The compressive and von Mises stresses were generally higher in the mandible models than in the maxilla models for standard and inclined shoulder designs.

Conclusions

All evaluated components of the simulated treatment except for posterior abutment bodies showed better biomechanical behaviour with inclined shoulder design. The clinical success of all-on-four treatment maybe enhanced by using posterior implants with an inclined shoulder design.
Assessment Literacy: Changing Cultures, Enculturing Change in Hong Kong
Authors: Davison Chris
Published: June 2023

Teacher assessment literacy has gained significant attention in recent years due to its critical role in learning and teaching. Various theoretical and empirical conceptualizations of this construct have been emerging with more recent emphasis on building teachers’ knowledge and skills. The aim is to make highly contextualized, fair, consistent and trustworthy assessment decisions to inform learning and teaching to effectively support both student and teacher learning. This article explores changes in secondary English language teachers’ assessment literacy following the introduction of school-based assessment for learning as part of high stakes secondary school assessment reform in Hong Kong. Drawing on teacher questionnaires completed by almost 4,500 teachers who undertook a common professional development course conducted over the first six years of assessment reform (2005 – 2011), this paper explores the impact of professional development on teachers’ assessment literacy. Despite Hong Kong’s deeply ingrained competitive examination-oriented culture, an analysis of the quantitative and qualitative data from pre- and post-program evaluations demonstrate signs of positive change in teacher attitudes, confidence and practices, in particular in using assessment criteria, designing and implementing appropriate assessment tasks, involving learners more actively in the assessment process, making trustworthy assessment decisions and providing effective feedback and feed-forward to students to improve student learning. The findings of the study suggest that changes in assessment culture are possible, provided teachers are well supported. The implications for assessment reform and for the development of teacher assessment literacy more generally are also discussed.
Dynamic recrystallization in friction stir welded AA2014 aluminium alloy joints to replace riveted joints
Authors: Chinnasamy Rajendran , Srinivasan Kasi , Balasubramanian Visvalingam , Balaji Haridasu , Vinoth Kumar Mari , Ragunathan Seerangan
Published: June 2023

The demand for lightweight materials (aluminium and magnesium alloy) in structural applications is increasing due to strength ratio, corrosion resistance, formability, and recyclability. Fusion welding of aluminium and its alloy is difficult due to the formation of hot cracking, alloy segregation, porosity, etc. Henceforth, fusion welding is not an ideal process for joining aluminium and its alloy. Steel rivets are being used to join similar and dissimilar alloys in different joint configurations. Since the use of steel rivets, aircraft weight has increased drastically. Although, dissimilar metal corrosion has been encountered. These two are the main problems in structural fabrication industries. The solid-state welding friction stir welding process eliminates the issues mentioned earlier. This process can weld materials well below the melting point. Moreover, the formation of weld in the weld line could be achieved by severe plastic deformation and recrystallized grains. This metallurgical joint may replace the rivets.
Crystal structure of 3-(thiazol-2-ylcarbamoyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid, C11H12N2O4S
Authors: Song Jinqing , Cui Beibei , Mi Xia , Zhang Jingyu
Published: June 2023

C11H12N2O4S1, orthorhombic, Pbca (no. 61), a = 11.08447(14) Å, b = 10.71473(16) Å, c = 19.5463(3) Å, V = 2321.46(6) Å3, Z = 8, R

gt
(F) = 0.0450, wR
ref(F
2) = 0.1275, T = 293(2) K.
Investigation of the roles of TGFβ1, CUG2, TGFBI genes, and thiol-disulfide balance on prostate cancer and metastasis
Authors: Tepebaşı Muhammet Yusuf , Sancer Okan , Aslan Koşar Pınar , Koşar Alim , İlhan İlter
Published: June 2023

Objectives

Transforming growth factor-beta (TGFβ1) is involved in tumorigenesis and metastasis. It provides this effect both by disrupting the thiol-disulfide balance and through the cancer-upregulated gene (CUG2) and transforming growth factor beta-induced (TGFBI) genes in the signaling pathway. In this study, the roles of TGFβ1 and related genes, as well as thiol-disulfide balance, in the formation of prostate cancer and metastasis were investigated.

Methods

Tissue samples were taken from 33 benign prostatic hyperplasia (BPH) and 35 prostate cancer (PC) patients to determine the Gleason score and metastasis. TGFβ1, CUG2, and TGFBI gene expression levels were measured by RT-PCR. Serum prostate specific antigen (PSA) levels were measured in patients, and PSA density (PSAD) was calculated. Total thiol and native thiol measurements in serum were performed spectrophotometrically, and disulfide was calculated.

Results

In patients with prostate cancer and metastases, PSA and PSAD levels were high, while total thiol and native thiol were significantly lower (p<0.05). TGFβ1, CUG2 and TGFBI gene expression levels were higher in patients with prostate cancer and metastases and were negatively correlated with total thiol and native thiol (p<0.001).

Conclusions

As a result of our study, we determined that the increase in TGFβ1, CUG 2 and TGFBI in prostate cancer plays an important role in cancer formation and metastasis by disrupting the thiol-disulfide balance.
Effects of surfactants and enzymes on the direct determination of protein on fabric using the BCA reaction
Authors: Tsukazaki Mai , Morita Miyuki , Yoneyama Yuji
Published: June 2023

A simple and direct determination method for protein on fabric by measuring the surface reflectance of the bicinchoninic acid (BCA) reaction color has been reported. This study investigated the effects of four synthetic surfactants, six sodium fatty acids and one enzyme, as the coexisting substance on the direct determination of protein in cotton fabrics. The influence of the coexisting substance to the BCA reagent was examined. Then, seven coexisting substances present in detergents were selected, and the reflectance of reacted test swatch by protein and each coexisting substances were also measured, and then compared to the values obtained for protein alone. With the exception of sodium dodecyl sulfate and lauric acid, the concentration of the surfactants used in this study had little effect on protein determination. At low protease concentration there were no significant effects on the BCA method and determination.
A Comprehensive, Affordable, Open-Source Hardware-Software Solution for Flexible Implementation of Complex Behaviors in Head-Fixed Mice
Authors: Ozgur Ali , Park Soo Bin , Flores Abigail Yap , Oijala Mikko , Lur Gyorgy
Published: June 2023

Experiments that take advantage of head-fixed behavioral tasks have been a staple of systems neuroscience research for half a century. More recently, rodents came to the forefront of these efforts, primarily because of the rich experimental possibilities afforded by modern genetic tools. There is, however, a considerable barrier to entering this field, requiring expertise in engineering, hardware and software development, and significant time and financial commitment. Here, we present a comprehensive, open-source hardware and software solution to implement a head-fixed environment for rodent behaviors (HERBs). Our solution provides access to three frequently used experimental frameworks (two-alternative forced choice, Go-NoGo, or passive sensory stimulus presentation) in a single package. The required hardware can be built at a relatively low cost compared with commercially available solutions, from off-the-shelf components. Our graphical user interface-based software provides great experimental flexibility and requires no programming experience for either installation or use. Furthermore, an HERBs takes advantage of motorized components that allow the precise, temporal separation of behavioral phases (stimulus presentation, delays, response window and reward). Overall, we present a solution that will allow laboratories to join the growing community of systems neuroscience research at a substantially lower cost of entry.
Neural Evidence for Boundary Updating as the Source of the Repulsive Bias in Classification
Authors: Lee Heeseung , Lee Hyang-Jung , Choe Kyoung Whan , Lee Sang-Hun
Published: June 2023

Binary classification, an act of sorting items into two classes by setting a boundary, is biased by recent history. One common form of such bias is repulsive bias, a tendency to sort an item into the class opposite to its preceding items. Sensory-adaptation and boundary-updating are considered as two contending sources of the repulsive bias, yet no neural support has been provided for either source. Here, we explored human brains of both men and women, using functional magnetic resonance imaging (fMRI), to find such support by relating the brain signals of sensory-adaptation and boundary-updating to human classification behavior. We found that the stimulus-encoding signal in the early visual cortex adapted to previous stimuli, yet its adaptation-related changes were dissociated from current choices. Contrastingly, the boundary-representing signals in the inferior-parietal and superior-temporal cortices shifted to previous stimuli and covaried with current choices. Our exploration points to boundary-updating, rather than sensory-adaptation, as the origin of the repulsive bias in binary classification.

SIGNIFICANCE STATEMENTMany animal and human studies on perceptual decision-making have reported an intriguing history effect called “repulsive bias,” a tendency to classify an item as the opposite class of its previous item. Regarding the origin of repulsive bias, two contending ideas have been proposed: “bias in stimulus representation because of sensory adaptation” versus “bias in class-boundary setting because of belief updating.” By conducting model-based neuroimaging experiments, we verified their predictions about which brain signal should contribute to the trial-to-trial variability in choice behavior. We found that the brain signal of class boundary, but not stimulus representation, contributed to the choice variability associated with repulsive bias. Our study provides the first neural evidence supporting the boundary-based hypothesis of repulsive bias.
Autophagic blockade potentiates anlotinib-mediated ferroptosis in anaplastic thyroid cancer
Authors: Wu Jiajun , Liang Juyong , Liu Ruiqi , Lv Tian , Fu Kangyin , Jiang Liehao , Ma Wenli , Pan Yan , Tan Zhuo , Liu Qing , Qiu Weihua , Ge Minghua , Wang Jiafeng
Published: June 2023

Anlotinib-mediated angiogenic remodeling was delineated in various tumors. Meanwhile, we previously showed that anlotinib inhibited tumor angiogenesis in anaplastic thyroid cancer (ATC). However, the potential role of anlotinib on cell lethality in ATC remains an enigma. Herein, we found that anlotinib inhibited the viability, proliferation, and migration of KHM-5M, C643, and 8505C cells in a dose-dependently manner. Under anlotinib treatment, PANoptosis (pyroptosis, apoptosis, and necroptosis) markers were not changed; however, ferroptosis targets (transferrin, HO-1, FTH1, FTL, and GPX4) were significantly downregulated. ROS levels also increased in a concentration-dependent manner after anlotinib treatment in KHM-5M, C643, and 8505C cells. In addition, protective autophagy was activated in response to anlotinib, and autophagic blockade potentiated anlotinib-mediated ferroptosis and antitumor effects in vitro and in vivo. Our new discovery identified autophagy-ferroptosis signaling pathway which provides mechanistic insight into anlotinib-mediated cell death, and synergistic combination therapy may help develop new ATC treatment strategies.
Pre-eclampsia and Cardiovascular Disease: From Pregnancy to Postpartum
Authors: Giorgione Veronica , Cauldwell Matthew , Thilaganathan Basky
Published: June 2023

Hypertensive disorders of pregnancy (HDP) complicate approximately 10% of pregnancies. In addition to multiorgan manifestations related to endothelial dysfunction, HDP confers an increased risk of cardiovascular disease during delivery hospitalisation, such as heart failure, pulmonary oedema, acute MI and cerebrovascular events. However, the cardiovascular legacy of HDP extends beyond birth since these women are significantly more likely to develop cardiovascular risk factors in the immediate postnatal period and major cardiovascular disease in the long term. The main mediator of cardiovascular disease in women with a history of HDP is chronic hypertension, followed by obesity, hypercholesterolaemia and diabetes. Therefore, optimising blood pressure levels from the immediate postpartum period until the first months postnatally could have beneficial effects on the development of hypertension and improve long-term cardiovascular health. Peripartum screening based on maternal demographic, and clinical and echocardiographic data could help clinicians identify women with HDP at highest risk of developing postpartum hypertension who would benefit from targeted primary cardiovascular prevention.
Coronary Spasm: Ethnic and Sex Differences
Authors: Ong Peter , Hubert Astrid , Schwidder Maike , Beltrame John F
Published: June 2023

Coronary spasm (CS), which may occur at the epicardial (focal or diffuse spasm) and/or microvascular (microvascular spasm) level, is a well-established cause of myocardial ischaemia, in particular in patients with anginal chest pain despite unobstructed coronary arteries. The diagnosis of CS can be confirmed during coronary angiography by an additional provocation test with vasoactive substances such as acetylcholine. Due to partially inconsistent data from large clinical studies, especially between Asian and white CS patients, ethnic differences concerning the prevalence and angiographic patterns of CS seem to exist. Furthermore, several studies in patients with coronary vasomotor disorders pointed towards differences among male and female CS patients. This article gives an overview of ethnic- and sex-related differences in patients with CS.
The impact of patient sex on survival after unintentional trauma in Korea: a retrospective, observational, case-control study
Authors: Maeng Seung Jin , Kang Jongkyeong , Kim Myung Chun , Choi Han Zo
Published: June 2023

Objective This study aimed to describe the relationship between sex and survival in patients experiencing unintentional trauma.Methods This retrospective, national population–based observational, case-control study involved a cohort of Korean trauma patients who were transferred to an emergency department by a Korean emergency medical service from January 1 to December 31, 2018. Propensity score matching was used. The primary outcome was survival until hospital discharge.Results Of 25,743 patients with severe unintentional trauma, 17,771 were male and 7,972 were female. Prior to propensity score matching, there was no significant difference in survival among male and female patients (92.6% vs. 93.1%, P=0.105). After using propensity score matching to adjust for confounders, there was still no sex difference in survival (male, 93.6% vs. female, 93.1%; P=0.270).Conclusion Survival after severe trauma was not influenced by the sex of the patient. Further studies with patients of reproductive age and a larger study population are needed to analyze the effects of sex on survival in patients with trauma.
Return of the “Cult”
Authors: Thomas Aled , Graham-Hyde Edward
Published: June 2023

Recent years have seen an apparent “return” of normative religious and cultic language in political and media discourses, often adopted in pejorative and confrontational contexts. Arguably driven by contemporary political divisions and debates surrounding COVID-19 restrictions, terms including “cult,” “brainwashing,” and “groupthink” have reignited discourses surrounding so-called “cultic” behaviour and beliefs. We argue, however, that the “cult debate” has not returned, but rather transitioned into new and implicit conversations surrounding “good” and “bad” religion. In this special issue of Implicit Religion, we seek to avoid re-treading old ground concerning definitions of “cults,” and instead adopt a renewed approach to the academic study of normative cultic language—placing an emphasis on the ways in which these terms are used, negotiated, and understood in contemporary discourses.
‘A superb library at bargain cost’
Authors: Ainsworth Alan John
Published: June 2023

Offering access to low-cost authoritative literature, the Jazz Book Club was a successful and influential venture, publishing 66 subscription titles and 11 occasional volumes between 1956 and 1967. The Club was created to meet the demand for information by the rapidly growing post-war jazz audience in Britain. Extending the intellectual discourse of the 1930s, an educated, socially diverse generation coming to jazz in the 1940s and 1950s was serious about the music and earnest in their pursuit of information. Although the new fans were often fiercely partisan in their preferences, the Club believed its book choices would appeal broadly across the emerging jazz community. Surprisingly, the Jazz Book Club has been little researched. Using previously unexamined archival records and Jazz Book Club publications, contemporary journals and personal recollections alongside recent scholarship, this article provides the first full account of a small but important moment in British jazz history. Drawing on Karl Mannheim’s epistemology of generations, I argue that the Jazz Book Club was created to meet the demands of a young post-war generation for whom jazz assumed an unexampled measure of cultural saliency. The Jazz Book Club’s moment passed as a later generation turned away from jazz after the early 1960s.
Building Coalitions from Shared Pieties
Authors: Senda-Cook Samantha , Bloomfield Emma Frances
Published: June 2023

The Asian Rural Institute (ARI) is a Christian organization based in Tochigi, Japan that emphasizes foodlife work (working to grow food to sustain life), servant leadership, and community development. In analyzing the experiences of ARI community members, we located three themes that encapsulate ARI’s negotiation of religious environmentalism: 1) hierarchy, 2) ritual, and 3) tensions. These themes create polyvocality, or multiple voices, which we argue builds coalitions among community members at ARI through shared values. In conversation with work on religious environmentalism, this essay positions Christianity as a coalition building resource for some environmental and social justice advocates. Furthermore, we demonstrate the capacity for coalition building among groups that share pieties rather than identity and illustrate how an organization can rhetorically mobilize and emphasize some parts of its identity to its advantage while remaining committed to all of its core values.
Understanding the Relationship between Canadian Law and Settler-Colonial Land Ontologies for Contemporary Decolonisation Movements
Authors: Turner Marisa
Published: June 2023

This article uses a decolonial framework to reveal the power of legality in the settler-colonial states’ legitimation of ontological occupation. Using the 1997 Delgamuukw decision and the Coastal GasLink Pipeline as central case studies, this paper reveals that the historical interrelationship between settler-colonial land ontologies and Canadian law during the process of colonisation has influenced the Canadian court system in ways that limit possibilities for decolonisation, and recognition of Indigenous sovereignty.
BNC-FORMAÇÃO E OS CURSOS DE LICENCIATURAS
Authors: Moura Ana Paula Monteiro de , Silva Leia Soares da , Meneses Marlúcia Lima de Sousa
Published: June 2023

Este artigo faz uma análise crítica sobre a implementação da reforma curricular da educação básica referendada pela Base Nacional Comum Curricular-BNCC no ensino médio e sua relação direta com a Base Nacional Comum para a Formação de Professores da Educação Básica (BNC-Formação). Tem como referência o marco teórico publicado em revistas e periódicos científicos, desde as iniciativas de implementação da política nos sistemas públicos de ensino no Brasil, que impacta diretamente na formação inicial de professores. Questiona-se quais os entraves e riscos da reformulação curricular dos cursos superiores de licenciatura em Matemática e Física a partir da implementação da BNC-Formação? Do ponto de vista da metodologia, configura-se como um levantamento bibliográfico, com o intuito de sistematizar as principais discussões em torno da BNC-Formação, com ênfase nos documentos legais e na literatura contemporânea, nos anos de 2018 a 2021. O estudo está dividido em quatro partes, a primeira discorre sobre a BNCC no Ensino Médio; a segunda reflete sobre as críticas relacionadas à proposta de implementação da Base para os cursos de licenciaturas; a terceira analisa as possíveis implicações desta proposta para a formação inicial de professores e a quarta apresenta as considerações finais. A intenção é contribuir no campo de conhecimento na área de política e gestão educacional e sua estreita relação com a formação dos futuros professores da educação básica, bem como na ampliação da discussão sobre a organização curricular dos cursos de licenciatura nas instituições públicas de ensino superior.
Que veulent les images ? : Une critique de la culture visuelle
Authors: KAPTAN Merve
Published: June 2023

Traduit en français en 2014, le livre de W.J.T. Mitchell Que veulent les images ? : Une critique de la culture visuelle est toujours d'actualité à une époque où les images sont omniprésentes et jouent un rôle de plus en plus important dans nos vies. Les idées du livre ont influencé des domaines tels que les études visuelles, l'histoire de l'art, les études sur les médias et les études culturelles, et ont contribué à façonner notre compréhension du rôle des images dans la culture contemporaine. Il propose un examen convaincant et stimulant de la relation entre les images et les spectateurs, et de la manière dont les images influencent notre perception du monde qui nous entoure. L’ouvrage continue d'inspirer de nouvelles recherches et réflexions sur le pouvoir des images et leur relation avec l'expérience humaine.
The image of public and private schools in the opinion of teachers working there
Authors: Nowak-Gołąb Joanna
Published: June 2023

The article is related to the functioning of public and non-public institutions in Poland – special attention was paid to primary schools. The most important theoretical issues were presented, referring to the available publications. The article presents the results of own research conducted in the school year 2021/2022 among teachers working in public and non-public primary schools in one of the Małopolska cities. 48 teachers participated in the research – 24 working in public schools and 24 teachers working in non-public institutions. The questions posed in the research allowed us to obtain information on, among others, what differences in work in public and private schools are perceived by teachers, what is the offer of these schools, what is the hourly working time of teachers, what benefits are perceived in a specific place and what difficulties they encounter. The article is of a teoretycy and research nature.
Maske ve Mesafenin İlkokul Birinci Sınıf Öğretim Sürecindeki Etkisi
Authors: TÜRKSOY Enver , ALTINTAŞ Gülşen
Published: June 2023

Covid-19 pandemi sürecinde yüz yüze eğitime öncelikli olarak katılan eğitim kademelerinden biri ilkokul birinci sınıf düzeyidir. Bunun nedeni okuma yazma eğitiminin beceri odaklı olması ve eğitimin temellerini oluşturmasıdır. Yüz yüze eğitim sürecinde bulaş riskini azaltmak amacıyla maske takma ve mesafe kuralları uygulamaya konulmuştur. Bu araştırmanın amacı maske-mesafe uygulamasının ilkokul birinci sınıf öğrenme sürecine etkisinin öğretmen ve veli görüşleri doğrultusunda belirlenmesidir. Araştırmada mevcut “maske-mesafe uygulaması” durumunun detaylı bir şekilde incelenmesine olanak sunacağı düşünülen nitel araştırma felsefesine dayanan bütüncül tekli durum deseni kullanılarak yapılandırılmıştır. Araştırma ana durumu maske ve mesafe uygulamasıdır. Araştırma katılımcıları amaçlı örneklem yöntemlerinden ölçüt örneklem yöntemi kullanılarak belirlenmiştir. Araştırmaya 23 veli ve 34 ilkokul birinci sınıf öğretmeni katılmıştır. Araştırma verileri farklı iki yöntem ile toplanmıştır. Veliler ile ilgili veriler yarı-yapılandırılmış görüşme formu kullanarak yüz yüze görüşmeler yaparak; öğretmen verileri yapılandırılmış görüş formu kullanarak çevrim içi toplanmıştır. veri analizinde içerik analizine gidilmiştir. Araştırma verileri araştırmacılar tarafından eş zamanlı ve birbirinden bağımsız bir şekilde gerçekleştirilip daha sonra ortak görüş oluşturma amacıyla elde edilen veriler karşılaştırılmıştır. Veri analizinde Hermeneutik bir yaklaşım benimsenmiş olup, elde edilen veriler tümevarımsal ve tematik bir anlayış ile sunulmuştur. Elde edilen verilerin katılımcı gruplarına göre farklılaştığı görülmüştür. Öğretmen görüşleri olumsuzluklara odaklanırken, veli görüşlerinde maske ve mesafe uygulamasının önemsiz görüldüğü; başka bir ifade ile okulların açılmasının gölgesinde kalan olumlu bir olgu olarak algılandığı görülmüştür. Katılımcıların ortak görüşü noktasında uzaktan eğitim sürecinin ilkokul birinci sınıf okuma yazma sürecinde zorlayıcı bir yapı olduğu görülmüştür.
Alcoholic extracts of Teucrium polium exhibit remarkable anti-inflammatory activity: In vivo study
Authors: Al-Naemi Hamda A. , Alasmar Reem Moath , Al-Ghanim Kaltham
Published: June 2023

Teucrium polium (germander, Lamiaceae) is a local plant in Qatar that has been used in folk medicine to treat numerous illnesses. It is known for its antioxidant, analgesic, anticancer, and antibacterial activities. This study aimed to evaluate the anti-inflammatory activity of Teucrium polium (TP) extract by α-carrageen-induced paw edema in adult Sprague Dawley rats. The animals were randomly grouped into control, acute inflammation, and plant extract groups. Acute inflammation was induced by a sub-plantar injection of 100 µL of 1% α-carrageenan into the rat’s right hind paw. Three different doses of the ethanolic extract of TP were tested at different time periods (1, 3, and 5 hours). All doses of the TP ethanolic extract showed significant inhibition of α-carrageenan-induced rat paw edema in a dose-dependent manner in both early and late phases of edema formation. The size of the α-carrageen induced paw edema was significantly reduced one, three, and five hours after TP extract injection compared to the acute inflammation group. This inhibition was accompanied by high expression of interleukin 10 (IL-10) and low expression of monocyte chemoattractant protein 1 (MCP-1), IL-1β and tumor necrosis factor alpha (TNF-α). The results indicated that the ethanolic extracts of TP possess significant anti-inflammatory and potential pharmaceutical properties.
UPAYA PENGAWAS DALAM MENINGKATKAN KEMAMPUAN PROFESIONAL GURU MELALUI SUPERVISI KLINIS PADA MADRASAH IBTIDAIYAH (Ml) DI KABUPATEN BOGOR
Authors: Sumarna Cecen
Published: June 2023

Belum berfungsinya supervisi klinis secara optimal pada Madrasah Ibtidaiyah (Ml) di Kabupaten Bogor, mendorong peneliti untuk mengungkap permasalahan dengan tujuan untuk memperoleh gambaran yang jelas tentang pelaksaanaan supervise klinis pengawas madrasah terhadap guru-guru. Pendekatan dalam penilitian ini adalah naturalistik kualitatif (Bogdan dan Biklen, 1982), Kegiatan supervise klinis yang dilakukan pengawas dapat membantu guru untuk pemecahan masalah dalam pembelajaran yang berdampak positif terhadap kemampuan kinerja guru.
HUBUNGAN ANTARA EFEKTIVITAS MANAJEMEN PEMBELAJARAN DAN ETOS KERJA ANGGOTA MUSYAWARAH GURU MATA PELAJARAN (MGMP) DENGAN PROFESIONALITAS GURU
Authors: Sutrisno Budi
Published: June 2023

Profesionalitas guru harus selalu ditingkatkan dengan cara mengoptimalkan kompetensi akademik, kompetensi pedagoglk, kompetensi professional, dan kompetensi ssosialnya. Profesionalitas guru ditentukan oleh banyak factor, diantaranya adalah efektivitas manajemen pembelajaran dan etos kerja yang tinggi. Penelitian ini berusaha untuk mengetahui seberapa besar hubungan efektivitas manajemen pembelajaran dan etos keija dengan profesionalitas guru Sekolah Menengah Pertama (SMP) baik negeri maupun swasta yang ada di kecamatan Ciampel, kabupaten Karawang