bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular Characterisation of Uropathogenic Escherichia coli Reveals Emergence of Drug Resistant O15, O22, and O25 Serogroups
Authors: Prakapaite Ruta , Saab Frederic , Planciuniene Rita , Petraitis Vidmantas , Walsh Thomas J. , Petraitiene Ruta , Semoskaite Rasa , Baneviciene Rasa , Kalediene Lilija , Kavaliauskas Povilas
Published: July 2019

Background Uropathogenic Escherichia coli (UPEC) are common pathogens causing urinary tract infections (UTIs). We aimed to investigate the relationship among clinical manifestation, serogroups, phylogenetic groups, and antimicrobial resistance among UPEC.
Methods One-hundred Escherichia coli isolates recovered from urine and ureteral scrapings were used for the study. The prevalence of antimicrobial resistance was determined by using EUCAST recommendations. E. coli serogroups associated with UTI, as well as phylogenetic diversity was analysed using multiplex PCR reactions.
Results Eighty-seven strains (87%) were isolated from females, while 13 (13%) from males. A high frequency of resistance to cephalosporins (43%) and fluoroquinolones (31%) was observed. Among UTI-associated serogroups, O15 (32.8%), O22 (23.4%), and O25 (15.6%) were dominant and demonstrated elevated resistance rates. The E. coli phylogenetic group B2 was most common. These observations extended to pregnant patients with asymptomatic bacteriuria.
Conclusions Due to high rates of resistance, strategies using empirical therapy of second-generation cephalosporins and fluoroquinolones for treatment of UPEC infections should be reconsidered.
Genome-wide identification and characterization of NF-Y gene family in peanut (Arachis hypogaea L.)
Authors: Wan Qian , Luo Lu , Zhang Xiurong , Lv Yuying , Zhu Suqing , Kong Lingrang , Wan Yongshan , Liu Fengzhen , Zhang Kun
Published: July 2019

Background

Nuclear factor Y (NF-Y) gene family consists of NF-YA, NF-YB and NF-YC subfamilies. Many members of NF-Y family have been involved in plant development processes, phytohormone signaling and tolerance to stresses in Arabidopsis and other plant species. However, little attention has been given in peanut.

Results

A total of 33 AhNF-Y genes (AhNF-Ys) were identified and distributed on 16 chromosomes. A phylogenetic analysis indicated that NF-Y genes prossessed highly conservatism in different plants. Gene duplication analyze indicated that only segmental duplication were detected. The abiotic stress-related regulatory elements analysis showed that AhNF-Ys, except for AhNF-YB6, contained at least one abiotic stress response element. With RNA-seq data, the tissue/organ-specific expression and differential expression profiling under salt stress were analyzed, indicating that six selected AhNF-Y gene may play potential roles in the regulation of salt stress response. qRT-PCR results suggested that these AhNF-Y genes also responded to osmotic, ABA (Abscisic Acid) and SA (Salicylic acid) stresses.

Conclusions

In this study, thirty three AhNF-Y genes were identified in cultivated peanut and the phylogeny, gene structures, motif composition, chromosomal location, gene duplication, stress-related regulatory elements, and expression patterns were also examined. These results may contribute to functional characterization of AhNF-Y genes in further research.
WITHDRAWN: SOX13 Dependent PAX8 Expression Promotes the Proliferation of Gastric Carcinoma Cells
Authors: Bie Liang-Yu , Li Dan , Wei Yan , Li Ning , Chen Xiao-Bing , Luo Su-Xia
Published: July 2019

PAX8 is identified as a regulator in the pathogenesis of human tumors and an indicator of the prognosis for patients. However, the role of PAX8 on proliferation in gastric cancer have not been studied. This study was aimed to explore the expression pattern of PAX8 in gastric cancer, and investigate the effect of PAX8 on the proliferation of gastric cancer cells. PAX8 and SOX13 were identified to be synchronously upregulated in primary gastric cancer in human gastric cancer tissues and the gastric cancer datasets of TCGA, and gastric cancer patients of combined high PAX8 and SOX13 expression showed poor prognosis. Furthermore, SOX13 can mediate PAX8 and its targeted genes, Aurora B and Cyclin B1, expression in AGS and MGC803 cell lines. Flow cytometry and EdU incorporation assays showed that silencing PAX8 can block the cell cycle of gastric cancer cell in G1 phase and SOX13 expression can rescue the arrested proliferative process induced by PAX8 silenced in CCK8 and colony formation assays. Thus, combined SOX13 and PAX8 expression regulate the proliferation of gastric cancer cells, and both SOX13 and PAX8 play an oncogene function in gastric cancer.
Fibrin γ/γ' influences the secretion of fibrinolytic components and clot structure
Authors: Marchi Rita , Cantero Miriam , Rojas Héctor , Anglés-Cano Eduardo
Published: July 2019

Background

In healthy subjects fibrinogen γ/γ' circulates at 8-15% of the total plasma fibrinogen concentration. Elevated levels of this variant have been associated with arterial thrombosis and its diminution with venous thrombosis. The aims of the present work were to analyze the structure of the fibrin network formed on the top of human dermal microvascular endothelial cells (HMEC-1) at different fibrinogen γ/γ' concentrations, as well as its influence on the secretion of fibrinolytic components.

Methods

The kinetics of fibrin polymerization on top of HMEC-1 cells with 3, 10, and 30% fibrinogen γ/γ' was followed at 350 nm. The secretion of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI 1) by HMEC-1 were measured in the supernatant and cell lysates, after incubation with 1 nM thrombin, fibrin with 3%, and 30% fibrinogen γ/γ', using commercial kits. The influence of fibrinogen γ/γ' on fibrin structure on the surface of the HMEC-1 was followed with laser scanning confocal microscopy (LSCM).

Results

The kinetic of fibrin formation on HMEC-1 with 3% and 10% fibrinogen γ/γ' was similar. However, with 30% fibrinogen γ/γ' both the slope and final turbity were approximately 50% less. The LSCM images showed the dramatic effects of increasing fibrinogen γ/γ' from 3% to 30%. The uPA and PAI 1 concentrations in culture supernatants HMEC-1 cells treated with thrombin or 30% γ/γ' fibrin were two-fold increased as compared to basal culture supernatants and 3% γ/γ' fibrin-treated HMEC-1. In all stimulatory conditions the intracellular concentration of uPA was higher than in supernatants. In contrast, the intracellular PAI 1 concentration was decreased as compared to that measured in the supernatant, including the basal condition.

Conclusion

A concentration of 30% fibrin γ/γ' alter drastically fibrin structure on the cell surface and affects the secretion of uPA and PAI 1 through its capacity to bind thrombin.
ASSOCIATION BETWEEN EARLY CHILDHOOD CARIES AND MALNUTRITION IN A SUB-URBAN POPULATION IN NIGERIA
Authors: Folayan Morenike Oluwatoyin , Arije Olujide , Tantawi Maha El , Kolawole Kikelomo Adebanke , Obiyan Mary , Arowolo Olaniyi , Oziegbe Elizabeth O
Published: July 2019

Background

To determine the association between malnutrition and early childhood caries (ECC) in preschool children resident in sub-urban, Nigeria.

Methods

This is a secondary analysis of a cross sectional study with data generated through a household setting. Variables (sex, frequency of sugar consumption, maternal knowledge of oral hygiene, oral hygiene status) associated with ECC in a primary study conducted in the Ile-Ife, Nigeria, were adjusted for using Poisson regression analysis.

Results

Of the 370 pre-school children, 20 (5.4%) were underweight, 20 (5.4%) were overweight, 67 (18.1%) were wasting, and 120 (32.4%) were stunted. Factors associated positively or negatively with ECC were stunted, underweight, overweight and fair oral hygiene. The prevalence of ECC was lower in children who were stunted (APR: 0.16), almost seven times higher in children who were overweight (APR: 6.88), and predictively absent in children who were underweight (APR: 0) when compared with children who had normal weight. Non-significant risk indicators for ECC included consuming sugar between meals three times a day or more (APR: 2.18), having low socioeconomic status (APR: 2.4) and being female (APR: 2.9).

Conclusions

For this study population, the indicators of malnutrition – being stunted, underweight, overweight - and fair oral hygiene were risk indicators for ECC, while the frequency of sugar consumption was not a significant risk indicator. Further studies are needed to identify if there are other mediators of an association between ECC and nutrition apart from sugar consumption.
Primary Outcomes of combined cataract extraction technique with ab-interno trabeculectomy  Dual-Blade and Endoscopic cyclophotocoagulation in patients with primary open angle glaucoma
Authors: Izquierdo Juan Carlos , Mejias Josefina , Cañola Laura , Agudelo Natalia , Rubio Barbara
Published: July 2019

Purpose:  To provide an update of primary outcomes of combined phacoemulsification technique with ab-interno trabeculectomy  Dual Blade and Endoscopic cyclophotocoagulation (ECP) in patients with primary open angle glaucoma.
Methods: Retrospective case series comprised 27 consecutive eyes, with open-angle glaucoma (POAG) and cataract with combined phacoemulsification, ab-interno trabeculectomy-Kahook Dual Blade and Endocyclophotocoagulation at Instituto de ojos Oftalmosalud, Lima, Perú, between April 2017 and May 2017. Inclusion criteria were Glaucoma patients with POAG from mild to severe, according to Glaucoma Grading Scale (HODAPP), cataract condition, treatment with two or more glaucoma medications and visual field defects continued worsen. Intraocular pressure (IOP), Best corrected visual acuity (BCVA) logMAR, and number of glaucoma medications were recorded before, and 1 day, 1 week, and 1, 3, 6 and 9 months after surgery. Defining succes as IOP <14 mmHg with or without medications.
Results:  A total of 27 cases of glaucoma eyes were included. The mean IOP was 17.0±3.7 mmHg preoperatively, 11.6±1.9mmHg at 6 months, and 11.4±1.8 mmHg at 9 months(P<0.001). There was a corresponding drop in glaucoma medications from 1.9±1.41 at mean to 0.56±1.05 at 9 months (P<0.001). Preoperative best corrected visual acuity (BCVA) showed and improvement preoperative value from 0.4± 0.4 LogMAR (p= 0.001) to 0.2 ± 0.4 logMAR at 9 months. The main complication was blood reflux intraoperatively(66.7%), resolved within a few days. The mean IOP was reduce 32.9% from baseline and the qualifed succes was 92.6% at 9 months.
Conclusions:  Cataract extraction with phacoemulsification combined with ab-interno trabeculectomy Dual Blade and endoscopic Cyclophotocoagulation effectively lowered IOP and dependence on glaucoma medications.
Tranexamic acid for acute gastrointestinal bleeding (The HALT-IT trial): Statistical analysis plan for an international, randomised, double blind, placebo-controlled trial
Authors: Brenner Amy Charlotte , Afolabi Adefemi , Ahmad Syed Masroor , Arribas Monica , Chaudhri Rizwana , Coats Timothy , Cuzick Jack , Gilmore Ian , Hawkey Christopher , Jairath Vipul , Javaid Kiran , Kayani Aasia , Mutti Muttiullah , Nadeem Muhammad Arif , Shakur-Still Haleema , Stanworth Simon , Veitch Andrew , Roberts Ian
Published: July 2019

Background:
Acute gastrointestinal (GI) bleeding is an important cause of mortality worldwide. Bleeding can occur from the upper or lower GI tract, with upper GI bleeding accounting for most cases. The main causes include peptic ulcer / erosive mucosal disease, oesophageal varices and malignancy. The case fatality rate is around 10% for upper GI bleeding and 3% for lower GI bleeding. Rebleeding affects 5-40% of patients and is associated with a four-fold increased risk of death. Tranexamic acid (TXA) decreases bleeding and the need for blood transfusion in surgery and reduces death due to bleeding in patients with trauma and postpartum haemorrhage. It reduces bleeding by inhibiting the breakdown of fibrin clots by plasmin. Due to the methodological weaknesses and small size of the existing trials, the effectiveness and safety of TXA in GI bleeding is uncertain. The HALT-IT trial aims to provide reliable evidence about the effects of TXA in acute upper and lower GI bleeding.

Methods:
The HALT-IT trial is an international, randomised, double blind (participant and trial staff), placebo-controlled trial of tranexamic acid in 12,000 adults (increased from 8,000) with acute upper or lower GI bleeding. Eligible patients are randomly allocated to receive tranexamic acid (1g loading dose followed by 3g maintenance dose over 24 hours) or matching placebo. The main analysis will compare those randomised to tranexamic acid with those randomised to placebo on an intention-to-treat basis, presenting the results as effect estimates (relative risks) and confidence intervals. The primary outcome is death due to bleeding within 5 days of randomisation and secondary outcomes are rebleeding, all-cause and cause-specific mortality, thromboembolic events, complications, endoscopic, radiological and surgical interventions, blood transfusion requirements, disability (defined by a measure of patient’s self-care capacity) and number of days spent in intensive care or high dependency units. Subgroup analyses for the primary outcome will consider time to treatment, location of bleeding, cause of bleed and clinical Rockall score.

Discussion:
We present the statistical analysis of the HALT-IT trial. This plan was published before the treatment allocation was un-blinded.
Multimodal imaging of torpedo maculopathy in a Chinese woman: a case report
Authors: Ding Yuhua , Yao Bangtao , Ye Hui , Yu Yan
Published: July 2019

Background: Torpedo maculopathy is a rare, benign, and congenital macular lesion that typically appears in a ‘torpedo-shape’ and is located at the temporal macula region. This study aimed to describe in detail regarding torpedo maculopathy in a Chinese woman using multimodal imaging.
Case presentation: A 30-year-old Chinese woman with occasional yellowish-white macular lesions in her right eye during a routine examination was presented to our hospital. She had no other symptoms, and the best-corrected visual acuity of both eyes was 6/6. Funduscopic examination revealed a torpedo-shaped and mild hypopigmented lesion in the temporal macular area of her right eye. Infrared fundal (IR) images showed visible lesion contour, transverse elliptical, and with a tip pointing towards the central fovea of the macula. Microperimetry visual field appeared normal. The spectral-domain optical coherence tomography (SD-OCT) showed a normal inner retina, with mild thinner outer retina and retinal pigment epithelium in the temporal macular area, and correspondingly increased choroidal reflectivity. Other OCT findings included outer retinal loss/attenuation with significant atrophy of an intact ellipsoid zone. OCT angiography (OCTA) of choroid capillary layer revealed increased density of choroidal vasculature in corresponding to the area of the lesion, while the superficial and deep layers revealed normal vasculature. Fundus autofluorescence (FAF) revealed normal signal with slight hyperautofluorescence at the nasal lesion margin. Fundus fluorescence angiography (FFA) of the lesion showed variegated fluorescence and no leakage and change in the morphology during the whole imaging process.
Conclusions: This is the first report to include a thorough and detailed description of torpedo maculopathy by using fundal photograph, IR, microperimetry visual field, OCT, OCTA, FAF, and FFA. Multimodal imaging provides precious and detailed information to further clarify the characteristics and development of this rare disease.
Clinical Results of Intraductal Meibomian Gland Probing Combined with Intense Pulsed Light in Treating Patients with Refractory Obstructive Meibomian Gland Dysfunction: A Randomized Controlled Trial
Authors: Huang Xiaodan , Qin Qiyu , Wang Linping , Zheng Jiao , Lin Lin , Jin Xiuming
Published: July 2019

Background: This study aims to optimize the therapeutic regimen for refractory obstructive meibomian gland dysfunction (o-MGD) patients by combining intraductal meibomian gland probing (MGP) and intense pulsed light (IPL) to enhance their positive effects and reduce their limitations.
Methods: This randomized, assessor blind study includes 45 patients (90 eyes) with refractory o-MGD who were divided into 3 groups via allocation concealment: IPL (group I, received an IPL treatment course: 3 times at 3-week intervals), MGP (group II, received MGP one time), and combined MGP-IPL (group III, MGP first followed by an IPL treatment course). Standard Patient Evaluation of Eye Dryness score (SPEED), tear break-up time (TBUT), corneal fluorescein staining (CFS), meibum grade, and lid margin finding results were assessed at baseline, 3 weeks after final treatment for groups I and III, 3 and 12 weeks after MGP for group II. Six months after final treatment, the SPEED and willingness to receive any treatment again were also collected for all groups. Paired Wilcoxon, Mann-Whitney U with Bonferroni correction, and Kruskal-Wallis tests were used for data analysis.
Results: For all 3 groups, all previously mentioned indexes improved significantly following treatment (P＜0.01). MGP-IPL was better than IPL and MGP in terms of post-treatment SPEED, TBUT, meibum grade, and lid telangiectasia (P＜0.05/3). Furthermore, the MGP-IPL was better than IPL in terms of lid tenderness and better than MGP in terms of orifice abnormality (P＜ 0.05/3). Six months later, the SPEED for the MGP-IPL was also significantly lower than other groups (P＜0.05/3). Moreover, no patients in the MGP-IPL group expressed the need to be treated again compared to 35.7% or 20% of patients in the IPL or MGP groups, respectively.
Conclusions: Compared with IPL or MGP alone, the combination MGP-IPL produced best results in relieving all signs and symptoms and helping patients attain long-lasting symptom relief.
Trial registration: http://clinicaltrials.gov, ChiCTR1900021273 (retrospectively registered February 9, 2019).
Funding: This work was supported by the National Natural Science Foundation of China: [grant numbers: 81870624; 81700802] and the Major Science and Technology Projects of Zhejiang Province [grant numbers: 2017C03046].
Estimating the annual risk of infection with Mycobacterium tuberculosis among adolescents in Western Kenya in preparation for TB vaccine trials
Authors: Nduba Videlis , Hoog Anna H. van’t , de Bruijn Annefleur , Mitchell Ellen M.H. , Laserson Kayla , Borgdorff Martien
Published: July 2019

Background: Adolescents are a prime target group for tuberculosis (TB) vaccine trials that include prevention of infection (POI). The BCG vaccine is given at birth and does not prevent TB infection. TB infection, a critical endpoint for POI vaccine trials would need to be documented to estimate sample sizes in target populations.
Methods: Adolescents aged 12-18 years of age were enrolled in an area under continuous demographic surveillance. A tuberculin skin test (TST) survey was conducted as part of a study on TB prevalence and incidence. All adolescents got TSTs at enrolment and returned after 72 hours for reading. A TST of ≥10mm if HIV negative or ≥ 5mm if HIV positive, was considered positive.
Results: Of 4808 adolescents returning for TST readings (96% of those enrolled), mean age was 14.4 (SD 1.9), 4518(94%) were enrolled in school and 21(0.4%) gave a previous history of tuberculosis. Among adolescents with TST reactivity, the mean TST induration was 13.2 mm (SD 5.4). The overall prevalence of latent TB infection was 1544/4808 (32.1%, 95% CI 29.2-35.1) with a corresponding annual risk of TB infection (ARTI) of 2.6% (95% CI 2.2-3.1). Risk factors for a positive TST included being male (OR 1.3, 95%CI 1.2,1.5), history of having a household TB contact (OR 1.5, 95%CI 1.2,1.8), having a BCG scar (OR 1.5,95%CI 1.2,1.8), living in a rural area (OR 1.4, 95%CI 1.1,1.9), and being out of school (OR 1.8, 95%CI 1.4,2.3).
Conclusion: We conclude that the high TB transmission rates we found in this study, suggest that adolescents in this region may be an appropriate target group for TB vaccine trials including TB vaccine trials aiming to prevent infection.
RATIONAL USE OF THE SECONDARY RESOURCES OF THE VINEYARD AND WINEBRANDING INDUSTRY
Authors: Oganesyants L. A. , Panasyuk A. L. , Kuzmina E. I.
Published: July 2019

In the grape processing, secondary resources are primarily the remnants of the generative plant organs (berries) — sweet and fermented husks of grapes, seeds, peels, etc. However, the use of vegetative organs — vines, which are more promising, of grape leaves is promising. It is shown, that red leaves of grape are a source of phenolic compounds, resveratrol and other antioxidants, and also contain activators of enzymes, that cause venotonic and angioprotective properties. The most valuable in this respect are red grape leaves, which grow in covering areas, because on the eve of winter, as a defense against the cold, they accumulate a greater amount of resveratrol. The use of CO2 -extraction technology in the processing of red leaves makes it possible to obtain extraction cake with a high content of biologically active substances due to the destruction of the cell structure during the extraction process. At the same time, the hydrophilic extract of the extraction cake after CO2 -extraction has the greatest value, it is well soluble in water and is intended to enrich the soft juice based on grape juice with biologically active substances. A technology was developed for using CO2 extracts of grape seeds to stabilize margarine emulsions against oxidation and to increase the thermal stability of frying fats.
Assessment of the relationship between the tourism sector development and other sectors of economy
Authors: Stryzhak Olena
Published: July 2019

An assessment of a relationship between aggregated and partial indicators of the tourist sector development on one hand and other sectors of economy and society on other hand are investigated in the paper. Indicators are expressed in both direct monetary terms and rating scales. The study covers 149 countries in 2016. The results of the study indicate a positive relationship between the development of the tourist sector and the level of economic welfare of the country. This is explained by fact that tourist goods and services are subject of a second necessity and demand for they increases significantly with growth of income level. Found that there is a positive correlation between indicators of tourism sector development and indicators of quality of socio-economic environment. This may be due to fact that, on one hand, high quality socioeconomic environment stimulates visits to country; on other hand, travels stimulate growth of economy and welfare of citizens who live in territory that visited. Further analysis of aggregate of countries, divided into 4 groups by income, showed mixed results. Thus, a stronger correlation between all analyzed indicators is observed in low and high-income countries, weakening in transition to averages by a sample of values. However, such a weak relationship for some countries may be a consequence of a small share of the tourism sector in the economy. This paper differs from previous researches by focusing on a large sample of countries and reveals the relationship between tourism sector development indicators and socioeconomic environment indicators. One can speak of objectivity of results obtained, since they are confirmed both using Spearman’s correlation coefficient and Kendall’s Tau correlation.
“Scimitar” syndrome in fetus at I trimester with VACTERL-association
Authors: I.V. Novikova, S.I. Kovalev, O.A. Tarletskaya
Published: July 2019

A case of VACTERL-association in 12 weeks fetus is presented. Ultrasound examination demonstrated the
signs of anorectal atresia, atrioventricular canal, dilated renal pelvis and hyperechogenic kidneys. Pathological
examination confirmed prenatal diagnosis and revealed additional anomalies including “scimitar” syndrome,
lung sequestration accompanied with tracheoesophageal fistula without oesophageal atresia.
Prenatal diagnosis in context of formation the visual associations: “grape
snail”
Authors: O.L. Galkina
Published: July 2019

9 cases of prenatal ultrasound diagnosis of interrupted aortic arch in early gestation in context of visual
associations — the sign of “grape snail” are presented.
Prenatal ultrasound diagnosis of pelvic tumors. I. Sacrococcygeal
teratomas. Literature review
Authors: I.V. Tikhonenko
Published: July 2019

Literature review on ultrasound prenatal diagnosis of sacrococcygeal teratomas, including complications,
prognosis, management and time and mode of delivery is presented. Ultrasound images of different types of
sacrococcygeal teratomas are demonstrated.
Experience of prenatal diagnosis of true knots of the umbilical cord during
ultrasound examination in the third trimester of gestation
Authors: M.Y. Morozova, V.V. Zotov, M.S. Kovalenko et all
Published: July 2019

Despite the rapid technological advance, the expansion of prenatal ultrasound diagnosis, as well as the
accumulation of experience by both domestic and foreign experts, prenatal recognition of true knots of the
umbilical cord causes significant difficulties. Three cases of successful ultrasound diagnosis of true knots of the
umbilical cord and brief review of the literature are presented.
Prenatal diagnosis of fetal hepatoblastoma
Authors: O.I. Guseva, E.V. Shurganova
Published: July 2019

The case of prenatal ultrasound diagnosis of fetal hepatoblastoma is presented. A massive formation in
liver at 31–32 weeks of gestation was found. At 38–39 weeks of gestation woman was admitted to the perinatal
center for delivery. Ultrasound examination revealed an increase of liver formation. According to ultrasound
data, the formation is interpreted as hepatoblastoma. After birth the diagnosis was confirmed. The child was
sent for surgical treatment.
Photocatalytic degradation of Irgalite violet dye using nickel ferrite nanoparticles
Authors: Vijay Shiljashree , Balakrishnan Raj Mohan , Rene Eldon R. , Priyanka Uddandarao
Published: July 2019

Nanotechnologies have prominent applications in the field of science and technology owing to their size-tunable properties providing a promising approach for degradation of various pollutants. In this scenario, the present work aims to study the effect of nickel ferrite nanoparticles on the degradation of Irgalite violet dye by Fenton's reaction using oxalic acid as an oxidizing agent in the presence of sunlight. The effect of pH and adsorbent dosage on the rate of dye degradation was monitored. Based on these studies it was observed that 99% dye degradation was achieved for catalyst dosage of 0.2 g, 400 ppm dye concentration and 2.0 mM oxalic acid at pH 3.0 within 60 min. The studies reveal that the degradation follows pseudo-first-order kinetics and the catalyst reusability remained constant almost for five cycles. Further, nickel ferrite nanoparticles are proven to be an efficient alternative for the removal of dyes from coloured solutions.
Study of impact of acids and comparison of adsorption efficiency of Pb(II) from carbon and its modified nano-nickel coated version
Authors: Asim Tayyaba , Ahmed Riaz , Ansari Muhammad Shahid
Published: July 2019

Acidic content in wastewaters poses greater difficulty in lead removal from most adsorbents as their removal efficiency significantly decreases in acidic media. Nano-nickel coated carbon (Ni/C), compared with uncoated carbon (C), has shown a much enhanced (almost 80% higher) tendency of Pb(II) removal from solutions having different acid concentrations. All of the characterization results show the creation of more active sites and functional groups on Ni/C. The pertinent kinetic models and thermodynamics of Pb(II) adsorption have demonstrated much improved efficiency by Ni/C. Various isotherms subjected to the sorption data revealed significant increase in the sorption capacities for Ni/C. The adsorption (evidently chemisorption) kinetics are best represented by a pseudo-second-order equation. The adsorption rates in acidic solutions were much higher for Ni/C. The temperature-dependent study enabled thermodynamic parameters to be worked out for C and Ni/C; for C the values are ΔH: 19.4 ± 0.5 kJ·mol−1, ΔS: 76.1 ± 2.1 J·mol−1·K−1, ΔG298: −0.37 ± 0.01 kJ·mol−1 while for Ni/C the values are ΔH: 30 ± 1 kJ·mol−1, ΔS: 114 ± 4 J·mol−1·K−1, ΔG298: −4.56 ± 0.02 kJ·mol−1. Both cases indicate endothermic, spontaneous and entropy-driven processes.
The cartel party, consensus democracy and democracy without politics
Authors: Katz Richard S.
Published: July 2019

Although the age of the mass party as an organizational form is long in the past, the mass party remains a widely accepted normative ideal, closely connected to the idea of party government and to a voters-as-principals-parties-as-agents understanding of democracy. In evolving from mass party, to catch-all party, to cartel party European democracies have also been evolving towards an ‘anti-political’ view of government, along with models of consensus democracy and the regulatory state. This evolution helps to explain the decline in popular connection to political parties. Ironically, the associated causes of this decline are generally regarded as good, notwithstanding that the decline itself is often identified as a crisis. Moreover, analysis of this decline suggests as striking similarity between the consensus model of democracy and the cartel party model of democracy, notwithstanding that the first is often seen as a goal to which democracies should be moving while the second is seen as a threat to democracy itself.
A Psico-oncologia e seus diversos desdobramentos
Authors: DE OLIVEIRA Elisabete , Andrade Maria Clara de Mello
Published: July 2019

O fio condutor deste trabalho é a atuação do psicólogo com pacientes oncológicos no hospital geral. O trabalho trata dos aspectos sobre saúde e doença e a compreensão dos espaços hospitalares, considerando esse espaço como um dos cenários em que os pacientes oncológicos poderão perpassar ao longo do tratamento. Além disso, aborda-se um pouco sobre o câncer e suas modalidades de tratamentos e as diversas repercussões psicológicas que os pacientes oncológicos vivenciam desde o diagnóstico até o tratamento. A partir disso, fica claro a importância da atuação do psicólogo tanto com o paciente e com seus familiares, uma vez que a família pode passar pelos mesmos processos que os pacientes.
Machismo: fruto de esquemas desadaptativos
Authors: Carvalhaes Figueira de Oliveira Silva Giovanna , Jordão Laport Tamires
Published: July 2019

O presente estudo propõe, por meio de uma revisão bibliográfica, a reflexão acerca do machismo, com base na perspectiva teórica da Terapia Cognitivo-Comportamental desenvolvida por Aaron Beck e da Teoria dos Esquemas de Jeffrey Young. Para tanto, relaciona a inclusão de esquemas iniciais desadaptativos à temática, por meio da qual o machismo é compreendido como produto de um processo de perpetuação ideológica transmitida social, cultural e historicamente dentro de ambientes familiares, educacionais, midiáticos e comunitários, considerando a relevância desses grupos quanto a pensamentos e comportamentos aprendidos e reforçados ao longo do tempo.
Preceptoria de Enfermagem em Saúde da Família: definindo sua identidade e relevância para o Sistema Único de Saúde
Authors: Azevedo Gabriela Moiçó , De Souza Ândrea Cardoso , Daher Donizete Vago , Cordeiro Maristela Magalhães dos Santos
Published: July 2019

Objetivos: analisar a importância do preceptor para a formação do residente de enfermagem no Sistema Único de Saúde e conhecer o perfil do profissional preceptor da residência em saúde da família do município do Rio de Janeiro. Método: pesquisa qualitativa do tipo descritiva. Será realizada na rede de atenção básica do município do Rio de Janeiro, onde exista Estratégia Saúde da Família e que seja campo de da residência de enfermagem em saúde da família. Será adotado como critério de inclusão, desenvolver a atividade de preceptor no mesmo cenário por no mínimo o período de um ano e o critério de exclusão será ser preceptor, mas encontrar-se de férias ou licenças durante a pesquisa de campo. Para a coleta de dados, será utilizada a entrevista semiestruturada. Posteriormente, os dados serão tratados por meio da análise temática. A pesquisa foi submetida à apreciação do Comitê de Ética em Pesquisa da Universidade Federal Fluminense e da Secretaria de Saúde do Município do Rio de Janeiro. Resultados esperados: promover uma reflexão do papel do preceptor e de que forma sua prática interfere na formação do residente para o SUS, assim como evidenciar o seu perfil e os métodos pedagógicos que utiliza para auxiliar na formação dos enfermeiros residentes.
Vivência dos profissionais de enfermagem perante a morte neonatal
Authors: Lima Gabriela Rocha , Silva Jannaina Shter Leite Godinho
Published: July 2019

Objetivo: Compreender a percepção dos profissionais de enfermagem frente à morte de recém-nascidos em UTIN. Metodologia: Trata-se de uma pesquisa exploratória, de campo, com metodologia qualitativa. Foram participantes da pesquisa 17 profissionais do quadro de enfermagem de uma UTI neonatal, sendo 05 enfermeiros e 12 técnicos de enfermagem. A coleta de dados foi realizada no mês de setembro de 2018 através de uma entrevista semi-estruturada contendo perguntas abertas e fechadas relacionadas ao tema, após parecer de aprovação n° 2.904.499, CAAE 91426218.1.0000.5290. Resultados: A partir da análise de dados pode-se perceber que os profissionais de enfermagem ao lidarem com o óbito neonatal desenvolvem sentimentos considerados negativos como, por exemplo, tristeza, decepção e frustração. Ao desenvolverem tais sentimentos métodos de enfrentamento são utilizados pelos profissionais para auxiliarem no momento de luto, como o uso da religiosidade, sendo considerada uma estratégia para amenizar o sofrimento do profissional. Conclusão: Conclui-se que é necessário manter um olhar diferenciado para os profissionais de enfermagem que atuam em UTIN, visto que o ambiente é considerado complexo e que desenvolve nos profissionais conflitos emocionais durante sua vivência, o que pode vir a trazer prejuízos para a sua saúde.
Captação da Gestante para Pré-natal precoce
Authors: Serrazina Andrea Fferreira , Silva Geisa Sereno Velloso da
Published: July 2019

O presente trabalho traz um panorama da assistência pré-natal no contexto da atenção básica de saúde e da Estratégia de Saúde da Família (ESF), alertando para a importância do profissional de enfermagem nesse processo para a eficácia da estratégia de saúde, da prevenção de doenças e da diminuição dos índices de mortalidade durante a gravidez. Tem como objetivos identificar as dificuldades do enfermeiro da atenção básica para a captação de gestantes no pré-natal do primeiro trimestre gestacional. Elaborou-se uma pesquisa de campo, de caráter descritivo e abordagem quali-quantitativa sobre as dificuldades vivenciadas pelo enfermeiro na atenção básica de saúde durante a assistência pré-natal, por meio de uma entrevista semi-estruturada realizada com 10 enfermeiros de diferentes unidades de saúde do município de Vassouras/RJ. Verificou-se a necessidade não só de ampliar a captação de gestantes para o recebimento desse cuidado como também a necessidade de aprimorar as estratégias utilizadas nas gestantes captadas. Concluiu-se que os enfermeiros da atenção básica em Vassouras passam por muitas dificuldades na captação de gestantes no primeiro trimestre gestacional, dificuldades inclusive de percepção da própria realidade e de formação e que o quadro não é pior por conta do papel exercido pelas agentes comunitárias de saúde nesse processo.
Os efeitos da laserterapia de baixa potência na cicatrização de lesões por pressão.
Authors: Mendes João Pedro da Motta , Trajano Eduardo Tavares Lima
Published: July 2019

A lesão por pressão (LP) é uma complicação frequente no ambiente intra-hospitalar principalmente em pacientes acamados, levando a consequências como aumento no tempo de internação, infecções, retardo na recuperação e até óbito. A incidência global de LP em pacientes hospitalizados varia de 2,7 a 29%, e esse número pode elevar-se para 33% em pacientes internados em UTI. Uma alternativa no tratamento das LPs é a LBP por suas propriedades terapêuticas para a cicatrização, e uma vez usadas como um tratamento coadjuvante ao convencional apresenta grandes vantagens para o enfermeiro, pois se trata de um tratamento indolor, prático e acarreta na redução de custos. O objetivo dessa revisão é avaliar o reparo tecidual de LP através da LBP, visando inseri-la no contexto hospitalar. Foram publicados artigos nos anos de 1999, 2004, 2003 e entre 2006 e 2018, nas línguas portuguesa e inglesa, que contivessem dados sobre a laserterapia de baixa potência em lesões por pressão. A LBP pode ser usada pelo enfermeiro, desde que o mesmo seja capacitado, e pode ser indicado como coadjuvante no tratamento de LP. É necessário mais estudos na área sobre os parâmetros utilizados na terapia, tais como, dose, potência, comprimento de onda e tempo de irradiação.
Evidências e repercussões do estresse vivenciado pelos enfermeiros da unidade de terapia intensiva
Authors: Ribeiro Wanderson Alves , Coutinho Vanessa Vicente Alves , Morais Maicon Costa de , Souza Douglas Mendes da Silva , Couto Carla de Souza , Oliveira Leandro Sperendio de , Souza João Luiz Ramos de , Mendes José Augustinho
Published: July 2019

Trata-se de um estudo sobre a influência dos estressores que acometem os enfermeiros na assistência aos pacientes internados na Unidade de Terapia Intensiva (UTI). Sabe-se que o estresse tem sido um problema atual por apresentar riscos à estabilidade do equilíbrio no ser humano. Os objetivos foram: identificar as evidências e repercussões que acometem o enfermeiro que atua na UTI e propor estratégias para diminuição dos fatores estressores que acometem o enfermeiro que atua na UTI. Trata-se de uma revisão bibliográfica de abordagem qualitativa. Posterior à leitura reflexiva emergiram três categorias: situações que evidenciam os fatores estressores na UTI; a influência dos fatores estressores na rotina de trabalho e na saúde do profissional enfermeiro e as estratégias utilizadas pelos enfermeiros para minimizar as consequências dos fatores estressores. Conclui-se nesta pesquisa que a UTI é classificada como um setor muito estressante, por estar reservado para pacientes que necessitam de cuidados de alta complexidade. Contudo a pesquisa revelou ainda que a qualidade dos cuidados oferecidos por este profissional não depende apenas de sua habilidade técnica, mas também de seu bem-estar psicológico. Portanto, torna-se essencial realizar novos estudos para identificar fatores estressantes que podem acometer o enfermeiro e identificar suas principais causas e sintomas.Descritores: Enfermagem; Estresse; Unidade de Terapia Intensiva.
Ressignificação da existência e do cotidiano de pessoas que vivem com HIV .
Authors: Gomes Marcia Pereira , Souza Fabiana Barbosa Assumpção de , Gomes Antônio Marcos Tosoli , Silva Girlene Alves da , Barbosa Diogo Jacintho , Silva André Luis Brugger e
Published: July 2019

Estudo descritivo, qualitativo,  parte de um estudo que analisou as condições de vida pessoas vivendo com HIV (PVHIV) e suas implicações para a qualidade de vida. Objetivo descrever e analisar como os sujeitos ressignificam o cotidiano buscando a continuidade e  normalidade da vida  .  Foram 19 entrevistas, com pessoas vivendo com HIV maiores de 18 anos até 70 anos em uso de terapia antirretroviral, e matriculados em um ambulatório de imunologia de um Hospital Universitário. Da análise, emergiram cinco categorias dividas em dois eixos. Neste estudo foi trabalhado o eixo que traduziu  a vida e sua continuidade no contexto de enfrentamento do HIV, abordando a normalidade  e a  busca pela  adaptação a soropositividade. Conclui-se que os sujeitos ressignificam a vivência do cotidiano amparados no  trabalho na rede social de apoio e em elementos que expressam  religiosidade/ espiritualidade e se adaptam  a condição de soropositividade.
Reconhecimento e conduta de cirurgiões-dentistas diante de maus-tratos em crianças e adolescentes
Authors: Santa-Rosa Thalita Thyrza de Almeida , Paula Adrianne Calixto Freire de , Carvalho Bianca Oliveira de , Fróes Danielle Tayrine Celestino , Ferreira Gisele Santos
Published: July 2019

Este estudo objetivou identificar tipos de maus-tratos mais prevalentes incorridos contra crianças e adolescentes, características indicativas de maus-tratos observadas durante atendimento odontológico, além de descrever a conduta do cirurgião-dentista frente a esses casos. Os trabalhos científicos foram selecionados a partir da Biblioteca Virtual de Saúde; 24 artigos atenderam aos critérios pré-definidos. Um manual sobre notificação de maus-tratos infantis do Ministério da Saúde Brasileiro, e texto da Lei 8.069 também foram revisados. Observou-se que maus-tratos contra crianças e adolescentes comumente se manifestam em negligência, abusos físicos, sexuais e psicológicos. Ademais, constatou-se que o cirurgião-dentista pode exercer importante papel na identificação de maus-tratos infanto-juvenis, já que a maioria das lesões físicas oriundas de maus-tratos envolvem cabeça, pescoço e boca. Com base no Estatuto da Criança e Adolescente, o cirurgião-dentista é obrigado a identificar e notificar casos suspeitos de maus-tratos, encaminhando-os para o Conselho Tutelar. No entanto, notou-se inabilidade de cirurgiões-dentistas com relação ao diagnóstico e notificação. A subnotificação de casos de maus-tratos dificulta o dimensionamento epidemiológico do problema e consequente desenvolvimento de programas e ações para seu enfrentamento. Acredita-se que inserir o assunto “maus-tratos infanto-juvenis” nos projetos pedagógicos dos cursos, bem como divulgar práticas de notificação e conduta, contribuirão para erradicação desses maus-tratos.
Uso de vasoconstritores em pacientes portadores de Hipertireoidismo
Authors: Araujo Emanuele Castro de , Silva Thaís Evellyn da , Rocha Marcela Paschoal , Oliveira Leandro Moraes Coelho de
Published: July 2019

Através da anestésica local é possível a realização de grande parte dos procedimentos odontológicos. Os anestésicos locais são substâncias que bloqueiam a condução nervosa, causando a perda temporária da sensibilidade de regiões do corpo. O uso do vasoconstritor traz benefícios para os anestésicos, como a absorção lenta do sal anestésico que resulta em um efeito mais prolongado da anestesia local. Entretanto, em pacientes com determinadas condições sistêmicas, precisam ser adequadamente indicados. É o caso de pacientes portadores de hipertireoidismo, que são mais sensíveis aos vasoconstritores. Foram realizadas buscas em bases de dados Scientific Eletronic Library Online (SciELO), Google Acadêmico e PubMed com os descritores: “Hipertireoidismo”, “vasoconstritor”, “anestésicos locais” e “alterações sistêmicas” além da utilização dos livros de terapêutica medicamentosa e urgências médicas em odontologia, no período de novembro a dezembro de 2018. Uma seleção de 14 documentos serviu de referência bibliográfica para a construção desta revisão de literatura. O objetivo dessa revisão de literatura é abordar o uso de vasoconstritores em pacientes com hipertireoidismo de modo que, o profissional possa intervir com segurança em procedimentos odontológicos que requeiram anestesia local. Foi concluído que, utilizar os vasoconstritores ou não nos procedimentos odontológicos em pacientes com hipertireoidismo, deve ser bem analisado levando em consideração a sua condição sistêmica prévia e atual.
Prevalência da Síndrome de Burnout entre Acadêmicos de Medicina da Universidade de Vassouras – RJ
Authors: De Oliveira Farias Ingrid , Peruzini Giovanna Alves , Almeida Souza Maria Cristina , Vilela Luiz Felipe Furtado , Sayão Capute Ana Claudia
Published: July 2019

A Síndrome de Burnout (SB) é uma condição de sofrimento psíquico ligada ao trabalho que se inicia com elevados e persistentes níveis de estresse, composto pelos fatores multidimensionais: Exaustão emocional, descrença e desrealização profissional. Nos estudantes de medicina, além dos fatores estressores típicos do ensino, há o fato dos mesmos lidarem diretamente com pacientes, podendo propiciar o surgimento das dimensões da síndrome antes mesmo da sua formação. Objetivou-se identificar nos acadêmicos de Medicina da Universidade de Vassouras – RJ a existência da SB. Trata-se de um estudo de campo, observacional, quantitativo analítico e transversal, composto por uma amostra de 440 acadêmicos. Foram aplicados dois questionários, de autopreenchimento e de caráter anônimo, o Maslach Burnout Inventory – Student Survey e o sociodemográfico para identificação de fatores estressores. Para diagnóstico de SB foram calculadas scores para cada dimensão com base na resposta de todos os participantes respeitando-se o desvio padrão, já os parâmetros sociodemográficos e estressores foram relacionados à SB através do Teste Qui-quadrado. A SB foi diagnosticada em 12,5% dos entrevistados. Entretanto não foram encontradas relações estatísticas significativas entre SB e sexo, faixa etária e período da graduação dos entrevistados, bem como com os fatores estressores analisados. Portanto, tal estudo sugere a necessidade de um debate continuado sobre a saúde mental dos profissionais ainda durante sua formação, bem como a importância de novas pesquisas principalmente nessa população que progressivamente vem sendo assolada por comorbidades no âmbito emocional e que ainda pouco se conhece sobre os fatores predisponentes.
Obstrução intestinal causada por Diverticulite de Meckel: Relato de caso
Authors: Esteves Batista Ana Beatriz , Borges Tavares Vieira Richard Raphael , De Sá Silva Jair Jhonatam , Barros Alves Breno , Ferreira de Paula Joaquim , Marques Batista Carlos Augusto
Published: July 2019

O Divertículo de Meckel é a anomalia congênita mais comum do trato gastrointestinal, incidindo em aproximadamente 2% da população em geral. Embora a maioria dos pacientes permaneça assintomática, ele pode se apresentar com uma variedade grande de manifestações clínicas quando surge algum tipo de complicação, geralmente na forma de inflamação, obstrução ou sangramento, tornando amplo o rol de diagnósticos diferenciais. Seu diagnóstico é difícil e ainda permanece como um grande desafio porque a maioria dos exames complementares mostra somente alterações decorrentes das complicações, sem precisão em estabelecer que estas ocorram nesta anomalia, e geralmente ocorre durante a cirurgia. O tratamento nos achados acidentais / incidentais, assim como nos casos manifestados com complicação, é ainda controverso e motivo de dúvidas. No presente estudo descreve-se um caso de diverticulite de Meckel como causa de obstrução do íleo pelo processo inflamatório, onde a técnica de diverticulectomia foi empregada com sucesso no tratamento, garantindo uma boa evolução pós-operatória.
Necrose avascular bilateral da cabeça femoral em paciente com Lúpus eritematoso sistêmico associado à corticoterapia prolongada: Relato de Caso
Authors: Da Silva Robert Alves , Cristina Morais da Silva Amanda , Eduardo Cardoso Carlos
Published: July 2019

A osteonecrose da cabeça femoral é conseqüência de um infarto ósseo isquêmico que pode levar à destruição óssea, com dor e perda de função por conta da morte do tecido.

O lúpus eritematoso sistêmico e o uso prolongado de glicocorticóides apresentam-se como fatores importantes para o desenvolvimento desta patologia.  Assim, o presente trabalho teve como objetivo relatar um caso de osteonecrose bilateral da cabeça femoral com manifestações pouco descritas na literatura e elucidar fatores preditivos para o desenvolvimento desta doença em pacientes com lúpus eritematoso sistêmico associado ao uso prolongado de corticóides. Adicionalmente, pretendeu-se relatar as manifestações clinicas e a terapêutica adotada para resolução deste problema. Pode-se concluir que o diagnóstico precoce desta patologia é de extrema importância e depende da avaliação clínica e de exames de imagens de alta sensibilidade, para que a área acometida possa ser revascularizada e se evite a destruição articular e uma artroplastia total do quadril.