bluuebunny/crossref_metadata_2025 huggingface dataset:
The burden of attempted suicide: The attitude of emergency services workers
Authors: Cuoghi G. , Venuta M. , Mattei G. , Sacchetti A. , Ferrari S.
Published: June 2017

Introduction

The great global burden of suicide requires specific preventive strategies focused on emergency services (ES) workers, providing first aid after attempted suicide.

Objectives

To investigate the approach of ES workers toward attempted suicides, and to assess work-related stress and teamwork attitude as variables likely to influence suicide risk perception.

Methods

A total of 265 ES workers (73 medical doctors, 130 nurses, 62 health and social care workers) from 3 hospitals in the area of Modena (Northern Italy) were involved. In a group setting, titles from local newspapers reporting about suicides were read, and ES workers were asked to fill in 3 psychometric scale questionnaires (SUIATT, MBI and SAQ).

Results

The questionnaires returned were 88 (33%), 47% (n = 42) were filled by women, median age was 40 years. Doctors group had the highest response rate (60%). Burnout levels were intermediate at the Emotional Exhaustion subscale, severe at the Depersonalization subscale and mild at the Professional Efficacy subscale. Eighteen percent recorded a good team perception, 33% had a good perception of their work conditions. SUIATT subscales showed a restrictive attitude toward suicide, regardless of hospital and task.

Discussion

No associations emerged among SUIATT, MBI and SAQ subscales; male sex alone correlated to the SUIATT factor “rationality/mental alteration”, suggesting more “tolerance” of suicidal behaviour.

Conclusions

It is crucial to raise awareness among ES workers on this issue, since those workers considering suicide as “more acceptable” are more likely to recognise its signs.

Disclosure of interest

The authors have not supplied their declaration of competing interest.
The impact of trait emotional intelligence and resilience on suicidal behavior in university students
Authors: Sojer P. , Kainbacher S. , Kemmler G. , Freudenthaler H. , Deisenhammer E.
Published: June 2017

Introduction

Suicidal ideation has repeatedly been reported as a predecessor of suicidal behavior. Several neuropsychological parameters have been associated with suicidal ideation. Emotional intelligence (EI) and resilience, which play an important role in the emergence of psychiatric disorders may also be related with suicidality.

Objectives

The main objective of this study was to investigate the relationship of trait EI and resilience with suicidal ideation. Moreover, we hypothesized that EI and resilience would be correlated with each other and that they were moderating variables between stressful life events and suicidal ideation.

Methods

A total of 277 male and female students without current psychiatric diseases were recruited per online questionnaire asking for lifetime and 4-weeks suicidal ideation and demographic data and containing the Resilience Scale of Wagnild and Young, the Connor Davidson Resilience Scale and, for the measurement of trait EI, the Self-Report Emotional Ability Scale. Additionally, we applied the Social Readjustment Rating Scale to assess stressful life events.

Results

We found significant negative correlations between lifetime and in part 4-weeks suicidal ideation and intrapersonal trait EI as well as resilience. Trait EI and resilience were interrelated. There was no significant moderating effect of trait EI or resilience on the relationship between SRRS score and suicidality.

Conclusion

Assessing EI and resilience as trait factors might be helpful in the prospective identification of suicidal individuals.

Disclosure of interest

The authors have not supplied their declaration of competing interest.
Who Learns More in Interprofessional Mental Health Simulation Training? A Study Comparing Learning Outcomes of Different Professionals who Work in Mental and Physical Health Care Settings
Authors: Valdearenas L. , Attoe C. , Cross S.
Published: June 2017

Introduction

Simulation training has the potential to develop communication and teamwork skills, as well as technical knowledge and competency. Mental health simulation training aims to promote awareness of mental health conditions and to enhance human factors (or non-technical) skills that will enable professionals that work in mental and physical healthcare settings to improve their collaborative and patient-centered clinical practice. This study explored the differences in learning outcomes after a mental health simulation course between different professionals–nursing staff, medical staff, and allied health professionals.

Aims and objectives This project examined the different learning outcomes of human factors, confidence and knowledge, for nursing, medical and allied health professionals following mental health simulation training.

Methods

Course-specific measures of confidence and knowledge were administered pre- and post-training to all participants, in addition to The Human Factors Skills for Healthcare Instrument (HFSHI). A post-course evaluation for with free-text responses to open questions regarding the impact of the training was utilised to collect qualitative data.

Results

With data collection ongoing, preliminary results indicate differences in learning outcome depending on professional background, both in terms of quantitative measures and qualitative findings.

Conclusions

Learning outcomes may differ for different professionals despite receiving the same simulation training focusing on mental and physical health, evidencing the importance of sharing individual learning experiences in simulation using a debrief model.

Disclosure of interest

The authors have not supplied their declaration of competing interest.
Pharmacokinetics, Clinical Efficacy, Safety Profile, and Patient-Reported Outcomes in Patients Receiving Subcutaneous Testosterone Pellets 900 mg for Treatment of Symptoms Associated with Androgen Deficiency
Authors: McMahon Chris G. , Shusterman Neil , Cohen Brian
Published: June 2017

Background

Implantation of testosterone doses of at least 150 to 450 mg (ie, two to six pellets) is common clinical practice despite a lack of prospective data.

Aim

To evaluate pharmacokinetics, clinical efficacy, safety, and patient-reported outcomes in men with androgen deficiency who received implantation of testosterone pellets (900 mg) in an open-label study.

Methods

Men with androgen deficiency (serum testosterone < 300 ng/dL [10.4 nmol/L]) were screened and received 12 testosterone pellets (900 mg). Serum hormone measurements (total and free testosterone, dihydrotestosterone, and estradiol) were obtained on days 1, 5, 8, 15, 29, 57, 85, and 113. All hormones were assayed using validated liquid chromatography and tandem mass spectrometry.

Outcomes

Pharmacokinetics of selected hormones was determined. The patient-reported International Index of Erectile Function (IIEF), Center for Epidemiologic Studies Depression (CES-D), and Androgen Deficiency in the Aging Male (qADAM) questionnaires also were performed. Patients rated their satisfaction on a scale from 1 (very satisfied) to 5 (very dissatisfied). Adverse events were monitored throughout.

Results

Fifteen patients were included (mean age = 54.5 years, SD = 8.6 years). Mean baseline total testosterone concentration was 241.6 ng/dL (SD = 88.8 ng/dL; mean = 8.4 nmol/L, SD = 3.1 nmol/L). Mean testosterone serum concentrations fluctuated during the first 2 weeks (range = 300–1,000 ng/dL, 10.4–34.7 nmol/L) but remained higher than or equal to 300 ng/dL (10.4 nmol/L) through day 113. Concentrations of free testosterone, dihydrotestosterone, and estradiol mirrored that of total testosterone. Male functioning (IIEF score), depression (CES-D total score), and androgen-deficiency symptoms (qADAM total score) improved from baseline. Most patients were “very satisfied” (40.0%) or “quite satisfied” (26.7%) with treatment. Testosterone pellets were well tolerated. Pellet extrusion and polycythemia occurred in one patient each.

Clinical Implications

Implantation of high doses (900 mg) of testosterone pellets are generally well tolerated and could provide clinical benefit for some patients.

Strengths and Limitations

This study provides standardized data for the implantation of 12 testosterone pellets. However, the open-label uncontrolled design of this study and its small and ethnically non-diverse patient population limit the interpretation of these data, particularly the patient-reported outcomes.

Conclusion

Implantation of 12 testosterone pellets (900 mg) was well tolerated and provided adequate and sustained serum testosterone concentrations. Additional randomized controlled trials are needed to confirm efficacy and safety findings.
Male Sexual Function in New Zealand: A Population-Based Cross-Sectional Survey of the Prevalence of Erectile Dysfunction in Men Aged 40–70 Years
Authors: Quilter Merrin , Hodges Lynette , von Hurst Pamela , Borman Barry , Coad Jane
Published: June 2017

Background

Sexual function declines with age and erectile dysfunction (ED) is a common condition worldwide; however, prevalence rates vary markedly between populations and reliable data specific to New Zealand (NZ) are lacking.

Aim

To assess the prevalence of ED in NZ men using a population-based cross-sectional survey.

Methods

Postal questionnaires were sent, according to a modified Dillman method, to a randomly selected age-stratified population-based sample of 2,000 men 40 to 70 years old obtained from the electoral roll. Self-reported erectile function was assessed using the five-item International Index of Erectile Function (IIEF-5) and the single-question self-assessment tool.

Outcomes

The prevalence of ED is presented as crude, age-adjusted to the distribution of the NZ population, and standardized to the World Health Organization World Standard Population (WSP). Associations between sexual function and age were analyzed using χ2 test.

Results

The response rate was 30% (599) and 28% (562) were complete for analysis. The crude prevalence of ED was 42% (22% mild, 10% mild to moderate, 6% moderate, and 4% severe), the age-adjusted prevalence was 38%, and the WSP-adjusted prevalence was 37%. Among men reporting ED, 16% were medically diagnosed and 22% were treated. ED affected 24% of men in their 40s, 38% in their 50s, and 60% in their 60s (P < .001). Age was associated with a significant increase in diagnosed ED (P = .001), treated ED (P = .006), dissatisfaction with current sexual function (P < .001), associated anxiety or depression (P = .023), and a decrease in sexual activity (P < .001).

Clinical Translation

Approximately one in three NZ men 40 to 70 years old might have ED. Although comparable to overseas populations, this prevalence is high.

Strengths and Limitations

This study provides the most reliable, comprehensive, and current information on ED and its risk factors in NZ men. Strengths include the large sample, the use of random selection from a population-based sampling frame, established effective survey methods, and the validated IIEF-5. Limitations include the inability of cross-sectional data to determine causation, non-sampling errors associated with the population-based sampling frame, the low response rate, the inability to assess non-respondents, the possibility of men with ED who were sexually inactive not responding or not completing the IIEF-5, and the inherent inability to rule out recall bias.

Conclusion

ED is a marker of subclinical cardiovascular disease. The high prevalence and low levels of diagnosis and treatment indicate a lost opportunity for timely intervention to delay or prevent the progression toward clinical disease.
A 12-week intervention with protein-enriched foods and drinks improved protein intake but not physical performance of older patients during the first 6 months after hospital release: a randomised controlled trial
Authors: Beelen Janne , de Roos Nicole M. , de Groot Lisette C. P. G. M.
Published: June 2017

During and after hospitalisation, older adults are recommended to consume 1·2–1·5 g of protein/kg body weight per d (g/kg per d) to improve recovery. This randomised controlled trial studied the effectiveness of a 12-week intervention with protein-enriched foods and drinks by following-up seventy-five older patients (mean age: 76·8 (sd 6·9) years) during their first 6 months after hospital discharge. Primary outcomes were protein intake and physical performance (measured with Short Physical Performance Battery (SPPB)). Secondary outcomes for physical recovery were gait speed, chair-rise time, leg-extension strength, hand-grip strength, body weight, nutritional status (Mini Nutritional Assessment), independence in activities of daily living (ADL) and physical activity. The intervention group consumed more protein during the 12-week intervention period compared with the control group (P<0·01): 112 (sd 34) g/d (1·5 (sd 0·6) g/kg per d) v. 78 (sd 18) g/d (1·0 (sd 0·4) g/kg per d). SPPB total score, gait speed, chair-rise time, body weight and nutritional status improved at week 12 compared with baseline (time effect P<0·05), but were not different between groups. Leg-extension strength, hand-grip strength and independence in ADL did not change. In conclusion, protein-enriched products enabled older adults to increase their protein intake to levels that are higher than their required intake. In these older adults with already adequate protein intakes and limited physical activity, protein enrichment did not enhance physical recovery in the first 6 months after hospital discharge.
Identification of Reference Genes for Studying Herbicide Resistance Mechanisms in Japanese Foxtail (Alopecurus japonicus)
Authors: Xu Hongle , Li Jun , Wu Renhai , Su Wangcang , Wu Xibao , Wang Lingyue , Dong Liyao
Published: June 2017

Herbicide-resistant weeds pose a considerable threat to agriculture, but their resistance mechanisms are poorly understood. Differential gene expression analysis of a weed subjected to herbicide treatment is a key step toward more mechanistic studies. Such an analysis, often involving quantitative real-time PCR (qPCR), requires suitable reference genes as internal controls. In this study, we identified optimal reference genes in the noxious weed, Japanese foxtail. This weed has evolved resistance to acetyl-coenzyme A carboxylase (ACCase) inhibitors. We analyzed the stability of eight commonly used candidate reference genes (glyceraldehyde-3-phosphate dehydrogenase [GAPDH]; ubiquitin [UBQ]; capsine phosphatase [CAP]; beta-tubulin [TUB]; eukaryotic initiation factor 4a [EIF4A]; elongation factor-1 alpha [EF1]; 18S ribosomal RNA [18S]; 25S ribosomal RNA [25S]) from root, stem, and leaf tissue of plants that were either resistant or sensitive to ACCase inhibitors, with or without herbicide stress, using qPCR. The results were further ranked and analyzed using geNorm, NormFinder, and BestKeeper software. These analyses identifiedEF1andUBQin roots,EF1,TUB,CAP, and18Sin stems, andEF1,GAPDH, and18Sin leaves as suitable references for qPCR normalization. We have identified a set of reference genes that can be used to study herbicide resistance mechanisms in Japanese foxtail.
Clinical performance of the near-infrared imaging system VistaCam iX Proxi for detection of approximal enamel lesions
Authors: Jablonski-Momeni Anahita , Jablonski Boris , Lippe Nikola
Published: June 2017

Objectives/Aims:

Apart from the visual detection of caries, X-rays can be taken for detection of approximal lesions. The Proxi head of VistaCam iX intraoral camera system uses near-infrared light (NIR) to enable caries detection in approximal surfaces. The aim of this study was to evaluate the performance of the NIR for the detection of approximal enamel lesions by comparison with radiographic findings.

Materials and methods:

One hundred ninety-three approximal surfaces from 18 patients were examined visually and using digital radiographs for presence or absence of enamel lesions. Then digital images of each surface were produced using the near-infrared light. Correlation between methods was assessed using Spearman’s rank correlation coefficient (rs). Agreement between radiographic and NIR findings was calculated using the kappa coefficient. McNemar’s test was used to analyse differences between the radiographic and NIR findings (α=0.05).

Results:

Moderate correlation was found between all detection methods (rs=0.33–0.50, P<0.0001). Agreement between the radiographic and NIR findings was moderate (κ=0.50, 95% CI=0.37–0.62) for the distinction between sound surfaces and enamel caries. No significant differences were found between the findings (P=0.07).

Conclusion:

Radiographs and NIR were found to be comparable for the detection of enamel lesions in permanent teeth.
A study on light transmittance through red protective shields modified with different window films
Authors: Nimmanon Vanida , Pachimsawat Praewpat , Khovidhunkit Siribang-on Pibooniyom , Thanathornwong Bhornsawan , Nimmanon Thirayost
Published: June 2017

Objectives/Aims:

This study aimed to improve effectiveness of red protective shields in filtering unwanted light using window films.

Materials and Methods:

Red protective shields were modified by placing V-Kool (VK), Scotchtint (ST) or Hüper Optik (HP) window films on both sides. Percentage transmittance (%T) of light with a wavelength of 190–990 nm was determined using a double-beam ultraviolet (UV) and visible spectrophotometer.

Results:

In UV light (190–390 nm) and visible light (430–590 nm) ranges, %T in all modified groups and the control was below 2.5%. An increase in %T was observed at the wavelength of 630 nm, when all the modified shields showed superior effectiveness in light filtration over the control. In the infrared spectrum (700–990 nm), %T in the control was constantly high, ranging from 86 to 91%, compared to %T of 2–38% in all the modified groups, with the application of VK on both sides being the most effective group, followed by a combination of VK and HP.

Conclusion:

This study has introduced an economical and simple, yet highly effective, means of enhancing the efficiency of a red plastic protection shield in filtering unwanted infrared light, thereby additionally providing protection for dental personnel from potential ocular damages.
GroEL actively stimulates folding of the endogenous substrate protein PepQ
Authors: Weaver Jeremy , Jiang Mengqiu , Roth Andrew , Puchalla Jason , Zhang Junjie , Rye Hays S.
Published: June 2017

Many essential proteins cannot fold without help from chaperonins, like the GroELS system of Escherichia coli. How chaperonins accelerate protein folding remains controversial. Here we test key predictions of both passive and active models of GroELS-stimulated folding, using the endogenous E. coli metalloprotease PepQ. While GroELS increases the folding rate of PepQ by over 15-fold, we demonstrate that slow spontaneous folding of PepQ is not caused by aggregation. Fluorescence measurements suggest that, when folding inside the GroEL-GroES cavity, PepQ populates conformations not observed during spontaneous folding in free solution. Using cryo-electron microscopy, we show that the GroEL C-termini make physical contact with the PepQ folding intermediate and help retain it deep within the GroEL cavity, resulting in reduced compactness of the PepQ monomer. Our findings strongly support an active model of chaperonin-mediated protein folding, where partial unfolding of misfolded intermediates plays a key role.
Correction: Corrigendum: The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
Authors: Harsman Anke , Oeljeklaus Silke , Wenger Christoph , Huot Jonathan L. , Warscheid Bettina , Schneider André
Published: June 2017

Nature Communications 7: Article number:13707 (2016); Published: 19 December 2016; Updated: 30 June 2017 The original version of this Article contained an error in the gene ID for TimRhom I, cited in the Methods, which specified an unrelated gene. The correct gene ID for TimRhom I is Tb927.9.8260. This has now been corrected in both the PDF and HTML versions of the Article.
Genetic stability of Rift Valley fever virus MP-12 vaccine during serial passages in culture cells
Authors: Lokugamage Nandadeva , Ikegami Tetsuro
Published: June 2017

Rift Valley fever is a mosquito-borne zoonotic disease endemic to Africa, which affects both ruminants and humans. Rift Valley fever causes serious damage to the livestock industry and is also a threat to public health. The Rift Valley fever virus has a segmented negative-stranded RNA genome consisting of Large (L)-segment, Medium (M)-segment, and Small (S)-segment. The live-attenuated MP-12 vaccine is immunogenic in livestock and humans, and is conditionally licensed for veterinary use in the US. The MP-12 strain encodes 23 mutations (nine amino acid substitutions) and is attenuated through a combination of mutations in the L-segment, M-segment, and S-segment. Among them, the M-U795C, M-A3564G, and L-G3104A mutations contribute to viral attenuation through the L-segment and M-segment. The M-U795C, M-A3564G, L-U533C, and L-G3750A mutations are also independently responsible for temperature-sensitive phenotype. We hypothesized that a serial passage of the MP-12 vaccine in culture cells causes reversions of the MP-12 genome. The MP-12 vaccine and recombinant rMP12-ΔNSs16/198 were serially passaged 25 times. Droplet digital polymerase chain reaction analysis revealed that the reversion occurred at L-G3750A during passages of MP-12 in Vero or MRC-5 cells. The reversion also occurred at M-A3564G and L-U533C of rMP12-ΔNSs16/198 in Vero cells. Reversion mutations were not found in MP-12 or the variant, rMP12-TOSNSs, in the brains of mice with encephalitis. This study characterized genetic stability of the MP-12 vaccine and the potential risk of reversion mutation at the L-G3750A temperature-sensitive mutation after excessive viral passages in culture cells.
Correction: Corrigendum: Stk38 Modulates Rbm24 Protein Stability to Regulate Sarcomere Assembly in Cardiomyocytes
Authors: Liu Jing , Kong Xu , Lee Yew Mun , Zhang Meng Kai , Guo Li Yan , Lin Yu , Kwang Lim Teck , Lin Qingsong , Xu Xiu Qin
Published: June 2017

Scientific Reports 7: Article number: 44870; published online: 21 March 2017; updated: 30 June 2017. The original version of this Article contained errors. The original version contained errors in the spelling of the authors Yew Mun Lee, Meng Kai Zhang and Li Yan Guo, which were incorrectly given asLee Yew Mun, Zhang Meng Kai and Guo Li Yan.
Correction: Corrigendum: Electrical Detection of Dengue Biomarker Using Egg Yolk Immunoglobulin as the Biological Recognition Element
Authors: Figueiredo Alessandra , Vieira Nirton C. S. , Santos Juliana F. dos , Janegitz Bruno C. , Aoki Sergio M. , Junior Paulo P. , Lovato Rodrigo L. , Nogueira Maurício L. , Zucolotto Valtencir , Guimarães Francisco E. G.
Published: June 2017

Scientific Reports 5: Article number: 7865; published online: 19 January 2015; updated: 30 June 2017 This Article contains an error in the legend of Figure 3. “(a) Dynamic response of the proposed immunosensor upon the addition of 1 mg.mL−1 NS1 in the measuring cell.” should read: “(a) Dynamic response of the proposed immunosensor upon the addition of 1 μg.
Correction: A facile Pechini sol–gel synthesis of TiO2/Zn2TiO2/ZnO/C nanocomposite: an efficient catalyst for the photocatalytic degradation of Orange G textile dye
Authors: Nassar Mostafa Y. , Ali Ayman A. , Amin Alaa S.
Published: June 2017

Correction for ‘A facile Pechini sol–gel synthesis of TiO2/Zn2TiO2/ZnO/C nanocomposite: an efficient catalyst for the photocatalytic degradation of Orange G textile dye’ by Mostafa Y. Nassar et al., RSC Adv., 2017, 7, 30411–30421.
Ultra-high surface area mesoporous carbons for colossal pre combustion CO2 capture and storage as materials for hydrogen purification
Authors: Cox Michael , Mokaya Robert
Published: June 2017

Mesoporous carbons (with up to 95% of pore volume from mesopores) with surface area and pore volume of ∼4000 m2 g−1 and ∼3.6 cm3 g−1, respectively, are excellent CO2 absorbers under pre combustion conditions and can store 55 mmol g−1 (i.e., 2.42 g g−1) or 930 g l−1 at 25 °C and 50 bar.
Diabetes during Pregnancy: Influence of Body Mass Index on Composite Morbidity
Authors: O'Neil Dudley Amy , Jenner Zachary , Mendez-Figueroa Hector , Ellis Viviana , Chauhan Suneet
Published: June 2017

Objective This study aims to compare composite maternal and neonatal morbidities (MM, NM) among pregnant women with diabetes mellitus whose body mass index (BMI) at delivery was < 30 (group 1), 30.0 to 39.9 (group 2), and ≥ 40 kg/m2 (group 3). We hypothesized that increased BMI class at delivery would be associated with worsening maternal and neonatal outcomes.

Methods This is a retrospective cohort study. MM was defined as: chorioamnionitis, wound infection, eclampsia, diabetic ketoacidosis, hypoglycemia admission, third/fourth degree laceration, and/or death. NM was defined as umbilical arterial pH < 7.0, 5 minute Apgar < 4, respiratory distress syndrome, mechanical ventilation, neonatal sepsis, stillbirth, and/or death. Odds ratios were adjusted for possible confounders.

Results MM was noted in 8, 13, and 24% of groups 1, 2, and 3, respectively, and significantly more common in group 2 versus 1 (adjusted odds ratio [aOR]: 1.66) and group 3 versus 1 (aOR: 3.06). NM was noted in 7, 8, and 15% of each BMI group, respectively, and differed significantly between group 3 vs. 2 (aOR: 1.77).

Conclusions The increased rate of morbidities between the BMI groups is useful to inform diabetic women and highlights the need for further investigation of diabetes and obesity as comorbidities in pregnancy.
61. Jahrestagung der DGKN 2017 mit Richard-Jung-Kolleg in Leipzig: Ein Rückblick und Ausblick
Authors: Hegerl Ulrich , Zierz Stephan , Sander Christian
Published: June 2017

Die 61. Wissenschaftliche Jahrestagung der DGKN fand vom 27.–29. April 2017 an der 1409 gegründeten Universität Leipzig statt unter der gemeinsamen Leitung der Tagungspräsidenten Prof. Ulrich Hegerl, Direktor der Klinik und Poliklinik für Psychiatrie und Psychotherapie am Universitätsklinikum Leipzig, und Prof. Stefan Zierz, Direktor der Neurologischen Klinik und Poliklinik des Universitätsklinikums Halle (Saale). Tagungsort war die in den letzten Jahren aufwendig sanierte Kongresshalle am bekannten Leipziger Zoo, die aufgrund ihrer zentralen Lage und dem bemerkenswerten Mix aus Neo-Barock, Jugendstil, Art Déco und Moderner Architektur einen feierlichen und großzügigen Rahmen für eine abwechslungsreiche Veranstaltung und vielfältigen wissenschaftlichen Austausch bot.
Energy spectrum of oscillations in generalized Sagdeev potential
Authors: Akbari-Moghanjoughi M.
Published: June 2017

In this paper, the full energy spectrum of nonlinear oscillations, known as the cnoidal waves, is studied in the framework of small-amplitude Korteweg de Vries and modified Korteweg de Vries (mKdV) theories based on the pseudoparticle motion in Helmholtz and Duffing potentials by employing the newly introduced pseudoenergy concept. The pseudoenergy dependence of various cnoidal oscillation parameters is then studied, and it is shown that superposition of cnoidal waves leads to familiar beating and Lissajous profiles. One of the most important aspects of the nonlinear oscillation is found to be the frequency dependence of the oscillation amplitude which mainly characterizes the nature of oscillations. It is shown that the developed method can be used to study the spectrum of oscillations and shock waves in the fully nonlinear Sagdeev pseudopotential and to directly calculate many dynamic parameters of the given nonlinear system. Current research may be helpful in understanding of basic excitations and interaction of nonlinear oscillation in various hydrodynamic systems including plasmas. It is also shown that nonlinear excitations in a hydrodynamic fluid can be effectively investigated by close inspection of shock waves which contain the full nonlinear spectrum of dynamical systems.
Treating Late Life Depression
Authors: Thompson Larry W. , Dick-Siskin Leah , Coon David W. , Powers David V. , Gallagher-Thompson Dolores
Published: June 2017

This workbook is designed for your use as you work together with a therapist to overcome your depression. It contains information on cognitive-behavioral therapy (CBT) and how it can help to reduce the symptoms of depression. Each chapter corresponds to a treatment module, and case examples are presented throughout and provide excellent illustrations of the main points, as well as summary questions, home assignments, and in-session exercises, worksheets, and forms. It explores how your thoughts, emotions, and behaviors work to maintain your depression and how to challenge and modify them in order to improve your mood and quality of life.
Effectiveness and Safety of an Extended ICU Visitation Model for Delirium Prevention: A Before and After Study*
Authors: Rosa Regis Goulart , Tonietto Tulio Frederico , da Silva Daiana Barbosa , Gutierres Franciele Aparecida , Ascoli Aline Maria , Madeira Laura Cordeiro , Rutzen William , Falavigna Maicon , Robinson Caroline Cabral , Salluh Jorge Ibrain , Cavalcanti Alexandre Biasi , Azevedo Luciano Cesar , Cremonese Rafael Viegas , Haack Tarissa Ribeiro , Eugênio Cláudia Severgnini , Dornelles Aline , Bessel Marina , Teles José Mario Meira , Skrobik Yoanna , Teixeira Cassiano
Published: June 2017

Objectives:

To evaluate the effect of an extended visitation model compared with a restricted visitation model on the occurrence of delirium among ICU patients.

Design:

Prospective single-center before and after study.

Setting:

Thirty-one–bed medical-surgical ICU.

Patients:

All patients greater than or equal to 18 years old with expected length of stay greater than or equal to 24 hours consecutively admitted to the ICU from May 2015 to November 2015.

Interventions:

Change of visitation policy from a restricted visitation model (4.5 hr/d) to an extended visitation model (12 hr/d).

Measurements and Main Results:

Two hundred eighty-six patients were enrolled (141 restricted visitation model, 145 extended visitation model). The primary outcome was the cumulative incidence of delirium, assessed bid using the confusion assessment method for the ICU. Predefined secondary outcomes included duration of delirium/coma; any ICU-acquired infection; ICU-acquired bloodstream infection, pneumonia, and urinary tract infection; all-cause ICU mortality; and length of ICU stay. The median duration of visits increased from 133 minutes (interquartile range, 97.7–162.0) in restricted visitation model to 245 minutes (interquartile range, 175.0–272.0) in extended visitation model (p < 0.001). Fourteen patients (9.6%) developed delirium in extended visitation model compared with 29 (20.5%) in restricted visitation model (adjusted relative risk, 0.50; 95% CI, 0.26–0.95). In comparison with restricted visitation model patients, extended visitation model patients had shorter length of delirium/coma (1.5 d [interquartile range, 1.0–3.0] vs 3.0 d [interquartile range, 2.5–5.0]; p = 0.03) and ICU stay (3.0 d [interquartile range, 2.0–4.0] vs 4.0 d [interquartile range, 2.0–6.0]; p = 0.04). The rate of ICU-acquired infections and all-cause ICU mortality did not differ significantly between the two study groups.

Conclusions:

In this medical-surgical ICU, an extended visitation model was associated with reduced occurrence of delirium and shorter length of delirium/coma and ICU stay.
Papilloschisis: A Case Report
Authors: Osman Lina , Deol Sundeep , Mather Diana , Mukherji Subhanjan
Published: June 2017

We report a case of papilloschisis, where the schisis is noted within the optic nerve tissue with no associated disc pit. This has not been reported in the literature to the best of our knowledge.
The eardrums move when the eyes move: A multisensory effect on the mechanics of hearing
Authors: Gruters K. G. , Murphy D. L. K. , Jenson Cole D. , Smith D. W. , Shera C. A. , Groh J. M.
Published: June 2017

Interactions between sensory pathways such as the visual and auditory systems are known to occur in the brain, but where theyfirstoccur is uncertain. Here we show a novel multimodal interaction evident at the eardrum. Ear canal microphone measurements in humans (n=19 ears in 16 subjects) and monkeys (n=5 ears in 3 subjects) performing a saccadic eye movement task to visual targets indicated that the eardrum moves in conjunction with the eye movement. The eardrum motion was oscillatory and began as early as 10 ms before saccade onset in humans or with saccade onset in monkeys. These eardrum movements, which we dub Eye Movement Related Eardrum Oscillations (EMREOs), occurred in the absence of a sound stimulus. The EMREOs’ amplitude and phase depended on the direction and horizontal amplitude of the saccade. They lasted throughout the saccade and well into subsequent periods of steady fixation. We discuss the possibility that the mechanisms underlying EMREOs create eye movement-related binaural cues that may aid the brain in evaluating the relationship between visual and auditory stimulus locations as the eyes move.

SIGNIFICANCE STATEMENT

The peripheral hearing system contains several motor mechanisms that allow the brain to modify the auditory transduction process. Movements or tensioning of either the middle-ear muscles or the outer hair cells modify eardrum motion, producing sounds that can be detected by a microphone placed in the ear canal (e.g. as otoacoustic emissions). Here, we report a novel form of eardrum motion produced by the brain via these systems -- oscillations synchronized with and covarying with the direction and amplitude of saccades. These observations suggest that a vision-related process modulates the first stage of hearing. In particular, these eye-movement related eardrum oscillations may help the brain connect sights and sounds despite changes in the spatial relationship between the eyes and the ears.
A mannitol/sorbitol receptor stimulates dietary intake inTribolium castaneum
Authors: Takada Tomoyuki , Sato Ryoichi , Kikuta Shingo
Published: June 2017

Perception of chemical stimuli by insects aids in accepting or rejecting food. Gustatory receptors (Grs) regulating external signals in chemosensory organs have been found in many insects.Tribolium castaneum, a major pest of stored products, possesses over 200Grgenes. An expanded repertoire ofGrgenes appears to be required for diet recognition in generalist feeders; however, it remains unclear whetherT. castaneumrecognizes a suite of chemicals common to many products or whether it is attracted to specific chemicals, and whether its Grs are involved in its feeding behavior. It is difficult to determine the food preference ofT. castaneumbased on its dietary intake due to a lack of appropriate methodology. This study established a novel dietary intake estimation method using gypsum, designated the TribUTE (TriboliumUrges To Eat) assay.T. castaneumadults were fed gypsum block without added organic compounds. Sugar preference was determined by adding sweeteners and measuring the amount of gypsum in the excreta. Mannitol was the strongest attractant ofT. castaneumdietary intake; in addition, TcGr20 was responsible for mannitol and sorbitol responses inXenopusoocyte expression, but did not respond to any other non-volatile compounds tested. The EC50values of TcGr20 for mannitol and sorbitol were 72.6 mM and 90.6 mM, respectively, suggesting that TcGr20 is a feasible receptor for the recognition of mannitol in lower concentrations.TcGr20was expressed in the antennae, where the perception of mannitol would occur. We examined whetherTcGr20was involved in mannitol recognition using RNAi and the TribUTE assay. The amounts of excreta inTcGr20dsRNA-injected adults decreased significantly despite the presence of mannitol, compared to that of the control adults. Taken together, our results suggest thatT. castaneumadults recognized mannitol/sorbitol using TcGr20 receptors, thereby facilitating their dietary intake.

Abbreviation

ORF

open reading frame

RT

reverse transcription

RNAi

RNA interference

dsRNA

double strand RNA

cRNA

capped RNA

MBS

modified Barth’s saline

CBB

Coomassie brilliant blue

Gr

gustatory receptor
GIGGLE: a search engine for large-scale integrated genome analysis
Authors: Layer Ryan M. , Pedersen Brent S. , DiSera Tonya , Marth Gabor T. , Gertz Jason , Quinlan Aaron R.
Published: June 2017

GIGGLE is a genomics search engine that identifies and ranks the significance of shared genomic loci between query features and thousands of genome interval files. GIGGLE scales to billions of intervals, is faster (+1,000X) than existing methods, and its speed extends the accessibility and utility of resources such as ENCODE, Roadmap Epigenomics, and GTEX by facilitating data integration and hypothesis generation. GIGGLE is available athttps://github.com/ryanlayer/giggle.
Aspects of corporate wellness programs: comparisons of customer satisfaction
Authors: Smith Alan David , Damron Terry , Melton Amye
Published: June 2017

Purpose

With the passage of the Affordable Health Care Act in the USA, many companies are investing in corporate wellness programs as a way to reduce healthcare costs and increase productivity of their workforces. Increasing healthcare expenditures and the pandemic of obesity and chronic diseases are driving forces to the development and implementation of workplace wellness programs across the globe. Companies expect to experience a return on their investment through lower healthcare costs and increased productivity. The paper aims to discuss these issues.

Design/methodology/approach

In this study, 109 business professionals were surveyed (primarily almost equally divided between Russian and Americans citizens) to examine their health-promoting and health risk behaviors. Demographics were compared in an effort to identify the key differences in order to pinpoint development opportunities to increase efficiencies among target populations.

Findings

According to the results, nationality was related to certain differences in health-promoting behaviors, participation rates and frequency of wellness programs offered by employers. No differences were found among different age groups. The results indicated that not even a single wellness program design is appropriate for all companies or even one company across all locations.

Research limitations/implications

Although there were no general conclusions have been drawn nor have the influencing factors for the different behaviors of the various target groups been adequately examined in this exploratory study, there were baselines developed for future research.

Originality/value

Few empirical studies exists that measure the perceived value of corporate wellness programs, especially among different cultural settings. In effect, wellness programs need to be developed specifically for the target population, with considerations to perceived value differences.
Measuring the comparative performance of branches of a credit union for internal benchmarking
Authors: Joo Seong-Jong , Stoeberl Philipp A. , Liao Kun , Ke Ke
Published: June 2017

Purpose

The purpose of this paper is to identify the efficiency scores of branches and districts, the sources of inefficiency for branches and projections of variables for inefficient branches. It measures the comparative performance of branches of a credit union for internal benchmarking.

Design/methodology/approach

The paper measures the performance of 35 branches of a credit union in the USA and suggests managerial insights. Data envelopment analysis is used for measuring the relative performance of the branches and districts of the credit union. The paper also compares performance differences among the districts using non-parametric statistical analyses.

Findings

Parts of the findings indicated that branches should focus on cost containment by reducing operating expenses and increasing their loan balances. In addition, districts were operated in different market conditions, which were evidenced by scale efficiency. The major contributions of the study are filling the void of benchmarking studies at a branch level in the credit union sector, suggesting a framework for internal benchmarking, and providing practical insights to managers of credit unions. The framework of this study can be applied to similar financial institutions with minor revisions.

Research limitations/implications

The limitation of this study is found in the use of cross-sectional data, which is mainly due to the sensitivity of information disclosure of the credit union.

Practical implications

The paper includes implications for the development of benchmarking studies at a branch level in the credit union sector.

Originality/value

This paper fulfills an identified need to study how to identify source of inefficiencies so as to further improve the efficiency of branches.
Selection and evaluation of third party logistics service provider (3PLSP) by using an interpretive ranking process (IRP)
Authors: Narkhede Balkrishna Eknath , Raut Rakesh , Gardas Bhaskar , Luong Huynh Trung , Jha Manoj
Published: June 2017

Purpose

The concept of third-party logistics service provider (3PLSP) has been considered as an essential organizational philosophy to achieve profits. The purpose of this paper is to analyze and examine the contextual relationship among the critical success factors (CSF) of 3PLSPs practices in the cement manufacturing industry.

Design/methodology/approach

In this paper, the total 20 critical selection criteria with nine processes for the 3PLSPs, of an Indian cement manufacturing industry have been identified through an exhaustive literature review and opinions of the experts i.e. academics and industries. Interpretive ranking process (IRP) methodology has been presented to find out the rankings of the individual criteria and the mutual influence in the selection process.

Findings

The proposed model establishes the dominance of relationship among identified criteria, which plays a vital role in the 3PLSPs selection process which are experience in similar product, quality of management, information technology capacity, flexibility in operation and delivery, compatibility with the users.

Research limitations/implications

An empirical research approach has not been used to collect primary data to rank different criteria for effective 3PLSPs implementation in the Industry. In this paper, an example of Indian cement industry is presented to show the real world applicability of the proposed model.

Originality/value

This model would help a decision maker to decide the issues related to a selection of 3PLSPs. The third party service provider comprises the use of external companies who controls and delivers logistic activities. The paper discusses very practical issues in an analytical manner, using the case base method.
Benchmarking between vegetable suppliers in Greece
Authors: Souliotis Andreas , Giazitzi Katerina , Boskou George
Published: June 2017

Purpose

The purpose of this paper is to develop and implement benchmarking methods on food safety and hygiene between suppliers of fruits and vegetables, regardless the food safety management systems they implement.

Design/methodology/approach

A tailor made questionnaire was prepared of 64 questions, divided into ten sectors regarding hygiene and food safety. The suppliers were selected from the inventory of a large chain of retail stores. The audits were performed by a food safety expert on the site of the company. Totally, 72 audits were conducted in several geographic regions of Greece. The data collected was statistically analyzed for benchmarking with technical, geographical or financial criteria.

Findings

The large size companies have a level from satisfactory to very satisfactory in the transport and need improvement on their packaging materials. Improvement in procedures of cleaning and disinfection is required by companies which are in the region of Attica and the Peloponnese.

Originality/value

The proposed methodology and analysis can be used to benchmark groups of food companies with common commercial profile in order to prioritize both the frequency of audits and the importance of interventions and preventive measures.
Mapping out Arab international book fairs
Authors: Al-Aufi Ali Saif , Al-Harrasi Nabhan , Al-Balushi Shahid , Al-Azri Hamed
Published: June 2017

Purpose

The purpose of this study is to investigate the status, challenges and impacts of the Arab international book fairs, with particular focus on the Muscat Book Fair. This study proposes a framework to assist in the design and organisation of future Arab book fairs.

Design/methodology/approach

The study used a variety of methods to obtain data, including questionnaires, site visits (both regional and international), observations and interviews. A literature review was also undertaken which helped determine major worldwide issues related to aspects of book fairs and the publishing industry, focusing on Arab book fairs.

Findings

Arab international book fairs remain relatively traditional, however, there are several examples of innovative improvements in some states. Reading habits and literacy trends were found to be influenced by dominant socio-cultural factors, emphasising religion and children’s literature. This seems to have a reverse effect on the publishing industry. Results also revealed a number of disadvantages related to economic downturns and political instability. Despite continuous expansion, Arab book fairs still suffer from various obstacles which affect the publishing industry’s growth. There are other obstacles that they face which are directly associated with distribution and marketing as well as violations of intellectual property laws.

Practical implications

This study proposes a framework for future improvement of the Muscat Book Fair. It discusses the engagement of local cultural institutions, non-profit community and academic organisations, as well as private sector organisations. These will leverage value and help keep abreast of international developments in book fairs/publishing. It is hoped that the proposed framework will be beneficial to those running book fairs at a regional level, and to countries with developing economies.

Originality/value

There have been no previous empirical studies investigating book fairs in the Arab states. This study adds to the currently scarce body of literature related to book fairs and the publishing industry.