bluuebunny/crossref_metadata_2025 huggingface dataset:
STOCK MARKETS OF RUSSIA AND AMERICAN: ANALYSIS, PROBLEMS AND INVESTMENT PROSPECTS
Authors:   Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia, Melekhin Vyacheslav D. , Bozhikova Tatyana P. ,   Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia, Ryazanov Roman M. ,   Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia
Published: December 2023

The stock market is an excellent tool not only for preserving, but also for increasing your capital. In conditions of geopolitical tension, it is extremely important for an investor to monitor all trends and be aware of the risks of investing in the financial assets of a particular state. This article is a study of the stock markets of Russia and the United States with the aim of analyzing, identifying problems and assessing investment prospects. The authors conduct a comprehensive analysis of two stock exchanges, considering various factors and the degree of their influence on the markets. The article uses methods of comparative analysis, statistical calculations, and logical inference to determine the main trends and patterns, as well as identify problems faced by investors. During the study, the authors discovered a number of differences between the domestic stock market and the American one. For example, the US stock market is more developed and attracts more investment than the Russian one. The Russian stock market suffers to a greater extent from problems with stability and unpredictability, which are caused by periodic geopolitical tensions, as well as strong fluctuations in the exchange rate. The article also examines the prospects for investing in securities of Russian and American companies. The authors point to the significant potential of the Russian market due to its large number of undervalued stocks and opportunities for long-term investment. However, they also list a number of measures and conditions that the domestic market needs to attract more investors and achieve sustainable growth. During the article, the authors offer recommendations for investing in the stock markets of Russia and America. The authors encourage investors to evaluate the risks and rewards of each market and consider their individual investment objectives and opportunities. They also emphasize the need for awareness and continuous assessment of market conditions to make informed investment decisions. This work represents a valuable contribution to the understanding of these stock exchanges and can serve as a basis for further research and the development of investment strategies.
MINIMIZING MANAGEMENT COSTS – THERE IS NO ALTERNATIVE FOR ECONOMIC GROWTH AND LIVING STANDARDS TODAY
Authors:   All-Russian Research Institute of Certification, Moscow, Russia, Versan Vilya G.
Published: December 2023

The more than thirty-year period of ultra-liberal trampling on the ground of our economy is largely due to the poor quality of management. Representatives of the scientific and technical community and business have talked and are talking about this a lot. My colleagues and I wrote about this. Our reformers themselves have repeatedly recognized the low quality of governance. But they did nothing to correct the situation. They always denied their guilt in this, with their characteristic self-confidence. They got the wrong people – for them he is the main culprit. They are offended by him and leave the country.
EVALUATION OF THE BROKERAGE SERVICES MARKET BASED ON MODERN MARKETING RESEARCH TECHNOLOGIES
Authors:   Federal State Budgetary Educational Institution of Higher Education «Donetsk National University of Economics and Trade named after Mikhail Tugan-Baranovsky», Donetsk, Kozlov Vladimir S.
Published: December 2023

It was determined on the basis of marketing research that according to official information of the customs authorities in 2017, customs procedures for customs transit in electronic form on the principle of a “single window” became mandatory and as a result of customs operations, 4,4 million units of customs declarations were issued by the customs authorities of the Russian Federation, which significantly increased the level of revenues to the state budget from customs duties and payments. The estimation of the volume of customs declaration processing in the Russian Federation, units for 2017-2022 is presented. It is assumed that in the period up to 2028, according to experts in the customs services market, there will be a certain transition period in the activities of customs brokers, during which the customs market will undergo a serious path of adaptation to tax and customs legislation and new or existing requirements for customs legislation will be introduced or improved (2019-2021), which indicates that outsourcing in the customs activity will be within the expected value of 1-2%, according to forecasts. It is indicated that in the period 2021-2028. it is planned to conduct and organize a post-adaptation period, during which it is expected to reduce outsourcing operations in a shared ratio, taking into account the statistical error with an annual rate of 5-7%. Summarizing the opinions of experts and the forecast values of the development of the customs services market and the activities of customs brokers, the trends in the development of the activities of customs brokers are determined. Customs brokers will always be in demand also because the demand for competent and highly specialized specialists is increasing, such specialists are being trained by educational organizations of higher education, the list of their professional competencies is being improved, requirements are increasing and indicators for checking the KPIs of customs brokers are expanding.
Inteligencia artificial y educación semipresencial. Reflexiones sobre la universidad digital a partir de dos experiencias en la UAM Azcapotzalco de México
Authors: Lozano Carrillo Óscar , Ramos García Jesús Manuel , Garibay Suárez Alfredo
Published: December 2023

La creciente digitalización ha impactado fuertemente a la educación superior universitaria, ya que las herramientas tecnológicas para la enseñanza, la investigación y la difusión de la cultura se armonizan con las competencias cada vez más exigentes para la juventud en el contexto escolar, cotidiano y laboral. Reflexionar sobre la digitalización universitaria constituye una responsabilidad importante para todas las instituciones de educación superior y los gobiernos de México y la región latinoamericana. Por ello, en este artículo, se realiza una reflexión sobre dos casos de éxito en la UAM-Azcapotzalco: un programa de educación semipresencial en materia de docencia, y un proyecto de inteligencia artificial para la gestión, en materia de investigación.
Importance of Roboticsin Daily Life Schedule
Authors: Sharma Pramod , Saini Rajkumar , Choudhary Dayanand , Kumawat Manish
Published: December 2023

Robotics has witnеssеd rеmarkablе advancements in rеcеnt yеars, pushing thе boundaries of what machinеs can achiеvе. This abstract providеs an ovеrviеw of thе challеngеs that thе fiеld of robotics facеs and thе significant advancements that havе bееn madе to ovеrcomе thеsе hurdlеs. Challеngеs includе complеx pеrcеption, dеxtеrity, human-robot intеraction, and еthical considеrations. On thе othеr hand, advancements encompass innovations in machinе lеarning, computеr vision, sеnsor tеchnology, and thе intеgration of AI. Thе continuous interplay bеtwееn challenges and advancements in robotics is rеshaping industriеs, from manufacturing to hеalthcarе, and holds thе potеntial to rеdеfinе thе futurе of human-robot collaboration. This papеr dеlvеs into thеsе topics, providing insights into thе dynamic landscapе of robotics and its еvolving rolе in our sociеty.
Media ownership and its influence on political reporting
Authors: Agarwal Lokesh , Priti  , Jaiswal Shrijal , Kumar Sachin
Published: December 2023

In this study, the concept of media ownership and its significant impact on political reporting is discussed. In media ownership, individuals, companies, and government agencies control and own media outlets. As a result of a concentration of media ownership in the hands of a few companies, they are able to shape public opinion significantly. This study emphasises the crucial part media ownership plays in the larger political landscape and the significance of media variety for a healthy and educated democratic society. By choosing, crafting, and presenting just certain stories, media proprietors can bring bias into reporting. Whether deliberate or accidental, this bias has the potential to skew public perception and influence political outcomes like elections and policy choices. This study emphasises the crucial part that media ownership plays in the larger political landscape and the significance of media variety for a healthy and informed democratic society
FEATURES OF THE FORMATION OF THE CIVIL DEFENSE OF UKRAINE IN THE CONTEXT OF THE SECURITY FUNCTION
Authors:   Institute of Public Administration and Research in Civil Protection, Kyiv, Ukraine, Andriienko Mykola , Haman Petro ,   Institute of Public Administration and Research in Civil Protection, Kyiv, Ukraine, Gordeieiv Pavlo ,   Institute of Public Administration and Research in Civil Protection, Kyiv, Ukraine
Published: December 2023

At the current stage, the globalization of environmental problems, the growth of social and economic consequences of emergency situations, the expansion of terrorist activities and increased attention to the safety of the population in European society have caused the transformation of the concept of national security in the field of civil protection. Emergency situations of various nature in the form of natural disasters, man-made disasters, acts of terrorism and sabotage, regional conflicts with the use of military force occupy not the last place among the threats to ensuring sustainable development in Ukraine. Ignoring them in modern conditions calls into question not only economic growth and social well-being, but also the provision of the country's national security. Considering the fact that the modern world remains vulnerable to emergencies of various natures, which arise naturally and are created artificially, research in the field of civil defense for the purpose of ensuring national security will not lose its relevance in the future. The purpose of the article is to study the peculiarities of the formation of the civil defense of Ukraine in the context of the security function. The article analyzes the formation of civil protection, defines security functions. A mega-theory of managing the civil defense system in the context of state security has been developed, taking into account hypotheses, calculations and the real state of affairs regarding the impact of turbulent environments on society. Based on the use of methods and models of project-oriented management, an information model of the organizational structure of the management of the civil defense system of Ukraine was developed based on the "centralization-decentralization" criterion. All this requires a process of research and decision-making on the formation of the organizational structure of management in order to improve the system of civil protection, as a function of the state aimed at protecting the population, territory, natural environment and property from emergency situations by preventing and eliminating their consequences and providing assistance to the victims.
LEGAL EDUCATION AS AN OBJECT OF ADMINISTRATIVE AND LEGAL REGULATION
Authors:   Institute of Law and Public Relations, Open International University of Human Development ", Orlovska Iryna ,   Ukraine",   , Kyiv, Ukraine
Published: December 2023

The article examines the issues of administrative and legal regulation of legal education, in particular, its practical aspects. The authors note that quality education is a prerequisite for the implementation of democratic principles of state governance and social, political, economic, spiritual and cultural development of society. The authors emphasise that a special role in ensuring good public administration is played by professionals with legal education. Therefore, from year to year, legal education occupires top positions among university entrants. To study the peculiarities of administrative and legal regulation of legal education, the authors analyse previous scientific research in this area, explanations in the relevant acts regarding the regulation of major legal specialties, and attempts by legislators to regulate the concept of "legal education". It is established that in Ukraine, the Constitution enshrines the right of citizens to receive education, as well as the State's obligations to ensure it, which are primarily realised through lawmaking. In Ukraine, one can obtain a law degree in the following specialities: 081 Law and 293 International Law. The procedure for obtaining a legal degree is regulated by the state, which thus influences the regulation of legal education for students and creates conditions for ensuring quality education in the country. However, the quality of legal education depends not only on public administration institutions, but also on the management of the educational institution. That is why the process of obtaining a quality legal education is a complex phenomenon that requires the contribution of all parties in the system "state - educational institution - person wishing to obtain legal education". Having analysed the existing legal provisions, at this stage of development of our legal system, the authors consider the system of legal acts in the field of education, including legal education, to be satisfactory. However, the authors note that today the administrative and legal regulation of legal education is taking place in extremely difficult conditions of external aggression, martial law, economic and humanitarian crisis caused by Russia's full-scale war against Ukraine.
THE MAIN ASPECTS OF JUSTICE IN UKRAINE
Authors:   Open International University of Human Developmеnt «Ukraine», Shapochka Oleksandr
Published: December 2023

The article analyses the main aspects of justice in Ukraine. It is noted that the justice system is a crucial element of the national legal protection mechanism, and the level of its legitimacy is an indicator of the effectiveness of its functioning through the prism of Article 3 of the Constitution of Ukraine, which states that the establishment and ensuring of human rights and freedoms is the main duty of the State and determines the content and focus of its activities, in particular, ensuring the right to a fair trial for everyone. The article analyses the main aspects of the Decision of the National Security and Defence Council of Ukraine (NSDC) "On Accelerating Judicial Reform and Overcoming Corruption in the Justice System" No.359/2023 dated 23 June 2023, which marks a strategic step in improving the judicial system of Ukraine. In general, this NSDC Decision reflects Ukraine's aspirations for a fair and independent judiciary, which is a key factor in building a just and lawful society. The term justice is defined − is the principle and system of ensuring the observance of law and justice in society through the consideration of court cases and the issuance of decisions on the basis of established laws and norms of law. The article presents the term "justice" in three main meanings of its interpretation. The author identifies the main components of justice in Ukraine, which are designed to ensure the observance of justice, rights and freedoms of citizens. They are based on the principles of democracy and the rule of law.
Critical Discourse Analysis on the Podcast “Putusan MK: Palu Hakim Patah Berkeping"
Authors: Kurniansyah Rafli Akram , Siregar Rachmi Kurnia
Published: December 2023

The existence Constitutional Court decision regarding the requirements for registering Candidates for President and Vice President Republic of Indonesia has caused a number of controversies in society today. An issue Gibran Rakabuming Raka, Mayor of Surakarta, will take part in the 2024 Presidential Election as Candidate Vice President. However, the age threshold criterian 40 years is an obstacle for the son of President Joko Widodo. So, this was done by suing the Constitutional Court to revise the criteria for presidential election participants, especially regarding minimum age. This raises big questions regarding President Jokowi's relationship with the political dynasty, which made the controversial phenomenon increasingly discussed by the media. For this reason, this research uses a qualitative descriptive research method using a critical discourse analysis approach modeled by Teun A.Van Dijk analyzing text in Najwa Shihab's podcast with the title "Putusan MK: Palu Hakim Patah Berkeping" with a duration of 27 minutes 36 seconds which was uploaded on October 18, 2023, on Najwa Shihab's Youtube channel. The podcast discussion criticized the judge's decision which was interfered with by political interests. The results of the research show that democratic order is now increasingly shifting to the power held by political elites who are in power so that power they have can change laws and slowly break the spirit of democracy in Indonesia
Fonologi Kata Pinjaman Tamil dalam Bahasa Melayu Berdasarkan Teori Optimaliti
Authors: Krishnasamy Thamaraselvi , Syed Jaafar Sharifah Raihan
Published: December 2023

Kajian ini bertujuan untuk menjelaskan perubahan fonologi kata pinjaman Tamil yang diserap masuk ke dalam bahasa Melayu. Kata pinjaman Tamil perlu menjalani perubahan fonologi demi untuk mematuhi sistem nahu bahasa Melayu. Oleh sebab bahasa Tamil dan bahasa Melayu mempunyai nahu yang berbeza, maka timbul persoalan, apakah perkataan bahasa Tamil yang telah dipinjam dan bagaimanakah perkataan Tamil tersebut menghasilkan bentuk yang baharu untuk disesuaikan dengan sistem bahasa Melayu? Oleh itu, kajian ini dilakukan untuk mengenal pasti kata pinjaman Tamil yang mengalami perubahan fonologi apabila diserap masuk ke dalam bahasa Melayu, dan mengkategorikan serta menjelaskan secara teoretis jenis adaptasi yang berlaku berdasarkan perubahan fonologi kata pinjaman Tamil. Kajian ini menggunakan data sekunder yang diperoleh daripada Noriah dan Selvarani (2015). Sejumlah 381 perkataan Tamil telah dikenal pasti digunakan dalam bahasa Melayu. Hasil analisis tatatingkat kekangan dalam teori Optimaliti menunjukkan kata pinjaman Tamil dalam bahasa Melayu melibatkan perubahan pada peringkat struktur suku kata, iaitu degeminasi, pemendekan vokal dan pengguguran suku kata.
Unsur Penanda Wacana dalam Teks Ucapan Belanjawan 2019
Authors: Abd Hamid Muhammad Faizul , Abdul Jabar Mohd Azidan , Abdullah Muhammad Alif Redzuan
Published: December 2023

Teks ucapan dianggap sebagai wacana yang sempurna dengan wujudnya penghubung yang bertunjangkan semantik antara komponen teks. Pertalian yang dikenali sebagai penanda wacana ini membolehkan ayat-ayat dalam perenggan disusun dengan baik sehingga urutan maklumat menjadi lancar dan mudah difahami. Oleh itu, makalah ini bertujuan untuk mencungkil pelbagai unsur penanda wacana dan rasional penggunaannya dalam teks ucapan Belanjawan 2019 sebagai salah satu cara untuk mengalirkan mesej penting kepada khalayak ramai. Teks ucapan ini merupakan strategi belanjawan parti gabungan Pakatan Harapan yang pertama apabila memegang tampuk pemerintahan kerajaan Malaysia yang baharu. Penyelidikan ini merupakan kajian berbentuk deskriptif yang menggunakan kaedah kualitatif. Kerangka pemikiran adverba anafora Asmah (2008) dan teori Nahu Fungsian (Halliday & Matthiessen, 2014) telah dijadikan pegangan dalam proses penyelidikan. Berdasarkan hasil kajian, terdapat pelbagai jenis unsur penanda wacana yang digunakan oleh pengucap dalam teks ucapan Belanjawan 2019. Penghubung penambahan, adverba tujuan dan adverba manfaat dilihat sebagai tiga unsur penanda wacana yang kerap digunakan dalam usaha pembikinan teks ucapannya. Namun begitu, teks ucapan ini juga sarat dengan pengemblengan beberapa unsur penanda wacana lain. Kolaborasi beberapa unsur penanda wacana telah menunjukkan bahawa penghubung memainkan peranan penting dalam memastikan ketekstualan ucapan Belanjawan 2019 dan seterusnya dapat mewujudkan makna yang kontekstual, tersusun dan mudah diterima oleh pengguna bahasa.
Nationalism and Identity
Authors: Harney Stefano
Published: December 2023

The nation-state of Trinidad and Tobago offers a unique case for the study of the forces and ideologies of nationalism. This book reveals how this ethnically diverse nation of people of African, East Indian, Syrian, Chinese, Portuguese, French and English descent has provided fertile ground for the creative tension between the imagination of the writer in his or her search for a habitable text of identity and the official discourse on nationalism in Trinidad and Tobago. Stefano Harney examines the changes and influences on the sense of nationalism and peoplehood caused by migration and the ethnicization of migrant communities in the metropoles.
Modernity Disavowed
Authors: Brouwers-Fischer Sibylle
Published: December 2023

On 1 January 1804, the revolutionary slaves of Saint Domingue established the first independent black state in the Americas and proclaimed their break with the French Republic. After more than a decade of protracted bloody battles, the only successful slave revolution in world history ended. The richest sugar colony of the New World was reduced to ashes, and of the troops Napoleon had sent with genocidal intent only very few made it back home. But while the bicentennial of the French Revolution in 1989 and quincentennial of the "discovery" of America in 1992 were lavishly celebrated with acts of State, monuments, conferences, and polemics, the Haitian Revolution's anniversary is bound to be passed over in silence in both the halls of power and metropolitan academies. Although few would doubt the profound effect the slave revolution had on the Western Hemisphere, there has until now been no extended study of it, and some describe Haiti as unrelated to any of the worlds' major civilizations. Modernity Disavowed tells a very different story: the Haitian Revolution is at the core of Western modernity in the Age of Revolution, and one of the reasons for subsequent denial or silencing is that Haiti forced the recognition of this fact on slaveholders and imperial powers. At a time when racial taxonomies were beginning to mutate into scientific racism and racist biology, the Haitian revolutionaries recognized the question of colour and race as a political one and placed claims of racial equality squarely on the agenda. Yet, as the cultural records of neighboring Cuba and the Dominican Republic show, the story of the Haitian Revolution has been framed in terms of barbarism unspeakable violence, outside civilization, outside politics, and beyond human language. From the time of the revolution onwards the story has been relegated to the margins of history; to rumors, oral histories confidential letters and secret trials. Focusing on Cuba, the Dominican Republic and Haiti itself in the context of the African Diaspora, Modernity Disavowed argues that we cannot even begin to understand Creole cultures in the Americas unless we understand how they took shape around various forms of denial of the Haitian Revolution.
Narratives of Resistance
Authors: Meeks Brian
Published: December 2023

This is a hard-hitting analysis of contemporary social, political and intellectual resistance to hegemony in Caribbean societies. Beginning with the “obscure” Henry Rebellion in 1960, at the very end of colonial rule, and ending with a look at the Caribbean Left at the end of the twentieth century, Meeks shows how popular resistance to domination has been manifested in Jamaica and Trinidad. He concludes that, for the small island states and mainland territories of the Caribbean, despite the social and economic crises of the recent past, there is still the possibility of social and political revival and popular renewal.
Mixed Type Basal Cell Carcinoma Treated with Excision and Defect Closure Using Advancement Flap: A Case Report
Authors: Darmaputra I Gusti Nyoman , Ketut Kwartantaya Winaya  , Adelia Suryani  , Herman Saputra  , Putu Setiani
Published: December 2023

Background: Basal cell carcinoma (BCC) is a localized malignant tumor in the basal layer of the epidermis thought to be the result of prolonged sun exposure and associated with gene mutations in most cases. Although rarely metastazises, BCC can cause high levels of morbidity due to its locally destructive nature. There are several modalities for managing BCC, and the defect caused by the lesion can reconstructed by local flap.

Case presentation: We present a 55-year-old woman with a chief complaint of a blackish lump on the left maxillary region, growing bigger, and frequent episodes of bleeding. The lesion was excised and followed by histopathological examination, which revealed mixed subtype BCC. Closure of the defect with an advancement flap was performed with favorable results.

Conclusion: Surgical excision is the best option for managing BCC, while a skin flap is preferred to close defects for lesions on the cheek.
Rethinking Monstrosity and Subversion in Nnedi Okorafor’s Who Fears Death
Authors: Sum Robert K.
Published: December 2023

The concept of monster or monstrosity is not new in African fiction. Monster characters exist in folklore, fantasy, and horror fiction. In many cases they are cast as villainous, unnatural, and horrific. Monsters are portrayed as conduit for supernatural communication. They are constructed to serve cultural roles of reinforcing conformity and policing boundaries. Monsters are also constructed as subversive characters whose existence is not bound by societal norms and conventions but whose boundless freedom opens up doors to possibilities of wish fulfilment. The above significantly influenced the choice of Nnedi Okorafor’s Who Fears Death, as primary text. Who Fears Death offers multi-perspective approach to concept of monstrosity. There is a cultural perspective where superstitious beliefs and prevailing anxiety influence monstrosity. In the text, this perspective is embodied in the culture of Okeke people. It is a potentially fallible perspective as it can transmute even a morally upright person into a monster. Onyesonwu, for instance, is treated as a monster because she is half-caste. Another perspective ascribes monstrosity to an entity depending on their premeditated actions and attitude. This view holds that monstrous characters subject others to untold misery, inhumanity, and harm usually for selfish reasons. This article borrows Gothic concept of monster and postulations from theorists like Jeffrey Cohen to analyse monstrosity in the selected text Who Fears Death. In Gothic fiction, monster character represent vice, unnatural and deviations from regularity attributed to life and nature. The article finds that monstrosity should not be determined by individual’s propensity, uncanniness, or cultural beliefs but rather by actions and attitude which cause harm, hurt or destruction. The findings also affirm that acts of subversive acts are laudable if it they help undermine oppressive cultural practices
Relationship Between Gene Polymorphisms of the Renin-Angiotensin System and Dental Caries Experience
Authors:   Northern State Medical University, Levitsky Sergey N. , Bebyakova Natal’ya A. , Davydova Nadezhda G. , Galieva Aleksandra S.
Published: December 2023

When it comes to studying periodontal diseases and their correlation with general physical pathology, the relationship between the state of oral organs and tissues and the haemodynamic system is of interest; however, research is often conducted without taking into account molecular genetic determinants. The purpose of this article was to determine the relationship of the T704C and C521C polymorphisms of the angiotensinogen (AGT) gene and A1166C polymorphism of the angiotensin II receptor type 1 (AGT2R1) gene with dental caries experience in young people living in the European North of Russa. Materials and methods. The research included 57 healthy male and female subjects (mean age 18.2 years; confidence interval 17.9–19.4) permanently residing in the Arkhangelsk Region. The polymorphisms under study were genotyped by means of pyrosequencing; their allele and genotype frequencies were determined. Angiotensin II level in blood plasma was measured using enzyme-linked immunosorbent assay. Decay-missing-filled (DMF) index and forms of caries in subjects with and without mutant alleles for each gene variant were determined. Results. Young individuals with mutant AGT and AGT2R1 gene alleles showed high DMF index; however, a statistically significant increase in DMF index was observed only in the case of the T704C polymorphism. Angiotensin II levels in young subjects did not differ statistically significantly by sex; however, a tendency was observed towards increased angiotensin II level in the presence of mutant alleles of all the genes under study in the genotype. Among the carriers of the mutant C allele of the T704C polymorphism of the AGT gene, subjects with the decompensated form of caries prevailed, while carriers of the mutant T allele of the C521T polymorphism of the AGT gene showed higher frequency of the subcompensated form of caries. Carriers of the mutant C allele of the A1166C polymorphism of the AGT2R1 gene demonstrated increased frequency of the compensated form of caries with a slight decrease in the frequency of the subcompensated and decompensated forms.
Autosensitization in Malignant Neoplasms
Authors:   N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences, Strekalovskaya Marina Yu.
Published: December 2023

Autoantibody formation, as a physiological mechanism of homeostatic regulation, leads to pathological processes when overexpressed. Autoantibodies are produced when the concentration of autoantigens increases, which occurs as a result of tumour necrotization and metastasizing. Autosensitization in known to develop in chronic inflammatory and tumour processes. It is of interest to clarify the significance of antiinflammatory cytokines for the formation of autoantibodies in malignant neoplasms. The purpose of this article was to identify the link between autoantibody formation and concentrations of anti-inflammatory cytokines in cancer patients. Materials and methods. Immunoassay data of 210 cancer patients of Biokor medical company (Arkhangelsk) were analysed. In the peripheral venous blood, the following were measured: antibodies against phospholipid (IgM, IgG), thyroid peroxidase (anti-TPO) and streptolysin (anti-streptolysin O), anti-double stranded DNA (anti-dsDNA) and anti-ribonucleoprotein (anti-RNP), as well as interleukins (IL) 1β, 4, 6, 10 and 13, and tumour necrosis factor (TNF-α). Results. High frequency of elevated concentrations of anti-dsDNA, antiRNP and anti-streptolysin O in the blood of cancer patients was recorded (51.72, 40.48 and 34.78 %, respectively). Most often, increased levels of anti-dsDNA were found, their mean concentrations being the highest as well. The frequency of elevated concentrations of antiphospholipid antibodies was 11.11 % for IgM and 18.42 % for IgG. Increased anti-TPO levels were observed in 14.29 % of cases. Elevated IL-10, IL-1ß and IL-4 were found in 86.90, 23.81 and 10.81 % of cased, respectively, while IL-6 and IL-13 in 5.71 and 3.85 % of cases, respectively. Mean concentrations of the cytokines under study were within the physiological limits, except for IL-10 and TNF-α, which were increased. Elevated concentrations of autoantibodies were associated with increased blood levels of TNF-α and IL-10. Thus, abnormally high blood concentrations of IL-10, which reduces cellular receptor activity, can indirectly contribute to a decrease in the activity of autoantigen disposal and clearance and prolong autosensitization.
Daily Fat Intake and Lipid Metabolism Parameters in the Blood of University Students in the First and Second Years of Study
Authors:   Gorno-Altaisk State University, Kruglikova Ekaterina V. , Ayzman Roman I. ,   Novosibirsk State Pedagogical University,   Novosibirsk Research Institute of Hygiene
Published: December 2023

New educational environment of the university and changes in social and living conditions are factors that strain the adaptation mechanisms of first-year students. Inadequate diet can decrease the body’s adaptive and compensatory capabilities and affect its basic functions. The purpose of this research was to study the dynamics of the actual fat content in the diet and key markers of lipid metabolism in the blood of university students in their first and second years of study living in a dormitory. Materials and methods. The same sample of healthy students of both sexes (n = 62) aged 18–21 years studying at Gorno-Altaisk State University were examined in 2020 and 2021. Diet information was obtained through a 7–10-day food diary. Blood concentrations of total cholesterol, low- and high-density lipoproteins as well as triglycerides were determined. Results. Daily fat intake of female students (n = 31) in their second year of study (compared with the first year) statistically significantly increased by 9.3 g. At the same time, the girls showed an increase in total cholesterol by 0.2 mmol/l and in triglycerides by 0.2 mmol/l. In the group of male students (n = 31), no statistically significant increase in dietary fats was observed in the second year. However, triglyceride concentrations in the blood plasma of male subjects increased by 0.1 mmol/l. High-density lipoprotein content increased in the second year in both sex groups: by 0.5 mmol/l in female and by 0.2 mmol/l in male respondents. Blood concentrations of low-density lipoproteins remained unchanged during the observed period in both male and female subjects.
Association Between the Degree of Lung Tissue Damage and Functional Capacity in Patients After COVID-19 Pneumonia
Authors:   Kaliningrad State Technical University, Borchev Kirill F. ,   Central City Clinical Hospital
Published: December 2023

Many COVID-19 survivors face various functional disorders. The purpose of this article was to determine the association between the degree of lung tissue damage and functional capacity of patients after COVID-19 pneumonia. Materials and methods. We examined patients (n = 264) aged 46–86 years that had suffered moderate or severe COVID-19 and undergone treatment for bilateral multisegmental pneumonia followed by rehabilitation. Functional capacity was measured using a walk test (at a normal pace to the first signs of exhaustion), taking into account heart rate (HR) and peripheral oxygen saturation (SpO2). The association between the degree of lung tissue damage and test results was analysed using simple and multiple regression analysis. Regression models included the following variables: walking distance, HR and SpO2 at rest and after the test, as well as demographic and clinical characteristics of patients. Results. At normal values of resting SpO2(96.3 ± 1.6 %) and resting HR (81.4 ± 12.1 bpm), fatigue occurred after walking the distance of 130.3 ± 96.4 m, SpO2 decreased to 93.8 ± 3.5 %, HR increased to 96.8 ± 14.0 bpm, the Borg score was 6 ± 3 points. Simple regression analysis showed a negative association of the degree of lung tissue damage with walking distance as well as with resting and after-test SpO2 and a positive association with resting HR. Multiple regression analysis indicated a tendency towards a greater decrease in walking distance and a larger increase in resting HR in men compared to women as well as an increase in walking distance and a reduction in resting HR in patients with chronic diabetes as the degree of lung tissue damage increased. Thus, greater degree of lung tissue damage is associated with decreased functional capacity in patients; however, the extent of this decrease may depend on their burdened history and sex.
Odos sarkoidozė: epidemiologija, etiopatogenezė, klinika, diagnostika ir gydymo principai
Authors: Malinauskaitė Austėja , Žičkevičiūtė Arūnė , Petkevičius Arūnas
Published: December 2023

Odos sarkoidozės etiopatogenezė nėra pakankamai išaiškinta, tačiau, tiriant ligos prie­ žastis, nustatyta, kad sarkoidozės išsivystymui įtakos gali turėti genetiniai ir aplinkos veiksniai, žalingi įpročiai, įvairios infekcijos ir Th1 ląstelių sąlygotas imuninis atsakas. Pagrindinis odos sarkoidozės diagnostikos metodas – bioptato pathistologinis tyrimas. Odos sarkoidozė dažniausiai pradedama gydyti vietiniais gliuokokortikoidais, kalcineurino inhibitoriais, tačiau, esant atsparumui, papildomai skiriami sisteminiai imunomoduliatoriai ir imunosupresiniai vaistais. Tyrimo tikslas. Išanalizuoti mokslinius straipsnius apie odos sarkoidozės epidemiologiją, etiopatogenezę, kliniką, diagnostiką ir gydymo principus. Metodika. „PubMed“ duomenų bazėje pagal reikšminius žodžius atrinkti ir išanalizuoti 2012–2022 m. publikuoti straipsniai, kurie atitiko įtraukimo į literatūros šaltinių analizę kriterijus. Rezultatai. Nustatyta, kad oda yra antras pagal dažnį pažeidžiamas organas, sergant sarkoidoze, ir kartais odos pažeidimas gali būti pirmuoju sisteminės ligos pažeidimu. Odos sarkoidozės diagnozę privaloma patvirtinti histologiškai. Odos sarkoidozei gydyti yra rekomenduojamas vietinis, imunomoduliuojantis sisteminis ir imunosupresinis gydymas, atsižvelgiant į galimą kitų organų patologiją.
Intraokuliniai lęšiai. Literatūros apžvalga
Authors: Gustaitytė Gertrūda , Galgauskas Saulius
Published: December 2023

Tyrimo tikslas. Išanalizuoti naujausią mokslinę literatūrą apie intraokulinių lęšių privalumus, trūkumus ir taikymą klinikinėje praktikoje. Metodika. Temą nagrinėjančios literatūros apžvalga atlikta „PubMed“, „Medscape“, „Medline“, „Science Direct“, „Web of Science“ elektroninėse duomenų bazėse. Rezultatai. Tyrimų duomenimis, intraokuliniai lęšiai didina pacientų regos aštrumą, kontrastinį jautrumą ir mažina korekcijos akiniais poreikį. Įrodyta, kad ištęsto židinio lęšiai pranašesni už vienžidinius lęšius tarpinio ir artimo atstumo matymui (p < 0,05), tačiau abiem lęšiams būdingi nepageidaujami reiškiniai. Naujos kartos monofokalinis „Tencis Eyhance“ lęšis reikšmingai gerina artimo atstumo regos aštrumą, o kartu su ištęsto židinio monofokaliniais lęšiais pasižymi geresne ir statistiškai reikšminga (p < 0,05) tarpinio atstumo regos aštrumo korekcija. Tolimo atstumo matymo korekcijoje reikšmingų pokyčių tarp skirtingų rūšių vienžidinių intraokulinių lęšių nenustatyta. Ištęsto židinio lęšiams būdingas reikšmingai mažesnis artimas regos aštrumas (p < 0,05) ir kontrastinis jautrumas, lyginant su trižidiniais lęšiais. Dvižidiniai lęšiai su papildoma artinimo geba pasižymi mažesniu vaizdinių artefaktų dažniu. Išvados. Sukurta skirtingų vienžidinių, daugiažidinių intraokulinių lęšių, koreguojančių regą, tačiau kol kas nėra nė vieno vienodai gerai artimą, tarpinį ir tolimą atstumus koreguojančio intraokulinio lęšio, nesukeliančio nepageidaujamų reiškinių.
COMBINED UNIT FOR SMOOTH PLOWING
Authors: Кузьмин Виталий Викторович , Тарасенко Борис Федорович
Published: December 2023

Представлены краткий анализ технологий и механизированных средств основной обработки почвы и разработка комбинированного агрегата для гладкой вспашки, в котором совмещены приемы безотвальной обработки почвы с приемами гладкой пахоты. При этом передняя балка выполнена в виде прямоугольной рамы, внутри которой смонтирована набранная из пластин конструкция гнезд для крепления и размещения в шахматном порядке стоек чизельных рабочих органов. Подвижная секция также выполнена в виде прямоугольной рамы, оснащенной шкворнем на центральной поперечной балке, являющимся частью механизма поворота, приваренных на передней и задней балках кронштейнами блоков движения размещаемых в дугообразных смонтированных в передней и в задней части неподвижной секции рамы направляющих. Подвижная секция также оснащена дисками типа ромашка с подшипниками закрепленными внутри вогнутой стороны, стойки которых шарнирно смонтированы в стаканах с секторами-регуляторами зафиксированных в боковых балках и оснащены рычагами связанными с тягами изменения угла атаки дисков, соответственно, для правого и левого ряда, в диапазоне 15…75° по отношению к продольной оси. Причем каждый диск имеет возможность изменения угла наклона по отношению к поверхности поля. Задняя балка неподвижной рамы по бокам с внешней стороны оснащена кронштейнами крепления катка.

The paper presents a brief analysis of technologies and mechanized means of basic tillage and development of a combined machine for smooth plowing, which combines the methods of no-tillage with the methods of smooth plowing. In this case, the front beam is made in the form of a rectangular frame, inside of which is mounted a construction of sockets for fastening and placing in staggered order of racks of cheesel working tools. The movable section is also made in the form of a rectangular frame, equipped with a kingpin on the central cross beam, which is part of the turning mechanism, welded on the front and rear beams brackets motion blocks placed in arc-shaped mounted in the front and rear of the fixed section of the frame guides. The movable section is also equipped with daisy-type disks with bearings fixed inside the concave side, which stands are hingedly mounted in cups with sector-regulators fixed in the side beams and equipped with levers connected with rods to change the angle of attack of disks, respectively, for the right and left row, in the range of 15... 75° in relation to the longitudinal axis. And each disk has the possibility of changing the angle of inclination in relation to the field surface. The rear beam of the fixed frame is equipped with roller mounting brackets on the outer sides.
CORRELATION OF EXPERIMENTAL PARAMETERS DURING THE INTRODUCTION OF DEVICES INTO PRODUCTION
Authors: Лутьянов Александр Владимирович
Published: December 2023

В статье поставлена задача определения взаимного влияния параметров эксперимента в технологической операции чистового растачивания корпусных деталей. Установлены основные внешние факторы эксперимента - давление в системе и величина смазочного зазора в аэростатических втулках. Выявлен тип корреляции этих параметров.

The article sets the task of determining the mutual influence of experimental parameters in the technological operation of finishing boring of body parts. The main external factors of the experiment were established - the pressure in the system and the size of the lubrication gap in the aerostatic bushings. The type of correlation of these parameters is revealed.
AR VR TECHNOLOGY IN MODERN CULTURAL SPHERE
Authors: Сиражиден Дамира Амантайкызы
Published: December 2023

Комплексное исследование применения VR-, AR- технологий в современном культурном пространстве.

A comprehensive study of the application of VR-, AR- technologies in the modern cultural space.
ВНУТРЕННИЙ МАРКЕТИНГ ПЕРСОНАЛА КАК ИНСТРУМЕНТ ПОВЫШЕНИЯ ЭФФЕКТИВНОСТИ УПРАВЛЕНИЯ ПРЕДПРИЯТИЕМ
Authors: Акаева Вероника Роммилевна , Хусаенова Алия Мунировна
Published: December 2023

В настоящее время для повышения конкурентоспособности предприятия значимым является формирование благоприятной среды для развития его сотрудников и накопления интеллектуального потенциала, позволяющие улучшать условия организации рабочей среды и эффективного взаимодействия с заказчиками и конечными потребителями, за счет повышения лояльности и мотивированности на качественное выполнение функциональных обязанностей. В связи с этим в статье уточнена суть внутреннего маркетинга персонала и определены ключевые элементы системы управления, формирующие благоприятную среду для развития предприятия и повышения его конкурентоспособности. Представлена методика, позволяющая оценить удовлетворенность персонала. Определена взаимосвязь организационной культуры с внутренним маркетингом персонала. Представлен практический пример организации внутреннего маркетинга персонала.

Currently, to increase the competitiveness of an enterprise, it is important to create a favorable environment for the development of its employees and the accumulation of intellectual potential, which makes it possible to improve the conditions for organizing the working environment and effective interaction with customers and end users, by increasing loyalty and motivation for high-quality performance of functional duties. In this regard, the article clarifies the essence of internal personnel marketing and identifies the key elements of the management system that create a favorable environment for the development of the enterprise and increasing its competitiveness. A methodology is presented to assess staff satisfaction. The relationship between organizational culture and internal personnel marketing is determined. A practical example of organizing internal personnel marketing is presented.
The Influence of the Contextual Teaching and Learning Approach on Students Social Sciences Learning Outcomes
Authors: Sry Anriyani  , Muh. Yahya  , Syarifuddin Syarifuddin
Published: December 2023

In social studies classes, students' learning outcomes may be impacted by the absence of learning variables used during the teaching process. The aim is to find out how the application of a CTL-based learning approach can influence students' social studies learning outcomes. This research adopts a quasi-experimental research type with a non-equivalent pretest-posttest research design. The sampling technique was carried out purposively on a population of 91 students, resulting in two sample groups including class VIIIa as the experimental group with 30 students and class VIIIb as the control class with 30 students. The instrument used as a data collection tool is an essay test. Data analysis techniques use descriptive statistical analysis techniques and inferential statistics (hypothesis testing). The research results obtained in the form of descriptive statistics show that of the 13 statements regarding the implementation of contextual learning and learning, 7 implementation statements are included in the Effective category, 2 statements in the very effective category, and 4 statements in the Quite Effective category. The results of this observation show that the implementation of contextual learning and learning of social studies subjects is going well. The results of hypothesis testing for social studies learning outcomes through an independent sample t-test show that Sig. count < α or 0.013 < 0.05, which means that there is a significant influence of contextual learning and teaching approaches on the average value of social studies learning outcomes for experimental group students.
Visual Content Strategy Analysis: Enhancing Consumer Engagement in Wardah’s Marketing Approach
Authors: Pranasa Risyaf , Lazuardi Ashar , Putrajip Mohamad
Published: December 2023

This research aims to find out the visual content strategy used by Wardah in building prospective consumers’ purchase requests. This research method uses a qualitative method. This research is descriptive analysis, which is a type of research that provides an overview and describes as clearly as possible the situation without treating the object being studied. Secondary data previously obtained information collected from indirect or second-hand sources, such as government written sources, libraries, official documents, books, research results. The research results obtained include; The packaging used by Wardah is always easy to carry anywhere. Apart from that, Wardah’s distinctive packaging can help differentiate its products from its competitors in the market. Additionally, custom pricing strategies can also be used to respond to market trends or celebrate special events such as holidays, company birthdays, or other celebrations. Wardah always provides education and information regarding facial health and facial skin problems. The visual content on Wardah’s Instagram account has its own meaning and purpose in increasing consumer purchasing power.