bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding the level of animal welfare and associated factors among cat owners in Banyuwangi, Indonesia
Authors: Wulandari Cynthia Retno , Burhanuddin Azhar , Faradina Putri Laura , Wibawati Prima Ayu , Abdramanov Abzal
Published: June 2024

Background and Aim: The “Five Freedoms” concept has shaped the development and implementation of animal welfare assessments. This study aimed to analyze the determinants that impact the understanding of animal welfare among individuals who own cats in Banyuwangi, East Java, Indonesia.

Materials and Methods: Questionnaires and interviews were used in this study to gather data from cat owners. One hundred cat owners in Banyuwangi Regency took part in the study. The classification considered factors such as gender, age, education level, occupation, income, and number of cats. The questionnaire passed both validity and reliability tests and was thus deemed suitable for data measurement. The Chi-square test was employed to investigate relationships within the dataset.

Results: A statistically significant correlation (p < 0.05) was established between cat owners’ level of education, occupation, monthly household income, and their grasp of animal welfare, with the number of cats in their household being a determinant factor. Some cat owners in Banyuwangi undervalue veterinarians’ role in treating and preventing feline health issues. The cat owners’ understanding of animal welfare was unaffected by their age or gender. 59% of the cat owners had a low understanding level, 22% had a moderate understanding level, and 19% had a high understanding level.

Conclusion: In Banyuwangi Regency, 59% of cat owners lack understanding of animal welfare concerns. An owner’s educational background, job, income, and whether they own a cat impact their comprehension of animal welfare principles. Limited awareness of animal welfare and veterinarians’ roles exists in Indonesia. It is crucial to educate government officials, veterinarians, and regional leaders about animal welfare for the sake of sustainability. A complete understanding of this topic demands rigorous research, comprehensive studies, and reproducibility. Equally important is effective publicity for the cat population.

Keywords: animal welfare, cat, education, owner, understanding.
Effect of different synbiotic administration methods on growth, carcass characteristics, ileum histomorphometry, and blood biochemistry of Cobb-500 broilers
Authors: Acharya Arjun , Devkota Bhuminand , Basnet Hom Bahadur , Barsila Shanker Raj
Published: June 2024

Background and Aim: To combat enteric infections and antibiotic resistance in the poultry industry, researchers seek alternatives such as probiotics, prebiotics, and synbiotics as growth promoters. Synbiotics support probiotic growth through the supply of essential nutrients. The study’s objectives were to assess the most effective delivery methods for synbiotics and evaluate their growth, histomorphometric, and hematological impacts on Cobb-500 broilers.

Materials and Methods: Two studies, independently conducted, employed a completely randomized design. One hundred and eighty viable eggs in the first trial were assigned to three groups: Control (T1), sterile water (T2), and synbiotic in sterile water (T3). On the 21st day of hatching, hatchability, day-old body weights, and ileum samples for histomorphometric analysis were recorded. In the second trial, out of 500 viable eggs, 200 eggs were fed in ovo with synbiotics (PoultryStar® sol, Biomin Singapore Pte Ltd, Singapore) on 17.5 days and 300 were set aside without in ovo injection. The treatments were control (T1), in water synbiotic (T2), in ovo synbiotic (T3), combination of in ovo synbiotic and synbiotic in feed (T4), and synbiotic in feed only (T5). On 21 and 42 days, blood, ileum, and visceral organ samples were collected for laboratory analysis. Data on weight gain, daily feed intake, and water consumption were recorded for 42 days.

Results: The initial experiment’s results revealed a decrease in hatchability, slight weight increase, and significant intestinal morphological changes with the use of an in ovo synbiotic. Applying synbiotic through various methods in the second trial yielded better growth results, lower blood cholesterol, and significantly longer (p < 0.05) villi on 21 days.

Conclusion: Using the in ovo method to administer synbiotics lowered hatchability. Use of synbiotics with any method or in combination enhances growth, ileum structure, dressing yield, feed efficiency, and cholesterol levels in blood. Synbiotics enhance gut health and overall performance in broilers when used through diverse approaches.

Keywords: growth performance, gut health, histomorphometry, in ovo, synbiotic.
Developing antibacterial peptides as a promising therapy for combating antibiotic-resistant Pseudomonas aeruginosa infections
Authors: Darwish Rula M. , Salama Ali H.
Published: June 2024

Background and Aim: Antibiotic-resistant Pseudomonas aeruginosa poses a serious health threat. This study aimed to investigate the antibacterial activity of peptide KW-23 against drug-resistant P. aeruginosa and its potential for enhancing the efficacy of conventional antibiotics.

Materials and Methods: KW-23 was synthesized from nine amino acids, specifically three tryptophans and three lysines. The purity of the substance was analyzed using reverse-phase high-performance liquid chromatography. The peptide was identified through mass spectrometry using electrospray ionization. The minimum inhibitory concentration (MIC) values of KW-23 in combination with conventional antibiotics against control and multidrug-resistant P. aeruginosa were determined utilizing broth microdilution. The erythrocyte hemolytic assay was used to measure toxicity. The KW-23 effect was analyzed using the time-kill curve.

Results: The peptide exhibited strong antibacterial activity against control and multidrug-resistant strains of P. aeruginosa, with MICs of 4.5 μg/mL and 20 μg/mL, respectively. At higher concentration of 100 μg/mL, KW-23 exhibited a low hemolytic impact, causing no more than 3% damage to red blood. The cytotoxicity assay demonstrates KW-23’s safety, while the time-kill curve highlights its rapid and sustained antibacterial activity. The combination of KW-23 and gentamicin exhibited synergistic activity against both susceptible and resistant P. aeruginosa, with fractional inhibitory concentration index values of 0.07 and 0.27, respectively.

Conclusion: The KW-23 synthesized in the laboratory significantly combats antibiotic-resistant P. aeruginosa. Due to its strong antibacterial properties and low toxicity to cells, KW-23 is a promising alternative to traditional antibiotics in combating multidrug-resistant bacteria.

Keywords: antimicrobial resistance, peptides, Pseudomonas aeruginosa, synergism.
Embertan-történeti adalék 1997-ből
Authors: Kamarás István
Published: June 2024

1997-ben a Vigilia katolikus folyóiratban jelent meg Felkai Gábor filozófus és szociológus írása az 1995-ös Nemzeti alaptanterv Ember és társadalom fejezetéről, melyről megállapítja, hogy az a monologikus kommunikáció, az individualizmus és az erkölcsi relativizmus jegyében fogant, ugyanakkor nem foglalkozik a tananyag tartalmával. A szerző (a szóban forgó fejezet kidolgozója) ezzel szemben a tanterv szövegének elemzése alapján kimutatja, hogy azt egy olyan interszubjektivista felfogás jellemzi, melyben hangsúlyos a közösség, a család és a nemzeti örökség, amely értékrendjének jellemző vonása a test-lélek-szellem hármasságára épülő emberkép, erkölcsi felfogása pedig egy konszenzust képező etika olyan értékeire épül, mint például az egészség, a jól-lét, az egység, a szabadság, a tudás, a lelkiismeretesség, a felelősség, a feltétel nélküli áldozatos szeretet. Ezután a szerző politológiai elemzéssel kimutatja Felkai antiliberális, apologikusan nemzetvédő, ellenségkereső felfogását.
CIVIC IDENTIFICATION AND VALUE ORIENTATIONS OF THE POPULATION OF BORDER REGIONS OF RUSSIA
Authors: Borisova Olga V. , Sytykh Olga L.
Published: June 2024

The complex social, political and economic processes make more acute the need to study the civic identification and values of the Russian population. Civic identification is a significant component lying in the basis for the formation of civil society. Its function is the creation of unity, common belonging to a single social "organism", the feeling of "we-ness", and the feeling of being part of the whole, the perception of other members of society not as "others" but as "our own" that contributes to the formation of mutual understanding, social solidarity, unity of tasks and interests of individuals and society as a whole. Russian civic identification today considered as a basic identification, along with ethnic, confessional and others. The focus of the article is the analysis of civic identification and value orientations of residents of the border regions of Russia. The results of the research conducted in 2019 in Altai Krai, Novosibirsk Oblast and Altai Republic (n=1418) are presented. According to the results, it has been revealed that some value differences have a pronounced economic determination. Thus, poor financial situation, lack of personal, physical and mental resources led to the formation of different value orientations. The formation of other value orientations, in particular, more oriented on the opportunity to realize their civil rights, to manifest civic activity. Citizens with a low level of economic well-being more often chose health as the main life value. In addition, the comparative analysis of men and women's answers demonstrated adherence to traditional views on life. The most important are family happiness, personal security, and a calm and measured life.
QUALITY OF WORK OF CHILDREN'S RECREATION AND HEALTH ORGANIZATIONS AS ASSESSED BY PARENTS
Authors: Dolgorukova Irina V. , Shavyrina Irina V.
Published: June 2024

The purpose of this work is to identify the quality of work of recreation and recreation organizations for children based on a sociological assessment of parental feedback. The article analyzes the key indicators of the quality of children's recreation and recreation, including the quality of the material and technical base of institutions, the system of ensuring the safety of children, the quality of nutrition and medical care, and others. The regulatory and legal bases for the organization of children's recreation and recreation and the key features of its organization in the regions of the Russian Federation were highlighted. To identify key trends, the results of representative studies conducted by major sociological centers such as VTSIOM, NAFI and others were used. The work is also based on the results obtained by the authors during a sociological study of the organization of recreation and recreation for children, an assessment of the quality and satisfaction with children's recreation, conducted on the basis of the Russian State Social University in the fall of 2023. The participants were selected according to the following criteria: residence in the territory of the Russian Federation, the presence of children /grandchildren aged 7 to 18 years. The most popular formats of children's recreation and recreation, key indicators of the quality of recreational activities for children on vacation were analyzed. According to the results of the study, common methods of working with children in Russian organizations of children's recreation and recreation were identified. The scientific novelty of the research lies in the identification and measurement of key indicators of the quality of child.
SOCIOLOGICAL ASPECTS OF CONTENT AND CORRECTION OF JUNIOR CONVICTED IN THE IDEAL HERITAGE OF N. M. YADRINTSEV
Authors: Golovinov Alexandеr V. , Golovinova Yulia V.
Published: June 2024

The purpose of this work involves a systematic reconstruction of the sociological views of the leader of the movement of Siberian regionalists - N. M. Yadrintsev on the problem of the regime of detention and mechanisms for the correction of juvenile delinquents. The relevance of the study is dictated by scientific, academic and practical tasks. Firstly, this fragment of the enlightenment’s ideological heritage has not yet received adequate coverage in literature. Therefore, the results of our work can contribute to the development of the subject area of the history of sociological thought in Russia. Secondly, the study can be useful in developing the doctrinal foundations of modern state penitentiary policy.
The work is based on the methodology of the “new social history” and the provisions of the “new intellectual history”, which allows us to consider social phenomena through the prism of the individual, and not the state. Textual analysis of N. M. Yadrintsev’s works on the stated topic was also widely used. In the course of the study, it was established that the Siberian thinker advocated the separation of juvenile prisoners from adult inmates and the establishment of a special regime of detention for this category of forced prisoners. The article notes that when considering the problem of keeping juvenile criminals in isolation from society, the Siberian regionalist recorded the consistent humanization of the criminal punishment itself for children. The authors also show that in the matter of re-education of juvenile convicts, the publicist proposed the speedy introduction of educational supervision for the purpose of moral influence on child criminals. In general, it is concluded that N. M. Yadrintsev developed a rational method of correction, which should be based on examples from social life that give concepts about the mutual connection of people.
SPECIFICITY OF MOTIVATION OF POPULATION PARTICIPATION IN IMPROVEMENT OF THE URBAN ENVIRONMENT
Authors: Vorobеva Irina N. , Kytina Polina D. , Trokhimchuk Anna R.
Published: June 2024

The activity of the population in improving the urban environment is an important intangible resource for the formation of urban space. The active participation of the population in decision-making on the transformation of the territory is the key to the effectiveness of coordination of opinions between citizens and city authorities, which minimizes conflicts of interest and becomes the basis for social security and reduces the risk of protest sentiments. An important component for developing mechanisms for involving citizens in improvement practices is a detailed analysis of the motivation for the participation of current activists. The article examines two forms of participation in the improvement of the urban environment and, accordingly, two groups of activists: formal participation in the activities of territorial public self-government bodies and informal participation in the improvement of a house or yard. The theoretical and methodological basis for the study of social participation was the work of E.S. Azarova, M.S. Yanitsky, Kh.K. Anheier, L.M. Salamon, M.V. Nikonova and V.N. Stegniy. Idealistic, personal growth, expansion of social contacts, and compensatory motives are taken as basic. As an empirical basis, we used data from a survey of the population of the city of Cherepovets and the results of in-depth and expert interviews with representatives of the bodies of the TOS “Zarechny” in the city of Cherepovets and activists of this microdistrict. Based on the results of the study, it was proven that the significant incentives of activists taking part informally are focused on interaction, on the sphere of common interests, the motivation is solving problems of society, communication, and changing the surrounding space. The leading motives in the structure of motivation of TOS employees, with also quite pronounced idealistic motives, are significantly focused on the manifestation of personal initiative and are determined by the desire for self-realization.
MULTILEVEL SURGERY IN OBSTRUCTIVE SLEEP APNOEA
Authors: Kumar Arora Dr Gautam , Sebastian Dr Susan K
Published: June 2024

Background/Aims: Obstructive Sleep Apnoea (OSA) is a common public health problem withmultisystem consequences. Surgery for OSA is increasingly being recognized as an effectivetreatment modality, especially in patients where CPAP therapy has failed or is not viable. OSAcan be due to multilevel obstructions; hence the focus is on multilevel surgical correction. Thisstudy illustrates three common levels of upper airway obstruction and their surgical correction.Materials and Methods: Three patients presented with three different levels of airwayobstruction leading to OSA and their surgical management is displayed along with theirclinical outcomes. Surgery includes Barbed Palatopharyngoplasty for collapsing velum andoropharyngeal walls, Endoscopic midline Glossectomy for tongue base obstruction, andEndoscopic Epiglottoplasty for epiglottis collapse.Results: Primary outcomes: the difference between pre and post-operative AHI, RDI index,and ESS. Secondary outcomes: OSA symptoms such as snoring and daytime somnolence andquality of life.Conclusions: This study highlights the clinical effectiveness, safety, and cost-effectiveness ofmultilevel upper airway surgery for OSA.
CLINICALLY PROBABLE SPORADIC CREUTZFELDT JAKOB DISEASE (CJD)
Authors: NALLATHAMBI NAVEENKUMAR
Published: June 2024

Creutzfeldt-Jakob Disease (CJD) stands at the forefront of neurodegenerative disorders, characterized by rapid progression and devastating neurological deterioration. This review encapsulates the current understanding of CJD, encompassing its epidemiology, etiology, pathogenesis, clinical manifestations, and diagnostic modalities. While classified into sporadic, familial, iatrogenic, and variant forms, sporadic CJD remains the most prevalent, with a complex interplay of genetic, environmental, and stochastic factors contributing to its onset. The misfolding of cellular prion proteins (PrPC) into pathological conformers (PrPSc) serves as a hallmark event, instigating a cascade of neurotoxic processes, including protein aggregation, synaptic dysfunction, and neuronal death. Clinically, CJD manifests with a triad of progressive dementia, myoclonus, and characteristic electroencephalographic findings, presenting diagnostic challenges due to its heterogeneous symptomatology and overlap with other neurodegenerative conditions. However, advancements in biomarker identification, neuroimaging techniques, and cerebrospinal fluid analyses hold promise for enhancing early detection and differential diagnosis. Despite extensive research, therapeutic interventions for CJD remain limited, primarily focusing on symptomatic management and palliative care. Nevertheless, emerging strategies targeting prion propagation, immunotherapy, and gene editing offer potential avenues for disease modification and treatment. The profound impact of CJD on affected individuals, families, and healthcare systems underscores the imperative for continued research efforts aimed at unraveling its intricate pathophysiology and developing effective interventions to alleviate its burden.
Na2SO3 Salt Effect on The Ionic Conductivity of Solid Polymer Electrolyte (SPE) Based on Polyvinyl Alcohol
Authors: Pradanawati Sylvia Ayu , Turnip Albert , Laila Hamidah Nur , Buys Yose Fachmi
Published: June 2024

This research is about solid polymer electrolyte (SPE) based on polyvinyl alcohol (PVA) synthesized using a solution casting technique by adding variations of sodium sulfite salt and glycerol as fillers to reduce the samples' bulk resistance for electrochemical energy storage application. The method used is a quantitative analysis based on the test results. X-ray Diffraction (XRD) was used to determine the crystallinity and structure of the solid polymer electrolyte material. Interactions between Na+ ions from salts in SPE were analyzed using Fourier transform infrared (FTIR). The mechanical properties of the SPE samples were analyzed using tensile testing (ultimate tensile strength). Solid polymer electrolyte (SPE) ion conductivity was analyzed using electrochemical impedance spectroscopy (EIS) with temperature variations of 25, 40, 50, 60, and 70°C. The maximum SPE ionic conductivity value is 1.05 × 10-5 S cm-1 in a PVA-Glycerol-Na2SO3 15% sample at 70°C.
The Potency of Adenostemma platyphyllum as Antimelanogenic Agent: In-vitro and In-silico Studies
Authors: Mutmainnah Lutfia , Batubara Irmanida , Ilmiawati Auliya
Published: June 2024

Melanin is a crucial amino acid in determining human skin and hair pigmentation. Excessive melanin production can lead to hyperpigmentation and darkening of the skin. This study aims to assess the capability of Adenostemma platyphyllum as a tyrosinase enzyme inhibitor. It predicts its anti-melanogenic activity through molecular docking with proteins involved in the melanogenesis process. The in-vitro approach was conducted by determining the tyrosinase enzyme inhibition capacity, while the in-silico approach involved ligand binding to target proteins from melanogenesis pathways. The highest tyrosinase inhibition capacity was observed in the ethanol extract, with values of 9.74 Kojic Acid Equivalent (KAE)/g extract (L-tyrosine) and 17.91 (KAE)/g extract (L-DOPA). Molecular docking analysis showed that the binding of eriodictyol 7-O-sophoroside (ΔG = -9.7 kcal/mol) has the best energy affinity for the PKC-β protein, genistein (ΔG = -7.5 kcal/mol) for the tyrosinase-related protein-1 (TYRP1) protein, eriodictyol 7-O-sophoroside (ΔG = -10.2 kcal/mol) for the cGMP protein, vincosamide (ΔG = -7.2 kcal/mol) for the microphthalmia-associated transcription factor (MITF) protein, and dicaffeoylquinic acid (ΔG = -7.4 kcal/mol) for the β-catenin protein. Based on a comparison of in-vitro and in-silico studies, melanogenesis inhibition is more potent in the PKC-β and cGMP pathways than direct tyrosinase inhibition because they exhibit lower binding energy.
Synthesis and Characterization of Silver Nanoparticles Using Bioreductant Andong Leaf Extract (Cordyline fruticosa (L) A. Chev.)
Authors: Sulistiorini Mayang , Gusrizal Gusrizal , Sapar Ajuk
Published: June 2024

Silver nanoparticles are known to play a crucial role in various fields, prompting researchers to undertake synthesis and modification to obtain nanoscale particles. Silver nanoparticles were synthesized using a green synthesis-based chemical method with an extract from Cordyline fruticosa (L.) A. Chev. This study aims to determine the optimum conditions, including pH parameters, reaction time, and concentration, and assess the silver nanoparticles’ stability and characteristics. The research findings revealed that the optimal conditions for synthesizing silver nanoparticles were an extract pH of 11, a reaction time of 60 minutes, a AgNO3 concentration of 1.5 x 10-4 M, and an extract concentration of 0.008%. Characterization showed that silver nanoparticles were spherical, ranging from 5 to 20 nm and had an average hydrodynamic size distribution of 100.8 nm. In conclusion, leaf extract of Cordyline fruticosa (L.) A. Chev. can be utilized as a bioreductant and stabilizing agent, as indicated by stability test results, which showed considerable stability over a storage period of three months.
The Impact of Firm Digital Transformation on Environmental, Social, and Governance Performance: Evidence from China
Authors: Luo Zixu
Published: June 2024

Growing consciousness about sustainability and the onset of the digital era have affected the corporate environmental, social, and governance (ESG) outcomes to the forefront of new debates. This article attempts to use statistical analysis software such as Stata to explore relevant issues. A-share listed firms in Shanghai and Shenzhen between 2006 and 2022 are examined in this research for the sake of exploring how digitalization in businesses affects ESG ratings. Findings suggest a positive correlation between digital initiatives and ESG metrics improvements. These findings are consistent even after multiple robustness checks. Additionally, this article delves into the mechanisms driving this primary relationship, discovering that digital advances in firms enhance ESG scores by easing financial limitations, diminishing information disparities, and bolstering technological innovation. This article further reveals variable impacts based on firm size and geographical location.
CD1d affects the proliferation, migration, and apoptosis of human papillary thyroid carcinoma TPC-1 cells via regulating MAPK/NF-κB signaling pathway
Authors: Liu Qingyuan , Zhai Tong , Ma Lei , Liu Qilun
Published: June 2024

The study aimed to investigate the effect of CD1d down-regulation on the proliferation, migration, and apoptosis of papillary thyroid carcinoma cells and explore the underlying mechanism. CD1d expression was silenced in TPC-1 cells by transfection of CD1d siRNA lentivirus. The proliferation, apoptosis rate, and migration ability of TPC-1 cells were detected by CCK-8 assay, flow cytometry, and scratch assay, respectively. Western blot and qPCR analyses were performed to detect the expression of related proteins. CD1d was highly expressed in TPC-1 cells. Down-regulation of CD1d significantly decreased ALMS1, CDKN3, CDK6, Ki-67, Bcl2 expression, increased Bax and Caspase 3 expression (all P < 0.05), and decreased the migration ability of TPC-1 cells. Gene ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were performed to identify the relevant signaling pathways. KEGG pathway enrichment analysis showed that the differentially expressed genes were mainly enriched in MAPK and NF-κB signaling pathways. Our findings suggest that CD1d down-regulation inhibited the proliferation and migration abilities of TPC-1 cells, increased cell apoptosis possibly via the MAPK/NF-κB signaling pathway.
Advances in synthetic lethality modalities for glioblastoma multiforme
Authors: Richard Seidu A.
Published: June 2024

Glioblastoma multiforme (GBM) is characterized by a high mortality rate, high resistance to cytotoxic chemotherapy, and radiotherapy due to its highly aggressive nature. The pathophysiology of GBM is characterized by multifarious genetic abrasions that deactivate tumor suppressor genes, induce transforming genes, and over-secretion of pro-survival genes, resulting in oncogene sustainability. Synthetic lethality is a destructive process in which the episode of a single genetic consequence is tolerable for cell survival, while co-episodes of multiple genetic consequences lead to cell death. This targeted drug approach, centered on the genetic concept of synthetic lethality, is often selective for DNA repair-deficient GBM cells with restricted toxicity to normal tissues. DNA repair pathways are key modalities in the generation, treatment, and drug resistance of cancers, as DNA damage plays a dual role as a creator of oncogenic mutations and a facilitator of cytotoxic genomic instability. Although several research advances have been made in synthetic lethality modalities for GBM therapy, no review article has summarized these therapeutic modalities. Thus, this review focuses on the innovative advances in synthetic lethality modalities for GBM therapy.
Natural convection and flow patterns of Cu–water nanofluids in hexagonal cavity: A novel thermal case study
Authors: Akram Mohammad , Benhanifia Kada , Brahim Mebarki , Rahmani Lakhdar , Ansari Abu Zaid , Eid Mohamed R. , Hussain Syed M. , Redouane Fares , Jamshed Wasim , Alraddadi Ibrahim
Published: June 2024

The purpose of the current research is to inspect the free convection of the nanofluid (Cu–water) within a hexagonal cavity containing a square obstacle with isothermal vertical walls at

T

h

{T}_{{\rm{h}}}

and

T

c

{T}_{{\rm{c}}}

, and insulated horizontal walls. The aim of this study is to analyze the interaction between the Rayleigh number (

10

3

<
Ra
<

10

5

{10}^{3}\lt {\rm{Ra}}\lt {10}^{5}

), obstacle’s position (top, bottom, and center), and volume fraction of the nanoparticles (

0
<
Ø
<
0.2

0\lt \O \lt 0.2

) on the thermal behavior within the enclosure. Simulations were performed using COMSOL Multiphysics software based on the finite element method. The obtained results were demonstrated using streamlines, isotherms, and average Nusselt numbers. It is concluded that the increase in the Rayleigh quantity

Ra

{\rm{Ra}}

and nanoparticle concentration

Ø

\O

increases the average Nusselt

N

u

av

{\rm{N}}{{\rm{u}}}_{{\rm{av}}}

, which expresses the rate of heat flow in the studied enclosure. Furthermore, the position of the inner obstacle in the middle of the cavity has a more significant thermal efficiency than the other cases.
Psychiatrists' Perspectives on Prescription Decisions for Patients With Personality Disorders
Authors: Sand Peter , Dervisoski Evelina , Kollia Sofia , Strand Jennifer , Di Leone Flavio
Published: June 2024

There is currently insufficient evidence for the use of a specific pharmacological treatment for personality disorders (PD). The research literature lacks a systematic exploration of clinicians’ experiences of pharmacological treatment of PD. The aim of the qualitative study was to examine how psychiatrists make decisions about pharmacological treatment for patients with PD. The interviews were analyzed using inductive thematic analysis. The results showed that ambiguous guidelines had the effect that the psychiatrists often relied on their own experience, or that of their colleagues. As a basis for decisions concerning drug treatment, an interpersonal component was also identified. Some of the psychiatrists in the current study argued that medications may be part of the alliance-building with the patient and that medications were a way of tying the patient to the clinic. Our findings show that it is important to work on how the clinical guidelines should be implemented in practice.
Pengembangan E-Modul Manajemen Perkantoran Berbasis Bot Telegram untuk Membantu Fleksibilitas Belajar Daring Mahasiswa Dimasa Pandemi
Authors: Saeroji Ahmad , Wirawan Arif Wahyu
Published: June 2024

Pandemi COVID-19 telah memaksa dunia pendidikan untuk beradaptasi dengan metode pembelajaran daring. Penelitian ini bertujuan untuk mengembangkan E-Modul Manajemen Perkantoran berbasis Bot Telegram sebagai alat pendukung pembelajaran daring. E-Modul ini dirancang untuk memberikan pengalaman belajar yang interaktif dan mudah diakses oleh mahasiswa dan dosen di tengah keterbatasan yang disebabkan oleh pandemi. Dengan memanfaatkan aplikasi media sosial telegram yang populer dan mudah diakses, E-Modul ini diharapkan dapat membantu fleksibilitas belajar dari dimasa pandemi bagi mahasiswa yang mengambil mata kuliah manajemen perkantoran secara daring atau pembelajaran jarak jauh. Metode penelitian yang digunakan adalah Research and Development (R&D) dengan model ADDIE (Analysis, Design, Development, Implementation, Evaluation). Hasil penelitian ini berupa e-modul manajemen perkantoran berbasis bot telegram yang telah diuji oleh ahli materi, ahli media, dan pengguna (mahasiswa). Dari hasil pengujian menunjukkan bahwa penggunaan E-Modul ini layak untuk digunakan dalam membantu fleksibilitas belajar Mahasiswa dalam pembelajaran daring dimasa pandemi. Selain itu, selain itu juga terdapat saran dan masukkan yaitu berupa penambahan ruang diskusi dan umpan balik untuk mahasiswa.
Hakemlerin terazisi & devletin kılıcı: Devlet yargısının uluslararası ticaretin özneleri üzerindeki etkisinin mikroekonomik yapısı
Authors: Dinç Yasin Uğur
Published: June 2024

Uluslararası ticari uyuşmazlıkların tahkim yoluyla çözümü, tarafların tahkimi yetkilendirmesiyle başlayan ve nihai hakem kararının gereklerine uyulması yahut icrasıyla sonuçlanan bir süreçtir. Uluslararası tahkimin özneleriyle yapılan pek çok anket çalışması, tahkim kararlarının genelde cebri icraya gerek kalmadan, kaybeden tarafın rızasıyla uygulandığına işaret etmektedir. Tahkim sürecinin, kararların gereğinin görülmesini de kapsayacak bir şekilde, kamusal otoritelerin cebir tekeline dayanan olanaklarına ihtiyaç kalmadan kendi kendine işleyişi, devletin sağladığı sosyal kontrolün rolünü yeniden sorgulatmaktadır. Bu çalışmada özel sosyal kontrol sisteminin devletten bağımsızca yürüyormuş izlenimi uyandırmasına sebep olan “tahkim kararlarına gönüllü uyma davranışı”nın oluşumunda devletlerin hukuk sistemlerinin tahkim kararlarının icrasına verdiği desteğin rolü çeşitli somut veriler ışığında değerlendirilmektedir. Yapılan incelemelerde esas soru, farklı devletlerin tahkim anlayışları içerisinde tahkimin ne ölçüde yaşama alanı bulabildiği; bu kapsamda, tahkimin yukarıda bahsedilen başarısının içerisinde devlet yargısının payının niceliğinin ne olduğudur. Aynı zamanda özel sosyal kontrol sistemlerinin devletten bağımsız olarak gerçekleştirdikleri yaptırımların etkililiği de ele alınmıştır. Uluslararası ticaretin öznelerinin stratejik davranışlarında, devletlerin tahkim kararlarına karşı aldıkları tavrın belirleyiciliğinin son derece yüksek olduğu sonucuna ulaşılmıştır.
Bio-beneficial spectrum of Tecoma stans flower extract in vitro for fighting prostate and ovarian cancers with its anti-diabetic and antioxidant activities
Authors: Alfattah Mohammed A.
Published: June 2024

People have long used plants and plant-derived products to treat a wide range of illnesses. In the present work, Tecoma stans flower was extracted using 90% ethanol. Flavonoids and total phenolic constituents of T. stans flower extract were screened, and polyphenolic compounds were assessed using high-performance liquid chromatography (HPLC). Anti-diabetic via α-amylase and α-glucosidase assays, antioxidant via 2,2-diphenyl-1-picryl-hydrazyl-hydrate, ferric reducing antioxidant power, and total antioxidant capacity of T. stans flower extract were assessed. The cytotoxic action for T. stans flower extract was assessed versus WI-38 (human fetal lung fibroblast cells), PC3 (prostate cancer cell line), and SK-OV3 (ovarian cancer cell line). The T. stans extract showed promising in vitro anti-diabetic effect with IC50 = 12.08 ± 0.2 µg/mL and 22.83 ± 0.3 µg/mL for α-amylase and α-glucosidase, respectively. Moreover, T. stans showed good in vitro antioxidant action with IC50= 5.36 ± 0.2 µg/mL for DPPH testing, and the best antitumor impact versus PC3 cells with IC50 = 113.27 ± 1.59 µg/mL. Flow cytometric analysis confirmed the role of T. stans in acceleration in apoptosis of PC3 cells through regulation of oxidative enzymes. These results indicate that the derived materials from T. stans flower have multiple medicinal applications.
Alternativa quirúrgica para recuperar sementales bovinos con fimosis obstructiva severa
Authors: Espin-Iturbe Teresa , Morales-Burguet Jesús , Cervantes-Acosta Patricia , Barrientos-Morales Manuel , Lopez-Aguirre Samuel
Published: June 2024

La fimosis suele desarrollarse secundaria a un caso de acropostitis. Generalmente se inicia como una inflamación aguda de la mucosa prepucial que se acompaña por edema, afectación de la submucosa y daño al tejido conectivo, el cual, para recuperarse sintetiza colágeno y genera tejido fibroso, que provoca estrechez de la luz prepucial e impide la salida del pene. Se presenta una alternativa técnica quirúrgica para tratar casos de fimosis en toros cebú con daño o pérdida de gran cantidad de mucosa prepucial, en los cuales las técnicas de tratamiento tradicionales ya no son exitosas.
Parámetros hematológicos de ovejas Pelibuey adultas bajo condiciones del trópico húmedo de México
Authors: Rodríguez-Diaz Diana Laura , González-Garduño Roberto , García-Herrera Ricardo Alfonso , Chaves Gurgel Antonio Leandro , Muñoz-Osorio Germani Adrián , Chay Canul Alfonso Juventino
Published: June 2024

The aim of this study was to evaluate the haematological parameters of adult Pelibuey sheep under conditions of the humid tropics of Mexico. Erythrocytes (RBC, x106/µL), haemoglobin (HB, g/dL), haematocrit (HTO, %), mean corpuscular volume (MCV, fL), mean corpuscular haemoglobin (MCH, pg), and mean corpuscular haemoglobin concentration were analysed. (MCHC, g/dL), leukocyte count (WBC, x103/µL) and platelets (PLT, x103/µL) through descriptive statistics of 86 adult, non-pregnant, non-lactating sheep. The values were: RCB 10.35±1.08 x106/µL; HB 10.83 ±1.53 g/dL, HTO 33.97 ±3.79%, MCV 32.78 ±2.49 fL, MCH 10.63 ±1.16 pg, MCHC 32.55 ±3.35 g/dL, WBC 10.75 ±5.78 x103/µL, PLT 340±658 x103/µL. The haematological parameters obtained are within the average values of the species.
Complicaciones postquirúrgicas en pacientes caninos con ruptura de ligamento cruzado craneal
Authors: Valenzuela Oliva Solange , Fischer Wiethuchter Christof , Troncoso Toro Ignasio , Morales Orellana Jorge
Published: June 2024

Cranial Cruciate Ligament Rupture (CrCL) is one of the most common orthopaedic pathologies in canines. The objective of this study was to report the complications that occur in canine patients with CrCL treated with an extra-articular stabilization technique. The age, breed and weight of the dogs and their possible relationship with any post-surgical complications were considered. Surgical procedures were based on the description of Flo (1975). Complications were classified as catastrophic, moderate and mild. Clinical data of 80 canines were used, where 7 (8.75%) presented postsurgical complications, 5 presented moderate complications (71.4%) and 2 patients presented mild complications (28.6%), while 73 (91.25%) of patients did not present complications in their recovery. The presentation of CrCL was significantly higher (p<0.001) in adult canines and in patients with a body weight greater than 15 kg (p<0.001).
Desempeño reproductivo y producción de leche de vacas en pastoreo suplementadas vía parenteral con minerales y vitaminas en la fase de transición
Authors: Bustamante Irma , Cáceres Raúl , Perinango Javier , Paredes Manuel
Published: June 2024

El objetivo del estudio fue evaluar los efectos de la suplementación inyectable de minerales y vitaminas sobre el desempeño reproductivo y productivo en vacas en pastoreo. Setenta y dos vacas se asignaron a los siguientes grupos: (1) control (CON, n=18); (2) suplementación inyectable de minerales (SIM, n=18); (3) suplementación inyectable de vitaminas (SIV, n=18); y (4) SIMV (SIM + SIV) (n=18). La suplementación vía IM se hizo a 20 días del preparto, el día del parto y 30 días después del parto. Los tratamientos de SIM, SIV y SIMV resultaron en una disminución del intervalo del parto hasta la primera inseminación artificial y mejora de la producción de leche. La inyección de vitaminas o minerales no difirió con el grupo control en número de partos asistidos, retenciones placentarias, intervalo desde el parto hasta la concepción y tasa de preñez según el número de inseminaciones.
Paraganglioma periaórtico y efusión pericárdica en un perro Golden Retriever: Reporte de caso
Authors: Cortés R. Natalia , Pérez César A. , León Andrés , Chávez Luis E. , Laverde Néstor
Published: June 2024

The case of a 10-year-old Golden Retriever dog treated at the ASMEVET veterinary hospital in the city of Tunja, Colombia is presented. The owner reported that the patient had an intermittent cough for 2 months. The physical examination revealed the patient to be hyperactive, body condition 4/5, and faint heart sounds. Echocardiography, chest x-ray, and electrocardiogram were performed, revealing pericardial effusion, increased size of the cardiac silhouette, and deviation of the S-T segment. Initially, treatment was attempted with antibiotics, diuretics and anti-inflammatory agents, without a favourable response. Two months later, it was necessary to perform emergency pericardiocentesis due to cardiac tamponade, and partial subphrenic pericardiectomy. Histopathological analysis revealed a paraganglioma. The patient survived 673 days after surgical treatment.
Impacto del transporte de la codorniz japonesa a cuatro edades desde la costa a la sierra peruana en el inicio de la puesta y el rendimiento productivo
Authors: Paredes Manuel , Valdivia José , Chilón Deysi , Zambrano Lizbeth , Tafur Lincol
Published: June 2024

The impact of transporting quail of four ages (0, 14, 28 and 42 days) from the coast to the Peruvian mountains on the onset of oviposition and performance in the laying phase was measured. The quails were moved from Lurin (Lima, Peru) at 14 meters above sea level to the Cajamarca valley at 2743 meters above sea level. A batch of 800 recently hatched female chicks in Lurin to distribute them in four groups of 200 birds each. Three groups were installed in Lurin and one group was taken to Cajamarca on the same day of birth. The other groups were transferred at 14, 28 and 42 days of age to Cajamarca. At 42 days of age, the birds were distributed per treatment at a rate of 15 birds per cage (one cage = one repetition). Each treatment had six repetitions. Quails transferred at 14, 28 and 42 days of age reached higher body weights and egg weights at the beginning of laying, with greater egg mass and better laying rate during the productive phase. Quails transferred at 28 and 42 days of age began laying at a younger age and with better feed conversion at laying.
Reporte de infestación por Tunga penetrans (Orden: Siphonaptera) en un canino doméstico de un área rural de Salta, Argentina
Authors: Tolaba Carrillos Gisela Mariana , Noemi Copa Griselda , Hipólito Olmos Leandro
Published: June 2024

Se describe un caso de infestación por Tunga penentrans en un canino de un área rural de la ciudad de Salta (Argentina), con el fin de aportar información a la epidemiologia de esta enfermedad a nivel regional. Se recibió en el laboratorio una muestra de piel de un canino mestizo de tres años de edad que mostraba dolor al caminar. En la parte ventral de la almohadilla plantar del miembro izquierdo delantero presentaba un engrosamiento de forma nodular de coloración clara en su periferia con un centro puntiforme de color más oscuro. En el estudio parasitológico se demostró que se trataba de una infestación por T. penetrans. Este reporte se suma a la información ya disponible en la provincia; sin embargo, es la primera documentación de esta presentación en caninos a nivel regional y en un ámbito rural.
The 13th Nordic-Baltic Conference of German Scholars 2024, Vilnius University, Abstracts
Authors: Bäcker Iris , Daunorienė Justina , Plaušinaitytė Lina , Žeimantienė Vaiva
Published: June 2024

The abstract book contains the abstracts of the papers presented at the 13th Nordic-Baltic Conference of German Scholars (NBGT2024) from 12 to 14 June 2024 at Vilnius University. The subject-specific focus is on questions of German linguistics, literature and cultural studies as well as the didactics of German as a foreign language. Furthermore, the contributions reflect current political discussions on the status of German in the region. The 63 abstracts are presented in alphabetical order according to the authors' surnames.
Predictive factors of disc perforation of the temporomandibular joint (TMJ)
Authors: Jerez Daniel , Laissle German , uenzalida Carlos , Castellon Loreto , Mayorga Jaime
Published: June 2024

Magnetic resonance imaging (MRI) is the gold standard for diagnosing internal derangement, but its accuracy in detecting disc perforations varies. This cohort study included 92 patients who underwent arthroscopic surgery to identify associated variables. The presence of arthroscopically verified disc perforation served as the primary predictor variable, while the radiologist's diagnosis of disc perforation served as the primary outcome variable. Demographic data, patient signs, and symptoms were considered as covariates. Statistical tests were performed with a significance level of 5%. Logistic regression models were used to predict disc perforation, and diagnostic accuracy was assessed using ROC curves. Among 155 joints analyzed (92 patients: 135 females, 20 male), radiologists' MRI interpretations did not significantly correlate with verified disc perforation (p<0.218), showing 14.3% sensitivity and 92.5% specificity. Age, symptomatic onset, joint noise type, osteoarthritis diagnosis, altered disc shape, and Wilkes classification showed significant associations (p<0.05). A logistic regression model used associated variables for disc perforation. Risk factors: symptom onset time, joint crepitus, osteoarthrosis diagnosis by MRI; joint click as protective. The model demonstrated high diagnostic accuracy (AUC of 0.836, 95% CI_0.76–0.91). Radiologists' MRI interpretation was unreliable, but our model accurately predicted disc perforation. Identifying these factors could guide surgical decisions.
How to evaluate the quality of ultrasound images for B-mode and Doppler?
Authors: Dimenstein Renato , Bevilacqua Letícia Comeron , de Souza Daniel Silva
Published: June 2024

The present study evaluated the performance of the Ultrasound (US) and Doppler devices. The methodology was based on the recommendations of the American Association of Medical Physics (AAPM). The study used an image simulator phantom manufactured by Sun Nuclear/Gammex (model 403). The performance evaluation was applied for B-mode and Doppler. The study analyzed 182 devices with 546 transducers from different models and manufacturers. The evaluation parameters were: a) spatial resolution; b) depth of view c) image contrast; d) visualization of anechoic objects; d) velocity; e) sensitivity for (Doppler Mode); and f) artifacts in the images. The evaluation indicated that 43,95% of the probes showed some type of non-compliance, directly affecting the accuracy of the medical diagnosis. The present investigation indicates the need to carry out image quality evaluation to verify the degradation of the probes to minimizing possible errors in diagnostic imaging due to inadequate performance of the US equipments.
Resection of a giant gastrointestinal stromal tumor and subsequent gastric reconstruction
Authors: Weber-Sánchez Alejandro , Weber-Álvarez Pablo
Published: June 2024

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms of the digestive tract (80%). The stomach is the most commonly affected organ. Complete resection of the tumor is the only curative treatment. The size and number of mitoses are parameters to determine the prognosis and the use of adjuvant therapies. Although sometimes the GIST is giant it should be completely resected and if possible the stomach reconstructed to preserve function and quality of life.
Incidence of post ERCP biliary Ascariasis diagnosed on ultrasound
Authors: Khan Shehzad , Khan Jehangir , Babar Shah , Mahmood Rashid , Ahmad Abbas , Hadi Sanya
Published: June 2024

Ascaris lumbricoides are familiar with the roundworm that causes biliary infections in humans. Nevertheless, ascariasis is primarily found in the jejunum and transferred in numerous body parts with the intake of Ascaris lumbricoides present in food and water. These study methods were implemented at the Saidu Teaching Hospital Radiology department from December 2021 to January 2023. This study includes the participants suffering from biliary ascariasis admitted or visited Saidu Teaching hospital in that time frame. Clinical assessment of the participants was done based on the appearance of signs and symptoms present in them. The participant's laboratory test was done to determine the level of basic body parameters, after that ultrasonography was used to diagnose the presence and appearance of worms. Endoscopic retrograde cholangiopancreatography (ERCP) was used to extract worm from biliary channels, and the incidence of post-ERCP biliary ascariasis was accessed with ultrasonography. This study's results show the presence of numerous types of worms in biliary channels of patients. Also, the level of body parameters, for instance, neutrophil, hemoglobin, and others were compared at the time of admission, and at the time of discharge from the hospital. Furthermore, the incidence of post-ERCP biliary ascariasis was reported as 4% in females, and 1% in males respectively.