bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating the role of G-quadruplexes at Saccharomyces cerevisiae telomeres
Authors: Stinus Sonia , Rosas Bringas Fernando R. , Wanders Lisa , Chang Michael
Published: May 2022

The G-quadruplex consensus motif G≥3NxG≥3NxG≥3NxG≥3 is found at telomeres of many species, ranging from yeast to plants to humans, but the biological significance of this fact remains largely unknown. In this study, we examine the in vivo relevance of telomeric G-quadruplexes in the budding yeast Saccharomyces cerevisiae by expressing a mutant telomerase RNA sub- unit (tlc1-tm) that introduces mutant [(TG)0–4TGG]xATTTGG telomeric repeats instead of wild-type (TG)0-6TGGGTGTG(G)0-1 repeats to the distal ends of telo- meres. The tlc1-tm telomere sequences lack the GGG motif present in every wild-type repeat and, therefore, are expected to be impaired in the formation of G-quadruplexes. Circular dichroism analysis of oligonucleotides consisting of tlc1-tm telomeric sequence is consistent with this hypothesis. We have previously shown that tlc1-tm cells grow similarly to wild-type cells, suggest- ing that the ability to form telomeric G-quadruplexes is not essential for te- lomere capping in S. cerevisiae cells.
Breaking the clip for cargo unloading from motor proteins: mechanism and significance
Authors: Obara Keisuke , Kamura Takumi
Published: May 2022

The mitochondrion is an essential organelle involved in ATP generation, lipid metabolism, regulation of calci- um ions, etc. Therefore, it should be inherited properly by newly generated cells. In the budding yeast Saccha- romyces cerevisiae, mitochondria are passed on to daughter cells by the motor protein, Myo2, on the ac- tin cable. The mitochondria and Myo2 are connected via the adaptor protein Mmr1. After reaching daughter cells, mitochondria are released from the actin-myosin machinery and move dynamically. In our recent paper (Obara K et al. (2022), Nat Commun, doi:10.1038/s41467-022-29704-8), we demonstrated that the regulated proteolysis of Mmr1 is required for the unloading of mitochondria from Myo2 in daughter cells. Sequential post-translational modifications of Mmr1, i.e., phosphorylation followed by ubiquitination, are essential for Mmr1 degradation and mitochondrial release from Myo2. Defects in Mmr1 degradation cause stacking and deformation of mitochondria at the bud-tip and bud-neck, where Myo2 accumulates. Compared to wild-type cells, mutant cells with defects in Mmr1 degradation possess an elevated mitochon- drial membrane potential and produce higher levels of reactive oxygen species (ROS), along with hypersensi- tivity to oxidative stress.
Effectiveness of Multimedia and Education using Lecturing Method on Role of Vitamin D for Health Cadres
Authors: Dewi Sumartini , Sulistyo Adityana , Sumardi Erwin , Lestari Eka Puji , Wijaya Kevin Sulay
Published: May 2022

Objective: To investigate the differences in the effectiveness of learning methods between multimedia and lecture methods on benefits of vitamin D for health from the perspective of health cadres' knowledge,. Methods: This study was an experimental study with a pre-and post-test design. The knowledge of health cadres was assessed using a questionnaire. The questionnaire was distributed before and after the health cadres received vitamin D education by two different methods. Data analysis was conducted using paired and independent t-test with a significance level of p <0.05. Results: A total of 59 health cadres participated in this study. Prior to education, the median test score for the multimedia group was 9.45, while the median test score for the lecture group was 82.70. After the education, the multimedia group and the lecture group got a median test score of 10.84. The multimedia method and lecture method significantly increased health cadres' knowledge with p-values of <0.02 and 0.003, respectively. There was no difference in the multimedia method's effectiveness compared to the lecture method in increasing the knowledge of health workers about vitamin D's role in health (p=0.62). Conclusion: The multimedia education method is as effective as the lecture method in increasing health cadres' knowledge about the role of vitamin D in health.
Correlation between Serum Interleukin-6 Level and Modified Rodnan Skin Score in Systemic Sclerosis Patients
Authors: Riswandi Dania Artriana , Dewi Sumartini , Rahmadi Andri Reza
Published: May 2022

Objective: To determine the correlation between serum levels of IL-6 and MRSS in systemic sclerosis patients. Methods: This was a crossectional observational study on patients with SSc visiting the Rheumatology Clinic of Dr. Hasan Sadikin General Hospital Bandung, Indonesia from January 2019 to December 2020. Registered SSc patients, with validated MMRS by a rheumatologist, and available biological materials for IL-6 measurement were included. Patients with other autoimmune diseases, acute infection, diabetes mellitus, and obesity were excluded from this study Results: Of the 51 SSc patients, 42 patients met the inclusion criteria. Women comprised the majority of these patients (95.2%), while patients’ mean age was 43±12 years. The mean duration of disease was 20 months, with diffuse SSc (78.6%) as the most frequent type. Bivariate analysis showed that IL-6 was positively correlated with MRSS (100-scale) with r=0.397 and p=0.005. Conclusion: There is a medium positive correlation between MRSS and interleukin-6 serum among systemic sclerosis patients visiting Dr. Hasan Sadikin General Hospital Bandung, Indonesia.
Hook effect and serum KL-6 in Patients with Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)
Authors: Pranggono Emmy Hermiyanti , Moenardi Valentine Natasya , Syukrie Alvy , Dewi Sumartini
Published: May 2022

Objective To determine whether serum KL-6 can be used as an alternative diagnostic tool for Systemic Sclerosis-associated ILD (SSc-ILD). Method This was a cross-sectional study with compatibility analysis of SSc patients visiting the rheumatology clinic of Dr. Hasan Sadikin General Hospital, Bandung, Indonesia in 2019-2020. Inclusion criteria were aged 18-60 years, diagnosed with SSc, restrictive spirometry results followed by HRCT thorax, having stored biological materials (<2 years) for serum KL-6 examination, and body mass index of <23 kg/m2. Patients with pneumonia, tuberculosis, history of tuberculosis, malignancy, and cardiac decompensation were excluded. Serum KL-6 level of >397.5 unit/mL was declared as ILD. The compatibility analysis was performed using the Cohen’s Kappa test. Results: Thirty-eight subjects, mostly women (94.7%), with mean age of 39 years participated in this study. Most of the subjects suffered from diffuse systemic sclerosis subtypes (57.9%). Subjects had received cyclophosphamide (10.5%), MMF (2.6%), and other medications. Almost all subjects (97.4%) demonstrated ILD features on HRCT thorax. The median serum KL-6 level was 53.22 Units/mL, which was much lower than the findings in other studies, but the hook effect could not be proven. The Kappa coefficient was found to be 0.003 with a p-value of 0.811. Conclusion There is no compatibility between serum KL-6 level and ILD features based on HRCT thorax in SSc-ILD. The presence of hook effect needs more attention.
"Exploration of the Phenomenon of Human Resilience in Literary Texts"
Authors: Pachore Arun Duryodhan , Bhandare Prashant Babar
Published: May 2022

The challenging and threatening circumstances give human life a boost or energy to use human brain for imagination. Human brain is gifted or blessed with power of imagination to dive deep into everything that comes to him in the destructive form. Perhaps it must be an evil omen that
the entire world is passing through the stage of world's most ever witnessed painful suffering that is Covid-19. Natural calamities such as earthquake, flood, drought etc. have tremendously given a jolt to human peace, comfort and life itself on one hand and suffering and horrors caused by
Genocides, War, Holocausts, Epidemics, Plague and measureless experiences of sexual exploitation like rape and torture on the other hand. But human being always hopes for better prospect though he or his ancestors are an eyewitness to all these life- threatening occurrences. One reason of
his overcoming all these sufferings and horrors beyond his worst dreams is that he that is human being has proved his admirable power of human resilience that make him strong enough to adapt to the situation to overcome it with fortitude and hits back to the situation. It is well said that
the pain you feel today is the strength you feel tomorrow. For every challenge encountered, there is an opportunity for growth. The resilience of human being has been accepting challenges in its various forms since time immemorial. It helps him to withstand such horrendous attacks as war,
emotional and physical violation, brutality, deprivation, acute poverty, disasters and even life-threatening illness.
The Concept of "Foreigner-Within": Exploring the Diasporic Dilemma in Maxine: Hong Kingston's The Woman Warrior: Memoirs of a Girlhood Among Ghosts
Authors: Nandi Srima
Published: May 2022

Maxine Hong Kingston's The Woman Warrior: Memoirs of a Girlhood among Ghosts explores the theme of identity friction and the dilemma of hyphenated immigrants among Chinese Americans in the nation of nationsμ (Behdad, p. 113). Kingston demonstrates the discourse of exclusion
with the Chinese Americans who have settled in America due to the phenomenon known as the Gold Rushμ in America. This paper will lay emphasis on Kingston˙s own aunt, Moon Orchid who travels to America after thirty years to meet her husband and claim her position as his wife. The poignant
rejection by her husband, who has totally become an "American" by creating an American identity for himself, rejects his Chinese wife after getting an American wife. The novel speaks of the disappointments of the Chinese American migration from China, the Gold Mountainμ of America. Kingston
has worked hard and struggled to give meaning and voice to the marginalised community to the women like her mother and aunts. This paper will delve into the concept of "foreigner-within" (Lowe, p.5) among the Chinese American and the dilemma of identity in the foreign land. It will also explore
the complex ways in which immigrants understand the notions of 'identity' and 'home in the adopted land. The racial and cultural differences experienced by the Chinese Americans in a "forgetful nation" (Behdad, p. xiii) is a painful experience. Kingston narrates all these difficult times through
a new narrative form that she has discovered and that is the "talk-stories". Through the talk-stories she narrates stories of oppressions that ultimately becomes stories of defiance and through this device the dilemma of identity and the concept of "foreigner-within" will be articulated in
this paper.
Science in Scriptures —Analysing the Presence of Modern Technology in Ancient Indian Mythology
Authors: Dastidar Ankana Ghosh , Chakraborty Ayon , Tripathi Abhishek
Published: May 2022

Myths are the study and interpretation of sacred tales (which can often be religious) of any particular culture or civilisation and Mythology as the dictionary suggests is the study of these Myths. This paper attempts to study and analyse the various instances where the depiction of
Modern scientific technology is being found in the various mythological scripts in India.
Measuring optic nerve sheath diameter using ultrasonography in patients with idiopathic intracranial hypertension
Authors: Dağdelen Kenan , Ekici Merve
Published: May 2022

Abstract Background: Idiopathic intracranial hypertension (IIH) is primarily a disorder of obese young women characterized by symptoms associated with raised intracranial pressure in the absence of a space-occupying lesion. Objective: To compare the mean optic nerve sheath diameter (ONSD) measured using ultrasonography (USG) in patients with idiopathic intracranial hypertension (IIH) and normal healthy individuals. Methods: A prospective study. Ninety-seven participants aged 18-80 years were divided into two groups as patients with IIH (n=47) and the control group (n=50). The ONSD was measured using ultrasound with a 10-MHz probe. ONSD was measured 3 mm behind the optic disc. Receiver operating characteristic (ROC) curve analysis was performed to determine patients with IIH using ONSD. Results: Body mass index was higher in the IIH group compared with the control group (p=0.001). The mean ONSD was statistically significantly thicker in the IIH group (6.4 mm) than in the control group (4.90 mm). The cut-off value of ONSD in patients with IIH was measured as 5.70 mm. There was a significant negative correlation between ONSD and age (r:-0.416 and p<0.001). There was a positive correlation between BMI and ONSD (r: 0.437 and p<0.001). Conclusions: Ultrasound can be a reliable, non-invasive and rapid tool to measure ONSD in monitoring patients with IIH. After the first diagnosis of IIH, based on neuroimaging and measuring intracranial pressure using invasive methods, ONSD can be used in treatment and follow-up.
Distrés psicológico y miedo a la Covid-19 en estudiantes de enfermería antes de la colocación clínica: un estudio transversal
Authors: Belén Subirón-Valera Ana , Carmen Lucha-López Ana , Rodríguez-Roca Beatriz , Urcola-Pardo Fernando , Anguas-Gracia Ana , José Satústegui-Dorda Pedro , Teresa Fernández-Rodrigo María , Antón-Solanas Isabel
Published: May 2022

RESUMEN Objetivo: Determinar el grado de angustia psicológica y miedo al COVID-19 que experimentan los estudiantes de pregrado de enfermería que estaban a punto de empezar sus prácticas clínicas. Método: Se realizó un estudio transversal en 100 estudiantes de enfermería de segundo y tercer año de la Universidad de Zaragoza (España). Las medidas incluyeron la Escala de Miedo a la COVID-19 y la Escala de Depresión, Ansiedad y Estrés. Resultados: Normalmente, los estudiantes de enfermería no se consideraban vulnerables a la COVID-19. Sin embargo, se observó una asociación significativa entre el nivel de distrés psicológico de los estudiantes de enfermería y la convivencia con familiares o personas percibidas como vulnerables a la infección (p = 0,035). Los resultados del Escala de Depresión, Ansiedad y Estrés revelaron un bajo nivel de distrés psicológico en general; la Escala de Miedo a la COVID-19 indicó un miedo moderado (2,94). Conclusión: Los estudiantes de enfermería que vivían con sus familiares experimentaron mayores niveles de estrés debido al riesgo percibido de transmisión, pero tenían menos miedo a la pérdida de trabajo e ingresos. La ansiedad en nuestra muestra se asoció principalmente con el desconocimiento de su próxima ubicación de colocación.
FEELINGS EXPERIENCED BY MOTHERS AND CHILDREN/ADOLESCENTS WITH SICKLE DISEASE IN THE CONTEXT OF THE COVID-19 PANDEMIC
Authors: Brito Luana Santana , Morais Aisiane Cedraz , Suto Cleuma Sueli Santos , Silva Josielson Costa da , Jenerette Coretta Melissa , Carvalho Evanilda Souza de Santana
Published: May 2022

ABSTRACT Objective to know the feelings of children/adolescents with Sickle Cell Disease perceived by mothers and to identify feelings experienced by mothers of children/adolescents with Sickle Cell Disease after the emergence of the COVID-19 pandemic. Method qualitative study, developed in a city in the state of Bahia with the participation of 19 mothers of children and adolescents with Sickle Cell Disease. Data were obtained between March and April 2020 through semi-structured interviews via WhatsApp calls, which were submitted to thematic, factor and similarity analysis after transcription. Results the participants reported feeling overloaded due to dedicating themselves full time to the care of their children, who were more vulnerable and emotionally unstable due to social distancing. Therefore, strategies were adopted by mothers, intending to help adaptation and stress reduction - provided by the context of the pandemic - for themselves and in their children. Conclusion mothers of children/adolescents with Sickle Cell Disease need to be supported and instrumentalized in order to implement care centered on the psychoemotional dimension and seek specialized help, especially regarding feelings triggered due to the need to maintain the therapeutic routine of their children in the midst of the pandemic.
FORMAÇÃO DOCENTE E EDUCAÇÃO ESCOLAR QUILOMBOLA: COMPREENSÃO ATRAVÉS DE UMA ANÁLISE DA LITERATURA
Authors: Costa Pedro Léo Alves , Andrade Luciano Pires de , Andrade Horasa Maria Lima da Silva
Published: May 2022

O presente estudo tem por objetivo examinar a formação docente para atuar na Educação Ecolar Quilombola (EEQ). Para tanto, fez-se uma revisão sistemática da literatura em trabalhos indexados na Scielo, Scopus e Web of Science, nos últimos dez anos. Utilizou-se os descritores “educação” e “quilombola” e “quilombola” and “education”, totalizando 216 na busca geral. Após a seleção dos critérios de exclusão e inclusão, bem como a triagem final, restaram 14 artigos como amostragem. Analisando os trabalhos selecionados, pode-se concluir que a formação do docente na EEQ: i) não foi uma temática de pesquisa comum ou primária nos estudos, mas sim um tema transversal a algum trabalho que abordou outras questões; ii) há desafios, ausências, barreiras e incertezas no que toca à sua concepção e efetivação. Sendo necessário, portanto, diante da importância da EEQ e da mudança paradigmática da ciência da educação no cenário hodierno, um melhor aprofundamento da temática pelos estudiosos e a adequação da formação docente quilombola às Diretrizes Curriculares vigentes.
Cuidados de enfermería al paciente que ha sufrido una quemadura
Authors: Olaya López Catalina Amparo , Palomino Heidys , Padilla Constante Kisi Nayidis
Published: May 2022

La atención al paciente quemado es uno de los retos en los que se ve abocado el profesional de enfermería. De su habilidad, fundamentación científica y buen desempeño depende la rápida recuperación del paciente, puesto que, el profesional de enfermería es miembro activo del equipo multidisciplinario y debe tener un aporte en esta situación. De lo anterior eso nace el interés de las autoras en el abordaje del tema de la forma más sencilla en la que se pueda realizar este cuidado, considerando los aspectos básicos de clasificación de las quemaduras, el cálculo de la extensión y la reposición de líquidos; además de consideraciones en la parte holística del paciente. Se pretende que, una vez comprendida la presente literatura gris, sea capaz de analizar cualquier literatura con respecto al tema.
P3 20/05 v1
Authors: Gul Maria
Published: May 2022

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Birth outcomes for infants born to mothers with COVID-19 at a tertiary care hospital in Telangana
Authors: Ananthula Hima Bindu , Vellanki Janaki
Published: May 2022

The coronavirus disease 2019 (COVID-19) pandemic has primarily affected adults of higher age groups, and the effect of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears to be less severe in infants and neonates. This study aims to evaluate the clinical manifestations, management, and short-term outcomes of SARS-CoV-2 neonates born to mothers with COVID-19 in a tertiary care hospital in Telangana, India.

The study is an observational study of neonates born to COVID-19-positive mothers delivered at Gandhi Hospital, Hyderabad, Telangana from 1st July 2020 to 31 May 2021.

Infection with SARS-CoV-2 was detected in 2.06 percent of neonates born to covid positive mothers. About 12.5% of those were symptomatic, with respiratory distress syndrome as the most common clinical manifestation. Symptomatic treatment was usually effective, and most neonates were discharged.

The COVID-19 virus rarely affects the fetus during pregnancy and has low neonatal mortality, but is associated with adverse neonatal morbidity. Vertical transmission has not been observed in the majority of reported cases. A COVID-19 vaccine provides the best protection against the known risks of pregnancy for women and babies, including admission to the intensive care unit and preterm birth.
Knowledge, attitude and perception of perimenopausal and menopausal changes in middle age women (40-45 years) of urban population
Authors: Nagarwala Razia M , Banole Sayali P , Dabadghav Rachana P , Shyam Ashok K , Sancheti Parag K
Published: May 2022

: Menopause is the period in women’s life when menstruation ceases for atleast 12 months. Perimenopause refers to the time during which body makes the natural transition to menopause. M Majority women attain menopause without having adequate knowledge and approaches to cope with the menopausal changes. So, they face many physical and psychological disorders during their menopause. So knowledge and awareness regarding it is very necessary.

: To study knowledge, attitude and perception of perimenopausal and menopausal changes in middle age women of 40-45years of urban population.

: It was a cross-sectional study in urban population (community set-up).

: 100 female participants between the age group 40-45 years having regular or irregular menstrual cycle were asked to fill a self-made questionnaire which was face validated.

: Descriptive analysis.

: 99% women have heard about the term perimenopause and menopause of which 96% women have knowledge about it. 46% were aware about the physical symptoms, 84% about the emotional/psychological symptoms, 78% about the hormonal deficiency related symptoms and 92% about the bone and muscle related problems. 41% of women had knowledge about Hormonal Replacement Therapy. 51% of the women have knowledge about the exercise which helps cope with perimenopause and menopause symptoms.

: More efforts are needed for creating awareness about symptoms, complication and risk factors associated with perimenopause and menopause and importance of exercise as the first line of treatment option to cure the symptoms.
Effect of vitamin D supplementation on serum VEGF levels in vitamin d deficient polycystic ovarian syndrome patients
Authors: Suman Surbhi , Singh Alpana , Nayan Deepika , Banerjee B D , Grover Chander
Published: May 2022

To estimate and compare serum VEGF levels before and after vitamin D supplementation in vitamin D deficient PCOS patients.

The present study was conducted in Department of Obstetrics and Gynaecology in collaboration with Department of Biochemistry at University College of Medical Sciences (UCMS) and Guru Teg Bahadur Hospital (GTBH), Delhi from November 2017 to April 2019 (including enrollment of subjects, data analysis and thesis writing). Considering a standard deviation of 36.5 before supplementation and 42.7 after supplementation in VEGF levels in case of PCOS patients in study of Irani et al., to estimate an absolute difference of 31 units pg/ml decrease in VEGF levels, at α= 5% and power= 80%, a sample of 26 cases is required. Since there is a follow up of 3 months adding an attrition of 15%, the total sample size becomes 30 cases.

Significant increase in serum vitamin D levels post supplementation was observed from pre supplementation 9.524±4.41 to post supplementation 32.07±12.40; p-value <0.001. We observed significant fall in angiogenesis marker, serum VEGF levels post vitamin D supplementation from 773.547±344.173 to 639.97±119.02, p value 0.004 which suggests negative correlation between serum Vitamin D and serum VEGF levels.

Vitamin D supplementation in PCOS patients who are vitamin D deficient, leads to significant fall in angiogenesis marker serum VEGF, which is manifested as improvement in clinical and biochemical parameters in these patients.
Colposcopic findings in human immunodeficiency virus positive patients in Port Harcourt
Authors: Sapira-Ordu Leesi , Nyengidiki T K  , Bassey G  , Sapira M K  , Wegbom A I  , Awoyesuku P A  , John D H
Published: May 2022

Colposcopy is an outpatient procedure that involves visualization of the cervix, vagina and vulva using a magnifying optical instrument called the colposcope. Human Immunodeficiency Virus infection is associated with increased incidence of cervical malignancies which can be detected by colposcopy.

To determine prevalence of premalignant and malignant lesions of the cervix using colposcopic assessment among HIV positive women at the University of Port Harcourt Teaching Hospital (UPTH), Alakahia between June 2015 and August 2015.

One hundred HIV positive women were recruited by simple random sampling (by balloting) with an uptake rate of 97%. Informed consent was obtained from each individual and data was collected using a semi-structured interviewer administered questionnaire. They all had colposcopic examination. Data analysis was done using SPSS. Ethical approval was obtained from the hospital’s ethical committee before the research was commenced.

Ninety seven out of one hundred subjects had satisfactory colposcopy. The prevalence of premalignant lesions from colposcopy was 53.6%. The mean age respondents; 37.44 ±7.20 years, mean age for premalignant lesions; 37.73 ±7.49 years.The age range was 21-56 years.

Thirty-four (35.4%) had coitarche before eighteen years of age, fifty-five (57.3%) had it after the age of eighteen, seven (7.3%) had no idea. Majority (68.8%) have had two or more sexual partners in their lifetime. The mean CD count was 543.77cells/mm.

There was high prevalence of premalignant lesions among the HIV positive women. This indicates that a routinely scheduled colposcopic examination of the cervix, together with directed may aid early detection and treatment of the lesions, which will further decrease the incidence of cervical cancer among this population.
Effect of maternal oral hydration in oligohydramnios
Authors: Vijan Tanya , Singh Salomi , Patil Shaifali K
Published: May 2022

Thestudy is to compare the effect of oral hydration in pregnant women with moderate isolated oligohydramnios (AFI 5-8 cm) over 28 weeks of gestation.

The study was conducted on 50 pregnant women, randomized into two groups, each group having 25 women. Study group comprising 25 pregnant women with moderate oligohydramnios from study group were given 2 litres of water in 2 hours for 7 days apart from their routine water intake and ultrasound was done after 2 hours after completion of water intake, 24 hours and then after 7 days. While 25 pregnant women with moderate oligohydramnios from control group were give routine medications as per the Institute protocol and was explained to have routine water intake. Ultrasound was done after 2 hours after registering the case as control, 24 hours and 7 days.

: Amniotic fluid index improved in 19 cases as compared to pretreatment levels in study group. Amniotic fluid index worsened in 21 pregnant women from control group. The difference was statistically significant (p<0.05). In this study, there is significant rise in AFI after oral hydration of pregnant women (p<0.05)

Oral maternal hydration therapy with water improves the level of amniotic fluid index significantly in third trimester of pregnancy. Hydration with water is not associated with any adverse maternal outcomes.
Occurrence of urinary tract infection and asymptomatic bacteriuria during pregnancy and its association with maternal outcome
Authors: Pavani M  , Lavanya B  , Vindha Aluru Mithra , Reddy M Niharika , Anandkumar H
Published: May 2022

: The pregnancy increases the possibility of the case progressing from asymptomatic bacteriuria (ABU) to urinary tract infection (UTI) with symptoms, which may further lead to pyelonephritis and obstetric outcomes. The adverse outcome may result in premature delivery, low weight at birth, and increased foetal mortality. The present study was proposed to assess the occurrence of Symptomatic UTI and asymptomatic bacteriuria, the microorganisms causing UTI in pregnancy, to assess the socio-demographic characteristics involving the risk factors of UTI and the maternal outcome.

A total of 152 pregnant women with and without symptoms of urinary tract infection were included as a study subject from January 2011 to April 2011. Midstream urine samples were collected and processed following standard bacteriological tests.

In the present study 85 (55.9%) cases were symptomatic UTI and 67 (44.1%) cases were having asymptomatic bacteriuria. was the predominant organism isolated in 61 (49.6%) cases followed by in 24 (19.5%) cases, in 16 (13.0%) cases, CONS 12 (9.7%) cases and in 10 (8.1%) cases. The lower socio-economic status has contributed in 65 (42.8%) cases and the education status of the most of the cases was either high school (47.4%) or primary school (38.8%). Out of 118 cases of vaginal delivery, 101 (85.6%) cases had full term normal delivery, but among 17(14.4%) preterm delivery, 12 (10.2%) were having symptomatic UTI and 05 (4.2%) cases were having asymptomatic bacteriuria..

Our study findings showed that low socioeconomic status and education background were predominant factors associated with increased symptomatic UTI and ABU. There was no significant difference in the prevalence of UTI and ABU with respect to gestational age. It was concluded in the study that the prompt treatment of ABU early in pregnancy significantly reduces the chances of adverse pregnancy outcome. Thus, screening for ABU should ideally be done in the pre-conceptional period. It was also found in our study that higher incidence of UTI was found in third trimester. Hence all pregnant women should be checked for the presence of ABU in the 1st trimester, treated aggressively with suitable antibiotics and promptly followed up.
Ascites in preeclampsia: A case report
Authors: Vazifdar Sharmeen , Gavali Urmila
Published: May 2022

Preeclampsia complicates approximately 2-8% of all pregnancies and is an important cause of maternal morbidity and mortality. Ascites in preeclampsia is a rare complication. We here are presenting a case of a 28-year primigravida with 34 weeks of gestation, a known case of preeclampsia, that was referred to our institute from a primary health centre in view of impending eclampsia. Massive ascites is an unusual complication of preeclampsia which may lead to maternal respiratory compromise, which calls for active termination of the pregnancy within 24–48 hours as it cannot be cured by medical treatment. Its rarity may be due to under-reporting. The incorporation into clinical practice of evaluating the amount of ascites in patients with preeclampsia might prompt the obstetrician to more intensive and more frequent maternal and fetal surveillance to avoid maternal and fetal complications.
Infrastructure Bonds. The Case of Brazil
Authors: Borensztein Eduardo , Cavallo Eduardo A. , Pereira Dos Santos Pablo
Published: May 2022

Debntures Incentivadas or incentivized bonds are securities first issued in 2012 whose interest and capital gains enjoy income tax exemption conditional on using funds to finance infrastructure expenditures. They have a minimum duration at issuance of four years, are denominated in reais and traded in local markets under national jurisdiction. In US dollar terms, the value of bonds issued reached a peak of $9.5 billion in 2019, and the overall number of bonds since inception of the program exceeds 400. The amount of infrastructure bonds issued every year rivals BNDES loans in terms of the total amounts of financing of infrastructure projects. The Brazilian experience with creating a market for incentivized bonds can be useful to other countries in the region seeking to develop long-term financing markets in local currency to finance infrastructure.
Ratio Study of High-Pressure Lubrication and Cutting Parameters Effects on Machining Operations and Its Effect Towards Sustainable Machining: A Review
Authors: Okokpujie Imhade P. , Sinebe Jude E. , Tartibu Lagouge K. , Adeoye Adeyinka O.M. , Kelechi Sylvia E. , Akinlabi Esther T.
Published: May 2022

Machining is the art of developing sustainable mechanical components by transforming solid raw materials into the finished product. Because for any Nation to achieve sustainable development, the Nation must have quality manufacturing industries. This paper summarizes existing articles on the effects of high-pressure lubrication conditions on chip formation and temperature distribution. Also, surface roughness, tool wear, and vibrations in machining operations when considering the current trend. Furthermore, the study of nano-lubricant and their application in reducing friction and temperature were also reviewed. The study also examined other lubrication conditions, cutting parameters with the high-pressure machining operations to draw a definite conclusion. The review confirms that applying a high-pressure lubrication system is very efficient. However, it has some challenges. Cooling technology is not built into the system, discovered during this review. Therefore, the study will recommend a developed machine that can function in multiple faces. Industrial 4.0 additive manufacturing techniques can build the cryogenic system—making the lubricant delivery machine a sustainable technology in machining operation. A high-pressure-cryogenic-MQL lubrication process is needed for sustainable machining operations of various alloys and metal composite materials for automobile, aerospace, and structural applications. The sustainable lubrication system will also help eradicate high-temperature occurrence in the machining region with a sustainable way of removing the chips without experiencing chip breakage at the cutting region.
Efficient Neuro-Fuzzy Identification Model for Electrocardiogram Signal
Authors: Abdelaziz Aouiche , El Moundher Aouiche , Dhaouadi Guiza
Published: May 2022

This paper addresses the performance of the Artificial Neural Networks (ANNs), Fuzzy inference systems (FISs) and Adaptive Neuro-Fuzzy Inference System (ANFIS) for the identification of some nonlinear systems with certain degree of uncertainty. The efficiency of the suggested methods in modeling and identification the responses were analyzed and compared. The Back-propagation algorithm and Takagi-Sugeno (TS) approach are used to train the ANNs, FISs and ANFIS, respectively. In this study we will show how ANFIS can be put in order to form nets that able to train from external data and information compared to ANNs and FISs. In order, it is proposed forms of inputs that can be used along with ANNs, FISs and ANFIS to modeling nonlinear systems. Two nonlinear systems with an electrocardiogram (ECG) signal in the form of simulation and complexity were used to test the identification of the structure presented. Because ANFIS has an inherent capacity to approximate unknown functions and to adjust the changes in inputs and parameters, it can be used to identify the proposed systems with a very high level of complexity. The results show that the ANFIS technique can provide the most ideal approximation when the right structures are employed.
Comparative Functional Analysis of Three MPPT Techniques Applied on a Stand-Alone Photovoltaic System with a Charging Battery
Authors: Messaoud Mayouf
Published: May 2022

This paper presents a comparative functional analysis of a typical stand-alone photovoltaic system (SPV) with a charging battery. Considering the nonlinear behavior of the PV system, a specific methodology based on Tayler’s expansion series is opted for the modelling, control, and optimization. During the proposed steps, a practical PID controller is designed using a dynamic state space averaging approach. This controller is used to track the maximum power point (MPP) and control the battery charging process. To check the validity of this controller, it is applied with three disparate MPPT algorithms to enhance system performances by preventing drift phenomenon against fast changing in cell temperature and solar irradiance, and control the battery pack to conform with the load rating voltage. A typical 2525 W SPV is simulated in short term to capture fast dynamics transitional details. By comparison with practical manufacturer's specifications of the PV panel, the load, and the battery pack; simulation results show particularly, good performances with fuzzy logic controller in terms of speed tracking, MPPT tracking accuracy, voltage quality, and reducing transient fluctuations. The findings of this research substantiate its efficacy, which may serve as a prototype study for the design and realization of stand-alone photovoltaic systems with energy storage.
MATHEMATICAL SIMULATION OF THE MASS DISCRIMINATION IN ELECTRON IONIZATION MASS SPECTROMETRY AND THE POSSIBILITY OF ITS CORRECTION
Authors:   Ioffe Physical Technical Institute of the RAS,  Saint Petersburg, Russia, Pavlova E. S. , Gromov I. A. ,   Institute for Analytical Instrumentation of RAS,  Saint Petersburg, Russia, Antonov A. S. ,   Ioffe Physical Technical Institute of the RAS,  Saint Petersburg, Russia, Gall L. N. ,   Institute for Analytical Instrumentation of RAS,  Saint Petersburg, Russia, Gall N. R. ,   Ioffe Physical Technical Institute of the RAS,  Saint Petersburg, Russia
Published: May 2022

Ion mass discrimination in mass spectrometry with electron ionization is a nonremovable effect, reducing the accuracy of isotopic composition measurement, the exact knowledge of which is extremely necessary in many applications. The reason for these discriminations is the necessity to use additional magnetic field in the ion source, focusing a beam of ionizing electrons. The paper concerns the displacement of an electron beam, the ionization region, and the ion position for various masses in the ion beam during its formation in an ion source optical system, studied by mathematical simulation. Introducing voltage correction on the extraction electrode can significantly, by two orders of magnitude, reduce the discrimination.
INVESTIGATION OF THE SENSITIVITY AND SELECTIVITY OF A THERMOCATALYTIC SENSOR OF HYDROGEN
Authors:   Moscow Aviation Institute, Russia, Ivanov I. I. , Baranov A. M. ,   Moscow Aviation Institute, Russia, Lyamin A. N. ,   Moscow Aviation Institute, Russia, Mironov S. M. ,   Scientific and Technical Center for Measuring Gas Sensing Sensors named after E.F. Karpov, Lyubertsy, Russia
Published: May 2022

The study demonstrates for the first time the high selectivity of catalytic hydrogen sensors to other hydrocarbons (methane, propane, hexane, butane, ethane and ethylene) at an operating temperature less than 70 ºС. Two circuits were used to measure the response of sensors: a Wheatstone bridge circuit and a divider circuit. The hydrogen measurement was conducted at the temperatures ranging from 66 to130 ºС. It is shown that the sensors have a high sensitivity of 25–35 mV/% and a low power consumption of approximately 8.6 mW. The Wheatstone bridge circuit was observed to have the maximum value of selectivity and sensitivity.
QUALITY CONTROL OF WATER PURIFICATION FOR TECHNOLOGICAL AND SCIENTIFIC PURPOSES
Authors:   Institute for Analytical Instrumentation of RAS,  Saint Petersburg, Russia, Gall I. R. , Esikova N. A. , Gall L. N.
Published: May 2022

The high-resolution low-frequency induction dielcometria method was used to compare the degrees of purity of the tap water (St. Petersburg, Russia) obtained by various methods currently in use: steam distillation, bidistillation, as well as membrane distillation separately and combined with deionization. It has been determined that all the above methods of water purification do purify water with sufficient quality, but only bidistillation and deionization produce water that does not contain ionic impurities in the order of 10–7 M.
INVESTIGATION OF OPTICAL FLAT SURFACES OF BEAM-SPLITTING PLATES BY MEANS OF COHERENT OPTICS
Authors:   Saint Petersburg state university of aerospace instrumentation (GUAP), Saint Petersburg, Russia, Maiorov E. E. , Kotskovich V. B. ,   Saint Petersburg state university of aerospace instrumentation (GUAP), Saint Petersburg, Russia, Pushkina V. P. ,   Saint Petersburg state university of aerospace instrumentation (GUAP), Saint Petersburg, Russia, Arefiev A. V. ,   University at the EurAsEC inter-parliamentary Assembly, Saint Petersburg, Russia, Guliyev R. B. ,   University at the EurAsEC inter-parliamentary Assembly, Saint Petersburg, Russia, Dagaev A. V. ,   Ivangorodskii Humanitarian-Technical Institute (branch of) State educational institution for higher  professional education "Saint Petersburg University of Aerospace Instrumentation", Ivangorod, Russia
Published: May 2022

The article presents an experimental setup for measuring the geometric parameters of optical surfaces of details. The relevance of the work is shown since obtaining high-precision and reliable information about the geometric parameters of surfaces has always been an important task of metrology. The paper highlights the optical layout of the interferometer, as well as the technical and operational characteristics of the experimental setup. The objects and method of research are determined. Interferograms were obtained from the surfaces of beam splitters from various manufacturers. The images of interference fields were analyzed, and the main parameters of wave fronts were revealed. The optical surfaces were controlled by an experimental setup with an accuracy of not worse than 0.05 λ. The reflective coatings of beam splitters were studied, and the dependences of the reflection coefficient on the x and y coordinates were obtained. Comparative analysis revealed the preferable option for modern automated interferometers.
Using my career story to foster reflective capacity, hope, and narrative change
Authors: Santilli Sara , Hartung Paul J.
Published: May 2022

My Career Story (MCS) comprises a self-guided autobiographical workbook designed to assist individuals across life’s diverse spectrum to narrate and shape their career stories. We describe the development and use of the MCS and its relevance for all people, including individuals who may be at risk for. Results of a study using the MCS with 20 emerging adults in Northern Italy supported the validity of its use. Specifically, results indicated that individuals shift to more positive, clear, action-oriented language in the stories they tell at the end of the MCS workbook, after constructing their life portraits, as compared with the stories they tell at the opening of the workbook. Also, scores on measures of reflective capacity and hope increased following the MCS intervention. Results of the study further support use of the MCS in career intervention contexts.
 
Keywords: Career construction counseling, My Career Story workbook, Narrative career counseling, Career construction interview, Career intervention
Kadar Nitrogen Urea Darah dan Kreatinin Ayam Pedaging yang Diberikan Tambahan Tepung Belatung Lalat Hitam dalam Pakan Komersial
Authors: Utomo Kurniawan Cahyo , Sulabda I Nyoman , Suharsono Hamong
Published: May 2022

Penelitian ini bertujuan untuk mengetahui kadar Blood Urea Nitrogen (BUN) dan kreatinin dalam darah broiler setelah diberi pakan tambahan tepung belatung Black Soldier Fly (Hemetia illucens). Objek penelitian adalah broiler (Gallus domesticus) galur CP 707 sebanyak 24 ekor yang dipelihara mulai dari Day Old Chick (DOC) dan mulai diberi perlakuan pada umur 14-35 hari. Broiler dikelompokkan menjadi empat perlakuan yaitu: perlakuan kontrol tanpa pemberian tepung belatung (P0); perlakuan dengan penambahan tepung belatung 1% dalam pakan (P1); perlakuan dengan penambahan tepung belatung 2% dalam pakan (P2); dan perlakuan dengan penambahan tepung belatung 3% dalam pakan (P3). Variabel yang diamati adalah kadar BUN dan kreatinin darah broiler dengan pengambilan sampel darah melalui vena Pectoralis externa, kemudian dimasukkan ke dalam tabung vacutainer Serum Separator Tube (SST) non-EDTA dan sampel darah diperiksa menggunakan alat photometer 5010 di Unit Pelaksana Teknis Daerah (UPTD), Balai Laboratorium Kesehatan Provinsi Bali. Hasil menunjukkan rata-rata kadar BUN ayam pedaging P0, P1, P2, P3 berturut-turut adalah 3,10 mg/dL, 2,83 mg/dL, 3,62 mg/dL, 3,98 mg/dL. Rata-rata kadar kreatinin ayam pedaging P0, P1, P2, P3 berturut-turut adalah 0,68 mg/dL, 0,68 mg/dL, 0,70 mg/dL, 0,70 mg/dL. Data BUN dan kreatinin dianalisis dengan uji sidik ragam dan menunjukkan hasil bahwa perlakuan yang diberikan tidak berpengaruh nyata terhadap kadar BUN dan kreatinin darah broiler sehingga pemberian tepung belatung dalam pakan komersil masih relatif aman.
Kadar Globulin Serum Sapi Bali (Bos sondaicus) Pascatransportasi ke Rumah Potong Hewan, Pesanggaran, Denpasar, Bali
Authors: Permana Rizky , Utama Iwan Harjono , Sulabda Nyoman
Published: May 2022

Penelitian ini bertujuan untuk mengetahui dampak transportasi terhadap perubahan kadar globulin serum darah sapi bali pascatransportasi dari Pasar Hewan Beringkit menuju Rumah Potong Hewan Pesanggaran, Denpasar dengan jarak tempuh 21 km. Transportasi dapat mengakibatkan terjadinya stres dan dehidrasi. Untuk mendiagnosis terjadinya stres dapat dilakukan dengan uji biokimia. Uji biokimia yang dilakukan dalam penelitian ini adalah dengan mengukur kadar globulin serum dalam darah. Objek yang digunakan adalah sapi bali jantan yang belum diistirahatkan setelah transportasi sebanyak 20 ekor di Rumah Pemotongan Hewan Pesanggaran Denpasar. Darah di ambil melalui vena auricularis dan dimasukan ke tabung vacutainer yang berisi gel separator. Sampel darah dibawa ke Balai Laboratorium Kesehatan Provinsi Bali untuk segera dilakukan pemeriksaan kadar globulin serum menggunakan mesin Photometer 5010V5+. Kadar globulin serum dari sampel yang telah diperiksa memiliki kadar terendah 1,6 g/dL dan tertinggi 5,1 g/dL dengan rata-rata 2,8 g/dL. Dari hasil penelitian kadar globulin serum sapi bali pascatransportasi terhitung lebih rendah dari kadar normal sapi ras lain.
Jenis Cacing dan Prevalensi Infeksi Trematoda pada Gajah Sumatera di Tempat Penangkaran Desa Bakas dan Desa Taro, Bali
Authors: Wisana Kadek Adya Arsa , Oka Ida Bagus Made , Suratma Nyoman Adi
Published: May 2022

Gajah Sumatera merupakan satwa asli dari Pulau Sumatera yang keberadaan populasinya terancam punah. Gajah Sumatera rentan terhadap penyakit parasit seperti cacing, yang dapat hidup sebagai parasit pada hewan dan manusia. Penelitian ini bertujuan untuk mengetahui jenis cacing Trematoda pada gajah sumatera di Bakas Elephant Tour dan Taro Elephant Safari Park, Bali. Sampel feses yang digunakan sebanyak 39 yang terdiri dari 8 sampel dari Bakas Elephant Tour dan 31 sampel dari Taro Elephant Safari Park. Identifikasi telur cacing dilakukan dengan pemeriksaan feses menggunakan metode Parfitt and Banks dengan modifikasi. Jenis cacing yang ditemukan berdasarkan hasil pemeriksaan feses adalah cacing kelas Trematoda yaitu Paramphistomum sp. dan Fasciola sp. Hasil penelitian menunjukkan bahwa prevalensi infeksi Trematoda pada gajah sumatera di Bakas Elephant Tour dan Taro Elephant Safari Park adalah 17,94%. Berdasarkan lokasinya, prevalensi di Bakas adalah 0% dan di Taro Elephant Safari Park adalah 22,58%.