bluuebunny/crossref_metadata_2025 huggingface dataset:
Promising Strategies to Support COVID-19 Vaccination of Healthcare Personnel: Insights from the VHA National Implementation
Authors: Giannitrapani Karleen F. , Brown-Johnson Cati , Connell Natalie B. , Yano Elizabeth M. , Singer Sara J. , Giannitrapani Susan N. , Thanassi Wendy , Lorenz Karl A.
Published: September 2021

Background
As of August 2021 up to 30% of Americans were uncertain about taking the COVID-19 vaccine. Some healthcare personnel (HCP) also delayed or declined vaccination.
Objective
Identify barriers and facilitators of Veterans Health Administration (VHA) HCP vaccination program
Design:
Key informant interviews with employee occupational health (EOH) providers
Participants:
38 VHA EOH providers representing 26 of VHA’s regionally diverse healthcare systems.
Approach:
Thematic analysis elucidated 5 key themes, and specific strategies recommended by EOH
Key Results:
Implementation themes included: 1) Leverage diverse skillsets through multidisciplinary effort, specifically COVID-19 vaccination teams with clear goals/roles. 2) “Focus like a laser”: invest in processes and align resources with priorities, including specific strategies of: creating detailed processes, eg. logistics plan to prevent wastage and allocate excess vaccine doses; addressing time trade-offs for personnel involved in vaccine clinics by suspending everything non-essential; designating process/authority to shift personnel where needed; and proactively involving leaders to support resource allocation/alignment. 3) Expect and accommodate vaccine buy-in occurring over time, including specific strategies of: preparing for some HCP slow buy-in; aligning buy-in facilitation with identities and motivation; encouraging word-of-mouth and hyper-local testimonials. 4) Overcome misinformation through trustworthy communication, with specific strategies including: tailoring communication to individuals and addressing COVID vaccines “in every encounter”; leveraging proactive institutional messaging (e.g., townhalls, Q&As) to reinforce information; inviting bi-directional conversations about hesitancy. 5) Use existing and newly developed communication channels to foster sharing and learning across teams and sites, eg. a national VHA EOH listserv.
Conclusions
Expecting deliberation allows systems to prepare for complex distribution logistics, and conversations that are trustworthy, bi-directional, and identity-aligned - overall supporting mandate goals. Ideally, organizations 1) provide time for conversations about vaccines; those conversations would 2) address individual concerns and foster bi-directional shared decision-making, 3) be informed by identity-based motivation, and 4) delivered by identity-concordant individuals.
Application of interdisciplinary collaborative hospice care for terminal geriatric cancer patients: A prospective randomised controlled study
Authors: LIU Yong , Shen Yin , Pan Qinghua , Zou Houwen , Huang Zuochao , Liu Zhiping , Wang Xiaomao
Published: September 2021

Background
Hospice care (HC) is specialized medical care for terminal patients who are nearing the end of life. Interdisciplinary collaborative hospice care (ICHC) is where experts from different disciplines and patients/caregivers form a treatment team to establish shared patient care goals. However, the ICHC efficacy has not been frequently studied in the terminal geriatric cancer patients (TGCPs) population. This study aimed to gain insight into ICHC provided to TGCPs by an ICHC team and identify factors to ameliorate multidimensional HC.
Methods
166 TGCPs were equally divided into ICHC group and life-sustaining treatments (LSTs) group as control. The scores of these questionnaires [such as EORTC QLQ-C30, Hamilton Anxiety Scale], the median survival time (MST), symptoms improvement, the median average daily cost of drugs (MADDC), the median total cost of drugs (MTDC) in the last 2 days, and medical care satisfaction were observed in both groups.
Results
After treatment, the emotional function and symptoms in the ICHC group were statistically higher improvement than those in the LSTs group (P < 0.05). The MADDC and the MTDC in the last 2 days were statistically lower in the ICHC group than those in the LSTs group (P < 0.01). In addition, the overall satisfaction situation and the cooperation ability in the ICHC group were statistically higher than those in the LSTs group (P < 0.01).
Conclusion
The ICHC could provide TGCPs with coordinated, comfortable, high-quality, and humanistic care.
Neuropathology, Genetics and Biomarkers of Synucleinopathies
Authors: Koga Shunsuke , Sekiya Hiroaki , Kondru Naveen , Ross Owen , Dickson Dennis
Published: September 2021

Synucleinopathies are clinically and pathologically heterogeneous disorders characterized by pathologic aggregates of α-synuclein in neurons and glia, in the form of Lewy bodies, Lewy neurites, neuronal cytoplasmic inclusions, and glial cytoplasmic inclusions (GCIs). Synucleinopathies can be divided into two major disease entities: Lewy body disease (LBD) and multiple system atrophy (MSA). Common clinical presentations of LBD are Parkinson's disease (PD), PD with dementia (PDD), and dementia with Lewy bodies (DLB), while MSA has two major clinical subtypes, MSA with predominant cerebellar ataxia (MSA-C) and MSA with predominant parkinsonism (MSA-P). There are currently no disease-modifying therapies for the synucleinopathies, but elucidation of genetics and mechanisms of α-synuclein conversion to pathologic oligomers and insoluble fibrils offer hope for eventual therapies. It remains unclear how α-synuclein can be associated with distinct cellular pathologies (e.g., Lewy bodies and GCI) and what factors determine neuroanatomical and cell type vulnerability. Accumulating evidence from in vitro and in vivo experiments suggests that α-synuclein species derived from LBD and MSA are distinct "strains" having different seeding properties. Recent advancements in in vitro seeding assays, such as real-time quaking-induced conversion (RT-QuIC) and protein misfolding cyclic amplification (PMCA), not only demonstrate distinct seeding activity in the synucleinopathies, but also offer exciting opportunities for molecular diagnosis using readily accessible peripheral tissues. Cryogenic electron microscopy (cryo-EM) structural studies of α-synuclein derived from recombinant or brain-derived filaments provide new insight into mechanisms of seeding in synucleinopathies. In this review, we describe clinical, genetic and neuropathologic features of synucleinopathies, including a review of classification and staging schemes for LBD. We also review evidence supporting the existence of distinct α-synuclein strains in LBD and MSA.
Records of plutonium isotopes in marine sediments from the southern Gulf of Mexico
Authors: Alvarado Jose A. Corcho , Diaz-Asenciuo Misael , Röllin Stefan , Herguera Juan Carlos
Published: September 2021

Here we report on new data on plutonium (Pu) isotopes to elucidate activity concentrations, inventories, sources and their transport from the ocean surface to the sea floor from a collection of deep-sea sediment cores (depths ranging from 257 to 3739 m) in the Gulf of Mexico (GoM). Sediment cores collected from the continental shelf and upper slope region of the GoM consistently showed 240Pu/239Pu ratios of 0.15 to 0.26 and Pu-inventories ranging from 15 to 35 Bq m− 2. Inventories and ratios are consistent with global fallout Pu for this tropical region. In the continental shelf and upper slope regions, higher particle concentrations close to the margins favor significant scavenging and removal of Pu from the water column; in contrast with the deep-sea cores that show low 240Pu/239Pu ratios (0.07–0.13) and a much lower Pu inventory (< 7 Bq m-2) implying a small fraction of the expected global fallout inventory has reached into the lower slopes and abyssal plain of the GoM. Low values and a progressive decrease of 240Pu/239Pu ratios and Pu inventories with increasing water depth have been previously reported for the GoM. The low Pu ratios indicate that Nevada tests fallout was an important source of Pu to deep-sea sediments, and that this source was likely more efficiently removed from the water column than global fallout Pu. Analysis of Pu isotopes in two sediment traps from the upper slope regions show 240Pu/239Pu ratios comparable to the ones observed in the global fallout. These results indicate that global fallout Pu is currently the main source of Pu in water column particles. Therefore, a significant fraction of global fallout Pu must still be present; either in a dissolved phase, or as biologically recycled material in the water column, or scavenged on the shelf and shelf break. Our results bring to light important questions on the application of Pu isotopes to establish sediment chronologies, since these radionuclides are shown to be tracers of bioturbation rather than accumulation processes in deep-sea sediments of the GoM, similar to previously reported results from excess 210Pb.
High precision machining of a displacement sensor for helicoidal motions
Authors: ELRAWASHDEH Zeina , REVEL Philippe , PRELLE Christine , LAMARQUE Frédéric
Published: September 2021

This research study presents the design and the high precision manufacture procedure of a fiber-optic displacement sensor. It is composed of two fiber-optic probes associated with a structure of a cones’ grating. The sensor is characterized by its ability to measure the linear displacement for an axis performing a helicoidal motion. This motion has been demonstrated on a high precision lathe; where the spindle provided the rotational motion, associated to a translational motion on the linear stage. This allowed to obtain the two simultaneous motions. The displacement of the translational stage is measured by the sensor in real time.Firstly, a highly precise geometric model of the reflector part for the sensor was developed. This model provided a specific geometry for the cones-assembled grating, which has been precisely manufactured. The geometric parameters and the surface characteristics of each step in the fabricated grating were both identified in situ on the lathe. The agreement between simulation and experimental results is excellent. The performances of the fiber-optic displacement sensor were identified in-situ on the lathe. The analysis of the voltage output signals from the two fiber-optic probes is used to measure the grating displacement. The unbalanced rotation due to non-centered axes was also characterized. The sensor provided a micrometric resolution, on a measurement range of more than one centimeter.
DEMOCRATIC PATTERNS IN SUB-SAHARAN AFRICAN STATES TODAY
Authors:   Freelance Researcher In The Democratic Processes In The Sub-Saharan Region., Miji Ayeah Ernest
Published: September 2021

Many writers and political commentators erroneously consider the sub-Saharan region as a homogeneous region and as such talk of an African democracy. This article has come out with various patterns that can be observed today across the sub-Saharan region. The democratic snapshots taken show variants emanating from the 4 sub-regions, a states colonial history, the possession of oil, states suffering sanctions and the longevity of the president. Two democratic indexes Freedom House and Mo Ibrahim Index of Governance form the bases for the measurement of democracy in these states. In the majority of cases, both indexes have somehow given the same outlook of a countrys democracy thereby reinforcing the conclusions drawn in this article. In order to proceed to the democratic patterns of these states, prior analyses of the decolonization and the struggle for influence by the Superpowers in the sub-Saharan region was done. These earlier dynamics help us to understand the present democratic patterns better.
SURVEY OF ETHNO MEDICINAL PLANT SHOWING WOUND HEALING ACTIVITY
Authors:   Faculty of Pharmaceutical Science, Assam down town University, Panikhaiti, Guwahati, Assam., Borsaikia Ansumita , Sen Saikat ,   Faculty of Pharmaceutical Science, Assam down town University, Panikhaiti, Guwahati, Assam., Gogoi Pal ,   Faculty of Pharmaceutical Science, Assam down town University, Panikhaiti, Guwahati, Assam., Kumar Dev Biplab ,   Faculty of Pharmaceutical Science, Assam down town University, Panikhaiti, Guwahati, Assam.
Published: September 2021

In most recent couple of a few years, there has been a unprecedented advancement in understanding the biochemical and cell occasions of typical injury recuperating or wound healing. Healing is survival mechanism and represents a trial to take care of normal complex body part and performance.Wound healing could be a process by which tissue regeneration occurs. Healing of wounds, either accidental or surgical interventions, involves complex activities of blood cells, tissues, soluble mediators, cytokines and several other growth factors. This increased cellular activity of damaged tissue enhances metabolic demands and active drug therapy. The main objective of treating a wound is to either shorten the time required for healing process or to reduce the undue effects. Plants because of presence of assorted valuable active phytoconstituents have immense potential for management and treatment of wounds over the years. All the Traditional systems of medicine, Ayurveda, Siddha and Unani describe applications of medication of plant, mineral and animal origin to treat and heal wounds. Herbal drugs induce healing and regeneration of lost tissue by number of mechanisms. Due to their traditional applicability, affordability and safety plants gained a reputed position within the world of wound management and repair.The present review is a trial to focus on various Indian ethno-medicinal plants which are to be scientifically proved for the treatment of wounds. Beside this review also emphasis on normal wound healing process, pharmacological activities and role of plants in wound management and parameters accustomed assess wound healing.
SMS CLASSIFICATION: CONJOINT ANALYSIS OF MULTINOMIAL NAIVE BAYES APPLICATION
Authors:   Department of Information Technologies, Faculty of Engineeringamd Natural Sciences, International Burch University., Burgic Vedad , Keco Dino ,   Department of Information Technologies, Faculty of Engineeringamd Natural Sciences, International Burch University.
Published: September 2021

Nowadays there are ham and spam messages that are sent to the users via SMS. The aim of this article is to show how machine learning and text processing technologies can be used in order to predict the trustworthiness of SMS messages. The data we are going to use is collected from Kaggle. This study is very important because it helps us to understand how machine learning and text processing can be used in order to predict message trustworthiness. At the time of writing this article, there was not an article explaining how this can be done using the Multinomial Naive Bayes algorithm. The methodology we used in this article consists of dataset collection, data cleaning, data analysis, text preparation, and training model. This will be seen in the methodology section in great detail. At the end of this article, we will show to u the accuracy that we have got when implementing a Multinomial Naive Bayes algorithm for the classification of SMS messages. This study was quite beneficial because anyone can see how Multinomial Naive Bayes algorithm usage can be beneficial in order to predict the trustworthiness of SMS messages.
Ecological drought and its state assessment: a case study in the Yellow River estuary
Authors: Zhang Jinliang , Liu Bojun , Yang Libin , He Liyuan , Cao Xinyi , Shao Guangwen
Published: September 2021

Water cycle has been intensified by global warming, leading to frequent extreme climate events. Drought is an extreme climate phenomenon. Runoff decrease and human water demand increase aggravate the water shortage of regional ecosystems, affecting regional water and land ecosystems and causing ecological drought, river cutoff and water pollution. Finally, the reverse succession and the imbalance of regional ecological structures take place. The clarification of the concept of ecological drought for effective evaluation of regional ecological drought degree has become an urgent important scientific issue to be resolved. Therefore, in this paper, the typical region of the Yellow River estuary was studied for the analysis of characteristics of regional ecological changes and the definition of the concept and connotation of ecological drought. Based on the representative monitoring and early warning indices to ecological drought, the evaluation method and the classification standard of regional ecological drought were proposed. The regional ecological drought includes four levels: I (Severe), II (General), III (Weak) and IV (None). The indicator thresholds of river runoff, biodiversity and vegetation coverage on different ecological drought levels were quantified. The research results can be technically beneficial for the improvement of global ecological drought emergent support capacity and reducing loss due to drought.
Precipitation barycenter and relationship to the spatial distribution of station networks on the Huang-Huai-Hai Plain, China
Authors: Ling Minhua , Han Hongbao , Yu Lili , Tang Shinan
Published: September 2021

A precipitation barycenter reflects the overall spatial distribution and long-term evolution of regional precipitation. Understanding the changes in precipitation barycenter has significant implications for drought management, flood control, and water resource management. This paper analyzed the distribution and transfer of monthly, interannual, and interdecadal precipitation barycenter on the Huang-Huai-Hai Plain (‘3H’ Plain). We also discussed the influence of the station network spatial distribution on the changes in precipitation barycenter. The results were as follows: (1) The trajectory of the monthly precipitation barycenter on the ‘3H’ Plain was generally ‘8’-shaped. The rainy and dry season precipitation barycenters were located in the upper and lower parts of the ‘8’-shaped, respectively. (2) In the past 60 years, the interannual precipitation barycenter had a trend of moving southwest, but the trend was not apparent. (3) Station network density and uniformity dominated the changes in precipitation barycenter, showing positive correlations. When the station network density was large and exceeded a certain range, the influence of station network density on the changes in precipitation barycenter decreased.
BDZs, Designer BDZs and Z-drugs: Pharmacology and Misuse Insights
Authors: Zaami Simona , Graziano Silvia , Tittarelli Roberta , Beck Renata , Marinelli Enrico
Published: September 2021

:

Benzodiazepines (BZDs) are a widely prescribed class of sedative-hypnotics compounds for the treatment
of a broad range of conditions as anxiety and obsessive-compulsive disorders, phobias, sleep-related
problems associated with insomnia, and for the management of alcohol and GHB withdrawal. Zolpidem, zopiclone
and zaleplon, commonly known as Z-drugs, are non-benzodiazepine hypnotic drugs with pharmacology
similar to BDZs. Despite their usefulness, BDZs and Z-drugs present a potential for abuse and dependence.
Moreover, the non-medical use of BDZs is a well-known phenomenon and represents an increasingly widespread
public health problem since it is associated with an elevated risk of serious health consequences or fatal
overdose, especially among specific group of users. The spectrum of BDZs and Z-drugs misuse is extended by
new synthetic BDZs, which may pose high risks to users, since the majority have never undergone clinical
trials or tests and consequently their pharmacology and toxicology are largely unknown.
Insight into the Isolation, Synthesis, and Structure-Activity Relationship of Piperine Derivatives for the Development of New Compounds: Recent Updates
Authors: Afreen  , Salahuddin  , Mazumder Avijit , Joshi Sagar , Kumar Rajnish , Yar Mohammad Shahar , Ahsan Mohamed Jawed
Published: September 2021

Currently, black pepper commands the leading position among all the spices as a spice of
great commercial importance in all the world trade and finds its way into the dietary habits of millions
of people worldwide. Black pepper is biologically known as Piper nigrum and contains piperine as
the main active chemical constituent. This paper highlights various general methods for extracting
piperine from the crude drug such as maceration extraction, hydrotropic extraction, accelerated solvent
extraction, thin-layer chromatography, and extraction with ethanol & dichloromethane Ionic
fluid-based ultrasonic-assisted extraction, etc. In this review, piperine and its analogs exhibit numerous
pharmacological activities and synthetic schemes of insecticidal activity, anti-cancer activity,
anti-inflammatory activity, anti-diabetic activity, anti-hyperlipidemic activity, antifungal activity,
narcotic activity, etc. and its structure-activity relationship. The biochemistry of piperine has also
been summarized in the presented article. This very exhaustive review details the complete information
about piperine, its derivatives, and further processing. Furthermore, the current study summarises
recent research that has linked piperine to its use as a treatment for a variety of ailments.
Spine Infections: The Role of Fluorodeoxyglucose Positron Emission Tomography (FDG PET) in the Context of the Actual Diagnosis Guideline
Authors: Boriani Luca , Zamparini Eleonora , Albrizio Mauro , Serani Francesca , Ciani Giovanni , Marconi Lorenzo , Vommaro Francesco , Greggi Tiziana , Fanti Stefano , Nanni Cristina
Published: September 2021

:

Spondylodiscitis is an infectious process that requires numerous health care professionals to be clearly diagnosed and eventually successfully treated. It implies a variety of microbiological agents and conditions; during the diagnostic workup, it is difficult to correctly identify them, and the clinician has to rapidly choose the correct treatment to avoid permanent injuries to the patient. In this context, we conducted a review to better understand the most suitable use of Positron Emission Tomography with 18-Fluoro-deossi-glucose (FDG PET) in a patient suspected of spondylodiscitis, based on current guidelines and literature.. We wanted to review the role of FDG PET in the spondylodiscitis diagnosis and follow up in the context of the current guidelines.
Knowledge, Perceptions, and Attitudes Regarding COVID-19 and Infection Control Measures Against it among Dental Students in Saudi Arabia
Authors: Alharbi Tahani M. , Alharbi Afrah M. , Khayyat Rafal K. , Aldaadi Jawaher B. , Afifi Ibtesam K.
Published: September 2021

Background

Coronavirus disease (COVID-19) is a highly infectious disease caused by an RNA virus named SARS CoV2. The increased risk of infection by this virus among dental students necessitates updated knowledge and highlights their important role in preventing and controlling its transmission.

Objective:

This study aims to assess knowledge, perceptions, and attitudes regarding COVID-19 and infection control measures among dental students in Saudi Arabia.

Methods:

A cross-sectional study was conducted among dental students in different Saudi universities using an online self-administered questionnaire. It gathered data on students’ demographic information, knowledge of COVID-19 and infection control measures, risk perception and attitudes toward the disease, and their preparedness for treating infected patients.

Results:

A total of 327 dental students responded to the questionnaire. Of these students, 92.4% had received training in infection control in dental practice, but only 24.2% had attended training regarding COVID-19. The majority of students had adequate knowledge regarding the modes of transmission and the common symptoms of COVID-19, with statistically significant total mean knowledge scores among students in different academic years (p<0.05). A large percentage of the students (92.7%) agreed that the use of rubber dams or high-volume saliva ejectors could reduce the possibility of transmitting infection. However, 58.4% of the students disagreed that intraoral dental radiographs should be avoided to reduce the possibility of transmitting infection.

Conclusion:

Although knowledge of and risk perception concerning COVID-19 among students is good, additional training sessions integrating recent international guidelines for infection control are required to update their knowledge and achieve safe dental practice.
Residual Dentin Thickness in Bifurcated Maxillary Premolars after Cervical Preflaring Preparation: A CBCT Analysis
Authors: Filho Gilberto Siebert , Guedes Orlando Aguirre , Pereira Thiago Machado , Miranda-Pedro Fabio Luís , Aranha Andreza Maria Fábio , de Oliveira Helder Fernandes , Pécora Jesus Djalma , Borges Álvaro Henrique
Published: September 2021

Objective:

This study evaluated the residual dentin thickness (RDT) of maxillary premolars after the use of different cervical preflaring (PF) drills by using cone-beam computed tomography (CBCT).

Methods:

Eighty bifurcated maxillary premolars were accessed and randomly divided into 5 groups (n=16). PF was performed with Gates-Glidden #1, #2, and #3 (group 1), Largo #1 and #2 (group 2), and LA Axxess #20/.06 (group 3), #35/.06 (group 4), and #45/.06 (group 5). CBCT images were acquired before (preoperative) and after (postoperative) PF. Initial and final cervical dentin thickness was measured at the buccal, palatal, mesial, and distal aspects, 0.5 mm coronally to the furcation, on both buccal and palatal roots, using CBCT’s image analysis software. The percentage of removed dentin after PF preparation was also calculated. Data were analyzed using ANOVA followed by Tukey’s test at a significance level of P < 0.05.

Results:

No statistically significant differences were found among the groups for preoperative or postoperative RDT (P > 0.05). LA Axxess #20/.06 (group 3) removed significantly less cervical dentin at all root canal aspects on both buccal and palatal roots. The mesial aspect of the buccal root and distal aspect of the palatal root were significantly reduced after the use of LA Axxess #45/.06 (group 5) and Largo #1 and #2 drills (group 2), respectively (P < 0.05).

Conclusion:

PF in bifurcated maxillary premolars should be performed with LA Axxess instrument #20/.06. The use of Gates-Glidden #1, #2, and #3, Largo #1 and #2, and LA Axxess #45/.06 drills should be done with caution.
The Application of Pendulum as a Space Regainer in Orthodontic Treatment
Authors: Halim Himawan
Published: September 2021

Background:

The process of distalization in orthodontic treatment is often very difficult. The most common method is the use of cervical headgear. However, due to poor patient compliance, it leads to poor treatment outcomes. Treatment alternatives that require minimal compliance include Jones jig, magnets, and pendulum.

Objective:

This study aimed to perform distalization of a maxillary molars on a bilateral Class II molar relationship patient with a crowded maxillary arch.

Case Report:

A 10-year-old female with a Class II molar relationship, bilateral posterior crossbite, and nonerupted upper canines was treated with a rapid palatal expander (RPE), pendulum appliance, and fixed appliance. The crowding in the maxillary arch and spacing in the mandibular arch were eliminated, and transverse discrepancies were corrected.

Conclusion:

Pendulum appliance is very effective in creating spaces for the eruption of canines and ectopic premolars. Pendulum appliances have been introduced for a long time and have proven successful for molar distalization and space regainer and require minimal patient cooperation. Like other distalization appliances, distal tipping of the molars and mesial movement of the premolars could be observed.
Ergenlerde, aktif ve pasif sigara içiminin solunum fonksiyon testleri üzerine etkisi
Authors: Sevim Meliha , Atay Gürkan , . Abdullah Yağci , Topuz Melike , Özdemir Arslan Öznur
Published: September 2021

Amaç: Bu çalışmanın amacı ergenlerde aktif ve pasif sigara içiminin solunum fonksiyonları üzerine etkisini belirlemektir. Gereç ve yöntem: Bu çalışma, Haziran 2013-2015 tarihleri arasında, Ankara Eğitim ve Araştırma Hastanesi Çocuk Polikliniğine başvuran ergenler dahil edildi. Olguların ve ailelerinin sosyodemografik özelliklerini içeren anket formu ebeveynler tarafından dolduruldu. Olgular, aktif sigara içenler, pasif sigara içenler ve hiç içmeyenler olmak üzere üç gruba ayrıldı. Tüm olguların volumetrik spirometre ile solunum fonksiyon testleri yapıldı. Bulgular: Çalışmaya alınan toplam 222 ergenin yaş aralığı 11-17 yaş (median:15 yaş) olup 102’si (%45,9) erkek ve 120’si (%54,1) kızdı. Aktif sigara içenler %29,7 [n= 66, median 16 yaş, 42 erkek (%64) ve 24 kız (%36)], pasif sigara içenler %55,4 [n= 123, median 14 yaş, 52 (%42,3) erkek ve 71 kız (%57,7)] ve hiç içmeyenler %14,9 [n=33, median 14 yaş, 8 erkek (%24,2) ve 25 kız (%75,8)] idi. Pasif sigara içenlerin FEF25-75 ve FEV1 değerleri aktif sigara içenlere göre farklı bulunmadı. Ancak, hiç içmeyenlerle karşılaştırıldığında anlamlı daha düşüktü (sırası ile p=0,049; p=0,003). Pasif sigara içen grubun FVC değerleri aktif sigara içen ve hiç sigara içmeyen gruba göre anlamlı olarak düşük saptandı (sırası ile, p=0,020; p=0,010). Sonuç: Ergenlik döneminde sigara içme oranı yüksek saptandı (%29,7). Pasif sigara içen grubun solunum fonksiyon testlerinin anlamlı düşük çıkması, sigaraya maruziyet oranının, maruziyet tipinden (aktif/pasif) daha etkili bir faktör olduğu kanısını ortaya koymuştur.
Evaluation of Children with Extremity Fracture Occurred as a Result of Motor Vehicle Injury
Authors: Fidancı İlknur , Derinöz-güleryüz Okşan , Oğuz Işıl Seren
Published: September 2021

Aim: The aim of the study was to examine and evaluate patients with extremity fractures who admitted to the Pediatric emergency service due to a motor vehicle accident, whether there was any accompanying additional organ injury, and fracture patterns according to the severity of the trauma.
Material and Method: The study was conducted between January 2015 and 2020 retrospectively. Relevant data were analyzed with IBM SPSS V23 statistics.
Results: Of the 205.710 patients who admitted to Pediatric emergency service in the course of this study, 1.378 (0.66%) experienced motor vehicle injuries. 161 (0.08%) of these cases were evaluated on the grounds of extremity fractures. Mean age of the cases were 133 months (minimum: 3, maximum: 2018 months) and 90 (56%) cases were male. Trauma type was mostly outside-vehicle traffic accident (50%). 55% of the cases were severe mechanism of injury. The most common lower extremity fracture type was the tibia (26%) fracture. The most common fractures in the upper extremity were humerus (16%) and radius (16%) fractures. Of the patients with pelvis fracture, 65% had other types of organ injuries (p<0,05). Surgical treatment was admitted to 68% of those with femoral fractures and 43% of those with tibia fractures (p <0.05). While lower extremity fractures were more common in outside-vehicle traffic accident (66%) and motorcycle accident (60%), upper extremity fracture was more common in intra-vehicle traffic accident (54%) (p <0.05).
Conclusion: Since the literature evaluating the extremity fractures in motor vehicle accidents is very limited, relevant data are also very limited. Extremity fractures that occur especially after motor vehicles are an important cause of injuries and deaths, and impose a heavy burden upon both families and the government in terms of hospital stay and hospital costs.
Clinical application in sexual orientation
Authors: Binti Mustamam Dayana Musfirah , A/L Rajathurai Jivanishenthiran , Gusdian Putri Milenia , Binti Nasir Khan Zaireen Zulaika
Published: September 2021

When we talk about sexual orientation the first think that come into our mind is on the individual’s sexual identity in relation to the gender. But, we should know that sexual orientation and sexual identity are different. Sexual orientation is also generally defined in terms of several groups, such as heterosexuals, where there is psychological, romantic or sexual attraction towards the opposite sex, homosexuals like gay or lesbian with a psychological, social or sexual preference towards the same sex. This paper is one of the assignments in the Multicultural Counseling's subject, which discusses several cases that discuss about client's sexual orientation, then the causes and impacts of the social environment on their sexual orientation. As we know, this problem is a thing that not consider in majority of environment. Also, we convey how future counselors should respond and behave when dealing with sexual orientation clients.Keywords: sexual orientation; sexual identity; future counselor
Body Image and Disordered Eating Among LGBTQ+ University Students and Recent Graduates in Rural Appalachia: A Thematic Analysis
Authors: Savitsky Devyn
Published: September 2021

LGBTQ+ university students and recent graduates of a large rural Appalachian institution were interviewed for an exploratory thematic analysis on body image and disordered eating behaviors. While participants noted an overall sense of comfortability in the university setting, there were varying obstacles associated with navigating intersecting identities and physical presentation that were noted in the data. Excerpts from participant interviews were coded into five unique themes: (1) feeling “othered”/different from peers as well as fellow LGBTQ+ community members, (2) seeking comfortability with body/self, (3) facing stereotypes and image expectations based on presumed gender identity and/or sexual/affectional orientation, (4) general experiences as an LGBTQ+ community member in a rural university town, and (5) seeking increased support from the university. This study concludes that significant challenges related to body image are exacerbated by common experiences as a person in the LGBTQ+ community.
Career guidance conceptualization to improve career adaptability for generation z
Authors: Nadya Aisha , Farozin Muh
Published: September 2021

Generation Z will control 20% of the workplace. Every generation has a different approach to work and the workplace. Z generation needs to have career adaptability to anticipate problems such as worries about not getting a job and a lack of understanding about the desired field of work.  The research aims to explore and create a solid theoretical foundation for designing a career guidance model to increase the adaptability of Generation Z’s career. The research uses library research methods sourced from books and literature on 1) career adaptability, 2) understanding generation Z, 3) counselling guidance models in the revolutionary era 4.0. The comparison between Generation Z characteristics and the dimensions of career adaptability, the primary need of Generation Z is career control. Career guidance services for Generation Z can be in the form of 1) coaching, 2) workshops, 3) inspirational content through social media, 4) internship programs.
Level of Academic Stress for Students of Guidance and Counseling at Semarang State University during the Pandemic
Authors: Octasya Tivanny , Munawaroh Eem
Published: September 2021

Academic stress is a subjective perception of an academic condition or a response experienced by students in the form of negative physical reactions, behaviors, thoughts, and emotions that arise due to school or academic demands. During a pandemic Covid 19 most of earning activities becomes online. The aim of this research is to determine the level of academic stress among students in Guidance and Counseling Department, Semarang State University during the pandemic. The method used is descriptive qualitative research. This research conducted interviews to collect data by using purposive sampling. The results  show that students experience symptoms of academic stress symptoms that affect their physical, emotional, behavioral, and thoughts as well as several factors that influence academic stress both in themselves (internally) and in the environment and circumstances (externally). The conclusion of this study is the respondents' stress level is quite high or increases when they get assignments from the lecturers.
The effectiveness of using educational cinema techniques to increase students’ self-confidence: An experimental research
Authors: Utomo Prio , Maratus Sholihah
Published: September 2021

This research is motivated by the problem of low self-confidence of students. The purpose of this study was to test the effectiveness of educational cinema techniques as a medium to increase students' low self-esteem. The research design used pre experimental research with one group pretest and posttest design. The research subjects were 16 students of class VIII SMPN 6 Malang, the subjects were selected using purposive sampling technique. Data collection used (1) self-confidence scale; (2) experimental guidelines and (3) observation guidelines. Data analysis used descriptive and statistical analysis (Wilcoxon signed rank test). The results of data analysis produce that H0 is rejected and H1 is accepted, this means that there is a significant increase in student self-confidence after being given educational cinema techniques. The findings of the study show that there are differences in the improvement of students 'self-confidence between before (pretest) and after (posttest) being given educational cinema techniques, thus the results of the study concluded that educational cinema techniques were effective in increasing students' self-confidence.
Profile of self-awareness among junior high school students
Authors: Lailatussaidah Lely , Isti’adah Feida Noor Laila , Nugraha Agung
Published: September 2021

The purpose of this study was to describe a profile of self-awareness among students in junior high school in the city of Tasikmalaya. Research grounded by the similarities in the tendency of the problems that occur about excessive anxiety among students. The data analysis technique in this study used inferential statistics with random sampling and a total population of 262 students. The results showed that the self-awareness of subject research was in the high category with an average of 75.47%. This shows that most of the subject research have achieved maximum self-awareness in several aspects and indicators, including the achievement of student self-awareness, namely having an understanding of strengths and weaknesses, being able to develop themselves for the desired achievement and have the confidence to voice their opinions.
Ecological Counseling as an Integrative Cognitive Complexity Intervention Framework for Students with COVID-19 Pandemic-Caused Mental Health Challenges
Authors: Gunawan Nanang E. , Foreman Tamarine
Published: September 2021

This article aims to present a practical conceptual perspective on ecological counseling as a theoretical framework for counselors' integrative cognitive complexity to work with students who experience mental health challenges caused by the COVID-19 pandemic. The transition of educational activities into virtual learning has caused various challenges for students worldwide that risk their mental health. Indonesia is one of the countries implementing virtual learning for more than a year with various social, technical, and environmental obstacles. Besides the benefit of distanced learning, this online learning model has widely caused mild to severe anxiety among students. Although researchers have investigated the impacts of virtual learning on mental health problems, the intervention strategies to help students with mental health issues remain lack attention. Ecological counseling has been known for its principles of seeing individuals' mental health issues involving a broader milieu that allows counselors to understand clients according to their contextual living systems. This framework offers a culturally sensitive perspective to help counselors withdraw appropriate and best available information for intervention purposes. This article also includes an application illustration of the ecological counseling framework in the Indonesian community as a practical guideline. It is expected that this article provides academic supports for academics to work with students dealing with their mental health challenges during this pandemic adhere to the counselors' integrative cognitive complexity functions.
Promoting students’ tolerance awareness in the context of peace education through Wayang Golek
Authors: Harjianto Feri Henri , Handarini Dany Moenindyah , Setiyowati Arbin Janu
Published: September 2021

Tolerance awareness is one of important aspect to realizing peace education that train students to avoid of using violence. This study aims to represent the results of the tolerance awareness training guide using “wayang golek” as a media to realize peace education by using indigenous heritage that has been tested for acceptability standards.  Research and development model used in this study which has been modified according to the needs and deficiency of researchers in the field, so that it consists of six stages: preliminary study, planning, product making, product testing, product revision, and final product. The assessment that used in this study was adjusted to "Standards for Evaluation of Educational Programs, Projects, and Materials by the joint committee" which involves two experts in the field of guidance and counseling as well as practitioners in the field. The result shows that the guide of tolerance awareness training using “wayang golek” as a media fulfilling the acceptability standards. Recommendation for further researchers to test the effectiveness of the product using experimental method.
Капиллярно-волновой варп-двигатель
Authors: Александров В.А.
Published: September 2021

The generation of surface water flow in channels with sources and resonators of capillary oscillations is detected and investigated. Moving devices with a capillary-wave accelerator of the surface fluid flow are demonstrated. The surface flow of liquid in the channel is generated due to the local deformation of the liquid surface by capillary vibrations and the formation of an excess liquid surface on average near the source and the transport of this surface by waves.
Два вида структуры плазменного канала в импульсном разряде высокого давления в цезии
Authors: Бакшт Ф.Г. , Лапшин В.Ф.
Published: September 2021

Simulation of the pulse-periodic high pressure cesium discharge is performed on the basis of equations of radiative gas dynamics. It is shown that in the discharge it is possible to implement two different types of structure of the plasma channel. At the beginning of the current pulse, the plasma discharge channel has a centered structure. At the same time, most of the plasma is concentrated near the discharge axis. The concentration of charged particles decreases along the radius.Then, if the current amplitude is large enough, during the plasma heating process, a transformation from the centered to the shell structure of the channel occurs. In this case, most of the plasma is concentrated on the periphery of the discharge and its concentration increases along the radius from the axis to the walls of the tube. It is shown that the transition from one channel structure to another occurs at a time when the specific heat capacity of the plasma near the axis reaches a deep minimum corresponding to a completely single ionized e-i plasma.
Излучение дробного осциллятора
Authors: Рехвиашвили С.Ш. , Псху А.В. , Маргушев З.Ч.
Published: September 2021

The spectral energy density of the oscillator radiation is calculated in the dipole approximation. The oscillator motion is described by an equation with fractional integro-differentiation. The fractional oscillator model can describe various types of radiation, including those with a nonexponential relaxation law. Found the shape of the spectral line of radiation. The obtained result is compared with the classical Lorentzian spectrum and experimental emission spectra of monochromatic and phosphor LEDs. The order of fractional integro-differentiation in the model sets the magnitude of the broadening of the radiation spectrum.
A Deep Learning Approach to Refine the Identification of High-Quality Clinical Research Articles From the Biomedical Literature: Protocol for Algorithm Development and Validation
Authors: Abdelkader Wael , Navarro Tamara , Parrish Rick , Cotoi Chris , Germini Federico , Linkins Lori-Ann , Iorio Alfonso , Haynes R Brian , Ananiadou Sophia , Chu Lingyang , Lokker Cynthia
Published: September 2021

Background

A barrier to practicing evidence-based medicine is the rapidly increasing body of biomedical literature. Use of method terms to limit the search can help reduce the burden of screening articles for clinical relevance; however, such terms are limited by their partial dependence on indexing terms and usually produce low precision, especially when high sensitivity is required. Machine learning has been applied to the identification of high-quality literature with the potential to achieve high precision without sacrificing sensitivity. The use of artificial intelligence has shown promise to improve the efficiency of identifying sound evidence.

Objective

The primary objective of this research is to derive and validate deep learning machine models using iterations of Bidirectional Encoder Representations from Transformers (BERT) to retrieve high-quality, high-relevance evidence for clinical consideration from the biomedical literature.

Methods

Using the HuggingFace Transformers library, we will experiment with variations of BERT models, including BERT, BioBERT, BlueBERT, and PubMedBERT, to determine which have the best performance in article identification based on quality criteria. Our experiments will utilize a large data set of over 150,000 PubMed citations from 2012 to 2020 that have been manually labeled based on their methodological rigor for clinical use. We will evaluate and report on the performance of the classifiers in categorizing articles based on their likelihood of meeting quality criteria. We will report fine-tuning hyperparameters for each model, as well as their performance metrics, including recall (sensitivity), specificity, precision, accuracy, F-score, the number of articles that need to be read before finding one that is positive (meets criteria), and classification probability scores.

Results

Initial model development is underway, with further development planned for early 2022. Performance testing is expected to star in February 2022. Results will be published in 2022.

Conclusions

The experiments will aim to improve the precision of retrieving high-quality articles by applying a machine learning classifier to PubMed searching.

International Registered Report Identifier (IRRID)

DERR1-10.2196/29398
Modern approaches to the methods and treatment strategy in fractures of the ankle joint with tibiofibular syndesmosis rupture (literature review)
Authors: Chiyzak A.V.
Published: September 2021

A review of the literature has shown that the problem of treatment for fractures of the ankle joint with rupture of the tibiofibular syndesmosis is still far from being solved, as evidenced by the frequency of unsatisfactory results during surgeries — 4.8–36.8 %. In the future, the issue and the need to develop a dynamic fixation device, which is able to duplicate the function lost due to damage to the tibiofibular syndesmosis, remain relevant.