bluuebunny/crossref_metadata_2025 huggingface dataset:
Metastatic renal cell carcinoma of the lumbar spine with long posterior instrumented fusion and repetitive dislodgement of the set screws of the S2 alar-iliac screw
Authors: Yoshida Shinsuke , Iida Shunpei , Akagawa Rei , Oya Soichi , Saita Kazuo , Ogihara Satoshi
Published: December 2023

Background:

S2 alar-iliac screws (S2AIS) are widely used to anchor the pelvis to a lumbar fusion. Here, we report a patient who experienced repetitive dislodgement of the set screws of the S2AIS following a posterior instrumented fusion.

Case Description:

A 68-year-old male presented with an L3 metastasis and L2–L3 subluxation attributed to renal cell cancer. Following an L2–L5 posterior decompression and T9-pelvic fusion utilizing bilateral S2AIS fixation, the set screws of the S2AIS repeatedly dislodged, requiring two additional operations. The final surgery required multiple anchors to the ilium and provided adequate fixation until the patient’s expiration.

Conclusion:

The set screw fixing force was weaker than the fixing force of the S2AIS; multiple iliac anchors effectively salvaged this condition.
Comment favoriser l’apprentissage des sons de l’anglais par de jeunes locuteurs non natifs ?
Authors: EXARE Christelle , VAISSIÈRE Jacqueline
Published: December 2023

Cet article présente la réalisation d’un cours expérimental de prononciation des voyelles et des consonnes de l’anglais en L2, spécialement créé pour les écoliers français âgés de 5 à 9 ans. Le cours, fondé sur les principes de CleanAccent©, est conçu pour un apprentissage phonétique préliminaire à toute acquisition du vocabulaire, visant à éviter la fossilisation d’erreurs de prononciation couramment observées. Après quelques remarques générales sur l’enseignement de l’anglais en France, cet article décrit le but de l’expérience : dix heures offertes en présentiel dans une classe pour un apprentissage complet de tous les phonèmes. Il présente ensuite en détail les stratégies pédagogiques sélectionnées durant ces séances d’entraînement : a) la progression dans les 10 leçons guidée par les oppositions phonologiques à acquérir, b) la représentation de chaque voyelle de l’anglais (API) par une image et par une séquence de gestes, avec l’évitement du recours à l’orthographe, c) un jeu de 20 planches de loto illustrant du vocabulaire répondant à la progression choisie et accessible aux enfants, d) l’utilisation de plusieurs locuteurs pour favoriser la phonologisation, e) des vidéos d’accompagnement sur YouTube, f) des jeux mis en ligne, g) et l’apprentissage passif éveillé. Les ressources, réelles et virtuelles, ont été mises à l’essai en partie dans une école d’Évreux. L’expérimentation mène à de nouveaux projets que nous décrivons à la fin de cet article.
Perception and production of French oral vowels by Japanese-speaking learners: does dialectal variation play a role?
Authors: KAMIYAMA Takeki , KANEDA Jumpei , HAYASHI Ryoko
Published: December 2023

This paper presents a series of studies on the impact of regional variation in L1 (source language) on L2 (target language) pronunciation, focusing on the high back vowel /u/ in French perceived or produced by native speakers of Japanese from the Kanto area (around Tokyo) and the Kansai area (around Osaka). 1) To serve as a base line, the 5 Japanese vowels were pronounced by 11 speakers (5 women and 6 men) from Kansai with no learning experience of French and their first 4 formants were measured to examine their acoustic properties. 2) 25 naïve listeners from Kansai took part in an AXB auditory discrimination task for French vowels including pairs /u/-/y/, /y/-/ø/ and /u/-/ø/; the results were compared with those of Kanto speakers in previous studies. 3) Some Japanese-speaking learners of French (JSL) from Kansai produced the French /u/ with a lower F2 (around 1,000 Hz for men) than typical values observed for learners from the Tokyo area. These results show limited differences for some of the speakers from Kansai compared to the tendency commonly observed with Kanto speakers
AI in Higher Education
Authors: Fowler David S.
Published: December 2023

This scholarly inquiry examines the interplay between artificial intelligence (AI) and academic integrity within higher education. Through a comprehensive synthesis of academic literature, the study delves into the multifaceted implications of AI tools on academic practices, pedagogical approaches, and the evolving landscape of academic integrity within higher education. The findings, derived from an extensive analysis of scholarly works, offer profound insights into the challenges posed by the integration of AI in higher education. The impact on academic dishonesty, the nuances of pedagogical shifts, and the dynamic relationship between students and AI are scrutinized, contributing to a nuanced comprehension of the intricate dynamics within the academy.
Homo- to Co-Polyester Conversion in the Absence of Reagents Fa-cilitated by a Dual Catalytic Process Involving Hydrogen Borrowing
Authors: Rummel Frederik , Anuar Afiq , Qiang Yu , Wehmeyer Frerk-Ulfert , Rohmer Matthias , Vogt Matthias , Haase Frederik , Binder Wolfgang , Saalwächter Kay , Thurn-Albrecht Thomas , Langer Robert
Published: December 2023

A ruthenium-catalyzed hydrogen transfer ester metathesis (HTEM) is reported that allows for the isomerization of a linear polyester such as polycaprolactone (PCL) without the need for any stoichiometric reagent, forming a novel type of co-polyester containing additional hexylene adipate (HA) repeating units. Mechanistic investigations show that the formation of the chemically modified polyester relies on a two-fold catalytic reaction; a HTEM via a hydrogen borrowing process and a concomitant transesterification catalyzed by the base co-catalyst. Evidence is provided that the hydrogen transfer ester me-tathesis proceeds via a reversible aldehyde formation. The described HTEM represents an unprecedented catalyzed hydrogen borrowing process within polymers – and bears significant importance regarding a dynamic post-synthetic modification of polyesters.
Synthesis of peptides by reactive extrusion. Application to the continuous and solventless preparation of aspartame.
Authors: Mohy El-Dine Tharwat , Lavayssiere Matthieu , Adihou Hélène , Subra Gilles , Métro Thomas-Xavier , Ludemann-Hombourger Olivier , Lamaty Frédéric
Published: December 2023

The solventless synthesis of peptides from unactivated amino acids was performed in a twin-screw extruder. The general method was applied to the preparation of dipeptides and tripeptides. Aspartame, a synthetic dipeptide, was also prepared in a continuous mode on large scale.
Computational Prediction of an Antimony-based n-type Transparent Conducting Oxide: F-doped Sb2O5
Authors: Li Ke , Willis Joe , Kavanagh Seán R. , Scanlon David O.
Published: December 2023

Transparent conducting oxides (TCOs) possess a unique combination of optical transparency and electrical conductivity, making them indispensable in optoelectronic applications. However, the heavy dependence on a small number of established materials limits the range of devices they can support. The discovery and development of additional wide bandgap oxides that can be doped to display metallic-like conductivity is therefore necessary. In this work, we use hybrid density functional theory to identify a binary Sb(V) system, Sb2O5, as a promising TCO with high conductivity and transparency when doped with fluorine. We have conducted a full point defect analysis, finding F-doped Sb2O5 to exhibit degenerate n-type transparent conducting behavior. The inherently large electron affinity found in antimony oxides also widens its application in organic solar cells. Following our previous work on zinc antimonate, this work provides additional support for designing Sb(V)-based oxides as cost-effective transparent conducting oxides for a broader range of applications.
Harvesting Chemical Understanding with Machine Learning and Quantum Computers
Authors: Liu Shubin
Published: December 2023

It is tenable to argue that nobody can predict the future with certainty, yet one can learn from the past and make informed projections for the years ahead. In this Perspective article, we overview the status of how theory and computation can be exploited to obtain chemical understanding from wave function theory and density functional theory, and then outlook the likely impact of machine learning (ML) and quantum computers (QC) to appreciate traditional chemical concepts in decades to come. It is maintained that the development and maturation of ML and QC methods in theoretical and computational chemistry represent two paradigm shifts about how the Schrödinger equation can be solved. New chemical understanding can be harnessed in these two new paradigms by making respective use of ML features and QC qubits. Before that happens, however, we still have hurdles to face and obstacles to overcome in both ML and QC arenas. Possible pathways to tackle these challenges are proposed. We anticipate that hierarchical modeling, in contrast to multiscale modeling, will emerge and thrive, becoming the workforce of in silico simulations in the next few decades.
Computational Insights into the Thermophysical, Conformational and Electronic Properties of Diketopyrrolopyrrole and Isoindigo Based Semiconducting Polymers
Authors: Kosar Maryam , Abu-Saleh Abd Al-Aziz , Awada Angela , Vu Susanna , Rondeau-Gagné Simon , Trant John
Published: December 2023

Semiconducting polymers, driving the leading edge of organic electronics and emerging soft technologies, feature a range of key attributes including broad solubility for large-scale solution deposition and charge transport properties comparable to amorphous silicon. The optoelectronic and thermomechanical properties of these π-conjugated materials are fully controllable and tunable through synthetic design, continuously improving organic electronics; however, although semiconducting polymers offer multiple functionalization sites for derivatization, synthetic optimization can be time-consuming and costly. Additionally, minor structural changes, such as altering one carbon in the polymer sidechains or the nature of an aryl group in the repeating unit, can significantly affect their electronic or mechanical properties, positively or negatively. To accelerate and enhance the development of semiconducting materials and to predict their properties before synthesis, computational chemistry serves as a valuable tool. Recent advancements in computing power and algorithm availability have made this increasingly feasible. In this work, we investigate and determine key thermomechanical properties, including glass transition temperatures and persistence lengths, of high-performance donor-acceptor conjugated polymers based on diketopyrrolopyrrole and isoindigo using in silico methods. This study not only provides insights into the molecular mechanisms underlying trends in thermomechanical properties, but also discusses the limitations and advantages of the computational methods. Overall, our work demonstrates that computational methods are an effective and powerful tool for identifying potential design targets and for understanding and rationalizing trends in semiconducting polymers and related emerging electronic devices.
In silico screening of LRRK2 WDR domain inhibitors using deep docking and free energy simulations
Authors: Gutkin Evgeny , Gusev Filipp , Gentile Francesco , Ban Fuqiang , Koby S. Benjamin , Narangoda Chamali , Isayev Olexandr , Cherkasov Artem , Kurnikova Maria G.
Published: December 2023

The Critical Assessment of Computational Hit-Finding Experiments (CACHE) Challenge is focused on identifying small molecule inhibitors of protein targets using computational methods. For the CACHE Challenge #1, the Leucine-Rich Repeat Kinase 2 (LRRK2) WD40 Repeat (WDR) domain was selected as the target for in silico hit-finding and optimization. Mutations in LRRK2 are the most common genetic cause of familial form of Parkinson's disease. The LRRK2 WDR domain is an understudied drug target with no known molecular inhibitors. We developed a framework for the high-throughput structure-based virtual screening of a chemically diverse small molecule space. Hit identification was performed using the large-scale Deep Docking (DD) protocol followed by absolute binding free energy (ABFE) calculations. ABFEs were computed using an automated molecular dynamics (MD)-based thermodynamic integration (TI) approach. 4.1 billion ligands from Enamine REAL were screened with DD followed by ABFEs computed by MD TI for 793 ligands. 76 ligands were prioritized for experimental validation. Our results demonstrate the efficacy of the combined DD and ABFE approaches for hit identification for a target with no previously known hits. This approach is widely applicable for the efficient screening of ultra-large chemical libraries as well as rigorous protein-ligand binding affinity estimation leveraging modern computational resources.
Exploring the Mechanism of the Electrochemical Polymerization of CO2 to hard carbon over CeO2 (110)
Authors: Keller Florian , Döhn Johannes , Gross Axel , Busch Michael
Published: December 2023

Conversion of CO2 to hard carbon is an interesting technology for the removal of carbon dioxide from the atmosphere. Recently, it was shown that CeO2 can selectively catalyse this reaction but we still lack information regarding the reaction mechanism. Using density functional theory (DFT) modelling we explore possible reaction mechanisms that allow for the polymerization of CO2. According to our computations the reaction is initialized by the adsorption of CO2 in an oxygen vacancy. Owing to the rich defect chemistry of ceria a large number of suitable sites are available at the surface. C-C bond formation is achieved through an aldol condensation type mechanism which comprises the electrochemical elimination of water to form a carbene. This carbene then performs a nucleophilic attack on CO2 . The reaction mechanism possesses significant similarities to the corresponding reaction in synthetic organic chemistry. Since the mechanism is completely generic it allows for all relevant steps of the formation of hard carbon like chain growth, chain linkage and the formation of side chains or aromatic rings. Surprisingly, ceria mainly serves as an anchor for CO2 in an oxygen vacancy while all other subsequent reaction steps are almost completely independent from the catalyst. These insights are important for the development of novel catalysts for CO2 reduction and may also lead to new reactions for the electrosynthesis of organic molecules.
Controlling Reactivity and Selectivity in the Mizoroki-Heck Reaction: High Throughput Evaluation of 1,5-Diaza-3,7-diphosphacyclooctane Ligands
Authors: Isbrandt Eric , Chapple Devon , Tu Nguyen Thien Phuc , Dimakos Victoria , Beardall Anne Marie , Boyle Paul , Rowley Christopher , Blacquiere Johanna , Newman Stephen
Published: December 2023

We report a high throughput evaluation of the Mizoroki-Heck reaction of diverse olefin coupling partners. Comparison of different ligands revealed the 1,5-diaza-3,7-diphosphacyclooctane (P2N2) scaffold to be more broadly applicable than common ‘gold standard’ ligands, demonstrating that this family of readily accessible diphosphines have unrecognized potential in organic synthesis. In particular, two structurally related P2N2 ligands were identified to enable the regiodivergent arylation of styrenes. By simply altering the phosphorus substituent from a phenyl to tert-butyl group, both the linear and branched Mizoroki-Heck products can be obtained in high regioisomeric ratios. Experimental and computational mechanistic studies were performed to further probe the origin of selectivity, which suggests that both ligands coordinate to the metal in a similar manner, but that rigid positioning of the phosphorus substituent forces contact with the incoming olefin in a pi-pi interaction (for P-Ph ligands) or with steric clash (for P-tBu ligands), dictating the regiocontrol
Evaluation of Edwuma Pa Fibre Extraction Machine for Sisal and Banana Leaves: A Sustainable Approach for Textile Applications
Authors: Akrofi M. , Pardie S. P. , Ayesu S. M. , Frimpong C.
Published: December 2023

Purpose: This study assesses the effectiveness of a mechanical extraction machine designed for sisal and banana leaves in producing natural fibres.

Design/Methodology/Approach: This study uses experimental research with a mechanical extraction machine to get fibres from banana and sisal leaves. Testing equipment like a scale, microscope, and strength machine is used to analyse the fibres. Flexure analysis is used to optimize the design to achieve a balance between performance, sustainability, and reliability.

Findings: Through analysis of extracted fibres' tensile strength and diameter, as well as extraction efficiency, the study reveals that both banana and sisal leaves hold promise for fibre yield. Banana fibres exhibit a diameter of 0.102mm and tensile strength ranging from 175.71 N/mm² to 423.934 N/mm². In comparison, sisal fibres have a diameter of 0.1mm and tensile strength between 190.96 N/mm² and 1489.50 N/mm².

Research Limitation/Implications: This research underscores the potential for utilizing locally available natural fibres for textiles and industry, exploring the challenges and prospects of mechanical extraction systems for fibre.

Practical Implications: It aligns with the global push for sustainable textiles and offers insights into improving efficiency and viability, essential for integrating natural fibres into the textile sector.

Social Implications: This emphasis on sustainable practices can lead to increased awareness within local communities about the importance of preserving natural resources and ecosystems.

Originality/Value: The flexure analysis conducted in this study unveils the structural resilience of banana and sisal fibres.
Exudative pericarditis with tamponade after COVID-19. Case report
Authors: Dvoretsky Leonid I. , Rachina Svetlana A. , Poltavskaya Maria G. , Andreev Denis A. , Tarykina Elena V. , Plaksina Natalya A. , Minaev Vadim V. , Terekhova Angelina V.
Published: December 2023

A description of a COVID-19 patient with the development of exudative pericarditis complicated by cardiac tamponade is provid. A peculiarity of this case is the presence of an underlying disease in the patient (chronic lymphocytic leukemia), which was in remission for 1.5 years after chemotherapy. Another feature of the patient was the relatively small area of lung damage and the hemorrhagic nature of the pericardial effusion, which persisted for a long time. The insignificant activity of inflammatory markers was noteworthy. Possible mechanisms of development and features of the course of exudative pericarditis in the described patient, issues of diagnosis and treatment of this category of patients are discusse.
Clinical efficiency and safety of riamilovir under various dosage regimens for treatment of acute respiratory viral infections in adults
Authors: Zhdanov Konstantin V. , Maltsev Oleg V. , Kasyanenko Kristina V. , Kozlov Konstantin V. , Sukachev Vitalii S. , Lvov Nikolai I. , Sharabkhanov Valerian V. , Litvinov Alexander A.
Published: December 2023

Aim. To evaluate the clinical efficacy and safety of antiviral drug riamilovir in patients with acute respiratory viral infections (ARVI) of non-coronavirus (SARS-CoV-2) etiology with different dosing regimens.
Materials and methods. The study included 150 patients with ARVI aged 18–27 years (50 patients received riamilovir in the regimen of 250 mg 3 times a day for 5 days, 50 patients received riamilovir in the off label regimen of 250 mg 5 times a day for 5 days, 50 patients received only pathogenetic treatment).
Results. The use of riamilovir in both treatment regimens led to a reduction in the duration of inpatient treatment. The shortest periods of hospitalization were noted in patients who received the study drug at higher daily dosages. The use of riamilovir reduced the duration and severity of general infectious manifestations of the disease, while the shortest total duration of fever and a number of respiratory tract syndromes was registered among people who received riamilovir in the regimen of 1250 mg per day for 5 days, no adverse events were registered, additionally, 100% elimination of ARVI pathogens was noted in 1250 mg per day group.
Conclusion. Riamilovir has shown clinical efficacy and a good safety profile in in both treatment regimens. The dosage regimen of 1250 mg per day led to more significant clinical effects and to 100% elimination of ARVI pathogens in the study group by the 6th day of hospitalization.
Predictors of thromboembolic complications in patients with severe SARS-CoV-2 coronavirus infection
Authors: Podzolkov Valery I. , Volchkova Elena V. , Tarzimanova Aida I. , Bragina Anna E. , Ivannikov Alexander A. , Bykova Ekaterina E. , Shvedov Ilya I. , Oganesyan Karine A. , Isaeva Alena Y.
Published: December 2023

Aim. To identify predictors of the development of thromboembolic complications (TECs) in patients with severe SARS-CoV-2 coronavirus infection.Materials and methods. A single-center observational retrospective study included 1634 patients with a confirmed diagnosis of SARS-CoV-2 coronavirus infection. The patients were divided into 2 groups depending on the availability of the feasibility study. The criterion for inclusion of patients in the main group was the presence of venous feasibility studies in 127 patients (group I), the comparison group consisted of 1507 patients in whom the course of COVID-19 was not complicated by the development of feasibility studies (group II).Results. When performing computed tomography of the chest organs, it was revealed that patients with a feasibility study had a higher percentage of lung tissue damage than patients in the comparison group: 55% [37.5; 67.5] and 37.5% [25.0; 47.5], respectively (p0.001). The average values of C-reactive protein in I patients group were 129 [60.1; 211] ng/l, which was significantly higher than in II patients group – 41.0 [12.2; 97.6] ng/l (p0.001), interleukin-6 – 176 [52.9; 471] pg/ml and 39.4 [11.0; 107] pg/ml (p0.001), respectively. A one-factor regression analysis proved a significant contribution of comorbid pathology to the development of feasibility studies in patients with COVID-19. The presence of three nosologies at the same time: arterial hypertension, coronary heart disease (CHD) and chronic kidney disease increased the probability of a feasibility study by 4.81 times (odds ratio 4.8117, 95% confidence interval 3.2064–7.2207), in patients with arterial hypertension, CHD, chronic kidney disease and type 2 diabetes – by 5.63 times (odds ratio 5.6321, 95% confidence interval 3.1870–9.9531).Conclusion. The presence of severe comorbid pathology significantly increased the risk of developing a feasibility study in patients with COVID-19. The most significant predictors of the development of feasibility studies in patients with severe SARS-CoV-2 coronavirus infection. They are: CHD, arterial hypertension and type 2 diabetes.
The possibilities of impulse oscillometry in the diagnosis of the lung function disorders after COVID-19
Authors: Savushkina Olga I. , Astanin Pavel A. , Nekludova Galina V. , Avdeev Sergey N. , Zaytsev Andrey A.
Published: December 2023

Background. Impulse oscillometry (IOS) is an effort independent method of studying lung mechanics.Aim. To study the diagnostic significance of IOS in assessing lung mechanics after COVID-19.Materials and methods. Spirometry, body plethysmography, diffusion test (DLco), IOS parameters were analyzed in 315 patients (the median age 48 years), the median period from the beginning of COVID-19 to the study was 50 days. Statistical analysis included descriptive statistics, correlation analysis and one-dimensional logistic regression analysis with an assessment of odds ratios.Results. In general group, spirometry and body plethysmography parameters were in normal values, while DLCO was reduced in 61% of patients. Parameters of IOS were analyzed in the general group and between the groups, depending on the value of DLco and total lung capacity (TLC): normal or reduced. In general group, reactance area (AX), hererogeneity of resistance Rrs5–Rrs20, resistance at 5 Hz (Rrs5), reactance at 5 Hz (ΔXrs5) were increased in 29.8%, 17.8%, 6%, 4.8% of patients, respectively, and were statistically significantly higher in the group with reduced TLC, whereas in the group with reduced DLco AX, Rrs5–Rrs20 were statistically significantly higher. Logistic regression analysis showed that patients with Rrs5-Rrs200.07 kPa×sec/l or AX0.32 kPa/l had a 1.99-fold and 2.24-fold increased risk for decrease DLco, respectively, while the risk of decrease in TLC was 2.25-fold (p=0.012) and 3.16-fold (p0.001) higher, respectively.Conclusion. IOS allow to detect both dysfunction of small airways (if AX or Rrs5–Rrs20 are increased) and the risk of restrictive pattern and lung diffusion impairment after COVID-19.
Government, university medicine and epidemics in Siberia (late XIX – early XX century)
Authors: Stepnov Alexei O. , Karpov Rostislav S. , Nekrylov Sergei A.
Published: December 2023

The relationship between government and university medicine in the context of the development of the Asian "colonial" periphery of Russia in the late imperial period are studied. It is concluded that these relationship, the manifestations of which were most pronounced in the period of the fight against epidemics, are not quite standard from the point of view of model of the classical relationship between power and knowledge in the colonial context of European maritime empires. This is connected mainly with the social portrait of the university intelligentsia, with the peculiarities of their professional socialization, which led to the fact that in Siberia they broadcast the experience of the European metropolises, rather than the colonies.
National policy of Ukraine on Rare (Orphan) Diseases
Authors: Iryna Zhyvylo
Published: December 2023

According to the Ministry of Health of Ukraine, 80% of patients with rare diseases in Ukraine die within 5 years due to the lack of systematic diagnosis and qualified treatment. This is more than, for example, 50% in France. As Russia’s military incursion continues to disrupt basic health services, major efforts are needed to restore and strengthen health services, including access to medicines and medical equipment.
Under these circumstances, the heroic work of doctors, both on the territory of our country and abroad, who, despite the challenges faced by the community of rare diseases in Ukraine, did not stop for a moment their work to support and help the community of patients with rare diseases and the mobilization of political advocacy and legislation at the national level.
Currently, humanitarian organizations and the international community are making maximum efforts to generally protect the most vulnerable segment of the population, which is affected by the conflict, cannot leave and does not have access to humanitarian aid. The current situation should not undermine the reality that the needs of people living with a rare disease are real, enormous and unmet.
The creation of legal, economic and administrative mechanisms for the realization of the constitutional rights of the population of Ukraine suffering from rare (orphan) diseases, preservation and strengthening of their health, extension of the period of active longevity and length of their lives is one of the main tasks of the state.
So, the article proposes a structured complex political program document aimed at solving the issues of patients suffering from rare (orphan) diseases. During the development and formation of this state policy, the best practices of developed European countries were used. An overview of the state and problems of national regulatory and organizational support in the field of access to treatment for patients with rare (orphan) diseases was also conducted. Scientific achievements of domestic and foreign researchers, statistical data of state authorities, international organizations and own author’s research were taken into account.
Point Cloud-Based Spatial Environment Development for Near Real-Time Erection Simulation in Shipyards
Authors: Kim Yeon-Jun , Wang SeungYeol , Jang Jaewon , Park Bon-Yeong , Lee Dong-Kun , Oh Daekyun
Published: December 2023

Interference and collisions often occur in the loading process at shipyards. Existing simulation methods focus primarily on resource processes and schedules, and there is a lack of real-time reflection in the complex and highly variable loading process. This study aims to develop a spatial environment incorporating real-time product data, such as hulls, and confirms its effectiveness by simulating various construction scenarios. As a method, a near real-time spatial environment based on broadband laser scanning was established, with the situation of loading heavy cargo assumed when converting an existing ship into an LNG dual-fuel propulsion ship. A case study simulation of near-real-time cargo loading processes was then conducted using Unity 3D to confirm the interference and collision risks within the spatial environment. The results indicated that interference occurred in structures previously not identified in the design data, and a collision occurred during the loading object erection phase. The simulation confirmed that the identification of interference and collision risks during the erection phase highlights the need for a relocation or removal process of potential hazards before erection takes place. An improved erection simulation that integrates near real-time data could effectively prevent interference and collision risks.
Marías. Entre la adoración y el estigma
Authors: Montesinos Castañeda María
Published: December 2023

Marías. Entre la adoración y el estigma originated in the seminar “Between adoration and stigma: mothers, virgins, and prostitutes.” This event was an extra activity of the course “Analysis and interpretation of the image,” taught in the Art History and History Bachelors at the Universitat de València. In addition, the writers of this book are members of the research roup “Apes. Estudis de Cultura Visual de la Universitat de València,” which included this seminar as a part of their Educational Innovation Project (2019-2020).
Entrevista a Paula Ortiz
Authors: Aparicio Vinacua Beatriz
Published: December 2023

Paula Ortiz Álvarez, cineasta española y aragonesa, es directora, guionista, productora e integrante de CIMA, la Asociación de mujeres cineastas y de medios audiovisuales de España. Desde los inicios de su carrera ha trabajado formatos como el cortometraje, el largometraje, la serie de televisión, la publicidad y el vídeo musical. Todo ello sin dejar de lado el mundo académico, como autora y docente, dado que es profesora en el grado de Comunicación Audiovisual de la Universidad de Barcelona.
Crossing the Mirror: an Approach to the Social Perception of the Prehistoric Past from a Gender Perspective
Authors: Mouriño Andrea , Comendador Beatriz
Published: December 2023

Los medios de comunicación son un sistema de comunicación inmediata y efectiva, que forman una cultura de masas constituida por símbolos, mitos y estereotipos de los individuos como una forma de «producción industrializada de la realidad». Dentro del marco conceptual de la Arqueología Pública, desde una perspectiva crítica y feminista, se presenta un ensayo de aproximación a la percepción social del pasado prehistórico en el ámbito de la Cultura Popular contemporánea. El propósito de este trabajo es analizar y conceptualizar los mensajes e ideas generados por la cultura de masas alrededor de la representación de la humanidad prehistórica para entender cómo se construyen y qué tipo de sociedad promueven. Para ello, se aborda la imagen de la cavewoman desde su configuración en el imaginario popular para analizar los estereotipos y sexismos instalados, su origen, su repercusión en la percepción social de la Prehistoria y qué papel juega esta idea en la sociedad contemporánea, y más particularmente, qué implicaciones tienen para las mujeres. Debemos, atravesar este espejo distorsionado e imagen del pasado, creada por la sociedad de consumo proyectando la suya propia, donde la imagen de la mujer no es sólo la del pasado, sino también la del futuro.
Las cajas negras de la posmemoria
Authors: Bettaglio Marina
Published: December 2023

Resumen: La recuperación de la memoria histórica de la Guerra Civil y del franquismo plasmada a través del Noveno Arte con frecuencia refleja una interpretación androcéntrica del concepto de “postmemoria” (Hirsch), que se declina sobre todo a partir de una genealogía patrilineal. Centrando la atención en la recuperación de una perspectiva matrilineal en cuanto a la memorialización del conflicto bélico y la posguerra, el presente artículo propone analizar las que denomino «cajas negras» (Latour) de la postmemoria, es decir aquellos cuerpos casi inermes que dan fe de unas maternidades traumáticas como ocurre en la protagonista de El ala rota de Antonio Altarriba y Kim. A partir del análisis de las metáforas visuales empleadas en estas narrativas gráficas y en diálogo con las teorizaciones de Bruno Latour y de Jane Bennett en cuanto a la materialidad de los cuerpos y Adriana Cavarero por lo que se refiere a la escritura de las historias de vida, se analiza la centralidad del cuerpo en un tipo de reelaboración artística mediada por la interlocución.

Abstract: In graphic narratives, the process of recovering the historical memory of the Civil War and of Francoism often reflects an androcentric interpretation of the concept of “postmemory” (Hirsch), that is, an interpretation shaped especially by a patrilineal genealogy. The current article instead shifts the critical focus to a matrilineal perspective by proposing ananalysis of what I call the «black boxes» (Latour) of postmemory, the almost inert bodies that bear the memory of traumatic motherhood, specifically the protagonist of El ala rota by Antonio Altarriba and Kim. Through an analysis of visual metaphors, and in dialogue with Bruno Latour's and Jane Bennett's theories of the materiality of bodies as well as Adriana Cavarero's theory of life writing, I examine the importance of the body in a kind of artistic elaboration mediated through interlocution.
Refugiados: desde los cómics de la memoria a los cómics de denuncia (en torno a Asylum de Javier de Isusi)
Authors: Touton Isabelle
Published: December 2023

Resumen: Después de una reflexión inicial sobre las huellas gráficas (fotográficas y dibujadas) del exilio español de los perdedores de la guerra a finales de los años 30, en particular en el momento de la Retirada y de los campos de concentración en el sur de Francia, se propone un análisis de la novela gráfica Asylum de Javier de Isusi como trenzado de historias de vida de refugiados españoles del pasado, procedentes de Euskadi, y de refugiados de hoy en el País Vasco. Se muestra cómo la obra se inscribe en un recurso comparatista didáctico entre pasado y presente que utilizan tanto ciertas ONG como algunos periodistas y artistas militantes.

Résumé : Après une réflexion initiale sur les traces graphiques (photographiques et dessinées) de l’exil espagnol des perdants de la guerre dans la deuxième moitié des années 30, en particulier lors de la Retirada et l’enfermement dans les camps de concentration du sud de la France, nous proposons une analyse du roman graphique Asylum de Javier de Isusi comme résultat du tressage d’histoires de vie de réfugiés espagnols basques du passé et de réfugiés d’aujourd’hui au Pays Basque. Il sera aussi montré comment cette oeuvre s’inscrit dans un recours comparatiste didactique entre le passé et le présent qu’utilisent tout autant certaines ONG que des journalistes et artistes militants.
Campos de lectura expandida
Authors: Vilches Gerardo
Published: December 2023

Reseña de: DEL REY CABERO, E., (Des)montando el libro. Del cómic multilineal al cómic objeto, León, Universidad de León, 2021.
English teaching method training to improve the competency of kindergarten teachers
Authors: Maharddhika Rizkiana , Prasetianto Mushoffan , Ruminar Hafida , Prasetyaningrum Dian Islami
Published: December 2023

The English Teaching Methods training program as a Community Service activity was carried out at one of the kindergarten schools, in Malang city. This training aims to improve the professionalism of kindergarten Teachers in teaching English materials. This activity consists of several stages namely preliminary study, material preparation, onsite training, and evaluation. The preliminary study, which involved discussion with presenters and school principals, was conducted to identify problems and assess teachers' needs. During the training process, teachers are equipped with theoretical frameworks, methodological examples, and English teaching materials specifically tailored for the effective instruction of young learners. Subsequently, the educators were allocated a period for discussion, during which they engaged in the development of inventive approaches and media. These outputs were subsequently delivered on the next day. The training instructors also offered feedback for every new method and media creation that was presented by the teachers. Upon the end of the training program, the participants offered testimonials and suggested ideas pertaining to the training. In addition, the lecturers offered instructional objects that can be utilized when teaching English in kindergarten.
Increasing the productivity of MSMEs processing herbal medicine with appropriate technology for choppers and grinders
Authors: Susanto Riswan Eko Wahyu , Bahtiar Ahmad Dony Mutiara , Bakhtiar Yohan , Huda Miftakhul , Rojikin Setiyo
Published: December 2023

Indonesian society has traditional healing methods that involve a variety of uses of plants, animal products, and minerals. Medicinal plants have been used and mixed well by various ethnic groups of Indonesian society as herbal medicine. Wahyu Alam Foundation MSMEs located in the city of Kediri, are farmers and herbal plant entrepreneurs who have problems. The Wahyu Alam Foundation MSME as a community service partner has problems related to processing herbal plants with the process still being manual, so they need help to make the production process easier. The results of this service activity include a visible increase in productivity, previously Manual production in two stages after direct chopping, and grinding, took 20 minutes per kg and 20 kg of product was obtained in a day, resulting in a faster time of 10 minutes per kg, while the product yield increased to 40 kg per day. Based on data obtained by MSMEs Herbal Medicine, the predicted increase in profits was at an average of 18%, while the average increase in rupiah was 3.222 million. This increase was due to the optimal use of machines, along with increased marketing due to the increasing demand for herbal medicine on the market.
Utilizing immunostimulants and probiotics for enhancing vannamei shrimp (Litopenaeus vannamei) aquaculture activities
Authors: Samara Syifania Hanifah , Mahasri Gunanti , Kusdarwati Rahayu , Chaerunissa Dheani Nur Ahadya Syifa , Nikmah Anggun Khoirun , Indarmastuti Elisabeth Benita
Published: December 2023

Vannamei shrimp is one of the important fisheries commodities in Indonesia. This is because vannamei shrimp are expensive, popularly consumed by people around the world, and can be cultured. However, vannamei aquaculture activities are still hampered by disease, less production, and lack of technology implementation. Kedung Pandan Village (Jabon, Sidoarjo, East Java) is one of the potential areas for v vannamei shrimp aquaculture which is also constrained by this issues, so many farmers have gone out of business. This community service activity aims to increase the productivity of vannamei shrimp cultivation by administering immunostimulants and probiotics. In its implementation, this community service activity collaborates with "Putri Mandiri", a group of vaname shrimp farmers in Kedung Pandan Village. This activity is carried out in the stages of preparation, implementation of activities (socialization-demonstration), and evaluation.  Socialization and demonstration activities were carried out on August 9 2023 and were enthusiastically participated by residents. The results of this activity indicate that the knowledge of farmers in Kedung Pandan Village, Jabon, Sidoarjo has increased and can use immunostimulants and probiotics in vannamei shrimp farming activities.
Integrated Late Santonian-Early Campanian sequence stratigraphy, New Jersey Coastal Plain: Implications for global sea-level studies
Authors: Mizintseva Svetlana , Browning James V. , Miller Kenneth G. , Olsson Richard K. , Wright James D.
Published: December 2023

Recent studies of the Santonian-lower Campanian section (Merchantville Formation) in two coreholes (Ancora and Bass River) from the New Jersey coastal plain postulated the existence of concatenated sequences in glauconitic facies (Miller et al. 2004). The lithologic expression of unconformities within the Merchantville glauconitic sediments is obscure and their resolution requires an integrated stratigraphic approach. Here, we present detailed litho-and biostratigraphic analyses of the Merchantville Formation sequences in four New Jersey coastal plain coreholes (Sea Girt, Ancora, Millville, and Bass River). Biofacies analysis reveals four benthic foraminiferal assemblages from inner to middle neritic environments. Correlation of benthic foraminiferal biofacies, percentage of planktonic foraminifera, and lithologic data indicates that paleowater depths varied between 30 and 75m. The correlation of biostratigraphy, benthic foraminiferal biofacies, lithology, and gamma logs delineates unconformities, and identifies three sequences within the Merchantville Formation (MeI, MeII, MeIII). The ages of these sequences have been constrained by calcareous nannoplankton biostratigraphy (MeI: CC16; MeII: CC17-18; MeIII: CC18-19) from 78.8 to 84.5 Ma. The Merchantville I sequence is observed in the Sea Girt and Bass River coreholes. The Merchantville II and III sequences are present throughout the New Jersey coastal plain, and the ages of the Merchantville II and III sequences boundaries are similar to those of North Carolina, and North-Western Europe suggesting an interregional cause of sequences boundaries. Comparison of the New Jersey shallow marine sequences with the deep-sea record from DSDP Site 511 (Falkland Plateau) show that the episodes of sea-level fall in New Jersey are synchronous with 18O increases. Our data imply that the Merchantville sequence boundaries may be attributed to ice volume increases and support the contention that global sea-level changes were controlled by ice-volume variations even during the peak warmth of the Cretaceous.
GOAL PROGRAMMING APPROACH FOR SERVICE STAFF SCHEDULING PROBLEM IN A RESTAURANT
Authors: İNAN Hüseyin Ertan
Published: December 2023

Personnel scheduling plays a crucial role in the service industry, particularly in labor-intensive businesses like restaurants. The effective allocation of shifts for employees is essential to ensure uninterrupted service and optimize profitability. Poor scheduling can negatively impact both the business and its employees, resulting in decreased profitability and increased physical and mental strain. Continuity of service is essential in restaurant businesses. Shift plans ensure that the service continues uninterrupted by assigning personnel to various shifts. In order to provide the best service in restaurants, the daily shifts of the personnel working in shifts should be planned systematically. In this study, it is aimed to create the shift schedules of the service personnel in the Eskişehir branch of one of the leading restaurants in Turkey. The restaurant employs two types of service personnel: bussers and waiters. The number of required personnel varies across different days and shift periods. In this context, personnel shift schedules were created by using the goal programming method in the study, taking into account the business objectives, personnel needs and shift characteristics. The results of this study can contribute to the literature on staff scheduling in restaurants and can help restaurant businesses create more effective schedules.
The Effect of SiC and MgO Ceramic Reinforcements on the Mechanical Behavior and Electrical Properties of the Composite Structure in Al7075/SiC/MgO Hybrid Composites
Authors: ERTEN Mustafa Yasin , YİLMAZEL Rustem , FİLAZİ Ahmet , PUL Muharrem
Published: December 2023

In this study, certain technical properties of new generation aluminum-based composites, obtained by combining the Al7075 alloy widely used in the industrial field with two different ceramics, were investigated. For this purpose, SiC and MgO ceramics in particle form were reinforced into the Al7075 matrix material using powder metallurgy technique and composite structures were produced in three different reinforcement ratios. Measurements to determine electrical resistance and conductivity and bending and compression strength tests were performed on the obtained composite structures. The density and porosity amounts of the composite structures were also determined, and their microstructures were examined with a digital microscope. With the increase of SiC/MgO amount in the aluminum composite structure, the electrical resistance increased, and the conductivity value decreased. With the effect of SiC/MgO reinforcing materials, the density value of the composite structures decreased while the amount of porosity increased. The hardness values increased due to the effect of SiC and MgO ceramics in the structure. The bending and compression strength values initially increased and then started to decrease with the increase of reinforcement ratios. It has been determined that the formation of porosity in the composite structure negatively affects the mechanical behavior. The second important factor was evaluated to be the amount and shape of ceramic-based reinforcement particles in the structure. Due to the effect of SiC, which has very high electrical resistance, and MgO, which has dielectric properties, the electrical conductivity values of the composite structures decreased. The increase in electrical resistance and the decrease in electrical conductivity were directly proportional to the amount of ceramic-based reinforcement particles in the composite structure.
Farklı Beton ve Çelik Sınıfı Kullanımının Yapıların Zaman Tanım Alanında Analiz Sonuçlarına Etkilerinin İncelenmesi (Ocak 2020 Elazığ Depremi Örneği)
Authors: YENİÇELİK Nazan , ER Şule , AVANOĞLU SICACIK Eda
Published: December 2023

Ülkemiz aktif fayların bulunduğu bir deprem ülkesidir. Deprem bir doğa olayıdır ancak depremden kaynaklanan yapısal hasarları azaltmak veya ortadan kaldırmak mümkündür. Ülkemizde ağır maddi manevi kayıpların yaşandığı depremler olmuştur. Acı tecrübeler neticesinde yapısal anlamda pek çok iyileşme olmasına rağmen projelendirme, uygulama noktalarında hala eksiklikler mevcuttur. Elazığ Sivrice’de 24 Ocak 2020’de 6.8 aletsel büyüklüklü bir deprem yaşanmıştır. Sığ bir deprem olması nedeniyle etkisi hissedilmiştir. Deprem sonrası yapılar incelendiğinde beton dayanımlarının düşük olduğu, sargılama donatılarının yetersizliği, düz donatı kullanımı ve yetersiz bindirme boyu dikkat çekicidir. Binalar arasında yeterli miktarda derz bırakılmamış ve giriş katlarda yeterince dolgu duvar olmaması nedeniyle yumuşak katlar oluşmuştur.

Bu çalışmada betonarme çerçeve sistemli bir bina modeli incelenmiş, farklı beton dayanımı ve donatı sınıfları ile 2018 Türkiye Bina Deprem Yönetmeliği kullanılarak analizler yapılmıştır. SAP 2000 sonlu elemanlar programı yardımıyla Zaman Tanım Alanında analizler gerçekleştirilmiştir. Seçilen ana parametreler; beton sınıfı ve donatı sınıfıdır (Beton sınıfları: C12, C20 C25 ve C30; donatı sınıfları: S220 ve S420). Taban kesme kuvvetleri, tepe noktası yer değiştirmeleri elde edilmiş ve karşılaştırılmıştır.