bluuebunny/crossref_metadata_2025 huggingface dataset:
A FORMAÇÃO VIRTUOSA NA ESCOLA
Authors: Andrade Regiani Ferreira Martins Giórgia , Bezerra de Carvalho Alonso
Published: March 2019

The reflection on the field of Ethics has always permeated philosophical reflection. Ethics can not
be dissociated from citizen formation and the formation of the critical subject in relation to the
world and social relations. The objective of this dissertation is to draw a dialogue with the Ethics,
from authors like Kant and Aristotle. It discusses through the theoretical framework the conditions
and processes in which the virtuous formation of man is given. It brings some reflections on the
contemporary school. This issue is indissociable from a pedagogical training geared towards
human, critical and citizen formation. The exchanges, experiential and world views constitute a
complex web of meanings for a rich reflexive, ethical and philosophical formation to the student.
In this sense, the school has the potential to be explored, even though it is still incipient, since its
formation and learning processes that lead to autonomy and ample virtuous and ethical
formation, to think and read the world critically have not been unleashed.
A IMPLANTAÇÃO DE PROGRAMAS E AÇÕES INCLUSIVAS EM UM MUNICÍPIO DO
OESTE PAULISTA: PDDE ACESSIBILIDADE
Authors: Mayra Samuel da Silva Ana , Tomoe Moriya Schlünzen Elisa , Aparecida do Nascimento dos Santos Danielle , Virginia Isiano Lima Ana
Published: March 2019

In order for all to be included according to their needs and specificities, the objectives proposed by
school education must be directed to the recognition and problematization of differences. The
objective of this study was to analyze the implementation of programs and actions proposed in
the scope of the National Policy of Special Education from the perspective of Inclusive Education
(BRASIL, 2008), in a school located in a small municipality in the west of São Paulo. The
methodology consisted of formative intervention on public educational policies, programs and
actions in an inclusive perspective, and participant observation to follow the actions developed by
the school management team, based on a qualitative approach. The programs and actions of the
Ministry of Education are effective, since they aim to contribute and help with the guarantee, not
only of access, but also of the permanence with the quality of students in the school context.
Impactos dos parâmetros em Modelos de Interação Espacial: uma discussão metodológica / Impacts of parameters in Spatial Interaction Models: a methodological discussion
Authors: Carvalho Paulo Fernando Braga , Laudares Sandro , Alves Diego Filipe Cordeiro , Faria Erick De Oliveira
Published: March 2019

Interessantes aplicações dos dados espaciais são vistas em estudos de interação espacial que usam modelos matemáticos adaptados de outras ciências ou criados para contextos específicos e, em geral, os principais elementos nas expressões algébricas que representam esses modelos são: as distâncias entre as Unidades Espaciais Básicas (UEB) e a magnitude (massa) de cada UEB. O problema discutido neste trabalho é: ao usar diferentes atributos ou medidores de distância os resultados obtidos com a aplicação de modelos matemáticos de interação espacial podem provocar conclusões distintas? Neste estudo foi aplicado o Modelo Potencial para cálculo e avaliação do potencial de atração dos municípios da Mesorregião do Triângulo Mineiro/Alto Paranaíba. Os resultados deste trabalho mostram que a escolha de variáveis e a forma de medir distância provocam resultados com diferenças significativas dentro de um mesmo modelo matemático que lida com a interação espacial.Palavras–chave: Interação Espacial, Modelos, Métodos QuantitativosAbstract Interesting spatial data applications are seen in spatial interaction studies using mathematical models adapted from other sciences or created for specific contexts, and in general the main elements in the algebraic expressions representing these models are: the distances between the Basic Space Units (BSU) and the magnitude (mass) of each (BSU). The problem discussed in this work is: when using different attributes or distance metrics can the results obtained with the application of mathematical models of spatial interaction lead to different conclusions? In this study the Potential Model was applied to calculate and evaluate the attraction potential of the municipalities of the Triângulo Mineiro / Alto Paranaíba Meso-region. The results of this work shows that the choice of variables and the way of measuring distance causes results with significant differences within a same mathematical model that deals with the spatial interaction.Keywords: Spatial Interaction, Models, Quantitative Methods
Análise Temporal do Uso e Cobertura da Terra na Bacia do Rio Boa Vista, Ouro Preto do Oeste-RO / Temporary Analysis of Land Use and Coverage in the Rio Boa Vista River, Ouro Preto do Oeste-RO
Authors: Andrade Leonardo Rosa , Moreira João Paulo Papaleo Costa , Santos Alex Mota dos
Published: March 2019

O município de Ouro Preto do Oeste tem na microbacia do Rio Boa Vista a principal fonte de água para abastecimento público, e vem enfrentando problemas de baixa disponibilidade hídrica durante o período de estiagem. No sentido de compreender melhor a microbacia e de que maneira ocorreu a dinâmica de uso e ocupação da terra na mesma, este estudo realiza uma análise temporal de imagens de satélite para os anos de 1973, 1984, 1993, 2007 e 2018, relacionando às mudanças da paisagem com as características da microbacia e o tipo de atividade econômica, além de propor medidas de gestão dos recursos hídricos que possam melhorar a qualidade e aumentar a disponibilidade hídrica na microbacia. Nos períodos analisados houve um aumento progressivo das áreas antropizadas, passando de 52,59 km² (29,03%) em 1973, para 155,47 km² (85,94%) em 2018. A análise temporal da cobertura vegetal da microbacia do Rio Boa Vista indica um comportamento coerente com o processo vigente nas últimas décadas na região, ou seja, antropização inicial acelerada, com posterior remoção gradual da floresta. Assim, foi possível identificar que os fragmentos de floresta remanescentes estão isolados e que nas porções oeste e sul da microbacia encontram-se as áreas mais vulneráveis as ações de erosão, dado o relevo, o tipo de solo, o elevado índice de antropização e a criação de gado.Palavras–chave: Ocupação da Amazônia, Sensoriamento Remoto, Gestão de Recursos Hídricos.Abstract The county of Ouro Preto do Oeste have the Boa Vista River the primary source of water for public supply and has been facing problems of low water availability during the dry season. In order to better understand the watershed and how the dynamics of use and occupation of the land as well, this study performs a temporal analysis of satellite images since 1973, 1984, 1993, 2007 and 2018, relating to changes of the landscape with the characteristics of the watershed and the type of economic activity, in addition to propose measures of water resources management that can improve the quality and increase the availability of water in the watershed. In the analysed period there was a progressive increase in the areas occupied by man, from 52.59 km² (29.03%) in 1973, to 155.47 km² (85.94%) in 2018. The temporal analysis of the vegetation cover of the watershed of the river Boa Vista indicates a behaviour consistent with the current process in recent decades in the region, i.e. anthropisation accelerated initial, with gradual subsequent removal of the forest. Thus, it was possible to identify that the remaining forest fragments are isolated and that in the West and South portions of the watershed are the most vulnerable areas erosion actions, given the topography, soil type, the high level of anthropisation and cattle breeding.Keywords: Occupation of the Amazon, Remote Sensing, Water Resources Management.
Giuseppe Antonio Landi: das táticas aventurosas na Amazônia Pombalina à renovação do barroco na Santa Maria de Belém do Grão-Pará
Authors: Silveira Flávio Leonel Abreu da
Published: March 2019

O artigo em questão busca refletir sobre a importância de Giuseppe Antonio Landi (1713-1791) para reconfiguração das feições da cidade de Santa Maria de Belém do Grão-Pará, no século XVIII, no contexto da Amazônia Pombalina. Trata-se de uma reflexão a partir do campo da Antropologia Urbana que considera as transformações das paisagens citadinas mediante as agências do ilustrado bolonhês, que mesclam projetos pessoais a projetos expansionistas na América portuguesa.
Use of Nail Dermoscopy in the Management of Melanonychia
Authors: Starace Michela , Alessandrini Aurora , Brandi Nicolò , Piraccini Bianca Maria
Published: March 2019

The term melanonychia describes a black-brown-gray pigmentation of the nail plate that, in most cases, appears as a longitudinal band. Melanonychia can be observed at any age, affecting one digit or several digits, in both fingernails and toenails. Its causes can be difficult to differentiate clinically and depend on the number of bands and on their color, edge, and width. For this reason, especially in adults and when the pigmentation is localized in one single digit, biopsy and histopathological examination still represent the gold standard for a definitive diagnosis. Dermoscopy should be used routinely in the evaluation of a pigmented nail, as it provides important information for the management of melanonychia and can help avoid unnecessary nail biopsies. In cases of melanonychia it is important to establish whether the pigment is melanin or not and to determine whether the pigmentation of melanin is due to activation or proliferation and whether it is benign or malignant.
Dermoscopic Features of Psoriasis, Lichen Planus, and Pityriasis Rosea in Patients with Skin Type IV and Darker Attending the Regional Dermatology Training Centre in Northern Tanzania
Authors: Nwako-Mohamadi Maitseo K. , Masenga John E. , Mavura David , Jahanpour Ola F. , Mbwilo Eva , Blum Andreas
Published: March 2019

Background: Papulosquamous skin diseases can be challenging to diagnose, especially in dark skin. Dermoscopy is reported to be helpful, but few data are available on its use in skin type IV or darker.Objective: To describe dermoscopic features in plaque-type psoriasis (PP), lichen planus (LP), and pityriasis rosea (PR) patients attending the Regional Dermatology Training Centre in Moshi, Northern Tanzania, and to compare findings with published data.Methods: A descriptive cross-sectional study was conducted at a tertiary hospital from October 2016 to June 2017. Fifty-six patients with PP, 25 with LP, and 9 with PR were enrolled consecutively. Clinical diagnosis was confirmed with histopathology in 74.4%. Dermoscopic vascular and nonvascular features from 225 lesions were analyzed.Results: Of the 90 patients enrolled, 58.9% were male and the median age was 50 (interquartile range 32.8-60.0) years. In PP lesions, red dots were found in 64.2% and white scale in 45.5%. In LP lesions the background was violet in 45.5% and 58.2% revealed Wickham striae. In PR lesions a dull red background was found in 50.0%, white scale in 83.3%, but no vessels were detectable.Conclusion: Dermoscopy features in PP, LP, and PR in dark skin are mostly similar to those in light skin.
BRAF Mutation Status in Primary, Recurrent, and Metastatic Malignant Melanoma and Its Relation to Histopathological Parameters
Authors: Spathis Aris , Katoulis Alexander C , Damaskou Vasileia , Liakou Aikaterini I. , Kottaridi Christine , Leventakou Danai , Sgouros Dimitrios , Mamantopoulos Andreas , Rigopoulos Dimitrios , Karakitsos Petros , Panayiotides Ioannis G.
Published: March 2019

Background: BRAF mutations are a common finding in malignant melanoma (MM). Nevertheless, apart from their significance as a therapeutic target in advanced melanoma, their prognostic value is still debated.Objective: To assess BRAF mutation status in primary, recurrent, or metastatic MM and its correlations with histopathological findings.Methods: We analyzed 203 samples from 178 consecutive patients: 129 primary cutaneous MM, 49 metastatic and recurrent MM of unknown primary site, and 25 cases of recurrences or metastases of primary MM. BRAF mutations in exon 15 were identified with real-time polymerase chain reaction and/or direct sequencing or pyrosequencing. Histopathological examination was performed according to standard procedures.Results: We observed a 42.1% prevalence of BRAF mutations at codon 600 among our patients, 84% of whom harbored the V600E mutation. Mutations showed a statistically significant increase in younger patients (P = 0.011), in ulcerated tumors (P = 0.020), and in tumors lacking solar elastosis in adjacent dermis (P = 0.008). Mutations were also more common in male patients, as well as in primary MMs of the torso, and in nonvisceral metastases, however without reaching statistical significance. Logistic regression analysis identified type and ulceration as the only significant predictors of BRAF mutation. The highest frequencies of mutated BRAF were identified in superficial spreading and nodular types, and the lowest in acral lentiginous and lentigo maligna types. In situ MM and primary dermal melanoma displayed intermediate frequencies.Conclusion: Frequency of mutated BRAF is type-related and correlated with ulceration, a known adverse prognostic factor.
Educação permanente e humanização na transformação das práticas na atenção básica
Authors: Lopes Maria Tereza Soares Rezende , Labegalini Célia Maria Gomes , Silva Maria Elisabeth Kleba da , Baldissera Vanessa Denardi Antoniassi
Published: March 2019

The objective was to evaluate the processes of organization and implementation ofhumanization according to the National Policy of Continuing Education in PrimaryHealth Care. Qualitative research was carried out in an evaluative perspectiveanchored in the National Policy of Continuing Education in Health developed with53 workers from primary health care units of a municipality in the state of Paraná.Data were collected through focal groups and transcribed verbatim. The resultswere presented in three evaluative matrices that evidenced the implantation andorganization of humanization conducted by continuing health education practices,emphasizing management, collective practices, and the academy as drivers of thisprocess. The Policies of Continuing Education and Humanization have positivelyinfluenced the work processes of health teams in primary care, in the sense oftransforming practices and knowledge.
Arte Hispano-Musulmán del siglo X : el arte califal
Authors: Aguilar García Dolores
Published: March 2019

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Reseñas Bibliográficas
Authors: Gutiérrez Rizo Teresa , Benarroch Benarroch Alicia
Published: March 2019

RESEÑA de : Fernández Ballesteros, R y Carrobles J.A.I. Evaluación conductual o metodología y aplicaciones. Ed. Pirámides, 1981. RESEÑA de : Einstein, Albert y Infeld, Leopold. La física, aventura del pensamiento. Buenos Aires : Ed. Losada, 1939.
Cultura y Sociedad: el ejemplo de Kabilia
Authors: Yacine Tassadit
Published: March 2019

El surgimiento de una definitiva reivindicación cultural beréber a partir de la década de los ochenta, tiene un exponente esencial en la región argelina de Kabilia. Los movimientos propiciados por los intelectuales (Mouloud Mammeri puede ser considerado como la personificación de esta corriente) y los sectores populares, ayudan a definir la bereberidad en su carácter genérico aglutinador de todos los pueblos de lengua y cultura bereberes. Frente a esto, la barrera -¿infranqueable?- de las instituciones gubernamentales con instrumentos culturales mediatizadores vehiculadlos por lenguas, bien de prestigio religioso -como el árabe-, bien de prestigio colonial -como el francés- intentando la represión de las reivindicaciones culturales, y políticas, de una cultura ignorada y combatida durante siglos.
Datos de gramática contrastiva rifeña-española
Authors: Moufra Naima
Published: March 2019

Aunque de forma parca, la literatura colonial española presenta algunos estudios filológicos de envergadura. Así, sirve de base a este estudio de gramática comparativa, la obra de P. Sarronaindía "Gramática de la lengua rifeña", editada en Tánger, en 1905, que junto a otros trabajos, como los de Ginés Peregrín, Esteban Ibáñez, etc., se constituyen en los exponentes referenciales de las visiones culturales e ideológicas de determinados grupos sociales (misioneros, militares, comerciantes, etc.) respecto al enfoque de la implantación del Protectorado español en Marruecos.
Una orientación propedéutica al másigt hablado en Melilla
Authors: Valverde Martín José Antonio , Kaddur Mohamed Halifa , Maanan Yamila Mohamed
Published: March 2019

Este artículo recoge uno de los muchos esquemas posibles para la iniciación en el conocimiento del másigt hablado en Melilla, un idioma que constituye una de las entidades culturales fundamentales de nuestra ciudad. Este esquema adopta un objetivo meramente propedéutico en dos sentidos: a) su ciclicidad, esto es, partiendo de unos presupuestos gramaticales y de un vocabulario mínimo se sientan unas bases (lo más adaptadas posibles al español en cuanto a escritura) para ampliarse cuantitativamente y cualitativamente; b) su orientación fundamental que alude a la ciclicidad pretendida en función de la oralidad y la reflexión a realizar por el lector.
Tradición, continuidad y modernidad en el derecho consuetudinario islámico: ejemplos del Marruecos beréber y de las agencias tribales pujtunes de Pakistán
Authors: Hart David M.
Published: March 2019

El derecho consuetudinario beréber, nucleado en torno a un corpus de tradición oral, tiene, sin embargo, importantes manifestaciones escritas —en lengua árabe— en al menos tres sociedades bereberófonas —los rífenos del Norte de Marruecos, los ishilhayen o swasa del Alto Atlas occidental/Sus/Anti-Atlas, y, los kabylios de Argelia— caracterizadas por una base social de agricultores sedentarios. Estos auténticos archivos locales custodian los documentos llamados qanun-es, testimonios de las vicisitudes de las interrelaciones sociales en todos los ámbitos. En el marco de los impactos desde los puntos de vista de la tradición, la continuidad y la modernidad, la visión de la antropología social, testimoniada por los trabajos de campo, realza papel jugado desde la época precolonial por los vínculos generados por el derecho consuetudinario, ahora considerado en un cuadro comparativo que engloba a las relaciones jurídicas en el antiguo espacio de las agencias tribales de la frontera Noroeste de la India Británica, el actual estado de Pakistán.
Cisneros y el Norte de África
Authors: Avilés Fernández Miguel
Published: March 2019

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Notas sobre la Cartofilia melillense : Diego Mullor, caricaturista
Authors: Díez Sánchez Juan
Published: March 2019

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La Junta Local de Deslindes y Amojonamientos de Melilla (1866-1900)
Authors: Domínguez Llosá Santiago , Rivas Ahuir Mª de los Ángeles
Published: March 2019

El objeto de la presente comunicación es el estudio de la actuación de la Junta Local de Deslindes y Amojonamientos de Melilla, organismo creado en la segunda mitad del siglo pasado, y cuya principal misión era aclarar la caótica situación en la que se encontraban tanto las propiedades públicas como las particulares.
La imagen norteafrícana según el Archivo Municipal de Málaga (Originales y Provisiones de los Reyes Católicos y Carlos I)
Authors: Vera Delgado Ana Mª
Published: March 2019

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Cultura y vida : la poesía de Miguel Fernández
Authors: Miró Emilio
Published: March 2019

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Retórica de la ceguera: una poética para Miguel Fernández
Authors: Teruel José
Published: March 2019

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Fondos documentales para el estudio de la presencia española en el continente africano conservados en el Archivo General de la Administración
Authors: Valverde Zabaleta María del Carmen
Published: March 2019

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Proyección de España en África : la documentación de la Sección de Estado del Archivo Histórico Nacional
Authors: Castro Martos María Pilar
Published: March 2019

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Los archivos de Melilla la Vieja y su dispersión documental
Authors: Mir Berlanga Francisco
Published: March 2019

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Problemática cuestión de las posesiones españolas en la Argelia del siglo XVIII : caso de Orán y Mazalquivir
Authors: Terki-Hassaine Ismet
Published: March 2019

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La música militar en tiempos del general San Martín
Authors: Roales-Nieto y Azañón Amalia
Published: March 2019

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The impact of emigrant remittances on Spanish and Scottish society in the second half of the twentieth century
Authors: Brock Jeanette M.
Published: March 2019

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El viaje a Italia en las obras de Cervantes: ¿ficción o autobiografía?
Authors: Monga Luigi
Published: March 2019

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La evolución del castellano en los Estados Unidos
Authors: González Alfredo
Published: March 2019

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Caminando en la didáctica de la lengua rifeña
Authors: Hassan Yahia Jahfar
Published: March 2019

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Atención educativa a las necesidades especiales relacionadas con el contexto sociocultural. Medidas administrativas para la atención de los alumnos con necesidades de compensación educativa
Authors: Cano Moreno Jorge
Published: March 2019

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Introducción : "Aldaba" versus Melilla, 1984
Authors: Moga Romero Vicente
Published: March 2019

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La numismática y Melilla
Authors: Barrio Fernández de Luca Claudio
Published: March 2019

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El paisaje, la guerra y el nacionalismo marroquí en las crónicas de José María Sevillano (1925-1926)
Authors: Parejo Delgado María Josefa
Published: March 2019

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La voz y la mirada de la mujer musulmana
Authors: Monjas Hernández Oñez
Published: March 2019

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Feminismo y las técnicas de reproducción asistida
Authors: Puigpelat Martl Francesca
Published: March 2019

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Cuidados paliativos y eutanasia: especial referencia a la legislación belga
Authors: Marcos del Cano Ana María
Published: March 2019

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Introducción
Authors: Megías Aznar José
Published: March 2019

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Las menores extranjeras no acompañadas en Melilla: ¿menores o extranjeras?
Authors: Escámez Pastrana Marisa
Published: March 2019

Este artículo es una versión breve del Trabajo Fin de Máster Oficial en Problemas Sociales, leído en Madrid el 28 de Septiembre de 2011 y valorado con Matrícula de Honor por el Tribunal calificador. Se trata de un trabajo previo al Doctorado en Análisis de los Problemas Sociales.
Política turística de un destino singular: Melilla (España)
Authors: González Fernández Virgilio , López-Guzmán Tomás
Published: March 2019

La sostenibilidad o no del turismo de una determinada área geográfica, depende, en gran medida, de la política que las autoridades públicas lleven a cabo en la mencionada área. También, la realidad nos enseña que la imagen turística tiene bastante que ver con el buen hacer de los poderes públicos. Es obvio que una y otra no dependen exclusivamente de lo que hacen las Administraciones Publicas, ya que no son los únicos agentes que intervienen; aunque sí es bastante cierto ya que tiene un peso considerable. El caso de Melilla es, al menos, razonablemente atípico en lo que se refiere tanto a la sostenibilidad como a la imagen de esta ciudad como destino turístico. Por ello, el objetivo de este artículo no es otro que mostrar una serie de factores y de problemas, sobre los que se tendría que incidir, para hacer viable y sostenible un destino turístico que hoy no lo es y, a la vez, mejorar una imagen, que no responde a la realidad.The sustainability of tourism in a particular geographic area depends to a large extent on the political public authorities carry out in that area. Also, the reality teaches as that tourism image has a lot to do with the good of the public authorities. It is obvious that this image also depends on the enterprises. The case of Melilla is at least reasonably unusual in regards to both the sustainability and the image of this city as a tourist destination. Therefore, our proposal is show a number of factors and problems which would have to work to make viable and sustainable tourist destination that today is not and, in turn, improve an image which no correspond to reality.
Las islas Chafarinas a través de la cartografía. Del siglo XVI a la ocupación
Authors: Gámez Gómez Sonia
Published: March 2019

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De las tres ínsulas a Jafarín. Las islas Chafarinas y su entorno en la antigüedad y medievo
Authors: Aragón Gómez Manuel
Published: March 2019

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Sociedad y vida cotidiana en las islas Chafarinas
Authors: Lechado Granado María del Carmen
Published: March 2019

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Un templo de tradición neoclásica en el norte de África. La iglesia de la Inmaculada Concepción de Chafarinas
Authors: Bravo Nieto Antonio
Published: March 2019

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Algunos aspectos de la proclamación de la República en Melilla : Abril Elecciones Municipales, 1931
Authors: Bravo Nieto Antonio
Published: March 2019

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Maimónides, pensamiento, influencia y actualidad
Authors: Delgado Feliciano
Published: March 2019

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Transcripción del índice de disposiciones de esta obra. Índice de los documentos que comprehende este Tomo
Authors: - -
Published: March 2019

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Introducción : escribir nuestra historia
Authors: Moga Romero Vicente
Published: March 2019

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El proceso Berenguer : Sus efectos en Melilla
Authors: González Sánchez José Javier
Published: March 2019

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Los Ingenieros Militares en el Urbanismo de Melilla
Authors: Rodríguez Puget Joaquín
Published: March 2019

Aseverar que el urbanismo en Melilla es anárquico en sus orígenes o aban donado a la improvisación en su planteamiento, es tan contrasentido como atribuir a cualquier técnico ajeno a la arquitectura militar, la regularidad y ar monía del trazado del Ensanche de Melilla. Decir que sólo una ciudad de Europa, la Hermosa Viena, salvando por supuesto su monumentalidad y pro porción, puede asemejarse en su estructuración a Melilla, no es, en mucho, un atrevimiento, pues en ella, en la capital de los archiduques, ya en el siglo XIX, se arrasan lienzos de murallas y bastiones para abrir camino al Ring de Viena, cinturón de bulevares que rodean la Ciudad Interior. En Melilla, a comienzos del siglo XX, se destruyen torreones, lienzos, fosos y camino cubierto del Cuarto Recinto defensivo para dejar sitio a las principales avenidas y paseos del Ensanche. Al igual que Viena acomete grandes obras de regularización del Danubio para defenderse de sus frecuentes y catastróficas inundaciones, Melilla a me diados del siglo XIX desvía y encauza el Río de Oro con idéntico objetivo. El Volksgarten de Viena se levanta en 1809 sobre los cimientos de la anti guas fortificaciones; el espléndido Parque Hernández de Melilla surge como consecuencia de un plan de defensa que sacrifica el campo de maniobra, pro tegido por el Cuarto Recinto, para su emplazamiento. Asimismo, el marco modernista en que se encuadra Melilla, proyectado por Enrique Nieto, arquitecto catalán y discípulo de Gaudí afincado en Meli lla desde 1909, ha dado lugar a una corriente de opinión, muy generalizada, de atribuirle notable influencia en el trazado de sus arterias y perfecta retícula de sus barrios, y hasta la paternidad de su urbanismo, cuando su trazado se debe única y exclusivamente a las previsiones y bien hacer de los ingenieros milita res, como a continuación establezco a través de los datos extraídos de la Co mandancia de Ingenieros, sede de los artífices de Melilla.
La desorganización organizada de la institución escolar
Authors: Martín Rodríguez Eustaquio
Published: March 2019

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Evaluation of the Effects of Periodontal Disease Severity on Social Anxiety Level
Authors: SARI Ayşegül , ŞENYURT Süleyman Ziya , ÜSTÜN Kemal , KUL Seval , ERCİYAS Kamile
Published: March 2019

Objectives: The aim of this study was to determine the level of social anxiety in patients with periodontal disease, and to examine its relationship with the clinical characteristics of periodontal disease.Materials and Methods: This study investigated 200 patients in a cross-sectional design. Sociodemographic data, clinical periodontal parameters and patient complaints were recorded. Patients were divided into four groups according to their clinical periodontal index values: chronic periodontitis (CP), aggressive periodontitis (AP), gingivitis (G), and periodontally healthy (PH). Social anxiety levels of the patients were assessed based on the Liebowitz Social Anxiety Scale (LSAS).Results: A negative relationship was observed between LSAS scores and age, a positive relationship was observed with education level (p0.05). The Liebowitz total score and total anxiety, socially related anxiety and total avoidance levels of patients with halitosis complaints were found significantly higher (p0.05). LSAS scores for patients with complaints of aesthetics and mobility were significantly higher for all seven sub-items (p0.05). Total avoidance and performance avoidance values were significantly higher in patients with complaints of gingival bleeding (p0.05). All of the LSAS scores were higher in the AP and CP groups compared to the PH group and higher in the AP group than in the CP and G groups (p<0.05). In the G group, the performance-related avoidance level was significantly higher than in the PH group (p<0.05).
Prepress Alderdommens pædagogisering
Authors: Nørtoft Kamilla
Published: March 2019

Denne artikel handler om pædagogisering af alderdommen og ældre mennesker. Pædagogik forekommer på mange forskellige niveauer, og ofte giver ordet associationer til opdragelse, dannelse og uddannelse af børn og institutionaliserede unge og voksne. Det danske samfunds pædagogiske tiltag overfor ældre mennesker handler oftest om sundhed på den ene eller den anden måde. Ældrepædagogik bliver således til sundhedspædagogik. Det handler om at få folk til at arbejde aktivt på at holde sig sunde og friske for at modvirke den såkaldte ældrebyrde, som ifølge visse diskurser om den demografiske udvikling er som en bombe under vores samfund. Denne diskurs tager udgangspunkt i forestillingen om den naturlige aldring og en medicinsk forståelse af cellernes uundgåelige degenerering. Mens ældre mennesker således fra forskellige sider opfordres til at holde sig sunde og aktive for at udsætte det forestillede forfald så længe som muligt, bliver yngre ældre mennesker også opfordret til at forholde sig til den dag, hvor udsættelsen ikke længere er aktuel, men forfaldet er indtrådt. Dette kan f.eks. ske ved at fremtidssikre deres bolig med fysiske foranstaltninger, der gør den tilgængelig og håndterbar – selv for folk med fysiske funktionsnedsættelser. I artiklen vil jeg kaste lys over ældrepædagogikken på to niveauer; et politiko-økonomisk niveau repræsenteret ved forskellige former for politiske mål og retningslinjer og et relationsniveau repræsenteret af de medarbejdere, som møder ældre borgere i deres kontakt med velfærdssamfundet. De to niveauer er ikke isoleret fra hinanden, og særligt det relationelle niveau er i forskellige grader rammesat af det politiko-økonomiske niveau, som dog alligevel efterlader et vist manøvrerum for mellemmenneskelige relationer i den pædagogiske praksis. Efter en kort introduktion til ældrepædagogik som felt, der bevæger sig mod sundhedspædagogik, og til eksempler på politikudvikling inden for ældreomsorgen, vil jeg præsentere tre forskellige ældrepædagogiske perspektiver: a) vellykket aldring, b) selvstændig læring og udvikling under vejledning og uddannelse og c) bæredygtig aldring. Jeg vil illustrere de tre perspektiver med eksempler fra forskellige ældrepædagogiske praksis- og fagfelter og vise, hvordan de kan forstås ud fra det politiko-økonomiske og/eller det relationelle pædagogiske niveau. Perspektiverne er baseret på etnografiske studier af ældrepædagogiske sammenhænge, politikker og tværfaglige personaleteams’ forståelser af professionelles opgaver og roller i forhold til deres målgrupper. Analysen viser, hvordan pædagogiske tilgange baseres på forskellige værdisæt og måder at at identificere ældre mennesker på.
New Universities’ Organizational Identities Through Presidential Lenses
Authors: Levin John S. , López Damián Ariadna I. , Martin Marie C. , Vázquez Evelyn M.
Published: March 2019

This qualitative investigation addresses three new universities in the provinces of British Columbia and Alberta and their presidents’ ascriptions of organizational identity to their universities. Through extended, semi-structured interviews and narrative analysis, this investigation uses organizational identity theory and institutional theory to explain the positionality and understandings of presidents in relationship to their universities’ paths to legitimacy. We found that the preservation of aspects of the institutions’ original identity (as community colleges) aids new universities’ organizational change. Furthermore, while presidents advocated for a replacement of community college logics with university logics, data showed that these three new universities had yet to embrace the university logic fully. We propose that a blending of logics may be the preferred mechanism for the attainment of legitimacy during sectoral change for new universities.This qualitative investigation addresses three new universities in the provinces of British Columbia and Alberta and their presidents’ ascriptions of organizational identity to their universities. Through extended, semi-structured interviews and narrative analysis, this investigation uses organizational identity theory and institutional theory to explain the positionality and understandings of presidents in relationship to their universities’ paths to legitimacy. We found that the preservation of aspects of the institutions’ original identity (as community colleges) aids new universities’ organizational change. Furthermore, while presidents advocated for a replacement of community college logics with university logics, data showed that these three new universities had yet to embrace the university logic fully. We propose that a blending of logics may be the preferred mechanism for the attainment of legitimacy during sectoral change for new universities.
Academic Drift in Canadian Institutions of Higher Education: Research Mandates, Strategy, and Culture
Authors: Trotter Lane D. , Mitchell Amy
Published: March 2019

As with higher-education institutions around the world, British Columbia (BC) and Ontario are increasingly faced with demographic and market pressures that erode the traditional difference between the university and non-university sectors (i.e., colleges and institutes). Key components that ensure these provinces’ institutions preserve their unique roles and differentiations in a changing context, partially driven by their governments, include research mandates, transparency in institutional governance, and strategic documents that resist the academic drift created by institutional isomorphism. Both governments are actively reshaping their post-secondary systems to align with national or regional economic needs, increasing access, streamlining degree completion, and responding to community pressure to have a university or a degree-granting institution. An analysis of the enabling legislation, government policy directives, and institutional documents of both provinces shows that there is a blurring in the distinction between colleges and universities, and the costs associated with this.
Experiences of Food Insecurity Among Undergraduate Students: “You Can’t Starve Yourself Through School”
Authors: Maynard Merryn Sanders , Meyer Samantha B , Perlman Christopher M , Kirkpatrick Sharon I
Published: March 2019

Canadian post-secondary students are vulnerable to food insecurity, yet lack of examination of this issue has prevented identification of policy and program solutions. This mixed-methods study aimed to characterize the experience of food insecurity among undergraduate students by eliciting barriers to food security, strategies used to manage food and money shortages, and perceived implications for health and academic achievement. Surveys and in-depth interviews were conducted with 14 students who demonstrated compromised financial access to food. Students normalized experiences of food insecurity as typical of post-secondary education but expressed anxiety and frustration with financial inaccessibility to healthy food, and described negative implications for their physical and mental health and their ability to perform well in school. Ongoing attempts to adapt or adjust to food insecurity had limited success. Findings highlight the need to challenge the “starving student” ideology, which normalizes the lack of access to healthy food during higher education.
Determination of two fluoroquinolones and their combinations with hyaluronan effect inin vitrocanine cartilage explants
Authors: Siengdee Puntita , Pradit Waranee , Chomdej Siriwadee , Nganvongpanit Korakot
Published: March 2019

Background

Previous studies reported the effect of enrofloxacin (Enro) and marbofloxacin (Mar) on cell death and alteration of the key genes involved in catabolic and anabolic processes and demonstrated the beneficial effects of hyaluronan (HA) combined with fluoroquinolones (FQs) on primary canine chondrocytes. This study further determines the effects of these treatments on canine cartilage explants in both normal and interleukin-1 beta (IL-1β)-stimulated conditions.

Methods

We examined sulfate glycosaminoglycan (s-GAG) release, uronic acid (UA) content, and safranin-O staining, as well as the expression patterns of inflammatory, extracellular matrix (ECM) component and enzymes.

Results

Enro treatment alone effectively stimulated proteoglycan anabolism by increasing UA content and glycosaminoglycans (GAGs) in normal and pre-IL-1β-stimulated explant, whereas Mar showed opposite results. The combination of HA and FQs increased s-GAG release and UA content in normal explants in addition to effective down-regulated expression ofMMP3. HA reduced the adverse effects of Mar by enhancing UA and GAG contents in both normal and pre-IL-1β-explants. Moreover, HA effectively inducedHAS1andACANup-regulation and reducedMMP9, TNF, PTGS2,andNFKB1expression for a long term.

Discussion

Our results suggest the direct effects of Enro and Mar may selectively stimulate the conditioned explants to express MMP-codinggenes and promote gene expression involved in matrix production, pro-inflammatory cytokines, and cell degradation in different directions. HA successfully reduced the adverse effects of FQs by enhancing s-GAG and UA contents and down-regulated expression of MMPs.
Performance Evaluation of Some Rice Varieties under the System of Planting in Egypt
Authors: Khattab E. A.
Published: March 2019

Rice is planting in different ways in Egypt; including direct seeding and transplanting seedling, so most of farmers facing problems in select any method and variety which may be led to highly income. Experiments ware conducted carried out during summer season at years 2016 and 2017, in privet Farm in east Delta Egypt, to investigate production of three varieties of Rice (Sakha 102, Giza 178 and Giza 182), affected by two sowing methods (direct seeding and seedling transplanting) under treatment of NPK concentration (0.0, 2% and 4%) as form 20:20:20 NPK, were arranged in split split-plot design with three replications. The results showed the superiority of the method of planting on the method of planting in both seasons. Increase in NPK concentration with Giza 178 under direct seeding recorded highly data for vegetative and physiology parameter; yield and yield component, and contents from some chemical contents in leaves and grains, while all parameter in this study recorded lowest data with Giza 182 under control NPK and transplanting.
Olive Oil‐Based Ultrafine Theranostic Photo Nanoemulsions: A Versatile Tumor Maneuvering Nanoplatform for Precise Controlled Drug Release in Tumor and Complete Tumor Eradication Mediated by Photo‐Chemotherapy
Authors: Rejinold N. Sanoj , Cherukula Kondareddy , Ha Jong Hoon , Park In‐Kyu , Kim Yeu‐Chun
Published: March 2019

Photothermal therapy (PTT) is an efficient approach to treat tumors. However, heterogeneous distribution of heat by PTT in the tumor region often results in tumor regrowth and metastasis. Integrating PTT with chemotherapy in a precisely controlled tumor maneuvering and drug‐releasing nanoconstruct will be an ideal strategy for higher therapeutic index. Herein, nanoemulsions (NEMSn) based on a highly biocompatible extra virgin olive oil are developed to encapsulate IR‐780 for PTT and near infrared fluorescence imaging as well as doxorubicin (DOX) for chemotherapy. NEMSn are further stabilized with Tween‐20 and hyaluronic acid to form an ultrafine theranostic photo nanoemulsions (UTPNEMSn) for combinatorial photo‐chemotherapy. Once injected into the system, UTPNEMS homes to the tumor region owing to passive targeting. Tumor accumulated UTPNEMSn readily destabilizes upon laser irradiation to release the DOX, thereby synergizing the therapeutic effects of DOX and PTT. In vivo studies demonstrate a complete tumor eradication without tumor recurrence or systemic toxicity, owing to their biocompatible formulation. By virtue of the olive oil based NEMSNs and precise controlled drug releasing properties collaborating with the synergistic therapeutic modalities, UTPNEMSn are able to provide a promising method for controlled drug delivery systems.
High‐Performance Relaxor Ferroelectric Materials for Energy Storage Applications
Authors: Zhao Peiyao , Wang Hongxian , Wu Longwen , Chen Lingling , Cai Ziming , Li Longtu , Wang Xiaohui
Published: March 2019

Relaxor ferroelectrics usually possess low remnant polarizations and slim hystereses, which can provide high saturated polarizations and superior energy conversion efficiencies, thus receiving increasing interest as energy storage materials with high discharge energy densities and fast discharge ability. In this study, a relaxor ferroelectric multilayer energy storage ceramic capacitor (MLESCC) based on 0.87BaTiO3‐0.13Bi(Zn2/3(Nb0.85Ta0.15)1/3)O3 (BT‐BZNT) with inexpensive Ag/Pd inner electrodes is prepared by the tape casting method. The MLESCC with two dielectric layers (layer thicknesses of 5 µm) sintered by a two‐step sintering method exhibits excellent energy storage properties with a record‐high discharge energy density of 10.12 J cm−3, a high energy efficiency of 89.4% achieved at an electric field of 104.7 MV m−1, a high temperature stability of the energy storage density (with minimal variation of <±5%), and energy efficiency (>90%) over a range of −75 to 150 °C at 40 MV m−1. These results suggest that the BT‐BZNT relaxor ferroelectric ceramic material can provide realistic solutions for high‐power energy storage capacitors.
Disordered, Large Interlayer Spacing, and Oxygen‐Rich Carbon Nanosheets for Potassium Ion Hybrid Capacitor
Authors: Chen Jiangtao , Yang Bingjun , Hou Hongjun , Li Hongxia , Liu Li , Zhang Li , Yan Xingbin
Published: March 2019

Potassium ion storage technology as a promising substitute for the well‐developed lithium ion storage technology is still at the infancy stage of development, and exploring suitable electrode materials is critical for its practical application. Here, the great feasibility of disordered, large interlayer spacing, and oxygen‐rich carbon nanosheets (CNSs) prepared by chemical vapor deposition for potassium ion storage applications is demonstrated. As an anode material, the CNSs exhibit outstanding rate capability as well as excellent cyclic stability. Taking advantage of this, a potassium ion hybrid capacitor (PIHC) is constructed by employing such CNSs as the battery‐type anode and activated carbon as the capacitor‐type cathode. The resulting device displays a high energy density of 149 Wh kg−1, an ultrahigh power output of 21 kW kg−1, as well as a long cycling life (80% capacity retention after 5000 cycles), which are all close to the state‐of‐the‐art values for PIHCs. This work promotes the development of high‐performance anode material for potassium ion storage devices, and the designed PIHC pushes the energy density and power density to a higher level.
Current status of postoperative infections after digestive surgery in Japan: The Japan Postoperative Infectious Complications Survey in 2015
Authors: Niitsuma Toru , Kusachi Shinya , Takesue Yoshio , Mikamo Hiroshige , Asai Koji , Watanabe Manabu
Published: March 2019

Aim

To survey postoperative infections (PI) after digestive surgery.

Methods

This survey, conducted by the Japan Society of Surgical Infection, included patients undergoing digestive surgery at 28 centers between September 2015 and March 2016. Data collected included patient background characteristics, type of surgery, contamination status, and type of PI, including surgical site infection (SSI), remote infection (RI), and antimicrobial‐resistant (AMR) bacterial infections and colonization.

Results

Postoperative infections occurred in 10.7% of 6582 patients who underwent digestive surgery (6.8% for endoscopic surgery and 18.7% for open surgery). SSI and RI, including respiratory tract infection, urinary tract infection, antibiotic‐associated diarrhea, drain infection, and catheter‐related bloodstream infection, occurred in 8.9% and 3.7% of patients, respectively. Among all PI, 13.2% were overlapping infections. The most common overlapping infections were incisional and organ/space SSI, which occurred in 4.2% of patients. AMR bacterial infections occurred in 1.2% of patients after digestive surgery and comprised 11.5% of all PI. Rate of AMR bacterial colonization after digestive surgery was only 0.3%.

Conclusion

Periodic surveillance of PI, including AMR bacteria, is necessary for a detailed evaluation of nosocomial infections.
Accelerating chimeric antigen receptor therapy in chronic lymphocytic leukemia: The development and challenges of chimeric antigen receptor T‐cell therapy for chronic lymphocytic leukemia
Authors: Bair Steven M. , Porter David L.
Published: March 2019

Studies of chimeric antigen receptor (CAR) T‐cell therapy in chronic lymphocytic leukemia (CLL) have demonstrated the potential to produce deep remissions—and possibly cures—in some patients with heavily pretreated, high‐risk, relapsed, and refractory disease. Unfortunately, most clinical trials of CAR T cells in CLL report complete responses only in the minority of patients, although recent studies have begun to elucidate the factors most predictive of response. These studies have suggested strategies for optimizing CAR T‐cell fitness as well as the pre‐existing host immune response, approaches that will likely lead to improvements in the efficacy of CAR T cells in CLL. Treating patients earlier in the course of their disease or using combination therapies with CAR T cells may further enhance efficacy. In this review, we summarize the existing literature on CAR T cell therapy in CLL, discuss mechanisms of response and resistance, and describe challenges facing the field.
Knockout of ISCA1 causes early embryonic death in rats
Authors: Yang Xinlan , Lu Dan , Zhang Xu , Chen Wei , Gao Shan , Dong Wei , Ma Yuanwu , Zhang Lianfeng
Published: March 2019

Background

Iron‐sulfur cluster assembly 1 (ISCA1) is an iron‐sulfur (Fe/S) carrier protein that accepts Fe/S from a scaffold protein and transfers it to target proteins including the mitochondrial Fe/S containing proteins. ISCA1 is also the newly identified causal gene for multiple mitochondrial dysfunctions syndrome (MMDS). However, our knowledge about the physiological function of ISCA1 in vivo is currently limited. In this study, we generated an ISCA1 knockout rat line and analyzed the embryo development.

Methods

ISCA1 knockout rats were generated by replacing the exon1 of ISCA1 gene with the mCherry‐Cre fusion gene using CRISPR‐Cas9 technology. The ISCA1 expression pattern was analyzed by fluorescence imaging using ISCA1 promotor driven Cre and mCherry expression. The embryonic morphology was examinated by microscope and mitochondrial proteins were tested by Western blot.

Results

An ISCA1 knockout rat line was obtained, which expressed mCherry‐Cre fusion protein. Both of the fluorescence images from mCherry and Cre induced mCherry in a reporter rat strain, showing that ISCA1 expressed in most of the tissues in rats. The ISCA1 knockout resulted in abnormal development at 8.5 days, with a significant decrease of NDUFA9 protein and an increase of aconitase 2 (ACO2) in rat embryos.

Conclusion

Deletion of ISCA1 induced early death in rats. ISCA1 affected the expression of key proteins in the mitochondrial respiratory chain complex, suggesting that ISCA1 has an important influence on the respiratory complex and energy metabolism.