bluuebunny/crossref_metadata_2025 huggingface dataset:
Rumble Strips: A Human Factors Perspective towards a Sustainable Road System
Authors:   Universiti Malaysia Sarawak, Malaysia, Zaidi Adruce Shahren Ahmad , Stephen Donald ,   Universiti Malaysia Sarawak, Malaysia
Published: February 2023

Prior research substantiates the belief that human factors contribute to up to 90% of all traffic accidents. The failure to consider cognitive ergonomics in road safety initiatives will continue to cause traffic fatality, especially on straight roads. Since drivers and road safety practitioners cannot wholly avoid driver’s non-compliance, skill-based errors, and mistakes, road designs should aim to reduce the severity of repercussions resulting from human errors. For example, in the case of a momentary lapse of attention leading to lane departure, drivers should be able to correct their maneuvers. A human-centered traffic system approach of road design may reduce the severity of accidents caused by human error. An investigation of road crashes in Malaysia conducted by the Malaysian Institute of Road Safety Research revealed that 66% of road crashes in Malaysia are opposite-direction head-on crashes and run-off-road (roadway departure) crashes. Installing Lane Departure Warning System such as Centerline Rumble Strips (CLRS) and Shoulder Rumble Strips (SRS) can reduce these types of crashes and compensate human errors on the road. Rumble strips alert drivers that they are deviating from their lane by providing both tactile and auditory warnings. Although the effectiveness of rumble strips is well documented in prior researches, the practice of installing rumble strips is still scarce in Malaysia. This paper highlights how rumble strips can mitigate the consequences of the human errors, in the hope that the information can help road safety researchers, authorities, and practitioners move forward in the implementation of interventions towards sustainable road system.
Corrosion Resistance Evaluation of Acrylic Coating Incorporated With Henna Leaves Extract
Authors:   Materials and Corrosion Research Group, Faculty of Ocean Engineering Technology and Informatics, Universiti Malaysia Terengganu, Malaysia, Ridwan Zulkifli Mohammad Fakhratul , Mohd Ghazali Mohd Sabri ,   Advanced Nano Materials (AnoMa) Research Group, Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, Malaysia, Mohamad Isa Mohd Ikmar Nizam ,   Frontier Materials Research, Faculty of Science and Technology, Universiti Sains Islam Malaysia, Malaysia, Mat Jusoh Suriani ,   Materials and Corrosion Research Group, Faculty of Ocean Engineering Technology and Informatics, Universiti Malaysia Terengganu, Malaysia, Yabuki Akihiro ,   Graduate School of Engineering, Hiroshima University, Japan, Wan Nik Wan Mohd Norsani ,   Materials and Corrosion Research Group, Faculty of Ocean Engineering Technology and Informatics, Universiti Malaysia Terengganu, Malaysia
Published: February 2023

The study employs optical measurements, electrochemical studies and mechanism evaluations of an acrylic coating incorporated with henna leaves extract (HLE) at ambient temperature. The effect of concentrations variation of HLE in acrylic coating was investigated and acrylic coating with 0.2 wt/vol% (AC2) of HLE had the best performance protecting aluminium alloy 5083 from corrosion. Characterization through Fourier Transform Infrared Spectroscopy (FTIR) demonstrates the association of the carbonyl group of lawsone with the acrylic resin polymer via chain scission. A further deconvolution method was used in the range of 1550 – 1720 cm-1 and the complexation between HLE and acrylic coating was observed due to the shifting of carbonyl peak. AC2 shows the lowest water permeability value due to the compact structure and high density of the HLE colloidal system. Coating resistance shows an increasing trend upon incorporation of HLE and reaches the maximum resistance at AC2. A circuit fitting analysis of electrochemical impedance spectroscopy (EIS) indicates that all coated samples is represented by [(RfQdl)(RctQdl)(W)] circuit. Warburg impedance, W for AC2 shows the lowest value (1.21 × 10-7 Ω.s-1/2) in comparison to the other samples which indicates lower speed of diffusion. Suggested mechanism shows that HLE in AC2 was formed in a close pack structured in which providing a greater barrier effect towards corrosion susceptibility of aluminium alloy 5083.
Perceptions of Public and Professional on Visual Image of Putrajaya City
Authors:   Fakulti Rekabentuk dan Senibina, Universiti Putra Malaysia (UPM), Malaysia, Abd. Rahim Fazlena , Tolba Said Mohamed Mohamed ,   Kuliyyah of Education, International Islamic University Malaysia (IIUM), Malaysia.
Published: February 2023

Putrajaya is the federal government's administrative center which at the beginning of its development was planned as an Islamic city. The objective of this study is to analyze the visual images of the built environment that give the identity of Putrajaya based on public and professional perceptions. Modernization and lack of understanding of the interpretation of Islamic architecture has resulted in an identity crisis in the architectural style, misleading identity and affected the identity of the Islamic city. This study adopts both quantitative and qualitative methods. A questionnaire survey involving 500 civilians and photo-base method interviews with 100 professionals in the field of built environment was conducted to analyze the identity and the visual image of Putrajaya. The findings show that Putrajaya's urban design has a high aesthetic value and Islamic culture through the Islamic Middle East features to realize its application as an Islamic city. However, the style of modern that dominates, mixture, diversity and lack of local identity creates a misleading and a weak of cultural identity. The findings of this study can be utilized to strengthen the visual image of Putrajaya city as an Islamic city with its own local identity and identity to increase attractiveness to urban users.
Clustering Approach on Layout Redesign to Optimize Container Handling Process
Authors:   Industrial Engineering Departement, Sultan Agung Islamic University, Indonesia, Sugiyono Andre
Published: February 2023

Container Terminal of Semarang is a service provider for export and import container handling process. It represents one of the divisions of PT (Persero) Port of Indonesia III Branch TanjungEmas Semarang. As an anticipatory step to growth of containership capacity in Port of Indonesia III Semarang, the company need to improve the quality of container handling service and to reach a higher level of productivity. One of the ways to achieve these goals is to focus on layout planning and management that can potentially be beneficial to all factors involved such as space exploitation, process efficiency etc. The layout planning of a container terminal can significantly benefit from using Group Technology approach in which containers can be grouped into families of containers and transported between cells(block locations in the yard).With this type of layout, the company has many advantages like flexibility on production process to address high variability in the system. As a result, it can give alternative arrangement of container in the yards. We observed that based on Bond Energy Algorithm (BEA) method, container travel distance can be reduced to 188.06 metres/ month, which is approximately 9 % saving of distances travelled by each container. Moreover, using Group Technology approach can provide a higher flexibility to cope with fluctuations in process.
Variability in nonlinear sediment response during the 1994 Northridge, California, earthquake
Authors: Hartzell Stephen
Published: February 2023

Spectral ratios between sediment sites and rock sites for strong and weak ground motion are compared to infer the extent of nonlinear sediment response in the Los Angeles area during the 1994 Northridge earthquake. Northridge mainshock records form the strong-motion database and aftershock records form the weak-motion database. The degree of nonlinearity is evaluated at 25 locations in and around the San Fernando and Los Angeles Basins based on the ratio of weak-to-strong spectral amplification factors (WSAF). Values of WSAF vary greatly from site to site and, for a given site, from one frequency band to another over the range from 0.75 to 20 Hz. This complexity is attributed to differences in several factors: material properties under the sites and the amplitude and frequency content of the input ground motions. Given these observations, it is not possible to assign an acceleration or velocity level at which nonlinearity initiates for all the stiff soil sites analyzed. However, no nonlinearity is seen below a peak acceleration of about 200 to 300 cm/sec2 or peak velocity of 20 to 30 cm/sec. Nonlinearity is seen at all sites in or near the San Fernando Valley. Nonlinearity in the Los Angeles Basin is limited to a few isolated sites. For the Northridge earthquake, even sites with strong nonlinearity still show amplification levels greater than 1.0 relative to rock sites for frequencies below 10 Hz.
Compressional and shear velocity structure of the lithosphere in northern Iceland
Authors: Menke William , West Michael , Brandsdóttir Bryndís , Sparks David
Published: February 2023

Seismic data from the B96 array in northern Iceland are used to constrain the compressional and shear velocity structure of the crust and uppermost mantle in northern Iceland, at the western flank of the northern volcanic zone (NVZ) (the mid-Atlantic plate boundary in northern Iceland). Travel times from P and S waves from shots and microearthquakes north and south of the array are used. Two dome structures, with velocities 6% faster than average, are detected at depths down to 7 km. They may be the fossil roots of extinct central volcanoes. P, S, PmP, and SmS wave travel times indicate that the compressional-to-shear-wave velocity ratio in the crust is 1.75 to 1.76, with no significant variation detected between the mid and lower crust. Near-solidus lower crustal temperatures, previously predicted on the basis of high surface heat flow, are ruled out. The crust is 25 to 31 km thick, with the southward thickening occurring in an abrupt step. The relatively high Pn and Sn wave apparent velocities of 8.00 ± 0.1 km/sec and 4.31 ± 0.04 km/sec, respectively, from an earthquake in southern Iceland, are consistent with a mantle lid, that is, a layer of subsolidus mantle separating the Moho from a deeper, partial melt zone. Travel times from P waves crossing the NVZ from a fan shot in eastern Iceland cross the previously identified Krafla high-velocity dome at a depth of 8 to 10 km. They provide new support for the existence of this mid-crustal feature and indicate that its base extends 40 to 50 km along the strike of the NVZ. The neighboring Þeistareykir central volcano has no dome at 8 to 10 km depth, suggesting that it has had a more subsidiary role in the formation of the lower crust.
Neurological manifestations of multisystem inflammatory syndrome in children associated with COVID-19 in a tertiary care centre
Authors: Chintha Lakshman , Magar Suvarna , Vaidya Varsha , Bhartiya Shirish , Mehta Krishna
Published: February 2023

Multisystem inflammatory syndrome in children (MIS-C) and adolescents temporally related to COVID-19” is a new entity characterized by fever, multisystem organ involvement, laboratory evidence of inflammation, and laboratory or epidemiological evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, in individuals aged 0–19 years with no alternative diagnosis. Neurological manifestations are not part of the diagnostic criteria of MISC and hence remain poorly described. So, we wanted to note down the neurological involvement in multisystem inflammatory syndrome in children (MIS-C) related to severe acute respiratory syndrome with coronavirus infection. Here we describe 6 cases of COVID MISC who presented as acute febrile illness with drowsiness, irritability, convulsions and serious ones with encephalopathy. Focal neurological signs, abnormal brain magnetic resonance imaging (MRI) was present in four patients. MRI brain was normal in 2 cases CSF study was normal in all cases. These patients received intravenous methylprednisolone at 30 mg/kg/day for 3 days. Cases 3 to 6 were given intravenous immunoglobulin (IVIG), the clinical picture rapidly improved in the first three days, and all neurological symptoms disappeared within 10 and 30 days with some sequel in cases 4 to 6. In conclusion we describe clinical and laboratory parameters in these patients with neurological manifestations and we documented an increase in pro inflammatory markers correlating with severity of neurological presentation in children with MISC. High index of suspicion is needed to diagnose neurological manifestations of MISC following COVID-19 pandemic. Neurological spectrum can be broad range of manifestations though outcome was favorable with early treatment.
An unusual case of meat bolus impaction in an adult
Authors: Malhotra Sonali
Published: February 2023

Esophageal food impaction is a common emergency faced by ENT surgeons and gastroenterologists. It is important to know what techniques and instruments are indicated for different situations. Endoscopic treatment is a reliable and safe procedure in skilled, expert hands with a high success rate and low morbidity and mortality.
Mandibular adenomatoid odontogenic tumor: case report
Authors: Bali Kulbhushan , Das Deepthy , Prasad Babu Rajendra , Lakshmi Sai
Published: February 2023

Adenomatoid odontogenic tumor (AOT) is a rare tumor of epithelial origin which accounts for 3% of odontogenic tumors. The most common area of involvement is the maxilla, about 65% of cases, followed by the mandibular region accounting to 35% of cases. This case report is of a 16 year old girl operated and diagnosed with AOT at the anterior aspect of the mandible. This case report also discussed about the necessity for a detailed descriptive, differentiating features of AOT from other odontogenic tumors, the most common misdiagnosis being dentigerous cyst.
The Preparation and Physicochemical Analysis of Local Black Soap from Coconut Oil and Plantain Peel Biochar
Authors: NNYİA Mary Otuosorochukwu , OLADİPO Abiodun , ANYAEBOSİM Ebube Victoria , EJEROMEDOGHENE Onome
Published: February 2023

Local black soap, produced from coconut oil and plantain peel biochar (alkaline source) was presented in this study since the agricultural raw materials gain significance in environmentally benign feedstocks for saponification reactions. The physicochemical analysis of the coconut oil and plantain peel biochar shows remarkable free fatty acid (FFA) and alkalinity contents respectively suitable for soap making. The physicochemical properties of the as-prepared local black soap demonstrated a good moisture content (15.1 %) showing that it can be stored for long periods without any water-associated deteriorations. The percentage of matter insoluble in water (4.4 %), matter insoluble in alcohol (12.3 %), FFA content (2.1 %), and pH (9) were found to be higher than the acceptable limit according to the Nigerian Industry Standards (NIS). Also, the total fatty matter (TFM) was higher (67.6 %) than the minimum acceptable level with a good foam height of 2.5 cm. The overall results show good soap properties and are suitable for domestic purposes.
Assessing food security status of rural households in North Eastern Nigeria: A comparison of methodologies
Authors:   University of Ibadan, Oyediran IO , Olajide OA
Published: February 2023

This study analyzed food security status of rural households in North Eastern Nigeria. Secondary data were employed. The data were accessed from the General Household Survey (GHS) for years 2013 and 2016, waves 2 and 3. 451 households were considered in each wave. The objective of the study was to determine the food security status of rural households, analyze factors influencing their food security and compare the output of different methodologies used to measure food security during the periods. Frequency and Percentages were used to analyze the socioeconomic characteristics of respondents. Mean per Capita Food Expenditure (MPCE), Dietary Diversity Score (DDS), Foster, Greer and Thorbecke (FGT) index were used to analyze household food security status while Logit regression model was used to analyze factors influencing household food security status. Results from the descriptive statistics showed that male household heads, married household heads and literate household heads were food secure in both waves. Results from Mean per Capita Food Expenditure (MPCE), and Foster, Greer and Thorbecke (FGT) showed that more than half of the selected households were food secure in both waves but reverse was the case with Dietary Diversity Score (DDS). Age, level of education, and household size were found to be factors influencing food security in both waves and models. The results from the logistic regression showed that an increase in age of household head and household size will reduce the food security status of the North-Easterner’s rural households. Also, the result revealed that the food security status was higher in Borno, Gombe and Yobe compared to Taraba and tertiary education increased the level of food security status for MPCE but reduced the same for DDS. Based on these findings, the study recommends sensitizations on the importance of education and family planning for the rural household in North Eastern states of Nigeria. Key words: Food security status, rural household, North Eastern Nigeria
Nutritional composition and cytotoxicity studies of black monkey (Strychnos madagascariensis) ripe fruit
Authors:   University of Zululand, Oboh M , Zharare G , Osunsanmi F , Mosa R ,   University of Pretoria, Opoku A
Published: February 2023

Strychnos madagascariensis also known as black monkey orange is found in tropical and subtropical Africa including South Africa, Lesotho, Zimbabwe, and Swaziland. The fruit is consumed traditionally as food in the northern coastal region of Kwazulu-Natal in South Africa and the Southern part of Zimbabwe. This study investigated the nutritional, anti-nutritional composition, and cytotoxicity of S. madagascariensis ripe fruit. Fruits were randomly selected, and the parameters of each experiment were measured in triplicates. The seed coat and fruit pulp were analysed for proximate, mineral and anti-nutrients (phytic and oxalic acid) composition using standard protocols. The cytotoxic effect of methanolic extracts from the fruit parts of S. madagascariensis was tested on human embryonic kidney (HEK293) and cervical cancer (HeLa) cell lines using the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide] cell proliferation assay. The fruit pulp’s moisture (6%), ash (11%), protein (5%), fat (1%), fibre (12%), and carbohydrate (12%) contents were significantly different (P<0.05) from the compositions of the fruit pulp (5% moisture, 5% ash, 4% protein, 33% fat, 8% fibre and 11% carbohydrate). The minerals analysed were significantly (P<0.05) higher in the fruit pulp compared to the seed coat (testa). The fruit's seed coat and fruit pulp's methanolic extracts did not show any significant toxicity in the HEK293 cell line. The seed coat's methanolic extract exhibited moderate toxicity in the HeLa cell line. The methanolic extracts from both fruit parts showed a dose-dependent effect in HEK293 and HeLa cell lines. The results of the cytotoxicity analysis revealed the safe nature of the fruit pulp while caution needs to be taken when consuming the seed coat. The seed coat contained 1.39±0.01% phytic acid, but oxalic acid and phytic acid were not detected in the fruit pulp. This study suggests that the fruit parts could serve as a source of potassium, magnesium, and nitrogen, but poor sources of protein, carbohydrates, and fat (pulp). Key words: Anti-nutrients, Cytotoxicity, Extracts, Fruit, Minerals, Proximate, Pulp, Seed
The subak-based agro-tourism management model in the world cultural heritage area of Catur Angga Batukaru Tabanan Regency, Bali province, Indonesia
Authors:   Udayana University, Suamba IK , Sumiyati Sumiyati , Krisnandika AAK , Tika IW , Sulastri NN , Arisena GMK
Published: February 2023

When it was designated as a World Cultural Heritage (WCH) in 2012, there were 14 Subak organizations formed in Catur Angga Batukaru Area. However, it seems that only Subak Jatiluwih has the privilege to experience rapid development as a tourism destination. The other 13 Subak area in Catur Angga Batukaru has not been well developed. The beauty of their rice terraces, plantation fields, temples and rivers has not been appropriately exposed to the tourists. Further studies are required to investigate the potencies of 13 Subak areas in the Catur Angga Batukaru Area as tourism destinations. An adequate management model would properly assess the potencies of these areas and simultaneously enhance the farmers' well-being, improve the tourist satisfaction level and conserve the environment. The existence of the 13 Subak in Catur Angga Batukaru and its potencies should have developed through the agro-ecotourism-based management model. Hence, this study aimed to organize a Subak-based agro-ecotourism management model in the WCH of Catur Angga Batukaru. The study’s primary data were collected from farmers’ respondents through a direct survey using a questionnaire prepared prior to the data collection. In-depth interviews were also conducted to gather the study data. This study applied qualitative and quantitative descriptive methods. Findings revealed that the rest of the areas required to be properly built in the WCH of Catur Angga Batukaru Area. These areas would provide spaces to enjoy the beauty of the Subak terraces and the local plantation fields. Hiking tourism in this area has been developed by the Subak organizations and local travel agents under the surveillance of the local tourism departments. Several tourism supporting facilities such as restaurants and home stays also should have been managed by Subak or local investors. It would help the tourism sites to directly contribute to the well-being of the local community, especially the members of Subak. The future management of agro-ecotourism is also required to involve all Subak organizations in the area. A proper management model not only helps Subak to present themselves as the main subject of a tourism program but also makes them capable to experience the advantageous impacts of the agro-ecotourism development. Key words: agro-ecotourism, Mount Batukaru, rice cultivation, sustainability, Subak, terrace, WCH
Testing a profit margin hedging model as a price risk-management solution for crop farmers in South Africa
Authors:   CropsProfit, Graupner DL , Graupner LI ,   North-West University
Published: February 2023

Risks inherent in the agricultural environment are often complex and include a combination of risks such as production risk (weather), market risk (uncertain prices), technological risks (new production techniques), price risk (changes in input and output prices) and institutional risk (changes in policies). Also, farmers experience personal and financial risks, which relate to cash flow and the ability of the business to generate sufficient profit. Literature shows that crop farmers manage price risk to fulfil the end-values of security, feeling good and operating a viable and competitive business. A profit margin hedging approach could effectively be used as a price risk management strategy. Although certain other agricultural industries are using profit margin hedging as a risk management strategy, not much is known of the usage and success of this strategy in crop farming. A gap in research exists where an effective plan combines the various components into an effective crop risk management strategy. It is also evident that a gap in practice exists where all the components identified in the literature are not combined into a working model to do better price risk management on a daily basis. Consequently, this study aimed to test the performance of such a new profit margin hedging (PMH) model, with and without using put options as a pre-harvest strategy, against the performance of a control group. The study was conducted in the Free State Province in South Africa. Data for eight (8) seasons of a group of ten farmers were obtained from a bureau service. The data was analysed using the software suite Jamovi 1.0.7.0. Independent t-tests were used to compare the profitability of the new PMH model to the control group. Statistically, significant differences were reported between the groups. The study found both a significant improvement in profitability and a stabilising effect on profitability when using a profit margin hedging approach. This study proposes that crop farmers can operate more viable and secure businesses by utilising a profit margin hedging model. Key words: agriculture marketing, crop farmers, price risk management, profit margin hedging
Pancreatic toxicity of influenza A/H1N1-California virus infection in mice at the background of hyperglycemia induced by streptozotocin administration
Authors: Molodykh O. P. , Palchikova N. A. , Selyatitskaya V. G. , Glushchenko A. V. , Kurskaya O. G.
Published: February 2023

Particular attention in the study of comorbid conditions is paid to viral diseases, in particular, those caused by the pandemic influenza virus type A subtype H1N1, as one of the most pathogenic and contagious. Investigation of the effect of this virus in the development of diabetes mellitus will make it possible to more effectively carry out preclinical studies to find the most effective methods of treating a viral infection against the background of a pre-existing somatic pathology. Purpose of the study was to evaluate the pancreatic toxicity effect of exposure to influenza A/H1N1-California virus in the development of streptozotocin diabetes in DBA/2 and BALB/c mice. Material and methods. Groups of mice DBA/2 (n = 36) and BALB/c (n = 58) were formed: infected with influenza A/H1N1-California virus (at different doses); with the introduction of a solution of streptozotocin at a dose of 150 mg / kg; with the combined use of agents. Life expectancy, blood glucose and insulin level, pathomorphological changes in the pancreas were assessed. Results and discussion. The death of animals was observed only in mice of the DBA/2 line: with the introduction of streptozotocin – 12.5 %, with intranasal infection with the virus (at a dose of 5.7 lg TCID50) – 80 %, with combined exposure – 78 %. A comparative study of mice of the DBA/2 and BALB/c lines showed the possibility of using mice of both lines to study the combined effect of influenza A/H1N1 virus and experimental diabetes, taking into account the dose of infection. Infection of BALB/c mice caused the formation of morphological changes only in the exocrine part of the pancreas. In mice of both lines, after the administration of streptozotocin, persistent hyperglycemia was formed, and pathomorphological changes in the pancreas were recorded mainly in the endocrine part. Similar changes in the pancreas, but more severe, involving the exocrine zone, were found during subsequent infection: in mice of the DBA/2 line in the form of a focal disorder of the acinar structure with degeneration of acinocytes and a compensatory regenerative reaction of cells in intact areas; in mice of the BALB/c line in the form of more significant damage to the ductal system than in DBA/2 with the formation of powerful periductal fibrosis and mononuclear infiltrates. Conclusions. A comparative study showed that DBA/2 mice had more pronounced changes in both the exocrine and endocrine apparatus of the pancreas when infected with influenza A/H1N1-California virus and experimental diabetes mellitus.
Algorithm for determining the authenticity of biomedical cell preparations containing mesenchymal stem cells
Authors: Druzhinina S. S. , Loginova M. A. , Smirnova D. N. , Obukhov I. P. , Yaroshenko K. O. , Poponina E. A. , Nazarova E. L. , Isaeva N. V. , Paramonov I. V.
Published: February 2023

The use of mesenchymal stem cells (MSCs), which have a pronounced immunomodulatory activity, is a promising direction in the development of biomedical cell preparations (BMCPs). In oncohematology, the use of BMCPs containing MSCs is aimed at supporting hematopoiesis during cotransplantation with hematopoietic stem cells (HSCs) and suppressing immune conflicts during allogeneic unrelated transplantation and severe autoimmune processes. An obligatory stage of registration of BMCPs is confirmation of the identity of the MSC cell line (CL), which includes the establishment of morphological characteristics, evaluation of the expression of specific markers and proteins, and confirmation of the genetic stability of CL during cultivation. Determination of markers of genetic stability is possible using various methods, however, according to the recommendations of the American National Standardization Institute, the standard is the analysis of short tandem repeats (STR analysis). The purpose of the study is to develop an algorithm for determining the authenticity of BMCPs containing MSCs, including STR analysis. Material and methods. Identification of MSC cells in BMCP was performed according to the criteria of the International Society for Cell Therapy. Viable cells were counted in a Goryaev chamber. Immunophenotypic characteristics of MSCs were determined by flow cytometry. The level of production of specific proteins was assessed using enzyme immunoassay. Genetic stability markers were identified by STR analysis. Results and discussion. The methods were tested in triplicate for ten BMCP samples to confirm the reproducibility and reliability of the results. The developed algorithm for determining the authenticity of BMCP has a high accuracy, as it includes the STR analysis technique, which makes it possible to identify 19 polymorphic STR markers located on different alleles. Using the method will allow BMCP manufacturers to go through the procedure of state registration of drugs.
Diastolic stress test in assessing functional state of postinfarction myocardium
Authors: Vorobev A. M. , Ruzov V. I.
Published: February 2023

Taking into account the conflicting literature data and the ambiguity in the interpretation of parameters of diastolic heart function in patients with coronary heart disease, we conducted an analysis of diastolic heart function in patients after myocardial infarction at the outpatient rehabilitation stage. Aim of the study was to investigate the diagnostic information content and the feasibility of diastolic stress testing to assess the functional condition of postinfarction myocardium. Material and methods. 86 patients were examined at the outpatient stage of rehabilitation 6 weeks after myocardial infarction with coronary artery stenting ad hoc. The control group consisted of 10 healthy volunteers. Structural and functional examination of the heart was performed at rest and immediately after exercise using stress echocardiography. Results and discussion. Patients after myocardial infarction have a larger indexed volume of the left atrium (30.71 ± 8.88 vs. 20.49 ± 4.04 ml/m2) and an E/e` ratio (8.45 ± 3.27 vs. 6.46 ± 1.42) in comparison with the control group. 38 (62.3 %) patients with normal left ventricular (LV) ejection fraction (EF) had unimpaired LV diastolic function, 19 (31.1 %) and 2 (3.3 %) patients had type 1 and type 2 diastolic dysfunction, respectively, 2 patients (3,3 %) had an indeterminate result. Patients with reduced LV EF have a significantly lower early diastolic mitral annular velocity (e`). The diastolic stress test revealed a significant post-exercise increase in E/e` in only one patient (from 8.92 to 18.37), who also had an initially reduced EF (32 %). The stress test showed no significant changes in diastolic heart parameters after exercise in patients suffering from heart failure with preserved EF, which may indicate relatively good diastolic reserves of the heart. Conclusions. Myocardial infarction is accompanied by the presence of LV diastolic dysfunction in 53,5 % of the patients at the 6th week of the rehabilitation period. The diastolic stress test is accompanied by a rare occurrence of stress-induced diastolic dysfunction (4 %) in patients with reduced LV EF after myocardial infarction.
Diverticular disease of the sigmoid colon, complicated by a tubular intestinal fistula of the anterior abdominal wall and cicatricial stricture of the sigmoid colon (case report)
Authors: Klimentov M. N. , Sysoev S. V. , Chupina M. S.
Published: February 2023

Aim of the study was to consider a clinical example of diverticular disease of the sigmoid colon, complicated by a tubular intestinal fistula of the anterior abdominal wall and cicatricial stricture of the sigmoid colon.Material and methods.Patient B., 76 years old, was admitted to the proctology department with complaints of the presence of a fistula with purulent discharge in the area of the surgical scar. Preoperative examination with MRI, colonoscopy, fistulography revealed diverticular disease of the sigmoid colon, complicated by a tubular intestinal fistula of the anterior abdominalwall and stricture of the sigmoid colon at the level of the internal opening of the fistula.Results.The operation was performed in the following volume - excision of the fistula, resection of the sigmoid colon bearing the fistula, with endto-end anastomosis in the area without diverticula.
Dynamika reaktywacji: uwie(r)żyć na słowo… grupie Twożywo?
Authors: Lachman Magdalena
Published: February 2023

Artykuł poddaje namysłowi aktywność grupy Twożywo, którą tworzą Mariusz Libel i Krzysztof Sidorek, działający w Polsce od połowy lat 90. XX wieku w obszarach street artu, net artu, grafiki użytkowej, designu i sztuki. Asumpt do podjęcia refleksji daje opublikowana w 2020 roku książka Plądrujemy ruiny rzeczywistości, pieczołowicie przygotowana pod względem koncepcji i kształtu typograficznego publikacja, którą zwykle uznaje się za retrospektywny katalog, postscriptum, podsumowanie czy monografię. Autorka polemizuje z tą tezą, wskazując, że lepiej rozpatrywać pozycję w charakterze artbooka, wypowiedzi artystycznej, której celem jest testowanie możliwo­ści, jakie w zakresie prezentacji i rearanżacji dla wcześniejszych realizacji Twożywa daje medium książkowe. Autorka weryfikuje ponadto różne informacje faktograficzne dotyczące grupy. Nieuf­nie podchodzi zwłaszcza do daty oficjalnego zakończenia działalności duetu. Formacja wprawdzie oficjalnie ogłosiła dezaktywację w 2011 roku, jednak trudno mówić o jej całkowitym zamilknięciu czy wygaszeniu obecności na scenie artystycznej w świetle podejmowanych przez twórców późniejszych aktywności, również tych ostatnich już po wydaniu książki Plądrujemy ruiny rzeczywistości, kiedy następuje przyrost ich kolejnych ciekawie zakrojonych dzieł.
Revisión del marco lógico: conceptualización, metodología, variaciones y aplicabilidad en la gerencia de proyectos y programas
Authors: Cárdenas Torrado Lenith , Cruz Casallas Nubia Estella , Álvarez Cardona Numar
Published: February 2023

La metodología del marco lógico es una herramienta ampliamente utilizada en los ámbitos nacional e internacional para desarrollar la planificación, el seguimiento y la evaluación de proyectos y programas. El objetivo de esta investigación se centra en la consulta y presentación de conceptos, origen, metodología, variaciones y aplicabilidad de la técnica; para lo cual fue necesario realizar una revisión bibliográfica, interpretación y análisis de textos con el método de análisis de contenido. A partir del ejercicio efectuado, se logró concluir la factibilidad de la metodología, las ventajas en comparación con otros métodos menos estructurados y la pertinencia del formato, ya que esto posibilita el establecimiento de objetivos, la determinación de los medios para lograr las metas planeadas, la definición de los mecanismos de verificación y la identificación de los riesgos que se pueden presentar en la ejecución del proyecto.
Códigos JEL: O22
Recibido: 25/10/2021. Aceptado: 22/02/2022. Publicado: 01/06/2022.
Pengaruh Teman Sebaya dan Peran Orang Tua Sebagai Prediktor Perilaku Seks Pranikah pada Remaja
Authors: Irma Irma , Yuni Yuni , Paridah Paridah
Published: February 2023

Masa remaja merupakan periode terjadinya pertumbuhan dan perkembangan baik secara fisik, psikologis maupun intelektual dengan berbagai keunikan dan rasa ingin tahu yang tinggi termasuk persoalan seks. Salah satu risiko yang diahadapi remaja dimas ini adalah perilaku seks pranikah yang berakibat buruk dan merugikan bagi remaja. Penelitian ini merupakan penelitian survei analitik dengan pendekatan Cross Sectional Study yang bertujuan untuk menganalisis pengaruh teman sebaya dan peran orang tua terhadap perilaku seks pranikah pada remaja. Populasi penelitian ini adalah seluruh remaja di Kecamatan Kepulauan Masaloka Raya sebanyak 265 orang dengan sampel sebanyak 174 orang yang diambil dengan teknik simple random sampling.  Hasil analisis antara variabel penentu dan variabel efek dengan uji chi square diperoleh teman sebaya dengan nilai p = 0,000 < 0,05 dan peran orang tua dengan nilai p = 0,079 > 0,05. Kesimpulan dari penelitian ini adalah pengaruh teman sebaya merupakan faktor prediktor terjadinya seks pranikah pada remaja sedangkan faktor peran orang tuan bukan merupakan faktor prediktor dari perilaku seks pranikah pada remaja.
Pengaruh Karakteristik Ibu Terhadap Status Imunisasi Dasar Pada Anak Usia 12-23 Bulan di Indonesia: Analisis Data Survei Demografi dan Kesehatan Indonesia 2017
Authors: Cholilah Cholilah , Afridah Wiwik
Published: February 2023

Imunisasi merupakan salah satu upaya preventif yang menjadi prioritas agar dapat mencegah kesakitan dan kematian anak. Namun, cakupan imunisasi yang belum mencapai target nasional membuktikan bahwa program pelaksanaan imunisasi belum berjalan dengan baik, dan penerimaan imunisasi pada anak berkaitan dengan lingkungan anak. Penelitian bertujuan untuk melihat pengaruh karakteristik ibu terhadap status imunisasi pada anak di Indonesia. Penelitian ini menggunakan jenis observasional analitik dengan desain cross-sectional. Jumlah populasi yaitu jumlah sampel 3.363 anak usia 12-23 bulan responden pada data SDKI 2017. Analisis data dalam penelitian ini menggunakan regresi logistik sederhana pada uji bivariat dan regresi logistik berganda pada uji multivariat. Hasil penelitian tentang cakupan imunisasi dasar lengkap pada anak sebesar 59,60%. Hasil analisis multivariat menunjukkan bahwa terdapat pengaruh yang signifikan secara statistik dari karakteristik usia (p=0,006; AOR=1,400; 95%CI=1,101-1,781), pendidikan (p<0,001; AOR=1,340; 95%CI=1,148-1,564), status ekonomi (p<0,001; AOR=1,402; 95%CI=1,196-1,645) dan jumlah anak (p<0,001; AOR=0,681; 95%CI=0,586-0,790) terhadap status imunisasi dasar lengkap.  Sedangkan pekerjaan ibu (p=0,513; AOR=0,954; 95%CI=0,827-1,100) tidak signifikan mempengaruhi status imunisasi Dasar lengkap. Perlu adanya edukasi dan promosi imunisasi yang dapat diakses secara gratis di Puskesmas, posyandu atau menggunakan BPJS kesehatan di beberapa tempat pelayanan kesehatan.
Hubungan Paritas Ibu Dengan Kejadian Plasenta Previa Di Indonesia: Systematic Literature Review
Authors: Sakinah Salsabilla Amalia , Sebayang Susy Katikana , Kurnia Dewi Desak Made Sintha
Published: February 2023

Perdarahan menempati peringkat pertama di Indonesia sebagai penyebab kematian ibu dengan persentase sebesar 28%. Perdarahan antepartum menjadi salah satu penyebab yang mengancam hidup ibu dan janin adalah plasenta previa. Penelitian ini dilakukan untuk mengkaji hubungan paritas dengan plasenta previa melalui berbagai literatur. Penelitian ini menggunakan metode systematic literature review dan rancang bangun case-control dengan database Google Scholar serta memiliki kriteria inklusi yaitu jurnal berbahasa Indonesia publikasi tahun 2017-2022. Berdasarkan hasil pencarian ditemukan empat literatur yang sesuai kriteria inklusi. Hasil analisis literatur tersebut diperoleh hasil bahwa tiga penelitian menunjukkan bahwa paritas menjadi salah satu faktor risiko kejadian plasenta previa khususnya di Indonesia. Namun terdapat satu penelitian pada populasi yang memiliki riwayat operasi sesar dan gemeli menunjukkan bahwa tidak adanya hubungan paritas ibu dengan kejadian plasenta previa. Berdasarkan hasil penelitian dapat disimpulkan bahwa terdapat hubungan antara paritas dengan kejadian plasenta previa. Maka dari itu, program KB masih perlu dilaksanakan dan perlu adanya pemeriksaan secara khusus kepada ibu dengan paritas lebih dari satu untuk mendiagnosis secara dini plasenta previa sehingga dapat dilakukan penanganan yang tepat untuk mencegah kematian ibu akibat plasenta previa.
ANXIETY LEVEL OF MIDWIFERY CLINICAL STUDENTS DURING COVID-19 PANDEMIC
Authors: Syafira Nadia Sherli , Miftahussurur Muhammad , Frety Endyka Erye
Published: February 2023

Introduction: Clinical midwifery students experience higher anxiety than the general population during COVID-19 pandemic. The higher level of anxiety is due to pressure in their clinical learning environment. This study will explore the effect of the clinical learning environment on the increased anxiety in midwifery students during the COVID-19 pandemic. Method: This prospective cross-sectional study was conducted on 82 clinical midwifery students at Airlangga University using an online survey. We excluded students who had not started clinical studies and students with pre-existing medical or comorbid psychiatric conditions that could explain the pain. Information from participants included  socio-demographic, clinical learning environment questionnaire, and Hamilton Rating Scale for Anxiety (HRS-A). Results: The study showed that most of the respondents aged 20-27 years (73.2%), in the second semester (76.8%), living in boarding houses/contracts (74.4%), unmarried status (75.6%), the level of family income is very high (68.3%), and the perception of a poor clinical learning environment (51.2%). Participants experienced no anxiety the most (52.4%) and significantly correlated with the age p=0.047, domicile status p=0.076, and clinical learning environment p=0.008. But not their semester p=0.991, marital status p = 0.406, and family income p=0.872. Conclusion: These data indicate that age, domicile status, and clinical learning environment contribute to the incidence of anxiety in midwifery clinic students during the COVID-19 pandemic.
ANALYSIS ATTITUDE BRIDES AND GROOMS TO BE TOWARD PREMARITAL HIV TESTING
Authors: Visky Afrina  , Prasetyo Budi , Dewanti Linda
Published: February 2023

Background: In Surabaya, every bride and groom to be is required to do a premarital HIV testing, to knows their HIV status is positive or negative. In 2018, there were 127 HIV positive cases in bride and groom to be, but only 7.8% canceled marriage while 40.9% continued marriage, even 51.3% had unknown information. This study aims to analyze the attitude and knowledge of the bride and groom regarding premarital HIV testing. Method: this research was conducted at the Putat Jaya Health Center in Surabaya in July 2020 – January 2021, this type of research was a quantitative analytic design with a cross sectional research design. The number of samples was 72 prospective brides consisting of 36 prospective brides and 36 prospective grooms. The sampling technique used purposive sampling. The variables used were the attitude and knowledge of the bride and groom about premarital HIV testing. The instrument used was a questionnaire that had previously been tested for validity by the researcher. Data analysis used the chi-square test and fisher's exact test. Results: Overall the bride and groom who have good knowledge will tell their partner about the results of the HIV positive test they got, besides that 42.3% of the brides who are less knowledgeable are not willing to carry out routine consultations and treatment, but a small proportion are also found (18.8 %) of prospective brides and grooms who have good knowledge but  not willing to carry out routine consultations and treatment if they get HIV positive Conclusion: in general, the knowledge of the prospective bride and groom about HIV will influence the prospective bride and groom in their attitude, being willing to tell their HIV positive results to their partners or being willing to carry out continuity care for treatment, but not always good knowledge will give the prospective bride a positive attitude , so this needs more handling from health workers, especially in communication and education.
 
Key words: attitudes, knowledge , premarital HIV testing
RELATION TIMELINESS COMPLEMENTARY FEEDING WITH NUTRITIONAL STATUS OF INFANTS AGED 6-12 MONTH
Authors: Widowati Retnosari , Atika  , Husada Dominicus
Published: February 2023

Background: Infants aged six months and over have increased nutritional needs so that breast milk is no longer fulfilled because it is necessary to provide complementary foods for breast milk (MP-ASI) to reduce and prevent malnutrition. The provision of MP-ASI has a relationship with nutritional status. This study aims to know about the relationship between timeliness of complementary foods with the nutritional status of infants aged 6-12 months in the working area of ​​the Margorejo Health Center. Methods: The research design used an observational cross sectional. The population in this study were all mothers who had babies aged 6-12 months in the working area of ​​the Margorejo Health Center. Sampling technique using total sampling and the sample size was 64 respondents. Data were collected using a questionnaire. The research variables were timeliness, frequency, quantity, diversity of species and suitability of MP-ASI texture. Data analysis using contingency coefficient test to determine the correlation between the independent variable and the dependent variable. Results: Timeliness of complementary foods was shown by 53,13% respondents while 46,87% of them not on time in timeliness of complementary foods. The results showed that no relationship between the timeliness of complementary feeding with nutritional status with p value=0,64. Conclusion: This study shows that there is no relationship between the timeliness of complementary feeding with the nutritional status of infants.
 
Keywords: complementary feeding, timeliness, frequency, quantity, types of diversity, texture suitability, nutritional status
RISK FACTOR OF EXLUSIVE BREASTFEEDING AND INFECTIVE DISEASES ON STUNTING INCINDANCE
Authors: Nurlita sari Erma , Dewanti Linda , Fatmaningrum Widati
Published: February 2023

Background: Stunting one of the nutritional problems in the children under five wich has an impact on the distruption of children’s growth. The long-term impact will reduce the quality of Indonesian children in the future. Stunting is closed to first 1000 days of life. Many factos influence. Methode: The research method used in this research is observational analytic with case control approach. The sample was using simple random sampling. The number of sampels in the study were the age 6-36 month. 45 as cases and 45tooddler as control. The dependen variable in this study was stunting and the variable was history of exclusive breastfeeding, age of first complementary feeding, incidence of diarrhea and acut respiration disesase  infection (ARI),. Collecting data through primary and secondary data. Statistis test by chi square, t-test Independen and regresi logistic Result: The result showed history of exclusive breastfeeding test a value of p=0,010, incidence of diarrhea with a value of p=0,017 and history of ARI disease with a value of p=0,017, it shows that there is a relationship between the incidence of stuntingnin children age 6-36 month. The multivariate analys with logistic regression test result showed that there was the most relationtship with stunting are between a history of exclusive breastfeeding with OR=0.042 history of diarrhea incidence with OR=0.042, history of ARI disease with OR=6.627 and
Conclusions: The data on the result of the study showed that a history of exclusive breastfeeding, incidence of diarrhea, history of ARI disease has a significant relation with stunting..
 
keyword :  stunting, exclusive breastfeeding, history of child infection.