bluuebunny/crossref_metadata_2025 huggingface dataset:
Intravitreal aflibercept following treat and extend protocol versus fixed protocol for treatment of neovascular age-related macular degeneration
Authors: Abdin Alaa Din , Mohamed Asem , Munteanu Cristian , Weinstein Isabel , Langenbucher Achim , Seitz Berthold , Suffo Shady
Published: December 2021

Background

To assess the morphological and functional outcome of intravitreal aflibercept following the treat and extend protocol compared to the fixed protocol for treatment of eyes with neovascular age-related macular degeneration.

Methods

This retrospective study included 126 eyes of 113 patients with primary onset neovascular age-related macular degeneration who were followed for 12 months. All eyes were treated with 2 mg/0.05 mL aflibercept. All eyes received an upload with three monthly aflibercept injections. We subsequently studied two groups of eyes. For group 1, 54 eyes were treated following the treat and extend protocol. For group 2, 72 eyes were treated following the fixed protocol (fixed 2-monthly interval). Main outcome measures included: best corrected visual acuity (BCVA), central macular thickness (CMT) and number of injections.

Results

BCVA (logMAR) in group 1 vs group 2 was (0.61 ± 0.3 vs 0.72 ± 0.3, p = 0.09) before treatment and (0.48 ± 0.3 vs 0.51 ± 0.3, p = 0.6) after one year of treatment. CMT in group 1 vs group 2 was (371 ± 101 μm vs 393 ± 116 μm, p = 0.5) before treatment and (284 ± 60 μm vs 290 ± 67 μm, p = 0.1) after one year of treatment. Number of injections/eye in group 1 vs group 2 was (8.5 ± 2.2 vs 7.0 ± 0, p < 0.001).

Conclusions

Significant differences regarding BCVA and central macular thickness were not found between both treatment protocols during the first year of treatment using aflibercept. However, a significantly higher number of injections was needed for eyes in the treat and extend group during the first year of treatment. This might suggest that aflibercept should better not be extended past an 8 weeks interval during the first year of treatment.

Study registration

This study was approved by the Ethics Committee of the Medical Association of Saarland, Germany (Nr. 123/20, Date: 16.06.2020). All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.
Evaluation of microbial contamination on cuff syringe, cuff pressure gauge, and their surroundings in the operating room
Authors: Oishi Rieko , Nakamura Kiwamu , Yahagi Yoko , Ohashi Kazutaka , Takano Yukiko , Harada Rie , Obara Shinju , Inoue Satoki , Kanemitsu Keiji , Murakawa Masahiro
Published: December 2021

Background

Some institutions reuse cuff syringes and do not periodically sterilize cuff pressure gauges. Pathogenic bacterial contamination of such equipment may increase the probability of pathogen transmission to patients during anesthetic procedures. Therefore, microbial contamination on cuff syringes, cuff pressure gauges, and their surroundings was assessed in the operating rooms of a university-affiliated tertiary care hospital in Japan.

Methods

This study was conducted between April and May 2019 in 14 operating suites at a hospital. The following sites in each operating suite were sampled: cuff syringe (inner/outer components), outer components of cuff pressure gauge, cuff syringe and cuff pressure gauge storage drawers, and computer mice. The swabs were directly streaked onto agar plates and incubated. Then, the bacterial species were identified using mass spectrometry.

Results

The highest bacterial isolation was observed in computer mice, followed by the outside of cuff pressure gauges and the drawers of cuff pressure gauges (92.9, 78.6, and 64.3%, respectively). Most of the identified bacteria belonged to the Bacillus species, with colonization rates of 85.7, 57.1, and 57.1% on computer mice, cuff pressure gauges, and cuff pressure gauge storage drawers, respectively. Coagulase-negative Staphylococcus was found in 35.7% of the specimens and was more prevalent on computer mice (71.4%), followed by on cuff pressure gauges (64.3%).

Conclusion

Anesthesiologists should be aware of the possible pathogen contamination risk from cuff syringes, cuff pressure gauges, or associated equipment and take appropriate infection control measures to minimize the risk of pathogenic transmission.
Advances in liver US, CT, and MRI: moving toward the future
Authors: Vernuccio Federica , Cannella Roberto , Bartolotta Tommaso Vincenzo , Galia Massimo , Tang An , Brancatelli Giuseppe
Published: December 2021

Over the past two decades, the epidemiology of chronic liver disease has changed with an increase in the prevalence of nonalcoholic fatty liver disease in parallel to the advent of curative treatments for hepatitis C. Recent developments provided new tools for diagnosis and monitoring of liver diseases based on ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI), as applied for assessing steatosis, fibrosis, and focal lesions. This narrative review aims to discuss the emerging approaches for qualitative and quantitative liver imaging, focusing on those expected to become adopted in clinical practice in the next 5 to 10 years. While radiomics is an emerging tool for many of these applications, dedicated techniques have been investigated for US (controlled attenuation parameter, backscatter coefficient, elastography methods such as point shear wave elastography [pSWE] and transient elastography [TE], novel Doppler techniques, and three-dimensional contrast-enhanced ultrasound [3D-CEUS]), CT (dual-energy, spectral photon counting, extracellular volume fraction, perfusion, and surface nodularity), and MRI (proton density fat fraction [PDFF], elastography [MRE], contrast enhancement index, relative enhancement, T1 mapping on the hepatobiliary phase, perfusion). Concurrently, the advent of abbreviated MRI protocols will help fulfill an increasing number of examination requests in an era of healthcare resource constraints.
Exploring meal frequency and vegetable intake among immigrants 70 years or older in Sweden
Authors: Johannesson Julie , Gustafsson Susanne , Slinde Frode , Rothenberg Elisabet
Published: December 2021

Background

Earlier research regarding immigrants has shown that lifestyle and environmental factors are of importance for the risk of developing certain diseases. Food habits are one of these factors. As there is little research concerning immigrants and food habits, the aim of the present paper was to explore food habits operationalised as meal frequency and vegetable intake among a group of older immigrants in Sweden. Specifically, the following questions were explored: changes in food habits when migrating, missing food from the native country, gender differences in food habits and association between food habits and self-rated health and well-being.

Method

A total of 131 persons from the health-promoting study “Promoting Aging Migrants’ Capabilities” (PAMC) conducted in Gothenburg, Sweden, 2011–2014, were included in this exploratory secondary analysis of questionnaire data. Participants were 70 years or older, cognitively intact, and living in ordinary housing. They had all migrated to Sweden from Finland or the Western Balkan Region (Bosnia-Herzegovina, Croatia, Montenegro and Serbia). Descriptive statistics as well as binary logistic regression were used to answer the research questions.

Results

Forty-eight percent of the participants in PAMC reported that they had changed their food habits when migrating, and 17% considered that they missed certain foods from their native country. Most of the participants migrated to Sweden more than 20 years ago. There was a significant difference in self-rated health in favour of the male participants (p = 0.02), but food habits, operationalised as meal frequency and vegetable intake, were not associated with self-rated health or life satisfaction.

Conclusion

Men rated their health as better than women did, but food habits operationalised as meal frequency or vegetable intake, were not associated with self-rated health or life satisfaction. Results from this secondary analysis were affected by methodological shortcomings. Further studies to understand the role of food habits in relation to health in a migration context are desired.

Trial registration: NCT01841853, Registered April 29, 2013. Retrospectively registered.
Cardiac hydatid cyst presenting as ventricular arrhythmia: a case report
Authors: Ameen Abdullah , Hilal Kiran , Shaikh Asra , Khan Faheemullah , Fatimi Saulat
Published: December 2021

Background

Hydatid disease caused by Echinococcus granulosus commonly involves the liver followed by lungs. Cardiac involvement is a rare occurrence and presents a challenging scenario.

Case presentation

Our case describes a middle-aged gentleman who presented to the emergency room with an episode of sudden loss of consciousness resulting from ventricular tachycardia. After successful cardiac resuscitation, the patient underwent imaging that showed a lesion compatible with hydatid cyst. Surgical treatment with pharmacologic coverage was provided which resulted in good clinical outcome.

Conclusions

The case highlights rare occurrence of isolated cardiac hydatid disease presenting as cardiac arrhythmia in contrast to its common routine outpatient presentation involving the liver and lungs. Good knowledge of the unusual presentations and its epidemiology is essential to the proper management of such patients.
Could potentially calprotectin be a promising biomarker to oracle biologic therapy response in rheumatoid arthritis?
Authors: El-Kady Rania Abd El-Hamid , Fathy Ayah , Othman Talaat , Hafez Eman
Published: December 2021

Background

The advent of novel biologic agents for the treatment of rheumatoid arthritis (RA) has proven to be highly productive. Nonetheless, high cost, side effects, and unresponsiveness to these agents dictates the assignment of biomarkers that can foretell treatment response. Currently, calprotectin (a member of the S100 protein family) is amongst the enormously studied candidates in this perspective. Yet, conflicting results have been published. The main purpose of this study was to explore the role of serum concentration of calprotectin to predict the response to biological therapy in RA patients, so as to customize RA treatment.

Results

Baseline serum calprotectin levels were significantly higher in RA patients compared to the control subjects (Pvalue < 0.001). After receiving biologic therapy, a remarkable reduction (P< 0.001) in serum calprotectin was noted in RA cohort. Moreover, no correlation was found between the 28 joint count disease activity score (DAS28) and serum calprotectin levels neither before or after biologics. Intriguingly, no statistically significant association was detected between circulating calprotectin level and response to biological therapy.

Conclusion

Serum calprotectin concentrations could not be used as a biomarker to forecast clinical response to biological therapy in RA patients. However, further studies involving larger cohort of RA patients should be carried out to deliver more insight in this regard.
A novel differential diagnosis for diffuse cavitating nodules: primary pulmonary plasmacytoma
Authors: Panduranga Shruthi , Kade Samson , Shivakumar Swarna , V Harisha , Mehta Ravindra M.
Published: December 2021

Background

Extramedullary plasmacytoma is a rare monoclonal plasma cell neoplasm that originates from tissues other than the bone marrow and constitutes only 3%–5% of all plasma cell neoplasms. Most cases involve the upper respiratory tract. Extramedullary plasmacytoma involving the lung is extremely rare. Primary pulmonary plasmacytoma is a rare type of extramedullary plasmacytoma, usually presenting with a nodule or mass in hilar region. Literature search has shown very few cases of immunohistochemically confirmed cases of pulmonary plasmacytoma. Diffuse pulmonary infiltration is an unusual presentation.

Case presentation

We report the case of a 56 year old lady with history of cough and breathlessness since one month. Computed Tomography revealed diffusely scattered multiple cavitating nodules and consolidation in both lungs. Computed Tomography guided biopsy of one of the lung nodules was done. Histopathologic examination and immunohistochemistry showed features of pulmonary plasmacytoma .This is an unique case of primary pulmonary plasmacytoma with the rare presentation as diffusely scattered multiple cavitating nodules and consolidation. According to our literature search, primary pulmonary plasmacytoma manifesting as cavitating nodules is being reported for the first time.

Conclusions

Primary pulmonary plasmacytoma should be also be considered in the differential diagnosis of multiple diffusely scattered cavitating lung nodules.
Effect of standardized post-coercion review on subjective coercion: Results of a randomized-controlled trial
Authors: Wullschleger A. , Vandamme A. , Mielau J. , Stoll L. , Heinz A. , Bermpohl F. , Bechdolf A. , Stelzig M. , Hardt O. , Hauth I. , Holthoff-Detto V. , Mahler L. , Montag C.
Published: December 2021

Background

Post-coercion review has been increasingly regarded as a useful intervention in psychiatric inpatient setting. However, little is known about its effect on perceived coercion.

Methods

A multicenter, two-armed, randomized controlled trial was conducted, aiming at analyzing the effect of post-coercion review on perceived coercion. People with severe mental disorders, who experienced at least one coercive measure during inpatient treatment, were randomized using Zelen’s design to an intervention group receiving standardized post-coercion review, or a control group treated as usual. The MacArthur admission experience scale (AES) and the coercion ladder (CL) were used to assess perceived coercion during inpatient treatment. The coercion experience scale (CES) measured experienced coercion during the coercive intervention. Analyses of covariance were performed to determine group differences.

Results

Of 422 randomized participants, n = 109 consented to participate in the trial. A restricted intention-to-treat analysis of all individuals who consented revealed no significant effect of the intervention on perceived coercion. A significant interaction effect between the factors gender and intervention on the AES scores was found. Sensitivity analysis revealed significant effects of the intervention on both AES and CL scores and an interaction effect between intervention and gender, indicating a higher efficacy in women. No effect of the intervention on CES scores was found.

Conclusions

Standardized post-coercion review sessions did not alleviate the subjective perception of coercion in the total sample. However, post hoc analysis revealed a significant effect of the intervention in women. Results indicate the need to further address gender-specific issues related to coercion.
Οι οχυρώσεις ενός στρατηγικού Περάσματος
Authors: Καράμπελας Νίκος Δ.
Published: December 2021

Το στόμιο του Αμβρακικού κόλπου σχηματίζει έναν οφιοειδή πορθμό μήκους 12 περίπου χιλιομέτρων, το πλάτος του οποίου κυμαίνεται από 600 μέτρα μέχρι 4.500 μέτρα. Το στενότερο σημείο του πορθμού αυτού χρησιμοποιήθηκε, όπως ήταν φυσικό και λογικό, από τον άνθρωπο ως τόπος διαπεραίωσης από τη μια ακτή στην άλλη˙ ως πέρασμα, πέραμα. Το πέραμα αυτό πήρε αυτονόητα το όνομα της χρήσης του, του περάσματος δηλαδή, στη γλώσσα που ήταν κοινή στην περιοχή την εποχή που ονοματίστηκε, τουτέστιν Πρέβεζα, το οποίο στα αρβανίτικα σημαίνει πέρασμα.Αλλαγή στον οικιστικό χάρτη της περιοχής επέφερε η οχύρωσή της ‒λίγα χρόνια μετά την κατάκτηση της περιοχής από τους Οθωμανούς, το 1463‒ με την κατασκευή, το 1478, ισχυρού κάστρου στην είσοδο του κόλπου, στη Μπούκα του κόλπου, ala bucca delo gulfo κατά του Βενετσιάνους, στο Πέρασμα, στην Πρέβεζα κατά τους Αρβανίτες.Στα άρθρο αναφέρονται έντεκα τουλάχιστον κάστρα/οχυρά που κατασκευάστηκαν μέσα σε τέσσερις αιώνες, από τα τέλη του 15ου μέχρι το τέλος του 19ου αιώνα, στην περιοχή της Πρέβεζας.
Προσωπογραφία του Franz Xaver von Predl
Authors: Δόνος Δημοσθένης Αρ.
Published: December 2021

Στις 6 Φεβρουαρίου 1833 ο Όθων φθάνει στο Ναύπλιο, την τότε πρωτεύουσα του νεοσύστατου ελληνικού κράτους, συνοδευόμενος από το βαυαρικό επικουρικό στρατιωτικό σώμα το οποίο κατά τα έτη 1833-1835 πραγματοποίησε πολλές αποστολές ανά την τότε ελληνική επικράτεια. Ο αριστοκρατικής καταγωγής Franz Xaver von Predl, ο οποίος υπηρέτησε στο σώμα ως αξιωματικός, μετά την επιστροφή του στη Βαυαρία δημοσίευσε τα ενθυμήματά του από την Ελλάδα.Το παρόν άρθρο παρουσιάζει για πρώτη φορά μια σχολιασμένη μετάφραση και ιστορική ανάλυση των κεφαλαίων που αφιερώνονται στη χρονική περίοδο κατά την οποία ο v. Predl βρισκόταν με το τάγμα του στη Βόνιτσα και επισκέφτηκε στην αντίπερα όχθη του Αμβρακικού κόλπου –ο οποίος τότε αποτελούσε τη συνοριακή γραμμή μεταξύ των δύο επικρατειών– την τελούσα υπό οθωμανική κυριαρχία Πρέβεζα, όπως και την αρχαία Νικόπολη.Επιπλέον, η αφήγηση του Predl αντιπαραβάλλεται με τις εντυπώσεις περιηγητών που επισκέφθηκαν την περιοχή κατά την ίδια περίπου περίοδο αλλά και με όσα καταγράφονται στα γνωστά, αλλά μεταγενεστέρως εκδοθέντα ενθυμήματα του Χριστόφορου Νέεζερ, ο οποίος υπηρέτησε επίσης στην ίδια περιοχή ως αξιωματικός του επικουρικού σώματος. Τοιουτοτρόπως, αποκομίζει κανείς μια εξαιρετικά εναργή ιστορική και κοινωνική εικόνα αυτού του μεθοριακού χώρου.Αbstractn the 6th February 1833, Otto of Bavaria, the elected king of Greece,arrived at Nauplion, then capital of the newborn kingdom of Greece,accompanied by a Bavarian auxiliary corps that between 1833 and 1835 undertookvarious missions to many regions of the Greek state. Franz Xavervon Predl, a Bavarian aristocrat, served at this corps as first lieutenant, andimmediately after his return to Germany published a book about his Greekadventure. This article provides for the first time an annotated translation andhistorical analysis of the chapters concerning Predl’s stay with the army atthe town of Vonizza as well as his visits in the Ottoman town of Preveza andthe nearby ancient Nicopolis, all located in the region of Ambracian Gulf,then a borderline zone between Greece and the Ottoman Empire.
Πρέβεζα 1897: Μια φορά και ένα … νταλιάνι στη διάρκεια του Ελληνοτουρκικού πολέμου
Authors: Χαιρέτη Φωτεινή Νικόλαος
Published: December 2021

Τα γεγονότα που περιγράφονται στις επόμενες σελίδες αναδεικνύουνμια πραγματικότητα του δεδομένου ιστορικού τόπου και χρόνου, ηοποία μέχρι σήμερα παρέμενε άγνωστη ή, εν πάση περιπτώσει, ελά-χιστα γνωστή. Η πρωτογενής αρχειακή πηγή που χρησιμοποιήθηκε για τηνπαρούσα εργασία είναι ένα κατάστιχο πρακτικών του οθωμανικού Πρωτο-βάθμιου Δικαστηρίου Πρέβεζας (Preveze Bidayet Mahkemesi). Το κατάστιχοαυτό φυλάσσεται στη Βιβλιοθήκη του Πανεπιστημίου Ιωαννίνων.1 Είναιγραμμένο στα οθωμανικά, σε γραφή rık’a, και περιλαμβάνει συνολικά δεκα-εννιά υποθέσεις που χρονολογούνται τα έτη 1896-1898. Από τις υποθέσειςαυτές οι περισσότερες (δώδεκα) είναι αντιδικίες μεταξύ χριστιανών· έξι υπο-θέσεις αφορούν αντιδικίες μικτές, δηλαδή μεταξύ ενός χριστιανού και ενόςμουσουλμάνου και μόλις μία είναι αποκλειστικά μεταξύ δύο μουσουλμάνων.
Επισκέπτες, εκδηλώσεις και γιορτές της Παιδόπολης Ζηρού το 1948
Authors: Αγάθος Στέφανος
Published: December 2021

Λαμβάνοντας υπόψη το γεγονός ότι η επιστήμη της Ιστορίαςεξετάζει όλες τις πτυχές μιας πολεμικής αναμέτρησης κι όχι μόνο τις πιογνωστές στο ευρύ κοινό, θα πρέπει να επισημανθεί πως ο Ελληνικός Εμφύ-λιος έχει κι άλλες συνιστώσες λιγότερο γνωστές ή αλλιώς παραλειπόμενες.Μία από αυτές είναι και η εκκένωση των βόρειων παραμεθόριων περιοχώντης χώρας, ήδη από το 1947, ώστε ο άμαχος κυρίως πληθυσμός των περιο-χών αυτών να μετακινηθεί σε χώρους ελεγχόμενους από την επίσημη κυβέρ-νηση. Στο πλαίσιο αυτό εντάσσεται και η μεταγωγή των παιδιών στις Παι-δοπόλεις της βασίλισσας Φρειδερίκης, ένα ιστορικό ζήτημα, για το οποίοακόμα και σήμερα δεν είναι πολλές οι μελέτες που έχουν δημοσιευτεί στηνεπιστημονική κοινότητα, παρά τις κοινωνικές και πολιτικές προεκτάσεις του
Η απελευθέρωση της Πρέβεζας το 1912.
Authors: Αναστασόπουλος Νικόλαος Α.
Published: December 2021

Όψεις, καταγραφή και μαρτυρίες μέσα από το περιοδικό "Πρεβεζάνικα Χρονικά"
Το αποσιωπημένο χρονικό ενός ναυαγίου στην Πρέβεζα. Ναρκαλιευτικό Πηνειός, 24-10-1945
Authors: Κατηνιώτης Δημήτρης
Published: December 2021

Ο σκοπός εκπόνησης της μελέτης είναι η εξέταση των συνθηκών που οδήγησαν στην αιφνίδια απώλεια ενός πολεμικού πλοίου, σχεδόν αύτανδρου και μάλιστα σε θεωρητικά ειρηνική περίοδο. Διεξάγεται σαν μια προσπάθεια να διατυπωθεί εκ νέου η ιστορία του τραγικού ναυαγίου, δίνοντας ίσως το δικαίωμα λόγου σε αυτούς που ήταν πραγματικά παρόντες και γνώριζαν τι συνέβη, αλλά δεν μπόρεσαν ποτέ να το εκφράσουν.
Η νοσηλευτική κίνηση του νοσοκομείου Πρέβεζας κατά τα έτη 1937-1944
Authors: Αθανασοπούλου Ιωάννα
Published: December 2021

Στην παρούσα μελέτη έγινε προσπάθεια χαρτογράφησης της νοσολογικής κατάστασης της περιοχής της Πρέβεζας μέσα από το βιβλίο κινήσεως των ασθενών κατά τα έτη 1937-1944,2 λίγο πριν τον Β΄ Παγκόσμιο πόλεμο και κατά τη διάρκειά του. Συνολικά, οι ασθενείς που νοσηλεύτηκαν στο νοσοκομείο της Πρέβεζας κατά τα προαναφερθέντα έτη αανέρχονται σε 1.460 άτομα.
Στο σπίτι της ανέπνεε η άλλη Πρέβεζα
Authors: Νιάρχος Θανάσης
Published: December 2021

Βιβλιοκριτκή για το βιβλίο του πρεβεζάνου συγγραφέα  Σπύρου Μπρίκου, "Αγία Παπαλίνα η καλλονή"
Hercules Sapiens. Ο στωικός σοφός στις τραγωδίες του Seneca
Authors: Ντρίκος Σπύρος
Published: December 2021

Δεν αναφέρεται περίληψη
Λόγος και εικόνα στην εξέλιξη της τέχνης των εικονογραφημάτων
Authors: Παπαδημητρίου Απόστολος Σπ.
Published: December 2021

Στην παρούσα εργασία γίνεται προσπάθεια, ανάμεσα στα άλλα, να αποδει-χθεί ότι η τέχνη των εικονογραφημάτων ακολουθεί τη μεθοδολογία και τητεχνική η οποία είχε κατακτηθεί σε όλες τις παλαιότερες και σύγχρονες μορ-φές τέχνης. Στο πλαίσιο αυτό χρησιμοποιούνται παραδείγματα τέχνης από τααπώτατα χρόνια δημιουργίας του ανθρώπου έτσι ώστε να συμπεριληφθούνπαραδείγματα σχεδόν απ’ όλη την επικράτεια με ιστορικούς σταθμούς τηνΠαλαιολιθική και Προϊστορική εποχή, την κινέζικη τέχνη, τη μεσοποτάμια,την αιγυπτιακή. Δίνεται μεγαλύτερη έμφαση στην αρχαία ελληνική τέχνη και τη βυζαντινή και μεταβυζαντινή και στις ποικίλες μορφές που αναπτύχθηκαν. Τέλος, εντελώς αντιπροσωπευτικά παραδείγματα αναφέρονται και από έργα της σύγχρονης τέχνης ελληνικής και ξένης. Ως συμπέρασμα, αναδεικνύοντας τη μεθοδολογία και τεχνική δημιουργίας, τα εικονογραφήματα θεωρούμε ότι είναι τέχνη αυτόνομη και όχι δευτερεύουσα και παραπληρωματική των άλλων μορφών τέχνης. Επίσης, παρουσιάζονται τα κυρίαρχα χαρακτηριστικά που την καθιστούν τέχνη σημαντική που έχει τον δικό της χώρο ανάπτυξης
Δύο όψεις; πρόσθετο βάρος; Καντήλι;
Authors: Μπότσιος Βασίλειος
Published: December 2021

Ποιήματα
Ο Ηλίας Β. Βασιλάς και η πρεβεζάνικη πολεογραφία του. Μία ανάγνωση των Απάντων του
Authors: Ρέντζος Γιάννης
Published: December 2021

Δεν αναφέρεται περίληψη
Έκθεση για την αμυντική κατάσταση της Πρέβεζας πριν την απελευθέρωση του 1912
Authors: Σκλαβενίτης Σπύρος , Καράμπελας Νίκος Δ.
Published: December 2021

Η συλλογή πληροφοριών πριν ή κατά τη διάρκεια των πολεμικών συγκρούσεων αποτελεί κρίσιμο και ζωτικής σημασίας στάδιο της στρατιωτικής προετοιμασίας και μπορεί να αποδειχτεί καθοριστικός παράγοντας για την τελική έκβαση μιας επιχείρησης. Η διαδικασία αυτή ακολουθήθηκε και πριν τη μάχη της Νικοπόλεως που οδήγησε στην απελευθέρωση της Πρέβεζας, όπως προκύπτει από την εξέταση της σχετικής στρατιωτικής αναφοράς του Π. Σπηλιάδη
Σύμμικτη Πρέβεζα: Άπαντα Ηλία Βασιλά
Authors: Κόμης Κώστας
Published: December 2021

Βιβλιοκριτική για το βιβλίο "Άπαντα" του Ηλία Βασιλά
Etienne Labranche και Κωνσταντίνος Α. Βλαστός Δύο πολεμικοί ανταποκριτές της Le Temps στην Πρέβεζα του 1912-13
Authors: Καράμπελας Νίκος Δ.
Published: December 2021

Φωτογραφικό ντοκουμέντοο για την Πρέβεζα από του πολεμικούς ανταποκριοτές Etienne Labranche και Κωνσταντίνος Α. Βλαστός  της Le Temps στην Πρέβεζα του 1912-13
Αξιοβίωτη διαχείριση λιμναίων υδατικών συστημάτων: Η περίπτωση της λίμνης Ζηρού
Authors: Γιαννούλης Νικόλαος Δ.
Published: December 2021

Η λίμνη Ζηρού έχει ιδιαίτερο ενδιαφέρον, είναι ένα σημαντικό αξιοθέατο,αποτελεί ακόμη ένα αξιόλογο υδάτινο οικοσύστημα της χώρας και μια απότις βαθύτερες φυσικές λίμνες του ελλαδικού χώρου. Διαθέτει ιδιαίτερο φυσι-κό κάλλος και πλούσια και ποικίλη χλωρίδα και πανίδα. Το φυσικό περιβάλ-λον της λίμνης είναι ιδιαίτερα αξιόλογο τόσο από οικολογική άποψη όσο καιαπό την άποψη του τοπίου και της αισθητικής
Enhancement of pyocyanin production by subinhibitory concentration of royal jelly in Pseudomonas aeruginosa
Authors: Amly Dina Auliya , Hajardhini Puspita , Jonarta Alma Linggar , Yulianto Heribertus Dedy Kusuma , Susilowati Heni
Published: December 2021

Background: Pseudomonas aeruginosa, a multidrug-resistant Gram-negative bacterium, produces pyocyanin, a virulence factor associated with antibiotic tolerance. High concentrations of royal jelly have an antibacterial effect, which may potentially overcome antibacterial resistance. However, in some cases, antibiotic tolerance can occur due to prolonged stress of low-dose antibacterial agents. This study aimed to investigate the effect of subinhibitory concentrations of royal jelly on bacterial growth, pyocyanin production, and biofilm formation of P. aeruginosa.

Methods: Pseudomonas aeruginosa ATCC 10145 and clinical isolates were cultured in a royal jelly-containing medium to test the antibacterial activity. Pyocyanin production was observed by measuring the absorbance at 690 nm after 36 h culture and determined using extinction coefficient 4310 M-1 cm-1. Static microtiter plate biofilm assay performed to detect the biofilm formation, followed by scanning electron microscopy.

Results: Royal jelly effectively inhibited the viability of both strains from a concentration of 25%. The highest production of pyocyanin was observed in the subinhibitory concentration group 6.25%, which gradually decreased along with the decrease of royal jelly concentration. Results of one-way ANOVA tests differed significantly in pyocyanin production of the two strains between the royal jelly groups. Tukey HSD test showed concentrations of 12.5%, 6.25%, and 3.125% significantly increased pyocyanin production of ATCC 10145, and the concentrations of 12.5% and 6.25% significantly increased production of the clinical isolates. Concentrations of 12.5% and 6.125% significantly induced biofilm formation of P. aeruginosa ATCC 10145, in line with the results of the SEM analysis.

Conclusions: The royal jelly concentration of 25% or higher inhibits bacterial growth; however, the subinhibitory concentration increases pyocyanin production and biofilm formation in P. aeruginosa. It is advisable to determine the appropriate concentration of royal jelly to obtain beneficial virulence inhibiting activity.
Current situation of vaccine injury compensation program and a future perspective in light of COVID-19 and emerging viral diseases
Authors: Crum Tommie , Mooney Kirsten , Tiwari Birendra R.
Published: December 2021

Background: Vaccines have had a great impact on disease prevention and reducing mortality. Very rarely, vaccines also can result in serious adverse effects. In consideration of this fact, vaccine injury compensation programs have been implemented in many countries to compensate a vaccinee for associated adverse effects. The existing vaccine injury compensation system addresses routine immunization schemes. However, there are rising concerns about the compensation for adverse effects caused by new vaccines such as those developed for coronavirus disease 2019 (COVID-19). This review focuses on vaccine injury compensation programs and highlights the necessity to include all upcoming new vaccines for COVID-19 and other emerging viral diseases in the compensation schemes.

Methods: Published articles relating to vaccine compensation injury programs, vaccines, injuries, disabilities, illnesses, and deaths resulting from vaccination were searched in data bases. Through a careful review of the abstracts, 25 relevant articles were selected for analysis.

Results: We identified 27 countries on four continents with vaccine injury compensation schemes: 17 countries in Europe, 7 countries in Asia, the United States, a Canadian Province and New Zealand. No programs were identified in Africa and in South America. Program design, funding, and eligibility for compensation vary vastly between countries. We identified 17 countries operating well-established vaccine injury compensation programs. However, minimal information is available on numerous other countries.

Conclusion: We conclude that the vaccine injury compensation programs are available in limited number of countries across four continents - mostly in Europe. Lack of standard approach and scope of injury prevention and compensation programs across the countries exists. Some important limitations include limited scientific material, which hindered our research. Therefore, additional data concerning payout for each type of injury and the number of claimants related to a specific vaccine injury worldwide could provide a more comprehensive analysis.
An informational sociobiological explanation of the constitution of the human body
Authors: Moya-Salazar Jeel , Contreras-Pulache Libertad , Lam-Figueroa Nelly , Contreras-Pulache Hans
Published: December 2021

Background: Pedro Ortiz (1933-2011), in the latest four decades of his life, developed the Informational Sociobiological Theory (IST) in a university teaching context that became the foundation of post-grade studies in neuroscience in Peru. The IST looks for a totality explanation of the phenomena of the universe proposes an explanation of the constitution of the human body. In what consist this explanation of the configuration of the human body?

Methods: A bibliographical qualitative study was conducted starting from primary documental sources. It was considered among the sources, all related to the editorial project Books of Social Psychobiologic (elaborated by Ortiz during the first decade of this age). The results have been presented across a conceptual analysis, narrative and graphic, oriented to expose Ortiz’ ideas in relation to the human body’s morphology.

Results: The structural architecture of the human body, and in particular in one person; shows five levels of complexity which begins in cells, the intercellular matrix, the neural system, the paleocortical psyche, and neocortical psyche. In this involve explanation, the organs of the body are essentially tissue systems, and are integrated (subsumed) at the neural level (which informationally goes through the plexuses, ganglia, and subcortical nuclei). The two levels of superior complexity to the neural system, are the space of the psychic activity, unconscious and conscious, which is suprastructurally to all bodily structures. Ortiz is settled on a different monism: that guides us to imagine and think that all psychic activity is suprastructural to the body.

Conclusions: There is an original explanation of the human body within the IST. This informational morphology dialogues with the knowledge of biology, neurology, anatomy, physiology, embryology, and histology, and is proposed as a structuring element in all the conceptual architecture that represents the IST.
Mobile perceived trust mediation on the intention and adoption of FinTech innovations using mobile technology: A systematic literature review
Authors: Dawood Hatim M. , Liew Chee Yoong , Lau Teck Chai
Published: December 2021

The banking and financial sectors have witnessed a significant development recently due to financial technology (FinTech), and it has become an essential part of the financial system. Many factors helped the development of this sector, including the pandemics such as Covid-19, the considerable increasing market value of the FinTech sector worldwide, and new technologies such as blockchain, artificial intelligence, big data, cloud computing and mobile technology. Moreover, changes in consumer's preferences, especially the Z-generation (digital generation). FinTech shifted the traditional business models to mobile platforms characterized by ease of access and swift transactions. Mobile technology became the main backbone for FinTech innovations and acts as a channel to deliver FinTech services that overcome all geographical and timing barriers, thus enhancing financial inclusion. Mobile perceived Trust (MPT), or the trust in using financial business models via mobile technology, is a crucial factor in the FinTech context that has mediation effects on the intention and adoption of different FinTech business models. Unfortunately, few studies have explored MPT mediations on consumers' intention to adopt FinTech innovations using mobile technology. Typically, many studies examined trust/MPT as an independent and unidirectional variable and investigated its effects on behaviour intention without predicting its mediation effects. This study aimed to develop a systematic literature review on MPT mediation in FinTech, focusing on the period from 2016 and 2021, in journals ranked Q1 and Q2, and known-based theories such as the technology acceptance model, the unified theory of acceptance and use of technology, and the mobile technology acceptance model. This study found that only four articles were published in Q1 and Q2 journals. In these articles, the MPT was used as a mediator, and its effects were measured on the intention and adoption of the behaviour.
Slinker: Visualising novel splicing events in RNA-Seq data
Authors: Schmidt Breon , Cmero Marek , Ekert Paul , Davidson Nadia , Oshlack Alicia
Published: December 2021

Visualisation of the transcriptome relative to a reference genome is fraught with sparsity. This is due to RNA sequencing (RNA-Seq) reads being predominantly mapped to exons that account for just under 3% of the human genome. Recently, we have used exon-only references, superTranscripts, to improve visualisation of aligned RNA-Seq data through the omission of supposedly unexpressed regions such as introns. However, variation within these regions can lead to novel splicing events that may drive a pathogenic phenotype. In these cases, the loss of information in only retaining annotated exons presents significant drawbacks. Here we present Slinker, a bioinformatics pipeline written in Python and Bpipe that uses a data-driven approach to assemble sample-specific superTranscripts. At its core, Slinker uses Stringtie2 to assemble transcripts with any sequence across any gene. This assembly is merged with reference transcripts, converted to a superTranscript, of which rich visualisations are made through Plotly with associated annotation and coverage information. Slinker was validated on five novel splicing events of rare disease samples from a cohort of primary muscular disorders. In addition, Slinker was shown to be effective in visualising deletion events within transcriptomes of tumour samples in the important leukemia gene, IKZF1. Slinker offers a succinct visualisation of RNA-Seq alignments across typically sparse regions and is freely available on Github.
A software-computational neural network tool for predicting the electromagnetic state of the polar magnetosphere, taking into account the process that simulates its slow loading by the kinetic energy of the solar wind
Authors: BARKHATOV NIKOLAY , REVUNOV SERGEY
Published: December 2021

The auroral activity indices AU, AL, AE, introduced into geophysics at the beginning of the space era, although they have certain drawbacks, are still widely used to monitor geomagnetic activity at high latitudes. The AU index reflects the intensity of the eastern electric jet, while the AL index is determined by the intensity of the western electric jet. There are many regression relationships linking the indices of magnetic activity with a wide range of phenomena observed in the Earth's magnetosphere and atmosphere. These relationships determine the importance of monitoring and predicting geomagnetic activity for research in various areas of solar-terrestrial physics. The most dramatic phenomena in the magnetosphere and high-latitude ionosphere occur during periods of magnetospheric substorms, a sensitive indicator of which is the time variation and value of the AL index. Currently, AL index forecasting is carried out by various methods using both dynamic systems and artificial intelligence. Forecasting is based on the close relationship between the state of the magnetosphere and the parameters of the solar wind and the interplanetary magnetic field (IMF). This application proposes an algorithm for describing the process of substorm formation using an instrument in the form of an Elman-type ANN by reconstructing the AL index using the dynamics of the new integral parameter we introduced. The use of an integral parameter at the input of the ANN makes it possible to simulate the structure and intellectual properties of the biological nervous system, since in this way an additional realization of the memory of the prehistory of the modeled process is provided.
Corporate Citizen in Political Discourse Amidst the Pandemic
Authors: Sharahina L.
Published: December 2021

The wisdom of reviewing corporations, which execute strategic programs of corporate sustainability, as an important actor of political communications in postindustrial society is justified in the article. The basic features of corporate sustainability, corporate social responsibility, and corporate citizenship concepts, the role of strategic communications under international ESG-discourse are outlined. The comparative analyses of Russian companies, participating Global Compact Network, social investments during COVID-19 pandemic is based on case studies, transparent nonfinancial reporting, and expert interviews. Social projects and programs of X5 Retail Group, Severstal’, Norilsk Nikel, United Metallurgic Company were studied. These companies’ basic business activities were established in industrial society. As the result of the research, based on process sociology (N. Elias), mediatization (A. Hepp), and communicative rationality (Ju. Habermas) approaches, the role of corporate citizens in communicative figurations of the network society formation and their subjectivity in political communications acquiring. The focus is made on COVID-19 pandemic influence on communication infrastructures with the studied companies’ stakeholders transformation.
Jako „przestroga przed demontażem demokracji”. Uwagi i refleksje na marginesie polskiej edycji krytycznej Mein Kampf Adolfa Hitlera, w przekładzie i opracowaniu Eugeniusza Cezarego Króla
Authors: Bartnicka Alicja
Published: December 2021

Celem niniejszego artykułu jest omówienie oraz próba oceny opublikowanej nakładem wydawnictwa Bellona polskiej edycji krytycznej Mein Kampf Adolfa Hitlera. Przekładu i opracowania podjął się Eugeniusz Cezary Król – wybitny niemcoznawca, który wcześniej dokonał już wyboru i tłumaczenia Dzienników Josepha Goebbelsa. Przygotowane przez niego wydanie Mein Kampf jest pierwszym pełnym polskim przekładem pracy Hitlera, który dodatkowo opatrzono naukowym komentarzem i aparatem krytycznym.
Incorporating the Relation into the Language?
Authors: Estrada-González Luis , Giordani Alessandro , Jarmużek Tomasz , Klonowski Mateusz , Sedlár Igor , Tedder Andrew
Published: December 2021

In this paper we discuss whether the relation between formulas in the relating model can be directly introduced into the language of relating logic, and present some stances on that problem. Other questions in the vicinity, such as what kind of functor would be the incorporated relation, or whether the direct incorporation of the relation into the language of relating logic is really needed, will also be addressed.
Pure Variable Inclusion Logics
Authors: Paoli Francesco , Pra Baldi Michele , Szmuc Damian
Published: December 2021

The aim of this article is to discuss pure variable inclusion logics, that is, logical systems where valid entailments require that the propositional variables occurring in the conclusion are included among those appearing in the premises, or vice versa. We study the subsystems of Classical Logic satisfying these requirements and assess the extent to which it is possible to characterise them by means of a single logical matrix. In addition, we semantically describe both of these companions to Classical Logic in terms of appropriate matrix bundles and as semilattice-based logics, showing that the notion of consequence in these logics can be interpreted in terms of truth (or non-falsity) and meaningfulness (or meaninglessness) preservation. Finally, we use Płonka sums of matrices to investigate the pure variable inclusion companions of an arbitrary finitary logic.
Informal Provability, First-Order BAT Logic and First Steps Towards a Formal Theory of Informal Provability
Authors: Pawlowski Pawel , Urbaniak Rafal
Published: December 2021

BAT is a logic built to capture the inferential behavior of informal provability. Ultimately, the logic is meant to be used in an arithmetical setting. To reach this stage it has to be extended to a first-order version. In this paper we provide such an extension. We do so by constructing non-deterministic three-valued models that interpret quantifiers as some sorts of infinite disjunctions and conjunctions. We also elaborate on the semantical properties of the first-order system and consider a couple of its strengthenings. It turns out that obtaining a sensible strengthening is not straightforward. We prove that most strategies commonly used for strengthening non-deterministic logics fail in our case. Nevertheless, we identify one method of extending the system which does not.
Urlop macierzyński a praca zarobkowa
Authors: Napiórkowska Anna
Published: December 2021

Urlop macierzyński ma w prawie pracy co do zasady obowiązkowy charakter. W tym czasie pracownicy nie mogą wykonywać pracy zarobkowej w ramach stosunku pracy, mają wówczas prawo do zasiłku macierzyńskiego z ubezpieczenia chorobowego. W artykule, odnosząc się do wyroku Sądu Najwyższego z dnia 21 października 2020 r., zwrócono uwagę na problem podjęcia pracy zarobkowej w ramach stosunku pracy przez pracownicę w czasie urlopu macierzyńskiego. Podkreślono, że w takiej sytuacji pracownica ma prawo do wynagrodzenia za wykonaną pracę. Pracownica ma także wówczas prawo do zasiłku macierzyńskiego.
Wyłączenie lub ograniczenie wstąpienia spadkobiercy wspólnika do spółki z o.o. – zagadnienia wybrane
Authors: Suliński Grzegorz
Published: December 2021

Spółka z ograniczoną odpowiedzialnością jako osoba prawna kontynuuje swój byt prawny niezależnie od losów jej wspólników. W szczególności zatem śmierć wspólnika nie stanowi – co do zasady – przyczyny jej rozwiązania i w konsekwencji zakończenia działalności. Wspólnik może także określić krąg osób, które wstąpią w jego prawa i obowiązki spółkowe na wypadek jego śmierci. Instrumenty umożliwiające takie wskazanie znajdują się zarówno w przepisach k.c., jak i k.s.h. Obok określenia porządku dziedziczenia w drodze sporządzenia testamentu wspólnicy mogą również zawrzeć w umowie spółki klauzulę wyłączającą lub ograniczającą wstąpienie ich spadkobierców do spółki. Ciężar uregulowania instytucji wyłączenia lub ograniczenia wstąpienia spadkobierców do spółki spoczywa na wspólnikach. Klauzula umowna dotycząca tego zagadnienia powinna precyzyjnie i szczegółowo określać zasady postępowania z udziałami wyłączonymi od dziedziczenia. Niespełnienie tego postulatu rodzi istotne trudności interpretacyjne wywołujące wątpliwości co do skutku wywieranego przez taką klauzulę. Skutek ten uzależniony jest w szczególności od rodzaju ograniczenia wstąpienia spadkobiercy do spółki. Należy postulować rozważenie ingerencji ustawodawczej w treść przepisu art. 183 k.s.h. poprzez rozbudowanie wymogów dotyczących treści klauzuli wyłączającej lub ograniczającej wstąpienie spadkobierców do spółki w kierunku uszcze-gółowienia sposobu postępowania przy przejmowaniu udziałów w spółce, w stosunku do których umowa spółki wyłączyła dziedziczenie.
Cywilnoprawna odpowiedzialność członków organów prostej spółki akcyjnej wobec spółki
Authors: Węgliński Konrad
Published: December 2021

Z dniem 1 lipca 2021 r. katalog spółek handlowych na gruncie prawa polskiego został rozszerzony o nowy typ spółki, jakim jest prosta spółka akcyjna. W założeniu prosta spółka akcyjna ma stanowić nowoczesną formę niepublicznej spółki kapitałowej przeznaczonej w szczególności do realizacji innowacyjnych przedsięwzięć oraz tzw. startupów. Przepisy regulujące funkcjonowanie prostej spółki akcyjnej zawierają nowatorskie rozwiązania na tle dotychczasowych spółek funkcjonujących w polskim prawie, w tym m.in. możliwość swobodnego kształtowania przez akcjonariuszy wewnętrznej organizacji spółki poprzez wybór monistycznego albo dualistycznego systemu organów spółek, a także uregulowanie cywilno-prawnej odpowiedzialności członków organów prostej spółki akcyjnej za szkody wyrządzone spółce zgodnie z zasadą biznesowej oceny sytuacji (ang. business judgment rule). Celem artykułu jest omówienie zasad ponoszenia cywilnoprawnej odpowiedzialności piastunów organów prostej spółki akcyjnej wobec spółki ze szczególnym uwzględnieniem odmienności w stosunku do regulacji dotyczących odpowiedzialności funkcjonariuszy spółki z ograniczoną odpowiedzialnością (art. 293 § 1 k.s.h.) oraz spółki akcyjnej (art. 483 § 1 k.s.h.). W artykule podjęto także próbę oceny najdonioślejszego legislacyjnego novum wprowadzonego do polskiego prawa wraz z wejściem w życie przepisów o prostej spółce akcyjnej, jakim jest unormowanie zasady biznesowej oceny sytuacji w art. 300(125) § 2 k.s.h.
Peranan Budaya Hukum dalam Penanggulangan Tindak Pidana Perjudian Sabung Ayam dan Perjudian Kartu di Desa Adiwarno Kecamatan Buayan Kabupaten Kebumen
Authors: Wardani Aldila Rizky Widya , Khakim Mufti
Published: December 2021

Judi berbahaya bagi masyarakat, bangsa, dan negara, serta sangat kontradiktif dengan agama, etika dan moralitas. Berbagai bentuk perjudian telah berkembang dalam kehidupan sehari-hari, banyak yang melakukannya baik secara terbuka maupun sembunyi-sembunyi. Masyarakat menilai bahwa perjudian adalah sesuatu yang biasa, tidak melanggar hukum, tidak dikeluarkan oleh masyarakat setempat, bahkan menganggap bahwa perjudian hanyalah pelanggaran kecil.Penelitian ini menggunakan penelitian normatif empiris. Sumber data yang digunakan adalah sumber data primer dan sekunder yang diperoleh dari bahan hukum primer, sekunder, dan tersier. Metode pengumpulan data primer dilakukan dengan wawancara dan metode pengambilan data sekunder dilakukan dengan menggunakan dokumen terkait.Hasil penelitian ini menyatakan bahwa: (i) Masyarakat memandang bahwa perjudian dianggap sebagai perbuatan biasa dan menjadi mata pencaharian sehari-hari. Masyarakat memandang dan menghargai perjudian sebagai rekreasi dan menerima keberadaannya, yang mereka hargai hanya berdasarkan keuntungannya, tanpa mempertimbangkan dampak negatifnya. (ii) Penanganan Judi Sabung Ayam dan Judi Kartu menggunakan Pendekatan Ekonomis, Hukum, Sosial, dan Keagamaan. Orang-orang mengadakan konferensi untuk memberikan himbauan / peringatan secara langsung maupun tidak langsung.
The ‘new’ NHS: opportunity or threat for advanced clinical practice?
Authors: Duncan Monica
Published: December 2021

Monica Duncan discusses the implications of the Health and Care Bill 2021 for advanced clinical practice and professional regulation.
A paramedic in public health
Authors: Cowell Sian
Published: December 2021

In our last segment of Paramedic Roles, Sian Cowell shares her journey towards public health after a COVID-19 infection and subsequent redeployment catapulted her in this unconventional but exciting direction