bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECT OF VARIATION OF LUBRICANT CONCENTRATION (MAGNESIUM STEARATE) ON THE PHYSICAL QUALITY OF METOCLOPRAMID HCl TABLETS WITH DIRECT PRINTING METHOD
Authors: Puspadina Valiandri , Budi Legowo Deny , Fitriany Erna , Priyoherianto Andri , Damayanti Winda
Published: May 2021

Metoclopramide HCl is used to relieve nausea and vomiting. Market availability in the form of tablets, syrup and injection. The most preferred drug use by patients is oral medication because of its ease of use. Chewable tablets are a new product as an alternative for treatment in pediatric and adult patients who have difficulty swallowing drugs. This study aims to formulate the chewable tablet preparations of metoclopramide HCl using variations in lubricant concentrations. The variations of magnesium stearate with concentrations of 1%, 2%, and 3% using the direct printing method made to obtain a better physical quality test including organoleptics, weight uniformity, uniformity of size, tablet hardness, tablet brittleness, tablet crush time, uniformity of content. The results of the physical quality test were statistically analyzed using one way ANOVA to determine the effect of variations in the concentration of lubricants on the characteristics of chewable tablets. The results showed that variations in the concentration of magnesium stearate lubricant in the manufacture of metoclopramide HCl chewable tablets had an effect on the physical quality of metoclopramide HCl chewable tablets. The concentration of magnesium stearate which produces metoclopramide HCl chewable tablets with good physical properties is 2%.
МАЛЕ І СЕРЕДНЄ ПІДПРИЄМНИЦТВО – ІНСТИТУТ РОЗВИТКУ НАЦІОНАЛЬНОЇ ЕКОНОМІКИ
Authors: Бережницька У.Б.
Published: May 2021

Стаття присвячена визначення ролі та значення малого і середнього підприємництва (МСП) у національній економіці, зважаючи на актуальний стан розвитку даного сектора економічної системи України. При наявності обґрунтованих теорій щодо малої економіки, науковці і практики по різному трактують малий і середній бізнес, а окремі твердження частково або зовсім не отримують свого відображення на практиці. Використовуючи гіпотетично-дедуктивну методологію, методи аналізу та синтезу, логічного узагальнення, систематизації, порівняння, графічного відображення даних, сформовано авторське бачення щодо необхідності розгляду МСП в якості інституту розвитку національної економіки. Такий підхід дозволив, окрім підтвердження чи спростування висловлених гіпотез щодо МСП, комплексно оцінити стан розвитку малого і середнього бізнесу в Україні, виділити найболючіші проблеми і вказати напрям їх вирішення.
Overview of Ca2+ signaling in lung cancer progression and metastatic lung cancer with bone metastasis
Authors: Tran Manh Tien
Published: May 2021

Intracellular Ca2+ ions that are thought to be one of the most important second messengers for cellular signaling, have a substantial diversity of roles in regulating a plethora of fundamental cellular physiology such as gene expression, cell division, cell motility and apoptosis. It has been suggestive of the Ca2+ signaling-dependent cellular processes to be tightly regulated by the numerous types of Ca2+ channels, pumps, exchangers and sensing receptors. Consequently, dysregulated Ca2+ homeostasis leads to a series of events connected to elevated malignant phenotypes including uncontrolled proliferation, migration, invasion and metastasis, all of which are frequently observed in advanced stage lung cancer cells. The incidence of bone metastasis in patients with advanced stage lung cancer is estimated in a range of 30% to 40%, bringing about a significant negative impact on both morbidity and survival. This review dissects and summarizes the important roles of Ca2+ signaling transduction in contributing to lung cancer progression, and address the question: if and how Ca2+ signaling might have been engaged in metastatic lung cancer with bone metastasis, thereby potentially providing the multifaceted and promising solutions for therapeutic intervention.
Goods Robots Based On Color Using Microcontroller Atmega 328
Authors: Rahayu Novi , Sumarni Ade Titin
Published: May 2021

Robot is an electrical or electronic mechanical device that works automatically that can work alone without outside control. By using robots in production activities, the process will be more efficient and effective. In this study, robots are made using a microcontroller as a robot controller and color detector to separate goods based on color. Color sensor is useful for getting color data. The detected color consists of Red, Green, Blue, all colors are processed in a microcontroller that functions as the brain in the robot that is made.
Product Codefication Accuracy With Cosine Similarity And Weighted Term Frequency And Inverse Document Frequency (TF-IDF)
Authors: Sintia Sintia , Defit Sarjon , Nurcahyo Gunadi Widi
Published: May 2021

In the SiPaGa application, the codefication search process is still inaccurate, so OPD often make mistakes in choosing goods codes. So we need Cosine Similarity and TF-IDF methods that can improve the accuracy of the search. Cosine Similarity is a method for calculating similarity by using keywords from the code of goods. Term Frequency and Inverse Document (TFIDF) is a way to give weight to a one-word relationship (term). The purpose of this research is to improve the accuracy of the search for goods codification. Codification of goods processed in this study were 14,417 data sourced from the Goods and Price Planning Information System (SiPaGa) application database. The search keywords were processed using the Cosine Similarity method to see the similarities and using TF-IDF to calculate the weighting. This research produces the calculation of cosine similarity and TF-IDF weighting and is expected to be applied to the SiPaGa application so that the search process on the SiPaGa application is more accurate than before. By using the cosine sismilarity algorithm and TF-IDF, it is hoped that it can improve the accuracy of the search for product codification. So that OPD can choose the product code as desired
Stützen-Riegel-Knoten ohne und mit geklebter CFK-Verstärkung – Versuche und numerische Simulationen/Column-beam joints strengthened without and with bonded CFRP reinforcement – experiments and numerical simulations
Authors: Fasoulakis Zacharias , Pasternak Hartmut , Vayas Ioannis , Li Zheng
Published: May 2021

Im Rahmen des Forschungsprojekts “Hybride Verstärkungsmaßnahmen und innovative Messmethoden im Stahlbau” wurden Versuche und numerische Simulationen an biegesteifen Stützen-Riegel-Knoten durchgeführt. Es wurden Innen- und Aussenknoten untersucht, bei denen ein beziehungsweise zwei Riegel an die Stütze angeschlossen ist. Bei den ersteren wird bei der Traglast die Biegetragfähigkeit der Träger erreicht, bei den letzteren die Schubtragfähigkeit des Knotenbleches. Für jeden Knotentyp wurden zwei Versuche durchgeführt, einer unverstärkt mit reinem Stahlprofil, der andere verstärkt mithilfe von geklebten kohlefaserverstärkten Kunststoffen (CFK). Es zeigt sich, dass bei den unverstärkten Knoten gewisse Reserven gegenüber den Normen infolge Materialverfestigung und Widerstände im überkritischen Bereich existieren. Bei den verstärkten Knoten wurde eine Erhöhung der Tragfähigkeit beobachtet, die jedoch wegen vorzeitigen Lösens der CFK-Lamellen von der Stahloberfläche zu gering ausfiel.
Einfluss der Schallbelastung beim Einsatz mobiler Luftreiniger (MLR) auf die Freisetzung von SARS-CoV-2-Viren in Unterrichtsräumen/Effects of noise exposure when using mobile air purifiers (MAP) on the release of SARS-CoV-2 viruses in classrooms
Authors: Steffens Thomas , Seipp Hans-Martin
Published: May 2021

Für den Lernerfolg der Schüler/-innen und die gesundheitsverträglichen Arbeitsbedingungen der Lehrkräfte im Unterricht existieren hohe akustische Anforderungen, wobei Schall aus Raumlufttechnischen Anlagen (RLT-Anlagen) auf ≤ 35 dB(A) begrenzt ist. Jedoch sind für Unterrichtsräume umfänglich erhebliche bauliche Defizite belegt und insbesondere zu hohe Nachhallzeiten identifiziert worden. Dauerschallerzeugende Mobile Luftreiniger (MLR) würden die vielerorts bereits überschrittenen Belastungsgrenzen zusätzlich verletzen. Je nach MLR-Anzahl und Dauerschallpegel sind die Lehrkräfte gezwungen, lauter zu sprechen (Lombard-Effekt), was zu einer wesentlichen Erhöhung freigesetzter (Virus-)Partikel führt. Um auch während des MLR-Dauerbetriebes mit 54 dB(A) die nach DIN 18041 erforderliche Sprachverständlichkeit an jedem Sitzplatz im Raum sicherzustellen, muss die Lehrkraft ihre Lautstärke erheblich steigern: In Abhängigkeit von der Position im Raum induzieren MLR um die 4,2- bzw. 11,2-fach höheren (Virus-)Lasten, denen alle im Unterricht Anwesenden ausgesetzt sind.
Akustikdecken – Alles Gute kommt von oben
Authors: Titzas Hermann
Published: May 2021

Die Akustikdecke trägt einen erheblichen Anteil zur Raumakustik bei und verbessert Kommunikation sowie Konzentration deutlich. Neben der Funktionalität ist diese auch elegant anzuschauen, ob gelocht oder geschlitzt. Ziel ist eine größtmögliche schallabsorbierende Wirkung, dies gelingt, wenn sie direkt im Schallverlauf angebracht wird. Der Fokus der Akustikdecke liegt eindeutig auf den bekanntesten, raumakustischen Kriterien – Optimierung der Nachhallzeit, Abklingraten und Sprachverständlichkeit.
Herausforderungen bei der Bestimmung der Mindestzündenergie hybrider Gemische
Authors: Wolf Christian , Marx Marcus , Gabel Dieter
Published: May 2021

Eine reproduzierbare und verlässliche Bestimmung der sicherheitstechnischen Kenngrößen hybrider Gemische ist von enormer Bedeutung für die Festlegung von Sicherheitsmaßnahmen in der Praxis. Die Herausforderung besteht bislang darin, den genauen Einfluss des Brenngases bei Konzentrationen weit unterhalb der unteren Explosionsgrenze auf die Mindestzündenergie des brennbaren Staubs zu quantifizieren, da die derzeit für die Prüfung brennbarer Stäube zugelassenen Prüfapparaturen nicht für die Betrachtung hybrider Gemische ausgelegt sind. Im Folgenden wird eine Versuchsdurchführung inklusive der dazugehörigen Apparatur vorgeschlagen, mit der dies verlässlich und reproduzierbar erreicht werden kann. Anschließend wird die beschriebene Prüfapparatur durch verschiedene Versuchsreihen hinsichtlich ihrer Plausibilität und Anwendbarkeit geprüft, sowie zusätzliche Verbesserungsvorschläge unterbreitet.
KAS-18 – und was dann?
Authors: Bahn Steffen , Harney Jürgen , Heuer Iris-Gesine , Schalau Bernd , Wolf Jessika , Wolff Jens-Martin
Published: May 2021

In zentraler Lage der Stadt Holzminden befinden sich mehrere Betriebsbereiche, deren angemessene Sicherheitsabstände ein Großteil der Stadt überdecken. In einem Projekt der Gewerbeaufsichtsämter Hannover und Hildesheim, der Stadt Holzminden und der BAM wurde eine transparente, nachvollziehbare Methode zur ersten Vorprüfung von Bauanfragen innerhalb des angemessenen Sicherheitsabstands entwickelt. Die Methode kann auch in Stadtentwicklungskonzepten Eingang finden. Es werden die Methode und die bisherigen Erfahrungen in der Praxis vorgestellt.
Lüftungskonzepte: Wie CO2 Ampeln zum wirksamen Infektionsschutz beitragen
Authors: Wenten Matthias
Published: May 2021

Häufiges und richtiges Lüften ist während der Corona-Pandemie besonders wichtig. Es ist neben weiteren Maßnahmen wie dem Abstand halten und dem Tragen medizinischer Gesichtsmasken ein essenzieller Bestandteil des Infektionsschutzes. Durch die Einhaltung von Lüftungskonzepten kann die Verbreitung des Virus in Innenräumen verhindert werden. Davon betroffen sind besonders Arbeitsplätze, die nicht ins Homeoffice verlagert werden können. Hier haben sich CO2 Ampeln als hilfreiche Ergänzung zu Lüftungskonzepten erwiesen. Unter den verschärften Maßnahmen zu Pandemie-Zeiten stellen sie somit einen wichtigen Baustein für sicheres Arbeiten dar.
Sandstone dykes in the Vang granite, northwestem Bornholm (Denmark)
Authors: Katzung Gerhard
Published: May 2021

Recently discovered sandstone dykes in the Vang granite of northwestern Bornholm
are very similar to those in the Svaneke granite nearby Listed, with regard to
strike direction and fillings.
Resistivity and georadar mapping of lacustrine and
glaciofluvial sediments in the late-glacial to postglacial Store
Amose basin, Denmark
Authors: Sten Erik , Thybo Hans , Nygaard Nanna Noe
Published: May 2021

Resistivity profiling, resistivity sounding, georadar profiling and analyses of
borings are used in a sedimentological and geomorphological study of shallow
subsurface deposits in the proximal (southeastern) part of the Store Amose
lacustrine basin in eastern Denmark. Areas of low, intermediate and high resistivities are located by resistivity profiling. Low-resistivity areas (type I) correspond
to a thick unit of water-saturated lake sediments (fine detritus gyttja and siltlclay)
which were deposited in a large lake system from the late Weichselian to the late
Holocene. In intermediate-resistivity areas (type II), a relatively thick top layer of
fresh-water peat and drifted gyttja or dry gyttja occurs. Fine-grained lake sediments,
drifted gyttja and peat are equivaIent to transparent facies and low penetration
(max. c. 2 m) in georadar profiles. Resistivity soundings indicate a shallower
high-resistive substratum of meltwater sand and gravel in type II areas than in
type I areas. The lake and fen sediments fil1 a highly irregular lake bottom relief,
interpreted to have been formed in glaciofluvial channel systems and as dead-ice
holes during the final Weichselian deglaciation. Sandy and gravelly domes and
ridges, interpreted as proximal glaciofluvial deposits, are exposed at the ground
surface in high-resistivity areas (type III). Convex surfaces of glaciofluvial bars
and sides of meltwater channels are distinct georadar reflectors. Shallow,
glaciofluvial bars were islands in the Holocene lake system and surrounding intermediate-resistivity areas represent shore zones of these islands (possible settlement areas).
STERILIZER CHAMBER SEBAGAI SALAH SATU ALAT PENCEGAHAN PENYEBARAN VIRUS COVID-19
Authors: Antara Made Adi Surya , Suteja I Wayan Arsa , Prabowo Agung
Published: May 2021

Seperti kita ketahui bersama virus Covid-19 yang menjadi musuh kita bersama di seluruh dunia. Banyak inovasi yang telah dilakukan untuk mencegah terjadinya penyebaran virus corona ini, salah satunya yaitu memanfaatkan disinfektan sebagai pencegah penyebaran virus. Disinfektan mengandung chlorin yang mampu mensterilkan benda-benda dari kuman, bakteri, dan virus. Banyak kalangan saat ini berusaha untuk membuat alat semprot disinfektan otomatis, higienis, dan aman bagi penggunaan bagi tubuh manusia. Salah satunya yaitu sistem alat yang otomatis dan bisa disemprotkan ke seluruh tubuh dengan menggunakan sterilizer chamber yang lebih sempurna dan lebih simple dibandingkan dengan cuci tangan. Alat yang diperlukan untuk membuat sebuah chamber yaitu sebuah bilik atau ruangan yang terbuat dari baja ringan, plastik tebal sebagai pelapis bilik, pompa spray nozzle tipe 12 V sebanyak 15 titik, sensor gerak berbasis switch pada komponen mosfet sebagai sistem penyemprotan, dan bahan disinfektan dengan campuran tertentu. Susunan alat alat tersebut akan menghasilkan sterilizer chamber yang bekerja dengan cara menyemprotkan cairan disinfektan ke tubuh manusia secara otomatis ketika ada orang yang masuk ke dalam sterilizer chamber yang mana akan dibaca oleh sensor gerak yang diletakkan diatas chamber. Harapan pembuatan alat ini yaitu semoga dapat menekan serta mencegah penyebaran virus Covid-19. Sterilizer chamber dapat ditempatkan dipintu masuk tempat umum seperti kampus, pasar, dan perkantoran.
PENGEMBANGAN POLA DASAR BATIK DOLLY
Authors: Damajanti Maria Nala
Published: May 2021

Kawasan Dolly yang terletak di Kelurahan Putat Jaya, Kecamatan Sawahan saat inidikenal juga karena batik produksi masyarakat setempat. Walaupun batik baru mulai dikenalkandalam lima tahun terakhir karya mereka telah sering terlihat pada pameran batik maupun padabeberapa pusat souvenir di Surabaya. Melalui pendalaman diketahui bahwa keterbatasankeahlian desain menjadi latar belakang para pembatik yang rata-rata adalah Ibu rumah tanggasekaligus warga terdampak penutupan lokalisasi. Para pembatik membutuhkan desain baru agarlebih berkembang dan lebih dapat menarik minta pembeli. Untuk itulah abdimas ini dilakukanoleh tim dengan berlatar belakang Desain Komunikasi Visual hingga kemudian yang dihasilkanadalah pengembangan motif baru berciri khas Jarak Dolly dan juga mengadaptasi ikon KotaSurabaya. Pendekatan metode design thinking dianggap paling sesuai dalam proses desain hinggarealisasinya dan hasil akhir berupa pola batik berciri lokal dapat dimanfaatkan untuk jangkapanjang dalam pengembangan selanjutnya.
PENINGKATAN NILAI TAMBAH DAN PENGEMBANGAN USAHA PRODUK AGROBISNIS BAWANG MERAH
Authors: HENDARTO TOTOK , D YOGANTARA S
Published: May 2021

Bawang merah (Allium cepa var aggregatum) sangat dikenal dalam kehidupan sehari-hari masyarakat di Indonesia, digolongkan kedalam sayuran utama di masyarakat. dianggap komoditas agrobisnis unggulan karena memiliki fungsi dan manfaat sangat luas. Besarnya potensi pasar produk agrobisnis bawang merah tersebut, juga dirasakan bapak Arukhan dan ibu Siti Maisaroh di Desa Baureno Kec Jatirejo Kab Mojokerto. Permasalahan pengembangannya meliputi : 1) bidang manajemen usaha, 2) bidang keuangan dan 3) bidang pemasaran. Solusi masalah diantaranya : diversifikasi produk usaha, introdusir penggunaan alat pencacah produk usaha dan teknik pengemasan, Metode digunakan adalah 1. penyampaian informasi dan pelatihan, 2. pendampingan dan simulasi agar didapatkan hasil produksi yang terbaik. Hasil menunjukkan penjualan bawang goreng lebih menguntungkan jika dibandingkan penjualan bawang merah mentah. Selisih keuntungannya sebesar Rp. 7.000 per kilogramnya. Kemasan yang diminati adalah kemasan 100 gram, kemudian 50 gram dan terakhir kemasan 150 gram. Penjualan bawang goreng, konsumen berkecenderungan menyukai rasa original jika dibandingkan bawang goreng tepung. Bawang goreng rasa original memberikan nilai keuntungan Rp. 450 per bulannya dan bawang goreng tepung Rp. 56.000.
PEMODELAN LITERASI MEMBACA SISWA DI DAERAH TERPENCIL MENGGUNAKAN REGRESI LOGISTIK BINER
Authors: Wulandari Sri Pingit , Wildani Zakiatul , Prastuti Mike , Aridinanti Lucia , Retnaningsih Sri Mumpuni , Ratih Iis Dewi , Kustantin Sukriyah , Zullah Vies Sata , Kurniasari Septiana Vera , Pradana Aditya
Published: May 2021

Peningkatan kualitas pendidikan memiliki peran penting dalam mempercepat tujuan pembangunan berkelanjutan atau yang lebih dikenal dengan Sustainable Development Programs (SDGs) tidak hanya di Indonesia tetapi juga di setiap negara di dunia. Namun, kualitas pendidikan di Indonesia masih di bawah negara tetangga seperti Malaysia atau Thailand yang ditunjukkan dengan angka melek huruf yang masih rendah. Hal ini terjadi disebabkan oleh banyak faktor, seperti kondisi psikologis atau lingkungan keluarga. Apalagi keterbatasan akses, fasilitas, dan sumber daya manusia di beberapa daerah terpencil di Indonesia juga mempengaruhi hal tersebut. Tujuan utama dari penelitian ini adalah untuk menganalisis faktor-faktor apa saja yang signifikan mempengaruhi literasi membaca siswa SDN kelas 1 di Kecamatan Nonggunong, Pulau Sapudi, Kabupaten Sumenep. Hasil dari kegiatan ini diharapkan dapat menjadi tolak ukur dalam penyelenggaraan dan evaluasi isu pendidikan khusunya didaerah terpencil demi tercapainya tujuan SDGs di masa depan. Adapun metode yang digunakan adalah regresi logistik biner. Hasil penelitian menunjukkan tiga faktor berpengaruh signifikan terhadap skor literasi siswa yaitu usia, jenis kelamin, serta tingkat kesukaan membaca siswa dengan persentase ketelitian klasifikasi model sebesar 81,8%.
PENINGKATAN KESADARAN KEBIASAAN PENGGUNAAN MASKER UNTUK PENCEGAHAN COVID-19 MELALUI GERAKAN PEMBAGIAN MASKER DI WILAYAH PASAR TRADISIONAL DENPASAR, BALI
Authors: Hanindharputri Made Arini , Lestari Ni Putu Emilika Budi , Lestari Putu Astri
Published: May 2021

Untuk menghadapi virus Covid 19 yang terus meningkat dan menyebar secara masif, pemerintah di seluruh dunia, termasuk Indonesia, menghimbau dan mewajibkan masyarakatnya untuk mematuhi protokol kesehatan termasuk dalam penggunaan masker dalam kegiatan sehari-hari. Masker menjadi sarana wajib yang dipakai masyarakat terlebih lagi dikonfirmasi bahwa virus Covid 19 dapat menular melalui udara (airbone). Namun, masyarakat Bali masih abai dalam penggunaan masker karena kurangnya edukasi. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan edukasi kepada masyarakat untuk selalu mematuhi protokol kesehatan di masa pandemi covid 19. Selain itu, pengabdian kepada masyarakat juga dapat meningkatkan jiwa sosial dosen dan mahasiswa Institut Desain dan Bisnis Bali, serta dapat meningkatkan kemampuan di bidang desain, dimana hasil karya civitas akademika Institut Desain dan Bisnis Bali dapat langsung dirasakan oleh masyarakat umum. Pengabdian kepada masyarakat dalam bentuk pembagian masker kain ini dilaksanakan di Pasar Yadnya, Kesiman karena pasar tradisional merupakan lokasi yang sering dikunjungi masyarakat dalam aktivitas perekonomian sehari-hari. Produksi masker kain dilakukan oleh dosen dan mahasiswa program studi Desain Mode yang kemudian dikemas dengan kemasan yang didesain oleh dosen dan mahasiswa Desain Komunikasi Visual, Institut Desain dan Bisnis Bali. Untuk memberikan edukasi, dirancang pula infografis berisi informasi secara visual mengenai protokol kesehatan dan cara mencuci masker kain. Penyerahan masker dilakukan secara simbolis kepada pengurus kelurahan Kesiman dan kepala pasar Yadnya. Selanjutnya dilakukan pembagian masker kepada pedagang dan pembeli di lingkungan pasar Yadnya, Kesiman.
The problem of subjectivity of values in the search for a universal environmental ethics
Authors: Yuksel Sarac Yesilada
Published: May 2021

Considering the relationship between the environment and morality, discussion of the matter of values is inevitable. Although there is no consensus on the intrinsic and instrumental characteristics of the value, the condition of talking about environmental ethics is that the environment carries not instrumental but intrinsic value. The problem of subjectivity of this value creates an ontological problem. Given that the value of what is valued depends on the preferences, interests, and attitudes of the valuers, it can lead to anthropocentric environmental ethics, which is an abusive approach style by environmental policymakers. On the other hand, the understanding that value is independent of the preferences, interests, and attitudes of the subject brings an objective approach but this makes it difficult to base environmental ethics on values ??and adds scientific aspects to environmental approaches. Scientific aspects are already discussed under some concepts such as sustainability, biodiversity, ecology, and environmental management. However, grounding these concepts on moral values ??and the formation of environmental ethics depends on emphasizing not only the scientific and objective but also its subjective side. This study explained the possibility of meeting the universality criterion in objective conditions despite the subjectivity of values because the way environmental ethics is adopted by everyone is only a universal environmental ethic.
A sociolinguistic analysis of verbal greetings, address forms and paralinguistic behaviours in Kisubi
Authors: Rwakakindo Ibrahim D.
Published: May 2021

This paper analyses the greeting system of Kisubi. It specifically seeks: to identify temporal greeting patterns in Kisubi; to determine whether age and gender do dictate the kind of verbal greetings, address forms and paralinguistic behaviours that are used in particular greeting events; to examine different kinship-specific verbal greetings, address forms and paralinguistic behaviours that are used in particular greeting events; and lastly, to assess the role of context in the Kisubi greeting system. Observation and face-to-face interview methods were used to gather data from 36 participants who were obtained using snowball sampling technique, and afterwards they were stratified into different strata depending on age, gender and educational status of a person. This stratification led to the attainment of authentic data. The obtained data were subjected to content analysis from which different themes emerged. It was established that there are four temporal chunks in Kisubi, each of which is associated with its own greeting term. Age, gender, context and kinship relations also determine the type of greeting terms and the honorifics or deferential terms to use. However, the use of honorifics and/or deferential terms is declining gradually.
Hausa phraseologisms as a structural property of language and cultural value
Authors: Pawlak Nina
Published: May 2021

The paper discusses phraseological units in Hausa as combinations of lexical units which have grammatical and cultural motivations. Its purpose is to identify language-specific types of structural phraseologisms and their culture-specific meanings. At the structural level, the most productive patterns of verbal phrases and nominal compounds are being presented. Special attention is devoted to various types of verb-based nominal phrases which refer to perceiving the surrounding world through instances of people’s behavior. The structural phraseologisms are also seen as a means of abstract conceptualization and a source of grammaticalization processes. The cultural background of the Hausa phraseologisms is referred to culture key-words and the traces of cultural experience which determine the meaning of the whole phrase. This approach includes a comparative perspective in studies on phrasal expressions in the Hausa language. The examples are taken from lexicographic sources and from descriptive works, they are also extracted from literary texts, the text of “Magana Jari Ce” [Speech is an Asset] by Abubakar Imam in particular.
Centros de escucha en Colombia : políticas y escenarios para la reducción de daños en comunidades locales
Authors: Góngora Andrés , Salazar Johanna , Borja Ramiro
Published: May 2021

Apresenta as transformações e a implementação de um modelo para intervir em situações de sofrimento social (incluindo o uso problemático de drogas), denominado Epistemologia da Complexidade Ética e Comunitária (ECO2) e para uma de suas derivações, o Tratamento com Base na Comunidade (CBT).
Approximations of the Spin of Close Black Hole–Wolf–Rayet Binaries
Authors: Bavera Simone S. , Zevin Michael , Fragos Tassos
Published: May 2021

Population synthesis studies of binary black hole mergers often lack robust black hole spin estimates as they cannot accurately follow tidal spin-up during the late black hole–Wolf–Rayet evolutionary phase. We provide an analytical approximation of the dimensionless second-born black hole spin given the binary orbital period and Wolf–Rayet stellar mass at helium depletion or carbon depletion. These approximations are obtained from fitting a sample of around 105 detailed MESA simulations that follow the evolution and spin up of close black hole–Wolf–Rayet systems with metallicities in the range

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. Following the potential spin up of the Wolf–Rayet progenitor, the second-born black hole spin is calculated using up-to-date core collapse prescriptions that account for any potential disk formation in the collapsing Wolf–Rayet star. The fits for second-born black hole spin provided in this work can be readily applied to any astrophysical modeling that relies on rapid population synthesis, and will be useful for the interpretation of gravitational-wave sources using such models.
An interactive online IT tool to aim the environmental surveillance of veterinary antibiotics in agriculture and pasture lands
Authors: Rodríguez Antonio , de la Torre Ana
Published: May 2021

The undermining of the therapeutic effectiveness of antibiotics by their widespread use is causing the emergence of antimicrobial resistance, which is a major threat for both animal and human health. Since most veterinary antibiotics employed in livestock production are excreted essentially unaltered, they have been identified as major contributors of environmental contamination. However, the efforts of monitoring antimicrobial effects are focused on humans and livestock, neglecting the environment. The European Union institutions recognized this gap in the appreciation of the issue, and adopted an approach that includes to prioritize environmental tracking and to build the tools to make it economically accessible. This abstract has three main targets. Firstly, to fill the gap applying the IT methodological approach (the soil vulnerability map to antibiotic contamination) developed by De La Torre et al. (2012). Secondly, to identify the main livestock species and scenarios (agriculture and pasture) to be prioritized in surveillance efforts. Finally, to implement the code of agriculture practices and the stocking rates of grazing animals based on high vulnerability areas for antibiotic contamination. To facilitate the implementation of this risk evaluation procedure, we developed an interactive tool that allows to obtain downloadable maps of soil vulnerability to contamination for several land use (agriculture and pasture) and livestock (cattle, pig and chicken) scenarios for any veterinary antibiotics. Additionally, the tool allows to obtain a plot of the mean vulnerability of each considered administrative unit. We implemented the European Union countries as an example, but the tool could be applied to individual countries or even regional or sub-national scales.
Sykdomspulsen One Health - A real time surveillance system in an infrastructure coping with half a million analysis a day
Authors: Koren Clemence , Swanson David , Grøneng Gry , Rø Gunnar , Hopp Petter , Jonsson Malin , White Richard
Published: May 2021

Sykdomspulsen is a real time surveillance system developed by the Norwegian Institute of Public Health (NIPH) for One Health surveillance and the surveillance of other infectious diseases in humans like respiratory diseases and lately covid-19.

The One Health surveillance comprise of Campylobacter data from humans and chicken farms and also includes diagnosis codes from doctor appointments and weather data with analysis forecasting outbreaks in Norway. It is a joint project between the Norwegian Institute of Public Health (NIPH) and the Norwegian Veterinary Institute (NVI), under the framework of the OHEJP NOVA (Novel approaches for design and evaluation of cost-effective surveillance across the food chain) and MATRIX (Connecting dimensions in One-Health surveillance) projects.

The system relies on two pillars, the first being an analytics infrastructure which in real time retrieves data from tens of sources, cleans and harmonizes it, then runs over half a million analyses each day and produces over 20 000 000 rows of results to be used every day. The analytics infrastructure is based on R. Results are notably being used by NIPH for the monitoring of covid-19 development and the surveillance of other transmittable diseases such as influenza and gastro-intestinal illness. The analytics framework also generates hundreds of reports every day, directed at dissemination to municipal health authorities. This framework is not currently publicly available, but an open-source release is expected by the end of 2021.

The second pilar is an interactive R Shiny dashboard platform, which is used for communicating the data and the model results to partner organisations. It allows for the easy creation of a website where public and animal health researchers and food safety experts can view real time analyses. This dashboard combines the powerful data visualisation and analysis strength of R with the accessibility, flexibility, structure and interactivity of web-based platforms.

The result is a real time interactive surveillance system, that is supported by a solid infrastructure and streamlined data flow, and shared with actors through a beautiful and user-friendly website, based entirely on R.
Food products identified as source of a foodborne disease outbreak by a fast and robust likelihood estimation
Authors: Fusiak Jakub , Kausrud Kyrre , Gottschald Marion , Tölle Dominic , Rügen Marco , Lewicki Birgit , Gerber Isaak , Kayser Michele , Falenski Alexander , Weiser Armin , Jore Solveig , Norström Madelaine , Alt Katja
Published: May 2021

Identifying a specific product causing a foodborne disease outbreak can be difficult, especially when dealing with a large amounts of suspicious food items and weak epidemiological evidence. A previously described likelihood model (Norström et al. 2015), improved within the OHEJP NOVA project, helps to prioritize food products that should be sampled for laboratory analysis. It is the aim of our study to integrate this approach into state of the art tracing software FoodChain-Lab (FCL; https://foodrisklabs.bfr.bund.de/foodchain-lab) developed at BfR to facilitate outbreak investigations.

The model improved by Kausrud et al. in R (Ihaka and Gentleman 1996) uses wholesale data, the distribution of disease cases and census data to sort food items by their estimated likelihood to be the source of an outbreak. We developed a fast and secure intuitive software module using the Web Assembly technology (Haas et al. 2017) allowing professionals to embed the module easily into other applications.

We integrated the module into the FCL web application for tracing (FCL Web; https://fcl-portal.bfr.berlin) to provide an intuitive and user-friendly solution. This solution combines a simple data input with extended data wrangling to make the calculation of the NOVA model as easy as possible. Since the model can be executed directly inside the web browser and therefore does not rely on any server environment, the possibility of data leakage can be highly reduced. The implementation of the advanced likelihood model into FCL Web increase the availability of this model and provides investigators easy, fast and reliable usage to improve outbreak investigation workflows.
First national record of Gracixalus quangi Rowley, Dau, Nguyen, Cao & Nguyen, 2011 and G. yunnanensis Yu, Li, Wang, Rao, Wu &Yang, 2019 (Amphibia: Anura: Rhacophoridae) from Thailand
Authors: Lorphengsy Sengvilay , Nguyen Tan , Poyarkov Nikolay , Wu Yun-He , Pawangkhanant Parinya , Passorn Supaporn , Che Jing , Suwannapoom Chatmongkon
Published: May 2021

The bushfrog genus Gracixalus Delorme, Dubois, Grosjean & Ohler, 2005 is found in southern and south-western China, Vietnam, Laos, Thailand and Myanmar. It is presently comprised of 17 species. In Thailand, only two species have been recorded, namely G. carinensis (Boulenger) and G. seesom (Massui, Khonsue, Panha & Eto). The latter of these two species is currently known to be endemic to the country.

Based on recent field work conducted in 2019 in Doi Phu Kha National Park, Nan Province of northern Thailand, we are reporting two new records of the genus Gracixalus, G. quangi and G. yunnanensis, from Thailand, based on morphological and molecular evidence. In addition, this is the first study to report on the identification of a female specimen of G. yunnanensis. Furthermore, morphological data and natural history notes of the aforementioned species in Thailand have been provided, along with updated locations for the distribution of both species.
Taxonomic reassessment and phylogenetic placement of Cyrtodactylus phuketensis (Reptilia, Gekkonidae) based on morphological and molecular evidence
Authors: Termprayoon Korkhwan , Rujirawan Attapol , Grismer L. Lee , Wood Jr. Perry L. , Aowphol Anchalee
Published: May 2021

The taxonomy and phylogeny of the Cyrtodactylus pulchellus complex along the Thai-Malay Peninsular region has been the focus of many recent studies and has resulted in the recognition of 17 species. However, the majority of these studies were focused on Peninsular and insular Malaysia where there were specimens and genetic vouchers. The taxonomic status and phylogenetic relationships of the Thai species in this complex remain unresolved, due to the lack of genetic material of some species, especially C. phuketensis and C. macrotuberculatus from Thai populations. In this study, we investigated the phylogenetic relationship between C. phuketensis and its closely related species C. macrotuberculatus, using both morphometric and molecular data. Phylogenetic analyses of mitochondrial NADH dehydrogenase subunit 2 (ND2) gene revealed that C. phuketensis is embedded within a C. macrotuberculatus clade with 1.45–4.20% (mean 2.63%) uncorrected pairwise sequence divergences. Morphological comparisons showed nearly identical measurements of C. phuketensis and C. macrotuberculatus and overlapping ranges in meristic characters. Based on these data, C. phuketensis is considered to be a variant of C. macrotuberculatus, thus rendering C. phuketensis a junior synonym of C. macrotuberculatus.
Creating a Work Environment Conducive to Organizational Learning
Authors: Lyman Bret , Biddulph Marisa E. , Hopper V. Grace , Horton Morgan K. , Mendon Camille R. , Thorum Kylie C. , Smith Emily L.
Published: May 2021

Through organizational learning, health care teams can consistently provide excellent patient care in a complex and changing environment. Nurse managers, educators, and other leaders can facilitate organizational learning within their teams by promoting certain contextual factors in the clinical work environment. This article provides an overview of contextual factors associated with organizational learning, includes practice-based examples of these factors, and offers evidence-based recommendations for creating a learning-focused work environment.

[
J Contin Educ Nurs
. 2021;52(6):281–285.]
Smart Glasses Implementation in Hospitals
Authors: Gong XiaoXue , Wong Ann Hung , Darobovna Rashidova Kamilla , P. S. JosephNg
Published: May 2021

Wearable Smart Glasses visualises information projected onto the lens, col-lects data over a wireless network, and uses a program to convert it into text or images to be transmitted to the display. This study discovers the usage of the products that will serve the medical industry, and as a result to design differ-ent products according to different uses, so to customize different prices and willingness of the targeted industry and people to purchase while meet the needs of more consumers. Therefore, the feasibility of using smart glasses in surgery was studied in this study, a technology acceptance model was used to analyze people's acceptance of the use of smart glasses in medical system. Mix mode analysis of the data was conducted through the explanatory study and the cross-sectional study, and relevant data were collected using an online questionnaire. The study found that surgeons using smart glasses could im-prove the success rate of surgery.
A Greedy Clustering Algorithm for Multiple Sequence Alignment
Authors: Lebsir Rabah , Layeb Abdesslem , Fariza Tahi
Published: May 2021

This paper presents a strategy to tackle the Multiple Sequence Alignment (MSA) problem, which is one of the most important tasks in the biological sequence analysis. Its role is to align the sequences in their entirety to derive relationships and common characteristics between a set of protein or nucleotide sequences. The MSA problem was proved to be an NP-Hard problem. The proposed strategy incorporates a new idea based on the well-known divide and conquer paradigm. This paper presents a novel method of clustering sequences as a preliminary step to improve the final alignment; this decomposition can be used as an optimization procedure with any MSA aligner to explore promising alignments of the search space. In their solution, authors proposed to align the clusters in a parallel and distributed way in order to benefit from parallel architectures. The strategy was tested using classical benchmarks like BAliBASE, Sabre, Prefab4 and Oxm, and the experimental results show that it gives good results by comparing to the other aligners.
Vector backbone integration in transgenic cassava is significantly correlated to T-DNA copy number
Authors: Okwuonu I.C. , Egesi C.N. , Taylor Nigel James
Published: May 2021

Multiple T-DNA integrations often occur with transgenic technology, resulting in complex integration patterns and transgene silencing. This study, investigates the correlation coefficient of T-DNA copy number on vector backbone (VBB) integration in transgenic cassava using Dot blot and PCR analysis. Thirty-nine, fifty-one and thirty-eight transgenic cassava plant lines recovered from transformations of cassava friable embryogenic callus with A. tumefaciens strain LBA4404 independently carrying p8016, p8052, and p900 were randomly selected and evaluated for VBB integration and T-DNA copy number. The occurrences of events with low (1-2) and high (≥ 3) T-DNA copy numbers were correlated with the presence and absence of VBB integration. Seventy-two to ninety-eight percent of VBB-free events were low copy number events while 2 to 28% of same where high copy number events. Correlation coefficient of the data revealed that the number of VBB-free events showed a significant positive correlation (r = 0.821, n = 9, p = 0.01) for events with low T-DNA copy number and a significant negative correlation (r = -0.739, n =9, p = 0.02) for high copy number events. This shows that the recovery of events with low T-DNA copy number increases the chances of recovering VBB-free events thereby enhancing the production of quality transgenic events.

Key words: Copy number, DsRed, T-DNA, transformation, transgenic cassava, vector backbone integration.
Antisickling Activities of Some Nigerian Medicinal Plants
Authors: Fatokun OT , Agbedahunsi JM , Elujoba AA
Published: May 2021

Sickle cell anaemia (SCA) is a genetic condition caused by defective haemoglobin molecules. Symptoms are often associated with painful crisis often accompanied with vaso-occlusion, severe anaemia, acute chest syndrome, stroke, multiple organ failure, etc. In the pursuit of searching for suitable and affordable anti-sickling herbal remedies, aqueous and ethanolic extracts of ten medicinal plants from relevant previous ethnomedical records, were screened using standard methods involving whole HbSS blood and found to possess varying degrees of anti-sickling activities. For example, Anthocleista vogelii Planch (Gentiaceae) gave 12% inhibitory and 61% reversal activities; Cassia sieberiana DC ripe fruit and pericarp (Leguminoseae) gave 54% inhibitory, 90% reversal activities and 71% inhibitory and 54% reversal activities, Harungana madagascariensis Lam. ex. Poir (Hypericaceae) gave 42% inhibitory and 52% reversal activities and Senna alata (L.) Roxb. (Leguminoseae) gave 19% inhibitory and 84% reversal activities. Thus, the pericarp and whole fruit extracts of Cassia sieberiana pericarp gave the best inhibitory activity (71%) and reversal (90%) activities respectively while S. alata appeared to be a competing candidate for reversal activity (84%). Consequently, an appropriate herbal combination research on the three plant materials to achieve the best inhibitory and reversal activities in a single formulation is in progress.Keywords: Anti-sickling, Cassia sieberiana, Senna alata
Inhibitory Effect of Garcinia kola Heckel (Clusiacea) Seed Extracts on Some Key Enzymes Linked to Diabetes Mellitus
Authors: Zakariya AM , Danmalam UH , Sallau AB , Ibrahim G , Hassan SM
Published: May 2021

Enzymes linked with diabetes mellitus and Phytochemical characterization of its bioactive constituents. Crude n-hexane, ethyl acetate and methanol extracts were prepared successively in a soxhlet apparatus at 50ºC. Subsequently, extraction of crude enzymes from porcine pancreas and rat intestine, thin layer chromatographic analysis (TLC), and inhibitory effects of the extracts on b-amylase and b-glucosidase were determined in vitro. The results reveal that G. kola seed extracts inhibited b-amylase (IC50=  4.89 mg/ml, 3.44 mg/ml, 0.78 mg/ml) and b-glucosidase (IC50= 10.29 mg/ml, 1.68 mg/ml, 2.67 mg/ ml) corresponding to n-hexane, ethyl acetate, methanol gradient extracts. n-hexane extract had the highest inhibitory effect on b-amylase, while methanol extract was highest on b-glucosidase. Characterization of the bioactive constituents of the extracts using TLC analysis revealed the presence of steroids/triterpenes and phenolic compounds with phenolic compounds appearing in all extracts irrespective of the solvent polarity used for extraction. Anthraquinone and alkaloids were confirmed absent on TLC. This enzyme inhibition could be one of the possible pathways by which G. kola elicits its antidiabetic properties. Furthermore, the enzyme inhibitory properties of the extracts can be attributed to the presence of steroids/triterpenes, phenolic compounds in the seeds of G. kola.Keywords: Garcinia kola, b-amylase, b-glucosidase, TLC, Inhibitory Effect
Distribution of generalized mex-related integer partitions
Authors: Chakraborty Kalyan , Ray Chiranjit
Published: May 2021

The minimal excludant or "mex" function for an integer partition π of a positive integer n, mex(π), is the smallest positive integer that is not a part of π. Andrews and Newman introduced σmex(n) to be the sum of mex(π) taken over all partitions π of n. Ballantine and Merca generalized this combinatorial interpretation to σrmex(n), as the sum of least r-gaps in all partitions of n. In this article, we study the arithmetic density of σ_2 mex(n) and σ_3 mex(n) modulo 2^k for any positive integer k.
(q-)Supercongruences hit again
Authors: Zudilin Wadim
Published: May 2021

Using an intrinsic q-hypergeometric strategy, we generalise Dwork-type congruences H(p^{s+1})/H(p^s) ≡ H(p^s)/H(p^{s−1}) (mod p 3) for s = 1, 2,. .. and p a prime, when H(N) are truncated hypergeometric sums corresponding to the periods of rigid Calabi-Yau threefolds.
Ramanujan's Beautiful Integrals
Authors: Berndt Bruce , Dixit Atul
Published: May 2021

Throughout his entire mathematical life, Ramanujan loved to evaluate definite integrals. One can find them in his problems submitted to the Journal of the Indian Mathematical Society, notebooks, Quarterly Reports to the University of Madras, letters to Hardy, published papers and the Lost Notebook. His evaluations are often surprising, beautiful, elegant, and useful in other mathematical contexts. He also discovered general methods for evaluating and approximating integrals. A survey of Ramanujan's contributions to the evaluation of integrals is given, with examples provided from each of the above-mentioned sources.
One level density of low-lying zeros of quadratic Hecke L-functions to prime moduli
Authors: Gao Peng , Zhao Liangyi
Published: May 2021

In this paper, we study the one level density of low-lying zeros of a family of quadratic Hecke L-functions to prime moduli over the Gaussian field under the generalized Riemann hypothesis (GRH) and the ratios conjecture. As a corollary, we deduce that at least 75% of the members of this family do not vanish at the central point under GRH.
Computational analysis of incremental clustering approaches for Large Data
Authors: Kushwah Arun Pratap Singh , Jaloree Shailesh , Thakur Ramjeevan Singh
Published: May 2021

Clustering is an approach of data mining, which helps us to find the underlying hidden structure in the dataset. K-means is a clustering method which usages distance functions to find the similarities or dissimilarities between the instances. DBSCAN is a clustering algorithm, which discovers the arbitrary shapes & sizes of clusters from huge volume of using spatial density method. These two approaches of clustering are the classical methods for efficient clustering but underperform when the data is updated frequently in the databases so, the incremental or gradual clustering approaches are always preferred in this environment. In this paper, an incremental approach for clustering is introduced using K-means and DBSCAN to handle the new datasets dynamically updated in the database in an interval.