bluuebunny/crossref_metadata_2025 huggingface dataset:
How Does Consumer Experience with Cosmetics Products Create EWOM, Satisfaction, and Loyalty?
Authors: Fatmawati Indah , Amanati Annisa Khoirul
Published: March 2023

Research aims: This study investigates how consumer experience with local beauty products influences Electronic Word of Mouth (EWOM), satisfaction, and loyalty.Design/Methodology/Approach: The researchers employed a quantitative approach with an explanatory survey design. The setting was a local medium, low-end beauty product in Indonesia that competes with many global brands. The respondents were 160 women who recently purchased, used the brand, and performed EWOM. The researchers used online questionnaires to collect data distributed via Google forms. The proposed hypotheses were then tested using Structural Equation Modeling (SEM) with the AMOS version 22.0 application. Research findings: This study found that (1) experiential marketing had a positive impact on customer satisfaction, EWOM, and customer loyalty; (2) customer satisfaction and EWOM also positively impacted customer loyalty; (3) while customer satisfaction mediated the effect of experiential marketing on customer loyalty, (4) EWOM mediated the experiential marketing effect on customer loyalty.Theoretical contribution/Originality: This study improved people’s understanding of the importance of creating costumers experience, which contributed to their satisfaction and willingness to perform EWOM, despite its direct influence on customer loyalty. This study also gives insight into customer satisfaction and willingness to perform EWOM, which will shape their loyalty to the product. The researchers further highlight the existence of customer satisfaction and EWOM in forming customer loyalty since those two constructs significantly mediate the relationship between experiential marketing and customer loyalty.Practitioner/Policy implication: The marketer needs to create a good customer experience, shaping customers’ satisfaction and influencing them to perform Electronic Word of Mouth. Furthermore, satisfied customers and those who already make an EWOM will create customer loyalty.Research limitation/Implication: The researchers identified three limitations and proposed suggestions for future study. First, the researchers used limited respondents, which may influence the generalization of this research’s findings. Increasing the sample size may improve the research findings' generalizability. Second, most respondents' backgrounds were also limited to university students, while getting more varied respondents may give different results. Finally, since the researchers only considered four variables in this research model, the researchers proposed that future research should consider additional variables to explain this phenomenon better.
A study of fine needle aspiration cytology findings with thyroid function test, anti-thyroid antibody, and clinical pathological parameters in cases of chronic lymphocytic thyroiditis
Authors: Marachapu Jahnavi , Vij Swati
Published: March 2023

: Chronic lymphocytic thyroiditis is autoimmune thyroiditis; it is considered as second most common thyroid disorder diagnosed on FNAC following colloid goitre. FNAC is a reliable and efficient method for diagnosing these thyroid lesions. Chronic Lymphocytic thyroiditis frequently affects women, primarily compared to men and is commonly found with hypothyroidism, euthyroidism or every so often with hyperthyroidism. The incidence rate of Hashimoto’s thyroiditis is 1–4%, with an occurrence of 30–60/100000 population per year. Autoimmune thyroiditis can be categorised on the cytomorphological features of FNAC.

To compare FNAC cytological findings with TFT in Chronic lymphocytic thyroiditis. One hundred ten patients with thyroid swellings were presented for FNAC examination, serology of TFT and Anti TPO antibodies and Ultrasonography during 2020–2021. In addition, fine needle aspiration cytology was performed using non-aspiration or aspiration techniques. TFT and Anti- TPO antibodies were performed on Avion CLX 120 auto analyser based on the Chemiluminescence method.

Out of 110 cases of midline neck swelling presented in our department, Autoimmune Thyroiditis was observed in 43 cases. The most affected age group of lymphocytic thyroiditis was 21–30 years, with the male: female ratio being 1:3. Most of the patients presented with diffuse swelling and few presented with nodular swelling. The Grading of the lymphocytic thyroiditis was done by the criteria used by Bhatia et al Anti-TPO antibody was elevated in 19 cases (26.2%), and TSH was elevated in 28 cases (40.81%). These cases were diagnosed as autoimmune thyroiditis on cytology, clinically and also correlating with radiological findings. Grade 3 lymphoid infiltrate was seen in 53.33% (16/30) cases, and Grade 2, lymphoid infiltrate was seen in eight cases (62.50%). Grade 1 lymphoid infiltrate was seen in five cases (11.63%). Among 43 cases, 28 cases (65.12%) show hypothyroidism, 7 cases (16.28%) show hyper, and 8 cases (18.60%) show Euthyroidism. Among these 43 cases, 26 cases showed diffuse thyroid swelling on ultrasonography, and 7 cases showed solitary nodule.

Grade 3 lymphocytic infiltration statistically correlates with anti-TPO and TSH in conjunction with ultrasonography findings of diffuse enlargement of the thyroid gland. The presence of Hurthle cell change, giant cells, anisonucleosus, and granulomas do not find to be any statistical correlation with lymphocytic thyroiditis as these cases are primarily corresponding to Grade 1 and Grade 2. Through this study, we conclude that FNAC remains the gold standard method despite having different diagnostic modalities accessible for diagnosing thyroid lesions. Grading of FNAC Smears depends on lymphocytic infiltration of the thyroid follicles, along with positivity for antithyroid antibodies (anti-TPO antibody) and TSH. These findings are firmly associated with Chronic Lymphocytic Thyroiditis.
Accuracy of different cytoarchitectural features in the diagnosis of papillary thyroid carcinoma by fine needle aspiration
Authors: Malhasi I W G A L , Fernando C S , de Silva MVC
Published: March 2023

Fine needle aspiration (FNA) has about 90% diagnostic accuracy for papillary thyroid carcinoma (PTC) in an adequate sample. Ignorance of relative significance of individual cytologic features may lead to misdiagnosis due to reliance on a single or few features. Our objective was to determine the usefulness of individual and most appropriate combined cytologic features, for diagnosis of PTC.

H&E stained FNA smears of fifty cases each, of consecutive histologically confirmed PTC and benign thyroid cases (controls), reported over 3 years, were retrieved from the files. A total of 31 architectural, cytological and background features were assessed, blind to the final diagnosis and compared amongst the two groups. The statistical significance (p<0.05) of each parameter was determined by chi-square and odds ratio and combinations quality assessed by ROC curves.

: Twenty features were found to be statistically significant. Fourteen highly significant (p<0.000) features included flat syncytial sheets, anatomical borders, true papillae, cellular swirls, individually dispersed cells with eosinophilic cytoplasm, anisonucleosis, elongated oval nuclei, powdery chromatin, nuclear outline irregularity, thickened nuclear membranes, crescent shaped nuclei, intranuclear inclusions, histocytoid cells and soap bubble cytoplasmic vacuolation. The six statistically significant features (p<0.05) included micro-acinar structures, cellular crowding, nuclear overlapping, nuclear grooves, squamoid cells and bubble gum colloid. The control group also showed some of these single cytologic features. All the combinations of ≥ 4 features had a statistical significance of p=0.000 and specificity and PPV of 100% with ROC showing excellent results.

Using correct combination of cytologic features will increase accuracy of FNA diagnosis of PTC.
High prevalance of triple negative markers in breast cancer patients in North Maharashtra
Authors: Agrawal Sakshi , Jadhav Nilesh , Dravid Nandkumar V , Kaderi Arif , Newadkar Dhananjay , Gadre Arundhati
Published: March 2023

Breast cancer is the most prevalent cancer among women worldwide. The Bloom Richardson grading has been applied to most breast cancers. There are different biologic subtypes of breast cancer according to immunohistochemistry (IHC). Clinically, these subtypes are characterized on the basis of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). Among them, Triple Negative Breast Cancer (TNBC) which lacks expression of the ER, PR, and HER-2-neu, is most aggressive form. TNBC cases have worse prognosis, require aggressive chemotherapy and are difficult to manage. The advent of neoadjuvant chemotherapy has highlighted the importance of IHC, Breast Ca and TNBC. The aim and objective of this study is to find prevalence of TNBC in Breast Cancer patients in North Maharashtra. This is a 3- Year ambiceptive analysis done to study the incidence of TNBC among Breast Cancer cases. Out of 58 Breast Cancer cases diagnosed in our institute, 30 cases in which IHC was done were included in this study. Postmortem breast cancer cases, core needle biopsies and mastectomies in which IHC was not done were excluded. Among 30 cases studied, 53.33% cases were TNBC, 23.33% cases were ER and PR positive, 10% cases were only HER-2-neu positive, 6.66% cases were only ER positive, 3.33% cases were only PR positive, and 3.33% cases were all three ER, PR and HER-2 neu positive. To conclude, India has considerably higher prevalence of TNBC, as compared to the Western countries. This finding has significant clinical relevance as it may have contributed to poor outcomes in patients with breast cancer in India. With advent of neoadjuvant chemotherapy, use of Modified Bloom- Richardson Grading & IHC is of crucial importance. To understand the determinants of TNBC in India additional research is needed for diagnosis and treatment follow-up.
Histopathological findings of enucleated specimen of eye in children - A case series of 4 cases
Authors: Barman Manoj , Aziz Naima , Devi Junu
Published: March 2023

Retinoblastoma is one of the common intraocular malignancy in childhood. It’s incidence varies between 1 in 3300 to1 in 20,000 live birth. Retinal dysplasia is a rare disorder which can mimic retinoblastoma. Retinal dysplasia is a rare cause of childhood leucocoria, which can cause considerable diagnostic difficulty in the differentiation of benign and malignant intraocular pathologies Enucleation is often required for both these conditions. In this series we are discussing 4 cases of enucleated eyeball. Out of these 4 cases three cases were of retinoblastoma.4 case was done for post traumatic phthysis bulbi. In this case series we are discussing diagnostic and prognostic indicators of Retinoblastoma as well as retinal dysplasia.
An unexpected finding of bone marrow metastasis from adenocarcinoma of lower gastrointestinal tract origin: Case report
Authors: Sharma Saket , Makwana Jhanvi , Kaka Riya , Mandal Moushumi
Published: March 2023

Bone marrow examination is an essential tool for diagnosis of many diseases including both hematological and non hematological tumors. Bone marrow is commonly involved by many metastatic solid tumors. Bone marrow aspirates, and biopsies have been found to be more useful than radiological investigations in early diagnosis of bone marrow metastasis.

Here we present a case of a 75 years old male patient presenting with acute sudden onset chest pain along with multiple lytic sclerotic foci in lumbar vertebrae, bilateral ribs, clavicle, scapula and sternum along with fractures in multiple ribs. CBC findings showed anemia with thrombocytopenia. Bone marrow examination revealed an infiltration of a metastatic tumor in bone marrow which was further confirmed to be of lower gastrointestinal tract in origin on IHC findings.

A high suspicion for bone marrow metastasis should be considered in cases who present primarily with abnormalities in peripheral blood count and a vigilant search for metastatic cells on aspirate smears and imprint smears can help in early diagnosis of bone marrow metastasis by solid tumors.
Cytodiagnosis of multilobulated aggressive angiomyxoma clinically mimicking sarcoma – A case report
Authors: Phukan Neeharika , Devi Junu
Published: March 2023

: Aggressive angiomyxoma is a rare but locally aggressive infiltrative mesenchymal tumour arising in the soft tissues of the lower genital tract. Incidence is very less (only about 350 cases have been recorded in the literature) with female to male ratio of 6:1. Average age at presentation is around 40 years.

: A 32 years old female presented with multiple swelling in the vulval region for 1 and a half years associated with mild pain. The patient complains of dysmenorrhoea, pressure sensation, pelvic fullness, dyspepsia, weight loss and generalised weakness. She is married and has a 3-year old male child. Her menstrual cycle is regular with normal menses. FNAC of the vulval swelling was suggestive of angiomyxoma. The swelling was excised in the Gynaecological Operation Theatre and the specimen was sent to the Department of Pathology for Histopathological examination where it was diagnosed as aggressive angiomyxoma. On follow up, the patient was healthy with no complains of recurrence so far.

: Aggressive angiomyxoma is an aggressive tumour because it has a high risk of infiltration and local recurrence. Therefore, it should be distinguished from other myxoid tumours. Preoperative cytological diagnosis helps in surgical management with appropriate wide local excision with clear margins.
Giant retroperitoneal dedifferentiated liposarcoma - A rare case report
Authors: Palaniraj S , Gopu G , Jayanthi Bharathi Vidhya
Published: March 2023

Retroperitoneal liposarcomas are uncommon malignancy accounting for 0.15% of all malignancies. The overall survival and prognosis is predominantly based on the total completeness of resection i.e. margin status and the histopathologic grade of the tumour.

The retroperitoneal sarcomas usually present late in the disease course and often develops local invasion of the vital structures at the time of clinical presentation which makes resection with clear margins difficult and challenging. Here we present a case of Giant dedifferentiated liposarcoma arising from retroperitoneum.
Myoid hamartoma of breast clinically masquadering as phyllodes tumor- A rare case report
Authors: Varma Kachnar , Tripathi Sonal , Sharma Neha , Misra Vatsala
Published: March 2023

Mammary hamartoma (MH) is an infrequent form of breast tumor that accounts for approximately 4.8% of all benign breast lesions. Myoid (muscular) hamartomas are uncommon benign breast lesions that are considered to be a variant of mammary hamartomas. Since the pathogenesis of MH is poorly understood, its true incidence is under-reported by clinicians and as well as pathologists.

Thus, we report this case of MH in a middle-aged female, who presented with a large breast mass mimicking phyllodes tumor and giant fibroadenoma, however, histopathology and immunohistochemical examination aided its diagnosis as Myoid Hamartoma. We present this case to highlight this rare benign breast lesion.
Acrokeratosis verruciformis of Hopf: A rare case report
Authors: Mohanty Shushruta , Panda Sujata , Sahu Deepika , Padhi Shilpa
Published: March 2023

Acrokeratosis verruciformis of Hopf (AKV) is a rare cutaneous autosomal dominant genodermatosis described by Hopf in 1931. It usually presents at birth or may appear as late as 5 decade of life. It is characterized by multiple hyperkeratotic, verrucous papules/plaques to multiple planar wart like lesions on dorsal aspects of hand and feet. Due to rarity of the case, we present a case of AKV in a 60-year-old male that was diagnosed on histopathology. We the authors have attempted to describe the histological features of AKV with differential diagnosis of these lesions through review of literature.
“¿Qué opción les queda a las personas, más que nosotros?”: Las funciones de los consultorios adyacentes a farmacias en la pandemia de covid-19
Authors: Morán Pérez Ana Victoria
Published: March 2023

Con la llegada del coronavirus a México, los consultorios adyacentes a farmacias desempeñaron un rol preponderante en el diagnóstico, atención y prevención del covid-19. De acuerdo a las encuestas nacionales, entre el 11,7% y el 23% de las personas con síntomas de covid-19 se atendieron en uno. Por ello, este artículo busca identificar el papel de los consultorios adyacentes a farmacias (CAF) como sistema de salud privado que atendió a personas con síntomas de covid-19 en la ciudad de Oaxaca y describir y analizar los factores que influyeron en su utilización. Desde una metodología cualitativa, entre septiembre de 2020 y agosto de 2022 se entrevistó a 12 médicos y médicas y se aplicó un cuestionario a 59 personas usuarias de los consultorios adyacentes a farmacias del municipio de Oaxaca de Juárez. Asimismo se hizo una recopilación y análisis de fuentes secundarias. Entre los hallazgos, se describen sus funciones como frente de atención al covid-19 y a otras necesidades de salud que emergieron con la crisis sanitaria y se analizan los factores determinantes en las trayectorias de atención de personas usuarias de estos consultorios, como son el incremento en la percepción del riesgo y la desconfianza hacia los servicios públicos o hacia las estrategias implementadas por el gobierno federal.
Proposta de Construtos da Intenção Empreendedora: um estudo a partir da teoria do comportamento planejado
Authors: Primo Vanessa De Fátima Silva , Lima de Sousa Kassyo Augusto , Fonseca e Fonseca Paulo Roberto Campelo
Published: March 2023

O curso de administração por intermédio da sua matriz curricular, que visa gerar competências e habilidades de gestão nos seus egressos, dentre elas, a de empreender, pode gerar uma motivação ou intenção empreendedora, que se traduz no comportamento dos egressos orientado para a abertura de negócios. Dessa forma, o objetivo deste estudo é levantar quais são os preditores da intenção empreendedora de acadêmicos de Administração de uma IES privada em São Luís do Maranhão de acordo com a Teoria do Comportamento Planejado, uma derivação da Teoria da Ação Racional. Para alcançar esse objetivo, foi feito um estudo de caso em uma IES privada onde participaram 101 estudantes do 1º ao 8º período do curso de Administração. Para as análises estatísticas deste artigo utilizou-se o software IBM SPSS Statistics, sendo realizados os cálculos de frequência relativa e o teste de correlação entre as variáveis com a indicação do p-valor para identificação da significância estatística. Os resultados indicam que a variável motivacional (motivos de engajamento, carreira empreendedora, norma subjetiva e ambiente universitário) se relaciona mais fortemente com a intenção empreendedora, ou seja, quanto mais positivo são os motivos dos estudantes em relação ao empreendedorismo, mais forte é a sua intenção de seguir essa carreira.
Interlocuções teóricas entre empreendedorismo, carreira e aprendizagem
Authors: Dal Molin Wissmann Alexandre , Quadrado Closs Lisiane , Ribeiro da Luz Amanda
Published: March 2023

Este ensaio teórico tem como objetivo realizar uma interlocução entre os quadros conceituais de empreendedorismo, carreira e aprendizagem, buscando elementos de contribuição para o estudo da aprendizagem nas construções de carreira de pessoas que possuem suas atividades de trabalho ligadas ao empreendedorismo. Como resultado, por meio da elaboração de uma estrutura teórica, argumentamos que o estudo da aprendizagem a partir das construções de carreira consegue transpor domínios e dominações conceituais ao propor uma reunião entre os elementos de tempo, contexto, indivíduo, relações sociais, experiências e ferramentas, oferecendo uma estrutura flexível e hospitaleira para analisar as dinâmicas de aprendizagem ao longo da trajetória de vida do empreendedor. Por fim, como contribuição aos campos conceituais, entendemos que a estrutura teórica proposta possa ser utilizada como ponto de partida para estudos que tragam em suas bagagens, em conjunto ou de maneira individual, as noções de empreendedorismo, carreira ou aprendizagem.
Gestão e organização do estoque em empresas de varejo: um estudo comparativo de duas empresas de Loanda, Paraná
Authors: Holanda Briana Maria Souza , Santos Rejane Heloise dos , Santos William Alexandre dos
Published: March 2023

A área de gestão de estoques, ou administração de recursos materiais e patrimoniais é notória para a administração eficiente dos estoques materiais nas organizações. As atividades realizadas na administração de estoques têm papeis importantes quanto aos estoques e quanto ao fluxo financeiro de uma organização. Nesse sentido, o presente trabalho teve como objetivo compreender a gestão de estoque em duas empresas de varejo, do ramo da construção civil, da cidade de Loanda, estado do Paraná. Para tanto, elaborou-se uma pesquisa qualitativa e descritiva, com coleta de dados primários por meio de entrevistas semiestruturadas com duas empresas do ramo varejista de materiais de construção. A análise foi realizada utilizando-se da metodologia de análise de conteúdo. O resultado apresentou um quadro comparativo das duas organizações analisadas e observou, portanto, as semelhanças e diferenças entre as duas empresas, bem como a importância na utilização de ferramentas de controle na gestão de estoque em empresas que atuam na área comercial de vendas de produtos destinados à construção civil.
Práticas de Finanças Pessoais e o Nível de Satisfação dos Estudantes de Pós-Graduação Stricto Sensu em Ciências Contábeis no Brasil
Authors: Tibúrcio Machado Fabíola , Facin Lavarda Carlos Eduardo
Published: March 2023

O artigo teve como objetivo avaliar a relação das práticas de finanças pessoais com a satisfação com o curso dos estudantes de pós-graduação stricto sensu em Ciências Contábeis no Brasil. Os dados de 207 alunos das Universidades cadastradas na plataforma Sucupira em 2020 foram coletados por meio de questionário eletrônico entre os meses de março e maio de 2021. Os resultados mostram que a correlação de Spearman para dados categóricos entre as variáveis de finanças pessoais e satisfação com o curso mostrou-se fraca e não significante. O nível de concordância de satisfação com o curso apresentou média geral de 3,97 (escala 1 a 5). A satisfação dos alunos de pós-graduação não apresentou diferença nas variáveis bolsista, endividamento e planejamento, mas observou-se que os alunos com renda superior apresentaram maiores níveis de satisfação com o curso. O artigo apresenta contribuições teóricas, sociais e práticas. A contribuição teórica baseia-se na importância de expandir a abordagem do tema educação financeira, bem como da utilização de práticas de planejamento e orçamento financeiro pessoal. Com relação à contribuição social e prática, o estudo poderá auxiliar os estudantes com um melhor entendimento referente à gestão financeira pessoal, a adoção de novas práticas de planejamento e controle de suas finanças.
LEVEL OF MATH ANXIETY AMONG THE STUDENTS OF THE 5TH – 9TH YEAR OF STUDY IN SLOVAKIA
Authors: Janicek Pavelova Monika , Erhardtova Gabriela , Zovinec Erik
Published: March 2023

Mathematics accompanies us throughout our lives. Difficulties in acquiring mathematical ideas can appear even without the presence of a math learning disability – developmental dyscalculia. Our lack of success can result from various external or endogenous causes. People who have a higher level of math anxiety often have difficulties in everyday life, wherever mathematics occurs in some way. Therefore, it is important to pay attention to this issue and look for possible solutions and qualitatively discuss questions related to math anxiety. Why and what level of anxiety do individual mathematical tasks cause in some people? Is it not only the fear and anxiety of failure in mathematics but also of failure in everyday life in solving everyday problems, such as counting up purchases, planning financial transactions, interest, discounts, etc.? These difficulties cause fear, stress and anxiety in individuals, and the impairment of mathematical skills is transferred into adulthood. Chinn (2020) reports that up to 22% of adults in the UK have difficulties with the mathematics that limit them in everyday life. The paper is aimed at finding out the level of math anxiety in a selected population of students and analyzing the questionnaire "How I feel about math" Chinn (2020) translated into Slovak. The research group consisted of 11-16-year-old Slovak students. The aim of the paper is to point out the importance of investigating mathematics anxiety in the diagnosis of a mathematical learning disability. At the same time, to draw attention to the fact that students with special educational needs experience a higher level of math anxiety than their peers. The authors point out that there are no significant gender differences in the experience of math anxiety in the Slovak sample of students and confirm, as stated by Chinn, that 4-6% of neuro-typical (normal) children experience a high level of math anxiety.
Identity Generation with Deep Generative Models
Authors: Letizia Nunzio Alexandro
Published: March 2023

Deep generative models have drawn the attention of the AI community in the last decade. The scalability of neural architectures helps solving multiple relevant problems, e.g., text-to-image generation, otherwise not addressable. In the context of image data privacy, the increasing amount of produced, shared, and stored images imposes new measures to protect personal identity information. At the same time, such protection mechanisms need to preserve the image quality. In this talk, we discuss how PiktID is using some recent deep learning-based techniques for protecting human identities in pictures. We show several examples, and we present interesting use-cases.
Generiranje sintetičnih slik iz 3D modelov predmetov za učenje segmentacijskih modelov v industrijskem okolju
Authors: Fučka Matic , Rus Marko , Božič Jakob , Skočaj Danijel
Published: March 2023

Ena večjih preprek uporabe globokega učenja v industriji je zahteva po velikem številu označenih slik potrebnih za nadzorovano učenje. Ker je pridobivanje označenih slik pogosto zamuden in drag proces, se veliko metod skuša izogniti temu problemu z bogatenjem učnih slik, ki so na voljo, ali z uporabo sintetičnih slik za predhodno učenje in poznejše doučenje z resničnimi slikami. V tem članku predlagamo metodo za generiranje sintetičnih slik iz danih 3D CAD modelov in novo podatkovno množico sestavljeno iz sintetičnih in resničnih slik ter njihovih segmentacijskih slik. Obravnavamo torej scenarij učenja segmentacijskega modela zgolj iz sintetičnih slik, ki so v industriji tipično na voljo, in zagotavlja najhitrejšo prilagoditev proizvodnega procesa na nove izdelke brez potrebe po zajemanju pravih učnih slik. Na predlagani podatkovni množici ovrednotimo algoritem za segmentacijo slik in primerjamo rezultate dobljene z različnim številom sintetičnih in realnih slik industrijskega predmeta posnetega oz. upodobljenega na različnih ozadjih.
Effects of Cataract Surgery on Patient’s Quality of Life
Authors: Nanfack Ngoune Chantal , Kagmeni G , Nomo AF , William Nzokou , Noche C Donmgang , Assumpta Bella Lucienne
Published: March 2023

Background and Objective: Vision impairment caused by cataracts impacts patients’ daily activities, affecting their quality of life. This study aims to assess patients’ quality of life after cataract surgery using the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25). Method: Participants were patients who had undergone cataract surgery at Yaounde Gyneco-Obstetrics and Pediatrics Hospital (HGOPY) and Essos Medico-Surgical Center between September 1, 2018, and May 31, 2019. Participants were evaluated preoperatively, 14 days after cataract surgery, and one month after cataract surgery.
Peripapillary Subretinal Space of the Blunt Traumatic Optic Neuropathy: RPE/Bruch’s Membrane Complex Micro-Rips - The Novel SD-OCT Findings
Authors: Wang Fubin
Published: March 2023

Aim: To report the unusual SD-OCT findings in peripapillary subretinal space of the blunt traumatic optic neuropathy (TON). Methods: All patients underwent a comprehensive eye examination included color fundus photography, ultrasonography, fundus fluorescein angiography, visual field, PVEP if patient’s vision was allowed to examine. An orbital CT scan was performed for all of patients and no orbital fracture was found. However, we did not assess them here and assessed the results of SD-OCT examination only. Results: Peripapillary subretinal spaces of four contused eyes were abnormal that showed a flat, localized hyperreflection due to hemorrhages. It was adjacent to optic disc. The intensities of reflection could be nonuniform due to the blood concentration or contained serous liquid. It could be observed that RPE/Bruch’s membrane complex micro-rips, but ELM were normal that were not involved in the peripapillary subretinal space. Choroid rupture of macula was observed at times. Conclusion: For TON patients, to examine the peripapillary subretinal space by SD-OCT at first time might have valuable for diagnosis. The results suggested that the hemorrhages of peripapillary subretinal space might come from the peripapillary choriocapillaris.
Environmental factors that affect the incidence of stunting in under-five children: A literature review
Authors: Adi Sugiono , Krisnana Ilya , Rahmawati Praba Diyan , Maghfiroh Umi
Published: March 2023

Introduction: Stunting and other health issues affecting children under five result from unhealthy environments. Environmental sanitation by providing sanitary latrines and clean water supplies cannot be divorced from its influence. A review of the literature was conducted to assess how healthy latrines and clean water sources can improve stunting in children under the age of five.Methods: Four databases (Scopus, ProQuest, Science Direct, and Google Scholar) with high and medium-quality standards were used to find the articles for this literature study. The study’s quality was judged using Joanna B Institute’s criteria. The research is included in the inclusion criteria if it has a critical assessment score of at least 50%. PICOS used as the review’s organizing structure.Results: The availability of clean water sources and sanitary latrines significantly impacts stunting. Access to subpar latrines increases the risk of stunting in children under five. Stunting in children under five is influenced considerably by the availability of safe water sources.Keywords: environmental factors; stunting; under-five children
Antibacterial Activity of Mixed Infusion of Averrhoa bilimbi L. Fruit and Cananga odorata Flowers Against Several Numbers of Bacterial Colonies in Vitro Test
Authors: Budiarti Lia Yulia , Kaidah Siti , Adnia Nur , Sangadi Vania Puspitasari
Published: March 2023

Abstract: Antiseptic alcohol 70% is known to be effective in inhibiting the growth of bacterial colonization on the hands, but its use in the long term can cause skin disorders. An alternative antiseptic can be made from a mixture of star fruit (Averrhoa bilimbi L.) and flower Cananga (Cananga odorata) which contains several antibacterial compounds. The purpose of this study was to analyze the antibacterial activity of the infusion mixture of Averrhoa bilimbi and Cananga odorata flowers in inhibiting the growth of Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Salmonella typhi, and Shigella sonnei bacteria. This in vitro research design used a posttest only with control group design with the observation parameter being the number of test bacteria colonies that grew on the observation medium. The treatments tested were a mixture of 50%, 75%, and 100% Averrhoa bilimbi infusion and 100% Cananga odorata, and 70% alcohol control. The results showed that the infusion mixture of Averrhoa bilimbi and Cananga odorata had different inhibitory effects on Gram-positive and Gram-negative bacteria; the number of colonies of Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli was not significantly different from the mixed treatment concentration of 100% (1:1) with 70% alcohol treatment. In conclusion, the infusion mixture of Averrhoa bilimbi fruit and Cananga odorata flower had antibacterial activity against Gram-positive and Gram-negative bacteria, and the best inhibitory effect was obtained in the 100% infusion mixture treatment.
Effectiveness of Dexamethasone, Methylprednisolone and Hydrocortisone Administration on LDH, CRP, D-and PaO2/FiO2 Ratio
Authors: Zubaidi Muhammad , Isa Mohammad , Nurrasyidah Ira
Published: March 2023

Abstract: Steroids are the standard recommended therapy for COVID-19, especially in critically ill patients. Previous studies have shown that steroids are beneficial for inflammatory markers such as C-Reactive Protein (CRP), Lactate Dehydrogenase (LDH) and D-dimer as well as the value of the PaO2/FiO2 ratio. This study aims to determine the differences in the effects of the steroid’s dexamethasone, methylprednisolone and hydrocortisone on inflammatory markers. This research is a retrospective cohort study. The samples were all COVID-19 patients with critical degrees from January to June 2021. The independent variables were dexamethasone, methylprednisolone and hydrocortisone. The dependent variables are CRP, LDH, D-dimer and the ratio of PaO2/FiO2. The statistical test used was the Kolmogorov-Smirnov test and continued with the Kruskal-Wallis test and the Mann-Whitney U test. A total of 148 subjects with a total sample of dexamethasone 60, methylprednisolone 55 and hydrocortisone 33. The statistical test results showed a significant difference in the effect of the steroid dexamethasone, methylprednisolone and hydrocortisone on the value of the PaO2/FiO2 ratio (p=0.04). Administration of hydrocortisone and dexamethasone was statistically superior to methylprednisolone for increasing the PaO2/FiO2 ratio.
Total Sleep Deprivation Reduces Quality of Spermatozoa in Male Albino Rat (Rattus norvegicus)
Authors: Arjadi Fitranto , Wisesa Sindhu , Indriani Vitasari
Published: March 2023

Abstract: Sleep deprivation-induced stress decreases the quality of spermatozoa due to the increase of glucocorticoid levels through the hypothalamic-pituitary-adrenal axis. Sleep recovery (SR) restores the effect of stress due to sleep deprivation by decreasing lipid peroxides and other free radicals and increasing glutathione antioxidants. This study aims to determine the spermatozoa quality in male albino rats (Rattus norvegicus) after the stress induction by diverse sleep deprivation protocols. This study is experimental research with posttest-only control group design in 30 male albino rats divided into five groups consisting of group I for negative control (no induction of sleep deprivation), group II for paradoxical sleep deprivation (PSD), group III for total sleep deprivation (TSD), group IV for PSD followed by SR, and group V for TSD followed by SR. PSD and TSD were performed by depriving rats sleep for 20 and 24 hours/day, respectively, for five days. SR was done for the next five days after PSD or TSD. Shapiro-Wilk test was used for normality of data distribution, and Levene's test was used for variance homogeneity. Comparative hypothesis was then analyzed with One Way Analysis of Variance (ANOVA) test, and significance between groups was analyzed with Tukey's Post-Hoc test. Group III (TSD) demonstrated the lowest mean of spermatozoa count (41,53±2,29), spermatozoa morphology (13,00±2,91), spermatozoa viability (31,00±7,39), and percentage of motility rate (37±8,58%) among all groups. In conclusion, total sleep deprivation (TSD) decreases the quality of spermatozoa in male albino rats (Rattus norvegicus).
Identification Risk Factors of Stroke: Literature Review
Authors: Agianto Agianto , Yulise Bellia , Agustina Rismia , Rizany Ichsan
Published: March 2023

Abstract: State spending to deal with stroke is quite large every year due to the high incidence of stroke. Data from the Ministry of Health of Indonesia mentions an increasing number in health financing every year, the country financed stroke services by 2.56 trillion in 2018. The magnitude of the incidence of stroke can be lowered by controlling the risk factors of stroke. This study aimed to identify stroke risk factors, both those modifiable risk factors and irreversible risk factors. Research is conducted with a literature review using descriptive study methods or correlation analysis with cross sectional approaches. Sixteen articles identified from Google scholars and Garuda databases in the 2015-2020 range, and were analysed using JBI critical appraisal tools-checklist for analytical cross-sectional studies and JBI critical appraisal tools-checklist for prevalence studies.  Synthesis narrative was used to analyse the articles. Out of 16 articles examined the modifiable risk factors were hypertension, dyslipidemia, diabetes mellitus, lack of physical activity, blood sugar levels, cholesterol levels in blood, alcohol and drug consumption, kidney disease, tuberculosis, heart disease, heart failure, obesity, central obesity, atrial fibrillation and also smoking are declared associated with the incidence of stroke. The irreversible risk factors are age, gender, education, family history, income employment, previous stroke history, and rural and urban distribution. Risk factors divided into two categories modifiable risk factors and irreversible risk factors. It is important to know the risk factors of stroke in order prevent the occurrence of stroke as early as possible by avoiding modifiable stroke risk factors. Hypertension, smoking, diabetes mellitus obesity, dyslipidemia, and lack of activity are the most modifiable stroke risk factors identified in the articles. The most irreversible risk factors identified in the article are age, gender, and level of education.
Efektivitas Beauveria bassiana vuill. dengan Berbagai Media Pembiakan Massal untuk Mengendalikan Wereng Coklat (Nilaparvata lugens stal.)
Authors: Rosita Rosita , Soedijo Samharinto , Aidawati Noor
Published: March 2023

Oryza sativa L. can be called an important commodity because it is used as a staple food. Farmers in cultivating rice expect high yields, but there are obstacles that cause yields to decline, namely the attack of the Brown Stem Planthopper (BSP) (Nilaparvata lugens Stal.) which can lead to crop failure. Farmers controlling N. lugens still use insecticides. Control by using insecticides is known to have a negative impact on users and the environment and can cause resistance, resurgence and residue. One of the safe controls is the use of Beauveria bassiana as an entomopathogenic fungus. This study was conducted to determine the effectiveness of B. bassiana cultured on various media in controlling WBC attacks. The design used was a Completely Randomized Design (CRD) with 6 treatments, namely control treatment without B. bassiana, control with B. bassiana grown on PDA media, B. bassiana grown on corn media, and B. bassiana growing on media. grown on rice media, given B. bassiana grown on bran media, given B. bassiana grown on husk ash and repeated 4 times. Observations were made after one application by observing mortality (mortality) every 24 hours for 7 days. The results of the observation that the highest mortality percentage was found in the corn media treatment reaching 47.50%, rice media 40%, bran media 18.75% while the lowest was found in the husk media, namely 15%.
Evolving jurisprudence on conversion therapy: Reconsidering ethics in mental health systems
Authors: Kottai Sudarshan R , Ramprakash Rajalakshmi
Published: March 2023

Since the Delhi High Court judgement (2009), reading down IPC 377 that criminalised homosexuality, the Indian judiciary has been at the forefront of invoking constitutional morality to uphold LGBTQIA+ rights. In contrast, the mainstream mental health systems have failed to uphold human rights and protect LGBTQIA+ people ethically, except for a few position statements. Though the Supreme Court directed the mental health fraternity to exercise utmost sensitivity to LGBTQIA+ issues, they have not risen to the occasion. The absence of gender affirmative guidelines and failure to put in place punitive action against those practising conversion therapies set apart Indian mental health systems, in stark contrast to international mental health associations. Here, we review landmark judgments and the actions of professional mental health bodies regarding LGBTQIA+ rights in India, from 2009 to 2022 — especially those regarding conversion therapies and the discriminatory medical curriculum — to examine the deepening crisis of public health ethics.
Two new distribution records of Dendrobium (Orchidaceae), with an updated checklist of Dendrobium for Laos
Authors:   Faculty of Environmental Sciences, National University of Laos, Dongdok Campus, Xaythany District, Vientiane Capital, Laos, Phonepaseuth Phongphayboun , Souvannakhoummane Keooudone ,   Faculty of Natural Science, National University of Laos, Dongdok Campus, Xaythany District, Vientiane Capital, Laos, Xayyasith Santi ,   Faculty of Environmental Sciences, National University of Laos, Dongdok Campus, Xaythany District, Vientiane Capital, Laos, Keovongsy Chanthavong ,   Faculty of Environmental Sciences, National University of Laos, Dongdok Campus, Xaythany District, Vientiane Capital, LaosFaculty of Environmental Sciences, National University of Laos, Dongdok Campus, Xaythany District, Vientiane Capital, Laos, Soulida Khamnuk ,   Faculty of Environmental Sciences, National University of Laos, Dongdok Campus, Xaythany District, Vientiane Capital, Laos, Souladeth Phetlasy ,   Faculty of Forest Science, National University of Laos, Dongdok Campus, Xaythany District, Vientiane Capital, Laos
Published: March 2023

Two new records of Dendrobium, D. daklakense, and D. metrium, are reported for the flora of Laos for the first time. Photographs, information on habitat and ecology, vernacular names and additional notes for each species are given based on collections from Dak Cheung Plateau, Sekong Province (D. daklakense), and Phou Khao Khouay National Park, Vientiane Province (D. metrium). An updated checklist with classification section of Dendrobium in Laos is also provided.
Under the Shade of Kings
Authors: Nisnevich Y.
Published: March 2023

The article is devoted to the problem of the relationship between monarchy and democracy, the question of whether the monarchical form of government is able to adapt to modern realities and how compatible it is with democracy. This problem is not well understood, and no new political theory has been developed on it since Walter Bagehot published his classic work “The English Constitution” about the British system of government in 1867. The phenomenon of the “northern kingdoms” is investigated, which lies in the fact that the kingdoms of Denmark, the Netherlands, Norway and Sweden have earned advanced positions in socio-economic development and evolution of democratic institutions and are at the top of the modern states’ development ratings. A possible explanation for this phenomenon is that the leading positions of the northern monarchies in the evolvement of the political, and as a result, the socio-economic sphere are largely due to the high level of unity of the nation, in which the form of government of these states, the democratic constitutional monarchy, plays a decisive role. To confirm this research hypothesis, the work of Phillip Manow “In the Kings’ Shadow” is used. This work suggests a possible explanation of this phenomenon providing historical and political analysis of the transition of the nation’s political representation from the King to the parliament when moving from absolute monarchy to democracy. In constitutional monarchies, the monarch preserves in symbolical and representational form the concept of national cohesion and the nation’s common will removing it from the competitive field of politics, therefore, monoethnic northern kingdoms have a high level of solidarity and national unity “in the shadow of the king”. This significantly affects coherence and efficiency of the system of public authority and public institutions. Moreover, in constitutional monarchies, the Crown symbolizes and represents historical continuity, cultural and ethnic traditions and norms of behavior; representatives of monarchial dynasties can serve as more adequate role models than elected politicians.
Tax Instruments to Stimulate Innovations in EU Countries
Authors: Rastvortseva S. , Panina E. , Kocheshkov M.
Published: March 2023

Solow–Swann’s neoclassical theory of economic growth shows that without technological progress, capital accumulation can only lead to a short-term increase in the growth rate of output per capita. The challenges of sustainable innovative development in many countries are coming to the fore today. The creation, dissemination and use of innovations occur in companies, universities, scientific organizations (micro-level), between economic entities within the framework of regional (meso-level) and national (macro-level) innovation systems, as well as at the international level. Innovation support is carried out at the meso-level, focuses on companies and organizations, and is evaluated at the level of the country as a whole. State support for innovation is necessary for the following reasons: 1) the ease of information transfer puts manufacturing companies in a less favorable position compared to consumer companies; 2) the difficulty of obtaining a loan for R&D with the risk of information leakage and lack of confidence in the final results; 3) the socio-economic system of the country receives more benefits from innovation than all companies in the aggregate. The article discusses such types of support as government subsidies and grants, tax incentives, measures for the development of human capital in an innovative environment, competition and intellectual property protection policy. In the international practice of stimulating innovation, tax incentives are used, 1) allowing to reduce R&D costs, 2) based on non-reduction of R&D expenditures and 3) preferential tax regimes derived from innovation activities. It is shown that the methodological approaches used to assess the effectiveness of tax measures are the B-index (calculated and published by the OECD by country), the analysis of the validity of tax instruments and the use of the European Tax Analyzer model – computer modeling. The analysis of innovative development showed that the European Union in terms of the number of patents, residents and non-residents, the share of researchers in the total population and the share of R&D expenditures in GDP for 2000–2022 is often inferior to China, the USA, Japan and Korea, but generally has a positive development trend. The most popular tools in the European Union countries are tax deductions, “super deductions”, R&D grants and other incentives. There is no direct correlation between the number of benefits and the level of innovation development. At the same time, it is noticeable that countries using a large number of support tools are becoming attractive to innovative companies and entrepreneurs. The article analyzes the measures of state support for R&D during the COVID‑19 pandemic. Of these, the most relevant are grants and subsidies, and tax benefits. The analysis of tax instruments for stimulating innovation carried out in the article may be useful in the implementation of appropriate policies in other countries.