bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECT OF URBAN INNOVATION ON LAND FINANCE DEPENDENCE: EVIDENCE FROM 233 CHINESE CITIES
Authors: Fu Wenyan , Zhao Xiaofeng , Lin Sheng-Hau , Li Yi , Wang Zhonghan
Published: September 2023

Unlike most studies on urban innovation, which focus on the effects of land-use policies, this study investigates the effect of urban innovation (UI) on land finance dependence (LFD). In China, innovation-related policies are intended to create a shared business environment where new entrepreneurs can contribute to achieving sustainable economic growth. This study analyzes the spatiotemporal dynamics of LFD and UI from 2005 to 2019 using the spatial autocorrelation model and dynamic spatial Durbin model. It finds a positive spatial association between LFD and UI throughout the studied regions during the study period. It also reveals a significant inhibitory effect of UI on LFD and a negative impact on the LFD of neighbouring cities. Moreover, the inhibitory effects will increase over time. Lastly, this study shows varied impacts of UI on LFD in different regions, especially in eastern China. Important policy recommendations for high-quality development in China are provided.
Revisiting Galactic Disk and Spiral Arms Using Open Clusters
Authors: Joshi Yogesh C. , Malhotra Sagar
Published: September 2023

We use the largest catalog of open clusters in the post-Gaia era to provide an observational view of the Galactic disk. By compiling physical parameters such as age, distance, and kinematic information, we investigate the spatial distribution of open clusters and revisit the spiral arms and other asymmetries in the Galactic disk. Using young open clusters as a tracer of spiral arms, we map the spiral structure of the Galaxy and find that most of the clusters start migrating away from the spiral arms in about 10–20 Myr and fill the interarm regions as they age. Using the 3D kinematic information on 371 open star clusters, we derive different individual pattern speeds for spiral arms that closely follow the rotation curve of the Milky Way, hence favoring the transient nature of spiral arms in the Milky Way. The pattern rotation speeds of each spiral arm suggest that the spiral arms have not accelerated in the last 80 Myr. Based on the distribution of open clusters younger than 700 Myr above or below the Galactic plane, we found a solar offset of z
⊙ = 17.0 ± 0.9 pc north of the Galactic plane and estimated the scale height z

h
= 91.7 ± 1.9 pc from the Galactic plane.
GRB-SN Association within the Binary-driven Hypernova Model
Authors: Aimuratov Y. , Becerra L. M. , Bianco C. L. , Cherubini C. , Valle M. Della , Filippi S. , Li 李 Liang 亮 , Moradi R. , Rastegarnia F. , Rueda J. A. , Ruffini R. , Sahakyan N. , Wang 王 Y. 瑜 , Zhang 张 S. R. 书瑞
Published: September 2023

Observations of supernovae (SNe) Ic occurring after the prompt emission of long gamma-ray bursts (GRBs) are addressed within the binary-driven hypernova (BdHN) model where GRBs originate from a binary composed of a ∼10M
⊙ carbon–oxygen (CO) star and a neutron star (NS). The CO core collapse gives the trigger, leading to a hypernova with a fast-spinning newborn NS (νNS) at its center. The evolution depends strongly on the binary period, P
bin. For P
bin ∼ 5 min, BdHNe I occur with energies 1052–1054 erg. The accretion of SN ejecta onto the NS leads to its collapse, forming a black hole (BH) originating the MeV/GeV radiation. For P
bin ∼ 10 min, BdHNe II occur with energies 1050–1052 erg and for P
bin ∼ hours, BdHNe III occur with energies below 1050 erg. In BdHNe II and III, no BH is formed. The 1–1000 ms νNS originates, in all BdHNe, the X-ray-optical-radio afterglows by synchrotron emission. The hypernova follows an independent evolution, becoming an SN Ic, powered by nickel decay, observable after the GRB prompt emission. We report 24 SNe Ic associated with BdHNe. Their optical peak luminosity and time of occurrence are similar and independent of the associated GRBs. From previously identified 380 BdHN I comprising redshifts up to z = 8.2, we analyze four examples with their associated hypernovae. By multiwavelength extragalactic observations, we identify seven new episodes, theoretically explained, fortunately not yet detected in Galactic sources, opening new research areas. Refinement of population synthesis simulations is needed to map the progenitors of such short-lived binary systems inside our galaxy.
Prevalence of Dentin Hypersensitivity in a Target Subjects in Hanoi, Vietnam
Authors: Hong Dinh Dieu , Hai Trinh Dinh , Phuong Vu Le , Anh Tran Thi Ngoc , Anh Truong Thi Mai , Huong Do Thi Thu , Anh Trinh Hai
Published: September 2023

BACKGROUND: Dentin hypersensitivity (DH) is a short pain when dentin is exposed to external stimuli such as: Thermal, vapor, rubbing, osmotic, or chemical stimuli without pathological or any other dental defect and in normal teeth, that level of stimulation is not sufficient to cause pain. Besides tooth decay and periodontal disease, DH is the top concern of Odonto-Stomatology doctors.
AIM: The aim of this study was to study the prevalence of DH in Hanoi, Vietnam, in two groups (workers at Hanvico Company and dental students at the University of Medicine and Pharmacy, VNU, Hanoi, Vietnam).
MATERIALS AND METHODS: The study was conducted on 500 subjects which consisted of 288 workers at Hanvico Company and 212 Odonto-Stomatology students at the University of Medicine and Pharmacy, VNU. The study subjects were examined intraorally and diagnosed with DH to vapor and tactile stimuli using the Yeaple Probe electronic probe.
RESULTS: It was found that the prevalence of DH is 20.4% in Hanoi, Vietnam, with no difference between men and women. The highest prevalence of DH is in group 40–49 years of age group.
CONCLUSION: It was found that there is a moderate prevalence of DH in Hanoi, Vietnam. The cervical wear, tooth wear, gingival shrinkage, and a diet high in acid showed a high prevalence of DH.
Proliferative Activity of Myoepithelial Cells in Normal and Diabetic Parotid Glands Based on Double Immunostaining Labeling
Authors: Hassan Sherif , Bamaga Ibraheem
Published: September 2023

AIM: This study aimed to examine the effect of diabetes mellitus on the histology of parotid glands and to give a scientific overview of the distribution and the proliferative activity of myoepithelial cells (MECs) encircling both ducts and acini in parotid gland of both normal and diabetic mongrel dogs.
MATERIALS AND METHODS: Twelve male mongrel dogs were used in the experiment and divided into two equal groups, group I, control group, group II, dogs with alloxan-induced diabetes. The dogs of the group II were injected by fresh preparation of a single dose of 100 mg/kg body weight of alloxan monohydrate dissolved in physiological saline. Ten days later, blood glucose level was determined using enzymatic colorimetric test;  dogs presented a glucose level at or above 200 mg/dL were included in the diabetic group of the experiment. Three months later, dogs were sacrificed and the parotid glands from all groups were dissected and prepared for histological examination and double immunohistochemical expression of both actin and proliferating cell nuclear antigen (PCNA).
RESULTS: Histological findings using H and E staining confirmed that the parotid gland parenchyma of the diabetic group had glandular atrophy characterized by loss of normal gland structure, acinar degeneration, and dilatation of the duct system with the presence of duct like structure. Moreover, there was a predominance of the fibrous component with the presence of fat cells within the gland compartments. Immunohistochemical findings of parotid gland of control group revealed positive scattered actin staining of weak to mild quantity in cells embracing some acini and intralobular ducts. Expression of PCNA in actin-positive cells revealed few scattered reactions embracing some acini  and  small ducts. Parotid gland of diabetic dogs revealed positive actin staining of mild-to-moderate quantity in the cells encircling the acini, intralobular, and some interlobular ducts. Expression of PCNA in actin- positive cells revealed mild-to-moderate positive reaction more concentrated in the cells surrounding both acini and intercalated ducts.
CONCLUSION: Routine histological findings of  diabetic dogs in  our  findings showed abundant pathological changes in parenchymal tissue elements, including acinar, ductal, and MECs that had a significant impact on saliva production and secretion resulting in dry mouth. The proliferative activity of MECs in the control group indicated a routine regeneration process, whereas the abundant proliferative activity in the  diabetic group might indicate pathological transformation rather than regeneration, especially because no remedial measures were taken during this investigation.
Editorial
Authors: Martin Jane , Yarker Patrick
Published: September 2023

England's state education system is increasingly controlled from the centre while being highly fragmented. Elements within the system, and forces acting on it, lean towards privatisation. Public, preparatory and private schools endure. Grammar schools persist, vitiating fair educational
opportunities in many localities and preventing the sustained development in practice of a better conception of education for all. At every age and stage, high-stakes summative assessment enforces a narrowed curriculum, straitjackets pedagogical approaches and drains the joy from teaching
and learning. Labelling young people by so-called 'ability', and segregating cohorts into 'ability' sets, conspire to limit what is possible for individuals and groups. Assumptions about 'ability' or a specious 'ability-range' are yet to be eradicated. Nor have we yet shaped pedagogy commensurate
with the conception of children as the people best trusted to know how they learn, as intrinsically driven to learn, and able when conditions are conducive always to go on learning. Nevertheless, the comprehensive ideal is alive, thanks to the dedication of practitioners and educationalists,
the commitment of parents and carers, and the work of trade unions and activist groups campaigning for it on the ground. As a journal, FORUM will continue to be a platform from which to argue for comprehensive education. Selection, division, elitism and all that goes to make up a competitive
mindset in education will be challenged in our pages. FORUM will spread news of the success of comprehensive education in this country and beyond. It will explore the implications and meet the many challenges of the comprehensive ideal, and so take it forward.
Ceci n’est pas une « Organisation » : quelle épistémologie pour le bazaar ?
Authors: Astier Benjamin , Labour Michel , Leleu-Merviel Sylvie
Published: September 2023

L’article remet en cause l’application épistémologique des principes de la logique aristotélicienne classique aux « Organisations ». Ces dernières évoluent désormais dans une société de la connaissance, empreinte de numérique et de stratégies d’ open innovation . Pour cela, l’étude de cas se fonde sur des observations et des entretiens semi-ouverts auprès de participants de Fashion Green Hub (FGH) ainsi que sur le support numérique Slack . FGH présente un organisé-organisant, émergeant tel un bazaar (Raymond, 1999), regroupant des protagonistes autour de valeurs et d’idées clés attractives. Ces nouvelles noorganisations impliquent des changements managériaux, en rapport avec les idées, l’incertitude, l’engagement et la confiance vécue.
Quelle place pour l’idéologie dans la Russie de Vladimir Poutine ?
Authors: Chappedelaine Bernard
Published: September 2023

Après 70 ans de communisme, les Russes aspirent à vivre dans un « pays normal » et, fin 1999, Vladimir Poutine marque son refus du « rétablissement de toute idéologie étatique ». Depuis, la place de l’idéologie dans la Russie poutinienne est controversée. L’invasion de l’Ukraine, présentée comme un conflit de civilisation, met à l’épreuve la cohésion de la société et de l’État russes. La question du retour à une idéologie officielle est posée.
L’Europe face aux migrations
Authors: O’Rourke John
Published: September 2023

Les migrations vers l’Europe sont moins nombreuses qu’un débat public mal géré peut le laisser croire. Elles posent néanmoins des problèmes qui doivent être gérés à la fois en agissant sur les déséquilibres politiques locaux et sur les formes juridiques de l’accueil en Europe : conditions de l’asile, organisation des éloignements, démantèlement des réseaux de passeurs… Toutes politiques à mettre sur pied collectivement et dans le respect des intérêts et valeurs de l’Union européenne.
Overcoming Barriers of Incorporating Diversity, Equity, and Inclusion Initiatives in Nursing Schools
Authors: Kearney Kelly , Wilson Charmaine D. , Ramirez Elda
Published: September 2023

Background:

To create an inclusive environment in nursing education, challenges to incorporating change must be addressed including institutional racism, power differences, privilege, and implicit biases (O'Connor et al.). This article discusses barriers that interfere with the implementation of diversity, equity, and inclusion (DEI) initiatives within schools of nursing and offers strategies for building a culture of inclusivity at academic institutions.

Method:

This article is based on factual, researched, and firsthand information.

Results:

Administrators and stakeholders need to determine how DEI is incorporated into their institution's mission, vision, and values. Forming a DEI council that consists of equal representation from faculty, staff, and students will foster inclusiveness to incorporate DEI initiatives within schools of nursing and will allow outcomes to be measured.

Conclusion:

Barriers should be identified and removed to make schools of nursing a safe and inclusive zone for faculty, staff, and students.

[
J Nurs Educ
. 2024;63(1):53–56.]
Development of Gerontological Learning Objectives to Enhance Nursing Educational Curricula
Authors: Davey Meaghan , Taucar Linda Sheiban , Heyer Michelle , Boscart Veronique
Published: September 2023

Background:

Many nursing schools are challenged to provide adequate gerontological education to students despite the enormous benefits to students' careers and society. This project developed student learning objectives to be used by nursing faculty to facilitate enriched gerontology courses and program curricula.

Method:

The project team drafted a comprehensive list of nursing student learning objectives based on the 2020 Canadian Gerontological Nursing Association Standards of Practice and Competencies and included relevant supportive references. Subsequently, 20 gerontological nurse experts reviewed the learning objectives through a modified Delphi process via online Qualtrics surveys (two rounds).

Results:

A total of 176 learning objectives were rated in round one for importance, measurability, feasibility, and interpretability; these were amalgamated to 47 learning objectives for review in round two.

Conclusion:

Thirty-three learning objectives were identified and validated that can be used by nursing schools to offer increased opportunities for gerontological learning.

[
J Nurs Educ
. 2024;63(4):256–260.]
Research on impact reduction of flexible boundary particle damping honeycomb plate based on discrete element multi body dynamics coupling
Authors: Hu Dike , Wang Hua , Huang Zijie , Xiao Wangqiang
Published: September 2023

The exposed platform is the main component of precision instruments such as pyrotechnic separation devices and load adapters, and its dynamic response characteristics are a key factor affecting the stability of aircraft. When the pyrotechnic separation device explodes, the exposed platform will be subjected to high-frequency, transient and high-order pyrotechnic impacts. High order pyrotechnic impacts can easily cause damage to sensitive components in onboard equipment, resulting in incalculable losses. Filling the honeycomb core cavity inside the exposed platform with a flexible boundary particle damper can effectively attenuate the pyrotechnic impact load after experiencing a large number of discontinuous structures. A numerical model of a flexible boundary particle damper and an exposed platform honeycomb panel was established through the coupling of discrete element and multi body dynamics. The effects of particle material, particle size, filling rate and flexible boundary film thickness on the impact reduction performance of the flexible boundary particle damper were analyzed, and the optimal characteristic parameters of the flexible boundary particle damper were obtained. The impact test was conducted on the honeycomb panel of the exposed platform using a light gas gun impact experiment, verifying the impact reduction effect of the flexible boundary particle damper and the accuracy of the numerical model. Finally, a pyrotechnic impact experiment was conducted on the exposed platform honeycomb panel with the optimal parameter flexible boundary particle damper. The experimental results showed that the impact reduction effect of the flexible boundary particle damper with this parameter reached 55.52%.
Multi-omics analysis and validation of the tumor microenvironment of hepatocellular carcinoma under RNA modification patterns
Authors: Yao Yuanqian , Lv Jianlin , Wang Guangyao , Hong Xiaohua
Published: September 2023

Background: Multiple types of RNA modifications are associated with the prognosis of hepatocellular carcinoma (HCC) patients. However, the overall mediating effect of RNA modifications on the tumor microenvironment (TME) and the prognosis of patients with HCC is unclear. Methods: Thoroughly analyze the TME, biological processes, immune infiltration and patient prognosis based on RNA modification patterns and gene patterns. Construct a prognostic model (RNA modification score, RNAM-S) to predict the overall survival (OS) in HCC patients. Analyze the immune status, cancer stem cell (CSC), mutations and drug sensitivity of HCC patients in both the high and low RNAM-S groups. Verify the expression levels of the four characteristic genes of the prognostic RNAM-S using in vitro cell experiments. Results: Two modification patterns and two gene patterns were identified in this study. Both the high-expression modification pattern and the gene pattern exhibited worse OS. A prognostic RNAM-S model was constructed based on four featured genes (KIF20A, NR1I2, NR2F1 and PLOD2). Cellular experiments suggested significant dysregulation of the expression levels of these four genes. In addition, validation of the RNAM-S model using each data set showed good predictive performance of the model. The two groups of HCC patients (high and low RNAM-S groups) exhibited significant differences in immune status, CSC, mutation and drug sensitivity. Conclusion: The findings of the study demonstrate the clinical value of RNA modifications, which provide new insights into the individualized treatment for patients with HCC.
Optimization of pre-treatment and culture conditions for bioethanol yield enhancement from Azolla filiculoides substrate using Saccharomyces cerevisiae
Authors: Christy E. J. S. B. A. , Kapilan R. , Wickramasinghe I. , Wijesekara I.
Published: September 2023

Increasing human population and extreme consumption of fossil fuels create the potential to generate alternative energy sources. Bioethanol is an alternative and renewable energy resource for fossil fuels, which can be generated from low-cost raw materials. The objective of the study is to optimize pretreatment and culture conditions to enhance bioethanol production from Azolla filiculoides substrate using Saccharomyces cerevisiae. The A. filiculoides was collected from fresh-water ponds, cleaned, dried, milled to fine powder and then autoclaved for 15 min at 121 ℃. When A. filiculoides substrate was pre-treated with different acids and alkaline separately and alcohol production was monitored, significantly higher alcohol (0.1%) was produced with 1 M H2SO4, thus it was selected as the best pre-treatment agent.
Underutilized crops as a resource to combat the food, nutrient, and economic security in Sri Lanka
Authors: Nakandalage Niluka , Anuruddi H. I. G. K.
Published: September 2023

Food insecurity in Sri Lanka has risen dramatically owing to various factors, including the COVID-19 pandemic and the recent economic crisis. Movement and activity restrictions imposed to control the spread of the pandemic, combined with acute shortages of essential food items, have had a severe impact on people's livelihoods, resulting in food insecurity and increased vulnerability to malnutrition. Provision of quality food for the community at a minimum cost is prioritized by the government due to consecutive seasons of poor harvests, foreign exchange shortages, higher food inflation, and reduced household purchasing power. Currently, the focus has shifted to find sustainable food sources to meet both the nutritional and economic needs of communities. Meanwhile, consumption patterns based on a few dominant species of major food crops are recognized as one of the biggest threats to global nutrition and food security and this is also true for Sri Lanka. As a result, there is a growing need to discover new food crops targeting healthy and diversified dietary patterns.Effective use of underutilized crops (UCs) in this context appears to be one of the imperative means to minimize the pressure mounted on major crops as they could produce different kinds of foods rich with macro- (Protein and carbohydrates) and micronutrients (Vitamins and minerals- Potassium, Calcium, Magnesium, Zinc, Iron). Fruits, vegetables, cereals tubers/yams and medicinal plants are examples for different groups of underutilized crops that are nutrient-dense, health-promoting, and climate-resilient. UCs are well adapted to a wide range of soil and climatic conditions as well as low-input farming systems. Their systematic cultivation is advantageous in rural areas where people have poor income generation and lack of market accessibility. Therefore, this rich genetic diversity could be used to enhance food and economic security in numerous ways, most importantly through, direct access to a diversity of nutritionally-rich foods, increased purchasing power from savings on food bills and year-round income from selling the value-added products. It is essential that people know how best to make use of these invaluable natural resources to ensure their wellbeing. This review discusses on the positive aspects of promoting UCs on addressing food, nutrient and economic security in Sri Lanka.
Facial Sentiment Recognition using artificial intelligence techniques.
Authors: Xuan Chi Vuong , Cong Vinh Phan
Published: September 2023

Facial emotion recognition technology is used to analyze and recognize human emotions based on facial expressions. This technology uses deep learning models to classify facial expressions, eyes, eyebrows, mouth, and other facial expressions to determine a person's emotions. The application of facial emotion recognition in the field of education is a potential way to evaluate the level of student absorption after each class period. Using cameras and emotion recognition technology, the system can record and analyze students' facial expressions during class. In this paper, we use the Convolutional Neural Network (CNN) algorithm combined with the linear regression analysis method to build a model to predict students' facial emotions over a period of time camera recorded.
Exploring Integration Mechanism of Music Instructional Design and Education Informatization
Authors: Wang Chenchen
Published: September 2023

INTRODUCTION: In the new era of information society, the knowledge reform of school music education is getting more and more attention. Traditional teaching methods need to make full use of information technology. They cannot meet the current learning needs because the learning of information technology teaching is an essential means to realize modern learning. , therefore, the application of information technology in music education meets the requirements of the times.
OBJECTIVES: To improve traditional teaching methods by utilizing modern teaching techniques so that students can gain more knowledge. With the help of modern technology and information technology, secondary music education can change the students' audiovisual experience, enrich their musical experience, and deepen their understanding and memorization of knowledge.
METHODS: In this paper, use a neural network algorithm to explore the integration mechanism of music teaching design and education information technology, optimize the traditional information technology teaching platform, improve the stability of the music teaching platform, and further improve the level of network teaching from the feedback of students and teachers.
RESULTS: This study's results found that this experiment's educational platform could motivate students to manage teaching and actively participate in music teaching and lessons. However, due to the real-time nature of information technology, it removes doubts between the parties and facilitates communication between teachers and students. The primary goal of music education is to perceive the attraction of music in terms of sight and sound, to relax the mind and body, and to develop a musical personality. From this perspective, it is also necessary to utilize modern information technology to change teachers' traditional teaching methods in classical performance and singing.
CONCLUSION: With the help of modern technology and information technology, secondary music education can change the audiovisual experience of students, enrich their musical experience, and deepen their understanding and memorization of knowledge. The information system can motivate students to manage teaching and actively participate in music teaching.
On relative bounds for interacting Fermion operators
Authors: Bach Volker , Rauch Robert
Published: September 2023

We consider a system of interacting fermions whose Hamiltonian is unitarily transformed
so that the interaction is a quartic perturbation of the Hartree–Fock effective Hamiltonian. It is shown
under natural model assumptions that the interaction does not admit a relative bound with respect to
the effective Hamiltonian that is uniform in the system’s size.

This bound is exemplified on the Hubbard model with nearest neighbor interaction on a discrete

d

-dimensional torus of length

L

around its Hartree–Fock ground state and derive relative bounds of the effective interaction with respect to the effective kinetic energy. It is shown that there are no
relative bounds uniform in

L

.
Generalized positive energy representations of groups of jets
Authors: Niestijl Milan
Published: September 2023

Let

V

be a finite-dimensional real vector space and

K

a compact simple Lie group with Lie algebra

\mathfrak{k}

. Consider
the Fréchet–Lie group

G := J_0^\infty(V; K)

of

\infty

-jets at

0\in V

of smooth maps

V \to K

, with Lie algebra

\mathfrak{g}=J_0^\infty(V; \mathfrak{k})

. Let

P

be a Lie group and write

\mathfrak{p}:=\operatorname{Lie}(P)

. Let

\alpha

be a smooth

P

-action on

G

.
We study smooth projective unitary representations

\bar{\rho}

of

G\rtimes_\alpha P

that satisfy a so-called generalized
positive energy condition. In particular, this class captures representations that are in a suitable sense compatible with a
KMS state on the von Neumann algebra generated by

\bar{\rho}(G)

. We show that this condition imposes severe restrictions
on the derived representation

d\bar{\rho}

of

\mathfrak{g}\rtimes \mathfrak{p}

, leading in particular to sufficient conditions for

{\bar{\rho}}|_{G}

to factor through

J_0^2(V; K)

, or even through

K

.
Об одном функционале от числа появившихся неперекрывающихся цепочек исходов полиномиальной схемы и его связи с энтропией
Authors: Savelov M P
Published: September 2023

Рассмотрим $n$ независимых цепочек, состоящих из $k$ независимых полиномиальных
испытаний с $M$ исходами. Предполагается, что $n, k \to \infty$ и
$\ln(n/M^k)=o(k)$. Установлена асимптотика нормированного логарифма числа
появившихся цепочек и указана связь данного функционала с энтропией.
Библиография: 11 названий.
Аппроксимация функций Матье функциями параболического цилиндра
Authors: Zlobina Ekaterina Andreevna
Published: September 2023

Рассматривается классическое уравнение Матье с комплексными коэффициентами специального вида.
Строятся простые неравномерные асимптотики его решений в терминах функций параболического цилиндра.
Библиография: 11 названий.
Aluminum Alloy, Sheet and Plate 4.4Mg - 0.70Mn - 0.15Cr (5083-O) Annealed
Authors:   AMS D Nonferrous Alloys Committee
Published: September 2023

This specification covers an aluminum alloy in the form of sheet and plate 0.051 to 8.000 inches (1.30 to 203.20 mm), inclusive, in thickness (see 8.5).
Prawne i ekonomiczne aspekty długu publicznego w krajach Unii Europejskiej w kontekście bezpieczeństwa finansów publicznych
Authors: Ważna Elżbieta
Published: September 2023

The SARS-CoV-2 coronavirus pandemic has posed unprecedented challenges to the world economy, forcing individual countries to seek completely new solutions and non-standard measures to preserve the security of public finances, but also the continuity of economies and minimize the losses incurred. The main purpose of the article is to analyze the legal and economic determinants of public debt and budget deficit in European Union countries. It also focuses on examining the causes of public debt and assessing its level and effects on the economy.
Сytokine expression and production in severe cases of SARS-CoV-2 infection
Authors: Abramova Natalya D. , Meremyanina E. A. , Kalyuzhnaya N. O. , Poddubikov A. V. , Kostinov M. P. , Grechenko V. V. , Svitich O. A.
Published: September 2023

Most respiratory viral infections proceed in mild form including COVID-19. Gowever, some patients experience severe systemic inflammation, tissue damage, acute respiratory distress syndrome, and cytokine storm with potentially lethal outcomes. The cytokines have been thought to play an important role in immunopathology of viral infection. However, an excessive immune response, manifesting as massive release of pro-inflammatory cytokines, may cause immune damage in the body. Production and release of the cytokines in healthy individuals presumes a significant balance of inflammatory and homeostatic factors. Meanwhile, in the case of COVID-19 disease, uncontrolled increased production of cytokines often occurs with fatal consequences for patients. The aim of this work was to study the level of IL-1β, IL-18 and TNFα gene expression, as well as production of these cytokines at the level of mucous membranes of the upper respiratory tract, in particular in oral cavity, in patients with severe COVID-19 disease.

The present study included patients who recovered from severe COVID-19. The control group consisted of conditionally healthy individuals. Expression levels of the IL-1β, IL-18, and TNFα genes were determined by RT-PCR. The levels of IL-1β, IL-18 and TNFα protein production were determined by multiplex enzyme immunoassay.

The expression levels of IL-1β, IL-18 were reduced at the onset of the disease, as well as in the midpoint of the COVID-19 disease, but increased on the 30th day. The protein production of these cytokines was also reduced in the first days from the onset of the disease. The levels of pro-inflammatory TNFα cytokine was high at the onset of the disease. The level of TNFα production at the onset of the disease was also higher relative to the control group. Subsequently, the TNFα gene expression levels decreased upon progression of the disease.

Thus, the increased expression level of pro-inflammatory cytokines may be explained by the fact that the S protein of the SARS-CoV-2 virus induces increased expression of these cytokines in human monocytes. Meanwhile, appropriate protein levels remain low, especially on day 1 from the onset of the disease. Thus, one may conclude that the virus triggers pyropotosis, however, within 15-30 days from the onset of the disease, when viral replication is already minimal.
Analysis of regulatory T lymphocytes in patients with traumatic brain injury
Authors: Norka Anna O. , Vorobyev S. V. , Kuznetsova R. N. , Serebriakova M. K. , Kudryavtsev I. V. , Kovalenko S. N. , Monashenko D. N.
Published: September 2023

In recent years, traumatic brain injury (TBI) has been one of the most urgent medical and social problems due to its prevalence, predominantly affecting young people of working age, causing high mortality, disability and economic costs for treatment and subsequent rehabilitation of patients. At present, the role of patients’ immune system in evolving neuroinflammation after traumatic brain injury has been proven. Treg cell populations represent an important factor determining the outcome of the disease due to promoting induction of immunological tolerance, being a significant component of immunoregulation. As a result of our study, we found a decrease in the relative content of Treg within the total lymphocyte pool of peripheral blood, which has the CD3+CD4+CD25bright phenotype in patients of the 3rd and 4th groups, in comparison with the data from control group. Moreover, a decreased relative content of Tregs (CD4+CD25+T cells) was revealed which is due to the degree of brain tissue damage and, as a result, their migration to suppress inflammation due to production of anti-inflammatory cytokines (TGF-â, IL-10). The Treg population is heterogeneous, thus prompting us for analysis of the Treg subpopulations profile based on the expression of CD45R0 and CD62L. When assessing subpopulations of regulatory T lymphocytes within CD45Ro and CD62L, significant changes were found only in patients with brain contusion. The changes were revealed within the pool of “naive” T regulatory lymphocytes with the CD3+CD4+CD25brightCD39+ Treg phenotype, capable of producing a wide range of cytokines specific for Th1, Th2, Th17, in patients with mild, moderate and severe TBI. Meanwhile, the level of highly active CD3+CD4+CD25brightCD73+ Tregs was significantly reduced in patients with moderate and severe TBI. These changes indicate an imbalance in immunoregulatory processes resulting from extensive damage to brain tissues.
Time-dependent changes of platelet and D-dimer parameters in vaccinated versus non-immunized COVID-19 patients
Authors: Kostinov M. P. , Zhang Chen , Khrapunova I. A. , Pechenik A. S. , Utkin V. A. , Loktionova M. N. , Mashilov K. V. , Soloveva Irina L.
Published: September 2023

There are increasing data concerning changes in hematological (clinical) and biochemical blood tests in patients with COVID-19 infection, which indicate the severity of the manifestations of the infectious process. Coagulopathy often correlates with the severity of COVID-19 disease and the risk of death. In this regard, prediction of developing coagulopathy and its prevention remain quite relevant. The aim of our study was to identify differences in the content of platelets and D-dimer in patients with COVID-19. The study included cohorts of patients vaccinated against SARS-CoV-2, and those not immunized against this infection.

A prospective, randomized, observational study of the patients’ response was performed in cohorts of 588/52.2% vaccinated (vaccinated) and 588/52.2% non-immunized (non-vaccinated) patients with diagnosed COVID-19 over the period from 23.06.2021 to 01.05.2022. The levels of blood platelets and D-dimer, as well as clinical outcomes of the disease in patients with COVID-19, were studied in dynamics on days 1-2, 5-6 and 10-12 of hospitalization.

Upon admission, the normal value of the blood platelet counts did not differ between the compared groups, being 206.58 × 109 in vaccinated group and 204.85 × 109 in the unvaccinated group, respectively. a moderate increase in the concentration of D-dimer was noted in both groups upon admission, i.e., 2838.60 ng/mL in the group of vaccinated patients and 3242.08 ng/mL among the unvaccinated patients. In the course of the study, we have shown that the dynamics of D-dimer index in vaccinated versus non-immunized persons was similar according to the days of disease, showing an increase from the first day and a trend towards an higher values, starting from 5-6 days. At the same time, the dynamics in the vaccinated patients was somewhat less favorable than that of the non-immunized subjects. In the patients who were not immunized throughout the entire observation period, the platelet count exceeds the levels found in vaccinated subjects, thus suggesting higher risk of thrombosis and cytokine storm.

The data obtained show that the dynamics of D-dimer and platelet counts in vaccinated and non-immunized people is similar on appropriate terms of the illness. However, the changes are more pronounced in vaccinated cohort, but it does not indicate a greater risk of adverse outcomes.
EDUCAÇÃO E PANDEMIA
Authors: Da silva Wellem Ribeiro , De Morais Aurora Maria , Brazão-Silva Marco Túllio , Nogueira de Castro e Almeida Shirley Patrícia , Ribeiro dos Santos Gilmar
Published: September 2023

O presente estudo teve como objetivo central compreender a perspectiva de professores de ensino superior privado com o ensino remoto nos anos de 2020 e 2021, durante o distanciamento social provocado pela pandemia de COVID-19. Submetidos à uma situação de urgência, sem tempo, recursos ou oportunidade de se prepararem, como os professores se adaptaram e como enfrentaram as dificuldades? A metodologia adotada foi a pesquisa de campo, envolvendo um questionário digital com questões objetivas e outras abertas, elaborado no Google Forms, direcionado aos docentes do curso de direito de uma faculdade privada na região do norte de Minas Gerais.  Os resultados foram analisados quanto ao seu conteúdo e estatisticamente conforme a natureza da pergunta. O resultado revelou que, embora tenham se adaptado, os docentes enfrentaram inúmeros percalços, angústias e inseguranças, um cotidiano de busca de recursos didáticos alternativos e criatividade para o seguimento das aulas.  Compras de equipamentos, mudanças de layouts residenciais, conflitos, divergências familiares e ajudas mútuas fizeram parte dessa experiência docente. A conclusão que se pôde chegar é que mesmo com o estresse intrínseco ao processo de adaptação, com a todas as dificuldades enfrentadas e com todas as preocupações sobre a aprendizagem dos acadêmicos, os docentes perceberam a experiência como um evento que ampliou seus conhecimentos no segmento da comunicação informatizada e acreditam que a experiência irá impactar, de maneiras diversas, o futuro da educação superior.
ANTICAPACITISMO, PROJETO ÉTICO-POLÍTICO PROFISSIONAL DO/A ASSISTENTE SOCIAL E OS DESAFIOS DA PRÁXIS NO CENTRO ESPECIALIZADO EM REABILITAÇÃO PARA PESSOAS COM DEFICIÊNCIA
Authors: Oliveira da Silva Bismarck , Beatriz Valentim de Souza Anna , Gomes de Matos Souza Juciara
Published: September 2023

O trabalho evidencia o princípio do anticapacitismo como elemento basilar na relação entre o Projeto Ético-Político Profissional do Serviço Social (PEPPSS) com os desdobramentos da práxis do/a assistente social desenvolvido no âmbito da reabilitação de pessoas com deficiência. Enquanto relato de experiência de trabalho no Centro Especializado em Reabilitação - CER, localizado em Macaíba/RN, habilitado pelo Ministério da Saúde como serviço de reabilitação na modalidade física, intelectual, auditiva e visual, do Sistema Único de Saúde (SUS). O relato de experiência se embasou em revisão de literatura. Realizou-se o diálogo entre os fundamentos da profissão em seus princípios ético-políticos de base crítico-dialética, as mediações necessárias frente aos desafios travados no trabalho junto ao segmento PcD e a relevância da visão anticapacitista para o agir profissional praxiológico ético, crítico e de caráter transformativo.
Diálogo interreligioso e intercultural con comunidades indígenas: perspectivas y enfoques metodológicos
Authors:   Pontificia Universidad Católica de Chile, Cortés Rodríguez Rocío
Published: September 2023

En este estudio, se examinan algunos principios del diálogo interreligioso e intercultural en el contexto posterior al Concilio Vaticano II en América Latina y su influencia a través del Decreto Nostra Aetate. Se explora también la Teología India y su relevancia para promover el diálogo entre el cristianismo y las tradiciones indígenas en la región. Además, se introduce el método del Razonamiento de la Escritura, utilizado en Chile para facilitar el diálogo interreligioso e intercultural entre las tradiciones originarias, el cristianismo, el islam y el judaísmo, con el objetivo de promover un diálogo enriquecedor y respetuoso. Este estudio busca ofrecer nuevas perspectivas y enfoques metodológicos para fomentar el diálogo interreligioso e intercultural más efectivo y significativo.
Efektivitas Damar Putih dalam Pelestarian Tanaman Endemik Plasma Nutfah Oleh PT Pertamina Patra Niaga DPPU SMB II di Kota Palembang
Authors: Apriyadi Ahmad , Nirmala Lutfie Syarief Ayu , Aprilia Rada , Dwi Maharani Shinta
Published: September 2023

This research aims to describe the effectiveness of damar putih (white resin) in conserving endemic germplasm plants by PT Pertamina Patra Niaga DPPU Sultan Mahmud Badaruddin II Palembang. The study was conducted through a survey method at the Punti Kayu Palembang Tourist Park located at JL. Kol. H. Burlian, Srijaya, Alang-alang Lebar District, Palembang City, South Sumatra, 30151. Based on the Minister of Forestry Decree dated March 7, 1985 No. 57/Kpts-II/1985, the Punti Kayu Forest area was designated as a tourist forest that serves as the lungs of the city. On October 7, 2002, the Minister of Forestry through Decree No. 9273/Kpts-II/2002 designated Punti Kayu as a conservation forest with a function as a Natural Tourist Park covering an area of ​​39.9 hectares. This research was conducted in July 2023. Based on the study, there was an increase in the number of protected flora, particularly supported by PT Pertamina Patra Niaga DPPU SMB II, with a total of 1,668 trees. In 2023, the data for planting trees of the rare endemic biodiversity of South Sumatra, including damar putih, increased to 2,650 trees/seeds, showing a yearly improvement. This indicates that the planting of trees and the conservation of endemic germplasm, specifically damar putih, are effectively implemented.
Propuestos modelos matemáticos originales en probabilidad, sistemas duales y conjetura en primos: para educación, economía, agricultura, finanzas y tecnología
Authors: Massa Fernando Gustavo Isa
Published: September 2023

Se presentan dos teoremas y una conjetura en números primos para ser evaluada por la comunidad científica internacional. Los teoremas son: probabilidad ambigua en inteligencia artificial y sistemas duales donde se introduce y demuestra la ecuación madre de sistemas. Las aplicaciones son diversas, eligiéndose para la investigación: economía y finanzas, educación, agricultura, tecnología y seguridad ciudadana. La razón de estas derivaciones de los modelos originales es la utilidad y la necesidad de los casos. Se tienen como evidencia científica las simulaciones en Excel como datos estadísticos de la web. Los teoremas son demostrados empíricamente y se introducen secciones como: objeto y conclusión a cada teorema. También, se introducen corolarios a cada teorema para darle una forma más abstracta y reforzar las demostraciones planteadas.
STUDIES ON CENTIPEDE ECOLOGY (MYRIAPODA: CHILOPODA) A BIBLIOMETRIC REVIEW
Authors: Ion Constanța-Mihaela , Murariu Dumitru T.
Published: September 2023

As predatory soil macroinvertebrates, centipedes are often considered groups used for soil community studies. However, research explicitly targeting centipede ecology remains relatively scarce. This paper addresses this gap by conducting a formal literature review and scientometric analysis of worldwide publications on the ecology of centipedes, specifically focusing on research studies conducted in Romania. We utilized articles published after 1990 and available in Web of Science collections under Ecology Research Area. As supported by the authors’ keywords co-citation networks, classical aspects of centipedes ecology, such as environmental requirements and tolerances of a particular species, seem to be hidden mainly within taxonomy and faunistic papers. Community ecology approaches are better delimited under the umbrella of biodiversity. Among these, ecotoxicology and food webs topics stand out, the latter being the subject of some of the most cited papers. The study also investigated collaboration groups and the countries supporting research in the field of centipede ecology. In Romania, Zachiu Matic studied the altitudinal distribution of centipedes in two mountain ranges, providing valuable insights into elevation limits for certain species. Additionally, Matic discussed synecological data on centipede communities in oak forests. Another researcher, Radu Gava, compared centipede diversity in different forest types, including oak, beech, and alder forests. Overall, the analysis revealed that the growth of articles on the ecology of centipedes had not followed a growing trend over the years, both internationally and locally. This stagnation suggests that certain limitations may still hinder research development in this field. However, the study sheds light on the existing research landscape and highlights specific areas for further investigation.
VALORIZATION OF DATE WASTE (HMIRA CULTIVAR) FOR THE PRODUCTION OF BIOALCOHOL AND BIOGAS
Authors: Arroussi Abdelaziz , Tahri Ahmed , Nehar Oussama Kheirddine , Soulimani Ahmed El-Amine , Dahou Mohammed El-Amine
Published: September 2023

During the past years, bioethanol and biogas have a significantly development, they are fuels obtained from the fermentation of sugar plants and anaerobic digestion of organic compounds respectively, The major advantage of these biofuels is the reduction of gases Global Warming effect. In this work, two steps were performed: the first was the production of bioethanol from date waste by the fermentation. In the second stage, anaerobic digestion experiments are contucted in four digesters, each with a one litre capacity and a working volume of 600 mL. The digstion pricess takes place at 37°C for a duration of 45 days. To prepare the digesters, 10 g of volatile solids (VS) from the substrate are used. Alkaline pretreatment is employed with NaOH concentrations of 6%, 12%, and 18% (weight/weight, w/w) based on the substrate’s volatile solids (VS). We obtained a yield of 360 mL of bioethanol of 93 ° per 1 kg of date waste. For the anaerobic digestion, the obtained results show that a 12% NaOH is the best concentration with a 1178 mL CH4/gVS.
Türkiye’deki Yabancı Uyruklu Üniversite Öğrencilerinin Stresle Baş Etmelerinde Din ve Maneviyatın Rolüne Yönelik Görüşleri: Nitel Bir Çalışma/ Foreign University Students' Opinions on The Role of Religion and Spirituality in Coping with Stress in Turkey: A Qualitative Study
Authors: UZUN Sevda , ASLAN Çimen
Published: September 2023

Bu çalışma Türkiye’deki yabancı uyruklu üniversite öğrencilerinin stresle baş etmelerinde din ve maneviyatın etkisine yönelik görüşlerini belirlemeyi amaçlamaktadır. Bu araştırmada nitel araştırma desenlerinden fenomenolojik araştırma deseni kullanılmıştır. Araştırma 65 gönüllü yabancı öğrenci ile yürütülmüştür. Görüşmeler bireysel olarak ve yüz yüze gerçekleştirilmiştir. Veriler, Colaizzi'nin fenomenolojik analiz yöntemi kullanılarak analiz edilmiştir. Verilerin analizinde dört kategori (stresle baş etmede maneviyatın katkısına yönelik düşünceler, yabancı uyruklu öğrenci olmaktan dolayı yaşanan sorunlar, maneviyatla ilgili yaşanan sorunlar ve ruh sağlığına yönelik uygulamalar) on bir alt tema (ruhsal, sosyal, fiziksel, iletişim/ortam, kişiler, ortam, kişiler, sosyal, fiziksel ve ruhsal) saptanmıştır. Öğrencilerin yaşadıkları zorluklarla mücadele etmeleri ve strese baş etmelerinde din ve maneviyatın çok önemli olduğu belirlenmiştir. Yabancı uyruklu öğrencilerin birçoğunun dini anlamda sorun yaşamadığı fakat maneviyatla ilgili sorunlar yaşadıkları belirlenmiştir. Ayrıca öğrencilerin farklı bir ülkede yaşmaktan dolayı bazen yalnızlık hissettiği ve dışlanma yaşadığı bulgulanmıştır. Yabancı uyruklu öğrencilerin ruh sağlığını korumak ve geliştirmek için ailelerinden sosyal destek aldığı, sosyal aktiviteler ve dini uygulamalar yaptığı belirlenmiştir.