bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 2 from Characteristics of Lung Cancers Harboring NRAS Mutations
Authors: Ohashi Kadoaki , Sequist Lecia V. , Arcila Maria E. , Lovly Christine M. , Chen Xi , Rudin Charles M. , Moran Teresa , Camidge David Ross , Vnencak-Jones Cindy L. , Berry Lynne , Pan Yumei , Sasaki Hidefumi , Engelman Jeffrey A. , Garon Edward B. , Dubinett Steven M. , Franklin Wilbur A. , Riely Gregory J. , Sos Martin L. , Kris Mark G. , Dias-Santagata Dora , Ladanyi Marc , Bunn Paul A. , Pao William
Published: April 2023

PDF file - 67K, Supplemental Table 2. Clinical characteristics associated with NRAS mutant lung cancers.
Supplementary Figure 3 from Overexpression of the Circadian Clock Gene Bmal1 Increases Sensitivity to Oxaliplatin in Colorectal Cancer
Authors: Zeng Zhao-lei , Luo Hui-yan , Yang Jing , Wu Wen-jing , Chen Dong-liang , Huang Peng , Xu Rui-hua
Published: April 2023

PDF file 38K, The specific Bmal1 protein expression by Western blotting for each transformed cell line compared with its control cell line
Supplementary Figure Legends from TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance
Authors: Silwal-Pandit Laxmi , Vollan Hans Kristian Moen , Chin Suet-Feung , Rueda Oscar M. , McKinney Steven , Osako Tomo , Quigley David A. , Kristensen Vessela N. , Aparicio Samuel , Børresen-Dale Anne-Lise , Caldas Carlos , Langerød Anita
Published: April 2023

PDF file - 292KB
Supplementary Figure 2 from Human Breast Cancer Cells Harboring a Gatekeeper T798M Mutation in HER2 Overexpress EGFR Ligands and Are Sensitive to Dual Inhibition of EGFR and HER2
Authors: Rexer Brent N. , Ghosh Ritwik , Narasanna Archana , Estrada Mónica Valeria , Chakrabarty Anindita , Song Youngchul , Engelman Jeffrey A. , Arteaga Carlos L.
Published: April 2023

Supplementary Figure 2 - PDF file 141K, Expression of T798M HER2 results in increased HER3 phosphorylation and HER3-p85 association
Supplementary Figure 3 from CD62L as a Therapeutic Target in Chronic Lymphocytic Leukemia
Authors: Burgess Melinda , Gill Devinder , Singhania Richa , Cheung Catherine , Chambers Lynne , Renyolds Brent A. , Smith Louise , Mollee Peter , Saunders Nicholas , McMillan Nigel AJ
Published: April 2023

Supplementary Figure 3 - PDF files 1469K, Correlation of CD62L antibody toxicity and clinical parameters
Supplementary Table 1 from Frequent Overexpression of HMGA2 in Human Atypical Teratoid/Rhabdoid Tumor and Its Correlation with let-7a3/let-7b miRNA
Authors: Zhang Keqiang , Gao Hanlin , Wu Xiwei , Wang Jinhui , Zhou Wendi , Sun Guihua , Wang Jinghan , Wang Yafan , Mu Bing , Kim Charles , Chu Peiguo , Ho Donald M. , Ann David K. , Wong Tai-Tong , Yen Yun
Published: April 2023

PDF file - 72K, Table S1. Genetic alterations and protein expression of the SMARCB1 and HMGA2 in AT/RT patients.
Supplementary Figure 3 from Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer
Authors: Wojtalla Anna , Fischer Barbara , Kotelevets Nataliya , Mauri Francesco A. , Sobek Jens , Rehrauer Hubert , Wotzkow Carlos , Tschan Mario P. , Seckl Michael J. , Zangemeister-Wittke Uwe , Arcaro Alexandre
Published: April 2023

PDF file - 1196K, PI3K inhibition reduces vascularization in vivo
Supplementary Figure 3 from PIK3CA Mutation Is Associated with a Favorable Prognosis among Patients with Curatively Resected Esophageal Squamous Cell Carcinoma
Authors: Shigaki Hironobu , Baba Yoshifumi , Watanabe Masayuki , Murata Asuka , Ishimoto Takatsugu , Iwatsuki Masaaki , Iwagami Shiro , Nosho Katsuhiko , Baba Hideo
Published: April 2023

PDF File - 127K, K-M curves in cases without preoperative treatment (left panel) and in cases with preoperative treatment (right panel).
Supplementary Figure 1 from First-in-Human Phase I Trial of Two Schedules of OSI-930, a Novel Multikinase Inhibitor, Incorporating Translational Proof-of-Mechanism Studies
Authors: Yap Timothy A. , Arkenau Hendrik-Tobias , Camidge D. Ross , George Suzanne , Serkova Natalie J. , Gwyther Stephen J. , Spratlin Jennifer L. , Lal Rohit , Spicer James , Desouza Nandita M. , Leach Martin O. , Chick Jon , Poondru Srinivasu , Boinpally Ramesh , Gedrich Richard , Brock Katie , Stephens Andrew , Eckhardt S. Gail , Kaye Stan B. , Demetri George , Scurr Michelle
Published: April 2023

PDF file - 58K, Changes in plasma sVEGFR2 over time in BID cohorts
Supplementary Figure 4 from Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin
Authors: Remark Romain , Alifano Marco , Cremer Isabelle , Lupo Audrey , Dieu-Nosjean Marie-Caroline , Riquet Marc , Crozet Lucile , Ouakrim Hanane , Goc Jeremy , Cazes Aurélie , Fléjou Jean-François , Gibault Laure , Verkarre Virginie , Régnard Jean-François , Pagès Olivier-Nicolas , Oudard Stéphane , Mlecnik Bernhard , Sautès-Fridman Catherine , Fridman Wolf-Herman , Damotte Diane
Published: April 2023

PDF file - 88K, Gene expression in lung metastases from CRC and RCC. Expression of genes related to (a) immune cell populations, (b) Th1/Th2 orientations, (c) inflammation and angiogenesis, (d) immunosuppression, (e) cytotoxicity, (f) chemokines/chemokine receptors in lung metastases from CRC (grey bars) and RCC (white bars). Expression levels of genes were determined using threshold cycle (Ct) values normalized to actin B ACTB (ΔCt). Whiskers length represents 10-90 percentile. ns, not significant; *P<0.05, **P<0.001, ***P<0.0001 (Mann-Whitney test).
Supplementary Figure Legends from Lamin B1 Is a Novel Therapeutic Target of Betulinic Acid in Pancreatic Cancer
Authors: Li Lei , Du Yiqi , Kong Xiangyu , Li Zhaoshen , Jia Zhiliang , Cui Jiujie , Gao Jun , Wang Guokun , Xie Keping
Published: April 2023

Supplementary Figure Legends - PDF file 93K, Supplementary Figure Legends contain 5 figures: Supplementary Fig. S1. Gene expression profiling in pancreatic cancer cells treated with BA. Supplementary Fig. S2. Inhibition of the in vitro and in vivo growth of primary pancreatic cancer cultures and xenografts. Supplementary Fig. S3. Lamin B1 expression pattern in pancreatic tissue. Supplementary Fig. S4. Lamin B1 expression on the nuclear envelop from nuclei with different sizes. Supplementary Fig. S5. Altered lamin B1 expression affect cell cycle progression of pancreatic cancer cells
Supplementary Figure Legend from High Phospho-Stathmin(Serine38) Expression Identifies Aggressive Endometrial Cancer and Suggests an Association with PI3K Inhibition
Authors: Wik Elisabeth , Birkeland Even , Trovik Jone , Werner Henrica M.J. , Hoivik Erling A. , Mjos Siv , Krakstad Camilla , Kusonmano Kanthida , Mauland Karen , Stefansson Ingunn M. , Holst Frederik , Petersen Kjell , Oyan Anne M. , Simon Ronald , Kalland Karl H. , Ricketts William , Akslen Lars A. , Salvesen Helga B.
Published: April 2023

PDF file - 52K
Supplementary Figure S2 from Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer
Authors: Iwaya Takeshi , Fukagawa Takeo , Suzuki Yutaka , Takahashi Yusuke , Sawada Genta , Ishibashi Masahisa , Kurashige Junji , Sudo Tomoya , Tanaka Fumiaki , Shibata Kohei , Endo Fumitaka , Katagiri Hirokatsu , Ishida Kaoru , Kume Kohei , Nishizuka Satoshi , Iinuma Hisae , Wakabayashi Go , Mori Masaki , Sasako Mitsuru , Mimori Koshi
Published: April 2023

PDF file 1870K, The association between histone mRNA and miR-760 in GC cells
Supplementary Table 3 from Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
Authors: Rao Guanhua , Wang Hongyi , Li Baowei , Huang Li , Xue Danfeng , Wang Xiaohui , Jin Haijing , Wang Jun , Zhu Yushan , Lu Youyong , Du Lei , Chen Quan
Published: April 2023

XLSX file - 212K, Correlation between CD68 and OPN in primary colorectal cancer
Supplementary Figure 7 from Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
Authors: Rao Guanhua , Wang Hongyi , Li Baowei , Huang Li , Xue Danfeng , Wang Xiaohui , Jin Haijing , Wang Jun , Zhu Yushan , Lu Youyong , Du Lei , Chen Quan
Published: April 2023

PDF file - 1132K, The promotion of OPN secretion in macrophages by colorectal cancer cells is partially CD44v6 dependent.
Supplementary Figure Legends from Cabozantinib Inhibits Prostate Cancer Growth and Prevents Tumor-Induced Bone Lesions
Authors: Dai Jinlu , Zhang Honglai , Karatsinides Andreas , Keller Jill M. , Kozloff Kenneth M. , Aftab Dana T. , Schimmoller Frauke , Keller Evan T.
Published: April 2023

PDF file 88K, Supplementary Figure Legends
Supplementary Table 3 from Cumulative Genetic Risk Predicts Platinum/Taxane-Induced Neurotoxicity
Authors: McWhinney-Glass Sarah , Winham Stacey J. , Hertz Daniel L. , Yen Revollo Jane , Paul Jim , He Yijing , Brown Robert , Motsinger-Reif Alison A. , McLeod Howard L.
Published: April 2023

PDF file, 75K, Full clinical characteristics of patients from the discovery and replication cohorts.
Supplementary Figures 1 - 5 from Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer
Authors: Torres Sofia , Bartolomé Rubén A. , Mendes Marta , Barderas Rodrigo , Fernandez-Aceñero M. Jesús , Peláez-García Alberto , Peña Cristina , Lopez-Lucendo María , Villar-Vázquez Roi , de Herreros Antonio García , Bonilla Felix , Casal J. Ignacio
Published: April 2023

PDF file - 338K, Supplementary Figures S1 (representation of iTRAQ workflow), S2 (data normalization for iTRAQ analysis), S3 (expression of CAF markers in colorectal tumors in mice), S4 and S5 (correlations of CAF marker expression with clinical data)
Supplementary Table 1 from The ATP-Competitive mTOR Inhibitor INK128 Enhances In Vitro and In Vivo Radiosensitivity of Pancreatic Carcinoma Cells
Authors: Hayman Thomas J. , Wahba Amy , Rath Barbara H. , Bae Heekyong , Kramp Tamalee , Shankavaram Uma T. , Camphausen Kevin , Tofilon Philip J.
Published: April 2023

PDF - 93K, Genes comprising the DNA replication, recombination and repair biological function whose radiation-induced up-regulation was inhibited by INK128.
Supplementary Table 1 from A Genome-Wide Aberrant RNA Splicing in Patients with Acute Myeloid Leukemia Identifies Novel Potential Disease Markers and Therapeutic Targets
Authors: Adamia Sophia , Haibe-Kains Benjamin , Pilarski Patrick M. , Bar-Natan Michal , Pevzner Samuel , Avet-Loiseau Herve , Lode Laurence , Verselis Sigitas , Fox Edward A. , Burke John , Galinsky Ilene , Dagogo-Jack Ibiayi , Wadleigh Martha , Steensma David P. , Motyckova Gabriela , Deangelo Daniel J. , Quackenbush John , Stone Richard , Griffin James D.
Published: April 2023

PDF file - 96K, Characteristics of the patients that were analyzed on the exon arrays.
Supplementary Figure 2A from Preclinical and Early Clinical Evaluation of the Oral AKT Inhibitor, MK-2206, for the Treatment of Acute Myelogenous Leukemia
Authors: Konopleva Marina Y. , Walter Roland B. , Faderl Stefan H. , Jabbour Elias J. , Zeng Zhihong , Borthakur Gautam , Huang Xuelin , Kadia Tapan M. , Ruvolo Peter P. , Feliu Jennie B. , Lu Hongbo , Debose LaKiesha , Burger Jan A. , Andreeff Michael , Liu Wenbin , Baggerly Keith A. , Kornblau Steven M. , Doyle L. Austin , Estey Elihu H. , Kantarjian Hagop M.
Published: April 2023

PDF file - 109KB, Effects of MK-2206 on cell growth and survival of human AML cell lines.
Supplementary Figure Legend from MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer
Authors: Yu San-Jian , Hu Jing-Ying , Kuang Xia-Ying , Luo Jian-Min , Hou Yi-Feng , Di Gen-Hong , Wu Jiong , Shen Zhen-Zhou , Song Hou-Yan , Shao Zhi-Ming
Published: April 2023

PDF file - 61K
Supplementary Data 1 from Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma
Authors: Grupp Stephan A. , Prak Eline Luning , Boyer Jean , McDonald Kenyetta R. , Shusterman Suzanne , Thompson Edward , Callahan Colleen , Jawad Abbas F. , Levine Bruce L. , June Carl H. , Sullivan Kathleen E.
Published: April 2023

PDF file - 405K, Detailed flow cytometric analysis of expanded cells from children and adults
Supplementary Methods from Tumor Genetic Analyses of Patients with Metastatic Renal Cell Carcinoma and Extended Benefit from mTOR Inhibitor Therapy
Authors: Voss Martin H. , Hakimi A. Ari , Pham Can G. , Brannon A. Rose , Chen Ying-Bei , Cunha Luis F. , Akin Oguz , Liu Han , Takeda Shugaku , Scott Sasinya N. , Socci Nicholas D. , Viale Agnes , Schultz Nikolaus , Sander Chris , Reuter Victor E. , Russo Paul , Cheng Emily H. , Motzer Robert J. , Berger Michael F. , Hsieh James J.
Published: April 2023

PDF file - 132K
Supplementary Materials and Methods, Figures 1 - 9, Tables 1 - 7 from Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target
Authors: Chen Guo , Chakravarti Nitin , Aardalen Kimberly , Lazar Alexander J. , Tetzlaff Michael T. , Wubbenhorst Bradley , Kim Sang-Bae , Kopetz Scott , Ledoux Alicia A. , Gopal Y.N. Vashisht , Pereira Cristiano Goncalves , Deng Wanleng , Lee Ju-Seog , Nathanson Katherine L. , Aldape Kenneth D. , Prieto Victor G. , Stuart Darrin , Davies Michael A.
Published: April 2023

PDF file - 416KB, Supplementary methods, figures and tables. Fig. S1. Gene expression profiling of patient-matched brain and extracranial metastases. Fig. S2. PTEN gene expression in BM_03 (homozygous copy loss) and EM_03 (one copy loss). Gene expression was measured by microarray. Fig. S3. Quantitative RT-PCR measurement of SGK3, SGSM2, and ELOVL2 expression in five pairs of brain metastases (BM) and extracranial metastases (EM). Fig. S4. Log2 expression levels of RB_pS807_S811 in seven pairs of matched metastases. Fig. S5 Examples of PTEN-absent tumors. PTEN IHC of BM_03 and EM_03 were photographed at 00X magnification. Fig. S6 GSK3/_pS21/S9 IHC staining in 26 pairs of matched brain metastases (BM) and extracranial metastases (EM). Fig. S7. Results of RB_pS807_S811 IHC in 25 pairs of matched brain metastases (BM) and extracranial metastases (EM). Fig. S8. Kaplan-Meier survival analysis of nude mice with BRAF-mutant melanoma brain metastases treated with BKM120 and/or LGX818. Fig. S9. AKT_pS473 level in subcutaneously (sc) and intracranially (ic) implanted melanomas. Table S1. List of clinical samples analyzed. Table S2. Clinical features and genetic aberrations of matched samples analyzed by high-throughput techniques. Table S3. Hotspot mutations analyzed by Sequenom. Table S4. Antibodies used in RPPA analysis. Table S5. Genes with copy number differences (P <0.05) between matched brain metastases (N =10) and extracranial metastases (N =10). Table S6 CNVs in 13 melanoma-related genes in 10 pairs of matched metastases. Table S7. Genes differently expressed between six pairs of matched brain and extracranial metastases (P<0.01).
Supplementary Figure 4 from Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma
Authors: Rader JulieAnn , Russell Mike R. , Hart Lori S. , Nakazawa Michael S. , Belcastro Lili T. , Martinez Daniel , Li Yimei , Carpenter Erica L. , Attiyeh Edward F. , Diskin Sharon J. , Kim Sunkyu , Parasuraman Sudha , Caponigro Giordano , Schnepp Robert W. , Wood Andrew C. , Pawel Bruce , Cole Kristina A. , Maris John M.
Published: April 2023

Supplementary Figure 4 - PDF file 88K, Protein level expression of FOXM1 in neuroblastoma
Supplementary Figure 2 from The Use of Quantitative Real-Time Reverse Transcriptase PCR for 5′ and 3′ Portions of ALK Transcripts to Detect ALK Rearrangements in Lung Cancers
Authors: Wang Rui , Pan Yunjian , Li Chenguang , Hu Haichuan , Zhang Yang , Li Hang , Luo Xiaoyang , Zhang Jie , Fang Zhaoyuan , Li Yuan , Shen Lei , Ji Hongbin , Garfield David , Sun Yihua , Chen Haiquan
Published: April 2023

PDF file, 12461K, Immunohistochemical staining patterns.
Supplementary Figure 7 from The Nedd8-Activating Enzyme Inhibitor MLN4924 Thwarts Microenvironment-Driven NF-κB Activation and Induces Apoptosis in Chronic Lymphocytic Leukemia B Cells
Authors: Godbersen J. Claire , Humphries Leigh Ann , Danilova Olga V. , Kebbekus Peter E. , Brown Jennifer R. , Eastman Alan , Danilov Alexey V.
Published: April 2023

Effect of MLN4924 on Bim expression in CLL. CLL cells were co-cultured with CD40L-expressing stroma for 24 hours, followed by incubation with 1 ÃŽÂ¼M MLN4924 or vehicle control. Cell were lysed at 24 hours and subjected to immunoblotting. Raji cells (American Type Culture Collection) were cultured in RPMI 1640 with 10% FBS without (first lane) or with (second lane) 50 ÃŽÂ¼g/L phorbol 12-myristate 13-acetate for 30 min to serve as control for expression of phospho-Bim.
Supplementary Methods and Figure Legend from Systemic Administration of a Novel Immune-Stimulatory Pseudovirion Suppresses Lung Metastatic Melanoma by Regionally Enhancing IFN-γ Production
Authors: Saga Kotaro , Tamai Katsuto , Yamazaki Takehiko , Kaneda Yasufumi
Published: April 2023

PDF file - 133K
Supplementary Figure 7 from Systemic Administration of a Novel Immune-Stimulatory Pseudovirion Suppresses Lung Metastatic Melanoma by Regionally Enhancing IFN-γ Production
Authors: Saga Kotaro , Tamai Katsuto , Yamazaki Takehiko , Kaneda Yasufumi
Published: April 2023

PDF file - 137K, Measurement of scIL-12-HVJ-E-mediated CTL activation in the mice bearing lung metastases following treatment with the IFN-γ-neutralizing antibody.
Supplementary Methods, Tables 1 - 2 from Phase I Dose-Escalation Study of Onartuzumab as a Single Agent and in Combination with Bevacizumab in Patients with Advanced Solid Malignancies
Authors: Salgia Ravi , Patel Premal , Bothos John , Yu Wei , Eppler Steve , Hegde Priti , Bai Shuang , Kaur Surinder , Nijem Ihsan , Catenacci Daniel V.T. , Peterson Amy , Ratain Mark J. , Polite Blase , Mehnert Janice M. , Moss Rebecca A.
Published: April 2023

PDF file - 88K, Table S1. Treatment-related adverse events across all dosing cohorts in Phase Ia escalation and expansion, and Phase Ib. Table S2. Most commonly reported adverse events regardless of relationship to study drug.
Supplementary Figure 1 from hTERT Inhibition Triggers Epstein–Barr Virus Lytic Cycle and Apoptosis in Immortalized and Transformed B Cells: A Basis for New Therapies
Authors: Giunco Silvia , Dolcetti Riccardo , Keppel Sonia , Celeghin Andrea , Indraccolo Stefano , Dal Col Jessica , Mastorci Katy , De Rossi Anita
Published: April 2023

PDF file - 23K, hTERT and BATF expression.
Supplementary Table 1 from A Phase I Study of an Agonist CD40 Monoclonal Antibody (CP-870,893) in Combination with Gemcitabine in Patients with Advanced Pancreatic Ductal Adenocarcinoma
Authors: Beatty Gregory L. , Torigian Drew A. , Chiorean E. Gabriela , Saboury Babak , Brothers Alex , Alavi Abass , Troxel Andrea B. , Sun Weijing , Teitelbaum Ursina R. , Vonderheide Robert H. , O'Dwyer Peter J.
Published: April 2023

Supplementary Table 1 - PDF file 56K, Spearman Rank Correlation Analysis of Biomarkers for Overall Survival
Supplementary Table 3 from Phase I Studies of Sirolimus Alone or in Combination with Pharmacokinetic Modulators in Advanced Cancer Patients
Authors: Cohen Ezra E.W. , Wu Kehua , Hartford Christine , Kocherginsky Masha , Eaton Kimberly Napoli , Zha Yuanyuan , Nallari Anitha , Maitland Michael L. , Fox-Kay Kammi , Moshier Kristin , House Larry , Ramirez Jacqueline , Undevia Samir D. , Fleming Gini F. , Gajewski Thomas F. , Ratain Mark J.
Published: April 2023

PDF file - 38K, Change in sirolimus Cmax and AUC with or without ketoconazole and grapefruit juice by dose level by a non-compartmental analysis
Supplementary Table 2 from Phase I Studies of Sirolimus Alone or in Combination with Pharmacokinetic Modulators in Advanced Cancer Patients
Authors: Cohen Ezra E.W. , Wu Kehua , Hartford Christine , Kocherginsky Masha , Eaton Kimberly Napoli , Zha Yuanyuan , Nallari Anitha , Maitland Michael L. , Fox-Kay Kammi , Moshier Kristin , House Larry , Ramirez Jacqueline , Undevia Samir D. , Fleming Gini F. , Gajewski Thomas F. , Ratain Mark J.
Published: April 2023

PDF file - 36K, Patient Characteristics
Supplementary Table S1 from Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer
Authors: Zhang Geng , He Peijun , Tan Hanson , Budhu Anuradha , Gaedcke Jochen , Ghadimi B. Michael , Ried Thomas , Yfantis Harris G. , Lee Dong H. , Maitra Anirban , Hanna Nader , Alexander H. Richard , Hussain S. Perwez
Published: April 2023

Supplementary Table S1 - PDF file 67K, Characteristics of Patients
Supplementary Methods from CD44 and OTP Are Strong Prognostic Markers for Pulmonary Carcinoids
Authors: Swarts Dorian R.A. , Henfling Mieke E.R. , Van Neste Leander , van Suylen Robert-Jan , Dingemans Anne-Marie C. , Dinjens Winand N.M. , Haesevoets Annick , Rudelius Martina , Thunnissen Erik , Volante Marco , Van Criekinge Wim , van Engeland Manon , Ramaekers Frans C.S. , Speel Ernst-Jan M.
Published: April 2023

PDF file - 121K
Supplementary Methods, Figure Legends 1-6 from The CXCL12–CXCR4 Chemokine Pathway: A Novel Axis Regulates Lymphangiogenesis
Authors: Zhuo Wei , Jia Lin , Song Nan , Lu Xin-an , Ding Yanping , Wang Xiaofeng , Song Xiaomin , Fu Yan , Luo Yongzhang
Published: April 2023

PDF file - 166K
Supplementary Table S1 from Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation
Authors: Martin Eric S. , Belmont Peter J. , Sinnamon Mark J. , Richard Larissa Georgeon , Yuan Jing , Coffee Erin M. , Roper Jatin , Lee Lydia , Heidari Pedram , Lunt Sophia Y. , Goel Gautam , Ji Xiadong , Xie Zhi , Xie Tao , Lamb John , Weinrich Scott L. , VanArsdale Todd , Bronson Roderick T. , Xavier Ramnik J. , Vander Heiden Matthew G. , Kan Julie L. C. , Mahmood Umar , Hung Kenneth E.
Published: April 2023

XLS file - 34 KB, Differentially expressed genes in GEMM AP vs AKP
Supplementary Figures 1 - 6 from P-Glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain and Blood Disposition of the mTOR Inhibitor Everolimus (Afinitor) in Mice
Authors: Tang Seng Chuan , Sparidans Rolf W. , Cheung Ka Lei , Fukami Tatsuki , Durmus Selvi , Wagenaar Els , Yokoi Tsuyoshi , van Vlijmen Bart J.M. , Beijnen Jos H. , Schinkel Alfred H.
Published: April 2023

PDF file - 666KB, S1. Molecular structure of everolimus (A) and putative molecular structure of metabolite A (B). S2. 2. Liver expression of Ces1 and Ces2 genes in male wild-type, Abcb1a/1b(-/-), Abcg2(-/-) and Abcb1a/1b;Abcg2(-/-) mice. S3. Inhibitory effect of everolimus on the conversion of irinotecan to SN-38 by Ces1c in male wild-type and knockout mouse plasmas in vitro. S4. Blood concentration-time curves of everolimus in male wild-type, Abcb1a/1b(-/-), Cyp3a(-/-) and Abcb1a/1b. Cyp3a(-/-) mice receiving oral everolimus (2 mg/kg). S5. Schematic model of the envisaged effect of Ces1c on the stability and degradation of everolimus in plasma. S6. Semi-synthetic diet does not prevent altered everolimus pharmacokinetics.
Supplementary Table 1 from Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer
Authors: Chittaranjan Suganthi , Bortnik Svetlana , Dragowska Wieslawa H. , Xu Jing , Abeysundara Namal , Leung Amy , Go Nancy E. , DeVorkin Lindsay , Weppler Sherry A. , Gelmon Karen , Yapp Donald T. , Bally Marcel B. , Gorski Sharon M.
Published: April 2023

Inhibitory activity of anthracyclines and their analogs on sensitive and resistant TNBC cells.
Supplementary Figure 5 from Functional Genetic Screens Identify Genes Essential for Tumor Cell Survival in Head and Neck and Lung Cancer
Authors: Martens-de Kemp Sanne R. , Nagel Remco , Stigter-van Walsum Marijke , van der Meulen Ida H. , van Beusechem Victor W. , Braakhuis Boudewijn J.M. , Brakenhoff Ruud H.
Published: April 2023

PDF file - 43K, KIF11 protein expression in NSCLC and HNSCC cell lines.
Supplementary Figure legends-S1-6 from ASS1 as a Novel Tumor Suppressor Gene in Myxofibrosarcomas: Aberrant Loss via Epigenetic DNA Methylation Confers Aggressive Phenotypes, Negative Prognostic Impact, and Therapeutic Relevance
Authors: Huang Hsuan-Ying , Wu Wen-Ren , Wang Yu-Hui , Wang Jun-Wen , Fang Fu-Min , Tsai Jen-Wei , Li Shau-Hsuan , Hung Hsiao-Chin , Yu Shih-Chen , Lan Jui , Shiue Yow-Ling , Hsing Chung-His , Chen Li-Tzong , Li Chien-Feng
Published: April 2023

Supplementary Figure legends-S1-6 PDF file 207K, The file contains legends for Supplementary Figure S1-6
Supplementary Table 2 from Number of Target Lesions for EASL and Modified RECIST to Predict Survivals in Hepatocellular Carcinoma Treated with Chemoembolization
Authors: Kim Beom Kyung , Kim Seung Up , Kim Myeong-Jin , Kim Kyung Ah , Kim Do Young , Park Jun Yong , Ahn Sang Hoon , Han Kwang-Hyub , Chon Chae Yoon
Published: April 2023

PDF file - 136K, Univariate analysis for parameters influencing overall survival
Supplementary Document 3 from Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
Authors: Fjeldbo Christina S. , Julin Cathinka H. , Lando Malin , Forsberg Malin F. , Aarnes Eva-Katrine , Alsner Jan , Kristensen Gunnar B. , Malinen Eirik , Lyng Heidi
Published: April 2023

Comparing our 6 classifier genes with published hypoxia gene signatures.
Figure S2 from Interobserver Agreement in Describing the Ultrasound Appearance of Adnexal Masses and in Calculating the Risk of Malignancy Using Logistic Regression Models
Authors: Sladkevicius Povilas , Valentin Lil
Published: April 2023

Figure S2. Relationship between number of days between the two examinations and inter-observer difference in mean tumor diameter of benign and malignant tumors is shown on this scatterplot
Supplementary Table 1 from Functional Genomics Uncover the Biology behind the Responsiveness of Head and Neck Squamous Cell Cancer Patients to Cetuximab
Authors: Bossi Paolo , Bergamini Cristiana , Siano Marco , Cossu Rocca Maria , Sponghini Andrea P. , Favales Federica , Giannoccaro Marco , Marchesi Edoardo , Cortelazzi Barbara , Perrone Federica , Pilotti Silvana , Locati Laura D. , Licitra Lisa , Canevari Silvana , De Cecco Loris
Published: April 2023

Supplementary Table 1. List of the 509 genes differentially expressed between long- and short-PFS patients.
Suppl Fig S1 from Complement Pathway Is Frequently Altered in Endometriosis and Endometriosis-Associated Ovarian Cancer
Authors: Suryawanshi Swati , Huang Xin , Elishaev Esther , Budiu Raluca A. , Zhang Lixin , Kim SungHwan , Donnellan Nicole , Mantia-Smaldone Gina , Ma Tianzhou , Tseng George , Lee Ted , Mansuria Suketu , Edwards Robert P. , Vlad Anda M.
Published: April 2023

Suppl Fig S1. Venn diagram of DE genes from 3 group comparisons
Data Supplement from Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers
Authors: Pickering Curtis R. , Zhang Jiexin , Neskey David M. , Zhao Mei , Jasser Samar A. , Wang Jiping , Ward Alexandra , Tsai C. Jillian , Ortega Alves Marcus V. , Zhou Jane H. , Drummond Jennifer , El-Naggar Adel K. , Gibbs Richard , Weinstein John N. , Wheeler David A. , Wang Jing , Frederick Mitchell J. , Myers Jeffrey N.
Published: April 2023

Supplementary Figure S1. Association between age, number of mutations and smoking status.
Supplementary Table 1 from An Open-Label, Multicenter, Phase I/II Study of JNJ-40346527, a CSF-1R Inhibitor, in Patients with Relapsed or Refractory Hodgkin Lymphoma
Authors: von Tresckow Bastian , Morschhauser Franck , Ribrag Vincent , Topp Max S. , Chien Caly , Seetharam Shobha , Aquino Regina , Kotoulek Sonja , de Boer Carla J. , Engert Andreas
Published: April 2023

Supplementary Table 1: Extent of Exposure
Supplementary Figure 1 Legend from Pilot Clinical Trial of Hedgehog Pathway Inhibitor GDC-0449 (Vismodegib) in Combination with Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma
Authors: Kim Edward J. , Sahai Vaibhav , Abel Ethan V. , Griffith Kent A. , Greenson Joel K. , Takebe Naoko , Khan Gazala N. , Blau John L. , Craig Ronald , Balis Ulysses G. , Zalupski Mark M. , Simeone Diane M.
Published: April 2023

Supplementary Figure 1 Legend. Median overall survival correlated with change in CA 19-9 (>50% decrease, versus {less than or equal to}50% decrease, or primary increase)
Supplementary Table 1 from Calreticulin Promotes Migration and Invasion of Esophageal Cancer Cells by Upregulating Neuropilin-1 Expression via STAT5A
Authors: Shi Feng , Shang Li , Pan Bei-Qing , Wang Xiao-Min , Jiang Yan-Yi , Hao Jia-Jie , Zhang Yu , Cai Yan , Xu Xin , Zhan Qi-Min , Wang Ming-Rong
Published: April 2023

Supplementary Table 1. NRP1 expression positively correlates with CRT in ESCC
Supplementary Figure Legend from Gene Expression Profile Identifies Tyrosine Kinase c-Met as a Targetable Mediator of Antiangiogenic Therapy Resistance
Authors: Jahangiri Arman , De Lay Michael , Miller Liane M. , Carbonell W. Shawn , Hu Yu-Long , Lu Kan , Tom Maxwell W. , Paquette Jesse , Tokuyasu Taku A. , Tsao Sean , Marshall Roxanne , Perry Arie , Bjorgan Kirsten M. , Chaumeil Myriam M. , Ronen Sabrina M. , Bergers Gabriele , Aghi Manish K.
Published: April 2023

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Supplementary Figure 1 from Persistence of CTL Clones Targeting Melanocyte Differentiation Antigens Was Insufficient to Mediate Significant Melanoma Regression in Humans
Authors: Chandran Smita S. , Paria Biman C. , Srivastava Abhishek K. , Rothermel Luke D. , Stephens Daniel J. , Dudley Mark E. , Somerville Robert , Wunderlich John R. , Sherry Richard M. , Yang James C. , Rosenberg Steven A. , Kammula Udai S.
Published: April 2023

Supplementary Figure 1. PET-CT scan images
Supplementary Figure Legends from Dasatinib plus Capecitabine for Advanced Breast Cancer: Safety and Efficacy in Phase I Study CA180004
Authors: Somlo George , Atzori Francesco , Strauss Lewis C. , Geese William J. , Specht Jennifer M. , Gradishar William J. , Rybicki Alissa , Sy Oumar , Vahdat Linda T. , Cortes Javier
Published: April 2023

PDF file - 97 KB
Data Supplement from Clinical Significance of EpCAM mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform
Authors: Guo Wei , Yang Xin-Rong , Sun Yun-Fan , Shen Min-Na , Ma Xiao-Lu , Wu Jiong , Zhang Chun-Yan , Zhou Yan , Xu Yang , Hu Bo , Zhang Xin , Zhou Jian , Fan Jia
Published: April 2023

Supplementary Materials and Methods
Data Supplement from Systematically Defining Single-Gene Determinants of Response to Neoadjuvant Chemotherapy Reveals Specific Biomarkers
Authors: Witkiewicz Agnieszka K. , Balaji Uthra , Knudsen Erik S.
Published: April 2023

Table 1: Clinical Summary Discovery. Table 2: Clinical Summary Validation. Table 3: Clinical Summary IHC Cohort. Table 4: Patient Characteristics Discovery and Validation Cohorts. Figure S1: GGI and CIN70 gene expression signatures were employed to cluster cases in the TA cohort based on its expression values.The Kolmogorov-Smirnov (KS) statistic was used to determine the association of the signature value with clinical response. Figure S2: The indicated gene expression signatures were employed to cluster cases in the TFAC cohort based on its expression values. The Kolmogorov-Smirnov (KS) statistic was used to determine the association of the signature value with clinical response. Figure S3: The indicated gene expression signatures were employed to cluster cases in both ER-positive and ER-negative cohorts independently. The Kolmogorov-Smirnov (KS) statistic was used to determine the association of the signature value with clinical response. Figure S4: The top performing genes associated with pCR and RD; DEK and BCAM respectively, are shown as a single determinant of pathological response in both ER-positive and ER-negative breast cancers. Figure S5: ROC curves showing association between IHC scores and clinical outcomes for BCAM and DEK. Figure S6: The ROC curves of all genes on the Theraprint Diagnostic tool were evaluated in the indicated neoadjuvant cohorts. The AUC is provided for each individual gene.
Supplementary Figure S3 from Treatment with Chemotherapy and Dendritic Cells Pulsed with Multiple Wilms' Tumor 1 (WT1)–Specific MHC Class I/II–Restricted Epitopes for Pancreatic Cancer
Authors: Koido Shigeo , Homma Sadamu , Okamoto Masato , Takakura Kazuki , Mori Masako , Yoshizaki Shinji , Tsukinaga Shintaro , Odahara Shunichi , Koyama Seita , Imazu Hiroo , Uchiyama Kan , Kajihara Mikio , Arakawa Hiroshi , Misawa Takeyuki , Toyama Yoichi , Yanagisawa Satoru , Ikegami Masahiro , Kan Shin , Hayashi Kazumi , Komita Hideo , Kamata Yuko , Ito Masaki , Ishidao Takefumi , Yusa Sei-ichi , Shimodaira Shigetaka , Gong Jianlin , Sugiyama Haruo , Ohkusa Toshifumi , Tajiri Hisao
Published: April 2023

Frequency of regulatory T cells or myeloid-derived suppressor cells in patients before and after therapy.
Supplementary Table 1 from p53 Arg72Pro Polymorphism, HPV Status and Initiation, Progression, and Development of Cervical Cancer: A Systematic Review and Meta-Analysis
Authors: Habbous Steven , Pang Vincent , Eng Lawson , Xu Wei , Kurtz Goldie , Liu Fei-Fei , Mackay Helen , Amir Eitan , Liu Geoffrey
Published: April 2023

PDF file - 136K, Profile of studies used in this meta-analysis. Of the 51 original articles included in this report, 49 are shown here: two were excluded from this table as they did not contribute to any of the main analyses (case-only). Contribution to aims 1-3 are indicated by √ in initiation of carcinogenesis, progression of disease, and overall risk of cervical cancer, respectively.
Supplementary table 6 from Low Cancer Stem Cell Marker Expression and Low Hypoxia Identify Good Prognosis Subgroups in HPV(−) HNSCC after Postoperative Radiochemotherapy: A Multicenter Study of the DKTK-ROG
Authors: Linge Annett , Löck Steffen , Gudziol Volker , Nowak Alexander , Lohaus Fabian , von Neubeck Cläre , Jütz Martin , Abdollahi Amir , Debus Jürgen , Tinhofer Inge , Budach Volker , Sak Ali , Stuschke Martin , Balermpas Panagiotis , Rödel Claus , Avlar Melanie , Grosu Anca-Ligia , Bayer Christine , Belka Claus , Pigorsch Steffi , Combs Stephanie E. , Welz Stefan , Zips Daniel , Buchholz Frank , Aust Daniela E. , Baretton Gustavo B. , Thames Howard D. , Dubrovska Anna , Alsner Jan , Overgaard Jens , Baumann Michael , Krause Mechthild
Published: April 2023

A. Correlation of CSC marker expressions. B. Multivariate analyses of stem cell markers and additional prognostic factors for all patients. HR = hazard ratio; 95% CI = 95 percent confidence interval ; ECE = extracapsular extension. C. Correlation of CSC marker expression and HPV16 DNA.
Supplemental figure 2: Protein expression profiles of key regulators of apoptosis in DLBCL cell lines. from Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma
Authors: Klanova Magdalena , Andera Ladislav , Brazina Jan , Svadlenka Jan , Benesova Simona , Soukup Jan , Prukova Dana , Vejmelkova Dana , Jaksa Radek , Helman Karel , Vockova Petra , Lateckova Lucie , Molinsky Jan , Maswabi Bokang Calvin Lenyeletse , Alam Mahmudul , Kodet Roman , Pytlik Robert , Trneny Marek , Klener Pavel
Published: April 2023

Western blot analysis showing protein expression profile of key regulators of apoptosis in 18 DLBCL cell lines (12 germinal center B-cell-like (GCB) and 6 activated B-cell-like (ABC) DLBCL cell lines). *UPF4D cell line (GCB origin) was derived in our laboratory.
supplementary figure 4 from Primary and Acquired Resistance of Colorectal Cancer to Anti-EGFR Monoclonal Antibody Can Be Overcome by Combined Treatment of Regorafenib with Cetuximab
Authors: Napolitano Stefania , Martini Giulia , Rinaldi Barbara , Martinelli Erika , Donniacuo Maria , Berrino Liberato , Vitagliano Donata , Morgillo Floriana , Barra Giusy , De Palma Raffaele , Merolla Francesco , Ciardiello Fortunato , Troiani Teresa
Published: April 2023

supplementary figure 4. Effects of cetuximab in combination with regorafenib on mice body weight.
Supplemental Methods and Results from First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors
Authors: Starodub Alexander N. , Ocean Allyson J. , Shah Manish A. , Guarino Michael J. , Picozzi Vincent J. , Vahdat Linda T. , Thomas Sajeve S. , Govindan Serengulam V. , Maliakal Pius P. , Wegener William A. , Hamburger Steven A. , Sharkey Robert M. , Goldenberg David M.
Published: April 2023

This file contains additional methods, including eligibility criteria, study design, pharmacokinetics and immunogenicity, and immunohistology, as well as additional results related to several notable patient narratives.
Supplementary Figure 2 from Monoclonal Antibodies Targeting LecLex-Related Glycans with Potent Antitumor Activity
Authors: Chua Jia Xin , Vankemmelbeke Mireille , McIntosh Richard S. , Clarke Philip A. , Moss Robert , Parsons Tina , Spendlove Ian , Zaitoun Abid M. , Madhusudan Srinivasan , Durrant Lindy G.
Published: April 2023

Supplementary Figure 2. containing FG88.2 binding to normal CN monkey TMA and evaluation of FG88.2 binding to PBMCs, granulocytes and erythrocytes. Sandwich ELISA for saliva Lewis a detection.
Supplementary Figures S1-6 from Pharmacologic Inhibition of JAK1/JAK2 Signaling Reduces Experimental Murine Acute GVHD While Preserving GVT Effects
Authors: Carniti Cristiana , Gimondi Silvia , Vendramin Antonio , Recordati Camilla , Confalonieri Davide , Bermema Anisa , Corradini Paolo , Mariotti Jacopo
Published: April 2023

Supplementary Figures S1-6. Figure S1: Histological staging criteria for acute GvHD Figure S2: Ruxolitinib does not impair post-transplant donor myeloid reconstitution and full donor chimerism. Figure S3: GVT effect against myeloid leukemia RMB-1 cell line is maintained in the presence of ruxolitinib Figure S4: Ruxolitinib at the dose of 90 mg/Kg prevents acute GVHD without affecting T cell alloreactivity Figure S5: Ruxolitinib effect at 45 mg/Kg on absolute numbers of alloreactive T cells, Th17 and Treg cells. Figure S6: Representative Images of Ruxolitinb effect on T cells and macrophage infiltration of GVHD organs
Supplemental Section - Clean from Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors
Authors: Von Hoff Daniel D. , Mita Monica M. , Ramanathan Ramesh K. , Weiss Glen J. , Mita Alain C. , LoRusso Patricia M. , Burris Howard A. , Hart Lowell L. , Low Susan C. , Parsons Donald M. , Zale Stephen E. , Summa Jason M. , Youssoufian Hagop , Sachdev Jasgit C.
Published: April 2023

Supplemental Section for Resubmission - Clean Version
Supplementary Figure S2 from Induction of PD-L1 Expression by the EML4–ALK Oncoprotein and Downstream Signaling Pathways in Non–Small Cell Lung Cancer
Authors: Ota Keiichi , Azuma Koichi , Kawahara Akihiko , Hattori Satoshi , Iwama Eiji , Tanizaki Junko , Harada Taishi , Matsumoto Koichiro , Takayama Koichi , Takamori Shinzo , Kage Masayoshi , Hoshino Tomoaki , Nakanishi Yoichi , Okamoto Isamu
Published: April 2023

Supplementary Figure S2. Effects of inhibitors of PI3K-AKT and MEK-ERK signaling on PD-L1 expression in Ba/F3 cells expressing EML4-ALK.
Supplementary Table S2 from Quantifying Treatment Benefit in Molecular Subgroups to Assess a Predictive Biomarker
Authors: Iasonos Alexia , Chapman Paul B. , Satagopan Jaya M.
Published: April 2023

Quantifying treatment benefit in marker specific subgroups. Additional examples and clinical interpretation.
Supplementary Data from Quantifying Treatment Benefit in Molecular Subgroups to Assess a Predictive Biomarker
Authors: Iasonos Alexia , Chapman Paul B. , Satagopan Jaya M.
Published: April 2023

Definitions of treatment benefit and differential treatment benefit, statistical properties of the proposed measures, and additional examples
Supplementary Table S3 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Authors: Klintman Marie , Buus Richard , Cheang Maggie Chon U. , Sheri Amna , Smith Ian E. , Dowsett Mitch
Published: April 2023

Association between DUSP4 expression and Ras-ERK pathway proteins measured by reverse-phase protein arrays (RPPA) in 633 breast tumours from TCGA
Supplementary Table S4. from Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors
Authors: Chen Eddy J. , Sowalsky Adam G. , Gao Shuai , Cai Changmeng , Voznesensky Olga , Schaefer Rachel , Loda Massimo , True Lawrence D. , Ye Huihui , Troncoso Patricia , Lis Rosina L. , Kantoff Philip W. , Montgomery Robert B. , Nelson Peter S. , Bubley Glenn J. , Balk Steven P. , Taplin Mary-Ellen
Published: April 2023

Supplementary Table S4. Mutations found only in block S tumor focus.
Figure S4 from SIRPα-Antibody Fusion Proteins Selectively Bind and Eliminate Dual Antigen-Expressing Tumor Cells
Authors: Piccione Emily C. , Juarez Silvia , Tseng Serena , Liu Jie , Stafford Melissa , Narayanan Cyndhavi , Wang Lijuan , Weiskopf Kipp , Majeti Ravindra
Published: April 2023

Supplementary Figure S4: Pharmacokinetic profiles of rituximab and CD20-2GL-SIRPα HC in NSG mouse models
Supplementary Figure S4 from Personalized Preclinical Trials in BRAF Inhibitor–Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies
Authors: Krepler Clemens , Xiao Min , Sproesser Katrin , Brafford Patricia A. , Shannan Batool , Beqiri Marilda , Liu Qin , Xu Wei , Garman Bradley , Nathanson Katherine L. , Xu Xiaowei , Karakousis Giorgos C. , Mills Gordon B. , Lu Yiling , Ahmed Tamer A. , Poulikakos Poulikos I. , Caponigro Giordano , Boehm Markus , Peters Malte , Schuchter Lynn M. , Weeraratna Ashani T. , Herlyn Meenhard
Published: April 2023

A. immunoblot for BRAF splicing variants B. PCR with primers for BRAF_F/R (Exon1-11).
Supplemental Figure Legends from Novel Actions of Next-Generation Taxanes Benefit Advanced Stages of Prostate Cancer
Authors: de Leeuw Renée , Berman-Booty Lisa D. , Schiewer Matthew J. , Ciment Stephen J. , Den Robert B. , Dicker Adam P. , Kelly William K. , Trabulsi Edouard J. , Lallas Costas D. , Gomella Leonard G. , Knudsen Karen E.
Published: April 2023

Figure legends corresponding with Supplemental Figure 1-6.
Figure S7 from β-Cryptoxanthin Synergistically Enhances the Antitumoral Activity of Oxaliplatin through ΔNP73 Negative Regulation in Colon Cancer
Authors: San Millán Coral , Soldevilla Beatriz , Martín Paloma , Gil-Calderón Beatriz , Compte Marta , Pérez-Sacristán Belén , Donoso Encarnación , Peña Cristina , Romero Jesús , Granado-Lorencio Fernando , Bonilla Félix , Domínguez Gemma
Published: April 2023

Figure S7. (A) Body weight in mice before and after treatment and, (B) clinical biochemical parameters in mice after treatment: alaninetransaminase (ALT), aspartatetransaminase (AST), gamma-glutaminetransferase, creatinin and bilirrubin.
Supplemental Data from Using Whole-Exome Sequencing to Identify Genetic Markers for Carboplatin and Gemcitabine-Induced Toxicities
Authors: Gréen Henrik , Hasmats Johanna , Kupershmidt Ilya , Edsgärd Daniel , de Petris Luigi , Lewensohn Rolf , Blackhall Fiona , Vikingsson Svante , Besse Benjamin , Lindgren Andrea , Brandén Eva , Koyi Hirsh , Peterson Curt , Lundeberg Joakim
Published: April 2023

Supplemental Figure 1. Sets of variants identified with sign test and respective controls in network enrichment analysis. Supplemental Figure 2 - Genes and networks identified in the Network enrichment analysis. Supplemental Table 1 - Exome sequencing results Supplemental Table 2 A-F - Top SNVs for each bioinformatic strategy Supplemental Table 3. Genes selected from a priori knowledge of gemcitabine and carboplatin mechanism of action, transport, and metabolism. Supplemental Table 4. Summary of Ingenuity top pathways Supplemental Table 5. Patient characteristics in the validation set Supplemental Table 6. Genetic variants included in the validation
Additional Table II from Minimal Residual Disease after Conventional Treatment Significantly Impacts on Progression-Free Survival of Patients with Follicular Lymphoma: The FIL FOLL05 Trial
Authors: Galimberti Sara , Luminari Stefano , Ciabatti Elena , Grassi Susanna , Guerrini Francesca , Dondi Alessandra , Marcheselli Luigi , Ladetto Marco , Piccaluga Pier Paolo , Gazzola Anna , Mannu Claudia , Monitillo Luigia , Mantoan Barbara , Del Giudice Ilaria , Della Starza Irene , Cavalli Marzia , Arcaini Luca , Tucci Alessandra , Palumbo Giuseppe Alberto , Rigacci Luigi , Pulsoni Alessandro , Vitolo Umberto , Boccomini Carola , Vallisa Daniele , Bertoldero Giovanni , Gaidano Gianluca , Musto Pellegrino , Petrini Mario , Federico Massimo
Published: April 2023

Cox proportional hazard Models for PFS: role of MRD-negativity after 12 month of follow-up.
Supplementary Figure S4 from The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects
Authors: Shahbazi Jeyran , Liu Pei Y. , Atmadibrata Bernard , Bradner James E. , Marshall Glenn M. , Lock Richard B. , Liu Tao
Published: April 2023

JQ1 and panobinostat do not cooperatively induce apoptosis in normal non-malignant cells.
Supplementary Figure1 from Reduced Expression of SMAD4 Is Associated with Poor Survival in Colon Cancer
Authors: Yan Pu , Klingbiel Dirk , Saridaki Zenia , Ceppa Paola , Curto Monica , McKee Thomas Alexander , Roth Arnaud , Tejpar Sabine , Delorenzi Mauro , Bosman Fredrik T. , Fiocca Roberto
Published: April 2023

Correlation was shown between SMAD4 mRNA expression (gene expression data) and protein expression (IHC).
Supplemental Figure S1 from Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling
Authors: Bowers Jacob S. , Nelson Michelle H. , Kundimi Sreenath , Bailey Stefanie R. , Huff Logan W. , Schwartz Kristina M. , Cole David J. , Rubinstein Mark P. , Paulos Chrystal M.
Published: April 2023

Supplemental Figure S1. Infiltration of pmel-1 Tc0 and Tc17 cells in the tumor is enhanced by TBI in dose dependent manner over host cells. C57BL/6 mice were injected with 3x105 B16F10 melanoma.
Supplementary Figure 1 from Detection and Dynamic Changes of EGFR Mutations from Circulating Tumor DNA as a Predictor of Survival Outcomes in NSCLC Patients Treated with First-line Intercalated Erlotinib and Chemotherapy
Authors: Mok Tony , Wu Yi-Long , Lee Jin Soo , Yu Chong-Jen , Sriuranpong Virote , Sandoval-Tan Jennifer , Ladrera Guia , Thongprasert Sumitra , Srimuninnimit Vichien , Liao Meilin , Zhu Yunzhong , Zhou Caicun , Fuerte Fatima , Margono Benjamin , Wen Wei , Tsai Julie , Truman Matt , Klughammer Barbara , Shames David S. , Wu Lin
Published: April 2023

Supplementary Figure 1. (A) PFS in the cfDNA mut+ subgroup (B) OS in the cfDNA mut+ subgroup (C) PFS in the cfDNA mut+ subgroup (patients with no tissue result) (D) OS in the cfDNA mut+ subgroup (patients with no tissue result) (E) PFS in the cfDNA mut- subgroup (F) OS in the cfDNA mut- subgroup (G) PFS in the cfDNA mut- subgroup (no tissue result )(H) OS in the cfDNA mut- subgroup (no tissue result)