bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects on the ATP Content of Cultured Cells after Radiographic Contrast Media Exposure
Authors: Nordby A. , Thorstensen K. , Halgunset J. , Haugen O. A. , Solberg S.
Published: June 2015

The ATP content of cultured cells after exposure to meglumine-calcium metrizoate, sodium metrizoate, iohexol, iopamidol and saline was studied. Initially, the ATP content diminished rapidly for a short period and thereafter slowly during the incubation. After incubation with contrast media or saline, the ATP content slowly increased to normal when the cells were reincubated with fresh nutrient medium. Different contrast media and saline with the same final osmolality produced a similar effect on the ATP content of the cultured cells. Cellular association of meglumine-sodium diatrizoate, sodium metrizoate, sodium-iothalamate, iohexol and iopamidol was also examined. The established cell line NHIK 3025 as well as primary cultures of human umbilical endothelium were found to accumulate contrast media in a time-and concentration-dependent manner. When the incubation was carried out at 4°C, the cellular accumulation of contrast medium was less than 35 per cent of that seen at 37°C. It therefore seems that energy-dependent processes are involved to some degree.
Effect of Contrast Media on Left Ventricular Function during Left Coronary Arteriography in Dogs
Authors: Hayakawa K. , Yamashita K.
Published: June 2015

The effect of contrast media on the left ventricular function of the heart was assessed by left coronary administration of contrast media using canine models. Following insertion of the catheter into the left coronary artery, 0.5 ml/kg of a test solution was injected at a rate of 1 ml/s. The test solutions included isotonic saline, meglumine/sodium diatrizoate, iopamidol and ioxaglate. The mean systemic pressure, left ventricular end-systolic and end-diastolic pressures and the first derivative of left ventricular pressure were continuously measured until five min post-injection. Left ventricular function decreased immediately by 15 s post-injection and recovered quickly by one min. The inhibition of myocardial contractility was observed with diatrizoate and ioxaglate to the same degree. These changes were statistically more pronounced than those with iopamidol, which showed changes similar to those with saline in all parameters except for the positive inotropic effects. These observations suggest that not only hyperosmolality but also ionic composition and chemotoxicity are the factors responsible for the myocardial depression and that no single factor dominates in their effects.
Changes in Atrial Natriuretic Peptide Concentration at Femoral Arteriography in Man
Authors: Sörensen L. , Svanegård J. , Poulsen J.
Published: June 2015

The changes in plasma concentrations of atrial natriuretic peptide were investigated in 10 patients who were examined for peripheral vessel disease by aorto-femoral angiography. All patients received 6×40 ml contrast medium (iohexol, 300 mg I/ml) plus an initial test dose of 15 ml, resulting in a total mean dose of 255 ml injected into the abdominal aorta. The contrast medium injections produced a significant increase in plasma atrial natriuretic peptide concentration (p<0.02). Furthermore a significant decrease was seen in systolic blood pressure (p<0.04). It is concluded that the plasma concentration of atrial natriuretic peptide increases after intraarterial injection of contrast medium, and that atrial natriuretic peptide might play a role in the hemodynamic changes seen after intravascular injections of contrast medium.
Percutaneous Transluminal Laser Angioplasty
Authors: Yang X. M. , Manninen H. , Soimakallio S.
Published: June 2015

The progress in percutaneous transluminal laser angioplasty (PTLA) over the past two years is presented. The technical development includes the application of new equipments to laser sources, delivery systems and monitors. We review new experimental research in rapidly establishing animal models and human postmortem specimens, as well as efforts to select adequate wave length and irradiation time for laser energy with suitable infusion media. A summary of clinical trials is given on expanding usage, complication rates and long-term patency of PTLA. The current trends in PTLA respecting guide wire assisted balloon angioplasty and other recanalization methods are described.
Embolization of Cerebral Arteriovenous Malformations with Bucrylate
Authors: Berthelsen B. , Löfgren J. , Svendsen P.
Published: June 2015

The experience with embolization of intracerebral arteriovenous malformations (AVMs) with bucrylate (isobutyl-2-cyanoacrylate) in 29 patients is reported. In 9 cases (31%) less than 1/3 of the AVM nidus was occluded, in 12 (41%) 1/3 to 2/3, in 4 (14%) more than 2/3, and total occlusion was only seen in 3 cases (10%). One patient was never embolized, owing to procedure complications. At follow-up angiography in 20 patients, partial revascularization was found in 11 AVMs and further occlusion in 2. Complications occurred in 11 cases (38%). Five patients (17%) suffered from hemorrhage: 2 died, one deteriorated severely and 2 recovered. Unintentional embolization or edema resulted in neurologic deficits in 6 patients (21%), permanent in 3 and reversible in 3. Symptomatic improvement was initially found in 13 patients (45%) but was stable only in 9. In 9 patients (38%) embolization was followed by elective surgery or irradiation. The best results were obtained in small and medium-sized AVMs (<6 cm) while there was a high risk of complications and an uncertain palliative effect in large AVMs.
CT Morphology of Benign Median Nerve Tumors
Authors: Feyerabend T. , Schmitt R. , Lanz U. , Warmuth-Metz M.
Published: June 2015

Computed tomography (CT) was performed in 3 patients with benign tumors of the median nerve, histologically confirmed as neurilemmoma, fibrolipoma and hemangioma. The neurilemmoma showed a ring-shaped contrast enhancement. The fibrolipoma presented with areas of solid soft tissue and areas of fat. The hemangioma was a solid tumor with a lacunar, vascular contrast enhancement. According to our experience and to the previous literature CT gives useful information regarding the anatomic location, size, and relationship of peripheral nerve sheath tumors to surrounding structures, and may help to differentiate between various tumor types.
Comparison of Non-Enhanced, Bolus Enhanced, and Delayed Scanning Techniques in Computed Tomography of Hepatic Tumours
Authors: Tidebrant G. , Asztely M. , Lukes P. , Tylén U.
Published: June 2015

Non-enhanced, bolus contrast medium enhanced and 4 to 6 hours delayed computed tomography of the liver was performed in a prospective study of 53 patients. Forty patients had focal lesions, in 12 of these they were hypervascular. Contrast medium was administered as an initial bolus followed by a rapid injection of meglumine metrizoate (Isopaque Cerebral). The total iodine dose varied between 56 and 63 g, which gave an average increase in attenuation of 14 HU in normal parenchyma comparing delayed with non-enhanced scanning. Presence and extent of focal lesions were evaluated in a randomized and independent analysis by two radiologists. The percentage of examinations with correct tumour description was higher with bolus scanning (observer I 73%, observer II 75%) and delayed scanning (observer I 75%, observer II 78%) than with non-enhanced scanning (observers I and II 67%). An optimal bolus technique requires an exact timing of the contrast medium administration and scanning. Delayed scanning provides an excellent supplement when the bolus examination is suboptimal or shows equivocal findings.
Percutaneous Puncture and Drainage of Pancreatic Pseudocysts; a Retrospective Study
Authors: Aurell Y. , Forsberg L. , Hederström E. , Andersson R.
Published: June 2015

Experience with 19 consecutive patients who had 20 pancreatic pseudocysts treated by percutaneous puncture and/or drainage was reviewed. Ten pseudocysts (5 infected, 5 non-infected), underwent complete resolution after percutaneous treatment only and there was a considerable regression in 6 (5 infected, 1 non-infected), which means an overall cure rate of 80 per cent. Only one small pseudocyst remained unchanged. Complementary surgery was necessary in 3 cases. Fine needle evacuation was the method in 13 cases (11 cured) and catheter drainage in 7 (5 cured). We conclude that percutaneous drainage is a safe method for the treatment of pancreatic pseudocysts, that will cure the patient in most cases.
Phlebographic Findings in Venous Thrombosis following Total Hip Replacement
Authors: Kälebo P. , Anthmyr B.-A. , Eriksson B. I. , Zachrisson B. E.
Published: June 2015

The specific appearance of venous thrombosis following total hip replacement was analysed by reviewing 45 positive phlebograms from 122 patients participating in a concurrent trial against thromboembolism. Almost all thrombi were asymptomatic and non-occlusive. Forty-four per cent of the thrombi were excusively confined to the calf. The muscular veins were the most common location, followed by the fibular and posterior tibial veins. Ipsilateral thrombi predominated over thrombi in the non-operated leg. Thirty-six per cent were located in the ipsilateral thigh and the major part was found in the proximal part of the femoral veins. Nearly all were related to valve cusps, free-floating and were of small size. In 20 per cent, thrombi were found in both the calf and the thigh. Neither contralateral thigh thrombi, nor pelvic thrombi were found. Of 25 patients with pulmonary embolism, all but 3 asymptomatic, 64 per cent had thigh thrombi. A multifocal location of thrombi was present but two major types of thrombosis were distinguished; calf vein thrombosis probably due to venous stasis and femoral thrombosis caused by the local surgical trauma.
Prognostic Factors in Liver Metastases after Transcatheter Arterial Embolization or Arterial Infusion
Authors: Yamashita Y. , Takahashi M. , Koga Y. , Saito R. , Nanakawa S. , Hatanaka Y. , Sato N. , Nakashima K. , Urata J. , Yoshizumi K. , Ito K. , Sumi S.
Published: June 2015

From January 1986 to December 1988, 85 patients (55 men and 30 women, mean age 59 years) with metastatic liver tumors were treated with hepatic artery embolization (TAE) or infusion (HAI). Sixty-eight patients with successful catheterization were treated with TAE using iodized oil (Lipiodol) mixed with anticancer agent (ACA). In 12 of 68 patients with hypervascular tumors gelatin sponge was added. Patients with unsuccessful catheterization were treated with hepatic artery infusion of ACA. Forty-three patients received oral chemotherapy following TAE or HAI. Overall, the 6-month, and 1- and 2-year survival rates were 69.5, 31.8 and 4.1 per cent, respectively (mean 233 days). A univariate analysis of prognostic factors showed that number of metastases, stage, treatment times and oral chemotherapy were all significant factors (p<0.05). Ascites, jaundice, percentage of hepatic replacement and treatment protocol also had some influence (p<0.1). Sex, age, primary site, elevation of tumor markers, other metastatic lesions, portal vein involvement and difference in anticancer agent had no prognostic significance. A multivariate analysis using Cox's proportional hazard model revealed that the number of treatments had the most important prognostic significance, followed by oral chemotherapy, stage and percentage of hepatic replacement.
Ultrasonically Guided Percutaneous Treatment of Liver Abscesses
Authors: Juul N. , Sztuk F. J. S. , Torp-Pedersen S. , Burcharth F.
Published: June 2015

Twenty-two patients with liver abscesses demonstrated by ultrasonography (US) were treated over a nine-year period. The diagnosis was in all cases verified by puncture. The patients were treated by US-guided puncture or catheter drainage. Seventeen patients (77%) were cured without surgical drainage. Four patients were cured after subsequent surgical intervention. One patient died later of pancreatic carcinoma. There were no complications from the US-guided therapy. For the treatment of liver abscesses we recommend US-guided drainage as the first choice. Close collaboration between surgeon and radiologist is mandatory since some of these patients still need surgical treatment.
Duplex Doppler Ultrasonography for Monitoring Liver Transplants
Authors: Kubota K. , Billing H. , Ericzon B.-G. , Kelter U. , Groth C. G.
Published: June 2015

The utility of duplex Doppler ultrasonography (US) for monitoring was evaluated after 19 liver transplantations. The assessment of the resistive index (RI) of the hepatic arteries showed no significant difference in the RI measured in grafts with stable function compared with grafts with ischemic damage, acute rejection, chronic rejection, or cytomegalovirus hepatitis. Nor was there any correlation between the levels of RI and the severity of acute rejection. In 2 out of 5 liver transplants in which hepatic artery pulsations were not identified with US, hepatic artery thrombosis was found at angiography. Although high echogenicity of the parenchyma was often observed during acute rejection episodes, it was not diagnostic for rejection. Fluid collections observed around the grafts resolved spontaneously. Thus, duplex Doppler US for monitoring liver transplants is especially useful for the diagnosis of hepatic artery thrombosis. It was not helpful for the diagnosis of acute or chronic rejection.
Treatment of Hepatocellular Carcinoma by Segmental Hepatic Artery Injection of Adriamycin-In-Oil Emulsion with Overflow to Segmental Portal Veins
Authors: Nakamura H. , Hashimoto T. , Oi H. , Furui S. , Sawada S. , Mizumoto S. , Monden M.
Published: June 2015

Hepatocellular carcinoma was treated with slow injection of an emulsion containing 40 to 60 mg of adriamycin and 3.5 to 12 ml of Lipiodol into the portal vein via a segmental hepatic artery. During and after the injection, the portal branches of the segment were demonstrated. Six patients with resectable hepatocellular carcinoma received this treatment, which in 3 of them was followed by embolization with Gelfoam of the segmental artery. In these 3, all main tumors and daughter nodules became completely necrotic, but some infarction developed in the non-tumorous area. Those without Gelfoam had complete necrosis of all daughter nodules, but incomplete response of the main tumor. This combined treatment may be recommended for patients with localized lesions which are non-resectable due to cirrhosis, or for other reasons.
Diagnosis and Percutaneous Treatment of Pyogenic Hepatic Abscesses
Authors: Hochbergs P. , Forsberg L. , Hederström E. , Andersson R.
Published: June 2015

Twelve patients with intrahepatic abscesses were examined with computed tomography and ultrasonography between 1979 and 1988. The median size of the lesions was 7 (1–12) cm. They were in 8 patients located only in the right liver lobe and in 3 in both liver lobes. On ultrasonography the echogenicity of the abscesses varied from hypo- to hyperechoic which is consistent with tumours. The final diagnosis of abscess was achieved by fine needle puncture and aspiration for bacterial culture. Nine patients were treated with percutaneous drainage, 3 of them with two catheters, and all received systemic antibiotic treatment. All patients survived the treatment.
Anatomic Variations of the Cochlea and Relations to other Temporal Bone Structures
Authors: Dimopoulos P. , Muren C.
Published: June 2015

A thorough knowledge of the normal range of variation of anatomy and topography of the cochlea is necessary for optimal reproduction of this structure and correct interpretation of the radiographs. Radiographic identification of incomplete cochlear coils is essential in the diagnosis of congenital malformations such as Modini's deformity. Furthermore, a diagnosis of otosclerosis/otospongiosis has to be based on recognition of changes in the otic capsule. The size and shape of the human cochlea and the normal ranges of variation of its dimensions were evaluated in 95 plastic casts, prepared from temporal bone specimens. The normal range of variation is fairly small, and is not age-dependent. Obvious digression from this range, associated with pertinent clinical symptoms, indicates an abnormality.
Is There a Correlation between Spin-Lattice Relaxation Time and Radiation Sensitivity?
Authors: Akber S. F.
Published: June 2015

The sensitivity for cell death induced by ionizing radiation and the spin-lattice relaxation time of water protons varies with the concentration of paramagnetic molecular oxygen. These two effects are complementary.
Aberrant Right Gastric Vein Directly Communicating with Left Portal Vein System
Authors: Takayasu K. , Aoki K. , Ichikawa T. , Ohmura T. , Sekiguchi R. , Terauchi T. , Takayama T.
Published: June 2015

In 3 patients with primary hepatic malignancies, a communication between the right gastric vein and the left portal vein system was recognized at angiography. The right gastric vein entered directly into the left lateral portal veins in 2 patients and into the left medial portal veins in one. Portal angio-CT performed in one patient demonstrated a specific defect only in the left lateral superior area of the liver, consistent with the segmental opacification of the portal vein branch recognized on the angiogram. This rare communication was seen in 3 (1.5%) of 200 consecutive patients who underwent celiac angiography and is most likely an anomaly in which the right gastric vein directly enters the left portal vein instead of the portal vein trunk. When interpreting a filling defect not associated with a mass lesion on portal angio-CT for hepatic neoplasms or the right gastric vein communicating with the left portal vein system on the angiogram, this particular anomaly should be considered.
Ultrasound Guidance for Pericardiocentesis
Authors: Taavitsainen M. , Bondestam S. , Mankinen P. , Pitkäranta P. , Tierala E.
Published: June 2015

Sonographic guidance with 41 punctures and 38 catheterizations was employed in 68 patients. The approach was either intercostal or subxiphoid. Most punctures were performed with a 1.4-mm-thick plastic-sheathed cannula after local anesthesia. Complications were observed in 7 patients. In one patient a catheter introduced with a movable core-type guidewire pierced the right ventricle wall with uneventful recovery after surgery. Intercostal drainage caused pleural pain in 2 patients, and in 2, leakage to the pleural space. Two patients with heart transplants had severe bradycardia and drop of blood pressure, one after needle drainage and the other during guidewire manipulation. Direct monitoring generally ensures a correct position of the instruments and hazards to adjacent organs can be avoided. In small effusions a simple needle aspiration with a plastic-sheathed cannula is safer than catheter drainage.
Differential Diagnosis of Gastric Adenoma and Type IIA Early Gastric Cancer
Authors: Tsuchigame T. , Ogata Y. , Sumi M. , Fukui K. , Saito R. , Nakashima K. , Urata J. , Arakawa A. , Saito Y. , Takahashi M.
Published: June 2015

The endoscopic and radiographic findings of 45 gastric adenomas in 39 patients were followed for 6 months to 13 years and compared with type IIa early gastric cancer observed in 9 patients. Difficulties in the differential diagnosis of these disorders were evaluated. The following features were suggestive of gastric adenomas: clustered lesions; protuberance with gentle slope; smooth surface; and relatively young patients. Discrimination of adenoma from type IIa early gastric cancer is often difficult by visual observation alone; biopsy was essential in most patients. A group III adenoma verified on biopsy should be followed closely because the lesion may harbor a cancer (so-called carcinoma-in-adenoma) or a cancer may later develop.
Life-Threatening Post-Nephrolithotomy Hemorrhage Resulting in Cessation of Kidney Function, Treated by Transcatheter Arterial Embolization with Subsequent Restoration of Excretory Function
Authors: Szmigielski W. , Hanna R. M. , Dahniya M. H. , Hatab M. T. , Reddy C. K.
Published: June 2015

A massive post-nephrolithotomy renal hemorrhage was successfully controlled by selective arterial embolization using Gelfoam particles. Prior to embolization, the kidney showed no excretory function due to complete obstruction of its collecting system by blood clots. Long-term observation revealed restoration of excretory function of the treated kidney and only minimal loss of its parenchyma.
Cutaneous Seeding of Renal Carcinoma by Chiba Needle Aspiration Biopsy
Authors: Shenoy P. D. , Lakhkar B. N. , Ghosh M. K. , Patil U. D.
Published: June 2015

Fine needle aspiration biopsy yields a high rate of positive tissue with negligible local sequelae. We report the first instance known to us of Chiba needle tract seeding following this biopsy technique in a patient with renal malignancy.
Features of Irradiated Urinary Bladder Tumors and Their Correlation with Malignancy Observed on Computed Tomography
Authors: Sager E. M. , Kaalhus O.
Published: June 2015

CT features of 42 masses in the bladder wall were characterized and subjected to analysis to find indicators of malignancy. A CT technique with thin slices and intravenous contrast medium was used. Multiple regression and multivariate analysis showed good ability of contrast-enhanced CT to discriminate between benign and malignant masses in the bladder wall. Protrusion of a mass into the perivesical fat had some importance in discriminating between malignant tumors with and without perivesical growth although the detection of perivesical growth was less certain.
Digital Luminescence Mammography
Authors: Jarlman O. , Samuelsson L. , Braw M.
Published: June 2015

In a pilot study, mammography using digital luminescence was compared to conventional film-screen mammography regarding detectability of micro-calcifications and malignant tumors. The data processing algorithms were designed by the manufacturer to produce an image with characteristics close to conventional mammograms. Three observers reviewed 99 digital and their corresponding conventional mammograms. There was no difference in the detectability of micro-calcifications between digital and conventional mammography. On the digital mammograms, however, artifacts were misjudged as micro-calcifications. In an ROC analysis regarding malignant breast tumors, no significant difference was found between the 2 systems. There was a slight, but not significant, difference between the results of different observers regarding the digital system.
Air in Vagina
Authors: Hadar H. , Kornreich L. , Heifetz M. , Herskovitz P. , Horev G.
Published: June 2015

Computed tomography of the normal female pelvis may show the presence of a tiny air bubble within the vagina. Among 2800 female abdomino-pelvic CTs, 27 were found to contain large amounts of intravaginal air. Twenty-three patients suffered from pelvic malignancy while in 4, non-tumorous pelvic pathology was present. Detection of air bubbles in the vagina is abnormal and indicates, in the majority of cases, an intrapelvic malignancy.
Ultrasonography of Breast Lesions Detected in Mammography Screening
Authors: Pamilo M. , Soiva M. , Anttinen I. , Roiha M. , Suramo I.
Published: June 2015

Mammography screening was carried out in 18012 women (aged 50–59) of whom 579 (3.21%) had to be recalled for clinical mammography. After completion of the clinical mammography each woman also had ultrasonography (US) with a hand-held real-time apparatus using a 7.5 MHz probe. There were 79 verified breast cancers; 32 of these were palpable and were also depicted at US, but only 29 (61.7%) of non-palpable breast cancers (n = 47) were found at US. Twenty-two of the non-palpable breast cancers were seen at US as a tumor-like lesion, 2 because of local echo-architecture distortion, and 5 only because of acoustic shadowing. The US image did not help to differentiate between malignant and benign lesions.
MR Imaging of Spinal Neurofibromatosis
Authors: Li M. H. , Holtås S.
Published: June 2015

The MR findings in 7 patients with neurofibromatosis involving the spine were evaluated. Six patients had paraspinal tumors at multiple levels. In 4 they were bilateral. Five patients had multiple intraspinal lesions, frequently with growth through the neural foramen. In one patient paraspinal tumors were found in the lumbar sacral plexus and in another bony dysplasia and meningoceles but no tumors were disclosed. In 2 patients the lesions were associated with bilateral acoustic neuromas and multiple intracranial meningeomas. In one of these a spinal meningeoma with signal characteristics close to spinal cord was found. The other tumors had a signal that was equal to or slightly lower than the spinal cord and slightly higher than muscle on T1-weighted images. On T2-weighted images the tumors had a markedly increased signal compared to surrounding tissue. In 3 patients with tumors larger than 4 cm the signal intensity was inhomogeneous with decreased signal in the center on T2-weighted images, indicating the presence of increased fibrous tissue. Gadolinium-DTPA was given to one patient with marked increase in intensity of small tumors on T1-weighted images. The study shows that MR imaging is the modality of choice for evaluating most aspects of spinal and paraspinal neurofibromatosis.
Short Pancreas in Polysplenia Syndrome
Authors: Hadar H. , Gadoth N. , Herskovitz P. , Heifetz M.
Published: June 2015

Two cases with the polysplenia syndrome also had a short pancreas. To the best of our knowledge the radiologic characteristics of this anatomic anomaly have not yet been reported. Both cases were asymptomatic with regard to their anomaly-complex. The radiologic findings of the short “pancreas” are similar to the only pathologic description of this association. The awareness of this association led to the diagnosis of the second case after a few months only. A physician performing ERCP in the polysplenia syndrome should keep in mind the possible presence of the “short pancreas” when the whole length of the pancreatic duct is not visualized.
Paroxysmal Nocturnal Hemoglobinuria
Authors: Kim S. H. , Han M. C. , Lee J. S. , Kim S.
Published: June 2015

A case of paroxysmal nocturnal hemoglobinuria (PNH) is presented in which MR imaging and CT findings were characteristic. The signal intensity of renal cortex was lower than that of medulla on both T1- and T2-weighted imaging. On CT without contrast enhancement the attenuation of renal cortex was higher than that of renal medulla. These findings at MR imaging and CT were the results of a deposition of hemosiderin in the cells of proximal convoluted tubules, and were helpful for diagnosis of PNH.
Characteristic Fat-Fluid Level at Ultrasonography of Ovarian Dermoid Cyst
Authors: Øwre A. , Pedersen J. F.
Published: June 2015

An uncommon sonographic pattern was observed in 2 dermoid cysts. An echogenic upper and an echo-free dependent component were separated by a horizontal delineation, an observation that could be reproduced in a laboratory model. We believe that this finding is pathognomonic for a dermoid cyst.
Absence of Functional Renal Effects of Uro-Angiographic Contrast Media on Post-Ischemic Rat Kidneys
Authors: Verbaeys A. , Van Maele G. , De Sy W. , Ringoir S. , Lameire N.
Published: June 2015

Water soluble ionic contrast media (CM) and glucose 5% were administered to Sprague-Dawley rats 36 hours after bilateral warm renal ischemia for 45 min. In all animals (n = 28) the renal ischemia caused a decrease of the absolute urinary creatinine output. Intra-arterial injection of glucose 5% or CM did not produce different patterns of absolute urinary creatinine output. The serum creatinine increased after 36 hours of reflow. When compared by means of a Mann-Whitney U-test to a normal median serum creatinine obtained in a separate group of 22 normal rats, the increase was statistically significant (p≤0.01). The serum creatinine medians returned to a normal level after 24 hours. It seems therefore that 45 min of warm renal ischemia and 36 hours of reflow is an insufficient challenge to the rat kidney for the detection of the nephrotoxic properties of CM as opposed to when CM are injected during ischemia.
Percutaneous Embolization of Ruptured Splanchnic Artery Pseudoaneurysms
Authors: Okazaki M. , Higashihara H. , Ono H. , Koganemaru F. , Hoashi T. , Inada S. , Kuroda Y.
Published: June 2015

The usefulness of emergent embolotherapy was evaluated in 17 patients with life-threatening hemorrhage from 18 ruptured splanchnic artery pseudoaneurysms. Complete hemostasis was obtained in 16 out of 17 patients by embolotherapy. Of the 12 initial embolization procedures with permanent embolic materials including stainless steel coils, microcoils, and Ivalon, complete cessation of bleeding was obtained in 11. On the other hand, 6 out of 9 initial embolization procedures with Gelfoam particles failed to halt bleeding, and additional embolization with permanent embolic materials was required. Emergent embolization with permanent embolic materials using superselective catheterization should be considered the initial treatment of choice for ruptured splanchnic artery pseudoaneurysms.
Scintigraphy with 99mTc-HMPAO Labeled Leukocytes in Acute Cholecystitis
Authors: Lantto E. , Järvi K. , Laitinen R. , Lantto T. , Taavitsainen M. , Talvitie I. , Vorne M.
Published: June 2015

99mTc-HMPAO labeled leukocyte scanning was performed on 38 patients with clinically suspected acute cholecystitis (AC) to evaluate its diagnostic value. The typical finding was an increasing accumulation of the tracer in the gallbladder wall in a 4 hour series of scintigrams. Leukocyte scan was positive in 16 of 17 patients with surgically and histologically confirmed AC. There were no false-positive findings. The sensitivity, specificity, and accuracy of scintigraphy were 94, 100, and 96%, respectively. In 2 patients with acute acalculous cholecystitis true-positive findings were observed. Scintigraphy with 99mTc-HMPAO labeled leukocytes is a valuable new imaging method in AC.
Aortography Delays Surgery of CT Proven Acute Traumatic Rupture of the Thoracic Aorta
Authors: Muñoz A. , Moreno R. , Martín V. , Iñiguez A. , Alvarez J.
Published: June 2015

A case of acute traumatic rupture of the thoracic aorta was diagnosed by dynamic CT. Angiographic confirmation was required, delaying surgical repair and contributing to the fatal outcome. If reliable findings of acute traumatic rupture of the thoracic aorta are shown by CT, we question the usefulness of angiographic confirmation in such cases.
CT Findings of Endobronchial Metastasis
Authors: Ikezoe J. , Johkoh T. , Takeuchi N. , Ishida T. , Morimoto S. , Kitamura I. , Ohshima M. , Kozuka T.
Published: June 2015

One hundred and sixty-one patients with pulmonary metastases were studied with CT. Six of them proved to have endobronchial (intraluminal) metastatic lesions by bronchoscopy. Retrospective analysis of the CT studies showed obstruction and/or narrowing of the bronchi in 5 cases while no lesion was observed in one patient. Although CT can not always demonstrate intraluminal lesions, it should be performed when an endobronchial metastasis from extrathoracic malignancy is seen by bronchoscopy because it will show hilar or mediastinal lymphadenopathy, or single or multiple pulmonary metastases other than the endobronchial lesion.
Decreased Perfusion in Myocardial Region of Normal Donor Artery Secondary to Collateral Development
Authors: Koga Y. , Takahashi M. , Kojima A. , Takaki Y. , Tomiguchi S. , Hirota Y. , Kugiyama K. , Yasue H. , Hayasaki K.
Published: June 2015

Thirty-one patients suffering from single vessel exertional angina with collaterals (Group A) were evaluated by stress 201T1 myocardial emission CT (T1-SPECT) with 16 controls of severely stenotic single vessel exertional angina without collaterals (Group B). Group A included 21 patients (68%) who showed an extensive perfusion defect in double artery myocardial regions, including the normal donor artery myocardial region (DMR). However, there were no such cases in Group B, giving a significant difference between these 2 groups (p < 0.001). Four patients in Group A, having a perfusion defect both in DMR and in the collateral dependent myocardial region (CMR) underwent a successful percutaneous transluminal coronary angioplasty (PTCA) with disappearance of collaterals. T1-SPECT findings after PTCA showed no perfusion defect either in CMR or in DMR. This has been explained on the basis that the coronary collaterals stole blood and produced perfusion defect in DMR.
“Chess-Board Pattern” Spatial Modulation of Magnetization
Authors: Thomsen C.
Published: June 2015

Heart motion is a complex combination of translation, rotation, and concentric contraction. Evaluation of these complex motions has been difficult using conventional slice-selective methods. Non-Invasive tagging of the heart has been obtained by the use of slice-selective radiofrequency pulses. Through spatial modulation of the magnetization the entire image can be labeled in different patterns. Two new pulse sequences are presented, giving a chess-board like spatial modulation. These pulse sequences have several advantages compared with the previously published methods, as the modulation time is half that required to obtain a 2-dimensional grid, the area in the image with high signal intensity was significantly larger, and the radiofrequency power deposition was substantially decreased. By labeling the heart at diastole the chess-board pattern tagging of the heart wall could be followed through systole. Using this method the complex motions of the heart can be mapped.
Rhabdomyosarcoma of the Petrous Ridge
Authors: Zampa V. , Mascalchi M. , Giordano G. P. , Bongini U. , Pozzo G. Dal
Published: June 2015

The CT and MR findings are reported in a case of biopsy proven rhabdomyosarcoma of the skull base. The tumor presumably originated in a pneumatized petrous ridge and had an atypical presentation of multiple cranial nerve palsy. The lesion exhibited a soft tissue density and a nonexpansile bone destruction on unenhanced CT. On MR imaging the lesion showed homogeneous intermediate signal intensity on T1 weighted images and a high signal intensity on proton density and T2 weighted images. The scanty literature on CT and MR features of rhabdomyosarcoma of the head and neck is reviewed.
Radiography of the Male Breast in Gynecomastia
Authors: Rissanen T. J. , Mäkäräinen H. P. , Kallioinen M. J. , Kiviniemi H. O. , Salmela P. I.
Published: June 2015

In order to investigate the role of imaging methods in the evaluation of the male breast we reviewed the mammograms and ultrasonograms (US) performed in 40 men with breast enlargement or pain. The patients, whose breasts were examined by either mammography (n = 7) or US (n = 1) or both (n = 32), ranged in age from 14 to 83 years. The final diagnoses were gynecomastia in 35 patients, lipomas in one, abscess or sequelae to abscess in 2, and normal in 2. In gynecomastia the subareolar density was of varying shape and size or showed a diffuse pattern of heterogeneous density occupying the whole breast on mammography, and a retromammillar hypoechoic focus, a diffuse heterogeneous area, or a combination of these was observed at US. Eleven breasts and one axillary lymph node were examined by US-guided fine-needle aspiration biopsy (FNAB), which was diagnostic in all cases. Mammography is recommended for the evaluation of the male breast if the differential diagnosis between gynecomastia and fatty enlargement is not clinically evident, and in all cases of unilateral breast symptoms. US is a complementary method to mammography and is also useful to provide guidance for FNAB.
CT-Guided Percutaneous Drainage and Fluid Aspiration in Intensive Care Patients
Authors: Schurawitzki H. , Karnel F. , Stiglbauer R. , Schimmerl S. , Salomonowitz E.
Published: June 2015

Fifty-two intensive care unit (ICU) patients with clinical signs of sepsis who were considered to be at extremely high risk for operation were subjected to CT-guided interventions. Bedside ultrasound (US) had been performed prior to CT in all patients but diagnoses were equivocal or US-guided interventions had failed. Nineteen patients solely underwent CT-guided diagnostic aspiration of fluid collections to rule out infection. Eighteen patients (72%) with abscess formations after surgery or trauma were cured by catheter drainage alone; 4 patients required additional surgery. Out of 8 patients suffering from acute pancreatitis (after several necrosectomies), abscesses could be cured in 5 (62.5%). Three patients with acute necrotizing pancreatitis (no surgery) were not cured by the interventional procedure and all required surgical debridement. Even patients who required additional surgery after drainage improved clinically after the interventional radiologic procedure. Our overall success rate was 64%, emphasizing the need for CT in the case of equivocal US results or if US-guided procedures have failed in ICU patients with signs of sepsis.
Carotid-Cavernous Fistula Treated with Detachable Balloon during Bilateral Transcranial Doppler Monitoring of Middle Cerebral Arteries
Authors: Nakstad P. H. , Hald J. K. , Sorteberg W.
Published: June 2015

A traumatic carotid-cavernous fistula was closed with a silicone detachable balloon. Prior to the closure of the fistula, clinical and transcranial Doppler testing was performed in order to evaluate the consequences of a possible occlusion of the carotid artery. A newly developed Doppler technique with bilateral simultaneous velocity recordings of the middle cerebral arteries was useful during the procedure. The detachable balloon was effective in closing the fistula, but collapse of the balloon and the development of an extradural aneurysm was found at control examinations.
Leukotriene B4and Peptido-Leukotriene Levels during Radiographic Contrast Media Infusion
Authors: Gardinali M. , Pozzato C. , Conciato L. , Di Bello M. , Calcagno A. , Uslenghi C. , Agostoni A.
Published: June 2015

The pathogenic mechanisms of radiographic contrast media (CM) reactions are still not well understood. Recently it has been proposed that leukotrienes (LT) may be involved in CM reactions. We measured plasma LTB4and peptido-LT levels in 20 subjects undergoing urography with 2 low osmolality CM (ioxaglate and iopamidol) in order to elucidate if CM infusion determines LT release in plasma. LTB4and peptido-LT did not change significantly during infusion of the 2 CM. Blood pressure, heart rate, and the number of circulating granulocytes were not affected by CM infusions, further evidence that LT release did not occur. We conclude therefore that LT are not released during infusion with the CM studied.
Granulocyte Chemotaxis before and after Urography
Authors: Rasmussen F. , Georgsen J. , Pedersen J. O. , Antonsen S.
Published: June 2015

Granulocytes isolated from whole blood of 10 volunteers with Hypaque/Ficoll or Percoll gradient centrifugation showed a significant inhibition of their chemotactic response when incubated with diatrizoate. The influence of 4 different i.v. injected radiographic contrast media (CM) on granulocyte chemotaxis was evaluated using the under agarose assay. Each CM was injected in 10 consecutive outpatients referred for urography. Cells and serum were obtained before and 20 min after the injection of CM. Autologous serum was used as chemoattractive agent, and the cell suspensions from both samples were tested against serum drawn both before and after the injection of CM. No significant changes in granulocyte chemotaxis or the chemotactic potential of serum were seen. Furthermore, there was no change in the chemotactic response towards homologous serum or N-fmlp after injection of diatrizoate or iohexol. In conclusion, the investigation did not unveil any change in granulocyte chemotaxis 20 min after the injection of CM in the 40 subjects studied.
Mr Imaging of Chronic Alcoholism
Authors: Hayakawa K. , Kumagai H. , Suzuki Y. , Furusawa N. , Haga T. , Hoshi T. , Fujiwara Y. , Yamaguchi K.
Published: June 2015

We evaluated the brain lesions of patients with chronic alcoholism (n = 34) in comparison with age- and sex-matched controls (n = 40) by MR imaging. T1-weighted sagittal and axial images and T2-weighted axial images were obtained with a 0.5 T superconducting MR unit. Various brain measurements were then performed, and the presence of regions of abnormal signal intensity was also compared between the two groups. The brain measurements revealed significant cerebral atrophy (characterized by lateral and 3rd ventricular dilatation, and widening of the interhemispheric fissure) as well as significant cerebellar atrophy (represented by 4th ventricular dilatation) in the alcoholic group. These changes were more prominent in patients in their fifties and sixties than in those aged in the thirties and forties. Focal hypointense lesions were observed in 20.6% of the alcoholics and in 5% of the controls (p < 0.01), while focal hyperintense lesions were observed in 61.8% of the alcoholics and in 20% of the controls (p < 0.001). The severity of these MR findings correlated well with the age of the patients. These observations suggest that alcohol is an important promotor of brain aging.
Differential Diagnosis of Adrenal Masses Using Out-of-Phase Flash Imaging
Authors: Tsushima Y. , Ishizaka H. , Kato T. , Matsumoto M.
Published: June 2015

The purpose of this report was to suggest the ability to differentiate adrenal masses by out-of-phase FLASH imaging. The images were obtained with breath-holding at TR/TE 100/12 ms, flip angle 20°. The material included adrenal adenoma (n = 16), nodular hyperplasia (n = 1), pheochromocytoma (n = 5), and adrenal metastatic tumors (n = 7). The signal intensity ratios of the adrenal mass/the diaphragmatic crus, back muscle, and renal cortex were obtained. The mean values of the ratios of adenomas or nodular hyperplasia were significantly different from pheochromocytomas or metastases. Although the number of adrenal masses was fairly small, the ratios of adrenal mass/diaphragmatic crus could distinguish them with no overlapping case. All 17 masses with the ratio of 1.16 or less were adenomas or nodular hyperplasia, whereas all 12 masses with a ratio greater than 1.23 were pheochromocytomas or metastases. This result suggests the ability of out-of-phase FLASH imaging to differentiate adrenal masses.
Lack of Correlation between Ulnar Variance and Carpal Bone Angles on Lateral Radiographs in Normal Wrists
Authors: Larsen C. Falck , Lindequist S. , Bellstrøm T.
Published: June 2015

It has been proposed that negative ulnar variance is a predisposing factor to development of posttraumatic carpal ligamentous instability. However, this implies that no correlation exists between ulnar variance and carpal bone angles in the normal wrist. Carpal bone angles on lateral wrist radiographs and ulnar variance were measured in a series of 75 normal wrists. The mean ulnar variance was −0.03 mm (SD 1.56, range −5 to 5). The correlation coefficients were 0.06, −0.11, and −0.05 between the ulnar variance, and radiolunate, radioscaphoid, and scapholunate angles, respectively. A correlation between the carpal angles on lateral wrist radiographs, and ulnar variance in normal wrists could not be demonstrated, suggesting that the presence of negative ulnar variance may serve as an impartial clue to the presence of ligamentous instability.
Ductus Arteriosus Aneurysm Imaging Using Modern Diagnostic Methods
Authors: Laurin S. , Sandström S. , Ivancev K. , Williams J. , Lundström N.-R. , Eriksson B.
Published: June 2015

An aneurysm of the ductus arteriosus carries a high risk of rupture. The radiologic findings are described, based on a review of the literature, and on our experience of 5 patients, successfully diagnosed and treated. A left-sided mediastinal mass is always present, obscured only if the aneurysm has already ruptured. Although the lesion seems to be congenital, conventional radiology sometimes demonstrates wall calcifications. Ultrasonography is well suited to demonstrate the vascular nature of the mass, but interpretation may be difficult because of intervening air-containing lung parenchyma. CT, especially using dynamic scanning with contrast enhancement, is an excellent non-invasive diagnostic method. Angiography is frequently necessary to demonstrate patency or occlusion of the aortic and pulmonary ends of the ductus. The differential diagnosis must include a large number of mediastinal tumors. A temporary widening of the ductus in the newborn is common and must be differentiated from a true aneurysm. Surgical treatment today is usually successful.
CT Showing Early Ventricular Dilatation after Subarachnoidal Hemorrhage
Authors: Johansson I. , Bolander H. G. , Kourtopoulos H.
Published: June 2015

We performed a retrospective analysis of 398 patients with subarachnoidal hemorrhage (SAH) confirmed by CT. On the first CT examination the temporal horns were enlarged in 84%, the frontal horns in 32%, and the third ventricle in 21% of the patients. The amount of blood in the basal cisterns was highly correlated to dilatation of the temporal horns. The temporal horns were enlarged even when small amounts of blood were found in the cisterns. The frontal and temporal horns were dilated only when moderate or large amounts of blood were present in the cisterns. In 24 patients no blood was seen in the basal cisterns on CT performed within 5 days of the hemorrhage; none of the 3 patients with aneurysms showed normal temporal horns while 18 without demonstrable aneurysms had normal, and 3 had moderately dilated, temporal horns. Because the temporal horns cannot usually be seen at CT of healthy individuals, dilatation could be a useful sign in the diagnosis of SAH.
Mr Imaging of Spinal Lymphoma
Authors: Li M. H. , Holtås S. , Larsson E.-M.
Published: June 2015

Fourteen patients with spinal lymphoma examined by MR imaging were reviewed. Thirteen of them also had extraspinal lymphoma. Vertebral involvement was found in 12 patients, epidural in 10, and paraspinal in 8 patients. On the basis of MR imaging at 0.3 T, spinal lymphoma may be divided into three types of growth pattern according to the main location: paraspinal, vertebral, and epidural. Most frequently, all three locations were found simultaneously on MR (7/14). In one patient the location was vertebral with epidural extension, in one paraspinal with vertebral extension, in 3 it was entirely vertebral, and in 2 entirely epidural. Multiple plane T1-weighted imaging gave complete information about the extent of spinal lymphoma. The signal intensity was lower than or equal to muscle and lower than bone marrow in paraspinal and vertebral lesions on T1-weighted images and high on T2-weighted images. Epidural lesions showed a hypo- or isointense signal relative to the cord on T1-weighted images except in one case and a hyperintense signal on T2-weighted images. Compression of the cord and cauda equina due to bulging of diseased vertebral bodies and epidural lesions was well demonstrated. MR imaging was also found useful in the follow-up of treatment.
Assessment of Liver Iron Overload in Thalassemic Patients by Mr Imaging
Authors: Villari N. , Caramella D. , Lippi A. , Guazzelli C.
Published: June 2015

The use of MR imaging has been proposed for the assessment of the hepatic iron overload in transfusion-dependent thalassemic patients treated with desferrioxamine. The aim of the study was to correlate serum ferritine levels and MR signal intensity of the liver parenchyma. Results on 12 patients showed that the ratios between the signal intensity of liver parenchyma and muscle and fat are promising parameters for predicting iron overload.
CT Demonstration of Fat Density in Renal Cell Carcinoma
Authors: Radin D. R. , Chandrasoma P.
Published: June 2015

The presence of fat in a renal mass is almost pathognomonic of angiomyolipoma. We report a rare instance of CT demonstration of foci of fat density in a renal cell carcinoma.