bluuebunny/crossref_metadata_2025 huggingface dataset:
Higher order genes interaction in DNA repair and cytokine genes polymorphism and risk to lung cancer in North Indians
Authors: Ritambhara  , Kumar Rishabh , Gupta Maneesh Kumar , Gautam Priyanka , Tiwari Sonia , Vijayraghavalu Sivakumar , Shukla Girish C. , Kumar Munish
Published: October 2021

Context:

Lung cancer pathological process involves cumulative effects exerted by gene polymorphism(s), epigenetic modifications, and alterations in DNA repair machinery. Further, DNA damage due to oxidative stress, chronic inflammation, and the interplay between genetic and environmental factors is also an etiologic milieu of this malignant disease.

Aims:

The present study aims to assess the prognostic value of DNA repair, cytokines, and GST gene polymorphism in lung cancer patients who had not received any neoadjuvant therapy.

Materials and Methods:

In this case–control study, 127 cases and 120 controls were enrolled. DNA from the blood samples of both patients and controls was used to genotype XRCC1Arg399Gln, XPDLys751Gln, and interleukin-1 (IL-1β) genes by polymerase chain reaction (PCR)-restriction fragment length polymorphism method, whereas multiplex PCR was performed to genotype GSTT1 and GSTM1.

Results:

Binary logistic regression analysis showed that XRCC1Arg399Gln-mutant genotype (Gln/Gln, odds ratio [OR] = 4.6, 95% confidence interval [CI]: 2.2–9.6) and GSTT1 null (OR = 2.7, 95% CI: 1.6–4.5) were linked to cancer susceptibility. Generalized multidimensional reduction analysis of higher order gene–gene interaction using cross-validation testing (CVT) accuracy showed that GSTT1 (CVT 0.62, P = 0.001), XPD751 and IL-1β (CVT 0.6, P = 0.001), and XRCC1399, XPD751, and interleukin-1 receptor antagonists (IL-1RN) (CVT 0.98, P = 0.001) were single-, two-, and three-factor best model predicted, respectively, for lung cancer risk. Classification and regression tree analysis results showed that terminal nodes which contain XRCC1399-mutant genotype (AA) had increased the risk to lung cancer.

Conclusion:

The present study demonstrated that XRCC1399 (Gln/Gln), GSTT1, and IL-1RN allele I, I/II served as the risk genotypes. These genes could serve as the biomarkers to predict lung cancer risk.
A Comparative Study between Swedish Interactive Thresholding Algorithm Faster and Swedish Interactive Thresholding Algorithm Standard in Glaucoma Patients
Authors: Mendieta Núria , Suárez Joel , Blasco Cristina , Muñiz Romina , Pueyo Carmen
Published: October 2021

Purpose:

To compare the results of the new strategy Swedish Interactive Thresholding Algorithm (SITA) Faster to the results of SITA Standard in patients with glaucoma.

Methods:

This was a cross-sectional study of 49 patients with glaucoma and previous experience with standard automated perimetry. Two consecutive tests were performed in random order, one with SITA Standard and another one with SITA Faster, in the studied eye of each patient. Comparisons were made for test time, mean deviation (MD), visual field index (VFI), and number of depressed points in pattern deviation map and total deviation map for every level of significance.

Results:

The average test time was 56% shorter with SITA Faster (P < 0.001). The intraclass correlation coefficient (ICC) for MD and VFI showed excellent agreement between both strategies, ICC = 0.98 (95% confidence interval [CI]: 0.96, 0.99) and ICC = 0.97 (95% CI: 0.95, 0.99), respectively. For the number of depressed points in total deviation map and pattern deviation map, ICC demonstrated good agreement with values between 0.8 and 0.95.

Conclusions:

Our study shows that SITA Faster is a shorter test with strong agreement with SITA Standard parameters. These results suggest that SITA Faster could replace SITA Standard for glaucoma diagnosis.
Pericardium Patch Graft for Severe Corneal Wound Burn
Authors: Ashena Zahra , Holmes Christopher , Nanavaty Mayank Ambarish
Published: October 2021

Purpose:

To report a novel management technique using pericardial patch graft for severe corneal wound burn following phacoemulsification of dense cataract with shallow anterior chamber (AC) and overfilled AC with viscoelastic.

Methods:

Case report.

Results:

A 46-year-old patient with a shallow AC and dense cataract, who underwent phacoemulsification using “soft shell” technique had severe wound burn which was refractory to conventional management with corneal suturing and placing bandage contact lens. He underwent Tutoplast® (Innovative Ophthalmic Products, Inc., Costa Mesa, CA, USA) pericardium patch graft, which fully resorbed and resolved the wound leak over 6 weeks, leaving a well-healed corneal wound.

Conclusion:

Pericardium patch graft is a safe and effective technique to manage extensive phaco wound burn which is refractory to conventional management options.
Toxic Posterior Segment Syndrome Presenting as Occlusive Retinal Vasculitis Following Vitreoretinal Surgery
Authors: Sahoo Niroj Kumar , Behera Shashwat , Narayanan Raja , Chhablani Jay
Published: October 2021

Purpose:

To report a rare retinal manifestation of toxic posterior segment syndrome following vitreoretinal surgery.

Methods:

In this case series, we report three cases of rhegmatogenous retinal detachment for which pars plana vitrectomy with silicone oil injection was done. All three patients developed an intense anterior chamber reaction along with occlusive vasculitis-like fundus picture.

Results:

The three patients were started on topical and systemic steroids, and there was a dramatic improvement in vision and clinical signs at postoperative week 1.

Conclusion:

Toxic posterior segment syndrome is a sight-threatening complication after vitreoretinal surgery, but responds well to topical and systemic steroids.
The Correlation between Hypertropia and Head Tilt in Congenital Unilateral Superior Oblique Muscle Palsy
Authors: Akbari Mohamad Reza , Khorrami-Nejad Masoud , Kangari Haleh , Baghban Alireza Akbarzadeh , Raeesdana Kiana , Ranjbar-Pazooki Mahsa
Published: October 2021

Purpose:

To evaluate the correlation between the angle of deviation in different gazes and the amount of head tilt in patients with congenital unilateral superior oblique muscle palsy (SOP).

Methods:

This case series study was performed on 20 consecutive SOP patients with head tilt. Based on the Bielschowsky three-step test, the angle of deviation was measured in different gazes. Furthermore, the hypertropia difference between the two lateral gazes (gaze difference) and the two head tilt sides (bilateral head tilt difference) was calculated. For measuring head tilt, close-up pictures from 40 cm with a habitual abnormal head position were captured and analyzed by the Corel Draw X7 software.

Results:

The mean age of patients was 13 ± 9 years (range, 2.5–31 years). The mean angle of hypertropia in ipsilateral and contralateral head tilt was 24.5 Δ ± 7.1 Δ and 6.5 Δ ± 4.2 Δ, respectively (P < 0.001), and in ipsilateral and contralateral lateral gaze positions, it was 8.2 Δ ± 5.5 Δ and 22.5 Δ ± 6.1 Δ, respectively (P < 0.001). The mean of bilateral head tilt hypertropia difference was 18 Δ ± 5.3 Δ and gaze hypertropia difference was 14.3 Δ ± 6.16 Δ. There was a positive correlation between bilateral head tilt hypertropia difference and the amount of head tilt (R = 0.609, R
2 = 0.371, P = 0.004, the amount of head tilt = 0.39 × [Bilateral head tilt hypertropia difference] +1.77). The amount of head tilt also had a positive correlation with the gaze hypertropia difference (R = 0.492, R
2 = 0.242, P = 0.028, the amount of head tilt = 0.27 × [gaze hypertropia difference] +4.81).

Conclusion:

In SOP patients, the amount of head tilt had a positive correlation with bilateral head tilt hypertropia difference and also gaze hypertropia difference.
The effect of peer support in diabetes self-management education on glycemic control in patients with type 2 diabetes: a systematic review and meta-analysis
Authors: Azmiardi Akhmad , Murti Bhisma , Febrinasari Ratih Puspita , Tamtomo Didik Gunawan
Published: October 2021

OBJECTIVES: Diabetes self-management education (DSME) programs are a strategy to maintain healthy behaviors. Nevertheless, limited evidence has been reported from systematic evaluations of the effects of DSME integrated with peer support on glycemic control. This study aimed to review the effectiveness of DSME interventions integrated with peer support on glycemic control in patients with type 2 diabetes.METHODS: A systematic search was carried out in electronic databases, including PubMed, Cochrane Library, ProQuest, SpringerLink, ScienceDirect, Scopus, and Google Scholar, for English-language articles published from 2005 until 2020. The effect size was estimated as the standard mean difference (SMD). The Cochrane Collaboration’s Risk of Bias tool was employed to assess the risk of bias.RESULTS: Twelve studies were included in this study. DSME integrated with peer support effectively reduced glycated hemoglobin A1c (HbA1c) levels, with a statistically significant effect (SMD, -0.41; 95% confidence interval [CI], -0.69 to -0.13; p<0.001). Programs with a sample size <100 (SMD, -0.45; 95% CI, -0.79 to -0.11; p=0.009), duration of intervention ≤6 months (SMD, -0.52; 95% CI, -0.96 to -0.07; p=0.020), baseline HbA1c <8.5% (SMD, -0.42; 95% CI, -0.77 to -0.07; p=0.020), delivery by group (SMD, -0.28; 95% CI, -0.51 to -0.06; p=0.010), and high frequency of contact (SMD, -0.29; 95% CI, -0.48 to -0.10; p=0.003) had statistically significant effects on reducing HbA1c levels in patients with type 2 diabetes.CONCLUSIONS: DSME integrated with peer support effectively enhances glycemic control in patients with type 2 diabetes. Programs with smaller participants groups, shorter interventions, weekly meetings, and closer group sessions improved glycemic control in patients with type 2 diabetes.
Izboljševanje zdravstvene pismenosti nosečnic z uporabo sodobnih pristopov v zdravstveni vzgoji
Authors: Prosen Mirko , Ličen Sabina
Published: October 2021

Optimalne zdravstvene izide v nosečnosti povezujemo s stopnjo zdravstvene pismenosti, ki je danes prepoznana kot ključna socialna determinanta zdravja. Namen integrativnega pregleda literature je bil preučiti, kateri sodobni pristopi (intervencije) zdravstvene vzgoje za dvig zdravstvene pismenosti nosečnic so razviti v svetu ter kakšna je vključenost strokovnjakov drugih disciplin v intervencije zdravstvene vzgoje. Pregledani so bili članki, objavljeni med letoma 2010 in 2021, iz naslednjih elektronskih podatkovnih zbirk: Cinahl in Medline (prek baze EBSCOhost), PubMed in ScienceDirect. V končno vsebinsko integrativno analizo je bilo umeščenih pet kvantitativnih raziskav. Zbrani podatki so bili analizirani z metodo tematske analize. Raziskave poročajo o vplivu zdravstvene pismenosti na prepričanja/stališča, znanje in življenjski slog med nosečnostjo, obenem pa tudi kažejo na to, da je vključevanje drugih, nezdravstvenih strokovnjakov v zdravstvenovzgojne intervencije zelo omejeno. Vidne so spremembe v pristopu sodobne zdravstvene vzgoje, a hkrati tudi to, da je ta proces prepočasen in nezadostno progresiven.
Elateia 1 in Northeastern Thessaly 8000 Years Ago
Authors: Reingruber Agathe , Toufexis Giorgos , Maniatis Yannis
Published: October 2021

Intensive and systematic surveys in the area south of Mount Olympos and west of Mount Ossa revealed not only tell settlements, but also several flat sites from different prehistoric periods. For one of the settlements, namely Elateia 1, a detailed relative chronological assessment was made with the help of statistical evaluations of pottery assemblages. In addition, short-lived bone samples confirmed and more precisely defined the exact chronological position of this 10-hectare site within the Middle Neolithic period. The present study underlines the importance of statistical evaluations of complete pottery assemblages, even those obtained through survey investigations, and their significance for a better understanding of chronological, chorological and post-depositional processes.
Dental auxiliaries in tertiary hospitals in Nigeria; oral hygiene practices and dental service utilization
Authors: Alade Grace Onyenashia , Umeizudike Kehinde Adesola , Osagbemiro Babatope Bamidele , Oyetade Modupe Temitope
Published: October 2021

Objective: This study was aimed at determining the oral self-care practices and dental service utilization among dental auxiliaries in teaching hospitals in Nigeria, and also to assess the dental utilization of their relatives.

Methods: This was a descriptive, cross-sectional multicenter study conducted among dental auxiliaries from three teaching hospitals in Nigeria, namely; University of Port Harcourt Teaching Hospital (UPTH) Port Harcourt, Rivers State, Lagos University Teaching Hospital (LUTH) Idi-araba, Lagos State and University College Hospital, (UCH) Ibadan, Oyo State Nigeria. Self-administered questionnaires were used to obtain information on participants’ sociodemography, oral hygiene practices and dental service utilization. The self-rated oral health status was used to assess their oral health behavior (frequency of brushing, regular check-up and fluoride application). Statistical analysis was done using the IBM SPSS version 20.0. Statistical significance level was considered at p ≤ 0.05.

Results: A total of 101 participants were enrolled into the study, consisting of dental nurses (16[15.8%]), dental technicians (21[20.8%]), dental technologists (46[45.5%]) and dental therapists (18[17.8%]). The mean age of the participants was 35.12 ± 8.89 years. Female: Male ratio was 2.26: 1. Most (90.1%) of the study participants rated their oral hygiene as excellent. Slightly over half (57.4%) brushed twice daily; 25% of the dental nurses, 52.4% of the dental technicians, 58.7% of the dental technologists and 88.9% of the dental therapists, this was statistically significant (p=0.002). Frequency of dental check-up for six months among the participants was low (31.7%). Only 31 (30.7%) of the participants had scaling and polishing done in the last 6 months. More of the dental nurses (93.8%) and technicians (71.4%) had invited their relatives for scaling and polishing compared to the other dental auxiliaries (p=0.0019).

Conclusion: Even though the dental therapists had better tooth brushing practices in this study, the oral hygiene practices and utilization of dental services by the dental auxiliaries were generally less than optimal. There was a disparity between the self-rated oral health status and oral health practices of the dental auxiliaries. There is need for better motivation of dental auxiliaries towards optimal oral hygiene behavior.
An overview of cases of parotid gland tumors managed in a teaching hospital, North-west, Nigeria
Authors: Omisakin Olatunde Oluleke , Zubair Ramatu Aliyu , Ogunsina Modupe Arinola , Yates Sannom
Published: October 2021

Objective: Salivary gland tumors are mostly slow growing and painless. Majorities are located in the parotid glands and are benign. Treatment of these parotid tumors may endanger the facial nerve. This study evaluated the clinical presentation and management of parotid gland tumors in Kaduna, North-west, Nigeria.

Methods: This was a retrospective study of patients that were treated for parotid gland tumors at the Maxillofacial Unit of Barau Dikko Teaching Hospital, Kaduna, North-west, Nigeria over a period of 13years (January 2008 to December, 2020). Patients’ records were analyzed for age, sex, clinical presentation, investigations, surgical management, histological diagnosis and outcome of treatment.

Results: A total of 55 patients with parotid gland tumors were seen. Age range was 12 - 75 years with a mean of 45.5 (SD± 0.7) years. The male: female ratio was found to be 1.1: 1. Pleomorphic adenoma was the commonest tumour (n=28, 50.9%). Four (7.3%) patients who had been on antiretroviral medications were seen with massive tumors. Superficial parotidectomy was the commonest surgical procedure carried out in these patients. Patients with malignancies were referred for post-surgical radiotherapy. High early recurrences were noticed in patients who were retroviral positive.

Conclusion: Pleomorphic adenoma was commonest tumors treated and superficial parotidectomy was the commonest surgical procedure performed for the treatment of parotid gland tumors. Post-operative radiotherapy as an adjunct was carried out in cases with diagnosis of malignant lesions.
Knowledge and practice of health workers to tooth avulsion in a teaching hospital in Lagos, Nigeria
Authors: Ashiwaju Modupe Oluwafunmilayo , Oremosu Omotayo Adebola , Orenuga Omolola Olubunmi , Akaji Ezi Abigail
Published: October 2021

Objective: The health care workers (HCW) may be the first contact of a tooth avulsion case. This study aimed to assess their knowledge and practice of emergency management of tooth avulsion.

Methods: The cross-sectional study was carried out among health care workers in a teaching hospital, using a self-administered questionnaires containing closed and open-ended questions, on their knowledge and practice of management of tooth avulsion. Data collected was analyzed using EPI info version 7 statistical software.

Results: A total of 362 questionnaires were administered with a response rate of 90.4%. The health care workers were 331 between the ages of 18 years to 64years. There were 200 (60.4%) females and 131(39.6%) males (ratio 3:2). Less than half (41.7%) of the respondents rated their knowledge on avulsion as fair. About half of the respondents 156 (47.1%) reported that primary tooth should be replaced into the socket. The knowledge of how to hold avulsed tooth among 217 (65.6%) of the respondents was incorrect. More than half 185 (55.9%) answered that avulsed teeth, will be stored in a dry medium. Less than half, 146 (44.1%) knew the appropriate storage media to be used. Only a third 122 (36.9%) were confident in their knowledge to replant an avulsed tooth. About a third 114 (34.4%) of HCW had encountered an avulsion case, most were dentists and nurses. More than a quarter 92 (27.7%) referred the avulsion while (16.1%) did nothing to the avulsed tooth.

Conclusion: There is a need to increase the knowledge and practice of HCW, so that immediate replantation can be practiced thereby improving the prognosis for replanted teeth.
Long-term outcome after SARS-CoV-2 infection in healthcare workers: a single centre cohort study
Authors: Martinez Aurélien Emmanuel , Banderet Florian , Labhardt Niklaus D. , Battegay Manuel
Published: October 2021

BACKGROUND: Long-term symptoms after acute COVID-19 are highly debated. Nevertheless, data on long-term symptoms of COVID-19 in healthcare workers are scarce.
METHODS: We assessed frequency and risk factors of persisting symptoms in a retrospective cohort of healthcare workers infected with SARS-CoV-2.
RESULTS: Persistent symptoms at 3 and 12 months were reported by 26.5% and 13.5% of participants, respectively. Most commonly reported symptoms were fatigue, impaired sense of taste or smell and general weakness. A history of depression or state of exhaustion, pre-existing lung disease and older age were associated with persisting symptoms.
CONCLUSION: Our study shows that a relevant proportion of healthcare workers with mild COVID-19 report persisting symptoms over 3 and 12 months. Although in the majority of cases symptoms are mild, this study highlights the need for further research into causes and therapy.
Computer Support in Statics
Authors: Tvrdá Katarína
Published: October 2021

Nowadays new subjects are implemented into education process, for the sake of the support of existing profile subjects at the technical universities. The elaboration of assigned tasks on individual subjects is demanding and time consuming and therefore a subject is created, which facilitates the solving of the assigned tasks. The subject Computer support in statics tries to show the base of working with freely available programs such as SMath studio and Excel, which allow creating own user´s algorithms based on the experience gained from this subject. While elaborating the tasks from statics and elasticity, a student utilizes the knowledge gained in the mathematics and physics courses. Followingly, the knowledge from engineering statics and elasticity theory are further utilized in subjects like concrete structures or steel and wooden structures. This paper performs a computation in software Smath studio. Students confirm their theoretical background, they can follow the computation and followingly can better understand the behaviour of the structure subjected to the load.
The factor of justice in the consolidation of urban communities
Authors: Babintsev Valentin P. , Khripkova Dianna V.
Published: October 2021

The article analyzes the role of the equity factor in the consolidation of urban communities. The consolidation of the population is considered a way to achieve its stability. Social consolidation is discussed as an ambiguous concept that characterizes the process and outcome of an agreement between different communities on the basis of the unity of values and interests and the establishment of relations of mutual trust and solidarity, in order to achieve common goals. The results of the research have shown that justice is not only the dominant value of urban residents but becomes a factor that determines many daily practices of the population. As a conclusion it has empirically confirmed that, if there are significant discrepancies regarding the understanding of social justice by the inhabitants of the city and their lack of conviction in the practical implementation of this principle, consolidation remains only an illusory opportunity. Therefore, the consistent implementation of the principle of justice and the search for social consensus among various segments of the population are strategic priorities for the development of urban communities around the world.
¿Educar o evitar el pensamiento? Un análisis sobre el lenguaje y el poder
Authors: Imaicela-Reyes Marcela Karina
Published: October 2021

From the perspective of essay, this article is an analytical, but above all hermeneutic, reading of the relationships that education has maintained with thought, language, and power. The research is based, in the first place, on a rigorous and systematic documentation, and then move on to the selection of those texts that, in the opinion of the author, have greater relevance to the subject and that, in addition, represent the nuclear approaches of Michel Foucault and Edgar Morín. The arguments of these two authors are detailed and analyzed, as arduous critics of classical pedagogy, its actors, and strategies. It is concluded that, in both authors, there is an effort to find the threads of power that sustain in the periphery, some discourses, typical of an education that questions the dominant rationality and that postulate different ways of thinking, such as: an archaeology of knowledge in the style of Foucault or the complex thought proposed by Morín.
The interests of state and civil society as a determinant of the democrative political development of Central and Eastern Europe countries
Authors: Hrebeniuk Bohdan , Hrytsun Viktoriia , Bortniak Valerii , Bortniak Kateryna , Liasota Alina
Published: October 2021

The article analyses the state and development of civil society in Central and Eastern Europe as basic determinants of its development, using integrative indices of civil society sustainability. The external and internal logic of these indices for 2019 is studied. The research uses methods of cluster analysis, linear correlation, and multiple regression analysis to model the interaction of the determinants of civil society development in the region. The results of the analysis in the Central and Eastern European region reveal interesting links not only between the status of civil society and the state, but also in the relationship of factors that reflect the analytical triangle of relationships. People's satisfaction with government is not a simple consequence of the economic situation: the relationship between social wealth and economic progress. The status of civil society also turns out to be a factor in this system of relationships, along with the quality of social relations and the existing sociopsychological characteristics of the population. The numerical values of the civil society situation and development indices obtained in this way can be used in statistical models.
Problem of lawyer protection: comparative legal analysis
Authors: Turanin Vladislav Yu. , Gridchina Alexandra Vl. , Kutina Vera P. , Umarova Amala A. , Dolgov Stanislav F.
Published: October 2021

This article is dedicated to the analysis of a preponderant institution of Civil Society in Russia such as the Bar Association, consequently, its role in the implementation of the state function of providing qualified legal assistance is examined. In addition, it ad-dresses the criminal defense mechanism of the Russian legal profession. To achieve the objective of the study, several general scientific techniques, and methods of scientific knowledge (analysis, synthesis, deduction, induction, systemic-structural, formal-logical approaches) and specific scientific methods were launched: historical-legal, formal-legal, comparative-legal, and interpretative are employed. Based on the results obtained, it can be concluded that the legal profession, being an institution of civil society, remains vul-nerable in the legal sense in its interaction with law enforcement agencies. At the same time, by illegally interfering in promotion, public officials go unpunished. There is still no criminal liability for unlawful interference in the activities of a lawyer. It therefore proposes to introduce specific amendments to the criminal legislation governing this matter of general interest.
Comparative analysis of the essence of abuse of power in international legal sciences and Ukraine
Authors: Nesterenko Anna , Maryniak Nataliia , Trush Marta , Yesimov Serhii , Bohiv Yaryna , Pervii Vita
Published: October 2021

The purpose of the research is to develop a comparative analysis of the essence of the abuse of the occupational (official) position within the framework of the science of criminal law. It is indicated that criminal liability for the abuse of the occupational (official) position in the performance of his duties has been established for certain specific offences under the Special Part of the Criminal Code of Ukraine. To achieve the stated objective and solve the stipulated tasks, general and special scientific methods were used, in particular, the structural system to analyze crime in the field of official activities and prevent it as a theoretical problem and holistic phenomenon throughout the process. The results obtained allow us to conclude that, in most countries of continental Europe there is a simplification of the qualification of the actions committed by an official in a single article, however, there is a clear link with the consequences caused in the form of pecuniary damage, which allows the prosecution to build much faster a causal component of the actions of a person within a single legal criminal corpus and pass evidence to the court.
Detection and Extraction of Electronic Information During Investigative (Search) Actions Under Ukrainian Legislation
Authors: Khablo Oksana , Pysmenniy Dmytro , Halahan Oleksandr , Nykonenko Mykhailo , Kubareva Olha
Published: October 2021

The article provides a comprehensive study of the features of detection and seizure of electronic information during investigative (search) actions under the laws of Ukraine. The methodological basis of the scientific article is the complex application of general scientific and special methods of scientific knowledge in their relationship, selected considering the purpose and objectives of the study, its object and subject. It is noted that the following information, which is contained in the form of electronic-digital mappings, can be obtained during investigative (search) actions, covert investigative (search) actions, as well as during temporary access to things and documents as a measure of criminal proceedings. It is established that the process of reviewing electronic documents in general corresponds to the generally accepted algorithm of actions: search and detection of documents; visual inspection of the external state without changing the conditions of perception; fixation; detection of handprints; detection of traces of changes in the original content; preparation for packaging; packaging. It is substantiated that the involvement of a computer technician in the investigation, search, other procedural actions, aimed at solving the problems of contextual information retrieval, detection of electronic document management programs, viewing the history of visits to Internet browsers.
Political Communications of the UK Government as an Institutional System
Authors: Ivanova Oksana Mikhailovna , Guryev Mikhail Evgenievich , Sadykova Zilya Raisovna , Mingazova Nailya Rifkatovna , Khramova Ksenia Vyacheslavovna
Published: October 2021

This study examines the problem of characterizing the political communications system in Britain as a socio-political phenomenon. In the XX-XXI centuries, the intense growth of knowledge has shaped the socio-cultural and political activity of the population. Political communication becomes a separate area from human activity. In modern conditions, political communication is a set of processes, the source of which should be power. There are many processes in species diversity. Political communications in modern conditions have acquired the status of a social institution. The article attempts to present the institutional status of the phenomenon of political communication as a structure of three main components. First, the state as a governing body, represented by three powers: legislative, executive, and judicial. Secondly, society, which acts as the recipient of the initiatives of state power, or which has a positive attitude towards state policy or, negative and opposes, or has an attitude of waiting to see what happens. At the same time, there are groups in society that tend to actively intervene in politics. The third element of the political communication system is the media.
Brasil, Inglaterra e Portugal: circulação de impressos protestantes no nordeste brasileiro
Authors: Fraga Vilas-Bôas Carvalho do Nascimento Ester
Published: October 2021

Este trabalho apresenta a ação da Sociedade Bíblica Britânica e Estrangeira/BFBS no Brasil, durante o século XIX, especialmente no Nordeste, fazendo circular impressos protestantes. O referido texto tem o apoio financeiro do CNPq e integra o Projeto de Pesquisa coordenado por essa pesquisadora, intitulado Brasil, Portugal e Inglaterra: circulação de impressos protestantes e outros impressos durante os Oitocentos. A estratégia de distribuir impressos antecedeu à organização de escolas, com a finalidade de implantar definitivamente o Protestantismo no Brasil. Como essa estratégia teve sucesso num país que, na época, possuía uma população analfabeta em sua maioria? O que poderia ser visto como um problema era, na verdade, o diferencial. Quando o colportor, vendedor ambulante de impressos protestantes, chegava num determinado local que as pessoas não sabiam ler, ele propunha a organização de um grupo e se comprometia em enviar um professor para ensiná-los, que, na verdade também era um missionário. Dessa forma, eles mapearam no Brasil o território de instalação de suas futuras igrejas e escolas. A hipótese que defendo é que a intervenção de instituições protestantes na circulação e difusão de impressos possibilitou a definitiva inserção do Protestantismo no país. Este trabalho considera os impressos protestantes que circularam no Brasil e em Portugal a partir dos Oitocentos como Bibliotecas Pedagógicas Protestantes, as quais foram utilizadas como estratégias para a construção de uma civilização cristã protestante e que tinha também o objetivo de conformar um campo pedagógico. A ação de propagandistas protestante se fez presente em várias Províncias do país, dentre elas, Pará, Bahia, Maranhão, Sergipe, Pernambuco, Alagoas, Paraíba. Até meados da década de 30 do século XX, instituições protestantes distribuíram aproximadamente dez milhões de impressos de destinação religiosa e escolar. No entanto, a publicação, edição, distribuição, circulação e práticas de leituras são áreas de investigação quase intocadas durante um século pela historiografia educacional e confessional brasileira.
Continuous On-Line Leaching To Evaluate The Effect Of Toasting On Bioaccessibility, And Pb Source Apportionment Of Alternative Breads
Authors: Beauchemin Diane
Published: October 2021

Laser-induced with the increasing popularity of alternative breads, investigating their health benefits and risks is vitally important. The bioaccessibility of potentially toxic elements in these breads could indicate a potential risk to consumers. The continuous online leaching method (COLM) involves the sequential leaching of a mini-column of food by artificial saliva, gastric juice, and intestinal fluid with real time monitoring of elements being released. Because the dissolution equilibrium is shifted to the right from continuous exposure to fresh reagent, it assesses bioaccessibility in three gastrointestinal matrices in less than 30 min and includes valuable kinetic extraction information. In this study, a gluten-free (GF) and a rye bread were analyzed for As, Cd, and Pb before and after toasting. Toasting lowered all PTE concentrations by a factor of 1.5 (As in rye bread) to 2.5 (Cd in rye bread). Most of the PTEs present were bioaccessible whether the bread was toasted or not. In the case of As, a significant portion is in the form of As(III) and As(V). COLM analysis allowed for Pb sourcing, revealing two potential sources of Pb being released separately in gastric juice from rye bread based on their significantly different 206Pb/207Pb and 208Pb/206Pb isotope ratios. Comparison with Pb ratios reported in previous literature revealed that some of the gastric-mobile Pb in rye bread came from the Pb historically added to gasoline in North America. This source completely vanished upon toasting rye bread.
Gambaran Pengetahuan Ibu Terkait Makanan Sehat Dan Gizi Bagi Bayi Usia 0-12 Bulan
Authors: Harnawati Riska Arsita
Published: October 2021

Pentingnya ibu mengetahui tentang nutrisi dan gizi yang tepat dan sehat untuk bayi dengan usia 0-12 bulan yaitu agar status gizi baik, sehingga tumbuh kembang bayi akan sesuai dengan umurnya. Penelitian ini bertujuan melihat deskripsi terkait pemahaman ibu berkaitan dengan kebutuhan makanan, nutrisi, dan gizi bagi bayi usia 0-12 bulan. Metode  penelitian yang digunakan  adalah survey deskriptif, dengan jumlah sampel yang di gunakan adalah 52 responden. Cara pengambilan sampel yaitu dengan membagi kuesioner yang dbagikan kepada ibu yang mempunyai bayi dengan usia penelitian. Hasil yang didapatkan, ibu yang memiliki pengetahuan baik sekitar 35 responden (67,3%),karakteristik responden berdasarkan umur 7 responden (100%), pendidikan 17 responden (77,2%),pekerjaan 7 responden (87,5%).
Pengawasan Mutu Air Minum Dalam Kemasan Di Cv Sumber Tirta Berkah Abadi Slawi
Authors: Rosidah Nuraedi , Daryono Daryono , Purwanti Yunika
Published: October 2021

Air Minum Dalam Kemasan (AMDK) menurut Standar Nasional Indonesia 01-3553-2015 adalah air baku yang telah diproses,dikemas,dan aman diminum mencangkup air mineral dan air demineral. Air minum dalam kemasan harus memenuhi syarat-syarat standar kualitas air. Syarat tersebut berupa standar fisik, kimia, dan mikrobiologi. Pengawasan mutu penting dilakukan dari penerimaan bahan baku air  sampai produk akhir yang siap di pasarkan. Pengawasan pada bahan baku air meliputi penampungan, water treatment, ozonisasi, pengisian dan packing. Faktor utama yang mempengaruhi dalam proses pembuatan air minum dalam kemasan yang dapat menurunkan kualitas adalah tingkat kontaminasi yang sering terjadi seperti kontaminasi udara ruang produksi,dan kontaminasi air.  Tujuan penulisan laporan praktikum tentang pengawasan mutu adalah untuk mengetahui cara mempertahankan kualitas air minum dalam kemasan agar sesuai dengan SNI 01-3553-2015. Hasil obeservasi menunjukkan uji laboratorium dan uji fisik bahan penolong yang telah dilakukan CV. Sumber Tirta Berkah Abadi, memenuhi SNI 3553 : 2015.
Pengaruh Volume Penjualan dan Biaya Operasional terhadap Laba Bersih di Pangkalan LPG 3 Kg Siti Aminah Sidoarjo Periode 2017-2019
Authors: Puspitasari Siti Rahayu Deni , Fatah Abdul
Published: October 2021

Penelitian ini adalah untuk mengetahui dan menguji pengaruh volume penjualan dan biaya operasional terhadap  laba bersih perusahaan, serta untuk  mengetahui variable yang lebih dominan mempengaruhi laba Pangkalan LPG 3Kg Siti Aminah. Penelitian ini mengunakan metode penelitian kuantitatif, dengan meng-gunakan pendekatan study kasus dan lapangan. Populasi dalam penelitian ini adalah laporan keuangan periode 2017-2019. Adapun sampel dalam penelitian ini adalah 36 sampel. Teknik analisis data menggunakan uji F, uji T, dan variabel dominan dengan menggunakan aplikasi SPSS for windows. Hasil dari pengujian hipotesis kedalam penelitian ini menunjukkan bahwa Volume Penjulan dan Biaya operasional secara simultan berpengaruh dan signifikan terhadap laba bersih, volume penjualan secara parsial berpengaruh positif dan signifikan terhadap laba bersih perusahaan, biaya operasional secara parsial berpengaruh positif dan tidak signifikan terhadap laba bersih perusahaan dan volume penjualan berpengaruh dominan terhadap Laba Bersih.
ANALISIS VOLUME PENJUALAN DAN HARGA POKOK PENJUALAN UNTUK MENGEVALUASI LABA KOTOR PERUSAHAANâ€ (STUDI KASUS PADA PT. SUPARMA, Tbk)
Authors: Khoiriah Siti , Lestari Tri , Masyhad Masyhad
Published: October 2021

Penelitianinibertujuanuntukmengetahuidanmenganalisisvolumepenjualandan harga pokokpenjualanuntukpengevaluasiankenaikanlabakotoryangdilakukanoleh pihak manajemenPT.Suparma,TbkSurabayasebagaialatukur apakahmarginyang diperolehperusahaansudahtinggiatausebaliknya.Datadalampenelitianinimenggunakan datasekunderberupalaporankeuangantahunan.ObjekpenelitianiniadalahPT.Suparma, TbkSurabaya.Metodepenelitian inimenggunakan metodepenelitiandeskriptif melalui metode kualitatif. Hasilpenelitianiniadalah labakotorpadaPT.Suparma,Tbk mengalamifluktuasi.Hal tersebutdapatdilihatdarilabakotortahun2017 sebesarRp. 315.347.420.283. Labakotor ditahun2018sebesarRp. 372.929.951.083 meningkatdibandingkantahun sebelumnya tahun2017 sebesarRp.315.347.420.283.Labakotorditahun2019perseroan tercatat sebesar374.799.210.733 mengalamikenaikanyangtidaksignifikandibandingkanpada tahun2017 ke tahun 2018.
PENGARUH AKTIVITAS, PROFITABILITAS TERHADAP PERTUMBUHAN LABA (STUDI PADA PERUSAHAAN OTOMOTIF DAN KOMPONEN YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2015-2019)
Authors: Sari Dwi Lathifah , Rosyafah Siti , Masyhad Masyhad
Published: October 2021

Perusahaan memiliki tujuan utama yaitu memperoleh dan meningkatkan laba. Laba yang diperoleh perusahaan akan digunakan untuk berbagai kepentingan, salah satunya digunakan untuk meningkatkan kesejahteraan perusahaan atas produk atau jasa yang dijual. Penelitian ini bertujuan untuk mengetahui pengaruh aktivitas, profitabilitas terhadap pertumbuhan laba pada perusahaan otomotif dan komponen yang terdaftar di Bursa Efek Indonesia. Penelitian ini menggunakan pendekatan kuantitatif dengan pengumpulan data menggunakan financial statement. Populasi penelitian ini adalah perusahaan otomotif dan komponen yang terdaftar di Bursa Efek Indonesia selama periode 2015-2019. Teknik pengambilan sampel yang digunakan adalah teknik purposive sampling. Metode analisa data yang digunakan adalah analisa regresi linier berganda dengan uji hipotesis yaitu uji F dan uji t. Hasil dari penelitian ini menunjukkan bahwa Aktivitas, Profitabilitas berpengaruh secara simultan dan parsial terhadap pertumbuhan laba. Variabel Profitabilitas berpengaruh dominan terhadap Pertumbuhan Laba.
Emevî Dönemine Ait Dînâr ve Dirhemlerden Örnekler
Authors: GÜNAY Emre
Published: October 2021

İslam öncesi Arap Yarımadası ve İslam’ın yayıldığı ilk dönemlerde İslami tarzda sikke darp edilmesi hususunda herhangi bir çalışma gerçekleştirilmemiştir. Bu dönemde, Bizans dinarları ve İran dirhemleri kullanılmaya devam edilmiştir. İslami karakterde ilk sikkelerin darbını; 661-750 yılları arasında Avrupa’dan Asya’ya kadar geniş bir coğrafyada hâkimiyet sağlayan, İslam tarihinin ilk hânedan devleti olan Emevîler gerçekleştirmiştir. İslâm dünyasının kuvvetini ve bağımsızlığı simgeleyen bu sikkelerin malzemesi, tekniği ve üzerinde yer alan düzenlemeleri değerlendirildiğinde Emevîlerin ekonomik durumu, siyasi yapısı, yönetim biçimi ve sanatsal üslubu hakkında önemli bilgilere ulaşılmaktadır. Bu bağlamda çalışma, Zeno.ru arşivinde bulunan Emevî dönemine ait on sekiz sikke örneğinin kronolojik olarak hâlifelerin saltanat tarihlerine göre incelenmesi, tanıtılması ve değerlendirilmesinin yapılmasını amaçlamaktadır.
ESTUDIO FARMACOGNÓSTICO PRELIMINAR DE OCIMUM MICRANTHUM Y EUPATORIUM ODARATUM, ESPECIES VEGETALES NATIVAS DE ESMERALDAS (ECUADOR).
Authors: Acosta Karen , Zapata Valeria , Miranda Aida , Mora José , Lajones Alfredo
Published: October 2021

El uso de plantas medicinales ha sido de gran importancia desde la antigüedad en todas las culturas. En Ecuador, la población aún usa de forma habitual plantas de forma terapéutica, como es el caso de los habitantes de Muisne, cantón localizado en la provincia de Esmeraldas. En esta investigación se realizó el estudio farmacognóstico preliminar de dos especies nativas de Esmeraldas (Ocimum micranthum y Eupatorium odoratum), a través de su análisis macromorfológico, micromorfológico, pruebas fisicoquimicas cualitativas y cuantitativas. Además, se llevó a cabo el estudio etnobotánico de estas especies. Se evidenció cualitativamente que Ocimum micranthum presenta aceites, saponinas, lactonas, cumarinas, triterpenos, esteroides, azúcares reductores, resinas, aminoácidos libres o aminas y mucílagos. En el caso de Eupatorium odoratum presentó aceites, grasas, resinas, azúcares reductores, aminoácidos libres, mucílagos triterpenos y esteroides. En consecuencia, estas dos especies presentan un potencial destacable para posteriores estudios farmacológicos.
APLICACIÓN DE PRUEBAS NO PARAMÉTRICAS PARA K-MUESTRAS PARA IDENTIFICAR CAMBIOS EN LA DISTRIBUCIÓN DEL INGRESO EN ECUADOR 2006-2016.
Authors: Roldan Liliana , Flores Miguel , Cabezas Ana
Published: October 2021

En este trabajo se analiza la distribución personal de los ingresos en distintos niveles: nacional, provincial y por actividad económica para el período 2006-2016, a partir de la información de las encuestas de hogares. Para probar si los cambios en la distribución del ingreso personal a través del tiempo son estadísticamente significativos, se aplican pruebas no paramétricas para k muestras basadas en la Función de Distribución Empírica (FDE) y la Función de Densidad de Núcleo (KDE). Los resultados muestran que, efectivamente en el período de tiempo analizado, hubo cambios en la distribución de los ingresos personales, principalmente en la localización, más que en la forma, donde las pruebas a partir de la FDE tienen un buen desempeño. En tanto que, a nivel territorial se evidenciaron cambios en la forma de la distribución como es el caso Chimborazo, donde las pruebas basadas en la KDE, como la norma L1 o el Área Común, rechazaron la hipótesis nula.
Routing of pregnant women as one of the ways to reduce infant mortality
Authors: Gorev Valery V. , Anna Anna A.
Published: October 2021

One of the most important tasks that healthcare providers face is to reduce infant mortality. The purpose of our study was to assess the effects of routing of pregnant women with preterm birth on the infant mortality rate. Materials and methods: оperating data of the Federal State Statistics Service (Rosstat), operational notifications about death of young children under the age of 1, monthly reports of obstetric hospitals subordinate to Moscow Healthcare Department, annual reports of hospital departments providing neonatal care in medical organizations of Moscow Healthcare Department, and statistical data analysis. Results and discussion. The infant mortality rate in Moscow has been declining in recent decades and has been less than 6‰ annually since 2016. The share of newborns with extremely low birth weight is insignificant in overall rate. At the same time, extremely low birth weight is one of the main causes of infant mortality. As this category of newborns requires specific care, it is better to deliver such babies in perinatal centers that provide high quality medical care. Within 5 years, the share of children with ELBW born in perinatal centers and specialized obstetric hospitals has almost doubled. At the same time, there is an increase in the survival rate of children with extremely low birth weight by the age of one year in obstetric hospitals. Conclusion. Well-planned routing of patient within the large system of obstetric hospitals in Moscow could reduce death rate, increase the survival rate of children with extremely low birth weight and contribute to reducing infant mortality in the region.
Organization of research activity in a polyclinic using medical information system
Authors: Papicheva Maria A. , Yakushina Irina I.
Published: October 2021

Introduction. The article considers an approach to organization of research activity using medical information system. Materials and methods. Authors carried out retrospective analytical cohort study of adults with temporary incapacity to work based on the data from the State Medical Institution Galichskaya District Hospital (Kostroma Region of the Russian Federation) for a period 2014–2019. Sampling was done using the medical information system. Results. As the medical information system has been operating for many years and is designed in the way that the key information gaps should be filled, we consider the results of our study on research activity in a polyclinic using medical information system successful. Discussion. The organization of research activity is discussed using results of an epidemiological study aimed at identifying the correlation between the incidence of acute respiratory diseases and further development of circulatory system diseases carried out in Galichskaya District Hospital.
Bilinçli Farkındalık (Mindfulness) ve Perinatal Ruh Sağlığı: Bir Sistematik Derleme
Authors: DAĞLAR Özge Şiir , HOTUN ŞAHİN Nevin
Published: October 2021

Giriş: Perinatal dönemde anksiyete ve depresyon gibi ruhsal sorunlar yaygındır. Bu sorunlar anne ve bebek sağlığı açısından birçok olumsuz sonuçlara yol açabilmektedir. Gebe ve emziren kadınlar için psikotrop ilaç kullanımıyla ilişkili potansiyel riskler nedeniyle bu kadınlara farmakolojik olmayan yaklaşımlar ile destek sağlamak önemlidir. Bilinçli farkındalık temelli uygulamaların perinatal ruh sağlığı sorunlarının çözümünde yeni bir yaklaşım olduğuna dair bilgiler olsa da etkinlikleri hakkında yeterli kanıtlar bulunmamaktadır.Amaç: Bu derlemenin amacı perinatal ruh sağlığını desteklemek amacıyla gebelik ve doğum sonrası dönemde bilinçli farkındalığın (mindfulness) etkinliği hakkında güncel bilgi ve çalışmaları sistematik olarak analiz etmektir.Yöntem: Literatür taraması, Ocak 2016 - Nisan 2021 tarihleri arasında yayınlanmış çalışmaları içermektedir. Literatür taraması için “Mindfulness”, “Meditation”, “Pregnancy”, “Prenatal”, “Perinatal” ve “Postpartum” anahtar kelimeleri kullanılmıştır. Google Scholar, PubMed, Cochrane ve Science Direct veri tabanlarında tarama yapılmıştır. Tarama sonucunda 18.250 yayına ulaşılmış olup, kriterleri sağlayan 16 çalışma derleme kapsamına alınmıştır.Bulgular: İncelenen çalışmaların sonucuna göre gebe kadınlara uygulanan sekiz haftalık bilinçli farkındalık temelli programların gebelerdeki algılanan stres, anksiyete ve depresif belirtiler ile postpartum depresyon düzeyini azalttığı belirlenmiştir. Bilinçli farkındalık temelli programların gebelerin bilinçli farkındalık ve kendine şefkat düzeylerini artırdığı görülmüştür.Sonuç: Bilinçli farkındalık temelli uygulamalar perinatal dönemde stres, anksiyete ve depresyon düzeyini azaltmakta, bilinçli farkındalık düzeyini artırmaktadır.