bluuebunny/crossref_metadata_2025 huggingface dataset:
La atracción en la elección de pareja
Authors: Puma Simbrón Hellen
Published: August 2024

El objetivo de la investigación es analizar el papel que cumple la atracción en la elección de la pareja y los factores que están involucrados en el contexto social. Se trata de un artículo de revisión teórica. Se presenta al atractivo físico como un elemento importante a la hora de elegir una pareja, ya que impacta de manera positiva en las personas y esto abre mayores oportunidades; sin embargo, se debe tener en cuenta que el concepto de belleza depende del con- texto social y cultural. Se concluye que la atracción es el punto inicial al momento de elegir una pareja, esto involu- cra el atractivo físico y otros factores similares; sin embargo, debe considerarse también el contexto social (cultura, costumbres, valores, principios) que rodea a cada individuo, ya que eso influye en su concepto de lo que es bello.
Editorial
Authors: Miranda Limachi Keila Ester
Published: August 2024

Editorial
Deconstrucción cristocéntrica como método bíblico
Authors: Canale Bacchiocchi Silvia
Published: August 2024

El objetivo de este estudio es revelar los beneficios positivos del posmodernismo, particularmente al mostrar que la deconstrucción de Jacques Derrida contiene elementos útiles para una deconstrucción bíblicamente fiel y centrada en Cristo de las tradiciones teológicas cristianas. Además, este artículo quiere mostrar que tal deconstrucción bíblicamente orientada no solo es beneficiosa para la iglesia cristiana, sino que es el único método que conducirá a una mayor claridad sobre las doctrinas actuales y la recepción de una mayor luz. Estemétodo no es una deconstrucción aplicada a la Escritura sino de la Escritura a las interpretaciones, creencias y prácticas cristianas tradicionales.
Elena G. de White y los idiomas bíblicos originales
Authors: Richter Eric E.
Published: August 2024

Una adecuada interpretación del texto bíblico requiere un detallado análisis exegético de sus idiomas originales: hebreo, arameo y griego. Las traducciones a idiomas modernos son incapaces de transmitir algunos matices de estos lenguajes, provocando que el lector no pueda percibir algunos detalles. En la presente investigación se muestra que la escritora cristiana Elena G. de White, a pesar de desconocer los idiomas bíblicos originales, transmitió en sus escritos detalles y matices presentes en el texto hebreo y griego de la Biblia. Se estudia Éxodo 5:5, Mateo 2:9 y Romanos 16:7, mostrando cómo la interpretación que Elena G. de White dio de estos textos revelan ciertos matices propios del texto bíblico original.
Revisando algunas tendencias teológicas e intelectuales contemporáneas
Authors: Moskala Jiří , Iparraguirre Joel
Published: August 2024

Este artículo examina las tendencias teológicas e intelectuales contemporáneas que desafían la percepción de la religión, especialmente en el contexto cristiano. Explora ataques recientes al carácter de Dios y la religión por parte de figuras prominentes como Richard Dawkins y Sam Harris, que utilizan argumentos de la ciencia y el neoteísmo para criticar la fe religiosa. El artículo también analiza el resurgimiento del interés por las interpretaciones patrísticas de las Escrituras, el debate sobre la doctrina del infierno, la creciente defensa del universalismo, y el atractivo del catolicismo romano para algunos evangélicos. Finalmente, aborda la espiritualidad moderna como una búsqueda de experiencias trascendentales, destacando la importancia de una representación auténtica del carácter de Dios frente a un mundo relativista.
MODELING OF THE CUTTING FORCES IN END MILLING OF A METALLIC MULTILAYER MATERIAL
Authors: Župerl Uroš , Kovačič Miha
Published: August 2024

Multilayer metal materials are increasingly used by tool shops in the production of transfer tools for sheet-metal forming. In research, it is found that during the machining of these advanced materials, damage to the cutting edge often occurs due to jumps in the cutting forces. The size of the cutting forces when milling a multi-directionally layered metal material is influenced by both the direction of depositing the individual layer and the geometry of the cutting tool. The main goal of the research was to create a mechanistic model of cutting forces for the end-milling of unidirectional and multidirectional 20MnCr5/316L four-layered metal material. The results of the model were compared with experimental data, where a good agreement was found when milling unidirectional layered material and a slightly worse agreement when milling multidirectional material. The maximum observed deviation of the predicted cutting forces is 14.6 % for all the comparative tests.
TRIBOLOGICAL AND MECHANICAL CHARACTERIZATION OF AL6060/SI3N4/BN HYBRID ALUMINIUM METAL MATRIX COMPOSITES
Authors: Pandurengan Jai Rajesh , Venkatesan Balambica , Munuswamy Achudhan
Published: August 2024

In recent years, aluminium-based composites have emerged as preferable substitutes for conventional aluminium alloys in various contemporary applications, like the aerospace and automotive industries. This shift can be attributed to their enhanced characteristics and superior properties. Improved strength-to-weight ratio, reduced thermal expansion, and superior wear resistance are just a few of the benefits. Several researchers have created aluminium metal matrix composites (AMMCs) by combining various ceramic reinforcing elements with aluminium alloys. Ceramic reinforcing materials increase the strength, hardness, and wear resistance. The aim was to enhance the mechanical and wear characteristics of a composite material, i.e., to find the mechanical characteristics of an Al6060/BN hybrid alloy, such as tensile strength, impact, hardness, etc. The composites were developed by incorporating silicon nitride (Si3N4), a hard ceramic material, as the main reinforcing component, along with boron nitride (BN), a solid lubricant, as the secondary reinforcement. The stir-casting technique was employed to fabricate aluminium metal matrix composites with varying weight fractions (0, 5, and 10) w/% of Si3N4 and BN. Tensile and hardness tests were conducted to analyse the basic mechanical properties of the resulting composites.
INVESTIGATION OF THE MECHANICAL AND TRIBOLOGICAL BEHAVIOURS OF CUPOLA SLAG AND MWCNT-REINFORCED EPOXY HYBRID NANOCOMPOSITES: A SUSTAINABLE APPROACH FOR ENVIRONMENTAL PRESERVATION
Authors: M. Rajeswaran , P. Prathap , S. Kannan , T. A. Sundaravadivel
Published: August 2024

This experimental investigation explores the mechanical and tribological characteristics of cupola slag (CS) and multiwall carbon nanotubes (MWCNTs) reinforced hybrid nanofiller epoxy composites. Cupola slag is an industrial by-product that is generated during the melting of cast iron. The disposal of slag residues in landfills results in environmental pollution. In the context of environmental preserving as well developing new engineering composites material from waste to resource. MWCNTs possess an excellent strength-to-weight ratio, high stiffness, and thermal properties. The mechanical and tribological characteristics of the hybrid nanocomposites comprising epoxy were examined by varying the weight fraction of fillers composed of CS and MWCNTs. The experimental results indicated that the ECSM3 hybrid nanocomposites have superior tensile strength and the flexural modulus improved by 92 % and 78 % respectively when compared with epoxy. Similarly, the tribology performance of the ECSM3 exhibited improved specific wear resistance of 97 %, 106 % and 88 % on the dry-sliding loads of 10 N, 20 N and 30N, respectively. A morphological analysis was carried out on fractured and worn surfaces of the specimen to understand the homogeneous dispersion and matrix-interlocking mechanism between the hybrid nanofillers and the epoxy matrix. The integration of CS alongside MWCNTs for the fabrication of epoxy hybrid nanocomposites represents a stride towards sustainable and eco-friendly technology in the production of multifunctional composite materials for diverse engineering applications.
Análise do potencial de ganho financeiro por meio de créditos de carbono com a implantação de biodigestores no sistema de disposição de Resíduo Sólido Urbano em Campo Grande – MS
Authors: Ferrari Gabriel Mathias , Mello Nilvania Aparecida de
Published: August 2024

O aumento do consumo de recursos naturais crescente nos últimos anos trouxe como um dos resultados o problema de se pensar “o que fazer com o lixo”. Com o aumento populacional, é progressivo o número de aterros que são criados para a disposição dos resíduos, deixando para a sociedade estes passivos ambientais. Esta pesquisa procurou analisar, dando continuidade a outros trabalhos já realizados, uma forma alternativa de ganho financeiro no processo de implantação de um sistema de biodigestor no município de Campo Grande – MS. Desta forma, além de diminuir impacto no meio ambiente, por meio do tratamento de parte dos resíduos que seriam despejados no aterro, buscou-se identificar o potencial de ganho por meio da geração e comercialização de crédito de carbono. Considerando dois cenários, um otimista e um pessimista, foi possível identificar que em ambos os casos é vantajoso a adoção do sistema de geração de créditos de carbono no sistema de aproveitamento do biogás por meio de biodigestores no município analisado, sendo estes ganhos formas alternativas, não principais, do processo de tratamento dos resíduos sólidos urbanos.
Crystallisation protocol for SARS-CoV-2 nsp3 macrodomain in P1 21 1 v1
Authors: Aschenbrenner Jasmin , Marples Peter , Koekemoer Lizbé , Tomlinson Charlie , Fearon Daren
Published: August 2024

The COVID-19 pandemic has demonstrated the need for novel therapeutic interventions and improved pandemic preparedness strategies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This protocol details an optimized crystallization method for the SARS-CoV-2 nsp3 macrodomain, a potential drug target. Using sitting drop vapor diffusion with seeding, we describe specific buffer conditions and procedures to consistently produce high-quality crystals suitable for XChem fragment screening. The method yields crystals that diffract to an average resolution of 1.5 Å, enabling high-resolution structural studies and can also be used for compound development through co-crystallization experiments. All structures solved during the development of tool compounds for the SARS-CoV-2 nsp3 macrodomain are deposited on the PDB (Group deposition: G_1002283).
Co-crystallisation protocol for SARS-CoV-2 nsp3 macrodomain in P1 21 1 with ligands v1
Authors: Aschenbrenner Jasmin , Marples Peter , Fearon Daren
Published: August 2024

The COVID-19 pandemic has demonstrated the need for novel therapeutic interventions and improved pandemic preparedness strategies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This protocol details an optimized crystallization method for the SARS-CoV-2 nsp3 macrodomain, a potential drug target. Using sitting drop vapor diffusion with seeding, we describe specific buffer conditions and procedures to produce high-quality crystals of ligand-bound nsp3-mac. All structures solved during the development of tool compounds for the SARS-CoV-2 nsp3 macrodomain are deposited on the PDB (Group deposition: G_1002283).
Applying the Mitosis-enabled Anchor-away/Recruiter System (MARS) for conditional protein recruitment to the plasma membrane during mitosis v1
Authors: Cao Xiaofu , M Baskin Jeremy
Published: August 2024

Tools for acute manipulation of protein localization enable elucidation of spatiotemporally defined functions, but their reliance on exogenous triggers can interfere with cell physiology. This limitation is particularly apparent for studying mitosis, whose highly choreographed events are sensitive to perturbations. Here we exploit the serendipitous discovery of a phosphorylation-controlled, cell cycle-dependent localization change of the adaptor protein PLEKHA5 to develop a system for mitosis-specific protein recruitment to the plasma membrane that requires no exogenous stimulus. Mitosis-enabled Anchor-away/Recruiter System (MARS) comprises an engineered, 15-kDa module derived from PLEKHA5 capable of recruiting functional protein cargoes to the plasma membrane during mitosis, either through direct fusion or via GFP–GFP nanobody interaction. This protocol outlines the cloning strategy to generate MARS-POI and GFP-POI fusion constructs, procedures to examine POI recruitment by MARS via transient transfection, and steps to generate cell lines stably expressing 2xMARS-nGFP.
SOP for Endoscopy Collection v1
Authors: Bi Joanna
Published: August 2024

SOP for Endoscopy Collection
İzmir'i etkileyebilecek büyük depremlerin makine öğrenimi yöntemleriyle tahmin edilmesi
Authors: Doğan Ayhan
Published: August 2024

Deprem, üzerinde yaşadığımız dünya üzerindeki en büyük doğal afetlerdendir. İnsanlık tarihten günümüze depremlerden dolayı çok sayıda can ve mal kaybı yaşamıştır. Bu nedenle tarih boyunca insanlar depremleri önceden tahmin edebilmek ve önlemler alabilmek için çeşitli çalışmalar yapagelmiştir. Ancak dünyamızın karmaşık jeolojik yapısı ve çeşitli dinamikleri nedeniyle depremleri tahmin etmek oldukça zordur. Yapay zeka çalışmalarında son yıllarda meydana gelen gelişmeler sayesinde birçok alanda yeni çözümler ortaya çıkmaya başlamıştır. Bu çalışmada diğer çalışmalardan farklı olarak gelecekte İzmir ilini etkileyebilecek 6 ve üzeri büyüklükteki depremlerin odak konumları ve odak derinlikleri Random Forest (RF), Decision Tree (DT), Light Gradient Boosting Machine (LGBM), Category Boosting (CB), Support Vector Machine (SVM) makine öğrenimi yöntemleri kullanılarak tahmin edilmiştir. Girdi verisi olarak 1900-2023 arasındaki deprem katalog verileri ile Gutenberg-Richter yasasına göre bu verilerden üretilen a ve b katsayıları birlikte kullanılmıştır. Sonuçlar RMSE, MAE ve R2 metrikleriyle değerlendirilmiştir. Gelecekte İzmir’i etkileyebilecek depremlerin tahmin edilen odak konumları ve derinlikleri tablo halinde verilmiş ve harita üzerinde gösterilmiştir.
Digestible Information is Remembered Information
Authors:   , Meyers Emma Nicole , Nicholas Diana S.
Published: August 2024

The goal of this thesis project is to increase access to academically rigorous research by providing tools to promote information literacy. In order to do this, the present thesis has two objectives: the first is to better understand the landscape of information source usage, and the second is to design solutions to increase access to high-quality, academically rigorous information in a digestible way. Through surveys and literature review, this thesis aims to explore what sources are most utilized, what are common perceptions of these sources in terms of accessibility and utility, and to see if perceived accessibility and utility correlate with information source use. Understanding current information source usage is key to finding new ways to disseminate academically rigorous information because knowing this problem area makes it easier to identify which strategies would work best for research dissemination design. Utilizing in-depth interviews with professors, librarians, researchers, and students, this project then aims to illuminate additional areas of the research generation and dissemination process, where access can be improved, and where potential directions for design solutions could be. The thesis closes with a design for a "synthesis page" which combines findings from the literature review, interviews, and surveys to create an extension that can teach the user how to understand the different parts of an academic article while creating a central place with resources pertaining to the topics within the article. The goal of the page is to provide a method for reorganizing the way academic research is communicated digitally in order to improve access and understanding.
Proteogenomic Discovery of Immunotherapeutic Targets in Cancer
Authors:   , Shraim Rawan , Wheatley Margaret A.
Published: August 2024

Cancer is a genetic disease characterized by abnormal cell growth and metastases and remains a leading cause of mortality globally. Chemotherapy and other traditional treatments often result in adverse effects, necessitating the development of targeted and less toxic approaches, such as immunotherapies. Immunotherapies harness the immune system to fight diseases. A challenge in developing targeted immunotherapies such as adoptive cell therapies and monoclonal antibodies is the identification of cancer specific surface expressed proteins or antigens. Rhabdomyosarcoma (RMS) is the most common soft tissue cancer diagnosed in children, adolescents, and young adults, comprising 3-4% of all childhood cancers. Treatment is commonly multi-modal involving surgery, radiation, and chemotherapy and has not substantively changed over the last four decades. Approximately 90% of patients with localized low-risk disease are cured with multi-modal therapy; however, the survival rate for patients with metastatic disease remains mired at 30% or less and relapsed disease is typically lethal. There are currently no approved immunotherapies or targeted therapies for RMS and there have been no significant improvements in survival outcomes for RMS patients despite multiple randomized controlled trials of various chemotherapy combination. To address the challenge of identifying and systematically prioritizing immunotherapeutic targets computationally, we developed IMMUNOTAR. IMMUNOTAR integrates user-provided expression data with features extracted from multiple publicly available databases and quantitively prioritizes potential surface protein targets based on predefined optimal immunotherapeutic target criteria. Both adult-derived and pediatric-specific databases are included within IMMUNOTAR. To address the challenge of identifying immunotherapies specifically in RMS, we generate a surface mass-spectrometry dataset to profile surface proteins within RMS subtypes and applied IMMUNOTAR to identify potential immunotherapeutic targets within this cohort. We hypothesize that a computational approach that integrates various public databases that tackle the ideal immunotherapeutic criteria can aid in identifying target candidates and that applying this methodology to surface-protein specific data generated from RMS will identify and prioritize surface proteins preferentially expressed in RMS, or RMS subtypes, to undergo further functional validation as a candidate immunotherapeutic target. Through our work, we were able to validate IMMUNOTAR's applicability across various cancer phenotypes by replicating results obtained by other groups who used more manual scoring algorithms to identify and validate immunotherapeutic targets within Ewing's sarcoma and multiple myeloma. Additionally using our RMS data, we were able to identify glypican 2 (GPC2) as potential immunotherapeutic target. Preclinical testing of GPC2 targeted immunotherapy showed that it was efficacious in eradicating RMS tumors.
Investigating the antimicrobial activity of neem and clove extract on biofilm-producing oral microflora
Authors: Bhattacharya Tanushree , Saha Rudra Prasad , Majumder Rajib , Ghosh Sanmitra
Published: August 2024

Periodontal disease, a serious gum infection, is reported to be widespread in the Indian population. A heterogeneous microbial population, predominantly consisting of gram-negative anaerobes such as Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Porphyromonas intermedia, is associated with periodontal plaque formation. This condition may be worsened by the invasion of soft tissues by different species of Candida. Natural products like clove (Syzygium aromaticum) and Neem (Azadirachta indica) are very popular and easily available in the Indian climate and have great potential in preventing periodontitis. Azadirachta indica (Neem) exhibits versatile modes of action, including reported antimicrobial effects against several species associated with periodontal disease. Therefore, this study aims to detect the antimicrobial and antifungal effects of Neem and clove on oral biofilm both before and after biofilm formation. Results of the study revealed that both neem and clove crude extracts and their different dilution showed a significant reduction in the growth of fungal strains (Candida sp.) isolated from oral samples from people with poor hygiene and the biofilm produced by them.
The Benefit of Warning to Improve Detecting Social Engineering Attack Messages
Authors:   Department of Information and Computer Science, College of Computer Science and Engineering, University of Ha’il, Ha’il, Saudi Arabia, Alseadoon Ibrahim Mohammed
Published: August 2024

Social engineering attack messages are a constant threat to online services. Numerous scholars have attempted to solve this problem by understanding the interaction between users and social engineering attack messages. Users’ behavior and traits are crucial in making them immune to attacks. Specifically, studies have indicated that the mental process of detection has a tremendous effect on preventing users from becoming victims of attacks. Studies have also suggested that users need to think in a certain way to detect deception. Our study aims to determine the impact of warnings on users’ types of thinking to increase secure behavior. A mixed-method approach is applied (i.e. experiment and open-ended questions) to answer research questions. The results indicate that warnings impact users’ types of thinking and have a significant impact on increasing their protection against attacks. In addition, warnings have the benefit of confirming users’ initial judgment of known (familiar) social engineering attack messages without the need to perform deep thinking to identify deception. Additionally, users employ several methods to validate messages. Warning has an effect on these methods.
Revolutionizing Pedagogy: The Influence of H5P (HTML5 Package) Tools on Student Academic Achievement and Self-Efficacy
Authors:   Department of European Languages, School of Foreign Languages, University of Jordan, Amman, Jordan, Rayyan Mohammad
Published: August 2024

As a new tool in the field of educational technology, H5P appears to have the potential to teach a second language (L2). This study aims to highlight the potential direction of upcoming teaching methods, sparking informed choices in educational approaches and guidelines by evaluating both the concrete and abstract results of incorporating H5P. To this end, this study compared H5P tools to conventional teaching methods to determine how they affected students’ grades and confidence in learning German as a second language. The participants were split into two main groups: the control group and the experimental group. A noticeable difference in grades between these groups was demonstrated by our main findings, which were derived from a conventional t-test. This was further demonstrated by a different test, the Simple Linear Regression. According to the data, students who used H5P tools in the experimental group saw an increase in their self-confidence scores, whereas the scores of the control group slightly decreased. This change was supported by a second test, the Analysis of Covariance (ANCOVA). This research firmly backs the claim that H5P tools can increase academic achievement and student confidence. Consequently, it suggests that educators should contemplate integrating these tools into their teaching practices to enhance overall classroom results.
Practicality of Mobile-Based Learning with Project-Based Learning Approach in Electric Motor Installation to Increase Student Learning Motivation
Authors:   Electrical Engineering, Faculty of Engineering, Padang State University, Padang, Indonesia, Sardi Juli
Published: August 2024

Opportunities for innovation in leveraging mobile devices for learning and integrating them with diverse learning methodologies are emerging due to the rising prevalence of mobile device usage among students, so this research investigates the practicality of mobile-based learning using a project-based learning approach in the context of electric motor installations which aims to increase student learning motivation. This research aims to examine the impact of an integrated approach on student’s practical skills and motivation in electric motor installation education. The research methodology used in this research adopts a Research and Development (R&D) framework with a 4D model, which includes the define, design, develop, and disseminate stages. In this study, we carefully designed the app navigation, user interface, and mobile functionality, followed by validation, practical testing, and assessment of student motivation. Validation assessments are carried out by education and technology experts. Practicality assessment is carried out by user testing. A motivation assessment is carried out using a motivation questionnaire. The research results confirm that mobile-based learning with a project-based learning approach in learning electric motor installation meets the criteria for validity and practicality in all aspects. In addition, this integrated approach has proven to be very effective in increasing student learning motivation. Based on research findings, this integrated approach provides benefits in the form of ease of collaboration, access to material, interaction, more interactive visualization, efficiency of learning time, and self-evaluation. However, the integrated approach currently being developed is not yet integrated with Artificial Intelligence (AI), so there is still a great opportunity for further research in its integration with education.
Smoking and its Impact on Orthodontic Treatment/Management Modalities: A Systematic Review and Meta-Analysis
Authors: Alam Mohammad Khursheed , Almutairi Haifa Ali , Barayan Rowida Saleh , Abutayyem Huda , Alswairki Haytham Jamil , Alfawzan Ahmed Ali , Hajeer Mohammad Younis , Albalawi Ahmed Saleh , Alruwaili Khalid Hussain Ali , Issrani Rakhi , Prabhu Namdeo
Published: August 2024

Background: We aimed to review studies that evaluated the effect of cigarette smoking on orthodontic treatment methods and determine whether the smoke affected appliances in a way that could impair the effectiveness of the overall treatment strategy.
Methods: PubMed, Google Scholar, Cochrane Library, and Web of Science were scoured using pertinent keywords, reference searches, and citation searches in accordance with the PRISMA protocol regarding articles published from 2008 till 2022.
Results: Ultimately, 7 papers were chosen for further analysis at the end of the selection protocol. Overall pooled odds ratio (OR) for the impact of cigarette smoking on orthodontic treatment was 0.25 (95% CI: 0.15, 0.43), with high statistical significance (P<0.00001) but also high heterogeneity (I² = 81%). The relative risk (RR) was 0.50 (95% CI: 0.38, 0.66), indicating a 50% greater risk of noticeable impact, with high statistical significance (P<0.00001) and high heterogeneity (I² = 79%), and the risk difference (RD), which was -0.33 (95% CI: -0.45, -0.21), suggesting a 33% higher risk of noticeable impact, with high statistical significance (P<0.00001) and high heterogeneity (I² = 81%). The high heterogeneity in all measures indicates significant variability in the results across the included studies.
Conclusion: All the 7 studies selected for our systematic review exhibited significant detrimental associations between smoking and orthodontic appliances and other modalities that were exposed to cigarette smoke. However, more studies need to be done in this regard, since the literature currently available on this relationship is quite poor and lacking in concrete evidence.
Efficacy and Safety of Autologous Cytokine-Induced Killer (CIK) Cellular Immunotherapy Combined with Chemotherapy in Non-Small-Cell Carcinoma (NSCLC): A Meta-analysis
Authors: Zhong Cheng , Tang Haowei , Wang Qun
Published: August 2024

Background: To investigate the efficacy and safety of autologous Cytokine-induced killer (CIK) cellular immunotherapy combined with chemotherapy for non-small-cell carcinoma (NSCLC).
Methods: The literature related to the efficacy and safety of autologous CIK cellular immunotherapy combined with chemotherapy in NSCLC were collected. The Chinese literature databases were collected from CNKI, Wanfang and Weipu, and the English literature were retrieved from Cochrane Library and PubMed. All literature were retrieved until the year of 2022, and evaluated by its method quality and analyzed by RevMan5.3 software.
Results: A Meta-analysis on the 11 included literature showed that the treatment efficacy and disease control rate (DCR) of patients in the observation group were significantly higher than those in the control group (P＜0.05), and significantly increased the levels of CD3+, CD4+, CD4+/CD8+ indexes than the control group (P＜0.05), and the incidence of bone marrow suppression, liver injury and gastrointestinal symptoms were significantly lower than those of the control group (P＜0.05).
Conclusion: Compared with single chemotherapy, CIK combined with chemotherapy in the treatment of patients with NSCLC can improve the efficacy of treatment and DCR, significantly improve their immune function, reduce the incidence of adverse reactions, and is beneficial to the recovery of prognosis.
Evaluation of Screening Results for Vancomycin-Resistant Enterococci: Three-Year Surveillance
Authors: Ayaydın Zeynep , Azarkan Ayşe Batgi , Bilik Özge Alkan , Tekin Ali Cem
Published: August 2024

Background: Enterococci are facultative anaerobic, binary, or chained Gram-positive cocci. The gastrointestinal colonization of hospitalized patients is the most important reservoir of vancomycin-resistant enterococci. We aimed to evaluate retrospectively the screening results of vancomycin-resistant enterococci, studied by the simultaneous (real-time) polymerase chain reaction method on rectal swabs of adult and pediatric patients hospitalized in our hospital in 2019-2021.
Methods: Adult and pediatric patients were included in our study between Jan 2019 and Dec 2021. The results of vancomycin-resistant enterococci, studied with the real-time polymerase chain reaction method from rectal swabs sent from intensive care units and services, were analyzed retrospectively. Isolation of the samples was performed using the Fluorion VRE QLP 1.0 real-time polymerase chain reaction kit (Iontek, Turkey), and detection was performed with the Fluorion Detection System (Iontek, Turkey) real-time polymerase chain reaction device.
Results: Overall, 31,725 patients were included in our study. When evaluated in order of years, in 2019, 379 (7%) of 5,389 adults, 322 (7.4%) of 4,003 children, 234 (5.5%) of 4,185 adults in 2020, 157 (2.4%) of 6,499 children, and in 2021, vancomycin-resistant enterococci were detected in 469 (7.5%) of 6,232 adults and 224 (4.1%) of 5,417 children.
Conclusion: The prevalence of vancomycin-resistant enterococci is greater in adults, particularly in intensive care units, compared to children. Infection control precautions and training be augmented in high-risk clinics, while the unnecessary utilization of glycopeptides should be limited.
Mediterranean Diet Adherence and Eating Disorders Screening in Adults with Celiac Disease in Morocco
Authors: Ibrahmi Btihaj AL , Bour Abdellatif
Published: August 2024

Background: Celiac disease is a chronic autoimmune disease of the small intestine, related to gluten intolerance occurring in genetically predisposed patients. This study aimed to evaluate Mediterranean diet adherence, screen eating disorders and establish the relationship between Mediterranean diet and eating disorders.
Methods: This study included 81 adults with celiac disease, and 85 without celiac disease from Rabat-Sale-Kenitra hospitals between May 2022 and Nov 2022. The Mediterranean Diet Serving Score (MDSS) questionnaire was used to determine adherence to the Mediterranean diet and SCOFF questionnaire was used to screen eating disorders.
Results: The results showed a significant difference between the two groups in age (P=0.000), weight (P=0.041), height (P=0.000) and non-adherence to Mediterranean diet (P=0.032). Participants without celiac disease reported a significantly (P=0.032) lower adherence score to the Mediterranean diet (62.35%) than participants with celiac disease (29.62%). Additionally, the results of the Khi2 test which revealed a significant association between MDSS and SCOFF (P=0.024). In addition, based on logistic regression the Mediterranean diet Serving Score was significantly associated with eating disorders (P=0.025) in adults with celiac disease, on the other hand, weight, height, BMI and MDSS were significantly associated with eating disorders in adults without celiac disease.
Conclusion: Our study showed good adherence to the Mediterranean diet by celiac adults so it can be assumed that the Mediterranean diet could have a protective effect against eating disorders in celiac patients.
The Effect of Virtual Patient Visits in the Intensive Care Unit on Postpartum Depression
Authors: Kaynak Serap , Yılmaz Hatice Bal , Çağlar Atika , Özdil Mine
Published: August 2024

Background: Maternal postpartum depression negatively affects the baby's emotional, behavioral, and cognitive development and attachment pattern. We aimed to examine the effect of virtual patient visits    in neonatal intensive care unit on postpartum depression in mothers.
Methods: Research data were obtained from mothers whose preterm infants were hospitalized in the neonatal intensive care unit between April and December 2022. A total of 100 mothers of preterm infants (50 in the virtual patient visit and 50 in the control group) treated in the neonatal intensive care unit of a hospital constituted the sample of the study. Using the Zoom application, virtual patient visits were made for 5 minutes, seven days a week, between mother and the preterm infants, with no nursing intervention implemented for at least 30 minutes. Mothers in the control group saw their babies face to face two days a week. In standard hospital procedure, mothers saw their babies twice a week. Edinburgh postpartum depression scale (EPDS) was administered online to the all mothers before and after the study.
Results:The research resulted with statistically significant decreased EPDS scores of the mothers in virtual patient visit group with the pre-study scores. A statistically significant decrease was found compared to the control group (P<0.001).
Conclusion: Virtual patient visits between preterm infants in neonatal intensive care unit and their mothers could be effective in preventing or reducing postpartum depression of the mother.
Evaluating the Governance Ability of Urban Public Health Us-ing EM–AHP–TOPSIS Method: A Case Study in China
Authors: Shou Yijun , Shou Jixia
Published: August 2024

Background: Evaluating the governance capacity of urban public health is the key to improving the level of urban public health. We aimed to evaluate the governance ability of urban public health.
Methods: An index system of governance ability of urban public health was established. The governance ability of urban public health was evaluated, and major constraints against the ability improvement were analyzed through the EM (Entropy Method)–AHP (Analytic Hierarchy Process)–TOPSIS (Technique for Order Preference by Similarity to an Ideal Solution) model and data of urban agglomeration in Yangtze River Delta, China in 2023.
Results: Shanghai, Nanjing, Hangzhou, Suzhou, and Ningbo rank top 5 in terms of governance ability of public health, and they are in the first echelon. Hefei, Yancheng, Wuxi, Taizhou and Shaoxing rank 6–10, and they are in the second echelon. The remaining 17 cities are in the third echelon. Major sources of governance ability of urban public health and major factors that decrease governance ability are Medical Facility (A12), Health Improvement (A33), Medical Staff (A13), Government Ability (A11), and Health Loss (A34). For urban agglomeration in Yangtze River Delta, China, public health foundations, environmental exposure risks, public health performance, and public health emergencies all can influence the governance ability of public health.
Conclusion: Accurate evaluation of the governance ability of urban public health can provide guidance and policy propositions to improve the governance system of public health and improve the emergency coordination ability of the government.
Public Health Risk from Influenza Viruses: A Scientometric Analysis of Influenza Research
Authors: Ahmad Naved , Amees Mohammad , Alam Abid Fakhre , Ahmed Shaikh Mujeeb , Hossain Saddam , Khan Jalaluddin , Raihan Mahfuz , Alotaibi Abdulmueen , Khan Diwan Israr , Taher Ali Mohammed
Published: August 2024

Background: Seasonal influenza and novel H1N1 influenza from 2009 present worldwide difficulties for public health sectors. It is difficult to distinguish between significant research output due to the rising quantity of papers mentioning this infectious disease. We aimed to identify a scientometric analysis of influenza diseases. We aimed to highlight the progress made in the discipline by the researchers affiliated with most documents.
Methods: The h-index was used to evaluate the publication performance of highly cited papers. We retrieved the scientometric data using the keywords “Influenza” OR “Flu” OR “Orthomyxoviridae” AND “Antiviral agents” OR “Antiviral drugs.” In all, 59013 documents were retrieved from the Web of Science between 2011 and 2020. The exported data to Biblioshiny and Microsoft Excel tools included sources by year, active authors, active journals, and countries. Also, we made use of quantitative analysis with scientometric indicators and knowledge mapping through the VOSviewer visualization software for creating the network visualization maps.
Results: We found most papers written in English and other languages were from 402027 authors and listed in 4443 core journals. The researchers found that Palese P produced 155 and received an h-index of 55. The author Li Y has the highest contributions, with 313 publications. In global influenza research, Europe and North America are the most productive and impactful continents. The influenza research has been published in very few journals.
Conclusion: This study will help hospital librarians and other library professionals to understand the status of research on influenza at any given point in time.
Photobiomodulation Therapy for Improvement of Body Contour: A Retrospective Study on Middle Eastern Participants
Authors: Eskandari Seyed Ebrahim , Samadi Aniseh , Kardeh Sina , Dowlati Yahya , Ahmadian Yazdi Hasti , Firooz Alireza
Published: August 2024

Background: The rising demand for body contouring and concerns about side effects of invasive surgical procedures have led to advances in providing new non-invasive alternative methods for weight reduction. The current retrospective study investigated the safety and efficacy of photobiomodulation technology in reducing local obesity in Middle Eastern participants.
Methods: Providing data about body circumferences of 30 participants, with body mass index (BMI) >28 and localized obesity in the abdomen, thighs, buttocks, or arms were included in the final data synthesis. All the records were received at least 4 treatment sessions with the photobiomodulation technology (Volcano device) in Center for Research and training in Skin Diseases and Leprosy (CRTSDL) during June 2022-September 2022  Reductions in body standing circumferences as well as reported adverse effects and participants’ satisfaction were retrospectively evaluated and reported.   . 
Results: The extricated data included 30 females participants aged 42.06 ± 11.6 years and localized obesity in the abdomen (15 cases), thighs (7 cases), hip (one case) and arms (7 cases). While BMIs were not significantly different from the baseline, abdominal, arm and tight circumferences showed a significant decline after receiving 4 and 6  treatment sessions (P<0.01).. There was no report of adverse effect and overall satisfaction was an "excellent" grade
Conclusion: This study demonstrated the effectiveness and safety of photobiomodulation in reduction of circumferential size in abdomen, buttock, thigh, and arm areas in Middle Eastern participants with high patient satisfaction and acceptable safety profile.
Bone Mineral Density, Osteoporosis Prevalence and Influential Factors in Osteogenesis in Patients with Beta Thalassemia Major: A Cross-Sectional Study
Authors: Behzadifard Saba , Arianezhad Ali , Nazarinia Donya , Behmanesh Roya , Sinaei Hosein , Dezfuli Davood Alinezhad , Behzadifard Mahin
Published: August 2024

Background: Osteoporosis and osteopenia considered as severe problems in Beta thalassemia major (BTM) that can lead to bone fractures. We aimed to investigate bone mineral density status and the laboratory parameters related to bone metabolism in BTM patients and compare the statically differences between the mentioned parameters in the patients with or without bone fractures.
Methods: The results of laboratory parameters including; Hemoglobin (Hb), Calcium (Ca), Vitamin D (Vit D), Phosphorus (P), Magnesium (Mg), Alkaline Phosphatase (ALP), Ferritin (FER), Serum Iron (SFe), Thyroid Stimulating Hormone (TSH), T3, T4 and Parathyroid Hormone (PTH), and BMD (by using Dual-Energy X-ray Absorptiometry (DEXA) method) were investigated in 143 BTM patients from thalassemia center of Dezful University of Medical Sciences in 2023.
Results: Seventy-two women and 71 men with confirmed BTM diagnosis with age range (32.4 ± 9.7) were entered in the study. Laboratory parameters including TSH, T3, T4, ALP, FER 247) and SFe showed a significant difference between fracture and non-fracture groups respectively (P≤0.05). In this study, Z-Score between -1.1 and -2.4 was considered osteopenia, and below -2.5 was osteoporosis. Among the studied patients 36.6%, 39.1% and 24.2% had normal bone density, osteopenia and had osteoporosis respectively.
Conclusion: Osteopenia and osteoporosis had a high frequency among the studied patients that can prone them to bone fractures. Continuous examinations of laboratory tests, especially T3, T4, TSH, FER, SFE, can be helpful for faster diagnosis and therapeutic interventions to prevent the occurrence of osteopenia and pathological fractures.
Social Media and Adolescents (Opportunities and Threats): A Letter to Editor
Authors: Rahaei Zohreh , Rastjoo Saeideh
Published: August 2024

The Article Abstract is not available.
COMMENT on “Trend Analysis of Suicide Mortality and Years of Life Lost From 2016 to 2021 in Southern Iran”
Authors: Jalilian Mohammad
Published: August 2024

The Article Abstract is not available.
SURFACE PROPERTIES AND MICELLIZATION OF SODIUM ALKYLSULPHATES IN THE PRESENCE OF LOW-MOLECULAR ALCOHOLS
Authors: Streltsova E. A. , Voliuvach O. V. , Tymchuk A. F.
Published: August 2024

The process of micellization of sodium alkyl sulfates (SAS : sodium decyl- (SDS) and dodecylsulfate (SDDS)) of formation in aqueous solution without or with alcohols including propanol-1, propanol-2 and butanol-1 and their adsorption behavior at air-liquid interface were investigated with both the tensiometry and the conductometry at 298 K. The effect of chain length of alcohol on micellar and interfacial properties were discussed. Some parameters including surface excess concentration (Γmax), minimum area per surfactant molecule (Smin) at air-liquid interface, degree of ionization of micelle, and standard free energy of adsorption and micellization, etc. are estimated. It was experimentally established that the introduction of 0.5-1.0 mol/dm3 of alcohols into surfactant solutions contributes to the process of micellar formation of SAS and increases the stability of the micellar phase, as evidenced by the observed synergistic effect on the critical micelle concentration (CMC). The addition of different alcohols changes the values of Γmax, Smin, CMC of SDS and SDDS and induces an increase in degree of ionization (β) of micelle relative to that in pure water. When alcohols are introduced into SDS and SDDS solutions, the degree of ionization of micelles at a constant length of the alkyl radical of surfactant moderately increases with increasing alcohol content in the solution and ranges from 0.50-0.73 and 0.38-0.75, respectively. Also, the effect of alcohol was discussed. The obtained thermodynamic parameters were used to confirm these behaviors of interfacial adsorption or micellization. An increase in chain length of alcohol promotes the micellization process. The CMC values decrease with increasing length of the alkyl radical of alcohols. Propanol-1, compared to propanol-2, somewhat reduces the value of SDS and SDDS CMC to a greater extent. Standard free energy of micellization ∆G0mic, also confirms the micellization behavior. Standard free energy of adsorption (∆G0адс) indicates that an increase in the chain length of alcohol in aqueous solution is favorable to the adsorption of SDS and SDDS at air-liquid interface. A comparison of the values of the standard free energy of adsorption and micelle formation in sodium alkyl sulfates – alcohols – water systems showed that adsorption is the most thermodynamically advantageous process in the studies systems, and the packing of surfactant “molecules” in micelles is less dense, compared to packing in a mixed adsorption layer.
The Role of Motivation in Mediating the Relationship of Emotional Intelligence in Leadership, Compensation, Work Environment to Performance
Authors: Widhiyasa I Putu Ardi , Sanica I Gede
Published: August 2024

This study aims to investigate the role of motivation as a mediating factor in the relationship between emotional intelligence in leadership, compensation, and work environment on employee performance at the Regional Secretariat of Badung Regency. A quantitative approach was utilized, involving 173 out of 304 civil servants as the sample. Data collection was conducted through questionnaires and analyzed using SEM-PLS with SmartPLS4 software. The findings revealed that emotional intelligence in leadership and compensation do not significantly influence employee motivation. Conversely, the work environment positively and significantly affects motivation. Emotional intelligence in leadership has a significant negative impact on employee performance, while compensation and work environment have a significant positive impact. Motivation also has a significant positive effect on employee performance. Furthermore, motivation does not mediate the influence of emotional intelligence in leadership and compensation on employee performance, but it does significantly mediate the relationship between work environment and employee performance. These findings underscore the importance of a conducive work environment in enhancing employee motivation and performance, providing valuable insights for human resource management in making informed decisions to improve employee performance in government institutions
SUITABILITY OF CONCRETE PRODUCED WITH HIGH CONTENTS OF CRUSHED WIND-TURBINE BLADE
Authors:   University of Burgos, Spain, Manso-Morato Javier , Hurtado-Alonso Nerea ,   University of Burgos, Spain, García-Llona Aratz ,   University of Lyon, France, Piñero Ignacio ,   Basque Research and Technology Alliance (BRTA), Spain, San-José José-Tomás ,   University of the Basque Country, Spain, Ortega-López Vanesa ,   University of Burgos, Spain
Published: August 2024

Some of the first-installed wind turbines will have to be replaced soon, as they are approaching the end of their life span. These wind-turbine blades must be recycled, so their suitability to be added into concrete mixes as fibers is studied. Thus, a less-polluting fiber-reinforced concrete can be achieved, maintaining its mechanical behavior. To recycle numerous wind-turbine blades at an adequate rate, large amounts of waste need to be added into concrete. This study aims to find out the suitability of adding high amounts of this waste material (0% vol., 5% vol., and 10% vol.). Testing yielded a slight decrease in fresh density and a higher occluded air content, yet largely maintaining its suitability for structural use according to the compressive strength. The results showed that concrete with a high content of crushed wind-turbine blade is suitable for structural use, being it an effective solution to said current sustainability problems.