bluuebunny/crossref_metadata_2025 huggingface dataset:
Networked Learning in Storyworlds: An Alternative Approach to Online Learning
Authors: Sánchez-Lozano Carlos , Cortés Catalina
Published: February 2019

Despite the advances in technology, passive information transfer remains at the core of online course design which results in lower student engagement and instructional effectiveness. This study focuses on the design, implementation and delivery of an online learning experience that combines the creation of a storyworld based on a ubiquitous computing framework, supported by the epistemic, set and social aspects of networked learning. Our aim is to analyse experience dynamics and learning strategies that emerge in a narrative-based scenario. The Community of Inquiry framework, which has been extensively validated, is being used to classify different interactions. This study is in progress but initial coding shows that response to the critical incident is significantly higher when compared to traditional forums. We have identified strong group cohesion and emotional expression. Further improvements in instructional strategies are suggested.
Fourth Graders’ Objectively Measured Week Long Physical Activity
Authors: Valtonen Juha , Kyhälä Anna-Liisa , Slotte Sari , Reunamo Jyrki
Published: February 2019

We explored 10–11 year-old children’s moderate to vigorous physical activity (MVPA) to describe how it is distributed within weekdays, weekend days, the segments of a schoolday and how it meets the global recommendation of ≥ 60 min daily MVPA. Participants were from two fourth classes (N = 33; 20 boys, 13 girls) in the city of Vantaa, capitol area of Finland. PA was measured using a Polar Active® (PAC) wrist-worn accelerometer. A diary supported the accelerometer data. Raw metabolic equivalent (MET) data from accelerometers were transmitted to computer, organized and uploaded to SPSS. We used MET-thresholds moderate PA (MPA) ≥ 3 6, vigorous (VPA) ≥ 6 and consequently moderate to vigorous PA (MVPA) ≥ 3. Average daily MVPA was 92 minutes. Differences between weekdays and weekend days existed, but they were at least partly caused by the weather. Global recommendation was met by 21%, more often by girls than boys. However, almost everyone met the recommendation ≥ 4 a week. In segments of the schoolday (lessons, long recesses, short recesses and lunch breaks) the children were physically quite active at 5, 12, 4 and 8 minutes, respectively. Hypothetically summed up, a schoolday accumulated 50 minutes MVPA. Boys accumulated quite systematically slightly more MVPA during schooldays and leisure time. Schooldays play an important role in children’s total MVPA and the current situation is decent. However, teacher educators, decision makers, school administration, principals, teachers and school staff should still aim at finding new ways of making schooldays even more physically active.
Outcomes for Pediatric Asthmatic Inpatients After Implementation of an Emergency Department Dexamethasone Treatment Protocol
Authors: Tyler Amy , Cotter Jillian M. , Moss Angela , Topoz Irina , Dempsey Amanda , Reese Jennifer , Szefler Stanley , Hoch Heather
Published: February 2019

OBJECTIVES:

Evidence supports using dexamethasone for mild-to-moderate asthma exacerbations in the emergency department, but the effectiveness of dexamethasone versus prednisone for asthmatic patients who are hospitalized is unclear. Our aim was to compare outcomes for inpatients before and after our emergency department’s adoption of dexamethasone for the treatment of acute asthma exacerbations.

METHODS:

In this single-center retrospective cohort study, we employed interrupted time series analyses to control for secular trends while evaluating our outcomes of length of stay, total inflation-adjusted hospital charges, and ICU transfer rates for patients admitted with asthma.

RESULTS:

Data were analyzed over 36 months (January 2014–April 2017) and included 1015 subjects (606 in the preprotocol change [pre-PC] group and 409 in the postprotocol change [post-PC] group). In the pre-PC group, prednisone only was used in 96% of subjects. In the post-PC group, prednisone only was used in 7% of subjects, dexamethasone in 65% of subjects, and a combination of the 2 steroids in 28% of subjects. Controlling for other variables in the interrupted time series model, we found no significant immediate differences between the pre-PC and post-PC periods for the outcomes of length of stay (P = .68), total charges (P = .66), and ICU transfers (P = .98). The rate of ICU transfers was stable pre-PC and increased by 10% (95% confidence interval: 2%–19%) per month (odds ratio = 1.10; 95% confidence interval: 1.02–1.19; P = .02) in the post-PC period.

CONCLUSIONS:

After dexamethasone replaced prednisone as the most commonly prescribed steroid type for inpatients with asthma at our institution, we found no immediate changes in outcomes for asthmatic patients who were hospitalized but an upward trend in ICU transfers.
Provider Knowledge, Attitudes, and Practices Regarding Bronchiolitis and Pneumonia Guidelines
Authors: Gold Jessica , Hametz Patricia , Sen Anita I. , Maykowski Philip , Leone Nicole , Lee Diana S. , Gagliardo Christina , Hymes Saul , Biller Rachel , Saiman Lisa
Published: February 2019

BACKGROUND AND OBJECTIVES:

Practice guidelines have been published for bronchiolitis and community-acquired pneumonia (CAP), but little is known about pediatricians’ knowledge of and attitudes toward these guidelines since their publication.

METHODS:

We surveyed pediatric providers at 6 children’s hospitals in the New York City area. Two vignettes, an infant with bronchiolitis and a child with CAP, were provided, and respondents were asked about management. Associations between respondent characteristics and their reported practices were examined using χ2 and Fisher’s exact tests. Associations between questions probing knowledge and attitude barriers relevant to guideline adherence and reported practices were examined using Cochran-Mantel-Haenszel relative risk estimates.

RESULTS:

Of 283 respondents, 58% were trainees; 57% of attending physician respondents had finished training within 10 years. Overall, 76% and 45% of respondents reported they had read the bronchiolitis and CAP guidelines, respectively. For the bronchiolitis vignette, 40% reported ordering a chest radiograph (CXR), and 38% prescribed bronchodilators (neither recommended). For the CAP vignette, 38% prescribed ceftriaxone (not recommended). Study site, level of training, and practice locations were associated with nonrecommended practices. Site-adjusted knowledge and attitude barriers were used to identify that those who agreed CXRs were useful in managing bronchiolitis were more likely to order CXRs, and those who felt bronchodilators shortened length of stay were more likely to prescribe them. Concerns about ampicillin resistance and lack of confidence using local susceptibility patterns to guide prescribing were associated with ordering ceftriaxone.

CONCLUSIONS:

Provider-level factors and knowledge gaps were associated with ordering nonrecommended treatments for bronchiolitis and CAP.
Valoración económica de una mejora en las condiciones laborales de los recolectores informales de material reciclable en Guaymallén, Argentina
Authors: Farreras Verónica , Huanca Gisel
Published: February 2019

Bajo la modalidad de estudio de caso, se infiere el valor económico para una mejora en las condiciones laborales de los recolectores informales de material reciclable en Guaymallén, Argentina. Mediante el método de los experimentos de elección discreta, se estimó la disposición a pagar de un conjunto de ciudadanos para la implementación de políticas que podrían mitigar simultáneamente los problemas de salud y lesiones causadas por el tránsito que impactan la calidad de vida de los recolectores informales. Este análisis puede resultar de especial interés para la formulación de políticas públicas que pretenden generar una gestión eficiente de los residuos sólidos urbanos.
Evaluación de la gestión de prestaciones económicas en servicios sociales comunitarios: el caso de Andalucía (España)
Authors: Peláez Quero Encarna , Pastor Seller Enrique
Published: February 2019

La Ley 9/2016 del 27 de diciembre, de Servicios Sociales de Andalucía, ha conformado un nuevo statu quo en la protección social de la comunidad autónoma. Se plantea su estudio en dos fases concatenadas, en las que se pretende comprobar si la regulación y la gestión en los Servicios Sociales Comunitarios de la provincia de Almería, de prestaciones económicas para la cobertura de necesidades básicas de alimentación y alojamiento, respetan el espíritu de la Ley aprobada recientemente. En la primera fase, se ha diseñado un sistema de análisis de las prestaciones y, en la segunda, se aplica ese sistema a las prestaciones previamente determinadas.
Trans fatty acids in food – current legal regulations as protections for consumers and food manufacturers
Authors: Zuchowska-Grzywacz M. , Kowalska M.
Published: February 2019

It was the goal of this paper to introduce selected regulatory models concerning the legal status of trans fatty acids in connection with the consumer’s position and to propose some de lege ferenda conclusions.

Legislation, treatises, periodicals, and bulletins have been analysed. Information from portals associated with the European Union and posted on official websites of organizations like the WHO is presented.

As comprehensive descriptions of individual states’ approaches to trans fats’ presence in the human diet are not available, an attempt was undertaken to obtain as broad a range of positions as possible, of states willing to take part in the study. Alongside research based on responses from Health Ministries of the EU member countries and three states from outside the EU, its conclusions, observable trends, and solutions proposed to minimize content of trans fatty acids are an essential part of this study.

Analysis of legislation and positions on trans fatty acids presence in food submitted by the states demonstrated the need for a consistent, overall regulation of the issue. The authors relied on the information generated to outline such solutions.
New southernmost record of the European Brook Lamprey, Lampetra planeri (Bloch, 1784) (Agnatha, Petromyzontidae)
Authors: Sperone Emilio , Filice Mariacristina , Giglio Gianni , Leonetti Francesco L. , Tripepi Sandro , Imbrogno Sandra
Published: February 2019

We report the occurrence of the European Brook Lamprey, Lampetra planeri (Bloch, 1784), in the Lao river in the Calabria region (southern Italy). This record extends the species’ known distribution limit southwards. Information regarding some morphometric and ecological data are provided and discussed.
Preaching as Internal Interreligious Dialogue: A Harvard Case Study
Authors: Malmström Hans , Schnasa Jacobsen David
Published: February 2019

This paper explores the overlapping space between an internal conception of interreligious dialogue and models of conversational preaching and homiletical theology which embrace mutual critical-correlational theological method. At the heart of the paper is a close reading of a sermon focusing on John 5:31–47—preaching much influenced by interreligious hermeneutics. The analysis shows how preaching effectively may address some fundamental principles of interreligious dialogue, for example by offering space for open-minded, respectful, and attentive listening and learning from the religious other, or by encouraging curiosity as well as deep reflection on Christian gospel in the light of gospel resonant of voices from other religious traditions. In the concluding discussion, the implications of this research for the rhetoric of conversational preaching practice are highlighted, and further homiletical-theological reflection on the relationship between preaching and interreligious dialogue is encouraged, not only because it is possible but because it is desirable for Christian preaching and homiletics in particular.
Silencio, subjetividad y ficción en los testimonios de mujeres sobrevivientes
Authors: Davidovich Karin
Published: February 2019

Este artículo analiza la producción testimonial de ex detenidas desaparecidas de la última dictadura militar en Argentina (1978-1983), poniendo de relieve la presencia de los silencios existentes en estos relatos. Los relatos testimoniales de las sobrevivientes Graciela Fainstein, Graciela Lo Prete, Nora Strejilevich y Alicia Partnoy, entre otros, ponen en evidencia las dificultades a las que se enfrenta todo sobreviviente del horror, en tanto debe narrar aquello que dada su naturaleza traumática desafía cualquier tipo de representación. Frente a esta dificultad, las sobrevivientes buscan en la articulación entre lo dicho y lo no dicho, entre la palabra y el silencio, desafiar las limitaciones del lenguaje frente al horror, construyendo un relato que incorpora lo difuso y llama a la imaginación. Estos testimonios presentan rasgos particulares que los diferencian de los testimonios masculinos, tales como la posición subjetiva desde la cual las narradoras cuentan su historia, la multiplicidad de perspectivas, el quiebre de una narración lineal dentro de estos testimonios, así como también el uso del silencio como herramienta a través de la cual comunicar el horror y cuestionar las limitaciones del lenguaje. Este tipo de testimonio se convierte así en documento de la experiencia traumática, que dada su naturaleza, no puede sino estar constituido por interrupciones, huecos y silencios.
(Dis) locating the I of the Yo in Julia Álvarez's Yo and Mario Vargas Llosa's La fiesta del Chivo
Authors: Luis William
Published: February 2019

N/A
The Life and Times of Michael Young: from the new sociology of education to socialist realism in English schooling
Authors: Morgan John
Published: February 2019

This article defends Michael Young from accusations of simple revisionism, and reasserts the need for the socialist left to debate the nature and importance of school knowledge and of subject disciplines.
Ending Selection in the Schools of Guernsey
Authors: Sherbourne Peter
Published: February 2019

This article gives an insider's account of the campaign, ultimately successful, to end the system of educational selection at age 11 on the island of Guernsey.
'Nothing New and Shiny.' My Experience with Learning without Limits: a teacher's journey
Authors: Woods Katie
Published: February 2019

This article offers one teacher's thoughts about how the experience of having to teach students who had been labelled and grouped by 'ability' unsettled her practice. Such 'ability' thinking runs counter to her beliefs as a teacher. The article sheds light on ways in which practice
can be re-fashioned in the light of principles associated with Learning without Limits approaches.
A Cost-Effectiveness Analysis of Nivolumab and Ipilimumab Versus Sunitinib in First-Line Intermediate- to Poor-Risk Advanced Renal Cell Carcinoma
Authors: Reinhorn Daniel , Sarfaty Michal , Leshno Moshe , Moore Assaf , Neiman Victoria , Rosenbaum Eli , Goldstein Daniel A.
Published: February 2019

Background

The treatment paradigm of advanced renal cell carcinoma (RCC) has changed rapidly in recent years. In first-line treatment of intermediate- to poor-risk patients, the CheckMate 214 study demonstrated a significant survival advantage for nivolumab and ipilimumab versus sunitinib. The high cost of combined immune-modulating agents warrants an understanding of the combination's value by considering both efficacy and cost. The objective of this study was to estimate the cost-effectiveness of nivolumab and ipilimumab compared with sunitinib for first-line treatment of intermediate- to poor-risk advanced RCC from the U.S. payer perspective.

Materials and Methods

A Markov model was developed to compare the costs and effectiveness of nivolumab and ipilimumab with those of sunitinib in the first-line treatment of intermediate- to poor-risk advanced RCC. Health outcomes were measured in life-years and quality-adjusted life-years (QALYs). Drug costs were based on Medicare reimbursement rates in 2017. We extrapolated survival beyond the trial closure using Weibull distribution. Model robustness was addressed in univariable and probabilistic sensitivity analyses.

Results

The total mean cost per-patient of nivolumab and ipilimumab versus sunitinib was $292,308 and $169,287, respectfully. Nivolumab and ipilimumab generated a gain of 0.978 QALYs over sunitinib. The incremental cost-effectiveness ratio (ICER) for nivolumab and ipilimumab was $125,739/QALY versus sunitinib.

Conclusion

Our analysis established that the base case ICER in the model for nivolumab and ipilimumab versus sunitinib is below what some would consider the upper limit of the theoretical willingness-to-pay threshold in the U.S. ($150,000/QALY) and is thus estimated to be cost-effective.

Implications for Practice

This article assessed the cost-effectiveness of nivolumab and ipilimumab versus sunitinib for treatment of patients with intermediate- to poor-risk metastatic kidney cancer, from the U.S. payer perspective. It would cost $125,739 to gain 1 quality-adjusted life-year with nivolumab and ipilimumab versus sunitinib in these patients.
Prevention of pregnancy loss in women with circulation of non-conventional antiphospholipid autoantibodies
Authors: Kornyushina Ekaterina A. , Chepanov Sergey V. , Selkov Sergey A. , Dadayeva Dzhamilya G. , Shakhaliyev Rustam A. , Chudotvorov Kirill N. , Nemstsveridze Nadezhda N.
Published: February 2019

Hypothesis/aims of study. Patients with a history of pregnancy complications that meet the clinical criteria of antiphospholipid syndrome (APS), with circulation of autoantibodies not related to the laboratory criteria for APS, present difficulties in choosing a method for preventing recurrent complications. The aim of this study was to determine the frequency of autoantibodies in women with severe obstetric complications and habitual miscarriage and to evaluate the effectiveness of therapy used in APS for the prevention of recurrent reproductive losses in women with non-criteria autoantibodies.

Study design, materials and methods. 358 women with a history of APS clinical criteria or two pregnancy losses up to 10 weeks were examined. Anti-beta2-glycoprotein I and anti-cardiolipin (IgG/IgM) antibodies, as well as non-conventional autoantibodies for phosphatidylinositol, phosphatidylserine, phosphatidyl acid, annexin V, and prothrombin were determined in serum, with lupus anticoagulant test performed. In 39 women with clinical criteria for APS and circulating anti-annexin V or prothrombin antibodies during pregnancy, enoxaparin sodium was used (in 100% of the cases) in combination with acetylsalicylic acid (ASA) at a dose of 50-100 mg per day (in 69.2% of the cases).

Results. The frequency of all types of autoantibodies was 38.8%. Non-conventional antibodies were detected in 17.6% of the cases (isolated circulation in 11.5% of the cases); with anti-annexin V antibodies (73.0%) prevailed among them. In 39 patients with non-criteria antibodies, after the use of a prophylactic dose of enoxaparin sodium and ASA, live births were the outcome of pregnancy in 84.6% of the cases.

Conclusion. Testing for non-conventional autoantibodies may be appropriate in patients with only APS clinical criteria. Standard treatment of APS prescribed for this group of patients led to a significant increase in the frequency of live births. Further large studies are needed to evaluate the efficacy of medical prophylaxis of adverse pregnancy outcomes in women with non-criteria obstetric ABS.
Vitamin D deficiency as a factor in reducing bone mineral density after childbirth
Authors: Novikova Tatyana V. , Zazerskaya Irina E. , Kuznetsova Lyubov V. , Bart Viktor A.
Published: February 2019

Hypothesis/aims of study. Physiological pregnancy is not a reliable risk factor for reduced bone mineral density (BMD). The causes affecting BMD in reproductive age, such as smoking, heredity, low physical activity, low body mass index, unbalanced diet, ovarian dysfunction, and vitamin D deficiency are studied. The aim of this study was to assess the contribution of vitamin D deficiency and insufficiency to the development of osteopenia after childbirth.

Study design, materials and methods. This is a cohort study conducted in V.A. Almazov National Medical Research Center, Saint Petersburg, Russia in the period from October 2013 to November 2014. We examined 86 puerperas on days 3–5 after delivery. The age of women ranged from 20 to 35 years. Patients were surveyed using the questionnaire on the main risk factors for osteoporosis. The method of dual energy X-ray absorptiometry was used to evaluate BMD in the central and peripheral skeleton. Serum levels of 25-hydroxycalciferol (25(OH)D) and parathyroid hormone were determined in all pregnant women.

Results. According to the results of Х-ray osteodensitometry, normal BMD was detected in 45% (n = 38) of puerperas (comparison group), with reduced BMD revealed in 55% (n = 48) of puerperas (main group). The main group was divided into subgroups: osteopenia in the distal forearm was detected in 27 (56%) puerperas, in the proximal femur in 7 (16%) puerperas, and in the lumbar spine in 14 (28%) puerperas. 58-78% of patients showed vitamin D deficiency and insufficiency. In the group with osteopenia, vitamin D deficiency prevails, reaching 78% in women with osteopenia in the forearm, while in the group with normal BMD, vitamin D deficiency predominates in 70% of patients. The mean value of 25(OH)D in serum in the group with osteopenia and that in the group with normal BMD differ 1.5 times. The level of 25(OH)D in postpartum women with osteopenia in the forearm is two times lower, when compared to the group with normal BMD, parathyroid hormone being within reference values. In the group with osteopenia in the lumbar spine, opsooligomenorrhea is more common (p < 0.05), while in the group with osteopenia in the proximal forearm, a possible significant factor was revealed to be preeclampsia (p < 0.05).

Conclusion. Osteopenia after childbirth is found in 55% of patients. In 56% of cases, osteopenia occurs in the distal forearm. Vitamin D deficiency is a significant factor in the reduction of BMD in the distal forearm and lumbar spine. At a level of 25 (OH) D < 20 ng/ml, the risk of developing osteopenia increases by 56%.
President's Address 2015: Gatekeeping for the Future
Authors: Copeland Sam
Published: February 2019

Grade inflation in baccalaureate social work programs, its causes, and how it affects the future of social work and students are discussed.
Thrombosis risk factors and gene mutations in young age patients with acute coronary syndrome
Authors: Ponomarenko I. V. , Sukmanova I. A.
Published: February 2019

Goal of research. Study the role of thrombosis risk factors and polymorphisms in genes in young age patients with acute coronary syndrome (ACS).

Materials and methods. Te study included 299 patients of age 25 to 44 years old with ACS were treated from 2012 to 2017 at the department of myocardial infarction 1st KGBUZ Altay regional cardiological clinic. Te middle age of patients with ACS was 40.3 ± 0.2 years. Te control group included of 53 apparently healthy volunteers aged from 25 to 44 years old, the average age those patients was 39.94 ± 0.79 years. Also, those patients hadn’t any comorbid conditions. Te control group hadn’t any datas of ischemic heart disease by the results of exercise tolerance tests. All patients had standard clinical, anamnestic, biochemical tests, lipid profle, fasting plasma glucose, electrocardiogram, echocardiography and coronaroangiography, also they were determined growth and weight with body-weight index. 116 patients from the ACS group and 53 patients fromthe control group had screening of polymerase chain reaction for determine polymorphism of the FII genes G20210-A, FV G1691-A, and MTHFR C677-T.

Results. We identifed the most signifcant sets of risk factors associated with ACS in young age patients based on our multifactorial statistical analysis with binary logistic regression. Tis combination of risk factors was: increased levels of low-density lipoproteins, decreased levels of high-density lipoproteins, smoking, existence of MTHFR homozygous polymorphism, heredity in combination with smoking, FV homozygote, MTHFR homozygote, smoking with MTHFR-homozygote.

Conclusion. Te ability predicting the risk of developing cardiovascular disease in young people based on traditional risk factors, partly modifable, as well as the researching of "new" risk factors, opens up new opportunities for developing a clinical approach of treating young patients with high risk of ACS.
Arturo Valencia Islas, El descarrilamiento de un sueño: historia de los Ferrocarriles Nacionales de México, 1919-1949, México, Centro Nacional para la Preservación del Patrimonio Ferrocarrilero/El Colegio de México, 2017, 348 pp.
Authors: Beltrán Juárez Jorge Fernando
Published: February 2019

No contiene resumen.
Feature Extraction for Retina Image Based on Difference Approaches
Authors: Erwin Erwin , Saparudin Saparudin , Putri Arum Cantika , Hidayat Hidayat , Hariyani Fifi
Published: February 2019

Automatic disease diagnosis using biometric images is a difficult job due to image distortion, such as the presence of artifacts, less or excessive light, narrow vessel visibility and differences in inter-camera variability that affect the performance of an approaches. Almost all extraction methods in the blood vessels in the retina produce the main part of the vessel with no patalogical environment. However, an important problem for this method is that extraction errors occur if they are too focused on the thin vessels, the wide vessels will be more detectable and also artificial vessels that may appear a lot. In addition, when focusing on a wide vessel, the extraction of thin vessels tends to disappear and is low. Based on our research, different treatments are needed to extract thin vessels and wide vessels both visually and in contrast. This study aims to adopt feature extraction strategies with different techniques. The method proposed in segmentation and extraction with three different approaches, namely the pattern of shape, color, and texture. Testing segmentation and feature extraction using STARE datasets with five classes of diseases namely Choroidal Neovascularization, Branch Retinal Vein Occlusion, Histoplasmosis, Myelinated Nerve Fibers, and Coats. Image enhancement on Myelinated Nerve disease Fiber is the best result from the image of other diseases with the highest value of PSNR of 35.4933 dB and the lowest MSE of 0.0003 means that the technique is able to repair objects well. The main significance of this work is to increase the quality of segmentation results by applying the Otsu method. Testing of segmentation results shows improvements with the proposed method compared to other methods. Furthermore, the application of different feature extraction methods will get information on disease classification features based on patterns of suitable shapes, colors, and textures.
Early-stage coronary artery atherosclerosis patients in 4-year follow-up
Authors: Dąbek Józefa , Majewski Michał , Bałys Mariusz , Gąsior Zbigniew
Published: February 2019

Wstęp

Choroby układu krążenia, powodowane głównie miażdżycą i jej powikłaniami, są najczęstszą przyczyną chorobowości i śmiertelności na świecie. Miażdżyca rozwija się już we wczesnym wieku dziecięcym, a u około 50% młodych osób występują cechy miażdżycy tętnic wieńcowych. W związku z tym podejmuje się wiele działań zmierzających do wczesnego jej wykrywania i identyfikacji osób o podwyższonym ryzyku powikłań sercowo-naczyniowych, u których wdrożenie zasad prewencji może zapobiegać progresji choroby oraz rozwojowi powikłań. Subkliniczna miażdżyca to wczesny etap rozwoju choroby z obecnością niewielkich zmian w ścianie tętnic wieńcowych. Wykazano związek wczesnej miażdżycy ze zwiększonym ryzykiem choroby wieńcowej i występowaniem powikłań w postaci zgonów z przyczyn wieńcowych, zawałów serca niezakończonych zgonem oraz objawowej dławicy piersiowej. Celem pracy była obserwacja odległa osób z wczesną miażdżycą tętnic wieńcowych.

Materiał i metody

Z pierwotnej grupy 45 chorych (100%) we wczesnym etapie zaawansowania miażdżycy tętnic wieńcowych – obejmującej pacjentów, u których w koronarografii uwidoczniono prawidłowy obraz tętnic wieńcowych lub jedynie drobne zmiany przyścienne, natomiast w 64-rzędowej tomografii komputerowej wskaźnik uwapnienia tętnic wieńcowych był dodatni (CACS powyżej 0) – obserwacji odległej poddano 29 osób (64,5%).

Wyniki

W analizowanej grupie 29 chorych w 48-miesięcznej obserwacji stwierdzono dobre rokowanie ogólne. Nie występowały zgony z przyczyn sercowo-naczyniowych ani poważne zdarzenia sercowo-naczyniowe niezakończone zgonem. Ponadto chorzy dobrze współpracowali w zakresie procesu terapeutycznego, stosowali się do zaleceń oraz kontrolowali choroby współistniejące. U większości badanych doszło do poprawy w zakresie objawowości niedokrwienia mięśnia sercowego.

Wnioski

Uzyskane dane pozwalają uznać subpopulację pacjentów we wczesnym etapie zaawansowania miażdżycy tętnic wieńcowych za obarczoną pośrednim ryzykiem sercowo-naczyniowym.
Mekanisme Infeksi Vibrio Pada Reseptor Ikan Kerapu Tikus Cromileptes altivelis [The Mechanism Of Vibrio Infection To Grouper Reseptor Cromileptes altivelis]
Authors: Yanuhar Uun
Published: February 2019

Abstract One of the most favourite fish that farmer fish cultivated because its high economic value was gouper (C. altivelis). The obstacle in cultivation system was caused by Vibrio algynolitycus. Vibrio angullarum, Vibrio parahaemolyticus. Vibrio harveyi infection. Many deseases that attacked to the grouper was caused by the role of pathogen specific as a ligan and its reseptor. The aim of these study was to improve and to know the role of reseptor in vibriosis mechanism with tested spesific reseptor protein of grouper Cromileptes altivelis. These study used experimental and descriptive methode with identified of grouper reseptor, Hemaglutinin test and observation use electron microscope. These study result showed that reseptor protein of C. altivelis was found in its eyes. These showed spesivity and reactivity to the vibriosis specific epitop.
Pengaruh Konsentrasi Kadmium Terhadap Perubahan warna Dan Persentase Jenis Kelamin Jantan Anakan Daphnia magna [Influences Concentration Of Cadmium To Colour Change And Male Sex Percentage Neonates Daphnia magna]
Authors: Kusdarwati Rahayu , Hermawati W Alfi , Sigit Setyawati , Mubarak A. Shofy
Published: February 2019

Abstract Cadmium is one of dangerous heavy metal and it can cause water pollution. As an alternative early warning toward heavy metal in water, Daphnia magna can be used as biology indicator water pollution that caused by heavy metal. Daphnia magna is organism that ussualy used for bioassay in many progressing countries, because that organism have important role in freshwater ecology, short life cycle about 3 weeks and sensitive toward chemical environment. Grade of toxicity heavy metal can measured with lethal and sub lethal parameter. In Daphnia magna, sub lethal parameter that can be observe are colour changes and male sex percentage neonates. The purpose of this research was to know the colour changes and male sex percentage neonates Daphnia magna in different concentration of cadmium. Target of this research is to gets information about level colour changes and male sex percentage neonates Daphnia magna in different concentration of cadmium. The main parameter was colour changes and male sex percentage neonates and the secondary parameters were water quality (temperature, pH, dissolved oxygen and NH3) The result of research of giving different cadmium concentration to the adult female Daphnia magna not showing significant influence, nevertheless it is showing significant influence toward male sex percentage neonates Daphnia magna. The treatment with cadmium concentration 0,0004 mg/l produce 100% male neonates Daphnia magna. Water quality during research were in optimal conditions to support Daphnia magna life, those are temperature 26°C, pH range from 8,0 – 8,2 and dissolve oxygen (DO) range from 8,5 – 9,0 mg/l and ammonia 0 – 0,03 mg/l.
Pengaruh Pemberian Pakan Alami Dan Pakan Buatan Terhadap Pertumbuhan Benih Ikan Betutu (Oxyeleotris marmorata bleeker)Pengaruh Pemberian Pakan Alami Dan Pakan Buatan Terhadap Pertumbuhan Benih Ikan Betutu (Oxyeleotris marmorata bleeker) [The Influence Of Giving Natural Feed And Make Feed To Growth Fingerlings Of Betutu (Oxyeleotris marmorata bleeker)]
Authors: Arief Muhammad , Triasih Irmaya , Paramita Lokapirnasari Widya
Published: February 2019

Abstract The growth of betutu classified slow, so do efforts in order that growth of betutu which protected optimal by choosing the exact food combination. This research is purpose to know the growth fingerlings of betutu. This research using complete random program giving 3 repeated by the way of treating P1 (food 100% pelet), P2 (food 100% Daphnia spp.), P3 (food 100% Tubifex sp.), P4 (food 100% Anadara granosa), P5 (food combination 50% pelet and 50% Daphnia spp.), P6 (food combination 50% pelet and 50% Tubifex sp.), P7 (food combination 50% Anadara granosa and 50% Daphnia spp.), P8 (food combination 50% Anadara granosa and 50% Tubifex sp.). Main test parameter checked on this research is growth (accretion weight), growth rate, specific growth rate, and absolute body length growth, while supporting test parameter is water quality. Data of growth analysis using ANAVA (varian analysis) and if there is the influence the way of treating so continued with Test of Multiple Gap Duncan by trusty degree 95%. The result of research show the growth (accretion weight), growth rate, specific growth rate and the best absolute body length growth on the way of treating P6 which not different with the way of treating P3 and P8.
Respon Daya Cerna dan Respirasi Benih Ikan Mas (Cyprinus carpio) Pasca Transportasi Dengan Menggunakan Daun Bandotan (Ageratum conyzoides) Sebagai Bahan Antimetabolik [Digestibility Response and Respiration Post Transportation With Bandotan (Ageratum conyzoides) Leaf As Antimetabolic Of Common Carp (Cyprinus carpio) Fry ]
Authors: Sulmartini Laksmi , Chotimah Dewi Nurul , Tjahjaningsih Wahju , V. Thomas , Widiyatno Widiyatno , Triastuti Juni
Published: February 2019

Abstract Common carp (Cyprinus carpio) is fish with high metabolism during transportation caused fish stress and could due to impare condition of fry fish and also lead to mortality post transpotation. As effort to minimize high metabolism during transportation was use bandotan leaf as nature antimetabolic so that we need to know how far bandotan effect to condition by digestibility and respiration of common carp fry during post transportation critical periode. The aim of this study was to know condition of common carp fry for 3 days post transportation by digestibility and respiration with bandotan leaf. This study used Complete Random Design. The treatment were A (water 0,5 l) B (bandotan leaf water dose 3,25 g/l) dan C (bandotan leaf water dose 4,5 g/l), each treatment with 6 replications. Primary parameter were digestibility (%) and respiration (time). Secondary parameter were mortality (%), and water quality (disolve oxygen, temperature, ammonia and pH). The result show that bandotan leaf was significantly influenced (p<0,05) to digestibility common carp (Cyprinus carpio) fry at 48 hour post transportion. Bandotan leaf significantly influenced (p<0,05) to respiration common carp (Cyprinus carpio) fry for 72 hour post transportion. Dose of bandotan leaf was 4,5 g/l could used to common carp fry transportation without mortality that was caused by change of digestibility and respiration response.
Pemberian Tepung Limbah Udang yang Difermentasi dalam Ransum Pakan Buatan Terhadap Laju Pertumbuhan, Rasio Konversi Pakan Dan Kelangsungan Hidup Benih Ikan Nila (Oreochromis niloticus) [The Given Fermentation The Prawn Waste Flour In Artificial Feed On Growth, Feed Convertion Ratio and Survival Rate Of Black Nile Tilapia (Oreochromis niloticus) ]
Authors: Agustono Agustono , Hadi Muhammad , Cahyoko Yudi
Published: February 2019

AbstractThe aim of this research was to find out optimum percentage of given fermentation the prawn waste flour in artificial feed on growth of black nile tilapia. The treatment of this research was giving fermentation the prawn waste flour in artificial feed i.e. 0%, 2,5%, 5%, 7,5%, 10%. Each treatment was repeated 4 times. Feed compositon was made of isoprotein. Fishes weight were about 6.1 – 6.8 g. Fishes were cultured with stocking rate 3 fish per 20 liter water and the fishes were reared for 40 days. Feed amount that consumed by fishes was measured every day to calculate feed conversion ratio. The calculation of fishes amount was done in beginning and end of research to count survival rate of fishes. Water quality was measured on beginning, middle and end of research. The design of this research was Completely Randomized Design. Data analysis used Analysis of Variance (ANOVA) to know the effect of the treatment and that difference among the treatment used Duncan's Multiple Range Test (DMRT). The result of the research showed that the highest growrth rate were attained on feed containing 10% of fermented prawn waste flour. The best feed convertion ratio were attained on feed containing 10% of fermented prawn waste flour.
Pengaruh Prosentase Pemberian Pakan Terhadap Kelangsungan Hidup Dan Laju Pertumbuhan Udang Vannamei (Litopenaeus vannamei) [The Effect Of Feed To Survival And Growth Rate Of Vannamei Shrimp (Litopenaeus vannamei) ]
Authors: Nuhman Nuhman
Published: February 2019

AbstractFeed is an important factor in the culture of vannamei shrimp. The optimum feed have clone to prevent underfeeding or overfeeding, whereas the amount of feed must have adjust with shrimp biomass. The aim this research is to know the percentage of optimum feed from vannamei shrimp. The method is experimental research with Complete Random Design, and the result showed that difference of percentage of feed is not significantly for daily growth of vannamei shrimp. The amount of feed as mush as 40 % of biomass weight/day showed the best daily growth (9.86 %).
Pengaruh Lama Penyinaran Terhadap Pertumbuhan dan Klorofil A Gracilaria verrucosa Pada Sistem Budidaya Indoor
[The Influence Of Radiation Time Of Growth and Chlorophyll A Gracilaria verrucosa In Indoor Cultivation System]
Authors: Alamsjah Moch. Amin , Ayuningtiaz Nurines Oktavia , Subekti Sri
Published: February 2019

AbstractGracilaria cultivation is basically in need of lighting for photosynthesis process which will be a great effect on growth. The use of fluorescent (FL) as a replacement for the sun light is used for fluorescent lamps produce white light, except that fluorescent lights do not increase the room temperature drastically culture (temperature stable) and the intensity of light produced in the culture room suitable for the growth of shoots Gracilaria verrucosa. In addition to light intensity, while irradiation also affects the growth of cultured algae. Long exposures are generally set according to the needs of algae in natural conditions. In the process of photosynthesis is need a light and dark reaction. Light reaction occurs in the conversion of light energy into chemical energy and dark reactions occur for the formation of glucose that used for catabolism system. This study aims to determine the best long exposures of the different long exposures which can affect the growth and the amount of chlorophyll a of G. verrucosa. The methods is an experimental that used Complete Random Design (RAL) as the experimental design. The treatment used is different irradiation time, the treatment A (long irradiation for 24 hours, control), treatment B (irradiation time 12 hours light: 12 hours dark), treatment C (irradiation time 8 hours light: 16 hours dark) and D treatment (irradiation time 16 hours light: 8 hours dark) of each treatment is repeated five times. The main parameters were observed daily growth rate (%/day) and the amount of chlorophyll a (µg/ml) of G. verrucosa. Supporting the observed parameters are pH, temperature (ºC) and salinity (%o) The analysis data is using of variants analysis (ANOVA), if there is a difference data followed by Duncan's Multiple Range Test to determine the best treatment. The results showed that different irradiation time take a real effect (P <0.05) on the growth and the amount of chlorophyll a G. verrucosa. Daily weight growth rate of the highest average found in treatment D (irradiation time 16hour light: 8-hours dark) of 0.62%/day, and the lowest in treatment A (24-hour long light irradiation) of 0.23%/day. The highest number of chlorophyll a average at the end of the study are in treatment D (irradiation time 16-hours light : 8 hours dark) of 0.0068 µg/ml and the lowest in treatment A (24-hour long light irradiation) of 0.0048 µg/ml. The increasing daily growth rate of G. verrucosa can used of the irradiation time 16-hours light : 8-hours dark.
Manajemen Pembesaran Kerapu Tikus (Cromileptes altivelis) di Balai Besar Pengembangan Budidaya Air Payau (Bbpbap) Jepara Jawa Tengah
[Nursery Management Of Grouper (Cromileptes altivelis) In Development Brackish Water Center Jepara Center Java]
Authors: Tjahjaningsih Wahyu , Septinawati Atmirah
Published: February 2019

AbstractThe mouse grouper is variance of grouper that have high economic value because it have high sale value so that it will increase income of aquaculturist. The right management of grouper nursery would increase production to supplied the marketing demand. The aims of this case study were to know how nursery management of grouper and factors that influence in grouper nursery in BBPBAP Jepara, was held on 28 July until 28 August 2005. Method used were descriptive method with collection of primary data and secondary data. Data was taken by observation, interview, active participation and literature study. Nursery of grouper fish carried out by BBPBAP Jepara under Departement of Marine and Fisheries. Source of fry were obtain from hatchery division in BBPBAP. Marine water were obtain from the sea, while fresh water were obtain from well. Fish feeding were use trash fish which were cut to suitable with mouth gapes of fish as much 90 gram, twice a day were morning and afternoon. In the fish nursery were not find disease that attack. The marketing area of grouper were Semarang, Jakarta, Surabaya, and local consumer.
Perubahan Patologi Kulit Ikan Gurami (Osphronemu gouramy) Akibat Infestasi Lernaea cyprinacea Pada Derajat Infestasi Yang Berbeda
[The Pathology Alteration Of Gouramy (Osphronemus gouramy) Integument Infested By Lernaea cyprinacea At Different Degress Of Infestation]
Authors: Mahasri Gunanti , Sari Putri Desi Wulan , Koesdarto Setiawan
Published: February 2019

Abstract The development of fish consumption in Indonesia was promising increasingly and growing very rapidly. One of the priority commodities in the development of aquaculture subsector was the gourami (Osphronemus gouramy). Many factors must be faced in the cultivation of gouramy, including the problem of fish diseases caused by Lernaea cyprinacea. The aim of this research is to find out the description of anatomic pathology and histopathology of gouramy which infested by L. cyprinacea at different degrees of infestation. This research uses descriptive method. The research showed that the gouramy integument which infested by L. cyprinacea at low, moderate and heavy infestation cause moderate until heavy defect with 2.48; 2.42 and 2.32 in reaverage scoring. Hence, accordance with pathological anatomy, L. cyprinacea infestation caused necrotic nodules, lesion which covered by exudate and haemorrhage. While the histopathology of the integument changes found were inflammatory cell infiltration, congestion and haemorrhage in the low, moderate and heavy infestation.
Obyek Kesukaan untuk Penempelan Telur (Oviposisi) Ektoparasit Argulus japonicus
[ Preference Of Oviposition Object Of Ectoparasite Argulus japonicus]
Authors: Kismiyati Kismiyati , Iskhaq Nur Maulana , Triastuti Juni
Published: February 2019

Abstract A. japonicus is ectoparasite that attack only freshwater fish. The fish that was attacked by A. japonicus look skinny, always rub their body and appear some red spot that will manifest for second infection. Prevent and controll of A. japonicus, were used drug or chemical materials like insecticide. This compound can damage the environment and destroy surround ecosystem. Precisely metode to controll A. japonicus was focused for egg stage. The female habits of A. japonicus always lay her eggs (oviposition) on the surface object that surround on they habitat. The research using completely randomized design (CRD). The treatment on this research use 4 oviposition object like rock, wood, plants and PVC pipe. A rock that representative a hard and rough surface. Wood that representative rather solid state and irregular surface, plants with hard surface and representative a life organism (using Echinodorus palaefolius with wide and hard surface leaf), also PVC object that representative a hard and smooth surface. For comparator treatment, all oviposition object was collected in one treatment. All treatment were replicated at four times. Object was placed on bottom aquarium for use as oviposition object, to know preference of oviposition object by oviposition periode and totally eggs produced. ANOVA (analysis of variance) and Tukey-HSD range test were used to analyze data. Results showed that significant effect (p <0,05) on oviposition time and total eggs. The longest oviposition time and the higest eggs total was made by rock and pipe. The fastest oviposition time and the lowest eggs total was made by plants. Water quality during the study in optimum condition for A. japonicus and goldfish , temperature ranges from 26-28 0C, pH 7 and dissolved oxygen (DO) ranged at 5 mg/L.
Pengaruh Pemberian Pakan Buatan, Pakan Alami, dan Kombinasinya terhadap Pertumbuhan, Rasio Konservasi Pakan dan Tingkat Kelulushidupan Ikan Sidat (Anguilla bicolor)
[Effect Of Artificial Feed, Natural Feed And Combination Between Them To Growth Rate, Food Convertion Ratio And Survival Rate Of Indonesian Shortfin Eel (Anguilla bicolor) ]
Authors: Arief Muhammad , Pertiwi Dwi Kukuh , Cahyoko Yudi
Published: February 2019

Abstract Indonesian shortfin eel (Anguilla bicolor) is one of kind of fish sold in the International markets especially for Japan and Korea, so this fish has the potential as an export commodity. Indonesian shortfin eel has a high nutrient content. Indonesian shortfin eel reached the size of concumption when it is weighted 120-500 grams. The purpose of this research was to know the effect of artifial feed, natural feed and combination between them to growth rate, food convertion ratio and survival rate of Indonesian shortfin eel (Anguilla bicolor). This research used experimental method and Completely Random Design method with five treatments. Each treatment was replicated four times. The result of this research showed that artificial feed, natural feed and combination between them were significantly difference (p<0,05) on growth rate of body wight and food convertion ratio but not significantly difference (p>0,05) on survival rate of Indonesian shortfin eel. The best growth in treatment E (1.72%), then a row followed by treatment A (1.51%), B (1.29%), D (1.25%) and C (1.25%) . The lowest feed conversion ratio obtained in treatment E (6.73) and highest feed conversion ratio obtained in treatment C (9.91). Survival rate obtained was 100%. Water quality of maintenance media of eel was the temperature 28-31°C, pH 7-8,5, dissolve oxygen 3,5-5,8 mg/l and ammonia 0,003 mg/l.