bluuebunny/crossref_metadata_2025 huggingface dataset:
A INAPLICABILIDADE DO ACORDO DE NÃO PERSECUÇÃO PENAL NA JUSTIÇA MILITAR: UMA ANÁLISE JURÍDICA
Authors: Lagoia Rodrigo Jose Vale , Almeida Andréia Alves de
Published: May 2024

O Acordo de Não Persecução Penal (ANPP), introduzido pela Lei nº 13.964/2019, conhecido como Pacote-Anticrime, surgiu como um instrumento alternativo à persecução penal tradicional, visando a desburocratizar o sistema judicial e conferir celeridade à resolução de conflitos penais de menor gravidade na fase pré-processual. A problemática será analisar quais são os impactos da não utilização do acordo de não persecução penal na Justiça Militar para o efetivo cumprimento da lei penal militar e para a garantia dos direitos fundamentais dos militares acusados. Quanto ao objetivo geral questiona-se a natureza específica dos crimes militares e os princípios basilares que norteiam o direito penal militar. Já os objetivos específicos são analisar as implicações da não aplicação do ANPP nos crimes militares e suas consequências para a efetividade do sistema de justiça criminal. Em relação à metodologia utilizando o método dedutivo e descritivo, com base em fundamentos teóricos encontrados em pesquisas bibliográficas, como documentos públicos, livros, artigos científicos e dados da internet.
(IM)POSSIBILIDADE DE PRISÃO CIVIL DOS AVÓS EM FACE DO DESCUMPRIMENTO DO DEVER LEGAL DE PRESTAÇÃO DE ALIMENTOS
Authors: Barbosa Danielle Stephany Pereira , Silveira Lara Maria Costa Guimarães , Saraiva Rodrigo Araújo
Published: May 2024

O tema da (im)possibilidade de prisão civil dos avós em face do descumprimento do dever legal de prestação de alimentos é objeto de intenso debate acadêmico e jurídico. Este Trabalho abordará a controvérsia em torno dessa questão e a importância de se discutir sobre a linha tênue entre responsabilização em casos externos e a violação dos direitos dos avós. Serão exploradas as diferentes perspectivas teóricas e legais sobre o assunto, analisando argumentos a favor e contra a aplicação dessa medida. Além disso, abordaremos casos jurisprudenciais relevantes e a legislação pertinente em diferentes países, analisando a evolução histórica e jurídica dessa questão. Serão examinados argumentos legislativos, visando compreender os fundamentos que embasam tanto a defesa quanto a crítica dessa medida. O objetivo deste estudo é oferecer uma compreensão abrangente do tema, fornecendo insights para futuras pesquisas e discussões no campo do direito de família, gerando, assim, uma melhor interpretação judicial acerca da temática.
PERFILAMENTO RACIAL NAS ABORDAGENS POLICIAIS NO BRASIL: A ILEGITIMIDADE DA FUNDADA SUSPEITA BASEADA NA RAÇA DO ABORDADO
Authors: Sousa Hyago Fellipe Freitas de , Veras Mateus Balbino de Sousa , Mourão Rosália Maria Carvalho
Published: May 2024

Este trabalho aborda o racismo estrutural e institucional no contexto da aplicação da busca pessoal no Brasil com foco no perfilamento racial. A problematização surge da interação entre a população negra e as forças de segurança pública, particularmente a polícia militar, e como o racismo se manifesta nessas interações. O objetivo é analisar casos específicos que ilustram o perfilamento racial e as falhas do sistema judiciário brasileiro, citando autores como Silvio Almeida, Rondelli, Misse, David Luiz Barbosa de Souza, Isabella Maria Nunes Ferreirinha, Tânia Regina Raitz, Juliana Santos Botelho e Geisa Mattos. A importância deste trabalho reside na necessidade de práticas antirracistas efetivas e na proteção dos direitos fundamentais para combater o racismo estrutural e institucional. O caso de Francisco Cicero dos Santos Júnior, um homem negro condenado inicialmente por tráfico de entorpecentes, como fio para trabalhar a questão do perfilamento racial.
DESAFIOS E OPORTUNIDADES PARA AS LOJAS FÍSICAS NA ERA DIGITAL: ESTUDO DE CASO EM UM BAIRRO NA CIDADE DE ILHÉUS
Authors: Fernandes Gabriel Andrade , Morett Amarildo José
Published: May 2024

As varejistas tradicionais ao longo do tempo vêm sofrendo por drásticas mudanças com o aumento significativo do comércio eletrônico. O presente estudo tem como objetivo analisar os desafios enfrentados pelas lojas físicas na era digital bem como as oportunidades que surgem nessa esfera. Aplicando um estudo de caso na cidade de Ilhéus no bairro Nelson Costa, mostrando as formas e técnicas de adaptação do comércio varejista local para se destacar em meio digital. Foi possível observar que os lojistas estão se esforçando para acompanhar o e-commerce para que possam se destacar em meia a tendência tecnológica, mesmo que tenham várias dificuldades atrelado ao objetivo.
PAPEL DO ENFERMEIRO NA GARANTIA DA SEGURANÇA DO PACIENTE CIRÚRGICO
Authors: Oliveira Deivson do Vale , Andrade Robson Vidal de
Published: May 2024

O tema discutido refere-se a importância do enfermeiro diante da segurança do paciente cirúrgico, o enfermeiro desempenha um papel de suma importância na assistência à saúde, sendo um profissional facilitador na identificação de riscos e eventos adversos, ocupando uma posição central no processo, melhorando toda a assistência na qualidade prestada. Relatar, comparar e mesurar é algumas de suas responsabilidades, bem como o enfermeiro deve colaborar na prevenção e promoção da segurança do paciente. Materiais e Métodos: para construção deste artigo, foram consultados sites de referência em nível nacional, utilizando a revisão literária de artigos científicos. Resultados: é evidente observar que o estudo propõe o impacto do profissional de enfermagem na gestão e controle de eventos adversos, frisando a colaboração fundamental e indispensável para melhor assistência oferecida a cada paciente, bem como seus familiares, garantindo maior segurança e oferecendo um cuidado mais seguro, reduzindo potenciais riscos e promovendo melhor assistência durante o cuidado. Conclusão: portanto podemos concluir que o enfermeiro tem papel relevante e de grande responsabilidade no que se refere a garantia, prevenção e promoção da segurança do paciente cirúrgico.
A NORMATIZAÇÃO DO ABANDONO AFETIVO: ALTERAÇÕES NO CÓDIGO CIVIL E ESTATUTO DA CRIANÇA E DO ADOLESCENTE PELO PROJETO DE LEI N° 3.012/2023
Authors: Leal Isadora Brandão , Lisbino Jhon Kennedy Teixeira
Published: May 2024

A presente pesquisa teve como objetivo apresentar um estudo sobre a possibilidade de normatização do abandono afetivo pelo projeto de Lei nº 3.012/2023 bem como sua conformidade com os princípios que regem a filiação constantes na Constituição Federal, levando em conta a necessidade de o instituto se estabelecer como norma no ordenamento jurídico para que seja pacificado o entendimento quanto à responsabilização civil por abandono afetivo. Inicio com análise dos princípios constitucionais sobre filiação, em seguida dos deveres inerentes ao poder familiar, inclusive, o próprio dever de afeto. A partir das análises feitas, no contexto entre pais e filhos, foi discutido como o descumprimento do dever de afeto pode ser passível de responsabilização civil ao abandonante e como os tribunais firmam seu entendimento a partir de 2006, marco importante ao reconhecimento do instituto pelo Superior Tribunal de Justiça, sendo comparadas jurisprudências em sentido contrário quanto ao reconhecimento da indenização por dano moral em razão do abandono afetivo e avaliados os votos de julgadores das demandas.
PEMETAAN KAPAL TERBENGKALAI BERBASIS WEB DI WILAYAH OPERASIONAL PERAIRAN PPN KARANGANTU
Authors: Virgianisa Tania , Rosalia Ayang Armelita , Arifin Willdan Aprizal
Published: May 2024

The current condition of the Karangantu Archipelago Fisheries Port (PPN) is still considered unfavorable because the operational area of ​​the port waters looks dirty and shabby. There are many ships that are no longer used in the Karangantu PPN operational area. Based on the results of interviews with PPN Karangantu officers, there are several things that cause ships to be abandoned in the operational area of ​​PPN Karangantu waters, including the age of the ship, costs or capital, and human resources. Abandoned ships that are not immediately handled will result in obstacles to the flow of water traffic at the port and create a risk of collision for other ships passing by. Therefore, web-based mapping of abandoned ships (WebGIS) is needed in the operational area of ​​PPN Karangantu waters. It is hoped that the results of this abandoned ship mapping can be used by the port to report abandoned ships to the center so that they can immediately take action to transport the abandoned ships. With the existence of WebGIS mapping abandoned ships, the port does not need to go directly to the field to find the location of abandoned ships because the information can be accessed via the web that has been created. Data collection on coordinate points was carried out by field survey and tagging using the GPS Map Camera application. The research results show that there are 74 abandoned ships in the Karangantu PPN operational area.
ANALISA JARINGAN, POLA DAN BUDAYA KOMUNIKASI ORGANISASI DI PT ASTRA HONDA MOTOR (AHM), MAJALENGKA
Authors: Ramadhan Fardhal Virgiawan , Anggraeni Diana
Published: May 2024

Automotive developments in Indonesia have been proven to be able to advance the Indonesian economy. This is proven by the fact that this sector is able to contribute around Rp. 99.16 Trillion. PT Astra Honda Motor (AHM) is one of the companies operating in the automotive sector that is successful in this marketing. The success achieved will certainly be related to the network, patterns, and culture of organizational communication carried out. This is because, with the formation of networks, organizational communication patterns, and culture, cooperation will increase to achieve its goals. The aim of this research is to analyze the network, patterns, and culture of organizational communication at PT Astra Motor Honda (AHM) Majalengka. The research method used is qualitative with primary and secondary data collection techniques, by conducting a Focus Group Discussion (FGD) to interpret the findings obtained. The results of this research show that AHM Majalengka has an organizational communication network and pattern, which can be seen in the communication network having several characteristics such as opinion leaders, bridges, and gatekeepers. The Organizational Communication Pattern has 2 (two) patterns, namely the Chain Communication Pattern which is found from the Main Director to the Director to the HRD Manager, while the Y Organizational Communication Pattern is found in the HRD Manager to several divisions such as Psychologist, Marketing, Account & ADM Manager, Operational Division, and Recruitment Division.
SUPER ENKRIPSI ALGORITMA ROUTE CIPHER DAN ALGORITMA VARIABLY MODIFIED PERMUTATION COMPOSITION (VMPC) UNTUK PENGAMAN FILE CITRA
Authors: Siagian Fadliansyah
Published: May 2024

Securing image files is a crucial aspect in addressing information security challenges. Super encryption is an approach that combines various cryptographic algorithms to enhance data security. In this research, we implement Super Encryption by combining two algorithms, namely Route Cipher and VMPC (Variably Modified Permutation Composition). Firstly, we employ the Route Cipher to encrypt image files by rearranging the pixels in the image using a specific mapping scheme. Subsequently, we apply VMPC, a key-symmetric encryption algorithm, to encrypt the previously modified image. The use of VMPC as the second layer aims to provide additional security by incorporating efficient and secure key-symmetric encryption. The results of this research demonstrate that the combination of Route Cipher and VMPC provides strong security for image files. This method introduces a high level of complexity for attackers attempting to decrypt the image without the correct key. Moreover, this Super Encryption offers higher confidentiality and resilience against attacks on image files compared to using a single encryption algorithm.
VISUALISASI 3D JAM GADANG BUKITTINGGI DENGAN KONSEP VIRTUAL REALITY BERBASIS ANDROID
Authors: Syukri Hamdan , Ikhwan Ali , Alda Muhamad
Published: May 2024

The research is titled "Implementation of 3D Visualization on the Tourist Attraction of Jam Gadang Bukittinggi with Android-Based Virtual Reality Concept." The main issue addressed in this study is the physical limitation faced by visitors who seek to understand the spatial conditions and information about the Jam Gadang building, resulting in suboptimal services. Consequently, visitors to Jam Gadang must obtain a special permit from the Tourism Office of Bukittinggi to access and ascend the building to its summit. Therefore, an Android-based Virtual Reality application is needed to allow users to comprehend the spatial conditions and information by virtually entering and ascending the Jam Gadang building without the need to be physically present. Information will be presented in the form of panels within the virtual environment, accompanied by a narrated voice.
Diez años de la aprobación de la Ley 19/2013
Authors: Ginesta Rodríguez Victor , Pano Puey Ester , Medir Tejado Lluís , Magre Ferran Jaume
Published: May 2024

Transcurrida una década desde la implementación de la Ley 19/2013, carecemos de una visión comparada del nivel de cumplimiento de la norma que incluya una selección amplia de los ayuntamientos españoles. A pesar de la existencia de estudios sobre el cumplimiento de la transparencia activa y de la presencia de varios índices, la mayoría de las contribuciones están centradas exclusivamente en los ayuntamientos de más población. Con el objetivo de subsanar esta carencia, hemos monitorizado los patrones de transparencia activa de los ayuntamientos españoles mayores de 10.000 habitantes y de una selección de 300 inferiores a 10.000. En total, hemos analizado el cumplimiento normativo de 1.031 municipios españoles. Para revisar el cumplimiento, hemos construido un índice con los principales elementos de la Ley. Los resultados arrojan una implementación dispar e insuficiente de las obligaciones de publicidad activa y, para un mejor cumplimiento normativo, se debería promover un sistema  de monitorización externo del cumplimiento que promueva e incentive prácticas y experiencias y suponga una mayor difusión de los principios de la norma, así como alejarse de la homogenización, estableciendo articulaciones específicas de las obligaciones normativas en función de la naturaleza, la dimensión y la capacidad institucional.
¿Hacia una nueva cultura de la participación en el ámbito local?
Authors: Nicasio Varea Blanca
Published: May 2024

La presente investigación tiene como objetivo examinar el grado de implicación de las administraciones locales para promover una cultura política más participativa. En concreto, se estudian, de forma comparada, los instrumentos que facilitan, los ayuntamientos de la Comunidad de Madrid, Cataluña, Comunidad Valenciana, Islas Baleares y Región de Murcia a través de sus páginas web, a los ciudadanos para participar en los asuntos públicos, en el año 2022. Para ello, se emplea una metodología basada en la aplicación de los indicadores constatados en el Mapa Infoparticipa. De los 52 indicadores, se analizan los nueve que están directamente relacionados con el fomento de la participación ciudadana en el nivel local. Los resultados evidencian, de un lado, que las CCAA con mayor trayectoria en la implementación de Infoparticipa, y con mayor número de municipios medianos y grandes (más de 20.000 habitantes) cuentan con un mayor grado de cumplimiento de los indicadores. Y, de otro lado, que aquellos indicadores que implican la publicación de los resultados de los instrumentos de participación y del derecho de acceso se cumplen en menor medida.
L’explosion des formes de vie
Authors: Chapouthier Georges , Maurel Marie-Christine
Published: May 2024

L’une des caractéristiques essentielles des êtres vivants concerne l’explosion de leurs formes, liée à la diversité des milieux auxquels ils se sont adaptés. Fruit de la collaboration de spécialistes internationaux, cet ouvrage analyse la multiplicité de ces morphologies. Il traite de l’origine des formes, de leur rôle dans la définition du vivant et des relations entre forme et fonction. Il expose le rôle des gènes et de l’épigenèse ainsi que les formes des bactéries, des protistes et des végétaux. L’explosion des formes de vie étudie la mémoire des animaux et leurs processus sensoriels, les formes que prennent les robots (construits à l’image du vivant) de même que les technologies médicales visant à rétablir des formes vivantes endommagées. Enfin, l’ouvrage questionne une construction commune dans la diversité des formes ainsi que l’idée d’un abandon de la forme, possible vice caché de certaines philosophies modernes.
Le Système solaire 1
Authors: Encrenaz Thérèse , Lequeux James
Published: May 2024

Cet ouvrage présente une vision globale et synthétique de la planétologie, c’est-à-dire de l’étude des objets du Système solaire. Au cours des dernières décennies, la planétologie a connu une véritable révolution, marquée en particulier par la découverte de la ceinture de Kuiper au-delà de Neptune, puis par celle des planètes extrasolaires, ainsi que par l’exploration spatiale d’objets toujours plus lointains. Elle est aujourd’hui à la croisée de nombreuses disciplines : astronomie, géophysique, géochimie, biologie. Cet ouvrage traite, dans un premier temps, du Système solaire dans son ensemble, offrant une présentation générale des objets qui le composent et de sa place dans la Galaxie. Il traite également des systèmes planétaires, des exoplanètes et de l’interaction des objets du Système solaire avec le milieu interplanétaire. Il analyse enfin les planètes telluriques et géantes.
Weather Type Reconstruction using Machine Learning Approaches
Authors: Pfister Lucas , Wilhelm Lena , Brugnara Yuri , Imfeld Noemi , Brönnimann Stefan
Published: May 2024

Abstract. Weather types are used to characterise large–scale synoptic weather patterns over a region. Long–standing records of weather types hold important information about day–to–day variability and changes of atmospheric circulation and the associated effects on the surface. However, most weather type reconstructions are restricted in their temporal extent as well as in the accuracy of the used methods. In our study, we assess various machine learning approaches for station–based weather type reconstruction over Europe based on the CAP9 weather type classification. With a common feedforward neural network performing best in this model comparison, we reconstruct a daily CAP9 weather type series back to 1728. The new reconstructions constitute the longest daily weather type series available. A detailed validation shows considerably better performance compared to previous statistical approaches and good agreement with the reference series for various climatological analyses. Our approach may serve as a guide for other weather type classifications.
Development of Internet-of-Things-Based Controlled-Source Ultra-Audio Frequency Electromagnetic Receiver
Authors: Lin Zucan , Zhang Qisheng , Zhou Keyu , Zhang Xiyuan , Wang Xinchang , Zhang Hui , Liu Feng
Published: May 2024

Abstract. Electromagnetic exploration, characterized by its low cost, wide applicability, and high operational efficiency, finds extensive applications in fields such as oil and gas exploration, mineral prospecting, and engineering geology. Traditional controlled-source electromagnetic detection methods are typically confined to operating frequencies below 250 kHz, resulting in insufficient detection accuracy for applications such as shallow and intermediate-depth exploration, thereby constraining their performance in high-resolution imaging. To address these challenges, we propose a controlled-source ultra-audio frequency electromagnetic receive system based on the Internet of Things (IoT). We investigate cascaded digital filtering and sampling techniques to extend the receiver's sampling rate range, thereby elevating the operating frequency of controlled-source electromagnetic acquisition from the conventional maximum of 250 kHz to 1 MHz. The receiver achieves a sampling rate of up to 2.5 MHz, comprising three magnetic field measurement channels and two electric field measurement channels. The instrument is compact, lightweight, capable of real-time data storage locally, and real-time data transmission to an upper computer. Additionally, IoT technology is introduced, leading to the design of a cloud-based real-time remote control and data acquisition scheme. Experimental results demonstrate the stability of the instrument, meeting the requirements of field exploration.
Mu’înü’l-Mürîd’de /+DIn/ Şeklinin Hâl İşlevleri
Authors: ÇELİK Özge
Published: May 2024

The functions of case suffixes in current grammar teaching are quite limited. Generally, shape is taken as a basis and no evaluation is made according to the function of the suffix in the suffix sequence. In this study, the functions of the /+DIn/ form as a case suffix in the work called Mu'înü'l-Mürîd from the Khwarezmian Turkish period are discussed. Keywords: Mu’înü’l-Mürîd, suffix, function, +DIn, positional suffix.
Documentary Depth of Hadith Transmission
Authors: Aljoumani Said , Reier Benedikt
Published: May 2024

The transmission of hadith prompted substantial documentation and subsequent archiving. This article presents a recently rediscovered type of document belonging to this paper trail: audition attendance lists (awrāq al-samāʿ). Preceding the better-known audition certificate (samāʿ), an audition attendance list was sometimes used in the transmission of particularly long books in order to keep track of the attendance of sometimes hundreds of participants in audition sessions. Here we concentrate on one audition attendance list produced in the ninth/fifteenth century in Cairo for a transmission of the most famous hadith collection, the Ṣaḥīḥ al-Bukhārī. We introduce this kind of document, propose a reading of our particular sample, and discuss certain functions of audition attendance lists. We argue that these lists reveal a hitherto unknown depth in the documentary machinery of textual transmission.
Determinants of Classroom Management as Perceived by Female Students at the Secondary Level
Authors: Aslam Sadia , Qayuum Aminah , Manzoor Adeela , Anwar Maria , Salman Muhammad , Hassan Zahid , Ali Saif , Peerzado Moula Bux , Usman Muhammad
Published: May 2024

Effective classroom management is directly associated with a positive class environment and positive outcomes. In this study, we examined the different determinants of the classroom management. This study was conducted in four secondary schools (private) in the District of Faisalabad in Punjab province. Students from class 10th were considered as the population, thus from each selected school, the total number of students was 350 which served as the population of this study. All the participants were female students. Of the total population, 25 students were chosen from each selected school, thereby the total sample size of the study was 100 female students. A questionnaire was administered for the data collection and was analyzed using Statistical Package for Social Sciences (SPSS). Results revealed that perceived challenges faced by students in the classroom, with mental illness, lack of self-confidence, personal issues, and poor listening emerging as the most prominent concerns. Whereas, factors perceived to significantly affect classroom management, highlighting disabilities, lack of interest, and self-esteem as primary considerations for educators and administrators. Investing in teacher training programs that focus on aspects of classroom management can enhance their ability to create a positive and conducive learning environment.
Analyzing effects of managerial skills of government high school heads on school performance: a study of schools of Larkana District
Authors: Bhutto Muhsin Khan , Sumeera Ms , Ilyas Muhammad , Sarwar Maria , Channa Mansoor Hussain , Memon Awais ur Rehman
Published: May 2024

Abstract
Present study aimed at investigating the effects of the managerial skills of school heads  on academic performance of students in district Larkana, Sindh. The major objectives of the study was to determine specific managerial skills of school heads, effects of those skill of performance of high schools of Larkana and strategies to improve them. Saturated sampling techniques was utilized for selecting respondents of present study. Additionally, twenty five government high heads of Larkana District were considered for collecting data.  Close-ended and open-ended questionnaires were utilized for gathering data. Reliability was tested using Cronbach Coefficient Aloha where coefficient 0.757 was considered to be realizable. Analyzed data were showed in APA style tables. The analyzed data showed that most of the government high school heads of Larkana District were able to utilize numerous managerial skills that were effecting school performance. However, for further improving their skills different strategies were needed to be implemented. It was also suggested that high school heads should be dedicated to their built-in managerial skills and use them in their daily duties. While, they also should facilitate numerous opportunities to attend training and workshops for positively effecting the school performance.
Pengaruh Aromaterapi Lemon Dalam Mengurangi Emesis Gravidarum Pada Ibu Hamil Trimester 1 Di Desa Taddan Kecamatan Camplong Kabupaten Sampang
Authors: Amin Edysuryadi , Nadine W.P Aurellya
Published: May 2024

Ibu hamil pada trimester pertama akan mengalami mual muntah (emesis gravidarum) yang dapat mengakibatkan ketidaknyamanan, jika mual muntah terjadi secara berlebihan dan mengganggu aktivitas sehari hari akan menimbulkan hypermesis gravidarum terhadap ibu hamil. Kondisi emesis gravidarum merupakan masalah yang umum dan kerap dialami pada trimester pertama kehamilan, mual muntah umumnya terjadi pada pagi hari. Desain penelitian Quasi Experiment, One Group Pretest-Posttest. Populasi dan sampel dalam penelitian ini seluruh ibu hamil trimester 1 di Desa Taddan Sampang yang berjumlah 13 orang dengan teknik total sampling. Pengumpulan data menggunakan lembar kuesioner dan observasi. Data yang diperoleh diolah menggunakan metode editing, coding, scoring, tabulating, interpretating dan analisis dengan uji statistik Wilcoxcon. Sebagian besar responden sebanyak 7 orang (54%) mengalami emesis gravidarum tingkat berat sebelum dilakukan intervensi. Seluruh responden 13 orang (100%) mengalami emesis gravidarum tingkat ringan setelah dilakukan intervensi. Berdasarkan hasil bivariat Uji Wilcoxon didapatkan p value 0.001< 0.05 yang bermakna terdapat Pengaruh Aromaterapi Lemon dalam Mengurangi Emesis Gravidarum pada Ibu Hamil Trimester 1 di Desa Taddan Kecamatan Camplong Kabupaten Sampang. Terdapat pengaruh antara dua variabel. Diharapkan ibu hamil trimester 1 dapat menerapkan pemberian aromaterapi lemon   sebagai alternatif non farmakologis untuk mengatasi emesis gravidarum.
SYNTHESIS AND CHARACTERIZATION OF BIOPLASTICS FROM CORN-STALK FIBER AND CHITOSAN
Authors: Rokhati Nur , Prasetyaningrum Aji , Samsudin Asep Muhamad , Khoirudin Fakhri Santo , Astuti Umi Widi , Anggraini Widyah
Published: May 2024

The plastics used by the public are generally made of petrochemicals which take a long time to degrade completely. One of the solutions to overcome the problem of plastic waste is to make produce bioplastics. Bioplastics are made from renewable natural materials and are environmentally friendly. One of the materials that can be made into bioplastic is chitosan. Chitosan has been widely used in the packaging industry, especially in food packaging, because of its biocompatibility, biodegradability, and non-toxicity. However, the relatively high price of chitosan will limit the use of chitosan film in various applications. In this study, bioplastics were made from chitosan and cellulose. Cellulose was obtained from the corn-stalks waste extract. The results showed that the glycerol addition increases the swelling degree, decreases the tensile strength, increases the elongation break, and accelerates the degradation of bioplastics. The optimum conditions for producing bioplastics were obtained by 1% glycerol addition, cellulose: chitosan ratio of 25:75, and 1% glutaraldehyde addition.
THE MAKING OF AN AUTOMATIC DOG FEEDING DEVICE WITH THE USE OF ARDUINO UNO AND SERVO MOTOR
Authors: Haguisan III Dr. Ismael A. , Jr. S. Yap James Allen , P. Ignacio Elisha Railey , T. Gaorano Sir Jhorel , P. Lising Manuel IV , C. Tadeje Chrystal Brianne
Published: May 2024

As individuals continue to live busy lifestyles, neglect remains prevalent among dog owners. Therefore, malnutrition among dogs, caused by improper feeding habits, remains a rampant issue worldwide. The main objective of this study is to create an automatic dog feeding device out of Arduino Uno and Servo Motor. For the purpose of dog food dispensing, the Arduino Uno, an open-source electronics platform based on simple hardware and software, was used in the servo motor operations. Thus, the device utilized two main components Methodology: The researchers utilized the experimental design of research as well as the quantitative method. The results of the study show the dispensing capabilities of the automatic dog feeding device under increasing loads. Additionally, the servo motor’s dispensing precision was proved with slight deviations from the expected weight to the actual weight averages. Moreover, the Arduino Uno’s dispensing accuracy and its reliability was tested wherein the device dispensed on cue with minimal deviations in time. The results demonstrated that the automatic dog feeding device can effectively dispense dog food meeting the various criteria tested. The discussion states the significant contribution of this study toward pet care technology and the field of engineering. Asserting that the findings of this study allow for better understanding of the role of technology in the pet industry. Lastly, in accordance with the limitations of the study, it is recommended that the design and functionality of the device may be enhanced and improved by later researchers.
ОРНЫҚТЫ ДАМУ ТҰЖЫРЫМДАМАСЫН ІСКЕ АСЫРУ ҮШІН МИНЕРАЛДЫ-ШИКІЗАТ РЕСУРСТАРЫН ПАЙДАЛАНУДЫҢ ӨЗЕКТІ МӘСЕЛЕЛЕРІ
Authors: BIRYUKOV V.
Published: May 2024

The article gives a brief description of the actual problems of the use of mineral resources for the implementation of the concept of sustainable development, as well as possible solutions to the depletion of mineral reserves of the Republic of Kazakhstan.

Мақалада орнықты даму тұжырымдамасын іске асыру үшін минералды-шикізат ресурстарын пайдаланудың өзекті мәселелеріне қысқаша сипаттама берілген, сондай-ақ Қазақстан Республикасының минералды шикізат қорларының сарқылу мәселелерін шешудің ықтимал жолдары келтірілген.

В статье дана краткая характеристика актуальных проблем использования минерально-сырьевых ресурсов для реализации концепции устойчивого развития, а также приведены возможные пути решения вопросов истощения запасов минерального сырья Республики Казахстан.
On graded S−comultiplication modules
Authors: Hamoda Mohammad , Al-Zoubi Khaldoun
Published: May 2024

In this paper, we introduce the concept of graded S−comultiplication modules.  Several results concerning graded S−comultiplication modules are proved.  We show that N is a graded S−second submodule of a graded S−comultiplication R−module M if and only if Ann_R(N) is a graded S−prime ideal of R and there exists x ∈ S such that xN ⊆x-  for every x- ∈ S.
Generalized solutions of the Cauchy problem involving $\Phi$-Caputo fractional derivatives
Authors: Taqbibt Abdellah , El Bezdaoui Latifa , Elomari M'hamed , Chadli Lalla Saadia
Published: May 2024

The main objective of this research paper is to embed $\Phi$-Caputo fractional derivative in the Colombeau algebra of generalized functions and we investigate the existence and uniqueness of the Cauchy problem involving $\Phi$-Caputo fractional derivatives in the extended Colombeau algebras. Finally, we give anexample of how the ideas presented in the document can be applied.
On recurrent sets of operators
Authors: Amouch Mohamed , Benchiheb Otmane
Published: May 2024

An operator $T$ acting on a Banach space $X$ is said to be recurrent if for each $U$; a nonempty open subset of $X$, there exists $n\in\mathbb{N}$ such that $T^n(U)\cap U\neq\emptyset.$ In the present work, we generalize this notion from a single operator to a set $\Gamma$ of operators. As application, we study the recurrence of $C$-regularized group of operators.
Evaluation of Ketamine after subacute low dosage Lipopolysaccharide-activated Microglia produced depressive-like phenotype in mice
Authors: Praharaj Shuvranshu , Kaliyamoorthy Kalaichelvan Vandurayanpet , Murugan Vedigounder , Ahmad Ishtiyaque
Published: May 2024

Depression is a common mental illness, with an estimated 3.8% of global population affected. Peripheral administration of lipopolysaccharide (LPS) culminate in a distinct depressive-like behavioral syndrome, measured by increased duration of immobility in the forced swim test (FST) and anhedonia in sucrose preference tests (SPT). After 6 days of LPS stimulation, we established a depression model in C57BL/6 mice, where animals started to recover from the B/W loss brought on by the LPS and the significant immunological response that resulted in microglial activation in the brain. There was a modulation in the relative weight of the thymus and spleen observed under these experimental conditions. Ketamine having a quick onset of action reduces the emergence of depressive-like behaviour by modifying the intensity of Iba-1 in stressed mice by reducing swimming behaviour and boosting desire for sucrose. However, it did not result in an improvement in the number of microglia or CD11b cells activation in the hippocampus of C57BL/6 mice or in the relative weights of the spleen and thymus. In summary, these data emphasizes that Ketamine treatment improves depressive-like behavior and Iba-1 immunoreactivity, but the hyperactive in terms of number of microglia and CD11b expression were not modulated in the mouse hippocampus.
Development and Validation of UV Spectrophotometric Method for Simultaneous Estimation of some SGLT-2 and DPP-4 inhibitor in Bulk and Pharmaceutical Dosage Form
Authors: Patel Grishma , Maradia Rajnikant , Soni Tejal , Suhagia Bhanubhai , Meshram Dhananjay
Published: May 2024

The result of pharmaceutical industry research for the new class and the new combination of drugs for the treatments of diabetes is the newly approved combination of Remogliflozin etabonate (RGE) and Teneligliptin Hydrobromide hydrate (TG). For the quality control of this formulation, the smart, reproducible and non-sophisticated spectroscopic techniques were developed by modification of UV spectra. The proposed methods exhibited Beer’s law in the range of 10 to 60µg/ml and 5 to 30µg/ml for RGE and TG correspondingly. The mean percentage recovery was found to be in the range of 98.60 to 101.55 for RGE and 99.87 to 100.21 for TG. Further, both analytes were quantified from the formulation using proposed spectroscopic methods with high accuracy. The suggested technique is simple, accurate and reproducible, hence could be used for regular quality control of formulation consisting of RGE and TG. The developed method can be used for analysis of stability samples and routing quality control evaluation in tablet formulation.
Simultaneous Estimation of Naltrexone Hydrochloride and Zonisamide in Synthetic Mixture by RP-HPLC Method
Authors: Dhaduk Sejal , K. Patel Nilesh , B. Patel Ashok , J Vyas Amitkumar , I. Patel Ajay , A. Gol Dhruvanshi
Published: May 2024

A simple, rapid, precise, and reproducible RP-HPLC method development and validation done for simultaneous estimation of Naltrexone Hydrochloride and Zonisamide in synthetic mixture. The isocratic method was developed usinɡ a Water Symmetry C18 (250 mm X 4.6 mm, 5 µm) column. Mobile phase composition was Phosphate Buffer: Methanol (75:25 %V/V) (Buffer-1.36 ɡ of KH2PO4 in 1000 ml adjust pH 3.0 ± 0.05 with OPA.), flow rate 1 ml/min and detection carried out at 230 nm at column temperature 30ºC. The injection volume was 10µl with run time of 10 minutes. Parameters such as linearity, precision, accuracy, recovery, specificity and robustness are performed as per ICH ɡuidelines Q2(R1). Retention time of Naltrexone Hydrochloride and Zonisamide were found to be 3.92 min and 8.15 min respectively. The developed method found linear in the ranɡe of 1-10 µɡ/ml for Naltrexone Hydrochloride and 2.84-142 µɡ/ml for Zonisamide (R2 = 0.9999 for both druɡs). The % Recovery were found to be 99.39 %-100.70 % and 98.91 %-100.59 % for Naltrexone Hydrochloride and Zonisamide respectively. The RSD for both druɡ were less than 2 for precision, specificity and robustness.
Design, Facile synthesis, and Characterization of sulfonamide derivatives combined with amino acids and other drugs targeting HER2
Authors: Ramzy Kattan Rama Mohammad , Ben Hadda Djamila , Balash Amir , Fawaz Chehna Mustapha
Published: May 2024

Researchers have discovered that tyrosine kinase plays a significant role in cancer development. As a result, certain studies focused on synthesizing sulfonamide compounds due to their potent tyrosine kinase inhibitory (TKI). The designed compounds were docked against (HER2) human epidermal growth factor receptor 2 (PDB ID: 3pp0) to identify potential prospects for new cancer drugs. Docking studies using Molegro virtual docker (MVD) revealed the most favorable binding energy among our compounds. In total, all synthesized compounds had binding energies ranging from (-112.893 to -154.396kcal/mol) corresponding to (3a and 1a) respectively. It was found that compound 1a possessed the best binding energy value of synthesized compounds (-154.396 kcal/mol) compared to the recommended drug; trastuzumab (-133,419kcal/mol). Several of the newly designed sulfonamide derivatives were synthesized. An alkaline phase was used in our synthesis to combine some amino acids, sulfamethoxazole, and sulfadiazine with benzenesulfonyl chloride derivatives. The synthesis method was simple and cheap with yields ranging between (60.4% - 80%). Nuclear magnetic resonance spectroscopy, mass spectrometry, and infrared spectroscopy were used to characterize our compounds.
Nano Formulation and Evaluation of Atorvastatin Mouth Dissolving Tablets
Authors: Subramanian L. Sai , Gayathri R. , Karthikeyan Karthikeyan , Dhivyadharshini R. , Subramanian S.
Published: May 2024

Atorvastatin calcium is an anti-hyperlipidemic drug that competitively inhibit HMG-CoA reductase and decrease production of cholesterol in liver. This statin derivative is highly metabolized in gut wall and liver so that it produces only 14% oral bioavailability. In this study we aim to improve the bioavailability of BCS II drug atorvastatin calcium in the formulation of mouth dissolving tablet, which enters the blood stream via facial, jugular artery and vein, by penetrating the lipid membrane when the tablet disintegrates. The Atorvastatin – chitosan nanoparticles was formulated by freeze drying of colloidal solution of nanoparticles. Super disintegrant like croscarmellose sodium, crospovidone, and sodium starch glycolate were added and tested for its dispersion properties. The prepared formulation shows enhanced rate of dissolution and may helpful by avoiding first pass metabolism and to achieve maximum bioavailability. Further the polymeric nano formulation (atorvastatin-chitosan nano particle) allows drug to penetrate much faster and dissolve the drug in saliva. Finally, the prepared formulation is evaluated by pre formulation studies, pre compression evaluation, post compression evaluation and the result of the study revealed that atorvastatin chitosan nanoparticles with size of 406 nm and PDI 0.246 had 118% dissolute in 10 min and shows enhance bioavailability.
The Relationship Between Ethnicity and Socioeconomic Deprivation as Determinants of Health: A Systematic Review
Authors: Coates Melanie JP , Bhardwaj Shah Aroon , Igwe Richard , Wan Yize I
Published: May 2024

Background: Ethnicity and Socioeconomic Status (SES) are well known social determinants of health. However, the impact of the intersection between ethnicity and SES on health remains poorly understood, with many studies examining these factors separately. Methods: We conducted a systematic review using MEDLINE (PubMed), EMBASE, and The Cochrane Library databases. Studies were eligible if they compared outcomes defined by mortality, attendance, readmission, or hospital length of stay, for any acute or chronic illness, according to one or more measures of both ethnicity and SES in adult patients (≥18 years of age) attending primary care or admitted to hospital. Results: Nine studies met eligibility criteria. There was significant heterogeneity in cohort demographics, key variables, and outcome measures. Therefore, qualitative analysis was used. Definitions and categories of ethnicity were inconsistent, using race, country of origin, and sociocultural characteristics. Definitions of SES varied, with studies using between one and seven metrics. Different sub-categories were often used, even when the same metric was utilised. Primary outcomes were mortality (n=7) or admissions-related (n=2). Approaches varied between studies, regarding cause, time periods, and end points. Of those looking at mortality, four reported seeing an interaction between ethnicity and SES groups on outcomes.
Bibliometric Analysis of Quality Studies in Healthcare During the Pandemic
Authors: Ugrak Ugur , Şen Harika , Kavak Demet
Published: May 2024

Introduction and Objective: COVID-19 has significantly affected healthcare processes along with quality studies in healthcare services. This research aims to reveal the bibliometric profile of quality studies in healthcare during COVID-19.
Materials and Methods: The data were obtained from the Web of Science (WoS) core collection (n=470). The search criteria were used to access quality studies conducted in healthcare during the pandemic. Bibliometric analysis was made with the SciMAT program.
Results: During COVID-19, quality studies in healthcare focused on mental health subjects. "Quality of life" (n=82) and "mental health" (n=80) were the most frequent keywords. The themes of "insomnia," "depression," and "physical activity, which also affect the quality of life, were among the most frequent subjects.
Conclusion: During the pandemic period, research focused on subjects of quality of life rather than managerial quality research. Although health outcomes for patients and healthcare professionals are a priority in pandemics, managerial quality issues must be addressed from a broader perspective.
Impact of the economic crisis and drug shortage on Lebanese cancer patients’ care
Authors: Eid Dollen , Jabbour Jad , Moujaes Elissar , Kourie Hampig Raphael , Safieddine Maissa , Kattan Joseph
Published: May 2024

BACKGROUND

As a consequence of the economic crisis, the sociopolitical instability and the advent of the coronavirus disease-19 pandemic, nested challenges faced the Lebanese healthcare system. These have resulted in critical shortages of essential resources, including medications vital for oncologic patients.

AIM

To assess the ramifications of the ongoing economic crisis on oncology patient care focusing on our outpatient oncology department.

METHODS

A questionnaire was distributed during the month of February 2022 to oncology patients in Hôtel Dieu de France University Hospital in Beirut during their outpatient therapy. The primary objective was to assess the far-reaching impact of the economic crisis on patient care and the resulting psychological implications.

RESULTS

Among 182 interviewed patients, 31.87% experienced treatment interruption mainly due to acute drug shortages. Despite 87.91% of the patients benefiting from third-party coverage, 69.60% had to self-pay for their medications leading to 69.78% of patients perceiving that healthcare was more difficult to access after 2020. Psychologically, one-third of the patients exhibited symptoms of anxiety and/or depression, with 7 patients reporting suicidal ideations. Notably, 37.93% of patients who interrupted cancer treatment reported a history of comorbidities, and 89.66% who altered their treatment cited financial difficulties.

CONCLUSION

Lebanese cancer patients face complex challenges spanning economic, healthcare, and psychological realms. Income inequalities exacerbated by the economic crisis hindered healthcare access.
Integrating disulfidptosis-related long noncoding RNAs in colorectal cancer prognosis: A path to precision medicine
Authors: Zhang Shi-Yan
Published: May 2024

This commentary explores the burgeoning field of disulfidptosis-related long noncoding RNAs (lncRNAs) in the prognosis and therapeutic targeting of colorectal cancer (CRC). By evaluating recent research, including the pivotal study "Predicting colorectal cancer prognosis based on long noncoding RNAs of disulfidptosis genes" by Wang et al , this analysis underscores the critical role of lncRNAs in deciphering the molecular complexities of CRC. Highlighting the innovative methodologies and significant findings, I discuss the implications for patient survival, therapeutic response, and the potential of lncRNAs as biomarkers for precision medicine. The integration of bioinformatics, clinical databases, and molecular biology in these studies offers a promising avenue for advancing CRC treatment strategies and improving patient outcomes.
Representatividade da Rede Nacional de Vigilância Epidemiológica Hospitalar na vigilância das infecções sexualmente transmissíveis e AIDS no Brasil: análise das notificações de 2018 a 2022
Authors: Tavares Jonatas Bezerra , Casaroto Vinicius de Souza , Rodrigues Samara Carolina , Guimarães Luciana Nogueira de Almeida , Silva Camila Pinto da , Gonçalves Francisco Silvanei dos Santos , Saraiva Hariadny Ashlley Neves Clemente , Garcia Marcio Henrique de Oliveira
Published: May 2024

Introdução: A Rede Nacional de Vigilância Epidemiológica Hospitalar (Renaveh) é constituída de Núcleos Hospitalares de Epidemiologia (NHE), instituídos no âmbito de hospitais estratégicos vinculados ao Ministério da Saúde, e desempenha um importante papel no Subsistema Nacional de Vigilância Epidemiológica do Brasil. A Rede se encontra em ampliação, partindo de 190 hospitais vinculados em 2010 para 805, em 2022. Objetivo: Analisar a representatividade e o perfil das notificações compulsórias de infecções sexualmente transmissíveis (IST) da Renaveh na vigilância das IST/AIDS no Brasil. Métodos: Foi analisada a base anonimizada das notificações de AIDS, hepatites virais, gestante com HIV, criança exposta ao HIV, sífilis, sífilis congênita e sífilis em gestante do Sistema de Informação de Agravos de Notificação (SINAN), no período de 2018 a 2022, por meio dos softwares R e Microsoft Excel. Os hospitais vinculados à Renaveh, em cada período, foram selecionados pelo Cadastro Nacional de Estabelecimentos de Saúde. Foi calculado o valor preditivo positivo (VPP) para sífilis e hepatites virais da rede em comparação com os demais notificadores. Resultados: Foram realizadas 2.121.542 notificações no período, das quais os hospitais da Renaveh representaram 7,7%, decrescendo de 8,8% em 2018 para 6,2% em 2022. A maior representatividade da rede foi para a sífilis congênita (20,1%) e para o HIV em gestante (19,1%). Os hospitais da região Sudeste foram os que mais notificaram (35,1%), seguidos da região Nordeste (30,9%) e, por último, da região Centro-Oeste (5,6%). O VPP para a sífilis foi de 89%, e de hepatites virais, 66,1%. Conclusão: Houve aumento das notificações das IST/AIDS nos demais serviços notificadores e diminuição da representatividade geral da Renaveh, possivelmente pelo aumento da descentralização do diagnóstico. Entretanto, a Rede ainda notifica cerca de 1/5 dos casos de sífilis congênita e de gestantes com HIV.