bluuebunny/crossref_metadata_2025 huggingface dataset:
Yhteisöllinen oppiminen hoitotyön simulaatio-opetuksessa
Authors: Salo Virpi , Rikala Pauliina , Ylönen Minna , Vähäsantanen Katja , Hämäläinen Raija
Published: June 2024

Terveysalan opinnoissa yhteisöllistä oppimista ja simulaatiota hyödynnetään yhä enemmän. Tutkimuksemme tuottaa tietoa yhteisöllisestä oppimisesta hoitotyön simulaatio-opetuksen kontekstissa. Simulaatio-opetuksen yleinen tavoite on valmistaa ammattikorkeakouluopiskelijoita kohtaamaan työelämän keskeisiä potilastilanteita.
Selvitämme, millaisia yhteisöllistä oppimista tukevia ja haastavia tekijöitä sairaanhoitajaopiskelijat kokevat hoitotyön yhteisöllisessä simulaatio-opetuksessa. Tutkimusaineistona käytimme opiskelijoiden kirjoittamia verkkopäiväkirjoja, jotka analysoimme temaattista analyysia hyödyntäen.
Tutkimustulokset kuvaavat yhteisöllistä oppimista tukevia ja haastavia tekijöitä. Yhteisöllistä oppimista tukeviksi tekijöiksi opiskelijat kuvasivat opiskelijaa itseään, esimerkiksi rooleissa toimiminen ja motivaation ylläpitäminen, sekä ryhmää koskevia tekijöitä, kuten vertaistuen saaminen, sitoutuminen yhteiseen tekemiseen ja dialoginen vuorovaikutus. Opiskelijoiden yhteisöllistä oppimista haastavat epämiellyttävät kokemukset, parityöskentelyn jännitteet, rooleihin sisältyvät rasitteet simulaatioissa ja oppimiskeskustelun hankaluudet.
Tuloksia voidaan hyödyntää simulaatio-opetuksen suunnittelussa ja toteutuksessa. Tulosten pohjalta erityisen tärkeää on kiinnittää huomiota siihen, että opiskelijat saavat toimia erilaisissa rooleissa simulaatio-opetuksessa. Simulaatioiden jälkeen tulee varata riittävästi aikaa opettajan ja opiskelijoiden yhdessä käytäviin oppimiskeskusteluihin.
Minne menet, demokratiakasvatus?
Authors: Hämäri Severi
Published: June 2024

Lupaus paremmasta avaa huolellisesti sekä suomalaisen demokratiakasvatuksen nykytilaa että tulevaisuutta. Demokratiakasvatusta ajankohtaisempaa aihetta tuskin on. Politiikka ja kysymys soveliasta demokraattisista tavoista vaikuttaa siihen suorastaan tulvii kansalaisten silmille, kun yleislakot seisauttavat maan ja hallitus leikkaa monien kansalaisten ja kansalaisyhteiskunnan vakiintuneita tukia.
”Aikuiskasvatustieteen merkitys korostuu yhteiskunnan murroksissa”
Authors: Korhonen Mari
Published: June 2024

Haaga-Helia ammatillisen opettajakorkeakoulun yliopettaja Jani Siirilä, 43, pyrkii työllään vahvistamaan tulevaisuuden ammatillista osaamista sekä ammattikasvatuksen profiilia.
Lukupiiri virittää tutkimukseen perustuvan dialogin
Authors: Jaakkola Maarit
Published: June 2024

Lukupiiri virittää tutkimukseen perustuvan dialogin Tutkimustieto kuuluu kaikille, ja siitä voi keskustella, vaikka ei itse tekisi tutkimusta. Lukupiiri tuo ihmisiä yhteen pohtimaan tutkittua tietoa ja vaihtamaan ajatuksia sen pohjalta. Näin perustat oman lukupiirin.
Summaries
Authors: Clarke Sario Esko
Published: June 2024

Tiedeartikkelien suomen- ja englanninkieliset tiivistelmät.
Politiikkaa vai harhaluuloja?
Authors: Hämäri S
Published: June 2024

Salaliittoteorioiden politiikat kokoaa yhteen, miten salaliittojen kaltaiset uskomukset muokkaavat yhteiskuntaa ja kuinka niitä käytetään politiikan teossa Suomessa ja maailmalla. Vaikka aiemmat kirjat salaliittoteorioista tarjoavatkin lukijalle lavean kuvan ilmiöstä, yhteiskuntatieteilijä Ari-Elmeri Hyvönen ja uskontotieteilijä Niko Pyrhönen tuovat keskusteluun uuden näkökulman: salaliittouskomusten kasvavan roolia politiikassa ja niiden vaikutuksen.
Tekoäly – ystävä vai vihollinen?
Authors: Sinkkonen Merja , Rintala Tuula-Maria
Published: June 2024

Tietotekniikkaan erikoistunut tietokirjailija Petteri Järvinen tarjoaa tuoreessa Tekoäly ja minä -kirjassaan syvempää ymmärrystä tekoälystä. Hän keskittyy asioihin, joita tekoäly ei vielä osaa tehdä. Heti alkuun hän myös toteaa, että älyn määritteleminen on liki mahdotonta, eikä tekoäly ole samanlaista kuin ihmisäly.
Comparison of Outcomes after Wavefront-optimized and Topography-guided Transepithelial Photorefractive Keratectomy
Authors: Kim SooJin , Na Sungjin , Choi Sangkyung , Choi Sung-Ho
Published: June 2024

Purpose: To evaluate the outcomes of wavefront-optimized (WFO) and topography-guided (TG) transepithelial photorefractive keratectomy (transPRK) in the treatment of myopia and myopic astigmatism.Methods: Patients who underwent transPRK using the WaveLight EX500 excimer laser for the correction of myopia and myopic astigmatism between January 2022 and March 2023 were divided into groups of WFO transPRK (77 eyes of 36 patients) or TG transPRK (63 eyes of 31 patients) in this retrospective, observational cohort study. The preoperative and postoperative 3-month refractive and visual outcomes of the two groups were analyzed.Results: In both groups, the uncorrected distance visual acuity was 0.0 logarithm of the minimum angle of resolution or better in 95% of eyes 3 months postoperatively, and the mean manifest refraction spherical equivalent was within ±1.0 diopter in 90% of eyes. No significant differences were observed between the groups in terms of the uncorrected distance visual acuity or astigmatism. A significant induction of higher order aberrations (HOAs) was observed in both groups. However, the induction of total corneal HOAs (p = 0.014) and spherical aberrations (p < 0.001) was significantly lower in the TG group than that in the WFO group.Conclusions: WFO and TG transPRK effectively improved the visual and refractive outcomes; however, the induction of total corneal HOAs and spherical aberration was lesser following the TG ablation.
Measuring Growth in Ethical Discernment Among Upper-Level Accounting Students: Educational Interventions
Authors: Black William H. , White Barbara S.
Published: June 2024

Effective instruction produces growth in knowledge or movement of perceptions in a desirable direction. Ethics education is emphasized in accounting curricula, but measuring growth or movement is a challenge. The ARBC instrument measures student perceptions of ethical conduct using real-world vignettes. ARBC compared students in Auditing and MAcc classes to students in introductory Finance and Accounting Principles classes, benchmarked against experienced businesspeople and a reference group representing society. Perceptions of Auditing and MAcc students were far more similar to the business panel than the perceptions of the Finance and Principles students, with overall movement in desirable directions.
Museum Governance: Lessons From the Past as a First Step Towards Innovation
Authors: Baillargeon Lisa , Bergeron Yves , Gélinas Patrice
Published: June 2024

Over the past thirty years, private sector governance has seen significant development in regulatory guidelines, best practices, and adaptation to emerging challenges. In contrast, the history of Canadian museum governance is relatively new. Not-for-profit Canadian museums began to establish governance frameworks only recently with influential publications like the UNESCO Recommendation on Museums and Collections (2015) and the SMQ Guide (2014), along with the implementation of Bill 114 in 2016. Bill 114 introduced constraints and responsibilities akin to those in the private sector, shifting governance from a more informal approach to a structured system. Notable examples of pre-Bill 114 governance include Rolland Arpin's initiatives at the Museum of Civilization and guidelines by the Canadian Art Museum Directors Organization. This study aims to explore the lessons that museum governance can learn from private sector practices, comparing regulatory frameworks and drawing insights from corporate governance literature to enhance the sustainability and effectiveness of not-for-profit museums and heritage preservation efforts.
The Influence of COVID-19 on Online Sales in the Wine Sector: A Portuguese Case Study
Authors: Ribau Cláudia , Oliveira Santos Carolina , Figueiredo Joana
Published: June 2024

COVID-19 reinforced the adoption of an online sales strategy, with e-commerce proven to be an asset in achieving positive results. Based on this premise, a case study was developed in the wine sector, to identify a strategic model for the implementation and management of a virtual store. The simultaneous presence of businesses in the largest number of distribution channels is the differentiating factor in the wine sector, as it currently has an extremely attractive market dynamics for its stakeholders. A qualitative methodological case study was developed analyzing the wine sector e-commerce in the context of a theoretical model. The conclusions highlight an increase of online sales in the wine sector in Portugal, and consequently, the importance of creating a virtual store. The growth of the B2C online sales channel indicates there is ‘divergence’ from the traditional offline B2B sales channel. There is resistance by the B2B sales model to adopt online B2C, but despite this, the wine sector favoring e-commerce has seen a boost in sales profits. Pandemic restrictions reduced consumer physical contact which is a limitation of this single case study.
Strength of the Sweep: Exploring the Cleaning Culture of Black Women Consumers
Authors: Powell Kimberly K. , Rey Melanie Powell , Alexander Asia
Published: June 2024

This qualitative research study delves into the rich cleaning culture among Black women consumers, aiming to uncover the underlying motivations, beliefs, and practices that shape their household cleaning behaviors. Through in-depth interviews, the research explores how cultural heritage, community expectations, and personal empowerment inform Black women’s cleaning rituals and product preferences. The study employs a grounded theory approach to analyze participants’ narratives, revealing a complex interplay between societal norms, familial traditions, and individual agency. The findings highlight the role of cleaning as a form of self-expression, a means to preserve cultural legacy, and a powerful avenue for fostering a sense of control and pride within domestic spaces. By illuminating the unique perspectives and experiences of Black women in the realm of domestic cleanliness, this study contributes to a more nuanced understanding of consumer behavior. It offers valuable insights for brands aiming to engage with this community respectfully and authentically.
National Research and Innovation Policy the Case of Greece: A Benchmarking Exercise to Assist Evidence-Based Policies on Research, Innovation, and Technological Entrepreneurship
Authors: Deniozos Dimitris
Published: June 2024

Greece has made considerable effort to develop and implement a concise research and innovation policy during the last decades aiming at a knowledge-intensive economy. New legal frameworks and funding schemes are introduced, funding increased, but evaluation of impact is implemented marginally. The landscape in the early 2020ies has little in common with that in the late 1970ies. The active participation of Greece to the European Union’s framework programs and the European institutions’ prioritization of research and innovation increased the impetus for the policy makers at national level and for an informed policy in this field. Nevertheless, the data are relentless in the demonstration of the effectiveness of the policies. Despite the efforts deployed, Greece continues to lag most European countries, pairing mostly with its neighbors. This proves a strong need for improvement of the efficiency and effectiveness of the policies. It shows that politicians and policy makers are ill prepared to face the new challenges in global competitiveness. Greece is not the only case in this position.
fundamental management journal
Authors: Lumbantoruan Rutman
Published: June 2024

ISSN:2540-9220 (online)
THE ANALYSIS OF CONSUMER SATISFACTION TOWARD GO-PAY FIN-TECH SERVICE AT FACULTY OF ECONOMICS AND BUSINESS STUNDENTS AT CHRISTIAN UNIVERSITY OF INDONESIA
Authors: Sembiring Carolina F. , Tambunan Juniaty
Published: June 2024

The study was conducted at the Faculty of Economics and Business of the Christian University of Indonesia to know customers satisfaction and expectations as well as the implementation or performance of the company. In providing good services to customers, GO-JEK companies must pay attention to the variables that become this research, namely five dimensions of service quality, among others tangiable, responsiveness, assurance, realibility,  and emphaty. GO-JEK management needs to pay attention to comfort and security in every transaction on the GO-PAY application.
 Keywords: Cunstomer satisfaction, The Importance and Performance Analysis, Fin-Tech GO-PAY
MANAGEMENT OVERVIEW: LEADERSHIP IN CHANGE
Authors: Johnson Kennedy Posma Sariguna
Published: June 2024

This paper aims to study how the leadership of an organization manages the process of change in its environment. The challenges faced are various changes both from within and outside the organization in a very fast, chaotic and turbulent, which has become the 'new' normal. The method of writing this paper is done through a study of various literatures. The COVID19 pandemic has various impacts on people's lives, especially business organizations or companies, which has caused many changes in the world of VUCA (Volatility, Uncertainty, Complexity and Ambiguity). Every organization must be able to identify it because every problem requires a fast and precise response. Each of these VUCA components presents challenges that need to be faced with Vision, Understanding, Clarity, and Agility.
 
Keywords: Management, Leadership, Change, VUCA
Presuda prijekomu sucu – sudbina ustaškoga dužnosnika Oktavijana Svježića
Authors: Stipančević Mario
Published: June 2024

Iako se radilo o relativno visokome dužnosniku pravosudnoga i sigurnosnog sustava Nezavisne Države Hrvatske (NDH), sudbina Oktavijana Svježića dosada nije bila cjelovitije zabilježena. Javnosti su bili poznati isključivo oskudni i nepotpuni podatci o njegovu profesionalnome djelovanju, dok se o privatnome životu, uključujući pritom čak i informacije o rođenju i smrti, nije znalo mnogo. U potonje se posebice mogu uključiti i činjenice o njegovu podrijetlu, zbog kojega je – među ostalim – i zaslužio opširniju raspravu. Svježić je još za vrijeme Kraljevine Jugoslavije postao pouzdanim članom proustaških organizacija, održavajući bliske kontakte s istaknutim članovima pokreta, što ga je kao mlada i perspektivna pravnika poguralo u državnu službu odmah po uspostavi endehazijskoga režima. Prvo kao tajnika prvoga povjerenika NDH za Bosnu i Hercegovinu, zatim, u ljeto 1941., kao člana Pokretnoga prijekog suda u Sarajevu te, početkom 1942., namještanja u Ustaškoj nadzornoj službi (UNS). U potonjoj se sastavnici sigurnosnoga aparata istaknuo posredovanjem u nabavci oružja i streljiva za domobranske i ustaške postrojbe prilikom prodora na Drinu u zimu 1941/42., a zatim i u zloglasnoj akciji u Srijemu u ljeto 1942., da bi se nakon istupanja iz službe, djelomičnoga odsluživanja vojnoga roka i rada u očevu privatnome poduzeću u kolovozu 1944. ponovno vratio u državnu službu kao sudac ili predsjednik (prijekih) vojnih sudova u Sarajevu, djelujući na tim pozicijama sve do raspada NDH. Po povlačenju domobranskih i ustaških postrojbi, prvo iz Sarajeva, a nedugo nakon toga i iz Zagreba, razoružan je na jugoslavensko-austrijskoj granici, da bi se zatim potajice odlučio vratiti u rodni grad, u kojemu je ostavio suprugu i roditelje. Uhićenju u svibnju 1947. prethodilo je dvogodišnje skrivanje pred komunističkim vlastima. koje su ga u međuvremenu u odsutnosti osudile na dvadesetogodišnje robijanje zbog počinjenih ratnih zločina. U zatvorima je proveo sljedeće četiri godine, pišući izvještaje o sudjelovanju u ratnim zbivanjima kao i o osobama s kojima je surađivao. Napokon, u postupku pred zagrebačkim Okružnim sudom koncem 1950. osuđen je na smrtnu kaznu te je strijeljan na zagrebačkome Mirogoju u ožujku 1951.
Biografizam u književnopovijesnoj i leksikografskoj metodi Branka Vodnika
Authors: Rogić Musa Tea
Published: June 2024

U radu nastojimo osvijetliti biografsku sastavnicu u opusu Branka Vodnika, s naglaskom na metabiografska i metodološka očitovanja u njegovim književnopovijesnim i kritičkim člancima te u natuknicama u Narodnoj enciklopediji srpsko-hrvatsko-slovenačkoj. Kako bi uvid u Vodnikov leksikografski rad bio potpuniji, konzultirana je i opisana i leksikografska građa u Vodnikovoj rukopisnoj ostavštini. Cilj je rada trojak: osvjetljenje manje poznatih Vodnikovih zapažanja o metodi književnopovijesnoga posla, povezivanje njegovih teza u studijama s interpretacijama koje je donio u natuknicama i opis prijepora u književnopovijesnoj struci koji su se izravno očitovali u Vodnikovu radu i na njegovu profesionalnom putu. Kao istaknut književni povjesničar hrvatske moderne, prepoznat kao metodološki inovator i reformator, recepcijski je bio i precjenjivan kao prvi znanstveni književni povjesničar u nas, ali i stručno osporavan s neknjiževnih pozicija, kao pristran književni stručnjak, čije se ocjene temelje na zagovoru jugoslavenskoga kulturnoga jedinstva. Nastojali smo prenijeti bitne teze koje je sam Vodnik oblikovao kao nosiv dio svoje metode, dio njih i naoko usputno u radovima prigodnoga i polemičkoga značaja, s ciljem nepristrana i vremenski distancirana pogleda na metodološki proturječan, ali izvoran književnopovijesni opus koji je u čitanja hrvatskih pisaca i razumijevanje njihovih duhovnih biografija unio nov, sintetski i genološko-kulturološki pristup, koji je, nedovoljno priznat za Vodnikova života i razumijevan kao znak njegove kritičke ekscentričnosti i metodološke kolebljivosti, puni zamah dobio u radovima suvremenih književnih povjesničara novije književnosti, koji u književnopovijesne sinteze uvrštavaju kulturološke uvide. Vodnik je stoga među pretečama i moderne enciklopedijske književne biografije i kulturološkoga zaokreta u hrvatskoj književnoj povijesti.
A Family of Solutions Related to Shin’s Model For Probability Forecasts
Authors: Kizildemir Melis , Akin Ertugrul , Alkan Altug
Published: June 2024

This work develops a family of solutions related to Shin’s model in producing accurate probability forecasts. More precisely, closed-form solutions are derived based on an analytical approach to known solution and evaluated experimentally for sports betting data sets.
ANALYSIS OF THE EFFECT OF THE NUMBER AND THICKNESS OF PLATES BRASS ON CATALYTIC CONVERTER ON EXHAUST GAS EMISSIONS 100 CC GASOLINE MOTORCYCLE
Authors: Firdaus Ahmad Hanif , Celvin Yoga P Bryan
Published: June 2024

Emisi gas buang adalah polutan yang mencemari udara yang dihasilkan dari gas buang kendaraan. Tujuan dari penelitian ini adalah untuk mengetahui hasil dari pengaruh jumlah dan tebal pelat terhadap emisi gas buang sepeda motor 100 cc, Dan memberikan alternatif penurunan emisi gas buang mengunakan catalytic converter berbahan kuningan dengan harga lebih murah. Untuk mendapatkan data yang sesuai, maka dalam penelitian skripsi ini menggunakan metode penelitian eksperiment. Hasil dari penelitian ini adalah jumlah dan tebal pelat dapat menurunkan emisi CO, dan HC dengan lebih baik. Seperti penggunaan jumlah pelat 5 dan tebal 1 mm menghasilkan gas CO paling rendah yaitu 0,33 g/km pada rpm 3000, sedangkan gas HC yang dihasilkan yaitu 73 ppm pada rpm 3000, ini bisa terjadi karena penyaringan yang dilakukan lebih banyak.
DEVELOPMENT OF MONITORING TOOL SYSTEM FOR ELECTRIC VEHICLE BATTERY ENERGY BASED ON INTERNET OF THINGS
Authors: Wibowo Titho Bafrendy
Published: June 2024

Pengembangan sistem pemantauan Energi baterai untuk kendaraan listrik dikembangkan dengan penambahan fitur berbasis Internet of Things (IoT) dengan DC Wattmeter melalui desain web untuk memonitor nilai energi kendaraan listrik secara jarak jauh yang dapat diakses semua orang, DC Wattmeter ini sebagai pembanding keakuratan pembacaan nilai Wh pada alat pemantau energi baterai. Dalam proses pengujian, menggunakan laptop untuk memantau daya baterai dengan jarak jauh. Tujuan dari penelitian yaitu untuk mengetahui desain sistem alat monitoring energi baterai kendaraan listrik berbasis Internet of Things (IoT). Tujuan lainnya yaitu mengetahui perbedaan pengukuran energi baterai antara alat monitoring tersebut dengan DC Wattmeter.
Metode penelitian menggunakan metode eksperimen, yakni dengan melakukan perbandingan pembacaan nilai energi batarai antara alat monitoring dengan alat DC Wattmeter. Dalam membuktikan kinerja alat monitoring saat melakukan pengukuran energi baterai, dilakukanlah pengujian pada kendaraan listrik dengan jarak tempuh 1 hingga 3 km dan kondisi jalan yang sama. Data yang diperoleh kemudian diolah dan dianalisa menggunakan metode analisa uji-T berpasangan.
Hasil penelitian menunjukkan pengujian yang dilakukan, alat monitoring energi baterai dapat bekerja dengan baik yang ditunjukkan dengan pembacaan nilai energi baterai memiliki perbedaan nilai yang tidak signifikan dengan alat pengukur pita yaitu DC Wattmeter. Hasil analisa menunjukkan nilai P Value (0,15) lebih besar dari 0,05 sehingga hipotesis menyatakan H0 diterima atau tidak ada perbedaan yang signifikan dalam pembacaan nilai energi baterai antara alat monitoring energi baterai berbasis Internet of Things (IoT) dengan DC Wattmeter. Persentase error rata-rata maksimal yaitu 1,69 % .
 
Kata Kunci: Internet of Things (IoT), Kendaraan Listrik, Monitoring
THE ANALYSIS OF PORTING AND POLISHING RESULTS AGAINST MOTORCYCLE TORQUE 150 cm3
Authors: Rizky Fajar Ananda
Published: June 2024

The purpose of this study is to investigate the torque results on standard and modified vehicles, presenting torque comparison graphs for standard and modified motorcycle engines. The experimental study used a 150cm3 motorcycle, analyzing the experimental results directly. The study shows the difference in performance, especially torque, across all engine variations at every 500rpm. The study involved porting and polishing modifications to increase engine torque, resulting in a 4.8% increase in torque over standard. The modifications widened the torque range, providing improved performance across a wide range of speeds. The modified motorcycle exhibited faster acceleration, navigating the terrain and heavy traffic with ease. Improved performance at high speeds, stability and temperature maintenance were observed. The porting and polishing modifications had a positive impact on engine torque throughout 6500 to 9000rpm, with 6500 rpm porting A and polishing B displaying optimal results, achieving 14.4Nm of torque, an increase of 0.8Nm over standard conditions.
Penguatan Kinerja Keuangan UKM melalui Aset Tidak Berwujud dan Strategi Bersaing
Authors: Dilasari Aranta Prista , Mahmudah Annita , Hakim Mesra Berlyn
Published: June 2024

Abstract: Strengthening SME Financial Performance through Intangible Assets and Competitive StrategiesPurpose: the purpose of the article should be concise and presented in one sentence.Method: data was obtained from a questionnaire and processed with WarpPLS software.Results: Intangible Assets have a positive and significant effect on the financial performance of SMEs, competitive strategy also acts as a moderator of Intangible Assets on the financial performance of SMEs in the Mangrove batik industry in Surabaya.Novelty: competitive strategy can strengthen the relationship between intangible assets and financial performance.Contribution: Provide justification for the importance of invention for SMEs that can strengthen financial performance.
Abstrak: Penguatan Kinerja Keuangan UKM melalui Aset Tidak Berwujud dan Strategi BersaingTujuan: untuk menguji dan menganalisis pengaruh Aset Tak Berwujud terhadap Kinerja Keuangan UKM, serta menguji apakah strategi bersaing moderasi berpengaruh terhadap Aset Tak Berwujud terhadap kinerja keuangan UKM Batik Mangrove di Surabaya.Metode: data diperoleh dari kuesioner dan diolah dengan software WarpPLSHasil: Aset Tak Berwujud berpengaruh positiff dan signifikan terhadap kinerja keuangan UKM, strategi bersaing juga berperan sebagai moderator Aset Tidak Berwujud dengan kinerja keuangan UKM pada industri batik Mangrove di Surabaya.Kebaruan: Strategi bersaing dapat memperkuat hubunan antara intangible asset dengan financial performance. Kontribusi: Memberikan justifikasi pentingnya invensi pada UKM yang dapat memperkuat kinerja keuangan
Signifikansi Penetapan Calon Presiden Indonesia 2024 pada Volume Perdagangan Saham
Authors: Safira Shobiro Elsa , Ekasari Kurnia , Winarto Edi
Published: June 2024

Abstract: The Significance of Determining the 2024 Indonesian Presidential Candidates on Stock Trading VolumePurpose: examining the effect of the announcement of Anies Baswedan and Ganjar Pranowo as presidential candidates on the level of Abnormal Return and trading volume activity of stocks listed in the LQ-45 Index on the Indonesia Stock Exchange (IDX).Method: Using a quantitative event study methodology with secondary sources dataResults: The results showed that there was no statistically significant difference in Abnormal Return before and after the announcement event of the two presidential candidates.Novelty: this research seeks to explain the above phenomenon, with an observation period of 14 days. Contribution: this research could be used by investors in investment strategy regarding stock
Abstrak: Signifikansi Penentuan Calon Presiden Indonesia 2024 Terhadap Volume Perdagangan SahamTujuan: menguji pengaruh pengumuman Anies Baswedan dan Ganjar Pranowo sebagai calon presiden terhadap tingkat Abnormal Return dan aktivitas volume perdagangan saham-saham yang terdaftar dalam Indeks LQ-45 di Bursa Efek Indonesia (BEI).Metode: Menggunakan metodologi event study kuantitatif dengan sumber data sekunderHasil: Hasil penelitian menunjukkan bahwa tidak terdapat perbedaan Abnormal Return yang signifikan secara statistik sebelum dan sesudah acara pengumuman kedua calon presiden.Kebaruan: Penelitian ini berupaya menjelaskan fenomena di atas, dengan periode pengamatan selama 14 hari.Kontribusi: penelitian ini dapat digunakan oleh investor dalam strategi investasi di bidang saham.
Perlakuan Akuntansi untuk Jagung
Authors: Zuhdi Rahmat , Zulfatillah Auliya , Viraninur Febriana Inggrit , Badriyah
Published: June 2024

Abstract: Accounting Treatment for Corn
Purpose: reveal the accounting treatment of corn in the form of definition, recognition, measurement, assessment, presentation and disclosure of corn accounting
Method: This research method uses phenomenology through data collection by interviews, observation and documentation
Results: Accounting recognition of corn is more appropriately recognized as inventory and its measurement is based on costs from planting to harvest. The valuation is based on the selling price minus costs and is presented in the form of a simple note. Corn accounting is more appropriately expressed based on Statement of Financial Accounting Standards 14 concerning inventory accounting.
Novelty: discusses the accounting treatment of corn from the aspect of financial accounting standards
Contribution: This research is for policies related to simple recording practices for farmers so they can see the profits and losses they make when farming.
 
Abstrak: Perlakuan Akuntansi untuk Jagung
 
Tujuan: mengungkap perlakuan akuntansi jagung berupa definisi, pengakuan, pengukuran, penilaian, penyajian dan pengungkapan akuntansi jagung
Metode: metode penelitian ini menggunakan fenomenologi melalui pengumpulan data dengan wawancara, obeservasi dan dokumentasi
Hasil: Pengakuan akuntansi jagung lebih tepat diakui sebagai persediaan dan pengukurannya berdasarkan biaya mulai menanam sampai panen. Penilaian didasarkan atas harga jual dikurangi dengan biaya-biaya dan disajikan dalam bentuk catatan yang sederhana. Akuntansi jagung lebih tepat diungkapkan berdasarkan Pernyataan Standar Akuntansi Keuangan 14 tentang akuntansi persediaan.
Kebaruan: membahas perlakuan akuntansi jagung dari aspek standar akuntansi keuangan
Kontribusi: kebijakan terkait praktik pencatatan sederhana bagi pelaku petani agar dapat melihat keuntungan dan kerugian yang diperoleh saat bertani.
Maksimalisasi Profit UMKM Berdasarkan Perspektif Pricing Strategy
Authors: Odang Nilam Kemala , Sidabutar Gaby Ruminsah Arnita
Published: June 2024

Abstract: SMSE Profit Maximization Based on Pricing Strategy PerspectivePurpose: this study aims to maximize SMSE profits analyzed by pricing strategy perspective.Method: qualitative descriptive methods with case study approaches. Results: business owner needs to set different profits between manufactured and merchandise goods in order to maximize their profit. However, there are several additional scenarios for MSME to carry out better profit planning.Novelty: the study presents a profit planning based on pricing strategy approach which is expected to help MSME maximize the profits they will earn.Contribution: to help MSMEs to achieve profit maximization so that MSMEs can continue to do business and expand.
Abstrak: Maksimalisasi Laba UMKM Berdasarkan Perspektif Pricing StrategyTujuan: menggambarkan strategi penetapan harga jual dan perencanaan laba pada tingkat harga yang berbeda.Metode: metode analisis data menggunakan metode deskriptif kualitatif dengan menggunakan cost-plus pricing dan cost-volume-profit sebagai alat ukurnya.Hasil: berdasarkan struktur biaya pada periode ini, harga jual yang paling ideal adalah harga jual yang menetapkan laba sebesar 25% dan 15%. Di samping itu, perencanaan laba UMKM berada pada kondisi yang baik.Kebaruan: : penelitian menyajikan hasil analisis penetapan harga jual dan perencanaan laba yang dapat membantu UMKM dalam menyusun strategi.Kontribusi: membantu UMKM dalam penyusunan strategi terkait harga jual dan perencanaan laba.
Menilik Reaksi Pasar Terhadap Pengumuman Rilis Fatwa MUI No. 83 Tahun 2023
Authors: Gunibala Zakir , Renuat Andini , Dzikriah Sukmawati Indah
Published: June 2024

Abstract: Examining the Market Reaction to the Announcement of the Release of MUI Fatwa No. 83 Year 2023Purpose: Revealing the market reaction that has an impact on the stimulus in the form of MUI's fatwa on the appeal not to use Israeli-affiliated products released in November 2023.Method: Quantitative method of case study approach. Using statistical analysis of 14 samples of companies listed on the IDX. Data obtained from the IDX and Yahoo Finance pages.Results: Shows that there is no AR and no significant difference during the event period studied. TVA shows significant statistical analysis results.Novelty: The current issue raised, which is related to the announcement of MUI fatwa no. 83 of 2023 concerning the appeal not to use products affiliated with Israel.Contribution: Expand the literature of market reaction studies with the latest relevant issues.nouncement of MUI fatwa no. 83 of 2023 concerning the appeal not to use products affiliated with Israel.
Abstrak: Menilik Reaksi Pasar Terhadap Pengumuman Rilis Fatwa MUI No. 83 Tahun 2023Tujuan: Mengungkap reaksi pasar yang berdampak pada stimulus berupa penerbitan fatwa oleh MUI tentang imbauan menghindari produk terafiliasi Israel pada November 2023.Metode: Metode kuantitatif pendekatan studi kasus menggunakan analisis statistik terhadap 14 sampel perusahaan yang diperoleh dari laman BEI dan Yahoo Finance.Hasil: Mengungkapkan tidak adanya AR serta tidak ada signifikansi perbedaan selama Jendela Peristiwa yang diobservasi. TVA menunjukkan hasil analisis statistik yang signifikan.Kebaruan: terletak pada isu yang diangkat saat ini, yaitu terkait dengan pengumuman fatwa MUI no. 83 tahun 2023 tentang himbauan untuk tidak menggunakan produk yang berafiliasi dengan Israel.Kontribusi: Memperluas literatur kajian reaksi pasar dengan isu terbaru yang relevan.
Characterization of the effects of cannabinoid receptor deletion on energy metabolism in female C57BL mice
Authors: Sotzen Morgan , Ahmed Ahmed , Olson L. Karl , Alshaarawy Omayma
Published: June 2024

Background

Despite the evidence that energy balance is regulated differently in females and that the endocannabinoid system is sexually dimorphic, previous studies on the endocannabinoid system and energy balance predominantly used male models. Here, we characterize the effects of cannabinoid receptor deletion on body weight gain and glucose metabolism in female C57BL mice.

Methods

Female mice lacking the cannabinoid-1 receptor (CB1R-/-), cannabinoid-2 receptor (CB2R-/-), or both receptors (CB1R-/-/CB2R-/-) and wild-type (WT) mice were fed with a low (LFD; 10% of calories from fat) or high-fat diet (HFD; 45% of calories from fat) for six weeks.

Results

Female WT mice fed with HFD gained significantly more weight than WT mice fed with LFD (p < 0.001). Similar pattern was observed for CB2/- mice fed with HFD compared to CB2R-/- mice fed with LFD (p < 0.001), but not for CB1R-/- fed with HFD vs. LFD (p = 0.22) or CB1R-/-/CB2R-/- fed with HFD vs. LFD (p = 0.96). Comparing the 4 groups on LFD, weight gain of CB1R-/- mice was greater than all other genotypes (p < 0.05). When fed with HFD, the deletion of CB1R alone in females did not attenuate weight gain compared to WT mice (p = 0.72). Female CB1R-/-/CB2R-/- mice gained less weight than WT mice when fed with HFD (p = 0.007) despite similar food intake and locomotor activity, potentially owing to enhanced thermogenesis in the white adipose tissue. No significant difference in weight gain was observed for female CB2R-/- and WT mice on LFD or HFD. Fasting glucose, however, was higher in CB2R-/- mice fed with LFD than all other groups (p < 0.05).

Conclusion

The effects of cannabinoid receptor deletion on glucose metabolism in female mice were similar to previously published findings on male mice, yet the effects on body weight gain and thermogenesis were attenuated in CB1R-/- mice.
Bridging the gap: exploring the causal relationship between metformin and tumors
Authors: Zhang Zexin , Wu Wenfeng , Wu Zexia , He Yihan , Chang Xuesong , Deng Shenyuan , Zhou Rui , Chen Yadong , Zhang Haibo
Published: June 2024

Objective

Numerous studies have reported that metformin can reduce the risk of tumor development. However, some of the results of these studies are conflicting, necessitating a more reliable evaluation.

Methods

We conducted a Mendelian randomization phenome-wide association study (MR-PheWAS) of tumors to explore the causal relationship between metformin and tumors. Two cohorts of patients taking metformin were obtained from the UK Biobank. Complete phenotype data of the tumors were obtained from FinnGen_R10. We elucidated the causal relationship using a two-sample Mendelian randomization (MR) analysis. More importantly, we conducted a meta-analysis to ensure relatively unbiased results. In the MR analysis, we used the inverse-variance weighted (IVW) method as the main outcome indicator. Subsequently, two cohorts were integrated for the meta-analysis. Finally, we investigated the mechanisms through mediational MR analysis.

Results

MR analysis revealed that metformin might have a causal relationship with 13 tumor-associated phenotypes in the training cohort. Four phenotypes were validated in the testing cohort. In the training and testing cohorts, metformin exhibited a protective effect against brain meningiomas and malignant neoplasms of the breast (HER-positive), oral cavity, tonsils, and the base of the tongue. Intriguingly, after integrating the results of the two cohorts for the meta-analysis, 12 results were statistically significant. Mediational MR analysis suggested that the effects of metformin on brain meningiomas may be weakened by the presence of the family Oxalobacteraceae.

Conclusion

Metformin exhibits potential preventive and therapeutic effects on four types of tumors: brain meningioma, malignant neoplasms of the breast (HER-positive), oral cavity and tonsils, and the base of the tongue. Large randomized controlled trials are required to confirm these findings.
IL-10 predicts incident neuroinflammatory disease and proviral load dynamics in a large Brazilian cohort of people living with human T-lymphotropic virus type 1
Authors: Assone Tatiane , Menezes Soraya Maria , Gonçalves Fernanda de Toledo , Folgosi Victor Angelo , Braz Marcos , Smid Jerusa , Haziot Michel E. , Marcusso Rosa M. N. , Dahy Flávia E. , de Oliveira Augusto César Penalva , Vanderlinden Evelien , Claes Sandra , Daelemans Dirk , Vercauteren Jurgen , Schols Dominique , Casseb Jorge , Van Weyenbergh Johan
Published: June 2024

Human T-Lymphotropic Virus type-1 (HTLV-1) is a unique retrovirus associated with both leukemogenesis and a specific neuroinflammatory condition known as HTLV-1-Associated Myelopathy (HAM). Currently, most proposed HAM biomarkers require invasive CSF sampling, which is not suitable for large cohorts or repeated prospective screening. To identify non-invasive biomarkers for incident HAM in a large Brazilian cohort of PLwHTLV-1 (n=615 with 6,673 person-years of clinical follow-up), we selected all plasma samples available at the time of entry in the cohort (between 1997–2019), in which up to 43 cytokines/chemokines and immune mediators were measured. Thus, we selected 110 People Living with HTLV-1 (PLwHTLV-1), of which 68 were neurologically asymptomatic (AS) at baseline and 42 HAM patients. Nine incident HAM cases were identified among 68 AS during follow-up. Using multivariate logistic regression, we found that lower IL-10, IL-4 and female sex were independent predictors of clinical progression to definite HAM (AUROC 0.91), and outperformed previously suggested biomarkers age, sex and proviral load (AUROC 0.77). Moreover, baseline IL-10 significantly predicted proviral load dynamics at follow-up in all PLwHTLV-1. In an exploratory analysis, we identified additional plasma biomarkers which were able to discriminate iHAM from either AS (IL6Rα, IL-27) or HAM (IL-29/IFN-λ1, Osteopontin, and TNFR2). In conclusion, female sex and low anti-inflammatory IL-10 and IL-4 are independent risk factors for incident HAM in PLwHTLV-1,while proviral load is not, in agreement with IL-10 being upstream of proviral load dynamics. Additional candidate biomarkers IL-29/IL-6R/TNFR2 represent plausible therapeutic targets for future clinical trials in HAM patients.
Soil organic matter and water content affect the community characteristics of arbuscular mycorrhizal fungi in Helan mountain, an arid desert grassland area in China
Authors: Shao Leilei , Yan Peixuan , Ye Siqi , Bai Hao , Zhang Rui , Shi Guangyao , Hu Yang , Pang Danbo , Niu Xiang , Ni Xilu
Published: June 2024

Introduction

Arbuscular mycorrhizal fungi (AMF) are vital in terrestrial ecosystems. However, the community structure characteristics and influencing factors of AMF in the forest ecosystems of arid desert grassland areas require further investigation.

Methods

Therefore, we employed high-throughput sequencing technology to analyze the soil AMF community characteristics at different elevations in the Helan mountains.

Results

The results revealed that significant differences (P < 0.05) were observed in the soil physicochemical properties among different elevations, and these properties exhibited distinct trends with increasing elevation. Through high-throughput sequencing, we identified 986 operational taxonomic units (OTUs) belonging to 1 phylum, 4 classes, 6 orders, 12 families, 14 genera, and 114 species. The dominant genus was Glomus. Furthermore, significant differences (P < 0.05) were observed in the α-diversity of the soil AMF community across different elevations. Person correlation analysis, redundancy analysis (RDA), and Monte Carlo tests demonstrated significant correlations between the diversity and abundance of AMF communities with soil organic matter (OM) (P < 0.01) and soil water content (WC) (P < 0.05).

Discussion

This study provides insights into the structural characteristics of soil AMF communities at various altitudes on the eastern slope of Helan mountain and their relationships with soil physicochemical properties. The findings contribute to our understanding of the distribution pattern of soil AMF and its associations with environmental factors in the Helan mountains, as well as the stability of forest ecosystems in arid desert grassland areas.
Contrasting effects of NADPH oxidases on the fungal hyphae growth and immune responses in Pleurotus ostreatus
Authors: Li Huiping , Zhu Jiachun , Li Zihao , Xu Ping , Ma Lin , Zou Yajie , Qu Shaoxuan , Wu Xiaoqin
Published: June 2024

Pleurotus ostreatus is one of the most consumed mushroom species, as it serves as a high-quality food, favors a rich secondary metabolism, and has remarkable adaptability to the environment and predators. In this study, we investigated the function of two key reactive oxygen species producing enzyme NADPH oxidase (PoNoxA and PoNoxB) in P. ostreatus hyphae growth, metabolite production, signaling pathway activation, and immune responses to different stresses. Characterization of the Nox mutants showed that PoNoxB played an important role in the hyphal formation of the multicellular structure, while PoNoxA regulated apical dominance. The ability of P. ostreatus to tolerate a series of abiotic stress conditions (e.g., osmotic, oxidative, membrane, and cell-wall stresses) and mechanical damage repair was enhanced with PoNoxA over-expression. PoNoxB had a greater responsibility in regulating the polysaccharide composition of the cell wall and methyl jasmonate and gibberellin GA1 biosynthesis, and improved mushroom resistance against Tyrophagus putrescentiae. Moreover, mutants were involved in the jasmonate and GA signaling pathway, and toxic protein defense metabolite production. Our findings shed light on how the oyster mushroom senses stress signals and responds to adverse environments by the complex regulators of Noxs.
Current state of clinical ultrasound neuromodulation
Authors: Matt Eva , Radjenovic Sonja , Mitterwallner Michael , Beisteiner Roland
Published: June 2024

Unmatched by other non-invasive brain stimulation techniques, transcranial ultrasound (TUS) offers highly focal stimulation not only on the cortical surface but also in deep brain structures. These unique attributes are invaluable in both basic and clinical research and might open new avenues for treating neurological and psychiatric diseases. Here, we provide a concise overview of the expanding volume of clinical investigations in recent years and upcoming research initiatives concerning focused ultrasound neuromodulation. Currently, clinical TUS research addresses a variety of neuropsychiatric conditions, such as pain, dementia, movement disorders, psychiatric conditions, epilepsy, disorders of consciousness, and developmental disorders. As demonstrated in sham-controlled randomized studies, TUS neuromodulation improved cognitive functions and mood, and alleviated symptoms in schizophrenia and autism. Further, preliminary uncontrolled evidence suggests relieved anxiety, enhanced motor functions in movement disorders, reduced epileptic seizure frequency, improved responsiveness in patients with minimally conscious state, as well as pain reduction after neuromodulatory TUS. While constrained by the relatively modest number of investigations, primarily consisting of uncontrolled feasibility trials with small sample sizes, TUS holds encouraging prospects for treating neuropsychiatric disorders. Larger sham-controlled randomized trials, alongside further basic research into the mechanisms of action and optimal sonication parameters, are inevitably needed to unfold the full potential of TUS neuromodulation.
Small bowel adenocarcinoma of the jejunum detected by double contrast enhanced ultrasound: a case report of a novel ultrasound modality
Authors: Wu Shuang , Yu Huizhen , Liu Ying , Zhou Hong , Zhou Yang
Published: June 2024

Background

Small Bowel Adenocarcinoma (SBA) is rare, occult and life-threatening malignancy in digestive system. Given low incidence and nonspecific symptoms, SBA is frequently detected in later stages. Double contrast enhanced ultrasound (DCEUS) is an innovative imaging technique applied to visualize the gastrointestinal tract, merging intravenous contrast-enhanced ultrasound with oral contrast-enhanced ultrasound. In this case, DCEUS was utilized and successfully detected an SBA of the jejunum.

Case presentation

A Chinese woman, aged 64, sought consultation in the gastroenterology department at our hospital, reporting symptoms of abdominal pain. Three months before entering the hospital, she underwent gastroscopy and colonoscopy which suggested chronic gastritis, and she was treated with oral drugs. However, her symptoms were not relieved, and even worsened. To further investigate, DCEUS was performed. The oral contrast agent dilated the luminal space of the upper gastrointestinal tract, resolving the hindrance caused by gas in the gastrointestinal tract and creating an acoustic window for scanning. Through this acoustic window, oral agent contrast-enhanced ultrasound (OA-CEUS) revealed a localized thickening of jejunal intestinal wall measuring 4x3 cm. Following intravenous injection of ultrasound contrast agent, the jejunal lesion exhibited faster enhancement and heterogeneous hyper-enhancement. Finally, the patient underwent jejunal tumor resection. Pathological examination revealed a jejunal adenocarcinoma.

Conclusion

The timely diagnosis of SBA can be challenging. DCEUS may have the potential to contribute to diagnosis and detailed evaluation of SBA, particularly in cases involving jejunum. Further researches are needed to fully explore the benefits of DCEUS in the standard diagnostic approach for small bowel diseases.
Harnessing adrenergic blockade in stress-promoted TNBC in vitro and solid tumor in vivo: disrupting HIF-1α and GSK-3β/β-catenin driven resistance to doxorubicin
Authors: Attia Yasmeen , Hakeem Andrew , Samir Rawda , Mohammed Aya , Elsayed Abdullrahman , Khallaf Alaa , Essam Eman , Amin Hossameldeen , Abdullah Sarah , Hikmat Salwan , Hossam Tarek , Mohamed Ziad , Aboelmagd Ziad , Hammam Olfat
Published: June 2024

Sympathetic activation triggered by chronic stress afflicting cancer survivors is an emerging modulator of tumorigenesis. Adrenergic blockade was previously associated with improving response to doxorubicin (DOX) in triple-negative breast cancer (TNBC), yet the precise underlying mechanisms remain obscure. The resilience of cancer stem cells (CSCs) during chemotherapy fosters resistance and relapse. Hypoxia-inducible factor-1α (HIF-1α) and β-catenin are intertwined transcriptional factors that enrich CSCs and evidence suggests that their expression could be modulated by systemic adrenergic signals. Herein, we aimed to explore the impact of adrenoreceptor blockade using carvedilol (CAR) on DOX and its potential to modulate CSCs overcoming chemoresistance. To achieve this aim, in vitro studies were conducted using adrenaline-preincubated MDA-MB-231 cells and in vivo studies using a chronic restraint stress-promoted solid tumor mouse model. Results revealed that adrenaline increased TNBC proliferation and induced a phenotypic switch reminiscent of CSCs, as evidenced by enhanced mammosphere formation. These results paralleled an increase in aldehyde dehydrogenase-1 (ALDH-1) and Nanog expression levels as well as HIF-1α and β-catenin upsurge. In vivo, larger tumor volumes were observed in mice under chronic stress compared to their unstressed counterparts. Adrenergic blockade using CAR, however, enhanced the impact DOX had on halting TNBC cell proliferation and tumor growth via enhanced apoptosis. CAR also curbed HIF-1α and β-catenin tumor levels subsequently suppressing ALDH-1 and SOX2. Our study unveils a central role for HIF-1α linking stress-induced sympathetic activation fueling CSC enrichment via the β-catenin pathway. It also highlights novel insights into CAR’s capacity in reversing DOX chemoresistance in TNBC.