bluuebunny/crossref_metadata_2025 huggingface dataset:
Drip irrigation and sulphur fertilization influenced fodder yield, quality and water use efficiency of groundnut in arid region
Authors: Gautam Priyanka , Bhunia S. R. , Sahoo A. , Sawal R. K. , Rakshit Shantanu , Yadav V. K. , Lal B. , Ramniwas  , Gograj  , Bishnoi Rajesh , Rathore V. S.
Published: August 2023

Availability of ample and nutritious fodder for livestock is always a challenge in arid region. Choice of crops such as groundnut that can fulfil the requirement of fodder with its crop residues along with human needs can be a viable option to bridge the gap between availability and requirement of fodder. The fodder yield and quality largely depend on soil moisture and nutrient supply especially sulphur (S), a key nutrient for improving groundnut fodder quality. However, no researchers have given emphasis on coupling effect of drip irrigation (DI) and sulphur on fodder yield, quality, digestibility and water use efficiency (WUE). Therefore, the study was conducted to determine the effects of different regimes of DI and S on productivity and quality of fodder. Results revealed that higher regimes of DI i.e. 0.8 +1.0 PE(pan evaporation) and 1.0 PE level of irrigation along with 40 kg S ha-1significantly improved the yield, primary quality traits (crude protein, ether extract and ash), digestibility indices and significant reduction in Fibers which indicates improvement in quality of fodder. Fodder productivity was 27.0 and 25.6% higher in 1.0 PE and 0.8+1.0 PE level of irrigation, respectively, as compared to 0.6 PE level (lower water regime) of irrigation, although 0.6 PE level of irrigation recorded higher WUE and was at par with 0.8 PE and 0.6 +1.0 PE level of DI. By changing the levels of DI from 1.0 PE to 0.8+1.0 PE, considerable water can be saved without affecting the yield and quality of fodder. Similarly, crop responded to S up to 60 kg ha-1but at par with 40 kg S ha-1indicating that application of extra S after 40 kg did not warrant any extra benefit in terms of fodder yield, WUE and quality of fodder. Thus, adjusting the PE levels of DI for water saving and optimal S application can be a sustainable strategy to improve the productivity and quality of groundnut fodder in arid region.
In silico analysis and experimental validation shows negative correlation between miR-1183 and cell cycle progression gene 1 expression in colorectal cancer
Authors: Fatima Syeda Alina , Nasim Mubeen Tabish , Malik Ambrin , Rehman Saif Ur , Waris Saboora , Rauf Manal , Ali Syed Salman , Haq Farhan , Awan Hassaan Mehboob
Published: August 2023

MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate gene expression by binding to the 3’ untranslated regions (UTR) of target genes. Aberrant expression of miRNAs can lead to disease, including cancer. Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Among several factors, differential expression of miRNA can have serious consequences on disease progression. This study was designed to computationally identify and experimentally verify strong miRNA candidates that could influence CRC progression. In silico analysis of publicly available gene expression microarray datasets revealed significant upregulation of miR-1183 in CRC. Comparison of mRNA microarray expression data with predicted miR-1183 targets led to the identification of cell cycle progression gene 1 (CCPG1) as strong, negatively correlated miR-1183 target. Expression analysis by means of quantitative PCR validated the inverse correlation between miR-1183 and CCPG1 in colorectal cancer tissues. CCPG1 indirectly modulates the cell cycle by interacting with the PH/DH domain of Dbs (Rho-specific guanine nucleotide exchange factor). Interestingly, the computational analysis also showed that miR-1183 is upregulated in liver and gastric cancer. This finding is notable as the liver and stomach are the primary metastatic sites for colorectal cancer and hepatocellular carcinoma respectively. This novel finding highlights the broader implications of miR-1183 dysregulation beyond primary CRC, potentially serving as a valuable prognostic marker and a therapeutic target for both primary and metastatic CRC.
Two opposing gene expression patterns within ATRX aberrant neuroblastoma
Authors: van Gerven Michael R. , Schild Linda , van Arkel Jennemiek , Koopmans Bianca , Broeils Luuk A. , Meijs Loes A. M. , van Oosterhout Romy , van Noesel Max M. , Koster Jan , van Hooff Sander R. , Molenaar Jan J. , van den Boogaard Marlinde L.
Published: August 2023

Neuroblastoma is the most common extracranial solid tumor in children. A subgroup of high-risk patients is characterized by aberrations in the chromatin remodeller ATRX that is encoded by 35 exons. In contrast to other pediatric cancer where ATRX point mutations are most frequent, multi-exon deletions (MEDs) are the most frequent type of ATRX aberrations in neuroblastoma. 75% of these MEDs are predicted to produce in-frame fusion proteins, suggesting a potential gain-of-function effect compared to nonsense mutations. For neuroblastoma there are only a few patient-derived ATRX aberrant models. Therefore, we created isogenic ATRX aberrant models using CRISPR-Cas9 in several neuroblastoma cell lines and one tumoroid and performed total RNA-sequencing on these and the patient-derived models. Gene set enrichment analysis (GSEA) showed decreased expression of genes related to both ribosome biogenesis and several metabolic processes in our isogenic ATRX exon 2–10 MED model systems, the patient-derived MED models and in tumor data containing two patients with an ATRX exon 2–10 MED. In sharp contrast, these same processes showed an increased expression in our isogenic ATRX knock-out and exon 2–13 MED models. Our validations confirmed a role of ATRX in the regulation of ribosome homeostasis. The two distinct molecular expression patterns within ATRX aberrant neuroblastomas that we identified imply that there might be a need for distinct treatment regimens.
The prevalence of pediatric asthma hospitalizations at different stages of the COVID-19 pandemic: A systematic review and meta-analysis study protocol
Authors: Abdelrahim Reem , Gao Zhiwei , Smith Mary Jane , Newhook Leigh Anne
Published: August 2023

Background

Asthma is a highly prevalent chronic inflammatory lung disease and is a frequent cause of hospitalization in children. The COVID-19 pandemic has introduced several challenges that have impacted the delivery of care for vulnerable patients, including asthmatic children. Asthmatic children without immediate access to healthcare services can face severe and fatal consequences. Furthermore, various governmental restrictions and viral mutants have been introduced throughout the pandemic, affecting COVID-19 cases and hospitalization rates.

Objectives

To investigate the impact of the COVID-19 pandemic on the prevalence of asthma hospitalizations during various stages of the pandemic. We also aim to compare asthma hospital admissions during the pandemic to pre-pandemic periods.

Methods and analysis

The databases PubMed (MEDLINE), EMBASE, CINAHL, and the Cochrane library will be used to identify relevant articles between the start of the pandemic and the date of the search strategy. Studies will be included if they examine hospital admissions for pediatric (0 to 18 years) asthma patients, regardless of asthma severity, sex, ethnicity or race. Observational retrospective cohort, prospective cohort, and cross-sectional studies will be included. A meta-analysis will be conducted if there are ≥2 articles. Else, a narrative review will be used to report our results.

Trial registration

PROSPERO registration number:CRD42022337606.
Which aspects of job determine satisfaction among pharmacists working in Saudi pharmacy settings?
Authors: Islam Md. Ashraful , Naqvi Atta Abbas
Published: August 2023

Objective

The aim of this study was to evaluate the impact of several employment-related aspects on overall job satisfaction among pharmacists working in Saudi pharmacy settings.

Methods

A cross-sectional survey was conducted for a period of 1-month (December 2020) among pharmacists working in community pharmacies located in 3 cities of Saudi Arabia. Convenience sampling was employed, and the data was collected using the English version of Job Satisfaction Survey (JSS) questionnaire. The data was analyzed using IBM SPSS version 23. Descriptive statistics such as mean (x¯) and 95% confidence interval range were used to report continuous data; frequency (%) and sample counts (N) were used to report categorical data. Bivariate analyses were conducted using chi square (χ2) test. A multiple linear regression model was formulated to report the employment aspects that determined overall job satisfaction of pharmacists. The study was approved by an ethics committee.

Results

A total of 241 samples were analyzed. Less than a quarter of pharmacists (N = 54, 22.4%) were satisfied with their job. The overall job satisfaction score was 130.74 out of 199. The sub-scales for co-workers and communication had scores > 15.8 out of 24; subscale for operating conditions had score > 12.5 out of 20. The subscales for promotion and rewards had scores < 14 out of 24. The aspects of communication, fringe benefits and nature of work had the highest contribution towards overall job satisfaction. For a unit increase in score for communication, fringe benefits, and nature of work, the overall job satisfaction score increased by 0.204, 0.2, and 0.199, respectively.

Conclusion

A very small number of pharmacists seemed satisfied with their job. Satisfaction with communication, nature of work and fringe benefits contributed the most toward overall job satisfaction. Results of this study could provide the means for human resource managers and organizational policy makers to delve into the determinants of satisfaction among pharmacists working in community settings.
Warming and Wetting will continue over the Tibetan Plateau in the Shared Socioeconomic Pathways
Authors: Deng Hao , Ji Zhenming
Published: August 2023

We have used bias-corrected data from CMIP6 models to drive a regional climate model and project climate on the Tibetan Plateau (TP) in the 21st century. Changes in two background fields, namely, 2-meter air temperature and total precipitation, were analyzed. The results show that the WRF simulations capture the terrain effect that cannot be represented in low-resolution models. The simulation of temperature is better in summer than in winter, while the simulated precipitation is the opposite. By the end of the 21st century, the entire TP region experiences significant warming, with an average warming of 3°C and 7°C in the SSP245 and SSP585 scenarios, respectively. The western region shows a greater warming amplitude, with a maximum of more than 10°C in the SSP585 scenario. Most regions of the TP had significant increases in precipitation by the end of the 21st century, with precipitation increasing by 90 mm and 200 mm in the two scenarios, respectively. However, in the low-altitude areas of southeastern TP, total winter precipitation is significantly reduced in the SSP585 scenario. The strengthening of the East Asian summer monsoon and westerly disturbances collectively leads to a significant increase in precipitation within the TP region. By the end of the 21st century, the average annual precipitation in the TP is projected to reach approximately 600 millimeters.
Using ecotourism boats for estimating the abundance of a bottlenose dolphin population in south-eastern Australia
Authors: Lacetera Paola , Mason Suzanne J. , Tixier Paul , Arnould John P. Y.
Published: August 2023

It is challenging to collect robust, long-term datasets to properly monitor the viability and social structure of large, long-lived animals, especially marine mammals. The present study used a unique long-term dataset to investigate the population parameters and social structure of a poorly studied population of bottlenose dolphins (Tursiops sp.) in southern Port Phillip Bay, south-eastern Australia. Photo-identification images have been collected between 2012–2022 both opportunistically and following a protocol by patrons, staff, and volunteers of ecotourism companies using their vessels as platforms. The resulting large dataset was available to be processed through the online platform Flukebook and used in capture recapture models to estimate abundance and demographic parameters. In addition, the social structure of the population and the reproductive parameters were investigated. The marked adult population abundance (45.2 ± 2.7 individuals) was found to be stable over the last decade and the calving rate ranged between 0.06–0.19 new calves per identified individuals per year, while the inter-birth interval was 3.7 ± 0.8 years. Social analysis suggested the population has a fission-fusion structure with no apparent clusters. The stability of the population over the study period suggests no deleterious effect of anthropogenic or environmental factors during the last decade. This study is the outcome of the effort of the ecotourism organisations and the results obtained, along with their similarity to those of other dolphin populations worldwide, highlight the importance of such data sources for long-term information that would otherwise be too expensive or logistically difficult to obtain.
COVID-19 resilience index in European Union countries based on their risk and readiness scale
Authors: Aboelnaga Somaya , Czech Katarzyna , Wielechowski Michał , Kotyza Pavel , Smutka Lubos , Ndue Kennedy
Published: August 2023

Addressing risks and pandemics at a country level is a complex task that requires transdisciplinary approaches. The paper aims to identify groups of the European Union countries characterized by a similar COVID-19 Resilience Index (CRI). Developed in the paper CRI index reflects the countries’ COVID-19 risk and their readiness for a crisis situation, including a pandemic. Moreover, the study detects the factors that significantly differentiate the distinguished groups. According to our research, Bulgaria, Hungary, Malta, and Poland have the lowest COVID-19 Resilience Index score, with Croatia, Greece, Czechia, and Slovakia following close. At the same time, Ireland and Scandinavian countries occupy the top of the leader board, followed by Luxemburg. The Kruskal-Wallis test results indicate four COVID-19 risk indicators that significantly differentiate the countries in the first year of the COVID-19 pandemic. Among the significant factors are not only COVID-19-related factors, i.e., the changes in residential human mobility, the stringency of anti-COVID-19 policy, but also strictly environmental factors, namely pollution and material footprint. It indicates that the most critical global environmental issues might be crucial in the phase of a future pandemic. Moreover, we detect eight readiness factors that significantly differentiate the analysed country groups. Among the significant factors are the economic indicators such as GDP per capita and labour markets, the governance indicators such as Rule of Law, Access to Information, Implementation and Adaptability measures, and social indicators such as Tertiary Attainment and Research, Innovation, and Infrastructure.
Methods for improving participation rates in national self-administered web/mail surveys: Evidence from the United States
Authors: West Brady T. , Zhang Shiyu , Wagner James , Gatward Rebecca , Saw Htay-Wah , Axinn William G.
Published: August 2023

In the United States, increasing access to the internet, the increasing costs of large-scale face-to-face data collections, and the general reluctance of the public to participate in intrusive in-person data collections all mean that new approaches to nationally representative surveys are urgently needed. The COVID-19 pandemic accelerated the need for faster, higher-quality alternatives to face-to-face data collection. These trends place a high priority on the evaluation of innovative web-based data collection methods that are convenient for the U.S. public and yield scientific information of high quality. The web mode is particularly appealing because it is relatively inexpensive, it is logistically flexible to implement, and it affords a high level of privacy and confidentiality when correctly implemented. With this study, we aimed to conduct a methodological evaluation of a sequential mixed-mode web/mail data collection protocol, including modular survey design concepts, which was implemented on a national probability sample in the U.S. in 2020–2021. We implemented randomized experiments to test theoretically-informed hypotheses that 1) the use of mail and increased incentives to follow up with households that did not respond to an invitation to complete a household screening questionnaire online would help to recruit different types of households; and 2) the use of modular survey design, which involves splitting a lengthy self-administered survey up into multiple parts that can be completed at a respondent’s convenience, would improve survey completion rates. We find support for the use of mail and increased incentives to follow up with households that have not responded to a web-based screening questionnaire. We did not find support for the use of modular design in this context. Simple descriptive analyses also suggest that attempted telephone reminders may be helpful for the main survey.
High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells
Authors: Schmitt Danielle L. , Dranchak Patricia , Parajuli Prakash , Blivis Dvir , Voss Ty , Kohnhorst Casey L. , Kyoung Minjoung , Inglese James , An Songon
Published: August 2023

We have previously demonstrated that human liver-type phosphofructokinase 1 (PFK1) recruits other rate-determining enzymes in glucose metabolism to organize multienzyme metabolic assemblies, termed glucosomes, in human cells. However, it has remained largely elusive how glucosomes are reversibly assembled and disassembled to functionally regulate glucose metabolism and thus contribute to human cell biology. We developed a high-content quantitative high-throughput screening (qHTS) assay to identify regulatory mechanisms that control PFK1-mediated glucosome assemblies from stably transfected HeLa Tet-On cells. Initial qHTS with a library of pharmacologically active compounds directed following efforts to kinase-inhibitor enriched collections. Consequently, three compounds that were known to inhibit cyclin-dependent kinase 2, ribosomal protein S6 kinase and Aurora kinase A, respectively, were identified and further validated under high-resolution fluorescence single-cell microscopy. Subsequent knockdown studies using small-hairpin RNAs further confirmed an active role of Aurora kinase A on the formation of PFK1 assemblies in HeLa cells. Importantly, all the identified protein kinases here have been investigated as key signaling nodes of one specific cascade that controls cell cycle progression in human cells. Collectively, our qHTS approaches unravel a cell cycle-associated signaling network that regulates the formation of PFK1-mediated glucosome assembly in human cells.
Safety outcomes of ticagrelor among patients with STE-ACS post streptokinase therapy-a retrospective observational study
Authors: Ueapornpanith Phornpaka , Buranakiti Boonyanuch , Chotayaporn Thanyalak , Phrommintikul Arintaya , Yoodee Voratima
Published: August 2023

From the restriction of access to primary percutaneous coronary intervention, about 46% of patients with ST-elevation acute coronary syndrome (STE-ACS) received fibrinolytic therapy as a reperfusion strategy; streptokinase is frequently used in Thailand. Despite the guidelines recommending potent P2Y12 inhibitors among these patients, the data are limited, especially among patients with STE-ACS post streptokinase therapy. The study was proposed to describe factors for P2Y12 inhibitors selection and evaluate outcomes of pharmacoinvasively treated STE-ACS receiving ticagrelor compared with clopidogrel in Thailand. We performed a retrospective observational study of patients with STE-ACS post streptokinase therapy followed by percutaneous coronary intervention (PCI) with coronary stent placement and receiving ticagrelor or clopidogrel as P2Y12 inhibitor treatment from January 2017 to June 2021. The primary outcomes described factors for P2Y12 inhibitor selection and evaluated safety outcomes with inverse probability weight (IPW) adjustment. The secondary outcome was a composite of all-cause death, myocardial infarction and stroke. The median time from streptokinase therapy to initiating ticagrelor in the switch group was 25.7 (IQR, 1.9–4.4) hours. The factors related to switching from clopidogrel to ticagrelor included young age, history of coronary artery disease (CAD), dose of streptokinase and use of intravascular imaging. Any bleeding events occurred among 83 patients (41.71%) in the switch group and 83 patients (41.09%) in the no switch group (adjusted HR 1.04, 95% CI 0.75–1.44; p = 0.826). The composite of efficacy outcomes occurred in 6 patients in the switch group (3.02%) and 12 patients (5.94%) in the no switch group (adjusted HR 0.57, 95% CI 0.21–1.57; p = 0.279). Conclusion: In real practice, ticagrelor switching among patients with STE-ACS post streptokinase therapy did not differ regarding safety outcomes and composite of efficacy outcomes compared with clopidogrel.
Is “earth” an animate thing? Cross-language and inter-age analyses of animacy word ratings in European Portuguese and British English young and older adults
Authors: Félix Sara B. , Poirier Marie , Pandeirada Josefa N. S.
Published: August 2023

Animacy plays an important role in cognition (e.g., memory and language). Across languages, a processing advantage for animate words (representing living beings), comparatively to inanimate words (i.e., non-living things), has been found mostly in young adults. Evidence in older adults, though, is still unclear, possibly due to the use of stimuli not properly characterised for this age group. Indeed, whereas several animacy word-rating studies already exist for young adults, these are non-existent for older adults. This work provides animacy ratings for 500 British English and 224 European Portuguese words, rated by young and older adults from the corresponding countries. The comparisons across languages and ages revealed a high interrater agreement. Nonetheless, the Portuguese samples provided higher mean ratings of animacy than the British samples. Also, the older adults assigned, on average, higher animacy ratings than the young adults. The Age X Language interaction was non-significant. These results suggest an inter-age and inter-language consistency in whether a word represents an animate or an inanimate thing, although with some differences, emphasising the need for age- and language-specific word rating data. The animacy ratings are available via OSF: https://osf.io/6xjyv/.
More Lonely Ere: Idiorrhythmic communities and the nostalgic lens
Authors: Hill Phil
Published: August 2023

This article discusses the photographic project, ‘More Lonely Ere’, made during the COVID-19 pandemic focusing on the community of Watford, Hertfordshire, where the author was based and unable to leave. Watford will be compared to Marion Shoard’s ‘edgelands’ and the concept of rurality will be used to situate Watford as a liminal space between city and countryside but also to demonstrate the limited locality and community during COVID-19. The article also considers Roland Barthes’ ‘Idiorrhythm’ describing how people share spaces but live according to individual daily rhythms. This connects ideas of community during a pandemic when people are expected to maintain separation from each other. The resulting photographs will be analysed in terms of a conscious ‘documentary aesthetic’ and photographic nostalgia, materiality and abstraction will be discussed. Comparisons are made to canonical works and also Robert Frost’s ‘Desert Places’ poem to provide useful metaphor and a framework for photographic work.
The curation of communities in Shipibo Onanyabo
Authors: Robinson Megan
Published: August 2023

In this article, I discuss how the logic of Shipibo ancestral healing or Onanyabo, is internal to Shipibo culture, and that such a logic is explicated in the creation and curation of Shipibo art across transnational boundaries. Moving from the term ‘network’ to ‘meshwork’, I explore how Shipibo Onanyabo operates across ontological difference, bringing together diverse mediums and perspectives. I consider how we might come to envisage the Shipibo community through the perspective of a meshwork, through recourse to the curation of Shipibo art in New York contemporary gallery spaces.
‘The Hidden Life of a Pavement Crack’
Authors: Wieland Susanne Elizabeth
Published: August 2023

These are a few of the infinite numbers of stories that were documented and analysed during a six-month observation of a single overlooked ecosystem and the connection it has to us and its surroundings. They are the stories of a single London pavement crack.
Entrevista com Mario Vedovello Filho
Authors: Vedovello Filho Mario , Villela Henrique , Bastos Marden , Santamaria Jr. Milton , Vedovello Silvia Amélia
Published: August 2023

Apresentar o professor Mario Vedovello Filho não é tarefa das mais fáceis, mas é, certamente, fascinante, por ser repleta de fatos, análises e histórias que contam sobre a evolução da Graduação, da Pós-graduação e, lógico, da Ortodontia. Tendo o privilégio de ser sua filha e parceira de trabalho, tenho o ângulo que certamente poucos conhecem daquele que sabe ensinar, dividir e delegar — características dos mestres. Nascido em Mogi-Guaçu, no interior de São Paulo, em 1945, logo conheceu a vocação política, sendo eleito vereador várias vezes. Faceta, essa, que mostra a capacidade de comunicação e a preocupação com a comunidade. Graduado cirurgião-dentista há mais de 50 anos, incorpora a luta pela classe odontológica e a formação acadêmica de qualidade. Em dezembro de 2022, o Prof. Mario Vedovello Filho completa 52 anos do seu título de Mestre em Ortodontia, obtido na Faculdade de Odontologia de Piracicaba (UNICAMP). Sua natureza destemida e a preocupação com a formação acadêmica fizeram-no trilhar um caminho ímpar. Há 34 anos é docente do Centro Universitário da Fundação Hermínio Ometto (FHO), em Araras/SP, tendo ocupado diversos cargos, como a coordenação do Curso de Graduação em Odontologia, a coordenação do Programa de Pós-graduação em Odontologia e a Pró-reitoria de Pós-graduação e Pesquisa. Por 12 anos ele foi membro do Conselho Estadual de Educação de São Paulo, órgão normativo, deliberativo e consultivo do sistema educacional público e privado do estado.
Protocolo para remoção de aparelhos fixos
Authors: Bastos Marden
Published: August 2023

INTRODUÇÃO: A remoção de aparelhos ortodônticos fixos exige cuidados, para minimizar os danos ao esmalte dentário. OBJETIVO: O presente trabalho tem como objetivo descrever um protocolo seguro para a remoção dos braquetes ao fim do tratamento ortodôntico. CONCLUSÃO: O uso de brocas multilaminadas de tungstênio em baixa rotação, que permitem visualizar e remover a resina remanescente após a retirada dos braquetes, e o posterior polimento do esmalte com discos Sof-Lex oferecem um protocolo seguro para finalização do tratamento.
Utilização do Bootstrap, Pin-lock e Double-Wedge na resolução do tracking no tratamento com alinhadores
Authors: Reis Rafaela Bahia Ribeiro , Rodrigues Guilherme Garcia , França Esdras de Campos
Published: August 2023

INTRODUÇÃO: Os movimentos extrusivos de incisivos laterais superiores estão entre aqueles que apresentam menor previsibilidade quando utilizamos alinhadores. O Bootstrap pode ser empregado como recurso auxiliar e promover a total extrusão desses dentes quando ocorre a perda de tracking. OBJETIVOS: Esse trabalho descreve o Bootstrap, recurso clínico auxiliar para recuperação do tracking de incisivos laterais superiores, e duas técnicas preconizadas pelos autores para manter a posição dentária com os alinhadores passivos até a confecção dos aparelhos de contenção definitivos: contenções Pin-lock e Double-Wedge. CONCLUSÃO: Por meio da técnica do Bootstrap seguida pela contenção imediata no último alinhador, seja do tipo Pin-lock ou Double-Wedge, a recaptura dos dentes que perdem tracking e sua contenção provisória são conseguidas de forma eficiente sem necessidade da confecção de alinhadores adicionais.
Abordagem da Classe II esquelética severa por retrognatismo mandibular: relato de caso
Authors: Shimizu Roberto Hideo , Shimizu Isabela Almeida
Published: August 2023

OBJETIVO: O presente relato de caso tem como objetivo apresentar o tratamento de um paciente com má oclusão de Classe II esquelética por retrognatismo mandibular acentuado, perfil convexo, linha mento-pescoço e terço inferior da face diminuídos. RELATO DO CASO: O paciente apresentava um bom padrão esquelético (mesofacial) e potencial de crescimento (início do surto pré-puberal); era portador de má oclusão de Classe II, divisão 1, com sobressaliência e sobremordida acentuadas, assim como uma curva de Spee acentuada. Primeiramente, ele foi submetido à disjunção palatina, com aparelho de Hyrax, e a expansão foi mantida com o uso de uma barra transpalatina estendida, confeccionada com fio de aço inoxidável de 0,8mm, até os primeiros pré-molares superiores. Aos 11 anos e 11 meses, com idade esquelética de 13 anos, instalou-se o aparelho de Herbst, que foi utilizado durante 12 meses. RESULTADOS: Obteve-se uma boa protrusão da mandíbula e iniciou-se o tratamento com Ortodontia Corretiva, que foi finalizada aos 14 anos e 4 meses. Na avaliação pós-contenção, aos 16 anos e 3 meses, observou-se uma boa estabilidade, inclusive com uma melhora do perfil facial, resultante de um crescimento mandibular favorável. CONCLUSÕES: A) O tratamento de pacientes Classe II esquelética severa com deficiência mandibular por meio da protrusão mandibular está indicado sempre que o paciente apresentar potencial de surto de crescimento e tendência de crescimento favorável (meso ou braquifacial); B) Obteve-se um resultado altamente satisfatório, tanto na correção das discrepâncias dentária e esquelética anteroposterior entre a maxila e a mandíbula, quanto na estabilidade do tratamento.
Mecânica ortodôntica e estética do sorriso: uma poderosa combinação em Ortodontia
Authors: Machado Andre Wilson , Brito Gabriela Meyge , Caldas Sergei Godeiro Fernandes Rabelo
Published: August 2023

OBJETIVO: Apresentar o caso clínico de um paciente com 27 anos de idade, que buscou tratamento para melhorar a estética do sorriso e corrigir dentes inferiores mal posicionados, antes da reabilitação protética. RELATO DO CASO: O paciente apresentava um sorriso assimétrico, com vários aspectos negativos. Na avaliação intrabucal, apresentava relação de caninos em Classe I no lado direito e Classe II no lado esquerdo, além de severa inclinação mesial e infraoclusão do primeiro molar inferior esquerdo, gerando a presença de dois planos oclusais. TRATAMENTO REALIZADO: O tratamento consistiu na utilização de mecânica segmentada com dois cantilevers para a verticalização dos primeiros molares inferiores e correção da discrepância do plano oclusal. Uma abordagem multidisciplinar foi utilizada na arcada superior para melhorar a estética do sorriso, por meio de alinhamento e nivelamento convencionais. RESULTADOS: A exposição gengival excessiva e as proporções dentárias alteradas foram corrigidas por meio de gengivectomia e restaurações dentárias. A correção da inclinação dos molares inferiores e a abertura de espaço para reabilitação foram realizadas com a técnica do arco segmentado, por meio de dois cantilevers. CONCLUSÃO: Esse relato de caso destaca a importância de combinar o conhecimento da mecânica ortodôntica com a estética do sorriso, para se obter resultados oclusais e estéticos ideais.
Entrevista com Ravindra Nanda
Authors: Nanda Ravindra , Guimarães Júnior Carlos Henrique , Uribe Flávio , Vaid Nikhlesh , Almeida Marcio
Published: August 2023

Com muita honra e apreço, apresento-lhes a entrevista com o amigo, o pesquisador, o mentor, o clínico e, se assim posso dizer, meu “pai” da biomecânica moderna: o Dr. Ravindra Nanda. Lembro-me, como se fosse hoje, a primeira vez que adentrei na Universidade de Connecticut, nos idos do ano de 2004... Senti até um friozinho na barriga, por estar no “berço da Ortodontia do Arco Segmentado”. Naquele instante, pensei: a vida é feita de escolhas, não é verdade? Então, eu escolhi trilhar exatamente a mecânica que, outrossim, fora desenvolvida por lá. A bem da verdade, em uma conversa com meu pai, Dr. Renato Almeida, comentei que naquela época eu estava um pouco insatisfeito com meus resultados na Ortodontia. Os casos estavam demandando o uso de muitos elásticos intermaxilares para finalizar, tomando, sobretudo, muito tempo de tratamento. Ele me indagou: "Porque você não vai buscar conhecimento da técnica segmentada de Connecticut?". Afinal, o Dr. Nanda tem uma célebre frase que diz: “Em um tratamento ortodôntico que leva, em média, dois anos de duração, durante um ano você trata os problemas da má oclusão do seu paciente e, no outro ano, você acaba tratando os efeitos colaterais advindos da sua técnica”. Sem dúvida, a aplicação de conceitos do arco segmentado permite minimizar os efeitos colaterais durante a movimentação dentária.
Adaptação de dente provisório no aparelho fixo
Authors: Bastos Marden
Published: August 2023

Objetivo: Este trabalho descreve um protocolo para a colagem de um braquete com slot 0,018” em um provisório de acrílico, com auxílio de cera utilidade e resina flow com carga, para conferir estética ao tratamento ortodôntico em pacientes com ausência de dentes anteriores.
Colagem indireta digital: relato de caso
Authors: Bernal Junior Basilio , Jorge Ana Carolina Tedesco
Published: August 2023

OBJETIVO: O presente estudo tem como objetivo apresentar de forma prática e objetiva, por meio de um caso clínico, a otimização da colagem indireta, utilizando guia de colagem indireta criada por meio do fluxo de trabalho digital. MÉTODOS: Após análise criteriosa do caso, optou-se pela técnica de colagem indireta dos braquetes. O escaneamento foi exportado para o software OrthoAnalyzer 2017 (3Shape, Copenhagem, DK), que permite o posicionamento correto dos braquetes e tubos nas faces vestibulares dos dentes e a criação de uma guia indireta, a qual foi gerada em impressora da marca Anycubic, modelo Mono X. A resina utilizada para impressão foi a OrthoFlex, da marca Yller. RESULTADOS: Os resultados obtidos por meio da colagem indireta virtual se mostraram bastante eficientes, em especial em relação ao tempo de cadeira e à qualidade do alinhamento e nivelamento, quando comparada aos métodos convencionais. CONCLUSÃO: O fluxo de trabalho digital associado à técnica da colagem indireta trouxe uma maior precisão no posicionamento dos braquetes, favorecendo um tratamento mais curto e com melhor finalização, e podendo-se imprimir a guia na própria clínica, com uma impressora 3D.
Editorial v10n2
Authors: Editorial Conselho
Published: August 2023

Editorial do número 2 do volume 10 da Aniki: Revista Portuguesa da Imagem em Movimento.
Cinema no mundo árabe: histórias e abordagens além da análise fílmica
Authors: De Lima Morgana Gama
Published: August 2023

Recensão crítica do livro Cinema in the Arab World: New Histories New Approaches, de Ifdal Elsaket, Daniel Biltereyst e Philippe Meers (2023).
Der große Baukasten
Authors: Boetticher Alexandra Druzynski von
Published: August 2023

In Eberswalde (Brandenburg), a model house estate built in 1931 by Hirsch Kupfer- und Messingwerke has been preserved. The special feature of the eight house types built in lightweight construction is their outer skin of copper sheets. The structure consists of wall segments prefabricated in the factory, which were plugged together on the building site using patented connecting elements. One of the houses was built under the supervision of Walter Gropius, who for a short period of time was in charge of the factory’s house construction department. Here he tried to realize his idea of the building kit on a large scale, in which houses were to be produced on stock in factories. A considerable amount of plans as well as correspondence prove how profoundly Gropius was concerned with the development of the copper houses.
M.A.N.-Stahlhäuser
Authors: Irmler Bernhard , Nagel Elke
Published: August 2023

The construction experience of M.A.N. company was reflected in the M.A.N. steel house in the sophisticated panel construction and the simplicity of the joints. The designers met the requirement of creating a modern functional home with the exceptionally high-quality façade modules, efficient insulation, double-glazing of the windows and integration of the most modern building services for maximum living comfort. With the standardisation of construction elements, M.A.N. chimed with the spirit of the times, and the extremely short construction time of just a few weeks was also advantageous. While the contemporary clients appreciated performance and equipment, the traditional shape imitating cubature and façade design failed. Responding to the clients’ wishes by developing variations distinguished the M.A.N. steel house as the most flexible prefabricated house. At the same time, it was precisely the individualisation that brought the manufacturing company disproportionately high production costs and prevented profitable series production.
Das Quelle-Fertighaus
Authors: Fissabre Anke , Rottke Evelin
Published: August 2023

The steel prefabricated family house ›Quelle-Fertighaus‹ designed and constructed by the German company Quelle, is an innovative modular system commercialised in 1962. All aspects of the Quelle-Fertighaus are planned on the principle of minimal effort for maximal flexibility. The clever design of the ground plan based on a 4 m × 7 m module offers the flexibility for either one to three additional modules.

The steel construction is innovative and unique, consisting of load-bearing portal frames acting as braces. The house design is furthermore characterised by a simple metrical grid layout and the practical placement of the foundation and basement, which allowed the very cost-effective production and the lowest price for a prefabricated family house in Germany during the postwar era. Nowadays its portal-frame-construction offers an interesting approach for its renovation and transformation according to present building demands.
Alltag im Hoesch-Bungalow
Authors: Parussel Isolde
Published: August 2023

In the 1950s the Dortmund-based steel manufacturer Hoesch developed a process of coating strip steel with synthetic material naming the product Platal. One idea of selling Platal was using it for serially prefabricated bungalows. In the spring of 1964, the first prefabricated steel bungalows could be delivered. But instead of selling 1.000 houses per year as planned, the estimation is that until the end of production in 1966 only 150 to 200 unities had been produced in various sizes. Seven of those steel bungalows were erected by Hoesch in Hombruch, a southern suburb of Dortmund, and were rented out to senior executives of Hoesch.
NaCl regulates goldfish growth and survival at three food supply levels under hypoxia
Authors: Yang Xueyi , Zhao Jing , Zhang Yumeng , Zhang Jiarui , Pan Zhiyong , Xu Xiaowen , Weng Yingye , Su Xinyu , Shi Mingyan
Published: August 2023

NaCl has beneficial effects in preventing fish disease. However, the effects of NaCl in regulating fish growth and survival at different food supply levels under hypoxic conditions are unknown. Herein, the effects of NaCl on body weight, survival rate (SR), H2O2 content, lipid peroxidation, protein carbonylation, antioxidant (superoxide dismutase [SOD], catalase [CAT], and glutathione peroxidase [GPX]) enzyme activities, and the glutathione (GSH) content were investigated in goldfish (Carassius auratus) livers at three food supply levels (50, 200, and 400 mg day−1 fish−1) under hypoxic conditions. The highest and lowest SRs were detected in the 200 and 400 mg food groups, respectively. Interestingly, 50 mM NaCl markedly elevated survival, but not the body weight of goldfish. Enhanced H2O2 content; SOD, CAT, and GPX activities; GSH content; and reduced lipid peroxidation and protein carbonylation were detected in goldfish livers after NaCl treatment compared with those in the control. However, these effects of NaCl were dramatically attenuated by 50 µM hydroxychloroquine, an inhibitor of autophagy. This showed that nutrition stress reduced goldfish survival, which could be improved by NaCl via regulation of the antioxidant system and autophagy under hypoxic conditions.
Tight focusing field of cylindrical vector beams based on cascaded low-refractive index metamaterials
Authors: Ke Lan , Li Chenxia , Zhang Simeng , Fang Bo , Tang Ying , Hong Zhi , Jing Xufeng
Published: August 2023

Using low-refractive-index metamaterials, we design a transmission-type radial-angular cylindrical vector beam generator. A high numerical aperture lens is constructed using an asymmetric meta-grating structure. The metamaterial vector beam generator and the meta-grating lens are physically cascaded to obtain the tight focusing characteristics of the vector light field. The vector beam generator module and the meta-lens module are prepared by 3D printing technology, and the near-field test has been carried out on the samples in the terahertz band. Using the physical cascading method, two modules are cascaded to construct a vector beam tight focusing device, and the focusing electric field distribution test has been carried out. The use of 3D printing technology for sample preparation further reduces the manufacturing difficulty and production cost, and ensures the realization of its design function on the basis of miniaturization and light weight, which provides the possibility for the research of tight focusing field regulation in the terahertz band.
Changes to the Term of Office of Constitutional Justices in Law Number 7 of 2020 concerning the Constitutional Court: Discourse on Legal Reform in the Independence of Judicial Power in Indonesia
Authors: Ratri Safitri Yosita , Huda Muhammad Wahyu Saiful
Published: August 2023

Indonesia is a rule-of-law country certainly in every activity regulated by law. including government positions. In 2020, the Indonesian government has issued Law Number 7 of 2020 concerning the Constitutional Court. However, this law has various problems both formally and materially. One of the highlights is the extension of the term of office of the Constitutional Court which was originally 5 years to a maximum of 15 years. This drastic change certainly makes the Indonesian people astonished. And many have submitted requests for review of the law to the Constitutional Court, because extending the term of office could violate the constitutional rights of the people who wish to also serve as Constitutional Justices, causing a loss of sense of legal justice. Therefore, the writer wants to analyze this problem by using the normative juridical method. And will compare it with several countries in order to get the right analysis. In this study, it was found that the extension of the term of office was too long and had the potential to be an act of abuse of power.
Sounding the Justice for Child: Does Restorative Justice Matters?
Authors: Fridayani Helen Diana , Putri Dina Desvita Pramesti
Published: August 2023

Restorative justice is gaining relevance in Indonesia as an alternative approach to resolving legal cases, focusing on restoring relationships among perpetrators, victims, and society. It aims to address the needs, rights, and welfare of children, allowing child offenders to take responsibility for their actions and repair the harm caused. The successful implementation of restorative justice in Indonesia includes facilitating dialogue between victims and perpetrators, aiding victims' emotional recovery, and engaging children in behavior improvement activities. However, challenges persist in raising awareness and garnering support from the community and justice system, necessitating proper training for an equitable and effective process. While restorative justice serves as a valuable means of providing justice for children, it may not be suitable for all cases, occasionally undermining justice for child victims. This paper analyzes how restorative justice can offer justice to children in Indonesia and delves into legal reform, particularly in juvenile delinquency, concerning the application of this approach. Nonetheless, it acknowledges that in specific instances, restorative justice might prove inappropriate, potentially compromising a sense of justice, especially for child victims.
JOB SATISFACTION AS A MODERATING VARIABLE BETWEEN THE EFFECT OF COMPENSATION AND LEADERSHIP STYLE ON TURNOVER
Authors: Fadhlan Abdi
Published: August 2023

The company's goals depend not only on modern equipment, good facilities, and infrastructure but also on the people who carry out this work. A company's success is strongly influenced by human resources, which are the company's driving force. Quality human resources can be seen from how the output is displayed. Therefore, companies must pay attention to the actions and needs of their workers to provide work results that are in line with company expectations. This study aims to see how the effect of compensation and leadership style on turnover is moderated by job satisfaction. This research uses quantitative methods. The sample size for this study was 107 employees of PT. Locco Mandiri Indonesia by collecting data through a questionnaire. SPSS or PASW (Predictive Analytics Software) is used to analyze the data in this report. The findings of this study are: 1) Compensation has a positive and significant effect on turnover intention. 2) Leadership style has a positive and significant effect on turnover intention. 3) Job satisfaction has a positive and significant effect on turnover intention. 4) Compensation has a positive and significant effect on turnover intention, moderated by job satisfaction. 5) Leadership style has a positive and significant effect on turnover intention moderated by job satisfaction.
THE EFFECT OF HALAL TOURISM DEVELOPMENT ON THE INCOME OF MSMEs AROUND PADANG BEACH
Authors: LARASATI MAYANG
Published: August 2023

MSMEs are an important part of the economy. Many efforts have been made by the government to support the performance of MSMEs, one of which is through the tourism object development sector. The existence of a tourist object is expected to be able to encourage MSMEs income in the tourist attraction area. This study uses a quantitative method with the aim of seeing the effect of developing halal tourism objects with location, promotion, accessibility, facilities, and accommodation variables on MSME income around Padang Beach. The research sample is 100 MSMEs around Padang Beach. SPSS version 25 was used to analyze the data in this study. The results of the study show that: 1) location has a positive and significant effect on MSMEs income; 2) tourism promotion has a positive and significant effect on MSMEs income; 3) accessibility has a positive and significant effect on MSMEs income; 4) facilities have a positive but not significant effect on MSMEs income; 5) accommodation has a negative and insignificant effect on MSMEs income; 6) location, tourism promotion, accessibility, facilities, and accommodation all simultaneously have a positive and significant effect on the income of MSMEs around Padang Beach.