bluuebunny/crossref_metadata_2025 huggingface dataset:
Patient’s Right to Protection of Personal Data in the Legal System of Bosnia and Herzegovina
Authors: Bevanda Marko , Čolaković Maja
Published: January 2021

Health-related personal data belong to a category of sensitive data which, therefore, must be specially protected. The protection of personal health data is one of the patients’ fundamental rights. Doctors protect their patients’ interests only when the information gained about patients, while providing them medical treatment, are kept secret. In this paper, the authors provide an overview of the legal framework for the protection of health-related personal data in the legal system of Bosnia and Herzegovina. In addition to the analysis of the relevant legal provisions and considering the situation in practice, it can be concluded that formal harmonisation of legislation with the acquis communautaire in this field is not followed by effective implementation of regulation in practice.
Integrated Management of Insect Vectors of Plant Pathogens
Authors: Chandi Ravinder Singh
Published: January 2021

A vector is an organism capable of transmitting pathogens from one host to another. Among the plant pathogen transmitting agencies, insect vectors are most important and various plant pathogens in crops are transmitted by insects. Insect vectors are much more hazardous because small population of vector can spread the pathogen in whole of the field or to new areas. These are difficult to manage and hence multi-pronged strategy should be adopted. To effectively manage insect vectors of plant pathogens there is a need to look into the careful timing of application of chemicals, integrated treatment with vector sampling, estimation of threshold level of vectors, assessing infection of pathogen at varying period of the year and combining insecticides with other means of control such as resistant cultivars, natural enemies, inclusion of plant products, cultural practices, biotechnology tools etc. An integration of control measures will be more effective and ecologically sound than any single method to control insect vectors of plant pathogens. The control of insect vectors with the use of various tactics should be used to reduce the severity and to delay appearance of disease.
chGRP78 is Required for the Activation and Phosphorylation of AKT1 at Serine 478 in Chicken Sells
Authors: Choi H. , Kim Y.D. , Jung S.K. , Sureshkumar S. , Oh K.B. , Yang H. , Byun S.J.
Published: January 2021

Background: Chicken serum-mediated proliferation regulates chGRP78 to prevent apoptosis in chicken cells via chGRP78-mediated anti-apoptosis. However, the precise molecular mechanisms underlying the chGRP78-mediated protection against apoptosis remain undefined. In an earlier study, we have shown that chGRP78 is critical for chicken embryo fibroblast (CEF) and DF-1 cell proliferation. Methods: In this experiment, we highlight AKT1 as a key target of GRP78 during apoptosis. We used 2D gel-based proteomics and bioinformatics prediction analysis for our studies. Result: Here, we detected chGRP78 binding sites in AKT1-rgulated proteins. chGRP78 promoted AKT1 activation and chGRP78 silencing decreased AKT1 levels. Taken together, we suggest that the AKT1-mediated signaling pathway plays a critical role in GRP78-stimulated fibroblast survival and anti-apoptosis. Our findings have important implications for the maintenance of chicken fibroblast cells via the inhibition of apoptosis.
The Morphometric Scale to Predict the Live Weight of Malpura Sheep in Semi-arid Region of Rajasthan
Authors: Kumar Arun , Mallick P.K. , Misra S.S. , Sharma R.C. , Gowane G.R.
Published: January 2021

Background: The Malpura sheep is hardy breed of semi-arid region of Rajasthan. Farmers do not get the due share for their heavy weight lambs as animals are never sold on weight basis. Researchers have worked out the ways of predicting the live weight of sheep/goats using body measurements. However, very few studies have tried to address this issue, especially in India. Aim of this study was to construct a prediction scale for live weight of sheep using simple measure of heart girth and body length, such scale will further benefit the shepherds to guess the live weight of the lambs sold and expect the desired price from the customer. Methods: The present study was conducted on 1164 records of 823 Malpura sheep at CSWRI, Avikanagar. The data on live weight (N=1164) and corresponding morphometric measures on heart girth and body length were digitalized and subjected to analysis. we used 14 linear predictors and regressed them on the live weight to obtain the estimates of regression, coefficient of determination and derived the prediction equations using the regression coefficients for prediction of live weights. Result: Our study revealed that it is possible to create a measurement scale for prediction of live weight of the sheep using simple arithmetic. Several linear regression scales using body length and heart girth were developed. The best scale (L+G) had a prediction equation as: Y = -49.743+0.576L+0.562G, where Y is live weight. The R2 was 0.883, which was not significantly more than linear regression scale (L+G). This will help the farmers to quite confidently score animals for their live weights across all the age groups. With the help of measurement tape, he can easily measure the heart girth and the body length of the sheep.
Exploring Feeding Potential of Stovers from Novel Sorghum (Sorghum bicolor L.) Cultivars by In vitro Fermentation Pattern, Gas Production, Microbial Abundance and Ruminal Enzyme Production in Buffalo
Authors: Dey Avijit , Paul S.S. , Umakanth A.V. , Bhat B.V. , Lailer P.C. , Dahiya S.S.
Published: January 2021

Background: Crop residues play a central role in ruminant’s diet in developing countries. Due to low in nutritional quality, there is limitation in ruminant production through feeding of these residues. Therefore, production of quality crop residues through plant breeding programme without conceding grain yield is of prime importance. The present experiment envisaged the feeding value of stovers from three different novel sorghum (Sorghum bicolor L.) cultivars by in vitro fermentation pattern, gas production, microbial abundance and ruminal enzyme production in buffalo. Methods: Stovers from three different genotypes of sorghum cultivars viz. normal sorghum (CSV-27), brown midrib (bmr) sorghum (SPV-2018) and sweet sorghum (CSH 22SS) were analyzed for proximate principles and fibre fractions. Each stover sample was incubated (200 ± 5 mg) with 30 ml buffered rumen fluid in 100 ml calibrated glass syringes at 39ºC for 24 h following in vitro gas production system using rumen liquor from Murrah buffaloes. The gas production in each syringe was recorded during incubation at 4, 8, 12, 18 and 24 h intervals. Incubations were terminated at 24 h and methane concentration in the head space gas from syringes incubated with each stover sample was analyzed. Supernatant of each syringe contents was analyzed for volatile fatty acids (VFA) estimation. Truly degradable dry matter (TDDM) was determined and microbial biomass production (MBP) and portioning factor (PF) was calculated. Ruminal fibrolytic enzyme production and microbial abundance in each syringe content was estimated. Result: The stover of bmr sorghum showed highest organic matter, followed by normal sorghum and lowest in sweet sorghum. The neural detergent fibre (NDF) ranges between 69.22 to 74.65%, with highest in bmr sorghum and lowest in sweet sorghum. The stover sample of bmr sorghum contained lowest (P less than 0.05) acid detergent fibre (ADF) among the three cultivars examined, which resulted with highest (P less than 0.05) hemicellulose (37.72%) content. Lowest acid detergent lignin (ADL) was found in stovers of bmr cultivar (1.27%) and highest in sweet sorghum (8.36%). The fermentation pattern of bmr sorghum stovers exhibited higher (P less than 0.05) total gas production, dry matter degradability, VFA production, ruminal enzymes (CMCase, xylanase, acetyl esterase) and abundance of total ruminal bacterial population than normal and sweet sorghum stovers. Therefore, this study establishes the enhanced feeding value of stovers from bmr sorghum cultivar compared to normal and sweet sorghum cultivars for ruminant production.
Macroscopic, Histomorphological and Histochemical Studies on the Kidneys of Guinea Fowl (Numida meleagris)
Authors: Singh Gajendra , Meshram Balwant , Joshi Hemant
Published: January 2021

Background: Kidneys, the paired organ which essentially plays for excreting nitrogenous wastes, excessive water, inorganic salts and toxic substances produced during the process of body metabolism. Maintenance of osmotic regulation and homeostatic fluid balance of the body has also be performed by kidneys. Each of the kidneys filtrate carried to cloaca by respective ureter from where the urine leaves the body. The present macroscopic, histomorphological and histochemical studies undertaken on the Kidneys of Guinea fowl (Numida meleagris) is nothing but the attempt to widen our thrust area for that bird which is nonexistent as on documentation. Methods: The present studies were carried upon 12 pairs of in-vitro kidney samples in Guinea fowl. Gross morphology and morphometrical observations were carried on fresh specimens. Histological studies were carried on fixed samples those were processed for dehydration, clearing, embedding into paraffin and sections of 5-6 μ thickness were obtained. Different staining procedure as to Haematoxylin and Eosin, Silver orcein, Aniline blue and Weigert’s staining methods were employed for different histological components. The histochemical and histoenzymic studies were also accomplished with Periodic acid Schiff‘s (PAS), Alcian blue methods (pH-2.5) and Gomori’s cobalt method for Alkaline phosphatase and Acid phosphatase. The Succinic dehydrogenase enzyme was also estimated on cryostat sections. Result: The observations on kidneys of Guinea fowl were accomplished after macroscopic, histomorphological and histochemical means. This reddish-brown colored paired organ of kidneys was retroperitoneally placed in synsacral fossa and had incomplete division of three parts. The wrapping material of capsule was the dense connective tissue. The outer cortex and inner medulla had different parts of nephrons. Two types of nephrons viz. mammalian type (with Henle loop) and reptilian type (without Henle loop) were observed. Collagen, elastic and reticular fibers were there in different components of the kidney. Histochemically it has determined the secretion of neutral as well as acidic mucopolysaccharide substances. PAS activity was observed at mesangial cells and basement membrane of DCT. The Alkaline phosphatase showed the positive activity in capsule, brush border of proximal and distal convoluted tubules. The Acid phosphatases were showing intense activity in parietal and visceral layer of renal corpuscles, lumen and basement membrane of PCT. The intense activity of Succinic dehydrogenase showed at PCT, DCT, collecting tubule whereas renal corpuscles showed feeble activity.
Heterosis, Potence Ratio and Correlation of Vegetative, Yield and Quality Traits in Tomato Genotypes and their Performance under Arid Region
Authors: Alsadon A. , Solieman T.H.I. , Wahb-Allah M.A. , Helaly Amira A. , Ali A.A.M. , Ibrahim A.A. , Saad M.A.O.
Published: January 2021

Background: The possibility of selecting the best genotypes to develop good hybrid varieties of tomatoes, as well as heterosis, potence ratio and correlation of vegetative characteristics, yield and quality in tomato genotypes and their performance under arid region. Methods: Four commercial tomato cultivars (Money Maker, Pakmore VF, Strain-B and Tanshet Star) and two breeding lines (L05960 and TL01899) and their 15 F1 hybrids, using a half-diallel cross, under arid conditions were used to estimate heterosis, potence ratio and correlation coefficients among all possible pairs of important tomato traits. Result: various degrees of dominance effects for some traits were detected in the general performances of the F1 hybrids, while, other traits illustrated the presence of partial- to under-recessiveness. Heterosis percentages reflected positive desirable effects in ten F1 hybrids for some traits. Most F1 hybrids outperformed their respective parents for fruit set, fruit length, fruit diameter, total soluble solids, fruit dry weight, number of fruits per plant and total fruit yield per plant. Some of the genotypes (i.e., parents and/ or hybrids) offer opportunities as a genetic source of heat tolerant breeding genetic material adapted to high temperature under the arid conditions reported in this study. Significant positive and desirable correlations were found between 41 possible pairs of traits, whereas significant negative and undesirable correlations were found between 13 possible pairs of the traits.
Production Potential of Short Duration Red Gram [Cajanus cajan (L.) Millsp.] in the Southern Laterites of Kerala
Authors: Devaraj G. Anjana , Isaac Sheeba Rebecca
Published: January 2021

Red gram [Cajanus cajan (L.) Millsp.] is a new introduction in the southern laterites of Kerala. The field experiment was laid out in factorial RBD to assess the performance of the short duration varieties of red gram, APK 1 and Vamban (Rg) 3 under two spacings (40 cm x 20 cm and 60 cm x 30 cm) and three nutrient levels (40:80:40, 30:60:30 and 20:40:20 kg NPK ha-1) in the Instructional Farm, College of Agriculture, Vellayani, Kerala during November 2018 to March 2019. Significant variations were recorded in growth and yield attributes and among the varieties, APK 1 was found to be superior with a seed yield of 997.78 kg ha-1. The closer spacing of 40 cm x 20 cm and the highest dose of 40:80:40 kg NPK ha-1 recorded the significantly highest seed yields of 1195.00 kg ha-1 and 1055.83 kg ha-1, respectively. The three factor interaction also revealed APK 1 and Vamban (Rg) 3 to record superior seed yields at the closer spacing and higher nutrient dose. The short stature, lower branching tendency, early flowering nature and higher yields in APK 1, proved its suitability for cultivation in southern laterites of Kerala and the agronomic package would involve sowing seeds at a spacing of 40 cm x 20 cm with an NPK dose of 40:80:40 kg ha-1.
Bioefficacy of Chlorantraniliprole 18.5 SC Against Pod Borer, Helicoverpa armigera (Hubner) and Pod Fly, Melanagromyza obtusa (Malloch) in Pigeonpea, Cajanus cajan (Linn.) Millsp.
Authors: Khinchi S.K. , Kumawat K.C.
Published: January 2021

Background: Pod borer, Helicoverpa armigera (Hubner) and pod fly, Melanagromyza obtusa (Malloch) are important pod boring insects infesting the pigeonpea, Cajanus cajan (Linn.) Millsp. throughout the world. A number of synthetic insecticides are known to be effective against these borers but most of them have been phased out as a result of high toxicity to the pollinators and other biotic agencies, therefore, a new molecule, chlorantraniliprole has been tested for bioefficacy against these insect pests. Methods: The experiment was conducted during Kharif, 2017 in a Randomized Block Design (RBD) with 7 treatments and 3 replications. Observations were made to record pod borer, H. armigera and pod fly, M. obtusa maggot present before treatment imposition and 3, 7 and 14 days after each spray from five randomly selected and tagged plants/ plot. From the data recorded per cent reduction in population over control was calculated. The per cent pod damage was calculated by counting damaged pods out of healthy pods. The numbers of coccinellids and spiders were recorded on 5 randomly selected plants before treatment and 7 and 14 days after spray (DAS) in each treatment. Result: The chlorantraniliprole 18.5 SC was found most effective @ 200 ml/ha which was found at par with chlorantraniliprole 18.5 SC @ 150 ml/ha and chlorantraniliprole 18.5 SC (Market sample) @ 150 ml/ha for suppression pod borer, H. armigera and pod fly, M. obtusa. The yield was maximum and at par in the chlorantraniliprole 18.5 SC @ 200 ml/ha (18.25 q ha-1), chlorantraniliprole 18.5 SC @ 150 ml/ha (17.82 q ha-1) and chlorantraniliprole 18.5 SC (Market sample) @ 150 ml/ha (17.42 q ha-1). Predatory population of coccinellids and spiders after imposing the treatments declined to some extent at seven days after treatment, however, increased after 14 days. Based on the results, the use of chlorantraniliprole 18.5 SC @ 150 ml/ha was most effective to control pod borer and pod fly in pigeonpea crop.
Romatoid artrit tedavi prensipleri: Neye geçiş yapalım?
Authors: KARABULUT Gonca , ÖZBALKAN AŞLAR Zeynep
Published: January 2021

Romatoid artrit erişkinde en sık görülen inflamatuar artrittir. Remisyon veya düşük hastalık aktivitesi
sağlanana kadar tedavi modifikasyonları yapılmalıdır. Gelecekte yapılacak daha kapsamlı çalışmalar
ile bireyselleştirilmiş tedavilerin geliştirilmesi mümkün olabilecektir.
Skleritler ve üveitler
Authors: GÜVEN YILMAZ Suzan
Published: January 2021

Sklerit ve üveitler akut kırmızı göze neden olan, görme kaybı potansiyeli taşıyan gözün nadir görülen

inflamatuar hastalıklarındandır. Kırmızı göz tanısında görmeyi tehdit edici hastalıkların benign

durumlardan ayırımı önemlidir. Bu makalede sklerit ve üveitin belirtileri, klinik özellikleri ve ayırıcı tanısı

tartışılmıştır.
Global Value Chains (GVCS) and COVID-19 Pandemic
Authors: Varnavskii V.
Published: January 2021

The article discusses the status of Global Value Chains (GVCs) amid the COVID 19 pandemic and their influence on world economic development. Key aspects of the world economy and GVCs transformation in the context of the COVID 19 are studied. A brief overview of the economic literature and development of theoretical frameworks and concepts of Global Value Chains as well as globalisation and “slowbalisation” is provided. The article focuses on estimates of key indicators published by international bodies, such as the United Nations, UNCTAD, UNIDO, OECD, WTO, IMF and others. Various think tanks and other institutions such as World Economic Forum, European Central Bank, McKinsey Global Institute, Deloitte, NBER have been analyzing GVCs’ contribution to the transmission of the COVID 19 macroeconomic shocks across countries. A quantitative assessment of participation in GVCs for countries and regions based on available data in the Trade in Value Added (TiVA) database are discussed. Specific attention is paid to the key GVCs indicators, including exports of intermediate goods and foreign value added share of gross exports. Special attention is paid to the economic downturn in the United States and characteristics of GVCs involving enterprises located in Wuhan (China), which is very important to many global supply chains. Various kinds of long-term trends and structural changes are analyzed. It is noted that gross domestic product (GDP) of the USA in constant 2012 prices (ignoring inflation) fell in the second quarter of 2020 compared to the previous quarter by 31.7% but only 9.1% compared to the first quarter of 2020. It is concluded that improving supply chains’ recovery ability will be an important factor for restoring global economic activity in post-coronavirus times.
Saudi Arabia and Israel: the Palestinian Context
Authors: Kosach G.
Published: January 2021

The article examines the issues related to the change in the Saudi Arabia’s policy towards Israel in the context of Riyadh’s approaches to solving the Palestinian problem. The author emphasizes that the positive dynamics taking place in the evolution of Saudi-Israeli interaction in recent years is determined by the intra-Saudi socio-economic and political transformation, including changes in public opinion regarding Israel, as well as significant shifts in the development of the Middle East regional situation, inter alia those proclaimed by the United Arab Emirates (as well as Bahrain) heading towards a settlement with Israel. At the same time, the emergence of a tendency to support the course towards normalizing relations with Israel in the context of the current Saudi internal political situation also marked a public demarcation in relation to initiatives to support the Crown Prince. If his supporters act, among other things, as supporters of normalization, then opponents see contacts with the Jewish state as “a betrayal of Arab national interests”. Noting that the current Saudi-Israeli rapprochement is largely determined by a joint interest in confronting Iran, the author, nevertheless, sees the most important reason for the continuing Saudi unwillingness to normalize relations with the Jewish state in the unresolved Palestinian problem on the basis of the “two states” principle. At the same time, the author believes that this principle itself is an instrument of Saudi foreign policy, thanks to which Riyadh seeks to exclude the possibility of Israeli hegemony in the future post-confrontational Middle East. This means, in particular, that the achievement of mutual understanding will become a reality only if the Israeli regional policy is adjusted so as not to pose a threat to Saudi interests.
Extension of Equivalent System Mass for Human Exploration Missions on Mars
Authors: Berliner Aaron , Makrygiorgos George , Hill Avery
Published: January 2021

NASA mission systems proposals are often compared using an equivalent system mass (ESM) framework wherein all elements of technology to deliver an effect- its components, operations and logistics of delivery- are converted to effective masses since this has a known cost scale in space operations. To date, ESM methods and the tools for system comparison have not considered complexities wherein systems that serve a mission span multiple transit and operations stages, such as would be required to support a crewed mission to Mars, and thus do not account for the different mass equivalency factors operational during each period and the inter-dependencies of the costs across the mission. Further, ESM does not account well for the differential reliabilities of the underlying technologies. Less reliability should incur an equivalent mass cost for technologies that might otherwise provide a mass advantage. We introduce an extensions to ESM to address these limitations and show that it provides a direct method for analyzing, optimizing and comparing different mission systems. We demonstrate our extended ESM (xESM) calculation with crop production technologies -- an aspect of the developing offworld biomanufacturing suite -- since it represents a case with strong coupling among stages of the mission and a relatively high-risk profile.
The Localization Subgingival Margins of Cavity: A New Classification
Authors: Bulbuk Oleksandr , Bulbuk Olena , ROZHKO Mykola
Published: January 2021

Background. Restoring large defects with proximal caries extending below the cemento-enamel junction and cavity margins located beneath the gingival tissues represents a very common clinical situation. The aim of this article is to propose a clinical classification of the localization subgingival margins of cavity.Material and methods. Diagnosis is carried out by periodontal probe perpendicular to the long axis of the tooth in the deepest point of the cavity’s margin. To describe the localization subgingival margins of cavity we use exponent which value is equal to the distance (integer number expressed in millimeters) of the level of epithelial attachment to the margin of the cavity. Three periodontal examiners, with >10 years of periodontal practice, were required to attend a calibration session aimed at the validation of the proposed classification. Results. The intrarater and interrater agreement among the localization subgingival margins of cavity: for intrarater agreement ranged from 0.74 to 0.95 (almost perfect agreement), whereas interrater agreement ranged from 0.26 to 0.59 (moderate agreement).Conclusions. The classification the localization subgingival margins of cavity is useful for reaching a more precise diagnosis.
Magnetic Field Energy Harvesting with a Lead-Free Piezoelectric High Energy Conversion Material
Authors: Sung Tae Hyun , WANG QUAN , Kim Kyung Bum , Woo Sang Bum
Published: January 2021

A high-performance Lead-free Piezoelectric Energy Harvester (LPEH) based on a Ba0.85Ca0.15Ti0.90Zr0.10O3 + CuO 0.3 wt% (BCTZC0.3) composite was fabricated by sintering at 1450℃. The BCTZC0.3 composite, which has an enhanced high-energy-conversion constant (〖d_33×g〗_33), shows improved piezoelectric power-generation performance when compared with conventional piezoelectric energy harvesters. The BCTZC0.3-based LPEH produces instantaneous maximum power of 8.2 mW and an energy density of 107.9 mW/cm3 in a weak magnetic field of 250 μT. This energy harvester can be used to charge a capacitor and operate a wireless sensor network (WSN) system to provide temperature sensing and radio-frequency (RF) transmission in a 250 μT magnetic field. The proposed LPEH is a promising green-energy device for potentially self-powering WSN systems when applied.
Scientist as Parrhesiastes
Authors: Scotognella Francesco
Published: January 2021

The scientific community of the XX and XXI centuries is a very large companionship, very fragmented and spread all over the world. Moreover, the status of the scientist, which in most cases is a member of the States’ apparati, is significantly different with respect to the one of the scientists up to the First World War.The concepts of scientific revolution of Thomas Kuhn and scientific anarchy of Paul Feyerabend should be reconsidered in this contest. In particular, the anarchist modus operandi should be shifted from the scientific method, that has become significantly standardized with protocols, to the sociology of the scientific community. A pluralism of the scientific method is possible, but an anarchy in the relationships among scientists emerges as more important. The scientist is in many cases a parrhesiastes, a person that says the truth even when he is going to pay because of that, that defends the developed theory or model, by respecting the protocols established in the scientific community. On the other side, each scientist should be a patient beholder that accepts the more solid, and intersubjectively recognized, theories of other scientists.
Helmet Detection Based on Deep Learning and Random Forest on UAV for Power Construction Safety
Authors: Yan Guobing ,   Guangdong Power Grid Corporation 757 Dongfeng East Road, Guangzhou, Guangdong 510600, China, Sun Qiang , Huang Jianying , Chen Yonghong
Published: January 2021

Image recognition is one of the key technologies for worker’s helmet detection using an unmanned aerial vehicle (UAV). By analyzing the image feature extraction method for workers’ helmet detection based on convolutional neural network (CNN), a double-channel convolutional neural network (DCNN) model is proposed to improve the traditional image processing methods. On the basis of AlexNet model, the image features of the worker can be extracted using two independent CNNs, and the essential image features can be better reflected considering the abstraction degree of the features. Combining a traditional machine learning method and random forest (RF), an intelligent recognition algorithm based on DCNN and RF is proposed for workers’ helmet detection. The experimental results show that deep learning (DL) is closely related to the traditional machine learning methods. Moreover, adding a DL module to the traditional machine learning framework can improve the recognition accuracy.
ANALISIS DAYA DUKUNG TIANG AKSIAL TUNGGAL DENGAN METODE STATIS DAN DINAMIS TERHADAP HASIL UJI PILE DRIVING ANALYZE (PDA) PADA PEKERJAAN PONDASI PROYEK JAKARTA BOX TOWER
Authors: Sari Evi Puspita , Prihantono Prihantono , Musalamah Sittati
Published: January 2021

The purpose of this research is to know the ratio of bearing pile capacity with some static and dynamic calculation method to Pile Driving Analyze (PDA) dynamic test result. The analysis uses static calculations using several methods namely, Meyerhoff, Vesic, α Thomlinson, and α Terzaghi, Peck and Mesri methods.Consultant calculation using Reese & Wright method. Dynamic bearing capacity uses jacking pile record  from Hydrolic System Pile Driving (HSPD)  and Pile Driving Analyze test results. The results showed that Reese & Wright method with SPT is the most closely approximated PDA test result with percentage 74,72%; 76.79% and 82.83% for number of pile 310, 368 and 763. While the result of comparison of jacking pile record that most approached PDA is on pile number 638 with a percentage of 82.83%. The largest settlement results are at pile number 310 and 763 with a decrease of 26.3 mm and 25.9 mm with α Vesic+Terzaghi, Peck and Mesri method
PEMANFAATAN ABU DASAR (BOTTOM ASH) DAN KAPUR SEBAGAI PENGGANTI SEBAGIAN SEMEN PADA PAVING BLOCK SESUAI DENGAN SNI 03-0691-1996
Authors: Hayni Ria Nur , Prihantono Prihantono , Anisah Anisah
Published: January 2021

The purpose of this research is to utilize bottom ash and lime as substitute partial cement to know quality of product based on SNI 03-0691-1996 about paving block both physically and mechanically so that can reduce amount of B3 waste unused. This research used an experimental method, the population of paving block using bottom ash and lime as substitute partial of cement within 5 percentage 25%, 30%, 35%, 40%, and 45% of the amount of cement used in the normal mix. This research examined the six test, namely: testing of compressive test, wear resistance, resistance to sodium sulfate, water absorption and testing measure. The result showed that the difference of quality of product which have different percentage.Percentage 25% and 30% showed B quality based on SNI 03-0691-1996. Percentage 35% showed C quality and 40% showed a D quality based on SNI 03-0691-1996. Percentage 45% showed result below quality based on SNI 03-0691-1996. The optimum paving block produced in this research is 30% which has average 20,66 MPa result on compressive test and maximum 21,86 MPa, 0,086 mm/minute maximum for wear resistance from 35% percentage and 2,25% is maximum amount for water absorption test from 30% percentage. In this research all product which used bottom ash and lime has average 0.744% resistance of sodium sulfate.
Effect of Obstructive Sleep Apnea on Immunity in Cases of Chronic Rhinosinusitis With Nasal Polyps
Authors: Kim Dong-Kyu , Lee Byeong Chan , Park Ki Joon , Son Gil Myeong
Published: January 2021

Objectives. Chronic rhinosinusitis with nasal polyps (CRSwNP) is a more severe inflammatory form of CRS that often coexists with obstructive sleep apnea (OSA). However, little is known about the relationship between OSA and the immune profile in patients with CRSwNP. We aimed to investigate the immune profile of patients with CRSwNP according to OSA severity.Methods. This study included 63 patients with CRSwNP and nine control subjects. Protein levels of inflammatory mediators were determined using multiplex immunoassays. All patients underwent standard polysomnography.Results. In patients with eosinophilic CRSwNP (ECRSwNP), interleukin (IL)-6 and chemokine [C-X-C motif] ligand (CXCL)-1 (type 1 immune-related markers) were upregulated in cases of moderate-to-severe OSA. Additionally, IL-4, IL-13, C-C motif chemokine (CCL)-11, CCL-24 (type 2 immune-related markers), and IL-17A (a type 3 immune-related marker) were present at elevated levels in patients with moderate-to-severe OSA. Although there were no significant differences in type 1, 2, or 3 immune-related markers among patients with non-eosinophilic CRSwNP (NECRSwNP) according to the severity of OSA, transforming growth factor-beta expression was higher in those with moderate-to-severe OSA. Furthermore, in ECRSwNP with moderate-to-severe OSA, associations were detected between serum markers and some upregulated inflammatory markers.Conclusion. OSA may increase the heterogeneity of the immune profile (types 1, 2, and 3) in patients with ECRSwNP, but not in those with NECRSwNP.
Chondral Lesions of the Knee: An Evidence-Based Approach
Authors: Dekker Travis J. , Aman Zachary S. , DePhillipo Nicholas N. , Dickens Jonathan F. , Anz Adam W. , LaPrade Robert F.
Published: January 2021

➤ Management of chondral lesions of the knee is challenging and requires assessment of several factors including the size and location of the lesion, limb alignment and rotation, and the physical and mental health of the individual patient.

➤ There are a multitude of options to address chondral pathologies of the knee that allow individualized treatment for the specific needs and demands of the patient.

➤ Osteochondral autograft transfer remains a durable and predictable graft option in smaller lesions (<2 cm2) in the young and active patient population.

➤ Both mid-term and long-term results for large chondral lesions (≥3 cm2) of the knee have demonstrated favorable results with the use of osteochondral allograft or matrix-associated chondrocyte implantation.

➤ Treatment options for small lesions (<2 cm2) include osteochondral autograft transfer and marrow stimulation and/or microfracture with biologic adjunct, while larger lesions (≥2 cm2) are typically treated with osteochondral allograft transplantation, particulated juvenile articular cartilage, or matrix-associated chondrocyte implantation.

➤ Emerging technologies, such as allograft scaffolds and cryopreserved allograft, are being explored for different graft sources to address complex knee chondral pathology; however, further study is needed.
Next-Generation Marrow Stimulation Technology for Cartilage Repair
Authors: Shah Sarav S. , Lee Sonia , Mithoefer Kai
Published: January 2021

» Given the relatively high prevalence of full-thickness articular cartilage lesions, including in patients who are <40 years of age, and an inability to detect some of these lesions until the time of arthroscopy, there is value in performing a single-stage cartilage procedure such as marrow stimulation (MS).

» While the positive outcomes of first-generation MS (namely microfracture) have been observed to drop off after 24 months in several studies, improvements have been seen when compared with preoperative conditions for lesions that are 2 to 3 cm2 in size, and MS is considered to be a procedure with technical simplicity, fairly short surgical times, and relatively low morbidity. A recent study showed that autologous chondrocyte implantation (ACI) and osteochondral allograft (OCA) transplantation remain viable treatment options for chondral defects of the knee in the setting of failed MS.

» Basic science principles that have been elucidated in recent years include (1) the creation of vertical walls during defect preparation, (2) an increased depth of subchondral penetration, (3) a smaller awl diameter, and (4) an increased number of subchondral perforations, which are all thought to help resolve issues of access to the mesenchymal stromal cells (MSCs) and the subchondral bone structure/overgrowth issues.

» Pioneering and evolving basic science and clinical studies have led to next-generation clinical applications, such as a hyaluronic acid-based scaffold (ongoing randomized controlled trial [RCT]), an atelocollagen-based gel (as described in a recently published RCT), a micronized allogeneic cartilage scaffold (as described in a recently completed prospective cohort study), and a biosynthetic hydrogel that is composed of polyethylene glycol (PEG) diacrylate and denatured fibrinogen (as described in an ongoing prospective study).

» This review summarizes important points for defect preparation and the recent advances in MS techniques and identifies specific scaffolding augmentation strategies (e.g., mesenchymal augmentation and scaffold stimulation [MASS]) that have the capacity to advance cartilage regeneration in light of recent laboratory and clinical studies.
Memoria celebrativa y memoria narrativa: los templos de la fama en los libros de caballerías.
Authors: Admin Ojs
Published: January 2021

Las representaciones de edificios, galerías, entornos pintados o enriquecidos con estatuas permiten reflexionar sobre un aspecto desatendido de los libros de caballerías españoles: los “templos de la memoria”. Se ponen en relación ejemplos tomados de Amadís de Gaula y Sergas de Esplandián (1496-1510); Clarián de Landanís (1518); Lisuarte de Grecia, Florisel de Niquea, Amadís de Grecia (1514-1535); Silves de la Selva (1546); Olivante de Laura (1564); Espejo de príncipes (1587) y las continuaciones italianas de Mambrino Roseo: Palmerino (1560) y Sferamundi (1558-1565) con la tratadística y artes plásticas de la época: el Teatro de la Memoria de Giulio Camillo Delminio (1480-1544); el cenotafio del emperador Maximiliano en la Iglesia de Innsbruck (1553); el proyecto de Anton Francesco Doni para Arquà Petrarca (h. 1560); el Teatro Olimpico de Andrea Palladio en Vicenza (1579); el Museo de Paolo Giovio cerca del lago de Como (1543) y el salón de los Fasti del palacio Farnese de Caprarola (1559-1575).
Encuentros con Marc Vitse, un maestro en el arte de revelar
Authors: Admin Ojs
Published: January 2021

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La literatura en el abismo. Salas Barbadillo y las colecciones de metaficciones | Manuel Piqueras Flores
Authors: Admin Ojs
Published: January 2021

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Miguel Hernández y Leopoldo de Luis: dos poetas comprometidos | Aitor L. Larrabide (ed.)
Authors: Admin Ojs
Published: January 2021

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Carmen Conde desde su Edén | Francisco Javier Díez de Revenga
Authors: Admin Ojs
Published: January 2021

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A history of the development of the mathematics and statistics support community in the United Kingdom. Part 1: From alpha to sigma
Authors: Lawson Duncan
Published: January 2021

In terms of the history of mathematics higher education, mathematics and statistics support (MSS) is a very recent development, existing as a formal feature for less than 50 years.Â  However, in this short time, MSS has displayed its own characteristics.Â  A particularly notable feature of MSS in the United Kingdom (and in other countries) has been the way in which practitioners have collaborated with each other, almost from the outset.Â  This collaboration has led to the creation of a community (the sigma network) with a written constitution and formal membership.Â  This two-part article traces the history of the development of the MSS community in the UK from its earliest incarnations to the present day.Â  The first part of the article reviews the period from the early 1990s to 2005 during which time the key events were the rise and demise of the Mathematics Support Association and the creation of sigma, Centre of Excellence in University-wide Mathematics and Statistics Support.Â
A trial of resources to support students with Dyslexia
Authors: Heraty Calum , Mac an Bhaird CiarÃ¡n , Mulligan Peter , O'Malley James , O'Neill Rachel
Published: January 2021

In this paper we report on a pilot of resources to support students with dyslexia conducted at a university in Ireland. We give brief background to the development of these resources and describe the steps taken to pilot them in a mathematics support centre. We outline the feedback received from tutors and students, and close with observations on how the pilot outcomes may influence the future implementation of these and other similar resources.
Reflections on Remote Teaching
Authors: Jones Daniel , Meyer John , Huang Jingyu
Published: January 2021

The COVID-19 pandemic has forced us to reconsider the way we teach our students. The inability of UK-based lecturers to deliver via traditional lecture-based courses in China (due to ongoing travel restrictions) has been an obstacle to overcome but also an opportunity to investigate innovative remote-teaching methods. Here we review a case study based on teaching three different year groups at the Jinan University - University of Birmingham Joint Institute during the early part of 2020. We reflect on how technology was used, draw conclusions and discuss potential opportunities for the future of remote-teaching.
Extensive antimicrobial resistance and plasmid-carrying resistance genes in mcr-1-positive E. coli sampled in swine, in Guangxi, South China
Authors: Yuan Jingzhi , Wang Xiaoye , Shi Dali , Ge Qiang , Song Xingxing , Hu Wen , Wei Deyuan , Ge Chenling , Li Xun , Hu Chuanhuo
Published: January 2021

Background: The discovery of the superbug mcr-1-positive Escherichia coli (MCRPEC) has drew greet attention. Swine-origin multi-drug resistant MCRPEC has been a potential threat to public health and safety. However, there were few detailed studies have been reported on swine MCRPEC in Guangxi, South China.Results: In this study, thirty-three MCRPEC strains were detected from 142 E. coli strains from 116 samples in Guangxi in 2018. Which could be classified into eight unique STs and a total of six incompatibility plasmid groups (IncFI, IncHI1, IncY, IncN, IncI1 and IncX1). After that, the susceptibility of MCRPEC isolates to 27 antimicrobial agents belonging to 17 antimicrobial categories was tested. There were nineteen E. coli resistant to 3rd and 4th generation cephalosporins and twelve E. coli resistant to carbapenem resistan. Importantly, the MCRPEC showed high resistance highly resistance for imipenem and meropenem, which were forbidden to use in livestock production. Three MCRPEC strains were further proved to be extensively drug-resistant (XDR), and the other isolates were multi-drug-resistant (MDR). Furthermore, we found that the plasmid-carrying resistance genes coexisted with the mcr-1 gene of the MCRPEC isolates. Which were listed as follows: β-lactamase antimicrobial resistance genes e.g. ESBL genes (blaCTX-M14, blaCTX-M24, blaCTX-M123, blaOXA-1), plasmid-mediated AmpC (pAmpC) gene (blaCMY-2), the carbapenem resistance gene (blaNDM-5), and non-β-lactamase antimicrobial resistance genes (qnrA, qnrB, qnrS, aac(6’)-Ib-cr, tetA, tetB, sul1, sul2, floR, aadA).Conclusion: Thirty-three mcr-1-positive E. coli isolates in Guangxi displayed a wide profile of antimicrobial resistance. Plasmid-carrying resistance genes might be the main cause of MCRPEC multidrug resistance. This study highlighted the necessity for long-term surveillance of mcr-1-positive E. coli in pigs.
Risk and Protective Factors Associated Mental Health among Female Military Veterans: Results from the Veterans’ Health Study
Authors: Adams Richard , Hu Yirui , Figley Charles R. , Urosevich Thomas G. , Hoffman Stuart N. , Kirchner H. Lester , Dugan Ryan J. , Boscarino Joseph J. , Withey Carrie A. , Boscarino Joseph A.
Published: January 2021

Background: This study focuses on factors that may disproportionately affect female veterans’ mental health, compared to men, and is part of a larger study assessing the prevalence of mental health disorders and treatment seeking among formerly deployed US military service members.Methods: We surveyed a random sample of 1,730 veterans who were patients in a large non-VA hospital system in the US. Based on previous research, women were hypothesized to be at higher risk for psychological problems. We adjusted our results for confounding factors, including history of trauma, childhood abuse, combat exposure, deployments, stressful life events, alcohol misuse, psychological resources, and social support. Results: Among the veterans studied, 5% were female (n=85), 96% were White (n=1,161), 22.9% were Iraq/Afghanistan veterans (n=398), and the mean age was 59 years old (SD=12). Compared to males, female veterans were younger, unmarried, college graduates, had less combat exposure, but were more likely to have lifetime PTSD (29% vs. 12%.), depression (46% vs. 21%), suicidal ideation (27% vs. 11%), and lifetime mental health service use (67% vs. 47%). Females were also more likely to have low psychological resilience and to have used psychotropic medicines in the past year. Using multivariate logistic regression analyses that controlled for risk and protective factors, female veterans had greater risk for lifetime PTSD, depression, suicidal thoughts, and for lifetime use of psychological services, compared to males. Since 95% of the population in this study were male and these results may have been statistically biased, we reran our analyses using propensity score matching. Results were consistent across these analyses.Conclusion: Using a sample of post-deployment veterans receiving healthcare services from a large non-VA health system, we find that female veterans are at greater risk for lifetime psychological problems, compared to male veterans. We discuss these findings and their implications for service providers.
The Effect of the Mobile ‘Blood Pressure Management Application’ on Hypertension Self-Management Enhancement: A Randomized Controlled Trial
Authors: Bozorgi Ali , Hosseini Hamed , Eftekhar Hassan , Majdzadeh Reza , Yoonessi Ali , Ramezankhani Ali , Mansouri Mehdi , Ashoorkhani Mahnaz
Published: January 2021

Background: Self-management of hypertension is of great significance given its increasing incidence and its associated disabilities. In view of the increased use of mobile health in medicine, the present study evaluated the effect of a self-management application on patient adherence to hypertension treatment.Methods: This clinical trial was performed on 120 hypertensive patients who were provided with a mobile intervention for 8 weeks and followed-up until the 24th week. Data on the primary outcome (adherence to treatment) and secondary outcomes (adherence to the DASH diet, regular monitoring of blood pressure, and physical activity) were collected using a questionnaire and a mobile application, respectively. The inter-group change difference over time was analyzed using repeated measures ANOVA (General Linear Model).Results: The treatment adherence score increased by an average of 5.9 (95% CI: 5.0-6.7) in the intervention group compared to the control group. Scores of 'adherence to the low-fat and low-salt diet plans' were 1.7 (95% CI: 1.3-2.1) and 1.5 (95% CI: 1.2-1.9), respectively. Moreover, moderate physical activity increased to 100.0 minutes (95% CI: 61.7-138.3) per week in the intervention group.Conclusion: The treatment and control of blood pressure require a multifaceted approach given its complexity and multifactorial nature. Considering the widespread use of smartphones, mHealth interventions can be effective in self-management and better patient adherence to treatments. Our results showed that this application can be used as a successful tool for hypertension self-management in patients attending public hospitals in developing countries.Trial registration: This study was registered in the Iran Randomized Clinical Trial Center under the number IRCT2015111712211N2 on January 1st 2016.