bluuebunny/crossref_metadata_2025 huggingface dataset:
Validation of the Turkish Version of the Skin Cancer Quality of Life Impact Tool (SCQOLIT): A Health Related Quality Of Life Questionnaire for Non-Metastatic Melanoma and Non-Melanoma Skin Cancer
Authors: Karakok Hilayda , Bostancı Seher , Akay Bengü Nisa , Caliskan Deniz , Ateş Can , Kose Serdal Kenan
Published: February 2023

Introduction: Skin cancer is the third most common type of cancer worldwide that has increased in incidence. Quality of life (QoL) instruments have been developed to measure the efficacy of treatments of  cancers.

Objectives: The only validated tool that can be used in both nonmetastatic skin cancer types is the SCQOLIT. This study aimed to validate the Turkish version of the Skin Cancer Quality of Life Impact Tool (SCQOLIT).  

Methods: A total of 141 patients diagnosed and treated for skin cancer within the previous 3 months were included.  The tool was translated into Turkish in accordance with International Translation Guidelines. The Dermatology Quality of Life Index that was used for external validation. Patient demographics were recorded.

Results: Question 3 had a factor load of 0.372, indicating the inadequacy of this question in predicting QoL, a point that the original study did not mention. The SCQOLIT had external validity, convergent validity and internal consistency (Cronbach alpha=0.863), and test-repeat-test correlation coefficient was 0.824 (95% confidence interval; 0.644 – 0.918). Patients diagnosed with melanoma had poorer QoL scores. High-risk tumor characteristics in nonmelanoma skin cancer and stage of melanoma had no impact on QoL (p=0.235 for basal cell carcinoma, p=1.00 for squamous cell carcinoma, p=0.635 for melanoma). 

Conclusions: The Turkish version of the SCQOLIT is validated. Age was shown to have a statistically significant negative correlation with QoL, while Fitzpatrick skin type, gender, risk classification, stage, history of skin cancer, family history of skin cancer and treatment modality had no effect on QoL.
JAPAN IN THE WORKS OF ORTHODOX MISSIONARIES: ACCORDING TO THE MEMOIRS OF FR. ANDRONIK NIKOLSKY (1897-1899)
Authors: Павлова Оксана Сергеевна
Published: February 2023

В статье рассмотрен недолгий опыт служения о. Андроника Никольского в Японии по материалам его воспоминаний. Интерес представляют наблюдения автора о культуре, ментальности японцев, а также о характере и направлениях миссионерской деятельности среди местного населения.

The article discusses the short-lived experience of Fr. Andronik Nikolsky in Japan based on the materials of his memoirs. Of interest are the author's observations about the culture, mentality of the Japanese, as well as about the nature and directions of missionary activity among the local population.
Nueva definición del Donatismo: Nuevos caminos de investigación
Authors: Tilley Maureen A. ,   Order of Augustinian Recollects
Published: February 2023

El artículo propone cuatro líneas de investigación para los futuros estudios sobre el donatismo, particularmente en las ramas de la eclesiología y teología sacramental. En primer lugar, considera que el donatismo ha de ser analizado no solo como un complemento de los escritos de Agustín, sino como un movimiento con entidad propia. En segundo lugar, el donatismo fue un movimiento que implicó otras muchas cosas más de lo que el mismo Agustín condenó en sus escritos como errores del propio movimiento cismático. En tercera instancia, el donatismo no fue un movimiento estático: tuvo un pasado antes de Agustín, y un Nachleben después de la muerte de Agustín. Finalmente, el donatismo no fue un movimiento monolítico, por lo que es preciso estudiar no “el donatismo”, sino “los donatismos” que existieron
El patrimonio eclesiástico de la Iglesia donatista
Authors: Buenacasa Carles ,   Order of Augustinian Recollects
Published: February 2023

El artículo hace la presentación de los bienes eclesiásticos de la Iglesia donatista en el siglo IV y V, tomando como referencia las fuentes contemporáneas, particularmente a Optato de Milevi y los escritos de san Agustín, sin excluir fuentes donatistas como las Passiones de diversos mártires donatistas. Se aborda en primer lugar la cuestión de las basílicas, posteriormente se dedica un apartado para destacar la lucha entre los católicos y los donatistas por la posesión de dichas basílicas y los efectos de los documentos oficiales sobre la titularidad de dichas basílicas. Se presenta también la cuestión de los bienes inmuebles, así como los ingresos adicionales de la Iglesia donatista que podían provenir de bienhechores privados, herencias, la explotación del culto de los mártires, la apropiación de los templos paganos y la renta de las tierras imperiales.
La identidad cristiana en el debate entre católicos y donatistas
Authors: Zocca Elena ,   Order of Augustinian Recollects
Published: February 2023

El artículo hace la presentación del intenso debate en el cual se enfrentaron los católicos y los donatistas en torno a la identidad. Se hace la presentación de los documentos de ambas partes en donde las dos reivindicaban para sí el título de Catholica, y esto porque con aquel término, más allá de las especificaciones técnicas indicadas por cada uno, pretendían cualificarse a sí mismos como los únicos auténticos cristianos o, lo que es lo mismo, como la única auténtica Iglesia. El artículo señala la base escriturística de la polémica, y cómo los católicos supieron adecuar la propia autorepresentación al cambio de las circunstancias, mientras que los donatistas permanecieron rígidamente anclados en una definición propia que no podía responder a las peticiones de sociedad en continua agitación. El artículo señala cómo esto determinó la supervivencia de los católicos y la lenta desaparición de los donatistas
Deciphering Humanity: What Polanyi and the Rosetta Stone Can Teach Us About Being Human
Authors: Steiger Andy ,   The Polanyi Society
Published: February 2023

Polanyi is widely known for his development of personal knowledge, but he was also keenly inter­ested in what can be called, personal existence. The historical backdrop of reviving, the once dead language of, Egyptian Hieroglyphics provides valuable insights into Polanyi’s critique of objectiv­ism and deciphering a human ontology. From applying physiognostic to telegnostic information to understanding static and dynamic meaning, Polanyi’s philosophy of language and machines provides a wealth of vantage points from which to study who and what we are.
Technical and Vocational Education and Training for Producing Graduates with Necessary Skills on Demand of Labour Market: The Moderating Role of Labour Market Information
Authors: Kaula Stephen
Published: February 2023

This study analyzed the effects of technical and vocational education and training in acquiring graduates with the necessary skills that are labor market on demand. This analysis came following many graduates completing TVET college studies but finding they are not conforming to the skills a labor market is in demand with. To address this gap, the study used quantitative research approaches. While the research design was explanatory, the sampling technique was simple random sampling from a population of 3000 unit of analysis: students, graduates, tutors, and management staff from 3 selected NACTVET colleges, and 254 samples of respondents was obtained. Moreover, data collection from the sample extracted used a questionnaire. Before actual data analysis, a pilot survey, data cleaning, and factor analysis were conducted. The actual data analysis employed multiple linear regression from which the results were:-TVET-theoretical, practical, and behavioral attitudinal education found to be positively and significantly related to the production of resourceful graduates if the labor market information is intruded in the model system. These analytical results suggest that education stakeholders, policymakers, and curriculum developers adopt the model this study introduced by calling for the moderation role of labor market information.
The Views of Greek Educators on Evaluation Techniques: The Case of Model Experimental Schools
Authors: Αnastasia Papadopoulou
Published: February 2023

The term "evaluation of the educational work" and, respectively, of the teachers was established in our country during the post-colonial period. The following questions particularly concerned both the educational community and the state in general: "How are or should the results of the evaluation be used?", "Can all aspects of the work produced at the school unit level and the effects of teachers on their students be objectively measured and evaluated?", "How can the subjective element be reduced in the procedure of teacher evaluation?", "Is it possible to apply uniform evaluation criteria to schools that operate in heterogeneous socio-economic, cultural, or geographical environments?", "What is the role of the teachers and the Management of each school and school counselor as well as other actors of the school community (students, parents, other staff)?"
The answer to the above questions comes through the research carried out on 405 teachers in Greece and highlights various philosophical, political, and pedagogical dimensions concerning the purpose of Evaluation, the bodies, forms, techniques, and evaluation criteria.
Menumbuhkan Kepekaan Lingkungan Siswa melalui Pembelajaran Sejarah Terkait Dampak Eksploitasi Alam Masa Revolusi Industri
Authors: Setianingsih Sarah
Published: February 2023

Humans will always depend on the environment. The environment is where living things live. Thus the need to protect the environment for the survival of living things around it. Concern for and sensitivity to the environment must be cultivated from an early age in order to maintain the survival of humans, animals and plants, as well as to preserve nature for the future. Growing environmental sensitivity can be integrated through learning in schools, one of which is learning history. By studying history, it will give students an understanding of the importance of the past as a form of awareness in the present and the future. One of the themes that can be raised in learning history is the industrial revolution, how this revolution caused changes in human life, but in fact had a bad impact on the environment, such as the exploitation of nature.
Manajemen Pendidikan Islam Budaya: Historisitas, Konsepsi dan Aktualisasi Manajemen Pendidikan Agama Islam Transformatif
Authors: Yohanik Yohanik
Published: February 2023

This paper uses a mixer methodology, first with literature review and second with field studies, the theme raised is Islamic Education Cultural Management: History, Conception, and Management of Transformative Islamic Education Actualization, in this paper there are three fundamental questions; first, what is the concept of Cultural Management of Islamic Education in Islam.  Second, what is the history, conception of Islamic religious education management, Islam, transformative culture in Indonesia and third, what is the contribution of Islamic education management in a transformative Islamic culture in the Islamic education space in Islam in Indonesia.  Which is where teacher supervision is a definite process.  Furthermore, culture becomes part of the culture of the local community which cannot be separated from the language of the community. Culture (often called local wisdom) will be passed down through generations through oral stories. Islamic religious education based on truth and nobility, distancing oneself from unreal thoughts, even far from the origins of unpleasant behavior or influence.  Islamic religious leadership education is important for moral (character)/ethics is easy), then the soul (emotional realm) is not only a cognitive and psychomotor realm, but 4) synergizes with culture, Islamic religious education, and tourism, and needs to be developed in a coordinated mannerin Islamic religious education with real regional characteristics
Computer aided detection and classification of plant leaf diseases using Deep Convolutional Neural Network
Authors: Srimani Pendyala Shamili , S.Jayachitra
Published: February 2023

Agriculture is the backbone of the Indian economy and the production rate of agricultures is based on detection and classification of plant leaf diseases. The conventional machine learning methods are failed to meet the maximum classification accuracy. Therefore, this article is focused on implementation of transfer learning models for feature extraction. Initially, non-local means filters (NLMF) are used to perform the preprocessing operation, which removed the different types of noises and also enhances the region of plant diseased region. Then, hybrid k-means clustering (HKMC) is used to localize the diseased region by segmentation operation. In addition, log of gradients descriptor (LOG) is used to extract the diverse features from the dataset. Finally, deep convolutional neural network (DCNN)is used to classify the different types of plant diseases. Further, the simulation results show that the proposed method resulted in superior performance as compared to existing approaches for both subjective and objective analysis.
Deep learning framework for classification of COVID-19 from Chest X-rays
Authors: Gopatoti Anandbabu
Published: February 2023

The Coronavirus Disease 2019 (COVID-19) has emerged as the most pressing health concern in recent years. In addition, a wide variety of severe acute respiratory syndrome-related COVID-19 strains are now in the process of developing (SARS). Therefore, the identification of all of these variations utilising a Real-time polymerase chain reaction (RT-PCR) test is a challenging endeavour that takes a significant amount of time. Due of the intricate structure of the chest x-ray (CXR) picture, traditional approaches were unable to correctly categorise the COVID-19 at an early stage. As a result, the primary emphasis of this paper is placed on the use of an artificial intelligence strategy that is based on deep learning convolutional neural networks (DLCNN) for the classification of COVID-19 illness. In the beginning, the hybrid features are extracted from the CXR dataset by using stacked auto ensemble (SAE), a technique that retrieved features by partitioning data into various subsets. This approach was used. After that, a DLCNN model is trained with these characteristics in order to classify COVID-19 for each test CXR picture. According to the findings of the simulations, the suggested classification led to superior results in terms of both subjectivity and objectivity in comparison to both traditional machine learning and deep learning approaches.
Deep learning framework for cancer type classification using genome sequencing with AlexaNet
Authors: kumar Reddy C.Sateesh , Billa Poornaiah
Published: February 2023

Tumors and cancers are the major diseases in humans and early prediction of cancers can save human lives. Cancer genome sequencing involves sequencing the whole genome of a group of cancer cells. It is a chemical laboratory approach for describing and identifying cancerous RNA or DNA cells.Therefore, this work develops adeep learning algorithm for classifying the cancer diseases from genomic sequences. Initially, Ada-boost descriptor is used to extract the deep features from the dataset, which identifies the inter and intra relationship between multiple correlated cancers. Then, deep learning based AlexNet model is used to classify the different types of cancers. Further, the simulation results shows that the proposed method resulted in superior performance as compared to state of art approaches
Factors influencing Individual Behavior Intention of using E-government applications in Sindh Province
Authors: Dr. Saima Tabassum  , Siddiqui Imdad Hussain , Muhammad Saad Hassan Shahid  , Dr. Adnan Khurshid  , Muhammad Zaman Siddiqui
Published: February 2023

Electronic Application are used everywhere in order to carry out marketing and organizational activities. Although the literature that may link the application with governmental activities are rare. Moreover, the users of electronic Application are mostly consumers. Therefore, through using the same target audience this study is specifically focused towards the understanding of e-application and its influencing factors linked with governmental operations. This study highlights the essential elements that affect the adoption of e-government apps in the departments and field offices of the Sindh government. It also enables functionaries of the Sindh government for adopting e-government apps at several levels of government. Quantitative techniques have been selected for the purpose of analysis which indicated that social influence & trust in e- govt application have significant effect use of e-govt application. Similarly, moderation of some of the demographic factors like age and gender are also potent in defining the relationship.
Calidad de vida en pacientes con insuficiencia cardiaca en atención primaria (CAL-ICAP)
Authors: García Aurora María Fernández
Published: February 2023

Antecedentes: La insuficiencia cardiaca (IC) es una enfermedad crónica que compromete la calidad de vida (CV). La mayoría de los estudios se desarrollan en el ámbito hospitalario y en consultas externas. Los realizados en Atención Primaria son escasos.

Objetivo: Evaluar la CV de los pacientes en estabilidad clínica y en su entorno habitual.

Método: Estudio descriptivo transversal de 143 pacientes en 33 centros de salud rurales y urbanos. Cuestionarios de calidad de vida: Minnesota Living with Heart Failure (MLHFQ) y Euroqol (EQ) 5D-5L. Variables independientes: perfil sociodemográfico y clínico, grado de dependencia y nivel de autocuidado.

Resultados: La edad media fue de 76,3 ± 9,6; 50,34% hombres, 17,4% con grado III-IV de la NYHA (New York Heart Association) y 72% con fracción de eyección preservada. Puntuación media total del MLHFQ: 32,44 ± 21,49; dimensión física: 17,78 ± 11,72; dimensión emocional: 8,43 ± 6,71. Media de la EVA del EQ-5D-5L: 57,8 puntos. El grado de dependencia se asoció significativamente con la CV (p = 0,0001). La hipertensión arterial y la edad se asociaron con algunas dimensiones de la CV. Todos ajustados por sexo, edad y NYHA. No encontramos asociación con el grado funcional NYHA ni el sexo.

Conclusiones: Los pacientes con IC clínicamente estables y en su entorno habitual tienen una mala CV. Aunque el género y la clasificación NYHA no fueron significativos, las mujeres y el grado funcional III-IV obtuvieron peores puntuaciones.  El nivel de dependencia y la edad se asocian con la CV. Las características clínicas mostraron resultados inconsistentes.
Generator fleet characteristics model
Authors: O Fallon Cheyney , Gopstein Avi
Published: February 2023

This manuscript presents the Generator Fleet Characteristics Model (GFCM), a general purpose tool for the analysis of power system operations, economics, and resilience. The GFCM is a collection of MATLAB functions that use publicly available data with national coverage to produce year-long (8760 hour) analyses of the electric grid at the balancing authority level. As the name implies, the GFCM builds up a series of snapshots of electric grid conditions and outcomes using the economics of the generator feet as a starting point for understanding system complexity and dynamics. While the synchronous inertia application we present here uses the GFCM to build a detailed picture of the present state of electric grid operations and market outcomes, the model is designed to facilitate counterfactual study through the comparison of model outputs by an analyst that systematically varies inputs. The GFCM forms a modeling framework intended to aide in the formulation of what if questions regarding how the grid might operate under changing ambient conditions while harnessing evolving technologies.
Naviguer entre normes masculines et féminines en entrepreneuriat : les défis des entrepreneures burkinabè1
Authors: Redien-Collot Renaud , Alexandre Laurice , Akouwerabou Lirassê
Published: February 2023

Cette étude examine la capacité des entrepreneures burkinabè à pérenniser leur activité dans le secteur formel du commerce et des services, sachant qu’elles doivent faire face à différentes formes de subordination et d’exclusion, dont l’articulation complexe n’a pas encore été clarifiée (Marlow, 2019). En tant que femmes, elles doivent négocier les normes masculines du secteur formel. En tant que cheffes d’entreprise établies, elles sont en interaction avec les normes féminines survivalistes dotées d’une véritable légitimité dans le pays. Dans ce contexte, comment naviguent-elles entre ces deux régimes de genre ? Notre approche qualitative interprétative met en regard ce que les femmes disent faire pour pérenniser leur activité et comment elles commentent leur action. Nous mettons en évidence le fait qu’elles parviennent à tirer le meilleur parti des deux univers entrepreneuriaux, masculins et féminins. Cette navigation est possible, car elles opèrent un travail approfondi des normes masculines du secteur formel et des normes féminines survivalistes, en y adhérant et en s’en distançant. Dans ce double jeu, elles éprouvent un sentiment d’incongruité et de duplicité vis-à-vis des deux communautés. Cela peut limiter de nombreux échanges, qui leur permettraient de donner plus de sens à ce qu’elles ont entrepris pour nourrir une vision stratégique.
Quand les crises amènent des bifurcations au coeur de l’entrepreneuring : une analyse sensible
Authors: Notais Amélie , Tixier Julie
Published: February 2023

Ce papier explore la dynamique d’entrepreneuring déployée par trois femmes entrepreneures dans les quartiers populaires. Ces femmes vivent de multiples crises (économique, sociale, personnelle…) et suggèrent, par leurs parcours et leurs bifurcations, des moyens pour traverser celles-ci. Le cadre conceptuel de l’entrepreneuring permet de saisir l’énaction et les logiques d’interaction femme-environnement qui modèlent l’entrepreneuring. Nous posons la problématique suivante : comment les femmes traversent-elles des crises multiples en entreprenant ? Au travers des récits des femmes collectés de façon longitudinale, nous donnons à voir les pratiques, les contournements et les bifurcations qu’elles déploient dans une logique rhizomatique au cours de leur chemin entrepreneurial.
Entrepreneuriat au féminin. Le récit ancien d’une ambition bridée
Authors: Lamendour Eve , Robic Paulette
Published: February 2023

Étant donné l’enjeu que représentent les inégalités hommes-femmes dans le travail, interroger les mécanismes du dysfonctionnement de l’entrepreneuriat féminin paraît judicieux. Inscrire cette recherche dans le temps long permet d’étudier les représentations sociales liées à l’entrepreneuriat féminin « en train de se construire et de se diffuser » afin d’en saisir les pesanteurs. Pour cela, nous décidons d’interroger la fiction en tant qu’élément de construction des représentations de l’entrepreneuriat dans la société. Nous convoquons la littérature du xixe siècle, française, anglaise et allemande, pour donner à voir comment se façonnent les identités entrepreneuriales féminines. Notre thèse est que l’ancien récit est toujours à l’oeuvre dans nos sociétés contemporaines, empêchant les femmes de réaliser des carrières de dirigeantes similaires à celles des hommes. Les romans sélectionnés sont traités comme des études de cas à partir desquels nous avons identifié les rôles qu’il était possible de proposer à l’imagination de la lectrice et du lecteur. Nous avons développé le constat que le roman contemporain des révolutions industrielles, en s’intéressant au monde économique, n’a pas dédaigné le rôle des femmes et avons détaillé comment les femmes pouvaient avoir accès à la direction des entreprises, du moins dans la fiction romanesque.
Essai typologique du sens et des causes du suicide des dirigeants-propriétaires de PME en France et en Italie1
Authors: Bah Thierno , Kinowski-Moysan Charlotte , Torrès Olivier , Gaillon Dany
Published: February 2023

Basé sur une étude de cas multiples, cet article porte sur le suicide des dirigeants de PME, un sujet tabou et quasi inexploré par les spécialistes de la PME et de l’entrepreneuriat. Plus précisément, il tente de comprendre le sens et les causes du geste suicidaire chez les dirigeants d’entreprise en mobilisant un double cadre d’analyse : la typologie du suicide du sociologue Baechler (1975) et les stresseurs de l’activité entrepreneuriale de Lechat et Torrès (2016a, 2016b, 2017). Pour cela, l’article propose une démarche méthodologique inédite sur la base de données secondaires portant sur 25 cas concrets de suicide survenus en France et en Italie. Les résultats mettent en lumière le rôle prédominant du surendettement dans les causes profondes qui conduisent les dirigeants à mettre fin à leurs jours. Cependant, tous ne vivent pas la situation de la même façon et ne donnent donc pas le même sens à leur geste suicidaire. Ainsi, différents types de suicides propres aux dirigeants de PME ont été répertoriés au travers de la typologie de Baechler.
Relation d’engagement, risque et stratégies commerciales de la banque : une étude empirique sur des données de PME marocaines
Authors: Hakmaoui Abdelati , Yerrou Hafssa
Published: February 2023

L’objectif de cette recherche consiste à étudier la décision commerciale en termes de disponibilité du crédit prise par les banques marocaines face à des PME présentant des niveaux de risque différents dans le cadre d’une relation d’engagement. En utilisant des données contractuelles sur un échantillon de 512 PME, les tests Logit réalisés nous ont permis de conclure qu’un désengagement accéléré se produit pour les PME à haut risque, qui ont plus d’une banque partenaire et une durée de la relation d’engagement moins longue. La banque marocaine, en accordant des crédits à moyen et long terme à des PME à haut risque, préfère des solutions amicales en consolidant ses engagements ou en accordant des crédits de restructuration dans la perspective d’une évolution favorable du risque de cette catégorie de PME. Pour les PME à bas risque, la stratégie commerciale de la banque favorise le renouvellement avec augmentation des lignes de crédit, particulièrement lorsque la durée de la relation d’engagement est longue et le nombre de banques réduit à une seule banque ou à une banque principale. Plus la durée de la relation et la réciprocité de l’engagement sont élevées, plus la disponibilité du crédit augmente pour les PME avec ce profil de risque.
Propagation characteristics of rotating beams under combined effect of atmospheric turbulence and thermal blooming
Authors: Zhong Zhe-Qiang , Zhang Xiang , Zhang Bin , Yuan Xiao ,   College of Electronics and Information Engineering, Sichuan University, Chengdu 610064, China,   School of Optoelectronic Science and Engineering, Soochow University, Suzhou 215006, China
Published: February 2023

The rotating beam is a beam that is generated by the heterodyne interference of vortex beams with different topological charges, whose intensity and wavefront rotate rapidly with time. Under Taylor’s frozen air hypothesis, such a rotating beam, whose rotating period is much shorter than the characteristic time of atmospheric turbulence and the thermal blooming, can travel through all the inhomogeneities due to its rapid rotation during its propagation in the air. The rotation can contribute to the smooth of the wavefront distortion caused by the atmospheric turbulence and the thermal blooming, and thus improve the beam quality and reduce the centroid drift of the rotating beam in far field. The physical model of rotating beam is established by the heterodyne interference of two vortex beams. Taking the atmospheric turbulence and the thermal blooming effect into consideration, the propagation model of the rotating beam in the air is established by using the split-step Fourier method. For simplicity without loss of generality, the influences of the atmospheric turbulence and the thermal blooming effect on the propagation of rotating beam, are both treated as wavefront screen. The difference is that the wavefront screen of atmospheric turbulence is generated by the Kolmogorov power spectrum, while that of thermal blooming is generated by the fluid mechanics equation. The physical mechanism of how the rotating beam mitigates the atmospheric turbulence and the thermal blooming effect is analyzed in detail, that is, when the rotating speed of laser beam is faster than the airflow, the laser beam can pass through all the inhomogeneous and anisotropic atmosphere in the azimuthal direction within the time interval of airflow. After the laser propagates through the frozen air, the total wavefront distortion in the azimuthal direction becomes centrosymmetric with lower PV value, reducing the beam quality degradation. On the basis, the influence of rotation frequency, power ratio of the sub beams, strength of turbulence and thermal blooming on the propagation characteristics of the rotating beam in atmosphere are analyzed. Within a certain range, as the beam rotation frequency increases, the mitigation effect of the rotating beam on atmospheric turbulence and thermal blooming effects are enhanced. With the increase of turbulence intensity and thermal blooming intensity, the mitigation effect of the rotating beam is weakened but still can maintain well, which can provide reference for the engineering applications of laser beam in atmosphere.
Construction method of hybrid quantum long-short term memory neural network for image classification
Authors: Yang Guang , Chao Su-Ya , Nie Min , Liu Yuan-Hua , Zhang Mei-Ling ,   School of Communications and Information Engineering, Xi’an University of Posts and Telecommunications, Xi’an 710121, China
Published: February 2023

Long-short term memory (LSTM) neural network solves the problems of long-term dependence, gradient disappearance and gradient explosion by introducing memory units, and is widely used in time series analysis and prediction. Combining quantum computing with LSTM neural network will help to improve its computational efficiency and reduce the number of model parameters, thus significantly improving the performance of traditional LSTM neural network. This paper proposes a hybrid quantum LSTM (hybrid quantum long-short term memory, HQLSTM) network model that can be used to realize the image classification. It uses variable quantum circuits to replace the nerve cells in the classical LSTM network to realize the memory function of the quantum network. At the same time, it introduces Choquet integral operator to enhance the degree of aggregation between data. The memory cells in the HQLSTM network are composed of multiple variation quantum circuits (VQC) that can realize different functions. Each VQC consists of three parts: the coding layer, which uses angle coding to reduce the complexity of network model design; the variation layer, which is designed with quantum natural gradient optimization algorithm, so that the gradient descent direction does not target specific parameters, thereby optimizing the parameter update process and improving the generalization and convergence speed of the network model; the measurement layer, which uses the Pauli Z gate to measure, and the expected value of the measurement result is input to the next layer to extract useful information from the quantum circuit. The experimental results on the MNIST, FASHION-MNIST and CIFAR datasets show that the HQLSTM model achieves higher image classification accuracy and lower loss value than the classical LSTM model and quantum LSTM model. At the same time, the network space complexity of HQLSTM and quantum LSTM are significantly reduced compared with the classical LSTM network.
Simplification of Chua corsage memristor and hardware implementation of its neuron circuit
Authors: Guo Hui-Meng , Liang Yan , Dong Yu-Jiao , Wang Guang-Yi ,   School of Electronic Information, Hangzhou Dianzi University, Hangzhou 310018, China
Published: February 2023

The Chua corsage memristor (CCM) is a voltage-controlled locally-active memristor, which has complex dynamic behaviors and potential applications in the field of neuromorphic computing. According to the DC V-I plot, the CCM can be classified as two-lobe, four-lobe, and six-lobe type. By analyzing their non-volatility and local activity, it is found that they have the same locally-active region and a common stable equilibrium. The mathematical models of the three CCMs are simplified based on the mechanism of neuromorphic behavior, namely, local activity. After the model simplification, the absolute value operation disappears, but the locally-active domain remains unchanged. For the simplified CCM, its small-signal equivalent circuit at the locally-active operating point is established, which is consistent with CCMs before being simplified. Hence, the model simplification does not change the small-signal characteristics of CCMs.

To further investigate the application of voltage-controlled locally-active memristor in modeling the neuromorphic behavior of neurons, the simplified CCM model is used to connect a capacitor and an inductor to construct a third-order neuron circuit. By applying theoretical analysis methods such as local activity, edge of chaos, and Lyapunov exponents, we predict the parameter domains where different neuromorphic behaviors are generated. The distribution of neuromorphic behaviors is described on a dynamic map determined by the parameters of applied voltage VD and external inductance L. When the memristor is biased in the locally-active region, the system response changes among resting state, periodic spiking oscillation, and chaotic behaviors.

Finally, according to the simplified CCM mathematical model, the corresponding emulator circuit is designed by using three operational amplifiers, two multipliers, a current conveyor, and several resistors and capacitors. Based on the presented memristor emulator circuit, the hardware implementation of the neuron circuit is given. The experimental results verify the correctness and feasibility of the simplified CCM emulator circuit, and show that the simplified CCM-based neuron circuit can produce a variety of neuromorphic behaviors, including resting state, periodic spiking, chaotic state, bimodal response, periodic oscillation, all-or-nothing phenomenon, and spike clustering phenomenon. We expect that this work is helpful in further studying the mechanism of neuromorphic behaviors of the neuron circuit and its practical applications.
Strain-enhanced thermoelectric properties of Nb-doped SrTiO3 thin films
Authors: Ma Yun-Peng , Zhuang Hua-Lu , Li Jing-Feng , Li Qian ,   State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China
Published: February 2023

The development of high-performance thermoelectric materials can help solve the energy crisis in the future. Thin-film thermoelectric materials can meet the requirement for flexibility of wearable devices while supplying electrical power to them. In this study, high-quality Nb-doped SrTiO3 films (Nb:STO) with different thickness are prepared on SrTiO3 (STO) and La0.3Sr0.7Al0.65Ta0.35O3 (LSAT) substrates by pulsed laser deposition. The surface morphologies, crystal structures, and thermoelectric performances of the films are characterized. The results show that the thermoelectric performance of the strain-free film increase with thickness increasing. The power factor at room temperature increases by 187%. The Seebeck coefficient of the 144 nm-thick Nb:STO/LSAT sample with strain is greatly improved to \begin{document}$265.95\;{\text{μ}}{\rm{V}}/{\rm{K}}$\end{document} at room temperature, which is likely to be due to the strain induced changes in the energy band of the thin film. The improvement of the thermoelectric performances of Nb:STO thin films by strain engineering provides a new approach to improving the thermoelectric properties of oxide thin films.
Bilinearization-reduction approach to integrable systems
Authors: Zhang Da-Jun ,   Department of Mathematics, Shanghai University, Shanghai 200444, China
Published: February 2023

The paper is a review of the bilinearization-reduction method which provides an approach to obtain solutions to integrable systems. Many integrable coupled systems can be bilinearized and their solutions are presented in terms of double Wronskians (or double Casoratians in discrete case). The bilinearization-reduction method is based on bilinear equations and solutions in double Wronskian/Casoratian form. For those integrable equations that are reduced from coupled systems, one can first solve the unreduced coupled system, obtaining their solutions in double Wronskian/Casoratian form, then, implement suitable reduction techniques, so that solutions of the reduced equation can be obtained as reductions of those of the unreduced coupled system. The method proves effective in solving not only classical integrable equations but also the nonlocal ones. The so-called nonlocal integrable equations were introduced by Ablowitz and Musslimani via reductions with reverse-space (or reverse-time, or reverse-space-time). Note that this method particularly provides a convenient bilinear approach to solve nonlocal integrable systems. In this review, the nonlinear Schrödinger hierarchy and the differential-difference nonlinear Schrödinger equation are employed as demonstrative examples to elaborate this method. These two examples will be pedagogically helpful in understanding the reduction technique. The reduction is implemented by imposing suitable constraints on the basic column vectors of the double Wronskian/Casoratian. Realizations of the constraints are converted to solve a set of matrix equations which varies with the constraints. Special solutions of the matrix equations are provided, which are also helpful in understanding the eigenvalue structure of the involved spectral problems corresponding to the considered equations. Other examples include the Fokas-Lenells equation and the nonlinear Schrödinger equation with nontrivial background. Since many nonlinear equations with physical significance are integrable as reductions of integrable coupled systems, the paper provides a review as well as an introduction about the bilinearization-reduction method that can be used to solve these nonlinear integrable models.
Multifaceted roles of aerobic glycolysis and oxidative phosphorylation in hepatocellular carcinoma
Authors: Zhang Ying , Li Wenhuan , Bian Yuan , Li Yan , Cong Lei
Published: February 2023

Liver cancer is a common malignancy with high morbidity and mortality rates. Changes in liver metabolism are key factors in the development of primary hepatic carcinoma, and mitochondrial dysfunction is closely related to the occurrence and development of tumours. Accordingly, the study of the metabolic mechanism of mitochondria in primary hepatic carcinomas has gained increasing attention. A growing body of research suggests that defects in mitochondrial respiration are not generally responsible for aerobic glycolysis, nor are they typically selected during tumour evolution. Conversely, the dysfunction of mitochondrial oxidative phosphorylation (OXPHOS) may promote the proliferation, metastasis, and invasion of primary hepatic carcinoma. This review presents the current paradigm of the roles of aerobic glycolysis and OXPHOS in the occurrence and development of hepatocellular carcinoma (HCC). Mitochondrial OXPHOS and cytoplasmic glycolysis cooperate to maintain the energy balance in HCC cells. Our study provides evidence for the targeting of mitochondrial metabolism as a potential therapy for HCC.
Phenylephrine and Ephedrine for Prevention of Hypotension in Women during Lower Segment Caesarean Section under Spinal Anaesthesia: A Randomised Clinical Study
Authors: Shelke Ulpesh , Yadav Shilpi , Vardhan Vikram , Vyas Varsha , Sadawarte Shailaja , Mulla Salman , Patil Surekha , Vaswani Jayshree P
Published: February 2023

Introduction: Hypotension is the most common serious adverse event associated with Spinal Anaesthesia (SA) and is associated with nausea and vomiting leading to pulmonary aspiration, respiratory depression and cardiac arrest. Phenylephrine (PE) and Ephedrine (EP) are vasopressors commonly used for prevention of hypotension associated with SA. Aim: To compare the efficacy and safety of PE and EP in prevention of hypotension induced by SA in women during Lower Segment Caesarean Section (LSCS) surgery. Materials and Methods: The present randomised clinical study was conducted on 60 women, between 18-36 years of age and a Heart Rate (HR) of 60-100 per minute randomised to receive either 100 mcg Intravenous (i.v.) bolus of PE, or 12 mg i.v. of EP during intrathecal block. Women having intraoperative hypotension were injected additional doses of vasopressor. Cardiovascular parameters were recorded at baseline (before block) and then at 1, 5, 10, 15, 30, 40 and 60 minutes. Further, safety was also assessed based on hypotension events and adverse events reported during immediate postoperative period. Data analysis was done using IBM SPSS 17 and a p-value <0.05 was considered statistically significant. Results: The mean age of the study participants in PE and EP group was 26.67±5.40 and 26.23±4.59 years, respectively. Significant differences were observed between PE and EP groups for change in Systolic Blood Pressure (SBP) after 1, 10, 30, 40 and 60 minutes. Overall, there was a slight fall in SBP with PE, whereas, with EP there was a slight rise in SBP. Also, the Diastolic Blood Pressure (DBP) was maintained with EP throughout the 60 minute period, whereas with PE there was an initial rise in DBP followed by a slight fall in DBP. The Mean Arterial Pressure (MAP) was well maintained with PE throughout, whereas with EP there was a fall in MAP after 15 minutes. However, these changes were not clinically significant. The Pulse Rate (PR) was lower with PE compared to EP group at time points of 1, 5, 15 and 20 minutes. The mean respiratory rates and blood oxygen saturation were similar with PE and EP administration (p>0.05). A total of 13 (43.3%) patients in the PE group and 14 (46%) in the EP group had adverse events excluding hypotensive patients. Conclusion: According to the findings of the present study, the i.v. bolus of 100 mcg PE and 12 mg EP administered immediately after SA are equally effective in prevention of maternal hypotension and do not cause any significant cardiovascular and respiratory effects.
Risk Factors of Acute Malnutrition among Children Under Five Years of Age
Authors: Alflah Yousef M. , Alrashidi Mohammed A.
Published: February 2023

Childhood malnutrition remains a significant global public health concern, and despite numerous advances and improvements in child health care; acute malnutrition among children still one of the main public health challenges in the 21st century, particularly in developing countries and is associated with a high risk of morbidity and mortality. Children are the most vulnerable group to the effects of acute malnutrition during the period of their most rapid physical growth and development, because of the extra nutritional requirements for growth and development at this time. Acute malnutrition results from the complex interplay of a range of distal and proximal factors. This review article gives a comprehensive background on the causes of acute malnutrition among children under five years of age.
Review of COVID-19 Management Guidelines
Authors: Singh Akashkumar N. , Singh Nagendra Kumar , Tatineni Swathi
Published: February 2023

The COVID-19 pandemic has adversely affected many countries across the globe both socially and economically and continues to be a major concern to the healthcare system. The majority of the patient groups that were affected were elderly patients and patients with existing co-morbidities such as such as diabetes; hypertension; cardiovascular disease; lung, liver, and kidney disease; cancer patients on chemotherapy; smokers; transplant recipients; and patients taking steroids etc. who were highly vulnerable and susceptible to the infection. Various protective measures such as quarantine from confirmed and suspected cases, nationwide lockdowns, etc., have been implemented in all the affected countries to contain the spread of the virus. Efforts have also been made to develop effective therapeutic strategies to stop the spread of the disease and minimize its high rates of morbidity and mortality especially considering the rapid evolution of the virus giving rise to different variants. A systematic review of the various guidelines published by well-known organizations such as Indian Council of Medical Research (ICMR) and the Ministry of Health (MoH) India and International organizations such as the Infectious Diseases Society of America (IDSA), National Institute of Health (NIH), and World Health Organization (WHO), for the management of COVID-19, was performed and a side-by-side comparison of various important aspects of these guidelines is presented in this review article. The review results showed that, despite minor differences in the terminology used for severity classification, SpO2 levels, quarantine period, and criteria of severity classification these guidelines were mostly similar pertaining to the clinical signs and symptoms of COVID-19, diagnosis and testing criteria, criteria for severity classification, preliminary advice, risk factors, isolation, and methods of prevention of spread – criteria for home quarantine, use of face mask, social distancing, etc. While the majority of the differences noted were mainly in the COVID-19 management strategies and/or treatment recommendations. Overall, besides the limitations, the various guidelines as discussed in this article can still serve as an important tool to healthcare workers and caregivers by providing adequate guidance on the right management of COVID-19 at that time.
RASSF1 is identified by transcriptome coordination analysis as a target of ATF4
Authors: Zhang Youwen , Huynh‐Dam Kim‐Tuyen , Ding Xiaokai , Sikirzhytski Vitali , Lim Chang‐uk , Broude Eugenia , Kiaris Hippokratis
Published: February 2023

Evaluation of gene co‐regulation is a powerful approach for revealing regulatory associations between genes and predicting biological function, especially in genetically diverse samples. Here, we applied this strategy to identify transcripts that are co‐regulated with unfolded protein response (UPR) genes in cultured fibroblasts from outbred deer mice. Our analyses showed that the transcriptome associated with RASSF1, a tumor suppressor involved in cell cycle regulation and not previously linked to UPR, is highly correlated with the transcriptome of several UPR‐related genes, such as BiP/GRP78, DNAJB9, GRP94, ATF4, DNAJC3, and CHOP/DDIT3. Conversely, gene ontology analyses for genes co‐regulated with RASSF1 predicted a previously unreported involvement in UPR‐associated apoptosis. Bioinformatic analyses indicated the presence of ATF4‐binding sites in the RASSF1 promoter, which were shown to be operational using chromatin immunoprecipitation. Reporter assays revealed that the RASSF1 promoter is responsive to ATF4, while ablation of RASSF1 mitigated the expression of the ATF4 effector BBC3 and abrogated tunicamycin‐induced apoptosis. Collectively, these results implicate RASSF1 in the regulation of endoplasmic reticulum stress‐associated apoptosis downstream of ATF4. They also illustrate the power of gene coordination analysis in predicting biological functions and revealing regulatory associations between genes.