bluuebunny/crossref_metadata_2025 huggingface dataset:
Uji Sensitivitas Antibiotik Bakteri ISK Wanita Hamil Di RSIA Siti Khadijah 1 Muhammadiyah Cabang Makassar 2019
Authors: Mangarengi Yusriani , Susilo Wawan , Nulanda Mona , Mokhtar Shulhana , Mustika Mustika
Published: July 2023

Infeksi saluran kemih (ISK) sering terjadi selama kehamilan karena perubahan hormonal dan anatomo-fisiologis yang memfasilitasi pertumbuhan dan penyebaran bakteri di saluran kemih ibu. Diperkirakan bahwa 5-10% wanita mengembangkan beberapa jenis ISK selama kehamilan. Infeksi saluran kemih merupakan salah satu faktor terjadinya persalinan preterm, berat lahir neonatal rendah, kematian janin, preeklampsia. Resistensi antimikroba adalah masalah kesehatan masyarakat yang utama di seluruh dunia, sebagian disebabkan oleh penggunaan antimikroba yang berlebihan. Penelitian ini bertujuan untuk mengetahui sensitivitas antibiotik pada bakteri Infeksi Saluran Kemih terhadap wanita hamil. Sampel urin porsi tengah pada ibu hamil yang digunakan sebagai bahan penelitian. Jenis penelitian ini bersifat true experimental dengan menggunakan metode disk diffusion. Hasil penelitian yang didapatkan antibiotik ampicillin memiliki tingkat sensitivitas terhadap bakteri penyebab ISK sebesar 80,00%, intermediet 0%, dan resisten 20%, antibiotik ciprofloxacin mempunyai tingkat sensitif sebesar 80,00%, intermediet 0%, dan resisten 20,00%, antibiotik cotrimoxazole memiliki tingkat sensitif sebesar 80,00%, intermediet 0%, dan resisten 20,00%. Antibiotik yang baik dan aman digunakan pada ibu hamil dengan infeksi saluran kemih adalah ampicillin. Berdasarkan dari hasil penelitian pada kelima sampel empat diantaranya mendapatkan hasil sensitif. Sebab cipfroloxacin dan cotrimoxazole termasuk kategori C pada FDA yang memiliki risiko terhadap ibu dan janin lebih tinggi dari Ampicillin dengan kategori B.
Hubungan Asupan Makronutrien dan Mikronutrien terhadap Tekanan Darah pada Pasien Hipertensi
Authors: Kurniyanti Novia , Aryanti Aryanti , Makmun Armanto , Nesyana Nesyana , Daeng Kanang Indah Lestari
Published: July 2023

Hipertensi merupakan penyakit degeneratif yang menjadi penyebab tinggi morbilitas dan mortalitas. Prevalensi  hipertensi di Indonesia pun tinggi, selain itu hipertensi sering disebut dengan “the silent killer” karena sering kali tidak terdeteksi. Banyak faktor penyebab terjadinyanya hipertensi, salah satunya adalah faktor kebiasaan mengonsumsi zat gizi yang tidak seimbang. Penelitian ini menggunakan metode narrative review berdasarkan literature atau penelitian yang telah dilakukan dan dipublikasi pada jurnal internasional dan nasional terakreditasi Berdasarkan literature sebanyak 15 jurnal nasional maupun internasional, asupan zat gizi yang dapat meningkatkan tekanan darah adalah karbohidrat  sederhana, protein hewani, lemak, dan natrium, sedangkan asupan  zat gizi  yang  dapat menurunkan tekanan darah adalah karbohidrat kompleks, protein nabati, kalium, magnesium, kalsium, vitamin A, C, D, dan E.
Pengaruh Lamanya Kebiasaan Menggunakan Pantyliner Terhadap Kejadian Fluor Albus Patologis
Authors: Rahmasari Halisa , Yuniati Lisa , Irwan Andi Alamanda , Dewi Anna Sari , Abdi Dian Amelia
Published: July 2023

Fluor albus adalah istilah untuk gejala keluarnya cairan dari genitalia seorang wanita yang bukan darah. Penggunaan pantyliner dengan durasi penggunaan yang lama beresiko terjadinya fluor albus patologis. Dampak penggunaan pantyliner yang dipakai setiap hari ternyata justru dapat mengakibatkan infeksi bakteri atau jamur pada daerah kewanitaan. Hal Ini terjadi karena pantyliner membuat daerah kewanitaan menjadi semakin lembab. Terlalu lama menggunakan pantyliner berbahaya bagi kesehatan organ kewanitaan. Pantyliner yang tidak diganti dalam waktu beberapa jam akan lembab dan menjadi media tumbuhnya jamur atau bakteri.Tujuan dari penelitian ini adalah untuk mengetahui hubungan lamanya kebiasaan menggunakan pantyliner terhadap kejadian fluor albus patologis pada mahasiswi Angkatan 2017 dan 2018. Desain penelitian yang digunakan dalam penelitian ini adalah analitik observasional dengan desain cross sectional. Teknik pengambilan sampel dalam penelitian ini Puposive Sampling. Penelitian ini menggunakan uji Chi-Square.
F3-INTERIOR E-COMMERCE APPLICATION USING 3D VIEW WEBGL REACT THREE FIBER BASED ON ANDROID
Authors: Wicaksono Danang Wahyu , Samsudin Samsudin
Published: July 2023

The development of technology in this era is growing rapidly and has a big effect on the wearer, especially in the world of business. Buying and selling interior furniture manufacturing services is still fairly manual. With the development of information technology, the introduction of interior and exterior furniture can be done using a smartphone or personal computer. People sometimes still experience problems in choosing the right furniture and texture choices. The previous online buying and selling system also lacked the desired texture or color selection, so that orders were still fairly rigid and did not match the wishes of consumers. Based on these problems, this research created an application that can assist consumers in exploring the desired furniture, from setting the color and texture atmosphere. By using WebGl (Web Graphic Library) which makes it easier for consumers to see an overview of interior furniture in the form of a 3D (Three Dimensional) view. but WebGl itself can only be displayed via the website, so the author here will use packages that help React Three Fiber which can render WebGl on Android. The results of this study produce the output of an application that displays 3D on furniture items, which can also change the material texture or color in real-time (real).
Retweet Prediction Based on User-Based, Content-Based, Time-Based Features Using ANN Classification Optimized with the Bat Algorithm
Authors: Rahadian Muhammad Rafi , Jondri Jondri , L Kemas Muslim
Published: July 2023

Twitter is one of the most popular social media platforms today for information dissemination. It is favored by the public due to its real-time information sharing capabilities. Twitter provides two important features for information dissemination: Tweets and Retweets. Tweets allow users to write messages that can be instantly shared. Each tweet can contain text, media such as images, videos, or URLs. Retweets allow users to repost someone else's tweet and distribute it to their own followers. The Retweet feature is considered an effective way to spread information, as a high number of retweets indicates that the information in the tweet is spreading quickly and widely. This research aims to predict retweets based on several features: User-Based Feature, Content-Based Feature, and Time-Based Feature. The classification method used is Artificial Neural Network, which is optimized using a Nature-Inspired Algorithm called Bat Algorithm. The evaluation results of this study show an accuracy of 86%, precision of 87.8%, recall of 93.6%, and F1-score of 90.6% without imbalance class handling. Under Undersampling condition, the accuracy is 80.8%, precision is 91.0%, recall is 81.4%, and F1-score is 85.9%. Under Oversampling condition, the accuracy is 82.4%, precision is 89.6%, recall is 85.6%, and F1-score is 87.5%. These results indicate that using user-based, content-based, and time-based features, applying Artificial Neural Network classification method, and optimizing hyperparameters using Bat Algorithm are effective in predicting retweets.
Evaluation of absorption behavior of Streptozocin anti-cancer drug on Cr doped Carbon Nanotube (5,5) using DFT theoretical method
Authors: Ghasemi Ashraf Sadat , Makiabadi Batoul , Zakarianezhad Mohammad , Ashrafi Fereydoun , Bagheri Poor Mohammad Bagher
Published: July 2023

In this study, the physicochemical characteristics of the adsorption of the anticancer drug Streptozocin (STZ, Zanosar) on the extern surface of Cr-doped carbon nanotube (CNTCr) have been investigated. Optimization all structures were performed using the DFT method at the mpw1pw91/6-311G level of theory. The energies, the highest occupied molecular orbital (HOMO), the lowest unoccupied molecular orbital (LUMO), the density of states (DOS), the distribution of electric charges, and the dipole moments have been calculated to investigate the physical chemistry behaviors of the structures. As well as, the molecular descriptors such as electrophilicity (ω), chemical potential (μ), chemical hardness (h) and chemical softness (S) of compounds were investigated. Examination of the intramolecular and intermolecular bonds indicates that the adsorption of the drug on the nanotube surface has been taking place. Also, the calculated adsorption energy was negative and indicates that the adsorption is thermodynamically possible. All the obtained results of the theoretical calculations have shown that CNTCr is suitable for delivering the anti-cancer drug STZ.
ISLAMIC EDUCATION LEADERSHIP IN BUILDING TOLERANCE OF RELIGIOUS LIFE IN BALUN VILLAGE, TURI SUB-DISTRICT, LAMONGAN DISTRICT
Authors: Ghozali Solchan
Published: July 2023

The research objective is to describe, analyze, and interpret the type of Islamic education leadership in building religious tolerance, the role of Islamic education in building tolerance in religious life, Islamic education leadership models in building tolerance of religious life. This study uses a qualitative approach to the type of phenomenology. Data collection was carried out through in-depth interviews, participant observation and documentation study. Determination of informants was carried out using purposive sampling and snowball sampling techniques. The data analysis technique uses the interactive model analysis technique of Miles and Huberman. While the data validity test technique used triangulation technique. The results of the study answered the focus that the type of Islamic education leadership in building religious tolerance is collaborative-paternalistic-democratic. The paternalistic type referred to is the type of leadership that is fatherly, protective, and educational. Meanwhile, the democratic type is meant to treat everyone equally and to provide opportunities for diverse and diverse communities to actively participate in realizing a harmonious and peaceful religious life. This type of leadership is characterized by the following characters of religious leaders: a) Promoting tolerance and togetherness; b)  Protecting; c) Prioritizing human dignity. The role of the leadership of Islamic education in building tolerance in religious life is as: a) religious experts; b) role models in behavior; c) As well as Mediators. Religious leaders carry out a leadership mechanism in maintaining the socio-cultural system that has survived for decades. Some changes are evolutive. However, for decades, the values of togetherness, harmony and tolerance have been substantively maintained by society. This is inseparable from the leadership role of religious leaders who are united in being committed to maintaining harmony and peace between religious communities. The leadership model of Islamic education is transformational-internal-collective. The transformational leadership model is characterized by several patterns of behavior as follows: a) Implanting trust; b) Civilizing art; c) Maintaining tradition; d) Educating and guiding; and e) Maintaining effective communication. Religious leaders carry out their leadership duties collectively. This means that religious leaders collaborate collegial on it collectively to become joint leaders between religious communities who carry out a common vision of realizing harmonious and harmonious daily lives of citizens. Religious leaders provide charisma, inspiration, intellectual stimulation, and individual consideration that are oriented towards inter-religious harmony by harmonizing religious values while applying the principles of leadership Rasulullah’s style, so that they can manifest themselves as caliphs on earth, who are always committed to carrying out benefit.
THE INTERNAL CONFLICT OF MUSLIMS AND THE URGENCY OF THE MAINSTREAM OF MULTICULTURAL ISLAMIC EDUCATION IN FORMING ISLAMIC UNITY (Case Study of the Shia-Sunni Conflict in Sampang Madura)
Authors: Asrori Muhammad , Maskuri Maskuri
Published: July 2023

After the death of the Prophet Muhammad, the burden of history was borne by Muslims for disputes that started from political issues. The successor to the leadership of the Prophet became the first problem and even became a prolonged problem. Starting from this political dispute, later it will spread to other issues, such as issues of theology and ideology, including the Shia-Sunni intersection which is also a continuation of political problems in the early phase of Islam. Meanwhile, multicultural Islamic education initiated by several Muslim scientists often only discusses the relationship between Islam and other religions. In fact, the problem of internal disputes among Muslims is equally important to be resolved. This study uses qualitative research methods with the type of case study research. The results of the study show the urgency of multicultural education in an effort to re-tighten (taqri@b) Muslims by adhering to the values of multicultural Islamic education. The values of Islamic education include ta'aruf (knowing each other), ta'awun (helping each other), tasamuh (tolerant), tawasuth (moderate), tawazun (harmony), al-'adl (justice) and zuhud.Keywords:Â  Multicultural Islamic Education, ukhuwah Islamiyah, Shia, Sunni.
HARMONIZATION OF ISLAM AND LOCAL TRADITION (Ethnographic Studies in the Construction of Food Culture of the Bawean Telukjatidawang Community)
Authors: Syarifuddin Nur , Cikusin Yaqub
Published: July 2023

Culture is something that will affect the level of knowledge and includes a system of ideas or ideas contained in the human mind in everyday life, There are two things that affect humans in obtaining their culture, namely related to the biological adaptation environment and cultural adaptation. There is an interesting thing when culture is juxtaposed with religion. Culture itself has three values, namely the value of religion, art and solidarity related to taste and hinges on feelings, intuition, and imagination. Expressive culture is generally conservative in character (Sjahbana, 2003: 3).In this context, the food culture of the Bawean community of Telukjatidawang Village can be seen as a religious expression that can be observed sociologically and is the result of community construction. As a belief system, religion is manifested in social systems and behavior by its adherents in public life. Religion is related to human experience both as individuals and groups, so that every behavior he plays is always related to the belief system of the religious teachings he adheres to. Individual and social behavior is driven by internal forces based on the values of religious teachings that were previously internalized in the Bawean community of Telukjatidawang Village. Religion is something that is final, universal, eternal (parennial) and knows no change (absolute). While culture is particular, relative and temporary. Religion without culture can indeed develop as a personal religion, but without culture, religion as a collectivity will have no place (Darori, 2000: 11). Islam responds to local culture, there are traditions wherever and whenever, and is open to accepting local culture, customs or traditions as long as they do not conflict with the spirit of the Qur'an and Sunnah. Likewise with Islam that developed in Bawean society which is very thick with tradition and culture.Â Keywords:Â  Harmonization, Islam, Local Traditions
MULTICULTURAL PAI LEARNING BASED ON ISLAMIC BOARDING SCHOOL WISDOM
Authors: Ratna Dewi A.A. Dyah Ayu
Published: July 2023

Multicultural PAI learning at SMPN 2 Paciran has a distinction with other educational institutions considering that there is a strong element of pesantren wisdom and culture. This is indicated by the addition of several subjects based on the pesantren curriculum of pesantren wisdom which continue to be cultivated in daily interactions in the SMPN 2 Paciran environment. Multicultural PAI learning at SMPN 2 Paciran Lamongan in addition to leading to the learning domain, also tries to shape students into better characters based on the values of pesantren wisdom.

The approach used in this research is qualitative and the type is a case study. Sources of data in this study can be divided into two, namely human (human) and non-human. Analysis of qualitative research data is carried out through three flows of activities that occur simultaneously in the data collection process, namely: data condensation and data presentation (data displays and conclusion drawing/verification). The results of the study stated that the planning carried out by PAI teachers could not be separated from an integrative curriculum with Islamic boarding schools. Where PAI subjects in addition to containing the wisdom of pesantren, also provide local content subjects based on pesantren such as Qur'an Hadith, SKI, Fiqh, and Aqidah Akhlak. Islamic Religious Education teachers in the learning process area are supported by other components such as good mastery of material, choice of methods, use of media, and class mastery. Even though the implementation of learning is the teacher's task, it still requires coordination and assistance from teachers and other school members. PAI teachers practice habituation and examples of Multicultural values based on Islamic boarding school wisdom. Habituation can also be found in some extra activities as well as in daily life. The example of PAI teachers that can be seen in daily life makes students have role models who are close to them. The assessment of multicultural PAI education based on pesantren wisdom uses several standards. Cognitive domains can be identified through tests conducted by the teacher. To find out the affective and psychomotor domains, PAI teachers and local content looked at student behavior in everyday life at school. In addition, students are directed to memorize several letters in the Qur'an. To add and strengthen students' cognitive domains, SMPN 2 Paciran requires students to memorize all Qurâ€™an chapters as a graduation requirement.

Keywords: Learning, Multicultural PAI, Islamic Boarding School Culture
ANATOMICAL, PALYNOLOGICAL AND MICROMOPHOLOGICAL INVESTIGATIONS ON ENDEMIC THYMUS BRACHYCHILUS JALAS (LAMIACEAE)
Authors: ÖZDEMİR Ebru , SÖNMEZ Sefa
Published: July 2023

Objective: In this study, it was aimed to investigate the anatomical and palynological features of endemic Thymus brachychilus Jalas.
Material and Method: The plant material was fixed in 70% alcohol for anatomical investigation. Cross sections of the stem, leaves, and leaf surface sections were stained with sartur solution, and the anatomical aspects were examined. The trichome architectures, mesophyll cells, stomatal index, and glandular and non-glandular trichomes features of leaves and stem have been investigated and compared with the other Thymus species anatomical findings. In addition, measurements of anatomical structures were made. Pollen, flower parts, epidermis and trichome structure of the leaves, were examined in SEM.
Result and Discussion: This is the first anatomical, palynological and micromorphological study on Thymus brachychilus. The epidermis of leaf consists of a single row of elongated shaped cells and is covered with a thin cuticle. There are nonglandular and glandular trichomes in the upper and lower epidermis. Two different types of nonglandular trichomes were found. Stomata are diacytic, and the epidermis is amphistomatic. The mesophyll layer is dorsiventral. The stem cross-section is square. The outermost single-row, elongated, square or rectangular epidermis is covered with a thin cuticle. The pollen symmetry is isopolar, shape is suboblate. It has hexacolpate and bireticulate properties.
Optimalisasi Kinerja Keagenan terhadap Target Muatan Kapal Ro-Ro PT.Atosim Lampung Pelayaran Cabang Semarang
Authors: Amrulloh Adani , Budi Hartanto Cahya Fajar
Published: July 2023

Penelitian ini bertujuan untuk mengetahui penyebab kurangnya muatan dari agen yang mengakibatkan target muatan kapal Ro-Ro milik PT. Atosim Lampung Pelayaran Cabang Semarang tidak terpenuhi dan upaya untuk menanganinya. Selain itu juga untuk mengetahui kendala yang dialami unit muatan dari agen saat proses kegiatan pemuatan kapal Ro-Ro dan penyebab kurangnya pengetahuan dari sopir mengenai proses pemuatan. Metode pengumpulan data dengan observasi di perusahaan, wawancara dengan pihak pimpinan dan operasional perusahaan, dan studi pustaka. Berdasarkan penelitian dapat disimpulkan bahwa PT. Atosim Lampung Pelayaran Cabang Semarang perlu menjalin kerja sama dengan mitra agen agar dalam pemenuhan terget muatan. Selain itu juga perlu menjalin kerja sama dengan para sopir unit kendaraan agar dalam setiap proses pemuatan dapat mengurangi risiko kendala atau hambatan.
BUDAYA KERJA PETUGAS PEMUTAKHIRAN DATA PEMILIHAN KEPALA DESA DI DESA BANYUBANG KABUPATEN LAMONGAN
Authors: Denny Amansyah  , Kushandajani  , Nunik Retno Herawati
Published: July 2023

Tujuan dari penelitian ini adalah untuk mengevaluasi efektivitas komisi pemilihan kepala desa di Desa Banyubang, Kabupaten Lamongan, dan untuk mengidentifikasi hambatan dan faktor pendukung penerapan undang-undang pendaftaran pemilih baru. Dengan menggunakan data primer dan sekunder, metodologi penelitian deskriptif-kualitatif penulis diterapkan dalam penelitian ini. Data kemudian diteliti secara deskriptif dan kualitatif, yaitu semua fakta yang berhasil dikumpulkan penulis sebelum disajikan dalam bentuk kalimat sesuai dengan hasil wawancara dengan sejumlah informan yang telah diidentifikasi sebelumnya. Temuan penelitian ini menunjukkan bahwa meskipun pelaksanaan pemilihan kepala desa di desa Bangyubang telah berjalan efektif, namun belum sepenuhnya efektif. Berikut adalah Jumlah orang yang seharusnya terdaftar untuk memberikan suara dalam suatu pemilihan tetapi tidak menerima pemanggilan untuk melakukan pemilihan, begitu pula sebaliknya, jumlah pemanggilan yang diberikan kepada orang yang lokasinya di suatu daerah tidak diketahui oleh penduduk setempat, sehingga pemanggilan menumpuk begitu saja dan tidak dibaca. Data Kependudukan Potensi Pemilih Pemilihan (DP4), Kurangnya Partisipasi Masyarakat, Anggaran, dan Daerah masing-masing sebagai Faktor Pendukung dan Penghambat. Sumber Daya Manusia (SDM), Loyalitas anggota dan staf PPDP, dan Kerjasama.
Teori Diskursus dan Konseptualisasi Diskursus Lingkungan
Authors: Manarfa La Ode Muhammad Rauda Agus Udaya
Published: July 2023

Karya tulis ini mengupas teori diskursus dan konseptualisasi diskursus lingkungan sebagai pokok permasalahan. Pembahasan teori diskursus dan konseptualisasi diskursus lingkungan ditujukan untuk membentuk pemahaman yang paripurna mengenai diskursus serta konseptualisasinya terhadap lingkungan, melacak pertumbuhan gagasan awalnya, serta mengetahui perkembangannya hingga masa kontemporer. Kajian ini menggunakan pendekatan kualitatif deskriptif, di mana kualitas teori serta interpretasi pencetus teori disajikan secara deskriptif, dipapar, dan dirunut, dan dianalisis menjadi memperjelas diskursus dan konseptualisasinya terhadap lingkungan. Pada hakekatnya wacana memiliki makna yang sama dengan diskursus, sementara diskursus secara harfiah berasal dari kata discourse serta terdapat beberapa ahli seperti Foucault, Laclau & Moffee, Habermas dengan pengarusutamaan diskursus menurut versinya masing-masing. Konseptualisasi diskursus lingkungan antara lain berwujud antroposentrisme, biosentrisme, ekosentrisme, ekofeminisme, institutionalist, bioenvironmentalist, social greens, keanekaragaman hayati (KEHATI), agraria, indigenous people, dan taman nasional.
Analisis keterampilan metakognisi siswa dalam memecahkan masalah Asesmen Kompetensi Minimum (AKM) ditinjau dari gaya kognitif
Authors: Fadilatussyifa Zahwa , Setyaningsih Nining
Published: July 2023

Tujuan penelitian ini adalah untuk menganalisis keterampilan metakognisi siswa kelas VIII A dalam menyelesaikan soal AKM ditinjau dari gaya kognitif. Subjek pada penelitian deskriptif kualitatif ini adalah 2 siswa bergaya kognitif field dependent dan 2 siswa bergaya kognitif field independent dengan objek penelitian sesuai dengan tujuan penelitian. Instrumen yang digunakan adalah soal AKM dengan materi SPLDV dan tes GEFT. Keabsahan data dilakukan dengan teknik triangulasi. Teknik pengumpulan data yang digunakan yaitu tes, wawancara, dan dokumentasi. Teknik analisis data menggunakan tahap reduksi data, penyajian data, dan kesimpulan. Reduksi data diolah dari hasil tes dan wawancara dengan siswa, kemudian dipaparkan dalam bentuk narasi lalu disimpulkan proses metakognisi yang terjadi. Hasil dari penelitian ini yaitu siswa field independent lebih unggul daripada siswa field dependent. Dari soal AKM yang diberikan, menunjukkan siswa field independent cenderung lebih cepat dan mudah dalam memecahkan masalah dengan menguasai empat komponen metakognisi. Sedangkan siswa field dependent belum dapat mengembangkan keempat komponen metakognisi. Siswa field dependent masih dalam tahap menguasai tahap prediksi dan perencanaan saja, sehingga penguasaan siswa field dependent mengalami perbedaan dalam setiap penelitian.
COVID-19 PANDEMİSİ VE ÖNCESİNDE HALKIN FARKLI DUYGU DURUM İFADELERİNE İLGİSİNİN GOOGLE TRENDLER ÜZERİNDEN ANALİZİ
Authors: GÜNDÜZ HOŞGÖR Derya , GÜNGÖRDÜ Hacer , HOŞGÖR Haydar
Published: July 2023

Bu çalışmanın temel amacı Covid-19 pandemisi sırasında ve öncesinde halkın farklı duygu durum ifadelerine yönelik ilgisinde istatistiki olarak anlamlı bir farklılık olup olmadığının incelenmesidir. Çalışmanın verileri ücretsiz ve halka açık bir veri tabanı olan Google Trendler’den elde edilmiştir. Covid-19 öncesi dönemi için Mart 2019-2020 yıl aralığı, pandemi dönemi içinse Mart 2020-2021 dönemi referans alınmış ve 25 adet arama terimi taranmıştır. Tarama işlemi yapılırken Türkiye ve tüm kategoriler seçilerek aramalar yoğunlaştırılmıştır. 20-23 Şubat 2023 tarihleri arasında toplanan verilerin analizinde Student’s t-testi kullanılmıştır. Pandemi öncesi dönemde en fazla arama hacmi ortalamasına sahip olan ilk üç terimin sırayla “ölüm” (81,6), “anksiyete” (79,0), “depresyon” (74,4); pandemi dönemindekilerin ise sırayla “halüsinasyon” (66,9), “anksiyete” (64,9) ve “öfke” (54,9) olduğu saptanmıştır. “Melankoli”, “belirsizlik”, “paranoya” ve “halüsinasyon” terimlerinin Google’da aranma sıklıklarının Covid-19 pandemisi döneminde istatistiki olarak anlamlı derecede (p
DESTEKLEYİCİ ÖRGÜT İKLİMİNİN İŞE ADANMIŞLIK ÜZERİNE ETKİSİNDE PSİKOLOJİK İYİ OLUŞUN ROLÜ
Authors: ASLAN Mecbure , ŞEKER KAYAR Mehtap
Published: July 2023

Bu çalışmanın temel amacı destekleyici örgüt iklimi ve işe adanmışlık arasındaki ilişkide psikolojik iyi oluşun aracılık ve düzenleyicilik rolü olup olmadığını tespit etmektir. Araştırma İzmir ve Adana illerindeki yiyecek-içecek sektöründe faaliyet gösteren orta ve büyük işletmelerdeki çalışanlarla gerçekleştirilmiştir. 397 çalışan, gönüllü olarak araştırmaya katılmıştır. Araştırmada veriler SPSS, AMOS ve Process Macro programları kullanılarak analiz edilmiştir. Ölçeklerin geçerliliğini tespit etmek için doğrulayıcı faktör analizi (DFA) uygulanmış, değişkenler arasındaki ilişkileri belirlemek için de korelasyon analizi yapılmıştır. Araştırmada regresyon analizi ve aracılığı tespit etmek üzere yapısal eşitlik modeli uygulanmış, AMOS programından faydalanılmış, düzenleyici etki için Process Macro kullanılmıştır. Ulaşılan bulgular, algılanan destekleyici örgüt ikliminin psikolojik iyi oluş ve işe adanmışlık üzerinde etkili olduğunu göstermiştir. Bunun yanı sıra destekleyici örgüt iklimi ile işe adanmışlık arasında psikolojik iyi oluşun kısmi aracı olduğu ve düzenleyicilik rolünün bulunduğu görülmüştür.
A Difference-in-Differences Approach for Estimating Survey Mode Effects
Authors: Ollerenshaw Trent
Published: July 2023

A survey’s mode can influence both who takes the survey (selection) and how they respond to its questionnaire (measurement). To distinguish selection and measurement effects, most studies of mode effects use cross-sectional designs. However, cross-sectional designs risk omitted variable bias when the selection process is not fully modeled, but post-treatment bias if the selection process is modeled with variables measured in different survey modes. To address these shortcomings, I propose using difference-in-differences with mixed-mode panel surveys to identify measurement effects. Difference-in-differences compares changes in survey responses over time among panelists who switch modes to panelists who do not switch modes. Difference-in-differences can help reduce omitted variable bias without introducing post-treatment bias. I demonstrate the difference-in-differences approach by estimating the effects of completing live interviews vs. online surveys on the measurement of racial attitudes and political knowledge in the 2016-2020 ANES and cognitive functioning in the 1992-2020 Health and Retirement Study.
Psychobiotics and fecal microbial transplantation for autism and attention-deficit/hyperactivity disorder: microbiome modulation and therapeutic mechanisms
Authors: Kwak Min-jin , Kim Seung Hyun , Kim Hoo Hugo , Tanpure Rahul , Kim Johanna Inhyang , Jeon Byong-Hun , Park Hyun-Kyung
Published: July 2023

Dysbiosis of the gut microbiome is thought to be the developmental origins of the host’s health and disease through the microbiota-gut-brain (MGB) axis: such as immune-mediated, metabolic, neurodegenerative, and neurodevelopmental diseases. Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are common neurodevelopmental disorders, and growing evidence indicates the contribution of the gut microbiome changes and imbalances to these conditions, pointing to the importance of considering the MGB axis in their treatment. This review summarizes the general knowledge of gut microbial colonization and development in early life and its role in the pathogenesis of ASD/ADHD, highlighting a promising therapeutic approach for ASD/ADHD through modulation of the gut microbiome using psychobiotics (probiotics that positively affect neurological function and can be applied for the treatment of psychiatric diseases) and fecal microbial transplantation (FMT).
Written representation of spoken interaction in the official parliamentary transcripts of the Finnish Parliament
Authors: Voutilainen Eero
Published: July 2023

In this article, I will analyze the written representation of spoken interaction in the official plenary session transcripts of the Finnish Parliament. The official parliamentary transcripts are not—and cannot be—identical copies of the original speech event. Instead, they are linguistically and textually edited in many ways. I will examine the different types of editorial changes that are made in the official Finnish parliamentary transcripts. These include phonological, morphological, and syntactic alterations, editing out of self-repairs, planning expressions, stuttering and slips-of-tongue, and finding written ways of expression for phenomena such as pauses, prosody, gestures, and non-verbal events. I will also discuss how the editorial changes affect the written representation of plenary session interaction.
Changing times in the middle of East and West: cultural dispositions three years later
Authors: Pilotti Maura A. E. , Waked Arifi N. M. , El Alaoui Khadija , Abdelsalam Hanadi
Published: July 2023

In the middle of East and West, Saudi Arabia is a society that has been the object of a socioeconomic plan to engineer a sustainable, knowledge-driven, and market-based economy since before the pandemic. The plan, which heavily relies on young college-educated women, requires a traditional collectivistic ethos to adjust to an individualistic one. The pandemic has temporarily interrupted the execution of the plan. The main aim of the present study is two-fold: (a) determine whether female college students’ cultural dispositions and conceptual organization habits (similarity-driven versus function-driven ways of organizing information) have changed after the pandemic and (b) assess whether dispositions and habits contribute to academic attainment (as measured by GPA) differently before and after the pandemic. To this end, through a cross-sectional design, this retrospective study examines the cultural dispositions and conceptual organization habits of a sample of bilingual female college students 3 years apart before and after the pandemic. It finds no differences in conceptual organization habits as a function of time and no relationship between either cultural dispositions or conceptual organization habits and academic attainment. However, horizontal individualism is found to increase after the pandemic as well as to be negatively related to function-driven conceptual organization habits. Although these findings underlie the increasing individualism that accompanies socioeconomic development globally, they question common assumptions of a straightforward link between academic attainment and cultural differences.
Assessing spatial and temporal variation in obligate resprouting, obligate seeding, and facultative seeding shrub species in California’s Mediterranean-type climate region
Authors: Underwood Emma C. , Sorenson Quinn M. , Schrader-Patton Charlie C. , Molinari Nicole A. , Safford Hugh D.
Published: July 2023

Mediterranean-climate region (MCR) shrublands have evolved a set of regeneration strategies in response to periodic, high intensity wildfires: obligate seeding (OS), obligate resprouting (OR), and facultative seeding (FS) species. In the North American MCR, data on their spatial and temporal variability is currently lacking, which is a significant information gap for resource managers. We developed a multinomial model using dynamic and static variables to predict the distribution of the three shrub post-fire regeneration strategies, plus trees and herbs, in southern California. Cross-validation showed 50% of the predicted values for each of the five plant groups were within 8–24 percent of the actual value. We assessed variation in shrub regeneration strategies in three ways. First, we found the three major shrub community types (mixed chaparral, chamise-redshank chaparral, and coastal sage scrub) had proportionally greater biomass of FS (37–43% of total biomass) than OR or OS. Second, we assessed the spatial variability using (a) moisture availability (climatic water deficit and solar radiation) and found FS accounted for an increasingly greater proportion of total aboveground live biomass as water became limited, while OR biomass decreased; and (b) ecosystem productivity (NDVI) which showed the proportion of OS, OR, and tree biomass increased with productivity (with a corresponding dramatic decrease in herb biomass). We also assessed temporal variability using time since fire and found OS represented an initially small proportion of total biomass immediately post-fire (8–10%) which increased with time since fire (13–17%). Third, spatial outputs from the multinomial model indicated FS dominated pixels were most widely distributed across the study area (~3.4 million ha, 71%), compared to OR and OS covering 5% each. FS also occurred more frequently on warmer, south facing slopes and summits whereas OR preferred cooler, north facing slopes and valleys (p < 0.0001). Better understanding the distribution of OS, OR, and FS shrubs is important for resource management, including quantifying shrubland carbon storage and identifying areas for post-fire restoration, as described in a case study of the Bobcat Fire on the Angeles National Forest.
Modelling swell propagation across the Pacific
Authors: Pathirana Sachini , Young Ian , Meucci Alberto
Published: July 2023

Ocean wave swell generated in the vicinity of Campbell Island in the Southern Ocean is tracked along Great Circle paths across the Pacific Ocean. Data from a wave buoy at Campbell Island provides data on the directional spectrum in the generation region. The swell is measured at locations along a series of 19 Great Circle paths across the Pacific using Sentinel-1 SAR and CFOSAT satellite data. The WAVEWATCH III spectral wave model is used as a diagnostic tool to investigate the physical processes active in the swell propagation and decay. The results indicate that present day spectral wave models over-estimate the decay rate of swell. Although these models contain source terms to represent swell decay and negative wind input, these terms still largely remain tuning parameters. The data indicates that further research is required to adequately represent the observed magnitudes of the swell decay. In addition, the data show that currents have only a small impact on the observed swell decay and that islands can have a major impact. Such island impacts are poorly represented by spectral wave models.
A wearable fetal movement detection system for pregnant women
Authors: Qin Manping , Xu Yong , Liang Yubao , Sun Tie
Published: July 2023

A wearable device-based fetal movement detection system for pregnant women is proposed to resolve the problems of low accuracy of fetal movement detection by fetal heart monitor, difficulties of fetal movement monitoring by pregnant women in person, and inability to monitor for long periods of time by ultrasonic Doppler imaging device. The overall software design flow of the system is proposed after determining the overall structure of the system based on symmetric sensor. The application circuit of the three-axis acceleration sensor MC3672 and its supporting sensor data collection program are designed, and the application circuit of the main control chip NRF52840 with Cortex-M4 core is analyzed. The function of data collection and algorithm recognition result transfer to a smartphone is realized through the fetal movement recognition and algorithm design and Bluetooth communication design. Finally, the system test scheme is introduced, which involves performing functional tests on four healthy pregnant volunteers and analyzing the results. The experimental results show that the average recognition rate and correct rate of this system to recognize fetal movement is 89.74% when using the real fetal movement actively perceived by pregnant women as the standard, achieving a domestic and wearable design of fetal movement monitoring device for pregnant women that can be used to analyze and predict the fetal health condition.
Characterization and potential of periosteum-derived cells: an overview
Authors: Cao Rongkai , Chen Beibei , Song Kun , Guo Fang , Pan Haoxin , Cao Yujie
Published: July 2023

As a thin fibrous layer covering the bone surface, the periosteum plays a significant role in bone physiology during growth, development and remodeling. Over the past several decades, the periosteum has received considerable scientific attention as a source of mesenchymal stem cells (MSCs). Periosteum-derived cells (PDCs) have emerged as a promising strategy for tissue engineering due to their chondrogenic, osteogenic and adipogenic differentiation capacities. Starting from the history of PDCs, the present review provides an overview of their characterization and the procedures used for their isolation. This study also summarizes the chondrogenic, osteogenic, and adipogenic abilities of PDCs, serving as a reference about their potential therapeutic applications in various clinical scenarios, with particular emphasis on the comparison with other common sources of MSCs. As techniques continue to develop, a comprehensive analysis of the characterization and regulation of PDCs can be conducted, further demonstrating their role in tissue engineering. PDCs present promising potentials in terms of their osteogenic, chondrogenic, and adipogenic capacities. Further studies should focus on exploring their utility under multiple clinical scenarios to confirm their comparative benefit over other commonly used sources of MSCs.
Cell-specific rates of sulfate reduction and fermentation in the sub-seafloor biosphere
Authors: Jaussi Marion , Jørgensen Bo Barker , Kjeldsen Kasper U. , Lomstein Bente A. , Pearce Christof , Seidenkantz Marit-Solveig , Røy Hans
Published: July 2023

Microorganisms in subsurface sediments live from recalcitrant organic matter deposited thousands or millions of years ago. Their catabolic activities are low, but the deep biosphere is of global importance due to its volume. The stability of deeply buried sediments provides a natural laboratory where prokaryotic communities that live in steady state with their environments can be studied over long time scales. We tested if a balance is established between the flow of energy, the microbial community size, and the basal power requirement needed to maintain cells in sediments buried meters below the sea floor. We measured rates of carbon oxidation by sulfate reduction and counted the microbial cells throughout ten carefully selected sediment cores with ages from years to millions of years. The rates of carbon oxidation were converted to power (J s−1 i.e., Watt) using the Gibbs free energy of the anaerobic oxidation of complex organic carbon. We separated energy dissipation by fermentation from sulfate reduction. Similarly, we separated the community into sulfate reducers and non-sulfate reducers based on the dsrB gene, so that sulfate reduction could be related to sulfate reducers. We found that the per-cell sulfate reduction rate was stable near 10−2 fmol C cell−1 day−1 right below the zone of bioturbation and did not decrease with increasing depth and sediment age. The corresponding power dissipation rate was 10−17 W sulfate-reducing cell−1. The cell-specific power dissipation of sulfate reducers in old sediments was similar to the slowest growing anaerobic cultures. The energy from mineralization of organic matter that was not dissipated by sulfate reduction was distributed evenly to all cells that did not possess the dsrB gene, i.e., cells operationally defined as fermenting. In contrast to sulfate reducers, the fermenting cells had decreasing catabolism as the sediment aged. A vast difference in power requirement between fermenters and sulfate reducers caused the microbial community in old sediments to consist of a minute fraction of sulfate reducers and a vast majority of fermenters.
Ferroptosis and PPAR-gamma in the limelight of brain tumors and edema
Authors: Yakubov Eduard , Schmid Sebastian , Hammer Alexander , Chen Daishi , Dahlmanns Jana Katharina , Mitrovic Ivana , Zurabashvili Luka , Savaskan Nicolai , Steiner Hans-Herbert , Dahlmanns Marc
Published: July 2023

Human malignant brain tumors such as gliomas are devastating due to the induction of cerebral edema and neurodegeneration. A major contributor to glioma-induced neurodegeneration has been identified as glutamate. Glutamate promotes cell growth and proliferation in variety of tumor types. Intriguently, glutamate is also an excitatory neurotransmitter and evokes neuronal cell death at high concentrations. Even though glutamate signaling at the receptor and its downstream effectors has been extensively investigated at the molecular level, there has been little insight into how glutamate enters the tumor microenvironment and impacts on metabolic equilibration until recently. Surprisingly, the 12 transmembrane spanning tranporter xCT (SLC7A11) appeared to be a major player in this process, mediating glutamate secretion and ferroptosis. Also, PPARγ is associated with ferroptosis in neurodegeneration, thereby destroying neurons and causing brain swelling. Although these data are intriguing, tumor-associated edema has so far been quoted as of vasogenic origin. Hence, glutamate and PPARγ biology in the process of glioma-induced brain swelling is conceptually challenging. By inhibiting xCT transporter or AMPA receptors in vivo, brain swelling and peritumoral alterations can be mitigated. This review sheds light on the role of glutamate in brain tumors presenting the conceptual challenge that xCT disruption causes ferroptosis activation in malignant brain tumors. Thus, interfering with glutamate takes center stage in forming the basis of a metabolic equilibration approach.
Combined radiotherapy and immune checkpoint inhibition for the treatment of advanced hepatocellular carcinoma
Authors: Shannon Alexander H. , Manne Ashish , Diaz Pardo Dayssy A. , Pawlik Timothy M.
Published: July 2023

Hepatocellular Carcinoma (HCC) is one of the most common cancers and a leading cause of cancer related death worldwide. Until recently, systemic therapy for advanced HCC, defined as Barcelona Clinic Liver Cancer (BCLC) stage B or C, was limited and ineffective in terms of long-term survival. However, over the past decade, immune check point inhibitors (ICI) combinations have emerged as a potential therapeutic option for patients with nonresectable disease. ICI modulate the tumor microenvironment to prevent progression of the tumor. Radiotherapy is a crucial tool in treating unresectable HCC and may enhance the efficacy of ICI by manipulating the tumor microenvironment and decreasing tumor resistance to certain therapies. We herein review developments in the field of ICI combined with radiotherapy for the treatment of HCC, as well as look at challenges associated with these treatment modalities, and review future directions of combination therapy.
Magneto-thermoelectric effects mapping using tip-induced temperature gradient in atomic force microscopy
Authors: Isshiki Hironari , Budai Nico , Otani YoshiChika
Published: July 2023

Mapping magneto-thermoelectric effects, such as the anomalous Nernst effect, are crucial to optimize devices that convert thermal energy to electric energy. In this article, we show the methodology to realize this based on a technique we recently established using atomic force microscopy, in which a tip contact on the surface locally creates the temperature gradient. We can map the non-magnetic Seebeck and anomalous Nernst effects separately by investigating the magnetic field dependence. The simulation based on a simple heat transfer model between the tip and sample quantitatively explains our results. We estimated the magnitude of the anomalous Nernst effect in permalloy from the experiment and simulation to be ∼0.10 μV/K.
Numerical approximations for fluid flow and heat transfer in the boundary layer with radiation through multiple Lie similarity transformations
Authors: Bilal Muhammad , Safdar Muhammad , Ahmed Shoaib , Kallu Karam Dad , Ali Muhammad Umair , Zafar Amad , Kim Kwang Su , Hyuk Byun Jong
Published: July 2023

The dependent or independent variables of differential equations may be reduced by applying its associated Lie point symmetries. Seven-dimensional Lie point symmetry algebra exists for differential equations representing heat transfer in a boundary layer flow in the presence of radiation. The linear combinations of these seven Lie symmetries are used first to deduce the invariants and then derive the Lie similarity transformations for the original set of partial differential equations (PDEs). This procedure is repeated for the set of transformed equations to further reduce the system of PDEs into the system of ordinary differential equations (ODEs). Multiple exact similarity transformations are obtained using this procedure. All these transformations map the system of three PDEs with three independent variables of flow and heat transfer under the specified set of conditions into two-dimensional systems of equations with only one independent variable, the system of ODEs. Approximate solutions for these reduced systems are established using the finite difference method to illustrate the effects of unsteadiness, Prandtl number, and radiation on the boundary layer thickness, flow, and heat transfer. This type of study was conducted under the effect of these parameters previously with a different set of similarity transformations. However, the Lie similarity transformations deduced in this work, which have not been employed, lead to different types of reduced systems of ODEs, thereby providing different velocities and temperature profiles and providing valid solutions for previously unexplored regions for unsteadiness in the fluid flow and heat transfer. Some of these transformations and their resulting systems provide results that contradict the flow and heat transfer in real fluids.