bluuebunny/crossref_metadata_2025 huggingface dataset:
Primary care networks as a means of supporting primary care: findings from qualitative case study-based evaluation in the English NHS
Authors: Checkland Kath , Bramwell Donna , Warwick-Giles Lynsey , Bailey Simon , Hammond Jonathan
Published: November 2023

Objectives

This study aimed to evaluate primary care networks (PCNs) in the English National Health Service. We ask: How are PCNs constituted to meet their defined goals? What factors can be discerned as affecting their ability to deliver benefits to the community, the network as a whole and individual members? What outcomes or outputs are associated with PCNs so far? We draw policy lessons for PCN design and oversight, and consider the utility of the chosen evaluative framework.

Design and setting

Qualitative case studies in seven PCN in England, chosen for maximum variety around geography, rurality and population deprivation. Study took place between May 2019 and December 2022.

Participants

PCN members, staff employed in additional roles and local managers. Ninety-one semistructured interviews and approximately 87 hours of observations were undertaken remotely. Interview transcripts and observational field notes were analysed together using a framework approach. Initial codes were derived from our evaluation framework, with inductive coding of new concepts during the analysis.

Results

PCNs have been successfully established across England, with considerable variation in structure and operation. Progress is variable, with a number of factors affecting this. Good managerial support was helpful for PCN development. The requirement to work together to meet the specific threat of the global pandemic did, in many cases, generate a virtuous cycle by which the experience of working together built trust and legitimacy. The internal dynamics of networks require attention. Pre-existing strong relationships provided a significant advantage. While policy cannot legislate to create such relationships, awareness of their presence/absence is important.

Conclusions

Networked approaches to service delivery are popular in many health systems. Our use of an explicit evaluation framework supports the extrapolation of our findings to networks elsewhere. We found the framework to be useful in structuring our study but suggest some modifications for future use.
Regional variation in the use of revascularisation for peripheral artery disease in Japan: a cross-sectional observational study
Authors: Kanda Masato , Kuwabara Hiroyo , Kitahara Hideki , Kobayashi Yoshio , Inoue Takahiro
Published: November 2023

Objectives

We aimed to investigate the regional variations in the number of interventions and surgeries for peripheral artery disease (PAD) and explore the major determinants of the variations.

Design

Cross-sectional study.

Setting

The Japanese Ministry of Health, Labour and Welfare National Database and Diagnostic Procedure Combination database in 2018.

Data

The rates of endovascular treatment (EVT), bypass surgery per 100 000 individuals in the population were calculated for all 47 prefectures in Japan. The total annual changes in the rates of EVT and bypass surgery in Japan from 2012 to 2019 were calculated.

Analysis

A linear regression model was developed with rates of EVT and bypass surgery as dependent variables and regional medical supply in each prefecture as explanatory variables. These regional factors included the rate of percutaneous coronary intervention (PCI) for angina, the numbers of cardiovascular specialists, specialists in cardiac surgery, interventional radiology (IVR) training facilities and cardiovascular surgery training facilities, per 100 000, respectively.

Results

There was a 5.7-fold difference (143 and 25 per 100 000 individuals aged ≥40 years) in the highest and lowest EVT rates. The highest and lowest rates of bypass surgery were 34 and <10 per 100 000 individuals aged ≥40 years in a prefecture, respectively. The rate of PCI contributed most significantly positive to the rate of EVT (p<0.001). However, the numbers of IVR and cardiovascular surgery training facilities had significant positive and negative relationships, respectively, with the rate of EVT. The numbers of specialists in cardiac surgery and cardiovascular specialists had significant positive (p=0.01) and negative (p=0.01) correlations, respectively, with the rate of bypass surgery.

Conclusions

Considerable regional variations in the rates of revascularisation for PAD were found. Unbalanced presence of medical resources, preference of suppliers and the training system had larger effects on the regional variation in Japan.
Responses of maize root morphology and soil available nutrient to fertilizer types in a coal mine reclamation area
Authors: Huijuan Bo , Xu Minggang , Dongsheng Jin , Qiang Zhang
Published: November 2023

The impact of different fertilizer types with equal nitrogen levels on maize root morphology and soil available nutrient is needed, especially in coal mine reclamation areas. After 9-year fertilization, the maize root biomass, length, and surface area of the organic–inorganic fertilization (OF) treatment were significantly higher than those of other treatments. The contents of available phosphorus and available potassium were 18.46 and 176 mg·kg−1, respectively, under OF treatment, which were significantly higher than those under other treatments. Our findings indicate that the fertilizing effect of OF treatment is effective for soil reclamation in mining areas.
Structure, acidic properties and the coordination ability of sapphyrin with an unsymmetric substitution system
Authors: Ivanova Yulia B. , Pukhovskaya Svetlana G. , Lukanov Mikhail M. , Semeikin Aleksandr S. , Vashurin Arthur S. , Syrbu Sergey A.
Published: November 2023

Synthesis of unsymmetrically substituted 2,3,7,13,16,17,22,23-octamethyl-8,12-di-[Formula: see text]-butylsapphyrin dichloride (H5P[Formula: see text]Cl[Formula: see text] was carried out. The synthesized compound was identified by electron absorption, 1H NMR spectroscopy, and mass spectrometry. The stability of the anionic complex and the acidic properties of H5P[Formula: see text]Cl2 were studied by spectrophotometric titration. The parameters of the electronic absorption spectra and the concentration range for the existence of deprotonated forms, as well as their acid dissociation constants, are determined. The geometric structure and electronic structure of the molecular and ionic forms of the resulting sapphyrin were calculated in terms of the density functional theory (B3LYP/Def2TZVPP with an empirical correction for GD3 dispersion). The calculations showed good agreement with the experimental data.
A Conversation with Ken Holstein: Fostering human-AI complementarity
Authors: Anjum Bushra
Published: November 2023

Ubiquity's senior editor Dr. Bushra Anjum chats with Ken Holstein, an assistant professor at Carnegie Mellon University, where he leads the Co-Augmentation, Learning, & AI (CoALA) Lab. We discuss how, amidst all of the current AI hype, human ability and expertise remain underappreciated. Designing for complementarity in AI-augmented tooling ensures that domain-specific worker-facing AI systems are designed to bring out the best of human ability rather than simply attempting to, many a time incorrectly, automate them away.
Challenges in the New Economy: A New Era for Work Design
Authors: Fraccaroli Franco , Zaniboni Sara , Truxillo Donald M.
Published: November 2023

Models of work design emerged in the twentieth century to address workplace changes created by the industrial revolution. However, the world of work is currently undergoing a new, profound revolution in terms of technological, demographic, and environmental changes, leading to a new economy, within which organizations and employees must function. The field of work design currently includes robust theories with a deep understanding of how work design affects employee outcomes, many with relevance to this new economy. However, the new economy also includes issues never before considered (e.g., algorithmic management and gig and lone work), and the field of work design must tackle the implications of these emerging issues. In this article, we review the general findings on work design and then examine a range of contextual, economic, technological, and diversity issues and their relevance to work design. We conclude with an agenda for future work design research and implications for work analysis and work design interventions and policies.
COVID-19, HIV, and Cryptococcal Meningitis Coinfections with Abnormal Laboratory Findings
Authors: Aghamali Mina , Kazemi Abdolhassan , Asgharzadeh Mohammad , Kafil Hossein Samadi
Published: November 2023

Background. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first introduced in China in 2019, and it has rapidly spread all around the world. Cryptococcus neoformans is the leading cause of fungal meningitis in human immunodeficiency virus- (HIV-) infected patients. A variety of laboratory tests have been introduced for rapid diagnosis of meningitis. Methods. Here, we report a case of coinfection with COVID-19 and cryptococcal meningitis in a HIV-positive patient with abnormal laboratory findings. In this case, COVID-19 was positive by polymerase chain reaction (PCR) and computerized tomography (CT) scan diagnosis. Cryptococcal antigen testing of CSF was negative, whereas India ink staining and cerebrospinal fluid (CSF) culture confirmed the presence of C. neoformans. Results. Although the patient was in a critical stage of illness, serum and CSF levels of procalcitonin were abnormally low, within normal limits. On the other hand, although initial lumbar puncture had showed elevated protein level, the repeat CSFs presented remarkably reduced protein levels. Our findings indicate that despite COVID-19 infection, procalcitonin level may remain normal in HIV-associated cryptococcal meningitis, and findings of an apparently normal procalcitonin level should not exclude the possibility of infection. Also, antigen testing may present false-negative result, and it should not be the sole laboratory method for diagnosis of infectious meningitis. Consequently, CSF culture and staining is recommended, even when antigen testing of organism is negative and CSF profile is unremarkable. Conclusion. Laboratory information should be combined with a good understanding of clinical manifestations of patient to determine if meningitis is present and confirmed COVID-19 should not ignore possibility of other infections for consideration.
Evaluation of Silver Nanoparticles Based on Fresh Cocoa Pods (Theobroma Cacao) Extracts as New Potential Electrode Material
Authors: Somba Alex Vincent , Njanja Evangéline , Deffo Gullit , Fotsop Cyrille Ghislain , Yemele Tajeu Kevin , Tchangou Njiemou Armel Florian , Eya’ane Meva François , Kamgaing Theophile
Published: November 2023

This work focuses on the synthesis of silver nanoparticles using fresh cocoa pods from the “Theobroma cacao” extract plant through the reduction of silver ions (Ag+) into Ag (0) by a green chemistry process, subsequently used as an electrode material. Reaction factors such as pH, incubation time, and silver ion concentration were optimized during the formation of nanoparticles. The synthesized nanoparticles were characterized by ultraviolet spectrophotometry (UV-Vis), Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), and energy dispersive X-ray spectrometry (EDX) analysis. Once drop coating was applied on the glassy carbon electrode (GCE), the resulting film was characterized using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The results show that silver nanoparticles have been well synthesized and can find applications as electrode materials for simultaneous determination of ascorbic acid and uric acid in aqueous solution.
Quantifying Ventilation Design, Room Layout, and Occupant Activity Parameters during Aerosol-Generating Medical Procedures in Hospitals
Authors: Christianson Cole D. , Baylis Jared B. , Komisar Vicki , Brinkerhoff Joshua
Published: November 2023

The risk of airborne disease transmission in hospital rooms during aerosol-generating medical procedures is known to be influenced by the size of the room, air ventilation rate, input-to-output flow ratio, vent surface area, and vent location. However, quantitative recommendations for each ventilation design parameter are scarce. Moreover, room layout and occupant activity parameters, such as furniture locations and healthcare worker movement, are often omitted from studies on airborne disease transmission in hospital settings. As a result, the development of policies and technologies aimed at mitigating airborne disease transmission in hospitals has been limited. To address this shortfall, this study is aimed at first characterizing existing ventilation, room layout, and occupancy parameters in hospital rooms where aerosol generation medical procedures (AGMPs) occur and then testing the hypotheses that ventilation, room layout, and occupancy parameters vary significantly between hospital rooms and, in some cases, with time. Information on AGMPs was collected via a survey circulated to healthcare workers within British Columbia’s Interior Health Authority (IHA), while hospital room and ventilation system information was collected by reviewing drawing packages of 37 IHA hospital rooms. The survey results indicate that AGMPs commonly occur in trauma, ICU, or general ward rooms with positive or negative pressure ventilation systems. Statistical tests, with room type (trauma, ICU, or general), room pressure (positive or negative), and/or time as independent variables, show that variables relating to ventilation (number of supply vents, supply and exhaust vent location, ventilation rate, and supply and exhaust area) and room layout (congestion score, room volume, light area, and number of lights) vary with room type but not with room pressure. Occupant activity variables (number of workers, number of moving workers, and speed score) also vary with room type, although to differing extent with room pressure and time. The survey and drawing review data presented in this study can help guide systematic comparisons of mitigative technologies as well as parametric investigations on how room layout, ventilation, and operational parameters influence airborne disease spread. This is a crucial first step in achieving quantitative and clinically relevant recommendations for mitigating airborne disease transmission in healthcare settings.
Angiographic and Clinical Impact of Novel Revascularization for Occluded Femoropopliteal Prosthetic Bypass Graft: A Combination of Surgical Thrombectomy and Drug-Coated Balloon Angioplasty
Authors: Takei Tatsuro , Kajiya Takashi , Yamamoto Keisuke , Takaoka Junichiro , Atsuchi Yoshihiko , Atsuchi Nobuhiko
Published: November 2023

Background. Previous reports have revealed various endovascular intervention techniques for prosthetic femoropopliteal bypass occlusion (PFPBO); however, treatment for PFPBO remains challenging for most interventionalists and vascular surgeons because the procedure is complicated. Most of the reported techniques involve device implantation. In the present study, we performed a combination of surgical graft thrombectomy and drug-coated balloon angioplasty for PFPBO without implanting any additional devices. Furthermore, we determined the favorable long-term results of this treatment using follow-up angiography. Case Presentation. A 77-year-old man with a history of chronic kidney disease and coronary artery disease presented to our clinic with rest pain on his left leg. Seven years prior to the current consult, he underwent femoropopliteal bypass (FPB) surgery using a prosthetic graft due to in-stent occlusion of the left superficial femoral artery (SFA). Four years after surgery, a duplex ultrasound scan revealed stenosis of the proximal anastomosis site; hence, medical therapy was continued. On the current consult, diagnostic angiography revealed occlusion of the FPB and infrapopliteal vessels. In the first attempt at recanalization, the guidewire was unable to pass through the occluded SFA. Therefore, another technique was performed to revascularize the FPBO and infrapopliteal vessels. We obtained an angiography of the left leg after inserting the guiding sheath via the right common femoral artery (CFA). First, surgical thrombectomy using a Fogarty catheter via the exposed left CFA was performed. Following endovascular therapy via the right CFA, we performed drug-coated balloon angioplasty for anastomotic stenosis and recanalized occlusive infrapopliteal vessels. Restenosis was not observed on follow-up angiograms. On further follow-up angiography, there was notable regression of the residual stenosis at the proximal anastomosis of the prosthetic graft. Conclusion. This novel revascularization strategy may be a viable treatment option for PFPBO.
Cardiovascular Disease Risk Scores and Incident Dementia and Cognitive Decline in Older Men and Women
Authors: Vishwanath Swarna , Hopper Ingrid , Chowdhury Enayet , Wolfe Rory , Freak-Poli Rosanne , Reid Christopher M. , Tonkin Andrew M. , Murray Anne M. , Shah Raj C. , Chong Trevor T.-J. , Woods Robyn L. , McNeil John , Orchard Suzanne G. , Nelson Mark R. , Steves Claire J. , Ryan Joanne
Published: November 2023

Introduction: Risk factors for cardiovascular disease (CVD) also increase the risk of dementia. However, whether commonly used CVD risk scores are associated with dementia risk in older adults who do not have a history of CVD, and potential gender differences in this association, remains unclear. The aim of this study was to determine whether CVD risk scores are prospectively associated with cognitive decline and dementia in initially healthy older men and women. Methods: A total of19,114 participants from a prospective cohort of individuals aged 65+ years without known CVD or dementia were recruited. The atherosclerotic cardiovascular disease risk score (ASCVDRS), Systematic Coronary Risk Evaluation 2-Older Persons (SCORE2-OP), and the Framingham risk score (FRS) were calculated at baseline. Risk of dementia (according to DSM-IV criteria) and cognitive decline (defined as a >1.5 standard deviation decline in global cognition, episodic memory, psychomotor speed, or verbal fluency from the previous year) were assessed using hazard ratio. Results: Over a median follow-up of 6.4 years, 850 individuals developed dementia and 4,352 cognitive decline. Men and women in the highest ASCVDRS tertile had a 41% (95% CI 1.08, 1.85) and 45% (1.11, 1.89) increased risk of dementia compared to the lowest tertile, respectively. Likewise, men and women in the highest SCORE2-OP tertile had a 64% (1.24, 2.16) and 60% (1.22, 2.11) increased risk of dementia compared to the lowest tertile, respectively. Findings were similar, but the risk was slightly lesser when examining risk of cognitive decline for both ASCVDRS and SCORE2-OP. However, FRS was only associated with the risk of cognitive decline among women (highest vs. lowest tertiles: 1.13 [1.01–1.26]). Conclusion: These findings suggest the utility of the ASCVDRS and SCORE2-OP in clinical practice, to not only assess future risk of CVD, but also as potential early indicators of cognitive impairment, even in relatively healthy older men and women.
Immunohistochemical Expression of Insulin-Like Growth Factor-1 Receptor and Its Association with Clinicopathological Parameters in Hepatocellular Carcinoma
Authors: Peloso Maia Maria Luiza , Albuquerque Ronniel Morais , do Carmo Silva Serena Dafne , Lima Cristiano Xavier , Costa Diniz Paulo Henrique , Vieira Teixeira Vidigal Paula
Published: November 2023

Introduction: Hepatocellular carcinoma (HCC) carcinogenesis is not yet fully known. Insulin-like growth factor-1 receptor (IGF-1R) can translocate to the nucleus and modulate cellular growth, possibly participating in HCC development and aggressiveness. This study aimed to evaluate the immunoexpression of IGF-1R in HCC, the cellular compartment involved, and its association with clinicopathological parameters and clinical outcomes. Methods: Liver specimens from 111 HCC patients who underwent liver transplantation or partial surgical resections at a Brazilian referral hospital center were studied. IGF-1R expression was determined by immunohistochemistry, clinical data were collected from medical records, and pathological parameters were obtained from path review. Results: IGF-1R nuclear expression was higher in the tumor than in the adjacent cirrhosis (p < 0.001). The odds of IGF-1R expression in the nucleus compared to the membrane are lower in the cirrhosis condition than in the tumor, suggesting an increase in the prevalence of nucleus expression relative to the membrane from cirrhosis to tumor. There was an association between IGF-1R nuclear expression in HCC and the moderate/poor grade of histologic differentiation (p < 0.001). However, long-term clinical outcomes were not associated with IGF-1R nuclear expression. Conclusion: The data presented here suggest the role of IGF-1R in HCC progression and carcinogenesis as its expression increases in the nucleus relative to the membrane, from cirrhosis to tumor, and it was associated with a poorer differentiated tumor grade. Further research is awaited to fully understand the mechanisms underlying this association.
Entrepreneurial Storytelling: Influencing Consumer Behaviour Through Compelling Narratives
Authors: Nuralam Inggang Perwangsa , Nazil Muhammad
Published: November 2023

The digital era has caused a profound change in the paradigm of corporate interaction with consumers. These changes cover how companies communicate, understand, and respond to customer needs. Storytelling can facilitate more positive and meaningful interactions between companies and customers in the digital world. In summary, narrative storytelling significantly influences sustainable entrepreneurship in emerging markets. The creative and authentic use of narratives told and shared allows for the formation of strong bonds between companies and customers. This can motivate customers to take certain actions, such as making a purchase, sharing a story with others, or participating in further interactions with the brand. Remember that as emotional creatures, humans generally respond more positively to messages that evoke emotion. This is why storytelling, which is focused on the emotional aspect, is very effective. Customers want involvement in stories that have an emotional impact, not just being the target of generally monotonous advertising messages. These changes also push companies to seek new communication methods with their audiences. It is where storytelling platforms and channels play a crucial role. Social media is the most common platform that can be used due to its various models (Facebook, Instagram, Twitter, and Linkedin). Interestingly, some companies are starting to communicate with customers through storytelling, which is shown in the form of short videos or blog reviews. Recent podcasts and live streaming are among the increasingly popular platforms used as storytelling media. It indicates that the company's creativity is being tested, especially in building strong bonds between brands and customers.
THE FUTURE OF CONSUMER BEHAVIOUR: EMERGING TRENDS AND OPPORTUNITIES FOR ENTREPRENEURS
Authors: Nuralam Inggang Perwangsa , Ojuni Ochan Dorgi
Published: November 2023

Changes in consumer behavior are always interesting to discuss because they are directly related to a company's success in business. The transformation that occurs has a significant impact on every consumer behavior. It is still clear in my memory before 2000 physical stores dominated. Now, without coming in person, consumers can already make purchases. Technology does play a big role in influencing consumer behavior. In an era dominated by technology, rapid changes in consumer behavior and developments in digital technology have played a key role in changing the way companies interact with customers. Easy access to mobile devices and the internet have become an integral part of everyday life, enabling consumers to search for information, shop and communicate with brands at various times and locations. One of the market segments that is growing in size at the moment is Generation Z, often referred to as "iGen". Generation Z, who grew up in the digital age, has unique preferences when it comes to shopping and interacting with brands. Generation Z tends to trust product reviews from their fellow generations more than brand advertisements. They often look for product reviews online through platforms like YouTube, Instagram, or dedicated product review websites. This behavior gave rise to a new trend in the world of marketing, namely influencer-focused marketing strategies and user-generated content (User-Generated Content or UGC) which have become increasingly dominant in reaching consumers in the modern era. UGC's credibility is often considered higher than brand-generated content, as it comes from the real experiences of users. It is not surprising that consumers in the future will be more active as marketers for the products they use.
SUSTAINABLE SUPPLY CHAIN: HOW MIS CAN HELP ASSESS AND ACHIEVE EFFICIENCY AND EFFECTIVENESS FOR
Authors: Ramadhan Hanifa Maulani , Haidir Vieri Ahmad
Published: November 2023

Various explanations and ideas of Supply Chains (SC) and Supply Chain Management (SCM) have emerged owing to the rise in global sourcing since the 1980s. Manufacturers agree that a solid Supply Chain and efficient resource allocation are crucial after the COVID-19 pandemic. Consumers and producers are more aware of their products' environmental implications. The environment and society are threatened by population growth and economic activity. Circular Economy (CE) concepts like logistics, vendor management, and resource mapping can boost an organization's performance. The relationship between CE and SCM can be understood in several ways, one of which is Sustainable Supply Chain Management (SSCM). SSCM adds social and environmental factors to supply chain procedures, increasing a company's long-term success. Before utilizing SSCM, focus organizations must create an effective information process method to address supply chain uncertainty, hazards, and information-sharing questions. Digitization and circular development can give manufacturers long-term benefits. Information Digital and Technology (IDT) was first used in supply chain management with EDI, ERP, and computer-aided technologies. AI, IoT, BDA, Cloud, and Blockchain Technology (BT) have gained traction as IDT that could improve SSCM today. Environmental challenges that may affect human cultures and well-being are significant concerns as Food Supply Chains (FSC) expand to satisfy seasonal food demand, sustainability, and safety. As a result, the meaning of SSCM has emerged in recent years to address the growing concern over sustainability in the FSC. FSC was made more sustainable by measures such as the use of technology, improved resource effectiveness, staff education, and a better knowledge of customer demand.
Sinais de pontuação desacompanhados em quadrinhos
Authors: Kleppa Lou-Ann
Published: November 2023

Ponto de interrogação, ponto de exclamação e reticências são sinais de pontuação que podem ocorrer isoladamente (em balões de fala, balões de pensamento ou ancorados na imagem) nos quadrinhos. Nosso corpus principal é formado pelas tirinhas de Yehuda Moon & the Kickstand Cyclery porque notamos um uso constante desses sinais de pontuação desacompanhados. Como contraponto, recorremos a The essential Calvin and Hobbes (1988) de Bill Watterson e Deus 1, 2 e 3 de Laerte. Contrastando esses corpora, perceberemos preferências pontuatórias. Cohn (2013) concebe esses sinais desacompanhados como upfixes (afixos), o que colocamos em discussão com base na formalização dos sinais de pontuação de Dahlet (2002; 2006) e Kleppa (2023) e na concepção de multimodalidade dos quadrinhos de Gedin (2019).
Cronologia dos quadrinhos de Ciça na imprensa brasileira
Authors: Ramos Paulo , Carmelino Ana Cristina
Published: November 2023

Propõe expor e documentar a trajetória dos quadrinhos produzidos por Ciça, uma das primeiras artistas a produzir tiras cômicas nos jornais brasileiros. A importância histórica da autora contrasta com a falta de uma cronologia detalhada de sua atuação na imprensa, lacuna que este estudo pretende preencher. Os resultados mostram que os trabalhos gráficos dela perpassam décadas e não se resumem à sua série mais conhecida, O Pato.
Desavenças, golpes e navalhas: a capoeira nos quadrinhos o Cortiço
Authors: Silva Robson Carlos
Published: November 2023

Apresenta análises da história em quadrinhos O Cortiço, de Rodrigo Rosa e Ivan Jaf, adaptada do romance homônimo de Aluísio Azevedo, que versa sobre tramas da vida cotidiana das gentes simples e humildes do nosso povo, vivendo em um cortiço no Rio de Janeiro do século XIX. O objetivo central é compreender os sentidos atribuídos ao personagem Firmo, envolvido em desavenças e disputas em torno do amor da Rita Baiana, tendo a capoeira como pano de fundo. O estudo, de abordagem qualitativa, utiliza técnica analítica com texto e imagem (Bauer; Gaskell, 2014) dialogando com os estudos de Postema (2018). Os resultados apontam para a construção de sentidos positivos acerca de um personagem negro e capoeirista em quadrinho nacional, abordando com maestria a dinâmica histórica e as relações humanas da época representada, onde a capoeira impera como cultura de afirmação do povo negro.
O que a Evolução pode nos ensinar sobre Raça e Racismo? Entrevista com o Joseph L Graves Jr.
Authors: Salles Eyshila Leticia Nunes , Andrade Rogério Cleiton de , Blumrich Lukas
Published: November 2023

O Dr. Joseph L. Graves Jr., renomado biólogo evolutivo e geneticista norte-americano, da North Carolina A&T State University, concedeu uma entrevista à Revista de Medicina, através dos grupos de pesquisa Race.ID (Grupo de Pesquisa em Saúde da População Negra) e BrEHS (Brazilian Evolution and Health Study Group). Na entrevista, o professor conta sobre sua trajetória, os desafios enfrentados na carreira, o que significa ser um cientista negro nos EUA, as complicadas relações entre a medicina e a ideia de raça e o que a medicina evolutiva tem a ver com tudo isso.
Efeitos cardiovasculares de linalol livre ou complexado à β-ciclodextrina: um foco para ação anti-hipertensiva
Authors: Brito Daniele Santana de , Moraes Raiana dos Anjos , Jesus Rafael Leonne Cruz de , Araújo Fênix Alexandra de , Silva Liliane Barreto da , Lima Gabriela Brandão de Carvalho , Camargo Samuel Barbosa , Silva Isnar Lima Pereira da , Silva Darízy Flávia
Published: November 2023

Introdução: O monoterpeno linalol (LIN) apresenta várias atividades farmacológicas, inclusive como anti-hipertensivo, porém, apresenta problemas de solubilidade devido ao seu caráter lipofílico. Dessa forma, estratégias de estabilização e melhoria de parâmetros farmacocinéticos e farmacodinâmicos vem sendo estudadas, como a formação de complexos de inclusão com ciclodextrinas (CDs). Objetivo: O objetivo desta revisão é reunir informações sobre os efeitos cardiovasculares do LIN e avaliar a possibilidade do uso de CDs para melhorar as propriedades biológicas do LIN. Metodologia: Esta revisão de literatura abrangeu artigos no período entre 1998 e 2022, coletadas nas bases de dados PUBMED, SciELO, LILACS e MEDLINE. Resultados: Em ratos normotensos, o LIN induziu hipotensão associada à taquicardia, enquanto em ratos hipertensos, reduziu a pressão arterial sem alterar a frequência cardíaca. O LIN tem ação direta sobre a vasculatura promovendo relaxamento vascular e melhora da função cardíaca. Interessantemente, a complexação de LIN com β-CDs melhorou a atividade anti-hipertensiva do monoterpeno. Conclusão: Foi evidenciado nesta revisão o potencial farmacológico do LIN como agente hipotensor, relaxante vascular e anti-hipertensivo. Além disso, há evidências que é possível melhorar o efeito anti-hipertensivo do LIN com a utilização de sistemas de inclusão com CDs, porém, estudos adicionais sobre este tema deverão ser realizados.
Nas trilhas da graphic novel
Authors: Vergueiro Waldomiro
Published: November 2023

Faz a resenha do livro Graphic novel: conceitos básicos, de Nobu Chinen.
Les vies du Prophète Muḥammad en Égypte ottomane
Authors: Soler Renaud
Published: November 2023

Cet article propose une réflexion sur l’écriture de la sīra, la « vie du Prophète », à partir de l’étude des catalogues de la Bibliothèque nationale égyptienne et de la Bibliothèque d’al-Azhar. L’analyse croisée des classifications des sciences médiévales et modernes, et des catégories utilisées par les catalogueurs à la fin du XIXe et dans la première moitié du XXe siècle, montre que la sīra était irréductible à la « biographie du Prophète », et recouvrait un ensemble de textes beaucoup plus large. La suite de l’article offre une description du corpus de 491 œuvres de sīra et des 1119 manuscrits et imprimés qui en sont les manifestations matérielles. Nous arrivons à la conclusion que ce corpus peut être utilisé pour décrire la culture de la sīra en Égypte et dans les provinces arabes de l’Empire ottoman. Deux résultats apparaissent particulièrement importants : la constitution de séries de textes (texte de base, commentaires, gloses) permet de décrire un pan majeur de la culture du commentaire à l’époque ottomane ; l’examen du corpus permet également d’offrir une perspective intéressante sur la transition entre la culture manuscrite et la culture imprimée dans l’Égypte du XIXe siècle.
No “Terror To Good Works, But To The Evil”
Authors: Marcoux J. Michel
Published: November 2023

Modern scholarship shows the enormity of Quaker religious sect misbehaviors starting about 1656 across colonial New England, including Quaker attacks on Plymouth Colony. After William Bradford’s 1657 death during that furor, Thomas Prence served as Plymouth governor for a third time. Prence made many valuable contributions to Plymouth and New England generally. However, unsurpassed among those achievements, his stout defense of Plymouth’s scripture based, separatist Puritan religious settlement against such Quaker attacks was especially meritorious. Scholarly insistence today on the vehemence of the threats posed to Plymouth by Quaker attackers, ca. 1656–62, validates continued appreciation of Prence’s disciplined responsive actions, emphatically voiced by Cotton Mather in the early 18th century.
Eternal Blue Sky 2.0
Authors: Chini Michelangelo
Published: November 2023

The revival of shamanism in Southern Siberia is increasingly characterised by online forms of representation. Through digital ethnographic research conducted in Russian, this paper argues that the internet reproduces non-digital narratives and practices endowing them with global, immediate reach in a very widely recognisable form, thus contributing to the amplification, legitimisation and contestation of shamanic power. Analysing the websites of two Irkutsk-area ‘shamanic centres’, I consider how digitalisation is contributing to the process of institutionalisation of shamanism, reproducing and further legitimising post-socialist hierarchies and structures of power in Buryat shamanism, while highlighting the malleable nature of shamanic power and the web alike. Conversely, I recur to the Buryat concept of khel am (a form of ‘omnipresent witchcraft’) in relation to two recent news stories of national relevance in Russia involving Siberian shamans, to illustrate the challenge posed by the over-amplification of shamanic power through digitalisation to shamans and their institutions’ claims to power.
Social and Economic Aspects of the Kuhmarim–Sehwalim Mazar in Khotan
Authors: Hällzon Patrick , Seher Tenha
Published: November 2023

Historical sources and recent data testify to the important role of the mazar pilgrimage in Uyghur daily life. The article deals with pilgrimage to Kuhmarim (alt. Köhmarim), a mazar ‘Muslim shrine’ close to Khotan, largely based on fieldwork by the authors who visited the shrine on separate occasions in 2009, 2015 and 2016. The shrine’s current status is unclear, but here we describe the pilgrimage as it was just before 2017. That was the year that the international community started receiving increasingly disturbing reports of the mass detention of Uyghurs, Kazakhs and other Muslim Turkic-speaking ethnic minorities in China. Given developments in the Uyghur homeland during the past few years, whereby hundreds or even thousands of mosques have been flattened to the ground together with the systematic destruction of numerous family tombs and holy shrines, this might be seen as a historical account of pilgrimage patterns, which still are not fully explored.
Peace in Northern Ireland: Navigating the Uncertainty of Brexit
Authors: Carlà Andrea , Grote Georg
Published: November 2023

With the ‘Troubles’, Northern Ireland has long reflected the problems of divided societies due to the presence of competing nationalisms. The deep divisions caused by the civil war and political stalemate could only be surmounted by the introduction of a European solution negating the binary and diametric opposition between Protestants and Catholics, unionists/ loyalists and nationalists/ republicans. Though many issues continued to affect Northern Ireland and its society, the 1998 Good Friday Agreement and its consociational power-sharing institutions managed to bring peace to the country within the EU framework. Recently, however, Brexit and the reestablishment of borders between the UK/ Northern Ireland and the EU (and thereby Ireland) are posing new challenges, reintroducing jingoistic and narrow- minded nationalist thinking. This article presents the development of the Northern Ireland issue, focusing on the impact of Brexit on the peace process in recent years and, in particular, exploring its effects from the perspective of identity and security.
Legal Standing of Individuals and ngo s in Environmental Matters under Article 9(3) of the Aarhus Convention
Authors: Passarini Federica
Published: November 2023

Individuals and non-governmental organizations’ access to justice in environmental matters may be hindered by a variety of obstacles, such as the fulfillment of legal standing conditions. In this regard, the Convention on Access to Information, Public Participation in Decision-making and Access to Justice in Environmental Matters (Aarhus Convention), on its Article 9(3), imposes on each State Party the obligation to ensure members of the public, “where they meet the criteria, if any, laid down in its national law”, to have access to justice in order to challenge any violation of national environmental law. In this contribution, I focus on this provision with the purpose of assessing its normative content regarding the criteria for legal standing. To this end, I analyze the interpretation of Article 9(3) given by the Aarhus Convention Compliance Committee (accc), as well as the relevant case law of domestic courts and the Court of Justice of the European Union (cjeu).
The Deterrent Effect of Financial Sanctions Pursuant to Article 260(2) tfeu in the Context of Violations of Environmental Obligations
Authors: Burelli Camilla
Published: November 2023

The paper aims at understanding whether financial sanctions pursuant to Article 260(2) tfeu have a deterrent effect in relation to specific types of State breaches, namely environmental ones. Spanning three parts, the paper examines how the different type of infringement affects the effectiveness of the payment of financial sanctions, and how these are not equally effective in relation to all types of breaches. Subsequently, it studies the features and issues of the Italian cases. On the bases on this empirical analysis, the article will try to answer the research question. Finally, proposals for amendments will be drawn up, assessing the feasibility of other forms of sanctions.
State Immunity from Civil Jurisdiction in Transboundary Environmental Litigations
Authors: Facchinetti Anna
Published: November 2023

The paper offers a de lege lata and de lege ferenda analysis of State immunity from civil jurisdiction in cases related to environmental transboundary damage, including climate change litigations. De lege lata, the analysis focuses on the customary exceptions to State immunity, namely the restrictive doctrine and the forum tort exception. De lege ferenda, the contribution firstly discusses the recent domestic case law lifting jurisdictional immunity for acts jure imperii which amount to serious violations of human rights and/or humanitarian law. Secondly, it seeks to open the discussion on a possible reform of the forum tort exception on the model of the European discipline of private international law in matters of tort, in order to ensure better protection of the individual right to an effective remedy.
Kuhlhasseltia motuoensis (Orchidaceae, Orchidoideae, Cranichideae), a new species from Xizang, China
Authors: YE CHAO , LI JIANWU , TIAN HUAIZHEN , LIN DONGLIANG , JIN XIAOHUA
Published: November 2023

N/A
A new species of Karschiola Gaede from Mozambique and Zimbabwe (Lepidoptera: Erebidae: Arctiinae) with updated information on the distribution of the genus
Authors: LÁSZLÓ GYULA M. , VOLYNKIN ANTON V.
Published: November 2023

The present paper provides the description of a new species of the genus Karschiola Gaede, 1926 from central Mozambique and Zimbabwe: K. ndzou sp. n. The pairwise genetic distance between the two Karschiola species is calculated and a neighbour-joining tree based on DNA barcodes of two K. holoclera and five K. ndzou sp. n. specimens is provided. The paper is illustrated with eight colour photos of adults and 18 genitalia images, a distribution map and two habitat photos.
Investigating the uptake and fate of per- and polyfluoroalkylated substances (PFAS) in bean plants (Phaseolus vulgaris): comparison between target MS and sum parameter analysis via HR-CS-GFMAS
Authors: Gehrenkemper Lennart , Rühl Isabel , Westphalen Tanja , Simon Fabian , von der Au Marcus , Cossmer Antje , Meermann Björn
Published: November 2023

In this study, we present a screening method based on molecular absorption spectrometry to study PFAS uptake and fate in plants. To evaluate the suitability of this method we analyzed plant extracts with molecular absorption spectrometry (MAS) as well as liquid chromatography–tandem mass spectrometry (LC–MS/MS) for mass balance studies (w(F)). French bean plants (Phaseolus vulgaris) were grown on soil spiked using eight PFAS substances that vary in chain length and functional group composition. Specifically, these include three short-chained (C4–C5), five long-chained (C7–C10) carboxylic acids, one sulfonic acid and one sulfonic amide moieties. To investigate substance-specific PFAS uptake systematically, PFAS were spiked as single substance spike. Additionally, we studied one mixture of the investigated substances in equal proportions regarding w(F) and four PFAS mixtures of unknown composition. After 6 weeks, the plants were separated into four compartments. We analyzed the four compartments as well as the soil for extractable organically bound fluorine (EOF) by high resolution-continuum source-graphite furnace-molecular absorption spectrometry (HR-CS-GFMAS) as well as for sum of ten target-PFAS by LC–MS/MS. All three short-chained PFAS perfluorobutanoic acid (PFBA), perfluorobutanoic sulfonic acid (PFBS) and perfluoropentanoic acid (PFPeA) were determined in high concentrations mainly in the fruits of the investigated plants while long-chained PFAS perfluorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA) were mainly determined in roots. PFBS was determined in remarkably high concentrations in leaves compartment by both quantification methods. Overall, comprehensive results of single substance spikes were in good agreement for both methods except for a few cases. Hence, two phenomena were identified: for mixed PFAS spikes of unknown composition huge differences between EOF and sum of target PFAS were observed with systematically higher EOF values. Overall, both methods indicate comparable results with MS being more reliable for known PFAS contamination and MAS being more valuable to identify PFAS exposure of unknown composition.

Graphical Abstract
Older adults’ experiences of participation in daily activities in Swedish assisted living
Authors: Jonasson Lise-Lotte , Bångsbo Angela , Billhult Annika , Wolmesjö Maria
Published: November 2023

Background

According to Swedish law, older adults in Sweden should be able to live a good, safe, and independent life with social and healthcare provided, based on their individual needs. In assisted living in Swedish eldercare the environment affects the older adults’ ability to participate in decision-making and strengthens their ability to feel meaningfulness. The ability of staff working in social and healthcare to invite older adults to participate varies. It is important to examine how older adults perceive their situation, as caregivers in eldercare tend to focus on routine work and experience difficulties in meeting the individual needs of older adults. The aim of this study was to explore how older adults in assisted living experienced participation in daily activities.

Methods

A qualitative interview study was conducted in two municipalities in the western part of Sweden. An exploratory and inductive design was used. Individual interviews were conducted with 11 older adults living in two different assisted living facilities. The data were analysed using thematic analysis.

Results

The interviews resulted in three themes: Being involved, Sense of well-being, and Influenced by the context. The older adults’ experiences of participation were interpreted as feelings of being involved in daily life activities, and how they felt involved in their own care and nursing. Participation created prerequisites for well-being. Sense of well-being could be related to feelings of security and social community. The organisation and work environment of the healthcare staff had a great impact on their ability to increase the participation of the older adults. The older adults were aware of the everyday work situation of the providers of social and healthcare and were Influenced by the context.

Discussion/conclusion

Important conditions for a good quality of life and participation for the older adults are to be treated with respect, receive information, and be able to choose. The older adults expressed several good ideas for improvements and a willingness to be involved in the development of the organisation at different levels. It is essential to invite older adults in assisted living to participate in the design of care and nursing.