bluuebunny/crossref_metadata_2025 huggingface dataset:
Health impact of the emissions from a refinery: case-control study on the adult population living in two municipalities in Lomellina, Italy
Authors: Gnesi Marco , Monti Maria Cristina , Ferraro Ottavia Eleonora , Borrelli Paola , Gigli Berzolari Francesca , Puci Mariangela Valentina , Oddone Enrico , Imbriani Marcello , Pelissero Gabriele , Cadum Ennio , Migliazza Simona , Montomoli Cristina , Villani Simona
Published: April 2023

Background: In the municipalities of Sannazzaro de’ Burgondi and Ferrer Erbognone (District of Lomellina, Pavia, Lombardy, Italy), an oil refinery is operating since 1963. In 2008, the company running the plant (eni S.p.A.) asked the competent bodies the permission for building a new facility (“EST”). The present work is aimed at evaluating the ante-operam health impacts of the existing facility refinery.
Methods: A case-control study design was implemented. Cases were subjects admitted to hospital in 2002-2014 due to acute respiratory, cardiovascular or gastrointestinal conditions. Controls were selected among those who had not been hospitalised in that timespan. Cases and controls had to be alive at enrolment, aged 20-64 years, and were frequency-matched by age, gender and municipality. Data were extracted from the health insurance registry and from Hospital Discharge Records (ATS Pavia). Enrolled subjects were asked to complete a mailed survey. Environmental exposure was the fallout of refinery emissions (PM10) at participants’ homes, as predicted by an AERMOD model.
Results: 541 respondents (125 cases, 416 controls) were included in the analyses. Response bias was excluded. Individual PM10 exposure was not significantly different between cases and controls, while it was significantly associated with municipality (being higher in Sannazzaro). The crude effect estimate of PM10 over case/control status indicated a not-significant excess of hospitalisation with the increase in PM10 exposure. Multivariate analyses confirmed those results.
Conclusion: Findings indicate a possible excess of hospitalisation risk in most exposed people, but the effect is not statistically significant and may be affected by bias.
Obstetric and perinatal outcomes of teenage pregnant women: a retrospective study
Authors: Derme Martina , Leoncini Emanuele , Vetrano Giuseppe , Carlomagno Lisa , Aleandri Vincenzo
Published: April 2023

Background: teenage pregnancy is a worldwide social problem. The aim of this study is to provide more data for a better understanding of the possible maternal and foetal risks associated with teenage pregnancies.

Methods: the hospital records of all pregnant women, aged between 14 and 19, from the obstetric registers of the Policlinico Umberto I Hospital in Rome, between 2000 and 2010, have been completely reviewed (n=184). For each pregnant woman socio-demographic characteristics, obstetric history, pregnancy and birth outcomes were also determined. Our results were compared with a control group composed of 150 primigravida adult women aged 20-29 years who delivered at the Policlinico Umberto I Hospital in Rome in the same period.

Results: the mean age ± SD of the study group was 17.9 ± 1.2, while that of the control group was 25.4 ± 2.4. The control group had a significantly lower risk of preterm delivery (p=0.000). The rate of low birth weight babies born to the young mothers was significantly higher than that of babies born to the adult mothers (p=0.036). The study group had a lower risk of instrumental delivery and a higher proportion of spontaneous delivery (p=0.000). Finally, we observed a statistically significant difference of the APGAR score at the fifth minute between the two groups (p=0.004).

Conclusions: our results seemed to confirm the outcomes of previous studies for adolescent pregnant women, mainly regarding the increased risks of preterm deliveries and low birth weight babies, the higher incidence of spontaneous vaginal delivery and the lower incidence of instrumental delivery.
Comparison of multi-state Markov models for cancer progression with different procedures for parameters estimation. An application to breast cancer
Authors: Ventura Leonardo , Carreras Giulia , Puliti Donatella , Paci Eugenio , Zappa Marco , Miccinesi Guido
Published: April 2023

Background: the knowledge of sojourn time (the duration of the preclinical screen-detectable period) and screening test sensitivity is crucial for understanding the disease progression and the effectiveness of screening programmes. For this purpose a model of the natural history of the disease is needed. The aim of this work is to provide an illustration of the application of multistate Markov models for breast cancer progression to the data of the Florentine screening programme, in order to estimate the sojourn time and sensitivity for breast cancer screening.

Methods: three different multi-state Markov models of increasing complexity were used with three different estimation procedures based on non-linear least squares, maximum likelihood, and on a Bayesian approach. All the models produced estimates for screening sensitivity and mean sojourn time. The data used in our application seem to lead to a non-identifiability problem, since the estimation procedures for both the Maximum Likelihood and Non-Linear Least Squares gave estimates that changed with the parameters’ initial values or difficultly converged. In order to take this problem into account we used the Bayesian Approach by incorporating prior information on all the parameters.

Results: the mean sojourn time varied between 2-7 years and 3-5 years for women aged 50-59 and 60-69, respectively. When the model complexity was increased a higher variability in estimates was observed among the estimation procedures. The results of the screening sensitivity estimates were highly variable, both among estimation techniques and models - varying between 63% and 100%, and between 77% and 100% for women aged 50-59 and 60-69, respectively.

Conclusions: results are in accord with the literature; those obtained through the Bayesian Approach seem to be more reliable.
Knowledge, attitudes and practices towards patients with HIV/AIDS in staff nurses in one university hospital in Sicily
Authors: Marranzano Marina , Ragusa Rosalia , Platania Marco , Faro Giuseppina , Coniglio Maria Anna
Published: April 2023

Background: nurses’ knowledge, attitudes and practices towards patients with HIV/AIDS are of ongoing interest, especially in developing countries. Nothing or very little is known about Italian nurses.

Methods: HIV/AIDS knowledge, attitudes and behaviours of the nurses (n=107) from one university hospital inCatania,Sicily, were documented. Comparisons among nurses belonging to different Operative Units (O.U.) were conducted by the chi-square test (P<0.05).

Results: although HIV was nurses’ main concern in regard to contracting infections in the workplace (54%), the vast majority of them (98%) had never refused an HIV/AIDS patient care assignment. Moreover, despite their concern of being more at risk of contracting HIV than the general population (41%), a not negligible percentage of nurses did not use gloves routinely (21%) and only a few treated all patients as potentially HIV-positive (9%). The vast majority of the respondents knew the meaning of AIDS (87%) and of a positive serological test (78%). On the contrary, a relatively low percentage of them knew what is the ‘window period’ (62%) and were acquainted with HIV pathophysiology (65%). No statistically significant differences in terms of risk perception were found between nurses who had previously attended an HIV/AIDS workshop, lecture or specific course (43%) and nurses who did not (57%). Level of knowledge was positively associated to age (P=0.000) and to education (P=0.016), and it was found higher in nurses working in a O.U. of Infectious Diseases.

Conclusions: data from our study show that also in developed countries, such as Italy, nurses could have some misconceptions and concerns about HIV/AIDS. The importance of examining the impact of continuing education on nurses’ preparedness to care for patients with HIV/AIDS and to prevent the risks of occupational HIV transmission is discussed.
The use of fractal dimension methods in clinical epidemiology: an application for postural assessment
Authors: Masedu Francesco , Angelozzi Massimo , Di Giminiani Riccardo , Valenti Marco
Published: April 2023

Background: this study considers the analysis of postural sway by comparing the use of a fractal dimension outcome (DBOX) with the usual sway ellipse area (SEA), calculated by the least squares method. Both the response variables come from centre of pressure (COP) dynamics detected by means of a force platform.

Methods: recent literature regarding postural stability assessment in subjects with muscularskeletal disorders, or neuromuscular diseases affecting their motor skills, has suggested, both for practical and theoretical reasons, the use of some fractal dimension as a good outcome measurement for overall postural status. A sample group of 24 male subjects was recruited. The postural stabilogram was recorded both with eyes open (EO) and eyes closed (EC) while standing upright. A matched-pair comparison of the sway ellipse area with the COP dynamics box counting dimension was performed. A ROC analysis of the outcome variables was performed. Then, a ROC comparison of the tests, using the area under the curve (AUC) index, was conducted.

Results: the comparison of paired groups showed a statistically significant difference between EO and EC status, according to the sway ellipse area and the fractal dimension (p<0.05). The ROC analysis, describing the test performance in terms of AUC difference, was statistically significant (p<0.05). The comparison of the AUCs showed an overall superior performance of the DBOX with respect to SEA (p<0.05).

Conclusions: this study showed a statistically significant better overall performance of DBOX with respect to SEA, suggesting possible improvements of clinical practice, as well as theoretical insights into the response patterns.
Some uses of predictive probability of success in clinical drug development
Authors: Gasparini Mauro , Di Scala Lilla , Bretz Frank , Racin-Poon Amy
Published: April 2023

Predictive probability of success is a (subjective) Bayesian evaluation of the prob- ability of a future successful event in a given state of information. In the context of pharmaceutical clinical drug development, successful events relate to the accrual of positive evidence on the therapy which is being developed, like demonstration of su- perior efficacy or ascertainment of safety. Positive evidence will usually be obtained via standard frequentist tools, according to the regulations imposed in the world of pharmaceutical development.Within a single trial, predictive probability of success can be identified with expected power, i.e. the evaluation of the success probability of the trial. Success means, for example, obtaining a significant result of a standard superiority test.Across trials, predictive probability of success can be the probability of a successful completion of an entire part of clinical development, for example a successful phase III development in the presence of phase II data.Calculations of predictive probability of success in the presence of normal data with known variance will be illustrated, both for within-trial and across-trial predictions.
A retrospective analysis of 3 156 admissions with fever of unknown origin in a large Italian hospital
Authors: Nicolotti Nicola , Cattel Caterina , Gualano Maria Rosaria , Soriano Alessandra , Manna Raffaele , Boccia Stefania
Published: April 2023

Background: fever of unknown origin (FUO) is defined as a fever with no etiologic diagnosis after standardized investigations performed during 3 days in hospital or after at least 3 ambulatory visits. Our study aims to describe the epidemiology of classic FUO through the retrospective analysis of 902 861 admissions to a large University Hospital in Italy, to investigate its temporal trend, and to evaluate differences between young and old patients.

Methods: we retrieved data records of all the admissions between the 1st January 1988 and 31st December 2007. Proportional admission rate (PAR ) of FUO was calculated. Time trends of FUO admissions were analysed by joinpoint regression, with time changes expressed as Expected Annual Percent Change (EA PC). The ICD 9-CM code was used to identify the diagnosis on discharge of FUO cases.

Results: in the study period 3 156 patients were admitted with a diagnosis of FUO (PAR=3.50 per 1 000). The time-trend analysis showed two joinpoints, the first in 1995 (EAPC of 307.80, 95% CI: 89.66-776.84, p=0.002), and the second in 1998 (EAPC=-8.57, 95% CI: -10.37-6.73; p<0.001). Around 22% of admissions remained without a definitive diagnosis of FUO, with this percentage being lower in patients ≥65 years compared with subjects aged 21-64.

Conclusions: FUO is a leading cause of admission to hospitals, as well as of morbidity and mortality, thus representing a challenge for diagnostic medicine and hospital care. It is necessary to develop a diagnostic methodology for FUO , so as to reduce costs of preventable hospitalizations.
Epidemiology, Biostatistics and Public Health, EBPH: a new vision for two old journals
Authors: Boccia Stefania , La Vecchia Carlo
Published: April 2023

The launch of this new journal, Epidemiology, Biostatistics and Public Health (EBPH), enables us to embrace new challenges, and renew our commitment to our readers, our authors and fellow editors, and ultimately to the public health community worldwide.

EBPH is an open access journal streaming from two previous journals, one focused on public health (The Italian Journal of Public Health, http://ijphjournal.it/) [1-8], ...
Magnitude of the smoking problem, knowledge, attitude and practice, among family members of primary school students
Authors: Nakhostin-Roohi Babak , Sojudi Aghdas , Hosseini Mahdi Khorshidi
Published: April 2023

Background: smoking is a very important public health problem, urgently requiring immediate and effective measures due to its harmful effect on health. The purpose of this study was to collect baseline information about the magnitude of smoking problem, knowledge, attitude, and practice among family members of primary school students in the northwest region of Iran.

Methods: of 55 680 primary school students (the 3th, 4th and 5th grades), 7.1% (n=3 954) were selected using randomized multi-stage cluster sampling. Data collection was conducted in April, May, and June 2011, by means of a self-administered two-page questionnaire.

Results: a total of 3 954 students (57.6% boys and 42.3% girls) with the mean age of 10.46±1.09 years were evaluated. According to our data, the prevalence of cigarette smoking among fathers was more than other family members (27.1% versus 17.8%) whereas the prevalence of water pipe smoking among fathers and other family members was almost similar (9.2% and 9.7% respectively). None of the smoking type was prevalent among mothers (cigarette: 1% and water pipe: 1.1%). Considerable numbers of all students under study had been exposed to secondhand smoke at home (cigarette: 19.8% and water pipe: 7.7%).

Conclusions: considering our findings, two procedures recommended to prevail the problem are to provide greater education about hazards of tobacco consumption among students and their family; and to legislate new laws by officials to ban tobacco use at home.
Administrative databases as a tool for identifying healthcare demand and costs in an over-one million population
Authors: Madotto Fabiana , Riva Michele A. , Fornari Carla , Scalone Luciana , Ciampichini Roberta , Bonazzi Chiara , Mantovani Lorenzo G. , Cesana Giancarlo
Published: April 2023

Background: the aim of this study was to assess healthcare demand of specific groups of population and their costs borne by Italian Health System, using healthcare administrative databases.

Methods: demographic, clinical and economic data were obtained from datasets available at the Regional Health System, combined into a data warehouse (DENALI), using a probabilistic record linkage to optimize the data matching process. The study population consisted of more than 1 million people registered in 2005 at one Local Healthcare Unit of Lombardy. Eight different segments were identified. Costs occurring in 2005 for hospital admissions, drug prescriptions, outpatient medical specialist visits were quantified in each segment.

Results: healthy people accounted for 53% of the population and cost € 180 per-capita. Subjects with only one chronic disease made up 16% of the population and cost € 916 per-capita, those affected by several chronic diseases accounted for 13% and cost € 3 457 per-capita. Hospitalizations were the cost driver in five segments, ranging from 42% to 89% of total expenditures. Outpatient visits were the cost driver among healthy subjects (54%) and those with a possible chronic disease (42%), while drug costs ranged between 4% (“acute event”) and 32% (“one chronic disease”). Overall, healthcare cost was € 809 per-capita.

Conclusions: healthcare costs were mainly determined by people affected by chronic conditions, even if “healthy people” ranked third for total expenditure. These costs need an appropriate identification of healthcare demand, that could be efficiently monitored through the use of administrative databases.
Prevalence and effect of schistosome and soil-transmitted helminth infection on labour input in rice-growing communities of Ogun State, Nigeria
Authors: Sam-Wobo Sammy Olufemi , Akintola Olushola , Atungwu Jonathan , Ekpo Uwem Friday , Adeleke Monsuru Alani , Mafiana Chiedu Felix
Published: April 2023

Schistosomiasis and soil-transmitted helminthiasis (STH) are public health problems in communities which lack basic social amenities with poor hygienic conditions. Studies were carried out to determine the prevalence and effect of schistosomes and soil-transmitted helminths infection on labour input on rice production in 9 rice-growing communities of Ogun State. Parasitological examinations of urine and faecal samples, and structured questionnaires were conducted on 243 consented individuals from May 2009 to March 2010. The results showed an overall prevalence of 17% for Ascaris lumbricoides, 12% for hookworms, 2% for Trichuris trichiura, 1% for Schistosoma haematobium and 1% for Schistosoma mansoni. A. lumbricoides and hookworms were more prevalent in Agbajege (25%), and varied in the other 8 communities. T. trichiura was prevalent in three communities, Agbajege (5%), Akodu (4.2%), and Moloko-Asipa (4.8 %); S. haematobium was prevalent only in Ayedere (2.6%) and Lufoko (8%), while S. mansoni was prevalent only in Moloko-Asipa (9.5%). Infections among the gender were varied as 26.3 % of males and 33.8 % of females had an overall prevalence of: A. lumbricoides (16.8%), hookworms (11.8%), T. trichiura (1.6%), S. haematobium (1.1%) and S. mansoni (1.1%). On frequency of infection to incapacitation per year, 45% of respondents were incapacitated 1-2 times, 27% 3-4 times and 19% were incapacitated more than 4 times. Understanding the effect of these two diseases will not only improve the health status of residents but also increase their productivity and ensure food security.
Environmental lithium exposure in the north of Chile - Tissue exposure indices
Authors: Figueroa Leonardo T. , Barton Sara Ann , Schull William J. , Young Allan H. , Kamiya Yumi M. , Hoskins John A. , Ilgren Edward B.
Published: April 2023

Background: northern Chile has the highest levels of lithium in surface waters in the world which is reflected in very high lithium levels in the plants and animals that depend on these water systems and consequently in the indigenous population.

Methods: the lithium tissue burdens in populations from two valleys in the extreme north of Chile have been studied. The bulk of this report is based on analyses of lithium levels in urine, hair, and breast milk in the population of several villages. Data on serum levels, some of which had been previously published, are included for the sake of completeness. Since this paper reports studies by several groups of workers samples were analysed by a variety of methods. These include atomic emission, atomic absorption, other photospectroscopic techniques and mass spectroscopy.

Results: in all samples studied the average lithium level (5.3 ppm) was found to be significantly elevated compared to levels reported in the literature and measured in this study for people not exposed to high levels in water and food (0.009-0.228 ppm).

Conclusions: the people studied represent a unique longitudinal cohort. The work should provide important insights into the potential neuroprotective effects of lithium also help us set guidelines to assess the risks from high dose environmental exposure.
An investigation on prevalence of Anemia in relation to BMI and nutrient intake among adult rural population of West Bengal, India
Authors: Pal Amitava , De Sujaya , Sengupta Piyali , Maity Payel , Dhara Prakash C.
Published: April 2023

Background: Anemia is now globally recognized major public health problem. The present study was undertaken to investigate the prevalence of anemia and interrelationship of anemia with BMI among adult rural population of West Bengal state, India.

Method: Anthropometric measures, nutritional parameters, heart rate and hemoglobin were measured from 310 adult subjects by using standard technique.

Results: The prevalence of anemia was high among both sexes and more than the global prevalence. The anemic individuals consumed nutritionally deficient diet than the non-anemic individuals. The prevalence of anemia was significantly high in underweight and normal groups. The Odds ratios became significantly higher in underweight group than normal and overweight/obese groups of both sexes.

Conclusions: The prevalence of anemia in the adult rural population might be related to dietary deficiency and poor dietary patterns. The present study was hypothesized that the subjects with low BMI would have a higher risk of anemia compared to normal or overweight subjects.
Environmental risk factors in the aetiology of multiple sclerosis in Kayseri: a case control study
Authors: Günal Servin Yeşil , Mirza Meral
Published: April 2023

Background: our purpose is to evaluate the possible relationship between multiple sclerosis (MS) and environmental factors in Kayseri.

Methods: this case control study was conducted on 100 patients with MS and 100 sex-aged and residential area matched control. Data was collected by using face to face interviews. Questionnaire consisted of two parts. The first part was comprised of items related with the participants’ sociodemographic features. The second part was related with factors thought to be involved in the occurrence or aggravation of the disease. The Chi-square test and logistic regression were used for analysis.

Results: logistic regression analysis revealed the following as possible risk factors in MS cases: economic status (Odds Ratio (OR): 0.14 adjusted 7.19; Confidence Interval 95% (CI): 0.05-0.43), having a sensitive personality (OR:4.51; 95% CI: 1.10-18.45), familial history of MS (OR:3.28; 95% CI: 1.3-8.27), history of cranial and spinal injury (OR: 2.99; 95% CI: 1.11-8.08), cooking oil consumption (OR:0.07 adjusted 13.5; 95% CI: 0.03-0.20), consumption of legumes and grains (OR: 0.11 adjusted 8.9; 95% CI: 0.03-0.41), and living in dwellings within a distance of 500 meters from transformer basestations (OR: 6.5; 95% CI: 1.54-28.21).

Conclusions: we believe that it is necessary to inform the individuals about the risk of MS and their relatives of the results of large-scale joint studies and to offer suggestions based on the data obtained.
Detecting outliers and/or leverage points: a robust two-stage procedure with bootstrap cut-off points
Authors: Marubini Ettore , Orenti Annalisa
Published: April 2023

This paper presents a robust two-stage procedure for identification of outlying observations in regression analysis. The exploratory stage identifies leverage points and vertical outliers through a robust distance estimator based on Minimum Covariance Determinant (MCD). After deletion of these points, the confirmatory stage carries out an Ordinary Least Squares (OLS) analysis on the remaining subset of data and investigates the effect of adding back in the previously deleted observations. Cut-off points pertinent to different diagnostics are generated by bootstrapping and the cases are definitely labelled as good-leverage, bad-leverage, vertical outliers and typical cases. The procedure is applied to four examples.
Assessment of seasonal influenza vaccine effectiveness in patients from a central Italy reference hospital: pitfalls and intricacies from a pilot case-control study
Authors: De Gaetano Donati Katleen , Costanzo Simona , Campana Lara , Olivieri Marco , Santangelo Rosaria , Sanguinetti Maurizio , Cauda Roberto , Iacoviello Licia
Published: April 2023

Objectives: Influenza vaccination protects high-risk populations from severe outcomes. We assessed the feasibility of testing influenza vaccine effectiveness against hospitalization with laboratory-confirmed influenza.

Methods: All hospitalized patients with influenza-like illness within 14 days, were swabbed. Cases were positive at RT-PCR for influenza A/B.

Results: AtRome “GemelliHospital” (Season 2011-2012) 104 patients were contacted and 62 recruited. Considering total sample and target group (n= 47, 76%), only 29% and 38% had been vaccinated. Eighteen patients were laboratory-conﬁrmed for influenza.

Conclusions: RecruitedILI patients and prevalence of vaccinated subjects were less than expected. Larger numbers are warranted to study vaccine effectiveness against severe influenza outcomes.
Association of Risk Perception and Information Provided on the Labels of Over-the-Counter Drugs: Role of Race, Education, Age and Income
Authors: Singh Neha , Suda Katie J. , Mathur Sunil
Published: April 2023

Background: The use of over-the-counter (OTC) drugs has increased tremendously, however, information on risk perception regarding the use of OTC drugs and their potential toxicity is scarce. Hence, the purpose of this study was to investigate the perception of OTC drug safety and efficacy based on reading product packaging and the effect of race, education, age and income. Methods: We used the HINTS 2012 data set with total sample size of 2,554. 

Results: OTC drug users having some high school education had a lower chance of frequently reading information included in the product labeling with the OTC medication. OTC drug users less than 50 years of age were always likely to read drug information on the OTC drug labeling. Also, Non-Hispanic blacks were more likely to read OTC drug labeling than Non-Hispanic whites.  OTC drug users less than 50 years of age consider OTC drugs safer than prescription drugs.  Conversely, OTC drug users with a high school, some college or bachelor’s degree consider OTC drugs less safe than prescription drugs.  Non-Hispanic blacks, non-Hispanic whites, and subjects of lower income were less likely to consider OTC drugs safer than prescription drugs.  OTC drug users with a high school education and some college perceive OTC drugs to be less effective than prescription drugs.

Conclusion: To conclude, age, education, race, and income affect risk perception on OTC drugs.  Consumer information programs need to be designed so that meaningful results can be incorporated into public policy. Providing information on the labeling of OTC drugs and likelihood of patients reading this information require further study.
A population-based survey on sociodemographic risk factors of cigarette smoking among Iranian women of reproductive age
Authors: Baheiraei Azam , Mirghafourvand Mojgan , Charandabi Sakineh Mohammad-Alizadeh , Nedjat Saharnaz , Mohammadi Easa
Published: April 2023

The trend of smoking among women is rising in some developing countries. The objective of this population-based cross-sectional study was to determine the sociodemographic risk factors of cigarette smoking among Iranian women of reproductive age. A total of 1359 women were randomly selected for the study. Multivariable logistic regression analysis was used to estimate the adjusted association between sociodemographic variables and cigarette smoking. The odds of cigarette smoking were higher among divorced women (OR [odds ratio]: 14.0; 95% CI [confidence interval]: 4.1–47.3) and women with a university education (OR: 2.6; 95% CI: 1.3–5.0). This study highlights an association between marital status and education with cigarette smoking among Iranian women.
Outdoor air pollution and lung cancer: what now?
Authors: Pira Enrico , Piolatto Pier Giorgio
Published: April 2023

In the last decade a substantial number of epidemiological studies suggested that outdoor air pollution and in particular respirable particulate matter (PM10) and fine particulate matter (PM2.5) are associated with an increased risk of lung cancer.The most recent is a multicentre European study...
Joint Modeling of Multivariate Longitudinal Depressive Symptoms and Survival with Application to an Aging Study
Authors: Yao Ping , Liu Xiaohong
Published: April 2023

Objective The primary aim in this study was to use a joint analysis approach to examine the association between longitudinal depressive symptoms and survival in Mexican Americans.

Methods:  The separate Cox regression and joint modeling were applied to data from the Hispanic Established Population for Epidemiological Study of the Elderly (HEPESE). Depressive symptoms were measured by the Center of Epidemiological Studies Depression Scale (CES-D). The trajectories of CES-D, modeled by random effect, were used as independent variables to fit the mortality curve adjusted by other variables including demographics and physical functioning.

Results: The separate Cox regression couldn’t identify association between depressive symptoms and survival. The joint analysis indicated that the  slope of  CES-D score was not associated with mortality in older Mexican-Americans, however the intercept had negative effects on mortality.

Conclusion: There was significant association between baseline depression symptoms and mortality, while no association with slope in older Mexican Americans
Out-of-home eating frequency, causal attribution of obesity and support to healthy eating policies from a cross-European survey
Authors: D'Addezio Laura , Turrini Aida , Capacci Sara , Saba Anna
Published: April 2023

Background: The relation between the increased out-of-home food consumption and the rising of overweight and obesity prevalence rates has been widely assessed, and the a key role played by the catering sector in ensuring healthy food choices has been recognised. Governments’ healthy eating policies have a wide range of action, influencing consumer behavior, and the socioeconomic and  food environments, with specific actions for the catering sector. Information on the public support for these policies could help policy makers in planning decisions. This study aims to investigate the relationship of out-of-home eating frequency with beliefs about obesity causes, support to healthy eating policies, and with socio-demographic factors.

Methods: Data on 3003 individuals from Belgium, Denmark, Italy, Poland and United Kingdom, of both sexes, aged ≥16 years, were employed, from the European survey on policy preferences (Eatwell). Data were analysed through Chi-square test and logistic regression analysis.

Results: Out-of-home eating varied with gender, age, marital status, education, BMI, and by country. Convenience food consumption was positively associated with obesity attribution to genetics, and inversely associated with attribution to lack of willpower. Attributions of obesity to lack of time, and to lack of self-control were associated with increased likelihood to consume fast-food and ready-prepared food respectively. Out-of-home eating people expressed higher support for information-based prevention, and actions aimed at healthier out-of-home eating, and lower support for restrictions and regulations of the food supply environment.

Conclusion: Future research on out-of-home food consumers and their support towards public interventions for the catering sector, could have important implications for effective strategies to promote healthy eating.
On the thermal safety of battery materials for electric vehicles
Authors: Alfaruqi Muhammad Hilmy
Published: April 2023

N/A
Primary and secondary paediatric hypertension
Authors: Bassareo Pier Paolo , Calcaterra Giuseppe , Sabatino Jolanda , Oreto Lilia , Ciliberti Paolo , Perrone Marco , Martino Francesco , D’Alto Michele , Chessa Massimo , DI Salvo Giovanni , Guccione Paolo
Published: April 2023

High blood pressure (BP) or hypertension is a well known risk factor for developing heart attack, stroke, atrial fibrillation and renal failure. Although in the past hypertension was supposed to develop at middle age, it is now widely recognized that it begins early during childhood. As such, approximately 5–10% of children and adolescents are hypertensive. Unlike that previously reported, it is now widely accepted that primary hypertension is the most diffuse form of high BP encountered even in paediatric age, while secondary hypertension accounts just for a minority of the cases. There are significant differences between that outlined by the European Society of Hypertension (ESH), the European Society of Cardiology (ESC), and the last statement by the American Academy of Pediatrics (AAP) concerning the BP cut-offs to identify young hypertensive individuals. Not only that, but the AAP have also excluded obese children in the new normative data. This is undoubtedly a matter of concern. Conversely, both the AAP and ESH/ESC agree that medical therapy should be reserved just for nonresponders to measures like weight loss/salt intake reduction/increase in aerobic exercise. Secondary hypertension often occurs in aortic coarctation or chronic renal disease patients. The former can develop hypertension despite early effective repair. This is associated with significant morbidity and is arguably the most important adverse outcome in about 30% of these subjects. Also, syndromic patients, for example those with Williams syndrome, may suffer from a generalized aortopathy, which triggers increased arterial stiffness and hypertension. This review summarizes the state-of-the-art situation regarding primary and secondary paediatric hypertension.
POHON URBAN BLORA: RUANG REHAT UNTUK KOMUTER DI JALAN BLORA
Authors: Lumanauw Juan Valentino , Sutanto Agustinus
Published: April 2023

Blora Street is a road in the Menteng area, Central Jakarta. This street is famous for its shops which are lined up along Jalan Sudirman. However, due to a change in the configuration of the Jalan Blora area, the movements that occur are also changing, and this causes the area to no longer be as busy as it used to be. For this reason, an architectural approach by means of urban acupuncture is used to try to revive an area that is increasingly losing its hustle and bustle. This project is located on one of the vacant lands in the Blora street shopping strip. This project proposes the construction of a break room to meet the community's need for open space as well as a transit space for the community to take a short break from work and the commuting lifestyle they always do. This project aims to provide a space for people to "breathe" in the middle of Jakarta with a lifestyle that is driven by time. The project was designed using the third place method to consider the mobility and possibilities of the new attractor and its relation to the upcoming TOD master plan project in the area. With the results of the project being a form of solution to provide a new attractor for human movement in the area.
Keywords:  commuter; Blora street; stopover; rest
Abstrak
Jalan Blora merupakan jalan yang berada di Kawasan Menteng, Jakarta Pusat. Jalanan ini terkenal dengan pertokoannya yang berjejer di sepanjang Jalan Sudirman. Namun karena adanya perubahan konfigurasi Kawasan Jalan Blora, maka pergerakan yang terjadi pun kian berubah, dan mengakibatkan Kawasan tersebut tidak lagi ramai layaknya waktu dahulu. Untuk itu pendekatan arsitektur dengan cara akupuntur urban digunakan untuk mencoba menghidupkan Kembali Kawasan yang semakin lama semakin hilang keramaiannya. Proyek ini berlokasi di salah satu lahan kosong yang ada di strip pertokoan jalan Blora. Proyek ini mengusulkan pembangunan ruang rehat untuk memenuhi kebutuhan masyarakat akan ruang terbuka serta ruang singgah bagi masyarakat untuk istirahat sejenak dari pekerjaan serta gaya hidup komuter yang selalu mereka lakukan. Proyek ini bertujuan untuk memberikan sebuah ruang bagi masyarakat untuk “bernafas” di tengah kota Jakarta dengan gaya hidup yang terpacu oleh waktu. Proyek di desain menggunakan metode tempat ketiga untuk mempertimbangkan pergerakan dan kemungkinan atraktor yang baru serta keterkaitannya dengan proyek masterplan TOD yang akan datang di daerah tersebut. Dengan hasil proyek menjadi salah satu bentuk solusi untuk memberikan atraktor baru bagi pergerakan manusia di daerah tersebut.
RUANG EKONOMI BERBASIS AGRIKULTUR DAN PENGOLAHAN AIR KOTOR DENGAN MENGGUNAKAN INSTALASI PENGOLAHAN AIR ALAMI PADA KAMPUNG APUNG
Authors: Herijanto Dewi Nathania , Liauw Franky
Published: April 2023

Located in rice fields, Kampung Apung was the same as other villages in that it was on the ground and not floating. However, due to changes in topography, time and urban needs, there has been considerable development into an industrial and warehousing area in the surroundings of the Apung village so that the village becomes hollow and sinks. Changes in the area into industry and warehousing have resulted in the area experiencing a shortage of infiltration areas. The sinking of the village interrupts the daily activities of the residents, disrupts the economy and social life of the residents. Local interventions are presented through Urban Acupuncture using everyday methods and typology. The choice of this method is expected to cure the issue of degradation that occurs in the Kampung Apung. The program presented is in the form of structuring Floating Villages into vertical villages and making creative economic activities in villages with an agricultural base that is equipped with dirty water treatment. It is hoped that the presence of this additional program can increase the economy of the residents of the Kampung Apung so that it can have a positive impact on the Apung village.
Keywords:  Economic space; agriculture; natural water treatment plant
Abstrak
Berada pada lahan persawahan di Kapuk, Jakarta Barat, Kampung Apung awalnya sama seperti kampung lainnya yang berada di atas tanah dan tidak terapung. Tetapi karena perubahan topografi, zaman dan, kebutuhan kota, terjadi pembangunan yang cukup besar menjadi kawasan industri dan pergudangan pada lingkungan sekitar kampung Apung sehingga kampung menjadi cekungan dan tenggelam. Perubahan fungsi kawasan menjadi perindustrian dan pergudangan mengakibatkan kawasan mengalami kekurangan area resapan. Tenggelamnya kampung mengganggu aktivitas keseharian warga, perekonomian, dan sosial warga. Intervensi lokal dihadirkan melalui Urban Acupuncture dengan menggunakan metode keseharian dan tipologi. Pemilihan metode ini diharapkan dapat menyembuhkan isu degradasi yang terjadi pada kampung Apung. Program yang dihadirkan berupa penataan Kampung Apung menjadi kampung vertikal dan pembuatan kegiatan ekonomi kreatif pada kampung dengan basis agrikultur yang dilengkapi dengan pengolahan air kotor. Diharapkan dengan hadirnya program tambahan ini dapat menaikkan perekonomian warga kampung Apung sehingga dapat memberi dampak positif bagi kampung Apung.
STUDI POTENSI DESTINASI WISATA DESA SAPORKREN KABUPATEN RAJA AMPAT
Authors: Komiter Lod Gamaliel , Rahardjo Parino
Published: April 2023

Saporkren Village has natural and cultural potential as a tourist destination. To be more attractive to tourist visits, a more planned village potential development concept is needed and in accordance with recommendations for the progress of the Saporkren Tourism Village. The potential of a tourism village is the potential for a village-based tourist destination where there are various factors that support the progress of a tourist village. The potential includes policies, location, site, landscape/culture, accommodation/facilities, services and prices. As well as the feasibility factors of tourist villages such as Cultural and Natural Resources, Promotion and Preservation of Cultural Resources, Economic Sustainability, Social Sustainability, Environmental Sustainability, Tourism Potential and Development and Value Chain Integration, Tourism Governance and Priority, Infrastructure and Connectivity, Health, Safety and Security. The purpose of this study was to determine the natural and cultural potential, as well as the physical condition of the Saporkren Tourist Village and also to determine the condition of the buildings and infrastructure of the Saporkren Tourist Village. This potential study will produce conclusions and recommendations that can be used for the development of the Saporkren Tourism Village.
Keywords: potential; Saporkren; tourism; tourist destinations; tourist village
Abstrak
Desa Saporkren memiliki potensi alam dan budaya sebagai destinasi wisata. Untuk lebih menarik kunjungan wisata diperlukan konsep pengembangan potensi desa yang lebih terencana dan sesuai dengan rekomendasi demi kemajuan Desa Wisata Saporkren. Potensi Desa wisata adalah potensi destinasi wisata berbasis desa dimana ada berbagai faktor yang mendukung dalam kemajuan suatu desa wisata. Adapun potensi tersebut seperti kebijakan, lokasi, tapak, lansekap/culture, akomodasi/fasilitas, pelayanan dan harga. Serta faktor-faktor kelayakan desa wisata seperti Sumber Daya Budaya dan Alam, Promosi dan Pelestarian Sumber Daya Budaya, Keberlanjutan Ekonomi, Keberlanjutan Sosial, Kelestarian Lingkungan, Potensi dan Pengembangan Pariwisata dan Integrasi Rantai Nilai, Tata Kelola dan Prioritas Pariwisata, Infrastruktur dan Konektivitas, Kesehatan, Keselamatan dan Keamanan. Tujuan penelitian ini untuk mengetahui potensi alam dan budaya, serta kondisi fisik Desa Wisata Saporkren dan juga untuk mengetahui kondisi bangunan dan infrastuktur Desa Wisata Saporkren. Studi potensi ini akan menghasilkan kesimpulan dan rekomendasi yang bisa digunakan untuk pengembangan Desa Wisata Saporkren.
ASPECTOS DA ABORDAGEM TERAPÊUTICA SOBRE CANDIDÍASE VULVOVAGINAL
Authors: Dos Anjos Genivaldo Alves , Pereira Vinícius Soares , Hori Juliana Issa , Rodrigues Andressa Romualdo
Published: April 2023

A candidíase vulvovaginal, é uma infecção da vulva e vagina causada por vários tipos de Candida spp. Essa patologia afeta 75% de todas as mulheres pelo menos uma vez durante a vida, ocorrendo com mais frequência durante a idade fértil. A transmissão dessa infeção fúngica ocorre por meio de contato com mucosas e secreções em pele de portadores ou doentes, contato sexual, água contaminada e transmissão vertical. Alguns outros sintomas característicos mais vistos em casos de CVV, são lesões brancas, cremosas e planas, sendo mais intensos no período pré-menstrual, quando a acidez vaginal aumenta. numerosos antifúngicos estão disponíveis no mercado, os quais são encontrados para administração oral na forma de comprimidos ou, para uso tópico, na forma de cremes, loções, comprimidos vaginais, supositórios e tampões revestidos. O objetivo geral do trabalho foi analisar através da revisão de literatura, tratamentos convencionais e alternativos para abordagem terapêutica da Candidíase Vulvovaginal contextuando a mesma, utilizando definições, dados epidemiológicos e sua sintomatologia frente à sociedade. O presente trabalho é uma revisão integrativa, que teve a coleta de dados realizada de março de 2021 a outubro de 2021 nas bases de dados Lilacs, Scielo, Google acadêmico, A busca resultou em 902 artigos, dos quais 14 atenderam ao critério de inclusão. A busca por tratamentos frente a candidíase vulvovaginal tem se mostrado ampla de acordo com os artigos selecionadas. Concluímos que a patologia candidíase vulvovaginal, vem apresentando resistência em algumas abordagens terapêuticas, assim como algumas mulheres não aderem há algum tipo de tratamento, devido à falta de conhecimento sobre a patologia.
PENINGKATAN KOMPETENSI PERUM PERHUTANI DIVISI REGIONAL JAWA BARAT DAN BANTEN DALAM PRODUKSI KONTEN DIGITAL PARIWISATA DI SOSIAL MEDIA
Authors: Wijaksono Dimas Satrio , Nugrahani Rah Utami , Nurfebiaraning Sylvie , Dirgantara Pradipta
Published: April 2023

Pandemi Covid-19 dan himbauan physical distancing, membuat para pengelola destinasi wisata merasa kualahan dalam menghidupkan sektor pariwisata. Perum Perhutani Divre Jabar Bante mendukung secara khusus karena pihak Perum Perhutani Divre Jabar Banten memiliki beberapadaerah ekowisata yang menjadi kebanggan masyarakat Jawa Barat.. Berdasarkan wawancara kepadasalah satu volunteer Perum Perhutani Divre Jabar Banten, teridentifikasi beberapa kendala yangdialami dan dihadapi dalam rangka bertahan di tengah pandemi. Turunnya jumlah kunjunganwisatawan ke ekowisata yang dikelola Perum Perhutani Divre Jabar Banten membuat neracakeuangan Perum Perhutani Divre Jabar Banten menjadi defisit karena beban cost operasional yangharus ditanggung selama pandemi ini. Berdasarkan permasalahan dan potensi yang sudah diuraikandi atas, maka solusi yang bisa diterapkan adalah menyamakan persepsi masyarakat lebih dulumengenai urgensitas mempertahankan keberadaan Perum Perhutani Divre Jabar Banten sebagaisitus budaya Jawa Barat baik melalui media massa secara umum maupun langsung mengarah padapenggunaan social media khususnya Instagram dengan membuat kampanye social melalui videostorytelling dan kampanye komunikasi lingkungan. Hal ini bertujuan membuka awarenessmasyarakat mengenai kiprah Perum Perhutani Divre Jabar Banten memajukan kesenian dan budayakhas Jawa Barat serta menjadi kewajiban bagi masyarakat Indonesia untuk turut serta melestarikanbudaya bangsa. Kata kunci: kampanye social, videostorytelling, event virtual.
SOSIALISASI INTERNET SEHAT UNTUK PD. SALIMAH KOTA BANDUNG
Authors: Rosmiati Mia , Brotoharsono Tri , M. Mandasari Rizza Indah
Published: April 2023

Kegiatan Sosialisasi Internet sehat untuk komunitas Salimah merupakan sebuah kegiatan Pengabdian Masyarakat yang diadakan Untuk meningkatkan pengetahuan dan pemahaman dalam menggunakan internet secara sehat dan aman. Hal ini dikarenakan  Peserta kegiatan ini berasal dari Komunitas Salimah yang  beranggotakan perempuan dan Sebagian besar sudah berumah tangga dan memiliki anak, sehingga kegiatan yang dilaksanakan melalui sharaing session diharapkan dapat memberikan informasi terkait ancaman dan bahaya pada saat menggunakan internet serta Tips dan Trik penggunaan internet yang aman bagi seluruh anggota seluruh anggota keluarganya. Kegiatan sosialisasi internet sehat ini dilaksanakan melalui dua sesi presentasi menggunakan aplikasi power point dan aplikasi youtube yaitu sesi pertama terkait dengan pengunaan internet sehat. Sesi ini berisi informasi terkait dampak positif dan negative  yang sering muncul pada saat menggunakan internet serta teknik yang aman  menggunakan Internet. Sesi kedua merupakan sosialisasi penggunaan gadget yang bijak. Adapun alasan diangkatnya topik ini dikarenakan hampir semua orang saat ini sudah memiliki dan menggunakan gadget bahkan rata-rata hampir 70% dalam waktu keseharianya tidak pernah lepas dari gadget. Hal ini memberikan dampak negatif terhadap kondisi social maupun emosinalnya. Oleh karena itu melalui kegiatan pengabdian masyarakat sesi 2 ini diharapkan peserta dapat mengendalikan penggunaan gadgetnya secara bijak. Sedangkan proses tanya jawab dilaksanakan pada kegiatan sesi 3, melalui kegiatan ini peserta dapat memperjelas materi yang disampaikan pemateri melalui kegiatan diskusi  interaktif.. berdasarkan kuisioner yang telah disebarkan kepada 16 peserta, menunjukkan bahwa 100% peserta menyatakan kegiatan ini sangat bermanfaat dan sesuai dengan kebutuhan dari peserta pengabdian masyarakat, sehingga diharapkan kegiatan yang dapat meningkatkan pemahaman dan teknik terbaru dalam pemanfaatan internet dapat dilanjutkan untuk kegiatan berikutnya.  Kata Kunci: Internet sehat, Gadget, sosialisasi