bluuebunny/crossref_metadata_2025 huggingface dataset:
Utility of 18F-fluorodeoxyglucose PET-CT scan in detecting bone marrow involvement in lymphoma
Authors: Jitani Ankit Kumar , Dutta Shyamali , Mandal Prakas Kumar , De Rajib , Jajodia Ekta , Baul Shuvraneel , Chakrabarti Prantar , Dolai Tuphan Kanti
Published: June 2022

Background & objectives:

Evaluation of bone marrow infiltration in lymphoma is usually done by bone marrow biopsy (BMB). This study analyzed the utility of 18F-fluorodeoxyglucose positron emission tomography/computerized tomography (18F-FDG PET/CT) to detect bone marrow involvement (BMI) compared to BMB.

Methods:

Treatment-naïve lymphoma patients underwent both 18F-FDG PET/CT scan and BMB before treatment initiation. BMI detected on PET/CT was compared with BMB.

Results:

The study population consisted of 80 patients and comprised 37 Hodgkin’s lymphoma (HL) patients, 30 aggressive non-HL (NHL) and 13 indolent NHL patients. The majority of the aggressive NHLs were diffuse large B-cell lymphoma (20/30) and major indolent lymphoma was follicular lymphoma (5/13). When compared to BMB, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of focal (±diffuse) marrow FDG uptake on 18F-FDG PET/CT were 100, 61.3, 33.3 and 100 per cent, respectively, for HL; 100, 65.4, 30.8 and 100 per cent, respectively, for aggressive NHL and 75, 80, 85.7 and 66.7 per cent, respectively, for indolent NHL. When comparing marrow involvement on 18F-FDG PET/CT to baseline BMB and/or resolution of bone marrow FDG uptake at interim/end-of-treatment 18F-FDG PET/CT, the sensitivity, specificity, PPV and NPV were 100 per cent each for HL and aggressive NHL and 77.3, 100, 100 and 66.7 per cent, respectively, for indolent NHL.

Interpretation & conclusions:

18F-FDG PET/CT has a good sensitivity and NPV for detecting BMI in HL and aggressive lymphoma. The low specificity and PPV improved if marrow uptake pattern on interim or end-of-treatment 18F-FDG PET/CT scan was analyzed. In patients with HL who are staged with18F-FDG PET/CT at baseline and followed up with an interim/end-of-treatment PET/CT, baseline BMB may be avoided. For all other lymphoma subtypes, BMB may be essential if there is no marrow FDG uptake on PET/CT scan performed at baseline.
The species distribution of ticks & the prevalence of Kyasanur forest disease virus in questing nymphal ticks from Western Ghats of Kerala, South India
Authors: Balasubramanian R. , Yadav Pragya D. , Sahina S. , Nadh V. Arathy
Published: June 2022

Background & objectives:

Kyasanur forest disease (KFD) is a zoonotic tick-borne disease across the Western Ghats of India. With the discovery of a cluster of human KFD cases in the Wayanad district of Kerala, the present study was focused on detecting KFD virus (KFDV) in tick populations. To manage this disease, it is necessary to understand the diversity of the tick species and factors influencing the distribution, abundance and prevalence of infected ticks in Wayanad district.

Methods:

Surveys were conducted from November 2016 to May 2018 in four forest ranges of Wayanad district. Ticks were collected by the dragging method and were identified to species level and assayed for virus detection using real-time polymerase chain reaction.

Results:

A total of 25,169 ticks were collected from 64 sites. Of the identified species, Haemaphysalis spinigera was the most abundant (56.64%), followed by H. turturis 9047 (35.94%), H. bispinosa 999 (3.96%), Amblyomma integrum 691 (2.74%), H. kyasanurensis (0.55%), Rhipicephalus sanguineus (0.08%), Hyalomma marginatum (0.02%), H. cuspidata (0.01%), R.microplus (0.01%) and Dermacentor auratus (0.003%). The nymphal stage was predominant from December to February having peak activity in January. A total of 572 pools were screened for the presence of KFDV, of which 21 pools were positive. The infection rates in H. spinigera and H. turturis tick were 2.62 and 1.04 per cent, respectively.

Interpretation & conclusions:

The circulation of KFDV was detected and its correlation with the prevalence in ticks near the fragmented forest and teak plantation areas of Wayanad district. Residents and visitors of these regions may become vulnerable to tick bites and to an increased risk of KFD as the distribution of established, infected tick populations continues to expand.
Lactate enhanced-quick Sequential Organ Failure Assessment 2 (LqSOFA2): A new score for bedside prognostication of patients with sepsis
Authors: Daga Mradul Kumar , Rohatgi Ishan , Mishra Rashmi , Kumar Naresh , Mawari Govind , Mishra T.K. , Singh Shashank , Shukla Jitendra
Published: June 2022

Background & objectives:

Early diagnosis and prompt treatment remain a challenge in sepsis. To study the role of quick Sequential Organ Failure Assessment (qSOFA), blood lactate levels and a new score Lactate - Enhanced-qSOFA 2 (LqSOFA2) in predicting outcome in patients with sepsis and their association with established severity scores.

Methods:

This was a prospective, observational study in patients admitted to ICU of a tertiary care hospital in north India. qSOFA, Acute Physiology and Chronic Health Evaluation II (APACHE II), SOFA score and LqSOFA2 were calculated in 150 patients with sepsis. Measurements of lactate and SOFA score was done on days one, three and seven.

Results:

The mean arterial pressure (MAP) was significantly higher in survivors (70.14±19.54 vs. 48.53±26.86). The mean qSOFA significantly predicted mortality (1.81 vs. 2.63; P<0.0001). The mean lactate on days one, three and seven in survivors were 2.27±0.91, 1.72±0.77 and 1.14±0.48, respectively, while it was 4.32±2.35, 3.57±2.28 and 2.13±1.22, respectively, in the non-survivor group (P<0.001). The new score LqSOFA2 also significantly predicted mortality between non survivors and survivors (3.52±0.71 vs. 2.37±0.91). There was a significant correlation of qSOFA with SOFA and APACHE II on day one. Lactate levels and SOFA correlated on all three days.

Interpretation & conclusions:

qSOFA, a novel score and lactate can independently predict mortality in patients with sepsis. They correlate with APACHE II and SOFA but fail to equilibrate with either. The combination score LqSOFA2 showed marginal (statistically insignificant) increase in predictive accuracy and specificity when compared to lactate or qSOFA alone. Early diagnosis by LqSOFA2 makes it a good standalone bedside prognostic marker.
Prevalence, pattern & correlates of hypertension among tribal population of Kashmir, India
Authors: Ganie Mohd Ashraf , Parvez Tabassum , Viswanath S. Arun , Sreenivas Vishnubhatla , Ramakrishnan Lakshmy , Nisar Sobia , Sahar Tajali , Robbani Irfan , Ali Shiekh Abid , Rashid Aafia , Wani Ishfaq Ahmad
Published: June 2022

Background & objectives:

The prevalence of hypertension is increasing among all ethnic groups across the globe with only a handful of studies from India addressing the prevalence of hypertension among tribal population. In view of paucity of data, this study was aimed at estimating the prevalence of hypertension and associated risk factors among tribal population of Kashmir, India.

Methods:

This cross-sectional survey included 6808 tribals aged >20 yr (5695 Gujjars and 1113 Bakarwals) from five randomly selected districts of Kashmir. Modified WHO-STEPS surveillance questionnaire was used to collect relevant data. Hypertension was defined by Joint National Committee on Prevention, Detection, Evaluation and Treatment of Hypertension (JNC 8) criteria.

Results:

The mean age of our study participants was 43.12 ± 15.69 years. Overall prevalence of hypertension [95% confidence interval (CI)] was 41.4% (39.9-42.9%) [men=46.7% (44.1-49.1%); women=37.9% (35.9-39.9%)]. The prevalence of prehypertension (95% CI) in our study was 35 per cent (33.7-36.6%). Higher age [adjusted odds ratio (OR) (95% CI): >70 yr-2.2 (1.9-2.4)], passive smoking [OR-1.3 (1.1-1.5)], family history of hypertension [OR-1.6 (1.4-1.7)] and obesity [OR-1.3 (1.1-1.6)] were significantly associated with hypertension. A weak positive correlation was observed between BP (systolic/diastolic) with haemoglobin, red blood cell count and haematocrit (P<0.05).

Interpretation & conclusions:

Gujjar and Bakarwal tribes of Jammu and Kashmir showed high prevalence of hypertension. Hence, urgent policies and reforms are needed to tackle this silent epidemic and further studies focusing on community-based interventions are required.
Plasminogen activator inhibitor-1 promoter sequence variations in idiopathic osteonecrosis of head of femur
Authors: Raman Srishty , Dada Rima , Nag Tapas Chandra , Yadav Chandra Shekhar
Published: June 2022

Background & objectives:

Primary or idiopathic osteonecrosis of femur head (ONFH) is the second most commonly observed cause among Indian patients suffering from ischemic ONFH. Although a number of genetic polymorphisms have been associated with idiopathic ONFH pathogenesis in Korean and Chinese populations, there are no studies in the Indian population. This is an exploratory study designed to implicate in promoter sequence polymorphisms of a critical fibrinolytic system regulator, plasminogen activator inhibitor-1 (PAI-1) gene, in cases of idiopathic osteonecrosis. Promoter sequence variations can affect expression levels of PAI-1 gene and may disrupt the coagulation/fibrinolytic equilibrium, which may finally culminate into osteonecrosis. Hence, the aim of the study was to investigate the role of single-nucleotide polymorphisms (SNPs) in the promoter region of PAI-1 gene and osteonecrosis development.

Methods:

Two SNPs of the PAI-1 gene (rs2227631, -844 G/A; rs1799889, -675 4G/5G) were genotyped in 25 patients diagnosed with idiopathic ONFH and 25 control subjects, using direct sequencing. Subsequently, association analyses were performed for the genotyped SNPs.

Results:

Both the rs2227631 and rs1799889 genotype and allele frequencies of PAI-1 gene showed an insignificant association with osteonecrosis risk (P=0.717, 0.149). Haplotype frequencies of rs2227631 and rs1799889 were also calculated in patients having idiopathic ONFH and controls. Although the distribution of haplotype GA-4G 4G was found to be the highest among the cases, it was not significantly different when compared with the controls.

Interpretation & conclusions:

Our findings demonstrate that the minor alleles of promoter region sequences of the PAI-1 gene do not contribute to an increase in ONFH predisposition. However, this is a preliminary study and its findings should be considered as suggestive for studies to be done in a larger sample size.
Maternal near miss events in India
Authors: Kulkarni Ragini , Kshirsagar Harshal , Begum Shahina , Patil Anushree , Chauhan Sanjay
Published: June 2022

Background & objectives:

Maternal morbidity is an indicator of the quality of a country’s maternal health services. Maternal near miss (MNM) can provide valuable information in this context and hence these cases need to be reviewed which can indirectly play a major role in reducing maternal mortality ratio in India. The objectives of the present review were to find the prevalence/incidence, criteria used for identification, review the causes of MNM cases and identify the contributory factors responsible for the occurrence of these cases based on three-delay model.

Methods:

Articles were identified from the PubMed, Google Scholar, Scopus and Cochrane Library using search terms such as ‘Maternal Near Miss’,‘maternal morbidity’, ‘India’ among others. All health facility-based observational studies conducted in India published between 2010 to 2019 irrespective of data collection period, and criteria used for identification of MNM cases were included for review. Data were extracted from included studies and summarized in terms of prevalence/incidence, ratio and percentage.

Results:

Out of 25 studies, majority were prospective observational conducted at government health facilities. The incidence of MNM varied widely from 3.9 to 379.5 per 1000 live births and 7.6-60.4 per 1000 deliveries. MNM: Maternal Death varied from 1.7:1 to 21.8:1; studies used different criteria to define MNM cases.

Interpretation & conclusions:

Hypertensive disorders and anaemia were the leading direct and indirect causes of MNM, respectively. There was a lack of uniformity in using the criteria for MNM across studies conducted in India over the last decade. Future studies on MNM in India should follow the uniform criteria mentioned in the MNM-Review guidelines released by the Government of India in 2014 for obtaining systematic data and proper summary estimates.
Survey of autism spectrum disorder in Chandigarh, India
Authors: Arun Priti , Chavan Bir Singh
Published: June 2022

Background & objectives:

Prevalence of autism spectrum disorder (ASD) has been reportedly on the rise in western literature. However, accurate data from India are not available. The present study was planned to assess the community-based prevalence of ASD in Chandigarh, India.

Methods:

This study was a two-stage survey of representative child population of Chandigarh using stratified random sampling technique, covering 8820 children between the ages 1.5 and 10 yr. Proportionate population from urban (82.3%), rural (4.3%) and slum area (13.4%) were included in the study and screened using Chandigarh autism screening instrument (CASI). Thirty two children scored above cut-off, of whom two had shifted to other places before they could be assessed and 30 were assessed in detail. Detailed assessment was done using Autism Diagnostic Interview–Revised and Childhood Autism Rating Scale-2; diagnosis was made according to the Diagnostic and Statistical Manual-5. Nineteen were diagnosed with ASD.

Results:

Of the 8451 children screened between the age group of one and a half to 10 yr, 19 (10 boys and 9 girls) were diagnosed as ASD, thus the prevalence of ASD was found to be 2.25 per 1000 (0.69-5.19, 95% confidence interval) children in Chandigarh. No child below the cut-off on the screening instrument was diagnosed as ASD.

Interpretation & conclusions:

The results suggest that the prevalence of ASD in Chandigarh was in tandem with other reports from across India and was lower than western countries.
Case Report: Laparoscopic Management of Acute Appendicitis Resulting from Ascaris lumbricoides
Authors: Castañeda Catalina , Valbuena Diego , Salamanca William , Acevedo David , Pedraza Mauricio
Published: June 2022

Appendicitis is one of the most common conditions that leads to an acute abdomen. Surgical management is the gold standard for therapy. The main cause of appendicitis is an obstruction in the appendicular lumen. Intestinal ascariasis infection is undoubtedly one of the least frequent. We present a female patient with acute appendicitis resulting from Ascaris lumbricoides as an incidental intraoperative diagnosis.
Routine Healthcare Facility– and Antenatal Care–Based Malaria Surveillance: Challenges and Opportunities
Authors: Gutman Julie R. , Thwing Julie , Mwesigwa Julia , McElroy Peter D. , Robertson Molly
Published: June 2022

Most monitoring and evaluation tools for measuring malaria burden, intervention coverage, and impact of interventions use periodic nationally representative cross-sectional household surveys. These provide advantages in terms of selecting a large, unbiased, population-based sample; however, they are infrequently conducted, are resource-intensive, and do not provide longitudinal data with sufficient granularity. Given the heterogeneity of malaria transmission within most endemic countries, systems with the capacity to provide more granular and frequent data would be more actionable by national malaria control programs and local implementing partners. There is increasing interest in using routine health facility data, usually from outpatient department visits, for monitoring malaria burden. Data from pregnant women attending antenatal care (ANC) could minimize bias related to fever care-seeking among outpatient department visits and provide more granular parasite prevalence data. Most pregnant women attend ANC at least once and are thus highly representative of the overall pregnant population. A growing body of evidence suggests that malaria parasitemia in pregnant women is correlated with parasitemia in children aged < 5 years in moderate to high transmission areas, allowing for monitoring parasitemia in real time. Additional data are needed to assess whether pregnant women are sufficiently representative of the overall population to yield valid malaria prevalence and intervention coverage estimates. Although use of routinely collected ANC data faces many of the same challenges experienced by other routinely collected health facility data, the opportunity to improve parasite prevalence monitoring and the associated health benefits to mothers and infants of early detection of parasitemia make these efforts valuable.
Toward a Machine Learning Development Lifecycle for Product Certification and Approval in Aviation
Authors: Kaakai Fateh , Dmitriev Konstantin , Adibhatla Sridhar , Baskaya Elgiz , Bezzecchi Emanuele , Bharadwaj Ramesh , Brown Barclay , Gentile Giacomo , Gingins Corinne , Grihon Stephane , Travers Christophe
Published: June 2022

This article presents a new machine learning (ML) development lifecycle which will constitute the core of the new aeronautical standard on ML called AS6983, jointly being developed by working group WG-114/G34 of EUROCAE and SAE. The article also presents a survey of several existing standards and guidelines related to ML in aeronautics, automotive, and industrial domains by comparing and contrasting their scope, purpose, and results. Standards and guidelines reviewed include the European Union Aviation Safety Agency (EASA) Concept Paper, the DEEL (DEpendable and Explainable Learning) white paper “Machine Learning in Certified Systems”, Aerospace Vehicle System Institute (AVSI) Authorization for Expenditure (AFE) 87 report on Machine Learning, Guidance on the Assurance of Machine Learning for use in Autonomous Systems (AMLAS), Laboratoire National de Metrologie et d’Essais (LNE) Certification Standard of Processes for AI, the Underwriters Laboratories (UL) 4600 Safety Standard for Autonomous Vehicles, and the paper on Assuring the Machine Learning Lifecycle. These standards and guidelines are examined from the perspective of the learning assurance objectives they propose, and the means of evaluation and compliance for achieving these learning objectives. The reference used for comparison is the list of learning assurance objectives defined within the framework of AS6983 development. From this comparative analysis, and based on a coverage criterion defined in this article, only three (3) standards and guidelines exceed 50% coverage of the Machine Learning Development Lifecycle (MLDL) learning assurance objectives baseline. The next steps of this work are to update the AS6983 learning assurance objectives and improve the associated means of compliance to approach a coverage score of 100%, and offer a certification-based process to other domains that could benefit from the AS6983 standard.
Evaluation of the Heat Transfer Performance of Stearic Acid PCM/ Porous Aluminium Thermal Composite Structures for Heat Storage Applications
Authors: Egwuonwu Njoku, Romanus
Published: June 2022

Phase change material (PCM) thermal composites consisting of porous aluminium/stearic acid phase change material have been produced for heat storage applications. Porous aluminium/stearic acid composite structures were produced by infiltrating stearic acid PCM into open- cell porous aluminium materials prepared by using dissolvable spherical salt beads in combination with vacuum casting process. Scanning electron microscopic analysis has been used to characterize the empty porous aluminium materials and the results reveal a cellular structure consisting of spherical pores which are interconnected with smaller windows. The thermal response of empty porous aluminium structures and those infiltrated with stearic acid was measured using an infrared camera. The result showed that the heat transfer performance of the PCM thermal composites was significantly improved and largely dependent on the relative density of the porous structures.
Evaluation of biochemical markers in the blood plasma of rats exposed to chronic administration of a mixture of metal nanoparticles
Authors: Romanko Maryna , Orobchenko Oleksandr , Palliy Anatoliy , Ushkalov Valerii , Palii Andrii , Chechui Helena
Published: June 2022

The aim of this study was to determine the effects of a specific mixture of metal nanoparticles (Ag, Cu, Fe and MnО2) orally administered to rats, on biochemical blood markers as indicators of chronic toxicity. Animals (Wistar line rats (n=20)) in experimental groups were given a solution of a mixture of metal salts or a mixture of nanoparticles with food for 90 days. On days 15, 30, 60 and 90 of the experiment, five rats from each group were anaesthetised with CO2 and decapitated, and blood samples were collected for biochemical studies and spectrophotometric measurement. The toxic effect of the chronic administration of the mixture at a dose of 4.0 mg/kg of body weight in white rats caused partial immunosuppression expressed as hypoproteinaemia, excessive formation of circulating immune complexes and acute phase serum mucoid proteins (P<0.05), and cytolytic damage to hepatocyte membranes. Levels of enzyme activity (AST, GGT, ALT and AP) were significantly elevated (P<0.05). It has been shown that the origin of the toxic effect is due to oxidative stress, which slowed lipoperoxidation along with the elevation of the level of carboxylated proteins, depleting the antioxidant defence resources of the organism, as seen by a decrease in the level of catalase and total antioxidant activity (P<0.05). No such effects were observed at the dose of 0.3 mg/kg as there were no significant negative impacts on the biomarkers. Based on this data, the biochemical markers studied may be suitable for use in pre-clinical in vivo toxicological assessment of metal nanoparticle-candidates for pharmaceuticals.
Eustrongilidoza riba
Authors: Oraić Dražen , Zupičić Ivana Giovanna , Zrnčić Snježana
Published: June 2022

Oblići roda Eustrongylides se nalaze širom svijeta u brojnih riba slatkovodnih i morskih ekosustava. Sve vrste ovih u riba opisanih parazita imaju neizravni razvojni ciklus te su ribe drugi međudomaćin ili paratenični nositelj i plijen ribojednih ptica koje su konačni domaćini. Eustrongilidi su oblikom okrugli, glatki, relativno dugački crvi zbog prisustva hemoglobina crvene boje. Veći broj ličinki parazita u ribi može izazvati teške oblike bolesti, utjecati kod nekih vrsta na plodnost i povećati smrtnost. Za dijagnozu eustrongilidoze sigurna metoda je razudba male grupe zaraženih riba te mjesta nalaza i karakteristike parazita u ribi. Potrebno je isključiti druge parazite riba - crve plošnjake, segmentirane trakavice, jednorodne i dvorodne metilje te akantocefale. Za prevenciju eustrongilidoze u riba potrebno je u nekom od razvojnih stadija prekinuti životni ciklus parazita za što je potrebno ukloniti bilo kojeg međudomaćina ili konačne domaćine. Za uzgajane ribe, sanitacija ribnjaka omogućava prevenciju zaraze ribe od ovih parazita. Eustrongilidi riba su identificirani kao uzročnici infekcije ljudi kao slučajnih domaćina te iako je opisan mali broj kliničkih slučajeva, eustongilidoza je priznata zoonoza. Da bi se spriječila infekcija ljudi preporuka je izbjegavati konzumiranje sirove ribe i sirovih ribljih proizvoda. Učinkovita metoda ubijanja parazita je temeljita termička obrada.
Evaluatıon of Care Load and Emotıonal Intellıgence Level of Care for Cancer Patıents
Authors: ÖZDEMİR GÖZDE , ÖZKARAMAN Ayşe
Published: June 2022

Objective: This research is a cross-sectional study sesigned to evaluate the caregiving burden and emotional intelligence level of individuals caring for cancer patients. Materials-methods: The research was carried out between 01.11.2017-31.12.2018 in Medical Oncology, Hematology clinic and polyclinics. The sample of the study consisted of 238 caregivers over the age of 18 who could read and write in Turkish, , and volunteered to participate in the study. Research data were collected using personal data collection form, Schutte Emotional Intelligence Scale and Zarit Care Burden Scale. Research data were analyzed with Spearman Correlation analysis, Kruskal Wallis Test, Dunn's Test and Mann Whitney U tests. Results: In the study, 63% of the caregivers were female, 40.3% were between the ages of 20-40, most of them are high school graduates (30.7%) and married (64.3%). The total median point of caregivers care burden interview is 44.97 (21.00-82.00) and the total median point of the emotional intelligence scale is 160.49±16,181. The median score of caregivers' burden of care, according to education level, family type, income status, place of residence and treatment applied to the patient; Emotional intelligence total median score differs statistically significantly according to education level and place of residence (p<0.05). In the study, a weak positive correlation was found between the caregiving burden median score and the emotional intelligence median scores (r=0.240; p<0.005). Conclusion: In this study, moderate caregiving burden was determined in caregivers of cancer patients. It was determined that the caregiver burden and emotional intelligence level of caregivers were affected by some socio-demographic factors, and as the level of emotional intelligence increased, the burden of care increased.
Correct Mask Usage Status, Pandemıc Perceptıon and Affectıng Factors in The Covıd-19 Pandemıc Process
Authors: önal özgür , Batmaz Kıymet , Çoban Betül , Yıldırım Uz Ayşe , Güblü Merve , Uskun Ersin , Kişioğlu Ahmet Nesimi
Published: June 2022

Introduction: In this study, it was aimed to examine the factors affecting the correct use of masks and pandemic perception during the COVID-19 pandemic process. Materials and Methods: In the study, together with the use of the correct mask, socio-demographic characteristics, attitudes and behaviors towards the use of masks, knowing and applying the precautions to prevent the epidemic, following the number of cases in Turkey and in the world, seeing the pandemic as lethal and contagious, seeing the restrictions applied as necessary, frequency of hand washing compared to the pre-pandemic period and An increase in the stress level, a decrease in the frequency of home visits and a different intervention to the products brought to the house were examined. Results: In this study, those who said that they always used a mask in communicating with people during the pandemic process were 54.4%, and 91.6% said that they used the mask like cover their mouth and nose. However, according to the observations of the researchers, the frequency of correct use of masks was found to be 64.0%. Although 93.2% of the participants thought it necessary to use a mask, 20.0% of them stated that they used a mask because it was forbidden. 87.6% of the people said that the pandemic actually existed and was of significant size, 12.4% said the pandemic was present, but it was insignificant or that there was no pandemic. In the multiple analyzes made; The opinion that the pandemic is real and significant in people over the age of 50, people who find the contagiousness of the microorganism high, people who follow the number of cases in the country and volunteer to wear a mask for protection although it is not prohibited, was found to be significantly high. The correct use of masks was found to be significantly higher in individuals who had know persons with COVID-19 and found the lethality of the pandemic high. Conclusion: Although the use of masks was found to be high in our research area, the correct use of masks is not sufficient. However, it can be said that people's perception of the pandemic is at a sufficient level.
Đặc điểm lâm sàng, cận lâm sàng ở bệnh nhân có kết quả tế bào âm đạo – cổ tử cung LSIL khám tại Bệnh viện Phụ sản Trung ương
Authors: Trần Thị Ly , Trần Thị Thu Hạnh , Nguyễn Mạnh Thắng
Published: June 2022

Mục tiêu: Mô tả đặc điểm lâm sàng, cận lâm sàng các bệnh nhân có kết quả tế bào âm đạo – cổ tử cung LSIL.

Đối tượng và phương pháp: Tiến cứu mô tả trên 110 bệnh nhân khám sàng lọc ung thư cổ tử cung bằng tế bào âm đạo – cổ tử cung đơn thuần, có kết quả là LSIL từ 01/10/2020 đến 31/03/2021 khám tại Bệnh viện Phụ sản Trung ương.

Kết quả và kết luận: Có 43,6% bệnh nhân có ra khí hư nhiều, 15,5% ra máu bất thường và có tới 22,7% bệnh nhân không có triệu chứng lâm sàng. Soi cổ tử cung có 60,8% có tổn thương nghi ngờ. Khi khám lâm sàng có 12,7% trường hợp có tổn thương nghi ngờ ung thư cổ tử cung. Bệnh nhân LSIL chủ yếu có các tổn thương lành tính, CIN I, CIN II (68,9%) và có kết quả HPV âm tính hoặc dương tính 1/12 type nguy cơ cao. Bệnh nhân LSIL ≥ 40 tuổi có nguy cơ mắc CIN III hoặc ung thư biểu mô vảy cao gấp 1,22 lần so với nhóm dưới 40 tuổi với p < 0,001. Những bệnh nhân này chủ yếu nhiễm HPV typ 16 và/hoặc type 18 (p < 0,05).
Thái độ xử trí thai làm tổ vết mổ cũ dựa trên hình ảnh siêu âm tại Khoa Phụ ngoại Bệnh viện Phụ sản Trung ương từ 01/2021 - 6/2021
Authors: Trương Quốc Việt , Trần Danh Cường , Nguyễn Thị Huyền Trang , Trần Thị Định , Nguyễn Thị Xuân Hảo
Published: June 2022

Mục tiêu: Đánh giá thái độ xử trí thai làm tổ vết mổ cũ dựa trên hình ảnh siêu âm.

Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả trên 67 trường hợp bệnh nhân được chẩn đoán thai làm tổ vết mổ cũ tại Khoa Phụ Ngoại.

Kết quả: Trong số 67 trường hợp thai làm tổ vết mổ cũ, số bệnh nhân đã mổ lấy thai 1 lần: 15/67 (22,4%) và ≥ 2 lần: 52/67 (77,6%). Xử trí ban đầu là: hút thai đơn thuần: 29,9%, hút thai kết hợp bóng chèn: 43,3% và 19,4% chỉ định phẫu thuật. Tỷ lệ thành công của nhóm hút đơn thuần là 100%, và của hút thai phối hợp đặt bóng chèn là 82,8%, có 5 trường hợp thất bại chuyển phẫu thuật. Tỷ lệ thành công của các trường hợp phẫu thuật đạt 100%, không có trường hợp nào phải cắt tử cung.

Kết luận: Xử trí sớm các trường hợp thai ở sẹo mổ cũ lấy thai khi chẩn đoán được. Kết hợp nhiều phương pháp trong điều trị dựa vào hình ảnh siêu âm để đạt hiệu quả cao nhất. Siêu âm đường bụng nhịn tiểu là phương pháp giúp chẩn đoán thai làm tổ vết mổ cũ hiệu quả.
Making Food Waste Socially Unacceptable: What Behavioral Science Tells Us About Shifting Social Norms to Reduce Household Food Waste
Authors: Blondin Stacy , Attwood Sophie
Published: June 2022

This working paper summarizes the methodology and results from two original randomized controlled trials that reached more than 40 million consumers in order to assess the impact of social norms messaging on consumers’ knowledge, attitudes, beliefs, and behaviors around food waste. It finds that making food waste socially unacceptable through the right type of messaging can elevate the importance of this issue in consumers’ lives. While social norms messages, by themselves, are not a panacea for eliminating consumer food waste, they can contribute to significant reductions in waste when included in multicomponent interventions. The paper provides 10 insights that can be incorporated into campaigns led by nongovernmental organizations, local and national governments, and businesses aiming to help reduce household food waste.
Pengaruh Tingkat Kesejahteraan, Lingkungan Kerja Fisik, Dan Disiplin Kerja Terhadap Kinerja Karyawan Kampung Ubud Hotel
Authors: Herlambang Putu Gede Denny , Sukanti Ni Ketut , Mandiyasa I Kadek Sara , Wijaya Bagus Arya
Published: June 2022

Kinerja seorang karyawan bersifat individual, karena setiap karyawan mempunyai tingkat kemampuan yang berbeda-beda dalam mengerjakan tugasnya. Kinerja karyawan dapat dipengaruhi oleh tingkat kesejahteraan, lingkungan kerja fisik, dan tingkat kedisiplinan karyawan dalam perusahaan. Kesejahteraan adalah balas jasa secara material maupun non material untuk memperbaiki kondisi fisik dan mental karyawan. Lingkungan kerja fisik adalah semua keadaan berbentuk fisik yang terdapat di tempat kerja. Kedisiplinan seseorang dalam bekerja dapat dilihat dari kesadaran dan kesediaan seseorang mentaati SOP perusahaan. Tujuan penelitian adalah untuk mengetahui pengaruh secara parsial maupun simultan antara tingkat kesejahteraan, lingkungan kerja fisik, dan disiplinakerja secara simultan terhadap kinerja karyawan pada Kampung Ubud Hotel. Jumlah sampel yang ditentukan dengan metode sampel jenuh adalah 35 responden. Instrumen penelitian diuji menggunakan uji validitas dan uji reliabilitas. Data dianalisis uji asumsi klasik untuk model regresi dan uji regresi linear berganda sebagai pengujian hipotesis. Hasil penelitian menunjukkan bahwa secara parsial tingkat kesejahteraan tidak berpengaruh terhadap kinerja karyawan, namun lingkungan kerja fisik dan disiplin kerja berpengaruh positif signifikan pada kinerja karyawan. Secara simultan tingkat kesejahteraan, lingkungan kerja fisik, dan disiplin kerja berpengaruh positif dan signifikan terhadap kinerja karyawan pada Kampung Ubud Hotel.
Pengaruh Pandemi Covid-19 Terhadap Pariwisata Bali
Authors: Amrita Nyoman Dwika Ayu , Handayani Made Mulia , Erynayati Luh
Published: June 2022

Pandemi Covid-19 membawa dampak yang sangat signifikan terhadap semua aspek perekonomian termasuk pariwisata. Khusus untuk Provinsi Bali, dampak ini sangat terasa dan berpengaruh mengingat Bali merupakan destinasi pariwisata utama. Larangan bepergian dan ketakutan akan penyebaran virus membuat jumlah turis domestik dan turis asing menurun drastis. Penelitian ini menggunakan metode kualitatif. Penelitian ini menggunakan data sekunder dari berbagai literatur seperti buku, artikel, laman internet dan materi webinar untuk mengakses data dan informasi terkini terkait dampak pandemi Covid-19 terhadap pariwisata Bali. Upaya-upaya telah dilakukan untuk memulihkan semua tujuan wisata yang terkena dampak, termasuk program CHS (Cleanliness, Health, and Safety) dan meminimalkan kontak fisik (contactless) di semua proses bisnis di industri pariwisata, termasuk pembayaran. Dengan menggunakan teknologi finansial, pariwisata dapat menerapkan proses transaksi untuk mengurangi kontak dengan wisatawan.
Pengaruh Literasi Keuangan, Inklusi Keuangan dan Akses Permodalan Terhadap Keberlanjutan UMKM Pada Bidang Fashion Di Kota Denpasar
Authors: Nugraha Sugita I Kadek Diki , Seri Ekayani Ni Nengah
Published: June 2022

Keberadaan UMKM memiliki peran penting pembangunan ekonomi suatu negara dalam mendorong pertumbuhan perekonomian Indonesia. Hal ini menimbulkan ketertarikan untuk menganalisis faktor-faktor dari keberlanjutan UMKM. Penelitian ini bertujuan menganalisis pengaruh literasi keuangan, inklusi keuangan dan akses permodalan terhadap keberlanjutan UMKM di Kota Denpasar khususnya pada bidang fashion. Populasi penelitian ini adalah para UMKM di bidang fashion yang terdaftar di Dinas Koperasi UMKM di Kota Denpasar. Sampel yang digunakan adalah sebesar 99 responden. Metode pengumpulan data adalah metode survey dengan kuesioner. Teknik analisis regresi linier berganda digunakan untuk menguji pengaruh variabel bebas terhadap variabel terikat. Hasil penelitian menemukan bahwa literasi keuangan, inklusi keuangan dan akses permodalan berpengaruh positif terhadap keberlanjutan UMKM di Kota Denpasar khususnya pada bidang fashion. Untuk meningkatkan literasi keuangan, UMKM di Kota Denpasar khususnya pada bidang fashion perlu meningkatkan pengetahuan akuntansi dasar, memahami manfaat pengelolaan keuangan, memahami pengelolaan keuangan yang efektif, mengetahui syarat agar mendapatkan pinjaman bank, mengetahui manfaat fasilitas bank, meningkatkan analisis kinerja secara berkala, membuat pembukuan kas per-hari, aktif melakukan bimbingan dan pembinaan, melakukan bugeting, menyusun anggaran belanja per-bulan, tetap berhati-hati dalam melakukan kredit ataupun pinjaman, berani mengambil resiko, dapat mengatur strategi resiko keuangan dan menetapkan planning kedepan. Untuk meningkatkan inklusi keuangan, UMKM perlu mengetahui Lembaga keuangan yang berlokasi strategis, mengetahui layanan yang diberikan bank, mampu menggunakan fasilitas  Lembaga keuangan untuk mengelola keuangan, meningkatkan penggunaan internet dalam mengakses layanan keuangan, Lembaga keuanggan perlu membuat panduan tata cara dalam mengakses layanan, layanan jasa keuangan sangat membantu para UMKM, mengoptimalkan biaya pemeliharaan serta Lembaga keuangan menyediakan produk dan layanan untuk meningkatkan pendapatan. Aspek-aspek yang perlu diperhatikan untuk meningkatkan akses permodalan adalah memudahkan memperoleh informasi terkait pinjaman dari berbagai pihak, mampu mendapat tawaran dari Lembaga keuangan untuk meningkatkan usaha, mengantisipasi hambatan dalam mengakses modal eksternal, dan tidak mempersulit pinjaman kerdit usaha rakyat.
Changes in oral health-related quality of life after treatment of molar incisor hypomineralization using Glass Hybrid Restorations
Authors: Tugcu Nihan , Sezer Berkant , Caliskan Cansu , Durmus Basak , Kargul Betul
Published: June 2022

Objective: To assess the changes in children’s oral health-related quality of life following the treatment of severely affected molar-incisor hypomineralisation with Glass Hybrid Restorative System (GH) after selective caries removal.
Method: The observational cross-sectional study was conducted at the Marmara University, School of Dentistry, Department of Pediatric Dentistry. Children aged 11–14 years (n = 55) who were diagnosed with MIH and had finished their dental treatment from November 2018 to December 2019, were included. The children’s MIH-affected teeth were treated with GH after SCR. Participants answered the Child Perceptions Questionnaire (CPQ) prior to their dental treatment and 6 months after the treatment.
Results: Of the fifty-five patients, 40 patients (24 girls-16 boys) completed baseline and follow-up data. The mean age of the children was 11.85 (±1.02) years. The overall CPQ score ranged from 3–83 (average 33.27 ± 16.46) at baseline and 0–61 (average 11.67 ± 11.21) at follow up. The emotional well-being among children was the highest score at baseline. A significant decrease (p < 0.001) in the mean values was observed for both the overall CPQ scores and for the scores of the oral symptoms, functional limitations, and social-emotional well-being limitation. All subdomains showed large effect sizes and oral symptom limitation domain presented the greatest effect. Wilcoxon Rank test was used to determine the statistical significance of the changes and the magnitude of change was determined by calculating and classifying the effect size.
Conclusion: Restorative treatment with GH following selective caries removal positively influenced the oral health-related quality of life of children with severe molar-incisor hypomineralisation.
Key Words: Health-related quality of life, Dental enamel hypoplasia, Questionnaires, Child, Oral health.
Kur’an’da Sa‘y Kavramının Semantik Analizi
Authors: KAYA Ali
Published: June 2022

Kelimeler ve kavramlar, bulunduğu bağlama ve izafe edildiği varlığa göre farklı anlamlar ifade ettikleri gibi tarihi süreçte anlamca bazı değişimler geçirirler. Bu değişim, birçok Kur’an kelimesinin de yaşadığı bir durumdur. Farklı formlarıyla Kur’an’da otuz defa geçen sa‘y kavramı da öznesine ve bulunduğu siyaka bağlı olarak değişik manalarda kullanılmıştır. Câhiliye döneminin sosyal ve kabile hayatıyla ilgili olarak olumlu veya olumsuz muhtevayla zikredilen bu kavram, Kur’an bütünlüğünde iman/mümin, zikir ve âhiret kavramlarıyla ilişkilendirilerek olumlu (sâlih amel); fesâd, harâb ve helâk gibi kelimelerle birlikte münafıklara, Yahudilere ve müşriklere izafe edilerek olumsuz anlamda (‘amel-i seyyie) kullanılmıştır. Ayrıca birkaç âyette insan kelimesine nispet edilerek nötr olarak “mutlak amel” manasında geçmiştir. Bu çalışma, sa‘y kavramının anlam tarihine yoğunlaşmayı hedeflemektedir. Bu bağlamda öncelikle klasik lügatler yardımıyla sa‘yın temel/kök anlamı ve câhiliye şiirlerinden istifade edilerek nüzûl öncesine ait anlamları tespit edilmiştir. Akabinde bu kelimenin Kur’an bütünlüğünde ifade ettiği anlamlara değinilmiştir.
How CAAHP Cultivates Excellence in Health Professions Advising from the Heartland
Authors: Bennett Valerie A. , Kolberg Kathleen , Mecozzi Mariella , Southerland Joseph
Published: June 2022

Both CAAHP and NAAHP have deep roots in the Midwest. The Heartland is known as the breadbasket that feeds our nation. Big 10 schools and big ideas take root in our Central region as well as initiatives that feed and nourish our health professions advisor members. In CAAHP’s 50+-year history, several of those ideas, such as mentoring and providing research grants, have also become the seeds that have grown into national efforts to nourish our fellow advisors across the country. Here we have harvested a cornucopia of those initiatives of which we are most proud, and which reflect the values of CAAHP and the value we place on our members. We provide some history and discuss our current status and future directions based on our recent CAAHP strategic plan.
The color image of the traditional miniature of Uzbekistan in the professional pedagogical training system of teachers of the future fine arts
Authors: Gadoyev Ibrohim
Published: June 2022

After Uzbekistan gained its independence, special attention was paid to the important tasks of increasing the quality of education on the basis of modern requirements in faculties and departments of all higher education institutions of our country, including the organization of the system of professional training of teachers of Fine Arts on the basis of international qualification requirements. As a result of extensive reforms carried out in the field of education, efforts were made to create a national system of training future teachers of Fine Arts based on advanced foreign experiences. At the same time, important tasks related to improving the quality of professional training of future teachers of Fine Arts, improving their practical skills and professional competence in practical training are topical today. In this article, the future teachers of Fine Arts will be given ideas and comments on The Color Image of the traditional miniature of Uzbekistan in the system of professional pedagogical training.
Imom Buxoriyning “Al-adab Al-mufrad” (odob durdonalari) asarida tarbiya masalalari
Authors: Todjimamatova Mashxura
Published: June 2022

Ushbu maqolada Imom Buxoriyning “Al-adab al-mufrad” (“Adab durdonalari”) asarida ilgari surilgan tarbiya masalalari xususida so‘z boradi. Imom al-Buxoriyning odob-axloq haqidagieng sahih hadislarni o‘zida mujassam etgan ushbu asari katta tarbiyaviy ahamiyatga molik benazir to‘plamdir. Uning arabcha nashri ikki marta bosilib, 1990-yilda olim Sh. Boboxonov tomonidan asarning o‘zbekcha tarjimasi ham nashr etilgan. Al-Buxoriyning bu asarida 1322 hadis va xabarlar 644 bobda jamlangan bo‘lib, u Hindiston, Turkiya va Misrda bir necha marta chop etilgan.
Peranan Ulama Kharismatik Memotivasi Prilaku Agamis Masyarakat Kota Palembang
Authors: Yuanita Yuanita Sari
Published: June 2022

This thesis is entitled "The Role of Charismatic Ulama Motivating the Religious Behavior of Palembang City Community". The Role of Charismatic Ulama in Motivating the Religious Behavior of the Palembang City Community. ”The research method used was qualitative, with a descriptive approach. The  research focus on the great Ulama of South Sumatra Province K.H. Muhammad Zen Syukri, research subjects consisted of 4 people, namely 1 Member of the DPRD of South Sumatra Province Alfarenzi Panggarbesi, who was also assisted by Hj. Wanny Rivai as a student and adopted child of the late K.H. Zen Syukri, then Selamet, the administrator of Nurul Hidayah Mosque, and Siti who is the treasurer and administrator of the Muqimus Sunnah Islamic Boarding School which was founded by KH Zen Syukri. Data collection techniques are obtained through interview data, observation data, data documentation and literature study. Data analysis techniques, namely data reduction, display data, and conclusion verification. Based on the results of this study, it shows that the role of charismatic clerics in motivating the religious behavior of the people of Palembang City or in this case raised about the late K. H Zen Syukri as an object of research has been achieved in view of the four charismatic research indicators marked with. 1). Having great communication skills, especially in influencing the thoughts, feelings and behavior of others, thereby arousing a sense of admiration from the community towards him and easy to socialize so that other people feel sympathetic towards him. 2.) Having a calm attitude in facing everything in the face of all obstacles that occur even though you take personal risks. 3). Having a high self-confidence in doing good things.
Do Digital Payment Platforms’ Activities affect Corruption? Evidence from Panel of West African Countries
Authors: Njogo Bibiana , Mustapha S. Atanda , Obiekwe Chinelo J.
Published: June 2022

The study examines whether the digital payment platforms (ATM, POS, Mobile and Online platforms) affects the level of corruption in selected West African countries. A standard panel data models such as pooled Least Square, random effect and system GMM were adopted to generate the estimators. The findings suggest that the operation of ATM has been deterrent to corruption level in selected West African Countries. This is evidence with the negative effects observed in both the individual and interaction models. The point of sale (POS), Mobile and Online medium of electronic payments have increasing effects on corruption. This is proofed, given the positive signals seen in both the individual and interaction models. The paper further test for robustness through model re-specification and changes in estimation technique and thus, reveals that the coefficients are consistent to model re-specification and advanced estimation procedure. Hence, digital payment platforms significantly influence corruption in West African countries. The implication therefore is that, the regulatory authorities and deposit money banks should advocate for larger usage of the POS and Online digital payment platforms. Also, the use of the mobile platform should be regulated to contend with insecurity it heralds.
Pengaruh Covid-19, Tingkat Inflasi dan Harga Minyak Mentah Terhadap Keputusan Investasi di Bursa Efek Indonesia
Authors: Lutfiyah Nyimas
Published: June 2022

Macroeconomic conditions will affect the capital market and will certainly affect investors in predicting future economic changes. The purpose of this study is to determine the effect of Covid-19, inflation rates and oil prices on investment decisions on the Indonesia Stock Exchange. The sample in this study is the number of confirmed cases of Covid-19, inflation rate and oil prices for the period March 2020 - January 2022. This type of research is associative research. The data used in this study is time-series data. Methods of data collection using the method of documentation. The data analysis method used is quantitative. The data analysis technique used multiple linear regression. The results showed that (1) Covid-19 had a significant effect on stock prices and trading volume, (2) Inflation rates had no significant effect on stock prices and trading volume, (3) Crude oil prices had a significant effect on stock prices and trading volume