bluuebunny/crossref_metadata_2025 huggingface dataset:
Vesico-Vaginal Fistula Repair by a Vaginal Approach
Authors: Colenbrander Jorrit , Heesakkers John , Martens Frank
Published: September 2021

Introduction: The aim of this study is to determine the outcome of surgically treated vesico-vaginal fistulae (VVaFs) using a transvaginal approach with a Latzko technique. Methods: A retrospective chart study was conducted at the Department of Urology, Radboud University Medical Centre. Surgical approaches to repair VVaF, from 2014 to September 2020, were selected. Patients who underwent a transvaginal approach were included. The primary objective was fistula closure. Secondary objectives were predictive factors for the outcome of the surgical procedure, for example, patient characteristics, leakage on cystography 2 weeks postoperative, and surgery time. Results: Thirty-one patients had surgery for VVaF. Twenty-five procedures (81%) were performed transvaginally. Thirteen of these (52%) had successful transvaginal closure after the first attempt. Seven out of 12 had their second attempt at the time of analysis, of which 4 (57%) were successfully closed thereafter. After either 1 or 2 attempts with the transvaginal approach, 17 (68%) of the VVaFs were successfully closed, but 79% if patients who did not yet had a second attempt were taken into account with the current success extrapolated. Only few minor complications were observed. Conclusion: Transvaginal closure of VVaFs with a Latzko technique is successful in about 79% in either 1 or 2 attempts, with few minor complications. A second attempt in closing the fistula with a transvaginal approach is useful, and a previous transvaginal attempt is not a contraindication for a second transvaginal attempt in closing the VVaF surgically.
Seroprevalence, Genotyping, and Monitoring of Hepatitis C Viral Loads in Patients on Antivirals in Burkina Faso
Authors: Yelemkoure Edwige T. , Yonli Albert T. , Sombie Hermann K. , Tao Issoufou , Zouré Abdou Azaque , Ouattara Abdoul Karim , Sorgho Abel P. , Zongo Arsène W. , Zeba Moctar T.A. , Kiendrebeogo Isabelle T. , Bado Prosper , Kabré Madeleine K. , Zohoncon Théodora M. , Djigma Florencia W. , Obiri-Yeboah Dorcas , Simpore Jacques
Published: September 2021

Introduction: Hepatitis C virus (HCV) infection remains a major public health problem worldwide. In Burkina Faso, nearly 720,000 people are living with HCV, and each year about 900 people die from complications of cirrhosis or hepatocellular carcinoma. This study was planned to determine the HCV seroprevalence, characterize circulating genotypes, and monitor HCV viral loads in patients under treatment with antivirals. Methods: A total of 4,124 individuals and 167 patients in the pre-therapy program were recruited. The “SD Bioline HCV” kit was used for rapid screening of anti-HCV antibodies. Viral load and genotyping were performed in 167 HCV patients on antivirals using the “Iontek HCV Quant” and “Iontek genotyping” kits. Results: Prevalence of HCV was 1.65% (68/4,124), and the median viral load of participants was 5.37 log10/mL (1.32–7.67 log10/mL). Genotype 2 was predominant with a frequency of 86.23% (144/167) and appeared to be more active with higher viral load compared to 13.77% (23/167) for genotype 1 (p < 0.001). After 24 weeks of pan-genotypic direct-acting antivirals, such as sofosbuvir/daclatasvir and sofosbuvir/velpatasvir, the viral loads of all patients became undetectable. Conclusion: The responses to antivirals by the circulating genotypes indicate that the results are very satisfactory. Therefore, the prevalence of HCV in the population can be reduced through identification of cases and treatment.
Sobre alegorias e intervenções na (semi) periferia – alternativas à escrita histórica em campo de trânsito de João Paulo Borges Coelho e life & times of Michael k de J.M. Coetzee
Authors: Banasiak Marta Maria
Published: September 2021

Tomando como ponto de partida teórico a proposta teórica de Warwick Research Collective no presente ensaio propõe-se uma análise comparativa de Campo de Trânsito de Jõao Paulo Borges Coelho e Life & Times of Michael K, de J.M. Coetzee. A análise foca as modalidades narrativas através das quais os autores driblam entre as formas alegóricas e diretas de reflexão sobre as realidades mundiais e locais.
QT Interval Dynamics and Cardiovascular Outcomes: A Cohort Study in an Integrated Health Care Delivery System
Authors: Mantri Neha , Lu Meng , Zaroff Jonathan G. , Risch Neil , Hoffmann Thomas , Oni‐Orisan Akinyemi , Lee Catherine , Jorgenson Eric , Iribarren Carlos
Published: September 2021

Background

Long QT has been associated with ventricular dysrhythmias, cardiovascular disease (CVD) mortality, and sudden cardiac death. However, no studies to date have investigated the dynamics of within‐person QT change over time in relation to risk of incident CVD and all‐cause mortality in a real‐world setting.

Methods and Results

A cohort study among members of an integrated health care delivery system in Northern California including 61 455 people (mean age, 62 years; 60% women, 42% non‐White) with 3 or more ECGs (baseline in 2005–2009; mean±SD follow‐up time, 7.6±2.6 years). In fully adjusted models, tertile 3 versus tertile 1 of average QT corrected (using the Fridericia correction) was associated with cardiac arrest (hazard ratio [HR], 1.66), heart failure (HR, 1.62), ventricular dysrhythmias (HR, 1.56), all CVD (HR, 1.31), ischemic heart disease (HR, 1.28), total stroke (HR, 1.18), and all‐cause mortality (HR, 1.24). Tertile 3 versus tertile 2 of the QT corrected linear slope was associated with cardiac arrest (HR, 1.22), ventricular dysrhythmias (HR, 1.12), and all‐cause mortality (HR, 1.09). Tertile 3 versus tertile 1 of the QT corrected root mean squared error was associated with ventricular dysrhythmias (HR, 1.34), heart failure (HR, 1.28), all‐cause mortality (HR, 1.20), all CVD (HR, 1.14), total stroke (HR, 1.08), and ischemic heart disease (HR, 1.07).

Conclusions

Our results demonstrate improved predictive ability for CVD outcomes using longitudinal information from serial ECGs. Long‐term average QT corrected was more strongly associated with CVD outcomes than the linear slope or the root mean squared error. This new evidence is clinically relevant because ECGs are frequently used, noninvasive, and inexpensive.
High‐Resolution Mapping and Ablation of Atrial Tachycardias Involving the Lateral Left Atrium
Authors: Miyazaki Shinsuke , Hasegawa Kanae , Yamao Kazuya , Mukai Moe , Aoyama Daisetsu , Sekihara Takayuki , Nodera Minoru , Eguchi Tomoya , Iesaka Yoshito , Tada Hiroshi
Published: September 2021

Background

The lateral left atrium (LA) is often associated with atrial tachycardia (AT) because of its complex anatomy. We sought to characterize ATs associated with the lateral LA, including the posterolateral mitral isthmus (MI) and left atrial ridge.

Methods and Results

Twenty‐eight lateral LA‐associated ATs were mapped with high‐resolution mapping systems and entrainment pacing. The vein of Marshall was mapped with a 1.8‐Fr mapping catheter when possible. ATs were associated with the posterolateral MI in 18 ATs (14 perimitral, 3 small reentry, and 1 focal AT). All patients had undergone MI area ablation, and all ATs were successfully eliminated. During 27.0 (interquartile range, 10.5–40.0) months of follow‐up, all were free from any atrial tachyarrhythmias, with 3 patients on antiarrhythmics. Of 10 ATs involving the ridge or Marshall bundle, 3 were ridge related, 3 were Marshall bundle related based on vein of Marshall mapping, and 1 was a persistent left superior vena cava related AT. All 7 patients had undergone MI linear ablation. The critical isthmus was in the LA‐ridge junction or the LA‐Marshall bundle junction. Bidirectional conduction block between the LA and ridge or Marshall bundle was created. Two patients had the critical isthmus in the other area. The remaining patient had micro‐reentry in the ridge. All 10 ATs were terminated during ablation at the critical isthmus. During 12.0 (5.2–31.7) months of follow‐up, all were free from any atrial tachyarrhythmias, with 7 patients on antiarrhythmics.

Conclusions

Most ATs occurred after MI area ablation. An high resolution mapping‐guided approach is highly effective for identifying the mechanism.
Multifaceted interactions between urban humans and biodiversity-related concepts: A developing-country dataset
Authors: Nguyen Minh-Hoang
Published: September 2021

Urban humans and biodiversity-related concepts are interacting with each other in many negative and positive ways. The biodiversity provides a wide array of provision and cultural-ecological services to urban residents, but it is being overexploited to the point of crisis. The crisis is largely driven by the expanding illegal wildlife trade in developing countries with a high urbanization rate and biodiversity level like Vietnam. While supply-side measures are ineffective in reducing biodiversity loss, researchers have suggested demand-side measures as supplements, such as social marketing campaigns and law enforcement in urban areas. Moreover, urban residents are also potential visitors to urban public parks and national parks, which helps generate finance for biodiversity preservation and conservation in those places. Understanding how urban residents' perceptions towards biodiversity and biodiversity-related behaviors can help improve the effectiveness of conservation efforts and sustainable urban development. Thus, this article presents a dataset of 535 urban residents' wildlife consumption behaviors, multifaceted perceptions and interactions with biodiversity-related concepts, and nature-based recreation demand. The dataset is constructed with six major categories: 1) wildlife product consumption, 2) general biodiversity perceptions, 3) biodiversity at home and neighborhood, 4) public park visitation and motivations, 5) national park visitation and motivations, and 6) socio-demographic profiles. These resources are expected to support researchers in enriching the lax literature regarding the role of urban residents in biodiversity conservation and preservation, and help policymakers to find insights for building up an “eco-surplus culture” among urban residents through effective public communication and policymaking.
Ancient Greek I
Authors: Peek Philip S.
Published: September 2021

In this elementary textbook, Philip S. Peek draws on his twenty-five years of teaching experience to present the ancient Greek language in an imaginative and accessible way that promotes creativity, deep learning, and diversity.

The course is built on three pillars: memory, analysis, and logic. Readers memorize the top 250 most frequently occurring ancient Greek words, the essential word endings, the eight parts of speech, and the grammatical concepts they will most frequently encounter when reading authentic ancient texts. Analysis and logic exercises enable the translation and parsing of genuine ancient Greek sentences, with compelling reading selections in English and in Greek offering starting points for contemplation, debate, and reflection. A series of embedded Learning Tips help teachers and students to think in practical and imaginative ways about how they learn.

This combination of memory-based learning and concept- and skill-based learning gradually builds the confidence of the reader, teaching them how to learn by guiding them from a familiarity with the basics to proficiency in reading this beautiful language. Ancient Greek I: A 21st-Century Approach is written for high-school and university students, but is an instructive and rewarding text for anyone who wishes to learn ancient Greek.
Coupled Effects of Moisture Transport Pathway and Convection on Stable Isotopes in Precipitation across the East Asian Monsoon Region: Implications for Paleoclimate Reconstruction
Authors: Zhang Jingyi , Yu Wusheng , Jing Zhaowei , Lewis Stephen , Xu Baiqing , Ma Yaoming , Wei Feili , Luo Lun , Qu Dongmei
Published: September 2021

This study investigated the variations in stable oxygen isotopes in daily precipitation (δ18Op) collected between 2010 and 2013 at four sites across the East Asian monsoon region to address the controversy whether local meteorological factors, moisture transport pathway or convection dominates the δ18Op changes. We found that the δ18Op time series exhibit opposite seasonal patterns between the southern and northern sites; however, relatively low δ18Op values occur at each site during summer. The opposite seasonal patterns are closely related to the proportional change in the contributions from oceanic (> 52% in the south) and continental (> 85% in the north) moisture sources. Moisture transport distances also influence the seasonal δ18Op fluctuations. In the south, the moisture transported over short distances from the middle of the western Pacific Ocean results in relatively high δ18Op values during the pre-monsoon season. In contrast, long-distance transport of moisture from the Indian and Equatorial Pacific Oceans during the monsoon season results in relatively low δ18Op values. In the north, relatively low δ18Op values during the monsoon season can be attributed to an increase in relatively distant moisture originated from the middle of the western Pacific Ocean. Convection only plays a role in affecting δ18Op values in the south during the monsoon season. Our study suggests that moisture transport pathway (moisture sources and moisture transport distances) is a major factor that governs seasonal variations in δ18Op across the East Asian monsoon region, which has implications for the interpretation of paleoclimate records from this region.
Aftermath of anti-police protests in Nigeria: Burden and predictors of psychiatric morbidity among protesters and non-protesters
Authors: Ayinde Olatunde Olayinka , Atere Oluwasemiloore Peace , Ibeawuchi Ugonna , Bello Toyin , Ogunkoya Abiola , Asafa Olayinka , Abdulmalik Jibril
Published: September 2021

Objectives:

Anti-police (#EndSARS) protests took place in October 2020 across several Nigerian cities, resulting in deaths, injuries and loss of property, but the psychological sequelae of these protests have not been studied.

Method:

In a cross-sectional online survey, we collected data on psychiatric morbidity and potential risk factors from 426 Nigerian social media users, who self-identified as participants or non-participants in a recent anti-police protest.

Results:

We found elevated rates of psychiatric morbidity, with worse outcomes for protesters compared to non-protesters (psychological distress [44.2% vs 29.8%], depression [26.0% vs 14.9%], anxiety [51.0% vs 29.8%], post-traumatic stress disorder [7.4% vs 1.8%], current substance use [11.2% vs 4.5%] and suicidal ideation [7.1% vs 4.4%], respectively). After adjusting for the effects of COVID-19 pandemic and previous mental health diagnosis, the predictors of poor mental health among non-protesters were being unmarried (odds ratio = 7.4, p = 0.01) and low resilience (odds ratio range = 4.1–5.4, p < 0.03) while for the protesters, the predictors were low resilience (odds ratio range = 2.9–4.7, p < 0.01), being from Northern Nigeria (odds ratio = 4.7, p < 0.01) or residing in Northern Nigeria (odds ratio = 2.8, p = 0.03), being under-/unemployed (odds ratio range = 2.1–2.5, p < 0.04), holding the view that the protest was caused by the state of the economy (odds ratio = 2.0, p = 0.01), belief that the protest had a direct negative impact on the protester (odds ratio = 2.3, p = 0.04) and willingness to participate in future protests (odds ratio = 4.13, p = 0.02).

Conclusion:

We conclude that participating in the #EndSARS protest was associated with significant psychiatric morbidity. There is need to recognise and address the mental health sequelae of collective actions, and invest in programmes that build resilience and address socio-political determinants of mental health, especially with a focus on youth.
A Lexical Approach to Assessing Stress: Development and Proof-of-Concept
Authors: Driskell Tripp , Salas Eduardo , Burke C. Shawn , Driskell James E.
Published: September 2021

Objective

We describe a methodology that provides a nonobtrusive means of detecting stress and related deficits through the assessment of spontaneous verbal output in ongoing communications.

Background

In high-demand environments, operational personnel are exposed to an array of environmental, task, and interpersonal stressors that can negatively impact performance as well as jeopardize safety and well-being. In these settings, the requirement exists to assess cognitive and emotional state “at a distance” and without interfering with ongoing performance.

Method

We describe a lexical approach to assessing stress effects from ongoing or spontaneous verbal output. This approach is examined in a spaceflight analog setting.

Results

We assess stress effects in terms of five core dimensions and develop lexical indicators of these core stress dimensions and relevant sub-facets. We establish the proof-of-concept of this approach by presenting representative data from a spaceflight analog.

Conclusion

This approach provides an unobtrusive means to evaluate ongoing task communications at the individual and team level in order to assess cognitive/emotional states such as workload, negative affect, attentional focus, anxiety, and team orientation.

Application

There are many high-demand settings in which it is valuable to monitor the potential negative effects of stress on operational personnel. These environments include spaceflight, the military, aviation, law enforcement, and medicine.
Human insecurity and psychological well-being in migrants hosted in a Nigerian transit center: A qualitative exploration on risk and protective factors
Authors: Veronese Guido , Romaioli Diego , Pancake Rachel , Vigliaroni Marzia
Published: September 2021

Our explorative work aimed to qualitatively analyze the factors affecting human security and psychological well-being in a group of migrants temporarily hosted in a Nigerian transit center. The study involved 250 migrants from different Western and sub-Saharan African countries who were interviewed during their stay in International Organization for Migration – supported transit centers. Thematic content analysis was performed on the texts of the interviews. Motivations for departure from the home country, resources available for migrants’ sense of security, expectations for their future, experience in the host country, and the relationship between human insecurity and life satisfaction were the main emerging themes.
Rethinking the residual policy response: Lessons from Hong Kong older women’s responses to the COVID-19 pandemic
Authors: Yu Sam Wai Kam , Lo Iris Po Yee , Chau Ruby Chui Man
Published: September 2021

This article examines older women’s experiences of searching for face masks and handling mask-related issues during COVID-19. Set within the context of the Hong Kong government’s policy reaction to the shortage of masks in early 2020, the article draws on interviews with 40 older women in Hong Kong to identify their various forms of vulnerability to welfare threats and their active and diverse responses in times of crisis. The findings reveal the implications of the government’s residual policy response for people’s vulnerability to welfare threats. They also carry practical implications for the support that social workers can provide.
Dental Attendances to General Medical Practitioners in Wales: A 44 Year-Analysis
Authors: Currie C.C. , Stone S.J. , Brocklehurst P. , Slade G. , Durham J. , Pearce M.S.
Published: September 2021

One-third of the UK population is composed of problem-oriented dental attenders, seeking dental care only when they have acute dental pain or problems. Patients seek urgent dental care from a range of health care professionals, including general medical practitioners. This study aimed to identify trends in dental attendance at Welsh medical practices over a 44-y period, specifically in relation to dental policy change and factors associated with repeat attendance. A retrospective observational study was completed via the nationwide Secure Anonymised Information Linkage (SAIL) Databank of visits to general medical practice in Wales. Read codes associated with dental diagnoses were extracted for patients attending their general medical practitioner between 1974 and 2017. Data were analyzed with descriptive statistics and univariate and multivariable logistic regression. Over the 44-y period, there were 439,361 dental Read codes, accounting for 288,147 patient attendances. The overall attendance rate was 2.60 attendances per 1,000 patient-years (95% CI, 2.59 to 2.61). The attendance rate was negligible through 1987 but increased sharply to 5.0 per 1,000 patient-years in 2006 (95% CI, 4.94 to 5.09) before almost halving to 2.6 per 1,000 in 2017 (95% CI, 2.53 to 2.63) to a pattern that coincided with changes to National Health Service policies. Overall 26,312 patients were repeat attenders and were associated with living in an area classified as urban and deprived (odds ratio [OR], 1.22; 95% CI, 1.19 to 1.25; P < 0.0001) or rural (OR, 0.84; 95% CI, 0.83 to 0.85; P < 0.0001). Repeat attendance was associated with greater odds of having received an antibiotic prescription (OR, 2.53; 95% CI, 2.50 to 2.56; P < 0.0001) but lower odds of having been referred to another service (OR, 0.75; 95% CI, 0.70 to 0.81; P < 0.0001). Welsh patients’ reliance on medical care for dental problems was influenced by social deprivation and health policy. This indicates that future interventions to discourage dental attendance at medical practitioners should be targeted at those in the most deprived urban areas or rural areas. In addition, health policy may influence attendance rates positively and negatively and should be considered in the future when decisions related to policy change are made.
Exploring Managerial Attitudes Toward Various Participation Mechanisms in Response to Citizen Satisfaction Signals on Public Service Quality
Authors: Oh Youngmin , Shin Heontae , Park Jongsun
Published: September 2021

This study identifies the impacts of different citizen satisfaction signals (positive/negative) on managers’ agreement to use various participation channels. Citizen satisfaction with public service quality plays an essential role in managers’ accountability expectations. Accordingly, it is crucial to examine how public managers use participation mechanisms, reacting to citizen satisfaction signals on public service quality. The results confirm a negativity bias: Managers are more reactive to citizens’ negative signals than a positive signal in their service quality evaluations. However, the negative signal’s effect does not reach the participation tools, where the degree of their decision-making is highly delegated to citizens.
Philo of Alexandria on the Obligations of Wealth
Authors: Sterling Gregory E.
Published: September 2021

The views of Philo of Alexandria on wealth have been a source of controversy between those who argue that Philo was at times critical of wealth and those who contend that these criticisms were not of wealth but of the dangers posed by wealth. This article evaluates Philo’s position first by examining the evidence for his own wealth and then by considering two sets of texts from the Exposition of the Law: one set that interprets the biblical prohibitions against interest on loans (Spec. 2.74-78; Virt. 82-87) and another that evaluates the use of wealth (Spec. 2.16-23). The former set of texts are evaluated against the realia of Jewish loan practices in Egypt, while the second set is evaluated against Philo’s own family situation. The conclusion is that Philo was not critical of wealth per se, but of the misuse of wealth and the neglect of the poor.
Searching for a Public in Controversies over Carbon Dioxide Removal: An Issue Mapping Study on BECCS and Afforestation
Authors: Waller Laurie , Rayner Tim , Chilvers Jason
Published: September 2021

The roles digital media-technologies play in raising public issues relating to emerging technologies and their potential for engaging publics with science and policy assessments is a lively field of inquiry in Science and Technology Studies (STS). This paper presents an analysis of controversies over proposals for the large-scale removal of atmospheric carbon dioxide (CDR). The study combines a digital method (web-querying) with document analysis to map debates about two CDR approaches: bioenergy with carbon capture and storage (BECCS) and afforestation. In the first step, we locate actors using the web to engage with BECCS and afforestation and map their alignments in relation to competing framings of CDR. In a second step, we examine the devices deployed by UK-based actors to evidence and contest the feasibility of BECCS and afforestation. Our analysis shows that policy distinctions between “natural” and “engineered” CDR are used flexibly in practice and do not map neatly onto actor engagement with BECCS and afforestation. We highlight the predominance of cross-cutting techno-economic expertise and argue that framings of CDR as a solution to governing climate change may contribute to public disengagement from climate policy processes. The paper reflects on methods for studying controversies, publics, and issues emerging around processes of technoscientific assessment.
Romanian Short Version of the Burnout Assessment Tool: Psychometric Properties
Authors: Oprea Bogdan , Iliescu Dragoş , De Witte Hans
Published: September 2021

The Burnout Assessment Tool (BAT) represents a new measure of burnout that addresses the shortcomings of previous instruments. This study investigates the psychometric properties of the Romanian short version of the BAT. The sample consisted of 648 employees that completed the short version of the BAT. Of this sample, 117 employees also completed measures for other well-being indicators, job demands, job resources, personality, and organizational outcomes. According to our findings, there are strong correlations between the four core (exhaustion, emotional impairment, cognitive impairment, and mental distance) and two secondary (psychological distress and psychosomatic complaints) burnout symptoms. The scales presented appropriate reliability indicators. Results also support the convergent, discriminant, and construct validities. The Item Response Theory analysis showed a good coverage of the latent trait and the confirmatory factor analyses revealed appropriate fit indices. Theoretical and practical implications are discussed.
Performance as Social Resistance: Pussy Riot as a Feminist Avant-garde
Authors: Riccioni Ilaria , Halley Jeffrey A.
Published: September 2021

This article describes the short but remarkable sociopolitical life of the Russian rock group Pussy Riot. The group became famous in 2012 not only for the political content of its performances but for its transgressive performativity: its violation of established public settings and its creation of disturbing anti-authoritarianism images of today’s official Russia. The analysis aims to establish Pussy Riot as part of an avant-garde movement and as a radicalization of the very idea of the avant-garde against the familiarity of the public aspect of everyday life. Public ‘normalcy’ reveals itself to be complicit in that what should be criticized is instead taken for granted, and legitimized. Pussy Riot is a new art avant-garde in terms of both how it relates to activism, social justice, feminism, and art, and to the general public, not only to the art world.
Self-supervised learning for using overhead imagery as maps in outdoor range sensor localization
Authors: Tang Tim Y. , De Martini Daniele , Wu Shangzhe , Newman Paul
Published: September 2021

Traditional approaches to outdoor vehicle localization assume a reliable, prior map is available, typically built using the same sensor suite as the on-board sensors used during localization. This work makes a different assumption. It assumes that an overhead image of the workspace is available and utilizes that as a map for use for range-based sensor localization by a vehicle. Here, range-based sensors are radars and lidars. Our motivation is simple, off-the-shelf, publicly available overhead imagery such as Google satellite images can be a ubiquitous, cheap, and powerful tool for vehicle localization when a usable prior sensor map is unavailable, inconvenient, or expensive. The challenge to be addressed is that overhead images are clearly not directly comparable to data from ground range sensors because of their starkly different modalities. We present a learned metric localization method that not only handles the modality difference, but is also cheap to train, learning in a self-supervised fashion without requiring metrically accurate ground truth. By evaluating across multiple real-world datasets, we demonstrate the robustness and versatility of our method for various sensor configurations in cross-modality localization, achieving localization errors on-par with a prior supervised approach while requiring no pixel-wise aligned ground truth for supervision at training. We pay particular attention to the use of millimeter-wave radar, which, owing to its complex interaction with the scene and its immunity to weather and lighting conditions, makes for a compelling and valuable use case.
Relationships of the neutrophil–lymphocyte and CRP–albumin ratios with the duration of hospitalization and fatality in geriatric patients with COVID-19
Authors: Kalyon Semih , Gültop Fethi , Şimşek Funda , Adaş Mine
Published: September 2021

Objective

The aim of this study was to determine the associations of the neutrophil–lymphocyte ratio (NLR) and C-reactive protein (CRP)–albumin ratio (CAR) with the duration of hospital stay and fatality rate in geriatric patients with coronavirus disease 2019 (COVID-19).

Methods

Patients older than 65 years with polymerase chain reaction-positive COVID-19 were included. Neutrophil, lymphocyte, CRP, albumin, and demographic data and the duration of hospitalization were recorded.

Results

The mean length of stay was 15 days. NLR and CAR were significantly higher in patients who died than in those who survived. The cutoffs predictive of mortality were 4.02 (area under the curve [AUC] = 0.717) for NLR and 23 for CAR (AUC = 0.781). The fatality rate among patients who required inpatient treatment was 33%.

Conclusion

NLR and CAR, which can be calculated inexpensively and quickly at the first admission to the hospital, are extremely useful for estimating the duration of hospitalization and risk of mortality in geriatric patients with COVID-19. Using these data, treatment can quickly be intensified when needed.
Papillary squamous cell carcinoma successfully treated with bronchoscopic intratumoral injections of cisplatin and Endostar: a case report
Authors: Wang Yong , Li Yue , Yin Bin , Yang Xiaoping , Wang Fengchan , Wang Haiyan , Jiang Wenqing
Published: September 2021

Squamous cell carcinoma (SCC) is a malignant epithelial tumor originating from the bronchial epithelium that shows keratosis and/or intercellular bridges. Papillary squamous cell carcinoma (PSCC) is an extremely rare subtype of SCC that manifests with a unique intrabronchial papillary growth pattern. Surgical resection is still the first recommendation for localized noninvasive SCC. However, some patients are not candidates for surgical resection. With the development of interventional pulmonology, bronchoscopic interventional therapy has played a key role in the treatment of central airway tumors. Here, we report a case of noninvasive PSCC in the airway treated with an electric snare, argon plasma coagulation (APC), and cryotherapy. After removing the tumor by electrotomy, cryotherapy, and APC, the tumor was injected with Endostar 15 mg (3 ml) and cisplatin 20 mg (diluted to 3 ml with 0.9% normal saline) in six separate sites, once every 21 days. The tumor was eliminated, and the treatment was stopped after four treatment cycles. During the 1-year follow-up, there was no recurrence of PSCC in the airway. In this case, submucosal injections of Endostar combined with cisplatin was a feasible and effective endoscopic method for treating a low-grade intratracheal malignant tumor.
Mock circulatory loops used for testing cardiac assist devices: A review of computational and experimental models
Authors: Cappon Femke , Wu Tingting , Papaioannou Theodore , Du Xinli , Hsu Po-Lin , Khir Ashraf W
Published: September 2021

Heart failure is a major health risk, and with limited availability of donor organs, there is an increasing need for developing cardiac assist devices (CADs). Mock circulatory loops (MCL) are an important in-vitro test platform for CAD’s performance assessment and optimisation. The MCL is a lumped parameter model constructed out of hydraulic and mechanical components aiming to simulate the native cardiovascular system (CVS) as closely as possible. Further development merged MCLs and numerical circulatory models to improve flexibility and accuracy of the system; commonly known as hybrid MCLs. A total of 128 MCLs were identified in a literature research until 25 September 2020. It was found that the complexity of the MCLs rose over the years, recent MCLs are not only capable of mimicking the healthy and pathological conditions, but also implemented cerebral, renal and coronary circulations and autoregulatory responses. Moreover, the development of anatomical models made flow visualisation studies possible. Mechanical MCLs showed excellent controllability and repeatability, however, often the CVS was overly simplified or lacked autoregulatory responses. In numerical MCLs the CVS is represented with a higher order of lumped parameters compared to mechanical test rigs, however, complex physiological aspects are often simplified. In hybrid MCLs complex physiological aspects are implemented in the hydraulic part of the system, whilst the numerical model represents parts of the CVS that are too difficult to represent by mechanical components per se. This review aims to describe the advances, limitations and future directions of the three types of MCLs.
Environmental impact comparison of wheat straw fast pyrolysis systems with different hydrogen production processes based on life cycle assessment
Authors: Zheng Xiang , Zhong Zhaoping , Zhang Bo , Du Haoran , Wang Wei , Li Qian
Published: September 2021

This study aimed to evaluate the environmental impact of 1000 kg h−1 wheat straw to produce biofuel via fast pyrolysis with three different hydrogen production processes by the life cycle assessment (LCA) based on Chinese Life Cycle Database (CLCD). The primary energy depletion (PED), global warming potential (GWP), abiotic depletion potential (ADP) and respiratory inorganics (RI) impact categories of 1 MJ biofuel produced were employed for comparison. In case 1, the hydrogen was derived from natural gas steam reforming, and all the bio-oil was hydrotreated to produce the biofuel. In case 2, a part of the aqueous phase was reformed to produce hydrogen, whereas the remaining bio-oil was hydrotreated to produce biofuel. In case 3, all the aqueous phase of bio-oil was reformed to produce hydrogen, a part of hydrogen generated by reforming was used to oil phase hydrotreated and the excess hydrogen was considered as a co-product. Our results show that the PED, GWP, ADP and RI of case 3 are 0.1355 MJ, −17.96 g CO2eq., 0.0338 g antimonyeq and 0.0461 g PM2.5eq.. Compared with conventional diesel, the PED, GWP, ADP and RI of case 3 were reduced by 89.81, 117.44, 1.74 and 85.03%, respectively. The results of sub-process contribution analysis and sensitivity analysis suggested that the electricity consumption for the bio-oil production has the maximal effect on the total PED, GWP and RI of case 3, whereas the amount of fertilizers in the biomass production sub-process has the maximal effect on the total ADP.
Generation of infectious waste during the COVID-19 pandemic: The case of a Brazilian hospital
Authors: Martins Mariana Alves , Pataca Luiz Carlos Moutinho , Santos Elci de Souza , Faria Shirlei Moreira da Costa , Cruz Leandro Américo , Silva Glauber Augusto Simplício , Mol Marcos Paulo Gomes
Published: September 2021

Coronavirus-19 disease (COVID-19) acquired pandemic status in March 2020. The new virus has caused serious implications in the healthcare services management, including several sectors, among them the generation of waste. Healthcare wastes (HCW) generation increased along pandemic representing a health problem due to potentially infected ones. From this perspective, the study sought to analyse the challenges and changes imposed by COVID-19 in the HCW management in a large public hospital from Brazil. For this purpose, data about the Contingency Plan prepared by the hospital and HCW generation from 2017 to 2020 were used, analysed by statistical methods. When dealing with the Contingency Plan, the Brazilian hospital adopted measures similar to other hospitals around the world as described by the literature, such as: adoption of new protocols, specific team assigned to manage actions and training of professionals and suspension of elective surgeries. Regarding the generation of HCW, there was a significant increase in the mass of biological waste with a high risk of infection. The waste of this group increased from March 2020, coinciding with the start of care for the patients infected by COVID-19. The contribution of this type of waste to total generation jumped from approximately 0.2% in previous years to almost 5% in 2020. In addition, a reduction in the average of total waste generated in kilogrammes per bed per day from 2017 to 2019 was indicated compared to the 2020. COVID-19 pandemic led to major challenges for hospitals that had to care for patients infected with the SARS-CoV-2 virus, including new protocols, changing the work shifts and training the teams in the new procedures. The biological waste with a high risk of infectiousness also increased 30 times.
The Lived Experiences of Highly Mobile Military Adolescents in Search of Their Identity: An Interpretive Phenomenological Study
Authors: Thomas Jennifer S. , Smart Denise , Severtsen Billie , Haberman Mel R.
Published: September 2021

The challenges that military adolescents face, including frequent relocations, pose potential risks to their identity development. The central aim of this study is to understand the impact that frequent relocations have on the identity development of highly mobile military adolescents. Military adolescents between the ages of 16 and 18 years were interviewed. An interpretive phenomenological design was employed to inform the interview and analytic approach. An inductive approach using humanistic interpretation through Hermeneutic circles was conducted. Four overarching themes were identified, including self-perception in the world, building relationships, overwhelming emotions, and fostering healthy transitions. Several subthemes developed and gave rise to common adolescent experiences. Military adolescents facing frequent relocations experience a series of identity crises that are often masked in daily life and kept secret from peers and family. Healthy transitions require the adolescent and family to openly and repeatedly explore the impact of relocations on the inner and social life of adolescents. This study calls for future research on the military adolescent-provider relationship to explore how to better help meet the needs of this population from a health care standpoint.
Factors Affecting Cuff Extrusion of Tunneled Hemodialysis Catheters
Authors: Parvulescu Flavius , Oliver Matthew J. , Reyna Myrtha E. , Pugash Robyn , David Elizabeth
Published: September 2021

Purpose:

To identify patient and procedural factors associated with extrusion of the Dacron cuff from the subcutaneous tunnel of tunneled hemodialysis catheters (THDCs).

Materials and methods:

Single center 5-year retrospective analysis of 625 catheters in 293 adult patients. Patient data included age, gender, body mass index (BMI), and common comorbidities. Procedural details included type of procedure (new insertion vs. exchange), operator seniority, side of insertion, catheter model and presence of catheter wings skin-sutures. Complications were reported as cumulative risk over time and Cox proportional hazards model was used to evaluate risk factors for cuff extrusion (CE).

Results:

Median patient follow-up was 503 days (188,913 catheter-days) and median catheter survival 163 days. CE occurred in 23.8% of catheters, at a rate of 0.79 per 1,000 catheter-days and a median time of 64 days. It was more common than infection (14.6%) and inadequate flow (15.5%). The 1-month and 12-month risk of CE was 5.9% and 21.3% respectively. A first episode of CE was a strong predictor of future CE episodes. The only patient factor that affected the risk of CE was BMI (Hazard Ratio 2.36 for obese patients). Procedural factors that affected the risk of CE, adjusted for BMI, were catheter model, type of procedure (lower risk for new insertions) and catheter wings skin-sutures; the latter reduced the 30-day CE risk by 76% without increasing catheter-related infections.

Conclusion:

Cuff extrusion is common in long-term THDCs. The risk increases with obesity, history of previous cuff extrusion, certain catheter models and absence of wing-sutures.
Novel chitosan-poly(vinyl acetate) biomaterial suitable for additive manufacturing and bone tissue engineering applications
Authors: Fourie Jaundrie , Taute Francois , du Preez Louis , de Beer Deon
Published: September 2021

Chitosan, a biocompatible and biodegradable natural polymer, offers great promise as a biomaterial for tissue engineering applications. Chitosan scaffolds have previously been fabricated using additive manufacturing techniques, however, the use of crosslinkers, weak mechanical stability and structural resolution remain problematic. In this study Chitosan-PVAc biopolymer blends were prepared using a non-organic solvent that can prepare a three-dimensional printable biopolymer in less time than conventional methods. Prepared films were characterised using SEM, FTIR and thermogravimetric analysis. Additionally, the swelling properties, biodegradability and printability of the scaffolds were also studied. The fabricated films were biodegradable within a 3-week period and showed controllable swelling properties. Results indicated no toxicity and cells attached onto films. Additionally, hydrogels showed antibacterial activity against S. aureus, S. epidermidis and E.coli, which could potentially prevent implant related infections. Additive manufacturing simulation of PVAc composite 3% chitosan and PVAc composite 4% chitosan were able to produce a layered scaffold without using crosslinkers and therefore confirming printability. Cytocompabability were assessed using a resazurin assay and cell attachment. From these results, we concluded that the printable PVAc composite 3% chitosan and PVAc composite 4% chitosan biopolymer blends meet the requirements of a biomaterial and can potentially be used for biomedical implants.
Using Multidisciplinary Partnerships to Advance Juvenile Justice Reform: Experiences in 10 Communities
Authors: Honeycutt Todd , Sakala Leah , Zweig Janine , Hague Angus Megan , Esthappan Sino
Published: September 2021

The Annie E. Casey Foundation created its national deep-end initiative to support local jurisdictions to develop and implement practices, policies, and programs that prevent youth involved in the juvenile justice system—especially for youth of color—from being sent to out-of-home placements. This article presents findings about the role that partnerships played across 10 communities in the initiative, leveraging data collected through interviews and a web-based stakeholder survey. As part of the deep-end initiative, stakeholders developed partnerships with multiple entities, though they reported partnering with community organizations, youth, and families less than with juvenile justice agencies. Family engagement emerged broadly and consistently as a priority, but stakeholders infrequently mentioned youth engagement. Sites with more collaboration typically had stronger implementation, suggesting that successful collaboration goes hand in hand with implementing broader reform activities. Developing diverse partnerships to engage in juvenile justice reform is an achievable goal that can advance reform efforts.
A multi-objective flexible job-shop cell scheduling problem with sequence-dependent family setup times and intercellular transportation by improved NSGA-II
Authors: Han Yaoyao , Chen Xiaohui , Xu Minmin , An Youjun , Gu Fengshou , Ball Andrew D
Published: September 2021

With the development of Industry 4.0 and requirement of smart factory, cellular manufacturing system (CMS) has been widely concerned in recent years, which may leads to reducing production cost and wip inventory due to its flexibility production with groups. Intercellular transportation consumption, sequence-dependent setup times, and batch issue in CMS are taken into consideration simultaneously in this paper. Afterwards, a multi-objective flexible job-shop cell scheduling problem (FJSCP) optimization model is established to minimize makespan, total energy consumption, and total costs. Additionally, an improved non-dominated sorting genetic algorithm is adopted to solve the problem. Meanwhile, for improving local search ability, hybrid variable neighborhood (HVNS) is adopted in selection, crossover, and mutation operations to further improve algorithm performance. Finally, the validity of proposed algorithm is demonstrated by datasets of benchmark scheduling instances from literature. The statistical result illustrates that improved method has a better or an equivalent performance when compared with some heuristic algorithms with similar types of instances. Besides, it is also compared with one type scalarization method, the proposed algorithm exhibits better performance based on hypervolume analysis under different instances.
Culture’s Place in Quality of Care in a Resource-Constrained Health System: Comparison Between Three Malawi Districts
Authors: Patterson Patrick B. , Mumtaz Zubia , Chirwa Ellen , Mambulasa Janet , Kachale Fannie , Nyagero Josephat
Published: September 2021

Public health scholars describe “culture of quality” in terms of desired values, attitudes, and practices, but this literature rarely includes explicitly stated theories of culture formation. In this article, we apply Fredrik Barth’s transactional model to demonstrate how taking a theory-centered approach can help to identify what would be necessary to foster “cultures of quality” outlined in the public health literature. We draw on data from a study of the Republic of Malawi’s Performance and Quality Improvement for Reproductive Health initiative. These data were generated in 2017–2018 through a 6-month organizational ethnography in three facilities selected to represent a range of districts with differing social and economic contexts. Our analysis revealed facility-level organizational cultures in which staff valued providing care, but responded to structural constraints by normalizing divergence from quality-of-care protocols. These findings indicate that sustaining a quality-oriented organizational culture requires addressing underlying conditions that generate routine experiences and practices.