bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficacy of tofacitinib in psoriatic arthritis: literature review and case report
Authors: Gridneva G. I. , Aronova E. S.
Published: November 2023

The article presents the results of a search in the PubMed and Google Scholar databases (meta-analyses, systematic reviews, clinical trials and case studies) evaluating the treatment of PsA with tofacitinib (TOFA). The review contains the most up-to-date information about the efficacy and safety of TOFA, a drug from the group of janus kinase inhibitors (JAKi), a brief description of the mechanism of action of TOFA is given, with mention of blocked signaling intracellular pathways. The spectrum of “key” clinical manifestations of psoriatic arthritis (PsA) is described, in which the therapeutic potential of TOFA (peripheral arthritis, psoriasis, enthesitis and dactylitis) is most fully revealed. The results of the main randomized controlled trials (OPAL Broaden and OPAL Beyond), postmarketing trials, descriptive studies and clinical observations are considered, and the high efficacy of TOFA for the treatment of PsA patients who did not respond to therapy with synthetic disease-modifying drugs and/ or Tumor Necrosis Factor inhibitors (TNFi) is demonstrated. The results (and their interpretation) of studying the safety of long-term use of different doses of TOFA – 5 mg 2 times a day and 10 mg 2 times a day and retention (“survival”) are presented therapy, with an emphasis on adverse events of special interest (“large” cardiological events (MACE), oncologics, infections). The results of treatment with tofacitinib in patients with PsA according to the All-Russian register of patients are presented. The pronounced positive effect of TOFA on the parameters that are defined as “patient-reported outcome – PRO” is particularly emphasized: indicators of fatigue, self-assessment, patient’s assessment of his condition according to VAS, assessment by HAQ-DI (Health Assessment Questionnaire), SF-36 (non-specific questionnaire for quality assessment patient’s life), etc. A clinical observation is presented that demonstrates a vivid therapeutic effect on arthritis, enteritis, dactylitis, clinical signs of spondylitis, sacroiliitis, as well as the skin process in a patient with active PsA.
Rehabilitation after stroke
Authors: Pizov N. A.
Published: November 2023

Stroke  is one  of the  most  common  causes  of neurological impairment in adults.  Recovery from impairment after  a stroke is  usually  incomplete, and  approximately 50% of  patients are  left  with  disabilities,  making  them  dependent on  others. Functional  deficits after stroke are also associated with huge financial burden  on the patient,  family, and society. Worldwide, stroke  is the  leading  cause  of disability in adults, often  resulting  in impairments such as muscle  weakness,  sensory deficits, spasticity, balance  problems, decreased dexterity, communication difficulties and cognitive impairment. The increased number of stroke  survivors creates  a high  demand  for effective  and  accessible neurorehabilitation  treatments. Rehabilitation after stroke aims to reduce disability by facilitating  recovery of impairment, activity or participation. Different techniques and methods  can  be  used  in rehabilitation management. Stroke  rehabilitation requires  repetitive,  intensive,  goal-oriented therapy. Rehabilitation training  can  effectively  improve  limb functioning  in stroke  patients and  reduce  disability. The effectiveness of most interventions for the upper and lower limbs is driven by repetition and principles  of task- and context-specific motor learning. Among the important directions  of stroke rehabilitation will be to optimize  the prediction  of post-stroke outcomes, identify  more  sensitive  and  specific  recovery  biomarkers,  personalize rehabilitation measures   depending on  the  severity and nature  of the vascular accident, as well as understand and address  socio-economic barriers to the recovery process.
Acute stress-induced disorders in general practice
Authors: Pizova N. V. , Pizov A. V.
Published: November 2023

Stress defines a cluster of psychophysiological responses aimed at enabling resources to solve difficult situations, as well as restoring and maintaining homeostasis in the body. Stress is a combination of physiological, neuroendocrine, behavioural and emotional responses to new or threatening stimuli and serves as a protective adaptation of the body under physiological conditions. In accordance with the effect on the body, beneficial and negative stress is distinguished. Stress can be divided into “chronic” and “acute”. The intensity of the physiological response to a stressor is highly individual and situationally dependent. Many variables, including personal attributes, coping strategies, social support, and past experiences may modify the physiological stress response in any given situation and can account for the different response of people exposed to the same stressor. Intense and persistent stress can lead to psychological and pathological body injury. Stress has a significant impact on different brain regions, including the hippocampus, hypothalamus, amygdala etc. Depression, anxiety, cognitive deficits, and even stress-induced mental diseases are closely related to functional and structural damage of the related brain regions. Repetitive daily acute stress can be associated with different diseases, first of all cardiovascular diseases, which affect quality of life and can cut short life expectancy. Timely treatment is required to prevent progression of early stress reactions to chronic post-traumatic stress disorder, especially in individuals at high risk. Advanced stress and anxiety management interventions include non-pharmacological and pharmacological treatments.
GEOPOLITICAL CLIMATE AND WORLD SYSTEM OF THE 21ST CENTURY: DOMINANT TENDENCIES
Authors: Herasina Liudmyla
Published: November 2023

The article methodologically rethinks the heuristic ability of the classical imperatives of geopolitics in the analysis of the current international situation. A systematic streamlining of dominant trends (global, regional, temporal) in the changed geopolitical space is being carried out in terms of their scale, strength and prospects. Theoretically substantiated new definitions of phenomena – “geopolitical world order” and “geopolitical climate”, which are formed and changed as a result of the actions of the dominant trends in world politics.
POLITICAL TRANSFORMATIONS IN UKRAINE (1991-2019): RUNNING IN A CIRCLE ON THE WAY TO DEMOCRACY
Authors: Pashkov Viktor , Khomeriki Olena
Published: November 2023

The article at tempts to comprehend the transformations of the political regime in Ukraine in the period 1991-2019. The features of the political development of the country since the declaration of independence, the specifics and logic of the functioning of the political regime in Ukraine during the presidency of L. Kravchuk, L. Kuchma, V. Yushchenko, V. Yanukovych and P. Poroshenko are determined. The trajectory of political development since the declaration of independence is analyzed through the prism of transitological studies. Base don’t his, it was determined hat in this process Ukraine fell into an “institutional rut”, when the change of presidents and government teams did not lead to a consistent movement towards democracy, but rather had a pendulum effect, thereby ensuring the country’s stable stay in the “gray zone” between democracy and authoritarianism. The chain of political and regime transformations in Ukraine began with the regime of the first President L. Kravchuk, which can be characterized as unconsolidated competitive authoritarianism. It functioned in a situation of constant struggle between the centers of power for the future institutional structure of the state. Since the adoption of the Constitution in 1996, it began to evolve towards consolidation, but for a number of reasons, the political regime in Ukraine in 1996-2004 reached the level of semi-consolidated competitive authoritarianism. The period of V. Yushchenko’s presidency was marked by the transformation of the country’s political regime into an unstable electoral democracy, which, after President V. Yanukovych came to power, again regressed to the level of competitive authoritarianism: in 2010-2012 – semi-consolidated, in 2012-2013 ‑ consolidated. The Revolution of Dignity marked another breakthrough in democratization and the transition to a cartel electoral democracy. However, since mid-2016, the Poroshenko regime began to evolve into unconsolidated competitive authoritarianism.
WOMEN IN MILITARY CONFLICTS AND IN POST-WAR PEACEBUILDING: WORLD AND UKRAINIAN EXPERIENCE
Authors: Chupis Anastasiia
Published: November 2023

The article analyzes the current situation in the field of women's rights in Ukraine and in the world. The international legal basis of the issue of protection of women's rights in conditions of war has been studied. The role of women is analyzed in terms of three role models according to the degree of involvement in the military conflict, namely: victim, military serviceman, women peace-builders. The topic of gender-based violence as a tool of war and terror of the civilian population, as well as mechanisms of legal protection for victims of war crimes, is revealed. The need to involve women in the processes of peace-making conflict settlements and peace-building is substantiated.
METHODOLOGICAL FOUNDATIONS OF THE POLITICAL PROBLEMS OF THE TRADITIONALIST DOCTRINE OF R. GUÉNON
Authors: Malkina Hanna , Pastukhov Anton
Published: November 2023

This scientific work explains the basic methodological determinants of political issues in the teachings of the famous French traditionalist Rene Guénon. The main scientific problem that was solved in the article is the theoretical preparation of the methodological structure of the ideas of R. Guénon and the identification of central ideas for the analysis of the political topic of the doctrine of traditionalism.
THE ROLE OF CIVILIZATION-VALUE NARRATIVES IN GLOBAL INFORMATION WARFARE
Authors: Kalynovskyi Yurii , Zhdanenko Svitlana
Published: November 2023

The prerequisites and primary indications of global information confrontation have been defined. The nature and functional characteristics of civilization-value narratives in the context of global information struggle have been analysed. The multilevel nature of information confrontation, as the interrelation between global, regional, and national levels, has been revealed. The features of civilization-value narratives in relation to specific forms of manifestation in global information warfare have been determined. The role of civilization-value narratives in the Russian-Ukrainian war has been investigated.
WORLD POWER CENTERS IN CENTRAL ASIA AND THEIR INFLUENCE ON TURKEY'S FOREIGN STRATEGY IN THE REGION
Authors: Soloviova Elnara
Published: November 2023

With the collapse of the Soviet Union, the rivalry between China, the USA, Russia, and Turkey began in Central Asia. The interests of the states and the interests of Turkey in the region are analyzed in relation to the strategy of other players. The impact of the war in Ukraine on the configuration and distribution of influence in the region is revealed. The rivalry is aimed at strengthening power and maintaining the energy resources of Central Asia.
Thermal conductivity of porous building materials: An exploration of new challenges in fractal modelling solutions
Authors: Pia Giorgio , Cappai Marta
Published: November 2023

The improvement in the insulation material performance is one of the recent crucial problems. The energy consumption in the construction and buildings field has a significant impact on the society and the environment. For these reasons, researchers have focused on studying their thermal behaviour in order to improve fabrication methods and material design structures. In this sense, a great contribution has been offered by the modeling procedures. A remarkable attention has been dedicated to the application of fractal geometry which seems to be a promising method to replicate the porous structures as well as to predict the effective thermal conductivity. In this paper, a review of different modeling procedures is presented, comparing both traditional and fractal theory-based approaches. Fractal models demonstrate high reliability in reproducing experimental data under various conditions, including dry and moist systems. This is further enhanced by the application of recursive formulas, which streamline calculations even for complex porous microstructures. The choice between one model and another depends on the specific characteristics of the materials under study. In all cases, the versatility of the analytical procedures enables one to achieve a remarkable agreement with experimental data.
A Brief, Digital Music-Based Mindfulness Intervention for Black Americans With Elevated Race-Based Anxiety and Little-to-No Meditation Experience (“healing attempt"): Replication and Extension Study
Authors: Jones Grant , Castro-Ramirez Franchesca , Al-Suwaidi Maha , McGuire Taylor , Herrmann Felipe
Published: November 2023

Background

Race-based anxiety is a critical health issue within the Black community. Mindfulness interventions hold promise for treating race-based anxiety in Black Americans; however, there are many barriers that prevent Black Americans from using these treatments, such as low cultural relevance, significant time burdens, and excessive costs.

Objective

This study is a replication and extension of findings that “healing attempt”—a brief (<60-minute), digital, music-based mindfulness intervention—is a feasible and acceptable intervention for race-based anxiety in Black Americans. In this study, we tested this research question among those with little-to-no meditation experience.

Methods

The participants were 4 Black American adults with elevated race-based trait anxiety and little-to-no meditation experience. We used a series of multiple-baseline single-case experiments and conducted study visits on Zoom (Zoom Video Communications) to assess whether the intervention can decrease state anxiety and increase mindfulness and self-compassion in Black Americans. We also assessed feasibility and acceptability using quantitative and qualitative scales.

Results

In line with our hypotheses, “healing attempt” increased mindfulness/self-compassion (Tau-U range: 0.57-0.86; P<.001) and decreased state anxiety (Tau-U range: –0.93 to –0.66; P<.001), with high feasibility and acceptability (the average likelihood of recommending “healing attempt” was 88 out of 100).

Conclusions

“healing attempt” may represent a feasible intervention for race-based anxiety in Black Americans with elevated race-based anxiety and little or no mindfulness experience. Future between-subjects randomized feasibility trials can assess whether the intervention can give rise to lasting improvements in race-based anxiety, mindfulness, and self-compassion.

Trial Registration

OSF Registries osf.io/k5m93; https://osf.io/k5m93
Perspectives of physicians treating lung cancer patients on the clinical use of outcomes: A qualitative study (Preprint)
Authors: Garcìa Abejas Abel , Marques Gomes João , Andrade María Eduarda , Canelas Daniel , Sobral María Ana , Leite costa Fabio , Salvador Verges Àngels
Published: November 2023

BACKGROUND

Using patient-reported outcome measures (PROMs) in scales can help personalize patient care pathways, including the frequency and type of clinical review. This study aims to elucidate the perceptions of physicians treating lung cancer patients regarding outcomes through questionnaires and establish relationships related to the patient, their social and family environment, with diagnosis and treatment. We also set out to identify barriers and facilitators to using these outcome measures.

OBJECTIVE

Our primary objective was to gain insight into physicians' perceptions of outcomes in treating lung cancer patients, their impact on quality of life, and how their dignity is respected. We explore the results described by doctors of the different needs and experiences of people with lung cancer in other dimensions. We also decided while identifying barriers and facilitators to using these outcome measures.

METHODS

We conducted 16 semi-structured interviews via videoconferencing with health professionals, focusing on their expert opinions on the perceived importance of their patients' outcomes and the most relevant risk variables. To this end, we conducted a qualitative thematic analysis was performed.

RESULTS

The primary groups identified in the interview analysis were patient-related, social, and family environment, and diagnosis and treatment. Some found a difference between physicians' perception of outcomes and the experiences of patients and caregivers.

CONCLUSIONS

PROMs should be implemented in daily clinical care routines. Digitalization of PROMs can facilitate their use. Barriers and facilitators are viewed as methodological divisions, influenced by factors like health literacy, digital literacy, and socioeconomic level. The relevance of PROMs lies in the feedback and subsequent management of outcomes with patients. It is a unique tool to improve the patient's spiritual needs, quality of life, and dignity. Doctors are focused on clinical Outcomes.

CLINICALTRIAL
A legal perspective on child support obligation after divorce: The Vietnamese case
Authors: Thi My Nguyen Linh , Thi Truc Huynh Giang , Khac Tran Qui
Published: November 2023

Parents are legally obligated to pay child support; if they do not live with their child Upon divorce. The obligation to support the child following a divorce is a central provision of Viet Nam's 2014 Marriage and Family Act and a significant aspect of family law. It is the responsibility of both parents and the government to safeguard children. However, the 2014 Act on Marriage and Family still needs to improve its provisions regarding child support obligations, such as the absence of a minimum quantity and a starting date. This article investigates the historical periods and regulations governing child support obligations in Viet Nam compared to other nations. This study also evaluates the practical applicability of the current legal provisions and identifies their deficiencies. This study intends to recommend modifications to child support laws that will help protect children's rights following parental divorce.
Praktik Komodifikasi dan Kepelikan Sistem dalam Shopee Affiliates Program
Authors: Fitriani Hikmatul Arifah
Published: November 2023

Technological developments bring us to live an easy life. This not only disrupts human activities in the field of technology but also spreads to various other fields such as economics, politics, and social affairs. Many things that once seemed impossible, have become possible. One example is work activities which are now becoming more practical. We no longer need to go to work every day. Now work can be done from anywhere. In a work activity, we exchange the value which we have with the wages of the industry. As with work in general, the bigger value and the work effort we give will be proportional to the wages we get. So what if there is a job offer that pays well, but requires little effort? This is what is offered by Shopee Affiliates Program. We only need to recommend products by sharing affiliate links. When someone is shopping with the link then we will get a commission income. Sounds easy and quite tempting, right? This research will analyze commodification practices in Shopee Affiliates Program and how the efforts made by Shopee to control Affiliates Partner as a third party also contribute to profits for the marketplace.
Proses Media Relations pada Holding Pangan BUMN ID FOOD
Authors: Putri Elisabeth Mirza Giesella , Rahmi Fathiya Nur
Published: November 2023

This study describes the process of media relations at the Holding Company of FOOD SOE ID FOOD. Judging from the media monitoring scoring award assessed by the Ministry of SOEs, ID FOOD was ranked first for the fertilizer and food cluster in November 2022. ID FOOD also set a target for media monitoring scoring, namely to be ranked first or second in the fertilizer and food cluster. As a Holding company of food SOE, ID FOOD has a lot of publicity which is evident from ID FOOD's scoring position, which is in first and second place. This study aims to determine the media relations process carried out by the Holding Company of FOOD SOE ID FOOD to obtain publicity in the period January 2022 - January 2023. The research method used is descriptive qualitative, using interview data collection techniques. This research shows the results that ID FOOD carries out media relations activities such as the distribution of press releases, personal approaches to the media, as well as media visits which are carried out in order to maintain good relations between the media and the company. Process media relations, from planning to evaluation, has been carried out by ID FOOD, to get publicity about the company's performance in external media.
The Personal Became Political: A Social Media Analysis of Princess Mako of Japan and Her Controversial Engagement
Authors: Okura Masako
Published: November 2023

This is a netnographical study of tweets about Princess Mako of Japan, who married in 2021 without any fanfare—no official engagement, no wedding ceremony, no wedding reception, and no dowry, thus defying convention. Her parents opposed her marriage to a controversial figure, and public opinion was largely against her. Her engagement was meant to mark a personal milestone; yet, it quickly developed into a national political controversy, ultimately questioning the raison d'être of the constitutional monarchy. The personal became political. Traditional media, as well as social media relentlessly criticized her choice, pushing her deep into Post-Traumatic Stress Disorder (PTSD). This study aims to decode covert messages embedded in the negative tweets directed at her to uncover the sentiments Twitter users knowingly or unknowingly propagated.
Curriculum Reform and Practice Exploration of "Foundation of Innovation and Entrepreneurship" for College Normal Majors
Authors: Zhou Dongsheng , Lu Yang , Wei Min
Published: November 2023

According to the statistics of the Ministry of Education, the scale of ordinary college graduates in 2023 is expected to reach 11.58 million, an increase of 820,000 compared with 2022 (General Office of the State Council of China, 2015). This figure once again hit a record high in employment, and the employment situation is becoming more and more severe. All walks of life in society have higher and higher expectations for the comprehensive ability of college students, and college students are facing greater pressure and challenges in the process of job-hunting. This paper will discuss the curriculum design, teaching mode, education and teaching reform strategy, experimental research, conclusions and prospects, so as to provide some useful references for the education and teaching reform of innovation and entrepreneurship management courses for college students, and improve the quality of graduate training and employment competitiveness.
Analysis of Translation Errors in English-Chinese Translation Practice
Authors: Zou Xing , Bai Yangming
Published: November 2023

This paper adopts the error score method to study the English-Chinese translation quality of MTI English translation majors from five dimensions: fidelity, fluency, terminology translation, style and cultural acceptance, taking the Chinese translation practice texts of students majoring in MTI English translation as the research object. The results show that students are more likely to make mistakes in terms of fluency and terminology when translating from Chinese to English, and students have difficulties in conveying the style of the original text when translating from Chinese to English. The results propose some methods of avoiding translation errors and improving the quality of translation teaching.
Semi-Analytical Modeling of Fractured Horizontal Wells in Heterogeneous Formations Considering the Interference between Hydraulic Fractures
Authors: Zhou Fangdong , Yu Yanwen , Cao Pinlu , Jiang Liangliang , Yao Shanshan
Published: November 2023

In this study, a semi-analytical model is developed for the pressure and rate transient analysis of multi-stage fractured horizontal wells. This model simulates the fluid flow towards a fractured horizontal well centered in an unconventional formation with considering the interferences between hydraulic fractures under various heterogeneity conditions. In this proposed model, the formation is divided into sub-systems, and each sub-system is further composed of linear flow regions. Boundaries of the linear flow regions are being updated in real-time response to the interferences between hydraulic fractures. Applicability of the proposed model in heterogeneous reservoirs is demonstrated by the comparison with the five-region model published in literature. The proposed model is applicable to the heterogeneity conditions including a fractured horizontal well having heterogeneous completions and/or the formation being heterogeneous in reservoir properties. Furthermore, the proposed model is utilized to analyze field data from fractured horizontal wells in heterogeneous conditions.
Применение жидкостной хроматографии со свободной неподвижной фазой в аналитической лаборатории
Authors: Марютина Т.А. , Савонина Е.Ю. , Колесниченко И.Н.
Published: November 2023

Обзор посвящен особенностям метода жидкостной хроматографии со свободной
неподвижной фазой (ЖХСНФ) и его возможностям в области выделения,
концентрирования и разделения веществ (органических и неорганических) для
решения аналитических задач. Показано, что метод ЖХСНФ может быть использован
при анализе разнообразных объектов (сверхчистые вещества, геологические
образцы, нефти, растительное сырье, фармпрепараты, почвы и др.). Отмечена
уникальная особенность метода – возможность создания градиента концентрации
реагента в неподвижной фазе в ходе хроматографического процесса.
ПРОЕКТИРОВАНИЕ МОНОЛИТНЫХ СВЧ-УСИЛИТЕЛЕЙ F-КЛАССА
Authors: Дудинов К. , Заднепряная Н.
Published: November 2023

Рассматривается подход к проектированию монолитных СВЧ-усилителей
F -класса в Х-диапазоне на основе технологического процесса PHEMT
на GaAs с нормой 0,25 мкм.
РЕЗУЛЬТАТЫ САМОКОМПЕНСАЦИИ КРУГЛОМЕРА MAHRFORM MMQ200
Authors: Епифанцев К.
Published: November 2023

В процессе калибровки измерительных приборов у производителей и у центров стандартизации и метрологии возникает необходимость расширения эталонной базы с целью более точного определения погрешности прибора. В статье рассмотрен вопрос создания эталона осевого биения для кругломера.
МАГНИТНЫЕ КОМПОНЕНТЫ КОМПАНИИ SHINHOM
Authors: Соколов М.
Published: November 2023

Shaanxi Shinhom Enterprise – одно из ключевых предприятий
по производству магнитных материалов и компонентов в Китае.
В ассортимент продукции входят ферритовые сердечники, дроссели,
катушки индуктивности, трансформаторы, фильтры электромагнитных
помех, датчики тока и другие изделия. За 35 лет своей деятельности
компания разработала более 200 серий магнитных компонентов,
которые экспортируются сегодня в 40 стран мира. Продукты компании
отличаются высоким качеством при среднем уровне цен, они с успехом
применяются в автомобилестроении, промышленности, компьютерах
и серверах, мобильных устройствах, медицинском, коммуникационном,
измерительном, навигационном оборудовании, а также системах
специального назначения. В статье представлен обзор основных
продуктовых линеек магнитных компонентов компании Shinhom.
ОТЕЧЕСТВЕННЫЕ СВИНЦОВО-­КИСЛОТНЫЕ АКБ ДЛЯ ИНФРАСТРУКТУРЫ СВЯЗИ И ЭЛЕКТРОЭНЕРГЕТИКИ
Authors: Емельяненко С.
Published: November 2023

АО «Новосибирский завод радиодеталей «Оксид» (входит в холдинг
«Росэлектроника» Госкорпорации «Ростех») – одно из ведущих предприятий
электронной промышленности по серийному производству навесных
и SMD-конденсаторов, толсто- и тонкопленочных SMD-резисторов, а также
никель-металлгидридных
аккумуляторов. Высокое качество изделий
(в том числе с приемкой «ОС») подтверждается безотказной длительной
эксплуатацией в аппаратуре авиационного, космического и специального
назначения. Система менеджмента качества компании сертифицирована
по ГОСТ Р ИСО 9001 и ГОСТ РВ 0015 в области разработки и производства
продукции двойного
и народнохозяйственного назначения. Недавно
в АО «НЗР «Оксид» была завершена работа по подготовке производства
нового для предприятия вида продукции – свинцово-кислотных
аккумуляторных батарей.
Ultrasonic Sensor-Enabled Smart Gloves for Blind Navigation
Authors: Jadhav Balasaheb
Published: November 2023

Abstract: Ultrasonic sensor-enabled smart gloves present a promising assistive technology solution for visually impaired individuals to navigate their surroundings. These gloves are equipped with an ultrasonic sensor, which utilizes sound waves to detect objects and obstacles in the environment. The sensor emits ultrasonic pulses and measures the time it takes for the waves to bounce back, providing valuable distance information. Through this real-time feedback, blind individuals can perceive their immediate surroundings and make informed navigation decisions. The integration of the ultrasonic sensor in smart gloves offers a cost-effective and efficient solution for enhancing the mobility and independence of visually impaired individuals, enabling them to navigate with greater confidence and safety.
Robotic Arm using Arduino Uno
Authors: Kulkarni Atharva
Published: November 2023

Abstract: As technology and innovation continue to improve, the development of human-like systems and methods is becoming more involved in business to meet the needs of people at a rapid pace. Such revolutions are carried out with the desire to simplify the people. This paper focuses on the development of an electro-mechanical robotic arm that attempts to pick and place and is operated or controlled through a mobile phone application via an Android smartphone. An electro-mechanical robotic arm designed to simulate pre-determined commands can typically move in four directions; left, up, down and right control in the angle defined by six servo motors and loaded with practical mobile phone features. Control of the designed and implemented robot arm is carried out using a mobile phone application through a Bluetooth module programmed through an Arduino UNO controller.
Mioclonías positivas y negativas en paciente con enfermedad renal crónica
Authors: Salgado-Montiel Luis , Ríos-Ozuna Jhonnys , Cabrales-Juan José , Franco-Dáger Edwing
Published: November 2023

Introducción: las mioclonías son contracciones musculares paroxísticas de corta duración o pérdida abrupta del tono muscular, denominadas mioclonías positivas y negativas, respectivamente. Se presenta un caso clínico de mioclonías positivas y negativas generalizadas y se pretende describir los múltiples mecanismos fisiopatológicos y etiologías que lo desencadenan.
Presentación del caso: hombre de 35 años, con diabetes mellitus tipo 1 complicada con enfermedad renal diabética en hemodiálisis, desarrolló una bacteriemia asociada a catéter por Staphylococcus aureus y presentó mioclonías positivas y negativas. Se identificaron como posibles desencadenantes la uremia, la infección y los fármacos con potencial promioclónico; el hallazgo incidental de una lesión isquémica en núcleo caudado no explicaba la semiología encontrada en el paciente. Se hizo el control y retiro de todos los factores promioclónicos enunciados, junto a manejo farmacológico con levetiracetam, y con ello se logró el control de los síntomas.
Discusión: los pacientes con enfermedad renal crónica son susceptibles a la acumulación de productos tóxicos de tipo guanidinas, que tienen potencial para producir mioclonías. Además, las infecciones, el uso de fármacos con potencial promioclónico y lesiones estructurales como las isquemias corticales son etiologías que deben considerarse en el diagnóstico diferencial. El mayor impacto en los síntomas se observa con el control del factor desencadenante, y, en caso de persistir, la terapia farmacológica proporciona buenos resultados.
Conclusión: las mioclonías son trastornos del movimiento relativamente comunes en la enfermedad renal crónica. La identificación del desencadenante es crucial para su manejo junto al uso de fármacos con actividad antimioclónica.
The Textological Analysis of the Qur’anic Manuscript Written by Syekh Muhammad Said Ranah Kumpai Kampar Riau
Authors: Putra Afriadi , Yasir Muhammad , Husin Nixson , Akram Naufal
Published: November 2023

This article examines a manuscript of the Qur'anic mushaf inherited from Sheikh Muhammad Said Ranah Kumpai (1885), from Riau, written around 1850. This article focuses on two aspects, namely, describing the type of writing and reading used in the manuscript and then comparing it with the writing and reading of other manuscripts that were contemporary with it or with the current Indonesian Standard Mushaf. Using a philological approach, this study shows that the manuscripts of Sheikh Muhammad Said were written using a mixed rasm between Usmani and Imlai. One of the factors is because the habits of the people of the archipelago at that time were stronger with oral traditions. On the other hand, the use of Usmani rasm in the Mushaf has not been a deep concern in copying the Mushaf. The qiraat used is the qiraat of Imam 'Ashim from narration of Hafs, although there are some marginal notes on certain words that can be read with other readings.
E-Commerce and Its Role during the COVID-19 Pandemic in Indonesia
Authors: Sawada Yasuyuki , Elhan-Kayalar Yesim , Shum Matthew , Yi Xu Daniel
Published: November 2023

This paper analyzes how e-commerce dynamics unfolded during the coronavirus disease (COVID-19) pandemic, using a unique, composite dataset focusing on GoFood merchants on the Gojek Indonesia platform. It expands the analysis of the platform efficiency contributions into static efficiency and dynamic efficiency perspectives. There are three key findings: online platforms like Gojek offered a novel form of social safety nets for micro, small, and medium-sized enterprises; as the COVID-19 pandemic intensified, market congestion externalities and cannibalization tendencies emerged; and women- and men-owned businesses opted for different crisis-mitigation and coping strategies. This study also demonstrates that the rapid acceleration of digital transformation presents unique research opportunities on distributive justice, external effects, and scale economies.
Anticancer acitivity of Schiff base ligand(E)-4-((5-chloro-2 hydroxybenzylidene) amino)-1, 5-dimethyl-2-phenyl-1H-pyrazol-3(2H)- one and its Co(II), Cu(II) and Zn(II) metal complexes
Authors: Sakhare Kuldeep , Sarwade Kirti , Bharate Yogesh , Sakhare Mahadeo
Published: November 2023

A series of transition metal complexes of Mn(II),Co(II), Ni(II), Cu(II), Zn(II) and VO(II) have been prepared by using the Schiff base ligand (L) derived from 4-aminoantipyrine and 5-chlorosalicylaldehyde. The structural properties of Schiff base ligand were characterized by mass, FT-IR, UV? ?Vis, 1H-NMR spectroscopy, etc. Also, metal complexes were studied by P- -XRD, elemental analysis, thermogravimetric studies along with various biological activities. The micro analytical data revealed that, the metal complexes have 1:1 stoichiometry composition of M:L. Generally, it is observed that prepared metal complexes show better antifungal, antibacterial and anticancer activities than its Schiff base ligand.
Cyber harassment of children with special reference to digital games
Authors: Baltezarevic Vesna , Baltezarevic Radoslav , Baltezarevic Ivana
Published: November 2023

Children in the modern environment are increasingly becoming active users of
digital technologies. In a digital environment, they communicate with their
peers, watch video content or have fun playing digital games. However, their
inexperience can often expose them to malicious activities from other
Internet users, such as cyber-harassment. Cyberbullies can be individuals or
groups that use audio and/ or visual content to single out a child as a
target for abusive and harassing behaviour (for various reasons). Such
activities can have long-term consequences for children (anxiety,
depression, low self-esteem, suicidal thoughts), especially if they last for
a long period of time, and if the children do not see a way out of such a
situation. Parents have certainly been identified as the first line of
defence against cyberbullying. By talking about children?s digital
activities, playing digital games together, and constantly monitoring
children?s behaviour in the digital environment, it is possible to detect
the problem in time and protect children?s digital safety. Also, companies
that produce digital games, with the development of adequate software, and
initiatives that punish the disturbing behaviour of cyber bullies, but also
praise the fair and sporting behaviour of other users, contribute to
suppressing such phenomena. The subject of this article refers to the
analysis, identification and prevention of cyber harassment to which
children are exposed in the virtual environment, especially while
interacting with other players in the process of playing digital games. The
aim of the paper is to point out the problem of cyber harassment of children
and to let the general public know that more attention must be paid to this
problem.
Advanced Oxidative Process for Treatment of Effluents with Hydroquinone in a Batch Reactor: Optimization/Modelling Technique by Response Surface Methodology and Artificial Neural Networks
Authors: YB Brandao
Published: November 2023

The main objective of this research was to evaluate by using the advanced oxidative process (AOP), a toxic compound, such as an initial hydroquinone concentration (C0) of 500 mg L-1 in a batch reactor. At this stage of the work, an optimization method was performed to obtain mineralization of the total organic carbon (TOC). Furthermore, hydrogen peroxide was used as a source of free hydroxyl radicals (•OH). First, a factorial planning 22 was carried out with the two most significant variables, and two levels were used for the variables (pH and RH). Second, a rotational central composite design (RCCD) was used to investigate the optimal point corresponding to the maximum mineralization of hydroquinone (HQ) and the variables used in the model were pH and RH. Third, the optimal point of HQ mineralization was obtained carried for the desirability function, ranging from 0.0 (very undesirable) to 1.0 (very desirable). Fourth, artificial neural networks (ANNs) was used and the values included in the experiment were time (t), initial hydrogen potential (pH), temperature of the liquid effluent (T), air flow supply (QAF), and the mole ratio of hydroquinone/hydrogen peroxide (RH). The optimal conditions for a TOC conversion, (>80%) were identified. Modeling using artificial neural networks (ANNs) was used to predict the TOC conversion as a function of time. The values of the correlation coefficients (R2) for agreement between the ANN predictions and the experimental results were approximately 0.97, indicating that the model was satisfactory. These techniques have shown to be very promising in the prediction of the degradation and mineralization of contaminants. Thus, the process modeling data by ANN, allowed to carry out a treatment of organic liquid effluents in vertical reactors installed on offshore platforms and then to release this treated water into the oceans, after the complete degradation of hydroquinone and the highest TOC conversion. Therefore, seas pollution caused by the exploration on offshore platforms of oil and natural gas, the main sources of obtaining energy in the planet, tends to be minimized, providing a more sustainable energy generation.
Targeting Goal Synergies and Transnational Partnerships for Petro-Energy Sustainability in Africa
Authors: OL Ejenavi
Published: November 2023

Sustainability goals integration in a petro-context could be considered irreconcilable. Harnessing SD goal synergies in the African petroleum sector may even be supremely problematic. Africa still grapples with a knotty mix of convoluted challenges, ranging from poverty, insecurity, drought, to extreme underdevelopment. Having contributed the least to the global climate dilemma, Africa still must bear the brunt of negative climate impacts, whilst shouldering its daunting chunk of climate adaptation and mitigation commitments. Moreover, a huge dependency on fuel imports, escalating debt profile and funding shortfalls, plague many countries at the subregional levels. In a relentless chronicle of woes, the region exhibits the highest energy deficiencies whilst contending with excruciatingly prohibitive petroleum importation costs soaring over $100 Billion USD annually. Similarly, Africa’s annual investment projections for energy are an estimated $190 billion USD. The implication is that, whereas the region has to achieve SD target obligations, its most credible means of optimising goal synergies, should be via an approach that targets energy sustainability, which remains an indispensable driver of most sustainability goals. To achieve this aim, a continental prioritization of regional partnerships is advocated to engender a sustainable petroleum sector. This is deemed crucial because of the considerable benefits the sector wields towards SDGs actualization and its relevance as a viable connector and pivot towards cleaner energy transition.
Peculiarities of the Provision of Surgical Care for Abdominal Emergencies in Hospitals Remodeled to Provide Medical Care to Patients with COVID-19 From the Perspective of a Systematic Review and Analysis of the Quality of Publications
Authors: Karsanov A. M. , Aleksandrov V. V. , Maskin S. S. , Korovin A. Ya. , Popandopulo K. I.
Published: November 2023

Relevance. Due to the pandemic of the new coronavirus infection, changes have occurred in the work of most surgical hospitals aimed at optimizing and improving the provision of medical care. Performing acute and emergency surgical interventions in patients with confirmed COVID-19 infection dictates the need to review surgical tactics.

Aim of study. To assess the quality of publications in the scientific press from the standpoint of systematic analysis on the provision of emergency surgical care in remodeled hospitals and to identify the main changes in surgical tactics in patients with abdominal emergency and COVID-19.

Material and Methods. The analysis of data from publications dated from December 2019 to July 10, 2021 from electronic databases PubMed, Cochrane Library, Scopus, eLibrary. An analysis of numerous studies, recommendations of national and international surgical, urological, oncological, gynecological, endoscopic and anesthesiological communities and associations, the World Health Organization, temporary guidelines of the Ministry of Health of the Russian Federation on the prevention, diagnosis and treatment of new coronavirus infection was performed. The quality of the selected publications was assessed in accordance with the recommendations.

Results. When analyzing the selected publications, it was revealed that most of them are retrospective, uncontrolled one-time studies and descriptions of clinical cases (level 4 evidence, level C recommendation). We found 1 combined (prospective-retrospective) multicenter and 1 retrospective comparative study on the treatment tactics of acute cholecystitis, 1 retrospective multicenter cohort study on acute pancreatitis, 1 retrospective study on acute intestinal obstruction and 2 studies on acute appendicitis, 1 case-control study on gastrointestinal tract and intestinal bleeding (level 3 evidence, level B recommendation).

Conclusion. Currently, there are no high-level evidence or recommendations to change surgical tactics in patients with COVID-19 and abdominal emergency.
Surgical Treatment of Posterolateral Rotational Instability of the Elbow: a Systematic Review
Authors: Haj Hmaidi M. A. , Lazko F. L. , Prizov A. P. , Zagorodniy N. V. , Belyak E. A. , Lazko M. F. , Nechayev V. A.
Published: November 2023

Posterolateral rotational instability (PLRI) of the elbow joint can occur acutely as a result of dislocation of the bones of the forearm, and also be chronic, for example, after inadequate healing of a previous rupture of the lateral ligamentous complex, in particular the lateral ulnar collateral ligament (LUCL). It is necessary to take into account that, as a result of repeated microtraumas, persistent pain syndrome and recurrence of dislocation develop, which can lead to disability. We conducted a systematic review of the literature according to the protocol outlined in the PRISMA guidelines. From 1,903 publications, 11 studies were selected that met our criteria and assessed the results of treatment of 181 patients. The main reason for the development of PLRI was simple traumatic dislocation of the forearm bones (37.5%). Of the studies that assessed the elbow joint using the MEPS, 86.5% of patients had excellent or good results, with a mean MEBS score of 91 points. Before surgery, pain syndrome was present in 131 patients (87.3%) out of 150, and in the postoperative period it was observed in 55 (36.6%) out of 150 (p=0.01). The incidence of recurrent instability after surgery was observed in 6.6% of patients. A review of the literature on the problem of the elbow joint shows that this problem has not been fully studied, treatment strategies differ and should be performed based on the surgeon’s experience and available data, however, it has been proven that the key to the stability of the elbow joint is the LUCL, which requires its restoration through its refixation or plastic surgery.
The Role of Extracorporeal Membrane Oxygenation in the Complex Treatment of Acute Chemical Poisoning
Authors: Simonova A. Yu. , Potskhveriya M. M. , Zhuravel S. V. , Petrikov S. S. , Talyzin A. M.
Published: November 2023

Aim of study. Analysis of literature data on the use of extracorporeal membrane oxygenation in acute chemical poisoning.

Material and methods. The search for domestic publications was carried out in the Elibrary database, foreign publications — in the MEDLINE / PubMed, Google Scholar databases for the period of 2010–2023. The terms used as a search query were according to the official MeSH terms: “Extracorporeal Membrane Oxygenation” OR “Membrane Oxygenation, Extracorporeal” OR “ECMO Treatment” AND “poisoning”.

Results. This review provides information on the outcomes of the use of veno-arterial and veno-venous extracorporeal membrane oxygenation (ECMO) for refractory cardiogenic shock, cardiac arrest and severe ARDS in acute chemical poisoning.

Conclusion. Data analysis showed that in patients with acute chemical poisoning, the incidence of complications and mortality was lower when ECMO/ECMOCPR was included in the complex therapy compared with patients in whom other reasons (not related to acute poisoning) served as indications for the use of this technique. This is probably due to the fact that patients in the group with acute poisoning are younger, they have fewer concomitant diseases; and ECMO is required, as a rule, for a shorter period of time before the toxicant is eliminated from the body using the methods of their elimination and restoration of disturbed functions.
Gastrointestinal Bleeding in Patients With New Coronavirus Infection COVID-19
Authors: Anosov V. D. , Domrachev S. A. , Ovchinnikov S. V. , Solovyov N. O.
Published: November 2023

Currently, the issue of coronavirus infection COVID-19 remains extremely relevant, and the SARS-CoV-2 virus also affects the gastrointestinal tract, and in some cases, coronavirus infection can be complicated by gastrointestinal bleeding. Up to 13% of COVID-19 patients have this complication. At the same time, the issue of determining risk factors for the development of gastrointestinal bleeding in patients with COVID-19 remains unresolved in the world literature. There is no single standardized approach to the treatment of gastrointestinal bleeding in patients with COVID-19. The above reasons served as prerequisites for this literature review. The purpose of the literature review is to establish risk factors and groups for gastrointestinal bleeding in patients with a new coronavirus infection, and to determine current and effective methods of treating this disease.