bluuebunny/crossref_metadata_2025 huggingface dataset:
Die Europium(II)-Oxidhalogenide Eu2OBr2 und Eu2OI2
Authors: Rudolph Daniel , Schleid Thomas
Published: October 2017

The syntheses and crystal structures of the two isotypic europium(II) oxide halides Eu2OBr2 and Eu2OI2 are reported. They crystallize orthorhombically in the space group Ibam (Z=4; Eu2OBr2: a=709.86(5), b=1200.34(9), c=628.71(4) pm; Eu2OI2: a=739.78(5), b=1295.13(9), c=644.82(4) pm). The unit cell parameters presented here, and thus the interatomic distances of Eu2OI2, are significantly smaller than the ones reported in the literature, which is explained by the substitution of europium with larger barium cations due to the synthesis route described in the early study. Central building blocks of both crystal structures are trans-edge-connected [OEu4]6+ tetrahedra forming straight

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chains running parallel to the [001] direction. Bundled like a hexagonal rod packing, their interaction is achieved by Br− or I− anions for charge compensation.
Longitudinal Changes in Body Composition Throughout Successive Seasonal Phases Among Canadian University Football Players
Authors: Kim Justin , Delisle-Houde Patrick , Reid Ryan E. R. , Andersen Ross E.
Published: October 2017

Kim, J, Delisle-Houde, P, Reid, RER, and Andersen, RE. Longitudinal changes in body composition throughout successive seasonal phases among Canadian university football players. J Strength Cond Res 32(8): 2284–2293, 2018—The purpose of this study was to assess changes in body composition during seasonal phases of the training year among Canadian Inter-University Sport (CIS) football players. Forty university football players were assessed for anthropometry, total body composition, regional body composition, and central adiposity over a 7-month period including the summer off-season and the in-season. Baseline testing occurred in April, before the summer off-season, and follow-ups were completed before training camp, at the beginning of August, and following the in-season, at the beginning of November. Linemen had the greatest tissue percent fat (25.98 ± 6.56%) at baseline, significantly (p < 0.01) greater than big skill (18.69 ± 3.97%) and followed by skill (14.35 ± 3.39%) who were significantly (p < 0.01) leaner than both other groups. Skill players significantly increased fat mass (0.98 ± 0.30 kg, p ≤ 0.05) and waist-to-hip ratio (0.02 ± 0.01, p ≤ 0.05) during the in-season, and linemen increased visceral fat mass from April to November (0.20 ± 0.06 kg, p ≤ 0.01). All players significantly (−1.26 ± 0.30 kg, p = 0.001) decreased lean mass during the in-season. All groups significantly increased bone mineral content during the summer off-season (p ≤ 0.05). There was also a significant time × summer training location interaction (p ≤ 0.05) for fat mass with athletes who remained on campus during summer months gaining the least amount of adiposity. Body composition and central adiposity seem to change differentially among positional groups across the annual training season.
Modified–Thermal Borehole Shear Test Device and Testing Procedure to Investigate the Soil-Structure Interaction of Energy Piles
Authors: Xiao Suguang , Suleiman Muhannad T. , Naito Clay , Al-Khawaja Mohammed
Published: October 2017

The intermittent operation of heat pumps connected to energy piles causes cyclic variation of temperature in the pile and surrounding soil, affecting the soil-pile interaction in ways that have not been fully investigated or directly measured. The temperature variation and cycles produce expansion and contraction of the pile in both the axial and radial directions and affect soil properties. In this study, a fully automated modified–thermal borehole shear test (Modified-TBST) device was developed to measure the thermo-mechanical behavior of the soil-pile interface properties considering the effects of radial expansion/contraction and temperature variation and cycles. Unlike other devices, the developed Modified-TBST device is fully automated and capable of combining the effects of temperature cycles with radial expansion/contraction (displacement) cycles or separating their effects. This paper describes the testing device, including the control method for expansion/contraction displacement cycles, the calibration of the shear head under non-isothermal conditions, and the measured load and displacement controls during the shearing stage. Furthermore, the paper presents procedure recommendations for performing the soil-pile interface tests, simulating energy piles and presenting preliminary results of shear stress-vertical displacement (t-z curves), considering temperature and displacement effects.
Effect of diabetes status and hyperglycemia on global DNA methylation and hydroxymethylation
Authors: Pinzón-Cortés Jairo Arturo , Perna-Chaux Angelina , Rojas-Villamizar Nicolás Steven , Díaz-Basabe Angélica , Polanía-Villanueva Diana Carolina , Jácome María Fernanda , Mendivil Carlos Olimpo , Groot Helena , López-Segura Valeriano
Published: October 2017

Type 2 diabetes mellitus (T2DM) is characterized by oxidative stress that could lead to chronic micro- and macrovascular complications. We hypothesized that some of the target organ damage is mediated by oxidative alterations in epigenetic mechanisms involving DNA methylation (5mC) and DNA hydroxymethylation (5hmC). We analyzed global DNA methylation and hydroxymethylation in peripheral blood cells in well-controlled and poorly controlled patients with T2DM and compared them with healthy controls. We also analyzed microarrays of DNA methylation and gene expression of other important tissues in the context of diabetes from the GEO database repository and then compared these results with our experimental gene expression data. DNA methylation and, more importantly, DNA hydroxymethylation levels were increased in poorly controlled patients compared to well-controlled and healthy individuals. Both 5mC and 5hmC measurements were correlated with the percentage of glycated hemoglobin, indicating a direct impact of hyperglycemia on changes over the epigenome. The analysis of methylation microarrays was concordant, and 5mC levels were increased in the peripheral blood of T2DM patients. However, the DNA methylation levels were the opposite of those in other tissues, such as the pancreas, adipose tissue and skeletal muscle. We hypothesize that a process of DNA oxidation associated with hyperglycemia may explain the DNA demethylation in which the activity of ten-eleven translocation (TET) proteins is not sufficient to complete the process. High levels of glucose lead to cellular oxidation, which triggers the process of DNA demethylation aided by TET enzymes, resulting in epigenetic dysregulation of the damaged tissues.
Thyroid hormone regulates protease expression and activation of Notch signaling in implantation and embryo development
Authors: Piccirilli Diletta , Baldini Enke , Massimiani Micol , Camaioni Antonella , Salustri Antonietta , Bernardini Roberta , Centanni Marco , Ulisse Salvatore , Moretti Costanzo , Campagnolo Luisa
Published: October 2017

A clinical association between thyroid dysfunction and pregnancy complications has been extensively reported; however, the molecular mechanisms through which TH might regulate key events of pregnancy have not been elucidated yet. In this respect, we performed in vivo studies in MMI-induced hypothyroid pregnant mice, evaluating the effect of hypothyroidism on the number of implantation sites, developing embryos/resorptions and pups per litter, at 4.5, 10.5, 18.5 days post-coitum (dpc) and at birth. We also studied the expression of major molecules involved in implantation and placentation, such as the proteases ISPs, MMPs, TIMPs and Notch pathway-related genes. Our results demonstrate that hypothyroidism may have a dual effect on pregnancy, by initially influencing implantation and by regulating placental development at later stages of gestation. To further elucidate the role of TH in implantation, we performed in vitro studies by culturing 3.5 dpc blastocysts in the presence of TH, with or without endometrial cells used as the feeder layer, and studied their ability to undergo hatching and outgrowth. We observed that, in the presence of endometrial feeder cells, TH is able to anticipate blastocyst hatching by upregulating the expression of blastocyst-produced ISPs, and to enhance blastocyst outgrowth by upregulating endometrial ISPs and MMPs. These results clearly indicate that TH is involved in the bidirectional crosstalk between the competent blastocyst and the receptive endometrium at the time of implantation.
Antidiabetic therapies and male reproductive function: where do we stand?
Authors: Tavares R S , Escada-Rebelo S , Silva A F , Sousa M I , Ramalho-Santos J , Amaral S
Published: October 2017

Diabetes mellitus has been increasing at alarming rates in recent years, thus jeopardizing human health worldwide. Several antidiabetic drugs have been introduced in the market to manage glycemic levels, and proven effective in avoiding, minimizing or preventing the appearance or development of diabetes mellitus-related complications. However, and despite the established association between such pathology and male reproductive dysfunction, the influence of these therapeutic interventions on such topics have been scarcely explored. Importantly, this pathology may contribute toward the global decline in male fertility, giving the increasing preponderance of diabetes mellitus in young men at their reproductive age. Therefore, it is mandatory that the reproductive health of diabetic individuals is maintained during the antidiabetic treatment. With this in mind, we have gathered the available information and made a critical analysis regarding the effects of several antidiabetic drugs on male reproductive function. Unlike insulin, which has a clear and fundamental role on male reproductive function, the other antidiabetic therapies' effects at this level seem incoherent. In fact, studies are highly controversial possibly due to the different experimental study approaches, which, in our opinion, suggests caution when it comes to prescribing such drugs to young diabetic patients. Overall, much is still to be determined and further studies are needed to clarify the safety of these antidiabetic strategies on male reproductive system. Aspects such as the effects of insulin levels variations, consequent of insulin therapy, as well as what will be the impact of the side effect hypoglycemia, common to several therapeutic strategies discussed, on the male reproductive system are still to be addressed.
Architecture and Distribution of Introns in Core Genes of FourFusariumSpecies
Authors: Phasha Mmatshepho M , Wingfield Brenda D , Coetzee Martin P A , Santana Quentin C , Fourie Gerda , Steenkamp Emma T
Published: October 2017

Removal of introns from transcribed RNA represents a crucial step during the production of mRNA in eukaryotes. Available whole-genome sequences and expressed sequence tags (ESTs) have increased our knowledge of this process and revealed various commonalities among eukaryotes. However, certain aspects of intron structure and diversity are taxon-specific, which can complicate the accuracy of in silico gene prediction methods. Using core genes, we evaluated the distribution and architecture of Fusarium circinatum spliceosomal introns, and linked these characteristics to the accuracy of the predicted gene models of the genome of this fungus. We also evaluated intron distribution and architecture in F. verticillioides, F. oxysporum, and F. graminearum, and made comparisons with F. circinatum. Results indicated that F. circinatum and the three other Fusarium species have canonical 5′ and 3′ splice sites, but with subtle differences that are apparently not shared with those of other fungal genera. The polypyrimidine tract of Fusarium introns was also found to be highly divergent among species and genes. Furthermore, the conserved adenosine nucleoside required during the first step of splicing is contained within unique branch site motifs in certain Fusarium introns. Data generated here show that introns of F. circinatum, as well as F. verticillioides, F. oxysporum, and F. graminearum, are characterized by a number of unique features such as the CTHAH and ACCAT motifs of the branch site. Incorporation of such information into genome annotation software will undoubtedly improve the accuracy of gene prediction methods used for Fusarium species and related fungi.
Regulation of Axon Guidance by the Wnt Receptor Ror/CAM-1 in the PVT Guidepost Cell in Caenorhabditis elegans
Authors: Chien Jason , Devkota Ranjan , Yosef Nebeyu , Mörck Catarina
Published: October 2017

The Caenorhabditis elegans ventral nerve cord (VNC) consists of two asymmetric bundles of neurons and axons that are separated by the midline. How the axons are guided to stay on the correct sides of the midline remains poorly understood. Here we provide evidence that the conserved Wnt signaling pathway along with the Netrin and Robo pathways constitute a combinatorial code for midline guidance of PVP and PVQ axons that extend into the VNC. Combined loss of the Wnts CWN-1, CWN-2, and EGL-20 or loss of the Wnt receptor CAM-1 caused >70% of PVP and PVQ axons to inappropriately cross over from the left side to the right side. Loss of the Frizzled receptor LIN-17 or the planar cell polarity (PCP) protein VANG-1 also caused cross over defects that did not enhance those in the cam-1 mutant, indicating that the proteins function together in midline guidance. Strong cam-1 expression can be detected in the PVQs and the guidepost cell PVT that is located on the midline. However, only when cam-1 is expressed in PVT are the crossover defects of PVP and PVQ rescued, showing that CAM-1 functions nonautonomously in PVT to prevent axons from crossing the midline.
A formação cultural como ferramenta básica do Design: entrevista com Norberto Chaves
Authors: Weber Karina Pereira , Brisolara Daniela Velleda , Luz Louise Gonçalves da
Published: October 2017

Entrevista realizada em 28 de julho de 2016 com Norberto Chaves, professor, pesquisador e participante ativo dos Congressos de Ensino de Design da Universidad de Palermo (Buenos Aires, Argentina), concedeu-nos essa entrevista após suas várias palestras realizadas neste evento. Suas falas permearam as temáticas de cultura, marcas, formação do designer e papel do design no contexto socioeconômico e cultural. O autor esclareceu que o design, desde sempre, possui funções importantes para a economia. Fora desse contexto, o design perde o foco de sua existência, uma vez que nasceu nesse contexto: com fins de contribuir para o desenvolvimento econômico e no modo de vida dos indivíduos. Portanto, enquadra-se como um produto cultural, sobretudo porque faz parte da comunicação, ação inerente aos seres humanos.
Uma discussão sobre a utilidade do design através do foco emocional
Authors: Oliveira Rômulo Linhares de , Weber Karina Pereira
Published: October 2017

O presente artigo tem como objeto discutir como o design emocional interfere na vida do ser humano diariamente e em suas relações interpessoais e com o ambiente que o cerca. Será feita uma reflexão sobre onde se pode encontrar o design e como a vida das pessoas se tornaria sem essa atividade. Esse trabalho irá abordar questões como a função dos produtos (prática, estética e simbólica) e que tipo de relação esses produtos mantêm com o seu usuário. O trabalho será apresentado através de um foco simbólico e emocional para que, ao final, seja possível estabelecer um diálogo sobre a utilidade do design.
A versatilidade da roupa feminina e a luta diária da mulher durante a segunda guerra mundial
Authors: Silveira Laiana Pereira da , Schneid Frantieska Huszar
Published: October 2017

Este artigo aborda a questão da vestimenta feminina durante o período da Segunda Guerra Mundial e a versatilidades das peças usadas pelas mulheres que precisaram sair de casa para trabalhar, resgata a importância dessas mulheres que mostraram ao mundo a força da sua independência, mulheres que passaram a serem vistas de frágeis a verdadeiras guerreiras, que precisaram sair do conforto de suas casas paratrabalhar e sustentar suas famílias. Também é discutida a influência da vestimenta masculina no guarda-roupa feminino, devido aos uniformes usados pelos soldados e a questão da regulamentação para a criação das peças de vestuário devido à escassez de matéria-prima.
Uma cultura mutante: o chimarrão e seus artefatos analisados sob o viés do design vernacular e do imaginário
Authors: Assunção Alexandre Vergínio , Arnoni Rafael Klumb , Machado Júnior Luiz Antônio Pereira
Published: October 2017

O chimarrão sofre ao longo do tempo mudanças, tanto no seu simbolismo quanto na forma dos artefatos necessários à sua utilização. Essas incorporaçõesservem como uma rica fonte de pesquisa ao design vernacular e aos estudos do imaginário. Neste artigo trazemos uma síntese analítica sobre aspectos culturais, imaginários, simbólicos e técnicos do chimarrão através de pesquisa bibliográficae iconográfica, no âmbito da hermenêutica simbólica - que se define como interpretação compreensiva do sentido das produções e memórias humanas (RICOEUR, 2009; DURAND, 1996), buscando-se contextualizar sua utilização nos dias atuais. As conclusões revelam que os grupos e as segmentações de uso, em um tempo histórico, sempre interpretam e reelaboram aquilo que neste campo lhes é oferecido, transformando esses artefatos em elementos heterogêneos.
A mediação estética como base investigativa para a definição de um estatuto epistemológico para o Campo do Design
Authors: Heinrich Fabiana Oliveira
Published: October 2017

Este artigo propõe uma investigação no Campo do Design a partir de um estudo da disciplina da Estética e sua capacidade de mediação na construção de artefatos culturais, com vistas à definição de um estatuto epistemológico para o Campo em questão. Ao tomar os escritos de Eagleton (A ideologia da Estética, 1993), Wolff (A produção social da Arte, 1982) e Harvey (Condição pós-moderna, 2010), problematizamos a noção hegemônica de que elementos estéticos podem ser compreendidos por si mesmos, e apontamos para a presença de um caráter ideológico que orienta a sua construção, uso e reprodução. Com efeito, buscamos compreender, no Campo do Design, como a Estética reproduz e materializa valores econômicos, políticos e sociais, e como tal reprodução deve ser considerada no estudo e na configuração de produtos do supracitado Campo.
Medical ‘e-learning’ and the user experience
Authors: Boules Christiana , Malawana Johann
Published: October 2017

This article was migrated. The article was not marked as recommended.
Looking back over 40 years in medical education – the continuing challenge of developing professional artistry and personal educational philosophy
Authors: Sandars John
Published: October 2017

This article was migrated. The article was marked as recommended.

Experienced medical educators appear to focus more on their research than developing their professional artistry and personal educational philosophy. This situation has potential major implications for the continuing improvement of teaching and student learning.
MYH9 E1841K Mutation Augments Proteinuria and Podocyte Injury and Migration
Authors: Cechova Sylvia , Dong Fan , Chan Fang , Kelley Michael J. , Ruiz Phillip , Le Thu H.
Published: October 2017

Intronic variants of the MYH9 gene that encodes the nonmuscle myosin heavy chain IIA are associated with diabetic nephropathy in European Americans and with sickle cell disease–associated nephropathy. However, the causal functional variants of MYH9 have remained elusive. Rare missense mutations in MYH9 cause macrothrombocytopenia and are occasionally associated with development of nephropathy. The E1841K mutation is among the common MYH9 missense mutations and has been associated with nephropathy in some carriers. To determine the contribution of the E1841K mutation in kidney disease, we studied the effects of the E1841K mutation in mice subjected to high salt or angiotensin II (Ang II) as models of hypertension and in mice subjected to renal mass reduction as a model of CKD. Despite similar levels of BP among wild-type (MYH9+/+
) mice and mice heterozygous (MYH9+/E1841K
) and homozygous (MYH9E1841K/E1841K
) for the mutation in each model, MYH9E1841K/E1841K
mice exhibited mildly increased albuminuria in response to high salt; severe albuminuria, nephrinuria, FSGS, and podocyte foot effacement in Ang II–induced hypertension; and early mortality in the renal mass reduction model. Treatment with candesartan during Ang II–induced hypertension attenuated kidney disease development in MYH9E1841K/E1841K
mice. In vitro, isolated primary podocytes from MYH9E1841K/E1841K
mice exhibited increased lamellipodia formation and reorganization of F-actin stress fibers. Wound healing assays revealed that MYH9+/+
podocytes had the lowest migration rate, followed by MYH9+/E1841K
then MYH9E1841K/E1841K
podocytes. In conclusion, the MYH9 E1841K variant alters podocyte cytoskeletal structure and renders podocytes more susceptible to injury after a damaging stimulus.
Factor H Competitor Generated by Gene Conversion Events Associates with Atypical Hemolytic Uremic Syndrome
Authors: Goicoechea de Jorge Elena , Tortajada Agustín , García Sheila Pinto , Gastoldi Sara , Merinero Héctor Martín , García-Fernández Jesús , Arjona Emilia , Cao Mercedes , Remuzzi Giuseppe , Noris Marina , Rodríguez de Córdoba Santiago
Published: October 2017

Atypical hemolytic uremic syndrome (aHUS), a rare form of thrombotic microangiopathy caused by complement pathogenic variants, mainly affects the kidney microvasculature. A retrospective genetic analysis in our aHUS cohort (n=513) using multiple ligation probe amplification uncovered nine unrelated patients carrying a genetic abnormality in the complement factor H related 1 gene (CFHR1) that originates by recurrent gene conversion events between the CFH and CFHR1 genes. The novel CFHR1 mutants encode an FHR-1 protein with two amino acid substitutions, L290S and A296V, converting the FHR-1 C terminus into that of factor H (FH). Next-generation massive-parallel DNA sequencing (NGS) analysis did not detect these genetic abnormalities. In addition to the CFHR1 mutant, six patients carried the previously uncharacterized CFH-411T variant. In functional analyses, the mutant FHR-1 protein strongly competed the binding of FH to cell surfaces, impairing complement regulation, whereas the CFH-411T polymorphism lacked functional consequences. Carriers of the CFHR1 mutation presented with severe aHUS during adulthood; 57% of affected women in this cohort presented during the postpartum period. Analyses in patients and unaffected carriers showed that FH plasma levels determined by the nonmutated chromosome modulate disease penetrance. Crucially, in the activated endothelial (HMEC-1) cell assay, reduced FH plasma levels produced by the nonmutated chromosome correlated inversely with impairment of complement regulation, measured as C5b-9 deposition. Our data advance understanding of the genetic complexities underlying aHUS, illustrate the importance of performing functional analysis, and support the use of complementary assays to disclose genetic abnormalities not revealed by current NGS analysis.
Pollination biology of Agave horrida (Agavaceae) in the Chichinautzin mountain range, in Central Mexico”
Authors: Flores-Torres Arnoldo , Galindo-Escamilla Andrea
Published: October 2017

Background: the predictability of nectarivorous bats and their greater fecundity efficiency promote specialized pollination systems in columnar cactus in central Mexico. Some authors have suggested the same pollination pattern for Agave genus, and even when recent meta-analysis does not find such pattern, they have suggested this could be due to the lack of descriptive studies of pollination for this genus.
Hypothesis: according to the chiropterophily syndrome of its flowers, the most efficient pollinator of Agave horrida will be nectarivorous bats leading to a pollination system with a specialist tendency in this agave species.
Studied species: Agave horrida and floral visitors.
Study site and years of study: lava field of the Chichinautzin mountain range, in Morelos State in Central Mexico in 2005.
Methods: we studied the floral biology of A. horrida, its floral offer (density of flowers in a given area), visitor rate, and visitor abundance, and conducted exclusion experiments for diurnal and nocturnal visitors.
Results: A. horrida has protandric flowers with chiropterophilous characteristics (larger nectar production at night and nocturnal anther dehiscence and stigma receptivity). Nectarivorous bats were the most frequent flower visitors and the guild that most frequently presented pollen on their bodies. Pollinator exclusion experiments show that both birds and bats can successfully pollinate A. horrida.  Nevertheless, the predictability and abundance of the nectarivorous bat Leptonycteris nivalis, along with the greater fruit and seed production than birds, makes it the most efficient pollinator.
Conclusions: our results support the hypothesis of a specialized pollination system towards nectarivorous bats in agaves in central Mexico.
La figura de Babilonia en el libro de Apocalipsis
Authors: Reynolds Edwin
Published: October 2017

“La figura de Babilonia en el libro de Apocalipsis” ─ La figura deBabilonia es parte de una temática dentro del libro de Apocalipsis que elautor denomina como “el tema de la ‘Gran Ciudad’”. Apocalipsis presentados ciudades contrapuestas; una de ellas es la Gran Ciudad, y la otra es laSanta Ciudad. La Santa Ciudad es la Nueva Jerusalén, la Novia de Cristo.Por otro lado, la Gran Ciudad es la antagonista de Cristo, la enemigade Dios y de su pueblo. Esta es identificada en el Apocalipsis de variasformas, como Sodoma, Egipto y Babilonia, que son conceptos clave quehallan su significado en contextos y tradiciones bíblicos.
En defensa del principio de “día por año”
Authors: Pfandl Gerhard
Published: October 2017

“En defensa del principio de ‛día por año’” ─ El autor señala queuno de los pilares principales del método de interpretación historicistaes su principio de “día por año”, el cual afirma que un día —en las profecíasde tiempo— representa un año. Durante el siglo XIX, el métodohistoricista fue paulatinamente desplazado por los sistemas de interpretaciónpreterista y futurista, los cuales niegan el principio de “día poraño”. El preterismo ubica a la mayoría de las profecías en el pasado,relegándolas solo hasta los días del imperio romano; el futurismo ubicaa la mayor parte de ellas en el futuro, suponiéndolas especificamente,en los últimos siete años que transcurrirían entre el rapto secreto y lasegunda venida. A su vez, el autor señala que hoy el historicismo aúnprevalece en las filas de la Iglesia Adventista como su método de interpretaciónde las profecías bíblicas.
“La teología de la creación según Martín Lutero en sus lecciones sobre el Génesis”
Authors: Kaiser Denis
Published: October 2017

“La teología de la creación según Martín Lutero en sus leccionessobre el Génesis”— Martín Lutero comenzó a dar lecciones sobre el librodel Génesis en el año 1535. Este artículo se enfoca específicamente en suslecciones sobre el relato bíblico de la creación tal como se encuentra en Gen1:1-2:4 y aborda los temas que aparentemente eran especialmente importantespara el reformador alemán, ya que él los menciona repetidamente ensus lecciones. La primera parte trata las presuposiciones básicas de Luteroacerca de la autoridad de las fuentes, los conceptos de tiempo y espacio, y lanaturaleza de Dios. La segunda parte discute los diferentes aspectos de lacreación como un acto divino de benevolencia. Según su punto de vista, Dioscreó ex nihilo en seis días literales, y la creación fue una manifestación de labenevolencia de Dios. El sábado fue una señal de su benevolencia. Lutero nocreía en la creación como un evento pasado, sino también como una actividaddivina continua. Esto se refleja en los incesantes actos de preservación,gobierno y creación de Dios. Además, el relato de la creación tiene un propósitoespiritual y moral para el lector contemporáneo, y puede servir comoun tipo del futuro. El énfasis principal de Lutero no estaba puesto tanto en elconcepto de creatio ex nihilo sino más bien en la idea de que todo fue creado,y es preservado y gobernado per verbum. Aunque Lutero comentó todos losversículos del relato mosaico de la creación, se enfocó específicamente en lasactividades divinas. Las actividades creadoras, preservadoras, gobernantes yrecreadores de la Palabra se destacan nítidamente.
ESCENARIO DE CAMBIO CLIMÁTICO A NIVEL DE SUBCUENCAS HIDROGRÁFICAS PARA EL AÑO 2050 DE LA PROVINCIA DE CHIMBORAZO- ECUADOR
Authors: Bustamante Diana Patricia
Published: October 2017

El presente estudio se realizó en la provincia de Chimborazo-Ecuador con el propósito de establecer un escenario de
cambio climático para el año 2050, a fin de implementar políticas públicas en el Plan de Desarrollo y Ordenamiento
Territorial que ayuden a reducir la vulnerabilidad de la población ante los riesgos climáticos. Para ello, se analizó
información a nivel de subcuencas hidrográficas con una resolución espacial de 1 km2 en un escenario de radiación
de 2,6 RCP, corresponde a un Modelo Global de Circulación (GCM) denominado MIROC-ESM-CHEM. En la definición
del escenario, se utilizó información a una escala 1:4000000 más detallada generada por WorldClim ya que la
información climática disponible de modelos como PRECIS, TL959 generados para el Ecuador, tienen un detalle muy
bajo con una grilla de 50 km2, escala 1:282 800 000, que para el caso de la provincia es una gran limitante considerando
que de la información se obtuvo resultados para nivel de subcuencas. Al comparar el escenario actual y el de cambio
climático para el año 2050, en los datos se observó variaciones climáticas principalmente reducción de la precipitación
en las subcuencas: río Namangoza, río Patate y río Chambo; así como, un incremento de la temperatura mínima y
máxima en la subcuenca río Namangoza.
PERCEPTION STUDY OF BENEFITS OF SOCIO BOSQUE PROGRAMME IN ECUADORIAN AMAZON REGION
Authors: GRANDA María José , YANEZ-MORETTA PATRICIO
Published: October 2017

El presente estudio explora aspectos relacionados con la conservación de bosques nativos del occidente de la región
amazónica ecuatoriana (provincias de Napo, Pastaza y Morona Santiago) y la relación de ésta con algunas variables
sociales y económicas. Los datos se generaron en ciento veinte y dos predios de dos grupos de finqueros: unos pertenecientes
a la iniciativa Socio Bosque y otros no, la fase de campo se realizó entre febrero a marzo de 2014. En la
información recogida, se incluyeron aspectos geográficos, sociales, laborales, de uso del suelo y de actividades futuras.
Entre otros resultados, se evidencia que la mayoría de propietarios desea mantener sus zonas boscosas con
especies nativas, pero manifiesta la necesidad de contar con capacitaciones más frecuentes en torno a la dinámica de
los ecosistemas locales y las formas más idóneas para cuidarlos.
EVALUACIÓN IN VITRO DE LA REMOCIÓN DE PLOMO EN AGUAS RESIDUALES POR Photobacterium damselae
Authors: Cando Lenin Javier Ramirez , Guerra Santiago , Reinoso Gabriela
Published: October 2017

Con la finalidad de mitigar los impactos ambientales ocasionados por plomo en aguas residuales de sectores como:
minero, petroquímico, metalúrgico, otros, se realizó una evaluación in vitro de la remoción de plomo utilizando Photobacterium
damselae. En la fase de aislamiento y bioestimulación las cepas obtenidas fueron sometidas a un proceso de
selección en un medio de cultivo modificado, al cual se añadieron concentraciones de 20 y 100 ppm de Pb, obteniendo
finalmente la cepa pura que mostró resistencia y/o tolerancia al Pb. La determinación de la capacidad para remover
Pb en aguas residuales se observó en dos condiciones: incubación en temperatura controlada (25C) e incubación en
temperatura ambiente de Quito-Ecuador (zona sur a 2 800 msnm). La caracterización bioquímica de la bacteria fue
realizada utilizando el Kit de Microgen GN-ID A+B. En la elaboración de las curvas de cinética de crecimiento bacteriano
y remoción de Pb, se utilizaron técnicas de turbidimetría y absorción atómica, se destaca que Photobacterium
damselae presentó una mayor facilidad de crecimiento a un máximo de 72 horas y a una concentración de 20 ppm en
incubación a temperatura ambiente lográndose una remoción de hasta el 69% del plomo en el medio. De lo cual se
infiere el potencial que tiene esta bacteria y se abren oportunidades para continuar estudios a futuro.
SEROPREVALENCIA DE LEUCOSIS ENZOÓTICA BOVINA EN ANIMALES ENTRE 6 A 24 MESES EN LAS PROVINCIAS DE MANABÍ, PICHINCHA Y CHIMBORAZO - ECUADOR
Authors: Puga Torres Byron Humberto , Vásconez-Hernández Adriana , Sandoval-Valencia Patricio , De La Cueva-Jácome Francisco
Published: October 2017

La Leucosis Enzoótica Bovina (LEB o LVB) es una enfermedad vírica, manifestada por la presencia de neoplasiasy también presentándose de forma asintomática en bovinos de cualquier edad. Su trascendencia socioeconómicaradica en las pérdidas por disminución de la productividad lechera, pérdidas reproductivas y decomisos en camales,impidiendo también la exportación de ganado o derivados del mismo. El objetivo de esta investigación fue determinarla seroprevalencia de LEB en animales menores de dos años en las provincias de Pichincha, Manabí y Chimborazo,las cuales reportan gran producción lechera en Ecuador. Se analizaron 3 307 muestras de suero sanguíneo bovinomediante la técnica serológica ELISA indirecto, de las cuales 480 fueron de Pichincha, 2 348 de Manabí y 479 deChimborazo. Pichincha presentó una seroprevalencia de 8.13%, con el mayor porcentaje de animales enfermos enla principal cuenca lechera del país, el cantón Mejía. En Manabí se observó 0.89% de seroprevalencia de LEB y enChimborazo 3.13%. Utilizando chi cuadrado para determinar la relación entre las variables evaluadas y la apariciónde LEB, se reveló que no existe asociación, mostrando un resultado de 105.14, 7.48, 140.91 y 38.87 frente a valores dep de 11.34 (clima), 9.21 (altitud), 18.48 (edad) y 9.21 (propósito del ganado). Sin embargo, se observó mayor tendenciaa enfermar en clima templado y mayor altitud, lo que pudo explicarse por la similitud en las prácticas de manejoy la explotación tipo intensivo. Los datos obtenidos significan una línea base de estudio de la cual se puede partirpara elaborar un plan de control sanitario de LEB desde edades tempranas del ganado bovino y emprender en otrasinvestigaciones.
Cinco regímenes políticos en Latinoamérica, libertad de internet y mecanismos de control
Authors: Puyosa Dra. Iria , Chaguaceda Dr. Armando
Published: October 2017

Desde 2010 se ha observado una tendencia al establecimiento de políticas de control y securitización de internet (Freedom House, 2016). En la literatura sobre el tema se indica que los mecanismos de control de internet varían según el tipo de regímenes políticos. El objetivo de este trabajo es observar si las políticas de control de internet en Latinoamérica varían según el tipo de régimen político imperante.
Para el estudio se seleccionaron cinco países latinoamericanos que son categorizados como ejemplos de distintos regímenes políticos: Chile, México, Ecuador, Venezuela y Cuba. Para cada uno de los casos, se reportan los indicadores relativos a la libertad de expresión en internet vigentes de acuerdo con los datos proporcionados por «Varieties of Democracy». Como complemento se usan las categorizaciones de «Freedom on the Net». Los resultados indican que efectivamente existe correlación entre régimen político (medido por índice de poliarquía) y libertad de internet. Mientras más autocrático es el régimen
más se observan controles de internet de primera generación, con censura de contenidos y violaciones a los derechos de los usuarios. Mientras que en los regímenes híbridos se observan más comúnmente controles de segunda generación, que involucran obstáculos al acceso, sin que se llegue al bloqueo de
contenidos y a los apagones de la red.
Vigilia y vigilancia: Análisis de contenido del Registro Nacional de Acceso a Internet en Brasil
Authors: Nobre Cavalcante Fernando
Published: October 2017

La legalización e institucionalización de la vigilancia de las informaciones digitales de los ciudadanos brasileños han sido promovidas por intereses de grupos políticos protestantes que argumentan ideas de fe y moralidad en proyectos de leyes que potencian nuevas formas de control de Internet. Desde
2015, diferentes proyectos de ley amenazan el derecho a la privacidad y a la libertad de expresión en las comunicaciones digitales, garantizados por la Ley Nº 12.965, del 23 de abril de 2014 (Marco Civil de Internet). La presente investigación analiza los puntos críticos de los proyectos de normativas de control de Internet promovidos por políticos evangélicos y justificados en argumentos morales de protección de niños y adolescentes. El presente artículo establece un diálogo teórico con los postulados de Manuel Castells en un intento por desmitificar los argumentos a favor del control y utiliza una investigación
cualitativa por medio de un levantamiento y análisis de contenido de los proyectos de leyes que aún se tramitan en el Congreso Nacional brasileño. Se evidencia que los actuales proyectos de ley establecen amenazas fecundas en los principios orientadores, garantías, derechos y deberes para el uso de Internet en Brasil, camuflados en narrativas moralistas y de argumentos disonantes e interesados de la Ley Nº 12.965, llevando al entendimiento que hay eminentes posibilidades de ampliación del control y vigilancia de las informaciones que consumen y producen los internautas brasileños.
Una aproximación teórica para mejorar los resultados de innovación en las empresas desde la perspectiva del “Happiness Management”
Authors: Ravina Ripoll Dr. Rafael , Villena Manzanares Dr. Francisco , Gutiérrez Montoya Dr. Guillermo Antonio
Published: October 2017

En el presente artículo, se plantea una reflexión sobre cómo aumenta la productividad de la empresa cuando se fomenta el bienestar corporativo. Se presenta un modelo teórico que va en varias fases en las cuales se esbozan las etapas que deben interactuar para dar soluciones a problemas en las organizaciones en el presente siglo. Las actuales tendencias de la administración ya empiezan a considerar los principios o filosofía del «Happiness Management» como futuras tendencias que pueden aplicarse a cualquier organización
independientemente del sector donde operen. Por eso se hace necesario implantar culturas dispuestas a conseguir resultados competitivos y sostenibles en la empresa, renovando con ello en primer lugar el bienestar corporativo y en consecuencia su productividad laboral, y en segundo lugar mejorando el rendimiento organizativo generando competitividad. Por último, la cultura de innovación basada en incrementar el bienestar corporativo mejora la imagen de la compañía proyectándose positiva hacia todos sus stakeholders.
Mejores prácticas empresariales de responsabilidad social en la inclusión de personas con discapacidad. Estudio de caso en empresas de Ambato, Ecuador
Authors: Pico Barrionuevo Fanny Paulina , Torres Silvia Susana
Published: October 2017

La inclusión de las Personas con Discapacidad (PcD) en el ámbito laboral aún tiene falencias que se debe ir corrigiendo, considerando que este grupo ha sentido la exclusión laboral de alguna u otra forma. El sector empresarial, protagonista principal del mercado laboral y actor fundamental en la realización
de una verdadera inclusión, ya sea por cumplimiento de normativas legales establecidas o a su vez por realizar Responsabilidad Social Empresarial, tiene en sus manos la inclusión laboral de personas con esta condición. El objetivo del presente trabajo es identificar la realidad de las empresas en la inclusión
laboral de las personas con discapacidad. Para el efecto se aplica un diseño metodológico de tipo cuali-cuantitativo en base a un marco teórico revisado para luego identificar valoraciones que permitan reunir evidencias y emitir un juicio de valor en la investigación. Se aplica el tipo de muestra probabilística aleatoria
simple a través de la cual cada elemento de la población tiene la misma oportunidad de ser elegida. La investigación se realiza a través de una encuesta establecida de cuatro dimensiones: i) planificación; ii) inclusión; iii) equidad y; iv) desarrollo. De las 80 empresas encuestadas, el 11,70% corresponden a
aquellas que realizan las mejores prácticas empresariales. También destaca el sector comercial en los ejes de inclusión, equidad y desarrollo. El eje de desarrollo es el que tiene menor porcentaje, por lo que se le debe considerar con mayor interés para mejorar los procesos de inclusión de PcD.
Circulación y distribución de cine etnográfico en América Latina
Authors: Chávez Carvajal Hugo
Published: October 2017

While visual anthropology, as the roof under which is usually wrapped this films, enjoys good health in the region and new educational and research projects are generated every year, It has not been the same with the diffusion, distribution and exhibition despite the long tradition of documentary film linked to the anthropological view in countries such as Argentina, Colombia and Mexico. In the last decade, in parallel, they have significantly changed the logic of consumption and circulation of films. This scene presents new opportunities. The purpose is twofold, on one side analyzes the importance of building spaces for the formation of audiences such as festivals and exhibitions, starting from the premise that the future of every film depends on how it can reach the people. By the other side seeks to provide material for consultation and guidance for those interested in distributing audiovisual works of ethnographic cutting.
Los primeros viajes audiovisuales (1936) de Rolf Blomberg en Ecuador
Authors: Passarelli Franco
Published: October 2017

The objective of this article is to investigate, from the comparative analysis of the films “In Canoe to the Land of the Reductors of Heads” and “Vikings in the Islands of the Giant Tortoises” of Rolf David Blomberg (Sweden, 1912- Ecuador, 1996), the production and reproduction of images of European explorers in Ecuador during the interwar period (1919-1939). The work is mainly focused on the analysis of the film form of both films where the construction of “audio-visual trips” is intended to be discussed.Time, space and subject are left unadjusted at different levels as conclusions of comparative analysis. The questions that will guide this work are: What kind of narratives and imaginaries constructed the “audiovisual journeys” of European explorers / filmmakers in Ecuador? How did these ideas circulate? What is the importance of studying the movement images of this type of explorers / directors from and for Audiovisual Anthropology?
Tejer y Resistir. Etnografías Audiovisuales y Narrativas Textiles
Authors: Rivera García Mariana Xochiquétzal
Published: October 2017

The knitting as narrative has been a very old strategy, used mainly by women, where they have shaped and perpetuated their stories and the story of their towns through a very unique vision. Weaving had have diverse objectives, from the most obvious that is to dress the body, until ritual or political functions.The weaving is a language that can only be understood and transmitted by those who experience it through the body.This article reflects on the development of an audiovisual methodology applied to a P.H.D research about the relation between knitting and memory from an ethnographic, political and resistance perspective, but also as a creative process.This article also explores in the process of filming five documentary videos as a creative approach to the various ethnographic questions that were raised throughout the research, and at the same time, as a way of interacting with the communities of weavers and negotiate my presence in the field. The audiovisualwork, in addition to an exhibition of textiles and workshops, were together the methodological route that allowed to build a bridge to connect weavers at different latitudes, mainly among amuzgas weavers in the State of Guerrero, Mexico and weavers of memory in Colombia. Both collectives were able tostablish a symbolic dialogue through their woven stories. Generating a powerful reflection as women, recognizing the value they deserved to their manual and artistic work related to memory. This process has given those women the possibility to transform positively their lives.
Percepción de la competencia mediática y la formación en maestros chilenos
Authors: Maraver López Pablo , Caldeiro-Pedreira Mari-Carmen , Pérez-Lisboa Sandra
Published: October 2017

This paper analyzes the educational reality of Los Andes area with respect to the technological knowledge that teachers have in the field of new technologies (ICT), it also seeks to know the resources they have in the classroom and the use they make of them. In the study an analytical and quasi-experimental methodology has been used through several surveys (pretest and postest). The data obtained are intended to justify the use of ICT in schools and the knowledge that the participating teachers possess. In addition, attention is focused on the importance of ICTs in the education curriculum in Chile and the pedagogical programs and strategies that exist in Chile.
Assembly Stats with MetaQuast v1
Authors: E Thornton Jr James
Published: October 2017

Calculate various assembly statistics using the MetaQuast app on the CyVerse Discovery Environment.
Fatores genéticos associados ao câncer de mama masculino: uma revisão de literatura
Authors: Silveira Nathalia Maria Tomaz , Doudement Mariana Bezerra , Lucena João Carlos de Alencar , Parente Daniela Moura
Published: October 2017

O câncer de mama masculino é um quadro neoplásico raro, abrange 1% dos casos de câncer de mama no mundo todo, 1% dos tumores malignos em homens e apresenta incidência anual de 1 por 100.000. Reuniram-se informações acerca da atualidade de estudos relacionados ao caráter genético na patologia abordada, cujo objetivo foi analisar aspectos da predisposição e associação, utilizando 15 artigos originais indexados no período entre janeiro de 2011 a fevereiro de 2016, escritos em inglês e espanhol, com delineamento experimental ou observacional, utilizando os descritores câncer de mama masculino, tratamento do câncer, câncer de mama e fator genético do câncer de mama, assim como suas traduções em inglês male breast cancer, cancer treatment, breast cancer e genetic factors. Discutiu-se principalmente a influência genética na ocorrência do câncer de mama masculino, como alterações em genes supressores BRCA, relações com o ponto de checagem CHECK2, histórico familiar e ligações com a síndrome de Klinefelter, entre outros fatores. Aspectos ambientais também são sugeridos por parte da literatura na manifestação clínica da neoplasia, porém com menores ênfases conclusivas. Apesar da literatura sobre o tema ainda necessitar de crescimento e aprofundamento, observaram-se reafirmações científicas sobre a importância da influência genética, sobretudo do BRCA 2, além de confirmações quanto a multifatoriedade da neoplasia.
A genética do glioblastoma e as novas abordagens de tratamento: revisão de literatura
Authors: Santos Marília , Santos Breno , Cristina Marília
Published: October 2017

Os glioblastomas estão entre os cânceres neurais de maior incidência em todo o mundo. Suas características genotípicas e fenotípicas permitem ações diferenciadas que fazem com que grande parte dos tratamentos sejam ineficazes. Esta revisão de literatura tem como objetivo a compreensão da genética do glioblastoma e das novas abordagens terapêuticas com resultados positivos. Foram utilizados como bancos de dados, os seguintes periódicos eletrônicos: LILACS, SCIELO, NCBI e CAPES, sendo consideradas as publicações de 2010 até 2016. A presente literatura demonstra que as ações diferenciadas de migração e reincidência do câncer dificultam os tratamentos convencionais. Os estudos feitos reportam uma nova abordagem terapêutica, utilizando-se adenovírus oncóticos para a quantificação da área de cobertura tumoral e a supressão do crescimento do glioblastoma humano, aumentando a porcentagem de sobrevida e de um tratamento eficaz que possa levará cura dessa doença.