bluuebunny/crossref_metadata_2025 huggingface dataset:
Extreme Precipitation Indices Trend Assessment over the Upper Oueme River Valley-(Benin)
Authors: André Attogouinon André , Lawin Agnidé E. , M’Po Yèkambèssoun N’Tcha , Houngue Rita
Published: July 2017

This study analyzed trends in extreme precipitation based on daily rainfall data provided by Bénin Méteo Agency for the Upper Ouémé valley in Benin over the period 1951–2014. Eleven indices divided into two groups were considered. The first group consists of frequency indices: number of heavy rainfall days, very heavy rainfall days and extremely heavy rainfall days; and maximum number of Consecutive dry days and wet days. The second group concerns intensity: daily maximum rainfall (RX1day), maximum five-day rainfall (RX5day), annual total wet-day rainfall (PRCPTOT), simple daily intensity index (SDII), very wet day (R95P) and extremely wet day rainfall (R99P). The non-parametric Mann-Kendall test was used to assess trends in those indices. The results show that only 30% of the stations experienced decreasing trends for the number of heavy rainfall days (R10mm) and daily maximum rainfall (RX1day). For the annual total wet-day rainfall (PRCPTOT), the simple daily intensity index (SDII) and the very wet day rainfall (R95P), 20% of stations faced significant negative trends. In addition, the decreasing trends are observed for 10% stations considering the number of very heavy rainfall days (R20mm), the maximum five-day rainfall (RX5day) and the extremely wet day rainfall (R99P). About the increasing trend, 10% stations are identified for the number of consecutive dry days (CDD), very heavy rainfall days (R20mm), the daily maximum rainfall (RX1day), the simple daily intensity index, and the extremely wet day rainfall (R99P). These results show the absence of clear trend of climate indices evolution in almost all stations. Consequently, uncertainties in the evolution of rainfall indices must be taken into account in the definition of adaptation strategies for flood or drought risks. Similarly, these results show a slight drop in the dry sequences of the 1970s and 1980s revealed in the region by previous studies.
A Spatial Analysis Approach for Evaluating the Service Capability of Urban Greenways—A Case Study in Wuhan
Authors: Bai Junwen , Zhang Penglin , Du Juan , Li Zheng
Published: July 2017

A greenway is a low-speed road system built on high-level afforestation, and this system serves as a venue for sightseeing, relaxation, and exercise. In China, greenway planning and construction have been actively and successfully implemented to strengthen the construction of urban human settlements. However, a specific method has yet to be used to assess the service capability of urban greenways. On the basis of geographic information systems and geographical spatial data, we propose an approach to evaluate the overall service capability of urban greenways based on three different aspects. In the first aspect, a buffer-based service-level analysis method is applied to statistically analyze population and residential quarter areas within a greenway service coverage area. This aspect can also indicate the service level and scope of urban greenways. In the second aspect, minimum distance-based accessibility analysis method is utilized for the graduation statistics of residential quarter areas in different ranges of reach distance. This aspect can further reveal the service convenience of urban greenways. In the third aspect, a calculation model is built on the basis of regular grids, to analyze the value of comprehensive service capability in each grid, and to produce a spatial distribution map of the comprehensive service capability of urban greenways. This aspect can describe the service quality of urban greenways. The analysis results of these aspects can be integrated to identify service conditions in which an urban greenway is available to urban populations and residential zones, and to obtain the comprehensive service capability value of greenways. This approach can also emphasize the limitations of greenway construction, and thus help urban planners and decision-makers create optimized urban greenway designs.
The Application of REDOR NMR to Understand the Conformation of Epothilone B
Authors: Lee Jae-Ho , Kim Moon-Su , Lee Hyo , Lee Ihl-Young , Kim Hyun , Kim Nam , Lee SangGap , Seo Hwajeong , Paik Younkee
Published: July 2017

The structural information of small therapeutic compounds complexed in biological matrices is important for drug developments. However, structural studies on ligands bound to such a large and dynamic system as microtubules are still challenging. This article reports an application of the solid-state NMR technique to investigating the bioactive conformation of epothilone B, a microtubule stabilizing agent, whose analog ixabepilone was approved by the U.S. Food and Drug Administration (FDA) as an anticancer drug. First, an analog of epothilone B was designed and successfully synthesized with deuterium and fluorine labels while keeping the high potency of the drug; Second, a lyophilization protocol was developed to enhance the low sensitivity of solid-state NMR; Third, molecular dynamics information of microtubule-bound epothilone B was revealed by high-resolution NMR spectra in comparison to the non-bound epothilone B; Last, information for the macrolide conformation of microtubule-bound epothilone B was obtained from rotational-echo double-resonance (REDOR) NMR data, suggesting the X-ray crystal structure of the ligand in the P450epoK complex as a possible candidate for the conformation. Our results are important as the first demonstration of using REDOR for studying epothilones.
Inflammatory and Noninflammatory Itch: Implications in Pathophysiology-Directed Treatments
Authors: Wong Lai-San , Wu Tiffany , Lee Chih-Hung
Published: July 2017

Itch is the main chief complaint in patients visiting dermatologic clinics and has the ability to deeply impair life quality. Itch results from activation of cutaneous nerve endings by noxious stimuli such as inflammatory mediators, neurotransmitters and neuropeptides, causing itch signal transduction from peripheral skin, through the spinal cord and thalamus, to the brain cortex. Primarily noninflammatory diseases, such as uremic pruritus, cause itch through certain pruritogens in the skin. In inflammatory skin diseases, atopic dermatitis (AD) is the prototypic disease causing intensive itch by aberrant skin inflammation and epidermal barrier disruption. Recent understanding of disease susceptibility, severity markers, and mechanisms have helped to develop targeted therapy for itch in AD, including monoclonal antibodies against IL-4, IL-13, thymic stromal lymphopoietin (TSLP), IgE and IL-31. Promising effects have been observed in some of them. In this review, we summarized targeted therapies for inflammatory itch in AD and for managing abnormal itch transductions in other common itching skin diseases.
Ambient Assisted Living and Health-Related Outcomes—A Systematic Literature Review
Authors: Queirós Alexandra , Dias Ana , Silva Anabela , Rocha Nelson
Published: July 2017

The active ageing paradigm aims to contribute to the expectation of a long, autonomous, independent and healthy life. Ambient Assisted Living (AAL) promotes the development of technological solutions that might have a key role in not only the optimization of support services for older adults but also in the mitigation of their disabilities. This article presents a systematic literature review of how the impact of AAL technologies, products and services is being assessed in terms of its health-related outcomes. The main objective of this article is to contribute to the understanding of how state-of-the-art AAL solutions might influence the health conditions of older adults. The method used to conduct this systematic literature review followed the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The results show that the reviewed articles report not only the use of technological assessment instruments but also instruments to measure health-related outcomes such as quality of life.
I Can’t Program! Customizable Mobile Language-Learning Resources for Researchers and Practitioners
Authors: Barcomb Mike , Grimshaw Jennica , Cardoso Walcir
Published: July 2017

Combining insights from Activity Theory (Engeström, 2014), mobile-assisted language-learning (MALL) (Stockwell and Hubbard, 2013), and computer-assisted language learning (CALL) research (Chapelle, 2001), this paper proposes three levels of teacher involvement in the adaptation and/or creation of MALL resources to enhance learner interaction with the target language and potentially contribute to the field of learner-computer interactions. Specifically, this paper (1) proposes three levels of teacher involvement in MALL material creation, moving from easily adaptable pre-made materials (e.g., Duolingo) to customizable materials (e.g., Quizlet) and finally to teacher-created materials (e.g., Moodle); (2) demonstrates how these levels of design can be implemented in a MALL context to increase target language interaction according to Activity Theory (e.g., how teachers can incorporate gaming features into their online courses); and (3) concludes with recommendations as to how MALL “engineers” can work together to enhance the overall L2 learning experience and potentially collaborate in research and in the design of pedagogical materials. From a pedagogical standpoint, through these three levels of teacher involvement in material creation, teachers can extend the reach of their classrooms by mobilizing the target L2 environments, depending on their MALL/CALL proficiency and/or interests. This approach also invites second language acquisition scholars from a wide range of technological abilities to contribute to CALL research.
Structure and Photoluminescence Properties of Sm3+ Ion-Doped YInGe2O7 Phosphor
Authors: Shih Hung-Rung , Chang Yee-Shin
Published: July 2017

A new phosphor, Sm3+ ion-doped YInGe2O7, was synthesized using a planetary ball mill solid state reaction. The XRD patterns show that all of the peaks can be attributed to the monoclinic YInGe2O7 crystal structure when the Sm3+ ion concentration is increased up to 20 mol %. Under an excitation wavelength of 404 nm, the Sm3+ intra-4f transition appears in the emission spectrum including two stronger emission peaks located at 560–570 nm and 598 nm correspond to the 4G5/2 → 6H5/2 and 4G5/2 → 6H7/2 transitions, respectively, and another weak emission peak located at 645 nm is due to the 4G5/2 → 6H9/2 transition. The decay time decreases from 4.5 to 0.8 ms as Sm3+ ion concentrations increase from 1 to 20 mol %, and the decay mechanism of the 4G5/2 → 6H7/2 transition is a single decay component between Sm3+ ions only. The concentration quenching effect occurs when the Sm3+ ion concentration is higher than 3 mol %. The CIE color coordinate of Y0.97Sm0.03InGe2O7 phosphor is at x = 0.457 and y = 0.407, which is located in the orange-yellow light region.
Discovery of DNA Topoisomerase I Inhibitors with Low-Cytotoxicity Based on Virtual Screening from Natural Products
Authors: Xin Lan-Ting , Liu Lu , Shao Chang-Lun , Yu Ri-Lei , Chen Fang-Ling , Yue Shi-Jun , Wang Mei , Guo Zhong-Long , Fan Ya-Chu , Guan Hua-Shi , Wang Chang-Yun
Published: July 2017

Currently, DNA topoisomerase I (Topo I) inhibitors constitute a family of antitumor agents with demonstrated clinical effects on human malignancies. However, the clinical uses of these agents have been greatly limited due to their severe toxic effects. Therefore, it is urgent to find and develop novel low toxic Topo I inhibitors. In recent years, during our ongoing research on natural antitumor products, a collection of low cytotoxic or non-cytotoxic compounds with various structures were identified from marine invertebrates, plants, and their symbiotic microorganisms. In the present study, new Topo I inhibitors were discovered from low cytotoxic and non-cytotoxic natural products by virtual screening with docking simulations in combination with bioassay test. In total, eight potent Topo I inhibitors were found from 138 low cytotoxic or non-cytotoxic compounds from coral-derived fungi and plants. All of these Topo I inhibitors demonstrated activities against Topo I-mediated relaxation of supercoiled DNA at the concentrations of 5–100 µM. Notably, the flavonoids showed higher Topo I inhibitory activities than other compounds. These newly discovered Topo I inhibitors exhibited structurally diverse and could be considered as a good starting point for the development of new antitumor lead compounds.
Metal-Mediated Addition of N-Nucleophiles to Isocyanides: Mechanistic Aspects
Authors: Kuznetsov Maxim , Kukushkin Vadim
Published: July 2017

Despite the long history of the investigation of nucleophilic addition to metal-bound isocyanides, some important aspects of the reaction mechanism remain unclear even for the simplest systems. In this work, the addition of the sp3-N, sp2-N, and mixed sp2/sp3-N nucleophiles (i.e., HNMe2, HN=CPh2, and H2N–N=CPh2, respectively) to isocyanides C≡NR coordinated to the platinum(II) centers in the complexes cis-[Pt(C≡NCy)(2-pyz)(dppe)]+ (2-pyz = 2-pyrazyl, dmpe = Me2PCH2CH2PMe2) and cis-[PtCl2(C≡NXyl)(C≡NMe)] was studied in detail by theoretical (DFT) methods. The mechanism of these reactions is stepwise associative rather than concerted and it includes the addition of a nucleophile to the isocyanide C atom, deprotonation of the nucleophilic moiety in the resulting intermediate, and protonation of the isocyanide N atom to give the final product. The calculated activation energy (ΔG≠) of all reactions is in the range of 19.8–22.4 kcal/mol.
Therapeutic Delivery of Butyrylcholinesterase by Brain-Wide Viral Gene Transfer to Mice
Authors: Gao Yang , Geng Liyi , Chen Vicky , Brimijoin Stephen
Published: July 2017

Recent research shows that butyrylcholinesterase (BChE) is not simply a liver enzyme that detoxifies bioactive esters in food and medications. In fact, in pursuing other goals, we recently found that it has an equally important role in regulating the peptide hormone ghrelin and its impact on hunger, obesity, and emotions. Here, we present and examine means of manipulating brain BChE levels by viral gene transfer, either regionally or globally, to modulate ghrelin signaling for long-term therapeutic purposes and to set the stage for exploring the neurophysiological impact of such an intervention.
Combining NMR Spectroscopy and Chemometrics to Monitor Structural Features of Crude Hep-arin
Authors: Mauri Lucio , Marinozzi Maria , Mazzini Giulia , Kolinski Richard , Karfunkle Michael , Keire David , Guerrini Marco
Published: July 2017

Because of the complexity and global nature of the heparin supply chain, the control of heparin quality during manufacturing steps is essential to ensure the safety of the final active pharmaceutical ingredient (API). For this reason, there is a need to develop consistent analytical methods able to assess the quality of heparin early in production (i.e., as the crude heparin before it is purified to API under cGMP conditions). Although a number of analytical techniques have been applied to characterize heparin APIs, few of them have been applied for crude heparin structure and composition analyses. Here, to address this issue, NMR spectroscopy and chemometrics were applied to characterize 88 crude heparin samples. The samples were also analyzed by strong anion exchange HPLC (SAX-HPLC) as an orthogonal check of the purity levels of the crudes analyzed by NMR. The HPLC data showed that the chemometric analysis of the NMR data differentiated the samples based on their purity. These orthogonal approaches differentiated samples according their glycosaminoglycan (GAG) composition and their mono and disaccharide composition and structure for each GAG family (e.g., heparin/heparan, dermatan sulfate, and chondroitin sulfate A). Moreover, quantitative HSQC and multivariate analysis (PCA) were used to distinguish between crude heparin of different animal and tissue sources.
Use of Polycaprolactone Electrospun Nanofibers as a Coating for Poly(methyl methacrylate) Bone Cement
Authors: Khandaker Morshed , Riahinezhad Shahram , Jamadagni Harsha , Morris Tracy , Coles Alexis , Vaughan Melville
Published: July 2017

Poly(methyl methacrylate) (PMMA) bone cement has limited biocompatibility. Polycaprolactone (PCL) electrospun nanofiber (ENF) has many applications in the biomedical field due to its excellent biocompatibility and degradability. The effect of coating PCL ENF on the surface topography, biocompatibility, and mechanical strength of PMMA bone cement is not currently known. This study is based on the hypothesis that the PCL ENF coating on PMMA will increase PMMA roughness leading to increased biocompatibility without influencing its mechanical properties. This study prepared PMMA samples without and with the PCL ENF coating, which were named the control and ENF coated samples. This study determined the effects on the surface topography and cytocompatibility (osteoblast cell adhesion, proliferation, mineralization, and protein adsorption) properties of each group of PMMA samples. This study also determined the bending properties (strength, modulus, and maximum deflection at fracture) of each group of PMMA samples from an American Society of Testing Metal (ASTM) standard three-point bend test. This study found that the ENF coating on PMMA significantly improved the surface roughness and cytocompatibility properties of PMMA (p < 0.05). This study also found that the bending properties of ENF-coated PMMA samples were not significantly different when compared to those values of the control PMMA samples (p > 0.05). Therefore, the PCL ENF coating technique should be further investigated for its potential in clinical applications.
Eco-Friendly Acaricidal Effects of Nylon 66 Nanofibers via Grafted Clove Bud Oil-Loaded Capsules on House Dust Mites
Authors: Kim Joo , Kim Seong
Published: July 2017

Acaricidal nylon 66 fabrics (AN66Fs) grafted with clove oil-loaded microcapsules (COMCs) were developed against Dermatophagoides farina (D. gallinae). The average diameter was about 2.9 µm with a range of 100 nm–8.5 µm. COMCs carried clove oil loading of about 65 vol %. COMCs were chemically grafted to electrospun nylon nanofibers by the chemical reactions between –OH groups of COMCs and –COOH end groups of nylon fabrics to form ester linkages. AN66Fs had an effect on D. farinae depending on COMCs loadings. The increase in COMCs loading of AN66Fs from 5 to 15 wt % increased from 22% to 93% mortality against D. farinae within 72 h. However, AN66Fs containing over 20 wt % COMCs were more effective, showing up to 100% mortality within 24 h because the large amount of monoterpene alcohol, eugenol. This research suggests the use of clove oil and its major constituent eugenol as eco-friendly bioactive agents that can serve as a replacement for synthetic acaricides in controlling the population of D. farinae.
Sero-Surveillance of Lyssavirus Specific Antibodies in Nigerian Fruit Bats (Eidolon helvum)
Authors: Tyem Dinchi , Dogonyaro Banenat , Woma Timothy , Ngoepe Ernest , Sabeta Claude
Published: July 2017

The aetiological agent of rabies is a member of the Lyssavirus genus (Rhabdoviridae family, order Mononegavirales). The disease (rabies) is endemic in many parts of Asia and Africa and still remains an important public and veterinary health threat. In Nigeria, there is a dearth of information on the natural infection and/or exposure of bat species to lyssaviruses. Therefore, this study was undertaken to assess the prevalence of rabies virus (RABV) neutralizing antibodies in sera obtained from bats from the central Plateau and North-East Bauchi States in Nigeria. Two hundred serum samples were collected from Nigerian fruit bats from six different locations and tested for anti-RABV antibodies using a commercial blocking ELISA. Of the 200 bat serum samples collected, one batch consisting of 111 samples did not meet the validation criteria and hence was not included in the final analysis. Of the remaining 89, only three (3.4%) contained anti-lyssavirus antibodies, demonstrating a low prevalence of lyssavirus antibodies in the study population. In order to further understand the exposure of bat species to phylogroup II lyssaviruses (Lagos bat virus and Mokola virus), the same panel of samples will be tested for neutralizing antibodies to phylogroup II members, viruses that do not cross-neutralize with members of phylogroup I.
Non-Linear Stationary Solutions in Realistic Models for Analog Black-Hole Lasers
Authors: De Nova Juan
Published: July 2017

From both a theoretical and an experimental point of view, Bose–Einstein condensates are good candidates for studying gravitational analogues of black holes and black-hole lasers. In particular, a recent experiment has shown that a black-hole laser configuration can be created in the laboratory. However, the most considered theoretical models for analog black-hole lasers are quite difficult to implement experimentally. In order to fill this gap, we devote this work to present more realistic models for black-hole lasers. For that purpose, we first prove that, by symmetrically extending every black-hole configuration, one can obtain a black-hole laser configuration with an arbitrarily large supersonic region. Based on this result, we propose the use of an attractive square well and a double delta-barrier, which can be implemented using standard experimental tools, for studying black-hole lasers. We also compute the different stationary states of these setups, identifying the true ground state of the system and discussing the relation between the obtained solutions and the appearance of dynamical instabilities.
Switchable highly regioselective synthesis of 3,4-dihydroquinoxalin-2(1H)ones from o-phenylenediamines and aroylpyruvates
Authors: Dobiaš Juraj , Ondruš Marek , Addová Gabriela , Boháč Andrej
Published: July 2017

3-Acylmethylidene-3,4-dihydroquinoxalin-2(1H)-ones are compounds which possess a wide range of physical and pharmaceutical applications. These compounds can be easily prepared by cyclocondensation of o-phenylenediamines and aroylpyruvates. Unsymmetrically substituted o-phenylenediamines can be obtained form regioisomeric mixtures of 3,4-dihydroquinoxalin-2(1H)-ones. It is often quite difficult to get a pure regioisomer and determine its structure without controlling the reaction selectivity and exploitation of complex NMR techniques (HSQC, NOESY, HMBC). This article examines the regioselectivity of the cyclocondensation between six monosubstituted o-phenylenediamines (-OMe, -F, -Cl, -COOH, -CN, -NO2) and the derivatives of p-chlorobenzoylpyruvate (ester or acid) which we studied. Six regioisomeric 3,4-dihydroquinoxalin-2(1H)-one pairs were selectively prepared and characterised. Based on our experiences, a simplified methodology for determining the structure of the regioisomers was proposed. We developed two general and highly selective methodologies starting from the same o-phenylenediamines and activated 4-chlorobenzoylpyruvates (ester or acid) enabling switching of 3,4-dihydroquinoxalin-2(1H)-one regioselectivity in a predictable manner. For comparison, all regioselective cyclocondensations were performed with the same standardized conditions (DMF, rt, 3 days), differing only by the additives p-TsOH or HOBt/DIC (hydroxybenzotriazole/N,N’-diisopropylcarbodiimide). Both selected methods are simple, general and highly regioselective (72–97%). A mechanism for the regioselectivity was also proposed and discussed. This study can be used as a guide when choosing the most optimal reaction conditions for the synthesis of the desired 3,4-dihydroquinoxalin-2(1H)-one regioisomers with the best selectivity. The demonstrated methodologies in this article may also be applied to differently substituted 3,4-dihydroquinoxalin-2(1H)-ones in general, which could expand the synthetic impact of our results.
Acessibilidade em ambiente virtual de aprendizagem
Authors: Junior Albino Szesz , Silva Sani De Carvalho Rutz da , Vaz Maria Salete Marcon Gomes , Bittencourt Dênia Falcão de
Published: July 2017

O objetivo deste trabalho é expor as alterações focadas em acessibilidade virtual realizadas no ambiente virtual de aprendizagem da Universidade Estadual de Ponta Grossa. O trabalho foi realizado em três etapas: na primeira realizou-se estudos de acessibilidades em ambientes virtuais de aprendizagem, na segunda realizou-se alterações no ambiente Moodle versão 2.6 através da instalação de plug-ins e na terceira alterou-se o formato e layout do material disponibilizado. Os resultados apresentados demonstram as mudanças realizadas, tais como, a disponibilização da ferramenta de lupa, alto contraste e leitor de conteúdo, a possibilidade de tradução automática do português para libras, além da padronização de disciplinas. Conclui-se que as ações realizadas satisfazem o objetivo proposto, e destaca-se que encontrar uma interface adequada, com todos os aspectos de usabilidade e acessibilidade satisfeitos é um grande desafio.
As sequências didáticas como um procedimento de ensino para o gênero artigo de opinião
Authors: Mesquita Elisete Maria De Carvalho , Leão Cleonice De Moraes Evangelista , Souza Dalma Flávia Barros Guimarães de
Published: July 2017

Este artigo visa a apresentar uma proposta de trabalho para o artigo de opinião, que pode ser aplicada em salas de aula do Ensino Fundamental II. Para atingir o objetivo proposto, estabelecemos uma discussão a respeito de alguns temas que se relacionam com os interesses desta pesquisa, quais sejam: argumentação e ensino,  o gênero artigo de opinião e as sequências didáticas. Considerando a interação entre esses temas e, obedecendo aos pressupostos de Dolz, Noverraz e Schneuwly (2004), principalmente, elaboramos uma proposta para o ensino do gênero artigo de opinião, com o objetivo de levar o aluno a apropriar-se deste gênero e, consequentemente, aprimorar suas habilidades linguísticas e discursivas. Por meio dessa proposta, relacionamos a teoria com a prática pedagógica, no intuito de subsidiar o trabalho dos professores de língua portuguesa, quando o objetivo é ensinar os alunos a produzirem gêneros. Acreditamos que este trabalho possa diminuir a distância entre o que se ensina e o que o aluno utiliza em suas práticas sociais.
Poesia e crise em Jorge de Lima e Murilo Mendes
Authors: Assunção Sergio Carvalho
Published: July 2017

Este artigo visa abordar as poéticas de Murilo Mendes e Jorge de Lima sob a perspectiva da suprarrealidade e da busca da unidade com o sagrado, a partir da evidência de um estado de crise existencial e espiritual que se materializa ao nível do corpo e de suas respectivas linguagens poéticas.
O poema em prosa: a amorfia de uma modalidade lírica subutilizada no modernismo brasileiro
Authors: Teixeira Átila Silva Arruda
Published: July 2017

Nos textos críticos fundadores, a poesia lírica não é portadora de um estatuto que a iguala aos demais gêneros. Mesmo em períodos com maior normatização estética, não há como desconsiderar seu caráter proteiforme, ampliado desmesuradamente a partir da modernidade. Reverberando tal ampliação, surge o poema em prosa, modalidade da poesia lírica que ultrapassa a linha de delimitação que a distingue dos demais gêneros, encerrando já em seu nome um oximoro que se reflete nas tentativas críticas de sistematização. Consolidado em outras literaturas, essa modalidade é subutilizada no cânone poético brasileiro. Esboçado na obra As noites da virgem, de 1868, de Vitorino Palhares, começa de forma consciente com Raul Pompéia em Canções sem metro, de 1881. Já no modernismo, é esparsamente utilizado. Conclui-se neste artigo que o poema em prosa ocupa uma posição periférica – inclusive atualmente – na lírica brasileira devido a certo tom nefelibata que marcou a modalidade no nosso simbolismo, sendo substituído na função libertadora da lírica tradicional pelos versos livres.
Integrated Perinatal Mental Health Care
Authors: Kruper Abbey , Wichman Christina
Published: July 2017

This article outlines the development of an embedded multidisciplinary, perinatal mental health clinic comprised of psychiatry, psychology, and social work. The perinatal period is a critical time for women's mental health and is associated with an increased risk of mood disorders. Thus, obstetrics and gynecology (Ob-Gyn) physicians encounter a variety of patient mental health needs. Integrated care within Ob-Gyn clinics has demonstrated improvements in depression, adherence, and overall treatment satisfaction.This article outlines the development of an embedded multidisciplinary perinatal mental health clinic comprised of psychiatry, psychology, and social work. Common patient and physician barriers are discussed. Guidelines for implementing an integrated model include educating medical staff and patients, implementing screening measures, and ongoing collaboration among providers.

[
Psychiatr Ann
. 2017;47(7):368–373.]
The Physical Health of Patients with Psychiatric Disorders: What Is the Role of the Psychiatrist?
Authors: Reddy Geetha , Rado Jeffrey T.
Published: July 2017

People with chronic mental disorders, such as schizophrenia, experience excessive medical morbidity and mortality. This results from various patient, disease, and health-system factors. Among them is inadequate screening for and treatment of common medical conditions. There is a growing impetus for psychiatrists to play a larger role in the physical health of their patients. Clinical context, provider comfort and competence, and patient preference are all factors that must be considered. Psychiatrists' increasing involvement in managing the physical health issues of their patients is a key approach to reducing health disparities among people with chronic mental disorders.

[
Psychiatr Ann
. 2017;47(7):362–367.]
Premiers regards sur les sauvages (xvie siècle)
Authors: Duviols Jean-Paul
Published: July 2017

En se référant aux premiers témoignages des « visiteurs » européens sur les sauvages des Antilles et sur ceux du Brésil, on s’aperçoit que la remarque la plus fréquente est leur nudité inattendue, mais qu’ils ne manifestent pas une très grande surprise. Il en va de même pour le cannibalisme qui est décrit sans manifester trop d’émotion. Il semble que l’explication de cette attitude soit la tradition médiévale du « sauvage » européen, survivance d’un lointain passé. Quant à l’anthropophagie, elle est jugée moins « cruelle » que les supplices infligés aux vivants durant les guerres de religion. Elle n’en restera pas moins comme un signe iconographique du Nouveau Monde et comme un facile argument pour justifier leur domination.
Quelques Calibans cannibales entre historiographie, idéologie et littérature latino-américaine
Authors: Simorra Daniel Vives
Published: July 2017

Ce travail examine la figure de Caliban et de son double « anagrammatique » le « cannibale » tant dans le discours d’essai que dans d’autres formes littéraires. On s’efforce de les replacer dans le contexte des débats qui touchent aux rapports conflictuels entre historiographie et fiction. D’où la sauvagerie d’un Caliban-cannibale qui se situe à la croisée de l’histoire proprement dite et du fictionnel, de l’idéologie et de la rhétorique (tropes, symboles, métaphores). La discussion s’oriente notamment sur les formulations et les représentations de Caliban dans le domaine latino--américain (Rubén Darío, Roberto Fernández Retamar, Carlos Jáuregui…). On tente aussi de situer ces images du sauvage et du barbare, dans l’espace non occidental qui lui est propre, par rapport à certains courants de pensée récents – Edward Said, Homi Bhabha, Gayatri Spivak, critiques latino-américains de la subalternité-postcolonialité. Malgré le tour volontiers théorique et spéculatif des questions traitées, on ne peut négliger la question éminemment polémique de la réalité ou de la fabulation du « fait cannibale ». L’étude s’achève par une présentation, par force quelque peu sélective, du traitement que reçoivent Caliban et ses semblables, violents ou ensauvagés, dans le roman et la poésie latino-américaine depuis la fin du XIXe siècle.
El salvaje y territorios del salvajismo en El Espantapájaros de Ricardo Silva Romero
Authors: Medrano-Ollivier Carmen
Published: July 2017

En este artículo sobre la novela El Espantapájaros abordamos el concepto del salvaje y del salvajismo a partir del significado en el mundo contemporáneo de lo que sería ser civilizado. Según la definición de Tzvetan Todorov ser civilizado se define con relación a lo humano, a una manera particular de ser hombre. En este sentido, el salvaje es aquél que niega la humanidad del otro, que excluye al otro de la humanidad a través del uso extremo de la violencia como lo han hecho los actores de la violencia colombiana desde los años 60. Esta contraposición adquiere un mayor sentido a través del concepto del salvaje en la antigüedad griega y romana que nos lleva a pensar la frontera entre el salvaje y el civilizado como una frontera entre dos alteridades. En la novela, como en la historia de Colombia, se trata ante todo de una alteridad radical, política e ideológica. El análisis del personaje principal, el comandante Cigarra, jefe paramilitar al mando de la masacre narrada en El Espantapájaros, permite comprender la violencia más allá de su significación inmediata y/o de su racionalidad instrumental (política, ideológica). La violencia paramilitar que el Comandante Cigarra protagoniza a muerte, convertida en un fin destructivo en sí y asociada a un goce tanático, lejos de «ser absurda» o «sin sentido», constituye para él la única posibilidad en tanto que sujeto de construirse en principio de sentido de su propia subjetividad (Wieviorka).
Qu’entendre par jeu dans l’enseignement et l’apprentissage des langues : diversité des situations et des modalités d’apprentissage
Authors: Brougère Gilles
Published: July 2017

Derrière le vocable « jeu » on trouve des activités qui ont toutes les caractéristiques du jeu, d’autres qui sont des hybrides entre jeu et exercice scolaire, d’autres encore que l’on baptise « activités ludiques » et dont le lien avec le jeu est souvent ténu si ce n’est qu’il s’agit d’activités qui sont supposées moins ennuyeuses, plus amusantes. En relation avec l’apprentissage d’une langue, il peut s’agir de situations informelles autour d’un jeu en ligne ou d’autres formes de jeu ou de situations formelles, plus ou moins scolaires, où le jeu est proposé pour ses effets éducatifs (ou supposés tels) et non plus seulement dans une perspective de divertissement. Cet article tente de clarifier la question des enjeux du jeu dans l’enseignement et l’apprentissage d’une langue seconde en croisant l’analyse du jeu et celle de l’apprentissage.
L’introduction de jeux sérieux en cours de traduction
Authors: Popineau Joëlle
Published: July 2017

Enseigner la traduction à l’université s’appuie sur des théories traductionnelles. Cependant, lorsqu’il s’agit d’enseigner la traduction spécialisée, les théories classiques montrent leurs limites. Introduire des jeux sérieux permet d’intégrer la pratique du métier de traducteur dans le socle d’apprentissages, tout en introduisant de nouvelles théories traductionnelles.
PRINCÍPIOS E TRATAMENTOS ALTERNATIVOS DE LESÕES TENDÍNEAS EM CÃES
Authors: Olsson Débora Cristina , Pippi Ney
Published: July 2017

Esta revisão destaca a morfologia e pesquisas sobre tratamentos alternativos para lesões no tendão calcâneo de cães, seus processos de cicatrização através de mudanças em sua estrutura, composição e biomecânica. A inflamação excessiva é um fator principal subjacente à formação de aderências na superfície de reparo e afeta a regeneração da matriz no centro de reparo que limita a excursão do tendão e prejudica a cicatrização. Estudos revelaram que as terapias celulares provenientes de pesquisas com engenharia tecidual modulam a resposta dos fibroblastos tendinosos à inflamação induzida por macrófagos. Baseado nos tratamentos, a anatomia do desenvolvimento tendinoso e das vias mecânicas transdutivas torna-se reconhecido os esforços recentes da medicina veterinária para alternativas adjuvantes aos tendões feridos e para sugerir estratégias futuras potenciais para a intervenção terapêutica e engenharia de tecidos funcionais. Apesar da abundância de evidências clínicas sugerindo que os tratamentos atuais e estratégias de reabilitação para rupturas do tendão são necessários, questões significativas permanecem para elucidar completamente os mecanismos científicos básicos que governam lesão do tendão calcâneo, cura, tratamento e reabilitação. Nesta revisão, são abordados alguns aspectos anatômicos da reparação, uso de enxerto e terapia celular como acelerador de processos cicatriciais no tendão calcâneo de cães.
Cor triatriatum – Uma Revisão de Literatura
Authors: Araujo Camila Carneiro , Carvalho Ercília Maria , Nascimento Amanda Luiza , Santos Sheila Sousa , Correia Paula Priscila
Published: July 2017

O Cor triatriatum é uma anomalia congênita de ocorrência rara em cães. Nesta, identifica-se a presença de três átrios no coração, sendo denominado Cor triatriatum dexter quando há um átrio a mais do lado direito e Cor triatriatum sinister quando esta anomalia ocorre do lado esquerdo. A causa da doença ainda não está conhecida, mas é sabido que ocorre falhas na embriogênese do animal acometido por esta enfermidade. Os animais que possuem a doença apresentam sinais de insuficiência cardíaca direita ou esquerda. O diagnóstico é realizado por meio de exames complementares, dentre estes, se destaca o ecodopplercardiograma como método de escolha. O tratamento baseia-se na correção cirúrgica e/ou tratamento para a insuficiência cardíaca. Para evitar o surgimento desta anomalia, recomenda-se a castração destes animais, a não repetição do cruzamento que gerou este filhote, assim como, cruzamento consanguíneos.
Remote Sensed Land Surface Temperature Anomalies for Earthquake Prediction
Authors: Bellaoui Mebrouk , Hassini Abdelatif , Bouchouicha Kada
Published: July 2017

Thermal anomaly Detection prior to earthquake events has been widely confirmed by researchers over the past decade. In this paper, we use robust satellite technique approach (RST) on a collection of six years of MODIS satellite data, representing land surface temperature (LST) images to predict 21st May 2003 Boumerdès Algeria earthquake. The thermal anomalies results were compared with the ambient temperature variation measured in three meteorological stations of Algerian National Office of Meteorology (ONM) (DELLYS-AFIR, TIZI-OUZOU, and DAR-EL-BEIDA). The results confirm the importance of robust satellite technique as an approach highly effective for monitoring the earthquakes.
Mechanical Behavior of Stabilizing Materials Using Silicate Mineral Powder
Authors: Cho Jin Woo , Lee Ju Hyung , Choi Eun Kyeong , Kim Sung Wook
Published: July 2017

This study aims to develop eco-friendly materials that can reduce the high unit weight of carbonate cement, as typical ground improvement material, and the release of harmful substances. Silicate binder, which is an inorganic matter based on a silicate mineral, includes kaolin, illite and metakaolin. A silicate mineral is made into silicate binder through continuous weathering. Most clay minerals belong to this silicate binder. This study conducted a preliminary study on the strength properties of feldspar powder with high activity. A specimen was made using various silicate material sources such as feldspar, metakaolin, silica fume, illite, dolomite and silica stone. This study analyzed the uniaxial compressive strength according to the type and particle size of silicate binder. The analysis result showed that the uniaxial compressive strength of a specimen using feldspar powder as silicate binder was highest. In particular, the compressive strength of a specimen where silicate powder was added as binder was higher compared to normal cement. This means that feldspar powder with high activity can be utilized as an eco-friendly resource that can replace cement.
Evaluation of Uniaxial Tensile Behavior under Pulsed Current for Electrically Assisted Warm Forming of Light Weight Alloys
Authors: Song Jung Han , Jang Injea , Gwak Suh Yun , Bang Jun Ho , Kim Yong Bae , Lim Jung Sik , Lim Chang Yong , Seo Jong Duk
Published: July 2017

In this study, the electric current effects in the deformation of light weight alloys are investigated to improve the formability. To begin with, a test system is built up to carry out the tensile test with heavy electric current flowing through the specimen. The evolutions of the flow stresses and failure elongations were obtained using this test system. The thermal and athermal effect such as electro-plastic effect of metallic materials induced by high density current make significant reduction of the flow stress, which is beneficial to the forming process of less formable metal. From the uniaxial test results, pulse current-assisted deep drawing test were conducted. The experimental results demonstrate that electrically assisted warm forming provides lower energy consumption and higher efficiency.
Simulation of Mechanical Properties of Light-Burned Magnesium Oxide-Containing Concrete for Historical Dam Temperatures
Authors: Yang Yong Min , Li Zhao Heng , Zhang Tong Sheng , Yu Qi Jun
Published: July 2017

Previous studies showed that curing regime has a significant influence on mechanical properties of light-burned magnesium oxide (MgO) concrete. However, research has been limited mostly to constant-temperature studies, whereas dams manufactured from concrete exist in variable-temperature environments. In order to achieve material performance parameters that agree more closely with engineering practice, the development of mechanical properties of light-burned MgO concrete curing at constant temperature and simulated dam body temperature was studied. The compressive strength, elastic modulus and ultimate tensile strain of light-burned MgO concrete increased with the increase of curing temperature, MgO content and curing age. These constant-temperature properties were similar to those under simulated dam body temperature curing conditions. A comparison of experimental results of simulated dam body temperature curing and constant temperature curing showed that a thermostatic curing system was suitable for calculating the laws of mechanics development for dam concrete.
Treatment of V2O5/TiO2 by Non-Thermal Plasma: Changes in Surface Characters and Mercury Oxidation Activity
Authors: Liu Lu , Zheng Cheng Hang , Gao Xiang
Published: July 2017

The technology for mercury removal in coal-fired power plant is still under development. In the flue gas, elemental mercury is the main component of mercury, and is hard to be removed due to its high volatility and low solubility. So converting Hg0 to Hg2+ in or ahead of the FGD is significant to enhance mercury removal. In this work, plasma treatment method was used to prepare V2O5/TiO2 catalysts for effectively oxidation of Hg0. Plasma treatment of V2O5/TiO2 resulted in the improvement of mercury oxidation activity. The Hg0 oxidation efficiency of the catalysts treated by plasma is over 82% at 300 °C, which is about 30% higher than that of the untreated catalyst. The catalysts were characterized using SEM, BET and EPR. SEM results indicated that plasma treatment can create cracks and small particles on simple surface, however, calcinations cause sintering and agglomeration. The superior catalytic performance is mainly attributed to the formation of particles attached to the catalyst surface, the higher amount of V4+ ions and vacancies on the catalyst surface.
Influence of Metakaolin, Fly Ash and Nano Silica on Mechanical and Durability Properties of Concrete
Authors: Kumar Rabinder , Mohd Yaseen Airil Yasreen B. , Shafiq Nasir , Jalal Asif
Published: July 2017

Concrete is widely used construction material for the development of built environment which consumes huge amount of cement, around 4.3 billion metric ton all over the world. Reinforced concrete construction exposed to harsh environment such as chloride bound air causes deterioration in concrete through its pore structure by corroding the steel bar. The use of pozzolanic material i.e. metakaolin (MK), fly ash (FA), silica fume (SF), nano silica (NS) can be used as partially cement replacing material which not only reduces the pores in concrete but improves the mechanical, durability properties and microstructure of concrete. This paper reviews various transport mechanisms involved in ingress of deleterious material and incorporation of MK, FA and NS in concrete and their effects on concrete mechanical and durability properties. However, the research work provides an extended approach to evaluate combine effect using MK, FA, and NS and to produce a concrete with more refined pore structure for aggressive environment.
Characterisation of {P4, K ̅3}-free graphs
Authors: Klem Estiaan M. , Ter Horst Sanne
Published: July 2017

No abstract available.
Inter- and intra-observer variability of ultrasonographic arm muscle thickness measurement by critical care physicians
Authors: Hadda V , Kumar R , Dhungana A , Khan MA , Madan K , Khilnani GC
Published: July 2017

Purpose:

The aim of this study was to assess inter- and intra-observer variability of arm muscle thickness measured by critical care physicians using bedside ultrasonography (USG).

Methodology:

This prospective study included twenty patients admitted with sepsis. Three measurements of thickness of right arm muscles of each patient using B-mode USG were taken by two critical care fellows, independently. Intra- and inter-observer reliability was tested using intraclass correlation coefficient (ICC).

Results:

The mean 1st, 2nd, and 3rd measurements of muscle thickness recorded by observer 1 and 2 were 23.620 (±4.171) versus 23.840 (±3.849) mm, 23.235 (±3.620) versus 23.625 (±4.062) mm, and 24.125 (±4.098) versus 23.965 (±3.651) mm, respectively. The average muscle thickness measured by first and second observer was 23.660 (±3.834) mm and 23.810 (±3.674) mm, respectively. ICC for intra-observer variability for observer 1 and 2 was 0.964 (95% confidence interval [CI] 0.924–0.985) and 0.949 (95% CI 0.892–0.978), respectively. ICC for inter-observer variability was 0.995 (95% CI 0.988–0.998).

Conclusions:

USG is a reliable tool for assessment of arm muscle thickness by critical care physicians.
Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
Authors: Gupta A , Reddy GK , Goyal M , Kasaragadda MR
Published: July 2017

Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with a poor prognosis despite intensive chemotherapy. Meticulous bone marrow examination in such a scenario may point towards the presence of t(8;16) and help clinicians take a well-informed clinical decision.
Endoscopic carpal tunnel decompression: Comparison of mid- and long-term outcomes of 30 endoscopic and 30 standard procedure carpal tunnel decompression operations
Authors: Eroglu Umit , Ozgural Onur , Yakar Fatih , Kahiloğulları Gökmen
Published: July 2017

Background: Carpal tunnel syndrome is the most frequently seen trap neuropathy leads to pain, paresis, and weakness of hands. Methods: Totally, 60 patients who underwent endoscopic or standard CTS surgery in İbni Sina Hospital, Medical Faculty of Ankara university in the period of 2009 and 2012 were enrolled in this prospective study. Results: During 36 months, 60 patients had undergone hand surgery. Totally, 14 male and 46 female patients of this serial had an average age of 51.24 (22-74) years. A number of 26 patients (43%) had left and 34 had (57%) right hand surgery. Complete relief of nocturnal paresis and pain has been shown in the 6th, 12th, and 24th month analyses of endoscopic surgery group results. Two patients in open surgery group underwent second operation due to relapse. The patients in the endoscopic group reported higher satisfaction cosmetically. Conclusion: Endoscopic carpal tunnel syndrome treatment is alternative and considerable option against standard open methods and due to low morbidity rates its performance is highly prevalent in recent years.