bluuebunny/crossref_metadata_2025 huggingface dataset:
Cost-effectiveness of edaravone dexborneol versus dl-3-n-butylphthalide for the treatment of acute ischemic stroke: a Chinese health care perspective
Authors: Li Jianchun , Cao Weihan , Zhao Fei , Jin Pengfei
Published: October 2023

Background: Edaravone dexborneol and dl-3-n-butylphthalide are two innovative brain cytoprotective drugs from China that have been approved and widely prescribed for acute ischemic stroke, and the cost of the two drugs are partially paid by the Chinese medical insurance system. This study aimed to investigate and compare the cost-effectiveness of edaravone dexborneol versus dl-3-n-butylphthalide for acute ischemic stroke from the Chinese healthcare system’s perspective.
Methods: A model combining a short-term decision tree model with 90 days and a long-term Markov model with a life-time horizon (40 years) was developed to simulate the cost-effectiveness of edaravone dexborneol versus dl-3-n-butylphthalide for acute ischemic stroke over a lifetime horizon. Since the absence of a head-to-head clinical comparison of two therapies, an unanchored matching-adjusted indirect comparison (MAIC) was conducted by adjusting the patient characteristics using individual patient data from pivotal phase III trial of edaravone dexborneol and published aggregated data of dl-3-n-butylphthalide. Health outcomes were measured in quality-adjusted life years (QALYs). Utilities and costs (Chinese Yuan, CNY) were derived from publications and open-access database. One-way and probabilistic sensitivity analyses were performed to evaluate the robustness of results.
Results: Compared with patients in dl-3-n-butylphthalide arm, edaravone dexborneol arm was found to be cost-effective in 90 days and highly cost-effective as the study horizons extended. With a similar direct medical cost, patients in edaravone dexborneol arm slightly gained an additional 0.1615 QALYs in life-time. In the long term (40 years), patients in edaravone dexborneol arm and dl-3-n-butylphthalide arm yielded 8.0351 and 7.8736 QALYs with the overall direct medical cost of CNY 29,185.23 and CNY 29,940.28, respectively. The one-way sensitivity analysis suggested that the incremental cost-effectiveness ratio was most sensitive to the price of edaravone dexborneol and dl-3-n-butylphthalide.
Conclusion: Edaravone dexborneol is a cost-effective alternative compared with dl-3-n-butylphthalide for acute ischemic stroke patients in current medical setting of China.
Microparticles from ISR patients participate in vascular intimal hyperplasia by promoting oxidative stress, inflammation and adhesion through ERK and P38 pathways
Authors: Han Wen-Qi , Zhang Wei , Li Zhe , Wang Qun-Rang , Wu HaoYu , Liu Xin-Hong , Yang Yu-Juan , Cheng Gong , Chang Feng-Jun
Published: October 2023

Objectives: Percutaneous coronary intervention (PCI) has become the most commonly used vascular reconstruction method for coronary atherosclerotic heart disease (CHD). However, In-stent restenosis (ISR) seriously affects the prognosis of PCI. Vascular intimal hyperplasia play key roles in ISR. Whether circulating microparticles (MPs) from ISR patients, which cause oxidative stress, inflammation and adhesion of vascular, participate in endothelial dysfunction and vascular intimal hyperplasia remains unclear.
Methods: MPs were obtained from both healthy subjects (n=20) and coronary heart disease patients with (n=33) or without (n=33) ISR 1year after PCI. After testing MPs origins by flow cytometry. Affect of MPs (with or without inhibitor of mitogen activated protein kinase) on proliferation and migration , expression of Extracellular signal-related kinase (ERK), p38 mitogen activated protein kinase (P38) and c-Jun N-terminal kinases (JNK), generation of intercellular cell adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1) in human coronary artery smooth muscle cells (HCASMCs) were determined.
Results: Although MPs increased in patients with or without ISR compared with healthy subjects, there were no difference between patients with or without ISR in MPs concentration. Flow cytometry showed that both endothelial derived MPs (EMP) and platelet-derived MP (PMP) ratio expanded in patient group. MPs from patients without ISR stimulate HCASMCs proliferation and migration (which can be blocked partly by PD98059), increased phosphorylation of ERK and P38,but not JNK; increased ICAM-1 and VCAM-1 generation in HCASMCs (which can be blocked by SB20358 but not SP600125). All of these effects were strengthened by MPs from patients with ISR.
Conclusions: MPs from ISR participate in vascular intimal hyperplasia, which play a key roles in ISR, by stimulating proliferation and migration, promoting oxidative stress, inflammation and adhesion through ERK and P38 pathway in HCASMCs. This may indicated a potential therapeutic target for ISR.
Investigating the Viability of Micro-Level Wind Generation
Authors: O'Sullivan Sean
Published: October 2023

This study investigates the viability of micro-level wind generation in addressing the current energy and cost of living crisis through a two-fold approach: surveying public opinion and conducting experimental analysis on turbine rotor design and orientation. Initially, a survey was conducted among parents, staff, and students at my school to gauge perceptions regarding climate change, the electricity crisis, and micro-level wind generation. The survey revealed a significant concern about the initial cost of wind energy generation, though a substantial percentage of respondents showed interest in installing wind turbines, especially if supported by government grants.
Following the survey, 16 wind turbine rotors, 4 Motor Housing Assemblies, and 2 Arduino Data Capture Boards were designed, 3D printed, and utilised in seven experiments. Two tests were conducted in a wind tunnel at the University of Limerick under laminar airflow conditions, and five were carried out outdoors under turbulent airflow conditions, at comparable recorded wind speeds. Energy generation data was collected using an Arduino Uno, converted to mV using an ADC, and recorded alongside corresponding wind speeds for accurate analysis. This data enabled a performance comparison among all tested rotors under varying conditions, highlighting the rotor design with the highest energy output. A comparison was also made with a commonly used wind turbine rotor design, revealing an overall performance increase.
Furthermore, a commercially available 500W wind turbine was tested to estimate its annual energy generation. The findings from the rotor design experiments were then applied to gauge how these designs could enhance total efficiency and translate into cost savings. This mixed-method study, engaging 169 survey respondents, first sought to understand public opinion before moving onto an experimental investigation into rotor design efficiency. The results were then applied to a commercially available wind turbine to translate findings into potential cost savings.
Interestingly, during this research I identified a Scimitar convex-curved-bladed HAWT variation which consistently outperformed "traditional"-straight-bladed HAWT variations by an average of 20% increased generation in all conditions.
Direct comparisons and correlations were drawn with other studies investigating blade design and orientation, aligning the collected data with existing research while providing a new lens on enhancing micro-level wind generation efficiency.
Response of Treatment-Naive Brain Metastases to Stereotactic Radiosurgery
Authors: Ene Chibawanye , Faraj Christina Abi , Beckham Thomas , Weinberg Jeffrey S. , Andersen Clark , Haider Ali , Rao Ganesh , Ferguson Sherise , Heimberger Amy , McCutcheon Ian , Prabhu Sujit , Wang Chenyang , Ghia Amol , McGovern Susan , Chung Caroline , McAleer Mary , Tom Martin , Perni Subha , Swanson Todd , Yeboa Debra , Briere Tina , Lang Frederick , Li Jing , Suki Dima , Fuller Gregory , Huse Jason , Sawaya Raymond
Published: October 2023

With improvements in survival for patients with metastatic cancer, long-term local control of brain metastases has become an increasingly important clinical priority. While consensus guidelines recommend surgery followed by stereotactic radiosurgery (SRS) for lesions >3cm, smaller lesions (≤3cm) undergo SRS alone with variable responses. To determine factors influencing this variable response to SRS, we analyzed outcomes of brain metastases ≤3cm diameter in patients with no prior systemic therapy treated with frame-based single-fraction SRS. Following SRS, 294/1739 treated lesions demonstrated MRI findings concerning for local treatment failure (LTF), of which 228 /1739 (13%) demonstrated LTF and 66/1739 (3.7%) had an adverse radiation effect. Multivariate analysis demonstrated tumor size (>2cm) and melanoma histology were associated with higher LTF rates. Brain metastases ≤3cm are not uniformly responsive to SRS. Formal guidelines incorporating tumor size and histology are needed for determining whether to treat brain metastasis ≤3cm with SRS alone or surgery and SRS.
Object Sorting Based on Size and Colour Detection Using Arduino
Authors: C ODO AMOS , A.mahesh  , Ganesh P.H.V. , Na.Manikanta  , Teja S.L. Ravi
Published: October 2023

Automation has become the primary requirement for almost all the businesses. The accuracy and speed with which a machine performs a task is higher when compared to that of humans. In most of the industries major activities involve measurement, cutting and sorting. Sorting can be done based on size, shape, color and quality etc. The sorting will be done based on quality in our project. And quality is analyzed based on the object size and color. In the project we developed a system for sorting objects, the gear motors used to rotate the conveyor belt. IR sensor modules is used to detect the product movement on the conveyor belt, color sensor is Used detect color of an object and sends the signal to controller. The IR sensors sense the size of the object and send the high or low values to the controller and as per the size the microcontroller controls the servo motor and shifts the object to its destination. The LCD interfaced with the controller is used to indicate number of color objects.
Cardiac injuries in cerebrovascular accidents and their relationship to age, gender, and risk factors (high arterial
pressure, diabetes, smoking)
Authors: theeb Hasan Mahdi , Alhussein Yazan Hamdi , Chamieh Marwan
Published: October 2023

Introduction:
The importance of the research lies in that it sheds light on an important medical issue, which is the repercussions of various types of neurovascular accidents on the heart muscle through their effect on the movement, rhythm, and perfusion of the muscle and the subsequent heart diseases and disorders, and linking them to several factors such as gender, high arterial tension, and other factors in order to reduce We hope that the research will have a positive impact on the health of patients and on society as a whole.
Methods:
A COHORT study was conducted in Damascus Hospital in the Syrian Arab Republic in the city of Damascus from February to August 2023, reviewing patient records from 2015.
Results:
We studied five variables for the sample members, gender, age, habits, high blood pressure, and diabetes. Of the 429 patients who had a cerebrovascular accident who participated in the experiment, 53.8% were men and 46.2% were women. The majority group was in the age group of 61- 80 years with an average age of 64. The percentage of smokers out of the total sample does not exceed 40%. 79% of patients suffered from high blood pressure and 51% suffered from diabetes.
Let us then move on to the most important element in our study, which is heart disease in patients. The results were as follows:
46.3% of patients had suffered from myocardial infarction, and 72% of patients had valve problems. By searching for the presence of valvular calcifications, the largest percentage did not suffer from valvular calcification, at 76.2%.
Arrhythmia disorders: 64.3% of patients suffered from arrhythmia, and atrial fibrillation was dominant in 77% of the total cases, and 28.3% of patients suffered from ventricular contractions. Then we moved to the case of thickening of the heart walls with echo to find that the largest percentage did not suffer from this disease or from Pericardial injury: When searching for a case of cardiac arrest, only 16% of those who suffered from sudden cardiac arrest without knowing or mentioning the reasons. Then we found the relationship between heart disease and the study variables.
Conclusion:
Giving cardiac complications after the aforementioned strokes special importance in terms of diagnosis and early detection contributes effectively to preserving the patient’s life while reducing as much as possible the consequences that the injury sometimes leaves. Therefore, we praise the importance of early examination when cardiac signs and symptoms appear in patients in order to reduce the major impact. for these diseases.
Understanding the behavior of mild steel in sodium hydroxide: a biomass corrosion mitigation approach
Authors: Abraham Ojo Friday , Ezekiel Makinde Yinka , Oloruntoba Toyin
Published: October 2023

Aquatic plant biomasses offer the chance to utilize their undesirable organic matter, which disrupts the environment, as environmentally friendly corrosion inhibitors. The corrosion inhibition of mild steel extracts of water hyacinth (Eichhornia crassipes) was synthesized and evaluated. Electrochemical analysis via potentiodynamic polarization technique and gravimetric methodology was used to study the inhibitive effect, followed by optical micrographic evaluation. The inhibitory efficiency of the plant extract was improved by raising the concentration of the aqueous extracts. The water hyacinth had a linear relationship of increasing concentration with the reduction in corrosion rate. The optical micrographs further support less corrosion pitting at high inhibitor concentrations. Extraction method, temperature, and extract dosage were the three criteria examined. Ambient temperature and plant extract dose concentration were ideal circumstances, mainly when high-temperature digestion for extraction was used. Utilizing the optical microscopy (OM) technique, the efficiency of the examined bio-based inhibitor was also confirmed.
Le changement du lieu de résidence de l'enfant par l'autorité de protection de l'enfant
Authors: Vaerini Micaela
Published: October 2023

Le droit suisse prévoit que l'autorité de protection de l'enfant peut, à certaines conditions, autoriser le changement du lieu de résidence d'un enfant à l'étranger malgré l'opposition d'un parent détenteur de l'autorité parentale. L'objet de cette contribution est de présenter les lois applicables en Suisse en cas de changement de lieu de résidence d'un enfant et d'analyser les conséquences de la récente jurisprudence européenne (Roth c. Suisse et Plazzi c. Suisse) dans la pratique des autorités de protection.

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Die Kindesschutzbehörde kann unter bestimmten Bedingungen den Wechsel des Aufenthaltsortes eines Kindes ins Ausland genehmigen, auch wenn das sorgeberechtigte Elternteil nicht einverstanden ist. Dieser Beitrag stellt die in der Schweiz geltenden Regelung vor und analysiert vor diesem Hintergrund die Auswirkungen der der jüngsten Rechtsprechung des Europäischen Gerichtshof für Menschenrechte (Roth c. Schweiz und Plazzi c. Schweiz) auf die Praxis der Kindesschutzbehörden.
Analysis on mechanical and microstructural properties of electrodeposited Ni-TiN-AlN/Si3N4 composite coatings
Authors: Budi Esmar , Indrasari Widyaningrum , Sugihartono Iwan , Prayitno Teguh Budi , Nasbey Hadi , Fahdiran Riser , Rahman Md. Nizam Abd
Published: October 2023

The parameter such as reinforced particles plays a role in controlling the microstructure and eventually influences the mechanical properties of the composite coating. The microstructure strength of composite coating come from phase combination of the matrix and its reinforcement. This study described the effect of the electrodeposition process parameters of Si3N4 particle concentration on the Ni-TiN-AlN/Si3N4 composite coatings. Therefore, the experiment was performed by varying Si3N4 particles concentration in range of 0.2, 0.4 and 0.6 g/L in electrodeposition process. The coating morphology and crystal structure were characterized by mean of Scanning Electron Microscopy (SEM) and X-Ray Diffraction (XRD), respectively while the coating microhardness was tested by using Vickers hardness test. The calcultations were performed to analyze the coating stress from XRD data and presented its relation with the coating microhardness. The analysis results displayed that the uniform surface morphology of composite with the evolution of nitride particle aggregation was observed at various S3N4 particles concentration. In general, the uniformity morphology was due to the refinement of Ni crystallite size. The crystal structure was noticed prominently by Ni, TiN and AlN grains while Si3N4 grain was not observed due to its amorphous nature. In general, the increase of composite microhardness, as increasing Si3N4 concentration was attributed by the reducing Ni crystallite size lead to the increase of coating residual stress.
Development of adaptive control system for technological facility of primary oil refining
Authors: Safarova Aygun , Damirova Javida , Huseynov Ismayil
Published: October 2023

As it is known, primary oil processing facilities are designed for the production of light-colored oil products and various oil fractions that meet modern requirements with their quality. The main equipment of these technological facilities are rectification columns operating under atmospheric and vacuum conditions, which perform the decomposition of crude oil and fuel oil into various product fractions. Generally, the quality indicators of product fractions produced in these columns are provided by stabilizing the temperature modes at certain points (plates) of these or rectification columns by regulating the irrigation consumption supplied to those plates.

It should be noted that currently, in accordance with the requirements of the time, the design and development of new control systems that can adequately respond to more dynamic and variable external and internal stimulating influences for complex oil refining technological facilities is one of the main problems facing the automatic control theory. The paper is dedicated to the issue of developing a new automated control system that can provide the required accuracy in terms of quality management. As an adaptive control system, the purpose of such systems is to compensate in time for disturbance influences in the technological devices and to ensure the production of oil products with stable quality indicators, regardless of these influences. The purpose of study is to develop a control system that can meet the given requirements and ensure the produced products with relatively stable quality indicators, regardless of the controlled and uncontrolled exciting effects affecting the oil refinery technological complex.

The principle of operation of this system is based not only on the compensation of disturbance influences but also on the calculation of new operation strategies depending on these effects. The development of new automated control system that is able to provide the necessary accuracy of quality control in the lack of information is relevant
Management of fungicides can affect resilience of cultivars to foliar diseases in oats
Authors: Pereira Laura Mensch , Silva José Antonio Gonzalez da , Carvalho Ivan Ricardo , Colet Christiane de Fátima , Fraga Denize da Rosa , Fachinetto Juliana Maria , Alessi Odenis , Basso Natiane Carolina Ferrari , Peter Cibele Luisa , Babeski Cristhian Milbradt , Zardin Natália Guiotto , Heusner Lisa Brönstrup
Published: October 2023

The entry and progression of oat foliar diseases affect yield potential, requiring a combination of genetic resistance and management technologies. The objective of the study is implementing a management system to reduce the use of fungicide in oats by the anticipation of the application and a longer interval from the last application to the grain harvest, together with the identification of cultivars that are more resilient to disease. The study was developed in 2018 and 2019, in soil of type Typical Dystroferric Red Latosol and Cfa (humid subtropical) climate, in Augusto Pestana, RS, Brazil. The experimental design was randomized blocks with three replications in a 23 x 5 factorial, for 23 oat cultivars and 5 conditions of fungicide use: control (no application); one application 60 days after emergence (DAE); two applications at 60 and 75 DAE; three applications at 60, 75 and 90 DAE and four applications at 60, 75, 90 and 105 DAE, with measurement of grain productivity. In oat cultivation, the early and sequential application of fungicide at 60, 75 and 90 days after emergence guarantees satisfactory productivity with a long interval from the last application to harvest for greater food security. The cultivars URS Altiva and IPR Artemis show resilience in the presence of foliar diseases in the absence and reduced use of fungicide, facilitating the transition between conventional and agroecological agriculture in oat cultivation
Effect of geographical origin on yield and secondary metabolite content of extracts of Moroccan Juniperus thurifera
Authors: Benhssaine Khalid , Aabdousse Jamal , Salim Nora , Oussif Ilias , Ramchoun M’hamed , Elhabty Mohamed , Abbas Younes , Berrougui Hicham
Published: October 2023

The thuriferous juniper (Juniperus thurifera) is an important species in the Mediterranean region due to its ecological and economic values. It plays a significant role in preventing soil erosion and desertification, as well as being used in traditional medicine and as a source of essential oils for various industries. In addition, its extracts are considered as a source of bioactive compounds with various pharmacological activities, such as antioxidant, anti-inflammatory and antimicrobial effects. However in Morocco, it is considered as one of the undervalued and least preserved species. Its stands continue to be vigorously degraded. The present work aims to study the effect of the origin on the yield, the phenolic compounds, flavonoids and tannins contents and the antioxidant activity of the leaves extracts of this species. In order to accomplish this study, we carried out the extraction by soxhlet from the leaves of J. thurifera, coming from three geographical origins, using two solvents (hexane and ethanol). Then the dosage of different compounds (polyphenols, flavonoids and condensed tannins) and the evaluation of the antioxidant activity were carried out. The results show a significant variability between the samples coming from three different biogeographical zones, namely: the Eastern, Central and Western High Atlas in terms of yield and levels of polyphenols, flavonoids and condensed tannins. This allowed to demonstrate the effect of geographical origin and the interaction between environmental conditions and genotype on the production of secondary metabolites. In fact, we found that the Midelt population has a good yield in ethanolic extracts (9.41% ± 0.59) and hexane 6.57% ± 0.29. Furthermore, the El Haouz population is the richest in polyphenols in ethanolic extracts (191.30 ± 4.27 mg GAE /g Extract), as well as it has an important reducing potential (IC50 = 0.98 ± 0.05 mg/ml). These results can be exploited as bioindicators in all programs of valorization and conservation of Moroccan Juniperus thurifera
Working conditions and values of average annual effective doses for nondestructive testing operators in the Russian Federation and abroad
Authors: Bazhin S. Yu. , Shleenkova E. N. , Bogatyreva V. Yu.
Published: October 2023

The review presents description of the work and the main provisions on the working conditions for nondestructive testing operators from the standpoint of the system for ensuring radiation safety and radiation control. The values of the average annual effective doses of flaw detectorists in the Russian Federation and abroad are indicated. Official sources of information on doses in the Russian Federation and in the world, obtained from the results of individual dosimetric monitoring, were selected for presentation. The data of our own measurements were not included in this review. The difference in the name of the specialty of the studied group of personnel in Russian and English and the difference in the processing of primary measuring information in domestic and foreign sources of information are taken into account. The relevance of the need to resolve the issues of radiation safety and radiation monitoring of personnel involved in nondestructive testing is demonstrated, due to the fact that in the Russian Federation there are regulatory and methodological documents affecting the organization and conduct of individual dosimetric monitoring of personnel in the medical field and the nuclear industry, but they do not include personnel conducting nondestructive testing. Therefore, individual dosimetric control for nondestructive testing operators is carried out by accredited laboratories in accordance with the provisions of Methodical guidelines 2.6.1.3015-12.“Organization and management of individual dosimetry of medical staff”, i.e. without taking into account the exposure scenarios for personnel involved in nondestructive testing and the specifics of it work. The doses estimated in this way are included in the regional and federal databanks of personnel exposure doses. When entering dose values into data banks, there is no division of personnel into the personnel performing nondestructive testing in stationary and nonstationary conditions, therefore, the doses of personnel performing various types of nondestructive testing are averaged.
Development Of Webtoon-Based Comic Learning Media On Human Respiratory System Topic For Class VIII Middle School
Authors: Nur Muhammad Rizqi , Narulita Erlia , Nuha Ulin
Published: October 2023

Research on the development of Webtoon-based comic learning media on the material of the human respiratory system to increase the learning motivation of grade VIII junior high school students aims to determine whether there is a significant influence on student motivation after the application of the media developed by the researcher. Media development used the ADDIE model RD strategy, while to determine the effect on student motivation, the ARCS motivational questionnaire (Attention, Relevance, Confidence and Satisfaction) was used and then analyzed using the normality test and Paired Sample t-Test. The results of the study showed that there was an increase in the average value of motivation from before and after the application of the developed media, so that it can be stated that the developed media has a significant influence on the learning motivation of Grade VIII junior high school students.
Availability and Utilisation of Science Laboratory Facilities on Science Teacher-Trainees’ Pedagogical Content Knowledge in Science
Authors: Anane Nelson Mandela
Published: October 2023

This study assessed final-year science teacher-trainee perceptions of the impact of the availability and utilization of laboratory facilities on science students' pedagogical content knowledge (PCK) in science at Accra and Ada Colleges of Education. This research was motivated by an initial study that stated that the majority of junior high school science teachers were unable to teach science effectively so it was easier for students to understand. This research used a quantitative approach with a cross-sectional descriptive survey design involving 62 intern teachers, 15 science tutors, and two school principals. The research instrument (tutor and teacher questionnaire) was declared suitable for use after a slight revision with the Validity and Reliability scores of 0.84 and 0.86. The research revealed that final-year science teacher candidates at the Accra College of Education were of the opinion that the availability and utilization of laboratory facilities had a moderate but neutral impact on PCK in science, in contrast to the results of research by science teachers at Ada College which stated that the availability and use of Laboratory facilities have a high and positive impact on PCK Science. It is recommended that science tutors engage science trainee teachers in efficient hands-on activities, and also focus on on-campus and off-campus practicums to develop the training of PCK science trainee teachers.
Elsőéves egyetemisták pénzügyi tudása és attitűdje
Authors: Prégler Krisztina , Kovács Tamás
Published: October 2023

A pénzügyi kultúrával, műveltséggel kapcsolatos problémák jól ismertek, számos nemzetközi és hazai kutatás alátámasztotta, hogy mind a felnőtteknél, mind a fiataloknál lenne még hová fejlődni. Köztudott, hogy az oktatásnak és a nevelésnek a szerepe e területen szintén rendkívül fontos. A 2010-es években Magyarországon is elindult a pénzügyi edukáció különböző szereplőkkel és módszerekkel. Tanulmányunk az elsőéves egyetemisták pénzügyi tudására és attitűdjére fókuszál. Online kérdőívvel felsőoktatási szakképzésre (FOKSZ) vagy alapképzésre (BA) 2022 szeptemberére bekerülő elsőéves diákok általános pénzügyi tudását, magatartását, véleményét és befolyásoló tényezőit vizsgáltuk. Az adatokkal kereszttábla-elemzéseket végeztünk, az összefüggések mérésére Pearson-féle χ2 próbát alkalmaztunk. A kutatás tulajdonképpen egy 2021-es vizsgálatnak a folytatását és tovább gondolását jelenti, így összehasonlító elemzésre is sor került a tanulmányban. A válaszadók pénzügyek iránti érdeklődése közepes, a pénzügyi aktualitások iránti figyelem függ a nemtől. Tudáspróbánkon a hallgatók 3/5-e rossz eredményt ért el. Megerősítve más kutatók javaslatait, fontosnak tartjuk a pénzügyi ismeretek oktatását minden középszintű oktatási intézményben, továbbá célszerű lenne a különböző edukációs programok és versenyek számának és hatékonyságának növelése.
FEATURES OF AGRICULTURE IN THE ARCTIC ZONE
Authors: Barashkov Al'bert Efimovich
Published: October 2023

This scientific article is devoted to the study of the characteristics of agriculture in the Arctic zone. The Arctic region is characterized by extreme climatic conditions, which pose special challenges for agriculture. The article examines the factors influencing the development of agriculture in the Arctic, and also proposes solutions and innovative approaches for the sustainable development of the agricultural sector in this region.
Forage oat (Avena sativa L.) an important transitory crop for feeding animals in Peruvian highlands
Authors: Arias Carbajal Javier , Passoni Telles Fernando Jesús , Vilcara Cárdenas Edgardo Arturo
Published: October 2023

El objetivo principal de esta investigación fue analizar diferentes bases de datos institucionales relacionadas con el área cosechada, rendimiento y producción de los cultivos de avena forrajera, del 2017 al 2022, a nivel regional y nacional. Para ello, se tomó información de datos estadísticos de 14 regiones donde se cultiva avena en el Perú. La presente investigación tuvo un enfoque cuantitativo no experimental, al utilizar los datos proporcionados por el Instituto Nacional de Estadística e Informática (INEI) y el Ministerio de Desarrollo Agrario y Riego (MIDAGRI). Los datos recolectados fueron organizados en un grupo de hojas de cálculo de Excel 365, posteriormente se utilizó el mismo software para el procesamiento y análisis de los datos. Los resultados mostraron que la avena tuvo la mayor superficie sembrada entre los cultivos transitorios del país. Durante el periodo de datos analizados, la región Puno incrementó su área cosechada de avena forrajera en 16,31 % (68 040 ha en 2017 a 79 139 ha en 2022) y obtuvo el mayor rendimiento medio (28,32 t.ha-1) y producción (2 138 637,62 t) que las demás regiones y produjo principalmente el 80,12 % de la producción del país (2 669 276,67 t) de forraje fresco.
Recent Advances in Biocatalytic Acylation of Alcohols as a Sustainable Target for
Flavor and Fragrance Compounds
Authors: Merabet-Khelassi Mounia
Published: October 2023

Currently, the use of enzymes as efficient tools for the preparation of highly valuable
molecules in various industries has proven to be a tremendous development. The preparation of
esters via biotechnological processes constitutes an important eco-friendly approach for several
industries, especially in the field of flavour and fragrances. This is particularly due to the accrued
customer’s interest in products labelled as natural ensured by using enzymes as natural catalysts.
This mini-review article is dedicated to underline the recent advances (from 2010 to 2022) in the
bio-acylation of achiral and chiral alcohols (esterification and transesterification). The preparation
conditions, such as enzyme nature, acyl donor, solvents, etc., are highlighted.
Inhibitory Effects of Carvacrol on Biofilm Formation in Colistin Heteroresistant
Acinetobacter baumannii Clinical Isolates
Authors: Pakzad Iraj , Yarkarami Fatemeh , Kalani Behrooz Sadeghi , Shafieian Mahnaz , Hematian Ali
Published: October 2023

Background:

The ability of bacteria to form biofilm is an essential strategy for creating
stable infections. This issue is more critical in Acinetobacter bauamannii as a hospital pathogen.
Today, the control of biofilm formation and solutions to prevent or remove biofilm is being developed. Carvacrol has been considered an anti-biofilm compound in significant bacteria. This study
investigated the anti-biofilm effect of Carvacrol on biofilm formation in clinical colistin heteroresistant isolates of A. baumannii.

Methods:

About 22 clinical strains of A. baumannii were collected from Motahari Hospital in Tehran, Iran, in 2019. Biochemical and genotypic methods confirmed these isolates. Colistin heteroresistance was determined by the Standard PAP method. Carvacrol's antibacterial and anti-biofilm
activity was determined according to the standard protocol.

Results:

About 12 isolates were considered strong biofilm producers and were used for analysis.
Six isolates had hetero-resistance to colistin. Carvacrol at a 512 g/ml concentration showed the best
antibacterial activity against all isolates. The sub-MIC of Carvacrol (256 g/ml) reduced the biofilm
formation capacity, which was statistically significant (p<0.05).

Conclusion:

The results of this study showed that sub-MIC of Carvacrol has anti-biofilm effects in
clinical A.baumannii colistin hetero-resistance isolates.
N-Acetyl Cysteine as an Add-on Therapy is Useful in Treating Acute
Lumbar Radiculopathy Caused by Disc Herniation: Results of a
Randomized, Controlled Clinical Trial
Authors: Heidari Bijan , Seyedian Zeinab-Alsadat , Mehrpooya Maryam , Ahmadimoghaddam Davoud , Mirjalili Mahtabalsadat , Ghiasian Masood
Published: October 2023

Background:

Available experimental and clinical evidence indicates that N-Acetyl
cysteine (NAC) may have an analgesic role in specific pain conditions, particularly neuropathic
pain. Thus, we hypothesized that NAC supplementation might be also helpful in decreasing pain
and improving pain-related disability in patients with acute radiculopathy. We designed this
study to investigate the potential use of NAC-adjunctive treatment to Nonsteroidal Anti-
Inflammatory Drugs (NSAIDs) in patients with acute radiculopathy secondary to lumbar
intervertebral disc herniation.

Methods:

Sixty-two patients diagnosed with acute lumbar radiculopathy associated with disc
herniation were randomly allocated to the NAC or the placebo groups. Besides naproxen at a
dose of 500 mg twice a day, participants based on their allocation group started with NAC or
matched placebo at a dose of 600 mg twice a day for eight weeks. The pain severity, measured
by the Visual Analog Scale (VAS), and pain-related disability measured by the Oswestry
Disability Index (ODI) were measured at baseline and weeks 2, 4, and 8 of treatment. Global
improvement of symptoms rated by Patient and Clinical Global Impressions of Change (PGIC
and CGIC) was also recorded at the end of week 8. All analyses were conducted on an Intentionto-
Treat (ITT) analysis data set.

Results:

A comparison of the VAS and ODI scores at weeks 2 and 4 of the treatment between
the two groups did not show a significant difference. In contrast, from week 4 to week 8, we
noticed a significantly greater reduction in the mean VAS and ODI scores in the NAC group
compared to the placebo group (p-value <0.001 for both variables). In parallel with these results,
also, more NAC-treated than placebo-treated patients achieved treatment success defined as
"very much" or "much improved" on CGIC and PGIC scales, and these differences reached a
significant level (p-value = .011 and p-value = .043).

Conclusion:

This study suggested that NAC might be a relevant candidate for adjunct therapy
in managing acute lumbar radiculopathy. Additional clinical trials are needed to validate these
findings.

Trial Registration:

The trial was registered at Clinicaltrials.gov (identifier code: IRCT2012021
5009014N381). Registration date: 2021-02-06.
Investigating the Relationship between the Attitude Towards Infertility
and Stress Coping Strategies among Couples undergoing Assisted
Reproduction Treatment
Authors: Anjom Rouz Fatemeh , Rahnavardi Mona , Hafezi Vahideh , Rafat Fatemeh , Leili Ehsan Kazemnezhad , Shayan Arezoo , Karami Zahra
Published: October 2023

Introduction:

Infertility and its treatment methods among couples have psychological
and social consequences. To encounter these consequences, coping strategies are commonly
used, which are influenced by various factors, such as the attitude of couples toward infertility.

Objective:

This study aims to determine the relationship between attitudes toward infertility and
stress-coping strategies among couples undergoing Assisted Reproduction Treatment, referring
to the infertility clinic of Al-Zahra Educational Center.

Methods:

This study was a cross-sectional study performed on 153 couples referred to Al-Zahra
Infertility Clinic in Rasht. Three instruments (demographic questionnaire, attitude, and Lazarus
coping strategies questionnaire) were used with regard to the inclusion restrictions

Results:

Between the two variables of individual and social information factors and the attitude
of couples toward infertility, only the duration of infertility factor revealed a significant
relationship (p <0.05); and in explaining the relationship between individual and social variables
and coping strategies, the lack of insurance in both genders with an emotion-oriented strategy,
the female infertility factor in women with the confrontational adjustment domain, and treatment
in a discontinuous way in both genders have a significant relationship with the problem-oriented
domain (p <0.05). Accountability and problem-solving strategies in women and an escapeavoidance strategy in infertile men have been identified as the most important predictors of
attitude toward infertility.

Conclusion:

There is a relationship between attitudes toward infertility and coping strategies.
However, the impact of community culture on the type of coping strategies used in this study has
led to different results in some cases from other studies
Three Ways of Doing Philosophy of the City
Authors: Mueller-Salo Johannes
Published: October 2023

In this paper, I propose to subdivide philosophy of the city into three more specific areas of study. First, philosophy of the city as urban epistemology and philosophy of the urban sciences focusses on problems of experiencing and knowing cities and of generating scientific knowledge about cities (sect. 2). Second, philosophy of the city as urban normative theory seeks to interpret and spell out the central categories of practical philosophy—the right, the good, the aesthetic, the democratic etc.—for urban contexts (sect. 3). Third, applied philosophy of the city aims to combine philosophical analysis with the search for practical solutions and concrete possibilities for change (sect. 4). The benefit of such a subdivision of the field is twofold. On the one hand, this systematization clarifies the mutual relations between philosophy of the city, other branches of philosophy, and other urban sciences. On the other hand, it helps identifying open question and blind spots within the current debate and, thereby, opens up new directions for future research in philosophy of the city.
“To connect, you have to listen”
Authors: Kociubuk Jacqueline , Campana Kathleen , Martin Michelle , Mills J. Elizabeth
Published: October 2023

Library and information science (LIS) scholarship has increasingly become aware of disconnects between the traditional curriculum and real-world soft skills employers value in future public library professionals, particularly in regards to being able to engage with underserved communities. To address this gap, MLIS students at two iSchools participated in a field-based social justice assignment that required them to identify an underserved community group they wanted to learn more about, and then collaborate with and interview a member of the group or a community organization that was working with the group. Students completed a written reflection about the experience that the researchers analyzed to understand how a field-based social justice assignment can foster soft skill development for LIS students. Findings indicate that the field-based assignment supported students’ development of three soft skills important for both LIS careers and social justice work: cultural competency, communication, and reflexivity.
More than ESL
Authors: Siebold Connie , Yimin Xiao
Published: October 2023

International students are frequently consolidated into a monolith of students with language needs and information poverty, constituting a disservice to both students and the library staff who seek to better serve them. In this study we interview international students to better understand the potential for cultural collaboration in programming in an academic library setting, and the barriers that keep students from participating. Our findings broaden the view of international students from remedial library users in need of catch-up information literacy and language education, and position them more holistically as potential full partners in programming efforts moving forward.
Teaching social work concepts to LIS students
Authors: Johnson Sarah C.
Published: October 2023

While there has been tremendous growth in the number of partnerships between social work and public libraries in the last fifteen years, an educational gap exists in teaching students about social work concepts within library and information science (LIS) graduate curricula. Recent scholarship does speak to the importance of integrating social work skills and knowledge into LIS coursework, yet little has been written about what this instruction looks like in practice. This thought piece demonstrates an originality of ideas by describing the content, structure, and goals of a cross-disciplinary graduate course entitled Library Social Work. In doing so, the author aims to illustrate the significance of incorporating concepts and themes into LIS curricula to better prepare students for the field of public librarianship and ultimately to benefit library patrons and librarians themselves.
Developing Children’s Data Literacy through Navigating, Video-logging, and Making in a Library
Authors: Jung Yong Ju
Published: October 2023

Data literacy means the ability to understand, evaluate, collect, make, and use data for ethically appropriate purposes (Prado & Marzal, 2013; Yoon & Copeland, 2020). Despite its importance in the 21st century, data is often regarded as a difficult area that only some professional adults can deal with, and most children do not have enough opportunities to feel that their everyday life is indeed connected to data and find it interesting (Acker & Bowler, 2018). To situate data in children’s own lives and the spaces they usually go to (Stornaiuolo, 2020), a design-based research project was conducted by designing and implementing an educational program for children and their families about data literacy in non-computational ways in a public library. Two main sessions (1.5-hour long each) and one optional making session included navigating the whole library space while video-logging with a GoPro camera and worksheets; creating their own creative data visualizations with drawing and making tools (e.g., color papers); making artifacts with maker technologies and brainstorming a metadata structure about the artifacts. Video data from GoPro cameras were collected and preliminary analysis was conducted. Findings show how children could make different observations of familiar objects (e.g., books, tables) in the library and turn their observation to the perspective of “data” and how different types of non-computational activities could align with children’s basic understanding of data.
Integrating the New ALA Core Competences of Librarianship into the LIS Curriculum
Authors: Hirsh Sandra , Saunders Laura , Bright Kawanna , Davis Rebecca , Hands Africa , Salaba Athena , Villagran Michele , Williams Rachel
Published: October 2023

The ALA Core Competences of Librarianship (ALACCs) codifies the essential skills, knowledge and abilities expected of professional librarians and allied professionals in a set of nine competencies. The ALACCs were significantly revised and updated over a period of five years, and were approved by ALA Council in January 2023. The goal of this session is to bring together LIS faculty from across the curriculum to discuss how they are either currently incorporating the new competences into their courses or how they envision they could do this.
Empathy, Confidence, and De-Escalation
Authors: Williams Rachel , Dumas Catherine , Ogden Lydia , Porwol Luke , Flanagan Joanna , Tillinghast Julia
Published: October 2023

This research analyzes the results of a study that is part of a larger, interdisciplinary, and multi-institutional project that examines the usability and effectiveness of VR training for library and information science (LIS) graduate students and professionals in gaining skills for interacting effectively with patrons in crisis. This paper reports on the findings related to the effectiveness of VR training for teaching empathy, confidence, and de-escalation skills for LIS graduate students. The findings illustrate that VR has the potential to impact LIS graduate education by reaching a wider audience that introduces training in low-stakes, immersive environments and that does not pose harm to patrons in crisis. This study also contributes innovative approaches that support training in skills including empathy, confidence, and de-escalation.
Professional Competencies of Canadian LIS Graduates
Authors: Hill Heather , Mills Melanie
Published: October 2023

This study aims to determine current competencies necessary for graduates of Canadian library and information science (LIS) programs. Perspectives from different communities of interest, including current students and graduates from LIS programs, staff and employers of LIS graduates, and library school faculty (full-time and contingent) from across Canada were gathered via a nationally disseminated survey in 2023.  Competency areas include general skills as well as communication, user services, management, and technology. Early findings suggest the importance of established areas of practice, such as selecting and evaluating resources, while emergent areas of priority were also identified, including the importance of equity, diversity, and inclusion, and understanding the responsibilities of libraries in decolonization, Indigenization, and reconciliation efforts.