bluuebunny/crossref_metadata_2025 huggingface dataset:
Utilitarianism: Greatst Impediment to Justice
Authors: Haokip S. Nengneithem
Published: September 2022

This paper evaluates the validity of the foundational ethical conception of Justice and its contesting contradictory conception, Utilitarianism in framing the institutional structure of a nation. Thereby the paper asserts the importance of Justice and certain virtues to a nation’s rise and fall and observes greatest impediment of Justice in the idea of Utilitarianism. While Utilitarianism advances its own conception of Justice, based on critical-theoretical approach the article advances three-fold arguments in order to reprove Utilitarianism of its claim. Utilitarianism is not a viable form of Justice since the theory represents a form of egoism, is structurally inconsistent to sound ethical doctrine, and because it has dissolved the end and means dichotomy.
TABLETLERDE GLİKLAZİT MİKTAR TAYİNİ İÇİN SPEKTROFOTOMETRİK YÖNTEM GELİŞTİRME VE DOĞRULAMA
Authors: LELEKA Lidiia , VASYUK Svitlana
Published: September 2022

Objective: A new spectrophotometric method for the gliclazide quantitation in dosage forms has been developedMaterial and Method: The subjects of the study were modified-release tablets ("Diaglizide" 80 mg, "Diaglizide MR" 60 mg, "Diaglizide MR" 30 mg, "Diabeton" MR 60 mg, "Gliklada" 60 mg). As a reagent, bromocresol green in acetone was used. Analytical equipment: spectrophotometer Specord 200, electronic scales АВТ-120-5DM.Result and Discussion: It has been experimentally determined that gliclazide reacts with bromocresol green in acetone medium at room temperature to form a yellow product with maximum absorption at 411 nm. The method was validated for linearity, accuracy, precision, and robustness. The agent’s optimal concentration was established and the stability of the investigated solutions was checked by measuring their optical density for 30 minutes. Subordination of Beer's law is observed in the range of 62.00 - 94.00 mg/100 ml. The limit of detection is 4.02∙10-6 g/ml, which indicates a high sensitivity of the reaction. The proposed method is validated according to the requirements of the State Pharmacopoeia of Ukraine. The results of the study show that the developed method is simple and affordable to implement and can be used to determine gliclazide in drugs in laboratories for quality control of dosage forms.
PERILAKU COPING OLEH STREET LEVEL BUREAUCRAT PENANGANAN BENCANA COVID 19 DI KOTA BENGKULU (STUDI PADA BADAN PENANGGULANGAN BENCANA DAERAH)
Authors: Rahayu Desita , Romdana Romdana , Marseven Redho Rezki
Published: September 2022

Street Level Bereucrats who usually handle disaster management received additional mandates as the task force for handling Covid 19 in accordance with policy of Bengkulu Mayor No. 167/2020. Having no experience in disasters pandemic and limited skills can cause problem in emergency services. This condition has caused street-level bureaucrats to do "coping behavioral". The locus of this research is Street Level Bereucrats of BPBD Bengkulu. This is a case study research in which Street Level Bereucrats as the population, and snowball sampling. The data used are primary and secondary data with interview techniques, observation and documentation study. The results showed that coping mechanism was done by Street Level Bereucrats in two ways: routines and simplification. The Routines mechanism are rationalizing services, client registration, and resources by placing personnel according to their skills and educational background, controlling risks, namely by improving disaster public service skills. The simplification mechanism is also carried out by simplifying work procedures, especially in emergency situations and preparing action plans that may have to be carried out.
IMPLEMENTASI ELECTRONIC GOVERNMENT MELALUI PROGRAM PENERIMAAN PESERTA DIDIK BARU (PPDB) ONLINE SEBAGAI UPAYA PENINGKATAN PELAYANAN PENDIDIKAN KOTA BEKASI
Authors: Muis Abdul , Riyadi Rizky , Novita Dila
Published: September 2022

The development of information technology has entered various fields, one of which is the use of information technology and telecommunications in public services in the field of education. Based on the Ministry of Education and Culture No. 51 of 2018 concerning the improvement of online New Student Admission which makes it easier to register, and minimizes queues, effective time without queuing which can improve the quality of New Student registration. This study aims to analyze the Implementation of New Student Admission and the factors that influence New Student Admission. The research paradigm uses constructivism paradigm, case study research design, qualitative research methods with data acquisition techniques by observation and interviews. The results of the study concluded that the implementation of Online New Student Admission greatly facilitates the registration of prospective students in terms of time, data that is accurate, effective and efficient. Even so, there are several shortcomings in the Implementation of New Student Admissions, namely an inadequate internet network, the high cost of the internet network, the number of parents who do not understand Information Technology Science, the lack of maximum socialization regarding New Student Admission such as coordinate points or zoning systems.
ESTIMASI BESARAN EMISI KARBON DI KABUPATEN BANYUMAS (Studi Kasus Tahun 2005-2016)
Authors: - Adrian , Nugratama Sony
Published: September 2022

Kegiatan manusia merupakan penyebab utama pemanasan global (dalam Intergovernmental Panel on Climate Change (IPCC), 2007). Hasil diskusi mengintisarikan  bahwa kenaikan suhu bumi tidak boleh melampaui 20C pada tahun 2025, untuk membatasi akibat buruknya bagi hidup manusia. Iklim yang semakin panas akan mempengaruhi  ketersediaan  air serta meningkatkan  intensitas  kondisi cuaca ekstrim seperti badai dan kekeringan. Banyak petani di Indonesia sudah merasakan hal ini dalam kesulitan mereka untuk memperkirakan waktu tanam dengan musim yang semakin tidak menentu (DNPI dalam buku NRDC, 2013). Estimasi besaran biomasa yang dihitung (Y), adalah besaran nilai simpanan karbon yang hilang, karena adanya perubahan tutupan vegetasi terestrial dalam bentuk (a) luasan (ha), dan (b) besaran biomas (ton/ha). Perubahan tutupan vegetasi ditelusuri dari Citra Lansat Band 54TM yang bersumber dari Lapan tahun  2005 dan  tahun  2016.  Perubahan  tutupan  lahan  dalam  hal  ini  diasumsikan  sebagai  perubahan terhadap tutupan vegetasi. Perubahan (delta) luasan dan tutupan vegetasinya, sebagai dasar perhitungan selanjutnya. Perubahan terbesar adalah berkurangnya areal sawah sebesar 4008,805 ha atau 15,62% dari luas sawah sebelumnya. Hasil dari konversi lahan ini mengakibatkan luasan areal ruang terbangun antara tahun 2005-2016 meningkat total seluas 3089,694 ha menjadi 20.006,481 ha. Selama  tahun  2005  sampai  2016  terdapat  kecenderungan  yang  terus  menurun  terhadap cadangan karbon sebesar 3.364,83 ton carbon atau 2.348,94 ton C02eq. Hal ini berarti secara keseluruhan perubahan tutupan lahan di Kabupaten Banyumas menyumbangkan emisi karbon setiap tahunnya sebesar 0,08085 ton/ha/tahun.
THE EFFECT OF THE EXISTENCE OF THE SHOPPING MARKET ON THE SOCIAL ECONOMIC LIFE OF THE COMMUNITY
Authors: Cahniar Rina , Hermanto Hermanto
Published: September 2022

The purpose of the study was to determine the socio-economic life of the community and the influence of the existence of supermarkets on the socio-economic life of the community in Wanasari Village, Cibitung District, Bekasi Regency. The research method used is descriptive method (descriptive research). Data collection techniques are observation, interviews, questionnaires, documentation studies, and literature studies. The research sample was 60 people with proportional random sampling technique. Based on the results of the study, it can be concluded that the existence of supermarkets has an impact on the socio-economic life of the people in Wanasari Village, especially people who work directly as supermarket employees and people who carry out activities around supermarkets. The socio-economic life of the community includes education, social interaction, employment, job opportunities, and income. From the several aspects measured, almost all of them experienced an increase from before the supermarket was after the supermarket.
EFFORTS TO INCREASE STUDENTS' INTEREST IN LEARNING GEOGRAPHY OF POPULATION DYNAMICS MATERIALS WITH THE APPLICATION OF THE DISCOVERY LEARNING MODEL IN CLASS XI IPS AT SMA NEGERI 1 DENPASAR
Authors: Rodiaman Idan
Published: September 2022

Education in the life of a country plays a very important role to ensure the survival of the state and nation, because education is a vehicle to improve and develop the quality of human resources. This is a big demand for the world of education in Indonesia. Improvements in various components of education continue to be made, starting from facilities and infrastructure, teaching and educational staff, to the learning process. It is undeniable that improving the quality of education is a must in order to produce human resources who are responsive to various changes in all aspects of life. This research uses an experimental study method by applying learning to the Population Dynamics material with scientific learning, the Discovery Learning model. The instrument used is an instrument used to replace the learning process in the form of an observation sheet and also uses an instrument to see student learning outcomes by using a brief description. The results showed that the scientific approach in learning was able to increase students' confidence in dealing with tests (assessment) and make students better able to master learning in high order thinking skills (HOTS).
RANCANG BANGUN DAN ANALISA PERFORMA ALAT PENUKAR PANAS DOUBLE PIPE MENGGUNAKAN METODE LMTD: SEKALA LABORATORIUM
Authors: Hendratama Handik
Published: September 2022

A heat exchanger is a tool that is used to increase or reduce fluid temperatures. One type of this tool is a type of double pipe, this type is the simplest if compared to other types of heat exchanging devices, where hot fluid flows in the inner tube and cold fluid flows in the anulus. This study aims to analyze the efficiency of laboratory scale heat exchanging devices with water  hot and cold fluids. The result shows the average effectiveness of this equipment is 20% this result is better when compared to several other studies which on the laboratory scale only show maximum efficiency at 17%. The fouling factor is an obstacle that causes a decrease in the effect of heat exchangers, the greater the fouling factor, the greater the heat resistance caused by the pipe. This study shows the amount of Fooling factor of 0.006, the value is greater than the available Fouling Factor constant. The results stated that there is a relationship between remediable numbers (Reynold numbers) with the amount of heat transferred by heat fluid. The greater the value of Reynold the greater the expressed heat. Even though it has high efficiency, this equipment can still not be used because of some considerations such as low efficiency and efficient..
RANCANG BANGUN FORKLIFT SISTEM SLING
Authors: - Paridawati , Apriliansyah Mario , Iswanto Hari , Rohimin Amar , M Ade Fuad
Published: September 2022

Forklift adalah salah satu alat pengangkat yang berfungsi untuk memindahkan barang dari suatu tempat ke tempat lainnya, foklift yang merupakan salah satu peralatan mekanik dan peralatan utama bongkar muat yang selalu di gunakan dalam kegiatan bongkar maut. Tujuan penelitian adalah untuk melakukan rancang bangun mesin forklif sistem sling. Penelitian diawali dengan rancang desain alat, lalu melakukan pembuatan rancang bangun alat. Setelah itu dilakukan uji kinerja alat untuk mengetahui kinerja forklif sistem sling.  Hasil analisa pehitungan pada forklift adalah, beban maksimum yang dapat diangkat oleh alat adalah 50 kg. dan Kemampuan Forklift per hari adalah  200 kg / hari.
PENGARUH VARIASI PARAMETER PEMBEBANAN TERHADAP GETARAN PADA MESIN KOMPRESOR TORAK
Authors: Sadiana Riri , Surahto Aep , Ekawati Fatimah Dian , Billah Mu’tasim
Published: September 2022

Getaran terjadi karena adanya gaya eksitasi, hampir semua mesin yang bergerak akan bergetar meskipun mungkin intensitasnya sangat kecil. Eksitasi dapat terjadi karena adanya ketidakseimbangan pada mesin itu sendiri. Getaran juga dapat menimbulkan ketidak presisian atau menurunkan kwalitas kerja mesin kompresor itu sendiri dan getaran juga dapat merusak kontruksi mesin kompresor. Penelitian dilakukan untuk menguji besarnya getaran yang terjadi pada kompresor torak dengan menggunakan alat ukur getaran Vibrometer dan mencari penyebab getaran pada kompresor torak dengan mengetahui struktur mikro bearing dan menguji kekerasan material bearing. Hasil analisis semua parameter pembebanan terhadap getaran pada kompresor masih dalam keadaan baik dan dalam batas toleransi. Getaran yang diukur menggunakan alat vibration meter menunjukkan bahwa pengukuran percepatan getaran yang tertinggi adalah pada putaran320 rpm dan terendah pada putaran 405 rpm.
ISLAMIC SPIRITUAL RELIGIOUS MOVEMENT IN MAJELIS DZIKIR AS-SAMAWAAT AL-MALIKI AS A NATIONAL DEFENSE AND SECURITY STRATEGY
Authors: Rusmanto Yudi , Nasir Syamsun , Utama Anang Puji
Published: September 2022

The role of the As-Samawaat Al-Maliki Dhikr Council in Kohod Village the Dhikr assembly led by the charismatic cleric Hadratus Shaykh K.H Sa'adih Al-Batawi has a platform for Islamic spiritual development capable of contributing to building the ummah and national society in general with its nationalism programs that can be observed from their various actions and existence both internally and externally. The study and implementation of programs that always prioritize the integrity of the Unitary State of the Republic of Indonesia are widely supported by generals and units of the armed forces/TNI and Polri who continue to be close to their various activities, especially recitations and visits of military figures, both active and retired, to ask the leadership of Assamawat Al -Maliki, namely K.H. Saadih Al-Batawi to provide contributions and advice in nation-building and national security defense. This study uses a descriptive qualitative method. The synthesis of the role of the As-Samawaat Dhikr Council is very organ and fundamental in the eyes of Muslims, especially in the two aspects of its building strength, namely the development of the soul (spiritual) and the body. In building the body/physically As-Samawaat has prepared a legacy for future generations by making a worship center (As-Samawaat Mosque), the best spiritual facilities/Sufism education laboratory, and preparations for building school/Islamic boarding schools in an environment that is arranged with the AMDAL landscape. In making the soul (spiritual) As-Samawaat Al Maliki prepares various mental and national character development programs for the congregation and students to become a beacon as ambassadors of peace in the development of the nation and state of the Republic of Indonesia to always maintain and build very expensive independence.
Effect of Blended Learning on Periodontal Instrumentation Class for Dental Hygiene Clinic Theory and Practicee
Authors:   The Korean Society of Oral Health Science, Choi Yong-Keum , Son Jung-Hui , Choi Eun-Mi , Park Hyang-Ah
Published: September 2022

Objectives: This study aimed to apply blended learning and evaluate its effectiveness in the periodontal instrument class for dental hygiene clinic theory and practice.
Methods: Thirteen students were subjected to the traditional mode of instruction and 12 students were subjected to blended learning. The students’ instrument ability was evaluated before and after class. Non-parametric tests were employed in all analyses.
Results: After completing the class, the students’ overall comprehension increased (p<0.05). Moreover, those who participated in blended learning had a higher periodontal instrument operation ability (p<0.05).
Conclusions: Blended learning may be applied in periodontal instrument class for dental hygiene clinic theory and practice, and it may be established as an effective educational method for on-offline classes.
Effects of Obstructive Sleep Apnea Risk Factors on Mental Health (PHQ-9) and Quality of Life (EQ-5D) in Middle-aged Koreans: Using Data from the National Health and Nutrition Examination Survey 2020
Authors:   The Korean Society of Oral Health Science, Kang Hyun-Kyung , Seong Mi-Gyung , Kim Yu-Rin
Published: September 2022

Objectives: The purpose of this study is to provide basic data to determine the effects of obstructive sleep apnea on mental health and quality of life.
Methods: This study used data from the National Health and Nutrition Examination Survey 2020, and a complex sample linear regression analysis was performed to confirm the effect of obstructive sleep apnea on mental health and quality of life.
Results: If there were risk factors for obstructive sleep apnea, there were adverse effects on mental health and quality of life (p < 0.05).
Conclusions: Based on the above results, it is necessary to continuously promote the importance of the treatment of obstructive sleep apnea in the field of oral medicine.
Degree of Self-competency Diagnosis of Some University Professorsjor
Authors:   The Korean Society of Oral Health Science, Lee Sun-Mi , Choi Won-Joo , Kim Young-Im
Published: September 2022

Objectives: This study attempted to allow instructors to reflect on their teaching activities and seek efficiency measures for continuous evaluation and utilization through a diagnosis of teaching competency.
Methods: The study period was from 261 professors at some universities were analyzed. Using SPSSWIN 23.0.
Results: Basic competency was 4.45 points and lecture competency was 4.36 points, slightly higher, basic competency was 4.60 points for professionalism and beliefs as a professor, and motivation was the highest for lecture competency with 4.52 points. However, in terms of lecture competency, those in their 60s or older (4.49 points) were statistically significantly higher than those in their 30s (4.21 points) (p<.05). The correlation of teaching competency for each area showed statistically significant positive correlation in all areas.
Conclusions: University professors will need to clearly recognize what their insufficient teaching competencies are, and continuous efforts will be needed to strengthen them, and teaching support organizations will need various program support to develop and supplement their insufficient competencies.
The Effect of Dental Hygiene Students' Academic Situation on Evaluation Concerns Perfectionism and Self-Handicapping: The Mediating Effect of Fear of Negative and Positive Evaluation
Authors:   The Korean Society of Oral Health Science, Kim Yu-Rin , Jang Kyeung-Ae
Published: September 2022

Objectives: The purpose of this study was to examine the mediating effects of the fear of negative evaluation and the fear of positive evaluation on perfectionism and self-handicapping and to determine the difference between them.
Methods: This study was conducted with 135 students enrolled in the department of dental hygiene. Hierarchical regression analysis was performed to confirm the mediating effects of negative and positive evaluations in relation to perfectionism and self-handicapping.
Results: The study showed that perfectionism was a factor affecting self-handicapping, and that fears of a positive evaluation had a greater mediating effect than fears of a negative evaluation.
Conclusions: It is important to establish your own values and to cultivate positive thinking. An atmosphere of counseling and of learning should be established so that the criteria for success can be objective rather than arrived at by comparing yourself with others.
Effect of Health Department Students' Major Satisfaction and Communication Ability on Personality
Authors:   The Korean Society of Oral Health Science, You Eun-Ji , Shin Min-Woo , Min Hee-Hong
Published: September 2022

Objectives: This study intends to identify the relationship between health students' personality, major satisfaction, and communication ability level and use them as basic data for character development of health students.
Methods: This study was prepared using the self-report questionnaire method for convenience extraction of college students from health-related universities located in Daejeon and Chungcheong Province from March 29 to April 15, 2021. Data analysis was performed using IBM SPSS Statistics 22.0 program.
Results: Based on 5 points, personality was 4.05, major satisfaction was 3.70, and communication ability was 3.55. Factors affecting the personality level of health students were college life satisfaction, communication ability, and major satisfaction, and the most influential factor was college life satisfaction, which accounted for 40.3%.
Conclusions: As a result of the above, efforts are required to increase college life satisfaction, communication ability, and major satisfaction as a measure to strengthen the personality level of health students.
The Effect of Dental Hygienists' Professional Self-Concept on the Practice of Dental Hygiene in the Elderly: Focusing on the Mediating Effect of Empathy
Authors:   The Korean Society of Oral Health Science, Jang Kyeung-Ae , Yoon Hyun-Seo
Published: September 2022

Objectives: This study was conducted to understand the effect of dental hygienists' professional self-concept on the practice of dental hygiene, focusing on the mediating effect of empathy in the elderly.
Methods: This study was conducted with from the dental hygienists' in some areas of Busan and Gyeongnam.
Results: In the relationship between the dental hygienists' professional self-concept and the practice of dental hygiene for the elderly, the results of the empathy mediating effect of the elderly showed that it was completely mediated and meaningful.
Conclusions: Dental hygienists recognize the importance and necessity of empathy for the elderly. It is suggested to develop and participate in educational programs that can increase empathy.
Factors that Affect Anxiety Related to Radiation Exposure Among Patients in a Dental Medical Institution
Authors:   The Korean Society of Oral Health Science, Lee Eun-gyeong , Jang Gye-won
Published: September 2022

Objectives: This study was conducted to investigate how anxiety in dental patients regarding radiation exposure can be reduced.
Methods: The study was conducted in dental facilities during the six months from August 2019 to January 2020 to investigate the anxiety of patients concerning radiation exposure. It then analyzed the factors affecting their levels of anxiety regarding exposure.
Results: The results showed statistically significant differences between anxiety relating to dental radiation exposure and knowledge of radiation (-0.252, p < 0.01) and perceptions of radiation (-0.582, p < 0.01). An examination of the factors affecting the anxiety of dental patients regarding exposure to radiation showed that a high recognition of the need for dental radiography (p < 0.05) and more negative perceptions of radiation (p < 0.001) resulted in greater anxiety regarding radiation exposure (p < 0.001).
Conclusions: In order to reduce anxiety about radiation exposure, educational materials should be produced and patient education conducted so patients can have correct knowledge and perceptions of dental radiation. In addition, relevant regulations or legal guidelines should be prepared so that radiation safety education for patients can be practiced systematically.
Deconstructing Afghan Historiography: A Case Study of Hazara History Writing
Authors: Khan Rabia Latif
Published: September 2022

This article examines Hazara history writing, exploring how Hazara authors highlight the community’s formerly low socio-economic status and stigma attached to “being” Hazara. It also shows how in the 1980s and 1990s a shift in ethnic consciousness among Hazaras led to a new sense of pride and confidence, which continues to the present. The analysis focuses on two websites, Hazara.net and Hazara International, which are key social spaces for engagement with Hazara historiography. These websites are central to the ongoing production of an indigenous community history. These online spaces allow for the documentation, preservation, and propagation of Hazara history from a community-oriented lens.
Early Thinking about Likings and Dislikings
Authors: Blackson Thomas A.
Published: September 2022

In Plato’s Protagoras, Socrates argues that ‘the many’ are confused about the experience they describe as ‘being overcome by pleasure’. They think the cause is ‘something other than ignorance’. He argues it follows from what they believe that the cause is ‘ignorance’ and ‘false belief’. I show that his argument depends on a premise he does not introduce but they should deny: that when someone is overcome by pleasure, the desire stems from a belief. To explain why Plato does not make Socrates introduce this premise, the account I construct is speculative. It starts from the assumption that Plato is thinking through an understanding of human beings and what they must do to live good lives that he takes the historical Socrates to set out.
A Review on Social and Economical Status of Asian Weaver Ants (Oecophylla smaragdina)
Authors: Divyangi Patel , Nikunj Bhatt
Published: September 2022

The Asian weaver ants (Oecophylla smaragdina) are one of the most social insects that actually work effectively for their existence from generation to generation. These ants are totally social as they always recruit their activities like nesting, foraging, migrating, and protecting their nest mates in huge number. Weaver ants also plays role as pest managing in several farms by dominating in numbers and eliminating other pests by their presence. In countries like Thailand and other Asian countries they have propogated naturally and artificially in order to combat against other pest impeding the trees to destroy them. Additionally these ants also have different castes to manage all the activities to continue their livelihood that work depending upon their actual needs. These ants also build arboreal nests on trees of mango, ashoka and other citrus plants by bringing the close proximity leaves. The workers squeeze up the unfertilized larva which helps to ooze out the silk like fluid that acts as a packing material to seal the edges of leaves and build a nest. Oecophylla smaragdina shows courtship behavior during nuptial flight during monsoon seasons to expand their colony. The female and male alate exchange their gametes in air and later on locate their own nest from the colony thereby laying eggs once the female ant loses its wings. These ants are of economical importance as their larvae are consumed by people of many countries as highly protein diet in a fried form as fritter. They are also highly possessive for their nest mates. Weaver ants forage socially by making different groups to locate, reach and lodge the food inside the nest by using landmarks.
A New Species of the Genus Microtendipes Kieffer (Diptera, Chironomidae) from Foothills of Eastern Himalaya, India
Authors: Uttaran Majumdar
Published: September 2022

In this study Microtendipes semicylis sp. nov. has been described based on adult male along with key to males of Microtendipes in Oriental region. It is the first record of this genus from north-eastern India
Effect of Imidacloprid on the Microbial Biodiversity of Soils of Selected Zones of Haryana, India
Authors: Poonam Yadav , Monika Bhardwaj , Divya Vashishth , Mansi Yadav , Pooja Kadyan , Sunita Dalal , Kumar Kataria Sudhir
Published: September 2022

Imidacloprid is one of the most frequently used insecticide in Haryana having a pivotal role in pest management and improvement in crop yield production. This study was performed to investigate the consequences of Imidacloprid on bacterial, actinomycetes and fugal population in soils of selected zones of Haryana, India. The experiment was conducted for 28 days and the samples were taken after 1st, 7th, 14th, 21st and 28th day of Imidacloprid application at various concentrations like T1(1mg/kg), T2 (2mg/kg) and T3(10mg/kg) doses. The number of CFU (colony forming unit) of microbes were grown on appropriate media using serial dilution and spread plate method. The results obtained showed a negative effect of Imidacloprid at T1 and T2 doses in first two weeks of incubation but non-significant effect in last two weeks of incubation on soil microbial number. Imidacloprid stimulated number of heterotrophic bacteria and fungi at T3 with time but a negative effect of N2- fixing and phosphate solubilizing bacteria was observed at each dose and time point in each soil sample. Obtained results showed that these soil microbes were affected by concentration and treatment time of Imidacloprid significantly in soils of each selected zone of Haryana. The results provide a clue about the possible ecological effects of Imidacloprid.
In Silico Approach to Search Various Phytochemicals as Potential Therapeutics Against the Spike Protein from Alpha Variant Strain (B.1.1.7) of SARS-CoV-2
Authors: Diptendu Sarkar
Published: September 2022

Scientists have indeed been attempting to examine many active chemicals identified in plants that would have the effect of restricting the multiplication of SARS-CoV-2 since the onset of the COVID-19 widespread. The worldwide healthcare system has been trying to discover an efficient therapeutic solution because there are no therapeutically authorised medications. Testing of botanical pharmaceuticals could be a feasible method that fight COVID-19 during this crucial moment. The research focused upon the spike protein of SARSCoV2's novel alpha strain, which was initially found in the United Kingdom. The objectives of this paper was to use a molecular docking approach to analyse pharmacological chemicals discovered in plants in order to prohibit the major protease (7DDN) of the SARS-CoV2 alpha variant strain (B.1.1.7). The binding affinity computed with PyRx virtual screening tool, which employed AutoDock Vina as a docking processor, were evaluated. All total 33 phytochemicals were analysed in this research. Hesperidin and broussochalcone A, according to findings of this study, had the strongest interaction (-8.7 Kcal/mol) with 7DDN spike protein. Pectolinarin has the second highest binding affinity (-8.3 Kcal/mol). Rhoifolin had the third highest interaction (-8.2 Kcal/mol), followed by Epigallocatechin, Cannabidiol, and Morin, which all had a docking score of -7.9 Kcal/mol. This study, which aimed to predict the suppressive activities of compounds obtained from plants specifically address 7DDN proteins, discovered a number of things, including that the pharmaceutical is having a significant posture and binding affinity than hydroxychloroquine. Furthermore, in silico drug likeness and ADMET analyses of the phytochemicals demonstrated significant therapeutic advantages. As a conclusion, the present investigation would serve as a springboard for much more exploration to assess the phytocompounds' effectiveness.
Screening of Phytoconstituents from Curcuma longa, Piper nigrum and Murraya koenigii Methanolic Extracts, and In Vitro Efficacy of Their Combinations on Nematode Parasite (Ascaridia galli) of Gallus gallus domesticus
Authors: Rehan S. Ahmad , Asma Masuldar
Published: September 2022

Plants are a natural gift from God to humans. They play a crucial role in maintaining the health of humans as well as the environment. Humans have used medicinal plants to cure a variety of diseases since ancient times, including skin disorders, gastrointestinal issues, respiratory issues, bacterial infections, viral diseases, and parasitic diseases, as they contain a variety of active components (phytoconstituents). Nematidiasis is a parasitic ailment in livestock animals and birds caused by nematode parasites that reduces livestock output. The current work examines the phytoconstituents found in methanolic extracts of Curcuma longa (rhizome), Piper nigrum (seed), and Murraya koenigii (leaf), as well as their interactions. Their extracts were tested in vitro against the parasitic worm Ascaridia galli from the host Gallus gallus domesticus. They contain significant phytoconstituents such as alkaloids, tannins, flavonoids, phenols, glycosides, steroids, and others. When their extracts were combined, they have a high level of action against parasites, indicating a synergetic effect. The amount of activity displayed was dosedependents. Researchers may find the findings useful in controlling nematode infection in farm animals and birds by combining these important natural plants as an alternative source of anthelmintics.
Antioxidant and Antiproliferative Activity of Noni Fruit (Morinda citrifolia) Extracts Against Human Breast Cancer Cell Line (MCF-7)
Authors: Gopal Rengaswamy , Vijayakumar Remya , Karkuzhali M.  , Sharmila J.  , Ashok K.
Published: September 2022

Noni juice, obtained from the fruit of the noni tree (Morinda citrifolia L.), is a popular commodity in the market, particularly in the South Pacific. It is widely used by consumers for the prevention of several lifestyle diseases. Although there is increasing interest in the potential therapeutic use of noni plants, there are no comparative studies on the various commercialized noni fruit juices available to decipher their phytochemical composition and properties against carcinomas. The present study, therefore, aimed to investigate the juice’s anecdotal use as complementary alternative medicine to manage cancer. In this study, we evaluated the cytotoxicity and antioxidant activity of M. citrifolia fruit extracts. DPPH (2,2-Diphenyl-1-picrylhydrazyl) tests were used to assess the antioxidant of the extracts. The cytotoxicity of the MCF-7 breast cancer extracts was performed using the MTT procedure. Antioxidant and anticancer studies showed the potential activity of M. citrifolia fruit extracts. Further work involving more extensive in vitro and in vivo studies are needed to elucidate its anticarcinogenic activities.
Route of Exposure and Impact of Pesticides Pollution on Human Health and Aquatic Ecosystem
Authors: Ram Meena Asha
Published: September 2022

Pesticides have been found in aquatic ecosystems such as groundwater, lakes, rivers and oceans through clogged storm drains, improper disposal, unplanned discharges and accidental spills. Pesticide exposure results in a variety of abnormalities in the human body, including mutagenic or genotoxic impacts. Pesticide-exposed organisms exhibit a wide range of developmental abnormalities, including genital deformities. Herbicides have a direct negative impact on the population size of primary producer. Pesticides accumulate in rivers and fresh water because of the high concentration of pesticides in the agricultural environment. Toxicants produced by humans have been identified as a severe threat to freshwater ecosystems. Pesticide use has led to the drastic decline of the populations of certain fish species. Insecticides, herbicides and fungicides have all been associated with a decrease in several animal species. Pesticides accumulate in the bodies of fish and have an impact on human health as a result of biological cycling and bio-magnification. Not only can pesticides affect fish, but they can also affect the food webs that support them. Pesticides enter the human body through a variety of ways, including the food chain, air, soil, water, flora and fauna and the environment. In pesticide applicators, farmers and farm workers in general, abnormalities and illnesses of the skin have been documented
First Report of Morphological and Molecular Identification of Explanatum explanatum from Domestic Water Buffalo, Bubalus bubalis from Meerut Region, India
Authors: Anju Tyagi , Bhumika Chauhan , Monica Misra , Bindu Sharma
Published: September 2022

Present communication deals with the morphological and molecular studies of Explanatum explanatum collected from the infected liver of abattoirs of domestic water buffalo (Bubalus bubalis). Explanatum explanatum is a digenetic gastrointestinal trematode majorly found in the bile duct and gall bladder of buffaloes in India .The parasite produces productivity loss and occasionally turns out as severe clinical disease leading to pocked in the bile duct mucosa, glandular hyperplasia and thickening of the blood vessels .This is the first report which analyzed the morphological and molecular studies on Explanatum explanatum from Meerut region, India. The 5.8S sequences of rDNA usually distinguish species clearly, including combinations for which morphology gives ambiguous results. This study also suggests that morphological characters along with molecular identification are essential for validation and identification of species and this will serve as a resource for comparative genomics and systematic studies of parasitic trematodes.
Biodegradation of Synthetic Pyrethroid Insecticide Deltamethrin by Stenotrophomonas maltophilia Strain DRNB1
Authors: Victoria K.Johnson Josna , Vimala K. John
Published: September 2022

: Deltamethrin is one of the most used pyrethroid insecticide in different regions of the world. It is the fastacting insecticide that disrupts the cellular sodium channels. The deltamethrin residues are highly retained in environments, particularly in soil and water and have inevitable side effects on natural resources and human health. The most efficient, economical, and environmentally beneficial way of removing deltamethrin from contaminated sites is bioremediation. Bacteria are the most used biological agents in biodegradation studies. Thus, in this study deltamethrin-degrading bacteria Stenotrophomonas maltophilia strain DRNB1 was isolated and characterised. The bacterial growth was analysed by UV-spectrophotometer and deltamethrin degradation was studied by GC-MS analysis. S. maltophilia strain DRNB1 used deltamethrin as the sole carbon source for growth. Deltamethrin degradation efficiency of DRNB1 was 89.2% in insecticide supplemented media and 93% in presence of additional glucose in mineral media. These results implies that S. maltophilia strain DRNB1 could be used as a bioremediation technology for deltamethrin contaminated environments.
Effect of Solar Radiation on Freshwater Fish Puntius bimaculatus (Bleeker) (Cypriniformes: Cyprinidae)
Authors: Raj R. Azhagu , Saravanakarthick. P.  , Palavesam A.  , Prakasam A.  , Balachandar M.
Published: September 2022

Environmental and physical stressors such as sunlight, atmospheric temperature, photoperiod, and UV radiation have a significant impact on all living organisms in the aquatic ecosystem, particularly on rocky shores, shallow water bodies, lakes, and ponds. In this study, the freshwater fish Punitus bimaculatus (Bleeker) (Cypriniformes: Cyprinidae) was exposed to solar radiation for 1h to 2h duration during the summer season from March to May (water temperature 40 ºC to 42 ºC). The stress caused by increased water temperature (40 oC to 42 oC) significantly reduced the physiological activities and alter the metabolism of the fish, particularly carbohydrate, protein, and lipid levels in the experimental fish, and also damaged the muscle tissue. The muscle carbohydrate, protein and lipid content of Punitus bimaculatus reduced when exposed at 40 ºC and 42 ºC . This could be due to the stress-induced on the fish to utilize the stored energy in the body. Punitus bimaculatus muscle tissue showed marked degeneration of the epithelium, disappearance of striations, and thickened septal wall. The continual degradation of primary metabolites is vital for tissue maintenance but is also important in allowing animals to adapt to changing environmental conditions, replace denatured or damaged proteins, mobilize amino acids, and allow metabolic regulation.
Response of Aedes aegypti (L.) Larvae to Seed-Derived Essential Oil and SeedDerived Extract of Moringa oleifera (Lam.)
Authors: Arti Prasad , Kanishtha Acharya
Published: September 2022

Billions of people face severe problems throughout the world due to vector-borne diseases. Effective management of vectors can reduce the burden of vector-borne diseases. The present study was conducted to assess the efficiency of Moringa oleifera (Lam.) seed extract and seed essential oil against Aedes aegypti larvae. Log probit, regression, and ANOVA were carried out to find out the statistical significance. Probit analysis of mortality rates of crude extracts of seeds of Moringa oleifera showed LC50 and LC90 values as 56.53 ppm and 186.50 ppm and for essential oil it was 1414.34 ppm and 5423.48 ppm, respectively against 3rd instar larvae within 24 h of exposure. ANOVA indicated a significant relationship between exposure time and concentration of extracts in imposing mortality to the mosquito larvae. Since seed extract and essential oil were from natural origin so they are safe on non- targeted organisms. The outcomes of present study suggested that the extracts of Moringa oleifera was more effective against larvae than essential oil and can be further used as an eco-friendly mosquito larvicidal agent. The isolated compounds from this plant may also act as a potent larvicide and are worth further study.
A Preliminary Study on the Avifauna of Aranya Udhyan, Gandhinagar, Gujarat, India
Authors: Raval Krutarth , Dimri Mansi , Pandy Maharshi , Sasikumar K.
Published: September 2022

The major focus of the current research was to identify and prepare the checklist of the diverse avifauna population present in the Aranya Udhyan in Gandhinagar, Gujarat, India during the time period of April 2021 to April 2022. Aranya Udhyan is a densely forested area governed by the government body, Gujarat Ecological Education and Research Foundation (GEER). The most avifaunal-friendly habitats can be found here, where there are many trees, less human activity, and dense forests. In this study, a total of 197 species of avifauna belonging to 64 families and 20 orders have been recorded from Aranya Udhyan. A total of 186 species were classified as least concern, 8 as nearly threatened, and 2 as vulnerable. This research provides the Aranya Udhyan with checklist data of avifauna diversity
PLAYING THERAPY CAN REDUCE POST TRAUMATIC STRESS DISORDER (PTSD) IN POST-EARTHQUAKE CHILDREN
Authors:   Faculty of Health Sciences, Universitas Sulawesi Barat, Majene, Indonesia, YULIANI EVA , SASTRIANI  ,   Faculty of Health Sciences, Universitas Sulawesi Barat, Majene, Indonesia,, MURSID ACO ,   Faculty of Health Sciences, Universitas Sulawesi Barat, Majene, Indonesia,, MUZDALIA IKA ,   Faculty of Health Sciences, Universitas Sulawesi Barat, Majene, Indonesia,, HASRIATI  ,   Faculty of Health Sciences, Universitas Sulawesi Barat, Majene, Indonesia
Published: September 2022

Earthquakes lead to Post Traumatic Distress Disorder (PTSD), which is psychological stress trauma after a disaster. Management of PTSD in children is playing therapy. This study aimed to determine the effect of Playing Therapy on Post Traumatic Stress Disorder(PTSD) in children aged 7-12. This research was an experimental research with one group pre-test and post-test design. Thirty-five respondents had PTSD symptoms after the earthquake in Malunda, Majene. The research instrument used was a questionnaire. This study found a significant decrease in PTSD, with p-value = 0.001 = 0.05. It can be concluded that playing therapy affected decreasing Post Traumatic Stress Disorder (PTSD) in children aged 7-12 years who were the earthquake victims in Mekkatta Village, Malunda District.
Self-assembled peptide-paclitaxel nanoparticles for enhancing therapeutic efficacy in colorectal cancer
Authors: Hou Lidan , Zhong Ting , Cheng Peng , Long Bohan , Shi Leilei , Meng Xiangjun , Yao Han
Published: September 2022

Chemotherapy is one of the main treatments for colorectal cancer, but systemic toxicity severely limits its clinical use. Packaging hydrophobic chemotherapeutic drugs in targeted nanoparticles greatly improve their efficacy and reduce side effects. We previously identified a novel colorectal cancer specific binding peptide P-LPK (LPKTVSSDMSLN) from phage display peptide library. Here we designed a self-assembled paclitaxel (PTX)-loaded nanoparticle (LPK-PTX NPs). LPK-PTX NPs displayed a superior intracellular internalization and improved tumor cytotoxicity in vitro. Cy5.5-labeled LPK-PTX NPs showed much higher tumor accumulation in colorectal cancer-bearing mice. Furthermore, LPK-PTX NPs exhibit enhanced antitumor activity and decreased systemic toxicity in colorectal cancer patient-derived xenografts (PDX) model. The excellent in vitro and in vivo antitumor efficacy proves the improved targeting drug delivery, suggesting that peptide P-LPK has potential to provide a novel approach for enhanced drug delivery with negligible systemic toxicity.
Comparison of degradation behavior and osseointegration of 3D powder-printed calcium magnesium phosphate cement scaffolds with alkaline or acid post-treatment
Authors: Kowalewicz Katharina , Waselau Anja-Christina , Feichtner Franziska , Schmitt Anna-Maria , Brückner Manuel , Vorndran Elke , Meyer-Lindenberg Andrea
Published: September 2022

Due to the positive effects of magnesium substitution on the mechanical properties and the degradation rate of the clinically well-established calcium phosphate cements (CPCs), calcium magnesium phosphate cements (CMPCs) are increasingly being researched as bone substitutes. A post-treatment alters the materials’ physical properties and chemical composition, reinforcing the structure and modifying the degradation rate. By alkaline post-treatment with diammonium hydrogen phosphate (DAHP, (NH4)2HPO4), the precipitation product struvite is formed, while post-treatment with an acidic phosphate solution [e.g., phosphoric acid (PA, H3PO4)] results in precipitation of newberyite and brushite. However, little research has yet been conducted on newberyite as a bone substitute and PA post-treatment of CMPCs has not been described in the accessible literature so far. Therefore, in the present study, the influence of an alkaline (DAHP) or acid (PA) post-treatment on the biocompatibility, degradation behavior, and osseointegration of cylindrical scaffolds (h = 5.1 mm, Ø = 4.2 mm) produced from the ceramic cement powder Ca0.75Mg2.25(PO4)2 by the advantageous manufacturing technique of three-dimensional (3D) powder printing was investigated in vivo. Scaffolds of the material groups Mg225d (DAHP post-treatment) and Mg225p (PA post-treatment) were implanted into the cancellous part of the lateral femoral condyles in rabbits. They were evaluated up to 24 weeks by regular clinical, X-ray, micro-computed tomographic (µCT), and histological examinations as well as scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) analysis and compared with tricalcium phosphate (TCP). All materials showed excellent biocompatibility and rapid osseointegration. While TCP degraded only slightly, the CMPCs showed almost complete degradation. Mg225d demonstrated significantly faster loss of form and demarcability from surrounding bone, scaffold volume reduction, and significantly greater degradation on the side towards the bone marrow than to the cortex than Mg225p. Simultaneously, numerous bone trabeculae have grown into the implantation site. While these were mostly located on the side towards the cortex in Mg225d, they were more evenly distributed in Mg225p and showed almost the same structural characteristics as physiological bone after 24 weeks in Mg225p. Based on these results, the acid post-treated 3D powder-printed Mg225p is a promising degradable bone substitute that should be further investigated.