bluuebunny/crossref_metadata_2025 huggingface dataset:
Azərbaycan cinayət mühakimə icraatında hüquqi şəxslərin iştirakının formalaşması mərhələlərinin təhlili
Authors: Mammadzada Ilhama
Published: January 2025

This article explores the historical evolution of legal entities’ participation in Azerbaijan’s criminal proceedings, distinguishing five key developmental stages. During 1923–1960, legal entities were first referenced, yet their role remained limited, and they were not considered independent subjects of criminal liability. Between 1961 and 1990, their procedural status incrementally improved, though they still lacked recognition as fully accountable parties. Following independence in 1991 and the shift to a market economy (1991–2000), the significance of legal entities grew, despite ongoing challenges in their legal integration. From 2000 to 2016, new Criminal Procedure Codes clarified the procedural roles of legal entities, but unresolved issues persisted concerning their legal protection. The introduction of Chapter LVI-I in 2016 marked a crucial turning point by officially recognizing legal entities as subjects of criminal liability, thereby enhancing the system’s effectiveness. However, the article emphasizes that further reforms are essential to fully guarantee their rights and obligations within the criminal process.
Keywords: criminal procedural role of a legal entity, legal entity in the Azerbaijani criminal process, legal entity in the criminal process, injured party, civil plaintiff, civil defendant.
Cantonese Embroidery Art Development and Technical Language Evolution-analysis Of the Transformation and Application of Nail Gold Embroidery in Fashion Design Cases
Authors: Jin Jing , Zheng Quanyue
Published: January 2025

Nail embroidery is a typical technique of Cantonese embroidery, which is dominated by gold and silver thread, combined with techniques such as nailing, winding, winding, stabbing and padding, and forms a unique skill of embroidery school. This paper tries to combine the traditional embroidery technique with the fashion design in Cantonese embroidery and discusses the development path of traditional embroidery technique from the innovative application of technology and materials, the design of fashion structure and the aesthetic level of fashion series.
USE OF IMAGE MEDIA IMPROVES STUDENT LEARNING OUTCOMES SCIENCE SUBJECTS CLASSIFICATION OF ANIMALS BASED ON THEIR FOOD TYPES IN CLASS V OF ELEMENTARY SCHOOL
Authors: Rakasita Ely , Azmi Ulil
Published: January 2025

Objective: This study aims to improve student learning outcomes on the topic of animal classification based on food type at SDN 15 Pulau Rimau, addressing the low achievement caused by traditional teaching methods. Method: A classroom action research approach was employed, utilizing scientific models and visual media to enhance understanding and engagement. The research was conducted in two cycles, each consisting of planning, implementation, observation, and reflection stages. Data were collected through descriptive analysis, in collaboration with the classroom teacher. Results: The use of scientific models and image media significantly improved student participation and learning outcomes. Observations during both cycles showed increased student engagement and a better grasp of the material. Novelty: This study contributes to the field by demonstrating the effectiveness of combining scientific teaching models with visual aids to foster active learning and improve academic performance, particularly in science education.
THE ROLE OF ACEHNESE ULAMA THOUGHT IN ISLAMIC FAMILY LAW REFORM IN THE GLOBALIZATION ERA
Authors: Salim Mahmudi Muhammad , Hamdi Muhammad Abdul Ghaffar Walid , Hidayat Taufiq , Amiruddin Amiruddin , Jani Rafsan
Published: January 2025

Objective: This study aims to explore the thoughts of Acehnese scholars on Islamic family law and their role as catalysts for inclusive and adaptive legal reform. It investigates how these perspectives address the challenges of globalization while contributing to social justice and family welfare in Aceh. Methods: The research employs a library research approach, gathering data from written sources, including books, scientific journal articles, research reports, and legal documents relevant to the subject. The study critically analyzes these sources to understand the influence and interpretation of Islamic family law by Acehnese scholars. Results: The findings reveal three key points: (1) Acehnese scholars direct their thoughts toward adapting sharia to contemporary challenges, focusing on issues such as dowry, divorce, and women's rights. (2) The main challenges in interpreting Islamic family law include reconciling traditional and modern values and mitigating the influence of globalization, which often undermines sharia understanding. (3) The scholars' perspectives positively influence the renewal of family law, evident in local policies such as Aceh Qanun and the development of more inclusive and progressive regulations. Novelty: This research highlights the innovative role of Acehnese scholars in shaping Islamic family law to address globalization's challenges. It emphasizes their contributions to fostering inclusive legal frameworks and advancing family law reforms in Aceh, which serve as a model for balancing tradition and modernity within an Islamic context.
استجابة ثلاثة أصناف من قمح الخبز لمعدلات السماد النيتروجيني المضاف بمنطقة سلوق
Authors:   كلية الزراعة سلوق قسم المحاصيل جامعة بنغازي / ليبيا, المهدي إدريس عمر , عمر شعيب محمد ,   كلية الزراعة سلوق قسم المحاصيل جامعة بنغازي / ليبيا, الشريف ادريس بلقاسم ,   كلية الزراعة سلوق قسم المحاصيل جامعة بنغازي / ليبيا
Published: January 2025

A field experiment was carried out at Agricultural Research Station, Faculty of Agriculture (Suluq), Benghazy University in 2023/ 2024 winter season to study four nitrogen fertilizer levels (50, 100, 150 and 200 kg/ ha) on growth and yield of three bread wheat varieties, i.e. Alfi, Kasy and Behooth 210. Split-plot design in three replicated was used, where nitrogen levels was randomly distributed on whole plot and varieties were allocated in sub-plot. Increasing nitrogen levels from 50 to 200 kg/ ha significantly and gradually increased all studied traits, except number of sterile plants. Behooth 210 variety had the tallest plants and spikes (111.25 and 14.58 cm), respectively, highest number of grains/ spike (79.50) and heaviest 100-grain weight (5.10 g). However, Alfi variety the highest number of sterile plants (42.41), highest grain yield and harvest index (4.90 ton/ ha and 21.87 %), respectively. Alfi variety fertilized with 200 kg N/ ha produced the highest grain yield (5.70 t/ ha), while Behooth variety fertilized with (200 kg N/ ha) produced the highest number of grains/ spike (84.93), heaviest 100-grain weight (5.87 g) and highest biological yield (26.37 t/ ha).
Keywords: Agricultural Research Station, wheat, nitrogen levels, grain yield, harvest index, Alfi, Kasy, Behooth.
Analisis Sensori Minuman Instan Ekstrak Jahe Gajah, Jahe Emprit Dan Jahe Merah
Authors: Razi Ramadhani Ar , Ariyetti Ariyetti , Kasim Anwar
Published: January 2025

Ginger is one of the herbal plants that has many benefits, especially for health. Ginger functional drink was developed in powder form so that it is more practical for consumption. The purpose of this study was to determine panelists preference for ginger extract instant drinks from 3 different types of ginger, namely: elephant ginger, emprit ginger and red ginger. Sensory assessment was done descriptively and hedonic which includes color, taste and aroma of the ginger instant drink produced. The sensory results of ginger extract instant drink were color 3.55 (like) - 3.8 (like); taste 3.05 (normal) - 3.45 (normal) and aroma 3.5 (normal) - 3.85 (like). The results showed that panelists preferred the red ginger extract instant drink.
Pengaruh Motivasi Dan Partisipasi Petani Terhadap Tingkat Keberhasilan Program Unit Pengolahan Pupuk Organik (UPPO)
Authors: Desfiansyah Rezki
Published: January 2025

The purpose of the this research is to know: (1). The Influence of Farmer Motivation and Participation on the Success Rate of the Organic Fertilizer Processing Unit Program (UPPO), (2). The Influence of Farmer Motivation on the Success Rate of the Organic Fertilizer Processing Unit Program (UPPO), (3). The Influence of Farmer Participation on the Success Rate of the Organic Fertilizer Processing Unit Program (UPPO).
This research was conducted at Farmers Group Sumber Sri Asih in Wanguk Village, Anjatan Subdistrict, Indramayu Regency in July-September 2019. Using survey method in farmer group who got UPPO Program, with questionnaire as a tool to know information from the respondent. The data used in this research are primary data and secondary data.
The results showed that: (1). The collectively, Farmer Motivation And Participation, there is a positive and significant influence on the Success Rate of the Organic Fertilizer Processing Unit Program (UPPO). (2). There is a positive dan significant influence of Farmer Motivation on the Success Rate of the Organic Fertilizer Processing Unit Program (UPPO), (3). There is a positive and significant influence of Farmer Participation on the Success Rate of the Organic Fertilizer Processing Unit Program (UPPO).
Analisis Usahatani Jambu Air (Syzygium Samarangense) Desa Mranak Kecamatan Wonosalam Kabupaten Demak
Authors: Lutfiani Dwi , Wahyuningsih Sri , Istanto Istanto
Published: January 2025

Analysis of the pomegranate guava farming business in Mranak Village provides an overview of the economic contribution of this sector to the region. This research aims to analyze the costs, revenues, income, BEP and R/C of the water guava business in Dempet Mranak Village, Wonosalam, Demak Regency. The method used in this research used a descriptive method. This research was carried out in the last post-harvest month of October-November 2023. The number of farmers involved in this research was 12 water apple farmers. The research results show that the average total costs incurred are Rp. 4,497,917/harvest/0.7 Ha on own land, the average production amount is 1,383 Kg/harvest season/0.7 Ha and the average selling price is IDR 10,000/Kg, resulting in an average total revenue of IDR 13,833,333/harvest season/0.7 Ha, resulting in an average income of IDR 9,335,417/0.7Ha/harvest season. The average production BEP calculation is 449.8/Kg/0.7Ha/harvest season and the price BEP is IDR 3,626/0.7Ha/harvest season. The price BEP and unit BEP are both smaller than the market price and production quantity. The average RC ratio for water guava farming is 3.07
Sosialisasi Perda Kota Banjarmasin Nomor 7 Tahun 2013 Tentang Kawasan Tanpa Rokok
Authors: Dewi Merdayanty  , Junaidi Junaidi  , Agus Humaidi
Published: January 2025

Banjarmasin City Regional Regulations Concerning Non-Smoking Areas is a rule made by the Government to reduce violations committed by the community, but in reality there are still many who violate these rules. In this service activity, we discuss the effectiveness and factors that occur in the field. This activity focuses on two problem formulations, namely, how effective is the Banjarmasin City regional regulation Number 7 of 2013 concerning non-smoking areas in university areas in Banjarmasin, what are the factors that influence the effectiveness of Banjarmasin City regional regulation Number 7 of 2013 concerning non-smoking areas.
Transformasi Lingkungan: Inisiatif Bank Sampah Ngudi Lestari di Kelurahan Tinjomoyo, Kota Semarang
Authors: Davin Yusuf Nasrullah  , Muhammad Rafli Al Hafidz  , Faqih Ilhamsyah  , Devina Meisyarani  , Hilyatul Karimah Azzahra  , Leni Khasanatul Farikhah  , Ajeng Putri Salokha  , Nailah Mardhiyah  , Fuji Astutik
Published: January 2025

The Ngudi Lestari Waste Bank program, located in Tinjomoyo Village, Banyumanik Subdistrict, Semarang City, is an innovative effort to address the increasingly pressing waste problem in urban environments. This waste bank serves as a center for waste collection, sorting, and processing, transforming waste into economically valuable resources and educating the community on the importance of recycling and waste management.This research used a qualitative approach with a case study method to evaluate the Ngudi Lestari Waste Bank initiative. Data were collected through observation, interviews, and documentation, then analyzed using triangulation techniques. The results indicate that Ngudi Lestari Waste Bank is effective in raising environmental awareness, changing community behavior patterns, and strengthening social solidarity. Support from the government is crucial in expanding and optimizing the program's impact. With various future development plans, this initiative is expected to become a sustainable waste management model and be adopted by other regions, as well as a concrete example for waste management solutions at the local level.
NOISE MAP MODELING FOR THE BUKVA-VILA BUSINESS ZONE IN TEŠANJ
Authors: Imamović Nusret , Kadušić Emina , Birdahić Vehid
Published: January 2025

The Bukva-Vila Business Zone is a place for various business activities and it was created as a result of preliminary spatial planning and organized development concept of the enterprising local population, in a unique area with developed infrastructure and proximity to the center of Tešanj. The development of the Zone caused the increase of the noise levels in this area. This paper presents the development of industrial noise map using data from previous monitoring of companies to determine the impact of an industrial noise on total environmental noise, and as well as, the development of a conflict noise map using results of own measurements.
CREATING A QUALITY NETWORK INFRASTRUCTURE FOR THE PURPOSE OF SUCCESSFUL BUSINESS
Authors: Redžibašić Muharem
Published: January 2025

The rapid development of technology caused many business processes to start using electronic processing of data, what implied development of local networks in many companies and organizations. Most network infrastructures have been developed incrementally, and expanded according to the needs, and mostly an ad-hoc approach was applied, without a lot of planning and taking care of security. Network implementers, in general, were no professionals, so the network issues and security risks happen often. Many pieces of today's network infrastructure have obsolete network equipment, with configured protocols that have become insecure, and physical implementation of the network is often a big collision domain. This paper will present approach, i.e., how a quality network infrastructure can be created and what are the key steps in identifying the weak points of the network infrastructure.
DECOMPOSING CASH FLOW EFFECTS ON CORPORATE FINANCIAL PERFORMANCE: A PANEL STUDY OF NIFTY 50 COMPANIES
Authors:   University of Delhi, New Delhi India, Allail Mohammad Helal , Singh Kavita ,   University of Delhi, New Delhi India, Sharma Nishi ,   University of Delhi, New Delhi India
Published: January 2025

This study investigates the relationship between cash flow components and corporate financial performance among Nifty 50 companies in India's emerging market context from 2017 to 2023. The research uses a panel dataset of 312 firm-year observations from 39 non-financial firms. It employs a log-log regression model to analyze how operating, investing, and financing cash flows affect Return on Assets (ROA) and Return on Net Worth (RONW). The findings reveal complex relationships between cash flow components and performance metrics. Operating cash flows show a negative association with ROA (-0.1494) but a positive relationship with RONW (0.2913) while investing cash flows demonstrate positive and statistically significant coefficients for both ROA (0.1095) and RONW (0.1664). Financing cash flows exhibit negative coefficients for both performance measures (-0.0809 for ROA and -0.0895 for RONW), though not statistically significant. The model's explanatory power varies between R-squared values of 0.3727 for ROA and 0.2492 for RONW. These results support Jensen's (1986) free cash flow theory and Myers' (1984) pecking order theory while extending our understanding of cash flow management in emerging markets. The findings have important implications for corporate managers in optimizing cash flow strategies and for investors in evaluating firm performance in emerging market contexts
ANALYSIS OF DIFFERENT TYPES OF HONEY TO EMPHASIZE GENETICALLY MODIFIED SEQUENCES
Authors:   Department F1, Discipline of Cellular biology and microbiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania, Curticăpean Manuela-Claudia
Published: January 2025

Food safety and consumer health protection is a particularly important aspect, always in the attention of researchers. The authentication of honey, but also its mislabelling, is one of the current challenges related to quality monitoring. Therefore, a rigorous monitoring of the different types of honey on the market is required, to ascertain whether they are properly labeled and to detect the possible presence of modified genes. The aim of this study was to analyze honey samples, to identify the possible presence of genetically modified genes, using the technique based on DNA analysis, called real-time PCR. For this purpose, ten samples of honey were analyzed. DNA isolation was performed with Quick-DNATM Plant/Seed Miniprep kit. For identification a potential presence of the genetically modified genes in the honey samples it was used a real-time PCR kit - Xpert qDetect P-35S, T-NOS and P-FMV -DNA amplification kit, that allows detection by real-time PCR of specific DNA sequences from the 35S promoter, NOS terminator and/or FMV promoter present in total DNA previously purified from honey samples. The results showed that two honey samples - M2 and M3 contain genetically modified sequences. It can be concluded that these results illustrate the importance of honey quality monitoring for the effective detection of genetically modified organisms.
Analysis of Factors Affecting The Rupiah Exchange Rate Against The US Dollar
Authors: Priyojadmiko Eko , Azizi Muhammad
Published: January 2025

This study aims to identify and analyze the main factors that influence the Rupiah exchange rate against the US Dollar. The exchange rate is an important indicator that affects various sectors of the Indonesian economy, including international trade, inflation, and foreign investment. The method used is quantitative analysis with a multiple linear regression approach, using secondary data from Bank Indonesia, financial markets, and other related sources. The results of the study indicate that internal factors, such as inflation and BI interest rates, as well as external factors, such as the Fed interest rate and global commodity prices, play a significant role in determining exchange rate fluctuations. Higher inflation and an increase in the Fed interest rate tend to weaken the Rupiah, while an increase in the BI interest rate and foreign exchange reserves strengthen the Rupiah. In addition, global commodity prices also affect the stability of the Rupiah, especially through the impact on the trade balance. This study highlights the importance of appropriate monetary policy, foreign exchange market intervention, and foreign exchange reserve management in maintaining exchange rate stability. Understanding these factors is expected to help policymakers in dealing with global market dynamics and maintaining the stability of the Indonesian economy.
Impacto del RIMPE en los emprendedores ecuatorianos: perspectivas de recaudación fiscal y desarrollo regional
Authors: Corrales Marcalla Vilma Abigail , Gancino Segura Flora Alexandra , Vizuete Achig Marcela Patricia
Published: January 2025

El Régimen Simplificado para Emprendedores y Negocios Populares (RIMPE), implementado en Ecuador en 2022, busca fomentar la formalización y el crecimiento de microempresas mediante la simplificación de obligaciones fiscales y el establecimiento de cuotas fijas según ingresos. Este régimen tiene como objetivo incrementar la recaudación fiscal y apoyar el emprendimiento. En 2023, el número de contribuyentes disminuyó un 2,97%, con variaciones significativas entre provincias. Pichincha y Guayas lideraron en recaudación, mientras que Galápagos mostró el mayor crecimiento porcentual de contribuyentes, y Esmeraldas registró descensos importantes. El análisis de correlación de Pearson realizado entre el número de contribuyentes del RIMPE y la recaudación fiscal provincial (2022-2023) reveló un coeficiente de 0,873 (p<0,01), indicando una relación positiva muy fuerte entre ambas variables. Esto sugiere que el aumento de emprendedores registrados se traduce en mayor recaudación. Sin embargo, el régimen enfrenta retos como la limitada educación tributaria, falta de apoyo gubernamental y restricciones en deducciones fiscales, que afectan especialmente a pequeños negocios. Se encarga de efectuar incentivos fiscales, simplificar trámites y fortalecer la educación tributaria para mejorar el impacto del régimen y garantizar su sostenibilidad.
新媒体时代下非遗古城文化传承创新性研究——以揭阳古城为例Innovative research on cultural inheritance of intangible heritage ancient City in the new media era: taking Jieyang Ancient City as an example
Authors: 周雅霖  , 白波
Published: January 2025

本研究聚焦于揭阳古城非遗文化的传承，采用实地调研、案例分析和问卷调查等方法。研究发现，该地区在非遗文化传播方面存在传播方式单一、目标对象不明确、创新性不足以及合作机制不健全等问题。例如，传统宣传手段局限、当地群众认知不足、宣传方式过于保守，与各方合作较少等。针对这些问题，本文提出了构建新媒体矩阵与多元化传播策略，以及以创新思维引领内容创作与运营的建议，例如创意策划、社群互动和文创产品开发。同时，本文还提出了促进古城文化可持续发展的具体措施，包括加强非遗传承保护、完善旅游设施与服务、深化合作交流以及持续监测与评估。此外，对于合作机制不健全的问题，本文建议通过提供线下实体支持和打造本土文创产品的策略加以改善，旨在为揭阳古城非遗文化的传承与发展提供有效路径。This study focuses on the inheritance of intangible cultural heritage (ICH) in the ancient city of Jieyang, employing methods such as field research, case studies, and questionnaires. The findings reveal several issues, including a lack of diversity in communication methods, unclear target audiences, insufficient innovation, and underdeveloped collaboration mechanisms. Examples include the limitations of traditional promotional approaches, insufficient public awareness among local residents, conservative communication strategies, and limited cooperation with various stakeholders. To address these challenges, the study proposes constructing a new media matrix and adopting diversified communication strategies, as well as leveraging innovative thinking to guide content creation and operations. Specific suggestions include creative planning, community engagement, and cultural product development. Furthermore, the study outlines measures to promote the sustainable development of the ancient city’s culture, such as strengthening the protection of intangible cultural heritage, improving tourism facilities and services, enhancing collaboration and exchanges, and conducting continuous monitoring and evaluation. In addition, for the issue of underdeveloped collaboration mechanisms, the study recommends providing offline support and developing local cultural and creative products as strategies to improve cooperation. These recommendations aim to offer effective pathways for the inheritance and development of intangible cultural heritage in the ancient city of Jieyang.
Seroprevalence and Associated Risk Factors of Hepatitis E Virus Infection among Pregnant Women in Akure, Ondo State, Nigeria
Authors: Oni Omowumi Oluwarantimi , Adebolu Tokunbo Tinuola
Published: January 2025

Hepatitis E virus (HEV) infection, an emerging viral disease, can lead to a high rate of fulminant hepatitis, liver failure, and an increased risk of mortality for pregnant women and fetus. This study aimed at determining the prevalence of HEV infection among pregnant women attending antenatal clinic at selected Government Hospitals in Akure city, Ondo State, in order to provide a comprehensive information of the infection on this particular group of people in the city. A questionnaire was administered to the participants who indicated their consent to participate in the study to generate socio-demographical data of the participants and the level of awareness of the infection. A total of 199 blood samples was collected from the recruited  apparently healthy pregnant women with no history of immunosuppressive diseases. Plasma of the collected blood was subjected to the analysis of Hepatitis E virus IgM antibody using capture and colloidal gold immunochromatographic double antibody assay and the positive samples were subjected to assessment of liver enzymes using standard assays. The study revealed a prevalence rate of 3.5% of Hepatitis E virus infection among the pregnant women in the study area. Out of the 3.5% that were positive for HEV, the highest percentage frequency of occurrence of the infection (12.50%) was found in the age group > 45 years while the least percentage frequency of occurrence of HEV infection (7.14%) was observed in age group 15-19 years.  Washing of hands without soap and water after toilet use, drinking of untreated well water, and eating of left-over foods were found to be risk factors that predisposed the pregnant women to HEV infection. The high level of AST and ALT in the pregnant women is an indication of liver stress. This study showed the prevalence rate of HEV among pregnant women in Akure metropolis, the level of awareness of the infection among recruited pregnant women and factors that can predispose pregnant women to the infection. There is therefore the need for appropriate health authorities to educate the public and especially pregnant women on HEV infection and factors that can predispose them to the infection.
PROJETO ELÉTRICO RESIDENCIAL PASSO A PASSO APLICADO NA PLATAFORMA WEB WOCA
Authors: Moreira Camila de Jesus , Morais Eduardo Henrique Domingos de , Jesus Aurea Messias de , Reis Alan Kardec Candido dos , Guimaraes Emerson Carlos , Borges Daniela Freitas , Castilho Deives Ferreira
Published: January 2025

O projeto elétrico residencial é uma etapa importante na construção ou reforma de uma casa. Com o avanço da tecnologia, é possível realizar esse processo de forma mais prática e eficiente através de plataformas web, como a Woca. A Woca é uma plataforma online que oferece um passo a passo para realizar o projeto elétrico residencial de forma simples e rápida. O processo começa com a seleção do tipo de projeto, como uma casa ou apartamento, e a inserção das medidas e dimensões do imóvel. Em seguida, é possível escolher o tipo de instalação elétrica, levando em consideração a potência dos aparelhos que serão utilizados na casa. A plataforma ainda oferece uma lista de materiais necessários para a instalação, com opções de marcas e preços. Além disso, a Woca conta com uma equipe de profissionais especializados em projetos elétricos residenciais que podem ser consultados caso haja dúvidas ou necessidade de orientação. Eles também oferecem suporte para o usuário durante todo o processo de criação do projeto. Um dos principais benefícios da plataforma Woca é a economia de tempo e dinheiro. Ao utilizar o passo a passo da plataforma, é possível evitar erros e retrabalhos que poderiam gerar custos adicionais. Além disso, a Woca oferece opções de preços acessíveis para a compra dos materiais necessários para a instalação elétrica. Outro destaque da Woca é a facilidade de acesso à plataforma. Como é uma plataforma online, é possível acessá-la em qualquer lugar, a qualquer hora, desde que haja uma conexão com a internet. Em resumo, a plataforma Woca oferece uma solução prática e eficiente para o projeto elétrico residencial, com um passo a passo simplificado, suporte de profissionais especializados e opções de materiais a preços acessíveis.
A IMPORTÂNCIA DO CUIDADO FARMACÊUTICO NO TRATAMENTO DA DIABETES MELLITUS TIPO I EM CRIANÇAS E ADOLESCENTES
Authors: Pereira Jhessica Karen Paula , Cabral Lívia Rodrigues , Santos Jéssica Nunes Araújo dos , Andrade Adrielle Apolinário de , Fernandes Albetiza Lopes , Diniz Daniel Carvalho , Alencar Ilzamar de Sousa Silva , Silva Jéssica de Sousa
Published: January 2025

Introduction: Childhood and adolescence are the typical periods of onset of type 1 diabetes mellitus (DM1), marked by hyperglycemia and diabetic ketoacidosis. This autoimmune disease is characterized by the infiltration and destruction of insulin-secreting cells in the islets of Langerhans by lymphocytes. The fundamental role of pharmaceutical professionals in the care of patients with DM1 is essential, their involvement encompassing the management of blood glucose levels, the recommendation of appropriate dosage regimens, the recommendation of lifestyle changes and the selection of medications based on individual needs, safety, cost and efficacy. Objective: The aim of this study was to highlight the importance of the pharmacist’s role in controlling and monitoring DM in children and adolescents.. Methodology: This was a literature review carried out using materials published in databases between 2019 and 2024. Results: The pharmacist, as a qualified professional with experience in handling and managing medicines, plays a crucial role in monitoring patients with DM. Final considerations: In addition to handling medications and monitoring treatment, pharmacists provide essential guidance on the proper use of insulin and other medications, ensuring the safety and effectiveness of treatment.
A LEITURA NO OLHAR DE PAULO FREIRE: AVENTURAS DO CADERNO VIAJANTE NA 1º SÉRIE DO NOVO ENSINO MÉDIO DA ESCOLA ESTADUAL RAIMUNDO PAZ/AM
Authors: Adorno Evilin da Silveira , Fonseca Jemima Gonçalves Pinto da
Published: January 2025

In this work, Paulo Freire's contribution to the dialogicity of the pedagogical process was verified, using the Traveling Notebook as a didactic strategy in teaching reading to students in the 1st year of High School Raimundo Paz State School. The “Traveling Notebook Project” aimed to awaken students have a taste for reading and writing based on dialogical interaction, creating something new, as those who read appropriate knowledge about the world, extracting meanings and producing new meanings. It is noteworthy that the groups were divided into 3 teams made up of 8 students who met in the classroom. A detailed qualitative approach was carried out and Paulo Freire's method on problematization was used, in a new meaning. 25 students aged between 15 and 16 participated in the research. The methodology used in this dissertation was action research.  The research allowed us to affirm that the actions developed were positive, seeking an active reader capable of expanding their reading and writing knowledge, in a pleasurable and coherent way.
Characteristics of Neurophobia Among Medical Students: A Single-Centre Study In Indonesia
Authors: Zairinal Ramdinal Aviesena , Hidayati Diah Balqis Ikfi
Published: January 2025

Backgrounds: Neurophobia is a fear of neurology among medical students. Early detection is necessary for prevention and further treatment because neurophobia will have a negative impact on patient care. The objective of this study is to investigate the occurrence of neurophobia among medical students. Methods and Materials: A cross-sectional study using the validated NeuroQ questionnaire was distributed to Faculty of Medicine, University of Indonesia (FMUI) students. Inclusion criteria are age ≥18 years, pre-clinical and clerkship students, able to read, understand, speak Indonesian and answer questions independently, and willing to participate in research. Exclusion criteria are questionnaire data that is not filled in completely. Descriptive and comparative tests were carried out to analyze variables. Results: A total of 89 FMUI students completed the questionnaire with an average NeuroQ score of 17.22 (SD 1.999). Most of the students (73 students; 82%) had a NeuroQ score ≥16 points, 32 students (36%) had neurophobia, and 41 students (46%) had marked neurophobia. Gender was not related to the total NeuroQ score (p=0.815). There was no significant difference between pre-clinical and clerkship students with the total NeuroQ score (p=0.246). Conclusions: Most students experience neurophobia. New strategies are needed to change students' perceptions of neurology.
Multidisciplinary Approach of Neonatal Intensive Care in Bam Syndrome: A Rare Case Report
Authors: Putri Humaira Tabina , Tresna Queen Choirunisa Tansa Tresna , Nugrohoputri Tsabita Aurelia , Apsari Luisa Ziesta Dian , Fatoni Syifa Annisa , Wibowo Tunjung
Published: January 2025

Bosma Arhinia Microphthalmia Syndrome (BAMS) is a very rare condition characterized by eye defects, a complete absence of nose, and hypogonadotropic hypogonadism, which is caused by a genetic mutation in the gene SMCHD1 located in chromosome 18p11. Fewer than 100 cases were reported globally over the previous century, and only a few clinical studies have discussed its occurrence and management in Indonesia. Therefore, there are no clear guidelines about the management of neonates with BAMS due to its rarity. This study reported a BAMS neonatal patient with atresia choana, microphthalmia, pectus excavatum, facial dysmorphic, unspecified hearing loss, and hydronephrosis. An MSCT scan of the patient revealed an absence of cavum nasi, undeveloped paranasal sinus, microcephaly, abnormal size of bulbus oculi sinistra, and the presence of cleft palate. This condition prompted the patient to require intensive medical support early in life due to breathing and feeding difficulties, as well as the need for several examinations on many aspects to determine the extent of the syndrome which has different characteristics for each individual. Therefore, a multidisciplinary approach is necessary to provide the most suitable management for each neonate with BAMS. This case report described the patient’s neonatal intensive care and management with a multidisciplinary team which includes a neonatologist, an ophthalmologist, an otorhinolaryngologist, a radiologist, an endocrinologist, and an oral and maxillofacial surgeon.  This study aims to improve the knowledge of BAMS patient management in the future since there are no standardized guidelines or treatment protocols, and the case is rarely studied.
Potential Application of Circulating Tumor Cell Markers to Evaluate Response to Chemotherapy in Breast Cancer Patients: A Narrative Review
Authors: Wibisana I Gusti Ngurah Gunawan
Published: January 2025

Breast cancer treatment has shifted from conventional therapy to personalized medicine based on heterogeneous and dynamic cancer biology characteristics. Cancer cells can actively spread from the primary tumor into the peripheral circulation as circulating tumor cells (CTC) to initiate cancer progression. The liquid biopsy technique, which includes repeated assessment of the number and molecular profile of CTCs, can be used to detect changes in CTC biological behavior, determine chemotherapy resistance, and predict recurrence at the molecular level. Only 3% of the CTC population, in the form of proliferating CTCs, survive and continue the metastatic process as a result of the immune system, biophysical factors, and chemotherapy. These viable CTCs can be identified through 7-Amino Actinomycin D labels, which bind to DNA in the nucleus. These CTCs have the property of cancer stemness and plasticity through the presentation of epithelial and mesenchymal markers due to the epithelial-mesenchymal transition (EMT) process, which enables CTCs to escape the immune system by expressing PD-L1 as immune checkpoint surface signals. When CTCs are still in circulation, they express MUC1, which binds to endothelium and initiates the metastatic adhesion cascade process. Using a flow cytometry method based on surface and intracellular protein markers, these proliferating CTCs can be identified using a label-dependent approach. The response to chemotherapy can be assessed by analyzing information on the changes in the number and characteristics of breast cancer CTCs based on a combination of EMT, immunological checkpoints, cancer stem cells, cell viability, and endothelial adhesion marker protein.
Artificial Intelligence Empowering Online Teaching of Chinese as a Foreign Language: Opportunities, Challenges, and Future Prospects
Authors: Mo Zengxian
Published: January 2025

This study explores the application, opportunities, challenges, and future development directions of artificial intelligence (AI) in the online teaching of Chinese as a foreign language. AI offers intelligent and personalized teaching methods, enhancing teaching efficiency and optimizing resource allocation. However, its application faces challenges such as technical limitations, teaching ethics, and privacy. The online teaching of Chinese as a foreign language has emerged in the context of globalization. Despite its development, it is constrained by issues like unstable networks. Existing teaching platforms have their own characteristics and deficiencies, and AI has varying application effects in different teaching links. The acceptance of AI by teachers and students is influenced by multiple factors. In the future, AI technology is expected to make continuous breakthroughs, and Chinese as a foreign language education will exhibit new forms such as diversified teaching content, personalized teaching methods, and intelligent teaching models. The government, educational institutions, etc. should jointly promote its development.
Leveraging Big Data Analytics and Machine Learning Techniques for Sentiment Analysis of Amazon Product Reviews in Business Insights
Authors: Moore Chethan Sriharsha , Chinta Purna Chandra Rao , Katnapally Niharika , Ja Krishna , Routhu Kishan Kumar , Velaga Vasu
Published: January 2025

Sentiment research is essential for comprehending consumer input and raising the calibre of goods and services. This study looks at the dataset of Amazon product evaluations and how sentiment analysis using ML approaches was done. Several ML methods, such as Gradient Boosting (GB), Logistic Regression (LR), Naïve Bayes (NB), and Recursive Neural Network for Multiple Sentences (RNNMS), are used in this research to analyse the sentiment of Amazon product reviews. The approach begins with preprocessing the dataset by removing punctuation, filtering stop words, and tokenising the text, followed by feature extraction using techniques like Bag of Words (BoW). The models are evaluated using the F1-score, recall, accuracy, and precision once the data is separated into training and testing sets. Among a models tested, Gradient Boosting outperforms the others with a consistent 82% in all metrics, demonstrating its strong classification ability. The outcomes show that while GB provides a highest performance, future work could explore advanced models and techniques to further enhance sentiment classification accuracy across diverse product categories.
ANALYSIS OF DRINKING WATER QUALITY AND ENVIROTMENT HEALTH RISK OF IRON (Fe) POLLUTION FROM DUG WELLS IN THE WORKING AREA OF COMMUNITY HEALTH CENTER IN OGAN KOMERING ILIR REGENCY
Authors: Suryati Eka , Maksuk Maksuk
Published: January 2025

Background: Iron is one of the metal parameters regulated in the Minister of Health's regulation regarding clean water and drinking water. Iron can cause health problems if it accumulates in the body.Methods: This study is a quantitative descriptive study with an environmental health risk analysis approach through a table-top approach evaluation to see the level of risk of heavy metal Fe in well water of residents in the working area of the Ogan Komering Ilir Regency Health Center. The study design is cross-sectional. This research was conducted in 2023 in the working area of the Ogan Komering Ilir Health Center. Results: Intake value based on the minimum Fe content in well water in adults were obtained at 0.00032 mg/kg/day, while in children it was 0.00070 mg/kg/day. The calculation results of the Fe Intake value based on the maximum Fe content in wells for adults were 0.00061 mg/kg/day while in children it was 0.00014 mg/kg/day. Meanwhile, based on the average value, the Intake value for adults was 0.00032 mg/kg/day, and for children it was 0.00070 mg/kg/day, with a Reference Concentration Dose of 0.3 mg/kg/day. The (RQ) value was obtained less than 1 for all calculations based on the intake value. Conclusion: The Fe levels in community well water in the Ogan Komering Ilir Community Health Center work area are still below the quality standard and the results of the Risk Quotient calculation in the water are still safe, but continuous monitoring by the Community Health Center is needed.
Perlindungan Hukum terhadap Pembeli Lelang Eksekusi Hak Tanggungan yang Tidak Dapat Menempati Objek Lelang Dikarenakan Adanya Perlawanan Hukum dari Debitur
Authors: Oroh Andika Natanael , Prasetyo Dedy A , Kumala Yudha Cahya
Published: January 2025

Perlindungan hukum terhadap pembeli lelang hak tanggungan memberikan kepastian hukum atas objek yang dibeli melalui lelang, yang mengakibatkan peralihan hak dari pemilik hak tanggungan kepada pembeli, tercantum dalam Risalah Lelang. Namun, dalam praktiknya, peralihan hak ini sering menimbulkan masalah, seperti perlawanan dari debitur yang mengakibatkan ketidakmampuan pembeli untuk menguasai objek lelang, serta gugatan dari pemilik awal atau pihak ketiga. Terdapat juga kemungkinan pembatalan lelang oleh pengadilan jika ada gugatan yang dapat dibuktikan di persidangan. Penelitian ini menggunakan metode yuridis normatif dengan pendekatan perundang-undangan, konseptual, analitis, dan kasus. Data yang digunakan adalah data sekunder dengan teknik pengumpulan bahan hukum melalui studi pustaka. Analisis dilakukan dengan penafsiran gramatikal dan sistematis. Hasil penelitian menunjukkan bahwa lelang eksekusi hak tanggungan dapat dibatalkan melalui putusan pengadilan jika ada gugatan pihak lain yang terbukti. Pembeli lelang yang beritikad baik seharusnya mendapatkan perlindungan hukum dari negara, baik secara preventif maupun represif. Saran dari penelitian ini adalah pentingnya kepatuhan terhadap peraturan oleh semua pihak terkait dalam proses pemberian kredit, lelang, dan penyelesaian sengketa agar perlindungan hukum bagi pembeli lelang dapat terjamin dan efektif.
Merger between Keurig and Dr. Pepper: Creating Synergy through Distribution Efficiency
Authors:   Korean Academy for Leaders of Management, Kim Dain
Published: January 2025

This case study aims to analyze how the integration between Keurig and Dr. Pepper increased distributional efficiency after 2018. The integration created synergy by way of internal supply chain restructuring, distribution network expansion, global partnership signing, digital marketing and eco-friendly management. In particular, it can be said that the increase in direct store delivery policies promoted distribution to various consumers, and the global partnership signed with the Lavaza Group further expanded the existing market share and contributed to improving consumer access. However, as awareness of environmental pollution increases, the issue of K-Cup recycling has been identified as a problem to be solved later. This case study aims to suggest that convergence between industries can create new engines for corporate growth and that strategies that arouse consumer participation in sustainable management and digital platforms are becoming increasingly important.
Optimización del portafolio de inversiones mediante los modelos de Markowitz y Blac-Litterman: un enfoque integrado para la gestión de riesgos y rendimientos.
Authors: León Landín Yoxana
Published: January 2025

Este estudio combina los modelos de Markowitz y Black-Litterman para optimizar portafolios de inversión, buscando equilibrar riesgo y rendimiento bajo diferentes condiciones de mercado. Se utiliza el modelo de Black-Litterman para ajustar los retornos esperados, integrando tanto las opiniones subjetivas de los inversores como el equilibrio de mercado (CAPM). Estos retornos ajustados son luego empleados en el modelo de Markowitz para optimizar la varianza y seleccionar portafolios. Los resultados indican que esta integración mejora los índices de rendimiento ajustado al riesgo, como las ratios de Sharpe y Treynor, en comparación con portafolios optimizados por un solo modelo. Los portafolios integrados capturan eficientemente tanto las expectativas del mercado como las opiniones subjetivas, mostrando un mejor balance entre retorno y riesgo, especialmente en mercados inciertos y volátiles. La capacidad de ajustar las estimaciones de retorno y covarianza es crucial para mantener la efectividad en tiempos de crisis económicas o cambios en políticas.
Efectos de la globalización en la contabilidad internacional de pequeñas y medianas empresas (PYMES) en Ecuador, periodo 2020-2023.
Authors: Camacho López María Elena
Published: January 2025

La investigación analiza los efectos de la globalización en la adopción de las NIIF por parte de las PYMES ecuatorianas. El objetivo general fue evaluar cómo la globalización y factores empresariales, como el tamaño de la empresa, influyen en la adopción de estas normativas. Se empleó un enfoque no experimental y mixto, utilizando encuestas y análisis estadístico con pruebas de Chi-cuadrado y correlación de Spearman. Los resultados mostraron que la globalización tiene una influencia significativa en la adopción de las NIIF, especialmente en empresas medianas y con exposición a mercados internacionales. Aunque los obstáculos financieros y tecnológicos no tuvieron un impacto significativo, la falta de capacitación y la complejidad normativa fueron barreras importantes para la implementación de las NIIF.
Impacto del gasto público en educación superior sobre el crecimiento económico en la Comunidad Andina.
Authors: Camacho Ulloa José Manuel
Published: January 2025

El estudio analiza el impacto del gasto público en educación superior sobre el crecimiento económico, la productividad laboral y la innovación tecnológica en los países de la Comunidad Andina entre 2009 y 2019. Utilizando un enfoque cuantitativo, se evaluó la relación entre el gasto en educación superior y variables como el crecimiento del PIB, la proporción de fuerza laboral con educación avanzada y el gasto en I+D. La metodología incluyó análisis de regresión lineal y correlación. Los resultados revelaron una relación negativa entre el gasto en educación superior y el crecimiento económico, además de una falta de relación significativa con la productividad laboral. Se encontró una relación positiva entre el gasto en educación superior y el gasto en I+D, lo que sugiere que la inversión educativa está impulsando la innovación tecnológica. Se concluye que es necesario mejorar la eficiencia del gasto y su alineación con las demandas del mercado laboral.
DETECCIÓN DIRECTA DE SARS-COV-2 MEDIANTE RT-qPCR EN PACIENTES REFERIDOS AL INSTITUTO NACIONAL DE HIGIENE “RAFAEL RANGEL”
Authors: Giulianna Vidalina Antonelli Giulianna Vidalina Antonelli , Aleiram Chaurio Aleiram Chaurio , Marwan Aguilar Marwan Aguilar
Published: January 2025

El método gold-estándar para la detección del SARS-CoV-2 es la RT-qPCR, sin embargo, ésta requiere de un paso de extracción y purificación previo que retrasa la entrega de resultados, especialmente en los momentos de mayor demanda diagnóstica. Con el fin de reducir el tiempo de procesamiento fueron evaluados tres métodos de extracción directa sin purificación de la muestra: buffer de lisis, calentamiento a 70°C por 10 min y 95°C por 5 minutos. Para ello, fueron seleccionadas 134 muestras conservadas de individuos con sospecha de Covid-19, referidos al INHRR durante el periodo Junio 2021-Febrero 2022, las cuales fueron procesadas por cada uno de los métodos planteados y seguidamente llevadas a RT-qPCR; los resultados obtenidos fueron comparados con el método gold estándar. En este estudio fue posible la detección directa del SARS-CoV-2 con una sensibilidad superior al 80% en los tres métodos evaluados, conservando un buen grado de concordancia con el método de referencia (k=0,79 para buffer de lisis, k=0,85 y k=0,84 para calentamiento a 70°C y 95°C respectivamente), y sin mostrar diferencias significativas (p=0,92, α=0,05) entre las variaciones de Ct obtenidos por las diferentes metodologías. La detección directa a partir de calentamiento a 70°C por 10 min es la metodología que mostró mayor sensibilidad (86,30%), estos resultados representan un hallazgo valioso para la comunidad científica del país ya que ofrece una alternativa diagnóstica que permite reducir el tiempo de entrega de resultados, contribuyendo con la contención de contagios en los puntos de mayor demanda.