bluuebunny/crossref_metadata_2025 huggingface dataset:
TreeSp2Vec: a method for developing tree species embeddings using deep neural networks
Authors: González-Rodríguez Miguel A. , Diéguez-Aranda Ulises , Ping Zhou
Published: June 2022

1. In recent years, Representation Learning (RL), a subdiscipline of artificial intelligence, has proved a valuable resource in many research fields for mapping abstract categories into numeric scales as a means to boost varied quantitative modeling tasks. Despite the up-and-coming advantages that RL could imply for managing categorical data in ecological modeling, applications in ecology are still lacking. In this study, we proposed a new method for applying RL to forest ecology, labeled TreeSp2Vec, for developing tree species numeric representations (embeddings).2. Our approach entailed a supervised species classification of individual trees using as input a set of phytocentric (morphometrics and composition) and geocentric (climate, soil, and physiography) variables derived from National Forest Inventory data and environmental cartography. Species classification was carried out using deep neural networks with several fully connected layers, an intermediate embedding layer of up to 32 dimensions, and an output layer with softmax activations.3. Among the tested neural network architectures, a multi-layer perceptron with two hidden layers of 1024 units and an embedding layer of 16 units provided the best apparent and test classification performances (Matthew’s Correlation Coefficient = 0.89). Additionally, the developed latent representations (W), or embeddings, were evaluated intrinsically by estimating their correlations with supplementary species descriptors that were not included in the training dataset. The evaluation analysis revealed some significant associations that proved the generality of the embedding model. For instance, some latent dimensions (e.g., W6 and W16) helped differentiate species general features, such as conifers vs. broad-leaved species, while other dimensions (e.g., W2 and W5) were related to forest ecosystem characteristics such as competition intensity (relative spacing index) and biodiversity (Simpson index).4. We concluded that the developed embeddings provided accurate and generalizable numeric representations of the considered tree species, which can be used as a ground for further cutting-edge forest ecology modeling approaches. Moreover, our approach is easily extendable to other ecological research areas, opening a new range of artificial intelligence applications in ecology.
Discontinuous noun phrases in Vietnamese
Authors:   , Duong Phu Sarah
Published: June 2022

Since Vietnamese is an isolating language, word order plays an important role in identifying the function of a particular word. Yet in some contexts word order may be flexible especially in the case of special information-structural settings. Discontinuous noun phrases constitute a specific case of non-canonical word order in Vietnamese. I have conducted two read-speech experiments in order to find out whether there are prosodic or intonational effects in a comparison between continuous and discontinuous noun phrases in Vietnamese. In the first experiment, speakers from the Northern dialect were recorded and in the second experiment speakers from the Southern dialect. The results showed prosodic differences in the two word order conditions in both dialects. The duration of the classifier is significantly longer (p<0.001, ANOVA calculation) in the case of discontinuous noun phrases and the rising tone (sắc) is clearly articulated as rising. In the case of continuous noun phrases, the duration of the classifier is significantly shorter (p<0.001, ANOVA calculation) and a classifier with rising tone may lose its rising property. These prosodic effects are related to prosodic boundaries. In the case of discontinuous noun phrases, the classifier constitutes the prosodic boundary, whereas with continuous noun phrases, the (right) prosodic boundary occurs further to the right. I assume that in Vietnamese there is generally a correspondence between syntactic and prosodic structure as in Selkirk (2011) and Féry (2017). This means that for example the DP hai trái cam ‘two oranges’ (two CLF orange) is matched by a prosodic phrase, thus (hai trái cam)Φ. However, when the noun cam ‘orange’ is separated from the numeral-classifier complex, the noun and the classifier form a prosodic phrase on their own: (hai trái)Φ. It can thus be concluded that intonation effects in Vietnamese are not only present when expressing sentence modality and when changing the role of function words (Đỗ et al. 1998 and Hạ & Grice 2010), but they also play a role in word order change, as in discontinuous nominal phrases. When it comes to syntactic aspects of discontinuous noun phrases, I discuss whether split constructions in Vietnamese involve movement as proposed by Trịnh (2011) or base-generation as put forward by Fanselow & Féry (2006). I argue for base-generation analysis since the second part of a discontinuous NP (remnant) may also occur outside of discontinuous noun phrases without its head noun and some discontinuous noun phrases do not have a continuous counterpart. My study confirms the connection between syntax and prosody. The two parts of the discontinuous noun phrase form their own phrases syntactically as well as prosodically.
Sustainable Tourism and Housing Development for Panggang Island, Seribu Islands Jakarta: Learning from Maldives' Sustainable Tourism Development
Authors: Tanuwidjaja Gunawan , Mustakim
Published: June 2022

In 2016, Indonesia's tourism sector contributed 4 per cent of the Indonesian Gross Domestic Product (GDP). By 2019, the Indonesian Government wants to increase the tourism contribution to 8 per cent of GDP, requiring 20 million tourist visits. Ten "New Bali" destinations have been developed by President Jokowi, including the Seribu Islands Regency. Seribu Islands, located in Jakarta Capital Region, has various potentials and problems, such as economic disparity, rising seawater levels, declining fisheries production, limited water resources, and environmental pollution. Some Neighborhood Units (Rukun Warga) in the Seribu Islands are slums, including Panggang Island. Therefore, an Integrated Kampung Improvement (Muhammad Husni Thamrin Plus Program) was proposed. This study is prepared to identify potential concepts for spatial rezoning of Panggang Island, integrating sustainable tourism and housing neighbourhood redevelopment. The research problems are how can the community create a healthier and safer home, how can the sustainable 'tourist lodge' model in Panggang Island, and what concept of spatial rezoning of Panggang Island can be proposed. To understand the integration of tourism and residential development, we conducted Case Study Research (CSR) to learn from the Maldives Islands and implemented a qualitative approach of Strength, Weaknesses, Opportunities, and Threats (SWOT) analysis for Panggang Island. Based on the SWOT, we propose a rezoning concept for sustainable Panggang Island, integrating potential tourism zones, new fisher's housing zones, polder infrastructures, utilities, and green zones. Further, in the COVID-19 Era, an additional review on personal tourism was conducted to propose sustainable tourism activities on the Panggang Island while reducing the spread of COVID-19.
Weight Reduction in Aluminum Metal Matrix Composite by Adding Copper Slag as A Reinforcement
Authors: G Rakesh
Published: June 2022

The aim of this paper is to fabricate aluminum metal matrix composite which should have less weight than aluminum and better mechanical property. Copper slag (waste from copper extraction) is taken as a reinforcement and the metal matrix composite of aluminum 95% and copper slag 5% was fabricated using the stir casting method. The particle distribution is verified by an optical microscope. Mechanical properties of the composite were calculated by conducting the tensile test, impact test, and hardness test, and the calculated values are compared with the theoretical value and aluminum.  The chemical composition of the copper slag is tested and checked with literature values. The tensile strength, hardness, and impact strength of the composite is increased when compared with base metal aluminum but the weight of the composite is less.
Afghanistan in International Opium Control Policy
Authors: Reis Pereira Paulo José , Oliveira Vieira Maria Gabriela
Published: June 2022

In this article, we propose to discuss the causes of the illegal opium market in Afghanistan from a complementary perspective to those currently present in the literature, by focusing on the international policy of the drug control system established by the UN. Using historical and qualitative analysis, we interpret the UN international conventions that permit the legal production of opium in the world in light of relevant historical events. We conclude that the international drug control regime, by responding to the political and economic interests of the main actors of the legal opioid market, has contributed to Afghanistan becoming the world’s largest illegal producer of opium.
AVANÇOS NA PRODUÇÃO E FORMULAÇÃO DE INOCULANTES MICROBIANOS VISANDO UMA AGRICULTURA MAIS SUSTENTÁVEL
Authors: Florencio Camila , Bortoletto-Santos Ricardo , Favaro Camila , Brondi Mariana , Velloso Camila , Klaic Rodrigo , Ribeiro Caue , Farinas Cristiane , Mattoso Luiz
Published: June 2022

ADVANCES IN THE PRODUCTION AND FORMULATION OF MICROBIAL INOCULANTS FOR A MORE SUSTAINABLE AGRICULTURE. The wide application of beneficial microorganisms in agriculture as inoculants to combat pests and diseases and/or to improve soil fertility and the nutrients availability for plants has been considered as an effective and more sustainable alternative than chemical fertilizers and agricultural defensives. However, it is necessary to examine all processing steps of these bio-based products under a more integrated view including the type of microorganisms and the whole production process in order to reduce dependence on synthetic chemical inputs. Here, recent developments on the production and formulation technologies of microbial inoculants and the main types of inoculants currently applied in agriculture are addressed. The different types of microbial formulations are compared with emphasis on the encapsulation technology. Moreover, the application of biofertilizers in seed coating and a new approach to apply biocomposites as fertilizers are discussed, presenting the main challenges and future perspectives to promote more sustainable agriculture practices.
Dignidad humana y deber funcional en el derecho disciplinario, bajo los principios de intimidad e igualdad en Colombia de 2010 a 2019
Authors: Paredes Mosquera Hoover Hugo , Cárdenas Castro Nubia Magaly , Paredes Londoño Aura Isabel , Buitrago González Nini Johjana
Published: June 2022

El objetivo de este artículo de investigación, es comparar las conductas establecidas como faltas disciplinarias, en los diferentes regímenes de acuerdo a la dignidad humana, y conforme a la intimidad e igualdad del servidor público en Colombia, para la cual se empleó el método mixto, utilizando las técnicas de análisis documental de la normatividad, jurisprudencia y doctrina aplicable a los servidores públicos en general y a los integrantes de la fuerza pública, también se realizó un análisis de datos proporcionados por la Procuraduría General de la Nacional, registrados en el Sistema de Información de Registro de Sanciones y Causas de Inhabilidad – SIRI, sobre las sanciones impuestas desde el año 2010 a 2019. De esta forma, se evidenció la existencia de conductas que afectan potencialmente la intimidad e igualdad del servidor público, y en mayor proporción a los uniformados de la Policía Nacional, reemplazando la función preventiva disciplinaria por la función punitiva del Estado.
Empleabilidad de las personas con discapacidad “una revisión narrativa”: alternativas desde la inclusión laboral
Authors: Agredo Silva Vicenzo Vicente , Montenegro Martínez Gino
Published: June 2022

La conceptualización de la empleabilidad representa un proceso histórico que dependiente del contexto y las necesidades toma diferentes matices, sin embargo, no involucra su aplicación en personas con discapacidad. Este articulo pretende analizar las nociones de empleabilidad y sus factores relacionados, así como presentar algunas alternativas para su aplicación en esta población, desde el enfoque de inclusión laboral. Para ello, se realizó una revisión narrativa de la literatura científica en español e inglés publicada en los últimos 10 años utilizando descriptores DeCS y MeSH, en las bases de datos Pubmed, Medline, Scielo, Scopus y Google Scholar. El concepto de empleabilidad carece de consenso, permite diversas interpretaciones y no existe en la bibliografía revisada descripciones aplicadas a las personas con discapacidad en edad de trabajar. Así, resulta la idea de generar elementos teóricos que aporten a esta construcción conceptual en favor de los usos que frente al empleo pueda tener.
Stem Cells and Congenital Heart Disease: The Future Potential Clinical
Therapy Beyond Current Treatment
Authors: Julian Katherine , Garg Nikita , Hibino Narutoshi , Jain Rohit
Published: June 2022

Congenital heart disease (CHD) is the most common congenital anomaly in newborns.
Current treatment for cyanotic CHD largely relies on the surgical intervention; however, significant
morbidity and mortality for patients with CHD remain. Recent research to explore new avenues
of treating CHD includes the utility of stem cells within the field. Stem cells have since been
used to both model and potentially treat CHD. Most clinical applications to date have focused on
hypoplastic left heart syndrome. Here, we examine the current role of stem cells in CHD and discuss
future applications within the field.
Cutaneous Hypersensitivity Reaction After Phenytoin Therapy in a Neonate:
A Case Report and Review of Literature Elucidating the Potential
Pharmacological Plausibility and Preventive Strategies
Authors: Rajendran Praveenkumar , Prabath Indumathi , Rani Jamuna
Published: June 2022

Background:

Drug-induced hypersensitivity reaction is a potentially life-threatening
condition reported among patients of different age groups. Phenytoin is a prototypic drug
prescribed for the treatment of a variety of seizure disorders. Allergic reaction to phenytoin therapy
in a newborn is relatively a rare clinical manifestation that is not frequently reported.

Objective:

The objective of this study is to report a suspected case of hypersensitivity reaction in a
newborn possibly due to phenytoin and the strategies to prevent these immune-mediated reactions.

Case Report:

An early term newborn on the 4th day of life developed erythematous rashes over the
abdominal region following phenytoin treatment for recurrent generalized tonic-clonic seizures.
Prenatal history was uneventful except for the mother had preeclampsia during the third trimester
of pregnancy. The suspected phenytoin was replaced with phenobarbitone to control seizure
episodes. Subsequently, the rashes disappeared. The baby had also suffered from skin
discolouration after phototherapy. Radiological investigations and cerebrospinal fluid culture were
performed to detect the etiology of seizures.

Conclusion:

Hypersensitivity reaction to phenytoin in newborns is a rare clinical entity but may
lead to serious lethal complications. Thus, stringent clinical monitoring of patients on phenytoin
therapy is mandatory, especially in the pediatric population.
Acute Intermittent Peritoneal Dialysis in Critically Ill COVID-19 Patients with Renal Failure: Saviour or Succourer
Authors: Varghese Benoy , Rajagopalan Arul , Arunachalam Jegan , Prasath Arun , Durai Rakesh
Published: June 2022

Background:

The COVID-19 pandemic has led to an increase in critically ill patients with renal failure, with many requiring renal replacement therapies. Unfortunately, many of them are too critically ill to tolerate intermittent hemodialysis. In the setting of limited resources, we did bedside acute intermittent peritoneal dialysis for critically ill COVID-19 patients with hemodynamic instability with or without ventilator support admitted to our intensive care unit.

Objective:

The aim of the study was to determine the outcome of intermittent peritoneal dialysis in critically ill COVID-19 patients.

Methods:

Our retrospective observational study included 91 patients with critically ill SARS-CoV2 infection and renal failure admitted to the intensive care unit of our hospital from July 2020 to September 2021, who underwent acute intermittent peritoneal dialysis.

Results:

The demographic, laboratory, and treatment parameters were compared between survivors and non-survivors. Variables, like increased mean age (49.88 vs. 59.07 years), presence of diabetes mellitus (36.4% vs. 63.8%), increased lung involvement (57.3% vs. 75.0%), mechanical ventilation (15.2% vs. 70.7%), systolic (84.3 vs. 77.5 mm of Hg) and diastolic (59.09 vs. 42.93 mm of Hg) blood pressures, were associated with poor outcomes. The use of hypertonic PD (63.6% vs. 37.9%), better urea reduction ratios (44.33 vs. 39.84), and increased PD cycles (66.52 vs. 44.26) were associated with a better outcome. Complications, like haemorrhage and peritonitis, occurred in 10.9%.

Conclusion:

PD is a cost-effective bedside RRT that can be considered an effective option in critically ill COVID-19 patients. Good urea clearance, hemodynamic stability, and minimal resource requirements are also the features that favour peritoneal dialysis.
ASEAN Vision 2020: The Implementation of Cooperation on Food Security
Authors: Purwanti Asih
Published: June 2022

This paper examines the implementation of the ASEAN Vision 2020 in cooperation on food security. The ASEAN Vision 2020 stated that ASEAN will strengthen their cooperation to enhance food security and international competitiveness of food, agricultural and forest products, to make ASEAN a leading producer of these products, and promote the forestry sector as a model in forest management, conservation and sustainable development. ASEAN had built a well-established framework of cooperation on food security. The establishment of the ASEAN Food Security Information System (AFSIS) was praised as an ASEAN achievement in enhancing the cooperation in food security. Although, compared to the objectives of regional economic cooperation and military security mechanism, the objective in strengthening the cooperation on food security remains less significant within the ASEAN's discussions. The question is then, by conducting numerous frameworks of cooperation, did ASEAN excel to achieve the objectives in ASEAN Vision 2020 in the sphere of food security? This paper argues that ASEAN had successfully delivered some positive achievements in the scope of regional cooperation in food security areas. However, to some extent, some ASEAN state-members are still struggling with problems related to food security, particularly regarding food accessibility. The ASEAN growing market brings about a challenge for food supply and greater pressure for the association to ensure environmental sustainability in the region. Regarding its goals within the scope of ASEAN Vision 2020, the association mostly focused on how to achieve their deeper economic integration. In the area of food security, ASEAN has managed to set up a foundation for further regional cooperation under the framework of the ASEAN Community Vision 2025 and ASEAN Vision 2040.
Preventing Terrorism by Strengthening Community Based Ecosystem in Bali Province
Authors: Indraswari Firstyarinda Valentina , Wiswayana Wishnu Mahendra , Setiawan Arief , Siahaan Krisda Thezza Lourencya , Nanda Ni Putu Rianti Sukma
Published: June 2022

Bali Bomb on 2002 becomes the first and the entry point of terrorism issues in Indonesia. It has devastated more than 200 people lives and damage the overall image of Bali as the paradise site in the world and Indonesia as a secure state. Since then, the local government try to protect the potential of terrorist attack. With its indigenous, the local government not only optimizing its agencies but also build a cooperation with the local structure of governance which has built before Indonesia exist. This paper seeks to analysis the collaboration works of these actors to maintain the stability and secure condition in Bali, especially from the terrorism issue. The research conducted through qualitative method, using interview keys person as the main references and official documents, journals, articles, databases as the supporting resources. By using the concept of the role of concentric circle of society in preventing terrorism, this research found that there is systematic communication and coordination between the government agencies and local communities in preventing the terrorism action. And by having a periodic, continuous communications, coordination, and build a controlling mechanism, amongst local government agencies such as Kesbangpol, FKPT, Babinsa, RT/RW staffs, and local actors such as Village Structure of Pakraman, Pecalang, and FKUB, they can create almost a comprehensive ecosystem to protect Bali island from the threat so far. Since 2005 there is no terrorism activity detected in this Island. Another interesting finding from this ecosystem is that this local wisdom system so far does not bring any resistance from the society and trust building among them are getting stronger.
Biodegradation Potential of Phenol and Toluene by Marine Staphylococcus pasteuri Isolated from the Red Sea, Saudi Arabia
Authors: Basingab Fatemah S.
Published: June 2022

Hydrocarbons including phenol and toluene are considered as the major source of energy and raw material of different industrial products. Although toluene and phenol have various beneficial applications, many studies reported the massive negative impacts of these contaminants on the environment and on human health. This study aims to provide an assessment of biodegradation potential of Staphylococcus pasteuri isolated from the industrial area at the coast of Red Sea, Jeddah, Saudi Arabia. From 29 isolates, a strain, that exhibits a notable growth on mineral salt medium supplemented with phenol and toluene as a sole carbon source, was chosen for further investigation. Different optimization conditions have been examined for optimal degradation; two concentrations of phenol and toluene (0.5% & 1.0%) and different incubation temperatures. Growth assessments was measured by optical density (OD) of phenol and toluene using spectrophotometer. Maximum OD for phenol and toluene: (ODmax= 0.787) and (ODmax= 0.969) compared to the abiotic control of (ODmax= 0.152) and (ODmax= 0.182) respectively. Degradation of phenol and toluene was also measured using high performance liquid chromatography (HPLC). In addition, molecular identification of the isolates was carried out using 16S rRNA analysis highlighted the isolated strain is Staphylococcus pasteuri (strain ATCC 51129) with the accession number (NR114435). This promising strain ATCC 51129 can be used in further biotechnological applications including oil biodegradation processes.
Validity and Reliability of the Turkish Version of the COVID-19-Impact on Quality of Life Scale
Authors: Ökten Çiğdem , Gezgin Yazıcı Havva
Published: June 2022

The objective of this study was to adapt the COVID-19-Impact on Quality of Life (COV19-QoL) scale for Turkish individuals and to determine its validity and reliability.

Materials and Methods. This methodological study was conducted between December 25, 2020 and January 10, 2021. The research was conducted online and included 485 participants who completed a socio-demographic questionnaire, the COV19-QoL scale and the Duke Health Profile (DUKE) on Google Forms. Back translation was used for the Turkish version of the COV19-QoL scale. Language and content validity of the scale were found to be acceptable.

Results. Ten experts were consulted regarding content validity of the scale. The results, item content validity of 0.95 and scale content validity of 0.95, indicated excellent content validity. Explanatory factor analysis found one principal structure with a total variance of 59.449%. The Cronbach’s alpha internal consistency coefficient was 0.86 for the scale. A statistically significant moderate negative correlation was found between the participants’ COV19-QoL scale score and their general health score on the DUKE (r = − 0.384; p < 0.01).

Conclusions. This study found that the Turkish version of the COV19-QoL scale is a valid and reliable instrument for assessing the effects of the COVID-19 pandemic on the Turkish population’s quality of life.
Sharing intelligence culture
Authors: Cline Lawrence
Published: June 2022

United States (U.S.) civilian and military intelligence services increasingly have engaged with local intelligence services, either in an advisory role or direct coordination or liaison. In many cases, the intelligence officers have tended to try to remake the local intelligence services in the image of U.S. intelligence structures and procedures, with these efforts rather futile in most cases. One factor that has led to considerable frustration and potential failure has been a lack of understanding of the culture of local intelligence systems.  Understanding both the subtleties of an area’s social norms and mores, and the bureaucratic and historical cultures of other intelligence services remain critical factors in long-term success. Using case studies of environments in which established intelligence services have worked with emergent intelligence agencies, this paper examines the requirements for incorporating both larger cultural approaches and detailed knowledge of other intelligence bureaucracies.
Would artificial intelligence make strategy ‘less human’?
Authors: Hodgins Julia
Published: June 2022

This article discusses the influence of artificial intelligence (AI)—specifically Narrow AI—in the formulation of strategy arguing that there is not a straightforward answer to the question posited in the title. The Impact of Narrow AI in strategic decision-making will not fundamentally alter the nature of strategy due to the impossibility to program human faculties such as rationality and intentionality. Notwithstanding, the article concludes that ethical issues in the global environment will sustain the basis of strategy primarily as a human and political activity for the foreseeable future. Firstly, this piece reviews overarching definitions. Secondly, it discusses how Narrow AI affects strategy’s formulation through the predictive power already developed; three illustrative examples substantiate the elaboration. Thirdly, it discusses how ethical factors limit Narrow AI’s influence at the core of strategy so that it remains a human activity first and foremost. Discussions related to tactical applications of AI—for example, drones—are out of the scope of this analysis.
Magnetic resonance imaging in the diagnosis of malignant gynaecological tumours
Authors: Ferenc Thomas , Popić Jelena , Vidjak Vinko
Published: June 2022

Magnetic resonance imaging (MRI) is a widely used imaging modality that depicts detailed information regarding morphological and functional characteristics of the human body. It is routinely used in gynaecologic oncology for female pelvis imaging because of the high spatial and soft-tissue contrast resolution. Furthermore, MRI is an important diagnostic tool for the assessment of common gynaecological malignancies - endometrial carcinoma, cervical carcinoma and malignant ovarian tumours. Novel technical developments enabled the multiparametric MRI approach in the diagnosis of respective tumours combining T1-weighted (T1W) sequences, T2-weighted (T2W) sequences, diffusion-weighted (DW) sequences with apparent diffusion coefficient (ADC) values and dynamic contrast-enhanced (DCE) sequences. With highlighted novelties, MRI importance ranges from tumour detection to treatment response monitoring and early recurrent disease evaluation. This review discusses the value of MRI in the diagnostic assessment of the common gynaecological malignancies with an¬¬ emphasis on tumour staging.
Primjena umjetnosti u dječjoj psihoterapiji kroz prizmu psihoanalitičkih korijena kreativnosti
Authors: Tomašić Lea , Radovančević Ljubomir
Published: June 2022

U ovom radu autori razmatraju psihoanalitičke temelje likovne psihoterapije. Kreativnost izvire u nesvjesnom i reprezentira unutarnje konflikte, stoga likovno stvaralaštvo može poslužiti kao jedinstven prozor u unutarnji svijet bolesnika te dodatno unaprijediti psihoterapijski proces psihodinamski orijentirane terapije. Na temelju vlastitog kliničkog primjera te primjera iz literature prikazana je korist art-terapije u praksi dječje psihoterapije. Cilj rada je, kroz sintezu starije i novije literature, podsjetiti kliničare na veliku praktičnu iskoristivost art-terapije kao psihodinamski orijentirane psihoterapije, koja je u današnjem vremenu mnogobrojnih psihoterapijskih pravaca neopravdano pozicionirana kao psihoterapijska opcija drugog izbora.
Challenges in the diagnosis of mandible metastasis
Authors: Gudelj Sara , Belušić-Gobić Margita
Published: June 2022

Aim: To report the clinical course of a patient with long-lasting pain and swelling of mandible who was subsequently diagnosed with large cell neuroendocrine carcinoma (LCNEC) of the lung and to point out the importance of expanding the diagnostic approach. Case report: A 61-year-old female patient was referred to the Department of maxillofacial surgery due to severe pain in the area of temporomandibular joint (TMJ) spreading to the upper and lower jaw. Physical examination revealed tenderness, swelling and pain of the preauricular area. MR imaging showed anterior disc displacement with degenerative signs on the left side which indicated arthrocentesis. It resulted with clinical improvement that lasted for 1.6 years. Newly made orthopantomogram revealed unclear changes of the left mandibular corpus. Due to the unclear diagnosis patient underwent biopsy on two occasions, which excluded IgG4 disease, other rheumatology and hematology diseases as well as the tumor. Five years after the initial admission, the patient stated the occasional dyspnea and cough leading to administration of the chest RTG, showing visible round mass in the upper left lobe of the lung. PET/ CT showed accumulation of radiopharmaceutical substance in the corresponded area, affected regional and distant lymph nodes and accumulation within mandible. Somatostatin receptor scintigraphy confirmed the diagnosis, which may indicate the possibility of distant malignancies. Wedge resection of the lung mass was performed and pathohistological examination confirmed the large-cell neuroendocrine carcinoma (LCNEC) stage 3. Chemotherapy was administrated. Patient referred to an emergency medical tract due to the threatening cardiac tamponade and died 11 days after. Conclusions: Mandibular metastases are often presented by atypical signs and symptoms and often present the first sign of the malignant disease. Broad spectrum of examinations must be performed in order to prove or exclude distant malignancies so the best therapy option can be provided.
The extension of hepatocellular carcinoma into the inferior vena cava and right atrium
Authors: Morić Nikolina , Miletić Damir , Matana Kaštelan Zrinka , Fučkar Čupić Dora , Milić Sandra , Mijandrušić-Sinčić Brankica
Published: June 2022

Cilj: Prikazati bolesnika s hepatocelularnim karcinomom koji je izravno invadirao desni atrij, a inicijalno se prezentirao bezbolnom žuticom i kardijalnom insuficijencijom. Prikaz slučaja: Na Zavod za gastroenterologiju zaprimljen je sedamdesetsedmogodišnji bolesnik zbog bezbolne žutice i kardijalne insuficijencije. U fizikalnom statusu uočeni su edemi obiju potkoljenica i natkoljenica te hepatomegalija. Laboratorijskom analizom utvrđene su povišene vrijednosti kreatinina u serumu, ukupnog bilirubina, jetrenih enzima te produženo protrombinsko vrijeme i aktivirano parcijalno tromboplastinsko vrijeme. Nativna snimka abdomena pokazala je uredan nalaz. U daljnjoj obradi učinjen je ultrazvuk abdomena na kojem je prikazana uvećana jetra, nepravilnije površine, difuzno hiperehogena, inhomogena, bez vidljivih fokalnih lezija uz proširenje intrahepatičnih žučnih vodova. Test na markere hepatitisa B i C bio je negativan. Zbog razjašnjavanja uzroka bilijarne opstrukcije indicirana je magnetska rezonancija abdomena i magnetnorezonantna kolangiopankreatografija (MRCP). Otkrivena je infiltrativna tumorska tvorba koja opsežno zahvaća žučne vodove, invadira donju šuplju venu i direktno prodire u desni atrij. Širokoiglenom biopsijom i patohistološkom analizom dijagnosticiran je hepatocelularni karcinom (HCC). Tijekom hospitalizacije ordinirana je kardijalna terapija, niskomolekularni heparin, supstitucija albumina i antibiotska terapija zbog infekcije bakterijom Clostridium difficile. Usprkos intenzivnom liječenju pacijent je preminuo s kliničkom slikom višeorganskog zatajenja. Zaključak: Izravna penetracija HCC-a u desni atrij rijedak je entitet. U bolesnika koji se prezentiraju bezbolnom žuticom uz negativan nalaz ultrazvuka, potrebno je proširiti slikovnu dijagnostiku na magnetsku rezonanciju i MRCP zbog superiornosti u procjeni bilijarnog stabla. Iako je žutica rijetka prva manifestacija hepatocelularnog karcinoma, ne treba isključiti taj entitet, posebice u bolesnika s jetrenom cirozom.
Dubinska mozgovna stimulacija i esencijalni tremor u pacijenta starije dobi s izraženom atrofijom mozga
Authors: Radović Klara , Vuletić Vladimira
Published: June 2022

Cilj: Prikazati slučaj pacijenta s medikamentozno refrakternim esencijalnim tremorom kod kojega je duboka mozgovna stimulacija dovela do uspješne kontrole tremora i značajno popravila kvalitetu života unatoč starijoj dobi, izraženoj atrofiji mozga, perioperacijskim i poslijeoperacijskim komplikacijama. Prikaz slučaja: Muškarac u dobi od 72 godine došao je na drugo mišljenje zbog dugogodišnjeg bilateralnog tremora ruku, vođenog kao Parkinsonova bolest, koji mu je onemogućavao svakodnevno funkcioniranje. Fizikalnim i neurološkim pregledom utvrđen je posturalni i akcijski tremor, bez bradikineze i povišenog tonusa. Magnetska rezonancija mozga pokazala je atrofiju, a Dopamin Active Transfer scan i laboratorijske pretrage bili su uredni. Postavljena je dijagnoza esencijalnog tremora. Tijekom dvije godine pacijent je u terapiji uzimao propranolol, klonazepam, primidon te topiramate, što nije pokazalo učinka. Detaljnom evaluacijom multidisciplinarnog tima indicirana je duboka mozgovna stimulacija ventralne intermedijarne jezgre talamusa bilateralno. Međutim, dok je donosio odluku o zahvatu, u godinu dana pacijent se kognitivno pogoršao. Stanje se intraoperacijski kompliciralo visokim vrijednostima krvnog tlaka. Poslije operacije pacijent je bio smeten, s halucinacijama, što je najvjerojatnije uzrokovano hipertenzivnom encefalopatijom. Za vrijeme boravka na klinici modificirani su stimulacijski parametri i određena je kronična medikamentozna terapija. Unatoč pokazateljima da konačni ishod duboke mozgovne stimulacije možda neće biti dobar, tremor je manji i kvaliteta života ovog pacijenta značajno je bolja. Zaključak: U razmatranju pacijenta za duboku mozgovnu stimulaciju nužna je temeljita individualna multidisciplinarna evaluacija. Pažljivim perioperacijskim i poslijeoperacijskim praćenjem i prilagođavanjem stimulacija uz ispravno medikamentozno vođenje može se povoljno utjecati na ishode duboke mozgovne stimulacije kod rizičnih pacijenata. Za vrijeme operacije treba strogo kontrolirati krvni tlak jer on može uvelike zakomplicirati stanje.
A rare case of median nerve intraneural hematoma after stenting of right iliac artery
Authors: Pavić Predrag , Crkvenac Gregorek Andrea , Figl Josip , Premužić Meštrović Ivica , Perkov Dražen , Slišković Ana Marija , Vrkić Kirhmajer Majda , Brižić Ivan , Meštrović Tomislav
Published: June 2022

Aim: Brachial artery access is an alternative approach to endovascular interventions when access to the femoral, radial, or ulnar arteries is not feasible, but it carries higher risk of periprocedural complications than other approaches, including median nerve injury. Nerve injuries can occur by direct puncture or by compression, with hematoma being the most common cause. Sometimes the compartment syndrome can accompany the direct nerve injury, masking the signs of a nerve dysfunction. Case report: We present a patient with a false aneurysm of brachial artery, surrounding soft tissue hematoma with volar arm and forearm compartment syndrome and a simultaneous median nerve intraneural hematoma caused by a direct punction. The combination of injuries occurred after brachial artery access for endovascular treatment of bilateral iliac artery steno-occlusive disease. The patient was successfully treated by fasciotomy, arterial sutures, and nerve decompression via paraneuriotomy. Conclusions: Intraneural hematoma caused by direct puncture can be masked by concomitant compartment syndrome. Emphasis should be put on prevention, early recognition, and timely surgical treatment of intraneural hematomas, especially those accompanied by fascial compartment syndrome after endovascular interventions.
Art as an assistive method in diagnosing schizophrenia in children and adolescents
Authors: Mrak Maja , Belčić Sara , Rački Valentino , Petrić Daniela
Published: June 2022

Aim: To report the clinical courses of four adolescent patients, who developed childhood-onset schizophrenia and where art had a vital role in diagnosing schizophrenia, monitoring their clinical state and progression. Case report: All of the patients had several diagnoses throughout childhood; however, the final diagnosis was made with the help of art therapy. Following the changes in the content of our patients' drawings enabled us to notice the changes in their quality of life, functioning, and efficacy of therapy. Some of the patients specified that throughout the drawing process, they felt more satisfied, “better” and not „haunted„ by their hallucinations. This acknowledgment assured us that creative expression through art is an appropriate approach for them. It also strengthened the therapeutic relationship with our patients and encouraged us to understand their disease and make better decisions about their treatment. Conclusions: We propose art as an assistive method in diagnosing schizophrenia. Art can break down communication barriers and can also serve as follow-up method for children and adolescent patients with schizophrenia.
Comforting the Information and Economic Environment of the Enterprise within the Framework of the Strategic Management Paradigm
Authors: Veretyokhin A. V.
Published: June 2022

Relevance. To be successful, enterprises need a comfortable information and economic environment. The importance of state regulatory policy increases to achieve a favorable business climate. This is due to the limited resources of some Russian businesses and COVID-19 impact.

The purpose is within the framework of the paradigm of strategic management, consider the activities to create favorable information and economic conditions for enterprises.

Objectives: analyze information and economic systems to support enterprises as a management result to ensure a comfortable business environment.

Methodology. The author uses methods: posteriori analysis, synthesis, comparison, generalization, classification and data visualization.

Results. In the context of digital transformation, the relationship and mutual influence of favorability and informativeness are clearly manifested in the enterprise environment. The strategic management of economically developed countries confirms the possibility of simultaneous implementation of the state development strategic goals: "comfortable business environment" and "informatized society". This experience should be taken into account in regional management when setting goals, developing and implementing appropriate comfort measures. In this study, the author examines the enterprise comfort environment within the strategic management paradigm framework on the example of the Republic of Crimea. Two separate systems of enterprise support exist in the Republic of Crimea. The available regional information resources are not convenient enough.

Conclusion. The goals of operational management on the comfort of the business environment and the digitalization of the economy are fundamentally interconnected at the regional level. Their achievement is a single process.
Efecto de la progesterona plasmática en la competencia para el desarrollo embrionario in vitro de vacas Bos taurus taurus y Bos taurus indicus
Authors: Narváez Bedoya Héctor Javier , Da Silva Fontes Reginaldo , Campos de Carvalho Bruno , Varella Serapião Raquel , Oliveira Clara Slade , Dos Reis Camargo Agostinho Jorge
Published: June 2022

Diversos estudios han comprobado que la progesterona tiene un efecto directo en la calidad ovocitaria y el desarrollo inicial embrionario. El objetivo de este estudio fue evaluar el efecto de la concentración de la progesterona (P4) plasmática en el desarrollo de embriones in vitro en vacas de raza Bos taurus taurus (Holstein) y Bos taurus indicus (Gyr). Se utilizaron vacas Holstein y Gyr multíparas, presincronizadas con la aplicación de dos dosis de D-cloprostenol con intervalo de once días. Posteriormente, se distribuyeron en uno de tres grupos experimentales inducidos a diferentes niveles plasmáticos de progesterona. El grupo control fue sincronizado utilizando únicamente D-cloprostenol sin progesterona exógena, el grupo progesterona baja recibió un implante auricular de norgestomet de segundo uso y al grupo progesterona alta se le aplicaron dos implantes auriculares de norgestomet nuevos. Los resultados evidencian que la concentración plasmática de progesterona fue significativamente diferente (P < 0,05) tanto para las vacas Holstein (0,22 ± 0,15, 2,23 ± 0,17 y 5,32 ± 0,22 ng/mL) como para las vacas Gyr (0,24 ± 0,19, 2,05 ± 0,17, 4,85 ± 0,20 ng/mL) entre los grupos control, progesterona baja y progesterona alta, respectivamente. Las vacas Gyr presentaron diferencia (P < 0,05) en la tasa de clivaje del grupo progesterona baja en relación con los grupos control y progesterona alta (87,9 % ± 0,11 vs 77,5 % ± 0,13 y 76,4 % ± 0,10, respectivamente) y en la variable tasa de blastocistos del grupo progesterona baja (48,3 % ± 0,16) en relación con el grupo control (35,8 % ± 0,10) y el grupo progesterona alta (30,4 % ± 0,20). Se concluye que la progesterona tuvo efecto sobre el desarrollo embrionario en vagas de raza Gyr, el cual no se evidenció en las vacas de raza Holstein.
The Potential for Using Extended Reality Technology in Interdisciplinary Case Discussions and Case Planning in Stereotactic Radiosurgery: Proof-of-Concept Usability Study (Preprint)
Authors: Chidambaram Swathi , Palumbo Maria Chiara , Stifano Vito , McKenna John , Redaelli Alberto , Olivi Alessandro , Apuzzo Michael , Pannullo Susan
Published: June 2022

BACKGROUND

Extended reality (XR) is a term that captures a variety of techniques, such as augmented reality (AR) and mixed reality (MR), which allow users to interact with virtual models in real time. This technology has an emerging role in several applications within neurosurgery. XR can be useful in enhancing how radiosurgical cases are planned. Multidisciplinary team (MDT) review is an essential part of the radiosurgery case planning process; during case discussions, patient images are reviewed, usually in 2D or 3D modifications. The current commercially available platforms for this review need improvement.

OBJECTIVE

We describe a novel visualization application, titled “NeuroVis” by our development team, which uses an XR Microsoft HoloLens headset to provide an interactive 3D visualization of a patient’s neuroanatomy in stereotactic surgery (SRS) case planning discussions.

METHODS

We present examples of 6 common radiosurgery indications to demonstrate the utility of NeuroVis to solve common visualization hurdles in MDTs.

RESULTS

The utility of NeuroVis is demonstrated through 6 common brain tumor SRS cases as a proof-of-concept illustration of the utility of NeuroVis to enhance radiosurgery case discussion by improving visualization of the standard neuroimaging used in radiosurgery treatment planning by MDTs.

CONCLUSIONS

The NeuroVis application provides several interactive features that produce an enhanced ability to place participating members of an interdisciplinary treatment team on the same visualization plane. This technology, by facilitating team discussions and case review, has the potential to improve the efficiency, efficacy, and safety of radiosurgery treatment planning and, as a result, to optimize patient care.
Socio-Economic Culture of Backward Communities: An Educational Achievement of Dalit Students
Authors: Khanal Dr. Uttam , Prasad Paudel Dr. Gyanendra
Published: June 2022

The Dalit community is a backward class, due to socio-economic and educational reasons. To providing equal opportunities in education but the problems also rised, if is not done, it will be difficult to achieving educational goals and opportunity of social change. Increasing the economic access of the Dalit community will lead to participation in development and inclusion of their children in education. The problems are expressed by educational progress of Dalit students due to Poverty, lack of consciousness, large number of families, landlessness, unemployment, lack of educational scholarships, lack of agricultural and business loans, lack of schools near slums, high fees, inferiority complex, traditional social norms, discrimination against children, wasteful spending, relocation and falling mentality. Due to this, governmental and non-governmental organizations have helped to Dalit parents in their economic and social development through Dalit oriented programs. The enrollment rate of basic level is 92% as per the national policy of the government and 8% of children are out of school according to government statistics and 25% out of school according to non-government data, the challenges of educational progress of Dalit children are still acute.
Neural Networks in the Covid-19 Era
Authors: Lirios Cruz Garcia
Published: June 2022

Objective. From the review of the theories of the cycle of violence, gender violence and the social construction of masculine and feminine identities.Methodology. Carried out a non-experimental, exploratory and descriptive study with a nonrandom selection of students a public university with the aim of establishing a balance and a prospective expectation of violence.Results. The results show that of synaptic weights are explained by incoming, and outgoing latent layers on the pre-contemplation of violence, contemplation of aggressive relationships and personal change. Conclusion. Lines alluding to the kind of relationship research, negotiation and consensus decision making to warn couple conflicts.
Views about Balance of Multiple Interests in the Regulation of Anti Unfair Competition Law on Enterprise Data Crawling
Authors: Xia Yijing
Published: June 2022

Rapid innovation and widespread application of information and digital technologies encourage the continual growth and reconstruction of classic business models and market operation behaviors. The Internet economy has induced many new sorts of unfair competition while stimulating entrepreneurship and unleashing technological innovation dividends. Data crawling consumes a significant amount of Internet traffic because it is a cost-effective data collection strategy. It not only encourages data sharing, but it also makes unfair competition regulation more difficult. We should pay attention to assessing difficulties from the standpoint of interest concerns in the regulation of data crawling under the Anti-Unfair Competition Law, and completely measure whether it harms the interests of operators, customers, and social public interests. We can also use the method of interest measurement to coordinate the interest relationship in order to keep the competitive order and balance multiple interests.