bluuebunny/crossref_metadata_2025 huggingface dataset:
RELATIONSHIP OF POST-OPERATIVE INOTROPIC USE AND MORTALITY IN CABG PATIENTS WITH RADIAL GRAFTS
Authors: DAR FN , YUNUS A , NIAZ MN
Published: September 2023

This retrospective analysis aimed to assess the effect of post-operative use of inotropic support on the long-term mortality rates of coronary artery bypass graft (CABG) patients who had undergone radial grafts. Inotropic drugs are frequently administered to improve heart function after surgery, but their impact on long-term survival is still controversial. The primary objective was to compare the 10-year mortality rates between patients who received post-operative inotropic support (Group A) and those who did not (Group B). We also sought to determine whether inotropic infusion correlated with improved or worsened long-term survival. A total of 80 participants were retrospectively analyzed, with Group A consisting of 18 individuals who received inotropic support and Group B comprising 62 individuals without such support. Demographic and clinical characteristics, including age, gender, comorbidities, clinical parameters, ejection fraction, New York Heart Association (NYHA) functional class, and 10-year mortality rates, were assessed and compared between the two groups. Kaplan-Meier survival analysis was done to assess the survival benefits. The analysis revealed no significant difference in 10-year mortality rates between Group A and Group B, with an insignificant p-value of 0.987. The Kaplan-Meier survival analysis and log-rank test further supported this finding, indicating no significant relationship between the absence of inotropic infusion and increased survival chances. These results suggest that post-operative inotropic support may not significantly influence long-term survival. Inotropic infusion may not be necessary for improving or worsening 10-year survival rates in surgical patients. While this retrospective analysis provides valuable insights, further research, particularly larger prospective studies, and randomized controlled trials, is needed to validate these findings and offer more conclusive guidance regarding the use of inotropic agents in post-operative care.
Prinsip Cedera dalam Hubungan Kebebasan dan Otoritas Menurut John Stuart Mill
Authors: Yuda Pramana Oktavianus M.
Published: September 2023

Tulisan ini menelaah dinamika tegangan antara kebebasan dan otoritas dalam kehidupan politik. Menemukan prinsip untuk menganalisis tegangan antara keduanya sehingga kehidupan politik tidak jatuh dalam salah satu kutub atau ekstrem. Dalam On Liberty (2003 [1859]), Mill menyatakan perjalanan sejarah manusia dicirikan oleh pertarungan antara kebebasan (liberty) dan otoritas (authority). Dalam pertarungan itu, Mill menaruh perhatian pada kebebasan yang selalu berada dalam tegangan berhadapan dengan otoritas. Mill menyoroti batas yang tepat bagi pelaksanaan otoritas, sebab otoritas yang melampaui batas menjadi ancaman bagi kebebasan. Untuk menganalisis tegangan antara kebebasan dan otoritas, Mill mengajukan prinsip cedera (harm principle). Prinsip ini menegaskan bahwa satu-satunya tujuan pembatasan kebebasan adalah untuk mencegah cedera pada orang lain.
Az élet megformálásának kísérletei Lukács György fiatalkori esszéiben
Authors: Erőss Réka
Published: September 2023

Lukács György alkotói korszakának első, ifjúkori szakaszában (1903–1918) az irodalomkritikát használja esztétikai, kultúrfilozófiai és metafizikai-egzisztenciális problémák kifejtésére. Az ebben a korszakban íródott esszék, melyeket Lukács találóan kísérleteknek nevez, olyan kérdések köré szerveződnek, mint a művészet és az élet egymáshoz való viszonya, a kultúra lehetőségei és az alkotó ember életidegensége. Ezek pedig részét képezik egy tágabb problémafelvetésnek, amely úgy fogalmazható meg, hogy hogyan lehet formát adni az életnek. A megformálás etikai parancsként működik, a sokféleség egységbe fogására, az „életanyag alkotó elrendezésére” szólít fel. A fiatal Lukács élesen bírálja a korabeli kultúrát, mert a formaadó törekvés nem jut benne érvényre. Ugyanakkor a gondolati konstrukcióként létező forma és az empirikus élet közt tételezett hierarchia, melyben az élet pusztán a megformálás anyagaként értelmezhető, legalább annyira problematikus, mint az általa bírált esztétikai kultúra.
Történelem, filozófia, elkötelezettség. Lukács György az értelmiség szerepéről
Authors: Budai Gábor
Published: September 2023

Tanulmányomban annak próbálok utánajárni, miként vélekedett Lukács György az értelmiség társadalmi funkciójáról, különösen ami a történelem által felkínált alternatívák közötti választás morális terhét illeti. Ehhez két olyan írását hívom segítségül, amelyben a modern értelmiség általa legfontosabbnak tartott szerepéről kívánt számot adni: az egyik az 1919-ben megjelent „A szellemi vezetés kérdése és a »szellemi munkások«” című cikk, a másik pedig az 1933-ban született „»Szakadék« Nagyszálló” című tanulmány. Ezekből jól kivehetően Lukács az értelmiséget különleges társadalmi „képződménynek” tartotta: olyan rétegként kezelte, amely a történelem során soha nem szervesült (mert nem is szervesülhetett) egységes osztállyá, mégis a világ sorsának alakulása szempontjából meghatározó jelentőségű szereppel, valóságos történetfilozófiai küldetéssel bír.
A Párt és a Munka. Szempontok Lukács György filozófiájának szisztematikus-történeti kutatásához
Authors: Forczek Ákos
Published: September 2023

Vizsgálódásom fókuszában a Történelem és osztálytudat „pártmetafizikája” áll. A „Módszertani megjegyzések a szervezeti kérdéshez” című kötetzáró írást szoros értelemben vett filozófiai szövegként olvasom – ami nem triviális kijelentés, hiszen az esszét jellemzően nem tekintik többnek, mint a Kommunista Internacionálé pártszervezeti téziseihez fűzött kommentárnak. Előbb megvilágítom azokat az egymástól távol eső tradíciókat (egyfelől a lenini pártelméletet, másfelől az intézményesült szabadság hegeli koncepcióját), amelyekből Lukács építkezik, majd megmutatom, hogy e hagyományelemeket miképpen alakítja tovább a filozófus, és hogyan illeszti egymásba őket. Végül tisztázom e konstrukciónak a lukácsi rendszergondolkodásban betöltött funkcióját, és megrajzolom a kései munkásság felé vezető irányvonalakat is: rámutatok, hogyan lép az Ontológiában egyfajta „munkametafizika” a „pártmetafizika” helyébe.
PENERAPAN MODEL MAKE A MATCH PADA PEMBELAJARAN IPS SISWA KELAS IV SD NEGERI LUBUK KEMANG
Authors: Fitriani Fitriani , Satria Tio Gusti , Valen Andri
Published: September 2023

ABSTRAK

Penelitian ini bertujuan untuk: Apakah hasil belajar siswakelas IV SD Negeri Lubuk Kemang setelah penerapan model Make A Match secara signifikan.Desain eksperimen yang digunakan berbentuk control group pre-test-pos-test. Control group pre-test-pos-test yaitu pre-test dan post-test diberikan pada kelas eksperimen..Populasi dalam penelitian ini adalah seluruh siswa kelas IV SD Negeri Lubuk Kemang dengan sampel berjumlah 25 siswa. Teknik pengumpulan data yang digunakan adalah tes, Teknik analisis menggunakan uji z. Hasilpenelitian disimpulkan bahwa model pembelajaran Make A Match dapat meningkatkan hasil belajar siswa  Kelas IV SD Negeri Lubuk Kemang dalam pembelajaran IPS. Setelah diterapkan model pembelajaran Make A Match  siswa lebih tertarik dan berminat dalam pembelajaran IPS. Hal ini terlihat dari peningkatan hasil belajar yang dilakukan melalui kegiatan tes. Pada pretes nilai rata-rata ketuntasan siswa sebesar 41,69 dinyatakan belum tuntas sedangkan pada postes nilai rata-rata ketuntasan siswa  sebesar 70,31 dan dinyatakan tuntas..

 

Kata Kunci:Penerapan Model Make A Match, Ilmu Pengetahuan Sosial, Sekolah Dasar
PENERAPAN MODEL PEMBELAJARAN PROBLEM BASED LEARNING UNTUK MENINGKATKAN HASIL BELAJAR MATEMATIKA SISWA
Authors: Sinaga D. Yuliana , Sidabutar Ropinus
Published: September 2023

This study aims to improve students' mathematics learning outcomes with the Learning Based Learning Model in the 2013 T.A 2021/2022 Curriculum. This research is a classroom action research conducted in two cycles. Each cycle consists of 4 stages, namely: planning, implementation, observation, and reflection. The subjects of this study were fourth grade students, totaling 35 people consisting of 15 males and 20 females. The object of research is the result of students' mathematics learning. Data were analyzed using descriptive statistics. The results showed that the Problem Based Learning learning model can improve the mathematics learning outcomes of fourth grade students in the 2013 Curriculum. This is known from the pre-cycle student learning outcomes with an average score of 60.50 and learning completeness of 42.85% in the low category. In the first cycle, the results experienced an average value of 68.85 and 51.42% learning completeness which was in the sufficient category. The research was continued in the second cycle and obtained an average score of 80.35 and a learning completeness of 82.85% which was in the high category and had met the criteria for indicators of research success. So, it can be concluded that the application of the Problem Based Learning learning model can improve students' mathematics learning outcomes.
Supervised exercise therapy apps for claudication
Authors: Chan E , Pathmanathan S , Sultan K
Published: September 2023

Peripheral arterial disease (PAD) has been recognised as a healthcare burden affecting up to 5.56% of the global population over 25 years of age.1 Intermittent claudication (IC) is often debilitating and results in reduced physical activity which is associated with increased cardiovascular disease and all-cause mortality.2,3 Early identification and management of PAD is essential to improve symptoms and prevent a downward trajectory towards limb loss. Supervised exercise therapy (SET) is the widely recommended first- line treatment for IC. Despite the benefits of SET, uptake and adherence rates are recognised to be poor.4 The reasons for poor SET compliance are multifactorial and include time constraints, travelling distance, personal, financial and institutional barriers.5 To overcome these barriers, alternative methods for delivering SET need to be explored.
Validity and reliability of innovative behaviors of nurses and midwives scale: A scale development study
Authors: Can eyda , Dalcal Berna , Durgun Hanife
Published: September 2023

Aim: This research was carried out to develop a measurement instrument to determine the innovative behaviors of nurses and midwives.
Materials and Methods: This study, which is of a methodological nature was applied with 216 nurses and midwives between 01.06.2021-31.09.2021. The item pool of the scale was created by the researchers with the literature as twenty-three items in a five-point Likert type and submitted to the opinions of twelve specialists.
Results: The three-factor scale structure designed by making explanatory and confirmatory factor analysis was confirmed with the validity and reliability. According to the analysis results; the scale consisted of three sub-dimensions (managerial and personal; physical and occupational; organizational and environmental) and 15 items. It was founded that the content validity index of the scale items was 0.468-0.851; factor loads were 0.510-0.871; item-total score correlations were 0.467-0.768, and the Cronbach's alpha reliability coefficient of the sub-dimensions ranged between 0.703-0.876 and it was 0.912 for the whole scale.
Conclusion: As a result of the validity and reliability analyzes of the Attitude Scale towards Innovative Behaviors of Nurses and Midwives, it was founded that it can be used as a valid and reliable scale.
Investigation of vitamin D, vitamin B12 and ferritin levels in children receiving Home Health Care Services in Southeastern Turkey
Authors: Orhan Ozhan , Solmaz Murat
Published: September 2023

Objective: For proper nutrition of children followed by the Home Health Care (HHC) unit, a close follow-up is extremely important. Vitamin deficiencies are common in children in this group who need parental or caregiver-dependent nutrition. The purpose of this study conducted in Batman Province, was to investigate vitamin D, vitamin B12 and ferritin levels of individuals under 18 years of age who are followed by the HHC unit and continue their lives and treatments at home, except for emergencies.
Materials and Methods: This study was derived from the files of 416 pediatric patients who were followed up in Batman Province HHC unit between January 1, 2022, and December 31, 2022. It was designed as a retrospective, single-center study evaluating 25-hydroxyvitamin D (OH) levels, vitamin B12 levels, ferritin levels, and demographic variables from individuals followed by HHC unit. The data were collected from the HHC unit’s files. IBM-SPSS version 24 was used for analysis.
Results: The mean age of the 416 children receiving home health care services included in the study was 10.38±4.37 years. 234 (56.2%) of the participants were male and 182 (43.8%) were female. The 25(OH)D level was 18.47±5.41 ng/mL for all ages, and the ferritin level was 34.90 (33.08) ng/mL. The vitamin B12 level was 480.31±190.38 ng/L. The 25-OH-D vitamin levels of the children in the study was significantly low.
Conclusion: Patients followed within the scope of home health care services are at risk for malnutrition and vitamin deficiencies, and annual follow-up of the patients in this regard and personalized diet programs should be created. Vitamin D insufficiency and deficiency are common in children in this group, who cannot leave the house except for compulsory situations and cannot benefit from sunlight sufficiently. We think that these children with chronic diseases should take vitamin D prophylaxis.
DETERMINATION OF THE OPTIMUM PLATELET-RICH PLASMA METHOD FOR THE ESSENTIAL AMOUNT OF PLATELETS
Authors: KIRIMLIOGLU ESMA , YAPICI AHMET
Published: September 2023

Objective: Platelet-rich plasma (PRP) is the cellular plasma component containing a higher platelet concentration obtained by centrifugation of autologous peripheral blood. PRP has an auxiliary role in regenerative medicine treatment. Current treatment protocols for tissue repair strategies may be globally insufficient. PRP treatment via Platelet-released growth factors (GF) supports inflammation, proliferation, and wound healing. PRP studies have progressed and have proposed different formulations in recent years. Although various methods and devices are used, there are few and different standardized protocols to obtain PRP with the highest platelet concentration. Although anticoagulants containing citrate are primarily preferred in PRP production To provide effective platelet concentration in PRP, we noticed differences in the literature regarding PRP tube volumes, anticoagulant-citrate, and blood amounts. We aimed to obtain the most appropriate platelet concentration in PRP treatment by using different concentration ratios of Acid Citrate dextrose (ACD) solution A and different blood amounts and introducing a new treatment method to the literature. Methods: The blood of 30 individuals aged between 30 and 75 was taken into 10cc laboratory tubes, and 15cc and 18cc hourglass-shaped PRP tubes containing 8% ACD-solution A. Blood fractions were separated by centrifugation, buffy coat area was collected, and count platelet amount by Hematology Analyzer. Results: The platelet amount per µl was statistically significantly higher in 18cc blood compared to 15cc and 10cc. Platelet amounts obtained from 15 and 18cc peripheral blood with 8% ACD-solution A were above the effective treatment amount recommended in the literature. Conclusion: It was observed that the amount of used blood volume was correlated with the amount of obtained platelets.
Serum Uric Acid to HDL-Cholesterol Ratio Could Be Promising Predictor of Atrioventricular Nodal Reentrant Tachycardia
Authors: nmez ibrahim , gun Mehmet , Bayraktar Muhammed , Korkmaz Ufuk , Demirel Mustafa , Acar Emrah , ne Y
Published: September 2023

Objective: Paroxysmal supraventricular tachycardia (PSVT), particularly atrioventricular nodal reentrant tachycardia (AVNRT), is a common arrhythmia with no associated structural heart disease. Inflammation has been implicated in the pathogenesis of arrhythmias. Uric acid to HDL-cholesterol ratio (UHR) is a novel inflammation marker that has been investigated in various conditions. This study aimed to explore the potential association between UHR and AVNRT.
Material and Methods: A total of 136 patients were included in the study, including 86 patients with AVNRT and 50 controls with normal electrophysiologic study. All patients' medical records were reviewed, and data were obtained retrospectively. We recorded baseline features, hematologic and biochemical markers, and determined the UHR value.
Results: UHR (p=0.031) and uric acid (p<0.001) levels were significantly higher, while HDL cholesterol (p=0.031) levels were significantly lower in the AVNRT group. Neutrophil leukocyte ratio (NLR) was also higher in the AVNRT group (p=0.034). However, in multivariate analysis, only UHR emerged as an independent predictor for AVNRT (OR: 1.088; 95%CI: 1.022 – 1.159; p=0.008). ROC curve analysis suggested a UHR cut-off > 14.05 for predicting AVNRT with 56% sensitivity and 76% specificity.
Conclusion: This study identifies UHR as a promising predictor for AVNRT, shedding light on the potential role of inflammation in the arrhythmia's development. Utilizing UHR as a readily accessible marker in the evaluation of AVNRT patients may have clinical implications.
Bibliometric analysis of primary central nervous system lymphoma
Authors: GUVEN Serkan , ALKAN Sevil
Published: September 2023

Aim: Primary central nervous system lymphoma (PCNSL) is an important topic in hematology due to its rare, aggressive course, difficult diagnosis and special treatment requirements. This bibliometric analysis study aimed to examine PCNSL -related publications published since the last 2000 and to identify potential points of future research.
Material and methods: Web of Science Core Collection documents published between 2000 and 2022 were analyzed using selected keywords. The obtained data were visualized with bibliometric tools. Publishing countries, organizations, journals, authors, references, and keywords were all examined comprehensively.
Results: 1,160 articles on PCNSL published since 2000 were retrieved. These publications tend to focus on research in oncology (n=456, 39.310%), clinical neurology (n=354, 30.517%), and hematology (n=173, 14.914%). Search criteria revealed that 6,458 authors from 65 different countries and 1,570 organizations worldwide contributed to PCNSL articles.
Conclusion: Studying research on PCNSL is crucial to improve our knowledge of this disease and to create new treatment strategies. It is very important to keep in mind that the characteristics and trends in PCNSL research may change over time as new findings and developments in the field are discovered.
Evaluation of Clinical Findings in Patients with Lichen Planus: A retrospective study
Authors: esen mustafa
Published: September 2023

Aim: Lichen planus is a papulosquamous disease that affects skin and mucous membranes. In this study, we aimed to evaluate the clinical and demographic characteristics, treatment models, and accompanying comorbidities of patients with lichen planus.
Materials and methods: Our study included 202 patients who were diagnosed with LP clinically and histopathologically between May 2018 and May 2023. Patients' age, gender, involvement features, additional systemic diseases, laboratory findings and applied treatments were recorded retrospectively.
Findings: Of the 202 patients in our study, 116 (%57.4) were female and 86 (%42.6) were male. The average age of the patients was 46.42 years (13-84). The average duration of the disease was 10.40 months (1-196). The classic type (120 patients, %64.9) was observed most typically in skin involvement, while reticular pattern (60 patients, %85.7) was observed in oral involvement. Skin involvement was detected in 185 (%91.6), oral mucosa involvement in 70 (%34.7), genital involvement in 16 (%7.9), scalp involvement in 30 (%14.8), inverse involvement in 20 (%9.9), palmoplantar involvement in 5 (%2.5) and nail involvement in 21 (%10.4) of the patients, while no ocular involvement was detected. Anti-HCV positivity was found in two (%1) patients. HBsAg positivity was detected in 11 (%5.4) patients. While the most frequent accompanying comorbidity was hypertension with %20.3 (n:41), depression-anxiety was the sequent with %14.4 (n:29). While 154 (%76.2) of the patients received only topical treatment, it was seen that 5 (%2.5) patients were given only systemic treatment. In comparison of the age groups 18-45 and >45, the ratio of DM, hyperlipidemia and hypertension was identified significantly high in the group >45.
Conclusion: Our study shows many similarities with the literature data. However, we believe that prospective cohort studies including more patients are needed to understand LP, whose clinical and epidemiology has not been sufficiently elucidated.
The Investigation of the Relationship Between Blood Parameters, Sleep Quality, and Quality of Life of Patients Using Depot Antipsychotics
Authors: l N
Published: September 2023

Aim: In our study, we aimed to examine the relationship between laboratory tests with sleep and quality of life in patients using depot antipsychotics as monotherapy for the last three months.
Materials and Methods: Patients with schizophrenia and receiving monotherapy depot antipsychotic form were included in our study. Calgary Depression in Schizophrenia Scale (CSS), Positive and Negative Syndrome Scale (PANSS), Pitssburg Sleep Quality Index (PUKI), Scale of Short Form-36 (SF-36) were administered. The laboratory parameters of the participants were evaluated.
Results: Sixty one to study; 80.3% male and 19.7% female patients were included. The mean age of all patients was 36.40±9.96, and the mean body mass index was 24.49±5.18. There was no significant difference between the groups in terms of PSQI subscales and total scores (p>0.05). Only the social functioning score for SF-36 was worse than the other two groups of patients using zuclopenthixol depot (p=0.049). There was no difference between the groups in SF-36 other subscale scores (p<0.05). Prolactin value and other laboratory parameters were also not different between groups (p>0.05).
Conclusion: Based on the results we have obtained, general functionality levels such as sleep and quality of life of the patients should be considered while determining the depot antipsychotic forms. In order to generalize and interpret the findings of our study, there is a need to conduct studies involving larger sample groups and different periods of the disease.
Comparison of the Efficacy of Epidural Blood Patch and Transnasal Sphenopalatine Ganglion Block in the Treatment of Postspinal Puncture Headache
Authors: Canakci Ebru , Coskun Ilker
Published: September 2023

Aim: Postspinal puncture headache (PDPH) affects postoperative recovery and patients' quality of life after surgery. PDPH is the most common complication of spinal anaesthesia that affects patients' well-being the most. The epidural blood patch (EBP) is the gold standard for interventional treatment of PDPH. Sphenopalatine ganglion block (SPGB), a new noninvasive method for treating PDPH, has come to the forefront. SPGB is noninvasive and very easy to perform compared with EBP. This study aims to compare the efficacy of the two interventional methods in treating PDPH.
Material and Method: Between January 1, 2018, and February 1, 2023, 30 cases diagnosed with PDPH underwent EBP and 28 SPGB. Case demographics, type of surgery performed, whether complications occurred after the procedure, and the amount of acetaminophen taken within 24 hours were recorded in mg. The VAS scores were recorded 8 times, in the first half hour before and after surgery, and, 1, 2, 4, 6, 12 and 24 hours after the surgery.
Results: There was no statistically significant difference between the distributions of sex, type of surgery, and amount of acetaminophen taken after surgery by groups (p values respectively p= 0.245, p=0.994, p=0.131 ). There was a statistically significant difference between the distributions of 4th-hour values VAS by group (p=0.008). There is a statistically significant difference between the groups' distributions of the values of the 6th-hour VAS (p=0.016). VAS scores were lower in the epidural blood patch group. There was no difference between the VAS scores in the blood patch and block group in all other measurement periods. Nevertheless, comparing the time variables of the groups, the main effect of time has a statistically significant impact on the VAS (p < 0.001). There was a significant difference in the sphenopalatine ganglion block and epidural blood patch groups when the pre-surgery VAS value was compared with all post-surgery periods (p < 0.001, p < 0.001).
Conclusion: The epidural blood patch is the gold standard in treating postspinal headaches. However, it is a difficult procedure to perform since it is an invasive procedure. Sphenopalatine ganglion blockade is a treatment modality with very close efficacy to epidural blood patches in treating postspinal headaches. It can be used as an alternative treatment method in cases that do not accept treatment with the epidural blood patch. As postspinal headache mostly occurs in obstetrics patients, it can be safely used to protect a newborn mother and the baby from the side effects of drugs that pass into the breast milk.
A Prediction Model Created by Comparing Tree-Based Methods To Assess Coronary Artery Disease
Authors: an zekeriya , ek ipek
Published: September 2023

Aim: As people's quality of life and habits have changed, Coronary Artery Disease (CAD) has become the leading cause of death globally. It is a complicated cardiac disease with various risk factors and a wide range of symptoms. An early and accurate diagnosis of CAD allows for the quick administration of appropriate treatment, which contributes to a decreased mortality rate. Machine learning (ML) algorithms for CAD prediction and treatment decisions are quickly being developed and implemented in clinical practice. Predictive models based on machine learning algorithms may aid health personnel in the early diagnosis of CAD, lowering mortality. Thus, this study goal is to forecast the elements that may be connected with CAD using tree-based approaches, which are one of the machine learning methods, and to discover which factor is more effective on CAD.
Material and Methods: The open-access heart disease dataset was used within the scope of the study to investigate the risk factors related with CAD. The data set used contains the values of 333 patients, as well as 20 input and 1 target variables. The 10-fold cross validation approach was employed in the modeling, and the data set was divided as 80%: 20% as training and test datasets. For model assessment, the measures of accuracy (ACC), balanced accuracy (b-ACC), sensitivity (SE), specificity (SP), positive predictive value (ppv), negative predictive value (npv), and F1-score were utilized.
Results: The values of ACC, b-ACC, SE, SP, ppv, npv, and F1-score performance metrics were 9 98.5%, 98.8%, 97.7%, 100%, 100%, 95.8% and 98.8%, respectively, as a consequence of the estimate model results created with the XGBoost approach, which has the best performance among tree-based models. When the groups with or without CAD were compared, a statistically significant difference was found in terms of the age variable. There is also a significant relationship between the active, lifestyle, ihd, dm, ecgpatt, qwave variables and the presence/absence of the CAD variable. When the variable significance values obtained as a result of modeling with the highest performing XGBoost are examined, it is seen that the variables that most associated with CAD are ekgpatt: normal, ekgpatt: ST-depression, ekgpatt: T-inversion, qwave: yes, age, bpdias, height, LDL, HR, IVSD: with LVH, bpsyDM.
Conclusion: According to the performance criteria of the forecasting models used, CAD gave distinctively successful results in forecasting. By identifying risk factors associated with CAD, the proposed machine learning models can provide clinicians with practical, cost-effective and beneficial assistance in making accurate predictive decisions.
Migraine chronification is associated with higher body mass index and elevated serum interleukin-6 levels
Authors: VURALLI Doga , BOLAY Hayrunnisa
Published: September 2023

Background/Aim: Chronification of migraine is a serious health problem with difficulties in management and related to increased disability. Inflammation is suggested to have a role in migraine and its chronification. We aimed to determine whether systemic inflammatory response tested by serum interleukin-6 (IL-6) levels and obesity were related to migraine attack frequency.
Methods: A total of 40 female participants (20 chronic migraine, 10 episodic migraine, 10 healthy controls without headache) were included in the study. None of the migraine patients were on migraine prophylaxis. Episodic migraine patients were evaluated interictally with a 72 hour headache free period before and after blood collection. Migraine headache frequency, body mass index (BMI) and age of the patients were recorded. Serum IL-6 levels were measured by ELISA method.
Results: Serum IL-6 levels were significantly elevated in chronic migraine patients compared to episodic migraine patients and healthy controls. BMI was higher in chronic migraine patients compared to episodic migraine patients and healthy subjects even though it did not reach statistical significance. Serum IL-6 levels and BMI were positively correlated with migraine headache frequency.
Conclusion: Elevated systemic circulating IL-6 levels and BMI were related to an increase in migraine headache frequency. BMI and serum IL-6 levels seem to be risk factors for chronic migraine in women. Strategies to reduce inflammation and obesity must be integrated to the treatment of chronic migraine. Identification of modifiable risk factors for chronification of migraine is crucial for sustainable treatment of migraine.
Comparison of RDW and PLR values with CRP and NLR values in patients with postoperative leakage and abscess after pancreatectomy
Authors: Umman Veysel , Gumus Tufan , Kivratma Hamza , Temel Recep , Uguz Alper , Zeytunlu Murat
Published: September 2023

AIM: New studies show red cell distribution width (RDW) to be altered by inflammatory cell wall changes in acute pancreatitis, sepsis and critical illness. We aimed to evaluate the efficacy of RDW, platelet lymphocyte ratio (PLR) and neutrophil lymphocyte ratio (NLR) values in patients who underwent pancreatectomy.

MATERIALS AND METHODS: Fifty patients who underwent pancreatectomy were retrospectively compared. The study group consisted of patients who were followed up with clinical or laboratory evidence of either leakage or infection, with proof of infection being culture positivity and associated fever, tachycardia, and elevated laboratory values. The control group, on the other hand, comprised of 25 patients with uneventful postoperative course. RDW, neutrophil, platelet (PLT), aspartate aminotransferase (AST), alanine transaminase (ALT), C reactive protein (CRP), PLR and NLR values of the patients were compared among and between groups at 4 different time points (1: admission, 2: postoperative first week prior to infection, 3: at the time of infection and 4: discharge).

RESULTS: Statistically significant results were obtained for ALT, CRP, neutrophil, and PLR ratios (p=0.003, p=0.002, p=0.028, p=0.032, respectively). Significant differences were also observed in RDW 2, RDW 3 and RDW 4 (p=0.034, p=0.010, p=0.031, respectively). Regarding CRP levels, significant differences were found for CRP 1 and CRP 3 levels (p=0.001, p=0.025, respectively). A significant difference was detected only for the PLR 4 value (p=0.009).

CONCLUSIONS: In patients who underwent pancreatic resection and were suspected of having infection that progressed to a septic state, the levels of RDW, CRP, PLT, and PLR were observed to be correlated with infection and increased at various intervals before the culture results and evidence of infection emerged. Due to their association with the emergence of infections, these parameters have been proven to be effective and affordable tools in clinical decision-making.
The Relationship with Disease Severity of Ischemia-Modified Albumin Levels in Diabetic Nephropathy
Authors: ENER G , kun Cihan , lu Esra , Can Ba , Evran Bet
Published: September 2023

Background: While type 2 diabetes (T2DM) is increasing rapidly, developing diabetic complications are the leading cause of morbidity and mortality. Biochemical markers are important for early diagnosis and treatment of nephropathy, which is a common complication. The aim of this study is to evaluate serum ischemia-modified albumin (IMA) levels in the development of diabetic nephropathy in T2DM patients and to determine the effectiveness of this parameter in predicting the presence and severity of nephropathy.
Materials and Methods: 68 adult patients diagnosed with T2DM and 30 healthy controls were included in this study. The T2DM group consisted of 34 patients without microalbuminuria (<30 mg/g) and 34 patients with microalbuminuria (30–300 mg/g) according to albumin/creatinine ratio (UACR). Biochemical data and serum IMA levels of the patient and control groups were measured and compared.
Results: In terms of IMA levels, the difference between T2DM patients with microalbuminuria (0.55 ± 0.08 ABSU) and without microalbuminuria (0.42 ± 0.05 ABSU) and control (0.37 ± 0.08 ABSU) groups was significant (p<0.0001). The T2DM group with microalbuminuria had the highest glucose, HbA1c, UACR, and IMA levels. There was a positive correlation between IMA levels and UACR (r = 0.541, p < 0.001). IMA had a weak correlation with HbA1c (r = 0.345, p = 0.002). ROC analysis was performed and the IMA test had a high diagnostic value in the diagnostic differentiation of T2DM patients with microalbuminuria. According to multiple logistic regression analysis, IMA levels were an independent risk factor for DN (p = 0.003).
Conclusions: Our data showed that IMA values increased significantly in diabetic patients, especially in those with microalbuminuria, and this increase was correlated with UACR levels. This study has shown that increased IMA levels are an important marker for the presence and severity of microalbuminuria in diabetic patients and therefore may be important in the early detection of renal dysfunction in T2DM. We even think that it can be used as an important marker in the follow-up of diabetic patients, even before the development of microalbuminuria.
Prosodic Analysis of Humor in Stand-up Comedy
Authors: Naz Asma , Farooq Dr. Muhammad Umar , Jabeen Sajda
Published: September 2023

The present study investigated the prosodic features employed by Trevor Noah to create humor in his stand-up comedy. The study used quantitative paradigms to frame the verbal narrative. The research employed, Prosodic Markers of Saliency in Humorous Narratives (Pickering et al., 2009) as theoretical framework for prosodic features. Firstly, the data was anatomized via systematic prosodic and cognitive incongruities between the jokes’ setup and the punch lines. Secondly, for each humorous narrative, a series of measurements including pitch, volume, and pause, as identified by Praat (6.1), were used as a framework to dig out the implicit and explicit factors that caused humor in stand-up acts. The data analysis showed that the orator employed a substantial pause before delivering his punch lines which created humor. The study concluded that prosody played a vital role in creating humor, which falls within the domain of linguistics. The study was significant as it contributed to research concerning narrative forms of jokes based on instrumental prosodic analysis. Further, the research might be conducted to analyze other paralinguistic markers of humor, such as the use of laughter and smile during the delivery of jokes in different Pakistani sitcoms and stand-up comedy, to enlarge the studies on humor’s scope.
Diagnostic utility of the systemic immune-inflammatory index in preterm neonates with late-onset sepsis
Authors: VARDAR Gonca , ÖZEK Eren
Published: September 2023

Objective: To assess if systemic immune-inflammatory index (SII) has a diagnostic role for late-onset sepsis (LOS) in premature

neonates.

Patients and Methods: A single-center retrospective observational study including preterm infants with culture-proven LOS and

controls was conducted between January 2017 and December 2022. SII was derived using complete blood count values acquired at the

beginning of and three to five days before LOS. SII was compared between the LOS group and controls.

Results: A total of 144 infants were included in the study. The SII values of the LOS group were found to be significantly increased in

comparison to the control group [376.74 (11.11 – 15170) vs. 235.24 (46.83 – 1214.38) (median, min-max), P =0.018]. The SII values

significantly increased when pre-sepsis and LOS values were compared [200.6 (0 – 1295.78) vs. 328.28 (0 – 14678, P
Innovative distal bolt-locking screw tibial nailing method and conventional nailing: A comparison of outcomes
Authors: KART Hayati , DEMIRTAS Abdullah , UYGUR Mehmet Esat , AKPINAR Fuat
Published: September 2023

Objectives: Distal bolt-locking screw (DSBLS) tibial nailing offers an innovative method in which the nail is locked upon entering the

screw. The current study compares the clinical, radiological, and functional outcomes of DSBLS tibial nails with conventional tibial

nails.

Patients and Methods: We retrospectively evaluated 38 tibial fractures of 37 patients treated with intramedullary nailing. In Group

1, 21 fractures were treated with DSBLS nailing, while in Group 2, 17 fractures were treated with conventional nailing. Duration of

surgery, time to weight-bearing, time to union, presence of deformity, return to work and sports, complications, American Orthopedic

Foot and Ankle Society Score (AOFAS) and Olerud-Molander Ankle Score (OMAS) values were compared between the groups.

Results: Group 1 patients had significantly shorter time to full weight-bearing than patients in Group 2 (P=0.032). There was no

significant difference between the groups in functional comparisons according to the AOFAS. In contrast, the outcomes of Group 2

were better than those of Group 1 according to the OMAS (P=0.475 and P=0.037). The outcomes for the other variables were similar.

Conclusion: In this method, patients can bear weight in a shorter time. The results of DSBLS nailing are as good as conventional nails,

and it can be safely preferred in treating tibial fractures with intramedullary nailing.
Building Footprint Extraction from LiDAR Data Using SVM Classification
Authors: JOURNAL IJSREM
Published: September 2023

Automatic detection of buildings from very high resolution (VHR) satellite images is a current research hotspot in remote sensing. In this work presents a novel approach to detect the buildings by atomization of the training area collecting stage for supervised classification. The classification method for the analysis of satellite image based on Normalized Difference Vegetation Index (NDVI). The method employs the multi-spectral remote sensing data technique to find spectral signature of different objects such as vegetation index, land cover classification, concrete structure, road structure, rural and urban areas, rocky areas and remaining areas presented in the image. In the experiments, the proposed SVM framework outperformed for the three (Linear SVM, Cubic SVM, Medium Gaussian SVM) methods tested. SVM is trained through supervised learning to classify each location in the image as “buildings” or “Non-buildings.” Finally, SVM algorithm to find the accuracy value, training time and receiver operating characteristic curves to evaluate detection performance, and compare the proposed algorithm with several existing methods.
An Empirical Study of Inventory Management with reference to Construction Sector
Authors: Mukherjee Chanchal , Rao Dr. P. Venkata
Published: September 2023

Inventory management is a critical part of construction Industry. Inventory Management system consist of different tasks like finding suitable materials, procurement process of those materials, transportation. Inventories represent the second largest asset category for construction companies, next to plant and equipment. Inventory would be the number of raw materials, fuel and lubricants, spare parts and semi- processed material to be checked inventories for the smooth running of construction firm. The main objective of our study is to investigate the efficiency and its impact in application of inventory management system in construction projects. Identification of impacts and risk influence of inventory management systems in a construction project. The lack of proper handling and storage of material in construction site has made it difficult to track and locate the material availability and suggestion about inventory management system and its control over efficiency construction projects will be analyzed and the outcome of the effective utilization of inventory at construction site to overcome the difficulties by giving best the possible recommendations. ABC analysis is one of the most conventionally inventory management system suited for construction infrastructure. Keywords: Construction, Efficiency, Inventory, Management, Material, Organizations, Productivity
Practical Recommendations on Micronutrient Deficiencies in Gastrointestinal Diseases
Authors:   Gujarat Gastro and Vascular Hospital, Surat, Gujarat, India, Shah Bidita , Shah Saumin
Published: September 2023

Almost all the micronutrients being absorbed in gastrointestinal tract, patients with gastrointestinal disorders are at highest risk of having multiple nutritional deficiencies including micronutrient deficiencies. Malnutrition and deficiencies can be prevented or treated by optimal medical nutrition therapy, yet limited specific knowledge about micronutrients remains among clinicians. Further knowledge on trace elements remains miniscule as compared to vitamins. Practical recommendations based on available micronutrient guidelines are therefore required regarding procedures for determination of requirements and, especially for gastrointestinal diseases as this is the commonest encountered problem that can impair enzymatic as well as biochemical processes and lead to multiple complications including death. Here we have tried to give consensus based recommendations to help practicing dieticians and clinicians making decision regarding specific micronutrient deficiencies and their implications in gastrointestinal diseases. Keywords: Practical recommendations on micronutrient deficiencies in gastrointestinal diseases, Malnutrition, IAPEN INDIA consensus statement
Cost-Effective Evaluation of Homemade Recipes in Cancer Patients on Liquid Diet from Low-Middle-Income Group Countries
Authors:   Departments of Radiation Oncology, Kasturba Hospital, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha , Maharashtra, India, Kalbande Pallavi , Kale Pournima , Rangari Payal , Datta Niloy R
Published: September 2023

Cancer patients, on liquid diet are at a high-risk of malnutrition. 10-20% of patients are estimated to die due to malnutrition rather than malignancy itself. In low-middle-income group countries (LMICs), patients are mostly undernourished. They need cost-effective, easily available and acceptable nutritional support. The study has been undertaken to evaluate the cost-effectivity of homemade recipes vs commercially available nutritional formulations for patients on liquid diet. Recipes for both vegetarian and nonvegetarian were designed using low-cost and locally available ingredients to fulfil the daily calorie requirement of ≈2,000 kcal (30 kcal/kg for a 65 kg adult) with ≥90 gm of protein (1.5 gm/kg). Alongside, five commercial nutritional formulations were evaluated to meet the above requirements. The caloric (380 ± 80.1 kcal/100 gm, 260–474 kcal) and protein contents (32.6 ± 10.9/100 gm, 15–49 gm) in commercial supplements were variable. For providing 2,000 kcal with minimum of 90 gm protein, the cost of commercial formulations ranged from INR 745 -3,461/day (1,700 ± 946). Comparatively, the vegetarian and non-vegetarian homemade recipes were estimated to cost just INR 135/day and INR 182/day respectively. For the 2000 kcal diet, the difference in nutrient contents of commercial vs homemade preparations were non-significant, while the cost was significantly lower with homemade recipes (p=0.03). Homemade recipes designed and suited to individual needs could meet the dietary requirements for patients on liquid diet, be highly cost-effective and thereby especially suit patients from resource constraint settings, like LMICs. Keywords: Nutrition, Cancer, Liquid diet, Malnutrition, Low middle­income countries, Nutrition supplement
ANALYSIS OF THE IMPACT OF FINANCIAL BALANCE INDICATORS ON THE STOCK MARKET PERFORMANCE OF COMPANIES LISTED ON THE BUCHAREST STOCK EXCHANGE
Authors:   University of Craiova, Craiova, Romania, Dumitrescu Ioan-Alexandru , Dorobanțu Alin-Ionuț ,   University of Craiova, Craiova, Romania
Published: September 2023

"This paper deals with the topic of the impact brought by the factors that contribute to the determination of financial balance indicators on the profitability of Romanian companies listed on the Bucharest Stock Exchange during several consecutive financial years. The subject under research was the subject of several studies that make up the specialized literature. The purpose of the research is to analyse the existence and intensity of the link between the financial balance indicators, determined semi-annually, and the economic performance of the companies, expressed through the profitability indicators. The research method used in the elaboration of the present study is that of multiple regression analysis of the data, applied using the SPSS statistical program."
THE CONTRIBUTION OF THE EU FDIs TO THE REDUCTION OF ROMANIA'S MANUFACTURING PRODUCTION CO2 EMISSIONS: HIGHER EXPORTS AND GDP GROWTH
Authors:   Bucharest University of Economic Studies, Bucharest, Romania, Epurescu Vlad
Published: September 2023

Reducing the CO2 footprint of Romanian manufacturing production under the positive influence of the EU foreign direct investments (FDIs) can have a substantial contribution to Romania’s presence on the EU common market. Moreover, it might contribute to the increase the country’s GDP. To prove the assumptions, the author developed an econometric model that he called „A predictive model of the CO2 emissions inter-country interaction”, based on multiple linear regression, using a highly unique and latest database published by Eurostat, in 2022. He also designed several scenarios regarding the positive impact on the Romanian economy based on reducing the CO2 emissions generated by the EU FDIs. In the base scenario, a 1.5% annual reduction of the CO2 emissions generated in Romania due to the FDIs originating from the EU Member States could stimulate an 1% annual increase of the intra-community deliveries. This impact would determine an increase of Romania’s GDP by 0.3%. To have a realistic contribution to achieving the goal of a net zero economic model, the EU FDIs should obtain, between 2025 – 2050, a ten-time decreasing rhythm of their CO2 emissions. From minus 0.4%, the actual average decrease annual level between 2010 – 2020, the FDIs must decrease their emissions by 4% per year. This would increase Romania’s annual intra-deliveries by 2.6%, adding 0.8% per year to Romania’s GDP growth.