bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficacy of a transdiagnostic ecological momentary intervention for improving self-esteem (SELFIE) in youth exposed to childhood adversity: study protocol for a multi-centre randomized controlled trial
Authors: Daemen Maud , Postma Mary Rose , Lindauer Ramon , van der Meulen Iris Hoes - , Nieman Dorien , Breedvelt Josefien , van der Gaag Mark , Viechtbauer Wolfgang , Schruers Koen R. J. , van den Berg David , Bockting Claudi , van Amelsvoort Therese , Reininghaus Ulrich
Published: October 2020

Background: Targeting low self-esteem in youth exposed to childhood adversity is a promising strategy for preventing adult mental disorder, but psychological help remains difficult to access and accept for youth, calling for novel, youth-friendly approaches. Mobile Health (mHealth) and, most prominently, ecological momentary interventions (EMIs) provide a unique opportunity to deliver youth-friendly, personalized, real-time, guided self-help interventions. The aim of this study is to investigate the efficacy of a novel, accessible, transdiagnostic ecological momentary intervention for improving self-esteem (‘SELFIE’) in youth with prior exposure to childhood adversity.Methods/design: In a parallel-group, assessor-blind, multi-centre randomized controlled trial, individuals aged 12–26 years with prior exposure to childhood adversity and low self-esteem will be randomly allocated to SELFIE in addition to treatment as usual (TAU) as the experimental condition or the control condition of TAU only, which will include access to all standard health care. SELFIE is a digital guided self-help intervention administered through a smartphone-based App to allow for interactive, personalized, real-time and real-world transfer of intervention components in individuals’ daily lives, blended with three training sessions delivered by trained mental health professionals over a 6-week period. Outcomes will be assessed at baseline, post-intervention, and 6-month follow-up by blinded assessors. The primary outcome will be the level of self-esteem as measured with the Rosenberg Self-Esteem Scale (RSES).Discussion: The current study is the first to establish the efficacy of an EMI focusing on improving self-esteem in youth exposed to childhood adversity. If this trial provides evidence on the efficacy of SELFIE, it has significant potential to contribute to minimizing the deleterious impact of childhood adversity and, thereby, preventing the development of mental disorder later in life.
Investigating the broad domains of intrinsic capacity, functional ability and environment: An exploratory graph analysis approach for improving analytical methodologies for measuring healthy aging
Authors: Golino Hudson , Thiyagarajan Jotheeswaran Amuthavalli , Sadana Ritu , Teles Mariana , Christensen Alexander P. , Boker Steven M.
Published: October 2020

The current paper compared the empirical structure of 280 variables from the 2016 wave of the Health and Retirement Study (N = 16,327) estimated using exploratory graph analysis with a theoretical structure based on 20 broad domains of intrinsic capacity, functional ability and environment, identified in the International Classification of Functioning, Disability and Health compendium. The results showed that a structure with 21 first-order factors had the best fit to the data (i.e., lowest total entropy fit value) for both the training and validation sample. A second-order exploratory graph analysis was applied on the interfactor correlation matrix and identified five second-order factors. The five-factor structure presented a better fit than the theoretical three-factor structure (approximately) representing intrinsic capacity, functional ability and environment. A close inspection of the network structure generated by analyzing the rotated network loadings of the 21 first-order factors revealed an interplay between cognition, mobility, need for help with daily activities, walking capacity, physical capacity, liver functioning, positive affect and perceived mastery, low perceived control, and depression/negative mood. Combined, our results can help guide future research by providing a framework for estimating the structure of multi-domain aging research as well as generating questions that can be addressed in future research.
Development of a revised conceptual framework of physical training for measurement validation and other applications
Authors: Jeffries Annie , Marcora Samuele , Coutts Aaron J. , Wallace Lee , McCall Alan , Impellizzeri Franco Milko
Published: October 2020

A conceptual framework has a central role in the scientific process. Its purpose is to synthesize evidence, assist in understanding phenomena, inform future research and act as a reference operational guide in practical settings. We propose an updated conceptual framework intended to facilitate the validation and interpretation of physical training measures. This revised conceptual framework was constructed through a process of qualitative analysis involving a synthesis of the literature, analysis and integration with existing frameworks (Banister and PerPot models). We identified, expanded and integrated four concepts that are important in the conceptualization of the process and outcomes of physical training. These were: 1) formal introduction of a new measurable component ‘training effects’, a higher order construct resulting from the combined effect of four possible responses (acute and chronic, positive and negative); 2) explanation, clarification and examples of training effect measures such as functional (performance-based), physiological, subjective and other measures (cognitive, biomechanical, etc.); 3) integration of the sport performance outcome continuum (from performance improvements to overtraining); 4) extension and definition of the network of linkages (uni and bidirectional) between individual and contextual factors and other constructs. Additionally, we provided examples of theoretical and practical applications of the conceptual framework such as validation and conceptualization of constructs (e.g. performance readiness), and understanding of higher order constructs, such as training tolerance when monitoring training to adapt to individual responses and effects. This conceptual framework provides an overarching model that may help understand and guide the development, validation, implementation, and interpretation of measures used for athlete monitoring.
Implikatur Pada Berita Terjemahan (Kajian Prinsip Kerja Sama Maksim Grice pada BBCIndonesia.com)
Authors: Mustaqim Andika Hendra
Published: October 2020

Penelitian ini bertujuan untuk menganalisis implikatur pada berita terjemahan pada situs berita BBCIndonesia.com dengan membandingkan dengan situs berita aslinya BBC.com. Dengan menggunakan metode analisis teks, penelitian ini menggunakan pendekatan kualitatif dan berparadigma konstruktivis. Hasil penelitian menunjukkan implikatur memiliki peran yang sangat signifikan dalam proses penerjemahan. Pemahaman terhadap implikatur melalui prinsip kerja sama Grice menjadikan proses penerjemahan lebih memperhatikan keseimbangan makna antara bahasa sumber dan bahasa sasaran. Itu dikarenakan proses penerjemahan merupakan bentuk komunikasi antara penerjemah dengan pembacanya.
Nevsehir City Center Spatial Analysis of Noise Pollution by Using Geographical Information System
Authors: KALIPCI Erkan , BİLGEN İsmet , CÜCE Hüseyin
Published: October 2020

Nevsehir province in Turkey, which constitutes the study area, is a city located at the center of the Cappadocia region and has a history of about five thousand years. In this study, the precautions that might be taken in order to determine the level of noise pollution caused by traffic in main arterial roads of Nevsehir city center and to minimize negative effects of this experienced noise pollution on people were indicated. In total, the coordinates of 60 measurement stations were determined with the Magellan Explorist 710 Map handheld GPS receiver. Noise measurements were made with Svantek 971 brand Type 1 noise level meter. Noise pollution of the city center of Nevsehir was evaluated as positional through Geographical Information System (GIS) and maps showing noise pollution were prepared at morning, noon and evening hours. Since the results obtained from the measurements made in the main arteries are detrimental to human health, the precautions to be taken are briefly mentioned. The immediate implementation of identified measures can aid in reducing the level of noise pollution benefitting the Nevsehir city and the health of the people residing in it.
El valor especular del Coronavirus
Authors:   Universidad Autónoma de Chiapas, Durán Antonio
Published: October 2020

The coronavirus represents the mirror in which we can see reflect the State’s social reality. It strengthened the confinement we have been suffering due to poverty and violence. It revealed the need to improve our health system and dedicate a better social compromise to it. It warned us about our terrible eating habits. Finally, it made us commit to a less threatening lifestyle and also to a society linked to the natural world.
EL ORDEN INTERNACIONAL DESPUÉS DE LA PANDEMIA DEL COVID-19: ACELERACIÓN DE LA HISTORIA Y AGUDIZACIÓN DE LAS DESIGUALDADES
Authors:   Universidad Nacional Autónoma de México, Herrera Héctor
Published: October 2020

La irrupción de la pandemia de la COVID-19 provocará cambios en el orden internacional, sin embargo, contrario a quienes sostienen que dará origen a un escenario radicalmente distinto, lo que hemos visto es la aceleración de procesos que venían ocurriendo tiempo atrás como el declive de la hegemonía estadounidense, un mayor protagonismo de China, la emergencia de Estados más autoritarios, fracturas al interior de las organizaciones interna-cionales, pero también el surgimiento de ciertas iniciativas de cooperación, la agudización de las desigualdades producto de la pandemia y la crisis económica, así como un renovado estallido social que pone en cuestionamiento las exclusiones sistemáticas previas.
Порівняння ефективності різних фіксованих комбінацій антигіпертензивних препаратів у хворих з артеріальною гіпертензією та гіпотиреозом
Authors: Tseluyko V. I. , Korchagina D. A.
Published: October 2020

The aim – to assess the effects of different fixed double combinations of antihypertensive drugs and analyze their impact on heart remodeling in patients with arterial hypertension and hypothyroidismMaterials and methods. The study included 50 patients with hypertension and hypertension, which were divided into 2 groups by the method of blind envelopes of 25 people each. Patients in group 1 were assigned a fixed combination of perindopril with indapamide, patients in group 2 were assigned a fixed combination of perindopril with amlodipine. The groups were statistically compared by age, duration of hormonal substitution therapy, duration of hypertension, level of office SBP, DBP at inclusion in the study. In terms of body mass index, the study groups were comparable, but the number of obese patients was higher in group 2 (p=0.05). Observation of patients lasted 12 months.Results and discussion. The studied fixed combinations of antihypertensive drugs, namely perindopril with indapamide and perindopril with amlodipine provide a reduction in blood pressure in patients with hypertension with concomitant hypothyroidism according to the results of ambulatory blood pressure monitoring. Control of blood pressure in patients with arterial hypertension and concomitant hypothyroidism during a year of antihypertensive therapy provides a reduction in the severity of heart remodeling, the nature and extent of which depends on both the presence of obesity and the choice of a fixed combination of antihypertensive drugs.Conclusions. The results showed that in patients with AН and hypothyroidism achievement of euthyroid state contributes to BP reduction, but requires further administration of antihypertensive therapy. We studied fixed combinations of antihypertensive drugs, namely perindopril with indapamide and perindopril with amlodipine in patients with AG and associated hypothyroidism provide reliable blood pressure reduction according to the results of outpatient blood pressure monitoring (p<0.05). The fixed combination of perindopril with amlodipine compared with the fixed combination of perindopril with indapamide provides a significantly more significant effect on the regression of left ventricular myocardial hypertrophy, namely, a decrease in myocardial mass index by a degree of 2.7 in patients with obesity (р<0,01) myocardial mass index by body surface area in patients without obesity (p=0.06).
Комплексний інтервенційний підхід до діагностики і лікування пацієнта з ішемічною хворобою серця та синдромом підключично-хребтового обкрадання
Authors: Fedorchuk A. P. , Kucheriava M. V. , Mankovsky G. B. , Kuzmenko S. O. , Rudenko N. M.
Published: October 2020

The aim – to analyze of the complex treatment of a patient with coronary artery disease and subclavian-vertebral robbery syndrome, diagnostic methods of examination, observation and treatment.Materials and methods. The patient with coronary artery disease and occlusion of the left subclavian artery. Physical assessment methods were used? Such as: examination of the patient, anamnesis; laboratory and instrumental investigations – general blood analysis, biochemical blood analysis, electrocardiogram, echocardiography, coronary angiography of the carotid and subclavian arteries.Results and discussion. This complex interventional method of treating the patient had rather good angiographic result. The implantation of the stent system into the area of ​​critical lesion of the main left coronary artery and stent system in the occlusion of the left subclavian artery led to avoid the open surgical operation in the patient and to reduce the period of rehabilitation with a low postoperative risk.Conclusion. According to the international experience, in cases of planned phased treatment of coronary and peripheral arteries that require surgical intervention, it is better to give preference to the endovascular technique in patients with hemodynamically significant lesions. Percutaneous transluminal angioplasty and stenting should be the first therapeutic method for eliminating the problem of symptomatic lesions of the coronary and peripheral arteries.
Случай развития синдрома Дресслера у больного с острым диффузным миокардитом
Authors: Onyshchenko O. V. , Yepanchintseva O. A. , Riabenko D. V. , Todurov B. M.
Published: October 2020

A clinical case of the development of classic Dressler syndrome in a young patient with acute diffuse myocarditis is described. Timely diagnosis, administration of glucocorticoid and long-term complex therapy using beta-blockers (carvedilol), mineralocorticoid receptor blockers (eplerenone) not only led to the disappearance of Dressler’s syndrome, but also to a fairly rapid recovery of the patient from the underlying disease.
Діагностика міокардиту як одна з актуальних проблем кардіології
Authors: Kovalenko V. M. , Nesukay E. G. , Cherniuk S. V. , Polenova N. S. , Kirichenko R. M. , Giresh I. I. , Titov E. Yu. , Kozliuk A. S. , Botsiuk Yu. A.
Published: October 2020

Nowadays the diagnosis and prognosis of myocarditis is one of the most pressing, complex and incompletely solved problems in modern cardiology, that exist due to the large polymorphism of clinical manifestations of this disease and because of the lack of specific symptoms and diagnostic criteria. In most cases, the occurrence of heart failure, pain, heart rhythm and conduction disorders or other clinical manifestations are observed on the 2nd week after the onset of infectious disease, but inflammatory heart disease may not have a clear connection with the infection. Among the main methods used to diagnose myocarditis in clinical practice are electrocardiography (ECG), Holter monitoring (HM) ECG, echocardiography (echocardiography) and speckle-tracking (ST) echocardiography, cardiac magnetic resonance (CMR) imaging and endomyocardial biopsy. ECG and HMECG are highly informative methods for detection, prediction and dynamic monitoring of frequent complications of myocarditis – arrhythmias and conduction disorders. Two-dimensional echocardiography is a mandatory technique for assessing myocardial contractility that allows to assess the size of the heart chambers, systolic and diastolic function, global and regional contractility, the presence of thrombosis in the cavities, pericardial effusion and, most importantly. In recent years, there has been increasing data on the use of CT echocardiography for the diagnosis of myocarditis, based on the assessment of myocardial deformation and its rate in the longitudinal, radial and circular directions. Contrast-enhanced magnetic resonance imaging of the heart is non-invasive and one of the most informative methods for detecting signs of inflammatory myocardial damage. CMR allows to visualize the anatomy, study the structure and characterize the tissue of the heart, determine the functional features of the atria and ventricles. However, the gold standard for verifying the diagnosis of myocarditis to this day remains endomyocardial biopsy. Laboratory methods of diagnosis are additional researches, that in a complex with instrumental methods allow to estimate changes of myocardial inflammatory process at long supervision.
Pathogenetically-oriented therapy for novel coronavirus infection
Authors:   Bashkir State Medical University, Ufa, Russian Federation, Mukhamadieva L.R. , Mavzyutova G.A. ,   Bashkir State Medical University, Ufa, Russian Federation, Tyurina E.B. ,   City Clinical Hospital No. 5 of the city of Ufa, Ufa, Russian Federation, Kuzovkina O.Z. ,   City Clinical Hospital No. 5 of the city of Ufa, Ufa, Russian Federation
Published: October 2020

Aim: to assess clinical efficacy of azoximer bromide in the complex inpatient treatment for COVID-19. Patients and Methods: the study included 20 patients aged 16–65 years with verified moderate novel coronavirus infection who received inpatient care. All patients were divided into two groups. Study group patients (n=10) received complex treatment that included azoximer bromide. Control group patients (n=10) received standard therapy only. The criterion of treatment efficacy was the improvement of major disease symptoms, radiographic manifestations, and pro-inflammatory laboratory tests. Results: azoximer bromide as a component of the treatment for novel coronavirus infection provides more rapid symptom relief (i.e., cough, sputum, fever, respiratory rate) compared to the standard therapy (p<0.05). azoximer bromide also provides more rapid radiographic improvement as demonstrated by helical computed tomography, i.e., by day 14, the percentage of lung parenchyma involved was 5% in the study group and 10–12% in the control group (p<0.05). In addition, the improvement of pro-inflammatory laboratory tests (i.e., normal WBC count, decrease in ESR) was revealed as well (p<0.05). Conclusion: azoximer bromide as a component of the complex treatment for novel coronavirus infection is associated with the clinical improvement that manifests with more rapid relief of inflammation and lung parenchyma involvement as compared with the standard therapy. No adverse reactions were reported. KEYWORDS: coronavirus infection, SARS-CoV2, COVID-19, pneumonia, immune correction, pathogenetically-oriented therapy, azoximer bromide. FOR CITATION: Mukhamadieva L.R., Mavzyutova G.A., Tyurina E.B., Kuzovkina O.Z. Pathogenetically-oriented therapy for novel coronavirus infection. Russian Medical Inquiry. 2020;4(4):192–198. DOI: 10.32364/2587-6821-2020-4-4-192-198.
Pattern of facial beauty: previously undefined proportions
Authors:   I.P. Pavlov First St. Petersburg State Medical University, St. Petersburg, Russian Federation, Solov’ev M.M. ,   City Multidisciplinary Hospital No. 2, St. Petersburg, Russian Federation, Katinas E.B. ,   I.P. Pavlov First St. Petersburg State Medical University, St. Petersburg, Russian Federation, An I.A. ,   CJSC “Medical Center RAMI”, St. Petersburg, Russian Federation
Published: October 2020

Aim: to develop an universal cephalometric analysis of a beautiful female face and a simple method of the planning of orthognathic surgery for correcting malocclusions, improving airway permeability, and achieving a good stable esthetic outcome. Patients and Methods: to determine facial proportions, a term “rondist” (Ro) was introduced defined as a horizontal plane that corresponds with the natural line dividing a head into the upper and lower portions. Three planes being perpendicular to the rondist go through the subnasal point (Sn), glabella (Gb), and tuber frontale (Tf). LF is the lower one-third of the face. A profile depth (PD) is the ratio of Sn-Gb distance to Gb-Tf distance while a lower facial inclination (LFI) is the angle between LF and Ro (LF/Ro). 122 most beautiful female photos from various rankings were analyzed. All faces were allocated to either group 1 (modern Caucasian women, n=52), 2 (20th century Caucasian women, n=33), 3 (Mongoloid women, n=19), or 4 (Negroid women, n=18). Results: side portrait image was found for each face. PD and LFI were determined. PD and LFI were 0.97±0.016 93.3°±0.6° in group 1 (Gaussian distribution), 0.97±0.02 and 93.0°±0.8° in group 2, 0.96±0.02 and 93.6°±1.1° in group 3, and 0.97±0.03 and 92.6°±1.1° in group 4, respectively. Statistical analysis has demonstrated that all distributions belong to the same general population. Conclusion: the characterization of a novel facial plane (Ro) and cephalometric analysis revealed the race- and history-independent criteria of a beautiful face that are intuitively defined by most people. Beautiful faces follow the same template with PD equal to 1.0 and LFI closer to 90°. KEYWORDS: facial proportions, attractiveness, dental anomalies, sleep apnea. FOR CITATION: Solov’ev M.M., Katinas E.B., An I.A. Pattern of facial beauty: previously undefined proportions. Russian Medical Inquiry. 2020;4(4):226–232. DOI: 10.32364/2587-6821-2020-4-4-226-232.
Whole-exome Sequencing Reveals Genetic Underpinnings of Tongue Carcinoma in Chinese Population
Authors: Wang Shuhang , Jiang Ning , Yu Zicheng , Fang Yuan , Xing Shujun , Huang Huiyao , Yu Yue
Published: October 2020

Oral tongue squamous cell carcinoma (OTSCC) is a common malignancy, of which the incidence has increased in China in the last decade. Surprisingly, while multiple studies have revealed the mutational features of OTSCC in Western populations, limited data was shown in Asian patients. Herein, we utilized whole-exome sequencing to profile the genetic alterations in 13 Chinese OTSCC and compared them to those from 40 Western patients published in Cancer Discovery. In result, some key driver mutations were observed in both Chinese and Western cohorts, such as TP53 (Chinese 60.0% vs Western 60.0%), FAT1 (Chinese 7.7% vs Western 30.0%), CASP8 (Chinese 7.7% vs Western 10.0%) and NOTCH1 (Chinese 15.4% vs Western 10.0%), while mutations in CDKN2A (23.1%) and NTRK3 (23.1%) were only observed in Chinese patients, indicating these two novel mutations might play vital roles in OTSCC tumorigenesis specifically in Asian population. Mutational signatures depicted both common and distinct features across cohorts. In addition, significant copy number loss was found in 7q22.1, 9q13.1, and focal regions spanning CDKN2A and CDKN2B. FOXP1-TEX261 (2p13.3:3p13) fusion, reported in various cancer types, was firstly observed in OTSCC. Also, we identified numerous actionable mutations with FDA approved targeted. Taken together, our study revealed the mutational features of Chinese OTSCC patients, either similar or distinct to those of Caucasian patients. CDKN2A and NTRK3 were observed as two novel drivers that might play essential roles in tumorigenesis in Chinese patients, and were found as two potential therapeutic targets, rendering it promising to develop novel therapies.
ASPECTOS CONTROVERSOS DA PRISÃO PREVENTIVA PARA GARANTIA DA ORDEM PÚBLICA
Authors: Farias Jeanpier
Published: October 2020

O presente trabalho de conclusão de curso tem como escopo trazer à baila as questões atinentes ao instituto da prisão preventiva, fazer um paradoxo entre esta medida cautelar e o principio constitucional da presunção de inocência, e, por fim, fazer um crítica ao fundamento, mais discricionário, vago, e assim sendo, o mais usado pelos tribunais na sua decretação, qual seja a garantia da ordem pública. Por ser analisada e aplicada de maneiras distintas é que este tema enseja muitas controvérsias no âmbito jurídico e social. Procurando entender o modo como é utilizada a garantia da ordem pública como fundamento norteador para a decretação de uma prisão preventiva. Assim sendo, foi elaborada uma critica da aplicação da ordem pública utilizando-se de fontes doutrinárias e jurisprudenciais. Uma vez que, verificaram-se as mais variadas fundamentações na aplicação da garantia da ordem pública, todas carregadas de valores subjetivos, adotados conforme o critério ideológico de cada Magistrado. Parte-se então da análise da medida cautelar de prisão preventiva, expondo de forma mais detalhada o seu conceito, hipóteses, requisitos e fundamentos, em seguida um contraponto entre esta e principio da presunção de inocência. Para somente depois de estudado pontos importantes desses institutos, adentrar na garantia da ordem pública, o mais subjetivo e vulgarizado, fundamento desta medida que por muitos é considerada a mais penosa das medidas cautelares.
A IMPESSOALIDADE NA GESTÃO: UM PROBLEMA GERADO PELO CAPITALISMO?
Authors: Andrade Matheus , Sampaio Davi Oliveira
Published: October 2020

Propõe-se, neste artigo, um debate sobre a visão de autores que defendem que a impessoalidade na gestão é um problema gerado pelo capitalismo frente a análises históricas que demonstram que os gestores tinham características fortes de impessoalidade e traçava suas metas gerenciais visando estabelecê-las. A impessoalidade advém do capitalismo ou a mesma vem sendo cultivada ao longo da história, na qual o modelo econômico figura-se apenas como um objeto propulsor e não sua causa primária? Não seria a organização uma representação em menor escala da relação monopolística do uso da violência por parte de quem controla o poder legitimado dado ao Estado? Estado este que é analisado, estudado, conceituado desde quando o modo de produção Ocidental era Escravista Antigo. O pragmatismo excessivo na liderança de um grupo de pessoas é um “mal capitalista” ou uma habilidade inerente à raça humana? Os administradores veem na relação de monopólio da violência e da coerção adquiridos pelo Estado um modelo a ser seguido dentro de suas organizações. É mostrado, a seguir, como é formulada a individualidade e a indiferença para com o próximo, muito antes do surgimento do capitalismo. Quanto à metodologia, trata-se de um estudo exploratório, bibliográfico e descritivo.
A IMPORTÂNCIA DO PROFESSOR MEDIADOR NA ALFABETIZAÇÃO E LETRAMENTO DA EDUCAÇÃO BÁSICA
Authors: Nascimento da Silva Carine , Figueira Fontoura Mariana , Figueira Sabrina , Przylinski Marlene , Cauduro Peranzoni Vaneza
Published: October 2020

A presente pesquisa tem por objetivo analisar as diferenças dos métodos de alfabetização desenvolvidos em diferentes escolas. E tem como objetivos específicos identificar as características entre os diferentes métodos de alfabetização e compreender como se dá os diversos tipos de alfabetização em contextos diferentes. Nessa premissa, esta pesquisa trata-se de uma pesquisa de natureza descritiva, de abordagem qualitativa. A população da pesquisa foram quatro professores alfabetizadores. O instrumento da pesquisa foi um questionário semiestruturado, no qual os dados coletados foram analisados e a partir disso emergiram reflexões sobre o processo de alfabetização. Os resultados ratificam a importância do professor alfabetizador, bem como sua prática em sala de aula. Outro fator marcante é a compreensão de que os educadores necessitam de formação contínua, é desse modo que irão aprimorar sua prática. A partir do estudo, concluiu-se que o professor é o agente possibilitador e que os alunos de hoje serão o futuro de amanhã.
MÉTODOS QUANTITATIVOS APLICADOS NAS TOMADAS DE DECISÕES DENTRO DAS EMPRESAS
Authors: Orth Arlete Cherobini , Évelin Fernandes Luzia , Cristina Tonial Rafaela
Published: October 2020

A presente pesquisa “Métodos Quantitativos aplicados nas tomadas de decisões dentro das empresas” teve como objetivo geral, analisar um grupo de Empresas, localizadas nos municípios de Lucas do Rio Verde e Tapurah, no sentido da utilização de métodos quantitativos nas suas tomadas de decisões administrativas. O trabalho foi realizado com material bibliográfico e através de um questionário com dezesseis perguntas, nas quais, três (03) questionavam sobre características do entrevistado e as outras 13 (treze), relacionadas aos objetivos específicos do nosso trabalho; essas foram aplicados a contadores e administradores das empresas. Metodologicamente a nossa pesquisa envolveu uma abordagem indutiva e um estudo qualitativo. Para interpretar os dados foram utilizados gráficos e tabelas, as quais fazem a comparação das respostas fornecidas nos questionários. A realização deste estudo justificou-se pela necessidade de novos conceitos para elaboração de decisões que tendem a melhorar o desempenho da empresa.
Monitoring of Black Sea algal viruses Tetraselmis viridis and Phaeodactylum tricornutum in bays of Sevastopol as a component of ecological monitoring of the studied aquatories
Authors:   Institute of Natural and Technical Systems, Stepanova O.A.
Published: October 2020

Virus monitoring is a widespread control of their background circulation. Since 2002, the monitoring of algal viruses that infect microalgae Tetraselmis viridis and Phaeodactylum tricornutum has been carried out in the bays of Sevastopol differing in ecological conditions. The purpose of this work is to analyze and assess the results of this long-term (2002–2020) monitoring. The results obtained with taking into account the exactingness or resistance to environmental conditions of hosts of algal viruses that infect microalgae T. viridis and P. tricornutum were the basis for the following conclusions regarding the ecological well-being of the studied bays of Sevastopol: – relatively favorable ecological conditions in 2007–2008, 2017–2018 and in 2020. (maximum frequency of isolation PtV, and/or minimum TvV, and / or maximum difference in frequency of isolation between PtV and TvV); – unfavorable ecological conditions in 2002–2003, 2006 and 2015 (maximum frequency of isolation TvV, and/or minimum PtV, and/or maximum difference in frequency of isolation between TvV and PtV). Analysis of the monitoring results of algal viruses of T. viridis and P. tricornutum in 2015–2020 revealed that the studied relatively ecologically safe bays are characterized by the maximum number of all isolates of algal viruses (both TvV and PtV) and the numerical predominance of strains of algal virus of P. tricornutum, which is demanding to environmental conditions. At the same time, the minimum amount of all viral isolates was recorded in the ecologically unfavorable bay. The results of a long-term monitoring of algal viruses of T. viridis and P. tricornutum have established the possibility of using the monitoring of marine viruses, in particular of algal viruses of microalgae which are indicative of the ecological situation, as a component of complex ecological monitoring as ecological indicator.
Синфітоіндикаційне моделювання кліматопів лісових екосистем за даними моніторингу лісів лісостепової частини України
Authors: Bondaruk M. A. , Buksha I. F. , Tselishchev O. G.
Published: October 2020

Викладені в роботі методичні підходи синфітоіндикаційного моделювання й приклади їхнього застосування розкривають перспективність цього наукового напряму для регіонального (зонального) екологічного моніторингу кліматичних режимів лісових екосистем. Розроблено моделі клімафону (термо-, контрасто-, омбро- та кріофони) лісових екосистем Лісостепової лісогосподарської області та клімафонів хвойних, мішаних і листяних лісів; визначено тенденції динаміки фітоіндикаційних показників кліматичних режимів згідно зі змінами лісорослинних умов. Порівняння отриманої балової оцінки в різні часові періоди (наприклад, раз на 5 років) у кожному регіоні України дасть можливість оцінювати інтенсивність, глибину, спрямованість (тренд), просторовий розподіл та особливості зміни кліматичних режимів унаслідок впливу кліматичних змін на лісові екосистеми України на регіональному та національному рівнях, що є важливою складовою моніторингу лісових екосистем в умовах зміни клімату. Об’єкти досліджень – 642 ділянки моніторингу лісів I рівня в межах Лісостепової лісогосподарської області України.
Вплив кореневої губки на ріст, структуру та санітарний стан соснових насаджень, створених на староорних землях у Лісостепу Харківської області
Authors: Mykhailichenko O. A. , Ustsky I. M. , Gnoevy I. V.
Published: October 2020

Одним із найнебезпечніших збудників хвороб хвойних лісів є коренева губка (Heterobasidion annosum (Fr.) Bref.). Всихання насаджень, уражених кореневою губкою, відбувається нерівномірно, тому їх можна умовно розподіляти на фрагменти, що мають різні стан, лісівничо-таксаційні показники та швидкість росту: осередок всихання, міжосередковий простір та еталонна частина міжосередкового простору. Встановлено, що за розподілом кількості стовбурів за ступенями товщини різні фрагменти уражених кореневою губкою насаджень належать до різних генеральних сукупностей. Виявлено, що в Лівобережному Лісостепу густота штучних соснових насаджень ІІІ–Х класів віку, створених на староорних землях і уражених кореневою губкою, в осередках усихання є достовірно меншою, ніж у міжосередковому просторі та еталонній частині міжосередкового простору (на 1–31 та 24–50 % відповідно). Середні висота й діаметр дерев, що ростуть в осередку всихання, є меншими на 1,6 та 1,8 % відповідно проти висоти й діаметра дерев, що ростуть у міжосередковому просторі, та на 5,2 та 3,7 % – проти відповідних показників еталонної частини міжосередкового простору. Визначено, що уражена частина соснового насадження – осередок всихання та міжосередковий простір – за станом є ослабленою та всихаючою: індекс санітарно стану становить від 2,0 до 3,7 та від 1,8 до 3,4 для осередку всихання та міжосередкового простору відповідно. Не уражена кореневою губкою частина насадження (еталонна частина міжосередкового простору) має ослаблений та сильно ослаблений санітарний стан через загущеність і відсутність рубок догляду. Запас ураженого кореневою губкою насадження залежить від поширення осередків усихання та від площі, яку займають власне осередки хвороби, міжосередковий простір та еталонна частина міжосередкового простору.
Економічна оцінка запасів деревостанів та віків стиглості соснових і дубових насаджень
Authors: Torosov A. S , Zhezhkun I. M. , Kalashnikov A. O. , Kharchenko Yu. V.
Published: October 2020

Наведено методику економічного оцінювання деревостанів за чинними та проєктними віками стиглості з урахуванням актуального поділу лісів за категоріями, класами бонітету та походженням. Визначено показники загальних запасів деревостанів та їхнього розподілу за розмірно-якісними категоріями деревини в певному віці проведення рубок головного користування за чинними та проєктними віками стиглості. Розраховано площі та проведено грошове оцінювання запасів деревини стиглих деревостанів сосни звичайної та дуба звичайного за віками стиглості (2010–2040 рр.) на прикладі державних лісогосподарських підприємств Харківської та Чернігівської областей. Порівняно вартісні показники запасів деревостанів сосни й дуба у віці стиглості на перспективу до 2040 р. Обґрунтовано економічну доцільність застосування вартісних показників для визначення віків стиглості деревостанів.
Вплив регуляторів росту рослин на ріст сіянців сосни звичайної в умовах відкритого ґрунту (ДП «Київська ЛНДС»)
Authors: Savuschyk M. P. , Khromulyak O. I. , Shlonchak G. A. , Yashchuk I. V.
Published: October 2020

Наведено результати досліджень впливу регуляторів росту рослин на якісні показники насіння й ростові характеристики сіянців сосни звичайної (Pinus sylvestris L.). Дослідження проводили у відкритому ґрунті розсадника ДП «Київська лісова науково-дослідна станція». Для дослідів використано препарати Епін екстра, Гумат ультра, Мегафол і Стімпо. Вплив регуляторів росту рослин на насіння досліджували методом його передпосівного оброблювання водними розчинами препаратів. Регулятори росту рослин застосовували обприскуванням і поливанням сходів від час вирощування сіянців. Встановлено, що із випробуваних препаратів найбільший стимулювальний ефект для пророщування насіння сосни звичайної виявив препарат Стімпо. Підживлення сіянців регуляторами росту рослин сприяло збільшенню біометричних і вагових показників. Максимальне достовірне перевищення висоти, діаметра кореневої шийки, довжини коренів і середньої маси одного сіянця над контролем відзначено в результаті використання препарату Мегафол. Проведені дослідження свідчать про доцільність застосування препарата Стімпо для підготування насіння до висівання й біостимулятора Мегафол – під час вирощування сіянців сосни.
The Analysis of Factors Associated with the Effectiveness of Nurse Communication to Patients in the Inpatient Room of Teungku Fakinah Hospital, Banda Aceh
Authors: Saputra Muhammad Iqbal , Usman Said , Sofia Sofia , Saputra Irwan , Yusni Yusni
Published: October 2020

The aim of thisstudy is to find out the factors relating to the effectiveness of nurses communication in patient. The type of research in this study is quantitative analytic with cross sectional study approach. The research location is in the inpatient room of Teungku Fakinah Hospital in Banda Aceh. The result of the study are the effectiveness of nurse communication in patients at Teungku Fakinah Hospital is in the category of good at 89%, the value of the variables of openness, empathy, equality, audible (humble) and humble (humble) are in good category that is above 95%, factors that significantly affect the effectiveness of nurse communication in patients at Teungku Fakinah Hospital, namely the openness of empathy level, the level of equality of the audible level (right) and the level of humble (humble). The better the level of openness, the better the effectiveness of nurse communication in patients. The better the level of empathy, the better the communication effectiveness of nurses in patients. The better the level of equality, the better the effectiveness of nurse communication in patients.The better the level of audible (right), the better the effectiveness of nurse communication in patients.The better the level of humble (humble), the better the effectiveness of nurse communication in patients.
Parasympathetic Nerve Function Status in Major Depressive Disorder Patients and Its Correlation with Duration of Disease
Authors: Jahan Choudhury Rifat , Uddin Md Moyeen , Uddin Md Samir , Hoq Chowdury Misbah Ul , Wajeunnesa - , Naher Mahmuda Quamrun
Published: October 2020

Introduction:Cardiovascular (CV) morbidity is a major problem in patients suffering from depression. Greater CV mortality is found in cardiac patients with depression than without depression. Depressive disorder can cause altered autonomic nerve function. This study design to assess autonomic nerve function activity by heart rate variability analysis in patients with major depressive disorder and its correlation with duration of disease.

Materials and Methods: This case study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka in 2011. 60 patients of both sexes with major depressive disorder (MDD) aged from 20-50 years were included in the study group (Group B). The patients were selected from out and inpatient Department of Psychiatry in Bangabandhu Sheik Mujib Medical University (BSMMU). Group B were divided into B-1 consisting of 30 drug naive MDD patients & B-2 consisting of 30 medicated MDD patients. For comparison age and sex matched 30 apparently healthy subjects (Group A) were also studied. The HRV parameters were recorded by 4 active channels, Polyrite-D machine. For statistical analysis ANOVA, independent sample t-test, chi-square test and Pearson’s correlation coefficient test were performed by using SPSS for windows version-16 as applicable.

Results: Mean resting pulse rate, mean heart rate, systolic blood pressure were significantly higher in drug naive and medicated MDD patients in comparison with that of healthy control. Mean R-R interval, Max/Min R-R interval, SDNN, RMSSD, PNN50%, NN50% were significantly lower in this groups of patients. Correlation analysis showed negative correlations of SDNN, RMSSD, PNN50%, NN50% with disease duration which was statistically significant only for SDNN.

Conclusion: Sympathovagal imbalance may occur in both drug naive and medicated MDD patients which is associated with higher sympathetic and lower vagal modulation of the heart rate. In addition, parasympathetic nerve function parameters show negative relationship with the duration of disease.

Medicine Today 2020 Vol.32(2): 76-80
Coronavirus-A Global Emergency
Authors: Ahad Md Abdul
Published: October 2020

Introduction:Coronavirus is a highly infectious contagious virus producing pandemic throughout the world with highmorbidity and mortality.

Discussion: Right now, there is no vaccine to prevent human coronavirus infections. But you mayable to reduce your risk of getting or spreading an infection by-washing hands often with soap and water for at least 20seconds, use an alcohol-based hand sanitizer that contains at least 70% alcohol if soap and water are not available. Avoidingtouching your face, nose, or mouth with unwashed hands, use of face mask, avoiding close contact with people who aresick, there is no specific treatment for coronavirus.

Conclusion:Treatment aims to relieve the symptoms. Most people willget better on their own. However, you can relieve your symptoms by-taking over-the-counter medicines for pain, fever, andcough. Using a room humidifier or taking a hot shower to help ease a sore throat and cough. Getting plenty of nutritiousdiet, drinking fluids and taking rest.

Medicine Today 2020 Vol.32(2): 138-142
Lung ultrasound and biomarkers in primary care: Partners for a better management of patients with heart failure?
Authors: Domingo Mar , Conangla Laura , Lupon Josep , Wilke Asunción , Juncà Gladys , Revuelta-López Elena , Tejedor Xavier , Bayes-Genis Antoni
Published: October 2020

Introduction: The association of pulmonary congestion assessed by lung ultrasound (LUS) and biomarkers—other than N-terminal pro-brain natriuretic peptide (NT-proBNP)—is uncertain.

Methods: We investigated the relationship between total B-line count by LUS and several biomarkers in outpatients with suspicion of heart failure (HF). Primary care patients with suspected new-onset nonacute HF were evaluated both with a 12-scan LUS protocol (8 anterolateral areas plus 4 lower posterior thoracic areas) and 11 inflammatory and cardiovascular biomarkers. A cardiologist blinded to LUS and biomarkers except NT-proBNP confirmed HF diagnosis. After log-transformation of biomarkers’ concentrations, unadjusted and adjusted correlations were performed.

Results: A total of 170 patients were included (age 76 ± 10 years, 67.6% women). HF diagnosis was confirmed in 38 (22.4%) patients. After adjustment by age, sex, body mass index, and renal function, total B-line sum significantly correlated with NT-proBNP (R = 0.29, p < 0.001), growth/differentiation factor-15 (GDF-15; R = 0.23, p = 0.003), high-sensitive Troponin T (hsTnT; R = 0.36, p < 0.001), soluble interleukin-1 receptor-like 1 (sST2; R = 0.29, p < 0.001), cancer antigen 125 (CA-125; R = 0.17, p = 0.03), high-sensitivity C-reactive protein (hsCRP; R = 0.20, p = 0.009), and interleukin (IL)-6 (R = 0.23, p = 0.003). In contrast, IL-33 (R = −0.01, p = 0.93), IL-1β (R = −0.10, p = 0.20), soluble neprilysin (sNEP; R = 0.09, p = 0.24), tumor necrosis factor-alpha (TNF-α; R = 0.07, p = 0.39), and TNF-α receptor superfamily member 1A (TNFRSF1A; R = 0.14, p = 0.07) did not.

Conclusions: Total B-line sum correlated significantly, although moderately, with congestion and several inflammation biomarkers. Unexpectedly, the highest correlation found was with hsTnT.
Correção de assimetria facial em indivíduo adulto com disjunção palatal unilateral assistida por miniparafusos (MARPE) - Nova Técnica: Relato de caso
Authors: Homem Neto Edson
Published: October 2020

Introdução: Um dos primeiros problemas a serem tratados nas desordens oclusais, é a correção transversal que pode envolver uma mordida de topo, cruzada uni ou bilateral. Essas atrésias, muitas vezes, podem contribuir nas correções estéticas do sorriso, incluindo assimetrias da face. Objetivo: Visando à correção das assimetrias faciais com a expansão rápida da maxila apoiada em miniparafusos, este trabalho demonstra uma nova técnica por meio da fragilização e expansão unilateral da maxila que facilita o retorno da mandíbula deslocada para o lado ipsilateral da expansão. Relato de caso: Com a utilização de corticoperfurações realizadas na rafe palatina, como já sugerido na literatura, e complementadas também na região de crista infrazigomática no lado oposto à assimetria facial, isso favoreceu o deslocamento mandibular para o lado da expansão, corrigindo assim a estética da face. Considerações Finais: A presente abordagem de fragilização da crista infrazigomática, com o intuito de maior deslocamento de uma hemimaxila para o lado oposto ao desvio facial, pode facilitar algumas correções não cirúrgicas de indivíduos assimétricos.
Efeito do mecanismo sulcador e densidade de plantas na cultura da canola, na resistência a penetração e na cultura da soja subsequente
Authors: Milla Felipe , Rampim Leandro , Harmatiuka Pedro Henrique , Regiani André Luiz Maziero , Muller Marcelo Marques Lopes , Faria Vanessa de Oliveira , Pacheco Amanda Alvea , Olanik Chaiane , Bini Pamela Estyse Campos
Published: October 2020

A canola (Brassica napus L.) se apresenta como cultura invernal economicamente e agronomicamente interessante para produtores sul brasileiros. Há questionamento sobre a tecnologia de implantação da cultura. Assim, o objetivo neste trabalho foi avaliar o sistema de sulcamento para distribuição de adubo e da população de plantas na implantação da canola, e seus efeitos na resistência do solo à penetração e na cultura da soja subsequente. Foram utilizadas duas populações de canola (20 e 40 plantas m-2) e dois sistemas sulcadores (facão e disco duplo) com seis repetições em blocos ao acaso. Semeou-se com uma semeadora pneumática de precisão com espaçamento de 50 cm entre linhas. Na canola as variáveis avaliadas foram: Número de plantas por metro linear (NP), Massa de mil sementes (MMS), Produtividade (P), Comprimento de raiz (CR), Volume de raiz (VR), Massa seca de parte aérea (MSPA), Massa seca de raiz (MSR) e resistência à penetração (RP). Na soja foi quantificado a Produtividade, a Massa de mil sementes e o Diâmetro de Caule (DC). A população de 40 plantas m-2 proporciona maior produtividade, independente do sistema de sulcamento. O sulcador em facão promoveu maior CR, e menores MSPA e MSR. Há menor RP na linha de semeadura ao utilizar haste sulcadora, após implantação da canola. O manejo da canola, nos quesitos população e sistema de sulcamento, não afetaram a soja implantada na sequência.