bluuebunny/crossref_metadata_2025 huggingface dataset:
Considerations for nursing research after the COVID-19 pandemic
Authors: McKenna Lisa
Published: December 2023

The COVID-19 pandemic impacted on nursing in a variety of ways. Many parts of the world experienced long-term lockdowns and what work could be done remotely was undertaken that way. For those nurses engaged in research activities, particularly clinical nursing research, it presented immense challenges. Questionnaire-based research had to be moved exclusively online, while interview-based research was managed using videoconference facilities and making some qualitative research approaches requiring participant observation more difficult. Being able to recruit participants for research was further challenged as researchers were unable to recruit in person and needed to resort to a multitude of online approaches such as using social media platforms. As a result of impacted recruitment, many researchers needed to report their research as being unable to meet quality measures such as sample size calculations or data saturation. This particularly impacted research students with time pressures to complete, and report on, their studies. Similarly, they needed to acknowledge in their study limitations how the pandemic had impacted on their research.
Optimizing of Library Management Based 5S Method (Case Study: Buluh Cina Village, Kampar District, Riau)
Authors: Masnur Dedy , Romy  , Syafri  , Yohanes  , Susilawati Anita , Putra Andi
Published: December 2023

This community service activity aims to develop and improve library management using the 5S method and computerised system of books inventory to increase community literacy in Buluh Cina Village, Kampar Regency, Riau Province. The optimal and efficient library, such as book collections, library users, facilities, infrastructure, and library management, can be appropriately managed based on the 5S method and book inventory-based computerisation. The 5S method (Seiri, Seiton, Seito, Seiketsu and Shitsuke) was adopted to organise library rooms by arranging bookshelves, catalogue cabinets, reading tables, and other equipment. By applying the 5S method, a more optimal inventory management system and book borrowing were obtained easily. The existence of this system makes it easier for officers to put back the books that have been read in their original place. Replacing books can be done quickly; the librarian only needs to input the book code, book data and shelf locations for storage displayed. The book was inventory-based computerised, which made it more accessible to detect the number of collections, the presence of books on storage shelves, a monitoring system for book borrowers, and additional collections. Therefore, the management and services of the library are optimal and lead to the visitors' satisfaction.
The Village Empowerment Through Circular and Green Economic Programs Through Independent Waste Management
Authors: Ratri Wahyu Setya , Astuti Ari , Permatasari Desy Ayu Irma
Published: December 2023

Tofu and organic waste are problems that are high on the agenda in Yogyakarta, especially in Sleman and Bantul. This area is also the largest center of the tofu industry and essential oil from red lemongrass in DIY. Through the Community Service (Abdimas) program in collaboration with Rumah Maggot Barepan Bangkit (RMBB) and the Sereh Merah Farmer Group in the Integrated Community Service Program program with MBKM Based on IKU for Private Universities in 2022-2023 in collaboration with the Directorate of Research, Technology, and Community Service Kemdikbudristek, UST Faculty of Agriculture and Faculty of Pharmacy Duta Bangsa University, try to empower the community with circular and green economiy activities the waste becomes money. This activity aims to increase the capacity of the community to become an independent waste processing center, teaching the processing of lemongrass leaves into fertilizer, processing maggot into pellets, processing and packaging kasgot into fertilizer and planting media. This service is divided into three stages, taking place from 2022 - 2023. The activities are divided into three stages. The first stage is socialization of independent lemongrass waste management, introduction of soil improver factors, and processing maggot into pellets.The second stage is a workshop on making POC and biofertilizer made from lemongrass, processing maggot into pellets, processing kasgot into fertilizer and planting media.The third stage is practice and application, making biofertilizer, POC, and floating pellets in the two fostered communities. It is hoped that this service will create a circular economy where the community can manage waste independently, get benefits from waste management and economic turnover in the village. In addition, it will create a green economy, where there is no more waste generated from the activity and the waste becomes money.
The Impact of Positive Emotions of Purchasing Mediated Sales Promotion for Lifestyle and Hedonic Shopping Motivation
Authors: Kuncoro Amin , Samekto Agus AJi , Astuti Widji -
Published: December 2023

The aim of this research is to examine and analyze sales mediation promotions on the effect of lifestyle and hedonic shopping motivation on positive emotions. The research design uses a quantitative descriptive research with causality. The population and sample are students who use online purchasing applications in the City of Kudus, totaling 248 respondents. The results of the study explain that promotion mediates sales on the influence of lifestyle and hedonic shopping motivation. Because the role of sales promotion thereby increasing positive emotions. This proves that in essence sales promotion, especially sales using online applications, is able to foster hedonic shopping motivation.
Osteolysis After Augmented Scapholunate Ligament Reconstruction
Authors: Lee Ellen Y. , Shin Alexander Y.
Published: December 2023

Case:

Augmented scapholunate ligament reconstruction using polyether ether ketone anchors and ultra-high molecular weight polyethylene synthetic tape has the theoretical advantage of improved stability, avoidance of K-wire fixation, and the potential for earlier mobilization. We present 3 cases of scaphoid and lunate osteolysis/fragmentation, operative and histologic findings at reoperation, and the sequelae of this technique.

Conclusion:

If planning to use suture anchors and synthetic tapes in small carpal bones, we recommend advising patients about the risk of osteolysis and monitoring closely patients who complain of pain with motion after surgery.
Peran Bank Wakaf Mikro dalam Meningkatkan Kesejahteraan Masyarakat di Papua: Pendekatan Maqshid Syariah
Authors: Putri Oggy Maulidya Perdana , Marasabessy Masaalah
Published: December 2023

The establishment of the Micro Waqf Bank offers a viable approach for mitigating poverty and enhancing the quality of life for individuals.   The Micro Waqf Bank aims to enhance individuals' quality of life by offering access to sharia-compliant financial services and business support.   The objective of this study is to elucidate the function of the Honai Sejahtera Papua Micro Waqf Bank in enhancing customer well-being from the standpoint of Maqashid Syariah.   This study employs a descriptive qualitative research design, utilising primary data collected through interviews and recording.   This research involves the process of data analysis, which encompasses data gathering, data reduction, and the derivation of conclusions.   The findings of this study demonstrate that the Honai Sejahtera Papua Micro Waqf Bank plays a significant role in achieving the well-being of its customers. This is evidenced by the community's capacity to uphold religious values, safeguard their spiritual well-being, preserve their rationality, ensure the welfare of their descendants, and protect their assets.
Word of Mouth or Online Services: What is the Best Determinant of Muzakki’s Preference in Selecting Zakat Agency?
Authors: Pusparini Martini Dwi , Zahroh Nur Azizah Zuhriah
Published: December 2023

The number of national-level zakat institutions has decreased since the implementation of Zakat Law Number 23 of 2011, indicating a more organized zakat administration. Nevertheless, in reality, many muzakki still opt not to distribute their zakat through the existing Zakat Management Organizations (OPZ) in Indonesia. Instead, they prefer to directly give zakat to their chosen mustahik. Despite the importance of paying zakat through zakat institutions, it is crucial to comprehend individuals' preferences in this regard. The main objective of this study is to investigate the factors influencing muzakki's preferences for zakat institutions, including trust, word of mouth, and online services. The research is based on empirical data gathered from 132 respondents in Central Java. Multiple linear regression was employed to test the study hypotheses. The findings reveal that all the examined variables, namely trust, word of mouth, and internet services, significantly influence muzakki's choices for zakat institutions. Further analysis indicates that among these factors, online services play the most significant role in shaping muzakki's preferences. The limitation of the study lies in the research sample where Indonesia consists of 34 provinces and only 1 province is involved in this study. This study presents a summary of the relevance of online services in zakat institutions, as previous research on muzakki preferences on zakat payment has never included online service factor.
ANALISIS KELAYAKAN PENGEMBANGAN USAHA NATA DE COCO PADA CV AMARTA KECAMATAN KEMPAS KABUPATEN INDRAGIRI HILIR
Authors: Wahyuni Putri
Published: December 2023

Nata de coco is a food product made from coconut water.  Nata de coco processing business has the potential to be developed because it can utilize coconut processing by-products.  This research aims to analyze the feasibility of developing a nata de coco business at CV Amarta in terms of financial and nonfinancial aspects so that it can be declared a feasible or infeasible business.  The research methods used were surveys to analyze nonfinancial aspects of the market, technical, management, legal, and environmental which are described descriptively and analyzed financial aspects based on investment criteria such as BEP, NPV, IRR, B/C ratio, payback period, and sensitivity analysis.  The nata de coco business development at CV Amarta is feasible in terms of nonfinancial and financial aspects with the results of BEP 528,176 units, BEP acquisition Rp 1,056,352,623, the value of NPV is Rp 166,216,342, IRR 16%, payback period 4.7 years, and B/C ratio 1.10.  The sensitivity analysis shows this business development is sensitive with 5% decrease in selling price and 5% increase in variable cost.
SIFAT FISIK DAN MEKANIK BIOPLASTIK DARI PATI KULIT PISANG AMBON (Musa paradisiacal) DENGAN PLASTICIZER SORBITOL
Authors: Putra Endo Pebri Dani
Published: December 2023

Bioplastic is one solution to the large amount of plastic waste that is a problem for the environment because it is difficult to degrade. This study aims to characterize the bioplastic film of ambon banana peel starch and to determine the best ambon peel starch concentration. Observations on the resulting bioplastic products are physical properties and mechanical properties. Physical properties tests include thickness, density, water absorption and mechanical properties including tensile strength, percent elongation, young's modulus. The results showed that differences in starch concentration affected the thickness, density, water absorption, tensile strength, elongation and young's modulus. The best treatment based on the mechanical properties of bioplastics was the addition of 1 g of Ambon banana peel starch.
EVALUASI PENERAPAN CARA PRODUKSI PANGAN OLAHAN YANG BAIK DI LIVIA CATERING YOGYAKARTA
Authors: Kumalasari Ika Dyah , Putri Citra Mutiara
Published: December 2023

Keamanan pangan (food safety) merupakan hal yang sangat penting untuk mencegah penyakit akibat pangan. Karena pangan yang aman, berkualitas dan minim pencemaran dapat diwujudkan oleh industri pangan dengan pengolahan yang baik dan pengelolaan lingkungan yang bersih. Pada industri kecil seperti catering, biasanya seringkali tidak konsisten dengan menerapkan cara pengolahan pangan yang baik dan terjamin kualitas serta keamanan mutu dari pangan tersebut. Data diperoleh melalui wawancara, observasi dan dokumentasi serta pengisian checksheet berdasarkan Peraturan Menteri Perindustrian RI No. 75/MIND/PER/2010, kemudian dianalisis faktor penyebab ketidaksesuaiannya dengan menggunakan diagram fishbone. Berdasarkan analisis, dapat diketahui bahwa terjadi penyimpangan CPPOB pada 7 dari 18 aspek. Penyimpangan tersebut terdiri dari aspek bangunan dan ruang Produksi, fasilitas sanitasi, produk akhir, laboratorium, karyawan, pemeliharaan dan program sanitasi, serta pelaksanaan pedoman. Dari 7 aspek tersebut diketahui adanya 12 ketidaksesuaian dengan persentase 15,7%. Aspek yang sudah sesuai meliputi lokasi/tempat produksi, mesin/peralatan, bahan, pengawasan proses, pengemasan, label, penyimpanan, pengangkutan, dokumentasi dan pencatatan, pelatihan karyawan dan penarikan produk. Persentase yang dihasilkan dari aspek kesesuaian yaitu 84%. Kendala yang menghambat dalam penerapan CPPOB yaitu manusia, prosedur dan fasilitas.Kata kunci:  CPPOB, Checksheet, Diagram Fishbone
PEMANFAATAN SAMPAH PLASTIK JENIS HDPE DAN PET SEBAGAI BAHAN BAKU PEMBUATAN BAHAN BAKAR MINYAK ALTERNATIF MENGGUNAKAN METODE PIROLISIS DENGAN KATALIS ZEOLIT ALAM
Authors: Kartika Wahyu
Published: December 2023

Sampah plastik sampai saat ini masih menjadi permasalahan lingkungan serius, seiring dengan pertumbuhan ekonomi dan meningkatnya jumlah penduduk. Plastik merupakan bahan  anorganik yang sukar terurai secara alamiah sehingga  diperlukan alternatif pengolahan untuk mengurangi volume sampah plastik. Salah satu cara adalah dengan memanfaatkan sampah plastik sebagai bahan baku pembuatan bahan bakar minyak alternatif dengan metode pirolisis.  Hal ini dapat dilakukan karena plastik merupakan produk turunan dari minyak bumi sehingga mempunyai nilai kalor cukup tinggi seperti bahan bakar komersial yang ada. Pirolisis adalah proses perekahan atau pemecahan rantai polimer menjadi senyawa yang lebih sederhana melalui proses termal dengan, tanpa maupun sedikit oksigen. Tujuan dari penelitian ini untuk mengetahui komposisi berat bahan baku, berat katalis, suhu dan waktu  reaksi optimal dalam  pembuatan bahan bakar minyak alternatif dari sampah plastik campuran HDPE dan PET menggunakan metode pirolisis dengan bantuan katalis zeolit alam serta kualitasnya sesuai istandar mutu minyak iKeputusan Dirjen Migas. Hasil penelitian diperoleh bahwa kualitas minyak pirolisis dengan  komposisi optimal berat bahan baku sampah plastik HDPE dan PET 500 g, katalis zeolit alam 200 g,suhu 4000C dan waktu reaksi 30 menit masuk dalam rentang standar minyak disel sesuai iKeputusan iDirjen iMigas I No. .28.K/10/DJM. iT/2016, dengan hasil uji laboratorium parameter  viskositas 3,02 mm2/s , densitas 851,2 kg/m3, nilai kalor 10.228,8 kcal/kg, titik didih 2150C dan kadar air 288 mg/kg. Kata kunci: Sampah Plastik; Bahan Bakar Minyak Alternatif;  Pirolisis; Katalis Zeolit
KAJIAN POTENSI DAN ANALISIS BIAYA PADA PEMBUATAN HAND SANITIZER EKSTRAK DAUN WARU (HIBISCUS TILIACEUS)
Authors: Sartika Dewi , Ayunisa Puan Mutia , Susilawati Susilawati
Published: December 2023

Hand sanitizer merupakan cairan pembersih tangan yang memiliki kandungan antiseptik sehingga mampu menghambat serta membunuh bakteri pada tangan. Kandungan alkohol pada hand sanitizer berperan sebagai antiseptik. Alkohol dapat menyebabkan kulit kering hingga iritasi jika digunakan secara terus menerus dalam jangka panjang. Salah satu alternatif dalam mengurangi alkohol pada hand sanitizer dapat dilakukan dengan menggunakan ekstrak tumbuhan yang mengandung antimikroba alami. Ekstrak daun waru terbukti memiliki aktivitas antimikroba S. Aureus, S. Epidermis, dan Escherichia coli. Adapun, tujuan penelitian ini untuk mengetahui potensi dan analisis break even point (BEP) pada hand sanitizer waru. Rancangan analisis usaha dilakukan untuk mengetahui kelayakan usaha yang ditinjau dari modal tetap, modal kerja, investasi, biaya tetap, total biaya, dan pendapatan. Pendapatan yang dihasilkan berasal dari daun waru yang diolah menjadi hand sanitizer ekstrak daun waru. Hasil dari penelitian ini yaitu rata-rata pendapatan pada produk hand sanitizer ekstrak daun waru dalam satu kali produksi sebesar Rp 2.351.000,00 pada tingkat penjualan hand sanitizer ekstrak daun waru sebanyak 43 botol dengan harga Rp3.245,24 maka pemilik usaha akan mencapai titik impas.
PEMETAAN KEHALALAN PRODUK PELAKU UMKM KECAMATAN SUKASARI KOTA BANDUNG
Authors: Zahradika Afuan , Permadi Dodi
Published: December 2023

Sertifikasi halal sangat penting dalam memastikan dan menjaga produk halal mulai dari produksi hingga konsumsi. Namun, dalam prosesnya memiliki beberapa kendala diantaranya pengetahuan yang belum begitu dipahami dan diterapkan khususnya bagi para pelaku UMKM, karena kurangnya perhatian dari berbagai pihak. Oleh karena itu, penelitian ini dilakukan untuk mengidentifikasi pengetahuan halal produk dan bahan baku yang digunakan serta memberikan rekomendasi atau usulan penerapan konsep halal untuk mendapatkan sertifikasi halal bagi para pelaku UMKM. Penelitian ini dilakukan di wilayah Kota Bandung dengan spesifik di wilayah Kecamatan Sukasari. Metode yang digunakan dalam penelitian ini adalah metodologi kualitatif dengan studi pustaka, wawancara sebagai metode pengumpulan data dan studi kasus sebagai teknik analisis, serta dikaitkan dengan aturan dan kebijakan yang berlaku di Indonesia. Hasil penelitian dari jumlah 53 pelaku UMKM (10% dari populasi) di wilayah Sukasari menunjukkan bahwa bahan baku yang digunakan oleh para pelaku UMKM mayoritas menggunakan bahan baku yang memiliki sertifikasi halal, namun tidak semua yang berstandar halal. Meskipun semua pedagang mengetahui pentingnya sertifikasi produk halal, hanya sebagian kecil yang berusaha untuk menjaga kehalalan produknya, oleh karena itu diperlukan sinergi antara pelaku usaha, Pemerintah atau Lembaga terkait dan konsumen untuk meningkatkan kesadaran terhadap pentingnya produk halal.
HALAL TRACEABILITY SYSTEM (HTS) UNTUK INTEGRASI HALAL MEAT SUPPLY CHAIN (HMSC) TERHADAP PROSES INDUSTRI DAGING AYAM PADA RUMAH POTONG HEWAN
Authors: Siregar Muhammad Lutfi , Zahradika Afuan
Published: December 2023

Konsep integrasi makanan halal mengharuskan logistik memainkan peran kunci dalam melindungi status halal produk melalui transportasi, penyimpanan dan penanganan barang yang tepat dalam rantai pasokan dari titik awal hingga mencapai tujuan akhir, kemudahan dalam Penelusuran produk menjadi salah satu cara untuk memastikan integrasi kualitas makanan halal tetap terjaga, maka dari itu sistem penelusuran menggunakan teknologi terkini seperti IoT, RFID, Barcode, dan Cloud  menjadi salah satu cara yang tepat untuk penelusuran daging ayam dari titik awal (peternak) hingga titik akhir (konsumen). Penelitian ini terfokus pada sistem penelusuran di rumah potong hewan dengan menggunakan pendekatan model SCOR untuk menentukan aktivitas pada rumah potong hewan kemudian memberikan rekomendasi model Halal Traceability System (HTS) untuk menjaga integrasi kualitas kehalalan daging ayam.
PENGARUH PRETREATMENT BAHAN KIMA DAN BIOLOGI TERHADAP AKUMULASI VOLUME BIOGAS DARI LIMBAH MAKANAN
Authors: Permadi Adi
Published: December 2023

In daily activities can produce garbage commonly called household waste. Food waste is included in household waste that has an impact on the environment. Household food waste has the potential to release methane gas into the environment causing damage to the earth's ozone layer because it includes greenhouse gases that can cause climate change. The increasing impact of food waste requires serious efforts to deal with the processing of household food waste. One of the efforts to overcome this is to mix household waste with cow dung to make biogas. In addition, it is also an effort to reduce fossil energy sources with renewable energy sources from biogas. This study aims to knowing the influence of chemical pretreatment (Ethanol, NaoH, and HCl) and Biology (EM-4 enzyme) at concentrations of 8%, 10% and 12% on the accumulation of biogas from food waste (rice and vegetables) produced for 30 days. While the pre-treatment results using chemicals (ethanol, HCl and NaOH) and biological materials (EM-4 enzymes) at concentrations of 8%, 10% and 12% provide a larger volume of biogas accumulation for 30 days, compared to raw materials. biogas that does not get pre-treatment. From this study, the pretreatment of biogas raw materials using 10% NaOH provided the highest accumulation of biogas volume (70 ml) in 30 days compared to other pretreatments.
APPLICATION OF ENGINEERING MANAGEMENT IN DEVELOPING THE LOCAL FOOD INDUSTRY SPICE COFFEE
Authors: Arifianto Endra Yuafanedi
Published: December 2023

The micro-scale food industry has a significant role in maintaining regional economic stability during a pandemic. The ability of food industry players to take advantage of community needs and the availability of natural resources is the key to growing business in this sector. One of the micro-scale food industries that has been able to grow during the pandemic and is mushrooming in several regions today is the spice coffee industry. Changes in the business model took place very quickly during the pandemic to support the availability of food, especially herbal products. Society needs coffee spices as an alternative supplement to help the immune system. This study uses an engineering management approach in explaining the concept of developing a local spice coffee food business. The results of applied engineering management include marketing research, business management engineering, and digital technology. Advances in digital technology, limited conditions of direct interaction, easy access to information, and high demand in the market have forced the spice coffee food industry to collaborate with various parties in developing new business models.

Keywords: food industry, spice coffee, engineering management, digital technology, food
A STUDY OF BENEFIT AND COST ANALYIS OF THE COMPOSTING AND THERMAL DECOMPOSITION FOR ORGANIC WASTE MANAGEMENT
Authors: Firmansyah Raden Arief , Hidayat Khoirul
Published: December 2023

Awareness of Indonesian people about waste management is low, specifically in organic waste management. Organic waste management is relatively easy. On the other hand, the community or person always chooses open dumping and open burning. These techniques are not sustainable actions, for the environment, even for living things. Waste could be managed sustainably, i.e., composting and thermal decomposition (pyrolisis). Composting produces organic fertilizer that is saleable and profitable. Thermal decomposition (pyrolysis) potentially have three product, bio-oil, bio-char, and syngas. These products are marketable and promising too. This research aims to study the potential application of composting and thermal decomposition technology on a small-neighborhood scale based on cost-benefit analysis. The study used benefit-cost analysis. Literature studies collect data from national and international journals, law products, and government policies. The study resulted that composting required more area than pyrolisis. It is a constraint criterion to consider applying the composting method in TPS 3R. The social cost green house gas (GHG) was the biggest component that contributed to the total cost. Meanwhile, in total benefit, the benefit sale of product solid waste treatment was the biggest. Pyrolisis was more feasible than composting based on BCR value. The composting duration was the limiting factor that affected the BCR value negatively (less than 1). It indicated to sustainable running, TPS 3R should be subsidized on investment and operational costs. Composting should be applied at the household level to achieve the maximal benefit. Sharing responsibilities between the household level and TPS 3R management about percentage of processing organic waste should be implemented. It could level out household participation in solid waste management.
SENSORY ANALYSIS OF STARCH GARUT UTILIZATION (MARANTHA ARUNDINACEA L.) AS SUBSTITUTION MATERIAL FOR WHEAT FLOUR IN MAKING PASTA
Authors: Sobari Enceng
Published: December 2023

The purpose of this study was to determine the effect of arrowroot starch substitution on pasta making. The benefit of this research is that it can determine the effect of arrowroot starch substitution in the panelist preference level in starch content. The formulations used are arrowroot starch P1 50% and flour 50%, P2 arrowroot starch 70% and wheat flour 30%, P3 arrowroot starch 100 and wheat flour 0%. The parameters observed were sensory test of color, aroma, taste, texture and starch content. Data processing of hedonic test uses kruskawalis test analysis and duncan follow-up test. Starch content test data were analyzed using Analysis of Variance (ANOVA) the use of arrowroot starch as a substitution material affected the aroma and texture. Starch levels have decreased due to processing. The best treatment in the hedonic test process of arrowroot paste processing was obtained by adding 50% starch formulation and 50% flour while in starch carbohydrate test was obtained by adding 100% starch and 0% flour.
EFFECT OF ADDITION OF PALM OIL EMPTY BUNCH ASH ON BIOGAS PRODUCTION FROM PALM OIL MILL EFFLUENT
Authors: Purwanto Clinton velly
Published: December 2023

Palm oil mill effluent (POME) and empty palm fruit bunches (EPFB) are the waste with the largest amount of capacity resulting from the processing of the palm oil industry. POME has a high organic content that can be used as a biogas producer. This study used POME, EFB and cow dung as ingredients to produce biogas using an anaerobic batch digester with a volume of 20 liters, where each experiment had a different material composition and the addition of a different concentration of tankos ash solution. The purpose of this study was to determine the appropriate concentration of mixing a solution of tankos ash, POME, and cow dung in an effort to increase biogas production. The results showed that from several experiments that had been carried out during 30 days of observation, the experiment that had the highest value of biogas production and methane gas revenue was the experiment with a composition of 5 liters of cow dung, 5 liters of POME and 10 liters of tankos ash solution (1:1:2) has a biogas production value of 58,646 ml and CH4 methane gas revenue of 70.1%. It was concluded that the addition of tankos ash solution can significantly increase the pH of the waste digester and can increase the amount of biogas production with a certain concentration
EFFECT OF BROMELIN ENZYME CONCENTRATION ON COCONUT OIL QUALITY (Cocos nucifera)
Authors: Supriyanto Supriyanto
Published: December 2023

The traditional coconut oil processing process has the disadvantage of a long extraction and heating process. The use of bromelin enzyme from pineapple can speed up the extraction process in coconut oil. The use of bromelin enzymes in addition to accelerating the extraction process can also improve the quality of the oil produced. The purpose of this study is to determine the effect of the concentration of natural bromelin enzymes that can produce good quality coconut oil. The experimental design used was a randomized design complete with treatment using natural bromelin enzyme in the oil extraction process. The enzyme concentrations used were 0%, 1%, and 1.5% later compared to conventional methods. The parameters in this study include yield, moisture content, specific gravity, viscosity and free fatty acids. The data from the study were analyzed using anova α 5% if there was an effect, further tests were carried out using DMRT α 5%.  The results of this study showed that different enzyme concentrations had a significant effect on the quality of coconut oil. The analysis results showed that A3 treatment (1.5% bromelin enzyme) was the best treatment compared to other treatments with a yield of 11.00±0.28; moisture content 0.05%±0.00, specific gravity 0.97±0.02; viscosity 0.78±0.02; and free fatty acid levels of .65±0.01%.
Implementation Analysis of Employee Job Descriptions as Supporting the Development of Pisang Umkm Segading Ponorogo
Authors: Agustin Agustin Rani Nurfadila , Negara Palmadi Putri Surya , Utomo Ilham Prasetyo
Published: December 2023

A job description is a division of work tasks for employees that aims to ensure that employees have responsibility for their respective jobs, which have been divided by their superiors. This research aims to encourage companies to consider the placement of human resources in their respective jobs. The method used is a survey and direct interviews with business owners using an open questionnaire to obtain data on the business. The data sources used are business owners, places or events, and employees at the Pisang Segading Ponorogo MSME business. Based on the research results, it can be concluded that the UMKM Pisang Segading Ponorogo has not implemented job descriptions properly for three employees, so employees still often work concurrently with eight working hours so that the impact of the product produced does not meet the production target of 25 kg, apart from that in the UMKM Pisang Segading Ponorogo also does not yet have an organizational structure so that employee placements are still not well structured. Efforts made to address these obstacles are by adding employees by threatening employees and employees at the Pisang Segading Ponorogo UMKM by providing job descriptions so that they will be more focused and productive in their respective jobs. So, the solution above can support the progress and curiosity of UMKM Pisang Segading Ponorogo.
Review of Parameters, Performance Models, And Applications of Biofiltration Technology In Reducing H2S Compounds In The Air
Authors: Sundari Utari Yolla , Qubra Tawaffani , Chiarawipa Rawee , Defri Ifwarisan
Published: December 2023

High-quality air is essential for human survival. The present-day has a negative effect on air quality. Air contamination from the harmful compound H2S is an important problem. The primary source of H2S discharges is the oil and gas industry, where it is a by-product of resource harvesting and processing. Further sources of H2S discharges into the atmosphere include mining, waste management, and fossil fuel burning. H2S generates a malodorous scent resembling that of decayed eggs, which can prompt respiratory discomfort and irritation in humans and animals. At elevated concentrations, it may induce toxicity and even fatalities. Biofiltration is one of the latest remarkable technological advances for mitigating this issue. This method employs microorganisms to convert H2S into less harmful compounds. Biofiltration offers the major benefit of low operational expenditure and minimal environmental impact. This paper contributes to our comprehension of the microbial parameters, designs, models, applications and processes that affect biofilter efficiency. Diffusion-based biofiltration models show greater efficacy in design systems. Furthermore, advances in media, including the use of hollow cylindrical particles, have increased the efficiency of biofiltration. Sulfur-oxidizing microorganisms, such as Thiobacillus sp., play a pivotal role in decreasing H2S compounds.  It is crucial to regularly monitor and regulate moisture levels, pH, temperature, and nutrient content to secure optimal and consistent biofiltration performance. The technology's effectiveness and stability heavily depend on precise control of these parameters. Biofiltration technology is hailed as a promising approach to manage H2S compounds, safeguard air quality, and preserve human health and the environment.
Assessment of Flood Susceptibility in the Cachar District of Assam Using Gis Based Multi-Criteria Decision Making and Analytical Hierarchy Process
Authors: Borah Preeti Barsha , Longkumer Lanusashi , Handique Arpana , Dutta Chandra Kumar , Bori Diram , Acharjee Shukla
Published: December 2023

Assam experiences significant floods every year, that causes damage to both people and infrastructure. By acquiring and analysing data which is required for hydrological research, geographic information systems and remote sensing technologies can assist to comprehensive flood management. A collection of 10 parameters, including elevation, slope, distance from the river, distance from road, drainage density, flow accumulation, land use and land cover, and Normalised Difference Vegetation Index derived from Landsat 8 OLI/TIRS images, the Environmental System Research Institute’s land cover and the Shuttle Radar topographic Mission’s Digital Elevation Model data from the United States Geological Survey have been used. The Barak basin of Assam's Cachar District was selected as our study area. After the selection of all the components, weights were assigned to each component through the Analytical Hierarchy Process. The influence value of the Topographic Wetness Index was assigned the highest weight in the final weighted overlay analysis that combined all the components. The output zones were divided into five flood prone zones as very low, low, moderate, high, and very high. The results show that 22.67% of the total area is characterized by high-flood zones, while extremely high flood-risk areas cover 0.01% of the area. The high flood-risk zones are densely populated. The Silchar town of Cachar falls under a very high-risk zone, with the highest population density. This work will help policymakers, planners, researchers and emergency responders with disaster preparedness and management.
Ex Vivo Validation of Magnetically Actuated Intravascular Untethered Robots in a Clinical Setting
Authors: Khalil Islam , Ligtenberg Leendert-Jan , Rabou Nicole , Goulas Constantinos , Duinmeijer Wytze C. , Halfwerk Frank R. , Arens Jutta , Lomme Roger , Magdanz Veronika , Klingner Anke , Rot Emily Klein , Nijland Colin H.E. , Wasserberg Dorothee , Jonkheijm Pascal , Liefers H. , Susarrey-Arce Arturo , Warle Michiel
Published: December 2023

Intravascular surgical instruments necessitate precise navigation within narrow vessels, requiring maximum flexibility, minimal diameter, and high degrees of freedom. However, existing tools often lack adequate control during insertion due to undesirable bending, which not only limits vessel accessibility but also poses a risk of tissue damage. The advancement of nextgeneration instruments aims to develop hemocompatible untethered devices that achieve precise control through external wireless forces and torques applied from outside the body. However, achieving this goal remains complex due to the challenges involved in testing and implementing untethered magnetic robots (UMRs) in clinical environments. These challenges encompass wireless actuation, non-invasive localization, biocompatibility, control robustness, and effective engagement. In this study, we assess the operational effectiveness of hemocompatible UMRs in clinical settings. We utilize an ex vivo porcine aorta model that accounts for factors such as varying blood-vessel diameters, varying blood flow rates, and the presence of renal aortic side-branches. This comprehensive approach enables us to analyze the robots’ motion dynamics within vessels, closely simulating real physiological and anatomical conditions. Our findings, in the absence of clotting, reveal a consistent linear reduction in UMR swimming speed against increasing arterial blood flow. Furthermore, our experiments showcase the UMR’s ability to generate sufficient force to navigate against a maximum arterial flow rate of 67 mL/min. Using the predicted and observed physical interactions of the UMRs, we effectively demonstrate preliminary proof-of-concept locomotion in a difficult-to-access target site, allowing us to navigate through the abdominal aorta and successfully reach the distal end of the renal artery.
Influence of rainfall pattern and infiltration capacity on the spatial and temporal inundation characteristics of urban waterlogging
Authors: Jiang Yishuo , Li Jiake , Li Yiping , Gao Jiayu , Xia Jun
Published: December 2023

The rapid development of the city leads to the continuous updating of the ratio of land use allocation, especially during the flood season, which will exacerbate the significant changes in the spatial and temporal patterns of urban flooding, increasing the difficulty of urban flood forecasting and early warning. In this study, the spatial and temporal evolution of flooding in a high-density urban area was analyzed based on the Mike Flood model, and the influence mechanisms of different rainfall peak locations and infiltration rate scenarios on the spatial and temporal characteristics of urban waterlogging were explored. The results revealed that under the same return period, the larger the rainfall peak coefficient, the larger the peak value of inundation volume and inundation area. When the rainfall peak coefficient is small, the higher the return period is, and the larger the peak lag time of the inundation volume is, in which P = 50a, r = 0.2, the delay time of the inundation volume for the inundation depths H > 0.03 m and H > 0.15 m reached 32 min and 45 min, respectively, At the same time, there are also significant differences in the peak lag time of waterlogging inundation volume in different inundation depths. The greater the inundation depth, the longer the peak lag time of waterlogging inundation volume, and the higher the return period, the more significant the effect of lag time prolongation. It is worth noting that the increase in infiltration rate will lead to the advance of the peak time of inundation volume and inundation area, and the peak time of the inundation area is overall more obvious than that of inundation volume. The peak times of inundation volume and inundation area were advanced by 4 ~ 8 min and − 2 ~ 9 min for H > 0.03 m and H > 0.15 m, respectively, after the increase in infiltration rate; and the higher the return period, the smaller the rainfall peak coefficient and the longer the advance time. The spatial and temporal characteristics of waterlogging under different peak rainfall locations and infiltration capacities obtained in this study can help provide a new perspective for temporal forecasting and warning of urban waterlogging.
Aberration-Corrected STEM to Determine the Surface Coverage and Distribution of Immobilized Molecular Complexes
Authors: Stach Eric , Jeon Sungho , Nedzbala Hannah , Huffman Brittany , Pearce Adam , Donley Carrie , Jia Xiaofan , Bein Gabriella , Choi Jihoon , Durand Nicolas , Atallah Hala , Castellano Felix , Dempsey Jillian , Mayer James , Hazari Nilay
Published: December 2023

The surface immobilization of molecular catalysts is attractive because it combines the benefits of homogeneous and heterogeneous catalysis. However, determining the surface coverage and the distribution of a molecular catalyst on a solid support is often challenging, inhibiting our ability to control catalytic performance. Here, we demonstrate that scanning transmission electron microscopy can image the location of the metal center in surface-attached transition metal complexes with atomic resolution. Using a machine learning model, we can analyze many images to determine surface coverage and distribution in a non-destructive manner. This allows us to establish how changes to the molecular catalyst affect surface coverage and distribution. Our work describes a new method to characterize surface-attached catalysts, which is likely general to many systems.
Spatial Variations in Porcine Liver Coefficient of Thermal Expansion
Authors: Mcghee Alexander , Evans Audrey , Hagness Susan , Ma Chu , Franck Christian
Published: December 2023

The coefficient of thermal expansion (CTE) of biological tissues is an important parameter in the application of many energy-based biomedical therapies. In this study, we employ 2D Digital Image Correlation (DIC) to monitor surface displacement and determine the corresponding strain in tissue samples subjected to temperature fluctuations in a water bath. By combining this data with recorded water temperature information, we create comprehensive maps of the CTE for porcine liver specimens. DIC provides a comprehensive analysis of the specimen's thermomechanical response, providing insight into the detailed strain behavior and structural characteristics of the tissue under investigation.
Reactivation of p53 as a radiosensitization strategy for mutant p53 cancers treated with high-LET radiotherapy
Authors: Cooks Tomer , Michaeli Or , Luz Ishai , Vatarescu Maayan , Weizmann Noam , Korotinsky Yevgeniya , Arazi Lior
Published: December 2023

Radiation therapy (RT) remains a common treatment for cancer patients worldwide, despite the development of targeted biological compounds and immunotherapeutic drugs. The challenge in RT lies in delivering a lethal dose to the cancerous site while sparing the surrounding healthy tissues. Low linear energy transfer (low-LET) and high linear energy transfer (high-LET) radiations have distinct effects on cells. High-LET radiation, such as alpha particles, induces clustered DNA double-strand breaks (DSBs), potentially inducing cell death more effectively. However, due to limited range, alpha-particle therapies have been restricted. In human cancer, mutations in TP53 (encoding for the p53 tumor suppressor) are the most common genetic alteration. It was previously reported that cells carrying wild-type p53 exhibit accelerated senescence and significant rates of apoptosis in response to RT, whereas cells harboring mutant p53 (mutp53) do not. This study investigated the combination of the high-LET RT based on 224Ra sources and APR-246 (a p53 reactivating compound) to treat tumors with mutant p53. Cellular models of colorectal cancer (CRC) or pancreatic ductal adenocarcinoma (PDAC) harboring mutant p53, were exposed to alpha particles, and tumor xenografts with mutant p53 were treated using Radium-224 (224Ra) source and APR-246. Effects on cell survival, tumor growth, and apoptosis were assessed. The spread of alpha emitters in tumors was also evaluated as well as the spatial distribution of apoptosis within the treated tumors. We show that mutant p53 cancer cells exhibit radio-sensitivity to alpha particles in vitro and to high-LET RT in vivo. APR-246 treatment enhanced sensitivity to high-LET radiation, leading to reduced tumor growth and increased rates of tumor eradication. Combining high-LET RT with p53 restoration via APR-246 triggered apoptosis, resulting in improved therapeutic outcomes. Further preclinical and clinical studies are needed to provide a promising approach for improving treatment outcomes in patients with mutant p53 tumors.
Evolving Perceptions of Climate Risk in the US Municipal Bond Market
Authors: Adriaens Peter , Li Dan , Saigal Romesh
Published: December 2023

The global water cycle has experienced significant changes due to the interplay of climate shifts and human activities, resulting in more frequent and severe droughts and floods. While municipal bonds serve as the primary financing method for public water agencies, the understanding of the impact of climate risks on the bond market remains limited. Analyzing a decade of water bond data (2009-2019), this study offers empirical evidence on the impact of flood and drought risks on municipal bond spreads, which serve as indicators of the additional yield bond investors demand to offset risks and, consequently, the financing costs for water agencies and municipalities. The results reveal that bond markets began factoring in flood risks in 2013, whereas drought risks exhibited a different trend before that year, closely tracking with the actual damage caused by flood and drought hazards. Using a structural credit risk model, we show the moderating effects of water sales and investor perceptions of climate change on climate risk pricing in the bond market. These findings have far-reaching implications for climate risk management and the sustainable stewardship of our water resources, as regions with heightened climate risk exposure are perceived as riskier by market participants, leading to a higher cost of capital.
Impact of functional capacity before hematopoietic stem cell transplantation on the length of hospital stay
Authors: Penna Giana Berleze , Silva Tassiana Costa da , Pedroni Anderson Sartor , Macagnan Fabricio Edler , Ziegler Bruna
Published: December 2023

Objective: To verify the association between pre-HSCT functional capacity and the variables of pulmonary function, fatigue and length of hospital stay.
Methods: This is a cohort study, involving patients admitted to the Bone Marrow Transplantation. The individuals were submitted to an evaluation in the first 24 hours of hospitalization. The length of stay variable was checked on the day of hospital discharge. Functional capacity was assessed through the 6MWT, the 30-second sit-to-stand test (TSL30) was performed to assess the indirect strength of the lower limbs, moreover was used Revised Piper Fatigue Scale and evaluation of the pulmonary function.
Results: The sample consisted of thirty-five individuals (19 male; 54%). Fourteen patients achieved a 6MWT ≥80% predicted. The mean age of the sample was 45.5 ± 15.2 years, and BMI 27.4 ± 5.4 kg/m². Patients who completed a 6MWD below the predicted value showed significantly lower pulmonary function values for the variables PEF(%) (p=0.031), FEV1 (%) (p=0.033) and FEV1/FVC(%) (p=0.027) in relation to the group with better functional capacity. This group showed significantly higher values in the assessment of lower limb fatigue using the Borg scale pre (p=0.008) and post (p=0.004) 6MWT, longer hospitalization time (p=0.0014), but with no significant difference in lower limb muscle strength between groups (p=0.21). A moderate correlation was found between the 6MWD% and FEV1% (p<0.05).
Conclusion: Data indicate that starting HSCT treatment with lower-than-expected physical fitness is associated with lower lung function, greater fatigue in the lower limbs, and longer hospital stays.
Plasma metabolomics signatures of developmental dysplasia of the hip in Tibet plateau
Authors: Guo Ye , li Xiaogang , yang De , Yedron Nyima , Chen Tao , Li Jianchu , Lei Yanming , Li Ping , Ji Jiamei , Shi Li , Cho Ten , Yang Xiao
Published: December 2023

Background: Developmental dysplasia of the hip (DDH) is a common childhood health complaint, whose etiology is multifactorial. The incidence of DDH is variable and higher in Tibet plateau. Here, we collected plasma samples and studied the metabolomics signatures of DDH.
Methods: Fifty babies were enrolled: 25 with DDH and 25 age-matched non-DDH healthy controls(HC group). We collected plasma samples, laboratory parameters and conducted untargeted metabolomics profiling.
Results: There are many differential metabolites among patients with DDH, including 4-β-hydroxymethyl-4-α-methyl-5-α-cholest-7-en-3-beta-ol, β-cryptoxanthin, α-tocopherol, taurocholic acid, glycocholic acid, 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate, arabinosylhypoxanthine, leucyl-hydroxyproline, hypoxanthine. The main differential metabolic pathways focused on primary bile acid biosynthesis, arginine and proline metabolism, phenylalanine metabolism, histidine metabolism, purine metabolism.
Conclusions: To our knowledge, this is the first report of metabolomics profile in babies with DHH. By combining the α-tocopherol and taurocholic acid, we could achieve the differential diagnosis of DDH.