bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementasi Model Pembelajaran Berbasis Masalah Dalam Pembelajaran Pendidikan Jasmani Secara Daring
Authors: Khan Latif , Chaerul Andrie , Resita Citra
Published: November 2022

Latar belakang penelitian ini adalah kurangnya keaktifan siswa dalam proses pembelajaran pendidikan jasmani secara daring. Diperlukan sebuah usaha untuk meningkatkan keaktifan siswa, dengan upaya guru melalui penerapan model pembelajaran berbasis masalah secara daring. Penerapan model pembelajaran berbasis masalah secara daring digunakan oleh peneliti sebagai solusi dalam meningkatkan keaktifan siswa dalam proses pembelajaran pendidikan jasmani, hal ini sejalan untuk mencapai tuntutan Kurikulum di Indonesia yang sudah menggunakan Kurikulum 2013 yaitu siswa dituntut aktif pada saat proses pembelajaran dilakukan. Penelitian ini bertujuan untuk mengetahui bagaimana implementasi model pembelajaran berbasis masalah dalam pembelajaran pendidikan jasmani secara daring di SMK Al Fathimiyah. Penelitian ini menggunakan metode kualitatif. Penelitian ini dilakukan pada bulan Juli hingga Agustus 2022. Lokasi penelitian dilakukan di SMK Al Fathimiyah Karawang, dengan subjek penelitian 1 orang guru PJOK dan 6 siswa kelas 11. Pengumpulan data menggunakan teknik observasi dan wawancara. Data disajikan secara deskriptif. Hasil penelitian ini menunjukkan bahwa model pembelajaran berbasis masalah sudah efektif dilakukan pada saat proses pembelajaran pendidikan jasmani secara daring di SMK Al Fathimiyah, dan pelaksanaan model pembelajaran berbasis masalah dapat dipahami dan dilakukan dengan baik di SMK Al Fathimiyah Karawang.
Model Scramble Untuk Meningkatkan Kemampuan Membaca Pemahaman Siswa
Authors: Putri Anggitasari Rudyana , Ardianti Sekar Dwi , Ermawati Diana
Published: November 2022

Penelitian ini dilatarbelakangi dengan temuan permasalahan kemampuan membaca pemahaman yang rendah pada siswa. Hal tersebut terjadi kerena proses pembelajaran dilakukan secara konvensional belum menggunakan model pembelajaran yang sesuai untuk meningkatkan kemampuan membaca pemahaman. Penelitian ini bertujuan untuk mengetahui perbedaan dan peningkatan kemampuan membaca pemahaman siswa menggunakan model pembelajaran scramble. Metode penelitian yang digunakan yaitu kuantitatif pre-eksperimental dengan jenis one-group pretest-posttest. Pelaksanan penelitian dilakukan pada bulan Mei 2022 di SD 4 Karangbener. Jumlah sampel terdiri dari 24 siswa. Instrumen penelitian menggunakan teknik tes dan non tes. Teknik tes menggunakan soal pretest dan posttest, sedangkan teknik non tes menggunakan observasi, wawancara dan dokumentasi. Adapun hasil penelitian menunjukan model scramble berpengaruh untuk meningkatkan kemampuan membaca pemahaman bagi siswa kelas III di SD 4 Karangbener. Sehingga, dapat disimpulkan bahwa penggunaan model scramble berpengaruh untuk meningkatkan kemampuan membaca pemahaman siswa.
Analisis Survei Terhadap Pengguna Grammarly
Authors: Marliyanda Aisna , Wachyudi Kelik , Kartini Dedeh
Published: November 2022

Latarbelakang penelitian ini adalah penulis ingin meneliti penggunaan kecerdasan buatan yakni Grammarly dalam pendidikan bahasa Inggris. Tujuan penelitian ini adalah untuk mengetahui persepsi dari partisipan terkait penggunaan alat grammarly selama penulisan skripsi berbahasa Inggris yang telah mereka lakukan. Metode yang digunakan dalam penelitian ini adalah metode deskriptif survey.  Penulis menggunakan instrumen angket untuk mengetahui persepsi teman sejawat dalam menggunakan grammarly selama proses menulis skripsi berbahasa Inggris yang telah mereka lakukan. Penelitian ini dilakukan pada tahun 2022 dan peneliti telah melakukannya disalahsatu universitas di Karawang. Penulis telah mengambil lima partisipan dan dilakukan di Karawang.  Hasil dan pembahasan dalam penelitian ini menunjukkan bahwa partisipan sangat terbantu selama proses mengerjakan skripsi berbahasa Inggris. Secara umum mereka lebih percaya diri dan berminat untuk tetap menggunakan grammarly pada saat dan sesudah kuliah. Akses grammarly yang sangat mudah baik secara mudah telah membuat mereka berpadangan positif terhadap alat ini. Simpulan dalam penelitian ini, grammarly sebagai alat asistensi umpan balik tatabahasa secara otomatis ini sangat membantu para partisipan dalam menulis skripsi bahasa Inggris.
Dampak Penggunaan Gadget Terhadap Perkembangan Karakter Siswa Sekolah Dasar
Authors: Sauri Sopian , Sulastri Andi , Hakim Arif Rahman , Sururuddin Muhammad
Published: November 2022

Penelitian ini bertujuan untuk mengetahui dampak penggunaan gadget terhadap perkembangan karakter siswa sekolah dasar yang ada di dusun limbungan. Untuk mengetahui dampak positif dan negatif gadget terhadap perkembangan karakter siswa SD di dusun limbungan. Jenis penelitian ini menggunakan Deskriptif kualitatif, sedangkan pengumpulan data menggunakan adalah wawancara, observasi dan dokumentasi secara langsung dengan informan yang ada dilapangan untuk mendapatkan data yang dibutuhkan. Analisis data menggunakan teknik analisis data Miles dan Huberman yaitu Pengumpulan data, Reduksi data, Penyajian data, dan penarikan kesimpulan atau verifikasi untuk mengetahui dampak penggunaan gadget terhadap perkembangan karakter siswa sekolah dasar Dusun Limbungan. Hasil penelitian ini menunjukkan bahwa terdapat beberapa dampak penggunaan gadget terhadap perkembangan karakter siswa sekolah dasar di Dusun Limbungan, diantaranya siswa menjadi seorang yang individualis, jarang melakukan interaksi sosial dengan lingkungan luar atau teman sebayanya, lalai terhadap kewajibannya seperti belajar, tidak memperdulikan apapaun sampai melupakan waktu seperti melalaikan  solat, dan bermalas-malasan untuk mengaji hal ini sangat mempengaruhi sikap sosial, tanggung jawab dan sikap religius siswa. Dampak tersebut disebabkan siswa yang terlalu sering menggunakan gadget dengan durasi waktu yang terlalu lama dan kurangnya pengawasan dari orang tua yang membuat siswa menajdi kecanduan dan membuat siswa menjadi malas melakukan hal yang lebih bermanfaat.
TES POWER OTOT LENGAN, KETEPATAN SERVIS DAN PENERAPAN LATIHAN SERVIS TOP SPIN BOLAVOLI
Authors: Kuncoro Bagus , Budiyono Kodrad , Agus TW Risa
Published: November 2022

Pembinaan prestasi atlet bolavoli dapat dimulai sejak anak usia dini. Banyak ahli dan praktisi diwilayah kabupaten Sragen mendirikan klub bolavoli usia dini, salah satunya klub popsi Sragen yang melatih atlet mulai umur 10-12 tahun. Dalam pengabdian masyarakat ini, berlangsung pada 6 oktober 2020 sampai 7 september 2020 dihadiri 30 peserta, 2 pelatih dan 1 asisten pelatih popsi Sragen. Kegitan berupa penyampaian materi dan praktek langsung implementasi model latihan servis top spin, pengukuran power otot lengan dan tes evaluasi servis top spin. Dalam menghasilkan kemampuan kondisi fisik dan teknik yang maksimal melalui servis top spin, peserta dibagi dalam beberapa tahapan yang mengarah pada pelatih dan atlet servis top spin. Hasil praktek setiap sesi pertemuan dilakukan pendampingan evaluasi metode latihan serta tes evaluasi secara terstruktur. Dari hasil evaluasi diperoleh hasil dan manfaat dari kegiatan pengabdian ini diantaranya: (1) pelatih dan asisten pelatih mampu memahami teknik servis top spin bolavoli, dan pembuatan teknik, strategi, kondisi fisik serta program latihan yang sesuai, (2) Atlet Klub popsi Sragen usia dini umur 10-12 tahun dapat diketahui power otot lengan dan kemampuan ketepatan servis top spin.
The Trouble with Relational Values
Authors: Luque-Lora Rogelio
Published: November 2022

This paper questions the conceptual and pragmatic worth of the category of relational values. Combining philosophical reasoning with ethnographic field-work in Wallmapu/Chile, I analyse a variety of ways in which people think about, value and behave toward the land. I thereby demonstrate that relational-ity is inherent to held, instrumental and intrinsic values. This means that there is no meaningful way in which to distinguish relational values from more familiar types of values. Yet, to be able to argue that a distinct class of relational values exists, those who have proposed the term have been compelled to silence or downplay the relational natures of those other values. This has the perverse effect of confining, rather than promoting, relational thinking.
Ortaöğretim coğrafya ders kitaplarında tematik harita kullanımının incelenmesi
Authors: ŞAHİN Bahaddin , BOZYİĞİT Recep
Published: November 2022

İçinde yaşadığımız büyük veri çağında daha önce hiç olmadığı kadar büyük miktarda veri üretilmekte ve paylaşılmaktadır. Üretilen ve paylaşılan mekânsal veriler arttıkça tematik haritaların da önemi artmaktadır. Bu durumun temel nedeni herhangi bir verinin dağılışının oluşturduğu mekânsal örüntüyü en iyi yansıtabilecek görselleştirme aracının tematik haritalar oluşudur. Nitel ve nicel verileri haritalamak için farklı tematik haritalama yöntemleri kullanılmaktadır. Bu haritalama yöntemlerinin her birinin avantajlı ve dezavantajlı yönlerinin neler olduğu, hangi tip verilerin gösteriminde hangi tematik haritalama yöntemlerinin kullanılabileceği gibi temel kartografik becerilerin harita okuyucusu tarafından kazanılması son derece önemlidir. Bu becerilerin kazanılmasında ise ders kitapları büyük öneme sahiptir. Bu araştırmanın amacı ortaöğretim coğrafya ders kitaplarında yer alan tematik haritaların; ünitelere, haritalama yöntemlerine ve nitel/nicel veri durumuna göre dağılımı incelemektir. Araştırmada nitel araştırma yaklaşımları arasında yer alan doküman inceleme tercih edilmiştir. Araştırmanın veri kaynağını 2021-2022 eğitim-öğretim yılında 9, 10, 11 ve 12.sınıf seviyelerinde okutulan ortaöğretim coğrafya ders kitapları oluşturmaktadır. Eğitim Bilişim Ağı (EBA) üzerinden ulaşılan ders kitapları, araştırma için geliştirilen veri inceleme formu aracılığıyla betimsel içerik analizi kullanılarak incelenmiştir. Araştırma sonucunda ders kitaplarının yer alan tematik haritaların; ünitelere göre dağılımın son derece düzensiz olduğu, tematik haritaların büyük ölçüde korogromatik ve nokta sembol yöntemini içeren haritalardan oluştuğu ve nitel tematik harita sayısının nicel tematik haritalara göre oldukça az olduğu saptanmıştır.
Effects of Machining Parameters on Feed Direction Cutting Forces in Meso-Scale End-Milling of Ti-6Al-4V Under Dry, Wet and MQL Environment
Authors: Rauf Adil , Jaffery Syed Husain Imran , Khan Mushtaq , ul-Qadir Najam , Ahmed Shamraiz , Zahid Danyal
Published: November 2022

High strength, resistance to corrosion, small density and remarkable strength to weight ratio of titanium distinguish it from other metals and is a reason for its use in in renowned industrial setups like bio-medical, automotive, aeronautics, and power generation industries. However, these are considered as difficult-to-machine elements because of less heat conductivity, minimum value of modulus of elasticity, substantial chemical reactivity and elevated temperature strength. Ti-6Al-4V is regarded as major industrial alloy and a focus of research studies. Measurement and analysis of machining forces provides a deep insight into the mechanics of machining and assist in understanding machinability, tool wear / fracture, machining precision, chatter stability, energy, surface quality and temperature. This further helps in finding optimum machinability parameters for different materials. Machining forces are affected by a number of factors including cutting conditions and lubrication / cooling environment. In this research, analysis of milling forces under three different lubrication / cooling environments i.e. Dry, Wet and MQL (Minimum Quantity Lubrication) along with effects of milling parameters during meso-scale milling of Ti-6Al-4V has been conducted. End milling experiments have been performed basing on Taguchi L9 orthogonal array for optimal combination of milling parameters, keeping spindle speed, depth of cut, feed per tooth and cooling conditions as the control factors. Contribution ratios of different milling parameters and lubrication / cooling environment on feed direction forces have been analyzed through ANOVA.
The Dual Role of Astrocyte-Derived Exosomes and Their Contents in the Process of Alzheimer’s Disease
Authors: Liu Ziyu , Zhang Haotian , Liu Shiji , Hou Yi , Chi Guangfan
Published: November 2022

Millions of patients worldwide are affected by Alzheimer’s disease (AD), and the number of patients with AD is increasing. However, current treatment can only improve symptoms but cannot cure the disease. Astrocytes, glial cells in the central nervous system, play important roles in support, nutrition, protection, and information transmission in the nervous system. Pathological changes in astrocytes are closely associated with the development and progression of AD. As carriers for material and information exchange between astrocytes and other neural cells, astrocyte-derived exosomes (ADEs) have been widely studied in recent years, and ADE secretion has been shown to be increased in patients with AD and animal models of AD. ADEs contain a variety of substances, including nucleic acids, proteins, and lipids. The contents of ADEs can effectively control oxidative stress and detoxification during the early development of AD, thereby playing positive and negative roles in the occurrence and development of AD. In this review, we elaborate on the functions of ADEs and their components in AD and discuss their applications in AD research and clinical practice.
Deficiency of vitamins and micronutrients and reproductive health in women
Authors:   Novosibirsk State University, Novosibirsk, Russian Federation, Kudinova E.G.
Published: November 2022

Aim: to identify the content of vitamins and micronutrients in the blood of young female patients. Patients and Methods: a prospective single-center study included young female patients aged 18–24 years with complaints of menstrual disorders (MD) or manifestations of androgen-dependent dermopathy (acne, seborrhea, alopecia). Clinical, anamnestic and anthropometric parameters, hormonal profile involved in the realization of reproductive function, a number of biochemical blood parameters, and pelvic ultrasound data were evaluated. Results: the study included 133 female patients divided into 4 groups. Group 1 (n=53) consisted of female patients with MD, group 2 (n=44) — women with manifestations of hyperandrogenism (HA; acne and post-acne, alopecia, seborrhea) and MD, group 3 (n=9) — female patients with HA manifestations without MD, group 4 (n=27) — female patients without HA and MD (conditionally healthy). 41% of female patients of the 1st and 2nd groups and 44% of the 3rd group showed signs of an increase in the ovarian volume and changes in their structure (multifollicular or polycystic ovaries). Echographic signs of anovulation were detected in 26.1, 32.3 and 35.0% of female patients in groups 1, 2 and 3, respectively. Comparison of the androgenic steroid level in the groups did not reveal statistically significant differences, however, there were borderline cortisol levels and higher values of plasma 17-OH progesterone (vs the group 1) in groups 2 and 3. Values of gonadotropins did not differ significantly, but the LH/FSH ratio was higher in group 2, although unreliable. Hyperprolactinemia was detected in every fourth female patient of groups 1, 2, 3 (value range from 737 to 1079 mIU/L). 25(OH)D content was reduced in all three groups, amounting to 16.4±8.4, 24.7±13.2 and 11.4±4.5 ng/mL, respectively. Although homocysteine levels were borderline (11.5±2.9, 9.7±2.8 and 9.4±2.7 μmol/L), they differed statistically significantly (p<0.0002) in the groups. Besides, borderline low levels of folic acid, vitamin B12 and serum ferritin were found in groups 1, 2 and 3. Conclusion: the disorders detected in women with MD and HA should be taken into account when forming the treatment tactics. KEYWORDS: menstrual disorders, hyperandrogenism, homocysteine, ferritin, vitamin D, B vitamins. FOR CITATION: Kudinova E.G. Deficiency of vitamins and micronutrients and reproductive health in women. Russian Journal of Woman and Child Health. 2022;5(3):182–187 (in Russ.). DOI: 10.32364/2618-8430-2022-5-3-182-187.
Optimizing surgical management of uterine cervix disorders
Authors:   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Il’ina I.Yu. , Dobrokhotova Yu.E. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: November 2022

Aim: to improve outcomes of the surgical management of cervix disorders by using a hemostatic agent with antimicrobial activity. Patients and Methods: the study included 47 women, 25–45 years of age, with CIN II/III to whom cervical radiofrequency ablation was performed. The main group comprised 26 (55.3%) patients. During the ablation procedure, a 1% aqueous solution of incomplete polyacrylic acid silver salt with integrated nanoparticles was used as an additional treatment for this group of patients. The control group consisted of 21 (44.7%) patients for whom the standard ablation technique was used. The assessed criteria included the clinical course and laboratory test results before and three months after the surgical treatment, as well as the bleeding rates. Results: in the main group of patients, the mean leucocyte number in the smear after the treatment was 9.2±1.2 per field of vision, in the control group — 18.5±2.9; pH of the vaginal discharge — 4.2±0.2 (from 3.8 to 4.5) and 4.7±0.2 (from 4.2 to 5.8), respectively. Intraoperative bleeding from the surgical wound which required additional manipulations was reported in 2 (7.7%) patients of the main group and 2 (9.5%) patients of the control group. Ten days after the surgery, one patient (3.8%) from the main group had complaints on heavy bloody vaginal discharge. Three (14,3%) patients from the control group had the same complaint 11–13 days after the surgery (3.7 relative risk, 95% confidence interval (CI) 1,0–18,2) which required the use of tranexamic acid as tablets for oral administration. Three months after the surgery the clue cells were found in one (3.8%) patient of the main group and in 7 (33.3%) patients of the control group (8.7 relative risk, 95% CI 1.2–16.5), and the fungal mycelia — only in 8 (38.1%) patients of the control group. Conclusion: the use of a 1% aqueous solution of incomplete polyacrylic acid silver salt with integrated nanoparticles during the cervical ablation resulted in a statistically significant reduction of the bleeding risk and improved the vaginal microflora profile in postoperative period. KEYWORDS: cervical dysplasia, cervical excision, cervical conization, bacterial vaginosis, hemostatic agent, bleeding. FOR CITATION: Il’ina I.Yu., Dobrokhotova Yu.E. Optimizing surgical management of uterine cervix disorders. Russian Journal of Woman and Child Health. 2022;5(3):188–193 (in Russ.). DOI: 10.32364/2618-8430-2022-5-3-188-193.
Characteristics of the pelvic organ dysfunctions in patients before and after genital prolapse surgery
Authors:   Ivanovo State Medical Academy, Ivanovo, Russian Federation, Smirnova A.V. ,   V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ivanovo, Russian Federation, Malyshkina A.I. ,   Ivanovo State Medical Academy, Ivanovo, Russian Federation,   V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ivanovo, Russian Federation, Kolganova I.A. ,   V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ivanovo, Russian Federatio, Shekhlova N.V. ,   V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ivanovo, Russian Federation, Abdullaeva Z.S. ,   V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ivanovo, Russian Federation
Published: November 2022

Background: descent of pelvic organs (genital prolapse, GP) of different severity is a significant medical and social problem. The key clinical manifestations in patients with GP comprise the impairment of pelvic organ functions which seriously affects the social adaptation of such patients. Aim: to assess specific clinical characteristics of the functional disorders of pelvic organs in patients with GP admitted for surgical treatment and to review changes in symptoms over time after surgery. Patients and Methods: a non-randomized prospective cohort study was carried out. The study group included 40 patients with different forms of GP, Grades II-IV under POP-Q classification system. All patients were interviewed before and 6 months after the surgical treatment using a new short version of PFDI-20 Questionnaire. Results: urinations disorders with a duration shorter than one year were reported in 19 (47%) women, from 1 year to 5 years — in 13(32,5%), from 5 to 10 years — in 1 (2,5%), and in 4 (10%) women the symptoms lasted for more than 10 years. It was found that 12(30%) of the interviewed women suffered from constipation, and 11 (27.5%) of patients had the feeling of incomplete defecation. Twelve (30%) patients complained of fecal and flatus incontinence. Six months after the operation, 7 (17.5%) patients mentioned some pain and discomfort in the lower abdomen. Urination disorders (urine dribble and incontinence, urethrodynia). Flatus incontinence remained in 3 (7.5) of the studied patients.
New treatment options for iron deficiency in women of different ages
Authors:   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Dobrokhotova Yu.E. , Markova E.A. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: November 2022

Nowadays, iron-deficiency anemia (IDA) in pregnant and perimenopausal women has become an important social and healthcare problem. Despite the implementation of various projects and the availability of multiple clinical guidelines on early anemia diagnosis and prevention, no significant reduction in the global prevalence of IDA is observed. The article discusses the clinical efficacy of a new combination drug, containing ferrous sulfate and folic acid which is used for the treatment of iron deficiency during pregnancy, and the assessment of ferrous sulfate efficacy in perimenopausal women. The article presents a review of literature sources published in the last five years which describe the trials of sustained-release bivalent iron formulations with and without folic acid. The drugs were administered to women with gynecologic diseases that caused a chronic iron loss during menopause and to patients with iron deficiency during pregnancy. The authors discuss the most important findings of the clinical trials assessing sustained-release bivalent iron formulation and its combination with folic acid which were used for treating pregnant women and gynecological patients of different ages. The literature data demonstrate that the combination drug, containing ferrous sulfate and folic acid is characterized by high clinical efficacy in the studied female populations with IDA. KEYWORDS: sideropenia, iron deficiency, iron-deficiency anemia, pregnancy, bivalent iron, folic acid, menopause, perimenopause, gynecological diseases. FOR CITATION: Dobrokhotova Yu.E., Markova E.A. New treatment options for iron deficiency in women of different ages. Russian Journal of Woman and Child Health. 2022;5(3):201–208 (in Russ.). DOI: 10.32364/2618-8430-2022-5-3-201-208.
Some aspects of precocious puberty in preschool-age girls
Authors:   Rostov State Medical University, Rostov-on-Don, Russian Federation, Chebotareva Yu.Yu. , Petrov Yu.A. ,   Rostov State Medical University, Rostov-on-Don, Russian Federation, Rodina M.A. ,   Medical Center Sem’ya, Rostov-on-Don, Russian Federation
Published: November 2022

Precocious puberty (PP) remains a challenging issue for pediatrics, particularly pediatric endocrinology, gynecology, and neurology due to its clinical and pathogenetic heterogeneity. And PP-associated psychosocial development of the girls also plays an important role. The article presents three case studies of pre-school age girls with precocious puberty amid organic brain syndrome, McCune-Albright syndrome, and pituitary cyst. In all cases thelarche was the main reason for contacting the doctor. The patient with organic brain syndrome had such a specific clinical feature as overweight and the patient with McCune-Albright syndrome — café-au-lait skin spots on the face, buttocks, and the left hand. These case studies demonstrate that for identifying girls with PP a multidisciplinary approach is needed. It will enable to examine a patient properly, make the correct diagnosis as early as possible, detect potential comorbidities and prescribe effective treatment, as well as to provide follow-up care including the assessment of physical and sexual development. Also, it is required to analyze hormonal profile and to perform pelvic ultrasound examination. The relationship between genetic and epigenetic factors in the development of these pathological conditions is discussed. KEYWORDS: precocious puberty, girls, thelarche, adrenarche, pituitary-hypothalamic-ovarian axis, epiphyseal tumor. FOR CITATION: Chebotareva Yu.Yu., Petrov Yu.A., Rodina M.A. Some aspects of precocious puberty in preschool-age girls. Russian Journal of Woman and Child Health. 2022;5(3):215–222 (in Russ.). DOI: 10.32364/2618-8430-2022-5-3-215-222.
Fermented milk-based baby drinks fortified by prebiotics and probiotics: impact on the health of infants and young children
Authors:   Russian Medical Academyof Continuous Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russian Federation, Zakharova I.N. ,   Z.A. Bashlyaeva Children’s City Clinical Hospital, Moscow, Russian Federation, Berezhnaya I.V. ,   Russian Medical Academyof Continuous Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russian Federation,   Z.A. Bashlyaeva Children’s City Clinical Hospital, Moscow, Russian Federation, Skorobogatova E.V. ,   Z.A. Bashlyaeva Children’s City Clinical Hospital, Moscow, Russian Federation
Published: November 2022

Nowadays, rational, balanced nutrition and fortified foods are becoming increasingly popular among physicians of different specialties who have medical practice settings throughout the world. Even earlier, these food shave been recommended for the prevention of multiple disorders, including such socially significant diseases as myocardial infarction, diabetes mellitus, obesity, cancer, and allergy. Trends of the past few decades have demonstrated that functional nutrition will provide most benefits if it is started from early childhood. As elsewhere in the world, novel probiotics are regularly developed in Russia as targeted therapies. The use of fermented milk-based products fortified by probiotics like S. Thermophilus FD DVS nutrish® La-5® (Lactobacillus acidophilus), Bifidobacterium animalis subsp. lactis ВВ-12 in baby formulae helps to achieve a balanced diet, develop positive nutritional behavior and to reduce the rate and severity of infectious and allergic diseases in children. The National program for optimizing nutrition of children in the Russian Federation serves as guide for doctors and parents allowing them to select the best products available on the market of commercially produced foods for infants and children. The article provides a definition of functional nutrition and characteristics of fermented foods in children’s diet. It also describes effects of various probiotic strains in the line of functional baby food. KEYWORDS: probiotics, S. Thermophilus, Lactobacillus acidophilus, functional baby food, fermented milk products for complementary feeding, biolact. FOR CITATION: Zakharova I.N., Berezhnaya I.V., Skorobogatova E.V. Fermented milk-based baby drinks fortified by prebiotics and probiotics: impact on the health of infants and young children. Russian Journal of Woman and Child Health. 2022;5(3):253–261 (in Russ.). DOI: 10.32364/2618-8430-2022-5-3-253-261.
Hemophagocytic lymphohistiocytosis associated with herpes infection
Authors:   Novosibirsk State Medical University, Novosibirsk, Russian Federation, Karpovich G.S. ,   Children’s City Clinical Hospital No. 3, Novosibirsk, Russian Federation, Shestakov A.E. ,   Novosibirsk State Medical University, Novosibirsk, Russian Federation, Krasnova E.I. ,   Novosibirsk State Medical University, Novosibirsk, Russian Federation
Published: November 2022

Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal disease affecting multiple organs and systems which is induced by the dysregulation of the immune response due to mutations in the genes controlling cytolytic function. This leads to the abnormal activation of cytotoxic T cells, monocytes/macrophages, and the development of a systemic inflammatory response. In some cases, patients with HLH require emergency therapy in intensive care or resuscitation units. The article highlights the issues of HLH etiopathogenesis, its clinical, diagnostic and treatment aspects. As association was found between secondary HLH and infections caused by the herpesvirus group. The diagnosis of this condition is challenging because of its nonspecific symptoms, especially in early stages of the disease, which leads to an uncertain prognosis. The authors present case reports of two pediatric patients with secondary HLH induced by herpesvirus mixed infection. The clinical cases were characterized by the manifestations of acute dual infection with Epstein-Barr virus and cytomegalovirus, and HLH symptoms that were consistent with the diagnostic criteria of the disease described in the article. For selecting an adequate therapy, it is necessary to conduct high-quality comprehensive diagnostic testing with the involvement of hematologists, rheumatologists. and oncologists. KEYWORDS: hemophagocytic lymphohistiocytosis, infectious diseases, herpes virus, Epstein-Barr virus, cytomegalovirus, hematology, mixed infection. FOR CITATION: Karpovich G.S., Shestakov A.E., Krasnova E.I. Hemophagocytic lymphohistiocytosis associated with herpes infection. Russian Journal of Woman and Child Health. 2022;5(3):262–269 (in Russ.). DOI: 10.32364/2618-8430-2022-5-3-262-269.
Lysosomal acid lipase deficiency: analysis of enzyme replacement therapy
Authors:   Omsk State Medical University, Omsk, Russian Federation, Polyanskaya N.A. , Gorbunova A.A. ,   Regional Children’s Clinical Hospital, Omsk, Russian Federation, Pavlinova E.B ,   Omsk State Medical University, Omsk, Russian Federation, Savchenko O.A. ,   Omsk State Medical University, Omsk, Russian Federation, Kirshina I.A. ,   Omsk State Medical University, Omsk, Russian Federation, Bagaeva M.E. ,   Federal Research Center for Nutrition and Biotechnology, Moscow, Russian Federation,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Strokova T.V. ,   Federal Research Center for Nutrition and Biotechnology, Moscow, Russian Federation,   Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: November 2022

Aim: to present the treatment results and the trend of clinical and biochemical parameters in two patients with lysosomal acid lipase deficiency (LALD) during enzyme replacement therapy (ERT). The reasons for the in-depth study of patients were the periorbital "shadows of intoxication" (hyperpigmentation), an increase in the liver and spleen sizes, revealed during medical examination, as well as the long-term subfebrility. Nonspecific clinical disease manifestations required an extended diagnostic search. LALD diagnosis, confirmed by the molecular genetic study results, was made at the age of 7 and 12 years. In both clinical cases, the prescription of pathogenetically based therapy provided positive trend in the form of improvement in physical development, reduction in the liver and spleen sizes, and persistent relief of hepatic cytolysis. The article considers the difficulties that a medical practitioner may face when monitoring patients with LALD receiving pathogenetic therapy. Special attention is paid to the possible causes of insufficiently effective reduction of cholesterol levels during ERT. The article also notes the importance of timely diagnosis of LALD, characterized by continuous pathological storage of cholesteryl esters in lysosomes, which is associated with the risk of irreversible lesions of organs and tissues. KEYWORDS: children, Lysosomal acid lipase deficiency, cholesteryl ester storage disease, dyslipidemia, cytolysis, sebelipase alfa, enzyme replacement therapy. FOR CITATION: Polyanskaya N.A., Gorbunova A.A., Pavlinova E.B. et al. Lysosomal acid lipase deficiency: analysis of enzyme replacement therapy. Russian Journal of Woman and Child Health. 2022;5(3):270–276 (in Russ.). DOI: 10.32364/2618-8430-2022-5-3-270-276.
Control of Sexually Transmitted Diseases in the Japanese Army in the Early 20th Century: Focusing on the Analysis of Venereal Disease by the Army
Authors:   The Korean Association for the Social History of Medicine, Yoo Ji-A
Published: November 2022

This study examines how prevalent an effect sexually transmitted diseases in modern times had on the Japanese army and how the Japanese government tried to manage them. After the Meiji Restoration, sexually transmitted diseases in the Japanese army, which had waged war every ten years, was viewed as a serious problem in connection with the decline in military power. The Meiji government, which had pursued a national policy of being prosperous and strong, analyzed that the reason for the continued decrease in the number of soldiers who were exempted from and evaded military service. However, as war broke out, the problem of the number of soldiers became bigger in infectious diseases and sexually transmitted diseases of soldiers. Therefore, the Ministry of the Army analyzed the effects of sexually transmitted diseases on the military by investigating the trend of sexually transmitted diseases. According to a survey conducted by the Ministry of the Army at the time, sexually transmitted diseases in the Japanese army accounted for 46.40‰ of the total number of soldiers, and the number of people exempted from military service and discharged due to sexually transmitted diseases reached 7‰. Therefore, in the process of establishing the emergency law in 1908, the Ministry of the Army considered sexually transmitted diseases as major infectious diseases and accurately investigated the types of sexually transmitted diseases, the causes of infection, and the treatment process. And the Japanese Ministry of Army strictly forbade the use of brothels to prevent sexually transmitted diseases. At the same time, strict mental training and condom use were encouraged. Despite these efforts of the army, the problem of sexually transmitted diseases in the army has not been solved. Afterwards, the Japanese Army installed comfort facilities in the expeditionary war that led to the deployment to Siberia and the Manchurian Incident to manage sexually transmitted diseases among soldiers.
The Formation of Autonomous Organizations for Patients with Hansen’s Disease at Aeyangwon(愛養園) and Changes in the Characteristics of the Patient Community
Authors:   The Korean Association for the Social History of Medicine, Jang Min Han , Yu Yon-Sil
Published: November 2022

This paper focuses on the operation of autonomous organizations for patients at Aeyangwon(愛養園) to analyze the following two aspects. First, it studies the relationship between autonomous organizations and church power at Aeyangwon in different periods, and examines the changes in the characteristics of its patient community. Aeyangwon experienced several historical changes: Guangzhu Na(癩) Sanatorium Period (1910-1926), Yeosu Aeyangwon Period (1926-1934), and the Ilsimhoe(一心會) Incident and the Movement Period to force Pastor Kim Eung-gyu to step down (1934-1940). Its characteristics also changed from a “missionary-centered belief community” to a “patient-centered life community.” The characteristics of the patient community had changed according to the relationship between operation leadership (hospital and church) and autonomous organizations for patients. The autonomous organization at Guangzhu Na(癩) Sanatorium functioned under the leadership of missionaries, and the patient leader was also appointed by the president of the hospital; thus, the patients could not enjoy much independence. From 1926 to 1934, as the autonomous organization grew with Executive Committees at its center, opposition between the church power and the patients also occurred. This was manifested in the anti-church Ilsimhoe Incident in 1934 and the 1938 movement to force Pastor Kim Eung-gyu to step down. However, after the Ilsimhoe Incident, the autonomous patient organization was reorganized in 1936, and the hospital president earned the right to appoint two executive committee members. Through this process, the hospital president strengthened the containment and control of patients’ autonomy, and the characteristics of a belief community were restored as the church came to operate the patient organization.
Second, this paper discusses the subjectivity of patients with Hansen’s disease at Aeyangwon. At Aeyangwon, the patients shared the power of the church by expressing their faith and directly elected ministers of 11 departments to form an executive committee. Through the direct election of representatives (executive committee members and ministers) of their autonomous organization, the patients participated in the operation of Aeyangwon and were able to resist the power of the church. In addition, the patients sought economic self-reliance through labor, built family houses, and maintained a family-based life. Although the autonomy of the patient organization had been reduced under the control of the church, patients used their voting rights to elect executive committee members and participated in the operation of their organization, which provided an institutional guarantee for the patients to exert their subjectivity.
The Integrated Metatheoretical Model of Addiction: Towards an Architectonic of a Metatheory of Addiction
Authors: Du Plessis Guy
Published: November 2022

In “The Routledge Handbook of Philosophy and Science of Addiction” Robert West highlights a pervasive challenge for more conceptual clarity and consensus within the field of addiction studies. In an attempt to address the challenge I provide the conceptual building blocks or architectonic of a metatheory of addiction, referred to as the Integrated Metatheoretical Model of Addiction (IMMA).  The IMMA is not a general theory of addiction, but rather an exploratory attempt at providing the architectonic of an metaparadigmatic heuristic, that may potentially provide the conceptual scaffolding needed for developing a general theory of addiction.
Possible Tetraquark Explanation for the Proposed T(2900)++ and T(2900)0 Structures
Authors: Bevelacqua Joseph
Published: November 2022

The recently proposed Tacs-bar0(2900)++ and Tacs-bar0 (2900)0 structures are investigated using a first-order tetraquark mass formula. This mass relationship is based on weakly bound Ds+ + π+ and Ds+ + π¯ meson clusters. The first-order tetraquark mass formula provides a range of mass and Jπ predictions based on Ds+ ground and excited states.
BunSay : Pusat Literasi Berbasis Kreativitas Pada Anak Usia Dini di TK Negeri Pembina Kabupaten Sukoharjo
Authors: Jumiastuti Erni , Hasanah Fathimah Nur , Hidayah Anisa Nur , Hartono Hartono
Published: November 2022

Tujuan dari penelitian ini adalah memberikan gambaran teoritis dan praktis tentang implementasi pembelajaran melalui pusat keBun Saya untuk meningkatkan kreativitas anak usia dini, yang akan dianalisis lebih lanjut. Alasan pemilihan strategi adalah kemampuan literasi anak masih rendah. Metode dalam penelitian ini adalah melalui pembelajaran pusat BunSay. Prosedur kerja yang dilakukan adalah dimulai deari perencanaan, pelaksanaan, pengamatan dan refleksi. Teknik pengumpulan data menggunakan lembar observasi, foto/dokumentasi kegiatan. Sedangkan untuk teknik analisis data menggunakan ? Anak yang   mendapat nilai ê3 dan ê4 X 100 % ? Jumlah anak dalam kelompok. Hasil dari pembelajaran melalui pusat BunSay ini adalah kemampuan literasi dan kreativitas anak berkembang sesuai harapan guru atau berkembang sangat baik. Hal ini dapat dilihat dari jumlah anak yang memperoleh nilai BSH atau Berkembang Sangat Baik dari kondisi awal 3 anak menjadi 8 anak.  Beberapa kendala yang terjadi di lapangan antara lain faktor pemeliharan, keamanan, alam, dan pendanaan, sedangkan faktor yang mendukung adalah fasilitas lahan yang ada, kerjasama dari guru, pengalaman dan kemampuan guru. Tindak lanjut dalam menerapkan pembelajaran ini adalah adanya upaya perbaikan, fasilitas pendukung lainnya. Simpulan melalui pembelajaran bercerita di pusat BunSay dapat meningkatkan kemampuan bercerita berbasis kreativitas anak usia dini di TK Negeri Pembina Kabupaten Sukoharjo.
Peningkatan Motivasi dan Kompetensi Guru Menyusun RPP Cooperative Learning Model Example Non Example Melalui Supervisi Akademik
Authors: Juwari Juwari
Published: November 2022

Penelitian ini bertujuan untuk  meningkatkan motivasi dan kompetensi guru dalam menyusun RPP Cooperative Learning Model Example Non Example melalui penerapan supervisi akademik bagi guru kelas di SD Negeri 1 Panggang Jepara Tahun Pelajaran 2018/2019.  Tempat penelitian di SD Negeri 1 Panggang Jepara. Subjek penelitian adalah  guru kelas 1,2, 3, 4, 5, dan 6 dengan jumlah 6 orang guru. Metode yang digunakan dalam penelitian ini adalah Penelitian Tindakan Sekolah (PTS). Tindakan yang dilakukan sebanyak dua kali dalam dua siklus. Tiap siklus terdiri dari empat tahapan yaitu: perencanaan tindakan, pelaksanaan tindakan, pengamatan tindakan, dan refleksi hasil pengamatan. Teknik pengumpulan data menggunakan dokumentasi, lembar observasi/pengamatan. Analisis data dalam penelitian ini menggunakan analisis deskriptif komparatif dengan membandingkan hasil kondisi awal dengan siklus I, dan siklus II dilanjutkan refleksi. Berdasarkan hasil penelitian dan pembahasan dapat disimpulkan bahwa penerapan supervisi akademik mampu membantu kepala sekolah meningkatkan motivasi dan kompetensi guru  menyusun RPP Cooperative Learning Model Example Non Example,  bagi guru kelas di SD Negeri 1 Panggang Jepara tahun pelajaran  2018/2019. Hal ini terlihat dari hasil penelitian dan pembahasan kondisi awal sampai siklus II. Nilai motivasi guru dalam menyusun RPP Cooperative Learning Model Example Non Example  dari siklus I ke siklus II terdapat peningkatan.
Penerapan Model Pembelajaran Double Loop Problem Solving untuk Meningkatkan Keaktifan dan Hasil Belajar Matematika pada Siswa Kelas XII MIPA 5 SMA Negeri 1 Gemolong Tahun Pelajaran 2022/2023
Authors: Prayitno Joko
Published: November 2022

Tujuan penelitian ini, yaitu 1) mendeskripsikan pelaksanaan pembelajaran Matematika dengan model pembelajaran double loop problem solving. 2) Menguji peningkatan keaktifan dan hasil belajar Matematika dengan model pembelajaran double loop problem solving. Penelitian ini merupakan penelitian tindakan kelas. Penelitian dilaksanakan pada Semester Gasal tahun pelajaran 2022/2023 di kelas XII MIPA 5 SMA Negeri 1 Gemolong Sragen. Hasil penelitian memperlihatkan bahwa penerapan model pembelajaran double loop problem solving dapat meningkatkan hasil belajar Matematika pada materi “turunan fungsi trigonometri” peserta didik kelas XII MIPA 5 SMA Negeri 1 Gemolong Sragen tahun pelajaran 2022/2023. Hal tersebut ditunjukkan oleh hasil belajar peserta didik pada tahap siklus I, dan siklus II yang mengalami kenaikan hasil belajar. Hasil belajar peserta didik meningkat sebesar 4,61 yaitu 79,86 pada siklus I dan 84,47 pada siklus II, sedangkan ketuntasan belajar peserta didik meningkat 22,22% yaitu 77,78% pada siklus I dan 100% pada siklus II. Rata-rata keaktifan belajar peserta didik meningkat sebesar 12,50% yaitu 72,92% pada siklus I dan 85,42% pada siklus II.
Peluang dan Tantangan Kurikulum Merdeka Belajar Menuju Era Society 5.0
Authors: Bungawati Bungawati
Published: November 2022

Pergeseran modernisasi pendidikan telah memasuki babak baru dalam sejarah pendidikan di Indonesia. Maka dari itu, dibutuhkan sebuah pembaruan dalam kurikulum untuk membekali mahasiswa dengan kemampuan pemecahan masalah dengan berbagai bidang keilmuan. Konsep merdeka belajar menjadi semangat baru dalam melakukan sebuah transformasi kebijakan demi tata kelola pendidikan yang lebih baik. Metode yang digunakan yakni studi literatur untuk menganalisis peluang dan tantangan kurikulum merdeka belajar menuju era Society 5.0. Konsep merdeka belajar merupakan komponen pendukung dari era Society 5.0 dengan memadukan kemampuan manusia dalam memanfaatkan perkembangan teknologi. Pada era Society 5.0 mengedepankan peran manusia yang memiliki keterampilan dengan harapan mampu merancang sebuah sistem untuk mengatasi permasalahan yang terjadi dalam masyarakat, mampu menciptakan kehidupan yang lebih baik serta menjaga kestabilan pertubuhan ekonomi. Dengan demikin setiap manusia akan menikmati kehidupan yang lebih berkualitas tanpa adanya kesenjangan usia, jenis kelamin maupun asal daerah.
Analisis Deskriptif Perbandingan Hasil Belajar Model Luring dengan Model BDR Sebelum dan Saat Pandemi
Authors: Nenobais Marlens Albert , Efendi Risal
Published: November 2022

Pandemi COVID-19 merupakan sebuah virus yang pemerintah menetapkan sistem partial lockdown, yakni dengan menerapkan kebijakan PSBB (Pembatasan Sosial Berskala Besar) dan juga PPKM (Pemberlakuan Pembatasan Kegiatan Masyarakat) sehingga berdampak pada semua sektor termasuk sektor Pendidikan. Penelitian ini bertujuan untuk dapat melihat perbandingan hasil belajar dari model luring dengan Model belajar dari rumah sebelum dan saat pandemi di SMP Negeri 2, Amanuban Barat. Pada penelitian ini Peneliti menggunakan jenis pendekatan Kuantitatif Komparatif. Subjek dalam penelitian ini yaitu siswa SMP Negeri 2, Amanuban Barat yang berjumlah 35 siswa. Dengan pengumpulan data melalui wawancara, observasi dan dokumentasi. Berdasarkan uji paired sample t test mendapatkan perbedaan nilai signifikansi sebesar 0,000 yang dimana < 0,05 Dari hasil penelitian pada mata pelajaran PJOK yang diterapkan secara Luring dan BDR ditemukan hasil penerapan Model Luring lebih tinggi dibandingkan Model BDR pada mata pelajaran PJOK.