bluuebunny/crossref_metadata_2025 huggingface dataset:
ECONOMIC CONSEQUENCES OF CYBERCRIME AND LEGAL REGULATION MECHANISMS IN GEORGIA
Authors: Makasarashvili Tamar , Khorguashvili Tea , Giguashvili Giuli , Sadagashvili Aleksandre
Published: November 2021

With the development of Internet technologies, cybercrime has also evolved and diversified. Much of the world's economic and business information comes from electronic information, and the need for remote work caused by the coronavirus (COVID-19) pandemic has further increased demand for e-services, which in turn has contributed to increased technology risks, threats, and incidents. The main task of the states is to actively fight against the negative socio-economic, financial, and political consequences caused by the growth of cybercrime. The main purpose of the study is to assess the negative consequences of cybercrime in Georgia, the main threats to information security, to develop recommendations for the prevention of cybercrime, to improve its legal regulation mechanisms. The fight against cybercrime in Georgia is carried out using criminal norms. The law "On Information Security" is in force in the country, Georgia's cyber security strategy has been developed, but this process needs constant development. The main task of the state is to gradually improve the legislation and bring it in line with modern technologies, to ensure close cooperation between the state and society, to raise the awareness of civil society. It is essential to constantly inform the public and companies about cyber threats, as effective prevention is the best form of crime prevention policy.
РROSРECTS OF THE DEVELOРMENT OF 5G TECHNOLOGIES IN COMРАRING TO LOWER BАND SYSTEMS
Authors: Prakhovnik Natalya , Zemlyanska Olena , Kachynska Natalya , Lisovskyi Kostiantyn , Butko Inna , Rochenovich Gleb-David
Published: November 2021

The article investigates the consequences of the development of 5g technologies in message with lower systems.
МОДЕРНІСТСЬКІ ІНТЕНЦІЇ МІФОТВОРЕННЯ В МАЛІЙ ПРОЗІ І. КОСТЕЦЬКОГО (ЗБІРКА «ОПОВІДАННЯ ПРО ПЕРЕМОЖЦІВ»)
Authors: Береза Анастасія , Пасько Ірина
Published: November 2021

У статті розглянуто міфотворення як засіб репрезентації соціально-філософських та естетичних інтенцій власного модерністського проєкту І. Костецького. На матеріалі авторської збірки «Оповідання про переможців» проведено інтерпретативний аналіз текстів з метою виявити функційні особливості міфотворення як художнього методу, характеризувати основні модерністські дискурси малої прози І. Костецького.
ЧЕСЬКО-УКРАЇНСЬКИЙ І УКРАЇНСЬКО-ЧЕСЬКИЙ МОВЛЕННЄВИЙ ЕТИКЕТ: ЗІСТАВНИЙ АНАЛІЗ
Authors: Зайченко Неоніла , Паламарчук Ольга , Антоненко Оксана
Published: November 2021

У статті висвітлюються лексико-граматичні, стилістичні й модальні особливості співвідношення основних функціональних одиниць чесько-українського та українсько-чеського мовленнєвого етикету. Проаналізований мовний матеріал свідчить, що існують суттєві відмінності у формулах чеського та українського мовленнєвого етикету, які детерміновані розбіжностями у граматичній структурі обох мов.
PROSPECTIVE STUDY OF THE EFFECTIVENESS OF DIFFERENTIATED THERAPY OF ENDOMETRIUM HYPERPLASIA WITHOUT ATYPIA IN WOMEN IN REPRODUCTIVE AGE
Authors: Khaskhachykh D. , Potapov V. , Kukina G. , Garagulya I.
Published: November 2021

The paper considers the issues of improving the effectiveness of treatment of endometrial hyperplasia without atypia in women of reproductive age with the use of progestins as a pathogenetic therapy and should be personalized (targeted) taking into account the receptor sensitivity of endometrial tissue to progestins. The positive effects of progestin use are mainly due to the expression of progesterone receptors in the endometrial tissue, which must be taken into account during hormone therapy. A prospective study was performed in 60 patients of reproductive age with abnormal uterine bleeding, who according to the results of histological examination of endometrial tissue was diagnosed with endometrial hyperplasia without atypia. All patients were treated with micronized progesterone at a dose of 400 mg / day continuously for 6 months. To determine the effect of the use of progestins was performed by studying the expression of receptors for estrogen (ER) and progesterone (PR) in histological blocks of the endometrium by immunohistochemistry. In all women there was a significant expression of EP in endometrial cells, which led to its proliferative activity against the background of reduced expression of progesterone receptors by 65%, which caused no effect of therapy in 25% of women. Studies have shown that when deciding on the appointment of micronized progesterone for the treatment of endometrial hyperplasia without atypia, it is recommended to study the expression of progesterone receptors in endometrial tissue to clarify the possibility of a pharmacological effect. Treatment of endometrial hyperplasia without atypia with progesterone drugs is not effective in low expression of progesterone receptors in endometrial tissue. Based on this, we can identify a group of women with progesterone-resistant hyperplasia who require other treatments.
POLYMORPHOUS LIGHT ERUPTION AND ITS ASSOCIATION WITH HYPOTHYROIDISM AND AUTOIMMUNE THYROIDITIS – A COMPARATIVE CROSS-SECTIONAL STUDY
Authors: Brewin C Jerriton , G David Brinda , Menon Roshni
Published: November 2021

BACKGROUND In many parts of the world, polymorphous light eruption (PLE) is the commonest cause of
photosensitivity. Previous studies have suggested the association of PLE with multiple autoimmune
diseases. Few studies are available suggesting the association of PLE with autoimmune thyroiditis. We have undertaken this
study to conrm such an association and to predict which cases of PLE are likely to have hypothyroidism and autoimmune
thyroiditis.
METHODS This was a cross-sectional study with comparative group with 75 PLE cases and 75 controls. Thyroid function test
(TFT) was done for all subjects and, if found abnormal, anti-thyroid peroxidase (TPO) antibodies were tested. The studied
parameters were compared using Pearson's chi-squared test for signicance.
RESULTS The male to female ratio was 1:2.1. Hypothyroidism and autoimmune thyroiditis were signicantly present in PLE
cases. PLE lesions with papular morphology, persistent and recurrent PLE, positive family history and associated other
autoimmune diseases were signicantly associated with autoimmune thyroiditis.
CONCLUSION PLE is signicantly associated with hypothyroidism and autoimmune thyroiditis. Hence we suggest screening of
PLE patients for hypothyroidism and, if required, for autoimmune thyroiditis for early diagnosis and treatment.
A STUDY OF PROFILE OF MULTIDETECTOR COMPUTED TOMOGRAPHY IN MAXILLO-FACIAL INJURIES IN A TERTIARY CARE CENTER
Authors: Shivprasad Kakani Saurabh , Padiya Saurabh , Surywanshi Asmita , Patel Ejaj
Published: November 2021

Maxillofacial injuries account for a large group of patients in the emergency department in tertiary care
hospital, presenting as an isolated injury or a part of poly trauma. Road trafc accidents are the
commonest cause of maxillofacial injuries. Such injuries are clinically important as they cause facial disgurement and thus
imposing emotional, morbidity and cosmetic dependence. To observe these fractures and decide appropriate management
lines, there is a need for imaging aid. The main purpose of imaging guidance is to nd and characterize the fractures and
associated injuries.
Aim:Study of prole of multi detector computed tomography in maxillo-facial injury in a tertiary care centre.
Materials and methods:
The cases coming to the emergency department and then forwarded to department of Radiology, MGM medical college and
hospital, Aurangabad for CT scan formed the source of the data and were studied in detail. Detailed history of the cases was
taken. Written and informed consent were taken for undergoing CT scan examination. Patients were scanned using 16 slice
Toshiba acquilion machine. The data was tabulated and observed and conclusions were made.
Results: Total 175 number of patient were included in the study and CT scan for maxillo-facial injuries were conducted.
Diagnosis of the maxillofacial injuries were done and the fractures were classied according to age, gender, location and its
subsets. According to our study 21-30 years of age group was the most common age group to be involved in maxillo-facial
injuries. Frequency of maxillo-facial injuries was found to be more in male than female. Maxillo facial injuries occurred mostly
due to road trafc accidents. Orbit was seen as the most common bone to be fractured followed by fracture of maxilla bone.
Orbital wall fracture happen to be overall most common bone affected amongst all the other facial bones.
Economic Impact of Unilateral Free Trade
Authors: Narain Jalan Aarnav , Bajaj Anshika
Published: November 2021

President Donald Trump condemned the interdependence of
the United States with other countries in a speech on March
24th, 2020 saying, “This crisis has underscored just how
critical it is to have strong borders and a robust manufacturing
sector. - ''… Our goal for the future must be to have American
medicine for American patients, American supplies for
American hospitals, and American equipment for our great
American heroes.” [1] The United States has also been part of
the ongoing US-China trade war, with both sides imposing
numerous tariffs on each other's imports. These actions speak
to the protectionist economic policies of the Trump
administration.
CUTANEOUS MANIFESTATIONS OF HIV IN PEOPLE LIVING WITH HIV/AIDS AT TERTIARY CENTRE
Authors: Agrawal Anubhav , Dube Simmi , Tejwani Aditya
Published: November 2021

BACKGROUND-The study was conducted to describe systematic clinical manifestations among HIV in
PLHA at tertiary care centre.
METHODOLOGY- This study was designed as cross sectional study at Department of Medicine, tertiary care centre. A total of
100 HIV infected patients were included detailed enquiry about presence of skin lesions along with CD4 cell count was obtained
and entered in pretested questionnaire
RESULTS-The mean age of patients with HIV was 43.9±10.2 years and Slight female preponderance was observed with male:
3
female ratio of 0.89:1. Mean CD4 count was 243.2±103.2 cells/mm . Majority of patients had CD4 count in the range of less than
3 200 cells/mm (64%) Staphylococcal skin infections were the most common skin lesions observed in 34% patients. All the
patients with cutaneous manifestations presented in present study had low CD4 cell count. However, no statistically signicant
association between CD4 count and cutaneous manifestations could be documented (p>0.05).
CONCLUSION-Cutaneous manifestations are more prevalent in patients with lower CD4 counts and can also be observed with
normal CD4 count levels amongst patients with HIV. Occurrence of cutaneous manifestations was higher in patients with lower
CD4 count but the observed difference was not statistically signicant.
EFFECT OF BREAST MILK ADMINISTERED ORALLY AS MINIMAL ENTERAL NUTRITION PRIOR TO TUBE FEEDING (OMEN) IN PRETERM INFANTS – SINGLE CENTER RANDOMIZED CONTROL TRIAL
Authors: U Kalane Shilpa , Rajhans Arti P , V Joshi Rajan , Devaskar Uday P , G Kanade Nandkumar
Published: November 2021

BACKGROUND: Safety and clinical benets of early Minimum Enteral Nutrition (MEN) have been
demonstrated by several trials. MEN is administered as tube feed bypassing the oral phase of digestion.
Oropharyngeal administration of colostrum has shown positive trend to achieve feed tolerance. Aims: To study the effect of
early initiation and subsequent continuation of minimal oral feeding prior to tube feeds on duration to achieve of full enteral
feeds.
METHODOLOGY: DESIGN: Open label RCT. Setting: Tertiary level care NICU. Participants: Hundred preterm very low birth
weight neonates with no anomaly. Intervention: Infants received 3mL/kg/d of breastmilk or nothing via oral route q2h,
beginning within 24-48h of birth which was continued until oral feedings initiated. In both groups tube feeds were introduced
(10 ml/kg/d within 24-96 h) & increased (10-20 ml/kg/d) until 180 ml/kg/d. Oral feeding was based on infants cues and a post
menstrual age of ≥32 week or weight ≥1250 gram. Outcome: Primary: Time to reach full tube feeds (days). Secondary: NEC,
sepsis, mortality, and duration of hospital stay. Duration: 1 year.
RESULTS: Infants in OMEN group reached full enteral feeds earlier (14.2 ± 9.0 vs 18.8 ± 11.8, p 0.03) and were discharged at
relatively younger post menstrual age compared to those in the TMEN group. There was no signicant difference in the
incidence of NEC, sepsis and mortality.
CONCLUSION: Administration of small quantity of human milk orally before each tube feed led to earlier achievement of full
volume enteral feeds.
IMPACT OF ACADEMIC STRESS AND EMOTIONAL MATURITY ON MENTAL HEALTH AMONG NURSING COLLEGE STUDENTS
Authors: Swarnalatha T. , Janardhanam V.
Published: November 2021

An attempt was made in the present investigation to study the impact of academic stress and emotional
maturity on mental health among nursing college students. Sample of the present study consists of 120
nursing college students in East Godavari District of Andhra Pradesh State. Students Academic stress scale developed by
Kumar Reddy (1999), emotional maturity scale developed by Yashvir Singh and Mahesh Bhargava (1990) and mental health
inventory developed by Jagadish and Srivastava (1983) were administered. The ndings of the study revealed that academic
stress and emotional maturity have signicant inuence on mental health.
Kinetics of α-amylase and α-glucosidase Inhibitory Potential of Hermannia geniculata Eckl. & Zehl root Extracts Used in Basotho Traditional Medicine.
Authors: Adeniran L. A. , Ashafa A. O. T.
Published: November 2021

The scientific investigation of the folkloric use of Hermannia geniculata roots in the management of diabetes mellitus was conducted. Phytochemical analyses, in vitro antioxidant and hyperglycaemic studies were carried out on the crude extracts of H. geniculata. Qualitative phytochemical analysis revealed the presence of saponins, phenols, flavonoids, alkaloids, tannins, phytosterols, triterpenes and anthraquinones. The ethanol extract exhibited the highest free radical scavenging capability with the lowest IC values (0.52, 0.38, 0.59, 0.63, 0.39) mg/mL for 50 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2-Azino-bis(3-ethylbenzothiazoline-6-Sulphonic acid (ABTS), hydroxyl radical, superoxide anion radical and metal chelating ability which is significantly different (p<0.05) from the standard (silymarin). In antidiabetic studies, ethanol extract is a potent inhibitor of α-glucosidase (IC : 0.15 mg/mL) which is lower and significantly 50 different (p<0.05) from the standard (acarbose) IC value of (0.52 mg/mL). Ethanol extract 50 exhibited a milder inhibition of α-amylase enzyme with IC (0.57mg/mL) which is higher and 50 significantly different (p<0.05) from acarbose with IC (0.47 mg/mL). Kinetic studies revealed H. 50 geniculata ethanol extract exhibited competitive inhibition of α-amylase and uncompetitive inhibition of α-glucosidase enzymes. All these findings provided the scientific basis which support the use of the root extract of H. geniculata in the management of diabetes mellitus and oxidative stress induced ailments like colitis and ulcers by the Basotho traditional medicine of South Africa.
Investigation of some aspects of the Neuro-Morphometry of the African catfish (Clarias gariepinus)
Authors: Usende I. L
Published: November 2021

The brain is one of the most important organs, as it controls numerous bodily functions. Due to its crucial regulatory roles, the nervous system of fishes and especially the brain needs more research. Catfish (order Siluriformes or Nematognathi) are ray finned fish, named for their prominent whiskers (barbels), which resembles the whisker of a cat. The Nigerian cultured catfish (Clarias gariepinus) have small eyes and wide mouths, which suggest low dependence on vision, nocturnal activity, and predatory habits. Herein, we describe the gross morphology and morphometrics of the brain of Clarias gariepinus. Five apparently healthy adult catfish (Clarias gariepinus) without sex differences were used. Cranial nerves and spinal cord were severed as the brain case was removed, after which all the morphological descriptions were done. Ten morphometric parameters were also measured. The generated data were graphically illustrated with scatterplot and biplot, as well; the regression analysis showing the stepwise fit for the prediction of the brain weight from other measured parameters was also presented. The olfactory bulb is large, somewhat rounded and rostral. The cerebellumin all examined brain was the largest structure of the brain with a cerebellar length and width of 1.16±0.11 cm and 0.82±0.03, respectively. The optic tectum, lobusvagi, lobusfacialis and eminentiagranularis were also well developed but small in size. Although, the behavior of the catfish (Clarias gariepinus) is still unknown, the relative proportion of the cerebellum, optic tectum, eminentiagranularis, lobusfacialis and lobusvagi, might be related to carnivory and an enhanced capacity for food selection in this species. In conclusion, the report herein has helped to provide useful information for the first time on morphology of the brains of Clarias gariepinus cultured in Nigeria, for understanding of the neurobehaviour and habits of this species.
Seasonal Fluctuations In Luteinizing Hormones (lh), Follicle Stimulating Hormones (FSH) And Testosterone Levels In Male African Giant Rats.
Authors: Olawuwo O. S
Published: November 2021

As part of the several efforts to understand the biology of the African Giant rats (AGR) (Cricetomys gambianus), seasonal changes in the gonadotropin and testosterone levels of the adult male African giant rats of about 1 – 1½ years of age in captivity were investigated during wet and dry seasons in the tropics. Male giant rats (n = 10) were kept for 12 months and blood samples were collected monthly (on 15th of each month), during the dry (November – February) and wet (March – June) seasons for Luteinizing hormone (LH), follicle stimulating hormone (FSH) and testosterone assays. The hormones’ levels were evaluated to suggest the best breeding season for giant rat in South-West Nigeria. The result showed that there were significant variation (p<0.001) in LH and FSH levels in the giant rat in the wet season when compared with the dry season. However, testosterone level was significantly lower (p<0.001) in the wet season than in the dry season. The study showed that sexual activities in the male AGR might be higher in the dry season with peak activities in December in the tropics while the gonadotropins prepare the animals for sexual activities in the dry season. Further studies on the seasonal activities of gonadotropins in the female will give more insight into the sexual receptivity and performance in these animals.
Space-Time-Color (STC) Scheme with Symbol-Hopping for Color Shift Keying (CSK)Modulation
Authors: Ximenes Leandro , Arthur Rangel , Rodrigues igor Santos Cruz
Published: November 2021

This paper proposes a novel coding scheme for Visible Light Communications (VLC) systems using symbol mapping permutations on the color domain. The permutation is done through symbol-hopping over the points of an optimized 4-CSK constellation. This scheme provides diversity gains, promises robustness against monochromatic channel degradation, and increases the information security of the communication link. It can also be used in conjunction with Single-Input and Single-Output (SISO) systems, as well as in Multiple-Input and Multiple-Output (MIMO) systems. Monte Carlo computational simulations evaluate the performance of the proposed scheme over the conventional QuadLED (QLED) CSK system and other codes, showing superior coding and diversity gains over two direct competitors, under a Rician ﬂat-fading channel.
Hardware Design of a Tele-EEG Device For Detection of Neurophysiological Condition
Authors: Aminaie Pouya , Aminaie Poorya
Published: November 2021

The main idea of this research originates from the patients such that each patient with neural disorder should refer to a medical center to check his brain's health condition to sample his EEG signals and present the results to a specialist for further investigation. If this process can be done remotely by tele-medicine techniques, it will save cost and time. In tele-medicine method, the patient can record the EEG signal alone at home and send the results to his physician. To this end, this research employs Bluetooth to connect the interface system to the computer, and the patient can send the results to his physician after saving the data. Thus, the main purpose of designing this BCI system is to record EEG signals using a microcontroller and transmit them via Bluetooth to a computer and mobile phone such that the signal can be represented instantaneously in a GUI.
The Effectiveness of Quantum Learning Methods in Group Guidance to Improve Student Motivation in Class VIII A MTS Darul Ulum 2 Widang
Authors: Antariksa Freda Angga
Published: November 2021

For human life, motivation is very important, including student motivation as a driving force in the spirit of learning. The purpose of this study was to determine the effect of student motivation with the quantum learning method in group guidance to increase student learning motivation. One group pre-test design is the design used in this study on the population of 16 students of class VIII-A. The data analysis technique used by this researcher is a non-parametric analysis using the Wilcoxon test. The result of interpretation using the Wilcoxon test is known that Asymp. Sig (2-tailed) is 0.046. Because the value of 0.046 is smaller than <0.05, it can be concluded that Ho is rejected and Ha is accepted. it can be concluded that there is an effect of the quantum learning method in group guidance to increase the learning motivation of class VIII A students of MTs Darul Ulum 2 Widang
Targeting the Prion-Like Aggregation of Mutant p53 to Combat Cancer
Authors: Elena Locci  , Silvia Raymond
Published: November 2021

The team first screened a set of protein mimics originally designed to target Alzheimer's disease and type 2 diabetes. The results identify a mimicry of the protein that potentially isolates the mutated p53 material and prevents further protein accumulation. The researchers then showed that segregation of mutated p53 grains by protein mimicking restored the suppressive function of the p53 tumor, leading to the death of a wide range of cancer cells. Importantly, protein mimicry therapy effectively reduces tumors that contain mutated p53 while showing no significant toxins for healthy tissue, resulting in significantly longer survival. "As the prevalence of cancer increases worldwide, there is an urgent need for new cancer therapies to complement or replace existing therapies," said the study's lead author. Here we show the first successful use of a small molecule amyloid inhibitor as an anticancer agent. We believe that this will have a far-reaching impact, as it effectively bridges the gap between amyloid disease and cancer and is the basis for passing on information approaches in the design of new and robust cancer mutation therapies for the p53 mutation.

Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management
Epigenetic Regulation of Hematopoiesis and Acute Leukemia
Authors: Elena Locci  , Silvia Raymond
Published: November 2021

The cell cycle of such a subject has been thoroughly studied, yet here we are examining for the second time that we have entered a new phase; Biology always has new insights to show us. This data was amazing. This map is based on this beautiful circular pattern that we have identified as all the different stages of the cell cycle. Have a disease. When Placer and colleagues used the ccAF tool to analyze cell data for glioma tumors, we found that tumor cells were often in the G0 or G1 nerve growth state. With tumor aggression, fewer cells remain at rest in the G0 nerve state. This means that more cells are growing and growing in the tumor.

Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management
Investigation of DNA Damage Induced by Alkylating Agents and Repair Pathways by Cooperating Mechanisms Driving the Formation of Colorectal Adenomas and Adenocarcinomas Using DNA Alkylation and DNA Methylation
Authors: Elena Locci  , Silvia Raymond
Published: November 2021

In this recent study, DNA data from 900 patients with colorectal cancer were reviewed. Analysis of the data showed a distinct mutation signature, a pattern that had never been identified before but indicated a type of DNA damage called "alkylation." Red meat contains chemicals that can cause alkylation. High levels of tumor alkylation damage are seen only in patients who consume an average of more than 150 grams of meat per day, roughly equivalent to two or more meals. On the other hand, a group of researchers in 2019 in a controversial conclusion stated that they do not have much confidence in reducing deaths from colon cancer by avoiding red meat.

Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management
Progress and Challenges of Nanoparticle-Based Drug Delivery for Therapy of Lung Cancer
Authors: Elena Locci  , Silvia Raymond
Published: November 2021

According to the results of a global phase 2 clinical trial, the new drug sotorasib reduces tumor size and promises to improve and increase survival in patients with lung tumors caused by specific DNA mutations. It is designed to counteract the effects of mutations that are seen in about 13% of patients with non-small cell lung adenocarcinoma (a common type of lung cancer). The Food and Drug Administration (FDA) on May 28 approved the drug as a targeted treatment for patients with small cell lung cancer whose tumors express a specific mutation called G12C in the KRAS gene. Small cell lung cancer accounts for more than 80% of lung cancers. More than 200,000 new cases of non-small cell lung cancer are diagnosed in the United States each year.

Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management
Environmental Regulation and High-Quality Development in China
Authors: Xu Wentao
Published: November 2021

This paper uses the data of 30 provincial regions in mainland China except Tibet from 2006 to 2018 to weighted measure the intensity of environmental regulation through the weight determined by the ranking of pollutant emission intensity year by year; Based on the three subsystems of economy, society and environment, this paper constructs a high-quality development measurement index system, and determines the weight year by year by entropy method, as well as measures the high-quality development level by weight; From the perspective of enterprise production decision, the influence of environmental regulation on high-quality development is theoretically deduced. Through the empirical test of two threshold models with environmental regulation intensity and per capita GDP as the threshold, it confirms each other, and empirically analyzes the impact of environmental regulation intensity on high-quality development level. The research results show that: The impact of environmental regulation intensity on high-quality development level, with the change of enterprises’ decision-making to deal with environmental regulation, has an obvious threshold effect. Before reaching the threshold, the increase of environmental regulation intensity has a negative impact on high-quality development; After reaching the threshold, the impact of the increase of environmental regulation intensity on high-quality development may have a short uncertain stage, followed by a positive impact. Government environmental regulation should be combined with the local stage to avoid the misunderstanding of blindly improving the intensity of environmental regulation; Government environmental regulation should focus on reducing the cost of cleaner production and technological innovation, and accelerate the formation of “forced“ innovation mechanism of environmental regulation, so as to give full play to the positive role of environmental regulation in promoting high-quality and high-development.
Implementación de una aplicación para el análisis dosimétrico de planes de radioterapia externa basada en la API de Eclipse
Authors: Valgoma Solanas Jose Agustín , Pereda Barroeta Naia , Fernández Montes Manuel , Montejo Arteche Ariane , Conejo Monasterio Francisco Javier , Sánchez Hernández Nuria
Published: November 2021

Tradicionalmente, durante la evaluación de un plan de radioterapia se analizan índices dosimétricos de los volúmenes contorneados empleando diversas utilidades comerciales. Para facilitar esta labor repetitiva y tediosa, y adaptarla a cada departamento, el sistema de planificación Eclipse ofrece al usuario la posibilidad de crear programas informáticos (scripts) con la ayuda de una interfaz que explora la información dosimétrica del plan.
Presentamos un script de Eclipse realizado con elementos gráficos de Windows para el análisis de planes de radioterapia externa en nuestro hospital. Consideramos que este trabajo puede servir de ejemplo y resultar de utilidad para los profesionales usuarios de Eclipse.
Dosimetría por imagen en radioembolización hepática con Y90: impacto de la resolución espacial del PET.
Authors: Carrasco Vela Nuria , Tejedor Aguilar Natalia , Giménez Gómez Vicente , Torres Espallardo Irene
Published: November 2021

La imagen PET es crucial en la dosimetría de tratamientos de radioembolización hepática con Y90. Sin embargo, dada la limitada resolución espacial de estos escáneres, la distribución real de actividad se difumina. Suele argumentarse que este difuminado es mayor que el debido a la  convolución con un kernel de dosis (algoritmo VSV) de tal modo que el método de deposición local (LDM) proporciona resultados  suficientemente precisos. En este trabajo hemos comparado los resultados dosimétricos de LDM, VSV y Monte Carlo en imágenes PET  generadas matemáticamente a las cuales se les ha aplicado difuminados que simulan la resolución espacial del PET.
"The Room Was Quite Small by American Standards": Are Online Hotel Reviews Culture Specific?
Authors: Nielsen Martin , Zethsen Karen K.
Published: November 2021

Hotel bookings are increasingly made online, and many travelers rely on eWOM in the form of peer hotel reviews. These reviews potentially contain information of great relevance to the tourism industry and offer a unique and ever-expanding corpus of unsolicited data. If these data are
investigated systematically, it may provide insights that would enable hotel managers to be proactive in their marketing. The present study focuses on the underresearched area of the potential impact of nationality on the reviews. Using a corpus of authentic American and German hotel reviews
and the qualitative, phenomenologically inspired method of systematic text condensation, this study investigates the impact of national culture on review comments in order to establish whether nationality makes a difference for the themes and attitudes expressed. The data indicate that Americans
are more likely to focus on old-world charm, romance, physical comfort, personal service/relations, and problemsolving than are Germans. The overall results of this qualitative study allow us to conclude that there are indeed differences between the German and the American reviews to a degree
that is worth pursuing in future mixed-methods research and that may have practice implications for hotel managers.
DEVELOPMENT OF IMMUNOCHEMICAL SYSTEMS TO CONTROL AUTHENTICITY AND COMPOSITION OF MEAT PRODUCTS
Authors: Zvereva E.A. , Hendriсkson O.D. , Popravko D.S. , Dzantiev B.B.
Published: November 2021

Immunochromatographic test systems with rapid sample preparation have been developed for testing the composition of meat products, which ensure the identification and assessment of the content of muscle tissues from different groups of animals. It was shown that the technological processes of enzymatic and heat treatment did not impair the selective detection of biomarkers.
PHYSIOLOGICAL AND BIOCHEMICAL EVALUATION OF THE EFFECTIVENESS OF A NEW FOOD INGREDIENT: A SOURCE OF PHYTOECDYSTEROIDS AND FLAVONOIDS FROM QUINOA GRAIN
Authors: Petrov N. , Zorin S. , Biryulina N. , Sidorova Y.
Published: November 2021

A new food ingredient has been developed - a source of phytoecdysteroids and flavonoids from quinoa grain. A physiological and biochemical assessment of its effectiveness under conditions of chronic immobilization stress and a single e exhausting physical activity was carried out. A pronounced adaptogenic effect of the developed food ingredient was shown.
NEW FOOD PRODUCTS WITH PROBIOTIC YEAST
Authors: Khramtsov A.G. , Sazanova S.N.
Published: November 2021

Saccharomycete yeast can be an alternative to traditional probiotics. The beneficial properties of Saccharomyces boulardii are well understood. By adding this yeast to food products, you can enrich them with functional ingredients. A method for producing ice cream with probiotic yeast has been developed.
TECHNOLOGY TO CULTURE YEASTS IN CULTURE MEDIA OF CUP PLANT GREEN MASS
Authors: Tsugkieva V.B. , Khoziev A.M. , Dzantieva L.B. , Soldatova I.E.
Published: November 2021

It has been found that the cup plant green mass is a promising substrate to culture yeasts. This plant in the Republic of North Ossetia-Alania is a perennial, high-yield introduced species, yielding up to 1500 cwt of green mass per hectare. Using the cup plant green mass to culture yeasts is economically preferable, due to the high nutrient content.
DEVELOPMENT OF A SYSTEM FOR MONITORING AND PRESERVATION OF GENETIC RESOURCES ON THE EXAMPLE OF ABORIGENOUS GOATS OF THE ALTAI MOUNTAINS OF MONGOLIA
Authors: Voronkova V.N. , Beketov S.V. , Stolpovsky Yu.A.
Published: November 2021

The origin of genetic resources domesticated by a species of animals, their importance in the development of fundamental biology and economics is considered on the example of a domestic goat. The data on genetic risks and population structure of local goat breeds inhabiting the territory of Mongolian Altai, obtained by analyzing SNP genotypes, microsatellite sequences, as well as the mitochondrial genome and genes of the Y chromosome, are presented.
GENERATION OF POTATO PLANTS WITH AN EDITED GENOME AND ALTERED STARCH METABOLISM
Authors: Slugina M.A. , Efremov G.I. , Kochieva E.Z. , Kamionskaya A.M. , Shchennikova A.V.
Published: November 2021

Potato plants with the edited genome were obtained. Edited lines are characterized by changes in root gravitropism, aboveground part development and starch metabolism.
RUSSIAN SCHOOL-CONFERENCE "ECOTOXICOLOGY" - A KEY ELEMENT FOR ATTRACTING STUDENTS TO SOLVE INNOVATIVE TASKS OF ENVIRONMENTAL PROTECTION BIOTECHNOLOGY
Authors: Alferov V.A. , Osina K.V. , Boronin A.M.
Published: November 2021

The leading forms of recruiting the gifted youth to solution of innovative tasks are scientific workshops and conferences. The Russian Young Scientist School-Conference “Ecotoxicology” has been held in Tula State University since 2006, and it plays an important role in training biotechnologists in environmental field of research.
ANTIMICROBIAL EFFECT OF SPECIES OF MINT GROWING IN THE SOCHI BLACK SEA REGION
Authors: Rybalko A.A. , Rybalko A.E. , Agumava A.A.
Published: November 2021

Research has been carried out to develop a technology for in vitro production of M. longifolia and M. spicata plants growing in the Sochi Black Sea region to obtain biomass as a source of medicinal substances. By the method of polymerase chain reaction, an inhibitory effect on enteropathogenic Escherichia coli has been established.
Psychological Adaptation among Students with Learning Disabilities in English from the Perspective of Their Teachers in Light of the Corona Pandemic
Authors: Khasawneh Mohmmad
Published: November 2021

The study identified the level of psychological adaptation of students with learning disabilities in English from their teachers’ perspectives. The study aims to achieve results to develop treatment programs for children with learning disabilities in English to help them move away from shyness, fear, and symptoms of social inadequacy in general and psychological adaptation in particular. It can also have a preventive value represented in discovering and assisting children who suffer from psychological maladaptation. The descriptive approach was used in this study and a questionnaire was developed as an instrument. Its validity and reliability were ensured and then applied to as ample of 30 teachers from Irbid city, Jordan, for the academic year 2019/2020. The results of the study indicated that there were statistically significant differences in the level of psychological adaptation among those with LDs in English from the point of view of their teachers. There were differences according to the gender variable in favor of females. In light of the results, the study recommends conducting scientific studies on psychological adaptation with variables other than the variables used in the research.
RESIDENTIAL BUILDING AS EVIDENCE OF WEALTH OR POVERTY IN RUSSIAN PROVERBS AS COMPARED TO CHINESE ONES
Authors: Селиверстова Елена Ивановна , Ван Исюань
Published: November 2021

Жилище является одним из важнейших элементов культуры, связанных с материальными потребностями и аксиологическими ценностями этноса. В предлагаемом исследовании, ориентированном на выявление идейного своеобразия паремий и ценностного восприятия жилого строения носителями русской и китайской культур, используется метод лингвокультурологического анализа. В центре внимания - компоненты пословицы-наименования жилых строений богача и бедняка и те представления, что проявляются в паремиях двух языков. Результаты проведенного анализа показывают, что наименования жилища, используемые в двух языках, широко представлены в паремиях, что говорит о его важности в жизни человека; они служат для указания на материальное состояние его владельца, для выражения отношения к жилищу и расстановки ценностных приоритетов носителей языка и культуры. С одной стороны, в русских и китайских паремиях выражается ряд общих лингвокультурологических установок: негативное отношение к богатому жилью, тесно связанное с идеей социального неравенства; предпочтительность собственного жилья качественному, но чужому и др. С другой стороны, в китайских паремиях более ценным представляется моральное состояние собственника, его образованность и перспективы, а в русских паремиях акцентируется важность здоровья, любви и согласия и т. д.

Dwelling is one of the most important elements of culture associated with the material needs and axiological values of the ethnos. In the proposed study, focused on identifying the ideological specifics of the paremias and the value perception of the dwelling by representatives of Russian and Chinese cultures, the method of linguocultural analysis is used. The focus is on the components of the proverb-names of the rich and poor residential buildings and those ideas that are expressed by the proverbs of the two languages. The results of the analysis show that the names of the dwelling, used in two languages, are widely represented in paremias, which proves its importance in human life; they serve to indicate the material condition of its owner, to express the attitude towards the dwelling and to set the value priorities of native speakers of the proper language and culture. On the one hand, a number of common linguocultural attitudes are expressed in Russian and Chinese paremias: a negative attitude towards rich housing, closely related to the idea of social inequality; a positive assessment of one’s own poor housing, compared with high-quality, but somebody else’s, etc. On the other hand, in Chinese paremias, the moral state of the owner, his education and prospects are more valuable, while in Russian paremias the importance of health, love and harmony, etc. is emphasized.
Enhancement of Chondrogenesis in Hypoxic Precondition Culture: A Systematic Review
Authors: Rhatomy Sholahuddin , Setyawan Riky , Romulo Michael Aaron
Published: November 2021

BACKGROUND: Cartilage tear has begun to be treated with stem cells. However, stem cell oxygen level culture has not been evaluated for the best environment to enhance chondrogenesis.

AIM: The purpose of this review is to focus on the hypoxic oxygen level of stem cells culture as a treatment for cartilage tear.

METHODS: A literature search was systemically conducted on PubMed (MEDLINE), OVID, EMBASE, the Cochrane Library, Scopus, Web of Science, Science Direct, Wiley Online Library, Google Scholar, and bibliography of selected articles with the terms (“culture”) AND (“stem cell” OR “mesenchymal stem cell” OR “MSC”) AND (“hypoxic” OR “hypoxia”) AND (“cartilage” OR “chondro*”) as the main keywords. A total of 438 articles were reviewed. Thirty-six articles were considered relevant for this systematic review.

RESULTS: The result of this review supports stimulation effects of hypoxic oxygen level stem cell culture in chondrogenesis process. Most studies used 5% oxygen concentration for culture, both of in vivo and in vitro studies. Due to the heterogeneity nature of the included studies, meta-analysis was unable to be conducted.

CONCLUSION: Hypoxia state seems to play an important role in chondrocytes proliferation, differentiation, and matrix production.
La continuité référentielle dans le corpus RÉSOLCO : méthode d’annotation et premières analyses
Authors: Garcia-Debanc Claudine , Rebeyrolle Josette , Ho-Dac Lydia-Mai
Published: November 2021

Le corpus RésolCo est constitué de 400 textes rédigés par des élèves français âgés de 9 à 15 ans en réponse à une consigne d’écriture conçue comme une tâche impliquant la résolution de problèmes de cohésion. Cette contribution expose une méthode d’annotation de la continuité référentielle dans la désignation des personnages principaux d’un texte narratif et l’illustre avec l’analyse de trois textes d’élèves. Les configurations de marques linguistiques observées sont interprétées comme indices de la stratégie des rédacteurs. Sont présentés les premiers résultats de l’analyse d’une centaine de textes de trois niveaux contrastés (CE2, 6 e  et 3 e ).
Gérer la cohérence textuelle sur le plan structurel : analyse d’écrits d’étudiants en L1
Authors: Jacques Marie-Paule , Pallanti Luca
Published: November 2021

Nous prenons appui sur un corpus de textes de scripteurs peu experts, des étudiants primo-entrants à l’université, titulaires de bacs professionnels du secteur industriel, pour analyser la contribution des marqueurs de structuration et d’organisation textuelle à la cohérence du texte. Nous faisons l’hypothèse que ce qui crée de la cohérence est plus la convergence des marques que leur stricte présence. Dans notre corpus, 43 % des textes ne parviennent pas à faire coopérer ces marques. Les quelques scripteurs qui détournent la consigne d’écriture font globalement converger les marques et produisent des textes plus aboutis.
NECS-based Cache Management in the Information Centric Networking
Authors: Fethellah Nour El Houda , Bouziane Hafida , Chouarfia Abdallah
Published: November 2021

The Information Centric Networking ICN architectures are proposed to overcome the problems of the actual internet architecture. One of the main straight points of the ICN architectures is the in-network caching. The ICN performance is influenced by efficiency of the adopted caching strategy which manages the contents in the network and decides where caching them. However, the major issue which faces the caching strategies in the ICN architectures is the strategic election of the cache routers to store the data through its delivery path. This will reduce congestion, optimize the distance between the consumers and the required data furthermore improve latency and alleviate the viral load on the servers.  In this paper, we propose a new efficient caching strategy for the Named Data Networking architecture NDN named NECS which is the most promising architecture between all the ICN architectures. The proposed strategy reduces the traffic redundancy, eliminates the useless replication of contents and improves the replay time for users due to the strategic position of cache routers. Besides, we evaluate the performance of this proposed strategy and we compare it with three other NDN caching strategies, using the simulator network environment NdnSIM. On the basis of the simulations carried out, we obtained interesting and convincing results.
Scalability of Mobile Cloud Storage
Authors: Hussien Nur Syahela , Sulaiman Sarina , Aborujilah Abdulaziz , Wibowo Merlinda , Samma Hussein
Published: November 2021

Today, there are high demands on Mobile Cloud Storage (MCS) services that need to manage the increasing number of works with stable performance. This situation brings a challenge for data management systems because when the number of works increased MCS needs to manage the data wisely to avoid latency occur. If latency occurs it will slow down the data performance and it should avoid that problem when using MCS. Moreover, MCS should provide users access to data faster and correctly. Hence, the research focuses on the scalability of mobile cloud data storage management, which is study the scalable on how deep the data folder itself that increase the number of works.
Adenocarcinoma lung presenting with meningeal carcinomatosis
Authors: Dixit Ramakant , Goyal Mukesh , Nowal Paras , Indushekhar Varna
Published: November 2021

Meningeal infiltration by malignant metastasis process without brain parenchymal involvement is very unusual event in patients with bronchogenic carcinoma. This manuscript describes a case of adenocarcinoma right lung in a 48-year old male having persistent headache. The cerebrospinal fluid cytology revealed the presence of metastatic deposits of adenocarcinoma lung that confirmed the diagnosis of meningeal carcinomatosis.
Pulmonary actinomycosis: cytomorphological features
Authors: Martínez-Girón Rafael , Pantanowitz Liron
Published: November 2021

Pulmonary actinomycosis is an uncommon infectious disease. Although the gold standard for diagnosis is histological examination with bacterial culture of lung tissue, cytology samples offer a fast and low-cost alternate diagnostic procedure. The cytology literature on this topic is limited to mostly case reports. Therefore, the aim of this study was to review cytological material in a series of patients with a diagnosis of pulmonary actinomycosis to characterize the main cytomorphological findings.  Different cytological respiratory samples including sputum smears, bronchoalveolar lavages (BALs), transthoracic or endobronchial fine needle aspiration cytology (FNAC) and cell block preparations were used for retrospective examination. For all cases patient age, gender, symptoms, and radiological chest findings were recorded. A total of 26 cytological respiratory samples (14 sputum smears, 9 FNAC, two BALs) including direct smears and 6 cell blocks from 9 patients were examined. In sputum smears the most remarkable findings were the presence of dark cotton ball masses with projections like spider legs and/or mouse tails (75% of the samples). Sulfur granules were observed in 4 (40%) of the sputum smears and within FNAC cases. Various respiratory cytology samples including sputum smears, FNAC and BALs can reveal cytomorphological findings diagnostic of pulmonary actinomycosis. Characteristic cytological findings compatible with a diagnosis of this infection include cotton ball masses and less frequently sulfur granules.
Editorial
Authors: D. L. E.
Published: November 2021

No abstract available.
Rehabilitation of the Amputee
Authors: Kaplan C. J.
Published: November 2021

No abstract available.
Book Reviews
Authors: D. L. E.
Published: November 2021

No abstract available.
Dr. H. Haden
Authors: Office Editorial
Published: November 2021

No abstract available.
Some impressions of the World Confederation for Physical Therapy
Authors: De Bruin Freda
Published: November 2021

No abstract available.
Recent advances in physiotherapeutical methods
Authors: Beaumont William
Published: November 2021

No abstract available.