bluuebunny/crossref_metadata_2025 huggingface dataset:
Kualitas Hidup Balita Stunted
Authors: Hendrawati Sri , Mediani Henny Suzana , Salsabila Nada Shofi
Published: May 2023

ABSTRACT The incidence of stunting in Indonesia is now a major nutritional problem. Stunted state is the beginning of the occurrence of stunting in children and allows influence also on the quality of life of children. This study aimed to see a picture of the quality of life of stunted toddlers. This research design used quantitative descriptive research. The population to be studied were all children with stunting aged 2-5 years in the Banjaran Community Health Center working area, Bandung Regency. The sampling technique used in this study was total sampling with a sample of 151 children. Assessment of the quality of life of stunted children was measured using the PedsQLTM 4.0 Generic Core Scales Proxy Parent Report instrument from Varni. Analysis of the data used in this study was univariate analysis using the mean value. The results of this study indicated that stunted children aged 2-5 years have a good quality of life of 59.6% and bad as much as 40.4%. The mean value of the whole individual respondent was 83.2 that was still poor value will be at risk of causing stunted children to become stunted. The conclusion from this study was that the average quality of life of stunted toddlers was good, but the quality of life of stunted toddlers was not necessarily good either. It was expected that parents and health workers can maintain the quality of life of these toddlers who were already good to stay good or even improve by making efforts to prevent stunting. Keywords: Quality of Life, Stunted, Toddler.  ABSTRAK Kejadian stunting di Indonesia kini menjadi permasalahan gizi utama. Keadaan stunted merupakan awal dari kejadian stunting pada anak dan memungkinkan berpengaruh juga terhadap kualitas hidup anak. Penelitian ini bertujuan untuk melihat gambaran kualitas hidup balita yang mengalami stunted. Rancangan penelitian ini menggunakan penelitian deskriptif kuantitatif. Populasi yang akan diteliti adalah semua anak penderita stunting usia 2-5 tahun di Wilayah Kerja Puskesmas Banjaran Kota Kabupaten Bandung. Teknik sampling yang digunakan dalam penelitian ini adalah total sampling dengan jumlah sampel 151 anak. Penilaian kualitas hidup anak stunted diukur menggunakan instrumen PedsQLTM 4.0 Generic Core Scales Proxy Parent Report dari Varni. Analisis data yang digunakan dalam penelitian ini adalah analisis univariat dengan menggunakan nilai mean. Hasil penelitian ini menunjukkan bahwa balita stunted usia 2-5 tahun memiliki kualitas hidup baik sebanyak 59,6% dan buruk sebanyak 40,4%. Nilai mean dari keseluruhan individu responden adalah 83,2 nilai yang masih buruk ini akan berisiko menyebabkan balita stunted menjadi stunting. Simpulan dari penelitian ini adalah rata-rata kualitas hidup balita stunted baik, namun kualitas hidup balita stunting belum tentu baik juga. Diharapkan orang tua dan tenaga kesehatan dapat menjaga kualitas hidup balita yang sudah baik ini agar tetap baik atau bahkan meningkat dengan melakukan upaya penyuluhan untuk pencegahan stunting. Kata Kunci: Balita, Kualitas Hidup, Stunted.
Comparison of Neutralizing Sars Cov-2 Igg Antibody Levels in Hospitalized Patients at Dr. Mohammad Hoesin Palembang Hospital
Authors: Ahmad Zen , Sudarto Sudarto , Linda Ra , PP Rouly , FR Alif , Rasyidi Syafran , Liana Phey
Published: May 2023

ABSTRACT COVID-19 is an acute respiratory disease that spreads rapidly throughout the world caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Published research on levels of SARS-CoV-2 antibodies in hospitalized COVID-19 patients is still limited. Research on sero-epidemiology and its correlation with the clinical severity of COVID-19 is needed as a database for pandemic governance, especially research on neutralizing antibodies. This study was designed to compare the levels of IgG SARS CoV-2 on the tenth day in hospitalized patients with various clinical severity at RSUP Dr. Mohammad Hoesin Palembang. This research is an observational-analytic study with a cross-sectional design. The study was conducted in the COVID-19 isolation ward of RSMH Palembang from December 2021 to March 2022. IgG SARS CoV-2 level was measured in patients with confirmed COVID-19. Differences in IgG values of SARS CoV-2 were tested with the Mann Whitney test. The effect of various confounding variables in this study was tested using bivariate and multivariate tests in the form of a chi-square test and multiple linear regression on the scale of the dependent variable. The study included 50 patients, consisting of 22 patients with mild-moderate severity and 28 patients with severely-critically ill. Bivariate analysis showed there was no significant difference of IgG SARS-CoV-2 between two groups. From the data analysis using the ROC curve, the cut-off point for SARS-CoV-2 IgG levels in predicting the severity of COVID-19 disease was 500 AU/mL. IgG SARS-CoV-2 level of more than 500 AU/mL causes an increased risk of 3.69 (95% CI 1.13-11.98) times to suffer from severe-critical COVID-19. Serum IgG SARS-CoV-2 levels were found to be significantly higher in patients with severe-critical symptoms than patients with mild-moderate symptoms in COVID-19 hospitalized patients at Dr. Mohammad Hoesin Palembang hospital. Keywords: COVID-19, severity of COVID-19, IgG SARS-CoV-2
Hubungan Pola Asuh Orang Tua terhadap Kejadian Stunting pada Balita
Authors: Fauziyah Nurul Azmi , Rosidin Udin , Purnama Dadang , Mardiah Wiwi , Susanti Raini Diah , Rahayuwati Laili
Published: May 2023

ABSTRACT Stunting caused by several interrelated factors. The risk factors for stunting consist of direct and indirect factors. One of the indirect risk factors is parenting. Parenting plays an important role in minimizing the two main factors that cause stunting, infection and poor food intake. Based on researchers initial observations, according to Sukamulya Village cadres, parenting patterns in Sukamulya Village was quite good. However, the prevalence of toddler stunting reaches 35.9%. The purpose of this study is to determine the relationship between parenting patterns and the incidence of stunting in toddlers. This study uses a correlational quantitative design with a cross-sectional approach. The population of this research is 96 people in Sukamulya Village who have toddlers and the sampling selected by total sampling technique. Data were analyzed univariate and bivariate using Chi-Square test. The results showed that 22 of 96 or 22.9% parents had bad parenting and 31 of 96 or 32.3% toddlers is stunting. The results of the correlation test between the two variables showed a p-value=0.043. There is a relationship between parenting patterns and the incidence of stunting in toddlers. Researchers recommend to make parenting pattern a point of concern in resolvinng stunting. Keywords: Parenting, Stunting, Toddlers  ABSTRAK Stunting disebabkan oleh faktor-faktor yang saling berhubungan. Faktor risiko stunting terdiri dari faktor risiko langsung dan tidak langsung. Salah satu faktor risiko tidak langsung stunting adalah pola asuh. Pola asuh berperan penting dalam meminimalisir dua faktor utama yang menyebabkan stunting, yakni infeksi dan asupan makanan yang buruk. Berdasarkan pengamatan awal, menurut kader Desa Sukamulya, pola asuh yang diberikan oleh orangtua di Desa Sukamulya tergolong cukup baik. Namun, angka prevalensi balita stuntingnya mencapai 35.9%. Penelitian ini bertujuan untuk mengetahui hubungan pola asuh orangtua terhadap kejadian stunting pada balita. Penelitian ini menggunakan desain kuantitatif korelasional dengan pendekatan cross-sectional. Populasi dari penelitian ini adalah 96 masyarakat Desa Sukamulya yang memiliki balita dan sampel diambil dengan teknik total sampling. Analisa data dilakukan secara univariat dan bivariat menggunakan uji Chi-Square. Hasil penelitian menunjukkan bahwa 22 dari 96 atau sebanyak 22,9% orangtua memiliki pola asuh yang buruk dan 31 dari 96 atau 32,3% balita mengalami stunting. Hasil uji korelasi antar kedua variabel menunjukkan nilai p value 0,043. Terdapat hubungan antara pola asuh orangtua dengan kejadian stunting pada balita. Peneliti memberikan rekomendasi untuk menjadikan pola asuh sebagai salah satu titik perhatian dalam penanggulangan stunting. Kata Kunci: Pola Asuh, Stunting, Balita
Pengaruh Perawatan Metode Kanguru terhadap Penurunan Tingkat Kecemasan Ibu Pasca Bersalin di RSU Royal Prima Medan
Authors: Laia Masrince , Hanum Parida , Lubis Wilda Sri Devi
Published: May 2023

ABSTRACT     LBW babies who are not cared for in the same room or separated from their mothers may cause stress to the mother about worrying about the baby's condition. Kangoroo mother care is an intervention in which mothers and babies are treated in the same room in order to meet the basic needs of babies such as warmth, breastfeeding, prevention from infection, as well as developmental stimulation, safety, affection, this can help the general condition get better. The purpose of this study was to determine the effect of kangaroo mother care on postpartum maternal anxiety. This type of study is quantitative research that uses a pre-test and posttest one group design with a Quasi Experimental design without a control group. Data were collected using the Zung Self-Rating Anxiety Scale questionnaire. The statistical test used is the Wilcoxon Signed Rank Test. The results showed that after being given kangaroo method treatment there was a decrease in anxiety levels (P value = <0.000), namely 17 people (61%) did not experience anxiety and11 people (39%) were in the mild anxiety category. Based on the research that has been carried out, it can be concluded that there is a difference in the anxiety level of respondents before kangaroo method treatment and after kangaroo method treatment, namely a decrease in anxiety levels in postpartum mothers with LBW babies. Keywords: Kangaroo mother care, LBW, Postpartum, Level of Anxiety  ABSTRAK Bayi dengan BBLR yang dirawat tidak satu ruangan atau terpisah dengan ibunya dapat menyebabkan stres pada ibu tentang khawatir akan kondisi bayinya. PMK merupakan salah satu intervensi dengan cara ibu dan bayi di rawat di ruang yang sama agar dapat memenuhi kebutuhan bayi yang mendasar seperti kehangatan, pemberian ASI, pencegahan dari infeksi, serta stimulasi perkembangan,keselamatan,kasih sayang, ini dapat membantu keadaan umum menjadi lebih baik.  Penelitian ini untuk mengetahui pengaruh PMK terhadap kecemasan ibu pasca bersalin. Dalam membuat penelitian ini menggunakan penelitian kuantitatif yang menggunakan rancangan pre-test dan posttest one group design, dengan rancangan Quasi Eksperimental tanpa kelompok control. Pengumpulan data menggunakan lembar kuesioner Zung Self-Rating Anxiety Scale. Uji statistik yang digunakan adalah Wilcoxon Signed Rank Test. Hasil pengukuran menunjukkan bahwa setelah diberikan perawatan metode kanguru terdapat penurunan tingkat kecemasan (P value = <0.000) yaitu sebanyak 17 orang (61%) tidak mengalami cemas dan 11 orang (39%) berada pada kategori kecemasan ringan. Berdasarkan penelitian yang telah dilaksanakan maka didapatkan kesimpulan bahwa terdapat perbedaan dari tingkat kecemasan responden sebelum perawatan metode kanguru dan sesudah perawatan metode kanguru yaitu terjadi penurunan tingkat kecemasan pada ibu pascabersalin dengan bayi BBLR. Kata Kunci: Perawatan Metode Kanguru, BBLR, Pascapersalinan, Tingkat Kecemasan
Development of Structural Damage Detection Method Working with Contaminated Vibration Data via Autoencoder and Gradient Boosting
Authors: Dang Viet-Hung
Published: May 2023

Vibration-based structural damage detection is one of the most promising venues for building smart and automated structural health monitoring applications; however, its applicability is impeded by a large amount of collected vibration data, and the performance could be undermined by degraded data. Therefore, this study develops a robust framework, dubbed AutoBoost-SDD, that can effectively handle contaminated vibration data and provide reliable monitoring results within reasonable computational resources. The proposed method consists of three key components. Firstly, multi-domain feature extraction techniques are utilized to convert high-dimensional raw data into informative feature vectors. Secondly, the auto-encoder deep learning architecture is leveraged to refine feature vectors of contaminated data. Finally, a tree-based boosting machine learning algorithm, namely LightGBM, is employed to assess the structures’ operational states using learned output from the second step. The viability and performance of the proposed framework are illustrated via three case studies involving numerical data of a 5-degree of freedom system, a 2D frame structure, and experimental data of a large-scale 18-story frame structure from the literature. The results show that the AutoBoost-SDD framework is able to provide reasonable detection results despite the presence of various contaminations, including noisy, missing, and anomalous data.
«Я БУВ ГІРШЕ НІЖ СОБАКА І ВЕСЬ ЧАС ПИТАВ ЧОМУ ТАК»: СТАНОВИЩЕ ЄВРЕЇВ У МІЗОЧІ ПІД ЧАС ГОЛОКОСТУ
Authors: Михальчук Роман
Published: May 2023

Метою статті є аналіз становища євреїв під час Голокосту на прикладі волинського містечка Мізоч. На основі історіографічного та джерелознавчого доробку відтворити поневіряння та умови життя мізоцьких євреїв в 1941–1942 рр. «Вирішення єврейського питання» передбачало не лише вбивство жертв, а й їхнє особливе правове становище. Заходи примусової реєстрації, ідентифікації, носіння спеціальних позначок, сегрегації в гетто, обмеження в продуктах харчування, пересування тощо перетворювали їх в об’єкт принижень та створювали ґрунт для подальших переслідувань.

Традиційні ролі євреїв під час Голокосту змінювалися. У гетто часто діти ставали постачальниками продуктів в сім’ю, маючи можливість контактувати з неєврейськими жителями на «арійській» стороні, працюючи в них. Праця в містечку та поза ним була не лише виснажливою, а й становила небезпеку для життя. На примусових роботах у Здолбунові мізоцькі євреї потерпали від нестерпних умов, голоду, побиття. Інколи свавілля наглядачів призводило до смерті робітників. Грабунок євреїв став одним із засобів позбавлення умов для існування, адже це унеможливало підтримувати своє життя. Під час погрому в Мізочі було не лише пограбовано євреїв, а й зафіксовано випадки вбивства та зґвалтувань. Найбільш тісно з євреями контактували місцеві поліцейські, які використали свої посади для власного матеріального збагачення.

Заходи упослідження жертв Голокосту окупантами впливали на ставлення до них з боку неєврейських жителів. У розпалюванні ворожнечі відіграла свою роль преса, яка звинувачувала мізочан за «безмірну любов до жидівства». Євреїв перетворено на соціальних ізгоїв, тому вони перебували поза межами суспільної ієрархії. У системі нацистського геноциду протистояти такій політиці не було можливості.
БАБИН ЯР СЕРГІЯ ЛОЗНИЦІ. УКРАЇНСЬКИЙ КОНТЕКСТ
Authors: Козленко Іван
Published: May 2023

Прем’єра «Бабин Яр. Контекст» відбулась в Україні в рамках відзначення 80-річчя трагедії Бабиного Яру. Після кінотеатральної прем’єри фільм показали на одному з центральних телеканалів з охопленням аудиторії в 5 млн. глядачів. Частина української інтелігенції назвала фільм тенденційним, таким, що висвітлює історію Бабиного Яру однобоко й має за мету скомпрометувати українців, однобоко показавши їх антисемітами та колаборантами. В дискусії, що відбулась після ефіру за участі українських науковців,  філософ Вахтанг Кебуладзе зокрема висловив думку про те, що в фільмі відтворено радянський наратив про початок війни в 1941 році, а Україну наділено політичною суб’єктністю, якої вона насправді в висвітлюваний період не мала.

«Бабин Яр. Контекст» став елементом національної дискусії про спосіб комеморації жертв Голокосту в Україні, роль і місце в цьому процесі Меморіалу Бабин Яр. Він реактуалізував страхи частини української інтелігенції щодо імовірної інструменталізації Росією теми Голокосту як елемента гібридної війни, наміру роздмухати війну пам’ятей та підважити історичні та моральні засади існування незалежної української держави. Авторське висловлювання Лозниці в «Бабин Яр. Контекст» було сприйнято частиною української гуманітарної спільноти як таке, що розвиває радянські та російські історичні наративи.
Tác động của năng lực cạnh tranh và phát triển ứng dụng công nghệ thông tin – truyền thông đến ổn định tài chính ngân hàng thương mại Việt Nam
Authors: Phạm Thủy Tú , Đào Lê Kiều Oanh , Đặng Nguyễn Phương Thảo
Published: May 2023

Trong nghiên cứu mối quan hệ tác động của năng lực cạnh tranh và mức độ phát triển ứng dụng công nghệ thông tin – truyền thông đến ổn định tài chính ngân hàng, bài viết sử dụng chỉ số ICT, Lerner và Zscore đo lường mức độ ứng dụng Công nghệ thông tin - Truyền thông, năng lực cạnh tranh và ổn định tài chính của ngân hàng. Nghiên cứu thực hiện trên dữ liệu 30 ngân hàng thương mại Việt Nam. Kết quả cho thấy năng lực cạnh tranh và ứng dụng Công nghệ thông tin - Truyền thông góp phần thúc đẩy ổn định tài chính của các ngân hàng. Đồng thời tìm thấy bằng chứng về mối quan hệ tương tác giữa Lerner và ICT trong giai đoạn vừa qua tác động ngược chiều với ổn định tài chính ngân hàng. Hàm ý rằng khi áp lực cạnh tranh giữa các ngân hàng tăng, việc tăng cường đầu tư phát triển Công nghệ thông tin - Truyền thông trong giai đoạn vừa qua chưa hiệu quả, gây bất ổn tài chính. Từ đó, chúng tôi đề xuất một số hàm ý chính sách.
II Jornadas de Ciencia y Tecnología - II Encuentro de investigadores en formación
Authors: Mar del Plata UTN Facultad Regional
Published: May 2023

El presente volumen comprende las contribuciones presentadas en las II Jornadas de Ciencia y Tecnología y II Encuentro de Investigadores en formación realizadas en la Facultad Regional Mar del Plata de la Universidad Tecnológica Nacional el 17 de noviembre de 2022. Estas contribuciones son producto de la labor desarrollada en los proyectos de investigación y se inscriben en el objetivo propuesto en la edición anterior de las Jornadas respecto de construir un espacio de difusión para los aportes teóricos y empíricos de los investigadores, en formación y formados, y de las cátedras, ante los desafíos de la comunidad local y regional. Los trabajos expuestos referidos al sector naval, pesquero-acuícola y ambiental se proponen contribuir al bienestar de la comunidad, en un recorrido que comprende dos conferencias magistrales de investigadores pertenecientes a Facultades Regionales que dictan carreras homónimas a las nuestras y trece trabajos cuya autoría corresponde a investigadores de la sede que comparten como eje común en sus estudios, la provisión de soluciones tecnológicas ante los desafíos sociales, económicos, culturales y ambientales del territorio donde se asientan estas producciones.
MIEMBROS DEL COMITÉ ORGANIZADORPresidente: Ing. Fernando ScholtusIntegrantes:Esp. Beatriz LupínMg. Néstor Machado SusseretDra. Marina MaggioreDr. Sebastián Ortiz MirandaDra. Yamila RodríguezDra. Alicia Zanfrillo
MIEMBROS DEL COMITÉ CIENTÍFICODr. Juan Ignacio ArdhenghiLic. Cecilia CastañosDr. Gustavo CarrMg. Nancy FigueroaDr. Eduardo HowardEsp. Beatriz LupínDra. Marina MaggioreDr. Sebastián OrtizDra. Nair de los Ángeles PereiraDra. Yamila RodríguezDr. Martín SequeiraDr. Santiago UrquizaDra. Marta VidalDr. Gerardo WadelDra. Alicia Zanfrillo
Enhanced Diffusion and Confusion Based Encryption Algorithm Using Differential Evolution and Chaotic Mapping
Authors: Doğan Musa , Doğan Nurettin
Published: May 2023

Encryption is critical to protecting sensitive data, especially images, against potential illegal access and breaches. The use of chaotic maps for image encryption is widespread among researchers. However, it is necessary to set up initial parameters for chaotic maps to generate random sequences. These parameters need to be selected with care. To determine the optimal initial parameters for image encryption, evolutionary optimization techniques have been used. In this paper, we propose a secure image-based communication system based on an optimized image encryption algorithm. This approach uses differential evolution optimization, which is an ideal solution for reducing convergence time when optimizing chaotic map parameters. Furthermore, the security parameters of these techniques are evaluated, including entropy, Number of Pixel Change Rate (NPCR), Unified Average Changed Intensity (UACI), and correlation coefficients. The simulation results of the proposed encryption approach by combining Arnold’s cat map, chaotic logistic map and optimization method show that the encrypted image is safe against attacks.
The role of dialogue in meaningful classroom interaction in South Africa
Authors: Steinke Dr Kellie , Wildsmith-Cromarty Prof Rosemary
Published: May 2023

The importance of meaningful classroom dialogue in the foundation and early intermediate levels of education in creating effective literacy skills is well documented.  Despite comments in a recent paper that there is a dearth of research on classroom observations around print in South Africa since 1994 at foundation level, there have actually been several studies that have observed classroom practice in this area post-1994. This paper discusses three particularly important ones that spanned some three decades in South Africa and observed the role and practice of dialogue in classroom teaching around text at foundation and early intermediate schooling levels.  All three studies indicate that teaching styles have changed very little to date, and that meaningful classroom interaction between teacher and learner remains largely absent.  The Pedagogical Content Knowledge (PCK) of the participating teachers continues to restrict student agency in the area of classroom interaction.  Although each of the researchers captured the evidence in different ways, they all came to the same conclusion: that all teachers are still teaching restrictively and do not ask the type of open, extended questions necessary to engage in dialogue which helps develop critical thinking or the vocabulary necessary to develop effective literacy skills in learners.
Environmental Engagement in Higher Education Institutions
Authors: D. Manalo Hernani , T. Manalo Ma Riza
Published: May 2023

Higher Education Institutions (HEIs) are the potential stewards of the environment. Their influence extends from the workplace to the communities and homes where they play a vital role in environmental engagement. Hence, this paper investigates the 3 drivers of environmental engagement, namely, Knowledge and Awareness (KA), Personal Engagement (PE), and Policies and Practices (PP) in Environmental Engagement (EE) of the 213 faculty of the 9 HEIs in the Philippines. The study used a Quantitative Approach employing the comparative and correlational analyses of the survey results derived from the duly validated instruments. Pearson Product Moment Correlation test shows that the Knowledge and Awareness (KA) driver has no relationship while Personal Engagement (PE), and Policies and Practices (PP) have a significant relationship with Environmental Engagement (EE). The consistency of the faculty's Environmental Engagement at home and at work, as supported by the Behavior Consistency Theory, prevails over Knowledge and Awareness. The faculty's Environmental Engagement is high in the tasks with tangible economic value such as energy and water conservation but low in those with intangible benefits like recycling or waste segregation. While the Policies and Practices driver is significantly related to Environmental Engagement, less than half of the faculty are engaged in training, campaign, and policy participation. Thus, the study recommends incentivizing faculty Environmental Engagement and needs assessment for environmental learning and development programs. The study offers a valuable contribution to the latent literature on Environmental Engagement in Higher Education.
Avaliação da Microscopia Virtual como ferramenta do ensino da histopatologia por estudantes da graduação saúde
Authors: Fonseca Luiz Carlos Machado da , Prestes Pietra Bezerra , Borba Maria Clara Carvalho , Corrêa Sabrina Elora de Almeida , Lasmar Michella Lima
Published: May 2023

A popularização da internet possibilitou às novas tecnologias um papel mais significativo na educação. Nesse contexto, o estudo da histopatologia está inserido nesse processo através da criação de algumas ferramentas como a Microscopia Virtual (MV). A MV consiste na utilização de lâminas histopatológicas digitalizadas a partir de amostras em lâminas de vidro. O objetivo geral do estudo foi avaliar a percepção dos alunos de medicina e odontologia de uma instituição pública de ensino em relação à utilização da MV no ensino da histopatologia. Trata-se de um estudo de corte transversal de análise descritiva prospectiva quanti-qualitativo. Os estudantes foram convidados a participar da pesquisa e após concordarem com o Termo de Consentimento Livre e Esclarecido, responderam um questionário eletrônico, em escala Likert, com perguntas relacionadas à experiência prévia em outras disciplinas com uso do microscópio de luz e sobre o uso atual da Microscopia Virtual (MV), respectivamente. Baseando-se nos dados obtidos e em concordância com outros estudos, constatou-se preferência pela MV, com médias significativamente maiores em quase todos os itens. Em síntese, observa-se que a MV é uma ferramenta viável de ensino da histopatologia e pode se apresentar com caráter substituto ou complementar em relação ao método tradicional.
Avaliação do impacto do curso de eletrocardiograma para técnicos de enfermagem
Authors: Santos Camila Marques dos , Kobayashi Rika Miyahara , Simonetti Sérgio Henrique
Published: May 2023

Introdução: O técnico de enfermagem presta assistência aos pacientes graves e, portanto, requer o conhecimento sobre traçado eletrocardiográfico e suas alterações. Estudos mostram que há lacunas no conhecimento do enfermeiro e do técnico de enfermagem acerca do exame eletrocardiográfico e que a educação permanente é uma importante estratégia na melhoria do conhecimento destes profissionais. Objetivos: Construir e implementar um curso remoto de traçado eletrocardiográfico para técnico de enfermagem e avaliar o conhecimento e atuação do profissional pré e pós curso. Método: Trata-se de um estudo exploratório-descritivo e de intervenção educativa, com abordagem quantitativa junto a uma amostra de 21 profissionais que participaram do curso no período entre abril a setembro de 2022. Resultados: Foi criado um curso modular de traçado eletrocardiográfico incluindo atividades pré e pós-curso para avaliar o conhecimento do técnico de enfermagem e houve melhora de 7,2% no conhecimento no período pós-curso. Conclusão: A partir da construção do curso e sua implementação, verificou-se melhora no conhecimento do técnico de enfermagem, entretanto são necessários investimentos para sua participação em pesquisa, na infraestrutura institucional para viabilizar os processos educativos dos técnicos de enfermagem mediado por tecnologias, considerando sua inclusão digital.
(In)segurança na perda não programada de Cateter Nasoenteral em unidades clínicas – danos éticos e financeiros
Authors: Lemos Laurine Mendes Belarmino , Costa Cristiane Maria Amorim , Marta Cristiano Bertolossi , Oliveira Elson Santos de , Peres Ellen Marcia , Silva Roberto Carlos Lyra da , Dias Dayse da Silva Farias
Published: May 2023

Este estudo teve por objetivo analisar a relação custo- qualidade do cuidado relacionado à prática de inserção cateter nasoenteral. Trata-se de um estudo descritivo, quantitativo-qualitativo, que teve como cenário um Hospital público localizado no Estado do Rio de Janeiro. A Coleta de dados foi realizada pela residente responsável por essa pesquisa e por mais duas pesquisadoras residentes, através de entrevistas semi-estruturadas com perguntas abertas e fechadas, abordando questões específicas sobre a inserção da sonda nasoenteral, a vivência hospitalar acerca do tema, seu conhecimento e sua capacidade de reflexão. O Enfermeiro é um profissional com capacidade técnica, e conhecimento teórico suficiente para perceber quando um procedimento não é necessário para o paciente, além disso, a prática de realizar execução de prescrição às cegas que porventura ocasione dano ao paciente, é passível de punição e fere o objetivo da segurança do paciente. Além disso, mesmo que o procedimento não ocasione dano físico, a ética nos permite entender que há dano psicológico ao paciente, e consequentemente há crime. Foi identificada a necessidade de investimento em capacitação voltados para os cuidados indispensáveis ao procedimento de inserção e manutenção de SNE com o objetivo de munir seus profissionais de conhecimentos significativos para que através dessa intervenção obtenha-se uma redução de custo financeiro.
EVALUATION OF USER SATISFACTION USING THE PIECES FRAMEWORK IN THE TEMAN BUS APPLICATION
Authors: Arakian Laurensia Anjelina Tutosili , Darmawiguna I Gede Mahendra , Indradewi I Gusti Ayu Agung Diatri
Published: May 2023

The TEMAN BUS program employs technology to improve road-based public transportation in urban areas. The Ministry of Transportation of the Republic of Indonesia implements digital transformation by developing the TEMAN BUS application to support TEMAN BUS transportation services. Passengers will find it more straightforward with this application to access the TEMAN BUS travel route, view information about the departure timetable, and observe bus arrivals in real time. To evaluate an application's effectiveness, it is necessary to assess the user's impression when the program is launched. This study uses the PIECES Framework, which has six variables Performance, Information, Economics, Control and Security, Efficiency, and Service, to assess how users perceive the TEMAN BUS application. The findings of this study were derived from the perceptions of respondents, who felt that information and data performance, control and security, service, and user satisfaction were not good, and from the findings of hypothesis testing, which suggested that information and data performance and user satisfaction were unrelated.
Multi-text reading strategy for teaching and effectiveness evaluation
Authors:   Center for General Education, National Taichung University of Science and Technology, Taichung, Taiwan., Lin Yen-Ling , Huang Cheng-Chih ,   Center for General Education, National Taichung University of Science and Technology, Taichung, Taiwan.
Published: May 2023

In this study, the concept of group co-learning and multi-text reading was incorporated into the teaching of Mandarin language in the second year of a Five-year Junior College Program, and attempts were made to create a co-learning environment, design learning courses and reading and writing activities to develop and enhance students’ basic self-learning (reading and writing) skills. The teaching effectiveness was examined by testing and questionnaire feedback. In addition to comparing the results before and after teaching by the pre- and post-tests of the National College Language Proficiency Test, organized by the National Taichung University of Education, the study also used the learning feedback questionnaire to examine whether the teaching strategies were accepted by the students. The results showed that the change in the teaching strategy of Taiwanese Mandarin in the second year of Five-year Junior College Program was effective in enhancing students’ reading initiative and writing achievement, as well as in building an acceptable learning identity. Keywords: Taiwanese Mandarin, teaching, five-year junior college program, learning community, flipped teaching, reading skill, reading instruction.
Impact of fatty liver on long-term outcomes in chronic hepatitis B: a systematic review and matched analysis of individual patient data meta-analysis
Authors: Wong Yu Jun , Nguyen Vy H. , Yang Hwai-I , Li Jie , Le Michael Huan , Wu Wan-Jung , Han Nicole Xinrong , Fong Khi Yung , Chen Elizebeth , Wong Connie , Rui Fajuan , Xu Xiaoming , Xue Qi , Hu Xin Yu , Leow Wei Qiang , Goh George Boon-Bee , Cheung Ramsey , Wong Grace , Wong Vincent Wai-Sun , Yu Ming-Whei , Nguyen Mindie H.
Published: May 2023

Background/Aims: Chronic hepatitis B (CHB) and fatty liver (FL) often co-exist, but natural history data of this dual condition (CHB-FL) are sparse. Via a systematic review, conventional meta-analysis (MA) and individual patient-level data MA (IPDMA), we compared liver-related outcomes and mortality between CHB-FL and CHB-no FL patients.Methods: We searched 4 databases from inception to December 2021 and pooled study-level estimates using a random- effects model for conventional MA. For IPDMA, we evaluated outcomes after balancing the two study groups with inverse probability treatment weighting (IPTW) on age, sex, cirrhosis, diabetes, ALT, HBeAg, HBV DNA, and antiviral treatment.Results: We screened 2,157 articles and included 19 eligible studies (17,955 patients: 11,908 CHB-no FL; 6,047 CHB-FL) in conventional MA, which found severe heterogeneity (I2=88–95%) and no significant differences in HCC, cirrhosis, mortality, or HBsAg seroclearance incidence (P=0.27–0.93). IPDMA included 13,262 patients: 8,625 CHB-no FL and 4,637 CHB-FL patients who differed in several characteristics. The IPTW cohort included 6,955 CHB-no FL and 3,346 CHB-FL well-matched patients. CHB-FL patients (vs. CHB-no FL) had significantly lower HCC, cirrhosis, mortality and higher HBsAg seroclearance incidence (all p≤0.002), with consistent results in subgroups. CHB-FL diagnosed by liver biopsy had a higher 10-year cumulative HCC incidence than CHB-FL diagnosed with non-invasive methods (63.6% vs. 4.3%, p<0.0001).Conclusions: IPDMA data with well-matched CHB patient groups showed that FL (vs. no FL) was associated with significantly lower HCC, cirrhosis, and mortality risk and higher HBsAg seroclearance probability.
Revealing host-pathogen interactions via receptor-binding using tissue microarrays
Authors:   , Nemanichvili Nikoloz
Published: May 2023

The binding of a viral pathogen to the host cell is the first, crucial, step of infection. This first step in host-pathogen interactions is dependent on the attachment tools of the viral pathogen and the presentation of attachment factors by the host. Pathogen receptor specificity and host receptor distribution govern which cells and tissues are susceptible, known as host tropism. Using our own developed tissue microarrays to represent the host and the viral attachment proteins to represent the pathogen, we set out to study how receptor-binding interactions can improve our understanding of receptor distribution of both domestic and wild animals and how glycobiology plays a key role in driving these receptor-binding interactions. We used these tools to study and map the receptor binding of influenza A & D attachment proteins in respiratory tissues of various domesticated and wild animals. Receptor binding is the first step in infection and it is therefore of high importance to study it. The use of tissue microarrays is a great in-between system for studying the distribution of these host receptors. The system does have its shortcomings, particularly in terms of glycolipid and mucin detection. To summarize, TMAs are not a replacement for current methods used, such as glycan arrays and animal experiments, but are an excellent addition that complements those systems for studying receptor interactions.
Innovative drug monitoring of factor VIII and emicizumab in haemophilia A
Authors:   , Donners Anouk Anna Maria Therese
Published: May 2023

People with haemophilia A (PwHA) have a deficiency of coagulation factor VIII and experience recurrent bleeding. Currently, PwHA are treated effectively with drugs such as FVIII products or emicizumab. Measuring and monitoring these drugs is important to determine the dose, which needs to be effective but not unnecessarily high due to costs (i.e., ~€100.000‒€400.000 per person per year). Mass-spectrometry (MS) is a beneficial technique to measure drug concentrations in blood and is used in clinical laboratories worldwide. Prior to this thesis, MS analysis was not used in haemophilia A care. This thesis aimed to optimize drug monitoring of FVIII and emicizumab in PwHA in three parts. Firstly, the development of MS methods measuring drugs similar to FVIII and emicizumab was summarized in a simple six-step workflow. Subsequently, two MS methods measuring FVIII and emicizumab were set-up and validated. Secondly, the studies on the concentration–biomarker relationship of FVIII yielded more questions than answers, while studies on literature and in our clinic indicated that emicizumab concentrations on standard dosing were often two-times above the minimal effective concentration. Thirdly, this thesis formed the groundwork for the design of a study protocol where the emicizumab dose is adjusted individually by targeting the minimum effective concentration. Finally, future perspectives were shared by giving four new applications of MS analysis quantifying FVIII and a framework for cost-efficient dosing strategies for other drugs similar to emicizumab.
Towards 3D fabrication of MgP-based mechanically competent implants for bone regeneration
Authors:   , Golafshan Nasim
Published: May 2023

The development of the degradable bone implants has gained a great attention
during the last years. This need comes from the fact that autologous bone
transplantation, which is the current standard and most effective treatment of bone
defects, is associated with severe drawbacks regarding donor site morbidity and
limited availability. However, there is a lack of synthetic materials that are degradable,
osteopromotive and mechanically competent at the same time. Further, materials
processing and the implantation of the scaffolds in the body are also an important
challenge. In this thesis, by using advanced 3D printing technologies, the fabrication
of biodegradable, patient-specific, and mechanically competent MgP-based implants
has been explored to treat critical-sized bone defects. The developed MgP-based
biomaterial is inspired by the composition of native bone tissue and can be degraded
in the body and subsequently be replaced by native bone.
Research on the construction of the party building function evaluation index system in NPOs
Authors: Fan Jiayao , Chen Zihao
Published: May 2023

With the deepening reform of the social system in China, NPOs, as the main body of social governance, play an important role in resolving social contradictions and maintaining social stability. In recent years, the party-building work of NPOs has been vigorously carried out. How to build the evaluation index system of the party-building function of NPOs, measuring the party-building function of NPOs, and exploring the factors affecting the function of party building is the key path to promoting the party-building function of NPOs. This paper summarizes the research status of NPOs’ party-building function and chooses the political guidance, communication, and coordination, development service as the three functional dimensions of building NPOs’ evaluation index system of party-building function. On this basis, the study will further explore the influencing factors of NPOs’ party-building function, laying a good foundation to establish the strengthening mechanism of NPOs’ party-building function, and putting forward optimization suggestions for improving NPOs’ party-building function.
Perancangan Sistem Informasi Administrasi Tugas Akhir (SIATA) Berbasis Web Pada PSDKU Politeknik Negeri Malang di Kota Kediri
Authors: Selvia Ferdiana Kusuma  , Muhammad Faizal Izak  , Herliana Adawiyyah  , Dika Andika
Published: May 2023

Penelitian ini merupakan penelitian perancangan sistem informasi administrasi tugas akhir berbasis web pada PSDKU POLINEMA di Kota Kediri dengan menggunakan model waterfall yang tahapannya terdiri dari analisis sistem, perancangan, pengkodean dan uji coba sistem. Penelitian ini bertujuan untuk mempercepat, mempermudah dan meningkatkan akurasi proses administrasi ujian tugas akhir yang sebelumnya masih dilakukan secara manual yaitu mengandalkan kertas sebagai dokumen utama, serta adanya komunikasi dan koordinasi yang masih dilakukan secara offline. Hal ini dapat mengakibatkan adanya tumpukan berkas pada ruangan, tentunya mengakibatkan kesulitan dalam pengelolaan berkas administrasi mahasiswa. Proses pengelolaan tentunya akan lebih menyita banyak waktu dan tenaga. Fitur pada sistem informasi yang disediakan meliputi upload file kelengkapan berkas, melakukan revisi secara online, kelola dosen pembimbing dan penguji serta penilaian oleh dosen pembimbing dan penguji dengan menerapkan sistem yang lebih terkomputerisasi dan tersusun secara sistematis. Berdasarkan uji coba yang telah dilakukan, sistem dapat berjalan sesuai dengan ketentuan dapat digunakan sebagai penunjang proses administrasi ujian tugas akhir dengan memperhatikan aspek efektifitas dan efisiensi waktu serta tempat.
Meningkatkan Minat Belajar dan Kreativitas Anak Panti Asuhan Puteri Aisyiyah Muhammadiyah Medan
Authors: Saputra Rizki , Siregar Hairani
Published: May 2023

Kegiatan dilakukan di Panti Asuhan Putri Aisyiyah Medan untuk mengkaji permasalahan yangdialami oleh anak yatim. Masalah yang dialami oleh anak panti asuhan adalah kurangnya pengetahuandasar anak tentang menulis, membaca dan berhitung. Banyaknya anak yatim piatu yang menggunakansmartphone untuk bermain game online dan menonton tiktok. Kegiatan ini memiliki tujuan untukmeningkatkan minat belajar dan kreativitas anak yatim piatu yang merupakan mini project tentang pendidikan untuk anak. Mitra kegiatn yang mengalami masalah ini. Mitra tersebut terdiri dari anak-anak yang masih duduk di bangku Sekolah Dasar (SD). Tahapan kelompok sosial diguanakan dalam penelitian ini, mulai dari tahap persiapan hingga tahap terminasi. Meningkatkan minat belajar pada anakmembutuhkan metode yang tepat agar anak nyaman dengan mini project yang telah dibuat. Metodeyang digunakan adalah metode Delphi dengan menggunakan kuesioner untuk menyimpulkanpermasalahan apa saja yang dimiliki oleh anak yatimDiharapkan anak-anak panti asuhan dapatmelanjutkan minat belajar dan mengasah kreativitasnya agar tidak mengalami kesulitan dalam belajardi sekolah
Review on Gamification in e-learning: Effects and Challenges
Authors: Senthil kumaran V  , Nithiya Shri M  , Harini A
Published: May 2023

Information technology has brought us a great deal of technological advancement, opening up endless possibilities for distance education. E-Learning platforms make it possible to connect people around the globe. Using the various technologies that are available, Gamification enhances the performance of e-learning platforms. Gamification of e-learning platforms helps in providing an engaging learning experience for users of all ages. Applying gamification in a non-gaming environment motivates students and also keeps them engaged in learning. This paper summarizes various game elements such as points, leader boards, badges, provided to the users for better e-learning experience by gamifying the environment and discussing the impact of gamification.
Strategies for surface coatings of implantable cardiac medical devices
Authors: Coronel-Meneses David , Sánchez-Trasviña Calef , Ratera Imma , Mayolo-Deloisa Karla
Published: May 2023

Cardiac medical devices (CMDs) are required when the patient’s cardiac capacity or activity is compromised. To guarantee its correct functionality, the building materials in the development of CMDs must focus on several fundamental properties such as strength, stiffness, rigidity, corrosion resistance, etc. The challenge is more significant because CMDs are generally built with at least one metallic and one polymeric part. However, not only the properties of the materials need to be taken into consideration. The biocompatibility of the materials represents one of the major causes of the success of CMDs in the short and long term. Otherwise, the material will lead to several problems of hemocompatibility (e.g., protein adsorption, platelet aggregation, thrombus formation, bacterial infection, and finally, the rejection of the CMDs). To enhance the hemocompatibility of selected materials, surface modification represents a suitable solution. The surface modification involves the attachment of chemical compounds or bioactive compounds to the surface of the material. These coatings interact with the blood and avoid hemocompatibility and infection issues. This work reviews two main topics: 1) the materials employed in developing CMDs and their key characteristics, and 2) the surface modifications reported in the literature, clinical trials, and those that have reached the market. With the aim of providing to the research community, considerations regarding the choice of materials for CMDs, together with the advantages and disadvantages of the surface modifications and the limitations of the studies performed.
Unlocking cellular barriers: silica nanoparticles and fullerenol conjugated cell-penetrating agents for enhanced intracellular drug delivery
Authors: Ravelo-Nieto Eduardo , Cifuentes Javier , Ruiz Puentes Paola , Rueda-Gensini Laura , Quezada Valentina , Ostos Carlos , Muñoz-Camargo Carolina , Reyes Luis H. , Duarte-Ruiz Alvaro , Cruz Juan C.
Published: May 2023

The limited delivery of cargoes at the cellular level is a significant challenge for therapeutic strategies due to the presence of numerous biological barriers. By immobilizing the Buforin II (BUF-II) peptide and the OmpA protein on magnetite nanoparticles, a new family of cell-penetrating nanobioconjugates was developed in a previous study. We propose in this study to extend this strategy to silica nanoparticles (SNPs) and silanized fullerenol (F) as nanostructured supports for conjugating these potent cell-penetrating agents. The same molecule conjugated to distinct nanomaterials may interact with subcellular compartments differently. On the obtained nanobioconjugates (OmpA-SNPs, BUF-II-PEG12-SNPs, OmpA-F, and BUF-II-PEG12-F), physicochemical characterization was performed to evaluate their properties and confirm the conjugation of these translocating agents on the nanomaterials. The biocompatibility, toxicity, and internalization capacity of nanobioconjugates in Vero cells and THP-1 cells were evaluated in vitro. Nanobioconjugates had a high internalization capacity in these cells without affecting their viability, according to the findings. In addition, the nanobioconjugates exhibited negligible hemolytic activity and a low tendency to induce platelet aggregation. In addition, the nanobioconjugates exhibited distinct intracellular trafficking and endosomal escape behavior in these cell lines, indicating their potential for addressing the challenges of cytoplasmic drug delivery and the development of therapeutics for the treatment of lysosomal storage diseases. This study presents an innovative strategy for conjugating cell-penetrating agents using silica nanoparticles and silanized fullerenol as nanostructured supports, which has the potential to enhance the efficacy of cellular drug delivery.
Integrated multi-omics analysis reveals insights into Chinese forest musk deer (Moschus berezovskii) genome evolution and musk synthesis
Authors: Feng Hui , Feng Tingyin , Mo Yidi , Sun Suli , Wang Lu , Lu Chunbin , Feng Chengli , Xing Ke , Su Zhijian
Published: May 2023

Among the artiodactyls, male animals belonging to the Family Moschidae have a unique tissue, the musk gland, with the capability of musk synthesis. However, the genetic basis of musk gland formation and musk production are still poorly understood. Here, musk gland tissues from two juvenile and three adult Chinese forest musk deer (Moschus berezovskii) were utilized to analyze genomic evolution events, evaluate mRNA profiles and investigate cell compositions. By performing genome reannotation and comparison with 11 ruminant genomes, three expanded gene families were identified in the Moschus berezovskii genome. Transcriptional analysis further indicated that the musk gland displayed a prostate-like mRNA expression pattern. Single-cell sequencing revealed that the musk gland is composed of seven distinguishable cell types. Among them, sebaceous gland cells and luminal epithelial cells play important roles in musk synthesis, while endothelial cells master the regulation of cell-to-cell communication. In conclusion, our study provides insights into musk gland formation and the musk-synthesizing process.