bluuebunny/crossref_metadata_2025 huggingface dataset:
How Evacuees Obtained Health Care Information After the Great East Japan Earthquake: A Qualitative Interview Study
Authors: Ota Haruka , Miyazaki Kikuko , Nakayama Takeo
Published: June 2017

Objective

To explore how evacuees obtained health care information at their evacuation destinations after the Great East Japan Earthquake.

Methods

We conducted semi-structured interviews of 11 evacuees who moved to City A in Kyoto Prefecture following the Great East Japan Earthquake. The interviews explored how the evacuees obtained health care information, including the main factors of influence. The interviews were transcribed and analyzed to identify trends by using the constant comparative method.

Results

Four categories emerged from 6 concepts. Mother-children evacuees and family evacuees tended to obtain health care information in different ways. Family evacuees had moved as a family unit and had obtained their health care information from local neighbors. Mother-children evacuees were mothers who had moved with their children, leaving behind other family members. These evacuees tended to obtain information from other mother-children evacuees. At the time of evacuation, we found 2 factors, emotions and systems, influencing how mother-children evacuees obtained health care information.

Conclusions

We found 2 different ways of obtaining health care information among mother-children evacuees and other evacuees. At the time of evacuation, 2 factors, emotions and systems, influenced how mother-children evacuees obtained health care information. Community-building support should be a priority from an early stage after a disaster for health care management. (Disaster Med Public Health Preparedness. 2017;11:729–734)
The Licensure of Industrial and Organizational Psychologists: It's Déjà Vu All Over Again
Authors: Kozlowski Steve W. J. , Chao Georgia T.
Published: June 2017

If one has been involved in the Society for Industrial and Organizational Psychology (SIOP) since its inception, as we have, one will have had several opportunities to reflect on the issue of licensing to regulate the practice of industrial and organizational psychology (IOP). Some find value in licensure, but the vast majority of industrial and organizational (I-O) psychologists do not. As the target article written by the Licensure of Consulting and Industrial-Organizational (I-O) Psychologists (LCIOP) Joint Task Force (2017) documents, there have been several policy statements made by SIOP leadership over the years. The essence of SIOP's policy is quite clear and consistent. Although SIOP does not support and will not promote the licensure of I-O psychologists, it does support a pathway to licensure for those who desire it, and is supportive of efforts to reduce the many barriers to licensure for those who desire it. It is our understanding that SIOP's participation in the LCIOP Joint Task Force was predicated on this long-standing policy.
The Role of Values in Professional Licensing: The Resistance to Regulation
Authors: Lefkowitz Joel
Published: June 2017

One day, a well-dressed, mature gentleman—one might be tempted to describe him as elderly, except he appears extremely vital and alert—walks into a psychotherapist's office for a first visit. After just a few brief exchanges, the therapist gets the impression that the gentleman is a socially adept, financially successful, educated professional, and a well-regarded member of the community. But all is not as it seems on the surface. This new patient “presents” with lingering complaints of vague malaise, and despite his apparent success, he reports having experienced long-term intermittent bouts of anxiety and fear stemming from threats that the therapist cannot be sure are real or imagined: Various people seem regularly aiming to put him out of business; family relatives are disrespectful, demeaning, and do not understand him. Moreover, there is an existential quality to his anxiety: As a younger, middle-aged man, although already successful, he changed his name legally because he felt it better suited his identity. In fact, he came close to changing his name twice again in recent years, but, after agonizing about it for a long time, could not make up his mind what to change it to; nothing seemed to “fit” well enough. The therapist surmised, however, that the patient was more concerned with the impression his name would make on potential business clients and competitors than with any genuine expression of his nature, and he seemed relatively unconcerned with maintaining his nominal family identification. It struck the therapist that his patient's insecurities were not in keeping with his considerable accomplishments in life. In fact, for an educated professional, the patient seemed to lack insight into his own character and values.
Mandating the Licensing of I-O Psychologists Lacks Merit
Authors: Latham Gary P.
Published: June 2017

There are at least four interrelated reasons why the practice of industrial and organizational (I-O) psychology should not require a license that is mandated by the state or province where the I-O psychologist resides. First, there is no subject matter domain unique to the practice of I-O psychology. Second, because there is no subject matter domain unique to I-O psychology, the subject matter is extensively practiced by other unregulated professions. Hence, a law mandating a license to practice I-O psychology, restricted to graduates from a doctoral program in a psychology department, is unlikely to be enforceable. It simply would not stand up to a legal challenge. Third, the espoused benefit of a mandated license, namely, to protect the public, is specious. Finally, a mandated license for the practice of I-O psychology by I-O psychologists could lead to the death of I-O psychology programs. Each of these four concerns is explained below.
Prussian Palimpsests: Historic Architecture and Urban Spaces in East Germany, 1945–1961
Authors: Colla Marcus
Published: June 2017

This article considers the fate of Prussian buildings and memorials in East Germany between 1945 and 1961. Analyzing a number of case studies from Berlin and Potsdam, it places the treatment of these structures within the broader contours of history management practices. Although this era was characterized by a strong anti-Prussian sentiment in the GDR's historical discourse, it also witnessed a complex interaction between the SED and its historical inheritance. This interaction often influenced decisions about the fate of Prussian structures in the GDR as much as any animosity toward Prussia as a historical entity did.
Measurement of KM Projects: a Practical Guide for Librarians
Authors: Russell Hélène
Published: June 2017

This article written by Hélène Russell aims to look at the measurement of Knowledge projects and activities in a simple, practical way, with the aim of helping busy law firm librarians understand whether their various Knowledge Management (KM) projects and activities are having a positive effect and are value for money in a general sense. Be forewarned: the benefits of KM are often intangible and the way that KM affects tangibles can be complex, so measurement is difficult. However, that does not mean that you cannot approximate an answer which is useful for informing business decisions.
Description of a method for inducing fetal growth restriction in the spiny mouse
Authors: Dickinson H. , Ellery S. , Davies-Tuck M. , Tolcos M. , Nitsos I. , Walker D. W. , Miller S. L.
Published: June 2017

Intrauterine or fetal growth restriction (IUGR) is a major complication of pregnancy and leads to significant perinatal morbidities and mortality. Typically, induction of IUGR in animals involves the complete occlusion or ablation of vessels to the uterus or placenta, acutely impairing blood flow and fetal growth, usually with high fetal loss. We aimed to produce a model of reduced fetal growth in the spiny mouse with minimal fetal loss. At 27 days gestational age (term is 38–39 days), a piece of silastic tubing was placed around the left uterine artery to prevent the further increase of uterine blood flow with advancing gestation to induce IUGR (occluded). Controls were generated from sham surgeries without placement of the tubing. Dams were humanely euthanized at 37 days gestational age and all fetuses and placentas were weighed and collected. Of the 17 dams that underwent surgery, 15 carried their pregnancies to 37 days gestational age and 95% of fetuses survived to this time. The difference in fetal body weight between occluded and control was ~21% for fetuses in the left uterus side: there were no differences for fetuses in the right uterus side. Offspring from the occluded group had significantly lower brain, liver, lung, kidney and carcass weights compared with shams. Preventing the gestation-related increase of uterine blood flow induced significant growth restriction in the fetal spiny mouse, with minimal fetal loss. This technique could be readily adapted for other small animal.
A Wicked View
Authors: Barrett Michael , Ervin David E. , Frisvold George B. , Jussaume Raymond A. , Shaw David R. , Ward Sarah M.
Published: June 2017

In a recent essay, Harker and coauthors stated that considering herbicide resistance as a wicked problem “without clear causes or solutions” ignores what weed scientists know about the biology and management of herbicide-resistant weeds. In this response, we argue that this misrepresents what is meant by “wicked” and that the wicked problem concept is valuable in understanding the multifaceted nature of herbicide resistance as a human-caused phenomenon.
Funktionelle Nahinfrarotspektroskopie in der sportpsychologischen Forschung
Authors: Wolff Wanja
Published: June 2017

Zusammenfassung. Ziel des Beitrags ist die Vorstellung der funktionellen Nahinfrarotspektroskopie (fNIRS) als bildgebendes Verfahren, welches zur Messung kortikaler Prozesse während sportlicher Aktivität eingesetzt werden kann. Im Vergleich mit anderen bildgebenden Verfahren ist fNIRS sehr portabel und weniger anfällig für Bewegungsartefakte. Daher ist fNIRS potentiell eine vielversprechende Ergänzung zu bereits in der sportpsychologischen Forschung genutzten neurowissenschaftlichen Methoden. Dieser Beitrag konzentriert sich auf eine kurze Darstellung der grundlegenden physikalischen Prinzipien von fNIRS und eine Analyse der relativen Stärken und Schwächen von fNIRS mit Blick auf den Einsatz in der sportpsychologischen Forschung. Anschließend werden einige fNIRS basierte Forschungsergebnisse erörtert, die sportpsychologische Forschungsfragen betreffen. Abschließend wird beispielhaft eine mögliche sportpsychologische Forschungsfrage vorgestellt, zu deren Untersuchung fNIRS eingesetzt werden kann.
MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis
Authors: Chen Qing , Yin Dan , Zhang Yong , Yu Lei , Li Xue-Dong , Zhou Zheng-Jun , Zhou Shao-Lai , Gao Dong-Mei , Hu Jie , Jin Cheng , Wang Zheng , Shi Ying-Hong , Cao Ya , Fan Jia , Dai Zhi , Zhou Jian
Published: June 2017

Ten eleven translocation (TET) enzymes convert 5-methylcytosine (5-mC) to 5-hydroxy-methylcytosine (5-hmC) and have crucial roles in biological and pathological processes by mediating DNA demethylation, however, the functional role of this epigenetic mark and the related enzymes in hepatocellular carcinoma (HCC) progression remains unknown. Here, we demonstrated that TET-family enzymes downregulation was one likely mechanism underlying 5-hmC loss in HCC. We found that miR-29a overexpression increased DNA methylation of suppressor of cytokine signaling 1 (SOCS1) promoter was associated with HCC metastasis in vitro and in vivo. Furthermore, miR-29a silenced anti-metastatic SOCS1 through direct TET-family targeting, resulting in SOCS1 promoter demethylation inhibition. Chromatin immunoprecipitation analyses confirmed that TET1 regulated SOCS1 expression through binding to the promoter region of SOCS1. Finally, miR-29a overexpression correlated with poor clinical outcomes and TET–SOCS1–matrix metalloproteinase (MMP) 9 axis silencing in HCC patients. In conclusion, our findings demonstrate that 5-hmC loss is an epigenetic hallmark of HCC, and miR-29a is an important epigenetic modifier, promoting HCC metastasis through TET–SOCS1–MMP9 axis silencing. The results offer a new strategy for epigenetic cancer therapy.
Virtual Screening, pharmacophore development and structure based similarity search to identify inhibitors against IdeR, a transcription factor of Mycobacterium tuberculosis
Authors: Rohilla Akshay , Khare Garima , Tyagi Anil K.
Published: June 2017

ideR, an essential gene ofMycobacterium tuberculosis, is an attractive drug target as its conditional knockout displayed attenuated growth phenotypein vitroandin vivo. To the best of our knowledge, no inhibitors of IdeR are identified. We carried out virtual screening of NCI database against the IdeR DNA binding domain followed by inhibition studies using EMSA. Nine compounds exhibited potent inhibition with NSC 281033 (I-20) and NSC 12453 (I-42) exhibiting IC50values of 2 µg/ml and 1 µg/ml, respectively. We then attempted to optimize the leads firstly by structure based similarity search resulting in a class of inhibitors based on I-42 containing benzene sulfonic acid, 4-hydroxy-3-[(2-hydroxy-1-naphthalenyl) azo] scaffold with 4 molecules exhibiting IC50 ≤ 10 µg/ml. Secondly, optimization included development of energy based pharmacophore and screening of ZINC database followed by docking studies, yielding a molecule with IC50of 60 µg/ml. More importantly, a five-point pharmacophore model provided insight into the features essential for IdeR inhibition. Five molecules with promising IC50values also inhibitedM. tuberculosisgrowth in broth culture with MIC90ranging from 17.5 µg/ml to 100 µg/ml and negligible cytotoxicity in various cell lines. We believe our work opens up avenues for further optimization studies.
The temporal dependence of exploration on neotic style in birds
Authors: O’Hara Mark , Mioduszewska Berenika , von Bayern Auguste , Auersperg Alice , Bugnyar Thomas , Wilkinson Anna , Huber Ludwig , Gajdon Gyula Koppany
Published: June 2017

Exploration (interacting with objects to gain information) and neophobia (avoiding novelty) are considered independent traits shaped by the socio-ecology of a given species. However, in the literature it is often assumed that neophobia inhibits exploration. Here, we investigate how different approaches to novelty (fast or slow) determine the time at which exploration is likely to occur across a number of species. We presented four corvid and five parrot species with a touchscreen discrimination task in which novel stimuli were occasionally interspersed within the familiar training stimuli. We investigated the likelihood that an animal would choose novelty at different stages of its training and found evidence for a shift in the pattern of exploration, depending on neotic style. The findings suggest that faster approaching individuals explored earlier, whilst animals with long initial approach latencies showed similar amounts of exploration but did so later in training. Age rather than species might have influenced the amount of total exploration, with juveniles exploring more than adults. Neotic style varied consistently only for one species and seems to involve a strong individual component, rather than being a purely species-specific trait. This suggests that variation in behavioural phenotypes within a species may be adaptive.
Influence of tensile-strain-induced oxygen deficiency on metal-insulator transitions in NdNiO3−δ epitaxial thin films
Authors: Heo Seungyang , Oh Chadol , Son Junwoo , Jang Hyun Myung
Published: June 2017

We report direct evidence that oxygen vacancies affect the structural and electrical parameters in tensile-strained NdNiO3−δ epitaxial thin films by elaborately adjusting the amount of oxygen deficiency (δ) with changing growth temperature TD. The modulation in tensile strain and TD tended to increase oxygen deficiency (δ) in NdNiO3−δ thin films; this process relieves tensile strain of the thin film by oxygen vacancy incorporation. The oxygen deficiency is directly correlated with unit-cell volume and the metal-insulator transition temperature (TMI), i.e., resulting in the increase of both unit-cell volume and metal-insulator transition temperature as oxygen vacancies are incorporated. Our study suggests that the intrinsic defect sensitively influences both structural and electronic properties, and provides useful knobs for tailoring correlation-induced properties in complex oxides.
Novel oestrogen receptor β-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice
Authors: Sasayama Daimei , Sugiyama Nobuhiro , Yonekubo Shigeru , Pawlak Akiko , Murasawa Hiroyasu , Nakamura Mie , Hayashi Morimichi , Ogawa Takashi , Moro Makoto , Washizuka Shinsuke , Amano Naoji , Hongo Kazuhiro , Ohnota Hideki
Published: June 2017

Hormonal changes due to menopause can cause various health problems including weight gain and depressive symptoms. Multiple lines of evidence indicate that oestrogen receptors (ERs) play a major role in postmenopausal obesity and depression. However, little is known regarding the ER subtype-specific effects on obesity and depressive symptoms. To delineate potential effects of ERβ activation in postmenopausal women, we investigated the effects of a novel oestrogen receptor β-selective ligand (C-1) in ovariectomized mice. Uterine weight, depressive behaviour, and weight gain were examined in sham-operated control mice and ovariectomized mice administered placebo, C-1, or 17β-oestradiol (E2). Administration of C-1 or E2 reduced body weight gain and depressive-like behaviour in ovariectomized mice, as assessed by the forced swim test. In addition, administration of E2 to ovariectomized mice increased uterine weight, but administration of C-1 did not result in a significant increase in uterine weight. These results suggest that the selective activation of ERβ in ovariectomized mice may have protective effects against obesity and depressive-like behaviour without causing an increase in uterine weight. The present findings raise the possibility of the application of ERβ-ligands such as C-1 as a novel treatment for obesity and depression in postmenopausal women.
A Novel Unsupervised Algorithm for Biological Process-based Analysis on Cancer
Authors: Song Tianci , Cao Sha , Tao Sheng , Liang Sen , Du Wei , Liang Yanchun
Published: June 2017

The aberrant alterations of biological functions are well known in tumorigenesis and cancer development. Hence, with advances in high-throughput sequencing technologies, capturing and quantifying the functional alterations in cancers based on expression profiles to explore cancer malignant process is highlighted as one of the important topics among cancer researches. In this article, we propose an algorithm for quantifying biological processes by using gene expression profiles over a sample population, which involves the idea of constructing principal curves to condense information of each biological process by a novel scoring scheme on an individualized manner. After applying our method on several large-scale breast cancer datasets in survival analysis, a subset of these biological processes extracted from corresponding survival model is then found to have significant associations with clinical outcomes. Further analyses of these biological processes enable the study of the interplays between biological processes and cancer phenotypes of interest, provide us valuable insights into cancer biology in biological process level and guide the precision treatment for cancer patients. And notably, prognosis predictions based on our method are consistently superior to the existing state of art methods with the same intention.
A Storage Ring Based Free-Electron Laser for Generating Ultrashort Coherent EUV and X-ray Radiation
Authors: Feng Chao , Zhao Zhentang
Published: June 2017

Generation of ultrashort coherent radiation pulses in the extreme ultraviolet (EUV) and x-ray regime is of remarkable interest in the synchrotron radiation user community. In this work, a novel technique is proposed for directly imprinting strong coherent microbunching on the electron beam with very small laser-induced energy spread. Theoretical analysis and numerical simulations demonstrated that this technique can be used for the generation of megawatt-scale level, fully temporal coherent femtosecond EUV and soft x-ray radiation pulses at a storage ring light source.
Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization
Authors: Gannavaram Sreenivas , Torcivia John , Gasparyan Lusine , Kaul Amit , Ismail Nevien , Simonyan Vahan , Nakhasi Hira L.
Published: June 2017

No licensed human vaccines are currently available against leishmaniasis. Several anti-leishmanial vaccines are currently undergoing testing, including genetically modified live-attenuated parasite vaccines. Studies with live attenuated Leishmania vaccines such as centrin deleted Leishmania donovani parasites (LdCen−/−) showed protective immunity in animal models. Such studies typically examined the biomarkers of protective immunity however the biomarkers of attenuation in the parasite preparations have not received adequate attention. As several candidate vaccines enter clinical trials, a more complete product characterization to enable maintenance of product quality will help meet regulatory requirements. Towards this goal, we have determined the complete genome sequence of LdCen−/− and its parent strain Ld1S-2D (LdWT) and characterized the LdCen−/− vaccine strain using bioinformatics tools. Results showed that the LdCen−/− parasites, in addition to loss of the centrin gene, have additional deletions ranging from 350 bp to 6900 bp in non-contiguous loci on several chromosomes, most commonly in untranslated regions. We have experimentally verified a subset of these adventitious deletions that had no impact on the attenuation of the LdCen−/− parasites. Our results identified hitherto unknown features of attenuation of virulence that could be used as markers of product quality in production lots and highlight the importance of product characterization in parasitic vaccines.
Diastereoselective synthesis of novel heterocyclic scaffolds through tandem Petasis 3-component/intramolecular Diels–Alder and ROM–RCM reactions
Authors: Ishoey Mette , Petersen Rico G. , Petersen Michael Å. , Wu Peng , Clausen Mads H. , Nielsen Thomas E.
Published: June 2017

Complexity-generating tandem Petasis 3-component/intramolecular Diels–Alder and ROM–RCM reactions for the diastereoselective synthesis of sp3-rich heterocyclic compound libraries are presented.
High-pressure crystallization and properties of diamond from magnesium-based catalysts
Authors: Palyanov Yuri N. , Kupriyanov Igor N. , Khokhryakov Alexander F. , Borzdov Yuri M.
Published: June 2017

HPHT diamond synthesis using catalysts based on magnesium demonstrates a number of intriguing characteristics. In this highlight, we review the major characteristics of the growth, morphology, internal structure, and defect and impurity content of diamonds crystallized using Mg-based catalysts.
Molecular studies of Cs adsorption sites in inorganic layered materials: the influence of solution concentration
Authors: Sato Kiminori , Hunger Michael
Published: June 2017

Radioactive Cs released into a soil environment migrates along with groundwater in a manner dependent on Cs concentration.
Photosensitization mechanism of Cu(ii) porphyrins
Authors: Uranga Jon , Matxain Jon M. , Lopez Xabier , Ugalde Jesus M. , Casanova David
Published: June 2017

This work presents the mechanism of the photoinduced generation of reactive oxygen species (ROS) by paramagnetic copper porphyrins in aqueous solution.
Mesoporous semiconducting TiO2with rich active sites as a remarkable substrate for surface-enhanced Raman scattering
Authors: Yang Libin , Yin Di , Shen Yu , Yang Ming , Li Xiuling , Han Xiaoxia , Jiang Xin , Zhao Bing
Published: June 2017

Mesoporous TiO2with highly active sites was used as an effective and recyclable substrate for SERS contributed by the charge-transfer mechanism.
Correction: Influence of particle size and dielectric environment on the dispersion behaviour and surface plasmon in nickel nanoparticles
Authors: Sharma Vikash , Chotia Chanderbhan , Tarachand Tarachand , Ganesan Vedachalaiyer , Okram Gunadhor S.
Published: June 2017

Correction for ‘Influence of particle size and dielectric environment on the dispersion behaviour and surface plasmon in nickel nanoparticles’ by Vikash Sharma et al., Phys. Chem. Chem. Phys., 2017, 19, 14096–14106.
Monitoring plasmon coupling and SERS enhancement through in situ nanoparticle spacing modulation
Authors: Velleman L. , Scarabelli L. , Sikdar D. , Kornyshev A. A. , Liz-Marzán L. M. , Edel J. B.
Published: June 2017

Self-assembled nanoparticle (NP) arrays at liquid interfaces provide a unique optical response which has opened the door to new tuneable metamaterials for sensing and optical applications. NPs can spontaneously assemble at a liquid–liquid interface, forming an ordered, self-healing, low-defect 2D film. The close proximity of the NPs at the interface results in collective plasmonic modes with a spectral response dependent on the distance between the NPs and induces large field enhancements within the gaps. In this study, we assembled spherical and rod-shaped gold NPs with the aim of improving our understanding of NP assembly processes at liquid interfaces, working towards finely controlling their structure and producing tailored optical and enhanced Raman signals. We systematically tuned the assembly and spacing between NPs through increasing or decreasing the degree of electrostatic screening with the addition of electrolyte or pH adjustment. The in situ modulation of the nanoparticle position on the same sample allowed us to monitor plasmon coupling and the resulting SERS enhancement processes in real time, with sub-nm precision.
Tandem dehydration–transfer hydrogenation reactions of xylose to furfuryl alcohol over zeolite catalysts
Authors: Paulino Priscilla N. , Perez Rafael F. , Figueiredo Natália G. , Fraga Marco A.
Published: June 2017

Dehydration and transfer hydrogenation tandem reactions of xylose to furfuryl alcohol in water/isopropanol were performed on MFI, FAU and BEA zeolites.
Catalytic Radical Intramolecular Aminoperfluoroalkylation and Aminodifluoromethylation of Unactivated Alkenes with Fluoro­alkylsulfonyl Chlorides
Authors: Liu Xin-Yuan , Li Xue-Fei , Lin Jin-Shun
Published: June 2017

The Cu(I)/phosphoric acid (PA) dual-catalyzed radical aminoperfluoroalkylation and aminodifluoromethylation of alkenes with commercially available fluoroalkylsulfonyl chlorides as the radical source is described. Functionalized α-tertiary pyrrolidines bearing four types of fluoroalkyl groups are obtained with moderate to excellent yields. The introduction of a Cu(I)/phosphoric acid dual catalytic system and the use of silver carbonate as a key additive to inhibit the side hydroamination reaction caused by the in situ generated HCl are crucial for the transformation.
A modification of the projective construction of quantum states for field theories
Authors: Kijowski Jerzy , Okołów Andrzej
Published: June 2017

The projective construction of quantum states for field theories may be flawed—in some cases, the construction may possibly lead to spaces of quantum states which are “too small” to be used in quantization of field theories. Here we present a slight modification of the construction which is free from this flaw.
Unexpected significant increase in bulk conductivity of a dielectric arising from charge injection
Authors: Wang Jian-Jun , Bayer Thorsten J. M. , Wang Rui , Carter Jared J. , Randall Clive A. , Chen Long-Qing
Published: June 2017

Charge injection is a common phenomenon in heterostructures or devices containing metal-insulator interfaces under a voltage bias ranging from dielectric capacitors to electroluminescent and lasing devices. It is generally believed that charge injection only significantly increases the conductivity near the interfacial region or in capacitors with very thin dielectric layers. In this work, the impact of charge injection on bulk conductivity of a 0.5 mm thick Fe-doped SrTiO3 single crystal is investigated with a combination of experimental impedance measurements and computational modelling. It is found that the interfacial charge injection may increase the predicted bulk conductivity of a dielectric by more than one order of magnitude as a consequence of Schottky barrier height lowering.
Role of threading dislocations in strain relaxation during GaInN growth monitored by real-time X-ray reflectivity
Authors: Ju Guangxu , Tabuchi Masao , Takeda Yoshikazu , Amano Hiroshi
Published: June 2017

Ga1−xInxN epilayers (x = 0.09 or 0.14) grown on c-plane GaN layers with different densities of threading dislocations have been investigated by real-time x-ray reflectivity during metal-organic vapor phase epitaxial growth. We found that the density of pre-existing threading dislocations in GaN plays an important role in the strain relaxation of Ga1−xInxN. Critical thicknesses were obtained and compared with theoretical predictions using the mechanical equilibrium model and the energy balance model. The critical thickness of GaInN varies inversely with dislocation density in the GaN sublayer. When the threading dislocation density in the sublayer was reduced by three orders of magnitude, the photoluminescence intensity of the Ga0.86In0.14N epilayer was improved by a factor of ten.
Electrical domain writing and nanoscale potential modulation on LaVO3/SrTiO3
Authors: Balal Mohammad , Sanwlani Shilpa , Wadehra Neha , Chakraverty Suvankar , Sheet Goutam
Published: June 2017

The high-mobility 2 dimensional electron gases formed at the interfaces between certain insulating perovskite oxides have known to be a playground of exotic physical orders like superconductivity and ferromagnetism and their inter-coupling. There have been efforts to accomplish electronic confinement at such interfaces of oxide heterostructures through nano-structuring of the surface. In this paper, we report writing and erasing charge domains on such an oxide heterostructure LaVO3/SrTiO3 using a conductive AFM cantilever. We have patterned these domains in a periodic fashion in order to create artificial lattices on the surface. Through kelvin probe microscopy, electrostatic force microscopy, and conductivity mapping of such artificial lattices, we found that the domains not only trap charge carriers but also develop a controllable potential landscape on the surface which coincides with a modulation of local electrical conductivity. The ability to pattern such nanostructures reversibly offers unprecedented opportunities of realizing ultra-high storage density devices in high mobility oxide heterostructures.
Metodología de elaboración de un glosario bilingüe y bidireccional (inglés-español/español-inglés) basado en corpus para la traducción de manuales de instrucciones de televisores
Authors: Seghiri Miriam
Published: June 2017

The sources of information that translators may use are extremely varied, ranging from oral consultation with an expert to a search using specialised dictionaries and glossaries. Nowadays, however, one the most relevant documentation activities in the field of Translation involves the use of Internet resources and, closely related to this, the compilation and management of virtual corpora. For this reason, in the present paper we present a systematic methodology for extracting bilingual and bidirectional glossaries (English-Spanish/Spanish-English) based on parallel corpora to translate TV User Manuals. In fact, according to art. 5 of the Council Resolution of 17 December 1998 on operating instructions for technical consumer goods (98/C 411/01) it is essential to control the quality when writing and translating these manuals. In order to illustrate this methodology we focus on corpus design (according to the skopo) and on the compilation protocol (in four steps: searching, downloading, text formatting and saving data) in order to ensure quality. As for the quantity, we check the quantitative representativeness with the ReCor software (cfr. Seghiri 2006: 387). Once the corpus is representative from the qualitative and the quantitative points of view, it can be managed with a concordance program. So, we illustrate how to extract the terms semiautomatically in order to build a bilingual and bidirectional glossary with a parallel concordance named ParaConc. Thus, in the present paper we combine the main resource for researchers (cfr. Bowker 1998; Varantola 2000; Seghiri 2011) within the Translation field: corpora, in order to ensure quality; and the main documentation resource for prospective translators (cfr. Corpas et al. 2001): bilingual glossaries.
Searching for “Agent Zero”
Authors: van den Bos Jackie , Meakins Felicity , Algy Cassandra
Published: June 2017

Gurindji Kriol, a mixed language spoken in northern Australia, combines a Kriol VP with a Gurindji NP, including case suffixes (Meakins 2011a). The Gurindji-derived case suffixes have undergone a number of changes in Gurindji Kriol, for example the ergative suffix -ngku/-tunow marks nominative case (Meakins 2011b,2015). This study explores a new innovation in case morphology among Gurindji Kriol-speaking children: the use of -ngku/-tuto mark possessors as well as subjects, i.e. the emergence of a relative case system. Although rare in Australian languages, syncretism between agents and possessors is not uncommon cross-linguistically, reported in Caucasian Eskimo-Aleut, Mixe-Zoquean and Yucatecan-Mayan languages (Allen 1964;Blake 1994;Palancar 2002). In the case of Gurindji Kriol, the relative case system found its origins in allomorphic reduction which led to syncretism between ergative and dative case forms. This syncretism was shaped by the syntactic grouping of subjects and possessors as dependents of verbs and possessums, respectively. Although partial syncretism between ergative and dative case is not unusual in Australian languages historically, it has gone to completion in Gurindji Kriol and can be observed in two other instances of rapid linguistic change in Australia: Ngiyambaa (Donaldson 1980) and Dyirbal (Schmidt 1985). The re-organisation of the case system can be traced back to a small group of second-generation Gurindji Kriol speakers at Nitjpurru (Pigeon Hole) and this change has since been transmitted laterally through familial connections to other children at Daguragu. There are also indications that it has begun propagating to other children at Kalkaringi and is now being acquired by the next generation of Gurindji Kriol speakers.
A language learner’s target language-mediated socializing in an affinity space in the host country
Authors: Fukada Yoshifumi
Published: June 2017

The number of international students keeps increasing worldwide. This is partly attributed to their expectation of improving their language skills by actually using the target language (TL) in the host countries. However, past studies show that such opportunities are not automatically given to them. Perceiving himself as one English learner, the author conducted an autoethnography to explore the processes of availing of opportunities to use the TL in Hawaii during his sabbatical. By recording observations and informal interviews in a diary of his own TL-mediated socialization, the author found that he could engage himself as an active social agent within a type of social space called affinity space which greatly promoted his situated TL-learning in naturalistic contexts. The author discusses how his own case can be applied to other learners studying abroad and presents some educational implications.
Feeding of the water extract from Ganoderma lingzhi to rats modulates secondary bile acids, intestinal microflora, mucins, and propionate important to colon cancer
Authors: Yang Yongshou , Nirmagustina Dwi Eva , Kumrungsee Thanutchaporn , Okazaki Yukako , Tomotake Hiroyuki , Kato Norihisa
Published: June 2017

Consumption of reishi mushroom has been reported to prevent colon carcinogenesis in rodents, although the underlying mechanisms remain unclear. To investigate this effect, rats were fed a high-fat diet supplemented with 5% water extract from either the reishi mushroom (Ganoderma lingzhi) (WGL) or the auto-digested reishi G. lingzhi (AWGL) for three weeks. Both extracts markedly reduced fecal secondary bile acids, such as lithocholic acid and deoxycholic acid (colon carcinogens). These extracts reduced the numbers of Clostridium coccoides and Clostridium leptum (secondary bile acids-producing bacteria) in a per g of cecal digesta. Fecal mucins and cecal propionate were significantly elevated by both extracts, and fecal IgA was significantly elevated by WGL, but not by AWGL. These results suggest that the reishi extracts have an impact on colon luminal health by modulating secondary bile acids, microflora, mucins, and propionate that related to colon cancer.
MicroRNA-210 alleviates oxidative stress-associated cardiomyocyte apoptosis by regulating BNIP3
Authors: Diao Hongying , Liu Bin , Shi Yongfeng , Song Chunli , Guo Ziyuan , Liu Ning , Song Xianjing , Lu Yang , Lin Xiaoye , Li Zhuoran
Published: June 2017

Oxidative stress-induced myocardial apoptosis and necrosis are involved in ischemia/reperfusion (I/R) injury. This study was performed to investigate microRNA (miR)-210’s role in oxidative stress-related myocardial damage. The expression of miR-210 was upregulated in myocardial tissues of I/R rats, while that of Bcl-2 adenovirus E1B 19kDa-interacting protein 3 (BNIP3) was downregulated. To simulate in vivo oxidative stress, H9c2 cells were treated with H2O2 for 48 h. MiR-210 level was increased upon H2O2 stimulation, peaked at 8 h, and then decreased. An opposite expression pattern of BNIP3 was observed. BNIP3 was demonstrated as a direct target of miR-210 via luciferase reporter assay. H2O2-induced cell apoptosis was attenuated by miR-210 mimics, whereas aggravated by miR-210 inhibitor. MiR-210 knockdown-induced cell apoptosis in presence of H2O2 was attenuated by BNIP3 siRNA. Our work demonstrates that miR-210 plays a protective role in H2O2-induced cardiomyocyte apoptosis at least by regulating the pro-apoptotic BNIP3.
The Cluster-EAGLE project: global properties of simulated clusters with resolved galaxies
Authors: Barnes David J. , Kay Scott T. , Bahé Yannick M. , Dalla Vecchia Claudio , McCarthy Ian G. , Schaye Joop , Bower Richard G. , Jenkins Adrian , Thomas Peter A. , Schaller Matthieu , Crain Robert A. , Theuns Tom , White Simon D. M.
Published: June 2017

We introduce the Cluster-EAGLE (c-eagle) simulation project, a set of cosmological hydrodynamical zoom simulations of the formation of 30 galaxy clusters in the mass range of 1014 < M200/M⊙ < 1015.4 that incorporates the Hydrangea sample of Bahé et al. (2017). The simulations adopt the state-of-the-art eagle galaxy formation model, with a gas particle mass of 1.8 × 106 M⊙ and physical softening length of 0.7 kpc. In this paper, we introduce the sample and present the low-redshift global properties of the clusters. We calculate the X-ray properties in a manner consistent with observational techniques, demonstrating the bias and scatter introduced by using estimated masses. We find the total stellar content and black hole masses of the clusters to be in good agreement with the observed relations. However, the clusters are too gas rich, suggesting that the active galactic nucleus (AGN) feedback model is not efficient enough at expelling gas from the high-redshift progenitors of the clusters. The X-ray properties, such as the spectroscopic temperature and the soft-band luminosity, and the Sunyaev–Zel'dovich properties are in reasonable agreement with the observed relations. However, the clusters have too high central temperatures and larger-than-observed entropy cores, which is likely driven by the AGN feedback after the cluster core has formed. The total metal content and its distribution throughout the intracluster medium are a good match to the observations.
Donor-Site Complications and Remnant of Rectus Abdominis Muscle Status after Transverse Rectus Abdominis Myocutaneous Flap Reconstruction
Authors: Chirappapha Prakasit , Trikunagonvong Noppadol , Prapruttam Duangkamon , Rongthong Sasiprapa , Lertsithichai Panuwat , Sukarayothin Thongchai , Leesombatpaiboon Monchai , Panawattanakul Rujira , Thaweepworadej Panya
Published: June 2017

Background:

Transverse rectus abdominis myocutaneous (TRAM) flap reconstruction after mastectomy in breast cancer patients has become one of the milestones in breast reconstruction. There are several techniques that have been used in an attempt to minimize untoward complications. We present the whole muscle with partial sheath-sparing technique that focuses on the anatomy of arcuate line and the closure of the anterior abdominal wall techniques with mesh and determine factors associated with its complications and outcomes.

Methods:

We retrospectively and prospectively review the results of 30 pedicled TRAM flaps that were performed between November 2013 and March 2016, focusing on outcomes and complications.

Results:

Among the 30 pedicled TRAM flap procedures in 30 patients, there were complications in 5 patients (17%). Most common complications were surgical-site infection (7%). After a median follow-up time of 15 months, no patient developed abdominal wall hernia or bulging in daily activities in our study, but 6 patients (20%) had asymptomatic abdominal wall bulging when exercised. Significant factors related to asymptomatic exercised abdominal wall bulging included having a body mass index of more than 23 kg/m2.

Conclusion:

Pedicled TRAM flap by using the technique of the whole muscle with partial sheath-sparing technique combined with reinforcement above the arcuate line with mesh can reduce the occurrence of abdominal bulging and hernia.
Pneumococcal Meningitis Before and After Universal Vaccination With Pneumococcal Conjugate Vaccines 7/13, Impact on Pediatric Hospitalization in Public and Nonpublic Institutions, in Uruguay
Authors: Pírez María Catalina , Mota María Inés , Giachetto Gustavo , Sánchez Varela Mercedes , Galazka Jeannette , Gutierrez Stella , Varela Adriana , Picón Teresa , Algorta Gabriela
Published: June 2017

This is the first study showing the impact of 13-valent pneumococcal conjugate vaccine on pneumococcal meningitis in Latin America; a significant (63.5%) reduction in hospitalization was observed during the first 6 years after starting vaccination. A 90% reduction of pneumococcal conjugate vaccines 7/13 serotypes was observed (P < 0.0001). After vaccination, all strains were penicillin susceptible. Mortality had a reduction of 71%.
Pyogenic Tenosynovitis in Infants
Authors: Lironi Céline , Steiger Christina , Juchler Céline , Spyropoulou Vasiliki , Samara Eleftheria , Ceroni Dimitri
Published: June 2017

Pyogenic tenosynovitis is an uncommon condition in children, and there are few published case reports. We present a series of 11 cases who were treated in the Geneva Children Hospital in the last 10 years. Kingella kingae was the main pathogen, and the characteristics of infection (inflammatory indices, clinical findings and severity) are similar to other osteoarticular K. kingae infections in infants.
Internet Stroke Preparedness for African American Women
Authors: Beal Claudia C.
Published: June 2017

Background: African American women exhibit low stroke awareness and may benefit from experiential and lay language description of stroke symptoms. Objectives: The purpose of this pilot study was to examine the effect of an online stroke preparedness intervention for identification of stroke symptoms and appropriate action in response to suspected stroke and estimate effect sizes for a larger study. Methods: A quasi-experimental nonequivalent comparison group design was used to randomized 44 women to intervention (n = 23) or wait-list control group (n = 21). Data were analyzed with Friedman and Wilcoxon signed rank tests and Cochran-Mantel-Haenszel statistics to examine intervention effect on (1) self-efficacy to recognize stroke and know what to do in the event of stroke, (2) awareness of stroke symptoms, and (3) behavioral intent to call 911 for suspected stroke. Effect size estimates were calculated by converting z scores to r. Results: Significant intervention effect was found for self-efficacy to know what to do in the event of stroke, ability to identify stroke symptoms presented in written vignettes, and ability to identify correct action in response to symptoms presented in written vignettes. Small to medium effect sizes were obtained. No improvement was found for ability to name stroke symptoms. Behavioral intent to call 911 for stroke in someone else was high, but significantly fewer women would call 911 for themselves. Conclusions: Experiential depictions of stroke symptoms in an online format showed preliminary effectiveness to improve stroke awareness among African American women.
Cessation of Continuous Flow Left Ventricular Assist Device–Related Gastrointestinal Bleeding After Heart Transplantation
Authors: Patel Snehal R. , Oh Kyung Taek , Ogriki Tolulope , Sims Daniel , Shin J. Julia , Madan Shivank , Saeed Omar , Goldstein Daniel J. , Jorde Ulrich P.
Published: June 2017

Gastrointestinal bleeding (GIB) is a major complication of continuous flow left ventricular assist device (CF LVAD) therapy. The precise pathophysiology of CF LVAD–related bleeding remains poorly understood, and the effect of pump removal at the time of transplantation on actual bleeding frequency has not previously been studied. A single-center retrospective review was conducted on patients who received CF LVAD and subsequently developed GIB. Baseline demographics and markers of pulsatility (aortic valve opening and the HeartMate II [HM2] pulse index) were compared between those with and without GIB. In those patients who had GIB and proceeded to heart transplantation, the frequency and etiology of recurrent GIB post-transplant was assessed. A total of 88 GIBs occurred in 54 of 214 patients who received CF LVAD implantation (25%, 0.36 events per patient-year). Median time to first bleeding was 65 (interquartile range [IQR]: 37–229) days, and arteriovenous malformation (AVM) was the etiology in 36% of all episodes. On multivariate analysis, age (odds ratio [OR]: 1.05; 95% confidence interval [CI]: 1.01–1.09; p = 0.006) and HM2 pulse index (OR: 0.57; 95% CI: 0.35–0.90; p = 0.017) were significantly associated with GIB. There were 28 patients who had at least one GIB event during LVAD support and proceeded to transplant. None of these patients had recurrent bleeding after heart transplantation. This is the first documentation that transplantation effectively eliminates CF LVAD–related GIB. Current guidelines recommending prioritization for transplant for patients who develop recurrent GIB after CF LVAD are justified.