bluuebunny/crossref_metadata_2025 huggingface dataset:
Drug alcohol interactions-a review
Authors: Vantaku Shyam Kumar , Boddepalli Rakesh , Ramakrishna  , B Keerthana , B Vidyasagar , Pasala Asha
Published: December 2022

Chronic Alcoholics can induce interactions with various drugs. Mainly the pharmacokinetic and pharmacodynamics interactions between drugs and alcohol plays an important role. Alcohol can cause potentiallyl harmful effects When people are unaware of known drug interactions, Knowingly combine due to negligence, As a tool to facilitate a crime. Most of the drugs involved are benzodiazepines, cocaine, NSAIDS, metronidazole caution, awareness, and education about the consequences should be enhanced within the alcoholic abusers who are in medication which can cause potential interactions and secondary effects. The elderly and chronic drug abusers are at risk mostly.
Case study on phenylketonuria: a memic autism
Authors: K Nikhila , V Sahithi , V Yaswanth Reddy , G Venkata Nagaraju , Sitty Manohar Babu
Published: December 2022

Phenylketonuria (PKU) is a phenylalanine catabolism metabolic condition characterized by a decrease in the activity of the phenylalanine hydroxylase or Dihydro pteridine reductase enzyme. This inherited condition causes a build-up of phenylalanine in the bloodstream. Elevated phenylalanine levels in the blood can cause muscle rigidity, choreoathetosis, tremors, hyperreflexia, dermatitis, pale skin, and pseudo-scleroderma. The central nervous system deficiencies in PKU are caused by phenylalanine and phenyl pyruvic acid competing for dopamine, adrenaline, norepinephrine, and serotonin in the brain. Structural changes are caused by neurotransmitter inhibition and phenylalanine and phenyl pyruvic accumulations in the white matter of the posterior periventricular, frontal, and subcortical areas of the brain1. Greater myelin turnover decreased synaptogenesis, and reduced neuronal digenesis ensues from myelin deficit, resulting in cognitive development and mental retardation1. The patient in this case study is an 8-year-old boy who has been diagnosed with phenylketonuria. The patient’s parents had a history of consanguinity marriage. The patient has had seizures since he was nine months old. Speech and language delays, hearing loss, and tooth discoloration are all common symptoms. He had an MRI and a brain scan, as well as a blood amino acids test, which revealed that he has mild developmental delays. Mild to Moderate Autistic Features is Delayed.
History of the Second Industrial Revolution. Scientific Research of Faculty of Economics
Authors: Khudokormov A. G.
Published: December 2022

Article is designed to expand the course on the history of the national economy through the introduction of global topics (in addition to sections on the development of individual countries and regions). The article deals with the spasmodic development of world industry in the second half of the 19th - early 20th centuries. Data are given on the rapid development of the electric power industry and electrical engineering, metallurgy, various means of transport (cars, aircraft, etc.), as well as types of weapons. In conclusion, a general analysis of the social changes caused by the Second In-dustrial Revolution in the most developed, technically advanced countries of the world is presented.
Increasing Efficiency and Implementing the Principles of Leanness in the Production of Sandwich Panels for Special Vehicles
Authors: Devyatov I. V. , Tuev D. V.
Published: December 2022

In the article, based on the experience of implementing the principles of lean manufacturing and the Kaizen ideology at industrial enterprises, as well as on the basis of the work of a number of specialists in the organization of production, steps are proposed to improve the efficiency of the pro-duction of sandwich panels for special vehicles, proposals are formulated for the introduction of a number of lean manufacturing tools and formed an idea of the potential effect of the implementation of the proposed measures at the stage of production start-up.
Las categorías Base y Fundamento en el proceso y resultado de la investigación científica educacional peruana
Authors:   Universidad Marcelino Champagnat, Aguirre Chávez Felipe
Published: December 2022

El presente estudio tuvo como objetivo analizar las categorías base y fundamento en el proceso y resultado la investigación científica educacional peruana en docentes de educación básica. Metodológicamente el estudio corresponde a investigaciones teóricas de revisión de la literatura sobre el desempeño docente. Y desde la utilización de métodos teóricos de análisis y síntesis, se ha llegado a concluir que en la práctica educativa hay prevalencia de dos vicios epistemológicos, empirismo y dispersión teórica.
Validación de un instrumento para medir la percepción de los docentes universitarios sobre las clases virtuales
Authors:   Universidad Nacional del Centro del Perú, López Rengifo Carlos Fernando , Esteban Rivera Edwin Roger ,   Universidad Nacional Hermilio Valdizán, Piñas Rivera Livia Cristina ,   Universidad Nacional de Educación, Rojas Cotrina Amancio Ricardo ,   Universidad Nacional Hermilio Valdizán
Published: December 2022

En la investigación se describe el proceso de construcción y validación de un instrumento que permita recoger información sobre el desempeño del docente universitario. La investigación documentaria, la entrevista a expertos y el criterio de los investigadores, que indican un enfoque cualitativo en la fase 1 de construcción, nos dieron la primera versión de la propuesta de dicho instrumento, en la que se tomaron como base los aportes del modelo TAM, y las opiniones de los expertos en educación virtual, con la característica de inclusión que sean docentes universitarios. Luego, se aplicó el enfoque cuantitativo en la fase 2 de validación, utilizando la técnica de jueces, en la que luego del pedido de colaboración de los jueces (docentes universitarios con experiencia en manejo de TIC), 10 colaboraron con su apreciación en las dimensiones Claridad, Coherencia, Relevancia por ítem y suficiencia por dimensión. Dichos resultados se procesaron con la V de Aiken y en función a su baremo de interpretación se hicieron las mejoras correspondientes, obteniendo así el instrumento validado que se muestra en el apéndice del artículo.
Experiências decoloniais: por uma pós-graduação antirracista
Authors:   Universidade Federal de Mato Grosso, de Castilho Suely Dulce
Published: December 2022

Este artigo tem objetivo refletir sobre programas de extensão universitária com vistas à formação de docentes quilombolas, como um modo de responder aos movimentos dos/as docentes das comunidades tradicionais negras rurais, por uma formação que atenda seus anseios identitários e culturais; e por outro lado, refletir sobre a importância do comprometimento da instituição universitária, e da pesquisa, como agentes de transformação social. Metodológicamente parte de experiencias de pesquisa-extensão-ação, desenvolvida no âmbito do Grupo de estudos e Pesquisas em Educação Quilombola, da Universidade Federal de Mato Grosso/GEPEQ/PPGE/UFMT/BRASIL; e do Laboratório de Pesquisa e Extensão com populações Tradicionais, Afroamericanas/LaPPA/IFHC/UNICAMP/BRASIL. Teoricamente dialoga com estudos das abordagens pós-colonial, decolonial, somados aos pressupostos dos etnosaberes e teoria crítica da educação e do currículo. A finalidade é pensar a pesquisa como ações coletivas entre os/as atores/as envolvidos/as na busca por justiça racial com desdobramentos educacionais. Os resultados apontam um crescente engajamento dos Programas de Pós-Graduação das universidades públicas brasileiras na adoção de políticas afirmativas para ingresso da população minorizada, incluido a negra, rural e quilombola nos seus Programas de Pós-Graduação, no entanto, ainda é necessário ampliar o alcance, assim como avançar no aprimoramento para um currículo de formação pluriversal.
Study on Slag-Rice Husk Ash based Alkali Activated Concrete
Authors: Das D. , Laskar S.M. , Hussain B.
Published: December 2022

Alkali activated binder is an innovative material and a potential alternate to conventional Portland cement for use in construction applications. Alkali activated binder is prepared using industrial or agro based by-products such as ground granulated blast furnace slag, fly-ash, rice husk ash, etc. This paper presents the processes and tests involved in evaluation of the strength and workability of slag-rice husk ash based alkali activated concrete. Raw rich hush ash was collected from various sources, ground and tested to attain suitable fineness and use in preparation of the concrete. Blast furnace slag and rice husk ash were incorporated in various percentages to prepare the alkali activated concrete. Results from the tests were compared with that of conventional Portland concrete. The fineness of rice husk as well as the amount played significant role in altering the properties of alkali activated concrete. Porousness of rice husk ash lowers the workability and compressive strength.
Analysis of Smart Functionally Graded Beams combined with piezoelectric material using Finite Element Method
Authors: Pradhan N. , Sarangi S.K. , Basa B.
Published: December 2022

The present work devotes the static and vibration behaviour of Smart Functionally Graded (SFG) Beams combined with piezoelectric material. In this work, Lead Zirconate Titanate (PZT-4) is taken as the piezoelectric material which is commercially available. The efficiency of piezoelectric material integrated onto the functionally graded (FG) beams is evaluated. A finite element model is made for the FG beam combined with piezoelectric material considering first order theory (FSDT). The material properties of the FG beam is graded along the direction of its thickness following power law distribution method. Simulation models are also made employing finite element software (ANSYS) for the functionally graded beams. Different boundary conditions as well as and power law indexes are taken for analysis. Validation of results is presented with the results available in earlier research publications. Effects of gradation of material properties on static and dynamic behaviour of smart functionally graded beam are studied. Efforts are also made to examine the performance of piezoelectric patches towards control of deflections and vibrations.
M33 Cepheids from CFHT/MegaCam Survey
Authors: Adair Samuel , Lee 李 Chien-Hsiu 見修
Published: December 2022

In this paper we analyze Sloan g,
r,
i archival imaging data of M33 taken by Hartman et al. using MegaCam at the Canada–France–Hawaii Telescope. To determine the distance to the M33 galaxy, we performed several analytical steps to identify its Cepheid population. We used the Lomb–Scargle algorithm to find periodicity and visually identified 1989 periodic variable stars. Since Cepheids occupy a specific region of the color–magnitude diagram, to differentiate Cepheids from other variables we used the expected position of the Cepheid instability strip to down-select Cepheids in M33 from other variables. This led to our sample of 1622 variables, the largest Cepheid sample known in M33 to date. We further classified these Cepheids into different subclasses, and used the fundamental mode Cepheids to estimate distance moduli for M33 in different filters: μ = 25.044 ± 0.083 mag in the g filter, μ = 24.886 ± 0.074 mag in the r filter, and μ = 24.785 ± 0.068 mag for the i filter. These results are in agreement with previous results.
An Interpretable Machine-learning Framework for Modeling High-resolution Spectroscopic Data*
Authors: Gully-Santiago Michael , Morley Caroline V.
Published: December 2022

Comparison of échelle spectra to synthetic models has become a computational statistics challenge, with over 10,000 individual spectral lines affecting a typical cool star échelle spectrum. Telluric artifacts, imperfect line lists, inexact continuum placement, and inflexible models frustrate the scientific promise of these information-rich data sets. Here we debut an interpretable machine-learning framework blasé that addresses these and other challenges. The semiempirical approach can be viewed as “transfer learning”—first pretraining models on noise-free precomputed synthetic spectral models, then learning the corrections to line depths and widths from whole-spectrum fitting to an observed spectrum. The auto-differentiable model employs back-propagation, the fundamental algorithm empowering modern deep learning and neural networks. Here, however, the 40,000+ parameters symbolize physically interpretable line profile properties such as amplitude, width, location, and shape, plus radial velocity and rotational broadening. This hybrid data-/model-driven framework allows joint modeling of stellar and telluric lines simultaneously, a potentially transformative step forward for mitigating the deleterious telluric contamination in the near-infrared. The blasé approach acts as both a deconvolution tool and semiempirical model. The general-purpose scaffolding may be extensible to many scientific applications, including precision radial velocities, Doppler imaging, chemical abundances for Galactic archeology, line veiling, magnetic fields, and remote sensing. Its sparse-matrix architecture and GPU acceleration make blasé fast. The open-source PyTorch-based code blase includes tutorials, Application Programming Interface documentation, and more. We show how the tool fits into the existing Python spectroscopy ecosystem, demonstrate a range of astrophysical applications, and discuss limitations and future extensions.
A Population III–Generated Dust Screen at z ∼ 16
Authors: Melia Fulvio
Published: December 2022

The search for alternative cosmological models is largely motivated by the growing discordance between the predictions of ΛCDM and the ever-improving observations, such as the disparity in the value of H
0 measured at low and high redshifts. One model in particular, known as the R
h = ct universe, has been highly successful in mitigating or removing all of the inconsistencies. In this picture, however, the anisotropies in the cosmic microwave background (CMB) would have emerged at a redshift z ∼ 16, rather than via fluctuations in the recombination zone at z ∼ 1080. We demonstrate here that a CMB created in the early universe, followed by scattering through a Population III–generated dust screen, is consistent with all of the current data. Indeed, the Planck measurements provide a hint of an ∼2%–4% frequency dependence in the CMB power spectrum, which would be naturally explained as a variation in the optical depth through the dust but not a Thomson scattering–dominated recombination environment. Upcoming measurements should be able to easily distinguish between these two scenarios, e.g., via the detection of recombination lines at z ∼ 1080, which would completely eliminate the dust-reprocessing idea.
New Constraints on the Dark Matter Density Profiles of Dwarf Galaxies from Proper Motions of Globular Cluster Streams
Authors: Malhan Khyati , Valluri Monica , Freese Katherine , Ibata Rodrigo A.
Published: December 2022

The central density profiles in dwarf galaxy halos depend strongly on the nature of dark matter (DM). Recently, in Malhan et al. we employed N-body simulations to show that the cuspy cold DM subhalos predicted by cosmological simulations can be differentiated from cored subhalos using the properties of accreted globular cluster (GC) streams since these GCs experience tidal stripping within their parent halos prior to accretion onto the Milky Way. We previously found that clusters that are accreted within cuspy subhalos produce streams with larger physical widths and higher dispersions in line-of-sight velocity and angular momentum than streams that are accreted within cored subhalos. Here, we use the same suite of simulations to demonstrate that the dispersion in the tangential velocities of streams (

σ

v

Tan

) is also sensitive to the central DM density profiles of their parent dwarfs and GCs that they were accreted from; cuspy subhalos produce streams with larger

σ

v

Tan

than those accreted inside cored subhalos. Using Gaia EDR3 observations of multiple GC streams we compare their

σ

v

Tan

values with simulations. The measured

σ

v

Tan

values are consistent with both an “in situ” origin and with accretion inside cored subhalos of M ∼ 108–9
M
⊙ (or very low-mass cuspy subhalos of mass ∼108
M
⊙). Despite the large current uncertainties in

σ

v

Tan

, we find a low probability that any of the progenitor GCs were accreted from cuspy subhalos of M ≳ 10 9
M
⊙. The uncertainties on Gaia tangential velocity measurements are expected to decrease in future and will allow for stronger constraints on subhalo DM density profiles.
Exploring the eDNA dynamics of the host-pathogen pair Pacifastacus leniusculus (Decapoda) and Aphanomyces astaci (Saprolegniales) under experimental conditions
Authors: Rusch Johannes C. , Strand David A. , Laurendz Charlotte , Andersen Tom , Johnsen Stein I. , Edsman Lennart , Vrålstad Trude
Published: December 2022

The oomycete Aphanomyces astaci causes crayfish plague, a disease threatening native European crayfish. It is carried and transmitted by American crayfish species, which are the original hosts of A. astaci. In recent years, environmental DNA (eDNA) methods have been successfully implemented to monitor the spread of both A. astaci and its hosts. However, still little is known about how population density and other environmental factors influence the detectability of this host-pathogen complex. In a mesocosm experiment, we tested the influence of crayfish density, temperature and food availability on the detectability of eDNA for A. astaci and its host, signal crayfish Pacifastacus leniusculus. We also compared eDNA results with crayfish population density measured by catch per unit effort (CPUE) from two lakes with varying crayfish density and A. astaci prevalence. The mesocosm experiment revealed that a limited set of controlled factors can substantially change the detectable amount of eDNA, even though the physical presence of the target organisms remains the same. In cold, clear water, eDNA quantities of both targets increased far more than in a linear fashion with increased crayfish density. However, the presence of food decreased the detectability of crayfish eDNA, presumably through increased microbial-induced eDNA degradation. For A. astaci, where eDNA typically represents living spores, food did not affect the detectability. However, high water temperature strongly reduced it. The increased complexity and variability of factors influencing eDNA concentration under natural conditions, compared to a controlled experimental environment, suggests that establishing a reliable relationship between eDNA quantities and crayfish density is difficult to achieve. This was also supported by field data, where we found minimal correspondence between eDNA quantity and CPUE data. A comparison between quantitative real-time PCR (qPCR) analysis and droplet-digital PCR (ddPCR) analysis revealed higher detection success of the targets in field samples when using qPCR. Overall, our results support eDNA as an effective tool for presence-absence monitoring, but it seems less suited for biomass quantification and population density estimates. Detection of A. astaci and P. leniusculus is not influenced uniformly by respective environmental factors. Consequently, we recommend a strategy of monitoring both targets, where the detection of one may point towards the presence of the other.
L’ethnographie en procès
Authors: Laurens Sylvain
Published: December 2022

Ce texte propose une introduction et une mise en discussion des articles publiés par Shamus Khan et Jack Katz autour de la convocation judiciaire dont a pu faire l’objet le premier des deux sociologues. Cette affaire est notamment l’occasion d’actualiser les termes du débat autour des comités d’éthique et d’examiner le rôle joué par les maisons d’édition et l’évolution du champ éditorial dans l’exposition publique des chercheurs. Elle est aussi l’occasion de questionner l’intérêt de la conservation des carnets d’ethnographe au regard du risque d’exposition de données personnelles que représente une éventuelle saisine judiciaire des carnets de terrain.
Peur de la violence et enquête de terrain
Authors: Mohammed Marwan
Published: December 2022

Les espaces de la délinquance organisée sont structurés par des risques spécifiques plaçant les chercheur·es dans une position difficile, au croisement des dynamiques internes à ces mondes et de la pression qu’exerce sur eux et elles l’action des instances pénales. Cette tension inhérente à toute immersion dans des espaces où la violence est structurante, est ici abordée à travers une réflexion sur le sentiment d’insécurité et la peur que ce risque génère. Un risque qui produit des effets sur le recueil et la protection des données, et dont l’appréciation par le chercheur est indissociable de ses dispositions sociales et plus spécifiquement de son « capital réputationnel ».
La difficile différenciation entre recherche et expertise
Authors: Arnhold Valerie
Published: December 2022

Cet article étudie comment les tensions inhérentes à la recherche partenariale peuvent être investies, dans certains secteurs stratégiques comme le nucléaire, pour orienter la recherche publique en faveur des intérêts de certains partenaires institutionnels. Par une démarche réflexive et ethnographique, l’article analyse les interactions et la production d’écrits d’un projet collaboratif organisé dans le contexte post-Fukushima en France. Il montre comment le contrôle institutionnel procède d’une approche intégrée des activités de recherche et d’expertise, à laquelle tentent de résister les chercheur·es en distinguant ces activités par différentes stratégies.
Sortir l’histoire de son berceau judiciaire
Authors: Morsel Joseph , Noûs Camille
Published: December 2022

L’éventualité d’une destruction, par des sociologues ou des ethnologues, de leurs carnets d’enquête pour les soustraire à tout risque de perquisition et ainsi garantir l’anonymat des enquêté·es soulève pour l’historien·ne la question de la vérifiabilité des énoncés, qu’est censé assurer le recours systématique aux notes (infrapaginales ou de fin). Mais plutôt que de voir dans les procédures d’anonymisation, courantes en sciences sociales, une fragilisation de la vérifiabilité et une entrave à la réplicabilité des enquêtes, la confrontation de l’historien·ne à de telles procédures conduit à reconsidérer le lien génétique qui s’est établi entre la science historique et la vérité, à l’écart des autres sciences et à des fins idéologiques.
Le chercheur suspect et espion par association : entretien avec Roland Marchal
Authors: Marchal Roland , Laurens Sylvain , Siméant-Germanos Johanna
Published: December 2022

Cet entretien survient quelques mois à peine après la libération de Roland Marchal des prisons iraniennes, et alors que notre collègue Fariba Adelkhah est toujours détenue. Il est notamment l’occasion de revenir sur la façon dont les institutions de recherche – à travers certaines de leurs collaborations institutionnelles (armée, diplomatie, bailleurs de fonds internationaux…) – peuvent non seulement perdre en autonomie scientifique, mais mettre en danger des chercheurs, jetant le doute sur l’autonomie de leur travail. Au-delà du seul cas iranien, l’entretien aborde la position délicate des chercheurs travaillant sur des terrains réputés difficiles, dont l’expertise est régulièrement sollicitée ou censurée par les institutions pourvoyeuses de financement.
Les temporalités de la comparaison ethnographique
Authors: Clair Isabelle
Published: December 2022

À l’issue d’une enquête menée pendant près de vingt ans sur l’expérience de l’amour à la fin de l’adolescence, cet article propose une analyse réflexive des terrains réalisés dans trois espaces contrastés de la société française, ainsi que du traitement dont ces derniers ont fait l’objet au fil du temps. Pour cela, il met au jour quatre temporalités (le temps historique, le temps ethnographique, le temps comparatif et le temps biographique) qui ont pesé, de manière mêlée, sur la constitution et l’analyse du matériau – comme elles sont susceptibles de peser sur toute enquête mobilisant, de même, la comparaison ethnographique.
Construire une légitimité scientifique : les polémiques autour de la composition et de la réception de la Commission française sur le rôle de la France au Rwanda
Authors: Beaufils Mathilde
Published: December 2022

La commission Duclert, en tant que lieu de production d’un discours expert sur le rôle de la France au Rwanda dans un contexte de polémique politique et scientifique, peut être analysée comme un « lieu neutre ». Sa composition fait l’objet de nombreux débats portant sur l’éviction de « spécialistes » du Rwanda. Il s’agit alors pour les membres de cette commission de construire une légitimité scientifique. Malgré ces controverses, le rapport de la commission Duclert, du fait de la polysémie de sa forme et de ses conclusions, offre la possibilité d’un relatif consensus politique, et dès lors d’une possible marginalisation des positionnements « extrêmes » de la polémique sur le rôle de la France au Rwanda.
L’Adam paradisiaque, l’Adam pécheur et l’Adam pèlerin : essai d’interprétation de l’ Ovide moralisé xi , 1099–2995
Authors: Kretschmer Marek Thue
Published: December 2022

Cet article prend comme point de départ le constat de M. Possamaï-Pérez selon lequel Achille figure le Christ dans le livre  xii de l’ Ovide moralisé . Son travail constitue sans doute un apport considérable à la compréhension de la signification de la matière troyenne dans l’ Ovide moralisé . Cependant, aucune étude semblable n’a été faite sur la figure de Pélée. Le présent article avance l’hypothèse que l’interprétation typologique de la matière troyenne peut être étendue au livre  xi . En effet, une analyse des v. 1099–2995 de ce livre montre que les péripéties du père d’Achille figurent le destin d’Adam, de sorte qu’une double typologie s’établit : Pélée-Achille/Adam-Christ.
Allelopathy activity under laboratory, greenhouse and field conditions: A review
Authors: Sahrir Muhd Arif Shaffiq , Yusoff Nornasuha , Azizan Kamalrul Azlan
Published: December 2022

Weeds are one of the significant problems that impact agriculture production. Farmers have been using synthetic herbicides to control weed infestations in the field. However, the excessive usage of herbicides has led to various environmental concerns, including the emergence of herbicide resistant weeds. Allelopathy is an environment-friendly alternative that can control weeds. Here, we performed a systematic literature review to assess the potential and effects of allelopathy under laboratory, greenhouse and field conditions. Articles were collected by searching the SCOPUS database and guided by PRISMA. Of 371 studies identified, forty-three articles used allelopathy to control weeds under greenhouse and field conditions, with Poaceae being the prominent family studied as donor plants. Six articles reported up to 80% weed growth suppression when spraying allelopathy extract under greenhouse conditions, while mulch and soil incorporated with donor plants contributed over 50% suppression under field conditions. The findings revealed that 20 studies had conducted metabolite identification to determine the allelochemicals with phytotoxic activity against target plants. However, the mechanism of allelopathy was not thoroughly investigated. In conclusion, we found an increasing trend of allelopathy experiments conducted under greenhouse and field conditions. Furthermore, field trials should be included to validate laboratory data and to provide insight into allelochemical action and its relationship with the environment.
Study of visual SLAM methods in minimally invasive surgery
Authors: Deng Liwei , Liu Zhen , Zhang Tao , Yan Zhe
Published: December 2022

In recent years, minimally invasive surgery has developed rapidly in the clinical practice of surgery and has gradually become one of the critical surgical techniques. Compared with traditional surgery, the advantages of minimally invasive surgery include small incisions and less pain during the operation, and the patients recover faster after surgery. With the expansion of minimally invasive surgery in several medical fields, traditional minimally invasive techniques have bottlenecks in clinical practice, such as the inability of the endoscope to determine the depth information of the lesion area from the two-dimensional images obtained, the difficulty in locating the endoscopic position information and the inability to get a complete view of the overall situation in the cavity. This paper uses a visual simultaneous localization and mapping (SLAM) approach to achieve endoscope localization and reconstruction of the surgical region in a minimally invasive surgical environment. Firstly, the K-Means algorithm combined with the Super point algorithm is used to extract the feature information of the image in the lumen environment. Compared with Super points, the logarithm of successful matching points increased by 32.69%, the proportion of effective points increased by 25.28%, the error matching rate decreased by 0.64%, and the extraction time decreased by 1.98%. Then the iterative closest point method is used to estimate the position and attitude information of the endoscope. Finally, the disparity map is obtained by the stereo matching method, and the point cloud image of the surgical area is finally recovered.
A periodic boundary value problem of fractional differential equation involving $ p\left(t \right) $-Laplacian operator
Authors: Xue Tingting , Fan Xiaolin , Cao Hong , Fu Lina
Published: December 2022

The purpose of this article is to research the existence of solutions for fractional periodic boundary value problems with $ p\left(t \right) $-Laplacian operator. In this regard, the article needs to establish a continuation theorem corresponding to the above problem. By applying the continuation theorem, a new existence result for the problem is obtained, which enriches existing literature. In addition, we provide an example to verify the main result.
Aphrica supplex o el despertar propagandístico de Mazalquivir (1505)
Authors: Fernández de Córdova Álvaro
Published: December 2022

Este trabajo estudia los orígenes de la literatura propagandística sobre la campaña norteafricana impulsada por Fernando II de Aragón a inicios del siglo XVI. La crisis sucesoria castellana y la maduración del proyecto sobre el sultanato de Tremecén reactivó la campaña de Mazalquivir (1505) divulgada en Roma a través de una Laus Hispaniae que refleja por primera vez las sinergias hispano-papales sobre el nuevo Imperium Christianum anunciado por Julio II. En este contexto, las celebraciones por la toma del puerto argelino originaron un ciclo literario africano que se desarrolló en forma de epístolas, poemas y discursos pronunciados en la península ibérica y en la italiana.
El cortesano embustero, una supuesta comedia olvidada de Lope de Vega, y La española, de Cepeda
Authors: García-Reidy Alejandro
Published: December 2022

En este artículo analizo un manuscrito que supuestamente contiene una comedia de Lope de Vega titulada de El cortesano embustero y mostraré cómo en realidad es un nuevo testimonio de la comedia del dramaturgo sevillano Cepeda titulada La española. El estudio de la materialidad y del texto que presenta este manuscrito desatendido permitirá profundizar en la historia de la circulación y recepción de esta pieza teatral de Cepeda y establecer algunos fundamentos filológicos imprescindibles para una futura edición crítica de la obra.
ĬBĪ-ĬBĪDEM en la Grant Crónica de Espanya (1385). Variantes formales, cambios semánticos y funciones discursivas
Authors: Gille Johan , Enguita Utrilla José M.ª
Published: December 2022

En los estudios sobre el aragonés medieval destacan los especialistas la presencia de los adverbios pronominales derivados de ĬBĪ-ĬBĪDEM, si bien no disponemos aún de una monografía que estudie con detalle su relevancia. Con el objetivo de ir llenando ese vacío, en esta comunicación atendemos a los numerosos testimonios que proporciona la Grant Crónica de Espanya (1385), obra en aragonés patrocinada por Juan Fernández de Heredia. Analizamos en las páginas que siguen las variantes romances que presentan, su posición en la construcción oracional y las funciones con que se emplean en el texto herediano: complemento locativo pleno, complemento locativo con valor existencial, locativo figurado como sustituto de unidades léxicas y secuencias sintácticas y complemento de régimen verbal.
La Crónica del infante don Crisócalo: un libro de caballerías manuscrito en la biblioteca de Felipe II
Authors: Gonzalo Sánchez-Molero José Luis , Lucía Megías José Manuel
Published: December 2022

En el catálogo de libros que poseía Felipe II en el Alcázar de Madrid, aparece citada una copia manuscrita de la Crónica del infante don Crisócalo. Se trata de la continuación de otro libro de caballerías, Cirongilio de Tracia, un dato que permite rescatar la existencia de un nuevo libro de caballerías manuscrito castellano. No había constancia de que este libro hubiera sido escrito. Los autores, a partir de esta referencia, estudian el contexto literario y cortesano caballeresco en que esta obra se escribió y plantean cómo pudo llegar este libro de Bernardo de Vargas a la biblioteca regia.
Impact of Ujjwala Yojana Scheme and Its Effect on Behavioural Changes Among Rural Women
Authors: Selvam V.  , Ashok D.  , Rajamanoharan Indra Devi , Rajalakshmi V.  , Vidhya K.
Published: December 2022

Delivering multiple roles every single day, women are undoubtedly the backbone of any society. However, they have also been an ignored segment of the society in many parts of the world. To re-establish their rightful and distinguished status, empowerment programmes need to be started to provide a compact groundwork to encourage the inner strength and self-esteem for the rural women. This research contirubute to weaker section of the women in rural areas which uplift there standard of living through PMUJ scheme in Inida. The Government of India has initiated and implemented the scheme namely Pradhan Mantri Ujjwala Yojana (PMUJ)-Liquefied Petroleum Gas (LPG) connection helping in a big way to rural women through empowering their livelihood and transforming behavioural changes from using cow dung cake, wood, kerosene to LPG in terms of improvement in health and increase the economic productivity by saving time spent on arranging cooking needs. The Ujjwala Yojana is aimed at substituting the unclean cooking fuels regularly used in the rural India with the clean LPG. It has been stated that nearly 38% of the world's population is still dependent on traditional biomass for cooking. But, in India, the women in rural area have limited access to cooking gas. According to experts, having an open fire in the kitchen by using biomass fuels is like burning 400 cigarettes an hour. Based on this background, this descriptive research paper analyses the impact of Ujjwala Yojana scheme and its effect on transforming the livelihood and behavioural changes among rural women in three select districts in Tamil Nadu, India. The sample unit in this study consist of rural women from eight villages covering six Taluk, who received LPG connection under PMUJ for cooking their food at home. The findings of the study revealed that, there is a positive impact and behavioural changes among rural women due to PMUY scheme.
Golden Eye
Authors: Zhang Fan , Chen Wei , Zhu Yongqiong
Published: December 2022

File systems are important sources of intelligence information and digital evidence. They have long attracted the interest of researchers in recovering files that are deleted from a hard disk. Existing file recovery studies rely heavily on an operating system (OS). However, it is often encountered that OS services are not available, making existing file recovery approaches unusable. To address this issue, the authors design and implement an OS-independent file recovery algorithm named Golden Eye (GE) by targeting the EXT4 file system. Fed the raw image obtained from a (sanitized) hard disk, GE can automatically recover any designated file or even the whole EXT4 file system. GE is based on the understanding of the file disk layout of EXT4 and does not need any support from additional hardware or software. Experimental results prove the feasibility and correctness of GE. This work not only solves the OS dependency problem that most existing file recovery work suffers from but also reveals the fact that even sanitized hard disks are still at risk of leaking sensitive data.
Design and Implementation of Identity Verification Software Based on Deep Learning
Authors: Yu Runde , Zhang Xianwei , Zhang Yimeng , Song Jianfeng , Liu Kang , Miao Qiguang
Published: December 2022

Identity verification, a noncontact biometric identification technology, has important scientific significance in theoretical research and shows great practical value in national security, public safety, and finance. In view of this situation, this paper designs an identity verification software based on deep learning, which has been successfully applied to real-world applications. The central idea of the software can be summarized as follows: First, the lightweight multi-task cascaded convolutional network (MTCNN), which can learn correlations between face detection and alignment, is employed for face detection. The software then conducts face recognition with MobileFaceNet which is an efficient and lightweight neural network, reducing the hardware cost. The test results show that the software meets the design requirements and can complete the corresponding identity confirmation function.
Operational Decision-Making on Desalination Plants
Authors: Dargam Fatima C.C. , Perz Erhard , Bergmann Stefan , Rodionova Ekaterina , Sousa Pedro , Souza Francisco Alexandre A. , Matias Tiago , Ortiz Juan Manuel , Esteve-Nuñez Abraham , Rodenas Pau , Bonachela Patricia Zamora
Published: December 2022

This paper describes some of the work carried out within the Horizon 2020 project MIDES (MIcrobial DESalination for low energy drinking water), which is developing the world's largest demonstration of a low-energy sys-tem to produce safe drinking water. The work in focus concerns the support for operational decisions on desalination plants, specifically applied to a mi-crobial-powered approach for water treatment and desalination, starting from the stages of process modelling, process simulation, optimization and lab-validation, through the stages of plant monitoring and automated control. The work is based on the application of the environment IPSEpro for the stage of process modelling and simulation; and on the system DataBridge for auto-mated control, which employs techniques of Machine Learning.
Rethinking Technology-Based Services to Promote Citizen Participation in Urban Mobility
Authors: Duarte Sérgio Pedro , Pinho de Sousa Jorge , Freire de Sousa Jorge
Published: December 2022

Cities are complex and dynamic systems in which a network of actors interact, creating value through different activities. Cities can, therefore, be viewed as service ecosystems. Municipalities take advantage of digitalization to implement a service-dominant logic in urban and mobility planning and management, developing strategies with which citizens, local authorities, and other actors can create value together. While citizens are offered a better service experience, local authorities use citizens' input to improve decision-making processes. This research considers that designing an integrated service supported by an integrated information system can respond to current challenges in decision-making and information access for transport and mobility. Through a multidisciplinary methodological approach, this work proposes some guidelines to design an integrated information system to improve citizens' participation in urban planning and mobility services.
“Online Learning” Technology Solutions During the COVID-19 Pandemic
Authors: Chunkhare Milind , Jadhav Sammita
Published: December 2022

The COVID-19 outbreak has greatly forced the education systems around the world to undergo rapid change. Given today's uncertainty, it is essential to understand students' online learning experiences during the COVID-19 pandemic. Despite the fact that many studies were investigated in this area, there is limited available information about the barriers, challenges, and the difficulties students face during online learning. This paper studies the online learning platforms' utilization during the COVID-19 pandemic for students' engagement in the Medical Technology and Allied Healthcare education. This paper looks at studying the various benefits of imparting education through e-learning, identifying the challenges faced by learners, and measures the satisfaction levels of learners. From the study, it emerged that students' satisfaction index in using e-learning technologies is high for courses in Medical Technology and Allied Healthcare education.
Effect of Economic and Technological Development Zones on Green Innovation
Authors: Cheng Wenyin , Wang Qingchun , Ouyang Xin , Xie Yize , Gao Yuning , Yu Anqi
Published: December 2022

Green innovation is an effective way of solving the dilemma of the economy–environment trade-off. As an important innovation policy in China, national economic and technological development zones (NETDZs) play a significant role in promoting innovation, but empirical studies on their impact on innovation, especially green innovation, are scarce. In this study, the authors used highly disaggregated micro-level data such as patent data, industrial firm data, and customs data to examine the impact of NETDZs on green innovation. The results showed that: (1) NETDZs significantly promote green innovation, as measured by both patent quantity and patent quality; (2) the binding environmental indicators in China's five-year plan enhance the promotional effect of NETDZs on green innovation; (3) learning by importing, including through foreign direct investment and importing capital goods, is an important mechanism for the nexus between NETDZs and green innovation; and (4) compared with non-state-owned enterprises (non-SOEs), SOEs are relatively passive in terms of engaging in learning by importing.
Examining Social E-Commerce Platforms by Mediating the Effect of Perceived Usefulness and Perceived Trust Using the Technology Acceptance Model
Authors: Cai Han
Published: December 2022

In the post-COVID-19 era, promoting the healthy development of social e-commerce platforms, taking into account the coordinated development of online social networking and online consumption, enhancing the shopping and sharing atmosphere of the platform, increasing the enthusiasm of distribution members, driving consumption traffic with social traffic, and achieving low-cost publicity and promotion increase the exposure of products. The key to solving the problem is to promote consumer participation, improve user conversion, and improve customer acquisition capabilities. The study is based on the stimulus-organism-response (S-O-R) theory. It introduces the technology acceptance model (TAM) and, according to the member life cycle theory and member value mining theory, will affect consumers' social presence factors in social e-commerce shopping situations. As independent variables, perceived trust and perceived usefulness are used as mediating variables to construct a research model that shows social e-commerce affects user conversion.
Synthesis of Fatty Imidazoline from Oleic Acid with Ethylenediamine and its Characterization
Authors: Berghuis Nila Tanyela , Ali Zulfikar Fauzan
Published: December 2022

In this work, imidazoline-oleic derivative had been successfully synthesized by reacting ethylenediamine (EDA) with oleic acid (OA). The synthesis process was performed with MAOS (Microwave Assisted Organic Synthesis) and the conventional method (reflux with Dean-Stark) using xylene as a solvent was also performed as comparisons. The percentage yield of EDA-OA imidazoline was obtained from Reflux with Dean-Stark at 5 hours (90 %), and MAOS at 10 min (68,2 %). EDA-OA imidazoline then was identified by using thin-layer chromatography, and the separation method by KVC with eluent CHCl3: MeOH (9:1) with ammonium solution followed by characterization using Fourier Transform Infrared (FTIR), UV-Vis, Proton Nuclear Magnetic Resonance (1H-NMR). This study provides information regarding the comparison method for imidazoline derivative synthesis. For further research, EDA-OA imidazoline can be used as a corrosion inhibitor towards carbon steel.
Midkine ameliorates LPS-induced apoptosis of airway smooth muscle cells via the Notch2 pathway
Authors: Huang Qi-Feng , Wang Bo , Weng Yu-Qing , Deng Tang , Li Li-Hua , Qian Jin , Li Qi , Lin Kai-Wen , Sun Dong-Mei , Xu Shuang-Qin , Wang Hang-Fei , Wu Xin-Xin , Sun Yuan-Tian , Liu Xiao-Ran
Published: December 2022

Objective:

To evaluate the effect of midkine on lipopolysaccharide (LPS)-induced airway smooth muscle cells (ASMCs).

Methods:

LPS-stimulated acute lung injury model was used to analyze the effect of midkine on ASMCs in vitro. Recombinant midkine and midkine siRNA were used to investigate the role of Notch2 signaling pathway. Cell proliferation was assessed using Cell Counting Kit-8 assay. Additionally, apoptosis was measured by flow cytometry and protein and mRNA expression of midkine and Notch2 was assessed by Western blotting and qPCR, respectively. Immunofluorescence analysis was also conducted.

Results:

LPS increased the mRNA and protein expression of midkine and Notch2. Midkine silencing reduced LPS-induced midkine and Notch2 expression. In addition, midkine silencing further reduced the viability and increased apoptosis of ASMCs induced by LPS, which was attenuated by recombinant midkine.

Conclusions:

The midkine/Notch2 signaling pathway plays a regulatory role in ASMC proliferation and apoptosis in airway inflammation.
In-silico and in-vitro evaluation of docetaxel and berberine as potential p53 modulating apoptotic inducers in oral squamous cell carcinoma
Authors: Samal Smrutipragnya , Meher Rajesh Kumar , Dubey Debasmita , Mir Showkat Ahmad , Nayak Binata , Sahu Mahesh Chandra , Naik Pradeep Kumar , Rath Goutam , Swain Santosh Kumar
Published: December 2022

Objective:

To investigate the interaction of p53 with docetaxel and berberine and their anticancer activities against oral squamous cell carcinoma.

Methods:

The interaction between p53 with docetaxel and berberine was investigated and their mechanisms of action against oral squamous cell carcinoma were studied. Toxicity studies were performed to determine any toxic impact of the drugs on the vital organs of tested animals.

Results:

In silico results revealed the molecular interaction of docetaxel and berberine with p53 and the molecules were found to be potential p53 inducers. Docetaxel and berberine inhibited the proliferation of cancer cells in a concentration-dependent manner. Flow cytometry analysis revealed that docetaxel and berberine at IC50 concentrations upregulated the expression of p53 in oral squamous cell carcinoma cells, thus triggering apoptotic cell death. In addition, no toxicity was observed in the liver and kidney tissues of mice after docetaxel and berberine treatment.

Conclusions:

Docetaxel and berberine significantly suppressed the proliferation of oral cancer cells by activating p53 expression and causing apoptotic cell death. Both compounds can be potential agents for the treatment of oral cancer, with little to no toxicity at the tissue level.