bluuebunny/crossref_metadata_2025 huggingface dataset:
Indicators of cellular metabolism alterationsin patients with traumatic disease due to hypoxia, depending on a management regimen of intensive care
Authors: Matvieienko M. S. , Volkova Y. V. , Belozorov I. V. , Shamoun K. E. , Riabov O. V. , Pronin V. O.
Published: January 2022

The aim of this study was to evaluate changes in the level of erythrocyte metabolism under conditions of hypoxia in patients with traumatic disease in polytrauma depending on the components of intensive care (IC).
Materials and methods. A prospective study was carried out in 88 patients suffering from polytrauma in the period from 2015 to 2017. All the patients were divided into 2 groups, comparable by severity of trauma and condition. A special feature of the examined patients was the staged surgical correction in all cases according to the Damage Control concept.
Patients from the Control group received an intensive care according to the standard local clinical protocol in polytrauma. Patients randomized to the FDP group were treated with infusion of D-fructose-1,6-diphosphate sodium hydrate in addition to the standard care. Hemodynamic parameters and cellular metabolism indicators were monitored: on admission to the operating room, after 24 hours, on day 3, 5 and 14.
Results. The signs of hypovolemia were equally severe in both groups on admission to the operating room. The FDP group demonstrated more rapid stabilization of hemodynamics and improved myocardial contractility at the 3rd day of IC.
The monitoring of acid-base balance and carbohydrate metabolism showed the presence of compensated metabolic acidosis and energy deficiency. High indexes of lactate/pyruvate indicated a sharp imbalance in the ratio of aerobic/anaerobic metabolic processes. The analysis of ATP dynamics displayed impaired mitochondrial ATP production and inhibition of the glycolytic pathway of energy release.
Conclusions. Complementary systemic inflammatory response with the elevation of lactate level by the 5th day occurred in patients with traumatic disease who underwent staged surgical correction. Optimization of intensive care resulted in a faster restoration of the balance between aerobic and anaerobic metabolic processes, an increase in the level of ATP and the rate of 2,3-DPG production in erythrocytes contributing to adequate oxygen supply to the tissues, supporting cellular respiration and preventing the development of oxidative tissue damage, as well as helped to maintain compensatory mechanisms and reduce cellular hypoxia ensuring adequate metabolism of vital organs.
The impact of concomitant anemic syndrome on the clinical course of coronary artery disease
Authors: Konovalova M. O. , Mykhailovska N. S.
Published: January 2022

The presence of comorbid pathology negatively affects the prognosis of patients with coronary artery disease (CAD). Today it is important to clarify the features of CAD on the background of concomitant anemia and identify the main risk factors for complications to improve the tactics of this category of patients.
The aim. To investigate the influence of concomitant anemic syndrome on the clinical course of coronary artery disease, frequency and features of the main cardiovascular events.
Materials and methods. The study involved 91 patients with coronary artery disease (42 men and 49 women, age – 70 (49; 93)). All patients were divided into 2 groups: the main group (n = 46) consisted of patients with coronary artery disease with iron-deficiency anemia, the comparison group (n = 45) – patients with coronary artery disease without iron-deficiency anemia. The study of the main cardiovascular events took into account re-hospitalization due to arrhythmic disorders, progression of heart failure (HF), CAD destabilization within the observed period (1 year), as well as death from cardiovascular causes. The data analysis was performed using Statistica 13.0.
Results. During the year, 42 non-fatal cardiovascular events were noted in patients of both groups, however in the main group their total number was 30 (67 %) versus 12 (27 %) in the comparison group (χ2 = 13.603; P < 0.05). The presence of concomitant anemia in CAD patients significantly increased the relative risk of re-hospitalizations (RR = 1.9; 95 % CI 1.230–3.112; P < 0.05). Among the reasons for hospitalization in the main group, HF decompensation prevailed – 17 (57 %) patients, unstable angina – 7 (23 %), arrhythmic disorders – 6 (20 %); in the comparison group, among the reasons for re-hospitalization, 7 (57 %) had HF decompensation, 3 (25 %) had unstable angina, and 2 (17 %) cases had arrhythmic disorders. In total, 9 (19.5 %) deaths were recorded in the main group, while in the comparison group 1 (2.2 %) death was recorded during the year (χ2 = 6.995; P < 0.05). The presence of concomitant anemia in patients with CAD increases the risk of fatal outcome by 8.8 times (RR = 8.8; 95 % CI 1.162–66.685; P < 0.05). The presence of moderate anemia in patients with CAD significantly increases the incidence of combined critical events by 39 % during the year of follow-up compared with mild anemia (χ2 = 12.843; P < 0.05).
Conclusions. The presence of concomitant anemia is associated with a worsened prognosis for patients having coronary artery disease due to an increased risk of non-fatal cardiovascular events that require re-hospitalization during the year of observation, and an increased incidence of death. Increasing severity of anemia is associated with an increase in the frequency of the combined critical event during 1 year of follow-up.
Perioperative metabolism in patients with secondary hyperparathyroidism and methods of its correction
Authors: Denysenko A. I. , Chernii V. I.
Published: January 2022

It is important to study changes in metabolism in patients with secondary hyperparathyroidism (SHPT) during parathyroid surgical interventions (PTSI), as well as to search for ways to correct them.
Aim. To study metabolism in patients with SHPT with PTSI and assess the possibilities of its correction.
Materials and methods. The study was prospective, not randomized. We studied 135 patients with SHPT with end-stage chronic renal failure who underwent PTSI (72 men and 63 women, aged from 19 to 73 years). Preoperative risk ASA III–IV. General anesthesia using the inhalation anesthetic sevoflurane and the narcotic analgesic fentanyl in low-flow mechanical ventilation. Operational monitoring was complemented by the use of indirect calorimetry. In group I (n = 70), the metabolic rate (MR) and basal metabolism rate (BMR) were determined against the background of standard intensive therapy. In group II (n = 65) – target metabolic rate (TMR) and the metabolic disorders (MD) were additionally determined, and intensive therapy was supplemented with glucocorticoids.
Results. The baseline MR in both groups were low, close to BMR. The MR of patients in group I remained low during the entire PTSI (P < 0.05). In group II, from the stage of removal of the parathyroid glands, a steady increase in the MR, with a significant excess of the baseline MR and BMR (P < 0.05), was noted. TMR decreased while exceeding the MR. Group II patients woke up and were transferred to the ward faster compared to group I, and nausea and vomiting were 2.5 times less frequent (9.2 % in group II, 22.9 % in group I). 12 hours after PTSI, feeling of pain, according to the VAS scale, was lower than in group I (P < 0.05). During the day after PTSI, the indicators of the acid-base state of the venous blood of both groups did not change significantly, and the level of ionized calcium decreased (P < 0.05), which required additional intravenous administration of 10 % calcium gluconate.
Conclusions. Perioperative energy monitoring makes it safer to carry out PTSI in patients with SHPT. Additional definition of the TMR and the MD allows for more efficient construction of intensive therapy.
Synthesis and study of the anticancer activity of some new 7H-[1,2,4]triazolo [3,4-b][1,3,4]thiadiazines
Authors: Myrko I. I. , Chaban T. I. , Ohurtsov V. V. , Drapak I. V. , Matiichuk V. S.
Published: January 2022

The problem of finding effective low-toxic anticancer agents is one of the most important in modern medicine and pharmacy. Despite a large selection of anticancer drugs and a variety of mechanisms of their action, the effectiveness of existing drugs continues to be insufficient. Among the numerous natural and synthetic heterocyclic compounds that exhibit anticancer activity, 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine derivatives, which are able to initiate different pathways of tumor cell death. Based on this, the synthesis of new derivatives of this class of compounds and the study of their anticancer properties is relevant.
The aim of the work is to synthesis of new 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and study their anticancer activity.
Materials and methods. It was used methods of organic synthesis, physical and chemical methods of analysis organic compounds (1H NMR spectroscopy, elemental analysis).
Results. In order to obtain new 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines, the interaction implemented of 4-amino-4H-[1,2,4]triazole-3-thiols with the corresponding bromoacetophenones. The reaction proceeds by heating the above reagents in alcohol with the closure of the thiadiazine ring and the formation of 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine systems. The structure of all synthesized compounds was confirmed by 1H NMR spectroscopy and elemental analysis data.
The study of the anticancer activity of the synthesized compounds was carried out in the framework of the international scientific program DTP (Developmental Therapeutics Program) of the National Cancer Institute (NCI, Bethesda, Maryland, USA). It was found that the synthesized compounds exhibited different levels of anticancer activity. The most active among the tested substances was compound 3j with an average GP value of 28.73. The most sensitive to it were the lines of melanoma MDA-MB-435 and SK-MEL-2, kidney cancer A498 and RXF 393, CNS cancer SNB-75, and non-small cell lung cancer NCI-H522. The secondary stage of studies of this compound confirmed its high anticancer activity against most cancer cell lines.
Conclusions. As a result of the interaction of 4-amino-4H-[1,2,4]triazole-3-thiols with the relevant bromoacetophenones, a series of new triazolo[3,4-b][1,3,4]thiadiazines was not described in the literature was synthesized. Testing the synthesized compounds for the antitumor activity made it possible to isolate 1 highly active compound with a pronounced anticancer effect, which in terms of activity approaches or exceeds the known drugs 5-fluorouracil (5-FU) and cisplatin, as well as an anticancer agent, curcumin.
Parameters of obtaining tincture from underground organs of Sanguisorba officinalisand study its biological activity
Authors: Oproshanska T. V. , Khvorost O. P.
Published: January 2022

The aim of the work is to experimentally determine the optimal parameters for obtaining a tincture of rhizomes with roots of Sanguisorba officinalis and to investigate its antimicrobial and antioxidant activity.
Materials and methods. Rhizomes with roots of Sanguisorba officinalis were harvested in autumn 2019. When establishing the optimal parameters of the technology of obtaining tincture, the evaluation criterion was the number of the sum of polyphenols and the amount of hydroxycinnamic acids, which were determined by spectrophotometric method according to the methods of the State Pharmacopoeia of Ukraine 2.0. Antimicrobial activity was studied by agar diffusion and serial dilutions, antioxidant – in vitro using a stable radical 2,2-diphenyl-1-picrylhydrazyl (2,2-diphenyl-1-picrylhydrazyl – DPPH).
Results. The optimal parameters for obtaining a tincture of rhizomes with roots of Sanguisorba officinalis was extraction method maceration at room temperature, raw material-finished product ratio 1:5, time 48 hours, extractant 50 % ethyl alcohol, the number of polyphenols, and the number of hydroxycinnamic acids in terms of dry raw materials not less than 4.0 % and 1.5 % respectively. The resulting tincture exhibits antimicrobial activity against microorganisms Bacillus subtilis ATCC 6633 (growth retardation 26.40 ± 1.04 mm), Staphylococcus aureus ATCC 25923 (growth retardation 24.60 ± 0.68 mm) and Pseudomonas aeruginosa ATCС 27853 (growth retardation 23.60 ± 0.68 mm) and at a dose of 0.02 ml showed antioxidant activity at the level of 70 %.
Conclusions. The parameters of obtaining a tincture of rhizomes with roots of Sanguisorba officinalis were determined and its antimicrobial and antioxidant activity was studied.
Wczesnośredniowieczne grodzisko w Dusinie, pow. gostyński, woj. wielkopolskie w świetle ponownej analizy archeologicznej
Authors: Mizerka Jagoda
Published: January 2022

The article presents the results of another archaeological analysis carried out on materials from an early medieval settlement in Dusina in southern Greater Poland. The data obtained during the excavations, during the millennium research, prompted the recognition of the settlement as the oldest motte-type object in Poland. During the verification of the old findings, the ceramic material and the stratigraphic situation were re-analyzed, radiocarbon dating was made, and historical and cartographic data were used to confirm the chronology of the stronghold as well as the course of events that led to severe damage and disturbance of the original appearance of the stronghold. A contour plan and a model of the terrain were also prepared.
Experimental identification of the subjective reception of external stimuli during wheelchair driving
Authors: Chwalik-Pilszyk Gabriela , Dziechciowski Zygmunt , Kromka-Szydek Magdalena , Kozień Marek S.
Published: January 2022

The aim of this article is identification of the subjective reception of external stimuli during wheelchair driving by analyses of vibration signals obtained from measurements. The identification concerns the impact of vibrations generated during crossing various types of pavements on the discomfort feelings of the selected human body parts (mainly the spine). The identification used the measurements of the whole body vibrations received by the user of the wheelchair. The research focuses mainly on the analysis in the frequency ranges corresponding to the vibration resonance of the spine. It is because respondents of the conducted surveys selected the spine as one of the most sensitive parts of the body.
Semantische Wissensnetze – vertrauenswürdige KI für innovative Businessanwendungen
Authors: Munk Katharina
Published: January 2022

Semantische Software-Technologien verwandeln große Mengen strukturierter und unstrukturierter Daten zu computerlesbaren und computerverwertbaren Wissensnetzen. Aufbau und Pflege der Wissensnetze gelingen im agilen Zusammenspiel zwischen Mensch und Computer. Mit angepassten Editoren, Natural Language Processing, semantischer Klassifikation und selbstlernenden Prozessen reifen sukzessive und zunehmend Kontext- und Textverständnis.

Solche Wissensnetze liefern erklärbare und nachvollziehbare Resultate. Sie sind für Forschung und Unternehmen jeder Branche von großem Wert und öffnen die Tür für innovative Anwendungen sowohl unternehmensintern als auch für Kunden: Beispiele sind Redaktionssysteme und Produktinformationssysteme mit inhaltlicher und formaler Unterstützung für neue digitale Informationsdienste sowie -Produkte, 360°-Input für Business-Entscheidungen und Suche und dynamische Aggregation semantischer Zusammenhänge im Bestandscontent.
Border Disputes: Religious Adjudication Along the Private/Public Divide
Authors: Aronson Ori
Published: January 2022

The article uses Israel’s volatile jurisdictional dynamics of the past two decades concerning access to religious community justice, as a telling case for examining the way legal pluralism is deployed along the public–private divide. The Israeli case exhibits a complex combination of an ostensibly liberal democratic regime, a commitment to a particularistic ethno-national political project, structural entanglements of state and religion against the backdrop of an unsettled constitutional order, and an historically diffuse mode of often-illiberal normative ordering within its diverse religious communities. All this provides a rich backdrop for various strategies by communal and institutional elites seeking to consolidate power, legitimacy, and authenticity in their often mutually-reliant jurisdictional projects. The article explores several salient episodes from Israel’s religious jurisdiction dynamics, focusing for purposes of analytical clarity on the case of Jewish orthodox legality. The analysis uncovers the main strategies stakeholders resort to, and shows how agency flows in different ways, with the choices of each player affecting the possibilities of the others. The institution at the arguable top of the system—the Supreme Court—is shown to be often devoid of effective means of elucidating, let along imposing, a coherent vision for a fragmented jurisdictional field. Conceptually, the judicial forum is revealed as the locus of an ongoing, uneasy engagement among normative imaginaries in a sometimes-competitive, sometimes-collaborative negotiation over coherence, tolerance, authority, and legitimacy.
Solving One-Side Polarization: Supreme Court Polarization and Politicization in Israel and the U.S.
Authors: Porat Iddo
Published: January 2022

The Israeli Supreme Court has become increasingly polarized between liberal and conservative judges. This phenomenon is relatively new to the Israeli Supreme Court and follows the much older and more well-known example of the U.S. Supreme Court. This article surveys both U.S. and Israeli court polarization and shows the history, reasons, and special features of polarization of both courts, including the important differences between them. It also adds a distinction to existing literature on court polarization—the distinction between court polarization and politicization, and especially the distinction between “regular” polarization and “one-side” polarization. Regular court polarization happens when the court is divided roughly equally between the two main political contenders (usually between right and left). One-side polarization happens when there is a clear advantage to one side of the political map in the make-up of the court. The current U.S. Supreme Court, with six conservative justices and only three liberal justices, is an example of one-side court polarization that is tilted to the right. The current Israeli Supreme Court (as of the writing of these lines) is an example for one-side court polarization tilted to the left; there are 10 liberal judges and only five conservative judges on the court. The article’s main argument is that one-side court polarization presents a particularly vexing problem for the legitimacy of the court, even more so than “regular” polarization. The article concludes with a survey of possible solutions to help Israel retract itself from one-side court polarization.
Light activation of 3D-printed structures: from millimeter to sub-micrometer scale
Authors: Jeong Hoon Yeub , An Soo-Chan , Jun Young Chul
Published: January 2022

Three-dimensional (3D) printing enables the fabrication of complex, highly customizable structures, which are difficult to fabricate using conventional fabrication methods. Recently, the concept of four-dimensional (4D) printing has emerged, which adds active and responsive functions to 3D-printed structures. Deployable or adaptive structures with desired structural and functional changes can be fabricated using 4D printing; thus, 4D printing can be applied to actuators, soft robots, sensors, medical devices, and active and reconfigurable photonic devices. The shape of 3D-printed structures can be transformed in response to external stimuli, such as heat, light, electric and magnetic fields, and humidity. Light has unique advantages as a stimulus for active devices because it can remotely and selectively induce structural changes. There have been studies on the light activation of nanomaterial composites, but they were limited to rather simple planar structures. Recently, the light activation of 3D-printed complex structures has attracted increasing attention. However, there has been no comprehensive review of this emerging topic yet. In this paper, we present a comprehensive review of the light activation of 3D-printed structures. First, we introduce representative smart materials and general shape-changing mechanisms in 4D printing. Then, we focus on the design and recent demonstration of remote light activation, particularly detailing photothermal activations based on nanomaterial composites. We explain the light activation of 3D-printed structures from the millimeter to sub-micrometer scale.
Structure and properties of two new heteroleptic bismuth(III) dithiocabamates of the general composition Bi(S2CNH2)2X (X = Cl, SCN)
Authors: Teske Christoph Ludwig , Terraschke Huayna , Mangelsen Sebastian , Bensch Wolfgang
Published: January 2022

The title compounds were prepared by precipitation from acidic solutions of the reactants in acetone/water. Bi(S2CNH2)2Cl (1) crystallizes in the non-centrosymmetric trigonal space group P32 with a = 8.6121(3) and c = 11.1554(4) Å, Z = 3; Bi(S2NH2)2SCN (2) in P21/c (monoclinic) with a = 5.5600(2), b = 14.3679(5), c = 12.8665(4) Å, and β = 90.37(3)°. In the crystal structure of 1 Bi3+ is in a sevenfold coordination of two bidentate and one monodentate S2CHNH2
− anions with an asymmetric coordination pattern of five Bi–S and two Bi–Cl− bonds. The linkage of these polyhedra via common Cl–S edges leads to a 1D polymeric structure with undulated chains propagating in the direction [001]. These chains are linked by strong and medium strong hydrogen bonds forming the 3D crystal structure. In the crystal structure of 2 the Bi3+ cation is in an eightfold coordination. The polyhedron can be described as a significantly distorted tetragonal anti-prism, capped by an additional S atom. Two of these prisms share a common quadrilateral face to form a “prism-double” (Bi2S10N2). These building units are linked by common edges, and the resulting 1D infinite angulated chains propagate along [100]. By contrast to organo-dithiocarbamate compounds, where C–H···X bridges are dominant, the interchain connections in the crystal structures of 1 and 2 are formed exclusively via N–H···S, N–H···Cl, and N–H···N interactions, generating the 3D networks. A significant eccentricity of the Bi3+ cation in the crystal structures of both complexes is observed. Both compounds emit light in the orange range of the electromagnetic spectrum.
Grounded Theory of Asian American Activists for #BlackLivesMatter
Authors: Litam Stacey Diane Arañez , Chan Christian D.
Published: January 2022

A grounded theory study was employed to identify the conditions contributing to the core phenomenon of Asian American activists (N = 25) mobilizing toward thick solidarity with the Black Lives Matter (BLM) movement in 2020. The findings indicate achieving a collective oppressed identity was necessary to mobilize in thick solidarity with the BLM movement and occurred because of causal conditions: (a) experiences of COVID-19–related anti-Asian discrimination, and (b) George Floyd’s murder. Non-action, performative or unhelpful action, and action toward thick solidarity were influenced by contextual factors: (a) alignment with personal and community values, (b) awareness and knowledge, and (c) perspectives of oppression. Mobilization was also influenced by intervening factors, which included affective responses, intergenerational conflict, conditioning of “privileges” afforded by White supremacy, and the presence of organized communities. Mental health professionals and social justice advocates can apply these findings to promote engagement in the community organizing efforts of Asian American and Pacific Islander communities with the BLM movement, denounce anti-Blackness, and uphold a culpability toward supporting the Black community.
Caring About (COVID-19 Related) Social Issues Signals Trustworthiness: Direct and Conceptual Replication of Zlatev (2019)
Authors: Dorrough Angela R. , Bick Nathalie , Bring Lukas , Brockers Caroline , Butz Charlotte , Schneider Iris K.
Published: January 2022

With three convenient samples (n = 1,087) and one sample representative for the German population in terms of age and gender (n = 210), we replicate research by Zlatev (2019) showing that perceived benevolence-based and perceived integrity-based trustworthiness increase with a target’s level of caring about a social issue. We show that these results generalize to various issues ranging from environmental issues (i.e., installation of wind turbines in the North Sea) to issues related to the COVID-19 pandemic (i.e., online teaching to prevent the spread of the virus). Furthermore, we provide initial behavioral evidence for this effect by showing that transfers in a trust game increase with a target’s caring about a social issue. All results are robust for age, gender, and social issue. To provide best estimates for the effect of a target’s level of caring on perceived trustworthiness, we report results of three mini meta-analyses including our findings as well as the findings of the original research. Policy implications are discussed.
Unusual hypocalcaemia in breast cancer relapse with multiple bone metastasis
Authors: Darawshi Said , Darawshi Mahmoud , Daoud Naccache Deeb
Published: January 2022

Severe hypocalcaemia in breast cancer with bone metastasis is a rare finding usually associated with an advanced stage of the disease. We report a case of a 45-year-old woman with a history of local ductal carcinoma in situ (DCIS) of the breast, who presented with muscle tremors and general weakness. Hypocalcaemia was evident, with a positive Chvostek sign and a serum calcium level of 5.9 mg/dL (1.47 mmol/L), phosphorus 5.9 mg/dL (normal range: 2.3–4.7 mg/dL) with normal levels of albumin, magnesium and parathyroid hormone. High oral doses of alpha calcitriol and calcium with i.v. infusion of high calcium doses were instituted, altogether sufficient to maintain only mild hypocalcaemia. A whole-body CT revealed bone lesions along the axial skeleton. A biopsy from a bone lesion revealed a metastasis of breast carcinoma. With this pathological finding, leuprolide (GNRH analogue) and chlorambucil (alkylating agent) were initiated, followed by prompt tapering of infused calcium down to full discontinuation. Serum calcium was kept stable close to the low normal range by high doses of oral alpha calcitriol and calcium. This course raises suspicion that breast metastases to the skeleton caused tumour-induced hypocalcaemia by a unique mechanism. We assume that hypocalcaemia in this case was promoted by a combination of hypoparathyroidism and bone metastasis.

Learning points

Severe hypocalcaemia can a presenting symptom for breast cancer relapse.
The Process of Deterioration of Liberal Democracy in the Visegrad Group Countries: Institutional Perspective
Authors: Kubas Sebastian
Published: January 2022

Contemporary changes of liberal democracy affect different countries of the world. The Czech Republic, Hungary, Poland and Slovakia, known as the Visegrad Group countries (V4), are among them. Although the countries seemed to be on a good way to consolidated democracy, about a decade ago the first symptoms of deterioration of liberal democracy became apparent. In the text, attention is focused on the institutional level, which should resist certain challenges in mature democracies. The institutions in V4 were weak and liable to be subordinated by strong political leaders and populist parties, and not strong enough to fight off illiberal tendencies. The analysis reveals that Poland and Hungary were more prone to compromise liberal democratic achievements, while the Czech Republic and Slovakia less so. This paper answers the questions of the institutional causes behind the deterioration of liberal democracy and the effects it brings.
Mustard surgery three months after a covid-19 infection: a case report
Authors: Arredondo Ilen Corrales , Mario Naranjo Ugalde C Alfredo , Ceruto Ortiz Lais Angélica , Escobar Bermúdez Yudith , López Rodríguez Pedro Rolando
Published: January 2022

Introduction: This past year, on a global scale, since 2019, public health warnings have gone off because of the recent epidemiological crisis set of the Covid-19 pandemic. This pandemic holds responsibility for millions of infections, manifesting broadly in its clinical presentation, which ranges from asymptomatic carriers to respiratory failure, myocardial pathology and death; increasing the rates of hospitalization. Pediatric patients are at high risk of contracting the disease including those with congenital cardiomyopathy that are in need of surgical intervention in order to survive. Objective: Show that there exists an opportunity for elective surgical treatment and short term and medium term recovery in these patients in spite of respiratory and cardiovascular sequelae. Case presentation of an eleven-month infant diagnosed with Transposition of the Great Vessels, who after three months of idleness for having tested positive for Covid-19, received definitive surgical care for the initial diagnosis. Results: The perioperative strategy was based in the probable sequelae due to the infection. There are not respiratory complications like consequence for the previous lung injury. The auriculoventricular dysfunctional immediate post-operative was related with the surgical technique. Conclusion: A period no less than three months could be offer security for surgery using extracorporeal circulation in pediatric patients who suffered covid-19. Patient with favorable post-op prognosis resulting from the work of a multi-disciplinary team that met all challenges of the complications inherent in the post-operative period following a complex cardiovascular surgery along with those of a potentially fatal virus.
The Practice of Fulfilling the State Order by Private Industrial Enterprises at the Beginning of the XX Century (On the Example of the “Trade and Industrial Society of Alafuzov’s Factories and Plants”)
Authors: Arsentyev Viktor M. , Makushev Andrey E.
Published: January 2022

Introduction. One of the priorities of economic policy in imperial Russia has traditionally been to ensure the effective performance of functions and the satisfaction of the military-strategic needs of the state. At the same time, the most important instrument for the implementation of this kind of policy was the system of state orders. At the beginning of the XX century it was a key component of the state’s life support system. Methods. The study was carried out on the basis of the principles of historicism, objectivity and consistency, the use of which in aggregate made it possible to interpret the available information on the topic as fully and deeply as possible, to consider the object of research, taking into account the peculiarities of the historical environment in conjunction with a wide range of external factors. To solve the set tasks, elements of the methods of historical and legal analysis were used, which made it possible to consider the object of research in the context of the development of Russian legislation. Results. On the basis of materials from archival files, regulatory legal acts, as well as data from published sources, the process of making state supplies to the military department was analyzed on the example of a separate industrial enterprise – “Trade and Industrial Society of Alafuzov’s Factories and Plants”. In the context of studying the practice of interaction between the management of Alafuzov’s company and government agencies, the authors consider the key features of the organization of the system for fulfilling a government order for the supply of industrial products, and also identifies the main difficulties that arose in the course of its implementation. Discussion and Conclusion. The study showed that the execution of state supplies by Alafuzov’s factories was fraught with a number of difficulties. The urgency of fulfilling orders required the mobilization of additional material and labor resources, complicating the process of managing a rather extensive and diversified industrial complex, requiring additional efforts, knowledge and abilities from representatives of the management level. The main part of the difficulties in the execution of contracts was associated not so much with the organization of the production and labor process, but with the interaction with the departments responsible for the acceptance of the supplied products. On the example of Alafuzov’s factories, it is possible to see inconsistency in the activities of individual structural links of this system, which gave rise to a number of difficulties for the executors of the state order. The reasons for this kind of difficulties were, on the one hand, failures in the operation of the mechanism for accepting goods when organizing state supplies, on the other hand, factors of a subjective nature, generated primarily by insufficient competence of responsible persons.
Regions of the North-West of Russia: Analysis of the Conditions for the Implementation of Social Innovation
Authors: Soloveva Tatiana S.
Published: January 2022

Introduction. International experience shows that social innovation is an important tool for regional development, although this type of innovation is a relatively new phenomenon for Russia. On the basis of the research conducted, the article analyzes the conditions for the implementation of social innovation which has a significant potential to meet the challenges of territorial development.

Materials and Methods. Based on materials from open sources, as well as on an expert survey conducted by the Vologda Research Center of the Russian Academy of Sciences with the direct participation of the author, the conditions for the implementation of social innovation prevailing in the constituent entities of the Northwestern Federal District of the Russian Federation were analyzed in the context of legal, infrastructural, economic, and socio-cultural components. Using the results of the expert survey, a quantitative assessment of the level of development of the conditions for the implementation of social innovation was given. The main barriers preventing the reproduction of social innovation within the territory under consideration were revealed.

Results. The study has revealed that in the regions of the Northwestern Federal District the conditions for the implementation of social innovation are at the stage of active development: infrastructure and legislation are being formed; financial, tax and property support is being provided; educational programs are being implemented. The study has also shown that there are a number of problematic aspects associated with the underdevelopment of the regulatory framework, with the lack of Centers for innovation in the social sphere in a number of constituent entities, with the limited availability of some financial instruments, with low social and innovative activity of people, etc.

Discussion and Conclusion. The results obtained are supported by other studies, which substantiates the need for policy adjustment towards improving the relevant regulatory framework, economic conditions, infrastructure, and socio-cultural environment. The research materials can be used by regional authorities when making managerial decisions to support social innovation; they can also be useful for further studies within the framework of the issues under consideration.
Fatores intervenientes na qualidade de vida docente durante a pandemia da COVID-19
Authors: Santana Leni De Lima , Ramos Tangriane Hainiski , Ziesemer Nadine De Biagi , Carvalho Edivane Pedrolo Telma Pelaes de , Pedrolo Edivane
Published: January 2022

A pandemia da COVID-19, declarada pela Organização Mundial da Saúde, em 2020, impôs à população mudança de posturas e adaptação nos modos de vida em todos os contextos. No cenário acadêmico, resultou na suspensão das atividades presenciais, na mudança de metodologias de ensino e na organização do trabalho, o que pode influenciar a qualidade de vida da população. Objetivo: identificar os fatores intervenientes na qualidade de vida dos docentes de uma instituição educacional pública federal brasileira durante a pandemia. Método: estudo descritivo, de abordagem qualitativa realizado com 20 professores do ensino Básico, Técnico e Tecnológico. Os dados foram coletados de forma remota, nos meses de setembro a dezembro de 2020, por meio de entrevistas semiestruturadas processadas por meio do Software Iramuteq®. Resultados: o estudo evidenciou que a pandemia da COVID-19 interferiu na qualidade de vida da população estudada. Como efeitos negativos observaram-se: sobrecarga de trabalho; dificuldades com as mudanças de rotinas e com as adaptações tecnológicas; desgaste relacionado à preocupação com a qualidade e o processo ensino-aprendizagem e impactos na saúde física e mental. Como fatores positivos foram identificados: aproximação familiar e autoconhecimento. Conclusões: o estudo identificou fatores intervenientes na qualidade de vida dos participantes que impactam de forma positiva e negativa no âmbito individual, familiar e profissional.
Perspectiva estudiantil sobre el plan de estudios de la carrera de Sociología de la Universidad Nacional de Costa Rica
Authors: Chaverri Chaves Diego , Redondo Ríos María José , Ruiz Delgado Daniel
Published: January 2022

Este artículo muestra una investigación cuantitativa sobre el plan de estudios de la Escuela de Sociología de la Universidad Nacional, la cual emprendió la actualización de su currículo escolar; para tal efecto se tomaron las valoraciones por parte de la comunidad estudiantil que cursaba de tercero hasta sexto año de la carrera, para un total de 137 estudiantes. Dicho análisis se basó en un instrumento que abordó las cinco áreas del plan de estudio, a saber: 1) Realidad Social, 2) Teoría Sociológica, 3) Epistemología y Metodología, 4) Técnica e Instrumental y 5) Optativa; medidas a través de una escala Likert y una pregunta abierta para capturar otros aspectos afines. Los principales hallazgos resaltan que el rendimiento del programa de estudios no es homogéneo para sus estudiantes, pues muestra disparidades en las calificaciones asignadas, además, se observa que estudiantes de los últimos niveles están menos complacidos con su malla curricular, en comparación a estudiantes de niveles previos. Finalmente, en la pregunta abierta, la población estudiantil tiende a brindar sugerencias para mejorar, que disconformidades, lo que resalta la importancia de atender la calidad de la enseñanza y los procesos pedagógicos y andragógicos. A partir de los resultados obtenidos se identifican dificultades para separar la apreciación del plan de estudios de la valoración de la planta docente, también se recomienda; reestructurar y delimitar con mayor claridad las áreas de dicho plan, estimular y acompañar la formación didáctica del personal docente en la implementación de la carrera e integrar de manera más constante los aspectos teóricos y prácticos en la formación educativa.
Capitalismo de plataformas, producción y consumo de música: el caso de Spotify
Authors: Masís González Tadeo
Published: January 2022

En el marco de los recientes cambios tecnológicos y económicos mediados por un capitalismo algoritmizado, este trabajo estudia la transformación que supone la entrada de la plataforma Spotify en la industria musical, así como sus implicaciones en cuanto al consumo y la producción de la música. Particularmente, se incluyen consideraciones para el caso particular de América Latina. Este análisis supone una revisión de los cambios recientes en la economía digital de la música a través de la noción de mundos del arte. Se evidenció el surgimiento de un nuevo actor en la industria de la música que va a asumir roles como la distribución de obras musicales y la curaduría artística, alterando así las redes de cooperación y dependencia en la industria de la música. Estas transformaciones no ocurren únicamente a una escala global, sino que pueden tener efectos potenciales para el caso latinoamericano.

Palabras clave: industria cultural; economía cultural; sociología del arte; cambio tecnológico; capitalismo
Modelo EBAP: Caracterización y evolución de los enfoques de alfabetización visual de la Etapa Básica de Artes Plásticas: 1985-2017
Authors: Villalobos Ramírez Susana
Published: January 2022

La Etapa Básica de Artes Plásticas es un proyecto de Acción Social de la Universidad de Costa Rica, el cual procura estimular el potencial creador para la exploración de las aptitudes y habilidades en el campo de las Artes Visuales. Este texto muestra parte de los resultados de la investigación “Análisis del proceso de alfabetización visual del proyecto Etapa Básica de Artes Plásticas”. Este consistió en analizar las estrategias didácticas aplicadas por el proyecto durante su trayectoria, a partir de un marco referencial entre la ejecución durante sus diferentes etapas de desarrollo y su correlación con modelos didácticos de las artes. En virtud de un rastreo de datos, análisis bibliográfico y entrevistas semiestructuradas, se categorizaron los procesos didácticos desarrollados con las comunidades. En relación con la aproximación al concepto de alfabetización visual, se procedió a la revisión de textos sobre propuestas del tema y modelos de educación artística. Se concluye que el enfoque didáctico del proyecto es híbrido, contextual y expansivo. Su principal atributo es la elasticidad, adaptación al contexto y transferencia de conocimientos tácitos. Palabras clave: alfabetización visual; comunidad; didáctica de las artes visuales; arte comunitario; educación artística
Menjaga Sastra Sunda, Menempuh Jalan Spiritualitas Berbeda: Kontribusi Ajip Rosidi terhadap Warisan Karya-karya Haji Hasan Mustapa
Authors: Rohmana Jajang A
Published: January 2022

Sundanese people lost one of the main guardians of their culture, Ajip Rosidi (1938-2020). He is a writer who has a great contribution in the treasure of Indonesian and regional literature. One of his important contributions is preserving the legacy of the works of Haji Hasan Mustapa (1852-1930), the greatest Sundanese poet who lived during the colonial period. This study focuses on Ajip’s contribution to Hasan Mustapa’s works. The source is Ajip’s publications relating to Hasan Mustapa over a period of more than 50 years (1960-2017). Through a intertextual approach, this study shows that Ajip’s contribution to the disclosure of Hasan Mustapa’s identity and the legacy of his works from the 19th century can be seen from a number of efforts he did: trace and collect the legacy of Hasan Mustapa’s works; transcribe and translate, publish, and provides an overview of aspects of Sundanese literature. Ajip tries to strengthen Hasan Mustapa’s position in Sundanese literature, although finally both of them take on differently spirituality way. Hasan Mustapa takes on the way of philosophical mysticism, while Ajip chooses to practise his religion which influenced with modernist Islamic teaching.
Breed recognition and estimation of live weight of cattle based on methods of machine learning and computer vision
Authors: Bezsonov Oleksandr , Lebediev Oleh , Lebediev Valentyn , Megel Yuriy , Prochukhan Dmytro , Rudenko Oleg
Published: January 2022

A method of measuring cattle parameters using neural network methods of image processing was proposed. To this end, several neural network models were used: a convolutional artificial neural network and a multilayer perceptron. The first is used to recognize a cow in a photograph and identify its breed followed by determining its body dimensions using the stereopsis method. The perceptron was used to estimate the cow's weight based on its breed and size information. Mask RCNN (Mask Regions with CNNs) convolutional network was chosen as an artificial neural network.
To clarify information on the physical parameters of animals, a 3D camera (Intel RealSense D435i) was used. Images of cows taken from different angles were used to determine the parameters of their bodies using the photogrammetric method.
The cow body dimensions were determined by analyzing animal images taken with synchronized cameras from different angles. First, a cow was identified in the photograph and its breed was determined using the Mask RCNN convolutional neural network. Next, the animal parameters were determined using the stereopsis method. The resulting breed and size data were fed to a predictive model to determine the estimated weight of the animal.
When modeling, Ayrshire, Holstein, Jersey, Krasnaya Stepnaya breeds were considered as cow breeds to be recognized. The use of a pre-trained network with its subsequent training applying the SGD algorithm and Nvidia GeForce 2080 video card has made it possible to significantly speed up the learning process compared to training in a CPU.
The results obtained confirm the effectiveness of the proposed method in solving practical problems.
Developing of Bluetooth mesh flooding between source-destination linking of nodes in wireless sensor networks
Authors: Mohsin Shaymaa Kadhim , Mohammed Maysoon A. , Yassien Helaa Mohammed
Published: January 2022

Bluetooth uses 2.4 GHz in ISM (industrial, scientific, and medical) band, which it shares with other wireless operating system technologies like ZigBee and WLAN. The Bluetooth core design comprises a low-energy version of a low-rate wireless personal area network and supports point-to-point or point-to-multipoint connections. The aim of the study is to develop a Bluetooth mesh flooding and to estimate packet delivery ratio in wireless sensor networks to model asynchronous transmissions including a visual representation of a mesh network, node-related statistics, and a packet delivery ratio (PDR). This work provides a platform for Bluetooth networking by analyzing the flooding of the network layers and configuring the architecture of a multi-node Bluetooth mesh. Five simulation scenarios have been presented to evaluate the network flooding performance. These scenarios have been performed over an area of 200×200 meters including 81 randomly distributed nodes including different Relay/End node configurations and source-destination linking between nodes. The results indicate that the proposed approach can create a pathway between the source node and destination node within a mesh network of randomly distributed End and Relay nodes using MATLAB environment. The results include probability calculation of getting a linking between two nodes based on Monte Carlo method, which was 88.7428 %, while the Average-hop-count linking between these nodes was 8. Based on the conducted survey, this is the first study to examine and demonstrate Bluetooth mesh flooding and estimate packet delivery ratio in wireless sensor networks