bluuebunny/crossref_metadata_2025 huggingface dataset:
ADVANCES IN THE NEUROSURGICAL AND COMBINED TREATMENT OF PATIENTS WITH ACROMEGALY
Authors: Ibrahim Sameh R.A. , Shkarubo Alexey , Astafyeva Ludmila , Chmutin Gennady , Chmutin Egor
Published: October 2021

Aim. The study was carried out to identify and analyze the factors of a positive outcome of surgical and radiation treatment of acromegaly. Methods. The work was performed on clinical material and summarizes treatment results of 256 patients (90 males and 166 females). 86% of patients underwent surgical treatment, 14% of patients received radiation therapy during 2002–2018. Significance of factors of a positive outcome of treatment was carried out using the RStudio program. Results. The results of the study revealed that: 1. Significant factors (p <0.05) of a positive outcome of surgical treatment of acromegaly are somatostatin analogs (SSA) therapy before surgery, a small tumor size (microadenomas), and the absence of extrasellar tumor spread. 2. The most significant factor in achieving remission of acromegaly after non-radical adenomectomy is postoperative therapy with SSA (p <0.05). 3. Aggressive pituitary tumors invading surrounding structures, high baseline IGF-1 levels, unfavorable histological findings, macroadenomas, growth hormone levels above 10 μg/L before therapy, and extrasellar tumor spread were associated with less favorable outcomes of acromegaly radiation therapy (RT) (p <0.05). The most significant factor in achieving remission of acromegaly is SSA therapy after RT (p <0.05). Conclusion. Surgical treatment is the optimal primary treatment for acromegaly. Drug therapy with SSA is effective and the preferred treatment after non-radical surgery.
MORPHOMETRIC PATTERNS OF MAXILLAR Y APICAL BASE VARIABILITY IN PEOPLE WITH VARIOUS DENTAL ARCHES AT PHYSIOLOGICAL OCCLUSION
Authors: Kochkonyan Taisiya , Al-Harazi Ghamdan , Domenyuk Dmitry , Dmitrienko Sergey , Domenyuk Stanislav
Published: October 2021

Morphometric data on the structure of the craniofacial complex are reliable and diagnostically significant values that are of applied nature in terms of practical dentistry. Within this study, analysis of conebeam computed tomograms, biometric indicators of plaster models obtained from the jaws of 83 people (aged 21–35) with physiological occlusion and various types of dental, gnathic dental arches, the degree of proportion between the maxillary apical base and the inter-canine distance were identified. Depending on the dental arch type, the patients were divided into three groups. The morphometric study in the CBCT frontal plane was the distance between the canines tearing tubercles and the inter-canine distance in the apical area. The study outcomes revealed discrepancies between the calculated and actual indicators of the apical base width for all types of dental arches in people with physiological occlusion. In case of mesotrusive dental arches (incisional angle — 127–143°), the width of the apical base corresponded to the width of the dental arches between the canines, while the differences in indicators were not statistically significant. In people with retrusive dental arches (incisional angle exceeding 144°), the width of the dental arch was found to be significantly above the width of the apical bases. As far as protrusive dental arches are concerned (incisional angle below 126°), these patients featured predominance of the apical bases width over the inter-canine distance. The obtained data add to that already available in research literature regarding the relationships and dimensional features pertaining to the craniofacial complex structures, as well as have applied value in orthodontic clinical practice
A Digital Pressure Meter Equipped with Pressure Leak Detection
Authors: Erdyansyah Septian Nur Wahyu , Hamzah Torib , Titisari Dyah
Published: October 2021

A manual sphygmomanometer is an instrument used to measure blood pressure, and consists of an inflatable cuff, a mercury manometer (or aneroid gauge) and an inflation ball and gauge. To assess the condition, accuracy and safety of mercury and anaeroid sphygmomanometers in use in general practice and to pilot a scheme for sphyg- momanometer maintenance within the district. Therefore, it must be calibrated periodically. Using the MPX 5050GP sensor as a positive pressure sensor. Requires a maximum pressure of 300 mmHg. This tool is also equipped with a SD Card as external storage. The display used in this module is TFT Nextion 2.8”. After conductings measurements of the three comparisons consisting of Multifunction, DPM and mercury tensimeter to 6 times, the smallest result 0 mmHg and the largest results 251.52 mmHg. While the error in mercury tensimeter’s of leak test to module and rigel is 0.56% and 0.404%.
Infant Warmer Equipped with Digital Weight Scales
Authors: Al'Aziz Muhammad Jundi , Irianto Bambang Guruh , Kholiq Abd
Published: October 2021

Scales Scales in the world of health are used to measure human body weight such as baby scales. Newborns are very important to be weighed because it is used as a measure of the baby's health indication ranging from 2.4 kg to 4.2 kg. The author makes a tool for this to make it easier for users to weigh with a 7 segment display on the Infant Warmer tool and external calibration. By using a loadcell sensor with a maximum capacity of 5 kg, the loadcell can detect the weight of the load where the voltage generated by the loadcell of 0.7 mV at a load of 1 kg is amplified to 0.62 V by the PSA circuit using the AD620 IC and then processed by Arudino UNO as a microcontroller. The weight results will be displayed on the 7Segment display located on the Infant Warmer tool. In the study, the measured load included a weight of 0 kg to a maximum weight of 5 kg. The measurement of the data results was carried out 5 times each by comparing the modules that had been made with the standard weight, namely (lead). The data from the measurement results of the research module shows that when the weight of the measurement at 1 kg has an error percentage of 0.08%. Measurements at a weight of 2 kg have an error percentage of 0.05%. Measurement of weight 3 kg has a presentation error of 0.01%. Measurements at a weight of 4 kg have a presentation error of 0.02%. And measurements at a weight of 5 kg have an error percentage of 0.04%. Then the data from the measurement results of the research module shows the largest error presentation of 0.08% at a weight of 1 kg. And the data from the measurement results of the research module shows the smallest error presentation of 0.01% at a weight of 3 kg. Making a research module in the form of a scale placed on an infant warmer can make it easier for the wearer.
PHYSIOTHERAPY STUDENT'S MENTAL HEALTH AND COPING STRATEGIES USED WHILE PERFORMING COVID 19 DUTIES
Authors: Kaur Kang Jaspreet , J Vyas Neeta , Suthar Nidhi K
Published: October 2021

BACKGROUND: Coronavirus disease 2019 (COVID-19) –a global pandemic has severely affected humankind both
socially and psychologically. Due to shortage of manpower and excessive load the physiotherapy students were also
deputed for rendering their services in various departments ranging from screening to involvement in critical care. The study focuses on to
investigate the mental health of students while performing the duties and also the coping strategies used by them to overcome the negative effects
of the pressure of work.
METHOD: A Cross-sectional study was conducted by using an online, web-based questionnaire, which was distributed to physiotherapy
students who worked during the pandemic from April 2020 to June 2021. The respondents were recruited by the non-random convenience
sampling method.
RESULTS: A total of 448 responses were received in the survey and the majority (more than 40%) of students agreed that they were stressed and
anxious while performing their duties. Moreover, more than 75% students relieved the stress by self motivation and family support as a coping
strategy
CONCLUSION: This study indicated that physiotherapy students were experiencing psychological, emotional distress , and physical while
performing the COVID- 19 duties.
EVALUATION OF KNOWLEDGE, ATTITUDE AND PRACTICE OF INHALATION SEDATION IN CHILDREN AMONGST PEDODONTISTS AND GENERAL DENTAL PRACTITIONERS IN MANGALORE, INDIA
Authors: Bhardwaj Shrishty , Anand Apoorva , K David , Kathuria Abhinav
Published: October 2021

Inhalation sedation is a minimally depressed level of consciousness that retains the patient's ability to maintain an airway
independently and continuously and respond to stimulation and command. Found to be safe for use in dentistry with
positive outcomes, it is used to manage anxiety in pediatric patients during procedures. Aim of our study was to determine the frequency of usage
of inhalation sedation as adjunctive management technique in children by Dentists.
A Cross sectional study was conducted with pre-structured questionnaire given to Pedodontists and General dental practitioners in various Dental
colleges and clinics in and around Mangalore. Total sample size was 72. Data was collected and analyzed using SPSS version 17.0 with the Test of
Proportions. 32 out of 72 participants were trained in usage of Inhalation Sedation, out of which 14 used it regularly. Out of the 80.56% dentists
not using it, majority said that expensive equipment, increased cost of treatment and potential complications were the main reasons for not using
it. 59.72% of participants wanted to gain information, knowledge and undergo training in the usage of Inhalation Sedation.58.33% agreed to use
it in their future dental career.
70.83% believed that knowledge and training to use Inhalation Sedation is integral part of dental curriculum for undergraduates. This study
showed willingness of the dentists to provide Inhalation Sedation as a behavior management technique to their patients. The lack of training,
costly equipment, increased cost of treatment are the main barriers to providing such services to the patients.
PRACTICALAPPLICATION OF SIX SIGMA DMAIC METHODOLOGY IN EVALUATION OF PRE-ANALYTICAL QUALITY INDICATORS IN LABORATORY SETTINGS
Authors: Gahukar Shailesh , Gitika Gitika , Kumar Ashok
Published: October 2021

The Six Sigma is a global management methodology that empowers clinical laboratories by better understanding of the
quality in their laboratories and helps in improving quality and subsequently reducing laboratory costs. The objective of
this prospective study was to practically apply Six Sigma on pre-analytical quality indicators i.e. pre-analytical phase errors of “Total Testing
Process” in laboratory at PGIMER Satellite Centre, Sangrur (Punjab). In this study Six Sigma DMAIC ( Dene, Measure, Analyse,
Improvement and Control) methodology was applied on routine Outpatient Department (OPD) samples received in hematology and
biochemistry laboratory from May, 2020 to July, 2020 after institutional ethical committee permission. Pre-analytical phase errors were taken as
pre-analytical quality indicators and were broadly classied in to requisition form and sampling errors. Sigma values and frequencies were
calculated using Westgard formula present online at (www. westgard.com > six sigma calculators) for pre-analytical phase errors. After that
Improvement phase of DMAIC methodology was done by training of laboratory technicians or personell involved in pre-analytical phase by
audio-visual aids. Six Sigma values were calculated again after improvement phase. A total of 787 requisition forms and 1105 samples were
studied before improvement phase and 889 requisition forms and 1400 samples were studied after improvement phase. Before improvement
phase, overall requisition form errors were working at 2.9 sigma and sampling process was working at 3.1 sigma but after improvement phase,
requisition form errors were working at 3.3 sigma and sampling process was working at 3.5 sigma. Before and after improvement phase the
sample rejection rate in laboratory improved from 1.90% to 0.93% highlighting the benecial concept of six sigma in laboratory in pre-analytical
phase leading to increased clinicians and patients'satisfaction and prevents unusual delaying of reports.
RELATION OF ELEVATED SERUM LIPIDS AND LIPOPROTEIN (A) TO OXIDATIVE STRESS IN PSORIASIS.
Authors: Kundu Dipankar , Paul Aniket , Basu Satyaki
Published: October 2021

Background: Psoriasis is a chronic inammatory disease with multisystem involvement. Psoriasis is an immune
mediated skin disease characterized by hyperproliferation of keratinocytes9 which is initiated and maintained by
inammatory mediators.
Objective: To determine the serum lipid disturbances in psoriasis. To assess the signicance of lipoprotein (a) levels in psoriasis.
Materials And Methods: 30 Number of cases of patients suffering from Psoriasis in the age group of 15-75 was included in the study.30 age and
sex matched healthy volunteers served as controls.
Results: Signicant elevation in levels of fasting glucose, creatinine, total cholesterol.triglycrides, VLDL, LDL, Lipoprotein (a), and
Malondialdehyde (MDA) was observed in cases compared with controls.
Conclusions: It is important to measure serum lipid level particularly cholesterol, LDL and TG in psoriatic patients for early screening of
hyperlipidemia to evaluate risk to atherosclerosis and vascular obstructive disorders and its complications.
FORMULATION AND EVALUATION OF DARIFENACIN HYDROBROMIDE TRANSDERMAL PATCH
Authors: Reddy K Aparna , K Latha , Basha Shaik Naseeb , B Sushma , T Haritha , Muliki Ramu
Published: October 2021

The aim of present study is to formulate and characterize darifenacin hydrobromide transdermal patch and the effects of
non-ionic surfactants span 20 and tween 20 on drug permeation were studied. Transdermal patches were prepared by
solvent casting method using PVA, PVP, HPMC E5, HPMC E15 polymers. Propylene glycol and Glycerol were used as plasticizers and Span 20
and Tween 20 were used as permeation enhancers. The prepared patches were evaluated for physicochemical properties like drug content,
thickness, weight variation, folding endurance, moisture uptake, watervapour transmission studies. Physicochemical properties have shown
better. Drug release studies by in-vitro diffusion, ex-vivo permeation as well as skin irritation. Formulations DPAT2, DPLT3 showed better drug
release rate, ux and Q when compared to DPAS2, DPLS2. From the results it was concluded that darifenacin hydrobromide transdermal patch 24
(DPAT2) formulation would reduce the administration frequency, side effects and may avoid uctuations of drug level in the blood in comparison
to immediate release formulations which might enhance the patient compliance.
EMOTIONS AND EXPERIENCES OF THE COVID CARE NURSES: A DESCRIPTIVE STUDY WITH EXPLORATORY APPROACH
Authors: K Rose. , J Vidya. , Hemalatha Lazar Anjalin
Published: October 2021

Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered ribonucleic
acid coronavirus isolated and identied from patients with unexplained pneumonia. The World Health Organization
(WHO) declared the disease as a pandemic on March 11, 2020. Hence the investigator was interested to explore the emotions and experience of
the covid care nurses during covid 19 pandemic. This would identify to manage the factors causing the emotions and make better arrangements
for good experience among these nurses.
Materials and Methods: This descriptive study was done with 54 Covid care nurses available during the data collection period by using selfadministered questionnaire in Pondicherry Institute of Medical Sciences
Results: The nding highlights that most of the nurses(43%) were on frequent duties in the covid wards than covid intensive care unit. 70% were
not positive to Covid-19 and majority (80%) had covid vaccination. Many (69%) of their family/friends were not infected by Covid-19 and most
of them (72%) had not witnessed death of a covid patient. Majority (74%) of covid care nurses did not have emotion of fear but had anxiety (70%)
for can't eat/drink and can't use toilet. The results show that nearly half of the covid care nurses overcame fear (46%) and anxiety (45%) emotions
because of condence at work & support from coworkers (39%), family and friend's support (37%) and faith in God (24%). Majority of the
nurses were highly exhausted in personal experience areas like interpersonal (86%), mental (82%), emotional (80%) and physical (72%)
whereas rarely exhausted (67%) in sleep experience. Nurses experienced highly adequate in work related aspects like team members number
(83%), resources (78%), time for care (100%), help from others(96%) whereas 100% covid care nurses experienced rarely adequate cooperation
from patient/relative.
Conclusion: This shows the signicance of the good working environment with supportive team, resources and time
Identiﬁcation of pathogen bacteria from camel (Camelus dromedarius) mastitis and investigation of antibiotic susceptibility
Authors: Kirkan Sükrü , Parin U ̆gur , Çapakçioglu Halil
Published: October 2021

The scope of this study was to investigate the presence of pathogenic bacteria in milk from female camels with mastitis and to select antibiotics for treatment with antibiotic susceptibility testing. A total of 40 milk samples taken from 20 dromedarian females, after application of CMT test and determination of SCC values, the camels were diagnosed with subclinical mastitis. Milk samples were inoculated into blood agar for identiﬁcation of bacterial agents leading to mastitis. A total of 4 (12.5%) Staphylococcus aureus, 4 (12.5%) S. auricularis, 2 (6.25%) S. pettenkoperi, 2 (6.25%) S. cohnii spp. cohnii, 2 (6.25%) S. equorum, 2 (6.25%) S. capitis, 2 (6.25%) Streptococcus agalactiae, 2 (6.25%) S. dysgalactiae, 4 (12.5%) Escherichia coli, 2 (%) 6.25) Pseudomonas pseudalcaligenes, 2 (6.25%) Corynebacterium pseudotuberculosis, 2 (6.25%) Aerococcus viridans and 2 (6.25%) Gemella morbillorum were identiﬁed. Gram-positive bacteria were sensitive to Levoﬂoxacin, Linezolid and Tetracycline and Daptomycin, resistant to Beta lactam-group antibiotics and macrolides. Vancomycin resistance was determined in S. aureus and S. cohnii spp. cohnii strains. Gram-negative strains are found generally susceptible to Cefepime and Pipersilin; resistant to Trimethoprim-sulfomethoxazole and Amoxicillin-Clavulanic acid. As a result, it is recommended to use antibiotic use to prevent the development of antimicrobial resistance as well as mastitis control methods such as the prevention of infection and monitoring the health status of the mammary of camels.
Aplikasi Layanan Administrasi Mahasiswa Jurusan dalam Membangun Tata Kelola Perguruan Tinggi (Studi Kasus: Jurusan Manajemen Informatika Politeknik Negeri Sriwijaya)
Authors: Isa Indra Griha Tofik , Ariyanti Indri
Published: October 2021

Layanan menjadi faktor utama dalam mengukur kualitas tata kelola di perguruan tinggi, saat ini layanan selalu terintegrasi dengan sistem informasi. Politeknik Negeri Sriwijaya (Polsri) saat ini sudah mengimplementasikan layanan berbasis sistem informasi, namun yang menjadi tantangan dalam pengembangan sistem di Polsri yaitu bagaimana mengakomodir kebutuhan sistem informasi hingga menyasar di level Jurusan dan Program Studi, layanan tersebut bersifat rutin, administratif dan berkaitan langsung dengan mahasiswa. Jurusan Manajemen Informatika (MI) merupakan salah satu jurusan yang memiliki jumlah mahasiswa yang banyak sehingga diperlukan penerapan sistem informasi dalam layanan administrasi mahasiswa. Saat ini sistem layanan yang berjalan di MI masih terpusat pada sistem informasi akademik yang cakupannya meliputi pengeloaan jadwal, penilaian mahasiswa, dan administrasi pengajaran dosen. Namun untuk layanan administrasi mahasiswa belum mengimplementasikan sistem yang terkomputerisasi. Berdasarkan observasi lapangan dan wawancara dengan pengadministrasi jurusan, layanan administrasi yang memerlukan implementasi sistem informasi antara lain: (1) layanan informasi akumulasi kompensasi mahasiswa, (2) layanan pendataan beasiswa, (3) layanan permohonan pelaksanaan Kerja Praktek/ Laporan Akhir/ Tugas Akhir, (4) layanan permohonan Stop Out dan (5) Umpan balik kualitas layanan dari mahasiswa. Hasil akhir dari penelitian ini berupa aplikasi layanan administrasi mahasiswa berbasis web yang mengakomodir layanan mahasiswa dari kelima aspek tersebut
Sistem Informasi Pengolahan Data Nilai Siswa Berbasis Web (Studi Kasus Mi Darussalam Tlogoboyo)
Authors: Afifudin Muhammad , Riyantomo Agung
Published: October 2021

Pengolahan nilai di Madrasah Ibtidaiyah (MI) Darussalam Tlogoboyo masih menggunakan Aplikasi Spreadsheet dalam pengolahan data nilainya. Entri data nilai dilakukan dengan cara menyalin atau menggandakan file data siswa, sehingga menimbulkan terjadinya penumpukan data yang berdampak pada sulitnya mendapatkan informasi data nilai yang terpadu karena harus membuka file datanya satu persatu. Antar data satu dengan yang lain belum berelasi, sehingga banyak terjadi duplikasi data yang menyebabkan banyak file yang dibuat. Dari kasus tersebut mendorong penulis untuk melakukan penelitian dengan membuat sistem informasi pengolahan data nilai siswa. Pada proses pembuatan sistem penulis menggunakan metode Waterfall sebagai metode pengembangan perangkat lunak. Metode tersebut meliputi tahap Requirement, Desain, Implementation, Verification, dan Maintenance. Framework PHP yang digunakan yaitu Code Igniter didukung dengan database MySQL untuk mengolah basis datanya. Hasilnya yaitu sistem informasi pengolahan data nilai siswa berbabasis web (studi kasus MI Darussalam) ini merupakan sistem yang memberikan informasi kepada guru ketika ingin melakukan penginputan data nilai hasil kegiatan belajar dan siswa dapat secara langsung melihat nilai rapor hasil kegiatan belajar. Informasi yang disajikan pada sistem ini meliputi informasi guru dapat secara langsung menginputkan nilai hasil kegiatan belajar mengajar yang berupa rapor sehingga siswa dapat langsung melihat rapor hasil belajar mengajar dengan  secara langsung.
Sistem Penyewaan Mobil Berbasis Web (Studi Kasus Sastro Rent Car)
Authors: Mufidah Nurul Lubna , Mauluddin M Subchan
Published: October 2021

Rental mobil merupakan salah satu usaha yang bergerak dibidang jasa yang dapat membantu masyarakat ketika memerlukan jasa persewaan mobil atau kendaraan dalam berbagai keperluan pribadi dan keperluan perusahaan. Ditinjau dari permasalahan yang terjadi yaitu tentang bagaimana cara calon customer agar lebih mudah untuk meminjam mobil tanpa harus ke lokasi penyewaan mobil langsung, maka penulis disini merancang dan mengimplementasikan sebuah sistem informasi penyewaan mobil berbasis website. Dengan website ini penyewa dapat menyewa mobil sesuai dengan keinginannya dengan mudah tanpa harus bertemu langsung ke tempat penyewaan mobil terlebih dahulu. Sistem ini dibuat menggunakan metode waterfall dengan PHP dan didukung oleh database MySQl untuk mengolah basis datanya. Hasil dari penelitian ini yaitu sebuah sistem informasi penyewaan mobil berbasis website (studi kasus Sastro Rent Car). Website ini merupakan website rental mobil yang menyewakan beberapa jenis mobil dan menyediakan jasa sopir. Pembuatan website ini menampilkan informasi tentang spesifikasi mobil yang akan disewakan terdiri dari harga sewa mobil, spesifikasi mobil dan merk mobil.
Sistem Informasi E-Commerce Furniture Berbasis Web pada Toko Mebel Ubaidillah Kamal Jepara
Authors: Achyar Muchammad Tirozul , Pratama Fandy Indra
Published: October 2021

Pesatnya perkembangan teknologi internet tidak ada batasan lagi orang untuk membantu atau mengambil informasi dengan cepat. Teknologi informasi akan mendominasi seluruh kegiatan yang ada karena pengguna internet menjurus kepada cyberspace yang memberikan kemajuan di segala bidang terutama pada bidang e-commerce yang menyababkan sistem penjualan dari konvensional menjadi digital. Toko Mebel Ubaidillah Kamal Jepara merupakan sebuah usaha yang bergerak di bidang furniture. Sistem penjualan dan promosi masih menggunakan sistem konvensional. Dari kendala tersebut membutuhkan sebuah sistem informasi penjualan untuk mengelola.. Dalam penelitian ini menggunakan Metode Waterfall dan Penelitian yang dilakukan menghasilkan sistem informasi e-commerce furniture berbasis web pada toko mebel Ubaidillah Kamal Jepara untuk memudahkan pembeli dalam melakukan pemesanan.
Characteristics of Farmers in Suboptimal Land Agroecosystems and the Implications of the Application of Farm Technology
Authors: Suharyon Suharyon , B Saidi Busyra
Published: October 2021

The area of West Tanjung Jabung District is dominated by tidal land agroecosystems so that the farming pattern that develops is based on tidal land. This research aimed to study the characteristics of farmers in tidal land agroecosystems and their implications for the application of farming technology. The research was conducted in Bunga Tanjung Village, Betara Subdistrict, West Tanjung Jabung District in 2019, involving 40 farmers who were randomly selected as respondents. The descriptive data analysis showed the first, farming on tidal land was characterized by the control of relatively unprocessed and cultivated farm land, low crop intensity of food commodities, and low levels of productivity resulting in unfulfillable farming results properly. The second, the biophysical conditions of farming land wereless conducive to influence the decisions of farmers to Apply farming technology. The third, the opportunity to increase farming productivity in tidal lands was still wide open by optimizing the potential utilization of farmland resources based on the strengths and weaknesses of farmers. The fourth, the strategies to increase productivity in tidal land agroecosystem areas were conducted by diversifying into multi- enterprises, implementing integration patterns between commodities, accelerating technology dissemination, and encouraging the growth of partnership networks. In order for these strategies to be implemented, it is necessary to have a soft credit scheme policy which in its implementation it is followed by assistance of extension agents and researchers.
The Main Disease and its Attacks in the Generative Phase of Maize (Zea Mays L) in the Freshwater Swamps of South Sumatra
Authors: Hamidson Harman , Efendi Riski Anwar
Published: October 2021

In South Sumatra, the ​​freshwater swamps is 157,846 hectares, with this wide freshwater swamps, it can be used for crops food  cultivation, one of which is maize. The purpose of this study was to provide information on the identification and attack of maize disease in freshwater swamps of South Sumatra. The research method was purposive sampling. The results of the study identification that the symptoms of maize leaf rust attack, seen from the physiology of maize leaves, were the lumps or pustules of orange color such as rust and the symptoms of maize leaf blight seen from the physiology of maize leaves, were small oval brownish lines like burning leaves. The leaf rust disease had an attack rate of 90% and the maize leaf blight reached 98%. Based on the results of this study, the main disease of maize attacking in the generative phase was the leaf rust (Puccinia polysora) and maize leaf blight (Bipolaris maydis).
A COMPARATIVE PHARMACEUTICO ANALYTICAL STUDY OF YASTIMADHU KSHEERAPAKOTTHA GHRITHA AND YASTIMADHU GHRITHA
Authors: Dr.Ramakiran  , Dr.Harshitha M
Published: October 2021

Drug research is an important part of pharmaceutical field especially in Ayurveda pharmaceutics to revalidate and establish various formulations. Ghritha kalpana has got prime importance due to a special property of Ghritha i.e Samskarasyanuvartana. Ksheera ghritha and Ghritha are explained with different properties in Ayurveda classics. Present study is to compare between Yastimadhu Ksheera ghritha and classical Yastimadhu ghritha by organoleptic and analytical parameters. Ksheera ghritha procedure may bypass the long procedure , maximise the percentage of extract in Ghritha. Reference of Ksheera ghritha is
available in various classical texts like Sushruta samhitha1 etc. Ksheera ghritha said to have properties like Netrya , Sangrahi , Rakthapitta hara etc.
Ksheera ghritha of Yastimadhu prepared by preparing Ksheerapaka taken as G1 and Yastimadhu Ghritha prepared by normal classical way taken as G2. Analytical study for standardization of both samples were carried out on the basis of classically illustrated organoleptic tests and modern parameters of physico-chemical properties like LOD, Refractive index , Saponification value etc., and TLC done for qualitative analysis. By this study the major difference between Ksheera ghritha and Ghritha are established giving further scope for clinical research to establish efficacy of same.
KEY WORDS : Ayurveda, Ghritha, Yastimadhu, Ksheerapaka.
Pathogenesis of COVID-19: ACE2, Cytokine Storm and Extrapulmonary Manifestations
Authors: Naeem Muhammad , Muhaymin Abdul Muhaymin , Abbasi Hyder Wajid , Ullah Naeem , Haider Adnan , Jamal Syed Babar , Subhan Fazli
Published: October 2021

The coronavirus disease 19 (COVID-19) is a global pandemic of the twenty-first century and currently fourthwave is creating fear and panic worldwide. It is caused by severe acute respiratory syndrome coronavirus 2(SARS-COV-2), a highly contagious viral infection of humans. The COVID-19 can be spread mainly throughrespiratory droplet particles and in contact with a COVID-19 infected person. Clinical manifestation of COVID-19patients includes cough, fever, diarrhea, loss of taste and smell. In critical cases of COVID-19, the developmentof pneumonia and dyspnea leads to acute respiratory distress syndrome that may cause the death of thepatient. It is well established that Angiotensin-Converting Enzyme 2 (ACE2) receptors on alveolar cells act as anentry gate for the SARS-COV-2. However, ACE2 is also highly expressed in multiple extrapulmonary vital organssuch as the gastrointestinal system, cardiovascular system, kidney, etc. Therefore, the direct viral entry in theseorgans can be a likely pathway of injury. In addition, decoupling of immune responses leads to the cytokinesstorm, which might contribute to the injury of extrapulmonary organs. In this review, we report the multipleorgan pathogenesis and clinical manifestations of COVID-19 patients, which could aid clinicians and researchersin prioritizing therapeutics remedies and developing research for all vital body systems involved.
First Follow up Response Evaluation of Conventional vs Drug Eluting Bead Transarterial Chemo Embolization: A Comparative Study at Tertiary Care Radiology Centre, Rawalpindi
Authors: Fayyaz Afshan , Sheraz Atif , Rahim Hyder Raza , Abbas Ghulam
Published: October 2021

Objective: To compare treatment with drug eluting beads Transarterial Chemoembolization (DEB TACE) vsConventional Transarterial chemoembolization (cTACE) in hepatocellular carcinoma (HCC) patients at firstfollow up.Study Design: Comparative Interventional Study.Place and Duration of Study: The study was conducted in the department of Radiology CMH Rawalpindiand Armed Forces Institute of Radiology and Imaging (AFIRI), Rawalpindi from July 2015 to May 2019.Materials and Methods: 254 patients were included in the study. Conventional TACE was done on 176 patientsand DEB TACE was done on 78 patients. All patients were called for follow up after 06 weeks. First responseevaluation of treated lesions in these patients was seen on triphasic CT liver after 06 weeks of TACE therapy.Results: On first follow up, out of 176 patients with cTACE, 'Total response' was seen in 90(51.1%) patients,'Partial response' in 76 patients (43.1%),'No response' in 04(2.27%) patients.' Progressive disease' was seen in06(3.4%) patients.DEB TACE was done in 78 patients. Out of these, 27 (34.6%) patients showed 'Total response'. 50(64.1%)patients showed 'Partial response', 'Progressive disease' was seen in one patient (.02%).Conclusion: The findings of this study have shown that c TACE has a better outcome regarding first responseevaluation. 'No response' to treatment was not seen in any patient with DEB TACE.
Used Aromatic Medicinal Plants in three Human Agglomerations of Zaaer (Morocco): Used Species, Used Parts of the Plant and the Ways of Use
Authors: Khal Layoun Soad  , Ibrahimi Halima  , Benkhnigue Oufae  , Lerhlibi Hajar  , Bour Abdellatif  , Mohamed Fadli
Published: October 2021

In this work, using a questionnaire survey, we have developed an inventory of the used aromatic medicinalplants in traditional medicine by the population of the main human settlements on the «Zaaer» plateau, theused parts of the plant and the use way of these parts. So, 52 species arranged in 24 botanic families and 22orders were inventoried. The most represented systematic groups in species (4 to 7) belong to the Order ofApiales, Family Apiaceae and the Order Lamiales represented by the Family of Lamiaceae; The Order ofAsterales represented by the Family of Asteraceae and the Order of Capparales represented by the Family ofBrassicaceae. The remaining botanical families and Orders have only one or two species each. The infusionand the decoction remain the most frequent modes of use and it is the aerial part of the plant which isthe most used. The treated diseases are very diverse: 46% of the species are used for the treatment of thedigestive tract, 25% for diabetes, 21% for cosmetic 20% for cardiovascular problems, 20% for microbialinfections and intoxications, 13% for prostate and urinary diseases. The treatment of respiratory diseasesconcerns only 7% of the used spécies.
SOME ISSUES OF GRANTING A SUSPENDED SENTENCE
Authors: Адылин Дмитрий Михайлович
Published: October 2021

В настоящее время одним из приоритетных направлений развития государства является улучшение демографической ситуации в стране, а также поддержка материнства, детства и семьи. Для реализации указанных целей российская правовая политика предусматривает различные механизмы, одним из которых является предоставление отсрочки отбывания наказания беременным женщинам, женщинам и мужчинам, являющимися единственным родителем, до достижения ребенком четырнадцатилетнего возраста. Социальное назначение данного вида отсрочки заключается в обеспечении прав детей на развитие и воспитание в родной семье. В последнее время набирает популярность суррогатное материнство, которое предусматривает вынашивание и рождение женщиной ребенка для другого лица или лиц, которые станут родителями ребенка после его рождения. При этом в российском законодательстве остаются неурегулированными некоторые вопросы, связанные с реализацией требований отсрочки отбывания наказания суррогатным матерям. В статье рассмотрены проблемы правовых последствий для суррогатных матерей, которым предоставлена отсрочка отбывания наказания, в случае передачи ребенка в соответствии с требованиями договора потенциальным родителям и предложены пути их решения.

Currently, one of the priorities of the state's development is to improve the demographic situation in the country, as well as support for motherhood, childhood and family. In order to achieve these goals, the Russian legal policy provides for various mechanisms, one of which is the provision of deferred sentence for pregnant women, women and men who are the only parent, until the child reaches the age of fourteen. The social purpose of this type of deferral is to ensure the rights of children to development and upbringing in their native family. Surrogacy, which involves the carrying and giving birth of a child by a woman for another person or persons who will become parents of the child after its birth, has recently gained popularity. At the same time, some issues related to the implementation of the requirements for postponing the serving of sentences for surrogate mothers remain unresolved in Russian legislation. In particular, this article discusses the problems of legal consequences for surrogate mothers who are granted a suspended sentence in the case of the transfer of the child in accordance with the requirements of the contract to potential parents and suggests ways to solve them.
PROBLEMS OF INVESTIGATING MURDERS COMMITTED IN INSTITUTIONS THAT PROVIDE ISOLATION FROM SOCIETY
Authors: Кубанов Валерий Викторович , Кузьмина Дарья Владимировна
Published: October 2021

В статье анализируются вопросы организации расследования убийств, совершаемых в условиях учреждений, обеспечивающих изоляцию от общества. Рассмотрены элементы криминалистической характеристики данных преступлений. Изучены и проанализированы наиболее распространенные способы совершения пенитенциарных убийств, типичные следы и обстановка преступного события. Особое внимание уделено вопросам исследования психологического портрета личности пенитенциарного преступника. Сделан вывод о том, что тактические особенности расследования убийств в местах лишения свободы в значительной степени обусловлены спецификой исправительного учреждения. Исследованы правовые и организационные аспекты привлечения специалистов к участию в следственных действиях, вопросы организации деятельности судебно-медицинского эксперта. Указано на особое значение неотложности проведения осмотра места происшествия в условиях учреждения уголовно-исполнительной системы. Предложено производство осмотра силами данного учреждения, что позволит предотвратить возможную утрату доказательственной информации. Дана оценка использованию свидетельских показаний осужденных в судебном разбирательстве в качестве доказательств по делам о пенитенциарных убийствах. На основе обобщения опыта работы органов и учреждений ФСИН России выделены основные направления деятельности, в наибольшей степени влияющие на расследование убийств, совершенных осужденными и лицами, содержащимися под стражей.

The article analyzes the issues of organizing the investigation of murders committed in institutions that provide isolation from society. The elements of the criminalistic characteristics of these crimes are considered. The most common methods of committing penitentiary murders, typical traces and the situation of a criminal event are studied and analyzed. Special attention is paid to the study of the psychological portrait of the personality of the penitentiary criminal. It is concluded that the tactical features of the investigation of murders in places of deprivation of liberty are largely determined by the specifics of the correctional institution. The legal and organizational aspects of attracting specialists to participate in investigative actions, issues of organizing the activities of a forensic medical expert are investigated. The special importance of the urgency of conducting an inspection of the scene of the incident in the conditions of the institution of the penitentiary system is indicated. It is proposed to conduct an inspection by the forces of this institution, which will prevent the possible loss of evidentiary information. The article evaluates the use of the testimony of convicted persons in court proceedings as evidence in cases of penitentiary murders. Based on the generalization of the experience of the bodies and institutions of the Federal Penitentiary Service, the main areas of activity that most affect the investigation of murders committed by convicts and persons in custody are identified.
PROSPECTS FOR THE DEVELOPMENT AND APPLICATION OF CERTAIN NON-CUSTODIAL PUNISHMENTS
Authors: Мусалева Анна Владимировна , Гараев Олег Анатольевич
Published: October 2021

В статье проведен общетеоретический анализ категории наказаний, не связанных с лишением свободы. Выявлены место и роль не связанных с лишением свободы наказаний в системе уголовных наказаний, применяемых в России. Выделены основные виды этих наказаний и приведены их отдельные характеристики. Системный анализ действующего законодательства позволил выделить виды наказаний, которые по соответствующим критериям могут быть причислены к таким, что не реализуются путем лишения лица свободы: штраф, ограничение свободы, исправительные работы, обязательные работы и др. Установлено, что перспективы для расширения подобных видов наказаний открыты, но механизмы их воплощения в практической деятельности нуждаются в обновлении для повышения эффективности уголовной политики. Авторами выявляются и характеризуются особенности назначения наказаний, не связанных с лишением свободы лица, в отношении которого вынесен приговор. Кроме того, авторами отмечаются основные проблемы назначения отдельных видов наказаний этой группы в современной правоприменительной практике. Подчеркивается необходимость дальнейшей научной разработки проблематики вопроса и внесения изменений и дополнений в законодательство в целях его совершенствования.

The article provides a general theoretical analysis of the category of non-custodial punishments. The place and role of non-custodial punishments in the system of criminal punishments used in Russia has been revealed. The main types of these punishments are highlighted and their individual characteristics are given. A systematic analysis of the current legislation made it possible to identify the types of punishments that, according to the relevant criteria, can be ranked among those that are not implemented by imprisoning a person: a fine, restriction of liberty, corrective labor, compulsory labor, etc., but the mechanisms of their implementation in practice need to be updated to increase the effectiveness of criminal policy. The authors identify and characterize the specifics of sentencing that are not related to the deprivation of freedom for the person who is sentenced. In addition, the authors point out the main problems of assigning certain types of punishments to this group in modern law enforcement practice. The need for further scientific development of the problematics and the introduction of amendments and additions to the legislation in order to improve it is emphasized.
Pengaruh Konsentrasi Resin dan Suhu Pemanas Awetan pada Penyempurnaan Lipatan Permanen Kain Poliester 100%
Authors: Herawati Feny Nur
Published: October 2021

Permanent press by using resin will increase the resistance of the desired material properties. The refinement process to obtain permanent fold properties in polyester fibers is obtained by forming a polymer resin layer on the surface of the fabric. The more resin used, the less the ability of the fabric to come back from the crease, so the permanent crease finish will be more permanent.

However, with more and more resin polymerizing on the surface, the fabric will be stiffer and can reduce the tensile strength of the fiber, the occurrence of the resin polymerization process is influenced by the temperature of the preserved heating when the temperature is less then the resin is not formed perfectly or if the temperature is too high it can cause damage to the fiber. This test was carried out on 100% polyester fabric with variations in the concentration of melamine formaldehyde resin 40 g/l, 50 g/l, 60 g/l, 70 g/l and variations in the curing temperature of 1600C, 1700C, 1800C, 1900C. Tests carried out include re-testing of the folds and tensile strength of the fabric. The results showed that the optimum conditions achieved in this experiment were at a concentration of melamine formaldehyde resin of 60 g/l with a preserved heating temperature of 1700C, a low folding angle value of 740 was obtained with a tensile strength value that above the minimal standards, namely the warp 75.7 Kg and weft 22.7 Kg.
Pengaruh Variasi Timing Opening Angle Terhadap Jumlah Weft Stop pada Pertenunan Kain dengan Anyaman Keper 2/1 1 di Mesin Air Jet Loom
Authors: Pravitasari Filly , Kusumadewi Afriani
Published: October 2021

In the weaving process, the process of launching the weft yarn is an important thing to consider. One of the obstacles that often occurs in the process of launching feed using a water jet loom machine is the amount of feed stuck (weft stop). The cause of the weft stop is because the process of opening the warp mouth is not clean and the weft thread slides inappropriately or too fast so that the warp mouth is in a small condition. Variations in timing opening angle of 700, 800 and 900 determine the size of the warp mouth opening, the time the weft will slide and the time the weft will arrive. From the three variations of the timing opening angle, the number of weft stops at the timing opening angle of 800 is smaller than the timing opening angle of 700 and 900, which is namely the number of big loops 0.6 times and end loops 0.8 times per hour.
Optimasi Persediaan Bahan Baku Deker melalui Metode Material Requirement Planning pada CV Ajax Sport
Authors: Bhagya Tombak Gapura , Komala Elly
Published: October 2021

Inventory of raw materials is the initial process in planning and controlling production. Because by planning and controlling raw materials, it becomes one of the processes to produce an optimal production system. In order for raw material inventory to be controlled, the MRP method is used in its completion. In the case study at CV Ajax Sport, it is known that controlling raw material inventory using MRP produces an inventory value of Rp. 139,911,944,- for 12 weeks, with the number of orders for F300 raw materials as many as 71,716 units and for G300 raw materials as many as 67,297 units. And this value shows a very large value both financially and product units, so it must be managed appropriately and accurately.
PENGARUH PROMOSI DAN HARGA TERHADAP KEPUTUSAN PEMBELIAN PRODUK KOPI KOPLAKAN
Authors: Zainullah Vernanda Choirul
Published: October 2021

Perkembangan makanan dan minuman di Indonesia mengalami pertumbuhan yang semakin berkembang pesat dari tahun ke tahun. Industri makanan dan minuman memiliki pangsa pasar yang besar di Indonesia. Kopi Koplakan adalah perusahaan yang bergerak di bidang minuman dengan produknya kopi ijo yang bernama Kopi Koplakan. Omzet penjualan dari Kopi Koplakan terus menurun dan hanya pernah mencapai target pada bulan April dan Mei dalam perioede Januari sampai Agustus 2019. Pihak Kopi Koplakan memutuskan untuk membuat pra survey yang bertujuan untuk mengetahui permasalahan yang ada di Kopi Koplakan. Setelah dilakukannya pra survey, diketahui bahwa promosi dan harga menjadi masalah dari Kopi Koplakan. Oleh karena itu peneliti ingin meneliti pengaruh promosi dan harga terhadap keputusan pembelian dari produk Kopi Koplakan. Penelitian ini dilakukan untuk mengetahui apakah ada pengaruh promosi dan harga terhadap keputusan pembelian produk Kopi Koplakan. Variabel yang digunakan dalam penelitian ini adalah promosi dan harga sebagai variabel bebas, dan keputusan pembelian sebagai variabel terikat. Penelitian ini menggunakan metode kuantitatif dan analisis linier berganda sebagai model analisisnya. Sampel dari penelitian ini berjumlah 140 orang responden dan diolah dengan menggunakan SPSS 23. Hasil dari penelitian ini menyatakan bahwa promosi dan harga memiliki pengaruh yang positif dan signifikan terhadap keputusan pembelian produk Kopi Koplakan.
Kata kunci: Promosi, Harga, dan Keputusan Pembelian
PENGARUH PERCEIVED RISK, TRUST, DAN FASHION INNOVATIVENESS TERHADAP ONLINE PURCHASE INTENTION INCENDIO
Authors: Estella Nadine
Published: October 2021

Minat beli online semakin meningkat beriringan dengan meningkatnya pengguna internet di Indonesia. Membeli produk secara online tidak lepas dari risiko yang dirasakan konsumen sebelum membeli. Tak hanya risiko, kepercayaan juga menjadi faktor kuat penentu yang menjadi pertimbangan konsumen saat hendak membeli produk secara online. Produk fashion merupakan salah satu produk yang diminati di online. Salah satunya adalah produk kaos yang merupakan kebutuhan sehari-hari konsumen. Banyaknya produk fashion yang dijual secara online, mengakibatkan munculnya brand-brand fashion baru sehingga persaingan menjual produk fashion secara online menjadi semakin ketat. Oleh karena itu adanya faktor inovasi fashion konsumen menjadi potensi dimana para inovator fashion akan membeli produk fashion secara online yang mengikuti tren terkini. Tujuan dari penelitian ini adalah untuk mengetahui dan menganalisis pengaruh persepsi risiko, kepercayaan, dan innovator fashion terhadap minat pembelian online produk fashion Incendio. Penelitian ini merupakan penelitian kuantitatif dengan metode pengumpulan data menggunakan kuesioner yang dibagikan kepada Mahasiswa Universitas Ciputra jurusan International Business Management sebanyak 140 orang. Variabel dalam penelitian ini yaitu: Persepsi Risiko (X1), Kepercayaan (X2), Inovator Fashion (X3) dan Minat pembelian online (Y). Hasil dari penelitian ini menunjukan persepsi risiko, kepercayaan, dan innovator fashion berpengaruh signifikan terhadap minat pembelian online.
Kata Kunci: Persepsi risiko, Kepercayaan, Inovasi Fashion