bluuebunny/crossref_metadata_2025 huggingface dataset:
Prediction of Poly-Crystalline PV Performance by Machine Learning and Analytical Modeling in Jordan
Authors: Faouri Sinan S. , Abdallah Salah , Salameh Dana Helmi
Published: August 2023

In this work, different prediction models of poly-crystalline PV
performance in Jordan are studied based on experimental results,
analytical, and machine learning models. Two types of PV grid connected
systems working at Applied Science Private University in Amman-Jordan,
having a power capacity of 5 KWp each were involved in study. These two
PV systems are fixed with tilt angle of 11 which
are: poly-crystalline south directed, and poly-crystalline EW directed
(which means that half of these PV modules directed to the east and the
other half is directed to the west). Both PV systems have been trained
via linear regression, LASSO, ElasticNet in addition to ANN algorithms.
Linear regression model surpasses all the other three models when
compared by different performance measures. The results for
poly-crystalline EW directed PV system show that the yearly analytical
electrical power generation is 1433.9 KWh/KWp, where the value of error
equals 3.12% as compared with experimental value. Whereas the yearly
electrical power generation by prediction using linear regression is
1510.45 KWh/KWp, where the value of error equals 2.1% as compared with
experimental value. In the case of poly-crystalline south directed PV
system, the yearly analytical electrical power generation is 1772.9
KWh/KWp, where the value of error equals 7.89% as compared with
experimental value. Whereas the yearly electrical power generation by
prediction using linear regression is 1658.15 KWh/KWp, where the value
of error equals 1.5%. Also, the results show that the productivity of
poly-crystalline south directed PV system is better than the
poly-crystalline EW directed system with power gain equals 23.64% using
analytical method, equals 10.43% using experimental method, and equals
9.77% using prediction by linear regression.
Age at Type 2 Diabetes Diagnosis and Cause-Specific Mortality: Observational Study of Primary Care Patients in England
Authors: Barker Mary M. , Davies Melanie J. , Sargeant Jack A. , Chan Juliana C.N. , Gregg Edward W. , Shabnam Sharmin , Khunti Kamlesh , Zaccardi Francesco
Published: August 2023

OBJECTIVE

To examine the associations between age at type 2 diabetes diagnosis and the relative and absolute risk of all-cause and cause-specific mortality in England.

RESEARCH DESIGN AND METHODS

In this cohort study using primary care data from the Clinical Practice Research Datalink, we identified 108,061 individuals with newly diagnosed type 2 diabetes (16–50 years of age), matched to 829,946 individuals without type 2 diabetes. We estimated all-cause and cause-specific mortality (cancer, cardiorenal, other [noncancer or cardiorenal]) by age at diagnosis, using competing-risk survival analyses adjusted for key confounders.

RESULTS

Comparing individuals with versus without type 2 diabetes, the relative risk of death decreased with an older age at diagnosis: the hazard ratio for all-cause mortality was 4.32 (95% CI 3.35–5.58) in individuals diagnosed at ages 16–27 years compared with 1.53 (95% CI 1.46–1.60) at ages 48–50 years. Smaller relative risks by increasing age at diagnosis were also observed for cancer, cardiorenal, and noncancer or cardiorenal death. Irrespective of age at diagnosis, the 10-year absolute risk of all-cause and cause-specific mortality were higher in individuals with type 2 diabetes; yet, the absolute differences were small.

CONCLUSIONS

Although the relative risk of death in individuals with versus without type 2 was higher at younger ages, the 10-year absolute risk of all investigated causes of death was small and similar in the two groups. Further multidecade studies could help estimate the long-term risk of complications and death in individuals with early-onset type 2 diabetes.
Güneş Enerjili Eko Tasarım Kereste Kurutma Sistemi
Authors: Sarı Emre , Güven Yaren , Aktaş Mustafa
Published: August 2023

Sera gazı emisyonlarının giderek artması küresel ısınma ve iklim sorunlarının ortaya çıkmasına neden olmaktadır. İklim değişikliği ve küresel ısınma sorunlarının önüne geçilmesi için emisyonların ve fosil yakıtların kullanımının azaltılması gerekmektedir. Paris İklim Anlaşması kapsamında karbon emisyon değerlerinin azaltılması, kendi enerjisini üreten, yenilenebilir ve çevre kirliliğinin en az olduğu sistemlere yönelim hedeflenmektedir. Bu çalışmada, kerestenin güneş enerjisi ile farklı koşullarda sürdürülebilir bir sistem ile kurutulmasına yönelik yeni bir eko tasarım yapılması amaçlanmıştır. Kurutma kusurları, kurutulmuş kereste kalitesini önemli ölçüde etkilemektedir. Yeni bir hava akış yapısına sahip tasarım ile güneş enerjisiyle hem sıcak hava hem de elektrik üretimi hedeflenmiştir. Kendi enerjisini üreten yeni tip enerji depolamalı ve enerjinin etkin kullanıldığı eko tasarım kapalı çevrim sıcaklık ve bağıl nem kontrollü bir kurutma sistemi tasarlanmıştır. Ortaya konulan sistem ile enerji verimliliğinin artırılması, karbon emisyon değeri ve çevre kirliliğinin azaltılması amaçlanmıştır. 3,03 kWh/kg su özgül enerji tüketim değeri kabulü ile bu tasarımda üründen 1 ton nem alındığında 1,33 ton CO2-eşdeğer sera gazı emisyonu salımı önlenmiş olacaktır. İşletme giderleri düşük olan eko tasarım kapalı çevrim bir kurutma sistemi ortaya konmuştur.
Effects of kinesio taping on static balance performance and muscle activity in children with developmental coordination disorder: a single-group pretest-posttest study
Authors: Li Li-Liang , Chen Fu-Chen
Published: August 2023

Objective: To compare the effects of various kinesio tape applications on static balance and muscle activity in children with developmental coordination disorder. 
Methods: Four taping conditions were applied to 48 children with developmental coordination disorder: no taping, gastrocnemius taping, tibialis anterior taping; and peroneus longus taping. Postural sway and electromyographic data were assessed, with eyes closed (30 s), standing still in 2-leg stance, dominant-leg stance, and non-dominant-leg stance.
Results: Kinesio taping significantly reduced postural sway in both anteroposterior and mediolateral directions for dominant-leg stance and non-dominant-leg stance, but not 2-leg stance. During single-leg stances, anteroposterior sway was significantly lower for the gastrocnemius taping condition than for the no taping, tibialis anterior and peroneus longus taping conditions, and significantly lower in the tibialis anterior and peroneus longus taping conditions than in the no taping condition (gastrocnemius < tibialis anterior = peroneus longus < no taping). In addition, mediolateral sway was significantly lower in the tibialis anterior and peroneus longus taping conditions than in the no taping and gastrocnemius taping conditions, and significantly lower in the gastrocnemius taping condition than in the no taping condition (tibialis anterior = peroneus longus < gastrocnemius < no taping). Electromyographic data showed that muscle activity was significantly greater only for muscles where kinesio tape was applied.
Conclusion: Various kinesio tape applications can differentially reduce postural sway and increase muscle activity during single-leg stances in children with developmental coordination disorder.
An Application of Data Envelopment Analysis in the Selection of the Best Response for the Drilling of Carbon Fiber-reinforced Plastic Composites
Authors: Adedeji Wasiu Oyediran , Odusoro Salome Ifeoluwa , Adedeji Kasali Aderinmoye , Rajan John , Oke Sunday Ayoola , Oyetunji Elkanah Olaosebikan , Nwankiti Ugochukwu Sixtus
Published: August 2023

In the drilling operation, defects such as delamination at exit and entry are very disturbing responses that impact the efficiency of the drilling process. Without control, an exponential growth in the amount of drilled components with defect quantities may result. Thus, the process engineer has input in attaining the desired production levels for components in the drilling process. Consequently, this article deploys a novel method of data envelopment analysis to evaluate the relative efficiency of the drilling process in reducing the defects possible in the producing components from the CFRP composites. The high-speed steel drill bits were utilized to process the CFPs, while the responses considered are the entry and exit determination, thrust force, and torque, among others. Literature experimental data in twenty-seven experimental counts were summarized into fewer groups and processed through the data envelopment analysis method. The results show that capturing the CFRP composite responses is feasible, providing an opportunity for enhanced efficiency and a situation where undesirable defects in the CFRP composite production process may be eradicated. The article’s uniqueness and primary value are in being the foremost article in offering an updated vast representation of the comparative efficiency of CFRP composite parameters within the literature for the composite area. The work adds value to the CFRP composite literature by envisaging and understanding the comparative efficiency for the parameters, identifying and separating the best from the worst decision-making unit. It also reveals how the parameters are linked by their relative placements. The article's novelty is that using data envelopment to compare the efficiency in reducing drilling defects such as entry and exit determination, among others. The method’s utility is to provide information for cost-effective drilling operations during the planning and control phases of the operation.
A conceptual framework combining environmental worldview, organizational learning, and strategic planning contributing to sustainable development
Authors: Ong Kim Kui Daniel , Pramono Rudy
Published: August 2023

This study aims to develop a framework that helps organizations to fulfill their environmental and social responsibility amid constraints in selecting which stakeholders’ interest comes first and the essential to have an evolved strategic planning that can accommodate broader systemic planning and practice that will yield authenticity in business sustainability with components of environmental worldview of its leaders and organizational learning in the framework. This research uses the method of literature review with the data from interviews and content analysis of the report from one organization that has successfully implemented social and environmentally friendly practices. Based on an in-depth review of literatures on worldview, organizational learning, and strategic planning, and with empirical study from one organization, a conceptual framework by combination of the existing concepts is produced to enable an integration of theories in a range of possible actions for organizations to achieve sustainable development. The result from this research’s framework will allow further study to be carried out in the future to verify associations between existing concepts or variables within the framework, and to produce next empirical results in supporting those theories being reviewed in this paper.
THE EFFECT OF BORON AND IAA APPLIED TO SUNFLOWER GROWED AS A SECOND PRODUCT ON SEED SETTING
Authors: Gölkaya Samet , Tamkoç Ahmet
Published: August 2023

This research was carried out on the second crop oil sunflower, which was planted directly on the stubble in the Central Anatolia region.  Increasing doses of boron (4.2 gr, 8.5 gr, and 16.8 gr) and increasing doses of IAA (12 ppm, 16 ppm, and 20 ppm) were applied to leaves of sunflower at R2 and R3 development stages of sunflower in order to increase the number of full seeds (Pieces/Capitulum) of the second crop oil sunflower. The data obtained from the experiment with 4 replications were evaluated statistically, and the difference between them was significant at the p<0.05 probability level. However, the difference between the potential seed number (Pieces/Capitulum) was insignificant. While 4.2 gr and 8.5 gr boron doses from the boron doses applied plots and 20 ppm IAA dose from the IAA applied plots had the highest grain yields, the lowest seed setting was observed in the 16.8 gr boron applied plots and the 12 ppm and 16 ppm IAA applied plots. It has been concluded that the IAA used in the research has both positive and negative effects on productivity against stress conditions created by environmental factors.
Climate change and its adaptation strategies on tea plantation in West Java, Indonesia
Authors: Fatawa Muhammad Ihsan , Santosa Edi , Hapsari Dhika Prita , Krisantini
Published: August 2023

Climate change, i.e., changing rainfall refers to drought and excess rainfall, is known to affect the growth and yield of tea production in many regions. However, research on the impact of climate change on tea plantations in Indonesia is still limited. The study aimed to evaluate the impact of changing rainfall on the productivity of tea plantation at Cianjur, West Java. The data was collected from interviews, field data, and company records from April to July 2022. The results showed that changing rainfall of both limited rainfalls during El Nino and excess rainfall during La Nina affected the tea production. Annual tea productivity declined during both climatic events. Shortage of water during El Nino primarily reduced crop growth, while excess rainfall during La Nina reduced the capacity of tea pickers and increased labor for crop maintenance. Failure to adapt to the direct and indirect impacts of climate change could contribute to declining tea production in Indonesia. Thus, comprehensive action is needed including capacity building in human resources, water management, and microclimate adaptation such as shading plants and tolerant clones to sustain tea production under climate change events.
Agronomic assessment of three spice plants as understorey crops in oil palm (Elaeis guineensis Jacq.) plantation
Authors: Edvanido Hijrianto , Kurniawati Ani , Yahya Sudirman
Published: August 2023

Utilization of land with intercrop plants can support the productivity of the land. The wide spacing of oil palm plants can be used to plant intercrops. Spice plants such as red ginger, turmeric, and cardamom are examples of intercropping plants under the shade of oil palm. This study aimed to determine the adaptability of red ginger, turmeric, and cardamom as understorey plants of different oil palm ages. The research was carried out from February to November 2021 at Sekernan, Muaro Jambi, Jambi. The study consisted of three experiments to investigate three spice plants. Each experiment used a randomized complete block design (RCBD) with oil palm ages as treatments, namely 0, 5, 10, 15, and 20 years. Variables observed included light intensity, plant height, tiller number, leaf number, and rhizome weight. The red ginger and turmeric were considered as adaptive plants to understorey conditions due to the yield of > 60% in 15-year-old oil palm trees than those grown in non-shade conditions. Production levels of red ginger and turmeric were determined by the number of tillers and leaves. The cardamom plant under oil palm shade produced a better yield than that in control. This implies that all three spices are suitable as intercrop plants under oil palm plantations.

Keywords: cardamom; low light intensity; red ginger; shade stands; turmeric
EKSEKUSI PERJANJIAN KREDIT DENGAN JAMINAN FIDUSIA DI ERA PANDEMI (TELAAH KAJIAN MASLAHAH MURSALAH)
Authors: Rofiqi Imam , Rusfandi Rusfandi , Anita Anita
Published: August 2023

The government has a program for small entrepreneurs in terms of activating the provision of credit to weak economic groups for the welfare of people's lives. Credit granting programs with a Fiduciary system can help credit recipients and credit providers. If the guarantee right can be executed quickly with a simple, efficient process and contains legal certainty, this is one of the parameters of a material debt guarantee. This research method uses the Juridical Empirical method, which is an approach taken to analyze the effectiveness of a regulation/legislation or existing law. In this case the approach is used to analyze qualitatively the implementation of fiduciary guarantees in Indonesia. This study uses primary data, namely data obtained directly from the field through an interview process and secondary data, namely examining various legal materials through library research. The analysis used in this research is qualitative analysis which draws conclusions using deductive analysis. Fiduciary Guarantee Law Number 42 of 1999 regulates the execution of Fiduciary Guarantees in Indonesia where there are various variations of the execution, therefore the parties can choose which execution model they want. However, in practice how to carry out the execution of fiduciary guarantees when there are problem loans, many still do not know, especially the implementation in pawnshops, which in fact have just handled the fiduciary system installment credit program. Which model is used by creditors throughout Indonesia. It is hoped that by knowing the system, model or method of executing fiduciary guarantees in this study, people will know more about the ins and outs, their rights and the consequences when taking credit with fiduciary system installments to creditors.
QUALIDADE DE VIDA DOS ACADÊMICOS DE ENFERMAGEM DA UNIVERSIDADE ESTADUAL DE RORAIMA
Authors: Pinto Vitor Sousa , Barros Francisco Railson Bispo de , Marinho Marcella Lima
Published: August 2023

A Qualidade de Vida (QV) é o reflexo da percepção do indivíduo quanto aos aspectos físico, psíquico e social de sua vida, variando de forma positiva ou negativa a depender do contexto em que esteja inserido. Assim, este estudo objetivou identificar o nível de Qualidade de Vida do discente de enfermagem da Universidade Estadual de Roraima. Trata-se de uma pesquisa descritiva, transversal e de abordagem quantitativa com 55 acadêmicos do curso superior de enfermagem. A coleta dos dados ocorreu entre os meses de novembro de 2022 e abril de 2023. Aplicou-se questionário para caracterização dos dados sociodemográficos, acadêmicos, sono, atividade física e alimentação. A percepção da Qualidade de Vida foi avaliada por meio do instrumento WHOQOL-Bref. Os dados foram tabulados em planilhas do Excel 2020 e analisados a partir do software JAMOVI®. Os resultados preliminares indicam que a média de idade dos discentes foi de 22,6 anos (dp=2,6), prevalecendo os indivíduos do gênero feminino, cor parda, solteiro, sem filhos, residindo na capital, carro como principal meio de transporte, morando com os pais, sem atividade laboral, satisfeitos com o curso, mantendo atividade física regular, sem alimentação saudável e com média de sono de 6,7 horas (dp=1,4). Referente aos escores de QV, apenas o Domínio Físico se mostrou insatisfatório, e a média geral foi de 60,2. Apesar da Qualidade de Vida geral se mostrar satisfatória, alguns aspectos merecem evidência, como a qualidade da alimentação e do sono, fatores que estão repercutindo de forma negativa no Domínio Físico dos acadêmicos.
AVALIAÇÃO DO COMPORTAMENTO E EFEITO DO FOGO EM QUEIMA CONTROLADA DE CAPOEIRAS (VEGETAÇÃO SECUNDÁRIA) NA REGIÃO SUL DO ESTADO DE RORAIMA
Authors: Jesus Amanda Nathália Melo de , Pereira Yasmin Alencar , Barni Paulo Eduardo
Published: August 2023

Os incêndios florestais são uma das maiores ameaças à conservação da biodiversidade das florestas, por isso é fundamental o estudo do comportamento do fogo em determinado tipos de vegetações. Em uma área de capoeira (floresta secundária) de 1 ha e de ~3 (três) anos de abandono foram demarcadas 9 parcelas medindo 2 x 4 m (8 m2), separadas por aceiros de um 1 metro de largura entre elas. Na primeira fase, foi realizada a identificação botânica de todos os indivíduos arbóreos com Diâmetro da Base (DB = 1 m do solo) ≥ 1 cm dentro das parcelas. Na segunda fase, as parcelas foram incendiadas e avaliou-se: (1) dados meteorológicos (temperatura do ar, umidade relativa do ar e velocidade do vento); (2) umidade do material combustível; (3) área incendiada; e, (4) velocidade de espalhamento do fogo. Foram identificadas 18 espécies pertencentes à 18 gêneros, sendo que as parcelas 2, 3 e 7 apresentaram indivíduos apenas no extrato inferior. As espécies Brachiaria brizantha e capim Rabo-de-égua, dominando o extrato inferior, foram as mais frequentes em 100% das parcelas. Apenas a parcela 5 queimou sua área completamente, enquanto as outras queimaram apenas 2,97 m2, em média. A maior velocidade de espalhamento foi de 0,0079 m.s-1 obtida na parcela 4, enquanto a menor velocidade foi medida na parcela 8, sendo a velocidade média de 0,0054 m.s-1. As condições ambientais determinadas pelas variáveis meteorológicas influenciaram fortemente o comportamento do fogo.
ASSOCIAÇÃO ENTRE USO DE RECURSOS ERGOGÊNICOS FARMACOLÓGICOS E MOTIVAÇÃO PARA A PRÁTICA DE MUSCULAÇÃO EM ADULTOS DA CIDADE DE BOA VISTA-RR
Authors: Sousa Guilherme Rhairon Gomes , Pinto André de Araújo
Published: August 2023

O objetivo desse estudo foi verificar a associação entre o uso de recursos ergogênicos farmacológicos (REF) e a motivação para a prática de musculação em adultos da cidade de Boa Vista - RR. Trata-se de um estudo de delineamento transversal conduzido em 516 praticantes de musculação em cinco academias de Boa Vista. Foram coletadas informações sociodemográficas, tempo de prática de musculação e fatores motivacionais (condicionamento físico, hipertrofia, qualidade de vida, saúde e estética). O uso de REF foi avaliado a partir da seguinte questão: “você faz uso de recursos ergogênico?”, cujas opções de respostas foram “sim” e “não”. Dos 516 participantes (28,19 ± 8,58 anos), a maioria era constituída do sexo feminino (51,2%). A principal motivação para a prática da musculação foi a estética (32,8%), seguida da saúde (21,9%). Dos participantes que faziam uso de REF, a maioria tinha a estética (23,6%) e a hipertrofia (17,2%) como motivação para a prática  da musculação. Concluiu-se que a estética e a hipertrofia constituem os fatores associados ao uso de REF nos praticantes de musculação da cidade de Boa Vista.
ANESTESIA HIPNÓTICA EM PEQUENAS CIRURGIAS
Authors: Eda Júnior Tetsuo , Diniz Rachel Pereira , Silva Gabryely Kettane Freitas , Souza Gabriel Catunda de , Pereira Thiago Cesar Reis
Published: August 2023

Trata-se de um estudo do tipo de revisão integrativa, sendo utilizado evidências e informações secundárias, com o objetivo de descrever sobre a utilização da anestesia hipnótica em pequenas cirurgias. Foram selecionados 10 estudos sobre a hipnoterapia como técnica alternativa e complementar ao uso de anestesia geral e local em pequenas cirurgias. De acordo com a análise realizada nas pesquisas, foi possível concluir que a hipnose é uma técnica alternativa para o controle da dor e da ansiedade em pequenas cirurgias. No entanto, seus efeitos sobre os resultados pós-operatórios ainda não estão claros.
O PROCESSO DE NATURALIZAÇÃO À LUZ DO DIREITO INTERNACIONAL
Authors: Rodrigues Nathália Karoline Gomes , Almada Tatiana Sousa Silva de
Published: August 2023

O processo de naturalização de estrangeiros no Brasil é regulamentado pelo direito internacional e, portanto, deve estar em consonância com as normas internacionais de direitos humanos. Recentemente, a Portaria nº 623/2020 estabeleceu novas normas e requisitos para o processo de naturalização, gerando controvérsias insegurança jurídica e potenciais violações aos direitos humanos dos solicitantes. Nesse contexto, este trabalho tem o objetivo de analisar as controvérsias no processo de naturalização à luz do direito internacional, com foco na fase de requerimento, sob a influência da Portaria nº 623/2020. Para tanto, serão apresentados os principais desafios e controvérsias enfrentados pelos solicitantes de naturalização, bem como as implicações políticas e sociais da nova legislação. Além disso, será destacada a importância da proteção dos direitos humanos no contexto migratório e da necessidade de se revisar a Portaria nº 623/2020 em conformidade com os princípios do direito internacional. Referente aos aspectos metodológicos, na pesquisa bibliográfica utilizou-se uma abordagem qualitativa, enquanto a análise e interpretação dos dados recorreu à utilização de métodos dedutivos. Por fim, a pesquisa teve como resultado a necessidade de reforçar uma revisão da Portaria nº 623/2020, à luz dos princípios do direito internacional e da proteção dos direitos humanos.
PERFIL EPIDEMIOLÓGICO DOS USUÁRIOS DA PROFILAXIA PÓS-EXPOSIÇÃO AO VÍRUS DA IMUNODEFICÊNCIA HUMANA
Authors: Assunção Francisco Lucas Galeno , Vasconcelos Márcia Santos Carneiro , Almeida Joelson dos Santos , Cardoso Jonas Alves , Barros Cassandra Mirtes de Andrade Rêgo , Da Silva Naylla Amorim Gonçalves , Sousa Kayo Henrique Jardel Feitosa , Miranda Maria do Rosário Costa
Published: August 2023

A Profilaxia Pós-Exposição (PEP) ao Virus da Imunodeficiência Humana (HIV) trata-se de uma urgência médica que deve ser realizada durante 28 dias com medicamentos específicos em indivíduos que tiveram uma exposição com materiais biológicos e situações específicas considerados de risco no intervalo de até 72 horas em indivíduos não reagentes ao vírus do HIV. Objetivo: descrever o perfil epidemiológico dos usuários da PEP no município de Parnaíba, Piauí. Metodologia: Trata-se de um estudo transversal retrospectivo com abordagem quantitativa dos casos de pessoas residentes em Parnaíba, que utilizaram a PEP no período do estudo de 2017 a 2021 analisados por estatística descritiva. Resultados: Foram registrados 202 pacientes que utilizaram a PEP. Dentre estes a maioria foram homens cis com 129 (64%), na faixa etária de 30 a 59 anos foi de (49%) nos casos, a orientação sexual de héteros com (44%), a maioria dos pacientes possuíam o ensino médio (62%), a raça/cor foi maior em pardos (52%). O tipo de exposição mais ocorrente foi sexo consentido (79%), realizaram o tratamento sem intercorrência (84%) dos casos, 62% utilizaram álcool e/ou outras drogas e maioria dos pacientes (57%) referiam não conhecer a situação sorológica dos seus parceiros sexuais. Conclusão: A PEP tem sido uma das formas de prevenção combinada que minimiza as possibilidades de infecção pelo HIV. Percebeu-se que o aumento da população adulta-jovem tem buscado a prevenção, possivelmente devido as práticas consideradas de risco que apresentam maior ocorrência entre os casos.
Depressão em idosos
Authors: Diniz Breno Satler de Oliveira , Rodrigues Valeska Marinho
Published: August 2023

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Titanium Wind Tunnel Balance Leveraging Additive Manufacturing
Authors: Burns Devin E. , Parker Peter A.
Published: August 2023

Titanium force transducers have among the highest strength–to–Young’s modulus ratios of common transducer materials. This can be leveraged to increase the sensitivity of the transducer relative to other materials or to increase the structural safety factor of the transducer for a given sensitivity. It is surprising then that no titanium wind tunnel balances have been reported in the literature or produced by NASA. With the increasing maturation of additive manufacturing technology, this work explores additively manufacturing a titanium wind tunnel balance. Additive manufacturing of the balance was completed in less than 1 week. Then, several secondary finishing and machining operations were performed to finalize the balance geometry, and it was strain gaged and calibrated. Calibration results confirm that the titanium balance has approximately 68% higher output compared to a steel balance of identical geometry and applied load. Based on the calibration results, hysteresis, pure error, and accuracy of the titanium balance are reported. These performance characteristics are comparable to conventionally manufactured state-of-the-art steel balances.
Novel Approach to Autonomous Lunar Localization and Timing
Authors: D’Onofrio Fabio , Zanetti Renato
Published: August 2023

The ability of a deep space spacecraft to estimate its position, velocity, and clock errors without external clock error estimation is investigated. A novel approach to onboard estimation of clock errors is proposed. The effects of clock bias and drift on spacecraft position and velocity errors are derived. These derived equations are leveraged to design a Kalman filter that processes optical measurements along with one-way ranging or two-way position updates from the ground. Simulations are performed to numerically validate the proposed approach and show good localization and timing estimation performance even with lengthy tracking data gaps.
O impacto das tecnologias leves na assistência de enfermagem ao pré-natal
Authors: Campagnoli Yuri Moreira , Ghiraldelli Daniel , Pfaffenbach Grace , Castro Cristiane Pereira de , Silva Debora Luiza da , Luciano Maria Aparecida de Lima , Gomes Luis Eduardo Miani
Published: August 2023

Objetivo: Identificar o impacto das tecnologias leves na assistência de enfermagem nos cuidados pré-natais e os reflexos no processo de internação hospitalar, com foco à assistência prestada a gestante. Revisão bibliográfica: A tecnologia vem tendo enormes avanços em meio há questões humanizadas, e a cada dia possui maiores avanços na área da saúde, tornando assim o uso da tecnologia leve algo necessário para realização de todo o processo de cuidado. enfermagem é uma área que pode fazer o uso da tecnologia pesada, mas a sua base é a tecnologia leve, onde o enfermeiro tem como uma de suas funções e bases de aprendizado a educação em saúde, que é um tanto que imprescindível, e deve ser usada a todo o momento, tornando-se ferramenta indispensável no emprego das tecnologias leves. Considerações finais: Percebe-se que a enfermagem é fundamental na promoção do cuidado ao recém-nascido, pois a enfermagem tem a capacidade de promover a proteção e segurança no processo gestacional, garantindo maior seguridade e redução de taxas de internações, assim empregando as tecnologias leves.
Karakteristik pasien yang menjalani pemeriksan Inspeksi visual asetat (IVA) di Puskesmas Manguharjo
Authors: Khumaira Dinda Selvina , Yunus Moch. , Hapsari Anindya
Published: August 2023

Latar belakang: Pada tahun 2016 di Indonesia tercatat 999.156 jiwa dan 98.000 jiwa mengalami kejadian fluor albus. Pada tahun 2013, tercatat 75% remaja di Jawa Timur mengalami fluor albus minimal sekali. Data dari Puskesmas Manguharjo akhir tahun 2021 tercatat sekitar 80 pasien mengalami fluor albus. Penelitian ini bertujuan untuk meneliti gambaran karakteristik pasien IVA di Puskesmas Manguharjo. Metode: Penelitian ini merupakan studi kuantitatif dengan pendekatan deskriptif analitik, dilakukan pada Bulan Januari sampai dengan Maret 2022. Sebanyak 47 pasien yang menjalani pemeriksaan IVA di Puskesmas Manguharjo diikutsertakan dalam penelitian. Data diperoleh melalui wawancara dan observasi, dan dianalisis menggunakan SPSS. Hasil: Penelitian ini dilakukan pada 47 responden dan mendapatkan hasil terkait usia, kejadian fluor albus, dan frekuensi ganti pembalut. Kesimpulan: Sebagian besar responden berusia 20-30 tahun dan 35 responden mengalami fluor albus. Mayoritas responden menggunakan celana dalam berbahan nilon dan memiliki kebiasaan mengganti pembalut kurang dari tiga kali sehari.
Ekstrak Rimpang Jeringau Merah (Acorus sp) Terhadap.Daya Hambat Pertumbuhan Staphylococcus aureus Dan Escherichia coli
Authors: Chairunnisa Putri Ayudya , Purwanti Nera Umilia , Iswahyudi Iswahyudi
Published: August 2023

Latar Belakang : Tanaman Jeringau merah (Acorus sp) .termasuk dalam famili Acoraceae merupakan keluarga tanaman keladi atau talas-talasan yang tidak berkayu dan hidup di tempat berair (semiakuatik), dan .salah satu tanaman endemik Kalimantan Barat. Jeringau merah memiliki anti infeksi, antiinflamasi, anti-beracun, penurun panas, pencahar urin, anti-kusta, anti-sifilis, antioksidan, perbaikan otak, hipertensi dan perlindungan saraf, sebagai obat perut, diare berdarah dan penyakit kulit.. Jeringau merah mengandung senyawa flavonoid, fenol, alkaloid, terpenoid yang memiliki aktivitas antimikroba. Oleh sebab itu, peneliti ingin mengetahui ada tidaknya aktivitas penghambatan terhadap pertumbuhan mikroba dari ekstrak jeringau merah. Tujuan : mengidentifikasi literatur mengenai aktivitas antibakteri terhadap Staphyloccus aureus dan Escherichia coli ekstrak Jeringau merah. Metode : penelusuran literature review. Artikel diperoleh berasal dari database dan search egine Google Scholar, Research Gate dan Pubmed. Kata Kunci yang digunakan adalah uji aktivitas antibakteri.ekstrak jeringau merah (Acorus sp) terhadap pertumbuhan Staphylococcus aureus. dan Escherichia coli. Analisa yang digunakan adalah analisa SPIDER. Hasil : literature review ditemukan 7 artikel yang sesuai terhadap kriteria yang diinginkan. Diperoleh hasil mengenai aktivitas antibakteri, diameter zona hambat terbaik dan perbandingan zona hambat dari ekstrak jeringau merah sebagai antibakteri
Random terpolymer of CO2, 1,3-butadiene and epoxides: synthesis, topology, fluorescence and degradability
Authors: Wang Zi , Yue Sicong , Chen Kaihao , Ling Jun , Ni Xufeng
Published: August 2023

The utilization of carbon dioxide (CO2) as a feedstock is consistently attractive, especially in the preparation of sustainable polymeric materials. Here, a terpolymer of CO2, 1,3-butadiene (BD) and epoxides is synthesized via an intermediate named α-ethylidene-δ-vinyl-δ-valerolactone (EVL). The terpolymer with number-average molecular weight (Mn) up to 7.8 kg/mol and dispersity (Đ) of 2.4 is obtained from cationic ring-opening copolymerization of EVL with cyclohexene oxide (CHO). The reactivity ratios of EVL and CHO are determined as 0.01 and 1.07, respectively, suggesting random characteristic of the terpolymer. The preserved C=C double bonds from BD allow further topology alternation of the terpolymer by photoinitiated crosslinking. The yielded networks are fluorescent and degradable. This method offers enhanced versatility to the synthesis and additional functionalization of CO2-based polymers.
3D Printable Modular Soft Elastomers from Physically Crosslinked Homogeneous Associative Polymers
Authors: Kim Myoeum , Nian Shifeng , Rau Daniel , Huang Baiqiang , Zhu Jinchang , Freychet Guillaume , Zhernenkov Mikhail , Cai Li-Heng
Published: August 2023

Three-dimensional (3D) printing of elastomers enables the fabrication of many technologically important structures and devices. However, there remains a critical need for the development of reprocessable, solvent-free soft elastomers that can be printed without the need for post-treatment. Here, we report modular soft elastomers suitable for direct ink write (DIW) printing by physically crosslinking associative polymers with a high fraction of reversible bonds. We design and synthesize linear-associative-linear (LAL) triblock copolymers; the middle block is an associative polymer carrying amide groups that form double hydrogen bonding, and the end blocks aggregate to hard glassy domains that effectively act as physical crosslinks. The amide groups do not aggregate to form nanoscale clusters and only slow polymer dynamics without changing the shape of the linear viscoelastic spectra; this enables molecular control over energy dissipation by varying the fraction of the associative groups. Exploiting the more ordered microstructures afforded by block copolymer self-assembly increases the network stiffness by >100 times without significantly compromising extensibility. We use a high-temperature DIW printing platform to print these LAL polymers and manufacture complex, highly deformable 3D structures. Our printing process uses melt processing and is solvent-free, and the printed parts do not require any post-print processing. We create elastomers with Young’s moduli ranging from 8 kPa to 8 MPa while maintaining tensile breaking strain around 150%. Our elastomers represent the softest melt reprocessable materials for DIW printing. The developed LAL polymers synergize emerging homogeneous associative polymers with high fraction of reversible bonds and classical block copolymer self-assembly to form a dual-crosslinked network, providing a versatile platform for the modular design and development of soft, melt reprocessable elastomeric materials for practical applications.
Free Energy Profile Decomposition Analysis for QM/MM Simulations of Enzymatic Reactions
Authors: Pan Xiaoliang , Van Richard , Pu Jingzhi , Nam Kwangho , Mao Yuezhi , Shao Yihan
Published: August 2023

In enzyme mechanistic studies and mutant design, it is highly desirable to know the individual residue contributions to the reaction free energy barrier. In this work, we show that such free energy contributions from each residue can be readily obtained by post-processing ab initio quantum mechanical molecular mechanical (ai-QM/MM) free energy simulation trajectories. Specifically, through a mean force integration along the minimum free energy pathway, one can obtain the electrostatic, polarization, and van der Waals contributions from each residue to the free energy barrier. Separately, a similar analysis procedure allows us to assess the contribution from different collective variables along the reaction coordinate. The chorismate mutase reaction is used to demonstrate the utilization of these two trajectory analysis tools.
Expanding the chemical space using a Chemical Reaction Knowledge Graph
Authors: Rydholm Emma , Bastys Tomas , Svensson Emma , Kannas Christos , Engkvist Ola , Kogej Thierry
Published: August 2023

In this work, we present a new molecular de novo design approach which utilizes a knowledge graph encoding of chemical reactions, extracted from the publicly available USPTO (United States Patent and Trademark Office) dataset. Our proposed method can be used to expand the chemical space by performing forward synthesis prediction on the knowledge graph and can generate libraries of de novo compounds along with a valid synthetic route. The forward synthesis prediction of novel compounds involves two steps. In a first step, a graph neural network-based link prediction model is used to suggest pairs of existing reactant nodes in the graph that are likely to react. In a second step, product prediction is performed using a molecular transformer model to obtain the potential products for the suggested reactant pairs. We achieve a ROC-AUC score of 0.861 for link prediction in the knowledge graph and for the product prediction a top-1 accuracy of 0.924. The method’s utility is demonstrated by generating a set of de novo compounds by predicting high probability reactions in USPTO. The generated compounds are diverse in nature and many exhibits drug-like properties. Further, evaluation of the potential activity using a quantitative structure–activity relationship (QSAR) model suggested presence of potential dopamine receptor D2 (DRD2) modulators among the proposed compounds. In summary, our results suggest that the proposed method can expand the easily accessible chemical space and identify novel drug-like compounds for a specific target.
PHYTOCHEMICAL VARIABILITY AND ANTIMICROBIAL ACTIVITY OF EXTRACTS OF Citropsis articulata LEAVES FROM THREE TROPICAL FORESTS IN UGANDA
Authors: Wangalwa Rapheal , Lukubye Ben , Olusoji Ajayi Clement , Peter Lyimo Emanuel , Apio Olet Eunice , Kagoro-Rugunda Grace , Umba Tolo Casim
Published: August 2023

Empirical evidence of the presence of bioactive compounds in plants is indispensable, given that medicinal plants play a pivotal role in the quest for new antimicrobials. In this study, leaves of Citropsis articulata from three forest reserves (Mabira, Budongo, and Kibale) in Uganda were extracted with distilled water and methanol using infusion and maceration methods, respectively. The total phenolic (TP), total flavonoid (TF), total alkaloid (TA) and total saponin (TS) contents of the extracts were evaluated using UV-Vis spectrophotometric based methods before the fingerprint of each extract was established using high-performance liquid chromatography. In vitro antimicrobial activities of the extracts were examined against standard strains of common pathogenic microbes, including Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, and Candida albicans using agar well diffusion and microtitre plate-based assays. Results showed that the methanol extract had a significantly higher content of the secondary metabolites compared to the aqueous extract, with samples from Mabira showing the highest level of TP (68.92 mg GAE/g), samples from Budongo had the highest level of TF (11.28 mg QE/g) and TS (101.94 mg DE/g). In comparison, samples from Kibale showed the highest level of TA (66.29 mg AE/g). In the antimicrobial study, methanol extract showed significantly higher potency than the aqueous extract for all samples from the three locations. The plant extracts showed substantially high potency against Escherichia coli, with samples from Mabira exhibiting the maximum zone of inhibition (29.5±0.5 mm) at 50% w/v and lowest minimum inhibitory concentration (MIC) of 1.56% w/v. The extracts also demonstrated bactericidal (MBC) and fungicidal (MFC) potency against the test microorganisms in the order; Escherichia coli > Staphylococcus aureus > Pseudomonas aeruginosa > Candida albicans. This study demonstrated that Citropsis articulata leaves have potentially potent bioactive compounds that could be explored for future antimicrobial drug development.
LEAF ANATOMY OF YOUNGIA JAPONICA (L.) DC. (ASTERACEAE) FROM PAHANG, MALAYSIA
Authors: Abdul Rashid Zainab Sholehah , Aini Che Amri Che Nurul , Shahari Rozilawati
Published: August 2023

Leaf anatomical and micromorphological studies on Youngia japonica (Asteraceae family) were accomplished. In the North America, this wild plant is consumed as salad as a healthy diet. The whole plant is edible and has been consumed in past years especially during famine. The Chinese community has been using this plant to perform blood cleansing, to cure sore throat, diarrhoea, mastitis, shingles, sprains, and bruises. Since there is yet any comprehensive study on the taxonomic study of Y. japonica in Kuantan, this study aims to investigate and examine its leaf anatomical and micromorphological characteristics that can be used as a complete guidance for its identification and additional data for its species classification. The methods involved in the leaf anatomy included a cross sectioning method on the petiole, midrib, lamina, and margin using a sliding microtome, clearing of venation using basic fuchsin, and epidermal peel methods using Jeffrey solution. The micromorphology of the leaf was observed under a scanning electron microscopy (SEM). The result of the characteristics of leaf anatomical and micromorphological studies for Y. japonica found the type of vascular bundle at petiole which was an opened system, noncontinuous ring of separated vascular bundle arranged in arc-shaped with additional vascular bundles, there were presence of mucilage cells, incomplete marginal venation, anomocytic stomata at leaf epidermis, granules and crust of wax, and multicellular trichomes with different ended and capitate glandular trichome. In conclusion, the findings have shown that the anatomical and micromorphological characteristics have their taxonomic value and can be useful in the identification, differentiation, and classification of the plant at the species level.
EFFECTS OF GUANO MANURE ON HEIGHT GROWTH AND FOLIAR NUTRIENT CONCENTRATIONS OF SELASIH (OCIMUM TENUIFLORUM L.)
Authors: Abdul Rahman Nurhasliyana , Ab Majid Nik Muhamad , Syahmi Salleh Mohd
Published: August 2023

The herbal industry in Malaysia is facing problem of scarcity of the natural herbs due to excessive exploitation of natural forest. It is therefore necessary to cultivate these herbs and research is urgently needed on its agronomic aspects. A pot trial study was therefore carried with the following objectives: (i) to determine the effects of different organic fertilizer rates on height growth, and (ii) to measure selected foliar and soil nutrient concentrations. Treatments evaluated were: (i) 10% of guano manure mixed with 90% of soil (T1), (ii) 20% of guano manure mixed with 80% of soil (T2), (iii) 30% of guano manure mixed with 70% of soil (T3), (iv) 40% of guano manure mixed with 60% of soil (T4), (v) 50% of guano manure mixed with 50% of soil (T5), (vi) 60% of guano manure mixed with 40% of soil (T6), (vii) 70% of guano manure mixed with 30% of soil (T7), (viii) 80% of guano manure mixed with 20% of soil (T8), (ix) 90% of guano manure mixed with 10% of soil (T9), and (x) Soil without guano manure (control) (T10). The experiment was conducted using a Completely Randomize Design (CRD) with five replications. Plant height for each treatment was recorded on monthly basis for four months duration. Selected nutrient concentrations in the plant leaves after harvest and in the soil before planting and after harvest along with the soil pH were analysed. Soil total N was determined using Kjeldahl method while total P was determined using Aqua regia method. The exchangeable K, Ca, Mg, Zn, Cu, and Na were extracted using double acid method and their concentrations determined using atomic absorption spectrophotometry (AAS). Dry ashing method was used for the determination of P, K, Ca, Mg, Zn, Cu, and Na concentrations in plant leaves while total N concentrations was determined using Kjeldahl method. Guano manure showed significant effects on plant height, and concentrations of total N, total P, Ca, Mg and Zn in the leaves. The T3 recorded significantly higher plant height at 76.50 cm while the lowest was in T9 at 50.60 cm. The concentrations of K, Cu and Na on the other hand recorded no significant effects. Nutrient concentrations in the soil after harvest decreased compared to before planting while soil pH increased as level of manure increased in the soil before planting and after harvest. It is advisable to conduct field trial experiment for further study.
In Defense of Moderation
Authors: Goodrich James
Published: August 2023

Many of us believe that if some acts wrongly out of culpably ignorance, they are morally blameworthy to some degree. I offer a defense of this view against the powerful "Liberal Challenge" to the position. My defense proceeds by arguing that facts about a given agent's quality of will can play a different explanatory role in the larger theory of blameworthiness and the structure of exculpation than is often assumed.
Whom Do You Speak For? And How?
Authors: Barnes Michael Randall
Published: August 2023

A lot of subordinating speech has moved online, which raises several questions for philosophers. Can current accounts of oppressive speech adequately capture digital hate? How does the anonymity of online harassers contribute to the force of their speech? This paper examines online abuse and argues that standard accounts of licensing and accommodation are not up to the task of explaining the authority of online hate speech, as speaker authority often depends on the community in more ways than these accounts suggests. Instead I argue that online abusive speech is best understood as collective subordinating speech acts, as their authority is drawn from an ad hoc collective. I argue that anonymity and shared language offer online abusers a path to a type of group-authority that explains the harm their speech is capable of. I close by suggesting that similar considerations are in play for IRL subordinating speech, and that online abuse helps to reveal key features of subordinating speech across mediums that are under-emphasized in the existing literature.