bluuebunny/crossref_metadata_2025 huggingface dataset:
A comparison of laryngeal mask airway-supreme and endotracheal tube use with respect to airway protection in patients undergoing septoplasty: a randomized, single-blind, controlled clinical trial
Authors: Karaaslan Erol , Akbas Sedat , Ozkan Ahmet Selim , Colak Cemil , Begec Zekine
Published: January 2021

Background

There are doubts among anesthesiologists on the use of the Laryngeal Mask Airway (LMA) in nasal surgeries because of concerns about the occurrence of blood leakages to the airway. We hypothesized that the use of LMA-Supreme (LMA-S) in nasal surgery is comparable with endotracheal tube (ETT) according to airway protection against blood leakage through the fiberoptic bronchoscopy, oropharyngeal leakage pressure (OLP), heart rate (HR), mean arterial pressure (MAP), and postoperative adverse events.

Methods

The present study was conducted in a prospective, randomized, single-blind, controlled manner on 80 patients, who underwent septoplasty procedures under general anesthesia, after dividing them randomly into two groups according to the device used (LMA-S or ETT). The presence of blood in the airway (glottis/trachea, distal trachea) was analyzed with the fiberoptic bronchoscope and a four-point scale. Both groups were evaluated for OLP; HR; MAP; postoperative sore throat, nausea, and vomiting; dysphagia; and dysphonia.

Results

In the fiberoptic evaluation of the airway postoperatively, less blood leakage was detected in both anatomic areas in the LMA-S group than in the ETT group (glottis/trachea,p = 0.004; distal trachea,p = 0.034). Sore throat was detected less frequently in the LMA-S group at a significant level in the 2nd, 6th, and 12th hours of postoperative period; however, other adverse events were similar in both groups. Hemodynamic parameters were not different between the two groups.

Conclusion

The present findings demonstrate that the LMA-S provided more effective airway protection than the ETT in preventing blood leakage in the septoplasty procedures. We believe that the LMA-S can be used safely and as an alternative to the ETT in septoplasty cases.

Trial registration

This trial is registered at the US National Institutes of Health (ClinicalTrials.gov) #NCT03903679on April 5, 2019.
Urinary coenzyme Q10 as a diagnostic biomarker and predictor of remission in a patient with ADCK4-associated Glomerulopathy: a case report
Authors: Zhang Yan , Liao Xiaohua , Jiang Yupeng , Lv Xin , Yu Yue , Dai Qin , Ao Liyun , Tao Lijian , Peng Zhangzhe
Published: January 2021

Background

AarF domain-containing kinase 4 (ADCK4)-associated glomerulopathy is a mitochondrial nephropathy caused by mutations in the ADCK4 gene, which disrupt coenzyme Q10 biosynthesis.

Case presentation

We report the case of a 25-year-old female patient with ADCK4-associated glomerulopathy presenting with proteinuria (and with no additional systemic symptoms). A known missense substitution c.737G > A (p.S246N) and a novel frameshift c.577-600del (p.193-200del) mutation were found. We followed the patient for 24 months during supplementation with coenzyme Q10 (20 mg/kg/d – 30 mg/kg/d) and describe the clinical course. In addition, we measured serum and urine coenzyme Q10 levels before and after coenzyme Q10 supplementation and compared them with those of healthy control subjects. The patient’s urinary coenzyme Q10 to creatinine ratio was higher than that of healthy controls before coenzyme Q10 supplementation, but decreased consistently with proteinuria after coenzyme Q10 supplementation.

Conclusions

Although the use of urinary coenzyme Q10 as a diagnostic biomarker and predictor of clinical remission in patients with ADCK4-associated glomerulopathy should be confirmed by larger studies, we recommend measuring urinary coenzyme Q10 in patients with isolated proteinuria of unknown cause, since it may provide a diagnostic clue to mitochondrial nephropathy.
Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells
Authors: Hong Xian , Li Zhi-Xuan , Hou Jie , Zhang Hui-Yu , Zhang Chun-Yan , Zhang Jian , Sun He , Pang Li-Hong , Wang Tao , Deng Zhi-Hui
Published: January 2021

Background

Anterior gradient-2 (AGR2) is a proto-oncogene involved in tumorigenesis and cancer progression. AGR2, predominantly localized in the endoplasmic reticulum (ER), is also a secreted protein detected in the extracellular compartment in multiple cancers. However, the biological functions of intracellular and extracellular AGR2 remain to be elucidated.

Methods

Based on the biochemical structure of AGR2 protein, PANC-1 pancreatic cancer cells stably expressing ER-resident or secreted AGR2 were generated by a lentivirus-mediated stable overexpression system. The capacities of cell proliferation, migration, invasion and survival were assessed in PANC-1 stable cells. Moreover, EGFR expression and activation were determined to explore the possible mechanism of AGR2 roles in pancreatic cancer tumorigenesis.

Results

It was discovered that secreted AGR2, but not ER-resident AGR2, promotes cell proliferation, migration and invasion of PANC-1 cells. Moreover, the data indicated that both the ER-resident and the secreted AGR2 enhance the survival capacity of PANC-1 cells after tunicamycin-induced ER stress and gemcitabine treatment. However, EGFR expression and activation were not found to be involved in AGR2-dependent oncogenic phenotypes in PANC-1 cells.

Conclusions

Secreted AGR2 is predominantly involved in cell proliferation, migration and invasion in PANC-1 pancreatic cancer cells. Both secreted and ER-resident AGR2 contribute to the survival of PANC-1 cells under the challenging conditions. These findings provide insight into how different localizations of AGR2 have contributed to pancreatic cancer growth, metastasis, and drug sensitivity.
Presence of one ecto- and two endoparasite species of the black stork (Ciconia nigra) in Portugal
Authors: Ramilo David W. , Caetano Inês , Brazio Erica , Mira Manuela , Antunes Leonor , da Fonseca Isabel Pereira , Cardoso Luís
Published: January 2021

Background

The black stork (Ciconia nigraLinnaeus, 1758) is a recognized endangered species in Europe and most of the specimens from the Western Palearctic region breed in the Iberian Peninsula. Available works regarding parasites in black storks are scarce. This work reports the presence one ecto- and two endoparasite species from a black stork in Portugal.

Case presentation

A black stork was found in southern Portugal after colliding against electric cables. The specimen did not survive its sustained injuries and a post-mortem exam was performed. During the procedure, several ecto- and endoparasite specimens were found. The collected parasites were lice (Neophilopterus tricolor), nematodes (Desportesius sagittatus) and trematodes (Cathaemasia hians).

Conclusions

Three different species of parasites are reported from a black stork in Portugal. Ecto- and endoparasites ofC. nigrahave not frequently been described in the literature, and this case report is a contribution to the field. Additional studies will be important to better understand the impact that parasites can have onC. nigrahealth and survival.
ACTN1 supports tumor growth by inhibiting Hippo signaling in hepatocellular carcinoma
Authors: Chen Qian , Zhou Xiao-Wei , Zhang Ai-Jun , He Kang
Published: January 2021

Background

Alpha actinins (ACTNs) are major cytoskeletal proteins and exhibit many non-muscle functions. Emerging evidence have uncovered the regulatory role of ACTNs in tumorigenesis, however, the expression pattern, biological functions, and underlying mechanism of ACTN1 in hepatocellular carcinoma (HCC) remain largely unexplored.

Methods

Immunohistochemical analysis of a HCC tissue microarray (n = 157) was performed to determine the expression pattern and prognostic value of ACTN1 in HCC. In vitro loss-of-function study in HCC cells were carried out to investigate ACTN1 knockdown on cell proliferation. In vivo subcutaneous xenograft model and intrahepatic transplantation model were generated to decipher the contribution of ACTN1 in the tumor growth of HCC. Gene set enrichment analysis, quantitative real-time PCR, Co-immunoprecipitation, immunofluorescence and western blotting were performed to identify the underlying molecular mechanism.

Results

It was found that ACTN1 was significantly upregulated in HCC tissues and closely related to llpha-fetoprotein level, tumor thrombus, tumor size, TNM stage and patient prognoses. Knockdown of ACTN1 suppressed in vitro cell proliferation and in vivo tumor growth of HCC cells. Mechanistically, knockdown of ACTN1 increased Hippo signaling pathway activity and decreased Rho GTPases activities. Mechanistically, ACTN1 could competitively interact with MOB1 and decrease the phosphorylation of LATS1 and YAP. The growth-promoting effect induced by ACTN1 was significantly abrogated by pharmacological inhibition of YAP with verteporfin or super-TDU.

Conclusions

ACTN1 is highly expressed in HCC tissues and acts as a tumor promoter by suppressing Hippo signaling via physical interaction with MOB1. ACTN1 may serve as a potential prognostic marker and therapeutic target for HCC.
Patient survey of value in relation to radiology: results from a survey of the European Society of Radiology (ESR) value-based radiology subcommittee
Authors:   European Society of Radiology (ESR)
Published: January 2021

Rationale and methodology

A survey of patients was carried out between January and June 2019, to better understand how patients interpret value in relation to radiology as a means to refining the concept of Value-Based Radiology (VBR) in Europe, ensure radiology’s value is properly weighted in Value-Based Health Care (VBH) metrics, and maximise the value of radiological services to patients. The survey was disseminated via various heads of radiology departments, ESR officers, patient organisations, and ESR website and social media channels.

Results

Responses were received from 400 patients from 22 countries. Whilst most expressed general satisfaction with the radiological services they received, certain aspects of the radiological services they received left room for improvement. Thirty-six percent of respondents reported that they were not satisfied with the information provided about the risks and benefits of procedures, and thirty-three percent reported not being satisfied with the availability of radiologists for consultation, potentially suggesting that some patients lack sufficient information to participate fully in treatment decisions. Patients were often unaware of what information they were entitled to receive. Over eighty percent of respondents were unfamiliar with the concepts of Value-Based Radiology and/or Value-Based Health Care.

Conclusion

In addition to procedural correctness (correct diagnosis, appropriate procedures performed), patients highly value information and communication with their radiologist (information provided about procedures, explanation of results, personal consultation). Lack of communication was found to be a cause of dissatisfaction in many cases. This could suggest a means of improving patient outcomes as measured by Value-Based Health Care metrics.
Feasibility of Monte-Carlo algorithm in comparison with collapse-cone dose calculation algorithm of a commercial treatment planning system in the presence of high-density metallic implant: a dosimetric study
Authors: Bhushan Manindra , Tripathi Deepak , Yadav Girigesh , Kumar Lalit , Chowdhary Rahul Lal , Pahuja Anjali K. , Suresh Tamilarasu , Shukla Sushil Kumar , Mitra Swarupa
Published: January 2021

Background

The number of people with implanted hip prosthesis has grown worldwide. For radiotherapy planning of patients with hip implants, few main challenges are encountered. The aim of the present study was to evaluate the feasibility of different planning algorithms in the presence of high-density metallic implant in the treatment of patients with carcinoma cervix.

Results

It was found that D98% were 44.49 ± 0.11, 44.51 ± 0.13, 44.39 ± 0.22, and 44.45 ± 0.16 Gy for 4FMC6MV (4-field technique calculated with Monte-Carlo algorithm and 6 MV photon energy), 4FMC6MV_WP (4-field technique calculated with Monte-Carlo algorithm and 6 MV photon energy without prosthesis), 4FCC6MV (4-field technique calculated with collapse-cone-convolution algorithm and 6 MV photon energy), and 4FCC6MV_WP (4-field technique calculated with collapse-cone-convolution algorithm and 6 MV photon energy without prosthesis) respectively. Similarly, D2% were 49.40 ± 0.84, 49.05 ± 0.76, 48.97 ± 0.91, and 48.57 ± 0.85 Gray (Gy) for 4FMC6MV, 4FMC6MV_WP, 4FCC6MV, and 4FCC6MV_WP respectively. The present study has not suggested any major difference between the Monte-Carlo (MC) and collapse-cone-convolution (CCC) calculation algorithm in the presence of high-Z metallic implants. Volume of bowel receiving 15 Gy dose has shown a significant difference with prosthesis cases. This study investigates that hip prosthesis creates considerable changes in the treatment planning of cervical malignancies.

Conclusion

CCC algorithm is in good agreement with MC calculation algorithm in the presence of high-density metallic implants in terms of target coverage and avoidance organ sparing except few parameters.
Isolation and characterization of bioactive compounds from Euphorbia cotinifolia
Authors: Jayalakshmi B. , Raveesha K. A. , Amruthesh K. N.
Published: January 2021

Background

Green plants are found to be an effective reservoir for bioactive molecules and can provide appreciable sources of antimicrobial agents. Antibacterial activity of solvent extracts of Euphorbia cotinifolia leaves was tested by agar cup diffusion and broth microdilution methods against some common human pathogenic bacteria viz., Bacillus cereus, Klebsiella pneumonia, Enterobacter aerogenes, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Salmonella typhi. The methanol extract of Euphorbia cotinifolia was subjected to a silica gel column, leading to the isolation of a bioactive compound 1. The structure of compounds was elucidated by spectroscopic techniques and assessed for their antibacterial activity against several human pathogenic bacteria.

Results

The inhibition zone ranged against some common human pathogenic bacteria was 15.25–19.50 mm, 13.50–19.25 mm, 12–18.50 mm, 15–20 mm, and 13–19 mm for ECMF1, ECMF2, ECMF3, compounds 1, respectively. The MIC was found to be in the range 91–729 μg/ml for the fractions. The inhibition range was recorded between 12–19 and 10–14 mm for methanol and ethyl acetate extracts, respectively. K. pneumoniae, E. aerogenes, and B. subtilis were highly susceptible to methanol extract with the maximum inhibition zone of 19 mm. The MIC of the compound 1 against human pathogens was 78–833 μg/ml.

Conclusion

The present study results suggest that tested plant extracts have moderate to potent antibacterial activity due to the occurrence of phenols and flavonoids in the extracts. The defensive property of natural antibacterials is mainly due to the presence of these major groups, vitamins, phenols, flavonoids, and carotenoids. In the present study, biologically active diterpene was isolated and the structures of the new diterpenoids isolated from E. cotinifolia were closely related to an ingenol ester.
Association of mental disorders with SARS-CoV-2 infection and severe health outcomes: nationwide cohort study
Authors: Jeon Ha-Lim , Kwon Jun Soo , Park So-Hee , Shin Ju-Young
Published: January 2021

Background

Epidemiological data on the association between mental disorders and the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) severity are limited.

Aims

To evaluate the association between mental disorders and the risk of SARS-CoV-2 infection and severe outcomes following COVID-19.

Method

We performed a cohort study using the Korean COVID-19 patient database based on national health insurance data. Each person with a mental or behavioural disorder (diagnosed during the 6 months prior to their first SARS-CoV-2 test) was matched by age, gender and Charlson Comorbidity Index with up to four people without mental disorders. SARS-CoV-2-positivity risk and the risk of death or severe events (intensive care unit admission, use of mechanical ventilation and acute respiratory distress syndrome) post-infection were calculated using conditional logistic regression analysis.

Results

Among 230 565 people tested for SARS-CoV-2, 33 653 (14.6%) had mental disorders; 928/33 653 (2.76%) tested SARS-CoV-2 positive and 56/928 (6.03%) died. In multivariable analysis using the matched cohort, there was no association between mental disorders and SARS-CoV-2-positivity risk (odds ratio OR = 0.95; 95% CI 0.87–1.04); however, a higher risk was associated with schizophrenia-related disorders (OR = 1.50; 95% CI 1.14–1.99). Among confirmed COVID-19 patients, the mortality risk was significantly higher in patients with than in those without mental disorders (OR = 1.99, 95% CI 1.15–3.43).

Conclusions

Mental disorders are likely contributing factors to mortality following COVID-19. Although the infection risk was not higher for people with mental disorders overall, those with schizophrenia-related disorders were more vulnerable to infection.
EDITORIAL
Authors: Silva Silvio Bitencourt da , Coelho Arnaldo Fernandes Matos , Weersma Laodicéia Amorim
Published: January 2021

A inovação distribui-se por várias disciplinas e pesquisas no campo da economia, da administração, das engenharias, do direito, entre outras. Em particular, tem atraído atenção de pesquisadores, gestores e formuladores de políticas públicas quanto a seu papel no desenvolvimento econômico e social. [...].
The effect of acute complicated appendicitis on liver function test
Authors: MoulaBux Kulsoom , Parveen Sughra , Iqbal Mazhar , Mehboob Ayesha
Published: January 2021

Objectives: To determine the diagnostic role of hyperbilirubinemia in acute appendicitis like suppurative and gangrenous appendicitis.

Methods: This observational study was conducted at Ward-3, Jinnah Postgraduate Medical Center (JPMC), Karachi from 1st June 2019 to 1st June 2020. Males and females above 12 years of age were included. Serum liver function tests and leukocyte counts were carried out. Appendectomies were done, the operative findings and histopathology reports were noted. Hyperbilirubinemia was related with the stages of appendicitis. Results were analyzed by SPSS version 25.

Results: There were one hundred twenty patients. Thirty-eight (31.66%) were females and eighty-two (68.33%) were males. Age range was 13 to 60 years. Ten patients (8.33%) were between 13 – 20 years, sixty five (54.16%) were 21 to 30 years, thirty (25%) were 31 – 40 years, ten (8.33%) were 41 – 50 years and five patients (4.17%) were above 50 years of age. Sixty-two (51.66%) patients had simple appendicitis and fifty-four (45%) had complicated appendicitis like suppurative (26.66%) and (16.66%) gangrenous appendicitis. Negative appendectomy was found in four (3.33%). Hyperbilirubinemia was found (100%) in gangrenous, (94.12%) in suppurative and (12.3%) in catarrhal appendicitis. Enzymes like Alanine transaminase and Aspartate transaminase were raised (50%) in gangrenous, (50%) in suppurative and (9.67%) in catarrhal appendicitis. TLC was raised in 112 (96.55%) out of 116 patients and total leukocyte count was normal in negative appendectomies.

Conclusions: It is concluded that hyperbilirubinemia is strong diagnostic predictor for complicated appendicitis.\

doi: https://doi.org/10.12669/pjms.37.2.3356

How to cite this:MoulaBux K, Parveen S, Iqbal M, Mehboob A. The effect of acute complicated appendicitis on liver function test. Pak J Med Sci. 2021;37(2):351-354. doi: https://doi.org/10.12669/pjms.37.2.3356

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Development of Multimedia Based on Autodesk Inventor Software on the Concept of Relative Velocity to Increase Students’ Generic Science Skill
Authors: Ariyano Ariyano , Suherman Amay , Akhmadi Handiansyah
Published: January 2021

This research aims to develop autodesk inventor-based multimedia that was designed to increase students’ generic science skill on the application of relative velocity at kinematics and dynamics courses. This study used the mini course method developed by Borg and Gall, including the stage of analysing and planning, developing early product, and validating from the expert and revision the early product. Based on the analysis conducted, it was revealed that there were five indicators that students had difficulties with, including illustrating kinematic diagram, illustrating velocity direction, calculating absolute velocity, illustrating velocity polygon, and calculating velocity based on velocity polygon. Those five indicators were related to six generic science aspects, including modelling, symbolic language, laws of causality, logical consistency, scale awareness, and observation. The developed multimedia consists of nine displays of slider-crank mechanism and eight displays of four-bar mechanisms, using .idw, .iam, and .mp4 formats and has been validated by material and media experts. Based on the judgment from the experts, the inventor-based multimedia was worthy to be applied in the course.
How to enhance your career with teeth whitening
Authors: Symmonds Anna
Published: January 2021

Dental nurse Anna Symmonds on why you are perfectly placed to encourage patients to begin their smile makeover journey
The dynamics of dental nursing
Authors: Mercer Charlotte
Published: January 2021

Charlotte Mercer dropped out of school after failing her first year of A levels, found an advert in the newspaper for an apprentice dental nurse position and, nine years later, she is still doing it…
Ploughing ahead…
Authors: Bissett Julie
Published: January 2021

Julie Bissett considers why we all need the strength of an ox to ensure the profession gets a ‘smile makeover’ this new year
Does perceived social responsibility affect consumer attitudes towards global brands? Lessons from the Nescafé Case in Turkey
Authors: Akcay Ediz Edip , Kooli Kaouther , Gaber Hazem Rasheed
Published: January 2021

This study builds on consumer culture theory, signalling theory and the associative network memory model to investigate the impact of consumers' perceptions of global brands' social responsibility on consumers' attitudes towards brands. A survey was conducted in Turkey using Nescafé
as an example of a global brand. Data from 243 fully completed questionnaires were analysed using SmartPLS. The results from the structural equation modelling indicate that for Turkish consumers, the perceived globalness of the brand contributes to the brand's perceived credibility but has
a negative direct relationship on the perception of the brand's social responsibility. In addition, the local icon value of the brand has positive and significant relationships with the brand's perceived credibility and the brand's perceived social responsibility. This later has a positive
relationship on consumers' attitudes towards the brand. The perceived globalness of the brand is important to develop the perceived credibility of the brand. The paper provides some guidelines for global brands when communicating their social responsibility activities to consumers in emerging
markets.
A Single-Function Model for the Eye’s Crystalline Lens
Authors: Jaimes-Nájera A. , Gómez-Correa J. E. , Coello V. , Pierscionek B. K. , Chávez-Cerda S.
Published: January 2021

In recent work, we showed how the optical response of the human eye’s crystalline lens can be modeled using a single function. We believe that this development will inform designs for applications such as intraocular implant lenses, and that it also has wider potential applications in areas including biomedical optics, ophthalmology and engineering.
AUTHENTIC LEADERSHIP, LEADER ANGER AND FOLLOWER JOB OUTCOMES: A COMPARISON OF ANGRY VS. NON-ANGRY LEADERS
Authors: BAKER Nevra
Published: January 2021

This study investigates the effects of authentic leadership and leader anger on follower job outcomes of affective organizational commitment, trust in leader, and job satisfaction. In order to test the hypotheses of the study, an experiment and a survey were conducted, respectively. In the experiment, four different fictive leader types were constructed, and respondents were asked to answer questions about these leaders with the assumption that they worked with these fictional leaders. The findings of this study reveal that authentic leaders aroused higher levels of affective organizational commitment, trust in leader, and job satisfaction by their followers as compared to inauthentic leaders. Furthermore, both authentic and inauthentic leaders who displayed anger aroused lower levels of affective organizational commitment and trust in leader by their followers as compared to their counterparts who did not; and only authentic leaders who displayed anger aroused lower levels of job satisfaction as compared to their non-angry counterparts.
Study on Tool Deterioration in Machining with Minimum Quantity Lubrication (MQL) Condition
Authors: Qoryah Rika Dwi Hidayatul , Luviandy Allen , Darsin Mahros
Published: January 2021

This study aims to observe the tool deterioration following application of minimum quantity lubrication method (MQL). The designed MQL system is completed with an Arduino controller system which was able to be either manually-controlled or automatically-controlled. The tool used in this study is DCMT 11 insert type. The Taguchi method using the Orthogonal Array L9 design was used to compile the design of experiments with variations in depth of cut, coolant composition, and cooling fluid application methods. Each variable consists of three levels. Tool deterioration evaluated by observing it under an optic microscope from three sides of the tool. There are four levels of tool deterioration. The value of tool deterioration of each tool is the accumulation of each side view. ANOVA analysis found that depth of cut, cutting tool composition and method of applying coolant influence tool deterioration in percentage by 32.69%, 17.30 % and 12.82% respectively. Moreover, the minimum tool deterioration would be achieved when using the parameter combination of depth of cut of 1.6 mm; mixture composition of 3:7; and using the temperature-controlled MQL.
Analysis of Particulates and SO2 Removal from Coal Combustion Emissions Using Cyclone and Wet Scrubber With Textile Wastewater Feed
Authors: Huboyo Haryono S. , Sudarno Sudarno
Published: January 2021

Reuse of wastewater in the industry is mostly accomplished for watering plants. In a closed cycle, however, industrial wastewater can be returned through treatment to save water usage. This study aims to analyze textile wastewater's ability to be used as scrubbing liquid in the SO2 gas and particulate removal from coal combustion using a packed wet scrubber. Usually, the textile industry uses boiler fueled by coal and discharging base/alkaline wastewater. The method is carried out experimentally using a prototype device using a combination of cyclone and scrubber, with a source of coal combustion gas emissions. We did experiments using textile wastewater four times and two times using clean water as a control. We monitor the SO2, particulate emission in the gas stream, and pH, sulfate levels, and TSS levels in collected wastewater according to SNI. SO2 gas and particulates from coal combustion will be absorbed by the scrubber's wastewater spray so that SO2 will dissolve into sulfate, particulate matter into TSS. The study results using textile wastewater showed the removal efficiency of particulates on cyclone by 34-78%.  The removal efficiency of SO2 on wet scrubber was only 24.7%. There was an increase in TSS levels after passing through the scrubber by 46%. The rise in TSS and sulfate concentrations in the wastewater indicates the absorption of SO2 and particulates into wastewater. Based on this result, we can use textile wastewater for controlling the emission of SO2 and particulate from coal combustion by feeding it for the scrubber. However, the efficiency of this process is not optimal.
Die schrei(b)ende Kaste: Formen des Widerspruchs in Faustina Bamas Sangati
Authors: Rohrmoser Gernot
Published: January 2021

Der vorliegende Artikel beschäftigt sich mit dalitisch-feministischer Prosa. Anhand einer Analyse von Bamas Roman Sangati wird versucht, die in den Geschichten, Dialogen und Reflexionen transportierten und kodierten gesellschaftskritischen und dalit-feministischen Aspekte herauszuarbeiten. Darüber hinaus zeigt diese Auseinandersetzung auf, welche konkreten Formen des Widerspruchs die porträtierten Frauen entwickeln. Widerspruch manifestiert sich etwa im Durchbrechen und in der Infragestellung kultureller und sozialer Normen, dem Streben nach ökonomischer und sozialer Unabhängigkeit, der positiven Transformation diskriminierender Identitätszuschreibungen und letztendlich in der Sichtbarmachung einer authentischen (dalit-weiblichen) Stimme. Abschließend wird demonstriert, wie die herausgearbeiteten Aspekte in einem erweiterten gesellschaftlichen und wissenschaftlichen Rahmen Anknüpfungspunkte für politische und soziale Agitation liefern könnten.
Von der Modern Monetary Theory zur Forderung einer Jobgarantie
Authors: Höfgen Maurice , Ehnts Dirk
Published: January 2021

Analytischer Ausgangspunkt der MMT ist die Tatsache, dass der Staat das Währungsmonopol besitzt. Dieses ermöglicht ihm, die zur Erfüllung der staatlichen Aufgaben benötigten Ressourcen aus dem Privatsektor zu mobilisieren. Über die Höhe der Staatsausgaben und die Höhe der Steuern entscheidet der Staat über das Ausmaß der unfreiwilligen Arbeitslosigkeit. Daraus lässt sich die Forderung nach einer staatlichen universellen Jobgarantie herleiten. Die ökonomischen Implikationen der Jobgarantie betreffen unter anderem die Konjunktursteuerung, die Preisstabilität, die Kaufkraft der Währung sowie die Außenwirtschaft. Die sozial-gesellschaftlichen Implikationen beziehen sich auf die sozialen und psychologischen Kosten, die mit unfreiwilliger Arbeitslosigkeit assoziiert werden, die Wirkungen auf die Arbeitsbedingungen im privaten Arbeitsmarkt, auf die mögliche Korrektur der Kräfteverteilungen zwischen ArbeitgeberInnen und ArbeitnehmerInnen sowie auf demokratierelevante Aspekte.
La consolidación electoral del desequilibrio territorial e identitario en España (2008-2016). Réplica al artículo "Las huellas electorales del nacionalismo español"
Authors: Portillo Daniel Romero , Ruiz Jiménez Antonia María
Published: January 2021

El cambio del sistema de partidos y la profundización de éstos en la crisis territorial en el periodo posterior a la Gran Recesión de 2008 hacen interesante explorar también la polarización de la ciudadanía en el eje centro-periferia y la configuración del nuevo espacio electoral con respecto a este eje. El propósito de este artículo es conocer cómo se distribuyen las estructuras identitarias y a las preferencias sobre la organización territorial del Estado de las bases electorales de los partidos españoles bajo el nuevo contexto político-electoral. Para ello, se agregan los estudios post-electorales del CIS de 2008 a 2019, que se exploran de forma gráfica y mediante regresiones logísticas multinomiales. Nuestros hallazgos confirman que el deterioro apuntado por Jiménez y Navarro (2015) para las elecciones de 2011 no fue coyuntural, sino que se trata de una tendencia que se consolida desde 2015, estabilizándose hasta 2019.  Específicamente, se consolida la erosión del apoyo al Estado de las autonomías y aumenta de manera general el apoyo centralismo. Esta erosión no va acompañada, sin embargo, de una desvinculación generalizada de las identidades compartidas, aunque aumenten las identidades nacionales exclusivas. En cuanto al nuevo sistema de partidos, las bases electorales de los partidos se polarizan en gran medida en cuanto a sus preferencias sobre la organización territorial del Estado, pero no así con la identidad nacional.
Desde el Movimiento de Vida Independiente hasta la asistencia personal: los derechos de las personas con diversidad funcional
Authors: Lopéz Pérez Mercedes , Ruiz Seisdedos Susana
Published: January 2021

El objetivo de este artículo es realizar un estudio teórico del primer movimiento social protagonizado por las propias personas con diversidad funcional, el denominado Movimiento de Vida Independiente (MVI), así como uno de los recursos que originó, la denominada, asistencia personal (AP). Este estudio pretende profundizar en el conocimiento de este movimiento, su origen, desarrollo, su filosofía de vida y en las demandas y reivindicaciones del mismo a nivel mundial, en primer lugar, y en España, en los últimos años. Entre dichas demandas se encuentra el empoderamiento de las personas con diversidad funcional a través del recurso, poco conocido en nuestro país, de la asistencia personal, por lo que se analizarán sus funciones, tareas, requisitos y beneficiarios. Debido a que actualmente existe un escaso desarrollo académico de esta temática en nuestro país, pero en lo últimos años ha habido un creciente interés en esta figura laboral por parte de las propias personas con diversidad funcional, por las organizaciones del sector y por las administraciones públicas, se hará una revisión bibliográfica y documental exhaustiva.
Evaluación del riesgo toxicológico por exposición a plomo y cadmio en suelos de los alrededores del Parque Industrial Infantas, Los Olivos
Authors: Olórtegui Denisse , Ynocente Christopher , García Mesías , Marín Gloria
Published: January 2021

El objetivo del presente estudio fue evaluar el riesgo toxicológico por exposición a suelos con presencia de plomo y cadmio en zonas aledañas al Parque Industrial Infantas en Los Olivos – Lima (2018). Se tomaron 40 muestras del suelo, 20 muestras en la urbanización Carabayllo y 20 muestras en la urbanización Villa del Norte. Se obtuvo que la concentración de Pb y Cd en la Urb. Carabayllo tuvo una media de 66,97 mg/kg y 0,86 mg/kg; para la Urb. Villa del Norte es de 51,43 mg/kg y 0,73 mg/kg respectivamente. Las concentraciones obtenidas cumplen con el Estándar de Calidad Ambiental (ECA) del Ministerio del Ambiente de Perú. Se estimó la Dosis de Exposición (DE) en la urbanización Carabayllo, para adultos, se obtuvo una DEPb= 0,000143 mg/kg/día y DECd= 0,000002 mg/kg/día; y para niños, una DEPb= 0,002494 mg/kg/día y DECd= 0,000032 mg/kg/día. En la urbanización Villa del Norte, para adultos, se obtuvo una DEPb= 0,000109 mg/kg/día y DECd= 0,000002 mg/kg/día; y para niños, una DEPb= 0,001916 mg/kg/día y DECd= 0,000027 mg/kg/día. Luego del cálculo de la DE, se procedió con el cálculo del Índice de Peligrosidad. Se obtuvo un índice por debajo del 1 (IP<1) por lo que el riesgo toxicológico por exposición al suelo fue aceptable para la población.
Economía solidaria
Authors: Quispe Andía Raquel Giulianna
Published: January 2021

La economía solidaria, o también llamada social, es una propuesta que vienen impulsando economistas y filósofos desde Europa y que ha tenido gran eco en América latina. ¿Es posible insertar el componente solidario en la economía? Es la pregunta fundamental que los diversos autores buscan dar respuesta a partir de una propuesta de economía alternativa con mayor equidad y valoración del trabajo del hombre, ante la crisis del sistema económico actual. En este artículo, se propone realizar una revisión del concepto de economía solidaria, y las propuestas de los principales autores que pretenden construir una alternativa desde diferentes ángulos. Para contrastar el planteamiento de esta propuesta se citarán ejemplos en el Perú de cómo ha sido puesta en práctica y cuáles son los primeros resultados.
Autoestima y desempeño laboral de las enfermeras del Hospital Daniel Alcides Carrión-Callao
Authors: Huaman Gutierrez Zoraida Judith , Tarazona Miranda Victor , Olivares Taipe Paulo César
Published: January 2021

El objetivo fue determinar la relación entre autoestima y desempeño laboral de las enfermeras del\Hospital Daniel Alcides Carrión". El método corresponde a un estudio básico, de nivel correlacional, enfoque cuantitativo, diseño no experimental y transversal. La población se conformó por 289 enfermeras, habiendose elegido a 165 del total de forma no probabilística. La recolección de datos se realizó a través de dos instrumentos con un valor de conabilidad de 0,922 y 0,965 respectivamente. Para el análisis bivariado se utilizó la prueba de Chi-Cuadrado aplicándose el análisis de correspondencia simple. Los resultados señalaron que existe relación significativa entre autoestima y desempeño laboral en las enfermeras del hospital Daniel Alcides Carrión. (χ2 = 33,898; p < 0,01), también se demostró que existe relación signicativa entre autoestima y la competencia cognitiva (χ2 = 24,883; p < 0,01), igualmente entre autoestima y las competencias actitudinales/sociales (χ2 = 25,739; p < 0,01) y entre la autoestima y la competencia técnica (χ2 = 18,092; p < 0,05). La investigación concluye que un buen nivel de autoestima mejora signicativamente el desempeño laboral en las enfermeras del hospital Daniel Alcides Carrión.
Determinación del curso temporal de fluoxetina y norfluoxetina en perros Pastor Alemán y Akita Inu
Authors: Tapia Araya Christian Marcelo , Tapia Tapia Elizabeth Margarita , Millahueque Salas Nicol Yaquelin , Ríos Phillips Carolina Lucía , Chávez Contreras Gonzalo Alfredo
Published: January 2021

Se evaluó la farmacocinética de la fluoxetina en dos razas de perros filogenéticamente distantes. Para lograrlo, se puso a punto y validó el método de cuantificación donde se calculó el promedio, la desviación estándar y el coeficiente de variación (CV) para cada punto. Los valores del CV fueron del orden del 2%. El límite de detección fue de 3.36 ng/ml y correspondió a tres veces la señal ruido de la muestra blanco. El límite de cuantificación (LOQ) fue de 10.53 ng/ml. El análisis cromatográfico indicó que a las dos horas de la administración se alcanzaron las máximas concentraciones de fluoxetina (Akika Inu: 41.8±0.6 ng/ml; Pastor Alemán: 45.3±1.4.0 ng/ml), mientras que las concentraciones mínimas se alcanzaron a las 80 horas (Akika Inu: 3.9±0.1 ng/ml; Pastor Alemán: 3.9±0.1 ng/ml). Solo se encontró diferencia significativa entre razas en los valores alcanzados a las 2 h pos-administración (p<0.05). Se puede presumir que, debido a las diferencias en la curva temporal, el manejo farmacológico podría ser diferente entre razas filogenéticamente diferentes.
Serotipificación de Escherichia coli aislados a partir de superficies vivas e inertes en un mercado de carne de pollo (Lima, Perú)
Authors: Morales-Cauti Siever , Salazar V. Elinor , Ampuero-Riega Lizette , Navarro O. Armando
Published: January 2021

El presente estudio tuvo por objetivo identificar y serotipificar cepas aisladas de manos de vendedores, tabla de picar y mesas de expendio de 50 puestos de venta de carne de pollo de un mercado de abasto del distrito de San Juan de Miraflores, Lima, Perú. La toma de muestra fue realizada con hisopos estériles sobre las superficies indicadas. En el transporte de las muestras se utilizó el medio Stuard, el enriquecimiento se realizó en caldo de tripticasa de soya y el aislamiento se desarrolló en agar McConkey. Las colonias lactosas positivas compatibles con E. coli se identificaron mediante pruebas bioquímicas estándar. La serotipificación se realizó utilizando el método descrito por Kauffman para detectar el antígeno somático (O) y flagelar (H) con antisueros específicos SERUNAM. El 42% (63/150) de las muestras fueron identificadas como E. coli, lográndose serotipificar 58 cepas viables que pertenecen a 40 serotipos, donde el O6H10 fue el de mayor frecuencia (10.3%, 6/58).
¿Tomar lotes para vivir o para vender? Tráfico de tierras y práctica clientelar en la periferia urbana
Authors: Pimentel Sánchez Nekson
Published: January 2021

Este artículo aborda las relaciones clientelares y su relación con el tráfico de terrenos en las periferias de la urbe limeña. ¿Cuáles son las características y estructura del clientelismo? ¿Cuáles son las formas, agentes y mecanismos del tráfico de terrenos? Estas preguntas permitirán dar cuenta sobre la producción de la ciudad atrapada en una serie de transacciones que puede involucrar a diversos agentes y niveles de especialización en la toma de tierras y la construcción de asentamientos urbanos en la periferia de Lima Metropolitana.
Después de la llegada: Realidades de la migración venezolana
Authors: Portocarrero Corzo Adriana
Published: January 2021

El presente libro, “Después de la llegada: realidades de la migración venezolana”, surge como resultado de un esfuerzo articulado e interdisciplinario, impulsado por el Instituto de Democracia y Derechos Humanos de la Pontificia Universidad Católica del Perú (Idehpucp) y en apoyo de otros actores.
Las comunidades campesinas y nativas en el Perú hoy
Authors: Infante Esteban Kyara
Published: January 2021

Los autores Jaime Urrutia, María Isabel Remy y María Luisa Burneo en el libro Comunidades campesinas y nativas en el contexto neoliberal peruano, aterrizan parte de esta investigación en una lectura del Censo Nacional Agrario 2012 y las hojas complementarias donde hacen una análisis cuyo objetivo principal es mostrar las tendencias generales sobre diversos aspectos presentes en las comunidades campesinas y nativas y de esta manera dar cuenta de los problemas actuales a los que estas se enfrentan dentro del contexto neoliberal actual.
Internet dan Metamorfosa Generasi Digital: Analisa Perbandingan Perilaku Penyebarluasan Berita Hoax Lintas Generasi
Authors: Maulidina Rizka , Ridho Kholis
Published: January 2021

Generasi lanjutan dari immigrant digital adalah metamorphosis digital, yaitu bentuk perubahan yang biasanya dikenal dalam ilmu biologi untuk menunjukkan perubahan wujud dari kepompong menjadi kupu-kupu dan atau hewan serupa lainnya. Peneliti mengajukan pembuktian kemampuan responden mengenali berita benar dan palsu di setiap generasi. Benarkah generasi yang lebih senior lebih mampu mengenali berita palsu dibanding generasi milenial? Apakah penyebarluasan berita palsu kepada yang lain lebih banyak dilakukan generasi milenial dan sebaliknya? Populasi dalam riset ini adalah seluruh civitas akademik Fakultas Ilmu Dakwah dan Ilmu Komunikasi UIN Syarif Hidayatullah Jakarta yang terdiri dari seluruh dosen dan mahasiswa Komunikasi Penyiaran Islam dan Jurnalistik angkatan 2015. Hasilnya, konsumsi dan penyebarluasan berita hoax dapat dilakukan oleh semua generasi. Karena itu riset ini menolak kategori immigrant digital berdasarkan kategori usia atau waktu kelahiran, karena SDM digital atau metamorphosis human digital lebih ditentukan oleh kualitas yang bersangkutan dalam mengomsumsi berita dan informasi, penguasaan teknologi informasi, dan keluasan wawasan serta pengetahuannya.
Improving Care and Outcomes for Pediatric Musculoskeletal Infections
Authors: Hester Gabrielle Z. , Nickel Amanda J. , Watson David , Swanson Gloria , Laine Jennifer C. , Bergmann Kelly R.
Published: January 2021

BACKGROUND:

Pediatric musculoskeletal infection (MSKI) is a common cause of hospitalization with associated morbidity. To improve the care of pediatric MSKI, our objectives were to achieve 3 specific aims within 24 months of our quality improvement (QI) interventions: (1) 50% reduction in peripherally inserted central catheter (PICC) use, (2) 25% reduction in sedations per patient, and (3) 50% reduction in empirical vancomycin administration.

METHODS:

We implemented 4 prospective QI interventions at our tertiary children’s hospital: (1) provider education, (2) centralization of admission location, (3) coordination of radiology-orthopedic communication, and (4) implementation of an MSKI infection algorithm and order set. We included patients 6 months to 18 years of age with acute osteomyelitis, septic arthritis, or pyomyositis and excluded patients with complex chronic conditions or ICU admission. We used statistical process control charts to analyze outcomes over 2 general periods: baseline (January 2015–October 17, 2016) and implementation (October 18, 2016–April 2019).

RESULTS:

In total, 224 patients were included. The mean age was 6.1 years, and there were no substantive demographic or clinical differences between baseline and implementation groups. There was an 81% relative reduction in PICC use (centerline shift 54%–11%; 95% confidence interval 70–92) and 33% relative reduction in sedations per patient (centerline shift 1.8–1.2; 95% confidence interval 21–46). Empirical vancomycin use did not change (centerline 20%).

CONCLUSIONS:

Our multidisciplinary MSKI QI interventions were associated with a significant decrease in the use of PICCs and sedations per patient but not empirical vancomycin administration.
Suplementación de vacas lecheras en producción con un complejo de vitaminas B recubierto
Authors: Beita-Carvajal Karen Gabriela , Elizondo-Salazar Jorge Alberto
Published: January 2021

Introducción. Los requerimientos de vitaminas B en rumiantes son satisfechos por su capacidad de síntesis a nivel ruminal. El mejoramiento genético, los avances en nutrición animal y los altos niveles de producción actuales, puede hacer que los animales no estén llenando sus requerimientos. Objetivo. Evaluar el efecto que tiene el uso de un complejo de vitaminas del grupo B sobre la producción láctea y el metabolismo de vacas lecheras en pastoreo. Materiales y métodos. Durante el segundo semestre del 2017, se utilizaron treinta vacas Jersey divididas en dos grupos que se mantuvieron durante dos periodos experimentales de 30 días. Durante el primer periodo de un mes, los animales del primer grupo recibieron 3,0 g diarios de un complejo de vitaminas B, mientras que los animales del otro grupo recibieron un placebo y para el periodo 2 se intercambiaron los tratamientos. Se midió la producción y composición láctea durante todo el periodo. Se midieron variables químicas como glucosa, betahidroxibutirato, aspartato amino transferasa, nitrógeno ureico y albúmina en sangre. Resultados. No se presentaron diferencias significativas (p>0,05) con respecto a la producción láctea. En el periodo 1, el grupo suplementado produjo 15,8 l por día; mientras que el grupo control produjo 16,1 l. Las concentraciones de grasa, proteína y lactosa en el primer periodo fueron de 5,0, 3,5 y 4,4 %, respectivamente. En el periodo 2, la producción láctea fue de 14,1 y 13,7 l para el grupo suplementado y no suplementado, respectivamente. En ningún periodo se observaron diferencias significativas (p>0,05) para los parámetros de química sanguínea analizados. La concentración de glucosa fue superior a 40 mg dl-1 y la concentración de betahidroxibutirato fue superior a 2,0 mmol l-1. Conclusión. Suplementar vacas Jersey con un complejo de vitaminas B de sobrepaso no mostró ventaja alguna con respecto a las variables productivas evaluadas.
Visibilizar los proyectos de las Sedes Regionales Universitarias
Authors: Barahona Barahona Blanca Azucena
Published: January 2021

El presente artículo reside en la investigación que se realizó en las Sedes Regionales de Educación Superior estatales ubicadas en Guanacaste. Se efectuó un análisis de los sistemas institucionales que utilizan las universidades en la formulación de proyectos de investigación y extensión. Se determinó que, aunque los procedimientos conllevan a un mismo fin, los sistemas de la Universidad de Costa Rica, Universidad Nacional y la Universidad Estatal a Distancia son muy diferentes, cuyo resultado no permite la compatibilidad tecnológica ni observar los proyectos que ejecutan las universidades públicas que las vinculan con la sociedad costarricense.  Como corolario de la investigación, se propone un sistema con miras a integrar las plataformas tecnológicas y visibilizar los proyectos, en beneficio de la comunidad universitaria regional y nacional. Por lo cual es fundamental la coordinación de las direcciones de investigación y extensión de las Sedes Regionales con las Bibliotecas, para aprovechar sus capacidades en el tratamiento y diseminación de la información.