bluuebunny/crossref_metadata_2025 huggingface dataset:
Plant Molecular Biology Databases
Authors: Awan Zubir
Published: September 2019

Many of plant biological database comprises data from study fields including metabolomics, proteomics, genomics, microarray gene expression, and phylogenetic. Information in biological databases involves the role of genes, composition, chromosomal location, clinical impacts of mutations, and similarity of biological sequences and characteristics. We are here targeting to review and rank some of the plant databases according to their use and feature. Hoping that scientists could use this study to pick, combine and correlate distinct databases, based on their study needs and objective specifications.
Economic Burden of Contraception Management in Spain
Authors: Parra Ribes Inmaculada , Rascón Poza Juan José , Pérez Campos Ezequiel , Bugella Yudice Ignacio , Rodríguez Domingo Maria Jesús
Published: September 2019

Background: A wide variety of contraceptive methods are available, some of them reimbursed by the Spanish National Health System (SNHS). However, the number of unintended pregnancies (UP) is still significant, leading to a high economic burden, mainly derived from non-adherence to and the incorrect use of contraceptive methods.

Objectives: This study aims to estimate the economic burden associated with reversible contraception management in Spain, from the perspectives of both the SNHS and women, over a 5-year period.

Methods: A survey was performed to identify contraception management in Spain based on the experience of a panel of six expert gynecologists. An economic model was conducted to quantify the current burden of contraception according to healthcare resources use over 5 years. The costs included in the analysis were diagnostic tests, initial and follow-up consultations, methods acquisition costs, and UP derived from therapy failure.

Results: Reversible contraception costs in Spain amount to €12.5 billion over a 5–year period. Condoms and combined oral contraceptives (COC) account for 86.8% of the total cost and the other methods only 13.2%. There are differences in contraceptive use according to women’s age. Short-acting reversible contraceptives (SARC) such as COC, condom and vaginal ring, are most commonly used by younger women. However, SARC are correlated with the highest failure rate, resulting in over €7.2 billion cost, explained by the high number of UP. Long-acting reversible contraceptives (LARC), such as the levonorgestrel-releasing intrauterine system (LNG-IUS20), implant and copper intrauterine devices (IUD), are selected by women over 35 years of age due to user-independent compliance. SARC methods result in a higher cost per woman over 5 years: vaginal ring €2427.8, patch €2402.6, condom €2060.1 and COC €1895.1; while LARC methods are the most economic option per women: LNG-IUS20 €630.4, copper IUD €658.2, LNG-IUS12 €703.8, intramuscular injectable €907.8 and implant €940.5.

Conclusions: LARC methods result in lower costs compared with SARC options from the perspectives of the SNHS and women, explained by user-independent compliance, preventing a significant number of UP and its elevated economic burden. An increased LARC methods use could avoid UP events, leading to significant cost-savings for the SNHS.
Fluorescent phosphorus dendrimers excited by two photons: synthesis, two-photon absorption properties and biological uses
Authors: Caminade Anne-Marie , Zibarov Artem , Cueto Diaz Eduardo , Hameau Aurélien , Klausen Maxime , Moineau-Chane Ching Kathleen , Majoral Jean-Pierre , Verlhac Jean-Baptiste , Mongin Olivier , Blanchard-Desce Mireille
Published: September 2019

Different types of two-photon absorbing (TPA) fluorophores have been synthesized and specifically functionalized to be incorporated in the structure of phosphorus dendrimers (highly branched macromolecules). The TPA fluorophores were included in the periphery as terminal functions, in the core, or in the branches of the dendrimer structures, respectively. Also the functionalization in two compartments (core and surface, or branches and surface) was achieved. The consequences of the location of the fluorophores on the fluorescence and TPA properties have been studied. Several of these TPA fluorescent dendrimers have water-solubilizing functions as terminal groups, and fluorophores at the core or in the branches. They have been used as fluorescent tools in biology for different purposes, such as tracers for imaging blood vessels of living animals, for determining the phenotype of cells, for deciphering the mechanism of action of anticancer compounds, and for safer photodynamic therapy.
Antibiotic resistance and biofilm formation in children with Enteropathogenic Escherichia coli (EPEC) in Brazilian Amazon
Authors: Rodrigues Renata Santos , Lima Nucia Cristiane da Silva , Taborda Roger Lafontaine Mesquita , Esquerdo Rosimar Pires , Gama Antonieta Rodrigues , Nogueira Paulo Afonso , Orlandi Patricia Puccinelli , Matos Najla Benevides
Published: September 2019

Introduction: Enteropathogenic Escherichia coli is an important causative agent of diarrhea in both developed and developing countries.

Methodology: We assessed the antibiotic resistance profile and the ability of 71 Enteropathogenic Escherichia coli (EPEC) isolates from children in the age group 6 years, or younger, to form biofilm. These children were hospitalized in Cosme and Damião Children Hospital in Porto Velho, Western Brazilian Amazon, between 2010 and 2012, with clinical symptoms of acute gastroenteritis.

Results: The highest frequency of atypical EPEC (aEPEC) isolates reached 83.1% (59/71). Most EPEC isolates presented Localized Adherence Like (LAL) pattern in HEp-2 cells (57.7% - 41/71). Biofilm production was observed in 33.8% (24/71) of EPEC isolates, and it means statistically significant association with shf gene (p = 0.0254). The highest antimicrobial resistance rates and a large number of multiresistant isolates 67.6% (48/71), regarded cefuroxime (CXM), ampicillin (AMP), trimethoprim-sulfamethoxazole (SXT) and tetracycline (TET), respectively, mainly in typical EPEC (tEPEC). Furthermore, 96% (68/71) of EPEC isolates in the present study were resistant to at least one antibiotic, whereas only 3 isolates were sensitive to all the tested drugs.

Conclusion: Based on our findings, there was increased aEPEC identification. EPEC isolates showed high resistance rate; most strains showed multiresistance; thus, they work as warning about the continuous need of surveillance towards antimicrobial use. Besides, the ability of forming biofilm was evidenced by the EPEC isolates. This outcome is worrisome, since it is a natural resistance mechanism of bacteria.
A multicenter study of β-lactamase-producing Klebsiella pneumoniae isolated from university teaching hospitals of Urmia, Iran
Authors: Darabi Narges , Motazakker Morteza , Khalkhali Hamid Reza , Yousefi Saber
Published: September 2019

Introduction: Klebsiella pneumoniae is an opportunistic pathogen accounting for 5-7% of hospital acquired infections. The emergence of carbapenem-resistant Klebsiella pneumoniae has been increasing rapidly over recent years causing many therapeutic problems worldwide. This study aimed to research the antimicrobial resistance profile, detect β-lactamase genes among clinical isolates of K. pneumoniae, and determine their clonal relatedness.

Methodology: All Klebsiella pneumoniae isolates were obtained from teaching hospitals in Urmia, Iran. Antimicrobial susceptibility testing was done by the disk diffusion method. Furthermore, minimum inhibitory concentrations of imipenem were determined by applying Etest strips. Screening of β-lactamase-producing isolates was performed by the combined disk method and modified Hodge test. The detection of β-lactamase genes was conducted by polymerase chain reaction (PCR), and isolates’ clonal relatedness was evaluated by random amplified polymorphic DNA (RAPD)-PCR.

Results: Overall, 45 out of 182 (24.7%) K. pneumoniae isolates were non-susceptible to imipenem. The combined disk method and modified Hodge test revealed that 93.3% and 71.1% of the imipenem non-susceptible isolates were β-lactamase producers, respectively. The presence of blaVIM, blaNDM, blaKPC, and blaIMP genes was confirmed in 48.9%, 15.6%, 11.1%, and 6.7% of the β-lactamase-producing isolates, respectively. RAPD-PCR revealed that 73% of these isolates were classified into six different clusters.

Conclusions: A relatively high prevalence of β-lactamase genes was seen among multidrug-resistant isolates of K. pneumoniae. Most patients infected with β-lactamase-producing isolates had a history of long-term hospitalization and nosocomial infections. The predominance of β-lactamase genes in intensive care unit and internal units alarm clinicians to the growth of hospitalization and mortality rates.
Dépistage du cancer colorectal en officine en Corse : un appui à la prévention en médecine générale
Authors: Le Duff Franck , Grisoni Antoine , Filippi Christian , Orabona Joseph
Published: September 2019

Le cancer colorectal (CCR) touche chaque année environ 43 000 personnes en France et est responsable de près 18 000 décès par an. Le Programme national de dépistage organisé contribue à sa détection précoce. La mise à disposition du kit se fait auprès du médecin traitant ou, à défaut, auprès du centre régional en charge de la personne invitée. Bien souvent, la démarche consistant à se rendre chez son médecin traitant pour récupérer le test n’est pas faite et la participation au dépistage organisé en pâtit. Notre projet vise à évaluer l’impact de la mise à disposition de ce test dans les pharmacies sur le dépistage du cancer colorectal en Corse. L’article décrit la méthode employée pour mobiliser les pharmaciens des officines du territoire et les fournir en kits de dépistage ainsi que le suivi des personnes qui ont participé au test. Les résultats présentés mettent en évidence un impact très positif de l’expérimentation, avec une progression du taux de réalisation à 36 % sur la période.
Analysing WhatsApp and Instagram as Blended Learning Tools
Authors: Andujar Alberto
Published: September 2019

This chapter explores, from a theoretical point of view, the literature investigating the use of WhatsApp and Instagram applications to foster language learning as well as the outcomes of the studies carried out in these two fields. The possibilities of these two apps to develop blended learning environments are also regarded. The theoretical frameworks in the existing literature for the possible implementation of these social networking tools in classroom contexts are considered. Findings indicate a growing number of studies making use of the WhatsApp application to develop either blended learning models or online tasks in foreign language courses while the research exploring the use of Instagram for language development remains very scarce.
Effect of Nanocarbons Additions on the Microstructures and Properties of Copper Matrix Composite by Spray Drying Process
Authors: Ji Pu Guang , Qi Dan Dan , Yin Fu Xing , Wang Gong Kai , Bobrynina Elizaveta , Tolochko Oleg
Published: September 2019

Novel copper-nanocarbons – Cu-fullerene soot/reduced graphene oxide composites with 0-5 wt.% carbon additions were fabricated by spray drying method and hot pressing procedure. In order to obtain the homogeneity of composites, the spray drying integrating with shear mixing was adopted. The microstructure and properties of the composite materials were investigated and compared to Cu–graphite composite, which was prepared under the standard technology. The interface, depending on the nanocarbons addition, prevents copper aggregation, and inhibits the copper grain growth. The compact composites hardness was significantly higher as compared with Cu-CNTs and Cu-Graphite composites of the same carbon concentration with small reduction of the thermal conductivity.
Manufacture of a High-Pressure Centrifugal Fan Made of 316l by the Method of High-Speed Direct Laser Deposition
Authors: Topalov I.K. , Golovin Pavel A. , Lanin Alexander A. , Gerasimov Nikolay Ivanovich
Published: September 2019

The article discusses the manufacturing technology of the impeller of a high-pressure centrifugal fan using high-speed direct laser spraying. The outer diameter of the part is 1200 mm, the total weight is 100 kg. The material used is metal powder stainless steel 316L. Features of the manufactured products were researched, including possible thermal deformations and methods for dealing with them.
Aspect-Independent Siliconglass Etching by Bosch Method
Authors: Alekseev R.A. , Alieva Aleksandra I. , Kucal Ewelina
Published: September 2019

The purpose of this work was to study and carry out glass etching of monocrystalline silicon using the Bosch method, acquaintance with the conditions of aspect-independent etching. The Bosch process was conducted using sulfur hexafluorideSF6 and perfluorocyclobutaneC4F8on OxfordInstrumentsPlasmaPro®Estrelas100. It was found that in order to level the problems that arise, it is necessary to vary the temporal relations of etching and passivation stages.
Study of Micro-Hardness of Steel Surfaces after their Friction in the Medium of Plastic Lubricating Material Used in the Units and Mechanisms of Equipment of Oil and Gas and Shipbuilding Industry
Authors: Steshenkov Alexey Leonidovich , Chulkin Sergey Georgievich , Alkhimenko Aleksey Aleksandrovich , Shaitor Sergey D. , Bogatyrev Konstantin Dmitrievich , Tarasova Viktoriya Alexandrovna
Published: September 2019

The paper presents studies of the Vickers hardness of various areas of steel friction surfaces, on which normal and adhesive types of wear were observed after the process of friction in the environment of the lubricant of various grades. Implemented a comparison of the friction surface hardness with the original surface. It is shown that the hardness varies in the process of friction and has different values ​​depending on the lubricating medium and the type of wear.
Studies of Tribological and Corrosion Properties of Coatings Based on Iron for Light Alloy Drill Pipes of Aluminium Alloys
Authors: Shemyakinskiy Boris Aleksandrovich , Skotnikova Margarita Alexandrovna , Wang Zi Xi , Alkhimenko Aleksey Aleksandrovich
Published: September 2019

The paper presents the results of tribotechnical studies of anti-wear properties of iron-based coatings for light-alloy drill pipes made of aluminum alloys. The description of the tribotechnical stand simulating real processes of drilling in a wide range of conditions is given. Also, the analysis of corrosion resistance of coatings by electrochemical analysis was carried out. The results showed that there is a potential for the use of this type of coating.
Application of Innovational Sc-Containing Alloys in Shipbuilding
Authors: Gogolukhina Maria , Mamedova Leyla , Scholtz Olga
Published: September 2019

Modern shipbuilding yards apply traditional aluminum alloys in production of high-speed vessels, ships with dynamic principles of support, other small vessels and vessel constructions. These alloys provide the low weight for the construction, but have definite disadvantages, which could be improved by application of the new generation Al-Sc-alloy with low concentration of scandium. The developed technology allows to increase durability and to improve other mechanical characteristics, decrease the vessels’ weight, decrease operational costs, increase the operational lifecycle of the production, as well as to achieve some indirect effects. The feasibility study was held to assess the economic effect of applying the new generation Al-Sc-alloy in shipbuilding, which proves its advantages comparing to traditionally used Al-alloys.
Smart technology for healthcare: Exploring the antecedents of adoption intention of healthcare wearable technology
Authors: Chau Ka Yin , Lam Michael Huen Sum , Cheung Man Lai , Tso Ejoe Kar Ho , Flint Stuart W. , Broom David R. , Tse Gary , Lee Ka Yiu
Published: September 2019

Technological advancement and personalized health information has led to an increase in people using and responding to wearable technology in the last decade. These changes are often perceived to be beneficial, providing greater information and insights about health for users, organizations and healthcare and government. However, to date, understanding the antecedents of its adoption is limited. Seeking to address this gap, this cross-sectional study examined what factors influence users’ adoption intention of healthcare wearable technology. We used self-administrated online survey to explore adoption intentions of healthcare wearable devices in 171 adults residing in Hong Kong. We analyzed the data by Partial least squares – structural equation modelling (PLS-SEM). The results reveal that perceived convenience and perceived irreplaceability are key predictors of perceived usefulness, which in turn strengthens users’ adoption intention. Additionally, the results also reveal that health belief is one of the key predictors of adoption intention. This paper contributes to the extant literature by providing understanding of how to strengthen users’ intention to adopt healthcare wearable technology. This includes the strengthening of perceived convenience and perceived irreplaceability to enhance the perceived usefulness, incorporating the extensive communication in the area of healthcare messages, which is useful in strengthening consumers’ adoption intention in healthcare wearable technology.
Efficiency and reporting confidence analysis of sequential dual-energy subtraction for thoracic x-ray examinations
Authors: Gezer Mehmet Can , Algin Oktay , Durmaz Aytac , Arslan Halil
Published: September 2019

Rationale and objectives: We aimed to report and compare accuracy, reproducibility, and reporting confidence between thoracic dual-energy subtraction (DES) and routine posterior–anterior chest radiography (PA-CR) techniques. Materials (patients) and methods: We obtained DES (D1–D4) images from 96 patients using DES and a high-resolution dynamic flat-panel detector in combination. We compared the DES images of these patients with their PA-CR images. The maximum time interval between performing DES and PA-CR was nine weeks. Two radiologists evaluated abnormal findings on DES and PA-CR images using a three-point scale, and reporting confidence was scored using a four-point scale. The intra- and interobserver agreement values of the scores were analyzed. Further, the radiation exposure doses during PA-CR and DES acquisitions were calculated. Results: The intra- and interobserver agreement values of PA-CR and DES images were good. The reporting confidence scores for DES were generally higher than those for PA-CR. Between bone-subtracted (D3) and soft-tissue-subtracted (D4) images, the former was more successful and useful in the evaluation of bone structures, whereas the latter was better in the evaluation of consolidation and/or solitary nodules. Conclusions: DES has the potential to improve the accuracy, reproducibility, and reporting confidence of thoracic radiography. It also has the potential to provide a better diagnosis of chest pathologies using relatively low dose radiation.
Addressing Antibiotic Hip Spacer Instability via Hybrid Screw-cement Fixation of a Constrained Liner and Cement-rebar Interface Techniques: A Technical Narrative
Authors: Patel Jay N. , Pizzo Richard A. , Yoon Richard S. , Liporace Frank A.
Published: September 2019

Prosthetic joint infection is a challenging and devastating complication after total hip arthroplasty. The benchmark for treatment remains two-stage revision arthroplasty, in which an antibiotic-impregnated spacer is used to eradicate the infection. Although several types of spacer constructs have been described, they have historically been associated with high rates of mechanical complications, namely, dislocation, spacer fracture, and periprosthetic femur fracture. Spacer dislocation is the most common, with reported rates as high as 41%. Here, the authors present a surgical technique to improve the mechanical stability of an articulating hip spacer via a hybrid screw-cement fixation technique that allows for joint motion and weight bearing during the treatment period while minimizing the risk of mechanical failure. An additional technique is described to address acetabular bone loss, which has been associated with a higher spacer dislocation rate, through a cement-rebar interface construct.
Examination of Attitudes of Sports Science Faculty Students about Energy Drinks, Sports Drinks and Ergogenic Substances
Authors: Dolek Burcu Ertas , Bosi Tulay Bagci
Published: September 2019

Consumption of beverages is not considered adequate by athletes and coaches. The preliminary knowledge of those who are going to study in Sports Sciences Faculties will be very important. All participants were 1st year students. In the study, participants were asked to assess their socio-demographic characteristics and health behaviors, sport habbits, to determine energy drinks (ED), sports drinks (SD) and ergogenic substances (ES) patterns and frequency and consumption purposes, relationship between consumption status. Use a data collection form was prepared to determine the presence or absence of relevant proposals. Total of 101 participants (55 males, 19.2±1.5; 46 females, 19.0±1.2 years of age), participated in the survey to examine the attitudes of ED, SD and ES.  The data were evaluated in the SPSS 21.0. The categorical variablesin the questionnaire were reported as number, percentage, mean and standard deviation. A "chi-square test" and One way ANOVA tests was used. Statistical significance level was accepted as p <0,05. 52.5% of the students stated that energy drinks were beneficial, 57.4% said sports drinks were beneficial and 61.4% of the participants said that they did not have an idea about "ergogenic substances". The prevalence of ED usage was 40.0% for males and 19.5% for females (p: 0.027). While 45.4% of the males are using the SDs, this rate was found to be 13.0% in females (p<0.001). Regarding the use of ED, SD and ES, the young population and especially the sports educators in the future should be informed for the public health. As a result of this study, we would like to draw attention to the importance of education for pre-university youth. In recent years, it is important to make new educational arrangements for the developing and changing consumption habits of young people.
The Relationship Between the Cultural Structure of Schools and the Political Behaviors of Teachers
Authors: Iseri Emel Tuzel
Published: September 2019

This study aimed to determine the relationship between the cultural structure of schools and the political behaviors that teachers exhibit within the school. The study group of this study that employed a relational screening model consisted of 489 teachers working in pre-school, elementary, and middle schools in Tokat city center in 2019. The data were collected using the School Culture Scale developed by Terzi (2005) and the Political Behaviors Scale developed by İslamoğlu and Börü (2007). The study found that teachers mostly perceived the cultural structure of their school with duty culture, which was followed by support culture and success culture. According to the perceptions of teachers, the least perceived culture in their school was the bureaucratic culture. The study concluded that as the level of teachers’ perception of support, success and duty culture in their schools increased, their level of exhibiting all political behaviors including those in horizontal and vertical hierarchy decreased, whereas the bureaucratic culture that they perceived in their school increased the horizontal, vertical, and all political behaviors.
Leren exonereren: een aantal gezichtspunten ten aanzien van het contractueel reguleren van aansprakelijkheid
Authors: van Wechem T.H.M.
Published: September 2019

Leren exonereren: een aantal gezichtspunten ten aanzien van het contractueel reguleren van aansprakelijkheid

In deze bijdrage wordt de rol die exoneraties in b2b-verhoudingen spelen besproken en formuleert de auteur regels die bij het opstellen van een goede exoneratiebepaling van nut kunnen zijn. De auteur wijst op het belang van het juridisch (logistiek) kwalificeren van de overeenkomst, de vraag of de schadeplicht voortvloeit uit een temporeel of kwalitatief ten achter blijven en op de uitleg van exoneraties. Onderzocht wordt ook of toetsing van het beding aan de beperkende werking van de redelijkheid veel verschilt van de norm ‘onredelijk bezwarend’ uit artikel 6:233 sub a Burgerlijk Wetboek en de omstandigheden die in de rechtspraak een rol spelen bij de beantwoording van de vraag of een exoneratie terzijde moet worden gesteld.
De ‘prognose-torpedo’: een effectief verweermiddel tegen vorderingen in kort geding
Authors: Kolenbrander J.H.
Published: September 2019

De ‘prognose-torpedo’: een effectief verweermiddel tegen vorderingen in kort geding

Een beroep op dwaling vanwege een ondeugdelijke prognose kan in kort geding een effectief verweermiddel zijn van een franchisenemer om de vordering van een franchisegever af te laten wijzen door de rechter.
Mitologia podatkowa: od czego zależy w rzeczywistości
wzrost albo spadek dochodów budżetowych?
Authors: Modzelewski Witold , Lipnicki Alan
Published: September 2019

Luka w podatku od towarów i usług, zwłaszcza do 2015 r., stanowiła w Polsce ogromny problem w zakresie poborów
podatkowych, bo pomniejszała krajowe wpływy z tego tytułu o około 3% PKB w ujęciu rocznym. Podjęte
działania uszczelniające przyniosły znaczącą poprawę. Jest ona w szczególności związana z wprowadzeniem
poprawionego niedawno pakietu paliwowego, surowszych sankcji karnych (stanowiących adekwatną kryminalizację
zjawisk patologicznych), a także mechanizmu podzielonej płatności.
Automatização de Teste de Segurança Móvel com MobiSec
Authors: Florencio Mendonça Mariano , Santos Souza Layse , Lima do Nascimento Isadora , Gomes Rocha Fabio
Published: September 2019

Avaliar o nível de segurança de aplicativos Android, em um ambiente que há uma quantidade significativa de dados sendo transferidos em tempo real, não é uma tarefa fácil, pois a falta de habilidade em executar rapidamente os testes de segurança é imensa. Diante disso, realizar a automatização de testes de segurança é uma atividade de extrema importância, pois é necessário proporcionar uma qualidade de segurança maior tanto ao produto final quanto ao cliente. Neste artigo, é apresentada a ferramenta MobiSec que realiza a automatização de testes de software nos aplicativos do sistema operacional Android através de planos de teste.
A Tecnologia da Informação como Viabilizadora da Divulgação Transparente e Eficaz de Dados Públicos
Authors: I. C. Rodrigues Célio , C. Rodrigues Raffael , Freitas de Menezes Nathalia , Oliveira Vasconcelos Igor
Published: September 2019

Este artigo aborda a divulgação de dados públicos como mecanismo fortalecedor da democracia. A sua disponibilização deve ocorrer de maneira clara, permitindo um maior engajamento da sociedade na sua reutilização em projetos de controle social. O desenvolvimento de soluções tecnológicas criativas pode proporcionar uma melhor manipulação de tais dados, a exemplo da aplicação proposta.
Marketing direto e a estratégia competitiva da indústria de cosméticos
Authors: Schuchmann Beatriz Monica
Published: September 2019

Esta pesquisa buscou referência teórica sobre marketing direito com os principais autores do tema. A metodologia utilizada foi a bibliográfica, com pesquisa exploratória para auxiliar no entendimento do contexto, utilizando a Empresa Avon e seus principais meios de utilização do marketing direto por meio de catálogos atualizados e sua evolução tecnológica disponível online ou pelo site, seja para atendimento aos seus clientes como das revendedoras, por meio da evoluções tecnológicas e a obtenção de vantagem competitiva, baseada em baixo custo e pela ampliação do portfólio produtos.
Academic SEO – increasing the visibility of research output
Authors: Schilhan Lisa , Kaier Christian
Published: September 2019

In times of an ever-increasing information overload, Academic Search Engine Optimization (ASEO) supports findability of relevant information and contributes to the FAIR principles. It enhances efficiency in literature and data search and therefore plays an increasing role in the research lifecycle.

ASEO is an important aspect to consider when preparing a scientific manuscript for publication. Authors can increase the visibility of their papers in library catalogues, databases, repositories and search engines with simple measures like choosing informative author keywords. The more (meta-)data these search algorithms can use, the higher the probability that a data set or paper will show up in a result list. ASEO enables search algorithms and readers to quickly and unambiguously identify relevant content, thus also helping institutions to increase research visibility. In addition, authors and publishers share an interest in describing content in a way that makes it easy to find it.

Librarians, with their extensive knowledge and wealth of experience in literature research and metadata management such as keyword assignment, can provide valuable advice on the role of as correct and complete metadata as possible and on suitable keywords for search algorithms. For this reason, the Publication Services at Graz University Library have recently started offering training and workshops for authors.

The presentation will provide an introduction into strategies to enhance visibility and findability of online content, such as research articles, with some theoretical background as well as practical examples.
A Lightweight 3D Cu Nanowire Network with Phosphidation Gradient as Current Collector for High‐Density Nucleation and Stable Deposition of Lithium
Authors: Zhang Chen , Lyu Ruiyang , Lv Wei , Li Huan , Jiang Wei , Li Jia , Gu Sichen , Zhou Guangmin , Huang Zhijia , Zhang Yunbo , Wu Junqiao , Yang Quan‐Hong , Kang Feiyu
Published: September 2019

Lithium metal anodes with high energy density are important for further development of next‐generation batteries. However, inhomogeneous Li deposition and dendrite growth hinder their practical utilization. 3D current collectors are widely investigated to suppress dendrite growth, but they usually occupy a large volume and increase the weight of the system, hence decreasing the energy density. Additionally, the nonuniform distribution of Li ions results in low utilization of the porous structure. A lightweight, 3D Cu nanowire current collector with a phosphidation gradient is reported to balance the lithiophilicity with conductivity of the electrode. The phosphide gradient with good lithiophilicity and high ionic conductivity enables dense nucleation of Li and its steady deposition in the porous structure, realizing a high pore utilization. Specifically, the homogenous deposition of Li leads to the formation of an oriented texture on the electrode surface at high capacities. A high mass loading (≈44 wt%) of Li with a capacity of 3 mAh cm−2 and a high average Coulombic efficiency of 97.3% are achieved. A lifespan of 300 h in a symmetrical cell is obtained at 2 mA cm−2, implying great potential to stabilize lithium metal.
Advanced Multifunctional Field Effect Devices Using Common Gate for Both 2D Transition‐Metal Dichalcogenide and InGaZnO Channels
Authors: Yu Sanghyuck , Cho Yongjae , Lim June Yeong , Kwon Hyeokjae , Jeong Yeonsu , Kim Jungcheol , Cheong Hyeonsik , Im Seongil
Published: September 2019

Various functions are introduced from a unique field‐effect device structure which combines or merges transition metal dichalcogenide (TMD) and InGaZnO (IGZO) channels together on one common gate: multivalue field effect transistors (FETs), photodetecting devices, and signal frequency doublers. Judging by the individual transfer characteristics of two FET devices, the n‐IGZO FET always shows higher drain current and more positive‐side turn‐on voltage than those of n‐TMD channel FETs. As a result, a combined transfer characteristic presents two‐step drain current levels, so that their load‐resistance inverter might demonstrate three value output voltage signals. Those ternary value inverter devices with n‐IGZO/n‐ReSe2 or n‐IGZO/n‐WSe2 combination also operate as a photodetector, responding to visible/near infrared (IR) photons with a fast photodynamics of 30 ms rising/falling time. The most interesting is the ambipolar device achieved from n‐IGZO FET/p‐MoTe2 FET combination circuit. The ambipolar device circuit operates as an alternating current (AC) signal frequency doubler and demonstrates twofold organic light emitting diode blinking in one AC period. This unprecedented technique for the multifunctional field effect TMD devices incorporating n‐IGZO FETs will open a new path toward future electronics.
Contorted Polycyclic Aromatic Hydrocarbons with Two Embedded Azulene Units
Authors: Yang Xuan , Rominger Frank , Mastalerz Michael
Published: September 2019

Polycyclic aromatic hydrocarbons (PAHs) that contain both five‐ and seven‐membered rings are rare, and those where these rings are annulated to each other and build azulene units have, to date, mainly been generated in minute amounts on surfaces. Herein, a rational approach to synthesize soluble contorted PAHs containing two embedded azulene units in the bulk is presented. By stepwise detachment of tert‐butyl groups, a series of three azulene embedded PAHs with different degrees of contortion has been made to study the impact of curvature on aromaticity and conjugation. Furthermore, the azulene PAHs showed high fluorescence quantum yields in the NIR regime.
Ultrafast Intercalation Enabled by Strong Solvent–Host Interactions: Understanding Solvent Effect at the Atomic Level
Authors: Zhu Yue , Ji Yujin , Ju Zhengyu , Yu Kang , Ferreira Paulo J. , Liu Yuanyue , Yu Guihua
Published: September 2019

Solvents play an essential role in many areas of chemistry and is the cornerstone of understanding reactivity in solution‐phase reactions. Solvent effects have been widely observed in intercalation reactions; however, understanding of the influence of solvents on the thermodynamics and kinetics remains largely elusive in intercalation chemistry. Now, the solvent‐dependent kinetics of ferrocene intercalation into a layered vanadyl phosphate (VOPO4⋅2 H2O) host is presented, with a special focus on primary alcohols. From methanol to 1‐hexnaol, the intercalation rate peaks in 1‐propanol (80 times faster than the slowest case in methanol). Similar kinetics of exfoliation are also found in these solvents without ferrocene. The correlation between intercalation and exfoliation is understood at atomic level by DFT calculations, which reveal the role of pre‐intercalated solvent molecules play in intralayer interactions, interlayer expansion, and layer sliding.
A case of autism spectrum disorder with cleft lip and palate carrying a mutation in exon 8 of AUTS2
Authors: Saeki Saki , Enokizono Takashi , Imagawa Kazuo , Fukushima Hiroko , Kajikawa Daigo , Sakai Aiko , Tanaka Mai , Ohto Tatsuyuki , Suzuki Hisato , Uehara Tomoko , Takenouchi Toshiki , Kenjiro Kosaki , Takada Hidetoshi
Published: September 2019

We report a patient with autism and cleft lip and palate carrying a de novo heterozygous AUTS2 mutation, c.1464_1467del ACTC (p.Tyr488*). Although the causal relationship between cleft lip and palate and this mutation is unclear, this case report may expand the clinical phenotype of AUTS2 syndrome.
Single‐track year‐round education for improving academic achievement in U.S. K‐12 schools: Results of a meta‐analysis
Authors: Fitzpatrick Dan , Burns Jason
Published: September 2019

Background

Research shows that over summer break, students forget approximately 1 month of learning in math and reading; furthermore, some studies find that low‐income students lose ground relative to peers. Year‐round education (YRE) redistributes schooldays to shorten summer. Prior analyses pooled single‐track YRE (academic intervention in which all students attend school on a common calendar) and multitrack YRE (fiscal intervention countering overcrowding, in which groups of students attend school on staggered schedules).

Search Methods

Systematic search of 22 online databases in summer 2017 yielded 494 de‐duplicated results; 81 warranted full‐text examination. After applying selection criteria, nine studies met criteria but did not report data that allowed effect size calculation. Thirty studies constituted our analytic sample.

Selection Criteria

Studies needed to be of K‐12 single‐track YRE (not multitrack, not a mix of single‐ and multitrack, and not a study that did not specify track), with no accompanying extended instructional time. Studies needed to be from 2001 to 2016, include outcome data, and include a comparison group.

Data

We extracted 55 math g, 58 reading g, 29 math odds ratio, and 27 reading odds ratio effect sizes.

Results

Students at single‐track YRE schools show modestly higher achievement in both math and reading—by a magnitude similar to estimates of summer learning loss—but comparable proficiency. Unexpectedly, the effect was no greater for historically disadvantaged students. Math effects may be larger in middle than elementary school, but the reason is unclear. Importantly, studies of schools that shortened summer to the fewest weeks showed the largest effects in both subjects.
Developing efficient and effective behavioral treatment for insomnia in cancer survivors: Results of a stepped care trial
Authors: Zhou Eric S. , Michaud Alexis L. , Recklitis Christopher J.
Published: September 2019

Background

Insomnia is common among cancer survivors. Although behavioral treatments for insomnia are effective, access is limited. Stepped care delivery models may provide insomnia treatment that is more efficient and accessible to cancer survivors.

Methods

Fifty‐one survivors (mean age, 55 years) with elevated Insomnia Severity Index (ISI) scores (≥12) first participated in Sleep Training Education Program (STEP)‐1: a single, sleep education session. Those reporting elevated ISI scores 1 month later were offered STEP‐2: a 3‐session, group cognitive behavioral treatment for insomnia that has been demonstrated to be efficacious. Participants were considered treatment responders if their ISI score improved by ≥6 points and were considered as having remitted if their posttreatment ISI score was <12. Mood was assessed with the Profile of Mood States–Short Form (POMS‐SF).

Results

Following STEP‐1, ISI scores improved (17.1 to 11.2; P < .001), with 45% responding and 41% remitted. Insomnia remission after STEP‐1 was associated with lower insomnia severity and shorter duration of sleep problems at baseline. Of the 30 (59%) survivors with unremitted insomnia after STEP‐1, 14 (47%) participated in STEP‐2. Following STEP‐2, ISI scores improved (16.9 to 8.8; P < .001), with 79% responding and 71% remitted. STEP‐2 participation was associated with interest in sleep treatment at baseline, but not demographic/health‐related variables. Mood improved significantly following both STEP‐1 and STEP‐2 (P < .001).

Conclusion

A stepped care approach to treating insomnia among cancer survivors has the potential to improve treatment accessibility. A sizable proportion of survivors can benefit from 2 different low‐intensity approaches that could be delivered by nonsleep specialists. For individuals who require more intensive care, assessing treatment interest can identify those who are likely to engage.
Solvent‐Free N‐Alkylation of Amides with Alcohols Catalyzed by Nickel on Silica–Alumina
Authors: Charvieux Aubin , Le Moigne Louis , Borrego Lorenzo G. , Duguet Nicolas , Métay Estelle
Published: September 2019

The N‐alkylation of phenylacetamide with benzyl alcohol has been studied using Ni/SiO2–Al2O3. In the optimized conditions, the desired product was isolated in an excellent 98 % yield. The reaction could advantageously be performed in neat conditions, with a slight excess of amide and a catalytic amount of base. These conditions were tested on a large range of amides and alcohols, affording 24 compounds in 13 to 99 % isolated yields.
Infection in patchy populations: Contrasting pathogen invasion success and dispersal at varying times since host colonization
Authors: Nørgaard Louise S. , Phillips Ben L. , Hall Matthew D.
Published: September 2019

Repeated extinction and recolonization events generate a landscape of host populations that vary in their time since colonization. Within this dynamic landscape, pathogens that excel at invading recently colonized host populations are not necessarily those that perform best in host populations at or near their carrying capacity, potentially giving rise to divergent selection for pathogen traits that mediate the invasion process. Rarely, however, has this contention been empirically tested. Using Daphnia magna, we explored how differences in the colonization history of a host population influence the invasion success of different genotypes of the pathogen Pasteuria ramosa. By partitioning the pathogen invasion process into a series of individual steps, we show that each pathogen optimizes invasion differently when encountering host populations that vary in their time since colonization. All pathogen genotypes were more likely to establish successfully in recently colonized host populations, but the production of transmission spores was typically maximized in either the subsequent growth or stationary phase of host colonization. Integrating across the first three pathogen invasion steps (initial establishment, proliferation, and secondary infection) revealed that overall pathogen invasion success (and its variance) was, nonetheless, highest in recently colonized host populations. However, only pathogens that were slow to kill their host were able to maximize host-facilitated dispersal. This suggests that only a subset of pathogen genotypes—the less virulent and more dispersive—are more likely to encounter newly colonized host populations at the front of a range expansion or in metapopulations with high extinction rates. Our results suggest a fundamental trade-off for a pathogen between dispersal and virulence, and evidence for higher invasion success in younger host populations, a finding with clear implications for pathogen evolution in spatiotemporally dynamic settings.
A Deactivation Factor of Fibrogenic Hepatic Stellate Cells Induces Regression of Liver Fibrosis in Mice
Authors: Nakano Yasuhiro , Kamiya Akihide , Sumiyoshi Hideaki , Tsuruya Kota , Kagawa Tatehiro , Inagaki Yutaka
Published: September 2019

Background and Aims

Hepatic stellate cells (HSCs), a key player in the progression of liver fibrosis, are activated by various inflammatory stimuli and converted to myofibroblast‐like cells with excessive collagen production. Despite many attempts to suppress activation of HSCs or inhibit collagen production in activated HSCs, their clinical applications have not been established yet. Recently, the deactivation of HSCs has been reported as a mechanism underlying the reversibility of experimental liver fibrosis. In the present study, we sought for deactivation factors of HSCs that induce regression of established liver fibrosis.

Approach and Results

We identified transcription factor 21 (Tcf21) as one of the transcription factors whose expression was up‐regulated in parallel to the differentiation of fetal HSCs. Expression of Tcf21 in HSCs remarkably decreased during culture‐induced activation in vitro and in murine and human fibrotic liver tissue in vivo. This reduced Tcf21 expression was recovered during the spontaneous regression of murine liver fibrosis. Tcf21 was also examined for its effects by adeno‐associated virus serotype 6‐mediated Tcf21 gene transfer into cultured activated HSCs and mice with carbon tetrachloride‐ or methionine‐choline deficient diet‐induced liver fibrosis. Overexpression of Tcf21 in activated HSCs not only suppressed fibrogenic gene expression but also restored cells, at least in part, to a quiescent phenotype both in vitro and in vivo. These phenotypic changes of HSCs were accompanied by the regression of steatohepatitis and fibrosis and improved hepatic architecture and function.

Conclusions

Tcf21 has been identified as a deactivation factor of fibrogenic HSCs, providing insight into a treatment strategy for the otherwise intractable liver fibrosis.
On a question of Thas on partial 3‐(qn + 1, q + 1, 1) designs
Authors: Metsch Klaus , Van de Voorde Geertrui
Published: September 2019

In this note, we answer a question of JA Thas about partial ‐ designs. We then extend this answer to a result about the embedding of certain partial ‐ designs into Möbius planes.
Environmental DNA Sampling of Small-Bodied Minnows: Performance Relative to Location, Species, and Traditional Sampling
Authors: Robinson Anthony T. , Paroz Yvette M. , Clement Matthew J. , Franklin Thomas W. , Dysthe Joseph C. , Young Michael K. , McKelvey Kevin S. , Carim Kellie J.
Published: September 2019

We performed experiments in southwestern USA streams to evaluate the efficacy of environmental DNA (eDNA) sampling for two rare small-bodied minnows: Spikedace Meda fulgida and Loach Minnow Rhinichthys cobitis. We collected eDNA by filtering 5-L samples and compared detection sensitivity of eDNA assays to traditional sampling methods (electrofishing and seining) by using both techniques at 33 sites in seven streams. We used caged-fish experiments to estimate eDNA production rates, persistence, and travel distances and to estimate relationships between fish density, biomass, and eDNA quantity. Loach Minnows were detected at 22 sites by both eDNA and traditional sampling, were not detected by either technique at 7 sites, and were detected only by eDNA at 4 sites. Spikedace were detected with both techniques at 15 sites, were not detected by either technique at 8 sites, and were detected only by eDNA at 7 sites. In the Verde River and Wet Beaver Creek, both species’ eDNA was detected downstream of caged fish out to our maximum sampling distance of 500 m. Estimated eDNA production rates were greater for Spikedace than for Loach Minnows, although more Spikedace were used. Production rates for both species were greater in the Verde River than in Wet Beaver Creek. Persistence of eDNA did not differ among species but was greater in Wet Beaver Creek than in the Verde River. In density experiments, the amount of Spikedace eDNA was positively related to the density and biomass of caged Spikedace, but the relationship differed between streams. We conclude that eDNA surveys are more sensitive than traditional methods for detecting rare minnows in southwestern streams. With the sensitivity to detect even a single fish in a 100-m reach, managers will be able to more effectively identify reaches occupied by threatened or endangered fish, even if a population is in decline.
Magnetic Properties of Poly(trimethylene terephthalate‐block‐Poly(tetramethylene oxide) Copolymer Nanocomposites Reinforced by Graphene Oxide–Fe3O4 Hybrid Nanoparticles
Authors: Szymczyk Anna , Paszkiewicz Sandra , Typek Janusz , Špitalský Zdenko , Janowska Izabela , Żołnierkiewicz Grzegorz , Guskos Nikos
Published: September 2019

Thermoplastic elastomeric nanocomposites based on poly(trimethylene terephthalate‐block‐poly(tetramethylene oxide) copolymer (PTT‐PTMO) and graphene oxide (GO)–Fe3O4 nanoparticles hybrid are prepared by in situ polymerization. Superparamagnetic GO–Fe3O4 hybrid nanoparticles before introducing to elastomeric matrix are characterized by X‐ray photoelectron spectroscopy (XPS), X‐ray diffraction (XRD), thermogravimetric analysis (TGA), and scanning electron microscopy (SEM). The effect of loading (0.3 and 0.5 wt%) of GO–Fe3O4 nanoparticle hybrid on the phase structure, tensile, and magnetic properties of synthesized nanocomposites is investigated. The phase structure of nanocomposites is evaluated by differential scanning calorimetry (DSC) and dynamic mechanical thermal analysis (DMTA). Dispersion of GO–Fe3O4 nanoparticles in elastomeric matrix is evaluated by transmission electron microscopy (TEM). Magnetic properties of GO–Fe3O4 nanoparticle hybrid and nanocomposites with their content are characterized using two different techniques: direct current superconducting quantum interference device (dc SQUID) magnetization measurements as a function of temperature (from 2 to 300 K) and external magnetic field and ferromagnetic resonance (FMR) at microwave frequency.