bluuebunny/crossref_metadata_2025 huggingface dataset:
Guillain-Barré syndrome in a child with COVID-19 associated multi system inflammatory syndrome
Authors: Erubothu Alekhya , Rudrappa Sudha , Patagar Pratibha Manjunath
Published: October 2021

Multi-system inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 is a new entity affecting a small percentage of children during the COVID-19 pandemic. This usually presents with multi-organ dysfunction, predominantly affecting cardiovascular, muco-cutaneous, and gastrointestinal systems. Till now, neurological manifestations as a part of this spectrum, such as, encephalopathy, inflammatory CNS syndromes, cerebrovascular disease, and Guillain-Barré syndrome (GBS), have been well reported in adults, but there is a paucity of data from the paediatric age group. Here, we present a case of a 6-year-old girl who presented to us with progressive, bilaterally symmetrical ascending weakness of lower limbs followed by upper limbs along with drooling of saliva and dyspnea. Nerve conduction studies showed motor axonal neuropathy suggestive of GBS and child was treated accordingly with intravenous immunoglobulin. On 4th day of admission, the child developed high grade fever spikes, hypotension and diarrhoea. Hence, worked up for MIS-C which revealed elevated inflammatory markers with positive SARS-CoV-19 IgM, IgG antibodies. The diagnosis was hence revised to GBS with MIS-C, the child was then started on methylprednisolone following which the child showed both clinical and biochemical improvement and was then discharged. A high index of suspicion for the possibility of MIS-C should be kept in mind in the present pandemic times, as the immune-mediated damages in MIS-C are potentially treatable with a timely institution of intensive care measures along with the use of steroids, IV-Ig, and plasmapheresis.
Abdominal migraine in children-An underdiagnosed entity
Authors: Balaji Radha
Published: October 2021

Abdominal migraine is one of the causes for chronic and recurrent abdominal pains, characterised by recurrent episodes and paroxysms of moderate to severe abdominal pain. Here, we share a case of recurrent severe abdominal pain in a 9-year-old girl who was treated over a period of three months for giardiasis, chronic appendicitis and H. pylori infection, in that order. However, after she was correctly diagnosed with abdominal migraine and accordingly treated with drugs used for the treatment of migraine headaches such as propranolol, flunarizine, cyproheptadine and ergotamine tartrate, she responded well to this regimen.
Rare presentation of subcutaneous panniculitis-like T cell lymphoma in pediatric age group
Authors: T. Chandra Lekha , Thahmi Fathima , N. Nijaguna , Srinivas Sahana N.
Published: October 2021

Leukaemia and lymphoma are the commonly seen malignancies in children, subcutaneous panniculitis-like T-cell lymphoma (SPTL) is not only a rare cause of malignancy but also rare cause of panniculitis in children. We report an unusual presentation of this malignancy in the form of pyrexia of unknown origin (PUO), where rash was seen as very late symptom. Histopathology is seen as key in diagnosis of the disorder.
Imaging findings in Fetus-in-fetu-misdiagnosed commonly as teratoma
Authors: R. Rajakumar , Singhal Annu , Sana Sana , Vani Kavita
Published: October 2021

Fetus in fetu is a rare condition associated with abnormal embryogenesis in a diamniotic, monochorionic pregnancy, wherein one of the fetus is enclosed within the body of another normally developing fetus. It should be differentiated from a teratoma because of the later’s malignant potential. Here we report a case of 2 months old girl child who presented with complaints of abdominal distension. USG showed a solid cystic retroperitoneal mass resembling an anencephalic fetus. Contrast enhanced Computed tomography (CT) showed similar findings with visualization of bones resembling femur, sacrum and vertebrae. Findings were correlated with MRI and post-op pathology. The preoperative diagnosis of FIF is based on the observation of vertebral column or limbs in a mass on imaging modalities and our case meets the required criteria.
Relación exhumación-deformación cenozoica de la Serranía del Interior Occidental, Venezuela, mediante modelado termocinemático 2D
Authors: Rodríguez-Lara Ana Jazmín , Bermúdez Mauricio A. , Pérez de Armas Jaime
Published: October 2021

En el centro-norte de Venezuela se encuentra la Cordillera de la Costa, conformada por la Serranía del Interior y la Serranía del Litoral, separadas por el Sistema de Fallas La Victoria. Esta investigación combina restauración estructural y modelado termocinemático 2D, edades de trazas de fisión en apatitas, datos sismológicos y flujos de calor de la zona, para reconstruir la historia de deformación y asociar la actividad de las fallas a la sismicidad presente. Se elaboró un mapa de fallas cuaternarias asociadas con el comportamiento termal y la actividad sísmica. El modelado termocinemático 2D permitió predecir edades en superficie e historias tiempo-Temperatura, las cuales fueron comparadas con datos observados en la zona de estudio. Nuestros resultados sugieren que las rocas fueron enterradas hasta el Eoceno, cuando la placa del Caribe choca con la parte central norte de Suramérica. Discriminamos 4 pulsos tectónicos de enfriamiento: 48 a 40 Ma, 40 a 23 Ma, 23 a 5 y 5 a 0 Ma. El primero relacionado con la convergencia entre las placas del Caribe y Sudamericana, causando el emplazamiento de las Napas de Lara, el segundo relacionado con el enfriamiento causado por la subducción de la placa del Caribe por debajo del cinturón deformado del Caribe, el tercero corresponde a la continuación de la subducción de la placa del Caribe bajo la placa sudamericana, debido a la reactivación de fallas de tipo transpresivo y el último relaciona el avance de la Placa del Caribe hacia el este y la reactivación de importantes sistemas de fallas rumbo-deslizantes. A pesar de que existe una importante actividad sísmica en las montañas del Caribe, en este sector de la Serranía del Interior no se observa una distribución significativa de sismos; adicionalmente, la zona se caracteriza por presentar un flujo de calor medio.
Personificação dos animais: um debate necessário sobre o alcance de categorias jurídicas estruturais
Authors: Saux Edgardo Ignacio
Published: October 2021

O artigo foi pensado enquanto antessala à questão controvertida em exame e que consiste em refletir se o antropocentrismo jurídico se encontra em vias de revisão. Arvorado no método dialético, conclui não ser possível atribuir direitos a animais não humanos o que não significa que o Direito não deva lhes garantir adequada tutela.
We Are All In This Together: Supporting Hearts and Minds During Unprecedented Times
Authors: Hudson Marie-Anne , Huston Lori
Published: October 2021

This article discusses the potential that trauma-informed pedagogy and social-emotional learning practices hold for supporting educators during the COVID-19 pandemic and beyond. The authors bring a critical lens to considering these approaches, noting some limitations and provisos in their use. We advocate for dialogue, mentorship, and professional learning in using them not only to support educators but to authentically include diverse ways of knowing, doing, and being in early childhood environments.
IMPACTO AMBIENTAL DO TEMPO DE CULTIVO NA FERTILIDADE QUÍMICA DE UM ARGISSOLO EM MOSSORÓ-RN CULTIVADO COM MELÃO
Authors: Fernandes Lucimara Batista , Amaro Filho Joaquim , Moura Filho Edmondson Reginaldo , Oliveira Alan Martins de
Published: October 2021

Este trabalho teve como objetivo avaliar os impactos ambientais sobre os atributos químicos em um Argissolo na região de Mossoró, cultivado com melão (Cucumis melo L.), em função do tempo de cultivo. O estudo foi conduzido na Fazenda Jardim, município de Mossoró - RN. A seleção das áreas foi realizada levando-se em consideração quatro (04) tempos de uso, sendo uma área de mata nativa, uma área com dois anos de cultivo, outra com dois anos e meio e uma quarta área com três anos de cultivo. Em cada área escolhida, foi realizada a coleta de amostras de solo em 10 pontos aleatórios, em três profundidades (0-20, 20-40 e 40-60 cm). As sub-amostras foram misturadas, para cada profundidade, e dividida em três amostras. Estas foram conduzidas ao Laboratório da Universidade Federal Rural do Semi-Árido (UFERSA), para realização das análises química. O delineamento utilizado foi o inteiramente casualisado, em esquema fatorial 4 x 3 (quatro tempos de uso e três profundidades), com três repetições. As médias foram comparadas pelo teste de Tukey ao nível de 5% de probabilidade. Verificou-se que o tempo de cultivo influenciou todas as variáveis químicas, exceto magnésio. Apenas as variáveis pH, condutividade elétrica, matéria orgânica, fósforo e potássio apresentaram alterações significativa nas camadas de solo estudadas. Com as práticas atuais de manejo adotadas, não há riscos iminentes de degradação do solo.
Requirements for Additional Strength Biowaivers for Modified Release Solid Oral Dosage Forms in International Pharmaceutical Regulators Programme Participating Regulators and Organisations: Differences and Commonalities
Authors: Roost Matthias Shona , Potthast Henrike , Walther Chantal , García-Arieta Alfredo , Abalos Ivana , Agostinho Freitas Fernandes Eduardo , Mendes Lima Santos Gustavo , Rodríguez Martínez Zulema , Tam Andrew , Rodrigues Clare , Gutierrez Triana Diego Alejandro , Guzmán Aurela Erwin , Rodríguez Rodríguez Nayive , Aeh Park Sang , Kim Jayoung , Kariv Rami , Divinsky Milly , Jones Ben , Kuribayashi Ryosuke , Myoenzono Aya , Kasuga Miho , Van Oudtshoorn Joy , Chi Jo-Feng , Hung Wen-Yi , Hsu Li-Feng , Crane Christopher , Jarman Tony , Braddy April
Published: October 2021

This article describes an overview of waivers of in vivo bioequivalence studies for additional strengths in the context of the registration of modified release generic products and is a follow-up to the recent publication for the immediate release solid oral dosage forms. The current paper is based on a survey among the participating members of the Bioequivalence Working Group for Generics (BEWGG) of the International Pharmaceutical Regulators Program (IPRP) regarding this topic. Most jurisdictions consider the extrapolation of bioequivalence results obtained with one (most sensitive) strength of a product series as less straightforward for modified release products than for immediate release products. There is consensus that modified release products should demonstrate bioequivalence not only in the fasted state but also in the fed state, but differences exist regarding the necessity of additional multiple dose studies. Fundamental differences between jurisdictions are revealed regarding requirements on the quantitative composition of different strengths and the differentiation of single and multiple unit dosage forms. Differences in terms of in vitro dissolution requirements are obvious, though these are mostly related to possible additional comparative investigations rather than regarding the need for product-specific methods. As with the requirements for immediate release products, harmonization of the various regulations for modified release products is highly desirable to conduct the appropriate studies from a scientific point of view, thus ensuring therapeutic equivalence.
Specific Motivation of Psychological online Consultations Customers
Authors:   Saratov State Technical University named after Gagarin Yu. A., Abrosimova Yu. A.
Published: October 2021

The article discusses the relationship of the motivational sphere of clients with specific requirements of the problems and requests in the format of Internet counseling. A number of problems associated with the motivation of the clients and possible solutions are identified. Recommendations are given on the modeling of psychologist speech activity in providing psychological assistance to them on the Internet.
Evaluation by students of the University Environment Based on the Method the Vector Modeling
Authors:   Institute of Continuous Education of Moscow City University, Yasvin V. A.
Published: October 2021

Presented a method vector modeling learning environments, developed on the basis typology of «educative environment» J. Korczak. It is shown that the majority of students assesses university environment as an environment conducive to personal and social passivity of graduates. Identified p edagogical conditions that provide an assessment of the university environment graduate students of some universities, like stimulating their educational activity.
Business Model for a Post Pandemic Startup In Indian Fast Moving Consumer Goods FMCG sector
Authors: Sharma Anup , Kumar Arya Sudhir , Parekh Shubham , Nagendraverma Chandrasena , Ebrahim Nidwan
Published: October 2021

The objective of this study was to come up with a Business model for the post-pandemic startup in the Indian FMCG sectors. For this purpose, a questionnaire was designed to collect the data from various respondents of different gender and age groups. The responses were taken to know what the consumers are preferring and what they choose over at the time of the pandemic. Close-ended questions were prepared to collect the data. The questions included in the questionnaire were designed in such a way that they may give a basic idea of where to hit the ball in the court at the time of the pandemic. We know that COVID-19 has shown us a picture we never thought will ever be there and were not prepared for the same. Therefore, to avoid such kind uncertainties affecting the operations of the well-settled business and also to give confidence to the start-ups that have been affected by the same this study was conducted to know the choice, preference, and other factors affecting the purchasing habits of the consumers. Through the study, we found out that the majority of the consumers are focusing more on their health and are shifting to the products which may help them to build their immunity and keep them immune from the virus. This study can be of great use for start-ups to consider and follow to make sure they grab a huge number of market shares
CHANGES IN OXIDATIVE STRESS BIOMARKERS IN THE FIRST-EPISODE PSYCHOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Ferreira Antunes Neto Joaquim Maria , Nalesso Ana Maria
Published: October 2021

The literature has shown that oxidative stress markers can indicate the degree of disease severity in untreated patients with schizophrenia. There is evidence that the excessive production of free radicals or the installation of oxidative stress can be evidenced at the time of the first-episode psychosis (FEP). Were used the Preferred Reporting Items for Systematic Reviews and Meta-analyses Guidelines to conduct a systematic literature search to detect studies comparing oxidative stress markers in FEP patients and healthy controls (HC). Twenty-one studies were obtained for inclusion in this systematic review, comprising an overall sample of 415 FEP and 392 HC for CAT (6 studies), 1293 FEP and 1279 HC for SOD (15 studies), 500 FEP and 529 HC for GPx (9 studies), 218 FEP and 228 HC for GSH (5 estudies), and 814 FEP and 852 HC for lipid peroxidation (12 studies). By analyzing the standardized mean differences, no significant differences were found between FEP and HC groups in any of the antioxidant defense system parameters assessed, despite favoring a decrease in activity of both the antioxidant and non-enzymatic enzyme systems. Lipid peroxidation levels showed a significant increase for the FEP group compared to the HC group (p < 0.0001). Heterogeneity among studies was high, with I2 values > 90%. Sensitivity analyzes were performed to obtain more homogeneous results. Significant differences were obtained for serum/plasma SOD (p < 0.0001) and lipid peroxidation (p < 0.0001) in the FEP group compared to the HC group, but still containing high heterogeneity. These results suggest that the oxidative stress biomarkers could be used to indicate the degree for the severity of the disease in untreated patients with schizophrenia.
Interaction of Turkey and World Trade within the Framework of the World Trade Organization
Authors: Aytüre Selma , Yücel Ahmet
Published: October 2021

The level and direction of the relationship between WT (World Trade) and TFT (Turkey Foreign Trade) statistically analysed in this study. For this purpose, in addition to some descriptive statistics, correlation and regression algorithms were utilized to observe the relationship. In addition, point, box and line graphs were used to observe the relative distributions of WT and TFT. According to the results, there is a 99.258 % correlation between WT and TFT. In addition, a linear regression model was designed in which TFT was determined as dependent and WT was determined as independent variable. The model is statistically significant at a confidence level of 0.05 and R, R-square and adj.-R-square explanatory ability rates of the model are 99.2 %, 98.5 % and 98.4 %, respectively. The scatter-plot shows that the binary value points are generally distributed around the linear line. In the box-plot, it is observed that WT has a wider range than TFT, but generally both variables have a symmetrical distribution. Finally, the line graph shows the ordered and consequetive 38-year distribution of both variables. Although the distribution is generally parallel to each other, the upward movement of WT has been observed to be sharper and accelerated in the last 10 years. All these results indicate that TFT has a very strong level of relationship with WT and that WT can be used as an important parameter in understanding TFT.
Dyslipidemia, Diabetes Mellitus, Rheumatoid Arthritis: Association Study Between them in a Group of Individuals in Shijak Population
Authors: Shera Brisida
Published: October 2021

The aim of the study was to evaluate the association  between Dyslipidemia, Diabetes Mellitus and Rheumatoid Arthritis in a population of 289 individuals ( 154 female and 135 male ), for the year 2020 ( January – December ) and the year 2021 ( January – July ), where 85.8 % are patients with Diabetes Mellitus ( DM ) , 9.7 % are patients with Dyslipidemia and 4.5 % are patients with Rheumatoid Arthritis ( RA ). Diseases are analyzed separately from each – other calculating the correlation based on the values of the main analytical components for each disease. From this study it was determined that the number of individuals with DM and Dyslipidemia is the highest in the age group VII ( 65 years and above ). The highest average value of glycemia is in the age group V ( 45- 54 years old ), with value 195 mg/ dl for the female gender and 218.4 mg/ dl for the male gender. In individuals with DM has significant correlation values between glycemic – triglycerides with Pearson correlation Value 0.157. Individuals with Diabetes have a high tendency to be affected by Dyslipidemia. In patients with Dyslipidemia significant correlation value are between Cholesterol- Glycemi with Pearson correlation value 0. 555. Individuals with Dyslipidemia have a high tendency to be affected by DM.  In patients with RA the largest number of individuals is in the age group V and VI. Females are in greater number than males. The highest erythrocyte sedimentation rates are in the age group VII, with average value 21.5 mg/ dl. Higher correlation value is between erythrosediment – LDL- Ch with value 0.93. Individuals with RA have a high tendency to be affected by Dyslipidemia. The knowledge gained from this study are important to determine the correct diagnosis for primary and concomitant diseases recognizing risk factors. Prevention of diseases at an early stage and prevention of comorbidities to avoid deteriorating health.
Analysis of The Effect of Conflict on Employee Performance with Training as Mediators in Automotive Company in Medan
Authors: Zhijun Wang
Published: October 2021

The object of exploration is auto organization in Medan. The choice of articles depended on a decrease in representative execution at the organization. Execution is the consequence of work that is surveyed both subjectively and quantitatively about the execution of undertakings and responsibilities regarding the work relegated. Preparing gives freedoms to representatives to foster abilities and capacities to work that can make it simpler for representatives to complete their work. As of late, numerous representatives feel sluggish to work due to questions at work. The exploration utilized a few speculations of the executives of HR identified with preparing, struggle and worker execution. The examination utilized a quantitative exploration approach, this kind of exploration is quantitative. The examination tests were drawn by utilizing immersed inspecting methods. The information assortment was performed by meetings, polls and documentation examines. The examination information were investigated by utilizing various direct relapse investigation, coefficient of assurance, synchronous test (F-test) and Halfway test (T-test). The exploration populaces were 64 representatives with the absolute examples of 64 workers, while 30 workers were utilized for legitimacy and dependability testing taken from other branch organizations. The outcome shows that preparation and struggle to some extent and at the same time significantly affect execution with a coefficient of assurance of 68% in which F-count> F-table (68.239> 3.09) and T-count> T-table (5.304> 1.986) on preparing variable while on struggle variable (3,399> 1,986). Consequently, preparing and struggle have a positive and critical impact on the exhibition of representatives at car organization in Medan.
Rotational Ground-State Bands of Doubly Even-Even 170,172Hf Isotopes
Authors: Hossain I. , Y. Abdullah Hewa , Ahmed I.M. , Fadhil I. Sharrad
Published: October 2021

Using phenomenological fitting, Sood’s semi-empirical formula have been investigated the rotational structure of even-even rare-earth 170,172Hf nuclei. The calculated rotational energies were compared with their corresponding experimental data. It showed that in 172Hf and 170Hf isotopes, calculated energies fits the experimental values to a remarkable degree of accuracy with deviation less than 3 percent at Jπ = 18+ state and Sood’s semi-empirical formula predicted rotational energies.
Effect of Kithul Palm (Caryota urens) Fiber on Subjective Satiety and Food Intake of Normal and Overweight Women in Sri Lanka
Authors: Liyanage Dhanesh , Samarakone Subashinie , Amarasinghe Wishmanthi
Published: October 2021

Dietary fiber plays prominent role in satiety characteristics of meals. Kithul palm flour is a conventional food ingredient consumed in Sri Lanka, believed having superior satiety characteristics. This study aimed to find the subjective satiety characteristics of Kithul flour meal compared to soluble fiber meal (Psyllium) and low fiber meal. Three arm, single blinded, cross over placebo controlled study was designed with three isocaloric treatments (carbohydrate 55%, fat 30% and  protein 15%) having same energy density (~1 kcal/g). Satiety characteristics after ingestion of treatment meal were recorded using Visual Analog Scale (VAS). The Kithul flour meal had significant reduction in hunger (P=0.0025), increment in fullness (P=0.0408), reduction in desire to eat (P<0.0001), and reduced prospective food consumption (P<0.0001) values compared to the Psyllium meal. Further, Kithul flour meal had increased fullness (P=0.0388), reduced desire to eat (P=0.0002), and reduced prospective food consumption (P<0.0001) compared to the low-fiber control meal. Kithul flour meal showed superior satiety results in overweight women compared to normal weight women.
Removal of eriochrome black T from water using a chitosan/zeolite composite: a kinetic study
Authors: Guzmán Grijalva Héctor Manuel , Alvarado Ibarra Juana , Zamarrón Pulé Martín Francisco , Esquer  Peralta Javier
Published: October 2021

A composite material was prepared using chitosan and chabazite for the removal of Eriochrome T black dye from water. Scanning electron microscopy (SEM) analyses showed chabazite particles embedded in the chitosan matrix. Thermogravimetric analyses indicated that chitosan degrades chemically at temperatures above 225 °C; chabazite only experiences weight decrease due to moisture loss. Fourier transform infrared spectroscopy (FTIR) analyses on chitosan detected the presence of O-H, N-H, C-H, C-N and C-O bonds, protonated amino groups and saccharides. In chabazite, H2O molecules, T-O and O-T-O groups, where “T” corresponds to Si or Al atoms, isolated H-bonded O-H groups, and Si-O-Si groups were detected. In kinetic experiments, an 86 % decrease of the dye concentration in solution was achieved in approximately 500 minutes. The linearization method was used to evaluate the fit of the experimental data with the pseudo-first-order, pseudo-second order, Elovich and intra-particle diffusion adsorption kinetic models. The kinetic experiments showed that the sorption mechanism corresponds to a pseudo-second order model.
Solusi Numerik Model Gerak Osilasi Vertikal dan Torsional Pada Jembatan Gantung
Authors: Permata Hendrik Widya , Kusumastuti Ari , Juhari Juhari
Published: October 2021

Model gerak osilasi vertikal dan torsional merupakan model yang menggambarkan gerak osilasi vertikal dan gerak torsional pada batang yang digantung. Gerak osilasi vertikal merupakan gerak naik turun suatu benda yang terjadi terus berulang, dan kemudian pada waktu tertentu akan berhenti atau mengalami redaman. Gerak torsional merupakan getaran sudut dari suatu objek yang mengalami rotasi. Model gerak osilasi dan torsional pada dasarnya merupakan sistem persamaan diferensial orde dua. Tujuan dari penelitian ini adalah untuk mengetahui solusi numerik model gerak osilasi vertikal dan torsional menggunakan metode Adams-Bashforth-Moulton orde empat, lima, dan enam. Model gerak osilasi vertikal dan torsional terlebih dahulu diselesaikan menggunakaan metode Runge-Kutta-Fehlberg orde lima untuk mendapatkan solusi awal kemudian model tersebut diselesaikan menggunakan metode Adams-Bashforth-Moulton orde empat, lima dan enam. Hasil solusi numerik setiap metode Adam-Bashforth-Moulton selanjutnya diuji dengan galat relatif. Hasil simulasi numerik model gerak osilasi vertikal dan torsi diperoleh bahwa gerak osilasi vertikal dan gerak torsional merupakan gerak harmonik teredam dan semakin tinggi orde pada metode Adams-Bashforth-Moulton maka akan lebih cepat galat relatif menuju nilai nol dan sebaliknya
Model Matematika Kurva Kuartik Bezier Hasil Modifikasi Kubik Bezier
Authors: Juhari Juhari
Published: October 2021

The creative industries have become the government's attention for contributing to economic accretion. But due the lack of artistic creativity and appeal, the evolution of creative industries craft section is not optimal. So that it was needed a variations of relief items to increase the attractiveness. In general, industrial objects design are still limited to the space geometry objects or a Bezier curve of degree two. Therefore, Bezier curves of degree is selected and modified it into a quartic Bezier forms and then applied to the design of industrial objects (glassware). The purpose of this research is to determine the formula of quartic Bezier from of qubic Bezier modifications and to determine the rotary surface shape of quartic Bezier from cubic Bezier modifications. Then, from some form of revolving surface of modified cubic Bezier the glassware designs are generated. The results of this research are, first, the formula of quartic Bezier result of Bezier cubic modifications. Second, the form of revolving surface of modified cubic Bezier which is influenced by five control points  and parameter selection . For further Research it is expected to develop a modification of cubic Bezier into Bezier of degree-
TASAVVUFTAKİ SÜREKLİ YARATILIŞ NAZARİYESİNİN MEVLÂNÂ’NIN ŞİİRLERİNDEKİ İZLERİ
Authors: YILDIRIM Ali
Published: October 2021

Varlık yokluk meselesi, varlık diye bildiğimiz unsurların hangi ölçülerle varlık olarak nitelendirilebileceği gibi hususlar dinlerin ve düşünce sistemlerinin en başat konularından olmuştur. Özellikle mevcudatın kadim (ezeli) veya hâdis (sonradan yaratılma) olup olmadığı meselesi, en çok tartışılan ve farklı görüşlerin ileri sürüldüğü konuların başında gelmektir. Buna ilaveten varlık diye bildiğimiz birimlerin Yaratıcı ile olan ilintisi, konumu ve mahiyeti de bu konuda ortaya çıkan meselelerden olmuştur. Klasik kelamcı düşünceye göre Allah, varlığı sonradan ve yoktan yaratmıştır, inancı hâkimken, tasavvuf düşüncesi varlığın Allah’ın bilgisinde ezelden beridir var olması itibarıyla kadim; ancak cisimleşerek varlık alanına çıkması yönüyle hâdis olduğunu ileri sürmüştür.
Mevcudatın kendine yeten bir varlığı olmadığı ve buna bağlı olarak gerek yaratılmada ve gerek yaratılma sonrasında her halükârda Allah’ın varlığına muhtaç olması gerçekliği dile getirilmiştir. İşte bu çerçevede, her an yeniden yeniye yaratma ve yaratılma fiilinin gerçekleştiği tezi ileri sürülmüştür. Bu tezin İslam öncesi felsefi düşünce sistemlerinde de izleri görülmekle birlikte tasavvufta da bir karşılık bulduğu görülmektedir. Özellikle vahdet-i vücut düşüncesini sistematikleştiren İbn Arabî’nin de üzerinde sıklıkla durduğu bu düşüncenin izlerini, Mevlânâ’nın şiirlerinde de bulmaktayız. Başta Mesnevi olmak üzere Divan-ı Kebir, Fîhi Mâ Fîh, Mecâlis-i Seb’a gibi eserlerinde Mevlânâ’nın bu tezi benimsediği görülmektedir.
Practical training of students of University in the administration and the executive authorities of Region as a condition for professional development (on the example of the project “Continuous practice”)
Authors:   Pskov State University, Goncharova E.V. , Filippova T.V.
Published: October 2021

Shown is the role of practical training of students of higher education in the administration and executive authorities of the region in a dispersed format as a condition for professional development and a source of improving the level of soft skills. The article reveals the work experience gained at the Institute of Humanities and Language Communications of the Pskov State University within the framework of the project “Continuous Practice” in 2019–2021. An experimental test of the effectiveness of the proposed methodological approach for involving students in practical training in a dispersed format in the executive authorities of the region was carried out, an increase in the relative number of students who showed medium and high levels of readiness for professional activity was shown.
Documentação fotográfica na UFBA (1946-2010)
Authors: Silva Rita de Cássia Machado da , Toutain Lídia Maria Batista Brandão , Cruz Joseane Oliveira da
Published: October 2021

Este estudo visa a identificação preliminar de forma a inventariar, indexar e, posteriormente, digitalizar a documentação fotográfica para acesso e disseminação da informação imagética diagnóstico do acervo documental das fotografias, existente na Coordenação Lugares de Memória do Sistema Universitário de Bibliotecas da Universidade Federal da Bahia do período 1946-2010.  Teve seu início a partir do diagnóstico do acervo documental das fotografias existente em todas as Bibliotecas do Sistema, e foi iniciada pelo acervo fotográfico do setor Memória. Com base qualitativa e universo exploratório e descritivo, a pesquisa documental fotográfica abrange os reitorados e os eventos na Universidade. O tratamento técnico e o cadastramento está sendo executado por meio do mapeamento em planilha do Excel e inserido na página do Repositório da Universidade Federal da Bahia, na comunidade da Comissão Permanente de Arquivo. O resultado esperado consiste em salvaguardar a memória da instituição ao tempo em que possibilita novos estudos para a comunidade acadêmica.
Pengembangan Sumber Daya Manusia Preparing – Using
Authors: Mashudi Mashudi
Published: October 2021

Syukur Alhamdulillah penulis panjatkan kehadirat Allah SWT yang telah melimpahkan nikmat-Nya yang berupa kesempatan menyelesaikan Penelitian Produk Terapan (PPT) dan menyelesaikan penulisan buku ajar ini. Buku ajar dengan berjudul “Pengembangan Sumber Daya Manusia : Preparing- Using” terinspirasi dari beberapa hasil penelitian di bidang manajemen sumber daya manusia (SDM) yang penulis lakukan dan pengalaman penulis sebagai dosen di perguruan tinggi. Yang penulis rasakan, ketika perguruan tinggi atau lembaga apapun namanya, menerima pegawai maka sejatinya lembaga ini berada dalam fase menggunakan (using) bagi karyawan atau SDM. Jarang bahkan bisa dibilang kurang memperhatikan pada fase persiapan (preparing) dan fase setelah pensiun (pasca-using). Berangkat dari pengalaman itu, maka buku ini terinspirasi membahas ketiga fase yaitu bagaimana menyiapkan SDM, menggunakan SDM, dan bagaimana menyiapkan SDM setelah pensiun. Tentu buku ajar ini masih perlu perbaikan agar semakin sempurna, untuk itu penulis menerima dengan tangan terbuka baik kritik, masukan, maupun saran dari semua pihak.
Wawasan Kebangsaan: Negara Pancasila Sebagai Darul ‘Ahdi Wa Al Syahadah
Authors: Astutik Anita Puji
Published: October 2021

Puji syukur kepada Tuhan Yang Maha Esa, sehingga Buku Wawasan Kebangsaan: Negara Pancasila Sebagai Darul ‘Ahdi wa al Syahadah ini dapat disusun dengan baik meskipun perlu penyempurnaan lebih lanjut. Buku ini menjadi pedoman sosialisasi kepada pelajar maupun mahasiswa untuk meningkatkan kesepahaman tentang komitmen Muhammadiyah tentang wawasan kebangsaan. “Negara Pancasila sebagai Darul ‘Ahdi wa al Syahadah” merupakan komitmen Muhammadiyah untuk terus berkiprah membangun dan meluruskan arah Indonesia sebagai Negara Pancasila yang maju, adil, makmur, bermartabat, dan berdaulat menuju peradaban yang utama dalam ridla Allah Subahanu wa Ta’ala. terhadap aktivisme gerakan Mahasiswa. Belakangan ini, Indonesia diwarnai dengan fenomena radikalisme. Kemandegan suatu ideologi dalam memecahkan masalah yang terjadi merangsang untuk mencari alternatif ideologi lain yang secara empiris dianggap berhasil. Maka tak jarang, kajian-kajian kritis yang kerap dilakukan lewat pengujian terhadap pendekatan ideologi atau metodologis tertentu yang diminati. Hal ini melatarbelakangi perlunya disusun sebuah pedoman sosialisasi sebagai peningkatan kesepahaman tentang wawasan kebangsaan, khususnya mengenai komitmen Muhammadiyah “Negara Pancasila Sebagai Darul ‘Ahdi wa al Syahadah”. Secara keseluruhan buku ini memuat empat pembahasan yang terdiri atas: - Relasi Islam dan Negara Membahas mengenai pandangan terkait dengan relasi konseptual menyangkut agama dan negara, hubungan antara Islam dan politik di era kontemporer. - Muhammadiyah dan Wawasan kebangsaan Menjelaskan tentang pengertian wawasan kebangsaan, peran historis Muhammadiyah sebagai bagian integral bangsa Indonesia dan kontribusinya dalam keberlangsungan negara Indonesia serta komitmen Muhammadiyah dalam mengisi kehidupan kebangsaan.
Case Study: An Approach for Hydraulic Fracturing Minifrac G-Function Analysis in Relation to Facies Distribution in Multilayered Clastic Reservoirs
Authors: Jatykov T. , Bimuratkyzy K.
Published: October 2021

An industry-accepted standard for minifrac analysis for evaluating and improving design of hydraulic fracturing treatments originated from the original Nolte analysis (Nolte 1979) of pressure decline, followed by the introduction of Castillo G-function in a Cartesian plot (Castillo 1987). The latter provides a graphical method for the identification of fracture closure pressures and stresses with subsequent derivation of other parameters such as fluid efficiency and fracture geometry.

With the introduction of a more advanced consideration of the G-function interpretation for various reservoir conditions (Barree et al. 2007), subdividing the interpretation into calculations based on flow regimes and leakoff modes, this approach has become even more sophisticated. Particularly, interesting flow regimes and leakoff modes during fracture closure include the fracture height recession mode. This mode tends to result in rapid screenout and difficulty in placing high proppant concentrations. Regarding interpretation, the G-function derivative curve for this mode can have more than one plateau, an outcome that is possibly indicative of features that have not been widely considered to date or on which little to no data have been published.

This paper presents a case study as an example of such height recession mode, along with a subsequent G-function interpretation and analysis and with consideration of the vertical facies distribution along the wellbore. Considerable attention is paid to the G-function derivative plateau analysis. Three distinctive wells, namely X-1, X-2, and X-3, are discussed. Using this technique can lead to an improved fracture calibration, optimized fracture design, and adoption of a successful completion strategy; additionally, the confirmation of 1D facies distribution can provide new insights into the fracture closure period.
ENRICH: Exploiting Image Similarity to Maximize Efficient Machine Learning in Medical Imaging
Authors: Chinn Erin , Arora Rohit , Arnaout Ramy , Arnaout Rima
Published: October 2021

Deep learning (DL) requires labeled data. Labeling medical images requires medical expertise, which is often a bottleneck. It is therefore useful to prioritize labeling those images that are most likely to improve a model's performance, a practice known as instance selection. Here we introduce ENRICH, a method that selects images for labeling based on how much novelty each image adds to the growing training set. In our implementation, we use cosine similarity between autoencoder embeddings to measure that novelty. We show that ENRICH achieves nearly maximal performance on classification and segmentation tasks using only a fraction of available images, and outperforms the default practice of selecting images at random. We also present evidence that instance selection may perform categorically better on medical vs. non-medical imaging tasks. In conclusion, ENRICH is a simple, computationally efficient method for prioritizing images for expert labeling for DL.
LncRNA NEAT1 Facilitates Glioma Progression via Stabilizing PGK1
Authors: Liang Jingshan , Liu Changtao , Xu Dezhi , Xie Kang , Li Aimin
Published: October 2021

Background: Long noncoding RNA NEAT1 has been implicated in glioma progression. However, the effect of NEAT1 on glycolysis of glioma cell and the potential mechanism remain unclear.Methods: In vitro experiments, including CCK-8, colony formation, ECAR, and lactate detection assays were performed to evaluate the effect of NEAT1 on proliferation and glycolysis of glioma cell. RNA pulldown and RIP assays were performed to identify the interaction between NEAT1 and PGK1. Truncated mutation of NEAT1 and PGK1 was used to confirm the specific interactive domains between NEAT1 and PGK1. Animal studies were performed to analyze the effect of NEAT1/PGK1 on glioma progression. Results: NEAT1 knockdown significantly suppressed the proliferation and glycolysis of glioma cells. NEAT1 could specifically interact with PGK1, which promotes PGK1 stability. Hairpin A of NEAT1 is essential for interaction with M1 domain of PGK1. Depletion of NEAT1 markedly inhibited tumor growth in mice, while PGK1 could reverse this effect. Higher expression of NEAT1 was associated with poor overall survival of GBM patients.Conclusions: NEAT1 over expression promotes glioma progression through stabilizing PGK1. NEAT1/PGK1 axis is a candidate therapeutic target for glioma treatment.
Removal of molybdenum from wastewater using modified amino-functional framework: a study of the adsorption properties
Authors: Saghian Mahdie , Dehghanpour Saeed , Sharbatdaran Massoomeh
Published: October 2021

Herein, we have employed a convenient method to study kinetic and thermodynamic parameters of the adsorption of molybdenum from wastewater by using modified Zr-based metal-organic frameworks, UIO-66-NH 2 -X, as adsorbents. The frameworks were fabricated with a simple and fast method from terephthalic acids and Zirconium metal ions and modified via introduction of aldehyde groups using imine condensation. This is the first report in which MOFs have been utilized as adsorbents in molybdenum adsorption. The prepared adsorbents show high adsorption efficiency which is representative of an improvement compared to other literature. The experimental adsorption data could be well interpreted with the pseudo-second-order kinetics and the Langmuir isotherm model. Thermodynamic studies illustrated an exothermic spontaneous mechanism for the adsorption process.
Layered Feedback Control Overcomes Performance Trade-off in Synthetic Biomolecular Networks
Authors: Hu Chelsea , Murray Richard
Published: October 2021

Layered feedback is an optimization strategy in feedback control designs widely used in electrical and mechanical engineering. Layered control theory suggests that the performance of controllers is bound by the universal robustness-efficiency trade-off limit, which could be overcome by layering two or more feedbacks together. In natural biological networks, genes are often regulated with redundancy and layering to adapt to environmental perturbations. Control theory hypothesizes that this layering architecture is also adopted by nature to overcome this performance trade-off. In this work, we validated this property of layered control with a synthetic network in living E. coli cells. We performed system analysis on a node-based design to confirm the trade-off properties before proceeding to simulations with an effective mechanistic model, which guided us to the best performing design to engineer in cells. Finally, we interrogated its system dynamics experimentally with eight sets of perturbations on chemical signals, nutrient abundance, and growth temperature. For all cases, we consistently observed that the layered control overcomes the robustness-efficiency trade-off limit. This work experimentally confirmed that layered control could be adopted in synthetic biomolecular networks as a performance optimization strategy. It also provided insights in understanding genetic feedback control architectures in nature.
Research on Active Pressurized Forced Lubrication Deep Drawing Process and Evaluation of Lubrication Effect
Authors: Chen Duan , Zhao Changcai , Chen Xiaoyi , Li Haoyang , Zhang Xin
Published: October 2021

Friction and lubrication are important parameters that affect the quality of sheet metal forming, excellent lubrication condition and less harmful friction can reduce local thinning of sheet metal, delay fracture and improve surface quality. Aiming at the poor friction conditions and difficult lubrication in the flange area during deep drawing, an active pressurized forced lubrication deep drawing(FLDD) process was proposed in this paper. A hydraulic system was employed to flush high pressure lubricating oil into the contact gap between die and sheet in the flange area. The high pressure hydrostatic oil film in the contact gap can reduce the real contact area and improve the lubrication condition effectively. The equipment is simple, the cost is low, and lubricating oil pressure can be measured and controlled. Under the conditions of 20kN, 35kN and 50kN blank holder force(BHF), FLDD test of box parts was carried out with 5MPa and 9MPa pressure water-based lubricating oil. The horizontal comparison experiment was conducted with common lubricating media such as polyethylene film(PE film), high-purity molybdenum disulfide particles, vegetable oil and water-based lubricating oil under the same process conditions. Lubrication effect was evaluated by obtaining test data. Test results illustrated that the lubrication effect of high-purity molybdenum disulfide particles was the best and that of vegetable oil was the worst. The lubrication effect of water-based mineral lubricant was significantly improved after pressurization. The maximum forming height was increased by 17.97%, the maximum forming force was reduced by 8.9%, the maximum wall thickness thinning rate was reduced by 7%, and the lubrication effect of 9MPa pressure was superior to that of 5MPa. Although there is still a certain shortfall with special lubricating media such as high-purity molybdenum disulfide, FLDD process has definite application value in improving production environment, pollution control and automatic production.
Dipeptidyl Peptidase-4 Inhibitor Administration Is Associated with Higher Eosinophil Counts and Batter Clinical Outcomes in Patients with Aorta Intramural Hematoma
Authors: chen qu , Jiang Dandan , shan zhonggui
Published: October 2021

Objectives Investigating whether dipeptidyl peptidase-4 (DPP-4) inhibitors could influence clinical outcomes in intramural hematoma (IMH) patients with diabetes mellitus (DM). Methods IMH patients who received a "wait and watch strategy" were included. Cox proportional hazard models were constructed to identify potential risk factors. A Kaplan–Meier survival analysis was used to estimate all-cause and aorta-related mortality during the follow-up period. Results From January 2000 to December 2020, 1094 IMH patients were divided into group A (n=572, IMH patients without DM), group B (n=191, IMH patients with DM and receiving oral antidiabetic drugs [without admission of DDP-4 inhibitors]) and group C (n=331, IMH patients with DM and receiving oral antidiabetic drugs [including admission of DDP-4 inhibitors]). Group C had the lowest rate of aorta-related adverse events (6.4%), aorta-related mortality (1.2%) and reintervention (5.2%). Cox proportional hazard models revealed that lower eosinophil count (per 0.1, hazard ratio [HR], 0.61; 95% confidence interval [CI], 0.51-0.73, P< 0.001) and thicker hematoma thickness (HR, 1.22; 95% CI, 1.06-1.39, P <0.001) were associated with higher occurrences of aorta-related adverse events. Lower eosinophil count (per 0.1, HR, 0.24; 95% CI, 0.15-0.40, P <0.001), larger descending aorta diameters (HR, 1.12; 95% CI, 1.02-1.23, P <0.021), and thicker hematoma thickness (HR, 3.25; 95% CI, 2.36-4.46, P <0.001) were also associated with increased aorta-related mortality. Kaplan-Meier survival analysis revealed a significant decrease in all-cause and aorta-related mortality in group C ( P <0.001). Conclusions DPP-4 administration influences progression of IMH patients with DM, leading to a lower rate of aorta-related adverse events, aorta-related mortality, and reinterventions.