bluuebunny/crossref_metadata_2025 huggingface dataset:
The Son as a Torn Veil: The Mysteries of Jesus According to J. Ratzinger-Benedict XVI
Authors: Szymik Jerzy
Published: March 2021

J. Ratzinger-Benedict XVI relates theological cognition to following Jesus and going in His footsteps. He emphasizes the inseparable, mutual, servant-like relationship between academic theology and Christian praxis, Christological hermeneutics with the existential basis of faith. Intellectual and spiritual understanding of the mystery of Jesus depends on intimacy with Him and grows on this path: only the Son can show the Father because he knows Him in a way that defines his existence as the Son. The eternal inter-Trinitarian conversation with the Father – the prayer of the Son, His sonship-obedience – finds its corporal expression in history, and the humanity of Jesus, whose culmination is the cross, remains His prayer. The earthly life, and finally the Passover of Jesus, introduces into the human, vague concept of God the experience of the loving Father, thus making the course of history definitively meaningful and fulfilling, and the faith legitimate. Ratzinger defends Christology as a conceptual understanding of the truth of the Gospel, the depth and integrity of which Christology guards and to which it refers. Disregarding in faith the cognitive achievements and heritage of systematic theology leads to depriving faith of its most important contents, without which it starts to look in the dark for justifications which are subjective as well as fuzzy.
Fraternity in the Teaching of Pope Francis
Authors: Kućko Wojciech
Published: March 2021

The time of the coronavirus pandemic and the COVID-19 disease was an opportunity to ask anew many questions concerning interpersonal relations. In this context, Pope Francis tries to take up the therapy of fraternity in order to effectively and consistently contrast the “globalization of indifference” with the “globalization of fraternity and solidarity.” The aim of this article is to show the essence of fraternity in the teaching of Pope Francis (before the publication of papal encyclical letter Fratelli tutti about fraternity) in the context of the teaching of the Catholic Church. The article presents the biblical roots of fraternity as well as its inclinations in the Magisterium of the Second Vatican Council and subsequent popes. The reinterpretation of the term “fraternity” in Francis’ thought includes: the “mysticism of the fraternity,” its inter-religious and social character, its global fraternity on the level of bioethics and ecology, and its connection to the “theory of contradictions” (Germ.: Gegensatz), which the Pope took from R. Guardini.
Análise da folksonomia em grupos colaborativos do Passei Direto
Authors: Oliveira Jéssica Pereira de , Pinho Fabio Assis
Published: March 2021

Este artigo é sobre a folksonomia como uma ferramenta que contribui para as atividades colaborativas de grupos de usuários na rede social acadêmica Passei Direto, com o objetivo de analisar a folksonomia como ferramenta de apoio em grupos colaborativos nessa rede social, por meio de estudo de caso holístico e exploratório, sendo realizada observação direta intensiva. A justificativa baseou-se na necessidade de compreender a potencialidade das atividades cooperativas e a solução das necessidades informacionais. Concluiu-se que a folksonomia é uma ferramenta de apoio em grupos colaborativos no Passei Direto, onde os usuários, no uso de tags em práticas de indexação, visam a enriquecer e ampliar as possibilidades de acesso às informações. No entanto, apesar de representar uma ferramenta de forte cunho colaborativo, a folksonomia também deixa lacunas no tocante à recuperação da informação, dada a falta de padronização e controle dessa ferramenta, embora essas características façam parte da sua essência.
Análise do discurso
Authors: Mello Mariana Rodrigues Gomes de , Valentim Marta Lígia Pomim
Published: March 2021

A linguagem é mais que a palavra escrita ou falada, é a direção do pensamento no contato com o contexto histórico-social no qual se está inserido. O discurso se apresenta enquanto mediação entre pessoas e realidades. A AD se apresenta como um constructo teórico-metodológico que possibilita averiguar construções ideológicas e efeitos de sentido do discurso em diferentes contextos, propiciando um olhar ampliado sobre a realidade. Objetiva-se inter-relacionar aspectos epistemológicos de Foucault e Heidegger, que possam servir como aportes ao método Análise do Discurso, e refletir sobre uma estrutura que possa ser aplicada nas pesquisas da área de CI. Para tanto, propõe-se o uso da Revisão Sistemática da Literatura (RSL) enquanto técnica, a fim de subsidiar uma apresentação mais concreta referente a aplicação da AD no campo da CI. Metodologicamente trata-se de um estudo exploratório traçado na inter-relação entre questões da Filosofia da Linguagem e aspectos metodológicos e epistemológicos da Ciência da Informação e para tanto, buscou-se a revisão da literatura de ambos os domínios. Ainda há uma certa relutância do uso da AD na CI por sua forma mais teórica, ou seja, sem um procedimento preestabelecido, como se verifica em outros métodos, tais como a Análise do Conteúdo que possibilita a análise categorial, a análise de avaliação, a análise de enunciação, a análise proposicional, entre outras.  O objetivo da AD não é estabelecer se um discurso é verdadeiro ou falso, mas sim os efeitos de sentidos e as questões subliminares. Portanto, no discurso construído com bases em preconceitos, por exemplo, serão reveladas as fragilidades inerentes àquela construção. Por outro lado, em um texto reflexivo, a tendência é que por meio da aplicação da AD, sejam reveladas toda solidez das ideias e estruturas. Assim, verifica-se a grande contribuição que AD pode aferir à CI e como Foucault e Heidegger podem ser imprescindíveis para compor o arcabouço teórico da AD, dependendo dos objetivos da pesquisa.
Micro Composite Palmitoylethanolamide/Rutin Reduces Vascular Injury through Modulation of the Nrf2/HO−1 and NF-kB Pathways
Authors: Fusco Roberta , Siracusa Rosalba , Gugliandolo Enrico , Peritore Alessio Filippo , D’Amico Ramona , Cordaro Marika , Crupi Rosalia , Impellizzeri Daniela , Gomiero Chiara , Cuzzocrea Salvatore , Di Paola Rosanna
Published: March 2021

Background:

Vascular remodeling processes induced by acute and chronic injuries
are characterized by inflammation and oxidative stress. In arteriosclerosis, atherosclerosis,
and restenosis, the progression of neointimal hyperplasia is a key event of vascular
damage.

Objective:

Our study was aimed to investigate the inflammation and oxidative stress development
during vascular impairment and the potential efficacy of treatment of new micro
composite N-palmitoylethanolamine/Rutin at a ratio of 1:1 (PEA/RUT). The anti-inflammatory
effects of Palmitoylethanolamide (PEA) are well known. Rutin has important
pharmacological actions, including antioxidant and vasoprotective.

Methods:

As a model of vascular injury, we used the complete ligature of the left carotid
artery for fourteen days and administered PEA/RUT at the dose of 10 mg/Kg.

Results:

This study demonstrated that after fourteen days of carotid ligation, there is a
substantial structural change in the vessel morphology, with inflammatory cell infiltration
and reactive oxygen species production. PEA/RUT administration reduced change in
vascular morphology, cytokines like monocyte chemoattractant protein-1 (MCP-1) and
adhesion molecules expression like intercellular adhesion molecules-1 (ICAM-1), proinflammatory
cytokines production (IL-1 β, IL-6 and TNF- α), oxidative and nitrosative
stress (nitrotyrosine and PARP expression and NRF2 pathway).

Conclusions:

Our data clearly demonstrate the beneficial effect of PEA/RUT administration
in reducing inflammation, oxidative stress, and vascular damage.
Nanomedical Applications of Amphiphilic Dendrimeric Micelles
Authors: Rodríguez-Acosta Guillermo Leobardo , Hernández-Montalbán Carlos , Vega-Razo María Fernanda Sabrina , Castillo-Rodríguez Irving Osiel , Martínez-García Marcos
Published: March 2021

:

In recent years, polymeric materials with the ability to self-assemble into micelles
have been increasingly investigated for application in various fields, mainly in
biomedicine. Micellar morphology is interesting in the field of drug transport and delivery
since micelles can encapsulate hydrophobic molecules in their nucleus, have active
molecules in their outer layer, and due to their nanometric size, can take advantage of the
enhanced permeability and retention (EPR) effect, prolong the time in circulation and
avoid renal clearance. In addition, nanobioactive molecules (joined in covalent form or
by host-host interaction), such as drugs, bioimaging molecules, targeting ligands, “crosslinkable”
molecules or bonds, sensitive to internal or external stimuli, can be incorporated
into them and showed better activity as anticancer agents, siRNA delivery agents as
well as antiviral and antiparasitic compounds.

:

The present work is a review of the information published, which is the most important
about the synthesis and biological importance of the confined multivalent cooperation
and the ability to modify the dendritic structure, provide the versatility to create and improve
the amphiphiles used in the micellar supramolecular field. The most studied structures
are the hybrid copolymers formed by the combination of linear polymers and dendrons.
However, small dendritic molecules that do not involve linear polymers have also
been developed, such as Janus dendrimers, facial dendrons, and dendritic amphiphiles
with only one dendron. Amphiphilic dendrimer micelles have achieved efficient and
promising results, both in in vitro and in vivo tests, which encourage their research for future
application in nanotherapies.
COVID-19 in Pediatrics: A Diagnostic Challenge
Authors: Mohamed Amal A. , Mohamed Nouran , Abd-Elsalam Sherief , ElSadek Sanaa Mohammed , Ahmed Hoda Hegazy , Taha Hams Ahmed , Mohamed Gamil K. , Soliman Doaa Refaey
Published: March 2021

Most pediatric patients with COVID-19 described in the literature have unusual or mild
respiratory symptoms. Fever is usually a prominent feature. Cough is described frequently. Less
common are sore throat, headache, productive cough, nausea, and diarrhea. Some studies estimate
that children made up about 2% of the affected population. Nearly 1.2% of infected children need
hospital treatment and some children require mechanical ventilation. The immune system in children
is in its development stage, therefore the immune response to pathogens is different from
adults.
Intrathyroidal Ectopic Thymus and Sonoelastographic Findings
Authors: Guneyli Serkan , Aygun Murat Serhat , Taskin Orhun Cig , Sagtas Ergin , Colakoglu Bulent
Published: March 2021

Background:

Intrathyroidal ectopic thymus (IET) can be misdiagnosed as thyroid nodules.

Purpose:

The purpose of this study is to evaluate the sonoelastographic findings of IET in pediatric
population.

Methods:

Twelve children who had been examined with ultrasound (US) and strain elastography
between December 2012 and December 2019 were included in this retrospective study. The patients’
demographics and ultrasonographic findings, including the location, margin, shape, diameters,
volume, structure, vascularity, and elastography values of the lesions were evaluated.

Results:

Twelve lesions were detected in 12 asymptomatic patients (3 females and 9 males) with a
mean age of 4.67 ± 2.27 years. The most common location of the IET was in posterior part and middle
third of thyroid, and the most common appearance on US was a well-defined, ovoid-shaped,
and predominantly hypoechoic solid lesion with punctate/linear branching hyperechogenities. The
lesions were mostly hypovascular on Doppler US. The mean strain ratio on elastography was
found to be 1.10 ± 0.04. In the follow-up of 7 patients with available information, there was no significant
change in size or appearance of IET on US.

Conclusion:

IET should be considered in the differential diagnosis of the lesions within the thyroid.
The first step to accurately diagnose an IET is to consider it in the differential diagnosis. In addition
to US, strain elastography findings can be used to distinguish IETs from papillary thyroid
cancers which can have similar US appearance, and help avoid unnecessary biopsies.
Antiplasmodial and Cytotoxic Activities of two Euphorbiaceae Family
Plants, Euphorbia hirta and Euphorbia thymifolia
Authors: Vadalia Jigna , Sanandia Jalpa , Bhatt Vaibhav , Sheth Navin
Published: March 2021

Background:

Malaria is a major disease in developing countries, and the main issue is
its control of resistance against all available anti-malarial drugs. Our aim was to find affordable
therapy for this global problem. The present study was conducted to evaluate the antiplasmodial
and cytotoxic activities of Euphorbia hirta and Euphorbia thymifolia.

Methods:

The antiplasmodial activity was evaluated against chloroquine-sensitive (MRC-2), and
chloroquine-resistant (RKL-9) strains of Plasmodium falciparum through schizont maturation inhibition
and Plasmodium lactate dehydrogenase (PfLDH) activity assays. The cytotoxicity was performed
by MTT assay on the Huh7 liver carcinoma cell line.

Results:

IC50 for PfLDH activity of E. hirta and E. thymifolia methanol extract against P. faciparum
MRC-2 strain was 9.6 and 12.6 μg/mL, respectively, and against P. faciparum RKL-9 strain
was 10.2 and 11.56 μg/mL, respectively. Methanol extract of E. thymifolia showed lower IC50
(19.3 μg/mL) than methanol extract of E. hirta (24.7 μg/mL) in the MTT assay against Huh7 cell
line.

Conclusion:

Both the plant methanol extracts showed a two-fold lower cytotoxic activity against
hepatocyte-derived carcinoma cell line (Huh7) compared to in vitro inhibitory activity against P.
falciparum strains (MRC-2 and RKL-9).
Permeation of Hydroxypropyl-Beta-Cyclodextrin and Its Inclusion Complex Through Mouse Small Intestine Determined by Spectrophotometry
Authors: Yang Ping , Luo Jinhua , Yan Shuo , Li Xiaohong , Yao Qian
Published: March 2021

Background:

Cyclodextrins (CDs) are commonly used host molecules of inclusion complex.
However, due to the lack of a sensitive determination method, the absorption process of CDs
remains unclear.

Objective:

In this study, an oleuropein (OL) inclusion complex employing hydroxylpropyl-betacyclodextrin
(HP-beta-CD) as host molecules was prepared and the formation of inclusion complex
was ascertained by FT-IR and DSC. Spectrophotometry was established for the determination of
HP-beta-CD, based on the fact that the absorbance of phenolphthalein (PP) decreased in the presence
of HP-beta-CD.

Methods:

The assay conditions were optimized to augment the method sensitivity. Molecular docking
was employed to verify the strong interaction between PP and HP-beta-CD. The permeation
process of free HP-beta-CD, HP-beta-CD of OL inclusion complex, free OL, and OL in the inclusion
complex, was examined using an in vitro mouse small intestine model.

Results:

Though HP-beta-CD possessed a hydrophilic outside shell, it could permeate through the
mouse small intestine quickly with a cumulative permeating amount of over 90% in 2 h. Free HPbeta-
CD, the host molecule HP-beta-CD, and guest molecule OL of the inclusion complex exhibited
consistent permeating profiles across the mouse small intestine.

Conclusion:

The approach for the determination of HP-beta-CD was accurate and precise
(%RSD=2.98).
Construction and Validation of Prognostic Markers of Liver Cancer Based on Autophagy Genes
Authors: Zhou Dawei , Wan Juncheng , Luo Jiang
Published: March 2021

Background:

Liver cancer is one of the most common diseases in the world. At present, the
mechanism of autophagy genes in liver cancer is not very clear. Therefore, it is meaningful to study the role and
the prognostic value of autophagy genes in liver cancer.

Objective:

The purpose of this study is to conduct a bioinformatics analysis of autophagy genes related to
primary liver cancer for establishing a prognostic model of primary liver cancer based on autophagy genes.

Methods:

We identified autophagy genes related to the prognosis of liver cancer through bioinformatics methods.

Results:

Through difference analysis, 31 differential autophagy genes were screened out and then analyzed by
GO and KEGG analysis. At the same time, we built a PPI network. For optimizing the evaluation of the
prognosis of liver cancer patients, we integrated multiple autophagy genes, after which a prognostic model was
established. By using univariate cox regression analysis, 15 autophagy genes related to prognosis were screened
out. Then we included these 15 genes into the Least Absolute Shrinkage and Selection Operator (LASSO) and
performed a multi-factor cox regression analysis on the 9 selected genes for constructing a prognostic model. The
risk score of each patient, who participated in the establishing of the model, was calculated based on 4 genes
(BIRC5, HSP8, SQSTM1, and TMEM74). Then the patients were divided into high-risk groups and low-risk
groups. In the multivariate cox regression analysis, the risk score was assessed by the independent prognostic
factors (HR = 1.872, 95% CI = 1.544 - 2.196, p < 0.001). Survival analysis showed that the survival time of the
low-risk group was significantly longer than that of the high-risk group. By combining clinical characteristics
and autophagy genes, we constructed a nomogram for predicting the prognosis. The external dataset GSE14520
proved that the nomogram has a good prediction for individual patients with primary liver cancer.

Conclusion:

This study provided potential autophagy-related markers for liver cancer patients to predict their
prognosis and reveal part of the molecular mechanism of liver cancer autophagy. At the same time, certain gene
pathways and protein pathways related to autophagy may provide some inspiration for the development of anticancer
drugs.
Microwave-assisted Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Using Acid-Functionalized Mesoporous Polymer
Authors: Changmai Bishwajit , Rajkumari Kalyani , Das Diparjun , Rokhum Lalthazuala
Published: March 2021

Background:

In recent years, 3,4-dihydro-pyrimidin-2-(1H)-ones (DHPMs) have attracted
significant attention due to their diverse range of biological properties such as antibacterial,
antiviral, antitumor, anti-inflammatory, calcium channel blocking activities, etc. Taking into account,
in this present work, a polymer-based solid acid catalyst is employed for the microwaveassisted
synthesis of DHPMs.

Introduction:

Multicomponent reactions (MCRs) are attracting utmost attention as they promote
the formation of several bonds in a single process with diverse advantages. Biginelli reaction is the
top-ranked example of MCR for the synthesis of dihydropyrimidinones (DHPMs). Solid catalysts
are considered a significant tool for MCRs as they are non-toxic, easy to handle, reusable, and
have high selectivity and easy separation process.

Methods:

DHPMs synthesis was carried out using acid-functionalized mesoporous polymer
(AFMP) catalyst under microwave irradiation and solvent-free condition.

Results:

AFMP showed good to excellent DHPMs yield (89-98%) under the optimized reaction
conditions: 1:1:1.2 molar ratio of aldehyde/ethyl acetoacetate/urea, catalyst loading of 6 wt.%
(with respect to aldehyde), the temperature of 80 °C and microwave power of 500 W.

Conclusion:

We have successfully utilized microwave-assisted AFMP catalyst for the synthesis of
DHPMs under solvent-free conditions via the Biginelli approach. The catalyst is recyclable and
reusable in up to 5 consecutive reaction cycles with no significant loss in catalytic activity.
Graphene Versus Coronavirus: A Study of the Graphene Properties that Can Help Combat Coronavirus
Authors: Guerra T. , Assis I. O. , Guerra A. B.
Published: March 2021

:

New and fascinating physical, chemical and biological phenomena arise in ultra-small
materials, such as graphene. Graphene is a single layer formed only for carbon atoms, super-strong,
200 times stronger than steel and as much as 6 times lighter. It also has a high elasticity and density.
Furthermore, it seems to be impermeable to almost everything, but allows the passage of water
and air. Due to its versatility, modern and urgent applications arise every day, one of the most necessary,
currently, is the control of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the virus responsible for the novel coronavirus disease (COVID-19), which has dimensions
around 100 nm and has caused a worldwide public health emergency. Different ways to prevent
coronavirus contagion has proposed and one of them is the use of masks. Here, we investigated
some properties of graphene that can help combat COVID-19. A scale appropriate for comparison
shows that the spatial dimension of a virus is much larger than the graphene sheet, making it a
great candidate for manufacturing face masks, filters and respirators. We also make use of firstprinciples
calculations, based on the density functional theory (DFT), to investigate the interaction
between graphene and a water molecule. We observed that the water molecule undergoes a repulsion
force when it is very close to the graphene sheet. The hydrophobicity of graphene can be important
to prevent the face mask that doesn’t get wet when you breathe with it.
Comparing the Efficacies of Telemedicine and Standard Prenatal Care on Blood Glucose Control in Women With Gestational Diabetes Mellitus: Randomized Controlled Trial
Authors: Tian Ying , Zhang Suhan , Huang Feiling , Ma Liangkun
Published: March 2021

Background

Gestational diabetes mellitus (GDM) can usually be well controlled by health education and lifestyle management, resulting in better pregnancy outcomes. However, standard clinical prenatal care, which consists of clinic visits every 2 weeks, may not provide sufficient management for women with GDM. Telemedicine demonstrates a potential to fill this gap.

Objective

The objective of this study was to investigate whether health education and lifestyle management delivered through a WeChat group chat was more effective in controlling blood glucose (BG) than standard clinical prenatal care among women with GDM.

Methods

In this multicenter randomized controlled trial, women with GDM diagnosed by an oral glucose tolerance test between 23 and 30 (+6) gestational weeks were randomized to a WeChat group chat–based BG management group or a routine clinical prenatal care group. The primary outcome was the change in the glycemic qualification rate during the follow-up period in both groups. The secondary outcomes were pregnancy outcomes.

Results

A total of 309 women with GDM participated in the trial, with 162 women randomized to the control group and 147 to the intervention group. No significant differences in baseline characteristics were found between the control and intervention groups. Participants were further divided into 4 groups according to gestational weeks at enrollment for further analysis. The glycemic qualification rate of the intervention group was higher than that of the control group at nearly all time points in Groups 1 to 3, among which 3 time points reached statistical significance: Group 1 at T3 (54.8% vs 83.3%) and Group 2 at T3 (62.5% vs 80.0%) and T7 (75.0% vs 100%). The glycemic qualification rate gradually increased as gestational weeks progressed in both groups, regardless of the intervention method. None of the pregnancy outcomes measured, including delivery mode, premature rupture of the membranes, preterm birth, infant's birth weight, and postpartum hemorrhage, were significantly different between the control and intervention groups.

Conclusions

This multicenter randomized controlled trial that assessed women with noninsulin-dependent GDM demonstrated that additional instant messaging platforms, such as WeChat, used for health education and lifestyle intervention in China tend to be more effective for BG control than standard clinical prenatal care alone.

Trial Registration

ClinicalTrials.gov NCT03748576; https://clinicaltrials.gov/ct2/show/NCT03748576
A Framework (SOCRATex) for Hierarchical Annotation of Unstructured Electronic Health Records and Integration Into a Standardized Medical Database: Development and Usability Study (Preprint)
Authors: Park Jimyung , You Seng Chan , Jeong Eugene , Weng Chunhua , Park Dongsu , Roh Jin , Lee Dong Yun , Cheong Jae Youn , Choi Jin Wook , Kang Mira , Park Rae Woong
Published: March 2021

BACKGROUND

Although electronic health records (EHRs) have been widely used in secondary assessments, clinical documents are relatively less utilized owing to the lack of standardized clinical text frameworks across different institutions.

OBJECTIVE

This study aimed to develop a framework for processing unstructured clinical documents of EHRs and integration with standardized structured data.

METHODS

We developed a framework known as Staged Optimization of Curation, Regularization, and Annotation of clinical text (SOCRATex). SOCRATex has the following four aspects: (1) extracting clinical notes for the target population and preprocessing the data, (2) defining the annotation schema with a hierarchical structure, (3) performing document-level hierarchical annotation using the annotation schema, and (4) indexing annotations for a search engine system. To test the usability of the proposed framework, proof-of-concept studies were performed on EHRs. We defined three distinctive patient groups and extracted their clinical documents (ie, pathology reports, radiology reports, and admission notes). The documents were annotated and integrated into the Observational Medical Outcomes Partnership (OMOP)-common data model (CDM) database. The annotations were used for creating Cox proportional hazard models with different settings of clinical analyses to measure (1) all-cause mortality, (2) thyroid cancer recurrence, and (3) 30-day hospital readmission.

RESULTS

Overall, 1055 clinical documents of 953 patients were extracted and annotated using the defined annotation schemas. The generated annotations were indexed into an unstructured textual data repository. Using the annotations of pathology reports, we identified that node metastasis and lymphovascular tumor invasion were associated with all-cause mortality among colon and rectum cancer patients (both P=.02). The other analyses involving measuring thyroid cancer recurrence using radiology reports and 30-day hospital readmission using admission notes in depressive disorder patients also showed results consistent with previous findings.

CONCLUSIONS

We propose a framework for hierarchical annotation of textual data and integration into a standardized OMOP-CDM medical database. The proof-of-concept studies demonstrated that our framework can effectively process and integrate diverse clinical documents with standardized structured data for clinical research.
Model Pengembangan Pariwisata Kreatif untuk Mencapai Keberlanjutan di Desa Wisata Kasongan
Authors: Swesti Woro , Soeprihanto John , Widiyastuti Dyah
Published: March 2021

Seiring dengan perkembangan pariwisata khususnya pariwisata budaya yang tidak hanya menempatkan wisatawan sebagai “penonton” atau penikmat saja, maka pengembangan Desa Wisata Kasongan sebagai tujuan wisata pariwisata kreatif diharapkan dapat memaksimalkan potensi wisata budaya melalui kekhasan kerajinan dimiliki. Sayangnya, Desa Wisata Kasongan saat ini dominan pada upaya memenuhi pasokan industri gerabah sebagai komoditas perdagangan daripada tujuan pengembangan pariwisata. Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus (case study research). Teknik pengumpulan data dilakukan dengan wawancara, observasi, dan studi pustaka, dengan model analisis data kualitatif Spradley. Hasil penelitian menunjukan, tahap perkembangan pariwisata di Kasongan saat ini menurut konsep Tourism Area Life Cycle berada pada tahap kedua yaitu involvement (fase pelibatan). Untuk meningkatkan perkembangan pariwisata di Desa Wisata Kasongan pada tahap ketiga (development phase), maka penulis mengusulkan model pengembangan pariwisata kreatif. Model pengembangan pariwisata kreatif di Desa Wisata Kasongan merupakan gabungan kondisi faktor internal dan eksternal yang memerlukan campur tangan dari institusi atau lembaga yang memiliki perhatian serius pada pariwisata. Model pengembangan pariwisata kreatif di Desa Wisata Kasongan merupakan model pengembangan yang berdasarkan pada pola bisnis industri kreatif subsektor kerajinan yang berkelanjutan, dimana pariwisata berperan memberikan nilai tambah, yang nilai komersialnya ternyata mampu melebihi bisnis/industri kerajinan itu sendiri. Penerapan konsep pengembangan pariwisata kreatif, pada akhirnya diharapkan mampu mendorong terciptanya keberlanjutan dalam pembangunan pariwisata di Desa Wisata Kasongan dari sisi sosial budaya, lingkungan, dan ekonomi.
Hibriditas, Nation, dan Aspek Nostalgis Representasi Pascakolonial dalam Lirik Lagu-Lagu Jawa Suriname
Authors: Sulistyo Hary , Binangun Panji Satrio , Sartika Endang
Published: March 2021

Tulisan ini membahas representasi hibriditas identitas dan kebudayaan yang tercermin dalam lirik-lirik lagu berbahasa Jawa (suku di Indonesia) pada masyarakat Jawa yang di hidup Suriname (Amerika Selatan). Budaya hybrid tersebut umum ditemukan di kalangan masyarakat diaspora memiliki aspek nostalgis yang merasa bagian dari leluhurnya. Mengacu pada teori pasca-kolonial Bhaba (1994), tulisan ini mununjukkan bagaimana lirik lagu yang latar budaya hybrid tidak hanya menghadirkan perpaduan kebudayaan tetapi juga gagasan nation yang baru. Metode penelitian ini adalah deskriptif kualitatif, dengan langkahlangkah penelitian meliputi pembacaan terhadap lirik lagu, pengkategorian aspek hibriditas dan deskripsinya, penjabaran konsepsi nation dan aspek nostalgis dengan dukungan data penelitian yang relevan. Hasil penelitian menunjukkan tiga manifestais hibriditas kebudayaan, yaitu: (1) hibriditas masyarakat Jawa Suriname yang memuat tiga kebudayaan asal usul Jawa, kolonialisme Barat, masyarakt multietnis Suriname, (2) identitas ganda Jawa dan Suriname dalam melalui aktivitas nostalgis mengenang leluhur, dan (3) gagasan nation baru yang dibentuk oleh kesadaran atas kehidupan baru dengan perjuangan hidup Suriname kekinian.
Development and Content Validity of a Patient-Reported Experience Measure for Home Dialysis
Authors: Rivara Matthew B. , Edwards Todd , Patrick Donald , Anderson Lisa , Himmelfarb Jonathan , Mehrotra Rajnish
Published: March 2021

Background and objectives

The population of patients with kidney failure in the United States using home dialysis modalities is growing rapidly. Unlike for in-center hemodialysis, there is no patient-reported experience measure for assessment of patient experience of care for peritoneal dialysis or home hemodialysis. We sought to develop and establish content validity of a patient-reported experience measure for patients undergoing home dialysis using a mixed methods multiple stakeholder approach.

Design, setting, participants, & measurements

We conducted a structured literature review, followed by concept elicitation focus groups and interviews among 65 participants, including 21 patients on home dialysis, 33 home dialysis nurses, three patient care partners, and eight nephrologists. We generated a list of candidate items for possible measure inclusion and conducted a national prioritization exercise among 91 patients on home dialysis and 39 providers using a web-based platform. We drafted the Home Dialysis Care Experience instrument and conducted cognitive debriefing interviews to evaluate item interpretability, order, and structure. We iteratively refined the measure on the basis of interview findings.

Results

The literature review and concept elicitation phases supported 15 domains of home dialysis care experience in six areas: communication and education of patients, concern and helpfulness of the care team, proficiency of the care team, patient-centered care, care coordination, and amenities and environment. Focus groups results showed that domains of highest importance for measure inclusion were patient education and communication, care coordination, and personalization of care. Prioritization exercise results confirmed focus group findings. Cognitive debriefing indicated that the final measure was easily understood and supported content validity.

Conclusions

The Home Dialysis Care Experience instrument is a 26-item patient-reported experience measure for use in peritoneal dialysis and home hemodialysis. The Home Dialysis Care Experience instrument represents the first rigorously developed and content-valid English-language instrument for assessment of patient-reported experience of care in home dialysis.
МНОГОУРОВНЕВЫЙ МЕМРИСТИВНЫЙ ЭЛЕМЕНТ НА БАЗЕ НАНОГРАНУЛИРОВАННОГО КОМПОЗИТА (COFEB)X(LINBO3)100-X С ТОНКОЙ ПРОСЛОЙКОЙ АМОРФНОГО LINBO3
Authors: Ситников А.В. , Бабкина И.В. , Калинин Ю.Е. , Никонов А.Е. , Копытин М.Н. , Никируи К.Э. , Ильясов А.И. , Черноглазов К.Ю. , Николаев С.Н. , Васильев А.Л. , Емельянов А.В. , Демин В.А. , Рыльков В.В.
Published: March 2021

Представлены результаты исследования эффекта резистивного переключения (РП) в структурах металл / нанокомпозит / металл (М/НК/М) на базе НК (CoFeB)x(LiNbO3)100-x. Показано, что структуры демонстрируют стабильные РП с характеристиками, необходимыми для построения нейроморфных вычислительных систем. Предложена качественная модель многоуровневого РП, основанная на многофиламентном механизме переключения. Продемонстрирована возможность использования НК-мемристоров в качестве синапсов на примере простых нейроморфных сетей.
ОСНОВНЫЕ ПОДХОДЫ К ПОВЫШЕНИЮ АВТОНОМНОСТИ КРУПНОРАЗМЕРНЫХ БЕСПИЛОТНЫХ АВИАЦИОННЫХ СИСТЕМ ДВОЙНОГО НАЗНАЧЕНИЯ
Authors: Федулин А.М. , Дрягин Д.М.
Published: March 2021

Предложена архитектура построения бортового вычислителя на основе комбинации специализированных процессоров и программно-математического аппарата, обеспечивающих решение задач повышения автономности БАС. Приведены результаты летных экспериментов по применению данного подхода для БАС «Орион-Э».
ПЕРЕХОДНЫЕ ПРОЦЕССЫ В МНОГОУРОВНЕВЫХ МЕМРИСТИВНЫХ СТРУКТУРАХ НА ОСНОВЕ КРИСТАЛЛОВ СЕЛЕНИДА ВИСМУТА
Authors: Зотов А.В. , Борисенко И.Ю. , Тулин В.А.
Published: March 2021

Исследовались переходные процессы резистивных переключений и возможность управления многоуровневыми мемристивными структурами на основе селенида висмута.
ФОРМИРОВАНИЕ ДИФФУЗИОННЫХ БАРЬЕРОВ В СИСТЕМЕ МЕДНОЙ МЕТАЛЛИЗАЦИИ В МЕТОДЕ GAP FILLING
Authors: Орлов А.А. , Резванов А.А. , Гвоздев В.А. , Кузнецов П.И. , Серегин Д.С. , Веселов А.А. , Блумберг Т. , Сузуки Т. , Морозов Е.Н.
Published: March 2021

В работе предлагается и исследуется материал AlN в качестве диффузионного барьера в методе gap filling для предотвращения диффузии меди в пористый диэлектрик через открытые концы проводников. Исследования свойств указанного барьера проводились методами растровой электронной микроскопии и электрофизическими методами. Получено, что при толщине AlN 6 нм не наблюдается атомарной диффузии меди в диэлектрик.
РАЗРАБОТКА ИНСТРУМЕНТА ДЛЯ ГЕНЕРАЦИИ БИБЛИОТЕКИ ТЕСТОВЫХ СТРУКТУР ДЛЯ ПРОВЕДЕНИЯ SMO
Authors: Сахащик У.А. , Соколова Е.В.
Published: March 2021

В данной работе представлен инструмент для генерации библиотеки тестовых ячеек для технологии 28 нм и ниже, а также проведено исследование данного набора на наличие запрещенных шагов - структур, конфигурация которых не позволяет получить необходимое окно процесса.
РЕАЛИЗАЦИЯ ФУНКЦИОНАЛЬНО ПОЛНОГО НАБОРА ЛОГИЧЕСКИХ ВЕНТИЛЕЙ НА ОСНОВЕ МЭМС
Authors: Соловьев А.А.
Published: March 2021

Представлены варианты исполнения логических вентилей функционально полного набора на основе микроэлектромеханических систем (МЭМС).
THE IMPACT OF SPORT GAMES EXERCISE PROGRAMS ON THE DEVELOPMENT OF SPECIFIC MOTOR ABILITIES IN ADOLESCENTS WITH INTELLECTUAL IMPAIRMENT
Authors: Pejčić Aleksandar , Kocić Miodrag
Published: March 2021

The aim of this study was to determine the effects of a sports games experimental program on improving specific motor abilities in adolescents with mental impairment. The study was conducted on a sample of 60 adolescents diagnosed with mild mental impairment, divided into two groups (experimental group EG, and control group CG) with an equal number of participants. The special program of sports games lasted for 12 weeks, with a weekly frequency of four times and a duration of 30 minutes per training. The participants of both groups were tested with the same variables within the specific motor skills for the sport of football and basketball. After a twelve-week experimental program of sports games, there were statistically significant improvements in the EG in the variables: SMFS, SMDR, SMCP with a statistical significance of r=0.000. The results of the ANOVA and MANOVA analyses indicated that after the application of the specific sports games program there was a statistically significant difference in the benefits for the EG compared to the CG, in the parameters of specific motor abilities with a statistical significance r=0.000 and the size of the impact. Based on these research results, it can be concluded that a specific exercise program conducted within twelve-week training of specifically dosed sports activities has significantly contributed the development of specific motor skills for football and basketball.
BODY HEIGHT AND LORDOTIC POSTURE IN PRESCHOOL CHILDREN
Authors: Bogdanović Zoran , Radenković Oliver , Kahrović Izet , Murić Benin , Špirtović Omer
Published: March 2021

The aim of this research is to determine the relation between body height and lordotic posture in preschool children. The survey was conducted on a sample of 149 participants (78 boys and 71 girls), aged 6 years (± 6 months), of an average body height (BH) of 121.94±10.29 cm, and the body mass 23.20±4.83kg in the city of Kragujevac (Serbia). To assess lordotic posture, the Spinal Mouse was used, and all values above 30˚ were treated as disorders in the lumbar region. In determining the size of the body, the Anthropometer by Martin is used, and the participants were divided into five groups by height. The existence and size of the correlation between the investigated areas was calculated by the use of the Pearson's chi-squared test and contingency coefficient as a measure of correlation. From the total sample, lortodic posture is present in 8.05 % of the participants, and in terms of gender the incidence of poor posture is equal. Lordotic posture is most pronounced in the group of boys and girls with the BH of 123.01-127.00 cm, followed by the group of girls with a BH of 121.51-123.00 cm. The lowest incidence of lordotic posture is determined in the groups with BH over 127.01 cm, and below 119 cm. The values of the Pearson's chi-squared test indicate a statistically significant correlation between lordotic posture and body height, with a significance 0.03.
SOCIODEMOGRAPHIC FACTORS AND LOW BACK PAIN IN MUNICIPALITY PHYSICAL ACTIVITY PROGRAMS FOR FEMALE PARTICIPANTS
Authors: Kosmas Ioannis , Georgiou Yannis , Marmara Eleni , Fotiou Aggeliki
Published: March 2021

The purpose of this study was to investigate the relationship between low back pain (LBP) and factors such as education level and years of work in 131 women aged 42±1.10 years, participating in the "Sports for All" municipal physical activity (PA) programs in Greece. To evaluate how PA affects the intensity of pain, the questionnaires “Grading the Severity of Chronic Pain-GSCP” and the “A Fear-Avoidance Beliefs Questionnaire-FABQ” were used. Analysis of Variation and the Tuckey post hoc tests calculated the difference among the questions of each of the questionnaires. Statistically significant differences were determined for three questions. Female participants with a medium or low level of education show less or no improvement in LBP. Concerning years of work, participants with fewer years of work suffer from higher LBP levels than the ones already working for longer time. Future studies of the relationship between specific PA programs, the content and nature of one’s job and the appearance of LBP are needed.
WINTER SPORTS ACTIVITIES COURSE FOR FUTURE KINESIOLOGISTS: TRENDS AND CHALLENGES
Authors: Plevnik Matej , Pišot Rado
Published: March 2021

The purpose of this paper is to present a model of winter sports activities course organized for bachelor students of kinesiology during 2010 through 2017 with the aim of acquiring two main competencies: (i) methods for and approaches to promoting an effective use of leisure time for individuals and groups through outdoor activities in winter time, and (ii) understanding the content, purpose and process of outdoor winter sports activities. A total of 70 kinesiology students (26 men and 43 women, age 21.5±2.3 years) collaborated in the survey (26.5 % response rate, N=264). Students classified their initial level of skiing knowledge as: 16 % beginners, 39 % average skiers, 23% good skiers and 22 % very good skiers. Students detected significant progress in their skiing knowledge (11% excellent progress, 63 % good/substantial progress and 26 % only slight progress). However, students did not differ in their progress according to their initial ski knowledge (χ2(9)=7.466, p<0.05). 21% of the students achieved the Ski Instructor qualification at the end of program. Ski progress plays an important role in the evaluation of satisfaction with the professional knowledge applicable to future work as a kinesiologist (χ2(2)=7.245; p=0.027) and the course performance from the view of acquired knowledge usefulness applicable to future work as a kinesiologist (χ2(2)=10.289; p=0.006). Results open up new possibilities for further improvements of the winter camp and its activities. Because of the sports field legislation change in 2017, new organizational adjustments are expected.
THE DEVELOPMENT OF MOTOR ABILITIES OF YOUNG ATHLETES AND GYMNASTS IN THE INITIAL PREPARATION PHASE
Authors: Dobrijević Slobodanka , Ćosić Marko , Kocić Pajić Sonja , Grujić Stevan , Moskovljević Lidija
Published: March 2021

The aim of this study is to determine the effect of sports gymnastics and athletics training on the development of athletes’ motor abilities in the initial preparation phase. The study was conducted on a sample of 81 girls and boys of about 9 years of age, who train athletics (N=34) and gymnastics (N=47). A total of 9 variables were observed, three to assess anthropometric characteristics (body height, body mass and the body mass index) and 6 to assess the participants’ motor abilities (explosive leg power, repetitive power, agility, power endurance, flexibility, cardiorespiratory endurance). The one-sample t-test was used to compare the results with mean values of the general population of the same age, whereas a univariate ANOVA was used to compare the results between the athletes and the gymnasts of different genders. The results show that the level of motor development in girls is significantly higher than in the general population, while in boys, significant progress was not registered in power endurance and cardiorespiratory endurance, regardless of the sport they are engaged in. Regardless of gender, gymnasts have better flexibility compared to athletes, while athletes have significantly higher explosive power and agility.
SELF-PERCEPTION OF SPORTING ABILITIES OF FEMALE ATHLETES WHEN COMPARED WITH SAME-SEX AND OPPOSITE-SEX ATHLETES
Authors: Trbojević Jovana , Petrović Jelica
Published: March 2021

The aim of this study is to determine how top-level female soccer and volleyball players, and young, cadet and junior female volleyball players view themselves, their abilities, and their specific motor skills for sport in relation to other female and male athletes. In Study 1, the sample consisted of 24 female top soccer and volleyball players of the highest sporting rank in Serbia. In Study 2, the sample consisted of 31 female cadet and junior volleyball players. They all filled out a brief questionnaire regarding self-perception about their sporting abilities, when compared with same-sex and opposite-sex athletes of the same rank, sport and age. The results of Study 1 show that female top soccer and volleyball players perceive themselves as less competent when compared with male athletes of the same sport and age (t(22)=5.97, p=.00). The results of Study 2 show that female cadet and junior volleyball players perceive themselves as less competent in Serve strength (t(29)=3.27, p=.030) and Physical endurance and strength (t(29)=2.52, p=.017) when compared with male volleyball players of the same age. The obtained results call for further examination of gender differences in perceived self-competence.
THE RELATIONSHIP BETWEEN BREAKFAST CONSUMPTION AND BASKETBALL SHOOTING PERFORMANCE
Authors: Čabarkapa Dimitrije , Fry Andrew C. , Deane Michael A. , Akers Jeremy D.
Published: March 2021

The purpose of this study is to explore a possible relationship between breakfast consumption and basketball shooting performance. Eighteen male subjects (height=191.5±10.1 cm, mass=93.8±12.1 kg, age=27.5±10.6 years) with considerable amount of basketball playing experience were divided into two groups, with (BF) and without (No-BF) four-day breakfast consumption in a three-week cross-over study design. Subjects completed free throw, 2-point, and 3-point shooting drills on the fourth day of each week. Food intake records were collected during each treatment phase. Paired sample t-tests were used to examine the difference in basketball shooting performance (free throw, 2-point, and 3-point drills) and dietary intake patterns (calories, carbohydrates, proteins, and fats) between BF and No-BF testing weeks. Cohen’s D effect sizes were calculated to determine the magnitude of the breakfast consumption as an experimental factor. The average amount of calories, carbohydrates, proteins, and fats that the subjects consumed during the breakfast omission week was significantly lower when compared to the breakfast consumption week. Even though the overall basketball shooting performance was improved during the breakfast consumption week, only the average free throw shooting accuracy revealed statistically significant results. However, the effect sizes for almost all the dependent variables exhibited small to moderate magnitudes. Considering that basketball players are always looking for ways to improve their shooting performance, a well-balanced diet with habitual breakfast consumption may be a beneficial method for individual and team performance enhancement, which can ultimately lead to increased chances of a successful game outcome.
RELIABILITY OF TESTS FOR SPEED AND AGILITY ASSESSMENT IN CADET BASKETBALL PLAYERS
Authors: Lukić Miloš , Petrović Adam , Ćopić Nemanja , Petronijević Svetlana , Jovanović Srećko
Published: March 2021

The aim of this research is to determine whether the Illinois test (IL), T-test (Tt), 4x5m Shuttle run (4x5m), 20 m Sprint (S20m), 10 m Sprint (S10m) are reliable tests in assessing the speed and agility of cadet basketball players. The strategy of this research involved a traditional quantitative approach to research with a correlation studies design. The total sample consisted of 38 male participants. The mean age of the participants was -AGE=16.03 years, body height-BH=183.5 cm; body mass-BM=74.1 kg; Body Mass Index-BMI=22.08 kg/m2. The most reliable agility test when performing without a ball is ILNB, while less reliable are TtNB and the 4x5mNB, both without a ball. A reliable test that is performed without a ball to assess the speed of a cadet basketball player is the S10mNB. On the other hand, all speed and agility tests when performed with a ball are reliable for testing cadet basketball players. The proposed speed and agility tests have proven to be reliable for cadet basketball players.