bluuebunny/crossref_metadata_2025 huggingface dataset:
Data Supplement from Natural Killer Cells Eradicate Galectin-1–Deficient Glioma in the Absence of Adaptive Immunity
Authors: Baker Gregory J. , Chockley Peter , Yadav Viveka Nand , Doherty Robert , Ritt Michael , Sivaramakrishnan Sivaraj , Castro Maria G. , Lowenstein Pedro R.
Published: April 2023

Description of additional methods and procedures used in the study.
Data Supplement from Neuronal Pentraxin 2 Supports Clear Cell Renal Cell Carcinoma by Activating the AMPA-Selective Glutamate Receptor-4
Authors: von Roemeling Christina A. , Radisky Derek C. , Marlow Laura A. , Cooper Simon J. , Grebe Stefan K. , Anastasiadis Panagiotis Z. , Tun Han W. , Copland John A.
Published: April 2023

Supplementary Figure Legends
Supplementary Materials and Methods from Host Deficiency in Caveolin-2 Inhibits Lung Carcinoma Tumor Growth by Impairing Tumor Angiogenesis
Authors: Liu Yajun , Jang Sungchan , Xie Leike , Sowa Grzegorz
Published: April 2023

Supplementary Materials and Methods. Generation of Cav-2 KO mice RNA isolation and analysis of specific gene expression by quantitative real time PCR References
Supp Table S15 from In Vivo Disruption of an Rb–E2F–Ezh2 Signaling Loop Causes Bladder Cancer
Authors: Santos Mirentxu , Martínez-Fernández Mónica , Dueñas Marta , García-Escudero Ramón , Alfaya Begoña , Villacampa Felipe , Saiz-Ladera Cristina , Costa Clotilde , Oteo Marta , Duarte José , Martínez Victor , Gómez-Rodriguez Ma José , Martín Ma Luisa , Fernández Manoli , Viatour Patrick , Morcillo Miguel A. , Sage Julien , Castellano Daniel , Rodriguez-Peralto Jose L. , de la Rosa Federico , Paramio Jesús M
Published: April 2023

Supp Table S15. Transcription factor analyzed by Chip Enrichment analysis of the downregulated genes in human recurrent bladder tumors.
Data Supplement from Armed Oncolytic Virus Enhances Immune Functions of Chimeric Antigen Receptor–Modified T Cells in Solid Tumors
Authors: Nishio Nobuhiro , Diaconu Iulia , Liu Hao , Cerullo Vincenzo , Caruana Ignazio , Hoyos Valentina , Bouchier-Hayes Lisa , Savoldo Barbara , Dotti Gianpietro
Published: April 2023

Supplementary Table S1. Chemokine production of NB cells
Supp Table S10 from In Vivo Disruption of an Rb–E2F–Ezh2 Signaling Loop Causes Bladder Cancer
Authors: Santos Mirentxu , Martínez-Fernández Mónica , Dueñas Marta , García-Escudero Ramón , Alfaya Begoña , Villacampa Felipe , Saiz-Ladera Cristina , Costa Clotilde , Oteo Marta , Duarte José , Martínez Victor , Gómez-Rodriguez Ma José , Martín Ma Luisa , Fernández Manoli , Viatour Patrick , Morcillo Miguel A. , Sage Julien , Castellano Daniel , Rodriguez-Peralto Jose L. , de la Rosa Federico , Paramio Jesús M
Published: April 2023

Supp Table S10. Dataset containing the list of upregulated and downregulated genes in human bladder tumors according to recurrence.
Supplemental Table from Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study
Authors: Fortner Renée T. , Schock Helena , Kaaks Rudolf , Lehtinen Matti , Pukkala Eero , Lakso Hans-Åke , Tanner Minna , Kallio Raija , Joensuu Heikki , Grankvist Kjell , Zeleniuch-Jacquotte Anne , Toniolo Paolo , Lundin Eva , Surcel Helja-Marja
Published: April 2023

Doubling of Circulating Endogenous Hormones and Breast Cancer Risk, by Time Between First Birth and Diagnosis and Age at Diagnosis: Finnish Maternity Cohort (n=3,480).
Data Supplement from Molecular Imaging with Bioluminescence and PET Reveals Viral Oncolysis Kinetics and Tumor Viability
Authors: Kuruppu Darshini , Brownell Anna-Liisa , Shah Khalid , Mahmood Umar , Tanabe Kenneth K.
Published: April 2023

Supplemental Figure 2: Tumor growth and viral replication kinetics imaged with dual bioluminescence S2A: MC26-Rluc flank tumor growth imaged with Rluc bioluminescence. S2B: The fate of MC26-Rluc tumors undergoing viral oncolysis imaged with Rluc bioluminescence. S2C: Rluc bioluminescence signal intensities (expressed as mean net intensity/area +/- SD) in the control and treated groups. S2D: Volumetric measurements in the control and virus treated groups obtained with caliper readings. Tumor volume is expressed as the mean +/- SD. S2E: Virus replication imaged with Fluc bioluminescence. S2F: Virus replication quantified with Fluc signal intensities (expressed as mean net intensity/area +/- SD) showed several peaks (arrows) in the curve as the signal intensity decreased over time.
Data Supplement from Armed Oncolytic Virus Enhances Immune Functions of Chimeric Antigen Receptor–Modified T Cells in Solid Tumors
Authors: Nishio Nobuhiro , Diaconu Iulia , Liu Hao , Cerullo Vincenzo , Caruana Ignazio , Hoyos Valentina , Bouchier-Hayes Lisa , Savoldo Barbara , Dotti Gianpietro
Published: April 2023

Supplementary Movie 1C. Ad5ÃŽ?24 and control T cells
Supplementary Table S1 from Phosphoinositide Protein Kinase PDPK1 Is a Crucial Cell Signaling Mediator in Multiple Myeloma
Authors: Chinen Yoshiaki , Kuroda Junya , Shimura Yuji , Nagoshi Hisao , Kiyota Miki , Yamamoto-Sugitani Mio , Mizutani Shinsuke , Sakamoto Natsumi , Ri Masaki , Kawata Eri , Kobayashi Tsutomu , Matsumoto Yosuke , Horiike Shigeo , Iida Shinsuke , Taniwaki Masafumi
Published: April 2023

Supplementary Table S1. Clinical information of patients whose myeloma cells were subjected to Western blotting and in vitro treatment with BX-912.
Supplementary Figure S3 from Phosphoinositide Protein Kinase PDPK1 Is a Crucial Cell Signaling Mediator in Multiple Myeloma
Authors: Chinen Yoshiaki , Kuroda Junya , Shimura Yuji , Nagoshi Hisao , Kiyota Miki , Yamamoto-Sugitani Mio , Mizutani Shinsuke , Sakamoto Natsumi , Ri Masaki , Kawata Eri , Kobayashi Tsutomu , Matsumoto Yosuke , Horiike Shigeo , Iida Shinsuke , Taniwaki Masafumi
Published: April 2023

Supplementary Figure S3. AMO-1 cells and NCI-H929 cells were co-cultured with HS-5 cells for 48 hours, and then were treated by BX-912 at its IC50s for 3 hours. The activities of PDPK1Ser241, RSK2Ser227 and AKTThr308 were examined by Western blotting. Ctl. indicates cells cultured without the co-culture.
Supplementary Figure S2 from Phosphoinositide Protein Kinase PDPK1 Is a Crucial Cell Signaling Mediator in Multiple Myeloma
Authors: Chinen Yoshiaki , Kuroda Junya , Shimura Yuji , Nagoshi Hisao , Kiyota Miki , Yamamoto-Sugitani Mio , Mizutani Shinsuke , Sakamoto Natsumi , Ri Masaki , Kawata Eri , Kobayashi Tsutomu , Matsumoto Yosuke , Horiike Shigeo , Iida Shinsuke , Taniwaki Masafumi
Published: April 2023

Supplementary Figure S2. A, DNA content was examined by propidium iodide (PI)-staining of formalin-fixed cells using flow cytometric analysis. The X-axis represents DNA content, and the Y-axis represents the relative cell numbers. AR-12 (AR) treatment reduced G1 population (light green fraction) and increased the subG1 fraction, a hallmark of apoptosis induction (indicated by arrow), in the myeloma AMO-1 and NCI-H929 cell lines. AMO-1 and NCI-H929 cells were treated with AR at their IC80 concentrations for 12 and 24 hours. B, AMO-1 and NCI-H929 cells were treated with AR at their IC80 concentrations for 6 to 12 hours, and were subjected to double staining for Annexin-V (X-axis) and PI (Y-axis). AR treatment caused the increase of cells undergoing early apoptosis (Annexin-V-positive/PI-negative fraction) first, and, then, resulted in the increase of cells undergoing late apoptosis (double positive for Annexin-V and PI) in both AMO-1 cells and NCI-H929 cells.
Supplemental Figure Legends from Homeoprotein Six2 Promotes Breast Cancer Metastasis via Transcriptional and Epigenetic Control of E-Cadherin Expression
Authors: Wang Chu-An , Drasin David , Pham Catherine , Jedlicka Paul , Zaberezhnyy Vadym , Guney Michelle , Li Howard , Nemenoff Raphael , Costello James C. , Tan Aik-Choon , Ford Heide L.
Published: April 2023

Supplemental Figure Legends. Legends for Supplemental Figures S1-S8. Also includes Supplemental Reference.
Supplementary Table S9 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

Simulation of tumor mutational heterogeneity. Estimates are for the minimum number of cell replications required for two randomly chosen cells to possess the number of mutational differences observed in paired cell lines at a greater than 99% probability. Data were simulated using fixed mutation probabilities of 10-8 per base per cell replication for non-hypermutated and 10-6 for hypermutated MSI-H tumors.
Supplemental Movie 4 from AXL Inhibition Sensitizes Mesenchymal Cancer Cells to Antimitotic Drugs
Authors: Wilson Catherine , Ye Xiaofen , Pham Thinh , Lin Eva , Chan Sara , McNamara Erin , Neve Richard M. , Belmont Lisa , Koeppen Hartmut , Yauch Robert L. , Ashkenazi Avi , Settleman Jeff
Published: April 2023

Timelapse movie of HeLa cells treated with docetaxel (3nM) in combination with R428 (1ÃŽÂ¼M).
Supplemental Movie 3 from AXL Inhibition Sensitizes Mesenchymal Cancer Cells to Antimitotic Drugs
Authors: Wilson Catherine , Ye Xiaofen , Pham Thinh , Lin Eva , Chan Sara , McNamara Erin , Neve Richard M. , Belmont Lisa , Koeppen Hartmut , Yauch Robert L. , Ashkenazi Avi , Settleman Jeff
Published: April 2023

Timelapse movie of HeLa cells treated with docetaxel (3nM).
Supplementary Table S4 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

Comparison of POLE mutation spectra between 9 NSHP and 15 non-NSHP CRC cell lines and TCGA-analyzed primary cancers.
Supplementary Table S2 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

Somatic mutations in protein-coding genes identified in 70 CRC cell lines using exome-capture sequencing.
Supplementary Table S1 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

CRC cell line details and major molecular hallmarks.
Supplemental Dataset 2 from AXL Inhibition Sensitizes Mesenchymal Cancer Cells to Antimitotic Drugs
Authors: Wilson Catherine , Ye Xiaofen , Pham Thinh , Lin Eva , Chan Sara , McNamara Erin , Neve Richard M. , Belmont Lisa , Koeppen Hartmut , Yauch Robert L. , Ashkenazi Avi , Settleman Jeff
Published: April 2023

Supplemental Dataset 2. Kinome profile with 1000nM R428
Supplementary Table 9 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

XLSX file - 9KB, Simulation of tumor mutational heterogeneity. Estimates are for the minimum number of cell replications required for two randomly chosen cells to possess the number of mutational differences observed in paired cell lines at a greater than 99% probability. Data were simulated using fixed mutation probabilities of 10-8 per base per cell replication for non-hypermutated and 10-6 for hypermutated MSI-H tumors.
Supplemental Dataset 1 from AXL Inhibition Sensitizes Mesenchymal Cancer Cells to Antimitotic Drugs
Authors: Wilson Catherine , Ye Xiaofen , Pham Thinh , Lin Eva , Chan Sara , McNamara Erin , Neve Richard M. , Belmont Lisa , Koeppen Hartmut , Yauch Robert L. , Ashkenazi Avi , Settleman Jeff
Published: April 2023

Supplemental Dataset 1. Expression of AXL, GAS6, Vimentin and E-Cadherin in 644 human cancer cell line using RNAseq technology.
Supplemental Table 1 and 2 from ERK Mutations Confer Resistance to Mitogen-Activated Protein Kinase Pathway Inhibitors
Authors: Goetz Eva M. , Ghandi Mahmoud , Treacy Daniel J. , Wagle Nikhil , Garraway Levi A.
Published: April 2023

Supplemental Table 1 and 2. Amino acid substitutions for each significantly mutated ERK1/2 nucleotide for the ERK inhibitor screen (Table 1) or the RAF/MEK inhibitor screen (Table 2) and the accompanying resistance phenotype.
Supplementary Table 5 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

XLSX file - 50KB, Significantly altered focal regions of chromosomal deletion or gain/amplification for 63 unique CRC cell lines and 213 TCGA-analyzed primary cancers stratified into non-hypermutated and hypermutated MSI-H cases. Minimal focal regions were deduced using OncoSNP v2.18 suite and GISTIC2.0.
Supplementary Table 3 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

XLSX file - 45KB, Sanger sequencing validation for mutations detected by exome-capture sequencing for 12 genes in 43 CRC cell lines. Genes comprised APC, CTNNB1, KRAS, BRAF, NRAS, PIK3CA, PTEN, SMAD2, SMAD3, SMAD4, FBXW7 and TP53. Cell lines included C32, C70, C80, C84, C99, C106, CACO2, COLO201, COLO205, COLO320-DM, COLO678, DLD1, HCA7, HCC2998, HCT8, HCT15, HCT116, HRA19, HT29, HT55, LIM1215, LIM1899, LIM2099, LIM2405, LIM2551, LOVO, LS174T, LS180, LS411, LS513, RKO, RW2982, RW7213, SW48, SW403, SW480, SW620, SW837, SW948, SW1116, SW1222, T84 and VACO4S.
Supplementary Figures S1-S2 from PAK1 Tyrosine Phosphorylation Is Required to Induce Epithelial–Mesenchymal Transition and Radioresistance in Lung Cancer Cells
Authors: Kim EunGi , Youn HyeSook , Kwon TaeWoo , Son Beomseok , Kang JiHoon , Yang Hee Jung , Seong Ki Moon , Kim Wanyeon , Youn BuHyun
Published: April 2023

The activity of an anti-pSer/Thr antibody and overexpression of each PAK1 construct after transient transfection were verified (S1); JAK2 phosphorylates PAK1 in irradiated NSCLC cells (S2).
Supplementary Table 1 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

XLSX file - 23KB, CRC cell line details and major molecular hallmarks.
Supplementary Methods from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

PDF file - 91KB
Data Supplement from Ubiquitin-like Protein FAT10 Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Modifying β-Catenin Degradation
Authors: Yuan Rongfa , Wang Kai , Hu Junwen , Yan Chen , Li Ming , Yu Xin , Liu Xiuxia , Lei Jun , Guo Wuhua , Wu Linquan , Hong Kui , Shao Jianghua
Published: April 2023

Supplementary Table S1. Summary of significantly differentially expressed genes in Huh-7-shFAT10 compared with Huh-7-shNC cells.
Supplementary Figure 1 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

PDF file - 137KB, Correlation between RNA-Seq and gene expression microarray data (Affymetrix U133 Plus2.0 Arrays) for six CRC cell lines analyzed in independent experiments. Genes with detectable expression on both platforms were considered, defined as RNA-Seq RPKM value >1 and microarray intensity > log2(100). r-values, Spearman's rank correlation coefficient.
Data Supplement from Ubiquitin-like Protein FAT10 Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Modifying β-Catenin Degradation
Authors: Yuan Rongfa , Wang Kai , Hu Junwen , Yan Chen , Li Ming , Yu Xin , Liu Xiuxia , Lei Jun , Guo Wuhua , Wu Linquan , Hong Kui , Shao Jianghua
Published: April 2023

Supplementary Table S2. Primers and shRNA target sequences.
Data Supplement from Ubiquitin-like Protein FAT10 Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Modifying β-Catenin Degradation
Authors: Yuan Rongfa , Wang Kai , Hu Junwen , Yan Chen , Li Ming , Yu Xin , Liu Xiuxia , Lei Jun , Guo Wuhua , Wu Linquan , Hong Kui , Shao Jianghua
Published: April 2023

Supplementary Table S3. Association of various factors with invasion and metastasis determined by logistic regression.
Data Supplement from Ubiquitin-like Protein FAT10 Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Modifying β-Catenin Degradation
Authors: Yuan Rongfa , Wang Kai , Hu Junwen , Yan Chen , Li Ming , Yu Xin , Liu Xiuxia , Lei Jun , Guo Wuhua , Wu Linquan , Hong Kui , Shao Jianghua
Published: April 2023

Supplementary Figure S4. Knockdown of FAT10 inhibits HOXB9 expression through the β-catenin/TCF4 pathway in Huh-7 cells.
Supplementary Figure 3 from The TGFβ–miR200–MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors
Authors: Izumchenko Evgeny , Chang Xiaofei , Michailidi Christina , Kagohara Luciane , Ravi Rajani , Paz Keren , Brait Mariana , Hoque Mohammad O. , Ling Shizhang , Bedi Atul , Sidransky David
Published: April 2023

PDF file - 127KB, Levels of Mig6 protein in the panel of 25 human cancer cell lines with known erlotinib resistance was identified by immunoblot analysis followed by densitometric quantification. The expression level of Mig6 was plotted against IC50 of corresponding cell line.
Supplementary Figure 1 from The TGFβ–miR200–MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors
Authors: Izumchenko Evgeny , Chang Xiaofei , Michailidi Christina , Kagohara Luciane , Ravi Rajani , Paz Keren , Brait Mariana , Hoque Mohammad O. , Ling Shizhang , Bedi Atul , Sidransky David
Published: April 2023

PDF file - 2120KB, FAK activity is significantly higher in erlotinib-resistant cells from lung and H and N origin. Total cell lysates were extracted from two pairs of lung (H358/H1703 and Calu3/Calu6) and two pairs of H and N (SCC-S/SCC-R and JHU011/JHU028) cancer cell lines and were subjected to immunoblot analysis with antibodies specific for phosphorylated and total FAK. Beta-actin was used a loading control.
Supplementary Figure S5 from STAT1 Drives Tumor Progression in Serous Papillary Endometrial Cancer
Authors: Kharma Budiman , Baba Tsukasa , Matsumura Noriomi , Kang Hyun Sook , Hamanishi Junzo , Murakami Ryusuke , McConechy Melissa M. , Leung Samuel , Yamaguchi Ken , Hosoe Yuko , Yoshioka Yumiko , Murphy Susan K. , Mandai Masaki , Hunstman David G. , Konishi Ikuo
Published: April 2023

Supplementary Figure S5. Significance of STAT1-MYC activity in tumorigenesis.
Supplementary Figure S4 from STAT1 Drives Tumor Progression in Serous Papillary Endometrial Cancer
Authors: Kharma Budiman , Baba Tsukasa , Matsumura Noriomi , Kang Hyun Sook , Hamanishi Junzo , Murakami Ryusuke , McConechy Melissa M. , Leung Samuel , Yamaguchi Ken , Hosoe Yuko , Yoshioka Yumiko , Murphy Susan K. , Mandai Masaki , Hunstman David G. , Konishi Ikuo
Published: April 2023

Supplementary Figure S4. Stable knockdown of STAT1 expression.
Supplementary Figure S2 from STAT1 Drives Tumor Progression in Serous Papillary Endometrial Cancer
Authors: Kharma Budiman , Baba Tsukasa , Matsumura Noriomi , Kang Hyun Sook , Hamanishi Junzo , Murakami Ryusuke , McConechy Melissa M. , Leung Samuel , Yamaguchi Ken , Hosoe Yuko , Yoshioka Yumiko , Murphy Susan K. , Mandai Masaki , Hunstman David G. , Konishi Ikuo
Published: April 2023

Supplementary Figure S2. Comparison of STAT1 mRNA expression among histological subtypes of endometrial cancers.
Supplementary Figure Legends from STAT1 Drives Tumor Progression in Serous Papillary Endometrial Cancer
Authors: Kharma Budiman , Baba Tsukasa , Matsumura Noriomi , Kang Hyun Sook , Hamanishi Junzo , Murakami Ryusuke , McConechy Melissa M. , Leung Samuel , Yamaguchi Ken , Hosoe Yuko , Yoshioka Yumiko , Murphy Susan K. , Mandai Masaki , Hunstman David G. , Konishi Ikuo
Published: April 2023

Supplementary Figure Legends. Legend for Supplementary Figures S1-S5.
Supplementary Table S3 from A Small-Molecule Modulator of the Tumor-Suppressor miR34a Inhibits the Growth of Hepatocellular Carcinoma
Authors: Xiao Zhangang , Li Chi Han , Chan Stephen L. , Xu Feiyue , Feng Lu , Wang Yan , Jiang Jian-Dong , Sung Joseph J.Y. , Cheng Christopher H.K. , Chen Yangchao
Published: April 2023

Supplementary Table S3. Growth inhibitory rates of Rubone on HepG2 xenografts.
Supplementary Figure 4 from Rapamycin Rescues ABT-737 Efficacy in Small Cell Lung Cancer
Authors: Gardner Eric E. , Connis Nick , Poirier John T. , Cope Leslie , Dobromilskaya Irina , Gallia Gary L. , Rudin Charles M. , Hann Christine L.
Published: April 2023

PDF file - 187KB, Supplemental Figure 4. Dose-dependent effects of rapamycin and ABT-737 on LX33 PDXs.
Supplementary Table S1 from A Small-Molecule Modulator of the Tumor-Suppressor miR34a Inhibits the Growth of Hepatocellular Carcinoma
Authors: Xiao Zhangang , Li Chi Han , Chan Stephen L. , Xu Feiyue , Feng Lu , Wang Yan , Jiang Jian-Dong , Sung Joseph J.Y. , Cheng Christopher H.K. , Chen Yangchao
Published: April 2023

Supplementary Table S1. Primer sequences used for qRT-PCR.
Supplementary Figure 3 from Rapamycin Rescues ABT-737 Efficacy in Small Cell Lung Cancer
Authors: Gardner Eric E. , Connis Nick , Poirier John T. , Cope Leslie , Dobromilskaya Irina , Gallia Gary L. , Rudin Charles M. , Hann Christine L.
Published: April 2023

PDF file - 399KB, Supplemental Figure 3. SCLC PDXs and cell lines express mTOR pathway components and the combination of ABT-737 and rapamycin is well tolerated in PDX-bearing mice.
Data Supplement from Definition of PKC-α, CDK6, and MET as Therapeutic Targets in Triple-Negative Breast Cancer
Authors: Hsu Yi-Hsin , Yao Jun , Chan Li-Chuan , Wu Ting-Jung , Hsu Jennifer L. , Fang Yueh-Fu , Wei Yongkun , Wu Yun , Huang Wen-Chien , Liu Chien-Liang , Chang Yuan-Ching , Wang Ming-Yang , Li Chia-Wei , Shen Jia , Chen Mei-Kuang , Sahin Aysegul A. , Sood Anil , Mills Gordon B. , Yu Dihua , Hortobagyi Gabriel N. , Hung Mien-Chie
Published: April 2023

Supplementary Figure S1. The mRNA expression of MAP4K5, TRIO, EPHA4, DGKA and MAPK7 in TNBC cells Supplementary Figure S2. Inhibition of PKC-alpha, MET, and CDK6 reduced stem cell-like population.
Supplementary Figures and Tables from PCTAIRE1 Phosphorylates p27 and Regulates Mitosis in Cancer Cells
Authors: Yanagi Teruki , Krajewska Maryla , Matsuzawa Shu-ichi , Reed John C.
Published: April 2023

Supplementary Figures and Tables. Supplementary Fig. S1. Knockdown of PCTAIRE1 in PPC1 cells. Supplementary Fig. S2. Knockdown of PCTAIRE1 inhibits growth of Du145, MDA-MB-468 and HeLa cells. Supplementary Fig. S3. PCTAIRE1 regulates centrosome dynamics. Supplementary Fig. S4. PCTAIRE1 phosphorylates p27 at Ser10. Supplementary Fig. S5. PCTAIRE1 knockdown leads to accumulation of p27. Supplementary Fig. S6. Apoptosis induced by PCTAIRE1 knockdown, and subcellular localization of Eg5 in PCTAIRE1 knockdown cancer cells. Supplementary Fig. S7. Characterization of rabbit anti-PCTAIRE1 antibody and correlation of PCTAIRE1 and p27 expression. Supplementary Fig. S8. PCTAIRE1 expression is upregulated in cancers, and high PCTAIRE1 levels correlate with poor patient prognosis. Supplementary Table S1. Specific interaction of PCTAIRE1 with p27.
Supplemental Table S2 from H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis
Authors: Wu Pei-Chun , Lu Jeng-Wei , Yang Jer-Yen , Lin I-Hsuan , Ou Da-Liang , Lin Yu-Hsiang , Chou Kuan-Hsien , Huang Wen-Feng , Wang Wan-Ping , Huang Yih-Leh , Hsu Chiun , Lin Liang-In , Lin Yueh-Min , Shen C.-K. James , Tzeng Tsai-Yu
Published: April 2023

Clinicopathological characteristics of patients with lung cancer.
Supplemental Figure S8 from H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis
Authors: Wu Pei-Chun , Lu Jeng-Wei , Yang Jer-Yen , Lin I-Hsuan , Ou Da-Liang , Lin Yu-Hsiang , Chou Kuan-Hsien , Huang Wen-Feng , Wang Wan-Ping , Huang Yih-Leh , Hsu Chiun , Lin Liang-In , Lin Yueh-Min , Shen C.-K. James , Tzeng Tsai-Yu
Published: April 2023

ANXA2 is highly expressed in metastatic cancer cells.
Supplemental Figure S6 from H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis
Authors: Wu Pei-Chun , Lu Jeng-Wei , Yang Jer-Yen , Lin I-Hsuan , Ou Da-Liang , Lin Yu-Hsiang , Chou Kuan-Hsien , Huang Wen-Feng , Wang Wan-Ping , Huang Yih-Leh , Hsu Chiun , Lin Liang-In , Lin Yueh-Min , Shen C.-K. James , Tzeng Tsai-Yu
Published: April 2023

The KMT1E mutation (H1224A) does not suppress ANXA2 promoter activity in cancer cells.
Supplentary Figures 1-6 from DUSP1 Phosphatase Regulates the Proinflammatory Milieu in Head and Neck Squamous Cell Carcinoma
Authors: Zhang Xiaoyi , Hyer J. Madison , Yu Hong , D'Silva Nisha J. , Kirkwood Keith L.
Published: April 2023

Supplementary Figures 1-6 Supplemental Figure 1. Animals underwent weekly oral examinations after carcinogen withdrawal for the development of oral lesions. Supplemental Figure 2. Animals were monitored weekly for weight change as a surrogate measure for tumor burden Supplemental Figure 3. Macrophage polarization gene expression in tumor tissues by Nanostring Analysis. Supplemental Figure 4. Effect of DUSP1 expression on progression-free survival in breast Cancer. Supplemental Figure 5. Immunohistochemistry for phosphorylated forms of the MAPKs Supplemental Figure 6. Whole tumor lysates were assessed for phosphorylated and total forms of MAPKs
Supplementary Table S1 from Harnessing the Fcμ Receptor for Potent and Selective Cytotoxic Therapy of Chronic Lymphocytic Leukemia
Authors: Vire Bérengère , Skarzynski Martin , Thomas Joshua D. , Nelson Christopher G. , David Alexandre , Aue Georg , Burke Terrence R. , Rader Christoph , Wiestner Adrian
Published: April 2023

This table describes treatment naive patients characteristics.
Supplementary Materials and Methods from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche
Authors: Vadrevu Surya Kumari , Chintala Navin K. , Sharma Sharad K. , Sharma Priya , Cleveland Clayton , Riediger Linley , Manne Sasikanth , Fairlie David P. , Gorczyca Wojciech , Almanza Othon , Karbowniczek Magdalena , Markiewski Maciej M.
Published: April 2023

PDF file - 209KB
Supplementary Figures 1 - 5 from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche
Authors: Vadrevu Surya Kumari , Chintala Navin K. , Sharma Sharad K. , Sharma Priya , Cleveland Clayton , Riediger Linley , Manne Sasikanth , Fairlie David P. , Gorczyca Wojciech , Almanza Othon , Karbowniczek Magdalena , Markiewski Maciej M.
Published: April 2023

PDF file - 981KB, Liver metastasis, C5aR expression on myeloid, 4T1 and T cells, infiltration of CD8+ T cells and MDSCs in livers of breast tumor-bearing mice (S1). MDSCs infiltrate lungs of breast tumor bearing mice prior to metastases (S2). Complement production and activation in tumor bearing mice and C5aR expression in lymph nodes of breast cancer patients (S3). Gating for regulatory T (Treg) cells (S4). Gating for cytokine producing myeloid cells (S5).
Supplementary Methods, Figures 1 - 8 from Selenium Suppresses Leukemia through the Action of Endogenous Eicosanoids
Authors: Gandhi Ujjawal H. , Kaushal Naveen , Hegde Shailaja , Finch Emily R. , Kudva Avinash K. , Kennett Mary J. , Jordan Craig T. , Paulson Robert F. , Prabhu K. Sandeep
Published: April 2023

PDF file - 772KB, Supplementary Figure 1. Selenium supplementation abrogates leukemia in a Friend leukemia (FVP) model. Supplementary Figure 2. Effect of selenium supplementation on the splenic histopathology in FVP-infected mice. Supplementary Figure 3. Selenium supplementation increases apoptosis in the spleen of FVP infected mice.Supplementary Figure 4. Essential role of the COX/eicosanoid pathway in the ablation of LSCs in FVP-infected Se-S mice. Supplementary Figure 5. Modulation of expression of NADPH oxidases (A) and Gpx4 (B) by selenium-treatment of BCR-ABL+LSCs. Supplementary Figure 6. Expression of Tp53, Cat and Sod2 in the spleen of FVP-infected mice. Supplementary Figure 7. Activation of p53 in FVP-infected Se-S and MSA mice. Supplementary Figure 8. Selenium-dependent expression of selenoproteins and CyPG synthesis machinery and endogenous production of 12-PGJ2 by LC-MS/MS in BCRABL+ LSCs.
Supplemental Figure 4 from HTLV-1 bZIP Factor HBZ Promotes Cell Proliferation and Genetic Instability by Activating OncomiRs
Authors: Vernin Céline , Thenoz Morgan , Pinatel Christiane , Gessain Antoine , Gout Olivier , Delfau-Larue Marie-Hélène , Nazaret Nicolas , Legras-Lachuer Catherine , Wattel Eric , Mortreux Franck
Published: April 2023

Supplemental Figure 4. Gene ontology analysis of miRNA regulatory pathways in infected CD4+ T-cells.
Supplementary Figure Legend from Translesion Polymerase η Is Upregulated by Cancer Therapeutics and Confers Anticancer Drug Resistance
Authors: Tomicic Maja T. , Aasland Dorthe , Naumann Steffen C. , Meise Ruth , Barckhausen Christina , Kaina Bernd , Christmann Markus
Published: April 2023

Supplementary Figure Legend
Supplementary Figure 3 from Development of Novel ADCs: Conjugation of Tubulysin Analogues to Trastuzumab Monitored by Dual Radiolabeling
Authors: Cohen Ruth , Vugts Danielle J. , Visser Gerard W.M. , Stigter-van Walsum Marijke , Bolijn Marije , Spiga Marco , Lazzari Paolo , Shankar Sreejith , Sani Monica , Zanda Matteo , van Dongen Guus A.M.S.
Published: April 2023

In vivo biodistribution. The complete biodistribution in JIMT-tumor bearing mice of A 131-I-TUB-OMOM-trastuzumab (2 eq) at 3, 24, 48 and 72 h after injection and B 131-I-TUB-OMOM-trastuzumab (4 eq) at 3, 24, 48 and 72 h after injection. The black bars show the 131-I data, the grey bars show the 89-Zr data; data are presented as %ID/g {plus minus} SD.
Supplementary Figure 2 from Development of Novel ADCs: Conjugation of Tubulysin Analogues to Trastuzumab Monitored by Dual Radiolabeling
Authors: Cohen Ruth , Vugts Danielle J. , Visser Gerard W.M. , Stigter-van Walsum Marijke , Bolijn Marije , Spiga Marco , Lazzari Paolo , Shankar Sreejith , Sani Monica , Zanda Matteo , van Dongen Guus A.M.S.
Published: April 2023

Blood kinetics of 131-I-TUB-OH-trastuzumab (2 eq; dashed line) and 124-I-trastuzumab in non-tumor bearing mice. Data are presented as %ID/g {plus minus} SD.
Supplementary Figure S6 from Stress Response Protein Cirp Links Inflammation and Tumorigenesis in Colitis-Associated Cancer
Authors: Sakurai Toshiharu , Kashida Hiroshi , Watanabe Tomohiro , Hagiwara Satoru , Mizushima Tsunekazu , Iijima Hideki , Nishida Naoshi , Higashitsuji Hiroaki , Fujita Jun , Kudo Masatoshi
Published: April 2023

Figure S6. (A) Representative images of immunohistochemical detection of E-cadherin, a marker for epithelial cells, and TUNEL staining of tumors from AOM + DSS-treated mice. (B) Representative immunostaining images of colonic mucosa of non-treated (DSS -), DSS-treated (DSS) and AOM + DSS-treated mice (AOM + DSS) using anti-PCNA antibody. Scale bar, 100 microm.
Supplementary Figure S4 from Stress Response Protein Cirp Links Inflammation and Tumorigenesis in Colitis-Associated Cancer
Authors: Sakurai Toshiharu , Kashida Hiroshi , Watanabe Tomohiro , Hagiwara Satoru , Mizushima Tsunekazu , Iijima Hideki , Nishida Naoshi , Higashitsuji Hiroaki , Fujita Jun , Kudo Masatoshi
Published: April 2023

Figure S4. (A) Colonic lysates from DSS-treated WT and Cirp-/- mice were immunoblotted with antibodies against the indicated proteins. (B) Relative mRNA levels in colonic tissues from mice treated with DSS, as determined by real-time qPCR (n = 4 per group). Expression level in colonic tissues from non-treated WT mice was set as 1. Results are expressed as means + SEM. *P < 0.05 compared with WT mice. (C) TNF-B mRNA level extracted from BM-derived macrophages was analyzed by real-time qPCR. (D) BM-derived macrophages were isolated from WT and Cirp-/- mice and cell lysates were immunoblotted with antibodies against the indicated proteins.
Supplementary Figure S6 from IGF2 Preserves Osteosarcoma Cell Survival by Creating an Autophagic State of Dormancy That Protects Cells against Chemotherapeutic Stress
Authors: Shimizu Takatsune , Sugihara Eiji , Yamaguchi-Iwai Sayaka , Tamaki Sakura , Koyama Yuko , Kamel Walied , Ueki Arisa , Ishikawa Tomoki , Chiyoda Tatsuyuki , Osuka Satoru , Onishi Nobuyuki , Ikeda Hiroko , Kamei Junzo , Matsuo Koichi , Fukuchi Yumi , Nagai Toshihiro , Toguchida Junya , Toyama Yoshiaki , Muto Akihiro , Saya Hideyuki
Published: April 2023

Supplementary Figure S6: (A) Serum concentrations of Asp, Gln, and Glu in mice. (B) H&E staining of representative AXT cell-derived tumors from mice treated with chemotherapy plus L-asparaginase or bafilomycin A as in Figure 6A. (C) Proposed model for the role of IGF- or insulin-mediated dormancy in osteosarcoma cells.
Supplementary Figure Legends from Immunosuppressive Myeloid Cells Induced by Chemotherapy Attenuate Antitumor CD4+ T-Cell Responses through the PD-1–PD-L1 Axis
Authors: Ding Zhi-Chun , Lu Xiaoyun , Yu Miao , Lemos Henrique , Huang Lei , Chandler Phillip , Liu Kebin , Walters Matthew , Krasinski Antoni , Mack Matthias , Blazar Bruce R. , Mellor Andrew L. , Munn David H. , Zhou Gang
Published: April 2023

PDF file - 30KB
Supplementary Figure S2 from IGF2 Preserves Osteosarcoma Cell Survival by Creating an Autophagic State of Dormancy That Protects Cells against Chemotherapeutic Stress
Authors: Shimizu Takatsune , Sugihara Eiji , Yamaguchi-Iwai Sayaka , Tamaki Sakura , Koyama Yuko , Kamel Walied , Ueki Arisa , Ishikawa Tomoki , Chiyoda Tatsuyuki , Osuka Satoru , Onishi Nobuyuki , Ikeda Hiroko , Kamei Junzo , Matsuo Koichi , Fukuchi Yumi , Nagai Toshihiro , Toguchida Junya , Toyama Yoshiaki , Muto Akihiro , Saya Hideyuki
Published: April 2023

Supplementary Figure S2: (A) Representative flow cytometric analysis of DNA content in AXT cells. (B) Cell cycle distribution for cells treated as in (A). (C) Immunofluorescence analysis of Ki67 expression in AXT cells. (D) Representative flow cytometric analysis of Ki67 expression in AXT cells cultured in the presence of insulin. (E) Representative flow cytometric analysis of DNA content in SAOS2 cells. (F) Cell cycle distribution for cells treated as in (E). (G) Immunoblot analysis of cyclin expression in AXT cells.
Supplementary Figure S6 from Oncoprotein HBXIP Modulates Abnormal Lipid Metabolism and Growth of Breast Cancer Cells by Activating the LXRs/SREBP-1c/FAS Signaling Cascade
Authors: Zhao Yu , Li Hang , Zhang Yingyi , Li Leilei , Fang Runping , Li Yinghui , Liu Qian , Zhang Weiying , Qiu Liyan , Liu Fabao , Zhang Xiaodong , Ye Lihong
Published: April 2023

HBXIP modulates abnormal lipid metabolism of breast cancer cells through a HBXIP/LXRs/SREBP-1c/FAS signaling.
Supplementary Figure S2 from Oncoprotein HBXIP Modulates Abnormal Lipid Metabolism and Growth of Breast Cancer Cells by Activating the LXRs/SREBP-1c/FAS Signaling Cascade
Authors: Zhao Yu , Li Hang , Zhang Yingyi , Li Leilei , Fang Runping , Li Yinghui , Liu Qian , Zhang Weiying , Qiu Liyan , Liu Fabao , Zhang Xiaodong , Ye Lihong
Published: April 2023

HBXIP activates FAS through up-regulation of SREBP-1c transcription factor.
Supplemental Materials and Methods from Vaccine-Elicited CD8+ T Cells Cure Mesothelioma by Overcoming Tumor-Induced Immunosuppressive Environment
Authors: Tan Zhiwu , Zhou Jingying , Cheung Allen K.L. , Yu Zhe , Cheung Ka-Wai , Liang Jianguo , Wang Haibo , Lee Boon Kiat , Man Kwan , Liu Li , Yuen Kwok-Yung , Chen Zhiwei
Published: April 2023

More detailed description of materials and methods.
Supplementary Material and Methods from Promoting Thiol Expression Increases the Durability of Antitumor T-cell Functions
Authors: Kesarwani Pravin , Al-Khami Amir A. , Scurti Gina , Thyagarajan Krishnamurthy , Kaur Navtej , Husain Shahid , Fang Quan , Naga Osama S. , Simms Patricia , Beeson Gyda , Voelkel-Johnson Christina , Garrett-Mayer Elizabeth , Beeson Craig C. , Nishimura Michael I. , Mehrotra Shikhar
Published: April 2023

Supplementary Material and Methods. The file includes descriptive methodology and contains supplementary table 1 with primer sequences used throughout the paper.
Supplementary Table S5 from Long Noncoding RNA GAPLINC Regulates CD44-Dependent Cell Invasiveness and Associates with Poor Prognosis of Gastric Cancer
Authors: Hu Ye , Wang Jilin , Qian Jin , Kong Xuan , Tang Jieting , Wang Yingchao , Chen Haoyan , Hong Jie , Zou Weiping , Chen Yingxuan , Xu Jie , Fang Jing-Yuan
Published: April 2023

Supplementary Table S5. Growth of human gastric cancer xenograft in nude mice injected by GAPLINC stable knockdown clone and control clone.
Supplementary Table S2 from Long Noncoding RNA GAPLINC Regulates CD44-Dependent Cell Invasiveness and Associates with Poor Prognosis of Gastric Cancer
Authors: Hu Ye , Wang Jilin , Qian Jin , Kong Xuan , Tang Jieting , Wang Yingchao , Chen Haoyan , Hong Jie , Zou Weiping , Chen Yingxuan , Xu Jie , Fang Jing-Yuan
Published: April 2023

Supplementary Table S2. LncRNAs associated with CNVs.
Supplementary Table S1 from Long Noncoding RNA GAPLINC Regulates CD44-Dependent Cell Invasiveness and Associates with Poor Prognosis of Gastric Cancer
Authors: Hu Ye , Wang Jilin , Qian Jin , Kong Xuan , Tang Jieting , Wang Yingchao , Chen Haoyan , Hong Jie , Zou Weiping , Chen Yingxuan , Xu Jie , Fang Jing-Yuan
Published: April 2023

Supplementary Table S1. Deregulated lncRNAs in gastric cancer.
Supplementary Figures S1-S4 from Long Noncoding RNA GAPLINC Regulates CD44-Dependent Cell Invasiveness and Associates with Poor Prognosis of Gastric Cancer
Authors: Hu Ye , Wang Jilin , Qian Jin , Kong Xuan , Tang Jieting , Wang Yingchao , Chen Haoyan , Hong Jie , Zou Weiping , Chen Yingxuan , Xu Jie , Fang Jing-Yuan
Published: April 2023

Supplementary Figures S1-S4. Binding of transcription factors to upregulated lncRNAs (S1); P53 mutant R248W transactivated GAPLINC through specifically binding to its promoter (S2); Knockdown of GAPLINC by two different siRNAs respectively inhibited gastric cancer cell proliferation (S3); CD44 could rescue the invasion inhibition effect of GAPLINC knockdown (S4).
Supplemental Figure S4 from Zfx Facilitates Tumorigenesis Caused by Activation of the Hedgehog Pathway
Authors: Palmer Colin J. , Galan-Caridad Jose M. , Weisberg Stuart P. , Lei Liang , Esquilin Jose M. , Croft Gist F. , Wainwright Brandon , Canoll Peter , Owens David M. , Reizis Boris
Published: April 2023

The expression of Zfx in different molecular subtypes of MB.
Supplemental Figure S2 from Zfx Facilitates Tumorigenesis Caused by Activation of the Hedgehog Pathway
Authors: Palmer Colin J. , Galan-Caridad Jose M. , Weisberg Stuart P. , Lei Liang , Esquilin Jose M. , Croft Gist F. , Wainwright Brandon , Canoll Peter , Owens David M. , Reizis Boris
Published: April 2023

Zfx co-deletion impairs BCC progression after Hh pathway activation by expression of a constitutively active Smo allele.
Supplementary Figure 9 from Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFNγ
Authors: Ho Ping-Chih , Meeth Katrina M. , Tsui Yao-Chen , Srivastava Bhaskar , Bosenberg Marcus W. , Kaech Susan M.
Published: April 2023

PDF file - 260KB, Supplementary Figure 9. BrafV600E/Pten melanoma cells do not express CD40.
Supplementary Figure 7 from Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFNγ
Authors: Ho Ping-Chih , Meeth Katrina M. , Tsui Yao-Chen , Srivastava Bhaskar , Bosenberg Marcus W. , Kaech Susan M.
Published: April 2023

PDF file - 71KB, Supplementary Figure 7. IFNg blockade did not affect TAMs and TIDCs frequencies in BrafV600E/Pten melanomas.
Data Supplement from TALEN-Mediated Somatic Mutagenesis in Murine Models of Cancer
Authors: Zhang Shuyuan , Li Lin , Kendrick Sara L. , Gerard Robert D. , Zhu Hao
Published: April 2023

Supplementary Figure 3. liver picture, genotyping and sequencing data for β-catenin TALENs plus DEN induced liver tumor in C3H mice
Data Supplement from TALEN-Mediated Somatic Mutagenesis in Murine Models of Cancer
Authors: Zhang Shuyuan , Li Lin , Kendrick Sara L. , Gerard Robert D. , Zhu Hao
Published: April 2023

Supplementary Figure 4. liver picture, genotyping and sequencing data for β-catenin TALENs alone induced liver tumors in C3H mice
Data Supplement from TALEN-Mediated Somatic Mutagenesis in Murine Models of Cancer
Authors: Zhang Shuyuan , Li Lin , Kendrick Sara L. , Gerard Robert D. , Zhu Hao
Published: April 2023

Supplementary Table 1. Characteristics of β-catenin and Apc TALENs
Supplementary Figure 6 from Engineered Fusokine GIFT4 Licenses the Ability of B Cells to Trigger a Tumoricidal T-cell Response
Authors: Deng Jiusheng , Yuan Shala , Pennati Andrea , Murphy Jordan , Wu Jian Hui , Lawson David , Galipeau Jacques
Published: April 2023

PDF file - 161K, human GIFT4 induces B-cell mediated anti-melanoma T cell response.
Supplementary Figure 5 from Engineered Fusokine GIFT4 Licenses the Ability of B Cells to Trigger a Tumoricidal T-cell Response
Authors: Deng Jiusheng , Yuan Shala , Pennati Andrea , Murphy Jordan , Wu Jian Hui , Lawson David , Galipeau Jacques
Published: April 2023

PDF file - 98K, B6 mice treated with GIFT4 protein or implanted with B16-GIFT4 cells do not produce anti-GIFT4 antibodies.
Supplementary Figure 1 from Engineered Fusokine GIFT4 Licenses the Ability of B Cells to Trigger a Tumoricidal T-cell Response
Authors: Deng Jiusheng , Yuan Shala , Pennati Andrea , Murphy Jordan , Wu Jian Hui , Lawson David , Galipeau Jacques
Published: April 2023

PDF file - 134K, GIFT4 induces the proliferation of murine splenocytes.
Supplementary Figure S2 from Myostatin Gene Inactivation Prevents Skeletal Muscle Wasting in Cancer
Authors: Gallot Yann S. , Durieux Anne-Cécile , Castells Josiane , Desgeorges Marine M. , Vernus Barbara , Plantureux Léa , Rémond Didier , Jahnke Vanessa E. , Lefai Etienne , Dardevet Dominique , Nemoz Georges , Schaeffer Laurent , Bonnieu Anne , Freyssenet Damien G.
Published: April 2023

Mstn gene inactivation prevents loss of skeletal muscle in tumor-bearing mice.
Supplementary Figure S1 from Myostatin Gene Inactivation Prevents Skeletal Muscle Wasting in Cancer
Authors: Gallot Yann S. , Durieux Anne-Cécile , Castells Josiane , Desgeorges Marine M. , Vernus Barbara , Plantureux Léa , Rémond Didier , Jahnke Vanessa E. , Lefai Etienne , Dardevet Dominique , Nemoz Georges , Schaeffer Laurent , Bonnieu Anne , Freyssenet Damien G.
Published: April 2023

Plasma concentration of amino acids.
Supplementary Figure S2 from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary Figure S2. Exogenous overexpression of RIP140 does not affect RIP140 chromatin interactions.
Supplementary Materials and Methods, Figures S1-S7, Table S1 from Bioengineered Implantable Scaffolds as a Tool to Study Stromal-Derived Factors in Metastatic Cancer Models
Authors: Bersani Francesca , Lee Jungwoo , Yu Min , Morris Robert , Desai Rushil , Ramaswamy Sridhar , Toner Mehmet , Haber Daniel A. , Parekkadan Biju
Published: April 2023

Supplementary Materials and Methods, Figures S1-S7, Table S1. Supplementary Materials and Methods. Porous hydrogel scaffold fabrication; 3D culture of primary human bone marrow stromal cells; In vitro invasion assay; In vitro proliferation assay. Supplementary Figure S1. In vitro PC-3 cell invasion and proliferation assays. Supplementary Figure S2. Human BMSC survival in vivo and marrow-like microenvironment formation in scaffolds 4 weeks after subdermal implantation in NSG mice. Supplementary Figure S3. Longitudinal bioluminescence monitoring of human tumor xenografts. Supplementary Figure S4. Histological analysis of PC-3 cells. Supplementary Figure S5. Ex vivo monitoring of DU-145 and MDA-231 #1833 cell engraftment in explanted scaffolds. Supplementary Figure S6. Metastasis development in DU-145 and MDA-231 #1833 xenograft models after scaffold transplantation. Supplementary Figure S7. Effect of IL-1Ra and IL-1b on PC-3 cell growth. Supplementary Table S1. Comprehensive list of genes interrogated by the Mouse Tumor Metastasis RT2 Profiler PCR Array.
Supplementary Figure Legends from Host Deficiency in Caveolin-2 Inhibits Lung Carcinoma Tumor Growth by Impairing Tumor Angiogenesis
Authors: Liu Yajun , Jang Sungchan , Xie Leike , Sowa Grzegorz
Published: April 2023

Supplementary Figure Legends
Supplemental Methods and Figure Legends from IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia
Authors: Ogawara Yoko , Katsumoto Takuo , Aikawa Yukiko , Shima Yutaka , Kagiyama Yuki , Soga Tomoyoshi , Matsunaga Hironori , Seki Takahiko , Araki Kazushi , Kitabayashi Issay
Published: April 2023

Supplemental Methods and Figure Legends
Supplemental Figure S1 from IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia
Authors: Ogawara Yoko , Katsumoto Takuo , Aikawa Yukiko , Shima Yutaka , Kagiyama Yuki , Soga Tomoyoshi , Matsunaga Hironori , Seki Takahiko , Araki Kazushi , Kitabayashi Issay
Published: April 2023

Expression analysis of four mutant genes in AML cells.
Supplemental Figure 6 from A Systematic Analysis Reveals Heterogeneous Changes in the Endocytic Activities of Cancer Cells
Authors: Elkin Sarah R. , Bendris Nawal , Reis Carlos R. , Zhou Yunyun , Xie Yang , Huffman Kenneth E. , Minna John D. , Schmid Sandra L.
Published: April 2023

Supplemental Figure 6: Relationship between endocytic activity and adhesion.