bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamic Responses of Train-Symmetry-Bridge System Considering Concrete Creep and the Creep-Induced Track Irregularity
Authors: Li Wenfeng , Ma Hongkai , Wei Minglong , Xiang Ping , Tang Fang , Gao Binwei , Zhou Qishi
Published: September 2023

This work considers the influence of concrete creep on track irregularities and establishes the dynamic motion equation of the train-track-bridge coupling system. The track irregularity is obtained by superposition of the initial geometric irregularity and additional geometric irregularity of the steel rail caused by creep. When high-speed railway trains pass through bridges; the vertical acceleration and vertical displacement of continuous beam bridges are related to the train’s operating speed, and the influence of creep camber is relatively small. At the same time, considering the randomness of track irregularities, the dynamic responses of the train track bridge coupling system under the action of random track irregularities are analyzed, and the dynamic responses of trains at different operating speeds are obtained. The deterministic and uncertain dynamic responses of the train track bridge system were compared and analyzed to verify the accuracy of the Karhunen Loéve expansion (KLE)-Point estimate method (PEM) calculation results. The results indicate that the random characteristics of track irregularities have a significant impact on train dynamic response. Based on the random system vibration analysis and considering the safety and comfort indicators of high-speed railway trains, the creep deformation limit of a continuous beam bridge with a length of 48 m + 80 m + 48 m is obtained to be 19 mm. This is the first time that the dynamic responses of train-symmetry-bridge system are calculated by considering concrete creep and the creep-induced track irregularity, which has certain significance for understanding the dynamics of train -bridge system. In addition, the proposed creep threshold is also of great significance to ensure the safety of traveling.
The Novel Yersinia enterocolitica Telomere Phage vB_YenS_P840 Is Closely Related to PY54, but Reveals Some Striking Differences
Authors: Bräuer Julia Anabell , Hammerl Jens Andre , El-Mustapha Sabrin , Fuhrmann Julius , Barac Andrea , Hertwig Stefan
Published: September 2023

Telomere phages are a small group of temperate phages, whose prophages replicate as a linear plasmid with covalently closed ends. They have been isolated from some Enterobacteriaceae and from bacterial species living in aquatic environments. Phage PY54 was the first Yersinia (Y.) enterocolitica telomere phage isolated from a nonpathogenic O:5 strain, but recently a second telomeric Yersinia phage (vB_YenS_P840) was isolated from a tonsil of a wild boar in Germany. Both PY54 and vB_YenS_P840 (P840) have a siphoviridal morphology and a similar genome organization including the primary immunity region immB and telomere resolution site telRL. However, whereas PY54 only possesses one prophage repressor for the lysogenic cycle, vB_YenS_P840 encodes two. The telRL region of this phage was shown to be processed by the PY54 protelomerase under in vivo conditions, but unlike with PY54, a flanking inverted repeat was not required for processing. A further substantial difference between the phages is their host specificity. While PY54 infects Y. enterocolitica strains belonging to the serotypes O:5 and O:5,27, vB_YenS_P840 exclusively lyses O:3 strains. As the tail fiber and tail fiber assembly proteins of the phages differ significantly, we introduced the corresponding genes of vB_YenS_P840 by transposon mutagenesis into the PY54 genome and isolated several mutants that were able to infect both serotypes, O:5,27 and O:3.
Viral Entry Inhibitors Protect against SARS-CoV-2-Induced Neurite Shortening in Differentiated SH-SY5Y Cells
Authors: Mignolet Margaux , Gilloteaux Jacques , Halloin Nicolas , Gueibe Matthieu , Willemart Kévin , De Swert Kathleen , Bielarz Valéry , Suain Valérie , Pastushenko Ievgenia , Gillet Nicolas Albert , Nicaise Charles
Published: September 2023

The utility of human neuroblastoma cell lines as in vitro model to study neuro-invasiveness and neuro-virulence of SARS-CoV-2 has been demonstrated by our laboratory and others. The aim of this report is to further characterize the associated cellular responses caused by a pre-alpha SARS-CoV-2 strain on differentiated SH-SY5Y and to prevent its cytopathic effect by using a set of entry inhibitors. The susceptibility of SH-SY5Y to SARS-CoV-2 was confirmed at high multiplicity-of-infection, without viral replication or release. Infection caused a reduction in the length of neuritic processes, occurrence of plasma membrane blebs, cell clustering, and changes in lipid droplets electron density. No changes in the expression of cytoskeletal proteins, such as tubulins or tau, could explain neurite shortening. To counteract the toxic effect on neurites, entry inhibitors targeting TMPRSS2, ACE2, NRP1 receptors, and Spike RBD were co-incubated with the viral inoculum. The neurite shortening could be prevented by the highest concentration of camostat mesylate, anti-RBD antibody, and NRP1 inhibitor, but not by soluble ACE2. According to the degree of entry inhibition, the average amount of intracellular viral RNA was negatively correlated to neurite length. This study demonstrated that targeting specific SARS-CoV-2 host receptors could reverse its neurocytopathic effect on SH-SY5Y.
Severe Neurologic Disease in a Horse Caused by Tick-Borne Encephalitis Virus, Austria, 2021
Authors: de Heus Phebe , Bagó Zoltán , Weidinger Pia , Lale Dilara , Trachsel Dagmar S. , Revilla-Fernández Sandra , Matiasek Kaspar , Nowotny Norbert
Published: September 2023

As evidenced by sero-epidemiological studies, infections of horses with the tick-borne encephalitis virus (TBEV) occur frequently in TBEV-endemic areas. However, there are only very few reports of clinical cases. A possible underreporting may be due to a variety of diagnostic challenges. In this study, ELISA and neutralization tests were applied to serum samples. Brain tissue samples were investigated for the presence of nucleic acids of TBEV, Equid alphaherpesvirus 1, Borna disease virus 1, West Nile and Usutu viruses, rustrela virus, as well as Eastern, Western, and Venezuelan equine encephalitis viruses with RT-qPCR, RT-PCR, and qPCR, respectively. TBEV-specific amplification products were subjected to Sanger sequencing. In addition, a direct fluorescent antibody test for rabies was performed. Clinical and patho-histological findings are reported. Using specific RT-qPCR and RT-PCR assays, TBEV nucleic acids were demonstrated in brain tissue samples. Sequencing revealed the Western (formerly Central) European subtype of TBEV as the etiological agent. A high titer of TBEV-specific neutralizing antibodies was found in the serum. RNAscope in situ hybridization revealed TBEV RNA confined to neuronal cell bodies and processes. No other pathogens or nucleic acids thereof could be detected. Diagnostic procedures need to be carried out early after the onset of neurological signs to allow for a final etiological diagnosis of acute TBEV infections in horses.
Australasian Pigeon Circoviruses Demonstrate Natural Spillover Infection
Authors: Nath Babu Kanti , Das Tridip , Peters Andrew , Gupta Suman Das , Sarker Subir , Forwood Jade K. , Raidal Shane R. , Das Shubhagata
Published: September 2023

Pigeon circovirus (PiCV) is considered to be genetically diverse, with a relatively small circular single-stranded DNA genome of 2 kb that encodes for a capsid protein (Cap) and a replication initiator protein (Rep). Australasia is known to be the origin of diverse species of the Order Columbiformes, but limited data on the PiCV genome sequence has hindered phylogeographic studies in this species. To fill this gap, this study was conducted to investigate PiCV in 118 characteristic samples from different birds across Australia using PCR and sequencing. Eighteen partial PiCV Rep sequences and one complete PiCV genome sequence were recovered from reservoir and aberrant hosts. Phylogenetic analyses revealed that PiCV circulating in Australia was scattered across three different subclades. Importantly, one subclade dominated within the PiCV sequenced from Australia and Poland, whereas other PiCV sequenced in this study were more closely related to the PiCV sequenced from China, USA and Japan. In addition, PiCV Rep sequences obtained from clinically affected plumed whistling duck, blue billed duck and Australian magpie demonstrated natural spillover of PiCV unveiled host generalist characteristics of the pigeon circovirus. These findings indicate that PiCV genomes circulating in Australia lack host adapted population structure but demonstrate natural spillover infection.
Efficacy and Safety of Sofosbuvir/Velpatasvir Plus Ribavirin in Patients with Hepatitis C Virus-Related Decompensated Cirrhosis
Authors: Flamm Steven , Lawitz Eric , Borg Brian , Charlton Michael , Landis Charles , Reddy K. Rajender , Shiffman Mitchell , Alsina Angel , Chang Charissa , Ravendhran Natarajan , Hernandez Candido , Hézode Christophe , Scherbakovsky Stacey , Mercier Renee-Claude , Samuel Didier
Published: September 2023

A fixed-dose combination of sofosbuvir/velpatasvir (SOF/VEL) plus weight-based ribavirin (RBV) for 12 weeks is recommended for the treatment of patients with hepatitis C virus (HCV)-associated decompensated cirrhosis. However, large global studies, while confirming the effectiveness of SOF/VEL in a broad range of patients, often exclude these patients. This Phase 2, single-arm, open-label study in adult patients with HCV-associated decompensated cirrhosis in France and the USA aimed to provide further data on the safety and efficacy of SOF/VEL plus RBV for 12 weeks in this population. Patients were treated with a fixed-dose combination of SOF 400 mg/VEL 100 mg plus weight-based RBV once daily for 12 weeks. The inclusion criteria were chronic HCV infection (≥6 months), quantifiable HCV RNA at screening, Child–Turcotte–Pugh class B or C cirrhosis, and liver imaging within 6 months of Day 1 to exclude hepatocellular carcinoma. Among 32 patients who initiated treatment, 78.1% achieved sustained virologic response 12 weeks after the end of treatment (SVR12). Failure to achieve SVR12 was due to non-virologic reasons (investigator discretion, n = 1; death, n = 6). All 25 patients in the per-protocol population achieved SVR12 and all but one achieved sustained virologic response 24 weeks after the end of treatment. Adverse events (AEs) were as expected for a patient population with advanced liver disease. All Grade 3–4 and serious AEs and deaths were deemed unrelated to treatment. In patients with HCV-associated decompensated cirrhosis, SOF/VEL plus RBV achieved high SVR12 rates and was generally well tolerated.
Current Knowledge on the Interaction of Human Cytomegalovirus Infection, Encoded miRNAs, and Acute Aortic Syndrome
Authors: Nappi Francesco , Alzamil Almothana , Avtaar Singh Sanjeet Singh , Spadaccio Cristiano , Bonnet Nicolas
Published: September 2023

Aortic dissection is a clinicopathological entity caused by rupture of the intima, leading to a high mortality if not treated. Over time, diagnostic and investigative methods, antihypertensive therapy, and early referrals have resulted in improved outcomes according to registry data. Some data have also emerged from recent studies suggesting a link between Human Cytomegalovirus (HCMV) infection and aortic dissection. Furthermore, the use of microRNAs has also become increasingly widespread in the literature. These have been noted to play a role in aortic dissections with elevated levels noted in studies as early as 2017. This review aims to provide a broad and holistic overview of the role of miRNAs, while studying the role of HCMV infection in the context of aortic dissections. The roles of long non-coding RNAs, circular RNAs, and microRNAs are explored to identify changes in expression during aortic dissections. The use of such biomarkers may one day be translated into clinical practice to allow early detection and prognostication of outcomes and drive preventative and therapeutic options in the future.
Scrutinization of Waste Discharge Concentrations in Eyring-Powell Nanofluid Past a Deformable Horizontal Plane Surface
Authors: Elattar Samia , Khan Umair , Zaib Aurang , Ishak Anuar , Saleh Wafaa , Abed Ahmed
Published: September 2023

Nanomaterials have been the focus of intense study and growth in the modern era across the globe because of their outstanding qualities, which are brought about by their nanoscale size; for instance, increased adsorption and catalysis capabilities plus significant reactivity. Multiple investigations have verified the fact that nanoparticles may successfully remove a variety of pollutants from water, and, as a result, they have been utilized in the treatment of both water and wastewater. Therefore, the current research intent is to examine the nonlinear heat source/sink influence on the 3D flow of water-based silver nanoparticles incorporated in an Eyring–Powell fluid across a deformable sheet with concentration pollutants. Silver particles have been used intensively to filter water, due to their potent antibacterial properties. The leading equations involving partial differential equations are renewed into the form of ordinary ordinary differential equations through utilizing the appropriate similarity technique. Then, these converted equations are solved by utilizing an efficient solver bvp4c. Visual displays and extensive exploration of the different impacts of the non-dimensional parameters on the concentration, temperature, and velocity profiles are provided. Also, the important engineering variables including skin friction, the rate of heat, and mass transfer are examined. The findings suggest that the mass transfer rate declines due to pollutant parameters. Also, the results suggest that the friction factor is uplifted by about 15% and that the heat transfer rate, as well as the mass transfer rate, declines by about 21%, due to the presence of the nanoparticle volume fraction. We believe that these results may improve the flow rate of nanofluid systems, improve heat transfer, and reduce pollutant dispersal.
Estimation of the Actual Specific Consumption in Drinking Water Supply Systems in Burkina Faso (West Africa): Potential Implications for Infrastructure Sizing
Authors: Mounirou Lawani Adjadi , Sawadogo Boukary , Yanogo Hélène , Yonaba Roland , Zorom Malicki , Faye Moussa Diagne , Kafando Moussa Bruno , Biaou Angelbert Chabi , Koïta Mahamadou , Karambiri Harouna
Published: September 2023

Specific consumption is a key parameter in estimating the water demand and further optimising the sizing of Drinking Water Supply Systems (DWSS) infrastructure. DWSS are globally used to provide safe drinking water in urban and rural settings, and their design cost is critical for water authorities, especially in low-income countries. In this study, the optimal of the specific consumption value is carried out in Burkina Faso (West Africa). The methodology adopted a statistical analysis of operational data collected on 40 DWSS systems in Burkina Faso, further completed by a multiple correspondence analysis (MCA) of determinants of the water demand and cluster identification and analysis through Agglomerative Hierarchical Clustering (AHC). The results show that the actual consumption is lower than the common estimate used in sizing. Statistical analysis revealed that actual specific consumption is affected by various parameters, the most relevant of which are the reliance on alternative resources, the presence of waterways and the local climate seasonality. The average actual specific consumption is estimated at 3.83 ± 3.43 L/people/day. Finally, a decision tree for the choice of suitable specific consumption value as a function of the physical settings of a given area is proposed for optimal sizing of DDWS systems in Burkina Faso.
Intrinsic Vulnerability Assessment of the Qingduo Karst System, Henan Province
Authors: Yin Leihao , Xu Beiyi , Cai Wutian , Zhou Pengpeng , Yang Li
Published: September 2023

Groundwater vulnerability assessments are vital for protecting valuable resources by revealing susceptibility to contamination. This study developed an enhanced index model to assess the intrinsic vulnerability of a supplied karst aquifer in Qingduo, Henan Province. The model considered the 3-D geological structure and modified indices to account for Northern China’s mild karstification. Emphasizing the absolute infiltration capacity of surface contaminants, the model also integrated the groundwater sources and sinks (SS) index. The vulnerability map revealed that over 60% of the aquifers, including the Qingduo wellfield, exhibited very low to low vulnerability. Conversely, only small areas (<5%) along the Kejing (KJ) fault’s southern wall were classified as highly vulnerable. These findings highlighted the significant role of groundwater flow alongside aquifer conditions. The upward groundwater flow through the Fengmenkou (FMK) faults slowed the downward infiltration of surface contaminants into the lower karst aquifer, effectively reducing vulnerabilities. Lower levels of dissolved lead (Pb) and nitrate (NO3−) in Qingduo groundwater aligned with PISSR vulnerability mapping. Sensitivity analysis assessed the results’ sensitivity to index weight assignment. The inclusion of the sources and sinks (SS) index holds implications for semi-quantitatively assessing dynamic groundwater vulnerability by delineating flow patterns.
Lag Time and Cumulative Effects of Climate Factors on Drought in North China Plain
Authors: Zhang Zezhong , Wang Zipeng , Lai Hexin , Wang Fei , Li Yanbin , Feng Kai , Qi Qingqing , Di Danyang
Published: September 2023

The growing concern surrounding climate change has gradually drawn attention to the influence of climate factors on drought occurrence. In order to effectively prevent the occurrence of drought and reasonably utilize water resources, the vegetation health index (VHI) was used to characterize drought in North China Plain (NCP) in this study. Furthermore, six climate factors: air temperature (AT), precipitation (P), evapotranspiration (ET), specific humidity (SH), soil moisture (SM), and soil temperature (ST) were selected. The pole symmetric mode decomposition (PSMD) and improved gridded trend test (IGT) were used to analyze the spatial–temporal characteristics of drought and climate factors in NCP from 1982 to 2020. By calculating the cumulative climatic factors of 0 months, 1 month, 2 months, and 3 months, the correlation between drought and the climatic factors with different cumulative scales was analyzed. The results showed that: (1) from 1982 to 2020, the drought in NCP showed a downward trend and the climate factors showed an upward trend; (2) with the increase in AT, P, ET, SH, SM, and ST, VHI showed an upward trend, and SM showed the strongest correlation with VHI; (3) the optimal cumulative lag time (CLT) for AT, P, ET, SH, SM, and ST were 1.67 months, 1.48 months, 1.95 months, 1.69 months, 0.89 months, and 1.81 months, respectively; and (4) AT was the main driving factor of drought in NCP. This study contributes to the early warning and prediction of drought events, providing a scientific basis for water management authorities in drought management and decision making, and mitigating the negative impacts of drought on socio-economic aspects.
Study on Excavation Response of Deep Foundation Pit Supported by SMW Piles Combined with Internal Support in Soft Soil Area
Authors: Tu Bingxiong , Zheng Jinhuo , Ye Shuaihua , Shen Minglong
Published: September 2023

Based on a foundation pit project in Fuzhou, China, the influence of foundation pit excavation on the supporting structure and surrounding environment in a soft-soil area is studied. This study was based on actual monitoring data and investigated the variations in the supporting structure, surrounding constructions, and groundwater levels during excavation. The analysis of the monitoring data demonstrates the presence of pronounced ‘spatial effects’ and ‘temporal effects’ on the deformation of the support structure and surrounding structures. The deformation of the support structure and surrounding structures exhibits distinct spatial distribution characteristics at different locations along the excavation pit wall. Typically, more significant deformations are observed in the middle section of the pit wall, while deformations decrease as the distance from the pit corner decreases. The support structure’s and surrounding structures’ deformation characteristics vary during different construction stages. During the excavation phase, the rate of deformation increase in the support structure and surrounding structures is notably higher. In contrast, during the construction of the underground basement floor and the backfilling phase of the excavation pit, the rate of deformation increase in the support structure and surrounding structures is relatively lower. Throughout the entire construction period of the excavation pit, the groundwater level in the vicinity of the pit exhibits a fluctuating trend. Apart from the influence of rainfall, the overall variation in groundwater level is minimal, indicating the effective water-sealing performance of the combined Soil-Mixing Wall (SMW) support structure within the circular enclosure.
MOŻLIWOŚCI WYKORZYSTANIA SZTUCZNEJ INTELIGENCJI DO WSPIERANIA EDUKACJI INKLUZYJNEJ
Authors: Koziej Sławomir
Published: September 2023

Sztuczna inteligencja to dziedzina informatyki, skupiająca się na tworzeniu pro-gramów i systemów komputerowych zdolnych do wykonywania zadań wymagających inteligencji ludzkiej. Jest to badanie i określanie reguł rządzących inteligentnymi zachowaniami człowieka, które wykorzystuje się w algorytmach i programach. Sztuczna inteligencja ma za zadanie rozwiązywanie problemów, podejmowanie decyzji, uczenie się na podstawie danych, rozumienie języka naturalnego, przetwarzanie obrazów i dźwięków oraz wiele innych. Dzielona jest na różne kategorie, takie jak sztuczna inteligencja słaba, silna, uczenie maszynowe, sieci neuronowe i sztuczna inteligencja ogólna. Ma ogromny wpływ na różne aspekty ludzkiego życia, w tym na przemysł, transport, medycynę, handel, rolnictwo. W edukacji może wspierać uczniów poprzez personalizację nauczania, uczenie się adaptacyjne, rozpoznawanie mowy i tekstu, technologie asystujące, wykrywanie słabych stron ucznia oraz rozwijanie współpracy i komunikacji. Wykorzystanie sztucznej inteligencji w edukacji inkluzyjnej może zapewnić skuteczniejsze nauczanie, dostosowanie procesu kształcenia do indywidualnych potrzeb uczniów i wspieranie uczniów z różnymi trudnościami w pełnym uczestnictwie w procesie edukacyjnym. Jednakże istnieją także zagrożenia, takie jak brak krytycznego myślenia i empatii u uczniów oraz uzależnienie od technologii, które wymagają uwagi i odpowiednich działań zaradczych.
THE SIGNIFICANCE OF DEMOCRATIC AND CIVIL CONTROL OF SECURITY SERVICES FOR THE AIM OF PREVENTING POLITICAL VIOLENCE - CASE STUDY OF THE REPUBLIC OF SERBIA AFTER 2000
Authors:   School for Engineering Management FIM, Serbia, Životić Ilija , Obradović Darko ,   Center for Strategic Analysis, Serbia
Published: September 2023

Democratic and civilian control of the security services is the foundation of a society’s democracy. The standard of living measured through the prism of GDP, the level of the unemployment rate, social and health care, and free education are mostly only apparent factors that mask some much more complex phenomena such as the entrapment of democracy if there is no civil and democratic control of the security services, which as will be shown in their work, they very often directly decide on life and death. This especially applies to countries with totalitarian regimes in which any oppositional opinion is sanctioned or, as in the case of Serbia after 2000, in countries where democracy is still young. National security and the security of every individual citizen can be seriously threatened in cases where there is no civilian and democratic control of the security services. The absence of this type of control results in uncontrolled, unconstitutional, and illegal behavior of members of the security services, which is often characterized by the belief that its members, while committing the most serious crimes, are actually protecting their country and order from destruction. This work aims to prove the hypothesis of the need for democratic and civilian control of the security services as the basis of government through a case study of the rebellion of the Special Operations Unit of the State Security Department of the Ministry of Internal Affairs of Serbia, as well as through the case of the murder of Prime Minister Zoran Đinđić, for which members of the former security service were also legally convicted. rights in modern democratic societies.
Effect of Yeast Cell Wall on Gut Health, Immunity and Milk Production of Dairy Cattle in Normal and Heat Stress Conditions. Review
Authors: Mahasneh Ola K. , Abdelqader Anas , Al-Fataftah Abdur-Rahman A.
Published: September 2023

This review focuses on the most recent literature to bring to light the major beneficial effects of the yeast cell wall (YCW) and its products on dairy cattle. These products include viable yeast, yeast culture, nutritional yeast, and fractionated yeast products. The yeast cell wall is one of these products and belongs to the fractionated yeast products used to promote production performance and health in dairy cows.  The yeast and YCW were proven to have positive impacts on dairy cattle performance in terms of milk yield, milk components, and overall quality. As well, these products showed beneficial effects under heat stress conditions.  The YCW is a natural fermentation derivative of yeast cells such as Saccharomyces cerevisiae species consists mainly of β-glucan (29% to 64%), mannan (31%), and some other compounds like protein (13%), lipids (9%), chitin (1–2%) with β-glucan and mannan being the main bioactive molecules. The mode of action through which YCW elicit their beneficial functions in dairy cow explain their effect on cows' metabolism and digestion, immunity, rumen and intestine health, and subsequent performance and well-being. These modes of action include improving gastrointestinal (GI) tract health, stimulating immune system components as it is considered an immunomodulator additive, mycotoxin binding ability, and improving antioxidant capacity. Therefore, yeast and YCW products are one of the promising areas of ruminant nutrition in dairy cows, not only because of their nutritional and health benefits to dairy cows but also due to their negligible residual effects on dairy cows’ bodies and products.
Assessing Transfer Learning Models for Medical Image Classification: A Comparative Study on Alzheimer’s MRI, Chest CT-Scan, and Chest X-ray Images
Authors:   Department of Mathematics, Pamantasan ng Lungsod ng Maynila (University of the City of Manila), Manila, Philippines., M. Lupague Ryan Marcus Jeremy , Mabborang Romie C. ,   Department of Mathematics, Pamantasan ng Lungsod ngMaynila (University of the City ofManila),Manila, Philippines., Bansil Prof. Alvin G. ,   Department of Mathematics, Pamantasan ng Lungsod ngMaynila (University of the City ofManila),Manila, Philippines., Lupague Melinda M. ,   Department of Mathematics, Pamantasan ng Lungsod ngMaynila (University of the City ofManila),Manila, Philippines.
Published: September 2023

Deep learning has revolutionized the field of neural network models, offering limitless applications in various do- mains. This study focuses on Transfer Learning (TL), a technique leveraging pre-trained deep learning models trained on large datasets for image classification tasks. Specifically, this research explores the effectiveness of various transfer learning models in three medical image datasets: Alzheimer’s MRI images, Chest CT-Scan images, and Chest X-ray images. The main objective of this study is to assess and compare the performance of various TL models, including MobileNetV2, ResNet50, Xception, and InceptionV3, on the three medical image datasets. Additionally, a customized Convolutional Neural Network (CNN) model is developed to compare its performance against the pre-trained TL models. Each model was trained and evaluated on the three medical image datasets. The performance of the TL models was compared in terms of accuracy and training time. The results of this study revealed that ResNet50 consistently outperforms other TL models, demonstrating accurate predictions at the expense of longer training times. MobileNetV2 and InceptionV3 exhibit the fastest training times across all datasets, but they demonstrate poorer performance in certain datasets. The developed CNN model performs poorly in terms of accuracy and tends to overfit, indicating that creating a CNN model for medical image classification is not feasible in this study. The findings of this study offer valuable insights into the performance of TL models in medical image datasets. Researchers can utilize this information to make informed decisions when selecting TL models for medical imaging applications. Understanding the strengths and weaknesses of different TL models enhances the potential for accurate and efficient medical image classification. The insights gained from this study contribute to researchers’ understanding of selecting transfer learning models for medical imaging applications, aiding in the advancement of medical image analysis and diagnosis.
Puzzare di freddo
Authors: Bellina Massimo
Published: September 2023

Alcuni lettori ci chiedono quale sia l’origine dell’espressione, diffusa in area napoletana, puzzare o puzzarsi di freddo o dal freddo.
Human action classification using CNN by encoding time series skeleton-based data as images
Authors: Imran Muhammad Mu'az , Idris Azam Che , Silva Liyanage Chandratilak De , Yassin Hayati
Published: September 2023

Microsoft Kinect camera can capture depth images of the subject during surveillance of Human Activity Recognition (HAR) and subsequently obtain the skeletal data. Several studies have attempted to use and analyse human actions based on skeletal data and other complex feature representation extraction methods. Most authors have proposed obtaining Spatio-temporal information as one of the extraction methods. Therefore, this study automatically extracts the Spatio-temporal information from the skeletal data by using an Imaging time series (ITS) method called Recurrence Plots (RP) to transform the skeleton joint coordinates into 2D images. The raw data are preprocessed and partitioned into three-channel matrices (R, G, B) before applying the principal component analysis (PCA). The generated RP images are used as input to Convolutional Neural Network (CNN) to distinguish between different activities. The proposed method uses the UTD-MHAD dataset for benchmarking and shows that our approach outperforms previous studies with a maximum accuracy of 92.6%. 
DESAFIOS NA GESTÃO PÚBLICA NO PROCESSO DE GESTÃO EM SAÚDE: UMA REVISÃO DE LITERATURA.
Authors: Cancian Mario , Cavalcante Wylma Tenorio , Pinho Silvia Teixeira de
Published: September 2023

A gestão pública em saúde também busca promover a equidade e a participação social, buscando atender as necessidades e demandas da população de maneira justa e democrática. Além disso, busca-se também a melhoria contínua dos serviços, a promoção da saúde e a prevenção de doenças. O objetivo do presente estudo foi identificar os erros e dificuldades no ambiente de trabalho hospitalar na gestão pública. Trata-se de uma revisão sistemática de literatura que aborda os temas “gestão pública em saúde” nas plataformas de artigos científicos Google Acadêmico e Scielo publicados no período de 2001 a 2023. Os resultados  sobre as dificuldades na gestão pública em saúde são relacionados a escassez de recursos financeiros, muitos gestores públicos enfrentam dificuldades na obtenção de recursos suficientes para financiar os serviços de saúde, fragmentação e falta de integração,o sistema de saúde pública muitas vezes é fragmentado, com diferentes governos e agências responsáveis por diferentes aspectos, como atenção primária, hospitais e programas de prevenção alta rotatividade de profissionais a gestão pública em saúde muitas vezes enfrenta problemas na retenção de profissionais qualificados, devido à baixa remuneração, más condições de trabalho e falta de perspetivas de carreira, corrupção e má gestão dos recurso a corrupção são problemas comuns na gestão pública em saúde, desvio de verbas, nepotismo, contratos super faturados e falta de transparência comprometem a eficiência e a qualidade dos serviços, além de minar a confiança da população no sistema de saúde, desigualdades regionais dificuldades na gestão pública em saúde também podem ser observadas na desigualdade no acesso aos serviços de saúde entre as diferentes regiões de um país. Destacamos que a gestão pública em saúde requer uma abordagem multidisciplinar, com a participação ativa de diferentes atores, como médicos, enfermeiros, gestores, pesquisadores e pacientes. Conclui-se que, o maior desafio é a falta de estrutura médica e que a colaboração entre esses diferentes profissionais e setores é fundamental para garantir uma gestão mais eficiente e eficaz. Além disso, é fundamental que esses recursos sejam distribuídos de maneira equitativa, garantindo o acesso aos serviços de saúde a todos, independentemente de sua renda ou local de residência,a transparência na gestão pública em saúde também é fundamental.
TRANSTORNO DE PERSONALIDADE ANTISSOCIAL: UMA REVISÃO INTEGRATIVA ACERCA DOS FATORES GENÉTICOS E AMBIENTAIS DO DIAGNÓSTICO
Authors: Marsura Ana Maria , Rangel Lays Ribeiro , Guimarães Eugenya da Costa , Coimbra Rafael Borges , Ferreira Vitória Macedo Falcão , Silva Geovanna Oliveira , Mendonça Tarso Braz , Mendonça Tiago Braz , Reis Paulo Victor Dias dos , Lourenço Pedro Henrique , Pardin Edinho Pereira , Hammerschmidt Rafaela Maia
Published: September 2023

O Transtorno de Personalidade Antissocial é uma condição psiquiátrica complexa caracterizada por padrões persistentes de desrespeito pelos direitos dos outros, comportamentos impulsivos, falta de empatia e remorso, além de tendências para a manipulação e a enganação. A compreensão do Transtorno de Personalidade Antissocial envolve a análise cuidadosa de uma ampla gama de fatores, incluindo fatores genéticos e ambientais, que desempenham um papel fundamental no seu desenvolvimento e diagnóstico. O presente artigo consiste em uma revisão integrativa, no qual tem como objetivos discorrer acerca dos fatores genéticos e ambientais que influenciam no diagnóstico do transtorno de personalidade antissocial, mediante considerações acerca da patologia e da interseção entre eles, no intuito de ampliar os conhecimentos da sociedade, de estudantes e profissionais da área acerca do tema em questão. Trata-se de uma revisão integrativa, na qual foi realizada uma pesquisa dos tipos básica, qualitativa, exploratória e bibliográfica, nas bases de dados. Os fatores genéticos desempenham um papel fundamental no desenvolvimento do Transtorno de Personalidade Antissocial. Estudos científicos têm apontado que a predisposição genética é um dos componentes-chave para a compreensão desse transtorno complexo. Os fatores ambientais exercem um papel de extrema importância no desenvolvimento do Transtorno de Personalidade Antissocial. Eles constituem influências externas que moldam a maneira como os indivíduos com o transtorno interagem com o ambiente que os cerca e influenciam a manifestação de seus comportamentos. Em suma, é possível concluir que a interseção entre fatores genéticos e ambientais é essencial para compreender o Transtorno de Personalidade Antissocial.
Tipos de lasers e suas aplicações na clínica geral odontológica e odontopediátrica: revisão de literatura
Authors: Oliveira Koriny Gurgel , Machado Fabrício Campos
Published: September 2023

Os lasers são classificados em baixa potência e alta potência. Podem ser usados em diversas áreas da odontologia, a sua aplicabilidade na odontopediatria vem ganhando espaço, como por exemplo em preparos cavitários, cirurgias de freio lingual e labial, ortodontia e biomodulação de lesões orais. O objetivo deste trabalho foi levantar os tipos de laser empregados no atendimento de crianças, e a relevância de seu uso na vivência clínica. Foi realizada uma revisão integrativa da literatura, por meio de buscas eletrônicas nas seguintes bases de dados: BVS, LILACS, SciELO e PubMed entre os anos de 2018 a 2023 com as palavras chaves “laser”, “laserterapia” e “odontopediatria” isoladas e associadas por meio do operador boleano “e”, bem como seus correspondentes em inglês. Foram selecionados, um total de 18 artigos após o uso dos critérios de inclusão e exclusão. Das pesquisas realizadas, a aplicabilidade dos lasers de alta potência foram usados para a realização cirúrgicas, frenotomias lingual e labial apresentando uma melhora significativa quando comparado com as técnicas tradicionais além da realização de preparos cavitários. Por outro lado, os lasers de baixa potência, em seus diversos comprimentos de onda podem ser usados como adjuvantes na regeneração óssea, cicatrização e fotobiomodulação em lesões orais, além da sua utilização como tratamento adjuvante em tratamentos ortodônticos. Dessa forma, conclui-se que os lasers de baixa e alta potência são opções consideráveis para a utilização no cotidiano do cirurgião-dentista e odontopediatras trazendo benefícios relevantes para a prática clínica.
Description of Student Communication and Attention Patterns In Islamic Religious Education Learning
Authors: Rismawan  , Arnold Yasin Mol  , Aliyu Ibrahim Musaddad
Published: September 2023

Purpose of the study: The purpose of this research is to describe the pattern of communication and the attention of students in learning Islamic religious education. Methodology: The type of research used is quantitative research, the population in this study is students of Senior High School, the sample to be used in this study is determined by purposive sampling method, the instrument used is questionnaire and the data analysis techique is using statistic descriptive Main Findings: The results of this study are that student communication is more dominant, good and also the attention of students is also very good in the process of learning the Islamic religion Novelty/Originality of this study: The novelty of this research is to describe the communication skills and attention of students in the learning process of Islamic religion. Suggestions for further research are to find a link between communication skills and students' attention in the learning process so that it becomes even better.
Increasing Students' Cognitive Absorption Through Remedial Learning in Physics
Authors: Asis Asmawati , Ching Chin Peng , Suttiwan Witsanu
Published: September 2023

Purpose of the study: To determine whether there is an increase in junior high school students' absorption of physics subjects after participating in remedial learning. Methodology: This type of research is classroom action research. Junior high school students as subjects subjected to action in this study. The sampling technique in this study used purposive sampling. The instruments used in this study were diagnostic tests, final tests, observation guidelines. The collected data were analyzed using quantitative analysis. Main Findings: The application of remedial learning has been able to help students increase their cognitive absorption from one cycle to the next. Novelty/Originality of this study: The novelty of this research is that teachers can find out one of the learning methods to increase students' absorption and add insight into learning strategies.
KUZNETSK TELEUTS IN THE DIARIES AND NOTES OF HISTORIANS AND ETHNOGRAPHERS: ON THE CHARACTERISTICS OF A LOCAL ETHNIC GROUP
Authors:   The Russian Academy of Sciences N.N. Miklouho-Maklay Institute of Ethnology and Anthropology, Batyanova Yelena P.
Published: September 2023

The article attempts to describe the cultural and ethnic distinctiveness of the Kuznetsk Teleut who represent a territorially separate group of Teleuts, one of the smaller indigenous peoples of Siberia. It traces the specifics of the local development of this group in the 20th-21st centuries. The research draws primarily on archival sources containing records and fieldnotes of ethnographers studying the Altai region, such as A.V. Anokhin, P.I. Karal’kin, and A.G. Danilin, and the own fieldwork materials of the author.
STUDENT ETHNOGRAPHIC / ETHNOLOGICAL EXPEDITIONS OF NATIONAL UNIVERSITIES: MEMORIALIZATION AND REFLECTION
Authors:   Dostoevsky Omsk State University, Chernova Irina V.
Published: September 2023

The purpose of the study is to identify the main trends in historiography related to the process of organizing student ethnological / ethnographic expeditions and to determine their role in the formation of a modern student researcher. The study is based on published academic essays, materials of visual and online projects as well as sources that reflect personal experiences of involvement in student expeditions. The novelty of the study is derived from the need to assess the mechanisms of memorialization and perception of students’ own professional activity.
USING THE EDUCATIONAL GAME “MEMO” TO DEVELOP SOFT SKILLS IN UNIVERSITY STUDENTS
Authors:   Altai State Pedagogical University, Lebedeva Ksenia S.
Published: September 2023

This paper examines the issues and methods of developing soft skills in university students. The author provides an analytical review of research in this area, comparing and highlighting the most effective methods of formation of the studied skills. One such method is educational games; the author shares examples of using a game called “Memo” in teaching a course on pedagogy, making conclusions about the effectiveness of such games in developing soft skills.
SYNERGETICS OF AXIOLOGICAL PRIORITIES OF RUSSIAN TEACHERS OF THE EARLY TWENTIETH CENTURY
Authors:   Glazovsky State Pedagogical Institute named after V.G. Korolenko, Zakharishcheva Marina A.
Published: September 2023

The historical and pedagogical process is considered from the perspective of a synergetic methodological approach, which allows the author to show the polyphony and non-linearity of pedagogical systems and values of teachers working in the first decade of Soviet Russia. The research material used includes the works of famous teachers, which most clearly outlines their axiological priorities. Using the methods of analysis and synthesis, systematization and generalization, the author shows the potential of a synergetic approach to analyzing historical development of education in Russia as seen during a period of critical change in the early twentieth century.
FOREIGN LANGUAGE LEARNING FOR PROFESSIONAL EDUCATION INSTITUTE STUDENTS ACCORDING TO BLENDED LEARNING MODEL
Authors:   T.F. Gorbachev Kuzbass State Technical University, Dolgova Natalia I.
Published: September 2023

The article deals with the issues of teaching a second foreign language (German) for students of the Institute of Professional Education according to the model of blended learning. The purpose of this article is creation and implementation of the author’s electronic course “German for PEI students”, created in the LMS Moodle platform, for implementation of blended learning. The efficiency consideration of the of the application of the blended learning model in the process of teaching a second foreign language is studied.
PEDAGOGICAL CONDITIONS AND CAPABILITIES FOR DEVELOPING A RESPONSIBLE ATTITUDE TO DECISION-MAKING IN FUTURE OFFICERS
Authors:   Military Educational and Scientific Center of the Air Force “N.E. Zhukovsky and Yu.A. Gagarin Air Force Academy”, Dorosh Nadezhda V. , Korobov Alexey S. ,   Military Educational and Scientific Center of the Air Force “N.E. Zhukovsky and Yu.A. Gagarin Air Force Academy”, Chervinskiy Vladislav G. ,   Military Educational and Scientific Center of the Air Force “N.E. Zhukovsky and Yu.A. Gagarin Air Force Academy”
Published: September 2023

The article identifies the pedagogical capabilities necessary for developing a responsible attitude to making managerial decisions in future officers. These capabilities, in turn, help to outline the pedagogical conditions in a military university that ensure effective development. The results of experimental research demonstrate how well-targeted use of pedagogical conditions and capabilities of a military university makes it possible to increase the level of managerial responsibility of cadets.
SCIENTIFIC AND METHODOLOGICAL SUPPORT OF UNIVERSITY LIBRARIES AS A FACTOR IN PREPARING STUDENTS FOR HOMEROOM TEACHER RESPONSIBILITIES
Authors:   Novosibirsk State Pedagogical University, Lavrentyeva Zoya I.
Published: September 2023

The article explores the availability in university libraries of scholarly and methodological literature needed to prepare students for work as homeroom teachers. By analyzing collections of scholarly and methodological literature, the author identifies the dynamics of educational issues discourse, shows the correlation between educational content at different stages of development of the country, identifies the conditions for using accumulated library sources in training homeroom teachers. In conclusion, the author determines the prospects of scolarly and methodological support for training homeroom teachers.
IMPLEMENTING THE SYSTEMATIC ACTIVITY APPROACH IN DISTANCE LEARNING: FOREIGN LANGUAGE LESSONS
Authors:   Immanuel Kant Baltic Federal University, Mirkina Yulia Z. , Molchanova Anna S. ,   Immanuel Kant Baltic Federal University
Published: September 2023

This paper addresses aspects of planning and structuring foreign language lessons within the framework of the systematic activity approach in vocational education. The authors give an overview of the main didactic principles of the systematic activity approach and show the necessity of their correlation with the content of professional education. The examples of various assignments at different stages of a foreign language lesson illustrate how the principles of the studied approach could be implemented.
READINESS FRAMEWORK OF FUTURE DESIGNERS TO DEVELOP AND SUPPORT PROJECTS IN THE PRODUCTION SECTOR
Authors:   Siberian Federal University, Filipskaya Irina V.
Published: September 2023

The definition of the readiness structure allows us to identify criteria and indicators of the readiness of future designers to develop and support design projects in the production sector. The article analyzes the proceedings of scientists on the definition of the concepts of “readiness for professional working”, “readiness for project working” and the description of components of the structure of readiness for professional and project working. Using a comparative analysis of approaches to determining the component structure of readiness and the specifics of professional work in the field of design, the author identifies the framework components of the readiness of future designers for project work.
HOW LONELINESS AND SELF-ATTITUDE PRESENT IN UNIVERSITY STUDENTS
Authors:   Altai State Pedagogical University, Skorlupina Olesya A.
Published: September 2023

The article deals with the problem of self-attitude and the experience of loneliness in student age. The data of an empirical study of this problem are presented. It is shown that self-attitude and the experience of loneliness in students of different courses of study have their own characteristics. There is evidence of an existing relationship between the level of subjective feeling of loneliness and self-attitude among students.