bluuebunny/crossref_metadata_2025 huggingface dataset:
Edge impulse-based convolutional neural network for Hand Posture Recognition
Authors: Gui Yiwei
Published: February 2024

Hand Posture Recognition (HPR) plays a crucial role in enabling effective human-computer interaction, particularly for individuals with hearing disabilities. The study compares five models, including MobileNetV2 96x96 0.35, MobileNetV1 96x96 0.25, MobileNetV1 96x96 0.1, self-designed Network 1, and self-designed Network 2, based on the Sbastien Marcel Static Hand Posture Database. Evaluation metrics - infserencing time, peak RAM usage, flash usage, and accuracy - are used to analyze the performance. The experiment workflow for each model comprises five major steps. Firstly, a random selection of 120 images from the Sbastien Marcel Static Hand Posture Database is converted to JPG format. Then, the images are divided into 80% training data and 20% testing data. Subsequently, the original images are normalized, and features are extracted for further processing. Subsequently, the models are individually trained using the preprocessed data, optimizing their parameters. Finally, the trained models are evaluated using the testing data set to assess their performance in hand posture recognition. The results indicate that MobileNetV2 96x96 0.35 achieves the highest accuracy of 96.69% while consuming fewer hardware resources compared to other models. MobileNetV1 96x96 0.1 demonstrates the lowest inferencing time and peak RAM usage, making it suitable for real-time applications. Furthermore, self-designed Model 1 exhibits the lowest flash usage, making it a viable option for resource-constrained devices. This study provides valuable insights into the selection of CNN architectures for HPR, offering guidance for practitioners to choose models based on specific application requirements.
Research advanced in the integration of federated learning and reinforcement learning
Authors: Li Chengan
Published: February 2024

Reinforcement learning (RL) and federated learning (FL) are two important machine learning paradigms. Reinforcement learning is concerned with enabling intelligence to learn optimal policies when interacting with an environment, while federated learning is concerned with collaboratively training models on distributed equipment while preserving data privacy. In recent years, the fusion and complementarity of reinforcement learning, and federated learning have attracted increasing research interest, providing new directions for the development of the machine learning community. Focusing on the integration of reinforcement learning and federated learning, this paper introduces in detail the latest technological developments in the integration of reinforcement learning and federated learning, and discusses the main challenges, existing methods and future directions of this intersection. Specifically, based on the introduction of classical reinforcement learning and federated learning. In addition, this document introduces cutting-edge results on the integration of reinforcement learning and joint learning and discusses the problems and future directions of the integration.
Performance of convolutional neural networks on CIFAR and Dog Breed classification dataset
Authors: Bu Yang , Xiong Weitong , Zhu Lingfei
Published: February 2024

This research aims to study the deep learning applications in image recognition and classification tasks. The advantages and limitations of deep learning are explored by analysing existing deep learning algorithms and their applications on tasks such as using images to do classification, image segmentation, and target detection. In the experimental part, this paper evaluates the performance of deep learning in image recognition by using classical neural network models, including training and testing models on a large size of image datasets. The results show that neural network has good classification and detection capabilities in image recognition tasks and also achieves good results for image segmentation tasks. However, the model training process of shallow neural network models is time-consuming and performs poorly for small-scale datasets. Based on these situations, this paper proposes some optimization strategies to achieve high performance and efficiency of neural networks in image recognition and analyze the performance differences between different strategies .
Using Preference Cards to Support a Thoughtful, Evidence-based Orthopaedic Surgery Practice
Authors: Bellaire Laura L. , Nichol Peter F. , Noonan Kenneth , Shea Kevin G.
Published: February 2024

Introduction:

When orthopaedic surgeons begin or relocate their careers, they must communicate effectively about their instrumentation and equipment needs. ‘Preference Cards’ or ‘Pick Lists’ are generated by and for individual surgeons at the time of hire and can be updated over time to reflect their needs for common cases. Currently, such decisions are made without formal guidance or preparation.

Body:

Surgeons must consider and plan for their operating room needs. Health system and industry factors affect these decisions, as do surgeons' unique interests, preferences, and biases. Orthopaedic surgeons currently face challenges: formal education is deficient in this space, material and reprocessing costs are not transparent, relationships and contracts with industry are complex, and few health systems have mechanisms to support preference card optimization. This complex landscape influences utilization decisions and leaves opportunities for integration, collaboration, and innovation.

Choices about instrument and resource utilization in the OR have wide-reaching impacts on costs, waste generation, OR efficiency, sterile processing, and industry trends. Surgeons and their teams have much to gain by making intentional choices and pursuing both individual and systematic improvements in this space.
Exploring the Impact of TiO2 and MgO Nanoparticles on the Mechanical and Topographical Characteristics of Glass Fiber Reinforced Polymer (GFRP) Composites with Varied Lay-up Sequences: A Taguchi Analysis
Authors: A Somaiah , B Anjaneya Prasad , N Kishore Nath
Published: February 2024

A revolutionary composite material, blending Glass Fiber Reinforced Polymer (GFRP) with advanced nanofillers like TiO2 and MgO, showcases remarkable versatility in various industries due to its unique properties. The process involves precise control of key factors, including fiber stacking sequence (F.S.S) and nanofiller integration (MgO and TiO2). The vacuum bagging process is employed in the production of nanocomposite laminates. Experimental studies have been conducted to assess the performance of composites with and without nanofillers, with a specific focus on crucial mechanical properties, namely ultimate tensile strength (U.T.S), flexural strength (F.S), impact strength (I.S), and hardness (H). The Taguchi L9 orthogonal array design optimizes parameters and enhances mechanical properties. Comparisons reveal significant improvements with nanofillers, including a 31.96% increase in ultimate tensile strength and a substantial 68.43% enhancement in flexural strength. ANOVA results highlight the critical impact of fiber stacking sequence on ultimate tensile strength (63.65%), flexural strength (65.70%), and impact strength (9.30%), while nanofillers play a lesser role, contributing 11.71% to ultimate tensile strength, 2.66% to flexural strength, and 3.61% to impact strength. Notably, in composite hardness, nanofillers play a more significant role, contributing 39.22%, while the influence of fiber stacking sequence is lower at 3.29%.
Quality of life among patients with gastroesophageal reflux disease at Tuyen Quang general Hospital in 2023
Authors: Vu Thi Thu Ha , Tran Ngoc Duc , Vu Thi Thu Huong
Published: February 2024

Objectives: To assess the quality of life among patients with gastroesophageal reflux disease at Tuyen Quang General Hospital in 2023.
Research participants and methods: Cross-sectional descriptive study was conducted with 200 patients from March 2023 to June 2023. The Quality of Life in Reflux and Dyspepsia patients (QOLRAD) was used to interview patients for gastrointestinal examination and endoscopy at Tuyen Quang General Hospital.
Results: The average quality of life score among patients was 4.33 - 4.46. In which all fields were at a good level, not too different from the bad level, the average score in the item eating/drinking (4.33), the items of sleep disorders (4.36), the item of emotion (4.39), the item of physical/social (4.39), vitality domain (4.46).
Conclusion: The quality of life of patients with gastroesophageal reflux disease at Tuyen Quang General Hospital in 2023 is at a good level in all items.
A study to examine the relationship between mothers’psychosocial status and pregnancy outcome
Authors:   Department of Nursing, Clinical Instructor, Maharashtra University of Health Sciences, Nashik, India, Patharkar Minal Milind
Published: February 2024

Introduction: Pregnancy is the most wonderful experience of a woman’s life. A mother’s physical fitness is just as important as her mental health. A non-experimental and correlational study was conducted to examine the relationship between mothers’ psychosocial status and pregnancy outcome among 50 antenatal mothers in their third trimester. The aim: of the study is to assess the psychosocial status of antenatal care (ANC) mothers, assess the pregnancy outcome, and find out the correlation between psychosocial status and pregnancy outcome. Result: In this study, using the ALPHA scale to assess the psychosocial status of antenatal mothers, the majority of them had a higher psychosocial score, and some had a middle psychosocial score, but none had a low psychosocial score. Conclusion: From this study, we conclude that there was an association between psychosocial status and pregnancy outcome.
Uterine rupture in nulliparous woman without risk factors:a case report and literature review
Authors:   Department of Obstetrics and Gynecology, San Gerardo Hospital, University of Milan-Bicocca, Monza, Italy, Seca Marta , Selvaggia Bettoni Gaya ,   Department of Obstetrics and Gynecology, Bolognini Hospital, ASST Bergamo est Seriate, Bergamo, Italy, Paola Fenili ,   Department of Obstetrics and Gynecology, Bolognini Hospital, ASST Bergamo est Seriate, Bergamo, Italy, Francesco Clemente ,   Department of Obstetrics and Gynecology, Bolognini Hospital, ASST Bergamo est Seriate, Bergamo, Italy, Patrizia D’Oria ,   Department of Obstetrics and Gynecology, Bolognini Hospital, ASST Bergamo est Seriate, Bergamo, Italy, Paola Algeri ,   Department of Obstetrics and Gynecology, Bolognini Hospital, ASST Bergamo est Seriate, Bergamo, Italy
Published: February 2024

Objective: The aim of this study was to summarize the main features of spontaneous uterine rupture in primigravid patients before the onset of labor, emphasize the possibilities of therapeutic conduct, and offer points of reflection on the post-rupture management. Methods: We performed a literature review of all the individual case reports, retrospective case series, and reviews concerning uterine rupture in peer-reviewed journals from January 1975 to October 2021. Results: The diagnosis of uterine rupture was commonly made by abdominal pain, with or without concomitant nausea and vomiting. Uterine ruptures occur more frequently at the end of pregnancy or in the third trimester. The most frequently involved site is the uterine cornua followed by the posterior wall of the uterus. Other described cases identify the broad ligament, uterus sacral ligament, lower uterine segment, and anterior wall as possible points of rupture. The most frequently used suturing technique is the repair of the breach in two layers. Conclusion: Uterine rupture is an extremely rare obstetric emergency, correlated to life-threatening consequences for both the newborn and the woman. Considering the maternal and fetal risks, a tempestive diagnosis is mandatory.
Large anechogenic “Holes” in the uterus: The utilityof contextual combination of ultrasound and hysteroscopy
Authors:   Department of Obstetrics and Gynecology, Bolognini Hospital, ASST Bergamo EST, Seriate, Bergamo, Italy, Algeri Paola , Spazzini Maria Donata ,   Department of Obstetrics and Gynecology, Treviglio Hospital, ASST Bergamo Ovest, Treviglio, Bergamo, Italy, Pinna Nina ,   Department of Oncology, San Carlo Clinic, Paderno Dugnano, Milan, Italy, Seca Marta ,   Department of Obstetrics and Gynecology, San Gerardo Hospital, University of Milano-Bicocca, Monza, Monza e Brianza,Italy, Tomaselli Tiziana ,   Department of Obstetrics and Gynecology, Treviglio Hospital, ASST Bergamo Ovest, Treviglio, Bergamo, Italy, Campanile Garruto Riccardo ,   Department of Obstetrics and Gynecology, Treviglio Hospital, ASST Bergamo Ovest, Treviglio, Bergamo, Italy, Villa Antonella ,   Department of Obstetrics and Gynecology, Treviglio Hospital, ASST Bergamo Ovest, Treviglio, Bergamo, Italy
Published: February 2024

Cystic adenomyosis is a rare occurrence, especially in young patients. We report a challenging case of a 44-year-old African patient, in which the ultrasound described a large bilobate an echogenic cyst in the myometrium. The combination of ultrasound, contextual hysteroscopy, and subsequent magnetic resonance imaging helped to clarify the case, reducing the risk of complications for the patient, potentially due to misdiagnosis.
Hubungan Mutu Pelayanan Kefarmasian Terhadap Keberhasilan Berobat Pasien Diabetes Melitus (DM) Di RSUD Konawe Selatan
Authors: Yulianti Siska , Hamiru La Ode , Lolok Nikeherpianti , Baco Juliana
Published: February 2024

Keberhasilan terapi DM terhadap pengobatan sangat berperan dalam kontrol glukosa darah pasien DM. Pelayanan kefarmasian di rumah sakit merupakan bagian yang tidak terpisahkan dari sistem pelayanan kesehatan Rumah Sakit yang berorientasi kepada pelayanan pasien, pelayanan sediaan farmasi, alat kesehatan, dan bahan medis habis pakai yang bermutu dan terjangkau bagi semua lapisan masyarakat termasuk pelayanan farmasi klinik Pemberian obat bertujuan untuk mencapai hasil yang dapat meningkatkan kualitas hidup pasien Oleh karena itu, dalam penggunaan obat diperlukan pertimbangan yang tepat agar penggunaannya efektif dan efisien..  Penelitian ini bertujuan Untuk mengetahui hubungan mutu pelayanan kefarmasian dengan kepatuhan berobat pasien diabetes melitus di Intalasi rawat inap RSUD Konawe Selatan. Jenis ini adalah penelitian kuantitatif dengan menggunakan desain penelitian cross sectional. Jumlah populasi penelitian ini adalah 89 orang, Metode yang digunakan yaitu total sampling. Metode analisis menggunakan distribusi frekuensi, Chi squere dan Koefisien Ph.i Hasil penelitian ada hubungan antara keadaan fisik dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan. Ada hubungan antara ketanggapan dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan. Ada hubungan antara kehandalan dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan. Ada hubungan antara jaminan dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan. Ada hubungan antara peduli dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan.
Advancing Interview Preparation: An AI-driven Approach
Authors:   Department of Computer Engineering, Sinhgad College of Engineering-Vadgaon, Pune,  Maharashtra, India, Pawar Dr. Suvarna
Published: February 2024

This research paper presents a transformative approach to interview preparation through the integration of cutting-edge artificial intelligence and personalized learning techniques. In today's competitive job market, traditional methods of interview readiness often lack the immediacy and tailored support needed for success. Addressing this gap, our platform utilizes advanced AI algorithms to analyze user responses, offer real-time feedback, and dynamically adjust question difficulty based on performance. By prioritizing user-centric design and ethical considerations, our research explores the development, implementation, and evaluation of this innovative solution. Insights from user feedback and performance metrics underscore the platform's effectiveness in enhancing interview skills and fostering confidence among job seekers. This paper contributes to the broader discourse on AI-driven learning technologies and their potential to empower individuals in navigating the complexities of professional advancement. Key Words: Interview Preparation, Artificial Intelligence, Natural Language Processing, Personalized Learning, Skill Development.
Kwartalnik Nowy Napis #20
Authors: Baran Justyna , Ciemiera Katarzyna , Goczał Ewa , Kudyba Wojciech , Subocz-Białek Paulina
Published: February 2024

Teoretycy barokowego konceptu, „dowcipu”, utrzymują, że jest on „ruchem myśli – ruchem, czyli życiem”, wysiłkiem łączenia przeciwieństw (concors discordia), mnożenia celnych skojarzeń, które „dąży do osiągnięcia zdziwienia, zaskoczenia niesamowitym i wciąż zaskakującym światem”. Dopiero dziwiąc się światu, można go pełniej zamieszkiwać, bo to właśnie zaskoczenie wytrąca z automatyzmu percepcji i zmusza ciągle do przekraczania językowych oraz wyobrażeniowych schematów. Koncept tyleż zamyka (bo komplikuje), ile otwiera (bo poszerza pole poetyckiej wrażliwości). Przez filtr konwencji nie tyleż oddala od rzeczywistości, ile do niej zbliża, ponieważ wymusza szukanie nowych połączeń słowa z konkretem, w ruchu mnożenia metafor pobudza do nazywania wciąż na nowo, „a przecież każdy taki wysiłek wykazuje, że rzecz – mimo iż nazywana – sterczy niezależna i nienazwana, poza językiem sterczy, wystaje jak kamienie z rzeki”.
Tạo kháng thể IgG thỏ kháng IgG người
Authors: Thái Thị Tuyết Trinh  , Trần Thị Cẩm Tú  , Lê Thị Phương Thảo  , Nguyễn Hữu Hùng
Published: February 2024

Bài báo này trình bày kết quả tạo và tinh chế IgG thỏ kháng kháng nguyên IgG người bằng các phương pháp như gây đáp ứng miễn dịch cho động vật bằng cách tiêm trong da, tinh sạch kháng thể IgG bằng phương pháp tủa với ammonium sulphate 45% và phương pháp sắc kí ái lực qua cột protein G. Ngoài ra, bài báo còn đề cập đến các phương pháp kiểm tra hiệu quả của quá trình gây đáp ứng miễn dịch như phương pháp khuếch tán kép trên thạch (Ouchterlony) và Western blot. Mục đích của việc nghiên cứu là tạo và tinh sạch kháng thể IgG thỏ kháng kháng nguyên IgG người đạt độ tinh sạch cao, làm tiền đề cho việc phát triển qui trình sản xuất kháng thể tinh sạch trong nước cũng như ứng dụng trong các kit chẩn đoán nhằm phục vụ cho nghiên cứu khoa học và xét nghiệm phát hiện bệnh. Kết quả nghiên cứu thu nhận được khoảng 80mg kháng thể IgG thỏ kháng IgG người tinh sạch, với độ sạch cao (ước tính > 95% khi phân tích bằng SDS-PAGE).
Aplicação do índice de vulnerabilidade socioambiental a desastres por meio de Sistema de Informação Geográfica (SIG):
Authors: Mattedi Marcos Antônio , Mello Bruno Jandir , Souza Cristiane Mansur de Moraes , Vicentainer Denis Augusto , Kormann Tanice Cristina
Published: February 2024

Objetivo do Estudo: Mapear e classificar a vulnerabilidade socioambiental das regiões do município de Blumenau (SC) aos desastres socioambientais (inundações, enxurradas e deslizamentos de terra) por meio da construção de um índice de vulnerabilidade socioambiental (SEVI) para os anos de 2000 e 2020.
Metodologia: O mapa IVSA foi desenvolvido a partir de uma análise multicritério com auxílio de Sistema de Informação Geográfica (SIG). Para o funcionamento do IVSA foi necessário a confecção dos índices da suscetibilidade ambiental (SA) e vulnerabilidade social (VS) para os anos de 2000 e 2010, posteriormente projetados para o ano de 2020. Os índices de SA e VS são cruzados numa Matriz de Impacto. Assim, constituiu-se os Mapas de Vulnerabilidade Socioambiental comparativos para os anos de 2000 e 2020.
Originalidade/Relevância: Desenvolvimento de uma metodologia de avaliação de vulnerabilidade socioambiental a desastres, que considera as questões do meio-físico natural local e capacidade de grupos sociais em resistir/responder aos desastres.
Principais Resultados: Os resultados apontam um aumento das ocupações irregulares em áreas de preservação permanente (APP), da degradação ambiental, da desigualdade social e consequentemente da população exposta ao risco. Em suma, o município apresenta um padrão de alta suscetibilidade e um exacerbado aumento da vulnerabilidade social, o que configura um cenário altamente vulnerável aos desastres socioambientais.
Contribuições: Avanços em pesquisas de avaliação e formulação de propostas de gestão integrada dos riscos e da resiliência nos municípios do Vale do Itajaí/SC/Brasil. Nesse contexto, é importante a compreensão dos cenários de maior impacto dos desastres socioambientais, como ferramenta de planejamento urbano e gestão dos riscos de desastres no município de Blumenau (SC).
NGO Resilience: Sustaining Education in Underprivileged Primary Schools Amidst the COVID-19 Pandemic in Bangladesh
Authors: Obaidullah Sharif
Published: February 2024

During the outbreak of COVID-19, all schools and universities in Bangladesh as well as around the globe were closed. For this reason, a large proportion of the disadvantaged students absented themselves from school. This study aims to gain insight into the actual state of underprivileged primary schools in Dhaka that are run by NGOs. Fundamentally, the study looked at how schools are adapting to change and what methods they are using for students interested in continuing their education. Results from qualitative research such as in-depth interviews with participants and FGDs are presented. According to the study, although they were forced to temporarily turn away from their education because of the pandemic, children in underprivileged institutions persevered with their schooling. The pandemic overall brought a massive hurdle to daily life, but people have gotten used to it. It seemed that when the schools closed low-income children would be hard hit. In reality, however, it wasn't nearly as bad as people feared. The study's findings would be extremely useful for gaining a deeper comprehension of the schools' initiatives and motivations amidst the pandemic.
IMPLEMENTATION OF CHANGES IN THE MINIMUM AGE FOR MARRIAGE FOR MEN AND WOMEN IN VIEW OF ISLAMIC LAW IN INDONESIA
Authors: Ingratubun Muhammad Husni , Hamid Muhammad Arfin
Published: February 2024

Objective: Indonesia is a constitutional state with a Muslim majority that uses Islamic law as a source of law which is then codified in law (taqnin al-ahkam). This was born marriage law, judicial law, religion, zakat law, and waqf law. After the enactment of Law no. 16 of 2019 concerning Marriage there are changes regarding the minimum age limit for marriage.
 
Methods: This type of research is empirical juridical in nature which in other words is a type of sociological legal research and can also be called field research, which examines the legal provisions that apply and what actually happens in society
 
Results: The results of this study concluded that there were many marriage dispensation applications to the Religious Courts. This is influenced by several factors, namely legal substance factors, educational factors and economic factors.
 
Conclusion: This research examines application of the marriage age limit must be updated in accordance with current Islamic law.
HIGH-PRECISION CYCLIC CORRELATION AS A BASIS FOR DETAILED PALEOCLIMATIC RECONSTRUCTIONS FOR THE CRIMEAN-CAUCASIAN REGION IN JURASSIC TIME
Authors: Gabdullin Ruslan R. , Syromyatnikov Kirill V. , Karpova Evgeniya V. , Kazurov Maksim D. , Puzik Aleksey Yu. , Badyanova Irina V. , Kazymov Konstantin P. , Merenkova Sofya I. , Badulina Natalya V. , Ivanov Aleksey V. , Migranov Iskander R.
Published: February 2024

An astrochronological (cyclostratigraphic) binding of the lithological and geochemical characteristics of the Jurassic deposits of the Mountainous Crimea and the Caucasus to the cycles of eccentricity of the Earth’s orbit is carried out, an analysis of the relationship between the established variations of climate and paleotemperature with the moments of coincidence of different-order cycles of eccentricity and their paleoclimatic characteristics is given. New data on paleotemperatures of the Southern Demerdzhi mountain section are presented.
IDENTIFICAÇÃO DE NECESSIDADES PALIATIVAS, CARACTERIZAÇÃO CLÍNICA E CAPACIDADE FUNCIONAL DE PACIENTES COM INSUFICIÊNCIA CARDÍACA
Authors: De Carvalho Neto Joaquim Jeronimo , Da Cruz Vitória Taise , Ogura Alex Yuiti , Seki Karla Luciana Magnani , Rigo Rosângela Silva , De Brito Carolina Figuerôa
Published: February 2024

O aumento do número de pacientes com insuficiência cardíaca devido ao envelhecimento da população e aos avanços no tratamento da doença ressalta a necessidade de uma abordagem mais abrangente no cuidado desses pacientes. Embora a insuficiência cardíaca seja uma doença com risco de morte súbita, é fundamental reconhecer que muitos pacientes enfrentam uma trajetória de doença crônica e debilitante. Objetivos: Este estudo buscou identificar pacientes com insuficiência cardíaca, acompanhados ambulatorialmente com necessidades de cuidados paliativos, analisando suas características clínicas e capacidade funcional. Método: para a identificação da necessidade de cuidados paliativos foi utilizado o Necpal (Necessidades paliativas), PPS (Palliative Performance Scale) que mede a capacidade funcional e o estado geral de pacientes e a ESAS (Edmonton Symptom Assessment System) que avalia a intensidade de nove sintomas principais, permitindo que os pacientes classifiquem a gravidade desses sintomas em uma escala numérica. Os participantes do estudo foram divididos em 2 grupos: Necpal + e Necpal -, a seguir foram comparados às características clínicas gerais, capacidade funcional e relato de sintomas. Na análise estatística para a comparação do perfil geral e clínico com as avaliações de Necpal aplicou-se os testes estatísticos de Mann-Whitney e para as variáveis categóricas o teste Qui quadrado, com o nível de significância de 5%. Resultados: Participaram do estudo 58 pacientes de ambos os sexos (36 homens e 22 mulheres), com média de idade de (59,79±11,97) anos. Na comparação clínica dos dois grupos estudados houve semelhança na distribuição de sexo (p=0,67); idade (p=0,91); fração de ejeção (p=0,06) e relativa preservação da funcionalidade (PPS>50%) (p= 0,16). O grupo Necpal + apresentou relato mais expressivo de sintomas: sonolência (p=0,04), náusea (p=0,02) e apetite (p=0,10). Considerações finais: Na amostra estudada houve indicação expressiva de necessidades paliativas e na comparação dos grupos estudados houve semelhança nas características demográficas e funcionalidade, com maior sintomatologia naqueles com indicação de necessidades paliativas.
PERSPECTIVAS CONTEMPORÂNEAS NO TRATAMENTO MULTIDISCIPLINAR DE DOENÇAS AUTOIMUNES
Authors: Lima Elaynne Jeyssa Alves , Dos Santos Márcia Mônica Borges , Lages Maria Gizelda Gomes , Teixeira Mirian Vieira , Sousa Ithalo Gomes Garcia , De Sousa Mirna Ribeiro Freitas , Melo Pablo Vitor Morais , Ferreira Maria Teresa da Silva , Gomes Andréia Pereira dos Santos , Delela Fernanda Crestina Leitenski , Lima Júnior Francisco de Paula Barroso , Da Silva Luiz Carlos Rodrigues , Garcia Adriana Fonseca , Dos Santos Clairton Edinei
Published: February 2024

Objetivo: Analisar as perspectivas contemporâneas no tratamento multidisciplinar de doenças autoimunes. Metodologia: Trata-se de uma ampla revisão da literatura, realizada em 2024 por meio da consulta às bases de dados LILACS e MEDLINE. Resultados: Os tratamentos variam conforme o tipo e gravidade da doença, incluindo terapias imunossupressoras, terapias-alvo, imunomoduladores e terapia celular personalizada. Destaca-se o papel crucial do PD-L1 na regulação da autoimunidade, com estratégias de imobilização in-situ mostrando eficácia. A modificação do N6-metiladenosina (m6A), regulação das citocinas IL-17, células-tronco mesenquimais e terapia transitória com células T CAR baseadas em mRNA são abordagens inovadoras. Além disso, o tratamento pode incluir opções farmacológicas, fisioterapia, acupuntura, jejum intermitente e correção da hipovitaminose D. Conclusão: As perspectivas contemporâneas no tratamento multidisciplinar de doenças autoimunes refletem avanços promissores, desde terapias inovadoras até abordagens não farmacológicas. No entanto, a necessidade de estudos contínuos e uma abordagem integrada destaca a complexidade dessas condições e a importância de cuidados personalizados para melhorar a qualidade de vida dos pacientes.
Pemanfaatan Trichoderma sp dan Aspergillus sp dalam Pengomposan Tandan Kosong Kelapa Sawit
Authors: Sakiah Sakiah , Arfianti Dina , Silalahi Alyuda B , Lesmana Indra
Published: February 2024

Pengembalian hara yang terangkut saat panen perlu dilakukan dengan cara mengembalikan biomassa kedalam tanah, salah satunya dilakukan dengan mengubah biomassa segar menjadi kompos. Penelitian ini bertujuan untuk menguji kemampuan isolat Trichoderma sp dan Aspergillus sp sebagai dekomposer dalam pengomposan tandan kosong kelapa sawit serta mengetahui karakteristik kompos yang dihasilkan. Penelitian menggunakan rancangan acak kelompok non faktorial, sebagai perlakuan yaitu jenis dekomposer terdiri atas 4 taraf yaitu P1 (100 % TKKS), P2 (100 % TKKS + Aspergillus sp 30 ml), P3 (100 % TKKS + Trichoderma sp 100 ml), P4 (100 % TKKS + Aspergillus sp 30 ml + Trichoderma sp 100 ml). Hasil penelitian menunjukkan perlakuan pemberian dekomposer berpengaruh tidak nyata pada parameter C, N, K dan rasio C/K kompos TKKS, tetapi berpengaruh nyata pada pada parameter kadar P kompos dan rendemen kompos. Pemanfaatan isolat Trichoderma sp dan Aspergillus sp dalam pengomposan TKKS belum mampu mengimbangi mikroorganisme indigenous yang terdapat didalam TKKS. Meskipun secara statistik perlakuan perbedaan dekomposer berpengaruh nyata terhadap kadar P kompos, namun kadar P kompos TKKS tanpa pemberian isolat lebih tinggi dari perlakuan lainnya. Untuk mendapatkan hasil kompos TKKS yang optimal, disarankan agar memanfaatkan mikroba indigenous yang bersumber TKKS tersebut.
Program for the development of digital competencies in teachers of the Stomatology career. Isla de la Juventud
Authors: Ivonnet-Gutiérrez Ennis , Peña-Méndez Aliana , Silva-Vázquez Felicia , Zaldívar-Carmenate Leonides , Vargas-Labrada Luisa Sucel
Published: February 2024

Introduction: information and communication technologies are important tools for training and communication. To facilitate their work in the educational system as a requirement for change in the profile of the education professional, teachers must develop suitable digital skills to implement in their teaching-learning process.
Objective: design a program for the development of digital skills in teachers of the Stomatology career of the Faculty of Medical Sciences of the Isla de la Juventud, 2022.
Methods: a descriptive study was carried out, from a methodological perspective based on the qualitative paradigm. The universe was made up of 150 teachers, of which 40 made up the sample. The theoretical level research methods were used: analytical-synthetic, inductive-deductive and historical-logical analysis; at the empirical level: documentary analysis, survey and specialist criteria.
Results: the need to train the teaching staff and guide the preparation of teachers in the appropriate use of computer techniques and resources, as well as in the preparation and development of virtual courses using the Moodle platform, was confirmed.
Conclusions: information and communication technologies are fundamental in the teaching-learning process. The development of digital competencies in teachers shows a low level of performance; the expressed limitations focus mainly on knowledge and domains in content creation, communication and collaboration.
Strategic planning and organizational performance of the Mypes of the manufacturing sector in the province of Cañete
Authors: Ancaya-Martínez María Del Carmen Emilia , Gonzales-Huaytahuilca Roxana Beatriz , Carire Soras Isabel , Ochoa-Tataje Freddy Antonio
Published: February 2024

The objective of this study was to determine the relationship between strategic planning and organizational performance of SMEs in the manufacturing sector in the province of Cañete, 2022. It was a quantitative, non-experimental, descriptive and correlational study. The sample included entrepreneurs from 325 MSEs. A survey was applied to collect information on the size, sector, organizational structure, strategic planning, and organizational performance of the MSEs, consisting of 24 items. According to the results, 60,9 % are microenterprises, 66,8 % are private, with a linear organizational structure (46,8 %). The value obtained was Rho= 0,902, indicating a perfect positive correlation between strategic planning and organizational development. As for the dimensions, the correlation was: organization (0,837), budget execution (0,897) and programmatic compliance (0,949). It is concluded that there is a significant correlation between strategic planning and the organizational performance of SMEs in the manufacturing sector in the province of Cañete in the year 2022.
A Case Report of Two Youthful Brothers: The Spine Combines with Multiple Butterfly Vertebrae and Hemivertebrae
Authors: Tian Xiaobing , Xie Weijie , Zhao Zhi
Published: February 2024

Butterfly vertebrae (BV) and Hemivertbrae (HV) are all rare congenital spinal abnormality and usually reported in the literature as an isolated finding. As far as the authors know, cases with multiple butterfly deformities and hemivertebra deformities of the spine are very rare. The condition of two brothers suffering from this disease at the same time has not been reported in the literature. We report two youthful brothers, the young brother, 14-year-old, who has butterfly vertebrae at T6-T11, L1, L3, and a hemivertebrae at L4; the old brother, 18-year-old, who has butterfly vertebrae at T5, T6, T8, T10, T11, T12, L1, L3, L4, L5, S1. They all have scoliosis and low back pain, and a 46, XY karyotype. The old brother performed TBX6 and APOB mutation.
A Study on Norovirus-Related Research
Authors: Zhang Yao
Published: February 2024

Norovirus is a major cause of viral diarrhea by foodborne infection. Its rapid mutation is mainly based on gene mutation, recombination. We will analyze from 4 aspects, structure and evolutionary characteristics, epidemic, main detection methods, current preventions. According to the study, pre-school children are vulnerable to norovirus each year in the child-care institutions. And the main detection is through fluorescent RT-PCR, and there are no approved vaccines or specific therapeutics to treat the disease.
Repair of Destroyed Liver Cells or Protection Liver Cells from Destruction by Silymarin and Minor Concentration of Vitamin E and Vitamin K
Authors: Ayyad Rezk R. , Nejm Ahmed M. , Hassan Yasser Abdel Allem , Ayyad Ahmed R.
Published: February 2024

The Liver is a major organ in the human body due to it play a great function of metabolism where it convert some of toxic compounds into un toxic also make the insoluble compounds more soluble and easy excrete from kidney. So, we must be keeping this (factory) organ in health state otherwise the more troubles in the life. Also, if this Liver has any dysfunction must be Repair quickly as soon as possible. Hence, the Silymarin and very small concentration of Vitamin E and Vitamin K must incorporated to the fatigue Liver or un healthy Liver.
Traditional and Modern Disaster Resistant House Construction Techniques
Authors: Kumar Vinod
Published: February 2024

A large portion of the wealth of any nation is invested in its built-up environment viz, housing, infrastructure, industrial and commercial facilities. The quality of this built-up environment, expressed in terms of durability, safety and functionality, is a determining factor for the quality of life and economic development of the society, and the competitiveness of its industry and services. Extensive loss of this wealth is caused by natural disasters that strike periodically. A natural disaster is an event of nature that causes sudden destruction, damaging the economy and social structure on a massive scale. The calamity results in a huge financial burden in terms of relief and rescue operations. All-round decline in production, unemployment, indebtedness as well as increased cost of goods and services are the other debilitating results of natural disasters. This research paper deals with the traditional as well as modern disaster resistant construction techniques to meet the aftermath of disasters. It examines the issue of damage to Reinforced Concrete Cement (RCC) buildings by underlying the necessity of adherence to building codes and standards. Some recent advances in housing technology are also highlighted.
Injury Prevention and Talent Retention: A Coach’s Role in Sustaining Athletic Potential in Young Athletes
Authors: Liu Siqi
Published: February 2024

This paper explores the multifaceted role of coaches in injury prevention and talent retention among young athletes. Acknowledging the interconnectedness of physical and psychological well-being, the study delves into the profound impact coaches wield on athlete behavior, performance, and the cultivation of a positive coaching environment. A detailed examination of existing research on injury prevention, talent dropout rates, and coaching strategies sets the foundation for understanding the challenges coaches face. The paper explores through key aspects, including the integration of injury prevention into training plans, maximizing available resources, overcoming resistance to change, and fostering individualized athlete engagement. By proposing practical solutions and preventive measures, this research contributes to the development of effective coaching methodologies, ensuring the sustained athletic potential of young talents.
NOTION OF HUMAN RIGHTS
Authors: Krivokapić Boris
Published: February 2024

The work consists of three parts. The first one deals with the term “human rights” and what is meant by it - a special concept, fundamental legally protected human rights and freedoms, specific legal solutions, what happens in practice, clearly defend human rights and freedoms that belong to specific persons i.e. groups, area of law that regulates human rights, a special subject taught in law schools, etc. After that here it is pointed out a fundamental difference between human rights and freedoms, as well as the distinction between human rights and some similar social phenomenom.
In the second part, it was pointed out that human rights are a very complex social phenomenon. Accordingly, an overview of their various dimensions - philosophical, ideological, political, economic, social, educational and legal is given.
The third part deals with the legal regulation as a mandatory part of human rights. Here it is emphasized that there are no human rights if they are not legally regulated and it is explained why this is so. It was pointed out that the legal regulation means that human rights are legally guaranteed, that their holders have a legal basis to request their free enjoyment and, if necessary, protection i.e. that, viewed from another angle, the obligations of the state and other entities are legal obligations, mandatory rules of conduct. In other words, non-compliance or violation of human rights is a violation of law as an objective normative order, which means that it entails legal liability. The author emphasizes that in terms of substance, when it comes to human rights, it is no longer issue of good will or discretionary assessment of respective entities, primarily states, but it is a system of legal rules of national and international law, which are intertwined and complementary.
PROTECTION OF COPYRIGHT IN THE DIGITAL WORLD
Authors: Diligenski Andrej , Prlja Dragan
Published: February 2024

In today’s digital world, in which the copyrights and intellectual property (music, pictures, movies...) are copied and replicated free of charge and in excellent quality over the Internet with tremendous speed, is almost every one of us confronted every single day with a complicated issue of copyrights. The territorial jurisdiction of the copyright law is facing new challenges in the digital world and above all on the Internet. Court practice review of the European Court of Justice and the German courts indicates legal problems in practice. Besides that, courts through interpretation of the European law provisions directly affect the protection of copyright in the digital world. This role of case practice in the creation of copyright protection contributes the fact, that in the digital world technical achievements are rapidly developing. On the other hand the political processes are extremely lengthy, so that the courts make their decisions quicker and create the law. Every day use of someone else’s copyright works by file sharing service providers or link setters opens questions of legal liability for the copyright infringement The use of Creative Commons licensed copyright works open up a new dimension in the implementation of copyright protection in the digital world.
ENTREPRENEURSHIP IN INSURANCE: THE IMPORTANCE AND LEGAL PRINCIPLES OF CORPORATE SOCIAL RESPONSIBILITY OF INSURANCE COMPANIES
Authors: Njegomir Vladimir , Petrović Zdravko
Published: February 2024

Entrepreneurship involves the exploitation of market opportunities that is based on ideas and innovation. The aim of entrepreneurship in insurance companies is to encourage innovation, the creation of new businesses, increase profitability while taking care to society. Corporate social responsibility means that insurance companies, following the premise of corporate entrepreneurship, in its business integrate the care of the environment in which they operate. The aim of the paper is to present the main features of social responsibility in insurance in the entrepreneurial context. In this paper we point to the definition of social responsibility in insurance, to the historical context and the importance of social responsibility as well as the latest law principles of social responsibility of insurance companies at the international level.
NOOSES OF HARMONIZATION OF DOMESTIC REGULATIONS WITH LEGAL HERITAGE OF EUROPEAN UNION (Through example of unconstitutionality of one domestic legal institute)
Authors: Blagojević Milan
Published: February 2024

In this paper the author writes on one topic which is not written about so far at us. It is word on appearance that during harmonization of domestic regulations with the law of European Union, law of the EU is very often uncritically transposed into domestic legal order. As a consequence, i.e. due to that it is not possible to realise some human rights, and in practice it leads to the violating of these rights as well. This thesis is corroborated by example from Republic of Croatia. In central part of the paper domestic legal institute of default judgement is subjected to the constitutional-legal critique in a way which points out unconstitutionality and irrationality of that institute. In the final part the author has given proposals how to remove such irregularities in a way which enables harmony in domestic legal order and it is not contrary to the legal heritage of European Union.
PARTIALITY AS A BASIS OF JUDICIAL DISQUALIFICATION AT THE INTERNATIONAL CRIMINAL TRIBUNAL FOR THE FORMER YUGOSLAVIA
Authors: Milovanović Dejan
Published: February 2024

This article analyzes principle of independence and impartiality of judges and the possibility of disqualification of judges on the basis of partiality at the International Criminal Tribunal for the former Yugoslavia, with an emphasis on practice. The article also pointed that the fair trial is a basic human right of the accused, the accused has the right to be tried by an independent and impartial court. Disqualification of a judge prevents partial and biased judges deciding in a particular case. The exclusion of judges implies the relevant, specific reasons for disqualification of judges, especially is important the required threshold of exemption. The institutional independence of the court is also important and associated with independence of individual judge. The practice of judicial exception in proceeding at the ICTY must be compared and evaluated with the stated principles and international standards of judicial independence and impartiality.
NON - ENFORCEMENT OF COURT DECISIONS ON WAR DAMAGE IN THE REPUBLIC OF SRPSKA
Authors: Kisin Jovana
Published: February 2024

Failing to enforce court decision, besides the fact that is a crime according to the Criminal Code of Republic of Srpska, primarly cause tort to a person who was awarded for damages in that decision. This article deals with the issue of final and enforceable court’s decisions against Republic of Srpska, which in spite of legal and constitutional provisions, the decisions of the Constitutional Court of the Republic of Srpska, of the Constitutional Court of Bosnia and Herzegovina and of the European Court of Human Rights, continues to postpone their execution, namely doesn’t enforce such decisions concerning the pecuniary and nonpecuniary damage incurred during the war. By this approach, the injured party who has suffered pecuniary and non-pecuniary damage during the war, also suffers damages for non-fulfillment of court’s decisions, as well as damage due to violation of basic constitutional rights guaranteed by the Constitution of Bosnia and Herzegovina and by the European Convention for the Protection of Human Rights and Fundamental Freedoms, notably the right to a fair trial and the right to property.
Research on evolution characteristics of multi-information and stability of goaf under deep tunnel
Authors: Sun Feiyue , Guo Jiaqi , Zhang Xiaobing , Li Shaohua , Liu Xiliang
Published: February 2024

In order to ensure the safety of construction and operation of the tunnel near the goaf. Based on dynamic numerical analysis, three-dimensional finite difference numerical simulation software was developed by FISH programming. Then, on basis of the construction of practical engineering, the safety distance and energy evolution mechanism in an underlying mining goaf area of deep tunnel are studied. The results show that according to the different safe distance in an underlying mining goaf area of deep tunnel, the tunnel structure is divided into danger zone, influence zone and safe zone. The relationship between the cumulative horizontal energy and stress ratio can be divided into three stages: acceleration, average stability and deceleration. The energy evolution of the three stages can also better reflect the damage and failure mechanism inside the surrounding rock mass. The measured field curve shows that when the safety distance is 12 m, the goaf has limited influence on the stability of the tunnel, and the construction in an underlying mining goaf area of deep tunnel is stable on the whole and meets the safety requirements. The best safe distance between the tunnel and goaf is about one time of the tunnel span.