bluuebunny/crossref_metadata_2025 huggingface dataset:
Cellular Ontogeny and Hierarchy Influence the Reprogramming Efficiency of Human B Cells into Induced Pluripotent Stem Cells
Authors: Muñoz-López Álvaro , van Roon Eddy. H.J. , Romero-Moya Damià , López-Millan Belén , Stam Ronald W. , Colomer Dolors , Nakanishi Mahito , Bueno Clara , Menendez Pablo
Published: February 2016

Although B cells have been shown to be refractory to reprogramming into pluripotency, induced pluripotent stem cells (iPSCs) have been very recently generated, at very low efficiency, from human cord blood (CB)- and peripheral blood (PB)-derived CD19+CD20 + B cells using nonintegrative tetracistronic OSKM-expressing Sendai Virus (SeV). Here, we addressed whether cell ontogeny and hierarchy influence the reprogramming efficiency of the B-cell compartment. We demonstrate that human fetal liver (FL)-derived CD19 + B cells are 110-fold easier to reprogram into iPSCs than those from CB/PB. Similarly, FL-derived CD34+CD19 + B progenitors are reprogrammed much easier than mature B cells (0.46% vs. 0.11%). All FL B-cell iPSCs carry complete VDJH rearrangements while 55% and 45% of the FL B-progenitor iPSCs carry incomplete and complete VDJH rearrangements, respectively, reflecting the reprogramming of developmentally different B progenitors (pro-B vs. pre-B) within a continuous differentiation process. Finally, our data suggest that successful B-cell reprogramming relies on active cell proliferation, and it is MYC-dependent as identical nonintegrative polycistronic SeV lacking MYC (OSKL or OSKLN) fail to reprogram B cells. The ability to efficiently reprogram human fetal primary B cells and B precursors offers an unprecedented opportunity for studying developmental B-lymphopoiesis and modeling B-cell malignances.
Pharmacological Regulation of In Situ Tissue Stem Cells Differentiation for Soft Tissue Calcification Treatment
Authors: Hu Jia-Jie , Yin Zi , Shen Wei-Liang , Xie Yu-Bin , Zhu Ting , Lu Ping , Cai You-Zhi , Kong Min-Jian , Heng Boon Chin , Zhou Yi-Ting , Chen Wei-Shan , Chen Xiao , Ouyang Hong-Wei
Published: February 2016

Calcification of soft tissues, such as heart valves and tendons, is a common clinical problem with limited therapeutics. Tissue specific stem/progenitor cells proliferate to repopulate injured tissues. But some of them become divergent to the direction of ossification in the local pathological microenvironment, thereby representing a cellular target for pharmacological approach. We observed that HIF-2alpha (encoded by EPAS1 inclined form) signaling is markedly activated within stem/progenitor cells recruited at calcified sites of diseased human tendons and heart valves. Proinflammatory microenvironment, rather than hypoxia, is correlated with HIF-2alpha activation and promoted osteochondrogenic differentiation of tendon stem/progenitor cells (TSPCs). Abnormal upregulation of HIF-2alpha served as a key switch to direct TSPCs differentiation into osteochondral-lineage rather than teno-lineage. Notably, Scleraxis (Scx), an essential tendon specific transcription factor, was suppressed on constitutive activation of HIF-2alpha and mediated the effect of HIF-2alpha on TSPCs fate decision. Moreover, pharmacological inhibition of HIF-2alpha with digoxin, which is a widely utilized drug, can efficiently inhibit calcification and enhance tenogenesis in vitro and in the Achilles's tendinopathy model. Taken together, these findings reveal the significant role of the tissue stem/progenitor cells fate decision and suggest that pharmacological regulation of HIF-2alpha function is a promising approach for soft tissue calcification treatment.
Rib fractures after reirradiation plus hyperthermia for recurrent breast cancer
Authors: Oldenborg Sabine , Valk Christel , van Os Rob , Oei Bing , Venselaar Jack , Vörding Paul Zum Vörde Sive , van Randen Adriënne , Crezee Hans , van Tienhoven Geertjan , Rasch Coen
Published: February 2016

Background

Combining reirradiation (reRT) and hyperthermia (HT) has shown high therapeutic value for patients with locoregional recurrent breast cancer (LR). However, additional toxicity of reirradiation (e.g., rib fractures) may occur. The aim of this study is to determine the impact of potential risk factors on the occurrence of rib fractures.

Patients and methods

From 1982–2005, 234 patients were treated with adjuvant reRT + HT after surgery for LR. ReRT consisted typically of 8 fractions of  4 Gy twice a week, or 12 fractions of  3 Gy four times a week. A total of 118 patients were irradiated with abutted photon and electron fields. In all, 60 patients were irradiated using either one or alternating combinations of abutted AP electron fields. Hyperthermia was given once or twice a week.

Results

The 5-year infield local control (LC) rate was 70 %. Rib fractures were detected in 16 of 234 patients (actuarial risk: 7 % at 5 years). All rib fractures occurred in patients treated with a combination of photon and abutted electron fields (p = 0.000); in 15 of 16 patients fractures were located in the abutment regions. The other significant predictive factors for rib fractures were a higher fraction dose (p = 0.040), large RT fields, and treatment before the year 2000.

Discussion and conclusion

ReRT + HT results in long-term LC. The majority of rib fractures were located in the photon/electron abutment area, emphasizing the disadvantage of field overlap. Large abutted photon/electron fields combined with 4 Gy fractions increase the number of rib fractures in this study group. However, as these factors were highly correlated no relative importance of the individual factors could be estimated. Increasing the number of HT sessions a week does not increase the risk of rib fractures.
Effects of Service Failure on Consumer Responses across Failure Types: A Moderating Role of Intimacy
Authors: Jeon Seongun , Kim Jonathan S.
Published: February 2016

This paper investigates a moderating role of intimacy in two service failure types (outcome and process failure), considering two consumer responses: buffering and betrayal effect. Study 1 employs a 3 (failure type: no vs. outcome vs. process) × 2 (intimacy level: high vs. low) experimental design. Findings show that in case involving outcome failure, a high intimacy group has higher service evaluations (satisfaction, re-patronage intention, and positive word-of-mouth intention) than a low intimacy group, substantiating the existence of buffering effect. In case involving process failure, however, service evaluations are not different depending on the level of intimacy, invalidating the existence of betrayal effect. Study 2 analyzes the effects of intimacy (high vs. low) on service evaluations in the setting of process failure and following failed recovery. The results reveal that betrayal effect is indeed present in times of double deviation, process failure and following failed recovery. Consequently, this research offers service providers practical insights on how to utilize intimacy based on the classification of service failure types.
Prevalence of repeat pregnancies and associated factors among teenagers in KwaZulu‐Natal, South Africa
Authors: Mphatswe Wendy , Maise Hopolang , Sebitloane Motshedisi
Published: February 2016

Objective

To determine the prevalence of repeat teenage pregnancy and the interval between first/most recent and repeat pregnancies, as well as to evaluate the sexual/reproductive health characteristics of teenagers with repeat pregnancies.

Methods

A prospective observational study was undertaken at a hospital in KwaZulu‐Natal, South Africa, between May and September 2013. Teenagers aged 13–19 years who were pregnant, had recently delivered, or had terminated a pregnancy were enrolled. A questionnaire was used to obtain data.

Results

Among 341 participants, 281 (82.4%) were seen for a first pregnancy and 60 (17.6%) for a repeat pregnancy. The interval between first/most recent and repeat pregnancies was 24 months or lower in 45 (75.0%) of repeat pregnancy participants. Only 58 (17.0%) participants had previously used contraception (54 [93.1%] of whom stopped within 12 months) and 28 (8.2%) had used emergency contraception. More participants with repeat pregnancy than with first pregnancy had a positive HIV status (18 [30.0%] vs 26 [9.3%]; P < 0.001), more than one sexual partner in the past 12 months (21 [35.0%] vs 35 [12.5%]; P < 0.001), and a partner at least 5 years older (38 [63.3%] vs 128 [45.6%]; P < 0.001).

Conclusion

High repeat pregnancy rates, low contraception use, and high HIV prevalence among teenagers in South Africa is worrying. Focused interventions targeting teenagers following their first pregnancy need to be urgently implemented.
Magma sources in the mantle wedge beneath the volcanoes of the Klyuchevskoy group and Kizimen based on seismic tomography modeling
Authors: Koulakov I.Yu. , Kukarina E.V. , Gordeev E.I. , Chebrov V.N. , Vernikovsky V.A.
Published: February 2016

This study presents a 3D model of the P and S seismic velocities above the Kamchatkan slab obtained as a result of tomographic inversion of arrival times of body waves from deep seismicity in the subduction zone. Various tests performed have shown limitations of the spatial resolution of the model and provided arguments for the reliability of the major structures used in the interpretation. In the uppermost layer down to 20 km depth, the model reveals strong low-velocity anomalies coinciding with Holocene volcanoes of the Klyuchevskoy group and Kizimen. In the seismogenic zone at depths from 80 to 150 km, we observe a low-velocity anomaly, which probably reflects the presence of the relatively thick oceanic crust sinking together with the subducting slab. This anomaly may also represent a zone of phase transitions, melting, and release of fluids from the slab. In the cross sections, we observe vertical and inclined low-velocity anomalies connecting the slab with the volcanic groups that probably represent the paths of ascending fluids and melts, which feed the volcanoes. In the case of Kizimen, we observe a single conduit connecting the volcano with the slab transformation area at 100 km depth. Beneath the Klyuchevskoy group, we identify several linear inclined patterns having different dipping angles. This may show that the volcanoes of the group are fed from different segments of the slab and might be one of the reasons for the diversity of lava compositions in the volcanoes of the Klyuchevskoy group.
The WTO and International Investment Law
Authors: Kurtz Jürgen
Published: February 2016

International law has historically regulated foreign trade and foreign investment differently. Distinct evolutionary pathways have led to variances in treaty form, institutional culture, and dispute settlement. With their inevitable erosion through the late twentieth to early twenty-first centuries, those weak boundaries have become porous and indefensible. Powerful economic, legal and sociological factors are now pushing the two systems together. In this book, Jürgen Kurtz systematically explores the often complex and little-understood dynamics of this convergence phenomenon. Kurtz addresses the growing connections between international trade and investment law, proposing a theoretically grounded and doctrinally tractable framework to understand the deepening relationship between them. The book also offers reform ideas and possibilities, providing treaty negotiators and other government officials with a set of theoretical insights and doctrinal models that can guide actors in building a justifiable and sustainable level of commonality between the two legal systems.
The Governance of the Countryside
Authors: Hodge Ian
Published: February 2016

Conflicts over the conservation of biodiversity, changing patterns in land use, pollution, climate change, public access and increasing demands for food and energy security lead to the creation of policies designed to reconcile interests and promote society's objectives. This book examines the origins and evolution of the institutions that determine the use and management of land and the delivery of ecosystem services, through private property rights, markets and public policies. Divided into five accessible parts, the book provides detailed coverage of the institutions, property and governance of the countryside, historical models, governance under sectoral policies and alternative approaches. It is carefully developed to meet the needs of anyone studying or interested in agricultural sciences, countryside management, rural environment and geography. Students, lecturers, policy makers, managers and consultants in these areas will find this a valuable resource.
Handel on the Stage
Authors: Kimbell David
Published: February 2016

Of all the great composers of the eighteenth century, Handel was the supreme cosmopolitan, an early and extraordinarily successful example of a freelance composer. For thirty years the opera-house was the principal focus of his creative work and he composed more than forty operas over this period. In this book, David Kimbell sets Handel's operas in their biographical and cultural contexts. He explores the circumstances in which they were composed and performed, the librettos that were prepared for Handel, and what they tell us about his and his audience's values and the music he composed for them. Remarkably no Handel operas were staged for a period of 170 years between 1754 and the 1920s. The final chapter in this book reveals the differences and similarities between how Handel's operas were performed in his time and ours.
Long-Vowel Shifts in English, c. 1050–1700
Authors: Stenbrenden Gjertrud Flermoen
Published: February 2016

The English language has undergone many sound changes in its long history. Some of these changes had a profound effect on the pronunciation of the language. A number of these significant instances of language evolution are generally grouped together and termed the 'Great Vowel Shift'. These changes are generally considered to be unrelated to other, similar long-vowel changes taking place a little earlier. This book assesses an extensive range of irregular Middle English spellings for all these changes, with a view to identifying the real course of events: the dates, the chronology, and the dialects that stand out as being innovative. Using empirical evidence to offer a fresh perspective and drawing new, convincing conclusions, Stenbrenden offers an interpretation of the history of the English language which may change our view of sound change completely.
Citizenship, Alienage, and the Modern Constitutional State
Authors: Irving Helen
Published: February 2016

To have a nationality is a human right. But between the nineteenth and mid-twentieth centuries, virtually every country in the world adopted laws that stripped citizenship from women who married foreign men. Despite the resulting hardships and even statelessness experienced by married women, it took until 1957 for the international community to condemn the practice, with the adoption of the United Nations Convention on the Nationality of Married Women. Citizenship, Alienage, and the Modern Constitutional State tells the important yet neglected story of marital denaturalization from a comparative perspective. Examining denaturalization laws and their impact on women around the world, with a focus on Australia, Britain, Canada, Ireland, New Zealand and the United States, it advances a concept of citizenship as profoundly personal and existential. In doing so, it sheds light on both a specific chapter of legal history and the theory of citizenship in general.
Across Forest, Steppe, and Mountain
Authors: Bello David A.
Published: February 2016

In this book, David Bello offers a new and radical interpretation of how China's last dynasty, the Qing (1644–1911), relied on the interrelationship between ecology and ethnicity to incorporate the country's far-flung borderlands into the dynasty's expanding empire. The dynasty tried to manage the sustainable survival and compatibility of discrete borderland ethnic regimes in Manchuria, Inner Mongolia, and Yunnan within a corporatist 'Han Chinese' imperial political order. This unprecedented imperial unification resulted in the great human and ecological diversity that exists today. Using natural science literature in conjunction with under-utilized and new sources in the Manchu language, Bello demonstrates how Qing expansion and consolidation of empire was dependent on a precise and intense manipulation of regional environmental relationships.
Dynamics
Authors: Roithmayr Carlos M. , Hodges Dewey H.
Published: February 2016

This book is ideal for teaching students in engineering or physics the skills necessary to analyze motions of complex mechanical systems such as spacecraft, robotic manipulators, and articulated scientific instruments. Kane's method, which emerged recently, reduces the labor needed to derive equations of motion and leads to equations that are simpler and more readily solved by computer, in comparison to earlier, classical approaches. Moreover, the method is highly systematic and thus easy to teach. This book is a revision of Dynamics: Theory and Applications by T. R. Kane and D. A. Levinson and presents the method for forming equations of motion by constructing generalized active forces and generalized inertia forces. Important additional topics include approaches for dealing with finite rotation, an updated treatment of constraint forces and constraint torques, an extension of Kane's method to deal with a broader class of nonholonomic constraint equations, and other recent advances.
Dynamics of Quantised Vortices in Superfluids
Authors: Sonin Edouard B.
Published: February 2016

A comprehensive overview of the basic principles of vortex dynamics in superfluids, this book addresses the problems of vortex dynamics in all three superfluids available in laboratories (4He, 3He, and BEC of cold atoms) alongside discussions of the elasticity of vortices, forces on vortices, and vortex mass. Beginning with a summary of classical hydrodynamics, the book guides the reader through examinations of vortex dynamics from large scales to the microscopic scale. Topics such as vortex arrays in rotating superfluids, bound states in vortex cores and interaction of vortices with quasiparticles are discussed. The final chapter of the book considers implications of vortex dynamics to superfluid turbulence using simple scaling and symmetry arguments. Written from a unified point of view that avoids complicated mathematical approaches, this text is ideal for students and researchers working with vortex dynamics in superfluids, superconductors, magnetically ordered materials, neutron stars and cosmological models.
Ethics and Health Care
Authors: Moskop John C.
Published: February 2016

Who should have access to assisted reproductive technologies? Which one of many seriously ill patients should be offered the next available transplant organ? When may a surrogate decision maker decide to withdraw life-prolonging measures from an unconscious patient? Questions like these feature prominently in the field of health care ethics and in the education of health care professionals. This book provides a concise introduction to the major concepts, principles and issues in health care ethics, using case studies throughout to illustrate and analyse challenging ethical issues in contemporary health care. Topics range widely, from confidentiality and truthfulness to end-of-life care and research on human subjects. Ethics and Health Care will be a vital resource for students of applied ethics, bioethics, professional ethics, health law and medical sociology, as well as students of medicine, nursing and other health care professions.
Ancient and Modern Democracy
Authors: Nippel Wilfried
Published: February 2016

Ancient and Modern Democracy is a comprehensive account of Athenian democracy as a subject of criticism, admiration and scholarly debate for 2,500 years, covering the features of Athenian democracy, its importance for the English, American and French revolutions and for the debates on democracy and political liberty from the nineteenth century to the present. Discussions were always in the context of contemporary constitutional problems. Time and again they made a connection with a long-established tradition, involving both dialogue with ancient sources and with earlier phases of the reception of Antiquity. They refer either to a common cultural legacy or to specific national traditions; they often involve a mixture of political and scholarly arguments. This book elucidates the complexity of considering and constructing systems of popular self-rule.
International Copyright and Access to Knowledge
Authors: Bannerman Sara
Published: February 2016

The principle of Access to Knowledge (A2K) has become a common reference point for a diverse set of agendas that all hope to realize technological and human potential by making knowledge more accessible. This book is a history of international copyright focused on principles of A2K and their proponents. Whilst debate and discussion so far has covered the perspectives of major western countries, the author's fresh approach to the topic considers emerging countries and NGOs, who have fought for the principles of A2K that are now fundamental to the system. Written in a clear and accessible style, the book connects copyright history to current problems, issues and events.
Cicero, De Finibus Bonorum et Malorum
Authors: Madvig Johan Nicolai , Cicero Marcus Tullius
Published: February 2016

Published in Copenhagen in 1879, this Cambridge edition is the third edition of Cicero's De Finibus by Johan Nicolai Madvig (1804–1886), first published in 1839. A Danish politician and leading classical scholar at the University of Copenhagen, Madvig was critical of what he considered careless German scholarship, and he sought a return to a truer manuscript tradition. His work focussed on Cicero and culminated in the first edition of De Finibus, which defined the standard for sound textual criticism. De Finibus Bonorum et Malorum (On the Ends of Good and Evil) is the most extensive of Cicero's works, in which he criticises three ancient philosophical schools of thought: Epicureanism, Stoicism, and the Platonism of the Academy of Antiochus. This third edition contains a revised preface outlining Madvig's method of ranking texts, and the five books of De Finibus.
The History, Antiquities, Topography, and Statistics of Eastern India
Authors: Martin Robert Montgomery
Published: February 2016

In 1807, the Directors of the East India Company ordered a survey of the nine districts, covering 60,000 square miles and containing 15,000,000 British subjects, which formed the Eastern territories of British India. In this three-volume work, published in 1838, Irish civil servant and author Robert Montgomery Martin (1801–68) compiled and collated the original survey material at East India House to describe the geography, geology, meteorology, natural history, agriculture and manufactures, population, history, architecture, fine arts, religion and education of this huge area. Martin, the first colonial Treasurer of Hong Kong, founder of the East India Association, author of History of the British Colonies (1834–5), and later publisher of the Duke of Wellington's dispatches, carried out his work to alert the British public to the growing social and political problems he perceived in India. Volume 1 covers the districts of Behar (Patna City) and Shahabad.
Pragmatic Markers in British English
Authors: Beeching Kate
Published: February 2016

Fundamental to oral fluency, pragmatic markers facilitate the flow of spontaneous, interactional and social conversation. Variously termed 'hedges', 'fumbles' and 'conversational greasers' in earlier academic studies, this book explores the meaning, function and role of 'well', 'I mean', 'just', 'sort of', 'like' and 'you know' in British English. Adopting a sociolinguistic and historical perspective, Beeching investigates how these six commonly occurring pragmatic markers are used and the ways in which their current meanings and functions have evolved. Informed by empirical data from a wide range of contemporary and historical sources, including a small corpus of spoken English collected in 2011–14, the British National Corpus and the Old Bailey Corpus, Pragmatic Markers in British English contributes to debates about language variation and change, incrementation in adolescence and grammaticalisation and pragmaticalisation. It will be fascinating reading for researchers and students in linguistics and English, as well as non-specialists intrigued by this speech phenomenon.
Statistical Methods for Recommender Systems
Authors: Agarwal Deepak K. , Chen Bee-Chung
Published: February 2016

Designing algorithms to recommend items such as news articles and movies to users is a challenging task in numerous web applications. The crux of the problem is to rank items based on users' responses to different items to optimize for multiple objectives. Major technical challenges are high dimensional prediction with sparse data and constructing high dimensional sequential designs to collect data for user modeling and system design. This comprehensive treatment of the statistical issues that arise in recommender systems includes detailed, in-depth discussions of current state-of-the-art methods such as adaptive sequential designs (multi-armed bandit methods), bilinear random-effects models (matrix factorization) and scalable model fitting using modern computing paradigms like MapReduce. The authors draw upon their vast experience working with such large-scale systems at Yahoo! and LinkedIn, and bridge the gap between theory and practice by illustrating complex concepts with examples from applications they are directly involved with.
The Cambridge Introduction to Performance Theory
Authors: Shepherd Simon
Published: February 2016

What does 'performance theory' really mean and why has it become so important across such a large number of disciplines, from art history to religious studies and architecture to geography? In this introduction Simon Shepherd explains the origins of performance theory, defines the terms and practices within the field and provides new insights into performance's wide range of definitions and uses. Offering an overview of the key figures, their theories and their impact, Shepherd provides a fresh approach to figures including Erving Goffman and Richard Schechner and ideas such as radical art practice, performance studies, radical scenarism and performativity. Essential reading for students, scholars and enthusiasts, this engaging account travels from universities into the streets and back again to examine performance in the context of political activists and teachers, countercultural experiments and feminist challenges, and ceremonies and demonstrations.
Trade, Investment, Innovation and their Impact on Access to Medicines
Authors: Hsu Locknie
Published: February 2016

The last two decades have seen great economic change in Asia and this has impacted upon the vexed question of access to affordable healthcare and medicines in many Asian states. In this book Locknie Hsu examines the issue of access to medicines in Asia from a fresh perspective which embraces trade and investment law, innovation, intellectual property law, competition policy and public health issues. Hsu explores the key evolving legal issues in these areas, including ASEAN integration, free trade agreement negotiations (such as those for the TPP), bilateral investment agreements and significant court decisions. The book goes on to present proposals for steps to be taken in addressing access to medicines in Asia and will be useful to academic researchers, regulators, law-makers and global organizations involved in the issues surrounding access to affordable healthcare and medicines.
New Histories of the Andaman Islands
Authors: Anderson Clare , Mazumdar Madhumita , Pandya Vishvajit
Published: February 2016

This innovative, multidisciplinary exploration of the unique history of the Andaman Islands as a hunter-gatherer society, colonial penal colony, and state-engineered space of settlement and development ranges across the theoretical, conceptual and thematic concerns of history, anthropology and historical geography. Covering the entire period of post-settlement Andamans history, from the first (failed) British occupation of the Islands in the 1790s up to the year 2012, the authors examine imperial histories of expansion and colonization, decolonization, anti-colonialism and nationalism, Japanese occupation, independence and partition, migration, commemoration and contemporary issues of Indigenous welfare. New Histories of the Andaman Islands offers a new way of thinking about the history of South Asia, and will be thought-provoking reading for scholars of settler colonial societies in other contexts, as well as those engaged in studies of nationalism and postcolonial state formation, ecology, visual cultures and the politics of representation.
Thinking about Human Memory
Authors: Humphreys Michael S. , Chalmers Kerry A.
Published: February 2016

Thinking About Human Memory provides a novel analytical approach to understanding memory that considers the goals of the memory task, the cues and information available, the opportunity to learn, and interference from irrelevant information (noise). Each of the five chapters describing this approach introduces historical ideas and demonstrates how current thinking both differs from and is derived from them. These chapters also contain analyses of current problems designed to demonstrate the power of the approach. In a subsequent chapter, the authors discuss how memory is controlled by the environment, by others, and by ourselves, and then apply their insights to the problem solving of children, our hominin ancestors, and scrub jays. Finally, the questions of how to define episodic memory and how to investigate phylogenetic and developmental changes in memory are addressed. This book will appeal to memory researchers, including applied researchers, and advanced students.
From the Knowledge Argument to Mental Substance
Authors: Robinson Howard
Published: February 2016

This book presents a strong case for substance dualism and offers a comprehensive defense of the knowledge argument, showing that materialism cannot accommodate or explain the 'hard problem' of consciousness. Bringing together the discussion of reductionism and semantic vagueness in an original and illuminating way, Howard Robinson argues that non-fundamental levels of ontology are best treated by a conceptualist account, rather than a realist one. In addition to discussing the standard versions of physicalism, he examines physicalist theories such as those of McDowell and Price, and accounts of neutral monism and panpsychism from Strawson, McGinn and Stoljar. He also explores previously unnoticed historical parallels between Frege and Aristotle and between Hume and Plotinus. His book will be a valuable resource for scholars and advanced students of philosophy of mind, in particular those looking at consciousness, dualism, and the mind-body problem.
Jewish Radical Ultra-Orthodoxy Confronts Modernity, Zionism and Women's Equality
Authors: Inbari Motti
Published: February 2016

In Jewish Radical Ultra-Orthodoxy Confronts Modernity, Zionism and Women's Equality, Motti Inbari undertakes a study of the culture and leadership of Jewish radical ultra-Orthodoxy in Hungary, Jerusalem and New York. He reviews the history, ideology and gender relations of prominent ultra-Orthodox leaders Amram Blau (1894–1974), founder of the anti-Zionist Jerusalemite Neturei Karta, and Yoel Teitelbaum (1887–1979), head of the Satmar Hasidic movement in New York. Focussing on the rabbis' biographies, the author analyzes their enclave building methods, their attitude to women and modesty, and their eschatological perspectives. The research is based on newly discovered archival materials, covering many unique and remarkable findings. The author concludes with a discussion of contemporary trends in Jewish religious radicalization. Inbari highlights the resilience of the current generations' sense of community cohesion and their capacity to adapt and overcome challenges such as rehabilitation into potentially hostile secular societies.
Continuum Mechanics and Thermodynamics of Matter
Authors: Paolucci S.
Published: February 2016

Aimed at advanced undergraduate and graduate students, this book provides a clear unified view of continuum mechanics that will be a welcome addition to the literature. Samuel Paolucci provides a well-grounded mathematical structure and also gives the reader a glimpse of how this material can be extended in a variety of directions, furnishing young researchers with the necessary tools to venture into brand new territory. Particular emphasis is given to the roles that thermodynamics and symmetries play in the development of constitutive equations for different materials. Continuum Mechanics and Thermodynamics of Matter is ideal for a one-semester course in continuum mechanics, with 250 end-of-chapter exercises designed to test and develop the reader's understanding of the concepts covered. Six appendices enhance the material further, including a comprehensive discussion of the kinematics, dynamics and balance laws applicable in Riemann spaces.
Optimization in Chemical Engineering
Authors: Dutta Suman
Published: February 2016

Optimization is used to determine the most appropriate value of variables under given conditions. The primary focus of using optimisation techniques is to measure the maximum or minimum value of a function depending on the circumstances. This book discusses problem formulation and problem solving with the help of algorithms such as secant method, quasi-Newton method, linear programming and dynamic programming. It also explains important chemical processes such as fluid flow systems, heat exchangers, chemical reactors and distillation systems using solved examples. The book begins by explaining the fundamental concepts followed by an elucidation of various modern techniques including trust-region methods, Levenberg–Marquardt algorithms, stochastic optimization, simulated annealing and statistical optimization. It studies the multi-objective optimization technique and its applications in chemical engineering and also discusses the theory and applications of various optimization software tools including LINGO, MATLAB, MINITAB and GAMS.
Fracture Mechanics
Authors: Maiti Surjya Kumar
Published: February 2016

Fracture mechanics studies the development and spreading of cracks in materials. The study uses two techniques including analytical and experimental solid mechanics. The former is used to determine the driving force on a crack and the latter is used to measure material's resistance to fracture. The text begins with a detailed discussion of fundamental concepts including linear elastic fracture mechanics (LEFM), yielding fracture mechanics, mixed mode fracture and computational aspects of linear elastic fracture mechanics. It explains important topics including Griffith theory of brittle crack propagation and its Irwin and Orowan modification, calculation of theoretical cohesive strength of materials through an atomic model and analytical determination of crack tip stress field. This book covers MATLAB programs for calculating fatigue life under variable amplitude cyclic loading. The experimental measurements of fracture toughness parameters KIC, JIC and crack opening displacement (COD) are provided in the last chapter.
Fundamentals of Sum-Frequency Spectroscopy
Authors: Shen Y. R.
Published: February 2016

The first book on the topic, and written by the founder of the technique, this comprehensive resource provides a detailed overview of sum-frequency spectroscopy, its fundamental principles, and the wide range of applications for surfaces, interfaces, and bulk. Beginning with an overview of the historical context, and introductions to the basic theory of nonlinear optics and surface sum-frequency generation, topics covered include discussion of different experimental arrangements adopted by researchers, notes on proper data analysis, an up-to-date survey commenting on the wide range of successful applications of the tool, and a valuable insight into current unsolved problems and potential areas to be explored in the future. With the addition of chapter appendices that offer the opportunity for more in-depth theoretical discussion, this is an essential resource that integrates all aspects of the subject and is ideal for anyone using, or interested in using, sum-frequency spectroscopy.
The Future of Financial Regulation
Authors: Lybeck Johan A.
Published: February 2016

A number of changes have been made to the supervision and regulation of banks as a result of the recent financial meltdown. Some are for the better, such as the Basel III rules for increasing the quality and quantity of capital in banks, but legal changes on both sides of the Atlantic now make it much more difficult to resolve failing banks by means of taxpayer funded bail-outs and could hinder bank resolution in future financial crises. In this book, Johan A. Lybeck uses case studies from Europe and the United States to examine and grade a number of bank resolutions in the last financial crisis and establish which were successful, which failed, and why. Using in-depth analysis of recent legislation, he explains how a bank resolution can be successful, and emphasizes the need for taxpayer-funded bail-outs to create a viable banking system that will promote economic and financial stability.
Radio and the Politics of Sound in Interwar France, 1921–1939
Authors: Scales Rebecca P.
Published: February 2016

In December 1921, France broadcast its first public radio program from a transmitter on the Eiffel Tower. In the decade that followed, radio evolved into a mass media capable of reaching millions. Crowds flocked to loudspeakers on city streets to listen to propaganda, children clustered around classroom radios, and families tuned in from their living rooms. Radio and the Politics of Sound in Interwar France, 1921–1939 examines the impact of this auditory culture on French society and politics, revealing how broadcasting became a new platform for political engagement, transforming the act of listening into an important, if highly contested, practice of citizenship. Rejecting models of broadcasting as the weapon of totalitarian regimes or a tool for forging democracy from above, the book offers a more nuanced picture of the politics of radio by uncovering competing interpretations of listening and diverse uses of broadcast sound that flourished between the world wars.
Confounding Powers
Authors: Brenner William J.
Published: February 2016

Nearly a decade and a half after 9/11, the study of international politics has yet to address some of the most pressing issues raised by the attacks, most notably the relationships between Al Qaeda's international systemic origins and its international societal effects. This theoretically broad-ranging and empirically far-reaching study addresses that question and others, advancing the study of international politics into new historical settings while providing insights into pressing policy challenges. Looking at actors that depart from established structural and behavioral patterns provides opportunities to examine how those deviations help generate the norms and identities that constitute international society. Systematic examination of the Assassins, Mongols, and Barbary powers provides historical comparison and context to our contemporary struggle, while enriching and deepening our understanding of the systemic forces behind, and societal effects of, these confounding powers.
Luther's Legacy
Authors: von Friedeburg Robert
Published: February 2016

In this new account of the emergence of a distinctive territorial state in early modern Germany, Robert von Friedeburg examines how the modern notion of state does not rest on the experience of a bureaucratic state-apparatus. It emerged to stabilize monarchy from dynastic insecurity and constrain it to protect the rule of law, subjects, and their lives and property. Against this background, Lutheran and neo-Aristotelian notions on the spiritual and material welfare of subjects dominating German debate interacted with Western European arguments against 'despotism' to protect the lives and property of subjects. The combined result of this interaction under the impact of the Thirty Years War was Seckendorff's Der Deutsche Fürstenstaat (1656), constraining the evil machinations of princes and organizing the detailed administration of life in the tradition of German Policey, and which founded a specifically German notion of the modern state as comprehensive provision of services to its subjects.
The Making of International Human Rights
Authors: Jensen Steven L. B.
Published: February 2016

This book fundamentally reinterprets the history of international human rights in the post-1945 era by documenting how pivotal the Global South was for their breakthrough. In stark contrast to other contemporary human rights historians who have focused almost exclusively on the 1940s and the 1970s - heavily privileging Western agency - Steven L. B. Jensen convincingly argues that it was in the 1960s that universal human rights had their breakthrough. This is a ground-breaking work that places race and religion at the center of these developments and focuses on a core group of states who led the human rights breakthrough, namely Jamaica, Liberia, Ghana, and the Philippines. They transformed the norms upon which the international community today is built. Their efforts in the 1960s post-colonial moment laid the foundation - in profound and surprising ways - for the so-called human rights revolution in the 1970s, when Western activists and states began to embrace human rights.
Beauty and Sublimity
Authors: Hogan Patrick Colm
Published: February 2016

Recent decades have witnessed an explosion in neuroscientific and related research treating aesthetic response. This book integrates this research with insights from philosophical aesthetics to propose new answers to longstanding questions about beauty and sublimity. Hogan begins by distinguishing what we respond to as beautiful from what we count socially as beautiful. He goes on to examine the former in terms of information processing (specifically, prototype approximation and non-habitual pattern recognition) and emotional involvement (especially of the endogenous reward and attachment systems). In the course of the book, Hogan examines such issues as how universal principles of aesthetic response may be reconciled with individual idiosyncrasy, how it is possible to argue rationally over aesthetic response, and what role personal beauty and sublimity might play in the definition of art. To treat these issues, the book considers works by Woolf, Wharton, Shakespeare, Arthur Miller, Beethoven, Matisse, and Kiran Rao, among others.
Toxic Histories
Authors: Arnold David
Published: February 2016

Toxic Histories combines social, scientific, medical and environmental history to demonstrate the critical importance of poison and pollution to colonial governance, scientific authority and public anxiety in India between the 1830s and 1950s. Against the background of India's 'poison culture' and periodic 'poison panics', David Arnold considers why many familiar substances came to be regarded under colonialism as dangerous poisons. As well as the criminal uses of poison, Toxic Histories shows how European and Indian scientists were instrumental in creating a distinctive system of forensic toxicology and medical jurisprudence designed for Indian needs and conditions, and how local, as well as universal, poison knowledge could serve constructive scientific and medical purposes. Arnold reflects on how the 'fear of a poisoned world' spilt over into concerns about contamination and pollution, giving ideas of toxicity a wider social and political significance that has continued into India's postcolonial era.
Organized Violence after Civil War
Authors: Daly Sarah Zukerman
Published: February 2016

Nearly half of all countries emerging from civil conflict relapse into war within a few years of signing a peace agreement. The postwar trajectories of armed groups vary from organizational cohesion to dissolution, demilitarization to remilitarization. In Organized Violence after Civil War, Daly analyzes evidence from thirty-seven militia groups in Colombia, demonstrating that the primary driving force behind these changes is the variation in recruitment patterns within, and between, the warring groups. She documents the transition from war to peace through interviews with militia commanders, combatants and victims. Using rich ex-combatant survey data and geo-coded information on violence over fifty years of war, Daly explains the dynamics inside armed organizations and the strategic interactions among them. She also shows how the theory may be used beyond Colombia, both within the region of Latin America and across the rest of the world.
Probability on Real Lie Algebras
Authors: Franz Uwe , Privault Nicolas
Published: February 2016

This monograph is a progressive introduction to non-commutativity in probability theory, summarizing and synthesizing recent results about classical and quantum stochastic processes on Lie algebras. In the early chapters, focus is placed on concrete examples of the links between algebraic relations and the moments of probability distributions. The subsequent chapters are more advanced and deal with Wigner densities for non-commutative couples of random variables, non-commutative stochastic processes with independent increments (quantum Lévy processes), and the quantum Malliavin calculus. This book will appeal to advanced undergraduate and graduate students interested in the relations between algebra, probability, and quantum theory. It also addresses a more advanced audience by covering other topics related to non-commutativity in stochastic calculus, Lévy processes, and the Malliavin calculus.
Foundations of Ergodic Theory
Authors: Viana Marcelo , Oliveira Krerley
Published: February 2016

Rich with examples and applications, this textbook provides a coherent and self-contained introduction to ergodic theory, suitable for a variety of one- or two-semester courses. The authors' clear and fluent exposition helps the reader to grasp quickly the most important ideas of the theory, and their use of concrete examples illustrates these ideas and puts the results into perspective. The book requires few prerequisites, with background material supplied in the appendix. The first four chapters cover elementary material suitable for undergraduate students – invariance, recurrence and ergodicity – as well as some of the main examples. The authors then gradually build up to more sophisticated topics, including correlations, equivalent systems, entropy, the variational principle and thermodynamical formalism. The 400 exercises increase in difficulty through the text and test the reader's understanding of the whole theory. Hints and solutions are provided at the end of the book.
China's Troubled Waters
Authors: Chan Steve
Published: February 2016

How are China's ongoing sovereignty disputes in the East and South China Seas likely to evolve? Are relations across the Taiwan Strait poised to enter a new period of relaxation or tension? How are economic interdependence, domestic public opinion, and the deterrence role played by the US likely to affect China's relations with its counterparts in these disputes? Although territorial disputes have been the leading cause for interstate wars in the past, China has settled most of its land borders with its neighbours. Its maritime boundaries, however, have remained contentious. This book examines China's conduct in these maritime disputes in order to analyse Beijing's foreign policy intentions in general. Rather than studying Chinese motives in isolation, Steve Chan uses recent theoretical and empirical insights from international relations research to analyse China's management of its maritime disputes.