bluuebunny/crossref_metadata_2025 huggingface dataset:
What do Children Want? A Conceptualisation of Evolutionary Influences on Children's Motivation in the Peer Group
Authors: MacDonald Kevin
Published: March 2013

This paper presents an evolutionary perspective on children's resourcedirected behaviour in peer groups. It is argued that reciprocity is theoretically expected to be the fundamental rule of resource exchange in peer relationships of friendship. Children are therefore expected to be attracted to peers who are similar to themselves on a wide variety of traits. These traits are viewed as resources in peer relationships, and individual differences in these traits represent a resource environment for children. In this paper, the resource environment represented by individual differences in several evolved motivational systems will be emphasised. The discussion focuses on such three evolved systems, the sensation seeking/impulsivity system, the human affectional system, and the behavioural inhibition system. It is concluded that individual differences in these systems are important for understanding friendship and sociometric status in children's peer relationships.
Japanese Childrearing Advice in its Cultural, Social, and Economic Contexts
Authors: Kojima Hideo
Published: March 2013

After describing the background and current state of historical interests among Japanese developmentalists, this article stresses the value of the direct participation of developmentalists in historical study. Japanese historical materials on childrearing were analysed from a developmental point of view and their relation to cultural, social, and economic contexts in five historical epochs was examined. The results revealed historical continuity of basic beliefs and values in Japanese ethnotheories on childrearing and human development, and their relation to certain structural and functional aspects of Japanese society was demonstrated. A new term, the "ethnopsychological pool of ideas" (EPI), is presented to denote a reservoir of knowledge, practices, sentiments, and values that maintains diverse components across historical periods. The ethnopsychological pool of early modem Japan contained divergent key components based on which a few schools of modem academic theories on child development can be constructed. The analysis suggests that theories of childrearing draw upon naive psychology, expert advice, and scientific psychology, and are mutually related as social constructions based on the ethnopsychological pool of ideas of a particular society.
Intergenerational Continuity and Change in Rural Lives: Historical and Developmental Insights
Authors: Elder Glen H. , King Valarie , Conger Rand D.
Published: March 2013

Sudden forms of drastic social change have attracted the attention of developmentalists in recent years through their compelling human consequences. Examples include economic depressions, wars, and political transformations. This study focuses on a less visible but no less profound social change and its developmental implications for children, the declining rural population. Using a sample of Iowa fathers (USA) who grew up on farms, we compared the family experience and children of men who followed either the path of farming or of nonfarm employment. Farm children experience greater social inter-dependency with other family members, and this reinforces their feeling of social significance-they mattered for others and also shared responsibility for others. As might be expected, farm youth acquired stronger attachments to their local community and family which were expressed in subsequent agricultural activities and goals. The antecedents and correlates of rural preferences begin to tell the story of rural farm continuity and change in the next generation.
Shyness Ratings: Stability and Correlates in Early Childhood
Authors: Sanson A. , Pedlow R. , Cann W. , Prior M. , Oberklaid F.
Published: March 2013

This study explores the stability and correlates of shyness from infancy to 6 years of age using five sets of data from a large representative sample. Included in each set are maternal ratings on a temperament dimension named Approach which assesses reactions to new people and situations, and is the measure of shyness employed here. Two issues are examined: (1) the stability of shyness as revealed by log-linear analyses, in comparison to other temperamental attributes, and when comparing extreme groups to those with moderate scores; (2) the correlates of shyness in infancy and at 5-6 years. The results suggest that the stability of shyness from 1-2 years onwards is moderate, and similar in level and patterning to other temperamental attributes. Comparisons of four subgroups differing on shyness indicate differences on other temperamental and behavioural characteristics; shyness was related to general "difficultness" in infancy, but at 5-6 years was associated with the presence of internalising problems and the absence of externalising problems.
The Effects of Expertise and IQ on Children's Memory: When Knowledge is, and When it is Not Enough
Authors: Schneider Wolfgang , Bjorklund David F. , Maier-Bruckner Wolfgang
Published: March 2013

Two experiments were conducted to investigate the assumption that rich domain knowledge can compensate for low overall aptitude on domain-related cognitive tasks. Whereas previous research dealing with text recall and text comprehension tasks has provided evidence supporting this assumption, recent studies examining the effects of both expertise and intelligence on a strategic memory task (sort-recall task) found that the effects of domain knowledge were not strong enough to eliminate performance differences between high-and low-aptitude experts. In our experiments, both text-recall and sort-recall measures related to the game of soccer were presented to high-and low-aptitude fourth-grade children who were either soccer experts or novices, using a within-subjects design. The main difference between the two studies concerned the testing procedure: Whereas in Study 1 testing was conducted in small groups, in Study 2 children were tested individually. Both studies confirmed the outcome of previous research; that is, effects of aptitude on text recall and comprehension were eliminated when the impact of expertise was considered simultaneously. However, they also replicated the earlier finding that this pattern of results does not generalise to other memory tasks. That is, expertise does reduce but not eliminate the relationship of IQ to memory tasks involving deliberate strategies.
Oral History And Dalit Testimonies: From The Ordeal To Speak To The Necessity To Testify
Authors: Heering Alexandra de
Published: March 2013

The development of dalit literature and history plays a vital part in the effort of dalit communities to (re)gain recognition in Indian society. Victims of multiform discrimination in the name of caste, dalits have used these areas of self-knowledge to assert themselves culturally and socially. Indian society and mainstream intellectuals continue, however, to deny the value and legitimacy of dalit historical and literary productions. There is a tendency to believe that dalits should be kept out of the mainstream and effectively silenced. Therefore, testifying through writings or oral narratives still requires courage and determination. It certainly seems to be a demanding ordeal for those paving the way for dalit expression. This article, based on oral history fieldwork conducted among dalit (Cakkiliyar) communities in Tamil Nadu, as well as on written testimonies, highlights factors preventing dalits from exercising freedom of speech and also discusses some reasons why dalits do decide to speak.
Necrotizing Meningoencephalitis in a Cow
Authors: Rissi D. R. , Barros C. S. L.
Published: March 2013

An 18-month-old Charolais cow developed depression and drooling and was submitted for necropsy after euthanasia. The cow was 1 of 50 moved between 2 farms approximately 5 days before the onset of clinical disease. Gross findings included swollen and hemorrhagic areas of malacia in the frontal, temporal, and parietal lobes of the cerebral cortex. Microscopically there was a necrotizing meningoencephalitis with intranuclear astrocytic and neuronal eosinophilic viral inclusions in the frontal, temporal, and parietal cerebral cortex as well as in the basal nuclei and thalamus. The gross and microscopic findings were consistent with necrotizing meningoencephalitis caused by bovine herpesvirus (BHV-1 or BHV-5), and the diagnosis was confirmed by detection of bovine herpesviral antigen on fresh samples of brain via fluorescent antibody test using a monoclonal antibody against BHV-1 glycoprotein C.
Selective classification and quantification model of C&D waste from material resources consumed in residential building construction
Authors: Mercader-Moyano Pilar , Ramírez-de-Arellano-Agudo Antonio
Published: March 2013

The unfortunate economic situation involving Spain and the European Union is, among other factors, the result of intensive construction activity over recent years. The excessive consumption of natural resources, together with the impact caused by the uncontrolled dumping of untreated C&D waste in illegal landfills have caused environmental pollution and a deterioration of the landscape. The objective of this research was to generate a selective classification and quantification model of C&D waste based on the material resources consumed in the construction of residential buildings, either new or renovated, namely the Conventional Constructive Model (CCM). A practical example carried out on ten residential buildings in Seville, Spain, enabled the identification and quantification of the C&D waste generated in their construction and the origin of the waste, in terms of the building material from which it originated and its impact for every m2 constructed. This model enables other researchers to establish comparisons between the various improvements proposed for the minimization of the environmental impact produced by building a CCM, new corrective measures to be proposed in future policies that regulate the production and management of C&D waste generated in construction from the design stage to the completion of the construction process, and the establishment of sustainable management for C&D waste and for the selection of materials for the construction on projected or renovated buildings.
Integration of finite element simulation and intelligent methods for evaluation of thermo-mechanical loads during hard turning process
Authors: Jafarian Farshid , Amirabadi Hossein , Sadri Javad
Published: March 2013

The machined surfaces are mainly affected by thermo-mechanical loads during machining processes. In this regard, thermal loads increase tensile residual stress and heat-affected zone; however, mechanical loads increase fatigue strength and compressive residual stress on the machined workpiece during the process. Since experimental investigation is difficult, the problem becomes more difficult if the aim is minimizing thermal loads, while maximizing mechanical loads during the hard turning process. This article presents a hybrid method based on the artificial neural networks, multiobjective optimization, and finite element analysis for evaluation of thermo-mechanical loads during the orthogonal turning of AISI H13-hardened die steel (52HRC). First, using an iterative procedure, controllable parameters of simulation (including contact conditions and flow stress) are determined by comparison between finite element and experimental results from the literature. Then, the results of finite element simulation at the different cutting conditions and tool geometries were employed for training neural networks by genetic algorithm. Finally, the functions implemented by neural networks were considered as objective functions of nondominated genetic algorithm and optimal nondominated solution set were determined at the different states of thermal loads (workpiece temperature) and mechanical loads (workpiece effective strain). Comparison between the obtained results of nondominated genetic algorithm and predicted results of finite element simulation showed that the hybrid technique of finite element method–artificial neural networks–multiobjective optimization provides a robust framework for machining simulation of AISI H13.
Experimental investigation on electrical discharge machining process with ultrasonic-assisted cryogenically cooled electrode
Authors: Srivastava Vineet , Pandey Pulak M
Published: March 2013

In this work, the effect of process parameters, namely, discharge current, pulse on time, duty cycle and gap voltage, on electrode wear ratio, material removal rate and surface roughness has been studied in electrical discharge machining process using ultrasonic-assisted cryogenically cooled electrode. Analysis of variance and regression analysis have been used to model electrode wear ratio, material removal rate and surface roughness. The analysis reveals that discharge current, pulse on time and duty cycle have significant effect on electrode wear ratio and material removal rate. Discharge current and pulse on time were found to be significant in effecting surface roughness. Confirmation experiments established that predicted values from models were in agreement with experimental findings, and optimal processing conditions have been determined for the responses. A comparative study of electrical discharge machining process using ultrasonic-assisted cryogenically cooled electrode and conventional electrical discharge machining process has been done to establish the efficacy of the new process.
The Effects of Function-Based Self-Management Interventions on Student Behavior
Authors: Hansen Blake D. , Wills Howard P. , Kamps Debra M. , Greenwood Charles R.
Published: March 2013

Children with emotional and behavioral disorders (E/BD) struggle to achieve social and academic outcomes. Many studies have demonstrated self-management interventions to be effective at reducing problem behavior and increasing positive social and academic behaviors. Functional behavior assessment (FBA) information may be used in designing effective self-management interventions. The purpose of this study was to link self-management procedures to hypothesized behavior function in three children with E/BD. Results demonstrated that self-monitoring (SM) alone could be enhanced using information derived from FBA and that consequences delivered by teachers were less effective than a self-management treatment package.
The Secret Life of an MRI Scan
Authors: Colopelnic Nicoleta
Published: March 2013

In 2008, an MRI scan was performed on my lower back after I observed severe pain in my back and left leg. In this article, by means of autoethnography, I explore the multiple meanings of the scan using both narrative and poetry. By taking the MRI scan out of the biomedical context of its production, a space opens up for the aesthetic. In the medical discourse the MRI is purely instrumental—a means of visualization that can help in the establishment of a diagnosis. In my lived experience it becomes poetry—a form of visual poetry that offers a glimpse at my inner self. This aesthetic value seems to be lost in the eyes of a physician. This piece of autoethnography strives to be a recuperation of that value.
This Pain in My Neck
Authors: Newman Joshua I.
Published: March 2013

This article offers a series of autoethnographic reflections on suffering from physical symptoms associated with a paradox of praxis. More specifically, it mediates on the musculoskeletal pangs that come with a raised critical consciousness—or what Paulo Freire refers to in his teaching as conscientização—that stands as directly incongruent to living (in) the embodied politics of an incessantly aspirational working class habitus (and various machinations of social mobility).
It’s Time to Boo
Authors: Stucky Nathan
Published: March 2013

In this piece the author questions audience behavior in the 2012 Republican primary campaign for U.S. President. Why do some ideas and performances resonate to the point of producing overt response? What underlying elements condition an audience to boo or applaud? The cultural climate of talk radio and other heated rhetoric contributes to creating conditions ripe for explosion in this context. The author develops a personal poetic response to two incidents: An audience booing a gay soldier who objected to the “Don’t Ask, Don’t Tell” policy, and an audience cheering for the death penalty.
The Distance to Delight
Authors: Tieken Mara Casey
Published: March 2013

This article documents the first stage of the qualitative research process: “entering the field.” In it, the author, a young graduate student, uses portraiture to describe her journey to find a “research site” and then establish a “research relationship” with this community, a town in rural Arkansas. This portrait offers a critical exploration of the author’s attempt to position herself in the field—locating herself through labels of race, geography, and occupation—and understand the layered identities and positions of community members. In struggling to build these relationships, the author questions the clinical language commonly used to describe the rich and complicated relationships often developed through qualitative work.
Effects of Price and User-Generated Content on Consumers’ Prepurchase Evaluations of Variably Priced Services
Authors: Noone Breffni M. , McGuire Kelly A.
Published: March 2013

The role of price in prepurchase evaluations for variably priced services has not been widely examined. Increased consumer awareness of variable pricing practices, coupled with growing availability of user-generated content (UGC) at the point of purchase in the online environment, may be changing the way that consumers use price in purchase decisions. This article examines the relative roles of price and UGC, specifically consumer reviews and aggregate consumer ratings, on consumers’ prepurchase evaluations in the context of the purchase of hotel accommodation, a service to which variable pricing is typically applied. Results indicate that, in the presence of UGC, price does not have a significant impact on perceived quality. Price and UGC have significant effects on perceived value, although consumers rely more on reviews than ratings when evaluating price–benefit trade-offs. These results suggest that, rather than simply competing on price, managers must also understand consumers’ perceptions of their firm versus the competition.
Newspaper Coverage of Implementation of the Michigan Smoke-Free Law
Authors: Kuiper Nicole M. , Frantz Kate E. , Cotant Molly , Babb Stephen , Jordan Jerelyn , Phelan Matthew
Published: March 2013

Objective. To examine whether newspaper coverage of the Michigan smoke-free law was favorable or hostile, contained positive messages that had been disseminated by public health groups, contained negative messages, and differed across regions. Method. Articles about the smoke-free law in print or online editions of Michigan newspapers the month immediately before and after the law took effect were identified and were coded for tone, positive messages contained in media outreach materials, and negative messages commonly disseminated by smoke-free law opponents. Results. A total of 303 print and online articles were identified; the majority were coded as “both positive and negative” (34%) or “mainly positive” in tone (32%). Of 303 articles, 75% contained at least one pro-law message and 56% contained at least one anti-law message. The most common pro-law messages were information about enforcement of the law (52%) and the benefits of smoke-free air (48%); the most common anti-law messages were about potential negative economic impact (36%), government intrusion/overreach (31%), and difficulties with enforcement (28%). Conclusions. Public health departments and partners play an important role in implementation of smoke-free laws by providing the public, businesses, and other stakeholders with clear and accurate rationale, provisions, and impacts of these policies.
The Application of Distally Pedicled Peroneus Brevis Muscle Flaps and Retrograde Neurocutaneous Accompanying Artery Flaps for Treatment of Bony and Soft-Tissue 3-Dimensional Defects of the Lower Leg and Foot
Authors: Hu Xiao-hua , Du Wei-li , Chen Zhong , Li Ming , Wang Cheng , Shen Yu-ming
Published: March 2013

To investigate the clinical effect of distally pedicled peroneus brevis muscle flaps and retrograde neurocutaneous flaps on treatment of bone and soft-tissue 3-dimensional defects of the lower leg and foot, the authors retrospectively studied all the patients admitted in their center in 3 consecutive years with bone and soft-tissue defects from March 2008 to February 2011; 21 patients suffering from traumatic and osteomyelitis were treated with peroneus brevis muscle flaps, for obliterating the hole-shaped bony defects after osteomyelitis debridement, and neurocutaneous flaps, for repairing associated soft-tissue defects. After thorough debridement, the average size of soft-tissue defects was 2 cm × 2 cm to 13 cm × 9 cm and that of bony defects was 2 cm × 2 cm × 2 cm to 6 cm × 3 cm × 3 cm. Neurocutaneous flaps completely survived in 20 cases, and the wounds healed at stage I; 1 case developed necrosis in the distal part of the peroneus brevis muscle flap and sural nerve flap, and the wound healed with a saphenous nerve flap. The flaps maintained good texture and shape during a follow-up of 6 to 24 months. Recurrence of osteomyelitis was not observed in any of the patients. In conclusion, distally pedicled peroneus brevis muscle flaps and retrograde neurocutaneous flaps are simple, safe, reliable, and suitable for clinical treatment of hole-shaped bony defects and reconstruction of soft-tissue defects within a single stage, especially when the 2 defects are located in different 3-dimensional spaces.
Inhaled corticosteroids and the increased risk of pneumonia
Authors: Marzoratti Lucía , Iannella Hernán A. , Waterer Grant W.
Published: March 2013

Recently it has been suggested that there is a causal association between the use of inhaled corticosteroids (ICSs) and the risk of developing pneumonia in patients with chronic obstructive pulmonary disease (COPD). An increased risk of pneumonia associated with ICS use has been seen in trials with different design, different study populations and with evidence of a dose–response relationship. However, as none of these clinical trials were originally designed to assess pneumonia risk, radiographic confirmation of pneumonia was not always obtained. The extent to which pneumonia events have been confounded with acute exacerbations of COPD is unclear. As increased pneumonia events were not associated with increased mortality it remains unclear what the clinical significance of these findings are. Further complicating the association between ICSs and pneumonia is that meta-analyses restricted to budesonide trials have not shown an increased risk of pneumonia, and no association has been seen in patients with asthma. A number of mechanisms by which ICSs could increase the risk of pneumonia have been proposed, principally related to their immunosuppressive effect. Well-designed clinical trials with predefined endpoints and objective pneumonia definitions are needed before the real risk of pneumonia conferred by ICSs can be established. In the meantime, it seems reasonable to reduce ICSs given to COPD patients to the lowest effective doses, reduce the risk in individual patients by ensuring appropriate vaccination and to be vigilant for the possibility of pneumonia in patients with COPD on ICSs as they largely overlap with those of an acute exacerbation.
Nudity in Advertising: What Influence on Attention-Getting and Brand Recall?
Authors: Lombardot Éric
Published: March 2013

Using experimentation, this paper validates the positive impact of nudity in advertising on attention getting, when model and respondent are sex opposite. It also shows that the increase in the generated attention reflects on brand recall. The paper demonstrates that the process of memorizing is, above all, emotional, and emphasizes the importance for advertisers to use a form of nudity which does not provoke rejection.
The Effect of Hyperchoice on the Consumer and the Moderating Effect of the Brand: An Application in the Jewelry Market
Authors: Larceneux Fabrice , Rieunier Sophie , Fady André
Published: March 2013

The objective of this research is to study the reactions of consumers when faced with a hyperchoice situation. Two experiments were carried out, varying the number of products displayed in a jewelry department. The results show that increasing the number of products has a positive effect on the perception of price and the sensation of choice, but a negative effect on the attractiveness of the showcase, the perception of quality, the perception of product originality, and the desire to make a choice. However, these effects of hyperchoice are largely attenuated by the presence of a brand.
Short- and Long-Term Consequences of Browsing Behavior: An Investigation into the Leisure Department of a Hypermarket
Authors: Lombart Cindy , Labbé-Pinlon Blandine
Published: March 2013

The prime goal of this research is to study the main short- and long-term consequences of browsing behavior in a retail outlet suggested by the scientific literature: non-planned purchases, time spent in the store, affective reactions, customer satisfaction and consequently, the intent to re-visit the store, to make future purchases in this store, and to recommend it. To test that, a field study was conducted in the leisure department of a hypermarket (books, comics, DVDs, CDs, video games, etc.), 599 consumers were interviewed. The results show that the main short-term consequence of browsing behavior is the time spent by consumers in the retail outlet followed by affective reactions, customer satisfaction, and non-planned purchases.
Movie Consumption Experience and Immersion: Impact on Satisfaction
Authors: Fornerino Marianela , Helme-Guizon Agnès , Gotteland David
Published: March 2013

The objective of this research is to explore whether movie consumption experience impacts satisfaction when consumers are immersed in this experiential context. First, immersion and consumption experience are defined; then, we propose a model that links theses two concepts with satisfaction. Second, we test this model by using measurement scales we developed for this purpose. Their psychometric properties are satisfactory. Three movie environments are considered in order to assess scale robustness and to highlight differences in terms of variable intensity and correlation strength. Our results show that there exists a link between immersion and emotions, and that emotions induce higher satisfaction, whatever the movie context. They also show that immersion and social interaction are linked and that this yields higher satisfaction in the case of the horror movie.
The Surprise-Delight Relationship Revisited in the Management of Experience
Authors: Vanhamme Joëlle
Published: March 2013

Practitioners firmly believe that customer delight, through surprise, offers a source of competitive advantage. Yet, competing conceptualizations, methodologies, and stimuli in existing studies of delight leave the relationship between surprise and delight ambiguous. This research note assesses the different conceptualizations of delight and offers an overview of existing empirical evidence regarding the surprise-delight relationship. According to the assessment, the conceptualization of delight as extreme satisfaction is both valid and parsimonious, which suggests its superiority. Moreover, empirical data reveal that during highly hedonic experiences, surprise indirectly influences satisfaction (through joy) and can increase satisfaction overall. This research note concludes with several suggestions for further research.
Recall of Brand Placement in Movies: Interactions between Prominence and Plot Connection in Real Conditions of Exposure
Authors: Lehu Jean-Marc , Bressoud Étienne
Published: March 2013

A product placement can be characterized by its prominence and its plot connection. This research scrutinizes the interaction between these two elements in the context of the consumer perceptual process. The results of a survey based on 32,662 exposures to brand placements in DVD movies showed that prominent and plot connected placements lead to better brand recall (spontaneous day-after recall) than prominent placements that are not plot connected, and that the latter leads to better brand recall than plot connected placements that are not prominent. The brands appearing in non prominent and non plot connected placements are the worst recalled.
The Effects of Satisfaction, Trust and Brand Commitment on Consumers' Decision to Boycott
Authors: Cissé-Depardon Karine , N'Goala Gilles
Published: March 2013

This research examines the effects of cumulative satisfaction, trust and brand commitment on consumers' decision to boycott. The study shows that their influence varies according to the type of boycott (instrumental versus expressive). Four results distinguish the two expressive boycotts considered: 1) the perceived egregiousness of the company's act and/or the message credibility totally mediate their effects on the boycott decision; 2) cumulative satisfaction enhances a contrast effect whereas brand commitment generates an assimilation effect (minimization of the fault); 3) the message credibility enhances boycott participation; 4) the volume of consumption decreases only social boycott participation. Strategic implications for consumer organizations and companies are then specified.
Definition, Measurement and Determinants of the Consumer's Willingness to Pay: A Critical Synthesis and Avenues for Further Research
Authors: Le Gall-Ely Marine
Published: March 2013

Differentiated prices, bundling, web auctions: firms' pricing practices are evolving. When there is no market, or for customized pricing, the willingness-to-pay concept seems to be interesting. This article aims at presenting a synthesis of the marketing research stream relative to willingness to pay. First, a definition of the concept is given and compared to other similar concepts, notably reference price and acceptable price. The methods of measurement are then presented, compared to those used to measure elasticity and examined. Next, the research on external determinants of willingness to pay is outlined. Finally, numerous avenues for further research are proposed.
Flagship Brand Stores within Virtual Worlds: The Impact of Virtual Store Exposure on Real-Life Attitude toward the Brand and Purchase Intent
Authors: Haenlein Michael , Kaplan Andreas M.
Published: March 2013

Virtual hyperrealities, also referred to as virtual social worlds, have experienced increasing managerial interest in recent years. Although they have also received some attention in the academic literature, the extent to which corporate presences within such environments can influence attitude toward the brand and purchase intent in real life remains unclear. Based on a survey conducted among 580 Second Life residents, we show that exposure to flagship brand stores within virtual worlds positively influences attitude toward the associated brand and real life purchase intent. We furthermore show that a user's purchase experience (shopping frequency, purchase frequency, spending per purchase) and the gratification derived from the use of their purchases have a significant moderating effect on these relationships. Our results are of managerial and theoretical importance as they provide empirical evidence for spill-over effects between virtual worlds and real life and help to develop recommendations on optimal store design within virtual social worlds.
Taboo: An Underexplored Concept in Marketing
Authors: Sabri Ouidade , Manceau Delphine , Pras Bernard
Published: March 2013

Despite the importance of taboos in contemporary societies and their impact on consumption, little research has been conducted in marketing on the concept of taboo. Building upon the literature in anthropology, sociology and psychoanalysis, this paper puts forward five defining characteristics of taboos which shed light on previous research related to taboos in marketing. This article suggests topics for future research based on taboo characteristics that influence consumer behavior and taboo perception, with emphasis on the methodological difficulties and opportunities related to this field of research.
Ambush Marketing Disclosure Impact on Attitudes toward the Ambusher's Brand
Authors: Mazodier Marc , Quester Pascale
Published: March 2013

This study examines the effect of ambush marketing disclosure on attitudes toward the ambusher's brand. The results of an experiment conducted to this end show that ambush disclosure negatively influences perceived integrity, affective response and purchase intention. Involvement in the event and attitudes toward sponsorship of an event both moderate consumers' response to ambush marketing.
Generational Concerts: In Quest of Authenticity?
Authors: Derbaix Maud , Derbaix Christian
Published: March 2013

The purpose of this research is to assess the relationship between perceived authenticity and perceived value. “Generational concerts” - built on memories - seem particularly suited to study this relationship. After a literature review of four central constructs (authenticity, value, nostalgia and generation) and four pilot studies, 404 persons - having attended such concerts - were questioned. The statistical analysis of their answers clearly shows that perceived authenticity (through its projection and singularity dimensions) does impact on the perceived value (through its hedonic and social link dimensions). This is the core contribution of this research. The mediating role of perceived value, as well as the moderating role of nostalgia proneness, are assessed. Finally, limits, alternative research perspectives, managerial implications and transferability issues are discussed.
Trust in B-to-B: Toward a Dynamic and Integrative Approach
Authors: Akrout Wafa , Akrout Houcine
Published: March 2013

The concept of trust in B-to-B has evolved in many directions. This split has created a rich diversity of research development but has also hampered the construction of a coherent theory. The purpose of this article is to present a clear and critical synthesis based upon empirical work on this concept over the last twenty years. While explaining agreements on various definitions, models and measures of the concept, we highlight their main weaknesses. New opportunities to clarify the status of trust are also proposed.
The Evidence for Generation We and Against Generation Me
Authors: Arnett Jeffrey Jensen
Published: March 2013

This article addresses the question of whether today’s emerging adults are excessively “narcissistic” as claimed by Jean Twenge and others. The answer is a decisive “no.” There is no persuasive evidence that scores on the Narcissistic Personality Inventory (NPI) have risen among college students in recent decades. In any case, the NPI is a dubious measure of narcissism, and college students are a dubious sample of emerging adults. There is evidence that today’s emerging adults have high expectations and are confident in their abilities, but these qualities should be seen as psychological resources during a life stage that is often difficult. If it were true that their narcissism was rising and that narcissism leads to impulsive behavior, then impulsive behavior would also be rising, but in fact it is diminishing across multiple indicators. As a society, we can and should do more to support emerging adults, beginning with a halt to the negative stereotypes.
The Challenge of Romantic Relationships in Emerging Adulthood
Authors: Shulman Shmuel , Connolly Jennifer
Published: March 2013

Although theories of romantic stage development suggest that youth in the period of emerging adulthood are fully capable of commitment to an intimate romantic relationship, recent research suggests that the relationships of many young people are quite different. Marriage and other forms of deep commitment are delayed while many youth engage in short-term casual encounters or in noncommitted relationships. In this article, we suggest that these data pose a challenge to stage theories that can be reconciled by considering the developmental life tasks that emerging adults must simultaneously resolve. We propose a transitional emerging adult romantic stage, coordinating romance and life plans, in which young people strive to integrate their career paths and life plans with those of a romantic partner. Resolution of this stage provides the grounding for long-term commitment to a life partner. This proposal is discussed within the perspective of life cycle and evolutionary life history theories.
KIR2DS1-dependent acquisition of CCR7 and migratory properties by human NK cells interacting with allogeneic HLA-C2+ DCs or T-cell blasts
Authors: Marcenaro Emanuela , Pesce Silvia , Sivori Simona , Carlomagno Simona , Moretta Lorenzo , Moretta Alessandro
Published: March 2013

Key Points

CCR7 uptake by NK cells can be strongly induced by major histocompatibility complex–specific activating KIRs, in particular by KIR2DS1 (specific for HLA-C2). The KIR2DS1-induced CCR7 expression on NK cells may expand greatly the contingent of alloreactive NK cells migrating to secondary lymphoid compartments after hematopoietic stem cell transplantation.
The impact of personalised therapies on respiratory medicine
Authors: Elborn J. Stuart
Published: March 2013

Stratified approaches to treating disease are very attractive, as efficacy is maximised by identifying responders using a companion diagnostic or by careful phenotyping. This approach will spare non-responders form potential side-effects. This has been pioneered in oncology where single genes or gene signatures indicate tumours that will respond to specific chemotherapies. Stratified approaches to the treatment of asthma with biological therapies are currently being extensively studied. In cystic fibrosis (CF), therapies have been developed that are targeted at specific functional classes of mutations. Ivacaftor, the first of such therapies, potentiates dysfunctional cystic fibrosis transmembrane conductance regulator (CFTR) protein Class III mutations and is now available in the USA and some European countries. Pivotal studies in patients with a G551D mutation, the most common Class III mutation, have demonstrated significant improvements in clinically important outcomes such as spirometry and exacerbations. Sweat chloride was significantly reduced demonstrating a functional effect on the dysfunctional CFTR protein produced by the G551D mutation. Symptom scores are also greatly improved to a level that indicates that this is a transformational treatment for many patients. This stratified approach to the development of therapies based on the functional class of the mutations in CF is likely to lead to new drugs or combinations that will correct the basic defect in many patients with CF.
Protein function annotation with Structurally Aligned Local Sites of Activity (SALSAs)
Authors: Wang Zhouxi , Yin Pengcheng , Lee Joslynn S , Parasuram Ramya , Somarowthu Srinivas , Ondrechen Mary Jo
Published: March 2013

Background

The prediction of biochemical function from the 3D structure of a protein has proved to be much more difficult than was originally foreseen. A reliable method to test the likelihood of putative annotations and to predict function from structure would add tremendous value to structural genomics data. We report on a new method, Structurally Aligned Local Sites of Activity (SALSA), for the prediction of biochemical function based on a local structural match at the predicted catalytic or binding site.

Results

Implementation of the SALSA method is described. For the structural genomics protein PY01515 (PDB ID 2aqw) from Plasmodium yoelii, it is shown that the putative annotation, Orotidine 5'-monophosphate decarboxylase (OMPDC), is most likely correct. SALSA analysis of YP_001304206.1 (PDB ID 3h3l), a putative sugar hydrolase from Parabacteroides distasonis, shows that its active site does not bear close resemblance to any previously characterized member of its superfamily, the Concanavalin A-like lectins/glucanases. It is noted that three residues in the active site of the thermophilic beta-1,4-xylanase from Nonomuraea flexuosa (PDB ID 1m4w), Y78, E87, and E176, overlap with POOL-predicted residues of similar type, Y168, D153, and E232, in YP_001304206.1. The substrate recognition regions of the two proteins are rather different, suggesting that YP_001304206.1 is a new functional type within the superfamily. A structural genomics protein from Mycobacterium avium (PDB ID 3q1t) has been reported to be an enoyl-CoA hydratase (ECH), but SALSA analysis shows a poor match between the predicted residues for the SG protein and those of known ECHs. A better local structural match is obtained with Anabaena beta-diketone hydrolase (ABDH), a known β-diketone hydrolase from Cyanobacterium anabaena (PDB ID 2j5s). This suggests that the reported ECH function of the SG protein is incorrect and that it is more likely a β-diketone hydrolase.

Conclusions

A local site match provides a more compelling function prediction than that obtainable from a simple 3D structure match. The present method can confirm putative annotations, identify misannotation, and in some cases suggest a more probable annotation.
MicroRNAs and their putative targets in Brassica napusseed maturation
Authors: Huang Daiqing , Koh Chushin , Feurtado J Allan , Tsang Edward WT , Cutler Adrian J
Published: March 2013

Background

MicroRNAs (miRNAs) are 20–21 nucleotide RNA molecules that suppress the transcription of target genes and may also inhibit translation. Despite the thousands of miRNAs identified and validated in numerous plant species, only small numbers have been identified from the oilseed crop plant Brassica napus (canola) – especially in seeds.

Results

Using next-generation sequencing technologies, we performed a comprehensive analysis of miRNAs during seed maturation at 9 time points from 10 days after flowering (DAF) to 50 DAF using whole seeds and included separate analyses of radicle, hypocotyl, cotyledon, embryo, endosperm and seed coat tissues at 4 selected time points. We identified more than 500 conserved miRNA or variant unique sequences with >300 sequence reads and also found 10 novel miRNAs. Only 27 of the conserved miRNA sequences had been previously identified in B. napus (miRBase Release 18). More than 180 MIRNA loci were identified/annotated using the B. rapa genome as a surrogate for the B.napus A genome. Numerous miRNAs were expressed in a stage- or tissue-specific manner suggesting that they have specific functions related to the fine tuning of transcript abundance during seed development. miRNA targets in B. napus were predicted and their expression patterns profiled using microarray analyses. Global correlation analysis of the expression patterns of miRNAs and their targets revealed complex miRNA-target gene regulatory networks during seed development. The miR156 family was the most abundant and the majority of the family members were primarily expressed in the embryo.

Conclusions

Large numbers of miRNAs with diverse expression patterns, multiple-targeting and co-targeting of many miRNAs, and complex relationships between expression of miRNAs and targets were identified in this study. Several key miRNA-target expression patterns were identified and new roles of miRNAs in regulating seed development are suggested. miR156, miR159, miR172, miR167, miR158 and miR166 are the major contributors to the network controlling seed development and maturation through their pivotal roles in plant development. miR156 may regulate the developmental transition to germination.
Reference values for glomerular filtration rate in healthy Brazilian adults
Authors: Soares Ariana Aguiar , Prates Aline Bodanese , Weinert Letícia Schwerz , Veronese Francisco Veríssimo , Azevedo Mirela Jobim de , Silveiro Sandra Pinho
Published: March 2013

Background

Glomerular filtration rate (GFR) is the best index of renal function, but age, gender and ethnicity can putatively affect its values. The aim of this study was to establish reference values for GFR in healthy Brazilian subjects while taking these factors into account.

Methods

In this cross-sectional study, GFR was measured by the 51Cr-EDTA single-injection method. GFR reference values were developed according to CLSI Guidelines for Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory (CLSI C28 protocol).

Results

The age range of the 285 healthy individuals was 19 to 70 years, 57% were females, and GFR was 106 ± 18 mL/min/1.73 m2. There was no difference between male and female GFRs (108 ± 18 vs. 104 ± 18 mL/min/1.73 m2 respectively, P = 0.134), and reference values were therefore developed from the pooled sample. GFR values were lower in subjects aged ≥45 years as compared with those younger than 45 years (98 ± 15 vs.112 ± 18 mL/min/1.73 m2, P < 0.001). Based on mean ± 2 SD, GFR reference values were 76 to 148 mL/min/1.73 m2 for subjects younger than 45 years and 68 to 128 mL/min/1.73 m2 for individuals older than 45 years, irrespective of gender.

Conclusion

The age-adjusted reference intervals reported may be reliably adopted to evaluate kidney function, since they are based on recommended standards.
Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis
Authors: Bruchmann Anja , Roller Corinna , Walther Tamara Vanessa , Schäfer Georg , Lehmusvaara Sara , Visakorpi Tapio , Klocker Helmut , Cato Andrew C B , Maddalo Danilo
Published: March 2013

Background

The Bag (Bcl-2 associated athanogene) family of proteins consists of 6 members sharing a common, single-copied Bag domain through which they interact with the molecular chaperone Hsp70. Bag5 represents an exception in the Bag family since it consists of 5 Bag domains covering the whole protein. Bag proteins like Bag1 and Bag3 have been implicated in tumor growth and survival but it is not known whether Bag5 also exhibits this function.

Methods

Bag5 mRNA and protein expression levels were investigated in prostate cancer patient samples using real-time PCR and immunoblot analyses. In addition immunohistological studies were carried out to determine the expression of Bag5 in tissue arrays. Analysis of Bag5 gene expression was carried out using one-way ANOVA and Bonferroni’s Multiple Comparison test. The mean values of the Bag5 stained cells in the tissue array was analyzed by Mann-Whitney test. Functional studies of the role of Bag5 in prostate cancer cell lines was performed using overexpression and RNA interference analyses.

Results

Our results show that Bag5 is overexpressed in malignant prostate tissue compared to benign samples. In addition we could show that Bag5 levels are increased following endoplasmic reticulum (ER)-stress induction, and Bag5 relocates from the cytoplasm to the ER during this process. We also demonstrate that Bag5 interacts with the ER-resident chaperone GRP78/BiP and enhances its ATPase activity. Bag5 overexpression in 22Rv.1 prostate cancer cells inhibited ER-stress induced apoptosis in the unfolded protein response by suppressing PERK-eIF2-ATF4 activity while enhancing the IRE1-Xbp1 axis of this pathway. Cells expressing high levels of Bag5 showed reduced sensitivity to apoptosis induced by different agents while Bag5 downregulation resulted in increased stress-induced cell death.

Conclusions

We have therefore shown that Bag5 is overexpressed in prostate cancer and plays a role in ER-stress induced apoptosis. Furthermore we have identified GRP78/BiP as a novel interaction partner of Bag5.