bluuebunny/crossref_metadata_2025 huggingface dataset:
Congenital Absence of Left Circumflex Artery: A Case Report and Review of the Literature
Authors: Fugar Setri , Issac Lydia , Okoh Alexis Kofi , Chedrawy Christelle , Hangouche Nadia El , Yadav Neha
Published: October 2017

Congenital absence of the left circumflex artery is a rare coronary anomaly with few reported cases in the literature. These patients are usually diagnosed incidentally when they undergo coronary angiography or coronary CT to rule out underlying coronary artery disease. In this article, we report a case of a 46-year-old man who was incidentally found to have a congenitally absent left circumflex artery with a superdominant right coronary artery after a workup was initiated for frequent premature ventricular contractions and regional wall motion on echocardiogram. A review of the clinical presentation, symptoms, and diagnostic modalities used to diagnose this entity is presented.
A Hybrid Vision-Map Method for Urban Road Detection
Authors: Fernández Carlos , Fernández-Llorca David , Sotelo Miguel A.
Published: October 2017

A hybrid vision-map system is presented to solve the road detection problem in urban scenarios. The standardized use of machine learning techniques in classification problems has been merged with digital navigation map information to increase system robustness. The objective of this paper is to create a new environment perception method to detect the road in urban environments, fusing stereo vision with digital maps by detecting road appearance and road limits such as lane markings or curbs. Deep learning approaches make the system hard-coupled to the training set. Even though our approach is based on machine learning techniques, the features are calculated from different sources (GPS, map, curbs, etc.), making our system less dependent on the training set.
Synthesis of a One-Dimensional Coordination Polymer of Nickel(II) Complex with a β-Oxodithioester Ligand
Authors: Rosas-Reyes Ricardo , Reyes-Ortega Yasmi , Morales-Juarez T. Jesus , Gómez-Vidales Virginia , García-Orozco Ivan
Published: October 2017

Bis-[methyl-1-hydroxy-1-cyclopentene-2-dithiocarboxylate-O,S]nickel(II) 1 was prepared starting from methyl 2-hydroxycyclopent-1-encarbodithioate ligand (CPDT) and Ni(II), and catena-[(μ2-4,4′-Bipyril)-bis-(methyl-2-hydroxy-1-cyclopentene-2-dithiocarboxylate-O,S)]nickel(ΙΙ) 2 was prepared in good yields from 1 plus 4,4′-bipyridyl (bpy) by shish-kebab methodology. The structure of 1 was confirmed by FTIR, elemental analysis, 1H NMR, UV–vis in chloroform solution and in solid, XPS, and PXRD. Compound 2 was characterized by FTIR, elemental analysis, UV–vis in chloroform solution, and in solid, XPS, PXRD, ESR, and solid state magnetization measurements. The structure of the polymer was established mostly by PXRD, ESR, and magnetization.
Administration of Rhodiola kirilowii Extracts during Mouse Pregnancy and Lactation Stimulates Innate but Not Adaptive Immunity of the Offspring
Authors: Lewicki Sławomir , Skopińska-Różewska Ewa , Brewczyńska Aleksandra , Zdanowski Robert
Published: October 2017

The use of antibiotics during pregnancy and lactation is associated with an increased risk of developmental disorders. One of the natural medicinal plants—Rhodiola kirilowii, widely used as an immunostimulant in adults—might be a good alternative to antibiotic treatment. The aim of present study was to assess whether daily oral administration of 20 mg/kg of Rhodiola kirilowii aqueous (RKW) or 50% hydroalcoholic (RKW-A) extracts affected hematological and immunological parameters of 6-week-old mouse progeny. There was no significant change in hematological parameters of blood with the exception of hemoglobin, which was significantly higher (about 4%) in RKW group. Offspring of mothers fed Rhodiola kirilowii extracts had increased percentage of granulocytes and decreased percentage of lymphocytes. These changes correlated with decreased percentage of CD3+/CD4+ T-cells (RKW and RKW-A), decrease of CD8+ cells, and increase percentage of NK cells in RKW group. In addition, both types of Rhodiola kirilowii extracts stimulated granulocyte phagocytosis and increased level of respiratory burst. In conclusion, the long-term supplementation of mouse mothers during pregnancy and lactation with RKW or RKW-A extracts affects the immune system of their progeny. These results should be taken into consideration before administration of Rhodiola kirilowii to pregnant and lactating women.
Circulating MicroRNA Profiles Differ between Hyperglycemia and Euglycemia in Coronary Heart Disease Patients
Authors: Jiang Yunyao , Liu Nan , Xue Bingjie , Hou Jincai , Lin Chengren , Ren Jianxun , Liu Jianxun
Published: October 2017

Coronary heart disease (CHD) has become one of the leading causes of death and functional impairment in the world. Hyperglycemia is associated with an increased risk of cardiovascular disease. It was speculated that miRNAs in peripheral blood were a primary parameter in discriminating CHD. The biological characteristics of coronary heart disease with hyperglycemia (HCHD) and coronary heart disease with euglycemia (ECHD) were investigated in the study. Circulating miRNAs from 26 HCHD patients and 42 ECHD patients were identified by microarrays. Compared with the healthy patients, 15 and 20 differentially expressed miRNAs were identified in HCHD and ECHD groups, respectively. Gene ontology analysis was carried out by DAVID and functional annotations of the miRNA targets related to ATP binding, cellular components, protein binding, RNA binding, DNA binding, and so on. KEGG database was used for pathway analysis. Eleven pathways were identified in both HCHD and ECHD groups. Furthermore, 13 and 3 pathways were only identified in HCHD or ECHD group, respectively. And then, miRNA-gene regulatory networks were constructed to study the relationship between differentially expressed miRNAs and genes. This suggested that hsa-let-7c-5p and hsa-miR-24-3p might have the most important function for hyperglycemia in coronary heart disease patients.
Inhibition of REDD1 Sensitizes Bladder Urothelial Carcinoma to Paclitaxel by Inhibiting Autophagy
Authors: Zeng Qinghai , Liu Jianye , Cao Peiguo , Li Jingjing , Liu Xiaoming , Fan Xiaojun , Liu Ling , Cheng Yan , Xiong Wei , Li Jigang , Bo Hao , Zhu Yuxing , Yang Fei , Hu Jun , Zhou Ming , Zhou Yanhong , Zou Qiong , Zhou Jianda , Cao Ke
Published: October 2017

Purpose: Regulated in development and DNA damage response-1 (REDD1) is a stress-related protein and is involved in the progression of cancer. The role and regulatory mechanism of REDD1 in bladder urothelial carcinoma (BUC), however, is yet unidentified.

Experimental Design: The expression of REDD1 in BUC was detected by Western blot analysis and immunohistochemistry (IHC). The correlation between REDD1 expression and clinical features in patients with BUC were assessed. The effects of REDD1 on cellular proliferation, apoptosis, autophagy, and paclitaxel sensitivity were determined both in vitro and in vivo. Then the targeted-regulating mechanism of REDD1 by miRNAs was explored.

Results: Here the significant increase of REDD1 expression is detected in BUC tissue, and REDD1 is first reported as an independent prognostic factor in patients with BUC. Silencing REDD1 expression in T24 and EJ cells decreased cell proliferation, increased apoptosis, and decreased autophagy, whereas the ectopic expression of REDD1 in RT4 and BIU87 cells had the opposite effect. In addition, the REDD1-mediated proliferation, apoptosis, and autophagy are found to be negatively regulated by miR-22 in vitro, which intensify the paclitaxel sensitivity via inhibition of the well-acknowledged REDD1–EEF2K–autophagy axis. AKT/mTOR signaling initially activated or inhibited in response to silencing or enhancing REDD1 expression and then recovered rapidly. Finally, the inhibited REDD1 expression by either RNAi or miR-22 sensitizes BUC tumor cells to paclitaxel in a subcutaneous transplant carcinoma model in vivo.

Conclusions: REDD1 is confirmed as an oncogene in BUC, and antagonizing REDD1 could be a potential therapeutic strategy to sensitize BUC cells to paclitaxel. Clin Cancer Res; 24(2); 445–59. ©2017 AACR.
CD31 Expression Determines Redox Status and Chemoresistance in Human Angiosarcomas
Authors: Venkataramani Vivek , Küffer Stefan , Cheung Kenneth C.P. , Jiang Xuejun , Trümper Lorenz , Wulf Gerald G. , Ströbel Philipp
Published: October 2017

Purpose: Angiosarcomas are soft tissue sarcomas with endothelial differentiation and vasoformative capacity. Most angiosarcomas show strong constitutive expression of the endothelial adhesion receptor CD31/PECAM-1 pointing to an important role of this molecule. However, the biological function of CD31 in angiosarcomas is unknown.

Experimental Design: The expression levels of CD31 in angiosarcoma cells and its effects on cell viability, colony formation, and chemoresistance were evaluated in human angiosarcoma clinical samples and in cell lines through isolation of CD31high and CD31low cell subsets. The redox-regulatory CD31 function linked to YAP signaling was determined using a CD31-blocking antibody and siRNA approach and was further validated in CD31-knockout endothelial cells.

Results: We found that most angiosarcomas contain a small CD31low cell population. CD31low cells had lost part of their endothelial properties and were more tumorigenic and chemoresistant than CD31high cells due to more efficient reactive oxygen species (ROS) detoxification. Active downregulation of CD31 resulted in loss of endothelial tube formation, nuclear accumulation of YAP, and YAP-dependent induction of antioxidative enzymes. Addition of pazopanib, a known enhancer of proteasomal YAP degradation resensitized CD31low cells for doxorubicin resulting in growth suppression and induction of apoptosis.

Conclusions: Human angiosarcomas contain a small aggressive CD31low population that have lost part of their endothelial differentiation programs and are more resistant against oxidative stress and DNA damage due to intensified YAP signaling. Our finding that the addition of YAP inhibitors can resensitize CD31low cells toward doxorubicin may aid in the rational development of novel combination therapies to treat angiosarcomas. Clin Cancer Res; 24(2); 460–73. ©2017 AACR.
Targeting CDH17 in Cancer: When Blocking the Ligand Beats Blocking the Receptor?
Authors: Marshall John F.
Published: October 2017

Cadherin-17 (CDH17) has been implicated as protumorigenic for many years, but mechanisms have been unclear. A Spanish team has generated antibodies to an RGD motif in CDH17 that inhibits integrin α2β1 binding to CDH17 and thereby inhibits integrin activation, tumorigenesis, and metastasis. These reagents may have therapeutic potential. Clin Cancer Res; 24(2); 253–5. ©2017 AACR.

See related article by Bartolomé et al., p. 433
Electrophysiological Evidence of the Basilar-Membrane Travelling Wave and Frequency Place Coding of Sound in Cochlear Implant Recipients
Authors: Campbell Luke , Bester Christofer , Iseli Claire , Sly David , Dragovic Adrian , Gummer Anthony W. , O'Leary Stephen
Published: October 2017

Aim: To obtain direct evidence for the cochlear travelling wave in humans by performing electrocochleography from within the cochlea in subjects implanted with an auditory prosthesis. Background: Sound induces a travelling wave that propagates along the basilar membrane, exhibiting cochleotopic tuning with a frequency-dependent phase delay. To date, evoked potentials and psychophysical experiments have supported the presence of the travelling wave in humans, but direct measurements have not been made. Methods: Electrical potentials in response to rarefaction and condensation acoustic tone bursts were recorded from multiple sites along the human cochlea, directly from a cochlear implant electrode during, and immediately after, its insertion. These recordings were made from individuals with residual hearing. Results: Electrocochleography was recorded from 11 intracochlear electrodes in 7 ears from 6 subjects, with detectable responses on all electrodes in 5 ears. Cochleotopic tuning and frequency-dependent phase delay of the cochlear microphonic were demonstrated. The response latencies were slightly shorter than those anticipated which we attribute to the subjects' hearing loss. Conclusions: Direct evidence for the travelling wave was observed. Electrocochleography from cochlear implant electrodes provides site-specific information on hair cell and neural function of the cochlea with potential diagnostic value.
Massive Upper and Lower GI Bleed from Simultaneous Primary (AL) Amyloidosis of the Stomach and Transverse Colon in a Patient with Multiple Myeloma
Authors: Khan Zubair , Darr Umar , Renno Anas , Tiwari Abhinav , Sofi Aijaz , Nawras Ali
Published: October 2017

Symptomatic primary (amyloid light-chain or AL) amyloidosis of the gastrointestinal (GI) tract is very rare. Most of the patients with symptomatic involvement of the GI tract present with altered motility, malabsorption, or bleeding. We report a case of gastric and colonic amyloidosis on anticoagulation presenting with massive upper and lower GI bleeding. A 67-year-old lady known to have multiple myeloma and AL amyloidosis on rivaroxaban presented with massive upper GI bleeding. Esophagogastroduodenoscopy showed a mass lesion (3 × 7 cm) located along the greater curvature in the body/antrum with active bleeding. Mucosal biopsies revealed amyloid deposition. She underwent partial gastrectomy and recovered well after surgery, and was discharged home on rivaroxaban. The patient presented again 4 weeks after discharge with bleeding per rectum, and a colonoscopy revealed a large mass in the proximal transverse colon with active bleeding. Biopsy of the mass showed amyloid deposition. At this point, the patient declined any further intervention. Rivaroxaban was discontinued, the rectal bleeding stopped, and she was discharged home with no further episodes of GI bleed. Amyloidosis of the GI tract presenting with massive GI bleed is extremely rare and is thought to be related to small-vessel fragility due to amyloid infiltration and impaired hemostasis caused by factor X deficiency. Even though GI bleeding with amyloidosis is spontaneous, use of anticoagulation could activate such episodes in these patients. Caution should be exercised with the use of anticoagulation in patients with amyloidosis involving the GI tract, and colonoscopy should be considered in patients with gastric amyloidosis.
Metastatic Malignancy to the Colon and Rectum: A Report of 14 Cases from One Single Institute
Authors: Lin Chi-Chun , Lin Chun-Chi , Chen Wei-Shone , Lin Tzu-Chen , Lin Jen-Kou , Jiang Jeng-Kai
Published: October 2017

Background: Metastatic malignancy occurs rarely in the colon or rectum. We presented 14 patients with colorectal metastasis (CRM). Methods: A retrospective review was conducted on a computerized colorectal tumor database at the Taipei Veterans General Hospital from January 2000 to June 2013. Results: The incidence of CRM was 0.19% (14 in 7,524 patients). There were 6 males and 8 females with a mean age of 66.9 ± 13.6 years. Origins of the CRM included lung cancers (n = 3), prostate cancers (n = 2), and others (n = 1, respectively). Clinical presentations were not specific and colonoscopic pictures were indistinguishable from primary colorectal cancers; 5 of the 9 biopsies identified metastasis. Eight patients had extracolonic metastasis and 6 patients had CRM only. Significantly better survival was observed in the CRM-only group (p = 0.037). The mean interval from the treatment of primary tumor to the diagnosis of CRM was 30.2 ± 49.0 months. The mean survival time after CRM was 24.9 ± 30.8 months. Conclusion: Clinical features and colonoscopic findings of CRM were indistinguishable from primary colorectal cancer. Histopathological review of the biopsy could be helpful in identifying the primary lesion. Surgical resection with curative intent provided longer survival in CRM-only patients.
Fazendo arte e cinema (ou “quasi-cinema”) com Hélio Oiticica
Authors: Valentin Andreas
Published: October 2017

De 1959 a 1966, Andreas Valentin foi aluno de Hélio Oiticica, que lhe ensinou técnicas de pintura, colagem com objetos encontrados e como preparar suas próprias tintas utilizando pigmentos industriais, terra, areia e cola PVA. Essas aulas eram mais um campo para a invenção e a experimentação na própria obra de Oiticica. Reencontraram-se em 1970, quando Oiticica se estabeleceu em Nova Iorque, após ter exibido seus Ninhos na exposição “Information” no MoMA. Em seu loft na Segunda Avenida – Babylonests – e em sua moradia seguinte – Hendryxsts – na Christopher Street, conceberam e realizaram projetos de cinema e fotografia. A partir das experiências pessoais do autor, foram analisados neste artigo os procedimentos e os resultados dessas colaborações.
¡Sucia Copia!
Authors: Iñigo Maria
Published: October 2017

Este texto realiza una relectura de la obra Tropicália, de Hélio Oiticica, desde la perspectiva post-colonial para revisar la versión nacional(ista) de la interpretación del trabajo y de la figura de Oiticica; para ello, se centra en una comparativa de los conceptos clave para Homi Bhabha, mimesis, ambivalencia e hibridación, en comparación con la propuesta tropicalista del artista en su atención a la favela de Rio de Janeiro, local “casi igual pero no exatamente” a la ciudad moderna occidental.
1970: pause / play
Authors: Coelho Frederico
Published: October 2017

Este artigo aprofunda a trajetória de Hélio Oiticica durante o ano de 1970. Trata-se do momento em que ele retorna de uma série de viagens e trabalhos internacionais em 1969 e se prepara para um longo período vivendo em Manhattan a partir de 1971. Nesse breve interregno carioca, Oiticica simultaneamente faz balanços de seus últimos anos de trabalho e realiza uma série de novas frentes de ação através do cinema, da música, do design e da escrita. É quando, também, o artista consolida uma nova rede de parceiros e ideias que, nos anos seguintes, se expandem em direção ao “experimental” e seus diversos desdobramentos.
Hélio Oiticica em Manhattan.
Authors: Santiago Silviano
Published: October 2017

Lembranças do convívio, na década de 1970, com o artista Hélio Oiticica, em Nova Iorque. Sua rotina de vida, seus projetos e suas reflexões sobre arte e vida.
Does Use of Bilateral Internal Mammary Artery Grafting Reduce Long-Term Risk of Repeat Coronary Revascularization?
Authors: Iribarne Alexander , Schmoker Joseph D. , Malenka David J. , Leavitt Bruce J. , McCullough Jock N. , Weldner Paul W. , DeSimone Joseph P. , Westbrook Benjamin M. , Quinn Reed D. , Klemperer John D. , Sardella Gerald L. , Kramer Robert S. , Olmstead Elaine M. , DiScipio Anthony W.
Published: October 2017

Background:

Although previous studies have demonstrated that patients receiving bilateral internal mammary artery (BIMA) conduits during coronary artery bypass grafting have better long-term survival than those receiving a single internal mammary artery (SIMA), data on risk of repeat revascularization are more limited. In this analysis, we compare the timing, frequency, and type of repeat coronary revascularization among patients receiving BIMA and SIMA.

Methods:

We conducted a multicenter, retrospective analysis of 47 984 consecutive coronary artery bypass grafting surgeries performed from 1992 to 2014 among 7 medical centers reporting to a prospectively maintained clinical registry. Among the study population, 1482 coronary artery bypass grafting surgeries with BIMA were identified, and 1297 patients receiving BIMA were propensity-matched to 1297 patients receiving SIMA. The primary end point was freedom from repeat coronary revascularization.

Results:

The median duration of follow-up was 13.2 (IQR, 7.4–17.7) years. Patients were well matched by age, body mass index, major comorbidities, and cardiac function. There was a higher freedom from repeat revascularization among patients receiving BIMA than among patients receiving SIMA (hazard ratio [HR], 0.78 [95% CI, 0.65–0.94];
P
=0.009). Among the matched cohort, 19.4% (n=252) of patients receiving SIMA underwent repeat revascularization, whereas this frequency was 15.1% (n=196) among patients receiving BIMA (
P
=0.004). The majority of repeat revascularization procedures were percutaneous coronary interventions (94.2%), and this did not differ between groups (
P
=0.274). Groups also did not differ in the ratio of native versus graft vessel percutaneous coronary intervention (
P
=0.899), or regarding percutaneous coronary intervention target vessels; the most common targets in both groups were the right coronary (
P
=0.133) and circumflex arteries (
P
=0.093). In comparison with SIMA, BIMA grafting was associated with a reduction in all-cause mortality at 12 years of follow-up (HR, 0.79 [95% CI, 0.69–0.91];
P
=0.001), and there was no difference in in-hospital morbidity.

Conclusions:

BIMA grafting was associated with a reduced risk of repeat revascularization and an improvement in long-term survival and should be considered more frequently during coronary artery bypass grafting.
Duct Stenting Versus Modified Blalock-Taussig Shunt in Neonates With Duct-Dependent Pulmonary Blood Flow
Authors: Bentham James R. , Zava Ngoni K. , Harrison Wendy J. , Shauq Arjamand , Kalantre Atul , Derrick Graham , Chen Robin H. , Dhillon Rami , Taliotis Demetris , Kang Sok-Leng , Crossland David , Adesokan Akintayo , Hermuzi Anthony , Kudumula Vikram , Yong Sanfui , Noonan Patrick , Hayes Nicholas , Stumper Oliver , Thomson John D.R.
Published: October 2017

Background:

Infants born with cardiac abnormalities causing dependence on the arterial duct for pulmonary blood flow are often palliated with a shunt usually between the subclavian artery and either pulmonary artery. A so-called modified Blalock-Taussig shunt allows progress through early life to an age and weight at which repair or further more stable palliation can be safely achieved. Modified Blalock-Taussig shunts continue to present concern for postprocedural instability and early mortality such that other alternatives continue to be explored. Duct stenting (DS) is emerging as one such alternative with potential for greater early stability and improved survival.

Methods:

The purpose of this study was to compare postprocedural outcomes and survival to next-stage palliative or reparative surgery between patients undergoing a modified Blalock-Taussig shunt or a DS in infants with duct-dependent pulmonary blood flow. All patients undergoing cardiac surgery and congenital interventions in the United Kingdom are prospectively recruited to an externally validated national outcome audit. From this audit, participating UK centers identified infants <30 days of age undergoing either a Blalock-Taussig shunt or a DS for cardiac conditions with duct-dependent pulmonary blood flow between January 2012 and December 31, 2015. One hundred seventy-one patients underwent a modified Blalock-Taussig shunt, and in 83 patients, DS was attempted. Primary and secondary outcomes of survival and need for extracorporeal support were analyzed with multivariable logistic regression. Longer-term mortality before repair and reintervention were analyzed with Cox proportional hazards regression. All multivariable analyses accommodated a propensity score to balance patient characteristics between the groups.

Results:

There was an early (to discharge) survival advantage for infants before next-stage surgery in the DS group (odds ratio, 4.24; 95% confidence interval, 1.37–13.14;
P
=0.012). There was also a difference in the need for postprocedural extracorporeal support in favor of the DS group (odds ratio, 0.22; 95% confidence interval, 0.05–1.05;
P
=0.058). Longer-term survival outcomes showed a reduced risk of death before repair in the DS group (hazard ratio, 0.25; 95% confidence interval, 0.07–0.85;
P
=0.026) but a slightly increased risk of reintervention (hazard ratio, 1.50; 95% confidence interval, 0.85–2.64;
P
=0.165).

Conclusions:

DS is emerging as a preferred alternative to a surgical shunt for neonatal palliation with evidence for greater postprocedural stability and improved patient survival to destination surgical treatment.
International Expert Consensus on Switching Platelet P2Y
12
Receptor–Inhibiting Therapies
Authors: Angiolillo Dominick J. , Rollini Fabiana , Storey Robert F. , Bhatt Deepak L. , James Stefan , Schneider David J. , Sibbing Dirk , So Derek Y.F. , Trenk Dietmar , Alexopoulos Dimitrios , Gurbel Paul A. , Hochholzer Willibald , De Luca Leonardo , Bonello Laurent , Aradi Daniel , Cuisset Thomas , Tantry Udaya S. , Wang Tracy Y. , Valgimigli Marco , Waksman Ron , Mehran Roxana , Montalescot Gilles , Franchi Francesco , Price Matthew J.
Published: October 2017

Dual antiplatelet therapy with aspirin and a P2Y
12
inhibitor is the treatment of choice for the prevention of atherothrombotic events in patients with acute coronary syndromes and for those undergoing percutaneous coronary interventions. The availability of different oral P2Y
12
inhibitors (clopidogrel, prasugrel, ticagrelor) has enabled physicians to contemplate switching among therapies because of specific clinical scenarios. The recent introduction of an intravenous P2Y
12
inhibitor (cangrelor) further adds to the multitude of modalities and settings in which switching therapies may occur. In clinical practice, it is not uncommon to switch P2Y
12
inhibitor, and switching may be attributed to a variety of factors. However, concerns about the safety of switching between these agents have emerged. Practice guidelines have not fully elaborated on how to switch therapies, leaving clinicians with limited guidance on when and how to switch therapies when needed. This prompted the development of this expert consensus document by key leaders from North America and Europe with expertise in basic, translational, and clinical sciences in the field of antiplatelet therapy. This expert consensus provides an overview of the pharmacology of P2Y
12
inhibitors, different modalities and definitions of switching, and available literature and recommendations for switching between P2Y
12
inhibitors.
Estimating the Cost of Preeclampsia in the Healthcare System
Authors: Fox Aimée , McHugh Sheena , Browne John , Kenny Louise C. , Fitzgerald Anthony , Khashan Ali S. , Dempsey Eugene , Fahy Ciara , O’Neill Ciaran , Kearney Patricia M.
Published: October 2017

To estimate the cost of preeclampsia from the national health payer’s perspective using secondary data from the SCOPE study (Screening for Pregnancy End Points). SCOPE is an international observational prospective study of healthy nulliparous women with singleton pregnancies. Using data from the Irish cohort recruited between November 2008 and February 2011, all women with preeclampsia and a 10% random sample of women without preeclampsia were selected. Additional health service use data were extracted from the consenting participants’ medical records for maternity services which were not included in SCOPE. Unit costs were based on estimates from 3 existing Irish studies. Costs were extrapolated to a national level using a prevalence rate of 5% to 7% among nulliparous pregnancies. Within the cohort of 1774 women, 68 developed preeclampsia (3.8%) and 171 women were randomly selected as controls. Women with preeclampsia used higher levels of maternity services. The average cost of a pregnancy complicated by preeclampsia was €5243 per case compared with €2452 per case for an uncomplicated pregnancy. The national cost of preeclampsia is between €6.5 and €9.1 million per annum based on the 5% to 7% prevalence rate. Postpartum care was the largest contributor to these costs (€4.9–€6.9 million), followed by antepartum care (€0.9–€1.3 million) and peripartum care (€0.6–€0.7 million). Women with preeclampsia generate significantly higher maternity costs than women without preeclampsia. These cost estimates will allow policy-makers to efficiently allocate resources for this pregnancy-specific condition. Moreover, these estimates are useful for future research assessing the cost-effectiveness of preeclampsia screening and treatment.
Are Africans Incurably Religious?
Authors: Wijsen Frans
Published: October 2017

This article analyses the debate on the invention of African Religion and the notion that Africans are incurably religious. It uses critical discourse analysis as a form of ideology critique to demonstrate how advocates and opponents of the ‘invention of African Religion’ theory construct their own social realities. Drawing on a conversation between members of the African Association for the Study of Religions the article concludes that the dilemma between the myth and reality of African Religion is false. The fact that African religion was invented does not signify that it does not exist.
The Brachyura (Crustacea: Decapoda) of the Deutschen Tiefsee-Expedition auf dem Dampfer ‘Valdivia’ 1898–1899: dates of publications and authorship
Authors: LOW MARTYN E. Y. , LEE BEE YAN , NG PETER K. L.
Published: October 2017

The consequences for the nomenclature of the Brachyura as a result of the inadvertent publication of new names in the two editions of the narrative of the Deutschen Tiefsee-Expedition auf dem Dampfer ‘Valdivia’ 1898–1899 that were published before their formal descriptions by Doflein in the scientific reports to the expedition are discussed. Both editions of the narrative are shown to have been issued in parts (Lieferungen). Accurate dates of publication for the parts of the narrative and for Doflein’s work are presented. A list of new taxon names in other groups of animals that may also have been inadvertently made available in the narrative is included.
A new species of Cyrtodactylus (Squamata: Gekkonidae) and the first record of C. otai from Son La Province, Vietnam
Authors: NGUYEN TRUONG QUANG , PHAM ANH VAN , ZIEGLER THOMAS , NGO HANH THI , LE MINH DUC
Published: October 2017

We describe a new species of Cyrtodactylus on the basis of four specimens collected from the limestone karst forest of Phu Yen District, Son La Province, Vietnam. Cyrtodactylus sonlaensis sp. nov. is distinguished from the remaining Indochinese bent-toed geckos by a combination of the following characters: maximum SVL of 83.2 mm; dorsal tubercles in 13–15 irregular rows; ventral scales in 34–42 rows; ventrolateral folds prominent without interspersed tubercles; enlarged femoral scales 15–17 on each thigh; femoral pores 14–15 on each thigh in males, absent in females; precloacal pores 8, in a continuous row in males, absent in females; postcloacal tubercles 2 or 3; lamellae under toe IV 18–21; dorsal head with dark brown markings, in oval and arched shapes; nuchal loop discontinuous; dorsum with five brown bands between limb insertions, third and fourth bands discontinuous; subcaudal scales distinctly enlarged. In phylogenetic analyses, the new species is nested in a clade consisting of C. huongsonensis and C. soni from northern Vietnam and C. cf. pulchellus from Malaysia based on maximum likelihood and Bayesian analyses. In addition, we record Cyrtodactylus otai Nguyen, Le, Pham, Ngo, Hoang, Pham & Ziegler for the first time from Son La Province based on specimens collected from Van Ho District.
Pseudanthias tequila, a new species of anthiadine serranid from the Ogasawara and Mariana Islands
Authors: GILL ANTHONY C. , TEA YI-KAI , SENOU HIROSHI
Published: October 2017

Pseudanthias tequila is described on the basis of two specimens from the Ogasawara Islands. It also is recorded from the Mariana Islands on the basis of colour photographs. The species belongs to a complex that includes P. randalli (Lubbock & Allen), P. pulcherrimus Heemstra & Randall, P. flavicauda Randall & Pyle, P. oumati Williams, Delrieu-Trottin & Planes, and a potentially new species from the Line Islands. Species within the complex are distinguished on the basis of male live colouration, morphometric details and gill-raker and scale counts. Colour photos of all five species are provided.
The new sponge species Amphoriscus pedunculatus (Porifera, Calcarea)
Authors: KLAUTAU MICHELLE , CAVALCANTI FERNANDA F. , BOROJEVIC RADOVAN
Published: October 2017

Amphoriscus is a widespread genus with 17 species. A new species was found in SE Brazil and it represents the second species of this genus in Brazilian waters. Amphoriscus pedunculatus sp. nov. has a special structure, a peduncle, to attach to the substrate. Special attachment structures are not very common in the class Calcarea but this is the third species of the genus with a peduncle. Besides peduncle, another attachment structure found in some species of Amphoriscus is the root-tuft, an attachment structure composed of diactines and anchor-like triactines or tetractines. The evolution of these attachment structures in Amphoriscus is not known but they have also been found out of this genus, suggesting that these structures appeared several times during the evolution of Calcarea or that species currently classified in different genera are in fact congeneric.
Rainfall Characteristics of Recurving Tropical Cyclones over the Western North Pacific
Authors: Deng Difei , Ritchie Elizabeth A.
Published: October 2017

A dataset of 88 recurving western North Pacific tropical cyclones from 2004 to 2015 is investigated for rainfall characteristics during their period of recurvature. The TCs are categorized into two groups based on different large-scale patterns from empirical orthogonal function analysis. Group 1 is characterized by an intense midlatitude baroclinic zone and close distance between the zone and TC, while Group 2 is characterized by a weaker midlatitude baroclinic zone and more remote distance between the zone and TC at the time of recurvature. The results show the large-scale environment has substantial impact on TC rainfall patterns. In Group 1, as the TC approaches and is embedded into the baroclinic zone, a relatively strong interaction between the TC and midlatitudes occurs, which is reflected by a rapid increase of environmental vertical wind shear and TC translation speed, the alignment of the shear vector and motion vector, and a sharp contrast of temperature and moisture. Higher rainfall and wider coverage of rainfall tends to be produced along the track after recurvature, and the rainfall pattern turns from a right-of-track (ROT) to a left-of-track (LOT) preference. Conversely, in Group 2, a relatively weak interaction between the TC and midlatitude circulation occurs, which is reflected by weaker vertical wind shear and slower TC motion, a separation of the shear vector and motion vector, and a weak gradient of temperature and moisture. The corresponding rainfall swath for Group 2 exhibits a narrower rainfall swath after recurvature. The rain pattern changes from a LOT to ROT preference.
The Cospectrum of Stress-Carrying Turbulence in the Presence of Surface Gravity Waves
Authors: Trowbridge John , Scully Malcolm , Sherwood Christopher R.
Published: October 2017

The cospectrum of the horizontal and vertical turbulent velocity fluctuations, an essential tool for understanding measurements of the turbulent Reynolds shear stress, often departs in the ocean from the shape that has been established in the atmospheric surface layer. Here, we test the hypothesis that this departure is caused by advection of standard boundary layer turbulence by the random oscillatory velocities produced by surface gravity waves. The test is based on a model with two elements. The first is a representation of the spatial structure of the turbulence, guided by rapid distortion theory, and consistent with the one-dimensional cospectra that have been measured in the atmosphere. The second model element is a map of the spatial structure of the turbulence to the temporal fluctuations measured at fixed sensors, assuming advection of frozen turbulence by the velocities associated with surface waves. The model is adapted to removal of the wave velocities from the turbulent fluctuations using spatial filtering. The model is tested against previously published laboratory measurements under wave-free conditions and two new sets of measurements near the seafloor in the coastal ocean in the presence of waves. Although quantitative discrepancies exist, the model captures the dominant features of the laboratory and field measurements, suggesting that the underlying model physics are sound.
Nanoscale Ex Situ Thermal Impulse Sensors for Structural Fire Forensics
Authors: Anderson Benjamin R. , Gese Natalie , Gunawidjaja Ray , Eilers Hergen
Published: October 2017

We developed nanoscale ex situ thermal impulse (i.e., the temperature and duration of a heating event) sensors for structural fire forensics using a mixture of two lanthanide-doped oxide precursors (precursor Eu:ZrO2 and precursor Dy:Y2O3) that undergo irreversible phase changes when heated. These changes are probed using photoluminescence (PL) spectroscopy with the PL spectra being dependent on the thermal impulse (TI) experienced by the sensors. By correlating the PL spectra to different in-lab TIs, we are able to produce a spectroscopic calibration for our sensors. This calibration allows us to determine an unknown TI of a heating event using only the PL spectrum of the heated TI sensors. In this study, we report on the calibration of these sensors for isothermal heating durations up to 600 s and isothermal temperatures up to 1273 K. Using this calibration, we also demonstrate their ability to determine an unknown TI and demonstrate their functionality when dispersed into paint, which is heated in the presence of drywall.
Laser-Induced Breakdown Spectroscopy Analysis of Lead Aerosol in Nitrogen and Air Atmosphere
Authors: Redoglio Daniele A. , Palazzo Natascia , Migliorini Francesca , Dondè Roberto , De Iuliis Silvana
Published: October 2017

In this work, laser-induced breakdown spectroscopy (LIBS) is applied for quantitative measurements of Pb in aerosols. In order to investigate the carrier gas role and, in particular, the effect of O2 addition to the gas itself, measurements are carried out in nitrogen and air atmosphere. Aerosol particles are produced by nebulizing Pb(CH3COO)2 * 3H2O aqueous solutions of known concentration and the atomic line of 405.8 nm is detected as Pb signature. The plasma generated with the laser pulse is characterized in terms of plasma temperature and electron density, showing no substantial differences with the two carrier gases used. The behavior of the LIBS signal as a function of the delay time with respect to the laser pulse is investigated changing the environmental conditions and, in particular, the Pb concentration values. The different trends registered in the case of relatively short (up to 20 μs) and long delay time, resulting to be the same whatever the Pb concentration value, could have a significant effect on the calibration curve performed in different experimental conditions.
S’approprier la laïcité malgré la tourmente sociale: la présence d’une posture « optimiste critique » chez des femmes musulmanes portant le hijab au Québec
Authors: Lavoie Bertrand
Published: October 2017

Les défenseurs d’une interdiction du port du hijab pour des employées de l’État fondent en grande partie leur position sur la thèse selon laquelle le fait de porter ce signe religieux signifie de facto un non-respect de la laïcité. En portant un voile, une femme musulmane participerait à la manifestation publique d’une priorité accordée à des obligations religieuses au détriment de ses obligations citoyennes, tout en étant plus ancrée dans une identité religieuse que dans une identité civique. L’objectif du présent article est de démontrer la faiblesse de cette thèse en montrant que des employées musulmanes de l’État québécois portant le hijab peuvent se positionner favorablement vis-à-vis de la laïcité. Nous pensons que des femmes musulmanes portant le hijab et travaillant pour l’État ont plutôt tendance à se dire en accord avec les fondements de la laïcité en adoptant une posture d’« optimiste critique », en étant à la fois méfiantes mais optimistes. La démonstration repose sur une étude sociologique réalisée auprès de 30 femmes musulmanes portant un hijab, employées de l’État québécois ou songeant à le devenir.
Enhancing Pediatricians’ Behavioral Health Competencies Through Child Psychiatry Consultation and Education
Authors: Walter Heather J. , Kackloudis Gina , Trudell Emily K. , Vernacchio Louis , Bromberg Jonas , DeMaso David R. , Focht Glenn
Published: October 2017

The objective of this study was to assess feasibility, utilization, perceived value, and targeted behavioral health (BH) treatment self-efficacy associated with a collaborative child and adolescent psychiatry (CAP) consultation and BH education program for pediatric primary care practitioners (PCPs). Eighty-one PCPs from 41 member practices of a statewide pediatric practice association affiliated with an academic medical center participated in a program comprising on-demand telephonic CAP consultation supported by an extensive BH learning community. Findings after 2 years of implementation suggest that the program was feasible for large-scale implementation, was highly utilized and valued by PCPs, and was attributed by PCPs with enhancing their BH treatment self-efficacy and the quality of their BH care. After participation in the program, nearly all PCPs believed that mild to moderate presentations of common BH problems can be effectively managed in the primary care setting, and PCP consultation utilization was congruent with that belief.
Test of a Conceptual Model to Explain Television Exposure of Head Start Children
Authors: Swindle Taren M. , Jarrett Diane , McKelvey Lorraine M. , Whiteside-Mansell Leanne , Conners Edge Nicola A. , Kraleti Shashank
Published: October 2017

Excessive television (TV) viewing by children can lead to negative health and developmental outcomes. Using structural equation modeling, this study tests a conceptual model to understand social and familial factors associated with TV exposure among a sample of 767 Head Start families with children between the ages of 3 and 5 years. Fit statistics suggested that the overall model provided an acceptable fit to the observed data. Specifically, significant structural paths suggest that parents’ social support affects child TV exposure. Additionally, lower levels of social support were associated with significantly greater parental stress, which also predicted child TV exposure. Findings suggest that physicians and other team members of the patient-centered medical home may benefit from broad-based interventions that address familial factors to combat excess TV exposure among children. Urging parents to turn off the TV could fail to address the underlying causes of child TV exposure.
Penis-whirling and pie-throwing: Norm-defying and norm-setting drama in the creative industries
Authors: Sørensen Bent Meier , Villadsen Kaspar
Published: October 2017

This article explores the drama performed around a self-proclaimed ‘anti-establishment’ executive at a Danish film company, Zentropa. The company prides itself on being against the existing ‘elitist’ and commercialized Danish film industry. Inspired by the thesis that modern capitalism develops by incorporating the critiques directed against it, the article analyses how Zentropa’s Chief Executive Officer invests a ‘progressive’, counter-cultural spirit in his management practices. We describe how a ‘freethinking’ and ‘subversive’ CEO uses his dramatized performances to exercise an authority that violates employees’ privacy and involves public displays of disrespect. We further examine how employees use impression management to cope with norm-violating management practices, including sexual provocations and the dramatic, unjustified dismissal of an employee. In the context of these disruptions, we analyse how order is reestablished through dramaturgical cycles of symbolic events, including sacrifice. In particular, the study provides insights into how theatrically staged, norm-defying performances both disrupt the organization and allow managerial power to be reinstituted. It also demonstrates that anti-establishment management involves and rests upon the occasional exercise of traditional managerial hierarchy and control. Theoretically, the article develops a dramatist perspective, combining Goffman’s symbolic interactionism and Burke’s dramatism to offer a framework for understanding norm-transgressive management in modern organizations.
Prevalence and factors associated with PTSD, anxiety and depression symptoms in Haitian migrants in southern Brazil
Authors: Brunnet Alice E , Bolaséll Laura T , Weber João LA , Kristensen Christian H
Published: October 2017

Background:

Prevalence rates of mental health disorders in migrants are controversial. The socio-historical and economic background of the host country may play an important role in the mental health status of migrants. As studies are mostly conducted in developed countries, researching migration in developing countries may add important information to scientific literature.

Aims:

This study aims to investigate the prevalence and factors associated with posttraumatic stress disorder (PTSD), anxiety and depression symptoms in Haitian migrants in southern Brazil.

Methods:

The sample comprises 66 participants selected from four different sites in three cities of a Brazilian southern state. Participants fulfilled a sociodemographic questionnaire, as well as instruments investigate traumatic events; post-migration difficulties and symptoms of PTSD, anxiety and depression. Linear regression models were utilized to investigate factors associated with PTSD, anxiety and depression symptoms.

Results:

PTSD prevalence in the sample was 9.1%. Depression and anxiety symptoms were in the clinical range of 10.6%–13.6% of participants, respectively. A number of traumatic events, acculturation difficulties, discrimination and low social support were associated with the investigated mental health disorders.

Conclusion:

The results point to the importance of public policies in promoting better social and mental health support for migrants. Providing information to the Brazilian population about migration may improve receptiveness in the host society.
Research on the characteristics of mixed traffic flow based on an improved bicycle model
Authors: Dong Peng , Wang Xifu , Yun Lifen , Fan Hongqiang
Published: October 2017

Mixed traffic flow is a main feature of urban traffic in developing countries. Mixed bicycle flow includes human-powered and electric-powered bicycles and plays an important role in this mixed traffic flow. In mixed bicycle flow, cyclist behavior is flexible and variable. Cyclists move arbitrarily in the road and may influence the vehicle flow at intersections. Therefore, we first propose an improved bicycle model that can reproduce the main features of cyclist behavior, such as overtaking and self-protection. Then a simulation model based on the improved bicycle model is proposed to research the characteristics of mixed traffic flow in intersections. The conflict avoidance rules are then applied in the simulation model to eliminate traffic accidents. The simulation results indicate that the improved bicycle model is practical and that the density–velocity diagram of bicycle flow is similar to real traffic data. The existence of bicycle flow decreases vehicle velocity and worsens traffic flow in mixed traffic flow. However, the influence of bicycle flow might disappear at a particular vehicle density.