bluuebunny/crossref_metadata_2025 huggingface dataset:
Donor Selection Criteria for Inclusion in Stanford TMC v2
Authors: Horning Aaron , Lin Yiing
Published: July 2020

HubMAP Donor and Tissue Eligibility Criteria Form Version 1.0 Effective Date: 1/1/2019 HuBMAP TMCs: Stanford / Washington University, St. Louis Caltech / University of Washington
Protocols involving the pdMAX plasmid v1
Authors: Murakami Manabu
Published: July 2020

The pdMAX system enables inducible expression of two different genes with one prokaryotic DNA expression plasmid. The complete pdMAX protocol involves four steps. 1. Subcloning in arabinose unit Ligation of a blunt-end DNA fragment into the EcoRV site of pgMAX (arabinose unit) 2. Subcloning in IPTG unit Ligation of a blunt-end DNA fragment into the SmaI site of pdMAX (IPTG unit) 3. Prokaryotic analysis (E. coli) Either arabinose (10 mM) or IPTG (1.0 mM) could be used for gene expression. 4. α-Complementation assay For the α-complementation assay, a blunt-end DNA fragment (369 bp) of the α-peptide sequence of the lacZ gene was amplified using Pfu DNA polymerase with specific primers (AlphaFor, CAGGAAACAGCTATGAC; AlphaRev, CCATTCGCCATTCAGGCTGCGCAA) and pBluescript KS- plasmid (Agilent Technologies) as a template. PCR-amplified product was inserted at the EcoRV (in arabinose unit) or SmaI (IPTG unit) site of pdMAX.DNA ligation was performed using standard ligation techniques (Takara DNA Ligation kit ver. 2.1; Takara, Otsu, Japan). After 16 h of incubation on LB agar plates containing ampicillin (ABPC; 150 μg/mL), X-gal (1 mM), and IPTG (1 mM) or arabinose (10 mM), colonies were observed.
SOCIAL INNOVATIONS IN EDUCATION – DRIVERS OF HUMAN CAPITAL DEVELOPMENT
Authors: Osetskyi V. , Kyrylchuk О. , Savchuk N.
Published: July 2020

The article analyzes the theoretical approaches to understanding the essence of the category “social innovations” in the educational space and shows what role they play in the development of human capital. The authors define “social innovations” and explore existing approaches to their classification. The importance of higher education in the development of human capital and the introduction of new social initiatives have been demonstrated. The necessity to carry out deep reforms of the education system and focus on additional missions of universities with a focus on inclusive development, research and entrepreneurship are substantiated. The role of social initiatives in increasing the competitiveness of Ukrainian universities is highlighted.
Review of Reconfigurable Microstrip Patch antenna for Wireless Application
Authors: Pandey Shraddha , Vyas Pankaj
Published: July 2020

In recent time, world have seen a rapid growth in wireless communication. Development in antenna from single band to dual band and multi band had made the antenna system more compact. A frequency reconfigurable microstrip antenna using a PIN diode for multiband operation is using many application and hot research area. In this paper, reconfigurable microstrip patch antennas and their types like frequency, polarization, radiation pattern and gain are described.
A PUBLICIDADE NAS REDES SOCIAIS E SEUS IMPACTOS NA CULTURA DO CONSUMISMO
Authors: Silva Carlos Mendes Monteiro da , Brito Dante Ponte de
Published: July 2020

As redes sociais são ferramentas de comunicação e de troca de informações de alta relevância na sociedade contemporânea. Bilhões de usuários possuem perfil ativo nas mídias digitais e, por este motivo, as empresas têm se interessado cada vez mais em ocupar estes espaços virtuais para divulgação de anúncios publicitários. Neste contexto, este trabalho objetiva fazer uma análise da publicidade nas redes sociais e seus impactos na cultura do consumismo, apurando suas consequências no comportamento do consumidor, sobretudo no que tange à responsabilização por sua utilização indevida. Para tanto, é necessário realizar, antes, um estudo sobre as redes sociais e seu papel de destaque na sociedade hodierna e também sobre o regime jurídico da publicidade. Diante do exposto, faz-se necessário investir no direito à informação e à educação do consumidor, a fim de que o mesmo seja capaz de identificar e se proteger da influência de anúncios ilícitos divulgados nas redes sociais e, consequentemente, mitigar o avanço do consumismo.
Éditorial / Editorial
Authors: Einboden Rochelle
Published: July 2020

Special Issue Editorial: 7th In Sickness & In Health International Research Conference: Technologies, Bodies & Health Care F rom 7-9 June 2018 we gathered on the Rozelle Campus of the University of Tasmania, inSydney, Australia to extend the tradition of the In Sickness and In Health Conferences. These conferences were born from like-minded individuals (Helsinki-7) who were interested in creating an international network of critical health scholars and scholarship in relation to power, practice and ethics in health care. At the 7th In Sickness and In Health: Technologies, Bodies and Health Care we came from around the world to engage in critical discussions regarding technology and its interface with the social and material body in health and illness. Nowadays, technologies have permeated and contributed to an ideology of effi ciency across the social, critical conversations are needed more than ever. With opportunities for critical discussions becoming increasingly rare and vitally important, I am very pleased to see us continue the conversation with an even wider audience through this special edition of Aporia – The Nursing Journal. Thank you to all authors who have contributed to this special edition of Aporia – The Nursing Journal. I also extend my gratitude to the Editor-in-Chief of Aporia – The Nursing Journal, Professor Dave Holmes, for the opportunity to continue engaging in critical conversations about the assemblages and relations between technologies, bodies and health. I hope that each and every one of you will fi nd the content of these papers thought provoking and inspiring. I look forward to continuing our conversations at the 8th conference 10-12 June, 2020: People, Origin and the End of the Universe, Lleida, Spain. https://isihconference.com/isih-2020/ Rochelle Einboden, RN, PhD Conference Chair In Sickness & In Health Conference
Taxa de decomposição foliar de espécies utilizadas em sistemas agroflorestais
Authors: Leal de Sousa Iara Rayana , Pauletto Daniela , Lopes Lucas Sérgio de Sousa , Rode Rafael , Peleja Vanessa Leão , Freitas Bruna Bandeira de
Published: July 2020

Os sistemas agroflorestais (SAFs) promovem a sustentabilidade do agroecossistema através das interações energéticas e da ciclagem de nutrientes por meio da produção e decomposição de biomassa sobre o solo. O objetivo deste trabalho foi avaliar a decomposição foliar de espécies utilizadas na adubação verde e de interesse econômico em sistemas agroflorestais. O estudo foi realizado no SAF experimental da Universidade Federal do Oeste do Pará (UFOPA). Analisou-se a decomposição foliar de seis espécies, sendo cacau (Theobroma cacao L.), cumaru (Dipteryx odorata (Aubl.) Forsyth) e pimenta-do-reino (Piper nigrum L.) consideradas de interesse econômico e feijão-de-porco (Canavalia ensiformis (L.) DC.), gliricídia (Gliricidia sepium (Jacq.) Walp.) e guandú (Cajanus cajan (L.) Huth) consideradas espécies de adubação verde. Para acompanhar a decomposição, utilizou-se o método de litter bags com o experimento alocado nos períodos mais chuvoso e menos chuvoso. Os dados de massa foliar remanescente foram analisados estatisticamente pelo teste Tukey e ajustados por meio de equação não-linear para obtenção da constante de decomposição (k) e tempo de meia-vida (t1/2). As espécies apontadas para adubação verde apresentaram as maiores de taxas de decomposição ao final do experimento, nas quais a gliricidia e feijão de porco obtiveram as maiores taxas. Dentre as espécies escolhidas por interesse econômico, a pimenta do reino apresentou retorno de nutrientes ao solo superiores as espécies cumaru e cacau. O período seco obteve perda de massa mais lenta que o período chuvoso.
Moscas-das-frutas (Diptera: Tephritidae) associadas com mangueiras no Seridó Oriental da Paraíba
Authors: Alves Emanoel Da Costa , Dantas Jair Ferreira , Freire José Lucínio de Oliveira , Araujo Elton Lucio , Macedo Luciano Pacelli Medeiros de
Published: July 2020

As moscas-das-frutas são responsáveis por causarem danos à cultura da mangueira (Mangifera indica L. - Anacardiaceae) com prejuízos socioeconômicos. Assim, objetivou-se com esse trabalho relatar as espécies de moscas-das-frutas, seus índices faunísticos e flutuação populacional em mangueiras das variedades Espada e Maranhão, na região Seridó Oriental do estado da Paraíba. O trabalho foi desenvolvido em um pomar de mangueira das variedades Espada e Maranhão, não tecnificado, na comunidade Várzea Verde, município de Frei Martinho, Paraíba, Brasil. As moscas-das-frutas foram coletadas com o auxílio de armadilhas McPhail, utilizado proteína hidrolisada à 5%, como atrativo alimentar. Foram calculados os índices faunísticos (dominância, abundância, frequência e constância). A flutuação populacional foi estabelecida através do índice de Mosca/Armadilha/Dia, correlacionando-a com as variáveis climáticas, temperatura e precipitação pluvial. Foram capturados 1.364 exemplares de moscas-das-frutas, representados por seis espécies, Anastrepha obliqua (Macquart, 1835), A. dissimilis Stone, 1942, A. sororcula Zucchi, 1979, A. zenildae Zucchi, 1979, A. distincta Greene, 1934 e Ceratitis capitata (Wiedemann, 1824), sendo o maior número de espécimes pertencentes ao gênero Anastrepha. A temperatura e a precipitação pluvial influenciaram negativamente nas populações de moscas-das-frutas no período de frutificação.
Youth Policy of the European Union and “May 1968”
Authors: Bulavintsev N.V.
Published: July 2020

The article considers the problem in the history of the European Union: what date can be considered the beginning of a youth policy? In reviews of the history of youth policy in the European Union one can frequently find the date “1968”, when a wave of student protests swept across Europe, as a starting point. The article explores the reasons for this role of the May 1968 events. The article gives both a formal and symbolic answer to the question set in the study. Analyzing other studies of the European Union history and documents of the European Communities, the factual and symbolic side of the issue is considered. Using the concept of “places of memory”, coined by Pierre Nora, the author analyzes the symbol of 1968 protests in relation to the history of youth policy of the European Union. Interpreting “1968” as a “place of memory” for European politics, the author comes to the conclusion that the European Union’s youth policy has two starting points: the formal one, which is directly related to the institutionalization of the “youth” social group as a direct object of the European Union’s policy, and the symbolic, which is associated with the recognition of youth as a political entity.
Em terreno movediço: entre a cultura e a instituição da educação popular / Into quicksands: between the culture and the institution of popular education
Authors: Valdanha Neto Diógenes
Published: July 2020

A Educação Popular se expressa em diversas práticas dos movimentos populares. Circundar alguns de seus aspectos teóricos mais centrais pode contribuir para maior assertividade e fecundidade das ações educacionais. Frente a isso, este ensaio teórico tem o objetivo de argumentar sobre a centralidade do conceito antropológico de cultura para a existência da Educação Popular na condição de práxis educacional, e discutir limites e possibilidades de sua institucionalização. Parte-se da discussão conceitual mais aprofundada do conceito antropológico de cultura, sobretudo a partir do diálogo de Paulo Freire com outros autores. Em seguida, são discutidas algumas possibilidades e limitações decorrentes dessa centralidade – o Marco de Referência da Educação Popular para as Políticas Públicas (2014) é discutido como parâmetro para a questão. O artigo é finalizado em meio ao reconhecimento da perene situação de movimento da Educação Popular como paradigma educacional e maior expressão de sua potência criadora.Palavras-chave: Educação Popular. Paulo Freire. Políticas Públicas. Cultura. Educação do Campo. ABSTRACT: Popular education is expressed in various practices of popular movements. Framing some of its most central theoretical aspects can contribute to greater assertiveness and fruitfulness of educational actions. Therefore, this article aims to argue about the centrality of the anthropological concept of culture for the existence of Popular Education as an educational praxis, and to discuss limits and possibilities of its institutionalization. It starts from a deeper conceptual discussion of the anthropological concept of culture, especially from Paulo Freire's dialogue with other authors. Then, some possibilities and limitations arising from this centrality are discussed – the Popular Education Framework for Public Policies (2014) is discussed as a parameter for the issue. The article ends with the recognition of the enduring situation of movement in the educational paradigm of Popular Education as its greater expression of creative power.Keywords: Popular education. Paulo Freire. Public policy. Culture. Rural Education.
Hipertrofia turystyki miejskiej – geneza i istota zjawiska
Authors: Kowalczyk-Anioł Joanna
Published: July 2020

W artykule zaprezentowano autorskie ujęcie hipertrofii turystyki miejskiej, jak i genezę tego zjawiska w kontekście przemian współczesnego miasta. Przedstawiono, na podstawie literatury, logikę włączania i wykorzystywania turystyki w transformacji miejskiej gospodarki i przestrzeni oraz przypisane jej role w polityce miejskiej. Pokazano ponadto w różnych kontekstach geograficznych procesy i zjawiska towarzyszące współczesnej turystyfikacji miasta, w tym zyskującą na znaczeniu finansjalizację zasobów mieszkaniowych.
Edificios híbridos. Potenciadores de urbanidad en la ciudad contemporánea, una visión desde la experiencia de Steven Holl
Authors: Amorelli Sebastián , Bacigalupi Lucía
Published: July 2020

Uno de los principales desafíos del urbanismo contemporáneo es el constante aumento demográfico, y la fragmentación y dispersión territorial que resultan en una pérdida de vida urbana. La densificación funcional ha sido reconocida como una de las herramientas capaces de contrarrestar estos fenómenos mediante la acumulación de actividades dentro de un mismo contenedor, creando así un edificio híbrido con el potencial de influenciar el desarrollo de urbanidad en su entorno. Estos edificios son híbridos porque los usos contenidos se potencian y complementan, escapan de la escala arquitectónica ejerciendo una importante influencia a nivel urbano, e incorporan el espacio público de la ciudad a su propia estructura. Gracias a la capacidad que estos edificios tienen de hacer frente a un gran número de las problemáticas contemporáneas, los edificios híbridos han adquirido una mayor popularidad en las últimas décadas. El arquitecto Steven Holl es una de las personalidades que más han indagado en el estudio y diseño de estos edificios, reconociendo su potencial como condensadores de actividad y urbanidad. En su obra, Holl utiliza la porosidad como herramienta de integración de la arquitectura y el urbanismo, de forma de generar estructuras capaces de reproducir la intensidad y complejidad de la ciudad.
LGBTQ Youth-Serving Organizations: What Do They Offer and Do They Protect Against Emotional Distress?
Authors: Eisenberg Marla E. , Gower Amy L. , Watson Ryan J. , Porta Carolyn M. , Saewyc Elizabeth M.
Published: July 2020

School-based support organizations for lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ) youth have been well studied as a protective factor, but little research has explored LGBTQ youth-serving organizations in community settings, which may be similarly beneficial. The current study describes the features and services of community-based LGBTQ youth-serving organizations and tests how the extent of LGBTQ youth-serving organizational resources is associated with emotional distress among LGBQ youth in those communities. Data from the 2013 Minnesota Student Survey were merged with community-level data from the LGBTQ Environment Inventory for multilevel logistic regression, to test whether living in an area (i.e., 15-minute drive-time buffer) with some or many LGBTQ organizational resources was associated with lower odds of internalizing symptoms, self-harm, suicidal ideation, and suicide attempts among 2454 LGBQ youth in 81 communities. Website searching identified 25 LGBTQ youth-serving organizations in the state, offering an average of 3.8 conveniences and services (range: 1–6). Approximately three-quarters of LGBQ youth lived in an area with no LGBTQ youth-serving organizations and approximately 15% had many organizational resources. Living in an areas with resources was associated with lower odds of emotional distress, even after adjusting for metropolitan location. For example, the odds of high internalizing symptoms were significantly lower for girls living in communities with many LGBTQ youth organization resources compared to those living in areas with no resources (OR = 0.83, CI = 0.70–0.99). Findings suggest that living in an area with organizational resources for LGBTQ may be beneficial for the emotional well-being of LGBQ adolescents in those areas.
COVID-19: Crónica de una Infodemia. La segunda pandemia
Authors: Gaitán Russo Rosana del V.
Published: July 2020

--
Conferencias de prensa y COVID-19: explorando la respuesta gubernamental mexicana desde la comunicación en salud
Authors: Llano Guibarra Ninón Irene , Aguila Sánchez Julio César
Published: July 2020

Introducción: La pandemia de la COVID-19 ha puesto a prueba la capacidad de los gobiernos –y de los sistemas políticos y sanitarios– para manejar situaciones excepcionales, donde la comunicación cumple un rol fundamental. Esto demanda desplegar procesos comunicativos coordinados, coherentes, asertivos y eficientes. Objetivo: El presente artículo tiene el objetivo de caracterizar las conferencias de prensa de la Secretaría de Salud de México durante la segunda fase de la pandemia de COVID-19 en el país, por ser el principal espacio de comunicación para atender la crisis. Metodología: Fueron analizadas las 28 conferencias correspondientes a la segunda fase de la pandemia a través del análisis de contenido en el programa FileMaker, versión 18. Resultados: El análisis demuestra que además de la información técnica, la información sobre la gestión gubernamental de la crisis ocupa un lugar privilegiado dentro de la conferencia. Conclusión: Este espacio de comunicación oficial tomó en consideración los elementos estructurales de vulnerabilidad que intervienen en la propagación de la pandemia, lo cual guarda una estrecha relación con el llamado a la responsabilidad individual y colectiva que hace el Estado.
COVID-19 Pandemic Outbreak May Compromise Proper Management for Critically Ill Trauma Patients
Authors: Soares do Brito Joaquim , Spranger André , Almeida Paulo , Fernandes Pedro , Sarmento Marco
Published: July 2020

N/a.
EDUKASI PENETAPAN WAKTU HENTI OBAT HEWAN BAGI PETERNAK SAPI PERAH DI KABUPATEN SIDOARJO, JAWA TIMUR
Authors: Lazuardi Mochamad , Hermanto Bambang , Restiadi Tjuk Imam
Published: July 2020

Food safety and the phenomenon of antimicrobial resistance have caused world problems since the beginning of 2019, while the abuse and use of antibiotic problems in fresh animal origin products (PSAH) are still common. The purpose of this training activity is to provide direct competency strengthening for farmers who are closely related to the use of antibiotics where PSAH obtained will be directly related to human health. A total of 50 dairy farmers were conducted training using the method of learning by doing and doing by learning using 3 stages of activities, namely (1) strengthening competencies face to face, (2) continued training in counting downtime of veterinary medicines using props, ending the application of tetracycline residue examination at PSAH and examples of milk residues. The results of the training show that there is mastery of training materials by the average farmer farmers controlled by 85%.AbstrakKeamanan pangan dan fenomena antimicroba resistance menjadikan persoalan dunia sejak awal tahun 2019, sementara penyalahgunaan dan penggunasalahan antibiotika pada produk segar asal hewan (PSAH) masih sering terjadi. Tujuan kegiatan pelatihan ini adalah untuk memberikan penguatan kompetensi langsung terhadap peternak yang erat kedekatannya dengan penggunaan antibiotika dimana PSAH yang diperoleh akan langsung berhubungan dengan kesehatan manusia. Sejumlah 50 peternak sapi perah dilakukan pelatihan menggunakan metode learning by doing dan doing by learning menggunakan 3 tahapan kegiatan yaitu (1) penguatan kompetensi secara tatap muka, (2) dilanjutkan pelatihan penghitungan waktu henti obat hewan menggunakan alat peraga, diakhiri penerapan pemeriksaan residu tetrasiklin pada PSAH dan contoh adanya residu apada susu. Hasil pelatihan menunjukkan terdapat penguasaan materi pelatihan oleh petani peternak rerata dikuasai 85%.
PEMANFAATAN GOOGLE CALENDAR UNTUK PEMBUATAN KALENDER AKADEMIK DI SMP MIFTAHUL ULUM SURABAYA
Authors: Faroqi Asif , Suryanto Tri Lathif Mardi
Published: July 2020

One of the developments in information and communication technology that currently is mobile technology. Various Google production services are known as Google Apps. One of the google applications is google calendar which is a schedule management web. This application can be adopted for making school academic calendars. The advantage of using google calendar for making academic calendars is that information created on the google calendar can be shared and synchronized with smart phones owned by teachers at Miftahul Ulum Middle School Surabaya. Through the academic calendar, the teachers now have a schedule of activities for one semester to help teachers when they want to plan their teaching and learning activities. In addition, information stored on mobile phones will be safer from potential damage or loss. The purpose of the implementation of this service program is to socialize the use of the google calendar to teachers for the school academic calendar. In this activity, as many as twenty-seven teachers attended and participated in the training actively and enthusiastically.AbstrakSalah satu perkembangan dari teknologi informasi dan komunikasi yang saat ini adalah teknologi mobile. Melalui teknologi mobile, kini seseorang dapat menikmati berbagai layanan internet kapan saja dan dimana saja melalui ponsel pintar mereka. Google sebagai salah satu perusahaan teknologi informasi terbesar di dunia memiliki layanan internet yang dapat dimanfaatkan oleh para penggunanya. Berbagai layanan tersebut dikenal dengan sebutan google apps. Salah satu aplikasi google adalah google calendar yang merupakan web pengelolaan jadwal. Aplikasi ini dapat diadopsi untuk pembuatan kalender akademik sekolah. Kelebihan menggunakan google calendar untuk pembuatan kalender akademik adalah informasi yang dibuat pada google calendar dapat dibagi dan disinkronkan dengan ponsel pintar yang dimiliki oleh guru-guru di SMP Miftahul Ulum Surabaya. Melalui kalender akademik tersebut, para guru kini memiliki jadwal kegiatan apa saja selama satu semester sehingga membantu para guru ketika ingin merencanakan kegiatan belajar mengajarnya. Selain itu, informasi yang tersimpan di ponsel akan lebih aman dari potensi rusak maupun hilang. Tujuan Pelaksanaan program pengabdian ini adalah untuk sosialisasi pemanfaatan google calendar kepada para guru untuk pembuatan kalender akademik sekolah. Dalam kegiatan tersebut, sebanyak dua puluh tujuh guru hadir dan mengikuti pelatihan dengan aktif dan antusias.
PEMANFAATAN TANAMAN OBAT SEBAGAI UPAYA SWAMEDIKASI DI KELURAHAN TANGKILING KECAMATAN BUKIT BATU KOTA PALANGKA RAYA
Authors: Maryani Maryani , Ratnasari Ida , Handayani Tutwuri
Published: July 2020

Training on the utilization of medicinal plants for residents in Tangkiling Sub-District, Bukit Batu Subdistrict, Palangka Raya is expected to be able to increase knowledge in an effort to self-medication with medicinal plants. The activity is carried out by organizing two types of training related to self-medication using medicinal plants and monitoring the activities carried out. The results of monitoring and evaluation have shown that there has been an increase in consumption of red ginger and turmeric in the family and in activities in the community. The transfer of knowledge about the benefits of the types of family medicinal plants in the surrounding environment and the making of herbal medicine has also taken place from trainees to residents who did not attend the training informally. Medicinal plants that were distributed to the training participants during the service activities were also maintained well in the yard of the house. Overall empowerment activities for residents of Kelurahan Tangkiling, Bukit Batu Subdistrict, Palangka Raya City, Central Kalimantan have been going well.AbstrakPelatihan pemanfaatan tanaman obat terhadap warga di Kelurahan Tangkiling Kecamatan Bukit Batu Kota Palangka Raya diharapkan mampu meningkatkan pengetahuan dalam upaya melakukan swamedikasi dengan tanaman obat. Pelaksanaan kegiatan dilakukan dengan menyelenggarakan dua jenis pelatihan yang berkaitan dengan swamedikasi menggunakan tanaman obat dan melakukan pemantauan terhadap kegiatan yang dilakukan. Hasil monitoring dan evaluasi yang telah dilakukan menunjukkan bahwa telah terjadi peningkatan konsumsi wedang jahe merah dan kunyit asam dalam keluarga dan dalam kegiatan-kegiatan di lingkungan warga. Transfer ilmu tentang manfaat jenis-jenis tanaman obat keluarga yang ada di lingkungan sekitar dan pembuatan jamu juga telah terjadi dari peserta pelatihan kepada warga yang tidak mengikuti pelatihan secara informal. Tanaman obat yang dibagikan kepada peserta pelatihan saat kegiatan pengabdian dilakukan juga masih terpelihara dengan baik di pekarangan rumah. Secara keseluruhan kegiatan pemberdayaan pada warga Kelurahan Tangkiling, Kecamatan Bukit Batu Kota Palangka Raya Kalimantan Tengah telah berjalan dengan baik.
Impact of Grip Strength in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib
Authors: Endo Kei , Kuroda Hidekatsu , Kanazawa Jo , Sato Takuro , Fujiwara Yudai , Abe Tamami , Sato Hiroki , Kooka Youhei , Oikawa Takayoshi , Sawara Kei , Takikawa Yasuhiro
Published: July 2020

Although sarcopenia is characterized by a loss of muscle strength and skeletal muscle mass, few studies have evaluated the effect of muscle strength on hepatocellular carcinoma (HCC) patients. We separately evaluated the impact of sarcopenia-related factors (grip strength [GS] and the skeletal muscle index [SMI]) on the survival among lenvatinib-treated unresectable HCC (u-HCC) patients. This single-center cohort study was conducted at a university hospital. The study population included 63 lenvatinib-treated u-HCC patients managed between April 2018 and April 2020. A decreased GS and decreased SMI were found in 21 (33.3%) and 22 (34.9%) patients, respectively. The overall survival (OS) of the normal GS group was significantly higher than that of the decreased GS group, while that of the normal and decreased SMI groups did not differ markedly. There were no significant differences in the progression-free survival between the normal GS and decreased GS groups or the normal SMI and decreased SMI groups. A multivariate Cox proportional hazards model showed that ALBI2b (hazard ratio [HR] 4.39) and a decreased GS (HR 3.55) were independently associated with an increased risk of poor prognosis. In addition to the hepatic functional reserve, a decreased GS was a poor prognostic factor in lenvatinib-treated u-HCC patients.
The Impact of Climate Change and Global Warming on Utilization of Crop Genetic Resources
Authors: Damania Ardeshir B.
Published: July 2020

Abstract: A large number of collecting expeditions were launched in regions of ‘centers of diversity’ and hundreds of thousands of sample have been collected and stored in gene banks as ‘genetic resources’. So far, only a small number of the samples have been evaluated for their biotic and abiotic stress tolerance. Now, their time to become useful has come. A new global phenomenon has arisen – climate change. The crop genetic resources and their wild progenitors that have survived countless years of changing environment during the last 11,000 years could harbor genes that may be useful under the new growing conditions and environmental factors thrown up by climate change and global warming. With the deployment of modern bio-engineering techniques selected genes or gene fragments can be transferred from genetic resources to modern varieties of crop plants to make them well-prepared to mitigate the effects of global warming and climate change. The latter is the most serious issue facing plant breeders today. New pests and diseases could affect crop production. These review paper discusses various impacts and issues as a result of this phenomenon and suggest ways to safeguard our most important crops through better management of crop plant genetic resources in the near future.
PENTINGNYA PENDEKATAN KETERAMPILAN PROSES PADA PEMBELAJARAN IPA DI MADRASAH
Authors: Mahmudah Laely
Published: July 2020

Pendekatan keterampilan proses penting untuk diaplikasikan pada pembelajaran IPA di Madrasah. Keunggulan pendekatan keterampilan proses di dalam proses pembelajaran antara lain, peserta didik terlibat langsung dengan objek nyata sehingga dapat mempermudah pemahaman peserta didik terhadap materi pelajaran, peserta didik menemukan sendiri konsep-konsep yang dipelajari, melatih peserta didik untuk berpikir lebih kritis, melatih peserta didik untuk bertanya dan terlibat lebih aktif dalam pembelajaran, mendorong peserta didik untuk menemukan konsep-konsep baru, memberi kesempatan kepada peserta didik untuk belajar menggunakan metode ilmiah. Guru dalam pembelajaran IPA menggunakan pendekatan keterampilan proses sebaiknya membuat perencanaan yang baik dan membuat LKPD agar pembelajaran lebih terarah, efektif, dan berpengaruh positif terhadap hasil belajar peserta didik.

 

Abstract

THE IMPORTANCE OF PROCESS SKILL APPROACH ON SCIENCE LEARNING IN MADRASA: Process skills approach is essential to be applied to science learning in Madrasa. Excellent process skills approach in the learning process, such as students directly involved with the real object so as to facilitate students understanding of the subject matter, the students find their own concepts studies, to train students to think more critically, to train students to ask and be more active in learning, encourage students to discover new concepts, provide an opportunity for students to learn to use the scientific method. Teachers in learning science apply process skills approach should make a good planning and making worksheet for learning more targeted, effective, and positive influence on the learning outcomes of students.

 
MENGEMBANGKAN KREATIVITAS SISWA MELALUI KONSEP PEMBELAJARAN DI LUAR KELAS (OUTDOOR STUDY)
Authors: Krisdaniastutik Faria , Hadi Nur
Published: July 2020

Sasaran utama dalam kerangka sistem dan aktivitas persekolahan di antaranya mempersatukan pendidikan dan kreativitas peserta didik. Tujuannya untuk menumbuhkembangkan potensi-potensi yang dimiliki anak didik termasuk potensi memberikan respon kreatif terhadap hal-hal sekitar kehidupannya. Ada yang beranggapan bahwa bila daya kreativitas peserta didik rendah, maka secara pedagogis ada yang kurang pas dalam kerangka sistem dan aktivitas persekolahan. Pendidikan bukan hanya bagaimana cara untuk memperoleh pengetahuan. Namun, pendidikan merupakan upaya untuk meningkatkan pemahaman, sikap, kreativitas dan keterampilan serta perkembangan diri anak. Kemampuan atau kompetensi ini diharapkan dapat dicapai melalui berbagai proses pembelajaran di sekolah. Salah satu proses pembelajaran yang digunakan untuk mencapai kompetensi diatas adalah melalui pembelajaran di luar kelas (outdoor study). Artikel ini merupakan kajian library research yang menampilkan wacana dan sumber-sumber pustaka dalam menjawab pertanyaan yang terfokus dalam tema yang penulis ambil, yakni menampilkan bagaimana konsep penerapan pembelajaran di luar kelas, bagaimana lingkungan dan alam berperan sebagai sumber belajar pembelajaran di luar kelas, apa kelebihan dan kelemahan dari pembelajaran di luar kelas, serta bagaimana cara meningkatkan kreativitas siswa melalui pembelajaran di luar kelas.
PHILOSOPHICAL BASIS OF EDUCATION PERSPECTIVE PHILOSOPHY OF PRAGMATISME AND IMPLICATIONS IN LEARNING METHOD
Authors: Falah Riza Zahriyal
Published: July 2020

The writing of this article aims to reveal the philosophical basis of education according to the philosophy of pragmatism. It also reveals the influence of pragmatism in educational thinking, especially in the method of learning. Pragmatism as one of the educational concepts born in America, provides solutions to educational problems that in their view can not be solved traditional philosophy. Pragmatism tries to reconstruct more practical and down-to-earth educational practices, not long-winded in the metaphysical discussion of things. n practice, pragmatism emphasizes that the foundation of education is experience. Knowledge gained by humans comes from experience, not from innate talent. Truth in the view of pragmatism is a practical consequence. Education in schools according to pragmatism is a place for learners to gain experience as well as experience gained outside school. Education according to pragmatism should also take into account changes in society, because that is where students will return. Learning given to learners does not emphasize systematic teaching materials, but experiences and ways to process them. Problem solving and democracy are the main principles in learning according to pragmatism. By relying on problem solving and democratic, learners will be able to capture and process and formulate the results of his experience well.
Food Insecurity, Diet Quality, Home Food Availability, and Health Risk Behaviors Among Emerging Adults: Findings From the EAT 2010–2018 Study
Authors: Larson Nicole , Laska Melissa N. , Neumark-Sztainer Dianne
Published: July 2020

Objectives. To examine emerging adults’ experiences of food insecurity in relation to measures of diet quality, food literacy, home food availability, and health behaviors.

Methods. We used EAT 2010–2018 (Eating and Activity over Time) study data on 1568 participants who completed surveys as adolescents in 2009 to 2010 and follow-up surveys in 2017 to 2018 (mean age = 22.0 ±2.0 years; 58% female). At baseline, participants were recruited from 20 urban schools in Minneapolis–St Paul, Minnesota. Food insecurity was defined by emerging adult report of both eating less than they thought they should and not eating when hungry because of lack of money.

Results. The prevalence at follow up of experiencing food insecurity in the past year was 23.3% among emerging adults. Food insecurity was associated with poorer diet quality (e.g., less vegetables and whole grains, more sugar-sweetened drinks and added sugars), lower home availability of healthy foods, skipping breakfast, frequently eating at fast-food restaurants, binge eating, binge drinking, and substance use (all P < .01).

Conclusions. Assistance programs and policies are needed to address food insecurity among emerging adults and should be coordinated with other services to protect health.
Development of a Korean Culture-Friendly Olfactory Function Test and Optimization of a Diagnostic Cutoff Value
Authors: Ha Jong-Gyun , Kim Jinwon , Nam Jae Sung , Park Jeong Jin , Cho Hyung-Ju , Yoon Joo-Heon , Kim Chang-Hoon
Published: July 2020

Objectives. Cultural familiarity and safety must be considered when assessing olfactory ability. The YSK olfactory function (YOF) test is a new olfactory function test using culturally familiar odorants to Koreans.Methods. The YOF test comprises three subtests for threshold (T), discrimination (D), and identification (I). The identification test included eight universal and four Korean culture-friendly odorants, which were selected considering eight major functional groups. Data were obtained from 1,127 subjects over 19 years old. Subjects were classified as having normosmia (n=542), hyposmia (n=472), and anosmia (n=113) by self-reported olfactory function. The YOF test and the Korean version of the Sniffin’ stick test (KVSS-II) were performed on the same day in random order. Diagnostic cutoffs for anosmia and hyposmia were calculated using the Youden index (J).Results. The mean values for each T/D/I subtest and the total TDI score were as follows: normosmia (T, 4.6±2.3; D, 8.6±2.1; I, 11.1±1.7; TDI score, 24.2±4.5); hyposmia (T, 3.3±2.2; D, 7.1±2.5; I, 9.2±3.1; TDI score, 19.5±6.4); and anosmia (T, 1.7±1.2; D, 5.1±2.5; I, 5.0±3.2; TDI score, 11.8±5.6). The correlation coefficients between the YOF test and KVSS-II were 0.57, 0.65, 0.80, and 0.86 for T, D, I, and the TDI score, respectively (P<0.001). The diagnostic cutoffs were a TDI score ≤14.5 (J=0.67) for anosmia and 14.5(TDI score ≤21.0 (J=0.38) for hyposmia. The diagnostic efficacy of the YOF test (area under the curve [AUC], 0.88) was equivalent to that of the KVSS-II (AUC, 0.88; P=0.843; DeLong method).Conclusion. The YOF test is a new olfactory test using safe and Korean culture-friendly odorants. It showed equivalent validity with the conventional olfactory function test. Furthermore, the YOF test provides information on the major functional groups of odorants, potentially enabling a more comprehensive interpretation for patients with olfactory disorders.
The finding of a rare in the Black Sea polychaete Ctenodrilus serratus (Schmidt, 1857) (Annelida, Cirratulidae)
Authors: Lisitskaya E. V. , Boltachova N. A.
Published: July 2020

In July 2019, three polychaetae specimens of the genus Ctenodrilus were found in oyster cages on silted oyster shells. The cages from a mussel-and-oyster farm located at the outer roadstead of Sevastopol Bay were suspended at a depth of 6–8 m. The bottom soil under the mussel-and-oyster farm is silted sand, and the depth is of 16 m. During the sampling, water temperature was of +23 °C, and the salinity was of 17.7 ‰. Thus, according to morphological characteristics, polychaetae we found should be classified as Ctenodrilus serratus (Schmidt, 1857). Photographs of alive and fixed polychaetae, chaetae patterns, and a schematic representation of their number by segments are presented. At the beginning of the XX century, a single specimen of this species was found in the Black Sea.
IMPROVE YIELD AND DOWNY MILDEW RESISTANCE OF F1 MADURA MAIZE HYBRIDS
Authors: Amzeri Achmad , Badami Kaswan
Published: July 2020

Maize production in Madura Island is low. The study aimed to evaluate the agronomic performances (flowering age, harvesting age, and yield), heterosis effect, and resistance to downy mildew disease of F1 Madura maize hybrids. Ten F1 maize hybrids and seven respective parents were evaluated at the experimental center of the Agro-Technology Study Program of Agriculture Faculty, the University of Trunojoyo Madura, from July to December 2017. The experiments were arranged in a randomized block design, three replications, with a 50–100 plant population per unit. The parents were T12, T16, G10, G14, E02, Td04 and L1 genotypes having resistance to downy mildew (Peronosclerospora maydis). The results showed that the flowering age of the F1 Madura maize hybrids ranged 35–39 days, the harvesting age was 74–81 days, and the yield ranged from 2.90–6.40 t ha-1. Three hybrids showed the highest yield (T12 x L1 = 6.40 t ha-1, T16 x L1 = 5.42 t ha-1, and E02 x L1 = 5.90 t ha-1), and resistance to downy mildew, i.e. T12 x L1 (26.67%), T16 x L1 (26.67%), and E02 x L1 (26.67%). Two hybrids showed the highest heterosis values for yield, i.e. T12 x L1 (65.80%) and E02 x L1 (54.65%). The study suggests that three F1 Madura maize hybrids (T12 x L1, T16 x L1 and E02 x L1) are prospective to be developed further for high yield and resistance to downy mildew.
Evolution of an Archean fan delta and its implications for the initiation of uplift and deformation in the Barberton greenstone belt, South Africa
Authors: Drabon Nadja , Heubeck Christoph E. , Lowe Donald R.
Published: July 2020

The 3.28 to 3.23 Ga Mapepe Formation in the Barberton greenstone belt, South Africa, marks the initiation of widespread tectonic uplift and deformation after nearly 300 million years of predominantly basaltic and komatiitic magmatism under largely anorogenic conditions. This rapid transition is recorded in the eastern Barite Valley area by the buildup of a fan delta. Well-exposed sections there reach about 450 m thick and can be divided (from base to top) into five informal members: Member 1 is dominated by mudstone with subordinate banded ferruginous chert and turbiditic sandstone representing a deep-water basinal environment. Member 2 is composed of siltstone and fine-grained sandstone reworked by currents to form laminated, cross-laminated, and low-angle cross-stratified sediments in an off-shore or possibly subtidal fan-delta-front setting. Member 3 overlies member 2 unconformably; it is composed of predominantly coarse-grained, cross-bedded sandstone interbedded with laminated mudstone deposited on shallow-subtidal to intertidal flats along the fringe of a small fan delta in which putative microbial mats covered low-energy upper tidal flats. Fan-delta sedimentation was subsequently overwhelmed by the influx of dacitic pyroclastic sediments of member 4. Orthochemical sedimentary rocks including barite, jaspilite, and chert deposited on top of this shallow-water bank. Mappable facies changes towards the northeast and southwest document the transition from bank top into major mass-transport deposits of fan-delta slope facies and then into basinal deposits. Subsequent relative sea-level rise resulted in the return to below-wave-base deposition of turbiditic sandstone, mudstone, and banded ferruginous chert of member 5.

The lenticular geometry of units in cross section, mineralogical immaturity, and high variability in provenance of the coarse-grained units imply short-distance transport of sediment derived from strata of the underlying Onverwacht Group and from local penecontemporaneous dacitic volcanism. Throughout the greenstone belt, Mapepe rocks in several structural belts display fan deltas developed adjacent to small, local uplifts. While the cause of these uplifts has generally been associated with the initiation of geodynamically driven tectonic activity in the BGB, it is possible that a cluster of large meteorite impacts may have directly or indirectly triggered the crustal deformation.
REVITALISASI FUNGSI MASJID SEBAGAI PUSAT PENGAJARAN ALQURAN MELALUI PELATIHAN MANAJEMEN MADRASAH DINIYYAH DI DUSUN SELUNGGUH KABUPATEN MAGETAN
Authors: Natsir Ahmad , Rahmawati Amalia , Nitasari Estiqomah Ayum
Published: July 2020

ABSTRAK Masyarakat  dusun  Selungguh  yang  rata-rata  mempunyai  mata  pencaharian  berupa  pertanian menggantungkan  kehidupan  mereka  pada  siklus  alam.  Hal  inilah  yang  membuat  mereka secara  naluri  mendekatkan  diri  mereka  kepada  Tuhan  yme.  sebagai  pemilik  alam  raya  agar senantiasa  memberikan    tanaman  yang  subur  serta  hasil  yang  baik.  Rupa-rupanya  hal  ini tidak  didukung  dengan  estafet  keilmuan  baca  tulis  Alquran  kepada  generasi  selanjutnya. Menurunnya  intitusi pengajaran  yang  ada  di masjid  Al-Falah  membuat  para  warga  berinisiatif mejalankan  program  pengajaran  Alquran  secara  privat  di  masing-masing  rumah.  Hal  inilah yang  menjadikan  peneliti  bekerjasama  dengan  tokoh  agama  dan  masyarakat  dusun  Selungguh untuk  mengadakan  pelatihan  manajemen  madrasah  diniyyah  dalam  rangka  revitalisasi  fungsi masjid  sebagai  pusat  pengajaran  Alquran.  Dengan  sambutan  yang  hangat  dari  warga masyarakat  peneliti  mengundah  tokoh  yang  berkompeten  dalam  bidang  ini  untuk  memberikan pelatihan.  Dengan  materi  dan  kemapuan  yang  mumpuni  masyarakat  tergerak  untuk  kembali mengagendakan  program  pengajaran  Alquran  di  masjid  yang  mereka  sudah  punyai.  Dengan dampingan  yang  intens  selama  satu  bulan  penuh.  Akhirnya  pemusatan  pengajaran  Alquran  di masjid  al-Falah berjalan dengan baik  dan  disambut oleh  masyarakat dengan antisias.
Single-cell RNA seq analysis identifies the biomarkers and differentiation of chondrocyte in human osteoarthritis
Authors: Zhang Xiaolu , Huang Nianlai , Huang Rongfu , Wang Liangming , Ke Qingfeng , Cai Liquan , Wu Shiqiang
Published: July 2020

Background： Single-cell RNA sequencing (scRNA-seq) was recently adopted for exploring molecular programmes and lineage progression patterns of pathogenesis of important diseases. In this study, scRNA-seq was used to identify potential markers for chondrocytes in osteoarthritis (OA) and to explore the function of different types of chondrocytes in OA.Methods：Here we aimed to identify the biomarkers and differentiation of chondrocyte by Single-cell RNA seq analysis. GeneOntology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were used to identify the function of candidate marker genes in chondrocytes. Protein–protein interaction (PPI) network was constructed to find the hub genes in 3 types of chondrocyte respectively. We also used qRT-PCR to detect the expression level of the candidate marker genes in different types of chondrocyte. Results： In this study, we characterized the single-cell expression profiling of 480 chondrocyte samples and found hypertrophic chondrocyte (HTC), homeostatic chondrocyte (HomC) and fibrocartilage chondrocyte (FC) respectively. The results of GO and KEGG analysis showed the candidate marker genes made specific function in these chondrocytes to regulate the development of OAs respectively. We further revealed the differential expression of top 10 marker genes in 3 types of chondrocyte. The marker genes of HTC and FC were mainly expressed in their cell subset respectively. The marker genes of HomC did not have obviously differential expression among different types of chondrocyte. Last, we predicted the key genes in each cell subset. CD44, JUN and FN1 were predicted tightly related to the proliferation and differentiation of chondrocytes in OAs and could be regarded as biomarkers to estimate the development of OA. Conclusion： Our results provide new insights into exploring the roles of different types of chondrocyte in OA. The biomarkers of chondrocyte were also valuable for estimating OA progression.