bluuebunny/crossref_metadata_2025 huggingface dataset:
A New Food-grade Coenzyme Q10 Formulation Improves Bioavailability: Single and Repeated Pharmacokinetic Studies in Healthy Volunteers
Authors: Petrangolini Giovanna , Ronchi Massimo , Frattini Elisabetta , De Combarieu Eric , Allegrini Pietro , Riva Antonella
Published: September 2019

Background:

Coenzyme Q10 is a fundamental endogenous factor involved in cell energy
production that shows protective properties in oxidative stress, mainly in skeletal and heart muscle.
Coenzyme Q10 supplementation appears to benefit athletes in strenuous training and in the elderly,
demonstrating ant-inflammatory properties by reducing inflammatory cytokines. Improved absorption
of coenzyme Q10 via a new delivery system would represent an important step forward in the use of
coenzyme Q10 as a dietary supplement.

Objective:

The aim of the study was to evaluate the solubility and oral absorption in human healthy
volunteers of a new food grade coenzyme Q10 phytosome formulation.

Methods:

Solubility studies were performed in vitro in simulated gastrointestinal fluids; human studies
were conducted in healthy volunteers to evaluate oral absorption in a Single dose study, in comparison
with the coenzyme Q10 capsules, and in a repeated study at two increasing doses.

Results:

The highest solubility shown by coenzyme Q10 phytosome in simulated intestinal fluids results
in an improvement in oral absorption of coenzyme Q10 in healthy volunteers, three times more than the
coenzyme Q10 according to AUC (area under the time/concentration curve) values. When two increasing
doses (one and two capsules) were administered to healthy volunteers within a two-week schedule,
the plasmatic levels of coenzyme Q10 resulted in 0.864±0.200 μg/ml (Mean±S.D.+41%) and
1.321±0.400 μg/ml (+116%), respectively versus baseline (0.614±0.120 μg/ml one capsule,
0.614±0.160 μg/ml two capsules). This detected dose-related bioavailability of coenzyme Q10 phytosome
was even observed with no alterations in vital signs, neither in the physical examination nor in
ECG, and no changes of clinical and biochemical parameters were observed.

Conclusion:

These findings, taken together, support the safety profile and significantly improved coenzyme
Q10 oral absorption in humans with this new phytosome delivery formulation.
Targeting Mutant KRAS for Anticancer Therapy
Authors: Chen Fengqian , Alphonse Martin P. , Liu Yan , Liu Qi
Published: September 2019

:

Over the past decades, designing therapeutic strategies to target KRAS-mutant cancers, which is one of the most frequent mutant oncogenes among all cancer types, have proven unsuccessful regardless of many concerted attempts. There are key challenges for KRAS-mutant anticancer therapy, as the complex cellular processes involved in KRAS signaling has present. Herein, we highlight the emerging therapeutic approaches for inhibiting KRAS signaling and blocking KRAS functions, in hope to serve as a more effective guideline for future development of therapeutics.
Suicide phenomenon on bebandem village: a review on religious and socio-cultural
Authors: Santika I Putu Gde , Triguna Ida Bagus Gde Yudha , Utama I Wayan Budi
Published: September 2019

There is an ideational culture. It can be interpreted as a basis for thinking that the final reality is nonmaterial. It cannot be captured on eye-catching. The theory also stated that this world is seen as an illusion, and temporary or can be interpreted as an imperfect and incomplete aspect of reality. The next theory is the sensory culture theory. If the previous theory assumes that we must balance between the interests of the world and the hereafter, on the theory of sensory culture, on the contrary, we must be more oriented towards worldly interests. The material world experience with our senses is only reality that exists. The final theory is mixed culture theory. This theory is an affirmation between ideational and sensory theory. The theories are used to explain the causes of related suicide to sensate culture. The cultural dynamic theory was chosen as one of the cornerstones of this research. Due to the theory is consists of types of cultural mentality. Thus, this theory is used to explain the cultural conditions and situations that occur in Bebandem Village and the conditions and situations experienced by individuals who commit suicide through interviews, observation and so forth. Data collected are observation techniques, in-depth interviews, and document study techniques.
Teaching strategies and technology integration in developing blended learning of applied mathematics subject
Authors: Karma I Gede Made , Darma I Ketut , Santiana I Made Anom
Published: September 2019

Applied Mathematics is a basic skill that determines the success of students in pursuing their education in the Department of Mechanical Engineering. Besides having to understand concepts and be able to solve cases according to the topics taught, students are also required to be able to solve mathematical engineering problems in the application of mechanical engineering. This makes it a difficult subject for the majority of students. This difficulty is overcome by applying blended learning. This is done by integrating curriculum design with strategy and use of learning technology so that innovation and teaching excellence are formed to support the learning process of students. Learning strategies that can be applied include explanations of concepts, problem-based learning, problem-solving and case discussions. This learning strategy is supported by multimedia technology and internet-based, namely video tutorials, discussion of material and examples of online-based cases and online discussion forums. The process of face-to-face learning in class is still being carried out. The key to the success of this learning lies in the ability to create interactions between students and fellow students, with teachers, with the community, with the material with the use of existing technology.
Konsolidacija pamćenja u primarnoj nesanici
Authors: Pedić Paula
Published: September 2019

Pretpostavlja se da spavanje ima brojne funkcije, a jedna od njih je i konsolidacija pamćenja. Konsolidacija pamćenja je neurološki proces putem kojega se stvaraju trajni tragovi u dugoročnom pamćenju. Postavlja se pitanje što se događa s pamćenjem ako je spavanje poremećeno? Jedan od najčešćih poremećaja spavanja je primarna nesanica. Korpus dosadašnjih istraživanja pamćenja u primarnoj nesanici je ograničen, a znanstvena metoda ovih istraživanja različita, pa ne čudi da su dosadašnja istraživanja proceduralnog i deklarativnog pamćenja osoba s primarnom nesanicom polučila nesukladne rezultate. Cilj rada je prikazati odnos pamćenja i spavanja na primjeru primarne nesanice te sistematizirati rezultate dosadašnjih istraživanja.
Extremely severe vitamin B12 deficiency
Authors: Pupić-Bakrač Ana , Pervan Antea , Pupić-Bakrač Jure , Končurat Jakov
Published: September 2019

Aim: Vitamin B12 (cobalamin) is nutrient from the vitamin B complex family. It is essential in the human body for deoxyribonucleic acid (DNA) synthesis and for cellular energy production. Vitamine B12 deficiency is decrease in its serum concentration below 220 pmol/L, and it can be present in various range of hematologic and systemic symptoms and signs. The aim of this article is to provide extensive information on extreme forms of deficiency of vitamin B12. Case report: 83-year-old men presented with fatigue, intolerance of physical activity, vertigo, paresthesia in fingers, dispersion, epigastric pain, vomitting and loss of apetite. Vital parameters were within normal range, and physical examination did not reveal any patological findings, except icterus of sclera and subicterus of skin. Urgent laboratory findings showed erythrocytes 1.18 x 1012/L (4.34-5.72 x 1012/L), hemoglobin 50 g/L (138-175 g/L), mean corpuscular volume (MCV) 123.6 fL (83.0-97.2 fL), vitamin B12 < 61 pmol/L (220-665 pmol/L). Patient started parenteral therapy with vitamin B12. After 5 days, rapid increase in reticulocyte count was observed, with haemogram stabilization within 6 weeks. In a follow-up period of two years, the patient had no symptoms. Conclusion: We presented patient with extreme deficiency of vitamin B12. Screening for vitamin B12 deficiency should be established in each patient with macrocytic anemia, even with slightly elevated MCV.
The First Thing We Do…Let’s Kill the Kill Switches (With Apologies to William Shakespeare)
Authors: McEvoy Sharlene A.
Published: September 2019

A device used by lenders to assure payment of debt may endanger lives and be a violation of the Fair Debt Collection Practices Act. This paper examines the use of “kill switches” on vehicles and laws designed to eliminate or curb them.
EFFECT OF LOVASTATIN NANO DRUG DELIVERY SYSTEM ON BONE MINERAL DENSITY (BMD) AND BIOMECHANICAL PROPERTIES OF TIBIA BONES OF WISTAR RATS
Authors: KAUR RAMANDEEP , Ajitha Makula
Published: September 2019

Objective: In the present study, transdermal nanoemulsion (NE) gel of lovastatin was investigated for its anti-osteoporosis effect on the long bones of rat i.e. tibia.

Methods: Male wistar rats (n=30, weighing 180-200g) were taken for this study and grouped as: 1) control (normal saline daily), 2) Dex (dexamethasone sodium; 25 mg/kg subcutaneously twice a week), 3) Dex+LNG5 (lovastatin nanoemulsion gel; 5 mg/kg/d transdermally daily), 4) Dex+LNG10 (lovastatin nanoemulsion gel; 10 mg/kg/d transdermally daily), and 5) Dex+ALN (alendronate sodium; 0.03 mg/kg/d orally daily). All the treatments were carried out for 60 d. At the end of the experiment, all animals were anesthetized using diethyl ether and collected blood samples from retro-orbital venous plexus of rats in dry eppendorf tubes followed by the sacrifice of animals by cervical dislocation method and collected tibia bones of both the legs for analysis.

Results: Bone formation biomarkers (OC: osteocalcin, b-ALP: bone-specific alkaline phosphatase, PINP: N-terminal propeptides of type I procollagen) were significantly improved and resorption biomarkers (CTx: C-terminal cross-linking telopeptides of type-I collagen, TRAcP5b: isoform 5b of tartarate resistant acid phosphatase) were significantly reduced in the LNG5 (p<0.05) and LNG10 (p<0.05) treatment groups when compared to Dex. In vivo anti-osteoporotic results demonstrated the formation of new bone in osteoporotic rat tibias. Biomechanical strength testing demonstrated increased load-bearing capacity of rat tibias in the treated animals in comparison with the osteoporotic group (p<0.05 for LNG5 and p<0.01 for LNG10).

Conclusion: Thus, the transdermal NE gel formulation of lovastatin demonstrated the greater potential for the treatment of osteoporosis.
A organização retórica do artigo de opinião no contexto do vestibular
Authors: Ramos Wiliam Cesar , Bicudo Cintia , Di Raimo Luciana Cristina Ferreia Dias
Published: September 2019

Nesta pesquisa, realizamos uma análise documental de vinte artigos de opinião produzidos no vestibular de inverno de 2016 da Universidade Estadual de Maringá (UEM), considerados ótimos pela Comissão Central do Vestibular Unificado (CVU), com o objetivo de identificar a sua estrutura retórica e contrastá-la com a do artigo de opinião produzido no contexto jornalístico. Pautamo-nos na definição de gênero proposta por Bakhtin (1997, 2006), no modelo CARS (Create A Research Space) de Swales (1990), e na adaptação do modelo CARS, proposto por Oliveira (2004) para o gênero Artigo de opinião. Os resultados revelam que a estrutura retórica dos artigos produzidos no contexto do vestibular apresenta diferenças com relação à estrutura retórica daqueles produzidos na esfera jornalística.
Formação e letramento no contexto de ensino da Pedagogia da Alternância: alguns apontamentos
Authors: Silva Cícero Da
Published: September 2019

Neste trabalho, objetiva-se compreender como o contexto de ensino da Pedagogia da Alternância (PA) e a maneira como a escrita se constitui nas práticas educativas dessa Pedagogia envolvendo a produção do gênero Caderno da Realidade (CR) podem se inscrever como práticas de letramento significativas para os estudantes inseridos no processo formativo. Considerando que o gênero é um objeto de ensino dentro do processo de letramento, a pesquisa vincula-se aos Novos Estudos do Letramento e está fundamentada na concepção de gêneros do discurso (BAKHTIN, 2006). A abordagem do objeto de estudo parte de uma revisão bibliográfica, sendo a pesquisa de natureza qualitativo-interpretativista, com procedimentos de coleta documental de dados. Os dados são compostos por textos de um exemplar do Caderno da Realidade, um instrumento didático-pedagógico das unidades de ensino que assumem a PA, produzido por um aluno do 9º ano de uma Escola Família Agrícola (EFA) localizada em uma cidade tocantinense. Analisando a construção dos CR na PA, envolvendo estudos de diferentes temas dos Planos de Estudo (PE), a pesquisa revelou a existência de práticas de letramento significativas para a formação, pois estas levam o estudante ao desenvolvimento da escrita, a produzir diversos gêneros. Ao produzir os textos que compõem o gênero em destaque, o estudante da PA vê sentido na produção de seu discurso, pois este se articula às suas práticas sociais, expressa sua identidade e realidade social.
To what extent can the chosen blood pressure measurement technique affect the outcomes of an observational survey?
Authors: Mayer Otto , Seidlerová Jitka , Mateřánková Markéta , Gelžinský Julius , Mareš Štěpán , Rychecká Martina , Svobodová Veronika , Bruthans Jan , Filipovský Jan
Published: September 2019

Aim:
We analyzed to what extent measurement protocol influenced individual blood pressure (BP) and achievement of treatment target in patients with coronary heart disease.
Methods:
In a subsample of Czech EUROASPIRE III–V survey participants (n = 913), we compared the per-protocol BP measurement (by automated oscillometric device OMRON at the beginning of survey procedure) with control auscultatory measurement (by physician during interview).
Results:
Per-protocol approach produced significantly (p < 0.0001) higher BP values (by 9/6 mmHg in median) than auscultatory measurements and led to markedly higher proportion of patients over target BP (less than 140/90 mmHg; 59.3 vs 34.9% [p < 0.0001], per-protocol vs auscultatory technique, respectively).
Conclusion:
Per-protocol oscillometric technique was not equivalent to conventional auscultatory measurement and seriously over-rated the real nonachievement of BP target in observational surveys.
Potentials Of Leading Sectors In Bangka Belitung Island Province On 2013-2017
Authors: Yulianti Atik
Published: September 2019

Decentralization and regional autonomy policies provide opportunities for development of governments and communities in the regions.  The economic and financial potential needs to be extracted and processed, so it could be a tangible output that gives an additional value to the product which lead to improving the welfare of the people in the Bangka Belitung Islands Province. Regional economics can be divided into two sectors, namely basic activities and activities rather than bases. This study uses Location Quotient method to find out and analyze the basic or superior sectors in the Bangka Belitung Islands Province. Based on the results of the research, Mining and Excavation sector, Government administration sector, Agricultural sector, Health and services sector, Real estate sector, Manufacturing industry and the big and retail trade sector; are those who have more than 1 local offering so they can be favored for the Bangka Belitung Islands Province in 2013-2017.
Kreativitas Guru Pendidikan Agama Islam dalam Pemanfaatan Media Pembelajaran dan Kemampuan Siswa dalam Memahami Materi PAI di Sekolah Dasar
Authors: Iriani Farida
Published: September 2019

This thesis research is motivated to create a learning atmosphere and learning process so that learners actively develop their potential to have the spiritual power of religion, personality, intelligence, noble character, and skill that needed him/her. Learning media as a vehicle for channeling or learning message container has a very important role in the teaching and learning process. In addition to attracting the attention of students, the media can also convey a message that is able to approach the actual object so that teachers do not need to explain elaborately about something that can not be displayed directly or concretely. The purpose of this research is to know the utilization of multimedia in improving the mastery of the material and How the results of multimedia implementation in improving the mastery of Islamic Religious Education (PAI) material in public elementary school Lambaro Angan. This test is useful for writers to add insight and experience in particular to improve the quality of teaching. For SD Negeri Lambaro Angan as a contribution of thought and for teachers to increase knowledge in the teaching and learning process. This research used the observation method. Interviews and documentation. This observation researchers use to dig the data, observe or pay attention to some things namely; the state educational institutions of Lambaro Angan State Element in the form of buildings, environmental situation, educators and teaching and learning process took place. Interview method researchers used to collect data on the use of instructional media and the results of multimedia implementation in increasing mastery of Islamic Religious Education (PAI). The data sources in this data collection are PAI Teachers, other teachers are also students of class V. With this method of documentation the author tries to collect data from documents related to media utilization in increasing the mastery of Islamic Religious Education (PAI) Negeri Lambaro Angan Aceh Besar. After the authors conduct research using some of the above methods, the authors can conclude that the use of media learning well will facilitate students to learn and more quickly learning materials.
Pendekatan Saintifik dalam Peningkatan Keaktifan Siswa pada Pembelajaran Agama Islam di SMA
Authors: Dewi Sandra
Published: September 2019

The scientific approach in teaching and learning process involves five steps: observing, questioning, gathering information, processing information, and communicating. However, most Islamic religious education (PAI) teachers still do not fully understand the implementation of the scientific approach which characterizes the 2013 curriculum. The implementation of the scientific approach in PAI lessons at SMA Negeri (public senior high school) 2 Sigli has been pursued in several steps, yet there are still some inhibiting factors that need to be improved in order to increase the students’ learning activity. The study of this thesis focused on the implementation, the steps, and the supporting and inhibiting factors of the scientific approach used to improve the students' activity in learning PAI in SMA Negeri 2 Sigli ofPidie District. The study employed a qualitative descriptive research design. Data were collected by observation, interview, and documentation. The results showed that the PAI learning has been implemented by employing the 2013 curriculum and a scientific model. The school has tried to improve the discipline and the order,optimize the learning hours, learnby scientific steps, improve the students' activity by asking them toengage in the teaching-learning processi.e.,group discussions, hands-on practice. Besides, teachers provided concrete examples related to the scientific approach model. The steps of the scientific approach werecarried out by stimulating the students on the concepts being taught, stimulating the students to ask about the concepts, facilitating the students in collecting various information related to the concepts, guiding the students to build arguments from the concepts, and guiding the students to conclude the concepts. Further, the supporting factors came from the students’ activity in learning, competent teachers, supporting facilities and infrastructure, as well as various learning methods. On the other hand, the inhibiting factors included inadequate facilities such as limited technological support tools, limited teaching time allocation, and lack of teachers including the PAI teachers adapting to the scientific approach model.
Perbandingan Hasil Belajar Biologi melalui Model Pembelajaran Student Team Achievement Division dan Jigsaw pada siswa Kelas XI SMA Negeri 1 Sangatta Utara, Kalimantan Timur
Authors: Fajrin Fajrin , Theodora Maasawet Elsje , Lumowa Sonja V.T
Published: September 2019

This research is motivated by the problem of low learning outcomes in Biology subjects due to the lack of use of varied learning models. This study aims to describe the comparison of Biology learning outcomes through STAD learning model, and Jigsaw on students conducted in April to May 2017. Data collection in this research is obtained from the test method. The data obtained from the test method were analyzed by descriptive and inferential statistical techniques (t-test), using SPSS version 23. The study showed, (1) there was comparison of learning outcomes among students who studied STAD learning model with conventional model. Based on statistical results obtained sig value. 0,000 <0.05; (2) there is comparison of learning result among students learning Jigsaw learning model with conventional model, this result is in accordance with statistical result where sig.0,000 <0,05.

Keywords: Student Team Achievement Division (STAD) Model, Jigsaw Model.

 

Abstrack.Penelitian ini dilatarbelakangi oleh masalah yaitu rendahnya hasil belajar pada mata pelajaran Biologi dikarenakan masih kurangnya penggunaan model pembelajaran yang bervariasi. Penelitian ini bertujuan untuk mendeskripsikan perbandingan hasil belajar Biologi melalui model pembelajaran STAD dan Jigsaw, pada siswa yang dilaksanakan pada Bulan April sampai Mei 2017. Pengumpulan data dalam penelitian ini didapatkan dari metode tes. Data yang didapatkan dari metode tes dianalisis  dengan teknik analisis deskriptif  dan statistif inferensial (uji-t), dengan menggunakan SPSS versi 23. Penelitian menunjukkan, (1) ada perbandingan hasil belajar antar siswa yang belajar  model pembelajaran  STAD  dengan  model konvensional. Berdasarkan hasil statistik diperoleh nilai sig. 0,000 < 0,05; (2) ada pebandingan hasil belajar antar siswa yang belajar  model pembelajaran  Jigsaw  dengan  model konvensional, hasil ini sesuai dengan hasil statistik dimana nilai sig.0,000 < 0,05.

Kata kunci: Model Student Team Achievement Division (STAD), Model Jigsaw.
Estado Laico e Religião: uma análise da atuação política do Congresso Nacional a partir de projetos de lei e discursos em plenária no período de 2013 a 2016
Authors: Verbicaro Loiane Prado , Simões Paloma Sá Souza
Published: September 2019

RESUMOO artigo tem como objetivo de estudo a presença da religiosidade nos projetos de lei e discursos em plenária proferidos por deputados federais, no período de 2013 a 2016, com intuito de evidenciar se tal influência religiosa fere a laicidade estatal. O trabalho propõe-se a explicar a importância da participação de cidadãos religiosos na vida pública, de modo que a presença deles não desconstitua a neutralidade das instituições estatais. A pesquisa é de cunho bibliográfico, utilizando como referencial teórico o autor Jürgen Habermas, e documental, a partir da análise de projetos de lei e discursos em plenária obtidos no site da Câmara dos Deputados. Propõe-se o trabalho a demonstrar a postura dual adotada pelos parlamentares quando se trata de declaração da opinião religiosa em seus discursos versus a argumentação utilizada por eles no momento de criação das legislações aplicáveis à coletividade, ressaltando o respeito ou não à laicidade do Estado.   PALAVRAS-CHAVEFilosofia Política. Laicidade. Religião. Câmara de Deputados. ABSTRACTThe article aims to study the presence of religion in bills and speeches in plenary sessions delivered by federal deputies, from 2013 to 2016, in order to highlight if such religious influence wounds state secularism. This work intends to explain the importance of religious citizens’ participation in the public life, so that their presence does not abolish the neutrality of the state institutions. The research is bibliographical, using author Jürgen Habermas’ body of work as theoretical reference, and documentary, based on the analysis of bills and speeches in plenary obtained on the Chamber of Deputies’ website. The paper proposes to demonstrate the dual position adopted by parliamentarians when it comes to the declaration of religious opinion in their speeches versus the arguments used by them at the moment of creation of statutes applicable to community, emphasizing respect towards state secularity or the lack thereof. KEYWORDSPolitical theory. Secularity. Religion. Brazilian Chamber of Deputies.
A tradição constitucionalista e sua importância para a consolidação de um regime democrático
Authors: Gonçalves Fábio Marques , Lima Danilo Pereira
Published: September 2019

RESUMOO presente artigo tem o objetivo de descrever brevemente a história do constitucionalismo moderno, passando pelos contextos históricos em que se insere essa tradição e fazendo uma análise de seu legado, construído em cada etapa de desenvolvimento do Estado moderno – Liberal, Social e Democrático. Busca-se também uma análise da realidade brasileira, fazendo-se um recorte a partir de 1988, quando surge a Constituição Democrática. Esse momento é importante para a reflexão sobre o contraste entre abertura democrática e inconstitucionalidades que se apresentam na realidade do país, devidas, em grande medida, à não superação de todos os resquícios do autoritarismo de seu passado histórico. Também se apresenta o exemplo da atuação dos meios de comunicação brasileiros, que ilustra, de forma clara, a situação de ausência de respeito à Constituição da República. Essas análises serão desenvolvidas sob o marco da Crítica Hermenêutica do Direito, de Lenio Streck. A partir desse aporte teórico, o artigo aponta para a necessidade de se fortalecer anteparos jurídicos contra qualquer manifestação personalista do poder, de modo a impedir que o direito seja solapado pela vontade dos agentes políticos. Adota-se, como técnica de pesquisa, a revisão bibliográfica e busca-se o desenvolvimento metodológico do trabalho a partir da construção de um quadro referencial teórico coerente e integrado à historicidade.PALAVRAS-CHAVEDireito Constitucional. Constitucionalismo. Estado moderno. Democracia. Crítica Hermenêutica do Direito. ABSTRACTThe present article aims to briefly describe the history of modern constitutionalism, considering the historical contexts in which this tradition is inserted and analyzing its legacy, built at each stage of development of the modern State – Liberal, Social and Democratic. An analysis of Brazilian reality is also sought, making a cut from 1988, when the Democratic Constitution arises. This moment is important for the reflection on the contrast between democratic opening and unconstitutionalities that present themselves in the reality of the country, due to, largely, not overcoming all the remnants of authoritarianism of its history. The example of the Brazilian media is also presented, which clearly illustrates the lack of respect for the Constitution of the Republic. These analyzes will be developed under the framework of the Critical Hermeneutics of Law, by Lenio Streck. Based on this theoretical contribution, the article points to the need to strengthen legal frameworks against any manifestation of personal power, to prevent Law from being undermined by the will of political agents. The bibliographical review is adopted as research technique, and the methodological development of the work is sought from the construction of a coherent theoretical framework, integrated with historicity.KEYWORDSConstitutional law. Constitutionalism. Modern State. Democracy. Crítica Hermenêutica do Direito.
Political Economy of Renewable Energy and Regional Development: Understanding Social and Economic Problems of Biodiesel Development in Indonesia
Authors: Nuva Nuva , Fauzi Akhmad , Dharmawan Arya Hadi , Kumala Putri Eka Intan
Published: September 2019

The transition of fossil fuel to non-fossil fuels (biodiesel fuel for diesel blending) has continued to evolve. The largest source of biodiesel’ raw materials in Indonesia derives from oil palm. Biodiesel development is also believed to generate benefit for society as well as for regional and national, including job creation, infrastructure improvement, revenue generation for governments and reduce national dependence on fossil fuels, and minimize adverse environmental fossil fuel impacts. However, despite its targets and strengthened by various comprehensive policies, the development of biodiesel in Indonesia also faces significant barriers. Descriptive analysis used in this study to understand the political economy of biodiesel engagement. The limited domestic market, mainly related to the issue of non-competitive prices with diesel, relatively low of oil prices, and high prices of fresh fruit bunches (FFB) are the constraints in the production of biodiesel for domestic uptake. The national political aspect related to the use of biodiesel by government parties, including non-PSOs, becomes an important issue in ensuring the sustainability of biodiesel. In addition, the issue of sustainability in the upstream (oil palm plantation) and dumping issues expressed by the EU and the US Government are also the main problems in Indonesian biodiesel export.
Patrón de susceptibilidad antibiótica de escherichia coli aislada de infecciones del tracto urinario
Authors: Baque-Pibaque Alejandro Antonio , Anchundia-Baque José Eduardo , Choez-Cañarte Mercedes Katherine
Published: September 2019

Los agentes antimicrobianos han reducido sustancialmente la amenaza de las enfermedades infecciosas. El uso de estos medicamentos, combinados con mejorías sanitarias, de vivienda y de nutrición, conjuntamente con el advenimiento de programas de inmunización, ha conllevado a un dramático descenso de muertes producto a enfermedades que antes eran intratables, y frecuentemente fatales. Se realizó un estudio descriptivo transversal con la finalidad de elaborar un Patrón de susceptibilidad antibiótica de Escherichia Coli aisladas de infecciones del tracto urinario en el laboratorio Clínico “Santa Lucía María”, Santa Ana, Manabí, durante el período comprendido entre el 1 de enero al 31 de diciembre de 2015.la población de estudio fueron los 224 urocultivos donde se aisló Escherichia Coli. Los resultados arrojaron que la mayor incidencia de infecciones del tracto urinario confirmadas por urocultivos tuvo lugar en las mujeres de 12 a 27 años y que la nitrofurantoina presento una alta sensibilidad para E. Coli aisladas de ITU.
PENGARUH MODEL ATI BERBANTUAN MEDIA AUDIO VISUAL TERHADAP HASIL BELAJAR IPA SISWA KELAS V SD
Authors: Ariasa Komang Merdana
Published: September 2019

This study used quasi experiment research through post test which only used control group design. This study tried to experiment Aptitude Treatment Interaction (ATI) model assisted audio visual media aimed to know the effect on science learning outcomes in grade V elementary students in Group IV Cempaka Putih Kecamatan Kubutambahan. The population of this study were the entire students of grade V in group IV Cempaka Putih, which amount to 168 students. The sample of this research were class V SDN 2 and 3 Bulian with the number of each students were 25 and 2, which was determined by random sampling technique. The data were analyzed by descriptive statistic and Independent Sample t-test. The results showed that the value of t count of 2.025 and ttab of 2.00. It meant that there was a significant effect of science learning outcomes between groups of students who were taught by ATI model assisted audio visual media and groups of students who were taught by non-ATI assisted by audio visual media.
PENGARUH MODEL PEMBELAJARAN INKUIRI TERBIMBING BERBANTUAN MEDIA KONKRET TERHADAP KOMPETENSI PENGETAHUAN IPA SISWA KELAS IV SD GUGUS DEWI SARTIKA DENPASAR TIMUR TAHUN PELAJARAN 2017/2018
Authors: Sari Kadek Diah
Published: September 2019

The purpose of this study was to know the significant different in science knowledge between the group of students who were taught through Guided Inquiry Learning Model assissted by concrete media and the group of students who were taught through conventional learning model at grade IV students of SD Gugus Dewi Sartika Denpasar Timur in academic year 2017/2018.  The population of this research was all fourth grade students of SD Gugus Dewi Sartika Denpasar Timur in academic year 2017/2018. The sampling was conducted by random sampling technique by randomizing class. The sample of this research was IV B of SD N 10 as experimental group and IV B of SD N 3 Kesiman as control group with the total number of experimental group was 40 students and the contol group was 41 students. The data collected was the data of the competency of science knowledge and analyzed by t-test. After being analyzed by t-test, obtained tcount = 2,372 at significance level 5% ( = 0,05) with dk = 79 and ttable (a = 0,05) = 2.000. Based on the test value tcount = 2.372 > ttable (a = 0,05) = 2.000. The results showed that experimental gained more score in compared to control group with mean of = 0,41> = 0,31, it can be concluded that there is an effect by implementing Guided Inquiry Learning Model toward science knowledge competence. Thus, there is a significant difference between the science knowledge of the group which were taught through Guided Inquiry Learning Model assissted by Concrete Media and the group of students who were taught through conventional learning in IV grade students of SD Gugus Dewi Sartika East Denpasar in academic year 2017/2018.
PENGARUH MODEL PEMBELAJARAN DISCOVERY LEARNING BERBASIS PENILAIAN PORTOFOLIO TERHADAP KOMPETENSI PENGETAHUAN MATEMATIKA SISWA KELAS IV
Authors: Christianti Md Rai Advina
Published: September 2019

This study is aim to determine the effect of discovery learning model besed on portofolio of mathematies knowledge competencies of IV grade students of elementary school Gugus II Kuta Utara academic year 2017/2018. This research is an quasi experiment design with Nonequvalent Control Group Design. Population in this research were all students of IV elementary school Gugus II Kuta Utara academic year 2017/2018 as many as 277 students. The sample of this research is the IV grade student of elementary school No. 3 canggu as experimental class and IVC grade student of elementary school No. 1 Tububeneng as control class with the total of each group as much as 30 students after equalized by matching technique. The method of data collection in this research is test method, with the usual double choice test amount of 30 items that have been validity. The data analysis using t-test shows that there is were significant differences of students mathematics knowledge competency which is learned by using discovery learning model besed on portofolio and students who ware taught by using conventional learning in IV grade students of elementary school Gugus II Kuta Utara academic year 2017/2018. This is evidensed by the (thitung = 2,683 > ttabel = 2,021) at the significant of 5% with dk n1+n2-2 (30+30-2=56) and the average competency value of mathematics knowledge of students experimental group 73,50 and the average of competence value of mathematic knowledge of student control group 64,40. Thus, it can be concluded that the application of discovery learning model besed portofolio influence the knowledge competence of mathematics IV grade in elementary school Gugus II Kuta Utara academic year 2017/2018
HUBUNGAN ANTARA KEMAMPUAN LITERASI DENGAN KOMPETENSI INTI PENGETAHUAN BAHASA INDONESIA SISWA KELAS V SD GUGUS LETKOL WISNU DENPASAR UTARA TAHUN PELAJARAN 2017/2018
Authors: Yulina Sari Ni Ayu Made
Published: September 2019

This study aimed to determine the significant relationship between the literacy skills with the core competency of knowledge of Indonesian language students of grade V SD Gugus Letkol Wisnu, North Denpasar, in the Lesson Year 2017/2018. This research is ex post facto research with correlation type. The population of this study is a class V student residing in SD Gugus Letkol Wisnu, North Denpasar Lesson Year 2017/2018 which has a population of 340 people. Determination of the sample used proportional random sampling technique with significant level 5% and obtained the number of samples from the population is 172 people. The data were obtained through the multiple-choice objective test of the literacy skills and the document recording of the core competency of knowledge of Indonesian language student. As the test is a normality test data distribution. After all prerequisite tests are met, the statistical analysis used in this next study is hypothesis test using product moment correlation analysis. Based on result of analysis then  = 0,227. At the significant level of 5% with n = 172, then obtained  = 0.148. Because  >  =  0.227 >  0.148 it can be interpreted that H₀ which reads there is not significant relationship between literacy skills with the core competency of knowledge of  Indonesian language students of grade V SD Gugus Letkol Wisnu, North Denpasar, in the Lesson Year 2017/2018 is rejected and  accepted. So it can be concluded that there is a significant relationship between literacy skills with the core competency of knowledge of Indonesian language students of grade V SD Gugus Letkol Wisnu, North Denpasar, in the Lesson Year 2017/2018, with a positive correlation direction, meaning the higher literacy skills then the higher the core competency of knowledge of Indonesian language students. Keywords : Literacy skills, the core competency of knowledge, Indonesian
PROFESIONALISME GURU BERSERTIFIKASI DI SD NEGERI SIWALAN DAN SD NEGERI PETERONGAN SEMARANG
Authors: Aiin Ufii Khoirul , Muhajir Muhajir , Agustini Ferina
Published: September 2019

Penelitian ini bertujuan untuk mengetahui apakah guru bersertifikasi di SD Negeri Siwalan dan SD Negeri Peterongan Semarang sudah profesional dalam pembelajaran. Jenis metode penelitian ini kualitatif. Populasi penelitian ini adalah guru bersertifikasi di SD Negeri Siwalan dan SD Negeri Peterongan Semarag. Sampel penelitian yang diambil adalah lima guru bersertifikasi di SD Negeri Siwalan dan SD Negeri Peterongan Semarang. Teknik dalam penelitian ini diperoleh melalui penilaian angket, wawancara dan dokumentasi. Hasil analisis angket profesionalisme guru bersertifikasi menunjukkan bahwa kompetensi pedagogik dengan skor (2,845), kompetensi kepribadian dengan skor (3), kompetensi sosial dengan skor (3), dan kompetensi profesional dengan skor (2,89). Dengan adanya rata-rata skor tersebut dapat disimpulkan bahwa guru bersertifikasi di SD Negeri Siwalan dan SD Negeri Peterongan Semarang sudah Kompeten/ Profesional. Kata-kata kunci : Guru, Profesionalisme, Sertifikasi
PENGARUH INTENSITAS LAYANAN BIMBINGAN KARIR TERHADAP KEMATANGAN KARIR
Authors: Dewi Arintya Kusuma , - Setyorini
Published: September 2019

Penelitian ini bertujuan untuk mengetahui pengaruh intensitas layanan bimbingan karir terhadap kematangan karir siswa kelas XI di SMK Kristen (BM) Salatiga. Berdasarkan tujuannya, pendekatan penelitian ini digolongkan penelitian ex post facto, sementara dari jenis datanya, penelitian ini dikategorikan penelitian kuantitatif. Jumlah populasi dan sampel penelitian ini adalah 85 orang kelas XI SMK Kristen (BM) Salatiga. Jenis data yang digunakan adalah data primer, teknik pengambilan data menggunakan metode angket dimana peneliti menggunakan teori dari Super (dalam Setyorini, 2012) untuk variabel kematangan karir dan teori dari Winkel (dalam Andini, 2008) untuk variabel intensitas bimbingan karir. Alat analisis yang digunakan adalah regresi linier sederhana. Hasil penelitian menunjukkan bahwa “Ada pengaruh yang signifikan Intensitas Bimbingan Karir terhadap Kematangan Karir Siswa Kelas XI SMK Kristen (BM) Salatiga”, dibuktikan nilai signifikansi hasil penelitian (0,000) < 0,05, dengan R Square sebesar 0,279, artinya bahwa sumbangan relatif intensitas bimbingan karir terhadap kematangan karir sebesar 29,90%, sisanya oleh variabel lain. Kata-kata kunci : Intensitas Bimbingan Karir, Kematangan Karir Siswa, Siswa Kelas XI SMK Kristen (BM) Salatiga, Regresi Liner Sederhana
HUBUNGAN ANTARA TIPE KEPEMIMPINAN KEPALA SEKOLAH DENGAN KINERJA GURU BIMBINGAN DAN KONSELING
Authors: Lapura Devince Boba
Published: September 2019

Penelitian ini bertujuan untuk mengetahui signifikansi hubungan antara tipe kepemimpinan kepala sekolah dengan kinerja guru BK SMP Negeri di Kota Salatiga. Subjek pada penelitian ini adalah seluruh guru BK SMP Negeri di Kota Salatiga  berjumlah 32 orang yang berasal dari 10 sekolah. Teknik pengambilan sampel yang digunakan adalah Total Sampling. Teknik analisis data menggunakan koefisien contingency dengan bantuan SPSS Statistics 22. Instrumen yang digunakan dalam penelitian ini berupa angket. Untuk mengetahui tipe kepemimpinan kepala sekolah penulis menggunakan teori Wahab (2008) dan untuk mengetahui kinerja guru BK berdasarkan Peraturan Menteri Pendidikan Nasional Nomor 27 Tahun 2008 tentang Standar Kualifikasi Akademik dan Kompetensi Konselor. Berdasarkan hasil analisis koefisien contingency diperoleh nilai koefisien antara tipe kepemimpinan kepala sekolah dengan kinerja guru BK sebesar 0,553 dengan signifikansi 0,000 < 0,05. Dengan demikian dapat disimpulkan bahwa ada hubungan yang signifikan antara tipe kepemimpinan kepala sekolah dengan kinerja guru BK SMP Negeri di Kota Salatiga. Kata-kata kunci : Tipe Kepemimpinan, Kinerja Guru BK
PENGARUH MEDIA KOMIK PADA MODEL PEMBELAJARAN TWO STAY-TWO STRAY TERHADAP HASIL BELAJAR IPS
Authors: Mardiantanto Resa , Purnamasari Iin , Arifin Zaenal
Published: September 2019

Pengaruh Media Komik Pada Pembelajaran Model Two Stay-Two StrayTerhadap Hasil Belajar IPS Kelas V SDN 04 Gabus Pati. Tujuan dalam penelitian ini adalah untuk mengetahui pengaruh media komik dalam meningkatkan hasil belajar siswa pada materi Persiapan Memproklamasikan Indonesia. Jenis penelitian ini adalah kuantitatif menggunakan Pre Experimental Design yang digunakan adalah One GroupPretest-Posttest Design. Populasi penelitian adalah seluruh siswa SDN 04 Gabus tahun pelajaran 2018/2019. Sampel yang diambil adalah 25 siswa kelas V. Data dalam penelitian ini diperoleh melalui observasi, wawancara, tes, dan dokumentasi.. Kata-kata kunci : Pengaruh, media komik, ts-ts, IPS, hasil belajar
HUBUNGAN KOMUNIKASI INTERPERSONAL DENGAN PERILAKU BULLYING SISWA
Authors: Wicaksana Nicolas Adi , Setyorini Setyorini
Published: September 2019

Jenis penelitian ini adalah penelitian korelasional. Penelitian ini bertujuan untuk mengetahui signifikansi hubungan antara komunikasi interpersonal dengan perilaku bullying pada Siswa Kelas XII RPL SMK  Negeri 1 Tengaran. Subjek penelitian yang diambil adalah siswa kelas XII RPL yang berjumlah 90 siswa. Teknik pengambilan subjek menggunakan total sampling . Alat ukur yang digunakan dalam penelitian ini adalah mengadaptasi dari Nunung (2009) berdasarkan teori Olweus,1993 (dalam SEJIWA, 2008) serta skala komunikasi Interpersonal yang diadaptasi berdasarkan teori DeVito (2011). Teknik analisis data yang digunakan adalah Kendall’s tau b dengan bantuan program SPSS for Window Release 20.0. Hasil analisis korelasi menunjukan bahwa antara komunikasi interpersonal dengan perilaku bullying terdapat hubungan yang negatif dan signifikan. Hal ini ditunjukkan dengan nilai rxy = -0,162* dan nilai p = 0,036 < 0,050.  Kata Kunci : Komunikasi Interpersonal, Perilaku Bullying.
Kefektifan Model Student Teams Achivement Divison (STAD) Terhadap Keterampilan Berbicara
Authors: Panur Permana Bagas , Nashir Tsalatsa Ahmad , Asri Untari Mei Fita
Published: September 2019

Keefektifan Model Student Teams Achivement Division (STAD) Terhadap keterampilan Berbicara Pada Kelas V SDN Kaliwiru Semarang. Penelitian ini bertujuan untuk mengetahui keefektifan Model Teams Achivement Division (STAD). Jenis penelitian ini adalah penelitian kuantitatif dengan bentuk desain yang digunakan dalam penelitian ini adalah One-Grup Pretest-posttest design. Berdasarkan hasil analisis yang telah dilakukan rata-rata skor pretest pada mencapai 53 dan posttest mencapai 81 Berdasarkan dari uji t pada diperoleh harga thitung > ttabel yaitu 14.209 > 1,684. Dengan demikian Ho ditolak dan Ha diterima. Dapat disimpulkan bahwa Model Student Teams Achievement Division (STAD) efektif terhadap keterampilan berbicara siswa kelas V SD Negeri kaliwiru Semarang Tahun ajaran 2019. Kata kunci: Keefektifan, Model pembelajaran Student Team Achievement (STAD), keterampilan berbicara
Pengaruh Model Pembelajaran Think Pair Share Terhadap Keaktifan dan Hasil Belajar IPA
Authors: Fitriati Nurjannah Putri
Published: September 2019

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran think pair share terhadap keaktifan dan hasil belajar IPA Kelas III SDN Kedungrejo 02 Tunjungan Blora. Menggunakan metode Pre-Eksperimental Design model One-Group Pretest-Posttest Design. Hasil posttest keatktifan memiliki rata-rata lebih tinggi yaitu 79,45 serta pretest 71,80. Berdasarkan perhitungan hipotesis menggunakan uji t didapatkan   12,296 dengan  2,06 disimpulkan thitung>ttabel H0 ditolak. Sedangkan analisis data hasil belajar siswa diperoleh rata-rata pretest sebesar 37,60 dan posttest 77,40. Data tersebut didukung oleh analisis uji-t didapatkan thitung 36,232 dengan  2,06 disimpulkan thitung>ttabel H0 ditolak Maka dapat disimpulkan bahwa ada pengaruh signifikan model pembelajaran think pair share terhadap keaktifan dan hasil belajar IPA kelas III. Kata kunci : Think Pair Share, Hasil belajar
ANALISIS NILAI-NILAI KARAKTER DALAM PEMBELAJARAN EKSTRAKURIKULER DRUM BAND
Authors: Khoiriyah Meiyani Lutfil , Tika Damayani Aries , . Rofian
Published: September 2019

Jenis penelitian ini adalah deskriptif kualitatif. Penelitian ini menggunakan metode pengumpulan data berupa observasi, wawancara, dan dokumentasi. Hasil analisis data bahwa pelaksanaan kegiatan ekstrakurikuler drum band dilaksanakan setiap hari Sabtu. Siswa yang mengikuti ekstrakurikuler drum band berjumlah 23 siswa. Nilai-nilai karakter yang diteliti diantaranya, sikap disiplin, kerja keras, mandiri, demokratis, bersahabat/komunikatif, cinta damai, peduli sosial, peduli lingkungan dan tanggung jawab. Berdasarkan hasil wawancara dan observasi yang dilakukan menunjukkan bahwa sikap siswa sudah  sesuai dengan nilai-nilai karakter. Saran yang dapat disampaikan peneliti untuk sekolah telah menjalankan nilai-nilai karakter dalam pembelajaran ekstrakurikuler drum band SD Al Huda Semarang, hendaknya keadaan seperti ini dipertahankan bahkan ditingkatkan. Kata kunci : nilai karakter, pembelajaran ekstrakurikuler drum band
META-ANALISIS EFEKTIVITAS PENGGUNAAN MEDIA ANIMASI DALAM MENINGKATKAN HASIL BELAJAR IPA
Authors: Khomaidah Siti , Harjono Nyoto
Published: September 2019

Tujuan penelitian ini untuk menganalisis penggunaan media animasi terhadap hasil belajar IPA siswa Sekolah Dasar. Dalam penelitian ini metode yang digunakan berupa meta analisis dengan cara menganalisis data-data tentang pengaruh media animasi terhadap hasil belajar IPA siswa Sekolah Dasar. Penelitian ini di awali dengan merumuskan topik penelitian, menelusuri hasil penelitian yang relevan untuk di analisis. Data dikumpulkan dengan menelusuri jurnal online dan skripsi. Data dianalisis dengan menggunakan analisis diskriptif kuantitatif. Berdasarkan hasil analisis penggunaan media animasi pada pembelajaran IPA di Sekolah Dasar mampu meningkatkan hasil belajar IPA siswa Sekolah Dasar mulai dari yang terendah 3.93% sampai yang tertinggi 98.76% dengan rata-rata 27.009%. Kata Kunci: Meta analisis, hasil belajar, media animasi.