bluuebunny/crossref_metadata_2025 huggingface dataset:
Amlodipine inhibits the proliferation and migration of esophageal carcinoma cells through the induction of endoplasmic reticulum stress
Authors: Chen Yan-Min , Yang Wen-Qian , Gu Cheng-Wei , Fan Ying-Ying , Liu Yu-Zhen , Zhao Bao-Sheng
Published: January 2024

BACKGROUND

L-type calcium channels are the only protein channels sensitive to calcium channel blockers, and are expressed in various cancer types. The Cancer Genome Atlas database shows that the mRNA levels of multiple L-type calcium channel subunits in esophageal squamous cell carcinoma tumor tissue are significantly higher than those in normal esophageal epithelial tissue. Therefore, we hypothesized that amlodipine, a long-acting dihydropyridine L-type calcium channel blocker, may inhibit the occurrence and development of esophageal cancer (EC).

AIM

To investigate the inhibitory effects of amlodipine on EC through endoplasmic reticulum (ER) stress.

METHODS

Cav1.3 protein expression levels in 50 pairs of EC tissues and corresponding paracancerous tissues were examined. Subsequently, the inhibitory effects of amlodipine on proliferation and migration of EC cells in vitro were detected using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide and Transwell assays. In vivo experiments were performed using murine xenograft model. To elucidate the underlying mechanisms, in vitro cell studies were performed to confirm that ER stress plays a role in inhibition proliferation and migration of EC cells treated with amlodipine.

RESULTS

The expression level of Cav1.3 in esophageal carcinoma was 1.6 times higher than that in paracancerous tissues. Amlodipine treatment decreased the viability of esophageal carcinoma cells in a dose- and time-dependent manner. In vivo animal experiments also clearly indicated that amlodipine inhibited the growth of EC tumors in mice. Additionally, amlodipine reduces the migration of tumor cells by inhibiting epithelial-mesenchymal transition (EMT). Mechanistic studies have demonstrated that amlodipine induces ER stress-mediated apoptosis and suppresses EMT. Moreover, amlodipine-induced autophagy was characterized by an increase in autophagy lysosomes and the accumulation of light chain 3B protein. The combination of amlodipine with the ER stress inhibitor 4-phenylbutyric acid further confirmed the role of the ER stress response in amlodipine-induced apoptosis, EMT, and autophagy. Furthermore, blocking autophagy increases the ratio of apoptosis and migration.

CONCLUSION

Collectively, we demonstrate for the first time that amlodipine promotes apoptosis, induces autophagy, and inhibits migration through ER stress, thereby exerting anti-tumor effects in EC.
Current status of magnetic resonance imaging radiomics in hepatocellular carcinoma: A quantitative review with Radiomics Quality Score
Authors: Brancato Valentina , Cerrone Marco , Garbino Nunzia , Salvatore Marco , Cavaliere Carlo
Published: January 2024

BACKGROUND

Radiomics is a promising tool that may increase the value of magnetic resonance imaging (MRI) for different tasks related to the management of patients with hepatocellular carcinoma (HCC). However, its implementation in clinical practice is still far, with many issues related to the methodological quality of radiomic studies.

AIM

To systematically review the current status of MRI radiomic studies concerning HCC using the Radiomics Quality Score (RQS).

METHODS

A systematic literature search of PubMed, Google Scholar, and Web of Science databases was performed to identify original articles focusing on the use of MRI radiomics for HCC management published between 2017 and 2023. The methodological quality of radiomic studies was assessed using the RQS tool. Spearman’s correlation (ρ) analysis was performed to explore if RQS was correlated with journal metrics and characteristics of the studies. The level of statistical signi-ficance was set at P < 0.05.

RESULTS

One hundred and twenty-seven articles were included, of which 43 focused on HCC prognosis, 39 on prediction of pathological findings, 16 on prediction of the expression of molecular markers outcomes, 18 had a diagnostic purpose, and 11 had multiple purposes. The mean RQS was 8 ± 6.22, and the corresponding percentage was 24.15% ± 15.25% (ranging from 0.0% to 58.33%). RQS was positively correlated with journal impact factor (IF; ρ = 0.36, P = 2.98 × 10-5), 5-years IF (ρ = 0.33, P = 1.56 × 10-4), number of patients included in the study (ρ = 0.51, P < 9.37 × 10-10) and number of radiomics features extracted in the study (ρ = 0.59, P < 4.59 × 10-13), and time of publication (ρ = -0.23, P < 0.0072).

CONCLUSION

Although MRI radiomics in HCC represents a promising tool to develop adequate personalized treatment as a noninvasive approach in HCC patients, our study revealed that studies in this field still lack the quality required to allow its introduction into clinical practice.
Ant colony optimization for parallel test assembly
Authors: Zimny Luc , Schroeders Ulrich , Wilhelm Oliver
Published: January 2024

Ant colony optimization (ACO) algorithms have previously been used to compile single short scales of psychological constructs. In the present article, we showcase the versatility of the ACO to construct multiple parallel short scales that adhere to several competing and interacting criteria simultaneously. Based on an initial pool of 120 knowledge items, we assembled three 12-item tests that (a) adequately cover the construct at the domain level, (b) follow a unidimensional measurement model, (c) allow reliable and (d) precise measurement of factual knowledge, and (e) are gender-fair. Moreover, we aligned the test characteristic and test information functions of the three tests to establish the equivalence of the tests. We cross-validated the assembled short scales and investigated their association with the full scale and covariates that were not included in the optimization procedure. Finally, we discuss potential extensions to metaheuristic test assembly and the equivalence of parallel knowledge tests in general.
Inscripción provisional de órdenes proferidas por autoridad competente en el registro público de Panamá
Authors: Olmedo Gisel
Published: January 2024

Las inscripciones provisionales relacionadas a bienes y actos sujetos a registro, tienen su origen en procesos judiciales. Estos procesos tienen por finalidad, el reconocimiento y ejercicio de un derecho sobre los referidos bienes. Los documentos u órdenes judiciales que constituyen materia de registro de forma general son: la demanda, secuestro, embargo y las medidas innominadas o atípicas, así como las órdenes proferidas por el Tribunal de Cuentas.
Construyendo un verdadero liderazgo educativo universitario
Authors: Rivera Corredor David Alberto , Méndez Sosa Carlos Andrés
Published: January 2024

Las universidades en la sociedad siempre han sido altamente relevantes, estas instituciones constituyen un protagonismo determinante en el desarrollo y la economía de todo país, encargándose en gran medida del progreso científico y tecnológico, del desarrollo investigativo y claramente de la formación de futuros profesionales competentes y aptos a encarar todos los desafíos y situaciones cambiantes de la sociedad. Las propiedades del liderazgo, pensando en una la responsabilidad del liderazgo educativo, no solo recae en la gerencia y/o en las personas que dirigen estas instituciones. Si bien el aseguramiento de la calidad ayuda a las instituciones a adquirir las condiciones necesarias para mejorar los procesos y aumentar la calidad de los resultados, conseguir renovaciones de registros calificados, etc., el alcance del liderazgo educativo no puede verse limitado por meras certificaciones o acreditaciones ni verse patrocinado únicamente por un puñado de directivos. De modo que, todos los miembros de una comunidad universitaria tienen un rol significativo en el liderazgo educativo. Es necesario hacer especial hincapié en papel del profesorado pues estas son las personas que finalmente tienen un contacto directo y constante con el estudiantado y logran forjar comunidades de aprendizaje. El objetivo de este ensayo consiste en demostrar que el liderazgo educativo universitario debe estar basado en el establecimiento de una cultura de calidad que abogue por la participación de toda la comunidad educativa y beneficie la formación personal, laboral, social y profesional de estos mismos.
Pensamiento computacional en la política pública educativa de Colombia
Authors: Felizzola Medina Luz Darys , Licona Suarez Levinton José , Vásquez Acevedo Hanine María
Published: January 2024

La era de la Revolución Industrial 4.0, destacada por la proliferación y sinergia de la información como avance tecnológico propicia para el desarrollo de competencias del recurso humano que requieren las organizaciones a nivel mundial, devela la necesidad de potenciar la competencia del Pensamiento Computacional desde los espacios educativos, puesto que su esencia es la resolución de problemas, fundamentada en procesos de pensamiento y estrategias en el campo de la tecnología y computación (Zapata-Ros, 2018). De allí que, el presente artículo tiene como propósito analizar la política pública colombiana para el desarrollo del Pensamiento Computacional  en la educación básica y media en Colombia, por ello se realiza un estudio de carácter cualitativo, hermenéutico, basado en el corpus de análisis documental de contenido e interpretación profunda de las  “Orientaciones Curriculares para el Área de Tecnología e Informática en la Educación  Básica y  Media”, y las “Orientaciones para la Articulación del Pensamiento Computacional con el Plan de Estudios de Matemáticas”, emitidas por el Ministerio de Educación Nacional (MEN) y Ministerio de tecnologías de la información y las comunicaciones (MINTIC), en convenio con el  Bristisch Council. Para el mismo, se asume como categoría principal el Pensamiento Computacional; y como subcategorías: la alfabetización digital y la resolución de problemas. Vale la pena destacar que en este estudio se evidencia la complementariedad entre los documentos, la resolución de problemas es el eje de ambos, uno se enfoca en alfabetización digital y el otro en Pensamiento Computacional.
Recorrido didáctico: Una aproximación teórico práctica en procesos educativos
Authors: Salazar Vargas Jorge Eduardo
Published: January 2024

En la actualidad la didáctica sigue teniendo un papel determinante dentro de los procesos de enseñanza y aprendizaje, asumiendo un rol que ayuda a fortalecer, dinamizar, flexibilizar y transformar los procesos vivenciados en el aula de clase y fuera de ella, ya que, la aplicación y conceptualización de esta, se encuentra en un proceso de constante transformación para estar a la par de las evoluciones sociales. Es por esto que, el siguiente artículo es un documento de reflexión no derivado de investigación, en donde, se realizó una revisión bibliográfica teniendo presente los referentes teóricos y prácticos vigentes disponibles en bases de datos encontrados en la red con relación a la didáctica, sus procesos de transformación, evolución y modelos didácticos.
Competencias emocionales de los docentes y su relación con la educación emocional de los estudiantes
Authors: Acosta Faneite Savier Fernando
Published: January 2024

Las competencias emocionales de los profesores son esenciales para la creación de un entorno de apoyo, que fomente las habilidades emocionales de los alumnos y los prepare para una vida emocionalmente equilibrada y exitosa. El objetivo del estudio consistió en establecer la relación entre las competencias emocionales de los docentes y la educación emocional de los estudiantes. Se empleó un enfoque cuantitativo, con nivel descriptivo correlacional, a una muestra de 26 profesores y 26 alumnos de la Escuela de Educación de la Universidad del Zulia. Se utilizó un muestreo intencional, como técnica la encuesta y los instrumentos estandarizados Bar-On Emotional Quotient Inventory (EQ-i) y el Cuestionario de Desarrollo Emocional de Adultos (QDE-A). Los resultados indican una correlación significativa (p < 0.000) y alta correlación positiva (r = 0.798) entre las competencias emocionales de los docentes y la educación emocional de los alumnos. Esto sugiere que profesores con fuertes habilidades emocionales son más capaces de educar emocionalmente a los alumnos de manera consistente. Se concluye que los educadores con competencias emocionales sólidas desempeñan un papel esencial en la formación holística de los estudiantes, ayudándoles a desarrollar competencia emocional beneficiosa para que la apliquen a lo largo de sus vidas.
Neurofisiología de la oclusión: Disfunción de la articulación temporomandibular en adultos que visitan al odontólogo
Authors: Rangel Castro Michelle del Carmen
Published: January 2024

El sistema estomatognático no es más que todas las partes que utilizamos de la cara, cabeza y cuello para realizar funciones vitales como las de alimentación, fonación y estética. Este sistema se le conoce como el Aparato Masticador o Sistema Gnático y constituye la base de la definición de los conceptos de normalidad, patogénesis, tratamiento y prevención de las enfermedades buco dentales. Los elementos constitutivos del sistema Gnático son: los dientes y sus estructuras de soporte; maxilares y algunos huesos del cráneo y la cara; músculos de la cabeza y cuello; articulaciones témpormandibulares (ATM) y occipito-atloidea; sistema vascular nervioso y linfático que corresponden a los tejidos antes mencionados, Hoffman Ramfjord & Ash, 1972; Vartam 19741. Todos los elementos mencionados anteriormente son indispensables y se relacionan íntimamente con el resto del organismo y, por ende, con el estado de salud en general de un individuo.  Sin embargo, debemos resaltar al Sistema Muscular de la cabeza y cuello, pues, es en ese punto en donde se pueden encontrar la mayoría de las afectaciones o sintomatologías de los pacientes con mala mordida (oclusión), que conllevan a una disfunción de la articulación temporomandibular. La relación armoniosa y la estabilidad de los componentes musculares van a depender de la relación que existe entre la ATM y sus movimientos, con los dientes y su morfología oclusal. En el presente artículo intentaremos resumir como desde el punto de vista de la anatomía descriptiva, no se habían tomado en cuenta para determinar patología y estados de enfermedades comunes como los dolores de cabeza, de oído, del cuello, del hombro y de la parte alta de la espalda.
Prevención de patologías y relevancia de las estructuras anatómicas en la ejecución de los instrumentos musicales, caso: Fundación de música y arte de Panamá
Authors: Suncín Miguel Ángel
Published: January 2024

Muchas estructuras anatómicas intervienen durante la interpretación musical. Desde la respiración, cuya fisiología involucra estructuras anatómicas como los pulmones, junto a los músculos respiratorios; las estructuras maxilofaciales como la articulación temporomandibular, en conjunto con los músculos masticadores, la lengua y el orbicular de la boca; los miembros superiores, sus articulaciones y musculatura,  y, por último, la columna vertebral y los músculos del dorso.  En conjunto, estas estructuras son el engranaje perfecto que permite la interpretación musical; sin embargo, representan a su vez el blanco para ser víctimas  de patologías asociadas al uso excesivo de cualquiera de ellas. Fisioterapéuticamente, conocer estas patologías nos permitirá elaborar protocolos de prevención y atención de las lesiones, de rehabilitación y mantenimiento del estado de salud de las estructuras involucradas.  Esta investigación se encuentra actualmente en periodo de ejecución, sin embargo, después de la revisión literaria, y una observación grosso modo de los músicos al momento de la interpretación, podemos decir que sí hay actividad de los músculos respiratorios, el diafragma, músculo orbicular de la boca, articulación temporomandibular,  articulaciones y músculos del miembro superior y de los músculos del dorso, y  también de la columna vertebral. En conclusión, todas estas estructuras están expuestas a  sufrir lesiones por fatiga o sobre carga muscular.
Causas y efectos de la dermatitis por contacto a la exposición del cemento en trabajadores de la construcción en la barriada sueños de Santiago, Santiago-Veraguas
Authors: Jiménez Yamileth A.
Published: January 2024

La Salud y Seguridad Ocupacional tienen como propósito primordial el velar por la seguridad de los trabajadores en el área laboral y de esta manera minimizar los problemas que pudieran presentarse. Uno de los problemas más comunes dentro del sector de la construcción es el relacionado a la aparición de enfermedades, como la dermatitis, producto del contacto con agentes exógenos como es el caso del cemento. Este artículo se enfoca en determinar las causas y efectos de la dermatitis por contacto a la exposición del cemento en trabajadores de la construcción del proyecto Sueños de Santiago, La Reserva, cuyos objetivos establecidos fueron identificar la relación que existe entre la exposición al cemento en los trabajadores del sector de la construcción y la aparición de dermatitis por contacto y determinar los factores que intervienen en la prevalencia de la dermatitis por contacto por la exposición al cemento, la metodología de investigación fue descriptiva ya que su finalidad es el análisis de la situación presentada en la empresa; basado en el análisis de la información y en estudios realizados sobre la dermatitis por contacto con cemento en los trabajadores de la construcción; los resultados obtenidos fueron que un 5% tiene menos de 25 años, el 20% tiene entre 25 y 30 años, un 40% está entre los 30 y 40 años y hay un 35% con más de 40 años, en cuánto a los años de trabajo en el sector construcción un 5% tiene menos de 5 años, un 10% entre 5 y 10 años, un 30% entre 10 y 15 años, 25% entre 15 y 20 años y el 30% restante más de 20 años, en cuanto a si ha presentado problemas de salud en los últimos años el 60% dice que sí los ha presentado, hay un 40% que dice que no, en relación con el uso de cemento, hay un 80% de los encuestados que lo usan de manera frecuente, solo un 20% de los trabajadores no tienen contacto frecuente con este agente, el 90% de los trabajadores encuestados han sufrido problemas de la piel en algún momento, un 10% dice no haber presentado problemas, seguidamente un 90% manifestó que es importante establecer un programa de prevención para disminuir los problemas de salud, posteriormente el 100% de los trabajadores aseguran que es importante realizar cambios para la protección al momento de realizar sus actividades, los resultados se obtuvieron con la aplicación del análisis de los datos con el software SPSS STATISTIC 23 para dar decisión de rechazo o aceptación de las hipótesis; se concluyó en base a los resultados estadísticos rechazar la hipótesis nula y determinar que existe una marcada relación entre la dermatitis por contacto y la exposición al cemento y demostró una relación estadísticamente positiva y significativa.
A Study of the utilization and problems of artificial intelligence(AI) technology in tax operations
Authors:   KOREAN SOCIETY OF TAX LAW, Lee Chang Kyu
Published: January 2024

Information and communication technology (ICT) is being utilized in various places, mainly in the Internet of Things (hereinafter referred to as IoT), depending on the degree of its development. Among these new technologies, artificial intelligence (AI) technology is progressing rapidly, and mobile-based translation apps and Internet recommendation functions are already in use in our surroundings. In line with this, tax authorities are moving tax procedures online through the enactment of laws and implementation of systems related to the construction of tax administration using ICT.
It is not only silk tax accountants who are being forced to innovate due to the development of AI technology characterized by advanced information processing, but also professionals such as lawyers, legal consultants, and administrative consultants should establish their own duties. . In particular, since the tax field is related to a wide range of fields including individuals and companies, there is a need to seek bolder cooperation. Along with this, there is a need to actively utilize AI technology to improve operational efficiency. In the future, rather than AI taking away human jobs, I think AI will be left with simple tasks that it can do well, and tax accountants will concentrate on tasks that require advanced skills that only humans can do.
Article 1 of the “Tax Judiciary” clearly states that the purpose is to establish a tax consultant system and ensure the smooth implementation of tax administration and the proper fulfillment of tax obligations. As long as there is a self-assessment tax system, it is important for our tax accountants to raise the public's tax awareness and encourage taxpayers to declare and pay their taxes. In addition, tax accountants, acting as taxpayers' agents, must deal with complex tax systems and ensure that appropriate tax payments are made even in cases where opinions differ on non-obvious issues. It is expected that some of the tax services that fall under the category of ancillary services will disappear. In the future, tax representation, tax document preparation, tax consultation, and the preparation of tax documents, which are the exclusive services of tax accountants, may no longer be necessary for tax returns that do not require complex tax procedures. Tax accountants, who perform tax-related representation and other activities in response to taxpayers' requests, will have to understand the demands of taxpayers over time and assume a new social role.
The Use of Mother Tongue in Communicating Mathematics: Implication for Teaching and Learning of Mathematics
Authors: Esuong Uwase Uwase , Udo Ofonime Friday , Effiong Item Asuquo
Published: January 2024

Mathematics as a school subject is designed to solve the everyday problem created by human activities; these problems are domesticated in the different cultures of man all over the world. However, the performance of students keeps dwindling due to the westernize approach of teaching and learning mathematics. In other to solve this precarious situation this paper advocated the use of mother tongue in the teaching of mathematics. Mother tongue approach here refers to first-language education as a medium of instruction. The use of mother tongue in the teaching and learning of mathematics is meant to address the high functional illiteracy of Nigeria where language plays a significant factor. Using mother tongue to teach the basic concepts of numbers, operations and other concepts of mathematics helps build a strong foundation for the understanding and learning of higher mathematics. This approach is effective not only in getting the interest of students in the lesson but as a springboard in teaching new mathematical concepts, principles and in deepening student understanding on how mathematical operations or processes work. The mother tongue concepts of teaching and learning mathematics in this work shall be based on the following sub-topics: Numeration/Counting System, Basic Arithmetic Operations, Rhymes and Geometric Concepts. The paper completely reduced the Eurocentric mathematics beliefs of students and make them discover how best mathematics can be learning from their mother tongue. The paper recommended amongst others that teachers of mathematics should adopt the use of mother tongue in teaching mathematics in order to improve students understanding of the subject.
Ego-Identity as Determinants of University- Community Preference for GSM Service Providers in Ondo State, Nigeria
Authors: Olowe Modupe Oluwatoyin
Published: January 2024

Global System for Mobile Communications (GSM) operation has grown very rapidly to become a highly competitive business in the country. The popular network providers in Nigeria are MTN, Globacom (Glo), Airtel and Etisalat now 9mobile. The study investigated the strength of Ego-identity as determinants of university-community preference for GSM service providers in Ondo State, Nigeria. One research question and one hypotheses were formulated to guide the study. This study adopted a descriptive survey research design. The population comprised 38,631 undergraduate students, teaching and non-teaching staff of the four universities who were subscribers to the different service providers in Ondo State, Nigeria. Ten percent of the population was sampled, 3,865. Guttman split-half method was used for reliability of the study with r-value of Ego Identity, 0.783. Questionnaires were properly filled and used for analysis. The research questions were analyzed using descriptive statistics, standard deviation and percentage. The hypotheses were tested using Discriminant Function Analysis at .05 level of significance. The results showed that ego identity (Wilks Lambda 0.583 F (3,861) 918.709 P<0, 05) classifying 28.2% of respondent’s preferences. Based on the findings, it was recommended, among others, that the network providers should train and retrain their staff on how to rendered satisfactory services to their customers. The university community should endeavor to subscribe to the network that have high quality in order to ensure effectiveness and efficiency of its members
Estilo de Vida en Pacientes con Diagnóstico de Diabetes Tipo 2 de Más de 10 Años de Evolución Derechohabientes de la Umf No.9 Acapulco, Guerrero
Authors: Montes de Oca Salazar Karla Arely , Ocampo Rentería Teresa
Published: January 2024

Este estudio descriptivo, transversal y prospectivo evaluó el estilo de vida en 385 pacientes con diabetes tipo 2, con más de 10 años de evolución, pertenecientes a la UMF No. 9 en Acapulco, Guerrero. Realizado entre mayo y junio de 2023, el estudio utilizó el Instrumento IMEVID para medir el estilo de vida y empleó el programa SPSS versión 25 para el análisis de datos, centrando su atención en medidas de tendencia central. Los resultados mostraron que el sexo femenino predominó en la muestra, y más de la mitad de los pacientes indicaron tener un estilo de vida favorable. En contraste, los estilos de vida poco favorables y desfavorables fueron más comunes en pacientes masculinos. Los aspectos más afectados en aquellos con un estilo de vida desfavorable incluyeron la dieta, la actividad física y el apego al tratamiento. La conclusión principal del estudio es que, en esta población específica, prevalece un estilo de vida favorable, especialmente en mujeres entre 61 y 79 años, con una evolución de la enfermedad de 10 a 15 años. Este hallazgo subraya la importancia de las intervenciones focalizadas en el estilo de vida como parte integral del manejo de la diabetes tipo 2, destacando la necesidad de abordar específicamente la dieta, la actividad física y el apego al tratamiento en los planes de cuidado.
Política distributiva y descentralización en Chile y Perú
Authors: Livert Felipe , Mogollon Raymundo , Herrera Rivera Pablo
Published: January 2024

El artículo presenta evidencia de que la descentralización incrementa la inﬂuencia partidista en la asignación de recursos no programáticos. El modelo emplea un análisis de datos de panel y efectos ﬁjos usando datos que corresponden a transferencias intergubernamentales provenientes del nivel nacional, que pasan por el nivel regional y que están destinadas a inversión para los gobiernos locales de Chile (20082018) y Perú (2004 – 2013). Los resultados indican inﬂuencia política en la distribución de recursos. La distribución de recursos es usada tácticamente en ambos países en los años de elección presidencial. La aplicación de leyes que aumentan la descentralización política en Chile y Perú aumentó el sesgo político en la distribución de los recursos. Los resultados tienen implicancias políticas y permiten obtener una perspectiva comparada del desarrollo de las instituciones ﬁscales en ambos países. En un escenario continental, en que los países de América Latina están experimentando un fuerte proceso de descentralización, se sugiere avanzar en reformas que incrementen la transparencia, la rendición de cuentas y participación ciudadana. Adicionalmente, es recomendable limitar las asignaciones no programáticas, y brindar estabilidad a la distribución de recursos públicos.
Estructura económica y sincronización de los ciclos económicos
Authors: Gómez-Zaldívar Manuel , Gómez-Zaldívar Fernando
Published: January 2024

Estudios recientes documentan que la creciente integración económica entre México y los Estados Unidos, originada por el Tratado de Libre Comercio de América del Norte (TLCAN), transformó heterogéneamente las estructuras económicas de los estados de México. Este estudio provee evidencia que lo anterior alteró la naturaleza y el grado de sincronización económica entre ellos. Además, ilustra que existe una relación positiva, y cada vez más signiﬁcativa a partir de 1994, entre la sincronización económica y la soﬁsticación de las estructuras económicas de los estados [medida por el Índice de Complejidad Económica (ICE)]. Con mayor integración económica, los shocks se trasmiten más fácilmente entre las economías estatales con estructuras económicas similares, ya sea porque sus características las hagan sensibles a las mismas clases de shocks o porque se las transﬁeren unas a otras, al estar más vinculadas. Nuestros resultados complementan la comprensión de la evolución económica de los estados durante el periodo analizado.
CREATIVITY MANAGEMENT WITHIN THE AESTHETICAL SITUATION REGARDING THE IN-REAL OR DIGITAL FORM OF PARTICIPATION IN ARTS: ART RECEIVERS’ PERSPECTIVE
Authors: Szostak Michał , Sułkowski Łukasz
Published: January 2024

Because digitalisation of the aesthetical experience, a process speeded up by the not-yet-finished COVID-19 pandemic, should be considered in the context of growth or loss of artistry/creativity, this paper aims to assess the influence of the participation form in the aesthetical situation by receivers on the level of artistry/creativity potential loss. Assessment of the quality of participation by the receivers in each of five types of arts (musical arts, performing arts, literary arts, audio-visual arts, visual arts) was done using the same ten criteria for each type of art: satisfaction, pleasure, engagement, the possibility of experiencing catharsis, contact with the artwork itself, contact with the performer itself, comfort of participation, possibilities of shaping the aesthetical experience, own motivation to participate, easiness of participation. The literature review was run using NVivo Pro software. Data analysis (n = 221) was executed using IBM SPSS and Microsoft Excel. Answering the research hypotheses: H1) the digital form of participation in arts determines the level of quality of participation in the aesthetical situation by receivers; H2) the form of participation in art shapes the level of quality of participation in the aesthetical situation by receivers of each type of art differently: in musical arts, performing arts, literary arts and visual arts, in-real participation gives higher quality than digital participation; in audio-visual arts, in-real participation gives lower quality than digital participation. The research results may be helpful for: art creators wanting to choose the optimal way of distributing their artworks; art managers to better understand art receivers’ perspectives and their opinion about participation in arts in real or digitally; art receivers to compare their private opinion about the ways of participation in arts with the general opinion of art receivers.
APPROACHES TO TAX EVASION: A BIBLIOMETRIC AND MAPPING ANALYSIS OF WEB OF SCIENCE INDEXED STUDIES
Authors: Barbu Liliana , Horobeț Alexandra , Belașcu Lucian , Ilie Anca Gabriela
Published: January 2024

The primary objective of this study is to uncover and examine the patterns of scientific collaboration within the domain of tax evasion and tax avoidance spanning the years 1975 to 2022. To analyze the dissemination of knowledge on a worldwide scale, we investigated the interconnections among authors, journals, countries, and institutions. A total of 1456 publications were retrieved from the Web of Science repository. Bibliographic analysis and network visualization were conducted using CiteSpace. The publications analysed in this study consisted of 1,456 articles authored by 2478 scholars affiliated with 1355 institutions. The publications were distributed among 724 distinct journals and originated from 98 countries. The United States of America is found to be the most productive nation, with McGee, R.W. being recognised as the most prolific author. The League of European Research Universities is recognised as the most productive institution, whereas the Journal of Public Economics is identified as the most productive publication. The findings show that authors who exhibit high levels of productivity also tend to demonstrate a strong inclination toward collaboration. Furthermore, the findings reveal that the interest of the scholars in particular topics in this research has evolved over time.
Double Neutron Star Mergers: Are Late-time Radio Signals Overestimated?
Authors: Li Shao-Ze , Yu Yun-Wei , Gao He , Lan Lin
Published: January 2024

The coalescence of binary neutron stars can yield the expulsion of a fast-moving, quasi-isotropic material, which may induce thermal radiation and give rise to kilonova emission. Moreover, the interaction between the ejected material and the surrounding environment generates an external shock, which can result in a long-lasting radio signal that persists for several decades following the merger. In contrast to supernova ejecta, the kilonova ejecta exhibits a relatively lesser mass and higher velocity, and its expansion may ultimately result in the ejecta density becoming so low that the medium particles can freely pass through the ejecta. It would thereby lead to a kind of incomplete sweeping on the interstellar medium. Employing a toy model, our investigation reveals that such incomplete sweeping may considerably diminish the late-time radio radiation power, irrespective of whether the binary neutron star merger results in the formation of a black hole or a neutron star. Our findings thus imply that the previously reported radio upper limits for certain short gamma-ray bursts (GRBs) may not necessarily place stringent constraints on the presence of a long-lived magnetar remnant in these short GRBs.
Flashlights: Properties of Highly Magnified Images Near Cluster Critical Curves in the Presence of Dark Matter Subhalos
Authors: Williams Liliya L. R. , Kelly Patrick L. , Treu Tommaso , Amruth Alfred , Diego Jose M. , Li Sung Kei , Meena Ashish K. , Zitrin Adi , Broadhurst Thomas J. , Filippenko Alexei V.
Published: January 2024

Dark matter subhalos with extended profiles and density cores, and globular star clusters of mass 106–108
M
⊙ that live near the critical curves in galaxy cluster lenses can potentially be detected through their lensing magnification of stars in background galaxies. In this work, we study the effect such subhalos have on lensed images, and compare to the case of more well-studied microlensing by stars and black holes near critical curves. We find that the cluster density gradient and the extended mass distribution of subhalos are important in determining image properties. Both lead to an asymmetry between the image properties on the positive- and negative-parity sides of the cluster that is more pronounced than in the case of microlensing. For example, on the negative-parity side, subhalos with cores larger than about 50 pc do not generate any images with magnification above ∼100 outside of the immediate vicinity of the cluster critical curve. We discuss these factors using analytical and numerical analysis, and exploit them to identify observable signatures of subhalos: Subhalos create pixel-to-pixel flux variations of ≳0.1 mag on the positive-parity side of clusters. These pixels tend to cluster around (otherwise invisible) subhalos. Unlike in the case of microlensing, signatures of subhalo lensing can be found up to 1″ away from the critical curves of massive clusters.
Accessing the Host Galaxies of Long Gamma-Ray Bursts with Next-generation Telescopes
Authors: Lan Guang-Xuan , Li Ye , Li Zhuo
Published: January 2024

We present a method to estimate the detection expectations of host galaxies of long gamma-ray bursts (LGRBs) in the grizJHKL bands. It is found that given the same limiting magnitude

m

grizJHKL
,
lim

in each band, the z band produces the largest number of overall LGRB hosts and low-mass hosts (M
* ≤ 108
M
⊙) at

m

grizJHKL
,
lim

≳
26

mag. For the detection of high-redshift LGRB hosts (redshift ≥5), it is recommended to prioritize the L band, due to its good performance at both low and high limiting magnitudes. We specifically estimate the expectation of LGRB host detection with

m

grizJHKL
,
lim

=
28

mag, which the James Webb Space Telescope can partially attain. We find that there may exist 116, 259, 277, 439, 266, 294, 274, and 316 LGRB hosts, including 0.54, 31, 28, 143, 12, 20, 14, and 35 low-mass ones in the grizJHKL bands and 13, 14, 15, 14, and 15 high-redshift ones in the zJHKL bands, for 15 yr Swift LGRBs with S ≥ 10−6 erg cm−2. The results show that the study of LGRB hosts under next-generation observational conditions holds significant potential, especially for low-mass host studies. However, it appears that the deeper sensitivities of galaxy telescopes may not significantly enhance statistical studies of high-redshift hosts. Strategies aimed at increasing the number of distant LGRB hosts may require the expansion of high-redshift LGRB detections.
The trouts of the Marmara and Aegean Sea drainages in Türkiye, with the description of a new species (Teleostei, Salmonidae)
Authors: Turan Davut , Bayçelebi Esra , Aksu Sadi , Oral Münevver
Published: January 2024

The taxonomic status of native trout species of the Marmara and Aegean Sea drainages is evaluated and three species, Salmo duhani, S. coruhensis and S. brunoisp. nov., are recognized. Salmo brunoi, a new species, is described from the Nilüfer River, a tributary of the Susurluk River. It is distinguished by a general brownish body color in life; few black spots (fewer than 60) on the body, generally scattered on the back and the upper part of the flank, rarely in the median part; few (fewer than 40) and small (smaller than pupil) red spots on the body, scattered on the median part and lower half of the flank; a number of black and red spots not increasing with size in both sexes; a long adipose fin (adipose-fin height 8–9% SL); a short distance between adipose-fin and caudal-fin (12–14% SL); and a short anal fin (anal-fin height 12–15% SL). Salmo brunoisp. nov. is separated from the rest of the Marmara and Aegean trouts of Anatolia based on genome-wide distributed 187.385 unlinked SNP markers. According to the best of the authors’ knowledge, whole genome data is used for the first time here to characterize a new species of trout.
Population variation of Diapoma pampeana (Characiformes, Characidae, Stevardiinae) from an isolated coastal drainage in Uruguay, with new records: comparing morphological and molecular data
Authors: Vanegas-Ríos James Anyelo , Serra Alanís Wilson Sebastián , Azpelicueta María de las Mercedes , Litz Thomas , Malabarba Luiz Roberto
Published: January 2024

Diapoma pampeana was recently described to occur in the upper Negro basin in Uruguay and Brazil. An isolated population tentatively identified as D. pampeana from the Pando stream, a perturbed coastal drainage in Uruguay, is studied and compared under the light of morphological and molecular data to test if there is evidence to consider it as a separate species. New geographical records for the species are presented and included in the comparisons. The specimens analyzed were pooled into four groups: Pando, Santa Lucía, Middle Negro and Upper Negro. We analyzed 32 morphological characters using statistical procedures and recovered a COI-based phylogeny of different populations of D. pampeana to test if they may represent different species. Size-corrected PCA revealed that the Pando and Upper Negro groups are greatly diverging in both morphometric and meristic data along PC1 (mainly by the snout to dorsal-fin origin, dorsal to adipose-fin origins, number of longitudinal scales and predorsal scales). This deviating pattern was also obtained in a cluster analysis. The Santa Lucía and Middle Negro groups were found to be intermediate morphotypes. In contrast, molecular analyses revealed that the Pando and Upper Negro specimens resemble genetically and, thus, are placed together in the Neighbor-joining and Bayesian topologies, as part of a monophyletic Diapoma. We proposed that the Pando population, despite its deviating morphology observed, can be classified as D. pampeana. Therefore, this population constitutes a remarkable example of an isolated population that is morphologically divergent but genetically similar to the geographically most distant conspecific population.
A new species of land snail, Xanthomelon amurndamilumila, from the North East Isles off Groote Eylandt (= Ayangkidarrba), Gulf of Carpentaria, Australia (Stylommatophora, Camaenidae)
Authors: Köhler Frank , Willan Richard C. , Bourke Adam J. , Barden Paul , Shea Michael
Published: January 2024

This paper introduces Xanthomelon amurndamilumilasp. nov., a newly-discovered land snail species inhabiting the North East Isles, offshore from Groote Eylandt (= Ayangkidarrba), north-western Gulf of Carpentaria, in the Northern Territory, Australia. Specimens of this species were first collected during the 2021 Bush Blitz expedition to Groote Eylandt, a large offshore archipelago previously unexplored for land snails. The taxonomic status of the new species was established through a comprehensive analysis of comparative morphology and mitochondrial genetics: X. amurndamilumila forms a maximally supported clade closely related to X. arnhemense and is characterised by a unique combination of morphological characteristics, including smaller shell size, distinctive sculpture of collabral ridges and specific features of its reproductive anatomy. The genetic divergence and phylogenetic relationships suggest historical isolation. While the discovery of X. amurndamilumilasp. nov. enriches our understanding of land snail diversity in the Northern Territory, its conservation status is of concern on North East Island because of habitat degradation caused by feral deer.
Simulation of tumor density evolution upon chemotherapy alone or combined with a treatment to reduce lactate levels
Authors: Raad Hussein , Allery Cyrille , Cherfils Laurence , Guillevin Carole , Miranville Alain , Sookiew Thomas , Pellerin Luc , Guillevin Rémy
Published: January 2024

In this study, we introduced a mathematical model mimicking as much as possible the evolutions and interactions between glioma and lactate in the brain, in order to test different therapies and administration protocols. We simulated both glioma cell density evolution and lactate concentration, and considered two therapies: chemotherapy and a treatment targeting lactate production. Three different protocols for administrating the therapies were tested. We compared the efficiency of the combined therapies, depending on the administration protocols and the dosage of the drugs, in order to evaluate the importance of controlling lactate production. Results show that the use of an agent to reduce lactate concentration permits one to significantly reduce the dose of the chemotherapeutic drug.
On the boundedness of solutions of some fuzzy dynamical control systems
Authors: Kahouli Omar , Turki Amina , Ksantini Mohamed , Hammami Mohamed Ali , Aloui Ali
Published: January 2024

The asymptotic behavior of solutions of fuzzy control systems is a component of the study of fuzzy control theory. The study of stability for T-S (Takagi-Sugeno) fuzzy systems, which process qualitative data through linguistic expressions, is the subject of this paper. Asymptotic stability is conservative in many real-world applications due to measurement noise and other disruptions. The ultimate limit, which indicates that the mistakes stay in a specific area close to the origin after a long enough amount of time, is a crucial characteristic that is frequently defined for such systems. We are interested with the problem of the state feedback controller for T-S fuzzy models with uncertainties where the global exponential ultimate boundedness of solutions is studied for certain fuzzy control systems. We use common quadratic Lyapunov function and parallel distributed compensation controller techniques to study the asymptotic behavior of the solutions of fuzzy control system in presence of perturbations. An example demonstrating the validity of the main result is discussed.
Torque control strategy of electric racing car based on acceleration intention recognition
Authors: Yuan Anlu , Zhang Tieyi , Xiong Lingcong , Zhang Zhipeng
Published: January 2024

A torque control strategy based on acceleration intention recognition is proposed to address the issue of insufficient power performance in linear torque control strategies for electric racing cars, aiming to better reflect the acceleration intention of racing drivers. First, the support vector machine optimized by the sparrow search algorithm is used to recognize the acceleration intention, and the running mode of the racing car is divided into two types: Starting mode and driving mode. In driving mode, based on the recognition results of acceleration intention, fuzzy control is used for torque compensation. Based on the results of simulation and hardware in the loop testing, we can conclude that the support vector machine model optimized using the sparrow search algorithm can efficiently identify the acceleration intention of racing drivers. Furthermore, the torque control strategy can compensate for positive and negative torque based on the results of intention recognition, significantly improving the power performance of the racing car.
Reconstruction of shear force in Atomic Force Microscopy from measured displacement of the cone-shaped cantilever tip
Authors: Hasanov Alemdar , Kawano Alexandre , Baysal Onur
Published: January 2024

We present a new comprehensive mathematical model of the cone-shaped cantilever tip-sample interaction in Atomic Force Microscopy (AFM). The importance of such AFMs with cone-shaped cantilevers can be appreciated when its ability to provide high-resolution information at the nanoscale is recalled. It is an indispensable tool in a wide range of scientific and industrial fields. The interaction of the cone-shaped cantilever tip with the surface of the specimen (sample) is modeled by the damped Euler-Bernoulli beam equation $ \rho_A(x)u_{tt} $ $ +\mu(x)u_{t}+(r(x)u_{xx}+\kappa(x)u_{xxt})_{xx} = 0 $, $ (x, t)\in (0, \ell)\times (0, T) $, subject to the following initial, $ u(x, 0) = 0 $, $ u_t(x, 0) = 0 $ and boundary, $ u(0, t) = 0 $, $ u_{x}(0, t) = 0 $, $ \left (r(x)u_{xx}(x, t)+\kappa(x)u_{xxt} \right)_{x = \ell} = M(t) $, $ \left (-(r(x)u_{xx}+\kappa(x)u_{xxt})_x\right)_{x = \ell} = g(t) $ conditions, where $ M(t): = 2h\cos \theta\, g(t)/\pi $ is the moment generated by the transverse shear force $ g(t) $. Based on this model, we propose an inversion algorithm for the reconstruction of an unknown shear force in the AFM cantilever. The measured displacement $ \nu(t): = u(\ell, t) $ is used as additional data for the reconstruction of the shear force $ g(t) $. The least square functional $ J(F) = \frac{1}{2}\Vert u(\ell, \cdot)-\nu \Vert_{L^2(0, T)}^2 $ is introduced and an explicit gradient formula for the Fréchet derivative of the cost functional is derived via the weak solution of the adjoint problem. Additionally, the geometric parameters of the cone-shaped tip are explicitly contained in this formula. This enables us to construct a gradient based numerical algorithm for the reconstructions of the shear force from noise free as well as from random noisy measured output $ \nu (t) $. Computational experiments show that the proposed algorithm is very fast and robust. This creates the basis for developing a numerical "gadget" for computational experiments with generic AFMs.