bluuebunny/crossref_metadata_2025 huggingface dataset:
Rheological properties of hyaluronic acid-based fillers for facial cosmetic aesthetics
Authors: Furtado Gisele Rosada Dônola , Barbosa Kledson Lopes , Dametto Alessandra Cristina , Sisnando Andréa Lisboa , Silva Luiz Carlos Foletto da , Souza José Reinaldo Araújo , Oliveira Ricardo César Gobbi de , Albergaria-Barbosa José Ricardo de , Rizzatti-Barbosa Célia Marisa
Published: January 2023

Hyaluronic acid-based dermal fillers are the most used materials in cosmiatry, and their clinical implications are linked to their viscoelastic properties. This study aimed to determine the rheological behavior of HA products used in Brazil by changing specific physicochemical characteristics under different test frequencies. Laboratory analyses of 0.9 mL of samples were performed in a TA-Instruments AR-1500ex Rheometer at 25 °C, at oscillation frequencies of 100, 10, 1, and 0.1 radians/second, considering the measurements of G′, G′′, and Tan δ. The value of G' increased as the oscillation frequencies were increased. In parallel, the changes in G" were the ones that varied the most for frequencies 0.1 and 1 radian/second. The maximum G' was observed with Hialurox Ultra Lift® 26 mg/g (793.45; 554.06; 423.44 Pa, 100, 10 and 1 rad/s, respectively). While the lowest G' values were obtained with Rennova Ultra Deep® (43.01; 19.75; 10.75 and 10.42 Pa at 100, 10, 1, 0.1 rad/sec, respectively). The changes that occurred in the investigated properties indicated that hyaluronic acid-based fillers vary when subjected to different conditions of shear rate, which should be considered in their clinical indication for choosing the most appropriate material according to the region to be treated.
Avaliação do desempenho comportamental de um algoritmo de mineração de texto em conexões com internet nos municípios de Conceição do Araguaia e Redenção - PA
Authors: Santos Wilker José Caminha dos , Carr Renato Ferreira , Lopes Rogerio Santiago , Silva Junior Daveny Jales da , Santos William Gabriel Barbosa dos , Ribeiro Edgard Augusto Nascimento , Santos Armando José de Sá
Published: January 2023

Este estudo teve como objetivo geral avaliar o desempenho comportamental de um método de mineração de texto escrito em Python com atributos voltados para redes bayesianas em conexões de baixa velocidade nas cidades de Conceição do Araguaia e Redenção-PA localizadas no interior do estado do Pará. Dentre os autores pesquisados para a constituição conceitual deste trabalho, destaca-se Caminha et al (2017), Conte et al (2016), Santana et al (2016), Almeida et al (2016) e Mata et al (2013). A metodologia utilizada se encontra (Caminha et al, 2017), que por sua vez, se enquadra como qualitativa-analítica, em virtude de buscar trabalhar no aprofundamento da avaliação de desempenho comportamental com base de textos minerados da rede social twitter. As conclusões mais relevantes deste trabalho foram decorrentes da comparação dos resultados obtidos na cidade de Conceição do Araguaia e Redenção, onde foi possível observar inconformidades no desempenho do tráfego de dados de ambas as cidades, tanto para aspectos positivos quanto para negativos apesar da igualdade na velocidade do link em ambas as cidades nos anos de 2016, 2017, 2021 e 2022, a fim de comparar a existência de uma evolução no seu comportamento.
Rede de atenção à saúde bucal para Pessoas com Deficiência: desafios e potencialidades da Atenção Primária à Saúde
Authors: Carvalho Leticia Ferreira de , Leite Isabel Cristina Gonçalves , Farah Beatriz Francisco
Published: January 2023

A Atenção Primária à Saúde (APS) é o centro de comunicação das Redes de Atenção à Saúde, tendo a função de coordenar o cuidado. O objetivo deste trabalho foi analisar a Rede de Atenção à Saúde Bucal para Pessoas com Deficiência (RASB-PcD) e identificar os principais desafios e potencialidades para que a APS cumpra seu papel coordenador. Trata-se de uma pesquisa de abordagem qualitativa, exploratória-descritiva com coleta de dados por meio de grupos focais e entrevistas, com profissionais de saúde bucal que atuam em microrregiões mineiras. A técnica para a análise dos dados foi a análise do conteúdo de Laurence Bardin, com auxílio do software IRAMUTEQ. O fluxo assistencial de referência nesta RASB-PcD está instituído, mas apresenta inconsistências, já o fluxo de contrarreferência demonstra fragilidades. Os critérios e protocolos para acesso ao serviço hospitalar precisam ser melhor discutidos e os exames pré-operatórios realizados em tempo oportuno. A oferta de vagas nos serviços especializados e hospitalar foi identificada como um desafio. Melhorar a comunicação e a articulação entre os profissionais, através de estratégias sólidas de Apoio Matricial e de educação permanente, emergiu como uma potencialidade para que a APS possa coordenar o cuidado, garantir sua longitudinalidade e proporcionar atenção integral às PcD.
Influência do estilo de vida no índice de massa corporal em estudantes universitários da região Norte do Brasil durante o período de isolamento social da pandemia do COVID-19
Authors: Feijó Raiany de Souza , Domingues Wagner Jorge Ribeiro , Brandão Emely Kércia Santiago de Souza , Guariglia Débora Alves
Published: January 2023

O estilo de vida representa um conjunto de ações cotidianas refletidas em atitudes e valores das pessoas. Durante a pandemia, registrou-se a redução do tempo utilizado na atividade física e mudanças no hábito alimentar, possivelmente resultou no aumento do comportamento sedentário e afetou de forma negativa o índice de massa corporal (IMC) de estudantes universitários da região Norte do Brasil. O objetivo foi identificar a influência do estilo de vida no IMC de estudantes universitários da região Norte do Brasil, durante isolamento social causado pela pandemia do COVID-19. Tratou-se de um estudo observacional de caráter transversal, composto por 432 alunos de graduação e pós-graduação de universidade pública e privada, de ambos os sexos, com média de idade de 26,2 ± 8,6 anos. O estilo de vida foi verificado pelo questionário “Estilo de Vida Fantástico'' versão brasileira realizada por Añez, Reis & Petroski (2008), sendo classificado em pontos, sendo Excelente (85- 100), Muito bom (70-84), Bom (55-69), Regular (35-54) e Necessita melhorar (0-34). O IMC foi calculado pela razão entre a massa corporal e estatura elevada ao quadrado. Os participantes foram classificados em Abaixo do peso, Peso normal, Sobrepeso e Obesidade. A influência do estilo de vida no IMC foi verificada pelo teste de Qui-Quadrado, com erro alfa de 5%. Houveram associações estatisticamente significativas entre estilo de vida e IMC com P = 0,003. Os achados sugerem que o estilo de vida influencia no IMC de estudantes universitários, mostrando que estudantes classificados com estilo de vida bom estavam com IMC normal.
As premissas do Banco Mundial para a formação docente: uma análise crítica
Authors: Santos Felipe Néo dos , Néo Danielle de Menezes Vieira , Barbosa Fabiano Geraldo , Silva Rosângela Ribeiro da , Almeida Emanoel Rodrigues , Araújo Adéle Cristina Braga , Silva Simone Cesar da
Published: January 2023

O presente estudo teve como objetivo geral analisar as intervenções do Banco Mundial na formação docente, sendo os objetivos específicos: a) averiguar as transformações ocorridas na formação docente em países em desenvolvimento; b) investigar os impactos das mudanças promovidas pelo Banco Mundial a formação docente no Brasil; e c) verificar as condicionalidades do Banco Mundial ao fortalecer as premissas do capital. Em termos metodológicos, a pesquisa se baseou no método materialismo histórico dialético, a partir de uma abordagem qualitativa e de uma investigação bibliográfica. Para tanto, tomou-se, fundamentalmente, como referências as proposições teóricas dos seguintes autores: Pansardi (2011), Rabelo et al (2015), Corte, Sarturi e Nunes (2018), Freitas (2018), Soares e Silva (2018), Santos e Orso (2020), Zank e Malanchen (2020), dentre outros. Os resultados e discussões apontaram que as transformações educacionais ocorridas nas últimas décadas colaboram para a segmentação da formação docente com o protótipo pragmático concentrado nos saberes experienciais de professores/as, depreciando os conhecimentos científicos que fundamentam à docência, bem como, as indicações de agências internacionais circundam-se na limitação de custos e de tempo na educação para atingir as metas e a proliferar proveitos do capital. Nas considerações finais, salientou-se que as modificações ocorridas na educação brasileira têm como propósito realizar o projeto educacional do capital, com esse fim, potencializam as transformações oportunas para o fortalecimento do capitalismo, assim, impactaram a formação docente de tal modo que direcionaram a formação e a prática pedagógica, a fim de preparar os/as estudantes para o mercado de trabalho.
Gestão de processos: abordagem da administração moderna
Authors: Nyland Joana Josiane Andriotte Oliveira Lima
Published: January 2023

O gerenciamento de processos de negócios é importante porque processos de negócios eficazes são cruciais para o sucesso da empresa. Dessa forma, o presente trabalho tem como objetivo compreender a Gestão de processos no âmbito da Administração, visando assim os negócios. Por meio, de uma revisão bibliográfica de caráter qualitativo documental, dessa forma, o conhecimento de outros pesquisadores será utilizado como base teórica para expandir as fronteiras do conhecimento por meio de livros, artigos, periódicos e papers, e desenvolverão trabalhos atuais. O gerenciamento de processos de negócios (BPM) é uma abordagem estruturada para melhorar os processos que as organizações usam para realizar o trabalho, atender seus clientes e gerar valor comercial. Um processo de negócios é uma atividade ou conjunto de atividades que ajuda a atingir as metas de uma organização, como aumentar os lucros ou promover a diversidade da força de trabalho. Os resultados revelam que a função de Administradores é a função que um gerente de processo assume ao controlar um processo para que funcione conforme planejado. O principal objetivo da função de Administradores é garantir que o plano seja implementado sem quaisquer desvios. É importante observar que o BPM não é uma tecnologia de automação específica. Embora geralmente envolva automatizar várias tarefas, é uma mentalidade e uma metodologia que permite que as pessoas agilizem as operações. Isso pode acontecer com ou sem tecnologia.
Racismo algorítmico: uma revisão de literatura
Authors: Nyland Joana Josiane Andriotte Oliveira Lima
Published: January 2023

O racismo algorítmico é um tema que tem levantado diversas discussões na sociedade em que vivemos, pois, as organizações fazem uso da desculpa de lucratividade para institucionalizar o racismo estrutural ao qual vemos em nossa sociedade. A partir do debate desse tema, conseguimos propor alternativas reais para o combate dessa prática e mitigar esse tipo de atitude por parte da indústria tecnológica. O objetivo deste estudo foi apresentar uma discussão a partir de fontes bibliográficas que estruturam um projeto no ensino superior a partir do tema gerador racismo algorítmico. O adorno metodológico para estruturação dos dados ocorre a partir de uma revisão integrativa de literatura, permitindo uma conexão entre o autor e os dados coletados para o desenvolvimento qualitativo de sua discussão. Os resultados propiciam uma reflexão frente a importância desse tema para a sociedade atual, que vive em um momento de transição onde costumes antigos já não são bem-vistos pela sociedade e alguns até são criminalizados. Desta forma discussões como essas se fazem de extremas importância.
The role of attention and information for behavioral change
Authors:   , Lancee Bora Saskia
Published: January 2023

This dissertation aims to analyze the role of attention and information for behavioral change in a policy setting. All projects experimentally study information search and attention either directly or indirectly. The dissertation begins with offering a theoretical and experimental benchmark; it discusses the main facet of search and attention and the role of inattention in informed decision-making. The chapters are illustrations of inattention in policymaking that show the different aspects of inattention in the making, execution, and testing of different policies. In the first chapter, a theoretical framework is proposed and discussed. Thereafter it discusses the search and attention of civil servants in the policy exploration and development phase. Two applications of inattentive decision-makers are studied in the second part of the dissertation. One application tests a policy to help inattentive decision-makers in a consumer context, and the other examines the behavioral response to inattentive policy execution in the realm of taxation.
EXPERIENCE WITH THE ACTION ART IN THE COURSE OF LIFE OF PERSON: FROM EXPERIENCE TO THERAPY
Authors: KOVÁČOVÁ BARBORA , ŠEVČOVIČ MARTIN , VALACHOVÁ DANIELA
Published: January 2023

The paper describes the real possibilities of using the action art in the course of one’s life from an early age to the old age. The paper presents specific artistic outputs called situational-art-action-models designed for different age groups. These models prompt the participants themselves to action, in particular to tell (re-create) a story, regardless of whether the story was finished or not. The ways in which the participants express themselves are different, as are the different environments in which the art takes place. Unambiguous action art blurs the boundaries, breaks rules, and gives the participants the opportunity to present a person in different forms and looks. The paper is supplemented by photo documentation of art-action models.
Comparison of Pd- and Ru-Containing Composites in the Process of Selective Reduction of Furfural
Authors: Salnikova K. , Tsvetkova P. , Matveeva V. , Sidorov A. , Sulman M.
Published: January 2023

A wide range of important chemicals derived from biomass, including furfural, 5-hydroxymethylfurfural, levulinic acid, glycerin, etc., are obtained in large quantities from agricultural waste (cellulose and hemicellulose). Among them, furfural derived from C5or C6 sugars is considered one of the top 30 platform chemicals derived from biomass. The reduction of furfural to furfuryl alcohol can be used to produce a variety of chemicals, including synthetic fibers, resins, foundry binders, binders, and other important platform molecules. Obtaining furfuryl alcohol using the selective reduction of furfural is a complex multi-stage process. The hydrogenation reaction of furfural has recently been carried out on composites based on Group VIII metals (Ru, Rh, Pd, Os, Ir, Pt). Therefore, a comparison was made of the catalytic properties of the 3%Pd/Al2O3and 3%Ru/Al2O3 composites using the selective reduction of furfural to furfuryl alcohol. For a better understanding of the catalytic properties of both composites, the surface and porosity of the catalysts synthesized on its basis were determined by the BET method. For a qualitative analysis of isotherms, the Brunauer classification of isotherms is used, which is based on the relationship between the isotherm shape and the adsorption mechanism. Therefore, comparison of the experimentally obtained data with the shape of the isotherm of this classification allows us to make an assumption about the adsorption mechanism and the pore size in the material under study.
XPS Study of Composite Systems Based on Ruthenium
Authors: Tsvetkova P. , Salnikova K. , Bykov A. , Matveeva V. , Sulman M.
Published: January 2023

Based on the analysis of survey XPS spectra of 3%Ru/Al2O3 and 3%Ru/SPS catalyst samples before and after the catalytic test, the qualitative and quantitative elemental composition of the surface of these samples was established. Conditions for the 3% Ru/Al2O3 catalyst before the catalytic test of hydrated ruthenium (IV) was 23% and ruthenium (IV) oxide — 45%, respectively, and after — hydrated ruthenium (IV) was 21% and ruthenium (IV) oxide — 37%, respectively. Conditions for the catalyst 3% Ru/SPS before the catalytic test hydrated ruthenium (IV) was 29% and ruthenium (IV) oxide — 3%, respectively, and after — hydrated ruthenium (IV) was 22% and ruthenium (IV) oxide — 2 %, respectively.
Introduction of Some Medicinal Species of the Rhaponticum Genus
Authors: Abdimamatova E. , Attokurov K. , Abdyrakhmanova Zh.
Published: January 2023

In recent years, there has been a growing interest in medicinal plants and the use of drugs based on these plants. What is the reason for interest in medicinal plants: firstly, they have a slight effect on human body, without causing additional negative consequences during treatment, low toxic substances, and secondly, in addition to the active substance, the plant contains a lot of biologically active substances necessary for body and its healing properties. As shown above, medicinal plants are more important than synthetic, chemically derived drugs. Therefore, despite of chemicals variety, use of plants in medicine will always remain relevant. Research objectives: study of the biomorphology of introducents of the Rhaponticum genus and their seed propagation. Selection of scientific and popular information about the studied species of the Rhaponticum genus. To study biology of the seed and reproduction of the studied species. Phenological observations of introduced species of the Rhaponticum genus. Study of biomorphology of introduced species of the genus and their reproduction from seeds were performed. Research results: two studied species of Rhaponticum genus can be propagated by seeds in conditions of Osh. Conclusions:obtained raw materials (flowers, rhizomes) can be processed and used as a medicine in scientific and traditional medicine. Medicines prepared from their roots, rhizomes and flowers are used as stimulants for various diseases.
Chemical Composition and Pharmacological Activity of Plants of the Hypericum L. Genus
Authors: Jahangirova I. , Zulfugarova M. , Hajiyeva E. , Karimova Z.
Published: January 2023

The purpose of this work was to present the results of summarizing the literature data on the chemical composition and pharmacological activity of the Hypericum L. genus. The chemical composition of St. John’s wort (Hyperici herba) has been studied quite fully within the Eurasian area of the species; more than 80 components have been identified. The main biologically active compounds of raw materials are anthracene derivatives (hypericin), flavonoids (rutin, quercetin, hyperozoid), phenylpropanoids (chlorogenic acid) and hyperforin. The review article presents physical constants and spectroscopic ((-NMR) proton magnetic resonance, (13C NMR) 13C nuclear magnetic resonance, (-UV) ultraviolet, (-IR) infrared) interpretations of biologically active substances obtained from secondary metabolites from species belonging to genus. The results of pharmacognostic and pharmacological studies determine the feasibility of clinical trials of St. John’s wort raw materials drugs and their use in a wide therapeutic range in the complex treatment of diseases. Herba St. John’s wort is a promising source of raw materials for obtaining antibacterial, antiviral, anti-inflammatory, astringent, diuretic, antidepressant, antioxidant, anticarcinogenic, immunotropic and adaptogenic agents.
Modern Technologies Application in Water Bioresources and Aquaculture
Authors: Karimova R. , Rustamova J.
Published: January 2023

The production and use areas of aquatic plants are investigated in the article. In recent times, the development of fishing and the all-round use of aquatic plants (as food, the purchase of environmentally oil, as fertilizer) is one of the main issues of our day. Macroalgae are the basis of the cultivated sea products. Mainly, brown algae — laminaria, fucus, red algae — Kappaphycus alvarezii and Eucheuma are widely used for both food and alginate production. Spirulina algae, a representative of blue-green algae living in freshwater basins is one of the most cultivated and widely used algae. The fact that its composition is rich in proteins and vitamins creates the basis for the widespread use of algae. Algae thallome contains 60% protein, amino acids, oils, mineral salts, and fatty acids, which help to strengthen the immune system and eliminate anemia. In addition, biological substances obtained from algae active substances are easily absorbed by the body, it is one of the important substances for the regeneration of liver cells.
Analysis of the Efficiency of Hydraulic Fracturing With Preliminary Repair and Insulation Works at Facilities With Uneven Production of Reserves
Authors: Kukarskikh D. , Biryukova O. , Nanishvili O.
Published: January 2023

The paper analyzes the efficiency of hydraulic fracturing with preliminary repair and insulation work at facilities with uneven production of reserves. The geological and physical characteristics of the BS102-3formation by field-geological sites are given. The results of the conducted studies on the impact of repair and insulation work on the efficiency of hydraulic fracturing for various geological and commercial sites are presented.
Study of the Salt Composition of Some Rivers of the Lerik District
Authors: Mammadova A. , Aliyev S.
Published: January 2023

The article is devoted to the study of the ionic and salt composition of the rivers of the Lerik District of the southern part of Azerbaijan. The results of analyzes of the river waters selected as the object of the study show that there were no serious processes of mineralization in the rivers. The salinity of the river waters of the Lerik District (the Bilnа River, river waters taken from the villages of Mastail, Lankaranchay, Konjavuchay) varied within the range of 0,440-0.674 g/l. The composition of ions in these water sources varied depending on the rivers.
Creation of New High-Productive Tobacco Varieties in the Sheki-Zakatala Economic Region
Authors: Kazimov G. , Alieva A. , Abdullaeva N.
Published: January 2023

The article shows the implementation of selection and varietal studies on 70 samples, consisting of 35 varieties of tobacco collection nurseries and 35 hybrid selection materials, at the Zakatala Regional Experiment Station in the Sheki-Zakatala economic region. It was determined that the height of the plant in the collection area varied between 170 (Samsun-155, Samsun short) and 335 (106 blue form) cm. Thus, in the conditionally named Selected-2016 form, the height of the plants was 268 cm, and in the Virginia AZ form it was 282 cm. The maximum number of leaves was 50 in Zakatala Dubek varieties. The dimensions of the leaf blade were the highest in the Krupnolist variety with a width of 37 cm, and in the Virginia KY 160 variety with a length of 62 cm. Vegetation periods varied between 107-132 days. The height of the plant in the selection area varied between 180-295 cm. Thus, the height of the plants differed from the others with the highest being 295 cm in Virginia-20 × Zakatala Dubek and Virginia-20 × 106 blue form hybrids. The number of leaves was 49 in Virginia-20 × Zakatala Dubek form. The dimensions of the leaf blade were observed to be 64 cm in length in Virginia NC-71 × Zakatala Dubek × Virginia-20 complex pollination, and 37 cm in width in 106 blue form × Burley-122 hybrid. Vegetation periods varied between 115-129 days. In the collection area, it was observed that the highest yield indicator was 39.0 hwt/ha in Burley TN-90 varieties, and the lowest was 27.1 hwt/ha in Samsun short stature variety. Zakatala Dubek variety has the highest yield of commodity type I-II 90%, III-IV-10% and it differs from others. In the hybrid field, the highest yield index was 39.7 hwt/ha in the blue form of Virginia-20 × 106, and the lowest was 27.9 hwt/ha in the Virginia-548 × Virginia KY-160 variant. Virginia-20 × Zakatala Dubek variant had the highest yield of commodity species I-II 92%, III-IV-8% and differed from others. In 2021, 11 new hybrids were obtained as a result of selection works.
Indicators of the Cytokine Profile in Children with Erosive-ulcer Lesions of the Gastrointestinal and Duodenum
Authors: Kozhonazarova G.
Published: January 2023

The incidence of erosive and ulcerative lesions (EUI) of the stomach and duodenum in children in recent years has a high prevalence and the trend towards their growth continues. Despite numerous scientific studies, many questions remain unsolved, including the prevention of relapses and the chronicity of the process. In this regard, the aim of the study was to study the cytokine profile in children with erosive-ulcer lesions of the mucous membrane of the stomach and duodenum. 167 children with EUP (main group) and 50 children with functional disorders of the digestive system (control group) were examined. All children underwent a blood serum test for pro- and anti-inflammatory interleukins — IL1, 4, 6 and TNF. As a result of the study, it was found that the children of the main group showed an increase in all groups of cytokines before treatment, in contrast to the control group, where all indicators were within the normal range. In addition, in 26.9-37.1% of patients of the main group, the level of interleukins remained elevated after treatment. Conclusions: the change in the cytokine profile in dynamics is of great prognostic value for the study of inflammatory and degenerative processes in the mucous membrane of the stomach and duodenum and reflects the effectiveness of the treatment.
Risk Factors for Erosive-ulcer Diseases of the Mouth in Children
Authors: Kozhonazarova G.
Published: January 2023

Erosive-ulcer diseases of the oral cavity in children reach 9% of the prevalence among inflammatory diseases of the dentition and have a tendency to recur and chronicize the process. At the same time, the issues of etiopathogenesis remain unresolved to the end, and therefore the purpose of this work is to study the risk factors for the occurrence of erosive-ulcer lesions (EUL). Her study was conducted on the basis of the National Center for Maternity and Child Welfare. A retrospective analysis of the histories was carried out — 548 children who underwent inpatient treatment in the department of maxillofacial surgery. 100 patients with relapses of oral EUL were observed on an outpatient basis in the department of gastroenterology, where they underwent an in-depth clinical, laboratory and instrumental study. Risk factors were studied using a specially designed questionnaire. In the course of the study, it turned out that the EUL of the oral cavity in children is mainly found in preschool children, no special differences in the sex composition were found. It was revealed that the first significant factor is the pathology of the gastrointestinal tract up to 1 year (OR=324.927, PPV=92%, p<0.05). Next in rank significance (descending OR value — odds ratio) are neonatal pathology (OR=67.992, PPV=91%, p<0.05), nutrition quality (OR=47.861, PPV=94%, p<0.05 ), diseases of the gastrointestinal tract in relatives (OR=19.636, PPV=91%, p<0.05), diet (OR=4.644, PPV=89%, p<0.05), feeding (OR=3.597, PPV= 88%, p<0.05) and the course of pregnancy (OR=1.751, PPV=86%, p<0.05). This study allows you to focus on the most significant risk factors and continue the study to find the most optimal, affordable methods of research and treatment at all levels of healthcare. Considering the foregoing, the contingent of patients with erosive and ulcerative diseases of the cavity require observation not only by dentists, but also by pediatricians, family doctors and gastroenterologists.
The Mechanism for Forming Accessible Environment in Railway Transport
Authors: Rykova L.
Published: January 2023

The formation of an accessible environment that allows people with disabilities to exercise their rights in all spheres of public life is one of the priorities of the state policy of the Russian Federation in the field of disability. Effective social integration of disabled people is impossible without accessible passenger transport. In the passenger complex of Russian Railways, systemic measures are being taken to create a barrier-free environment in railway transport for people with limited mobility of consumers of transport services. However, to date, there is no description of the mechanism for the formation of an accessible environment in relation to railway transport, despite the fact that certain aspects of this process are widely considered in various sources.
Using Simulation Modeling to Determine Optimum Operating Modes of Traffic Lights at Investigated Crossroads
Authors: Sharsheeva K. , Tultemirova G. , Alymkulova M. , Ismanov Yu. , Alymkulov S. , Zhumaliev K.
Published: January 2023

The problem of traffic regulation has been a big problem in many countries for many years. One of the most acceptable methods of decoupling the traffic flow is to optimize the operation of the traffic light. This article presents a simulation method used to find the optimal modes of operation of a traffic light at a given intersection. Models were created that simulate the transport networks of the city, on the basis of which the experimental results of this simulation were obtained. The simulation was carried out on the basis of optimizing the time of the traffic light on the given sections of the routes. To optimize the operation of traffic lights, the following sequence of operations was implemented: during the iteration, optimization parameters were selected from those specified in the database, followed by work on the model based on these parameters; at the end of one cycle of the model, the value of the optimizing function was determined at the time of the cycle completion. The resulting optimizing function is analyzed and, if necessary, new values of the optimization parameters are introduced, a new value of the optimization function is found, and the process is repeated until the function satisfies the specified initial conditions or reaches a constant value. The data obtained as a result of the optimization showed that the optimization made it possible to increase the capacity of busy intersections by almost three times.
The War for Talents as a Competitive Strategy in Modern Organizations
Authors: Gorokhova V. , Kakadiy I.
Published: January 2023

The article examines the phenomenon of the War for Talents, as well as the importance of hiring and retaining talented employees in modern organizations. The War for Talents is a key competitive strategy at the moment, this article discusses the actions by which the company will be able to effectively use this strategy. Leading positions in the market are occupied by companies that improve working conditions, conduct an active analysis of personnel in the market and are ready to offer the most favorable conditions for work. An employee with high skills in a certain field, in modern socio-economic conditions, plays an important role in the success of the manager and the company as a whole. The purpose of the work is to study the main approaches to retaining talented employees in organizations.
International Regulations Governing the Situation Women Sentenced to Imprisonment and Women With Young Children
Authors: Minster M.
Published: January 2023

The need to study international standards and the practice of their implementation is due to the existing contradiction not only of the actual state of penitentiary systems, but also of penal enforcement policy, reflected in the expected results, both in Russia and abroad. Based on the analysis of international standards and established practice, the absence of international norms that would clearly express themselves regarding the situation of a mother imprisoned with a child has been revealed, in connection with which more complex issues arise, and practice in many countries is contradictory. In addition, international provisions, for example, the UN Standard Minimum Rules, do not specify: the special needs of women, pregnant women and convicted mothers with young children as a special category of convicts; the responsibility of the state to provide special protection to the child and provide care and assistance for his well-being; the age of children living in places of deprivation of liberty, etc. Numerous problems demonstrate the need for further research of penitentiary standards and rules for the possibility of their implementation in the world practice of execution of punishment.
To the Some Issues on Differentiation of Group Robbery From Banditry
Authors: Volchok I.
Published: January 2023

Author examines the actual problems that arise in practice in the qualification of robbery attacks, namely, the delimitation of a robbery attack from related offenses. The author places at the forefront the problem of delimiting a group armed robbery from banditry, due to the fact that in practice there are quite a few problems when delimiting these two trains and due to the fact that this problem remains relevant today. Based on the studied scientific materials, law enforcement and investigative practice, conclusions are drawn about the existence of problems of distinguishing between group armed robbery and banditry, a description and analysis of problematic issues is given, and information is given on how these problems are overcome by the law enforcement officer in practice, excerpts from the judicial practice of higher judicial authorities of the Russian Federation. The author cites the opinions of various experts in the field of criminal law on controversial issues, and also expresses his personal point of view on these problems and suggests ways to solve them.
Establishment of the Kyrgyz Parliament During the Period of Declared Sovereignty
Authors: Kulalieva G.
Published: January 2023

The Democracy and Parliamentarism concepts, which have become the basis of social development in Kyrgyzstan, did not emerge by chance and did not settle in an empty place. Since ancient times, the social structure of the Kyrgyz has been characterized by signs of popular democracy and parliamentarianism. At all times, representative bodies of power played an important role in political life of people. The highest institutions of power, making key decisions, were national kurultais. At crucial moments in history, it was they who made decisions that determined the future of Kyrgyz statehood. Today’s parliamentary democracy has its origins in the people’s kurultais. Through a long and rich history, our ancestors succeeded in preserving and passing down to the next generations the sacred values of freedom.
Legalization of Mining in Russia as a Counteraction to the Financing of Terrorism
Authors: Okuneva A.
Published: January 2023

The active use of cryptocurrency in financial transactions, on the one hand, simplifies this process, and on the other hand, creates certain risks. The relevance of the problem is dictated by the lack of legislative regulation in the Russian Federation of the economic turnover of cryptocurrencies and the use of crypto technologies in the credit and financial system. The problem is exacerbated by the fact that, along with the advent of the new currency, criminal threats to the economic security of the country associated with the financing of terrorism arose.
Pedagogical Conditions as Important Conditions for Overcoming the Failure of Adolescent Student
Authors: Turukbaeva A.
Published: January 2023

Significant changes taking place in the socio-economic life of the republic are reflected in the activities of the school, which is also forced and must change in order to meet the growing demands of society, the state and parents to improve the quality of education. Undoubtedly, the school understands what difficult, but feasible tasks it has to implement, and makes every effort to develop new curricula, programs, methods that contribute to the improvement of the educational process. Proceeding from this, in the research work, the author cited pedagogical conditions for overcoming the underachievement of adolescent schoolchildren, as well as the professional growth of teachers. With the right creation of pedagogical conditions for each student, it is possible to reduce the failure of adolescent students to a minimum. Adolescents will have an interest in learning, as well as a desire to overcome academic failure. For the optimal interaction of the subjects of the educational process, it is proposed to comply with five pedagogical conditions, the main leitmotif of which is to increase the social and cognitive self-esteem of adolescents and provide motivation to study subjects of the natural and mathematical cycle.
Assessment of the Level of Development of Natural Science Literacy of Secondary School Pupils of Mirny Settlement of Krasnoyarsk District of Samara Region
Authors: Taimasova E. , Yaitsky A.
Published: January 2023

At the present stage, federal state educational standards of general education attach special importance to the formation and development of functional literacy of pupils, which includes such components as natural science literacy, mathematical literacy, reading literacy, financial literacy, global competencies, creative thinking. Considerable attention is paid to the formation and development of functional literacy for the reason that the acquired knowledge, formed skills and abilities can be applied by pupils to solve life problems. This article is devoted to the development of natural science literacy of pupils in the lessons of the module “Fundamentals of natural science literacy” of the course “Fundamentals of functional literacy of basic school pupils» (on the example of a secondary school in the Mirny settlement, Krasnoyarsk District, Samara Region). The results of the pupils’ performance of a complex task on the topic “Living nature. Herbicides and their role”, which consisted of tasks of various types, such as working with text, working with a histogram and its analysis; analysis of graphic sources of information; a task with a choice of statements; working with a geographical map; working with text and reasoning conclusions. It was revealed that the majority of pupils (91%) have the ability to work with a geographical map, and the least well-formed pupils have the ability to analyze graphic sources of information. The results of the study showed that the majority of pupils have an average (47% of pupils) level of development of natural science literacy; an increased level was recorded in 19% of pupils; high and low levels were demonstrated by 13% of pupils, and 7% of pupils demonstrated insufficient natural science literacy.
Approaches to the Posthuman in a Polycentric Space
Authors: Khabibullina Z.
Published: January 2023

In article the critical analysis of the main treatments of the posthuman concept is carried out. The 21st century is marked by a contradictory understanding of the role and status of the human. The development of digitalization, started formation of a qualitatively new sphere, creates new opportunities, new realities (in particular, today it is — virtualization world, its nano- and biotechnologization etc.). Transhumanist projects aim to strengthen human influence by transforming human beings into other, more powerful and viable forms of being.
Gastroenterit Etkeni Virüslerin İmmünokromatografik Yöntem ve Multipleks PZR Yöntemiyle Araştırılması
Authors: TOPÇU Mücahide , KÖROĞLU Mehmet , AYDEMİR Özlem , AYDEMİR Yusuf , ALTINDİŞ Mustafa , ELMAS Bahri
Published: January 2023

Amaç: Akut gastroenterit (AGE), erken ve doğru tedavi edilmediğinde özellikle çocuklarda yüksek morbidite ve mortalite ile seyredebilen ve tüm dünyada sık görülen bir enfeksiyondur. Çocukluk döneminde en sık Rotavirüsler, Adenovirüsler, Norovirüsler AGE’lere neden olmaktadır. Viral enfeksiyonların hızlı tanısında, immünokromatografik (ICT) veya ELISA temelli yöntemler tercih edilmekte iken, son yıllarda multipleks polimeraz zincir reaksiyonu (PZR) testleri de laboratuvarlarda kullanılmaya başlanmıştır. Bu çalışmada Rotavirus, Adenovirus ve Norovirus tanısında immünokromatografik yöntem ve PZR yöntemi ile elde edilen sonuçların karşılaştırılması amaçlanmıştır.
Gereç ve Yöntemler: Çalışmaya AGE tanılı hastaların ICT yöntemi ile Rotavirus ve/veya Adenovirus pozitif olarak saptanan 67 gaita örneği ve ICT yöntemi ile viral, bakteriyel, paraziter etkenler açısından negatif bulunan 17 gaita örneği dâhil edildi. Bu örneklerde Rotavirus, Norovirus RNA’sı ile Adenovirus DNA’sı multipleks PZR kiti kullanılarak araştırıldı.
Bulgular: ICT yöntemi ile örneklerin 62’sinde (%73,8) Rotavirus pozitif iken, gerçek zamanlı PZR yöntemi ile 49’unda (%58,5) Rotavirus pozitif bulundu. ICT yöntemi ile örneklerin beşinde (%5,9) Adenovirus pozitif bulunurken, multipleks gerçek zamanlı PZR yöntemi ile 40’ında (%47,6) Adenovirus pozitif tespit edildi. Örneklerin 11’inde (%13) Norovirus pozitif saptandı.
Sonuç: En sık karşılaşılan viral gastroenterit etkenleri olan Rotavirus ve Adenovirus tanısı için çok yaygın olarak ICT kullanılmaktadır. Ancak çalışmamızda da görüldüğü üzere; bu tür olgularda Norovirüs gibi diğer gastroenterit etkeni virüslerin de klinik tablodan sorumlu olabileceği göz ardı edilmemelidir. Rotavirus ve Adenovirus tanımlamasında ICT ve PZR yöntemleri arasında anlamlı ancak düşük düzeyde korelasyon saptandı.
Is There a Relationship Between Perceived Activity Performance-Satisfaction Level and Quality of Life in Activities of Daily Living in Adults with Plantar Fasciitis?
Authors: TORPİL Berkan , GÜNEY YILMAZ Güleser , ÖNAL Gözde , KAYA Özgür
Published: January 2023

Aim: Plantar fasciitis (PF) is a disease that negatively affects quality of life (QOL) and activities of daily living and is the most common cause of heel pain. The aim of this study is to examine the relationship between QOL, perceived activity performance and satisfaction in adults with PF and to determine the activities that have problems in daily living.

Materials and Methods: A total of 96 participants, 26 male and 70 female, aged between 18-65 years, with a mean age of 53.88±6.41 years diagnosed with PF completed the study. The Nottingham Health Profile was used to determine the QOL, the Canadian Occupational Performance Measure was used to determine the perceived activity performance and satisfaction level.

Results: The findings show the perceived activity performance and satisfaction levels of individuals with PF are negatively related to pain and energy levels, which are sub-dimensions of QOL (p=0.001; p=0.017; p=0.001; p=0.018). Moreover, it has been determined individuals have problems in many activities, such as walking, working, going up and down stairs, housecleaning and sleeping.

Conclusion: This study showed the QOL of individuals with PF decreases as activity performance and satisfaction level decrease. Pain is one of the most important factors affecting activity performance, and recurrent and increasing pain with activity may have limited activity participation in individuals with PF. Therefore, pain should be considered as a priority in the evaluation and intervention plans of individuals with PF. Also, activity-based intervention plans should be developed for activities where these individuals have problems in daily living.
Abiraterone and Docetaxel Treatments Increase Phospho-PTEN Expression in Metastatic Prostate Cancer Cells
Authors: SOYLU Hakan , AKSU Kübra , ÜSTÜNEL İsmail , KARACOR Kayihan , BEYAZÇİÇEK Özge
Published: January 2023

Aim: Prostate cancer is the second leading cause of death in cancer-related deaths in men. Docetaxel and abiraterone acetate are widely used in the treatment of castration-resistant metastatic prostate cancer. Phospho-PTEN triggers proliferation, migration, angiogenesis and survival in cells by causing oncogenic Akt hyperactivation. This study, it is aimed to investigate the effects of docetaxel and abiraterone acetate agents, which are widely used in the treatment of prostate cancer, on the expression of phospho-PTEN, which stimulates the oncogenic pathway.
Material and Methods: The effects of docetaxel and abiraterone acetate on phospho-PTEN expression in androgen receptor (+) and androgen receptor (-) metastatic prostate cancer cell lines were investigated in vitro by immunofluorescence method.
Results: Findings were compatible in both androgen receptor (+) and androgen receptor (-) metastatic prostate cancer cell lines. No statistically significant difference in phospho-PTEN expression was observed between the control and abiraterone acetate groups. Phospho-PTEN expression was increased statistically significant in docetaxel and abiraterone acetate+docetaxel groups compared to control. This increase was greater statistically significant in the combined group given the two agents compared to the docetaxel group.
Conclusion: A significant increase in phospho-PTEN was observed in the docetaxel and combined treatment groups. The increase of Phospho-PTEN causes oncogenic Akt hyperactivation. According to this information, docetaxel and combined drug treatments may support the oncogenic pathway in cells by increasing phospho-PTEN in patients. To eliminate these effects in patients, the administration of agents that dephosphorylate PTEN or agents that will stimulate the pathways that provide dephosphorylation may increase the total survival of the patients.
Pansinusitis, complicated by extensive osteonecrosis of the upper jaw and secondary rhinogenic intracerebral abscess of the right fronto-parietal region of the brain after a COVID-19 (clinical case)
Authors: Podolsky V. V. , Yarygina E. N. , Kirpichnikov M. V. , Khimich I. V. , Serbin A. S. , Mukhaev Kh. Kh. , Efimova E. V. , Aleshanov K. A.
Published: January 2023

The number of complications of new coronavirus infection (COVID-19) has been growing in clinics of maxillofacial surgery and otorhinolaryngology in the past two years. Among them, lesions of the jaw bones, nasal bones and paranasal sinuses are predominate. As a result of the studies, it was found that with coronavirus infection, multiple microvascular and macrovascular disorders occur, resulting in necrosis of the jaws and paranasal sinuses, often leading to life-threatening conditions, due to the anatomical proximity of brain structures. The article presents a cli-nical observation of a patient with extensive osteonecrosis of the upper jaw, which developed against the background of postcovid purulent pasinusitis, complicated by a secondary rhinogenic intracerebral abscess of the right fronto-parietal region of the brain. The provoking factors, the most characteristic symptoms, the X-ray picture at different stages of the disease, the tactics of treating such complications are considered.