bluuebunny/crossref_metadata_2025 huggingface dataset:
Conference & Planning Committee Information
Authors: Lukes Laura
Published: August 2016

Theme:The Science of Learning: Using Research to Improve Teaching7th Annual ConferenceSeptember 18, 2015 Conference Director:Laura Lukes (Center for Teaching & Faculty Excellence) Advisory & Selection Committee: Boicu, MihaiBoyette, JoannaClare, KatieCressman, RobEby, KimEdwards, CodyGeorge, ChristianGliozzi, MarioGoldman, JonathanHannan, HeatherKoch, LisaKravitz, DavidLawrence, SusanLukes, LauraMallett, KarynOffutt, JeffOlesova, LarisaOwen, JuliePettigrew, KathyReid, ShelleyRogers, PaulSaleem, RajaSaunders, CathyScott Constantine, LynneUsher, BethanyWarren, JohnWest, PatriciaWillis, OdetteWolf, PaigeYigit, Erdal Logistical Coordination:Ashleen Gayda (Center for Teaching & Faculty Excellence)Tamara Day (Events Management) Logistical Support:Office of Events ManagementEvents ProductionMason CateringAndrew Cote (OSCAR)Samira Lloyd (OSCAR)Denise Nazaire (OSCAR) Conference Proceedings:John WarrenJeri WieringaLaura LukesAshleen GaydaEmily LambackChyna Staten (Retroactive)                               Sponsors: BlackboardGeorge Mason University LibrariesGeorge Mason Publishing GroupProQuestUPCEABarnes & Noble College: George Mason Bookstore4-VAThe New York Times in Education Supporters:College of Education and Human Development; College of Health and Human Services; College of Humanities and Social Sciences; College of Science; College of Visual and Performing Arts; Graduate Student Life; Higher Education Program; Information Technology Services; Office of Distance Education; Office of Student Scholarship, Creative Activities, and Research; School for Conflict Analysis and Resolution; School of Business; School of Policy, Government, and International A airs; University Life; Volgenau School of Engineering; Writing Across the Curriculum; and The Writing Center.Volunteers:Dorothy Amoah-Darko, Sam Ashworth, Jesse Capobianco, Cameron Carter, Andrew Cartwright, Zella Christensen, Lynne Scott Constantine, Svetlana Filiatreau, Andrew Finn, Darcy Gagnon, Liesel Hamilton, Caitlin Holmes, Tabine Kamaleddine, Mills Kelly, Joey Kuhn, Ying-Ying Kuo, Shawn Lee, Jaime Lester, Jessica Matthews, Je O utt, Larisa Olesova, Julie Owen, Nathalia Peixoto, Richena Purnell-Sayle, Esperanza Roman-Mendoza, Robert Sachs, Catherine Saunders, Linda Sheridan, Darlene Smucny, Debra Sprague, Carol Stiller, Bethany Usher, John Warren, Gerald Weatherspoon, Margaret Weiss, and the students of TOUR 440.  of Engineering; Writing Across the Curriculum; and The Writing Center.
The (Not-So) Secrets to Successful Research- and Scholarship-Intensive Courses
Authors: Usher Bethany
Published: August 2016

The Students as Scholars initiative encourages faculty and programs to approach teaching research from a developmental and scaffolded perspective. Students are introduced to scholarship in Discovery courses, acquire disciplinary skills in Inquiry courses, and take responsibility for carrying out a scholarly project in Research and Scholarship (RS)-intensive courses.Using OSCAR materials and information from three years of successful RS courses, this poster will demonstrate:Features of RS coursesThe process of applying for an RS designationHow to use a curriculum map to plan their courseDeveloping research assignments beyond the "research paper"Models for incorporating RS (and other Students as Scholars) courses into program curriculaFaculty (from all schools and disciplines) who are poised to apply for RS designation, instructors who are exploring the possibility, professors who want to understand what students are doing in RS courses, and program coordinators who want to see how to incorporate RS courses are all invited to visit this poster.
Creating inclusive learning environments: Strategies from performance based assessments in a graduate linguistics course
Authors: Wong Shelly , Shin Hye Young , Tu Thuy Thi-Minh
Published: August 2016

This poster discusses an action research project to improve performance based assessments for two assignments in a graduate linguistics for teachers course.  EDCI 510 - Linguistics for Teachers is a required course for graduate students in the M. Ed program for Kindergarten to Grade 12 English to Speakers of Other Languages (ESOL ) for teacher licensure approved by the Virginia State Department of Education.  In the course, there are two performance based assessment (PBA) assignments: a textbook analysis and a lesson plan.  The paper describes the use of critical discourse analysis (CDA) and critical race theory (CRT)  to analyze exemplary student assignments and to modify course descriptions of the assignments and the rubrics to support 1) critical examination of text book bias in social studies, math and science textbooks, 2) lesson plans that support teaching linguistically and culturally diverse students especially those who have had interrupted schooling 3) creative use of technology for more inclusive, culturally responsive and socially just classroom practices.  Participants will gain insights about framing and designing assignments and rubrics to support student learning, while also creating an inclusive learning environment.
The role of GαO‐mediated signaling in the rostral ventrolateral medulla oblongata in cardiovascular reflexes and control of cardiac ventricular excitability
Authors: Ang Richard , Abramowitz Joel , Birnbaumer Lutz , Gourine Alexander V. , Tinker Andrew
Published: August 2016

The heart is controlled by the sympathetic and parasympathetic limbs of the autonomic nervous system with inhibitory signaling mechanisms recruited in both limbs. The aim of this study was to determine the role of inhibitory heterotrimeric G proteins in the central nervous mechanisms underlying autonomic control of the heart and its potential role in arrhythmogenesis. Mice with conditional deletion of the inhibitory heterotrimeric G protein GαO in the presympathetic area of the rostral ventral lateral medulla (RVLM) were generated to determine the role of GαO‐mediated signalling in autonomic control and electrophysiological properties of the heart. GαO deletion within the RVLM was not associated with changes in heart rate (HR) or the arterial blood pressure at rest (home cage, normal behavior). However, exposure to stressful conditions (novel environment, hypoxia, or hypercapnia) in these mice was associated with abnormal HR responses and an increased baroreflex gain when assessed under urethane anesthesia. This was associated with shortening of the ventricular effective refractory period. This phenotype was reversed by systemic beta‐adrenoceptor blockade, suggesting that GαO depletion in the RVLM increases central sympathetic drive. The data obtained support the hypothesis that GαO‐mediated signaling within the presympathetic circuits of the RVLM contributes to the autonomic control of the heart. GαO deficiency in the RVLM has a significant impact on cardiovascular responses to stress, cardiovascular reflexes and electrical properties of the heart.
Stress hardening under long-term cadmium treatment is correlated with the activation of antioxidative defence and iron acquisition of chloroplasts in Populus
Authors: Solti Ádám , Sárvári Éva , Szöllősi Erzsébet , Tóth Brigitta , Mészáros Ilona , Fodor Ferenc , Szigeti Zoltán
Published: August 2016

Cadmium (Cd), a highly toxic heavy metal affects growth and metabolic pathways in plants, including photosynthesis. Though Cd is a transition metal with no redox capacity, it generates reactive oxygen species (ROS) indirectly and causes oxidative stress. Nevertheless, the mechanisms involved in long-term Cd tolerance of poplar, candidate for Cd phytoremediation, are not well known. Hydroponically cultured poplar (Populus jacquemontiana var. glauca cv. ‘Kopeczkii’) plants were treated with 10 μM Cd for 4 weeks. Following a period of functional decline, the plants performed acclimation to the Cd induced oxidative stress as indicated by the decreased leaf malondialdehyde (MDA) content and the recovery of most photosynthetic parameters. The increased activity of peroxidases (PODs) could have a great impact on the elimination of hydrogen peroxide, and thus the recovery of photosynthesis, while the function of superoxide dismutase (SOD) isoforms seemed to be less important. Re-distribution of the iron content of leaf mesophyll cells into the chloroplasts contributed to the biosynthesis of the photosynthetic apparatus and some antioxidative enzymes. The delayed increase in photosynthetic activity in relation to the decline in the level of lipid peroxidation indicates that elimination of oxidative stress damage by acclimation mechanisms is required for the restoration of the photosynthetic apparatus during long-term Cd treatment.
Jesus, the Isaianic Servant Exorcist Exploring the Significance of Matthew 12,18–21 in the Beelzebul Pericope
Authors: Nickel J.P.
Published: August 2016

In der Auseinandersetzung mit dem Zitat aus Jes 42,1–4 in Mt 12,18–21 wurde die kontextuelle Bedeutung der matthäischen Beelzebulkontroverse in 12,22–30 nicht ausreichend berücksichtigt. Dieser Beitrag möchte diese Lücke füllen. Der erste Abschnitt umreißt die Hauptprobleme, die sich mit der Auslegung des matthäischen Zitats aus dem Jesajabuch verbinden. Vor diesem Hintergrund wird im zweiten Abschnitt aufgewiesen, dass Matthäus gezielt Änderungen an seinen Quellen vorgenommen hat, um die Identifikation Jesu als jesajanischer Gottesknecht mit der Diskussion über die eschatologische Bedeutung seiner geistgewirkten Exorzismen zu verbinden. Im dritten Abschnitt wird daraufhin die Deutung vorgeschlagen, dass Matthäus mithilfe dieser lexikalischen Verknüpfungen eine einzigartige Verbindung zwischen der Aufgabe des jesajanischen Gottesknechts und der eschatologischen Niederlage Satans herstellt, die, wie 12,22–30 verdeutlicht, in Jesu Exorzismen dargestellt wurde.
Die Witwe, das γαζοφυλάκιον und der Tempel. Beobachtungen zur mk Erzählung vom „Scherflein der Witwe“ (Mk 12,41–44)
Authors: Lau Markus
Published: August 2016

Despite the many different interpretations of Mk 12,41–44, they all seem to be based on the consensus that different types of donations are described. It is also this understanding that defines the noun γαζοφυλάκιον as offertory box. This common understanding is here challenged. By engaging texts from the LXX and Josephus, the article discloses another reality of the temple of Jerusalem: The temple was also a place for safekeeping money that remained in the possession of the person who brought it there and deposited it in the γαζοφυλάκιον. Thus, Mk 12,41–44 does not tell of persons who are generous to varying degrees, but is instead a story of bank deposits. This reading is then interpreted in light of the gospel of Mark more broadly.
A case of pituitary abscess presenting without a source of infection or prior pituitary pathology
Authors: Adams Derick , Kern Philip A
Published: August 2016

Pituitary abscess is a relatively uncommon cause of pituitary hormone deficiencies and/or a suprasellar mass. Risk factors for pituitary abscess include prior surgery, irradiation and/or pathology of the suprasellar region as well as underlying infections. We present the case of a 22-year-old female presenting with a spontaneous pituitary abscess in the absence of risk factors described previously. Her initial presentation included headache, bitemporal hemianopia, polyuria, polydipsia and amenorrhoea. Magnetic resonance imaging (MRI) of her pituitary showed a suprasellar mass. As the patient did not have any risk factors for pituitary abscess or symptoms of infection, the diagnosis was not suspected preoperatively. She underwent transsphenoidal resection and purulent material was seen intraoperatively. Culture of the surgical specimen showed two species of alpha hemolytic Streptococcus, Staphylococcus capitis and Prevotella melaninogenica. Urine and blood cultures, dental radiographs and transthoracic echocardiogram failed to show any source of infection that could have caused the pituitary abscess. The patient was treated with 6weeks of oral metronidazole and intravenous vancomycin. After 6weeks of transsphenoidal resection and just after completion of antibiotic therapy, her headache and bitemporal hemianopsia resolved. However, nocturia and polydipsia from central diabetes insipidus and amenorrhoea from hypogonadotrophic hypogonadism persisted.

Learning points

Pituitary abscesses typically develop in patients who have other sources of infection or disruption of the normal suprasellar anatomy by either surgery, irradiation or pre-existing pathology; however, they can develop in the absence of known risk factors.

Patients with pituitary abscesses typically complain of headache, visual changes and symptoms of pituitary hormone deficiencies.

As other pituitary neoplasms present with similar clinical findings, the diagnosis of pituitary abscess is often not suspected until transsphenoidal resection is performed.

Prompt surgical and medical treatment of pituitary abscess is necessary, which typically results in improvement in headache and visual changes; however, pituitary hormone deficiencies are typically often permanent.
Germline mutations and genotype–phenotype correlation in Asian Indian patients with pheochromocytoma and paraganglioma
Authors: Pandit Reshma , Khadilkar Kranti , Sarathi Vijaya , Kasaliwal Rajeev , Goroshi Manjunath , Khare Shruti , Nair Sandhya , Raghavan Vijaya , Dalvi Abhay , Hira Priya , Fernandes Gwendolyn , Sathe Pragati , Rojekar Amey , Malhotra Gaurav , Bakshi Ganesh , Prakash Gagan , Bhansali Anil , Walia Rama , Kamalanathan Sadishkumar , Sahoo Jayaprakash , Desai Ankush , Bhagwat Nikhil , Mappa Prashanth , Rajput Rajesh , Chandrashekhar Sudha Rao , Shivane Vyankatesh , Menon Padma , Lila Anurag , Bandgar Tushar , Shah Nalini
Published: August 2016

Background

Genetic aetiology of pheochromocytoma (PCC) and paraganglioma (PGL) is increasingly being studied; however, Asian Indian data on this aspect are scarce.

Objective

To study the prevalence of germline mutations and genotype–phenotype correlation in Asian Indian PCC/PGL patients.

Design

In this study, 150 index patients (M:F, 73:77) with PCC/PGL were evaluated. Phenotypic data were collected. Germline mutations in five susceptibility genes (RET, VHL, SDHB, SDHD and SDHC) were tested by sequencing and NF1 was diagnosed according to phenotype.

Result

Of the total population, 49 (32.7%) PCC/PGL patients had germline mutations (VHL: 23 (15.3%), RET: 13 (8.7%), SDHB: 9 (6%), SDHD: 2 (1.3%) and NF1: 2 (1.3%)). Amongst the 30 patients with familial and/or syndromic presentation, all had germline mutations (VHL: 14 (46.7%), RET: 13 (43.3%), SDHB: 1 (3.3%) and NF1: 2 (6.7%)). Out of 120 patients with apparently sporadic presentation, 19 (15.8%) had a germline mutation (VHL: 9 (7.5%), SDHB: 8 (6.7%) and SDHD: 2 (1.7%)). Mutation carriers were younger (29.9 ± 14.5 years vs 36.8 ± 14.9; P = 0.01) and had a higher prevalence of bilateral PCC (26.5% vs 2.9%, P < 0.001) and multifocal tumours (12.2% vs 0.96%, P = 0.06). Based on syndromic features, metastasis, location and number of tumours, around 96% mutations in our cohort could be detected by appropriately selected single gene testing.

Conclusion

Asian Indians with PCC/PGL differ from Western cohorts in having preponderance of VHL mutations in multifocal tumours and apparently sporadic unilateral PCC. Syndromic presentation, metastasis, location and number of PCC/PGL can be effectively used for guiding genetic prioritisation.
Nicotinamide Suppresses the DNA Damage Sensitivity of Saccharomyces cerevisiae Independently of Sirtuin Deacetylases
Authors: Rössl Anthony , Bentley-DeSousa Amanda , Tseng Yi-Chieh , Nwosu Christine , Downey Michael
Published: August 2016

Nicotinamide is both a reaction product and an inhibitor of the conserved sirtuin family of deacetylases, which have been implicated in a broad range of cellular functions in eukaryotes from yeast to humans. Phenotypes observed following treatment with nicotinamide are most often assumed to stem from inhibition of one or more of these enzymes. Here, we used this small molecule to inhibit multiple sirtuins at once during treatment with DNA damaging agents in the Saccharomyces cerevisiae model system. Since sirtuins have been previously implicated in the DNA damage response, we were surprised to observe that nicotinamide actually increased the survival of yeast cells exposed to the DNA damage agent MMS. Remarkably, we found that enhanced resistance to MMS in the presence of nicotinamide was independent of all five yeast sirtuins. Enhanced resistance was also independent of the nicotinamide salvage pathway, which uses nicotinamide as a substrate to generate NAD+, and of a DNA damage-induced increase in the salvage enzyme Pnc1. Our data suggest a novel and unexpected function for nicotinamide that has broad implications for its use in the study of sirtuin biology across model systems.
Classification, Electrophysiological Features and Therapy of Atrioventricular Nodal Reentrant Tachycardia
Authors: Katritsis Demosthenes G ,   Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA, Josephson Mark E ,   Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Published: August 2016

Atrioventricular nodal reentrant tachycardia (AVNRT) should be classified as typical or atypical. The term ‘fast-slow AVNRT’ is rather misleading. Retrograde atrial activation during tachycardia should not be relied upon as a diagnostic criterion. Both typical and atypical atrioventricular nodal reentrant tachycardia are compatible with varying retrograde atrial activation patterns. Attempts at establishing the presence of a ‘lower common pathway’ are probably of no practical significance. When the diagnosis of AVNRT is established, ablation should be only directed towards the anatomic position of the slow pathway. If right septal attempts are unsuccessful, the left septal side should be tried. Ablation targeting earliest atrial activation sites during typical atrioventricular nodal reentrant tachycardia or the fast pathway in general for any kind of typical or atypical atrioventricular nodal reentrant tachycardia, are not justified. In this review we discuss current concepts about the tachycardia circuit, electrophysiologic diagnosis, and ablation of this arrhythmia.
Plasmid-mediated quinolone resistance among extended spectrum beta lactase producing Enterobacteriaceae from bloodstream infections
Authors: Domokos Judit , Kristóf Katalin , Szabó Dóra
Published: August 2016

The purpose of this study was to determine prevalence and molecular characterization of plasmid-mediated quinolone resistance (PMQR) genes [qnrA, qnrB, qnrC, qnrD, qnrS, aac(6′)-Ib-cr, qepA, and oqxAB] among extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella spp. isolates from bloodcultures in Hungary. A total of 103 isolates were tested for quinolone susceptibility by microdilution method and PMQR genes were detected by polymerase chain reaction. About 40 ESBL-producing E. coli (39%) and 50 ESBL-producing Klebsiella spp. strains (48%) were resistant to ciprofloxacin; 40 ESBL-producing E. coli (39%) and 47 ESBL-producing Klebsiella spp. strains (45%) were resistant to levofloxacin; and 88 strains including 40 ESBL-producing E. coli (39%) and 48 (47%) ESBL-producing Klebsiella spp. were resistant to moxifloxacin. Among the 103 ESBL-producing isolates, 77 (75%) isolates (30 E. coli and 47 Klebsiella spp.) harbored PMQR genes. The most commonly detected gene was aac(6′)-Ib-cr (65%). The occurrence of qnrS gene was 6%. Interestingly, qnrA, qnrB, qnrC, qnrD, and qepA were not found in any isolates. Among 77 PMQR-positive isolates, 27 (35.1%) and 1 (1.3%) carried two and three different PMQR genes, respectively. Only Klebsiella spp. harbored more than one PMQR genes. Observing prevalence of PMQR genes in the last 8 years, the increasing incidence of aac(6′)-Ib-cr and oqxAB can be seen. Our results highlight high frequency of PMQR genes among ESBL-producing Klebsiella pneumoniae and E. coli isolates with an increasing dynamics in Hungary.
Ebola virus disease: Awareness among dental students in Hungary
Authors: Károlyházy Katalin , Fazekas Balázs , Fazekas Janka , Hermann Péter , Márton Krisztina
Published: August 2016

Introduction:

The Ebola epidemic has claimed thousands of lives in Africa, and there has been a mounting pressure on the healthcare systems around the globe to prepare for the showing up of patients infected with this virus. Junior clinicians are at the forefront of medical teams, often coming into contact with patients first, during clerking and admissions. This study assesses the level of knowledge of Ebola virus disease (EVD) among dental students at Semmelweis University, Budapest, Hungary.

Materials and methods:

A cross-sectional survey of 257 dental students was carried out across five different courses. Each of the students was asked to fill out a detailed questionnaire comprising of 11 questions, to assess their knowledge about signs and symptoms, investigations, management, and sequelae of the virus and the outbreak.

Findings:

This study highlighted that there is an overall lack of knowledge about critical aspects of EVD among dental students. We found that the participating students scored less than 60% for 8 of the 11 questions, including those assessing their recognition and subsequent management of EVD.

Conclusion:

These results are concerning and the medical universities and dental schools need to act fast to prepare the Hungary’s dental (and medical) students and junior doctors for an inevitable influx of infected patients.
PRIEŠIRDŽIŲ VIRPĖJIMU SERGANČIŲ PACIENTŲ SU SVEIKATA SUSIJUSI GYVENIMO KOKYBĖ TIRIANT LIGAI SPECIFINIU AF-QoL KLAUSIMYNU
Authors: Karpavičienė Vaiva , Kalibatienė Danutė
Published: August 2016

Reikšminiai žodžiai: prieširdžių virpėjimas, gyvenimo kokybė, ligai specifinis AF-QoL klausimynas. Darbo tikslas. Įvertinti prieširdžių virpėjimu sergančių pacientų su sveikata susijusią gyvenimo kokybę naudojant ligai specifinį klausimyną. Darbo uždaviniai. Įvertinti sergančiųjų prieširdžių virpėjimu su sveikata susijusią gyvenimo kokybę atsižvelgiant į sociodemografinius veiksnius: lytį, amžių, išsilavinimą, pajamas, šeiminę padėtį, ir klinikinius požymius: prieširdžių virpėjimo trukmę, tipą, EHRA (Europos širdies ritmo asociacijos) nustatytas simptomų klases, gretutines ligas. Tyrimo medžiaga ir metodai. Darbas atliktas Vilniaus miesto klinikinės ligoninės Vidaus ligų klinikos skyriuose. Tiriamųjų atranka tikslinė. Tyrime dalyvavo 229 prieširdžių virpėjimu sergantys pacientai: 130 vyrų (56,8 proc.) ir 99 moterys (43,2 proc.), 50–70 m., amžiaus vidurkis 62,36 + 6,35 m. Tyrimui naudotas ligai specifinis su sveikata susijusios gyvenimo kokybės AF-QoL klausimynas. Duomenys buvo analizuojami statistiniu duomenų apdorojimo paketu SPSS („Statistical Package for Social Sciences“, SPSS Inc., 20 versija). Kokybinių duomenų skirtumams tarp atskirų respondentų grupių vertinti naudotas Chi kvadrato kriterijus (c2) su pasirinktu reikšmingumo lygmeniu p < 0,05. Vidurkių tarp dviejų nepriklausomų respondentų grupių skirtumams vertinti naudotas Stjudento t-kriterijus nepriklausomoms imtims ir jo neparametrinis analogas – Mann-Whitney kriterijus. Esant daugiau nei dviem respondentų grupėms, skirtumams tarp jų vertinti buvo naudojama neparametrinė statistika – Kruskal-Wallis ranginis kriterijus nepriklausomoms imtims. Darbo rezultatai ir išvados. Prieširdžių virpėjimu sergančių pacientų su sveikata susijusi gyvenimo kokybė tiriant AF-QoL klausimynu priklauso nuo lyties, šeiminės padėties, išsilavinimo ir pajamų. Gyvenimo kokybę geriau vertina vyrai nei moterys, taip pat respondentai, turintys nebaigtą aukštąjį ir aukštąjį išsilavinimą, gaunantys didesnes pajamas bei gyvenantys su sutuoktiniu. Gyvenimo kokybei turi įtakos prieširdžių virpėjimo trukmė (sergantys trumpiau nei 0,5 metų pateikia geresnius rezultatus) ir nedaug PV tipas (gyvenimo kokybė vertinama geriau tik tam tikrose srityse). Gyvenimo kokybę blogina širdies nepakankamumas ir krūtinės angina. Sergantys III NYHA funkcinės klasės širdies nepakankamumu pacientai gyvenimo kokybę vertina blogiau negu II NYHA funkcinės klasės pacientai. Stabilia krūtinės angina sergantys pacientai vertina blogiau psichologinę gyvenimo kokybę, tačiau tai neturi įtakos bendros gyvenimo kokybės vertinimui. Gyvenimo kokybės vertinimų skirtumų, priklausomai nuo EHRA simptomų klasės, nenustatyta.
KLINIKINIŲ IR RADIOLOGINIŲ SKALIŲ VERTĖ PROGNOZUOJANT ŪMINIO PANKREATITO EIGĄ IR KOMPLIKACIJAS. PERSPEKTYVINIO DAUGIACENTRIO KOHORTINIO TYRIMO REZULTATAI
Authors: Karpavičius Andrius , Dambrauskas Žilvinas , Samuilis Artūras , Gradauskas Audrius , Žvinienė Kristina , Brimas Gintautas , Činčikas Jonas , Mečkovski Artur , Šileikis Audrius , Strupas Kęstutis
Published: August 2016

Reikšminiai žodžiai: pankreatitas, prognozavimas, BISAP, CTSI, MCTSI. Darbo tikslas. Įvertinti klinikinių bei radiologinių skalių vertę, prognozuojant ŪP eigą, kasos nekrozę, intervencijų poreikį ir išeitis. Medžiaga ir metodai. Multicentrinė perspektyvinė studija buvo vykdoma keturiose Vilniaus ir Kauno gydymo įstaigose. Hospitalizuotų dėl ūminio pankreatito pacientų būklė 1-ąją hospitalizacijos parą įvertinta naudojant HAPS ir BISAP prognozines skales, apskaičiuojant surinktus balus. 3–7-ą susirgimo parą pacientams buvo atliekama pilvo organų kompiuterinė tomografija su intaveniniu kontrastavimu ir apskaičiuoti CTSI ir MCTSI skalių balai. Remiantis atnaujintu Atlantos sutarimu, visi pacientai buvo suskirstyti į tris grupes pagal ligos eigą: lengvo, vidutinio sunkumo ir sunkaus ūminio pankreatito. Klinikinių ir radiologinių skalių balai buvo lyginami tarp grupių, ir, braižant ROC kreives, nustatytos kritinės reikšmės, kuriomis remiantis galima prognozuoti sunkios eigos ūminį pankreatitą, kasos nekrozę, intervencijas bei išeitis. Rezultatai. Tyrime dalyvavo 102 ūminiu pankreatitu sirgę pacientai. Iš jų lengvu ūminiu pankreatitu sirgo 27 (26,5%), vidutinio sunkumo – 55 (53,9%) ir sunkiu – 20 (19,6%) asmenų. Nustatyta, jog BISAP (kritinė reikšmė ≥2), CTSI (kritinė reikšmė ≥6) bei MCTSI (kritinė reikšmė ≥8) skalės statistiškai patikimai atskiria sunkiu ūminiu pankreatitu sergančius pacientus nuo sergančių lengvesnėmis formomis. Kasos nekrozės kritinės prognozinės reikšmės yra ≥2 (BISAP), ≥3 (CTSI) ir ≥5 (MCTSI) balai. BISAP skalės kritinė prognozinė vertė intervencijoms yra ≥3 balai, CTSI – ≥5, o MCTSI – ≥8 balai; paciento mirtį atitinkamai prognozuoja – ≥4, ≥6 ir ≥8 balai. Išvados. BISAP prognozinė sistema yra gana tiksli, universali ir ankstyva prognozuojant SŪP, kasos nekrozę, intervencijas bei išeitis. Radiologinės skalės tinkamos ŪP eigai prognozuoti, tačiau yra per daug vėlyvos ir labiau naudingos gydymo taktikai parinkti.
Physical therapies in 19th century Aotearoa/New Zealand: Part 1 – Māori physical therapies
Authors: Nicholls David A. , Harwood Grayson , Bell Ricky
Published: August 2016

This paper is the first of three reporting on a historiographic study of physical therapies in 19th century Aotearoa/New Zealand. This first paper focuses on traditional Māori healing practices. The paper begins by setting out the parameters for the study and outlining the role that massage and manipulation, electrotherapy, hydrotherapy and remedial exercise played in societies around the world prior to the 20th century. We then explore traditional Māori physical therapies, focusing on two broadly ‘orthopaedic’ conditions (fractures and back pain), before examining accounts of two predominant forms of physical therapy: massage and the use of Aotearoa/New Zealand’s abundant thermal springs. We conclude the paper by examining the cultural shift that took place with colonisation after 1840, and consider the effect that this shift had on Māori physical therapy practices prior to 1900.
Effect of Heavy Smoking on Dental Implants Placed in Male Patients Posterior Mandibles: A Prospective Clinical Study
Authors: Sun Cong , Zhao Jinxiu , Jianghao Chen , Hong Tao
Published: August 2016

The objective of this study was to evaluate the implant stability and peri-implant tissue response in heavy smokers receiving dental implants due to partially edentulous posterior mandibles. Forty-five ITI Straumann dental implants were placed into the partially edentulous posterior mandibles of 16 heavy smokers and 16 nonsmokers. One implant in each patient was evaluated for implant stability after surgery and before loading, and for the modified plaque index (mPLI), modified sulcus bleeding index (mSBI), probing depth (PD), and marginal bone loss (MBL) after loading. Meanwhile, the osteogenic capability of jaw marrow samples collected from patients was evaluated via an in vitro mineralization test. For both groups, the implant stability quotient (ISQ) initially decreased from the initial ISQ achieved immediately after surgery and then increased starting from 2 weeks postsurgery. However, at 3, 4, 6, and 8 weeks postsurgery, the ISQ differed significantly between nonsmokers and heavy smokers. All implants achieved osseointegration without complications at least by the end of the 12th week postsurgery. At 6 or 12 months postloading, the MBL and PD were significantly higher in heavy smokers than in nonsmokers, whereas the mSBI and mPLI did not differ significantly between the 2 groups. The 1-year cumulative success rate of implants was 100% for both groups. Within the limitations of the present clinical study (such as small sample size and short study duration), which applied the loading at 3 months postoperation, heavy smoking did not affect the cumulative survival rate of dental implants placed at the posterior mandible in male patients, but heavy smoking did negatively affect bone healing around dental implants by decreasing the healing speed. These results implied that it might be of importance to select the right time point to apply the implant loading for heavy smokers. In addition, heavy smoking promoted the loss of marginal bone and the further development of dental pockets. Further clinical studies with larger patient populations are warranted to confirm our findings over a longer study duration.
Training Teachers with a Virtual Learning Community: Connecting Peers with an International Dimension
Authors: García Fernández Beatriz , Jiménez Antonio Mateos , Bejarano Franco María Teresa
Published: August 2016

Here we present research into the use of a virtual learning community in formal teacher training to determine the associated pedagogical benefits. The community was used by 876 teacher candidates, graduate teachers and university teachers from Spain, Chile and Belgium. Using it resulted in benefits relating to the transfer of knowledge and pedagogical experiences, cooperative and collaborative work, teacher coordination and contextual diversity, and it has been highly valued by the participants.
Associação entre sobrepeso e hipertensão arterial em crianças e adolescentes
Authors: Júnior Cláudio Sagrilo , Dos Reis Germano Ramos , Jaeger Diogo Bezzi , Siqueira Osvaldo Donizete , Crescente Luiz Antonio , Garlipp Daniel Carlos
Published: August 2016

Objetivo: verificar possíveis associações entre a hipertensão arterial e sobrepeso em crianças e adolescentes. Método: estudo caracterizado como descritivo e associativo com análise de corte transversal. Foram avaliados um total de 321 crianças e adolescentes, sendo 172 do sexo masculino e 149 do sexo feminino, com idades entre 9 e 15 anos. Foram avaliadas a estatura e a massa corporal a fim de se calcular o índice de massa corporal, além da pressão arterial. Para a análise dos dados foram utilizados valores absolutos e em percentual. Nas análises inferenciais foi utilizado o teste do Qui-quadrado. Todas as análises foram realizadas no programa estatístico SPSS, versão 20.0, sendo que o nível de significância estipulado foi de 5%. Resultados: quanto à pressão arterial, 14% dos meninos e 10% das meninas apresentaram hipertensão. Quanto ao IMC, 23,3% dos meninos e 17,4% das meninas foram classificados como estando na zona de risco à saúde. Quando relacionadas à classificação da pressão arterial com a classificação do IMC, foi identificada associação estatisticamente significativa entre hipertensão e presença na zona de risco à saúde em IMC, bem como pressão arterial considerada normal e presença na zona saudável de IMC (p=0,003; Residual Padronizado Ajustado = 3,0). Considerações finais: o sobrepeso e a propensão ao desenvolvimento de HAS (Hipertensão arterial sistêmica) estão significantemente relacionados.
Estereótipos e amorosidade na aventura de Tainá: abordagem ecossistêmica comunicacional e a representação do indígena amazônico
Authors: Baptista Maria Luiza Cardinale , Rodrigues Adriano , Lopes Rafael
Published: August 2016

Este artigo discute o contraponto entre estereótipos e amorosidade, em relação aos índígenas amazônicos, a partir da análise do filme Tainá, uma aventura na Amazônia (2001). Apresenta a realidade dessa comunidade, considerando a complexidade, exuberância e diversidade social, desconstruindo concepções etnocêntricas. Resulta de abordagem transdisciplinar, considerando os pressupostos dos Ecossistemas Comunicacionais, com base em levantamento bibliográfico, observação e análise do filme.
Os corpos biográficos de Fernando Henrique Cardoso: uma abordagem biografemática do jornalismo
Authors: Silva Alexandre Rocha da , Abreu Luis Felipe Silveira de , Araujo André Correa da Silva de
Published: August 2016

Este artigo busca discutir o problema da representação da vida no jornalismo por meio dos conceitos de fait divers e biograema de Roland Barthes. O trajeto teórico é ilustrado por uma análise do perfil “O andarilho”, sobre Fernando Henrique Cardoso. Evidencia-se aí um regime de escrita capaz de apreender não o sujeito, mas sim suas diversas singularidades, representadas por regimes signícos de diferentes níveis de representação.
A grande imprensa e a produção de webdocs: a tradição documentária e as possibilidades de ruptura no ambiente online
Authors: Rezende Renata , Tavares Denise
Published: August 2016

Esse artigo é parte de uma pesquisa sobre os formatos e gêneros acionados pela grande imprensa decorrentes de seu esforço de penetrar na ambiência da Internet de forma mais efetiva. Aqui destacamos, especialmente, o webdocumentário. A metodologia incluiu levantamento realizado em duas etapas em jornais brasileiros, com o objetivo de quanti-ficar a produção que, posteriormente, é analisada em cotejo à tradição documentária e, também, considerando a possibilidade de uma nova modalidade enunciativa no jornalismo que, como intenciona-se demonstrar, ainda se revela rarefeita.
“E para verdade passo este de minha letra e sinal" – uma breve análise sobre cultura escrita e os recibos assinados por Antônio Francisco Lisboa (1772-1802)
Authors: Almada Márcia
Published: August 2016

Neste artigo será estudado um conjunto de 32 recibos assinados pelo escultor/entalhador Antônio Francisco Lisboa, o Aleijadinho, sob a perspectiva da História da Cultura Escrita, integrando-os à dimensão de registros materiais das práticas da escrita na Capitania de Minas Gerais em fins do século XVIII. A partir de análises formais e materiais, estes documentos são percebidos como sinais materializados da trajetória de vida do artista e relacionados criticamente ao que se conhece atualmente sobre sua biografia, resultando em uma pequena colaboração para o longo trabalho de identificação dos conhecimentos adquiridos e aplicados por este sujeito e da forma como participou da(s) cultura(s) de sua época.
Papeis em travessia: o bibliotecário Luís Joaquim dos Santos Marrocos e os Manuscritos da Coroa – século XIX
Authors: Conceição Adriana Angelita da , Meirelles Juliana Gesuelli
Published: August 2016

Com a chegada da Família Real portuguesa ao Rio de Janeiro em 1808, o centro de poder imperial transferia-se para a América. Acompanhada de pessoas importantes da nobreza, a Coroa também transladou consigo apetrechos e muitos simbolismos – refletidos, especialmente, na Casa Real – o que tentaria garantir uma adequada permanência da realeza em terras americanas. Dentre os súditos ilustrados da monarquia, destacamos o bibliotecário Luís Joaquim dos Santos Marrocos, personagem central da discussão deste artigo, cujo objetivo primeiro está em problematizar a natureza das relações interatlânticas entre os papeis impressos e manuscritos da Coroa na primeira metade do século XIX. Ao situarmos tais balizas, o texto tem como foco três principais temáticas a serem examinadas: a) a vida do bibliotecário Luís Joaquim dos Santos Marrocos entre bibliotecas e a prática de escrita de cartas; b) sua relação com os manuscritos da Coroa; e c) a sistematização e catalogação que preparou sobre a documentação manuscrita da coroa portuguesa.
A retórica da história no século XVII
Authors: Cerqueira André Sekkel
Published: August 2016

No presente artigo proponho analisar as práticas de escrita da história no século XVII português. Elegi duas obras, das mais significativas impressas entre 1640 e 1680 em Portugal: Ásia portuguesa, de Manuel de Faria e Sousa, obra mandada imprimir pelo filho do autor, Pedro de Faria e Sousa, em 1666; e História de Portugal Restaurado, de D. Luis de Menezes, terceiro conde da Ericeira, impressa em 1679. A análise das obras ficou restrita aos preambulares, pois é nesta parte em que os autores ou editores escrevem sobre o teor da obra e como ela se enquadra no gênero ao qual pertence – no caso, o histórico. Por se tratar do estudo das práticas de escrita de um gênero, analisei os textos a partir de uma perspectiva retórica, uma vez que eram as artes retóricas que regravam a escrita no período estudado. Assim, identifiquei três autoridades do gênero histórico às quais os autores costumavam recorrer para autorizar o seu discurso: Cícero (do século I a. C.), Luciano de Samósata (século II d. C.) e Agostino Mascardi (século XVII).
El estrés por boro afecta la fotosíntesis y la síntesis de compuestos antioxidantes en plantas. Una revision
Authors: Moreno Darwin L. , Quiroga Ivonne A. , Balaguera-López Helber Enrique , Magnitskiy Stanislav
Published: August 2016

El estrés causado por deficiencia o toxicidad de boro es común en plantas cultivadas. En la actualidad, el papel del boro en la fotosíntesis y sus efectos en este proceso es desconocido. La fotosíntesis puede presentar limitación estomática, debido a la disminución en el intercambio gaseoso; y limitación no estomática, que se caracteriza por disminuciones en la actividad de enzimas relacionadas con el ciclo de Calvin y alteraciones en parámetros de la fluorescencia de la clorofila a, debido al desacople generado entre las fases foto y síntesis de la fotosíntesis, propiciando un aumento en los contenidos de especies reactivas de oxígeno que afectan negativamente algunas moléculas, estructuras celulares y la eficiencia fotosintética. Sin embargo las plantas tienen mecanismos de tolerancia ante esta condición de estrés mediante respuestas antioxidantes enzimáticas (polifenol oxidasa, ascorbato oxidasa, monodeshidroascorbato reductasa, deshidroascorbato reductasa y catalasa) y no enzimáticas (ácido ascórbico, glutation), las cuales varían en su expresión de acuerdo a la especie y al estado fenológico de la misma.
Diagnosis, prevention and organ-preserving method of delivery in pregnant women with placenta accreta
Authors: Khasanov A A
Published: August 2016

The article considers one of the causes of maternal mortality - uterine postpartum bleeding developing as a result of the placental growth into the uterus and surrounding organs. It is highlighted that the processes of trophoblast invasion during pregnancy and tumor progression have much in common. The article describes a significant role of Kiss1-gene and its receptor GPR54 in the placenta accreta development. The causes of placental abnormalities and conventional methods of treatment and surgical management in placenta accreta (controlled uterine balloon tamponade, uterine vessels ligation, uterine compression sutures, uterine artery embolization, internal iliac arteries ligation, temporary clamping or major uterine vessels ligation, hysterectomy, «Triple-P» method) are analyzed, the possible complications of these methods of treatment are listed. The developed at the Department of Obstetrics and Gynecology №1 of Kazan State Medical University examination algorithm when planning pregnancy, gestation management and organ-preserving method of delivery in pregnant women with abnormal placental attachment is presented. Used by authors methods of uterine scar examination after organ-preserving surgery or caesarean section in women in the non-pregnant state (hysterography, hysteroscopy, ultrasound scan, double-contrast study) and sonographic signs of scar failure (myometrial thinning in the scar area, irregular contour of the scar, discontinuous contours of the scar, significant number of hyperechoic inclusions, presence of non-vascular liquid formations in the scar area, triangle in the scar area) are listed. Interesting illustrative material is also presented.
Effectiveness of structured educational programs in increasing adherence to CPAP therapy in patients with obstructive sleep apnea/hypopnea syndrome
Authors: Myrzaakhmatova A K , Sooronbaev T M
Published: August 2016

Aim. To study the effectiveness of a structured educational program in improving adherence to therapy with the creation of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea/hypopnea syndrome.Methods. The study included 40 patients with moderate to severe obstructive sleep apnea/hypopnea syndrome, who received CPAP therapy. Patients were divided into two groups: the first group (main) - 20 patients who had undergone training according to a specially designed structured educational program, the second group (control) - 20 patients who had not received training. CPAP therapy was considered as effective in case of reducing the apnea-hypopnea index to less than 5 per hour of sleep, with an average duration of the machine use for the night was to be more than 5 hours.Results. Using a structured educational program in patients of the main (first) group showed a good adherence of patients and the effectiveness of CPAP therapy. Positive dynamics of clinical symptoms, in particular a decrease in daytime sleepiness, assessed according to Epworth sleepiness scale (17.1±4.2 vs. 3.9±1.6; p=0,0000), was registered, the number of pauses in breathing during the night significantly reduced (44.37±14.6 vs. 2.86±3.5 per hour; p=0,0000), accompanied by improvement of night saturation parameters: SpO2min (58.4±9.0 vs. 78.0±9.3; p=0,0000), SpO2mean (87.2±6.8 vs. 93.1±3.5; p=0,0018). Against this background, after 3 months of therapy a decrease in body mass index and blood pressure was registered.Conclusion. The implementation of a structured educational program showed increase in adherence and the effectiveness of therapy with the creation of continuous positive airway pressure (CPAP therapy) in treating obstructive sleep apnea/hypopnea syndrome.
Using bioresonance therapy in treatment of patients with hypothyroidism
Authors: Kiryanova V V , Vorokhobina N V , Makhramov Z H
Published: August 2016

Aim. To evaluate the effectiveness of using bioresonance therapy in the treatment of patients with hypothyroidism.Methods. Three matched groups of patients with acquired hypothyroidism consisting of 50 people aged 20 to 60 years (mean age 45.6 years) were included in a study. All patients were treated by the same conventional scheme of treatment of hypothyroidism: thyroid hormone replacement drugs. The main group, in addition to replacement therapy received bioresonance therapy. The second group (control) received only pharmacotherapy, the third group (placebo) received pharmacotherapy and simulation of bioresonance therapy procedures. Patients of the main group received 12 daily bioresonance therapy procedures using «Det Professional» device, consisting of two stages: the basic treatment stage and targeted therapy stage. 5 procedures of basic treatment and 7 procedures of targeted therapy were performed.Results. After bioresonance therapy, free thyroxine fraction value in the main group significantly increased in comparison with the control group and the placebo group. Values of thyroid-stimulating hormone after the conducted therapy in the main group significantly decreased compared with the control group and the placebo group. The lipidogram results indicate that the content of high-density lipoproteins in the study group significantly increased compared with the control group and the placebo group. The concentrations of low-density lipoproteins, cholesterol and triglycerides in the main group became significantly lower than in the control group and the placebo group.Conclusion. The obtained results give the evidence of the effectiveness of using bioresonance therapy in combined treatment of patients with hypothyroidism and in achieving stable remission of hypothyroidism.
Antioxidants capabilities in correction of gentamicin-induced nephrotoxicity in experimental infection
Authors: Miroshnichenko A G , Brukhanov V M , Gossen I Ye , Perfilyev V Yu
Published: August 2016

Aim. To assess the antioxidants effectiveness (ascorbic acid, methylethylpiridinol, N-acetylcysteine) in reducing the gentamicin-induced nephrotoxicity in experimental infection caused by Escherichia coli or Klebsiella pneumoniae.Methods. The experiment was divided into two parts. In the first part, the effect of antioxidants on the sensitivity of bacteria to gentamicin in vitro according to changing the optical density of the bacterial suspension, in the second part - nephroprotective activity of antioxidants and their effects on antibiotic activity in experimental bacterial peritonitis were evaluated.Results. All antioxidants significantly reduce the sensitivity of E. coli to gentamicin in vitro, and the level of effect is directly proportional to the antioxidant concentration. Methylethylpiridinol has the most pronounced antagonistic action against gentamicin. It is found that methylethylpiridinol at a concentration of 4 mmol/l enhances development of Escherichia coli strain by 7 times by the 6th hour of incubation. Ascorbic acid and N-acetylcysteine have a similar probacterial activity profile. In the incubation mixtures containing a strain of Klebsiella pneumoniae, a similar pattern of increase in bacterial biomass optical density was observed with maximum values in the presence of the highest concentrations of antioxidants. In experimental infection, antioxidants reduce the activity of gentamicin against Escherichia coli and Klebsiella pneumoniae, without reducing the antibiotic nephrotoxicity.Conclusion. Ascorbic acid, methylethylpiridinol and N-acetylcysteine reduce the antibacterial activity of gentamicin against Escherichia coli and Klebsiella pneumoniae in vitro and in vivo, in a dose of 80 mg/kg they do not reduce gentamicin nephrotoxicity in bacterial peritonitis in rats; their use in the course of treatment with gentamicin is not only irrational, but also contraindicated.