bluuebunny/crossref_metadata_2025 huggingface dataset:
Advanced Grid Connectivity Using Hybrid Solar, Wind, and Battery Technologies
Authors: Mukundswamy M S  , Abhishek V  , Abhinav Yadav  , Rahil M  , Yogeshwar C  , Dr G V Jayaramaiah
Published: June 2024

Global warming has led to the proliferation of electric vehicles, which seem to be the best option for internal combustion engines. With so many electric cars on the road, it's not practical or economical to charge cars using traditional power lines. Using renewable energy when charging stations control the electric vehicle. The project describes the charging system (SWCM) based on solar energy (250W), 15 modules in series and 2 parallel in series, and wind power (5.78kW) to generate electricity to charge the battery of the EV (electric vehicle). The regenerative charging station consists of wind turbines and PV (solar photovoltaic) modules. Charging mechanisms based on wind energy reduce CO2 and CO2-related emissions by reducing the need for fossil fuels to generate electricity. EV (electric vehicle) charging stations containing solar, wind, grid and BESS (battery energy storage systems) are designed according to the current situation. Additional grid support is also assumed to provide uninterrupted power to the charging stations without placing additional load on the grid. To balance the requirements, the system is connected to the grid via a three-phase bidirectional DC-AC (alternating current) frequency converter. The results show that the regenerative power generator is suitable for charging electric vehicles and creating a Pollution-free environment. The results are demonstrated with a MATLAB simulation run.
Deep Learning in Cricket: A Comprehensive Survey of Shot Detection and Performance Analysis
Authors: Milind Mahajan  , Shreekar Kulkarni  , Mitesh Kulkarni  , Abhishek Sabale  , Aakanksha Thakar
Published: June 2024

Cricket shot detection and performance analysis have become increasingly significant in the realm of sports analytics. This paper presents a comprehensive survey of recent advancements in cricket shot detection and performance analysis using deep learning techniques. Through a systematic review of ten research papers, various methodologies, algorithms, and approaches employed in the field were examined. The surveyed papers showcase the application of deep convolutional neural networks (CNNs), transfer learning, and multimodal feature integration for accurate shot detection and outcome classification. Additionally, the survey highlights common processes such as data preprocessing, model training, and evaluation metrics, while also discussing the integration of features extracted from video, audio, and image modalities. Through a detailed literature review, this paper analyzes the similarities and differences in approaches, methodologies, and results across the surveyed papers. Furthermore, this survey identifies opportunities for future research and development to advance the field of cricket shot detection and performance analysis. Overall, this survey provides valuable insights into the state-of-the-art techniques and challenges in utilizing deep learning for cricket analytics, offering guidance for researchers and practitioners in the domain.
THE LIVING PRINCIPLE IN HUMAN. PART II. HISTORICAL AND PHILOSOPHICAL ANALYSIS OF NON-CLASSICAL AND MODERN PHILOSOPHY
Authors: Solomko Dmitry V. , Lavelin Vadim D.
Published: June 2024

This article is the second part, a continuation of the historical-philosophical analysis presented earlier in the article “The Living Principle in Human. Part I. Historical and philosophical analysis of classical philosophy” and reflects the results of the analysis of the main part of non-classical and modern philosophy. As a result of the conducted research the general definition is formulated and attributive properties of the living principle in human are revealed. It is defined that the living principle in human is a set of system-organized components of human being, each time manifesting itself spontaneously and reproduced in its unique, unique form. The main attributes are: organic integrity, universality, spontaneity, irreducibility, immediacy, openness to the world.
A NEW CLASS OF GIBBS MEASURES FOR THREE-STATE SOS MODEL ON A CAYLEY TREE
Authors: Rahmatullaev M. M. , Abraev B. U.
Published: June 2024

The phase transition phenomenon is one of the central problems of statistical mechanics. It occurs when the model possesses multiple Gibbs measures. In this paper, we consider a three-state SOS (solid-on-solid) model on a Cayley tree. We reduce description of Gibbs measures to solving of a non-linear functional equation, each solution of which corresponds to a Gibbs measure.We give some sufficiency conditions on the existence of multiple Gibbs measures for the model. We give a review of some known (translation-invariant, periodic, non-periodic) Gibbs measures of the model and compare them with our new measures. We show that the Gibbs measures found in the paper differ from the known Gibbs measures, i.e, we show that these measures are new.
MIXED PROBLEM FOR A NONLINEAR IMPULSIVE DIFFERENTIAL EQUATION OF PARABOLIC TYPE
Authors: Yuldashev T. K. , Fayziyev A. K. , Rakhmonov F. D.
Published: June 2024

In this paper, we consider a nonlinear impulsive parabolic type partial differential equation with nonlinear impulsive conditions. Dirichlet type boundary value conditions with respect to spatial variable is used, and eigenvalues and eigenfunctions of the spectral problem are founded. The Fourier method of the separation of variables is applied. A countable system of nonlinear functional equations is obtained with respect to the Fourier coefficients of the unknown function. A theorem on a unique solvability of the countable system of nonlinear functional equations is proved by the method of successive approximations. A criteria of uniqueness and existence of a solution for the nonlinear impulsive mixed problem is obtained. A solution of the mixed problem is derived in the form of the Fourier series. The absolute and uniform convergence of the Fourier series is proved.
NEWTON’S METHOD IN CONSTRUCTING A SINGULAR SET OF A MINIMAX SOLUTION IN A CLASS OF BOUNDARY VALUE PROBLEMS FOR THE HAMILTON - JACOBI EQUATIONS
Authors: Lebebev P.D. , Uspenskii A.A.
Published: June 2024

The non-smooth features of the minimax (generalized) solution of the considered class of Dirichlet problems for equations of Hamiltonian type are due to the existence of pseudo-vertices - singular points of the boundary of the boundary set. The paper develops analytical and numerical methods for constructing pseudo-vertices and their accompanying constructive elements, which include local diffeomorphisms generating pseudo-vertices, as well as markers - numerical characteristics of these points. For markers, an equation with a characteristic structure inherent in equations for fixed points is obtained. An iterative procedure based on Newton’s method for the numerical construction of its solution is proposed. The convergence of the procedure to the pseudovertex marker is proved. An example of the numerical-analytical construction of a minimax solution is given, illustrating the effectiveness of the developed approaches for constructing nonsmooth solutions of boundary value problems.
METRICAL BOCHNER CRITERION AND METRICAL STEPANOV ALMOST PERIODICITY
Authors: Kosti´c M. , Fedorov V. E. , Koyuncuo˘glu H. C.
Published: June 2024

We analyze the metrical Bochner criterion and a new class of multi-dimensional metrically Stepanov almost periodic type functions. We clarify the main structural properties for the introduced classes of functions, including the Bochner criterion, and provide certain applications to Doss-p-almost periodic functions. We also study the extensions of almost periodic sequences and briefly explain how we can apply the established theoretical results to the abstract Volterra integro-differential equations.
Legal Politics of the President's Grant of Lesion Basedon the Perspective of Justice and Humanity in the Indonesian Judicial System
Authors: Zilya Lirungan Cheryll , Supriyadi  , Susianto
Published: June 2024

This research aims to explore and understand the legal politics behind granting a Pardon by the President of Indonesia in the justice system and the factors influencing the decision to grant a Pardon. The research method used is normative legal research, which focuses on positive legal analysis, legal principles, and legal doctrine. The approach usedincludes a statutory approach to analyze related regulations and a conceptual approach. The research results show thatGranting a Pardon by the President is a constitutional right that the President has without interference from other institutions. After the amendment to the 1945 Constitution of the Republic of IndonesiafourthSometimes there are restrictions on the President's powers, which are considered too broad, and to prevent authoritarianism from the President. In line with these changes, especially in granting pardons, the President must pay attention to the considerations of the Supreme Court. This is not an intervention by the President in the Judiciary institution. However, with a checks and balances mechanism, the President has the basis for consideration from the institution concerned even though the decision to grant it is purely based on the President's constitutional rights
A Comprehensive Analysis of Monitoring and Control Mechanisms in Operational Relocation Project at Limkokwing University, Botswana
Authors: Kelepile Lenah Cleo
Published: June 2024

The analysis of project monitoring and control processes holds paramount significance in project management and delivery, attracting considerable attention within academic discourse. The study explores the intricacies of project monitoring and control, particularly in the context of operational relocation at Limkokwing University of Creative Technology Botswana. The study employs a comprehensive survey methodology, encompassing all project team members and university management, stratified by department, and tasked with responding to structured questionnaire items. Analysis of the gathered data unveils proficient performance in project monitoring and control, underscored by systematic reviews of project progress and interface oversight. Based on the insights gleaned from this investigation, the study urgently recommends the establishment of a specialized monitoring and control unit or function within the university’s organizational framework. This is not just a suggestion, but a crucial step to address developmental exigencies or challenges, and to enhance the prospects of successful project outcomes. However, the study also identified certain barriers to success, including inadequate staff coordination, a need for more skilled personnel with requisite experience, and resistance to organizational change. Therefore, further research is necessary to refine and optimize the efficacy of monitoring and control processes, taking into account these key factors.
Stranded at Home: Lived Experiences of Ilonggo Seafarers.
Authors: Jane P. Garcia, Mary
Published: June 2024

This qualitative phenomenological study delves into the distinctive experiences of Ilonggo seafarers who unexpectedly found themselves stranded at home due to the disruptive COVID-19 pandemic. Before the global outbreak, these individuals led transient lives as migrant explorers, traversing the world’s oceans as seafarers. However, their lives took an abrupt turn when they were grounded due to various pandemic-related factors and containment measures. The research commences by providing an insightful exploration of their pre-pandemic lives, vividly portraying the dynamics of the seafaring industry they were an integral part of. It then sharply contrasts these experiences with the arduous challenges they faced while confined to their homes during the pandemic’s onset. Employing in-depth interviews and rigorous thematic analysis, this study unveils the multifaceted struggles, stresses, and emotional challenges that these seafarers grappled with during their unanticipated hiatus. It also sheds light on the diverse coping mechanisms they resorted to, including venturing into business, seeking online employment, embracing newfound recreational activities, strengthening familial bonds, and actively engaging in community outreach initiatives. Grounded in the remarkable resilience and adaptability demonstrated by these seafarers, puts forth practical recommendations such as advocating for the recognition of seafarers as “Key or Essential Workers” and endorsing measures such as accessible online training, and the establishment of the Philippines Port as a Crew Change Hub. These initiatives collectively aim to fortify seafarer well-being and enhance the overall resilience of the maritime industry.
Teachers’ Utilization of Bloom’s Cognitive Taxonomy in Examination in Public Secondary Schools in Nandi County, Kenya
Authors: Yegon Bernard Kipkurui , Maiwa Jeniffer Chepkoech
Published: June 2024

Stakeholders are generally concerned in how public secondary schools perform academically in contrast to private schools. The optimal application of Bloom’s Taxonomy should foster increased performance. Thus, the purpose of the study was to ascertain how students’ academic achievement in public secondary schools in Nandi County, Kenya, related to teachers’ application of Bloom’s Cognitive Taxonomy in teaching and examination. The study’s goal was to find out how instructors used Bloom’s Taxonomy when creating internal exams. A pragmatic paradigm was used in the investigation. The foundation of this study was Bloom’s Cognitive Taxonomy. This study used an explanatory sequential design in conjunction with a mixed method research technique. The research population consisted of 2055 teachers from 137 public secondary schools. The sample size was 360 teachers from 30 county schools. 30 county schools were selected using simple random sampling, from which 12 Form 3 teachers teaching 6 selected subjects were identified. Questionnaires and document analysis were used to collect data from examination. Data was analyzed using frequencies, and means. The results showed that 86 % of the teachers utilized Bloom’s Taxonomy when setting exams. The overall percentages for using Bloom’s Cognitive Taxonomy in examination papers were as follows: remembering 29.4%, understanding 28.5%, applying 14.5%, analyzing 9.9%, evaluating 8.7%, and creating 8.8%. The study therefore concluded that, most teachers used Bloom’s Taxonomy when developing internal tests, and recommended that all teachers should utilize Bloom’s Taxonomy and maximize all the levels of it in exams so as to promote an insightful approach to learning and critical thinking experience that will enhance academic performance for the students.
Dharma and Dynamics; Integrating The Bhagwat Gita’s Eternal Wisdom with Modern Management Principles
Authors: Vatsalya Sharma  , Ms. Aparna Vats
Published: June 2024

The purpose of the study is to explore the fundamental message of The Bhagwat Gita and its influence on management policies. It is the holy scripture of the Hindus is a part of the religious epic Mahabharata. This study discover how there is interconnectedness in the various management teams. The Gita explains the interconnectedness of all existence. This interconnectedness helps us to understand divinity in all beings The Bhagwat Gita offers profound wisdom that can be adapted to modern management principles. The study is descriptive in nature hence it uses secondary sources of data. The secondary data is collected from newspapers, articles, research journals government and non-government reports. It is observed that The GITA provides most treasured timeless principles that can enrich modern management practices. By integrating the teachings of the Bhagwat Gita, managers and team leaders can create purpose driven organization that will benefit the individuals and society at large. This study tries to fill the gap in the literature review by studying the fundamental message of The Bhagwat Gita and its influence on management policies and explore how the managers can foster innovation and excellence by following the guidelines of The Bhagwat Gita. Very few studies have been conducted that discover interconnection between The Bhagwat Gita and various management teams.
Exploring the Entrepreneurial Micro-Ecosystem: Agribusiness Among Youth in Rural South Africa
Authors: Kele Tumo Paulis , Dzansi Dennis Y.
Published: June 2024

In recent times, entrepreneurial ecosystems have increasingly being researched and seen as a vehicle for empowerment and poverty alle-viation by policy-makers, particularly in developing economies. Scholars have primarily studied this concept in developed markets, with a focus on urban regions in those markets. However, in the South African context, there is an increasing realization that entrepreneurship among youth in small towns and villages is key in unlocking economic development and self-sustainability in those areas. Thus, research in these regions is necessary for deeper understanding and scholarly engagement into the entrepreneurial ecosystems emerging among youths. In addressing insufficient attention to small town and village entrepreneurship ecosystems, a conceptual comparative-case study of three agribusinesses in rural Eastern Cape province of South Africa was conducted. Thus, the research examines how and to what extent entrepreneurial activities among youth in rural areas manifested in promising agribusinesses within a short space of time, after being affected by Covid-19 lockdowns. The findings depicted that (a) agribusiness is key in rural areas and among youth, (b) rural communities engage in community-based agricultural projects to encourage self-sustainability and entrepreneurship, and (c) there is a need for a more focused support by policy-makers in these areas for them to flourish and open more markets.
Understanding the Role of Human Resource Management, Leadership, and Organizational Culture in Improving Employee Performance: Case Study in the Partnership Division
Authors: Yuwono Matias Andika , Rachmawati Dyna
Published: June 2024

This research examines how human resource management practices, leadership style, company culture, commitment levels, and motivation influence how healthy employees perform in partnership divisions of plantation companies. It uses research methods to explore how these factors work together to create an environment encouraging employees to give their best. The research reveals that work motivation is a critical driver, and it can be enhanced by HR practices such as financial incentives, training opportunities, and giving employees more responsibility. Organizational commitment fostered through regular training and providing adequate resources further fuels motivation. There may be variations in how managers and staff interpret the company culture. However, values like integrity, collaboration, and adaptability are still essential for creating an environment that supports high performance. Effective leadership, focusing on motivating employees, providing guidance, and fostering a positive work environment, also significantly impacts performance. This research, informed by data collected directly from employees in partnership divisions, offers valuable insights. Organizations can optimize employee performance by understanding these factors through targeted human resource strategies and leadership practices tailored explicitly to partnership divisions.
Peran Masyarakat Adat dalam Pengembangan Pendidikan Berbasis Lingkungan Sosial
Authors: Qomarrullah Rifiy
Published: June 2024

Penelitian ini mengkaji peran masyarakat adat dalam pengembangan pendidikan berbasis lingkungan sosial di Kabupaten Jayapura. Urgensi penelitian ini terletak pada pentingnya melestarikan pengetahuan lokal dan budaya masyarakat adat di tengah arus globalisasi yang kuat. Tujuan dari penelitian ini adalah untuk memahami bagaimana pengetahuan lokal dan nilai-nilai budaya masyarakat adat dapat diintegrasikan ke dalam kurikulum pendidikan formal. Metode penelitian yang digunakan adalah pendekatan kualitatif dengan wawancara mendalam, observasi partisipatif, dan analisis dokumen. Hasil penelitian menunjukkan bahwa masyarakat adat memainkan peran sentral dalam mendukung pendidikan yang relevan secara lokal. Mereka terlibat aktif dalam pengembangan kurikulum, menyediakan materi pengajaran berbasis budaya, dan berpartisipasi dalam kegiatan sekolah. Selain itu, keterlibatan masyarakat adat dalam pendidikan formal membantu mempertahankan identitas budaya dan memperkaya pengalaman belajar siswa. Penelitian ini menyimpulkan bahwa integrasi pengetahuan lokal dan nilai-nilai budaya dalam pendidikan formal dapat meningkatkan kualitas pendidikan serta mempromosikan keberlanjutan budaya dan lingkungan. Ditemukan pula bahwa kolaborasi antara pemerintah, masyarakat adat, dan lembaga pendidikan sangat penting dalam upaya ini. Penelitian ini memberikan rekomendasi praktis untuk implementasi pendidikan berbasis lingkungan sosial yang dapat diterapkan di Kabupaten Jayapura dan wilayah lainnya dengan konteks serupa. Rekomendasi tersebut mencakup pengembangan kebijakan pendidikan yang mendukung kolaborasi multi-pihak, pelatihan guru dalam materi budaya lokal, dan peningkatan kesadaran akan pentingnya melestarikan pengetahuan adat melalui pendidikan.
AUTISMO E SUAS POSSÍVEIS CAUSAS
Authors: Faria Maria Elisa Vaz de , Borba Marcia Guaraciara de Souza
Published: June 2024

Este artigo buscou discutir as possíveis causas do autismo, um transtorno caracterizado por inúmeros prejuízos comportamentais e cognitivos, que compromete habilidades físicas, psicológicas, emocionais e sociais e cuja etiologia ainda não está definida. Tendo em vista o crescente interesse público pela questão do autismo, o aumento exponencial de diagnósticos do transtorno e a busca por mais informações a respeito do tema, tornou-se imprescindível o estudo mais profundo de suas possíveis causas. O presente trabalho tem como objetivo ajudar a sanar esta lacuna para contribuir com o diagnóstico e nortear possíveis ações a serem desencadeadas, tanto para a inclusão quanto para a melhoria da qualidade de vida do acometido pelo Transtorno do Espectro Autista. A pesquisa foi realizada com as palavras-chave Autismo e Causas, associadas, ou Autismo separadamente, sendo considerados válidos os documentos que apresentassem esses termos no título e/ou resumo.As fontes de busca foram restritas aos materiais em meio digital, disponibilizados no site da Universidade de São Paulo (USP); no site da Academia.edu, bem como ao site SCIELO. Os períodos de coleta de materiais foi entre 2015 e 2024, sendo estabelecida esta limitação para os materiais revisados. Realizou-se uma triagem, selecionando apenas os materiais relacionados diretamente ao conhecimento do transtorno e suas respectivas causas e que atendesse ao objetivo estabelecido.
ANÁLISE EPIDEMIOLÓGICA DOS CASOS DE HIV NO BRASIL EM HOMENS DE 50 a 79 ANOS, ANTES E APÓS A COMERCIALIZAÇÃO DO CITRATO DE SILDENAFILA NO PERÍODO DE 1986 A 2010
Authors: Girotto Suyanne Paula Schwade , Possobon Adriano Luiz , Flandoli Amanda Letícia Schell , Vicente Andressa Gonçalves , Hortolam Isabela Monteiro , Santos Thiago Assis
Published: June 2024

O Vírus da Imunodeficiência Humana (HIV) permanece sendo um problema de saúde pública no Brasil e no mundo, com milhões de mortes até a atualidade. O aumento da infecção pelo HIV no público acima de 50 anos tem crescido nas últimas décadas, principalmente pela valorização do público de meia idade e idosos, pois passaram a ser vistos além de apenas pessoas capazes de realizar tarefas de idade avançada, mas sim, ser visto como pessoas desejáveis e sexualmente ativas. Com a comercialização do citrato de sildenafila no Brasil, fármaco mais conhecido como viagra, esse público alvo ficou mais exposto a práticas sexuais de risco sem proteção e ao aumento do número de parceiros, devido ao bom desempenho que a medicação oferece. Com isso, questiona-se se a chegada do Viagra aumentou o número de casos de HIV nessa população.
O IMPACTO PSICOLÓGICO DO TRANSTORNO ALIMENTAR E PROCESSOS BARIÁTRICOS: UMA ABORDAGEM INTEGRATIVA PARA A SAÚDE MENTAL E O BEM-ESTAR DO INDIVÍDUO
Authors: Monteiro Julia da Rocha Areal , Ramos Júlia de Moura , Santos Mariana Fernandes Ramos dos
Published: June 2024

O artigo destaca a importância da psicoterapia como um espaço seguro para a expressão e compartilhamento de experiências emocionais, promovendo a construção coletiva de significados que podem ser explorados para encontrar soluções de os desafios enfrentados no dia a dia. Espera-se que este trabalho contribua para a compreensão dos Transtornos Alimentares e a Cirurgia bariátrica pré e pós, identificando os principais sintomas, o impacto do diagnóstico na vida do paciente e a relevância do psicólogo no processo de tratamento. O papel do psicólogo no atendimento a pacientes diagnosticados com distúrbios alimentares foi discutido neste artigo, assim como o papel da família e fatores que influenciam o surgimento/desenvolvimento de Transtornos Alimentares. O estudo adotou uma abordagem integrativa, revisando a literatura disponível em livros e periódicos especializados sobre transtornos alimentares e a cirurgia bariátrica. Como tal, trata-se essencialmente de uma revisão bibliográfica.
Fonction et évolution des séquences répétées dans les génomes
Authors: Richard Guy-Franck
Published: June 2024

Le génome des êtres vivants est composé de séquences d’ADN d’origines diverses, dont le rôle est parfois difficile à appréhender. Au-delà des gènes, dont le produit a une fonction biologique pouvant être inférée par l’expérimentation, certaines séquences, présentes en un grand nombre de copies, échappent encore aux approches les plus fines visant à élucider leur rôle précis.L’existence de ce que les généticiens du XXe siècle avaient déjà perçu, et décrit à tort comme de « l’ADN poubelle », fut confirmé par le séquençage des premiers génomes complexes, dont celui d’Homo sapiens. Une large partie de ce qui définit le vivant n’est pas unique mais répété, parfois un très grand nombre de fois, augmentant la complexité par duplication et multiplication successives.Comprendre et définir les nombreuses fonctions de cette myriade de séquences répétées, ainsi que leur évolution sous l’effet de la sélection naturelle et de la dérive génétique, est devenue l’un des enjeux majeurs de la génomique du XXIe siècle.
La méthode Rock-Eval®
Authors: Baudin François
Published: June 2024

La méthode Rock-Eval®, inventée en France dans les années 1970, est devenue un outil largement utilisé dans le monde entier par l’industrie pétrolière pour caractériser les roches mères, les roches réservoirs et évaluer leur potentiel en hydrocarbures. Au fil du temps, son utilisation s’est étendue à d’autres domaines tels que, entre autres, la pédologie, la paléocéanographie, la paléoclimatologie, les sciences de l’environnement ou la chimie des matériaux (carbonates, microplastiques).Cet ouvrage explore la méthode Rock-Eval®, ses divers domaines d’application et envisage ses évolutions potentielles. Il bénéficie de l’expertise d’un large panel d’auteurs issus tant du milieu académique que de l’industrie, tous ayant contribué au développement de cet outil et de sa méthodologie. Cet instrument, fusionnant les caractéristiques d’un analyseur chromatographique, thermique et élémentaire, évolue désormais vers une plateforme analytique ouvrant la voie à de nouvelles applications à explorer à l’avenir.
TERRA, les ARN télomériques non codants
Authors: DECOTTIGNIES Anabelle
Published: June 2024

Les ARN télomériques non-codants, TERRA, ont été détectés dans de nombreuses espèces eucaryotes. Leurs fonctions ne sont pas complètement élucidées mais ils semblent jouer d'importants rôles de protection des télomères. Même si l'origine chromosomique des TERRA diffère entre la souris et l'homme, ils pourraient remplir des fonctions semblables en étant recrutés aux télomères en trans.
Physiopathologie des télomères
Authors: KANNENGIESSER Caroline , REVY Patrick
Published: June 2024

Les téloméropathies regroupent des pathologies constitutionnelles causées par des mutations dans des gènes de la maintenance ou de la protection des télomères. L’expression clinique et la sévérité sont variables. Les patients adultes présentent des fibroses pulmonaires et/ou des atteintes hépatiques. Chez les enfants avec insuffisance médullaire, une diminution anormale de la taille des télomères peut être mesurée dans le sang.
Agents ciblant les télomères
Authors: BOMBARD Sophie , MAILLIET Patrick , TEULADE-FICHOU Marie-Paule
Published: June 2024

Les télomères, structures nucléoprotéiques situées à l’extrémité des chromosomes sont impliqués dans la maintenance du génome. Ce chapitre décrit les différentes classes d’agents chimiques ciblant les télomères en utilisant soit leurs structures secondaires d’ADN (G-quadruplexes) soit les protéines associées (Shelterine, télomérase). Les effets biologiques résultants de ce ciblage spécifique s’inscrivent dans une approche de découverte de nouveaux agents anticancéreux.
Une brève histoire de la télomérase : des femmes d’exception aux commandes
Authors: GÉLI Vincent
Published: June 2024

Ce chapitre retrace la découverte de structures d’ADN répétées, riches en G, situées à l’extrémité des chromosomes qui ont été baptisées « Télomères » et de l’enzyme qui synthétise ces motifs, appelée télomérase. Ces découvertes, ayant des implications essentielles sur le vieillissement et le cancer, vaudront à Elizabeth Blackburn, Carol Greider et Jack Szostak le prix Nobel de médecine.
La télomérase : structure et mécanisme
Authors: SAINTOMÉ Carole
Published: June 2024

La télomérase est un complexe ribonucléoprotéique qui permet de maintenir une division illimitée des cellules en allongeant les télomères. Ce chapitre présente la télomérase d'un point de vue de sa structure, de sa biogenèse et de son mécanisme d'action pour allonger les télomères, ainsi que les différentes voies qui permettent de réguler son activité.
Les duplications complètes du génome, une redondance à l’échelle du génome entier
Authors: PAREY Elise , BERTHELOT Camille
Published: June 2024

Les duplications complètes du génome sont un phénomène évolutif au cours duquel le génome double en taille et en contenu. Cette source de redondance majeure a donné naissance à de nombreuses familles de gènes dans le génome humain, mais également à l’organisation génétique complexe de nombreuses espèces. Ce chapitre décrit leurs mécanismes d’apparition ainsi que leurs conséquences fonctionnelles et évolutives.
G-quadruplex : structure, détection et fonctions
Authors: PUIG LOMBARDI Emilia
Published: June 2024

Les G-quadruplex (G4), structures secondaires pouvant être adoptées par les acides nucléiques, jouent des rôles biologiques dans de nombreux processus cellulaires : maintenance des télomères, réplication cellulaire, réarrangements génomiques, réponse aux dommages de l’ADN, régulation transcriptionnelle. Par ailleurs, dans le génome humain, il existe une forte présence de séquences potentiellement capables de former des G4. Ces observations mènent à la question de comment ces séquences se forment in vivo, sont maintenues dans les génomes et comment elles évoluent.
Mise en oeuvre de l’HACCP : hygiène des surfaces
Authors: OULAHAL Nadia , PERRET Sylvie , BORNUA Denis
Published: June 2024

Il s’agit de la mise en place de l’approche HACCP pour assurer l’hygiène de toutes les surfaces sujettes à ces contaminations microbiennes indésirables. Cette démarche est entièrement détaillée conformément aux normes et réglementation.
Rôle des surfaces et phénomène microbien
Authors: SLATE Anthony J. , WILSON-NIEUWENHUIS Joels S.T. , SPALL Joshua H. , WHITEHEAD Kathryn A.
Published: June 2024

Les interactions entre les bactéries et les matériaux sont particulièrement détaillées. Elles sont très largement influencées par la physicochimie, la chimie et la topographie des surfaces. A partir de la connaissance des phénomènes impliqués, des solutions pour remédier aux conséquences négatives pour l’hygiène des surfaces sont proposées.
Conception hygiénique : usine
Authors: HOLAH John
Published: June 2024

La conception hygiénique des usines alimentaires permet d’assurer à l’usine une protection contre les risques externes et internes y compris la protection de la marque ; une gestion optimale des flux internes de personnes, des ingrédients, des produits, des emballages, d'air et de déchets pour prévenir la contamination croisée ; et le maintien de conditions hygiéniques grâce à la rigidité structurelle et à la durabilité des matériaux.
Les opérations de nettoyage : état de la pratique
Authors: TIMMERMAN Hein
Published: June 2024

L’état de la pratique des opérations d’hygiène dans les usines alimentaires est présenté. La présentation des technologies disponibles et leurs intérêts inclue aussi bien les technologies dites intelligentes que d’autres technologies émergentes utilisées à travers l’ensemble de la chaine d’approvisionnement alimentaire. Cela permet une meilleure appréhension de la valeur ajoutée que ces technologies peuvent apporter au secteur. Par ailleurs, les évolutions récentes de l'adoption du paradigme de l’Internet des Objets (IdO) sont également présentées.
Caractérisation et évaluation de la stabilité de la matière organique du sol
Authors: BARRÉ Pierre , CÉCILLON Lauric , KANARI Eva
Published: June 2024

Ce chapitre propose une synthèse des travaux utilisant l’analyse thermique Rock-Eval® pour étudier la matière organique des sols. Il mentionnera certaines zones d’ombre ou précautions à prendre et discutera des larges perspectives ouvertes par l’utilisation du Rock-Eval® pour l’étude de la dynamique du carbone organique dans les sols.
Étude des évènements naturels et anthropiques
Authors: COPARD Yoann , BAUDIN François
Published: June 2024

Ce chapitre présente des exemples de l’utilisation de la méthode Rock-Eval® pour identifier des événements géologiques (hydrothermalisme, métamorphisme, radiolyse, etc.) ou anthropiques (incendie, oxydation artificielle) impactant la signature habituelle des thermogrammes.
Quelle suite pour le Rock-Eval® ?
Authors: BAUDIN François , BOUTON Nicolas
Published: June 2024

Ce court chapitre évoque de possibles pistes d’évolution de l’appareil Rock-Eval® avec la détection spécifique de nouveaux effluents générés lors de la pyrolyse ou de l’oxydation. Il envisage aussi de futurs domaines d’application pour l’appareil et la méthode.
Caractérisation des roches mères pétrolières
Authors: ROMERO-SARMIENTO Maria-Fernanda
Published: June 2024

Ce chapitre résume les différentes applications du Rock-Eval® pour la caractérisation des roches mères pétrolières, des kérogènes et des huiles dans les réservoirs conventionnels. Il détaille également comment déterminer les volumes d’hydrocarbures lorsqu’ils restent piégés dans la roche mère.
Détermination des paramètres de craquage thermique de la matière organique fossile
Authors: BEHAR Françoise
Published: June 2024

Les paramètres cinétiques du craquage thermique des kérogènes peuvent être déterminés en réalisant des pyrolyses Rock-Eval®. Ce chapitre rappelle les équations de la cinétique de formation du pétrole et montre comment les données de l’analyse Rock-Eval permettent de déterminer les paramètres que sont l’énergie d’activation et le facteur de fréquence.
Les réseaux de villes
Authors: BRIOT Ninon
Published: June 2024

Ce chapitre est consacré aux effets des coopérations internationales entre villes sur les découpages en Europe. Ces liens sont de plus en plus investis par les villes et maillent le territoire communautaire. L’Union européenne incite les villes à coopérer dans une perspective d’européanisation et de renforcement du sentiment d’appartenance européenne.
Trois figures de découpage par l’UE : NUTS, macrorégions et espaces transfrontaliers
Authors: BOULINEAU Emmanuelle
Published: June 2024

Ce chapitre présente trois découpages par l’UE : la NUTS (Nomenclature des unités territoriales et statistiques), les macrorégions et les espaces transfrontaliers traduisent respectivement trois figures de découpage, à savoir un maillage, un zonage et une typologie. Il interroge leur sens, leur finalité et leurs limites dans une UE travaillée par la territorialité étatique et le besoin d’appropriation démocratique.
Les découpages des campagnes européennes
Authors: DEPRAZ Samuel
Published: June 2024

Les mutations des campagnes européennes ont motivé depuis la fin du XXe s. des politiques d’aménagement du territoire ciblées en faveur d’une nouvelle catégorie territoriale, les espaces ruraux. Cependant les découpages urbain/rural sont faussement simples, traduisant surtout les différences culturelles d’appréhension des problèmes socio-économiques des campagnes selon chaque contexte national. Tout en rappelant le sens des concepts et la signification du binôme urbain/rural, ce chapitre fait état de l’hétérogénéité des critères existants et de leur caractère politique. Il montre également l’effort de convergence en cours pour tenter une harmonisation opérationnelle de la définition du rural à l’échelle européenne.
La educación basada en la comunidad desde las percepciones de estudiantes: un estudio cualitativo
Authors: Hurtado Maria del Carmen , Monteverde Ana Clara
Published: June 2024

Introducción. La Universidad del Norte Santo Tomás de Aquino (UNSTA) presenta como nueva oferta de grado la carrera de medicina, que enfatiza un enfoque orientado a la familia y la comunidad. El programa de estudio incorpora la educación basada en la comunidad (EBC), desde el primer al último ciclo de la carrera.
Objetivos. Indagar acerca de las percepciones que los estudiantes que cursaron el primer año de medicina en la UNSTA tienen acerca de sus  experiencias en EBC y caracterizar la valoración que le otorgan al contacto precoz con la comunidad. 
Material y métodos. Estudio cualitativo, paradigma hermenéutico. Modo de generación conceptual, método de análisis de la teoría fundamentada a partir de entrevistas en profundidad.
Resultados. Según la percepción de estudiantes, la EBC permite abrir la cabeza (descubrir otras realidades, chocarse con otros contextos, construir otra idea de médico); significa nutrirse de la práctica temprana (tener una marca para toda la carrera, salirse del libro, aprender de la salud pública local, conocer a un esencial invisible, valorar los diagnósticos de situación locales, sentirse parte y ponerse el delantal); posibilita aprender más allá de la medicina (generar un estudio más reflexivo, vivir el trabajo en equipo, mejorar las habilidades comunicacionales, entender a la persona como un todo e iniciar un compromiso social).
Conclusiones. Los hallazgos subrayan los numerosos beneficios de un plan de estudio que integre la EBC desde el principio. No solo fomenta el aprendizaje reflexivo, sino que también facilita un proceso clínico centrado en la persona y su contexto, iniciando así un compromiso social.
HUBUNGAN KECERDASAN EMOSIONAL DENGAN KEMAMPUAN PERENCANAAN KARIR SISWA
Authors: Reja Yayang
Published: June 2024

SMK adalah satuan pendidikan yang mengedepankan pengembangan keterampilan yang dibutuhkan siswa di dunia kerja. Perencanaan karir di SMK sudah dimulai sejak awal masuk sekolah, diantaranya ketika siswa menentukan akan melanjutkan pendidikan, menentukan jurusan yang diambil, dan menentukan ekstrakulikuler serta kegiatan di luar sekolah yang diambil bagi pengembangan keterampilan guna pendukung tujuan karirnya, tentu pilihan-pilihan tersebut perlu dilakukan secara mandiri oleh siswa. Hal tersebut merupakan bagian dari kecerdasan emosional. Tujuan penelitian ini yaitu untuk membuktikan hubungan kecerdasan emosional terhadap kemampuan perencanaan karir siswa.Penelitian ini menggunakan metode kuantitatif dengan jenis korelasional. Populasi dalam penelitian ini berjumlah 100 siswa, dengan teknik pengambilan sampel meted teknik random sampling. Maka diperoleh sampelnya berjumlah 79 siswa kelas XI TKJ SMK PGRI Palimanan tahun ajaran 2019/2020. Alat pengumpulan data yang digunakan yaitu skala kecerdasan emosional dan skala Kemampuan perencanaan karir. Reliabilitas skala diuji dengan menggunakan Alpha Cronbach dengan koefisien kecerdasan emosional sebesar 0,860 dan pada variabel kemampuan perencanaan karir sebesar 0,873. Analisis data dengan menggunakan korelasi product moment dengan menggunakan SPSS versi 25.Hasil penelitian menunjukkan bahwa terdapat hubungan positif dan signifikan antara kecerdasan emosional dengan kemampuan perencanaan karir siswa kelas XI TKJ SMK PGRi 1 Palimanan dengan koefisien korelasi sebesar 0,382 dengan (p<0,05). Tanda positif menunjukkan bahwa semakin tinggi kecerdasan emosional siswa, maka semakin tinggi kemampuan perencanaan karirnya, dan semakin rendah kecerdasan emosional siswa maka semakin rendah kemampuan perencanaan karirnya. Berdasarkan perhitungan dapat ditunjukkan bahwa sumbangan efektif kecerdasan emosional terhadap kemampuan perencanaan karir adalah sebesar 14,6% sedangkan sumbangan sebesar 85,4 % berasal dari faktor lain.
IMPLEMENTASI KURIKULUM MADRASAH TSANAWIYAH (MTs) MELALUI PELAKSANAAN PENDIDIKAN PESANTREN DI MTs AL-ISHLAH GARAWANGI
Authors: Mumu Muzayyin Maq
Published: June 2024

Pendidikan sebagai proses penenuhan kebutuhan keilmuan seluruh peserta didik. Proses impelementasi pendidikan merupakan langkah dalam pemenuhan kebutuhan tersebut. Implementasi Kurikulum Madrasah Tsanawiyah (MTs) melalui Pelaksanaan Pendidikan Pesantren di MTs Al-Ishlah Garawangi Kecamatan Sumberjaya Kabupaten Majalengka merupakan salah satu proses dalam upaya kolaborasi kurikulum pendidikan dengan kurilulum pesantren. Tujuan penelitian ini adalah untuk deskripsikan proses impementasi kurikulum dari sisi desain, proses dan hasil. Penelitian ini menggunakan pendekatan kualitatif dengan subjek penelitian seluruh tenaga pendidik dan kependidikan MTs Al-Ishlah Garawangi Kecamatan Sumberjaya Kabupaten Majalengka. Hasil dari penelitian ini ialah berhubungan dengan pengembangan nilai-nilai pengembangan diri siswa terhadap penilaian norma keagamaan. Fokus implementasi pendidikan pesantren mengikuti pada program-program sekolah sebagaimana yang telah dirumuskan dalam standar kompetensi pada dokumen kurikulum madrasah. Proses implementasi pendidikan pesantren yang dikembangkan melalui program pengajaran terstruktur dan mengedepankan pengkajian nilai-nilai keagamaan.
IMPLEMENTASI MODEL DESA MIGRAN PRODUKTIF DI INDONESIA
Authors: Bambang Sudaryana
Published: June 2024

Tujuan utama dari penelitian ini adalah untuk menentukan model pengelolaan desa  yang mendukung penghentian pengiriman tenaga kerja Indonesia yang tidak terdidik ke luar negeri baik yang illegal maupun ilegal dan untuk menentukan strategi peningkatan kesejahteraan purna migrant dalam menata kehidupannya serta  strategi menata kelola desa yang penduduknya memiliki jiwa kewirausahaan .Studi ini diharapkan untuk menyelidiki bagaimana model pengelolaan desa ini dapat dijadikan digunakan oleh masyarakat desa untuk menata kehidupannya menjadi sejahtera. Gagasan ini muncul setelah menemukan bahwa praktik mengelola desa migrant tidak efektif.  Masyarakat desa Purna migrant hanya pulang untuk membelanjakan hasil kerjanya untuk pola yang konsumtif, bukan untuk investasi atau berwirausaha. Eksperimen dilakukan 1 (satu) tahun pada tahun 2019, untuk menentukan dampak implementasi model Desa migrant produktif. Sampel penelitian dilakukan terdiri dari 80 purna Migrant  di Desa Kenanga Kecamatan Sindang Kabupaten Indramayu
PENGEMBANGAN USAHA BUDIDAYA IKAN BANDENG (CHANOS CHANOS FROSKAL) MELALUI PENYULUHAN FARTIFATIF DI DESA KALISAPU GUNUNGJATI KABUPATEN CIREBON
Authors: Eulis Henda  , Asep Kostajaya  , Mustar Gowa
Published: June 2024

Ikan Bandeng (Chanos chanos Forskal) merupakan salah satu komoditas ekonomis penting diantara spesies ikan budidaya lain. Kecamatan Gunungjati merupakan salah satu wilayah pesisir yang memiliki potensi perikanan tambak. Kegiatan usaha budidaya bandeng konsumsi merupakan salah satu mata pencaharian bagi penduduk. Tujuan dari penelitian ini adalah untuk mengetahui pengembangan usaha budidaya ikan bandeng di Desa Kalisapu, Kecamatan Gunungjati Kabuapten Cirebon.Metode yang digunakan adalah wawancara, observasi dan studi pustaka.  Hasil dari penelitian ini adalah Luas areal operasional untuk tambak bandeng yang ada di Kecamatan Gunungjati mencapai 111 ha dengan jumlah RTP 120 orang. Produksi yang dihasilkan setiap hektar bisa mencapai 300-400 kg dengan size 6-7 ekor/kg dengan harga jual Rp. 9.000-10.000/kg. Dari hasil perhitungan tersebut dapat diketahui nilai R/C ratio = 1,09. Dengan demikian usaha budidaya ikan bandeng masih layak walaupun nilai keuntungannya masih rendah. Untuk itu perlu pengembangan usaha perlu ditingkatkan dalam manajeman usahanya. Kelayakan usaha ikan bandeng dengan dengan nilai Payback period adalah 2,66 peride artinya investasi yang masukan dalam usaha tersebut dapat kembali setelah 3 kali siklus usaha. Dari hasil perhitungan dapat diketahui bahwa usaha budidaya ikan bandeng akan mendapatkan keuntungan apabila titik maksimal lebih dari BEP rupiah sebesar Rp. 2.072.368,42  atau BEP unit sebesar 231,61  kg/siklus.
MERDEKA BELAJAR DI UNIVERSITAS NAHDLATUL ULAMA CIREBON
Authors: Deddy Hendriady  , Ardi Ade Zaenudin , Ardi Hanafiah , Ardi Hendi Suhendraya
Published: June 2024

Merdeka Belajar adalah program yang dicanangkan pemerintah dalam bidang pendidikan untuk meningkatkan kualitas mutu. sehingga berimplikasi pada peningkatan kualitas hidup manusia Indonesia. Program ini berorientasi pada lahirnya inovasi dan adaptif terhadap keragaman potensi dan kemajuan. Program ini menyasar seluruh jenjang pendidikan, mulai dari tingkat dasar sampai perguruan tinggi. Penelitian ini bertujuan untuk memotret implementasi program Merdeka Belajar di Universitas Nahdlatul Ulama Cirebon. Penelitian ini menggunakan metode studi kasus dengan pengumpulan data melalui wawancara, observasi, dan dokumentasi yang berkaitan dengan program Merdeka Belajar. Berdasarkan hasil penelitian, Universitas Nahdlatul Ulama Cirebon sudah berupaya untuk mengimplementasikan progam Merdeka Belajar yang dicanangkan pemerintah dengan melakukan beberapa inovasi membangun kolaborasi dengan berbagai pihak di luar kampus dalam rangka memenuhi tuntutan dunia usaha dan dunia industri dengan harapan eksistensi Universitas Nahdlatul Ulama Cirebon berdampak positif bagi masyarakat luas
STUDI DESKRIPTIF PENERAPAN STUDENT TEAMS ACHIEVEMENT DIVISIONS (STAD) PADA PEMBELAJARAN IPA DI SDN 2 MUNJUL KABUPATEN CIREBON
Authors: Nazwa Melinda Septian  , Sri Hastuti
Published: June 2024

Guru sebagai pusat pembelajaran saat ini mulai diubah menjadi peserta didik menjadi pusat pengetahuan dan pembelajaran (student centered learning). Untuk itu, metode pembelajaran cooperative learning model student teams achievement division (STAD) dapat terapakan untuk meningkatkan partisipasi secara aktif dalam pembelajaran. Metode penelitian ini adalah deskriptif kualitatif. Pengumpulan data dilakukan melalui observasi dan wawancara. Hasil temuan penelitian ini menunjukkan bahwa guru menjadi fasilitator dalam pembelajaran dan siswa belajar melalui pengalaman secara langsung, mengarahkan siswa untuk mencari dan menemukan sendiri bagaimana penggolongan hewan tersebut dengan objek yang nyata