bluuebunny/crossref_metadata_2025 huggingface dataset:
Parental stress parameter difference after caring for congenital adrenal hyperplasia children with genital ambiguity
Authors: Saktini Fanti , Fitrikasari Alifiati , Asikin Hang Gunawan , Noerhidajati Elly , Utari Agustini
Published: November 2023

Introduction:

Congenital adrenal hyperplasia (CAH) disrupts cortisol biosynthesis, which may cause genital ambiguity in females. Caring for children with genital ambiguity creates parental distress. Common stress parameters include biological (e.g., serotonin cortisol) and psychological (e.g., Depression, Anxiety, and Stress Scale [DASS] scores). This study elaborated parental stress parameter differences among parents of CAH children with and without genital ambiguity.

Methods:

This cross-sectional study included 34 fathers and 44 mothers of children with CAH. All participants agreed to fill in the DASS-42 and socioeconomic questionnaire. Morning serum serotonin and cortisol samples were examined using the enzyme-linked immune-absorbent assay technique.

Results:

The median (minimum–maximum) value of serotonin concentration was lower in fathers compared to mothers (281.18 [78.44–122.91] ng/ml vs. 399.78 [122.91–1050.0] ng/ml, P = 0.11); in parents of children with genital ambiguity (292.22 [78.44–1050.00] ng/ml vs. 426.71 [150.78–1050.00] ng/ml, P = 0.01); and in parents of children with a diagnosis time <1 year (225.00 [93.41–570.33] ng/ml vs. 371.815 [78.44–1050.00] ng/ml, P = 0.046). Higher cortisol concentration was observed in parents of children with diagnosis time <1 year (78.65 [50.89–126.89] ng/ml vs. 63.33 [6.14–283.67] ng/ml, P = 0.046). The proportion of depression was 24.4%, anxiety 45.1%, and stress 21.8%.

Conclusion:

Fathers, parents of children with genital ambiguity, and being recently diagnosed had lower serum serotonin levels. Parents of recently diagnosed children had higher cortisol levels. Anxiety was more common than depression and stress.
Beta-Hydroxy-Beta-Methylbutyrate Supplementation Preserves Fat-Free Mass in Collegiate Boxers during Acute Body Mass Loss
Authors: Chang Chen-Kang , Kao Shih-Yen , Wang Chung-Yuan
Published: November 2023

Acute body mass loss before competitions in combat sports usually leads to loss in fat-free mass. Beta-hydroxy-beta-methylbutyrate (HMB) has been shown to increase skeletal muscle mass and muscle strength in various muscle wasting conditions. This study investigated the effect of HMB supplementation on body composition and sport-specific performance in well-trained boxers consuming a hypocaloric diet. Twelve male college boxers were divided into the HMB and placebo (PLA) groups using a body weight-matched single-blind parallel design. The study comprised a 6-day weight loss period (days 1–6), followed by a 3-day competition period (days 7–9). The participants in both the groups consumed 16 kcal/kg/day, including 1.6–1.7 g/kg of carbohydrates, 1.2–1.3 g/kg of protein, and 0.45–0.5 g/kg of fat during the 9-day period. The HMB group consumed 3 g/day HMB. Body composition measurement, isometric mid-thigh pull (IMTP), and a simulated boxing match were performed at baseline and on days 7, 8, and 9. Fasting blood samples were collected on the day before day 1 and on days 7, 8, and 9. Body mass was significantly decreased after the 6-day weight loss period (HMB group: baseline: 69.4 ± 11.2 kg, day 7: 67.1 ± 11.2 kg; PLA group: baseline: 68.6 ± 12.1 kg, day 7: 65.7 ± 11.5 kg, P < 0.05) while it was unchanged on the 3-day competition period in both the groups. Fat-free mass in the HMB group was maintained throughout the 9-day period (baseline: 56.7 ± 9.3 kg, day 7: 56.3 ± 8.7 kg, day 9: 55.8 ± 9.5 kg) whereas it significantly decreased on days 7 and 9 compared to the baseline in the PLA group (baseline: 55.2 ± 6.4 kg, day 7: 54.1 ± 6.6 kg, day 9: 54.0 ± 6.6 kg, P < 0.05). In the PLA group, the average and maximal heart rates in round 1 and the average heart rate in round 2 on days 8 and 9 were significantly lower than those at baseline, while these parameters were unchanged in the HMB group. The maximal force and the rate of force development in the IMTP remained unchanged among the different timepoints in both the groups. The blood biochemical parameters were similar at any timepoint between the PLA and HMB groups. HMB supplementation during acute weight loss may preserve fat-free mass and maintain heart rate response in subsequent simulated matches in well-trained boxers. In addition, HMB supplementation had a nonsignificant effect on glucose, fat, and protein metabolism during energy restriction.
Long Non-Coding RNA LINC00565 Regulates ADAM19 Expression through Sponging MicroRNA-532-3p, Thereby Facilitating Clear Cell Renal Cell Carcinoma Progression
Authors: Meng Bin , Wang Pengfei , Zhao Chaofei , Yin Guangwei , Meng Xin , Li Lin , Cai Shengyong , Yan Chengquan
Published: November 2023

Proven by publications, long non-coding RNAs (lncRNAs) play critical roles in the development of clear cell renal cell carcinoma (ccRCC). Although lncRNA LINC00565 has been implicated in the progression of various cancers, its biological effects on ccRCC remain unknown. This study aimed to investigate the biological functions of LINC00565, as well as its potential mechanism in ccRCC. Here, the expression data of mature microRNAs (miRNAs) (normal: 71, tumor: 545), messenger RNAs (mRNAs), and lncRNAs (normal: 72, tumor: 539) of ccRCC were acquired from The Cancer Genome Atlas (TCGA) database and subjected to differential expression analysis. Quantitative reverse transcriptase polymerase chain reaction analyzed the expression levels of LINC00565, miR-532-3p, and ADAM19 mRNA. TCGA database, dual-luciferase report detection, and Argonaute 2 RNA immunoprecipitation were utilized to confirm the relationships between LINC00565 and miR-532-3p and between miR-532-3p and ADAM19, respectively. The progression of ccRCC cells was determined via CCK-8, colony formation, scratch healing, and transwell assays. Western blot was applied to detect the protein levels of epithelial-mesenchymal transition markers and ADAM19. We herein suggested that LINC00565 was prominently upregulated in ccRCC tissues and cells. Knockdown of LINC00565 repressed cell progression. We further predicted and validated miR-532-3p as a target of LINC00565, and miR-532-3p could target ADAM19. Knockdown of LINC00565 resulted in ADAM19 level downregulation in ccRCC cells and suppressed miR-532-3p could restore ADAM19 level. Thus, the three RNAs constructed a ceRNA network. Overexpressed ADAM19 could eliminate the anticancer effects caused by knocking down LINC00565 on ccRCC cells. In conclusion, LINC00565 upregulated ADAM19 via absorbing miR-532-3p, thereby facilitating the progression of ccRCC cells.
Role of detailed information about anaesthesia during PAC to reduce patient’s anxiety during the perioperative period
Authors: Padsala Krishna , Patel Harsha , Nakum Rajesh , Sojitra Nalin P.
Published: November 2023

Background:

Perioperative anxiety may adversely influence anaesthetic induction and patient’s recovery. Pharmacological interventions include the use of narcotics, sedatives and anxiolytics. However, such drug interventions are typically accompanied by adverse reactions. Perioperative anxiety experienced by patients can be significantly diminished through the provision of comprehensive information regarding the anaesthesia procedure, surgical procedure and perioperative events during the pre-anaesthetic assessment conducted in an outpatient consultation clinic.

Aims:

This prospective study was conducted to assess the impact of providing comprehensive information on alleviating patient anxiety throughout the perioperative period.

Materials and Methods:

This prospective observational study was conducted on 60 patients to assess patient’s perioperative anxiety for anaesthesia and surgery. All study participants were asked to mark their pre-operative anxiety on the Visual Analogue Scale-Anxiety (VAS-A) and asked to fill the questionnaire of Amsterdam Pre-operative Anxiety and Information Scale (APAIS).

Results:

During the pre-information evaluation, patient’s mean VAS-A score was 4.73 ± 2.75 which decreased to 3.65 ± 2.53 in post-information evaluation (P = 0.027). The overall APAIS score during pre-information and post-information evaluation was 17.4 ± 8.06 and 13.18 ± 7.06 (P = 0.002). The mean APAIS score for anaesthesia and surgery during the pre-information evaluation was 2.67 ± 1.46 and 3.13 ± 1.54, respectively, which decreased to 2.04 ± 1.18 and 2.35 ± 1.30, respectively, in post-information evaluation. This difference in APAIS score evaluation during pre-information and post-information evaluation for anaesthesia (P = 0.0105) and surgery (P = 0.003) was statistically significant.

Conclusion:

Perioperative anxiety experienced by patients can be effectively mitigated by providing comprehensive information pertaining to anaesthesia procedures, surgical procedures and perioperative events during the pre-anaesthetic assessment conducted within an outpatient consultation clinic.
Simulation-based training in central venous catheterization for first-year postgraduate students: A prospective study
Authors: Kaur Haramritpal , Kaur Sarabjot , Singh Amandeep , Grover Urvashi , Maheshwari Chandni , Chawla Sumitpal Singh
Published: November 2023

Background:

The current model of procedure training involves lectures, seminars, observations and personalised education in small groups or by watching videos on digital platforms. Central venous catheterisation (CVC) is an important skill; however, its training largely remains unstructured. There is a need of protocol-based uniform training policy.

Aims:

The aims and objectives of the study are to prepare and implement simulation-based CVC training module for the 1st year post-graduate students.

Materials and Methods:

After approval from the institutional ethical committee, 1st year post-graduate students of anaesthesia, medicine and surgery were enroled. Training modules and questionnaires were prepared with discussions amongst faculty. Students’ baseline knowledge regarding the CVC was noted on mannequins along with self-reported confidence. After that, they were subjected to training module. Students repeat knowledge and confidence regarding CVC were noted. In the next few months, procedures performed by post-graduate students were directly observed and rated. Students as well as faculty feedback regarding this teaching module was also collected.

Results:

Training module was associated with a statistically significant increase in knowledge and self-reported confidence regarding the knowledge and skill of CVC (P < 0.05). Most of the students and faculty agreed regarding the training module utility.

Conclusions:

A structured simulation module for CVC helped to improve students’ knowledge and confidence about the CVC skill. The module was well accepted by both faculty and students.
A noisy airway: Varying causes for upper airway obstruction in a child
Authors: Srinivasan Ranjini , Krishna Sushma , Dinakar Chitra , Pratibha CB
Published: November 2023

Noisy breathing is a common symptom in infancy and childhood. It can sometimes be intimidating to the parents and a diagnostic challenge to the treating physician. Causes for a noisy airway include congenital and acquired conditions. They can vary in etiology from self-resolving conditions like laryngomalacia to more sinister entities like malignant tumors. We present a 3-year-old girl who presented with noisy breathing since the age of 6months associated with poor weight gain and chest deformity. Due to persistence of her symptoms, she underwent upper airway evaluation at different time points and was found to have varied causes for her noisy respiration that included airway malacia, pharyngeal wall inspiratory collapse and later adenoidal hypertrophy which was complicated by symptoms suggestive of obstructive sleep apnea. The above three conditions are known to co-exist and can manifest at varied points of time. Since it is unusual to encounter varied causes of upper airway obstruction in the same patient, this case is being presented for its rarity and to highlight the importance of evaluating the upper airway repeatedly if symptoms are persistent, variable or progressive.
A Case of Ticagrelor-Induced Seizure
Authors: Selvi Fatih , Bedel Cihan , Baltacioglu Bora , Yıldız Günay
Published: November 2023

Ticagrelor is available as an oral antiplatelet agent that can bind reversibly to the adenosine diphosphate receptor P2Y12 on platelets without first having to be activated. Main side effects such as dizziness, bleeding gums, nausea in common, difficulty in speaking, fever, and change in mental status are rare. Herein, we report a patient who had seizures after the usage of ticagrelor.
Successful Bail Out of Rotablator Driveshaft Fracture Due to Severe Calcified Lesion and Proximal Tortuosity
Authors: Uehara Hiroki , Okuyama Masaki , Oe Yutaro , Yoshimura Takaki , Gunji Takahiro
Published: November 2023

A 59-year-old male dialysis patient with a history of coronary artery bypass graft surgery underwent percutaneous coronary intervention of a right coronary artery with a severely calcified lesion. While debulking calcification using a Rotablator, the driveshaft was suddenly fractured. We attempted to move a child-in-mother catheter closer and across a second floppy wire and we dilated a 2.0-mm noncompliant balloon to trap the driveshaft, which we then removed, and restarted the intervention.
Point of Care Tests
Authors: Sharma Anuradha , Chourasia Ekta , Goswami Shubham
Published: November 2023

Background:

Point of care tests provide rapid information about the patient's condition, with a turnaround time of 15 min. During the COVID-19 pandemic, many such point of care tests were developed, to aid in the rapid diagnosis of SARS-Cov-2 infection.

Aim:

To describe and synthesize the available literature on point of care tests for diagnosis of SARS-CoV-2.

Methodology: This narrative review was done through online literature search, using Google Scholar and PubMed.

Result:

There were 51 point of care tests for diagnosis of SARS-CoV-2 which were validated using different samples, such as such as nasopharyngeal swabs(42), oropharyngeal and naso-pharyngealswabs(2), oropharyngeal swab in VTM(1) nasal swabs(5) and throat swab(1).

Conclusion:

There was global developement of point of care tests on a war footing. The Indian states of Delhi, Maharashtra, Gujarat, Uttar Pradesh, Tamil Nadu, Karnataka, Haryana, Rajasthan, Kerala, Himachal Pradesh, Goa and Uttarakhand, were in the forefront of these developments, as also the USA, Belgium, Taiwan, Korea and South Korea.
Abnormal Resting Myocardial Contrast Echocardiographic Uptake
Authors: Jakulla Roopesh Sai , Gunta Satya Preetham , López-Candales Angel
Published: November 2023

Acute coronary syndromes (ACSs) present most frequently with chest pain, but angina equivalents such as dyspnea, diaphoresis, and fatigue are not uncommon. Atypical presentations are especially seen in women, the elderly, and diabetics. Cardiac evaluation using a transthoracic echocardiogram is almost always done before or immediately after someone undergoes left heart catheterization for ACS. It provides information valuable information regarding wall motion, left ventricular systolic function, diastolic function, right ventricular involvement, pulmonary pressures, incidental valvular disease, pericardial fluid, or any other unsuspected abnormality. We describe a novel case where an atypical presentation of ACS was suspected based on the lack of intravenous contrast administered, to enhance endocardial border resolution. The use of contrast during echocardiography has been used during stress protocols to assess microcirculation during perfusion assessment studies. However, we described a reduced uptake during the acquisition of resting myocardial echocardiogram images and it was very useful to direct therapy.
A New Era of Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated Protein 9 Gene Editing Technology in Cardiovascular Diseases
Authors: Kumar Rahul , Singh Sushil Kumar , Kumar Sarvesh , Tewarson Vivek , Hakim Mohammad Zeeshan , Kaushik Karan , Kumar Satish , Kumar Bhupendra
Published: November 2023

Cardiovascular diseases (CVDs) remain major causes of global mortality in the world. Genetic approaches have succeeded in the discovery of the molecular basis of an increasing number of cardiac diseases. Genome-editing strategies are one of the most effective methods for assisting therapeutic approaches. Potential therapeutic methods of correcting disease-causing mutations or of knocking out specific genes as approaches for the prevention of CVDs have gained substantial attention using genome-editing techniques. Recently, the clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) system has become the most widely used genome-editing technology in molecular biology due to its benefits such as simple design, high efficiency, good repeatability, short cycle, and cost-effectiveness. In the present review, we discuss the possibilities of applying the CRISPR/Cas9 genome-editing tool in the CVDs.
The Overall Prevalence and Main Determinants of Prolonged Mechanical Ventilation in Patients Undergoing Coronary Artery Bypass Grafting
Authors: Shahsanaei Farzad , Behrooj Soudabeh , Petrudi Nima Rahimi , Khajehbahrami Fahim
Published: November 2023

Background:

Although respiratory support is necessary to maintain hemodynamic stability in patients undergoing major surgeries, prolonging the time of mechanical ventilation is considered a major complication following these procedures. The identification of potential factors related to this phenomenon should be identified. In the present systematic review, we first assess the pooled prevalence of prolonged mechanical ventilation (PMV) in patients undergoing coronary artery bypass grafting (CABG) surgery and also determine the main predictors for PMV by deeply reviewing the literature.

Materials and Methods:

The manuscript databases including Medline, Web of Knowledge, Google Scholar, Scopus, and Cochrane were deeply searched by the two blinded investigators for all eligible studies based on the relevant keywords. Based on the titles and abstracts, 88 records were initially included and of those, 15 articles were eligible for the final analysis.

Results:

The pooled prevalence of PMV in the studies that defined PMV as ventilation >24 h was 6.5% (95% confidence interval [CI]: 4.1%–10.2%) and in the studies, PMV as ventilation >48 h was 2.8% (95% CI: 1.7%–4.7%). Demographics (gender and advanced age), obesity, underlying comorbidities (hypertension, chronic kidney disease, cerebrovascular accident, high New York Heart Association class, history of chronic obstructive pulmonary disease, and history of acute coronary syndrome), emergency surgery, intraoperative characteristics (needing intra-aortic balloon pump, increased peak airway pressure, using cardiopulmonary bypass, the type of dose of anesthetics, cross-clamp time, increased units of blood transfusion, occurring cardiac ischemic events within an operation, fluid imbalance, and some anastomoses), and some postoperative outcome such as lowering O2 saturation, sequential organ failure assessment score, inotrope use, pleural effusion, delirium, and prolonged intensive care unit stay were found to be the main determinants for PMV.

Conclusion:

Depending on the definition of PMV, the prevalence of PMV varied from 1.7% to 10.2%. Various factors before, during, and after surgery are the predictors of PMV in these patients, which can be used to design new scoring systems to predict it.
Quality of life assessment in children and their caregivers suffering from allergic rhinitis and/or asthma
Authors: Wadhawan Pallavi , Gupta Neeraj , Srivastava Prakriti , Sachdev Anil
Published: November 2023

INTRODUCTION:

Asthma and allergic rhinitis (AR) are among the most prevalent diseases worldwide and they frequently persist throughout the life. These have significant effect on physical, financial, and mental wellbeing of patients and caregivers. There have been few attempts previously, assessing the quality of life (QOL) in affected families suffering from these diseases. However, the data from developing countries are scarce. QOL assessment in children and caregivers of patients suffering can help in symptomatic management and provide inputs for the better utilization of resources to achieve optimal treatment.

MATERIALS AND METHODS:

Patient and caregiver QOLs were ascertained using Mini Pediatric Asthma QOL Questionnaire and Pediatric Asthma Caregiver's QOL Questionnaire, respectively, in the study and correlated with disease severity and chronicity using the parametric and nonparametric statistical tools.

RESULTS:

There were 246 pairs of children diagnosed with asthma and/or AR and their caregivers attending the pediatric allergy and asthma clinic. Symptom score, emotional domain, and activity limitation in children did not validate a statistically significant difference in QOL in the various grades of AR/asthma/AR with asthma (P = 0.632) (P = 0.772) (P = 0.496) (P = 0.918) (P = 0.384) and (P = 0.561), respectively. In addition, there was no significant correlation between the severity of asthma and caregiver emotional disturbance (P = 0.594) or caregiver activity limitation (P = 0.446).

CONCLUSIONS:

QOL in children and caregivers where children are suffering from either AR or asthma, or both has not shown any significant difference as per the disease severity or chronicity in various domains. There was no significant difference in QOL noted as per the change in age group, gender of patients, or education status of caregivers.
Fungal sensitization and its impact on asthma control – A prospective study at allergy clinic
Authors: Jain Anil Kumar , Kumar Anil
Published: November 2023

BACKGROUND:

Various factors are involved in poorly controlled asthma despite adequate medication and proper inhalation techniques. Mold sensitivity has been associated with increased rates of hospital and intensive care admissions in adults. The fungal sensitization with severe asthma has been coined to describe fungal-sensitized patients with treatment-resistant asthma. The objective of this study was to compare asthma control between fungal- and nonfungal-sensitized (NFS) asthma patients.

MATERIALS AND METHODS:

Fifty-six cases of asthma were included over a period of 12 months in this prospective study. Data were captured using a proforma. Skin prick test was done as per standard protocol in all patients and a control assessment was done after 6–8 weeks of treatment as per GINA guidelines using Asthma Control Test (ACT) score. Data were analyzed using SPSS version 24.0.

RESULTS:

Out of 56 enrolled, 32.1% were fungal sensitized and 55.4% to NFS. Seven (12.5%) patients did not have clinically significant reactions. Maximum sensitization was found with Aspergillus spp. but no sensitization with Epicoccum and Cladosporium. Asthma was found to be poorly controlled in 77.8% of the fungal-sensitized group with a mean ACT score of 17.7 ± 1.8 as compared to 6.5% in the NFS group with mean ACT of 21.35 ± 1.6, respectively (P < 0.0001).

CONCLUSION:

Fungal sensitization was associated with poorly controlled asthma despite adequate medications and education. Early diagnosis and treatment in these patients with antifungals may improve quality of life, reduce exacerbations, and control of the primary disease.
Asthma management with the help of digital therapeutics: Review of clinical trials
Authors: Wadgaonkar Madhumangesh , Aggarwal Aditi , Solanki Goutam Singh
Published: November 2023

Digital therapeutics has emerged as a promising approach to manage chronic health conditions, including asthma. With the help of digital inhalers, mobile apps, and monitoring devices, patients can track their symptoms in real time and access personalized treatment plans remotely. Telemedicine and telemonitoring asthma have enabled health-care providers to monitor patient progress continuously while reducing the need for frequent office visits. Digital inhalers are one such example, providing patients with a complex therapeutic modality to self-administer. One such example is Propeller's digital platform helps asthma patients and their health-care providers record and monitor medication usage, review symptoms, and receive personalized interventions. A literature review was conducted to identify clinical trials reporting the use of digital tools for improving asthma outcomes, which showed that there are only monitoring tools available to improve asthma management through digital therapeutics at present. For example monitoring of adherance, asthma outcomes measurement. However, advancements in technology hold great potential for providing more comprehensive care by integrating data from multiple sources such as wearable sensors or electronic medical records into a single platform that could support better decision-making regarding patient care. The field of digital therapeutics is still evolving, but it holds immense promise for revolutionizing how we manage complex health conditions like asthma by empowering patients with effective tools that allow them to take control of their condition proactively.
Сепаратрисные отображения в быстро-медленных гамильтоновых системах
Authors: Bolotin Sergey Vladimirovich
Published: November 2023

Получены явные формулы для сепаратрисного отображения многомерной быстро-медленной гамильтоновой системы. Это отображение используется для частичного распространения на многомерный случай результатов А.И. Нейштадта о скачках адиабатических инвариантов на сепаратрисе.
К проблеме концентрации энергии
Authors: Golubyatnikov Aleksandr Nikolaevich , Ukrainskii Dmitrii Vladimirovich
Published: November 2023

Обсуждается известная проблема концентрации энергии, обратная к задачам о сильном взрыве или расширяющемся поршне. На ряде физических примеров показано, что при определенных условиях и участвующих в процессе фокусировки силах можно добиться концентрации любой величины энергии. Прежде всего речь идет о силе тяжести и ее проявлении в задачах теории относительности с учетом вязкости и теплопроводности.
Напряженное состояние упругого полупространства в условиях дискретного контакта
Authors: Goryacheva Irina Georgievna , Yakovenko Anastasiya Aleksandrovna
Published: November 2023

Исследовано контактное взаимодействие с упругим полупространством периодической системы осесимметричных штампов с двумя высотными уровнями при отсутствии сил трения. Решение задачи строится с помощью метода локализации. Получены аналитические выражения, определяющие контактные характеристики взаимодействия (радиус пятен контакта и распределение контактных давлений), а также компоненты тензора внутренних напряжений на осях симметрии штампов обоих уровней. Проанализировано влияние формы контактирующей поверхности штампов, которая описывается степенной функцией (с произвольным целым показателем), и пространственного расположения штампов на контактные характеристики и напряженное состояние упругого полупространства.
Продольно-крутильные волны в нелинейно-упругих стержнях
Authors: Kulikovskii Andrey Gennadievich , Chugainova Anna Pavlovna
Published: November 2023

Ранее была получена система гиперболических уравнений четвертого порядка, описывающая продольно-крутильные длинные нелинейные волны малой амплитуды, распространяющиеся по упругому стержню. В каждую сторону по стержню распространяются волны двух типов: быстрые и медленные. В предлагаемой работе, исходя из упомянутой системы уравнений, получена гиперболическая система второго порядка, описывающая продольно-крутильные волны, распространяющиеся с близкими скоростями вдоль стержня в одном направлении. Предполагается, что волны, распространяющиеся в противоположном направлении вдоль стержня, имеют пренебрежимо малую амплитуду. Показано, что изменение величин в простых и ударных волнах, описываемых системой уравнений второго порядка, полученной в данной работе, в точности совпадает с изменением величин в соответствующих волнах, описываемых исходной системой уравнений четвертого порядка, а скорости этих волн близки. Исследованы изменение величин в простых волнах (волнах Римана) и условия их опрокидывания.
Road Vehicles - Symbols for Controls, Indicators, and Tell-Tales
Authors:   Controls and Displays Standards Committee
Published: November 2023

This SAE Standard specifies symbols (i.e. conventional signs) for use on controls, indicators, and tell-tales applying to passenger cars, light and heavy commercial vehicles, and buses, to ensure identification and facilitate use.

It also indicates the colors of possible optical tell-tales, which inform the driver of either correct operation or malfunctioning of the related devices.
Accelerated Exposure of Automotive Interior Trim Components Using a Controlled Irradiance Xenon-Arc Apparatus
Authors:   Textile and Flexible Plastics Committee
Published: November 2023

This test method specifies the operating procedures for a controlled-irradiance, xenon-arc apparatus used for the accelerated exposure of various automotive interior trim components.

Test duration, as well as any exceptions to the specimen preparation and performance evaluation procedures contained in this document, are covered in material specifications of the different automotive manufacturers.

Any deviation to this test method, such as the use of optical filter combinations, is to be agreed upon by contractual parties.
Depois do descarte
Authors: Reis Tainá
Published: November 2023

O objetivo deste artigo é apresentar, a partir do conceito de ethos barroco, as estratégias de resistência dos cortadores de cana adoecidos e descartados. As condições de trabalho no corte de cana de açúcar resultam no desgaste da força física e mental dos trabalhadores, que adoecem em decorrência do trabalho, perdem a capacidade laboral e são descartados. A pesquisa qualitativa realizada no Vale do Jequitinhonha/MG mostrou que os trabalhadores carregam em seus corpos, relações e subjetividade as consequências dessa atividade. Uma nova sociabilidade tecida é atravessada pela vergonha, pela destinação à morte social, pela fratura nas relações, processos que não são vivenciados pelos sujeitos passivamente. Aponta-se a Festa de Nossa Senhora do Rosário como uma expressão de resistência.
As torcedoras e o torcer
Authors: Andrade Marianna Castellano Barcelos de
Published: November 2023

O presente artigo pretende discutir as inserções e as experiências das mulheres nas torcidas organizadas de futebol na contemporaneidade. A reflexão toma como base a etnografia realizada entre torcedoras que compõem Os Gaviões da Fiel, a primeira torcida organizada de São Paulo. A discussão que se segue tem as mulheres como foco e se utiliza do conceito de gênero como uma categoria útil para a análise das desigualdades entre homens e mulheres praticadas e construídas historicamente nos diversos espaços de socialização da agremiação. O texto busca problematizar também Os Gaviões da Fiel como uma torcida organizada possuidora de um ethos progressista, sobretudo no senso comum, mas que ainda assim, mantém dentro de seus domínios um certo conservadorismo de gênero.
Mulheres trans no YouTube:
Authors: De Oliveira Fagundes Nagel
Published: November 2023

O referido artigo visou identificar os perfis de mulheres trans com maior visibilidade e projeção no YouTube, bem como a atenção e contratação de marcas e empresas que as buscam com o objetivo de parcerias. Desde a pesquisa de Ávila (2014) sobre transmasculinidades, o uso e adesão de usuários e usuárias trans na plataforma tem crescido expressivamente. À vista disso, novas questões têm surgido para pensar os usos das mídias digitais por essa população. A partir da crescente profissionalização das plataformas com a produção e a monetização de conteúdos digitais e da aceitação dos/das digitais influencers e youtubers, pretendeu-se refletir os marcadores sociais que impulsionam e/ou dificultam a visibilidade das identidades trans nesse espaço.
 
Palavras-chave: Mulheres trans; Youtubers; Mídias Sociais; Marcadores sociais da diferença.
Desafios e possibilidades do ensino de política no Ensino Médio em Sociologia
Authors: Ferreira Ana Paula
Published: November 2023

São diversos os entraves que dificultam o trabalho de política no Ensino Médio em Sociologia. Entretanto, para além de um panorama de denúncia da realidade, é objetivo desse trabalho apresentar possibilidades de modo que um tema tão importante esteja presente na formação cidadã, na defesa de uma sociedade mais democrática e com mais justiça social. Para esse intento, há tanto uma pesquisa bibliográfica quanto de utilização de fontes primárias, leis e currículo para o Ensino Médio, buscando nesses referenciais um apoio para docentes empreenderem na jornada da abordagem desse assunto.
Os filmes nos livros didáticos de sociologia para o Ensino Médio
Authors: Manoel Neto Armando
Published: November 2023

Este artigo propõe uma análise dos filmes indicados pelos livros didáticos de Sociologia escolhidos pelo Programa Nacional do Livro Didático (PNLD) de 2018/2020. Por meio de uma metodologia baseada em aspectos quantitativos da escolha destes filmes,  bem como a divisão entre os gêneros documentário ou ficção, foi possível estabelecer uma análise comparativa dos livros didáticos de sociologia para o Ensino Médio à luz da sociologia do conhecimento (Berger e Luckmann, 2014). O trabalho evidencia como as obras cinematográficas indicadas revelam especificidades do uso pedagógico do cinema no Ensino Médio. Matéria que fundamenta uma série de enquadramentos sugeridos ao final do texto para pensar o uso do cinema no ensino de sociologia.
Opinions of Faculty Members on the Effects of Using Social Media in Higher Education
Authors: Gencel Nurgun , Elmabaredy Ahmed , Semerci Çetin
Published: November 2023

This study aims to evaluate the opinions of faculty members about the effects of social media in education. The research was carried out as a qualitative study, and phenomenological design was used in the study. We selected a total of 36 faculty members to participate in an interview about their perceptions of social media effects on education. The results showed that most faculty members think that social media is an effective educational tool. In the context of the positive aspects, the role of social media in higher education is indicated as a support tool, a follow-up tool for educational activities, an entertaining platform, communication tool, resource, learning management tool and a guide. According to the findings, more than half of the academics think that the role of social media in education is positive. The study predicts that social media will have different roles in future education with the increasing number of users every day.
Correlates of Social Anxiety and Internet Addiction of Higher Education Students
Authors: Omoyemiju Michael Adeniyi , Omotosho Idowu Mujidat
Published: November 2023

The research examined the spread of internet addiction among tertiary institution students in Osun State and examine the connection between social anxiety and internet addiction. The research used descriptive survey research methodology. A sample of 1,430 students were picked to be involved in the research using multi-stage sampling methodology. Information were gathered using an instrument titled ″Social Anxiety and Internet Addiction Questionnaire (SAIAQ). Information gathered were analyzed using descriptive and inferential statistics. Specifically, research questions one, two and three were answered using percentages and frequency counts. Research hypotheses one, two and four were tested using Pearson product moment correlation while hypotheses three, five and six were tested using ordinal logistic regression, multiple regression analysis respectively. The outcome indicated that majority of participants (56.78%) exhibited little degree of internet addiction, while 23.63% and 15.01% exhibited moderate and severe levels of internet addiction respectively. The research also revealed a significant positive relationship between social anxiety and internet addiction among the students (r=0.261, p=0.000). The research inferred that social anxiety is potent factor that could trigger internet addiction of students and exhibition of internet addiction would reduce more with students’ age.
EVALUATION OF PERIPHERAL AND CENTRAL ANALGESIC EFFICACIES OF
AYURVEDIC NEW FORMULATION FOR AMAVATA DISEASE IN ANIMAL MODEL
THROUGH WRITHING TEST AND TAIL -FLICK IMMERSION TEST IN
MICEMODEL- AN ANIMAL EXPERIMENTAL STUDY.
Authors: Tanushree Roy , Mradu Gupta
Published: November 2023

Background: Rheumatoid arthritis (RA) is a chronic inflammatory disorder, it is the most common persistent inflammatory arthritis, occurring throughout the world and in all ethnic groups. This is the most marked in those with severe diseases, with a reduction in expected lifespan by 8-15 years. Around 40% of RA pa-tients are registered disable within 3 years, around 80% are moderately to severely disables within 20 years, and 25% will require a large joint replacement. Functional capacity decreases most rapidly at the beginning of disease and the functional status of patients within their 1st year of RA is often predictive of long-term out-come(1).
Aim: In research field RA need more attention for deep research due to, firstly its unbearable symptoms and secondary complication and secondly in modern science there are medicines available for temporary manage-ment purpose but with lot of adverse reaction. RA is a non-curable disease, in Ayurveda, RA can be corelated with Amavata disease (Rheumatoid arthritis).
Methodology: In this present study It has been taken up to see the efficacy of new combined Ayurvedic formu-lation i,e combination of Stem of Asthishrinkhala (Cissus quadrangularis L), bulb of Sunthi (Zingiber offici-nale Roscoe) and bulb of Rasona (Allium sativum L) with (1:1:1) ration for better management with less side effects. This research firstly done on animal to evaluate central and peripheral activity of research drug, through Writhing Test and Tail -flick immersion test in Mice model.
Synthesis and physicochemical characterisation of the Ni(II) complex with 3- (4-chlorophenyl)-1H-pyrazole ligand
Authors:   University of Novi Sad, Faculty of Sciences, Serbia, Kostić Marijana S. , Radnović Nikola D. ,   University of Novi Sad, Faculty of Sciences, Serbia, Radović Ana ,   Accreditaion Body of Montenegro, Podgorica, Montenegro, Kočović David ,   Institute for Medicines and Medical Devices of Montenegro, Jaćimović Željko ,   University of Montenegro, Faculty of Metallurgy and Technology, Barta Holló Berta ,   University of Novi Sad, Faculty of Sciences, Serbia, Radanović Mirjana M. ,   University of Novi Sad, Faculty of Sciences, Serbia
Published: November 2023

The coordination properties of 3-(4-chlorophenyl)-1H-pyrazole (HL) was investigated and its complex with Ni(II) ion was synthesized. The structure of the ligand was proven using SC-XRD, while both the ligand and the complex were characterized by spectroscopic, and thermogravimetric measurements. The purity and composition of the complex were confirmed by PXRD, elemental analysis, and conductometric measurements. Besides, the search for CSD was made to establish the frequency of different coordination modes of similar compounds. It was found that monodentate coordination of the neutral ligand molecule or the exo-bidentate one in the case of the deprotonation of the pyrazole ring is possible. Based on the results obtained, the formula [Ni2(μ-L)2(OH)2(H2O)2]·2H2O and the bridging bidentate coordination of the monoanionic form of the ligand via nitrogen atoms of the pyrazole ring was suggested.
Կուտակային հեքիաթների և ծիսերգային բանահյուսության որոշ զուգահեռներ
Authors: Վարդանյան Նվարդ
Published: November 2023

Կուտակային (կումուլյատիվ) հեքիաթը հայկական բանահյուսության՝ մինչ օրս առավել քիչ ուսումնասիրված տեսակներից է: Որպես հեքիաթի ենթաժանր՝ կուտակային հեքիաթները առանձնացվում են՝ ելնելով դիպաշարերի ոչ թե բովանդակային, այլ կառուցվածքային հատկանիշներից: Ելակետը որոշակի կայուն կրկնություններով կուտակվող հյուսվածքն է, որը սյուժեի յուրաքանչյուր օղակում նոր բաղադրիչ է ներառում: Կուտակային նույնաբնույթ կառույց հատուկ է նաև ժողովրդական որոշ ծիսերգերի չափածո կառույցների, ուր մոտիվային կրկնությունները հուշում են ծագումնաբանական ընդհանրությունների մասին:

Հոդվածում միջտեքստային քննության են ենթարկվում մի շարք կուտակային հյուսվածքներ՝ հեքիաթներ ու երգեր: Քննության մեջ ներառել ենք նաև Հովհ.Թումանյանի մշակած և փոխադրած՝ կուտակային հյուսվածքների բարձրարվեստ մշակումները՝ համադրելով դրանք ժողովրդական տարբերակներին և ծիսերգային բանահյուսության այլ նմուշների: Դիտարկվում է կուտակային շղթայի զարգացման տրամաբանությունը՝ ծննդի և մահվան, արարման և քայքայման հաջորդական օղակներով, շղթայի ձևավորման տրամաբանությունը՝ ելնելով կենսանորոգման և կենսապտույտի տրամաբանությունից, որն առանցքային է նաև ամանորյա և հարսանեկան ծիսական բանահյուսության համար: Սրանով էլ պայմանավորվում է կուտակային հեքիաթների ծագումնաբանական ընդհանրությունը բարեկենդանյան և հարսանեկան ծիսական բնագրերին և պարզվում հարսի, փեսայի և պսակի մոտիվների առատությունը քննարկվող կուտակային կառույցներում:
ՀՀ անվտանգության ապահովման և ազգային շահերի հստակեցման հիմնախնդիրները փոխակերպվող աշխարհում դաշնակցային հարաբերությունների նոր հարացույցների ներքո
Authors: Ղևոնդյան Ալեն
Published: November 2023

Գ­լո­բալ հա­կադ­րութ­յան ներ­կա փու­լը Արև­մուտ­քի ու ՌԴ-ի միջև ան­նա­խա­դեպ է թե՛ իր ծա­վա­լով­, թե՛ իր խո­րութ­յամբ, թե՛ առ­ճա­կատ­ման բնույ­թով: Ն­ման հա­կադ­րութ­յու­նը պայ­ման­ներ է ստեղ­ծում, որ նոր դեր ու նշա­նա­կութ­յուն ստա­նան մի­ջազ­գա­յին անվ­տան­գութ­յան ա­պա­հով­ման մե­խա­նիզմ­նե­րը, կազ­մա­կեր­պութ­յուն­նե­րը և մի­ջազ­գա­յին ի­րա­վուն­քը: Հա­կադ­րութ­յան ներ­քո փո­փոխ­վում է ԽՍՀՄ փլու­զու­մից հե­տո ձևա­վոր­ված աշ­խար­հա­կար­գը և գ­լո­բալ ու­ժա­յին հա­վա­սա­րակշ­ռութ­յու­նը:
Հվ. Կով­կա­սում ու­ժա­յին հա­վա­սա­րակշ­ռութ­յու­նը փոխ­վեց 2020 թ. պա­տե­րազ­մի արդ­յուն­քում: Ն­շենք, որ մինչ օրս մեր տա­րա­ծաշր­ջանում ու­ժա­յին որ­ևէ բա­լանս դեռևս չի ձ­ևա­վոր­վել: Դ­րա մա­սին են վկա­յում ՀՀ-ի և Ար­ցա­խի շուր­ջը շա­րու­նակ­վող լար­վա­ծութ­յու­նը, տե­ղա­յին ռազ­մա­կան սադ­րան­քե­րը: Հոդ­վա­ծում վեր­ոնշ­յալ ի­րո­ղութ­յուն­նե­րի հա­մա­տեքս­տում քննարկ­վում են ՀՀ ազ­գա­յին շա­հե­րի հստա­կեց­ման հար­ցադ­րում­նե­րը, ներ­կա­յաց­վում է, թե ինչ գոր­ծոն­ներ են դրանց վրա ազ­դում ներ­կա պայ­ման­նե­րում, կար­ևոր­վում է ազ­գա­յին շա­հե­րը ձևա­կեր­պե­լու գոր­ծըն­թա­ցում ռե­սուր­սա­պա­հով­վա­ծութ­յան դե­րը: Սույն ու­սում­նա­սի­րութ­յան մեջ ՀՀ ազ­գա­յին շա­հե­րի ձևա­կերպ­ման հար­ցում կար­ևոր դեր է տրվում անվ­տան­գա­յին ռիս­կե­րի և ռազ­մա­կան պա­րա­դիգ­մի ընտ­րութ­յա­նը, ո­րոնք պետք է ար­տա­ցո­լեն տա­րա­ծաշր­ջա­նում դեռևս չձա­վոր­ված ու­ժա­յին հավ­ասա­րակշ­ռութ­յու­նը: Հոդ­վա­ծում կար­ծիք է հայտն­վում, որ ՀՀ անվ­տան­գութ­յան ա­պա­հով­ման գոր­ծըն­թա­ցում պետք է ի­րա­տե­սա­կան ու սթափ գնա­հատ­վեն ՌԴ-ի հետ դաշ­նակ­ցա­յին հա­րա­բե­րութ­յուն­նե­րը:
Պետական կառավարման համակարգի թվայնացման հիմնահարցերը ՀՀ-ում
Authors: Խաչատրյան Կառլեն
Published: November 2023

Ժա­մա­նա­կա­կից աշ­խար­հում թվա­յին փո­խա­կեր­պում­նե­րը դար­ձել են մարդ­կա­յին կեն­սա­գոր­ծու­նեութ­յան ան­քակ­տե­լի բա­ղադ­րի­չը։ Դ­րանք վե­րա­բե­րում են այն փո­փո­խութ­յուն­նե­րին, ո­րոնք կա­րող են ա­ռա­ջա­նալ բիզ­նես մո­դել­նե­րում, կազ­մա­կերպ­չա­կան տա­րա­տե­սակ կա­ռուց­վածք­նե­րում և­ այլ գոր­ծըն­թաց­նե­րում։ Պե­տա­կան կա­ռա­վար­ման հա­մա­կար­գում թվայ­նա­ցու­մը գնա­լով ա­վե­լի մեծ թափ է հա­վա­քում։ Հոդ­վա­ծում ներ­կա­յաց­վում են պե­տա­կան կա­ռա­վար­ման հա­մա­կար­գում թվա­յին փո­խա­կեր­պում­նե­րի հիմ­նա­կան ա­ռանձ­նա­հատ­կութ­յուն­նե­րը, բա­ղադ­րիչ­նե­րը, քա­ղա­քա­ցի­նե­րի և բիզ­նե­սի հետ պե­տութ­յան փո­խառն­չութ­յուն­նե­րի հիմ­նա­կան թվա­յին մո­դել­նե­րը։ Քն­նարկ­վել են ՀՀ պե­տա­կան հա­մա­կար­գում թվա­յին փո­խա­կեր­պում­նե­րի է­վոլ­յու­ցիան, զար­գաց­ման ա­ռանձ­նա­հատ­կութ­յուն­նե­րը, հիմ­նա­կան թվա­յին հար­թակ­ներն ու դրանց ըն­ձե­ռած հնա­րա­վո­րութ­յուն­նե­րը։ Ա­ռանձ­նա­կի ու­շադ­րութ­յուն է նվիր­վել թվայ­նաց­ման գոր­ծըն­թա­ցի ռազ­մա­վա­րա­կան կա­ռա­վար­մա­նը, հա­յե­ցա­կար­գա­յին մո­տե­ցում­նե­րին։ Վեր­լուծ­վել է ՀՀ դիր­քը Մ­տա­վոր սե­փա­կա­նութ­յան հա­մաշ­խար­հա­յին կազ­մա­կեր­պութ­յան Գ­լո­բալ նո­րա­րա­րութ­յան հա­մաթ­վի, դրա են­թա­բա­ղադ­րիչ­նե­րի, ինչ­պես նաև ՄԱԿ-ի Է­լեկտ­րո­նա­յին կա­ռա­վար­ման զար­գաց­ման հա­մաթ­վի և դ­րա են­թա­բա­ղադ­րիչ­նե­րի հա­մա­տեքս­տում։ Վեր են հան­վել թվայ­նաց­ման ո­լոր­տում ՀՀ գլխա­վոր հիմ­նախն­դիր­նե­րը։ Մաս­նա­վո­րա­պես քննարկ­վել են թվա­յին գրա­գի­տութ­յան, թվա­յին հար­թակ­նե­րի վե­րա­բեր­յալ հա­սա­րա­կութ­յան ի­րա­զեկ­վա­ծութ­յան ցածր մա­կար­դա­կի, թվա­յին գոր­ծիք­նե­րի նկատ­մամբ հա­սա­րա­կութ­յան վստա­հութ­յան աս­տի­ճա­նի, կի­բե­րանվ­տան­գութ­յա­նը վե­րա­բե­րող խնդիր­նե­րը, ընդգծ­վել է պե­տա­կան թվա­յին հար­թակ­նե­րի կա­ռուց­ման միաս­նա­կան սկզբունք­նե­րի և չա­փա­նիշ­նե­րի, ինչ­պես նաև պե­տա­կան թվա­յին հար­թակ­նե­րի միջև կա­պե­րի բա­ցա­կա­յութ­յու­նը։
The Meaning of Badung Traditional Market Traders Accounting Practices in Tri Hita Karana Cultural Value
Authors:   Accounting Study Program, Faculty of Economic and Business, Warmadewa University, Eka Pertiwi I Dewa Ayu , Ayu Kristiantari I Dewa ,   Accounting Study Program, Faculty of Economic and Business, Warmadewa University, Sutapa I Nyoman ,   Accounting Study Program, Faculty of Economic and Business, Warmadewa University
Published: November 2023

Purpose — this study aims to explore and understand the meaning behind how to practice accounting, which is internalized in the daily lives of traders in the Badung-Bali Traditional Market through the cultural values of Tri Hita Karana. Design/methodology/approach — the researcher used a qualitative-interpretive paradigm with an ethnomethodological approach to achieve the research objectives. Data collection uses three methods, namely in-depth interviews, participant observation, and documentation. Data analysis used Garfinkel's (1967) analysis phase, namely indexicality analysis, reflexivity analysis, and action-contextual analysis, as well as the process of presenting common sense knowledge of social structure. Findings — the results of this study indicate that there are simple posts made in the imagination of traditional market traders according to the needs that are considered essential to them. In addition to the necessities of life, traditional market traders are aware of debts that must be paid due to purchasing their merchandise from suppliers. Practical implications — The use of Tri Hita Karana culture not only creates the meaning of accounting practice as an activity loaded with holistic tolerance, care, and interconnection among traditional market participants, but also the spiritual value inherent in the daily trading activities of traditional market traders Originality/value — the accounting practices carried out by traditional market traders do not only generate profits (money-material) but also non-material benefits, which emphasize the values of harmony and interconnection of traders with their surroundings, both in the relationship between traders and buyers. (seen in the practice of “nulungin” or helping each other and “ngemaang karting” or discount), the relationship between traders and the environment in which they work (because a clean environment is the "payuk jakan" i.e., main source of income of the traders), and the relationship between traders and the existence of God, which is seen as not a separate thing in their daily livelihood (see from mebanten or praying and offerings activities).