bluuebunny/crossref_metadata_2025 huggingface dataset:
Кризис маскулинности в романе Kонстантина Вагинова Гарпагониана
Authors: Чечнёв Яков
Published: November 2021

The article examines the image of Lokonov, a character in Konstantin Vaginov's novel Garpagoniana. The author proves that masculinity is inextricably linked to the character's desire to regain his youth, which is understood as subjectivity. Having been turned by the regime into a thing, a butterfly impaled on a pin, Lokonov struggles to regain the ability to think and feel independently, without the tutelage of the state machine. However, all his attempts are unsuccessful due to the "mechanistic" consciousness of the hero.
Peter Karvaš v kontexte existencializmu
Authors: Panáčková Lucia
Published: November 2021

The article reflects dramatic work of Peter Karvaš in the context of existentialist philosophy. It points to the connection between the social situation and the author´s topic choice, emotional engagement and approach to characters. In the article the author defines the basic features of existentialist philosophy in the work of Peter Karvaš providing analysis of selected extracts. In particular the article deals with the issue of how male characters react to the same situation and their motives behind the reaction. The article also reveals subjective view of Karvaš on social events and their impact on people and Karvaš himself.
Problém „mužského“ jazyka (na príklade básní Migleny Nikolčinej a Ireny Ivanovej)
Authors: Dimova Irena
Published: November 2021

The paper is devoted to the problem of the „male“ language which can be found in the works of two Bulgarian poets – Miglena Nikolchina and Irena Ivanova (better known by her pseudonym Rene Karabaš). The author associates them with the change that happens in literary criticism and the literary production itself after the 1990s. The author considers the synthesis of poetry and prose, poetry and theory as an intertextual „dialogue” through which is possible to analyze the texts of both poets. Thematically, the article focuses on the ways in which the woman gains „a right to have a voice“ rejecting her gender to take up the poet’s word and on how man appears to be a „quotation” in their works.
Migrácia v umeleckej literatúre Bariaková Zuzana, Jakubík Henrich, Kubealaková Martina: Hranice okolo nás a v nás: Literárne podoby migrácie v slovenskej literatúre, 2019
Authors: Tatár Jozef
Published: November 2021

x
Anuario
Authors: . Anuario
Published: November 2021

.
Historia oral y contemporaneidad
Authors: Thompson Paul
Published: November 2021

¿Cuál debería ser nuestra visión acerca de las potencialidades futurasde la historial oral en el umbral del Nuevo siglo? Hacerse tal preguntainmediatamente dispara una segunda: ¿qué entendemos por “historiaoral”? Para ofrecer algunas respuestas amplias a este desafío quisierarecurrir a mi propia experiencia de 30 años de trabajo en el campo de lahistoria oral.
El general Balza y la construcción de una memoria alternativa del Ejército argentino
Authors: Mazzei Daniel
Published: November 2021

La noche del 25 de abril de 1995, el teniente general Martín Balzaleyó, en el programa Tiempo Nuevo, un discurso (conocido como “autocrítica”) que marcó el inicio de una revisión de la memoria histórica del Ejército argentino. No fue sino el primer paso hacia la construcción de una nueva memoria institucional que pretende ser alternativa a la lectura del pasado reciente impuesta por los generales procesistas.La investigación parte de la hipótesis que la “autocrítica” no fue sólo la respuesta a una coyuntura política particular sino que Balza se proponía construir una nueva tradición histórica al tiempo que desligaba al Ejército (como institución) de los crímenes contra la Humanidad cometidos por sus integrantes. Se trataba de recuperar la imagen institucional frente a la sociedad civil y “exorcizar los fantasmas de la dictadura”. A partir de entonces conviven, al interior del Ejército, dos memorias rivales, cada una de las cuales incorporaba sus propios olvidos, en un enfrentamiento “memoria contra memoria”. Para este estudio de la evolución del discurso de Balza han sido seleccionados tres textos claves: la ya citada “autocrítica” de 1995, un discurso de febrero de 1998 y, finalmente la autobiografía escrita en 2001, en la cual la memoria institucional alternativa alcanza su expresión definitiva. Al analizar estos tres textos el artículo propone,entre otras cosas, seguir la evolución del concepto de responsabilidad, reconstruir la relectura de la historia contemporánea del Ejército, los cuestionamientos a las leyes de Obediencia de Vida y Punto Final, y la forma en la que esta operación de memoria utiliza el Nunca más para atacar la teoría “de los dos demonios”.Llegados a este punto debemos preguntarnos si esa versión definitiva que construye Balza, es aceptada más allá de su círculo íntimo, o es tan solo un gesto personal de un jefe con ambiciones políticas. O más aún, ¿estamos ante una nueva conciencia militar? ¿Hasta dónde el Ejército participa de política institucional? ¿Los valores de respeto a la vida y a la democracia, y el relato del pasado reciente que Balza pregonaba como propios son asumidos, compartidos y aceptados por todo el Ejército? Quizás podamos resumir todas estas preguntas en una sola: ¿ha tenido éxito Balza en esta operación por imponer una memoria alternativa institucional al Ejército argentino?
El progreso como ensoñación social. Espacialidades de la modernidad en Rosario, Argentina.
Authors: VERA Paula
Published: November 2021

En este artículo se trabaja sobre las significaciones sociales que incidieron en la construcción de las espacialidades en la ciudad de Rosario desde 1852 hasta los primeros años del siglo XX, haciendo especial hincapié en la idea de progreso como deseo y sueño colectivo que opera con fuerza simbólica en las materialidades de la ciudad moderna. Esto se observa en los discursos oficiales de los archivos del Concejo Deliberante y otras publicaciones municipales, los discursos periodísticos de la época y cierto discurso historiográfico que contribuyó a formalizar un relato de Rosario como hija de su propio esfuerzo. Se analiza la apropiación y la resignificación de lo que significó ser modernos en el caso de Rosario indagando puntualmente los sentidos que fueron adquiriendo determinados espacios públicos en sus procesos de construcción, la nominación de las calles y los proyectos urbanísticos que imitaban a París como ciudad modelo de la Modernidad. Palabras clave: progreso- imaginarios sociales- espacialidad-Rosario.
DIANA, Marta. Buscando el Reino. La opción por los pobres de los argentinos que siguieron al Concilio Vaticano II; Planeta; Buenos Aires; 2013; [515 páginas].
Authors: Fernández Leonardo
Published: November 2021

DIANA, Marta. Buscando el Reino. La opción por los pobres de los argentinos que siguieron al Concilio Vaticano II; Planeta; Buenos Aires; 2013; [515 páginas].
Relaciones fronterizas entre el Estado nacional argentino y líderes cacicales de Nordpatagonia 1870-1880
Authors: Stefanelli Sofía
Published: November 2021

El presente artículo intenta analizar las relaciones que se establecieron entre el Estado Nacional argentino y algunos líderes cacicales de Nordpatagonia alrededor de 1870 hasta 1880. El objetivo es comparar dos casos diferentes que se encuentran en el mismo escenario de acción: el avance militar del Ejército argentino sobre la frontera indígena. Se intenta mostrar el aporte de los cronistas de época al proceso de formación estatal y reflejar la dinámica de la política de parlamentos en el período previo a las campañas militares. Éstas impusieron un quiebre notable en las relaciones de frontera, en un momento en el que era necesaria la incorporación sucesiva de las tierras al modelo agroexportador en crecimiento y el proyecto de “homogenización cultural” de época.En este sentido, Valentín Sayhueque y Feliciano Purrán mantuvieron relaciones con el gobierno de Buenos Aires muy diferentes, lo que definió su accionar frente al avance estatal en 1879 y el desenlace de las campañas militares. La modalidad de cada cacique demuestra la complejidad de los grupos étnicos y una política que no era uniforme en las sociedades indígenas, a pesar de las visiones homogéneas tradicionales. Los pactos y parlamentos celebrados entre nativos y el gobierno nacional dieron cuenta de estas relaciones complejas y diversas que manifestaron la relevancia del mundo fronterizo.Palabras Claves: Estado Nacional; Frontera; Avance militar; Valentín Sayhueque; Feliciano Purrán
Masa, calidad, direccionalidad. ¿Cuál es la verdadera diferencia entre ‘osteopenias’ y ‘osteoporosis’?
Authors: Ferretti José Luis , Nocciolino Laura María , Lüscher Sergio Hugo , Mackler Leandro , Beribé Raúl Sergio , González Romina , Pilot Nicolás , Pisani Leandro , Cointry Gustavo Roberto , Capozza Ricardo Francisco
Published: November 2021

La OMS distingue osteopenias (simples pérdidas de masa ósea mineralizada) de osteoporosis (pérdidas con tendencia a la fractura) según la simple magnitud densitométrica del déficit mineral. En realidad, la resistencia de un hueso no depende de su masa mineralizada, sino de la combinación de la rigidez (resistencia a deformarse) y la tenacidad (resistencia a resquebrajarse) de su estructura, determinadas, a su vez, por la ‘calidad mecánica’ (rigidez y tenacidad) del tejido mineralizado y la ‘calidad arquitectónica’ de su distribución en cortezas y tramas trabeculares (diseño óseo). La resistencia ósea responde a un mecanismo retroalimentado (‘mecanostato’), que adecua la distribución del tejido a su calidad, en función del sensado de las mini—deformaciones derivadas del uso, a cargo de los osteocitos. Ergo, la resistencia ósea no es una cuestión de masa, sino de ‘estructura’ y ‘organización’ servo—controladas. Entonces, la diferencia entre osteopenias y osteoporosis, independientemente de la masa densitométrica, debe interpretarse evaluando el impacto estructural de la variable interacción de dos determinantes independientes: 1. el entorno mecánico direccional del esqueleto (input del mecanostato), y 2. su entorno sistémico humoral, no direccional, cuyas alteraciones perturban el control biomecánico direccional ‘1’. El componente ‘1’ (desuso) debe tratarse fisiátricamente, mediante estímulos mecánicos específicamente direccionados. El componente ‘2’ (metabólico) requiere drogas específicas, cuyos efectos sistémicos sobre osteocitos, osteoblastos formadores y osteoclastos destructores de hueso están fuertemente condicionados a la normalidad de (1). El éxito terapéutico dependerá de en qué medida se reconsidere a las osteoporosis, no como enfermedades de la masa, sino del diseño óseo.
Fast ice dynamics of the sea of Azov in the XXI centure
Authors: Magaeva Anastasiia , Yaitskaya Natalia
Published: November 2021

The article is dedicated to the investigation of the fast ice dynamics for the period 2000–2020 according to satellite data and field observations using GIS technologies. We used data from International Data Center – Sea Ice and coastal observation points to analyze long-term changes. Data processing and analysis was carried out using the ArcGIS 10.4 software package.

As a result, data were obtained on the spatial and temporal variability of fast ice in the Sea of Azov for the 2000–2020. The area and width of fast ice, the periods of formation, destruction and duration were analyzed. The maps of the fast ice formation frequency were constructed for each month of the winter period: December–March. It is shown that the duration of fast ice on all coastal observation points decreased: for points on the northern coast Taganrog and Mariupol—by 3–5 days, for points on the southern coast of Taganrog Bay—Yeisk and Dolzhanskaya—by 10–12 days, for point Genichesk—7 days. Average long-term fast ice area for 2000–2020 is 1800 km2. But against the background of an increase in winter air temperatures, the fast ice area is decreasing, and in the last winter periods it is not observed. The width of the fast ice at the northern coast of the Sea of Azov and the Taganrog Bay is 5–10 km. In the western and southeastern parts of the sea (sections Temryuk, Arabatskaya and Obitochny), the fast ice width is 2–5 km on average over the winter and was observed in 25 % of cases.
George Floyd’s Murder
Authors: Raees Kazemi Farnaz , Akefi Ghaziani Moosa
Published: November 2021

George Floyd’s murder by the police in Minneapolis provoked widespread political agitation across the country. It once again highlighted the problematic racial dimension of policing and eggregious violation of human rights commitments on the part of the government. In this article we explore how the human rights law and racism in the United States interact with each other? We employ qualitative research based on descriptive-analytical method and divide the article in four parts: a brief introduction, a historical background of racism, a conceptual comprehension of racial discrimination and a brief survey of the international human rights instruments against racism, and the onground situation of racial discrimination in the country. We conclude that the process of negotiation between human rights law and racism in the United States is far from settled yet.
Stochastic Optimization of Microgrid Operation With Renewable Generation and Energy Storages
Authors: Aaslid Per , Korpås Magnus , Belsnes Michael M , Fosso Olav Bjarte
Published: November 2021

The operation of energy storage systems (ESSs) in power systems where variable renewable energy sources (VRESs) and ESSs must contribute to securing the supply, can be considered as an arbitrage against scarcity. The value of using stored energy instantly must be balanced against its potential future value and future risk of scarcity. This paper proposes a multi-stage stochastic programming model for the operation of microgrids with VRESs, ESSs and thermal generators that is divided into a short- and a long-term model. The short-term model utilizes information from forecasts updated every six hours, while the long-term model considers the value of stored energy beyond the forecast horizon. The model is solved using stochastic dual dynamic programming and Markov chains, and the results show that the significance of accounting for short- and long-term uncertainty increases for systems with a high degree of variable renewable generation and ESSs and limited dispatchable generation capacity.
ДОСЛІДЖЕННЯ ПОКАЗНИКІВ ЯКОСТІ ЗАМОРОЖЕНОГО НАПІВФАБРИКАТУ ДЛЯ СМУЗІ
Authors: Соколова Є. Б.
Published: November 2021

У статті досліджено споживні властивості напівфабрикату для виробництва напою смузі та його показники якості впродовж 270 діб зберігання за температури –18±2 °C. Запропоно- вано рецептуру напівфабрикату для смузі, який включає в себе айву, полуницю, сік шипшини та вівсяні пластівці. Ця рецептура забезпечує оптимальну збалансованість основних нутрієнтів з одночасним збереженням високих смакових властивостей готового продукту. Протягом усього терміну низько- температурного зберігання систематично досліджували органолептичні та фізико-хімічні показ- ники. Результати органолептичної оцінки напівфабрикату показали, що продукт характеризується високою якістю. Консистенція напівфабрикату як до заморожування, так і після була однорідною, з рівномірно розподіленою м’якоттю. Колір після заморожування залишився яскравим, рівномірний по всій масі. Смак і запах яскраво виражені, приємні і гармонійні. Виявлено, що під час низькотемпера- турного зберігання в напівфабрикаті для смузі відбулися незначні зміни фізико-хімічних показників. Установлено, що масова частка сухих розчинних речовин упродовж дев’яти місяців зменшилася від 23,51% до 21,34%, вміст цукрів також зменшився на 0,58%. Під час зберігання замороженого напів- фабрикату титрована кислотність збільшилася на 0,60%, а вітамін С зменшився від 38,58 мг / 100 г до 34,18 мг / 100 г. Проте ці зміни незначні, тому не спричиняють погіршення якості напівфабрикату. Наведено результати мікробіологічних досліджень, встановлено кількісну зміну мікрофлори у процесі низькотемпературного зберігання. Кількість МАФАнМ після 30, 90, 180 и 270 низькотемпературного зберігання за температури –18±2 °С значно зменшується порівняно зі свіжовиготовленим Кількість дріжджів та плісеневих грибів також зменшується в процесі зберігання. Важливим є дотримання санітарно-гігієнічних норм під час виготовлення, пакування, зберігання та реалізації, бо повного від- мирання мікрофлори не відбувається. Виготовлення даного напівфабрикату для смузі дасть змогу розширити асортимент замороженої продукції та збільшити базу місцевої переробної промисловості.
Influence of Rehabilitation measures on the state of static and motor functions in Children with Cerebral palsy
Authors: Strashko Yevhen Yu. , Zhamardiy Valeriy O. , Donchenko Viktoriia I. , Shkola Olena M. , Lyakhova Natalia A. , Saienko Volodymyr G. , Tolchieva Hanna V.
Published: November 2021

Aim: The article experimentally tests the influence of rehabilitation measures on the state of static and motor functions in children with cerebral palsy (CP). It was found that medical rehabilitation of children with cerebral palsy requires the development of adequate strategies and tactics, integrated approach, application, if possible, of non-drug methods (physiotherapy, kinesitherapy).
materials and methods: During the study, the effectiveness of a set of rehabilitation measures was evaluated in 168 children aged 3 to 7 years, with spastic forms of cerebral palsy. All children were divided into two observation groups: the main group, which conducted the proposed rehabilitation course (n = 98) and the control group, which underwent a course of generally accepted rehabilitation content (n = 70).
Results: As a result of experimental work, the increase in indicators in the experimental group was higher. And although in the blocks “lying on your back”, “sitting on the floor”, “sideways turns”, “lying on your stomach”, “on your knees” and “standing and getting up” the difference between the indicators of the groups was insignificant (P> 0.05), we observed the best tendency to recovery in children of the study group in the blocks “crawling”, “sitting”, “walking”. The average increase in testing scores using the scale for assessing large motor functions in the study group was much higher than in the control.
Conclusions: A comparative evaluation of the effectiveness of comprehensive rehabilitation of children with spastic forms of cerebral palsy, found that the use of the developed program allows to achieve a clear therapeutic effect to improve the results of rehabilitation.
Increase in motion Range of the Cervical spine by means of physical Rehabilitation in Children with Cerebral palsy According to the severity of muscle pain
Authors: Strashko Yevhen Yu. , Donchenko Viktoriia I. , Zhamardiy Valeriy O. , Shkola Olena M. , Zakharov Oleg Yu. , Saienko Volodymyr G. , Tolchieva Hanna V.
Published: November 2021

Aim: The article experimentally examines the effect of rehabilitation measures on increasing the volume of movements of the cervical spine, taking into account the severity of muscle pain in children with cerebral palsy.
materials and methods: The study involved 168 children with spastic forms of cerebral palsy, they were divided into two observation groups: the main group, which conducted the proposed rehabilitation course (n = 98) and control, who underwent a course of conventional rehabilitation content (n = 70).
Results: During application of the proposed method, the therapeutic effect on pathologically significant areas of bilateral muscle kinematic chains was carried out taking into account their mutual antagonism, bilateral symmetry, taking into account the course of homolateral and heterolateral muscle spirals. Positive dynamics in the clinical status in the vast majority of patients during re-observation was achieved, but the effectiveness of rehabilitation and the stability of the achieved therapeutic effect in the study groups were different. Thus, in patients of the main and control groups, changes in the mobility of the cervical spine were detected, which were recorded using the proposed integrated assessment. Namely, in patients who were engaged in the proposed method, the amount of movement in the cervical spine (passive lateral tilt with an element of rotation) probably increased when compared with the indicators before rehabilitation. Also noteworthy is statistically significant reduction in pain intensity, which allows for more manipulative rehabilitation.
Conclusions: The proposed method of rehabilitation of children with spastic forms of cerebral palsy has a pronounced sanogenetic effect, meaning it stimulates their own health reserves and triggers a cascade of reactions of the body aimed at forming a healthy motor stereotype. It involves influence on organism of the patient by rehabilitation procedures with inclusion in work of all biokinematic muscular chain at the same time, taking into account spiral construction of muscles of a body, which allows to achieve a more pronounced therapeutic effect.
Masticatory muscle Activity in Individuals with Temporomandibular Disorder
Authors: Smaglyuk Lyubov V. , Liakhovska Anastasiia V.
Published: November 2021

Aim: The aim of our study was to investigate features related to EMG-activity of masticatory muscles in subjects with TMD.
materials and methods: The study comprised 22 patients with clinical symptoms of TMD. The average age of the subjects was 29.3 ± 4.4 years. Malocclusion was evaluated according to Angle classification, TMD – according to the Research Diagnostic Criteria (RDC/TMD). Registration of EMG-activity of masseter and anterior temporalis muscles was performed during maximum voluntary clenching, clenching on the right and left sides.
Results: Normal activity of the masticatory muscles is characterized by symmetrical and EMG-activity of the masticatory muscles on the left and right sides. EMG-activity of masticatory muscles in subjects with TMD are characterized by: 1) increased values of EMG-activity of temporal and masseter muscles; 2) disproportional and asymmetric muscle work of the masticatory muscles on the right and left sides.
Conclusions: Features of masticatory muscles activity in individuals with Angle Class I malocclusion and TMD were found.
Fundamentals of Improvement of the physical Qualities of schoolchildren Via Outdoor games
Authors: Rybalko Lina M. , Onishchuk Larysa M. , Horoshko Victoriia I. , Synytsya Tetiana O. , Yopa Tetiana V. , Bashtovenko Oksana A. , Ostapov Andrian V.
Published: November 2021

Aim: The objective of the research is the elaboration and the scientific justification of the methodology of the development of physical qualities of junior school children via the method of action-oriented games.
materials and methods: The methodology of the research is based on the usage of the theoretical, pedagogical, medical and biological methods, the method of monitoring of the steps and chronometry. The research was attended by the students of the 3rd and 4th year at Poltava general education school No22 of 1-3 degrees.
Results: The particularity of the elaborated method of the development of physical qualities is the application of physical exercises and action-oriented games in the course of physical education. The results of the experiment showed that the students from the experimental group had a significantly better level of physical qualities in the course of verification and experience slight fatigue in the course of action-oriented games. 79% out of 100% of the students of the experimental group experienced no difficulties in the course of execution of physical engagement during action-oriented games.
Conclusions: According to the analysis and summarization of the information from literature sources, it was discovered that physical qualities are the show of the motional capabilities of a child. Active motional activity leads to faster, but more importantly – to more harmonic maturing of morphological and functional systems of a student.
Medical Rehabilitation Carried out by the social Insurance Institution as part of Disability to work prevention
Authors: Winciunas Piotr , Lachman Dariusz
Published: November 2021

The Social Insurance Institution (ZUS) has been implementing a medical rehabilitation program as part of disability prevention since 1996. The purpose of medical rehabilitation is to improve the health condition of the insured in terms of regaining or maintaining the ability to work. Medical rehabilitation is carried out in those diseases that most often cause inability to work, and thus generate the greatest costs for the social insurance system. Currently, ZUS is referring to medical rehabilitation in: diseases of the musculoskeletal system, cardiovascular diseases, respiratory system diseases, psychosomatic diseases, people after treatment of breast cancer, voice organ diseases, people who, during an accident, in particular an accident at work, suffered an injury to the musculoskeletal system , diseases of the central nervous system. Its role is limited to supplementing the therapeutic process with medical measures aimed at improving the body’s efficiency, enabling the insured person or pensioner to return to employment. Hence, the subjective scope of its activities covers the insured at risk of total or partial incapacity for work and who are promising to start gainful employment as a result of its completion. The concept of incapacity for work means that a person who has lost the ability to work completely or partially due to a violation of the body’s efficiency is incapable of work and does not expect to regain the ability to work after retraining. A person who has lost the ability to perform any work is completely incapable of work. A person partially incapable of work is a person who has largely lost the ability to work in accordance with the level of their qualifications.
Obesity During a pandemic as a public health problem
Authors: Holovanova Iryna I. , Kasynets Svitlana S. , Pluzhnikova Tetiana V. , Krasnova Oksana I. , Bilous Alevtyna M. , Bondarenko Valerii V. , Yatsenko Ihor V.
Published: November 2021

Aim: Identify the problem of obesity during a pandemic and ways to solve the problem in modern circumstances.
materials and methods: Materials of state statistics of Ukraine were used in the work. Sociological, epidemiological methods, as well as the method were used to solve problems.
Conclusions: According to research, people with a BMI of up to 30 die about nine years earlier than their slimmer peers. If the BMI is more than 45, life expectancy is reduced by an average of 13 years. Given that the average age of the population of Ukraine, according to official statistics, is 68 years, being overweight can take a sixth of a person’s life. Obesity increases the risk of various diseases, including diabetes, cancer and heart disease. Foreign experts say that the “obesity epidemic” is not so much due to incontinence and low activity, but to global changes in the way of life of mankind. However, while Ukrainian doctors are not very active in raising this issue. In our country, this problem has not become national, as, for example, in the United States. BMI is used to verify obesity. An indicator of the clinical risk of metabolic complications of obesity is also the size of the waist circumference. Expert opinions provided by the WHO and the National Institutes of Health suggest that with a low-calorie diet and increased physical activity, overweight people can lose no more than 10% of their initial weight. The approach to lifestyle change is a cornerstone for all people who are overweight and obese.
PERINATAL INFECTIONS IN UKRAINE: RESULTS OF A MULTICENTER STUDY
Authors: Salmanov Aidyn G. , Ishchak Oleg M. , Dobarin Serhii А. , Susidko Olena M. , Mosendz Olena V. , Korniyenko Svitlana M. , Voloshyn Oleksandr A.
Published: November 2021

The aim: To obtain the estimates of the сurrent incidence rate of perinatal infections, risk factors, as well as their associated impact on mortality and determine the antimicrobial resistance of responsible pathogens in Ukraine.
Materials and methods: We performed a multicentre retrospective cohort study was based on surveillance data. This study included infants aged 0 to 6 days delivered in 2017-2019 at 11 Ukrainian regional perinatal centers. Definitions of perinatal infections and mortality were used from the CDC/WHO/UNICEF.
Results: Of 18,348 liveborn infants, 472 (2.6%) perinatal infections were detected. The incidence of perinatal infection was 25.7 per 1000 live births. The most frequently identified types of infections were: bloodstream infections, 35.6 %, lower respiratory tract infections, 21.4%, Meningitis, 18.2%, Conjunctivitis, 11.9%, skin and soft tissue infections, 6.6%, Dacryocystitis, 3.8%, and urinary tract infections, 2.5%. Early mortality rates from perinatai infections was 51.1%, with an incidence of 13.1 deaths/1000 live births. Potential risk factors the development of perinatal infections and mortality were low birth weight, prematurity, low gestasional age, mode of delivery (manual aid), premature rupture of membranes, preterm premature rupture of membranes, prolonged rupture of membranes, turbid and meconeal amniotic fluid, infection of the mother during labor. resuscitation during delivery, invasive procedure, asphyxia. Main causative agents of perinatal infections were Escherichia coli, Streptococcus agalactiae, Staphylococcus aureus, Klebsiella pneumoniae, CoNS, Enterobacter cloacae, Pseudomonas aeruginosa.
Conclusions: This study showing that the high incidence rate of perinatal bacterial infections, as well as their associated impact on mortality, and presents a significant burden to the Ukraine.
COMPARATIVE EVALUATION OF HISTOTOXICITY INDICATORS OF METAL ALLOYS FOR THE MANUFACTURE OF METAL CERAMIC DENTAL CONSTRUCTIONS
Authors: Hasiuk Petro A. , Ramus Мykhailo , Vorobets Anna , Tkachenko Iryna , Dzetsiukh Tetiana , Kalashnikov Dmytro , Rosolovska Svitlana
Published: November 2021

The aim: To carry out a comparative assessment of metal alloys for the manufacture of metal-ceramic constructions of dentures by determining the indicator of their histotoxicity.
Materials and methods: To identify the effect of metal alloys on cobalt and nickel bases on the tissue of organism, we carried out an experimental-morphological study of standard samples of metal alloys “Shot-alloy”, “Remanium-2000”, “Cerium”, “Dent-NCB”, “Cellite-N”.
Results: A careful histological analysis of the capsules formed around the metal alloy samples during two periods of the experiment showed that the healing time of the subcutaneous tissue was not the same. The most complete healing, that is, the formation of mature fibrous connective tissue, occurred during the implantation of the cobaltbased alloy “Remanium-2000” and the capsule formed at the end of the experiment around the implanted sample from the “Shot-alloy” alloy, and during the implantation of the “Cerium” alloy, healing the wound surface and the formation of a connective tissue capsule occurs fully than in previous cases.
Conclusions: The analysis of the performed experiment testifies in favor of the point of view that the speed and quality of healing of damaged subcutaneous tissue upon the introduction of implanted research alloys depend largely on the individual chemical components that make up the alloys, or on their combination.
CHARACTERISTICS OF CD68+ AND CD163+ EXPRESSION IN PLACENTA OF WOMEN WITH PREECLAMPSIA AND OBESITY
Authors: Zelinka-Khobzey Marta M. , Tarasenko Kostiantyn V. , Mamontova Tetiana V. , Shlykova Oksana A.
Published: November 2021

The aim: To study the peculiarities of CD68+ and CD163+ macrophage expression in the placentas of women with obesity who developed preeclampsia by applying immunohistochemical method.
Materials and methods: The study included 20 placentas taken from women who delivered full-term live-birth babies. The women were divided into 4 groups of 5 individuals each: women with physiological body weight (1st group); women with class II obesity (2nd group); women with physiological body weight and preeclampsia (3rd group); women with class II obesity, who developed preeclampsia (4th group).
Results: The analysis of the expression level of CD68+ and CD163+ decidual macrophages shows the predominance of CD68+ pro-inflammatory profile over CD163+ anti-inflammatory profile in women of all groups. Evaluation of CD68+ and CD163+ expression levels of Kashchenko-Hofbauer cells in the stroma of the terminal villi of the placenta shows that the expression level of CD68+ macrophages is significantly higher in women with obesity and preeclampsia than in the control, or in women with obesity or preeclampsia. There was a reverse tendency to the polarization shift in Kashchenko-Hoffbauer cells in the stroma of the terminal villi towards the predominance of CD163+ macrophages over CD68+ macrophages in all groups of women.
Conclusions: The imbalance in anti-inflammatory and pro-inflammatory profile of placental macrophages with a predominance of the latter can lead to the development of preeclampsia.
KEY ASPECTS OF ORGANIZATION OF THE PROCESS AND INDIVIDUAL CHARACTERISTICS OF NUTRITION OF PUPILS AND STUDENTS OF DIFFERENT TYPES OF MODERN EDUCATIONAL INSTITUTIONS
Authors: Tymoshchuk Oksana V. , Sotnikova-Meleshkina Zhanna V. , Melnyk-Sheremeta Olha P. , Zahorodnieva Oksana V. , Kryvonos Krystyna A. , Ostrovska Kseniia M.
Published: November 2021

The aim: Study the key aspects of organization of the process and individual characteristics of nutrition of pupils and students of different types of modern educational institutions.
Materials and methods: To adequately assess the process of organization of the regime and individual characteristics of nutrition of pupils and students of different types of modern educational institutions, we have evaluated the key characteristic features of a rational diet: number of daily meals and their duration, food consumption rate, conditions and priorities as well as distribution of dish volume and caloric content in accordance with food intake frequency.
Results: The results of the study have shown a significantly high rate of abuses in individual diet key components. Thus, majority of pupils and students do not observe proper food intake frequency, often skip their main meals, fail to maintain proper time intervals between meals, spent insufficient time for their main meals, incorrectly distribute food volume and caloric content according to the number of meals, do not have breakfast, consume the largest volume of food for their supper, eat their meals at a quick rate, and, certainly, abuse street and fast food.
Conclusions: The revealed violations of the basic nutrition principles and patterns may be the cause of functional disorders and adaptive incapabilities of the body, as well as the development of various polynutrient deficiencies and food-related diseases, therefore requiring justification and implementation of the possible ways of their correction.
PSYCHOLOGICAL FACTORS AND CONSEQUENCES OF PSYCHOSOCIAL STRESS DURING THE PANDEMIC
Authors: Maruta Natalya A. , Markova Marianna V. , Kozhyna Hanna M. , Aliieva Tetiana А. , Yuryeva Lyudmyla М. , Abdryakhimova Tsira B. , Pshuk Nataliia G. , Skrypnikov Andrii M.
Published: November 2021

The aim: Study of psychological factors and consequences of psychosocial stress which is formed during the COVID-19 pandemic.
Materials and methods: In the research, we used methods: developed a common, assessment of psychosocial stress L. Reeder scale, assessment of distress R.Kessler, assessment of the presence of manifestations of anxiety-depressive response GAD-7, depression self-assessment scale PHQ-9, method of assessing neuropsychological adaptation I. Gurvich, assessment of psychosocial support D. Ziemet, the scale of assessment of family anxiety E. Eidemiller, W. Justickis, strategies for stress-coping behavior E. Heim, methods of assessing the quality of life A.A. Pushkarev, N.G. Arinchina (2000). The current factors of the impact of coronavirus on the mental state of the population have been investigated. The study involved 823 citizens of Ukraine, who filled out the developed Google form.
Results: Threats of coronavirus disease, violation of the usual life stereotype, restriction of leisure activity, harmful interest in news about the pandemic, usage of tobacco plays an important role in the mechanisms of distress formation. These conditions raise the risk of increased stress, anxiety and depression.
Conclusions: The investigations carried out suggested that the quarantine restrictions could be predisposing factors for mental health impairments. Under these conditions, risks of increased stress pressure, anxiety, and depression are rising. Measures on psycho-prevention should be performed on the base of the regularities identified.
Optimization of Trans-esterification Process and Characterization of Biodiesel from Soapstock Using Silica Sulfuric Acid as a Heterogeneous Solid Acid Catalyst
Authors:   School of Chemical Engineering, Wollo University, Combolicha Campus, Dessie, Ethiopia, Latebo Samuel , Bekele Abreham ,   School of Chemical Engineering, Jimma Institute of Technology, Jimma University,Jimma, Ethiopia, Abeto Temesgen ,   School of Chemical Engineering, Jimma Institute of Technology, Jimma University,Jimma, Ethiopia, Kasule Job ,   Texas Tech University, Post-Doctoral research associate and Post Doctoral Fellow at West Virginia University, USA
Published: November 2021

The main objective of this study was production, optimization, and fuel quality characterization of biodiesel from equal weight ratio blended acid oil of cottonseed and sunflower soapstock using silica sulfuric acid as a solid acid catalyst in laboratory scale. The physicochemical properties of soap stock samples and extracted acid oil from each soap stock were determined. The experiment was designed by design expert (version 11) software. The 5-level 4-factors (methanol to acid oil molar ratio, catalyst weight, stirring rate, and reaction time) were designed using the central composite design method. From the experimental results, the maximum biodiesel yield of 90.68% was obtained using methanol to acid oil molar ratio of 7:1 using catalyst 5.5(%wt/wt) with a stirring rate of 300rpm at 3hr reaction time. The average value of triplicate experiment of biodiesel yield from the experimentation at optimized condition was 92.62%. The analysis of variance results indicated that satisfactory results were achieved. The carried out physiochemical properties of produced biodiesel were within a range and some were closest to American and European biodiesel standards.
Effect of Plant Growth Regulators and Explant Source on the Induction of Callus of Dianthus caryophyllus L.
Authors: Mahood Huda E.
Published: November 2021

In order to investigate the possibility for in in vitro fast regeneration of Dianthus caryophyllus, different concentrations of Kinetin (Kin), 2,4-Dichlorophenoxy Acetic Acid (2,4-D) had been tested for induction of callus by leaves and stems explant using Murashige and Skoog (MS) medium. After two months in culture, response callus in the induction rate, fresh and dry weight, texture and color were evaluated.  MS medium that contained 4.5 mg.L-1 2, 4-D was suitable for callus induction with leaf explants. The combination of 0.4 mg.L-1 Kin and 2.0 mg.L-1 2, 4-D also demonstrated a wonderful induction of callus on stem explants. In addition to the culture medium complemented by Kin and 2, 4-D, the influence of Zeatin at various concentrations (0.0, 0.4, 0.8 or 1.0 mg.L-1) was assessed.  In MS medium that  contained  0.4 mg.L-1 Kin+ 2.0 mg.L-1 2,4-D+ 1.0 mg.L-1 Zeatin, rapid callus induction and also more callus proliferation from stem explants were detected. Results indicate on callus induction that, Zeatin was more successful than Kin or 2, 4-D, but other combinations directly developed a shoot. Callus obtained from stems explant was friable, white and yellow, while callus from leaf explants was green.
SKRINING FITOKIMIA DAN UJI DAYA HAMBAT EKTRAK DAUN JAHE MERAH (Zingiber officinale var rubrum) TERHADAP BAKTERI Staphylococcus Epidermidis DAN Escherichia Coli
Authors: Ibrahim Annisa Humairah , Hasan Hamsidar , Sy. Pakaya Mahdalena
Published: November 2021

Infectious disease is one of the diseases caused by microbes, including bacteria. Staphylococcus epidermidis and Escherichia coli are gram-positive and gram-negative bacteria that cause infectious diseases. The selection of medicinal plants as an alternative solution is an effective way of reducing the resistance of bacteria. Based on the empirical data, herbal plants with antimicrobial potential are red ginger (Zingiber officinale var rubrum). This research aimed to determine the inhibition test on Staphylococcus Epidermidis and Escherichia coli due to phytochemical compounds contained in the leaves of red ginger which serve as an antibacterial. Through this experimental laboratory research, a crude drug was extracted using n-hexane, chloroform, ethyl acetate, and methanol solvent. The phytochemical screening results of n-hexane extract showed that red ginger leaves contain alkaloids and terpenoids; chloroform extract contains alkaloids, steroids, and tannins; ethyl acetate extract contains alkaloids, steroids, flavonoids, and tannins; and the methanol extract contains alkaloids, terpenoids, flavonoids, and tannins. Chloramphenicol and Dimethyl sulfoxide (DMSO) were used as the positive control and negative control respectively. Inhibition test results were obtained from the four n-hexane extracts, chloroform extracts, ethyl acetate extracts, and methanol extracts with three different concentrations.The results obtained the greatest inhibition against Staphylococcus Epidermidis bacteria, namely at a concentration of 20% chlorform extract of red ginger leaves as large as 18,90 mm. Meanwhile, the inhibition of Escherichia Coli is at a concentration of 20% n-hexane extract with an inhibitory power of 17,84 mm inhibition zone that is classified as a strong category to inhibit the growth of bacteria .The results of the One Way ANOVA data analysis (p less than 0.01) with a confidence level of 99%.
STANDARISASI DAN KADAR FLAVONOID TOTAL EKSTRAK ETIL ASETAT KULIT BATANG NANGKA (Artocapus heterophylus L)
Authors: Purnama Niluh Sri , Hasan Hamsidar , Pakaya Mahdalena Sy
Published: November 2021

Nangka (Artocarpus heterophylla L) adalah tumbuhan yang banyak terdapat di Indonesia. Hampir seluruh bagian pohon nangka dapat dimanfaatkan sebagai obat herbal dimana senyawa flavonoid terprenilasi merupakan metabolit sekunder utama yang terdapat dalam genus Artocarpus. Di Indonesia penggunaan obat herbal masih bersifat tidak terukur baik dari segi takaran, maupun proses penyiapannya. Sehingga perlu dilakukan standarisasi hal ini dilakukan untuk menjaga konsistensi serta keseragaman dari bahan obat herbal. Penelitian ini bertujuan untuk menentukan parameter standarisasi spesifik dan non spesifik serta menentukan kadar flavonoid total ekstrak etil asetat kulit batang nangka. Metode ekstraksi yang digunakan adalah maserasi bertingkat menggunakan pelarut n-heksan, etil asetat dan metanol. Hasil penelitian mengenai parameter organoleptik dari ekstrak etil asetat kulit batang nangka yaitu berwarna merah kehitaman, bau khas, rasa pahit sepat dengan tekstur kental. Simplisia kulit batang nangka memiliki tiga lapisan warna yaitu abu-abu kehijauan dengan bercak putih, lapisan orange dan lapisan coklat muda dengan permukaan tidak rata dan tebal kulit batang kurang lebih 1 cm, serbuk simplisia kulit batang nangka memiliki fragmen kristal oksalat bentuk prisma, serabut, jaringan gabus hablur, dan  parenkim dengan amilum. Ekstrak etil asetat mengandung senyawa flavonoid, dan alkaloid. Dan parameter non spesifik ekstrak etil asetat kulit batang nangka yaitu kadar air 16,97%, susut pengeringan 10,48%, kadar abu 9,78%, kadar abu tidak larut asam 1,58% dan bobot jenis 0,912. Dengan kadar flavonoid ekstrak etil asetat adalah 28,1025 µg/mL.
PENGARUH KONSENTRASI HYDROXYPROPYL METHYLCELLULOSE SEBAGAI BAHAN PENGIKAT PADA SEDIAAN TABLET EKSTRAK RIMPANG JAHE MERAH (zingiber officinale Var. Rubrum.)
Authors: Thomas Nur AIn , Susanti Abdulkadir Widy , Taupik Muhammad , Oktaviana Nur
Published: November 2021

Lozenges are solid preparations made from aromatic and sweet taste that can dissolve slowly in the mouth, which are intended to treat infections in the mouth and throat. Hydroxypropyl Methylcellulose (HPMC) is a binder that can be used in lozenges.This study attempted to examine the effect of the concentration of HPMC as a binder in the tablet preparation of red ginger rhizome extract (Zingiber officinale Var Rubrum) by wet granulation method. This study was a laboratory experimental study by comparing the three concentrations of HPMC binder used in each formula i.e., FI (4%), FII (5%), FIII (6%).The resulting tablets were tested for physical properties including organoleptic tests, weight uniformity, tablet hardness, tablet friability and hedonic tests. Based on the results of the study, it was shown that with an increase in the concentration of the HPMC binder, the physical quality of the resulting tablet also increased. The higher the concentration of HPMC used, the better the uniformity of weight and the high level of tablet hardness. However, tablet friability will decrease. The results showed that the concentrations of 4%, 5%, and 6% had an effect on the tablet physical properties whichwas fragility. Further, formula II with a concentration of 5% had better tablet physical quality and was preferred by respondentsbased on hedonic tests.
Good Laboratory Practice (GLP) in The European Union
Authors: Annisa Viviane
Published: November 2021

Regulasi GLP (Good Laboratory Practice) mengatur tentang cara bekerja pada laboratorium, pelatihan personel, standar operasional prosedur, software untuk pencatatan data, dokumentasi, dsb. Tujuan utama dari prinsip GLP adalah mengembangkan kualitas dari data pengujian sehingga tiap negara tersebut dapat menghasilkan data pengujian yang andal, menghindari pengujian berulang, serta menghemat waktu. Anggota OECD (Organization for Economic Co-operation and Development) sebanyak 29 negara di seluruh dunia, mencakup Asia-Pasifik, Amerika, serta Eropa. Patuh terhadap GLP dapat meniadakan barier perdagangan antar negara anggota. Prinsip GLP yang diaplikasikan di Uni Eropa sejalan dengan OECD, yakni untuk meningkatkan kualitas data pengujian yang valid. Anggota negara Uni Eropa adalah sebanyak 27 negara. Uni Eropa mengadopsi peraturan GLP pada tahun 1987. Amandemen terkait GLP dilakukan mengikuti OECD pada tahun 1999. Peraturan perundangan Uni Eropa tentang GLP ‘Directive 2004/9/EC’ kemudian menggantikan ‘Directive 88/320/EEC’ menjelaskan tentang tanggungjawab yang diberikan kepada anggota negara Uni Eropa untuk menetapkan otoritas inspeksi GLP pada masing-masing wilayah dan persyaratan Mutual Acceptance of Data (MAD). Pengujian non-klinik pada produk obat sesuai dengan ketentuan GLP mengacu pada OECD serta peraturan perundangan Uni Eropa yang terdiri dari ‘Directive 2004/10/EC’ dan ‘Directive 2004/9/EC’. Meskipun Inggris sudah keluar dari Uni Eropa, namun Mutual Acceptance of Data (MAD) tetap berlaku pada Inggris terhadap negara Eropa lainnya yang sama-sama anggota dari OECD. Otoritas terhadap inspeksi serta audit studi diserahkan pada negara masing-masing anggota.
Cosmologically Coupled Compact Objects: A Single-parameter Model for LIGO–Virgo Mass and Redshift Distributions
Authors: Croker Kevin S. , Zevin Michael , Farrah Duncan , Nishimura Kurtis A. , Tarlé Gregory
Published: November 2021

We demonstrate a single-parameter route for reproducing higher mass objects as observed in the LIGO–Virgo mass distribution, using only the isolated-binary stellar evolution channel. This single parameter encodes the cosmological mass growth of compact stellar remnants that exceed the Tolman–Oppenheimer–Volkoff limit. Cosmological mass growth appears in known solutions to General Relativity with cosmological boundary conditions. We consider the possibility of solutions with cosmological boundary conditions, which reduce to Kerr on timescales short compared to the Hubble time. We discuss complementary observational signatures of these solutions that can confirm or invalidate their astrophysical relevance.