bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Rare‐Earth Manganese Germanides RE2+xMnGe2+y (RE: La, Ce) Built from Four‐Membered Rings and Stellae quadrangulae of Mn‐Centred Tetrahedra.
Authors: Oliynyk Anton O. , Mar Arthur
Published: October 2013

La2+xMnGe2+y (I) and Ce2+xMnGe2+y (II) are prepared by arc‐melting of the elements in molar ratios of 2:1:2 followed by annealing (sealed silica tubes, 800 °C, 2 weeks).
ChemInform Abstract: Li3Ti4NiMnO12 and Li3Ti4NiCrO12: New Substituted Lithium Titanium Oxides.
Authors: El‐Shinawi Hany , Falk Mareike , Greaves Colin , Janek Juergen
Published: October 2013

The title compounds are synthesized by a sol—gel process from stoichiometric amounts of LiOAc, Ti(O‐iPr)4, Ni(OAc)2, Mn(OAc)2, and Cr(acac)3 dissolved in acetic acid and mixed with EDTA dissolved in NH3 solution.
ChemInform Abstract: Structural, Optical and Electric Properties of Nanocrystalline MgSe Thin Films Deposited by Chemical Route Using Triethanolamine as a Complexing Agent.
Authors: Ubale Ashok U. , Sakhare Y. S. , Ibrahim S. G. , Belkhedkar M. R.
Published: October 2013

MgSe thin films are deposited onto highly clean glass substrates from aqueous solutions of MgCl2, SeO2, N2H4·H2O, and triethanolamine at room temperature.
ChemInform Abstract: Enhanced Ferromagnetic Order in Sr4Mn3O3(GeO4)3 Featuring Canted [MnO4]∞ Spin Chains of Mixed‐Valent Mn(III)/Mn(IV). Aliovalent Substitution of the Sr4‐xLnxMnIII2+xMn IV1‐xO3(GeO4)3 Solid‐Solution.
Authors: West J. Palmer , Sulejmanovic Dino , Becht Gregory , He Jian , Hitchcock Dale , Yan Yonggao , Hwu Shiou‐Jyh
Published: October 2013

Crystals of Sr4‐xLnxMn3O3 (GeO4)3 (x = 0; x ≈ 0.15 for Ln: La, Pr, Nd, Sm, Eu, Gd, Dy; x ≈ 0.3 for Ln: Gd) are grown by solid state reactions of SrO, Ln2O3, MnO2 and Mn2O3, and GeO2 in a eutectic CsCl/SrCl2 flux (700 °C, 4 d).
ChemInform Abstract: Low Temperature Carbothermal and Boron Carbide Reduction Synthesis of LaB6.
Authors: Hasan Muhammad , Sugo Heber , Kisi Erich
Published: October 2013

Reasonably pure LaB6 can be synthesized at lower temperatures than previously reported.
ChemInform Abstract: Synthesis, Crystal Structure and Properties of [(dien)2Mn]Ge2S4 with Mixed‐Valent Ge Centers.
Authors: Yue Cheng‐Yang , Yuan Zhuang‐Dong , Zhang Lu‐Ge , Wang Ya‐Bai , Liu Guo‐Dong , Gong Liao‐Kuo , Lei Xiao‐Wu
Published: October 2013

The new title compound (dien: diethylenetriamine) is solvothermally synthesized from a mixture of Ge powder, Mn(OAc)2, and sulfur powder in aqueous dien solution (autoclave, 130 °C, 7 d, 7% yield).
ChemInform Abstract: Ruthenium‐Catalyzed Oxidation of Alcohols by Bromate in Water.
Authors: Hu Zongmin , Ma Li , Xie Jianhui , Du Hongxia , Lam William W. Y. , Lau Tai‐Chu
Published: October 2013

An efficient catalyst is applied to the oxidation of secondary‐ and primary alcohols to the corresponding ketones (II) or mixtures of aldehydes (IV) and carboxylic acids (V) with excellent conversions at room temperature.
ChemInform Abstract: Facile Synthesis of Ninhydrin and Isatin Based Hydrazones in Water Using PEG‐OSO3H as a Highly Efficient and Homogeneous Polymeric Acid‐Surfactant Combined Catalyst.
Authors: Debnath Kamalesh , Pathak Sudipta , Pramanik Animesh
Published: October 2013

Title compounds (III) and (V) are synthesized via reaction of ninhydrin (I) and isatin (IV) with the novel carbazate (II).
ChemInform Abstract: Construction of Enantiomerically Enriched Diazo Compounds Using Diazo Esters as Nucleophiles: Chiral Lewis Base Catalysis.
Authors: Mao Haibin , Lin Aijun , Shi Yan , Mao Zhijie , Zhu Xuebin , Li Weipeng , Hu Hongwen , Cheng Yixiang , Zhu Chengjian
Published: October 2013

Synthetic application of this method is demonstrated by several subsequent transformations, i.e.
ChemInform Abstract: Self‐Assembling Neodymium/Sodium Heterobimetallic Asymmetric Catalyst Confined in a Carbon Nanotube Network.
Authors: Ogawa Takanori , Kumagai Naoya , Shibasaki Masakatsu
Published: October 2013

A self‐assembled catalyst is shown to be efficient in anti‐selective asymmetric nitro‐aldol reactions.
ChemInform Abstract: A New and Efficient Method for the Synthesis of α,α‐Dihaloketones by Oxyhalogenation of Alkynes Using Oxone®—KX (X: Cl, Br, or I).
Authors: Madabhushi Sridhar , Jillella Raveendra , Mallu Kishore Kumar Reddy , Godala Kondal Reddy , Vangipuram Venkata Sairam
Published: October 2013

This is the first application of oxone as an oxidant for oxyhalogenation of alkynes.
ChemInform Abstract: Calcined Mg—Al Layered Double Hydroxide as a Heterogeneous Catalyst for the Synthesis of Urea Derivatives from Amines and CO2.
Authors: Zhang Ran , Hua Li , Guo Li , Song Baoning , Chen Jizhong , Hou Zhenshan
Published: October 2013

The title process gives the ureas in moderate yields and high selectivity (<99%).
ChemInform Abstract: Silver‐Catalyzed Trifluoromethylation of Arenes at Room Temperature.
Authors: Seo Sangwon , Taylor John B. , Greaney Michael F.
Published: October 2013

Application of this method is demonstrated by trifluoromethylation of the agrochemicals Napropamide (XV) and Pyriftalid (XVII).
ChemInform Abstract: Synthesis of Nitrodienes, Nitrostyrenes, and Nitrobiaryls Through Palladium‐Catalyzed Couplings of β‐Nitrovinyl and o‐Nitroaryls Thioethers.
Authors: Creech Gardner S. , Kwon Ohyun
Published: October 2013

Palladium‐catalyzed, copper‐activated desulfitative coupling reactions of thioethers with boronic acids allow the synthesis of a wide range of the title nitro compounds under mild conditions.
ChemInform Abstract: Chemoselective Hydroamination of Vinyl Arenes Catalyzed by an NHC‐Amidate‐Alkoxide Pd(II) Complex and p‐TsOH.
Authors: Giles Richard , O'Neill Justin , Lee Joo Ho , Chiu Michael K. , Jung Kyung Woon
Published: October 2013

Reaction of halide‐substituted and electron‐rich styrenes (I) with Ph—SO2—NH2 in the presence of a Pd(II)—NHC/TosOH catalyst system afford the cross‐coupled hydroamination products (III) in moderate to high yields in a Markovnikov‐type fashion.
ChemInform Abstract: CuBr2 Catalyzed Bromination/Oxidation of Isochromans to Benzaldehyde Derivatives.
Authors: Zhou Mei‐Yan , Kong Shan‐Shan , Zhang Ling‐Qiong , Zhao Ming , Duan Jin‐Ao , Zhen Ou‐yang , Wang Min
Published: October 2013

This new and efficient reaction is more suitable for isochromanes bearing no strong electron withdrawing or electron donating groups.
ChemInform Abstract: Dendrimers or Nanoparticles as Supports for the Design of Efficient and Recoverable Organocatalysts?
Authors: Keller Michel , Perrier Arnaud , Linhardt Roland , Travers Laurie , Wittmann Sebastian , Caminade Anne‐Marie , Majoral Jean‐Pierre , Reiser Oliver , Ouali Armelle
Published: October 2013

Dendrimers grafted with (S)‐α,α‐diphenylproline trimethylsilyl ether moieties are presented as organocatalysts.
ChemInform Abstract: Copper‐Mediated C—H Trifluoromethylation of Quinones.
Authors: Ilchenko Nadia O. , Janson Paer G. , Szabo Kalman J.
Published: October 2013

A copper(I)‐mediated trifluoromethylation of substituted quinones via C‐H activation and by using a hypervalent iodine reagents as trifluoromethylene‐source is reported.
ChemInform Abstract: Rhodium(I)‐Catalyzed Enantioselective Hydrogenation of Substituted Acrylic Acids with Sterically Similar β,β‐Diaryls.
Authors: Li Yang , Dong Kaiwu , Wang Zheng , Ding Kuiling
Published: October 2013

An efficient asymmetric Rh(I)‐catalyzed hydrogenation of β,β‐disubstituted acrylic acids is developed using a BINOL‐derived phosphine oxide as monodentate chiral ligand.
ChemInform Abstract: Desulfonylation of Tosyl Amides Through Catalytic Photoredox Cleavage of N—S Bond under Visible‐Light Irradiation.
Authors: Xuan Jun , Li Bin‐Jie , Feng Zhu‐Jia , Sun Guo‐Dong , Ma Huan‐Huan , Yuan Zhi‐Wei , Chen Jia‐Rong , Lu Liang‐Qiu , Xiao Wen‐Jing
Published: October 2013

This new desulfonylation is applicable to a wide range of tosyl amides bearing different sensitive functional groups.
ChemInform Abstract: Copper‐Catalyzed Oxidative Condensation of α‐Oxocarboxylic Acids with Formamides: Synthesis of α‐Ketoamides.
Authors: Wang Hua , Guo Li‐Na , Duan Xin‐Hua
Published: October 2013

Mechanistic studies show that the reaction proceeds via a radical process.
ChemInform Abstract: Diastereoselective Formation of 2,3,4,5‐Tetrasubstituted Tetrahydrofurans by a Lewis Acid Promoted Addition of C3‐Substituted 1,3‐Bis(silyl)propenes to Aldehydes.
Authors: Borg Tessie , Timmer Brian , Somfai Peter
Published: October 2013

The optimized reaction conditions result in the preferred formation of tetrahydrofurans (III) which are obtained as single diastereomers.
ChemInform Abstract: Gold‐Catalyzed Regioselective Synthesis of 2‐ and 3‐Alkynyl Furans.
Authors: Li Yifan , Brand Jonathan P. , Waser Jerome
Published: October 2013

Procedures are developed for the selective synthesis of 2‐ and 3‐alkynylated furans based on the use of hypervalent iodine reagents and gold catalysis.
ChemInform Abstract: Solvent‐Free Iridium(III)‐Catalyzed [2 + 2 + 2] Cycloaddition Providing Access to Fused Arenes: Isoindolines, Dihydroisobenzofurans and Indanes.
Authors: Auvinet Anne‐Laure , Michelet Veronique , Ratovelomanana‐Vidal Virginie
Published: October 2013

Carbon‐, nitrogen‐, and carbon‐tethered diynes undergo [2 + 2 + 2] cycloaddition reactions with alkynes to give the title species in moderate to good yields.
ChemInform Abstract: Efficient Synthesis of Cyclic Carbonates by MgII/Phosphine‐Catalyzed Coupling Reactions of Carbon Dioxide and Epoxides.
Authors: Ren Yiping , Shim Jae‐Jin
Published: October 2013

The catalytic system can be reused for at least six times without loss of catalytic activity.
ChemInform Abstract: Rhodium(III)‐Catalyzed Indazole Synthesis by C—H Bond Functionalization and Cyclative Capture.
Authors: Lian Yajing , Bergman Robert G. , Lavis Luke D. , Ellman Jonathan A.
Published: October 2013

Regioselectivity of the reaction is mainly controlled by the steric effects of the aromatic substituent at nitrogen [cf.
ChemInform Abstract: New Strategy for the Regioselective Synthesis of 1‐Phenyl‐3‐trifluoromethyl‐1H‐pyrazoles.
Authors: Zanatta Nilo , Amaral Simone S. , dos Santos Josiane M. , da Silva Andreia M. P. W. , Schneider Juliana M. F. M. , Fernandes Liana da S. , Bonacorso Helio G. , Martins Marcos A. P.
Published: October 2013

Title compounds (IV) are obtained in a two‐step procedure that involves the reaction of enones (I) with hydrazones (II), followed by deprotective hydrolysis and intramolecular nucleophilic heterocyclization.
ChemInform Abstract: Asymmetric Construction of Fluorinated Imidazolidines via Cu(I)‐Catalyzed exo‐Selective 1,3‐Dipolar Cycloaddition of Azomethine Ylides with Fluorinated Imines.
Authors: Li Qing‐Hua , Wei Liang , Chen Xuan , Wang Chun‐Jiang
Published: October 2013

An efficient method is elaborated for the asymmetric synthesis of fluorinated imidazolidines (III) and (IX) by a 1,3‐dipolar cycloaddition reaction.
ChemInform Abstract: Synthesis and Evaluation of an O‐Aminated Naphthol AS‐E as a Prodrug of CREB‐Mediated Gene Transcription Inhibition.
Authors: Xie Fuchun , Li Bingbing X. , Xiao Xiangshu
Published: October 2013

During the synthesis of O‐aminated naphthol AS‐E (IV), a novel reaction leading to oxazole (III) is discovered.
ChemInform Abstract: Novel Methods for the Synthesis of 4‐(Azol‐5‐yl)isoxazoles.
Authors: Bakulev V. A. , Efimov I. V. , Belyaev N. A. , Zhidovinov S. S. , Rozin Yu. A. , Volkova N. N. , Khabarova A. A. , El'tsov O. S.
Published: October 2013

Three title compounds of type (V) are prepared by the [3 + 2] cycloaddition reaction of enamines (III) and nitrile oxides generated in situ from hydroxamoyl chlorides.
ChemInform Abstract: Synthesis of New Series of 3‐Hydroxy/Acetoxy‐2‐phenyl‐4H‐chromen‐4‐ones and Their Biological Importance.
Authors: Gharpure Mangesh , Choudhary Ratiram , Ingle Vishwas , Juneja Harjeet
Published: October 2013

The title compounds (II), (III) are screened for their antimicrobial activity against S.
ChemInform Abstract: Synthesis of Ethyl 5‐Acetyl‐1‐R‐4‐aryl‐6‐hydroxy‐6‐methyl‐2‐oxopiperidine‐3‐carboxylates.
Authors: Sargsyan M. S. , Hayotsyan S. S. , Khachatryan A. Kh. , Badasyan A. E. , Panosyan G. A. , Kon'kova S. G.
Published: October 2013

5 Title compounds (III) are prepared from ethoxycarbonyl‐acetamides (I) and arylidene acetylacetones (II) by heterocyclization.
ChemInform Abstract: A New MCM‐41 Supported HPF6 Catalyst for the Library Synthesis of Highly Substituted 1,4‐Diyhdropyridines and Oxidation to Pyridines: Report of One‐Dimensional Packing Towards LMSOMs and Studies on Their Photophysical Properties.
Authors: Ray Suman , Brown Mike , Bhaumik Asim , Dutta Arghya , Mukhopadhyay Chhanda
Published: October 2013

A series of substituted 1,4‐dihydropyridines (IV) is readily prepared by a multi‐component condensation of diketones (I) with ketones (II), aryl aldehydes (III), and ammonium carbonate using MCM‐41 supported HPF6 as a novel heterogeneous catalyst.
ChemInform Abstract: Solvent‐Free Synthesis of Novel 5‐Oxo‐5H‐chromeno[4,3‐b]pyridine Derivatives.
Authors: Motamedi R.
Published: October 2013

14 Title compounds of type (III) are prepared using this new rapid, simple, and efficient solvent‐free synthetic procedure.
ChemInform Abstract: Synthesis and Antitumor Activity of Novel Coumarin Derivatives via a Three‐Component Reaction in Water.
Authors: Chen Zhiwei , Bi Jianhao , Su Weike
Published: October 2013

In a three‐component condensation catalyzed by the ionic liquid L‐2‐(hydroxymethyl)‐1‐(4‐sulfobutyl)pyrrolidinium hydrogen sulfate (HYSBPI) novel coumarin derivatives are obtained with excellent yields under microwave irradiation.
ChemInform Abstract: Synthesis and Antioxidant Activity of New Analogues of Quin‐C1.
Authors: Mierina I. , Tetere Z. , Zicane D. , Ravina I. , Turks M. , Jure M.
Published: October 2013

Newly synthesized tetrahydroquinazoline derivatives of type (III) show weak antioxidant activity.
ChemInform Abstract: Synthesis of 7‐Alkyl‐4‐amino‐7H‐pyrrolo[2,3‐d]pyrimidine‐6‐carboxylic Acids.
Authors: Verves E. V. , Kucher A. V. , Muzychka L. V. , Smolii O. B.
Published: October 2013

12 Title compounds of type (V) are prepared and screened for their potential biological activity.
ChemInform Abstract: A New Library of 4(3H)‐ and 4,4′(3H,3H′)‐Quinazolinones and 2‐(5‐Alkyl‐1,2,4‐oxadiazol‐3‐yl)quinazolin‐4(3H)‐one Obtained from Diaminoglyoxime.
Authors: Moghimi Abolghasem , Khanmiri Rahim Hosseinzadeh , Omrani Ismail , Shaabani Ahmad
Published: October 2013

Acetic acid mediated condensation of diarylaminoglyoxime (I) with anthranilic acids (II) or aminobenzoate (VI) leads to the formation of quinazolinones.
ChemInform Abstract: A Simple One‐Pot Synthesis of 2‐Substituted Quinazolin‐4(3H)‐ones from 2‐Nitrobenzamides by Using Sodium Dithionite.
Authors: Romero Angel H. , Salazar Jose , Lopez Simon E.
Published: October 2013

2‐Aminobenzamides, generated in situ from 2‐nitrobenzamides and Na2S2O4, react with aldehydes followed by cyclization and oxidation to furnish quinazoline derivatives.
ChemInform Abstract: Effective Synthesis of 3,5‐Diaryl‐(1H)‐pyrazin‐2‐ones via Microwave Mediated Ring Closure.
Authors: Johannes Eugen , Horbert Rebecca , Schlosser Joachim , Schmidt Dorian , Peifer Christian
Published: October 2013

Pyrazin‐2‐ones (II) (24 examples), present as scaffold in a number of biologically active compounds, are prepared via ring closure of diketoamides (I).
ChemInform Abstract: Borylation of Arenes with Bis(hexylene glycolato)diboron.
Authors: Liskey Carl W. , Hartwig John F.
Published: October 2013

The direct Ir‐catalyzed C‐H borylation of a variety of arenes with the commercially available title diboron reagent (II) is developed.
ChemInform Abstract: Hydrophosphinylation of Unactivated Alkenes with Secondary Phosphine Oxides under Visible‐Light Photocatalysis.
Authors: Yoo Woo‐Jin , Kobayashi Shu
Published: October 2013

Rhodamine B is applied as an inexpensive photocatalyst for the hydrophosphinylation reaction of alkenes (II) and (IV) with secondary phosphine oxides (I).
ChemInform Abstract: Direct Synthesis of β‐N‐Glycosides by the Reductive Glycosylation of Azides with Protected and Native Carbohydrate Donors.
Authors: Zheng Jianbin , Urkalan Kaveri Balan , Herzon Seth B.
Published: October 2013

A β:α‐selectivity <15:1 is observed in all reactions.
ChemInform Abstract: Whitmanoside A (I), a New α‐Pyrone Glycoside from the Leech Whitmania pigra
Authors: Li Tao , Wang Guo‐Cai , Huang Xiao‐Jun , Ye Wen‐Cai
Published: October 2013

isolation and structure elucidation
ChemInform Abstract: Solid State Electrochemical Hydrogen Sensor for Aluminum and Aluminum Alloy Melts
Authors: Schwandt Carsten
Published: October 2013

Review: 38 refs.
ChemInform Abstract: Large‐Scale, Plasma‐Assisted Growth of Nanowires
Authors: Cvelbar Uros , Sunkara Mahendra K.
Published: October 2013

Review: 116 refs.
ChemInform Abstract: Supramolecular Chemistry of Metal Complexes in Solution
Authors: Lanigan Nicholas , Wang Xiaosong
Published: October 2013

Review: 44 refs.
ChemInform Abstract: Gold(I)‐catalyzed Formation of Bridged and Fused Carbocycles
Authors: Barabe Francis , Levesque Patrick , Sow Boubacar , Bellavance Gabriel , Betournay Genevieve , Barriault Louis
Published: October 2013

Review: 52 refs.
ChemInform Abstract: Bioinspired Chemistry with Peptides — Asymmetric Catalysis, Molecular Scaffolds, Ag‐Nanoparticles
Authors: Wennemers Helma
Published: October 2013

Review: utility of peptides for the development of asymmetric catalysts, templates for the controlled formation of metal nanoparticles, and conformationally well‐defied molecular scaffolds.; 35 refs.
ChemInform Abstract: Natural Friedelanes
Authors: Shan Wei‐Guang , Zhang Li‐Wen , Xiang Jia‐Gui , Zhan Zha‐Jun
Published: October 2013

Review: occurrence and biological activities of all natural friedelane triterpenoids found between 1977 and March 2011; 344 refs.
ChemInform Abstract: Development and Applications of Highly Selective Palladium‐Catalyzed Monocoupling Reactions of (Cyclo)alkenes and 1,3‐Alkadienes Bearing Two or Three Electrophilic Sites and Bis(enol triflates) with Terminal Alkynes
Authors: Rossi Renzo , Bellina Fabio , Lessi Marco , Manzini Chiara
Published: October 2013

Review: < 250 refs.
ChemInform Abstract: Supported Gold Catalysts: New Properties Offered by Nanometer and Sub‐Nanometer Structures
Authors: Gates Bruce C.
Published: October 2013

Review: 21 refs.
ChemInform Abstract: Migratory Insertion of Alkenes into Metal—Oxygen and Metal—Nitrogen Bonds
Authors: Hanley Patrick S. , Hartwig John F.
Published: October 2013

Review: 111 refs.
ChemInform Abstract: Modular Columnar Supramolecular Polymers as Scaffolds for Biomedical Applications
Authors: Petkau‐Milroy Katja , Sonntag Michael H. , Brunsveld Luc
Published: October 2013

Review: 41 refs.
ChemInform Abstract: Polymer Mechanochemsitry: Techniques to Generate Molecular Force via Elongational Flows
Authors: May Preston A. , Moore Jeffrey S.
Published: October 2013

Review: 53 refs.
ChemInform Abstract: Polyoxometalates as Versatile Enzyme Inhibitors
Authors: Stephan Holger , Kubeil Manja , Emmerling Franziska , Mueller Christa E.
Published: October 2013

Review: 50 refs.
ChemInform Abstract: Process Engineering with Planetary Ball Mills
Authors: Burmeister Christine Friedericke , Kwade Arno
Published: October 2013

Review: 66 refs.
ChemInform Abstract: Mechanochemistry of Inorganic and Organic Systems: What Is Similar, what Is Different?
Authors: Boldyreva Elena
Published: October 2013

Review: 152 refs.
ChemInform Abstract: Hierarchical Zeolites Overcome All Obstacles: Next Stop Industrial Implementation
Authors: Verboekend Danny , Mitchell Sharon , Perez‐Ramirez Javier
Published: October 2013

Review: 38 refs.
ChemInform Abstract: Review of Melt Casting of Dense Ceramics and Glasses by High Gravity Combustion Synthesis
Authors: Liu G. H. , Li J. T. , Chen K. X.
Published: October 2013

Review: 63 refs.
ChemInform Abstract: Energy Disposition in Reactive Intermediates
Authors: Carpenter Barry K.
Published: October 2013

Review: 121 refs.
ChemInform Abstract: Interfacial Fabrication of Single‐Crystalline ZnTe Nanorods with High Blue Fluorescence.
Authors: Hou Linrui , Zhang Qiang , Ling Luting , Li Chen‐Xiong , Chen Li , Chen Su
Published: October 2013

The title nanorods are prepared by reaction of zinc acrylate dispersed in toluene with an aqueous solution of NaHTe in the presence of oleic acid as capping ligand at the toluene/water interface (90 °C, 4 h).
ChemInform Abstract: Novel Bifunctional Thiourea—Ammonium Salt Catalysts Derived from Amino Acids: Application to Highly Enantio‐ and Diastereoselective Aza‐Henry Reaction.
Authors: Wang Hong‐Yu , Cai Zhuo , Zhao Gang
Published: October 2013

A novel type of bifunctional thiourea‐ammonium salt is developed and their use as chiral phase‐transfer catalyst in aza‐Henry reactions between amidosulfones and nitroalkanes is demonstrated.
ChemInform Abstract: Solvent Free Hydrostannation and Stille Reactions Using Ionic Liquid Supported Organotin Reagents.
Authors: Faye Djibril , Vybornyi Mykhailo , Boeda Fabien , Legoupy Stephanie
Published: October 2013

The title organotin reagent (I) is amenable to hydrostannation of alkynes under radical conditions to yield mixtures of E/Z‐olefins (III)/(IV).
ChemInform Abstract: Copper‐Catalyzed Trifluoromethylation‐Initiated Radical 1,2‐Aryl Migration in α,α‐Diaryl Allylic Alcohols.
Authors: Liu Xiaowu , Xiong Fei , Huang Xuanping , Xu Liang , Li Pengfei , Wu Xiaoxing
Published: October 2013

The title reaction is demonstrated by conversion of 1,1‐diaryl allyl alcohols (I) by using Togni′s reagent (II) as CF3‐source to furnish trifluormethylated ketones (III) in good yields.
ChemInform Abstract: Iron‐Catalyzed Regio‐ and Stereoselective Conjugate Addition of Aryl‐Grignard Reagents to α,β,γ,δ‐Unsaturated Sulfones and Its Synthetic Application.
Authors: Hata Takeshi , Nakada Takuya , Oh Yun Taek , Hirone Naoki , Urabe Hirokazu
Published: October 2013

An Fe(II)‐catalyzed selective δ‐addition of aryl‐Grignard reagents to α,β,γ,δ‐unsaturated sulfones (I) is presented.
ChemInform Abstract: Iodine/Water‐Mediated Oxidation of o‐Alkynylaroyl Compounds and Application of the Products of Oxidation in the Synthesis of Nitrogen Heterocycles.
Authors: Sakthivel Karuppusamy , Srinivasan Kannupal
Published: October 2013

A facile iodine/water‐mediated oxidation of the triple bond of o‐alkynylaroyl compounds to furnish tricarbonyl products is reported.
ChemInform Abstract: Additive‐Controlled Regioselective Direct Asymmetric Aldol Reaction of Hydroxyacetone and Aldehyde.
Authors: Liu Ling‐yan , Wang Bing , Zhu Yunna , Chang Wei‐xing , Li Jing
Published: October 2013

A novel dipeptide derivative is employed as the catalyst for the direct asymmetric aldol reaction of hydroxyacetone and various aldehydes.
ChemInform Abstract: Organocatalytic Diastereo‐ and Enantioselective Sulfa‐Michael Addition to α,β‐Disubstituted Nitroalkenes.
Authors: Pei Qing‐Lan , Han Wen‐Yong , Wu Zhi‐Jun , Zhang Xiao‐Mei , Yuan Wei‐Cheng
Published: October 2013

The preparation of thiols (III) proceeds with reasonable diastereo‐ and enantioselectivity.
ChemInform Abstract: Highly Efficient Synthesis of Spiro[oxazolidine‐2‐thione‐oxindoles] with 3‐Isothiocyanato Oxindoles and Aldehydes via an Organocatalytic Cascade Aldol‐Cyclization Reaction.
Authors: Chen Wen‐Bing , Han Wen‐Yong , Han Yan‐Yan , Zhang Xiao‐Mei , Yuan Wei‐Cheng
Published: October 2013

Optimized conditions including optically active thioureas allow the synthesis of the title compounds in very short reaction times.
ChemInform Abstract: Copper‐Catalyzed Rearrangement of N‐Aryl Nitrones into Epoxyketimines.
Authors: Mo Dong‐Liang , Anderson Laura L.
Published: October 2013

α,β‐Unsaturated nitrones (I) and (IV) undergo Cu(I)‐catalyzed oxygen‐atom transfer reaction to give α,β‐epoxyketimines, generally with excellent trans‐diastereoselectivity.
ChemInform Abstract: A Concise Synthesis of 3,4‐Fused Spiro[isobenzofuran‐3‐ones], Spiro[furo[3,4‐b]pyridin‐5(7H)‐ones], 3‐Aryl‐, and Alkylphthalides.
Authors: Kuethe Jeffrey T. , Maloney Kevin M.
Published: October 2013

An efficient one‐pot Barbier reaction between 2‐iodobenzoic acid esters and ketones or aldehydes is presented using generally iPrMgCl·LiCl or less often BuLi as the base.The methodology is extended to the use of o‐iodonitriles, analogous pyridine esters or nitriles as well as an o‐iodoindole ester as substrates.
ChemInform Abstract: L‐Proline Catalyzed Reaction of N‐Confused Porphyrin and Active Methylene Compounds.
Authors: Liu Bin , Li Xiaofang , Zhang Jie , Chmielewski Piotr J.
Published: October 2013

L‐Proline as catalyst facilitates the formation of the carbanion derived from an active methylene compound, while simultaneously delivering protons to the N‐confused porphyrin.
ChemInform Abstract: Direct Regio‐, Diastereo‐, and Enantioselective Vinylogous Michael Addition of Prochiral 3‐Alkylideneoxindoles to Nitroolefins.
Authors: Rassu Gloria , Zambrano Vincenzo , Pinna Luigi , Curti Claudio , Battistini Lucia , Sartori Andrea , Pelosi Giorgio , Zanardi Franca , Casiraghi Giovanni
Published: October 2013

The asymmetric Michael addition of prochiral 3‐alkylideneoxindoles to nitroolefins is realized in the presence of a dihydroquinine derived thiourea catalyst.
ChemInform Abstract: Ring‐Rearrangement Metathesis of 7‐Azanorbornenes as an Entry to 1‐Azabicyclo[n.3.0]alkenones.
Authors: Rojas Victor , Carreras Javier , Avenoza Alberto , Busto Jesus H. , Peregrina Jesus M.
Published: October 2013

This metathesis reaction of the title bornenes allows the construction of pyrrolizidine, indolizidine, and pyrrolo[1,2‐α]azepine cores.
ChemInform Abstract: A Robust Protocol for Pd(II)‐Catalyzed C‐3 Arylation of (1H) Indazoles and Pyrazoles: Total Synthesis of Nigellidine Hydrobromide.
Authors: Ye Mengchun , Edmunds Andrew J. F. , Morris James A. , Sale David , Zhang Yejia , Yu Jin‐Quan
Published: October 2013

A practical synthesis of a wide range of 3‐arylated indazoles and pyrazoles including the biologically active agent YD‐3 (VIIc) is developed.
ChemInform Abstract: An Efficient Preparation of 2‐Alkyl‐oxazoles from 2‐Iodooxazoles.
Authors: Zhang Xing , Liu Jun , Liu Yi , Du Yuguo
Published: October 2013

An efficient method for the synthesis of 2‐alkyl substituted oxazoles (III) via alkylborane mediated Suzuki‐coupling is described.
ChemInform Abstract: An Efficient Method of Synthesis of Isoxazolidine‐Fused β‐Lactams via Base‐Promoted Cyclization—Ring Opening of Carbamoylspirocyclopropane Isoxazolidines.
Authors: Tran Tung Q. , Savinkov Ruslan S. , Diev Vyacheslav V. , Starova Galina L. , Molchanov Alexander P.
Published: October 2013

A novel type of β‐lactame derivatives (IV) can be synthesized by base‐promoted cyclization‐cyclopropane ring opening of isoxazolidines (III) which in turn are readily prepared by 1,3‐dipolar cycloaddition of C‐carbamoyl nitrones (I) with methylenecyclopropanes (II).
ChemInform Abstract: Synthesis and Biological Evaluation of Novel Bis[1,2,4]triazolo[3,4‐b][1,3,4]oxadiazoles.
Authors: Reddy Ch. Sanjeeva , Devi M. Vani , Kumar G. Rajesh , Sunitha M. , Nagaraj A.
Published: October 2013

Newly synthesized title compounds (VII) are screened for their activity against a panel of Gram‐positive bacteria.
ChemInform Abstract: Synthesis and Spectra Characteristics of Novel 3‐(para‐Bromophenyl)‐7‐(substituted vinyl) Coumarins.
Authors: Wang Lingyun , Zou Hanxun , Ye Decheng , Cao Derong
Published: October 2013

Novel coumarin derivatives (I) are synthesized via Perkin condensation and Wittig olefination.
ChemInform Abstract: Oxidative Olefination of Secondary Amines with Carbon Nucleophiles.
Authors: Zhang Yong‐Gang , Xu Jing‐Kun , Li Xi‐Ming , Tian Shi‐Kai
Published: October 2013

This is an highly E‐selective olefination under metal‐free oxidative conditions.
ChemInform Abstract: Chiral Organic Contact Ion Pairs in Metal‐Free Catalytic Enantioselective Oxidative Cross‐Dehydrogenative Coupling of Tertiary Amines to Ketones.
Authors: Zhang Gen , Ma Yunxia , Wang Shoulei , Kong Weidong , Wang Rui
Published: October 2013

This novel, efficient, and environmentally friendly title reaction affords tetrahydroisoquinoline derivatives from simple starting materials and under mild conditions in satisfactory yields with good diastereo‐ and enantioselectivities.
ChemInform Abstract: Synthesis of Fluorine‐Containing Multisubstituted Phenanthridines by Rhodium‐Catalyzed Alkyne [2 + 2 + 2] Cycloaddition and Tandem sp2 C—H Difluoromethylenation.
Authors: Li Yajun , Zhu Jiangtao , Zhang Lisi , Wu Yongming , Gong Yuefa
Published: October 2013

Phenanthridines (III) and (V) are obtained by Rh‐catalyzed diyne cycloaddition reactions, offering a mild and direct method for the construction of multisubstituted phenanthridines with good functional group tolerance.
ChemInform Abstract: Contrasting Behavior of NBS Towards 1,4‐Dihydrobenzothieno[3,2‐b]pyridine 5,5‐Dioxides and 4,5‐Dihydro‐1H‐indeno[1,2‐b]pyridines.
Authors: Sobolev Arkadij , et al. et al.
Published: October 2013

Benzothienopyridine dioxides (I) react with NBS under mild conditions to yield fully aromatized products (II) directly whereas the analogous indenones (III) give stable bromides (IV) which are not prone to dehydrobromination.
ChemInform Abstract: Stereoselective Synthesis of 2,5‐Disubstituted Morpholines Using a Palladium‐Catalyzed Hydroamination Reaction.
Authors: McGhee Alicia , Cochran Brian M. , Stenmark Torrey A. , Michael Forrest E.
Published: October 2013

The regioselective opening of aziridines (I) with allyl alcohol proceeds readily in the presence of a Lewis acid.
ChemInform Abstract: Synthesis of Novel 2,4‐Disubstituted 3H‐Pyrido[3,2‐e][1,4]diazepin‐5‐ones and 2,4‐Disubstituted 3H‐Pyrido[2,3‐e][1,4]diazepin‐5‐ones Derivatives via Regioselective Thionation and Nucleophilic Substitutions Reactions.
Authors: El Bouakher Abderrahman , Prie Gildas , Aadil Mina , Akssira Mohamed , Viaud‐Massuard Marie‐Claude
Published: October 2013

The synthesis of the title compounds (VI) as potentially pharmacologically relevant structures is detailed.
ChemInform Abstract: New Phosphine Oxide Aziridinyl Phosphonates as Chiral Lewis Bases for the Abramov‐Type Phosphonylation of Aldehydes.
Authors: Dogan Oezdemir , Isci Muhammet , Aygun Muhittin
Published: October 2013

Newly synthesized chiral aziridine bisphosphonates are examined for the phosphonylation of aldehydes.
ChemInform Abstract: Potassium tert‐Butoxide‐Mediated Synthesis of Unsymmetrical Diaryl Ethers, Sulfides and Selenides from Aryl Bromides.
Authors: Kumar Amit , Bhakuni Bhagat Singh , Prasad Ch. Durga , Kumar Shailesh , Kumar Sangit
Published: October 2013

KOtBu In DMSO can be efficiently used for the synthesis of unsymmetrical diaryl sulfides and selenides from diaryl dichalcogenides and aryl bromides.
ChemInform Abstract: Synthesis of 2,6‐Disubstituted Pyridin‐3‐yl C‐2′‐Deoxyribonucleosides Through Chemoselective Transformations of Bromo‐chloropyridine C‐Nucleosides.
Authors: Kubelka Tomas , Slavetinska Lenka , Eigner Vaclav , Hocek Michal
Published: October 2013

Standard Pd‐catalyzed cross‐coupling reactions proceed chemoselectively at the position of the bromine, whereas nucleophilic substitutions are unselective.
ChemInform Abstract: Hydrogen Peroxide Activation over TiIV: What Have We Learned from Studies on Ti‐Containing Polyoxometalates?
Authors: Kholdeeva Oxana A.
Published: October 2013

Review: [<60refs.]
ChemInform Abstract: Sulfite Anions as Structure‐Directing Templates for the Engineering of Modular Polyoxometalates
Authors: Miras Haralampos N. , Chilas George I. , Cronin Leroy , Kabanos Themistoklis A.
Published: October 2013

Review: ≈50 refs.
ChemInform Abstract: Routes to Nanostructured Inorganic Materials with Potential for Solar Energy Applications
Authors: Ramasamy Karthik , Malik Mohammad Azad , Revaprasadu Neerish , O'Brien Paul
Published: October 2013

Review: 238 refs.
ChemInform Abstract: Chemical Structure, Biosynthesis and Synthesis of Free and Glycosylated Pyridinolines Formed by Cross‐Link of Bone and Synovium Collagen
Authors: Anastasia Luigi , Rota Paola , Anastasia Mario , Allevi Pietro
Published: October 2013

Review: 130 refs.
ChemInform Abstract: Studies of Reactions Relevant to Astrochemistry
Authors: Costes Michel , Naulin Christian
Published: October 2013

Review: 97 refs.
ChemInform Abstract: Carbene Additions to Fullerenes
Authors: Yamada Michio , Akasaka Takeshi , Nagase Shigeru
Published: October 2013

Review: 431 refs.
ChemInform Abstract: Principles of Cation‐π Interactions in Supramolecular Chemistry
Authors: Ostrowski Wojciech , Franski Rafal
Published: October 2013

Review: 35 refs.
Causes of retrograde flow in fish keratocytes
Authors: Fuhs Thomas , Goegler Michael , Brunner Claudia A. , Wolgemuth Charles W. , Kaes Josef A.
Published: October 2013

Confronting motile cells with obstacles doubling as force sensors we tested the limits of the driving actin and myosin machinery. We could directly measure the force necessary to stop actin polymerization as well as the force present in the retrograde actin flow. Combined with detailed measurements of the retrograde flow velocity and specific manipulation of actin and myosin we found that actin polymerization and myosin contractility are not enough to explain the cells behavior. We show that ever‐present depolymerization forces, a direct entropic consequence of actin filament recycling, are sufficient to fill this gap, even under heavy loads. © 2013 Wiley Periodicals, Inc.
Design and Generation of Highly Diverse Fluorinated Fragment Libraries and their Efficient Screening with Improved 19F NMR Methodology
Authors: Vulpetti Anna , Dalvit Claudio
Published: October 2013

Fragment screening performed with 19F NMR spectroscopy is becoming increasingly popular in drug discovery projects. With this approach, libraries of fluorinated fragments are first screened using the direct‐mode format of the assay. The choice of fluorinated motifs present in the library is fundamental in order to ensure a large coverage of chemical space and local environment of fluorine (LEF). Mono‐ and poly‐fluorinated fragments to be included in the libraries for screening are selected from both in‐house and commercial collections, and those that are ad hoc designed and synthesized. Additional fluorinated motifs to be included in the libraries derive from the fragmentation of compounds in development and launched on the market, and compounds contained in other databases (such as Integrity, PDB and ChEMBL). Complex mixtures of highly diverse fluorine motifs can be rapidly screened and deconvoluted in the same NMR tube with a novel on the fly combined procedure for the identification of the active molecule(s). Issues and problems encountered in the design, generation and screening of diverse fragment libraries of fluorinated compounds with 19F NMR spectroscopy are analyzed and technical solutions are provided to overcome them. The versatile screening methodology described here can be efficiently applied in laboratories with limited NMR setup and could potentially lead to the increasing role of 19F NMR in the hit identification and lead optimization phases of drug discovery projects.
Evaluation of endobronchial ultrasound‐guided fine‐needle aspirations (EBUS‐FNA): Correlation with adequacy and histologic follow‐up
Authors: Karunamurthy Arivarasan , Cai Guoping , Dacic Sanja , Khalbuss Walid E. , Pantanowitz Liron , Monaco Sara E.
Published: October 2013

BACKGROUND

Endobronchial ultrasound‐guided fine‐needle aspiration (EBUS‐FNA) is a minimally invasive modality for diagnosing mediastinal lesions. When determining adequacy, EBUS‐FNAs are evaluated for diagnostic material or sufficient lymphoid tissue. In this study, the authors evaluated their experience with EBUS‐FNAs and correlated the findings with adequacy and histologic follow‐up.

METHODS

EBUS‐FNAs were retrospectively reviewed over a 3‐year period and correlated with the clinicopathologic findings, adequacy, and histologic follow‐up.

RESULTS

In total, 593 EBUS‐FNAs were obtained from 356 patients, including 420 (71%) satisfactory (SAT) cases, 107 (18%) less than optimal (LTO) cases, and 66 (11%) unsatisfactory (UNSAT) cases. The overall diagnostic yield was 71%, and the mediastinal (N2) lymph nodes had better yield (72%) than the peripheral intrapulmonary and hilar (N1) lymph nodes (64%). Histologic follow‐up was available in 203 cases (34%), and malignancy was identified in 7 UNSAT cases (23%), 6 LTO‐negative cases (11%), and 4 SAT cases (3%) with a negative cytologic diagnosis. In the suboptimal cases with follow‐up, 79% were benign and 21% were malignant on follow‐up, including 25 (14%) with fibrosis or hyalinization. The sensitivity, specificity, and positive and negative predictive values in the study were 80%, 100%, 100%, and 95%, respectively.

CONCLUSIONS

The current data demonstrated that EBUS‐FNA has good sensitivity, high specificity, and a higher diagnostic yield for N2 lymph nodes compared with N1 lymph nodes. The data also illustrate the finding that suboptimal cases have a greater risk of false‐negative diagnoses and a 21% chance of malignancy, including processes with fibrosis or hyalinization. Cancer (Cancer Cytopathol) 2014;122:23–32. © 2013 American Cancer Society.
A new efficient method for synaptic vesicle quantification reveals differences between medial prefrontal cortex perforated and nonperforated synapses
Authors: Nava Nicoletta , Chen Fenghua , Wegener Gregers , Popoli Maurizio , Nyengaard Jens Randel
Published: October 2013

Communication between neurons is mediated by the release of neurotransmitter‐containing vesicles from presynaptic terminals. Quantitative characterization of synaptic vesicles can be highly valuable for understanding mechanisms underlying synaptic function and plasticity. We performed a quantitative ultrastructural analysis of cortical excitatory synapses by mean of a new, efficient method, as an alternative to three‐dimensional (3D) reconstruction. Based on a hierarchical sampling strategy and unequivocal identification of the region of interest, serial sections from excitatory synapses of medial prefrontal cortex (mPFC) of six Sprague‐Dawley rats were acquired with a transmission electron microscope. Unbiased estimates of total 3D volume of synaptic terminals were obtained through the Cavalieri estimator, and adequate correction factors for vesicle profile number estimation were applied for final vesicle quantification. Our analysis was based on 79 excitatory synapses, nonperforated (NPSs) and perforated (PSs) subtypes. We found that total number of docked and reserve‐pool vesicles in PSs significantly exceeded that in NPSs (by, respectively, 77% and 78%). These differences were found to be related to changes in size between the two subtypes (active zone area by 86%; bouton volume by 105%) rather than to postsynaptic density shape. Positive significant correlations were found between number of docked and reserve‐pool vesicles, active zone area and docked vesicles, and bouton volume and reserve pool vesicles. Our method confirmed the large size of mPFC PSs and a linear correlation between presynaptic features of typical hippocampal synapses. Moreover, a greater number of docked vesicles in PSs may promote a high synaptic strength of these synapses. J. Comp. Neurol. 522:284–297, 2014. © 2013 Wiley Periodicals, Inc.
Scalable, privacy preserving radio‐frequency identification protocol for the internet of things
Authors: Asadpour Mahdi , Dashti Mohammad Torabi
Published: October 2013

It is now possible to embed radio‐frequency identification tags into almost any physical device. However, issues regarding privacy remain a concern and limit their widespread use. We propose a scalable anonymous radio‐frequency identification authentication protocol using what we refer to as anonymous tickets. These tickets uniquely identify tags and are reusable. This considerably strengthens its non‐traceability and requires just search/query time, with minimal storage overhead on the back‐end system. We formally prove the protocol and compare the performance of the proposed protocol with selected works found in literature. Copyright © 2013 John Wiley & Sons, Ltd.
Helical Self‐Assembly of Optically Active Phthalocyanine Derivatives: Effect of ZnO Coordination Bond on Morphology and Handedness of Nanostructures
Authors: Zhang Congcong , Jing Lu , Lin Sha , Hao Zijuan , Tian Jing , Zhang Xiaomei , Zhu Peihua
Published: October 2013

Two optically active phthalocyanine derivatives with eight peripheral chiral (S)‐4′‐(2‐methylbutoxy)biphenyl moieties on the β‐position of the phthalocyanine ring are synthesized. The circular dichroism (CD) spectra show signals in the Q absorption region for both compounds 1 and 2 in chloroform solution, indicating the effective chiral‐information transfer from the peripheral chiral (S)‐4′‐(2‐methylbutoxy)biphenyl side chains to the phthalocyanine chromophore at the molecular level. Their self‐assembling properties are further investigated by using electronic absorption and Fourier transform infrared spectroscopy, transmission electronic microscopy, scanning electronic microscopy, X‐ray diffraction, and X‐ray photoelectron spectroscopy. Experimental results reveal the effect of the metal‐coordination bond on molecular packing models in these nanostructures, which in turn results in the self‐assembled nanostructures with different morphologies, from nanosheets for 1 to helical nanofibers for 2. In addition, good semiconducting properties of the nanostructures fabricated from phthalocyanine derivatives 1 and 2 are revealed by current–voltage measurements.
Quantification of Hydrogen Sulfide and Methanethiol and the Study of Their Scavenging by Biocides of the Isothiazolone Family
Authors: Frerot Eric , Bagnoud Alain , Cicchetti Esmeralda
Published: October 2013

A sensitive analytical method for the quantification of malodourous hydrogen sulfide (H2S) and methanethiol (CH3SH) was developed and validated. The method consisted of solid‐phase microextraction with concomitant in‐fibre derivatisation of the mercaptan using N‐ethylmaleimide. The adducts were analysed by GC–MS using a triple quadrupole in the selected reaction monitoring mode. The limits of detection of solutions of H2S and CH3SH in water were 100 and 10 ng L−1, respectively, below their odour‐perception thresholds. The analytical method was used to show the scavenging effect of 1,2‐benzisothiazol‐3(2H)‐one (Proxel) and 2‐methyl‐4‐isothiazolinone. The mechanism by which H2S and CH3SH are trapped with Proxel was studied by ultraperformance liquid chromatography (UPLC)‐MS.
Mixed Co–Mn Oxide‐Catalysed Selective Aerobic Oxidation of Vanillyl Alcohol to Vanillin in Base‐Free Conditions
Authors: Jha Ajay , Patil Kashinath R. , Rode Chandrashekhar V.
Published: October 2013

Manganese‐doped cobalt mixed oxide (MnCo‐MO) catalyst was prepared by a solvothermal method. The as‐prepared catalyst was characterised by X‐ray photoelectron spectroscopy, H2 temperature‐programmed reduction, O2 temperature‐programmed oxidation and XRD. This catalyst gave 62 % conversion with 83 % selectivity to vanillin in 2 hours for the liquid‐phase air oxidation of vanillyl alcohol without using base. Three different types of metal oxides were observed in the prepared catalyst, which could be identified as Co3O4, Mn3O4 and CoMn2O4. Among these, the tetragonal phase of CoMn2O4 was found to be more active and selective for vanillyl alcohol oxidation than Co3O4 and Mn3O4. High‐resolution TEM characterisation revealed the morphology of MnCo‐MO nanorods with a particle size of 10 nm. Successful recycling of the catalyst was also established in this oxidation reaction.
A methamphetamine analog (N,α‐diethyl‐phenylethylamine) identified in a mainstream dietary supplement
Authors: Cohen Pieter A. , Travis John C. , Venhuis Bastiaan J.
Published: October 2013

Pharmaceuticals and banned substances have been detected in hundreds of purportedly natural supplements. Recently, several athletes have been disqualified from competition after testing positive for the methamphetamine analog N,α‐diethyl‐phenylethylamine (N,α‐DEPEA). Athletes have claimed they unknowingly consumed the banned stimulant in workout supplements. Three samples from different lot numbers of Craze, a workout supplement, were analyzed to detect the presence and concentration of N,α‐DEPEA. Two labs independently identified N,α‐DEPEA in the supplement using ultra high performance liquid chromatography (UHPLC) coupled to an LTQ Orbitrap XL mass spectrometer and UHPLC‐quadruple‐time‐of‐flight mass (Q‐TOF) spectrometer, respectively. The identity of N,α‐DEPEA was confirmed using nuclear magnetic resonance and reference standards. Manufacturer recommended servings were estimated to provide 21 to 35 mg of N,α‐DEPEA. N,α‐DEPEA has never been studied in humans. N,α‐DEPEA is a methamphetamine analog; however, its stimulant, addictive and other adverse effects in humans are entirely unknown. Regulatory agencies should act expeditiously to warn consumers and remove N,α‐DEPEA from all dietary supplements. Copyright © 2013 John Wiley & Sons, Ltd.
Study on Oxidation State Dependent Electrocatalytic Ability for I−/I3− Redox Reaction of Reduced Graphene Oxides
Authors: Yeh Min‐Hsin , Lin Lu‐Yin , Huang Tzu‐Yen , Chuang Hui‐Min , Chu Chih‐Wei , Ho Kuo‐Chuan
Published: October 2013

The influence of oxidation states on electrocatalytic abilities for I3− reduction is discussed for reduced graphene oxide (rGO), which is a promising catalyst of counter electrodes for dye‐sensitized solar cells (DSSCs). The oxidation states of rGO can be controlled via a photothermal reduction process by varying exposure times. The results reveal that the rGO with lower oxidation state shows smaller charge transfer resistance at the electrode/electrolyte interface and better electrocatalytic ability attributed to higher standard heterogeneous rate constant (k0) and reasonable electrochemical surface area (Ae) for I3− reduction, both are quantitatively determined by a rotating disk electrode system using the KouteckýLevich equation.
Electrochemical Detection of TNT at Cobalt Phthalocyanine Mediated Screen‐Printed Electrodes and Application to Detection of Airborne Vapours
Authors: Caygill J. Sarah , Collyer Stuart D. , Holmes Joanne L. , Davis Frank , Higson Séamus P. J.
Published: October 2013

We describe the use of cobalt phthalocyanine as a mediator to improve the sensitivity for the electrochemical detection of TNT. Commercial screen‐printed electrodes containing cobalt phthalocyanine were employed for determination of TNT. Improved sensitivities compared to screen‐printed carbon electrodes without phthalocyanine were observed, current response for cyclic voltammetric measurements at modified electrodes being at least double that of unmodified electrodes. A synergistic effect between oxygen and TNT reduction was also observed. Correlation between TNT concentrations and sensor output was observed between 0–200 µM TNT. Initial proof‐of‐concept experiments combining electrochemical determinations, with the use of an air‐sampling cyclone, are also reported.
A nonconforming finite element method for the Stokes equations using the Crouzeix‐Raviart element for the velocity and the standard linear element for the pressure
Authors: Lamichhane Bishnu P.
Published: October 2013

We present a finite element method for Stokes equations using the Crouzeix‐Raviart element for the velocity and the continuous linear element for the pressure. We show that the inf‐sup condition is satisfied for this pair. Two numerical experiments are presented to support the theoretical results. Copyright © 2013 John Wiley & Sons, Ltd.