bluuebunny/crossref_metadata_2025 huggingface dataset:
Phonological and Semantic Fluency in Alzheimer’s Disease: A Systematic Review and Meta-Analysis
Authors: Olmos-Villaseñor Rocio , Sepulveda-Silva Consuelo , Julio-Ramos Teresa , Fuentes-Lopez Eduardo , Toloza-Ramirez David , Santibañez Rodrigo A. , Copland David A. , Mendez-Orellana Carolina
Published: July 2023

Background:

Semantic and Phonological fluency (SF and PF) are routinely evaluated in patients with Alzheimer’s disease (AD). There are disagreements in the literature regarding which fluency task is more affected while developing AD. Most studies focus on SF assessment, given its connection with the temporoparietal amnesic system. PF is less reported, it is related to working memory, which is also impaired in probable and diagnosed AD. Differentiating between performance on these tasks might be informative in early AD diagnosis, providing an accurate linguistic profile.

Objective:

Compare SF and PF performance in healthy volunteers, volunteers with probable AD, and patients with AD diagnosis, considering the heterogeneity of age, gender, and educational level variables.

Methods:

A total of 8 studies were included for meta-analysis, reaching a sample size of 1,270 individuals (568 patients diagnosed with AD, 340 with probable AD diagnosis, and 362 healthy volunteers).

Results:

The three groups consistently performed better on SF than PF. When progressing to a diagnosis of AD, we observed a significant difference in SF and PF performance across our 3 groups of interest ( p = 0.04). The age variable explained a proportion of this difference in task performance across the groups, and as age increases, both tasks equally worsen.

Conclusion:

The performance of SF and PF might play a differential role in early AD diagnosis. These tasks rely on partially different neural bases of language processing. They are thus worth exploring independently in diagnosing normal aging and its transition to pathological stages, including probable and diagnosed AD.
Association Between Neuroticism and Dementia on Healthcare Use: A Multi-Level Analysis Across 27 Countries from The Survey of Health, Ageing and Retirement in Europe (SHARE)
Authors: Ruiz-Adame Manuel , Ibañez Agustín , Mollayeva Tatyana , Trépel Dominic
Published: July 2023

Background:

People with high levels of neuroticism are greater users of health services. Similarly, people with dementia have a higher risk of hospitalization and medical visits. As a result, dementia and a high level of neuroticism increase healthcare use (HCU). However, how these joint factors impact the HCU at the population level is unknown. Similarly, no previous study has assessed the degree of generalization of such impacts, considering relevant variables including age, gender, socioeconomic, and country-level variability.

Objective:

To examine how neuroticism and dementia interact in the HCU.

Methods:

A cross-sectional study was performed on a sample of 76,561 people (2.4% with dementia) from 27 European countries and Israel. Data were analyzed with six steps multilevel non-binomial regression modeling, a statistical method that accounts for correlation in the data taken within the same participant.

Results:

Both dementia (Incidence Rate Ratio (IRR): 1.537; α= 0.000) and neuroticism (IRR: 1.122; α= 0.000) increased the HCU. The effect of having dementia and the level of neuroticism increased the HCU: around 53.67% for the case of having dementia, and 12.05% for each increment in the level of neuroticism. Conversely, high levels of neuroticism in dementia decreased HCU (IRR: 0.962; α= 0.073). These results remained robust when controlling for age, gender, socioeconomic, and country-levels effects.

Conclusion:

Contrary to previous findings, neuroticism trait in people with dementia decreases the HCU across sociodemographic, socioeconomic, and country heterogeneity. These results, which take into account this personality trait among people with dementia, are relevant for the planning of health and social services.
Incidence of Alzheimer’s Disease in Men with Late-Life Hypertension Is Ameliorated by FOXO3 Longevity Genotype
Authors: Chen Randi , Morris Brian J. , Donlon Timothy A. , Ross G. Webster , Kallianpur Kalpana J. , Allsopp Richard C. , Nakagawa Kazuma , Willcox Bradley J. , Masaki Kamal H.
Published: July 2023

Background:

It is well established that mid-life hypertension increases risk of dementia, whereas the association of late-life hypertension with dementia is unclear.

Objective:

To determine whether FOXO3 longevity-associated genotype influences the association between late-life hypertension and incident dementia.

Methods:

Subjects were 2,688 American men of Japanese ancestry (baseline age: 77.0±4.1 years, range 71–93 years) from the Kuakini Honolulu Heart Program. Status was known for FOXO3 rs2802292 genotype, hypertension, and diagnosis of incident dementia to 2012. Association of FOXO3 genotype with late-life hypertension and incident dementia, vascular dementia (VaD) and Alzheimer’s disease (AD) was assessed using Cox proportional hazards models.

Results:

During 21 years of follow-up, 725 men were diagnosed with all-cause dementia, 513 with AD, and 104 with VaD. A multivariable Cox model, adjusting for age, education, APOE ɛ4, and cardiovascular risk factors, showed late-life hypertension increased VaD risk only (HR = 1.71, 95% CI = 1.08–2.71, p = 0.022). We found no significant protective effect of FOXO3 longevity genotype on any type of dementia at the population level. However, in a full Cox model adjusting for age, education, APOE ɛ4, and other cardiovascular risk factors, there was a significant interaction effect of late-life hypertension and FOXO3 longevity genotype on incident AD ( β= –0.52, p = 0.0061). In men with FOXO3 rs2802292 longevity genotype ( TG/ GG), late-life hypertension showed protection against AD (HR = 0.72; 95% CI = 0.55–0.95, p = 0.021). The non-longevity genotype ( TT) (HR = 1.16; 95% CI = 0.90–1.51, p = 0.25) had no protective effect.

Conclusion:

This longitudinal study found late-life hypertension was associated with lower incident AD in subjects with FOXO3 genotype.
Designing and manufacturing custom-made 3D printed assistive devices: A comparison of three workflows
Authors: Slegers Karin , Delien Tessa , Bettelli Valentina , Lexis Monique , Saey Tom , Banes David , Daniëls Ramon
Published: July 2023

BACKGROUND:

Do-it-yourself technologies such as 3D printing offer interesting opportunities for creating custom-made assistive devices for people with disabilities. Although these opportunities are increasingly acknowledged, it remains unclear how 3D printing technology should be implemented in assistive devices delivery processes.

OBJECTIVE:

In three separate action research projects carried out in Belgium, Italy and The Netherlands, workflows were designed and evaluated that incorporate 3D printing as a standard option for providing clients with suitable assistive devices.

METHODS:

In this paper we describe and compare the three workflows that were conceived simultaneously, yet independently from each other.

RESULTS:

Based on the evaluations of these workflows, and the experiences of the researchers who developed the workflows, we provide recommendations for implementing 3D printing as a common approach in assistive device delivery processes in practice. Most importantly, designing and manufacturing should be done by means of a client-centered co-creation process by interdisciplinary teams of clinicians, clients, and 3D printing experts. We provide several recommendations for facilitating and supporting collaborations within such teams.

CONCLUSIONS:

The three workflows presented in this paper are strikingly similar and therefore provide a convincing starting point for interdisciplinary design teams who wish to embark on 3D printing custom-made assistive devices.
How does digital life influence the health service use among rural residents? Evidence from China
Authors: Zhou Deshui , Zhan Qianqian , Wen Xin
Published: July 2023

BACKGROUND: The Healthy China strategy is an important development objective of the 14th Five-Year Plan and Vision 2035 in China, while health service use in rural China has been a weak link in this strategy. OBJECTIVE: Nowadays, people’s health service use will be influenced by digital technology due to the arrival of the Digital Age, and that is the reason why our interest is to discuss the effect of digital life on health service use among rural residents. METHODS: We use the data from the China Family Panel Studies (CFPS) 2020 to examine the effect of digital life on health service use among rural residents, and we use Instrumental Variables method to control the endogenous problem and use KHB model to discuss the mechanism of this effect. RESULTS: It was found that digital life has increased the health service use among rural residents significantly, and this result has been verified by robust test and Instrumental Variables method. Besides, digital life can increase health service use through the information channel effect and the health literacy effect indirectly. Moreover, digital life has a more significant impact on the residents with low social capital, low physical capital and low social trust, which represents the inclusivity of digital life. CONCLUSION: The results of our paper will be helpful to examine the effect of the digital policy on promoting the health service use in rural China, and our findings will provide evidence of how to use digital life to enhance health service use among rural residents. Based on this, the government should take measures to eliminate the digital divide between urban and rural areas by promoting the level of digital life among rural residents, paying more attention to the digital literacy development among them, and forging ahead toward the great goal of the Healthy China under the Digital Age.
Comparative evaluation of stroke volume variation measured by pulse wave transit time and arterial pressure wave
Authors: Ochiai Ryoichi , Terada Takashi , Sakamoto Noriaki
Published: July 2023

BACKGROUND: Several monitors have been developed that measure stroke volume (SV) in a beat-to-beat manner. Accordingly, Stroke volume variation (SVV) induced by positive pressure ventilation is widely used to predict fluid responsiveness. OBJECTIVE: The purpose of this study was to compare the ability of two different methods to predict fluid responsiveness using SVV, stroke volume variation by esCCO (esSVV) and stroke volume variation by FloTrac/VigileoTM (flSVV). METHODS: esSVV, flSVV, and stroke volume index (SVI) by both monitoring devices of 37 adult patients who underwent laparotomy surgery, were measured. Receiver operating characteristic (ROC) analysis was performed. RESULTS: The area under the ROC curve (AUC) of esSVV was significantly higher than that of flSVV (p= 0.030). esSVV and flSVV showed cutoff values of 6.1% and 10% respectively, to predict an increase of more than 10% in SVI after fluid challenge. The Youden index for esSVV was higher than flSVV, even with a cutoff value between 6% and 8%. CONCLUSION: Since esSVV and flSVV showed significant differences in AUC and cutoff values, the two systems were not comparable in predicting fluid responsiveness. Furthermore, it seems that SVV needs to be personalized to accurately predict fluid responsiveness for each patient.
An investigation on the changes of serum CCK-8, substance P, and 5-HT in patients with post-stroke insomnia
Authors: Zhang Xiao-Hua , Zhang Xin , Feng Hong-Ye , Cao Chang-Chun , Lv Hui-Lan , Wang Yu-Long , Ren Li-Jie
Published: July 2023

BACKGROUND: At present, the pathogenesis of post-stroke insomnia (PSI) is still inconclusive. OBJECTIVE: To explore the changes and significance of serum cholecystokinin-8 (CCK-8), substance P (SP), and 5-hydroxytryptamine (5-HT) in patients with PSI. METHODS: Ninety-one patients with stroke were selected as the research subjects, and according to the score of the Athens Insomnia Scale (AIS), they were divided into the insomnia group and the non-insomnia group. The serum levels of CCK-8, SP, and 5-HT in the two groups were compared to explore their relationships with PSI. RESULTS: Among the 91 patients, 56 were in the insomnia group and 35 were in the non-insomnia group, and the incidence of insomnia was 61.5%. There was no significant difference in the serum levels of CCK-8, SP, and 5-HT between the two groups (P= 0.696, 0.980, and 0.809, respectively). One-way analysis of variance showed that there was no significant correlation between the serum levels of CCK-8, SP, 5-HT, and the AIS score (P= 0.7393, 0.9581, and 0.5952, respectively). CONCLUSION: The incidence of PSI was relatively high, but it could not be proved that CCK-8, SP, and 5-HT were involved in the pathogenesis of PSI. There might exist other neurotransmitters involved in the pathophysiological process of PSI, which should be further explored.
An extensive review on crop/weed classification models
Authors: Panda Bikramaditya , Mishra Manoj Kumar , Mishra Bhabani Shankar Prasad , Tiwari Abhinandan Kumar
Published: July 2023

Crop and weed identification remains a challenge for unmanned weed control. Due to the small range between the chopping tine and the important crop location, weed identification against the annual crops must be extremely exact. This study endeavor included a literature evaluation, which included the most important 50 research publications in IEEE, Science Direct, and Springer journals. From 2012 until 2022, all of these papers are gathered. In fact, the diagnosis steps include: preprocessing, feature extraction, and crop/weed classification. This research analyzes the 50 research articles in several aspects, such as the dataset used for evaluations, different strategies used for pre-processing, feature extraction, and classification to get a clear picture of them. Furthermore, each work’s high performance in accuracy, sensitivity, and precision is demonstrated. Furthermore, the present hurdles in crop and weed identification are described, which serve as a benchmark for upcoming researchers.
Impact of Positive Emotions on the Willingness to Communicate in Second Language
Authors: Adnan Muhammad , Nadeem Muhammad Umar
Published: July 2023

Globally, second language (L2) education aims to empower the learners with skills and motivation necessary for effective communication. The current study investigated the association between ten positive emotions and the Willingness to Communicate (WTC) in L2. The emotions studied were joy, gratitude, interest, serenity, amusement, hope, pride, awe, inspiration, and love. While previous research conducted on this topic was largely confined to the Western context, this study incorporated the Pakistani context as well to establish a more comprehensive picture. Three hundred (300) undergraduate and postgraduate students enrolled in higher education institutions (HEIs) in Islamabad, Pakistan took part in the research. The findings revealed that gratitude, pride, hope, inspiration, and amusement tend to impact students’ WTC in L2. The results offer many practical insights for policymakers, teachers, and higher education students. HEIs may develop/conduct a variety of policies, strategies, initiatives, trainings, and workshops to address L2 communication based on the findings of this research.
Validation of Healthy Aging Brain Care Monitor Selfreport Questionnaire in Patients With Post-intensive Care Syndrome
Authors:   Nursing Care Research Center in Chronic Disease, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Ahmadi Mehdi Bahran , Jahani Simin ,   Department of Medical and Surgical Nursing, Nursing Care Research Center in Chronic Disease, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Elhaee Amir ,   Department of Biostatics and Epidemiology, School of Health, Mazandaran University of Medical Sciences, Mazandaran, Iran., Sayadi Neda ,   Department of Biostatics and Epidemiology, School of Health, Mazandaran University of Medical Sciences, Mazandaran, Iran.
Published: July 2023

Background: Many survivors of intensive care units experience functional disabilities and significant physical, mental, and perceptive impairments known as post-intensive care syndrome (PICS). Objectives: This research intended to translate and examine the psychometric properties of the Persian version of the healthy aging brain care monitor self-report (HABC-M-SR). Materials & Methods: This methodological research was directed to ascertain the psychometric properties of the Persian version of HABC-M-SR (p-HABC). This study was conducted in Ahvaz City, Iran, in 2021. The HABC-M-SR was translated into Persian. Face validity, content validity index, and content validity ratio were examined. Exploratory and confirmatory factor analyses were performed on 500 samples. The Cronbach α and interclass correlation coefficients were calculated to check the reliability. Results: Regarding the quantitative and qualitative face and content validity assessments, all items were suitable for further analysis, with a content validity index >0.79 and a content validity ratio >0.62. Afterward, exploratory factor analysis was implemented on 270 subjects assuming that three factors were constant on the questionnaire. Also, questions 7, 8, 9, and 12 were removed due to low factor loading, and confirmatory factor analysis was performed on 23 questions. Finally, 230 samples were taken, and the results were almost within the acceptable range. The Cronbach α (0.828) and interclass correlation coefficient (0.752) were satisfactory results. Conclusion: The p-HABC showed acceptable psychometric properties and can be used to screen for PICS. The p-HABC can trigger further studies on early diagnosis and management of PICS in ICU survivors in Iran.
ECONOMIC IMPACT OF WAR FOR UKRAINE, EUROPE AND GLOBAL WORLD
Authors:   Kharkiv National University of Radioelectronics, Sheiko Iryna , Storozhenko Oleksandra ,   Kharkiv National University of Radioelectronics, Kurdenko Oleksandr ,   Kharkiv National University of Radioelectronics
Published: July 2023

This article analyzes the economic consequences of Russia’s military aggression for directly fighting Ukraine, as well as Europe and the global world. Based on the analysis of statistical reports of international agencies, it was determined that the most significant challenges for the economic life of the countries were the increase in prices, especially for food and energy products, the slowdown in GDP growth, and the increase in the level of indebtedness of the countries. Countries with a low level of income and a high share of food costs in the family budget suffer the most from the increase in food prices. Also inflation dynamics for EU countries was analyzed. It was noted that Ukraine suffered the most from military actions, and therefore the country needs a clear and detailed plan of actions for post-war reconstruction. The main requirements for recovery programs are outlined: urgency, coordination between donor countries and Ukraine, regularity of financial assistance during and after the war, financial accountability and transparency.
INFORMATION SUPPORT FOR ACCOUNTING OF FINANCIAL RESULTS IN THE FOREST INDUSTRY
Authors:   Sumy National Agrarian University, Polyatykina Larysa
Published: July 2023

At the article the issue of the use of automated software that facilitates prompt response and control of the legality of operations were considered. The relevance of the study of the problem of accounting and automation of financial results by domestic forestry enterprises was confirmed. Different problems to increase and improve the efficiency of accounting of the financial results of the operation of enterprises in the forest industry were defined. In practice, this provides an opportunity to use automated software, facilitates prompt response and control of the legality of operations. It was justified that the automation process carried out will contribute to increasing the efficiency of the introduction of automation and their feasibility from an economic point of view, and also prevents their influence on the final result. Performing accounting of financial results under the conditions of an automated information processing system, the entire accounting process is carried out in several stages were installed. The characteristics of these stages were provided. The proposals when, with the help of modern software, accounting functions can be fully automated and the consequences of their work can be presented in any form convenient for users were justified. The introduction of automated accounting systems is a process, the result of which is an improvement in the quality of accounting data was considered. The result of the actions taken is the improvement of the management efficiency of the forest industry. It has been proven that the automated accounting system is appropriate when using it at forestry enterprises. Thanks to the introduction of automation, the time for processing various documents that do not require large storage spaces is reduced. As a result of the conducted research, recommendations were given to enterprises of the forestry industry to switch to the accounting information processing program BAS Accounting. The advantage of the efficiency of the resulting accounting information will be the strengthening of control over the legality and economic efficiency of business operations.
THE RELATIONSHIP BETWEEN INNOVATIVE AND SOCIAL-ETHICAL MARKETING AS A SOURCE OF COMPETITIVE ADVANTAGES
Authors:   Sumy National Agrarian University, Shumkova Olena , Shumkova Viktoriia ,   Sumy National Agrarian University, Kolodnenko Nataliia ,   Sumy National Agrarian University
Published: July 2023

The article examines the issue of using the concepts of innovative marketing and social-ethical marketing as related elements to increase the competitiveness of the enterprise. The purpose of the article is to study the possibility of combining the concepts of innovative marketing and socio-ethical marketing for the formation of sustainable competitive advantages of enterprises on domestic and global markets. The authors identified the main trends in consumer behavior in 2023 according to the report of the research company Euromonitor International and the possibility of using these trends for the implementation of innovative activities of the enterprise. It has been established that the needs of modern consumers are based on the principles of sustainable development and social responsibility. The main features of innovative marketing and socio-ethical marketing in terms of marketing complexes are established and synergistic connections between the two concepts are proposed. Also, as an idea for the development of the farm, the fragmentation of sown areas into ecological plots was proposed, where measures to improve the component qualities of products will be maximally observed. The authors proposed innovative steps of the company’s activity using the principles of social and ethical marketing. On the example of the farm company “Batkivshchyna” of the Krasnopilska community of the Sumy region, the possibility of combining the principles of innovative and socio-ethical marketing in its activities was considered. In the study, the authors proposed the production of pellets to improve the innovative and ecological indicators of the area of the Krasnopilska community and provide the population with energy resources for heating. The authors determined the amount of expenses for the farm to purchase equipment and the level of profitability of the activity of producing the pellets. It was determined that the introduction of innovation into the company’s activities will create certain positive social effects in the future, which will lead to the improvement of the economic condition of business and the development of the territorial community.
THE INFLUENCE OF INNOVATIVE BANKING TECHNOLOGIES ON THE IMPROVEMENT OF SERVICE TO CORPORATE CLIENTS
Authors:   Odessa National Economic University, Kretov Dmitry
Published: July 2023

In the changing conditions of life, it is very important to monitor the main trends in the development of banks. This contributes to the competent assessment of the activity of the banking system in the competitive market and the improvement of the quality of customer service, both retail and corporate. Constantly improving service delivery platforms reflect the result of hard work of specialists, increase the profitability of the banking sector and allow to maximize profits. The article deals with the implementation of financial innovations in the service of corporate clients by Ukrainian banks. It is emphasized that the catalyst for the development of digitization in banks was the quarantine conditions of 2020. The global trends in the development of innovations in banking practice have been studied. The best innovations in products and services for corporate clients are characterized. It was revealed that the main global banking innovations are: opening a digital account; application programming interfaces; video collaboration; p2p payments, cloud computing, chatbots, machine learning, digital lending systems. They ensure close communication between the bank and the client, quick receipt of products and services by clients, protection of bank data, and reduction of risks. Signs of attractiveness of new banking products are high reliability, profitability and quality, as well as profit from the introduction of modern financial technologies. The result of cooperation with fintech startups is new products and services or products and services with new qualities: innovative programs and projects; new intelligent products; modern new technological equipment and processes; new approaches to market formation of modern banking products and services. Particular attention is paid to ensuring the equality of the participants in the relationship (banks and clients) and the openness of the necessary information for them; provided own systematization of clients from the point of view of readiness for innovations and a list of the main innovative changes taking place in the banks’ service to corporate clients.
Initial growth and quality of jussara palm seedlings cultivated in biosolid-based substrates
Authors: Souza Antonio Maricélio Borges , Campos Thiago Souza , Ferreira Kássia Barros , Ferreira Nicoly Barros , Guedes Renata Bachin Mazzini , Pivetta Kathia Fernandes Lopes
Published: July 2023

All palms present ornamental appeal and may be widely used in landscaping, especially the native ones because of their ecological importance, such as the jussara palm (Euterpe edulis Mart.). In this sense, aiming at maximum plant development in the urban environment, it is necessary to use high-quality seedlings; the substrate is one of the key factors that directly influence it. The objective of this study was to evaluate the initial growth of jussara palm seedlings cultivated in biosolid-based substrates, which is a material of good characteristics besides attending sustainability issues. The experimental design was entirely randomized with six treatments consisted of substrates composed by biosolid (BIO) and subsoil (SS) at different proportions (v:v): 100% SS - control; 20% BIO + 80% SS; 40% BIO + 60% SS; 60% BIO + 40% SS; 80% BIO + 20% SS; 100% BIO. Seedlings were cultivated in a greenhouse and evaluated according to the following variables: height of aerial part; root length; collar diameter; leaf number; dry mass of aerial part and of roots; total dry mass; chlorophyll content; height of aerial part/collar diameter rate; dry mass of aerial part/dry mass of roots rate; and Dickson Quality Index. There was a significant effect (p < 0.05) for all evaluated characteristics. The biosolid, combined with subsoil, may be used for 20% and 40% substrate composition, as it is potentially appropriate for jussara palm seedling production. Higher proportions were toxic to seedling growth.
Eficacia de la expansión rápida maxilar en pacientes con apnea obstructiva del sueño. Revisión de literatura
Authors: Gualán Paladines Elian Alberto , Cabrera Padrón María Isabel
Published: July 2023

Introducción. La expansión rápida del maxilar es uno de los tratamientos indicados en los casos de constricción transversal del maxilar con el fin de mejorar aspectos funcionales y estéticos orofaciales. Objetivo. Efectuar una revisión de la literatura científica sobre la eficacia de la expansión rápida maxilar en pacientes con apnea obstructiva del sueño. Metodología. Se realizó una revisión literaria descriptiva y crítica a través de bases de datos digitales como: PubMed, Scielo y Google Academic. Se incluyeron artículos desde marzo del 2018 hasta febrero del 2023 publicados en los idiomas: portugués, inglés y español. Resultados. Se recopiló un total de 29 artículos y se analizó la eficacia de la expansión rápida maxilar como tratamiento para la apnea del sueño. Conclusión. Podemos concluir que la mayoría de estudios evaluados mencionan la existencia notable de un cambio positivo en el síndrome de apnea obstructivo del sueño tras la aplicación de tratamientos que expandan el hueso palatino como lo es la RME.
Híbridos de pimiento (Capsicum annuum L.)
Authors: Monge Perez José Eladio , Loría-Coto Michelle
Published: July 2023

Objetivos:  evaluar el rendimiento y la calidad de 11 híbridos de pimiento.  Metodología:  el ensayo se desarrolló en ambiente protegido, en Alajuela, Costa Rica.  Se empleó fibra de coco como sustrato para las plantas, y el suministro de nutrientes fue mediante fertirrigación.  Resultados:  se halló una importante variabilidad en los datos obtenidos por los híbridos para la edad al inicio de cosecha (75 – 82 días luego de trasplante), cantidad de frutos de calidad primera (5.29 – 14.84frutos/m2), peso del fruto de calidad primera (173.20 – 238.10g), y rendimiento comercial (4.41 – 7.62kg/m2) y total (5.63 – 8.97kg/m2).  Conclusiones:  Los híbridos con la mayor cantidad de frutos de calidad primera fueron SEO-13 y SKX-31 (14.84 y 14.15frutos/m2, respectivamente).  No hubo diferencias entre híbridos en el peso del fruto de calidad primera.  Los híbridos con el mayor rendimiento comercial fueron SKX-31 (7.62kg/m2) y SEO-15 (7.17kg/m2), y esos resultados son superiores a los encontrados con los híbridos SKX-39, SEO-11 y SKX-36.
On Quasi-para-Sasakian Structures on 5-dimensions
Authors: AKTAY Şirin , KOCABAŞ Ümmü
Published: July 2023

In this study, we investigate the existence of quasi-para-Sasakian structures on five dimensional nilpotent
Lie algebras. There are six non-abelian nilpotent Lie algebras. We show that quasi-para-Sasakian structures exist only on one of these algebras. Quasi-para-Sasakian structures correspond to the class G_5+G_8 in the classification of almost paracontact metric structures. We show that a quasi-para-Sasakian structure on a five dimensional nilpotent Lie algebra is either in G_5 or G_8.
Sumber Daya Proyek Konstruksi Patimban Port Development Project yang Mempengaruhi Kinerja Kontraktor
Authors: Rohmah Khoirina Putri Izza , Sugandi R. Machmud , Alfianto Imam
Published: July 2023

Construction project resources are one of the essential things in a construction phase. Every year, contractor performance decreases due to limitations in managing and managing project resources. One way contractors can deal with these problems is to improve quality performance during construction. One of the causes of problems at work is the resource factor. The resource factor in the construction process dramatically influences the contractor's performance. This study aims to analyze how much influence each factor of project resources (human resources, materials, equipment, implementation methods and information technology) of the project has Connecting Bridge, Patimban Port Development Project. The study collected sample data on 33 people involved in the project development process analysis using SEM-PLS analysis with the help of SmartPLS 3.0. From testing, this study's results indicate a positive and significant influence between the variables of human resources, materials, equipment amd implementation methods. This study's results obtained from the R square for the contractor performance variable were 0.809. It means that the percentage of human, material, equipment, implementation methods and information technology  resources is 80.9%, while other factors influence the remaining 19.1%.
Sifat Mekanik Bata Ringan Geopolimer Berdasarkan Rasio Si/AL
Authors: Rafrita Fasya Khoirianti , Anwar Siti Nur Rahmah , Umniati B. Sri
Published: July 2023

Pemanfaatan fly ash atau abu terbang masih minim diterapkan di Indonesia. Persentase pemanfaatan fly ash hanya 10-12% dengan 73% di Pulau Jawa dan 27% di pulau lainnya, maka akan terjadi penumpukan fly ash hingga 10,4 juta-ton per tahun pada tahun 2027. Fly ash yang melimpah dapat dimanfaatkan dengan menjadikan komposisi utama bata ringan sebagai pengganti semen yang disebut bata ringan geopolimer. Fly ash yang digunakan adalah kelas F dengan pengujian mekanik berdasarkan rasio Si/Al. Penelitian ini bertujuan untuk menganalisis pengaruh kadar aktivator terhadap pengujian mekanik yang terdiri dari kuat tekan, kuat tarik belah, dan modulus runtuh sehingga didapatkan sifat mekanik bata ringan geopolimer. Semakin tinggi kandungan kadar aktivator, menyebabkan rasio Si/Al semakin besar. Rasio pada kadar aktivator 35, 40, dan 45% adalah 2,42; 2,45; dan 2,48. Selisih antara kuat tarik belah terhadap kuat tekan untuk kadar aktivator 35% adalah 6,45%; 40% adalah 5,94%; dan 45% adalah 6,04% sehingga termasuk dalam bata ringan bermutu tinggi. Kadar aktivator berpengaruh secara signifikan terhadap kuat tekan, kuat tarik belah, dan modulus runtuh. Pada rasio Si/Al yang lebih rendah menyebabkan kuat tekan, kuat tarik belah, dan modulus runtuh yang didapatkan lebih tinggi dan lebih baik.
Studi Penanganan Jalan Amblas di Desa Sumbernanas, Kecamatan Gedangan, Kabupaten Malang
Authors: Sudjatmiko Eddy Triyanto , Siswanto Henri
Published: July 2023

Telah terjadi tanah longsor di dusun Sumbernanas Kecamatan Gedangan Kabupaten Malang. Peristiwa menyebabkan jalan amblas sepanjang 50 m pada ruas jalan Gedangan–Gondanglegi sedalam 3 m. Berbagai usaha telah dilakukan pengurugan pada lokasi tersebut, tetapi tidak menghasilkan kondisi yang diharapkan. Penelitian bertujuan untuk menganalisis penyebab jalan amblas dan menentukan metode penanganannya. Metode penelitian meliputi observasi lapangan, studi literatur geologi kawasan, pengukuran topografi, penyelidikan tanah in-situ, pengolahan data dan analisis, dan desain penanganan. Parameter desain ditentukan secara perhitungan-balik analisis kestablian lereng pada saat runtuh. Hasil analisis mengindikasikan bahwa jalan amblas disebabkan oleh kombinasi terikisnya bantaran alur sungai dan pelunakan tanah akibat dari infiltrasi aliran air bawah tanah. Desain penanganan yang diusulkan adalah pemasangan konstruksi gabion sebagai dinding penahan tanah. Perhitungan struktur menunjukan konstruksi yang diusulkan memberikan faktor keamanan FK > 1,5 untuk jangka pendek dan FK >1,1 pada saat gempa.
Divergencias sobre la Inocuidad del Paquete Tecnológico para la producción de Semillas Genéticamente Modificados
Authors: Walter Pablo Alberto
Published: July 2023

En América Latina y particularmente en Brasil y Argentina, el avance de los cultivares transgénicos se vio impulsado a partir de mediados de los años ’90. La velocidad de incorporación de esta tecnología, en los últimos años, se debió a que ésta acortaba el período de retorno de las inversiones. Este modelo productivo se impone en gran parte del mundo desde hace más de 20 años y se aplica bajo el paraguas del paradigma tecnológico de la modernización. Según algunos autores, el uso de este tecno-paquete, compuesto por la interacción de Semillas Transgénicas (ST) u Organismo Genéticamente Modificado (OGM), agroquímicos y siembra directa ha permitido aspectos positivos tales como disminuir la erosión de los suelos por la continua cobertura con residuos de cultivos y un ajustado control químico de las malezas. Por su parte, otros autores sostienen que el uso constante de este Paquete tecnológico produce efectos secundarios a largo plazo en el área de la salud humana, la salud animal y en la contaminación del espacio ambiental, afectando la diversidad biológica.
Este trabajo se realizó mediante la búsqueda de una exhaustiva revisión de material bibliográfico sobre esta temática, basado en información secundaria. Se observó que existe opiniones divergentes sobre la inocuidad y/o peligros del uso de este Paquete Tecnológico en la salud humana y en el medio ambiente por su uso y la acción de sus componentes en todo el proceso agropecuario y/o destino alimenticio.
Healthcare professionals' satisfaction toward the use of district health information system and its associated factors in southwest Ethiopia: using the information system success model
Authors: Walle Agmasie Damtew , Demsash Addisalem Workie , Ferede Tigist Andargie , Wubante Sisay Maru
Published: July 2023

Background

Ethiopia has the potential to use the district health information system, which is a building block of the health system. Thus, it needs to assess the performance level of the system by identifying the satisfaction of end users. There is little evidence about users' satisfaction with using this system. As a result, this study was conducted to fill this gap by evaluating user satisfaction and associated factors of district health information system among healthcare providers in Ethiopia, using the information system success model.

Methods

An institutional-based cross-sectional study was conducted from November to December 2022 in the Oromia region of southwest Ethiopia. A total of 391 health professionals participated in the study. The study participants were selected using a census. Using a self-administered questionnaire, data were collected. Measurement and structural equation modeling analyses were used to evaluate reliability, the validity of model fit, and to test the relationship between the constructs, respectively, using analysis of moment structure (AMOS) V 26.

Results

System quality had a positive direct effect on the respondent's system use (β = 0.18, P-value < 0.001), and satisfaction (β = 0.44, P-value < 0.001). Service quality had also a direct effect on the respondent's system use (β = 0.37, P-value < 0.01), and satisfaction with using the district health information system (β = 0.36, P-value < 0.01). Similarly, system use had also a direct effect on the respondent's satisfaction (β = 0.53, P-value < 0.05). Moreover, computer literacy had a direct effect on the respondent's system use (β = 0.63, P-value < 0.05), and satisfaction (β = 0.51, P-value < 0.01).

Concussions

The overall user satisfaction with using the district health information system in Ethiopia was low. System quality, service quality, and computer literacy had a direct positive effect on system use and user satisfaction. In addition, system use and information quality had a direct positive effect on healthcare professionals' satisfaction with using the district health information system. The most important factor for enhancing system use and user satisfaction was computer literacy. Accordingly, for the specific user training required for the success of the district health information system in Ethiopia, the manager should offer additional basic computer courses for better use of the system.
Responses of economic and anatomical leaf traits to soil fertility factors in eight coexisting broadleaf species in temperate forests
Authors: Jin Mingyue , Jin Guangze , Guo Qingxi , Liu Zhili
Published: July 2023

The multidimensionality of leaf traits allows plants to have diverse survival strategies to adapt to complex living environments. Whether the anatomical traits of leaves are associated with leaf economic traits and which group of traits are more strongly correlated with soil fertility factors remains unclear. We measured four leaf economic traits, four anatomical traits, and five soil fertility factors of eight coexisting broadleaf species distributed in mixed broadleaved-Korean pine (Pinus koraiensis) forests located in Northeast China. Results show a strong interdependence between economic and anatomical traits (p < 0.05). The range of variation between economic and anatomical traits were almost equal, but the causes of variation were different. Specific leaf area was positively correlated with the abaxial epidermis, negatively correlated with the ratio of spongy tissue to leaf thickness (ST/LT), and not correlated with adaxial epidermis. Leaf dry matter content was negatively correlated with the abaxial epidermis and adaxial epidermis, positively correlated with ST/LT. Specific leaf area, palisade tissue, and ST/LT showed stronger correlation with soil fertility factors than other traits. Soil fertility factors dominating trait variation were dependent upon the trait. Our results suggest anatomical traits can be considered in economic trait dimension. The coupled relationship between anatomical and economic traits is potentially a cost-effective adaptation strategy for species to improve efficiency in resource utilization. Our results provide evidence for the complex soil-trait relationship and suggest that future studies should emphasize the role of anatomic traits in predicting soil fertility changes.
Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression
Authors: Rafaeva Maria , Jensen Adina R. D. , Horton Edward R. , Zornhagen Kamilla W. , Strøbech Jan E. , Fleischhauer Lutz , Mayorca-Guiliani Alejandro E. , Nielsen Sebastian R. , Grønseth Dina S. , Kuś Filip , Schoof Erwin M. , Arnes Luis , Koch Manuel , Clausen-Schaumann Hauke , Izzi Valerio , Reuten Raphael , Erler Janine T.
Published: July 2023

The desmoplastic reaction observed in many cancers is a hallmark of disease progression and prognosis, particularly in breast and pancreatic cancer. Stromal-derived extracellular matrix (ECM) is significantly altered in desmoplasia, and as such plays a critical role in driving cancer progression. Using fibroblast-derived matrices (FDMs), we show that cancer cells have increased growth on cancer associated FDMs, when compared to FDMs derived from non-malignant tissue (normal) fibroblasts. We assess the changes in ECM characteristics from normal to cancer-associated stroma at the primary tumor site. Compositional, structural, and mechanical analyses reveal significant differences, with an increase in abundance of core ECM proteins, coupled with an increase in stiffness and density in cancer-associated FDMs. From compositional changes of FDM, we derived a 36-ECM protein signature, which we show matches in large part with the changes in pancreatic ductal adenocarcinoma (PDAC) tumor and metastases progression. Additionally, this signature also matches at the transcriptomic level in multiple cancer types in patients, prognostic of their survival. Together, our results show relevance of FDMs for cancer modelling and identification of desmoplastic ECM components for further mechanistic studies.
Oxidative conditions along the continental shelf of the Southeast Pacific during the last two millennia: a multiproxy interpretation of the oxygen minimum zone variability from sedimentary records
Authors: Muñoz Praxedes , Castillo Alexis , Valdés Jorge , Dewitte Boris
Published: July 2023

The oxygen minimum zone (OMZ) is an essential feature along the Pacific margin, extensively studied for its influence on benthic fauna, acquiring relevance in coastal zones due to its impact on aquaculture species, marine-managed areas, and marine-protected areas. The most evident temporal variability beyond seasonal timescales observed for the OMZ was related to inter-annual variability associated with El Niño, when warmer and more oxygenated waters arrive at shallower zones and the OMZ becomes deeper. However, the impact of oxygen-deficient water that appears sporadically over the shelf is not yet understood. This study provides an integrated view of the oceanographic and climatic conditions behind bottom oxygen conditions along the Chilean continental margin, considering the temporal variability in the South East (SE) Pacific during the last ~2000 years. We organized the information on redox-sensitive metals and δ15N from sedimentary cores obtained from shelf zones from 23°S to 36°S at water depths lower than 100 m. The results demonstrate the variability in the upper part of the OMZ over the shelf, which seems to respond to climatic oscillations. The element distribution indicated in particular a more intense OMZ was developed over the shelf before 1400 AD, followed by more oxygenated bottom conditions afterward, except between 1925 and 1970 off 36°S when the OMZ was intensified, a condition that was not observed at the northern sites. This period mostly coincided with a low Pacific Decadal Oscillation amplitude and reduced El Niño Southern Oscillation (ENSO) activity. In the last 50 years, the proxy data suggests less intense suboxic environment along the Chilean margin. This weakening of the upper boundary of the OMZ in the last decades is interpreted as resulting from the accumulative effect of ventilation processes at different time scales.
GOLD stage-specific phenotyping of emphysema and airway disease using quantitative computed tomography
Authors: Konietzke Philip , Brunner Christian , Konietzke Marilisa , Wagner Willi Linus , Weinheimer Oliver , Heußel Claus Peter , Herth Felix J. F. , Trudzinski Franziska , Kauczor Hans-Ulrich , Wielpütz Mark Oliver
Published: July 2023

Background

In chronic obstructive pulmonary disease (COPD) abnormal lung function is related to emphysema and airway obstruction, but their relative contribution in each GOLD-stage is not fully understood. In this study, we used quantitative computed tomography (QCT) parameters for phenotyping of emphysema and airway abnormalities, and to investigate the relative contribution of QCT emphysema and airway parameters to airflow limitation specifically in each GOLD stage.

Methods

Non-contrast computed tomography (CT) of 492 patients with COPD former GOLD 0 COPD and COPD stages GOLD 1–4 were evaluated using fully automated software for quantitative CT. Total lung volume (TLV), emphysema index (EI), mean lung density (MLD), and airway wall thickness (WT), total diameter (TD), lumen area (LA), and wall percentage (WP) were calculated for the entire lung, as well as for all lung lobes separately. Results from the 3rd-8th airway generation were aggregated (WT3-8, TD3-8, LA3-8, WP3-8). All subjects underwent whole-body plethysmography (FEV1%pred, VC, RV, TLC).

Results

EI was higher with increasing GOLD stages with 1.0 ± 1.8% in GOLD 0, 4.5 ± 9.9% in GOLD 1, 19.4 ± 15.8% in GOLD 2, 32.7 ± 13.4% in GOLD 3 and 41.4 ± 10.0% in GOLD 4 subjects (p < 0.001). WP3-8 showed no essential differences between GOLD 0 and GOLD 1, tended to be higher in GOLD 2 with 52.4 ± 7.2%, and was lower in GOLD 4 with 50.6 ± 5.9% (p = 0.010 – p = 0.960). In the upper lobes WP3–8 showed no significant differences between the GOLD stages (p = 0.824), while in the lower lobes the lowest WP3-8 was found in GOLD 0/1 with 49.9 ± 6.5%, while higher values were detected in GOLD 2 with 51.9 ± 6.4% and in GOLD 3/4 with 51.0 ± 6.0% (p < 0.05). In a multilinear regression analysis, the dependent variable FEV1%pred can be predicted by a combination of both the independent variables EI (p < 0.001) and WP3–8 (p < 0.001).

Conclusion

QCT parameters showed a significant increase of emphysema from GOLD 0–4 COPD. Airway changes showed a different spatial pattern with higher values of relative wall thickness in the lower lobes until GOLD 2 and subsequent lower values in GOLD3/4, whereas there were no significant differences in the upper lobes. Both, EI and WP5-8 are independently correlated with lung function decline.