bluuebunny/crossref_metadata_2025 huggingface dataset:
Birth defects in infants born to employees of a microelectronics and business machine manufacturing facility
Authors: Silver Sharon R. , Pinkerton Lynne E. , Rocheleau Carissa M. , Deddens James A. , Michalski Adrian M. , Van Zutphen Alissa R.
Published: May 2016

Background

Concerns about solvent releases from a microelectronics/business machine manufacturing facility in upstate New York led to interest in the health of former workers, including this investigation of birth defects in children of male and female employees.

Methods

Children born 1983 to 2001 to facility employees were enumerated and matched to New York State's Congenital Malformations Registry. Reported structural birth defects were compared with numbers expected from state rates (excluding New York City), generating standardized prevalence ratios (SPRs). Exposure assessors classified employees as ever/never potentially exposed at the facility to metals, chlorinated hydrocarbons, and other hydrocarbons during windows critical to organogenesis (female workers) or spermatogenesis (male workers). Among workers, adjusted prevalence ratios were generated to evaluate associations between potential exposures and specific birth defects.

Results

External comparisons for structural defects were at expectation for infants of male workers (SPR = 1.01; 95% confidence interval [CI], 0.77–1.29; n = 60) and lower for births to female workers (SPR = 0.84; 95% CI, 0.50–1.33; n = 18). Among full‐term infants of male workers, ventricular septal defects (VSDs) were somewhat elevated compared with the general population (SPR = 1.58; 95% CI, 0.99–2.39; n = 22). Within the cohort, potential paternal metal exposure was associated with increased VSD risk (adjusted prevalence ratio = 2.70; 95% CI, = 1.09–6.67; n = 7).

Conclusion

While overall SPRs were near expectation, paternal exposure to metals (primarily lead) appeared to be associated with increased VSD risk in infants. Take‐home of occupational exposures, nonoccupational exposures, and chance could not be ruled out as causes. Case numbers for many defects were small, limiting assessment of the role of occupational exposures. Birth Defects Research (Part A) 106:696–707, 2016. © 2016 Wiley Periodicals, Inc.
Bayesian analysis of censored response data in family‐based genetic association studies
Authors: Del Greco M. Fabiola , Pattaro Cristian , Minelli Cosetta , Thompson John R.
Published: May 2016

Biomarkers are subject to censoring whenever some measurements are not quantifiable given a laboratory detection limit. Methods for handling censoring have received less attention in genetic epidemiology, and censored data are still often replaced with a fixed value. We compared different strategies for handling a left‐censored continuous biomarker in a family‐based study, where the biomarker is tested for association with a genetic variant, , adjusting for a covariate, X. Allowing different correlations between X and , we compared simple substitution of censored observations with the detection limit followed by a linear mixed effect model (LMM), Bayesian model with noninformative priors, Tobit model with robust standard errors, the multiple imputation (MI) with and without in the imputation followed by a LMM. Our comparison was based on real and simulated data in which 20% and 40% censoring were artificially induced. The complete data were also analyzed with a LMM. In the MICROS study, the Bayesian model gave results closer to those obtained with the complete data. In the simulations, simple substitution was always the most biased method, the Tobit approach gave the least biased estimates at all censoring levels and correlation values, the Bayesian model and both MI approaches gave slightly biased estimates but smaller root mean square errors. On the basis of these results the Bayesian approach is highly recommended for candidate gene studies; however, the computationally simpler Tobit and the MI without are both good options for genome‐wide studies.
The Use of NMR Metabolite Profiling and in vivo Hypoglycemic Assay for Comparison of Unfractionated Aqueous Leaf Extracts of Two Ocimum Species
Authors: Casanova Livia Marques , Espíndola‐Netto Jair Machado , Tinoco Luzineide Wanderley , Sola‐Penna Mauro , Costa Sônia Soares
Published: May 2016

Ocimum basilicum and Ocimum gratissimum (Lamiaceae) are used to treat diabetes mellitus in Africa. In a previous work, we identified chicoric acid as a hypoglycemic substance in O. gratissimum. This study aims to compare the chemical metabolite profile and the hypoglycemic activity of unfractionated aqueous extracts from leaves of both Lamiaceae species. The metabolite composition of OB and OG decoctions (10% w/v) was analyzed using HPLC‐DAD and NMR tools. Chicoric acid showed to be the major phenolic in both extracts, besides caftaric, caffeic, and rosmarinic acids; nevertheless, there is approximately three times more of this substance in OG. From 1D‐ and 2D‐NMR analyses, 19 substances were identified in OB, while 12 in OG. The in vivo acute hypoglycemic activity of the extracts was assessed intraperitoneally in streptozotocin (STZ)‐induced diabetic mice. The doses of 100 and 200 mg/kg of both extracts significantly reduced their glycemia, compared to controls (P < 0.05). OB was a little more effective than OG, despite the lower content of chicoric acid in OB. This result strongly suggests that components other than chicoric acid contribute to the hypoglycemic activity of the two extracts. Despite the abundance of caffeic and rosmarinic acids in OB, their hypoglycemic activity observed at 8.3 μmol/kg was low. This is the first chemical profile of crude extracts from Ocimum species by NMR. Our findings confirmed the potential of both species in DM treatment in spite of marked differences in their chemical composition. However, long‐term studies are necessary in order to identify the most promising of the two species for the development of an herbal medicine.
Geographic Distribution of Natural Products Produced by the Red Alga Laurencia dendroidea J. Agardh
Authors: Machado Fernanda L. S. , Duarte Heitor M. , Gestinari Lísia M. S. , Cassano Valéria , Kaiser Carlos R. , Soares Angélica R.
Published: May 2016

In order to evaluate the chemical diversity of Laurencia dendroidea J. Agardh, a widely distributed seaweed in Brazilian coast, a phytochemical study was carried out with algae collected from six different locations along the Southeast Brazilian coast. Purified compounds were identified by MS and NMR techniques. The chemical profiles of lipophilic extracts were obtained by GC/MS for each population. In total, 15 compounds were described. The sesquiterpene composition accounted for 49 – 63% of the GC/MS chromatogram area. The discrimination of three chemotypes was done by the use of HCA on GC/MS chromatograms. They were also analyzed by the PCA and, together with peak area analysis, it was possible to discriminate all populations by the main variation of elatol, obtusol, rogiolol, and triquinane. The results revealed the high diversity of sesquiterpene composition among populations of L. dendroidea. Curiously, the within and among population variation of elatol and obtusol suggested a biochemical interplay on the content of these compounds. More studies are necessary to understand the patterns of chemical diversity and compound variation within and among populations of L. dendroidea.
Hydrophilic trans‐Cyclooctenylated Noncanonical Amino Acids for Fast Intracellular Protein Labeling
Authors: Kozma Eszter , Nikić Ivana , Varga Balázs R. , Aramburu Iker Valle , Kang Jun Hee , Fackler Oliver T. , Lemke Edward A. , Kele Péter
Published: May 2016

Introduction of bioorthogonal functionalities (e.g., trans‐cyclooctene‐TCO) into a protein of interest by site‐specific genetic encoding of non‐canonical amino acids (ncAAs) creates uniquely targetable platforms for fluorescent labeling schemes in combination with tetrazine‐functionalized dyes. However, fluorescent labeling of an intracellular protein is usually compromised by high background, arising from the hydrophobicity of ncAAs; this is typically compensated for by hours‐long washout to remove excess ncAAs from the cellular interior. To overcome these problems, we designed, synthesized, and tested new, hydrophilic TCO‐ncAAs. One derivative, DOTCO‐lysine was genetically incorporated into proteins with good yield. The increased hydrophilicity shortened the excess ncAA washout time from hours to minutes, thus permitting rapid labeling and subsequent fluorescence microscopy.
Solution Structure of Turbo‐Hauser Base TMPMgCl⋅LiCl in [D8]THF
Authors: Neufeld Roman , Stalke Dietmar
Published: May 2016

Turbo‐Hauser bases are very useful and highly reactive organometallic reagents in synthesis. Especially TMPMgCl⋅LiCl 1 (TMP=2,2,6,6‐tetramethylpiperidide) is an excellent base for converting a wide range of (hetero)aromatic substrates into highly functionalized compounds with a broad application in organic synthesis. The knowledge of its structure in solution is of essential importance to understand the extraordinary reactivity and selectivity. However, very little is known about the aggregation of this prominent reagent in solution. Herein, we present the THF‐solution structure of 1 by employing our newly elaborated DOSY NMR method based on external calibration curves (ECC) with normalized diffusion coefficients.
Turn‐On Fluorogenic and Chromogenic Detection of Small Aromatic Hydrocarbon Vapors by a Porous Supramolecular Host
Authors: Hatanaka Sou , Ono Toshikazu , Hisaeda Yoshiio
Published: May 2016

Benzene, toluene, ethylbenzene, the isomers of xylene, and trimethylbenzene are harmful volatile organic compounds and pose risks to human health and the environment. However, there are currently no effective chemosensors for vapors of these compounds. A porous supramolecular host for turn‐on fluorogenic and chromogenic detection of the vapors of small aromatic hydrocarbons is presented. The host was constructed from a naphthalenediimide derivative that was supramolecularly connected to tris(pentafluorophenyl)borane. The amorphous powder form of the host allowed for effective accommodation of vapors of small aromatic hydrocarbons, resulting in a guest‐dependent fluorescence emission. Increases in the fluorescence yield of 76‐, 46‐, and 37‐fold were observed with toluene, benzene, and m‐xylene, respectively. Negligible responses were obtained with common organic solvents. This simple supramolecular host could be applied as a useful sensor of small aromatic hydrocarbon vapors.
Structural Basis for Bulky‐Adduct DNA‐Lesion Recognition by the Nucleotide Excision Repair Protein Rad14
Authors: Simon Nina , Ebert Charlotte , Schneider Sabine
Published: May 2016

Heterocyclic aromatic amines react with purine bases and result in bulky DNA adducts that cause mutations. Such structurally diverse lesions are substrates for the nucleotide excision repair (NER). It is thought that the NER machinery recognises and verifies distorted DNA conformations, also involving the xeroderma pigmentosum group A and C proteins (XPA, XPC) that act as a scaffold between the DNA substrate and several other NER proteins. Here we present the synthesis of DNA molecules containing the polycyclic, aromatic amine C8‐guanine lesions acetylaminophenyl, acetylaminonaphthyl, acetylaminoanthryl, and acetylaminopyrenyl, as well as their crystal structures in complex with the yeast XPA homologue Rad14. This work further substantiates the indirect lesion‐detection mechanism employed by the NER system that recognises destabilised and deformable DNA structures.
ChemInform Abstract: Aurivillius Phases, a Novel Class of Metal Oxide Superconductors?
Authors: YEE K. A. , ALBRIGHT T. A. , JUNG D. , WHANGBO M.‐H.
Published: May 2016

Tight binding calculations performed for (Bi2O2)2NbO4, BiNb2O7, and Bi3Nb4O13 indicate that the electronic structure of Aurivillius phases characterized by layered perovskite‐blocks containing metal atoms with nearly d3‐configuration is very similar to the structure of the Cu‐O high Tc superconductors.
ChemInform Abstract: PbMo5O8 (I) and Tl0.8Sn0.6Mo7O11 (II), New Clusters of Molybdenum and Thallium.
Authors: DRONSKOWSKI R. , SIMON A.
Published: May 2016

The title compounds are prepared by annealing pressed pellets of stoichiometric mixtures of Mo, MoO2, and Pb (Tl and Sn, resp.) at 1200‐1300 °C (7 d, evacuated quartz ampoule, ∼100% yield).
ChemInform Abstract: Relaxation Mechanism of Germanium‐73 in Tetrabromogermane and Tetraiodogermane at High Temperature
Authors: HARAZONO T. , TANAKA K. , TAKEUCHI Y.
Published: May 2016

(25‐105 °C).
ChemInform Abstract: A Study of the Underpotential Deposition of Copper onto Polycrystalline Palladium Surfaces
Authors: SZABO S. , BAKOS I. , NAGY F. , MALLAT T.
Published: May 2016

(palladized Pt electrode) show that traces of Cl‐ and adsorbed Cu atoms, forming some kind of catalyst on the Pd surface, accelerate Pd corrosion during Cu desorption.
ChemInform Abstract: Gas‐Phase Photoinduced Reactivity of Co2NO+ with O2 via a Photoisomerization Mechanism.
Authors: GORD J. R. , FREISER B. S.
Published: May 2016

Previously, two forms of Co2NO+ have been identified, one which reacts with 18O2 to yield Co218O2 and NO, and a second one which does not react with 18O2.
ChemInform Abstract: Preparation of Silicon Arsenides by Using Chemical Transport Reactions.
Authors: UGAI YA. A. , GONCHAROV E. G. , ZAVRAZHNOV A. YU. , POPOV A. E. , VAVRESYUK I. V.
Published: May 2016

Mixtures of As, AsI3 and Si (or SiAs) are heated in evacuated quartz ampoules.
ChemInform Abstract: Growth of Wulfenite Crystals by the Flux Method.
Authors: OISHI S. , HIRAO M.
Published: May 2016

Wulfenite (PbMoO4) crystals are grown at temp. ≤ 600°C from LiCl‐NaCl, NaCl‐KCl, or KCl‐LiCl fluxes containing PbO and MoO3.
ChemInform Abstract: Metal Ion Specificity of “Zinc Finger” Proteins.
Authors: BERG J. M. , MERKLE D. L.
Published: May 2016

Quantitative metal binding studies of the peptide (I) are carried out.
ChemInform Abstract: Nitrilimine and Nitrile Oxide Cycloaddition to cis‐Condensed 1,3‐Dihydrooxazines.
Authors: STAJER G. , BERNATH G. , SZABO A. E. , SOHAR P. , ARGAY G. , KALMAN A.
Published: May 2016

The fused tetrahydro‐1,3‐oxazines (I) or (IV) undergo 1,3‐dipolar cycloaddition reaction with benzonitrile oxide or diphenylnitrilimine, both generated in situ, yielding selectively the fused oxadiazoles (III) or triazoles (VI).
ChemInform Abstract: A 3‐Methylene‐1,2‐dioxetane (II) as a Possible Chemiluminescent Intermediate in Singlet Oxygenation of Allene
Authors: AKASAKA T. , FUKUOKA K. , ANDO W.
Published: May 2016

Photosensitized oxygenation of (I) at ‐78 °C affords adamantanone (III).
ChemInform Abstract: Considered Novel Aromatic Systems. Part 10. Methylated Biphenylene Dianions: NMR Spectroscopic and Theoretical Investigation.
Authors: BAUSCH J. W. , GREGORY P. S. , OLAH G. A. , PRAKASH G. K. S. , VON RAGUE SCHLEYER P. , SEGAL G. A.
Published: May 2016

A range of methyl biphenylenes such as (I) react with Li in THF (as well as 2‐MeTHF in some cases).
ChemInform Abstract: Addition of Aliphatic and Aromatic Amines to Catechol in Aqueous Solution Under Oxidizing Conditions.
Authors: MANTHEY M. K. , PYNE S. G. , TRUSCOTT R. J. W.
Published: May 2016

The oxidation products in aqueous solution, enzyme‐catalyzed at physiological pH or under alkaline conditions, are dependent on the type of amine used.
ChemInform Abstract: Mechanism of Thiophene Hydrodesulfuration: Conversion of 2,3‐ and 2,5‐Dihydrothiophene and Model Organometallic Compounds.
Authors: SAUER N. N. , MARKEL E. J. , SCHRADER G. L. , ANGELICI R. J.
Published: May 2016

It is suggested that desulfuration of (I) occurs by isomerization to give butadiene (III) via (II).
ChemInform Abstract: An Unprecedented Intramolecular Migration of Carbon Groups from Aluminum to an Adjacent Vinylic Center and Its Application to the Synthesis of Stereodefined Olefins.
Authors: MILLER J. A.
Published: May 2016

The title reaction starts with the addition of the chloroalkyne (I) to freshly prepared sodium trimethylaluminate (II), yielding the cis‐adduct (III) which is not isolated, but undergoes base‐induced migration of the aluminum moiety to form the trans‐derivative (IV).
ChemInform Abstract: Synthesis of Tertiary Alcohol Carbamates.
Authors: NIKIFOROV A. , JIROVETZ L. , BUCHBAUER G.
Published: May 2016

The tertiary alcohols (II) are converted to their lithium alkoxides by reacting them with BuLi.
ChemInform Abstract: 2,5‐Dihydroxythiophene.
Authors: CAPON B. , WU Z.‐P.
Published: May 2016

Careful acid‐induced desilylation of the bis(siloxy)thiophene (I) yields the desired 2,5‐dihydroxythiophene (II) which tautomerizes to give the dione (III).
ChemInform Abstract: Polycarbonyl Heterocycles. Part 4. Knoevenagel Reaction of Thiazolidine‐4,5‐dione Derivatives.
Authors: ZALESKA B.
Published: May 2016

The reaction of the title compounds such as (I) with malonodinitrile proceeds without a catalyst and results in formation of (III).
ChemInform Abstract: Heterocyclic Systems Containing Chroman Moiety as Potential Antifungal and Antibacterial Agents: Synthesis of Mercaptotriazoles, Mercaptooxadiazoles and Hydrazide N‐Benzylidene Derivatives.
Authors: AHLUWALIA V. K. , MANN R. R. , BALA S.
Published: May 2016

Sixteen mercaptotriazoles of type (VI), the mercaptooxadiazoles (VIII) and ten hydrazide N‐benzylidene derivatives of type (X) are prepared via the common intermediates (IV).
ChemInform Abstract: Studies on the Stability of 2,2,4‐Trialkyl‐2,3‐dihydro‐1H‐(1,4)diazepino(2,3‐f)quinolines.
Authors: REDDY A. P. , VEERANAGAIAH V.
Published: May 2016

On treatment with acid or under thermal conditions (dry pyrolysis; refluxing in decalin or diphenyl ether), the title compounds (I) form exclusively the products (II) (discussion of the formation mechanism).
ChemInform Abstract: Chemotherapeutic Agents. Part 13. Synthesis of 2‐Pyridyl‐1,2,4‐triazolo(1,5‐a)pyrimidines as Antimicrobial Agent.
Authors: RAM V. J. , KUSHWAHA D. S. , MISHRA L.
Published: May 2016

A series of 1,2,4‐triazolo(1,5‐a)pyrimidine derivatives are prepared from the triazoles (I) as is shown for some reactions starting from (Ia) (all yields given in g).
ChemInform Abstract: Synthesis and Cation‐Binding Abilities of Novel Polyquinane Crown Ethers (III) Containing a Bis‐Acetal Ether Functionality.
Authors: MEHTA G. , RAO K. S. , KRISHNAMURTHY N. , SRINIVAS V. , BALASUBRAMANIAN D.
Published: May 2016

Complexation characteristics and ability of the host molecules (III) to translocate cations across phospholipid bilayer vesicles of liposomes are studied.
ChemInform Abstract: α‐Keto Phosphonoacetates.
Authors: MCKENNA C. E. , LEVY J. N.
Published: May 2016

Thermal decomposition of the diazophosphonoacetate (I) in the presence of propylene oxide and rhodium acetate gives the α‐keto ester (III) which reacts with water or primary alcohols, e.g. methanol (IIIb), forming the hemiacetals (IV).
ChemInform Abstract: Competitive Nucleophilic Aromatic Substitution and Haloarene Reduction in the Synthesis of Bimetallic π‐Arene Complexes: The Structural Characterization of (Et4N) ((η6‐((CO)5W)C6H5)Cr(CO)3).
Authors: HEPPERT J. A. , THOMAS‐MILLER M. E. , SCHERUBEL D. M. , TAKUSAGAWA F. , MORGENSTERN M. A. , SHAKER M. R.
Published: May 2016

The chloroarene complex (Ia) reacts with the carbonylferrate (II) to give (III), whereas analogous complexes (V) are prepared starting with (Ib).
ChemInform Abstract: High‐Yield Synthesis of Mo(η6‐PhPMe2)(PMe2Ph)3 and Its Dimerization to Form (Mo(.mu±eta.1,η6‐PMe2Ph)(PMe2Ph)2)2, a Complex Characterized by X‐Ray Crystallography.
Authors: COTTON F. A. , LUCK R. L. , MORRIS R. H.
Published: May 2016

The reduction of Mo2Cl10 (I) with iodine‐activated Mg in the presence of the phosphine (II) yields the monomeric title complex (III).
ChemInform Abstract: Synthesis of (Alkenyl(dimethylamino)carbene)tungsten Complexes Using the Peterson Reaction: X‐Ray Crystal Structure of (E)‐(CO)5W(C(NMe2)CH=CH(η‐C5H4)Fe(η‐C5H5)).
Authors: MACOMBER D. W. , MADHUKAR P. , ROGERS R. D.
Published: May 2016

Treatment of (III) with BuLi yields a lithium salt which reacts with several nonenolizable aldehydes or ketones to yield the desired title complexes such as (V), exclusive formation of the E isomer occurs.
ChemInform Abstract: Dihydrodiborolyl‐Transition Metal‐Carboranyl Triple‐Decker Sandwich Complexes.
Authors: ATTWOOD M. D. , FONDA K. K. , GRIMES R. N. , BRODT G. , HU D. , ZENNECK U. , SIEBERT W.
Published: May 2016

Thermal displacement of the cyclooctatriene ligand in (I) by the neutral complex (II) affords the air‐sensitive, paramagnetic triple‐decker sandwich compounds (III), the first designed complexes incorporating boron heterocycles and carborane ligands face‐bound to common metal centers.
ChemInform Abstract: Selective Rhodium‐Catalyzed Hydroformylation with the Tri‐ and Tetraphosphine Ligands (CH3)1,0Si(CH2CH2PPh2)3,4. Formation of Rh(Si(CH2CH2PPh2)3)(CO) via CH3‐Si Bond Cleavage and Structure of This Rh(I)‐Si Bonded Complex.
Authors: HENDRIKSEN D. E. , OSWALD A. A. , ANSELL G. B. , LETA S. , KASTRUP R. V.
Published: May 2016

The flexible, nonchelating phosphine ligands (III) are prepared and used in th Rh‐catalyzed hydroformylation of 1‐butene (IV) to yield unusually high selectivity to the linear aldehyde product (VII) at low (III)/Rh ratios of 3‐4. During continuous hydroformylation with the ligand (IIIa), the inactive title complex (VIII) is formed.
ChemInform Abstract: Functionally Substituted Vinyl Carbanions. Part 38. C‐Glucosides by Direct 1‐C‐Lithiation of 2‐Phenylsulfinyl‐Activated D‐Glucal.
Authors: PREUSS R. , SCHMIDT R. R.
Published: May 2016

Lithiation of the diastereomeric sulfoxides (I) (of uncertain assignment) and subsequent treatment with either propionaldehyde (II) or the arabinose derivative (V) yields the epimers (III)/(IV) and (VI)/(VII).
ChemInform Abstract: A Mild Procedure for the Preparation of 1,6‐Anhydro‐β‐D‐hexopyranoses and Derivatives.
Authors: LAFONT D. , BOULLANGER P. , CADAS O. , DESCOTES G.
Published: May 2016

The title compounds (II) are obtained by treatment of 6‐O‐tosyl‐D‐hexopyranoses (I) with DBU.
ChemInform Abstract: Formation of 2,6‐Bis(4′‐hydroxy‐3′‐methoxyphenyl)‐3,7‐dioxabicyclo(3.3.0)octa‐1,5‐diene by Phenolic Oxidation of Pinoresinol, a Furofuranoid Lignan.
Authors: JACK I. R. , WARD R. S. , PELTER A.
Published: May 2016

In order to investigate the reaction pathways in the formation of furofuranoid lignans, the phenolic oxidation of pinoresinol (Ia) is studied.
ChemInform Abstract: Chiral Synthesis of (+)‐Methyl 5‐epi‐Shikimate by Asymmetric Diels‐Alder Reaction of (S)S‐3‐(2‐Pyridylsulfinyl)acrylate.
Authors: TAKAHASHI T. , IYOBE A. , ARAI Y. , KOIZUMI T.
Published: May 2016

The known asymmetric Diels‐Alder reaction of the chiral acrylate (II) with furan (I) is one key step in the synthesis of (+)‐methyl 5‐epishikimate (XII).
ChemInform Abstract: Chemistry of Cyclic Phosphorus Compounds. Part 3. Synthesis of Pheromones Having an γ,δ‐Unsaturated Ketone System from 1,1‐Diphenylphospholanium Perchlorate.
Authors: YAMAMOTO I. , TANAKA S. , FUJIMOTO T. , OHTA K.
Published: May 2016

The cyclic phosphonium salt (I) is employed in the olefination of hexanal (II), yielding the ω‐phosphinoylalkene (III).
ChemInform Abstract: A Magnetism and X‐Ray Photoelectron Spectroscopic Study on FeMoO4Cl and LiFeMoO4Cl
Authors: CHOY J.‐H. , NOH D.‐Y. , SON K. ‐A , SEUNG D.‐Y.
Published: May 2016

is performed to analyze the elements participating in the redox reaction and to understand the nature of intra‐ and interlayer bonding before and after Li intercalation into the FeMoO4Cl host lattice.
ChemInform Abstract: Kinetic and Mechanistic Investigations of F + H2O/D2O and F + H2/D2 over the Temperature Range 240‐373 K.
Authors: STEVENS P. S. , BRUNE W. H. , ANDERSON J. G.
Published: May 2016

The rate constants of the title reactions are determined to be 1.6·10‐11 exp(‐28/T)cm3molecule‐1s‐1and 8.4·10‐12 exp(‐260/T)cm3molecule‐1s‐1for the reactions of F with H2O and D2O, resp., and 1.2·10‐10 exp(‐470/T)cm3molecule‐1s‐1and 9.3·10‐11 exp(‐680/T)cm3molecule‐1s‐1for the reactions with H2 and D2.
ChemInform Abstract: Use of α‐Anilinodienenitriles as Nucleophiles in Cycloadditions.
Authors: FANG J.‐M. , YANG C.‐C. , WANG Y.‐W.
Published: May 2016

The α‐anilinodienenitriles (III) are prepared by two methods, either via Peterson reaction of the α‐anilinoacetonitriles (I) with the α,β‐unsaturated aldehydes (II) or by an isomerization reaction of the 3,5‐dienenitrile (IV) as outlined in the reaction scheme.
ChemInform Abstract: Interconversion of Gas‐Phase Arenium Ions and π‐Complexes.
Authors: HOLMAN R. W. , GROSS M. L.
Published: May 2016

σ‐Complexes such as (I) dissociate to give the arenium ion (II) and the alkene (III).
ChemInform Abstract: Magnetic Field Effects in Cobalt(II)‐Catalyzed Oxidations: The Role of Electron Spin Angular Momentum.
Authors: HUGHES M. E. , CORDEN B. B.
Published: May 2016

The initial rate of the oxidation of (I) to give (II) is increased using cat1, a high‐spin Co(II) complex (S = 3/2) and is decreased using cat2, a low‐spin Co(II) complex (S = 1/2).
ChemInform Abstract: Exchange Type Reactions Between Oxiranes or Thiiranes and 2‐Hydroxyalkyl or 2‐Thioalkyl Amines and Sulfides.
Authors: WILK K. A.
Published: May 2016

The interaction of oxiranes with N‐alkyl‐bis(2‐hydroxyl)amines leads to the formation of an ammonium zwitter ion which is unstable.
ChemInform Abstract: Alkylidene Sulfur Difluorides: F5S(CF3)C=SF2 and (CF3)2C=SF2. Synthesis, Structure and Structure Predictions.
Authors: DAMERIUS R. , SEPPELT K. , THRASHER J. S.
Published: May 2016

The compounds (III) and (VI) rearrange quantitatively by light or heat to give the corresponding sulfenylfluorides (IV) and (VII).
ChemInform Abstract: γ‐Silicon Effects on 2‐Norbornyl Cations.
Authors: KIRMSE W. , SOELLENBOEHMER F. +
Published: May 2016

The solvolysis of (I) gives a mixture of the nortricyclenes (II) and (III).
ChemInform Abstract: Preparation of 1‐Phenylthio‐1,3‐dienes by Reaction of 2,5‐Dihydrothiophenes with Benzyne Through Fragmentation of Sulfonium Ylide Intermediates.
Authors: NAKAYAMA J. , KUMANO Y. , HOSHINO M.
Published: May 2016

The dihydrothiophenes (I) are cleaved upon reaction with aryne, generated from o‐carboxybenzenediazonium chloride (II), forming the dienyl phenyl sulfides (III), together with the dehydrogenated thiophenes (IV).
ChemInform Abstract: Synthesis of 8‐(Methoxycarbonyl)(6)paracyclophane‐3,4‐dione.
Authors: TOBE Y. , FURUKAWA T. , KOBIRO K. , KAKIUCHI K. , ODAIRA Y.
Published: May 2016

Hydroxylation of the propelladienone (I) followed by protection with 2,2‐dimethoxypropane (II) yields the isomeric isopropylidene derivatives (III) and (IV).
ChemInform Abstract: α‐Allylation of β‐Tetronic Acids and Chirality Transfer via the 4‐Oxygenated 2(5H)‐Furanone System.
Authors: MOMOSE T. , TOYOOKA N. , FUJII H. , YANAGINO H.
Published: May 2016

Reaction of the tetronic acids (I) and (V) with allyl bromide (II) gives the C‐ and O‐allylation products as shown in the reaction scheme.
ChemInform Abstract: Lewis Acid‐Catalyzed Diels‐Alder Reactions of 1‐Phenyl‐Substituted 3‐Vinylindoles with N‐Phenylmaleimide. Hints at Concerted and Nonconcerted Processes.
Authors: PINDUR U. , PFEUFFER L.
Published: May 2016

(4 + 2)Cycloaddition reaction of the N‐(sulfonyl)vinylindole (Ia) with the maleinimide (II) gives a small amount of the endo‐cycloadduct (IIIa) as the sole product, while the N‐(methyl)vinylindole (Ib) gives a mixture of the cycloadducts (IIIb) and (IVb).
ChemInform Abstract: Gossypol and Hemigossypols. Part 3. Preparation of the Methyl Gossypol Methylene Ether.
Authors: DALLACKER F. , LEUTHER P. , WABINSKI‐WESTEROP K.
Published: May 2016

The hydroxynaphthodioxoles (I) are dimerized by oxidation with potassium hexacyanoferrate(III) and subsequent reductive work‐up with dithionite to give the dimer (II).
ChemInform Abstract: Syntheses of Symmetric α,α,α‐Tris(imidazolylmethyl)acetonitriles: A New Class of Tripod M2+‐Chelating Ligands.
Authors: MANOHARAN T. S. , BROWN R. S.
Published: May 2016

Base‐catalyzed coupling of the N‐protected chloromethylimidazole (II) with acetonitrile (I) yields the tris‐substituted acetonitrile (III) which is deprotected by aqueous acid, giving the compound (IV).
ChemInform Abstract: Stereoselectivities of Mesitonitrile Oxide Cycloadditions to 7‐Substituted Norbornadienes.
Authors: DAL BO L. , DE AMICI M. , DE MICHELI C. , GANDOLFI R. , HOUK K. N.
Published: May 2016

1,3‐Dipolar cycloaddition reaction of mesitonitrile oxide (II) with the norbornadienes (I) gives the isomeric cycloadducts (III) ‐ (VI).
ChemInform Abstract: Nonacidic and Highly Chemoselective Protection of the Carbonyl Function. 3‐Methylbenzothiazolines as a Base‐ and Acid‐Resistant Protected Form for the Carbonyl Groups.
Authors: CHIKASHITA H. , KOMAZAWA S. , ISHIMOTO N. , INOUE K. , ITOH K.
Published: May 2016

An efficient method for the protection and deprotection of aldehydes and ketones such as (II) under mild and neutral conditions is achieved by conversion into the 3‐methylbenzothiazolines (III).
ChemInform Abstract: Studies on Diazepines. Part 30. Addition Reactions of Monocyclic Diazepines with Dimethyl Acetylenedicarboxylate Involving Diazonine Intermediates.
Authors: KURITA J. , KUKUSAWA N. , TSUCHIYA T.
Published: May 2016

The 1,3‐diazepines (I) react with the diester (II) mentioned in the title to give the pyrrolopyridines (III).
ChemInform Abstract: Sparsomycin Analogues. Part 5. Synthesis and Antitumor Activity of E‐β‐(Pyrimidin‐5‐yl)acrylamides.
Authors: KANATOMO S. , WADA A. , HAMAOKA Y. , NAGAI S. , FUKUDA S. , TANAKA M. , SASAKI T.
Published: May 2016

The sparsomycin analogs L‐(III) are synthesized from the pyrimidinylacrylic acids (I) and the methyl methioninates L‐(II) using the mixed anhydride method.
ChemInform Abstract: Synthesis of 1′‐Substituted 2‐Aminospiro(4H‐3,1‐benzoxazine‐4,4′‐piperidine) Derivatives.
Authors: TAKAI H. , OBASE H. , TERANISHI M.
Published: May 2016

Cyclization of the ureas (III), prepared from the anilines (I) and the isocyanates (II), in concentrated hydrochloric or sulfuric acid yields the benzoxazines (IV).
ChemInform Abstract: Cyclic Borates Prepared from Shikimic and Quinic Acid and Their Methyl Esters ‐ Structure and Stability in Aqueous Solution.
Authors: DELFOURNE E. , VERONIQUE J. , GORRICHON L. , MUNOZ A. , LAMANDE L.
Published: May 2016

Interactions between B(OH)3 (III) and the acids/esters (I) and (II) are studied by means of 11B and 13C NMR.
ChemInform Abstract: Selective H/D Exchange in Alkylsilanes Catalyzed by Osmium Phosphine Complexes: The First Evidence for β‐Hydrogen Elimination from a Metal Silyl.
Authors: BERRY D. H. , PROCOPIO L. J.
Published: May 2016

NMR studies of the exchange reactions show them to proceed by formation of transient silene complexes which formally represent the dehydrogenation of the silane within the Os coordination sphere.
ChemInform Abstract: Carbohydrate Metal Ion Complexes. Interaction of D‐Glucono‐1,5‐lactone with Zn(II), Cd(II), and Hg(II) Ions in the Solid and Aqueous Solution, Studied by 13C‐NMR, FT‐IR, and X‐Ray Powder Diffraction Measurements.
Authors: TAJMIR‐RIAHI H. A.
Published: May 2016

The reaction of the title lactone with Zn(II), Cd(II), and Hg(II) carbonates in aqueous solution is studied.
ChemInform Abstract: Coordination Compounds of Indium. Part 45. Indium(I) Derivatives of Aromatic Diols.
Authors: MABROUK H. E. , TUCK D. G.
Published: May 2016

The electrochemical oxidation of anodic In(0) (I) in solutions of the aromatic diols (II) yields the new In(I) compounds (III).
ChemInform Abstract: Organotin Compounds. Part 11. Organotin Hydride Additions to Various Methyl Dihydronaphthalenecarboxylates.
Authors: PODESTA J. C. , AYALA A. D. , CHOPA A. B. , GIAGANTE N. N.
Published: May 2016

Diastereoselective hydrostannylation of the dihydronaphthalenecarboxylates (I), (V), and (VIII) gives the trialkylstannyltetralincarboxylates (III), (VI), and (IX) via free radicals.
ChemInform Abstract: Nucleophilic Aromatic Substitutions SNAr of Fluorobenzenetricarbonylchromium.
Authors: ROSE‐MUNCH F. , ROSE E. , SEMRA A. , MIGNON L. , GARCIA‐ORICAIN J. , KNOBLER C.
Published: May 2016

Reactions of the fluorobenzene complexes (I) and (IV) with the carbanions of (II), (V), and (VII) give the cine‐ and tele‐nucleophilic aromatic substitution products (III), (VI), and (VIII).
ChemInform Abstract: Synthesis and Reactivity of Ruthenium Hydride Complexes of Chelating Triphosphines. Part 2. X‐Ray Structure Determination of the Novel Compound Ru(CCPh)(η3‐PhC3CHPh)(Cyttp)(Cyttp: C6H5P(CH2CH2CH2P(c‐C6H11)2)2).
Authors: JIA G. , RHEINGOLD A. L. , MEEK D. W.
Published: May 2016

The novel title complex (III) contains an unusual C‐C coupling product as ligand.
ChemInform Abstract: Synthesis of Salvilenone, a Diterpenoid Phenalenone of Salvia miltiorrhiza.
Authors: ZHENG G.‐C. , KAKISAWA H.
Published: May 2016

Salvilenone (X) is a minor constituent of the title plant.
ChemInform Abstract: A Simple and Efficient Method for the Preparation of Binaltrorphimine and Derivatives and Determination of Their ϰ Opioid Antagonist Selectivity.
Authors: SCHMIDHAMMER H. , SMITH C. F. C.
Published: May 2016

The title compound (IIIa) and its derivative (IIIb) possess antagonist potency and κ selectivity.
ChemInform Abstract: Order‐Disorder Transitions of the Pd7Dy(Y) Phase in Pd‐Dy(Y) Alloys.
Authors: TAKAO K. , SAKAMOTO Y. , YOSHIDA M. , FLANAGAN T. B.
Published: May 2016

An ordered phase in the form of a Pd7Dy(Y) superlattice is detected in annealed Pd‐Dy and Pd‐Y alloys containing 8‐17.5 at.% Dy(Y).
ChemInform Abstract: Metal Derivatives of Molecular Compounds. Part 2. Preparation and Structure of β‐Potassium Silanide.
Authors: MUNDT O. , BECKER G. , HARTMANN H.‐M. , SCHWARZ W.
Published: May 2016

A hitherto unknown low‐temp.
ChemInform Abstract: The First Quaternary Oxostannate with Isolated Anion Structure: RbNa3(SnO4)
Authors: BERNET K. , HOPPE R.
Published: May 2016

is prepared by heating a mixture of RbSn and Na2O2 at 750 °C (Rb:Na = 1:4, Ni‐tube, 21 d).
ChemInform Abstract: “Lithovanadates”: Rb2(LiVO4) and Cs2(LiVO4)
Authors: KISSEL J. , HOPPE R.
Published: May 2016

are prepared by heating mixtures of the corresponding binary oxides at 750 °C (Ni‐tube, 25 d).
ChemInform Abstract: Contributions to the Investigation of Inorganic Nonstoichiometric Compounds. Part 36. Tungsten‐Rich Solid Solution Series of (Nb,W)Ox Phases Having Block Structures ‐ Preparation by Chemical Transport.
Authors: HUSAIN A. , GRUEHN R.
Published: May 2016

Large crystals of four series of solid solutions denoted as 6:1 (W4/4(Nb12O33)), 7:3 (W4/4(Nb14W2O44)), 8:5 (W4/4(Nb16W4O55)), and 9:8 (W4/4(Nb18W7O69)) phases having block structures with building units of (3 · 4), (4 · 4), (4 · 5), and (5 · 5), resp., are prepared from Nb2O5, WO3, and NbO2 by nearly isothermal transport (∼1250 °C) using HgCl2 as mineralizer.
ChemInform Abstract: SNAr, SN2, and Aromatic Addition Processes in the Reactions of Picryl Ethers with Nitrogen and Carbon Bases.
Authors: STRAUSS M. , TORRES R.
Published: May 2016

The picryl ethers (I) are treated with triethylamine (III) or diethylamine (VII) in various solvents: e.g., (I) and (III) react with di‐(methoxycarbonyl)acetone (II) in methylene chloride to form the bridged trinitro compounds (IV) and (V), together with the substitution product (VI).
ChemInform Abstract: 2,4‐Dimethylene‐1,3‐cyclobutanediyl (VII), the Non‐Kekule Isomer of Benzene. Synthesis, EPR, and Electronic Spectroscopy.
Authors: SNYDER G. J. , DOUGHERTY D. A.
Published: May 2016

Starting from benzvalene (I), a wide range of reactions are examined to obtain diazene (VI), the immediate precursor of diyl (VII).
ChemInform Abstract: Optimization of the Reaction Conditions Using a NADH Model Grafted on a Merrifield Type Resin.
Authors: DUPAS G. , DECORMEILLE A. , BOURGUIGNON J. , QUEGUINER G.
Published: May 2016

The synthesis of reducing agent (I), 1,4‐dihydronicotinamide grafted on a Merrifield resin, through quaternization of nicotinamide with the Merrifield resin in refluxing MeCN followed by Na2S2O4 reduction, is described.
ChemInform Abstract: Biotransformations with Halobacterium halobium: Reduction of Ethyl 3‐Oxobutanoate and Hydrolysis of Ethyl 3‐Hydroxybutanoate. Cooperative Effects of Reductase and Hydrolase.
Authors: EHRLER J. , SEEBACH D.
Published: May 2016

The title bacterium is tested for its ability to achieve biotransformations, but only a small variety of compounds such as (I) or (±)‐(II) are accepted as substrates.
ChemInform Abstract: Importance of Structure of α,β‐Ethylenic Ketones During Their Reductive Coupling Promoted by the TiCl4‐Mg Reagent.
Authors: PONS J.‐M. , SANTELLI M.
Published: May 2016

The reductive coupling of various α,β‐unsaturated ketones is performed using the TiCl4‐Mg system under different conditions.
ChemInform Abstract: Radiotracers in Fluorine Chemistry. Part 12. Reactions Between Cesium Fluoride and Arsenic Pentafluoride, Boron Trifluoride, Sulfur Tetrafluoride, Carbonyl Fluoride, and Carbon Dioxide Under Heterogeneous Conditions at Room Temperature. Radiotracer Studies Using Fluorine‐18, Sulfur‐35, and Carbon‐14.
Authors: DIXON K. W. , WINFIELD J. M.
Published: May 2016

Activation of CsF by thermal decomposition of its 1:1 adducts with hexafluoroacetone or carbonyl fluoride results in significantly greater activity with respect to its reactions with AsF5, BF3, and SF4, and enables reactions involving carbonyl fluoride and CO2 to be studied.
ChemInform Abstract: New Alkoxycarbonylalkyloxychalcones and Their α,β‐Dibromo Derivatives of Potential Antimicrobial Activity.
Authors: SZAJDA M. , KEDZIA B.
Published: May 2016

The p‐hydroxychalcone (I) is coupled with the bromoacetates (II) to give the unsaturated phenol ethers (III) which react with bromine to form the brominated ethers (IV).
ChemInform Abstract: A Chiral Catechol with C2 Symmetry.
Authors: KELLY T. R. , CHANDRAKUMAR N. S. , SAHA J. K.
Published: May 2016

Starting with the dimethoxyphenylpropionate (I), the indacenedione (VIII) is prepared via the diester (V) and twofold cyclization of the dibromo acid (VI).
ChemInform Abstract: Synthesis and Reactivity of Furan‐2,3‐dione Derivatives.
Authors: ZANKOWSKA‐JASINSKA W. , BOROWIEC H. , BURGIEL M. , KOLASA A. , WODZIEN M.
Published: May 2016

The title compounds (III) are stable in weak acidic medium and cleaved in alkaline or alcoholic solution.
ChemInform Abstract: Glycolaldehyde Monomer in Organic Synthesis.
Authors: DINPRASERT P. , MAHIDOL C. , THEBTARANONTH C. , THEBTARANONTH Y.
Published: May 2016

Glycolaldehyde (II), generated in situ from its dimer (I) via formation of lithium alkoxides, reacts with the methyl carboxylates (III) in the presence of zinc chloride to yield the hydroxy γ‐lactones (IV).
ChemInform Abstract: Synthesis of 5‐Carbamoyloxy and 5‐Acyloxynaphthalene‐1,8‐carbolactones with Potential Antitumoral Activity.
Authors: BOUAZIZ Z. , FILLION H.
Published: May 2016

The hydroxynaphthalenecarbolactone (I) reacts with the isocyanates (II) to give the carbamates (III).
ChemInform Abstract: Synthesis and Pesticidal Activities of Some 1,3,4‐Thiadiazolo(3,2‐a)‐s‐triazine‐5‐thiones and 1,3,4‐Thiadiazolo(3,2‐a)imidazol‐6‐ones.
Authors: CHATURVEDI B. , TIWARI N. , NIZAMUDDIN NIZAMUDDIN
Published: May 2016

The title compounds (IV) and (VI) are tested for their pesticidal activity.
ChemInform Abstract: Synthesis and SAR Studies in 2‐Substituted 1,2,3,4‐Tetrahydro‐9H‐pyrido(3,4‐b)indole‐3‐carboxylic Acids ‐ a New Class of Potent Antiulcer Agents.
Authors: TRIPATHI R. CH. , PATNAIK G. K. , SAXENA A. K.
Published: May 2016

Eighteen title compounds of type (VI) are prepared via the corresponding esters of type (V).
ChemInform Abstract: Fluorocinnoline Derivatives. Part 2. Synthesis and Antibacterial Activity of Fluorinated 1‐Alkyl‐1,4‐dihydro‐4‐oxocinnoline‐3‐carboxylic Acids.
Authors: MIYAMOTO T. , MATSUMOTO J.
Published: May 2016

Treatment of the fluorinated cinnoline derivatives (I) with dialkyl sulfates (II) or the alkyl iodides (III) leads to the formation of the alkylated products (IV), together with the isomeric anhydro‐bases (V).
ChemInform Abstract: New Methods and Reagents in Organic Synthesis. Part 78. Reaction of Trimethylsilyldiazomethane with Olefins.
Authors: AOYAMA T. , IWAMOTO Y. , NISHIGAKI S. , SHIOIRI T.
Published: May 2016

Treatment of the olefins (I) with trimethylsilyldiazomethane (II) in the presence of palladium(II) chloride or cuprous chloride produces in general mixtures of the cyclopropanes (III) and (IV).
ChemInform Abstract: Cp2TiPh2‐Catalyzed Dehydrogenative Coupling of Polyhydromonosilanes.
Authors: NAKANO T. , NAKAMURA H. , NAGAI Y.
Published: May 2016

Diphenyltitanocene‐catalyzed reaction of diphenylsilane (I) yields the tetraphenyldisilane (II) and triphenylsilane (III).
ChemInform Abstract: Acetoxyselenenylation of Olefins for the Preparation of Vinylic and Allylic Acetates.
Authors: ENGMAN L.
Published: May 2016

When the terminal olefins (I) are treated with phenylselenenyl bromide (II) in acetic acid (III), mixtures of the α‐acetoxy selenides (IV) and (V) are formed.
ChemInform Abstract: Synthesis and Pyrolysis of Organoelement Benzazole Derivatives of Phosphorus, Arsenic, Silicon, and Tin.
Authors: HEINICKE J.
Published: May 2016

The isonitrile (I) reacts with the lithium reagent (II), forming the intermediate (III) which is coupled with dichlorides such as (IV), producing the organoelement benzazoles (V).
ChemInform Abstract: Synthesis of Nauclefine, Angustidine, Angustine, (.+‐.)‐13b,14‐Dihydroangustine and Naulafine.
Authors: REPKE D. B. , JAHANGIR JAHANGIR , CLARK R. D. , NELSON J. T. , MACLEAN D. B.
Published: May 2016

The title compounds (±)‐13b,14‐dihydroangustine (VIc), nauclefine (VIIa), angustidine (VIIb), angustine (VIIc) and naulafine (XI) are prepared using a common methodology.
ChemInform Abstract: Kinetic Study on Chemical Vapor Deposition of Titanium Disulfide Thin Film.
Authors: KANEHORI K. , KIRINO F. , ITO Y. , MIYAUCHI K. , KUDO T.
Published: May 2016

TiS2 films having a crystallographic orientation in which the c‐axis is parallel to the substrate (Si single crystals, borosilicate glass plates) plane are prepared by low pressure CVD using TiCl4 and H2S as source gases and conditions where the reaction is controlled by the surface reaction.
ChemInform Abstract: Formation of Chromium Interlayers in α‐Zirconium Phosphate.
Authors: MACLACHLAN D. J. , BIBBY D. M.
Published: May 2016

Refluxing of the half‐sodium‐exchanged form of α‐zirconium bis(hydrogenphosphate) (Zr(PO4)2)NaH·5 H2O with solutions of Cr(OAc)3 results in interlayered materials with expanded interlayer spacings (15‐26 Å).
ChemInform Abstract: Crystal Structures and Properties of Two Sodides and an Electride.
Authors: DAWES S. B. , WARD D. L. , FUSSA‐RYDEL O. , HUANG R.‐H. , DYE J. L.
Published: May 2016

Compound (I) crystallizes in the space group C2/m with Z=2; (II) in C2/c with Z=4.
ChemInform Abstract: Baeyer‐Villiger Reaction in Water.
Authors: FRINGUELLI F. , GERMANI R. , PIZZO F. , SAVELLI G.
Published: May 2016

The title reaction of substrates such as (I), (III), (V) in water are fast and occur in high yields.
ChemInform Abstract: Oxidative δ‐Chlorination of Aliphatic Alcohols with the System Lead Tetraacetate‐Metal Chloride.
Authors: KAPUSTINA N. I. , LISITSYN A. V. , NIKISHIN G. I.
Published: May 2016

Oxidative chlorination of the primary alcohols (I), the secondary alcohols (VIa) or (VIb), and the tertiary alcohol (IX) with the system lead (IV) acetate/metal chloride predominantly gives the δ‐chloro alkanols (II), (VIIa) or (VIIb), and (X).
ChemInform Abstract: Perfluoroalkylations of Nitrogen‐Containing Heteroaromatic Compounds with Bis(perfluoroalkanoyl) Peroxides.
Authors: YOSHIDA M. , YOSHIDA T. , KOBAYASHI M. , KAMIGATA N.
Published: May 2016

Perfluoroalkylations of the heteroaromatic compounds (II), (IV), (VI) using the bis(perfluoroalkanoyl) peroxides (I) afford the products (III), (Va) + (Vb), or (VII).
ChemInform Abstract: Selective 1,2‐Addition of Organo‐Cerium(III) Reagents to α,β‐Unsaturated Carbonyl Compounds.
Authors: IMAMOTO T. , SUGIURA Y.
Published: May 2016

A suspension of cerium trichloride (I) is treated with the organo‐lithium compounds (II), forming the organo‐cerium agents (III) which react with the α,β‐unsaturated carbonyl compounds (IV) to give predominantly the allylic alcohols (V), together with the saturated compounds (VI).
ChemInform Abstract: Oxidation of Methacrylic Acid Esters with H2O2 in Presence of Chromium Catalysts. A Novel Route to Pyruvic Acid Esters.
Authors: INOUE M. , URAGAKI T. , KASHIWAGI H. , ENOMOTO S.
Published: May 2016

The methacrylates (I) are converted to the pyruvates (II) by oxidation with aqueous H2O2 in the presence of chromium catalysts.
ChemInform Abstract: Asymmetric Aldol Reaction of Silyl Enol Ethers with Aldehydes Promoted by the Combined Use of Chiral Diamine‐Coordinated Tin(II) Triflate and Tributyltin Fluoride.
Authors: KOBAYASHI S. , MUKAIYAMA T.
Published: May 2016

The aldehydes (I) are coupled with the O‐silyl ketene O,S‐acetales (II) in the presence of tin triflate, tributyltin fluoride, and a chiral pyrrolidinylmethylpiperidine to form the optically active β‐hydroxy thiolo esters (III).
ChemInform Abstract: Reaction of Polyhalogenated Disulfides with Hexaethylphosphorous Triamide.
Authors: POPKOVA V. YA. , GALAKHOV M. V. , KNUNYANTS I. L.
Published: May 2016

Treatment of the symmetric disulfides (I) and (III) with hexaethylphosphorous triamide gives the thiiranes (II) and (IV).
ChemInform Abstract: Highly Enantiospecific Synthesis of 4‐Alkyl and 4,5‐Dialkyl Substituted 4,5‐Dihydrofuran‐2(3H)‐ones from Optically Active (E)‐ and (Z)‐Alk‐1‐enyl p‐Tolyl Sulfoxides: Application to the Synthesis of Lignan Lactones.
Authors: KOSUGI H. , TAGAMI K. , TAKAHASHI A. , KANNA H. , UDA H.
Published: May 2016

The Z‐(I) and E‐(III) sulfoxides are obtained from the acetylenic sulfoxides (II) by different reduction methods as shown in the scheme.
ChemInform Abstract: Base‐Catalyzed Condensation of 2,5‐Dimethyl‐1‐phenylpyrrole‐3,4‐dicarbaldehyde with β‐Diketones.
Authors: VORKAPIC‐FURAC J. , SUPRINA M.
Published: May 2016

The pyrroledicarbaldehyde (I) and the diketones (II) cyclize to give the cycloheptapyrrolones (III) or a mixture of (IIIa) and the dihydrocycloheptapyrrolone (IV) depending on the reaction conditions.
ChemInform Abstract: Synthesis of New Anellated Flavonoid Derivatives Possessing Spasmolytic Activity. Part 7.
Authors: ERTAN R. , GOEKER H. + , ERTAN M. , PINDUR U.
Published: May 2016

Cyclocondensation of 7,8‐dihydroxyflavone (I) with 2,3‐dibromopropanoate (II) give a regioisomeric mixture of the anellated 1,4‐benzodioxanes (III) and (IV).
ChemInform Abstract: Quinoxalines. Part 25. Synthesis and Chemical Properties of 2‐Nitroquinoxaline.
Authors: IIJIMA C.
Published: May 2016

2‐Iodoquinoxaline (I) is converted to the 2‐nitro compound (III) by reaction with silver nitrite (II).
ChemInform Abstract: Rearrangements of Arylhydrazones of N‐Acylbenzimidazoles. Synthesis of 2‐Aryl‐1,2,4‐triazolo(4,3‐a)quinoxalinium Salts.
Authors: CUSMANO G. , MACALUSO G.
Published: May 2016

The hydrazones (I), (III), and (VII) undergo acid‐catalyzed cyclization reaction to produce the triazolium perchlorates (II), (IV), and (VIII).
ChemInform Abstract: Pteridines. Part 88. Oxidations and Reactions of 2‐ and 4‐Thiolumazine Derivatives. Synthesis and Properties of Pteridinesulfinates and Pteridinesulfonates.
Authors: BARTKE M. , PFLEIDERER W.
Published: May 2016

The thiolumazines (I) are oxidized with H2O2, forming the stable sulfinates (III) which release SO2 upon treatment with sulfuric acid to produce the pteridines (IV).
ChemInform Abstract: Cyclic Organophosphorus Compounds. Part 23. Configurational Assignments in the 4‐Phenyl‐1,3,2λ5‐dioxaphosphorinane Series. X‐Ray Molecular Structure of cis‐2‐Benzylamino‐4‐phenyl‐1,3,2‐dioxaphosphorinane 2‐Oxide.
Authors: EDMUNDSON R. S. , FORTH I. , KING T. J.
Published: May 2016

Chlorine displacement in (I) by the amine (II) gives the cis product (III) (space group C2/c).
ChemInform Abstract: Complex Hydrogen‐Bonded Cations. X‐Ray Crystal Structure of (((C6H5CH2)NH3)4Cl) (AlCl4)3 and Its Relevance to the Structure of Basic Chloroaluminate Room‐Temperature Melts.
Authors: DUBOIS R. H. , ZAWOROTKO M. J. , WHITE P. S.
Published: May 2016

The title compound (IV) crystallizes in P1.