bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital Access Brokers: Clustering and Comparison (Part I – Locator Services)
Authors: Bijan Kumar Roy  , Parthasarathi Mukhopadhyay
Published: November 2022

Scholarly resources published on different platforms are not often searchable and accessible to potential scholars. Google, like other search engines, does not always retrieve free articles on a consistent basis. As a result, there is a gap between the availability and discoverability of scholarly resources. Digital Access Brokers are ground-breaking developments in this context that assemble, discover, and link to open access copies of paid articles or paywalled papers legally uploaded by authors or author-posted manuscripts, with permission from publishers. Browser extensions have emerged as an alternative retrieval assistant to help scholars locate and provide free full-text access to such content available on different publisher sites, databases, open-access journals, or institutional repositories. Unlike other search engines, these extensions provide additional value-added services (such as recommending related resources, citation information, status, type of open access license, level of access and availability of copies by indicating different colours, integration with citation management tools, article metrics) along with the paper to reduce the information overload of the readers. The objective of this paper is to provide an idea about different browser extensions such as Kopernio, Open Access Button, Unpaywall, and along with their key features that might help them in selecting the best tool for their research work.
Del virreinato a la utopía republicana: El imaginario patriótico a la realidad vivencial en el sur del Perú (1780-1823)
Authors: Osorio Soto Gary Martín
Published: November 2022

La presente investigación tiene como finalidad evidenciar la concepción social e ideológica del poblador de las regiones del sur del Perú (Tacna y Arica) en el contexto del proceso de emancipación e independencia del Perú. Mediante el abordaje multidisciplinar podemos evidenciar la dicotomía entre hechos históricos y el discurso patriótico mediante la comparación de la evidencia documental y testimonial del proceso de emancipación. La objetividad histórica se ha visto distorsionado en base a la elaboración del imaginario patriótico nacional peruano a costa de las relaciones sociales y humanas de las poblaciones de Tacna y Arica entre 1780-1823. El discurso patriótico, fue generado a través del conflicto, rompiendo las raíces de conexión simbólica entre la nobleza ibérica e incaria, transfigurando las raíces ibero – puquina que gobernaban en el sur del reino del Perú. Con el presente artículo abordaremos la inverosimilitud del discurso patriótico e indigenista que promovió el proceso de independencia.
Eating styrofoam balls presented as intestinal obstruction- PICA associated with bezoar: a rare case report and review of literature
Authors: Haji Altaf G. , Sivakumar Naveen , Piramanayagam Bala , Palit A.
Published: November 2022

Gastrointestinal obstruction secondary to foreign body bezoars (industrial materials, plastic, tissue paper, sponge) have been reported but foreign body bezoar with styrofoam has never been reported in literature. PICA associated bezoars are an unusual complication and reports say that a wide variety of substances are consumed, ranging from socks, newspapers, and sofa pillows to dirt and hair and in this case, it was ingestion of styrofoam balls. Styrofoam being foam plastic does not breakdown or get absorbed in body when ingested, but its persistent ingestion creates bezoar which can fill the whole gastrointestinal tract.
Dens evaginatus: a cause of periapical pathology in caries-free teeth
Authors: John Sosham
Published: November 2022

There are morphological variations reported in both primary and permanent dentition. This case report describes the presentation of dens evaginatus causing periapical pathology in a caries-free mandibular second premolar. The tubercle-like presentation of dens evaginatus interferes with the occlusion of posterior teeth. Occlusal wear caused exposure of the pulp within the cusp resulting in pulpal necrosis and, eventually, periapical pathology. Proper diagnosis and management by root canal treatment resulted in the resolution of the symptoms and complete healing.
DEPREDACIÓN DE GRISÓN GRANDE (Galictis vittata) POR ÁGUILA HARPÍA Harpia harpyja
Authors: Maldonado Casanova Gabriel Enrique , Ninabanda Ramiro , Licuy Mayra
Published: November 2022

En esta nota de campo presentamos el registro  de un individuo juvenil de Águila Harpía (Harpía harpyja) alimentándose de un Hurón (Galictis vittata) en la Amazonía ecuatoriana.
La desigualdad de la distribución de ingresos en el Perú : orígenes históricos y dinámica política y económica
Authors: Contreras Carlos , Incio Coronado José Luis , López Sinesio , Mazzeo Cristina Ana , Mendoza Waldo
Published: November 2022

El Perú, a inicios del siglo XXI, además de haber logrado los mejores resultados en reducción de pobreza e inflación, aparece como el país que lidera el crecimiento económico en América Latina, a tal punto que hoy se habla del «milagro peruano». Sin embargo, el país sigue siendo profundamente desigual, según confirman las cifras de distribución del ingreso. Carlos Contreras, José Incio, Sinesio López, Cristina Mazzeo y Waldo Mendoza, autores de este libro, responden una serie de interrogantes como: ¿Cuáles son las razones que explican este alto grado de desigualdad? ¿Nuestra herencia colonial ha tenido un papel en esta materia? ¿Cuál ha sido la relación entre la política peruana y las diferencias en el ingreso desde mediados del siglo XX hasta la actualidad? ¿Cómo y por qué se han ido modificando estas desigualdades durante las últimas seis décadas en el Perú? Este libro enfrenta de manera interdisciplinaria a estas y otras interrogantes cuyas respuestas no solo explican nuestra realidad sino que pueden, si se analizan correctamente, ayudar a definir un mejor rumbo para nuestro país.
En busca de reconocimiento : reflexiones desde el Perú diverso
Authors: Ulfe María Eugenia , Trinidad Rocío
Published: November 2022

Este libro reúne algunas de las ponencias presentadas en el seminario internacional «Políticas de reconocimiento, de diferencia y de ciudadanía», realizado en la PUCP en octubre de 2012, así como otros artículos que se sumaron en el camino, editados por María Eugenia Ulfe y Rocío Trinidad. Todos estos textos evidencian las distintas formas en que los sujetos utilizan el lenguaje, los repertorios y las estrategias de reconocimiento para visibilizar demandas puntuales en el espacio público y en la cultura pública del Perú. El libro analiza las memorias nacionales y locales de Ayacucho, Canta y Huanta en diferentes momentos para, a partir de allí, repensar la manera en que se gesta la historia como proceso. Luego aborda los movimientos y movilizaciones que realizan los pueblos indígenas amazónicos y los grupos sociales urbanos para que el Estado reconozca su identidad, su territorio y su ciudadanía. Además, se evidencian la negación y el rechazo al reconocimiento de la diversidad y al ejercicio pleno de la ciudadanía a través de la unión civil y el derecho a la identidad de género. Finalmente, examina estrategias de reconocimiento desde el arte, la psicología y el marketing. En suma, este libro busca contribuir no solo a teorizar, sino a poner en práctica el debate sobre el reconocimiento como elemento fundamental para la vida social basada en deberes y derechos.
La adolescencia es más que una palabra
Authors: Coloma Manrique Carmen Rosa , Piscoya Rivera Leonardo
Published: November 2022

El artículo no presenta resumen.
La participación docente en la toma de decisiones desde la visión micropolítica
Authors: Obando Castillo Gustavo
Published: November 2022

El docente es quien vive de cerca la problemática de la escuela, quien concreta,tergiversa o sabotea los planes de acción, quien transmite la visión institucional ola dificulta, entre otros aspectos; lo cual lo revelan como pieza clave para la vida delas organizaciones educativas. Por ello es importante que participe en las escuelasde forma real, es decir, que intervenga en la toma de decisiones.Sin embargo, en un contexto micropolítico, la participación puede darse demanera compleja y no siempre abierta, empleando una serie de estrategias comoalianzas, rumores y chismes, para que los diversos grupos e individuos alcancensus intereses, los que no necesariamente están alineados con los de la escuela o conlos de los demás grupos.
Razones para jugar: hacia la comprensión del rol del juego en el proceso de formación de docentes de educación inicial
Authors: Mendívil Trelles de Peña Luzmila
Published: November 2022

El artículo tiene el propósito de justificar la necesidad de reorientar los procesos de formación, con miras a producir cambios en las prácticas docentes en el nivel de educación inicial. Desde una perspectiva crítica cuestiona la formación académica teórica, alejada de la vida y experiencias concretas de los niños, replanteando la centralidad del juego en la formación inicial, no solo como un referente teórico instrumentalizado para mejorar procesos de aprendizaje, tal como es en efecto en la vida humana y social. Asimismo, recupera el componente emocional como promotor de procesos de cambio.
Estudio comparativo de estructuras de educación y atención a la infancia en siete países: Australia, Bélgica, Brasil, Canadá, Cuba, Francia y Perú
Authors: Vargas D’Uniam Jessica
Published: November 2022

La investigación comprende la comparación de estructuras educativas de atención a los niños menores de seis años en siete países: Australia, Bélgica, Brasil, Canadá, Cuba, Francia y Perú.El interés por el tema surge por la necesidad de identificar y de analizar las estructuras educativas que atienden a los niños menores de seis años, a fin de conocer los mecanismos que desarrollan para responder a sus características y necesidades particulares.El análisis de los datos permitió concluir que la organización de las estructuras educativas destinadas a la atención de los niños pequeños depende de diversos factores (sociales, económicos, culturales, geográficos, etcétera) y que puedenconfigurar de manera diferente los servicios y programas de educación, a fin de responder a las características y a las necesidades de los niños, de sus familias y de la comunidad.
Opiniones sobre el desempeño docente y sus repercusiones en la satisfacción profesional y personal de los profesores
Authors: González Such José , Subaldo Suizo Lucía
Published: November 2022

En este trabajo se presenta una revisión sobre el desempeño docente y su relación con la satisfacción/insatisfacción personal y laboral del profesorado que repercute en el profesor y que puede conducir a desgaste en su salud y bienestar. El objetivo de este trabajo se centra en el conocimiento de las opiniones y vivencias del profesorado sobre el desempeño y sus repercusiones en la satisfacción laboral y personal del profesorado e identificar los factores fundamentales de satisfacción/ insatisfacción de los docentes. Los resultados indican que las experiencias positivas del profesorado en el ejercicio de la docencia producen satisfacción y conllevan el desarrollo y la realización personal y profesional, que tienen gran influencia en la enseñanza y el aprendizaje del alumnado, mientras que las experiencias negativas producen insatisfacción personal y profesional.
Investigating the Impacts of Mobile Assisted Reading on EFL Learners’ Vocabulary Knowledge Development
Authors: VALİZADEH Mohammadreza
Published: November 2022

Abstract. In recent years, the proliferation of mobile technologies is transforming educational practices around the world. In this regard, students are attending classes with their mobile or tablet devices, on which they do most of their reading and writing activities. This has resulted in new understanding of literacy as being multimodal, fluid, sociocultural, and dynamic social practices. Meanwhile, mobile-assisted language learning developed exponentially, and its implementation has been reported to be generally effective in language education compared to traditional materials. Within this line of research, the current study examined the impacts of mobile assisted reading on English language learners’ vocabulary development. The participants of the research were 52 adult language learners divided into one experimental and one control groups. The participants in the experimental group employed mobile devices for reading a number of selected and simplified news reports, however, the control group used traditional print-based materials for reading the same content over the course of 10 weeks. The participants’ vocabulary gains were compared in pre- and post-tests and the findings indicated that the two groups improved their vocabulary knowledge, but the experimental group learned more vocabulary items and outperformed the control group on post-test. The findings highlighted the significant contribution of mobile phones in improving second language reading with associated impacts on vocabulary development. The study has implications for language teachers and materials development in teaching English to speakers of other languages.
Pemaknaan Artefak Budaya dan Tuturan Perayaan Keagamaan
Authors: Rahardjo Turnomo , Hapsari Dwiningtyas Sulistyani  , Lintang Ratri Rahmiaji
Published: November 2022

This study was intended to comprehend how faith-based community groups communicated about cultural artifacts such as diverse Christmas celebration speeches. this study employed a phenomenological approach in order to understand the importance of identity expressions from the cultural artifacts associated with the Christmas season. This study found that faith-based community organizations interpret the issues of Christmas speeches or greetings differently. Muhammadiyah "frees" its adherents to wish Christians a Merry Christmas or not. Additionally, since Christmas characteristics were seen as examples of cultural inventiveness, it did not raise any objections to them. Congratulating the religious holidays of other religions, such as "Merry Christmas," are officially not prohibited by Nahdlatul Ulama. Similar circumstances apply to the Indonesian Chinese Islamic Association. With so many different religions practiced in Chinese society, sending presents and expressing congratulations during religious events is customary. Persatuan Islam and Majelis Mujahidin offered a different viewpoint. Because it goes against their beliefs, they generally resist sending christmas greetings.
Bismuth-Based Halide Perovskites for Photocatalytic H2 Evolution Application
Authors: Malavasi Lorenzo , Tedesco Costanza
Published: November 2022

Metal halide perovskites (MHPs), in particular lead-based halide perovskites have earned a recognized fame in several fields for their outstanding optoelectronics properties including direct generation of free charge carriers, optimal ambipolar charge carrier transport properties, high absorption coefficient, point-defect tolerance, and compositional versatility. Nowadays, this class of materials represents a real and promising alternative of silica for the photovoltaic technologies. This worthy success led to a growing interest in the exploration of MHP materials in other hot research fields such as the solar-driven photocatalytic water splitting towards hydrogen production, CO2 reduction to CO and CH4, useful organic reactions such as organic synthesis (formation of C-C, C-N, and C-O bonds), and pollutants and dye degradation. Nevertheless, many of these perovskite materials showed air and moisture instability problems that considerably hinder their practical application for photocatalytic water splitting and photodegradation of CO2. Moreover, if the chemical instability is a problem that can be in part mitigated by the optimization of the lattice structure, the presence of lead represents a real problem for the practical application of these type of materials in commercial devices. To successfully overcome this problem, lead-free metal halide perovskites (LFMHPs) have gained increasing interest thanks to their promising optoelectronic properties, comparable to lead-based materials, and their eco-friendly nature. Among all the lead-free perovskite alternatives, this mini review will focus the attention on the bismuth-based perovskites and perovskite derivatives with specific focus on solar-driven photocatalysis application for H2 evolution.
Comparison and Improvement of 3D-Multilateration for Solving Simultaneous Localization of Drones and UWB Anchors
Authors: Malivert Franck , Labbani-Igbida Ouiddad , Boeglen Hervé
Published: November 2022

Fleets of drones have attracted a lot of attention from the research community in recent years. One of the biggest challenges in deploying such systems is localization. While GNSS localization systems can only be effective in open outdoor environments, new solutions based on radio sensors (e.g., ultra-wideband) are increasingly being used for localization in various situations and environments. However, self-localization without prior knowledge of anchor positions remains an open problem which, for example, makes it impossible to track a moving target. In this article, we provide a comparison of different variants of gradient descent-based algorithms, with a new improved variant, for solving the localization problem using relative distance measurements and multilateration. It is applied to self-localization of anchors and tracking targets using ultra-wideband distance sensors. A realistic simulation of drone tracking and anchors’ localization is performed to demonstrate the robustness and accuracy of the proposed approach.
Community Health Assessment Tools Adoptable in Nursing Practice: A Scoping Review
Authors: Pazzaglia Chiara , Camedda Claudia , Ugenti Nikita Valentina , Trentin Andrea , Scalorbi Sandra , Longobucco Yari
Published: November 2022

The WHO European Region defined the role of a new central professional for primary care, the Family and Community Nurse (FCN). The introduction of FCN in the framework of health policies highlight a key role of nurses in addressing the families’ and communities’ needs. A scoping review was conducted in order to identify and describe the available tools which has been adopted for the assessment of the community health needs by FNC. A comprehensive literature review on Embase, Cochrane Library, PubMed, CINAHL, Scopus and PsycInfo databases was conducted including all studies up to May 2021. A total of 1563 studies were identified and 36 of them were included. The literature review had made possible to identify studies employing twelve different community assessment's tools or modalities. Referring the WHO framework proposed in 2001 some common themes have been identified with an uneven distribution, as profiling the population, deciding on priorities for action and public healthcare programmes, implementing the planned activities, evaluation of health outcomes, multidisciplinary activity, flexibility and involving the community. To the best of our knowledge, this work is the first attempt to provide an overview of community assessment tools, keeping the guidance provided by the WHO as a reference.
Temporal Dynamics of Soil Microbial Biomass C, N and P along an Altitudinal Gradient in Kumaun Himalayan Belt of India
Authors: Manral Vijyeta , Bargali Kiran , Bargali Surendra Singh , Karki Himani , Chaturvedi Ravi
Published: November 2022

This study assessed the periodic ﬂuctuations among microbial biomass Carbon (C), Nitrogen (N) and Phosphorus (P), and the consequences of variations in altitude and abiotic factors on the soil microbial biomass (C, N and P) in a temperate mixed-oak pine forest of Central Himalaya. This research was directed at three forest stands along an altitudinal gradient. Samples were collected in triplicates, seasonally from each selected site and microbial C, N and P were determined through the fumigation extraction method. Microbial biomass C, N and P decreased significantly (P<0.01, correlation coefficient -0.985, -0.963, -0.948, respectively) with increasing altitude, while the rainy season showed the highest values, and winter season revealed the least values. Microbial biomass C, N and P showed positive correlation with silt particles, water holding capacity, bulk density, porosity, soil moisture, organic C, total N and P, and negative correlations with sand particles and soil pH. The microbial biomass C showed strong associations with soil microbial N (r=0.80, P<0.01) and P (r=0.89, P<0.01) contents, while the soil microbial biomass N and P also showed strong positive correlation (r=0.92, P< 0.01). Soil microbial biomass was greatly inﬂuenced by the altitude and abiotic variables whereas, weakly by temporal variation. The microbial C: N ratio indicated that fertility of soil is inﬂuenced by the species assemblage. Our findings suggest that high microbial biomass and low C: N ratio during rainy season could be considered as a strategy to conserve nutrients by temperate mixed-oak pine forest ecosystem.
Effect of Various Nutraceuticals on Oncoprotein Heparan Sulfatase-2 Activity in Breast Cancer Cell Line
Authors: C. Hemakumar , Dharmesh Shylaja M. , Singh Ravendra Pratap
Published: November 2022

One in ten of all new cancers diagnosed worldwide are the cases of breast cancer and it is a most common form of cancer in women in both developing and developed countries. It is also the principal cause of death from cancer among women globally. Nutraceuticals, basically plant derived components are being used for the prevention and treatment of many diseases, including cancer. Heparan sulfatase-2 (hsulf-2) is a newly isolated oncoprotein, highly expressed in MCF-7 breast cancer cell line and inactivation of this protein possibly may prevent/impede the progression of the cancer. Many nutraceuticals viz. turmeric, ginger, soya and bael fruit extract as a whole and pure components curcumin and zerumbone have been studied in this report. Barring zerumbone, these nutraceuticals significantly inhibited the oncoprotein heparan sulfatase-2 (hsulf-2) activities isolated from MCF-7 breast cancer cell line, with an IC50 value at micro molar levels, indicating that these could be potential anticancer components. Curcumin inhibited cell proliferation with an IC50 value of 37.5 Î¼M, subsequently induced apoptosis of breast cancer cell line. In conclusion, the findings of the present study may provide a basis for further study of these nutraceuticals in the treatment of breast cancer.
Inhibitory Effect of Soybean Seed Extracts on Human Salivary Amylase: An in vitro Study
Authors: Gowda Thippeswamy Thippande , M. J. Shilpashree, , Goud Busineni Jayasimha , V. Dwarakanth , Sannaningaiah Devaraja
Published: November 2022

Enzymes are biological catalysts that accelerate the rate of metabolic reactions. Amylases are the class of hydrolase, split the (1-4) glycosidic bonds of polysaccharides into glucose or maltose. Salivary and pancreatic Î±-amylases share 92 % of analogy in their catalytic region. In diabetic condition, Î±-amylases become a major challenge in managing postprandial hyperglycemia. Natural inhibitors have been well-known to treat diabetes and were accounted to contain compounds with anti Î±-amylase activity. Soybean has been reported to have anti-diabetic activity because of its rich phytochemical content. The aim of the present study is to examine the in vitro inhibitory effects of aqueous, methanol and acid methanol extracts on the salivary amylase activity. Soybean seeds were procured from the Chikkapet market of Tumakuru, Karnataka State, India. Salivary amylase activity was estimated by the DNS method using maltose as standard. Amylase activity was found to be high at pH of 6.8 and a temperature of 37ð«Œ±C. Amylase inhibition exhibited by different solvent extracts of soybean has been recorded (92% in aqueous extract, 93% in methanol extract, 98% in acid methanol extract) and inhibition concentration (aqueous, 45.73 Î¼g; methanol, 34.26 Î¼g; acid methanol, 18.20 Î¼g).Total polyphenolic contents of various solvent extracts of soybean (0.29% in aqueous extract, 0.25% in methanol extracts and 0.27 % in acid methanol) might be the reason for the significant inhibition of amylase activity. Consequently, the results obtained in the present investigation can be considered as useful in controlling the digestion of complex sugars among the diabetic population by influencing the catalytic activity of salivary amylase.
Effect of Different Drying Methods on Nutritional and Functional Properties of Onion Powder
Authors: Kumari Aparna , Gautam Garima , Chauhan Anil Kumar , Singh Meenakshi , Singh Arshya
Published: November 2022

Onion is one of the most important vegetables used as a food ingredient and spice due to its flavor, aroma and pungency. Chemical composition of onion revealed that it contains vitamins, carbohydrates, proteins, minerals, dietary fiber, some cysteine derivatives and phenolic compounds. It has many medicinal benefits like wound healing, growth-inhibition of microbial and tumor cells, reduction of cancer risk, protection against cardiovascular diseases and diabetes and anti-inflammatory properties. However, post harvest loss during storage remains a major challenge for food researchers. To prevent price hikes and increase the shelf life of onion, preservation is a crucial step. The present study was conducted to evaluate the effect of the sun, tray, vacuum and freeze-drying treatment on the nutritional, functional and sensory acceptability of onion powders. The result indicates that the nutritional, color, texture, rheological and rehydration ratio of freezedried onion powder were better than other drying processes. Volatile compounds retain in lyophilized onion powder. However, they may be readily lost during other drying processes. Based on the micro-structure analysis of onion powder, the freeze-dried powder was found intact and porous cell. There was no leak of solute concentration. It can be concluded that among all drying methods, freeze-drying is considered the best method to preserve onions in various form like powder, flakes and was well accepted by the sensory panel.
Bioactive Compounds and Nutritional Profile of Fresh and Freeze-Dried Palmyra Palm Tender Fruit Endosperm (Borassus flabellifer)
Authors: S. K. Mathanghi , S. Kanchana , V. Perasiriyan , G. Hemalatha , C. V. Vanniyarajan , K. Kumutha
Published: November 2022

Palmyra palm Tender Fruit Endosperm (PTFE) is highly perishable and has to be consumed within few hours from harvest. Freeze drying was employed to enhance the shelf life and it was experimented against fresh PTFE for its bioactive and nutritional components. Antioxidant capacities in terms of DPPH and FRAP were analyzed and correlated with total phenols. GC-MS observation depicted the presence of bioactives such as octadecenoic acid, ricinoleic acid, n-hexadecanoic, sitosterol, stigmasterol, n-nonadecanol-1 and Cycloartenol in freeze-dried PTFE that possess good health effects. Nutritional evaluation conducted showed satisfying results and freeze-dried PTFE was microbiologically safe till one year of storage at ambient temperature and the samples were free from Salmonella, Staphylococcus spp, Clsotridium spp. Sensory scores portrayed no significant differences in terms of colour and appearance, flavor, taste and over all acceptability during one year of storage.
Quality Evaluation of Value Added Cookies
Authors: G. Suba , A. Thirumani Devi
Published: November 2022

Food supplementation is one of the most effective methods of promoting health and preventing or combating health problems, to reach some or all population. Supplementary foods were formulated on the basis of low cost, locally available foods, familiar to home maker and easy for preparation. Hence the present study was initiated to develop an iron and calcium rich health mix cookies. Cookies were prepared using the health mix which scored highest in terms of sensory evaluation and also had high level of calcium content. Sensory evaluation, nutrient content and calculation of cost effectiveness were done. The physical characteristics like weight, width, diameter, thickness and spread factor were determined. The physical characteristics were measured. The mean values of the standard and formulated cookies were different in the proximate principle composition and mineral content. The iron, calcium, magnesium and vitamin B-6 levels of formulated cookies were higher than the standard cookies. It was also noted that the moisture content of the standard cookies was 5.15 per cent and that of formulated cookies was 2.084 per cent. The moisture content of the formulated cookies was lower than the standard cookies as the sprouted ragi enhanced the reduction in moisture content in the flour. The protein content of the formulated cookies was 13 g which was slightly higher than standard cookies (10.2 g). This was attributed to the incorporation of high protein ingredients like soya, horse gram and roasted Bengal gram dhal in the formulated cookies. The fat content of the formulated cookies (20.0 g) was lower than the standard cookies with fat content of 35 g. The carbohydrate content of the formulated cookies (22.8 g) was much lower than the standard cookies (72 g). This is due to the incorporation of pulses, oil seeds which replaced some of the carbohydrate content in the cookies. From the overall acceptability, it was clear that only a slight difference was noted between the standard and formulated cookies.
Isolation, Identification and Free Radical Scavenging Potential of Acetogenin Rich Fractions from Annona muricata Leaves
Authors: Ilango Suganya , Jayachandran Priyanka , Nirmaladevi Ramalingam
Published: November 2022

Herbal extracts are indicative of the most important areas of traditional medicine in the world. In order to establish their potential as a source of phytomedicine, the study of medicinal plants is important to facilitate the proper use of herbal medicine. Annona muricata L. commonly known as Soursop belongs to the family Annonaceae. The active constituents present in the plant have preventive effects for various diseases. "Acetogenins” are powerful phytochemicals present in the Annona muricata. These compounds collectively have shown antitumor, parasiticidal, pesticidal and antimicrobial activities. The objective of the present study is to isolate, identify acetogenin rich fraction from Annona muricata leaves and to evaluate the capacity of free radical scavenging. This evidence stated that acetogenin rich fraction could be isolated from Annona muricata leaves and this important phytochemical compound was easily identified by using kedde's reagent. All the four fractions (F1C, F2C, F3C and F4C) tested for radical scavenging activity possess considerable scavenging activity, among the extracts tested F4C fraction exhibited highest scavenging activity.
Pre-Lacteal Feeding Practices: An Infraction of Nutritionally Secured and Healthy Generations
Authors: Katiyar Nidhi , P. A. Raajeswari
Published: November 2022

Various studies have emphasized the role of breast feeding in the prevention of wide range of infancy infections. But initiation of breast feeding is hindered by the cultural practices of Pre-Lacteal Feeding (PLF). In India this practice of giving pre-lacteal feeds cut across all the communities as it is considered to have a positive effect on child's Gastrointestinal (GI) health and intellectual growth. However, PLF has a detrimental effect on the child's growth and development as it delays initiation of breastfeeding and prevents initial bonding between the mother and the baby. Evidently Infants who receive PLF are more likely to be malnourished. In Karaikal, practice of PLF is very common. Hence it becomes imperative to assess the prevalence of PLF practices. The objectives of the study included assessment of PLF practices, types of PLF and delineate the factors associated with same among the working lactating mothers. Locale of the study was Karaikal, Puducherry. A sample size of 427 lactating working mothers using non-probable purposive sampling (0-12months) was chosen. To elicit information a pre-designed, pre-tested, semi-structured questionnaire was used. The data obtained was statistically analysed and showed prevalence of PLF practices among 47% of the mothers. 29% of the mothers gave sugar water to the newborns. Other PLFs included omam water (carom seeds), cow's milk, plain water, religious water, jaggery with honey, castor oil, mashed dates, mercury etc. 31% mothers cited traditional cultural practice running through generations as the reason behind giving pre-lacteal feedings, whereas other reasons included cleansing the GI tract (14%) and better suckling reflex (22%) etc. It may be concluded that PLF practices are one of the many faulty feeding practices prevalent in Karaikal, which are a major infraction of optimum growth and development. Hence there is an emergent need to educate mothers regarding ill effects of pre lacteal feeding along with benefits of colostrum, early initiation of breastfeeding and exclusive breastfeeding which can reduce the chances of morbidity and mortality in infants and may thus lay foundation for nutritionally secured and healthy generations.
Development and Standardization of Mango Leaf Incorporated Health Mix
Authors: S. Udhaya Geetha , S. Thilakavathy
Published: November 2022

With increase in diabetes and non communicable diseases and changing diet and lifestyles, it is essential to realize food anthropology. Millets plays an important role in human health. It is low calorie and has easily digestible components. Millets are small seeded grasses that are tough and grow well in dry zones as rain-fed crops, under marginal conditions of soil fertility and moisture in semi dry tropic area. They are highly nutritious, non-glutinous and not acid forming foods. Millets release lesser percentage of glucose compared to rice. Intake of fiber and antioxidant rich millets may promote the human health. In addition to millets, mango leaves have antioxidant properties and control the degenerative diseases like diabetes mellitus, asthma and so forth. The present study aims to utilize the mango leaves and millets to improve human health. The objective of the study is to develop healthy diet including millets, pulses and nuts. Some easily available millets, pulses and nuts were selected to formulate health mix. Mango leaves powder was incorporated in health mix in the ratio of 5, 10 and 15%. The acceptability trial was conducted organoleptically to standardize the health mix. Nutrient present in standardized health mix incorporated with mango leaves powder was analysed. The formulated health mix was prepared as porridge to evaluate the acceptability. Based on the organoleptic evaluation 5% of mango leaves powder incorporated health mix was highly acceptable. Nutrient analysis showed that standardized health mix with mango leaves powder was rich in macronutrients and micronutrients. The study reveals that easily available and low cost millets, pulses have more nutritional properties. There is need to propagate traditional millet based recipes with value addition phytonutrient rich leaves like mango.
Nutritional Profile of Adult Men (35-55 years), Energy Balance and Impact of Nutrition Education on their Nutritional Knowledge
Authors: R. D. Sathya Suba , S. Angeline Esther Preethi , K. M. Preethi Selvarani
Published: November 2022

Two hundred adult men between 36 and 55 years were selected for the assessment of their nutritional status. Information pertaining to socio economic status, anthropometric measurement, clinical profile and dietary pattern was collected using interview schedule. Energy costs of the activities were also collected. Information on the dietary nutrient intake was collected using 3-day dietary recall method. Anthropometric measurements namely height, weight, BMI and waist hip ratio were analyzed using standard procedures. Data was statistically analyzed. Results show that a greater percentage of the selected adult men were involved in moderate activity and belonged in middle income group. The educational qualification showed that 66% have completed school. The greater percentages of the selected subjects were from nuclear family. Most of the subjects were of normal height when compared with reference value. BMI revealed that forty nine percent were normal, 30% were overweight and 21% were obesity. Most of the selected subjects had WHR greater than 1. The food habits showed that majority of them were non vegetarians. Consumption of green leafy vegetables and fruits was less. On the contrary rice, wheat, red gram dhal were consumed daily. Most of the selected subjects mean nutrient intake was deficit when compared to RDA. The results of energy balance study showed that mean positive energy balance was 2098.2±90 kcal in the selected subjects. Nutrition education was given by power point, charts, pamphlets and a low energy snack was formulated and demonstrated used in the nutrition education programme. Results of paired t-test done shows that the nutrition education was effective (t = 3.84) and helped in improving the nutrition knowledge. The formulated product contains high amount of fibre. There is a need for educating these subjects on the right type and quantity of foods, higher intake of fibre rich foods, as well as the importance of regular physical activity to combat obesity.
Identification of Minerals and Phytochemicals Present in Commercial Ilavangadhi Chooranum Used to Treat Rheumatoid Arthritis
Authors: S. Kiruthika , V. Sharulatha , S. Kasthuri
Published: November 2022

Rheumatoid arthritis is an autoimmune disease which is chronic in nature. It is one of the major diseases that affect the world’s population. Siddha medicine system is one of the traditional medicines of Tamil Nadu. Siddha drugs are prepared from herbs and minerals of natural origin, hence may be considered as a nutraceutical. Ilavangadhi Chooranum is a poly herbo mineral drug used to treat rheumatoid arthritis. Identification of the minerals and phyto constituents in the formulation will help to improve the quality of the drug and scientifically relate the drug action with the constituent’s present. Hence the study was carried out to characterize the siddha formulation Ilavangadhi Chooranum by EDAX, XRD, SEM, UV, IR and GC-MS. The present investigation discovered that the primary elements present in the drug are magnesium and potasium as well as phytochemical constituents curcumin, zingerone, gingerol, penere and geronial.
A Study on Dietary and Life Style Behaviors of Selected Type II Diabetic Subjects of Coimbatore
Authors: N. Rajeswari , V. Premala Priyadharshini
Published: November 2022

India comprises of largest population of diabetics. Biomarkers, psychosocial and lifestyle are the risk indicators of type 2 diabetes mellitus. To hold back the onward progression of the disease among type 2 diabetic populations early screening for anthropometric and biochemical profiling and life style modification is the need of the hour. Hence with this, the objective of the paper is to explore the association between life style behaviour and biomarker in selected type II diabetic patients in Coimbatore. Five hundred type-II diabetic patient both male (237) and female (263) between the age group of 35-45 years were purposively selected for the conduct of the study. Using a well structured interview schedule the background information, medical history life style and dietary pattern were elicited. Anthropometric measurements, apart from biochemical analysis (fasting blood glucose, post prandial and lipid profile), assessment of diabetic specific Biomarker for HbA1c was done using standard procedures for all the selected 500 type II diabetic patients. The result shows that more than 50% of both male and female Type II diabetic subjects showed uncontrolled Post Prandial Glucose level (PPBS) and Glycosylated Haemoglobin (HbA1C) level, less than 35% of Type II diabetic subjects showed unsatisfactory Fasting Glucose level (FBS).
Clinical effects of combined anteversion and offset on postoperative dislocation in total hip arthroplasty
Authors: Matsuda Kenta , Hidaka Ryo , Nakamura Shigeru , Nakamura Masaki , Kawano Hirotaka
Published: November 2022

Background
Implant impingement and soft tissue tension are factors involved in dislocation after total hip arthroplasty (THA). Combined anteversion (CA) has been used as an indicator for implant placement; however, placing implants optimally remains challenging. Moreover, the effect of changes in offset on dislocation remains unclear. We aimed to clarify the effects of postoperative CA and pre- and postoperative changes in offset on dislocation.
Methods
We included patients who underwent primary cementless THA performed between 2013 and 2020. The mean values of CA and offset in the dislocation and non-dislocation groups were compared. The CA values within ± 10% of the recommended values were defined as good CA, and those outside the range were defined as poor CA. The dislocation rates in the good and poor CA groups and in the groups with and without increased offset were compared.
Results
A total of 283 hips were included. The mean values of CA in the dislocation and non-dislocation groups were significantly different (p < 0.001). The dislocation rate was significantly lower in the good CA group (p < 0.05). The dislocation rates in the groups with and without increased total offset were 0.5% and 4.3%, respectively (p = 0.004). There were no dislocations in patients with good CA and increased offset.
Conclusions
The dislocation rate was significantly lower when implants were placed within ± 10% of the recommended CA value. Our results suggest that dislocation can be avoided by placing the implant in the good CA range and considering the increase in total offset on the operative side.
A Comparative study of Posterior cingulate metabolism in Patients with Mild Cognitive Impairment due to Parkinson’s Disease or to Alzheimer’s Disease
Authors: Huang Mingming , Cai Xi , Zhang Yong , Pu Wei , Gao Bo , Yu Hui
Published: November 2022

Few comparative studies exist of metabolic brain changes in cognitive impairment among neurodegenerative illnesses. In this study, we compared posterior cingulate (PCC) metabolic abnormalities in patients with mild cognitive impairment (MCI) due to Parkinson’s disease (PD) and to Alzheimer’s disease (AD) as measured by proton magnetic resonance spectroscopy (1H-MRS). Thirty eight patients with idiopathic PD, including 20 patients with mild cognitive impairment (PDMCI), 18 patients with normal cognitive (PDN), 18 patients with probable mild cognitive impairment (ADMCI), and 25 healthy older controls (HC) underwent PCC1H-MRS scans. Compared with controls, patients with PDMCI exhibited significantly reduced concentration of N-acetyl aspartate (NAA) and total Creatine (tCr), while patients with ADMCI exhibited significantly increased concentration of myo-inositol (Ins), and reduced NAA/Ins ratio. There was reduced concentration of NAA, Ins and tCr in PDMCI compared with ADMCI. No significant metabolic alteration was found in PDN subjects. Besides, ROC analysis revealed that the concentration of tCr could differentiate PDMCI from PDN with an AUC of 0.71, and the level of NAA/Ins ratio could differentiate subjects with MCI from normal cognitive controls with an AUC of 0.74. Patients with PDMCI and ADMCI exhibited distinct PCC metabolic1H-MRS profiles. Findings suggest that cognitively normal PD patients with low NAA, tCr in the PCC might be at risk of preclinical PDMCI, and also the Ins and/or NAA/MI ratio in the PCC should be reconsidered as a possible biomarker of preclinical MCI in clinical practice. So, comparison of PCC1H-MRS profiles of cognitive impairment among neurodegenerative illnesses may provide useful information for better defining the disease process and elucidate possible treatment mechanisms.
A Postsurgical Prognostic Nomogram for Patients with Lymph Node Positive Rectosigmoid Junction Adenocarcinoma
Authors: Yanlong WU , Yibing Wang , Yunxiao Wu
Published: November 2022

Objective: The definition of rectosigmoid junction (RSJ) is still in debate. The treatment and prognosis of patients with rectosigmoid junction cancer (RSJC) and positive lymph nodes (PLN-RSJCs) are mostly based on the American Joint Committee on Cancer (AJCC) staging system. Our study aims to assist clinicians in creating a more intuitive and accurate nomogram model for PLN-RSJCs for the prediction of patient overall survival (OS) after surgery.
Methods: Based on the Surveillance, Epidemiology, and End Results (SEER) database, we extracted 3384 patients with PLN-RSJCs and randomly divided them into development (n=2344) and validation (n=1004) cohorts at a radio of 7:3. Using univariate and multivariate COX regression analysis, we identified independent risk factors associated with OS in PLN-RSJCs in the development cohort, which were further used to establish a nomogram model. To verify the accuracy of the model, the concordance index (C-index), receiver operating characteristic (ROC) curves, calibration curves, and an internal validation cohort have been employed. Decision curve analysis (DCA) was used to assess the clinical applicability and benefits of the generated model. Survival curves of the low- and high-risk groups were calculated using the Kaplan–Meier method together with the log-rank test.
Results: Age, marital, chemotherapy, AJCC stage, T and N stage of TNM system, tumor size, and regional lymph nodes were selected as independent risk factors and included in the nomogram model. The C-index of this nomogram in the development (0.751;0.737-0.765) and validation cohorts (0.750;0.764-0.736) were more significant than that of the AJCC 7th staging system (0.681; 0.665-0.697). The ROC curve with the calculated area under the curve (AUC) in the development cohort was 0.845,0.808 and 0.800 for 1-year, 3-year and 5-year OS, AUC in the validation cohort was 0.815,0.833 and 0.814 for 1-year, 3-year and 5-year, respectively. The calibration plots of both cohorts for 1-year,3-year and 5-year OS all demonstrated good agreement between actual clinical observations and predicted outcomes. In the development cohort, the DCA showed that the nomogram prediction model is more advantageous for clinical application than the AJCC 7th staging system. Kaplan-Meier curves in the low and high groups showed significant differences in patient OS.
Conclusions: We established an accurate nomogram model for PLN-RSJCs, intended to support clinicians in the treatment and follow-up of patients.
Ectopic Expression of Jatropha curcas JcTAW1 Improves the Vegetative Growth, Yield, and Drought Resistance of Tobacco
Authors: Peng Qingyan , Liu Chang , Zou Zhurong , Zhang Mengru
Published: November 2022

Jatropha curcas is a promising alternative bio-energy resource. However, underrun limited its broad application in the industry. Luckily, TAW1 is a high-productivity promoting gene that increases the lateral branches by prolonging the identification of inflorescence meristems to generate more spikes and flowers. In the current study, we introduced the Jatropha JcTAW1 gene into tobacco to depict a complete functional profile of the JcTAW1. Ectopic expressed JcTAW1 increased the lateral branches and ultimate yield of the transgenic tobacco plants. Moreover, the JcTAW1 lines observed a significantly higher plant height, longer roots, and better drought resistance. We performed RNA sequencing and weighted gene co-expression network analysis to determine which biological processes are affected by aberrant mutations in JCTAW1. We conclude that two up-regulated genes affect glucose metabolism and cell wall biosynthesis, and five down-regulated genes are involved in the negative regulation of DNA repair and TOR signaling. Biological processes such as carbon metabolism, cell wall biosynthesis, and ionization transport strongly affect the abnormal expression of JCTAW1. These findings indicate that JcTAW1 might drive the energy stream flowing to boost growth in three ways: (1) directly strengthening the energy metabolism cell proliferation; (2) improving the nutrient status by enhancing ion transport processes and releasing the TOR pathway from the negative regulation; (3) suppressing the DNA repair system to facilitate the cell proliferation.