bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of IL-4 and IL-1 Ra Gene Polymorphisms with the Risk of Bladder Cancer
Authors: POLAT Fikriye , BİNGÖL Günsel , BUDAK DİLER Songül
Published: August 2022

The aim of this study is to evaluate the association of interleukin-4 (IL-4) gene intron 3 and interleukin-1 receptor antagonist (IL-1Ra) gene intron 2 variable number tandem repeat (VNTR) polymorphisms with bladder cancer (BC) susceptibility in Turkish population. A total of 75 BC patients and 126 healthy controls were included in this case-control study. Genotyping for the interested polymorphisms were analyzed through polymerase chain reaction (PCR). The strength of association between both IL-4 and IL-1Ra gene VNTRs and BC susceptibility was estimated utilizing odds ratio (OR) with corresponding 95% confidence interval (CI). In the study, no statistically significant differences were determined in the allele distributions for either in IL-4 gene intron 3 VNTR (OR= 1.33; CI 0.704-2,41, p=0.390) or in IL-1Ra gene intron 2 VNTR polymorphisms (OR= 0.890; CI 0.569-1.394, p=0.346) between BC patients and control groups. The genotype distributions of IL-4 gene were estimated for RP1/RP2 (OR= 1.55; CI 0.11-7.74, p = 0.590) and RP1/RP1 (OR= 2.08; CI 0.48-9.06, p = 0.320), found no difference between BC and control groups. The genotype distributions of IL-1Ra gene were estimated for 2L (OR= 1.401; CI 0.753-2.610, p = 0.287) and 22 (OR=0.908; CI 0.252-3.276, p = 0.883) and found no difference between BC and control groups. This study suggest that there were no statistically significant differences determined either in genotype or allele distributions between BC patients and control groups for both IL-4 intron 3 VNTR and IL-1Ra intron 2 VNTR polymorphisms in Turkish population and therefore there was no association of these variants with BC risk in this population.
Investigation of inhibition effect of folic acid (vitamin B9) on angiotensin-converting enzyme activity purified from human plasma
Authors: BAŞ Zehra
Published: August 2022

Inhibition of the angiotensin-converting enzyme (ACE, EC 3.4.15.1) is one of the most important hypertension treatments. Here, ACE was purified from human plasma with affinity chromatography. The purity and molecule weight of ACE were identified utilizing the SDS-PAGE and
viewed in two bands at around 60 kDa and 70 kDa on the gel. KM and Vmax constants from the Lineweaver-Burk graphic were computed to be 0.6 mM and 175.44 (µmol/min).mL-1 , respectively. The effects of folic acid (vitamin B9) on purified ACE were studied. Folic acid on purified ACE demonstrated an inhibitory efficacy. The IC50 value for folic acid was calculated to be 127.94 µM.
Kind of inhibitory and Ki constant for folic acid were defined. The kind of inhibitory for folic acid was
found as non-competitive inhibitory. Ki constant was computed to be 226.59 µM for folic acid. In this
study, it was concluded that folic acid, which shows an inhibitor efficacy on ACE, may have both therapeutic and protective impacts against hypertension.
Applications of soft computing techniques for prediction of pollutant removal by environmentally friendly adsorbents (case study: the nitrate adsorption on modified hydrochar)
Authors: Divband Hafshejani Laleh , Naseri Abd Ali , Moradzadeh Mostafa , Daneshvar Ehsan , Bhatnagar Amit
Published: August 2022

Artificial intelligence has emerged as a powerful tool for solving real-world problems in various fields. This study investigates the simulation and prediction of nitrate adsorption from an aqueous solution using modified hydrochar prepared from sugarcane bagasse using an artificial neural network (ANN), support vector machine (SVR), and gene expression programming (GEP). Different parameters, such as the solution pH, adsorbent dosage, contact time, and initial nitrate concentration, were introduced to the models as input variables, and adsorption capacity was the predicted variable. The comparison of artificial intelligence models demonstrated that an ANN with a lower root mean square error (0.001) and higher R2 (0.99) value can predict nitrate adsorption onto modified hydrochar of sugarcane bagasse better than other models. In addition, the contact time and initial nitrate concentration revealed a higher correlation between input variables with the adsorption capacity.
Review of the use of cross iron in reinforced concrete column as an alternative to shoes column
Authors: Army B. , Sujahtra I. Wayan , Ramia I. Nyoman , Sutapa I. Ketut
Published: August 2022

Column shoe is the lower end of the column as high as (50-70) mm which is casted first from the column above it to make it easier to determine the column dimensions, determine the shape of the column cross section, and determine the position of the column. Column shoes Together with the formwork iron stack, clamping the formwork and making it easier to install the column formworkColumn shoes from site mix concrete have a weakness in terms of the concrete being non-uniform with the column concrete above it is feared to have problems with the bending moment, Mu, at the end of the column and the normal force, Pu Column shoes made of reinforced concrete are more practical, more economical and simpler and save project execution time, there is no problem with bending moments and normal forces acting on the column because the quality of the column concrete is uniform with the quality of the column shoes and cast at the same time.
Predicting Abnormalities in Laboratory Values of Patients in the Intensive Care Unit Using Different Deep Learning Models: Comparative Study
Authors: Ayad Ahmad , Hallawa Ahmed , Peine Arne , Martin Lukas , Fazlic Lejla Begic , Dartmann Guido , Marx Gernot , Schmeink Anke
Published: August 2022

Background

In recent years, the volume of medical knowledge and health data has increased rapidly. For example, the increased availability of electronic health records (EHRs) provides accurate, up-to-date, and complete information about patients at the point of care and enables medical staff to have quick access to patient records for more coordinated and efficient care. With this increase in knowledge, the complexity of accurate, evidence-based medicine tends to grow all the time. Health care workers must deal with an increasing amount of data and documentation. Meanwhile, relevant patient data are frequently overshadowed by a layer of less relevant data, causing medical staff to often miss important values or abnormal trends and their importance to the progression of the patient’s case.

Objective

The goal of this work is to analyze the current laboratory results for patients in the intensive care unit (ICU) and classify which of these lab values could be abnormal the next time the test is done. Detecting near-future abnormalities can be useful to support clinicians in their decision-making process in the ICU by drawing their attention to the important values and focus on future lab testing, saving them both time and money. Additionally, it will give doctors more time to spend with patients, rather than skimming through a long list of lab values.

Methods

We used Structured Query Language to extract 25 lab values for mechanically ventilated patients in the ICU from the MIMIC-III and eICU data sets. Additionally, we applied time-windowed sampling and holding, and a support vector machine to fill in the missing values in the sparse time series, as well as the Tukey range to detect and delete anomalies. Then, we used the data to train 4 deep learning models for time series classification, as well as a gradient boosting–based algorithm and compared their performance on both data sets.

Results

The models tested in this work (deep neural networks and gradient boosting), combined with the preprocessing pipeline, achieved an accuracy of at least 80% on the multilabel classification task. Moreover, the model based on the multiple convolutional neural network outperformed the other algorithms on both data sets, with the accuracy exceeding 89%.

Conclusions

In this work, we show that using machine learning and deep neural networks to predict near-future abnormalities in lab values can achieve satisfactory results. Our system was trained, validated, and tested on 2 well-known data sets to ensure that our system bridged the reality gap as much as possible. Finally, the model can be used in combination with our preprocessing pipeline on real-life EHRs to improve patients’ diagnosis and treatment.
Effects of high and low-to-moderate intensity exercise during (neo-)adjuvant chemotherapy on muscle cells, cardiorespiratory fitness and muscle function in women with breast cancer: Protocol for a randomized controlled trial (Preprint)
Authors: Vikmoen Olav , Wiestad Tor Helge , Thormodsen Inger , Nordin Karin , Berntsen Sveinung , Demmelmaier Ingrid , Strandberg Emelie , Raastad Truls
Published: August 2022

UNSTRUCTURED

Background: (Neo-)adjuvant chemotherapy for breast cancer is effective but has deleterious side effects on muscle tissue resulting in reduced skeletal muscle mass, muscle function and cardiorespiratory fitness. Various exercise regimens during cancer treatment have been shown to counteract some of these side effects. However, no study has compared the effect of high intensity training vs. low-to moderate intensity training on muscle tissue cellular outcomes and function in breast cancer patients during chemotherapy. The aim of the present sub-study within the Phys-Can consortium, is to evaluate and compare the effects of high and low-to-moderate intensity exercise on muscle cellular outcomes, muscle function and cardiorespiratory fitness in women with breast cancer undergoing (neo-)adjuvant chemotherapy. We further aim to investigate if chemotherapy including taxanes have different effect in muscle than taxane-free chemotherapy.
Methods: Eighty women, recently diagnosed with breast cancer scheduled to start (neo-)adjuvant chemotherapy will be randomized to a combination of strength and endurance training, either at high intensity or at low-to-moderate intensity. Testing of muscle function and cardiorespiratory fitness and collection of muscle biopsies from m. vastus lateralis will be performed before the first cycle of chemotherapy (or, when not possible, one week after) (T0), halfway through chemotherapy (T1), and after completion of chemotherapy (T2). It is estimated that approximately 50% of the participants will be willing to take muscle biopsies. To separate the effect of the treatment itself, a usual care group with no supervised training will also be included, and in this group testing and collection of muscle biopsies will be performed at T0 and T2 only.
Results: Inclusion started in December 2016 and the last participant is expected to complete the intervention in December 2022.
Discussion: The present study will generate new knowledge about the effects of different training intensities for women with breast cancer during chemotherapy treatment. It will give further insight into how chemotherapy affects muscle tissue and how physical training at different intensities may counteract treatment side effects in muscle. The results from this study will inform the development and refinement of exercise programs that are effective and compatible with multidisciplinary management of breast cancer.
Social Dynamics and Discourse Moves: A Closer Look into a Twitter-facilitated Professional Learning Community (Preprint)
Authors: Zheng Binbin , Beck Dallaghan Gary , Wang Zilu
Published: August 2022

BACKGROUND

Twitter is increasingly used by professionals, in part because of its potential to support easy and rapid communication among like-minded people. It is also used widely by educators to support the establishment of professional learning communities.

OBJECTIVE

This study investigates social interactions and knowledge construction in synchronous online discussions using the Twitter hashtag #MedEdChat.
Three synchronous Twitter discussions on #MedEdChat during the early part of the COVID-19 pandemic were analyzed. First, social-network analysis was conducted to capture the social interactions among their participants and network dynamics. Additionally, content analysis was employed to more closely examine the nature of tweets posted on #MedEdChat, including social-, cognitive-, and moderation-related tweets.

METHODS

Three synchronous Twitter discussions on #MedEdChat during the early part of the COVID-19 pandemic were analyzed. First, social-network analysis was conducted to capture the social interactions among their participants and network dynamics. Additionally, content analysis was employed to more closely examine the nature of tweets posted on #MedEdChat, including social-, cognitive-, and moderation-related tweets.

RESULTS

In all three networks, a small number of individuals dominated the discussion, while also serving as hubs for connections with others in more peripheral positions. Very few were isolated nodes who never interacted with others during the online discussions. Our content analysis suggested that parties to these discussions posted social-related posts the most, followed by cognitive-related ones. Social posts focused on others’ messages, continuing threads, issuing compliments and greetings, and expressing emotions. Cognitive-related posts, on the other hand, mostly focused on information exchange/sharing or asking content-related questions to promote discussion (i.e., triggering event).

CONCLUSIONS

By examining social dynamics and discourse moves in Twitter-supported online synchronous discussions using the #MedEdChat hashtag, this study found that Twitter has the potential to establish professional learning communities in which a few highly active individuals serve as portals for connections and interactions among all discussants. In addition, in such communities, social- and cognitive-related tweets could promote social interactions and knowledge construction.
The Usage of Digital Health Technology Among Older Adults in Hong Kong and the Role of Technology Readiness and eHealth Literacy: Path Analysis (Preprint)
Authors: Kim Seungmo , Chow Bik Chu , Park Sanghyun , Liu Huaxuan
Published: August 2022

BACKGROUND

Although digital health technologies (DHTs) help many people maintain a healthy life, including those of advanced age, these technologies are of little use to older adult populations if they are not being adopted in daily life. Thus, it is critical to identify ways to help older adults recognize and try new technologies and maintain their use of them to maximize the benefits of these technologies in a digital-based society.

OBJECTIVE

Our study aimed (1) to assess the current usage of DHT among older adults in Hong Kong and (2) to examine how high and low levels of eHealth literacy in this group affects the relationship between the Technology Readiness and Acceptance Model (TRAM) and attitudes and intention toward DHT.

METHODS

A total of 306 adults over 60 years of age in Hong Kong participated in this study. After conducting confirmatory factor analysis to validate the measurement model, the hypothesized model was tested using structural equation modeling.

RESULTS

Optimism was significantly related to perceived usefulness, while optimism, innovativeness, and discomfort were significantly associated with perceived ease of use. Both perceived usefulness and perceived ease of use were significantly linked to attitude toward the use of DHTs. Meanwhile, attitude significantly predicted usage intention. Additionally, the results revealed the differences in the relationships of the TRAM between participants with high and low levels of eHealth literacy. The influence of optimism and innovativeness on perceived ease of use was stronger for the higher-level group than for the lower-level group, and the influence of discomfort for the higher-level group was much weaker.

CONCLUSIONS

The findings provided partial support for the impact of eHealth literacy on encouraging older adults to use DHT and obtain health benefits from it. This study also suggests providing assistance and guidelines for older adults to narrow the aging-related technology gap and to further explore the associations of eHealth literacy, the TRAM, and actual behaviors.
Adsorption and release of soil P in andisols under organic and conventional vegetable farming system
Authors: Maritasari Aridinasty , Purwanto Benito Heru , Utami Sri Nuryani Hidayah
Published: August 2022

Phosphorous (P) is strongly adsorbed by soil components, such as soil organic matter and soil amorphous minerals in Andisols, which have been identified as an influential factor in adsorption and release of soil P. The aim of this study was to characterize the pattern of soil P adsorption and release in both organic and conventional vegetable farming systems in Merbabu Mountain area, Indonesia. Soil samples were collected from soil layers (0 cm to 20 cm and 20 cm to 40 cm) in organic and conventional farming systems. The result showed that the highest adsorption rate was found in organic farming systems at a depth of 20 cm to 40 cm. The lowest adsorption rate was found in conventional farming systems with low input of organic matter at a depth of 20 cm to 40 cm. A higher rate of P release was also found in organic farming systems with a low input of organic matter. It can be concluded that vegetable soils in organic farming systems are not only highly capable of adsorbing P but also capable of releasing P rapidly.
Anatomical characteristics of cocoa plant roots as affected by the levels of calcium fertilization
Authors: Lubis Sutan Tarmizi , Putra Eka Tarwaca Susila , Kurniasih Budiastuti
Published: August 2022

Cocoa plant (Theobroma cacao L.) is one of good annual crops grown in Indonesia. The disadvantages and advantages of Ca in plants can affect morphology and anatomy in plants. This research aimed to identify the effect of Ca on the anatomical performance of the roots of cocoa plants and determine the optimal dose of Ca for the anatomical characteristics of the roots of cocoa plant. The research was conducted at the cocoa plantation owned by PT. Pagilaran at North Segayung Production Unit, Tulis Subdistrict, Batang Regency, Central Java, in October 2019 – February 2021. The observation of root anatomy was carried out by making preparations, and the plant roots were taken destructively and sliced transversely. The field experiment was arranged using a single factor randomized complete block design. The treatments consisted of without fertilizer application and calcium fertilization at a dose of 100 g/tree/year, 200 g/tree/year, 300 g/tree/year, and 400 g/tree/year. The cocoa clone used was clone RCC 71. The results showed that an increase in the dose of CaCl2 fertilizer up to 400 g/tree/year was generally followed by an increase in the size of the xylem and phloem diameters, the thickness of the cork layer, the thickness of secondary cortex, and the diameter of the stele. The quadratic effect of the dose of CaCl2 fertilizer was observed only on the thickness of the root cambium tissues. Thus, it is necessary to conduct further research to determine the optimal dose of Ca fertilizer for the anatomical characteristics of cocoa roots.
Competitive adsorption of phosphate with sulfate, humic acid, and fulvic acid by allophane in different parent materials in Central Java
Authors: Fauziah Lilia , Hanudin Eko , Utami Sri Nuryani Hidayah
Published: August 2022

Andisol is a soil that has andic properties and develops from volcanic parent materials, especially ash. Andic soil properties are formed due to weathering of tephra or other parent materials that contain volcanic glass in large quantities. The main components of soil-forming Andisol are amorphous (short-range-order) minerals, such as allophane, imogolite, ferrihydrite, and Al/Fe-humus complexes. The existence of short-range-order minerals causes Andisol to have high P-tapping ability, but efforts to lower the amount of P plunged with organic and inorganic an-ons have not been widely studied. This study aimed to compare the ability of humic acid, fulvic acid, and sulfate in suppressing P adsorption by amorphous minerals from the Andisol of Mount Dieng, Merbabu, and Sumbing. The highest calculation of % ferrihydrite was found at the location of Mount Merbabu with a value of 3.05%, while the % allophane + imogolite was determined by the content of Sio in the ground. The calculation results showed that the highest was found at the location of Mount Sumbing with a value of 7.17%. Based on TEM analysis, Mount Sumbing has allophane diameter of 2.24 – 5.93 nm and the imogolite length of 24 – 187 nm.
Development of visual identity and positioning of a design agency based on archetypes
Authors: Bernardi Baronio Coralina , Munari Pagan Natália , Munari Pagan Karina
Published: August 2022

A company's brand is not just a name and logo, it is also the company's commitment to customers. Brand is a strategic asset, and therefore, when building a brand, the values, purpose, positioning, and personality of the company are also created. The psychology of archetypes understands the inner meaning of brands and products and helps marketers establish lasting concepts and identities. Archetypes are images, symbols, characters and myths that exist all over the world and transmit information in our collective unconscious. By using archetypes, brands have the ability to connect consumers' most basic emotions and motivations. Three archetypes were defined to develop three logos based on their concepts. The archetypes analyzed here are Mage, Jester, and Creator. A survey was carried out with the brand's target audience to find out if the logo was conveying the archetype's message and defined a positioning for the agency. The results obtained were that it is possible to develop a visual identity based on the concepts of archetypes and pass positive emotions and sensations through them.
A Review on Medicinal Plants Having Anticancer Properties of Northeast India and Associated Endophytic Microbes and their Future in Medicinal Science
Authors: Kalita Sanjib , Sarma Anindita , Hazarika Ankur , Hazarika Satarupa , Saikia Saranga Pani , Kalita Dibyajyoti
Published: August 2022

Human beings are affected by different diseases and suffer to different extents. Cancer is one of the major human disease and millions of people suffered from cancer and end their lives every year. Peoples are dependent on herbal medicines since prehistoric time especially from developing countries. It is very common to have different side effects of modern synthetic medicines; hence now-a-days importance of herbal medicines due to no or least side effects increases all parts of the world. But the major problems of using herbal medicines are that plants can produce very limited amount of medicinally important bioactive metabolites and they have very long growth periods. Therefore endophytes are the excellent alternative of plant derived metabolites. Endophytic microbes can synthesize exactly same type of metabolites as the plant produces. North East India is a treasure of plant resources; various types of medicinal plants are present in this region. Different types of indigenous tribes are inhabited in this region who used different plants in traditional system for treating various disease. But with increasing demand it is sometimes not sufficient to manage the demand of medicines, therefore for massive production endophytic study is crucial. In spite of having huge plant resources very limited endophytic studies are observed in this region. In this review, we studied different plants with their endophytes of NE India showing anticancer properties.
Production of Single Cell Protein from Fruit Waste
Authors: Shah Urja , Hajoori Dr. Murtaza
Published: August 2022

Abstract: The fast growing population of the world has led to an increased demand for protein rich foods. The conversion of fruit waste into single cell protein is an alternative solution to the worldwide protein deficiency and environmental pollution concerns. Dried cells of bacteria, algae, yeast and fungi which are rich in protein and could be used as dietary supplements are called single cell protein. In the present study single cell protein represent microbial cells grown in mass culture and harvested for use as protein source in foods and animal feed. Fruit waste was used as sole carbon source for preparation of fermentation on used for the growth of bacteria, fungi, algae and yeast. The increased incubation time of different fruits hydrolaysate enhanced the biomass yield and the protein formation within the cell. The bioconversion of fruit waste by microbial fermentation into single cell protein has potential use for solving the worldwide protein deficiency in food. The finding in this study indicated that fruit waste could serve as a good substrate for single cell protein production.
Experimental Study of the Physical Properties of Concrete Prepared by Partial Replacement of Cement with Alccofine, Metakaolite and GGBS
Authors: Ansari Nayyer , Bandewar Deepak Kumar
Published: August 2022

Abstract: Cement concrete is the most broadly used construction material in the world. Maintenance and repair work of concrete structures is an increasing problem involving the significant expenditure. As a result of study carried out worldwide, it has been made possible to process the material to satisfy more strong performance requirements, especially durability. To reduce the expenditure for making of concrete we should consider the industrial waste materials for partial replacement of cement with supplementary cementitious materials like alccofine, GGBS and meta-kaoline. We consider these materials because these are available at very low cost. For this purpose we prepared number of samples by the various mixes with variable percentage of these materials in the mix. After the selection of the mix on these prepared specimens we perform workability and compressive strength test in the laboratory. By these tests we come to know that when we replace cement by Alcofine up to 10% the compressive strength increases 414.53 but after this range of addition it starts reducing the strength. when we replace cement by GGBS up to 15% the compressive strength increases 421.40 but after this range of addition it starts reducing the strength and same when we replace cement by Meta-kaoline up to 10% the compressive strength increases 448.44 but after this range of addition it starts reducing the strength
Covid-19 pandemic awareness and coping strategies of cocoa farmers in Ondo State of Nigeria
Authors: Agulanna Foluso Temitope
Published: August 2022

The study investigated COVID-19 pandemic awareness and coping strategies of cocoa farmers in Ondo State of Southwestern Nigeria. Random sampling technique was used to select cocoa farmers in the study area. A total of fifty cocoa farmers (respondents) were purposively selected from Ile-Oluji/Oke-Igbo local government area of the state. Information was collected from the selected farmers with the aid of well-structured questionnaires and the data retrieved from forty-six cocoa farmers collected were analysed with descriptive statistics and chi-square analysis. The result of the analysis showed that 76.1% of the farmers are above the age of 41 years, 78.3% are males while 76.1% are married. Similarly, 78.3% of the cocoa farmers have 4-6 children in the household, 26.1% had secondary education, 43.5% have 16 to 20 years farming experience while 73.9% lived in condominiums or housing units where residents are herded together thereby predisposing them to the risk of the contagion. Most of the respondents (95.7%) had low income or sales during covid-19 pandemic, 78.3% ate food three times before covid-19 while 15.2% ate three times during the pandemic. 89.1% did not have enough food at home during the lockdown and 95.6% did not have enough money to buy food during the pandemic. Majority of the respondents (96%) were aware of the occurrence of COVID-19, 69.6% of the respondents coped by relying on less expensive food during the lockdown, 56.5% reduced their food consumption due to income loss, 63% reduced the number of meals eaten daily while 67.4% reduced the portion or size of meal daily during COVID-19. The chi-square test also showed that a significant relationship exists between farmers’ awareness and coping strategies to covid-19 as well as the quality and type of food they consumed.
Determination of tdh and trh Positive Vibrio alginolyticus Isolates from Black Mussel (Choromytilus meridionalis) in Aegean Sea coast of Turkey
Authors: Avsever Meriç Lütfi
Published: August 2022

Abstract: Vibrio alginolyticus is one of the important pathogens, especially found in bivalve mollusks and food poisoning in humans. The severity of food poisoning is directly proportional to the virulence genes of V. alginolyticus. Tdh-Related Hemolysin (trh) and Thermostable Direct Hemolysin (tdh) genes have an important place among the virulence genes found in V. alginolyticus. In this research, 17 V. alginolyticus were isolated from 17 orders (80.95%) of 21 sets of black mussels (Choromytilus Meridionalis) samples purchased from local divers in İzmir and Balıkesir regions. While trh gene was detected in 7 (42.17%) of 17 isolates, tdh gene was found in 6 (35.29%) and both trh and tdh genes were found in 2 (11.76%) isolates; no trh or tdh gene was found in 2 isolates (11.76%). The results of the study are also important in terms of public health. Black mussel is a product that is mainly consumed in coastal areas in Turkey and is mostly sold uncontrolled by mussel sellers. Vibrios with virulence genes can cause food poisoning, especially in summer. In addition, V. alginolyticus may be a tdh-trh reservoir for other vibrio species. To clarify this, more detailed research should be done with other vibrio species and other bivalve species.
A Case of IgG4-Related Pseudotumor in Larynx
Authors: Lee Min Hyuk , Hong Joon Pyo , Kim Tae Hwan , Jin Sung Min
Published: August 2022

IgG4-related disease is a fibroinflammatory condition by infiltration of IgG4-positive plasma cells that often presents as a tumorous lesion. This disease can affect nearly every organ system. After the pancreas, the head and neck region is second most common site for presentation of IgG4- related disease such as Mikulicz’s disease, Küttner tumor. The involvement of IgG4-related disease in laryngeal lesions is extremely rare. We have experienced a case of IgG4-related disease with pseudotumor formation in the larynx that is suggestive of malignancy in radiologic findings. But the pathology findings was finally confirmed as IgG4-related disease. Oral treatment with prednisolone was initiated, and the edematous mass reduced in size without permanent functional impairment of vocal fold mobility. We report our experience with a literature review.
Guidance to the Praat, a Software for Speech and Acoustic Analysis
Authors: Seong Cheol Jae
Published: August 2022

Praat is a useful analysis tool for linguists, engineers, doctors, speech-language pathologits, music majors, and natural scientists. Basic parameters including duration, pitch, energy and perturbation parameters such as jitter and shimmer can be easily measured and manipulated in the sound editor. When a more in-depth analysis is needed, it is recommended to understand the advanced menus of the object window and learn how to use them. Among the object window menus, vowel formant analysis, spectrum analysis, and cepstrum analysis can be cited as useful ones in the clinical field. The spectrum object can be usefully used for voice quality measurement and diagnosis of patients with voice disorders by showing the energy distribution according to frequency axis (domain). A cepstrum object is useful for speech analysis when periodicity of the sound object is not measurable. The low to high ratio obtained from the spectral object and the CPPs measured from the cepstrum object have attracted many researchers, and it has been proven that the CPPs measured in Praat are relatively excellent.
Phylogenetic Analysis of Mud Crab Scylla olivacea with Several Crustacean based on mRNA Encoding FAMeT
Authors: Sunarti Sunarti , Tahya Akbar Marzuki , Jamaluddin Ruqayyah
Published: August 2022

Penelitian sebelumnya telah berhasil mengisolasi, dan sekuens basa nukleotida mRNA penyandi FAMeT Scylla olivacea. Beberapa penelitian menuliskan bahwa urutan mRNA penyandi FAMeT memiliki perbedaan pada spesies krustasea. Tujuan penelitian untuk mengetahui jarak kekerabatan S. olivacea dengan krustasea lainnya berdasarkan sekuen mRNA penyandi FAMeT. Kesamaan sekuen mRNA penyandi FAMeT menunjukkan beberapa krustasea yang memiliki kemiripan dengan sekuen mRNA FAMeT S. olivacea. Analisis pohon filogeni menunjukkan adanya 2 klasterkekerabatan mRNA penyandi FAMeT S. olivacea pada cabang yang sama dengan 2 spesies kepiting lainnya: S. serrata dan S. paramamosain. Selain pada genus Scylla, ditemukan pula pada Portunus trituberculatus dan P. pelagicus serta udang sungai Macrobrachium rosenbergii. Temuan tersebut menunjukkan bahwa kepiting S. olivacea monofiletik dengan 2 kepiting bakau lainnya, yaitu rajungan serta udang sungai M. rosenbergii. Sehingga menggambarkan hubungan kekerabatan yang sangat dekat secara genetik. Sementara pada cabang ke 2 terdiri atas krustasea jenis udang-udangan seperti Homarus americanus, Cherax quadricarinatus, Fenneropenaeus merguiensis, Metapenaeus ensis dan Litopenaeus vannamei.
Feeding Frequency to Increase in Body Weight and Blood Chemical Levels of Local Goat
Authors: Hamid Padang , Zainal Zainal , Nirwana Nirwana , Mustafa Mustafa
Published: August 2022

Penelitian bertujuan mengetahui pertambahan bobot badan konsumsi bahan kering, efisiensi penggunaan bahan kering, kadar glukosa darah dan kadar urea darah kambing kacang yang diberi pakan dengan frekuensi berbeda. Organisme uji sebanyak 15 ekor kambing lokal betina berumur ±10 bulan dengan bobot badan 14–20 kg. Penelitian bersifat eksperimen menggunakan RAL dengan tiga perlakuan dan 5 ulangan. Perlakuan yang dicobakan adalah : P1 = Pemberian pakan 1,5% konsentrat dan 1,5% hijauan bahan kering diberikan satu kali pada pukul 07.00 WITA berdasarkan bobot badan; P2 = Pemberian pakan 0,75% konsentrat dan 0,75% hijauan bahan keringdiberikan pada pukul 07.00 WITA, pukul 13.00 WITA diberikan kembali 0,75% konsentrat dan 0,75% hijauan bahan kering berdasarkan bobot badan; P3 = Pemberian pakan 0,5% konsentrat dan 0,5% hijauan bahan kering diberikan pada pukul 07.00 WITA, dan pada pukul 13.00 WITAdiberikan 0,5% konsentrat dan 0,5% dan pukul 19.00 WITA diberikan 0,5% konsentrat dan 0,5% pada hijauan bahan kering berdasarkan bobot badan. Hasil penelitian ini menunjukkan bahwa frekuensi pemberian pakan tidak memberikan pengaruh terhadap konsumsi bahan kering dan kadar urea darah, namun pemberian pakan sebanyak 2 kali nyata meningkatkan pertambahan bobotbadan, efisiensi penggunaan ransum dan kadar glukosa darah kambing kacang.
Growth and Survival Rate Goldfish (Carassius auratus L.) in Various Dosages of Natural Feed Tubifex sp.
Authors: Risdawati  , Widiastuti Irawati Mei
Published: August 2022

Ikan mas koki (Carassius auratus L.) termasuk ikan hias air tawar yang populer dibudidayakan di Indonesia. Salah satu kendala dalam usaha budidaya ikan mas koki adalah biaya pakan yang tinggi (60-70%) dari total biaya produksi. Sumber pakan alami untuk ikan mas koki adalah cacing sutera yang mengandung kandungan  nutrisi yang cukup tinggi. Penelitian bertujuan mengetahui dosis cacing Tubifex sp. terbaik untuk pertumbuhan dan sintasan benih ikan mas koki (C. auratus L.). Penelitian dilakukan di Laboratorium Kualitas Air dan Biologi Akuatik, Fakultas Peternakan dan Perikanan, Universitas Tadulako selama 2 bulan (Januari - Maret 2020). Desain percobaan menggunakan  Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 4 kali ulangan. Perlakuan dalam penelitian adalah pemberian Tubifex sp. dengan dosis berbeda (A=6%; B=8%; C=10%; D=12%; E=14%). Variabel yang diukur meliputi pertumbuhan bobot mutlak, sintasan dan kualitas air. Data dianalisis dengan analisis ragam (ANOVA), dengan uji lanjut Beda Nyata Jujur (BNJ) menggunakan program aplikasi Excel 2010 dan Minitab 16.  Hasil penelitian menunjukkan bahwa pemberian pakan alami Tubifex sp. menunjukkan pertumbuhan bobot mutlak yang significan, namun tidak berpengaruh terhadap sintasan. Pertumbuhan mutlak benih ikan mas koki tertinggi yaitu pada pemberian pakan Tubifex sp. dengan dosis 12% sebesar 14,82±2,76 g dengan persentase sintasan sebesar 90,63%±6,25. Kualitas air (suhu, pH, oksigen terlarut dan amonia) masih sesuai dengan kebutuhan pertumbuhan benih ikan mas koki.
Effect of the Concentration of the Mushrooms Neurospora sp. and Fermentation Time on Dry Material Content, Crude Protein and Crude Fiber of Sludge Palm Oil
Authors: Hasmida  , Hasanuddin Asriani , Syahrir  , Aidah Nur
Published: August 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh interaksi level konsentrasi jamur Neurospora sp. dan waktu fermentasi terhadap kandungan bahan kering, protein kasar, dan serat kasar lumpur sawit. Penelitian ini menggunakan rancangan acak lengkap (RAL) pola faktorial 3x3 setiap perlakuan diulang 2 kali. Faktor pertama adalah level konsentrasi jamur (0%, 5%, 10%) dan faktor kedua adalah waktu fermentasi (48, 72, dan 96 jam). Hasil analisis ragam menunjukkan bahwa perlakuan interaksi antara level konsentrasi jamur Neurospora sp. dan waktu fermentasi lumpur sawit, berpengaruh sangat nyata (P<0,01) terhadap kandungan bahan kering dan protein kasar sedangkan pada kandungan serat kasar tidak berpengaruh nyata (P>0,05). Secara mandiri level konsentrasi dan waktu berpengaruh nyata terhadap kandungan bahan kering, protein kasar dan serat kasar. Nilai tertinggi bahan kering diperoleh pada kombinasi waktu 72 jam dan konsentrasi 10% (W2K10% = 66,323%) dan pada protein kasar yaitu waktu 96 jam dan konsentrasi 10% (W3K10% = 21,430%), sedangkan pada serat kasar terjadi penurunan. Penggunaan Neurospora sp. dengan konsentrasi dan waktu fermentasi yang berbeda dapat meningkatan kandungan bahan kering, protein kasar, dan menurunkan kandungan serat kasar lumpur sawit fermentasi.
Complete Silage of Forage Corn and King Grass to Weight Gain and Physiological Status of Goat and Sheep
Authors: Nirwana  , Wulan Sri , Zainal
Published: August 2022

Penelitian ini bertujuan untuk mengetahui pertambahan bobot badan, konsumsi bahan kering, efisiensi penggunaan bahan kering, suhu tubuh, frekuensi respirasi, dan frekuensi pulsus kambing Kacang dan domba lokal yang diberi silase komplit berbahan dasar hijauan jagung dan rumput raja. Ternak yang digunakan dalam penelitian ini berjumlah 12 ekor ternak kambing betina dan 12 ekor ternak domba umur ±10 bulan. Penelitian ini menggunakanRancangan Acak Lengkap (RAL) pola faktorial 2×2 dan diulang sebanyak 6 kali. Faktor pertama adalah jenis ternak (kambing dan domba). Faktor kedua terdiri atas dua jenis silase komplit yaitu P1 = Silase komplit berbahan dasar hijauan jagung dan P2 = Silase komplit berbahan dasar rumput raja. Hasil analisis ragam menunjukkan bahwa terdapat interaksi antara jenis ternak dan silase komplit terhadap konsumsi bahan kering ransum, namun tidak berpengaruh nyata terhadap pertambahan bobot badan, efisiensi penggunaan bahan kering ransum, suhu tubuh, frekuensi respirasi, dan frekuensi pulsus. Ternak kambing memiliki pertambahan bobot badan nyata lebih tinggi, namun suhu tubuh dan frekuensi pulsus lebih rendah dibanding ternak domba. Adapun konsumsi bahan kering, efisiensi penggunaan ransum dan frekuensi respirasi tidak menunjukkan adanya perbedaan yang nyata. Silase komplit tidak menunjukkan adanya perbedaan yang nyata terhadap pertambahan bobot badan, konsumsi bahan kering ransum, efisiensi penggunaan bahan kering ransum, suhu tubuh, frekuensi respirasi dan frekuensi pulsus.
Addition of Carrot Flour in Commercial Feed to Enhance Colour Brightness of Siamese Fighting Fish (Betta sp.)
Authors: Ansar  , Nasmia
Published: August 2022

Warna yang cerah merupakan salah satu daya tarik utama ikan hias. Semakin cerah warna ikan hias maka semakin tinggi nilainya. Salah satu usaha yang dilakukan untuk mendapatkan warna cerah yang merata pada ikan adalah pemberian pakan sumber karoten dan suplemen. Tujuan penelitian ini untuk mengetahui pengaruh penambahan tepung wortel pada pakan komersil terhadap tingkat kecerahan warna ikan cupang (Betta sp.) Penelitian dilakukan di Laboratorium Kualitas Air dan Biologi Akuatik, Fakultas Peternakan dan Perikanan, Universitas Tadulako mulai bulan Agustus-September 2020. Desain percobaan menggunakan Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 4 kali ulangan. Perlakuan dalam penelitian ini adalah penambahan tepung wortel pada pakan komersil untuk meningkatkan kecerahan warna ikan cupang (Betta sp.) A= Tanpa tepung wortel, B=24%, C=25% D=26%, E=27%. Hasil penelitian menunjukkan bahwa peningkatan warna yang tertinggi terdapat pada perlakuan E penambahan tepung wortel 27% memberikan peningkatan warna pada ikan cupang dengan skor rata-rata 7,1, kemudian diikuti perlakuan C=25% dengan skor 7,0, kemudian diikuti perlakuan D=26% dengan skor 6,7 kemudian diikuti perlakuan B=24%, dengan skor 6,5, sedangkan yang terendah terdapat pada perlakuan A tanpa penambahan tepung wortel dengan skor rata-rata 6,4.
Effect of Different Natural Feeds on Growth and Survival Rate of Tilapia Larvae (Oreochromis niloticus)
Authors: Tobigo Desiana Trisnawati , Hisra
Published: August 2022

Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan jenis pakan alami berbeda terhadap pertumbuhan dan kelangsungan hidup larva ikan nila (Oreochromis niloticus). Penelitian ini dilaksanakan pada bulan Desember 2020 bertempat di Laboratorium Budidaya Perairan, Fakultas Peternakan dan Perikanan, Universitas Tadulako, Palu. Larva yang digunakan berumur 7 hari. Penelitian ini didesain dengan menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari tiga perlakuan dan enam ulangan. Pakan yang digunakan berupa Moina sp., jentik nyamuk (Culex sp.), dan Rotifera sp. Hasil penelitian menunjukkan bahwa perlakuan memberikan pengaruh yang nyata (P<0,05) terhadap pertumbuhan bobot, dan kelangsungan hidup larva ikan nila (Oreochromis niloticus). Pertumbuhan tertinggi pada larva ikan nila (Oreochromis niloticus) terdapat pada perlakuan A yaitu dengan pemberian pakan alami berupa Moina sp., sedangakan pertumbuhan terendah yaitu terdapat pada perlakuan B dengan pemberian pakan berupa Rotifera sp.
Evaluation of Artificial Insemination Program for Bali Cattle in Sindue Tombusabora District, Donggala Regency
Authors: Mangun Mardiah , Malewa Amiruddin Dg. , Nur'Afni
Published: August 2022

Tujuan penelitian ini adalah untuk mengetahui tingkat keberhasilan program inseminasi buatan pada sapi Bali di Kecamatan Sindue Tombusabora Kabupaten Donggala. Penelitian dilaksanakan di Kecamatan Sindue Tombusabora Kabupaten Donggala, pada tanggal 15 April-15 Mei 2021. Materi yang digunakan dalam penelitian ini yaitu sapi Bali akseptor IB pada tahun 2019 dan 2020 sebannyak 139 ekor. Variabel yang diamati meliputi Service per Conception (S/C), Conception Rate (CR), dan Calving Rate (CvR). Penelitian ini menggunakan metode survey dengan cara sensus dan adapun data yang di peroleh dianalisis secara deskriptif. Hasil penelitian menunjukkan bahwa pada tahun 2019 dan 2020 rata-rata umur peternak berkisar antara 15 dan 64 tahun, tingkat pendidikan peternak pada tahun 2019 di dominasi oleh lulusan SD sebesar 54,76%, kemudian SMP 30,95%, dan SMA 14,28%. Pada tahun 2020 tingkat pendidikan peternak lulusan SD sebesar 57,69%, SMP 26,92%, dan SMA 15,38%. Lama beternak pada tahun 2019 dan 2020 rata-rata 6-10 tahun. Hasil pelaksanaan program IB menunjukkan bahwa nilai S/C pada tahun 2019 sebesar 1,36 dan tahun 2020 sebesar 1,40, dengan rata-rata 1,38. CR tahun 2019 sebesar 74,60% dan pada tahun 2020 sebesar 68,42%, dengan rata-rata 72,51%, sedangkan nilai CvR tahun 2019 sebesar 68,25% dan pada tahun 2020 sebesar 64,67%, dengan rata-rata 66,36%. Hasil penelitian menunjukkan bahwa pelaksanaan program IB pada sapi Bali di Kecamatan Sindue Tombusabora Kabupaten Donggala menunjukkan hasil yang sangat baik.
Sex Ratio of Endemic Ricefish Oryzias celebensis in South Sulawesi
Authors: Hasanah Nur , Andy Omar Sharifuddin Bin , Tresnati Joeharnani
Published: August 2022

Perairan tawar Sulawesi Selatan memiliki 6 spesies ikan medaka endemik dari genus Oryzias, spesies yang paling terkenal diantara ke-6 spesies tersebut ialah Oryzias celebensis. Ikan medaka endemik Oryzias celebensis dijadikan sebagai komoditi ikan hias. Habitat ikan tersebut di Sungai Pattunuangasue dan Leang-leang. Tujuan penelitian untuk mengetahui keseimbangan populasi ikan medaka endemik Oryzias celebensis. Penelitian dilakukan pada bulan Oktober 2015 hingga April 2016 di Sungai Pattunuangasue dan Sungai Leang-leang, Kabupaten Maros, Sulawesi Selatan. Rasio kelamin ditentukan berdasarkan frekuensi ikan jantan dan betina yang didapat dari semua sampel yang tertangkap selama penelitian. Hasil penelitian menunjukkan rasio kelamin ikan medaka endemik Oryzias celebensis di Sungai Pattunuangasue dan Sungai Leang-leang tidak seimbang (tidak mengikuti pola 1:1).
Effect of Basil Leaves Ekstract (Ocimum basilicum L.) on Hatching Rate of Carp (Cyprinus carpio) Eggs Infected With Fungus
Authors: Rukka Andi Heryanti , Mangitung Septina F. , Fauzan Aan
Published: August 2022

Salah satu pengendalian penyakit akibat jamur pada telur ikan mas adalah adalah dengan memanfaatkan tanaman tradisional yang bersifat anti jamur seperti penggunaan daun kemangi. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak daun kemangi (Ocimum basilicum L.) terhadap daya tetas telur ikan mas (Cyprinus carpio) yang terserang jamur. Pemberian ekstrak daun kemangi (Ocimum basilicum L.) diharapkan mampu meningkatkan daya tetas telur ikan mas (Cyprinus carpio) yang terserang oleh jamur. Desain penelitian menggunakan Rancangan Acak Lengkap (RAL). Perbedaan dari dosis ektrak daun kemangi antara lain Perlakuan A (0 mg/L), B (55 mg/L), C (60 mg/L), D (65 mg/L), dan E (70 mg/L). Perlakuan dilakukan dengan merendam telur ikan mas (Cyprinus carpio) ke dalam media perndaman selama 20 menit, kemudian telur ikan mas dimasukan kembali ke dalam wadah penetasan, selanjutnya telur diamati menggunakan mikroskop setiap 1×120 menit. Data prevalensi dan data Hatching rate dianalisis menggunakan analisis ragam ANOVA dengan bantuan minitab 16. Jika terdapat perbedaan perlakuan maka dilanjutkan dengan uji Beda Nyata Jujur (BNJ). Data kelangsungan hidup dan data kualitas air dianalisis deskriptif. Hasil penelitian menunjukan pemberian daun kemangi berpengaruh nyata terhadap daya tetas telur ikan mas. Perlakuan dengan dosis 65 mg/L daun kemangi menghasilkan daya tetas telur tertinggi.
The effect of ethical values on Islamic banking performance
Authors: As Sahara Masyitah , Setiawan Doddy
Published: August 2022

This research aims to determine the effect of ethical values on the financial performance of Islamic banking in Indonesia. This study uses the zakat disclosure index (ZDI) and the charity disclosure index (CDI) (Al-Homaidi, Al-Matari, Anagreh, Tabash, & Mareai Senan, 2021; Tuan Ibrahim, Hashim, & Mohamad Ariff, 2020) to measure ethical values and the capital adequacy ratio (CAR) to measure bank financial performance. This study hypothesizes that ethical values are positively related to bank financial performance. Data were collected from the zakat and charity disclosures made in the annual reports of 14 Islamic banks in Indonesia for ten years (2010–2019). The results showed that the ethical values, namely ZDI and CDI, positively affect the bank’s financial performance. The research limitation is the small number of samples because the number of Islamic banks in Indonesia is only 14. Future research is expected to increase the number of samples not only from Indonesia but also from other Muslim countries, as well as add further dimensions to measuring ethical values. This study provides an additional explanation of the relationship between ethical values and bank financial performance by investigating zakat and charity disclosure in Islamic banking in Indonesia, the country with the largest Muslim population globally.