bluuebunny/crossref_metadata_2025 huggingface dataset:
A pesquisa de representação social na área de ensino-aprendizagem: elementos do estado da arte
Authors: Rangel Mary
Published: September 2019

A pesquisa de pósdoutorado, Teoria de representação social: o quadro teórico da Psicologia Social e aplicações atuais à pesquisa na educação (Rangel, 1997), teve como um dos seus objetivos a análise de dissertações e teses contemporâneas (anos 90) que aplicaram a teoria, trazendo contribuições particularmente à área de ensino-aprendizagem. Este estudo, então, possibilitou - nos limites das pesquisas alcançadas - identificar elementos do estado da arte, sem perder de vista a crítica à Teoria de Representação Social (TRS), com particular consideração a Spink (1996). Ainda, tratando-se da TRS, procurou-se observar, pela sua importância na estrutura das representações, componentes do núcleo central da sua aplicação nas pesquisas. No segmento conclusivo, apresentam-se sugestões ao avanço e refinamento da construção teórica.

Palavras-Chave: representação social; pesquisa; ensinoaprendizagem; estado da arte.

Abstract

The research of pos-doctorate, Theory of the Social Representation: the theoretical table of the Social Psychology and its applications of the present time to the research in Education (Rangel, 1997), had as one of the aims the analysis of dissertations and the contemporary theses (90) that applied the theory, bringing contributions, especially in teaching-apprenticeship. In this study could be identified (in the limits of the research) the elements of the state of art  with critical to the social representations theory (SRT), considering Spink (1996). About the Social Representation Theory, some components of the core of its application in research were observed by the importance in the structure of the representations. In the final segment, suggestions are presented to the advancement and refinement of the theorical construction.

Keywords: social representations; research; teaching-learning; state of art.
Da educação do juízo de gosto
Authors: Gorovitz Matheus
Published: September 2019

Discorre sobre a necessidade do ensino das artes e da sua história na educação. Visa educar o juízo de gosto para assim instrumentar o estudante a identificar a beleza como expressão da totalidade humana. Corrobora a noção de que a formação do cidadão, do artista e do ser emancipado são interdependentes. Define os termos capazes de conferir disciplinaridade ao ensino das artes, ao reconhecer na estética o campo disciplinar que tem como objeto de estudo a práxis humana, quando esta visa objetivar, através da obra de arte, a conjugação das dimensões subjetiva e objetiva, individuais e sociais, ou seja, o ser na totalidade. Situa as categorias citadas: julgamento de gosto, totalidade, belo, autonomia, estética. Sugere um roteiro de leitura da obra de arte inferido das premissas conceituais.

Palavras-Chave: estética; belo; gosto; totalidade; autonomia; cidadania.

ABSTRACT

It discourses on the need to teach art and its history on education. It aims to educate the judgement of taste so that it enables students to identify beauty as an expression of totality. It confirms the idea that the development of citzenship, artists and emancipated human beings are interrelated. It defines the terms that enables to check disciplinarity to the teaching of art in such a way that it recognizes on aesthetics the discipline that has as a subject of study the human praxis when that aims to show, through a work of art, the conjugation of subjective and objective, individual and social dimensions, in short, the human being as a whole. It places the categories already mentioned - judgement of taste, wholeness, beauty, autonomy and aesthetics. It suggests a methodology to read a work of art deduced from the concept premises.

Keywords: aesthetics; beauty; taste; totality; autonomy; citzenship.
Interesse e desinteresse no magistério oficial paulista (1902-1910)
Authors: Pereira Gilson
Published: September 2019

A partir da análise dos textos publicados na Revista de Ensino, publicada pela Associação Beneficente do Professorado Público de São Paulo, pretende demonstrar que a alquimia simbólica de se mostrar convenientemente desinteressado e de proclamar o desinteresse adquiriu, para o campo educacional, a forma específica da ocultação do interesse em nome de valores sublimes, expressa numa recusa, ora velada, ora explícita, da dimensão econômica da vida social. Essa foi uma forma de estratégia adequada aos jogos propriamente simbólicos praticados no Estado de São Paulo, durante o processo de constituição e autonomização do campo educacional.

Palavras-chave: interesse; valores; profissão docente; campo educacional.

Abstract

Based on the analysis of some articles published in Revista de Ensino, organ from the São Paulo Public Teaching Charity Association, this study aims to demonstrate that the symbolic alchemy of showing conveniently a detachment and to proclaim disinterest obtained, for the educational area, the specific feature of the hidden interest in name of the sublime values, expressed in a refusal either veiled or clear, of the social life economic dimension. It was a strategic way suitable to the properly symbolic games practiced, in São Paulo State, during the constitution and autonomization process of the educational area.

Key-words: interest; value, academician; educational area.
Shrinking municipalities and their budgetary revenues on the example of the Warmian-Masurian Voivodeship in Poland
Authors: Wichowska Anna
Published: October 2019

Research background: Adverse demographic changes in many local administration units around the world lead to their shrinkage. These processes are usually accompanied by economic changes. The economic consequences of shrinkage can be assessed based on the budgetary revenues of local units, which are largely dependent on the local population and the demographic structure.
Purpose of the article: The aim of this article is to evaluate the shrinkage of Polish municipalities and the effects of population change on the budgetary revenues of local administration units. The analysis was conducted in selected municipalities of the Warmian-Masurian voivodeship, which is the least economically developed region in Poland. The analysis covered the period between 2012 and 2017.
Methods: The shrinkage of municipalities was evaluated with the use of the methods proposed by the Shrinking Cities International Research Network (SCIRN). According to this methodology, a local unit shrinks when the annual decrease in population exceeds 0.15% for more than five consecutive years. The influence of demographic changes on the budgetary revenues of municipalities was evaluated with the use of linear correlation analysis (Pearson's r) as well as a survey conducted among municipal treasurers in the Warmian-Masurian voivodeship. 
Findings & Value added: Symptoms of shrinkage were described in selected municipalities of the Warmian-Masurian voivodeship. The presence of correlations between different categories of budgetary revenues and demographic changes was confirmed. The results of the study and the formulated practical recommendations constitute constructive inputs to the discussion on possible solutions to the analyzed problem. They can also be used in further research to analyze other aspects of municipal budgets (the consequences of depopulation for budgetary expenditures, municipal debt, etc.) or conduct comparisons with other regions in Poland and in the world.
Becoming business-like: the determinants of NGOs? marketization turning into social enterprises in Poland
Authors: Mikołajczak Paweł
Published: October 2019

Research background: NGOs face an increasing expectation to be more business-like. They are becoming involved in selling services by performing a commercial activity, which, in turn, is a basic condition for creating social enterprises. The changes related to this approach are an essential condition for their survival and a significant reason for developing their new form as social enterprises. On the other hand, there is no lack of critical opinions related primarily to mission volatility. Currently, a discussion is taking place in the literature on factors that may affect NGOs? marketization; these, however, have not been empirically verified yet. The identified research gap constituted a major challenge for the author.
Purpose of the article: The purpose of this paper is to verify whether conducting a business activity influences the entrepreneurial way of NGOs? operation, and to indicate the factors that have a significant impact on their marketization.
Methods: On the basis of a representative national survey of 3,800 NGOs, including 412 social enterprises in Poland. a one-factor analysis of variance (ANOVA) and a stepwise backward regression analysis were carried out.
Findings & Value added: The analysis of the results confirms that there are significant differences between NGOs operating as social enterprises and NGOs not performing a business activity. In contrast with the existing literature, this study indicates that social enterprises have less diversified revenue sources and use a more or less democratic governance model. Moreover, Polish social enterprises less frequently adjust their policy direction to donors? interests. The factors significantly affecting NGOs? marketization include action strategies for several years, activity in favor of external benefit takers, close business cooperation, lack of permanent financing sources, and regular activity combined with flexible working time.
Modernización y naturaleza. Auge y declive de la hacienda cañera y de fincas cafetaleras en el distrito de Teotitlán del Camino, Oaxaca, 1888-1917
Authors: Almazan Marco Aurelio
Published: September 2019

Los análisis de la aplicación de las políticas liberales decimonónicas sobre tierras y aguas en México han considerado primordialmente variables sociopolíticas y económicas para explicar sus repercusiones en los ámbitos regionales. El propósito del presente artículo es sumar la observación de la influencia de la naturaleza en los resultados de esas políticas, particularmente en el distrito de Teotitlán del Camino, Oaxaca. Mediante la identificación de lo acaecido en sus dos espacios socionaturales, conformados por características distintivas, se ilustrará que la naturaleza posibilitó el impulso de proyectos cañeros y cafetaleros privados, pero también constituyó un actor principal en su posterior declive.
THE PERFORMANCE OF RELIGIOUS TEACHERS AT ISLAMIC HIGH SCHOOL IN NUNUKAN ISLAND, NORTH KALIMANTAN
Authors: Hasnah Hasnah
Published: September 2019

This study aims at determining the performance of religious education teachers in Aliyah Madrasas on Nunukan Island, North Kalimantan, and increasing the role of performance of religious education teachers in carrying out their duties to Aliyah Madrasas on Nunukan Island, North Kalimantan. This type of research is qualitative research located on Nunukan Island, North Kalimantan. Methods of data collection are carried out using observation, interview and documentation techniques. Data analysis carried out was data reduction, data presentation and data verification. Then the data validity is tested by observation and triangulation.The results showed that performance of religious education teachers in the Aliyah Madrasah on Nunukan Island in North Kalimantan is relatively good. However, it still needs to be improved, especially in terms of discipline, ability in the preparation of components of learning devices, as well as the ability to use learning media. 2) Teacher education strategies to improve their performance by conducting continuous evaluations, supervising and evaluating administration, 3) Supporting factors for the performance of religious education teachers, namely a conducive learning atmosphere, harmonious relationships, the ability of the headmaster to motivate teachers. While the inhibiting factors are the lack of facilities and infrastructure needed by religious education teachers, small and minimal income.
TINGKAT LITERASI MEDIA BERBASIS KOMPETENSI INDIVIDU DI KALANGAN SISWA SMA NEGERI 17 MAKASSAR
Authors: Latief Rahmawati
Published: September 2019

Nowadays the mass media is experiencing very rapid development. Various positive and negative impacts certainly cannot be ignored. This impact hits parents, adults, teenagers and children. Adolescents are a group that is vulnerable to the negative effects of mass media by which media literacy movements emerge as solutive actions over concerns about negative media influences. The ability of media literacy is very necessary so that the media can be used intelligently and wisely. The purpose of this study are: (1) To determine the level of technical skills (technical expertise) of SMA Negeri 17 Makassar students in accessing computer and internet media; (2) To describe the level of critical understanding (critical understanding) of SMA Negeri 17 Makassar students in analyzing and evaluating computer and internet media content; (3) To understand the level of communicative abilities (communication skills) of SMA Negeri 17 Makassar students in establishing social relations through internet media and creating creative internet media content; (4) To find out the level of media literacy of SMA 17 Makassar students. The results of this study indicate that cumulatively the level of technical skill ability is at 99.5%, the level of critical understanding capability is at 74.7%, the level of communicative abilities is at a value of 110.3%. By referring to the values above, the level of media literacy of Makassar 17 Public High School students is 94.83% or at the Medium level.
ANALISIS FAKTOR PEMILIHAN MEDIA SOSIAL LINE DI KALANGAN REMAJA KOTA BANDUNG
Authors: Rani Nofia Nandha , Fithrah Ali Dini Salmiyah
Published: September 2019

The increasing of internet usage triggered the growth of social media activity. One of the social media which rose significantly is Line. Three years after Line debut, statistic showed that Line has 470 million users and the application has been downloaded over 1 million times in all over the world.This research is to determine what factors that influence people in Bandung City in deciding to choose social media Line. The theory that used in this research isStimulus Organism Respons Theory.. This research is using a descriptive method to visualize systematically, factually and accuracy regarding facts, characters and relation with the phenomena to be explored. Done by a survey to 180 people of Bandung City which have been chosen through multi-usage cluster sampling technique. Data that has been gathered then handle with using analysis factor method on SPSS 20.This research resulted in three factors which became the factor in choosing social media Line in Bandung area that has been obtained through analysis factor process. Those three factors in sequence are Networking Interactions factor consist of interaction and networking, User Information factor, including information, Social Simulation, User content  and Archive factor. The rest another factor that owned by the user in choosing social media Line in Bandung area.
Limfadenopatia u dzieci i dorosłych: zasady postępowania diagnostycznego
Authors: Styczyński Jan
Published: September 2019

Streszczenie

Powiększenie węzłów chłonnych (limfadenopatia) jest jednym z najczęstszych objawów klinicznych, zwłaszcza u dzieci. U ok. 50% zdrowych dzieci dochodzi do powiększenia węzłów chłonnych; najczęściej w wieku 2-10 lat. Celem pracy jest przedstawienie zasad postępowania diagnostycznego u pacjenta z limfadenopatią, jak również omówienie jej przyczyn, zasad rozpoznawania oraz przedstawienie rekomendacji postępowania klinicznego u pacjenta z powiększeniem węzłów chłonnych. Etiologię limfadenopatii u dzieci i dorosłych oraz związane z tym ukierunkowanie diagnostyki różnicowej można określić wg kilku reguł przedstawionych akronimami w języku angielskim: MIAMI, CHICAGO, wg liter alfabetu lub lokalizacji. W postępowaniu diagnostycznym obowiązuje czteroetapowy proces: (1) badanie podmiotowe (wywiad) i przedmiotowe; na tym etapie najczęściej zapada decyzja o hospitalizacji; (2) badania laboratoryjne; (3) badania obrazowe: USG i/lub tomografia komputerowa; (4) otwarta biopsja węzła. W chwili obecnej otwarta biopsja węzła i badanie histopatologiczne są złotym standardem diagnostycznym limfadenopatii u dzieci. Ze względu na ryzyko maskowania lub opóźnienia rozpoznania chłoniaka lub białaczki do czasu ustalenia jednoznacznej diagnozy nie należy podawać steroidów. U dzieci z ostrym jednostronnym powiększeniem przednich węzłów chłonnych szyjnych oraz z objawami ogólnymi powinna zostać zastosowana antybiotykoterapia empiryczna.
Znaczenie techniki aCGH w nowotworach mieloproliferacyjnych – przegląd literatury
Authors: Osmańska Katarzyna , Pilarska-Deltow Maria , Haus Olga
Published: September 2019

Streszczenie

Nowotwory mieloproliferacyjne (MPN) są klonalnymi chorobami komórek macierzystych szpiku, które charakteryzują się proliferacją jednej lub więcej linii mieloidalnych krwiotworzenia: granulocytowej, czerwonokrwinkowej i/lub megakariocytowej. Do MPN BCR-ABL1(-) zalicza się m.in. czerwienicę prawdziwą (PV), nadpłytkowość samoistną (ET) oraz pierwotną mielofibrozę (PMF). Nowotwory mieloproliferacyjne BCR-ABL1(-) należą do najmniej poznanych nowotworów układu krwiotwórczego pod względem nabytych zmian genetycznych. Badania nad MPN trwają od ponad 60 lat. Podobieństwo objawów klinicznych wskazuje na wspólną patogenezę PV, ET i PMF. Głównym celem prowadzonych badań jest wytypowanie markerów, które nie tylko pomogą w diagnostyce poszczególnych typów MPN czy w klasyfikacji chorych do grup ryzyka, ale mogłyby być także celem terapeutycznym. Głównym celem terapii jest przedłużenie życia pacjentów, w tym także zminimalizowanie prawdopodobieństwa transformacji w ostrą białaczkę. aCGH jest niewątpliwie techniką bardzo przydatną klinicznie, która, choć nie znalazła jeszcze rutynowego zastosowania w klinice hematoonkologii, to wykorzystywana jest w coraz większej liczbie badań, zwłaszcza do analizy nowotworów, w których istotne są aberracje niezrównoważone. Niniejsza praca przedstawia zastosowanie techniki aCGH w nowotworach mieloproliferacyjnych.
Strategie doboru krwinek czerwonych dla biorców w różnych sytuacjach klinicznych
Authors: Fabijańska-Mitek Jadwiga
Published: September 2019

Streszczenie

Przed transfuzją krwinek czerwonych wykonuje się rutynowe testy immunohematologiczne, dzięki którym przetacza się biorcom serologicznie zgodną krew dawców. Wyzwaniem dla serologów jest dobór koncentratu krwinek czerwonych (KKCz), gdy uodpornieni biorcy mają alloprzeciwciała z powodu wcześniejszych transfuzji lub ciąż albo wytworzą autoprzeciwciała w niedokrwistościach autoimmunohemolitycznych (NAIH). Wyzwaniem dla klinicystów jest pilna, ratująca życie transfuzja bez próby zgodności. Są to przetoczenia nagłe (krwawienie) oraz sytuacje, gdy brak jest krwi o wyjątkowych fenotypach. Ważne jest tworzenie narodowych rejestrów rzadkich dawców krwinek czerwonych i uczestnictwo w rejestrze międzynarodowym oraz przekazywanie informacji o skutkach niezgodnego przetoczenia i leczeniu ograniczającym hemolizę. Inne problemy dotyczą szczególnych grup biorców krwi, czyli: płodów, noworodków, niemowląt i pozostałych dzieci. Różnią się one cechami hematologicznymi i immunologicznymi, więc testy zgodności muszą się też różnić. Skomplikowane są transfuzje po transplantacjach komórek krwiotwórczych i narządów, gdy z powodu immunologicznego chimeryzmu dochodzi do hemolizy. Ścisła współpraca między klinicystami i immunohematologami jest konieczna, by zapewnić bezpieczeństwo transfuzji w wymienionych sytuacjach klinicznych opisanych w prezentowanej publikacji.
ABC of viral infections in hematology: focus on herpesviruses
Authors: Styczyński Jan
Published: September 2019

Viruses are a form of life that possess genes but do not have a cellular structure. Viruses do not have their own metabolism, and they require a host cell to make new products; therefore, they cannot naturally reproduce outside a host cell. The objective of this paper is to present the basic practical clinical roles of viruses in patients with hematological diseases including malignancies and non-malignan- cies, as well as those undergoing hematopoietic cell transplantation (HCT), with the focus on herpesviruses causing latent infections in severely immunocompromised patients. From the hematologist point of view, viruses can play a major role in four conditions: causing infections; causing lymphoproliferations and/or malignancies; causing (pan)cytopenia; and used as vectors in treatment (e.g., gene therapy, CAR-T cells). Taking into account the role of viruses in hematology, infection is the most frequent condition. Among DNA viruses, the highest morbidity potential for human is expressed by Herpesviridiae (herpesviruses), Adenoviridae (adenovirus; ADV), Polyomavirus (BKV, JCV), and Bocavirus. RNA viruses can play a role in pathogenesis of different clinical conditions and diseases: lymphoproliferative disorders and malignancy, possibly causing NHL, AML, MDS, and others (HCV, HIV, and others); pancytopenia and aplastic anemia (HIV, HCV, Dengue virus); respiratory infections (community-acquired respiratory virus infections; CARV) caused by Orthomyxoviruses (e.g. influenza A/B), Paramyxoviruses (e.g. human parainfluenza virus PIV-1, -2, -3, and -4; respiratory syncytial virus RSV-A and -B), picornaviruses (e.g., human rhinovirus), coronaviruses (e.g., human coronavirus), Pneumoviridiae (e.g., human metapneumovirus), and potentially other viruses.
Efficient Astronomical Data Condensation Using Approximate Nearest Neighbors
Authors: Łukasik Szymon , Lalik Konrad , Sarna Piotr , Kowalski Piotr A. , Charytanowicz Małgorzata , Kulczycki Piotr
Published: October 2019

Extracting useful information from astronomical observations represents one of the most challenging tasks of data exploration. This is largely due to the volume of the data acquired using advanced observational tools. While other challenges typical for the class of big data problems (like data variety) are also present, the size of datasets represents the most significant obstacle in visualization and subsequent analysis. This paper studies an efficient data condensation algorithm aimed at providing its compact representation. It is based on fast nearest neighbor calculation using tree structures and parallel processing. In addition to that, the possibility of using approximate identification of neighbors, to even further improve the algorithm time performance, is also evaluated. The properties of the proposed approach, both in terms of performance and condensation quality, are experimentally assessed on astronomical datasets related to the GAIA mission. It is concluded that the introduced technique might serve as a scalable method of alleviating the problem of the dataset size.
Ovarian Activity and the Size of Oocytes in Ovarian Follicles in Sexually Mature Gilts in Individual Seasons
Authors: Kyzeková P. , Belková L. , Macák V. , Reichel P. , Link R. , Novotný J. , Bárdová K.
Published: October 2019

The aim of this study was to evaluate ovarian activity and the size of oocytes in ovarian follicles in sexually mature Landrace-Yorkshire gilts in relation to the individual seasons of the year. The study was carried out on 240 gilts slaughtered at an abattoir during the four yearly seasons. The size and weight of the ovaries, the number of follicles and corpora lutea (CL) according to individual size categories were evaluated. The oocytes were aspirated from follicles and their sizes were measured. Our evaluation of the size of the ovaries showed that they were the largest in autumn, when their mean length reached 25.8 ± 3.4 mm, while in winter their mean length was 24.2 ± 2.9 mm. The smallest weight of the ovaries was determined in autumn (mean 5.7 ± 1.4 g) and the highest in spring (mean 6.2 ± 2.2 g). The largest number of follicles in the ovaries of the gilts was recorded during the autumn months, with a predominance of follicles up to 3 mm (mean number 17.9 ± 7.5). The largest number of corpora lutea was observed in spring (mean number 12.1 ± 2.6) and the smallest in winter (mean number 6.1 ± 1.1). The oocytes from follicles of up to 3 mm size, were the smallest in spring (mean size 16.99 × 103 ± 3.42 × 103 µm2) and the largest in winter (mean size 18.90 × 103 ± 2.99 × 103 µm2). In total, the largest oocytes were aspirated from 4—6 mm follicles in autumn (mean size 19.60 × 103 ± 5.37 × 103 ± µm2). The values recorded indicated that the seasons affected the ovarian activity and the growth of oocytes in gilts.
The Design of a Homogeneous Magnetic Field Generator for Applications in Membrane Making
Authors: Gayatri Ida Ayu Putu Inten , Rupiasih Ni Nyoman , Sumadiyasa Made
Published: September 2019

It has been designed a homogeneous magnetic field (B) generation system in a particular room. This is important to conduct research related to the effects of magnetic field exposure on chemical reactions, especially in the process of making membranes. The development was carried out using four Helmholtz coils which radius (R) of 15 cm and number of turn (N) of 130 turns, that connected in parallel and coaxial. The both coils were fixed at the same distance as the radius of the coil that intended to get a homogeneous magnetic field between the both coils. The design has been tested by measuring a magnetic field generated as function of a current (I) given. The results show that, for x is the distance from the midpoint of the both coils to a certain distance, the homogeneous magnetic field obtained in the region of -7 cm < x <+7 cm, the area between the both coils. The magnitude of the homogeneous magnetic field produced depends on the electric current given.
The Gambaran Histologi dan Histomorfometri Limpa Kambing Peranakan Etawah
Authors: Yanti Tri Ulfah Arema , Suwiti Ni Ketut , Setiasih Ni Luh Eka
Published: September 2019

Telah dilakukan penelitian tentang gambaran histologi dan histomorfometri limpa kambing peranakan etawah (PE). Sampel penelitian ini diambil dari limpa 10 ekor kambing PE jantan dan betina yang dipotong di tempat pemotongan hewan Kampung Jawa, Denpasar, Bali, selanjutnya difiksasi dalam larutan Neutral Buffer Formalin 10% kemudian diproses untuk pembuatan preparat histologi berdasarkan metode Kiernan dengan teknik pewarnaan Hematoksilin-Eosin (HE). Limpa kambing PE tersusun atas kapsula, pulpa putih dan pulpa merah. Histomorfometri limpa kambing PE jantan dan betina diperoleh hasil masing-masing memiliki ketebalan kapsula 128,58±0,37 µm dan 163,40±0,35 µm, ketebalan trabekula 125,68±0,13 µm dan 131,45±0,28 µm, dan diameter pulpa putih 466,63±0,15 µm dan 392,40±0,30 µm. Disimpulkan bahwa jenis kelamin mempengaruhi struktur histologi dan histomorfometri limpa kambing peranakan eatawah (PE)
Reaksi Pasar Modal Terhadap Pengumuman Right Issue pada Perusahaan yang Terdaftar di Bursa Efek Indonesia
Authors: Amir Pita Qurnia , Suaryana I. G. N. Agung
Published: September 2019

This research aims to determine whether there is a market reaction to the announcement of the rights issue. This research was conducted on the Indonesia Stock Exchange (IDX) in publicly listed companies that conducted rights issues during the period 2011-2017 with a population of 143 companies. The sample selection uses non-participant observation method with purposive sampling technique, obtained a sample of 103 companies. The analysis technique used is to test one sample t-test on the cumulative abnormal return. Based on the results of the analysis conducted, it was found that there is no market reaction to the announcement of the rights issue, which means the announcement of the rights issue does not have information content so it does not affect the investor's preference in making decisions.

Keywords: Right issue, abnormal return, market reaction.
PENGARUH KUALITAS JASA TERHADAP KEPERCAYAAN DAN KEPUASAN PADA TOURIST INFORMATION CENTRE SURABAYA
Authors: Maharani Putri Kurnia , Suardana I Wayan , Eka Mahadewi Ni Putu
Published: September 2019

Tourist Information Centre is one of the important tourism supporting facilities in a tourist destination precisely in the city of Surabaya. The purpose of this study to determine the effect of service quality from the Tourist Information Center to the trust and satisfaction of tourists who visit. This research was conducted at the Tourist Information Center of Surabaya City. Types of data used are qualitative and quantitative data, data collection using questionnaire method, interview and observation. Determination of sample is done by purposive sampling whereas sampling method using representative method of number of indicator multiplied 5 until 10 with get result of 180 tourist. The collected data were analyzed by path analysis method using PLS.The result of the research shows that service quality has significant effect to trust havin gprobability value <0,05, service quality have significant influence to satisfaction with probability value <0,05 and trust have significant effect to satisfaction with probability value <0,05. It states that all hypotheses are accepted. The trust variable proves to be an intervening of 0.6873 which means that variable increasing trust will be a good bridge to the relationship between service quality and satisfaction. The suggestion to increase Tourist Information Center in order to facilitate the access of tourists in obtaining in formation about tourism. And more to place the location to be easily known by tourists.
Characteristic of Patients with Gastric Perforation due to Peptic Ulcer in Dr. Soetomo General Hospital Surabaya in the Period of January - December 2016
Authors: Agustin Esthiningrum Dewi , Putro Mamiek Dwi , Purbayu Herry
Published: September 2019

Aim: This study aims to study the profile of patients with gastric perforation caused by peptic ulcer. Method: This is a retrospective study by obtaining patients data from medical records in the Medical Record Centre of Dr. Soetomo General Hospital during the period of January - December 2016 and analyzed descriptively. Result: 66 patients were identified (45 male and 21 female), most of them were between age 60 - 69 years old, and live in Surabaya (45.45%). 30.3% of patients No malignancy was found during the anatomic-pathological examination. 30.3% of patients have a long term NSAID taking, while 53.03% of patients came with a habit of traditional medicine consumption. Perforations were mostly located 1 - 5 cm pre-pyloric and between the range 0.5 - 1 cm in diameter (56.6% and 69.7%, respectively). Conclusion: With the lack of information, it still needs further studies with more completed data for better accuracy.
EFEK ANTIOKSIDAN FRAKSI ETIL ASETAT MINUMAN SINOM CAMPURAN JERUK NIPIS DAN MADU (curcuma domestica val-tamarindus indica L.) TERHADAP GULA DARAH TIKUS PUTIH SPRAQUE DAWLEY DIABETES MELITUS
Authors: Wiradnyani N. K. , Arimathea I M. M.
Published: September 2019

Sinom drinks mixed with lime and honey are made from rhizome of turmeric and young tamarind leaves which are added with lime juice and honey. The aim of the study was to determine the effect of antioxidant compounds of ethyl acetate on sinom drinks mixed with lime juice and honey (SCJM) various doses on fasting blood sugar spraque dawley (SD) white rats diabetes mellitus. Experimental research using RAK, ANOVA analysis with further BNT testing consisted of two stages: 1) test the antioxidant capacity of various solvents of SCJM yielding 29691.1 µg AAEAC / g ingredients namely the highest number of ethyl acetate fractions of n- hexane, chloroform, and water. Phase 2 Ethyl acetate fraction of SCJM was further tested in vivo to SD white rats with diabetes mellitus with various doses, namely: control (-) normal mice, 50, 100, 150, 200 mg/dl BW, control (+) of diabetic rats. The results of the study of the effect of the antioxidant compound SCJM  ethyl acetate fraction of various doses significantly affected (p <0.01) in decreasing fasting blood sugar (GDP) white SD diabetes mellitus rats, a dose that can reduce the lowest GDP based on statistical tests is 150 mg/kg BW of rats, 168.4 mg/dl from other doses.

Keywords: ethylacetate, blood sugar, antioxidant, sinom
ISOLASI DAN IDENTIFIKASI GOLONGAN FLAVONOID PADA EKSTRAK ETIL ASETAT DAUN GEDI (Abelmoschus manihot L.)
Authors: Theodora C. T. , Gunawan I W. G. , Swantara I M. D.
Published: September 2019

The purpose of this experiment was to determine the flavonoid compounds in ethyl acetat extract of gedi leaves (Abelmoschus manihot L.). In this study, the method of extraction was maceration with semipolar solvent (ethyl acetat), flavonoid phytochemical screening, separation and purity test with chromatography and then identification of the compound using FTIR and UV-Vis spectrophotometer with shear reagent method. Analysis of FTIR spectra showed some functional groups such as OH, CH aliphatic, C = O, CO alcohol, C = C aromatic, and CO ether, whereas the analysis with UV-Vis spectra indicated the presence of band I at a wavelength of 409.4 nm and 238.40 nm for band II which is the auron specific wavelength. After the addition of shift reaget, there was a substitutions of OH groups in C-4, C-6 and C-3' and OR at C-4'. The flavonoid compounds contained in ethyl acetate extract of gedi leaf is suggested to be auron, 3',4,6-trihydroxy,4-alkoxy-auron.

Keywords: auron, ethyl acetat extract, flavonoids, gedi leaf, isolation
AKTIVITAS ANTI-RHEUMATOID ARTHRITIS DARI BRAZILIN DAN BRAZILEIN SECARA IN SILICO
Authors: Amarawati G. A. K. , Susanti N. M. P. , Laksmiani N. P. L.
Published: September 2019

Rheumatoid arthritis is an autoimmune disease that occur by inflammation chronic which persist as a permanent symptom. That inflammatory process caused joint destruction. Production of pro-inflammatory sytokin such as Tumor Necrosis Factor Alpha (TNF-?) stimulate an autoimmunity. Active TNF-? plays a role in the occurrence of chronic inflammation, in which the formation of active TNF-? is regulated by TNF-? Converting Enzyme (TACE). Brazilin and brazilein are known to have anti-inflammatory activity and immunommodulator potentially as anti-rheumatoid arthritis. The purpose of this study were to determine the affinity and mechanisms of brazilin and brazilein against TACE proteins as anti-rheumatoid arthritis perfomed using molecular docking method. The study was conducted exploratively with several steps such as databases preparation of 3D structures brazilin, brazilein, TACE protein, optimization of brazilin and brazilein 3D structures, protein preparation, molecular docking method validation, and docking brazilin and brazilein in these proteins. The docking results are assessed from the binding energy and hydrogen bonds formed between brazilin and brazilein in proteins. The smaller value to the binding energy, will made the bond between brazilin and brazilein with proteins will be stronger and more stable. The results showed that brazilin and brazilein have activities as anti-rheumatoid arthritis because they are able to inhibit TACE proteins with respective bond energy values -7,24 for brazilin and – 7,59 kcal/mol for brazilein. These results show that brazilin and brazilein have the potential to inhibit inflammatory process and joint destruction in rheumatoid arthritis.

Keywords : brazilin, brazilein, in silico, rheumatoid arthritis
MOLECULAR DOCKING AKTIVITAS ANTIKANKER DARI KUERSETIN TERHADAP KANKER PAYUDARA SECARA IN SILICO
Authors: Rastini M. B. O. , Giantari N. K. M. , Adnyani K. D. , Laksmiani N. P. L.
Published: September 2019

Breast cancer can be initiated by either overexpression of HER-2 protein which can induce dimerization and autophosphorylation so that it triggers the activation of Focal Adhesion Kinase (FAK) resulting in migration and metastasis in breast cancer cells. Quercetin which has another name 3,5,7,3 ', 4'-pentahydroxyflavon with the molecular formula of (C15H10O7) is a flavonoid compound which is very widely found in nature. The purpose of this study was to determine the mechanism of inhibition of overexpression of HER-2 proteins by quercetin compounds by in silico molecular docking. In silico molecular docking was carried out in several stages namely method validation, optimization of 3D quercetin compound structure, docking between quercetin compounds optimized with HER-2 protein based on bond energy parameters the lower the bond energy the stronger and the more stable the bond is. The results of docking expressed by the binding energy of quercetin compounds with HER-2 protein are -8.24 kcal / mol, while the energy of the native ligand bond with HER-2 protein is -10.45 kcal / mol. The bonding energy shows that quercetin compounds have the potential as breast anticancer because they can modulate the overexpression of HER-2 proteins.

 

Keywords: quercetin, breast cancer, HER-2, in silico
SUPLEMEN EKSTRAK DAUN SIRIH, Piper betle, Lin DALAM MENURUNKAN KADAR MALONDIALDEHID PADA TIKUS WISTAR
Authors: Suirta I W. , Asih I. A. R. A.
Published: September 2019

Betel leaf extract supplements, Piper betle Lin , was made by extracting maceration of betel leaves with ethanol 96%. Phytochemical screening of betle leaf extract obtained secondary metabolites such as : terpenoids, steroids, phenolics, and saponins . The results of the antioxidant activity test test showed that n-hexane fraction was more reactive as an antioxidant (IC50 26,73 mg/L)  than the diethyl ether fraction (IC50 114,54 mg/L). The MDA analysis showed that the betel leaves have a very good ability to reduce MDA levels. The concentration of MDA with addition of allopurinol (as positive control) was 0,41±0,0021?L/mL, while with addition of betel leaves the level was 0,44±0,0021?L/mL. The structure identification obtained active antioxidant compounds such as: cavicol, eugenol, caryophilene and isoeugenol.

Keywords : betel leaf, malondialdehyde, Piper betle, wistar rat
UJI AKTIVITAS ANALGESIK EKSTRAK ETANOL DAUN JERUK LIMAU (Citrus amblycarpa (Haskk.) Ocshe) PADA MENCIT JANTAN GALUR BALB/C DENGAN METODE HOT PLATE
Authors: Cahyaningsih Ni Komang , Satriawati Dewa Ayu , Wicaksana I Gde Pande Aninditha Putra , Yulita Santri , Sukarmini Ni Nyoman Fabby , Astuti Ni Ketut Widyani , Putra Anak Agung Gede Rai Yadnya
Published: September 2019

NSAID menjadi salah satu pilihan terapi untuk menghilangkan rasa nyeri.Namun, penggunaanya dalam jangka panjang dapat memicu efek samping yaitu pendarahan gastrointestinal. Oleh karena itu, diperlukan analgesik alternatif yang memiliki efek terapi yag sama dan efek samping yang lebih rendah. Salah satu tanaman yang memiliki potensi sebagai analgesik alternatif adalah Jeruk Limau (Citrus amblycarpa) yang dimanfaatkan sebagai obat kesemutan dan kram secara empiris. Penelitian ini dilakukan dengan tujuan untuk mengetahui aktivitas analgesik pada ekstrak etanol daun Citrus amblycarpa sebagai analgesik pada mencit putih jantan galur balb/c. Salah satu metode yang digunakan dalam pengujian aktivitas analgesik adalah metode Hot Plate. Penelitian dilakukan dengan membagi 30 ekor mencit ke dalam 6 kelompok kemudian masing-masing kelompok diberikan suspensi uji yang terdiri dari CMC-Na 1% sebagai kontrol negatif, suspensi natrium diklofenak dosis 6,5 mg/kgBB sebagai kontrol positif, dan suspensi ekstrak etanol daun C. amblycarpa dengan variasi dosis 100mg/kgBB, 300 mg/kgBB, dan 500 mg/kgBB. Hewan uji ditempatkan diatas Hot Plate dengan suhu 70°C pada 30 menit setelah pemberian suspensi uji dan diamati waktu respon mencit terhadap panas setiap 30 menit selama 3 jam. Hasil uji kadar air serbuk simplisia daun C. amblycarpa adalah 4,492 ± 0,0436% (b/b), persentase rendemen ekstrak metode maserasi adalah 21,403% (b/b). Berdasarkan hasil uji aktivitas analgesik ekstrak etanol daun C. amblycarpa dapat disimpulkan bahwa pemberian ekstrak dosis 100 mg/kgBB, 300 mg/kgBB dan 500 mg/kgBB memberikan aktivitas analgesik terhadap mencit dibandingkan dengan kontrol negatif (CMC-Na 1%) dengan nilai ED50 sebesar 306,667 mg/kgBB.
Authors: Sukarmini Nyoman Fabby
Published: September 2019

Retinopati diabetik (RD) merupakan komplikasi mikrovaskular DM karena adanya kerusakan pembuluh darah retina yang dapat menyebabkan kebutaan permanen. Kontrol glukosa darah yang baik terbukti mengurangi onset dan risiko perkembangan RD. penelitian ini bertujuan untuk mengetahui penggunaan obat antidiabetes pada pasien DM tipe 2 komplikasi RD dan luaran terapi dilihat dari perubahan kadar glukosa darah dan derajat RD pasien. Desain penelitian ini adalah observasional dengan pendekatan retrospektif. Data penelitian diperoleh dari rekam medis pasien DM tipe 2 komplikasi RD periode Januari 2018-Desember 2018 di RSUP Sanglah. Data derajat RD dianalisis secara deskriptif sedangkan perubahan kadar glukosa darah dianalisis secara statisik (paired t-test dan wilcoxon). Pada penelitian ini didapatkan sebanyak 29 pasien yang memenuhi kriteria inklusi dengan penggunaan obat terdiri dari insulin sebanyak 14 pasien (48,3%), OAD (oral antidiabtes drugs) sebanyak 9 pasien (31,0%) dan kombinasi OAD + insulin 6 pasien (20,7%). Rata-rata KGDP pasien menurun signifikan (p<0,05) pada penggunaan OAD, insulin, dan kombinasi OAD + insulin masing-masing sebesar 52,22±20,34; 58,86±19,29 dan 92,83±26,99 mg/dL. Rata-rata KGD2PP pasien menurun signifikan (p<0,05) pada penggunaan OAD dan insulin masing-masing sebesar 69,00±23,22 dan 79,35±31,58 mg/dL, namun pada penggunaan kombinasi OAD + insulin penurunan yang terjadi tidak signifikan (p>0,05) sebesar 67,33±49,55 mg/dL. Rata-rata HbA1c pasien menurun signifikan (p<0,05) pada penggunaan OAD, insulin dan kombinasi OAD + insulin masing-masing sebesar 1,77±0,39; 1,58±0,52 dan 1,60±0,55 %. Peningkatan derajat RD terjadi pada 5 dari 29 (17,24%) pasien.

Kata kunci: Dabetes mellitus tipe 2, Retinopati diabetik, Glukosa darah, OAD, Insulin.
Evaluasi Kualitas Pengungkapan Value at Risk Perbankan Indonesia
Authors: Wibowo Buddi , Fadhila Hasna
Published: September 2019

Market risk measurement of bank investment portfolios is a still problem not only among practitioners, but  also among academicians. The accuracy and quality of market risk disclosures are important issues because  transparency of the bank risk level encourages market control in the form of market discipline and it also  improve the quality of risk management carried out internally by the bank. This research measures the quality of Value at Risk disclosures carried out by Indonesian banks. The accuracy of Value at Risk in this research is measured from the Value at Risk component which contains information of yield volatility of bank trading treasury activities. To measure Value at Risk disclosure, this research runs various methods of Value at Risk measurement. This research shows Historical Simulation is a Value at Risk method that is most widely used by Indonesia banks. The empirical test results show that the Value at Risk parametric method using asymmetric volatility have better quality than the Value at Risk Historical Simulation method. This research shows that Value at Risk as measured by Historical Simulation method contains the least information of bank trading treasury yields.

Keywords: value at risk; disclosure; market risk; volatility
DISTRIBUSI SPASIAL GASTROPODA Littoraria scabra DI HUTAN MANGROVE PULAU TUNDA SERANG BANTEN, INDONESIA
Authors: Rial Syahrial , Karsim Nanang
Published: September 2019

Abstrak

 

Ekosistem pesisir memiliki keanekaragaman hayati yang tinggi, salah satunya adalah ekosistem mangrove. Kajian Distribusi Spasial Gastropoda Littoraria scabra di Hutan Mangrove Pulau Tunda Serang Banten, Indonesia telah dilakukan pada bulan Januari 2014. Hal ini bertujuan untuk memberikan informasi terhadap penyebaran biodiversitas Indonesia khususnya L. scabra. Pengumpulan data gastropoda L. scabra dilakukan dengan membuat transek garis dan plot yang ditarik dari titik acuan (tegakan mangrove terluar) dan tegak lurus garis pantai sampai ke daratan. Transek garis tersebut dibuat petak-petak contoh (plot) dengan ukuran 10 X 10 m2 dan di dalam ukuran 10 x 10 m2 tersebut dibuat plot kecil (sub plot) yang berukuran 1 x 1 m2 sebanyak 5 plot. Hasil penelitian menunjukkan bahwa gastropoda L. scabra terdistribusi merata di hutan mangrove Pulau Tunda Serang Banten. Kemudian komposisi dan kepadatannya lebih tinggi di bagian Timur (284 ind dan 6.31 ind/m2) daripada bagian Selatan (101 ind dan 2.24 ind/m2). Selain itu, hasil penelitian juga memperlihatkan bahwa pola distribusi gastropoda L. scabra di hutan mangrove Pulau Tunda Serang Banten (Timur dan Selatan) tergolong seragam ((I? <1).

 

Kata kunci: distribusi, gastropoda, Littoraria scabra, mangrove, Pulau Tunda, Indonesia
Pemodelan Distribusi Nitrat di Kawasan Perairan Teluk Benoa
Authors: Raharja I Made Dharma , Hendrawan I Gede , Suteja Yulianto
Published: September 2019

Teluk Benoa merupakan perairan yang dipengaruhi oleh kondisi lingkungan perairan. Nitrat adalah salah satu parameter perairan yang sangat penting bagi kelangsungan hidup biota di laut. Dari penelitian sebelumnya terkait beban pencemaran nitrat di Teluk Benoa, kondisi nitrat telah melampui kondisi baku mutu yang ditetapkan melalui Peraturan Gubernur Bali Nomor 16 Tahun 2016 tentang Baku Mutu Lingkungan Hidup dan Kriteria Baku Kerusakan Lingkungan Hidup yaitu 0,008 mg/L. Penelitian yang telah dilakukan sebelumnya masih terbatas pada analisis nitrat pada bagian permukaan perairan sehingga dari  hal  tersebut penting  halnya melakukan kajian lebih lanjut terkait  kondisi nitrat di kolom perairan Teluk Benoa. Kajian konsentrasi nitrat pada kolom perairan dapat dilakukan dengan observasi secara langsung dilapangan, namun membutuhkan waktu yang cukup lama dan biaya yang tinggi. Sehingga pada penelitian ini digunakan pemodelan numerik. Pemodel numerik yang digunakan dalam penelitian ini adalah Finite Volume Coastal Ocean Model (FVCOM) yang dimodelkan secara 3-D. Dalam analisis distribusi nitrat pada studi ini digunakan persamaan momentum dan persamaan adveksi-difusi. Dari hasil model diketahui pada setiap kondisi pasang surut konsentrasi nitrat pada bagian permukaan perairan Teluk Benoa cenderung tinggi pada daerah bagian barat Teluk Benoa dan timur Teluk Benoa. Sementara pada kolom perairan di Teluk Benoa konsentrasi nitrat cenderung dipengaruhi oleh keadaan elevasi pasang surut. Kondisi nitrat paling tinggi berada pada kondisi surut terendah dan paling rendah berada pada kondisi pasang tertinggi. Konsentrasi nitrat secara vertikal memiliki konsentrasi yang relatif sama.
Kajian Pengembangan Budidaya Ikan Kerapu dan Rumput Laut di Perairan Timur Pulau Serangan
Authors: Sari Septi Novita , Nyoman Nurweda I Dewa , Faiqoh Elok , Giri Putra I Nyoman
Published: September 2019

Aquaculture in Indonesia is able to contribute more than 80% of state money in 2012 contributed USD 5.9 billion. Aquaculture of various commodities has fulfilled the needs of both domestic and international markets. Various areas in Bali have contributed in contributing fisheries production one example is the island of Serangan. Serangan northern island area, has been used as a center for fishery cultivation of floating net floating net (KJA) of Fish and Seaweed in small scale. The main commodities of marine aquaculture in Serangan that are now developed are various types of Ornamental Fish, Sea Horse, Fish Beronang, Grouper Fish and Lobster. In addition to marine aquaculture, seaweed cultivation has grown the region is one type of Euchema cottoni. Current conditions, in the northern Attic has been dense with the existing tourism around the KJA. So that causes the condition of sea traffic in the northern waters is quite crowded so it can affect the cultivation activity. It is known that the income of the community. The biggest and biggest attack is the income from the cultivation fishery. In order to maintain existing cultivation and to meet market needs. So the author aims to examine the study of the suitability of location for the cultivation, especially seaweed and grouper, because the market demand of these two commodities is very high. The expected location of the writer is the eastern area of Serangan. In analyzing the data used scoring system method. The results of this study found that from the three locations of observation, station 1 is quite appropriate for the location of seaweed and grouper cultivation.