bluuebunny/crossref_metadata_2025 huggingface dataset:
ADMINISTRATIVE AND TERRITORIAL REFORM: AGRICULTURAL AGGLOMERATIONS AS THE BASIS OF ADMINISTRATIVE-TERRITORIAL DIVISION
Authors: Yamilov R.M.
Published: October 2022

Agricultural agglomeration processes as the basis of administrative-territorial division are considered. The research of scientists on rural agglomeration processes is analyzed. A critical analysis of existing agglomeration processes has been carried out. The concepts of financially conditioned agglomeration processes and systemically conditioned agglomeration processes are proposed. The inevitable appearance of socially and economically dead territories within the framework of financially conditioned agglomeration processes with the further destruction of existing social groups is shown. The world agglomeration processes, federal agglomeration processes, regional agglomeration processes, municipal agglomeration processes are highlighted. The concept of socio-economic benefits of space is proposed. The possibility of the existence of beneficial social and economic relations with respect to a certain space is shown. The necessity of searching for beneficial social and economic relations to solve the problem of socially and economically dead territories has been established. The main task of the state, society and science is to find the most favorable social and economic relations of this space for the social system as a whole. The possibility of agglomeration of social and economic relations is shown. The concept of the basic territory (space) is given as a space of agricultural production relations, defined through agricultural communication accessibility and agricultural agglomeration processes. The schemes of administrative-territorial reform for the formation of administrative-territorial division in the context of the concept of socio-economic benefits of space are proposed.
EFFECT OF THE BAN ON TURNING TO THE WORST IN THE STAGE OF THE CASSATION PROCEEDINGS IN THE CRIMINAL CASE
Authors: Budylin N.V.
Published: October 2022

Having undergone a number of metamorphoses, the institution of cassation has taken its place in the modern criminal procedure system. This is a system of mixed criminal proceedings, in which the court is traditionally active in establishing the factual circumstances of the case. In principle, the effect of the prohibition on turning for the worse at the stage of cassation proceedings has not changed. The general framework of this prohibition is outlined by law and has a solid foundation - judicial practice and doctrinal provisions. Revision and the prohibition to turn for the worse are part of such a cassation mechanism for verification, which has as its subject not only questions of the legal, but also the factual side of the case. The court of cassation, by virtue of the beginning of the revision, is obliged to identify errors made in the course of criminal proceedings at lower stages. They also include such errors, the correction of which by the court itself or by the lower courts and the preliminary investigation bodies may lead to a transformation for the worse position of the person against whom the final judgment was issued. The system of exceptions to the prohibition on turning for the worse remains, although it has undergone a formal and substantive modification, in particular, instead of sending a criminal case by the court of cassation for a preliminary investigation, there is now a return of the criminal case to the prosecutor. For some points, we can even talk about the strengthening of revision and the weakening of the prohibition on turning for the worse at the stage of cassation proceedings.
Comparison of quantitative and qualita- tive characteristics of the system von Willebrand factor — metalloprotease ADAMTS13 in patients with acute myocardial in farction and is chemic stroke
Authors: Beliaeva E. L. , Koloskov A. V. , Gutkin I. M. , Philippova O. I. , Chernova E. V. , Kurnikova E. A. , Dorofeeva G. B.
Published: October 2022

Introduction. The hemostasis system plays a key role in the pathogenesis of cardiovascular diseases.

Aim — to evaluate changes in quantitative and qualitative characteristics of ADAMTS13 metalloprotease and von Willebrand factor an tigen (vWF:Ag) in patients with acute myocardial in farction (AMI) and is chemic stroke (IS).

Patients and methods. The study in cluded 110 patients aged 42–95 years (median age — 64 years), of which: 65 patients with AMI aged 42–81 years (median age — 56 years) who had coronary artery thrombosis during an giography, as well as 45 patients with IS aged 40–95 years (median age — 70 years) with diagnosed cerebral artery thrombosis. All patients were tested for ADAMTS13 an tigen, ADAMTS13 activity, an tibodies to ADAMTS13 and vWF:Ag. Blood samples were obtained during an giography (arterial and venous blood) and 24 and 120 hours after an giography (venous blood).

Results. In the group of patients with AMI, an in crease in the values of the vWF:Ag in dicator was revealed, which went beyond the upper limit of the reference in terval. In patients with IS, at the beginning of the study, this in dicator was within the reference in terval and was statistically signiﬁcantly lower compared to patients with AMI but in creased after 24 hours and peaked at 120 hours. When an alyzing changes in the ADAMTS13:Ag in dicator, it was found that it was statistically signiﬁcantly higher at all points of the study in the group of patients with AMI, compared with the group of patients with IS, however, the values of this in dicator did not go beyond the reference in terval in patients of both groups. At the same time, the ADAMTS13:AC in dex at all points of the study was statistically signiﬁcantly higher in patients with IS, compared with the group of patients with AMI, and the ADAMTS13:AB in dex. On the contrary, in the group of AMI patients, this in dicator was statistically signiﬁcantly higher in all points of the study when compared with that for the group of patients with IS.

Conclusion. The study of two pathogenetic models of thrombosis demonstrated the absence of a relationship between the vWF:Ag in dex and the quantitative or qualitative characteristics of the ADAMTS13 metalloprotease. At the same time, an in crease in ADAMTS13:AB in AMI can be considered as the reason for the decrease in ADAMTS13:AC in these patients.
Combination of ibrutinib and venetoclax followed by Chimeric Antigen Receptor T-cell therapy in the ﬁrst line of treatment in an elderly patient with mantle cell lymphoma with hyperleukocytosis and mutation in the TP53 gene
Authors: Zvonkov E. E. , Koroleva D. A. , Gabeeva N. G. , Shchekina A. E. , Telyashov M. A. , Aleshina O. A. , Biderman B. V. , Sudarikov A. B. , Obukhova T. N. , Galtseva I. V. , Dvirnik V. N. , Troitskaya V. V. , Galstyan G. M. , Maschan M. A. , Parovichnikova E. N.
Published: October 2022

Introduction. The tactics of therapy for elderly comorbid patients with mantle cell lymphoma with unfavorable prognosis factors (complex karyotype, 17p13 deletion, mutations in the TP53 gene) have not been developed. The use of intensive chemotherapy regimens and transplantation of allogeneic hematopoietic stem cells (allo-HSCT) is impossible due to severe comorbidity in elderly patients. A rational approach is the use of a combination of ibrutinib and venetoclax. As an alternative to allo-HSCT, a new option for elderly patients with poor prognostic factors is Chimeric Antigen Receptor T-cell therapy (CAR-T) cell therapy.

Aim — to present the experience of using ibrutinib and venetoclax with CAR-T-cell therapy in the ﬁrst line of treatment in an elderly patient with MCL with a mutation in the TP53 gene and hyperleukocytosis.

Main ﬁndings. Patient M., 68 years old. The examination revealed hyperleukocytosis 978 × 109/L, anemia (55 g/L), thrombocytopenia (30 × 109/L), and splenomegaly 250 × 180 mm. According to the results of laboratory studies, the diagnosis of lymphoma from mantle cells with a complex karyotype, deletion 17p13, 13q14 and mutation p.R248W in exon 7 of the TP53 gene (VAF = 26 %) was veriﬁed. For cytoreductive purposes, two sessions of leukocytapheresis and prephase with cyclophosphamide (200 mg/m2) and dexamethasone (10 mg/m2) were performed. From day 3, therapy with ibrutinib 420 mg/day and venetoclax 100 mg/day was started. After 2 days, the leukocytes were 0.7 × 109/L, and the size of the spleen decreased, as a result of which the development of tumor lysis syndrome was noted. As a result of intensive therapy, the patient’s condition stabilized, which allowed him to resume treatment. After 7 days, the number of leukocytes was 2.5 × 109/L, neutrophils — 70 %, platelets — 90 × 109/L, hemoglobin — 95 g/L. According to immunophenotyping, the population of B-lymphocytes was 4 %. According to NGS data, the allelic load of the mutation in the TP53 gene is 0.8 %. The patient underwent anti-CD19 CAR-T-cell therapy and achieved complete remission. Three months after therapy, MRD remains-negative remission and the persistence of CAR-T cells is determined.
Lessons Learned in Meaningful Collaboration With Justice Involved Young Adults
Authors: McGinnis Emma , O'Shea Johanna
Published: October 2022

Justice-involved young adults represent the most excluded, stigmatized, and traumatized group amongst their peers and are considered an especially hard-to-reach and hidden population (Case & Haines, 2015; Skinner-Osei et al., 2019). Beresford (2013) highlights how those who face barriers to their involvement in wider society are also more likely to be excluded from participatory arrangements in society. This brief report shares key lessons from a collaborative project between justice-involved young adults and undergraduate social work students, culminating in them collectively producing a learning resource (DVD) articulating the justice-involved young adults’ experiences and needs from professional services.
Shared Purpose: Leveraging a Community-Academic Partnership to Increase Local Environmental Health Awareness via Community Science
Authors: Martin Lisa J. , Hill Vincent , Maples Curtis , Baker Theresa , Elshaer Shereen , Butsch Kovacic Melinda
Published: October 2022

Environmental factors can lead to disease and health disparities when the places where people live, learn, work, play and pray are burdened by social inequities. Non-formal programs that explicitly connect local environmental exposures and human health could be of great value to communities at greatest risk. The purpose of this work was to co-create relevant and engaging education with youth and community stakeholders of all ages that more explicitly emphasizes the link between the local environment and community members’ health through a hands-on community science experience. Our experiences helped strengthen our community-academic partnership and establish a route to create and tailor informal programming to meet local needs and engage people in community science with academic partners. We generated two distinctly different community science neighborhood audit tools designed to differently engage our community partners and inform community participants of their local environments and its role on their health. Through community meetings, we garnered critical insight from our stakeholders. While neither of the tools and accompanying data collected were deemed to be scientifically generalizable, our ongoing and future work has benefited from important lessons learned from their creation and sharing.
Solvent-dependent dispersion stability of PTCDI-C13 nanoparticle colloids made by PLAL
Authors: Jeon Hyeon-Gu , Haramiishi Shuya , Asahi Tsuyoshi , Fujii Masaharu , Ihori Haruo
Published: October 2022

Fabrication of nanoparticle colloids of organic semiconductors is a fascinating subject not only because of its unique properties from the size-effects but also because of its practical advantage of low manufacturing cost for various electronic devices. The detail of its dispersion stability, however, is not studied properly, especially for organic colloids fabricated by pulsed laser ablation in liquid (PLAL) technique. In this study, the primary factor of stabilizing nanoparticles of N,N’-ditridecyl-3,4,9,10-perylenetetracarboxylic diimide (PTCDI-C13) during PLAL is determined by observing the dispersion stability of its colloids prepared in various organic solvents. It is clearly proved that the functional group of solvents is the decisive factor for the dispersion stability of PTCDI-C13 colloids. This result can be applied to other organic semiconductors and promote the advent of a new methodology of organic electronics utilizing highly stable nanoparticle colloids of organic semiconductors for low-cost fabrication of electronic devices.
Physicochemical characteristic and internal browning of pineapple as affected by calcium and gibberellic acid dipping application
Authors: Cano Reinoso Diego Mauricio , Renaldy Tamalea Rafi , Wibowo Condro
Published: October 2022

postharvest applications of Calcium and gibberellic acid have proved to maintain optimal fruit quality and control decay during cold storage. This study evaluated the effect of calcium and gibberellic acid dipping application on pineapple quality and internal browning. The experiment implemented two factors. The first factor concerning two dipping times (five and ten minutes) and the second factor related to four treatments, A (gibberellic acid), B (calcium), C (calcium + gibberellic), and control (D) - (no calcium or gibberellic acid applied). Total soluble solids (TSS), total acidity (TA), TSS/TA ratio, sugar, citric and ascorbic acid content, together with browning severity and incidence, were determined. Treatment B, essentially using a dipping time of five minutes, delivered the best performance having the lowest severity and incidence of browning (4.44 and 22.22 %, respectively), the highest citric acid (0.61 %), ascorbic acid content (405.18 mg kg-1) and TSS/TA ratio (25.53). Meanwhile, the other treatments were considered less satisfactory, due to their highest browning severity and incidence, without remarkable impact on the citric acid and ascorbic acid content, especially with a dipping time of ten minutes. In conclusion, dipping applications of calcium and gibberellic in postharvest enhanced pineapple quality and reduced the internal browning.
Secondary metabolite changes in Maymars juniper cuttings (Juniperus sabina) under different treatments of propagation (IBA, substrate and harvest time of cutting)
Authors: Abshahi Maliheh , Zarei Hossein , Zahedi Bahman , García-Morote Francisco Antonio , Rezaei Nejad Abdolhossein
Published: October 2022

The Endemic Juniper of Maymars (Juniperus sabina) is one of the most valuable plants in forested areas. The objectives of this experiment were: I) to determine the best conditions for stem cutting propagation of this species, and II) to examine changes in some of the secondary metabolites during the four months (the first of each season): January, April, July, and October, after rooting of cuttings. The research was done with the treatment of five levels of Indole Butyric Acid, including: 0, 1000, 2000, 4000, and 8000 ppm in four rooting substrates, including perlite, perlite-cocopeat (1:1), pumice, and a mixed rooting substrate (sand, perlite, cocopeat, vermicompost, and potash; 1:1:1:1:1) in the four seasons of the year, with stem cuttings having an average length of 15 cm. The best treatment with more than 50% rooting was seen in April at levels of 4000 and 1000 ppm, and the best substrate was perlite cocopeat. Using lower levels of IBA led to a reduction in total phenol content in the cuttings during the rooting period. The flavonoid content of the cuttings varied across different seasons. Based on these results, we recommend this way of propagation for Juniperus sabina production. This propagation method takes less time in comparison with sexual propagation from seed.
Academic Music in the Practice of Russian Military Bands in the 19th – Early 21st Centuries
Authors: Zubarev Sergei A.
Published: October 2022

The article is devoted to the theoretical and practical aspects of military musicians’ arrangement practice, considered in the context of developing a system of Russian military orchestras. When studying the socio-cultural foundations of the formation and development of the art of arrangement, factors that reveal the role of Russian composers in the history of military musical culture are highlighted (such works as P.Tchaikovsky’s Skobelev March, A.Rubenstein’s Cavalry Trot are noted). The works of A.Ermolenko (The Evolution of Instrumentation in Russian Wind Music Until the 70s of the 19th Century), G.Salnikov (On the Basic Principles of Transcribing Symphonic Works for a Brass Band), D.Braslavsky (Arrangement for Variety Ensembles and Orchestras), B.Kozhevnikov (Instrumentation for a Brass Band), E.Aksenov (Problems of Theoretical Instrumentation), V.Emelyanov (Instrumentation as an Artistic Factor in Music) were used as fundamental ones to explain this issue. In the process of studying the stages of improving the system of military bands, special attention is paid to studying the features of the development of the military band service in the 19th and 20th centuries. It is noted that several works of academic music performed by military bands belong to this time: the choir and aria from the opera La Sonnambula, the duet from the opera Bianca and Fernando by V.Bellini, the overture, march, choir and a drinking song from the opera Undina by P.Tchaikovsky. In this context, the problems of the formation of the arrangement art are touched upon on the example of A.Alyabyev’s work (the use of orchestral means necessary for a full orchestral sound). When considering the features of the development of military musicians’ arrangement practice in the first half of the 20th century as well as during the collapse of the USSR, attention is paid to the processes of oblivion and revival of the traditions of orchestral wind performance, the emergence of new genres such as the drill show. In this perspective, the activities of famous military bands of the specified period are considered, for example, the Alexandrov Russian Army Song and Dance Ensemble. In conclusion, the author notes that unique conditions for the development of military musicians’ arrangement practice have been created in the national culture, making it possible to preserve the traditions of the military band service and form the value principles of academic art.
Problems of Colour Harmonization of the Composition and the Development of Associative and Imaginative Thinking in the Environmental
Authors: Bogatova Nadezhda P.
Published: October 2022

In the article, the potential of colouristic graphic two-dimensional modeling is revealed on the example of the experience of implementing the Sirius Centre’s program of additional education (Talent and Success Educational Foundation), developed at the Environmental Design Department of the Moscow Stroganov State Academy of Arts and Industry, in order to find solutions for artistic and figurative thematic compositions. The experimental nature of the program involves an interdisciplinary approach to the process of creating a composition at all stages: from conception to sketch and final solution using artistic, musical and literary aesthetics. On the example of the compositional laws of colouristics, the path of ascent to a integral artistic and figurative conception is traced: from the concrete to the abstract, from the pictorial to the expressive, from the emotional to the figurative. The analysis of the performed project and creative works allows us to draw a conclusion about the optimal methodology, technique and format for the implementation of tasks in the framework of training specialists at the early stages of education. The program becomes a contribution to the process of propaedeutic training of a designer in the field of colour plane and volume-spatial modeling.
Frequencies of Failure in The Case of Ceramic Veneer Treatment and the Presence of Composite Fillings: About A Clinical Trial
Authors: Dendouga Soraya , Zeriati Chafika
Published: October 2022

Abstract: Introduction: The restoration of teeth with composite ceramic veneers has always been a subject of controversy: for some authors the presence of such restorations is a source of failure while for others not necessarily. Material and method: Our study; is a randomized clinical trial comparing three types of crown preparations for bonded ceramic veneers. Our clinical trial which evaluated 264 bonded veneers in 73 patients included 235 living teeth and 29 mortified teeth that underwent endodontic treatment. Among the secondary objectives of this study: the evaluation of the durability of ceramic veneers bonded to teeth with composite restorations. Results: The Chi-square test of the occurrence of events according to the unblocked / blocked character gives a p = 0.05 (p ≤ 0.05) so the difference is significant. Conclusion: The presence of composite fillings affected the survival rate of veneers in our study.
Pharmacological, Biopesticide and Post-Harvest Loss Management Application of Jimsonweed (Datura Stramonium)
Authors: Awulachew Melaku Tafese
Published: October 2022

Abstract: Datura stramonium is one of the most intriguing, in part because of its well-known therapeutic and psychoactive properties in the treatment of many diseases. Datura species have been found to exhibit a variety of biological activity. Insecticide, fungicide, antioxidant, antibacterial, hypoglycemic, and immune response boosting properties have been linked to the genus' species. These effects are linked to the existence of secondary metabolites such as terpenoids, flavonoids, with anolides, tannins, phenolic compounds, and tropane alkaloids, which are the most prevalent atropine and scopolamine in the genus Datura. Ingestion of jimson weed produces the toxidrome of anticholinergic intoxication. Understanding and recognizing the classic signs and symptoms of anticholinergic intoxication can help clinicians evaluate persons presenting with jimson weed poisoning. Moreover, this review is to identify the most important phytochemical substances extracted from the jimsonweed and to characterize their biological activity for health effect and biopesticide application. This is because bio-pesticides are less harmful than chemical pesticides because they do not leave harmful residues, generally target one specific pest or a small number of related pests versus broad spectrum chemical pesticides that affect, in addition to the pest, other beneficial insects, birds, mammals, or non-target species, are effective in smaller quantities, decompose quickly and do not cause environmental problems, and are often cheaper than chemical pesticides. In conclusion, Datura stramonium, beside its medicinal value, can applicable for biopesticide application and for post-harvest loss control of insects such as weevil.
A Comparative Study of Safety & Efficacy of Foley’s Induction with Prostaglandin E2 Gel Induction
Authors: Agarwal Dr. Sonalika , Kakani Dr. Pratik K. , Deshpande Dr. Ajit , Deshpande Dr. Mrs. Sarita , Bangal Dr. V. B.
Published: October 2022

Abstract: Background: To compare maternal and fetal outcome with intracervical foley’s catheter and intracervical PGE2 gel on pre-induction cervical ripening for induction of labor. Methods: A Prospective Longitudinal study was carried out in antenatal cases beyond 37 weeks at tertiary care hospital, maharashtra. Pertinent data was collected and analyzed. Results: 50% patients were induced with PGE2 Gel (Group 1) and 50% patients were induced with Foley’s catheter (Group 2). The mean time interval between time of induction and delivery was 14.63±3.42 hours in Group 1 and 15.73±2.20 hours in Group 2. 52 (69.4%) patients in Group 1 had Full Term Normal Delivery (FTND) while 21 (28%) had Lower Segment Caesarean Section (LSCS). 73 (97.4%) patients in Group 2 had FTND while 1 (1.3%) patient had LSCS. The preinduction and postinduction bishops score between the groups was (3.53±0.84 vs. 3.44±0.74) and (6.91±1.24 vs. 7.33±0.83) respectively. Conclusion: Induction with foley’s catheter has significant improvement in Bishop’s score and shorter induction delivery interval as compared to PGE2 gel. Foleys catheter is advantageous as it lacks specific storage condition. It could be considered a cost effective alternative for pre induction cervical ripening.
Dramatic Encounter in Robert Frost’s “Dust of Snow”
Authors: Wang Xueying
Published: October 2022

Robert Frost’s “Dust of Snow” is a marvelous poetic creature of simple and concise language, which conveys complex and profound philosophical insight. This article examines how the dramatic encounter between human and nature in this poem embodies Frost’s perspective on nature and human existence. By depicting the dramatic encounter, Frost reveals the therapeutic power of nature as well as its limitations, and expresses his existential concern on human predicament. The seemingly relaxing but perplexing reading experience generated by this poem, as a sort of dramatic encounter between the readers and the literary text, stimulates the readers to ponder on the vulnerability of both nature and human existence. Thus, Frost activates the dramatic power of poetry and fulfills his duty of enlightening wisdom.
Pengembangan Art Furniture Pada 168 Madura Art Di Yogyakarta
Authors: Faishal Hakim Mochammad
Published: October 2022

Penelitian ini bertujuan untuk mengetahui kemampuan pengembangan art furniture pada 168 madura art di yogyakarta. Penelitian ini merupakan penelitian deskriptif kuantitatif yaitu penelitian yang berusaha untuk menututurkan pemecahan masalah yang ada sekarang dengam menggunakan angka, mulai dari pengumpulan data, penafsiran terhadap data tersebut serta penampilan dari hasilnya. Teknik pengumpulan data yang digunakan dalam penelitian ini menggunakan teknik dokumentasi. Data yamg digunakan adalah data sekunder berupa laporan perkiraan target rugi laba atau r/l tahun 2020 dan laporan realisasi rugi/laba atau r/l tahun 2020 yang membentuk laporan pencapaian perbandingan target dan realisasi rugi/laba atau r/l tahun2020. Setelah melakukan analisis, hasil penelitian menunjukkan ditahun 2020, hasil didapat antara target dan realisasinya untuk laba bersih yang diperoleh ada selisih rp.152.865.005,- - rp.112.612.505,- =rp.40.252.500,-  dari total hasil laporan laba/rugi dalam setahun atau 2020 ( 26,33 % ), realisasi laba bersih diperoleh hanya kisaran 73,667 %. Awal tahun 2020 realisasi laba bersih dari penjualan hanya kisaran 42,2 % dalam tabel 4.6 di antara bulan maret 2020 sampai april 2020, untuk bulan mei 2020 sampai desember 2020 fluktuatif mulai naik realisasinya dari 42,2%. Dari hasil tabel : menunjukkan tahun awal operasional realisasi r/l tahun 2020 dihitung rata rata dari target yang ditetapkan tahun 2020 baru mencapai kisaran 72,98.%.
Generic Structure Of Thesis Abstracts Written By Undergraduate Students
Authors: Malini Nawa
Published: October 2022

Due to a large number of academic information available throughout the world, research abstracts have become extremely important. Abstracts are used by readers to access an article, by journals to pick contributions, by conferences to approve or reject papers (Lores, 2004 as cited in Al-Khasawneh, 2017). Therefore, in this study, the writer would like to analyze the generic structure of a thesis abstract by using Swales & Feak’s (2004) model, namely (1) background, (2) aim, (3) method, (4) results, and (5) conclusion. In order to analyze the genre or generic structure of thesis abstracts, this study uses a qualitative case study approach. Ten (10) English thesis abstracts written by undergraduate students from the English education study program are collected using purposeful random sampling. The researcher sorts the thesis abstracts from the last two years and the theses which have used the quantitative method as their methodology. Findings show that the purpose move (M2), the method move (M3), and the result/finding move (M4) were the most frequent moves that occurred in the abstracts written by undergraduate students enrolled in the English education study program. However, the introduction move (M1) and the conclusion/discussion move (M5) occur less frequently. It could be concluded that the majority of the thesis abstract follows Swales & Feak’s (2004) five-move pattern. While in some thesis abstracts, the move “introduction” and “conclusion” are not included.
Analysis of Factors Affecting Interest in Entrepreneurship Among Adolescents: A Case Study of Students of SMAN 1 Sidoarjo
Authors: Suprayogi Maulana , Sholikhah Ni’matush
Published: October 2022

Most high school graduates are unemployed and unemployment can be reduced by inviting people to open new businesses or entrepreneurship, especially among teenagers. . This study aims to determine the partial and simultaneous effect of self-efficacy, family social support, and entrepreneurial knowledge on students interest in entrepreneurship. By using a sampling technique that is non-random sampling with a population of 116 students. The analysis method uses multiple linear regression analysis with the help of the SPSS 26 program. . The results of this study indicate that there is a partially positive effect of self-efficacy on students' interest in entrepreneurship, there is no partial positive effect of family social support on students' interest in entrepreneurship and there is no partial positive effect of entrepreneurial knowledge on students' interest in entrepreneurship. And simultaneously self-efficacy, family social support, and entrepreneurial knowledge on students' interest in entrepreneurship have a positive effect with a significant value.
Morphological and biochemical changes in the blood and milk of small ruminants infected with brucellosis and treated with Lentinus edodes
Authors:   Voronezh State Agrarian University named after Emperor Peter I, Voronezh, Russia, Polskikh Svetlana V. , Gryzlov Valery A. ,   Voronezh State Agrarian University named after Emperor Peter I, Voronezh, Russia, Ivanov Andrey A. ,   Voronezh State Agrarian University named after Emperor Peter I, Voronezh, Russia, Artemyeva Alina O. ,   Voronezh State Agrarian University named after Emperor Peter I, Voronezh, Russia
Published: October 2022

Brucellosis is among the most dangerous diseases that affect domestic animals, including small ruminants. Therefore, it is necessary to look for ways to improve the physiological state of affected animals. The present study aims to investigate the effect of adding Lentinus edodes mycelium to small ruminant diets on the morphological and biochemical parameters of their blood and milk samples in the presence of brucellosis. The study population includes 5000 sheep with brucellosis, aged 7 months, and consists of three groups: the control group with 1500 animals, the standard treatment (ST) group, also with 1500 animals, and the mycelium-based treatment (MT) group, which includes 2000 animals. Blood samples were collected from each animal four times: at the beginning of the experi-ment, and after 1, 3, 6 months. According to the results, physiological, biochemical, and serological blood parameters returned to normal after 3–6 months in both experimental groups, but the MT group demonstrated faster normalization (p≤0.05); moreover, by the 3rd month of the experiment, animals in the MT group had already recovered from the disease. Based on the present findings, the Lentinus edodes mycelium can be recommended as an effective dietary supplement that can significantly en-hance immunity and help small ruminants with brucellosis recover faster than it is expected with standard treatment.
Study of the wound healing effect of antiseptics based on hydrosols of metal nanoparticles
Authors:   Moscow State Zoological Park, Moscow, Russian Federation, Akulova Svetlana V. , Frolov Georgiy A. ,   MISIS University of Science and Technology, Moscow, Russia, Karasenkov Jacov N. ,   ROSDENT LLC, Moscow, Russia, Deltsov Alexander A. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2022

The article presents the result of a study of the wound-healing effect of hydrosols of metal nanoparticles (silver and zinc) on a plane wound model in laboratory animals. It was found that an antiseptic agent based on zinc oxide nanoparticles promotes faster healing of a planar skin wound in laboratory rats: faster by 4 days compared to 1 control group. On the 17th day of the experiment, the percentage of wound area reduction (PUP) was 96,10 % in control 1, 98,21 % in control 2, 100,0 % in experiment 1, and 98,49 % in experiment 2. Therefore, the results obtained with the use of an antiseptic agent based on silver nanoparticles are consistent with the results obtained with the use of Chlorhexidine containing silver ions in its composition. According to the results of the histological study, it was found that tissue repair occurred in the best way in animals of the 1st experimental group. Compared with other experimental groups, there was practically no inflammatory process.
Clinical, hematological and tomographic characteristics of extrahepatic portosystemic shunts in dogs
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Posyabin Sergey V. , Kek Ksenia A. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Shumakov Nikita I. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2022

The liver performs various biological functions in the body, including removing many toxins from the bloodstream and producing proteins that promote blood clotting. Liver diseases are a common problem in veterinary medicine in small pets. There are several types of vascular abnormalities of the liver, manifested in dogs and cats. The article considers the classification of one of the types of anomalies of the portal venous system – portosystemic shunts (PSS). The statistical data of the most common types of PSS are presented on the basis of their own clinical cases from veterinary practice. Studies were conducted on 30 dogs. It was found that the most common extrahepatic vascular anomalies are: splenocaval PSS – 33 % of cases; splenoazigonal – 30 %; splenophrenal – 17 %; right gastrocaval shunt – 10 %; right gastrocaval shunt with caudal loop – 7 %; right gastroasigonal shunt with caudal loop – 3 %.
Evaluation of the effectiveness holmium laser of lithotripsy in the treatment of dogs with urolithiasis
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Shumakov Nikita I. , Posyabin Sergey V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Tretyakova Dina Yu. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2022

Currently, the main method of treating surgical pathologies of the bladder in animals is the classical method of cystotomy performed using laparotomy, which is characterized by significant trauma and an increased risk of postoperative complications. To reduce the incidence of complications, it is recommended to use minimally invasive surgery methods, such as transurethral cystolithotripsy and laparotomically assisted cystolithotripsy. The authors conducted clinical studies aimed at evaluating the effectiveness of new minimally invasive surgical methods for the treatment of urolithiasis in dogs. One of the methods is lithotripsy, which is carried out using a holmium laser, under the action of which, fragmentation of uroliths occurs and their excretion from the body without the use of any accesses to the bladder. In the article, the authors studied the characteristics and possibilities of using lithotripsy in practice in dogs. Based on the results presented by the authors, one of the significant advantages of transurethral cystolithotripsycan be identified. It is the lack of operative access, which avoids the use of suture material, which can cause complications in the form of fistulas, peritonitis due to the failure of the suture, adhesive disease of the abdominal cavity, as well as incorrect suturing of the bladder wall, salt deposits may form on the suture material, followed by the formation of uroliths.
Investigation of the properties of the hair of the skins of the fox hybrid «bluefrost
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Reusova Tatyana V. , Novikov Mikhail V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Strepetova Oksana A. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: October 2022

Breeding of new types of caged animals is an urgent task of modern fur farming. The skins of fur animals are valued for the diversity of hair color, which is the result of genetic variability due to multiple mutations in the basic color typical of the original wild animal species. Hair color is one of the main breeding traits of great practical importance. Significant economically useful features include the length and thickness of different categories of hair, the evenness of the hairline, depending on the topographical area of the skin of a fur-bearing animal. The skins of the bluefrost fox hybrid, as well as the skins of the silver-black fox and the veil fox, as the hybrid was obtained by crossing them, served as the material for the research. The article presents the results of a study of indicators suitable for identifying the hairline of the skins of the fox hybrid bluefrost, veil fox and silver-black fox. An analysis of the parameters of the hairline is presented: the true length of each category of hair, the thickness of the hair shaft, the pattern and the ratio of the pigment distribution in the shaft of different categories of hair. The studies were carried out in three topographic areas: scruff, rump, and rump.
Index assessment of eliminated ayrshire cows
Authors:   Russian Research Institute of Farm Animal Genetics and Breeding – Branch of the L.K. Ernst Federal Research Center for Animal Husbandry, Tyarlevo village, Russia, Anistenok Sergey V. , Tulinova Olga V. ,   Russian Research Institute of Farm Animal Genetics and Breeding – Branch of the L.K. Ernst Federal Research Center for Animal Husbandry, Tyarlevo village, Russia
Published: October 2022

In a sample of Ayrshire cows (n=14 892), evaluated using the IAYFI selection index, an analysis was made of changes in traits depending on the level of index and the reasons for culling animals (n=11 320). The group with negative values of the IAYFI index (from –2,5 on average) is 63,0 %. The largest number of cows were culled due to Gynecology and infertility (GI) (37,9 %), 19,5 % – Udder (U) and 17,2 % – Legs diseases (L). At the same time, only 2,7 % culled due to Low Productivity (LP), and about 5 % – due to Metabolic Disorders (MD) and Injuries (I). No more than 1 % survived to old age and a little more eliminated as zoodefect. However, in all retirement classes, there is a different distribution of cows depending on the level of milk yield for the 1st lactation (MY1), Productive Life (PL) and IAYFI. Due to LP, most cows with MY1 less than 5000 kg of milk dropped out. According to GI and L, the same number of animals with different levels of milk yield was revealed. U is most susceptible to cows with a milk yield of more than 8000 kg of milk. The share of I and MD grows with the increase in MY. It was found that the most animals with IAYFI levels over +10,0 were eliminated according to GI, although there were fewer of them in disease groups U and L than with IAYFI levels less than +10,0. The eliminated animals in terms of GI, U, and L differ little in terms of MY1, which is at the average level for the sample. Higher MY1 for I and MD, but the former has the lowest PL (1198 days), while the latter have a slightly longer time (1222 days), which is close to those culled by GI. Highly productive cows from MD group are distinguished by low fertility index (FI=45,8), which is comparable with the L group (FI=45,3). Thus, the analysis of the retirement of cows, taking into account their index assessment, revealed weaknesses in the management of the herd. A large number of high-value animals are eliminated by GI, which may be a signal of unsatisfactory conditions for keeping this category of animals, and in the MD group, it may be a consequence of an imbalance in the feed ration.
Features of embryonic development of skeletal muscles in chickens of the breeds Brama and Yurlovskaya golosistaya
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation, Kondratov Gleb V. , Stepanishin Viktor V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation, Oganov Eldiyar O. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation
Published: October 2022

The article presents the histological and morphological characteristics of skeletal muscles (quadriceps femoris and superficial pectoral muscle) in meat (Brama) and egg (Yurlovskaya golosistaya) chickens of productivity on the 14th day of embryonic development: formed muscle fibers combined in bundles, as well as endomysium and perimysium, in the absence of transverse striation. The quadriceps femoral muscle of the Brama breed (meat productivity direction) surpasses the Yurlovskaya golosistaya (egg productivity direction) due to thicker muscle fibers collected in compact bundles and thin connective tissue components. The superficial pectoral muscle has no significant differences in most of the studied micromorphological parameters (thickness of muscle fibers, endomysium, area of muscle tissue and the number of muscle fibers in the field of view) in both breeds of chickens. The exception is the thickness of the bundles of muscle fibers in the superficial pectoral muscle of the Brama compared to the Yurlovskaya golosistaya, as well as a well-developed perimysium. The results obtained are basic in the formation of the concept of histogenesis of skeletal muscles in the embryonic period of development of the organism of poultry of various productivity directions and can be used.
Magnetic-resonance tomography in diagnostic pathologies of neck area of spinal column and spinal cord in dogs
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MBA by K. I. Scriabin, Moscow, Russian Federation, Karaman Viktor S.
Published: October 2022

In the article discusses the effectiveness of using magnetic resonance imaging in the analysis of pathologies of the spinal cord and cervical spine in dogs. It is noted that MRI of the cervical region of PS and SС is widely used in veterinary medicine. The use of a Siemens tomograph with a power of 1.0 Tesla is widely used in practice and this device is quite technologically advanced in the study of spinal cord pathologies using a number of MR programs (MR modes). The modes are described, thanks to which the size of the pathological focus of SС and VP is estimated during preoperative planning. The use of certain MRI technologies allows for effective preoperative planning, if necessary, as well as the prevalence of pathologies in the cervical region of SC and VP in dogs due to their mobility. This serves as a factor of wider distribution due to the high mobility of the cervical region and the greater amplitude of movement of the vertebrae, compared with the thoracic, thoracolumbar and lumbosacral regions of the VP and SC. Thus, these technologies are widely used in veterinary medicine and effectively used in the diagnosis of not only pathologies of VP and SC, as well as the brain, but also other parts of the animal body to detect pathologies, their accurate diagnosis, identify structural changes, the volume of the pathological focus, its spread in the study area and further timely treatment of identified pathologies, using surgical or medical treatment tactics, if necessary.
Morphological composition of meat chickens slaughter products when using an antidiarrheal feed additive in the diet
Authors:   Moscow Veterinary Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation, Petrova Yulia V. , Abramov Pavel N. ,   Moscow Veterinary Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation, Sargsyan Seda A. ,   Moscow Veterinary Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation
Published: October 2022

The article presents the results of a study of the effect of antidiarrheal feed additive «Afluxid®» on the morphological composition of meat chicken slaughter products. It was found that the «Afluxid ®» feed additive used in a dosage of 2,5 g/head per day from the daily age for 7 days and from the 49 day age until the moment of slaughter, most effectively affects the chemical composition of the pectoral and femoral muscles of meat chickens, as well as the histological picture of the muscles and liver of chickens. Increased protein content was observed in meat from chickens of the second group, where it was 20,6 % higher in white muscles and 20,1 % higher in red muscles than in the control group. It was found that when the feed additive «Afluxid®» is introduced into the diet of chickens, the nutritional properties of meat are improved by increasing the protein content, reducing the quantitative representation of fat, compared with the meat of birds that did not receive a feed additive.
Obtaining biologically high-grade egg products when using a feed additive based on protein hydrolysate
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation, Bachinskaya Valentina M. , Deltsov Alexander A. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation, Posyabin Sergey V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation
Published: October 2022

This article presents the results of a study of the amino acid and microelement composition of eggs of laying hens of the egg direction of the Hisex Brown cross when using the Abiotonik feed additive at a dose of 1 ml/kg of body weight every other day. It was found that in the eggs of laying hens of the experimental group, the content of nonessential amino acids increased by 12,3 %, partially nonessential amino acids – by 13,3% and irreplaceable – by 14,7% as compared to the control group. In addition, in the eggs of laying hens of the experimental group, the content of selenium (Se) and iron (Fe) is 59,3 % and 40 % higher, respectively, compared to the control group. As a result of the study of the effect of this feed additive on the egg productivity of laying hens, it was found that the weight of eggs of birds in the experimental group increased by an average of 1,1 g, and egg production over a period of 7 days (44th – 51st days of the experiment) increased by 15 eggs compared to the control group.