bluuebunny/crossref_metadata_2025 huggingface dataset:
Traktat polsko-osmański z Buszy Jarugi (1617) i jego wpływ na międzynarodową sytuację Mołdawii
Authors: Constantinov Valentin
Published: October 2022

Po dramatycznych wydarzeniach 1616 r. Radu Mihnea wstąpił na tron mołdawski. Nowy władca Mołdawii musiał zmierzyć się z trudną misją. Musiał przyczynić się do utrzymania najazdów tatarskich na ziemiach polskich i Kozaków na ziemiach osmańskich. Napięcie między Imperium Osmańskim a Polską osiągnęło szczyt w 1617 roku, kiedy Osmanie postanowili zbudować twierdzę na granicy z Polską. Zamiarowi temu przeciwstawiła się armia polska, gotowa do walki. W kolejnych latach trwały najazdy Tatarów i Kozaków, co przyczyniło się do dalszego pogorszenia stosunków polsko-osmańskich i niestabilności rządów w Mołdawii.
WITHDRAWN: Cannabis Sativa In Phytotherapy : Reappraisal Of Therapeutic
Potential And Regulatory Aspects
Authors: Kohli Kanchan , Gupta Priya , Singh Archu , Shafi Sadat , Ralli Tanya , Pottoo Faheem Hyder
Published: October 2022

The article has been withdrawn at the request of the editor of the journal Current Pharmaceutical Biotechnology.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously
submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere
must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting
the article for publication the authors agree that the publishers have the legal right to take appropriate action against the
authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright
of their article is transferred to the publishers if and when the article is accepted for publication.
Protein PDK4 Interacts with HMGCS2 to Facilitate High Glucoseinduced Myocardial Injuries
Authors: Tan Wenliang , Bao Huogeng , Liu Ziming , Liu Yuanyuan , Hong Lang , Shao Liang
Published: October 2022

Objectives:

As a distinct type of cardiomyopathy, diabetic cardiomyopathy (DCM) is featured as diastolic or systolic cardiac dysfunction in diabetic patients. In order to broaden the understanding of molecular mechanisms in DCM, we intended to explore the mechanism of the interaction between PDK4 protein and Hmgcs2 in high glucose (HG)-induced myocardial damages.

Methods:

PDK4 and Hmgcs2 expression in the myocardium of diabetes mellitus (DM) model rats and HG-incubated cardiomyocyte line H9C2 was analyzed by western blot analysis. Echocardiography and TUNEL assay were utilized for respective assessment of cardiac structure and function and cardiomyocyte apoptosis in DM rats after silencing PDK4 or/and Hmgcs2. In vitro, the impact of PDK4 and Hmgcs2 on HG-induced cardiomyocyte injuries was identified with cell counting kit-8 and flow cytometry assays, along with detection of LDH release, caspase-3/7 activities, and reactive oxygen species (ROS) and malondialdehyde (MDA) levels. Moreover, a coimmunoprecipitation assay was utilized to test the interaction between PDK4 and Hmgcs2.

Results:

Both PDK4 and Hmgcs2 were highly expressed in the myocardial tissues of DM rats. Mechanistically, PDK4 interacted with Hmgcs2 to upregulate Hmgcs2 expression in HG-induced H9C2 cells. Silencing PDK4 improved cardiac function and reduced cardiomyocyte apoptosis in DM rats. In HG-induced H9C2 cells, PDK4 or Hmgcs2 silencing enhanced cell viability and reduced LDH release, caspase-3/7 activities, cell apoptosis, and ROS and MDA levels, and these trends were further promoted by the simultaneous silencing of PDK4 and Hmgcs2.

Conclusions:

In summary, the silencing of PDK4 and Hmgcs2 alleviated HG-induced myocardial injuries through their interaction.
Synthesis, Spectral Characterization, In silico Docking and ADME Prediction
and Biological Evaluation of Novel Piperidin-4-one Derivatives
Authors: Ezhilarasi Muthuvel Ramanathan , Gopalakrishnan Mannathusamy
Published: October 2022

A novel series of 2, 6-diaryl-3-(4-methylpiperazin-1-yl) piperidin-4-one (2a-2f) derivatives were synthesized. All the synthesized compounds were characterized by FT-IR, NMR, Mass spectrum, and CHN analysis. NMR spectral analyses were performed unambiguously by their one-dimensional (1H NMR and 13C NMR) and two-dimensional (1H-1H COSY and 1H-13C HSQC) NMR. From the NMR spectral data, the compounds (2a-2f) were found to have normal chair conformation with an equatorial orientation of all the phenyl groups at C-2 and C-6 and the piperazine ring at C-3. The target compounds 2a-2f were subjected to insilico docking and ADME prediction. From the result of insilico docking study, compound 2d showed a good docking score (-8.2 kcal/mol) compared to the standard drug ciprofloxacin (-7.8 kcal/mol). The synthesized piperidine-4-one compounds (2a-2f) demonstrated good to moderate activity against gram-positive and gram-negative strains. From the result of insilico ADME prediction, most of the compound exhibited good drug score and good drug likeness property.
WITHDRAWN: Overexpression of NR4A2 Alleviates Renal and
Myocardial Injury in Diabetic Nephropathy in Rats Through the HDAC11/
SPRY1 Pathway
Authors: Xu Jia , Li Jinshun , Xu Xiaohui , Zhu He , Zhang Xueli , Yang Mengru , Ren Yeping
Published: October 2022

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been
withdrawn.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php.

BENTHAM SCIENCE DISCLAIMER:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously
submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere
must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting
the article for publication the authors agree that the publishers have the legal right to take appropriate action against the
authors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright
of their article is transferred to the publishers if and when the article is accepted for publication.
A Review on the Synthesis and Pharmacological Activity of
Heterocyclic Compounds
Authors: Baranwal Jyoti , Kushwaha Smriti , Singh Swastika , Jyoti Archana
Published: October 2022

Biologically active compounds play a very important role in our daily life. Almost all the biologically active compounds contain heteroatoms and among these a major portion are heterocycles. Heterocycles are a significant component in drug development programs. Drugs containing a heterocyclic moiety are highly valued resources in the fight against human and animal diseases and disorders. Some of these compounds are utilized as anticonvulsants antivirals, anti-inflammatory, and central vasodilators, while others are used as nontherapeutic anthelmintics, diuretics, anti-hypertensives, uricosurics, fungicides, bactericides, herbicides. In this review, we have discussed the chemistry of heterocyclic compounds such as Quinoxaline, Triazole, Pyrimidine, Pyridine, Oxadiazole, Thiazole, Indole, and Azepine. Besides some of their recent synthetic methodologies, their pharmaceutical importance is also discussed. Undoubtedly, the contents of this review will motivate readers to do more novel work in this area which will accelerate the journey towards the exploration of the pharmacological activity of heterocyclic compounds.
Modal Sosial dalam Keterpilihan Perempuan Calon Gubernur: Studi Kasus Karolin Margret Natassa di Kalimantan Barat dan Khofifah Indar Parawansa di Jawa Timur pada Pilkada Serentak 2018
Authors: Nawang Wungu Dewi Arum
Published: October 2022

This thesis aims to see how social capital is utilized in the process of selecting female gubernatorial candidates in the 2018 election. The research subjects were Karolin Margret Natassa of West Kalimantan and Khofifah Indar Parawansa of East Java. This phenomenon needs to be studied through a constructive paradigm, to find out how these two women formed and used their social capital to win as governors, a position that has rarely been filled by women since the direct local election era began. A social capital analysis is placed at the micro (individual) level in the structural (network) dimension using the Social Capital theory of Pierre Bourdieu and Robert Putnam. This research also wanting to identifies what kind of political pathways lead women into political contestation, and how it can affect the instrumentalization pattern of their social capital. The research procedure was carried out using qualitative methods where data collection was carried out through in-depth interviews with key informants and then deepened by literature studies. The results showed that Karolin and Khofifah have different types of social network ties in the process of utilizing their social capital. Karolin is a Bonding type (Same identity with strong ties characteristic and more focusing on internal traits), while Khofifah is a Bridging and Linking type, where the earned trust is used to bridge the interests of groups and later to be activated as a ladder to her political interests. The results of the study also identified Karolin as a politician from the elite route and Khofifah as a politician from the grassroots route.
The half-metallic properties of Heusler alloys Mn-=SUB=-2-=/SUB=-ScZ (Z=Al, Si, P, Ga, Ge, As, In, Sn, Sb): ab initio study
Authors: Baigutlin D. R.  , Sokolovskiy V. V.  , Miroshkina O. N.  , Buchelnikov V. D.
Published: October 2022

The properties of Heusler alloys of the Mn2ScZ family (Z=Al, Si, P, Ga, Ge, As, In, Sn, Sb) are investigated within the framework of the density functional theory. The PBE GGA and meta-GGA SCAN functionals were used for approximation of the exchange-correlation interactions. Calculations show that PBE does not predict ideal half-metallic behavior, unlike SCAN. It is shown that at Z=P, Si, a transition from the half-metallic state to the metallic one is observed. This effect can be used to develop tunable spintronic devices. Keywords: exchange-correlation functional, meta-GGA SCAN, half-metal ferromagnets, Heusler alloys.
Features of the pulsed cathodoluminescence kinetics of neodymium ion in yttrium-aluminum garnet and yttria
Authors: Solomonov V. I.  , Spirina A. V.  , Makarova A. S.
Published: October 2022

The kinetics of pulsed cathodoluminescence of Nd3+ ions in single crystals, ceramics, and nanopowders of Nd3+ : Y3Al5O12 (Nd3+ : YAG) and Nd3+ : Y2O3 under excitation by a 2 ns electron beam with average electron energies of 130, 150, and 170 keV was studied. In this case, the luminescence of these substances occurs after the termination of the electron beam. In Nd3+ : YAG, there are optical transitions from the 2F25/2 level of the neodymium ion in the ultraviolet and visible regions of the spectrum, as well as from the 4F3/2 level in the near infrared region. In Nd3+ : Y2O3, there are not transitions from the 2F25/2 level of the neodymium ion, but infrared luminescence occurs from the 4F5/2 and 4F3/2 levels. The luminescence kinetics is characterized by rise and decay and it is described by the difference of two exponential functions. It is found that the characteristic luminescence decay times are the lifetimes of the 2F25/2, 4F5/2 and 4F3/2 emissive levels, and the rise time is determined by their pumping in recombination and relaxation processes. The rise mechanisms of pulsed cathodoluminescence are substantially different from the mechanisms of "phosphor ignition", which occur during ionization and excitation of the phosphor by an external source. Keywords: pulsed cathodoluminescence, neodymium ion, yttrium-aluminum garnet, yttria, kinetics, rise time, decay time.
Features of polarization of piezoelectric ceramics based on sodium niobate
Authors: Malyshkina O.V.  , Ali M.  , Ivanova A.I.  , Chernyshova I.A.  , Mamaev D.V.
Published: October 2022

Comparative studies of the pyroelectric properties and structural features of sodium niobate and sodium-potassium niobate ceramics obtained under different technological conditions for the synthesis of sodium niobate have been carried out. X-ray phase analysis revealed the existence of an additional phase with the chemical formula NaNb10O18 in sodium niobate ceramic samples that do not exhibit ferroelectric properties. It is shown that the temperature conditions for the synthesis of the sodium niobate material determine the nature of the macroscopic polarization of the samples of both pure sodium niobate and sodium-potassium niobate. Keywords: piezoelectric ceramics, lead-free materials, polarization, pyroelectric effect.
Effect of the defectiveness of the carbon sublattice on the elastic properties of cubic titanium carbide TiC-=SUB=-y-=/SUB=-
Authors: Gusev A. I.
Published: October 2022

Changes in the elastic constants cij of disordered cubic titanium carbide TiCy with an increasing the defectiveness of the carbon sublattice are estimated for the first time. It was found that the deviation of titanium carbide from the stoichiometric composition TiC1.0 leads to a decrease in the elastic stiffness constants cij of disordered TiCy carbide with a simultaneous increase in elastic anisotropy. The distributions of Young's modulus E and Poisson's ratio μ in the (100) plane and the distributions of the shear modulus G in the (100), (110), and (111) planes have been calculated as functions on the crystallographic direction [hkl] and on the relative carbon content y in TiCy carbide. The lowest values of the shear modulus Ghkl for TiCy are observed in the (111) plane. Keywords: Titanium carbide, Nonstoichiometry, Vacancies, Elastic properties.
Calculation of the dynamics of the amorphous phase-crystal interface during solid-phase explosive crystallization
Authors: Chevrychkina A. A.  , Bessonov N. M.  , Korzhenevskii A. L.
Published: October 2022

The nonlinear differential equation described a dynamics of solid-phase explosive crystallization front in a much larger parameters domain in comparison with the theoretical results available in literature was obtained. The features of the self-oscillating mode transition of the front motion to the mode of its self-propagation with a constant velocity was numerically studied in detail. Ketwords: Explosive crystallization, self-oscillations of the interface glass-crystal, self-propagating front.
Preventing Revictimization Through a Web-Based Intervention for Primary Caregivers of Youth in Care (EMPOWERYOU): Protocol for a Randomized Factorial Trial
Authors: Heinrichs Nina , Brühl Antonia
Published: October 2022

Background

Children in foster care are at a higher risk for relationship problems than their counterparts raised by their biological family because of higher exposure to or prevalence of neglect or maltreatment early in life. Consequently, these children may also show more challenging behavior in their foster families, which in turn increases the parental stress experience of foster caregivers. Furthermore, the children may engage in a vicious cycle of risky relationship behaviors and expectations that put them at a greater risk for revictimization.

Objective

To support foster caregivers in reducing the risk for revictimization, several intervention modules delivered via the internet were developed using a consumer-based approach (phase 1 of the multiphase optimization strategy). This project (phase 2 of the multiphase optimization strategy) aimed to develop a sustainable intervention by selecting promising intervention components based on their contribution to the outcome.

Methods

In a 24 factorial trial, a total of 317 foster caregivers with children aged 8 to 13 years are randomly assigned to 1 of 16 conditions. The primary outcome is the rate of revictimization from baseline to 3 months after intervention. Secondary outcomes include risk-taking and functional behaviors in relationships. All caregivers will receive access to all the intervention components after the follow-up assessment. The participants assigned to the condition with all component levels on are expected to show the best improvement in the primary and secondary outcomes.

Results

Recruitment and data collection for the factorial trial started in March 2022 and is ongoing. As of October 2022, we recruited 181 families. Although it is difficult to predict the exact study timeline owing to COVID-19 pandemic–related delays, results are expected in February 2024.

Conclusions

There is a need for easily accessible information related to raising children in foster care who have experienced early life adversities to interrupt the cycle of violence and enhance the developmental pathway of health and emotional stability. It might be useful, in addition to generally useful parenting information (eg, parental self-care or emotion regulation management), to specifically focus on the needs of these caregivers (eg, how to support the child to reduce dysfunctional relationship behaviors that may have developed because of early adverse experiences).

Trial Registration

ClinicalTrials.gov NCT05235659; https://clinicaltrials.gov/ct2/show/NCT05235659

International Registered Report Identifier (IRRID)

DERR1-10.2196/38183
The Association of Midday Napping With Hypertension Among Chinese Adults Older Than 45 Years: Cross-sectional Study
Authors: Tang Dongfeng , Zhou Yiheng , Long Chengxu , Tang Shangfeng
Published: October 2022

Background

Hypertension is one of the main public health issues around worldwide, and midday napping is a popular habit. The association between the two remains to be explored.

Objective

The goal of the research was to explore the association of midday napping with hypertension.

Methods

This study separately selected 11,439, 12,689, and 9464 Chinese respondents aged over 45 years from the China Health and Retirement Longitudinal Study 2011, 2015, and 2018 data sets. Binary logistic regression was used to explore the association of midday napping with hypertension, and the 3-step method was used to test the mediation effect of BMI.

Results

Among all respondents, the prevalence rates of hypertension were 24.6% (2818/11439) in 2011, 21.1% (2683/12689) in 2015, and 22.1% (2092/9464) in 2018. Midday napping was positively correlated with hypertension. In 2011 and 2015, napping 60 to 90 minutes had the greatest odds ratios [OR] (OR2011 1.705, OR2015 1.494). In 2018, the biggest OR came from the group napping 30 to 60 minutes (OR 1.223), and ORs of different napping durations decreased from 2011 to 2018. In addition, BMI had a partial mediation effect in 2015 and 2018.

Conclusions

Midday napping is a potential risk factor for hypertension with BMI acting as a mediator. To prevent hypertension, avoiding prolonged duration of midday napping and taking action to maintain a normal BMI level are recommended.
The Effects of the Use of Patient-Accessible Electronic Health Record Portals on Cancer Survivors’ Health Outcomes: Cross-sectional Survey Study
Authors: Liu Piper Liping , Zhao Xinshu , Ye Jizhou Francis
Published: October 2022

Background

In the past decade, patient-accessible electronic health record (PAEHR) systems have emerged as an important tool for health management both at the hospital level and individual level. However, little is known about the effects of PAEHR portals on the survivorship of patients with chronic health conditions (eg, cancer).

Objective

This study aims to investigate the effects of the use of PAEHR portals on cancer survivors’ health outcomes and to examine the mediation pathways through patient-centered communication (PCC) and health self-efficacy.

Methods

Data for this study were derived from the Health Information National Trends Survey (HINTS 5, Cycle 4) collected from February 2020 to June 2020. This study only involved respondents who reported having been diagnosed with cancer (N=626). Descriptive analyses were performed, and the mediation models were tested using Model 6 from the SPSS macro PROCESS. Statistically significant relationships among PAEHR portal use, PCC, health self-efficacy, and physical and psychological health were examined using bootstrapping procedures. In this study, we referred to the regression coefficients generated by min-max normalization as percentage coefficients (bp). The 95% bootstrapped CIs were used with 10,000 resamplings.

Results

No positive direct associations between PAEHR portal use and cancer survivors’ health outcomes were found. The results supported the indirect relationship between PAEHR portal use and cancer survivors’ psychological health via (1) PCC (bp=0.029; β=.023, 95% CI .009-.054), and (2) PCC and health self-efficacy in sequence (bp=0.006; β=.005, 95% CI .002-.014). Besides, the indirect association between PAEHR portal use and cancer survivors’ physical health (bp=0.006; β=.004, 95% CI .002-.018) via sequential mediators of PCC and health self-efficacy was also statistically acknowledged.

Conclusions

This study offers empirical evidence about the significant role of PAEHR portals in delivering PCC, improving health self-efficacy, and ultimately contributing to cancer survivors’ physical and psychological health.
The Impact of an Electronic Portal on Patient Encounters in Primary Care: An Interrupted Time-Series Analysis (Preprint)
Authors: Ferguson Karen , Fraser Mark , Tuna Meltem , Bruntz Charles , Dahrouge Simone
Published: October 2022

BACKGROUND

Electronic patient portals are online applications that allow patients access to their own health information, a form of asynchronous virtual care. The long-term impact of portals on the usage of traditional primary care services is unclear, but is an important question at this juncture when portals are being incorporated into many primary care practices.

OBJECTIVE

We sought to investigate how an electronic patient portal affects traditional, synchronous, primary care health care usage over a much longer time period than any existing studies, and to assess the impact of portal messaging on the clinician’s workload.

METHODS

We conducted a propensity-score-matched, open-cohort interrupted time series evaluation of a primary care portal from its implementation in 2010. We extracted information from the EMR regarding age, sex, education, income, family health team enrolment, diagnoses at index date, and number of medications prescribed in the previous year. We also extracted the annual number of encounters for up to 8 years pre and post index date as well as provider time spent on secure messaging through the portal.

RESULTS

7247 eligible portal patients and 7647 eligible potential controls were identified, with 3696 patients matched one to one. We found that portal registration was associated with an increase in the number of certain traditional encounters over the time period surrounding portal registration. Following the index year, there was a significant jump in visits to physicians in the portal arm (0.42 higher than control, P<0.001) but not for visits to nurse practitioners and physician assistants. The calls to the practice triage nurses also showed a greater increase the portal arm compared to the control arm after the index year (an additional 0.102, P=0.0056). The average provider time spent on portal-related work was 5.7 minutes per patient per year.

CONCLUSIONS

We found that portal registration was associated with a subsequent increase in the number of some traditional encounters and a small increase in clerical workload for providers. Portals have enormous potential to truly engage patients as partners in their own health care, but their impact on usage of traditional health care services and clerical burden must also be considered when they are incorporated into primary care.
Pemetaan Ekosistem Teknologi Digital untuk Membantu Penanganan Covid-19 di Daerah Istimewa Yogyakarta dan Daerah Khusus Ibukota Jakarta
Authors: Adiwibowo Insan Rekso
Published: October 2022

ABSTRAKLatar Belakang: Terjadinya lonjakan pasien COVID-19 berakibat pada kelebihan beban Rumah Sakit dan kekurangan logistik medis, banyak institusi baik dari sektor publik maupun swasta bekerja secara cepat mengembangkan infrastruktur teknologi informasi pendukung baik dalam bentuk laman web, aplikasi, ataupun perangkat-perangkat teknologi digital lainnya. Namun upaya-upaya tersebut seringkali tidak terkoordinasi baik antara lembaga kepemerintahan, upaya sektor publik dan sektor swasta/masyarakat. Hal ini mengakibatkan terjadinya asimetri dan fragmentasi informasi di mana informasi berada pada lokus-lokus eksklusif dan hanya digunakan oleh institusi atau komunitas tertentu. Untuk mewujudkan sinergi tersebut dibutuhkan adanya pemetaan keberadaan dan kebutuhan teknologi digital. Tujuan: melakukan pemetaan lanskap inisiatif teknologi informasi pendukung COVID-19 di DKI Jakarta dan DI Yogyakarta dan mengidentifikasi gap yang belum terjembatani antara usaha yang dilakukan pemerintah dan sektor swasta untuk membantu persiapan surge capacity rumah sakitMetode Penelitian: Penelitian ini menggunakan pendekatan kualitatif dengan model analisis dokumentasi. Dalam penelitian ini dokumen yang diselidiki adalah dokumentasi-dokumentasi yang tersedia dalam website atau aplikasi inovasi teknologi digital, kebijakan, himbauan, berita, dan lain sebagainya baik dalam bentuk tertulis maupun audio/visual. Hasil: Terdapat 26 aplikasi dan 7 website terkait COVID-19 di Indonesia. Aplikasi dan/atau website yang dipetakan menjadi dua kategori, yaitu publik dan non-publik. Kategori publik merupakan aplikasi dan/atau website yang dapat digunakan oleh masyarakat umum dan tidak memerlukan akses khusus. Sedangkan kategori non publik adalah untuk aplikasi dan/atau website yang hanya bisa digunakan oleh pihak-pihak tertentu saja dan memerlukan akses khusus, keberadaan informasi dari kategori non publik ini bersifat rahasia. Terdapat 32 temuan aplikasi/website untuk kategori publik dan 4 temuan untuk kategori non-publik.Kesimpulan: Pemerintah Daerah DIY (bersama dengan para penggiat TI di DIY) telah membuat berbagai teknologi informasi dalam menangani pandemi COVID-19 (khusus untuk DIY) masih terdapat beberapa tantangan yaitu berkaitan dengan contact tracing, data sharing yang dapat dimanfaatkan oleh pihak lain yang menjadi teknologi yang paling dibutuhkan saat ini. misal para stakeholder, akademisi (peneliti), masyarakat, dan perlunya regulasi dari pemerintah pusat/daerah terkait pengelolaan teknologi informasi agar data dapat dimanfaatkan oleh berbagai pihak terkait untuk membantu mengatasi pandemi COVID-19.Kata Kunci: e-Health, Pemetaan Teknologi Digital, Covid-19
HIS Implementation in Small Hospital
Authors: Perwirani Resia
Published: October 2022

Background: Budi Rahayu Hospital at Magelang City has implemented HIS in partnership with the SIMKES FKKMK laboratory of Gadjah Mada University since April 2021. During the initial four months of implementation, Budi Rahayu Hospital experienced various challenges. For understanding and overcome the challenges, it is necessary to construct a strategy of HIS implementation, and then offer a proper recommendation based on study.Methods: This study is a descriptive qualitative with action research design that describe four stages of action research i.e Diagnosing, Planning, Action, and Evaluation. On the Diagnosing stage, Author arrange an interview and discussion with Hospital Team. Next, Author plan a strategy to generate suitable recommendations for the successful implementation of HIS. In the Action stage, author conduct an implementation review and assistance. Author also manage an UAT as a evaluation stage distributed to respondents using a questionnaire. The study is performed by observing of HIS implementation from September – December 2021. The subject of this study is chosen purposively from departments involved, with total 20 end-users respondents on multiple service units to capture data in a real environtment when HIS is used for healthcare services to patients.Results: Strategic actions for smooth implementation is active involvements and collaboration from developer team and hospital team monitored by regional health services. the hospital team and developer team formed an online communication group as a place to discuss the problems encountered. There are monitoring activities that involved by regional health services, so the timeline that has been set runs according to the target and the hospital gets optimal benefits of HIS implementation. System acceptance is important for the further development of  HIS. The score of HIS acceptance at Budi Rahayu Hospital is 70% based on 85% scenario that execute successfully. Based on system performance, continues maintenance and communication among implementation team, HIS can be accepted with condition of continuous improvement and adjustment.Conclusions: Active involvements and collaboration from developer team and hospital team, performance improvement and availability of the system is very crucial for user acceptance, satisfaction and overall success of HIS implementation. Keywords: HIS, Implementation, UAT
Factores que inciden en la conducta de compra de productos agroecológicos en Mérida, Yucatán, México
Authors: Bojórquez Carrillo Ana Laura , Flores Anel , Hernández Islas Mireya Noemí , Ortiz Medina Imelda
Published: October 2022

Objetivo: analizar los motivadores, las barreras y los factores sociodemográficos que inciden en la compra de productos agroecológicos y la relación que existe entre estas variables. El conocimiento de los motivadores y barreras que inciden en la compra de estos productos repercute en los planes y estrategias de mercadotecnia, principalmente de tipo social.  
Diseño metodológico: el enfoque de este estudio es cuantitativo, correlacional y transversal. La recopilación de la información se realizó a través de la aplicación de 719 encuestas a clientes potenciales de productos agroecológicos. Los métodos de análisis de la información empleados fueron la estadística descriptiva y la estadística no paramétrica, efectuando pruebas de independencia Chi a partir de las tablas de contingencia cuadrado correspondientes y la obtención de los coeficientes de correlación de Spearman, Tau b de Kendall, y un modelo de regresión logística binaria.   
Limitaciones: el trabajo de campo se hizo en el mes de noviembre de 2021, tiempo en el que había restricciones de movilidad impuestas por la pandemia COVID-19, lo que resultó en una alta tasa de rechazo para efectuar las entrevistas personales que se requirieron, por lo que, a pesar de haber logrado la muestra, esta situación puedo haber afectado la representatividad.   
Hallazgos: los resultados demuestran que, si el comprador tiene la motivación para contribuir con el medio ambiente o para convertirse en un consumidor responsable es más probable que tenga una alta frecuencia de compra de productos agroecológicos. Asimismo, se observaron los siguientes resultados: a mayor edad de los clientes potenciales, mayor frecuencia de compra; a menor edad de los clientes potenciales, más motivación tienen para elegir los productos agroecológicos si tienen un buen sabor, entre otros.
Telesimulación como estrategia de enseñanza aprendizaje en estudiantes de Nutrición durante la pandemia COVID-19
Authors: Trunce Morales Silvana Trinidad , Villarroel Quinchalef Gloria Del Pilar , García Alvarado Katherine Isabel
Published: October 2022

Introducción: Debido a la pandemia COVID-19, la docencia universitaria tuvo que adaptar la enseñanza tradicional a la educación remota de emergencia, buscando la mejor manera de dar cumplimiento al perfil de egreso. En la carrera de Nutrición y Dietética de una universidad pública del sur de Chile, se utilizó la herramienta de telesimulación en la asignatura de Dietoterapia del Adulto II, dictada en el séptimo semestre.

Objetivo: Determinar la calidad y satisfacción de los estudiantes de la carrera de Nutrición y Dietética al utilizar la telesimulación clínica como método de enseñanza y aprendizaje en la asignatura de Dietoterapia del Adulto II, durante la pandemia COVID-19.

Método: El diseño de la investigación es cuantitativo, exploratorio, no experimental, descriptivo y de corte transversal, con una muestra no probabilística de 42 estudiantes que cumplieron con los criterios de inclusión. La telesimulación aplicada fue protocolizada, posteriormente se aplicó a los estudiantes la encuesta de calidad y satisfacción de simulación clínica y una autoevaluación. Los datos estadísticos fueron procesados y se trabajó el análisis estadístico descriptivo, las respuestas de la pregunta abierta fueron analizadas cualitativamente. Los aspectos éticos de la investigación fueron resguardados según los principios éticos de la declaración de Helsinki.

Resultados: en relación a la encuesta calidad y satisfacción en simulación clínica, reportaron una alta satisfacción, con un 75.87% de respuestas “muy de acuerdo”. La telesimulación fue asociada a los conceptos de aprendizaje, competencia, fortaleza y emociones.

Conclusiones: La telesimulación es una estrategia eficiente mediante la cual se pueden integrar los conocimientos teóricos y prácticos en un ambiente de aprendizaje controlado, favoreciendo el logro de competencias. Se propone que esta estrategia sea incorporada para la evaluación del resultado de aprendizaje final de las asignaturas.
Calidad de los casos de aprendizaje basado en problemas empleados en educación fisioterapéutica
Authors: Tejeda Castellanos Xochiquetzalli , Alpuche Hernández Amilcar , Aburto-Arciniega Mónica Beatriz , Gutiérrez Camacho Claudia
Published: October 2022

Introducción: El aprendizaje basado en problemas (ABP) es una de las metodologías de enseñanza utilizadas en la formación de profesionales de la salud, en la cual los estudiantes son expuestos a la resolución de casos clínicos para lograr los objetivos educativos; sin embargo, la evidencia sobre la calidad de los casos en la enseñanza de los fisioterapeutas es escasa.

Objetivo: Evaluar la calidad de cuatro casos clínicos empleados en la enseñanza de la fisioterapia con base en la opinión de los estudiantes y profesores.

Método: Estudio transversal analítico que evaluó, a través de un instrumento validado, la calidad del contenido y estructura de cuatro casos utilizados por los estudiantes de la licenciatura en fisioterapia de la Universidad Nacional Autónoma de México.

Resultados: El instrumento no se comportó igual en los estudiantes y en los profesores, los estudiantes identificaron un factor para los cuatro casos, mientras que los profesores identificaron dos factores relacionados con habilidades de aprendizaje y conocimiento previo. El puntaje global de cumplimiento de las características fue mayor a cuatro, tanto en estudiantes como en profesores, ya que los consideraron de buena calidad.

Conclusiones: La opinión de profesores y alumnos aporta información valiosa sobre la utilidad de los casos clínicos; sin embargo, resulta relevante considerar la evaluación objetiva del desempeño de los estudiantes en la práctica real.
Validación de un cuestionario para evaluar el sentido de pertenencia en médicos residentes
Authors: Pacheco-Zavala Ma. Del Pilar , Hernández-Ordóñez Raúl , Rojas Rendón Itzel Alejandra
Published: October 2022

Introducción: El sentido de pertenencia se define como la representación que tenemos de nosotros mismos, sentimiento de identificación y vinculación como consecuencia de estar incluidos con un grupo y el ambiente donde se desarrolla, con la construcción de significados propios.

Objetivo: Identificar si el instrumento es válido para evaluar el sentido de pertenencia en los médicos residentes.

Método: Se realizó un estudio transversal descriptivo para la adaptación del cuestionario del sentido de pertenencia al área médica. Para la validez de contenido se empleó el método Delphi, con la colaboración 5 expertos; la prueba piloto se aplicó en 101 residentes, mientras que la validez de constructo y confiabilidad se determinaron mediante el análisis factorial exploratorio (AFE) y el coeficiente de alfa de Cronbach respectivamente. La investigación fue autorizada por el comité de ética en investigación no.10088, y comité local de investigación en salud No.1008 del IMSS. Todos los participantes firmaron el consentimiento informado.

Resultados: Se realizaron 2 rondas de expertos para considerar el cuestionario válido; el coeficiente de alfa de Cronbach global fue de 0.97 y >0.90 por cada uno de sus apartados. Mediante el AFE se identificó una estructura de 4 factores, con una medida de adecuación KMO de 0.885, prueba de esfericidad de Bartlett <0.05 y una correlación entre las variables >0.6. El cuestionario quedó conformado por 19 ítems, agrupados en 4 factores: afectivos, psicológico-sociales, académicos y físicos. La varianza total explicada se manifiesta con los primeros 4 factores con 65.31%.

Conclusiones: La adaptación del cuestionario de sentido de pertenencia de la PUCMM-CSTA al área médica muestra una buena psicometría, por lo que se considera válido y confiable para evaluar el sentido de pertenencia en los alumnos de los cursos de especialización médica.
El valor p: ¿cómo analizarlo para separarse del positivismo extremo e inductivismo ingenuo?
Authors: Padilla-Santamaría Fernando
Published: October 2022

A pesar de las nuevas reflexiones y corrientes ideológicas en las ciencias médicas, muchos investigadores continúan apegados firmemente al positivismo científico, al inductivismo ingenuo y a miradas totalmente reduccionistas, donde el uso de estadística inferencial se considera casi indispensable para juzgar una investigación “de calidad”, y dentro de ella, estimar al famoso valor p como el número que determina que un estudio es “bueno” o “malo”, que vale la pena o no, que salió “bien” o “mal”. Aunque la estadística inferencial es la más frecuente en las ciencias médicas, muchos investigadores continúan con problemas epistemológicos para la interpretación del valor p y la toma de decisiones estadísticas; por ello, el objetivo principal de este trabajo es brindar una reflexión y análisis dinámico de qué es, cómo se obtiene, cómo suele interpretarse y cómo debería interpretarse el valor p.

Cabe destacar que este escrito no pretende enseñar estadística, sino que intenta cambiar la forma en que los estudiantes y profesionales de la salud interpretan la estadística inferencial, con el fin de fomentar la lectura crítica y de esta forma dar armas para el aprendizaje autodidacta. Para llegar al adecuado análisis del valor p, a lo largo del trabajo realizo un repaso general y gráfico acerca de la construcción de hipótesis, la distribución normal y las pruebas de hipótesis.

Si bien por el simple hecho de que este trabajo hable de estadística inferencial ya lo convierte (hasta cierto punto) en un artículo positivista, deseo que la nueva enseñanza en esta área permita formar nuevos profesionales e investigadores con visiones más amplias de la investigación, y así terminar con el fomento del reduccionismo e inductivismo ingenuo.
LA M’INKA, EL AYNI Y EL APACHIKUY: PRACTICAS SOCIALES PARA SISTEMAS ALIMENTARIOS EN CRISIS
Authors: Meza Flores Liza Melina , Heindorf Claudia
Published: October 2022

Las prácticas sociales andinas, como la mink’a, ayni y apachikuy se basan en la solidaridad, que busca garantizar la producción y consumo de alimentos para las personas en el campo y también para sus familiares en las ciudades. El entretejido el conocimiento tradicional y prácticas sociales, así como innovaciones pueden resultar eficaz para promover la resiliencia de los sistemas alimentarios. El objetivo de nuestro trabajo es dar a conocer las prácticas sociales de cooperación para la producción (mink’a y ayni) y distribución de productos (apachikuy) como ejemplos de prácticas que son relevantes en Perú, y discutir su práctica actual y potencial para afrontar las crisis alimentarias.  Para lograrlo, se han realizado entrevistas semi-estructuradas a diferentes actores y una revisión de literatura. Con base a esta información se ha realizado un análisis FODA (Fortalezas, Oportunidades, Debilidades y Amenazas). Nuestro análisis resalta las fortalezas y oportunidades para la contribución a los tejidos sociales y el apoyo a los grupos vulnerables, y revela las debilidades y amenazas relacionadas al abandono y devaluación de estas prácticas sociales. Concluimos, que estas prácticas sociales contribuyen a sostener los sistemas alimentarios en situaciones críticas, pero se requieren programas e investigaciones para asegurar su continuidad y promover su revitalización y reactivación.
Hybrid studies in medicine and public health
Authors: Kholmatova K. K. , Kharkova O. A. , Gorbatova M. A. , Grjibovski A. M.
Published: October 2022

In this paper we present an overview of the two main types of hybrid (combined) studies — nested case-control studies and case-cohort studies. Main research questions that can be addressed using these study designs are presented. The methodological features of nested case-control and case-cohort studies as well as their strengths and limitations are described in detail. Moreover, we present how to interpret the results of these studies and give examples from the international peer-reviewed literature.
Industrial healthcare in the Russian Arctic - trends and experience of recent decades
Authors: Logunov K. V. , Antipov S. A. , Lepetinsky I. S. , Karpov A. B.
Published: October 2022

The results of medical care with employees of remote offshore and industrial facilities in oil and gas production in the Russian North are presented over the past two decades. Best practices, providing maximum efficiency, including risk assessment and management, emergency planning, telemedicine, staff training in basic medical concepts and first aid, formation and maintenance of staff health registers. Each of the areas significantly improved medical statistics.
Seasonal dynamics in functional state of nervous system among skiers of the military age based on visual-motor response: cohort study
Authors: Masko E. V. , Mosyagin I. G. , Boyko I. M.
Published: October 2022

INTRODUCTION: Athlete’s training activity in conditions of the European North involves severe physical exertion in extreme climatic conditions. In this case emerging physiological and meteopathic reactions might have a negative impact on the functional state of persons of military age.

OBJECTIVE: Identify the characteristics of seasonal changes in the state of nervous system among skiers of the military age.

MATERIALS AND METHODS: 20 skiers of the military age took part in the study. It was carries out over a year and included 4 stages, complying with the stages of athletes’ preparation. During the work by means of the device «Psychophysiologist» there was recording indicators of mean, minimum and mean-square deviation of time of simple and complex visual-motor reaction and also the duration of cardiointervals. Statistics: Statistical software package SPSS 20.0 was used for analyzing the results.

RESULTS: As a result of the study, it was found that the skiers experience deterioration of visual-motor reaction with the increasing impact of training activities and negative factors of the north.

CONCLUSION: Functioning of the athlete’s body in conditions of the European North leads to deterioration of indicators of nervous system activation level and capacity in the winter training period.
Classically Replaceable Operations
Authors: Liu Guoding , Zhang Xingjian , Ma Xiongfeng
Published: October 2022

Quantum information science provides powerful technologies beyond the scope of classical physics. In practice, accurate control of quantum operations is a challenging task with current quantum devices. The implementation of high fidelity and multi-qubit quantum operations consumes massive resources and requires complicated hardware design to fight against noise. An approach to alleviating this problem is to replace quantum operations with classical processing. Despite the common practice of this approach, rigorous criteria to determine whether a given quantum operation is replaceable classically are still missing. In this work, we define the classically replaceable operations in four general scenarios. In each scenario, we provide their necessary and sufficient criteria and point out the corresponding classical processing. For a practically favorable case of unitary classically replaceable operations, we show that the replaced classical processing is deterministic. Beyond that, we regard the irreplaceability of quantum operations by classical processing as a quantum resource and relate it to the performance of a channel in a non-local game, as manifested in a robustness measure.
Programas nacionais de atividades físicas em Universidades Federais brasileiras e relações com o lazer
Authors: Silva Junior Vagner Pereira da
Published: October 2022

O estudo objetivou identificar políticas públicas federais de atividade física no contexto das universidades federais e analisar a relação com o lazer. Pautado no estudo histórico documental e na base bioecológica, evidenciou-se que as atividades físicas estiveram presentes nas universidades federais brasileiras por meio das práticas obrigatórias de Educação Física no ensino superior e programas/projetos (ProExt e Programa Segundo Tempo Universitário), estando apenas os programas/projetos vinculados às atividades físicas de lazer. Todavia, estes se mostraram incipientes e de baixo alcance, pouco contribuindo com competências favoráveis à incorporação desse tipo específico de atividade no ensino superior, a justiça social e desenvolvimento humano, com exceção do Programa Segundo Tempo Universitário, que demonstrou elementos favoráveis ao desenvolvimento humano. Conclui-se pela urgência de mudanças macrossistêmicas, por meio de política redistributiva que permita atendimento de todas as instituições federais de ensino superior, contemplando maior quantidade de discentes.
Identidade profissional e formação inicial em Educação Física Bacharelado
Authors: Anversa Ana Luíza Barbosa , Flores Patric Paludett , Silva Júnior Arestides Pereira da , Souza Vânia de Fátima Matias de , Farias Gelcemar Oliveira , Oliveira Amauri Aparecido Bássoli de
Published: October 2022

O estudo objetivou analisar como os estudantes-estagiários compreendem a constituição da identidade profissional na formação inicial em Educação Física bacharelado. Participaram da pesquisa qualitativa do tipo descritiva 30 estudantes-estagiários na realização de grupos focais. Os dados coletados foram analisados de forma descritiva a partir do procedimento técnico da análise de conteúdo e com o auxílio do software de análise qualitativa Nvivo10. Os resultados apresentados destacam que os estudantes-estagiários reconhecem que a abrangência da área amplia as possibilidades de intervenção; visualizam o mercado de trabalho altamente competitivo; percebem a área com pouco reconhecimento e baixa remuneração; indicam que a formação inicial do futuro profissional da área deve possibilitar a interação entre a teoria e a prática; e enfatizam a necessidade de um trabalho qualificado junto à sociedade para estimular o reconhecimento da área e do profissional de Educação Física.