bluuebunny/crossref_metadata_2025 huggingface dataset:
Increasing the Productivity of Rice (Oryza sativa) Crop via Exposure of a Micro Chip Audio Generator System
Authors: Suryadarma I Gusti Putu , Kadarisman Nur , Sugiharto Agus , Pramono Joko , Sari Emi Kurnia , Brams Dwandaru Wipsar Sunu
Published: September 2024

A technology revolution is needed to overcome the problem of food self-sufficiency in agriculture, i.e. a smart chip audio organic growth system (SC-AOGS). The objective here is to design, produce, and apply the SC-AOGS to rice (Oryza sativa) crops. The SC-AOGS exposes audio sound of local insects to the crops and triggers the opening of stomata so that the plants are able to absorb sunlight. The results show that better yields of crops under SC-AOGS exposure are obtained, the best yields are obtained at 4000 Hz, and the location of the beds does not affect the yields.
Security Certificates Used in Public Web Sites of Banks in Czech Republic, Slovakia and Hungary
Authors: Petrov Pavel , Malkawi Rami , Shichkin Andrey , Dimitrov Georgi , Nacheva Radka
Published: September 2024

There is a tendency formed during the last years – indicating that the default protocol for accessing web pages is the HTTPS protocol. In order this to be done, a valid SSL/TSL certificate issued by authority body should be used. In the scope of this study during the month of August 2019 we examined the web sites of 22 banks licensed in Czech Republic, 15 banks licensed in Slovakia and 22 banks licensed in Hungary. The survey excludes the foreign bank branches which are not supervised by the respective national central banks. We did this survey trying to outline the "good practices" which are used by domestic system administrators of bank's websites in the respective countries.
Shortening of Life Cycle and Complexity Impact on the Automotive Industry
Authors: Sabadka Dušan , Molnár Vieroslav , Fedorko Gabriel
Published: September 2024

The article is focused on vehicles life cycle and specific phenomena accompanying it. We aimed to review and define factors taken into account in the process of a vehicle development thus we have summarized methodically acquired knowledge of life cycle and complexity of vehicles, analyzed factors that are subject to world automobile production growth and the number of vehicle models selected by well-known manufacturers as well as vehicle generation at the time.
Knowledge Levels and Attitudes Toward Cybercrimes of Adolescents in Northern Cyprus
Authors: Ozdamli Fezile , Ercag Erinc
Published: September 2024

Besides the many positive effects of the use of information technologies, it also generates many problems. It is especially of great importance to determine the level of knowledge and awareness of individuals on the cybercrime. No studies have been conducted on this issue in the Turkish Republic of Northern Cyprus. Based on this, it was necessary to determine the knowledge level of adolescents who are frequent users of digital technologies regarding the cybercrimes and their attitudes toward them. This study is a descriptive survey model. The working group is composed of 407 adolescents in the TRNC. The data collection tool was “Concepts of Informatics and Student Opinion Survey on Cyber Crimes” developed by Gozler and Tasci (2015). The 5 point Likert scale questionnaire consists of 16 items. Frequency, percentage and mean analysis was applied during the data analysis. It is clear that cybercrime awareness in Northern Cyprus has to be increased.
Stimulating Innovation Activity in Enterprises within the Metallurgical Sector: the Russian and International Experience
Authors: Nikolaevich Dudin Mihail , Vasilievich Bezbakh Vitaliy , Vladimirovna Galkina Marina , Petrovna Rusakova Ekaterina , Borisovich Zinkovsky Sergey
Published: September 2024

This paper examines some of the Russian and international experience with regard to stimulating innovation activity in enterprises within the metallurgical sector. The key focus is on implementation issues regarding innovations within the sector and possible ways to resolve them. The authors explore the current state of innovation activity in metallurgical enterprises and examine some of the most promising areas for innovation in metallurgy. The paper brings forward a set of measures designed to enhance the stimulation of innovation activity in Russian metallurgical enterprises based on the experience of other European countries. The authors examine some of the most promising tenets of a government program on innovation-driven development within Russia’s metallurgical sector, which includes various measures of direct and indirect stimulation of innovation within metallurgy.
Exploring Student’s Productive Thinking in Solving Algebra Problem
Authors: Murtianto Yanuar Hery , Muhtarom Muhtarom , Nizaruddin Nizaruddin , Suryaningsih Septin
Published: September 2024

The purpose of this research is to describe student productive thinking in solving problem in algebra. The subject of this research is choosing four subjects which have different productive thinking. The first instrument is using self-regulated learning questionnaire, then the second instrument is giving a test and interviews. The result indicated that student with high self-regulated learning, thinks really critically, and his creativity has the ability of thinking productive. Students which have the ability to think productively have the following characteristics: they are able to identify problem well, they are able to write facts clearly and they are able to describe what is already known and what has been questioned in the question precisely, right in writing the mathematics model, and they are also able to make calculation and check the rightness which happen as well. They give more than one relevant idea and find more various ways dealing with the problems, give the answer in detail, clear and complex, make right conclusion and doing calculation precisely, double check their answers by using the known matter in the problem.
The Impact of E- Learning in Developing Academic Skills and Social Interaction among Students with Learning Disabilities in Jordan from the Perspective of their Teachers
Authors: H. Ziadat Ayed
Published: September 2024

The aim of this study is to identify the impact of e-Learning on the development of academic and social interaction skills among students with learning disabilities in Jordan from the perspective of their teachers. The study sample consisted of teachers of disabled students in Amman, Jordan, using the descriptive approach. The results showed that social interaction was on high level, and the academic skills were on the medium level among the second and the third grades from the teacher’s perspective. Also, the result showed that there are statistically significant differences in the social interaction according to the grade and the variance was in favor of the third grade.
Predictive Apriori Algorithm in Youth Suicide Prevention by Screening Depressive Symptoms from Patient Health Questionnaire-9
Authors: Sirisathitkul Yaowarat , Thanathamathee Putthiporn , Aekwarangkoon Saifon
Published: September 2024

This study employed the Predictive A priori algorithm in identifying significant questions of Patient Health Questionnaire-9 (PHQ-9) for suicide tendency prediction by using PHQ-9 and suicidal screening form (8Q). The random forest was applied to calculate the classification accuracy of PHQ-9 and 3 feature selection algorithms were applied to determine the attribute importance. The Predictive Apriori algorithm was applied to find the meaningful association rules. The classification accuracy of PHQ-9 is 92.12% and item no. 1 and no. 9 of PHQ-9 are less important. The significant risk factors associated with suicidal ideation are Item no. 2, no. 4, and no. 5.
Influence of Graduation Quality and Flight Training as a Vocational School on International Standard Job Opportunities
Authors: Iswahyudi Prasetyo , Tri Wijayati Dewie , Soedjarwo Soedjarwo , Hartono Sugi
Published: September 2024

This article aims to analyze the influence of graduate quality and flight training on international standardized job opportunities in Civil Aviation Safety and Engineering Academy of Surabaya. This explanatory research with a quantitative approach involves 75 graduates at Civil Aviation Safety and Engineering Academy of Surabaya. Data collection in this study was collected through a questionnaire. The data analysis technique we used was SEM analysis with the PLS program. This result indicates that graduates quality and flight training as vocational training have a significant and positive impact on international standard job opportunities in Civil Aviation Safety and Engineering Academy of Surabaya.
Research into Motivational Factors of Work Done by University Teachers from the Perspective of the Theory of Generations
Authors: V. Arkhipov Sergey , Vanchikova E. N. , Zolotareva N. A. , Yantranov A. E. , Budaeva D. T.
Published: September 2024

The article is devoted to the study of the main motivational factors that determine the teacher’s work from the position of the Strauss-Howe generational theory. In the course of the research, the experience of organizing the activities of a teacher of a university in the Republic of Buryatia, the authors identified imbalances in the structure of employment towards extracurricular activities, which significantly reduces the efficiency of the teacher’s work and their motivation for teaching. The current situation is fraught with negative consequences, and the administration of the universities must constantly adapt and apply latest educational technologies together with the system of teacher’s work stimulation, both material and non-material.
Future Physical Education Teachers’ Preparation to Use the Innovative Types of Motor Activity: Ukrainian Experience
Authors: Balashov Dmytro , Bermudes Diana , Rybalko Petrо , Shukatka Oksana , Kozeruk Yuliia , Kolyshkina Alla
Published: September 2024

The purpose of the paper is to substantiate the model of future physical education teacher’ preparation to use the innovative types of motor activity in professional activity. 267 respondents (204 students, future physical education teachers, and 63 teachers) participated in the research. Students were divided into two groups. The experimental group trained according to the author's model: future physical education teachers’ preparation to use the innovative types of motor activity in the professional activity. The indicators «Volume of knowledge», "Gymnastic preparedness" and "Organizational actions", "Self-analysis" were defined to examine the readiness of future physical education teachers to use the innovative types of motor activity in professional activity. Qualitative and quantitative changes for each indicators of the readiness of the future physical education teachers to use the innovative types of motor activity in professional activities are reflected in positive dynamics, which is confirmed at the significance level of 0.05 according to the Student's statistical test. The pedagogical experiment has shown the effectiveness of the author's model of future physical education teachers’ preparation to use the innovative types of motor activity in professional activities.
Synchronization and chaos in population dynamics models
Authors:   Saratov State University, Postnov Dmitrij , Balanov Aleksandr ,   Loughborough University, Cherniakov Vladislav ,   Saratov State University
Published: September 2024

We consider а microbiological system consisting of several bacteria—virus populations which are coupled via the flow of resources. The behavior of both continious time mathematical models and discrete time ones is discussed. The origin of complex behavior due to properties of coupling between the oscillators with regular dynamics is illustrated. While studying the one-dimentional array of discrete time population models we reveal the mechanism of rise of spatial inhomogeneity of stationary oscillatory regimes characteristics.
Synchronization in chaotic systems with denumerable set of equilibrium states
Authors:   Saratov State University, Postnov Dmitrij , Balanov Aleksandr ,   Loughborough University
Published: September 2024

Coupled chaotic systems, in each of which the set of a few characteristic time describes the complex oscillatory regimes, arc investigated. Variation of parameters changes these characteristic times and allows us under certain conditions to observe the processes which can be interpreted in terms of synchronization phenomenon. It is shown, that the «locking» mechanism can be extended both to the mean resident time of system’s state near the one of the equilibrium points and to the time which corresponds to the mean drift rate of system’s state.
Hacia una conceptualización holística de la gestión del conocimiento en los Sistemas Nacionales de Innovación
Authors: López De la O Mónica Vanessa
Published: September 2024

Como parte de un programa doctoral en Estudios Humanísticos en Ciencia, Tecnología y Sociedad, se presenta el enfoque metodológico y los avances de la investigación que buscan conceptualizar a los Sistemas Nacionales de Innovación (sni) como fundamento de la gestión nacional del conocimiento con base en el caso mexicano, lo que incluye una aproximación comparativa con los casos sudamericano y nórdico.
Se trata de responder a la pregunta central: ¿cómo viven las personas investigadoras y cómo manifiestan sus instituciones las dimensiones social, cultural e institucional dentro del sistema nacional de innovación de México? El objetivo general es identificar, relacionar e integrar tales dimensiones como parte del funcionamiento del sni mexicano, en términos de una sólida articulación para la generación, la diseminación y el uso del conocimiento en el país.
Specifics of the Legal Mechanism of Export Control of Dual-Use Goods
Authors:   Research Scientist of the State Archive of Sverdlovsk Region, PhD (Political Science), Verbitskaya Tatyana V.
Published: September 2024

The work is devoted to the study of the specifics of law mechanism of export control in terms of determining the ways of its further development. It has been established that due to the ever-increasing intensification of the dual-use goods circulation, it is necessary to improve constantly the mechanism for export control of such goods in order to prevent and suppress cross-border offenses in this area. It has been determined that the multiple movement of goods, including crossing borders of countries in crisis of political and legal systems, creates an opportunity to hide certain functions of goods, such as the possibility of hitting objects and people and committing other similar offenses. The authors come to the conclusion that it is necessary to develop regional and universal international mechanisms based on an interstate agreement on the export control of dual-use goods, an element of which will be the information exchange of customs authorities regarding the export of dual-use goods.
Unmanned Air Transportation: Problems and Peculiarities of Legal Regulation
Authors:   Associate Professor of the Department of Civil Law of the Saratov State Law Academy, PhD (Law), Boyarskaya Yulia N.
Published: September 2024

One of the most important and priority areas of state policy is the development of the transport system. This is especially true in the context of digital transformation. On the territory of the Russian Federation, unmanned aerial vehicles are being developed and successfully operated under the conditions of an experimental legal regime. However, at present there is no detailed legal regulation of relations in the field of unmanned air transportation of passengers and cargo, which, in turn, hinders the development of such transportation in the country.
Problems of State and Legal Protection of Self-Employed in Russia
Authors:   Professor of the Department of Theory of Law and State and Legal Disciplines of the International Law Institute, Glotov Sergey A. , Kurkina Natalya V. ,   Associate Professor of the Department of General Jurisprudence of the Faculty of Jurisprudence and Legal Regulation of the Russian State Social University
Published: September 2024

The article provides a comparative legal analysis of the experience of practical implementation of the institute of self-employed citizens in Russia, evaluates the positive and negative experience of using this legal institution. The authors consider the trends in the development of self-employment, analyze the dynamics of the growth of the number of self-employed citizens in Russia and, based on this, make proposals on the effectiveness of the special tax regime.
Legal Issues of Blocking of Cash and Property as a Special Economic Measure
Authors:   Professor of the Department of Financial Law of the Russian State University of Justice, Proshunin Maksim M.
Published: September 2024

This article examines the legal issues of blocking (freezing) funds and other property within the framework of Russian anti-sanctions legislation. In the article, the author examines applied legal issues related to the definition of the content of the term "person controlled by a blocked person", points out the imperfection of the mechanism for determining controlled persons and suggests supplementing the analysis of each draft law containing indications of the need to verify legal entities and individuals against various lists with IT expertise. Among the legal gaps, the author also highlights the lack of norms governing the unblocking of assets of the blocked person. In conclusion, the author considers it advisable to establish a grace period for non-application of measures of influence and administrative responsibility for violation of anti-sanctions legislation.
The Correlation between Maturity, Plant Architecture and Yield Related Traits of Soybean Cultivars in Northern China
Authors: Zhu Xiaobin , Wu Shihao , Wu Hongyan , Zhang Wenjing , Xia Zhengjun
Published: September 2024

Background: The traits of the time to flowering and maturity and other important agronomic traits, e.g., plant height, the numbers of nodes and branches are key factors for the adaptability of soybean cultivars to a certain photoperiodic length and ecological environment. Correlation analysis of these traits will facilitate fine-tuning of phenotyping procedure for each trait. Methods: In this field investigation during 2017-2020 at two experimental stations in Heilongjiang Province, northern China, a total of 1133 cultivars or accessions were phenotyped for traits related to maturity, architecture, e.g. plant height, the numbers of nodes and branches and yield. Statistical analysis was performed to reveal the correlation between different traits, years and locations. Result: R1 (days to the first flowering stage) and R2 (days to the fully flowering stage) are strongly stable traits among different years and different locations in this study. Significant correlations were identified between maturity trait, plant height, the numbers of nodes and branches. However, the traits of the height of the first effective node and the pod number per plant demonstrated some weak correlation among different years or with these maturity traits. Therefore, phenotyping procedures in this study can be directly applicable for accurate evaluation of maturity and plant architecture-related traits e.g. plant height, the numbers of nodes and branches.
Os impactos socioambientais na região da Serra do Piriá, Viseu-PA sob o enfoque da geoecologia das paisagens
Authors: Pereira de Souza Wellington , Vidal Maria Rita
Published: September 2024

O objetivo é analisar os impactos socioambientais em seis comunidades do entorno da Serra do Piriá, no Nordeste do Pará. As paisagens foram diretamente afetadas pelas atividades humanas (mineração, pecuária, extrativismo) e suas consequências relacionadas à apropriação dos recursos naturais. A metodologia baseia-se nos pressupostos da análise ambiental com vistas à Geoecologia das Paisagens para analisar os impactos socioambientais que, em conjunto com autores renomados, servirão de arcabouço para a compreensão dos fenômenos socioambientais, fazendo uso das delimitações das unidades e análise temporal. Entre os principais resultados está a delimitação de sete Unidades Geoecológicas (UG), que associadas ao uso do solo demonstram degradação. As atividades humanas podem provocar alterações irreversíveis nas paisagens em questão, necessitando de ações de conservação e preservação.
Perceptions of school administrators, teachers, and students on the use of CCTV cameras and their impact on learning mathematics
Authors: Kunwar Rajendra
Published: September 2024

The use of CCTV cameras has been increasing in educational settings due to their potential benefits in enhancing security, monitoring student behavior, and promoting a conducive learning environment. This study aims to explore the perceptions of administrators, teachers, and students regarding the use of CCTV cameras in schools and their impact on learning mathematics. The study adopts a mixed-method approach, incorporating semi-structured interviews and observations to examine the presence of CCTV cameras and their influence on classroom dynamics and behaviors in teaching and learning mathematics. Semi-structured interviews were conducted with school administrators, teachers, and students from six schools in Nepal. The analysis of the data revealed five main themes: individual privacy, autonomy and trust, school context and learning environment, discipline and safety measures, and school management system, along with limitations and constraints. These themes encompassed discussions on the potential benefits of CCTV cameras in promoting discipline, safety, and classroom management, as well as concerns related to privacy, autonomy, trust, student motivation, engagement, critical thinking skills, and classroom dynamics. The findings provide valuable insights for policymakers, school administrators, and educators to make informed decisions and develop appropriate guidelines for the responsible integration of CCTV cameras in educational settings.
Keywords: Administrators; CCTV cameras; learning environment; mathematics; monitoring; perceptions; students; teachers.
Humanitarian Evidence and Discourse Summary August 2024
Authors: Kelly Luke
Published: September 2024

Monthly Humanitarian Evidence and Discourse Summaries aim to signpost FCDO and others to the latest relevant evidence and discourse on humanitarian action. It is structured around FCDO humanitarian framework themes: Protect: Protect civilians, IDPs, refugees, marginalised groups including women and girls, and humanitarian access. Prioritise: Prioritise effective humanitarian assistance to people in greatest need. Prevent: Prevent and anticipate future shocks and rebuild resilience in protracted and recurring crises. Further detail on methodology and scope at the end. Click on the hyperlinks to bring you to the relevant literature. We hope this is a useful resource and you can read all the articles produced by brilliant authors and organisations(!), but each month we also invite a guest to identify their five “star reads” from the wider list. This does not represent an organisational position or assessment of rigour, but rather a personal choice of published evidence, guidance or discourse that are of special interest or impact. This month, Jess Camburn, CEO of ELHRA, highlights her five star reads.
Efeito do monitoramento telefônico de Intervenções Breves para uso de álcool entre gestantes: ensaio clínico randomizado
Authors:   Escola de Enfermagem de Ribeirão Preto, Moura Adaene Alves Machado de , Pillon Sandra Cristina ,   Escola de Enfermagem de Ribeirão Preto, Júnior Fernando José Guedes da Silva ,   Universidade Federal do Piauí, Zerbetto Sônia Regina ,   Universidade Federal de São Carlos, Pegoraro Natália Priolli Jora ,   Escola de Enfermagem de Ribeirão Preto, Cruz Jefferson Pereira Maciel da ,   Universidade Federal de São Carlos, Aliane Poliana Patrício ,   Universidade de São Paulo, Gonçalves Angélica Martins de Souza ,   Universidade Federal de São Carlos
Published: September 2024

bjetivo: testar se o monitoramento por telefone acrescenta efeito à aplicação de Intervenções Breves para o uso de álcool entre gestantes. Metodologia: trata-se de ensaio clínico controlado e randomizado, aberto, paralelo, com dois braços. Os dados foram coletados na atenção primária à saúde de São Carlos e Centro de Referência de Saúde da Mulher em Ibaté (São Paulo, Brasil). Foram rastreadas gestantes que consumiram qualquer quantidade de álcool na gestação. Após, foram alocadas aleatoriamente em dois grupos. O grupo controle recebeu apenas uma intervenção breve; o grupo experimental recebeu uma intervenção breve e foi monitorado semanalmente por telefone nas duas semanas posteriores à intervenção. Utilizou-se programa estatístico para realização de estatísticas descritivas e inferencial (Teste de Wilcoxon). Resultados: Houve redução do consumo nos dois grupos. Porém, apenas no grupo experimental em que foi implementado intervenção com monitoramento, houve abstinência de todo o grupo (AUDIT-C: p-valor=0,011; T-ACE: p-valor=0,010). Conclusões: Intervenções breves associadas a monitoramento telefônico durante a gestação se mostraram efetivas para a cessação do consumo de álcool. O monitoramento contínuo após intervenções breves melhora as taxas de abstinência de álcool. Registro Brasileiro de Ensaios Clínicos: RBR-4y4k7w.
Traverses en bois pour le chemin de fer transcamerounais. Problèmes de préservation des bois au contact du sol dans les pays tropicaux. 1re partie
Authors: Fougerousse M.
Published: September 2024

Le projet de chemin de fer Transcameroun a été l'occasion d'examiner la possibilité d'utiliser des traverses en bois local. Un groupe d'experts a dressé une liste des essences technologiquement adaptées dans les régions du Cameroun où le bois est déjà cultivé et a défini une méthode de préservation permettant d'assurer une durée de vie satisfaisante. La deuxième partie de cet article traite des différents types de produits de préservation du bois qui peuvent être utilisés pour préserver le bois en contact avec le sol dans les pays tropicaux.L'auteur analyse ensuite les résultats d'un certain nombre d'expériences effectuées sur le terrain, visant à juger de la durabilité relative de ces différents produits, et conclut par une comparaison des solutions pratiques qui peuvent être préconisées pour la conservation durable, en climat tropical, des bois utilisés pour les traverses de chemin de fer, les ponts, les poteaux, etc...
Uma análise das recomendações de tipos e usos de dicionários escolares do Plano Nacional do Livro Didático
Authors: Pereira Anderson de Carvalho
Published: September 2024

Este artigo considera o dicionário como um instrumento do processo de gramatização descrito por Auroux e como uma das manifestações da língua imaginária, tal como conceituada em Orlandi. Ao partir destes pressupostos, apresenta uma análise discursiva das concepções de língua e de ensino propostas pelo Plano Nacional do Livro Didático, especificamente em suas diretrizes para tipos e usos de dicionários escolares. Para isto, interpreta um corpus formado por recortes do manual “Com direito à palavra: dicionários em sala de aula”, guiando a análise pela divisão feita pelo documento entre os tipos de dicionários de uso escolar e recomendações de atividades. Conclui que alguns conceitos de língua ali elencados, bem como processos discursivos envolvidos nestas recomendações de usos, recortam sentidos em disputa no campo da Educação.
The Influence of the Tanah Lot Art and Food Festival on Tourist’ Visiting Interest
Authors: Ni Kadek Ni Kadek Intan Permata Putri , I Nengah Wirata  , Nyoman Reni Ariasri
Published: September 2024

Purpose: This research aims to determine the influence of the Tanah Lot Art and Food Festival on tourists' interest in visiting Tanah Lot.
Method: This research employs a quantitative approach at the Tanah Lot Tourist Attraction (DTW) in Beraban, Tabanan, over a five-month period (January - May 2024). Data was collected through questionnaires to examine the influence of the Tanah Lot Art and Food Festival on tourists' interest in visiting. Data analysis was conducted using simple linear regression with SPSS.
Result: The results indicate that the Tanah Lot Art and Food Festival has a positive and significant impact on tourists' interest in visiting, both partially and simultaneously. Partially, the t-value (5.398) exceeds the t-table value (1.660), and the significance value (0.000) is less than 0.05. Simultaneously, the F-value (12.875) exceeds the F-table value (2.70), and the significance value (0.000) is less than 0.05. The festival contributes 35.2% to the tourists' interest in visiting, while 64.8% is influenced by other variables not examined in the study.
Contribution: This research makes significant contributions in several areas. Theoretically, it enhances the literature on the impact of art and food festivals on tourist interest. Practically, the findings offer valuable insights to the management of Tanah Lot Tourist Attraction (DTW) and local government on strategies to boost tourist visits through event organization. Additionally, from a policy perspective, the empirical evidence provided can support the formulation of policies for the development and promotion of event-based tourism
Técnicas educativas na assistência pré-natal humanizada
Authors: Moraes Mariana Souza , Moreira Samantha Ferreira da Costa
Published: September 2024

Introdução: O presente estudo foi realizado no intuito de difundir ferramentas socioeducativas que humanizem o parto e deem assistência de forma eficaz e educativa ao pré-natal de gestantes. Além disso, como ferramenta, foram apuradas as dúvidas, medos e anseios mais comuns que ocorrem no meio gestacional, sendo as pautas estudadas foram baseadas nesse contexto. Objetivo: análise dos dados para proporcionar ferramentas educativas para gestantes e puérperas de modo social e humanizado. Materiais e Métodos: O estudo foi conduzido de forma exploratória e qualitativa e foi desenvolvido com 13 gestantes no município de Mineiros – Goiás (GO), que participaram de forma ativa virtualmente. Foi aplicado um questionário para coleta de dados pessoais e foram enviados periodicamente às participantes vídeos explicativos de temas obstétricos diversificados, além de reuniões online voltadas para o debate e relatos de experiências entre gestantes e profissionais da saúde. Resultados: Foram colhidos resultados satisfatórios de que as técnicas educativas difundidas foram proveitosas e de suma importância na gestação, parto e puerpério das gestantes. Conclusão: Demonstra-se que são necessárias mais medidas educativas voltadas para esse âmbito, pois ainda há lacunas a serem preenchidas, como maior acesso à informação e mais apoio psicossocial para garantir que as gestantes vivenciem a maternidade de forma saudável, segura e com autonomia, para um melhor bem-estar da mãe e do bebê.
Role of probiotic extracellular vesicles in inter-kingdom communication and current technical limitations in advancing their therapeutic utility
Authors: Sanwlani Rahul , Bramich Kyle , Mathivanan Suresh
Published: September 2024

Diverse functions of probiotic extracellular vesicles (EVs) have been extensively studied over the past decade, proposing their role in inter-kingdom communication. Studies have explored their therapeutic role in pathophysiological processes ranging from cancer, immunoregulation, and ulcerative colitis to stress-induced depression. These studies have highlighted the significant and novel potential of probiotic EVs for therapeutic applications, offering immense promise in addressing several unmet clinical needs. Additionally, probiotic EVs are being explored as vehicles for targeted delivery approaches. However, the realization of clinical utility of probiotic EVs is hindered by several knowledge gaps, pitfalls, limitations, and challenges, which impede their wider acceptance by the scientific community. Among these, limited knowledge of EV biogenesis, markers and regulators in bacteria, variations in cargo due to culture conditions or EV isolation method, and lack of proper understanding of gut uptake and demonstration of in vivo effect are some important issues. This review aims to summarize the diverse roles of probiotic EVs in health and disease conditions. More importantly, it discusses the significant knowledge gaps and limitations that stand in the way of the therapeutic utility of probiotic EVs. Furthermore, the importance of addressing these gaps and limitations with technical advances such as rigorous omics has been discussed.
In-situ transmission electron microscopy shedding light on the mechanical properties of nanoscale materials
Authors: Liu Chunmeng , Yang Kemeng , Zhang Jiaqi , Cheng Shaobo , Shan Chongxin
Published: September 2024

Characterizing the mechanical properties of nanomaterials (NMs) has always been a challenge for researchers due to their size effect and the difficulty of sample manipulation. In recent years, researchers have integrated scanning tunneling microscopy, atomic force microscopy and other techniques into transmission electron microscopy (TEM); thereby, advanced in-situ TEM nanomechanical measurement techniques for NMs have emerged. The study of mechanical properties using in-situ TEM allows a direct correlation among mechanical properties, atomic structures, and their dynamic processes. However, systematic reviews on these in-situ TEM measurement techniques, their working principles, and the corresponding results obtained by these methods are still limited. This review introduces the basic principles of recently developed in-situ TEM techniques (including TEM-atomic force microscopy and TEM-microelectromechanical systems), the features of these measurement techniques, the research progress in characterizing the mechanical properties and deformation behaviors of NMs by the in-situ TEM, and the influence of surface effects and defects on the mechanical properties of NMs. In perspective, several challenges regarding improving the in-situ TEM technique and analyzing the in-situ TEM data are addressed.
History of breeding programmes for fungus resistant grape varieties in Europe, France and the Occitanie region
Authors: Paire Caroline , Dolet Marc-Antoine , Hannin Hervé , Samsom Alain , Olivier Valérie , Chervin Christian , Geffroy Oliver , Cheriet Foued
Published: September 2024

Fungus tolerant grape varieties (RVs) are emerging as a promising solution in a viticultural context characterised by growing societal, environmental, and regulatory tensions. Since the 1930s, several countries have launched research programmes that aim at developing disease-resistant hybrids. Today, 66 resistant grape varieties are registered in at least one of the European catalogues. The historical overview and dynamic integration of RV have not been the subject of a large number of scientific articles. This makes it necessary to explore grey literature such as Vitisphère (www.vitisphere.com), a French daily online magazine created in 2000 specialised in wine industry. Through a press review, this article provides historical background to European breeding programmes and an overview of their perception in France and Occitanie, gathering over 543 articles on the topic of RVs published between 2009 and end June 2024.
Gestion de la reproduction sans hormones chez les mammifères d’élevage en AB en France
Authors: PELLICER-RUBIO Maria-Teresa , FRÉRET Sandrine , FERCHAUD Stéphane , BOULOT Sylviane , BIDAN Fabrice , DE CRÉMOUX Renée , BARTHÉLÉMY Diane , ROUZEYROL Léa , EXPERTON Catherine , GOUDET Ghylène
Published: September 2024

Le cahier des charges en agriculture biologique (AB) interdit les traitements à base d’hormones ou substances analogues en vue de maîtriser la reproduction. En AB, la reproduction des petits ruminants est possible à contre-saison grâce à l’effet mâle. Les traitements lumineux sans mélatonine pour désaisonner la reproduction peuvent aussi être appliqués en bâtiments ouverts et sont compatibles avec le pâturage mais peu utilisés sur le terrain. L’insémination animale (IA) est peu répandue pour les ovins et caprins en AB, elle peut être réalisée sur chaleurs naturelles (saison sexuelle) ou induites et synchronisées par effet mâle (contre-saison). Dans les deux cas, les IA s’étalent sur plusieurs jours et nécessitent une détection des chaleurs préalable. En élevages caprins, la conduite en lactation longue est également une alternative pour désaisonner la production laitière. Dans les élevages porcins en AB, l’effet mâle peut faciliter l’induction de la puberté des cochettes, la stimulation d’œstrus de lactation, et la diminution de l’intervalle sevrage-œstrus ; toutefois il est utilisé principalement pour améliorer l’expression des chaleurs. La stimulation par le transport et le changement social et/ou d’environnement est largement utilisée pour induire et synchroniser les œstrus des cochettes de renouvellement. Chez les bovins, l’interdiction des traitements hormonaux n’est pas pénalisante en AB, car la reproduction est possible toute l’année par monte naturelle (majoritaire en élevage allaitant) ou par IA (majoritaire en élevage laitier) sur chaleurs naturelles. Dans toutes les espèces, le « flushing » alimentaire avant la mise à la reproduction est pratiqué dans le but d’améliorer la fertilité. La mise en œuvre de ces pratiques en AB est le résultat d’un équilibre entre enjeux financier, réglementaire et éthique.
Produire et mettre en marché des produits animaux issus de l’agriculture biologique : un moteur pour la transition vers l’agroécologie ?
Authors: NOZIÈRES-PETIT Marie-Odile , CHIFFOLEAU Yuna , VEYSSET Patrick
Published: September 2024

L’agriculture biologique (AB) est un mode de production, certifié par un tiers et associé à une segmentation des marchés des produits d’élevage sous signe officiel de qualité. Avec une montée en puissance dans la fin du XXe siècle, cette démarche, structurée avant tout par l’interdiction des intrants de synthèse, est vue comme un outil majeur de la transition agroécologique des élevages. Cet article vise à interroger cette position. Il présente tout d’abord en quoi le cahier des charges de l’AB contribue, par certains côtés, à la transition agroécologique. À travers le cas de la viande bovine, il montre aussi comment le marché pèse sur les systèmes de production et freine cette transition en n’évitant pas l’agrandissement des élevages et l’adoption de pratiques visant à améliorer la productivité des animaux. Il s’appuie ensuite sur deux situations que sont i) la production de lait de brebis dans les Causses du Sud, en partie destinée à l’AOP Roquefort, et ii) les viandes bovines et ovines de l’Est pyrénéen pour interroger la nécessité d’avoir des outils de gouvernance territoriale opérants, qui peuvent s’appuyer, le cas échéant sur ceux de démarches existantes, de type indication géographique. Il invite ainsi à la réflexion sur la reterritorialisation de tout ou partie des filières en AB.
Avant-propos au numéro spécial « L’élevage biologique : conditions et potentiel de développement »
Authors: MÉDALE Françoise , BAREILLE Nathalie , PENVERN Servane
Published: September 2024

Après une synthèse des évolutions majeures qui se sont produites depuis 15 ans en termes de réglementation, de politiques publiques, de production, de consommation et de recherches dans le domaine de l'agriculture biologique (AB), cet avant-propos présente le sommaire de ce numéro spécial consacré à l'élevage biologique. Les articles issus, en majorité, de travaux conduits par INRAE et ses collaborateurs dans le cadre de programmes dédiés à l’AB, analysent les conditions et le potentiel de développement de l’élevage bio avec des regards techniques, économiques et organisationnels.
La nouvelle réglementation de l’élevage bio
Authors: MÉDALE Françoise , PENVERN Servane
Published: September 2024

Cet article synthétise les principales règles à respecter par les élevages biologiques selon la nouvelle réglementation européenne relative à l’AB, entrée en vigueur depuis le 1er janvier 2022 dans l’ensemble des États membres. Par rapport au précédent, le nouveau Règlement concerne davantage d’espèces animales. Certaines des règles visant à appliquer les principes de naturalité, de lien au sol, et de garantie d’un haut niveau de bien-être animal sont plus détaillées et parfois plus strictes, avec une diminution des possibilités de dérogations. Après un résumé des conditions de certification de l’élevage AB, nous exposons les mesures réglementaires relatives à la provenance des animaux, au choix des races et souches et aux méthodes de reproduction autorisées ainsi que celles concernant l’alimentation des animaux, leurs conditions d’hébergement, la gestion de leur santé et de leur bien-être. Pour chaque thème, nous précisons les règles s’appliquant à toutes les espèces couvertes par la réglementation européenne (bovins, ovins, caprins, équins, porcins, volailles, abeilles, animaux d’aquaculture), ainsi que les principales particularités par espèce.
Clinical benefit and safety profile of cross-line therapy with CDK4/6 inhibitors: a retrospective study of HR+/HER2– advanced breast cancer
Authors: Zhao Qi , Jiang Mingxia , Liu Jiaxuan , Zhang Mengqi , He Maiyue , Zhou Shihan , Wang Jiani , Mo Hongnan , Lan Bo , Yuan Peng , Zhang Pin , Ma Fei , Li Qiao , Xu Binghe
Published: September 2024

Objective: CDK4/6 inhibitors (CDK4/6is) in combination with endocrine therapy have secured a central role in the treatment of hormone receptor (HR)-positive advanced breast cancer (ABC) and have transformed the therapeutic landscape. Cross-line CDK4/6i therapy in which another CDK4/6i is continued after progression on a prior CDK4/6i may still offer advantageous therapeutic effects. Cross-line CDK4/6i therapy is an area of active investigation in the ongoing pursuit to improve outcomes for patients with HR+/human epidermal growth factor receptor 2 (HER2)– ABC. Methods: This retrospective study enrolled 82 patients with HR+/HER2– ABC who were treated with cross-line CDK4/6is (abemaciclib, palbociclib, ribociclib, and dalpiciclib) after progression with another CDK4/6i. The primary endpoint was progression-free survival (PFS) according to version 1.1 of the Response Evaluation Criteria in Solid Tumors. Secondary endpoints included toxicity, objective response rate, disease control rate, and overall survival. Adverse events (AEs) were graded according to version 5.0 of the Common Terminology Criteria for Adverse Events, as promulgated by the U.S. Department of Health and Human Services. Results: Eighty-two HR+/HER2– ABC patients who received cross-line CDK4/6i therapy from January 2022 to February 2024 were enrolled. The median age of the patients was 60 years. The median PFS of all patients was 7.6 months (95% CI, 5.9-9.2). Cox regression analysis identified lung metastasis and a switch to endocrine therapy following prior CDK4/6i therapy as independent predictive factors for PFS. Notably, patients who previously received abemaciclib and switched to palbociclib upon disease progression had a median PFS of 10.7 months. The strategy of transitioning to chemotherapy after progression on a prior CDK4/6i, then to a subsequent CDK4/6i merits further investigation. Hematologic toxicity was the most common grade ≥ 3 AEs. No instances of fatal safety events were observed. Conclusion: Cross-line CDK4/6i therapy is associated with significant clinical benefits and manageable safety profiles in patients with HR+/HER2– ABC, which underscores cross-line CDK4/6i therapy potential as an effective treatment strategy.
The Impact of Restrictive Macroprudential Policies through Borrower-Targeted Instruments on Income Inequality: Evidence from a Bayesian Approach
Authors: Zungu Lindokuhle Talent , Greyling Lorraine
Published: September 2024

The study used the data from emerging markets to examine the impact of restrictive macroprudential policies on income inequality from 2000–2019 using Bayesian panel vector autoregression and Bayesian panel dynamics generalized method of moments models. The chosen models are suitable for addressing multiple entity dynamics, accommodating a wide range of variables, handling dense parameterization, and optimizing formativeness and heterogeneous individualspecific factors. The empirical analysis utilized various macroprudential policy proxies and income inequality measures. The results show that when the central banks tighten systems using macroprudential policy instruments to sticker debt-to-income and financial instruments for lower-income borrowers (the bottom 40% of the income distribution) promote income inequality in these countries while reducing income inequality for high-income borrowers (the high 1 per-cent of the income distribution). The impact loan-to-value ratios were found to be insignificant in these countries. Fiscal policy through government expenditure and economic development reduces income inequality, while money supply and oil price shocks exacerbate it. The study suggests implementing a progressive debt-to-income (DTI) ratio system in emerging markets to ad-dress income inequality among lower-income borrowers. This would adjust DTI thresholds based on income brackets, allowing lenient credit access for lower-income borrowers while stricter limits for higher-income borrowers. This would improve financial stability and reduce income disparities. Additionally, targeted financial literacy programs and a petroleum-linked basic income program could be implemented to distribute oil revenue to lower-income households. Monetary Supply Stabilization Fund could also be established to maintain financial stability and prevent excessive inflation.
Harmonizing Quantum Gravity with Thermodynamics: Determination of the EUP Parameter by Prigogine’s Law
Authors: Sonnino Giorgio
Published: September 2024

In 1974, Stephen Hawking made the groundbreaking discovery that black holes emit thermal radiation, characterized by a specific temperature now known as the Hawking temperature. While his original derivation is intricate, retrieving the exact expressions for black hole temperature and entropy in a simpler, more intuitive way without losing the core physical principles behind Hawking's assumptions is possible. This is obtained by employing the Heisenberg uncertainty principle which is known to be connected to the vacuum fluctuation. This exercise allows us to easily perform more complex calculations involving the effects of quantum gravity. This work aims to answer the following question: \textit{Is it possible to reconcile Prigogine's second law of thermodynamics for open systems and the second law of black hole dynamics with Hawking radiation}? Due to quantum gravity effects, the Heisenberg uncertainty principle has been extended to the Generalized Uncertainty Principle (GUP) and successively to the Extended Uncertainty Principle (EUP). The expression for the EUP parameter is obtained by conjecturing that Prigogine's second law of thermodynamics and the second law of black holes are not violated by Hawking thermal radiation mechanism. The modified expression for the entropy of a Schwarzschild black hole is also derived.
A Survey of the Routing Problem for Cooperated Trucks and Drones
Authors: Dang Shuo , Liu Yao , Luo Zhihao , Liu Zhong , Shi Jianmai
Published: September 2024

The emerging working mode of coordinated trucks and drones has demonstrated significant practical potential in various fields, including logistics and delivery, intelligence surveillance reconnaissance, area monitoring, and patrol. The seamless collaboration between trucks and drones is garnering widespread attention in academia and has emerged as a key technology for achieving efficient and secure transportation. This paper provides a comprehensive and in-depth review of the research status on the routing problem for coordinated trucks and drones, covering aspects such as application background, cooperative modes, configurations, issues have been taken into consideration, and solution methodologies.