bluuebunny/crossref_metadata_2025 huggingface dataset:
Immunossuppression in Neuromyelitis Optica Spectrum Disorder: A Trial Sequential Analysis and Updated Meta-Analysis v1
Authors: Menegaz de Almeida Artur , Eduarda Cavalcanti Maria , Cezar Aquino de Moraes Francisco , Westphal Filho Fernando , Barros Andrade Ítalo , Robeto Moss Lopes Paulo , Rocha Dantas Clara , Rachas Reis Mariana , Fernandes Lilianne , Alves Kelly Francinny
Published: June 2024

Neuromyelitis Optica Spectrum Disorder (NMOSD) is a devastating, disabling, autoimmune disease with a prevalence of up to 10 cases per 100,000 people. Although NMOSD pathophysiology is not yet fully understood, disruption of the blood-brain barrier (BBB) possibly initiates the disease course through AQP4-IgG passive transit into the CNS compartment, with subsequent absorption by perivascular astrocytes endfeet expressing. NMOSD treatment is based on treating and preventing attacks by administering both high-dose glucocorticoids and long-term immunosuppressive therapy. The most recommended first-line therapy for NMOSD is Rituximab, Azathioprine, and Mycophenolate mofetil. Once NMOSD treatment with RTX, AZA, and MMF effects still have to be explored, the purpose of our study is to fill the gap of previous studies by assessing RTX isolated effectiveness and its comparative safety and efficacy when compared to AZA and MMF for NMOSD patients in a more critical statistical analysis.
SynGO analysis v1
Authors: Chen Chuyu
Published: June 2024

synapse function and gene enrichment analysis
FFPE Blocking and Sectioning - UMN TMCs v1
Authors: Forster, HT(ASCP)QIHC Colleen
Published: June 2024

FFPE Blocking and Sectioning protocol from BLS Histology at the University of Minnesota.
Peculiarities of commissions of forensic medical examinations in criminal cases related to crimes against sexual inviolability
Authors: Fokina Ekaterina V. , Barinov Evgeny Kh. , Barinov Andrey E. , Fokin Alexey S. , Cherkalina Elena N.
Published: June 2024

The investigation of criminal cases related to sex crimes determines the range of circumstances to be immediately proved during investigations. Issues arising in the process of conducting such cases must be resolved as part of forensic medical examinations. Illegal acts of a sexual nature generally end in the violation of human health, not only physical with bodily harm but also psychological. During such examinations, specialists of various clinical specialties are included in the composition of expert commissions. These are specialists in the fields of obstetrics-gynecology, venereology, traumatology, psychiatry, and clinical psychology. During investigation and trial, important information can be provided by medical documents on the state of health of the victim, including the testimony of medical workers. Not only forensic medical experts who conducted examinations but also medical workers are called to court hearings as witnesses to incidents. This article analyzed the commissions of forensic medical examinations in a teenager harmed by violent sexual acts. The results of forensic medical examinations were analyzed. This article provides an expert observation of a victim of crimes against sexual inviolability that led to severe complications. During the investigation, the development of a mental disorder in the teenager was examined, and a forensic medical examination was performed. Psychological injuries are no less serious than physical ones. The body’s response to stress causes a pathological state of the psyche. Such a painful reaction can persist for many years. A prolonged depressive reaction due to an adaptation disorder arose in the victim after the unlawful actions committed against her with a direct causal relationship. When conducting forensic medical examinations related to illegal acts of a sexual nature, specialists in the fields of gynecology, traumatology, venereology, psychiatry, and clinical psychology must take part in the examinations.
Сharacterization of the immune microenvironment’s cellular composition and its influence on gene expression during metaplastic changes of the gastric mucosa epithelium
Authors: Slepov Iurii K. , Emelin Aleksey M. , Deev Roman V.
Published: June 2024

BACKGROUND: Intestinal metaplasia of the gastric mucosa epithelium in chronic atrophic gastritis is considered a precancerous condition; however, it is potentially reversible. The study of the regulation mechanisms of metaplastic epithelial changes may help in understanding carcinogenesis and cancer prevention.
AIM: To determine whether the microenvironment is related to the development of gastric mucosa epithelium metaplasia in patients with chronic atrophic gastritis by assessing gene expression and cellular composition of immune infiltrates.
MATERIALS AND METHODS: In this retrospective cohort study, the alternative hypothesis was that the composition of the immune microenvironment of the gastric mucosa differed between cases with and without metaplastic changes in the epithelium. Biopsy specimens of the mucosa (n=38) obtained during endoscopic examination from five stomach sites (2 from the antrum, 2 from the body, and 1 from the corner) in patients with chronic atrophic gastritis of unspecified etiology and results of RNA sequencing of biopsy specimens of patients with chronic gastritis registered in the NCBI open database (n=12) were analyzed. Histological analysis, histochemical staining methods, and immunohistochemical study and morphometric, statistical, and bioinformatic analyses were performed.
RESULTS: The proportion of macrophages, T-cytotoxic lymphocytes, and plasmocytes increased in the samples with metaplastic changes of the gastric mucosa epithelium. A correlation was found between T-cytotoxic lymphocytes and risk for metaplasia. It was found that changes in the number of B cells, macrophages M2, T-regulatory cells and NK-cells are associated with increase in the expression of six genes most specific for intestinal-type epithelium.
CONCLUSION: The significant difference in the composition of the immune microenvironment between samples with and without metaplastic changes in the mucosal epithelium indicates the potential influence of immune cells on the development of metaplasia and progression of the pathological process along the Correa cascade. One of the mechanisms of regulation of metaplasia development by the microenvironment may be their influence on gene expression as an epigenetic factor.
The Mediated Moderating Effect of Self-Esteem between Depression and Anxiety in Childhood, Feeling of Intimidation, and Suicidal Ideation
Authors:   Research Institute For Life And Culture Sogang University, Paek Seung A
Published: June 2024

This study compared and analyzed the mediating effect of depression and the moderating effect of self-esteem on the effects of childhood depression and anxiety on suicidal thoughts in elementary, middle, and high school students according to developmental stage. Unlike existing studies that individually examined the development of elementary, middle, and high school students, this study aimed to suggest intervention measures to prevent suicidal thoughts in childhood by comparing the development stages of elementary, middle, and high school students. The data for this study are data from the 10th (2015), 13th (2018), and 16th (2021) Children's Supplementary Survey of the Korea Welfare Panel, which includes elementary school students in the 10th round, middle school students in the 13th round, and high school students in the 16th round. A total of 1,174 people were used for analysis. The research model was analyzed using the SPSS program and PROCESS macro. Looking at the results of the analysis, first, as a result of confirming the mediating effect of feelings of withdrawal in the relationship between depression and anxiety in childhood and suicidal thoughts in adolescence according to developmental stage, it was confirmed that there was a partial mediating effect in middle school and high school. Second, in the relationship between depression and anxiety in childhood, feelings of withdrawal, and suicidal thoughts in adolescence according to developmental stage, the mediated moderating effect of self-esteem was confirmed in middle school and high school students, but it was confirmed that there was no moderating effect of self-esteem in elementary school students. The above research results were discussed based on previous research, and based on these results, an effective intervention plan was proposed to reduce suicidal thoughts in adolescence.
Integrative approach in managing oral lichen planus
Authors: Sagarmani  , Saawarn Nisheeth
Published: June 2024

Oral lichen planus (OLP) is a well-known chronic inflammatory disorder which is linked with alteration in functioning of cell-mediated immune function. It is characterised by repeated exacerbations, prolonged evolution, pain, resistant to treatment, thus affecting the quality of life of patients. The present review focuses on treatment strategies of OLP and how these methods improve the quality of life of patient. The main aim of OLP therapy is reducing the symptoms and eliminating the occurrence of mucosal related lesions, along with reduction of oral cancer risk. The common treatment modalities are laser, ultraviolet irradiation, immunomodulatory agents, corticosteroids, retinoids etc.
Artificial intelligence in robo dentistry: A double-edged sword
Authors: Kaur Kuljit
Published: June 2024

As technology continues to advance at an unmatched pace, artificial intelligence (AI) has become an omnipresent presence in our lives. Artificial intelligence (AI) is a technology that utilizes machines to imitate intelligent human conduct that is because of its intense capabilities in data analysis, and virtual algorithms. These capabilities can increase the efficacy of AI robots in dental diagnosis, and treatment plans and also to assess the prognosis of various oral diseases. Apart from benefits, there are several unwanted consequences while doing the AI-assisted operation, the dentist is still required to monitor the whole process. In various case scenarios like data error, any circuit interruption, or some other unexpected conditions, if something happened, the consequences would be unimaginable. Robodentistry is like a coin having two faces. One face helps patients in a better way like a dentist but the other face when turned up, can pose big problems. So, still, more researches are required before thinking that robots can do the job autonomously in dentistry.
Study of the neuroprotective properties of the heteroreceptor EPOR/CD131 agonist of peptide structure in tau-proteinopathy modeling
Authors: Stepenko Yulia V. , Shmigerova Veronika S. , Kostina Darya A. , Shcheblykina Olesya V. , Zhernakova Nina I. , Solin Alexey V. , Koroleva Natalia V. , Markovskaya Vera A. , Dudnikova Olga V. , Bolgov Anton A.
Published: June 2024

Introduction: Tau proteinopathy is a pathology associated with the activation of post-translational modifications and interactions of pathophysiological cascades of neuroinflammation with hyperphosphorylation of Tau aggregates. Therefore, preference is given to agents that have properties in reducing or slowing down the processes of neuroinflammation and post-translational modifications in the brain.
Materials and Methods: The study was conducted on male and female homozygous individuals of a transgenic murine line with overexpression of mutant human Tau gene (P301S) and a background wild mouse line C57Bl/6J. To assess the progression of Tau proteinopathy, behavioral tests were used at two control time points, and the last one measured the level of neuroinflammation markers and tau-proteinopathy.
Results and Discussion: In the group of P301S mice treated with ARA-290, an improvement in the phenotypic picture of Tau proteinopathy was demonstrated compared with intact animals. In the Barnes circular maze test, mice showed a decrease in the total distance traveled and the latent time spent on the platform, which indicates a rapid entry into the shelter. In the O-shaped maze test, the group maintained a fairly high level of spontaneous exploratory behavior. In the vertical rod test, the animals recorded the best time indicators that they needed to turn and maintain balance compared to the intact group. A statistically significant decrease in the level of GSK-3β and an increase in CDK5 and PP2A were revealed, which indicates a dephosphorylating effect on Tau protein, as well as markers of neuroinflammation. NF-KB and TNF-α were significantly reduced by 57% and 32%, respectively, compared to the intact group.
Conclusion: In the model of transgenic P301S murine line with overexpression of the mutant human Tau gene, the peptide agonist of the EPOR/CD 131 heteroreceptor demonstrated neuroprotective properties, which were confirmed by indicators of behavioral tests and markers of neuroinflammation and tau-proteinopathy.
A Design and Implementation of an Online Video Lecture System based on Facial Expression Recognition
Authors: Seo Seung Ho , Kim Min Young , Kim Yong
Published: June 2024

Real-time online education facilitates education without requiring instructors and students to be physically present in the exact location, allowing for interactions similar to face-to-face teaching. However, when many students participate simultaneously, instructors face challenges, such as spending a lot of time understanding each student's learning status. Mainly, systems utilized for real-time online education, initially developed for business meetings, have limitations when repurposed for educational uses. Therefore, this paper presents the design and implementation of a video lecture system for real-time online education based on facial expression recognition. The system is a video lecture system based on Facial Expression Recognition, implemented with a web browser method, a classroom tool platform supporting teacher-student interaction, and facial expression recognition features based on an artificial intelligence engine. Engagement metrics utilize fundamental values like facial recognition, total learning time, and video playback to measure student engagement through facial expressions. Additionally, structured numerical data such as eye-tracking, motion tracking, drowsiness tracking, speaking, effective chatting, hand-raising, polling, and screen sharing are weighted and aggregated for calculation. Weights can be adjusted according to the nature of the lecture, such as discussion-based learning or cooperative learning. The system calculates student engagement levels, categorizing them as 'Active (90 points)', 'Moderate (80 points)', and 'Insufficient (70 points)', and is designed to provide this data to instructors asynchronously. Furthermore, a focus group interview was conducted with Edtech experts to validate the implemented system, and positive responses were obtained.
Development of Classification Method for Lecturer Area of Expertise Based on Scientific Publication Using BERT
Authors: Didi Rustam  , Suhendra Adang , Harmanto Suryadi , Suhatril Ruddy , Saputra Dwi Fajar , Tafsili Rusdan , Prasetya Rizki
Published: June 2024

Implementing the Artificial Intelligence concept in higher education can be utilized in the context of Human Resource (HR) talent management. The lecturer portfolio provided by the Integrated Resource Information System (SISTER DIKTI) is expected to give an overview of the profiles of all lecturers and map competencies based on groups of fields of knowledge. However, the map of scientific fields based on SISTER data currently available is still subjective. The data is in the form of a group of lecturers' chosen fields of science, independently selected by each lecturer to recognize their expertise. This study discusses the problem of processing unstructured SISTER data. It looks for mapping solutions and classification methods by developing a strategy for classifying groups of scientific fields from unstructured data input. It is necessary to identify the suitability of the chosen field of science compared to that developed through the tri-dharma through identification based on a mapping of the group of fields that can be extracted from the tri-dharma activity, in this case, research represented by scientific publications recorded on SISTER. Therefore, we need an appropriate model to measure similarity, which can then be classified based on abstract documents and scientific publication titles for the classification of scientific fields using NLP based on classification run on DGX A100. This study aims to develop a classification method from titles and abstracts. Scientific publications contained in SISTER are unstructured data, so a corpus is formed to identify the lecturer's field of science. The results show that the classification method developed in this study can measure the similarity of lecturer publications based on abstracts and titles through a vector formation process based on bidirectional encoders and also produces a deep learning model to classify 24 categories of fields of science with an accuracy of 95,0345 percent on training data and 92.876 percent on the test data.
Inclusion of Dividends in the Customs Value of Goods: Aspects of the Judicial Practice
Authors:   Postgraduate Student of the Department of Financial, Banking and Customs Law Named after Professor Nina I. Khimicheva of the Saratov State Law Academy, Markov Dmitry V.
Published: June 2024

The article deals with the regulation of the customs value of goods, explores the legal nature of dividends as one of the elements of the customs taxation system in the law of the EAEU. The author analyzes the judicial practice on the possibility of including the amounts of dividends in the customs value of goods, formulates proposals for amendments to the legislation regulating customs relations in the EAEU in order to increase the legal certainty of regulating the customs value of goods on transactions concluded between interdependent persons.
The Concept and Classification of Forms of Legal Coverage of Tax Security of the State
Authors:   Leading Research Scientist of the Center for Tax Policy of the Financial Research Institute of the Ministry of Finance of the Russian Federation, LL.D., Associate Professor, Ponomareva Karina A. , Maslov Kirill V. ,   Expert of the Center for Tax Policy of the Financial Research Institute of the Ministry of Finance of the Russian Federation, Associate Professor of the Department of State and Municipal Law of the Dostoevsky Omsk State University, PhD (Law), Associate Professor
Published: June 2024

The article proposes a classification of forms of legal provision of tax security of the state. It is noted that the forms of ensuring tax security used by each entity are determined by the competence of this entity. Therefore, it is important to fully reflect in administrative and tax legislation, as well as in by-laws, the forms available to all public authorities involved in this activity and private entities assisting them. Law-making, legal implementation and law enforcement forms of ensuring tax security are highlighted.
Issues of Application of the Median Value of the Market Interval in the Regulation of Transfer Prices
Authors:   Associate Professor of the Department of Taxes and Tax Administration of the Faculty of Taxes, Audit and Business Analysis of the Financial University under the Government of the Russian Federation, PhD (Economics), Knyazeva Anastasia V.
Published: June 2024

Material changes in the tax regulation of transfer pricing have occurred in the early 2024, such changes include the introduction of the median value of the market price interval (financial parameters). This is a new instrument in the regulation of transfer pricing, its introduction was not justified in the bill discussion period, but its effect is significant for tax obligations of Russian companies. The new instrument in the transfer pricing system creates additional risks for taxpayers, as well as for the state in terms of economic relations with regard to timely and full calculation and payment of taxes, as well as for parties to international economic activities and internal relations. This predetermines the research subject: the conditions of and procedure for applying the median value for the purposes of tax control of intracompany transaction prices. The research methodology is based on an analysis of transfer pricing recommendations of the ОECD in АННОТАЦИИ Налоги № 2-2024 47 АННОТАЦИИ terms of applying statistical tools to determine the price of the transaction under analysis, provisions of foreign regulations that determine the pricing procedure in transactions between related entities. Special attention is paid to an analysis of foreign court judgments on determination of the market price of intracompany transactions. An analysis of the ОECD recommendations has given an opportunity to single out obligatory conditions for the application of the median value. The author has identified a tendency towards harmonization of approaches to using the median value in foreign countries and the general trend to clarifying regulations in 2022-2024. The judicial practice shows that irrespective of the activity type or type of transactions performed by group subdivisions, courts award uniform judgments in terms of applying the median value and take into account the ОECD recommendations when passing a judgment. The paper concludes that Russian taxpayers face an additional tax risk rooted in the differences in the approach towards the application of the median value in the Tax Code of the Russian Federation and the OECD Transfer Pricing Guidelines for transnational corporations and tax administrations used to regulate taxation of transactions between related entities in explanations of tax authorities and the judicial practice. The scientific novelty of the study lies in the determination of tendencies towards applying the median value for transfer pricing purposes, evaluation of tax consequences of the novelty for Russian taxpayers.
On Improvement of Tax Incentives in the Radioelectronic Industry
Authors:   Associate Professor of the Department of Taxes and Tax Administration of the Financial University under the Government of the Russian Federation, PhD (Economics), Associate Professor, Tikhonova Anna V.
Published: June 2024

The article suggests targeted tax incentives for entities of the radioelectronic industry depending on their size. The author assesses the fiscal effect of proposals for the development of value added tax. In the final part of the study, the author suggests methods of transformation of the taxation system on product life cycle stages in critical, primary, non-resource-based industries.
Scientific works. Russian Academy of Legal Sciences
Authors:   Head of the Department of Constitutional Law of the Moscow State Institute of International Relations (University) of the Ministry of Foreign Affairs of the Russian Federation, Rector of the A.S. Griboyedov Moscow University, Member of the Russian Academy of Education, Honored Lawyer of the Russian Federation, LL.D., Professor, Grib Vladislav V.
Published: June 2024

The collection presents the works of members of the Russian Academy of Law Sciences (RAUL) and the materials of the XXIV International Scientific and Practical Conference "Legal Support of Russia's Sovereignty: Problems and Prospects", organized by the Faculty of Law of the Lomonosov Moscow State University, the Russian Academy of Law Sciences, the O.E. Kutafin Moscow State Law University, the Moscow branch of the Association of Lawyers of Russia with the participation of legislative, executive and judicial authorities, public associations of lawyers, law schools and scientific legal institutions, which took place in Moscow from November 21 to November 24, 2023.
Inteligentne Systemy Transportowe – możliwości i efekty ich zastosowania w miastach – przykład Łodzi
Authors: Szymczyk Maria
Published: June 2024

Celem głównym rozdziału jest przedstawienie korzyści i możliwości płynących z funkcjonowania Inteligentnych Systemów Transportowych w Łodzi. W pierwszej części tego rozdziału wyjaśnione zostały założenia koncepcji Smart City i jej istota we współczesnym świecie. Następnie poruszona została kwestia Inteligentnych Systemów Transportowych i ich ścieżki rozwoju. Część empiryczna przedstawia nowoczesne systemy transportowe wprowadzone w Łodzi i efekty ich zastosowania. Zaprezentowano również wyniki badania ankietowego przeprowadzonego wśród kierowców poruszających się po Łodzi i osób użytkujących tamtejszy publiczny transport zbiorowy.
NLRP3 inflammasomes as a target for hesperidin and diosmin flavonoids in varicose vein disease and its complications
Authors: Astashkin Evgenii I. , Glezer Maria G.
Published: June 2024

Varicose vein disease of the lower extremities is an inflammatory disorder with abnormal structure and functional activity of the venous valves, venous walls and cells, as well as with abnormal activity of the infiltrating leukocytes. The abnormally changed varicose vein are characterized by increased venous pressure, blood accumulation and congestion, ischemia, and metabolic and energy turnover derangement, which result in clinical manifestations of complications, such as pain, edema and formation of trophic ulcers. For many years, flavonoids have been used to treat varicose veins. The most effective flavonoids used in varicose vein disease and its complications, are hesperidin and diosmin, as well as their combinations.
The review sets forth the state-of-the-art knowledge on the universal inflammatory processes playing a leading role in the pathophysiology of many cardiovascular disorders, including venous ones.
In the recent years, it has been found that one of the main causes of inflammation is the formation of intracellular protein complexes (inflammasomes), which both produce a set of proinflammatory cytokines and are responsible for their excretion from the cells. In addition, inflammasomes control the development of regulated necrosis (pyroptosis) that takes part in the process of ulceration. The inflammasome activity can be modified by various mechanisms, of which the gene independent synthesis of the inflammasomal proteins has been recognized as the leading one. It has been shown that flavonoids inhibit the activation of a key factor NF-kappa B and suppress the synthesis of proteins, including NOD-like receptor protein 3 (NLRP3) inflammasome components, decrease the expression of NLRP3 receptor, protein ASC and caspase 1, as well as diminish interleukin 1 beta, interleukin 6 and tumor necrosis factor-alpha expression. Thus, this is the explanation of positive effects observed with the use of hesperidin, diosmin and their combination in clinical practice.
Tradition and Meaning of Czech Education
Authors:   East European and Balkan Institute, Yu Sunbee
Published: June 2024

The Czech Republic has recognized the importance of education from an
early age and has made efforts to establish concepts and ideas for this purpose.
In the case of the Czech Republic, the main ideas of Czech education were
established through the Middle Ages and the Baroque period, and that tradition
was unified in the late 19th century and became the fundamental ideology of
policy.
Although this tradition was temporarily interrupted through the process of
communism and changes occurred in Czech educational policies after the
transition, the educational ideas and traditions that underlie them remain
unchanged.
The ideological and philosophical background of Czech education begins with
Jan Hus, who set an example of the fundamental spirit of education, which is the
restoration of humanity, and of putting this into practical action. And this idea
developed through Petr Chelčický, who laid the framework for the idea of peace
through ‘non-violence’. This development continues through J. A. Comenius(J. A.
Komenský), who has the title of father of pedagogy, who emphasized the
‘pan-educational thinking’ that humans can and should be educated without
conditions, regardless of gender, race, and ethnicity. His ‘peace education
ideology’ and pedagogical theory and system became the starting point for
creating ‘international cooperation and system’ in education. The ‘humanistic
ideas’ and efforts toward education that they emphasized have been passed down
to modern President T. G. Masaryk, and form the core ideas of Czech education
in the future, and have a powerful influence in forming the consciousness and
identity of the Czech people.
When the Czech Republic became a Soviet bloc, there was a time when it
deviated from its traditions and legacy, such as the centralized education system,
but after the reform, it sought to return to an essential and fundamental system,
and the change was also based on the spirit of Hus and Comenius of the past.
Romanian Education in Transition and Integration
Authors:   East European and Balkan Institute, Kim Jeong Hwan
Published: June 2024

Due to changes in ideology and policy, the Romanian education system is divided into three distinct periods: the period from modern times to 1944, the socialist education system from 1944 to 1989, and the great transition period after 1989. While the first period was characterized by the expansion of the public education system and progress in improving curriculum and teacher education programs, the second period was characterized by the nationalization of all educational institutions, extreme centralization through a unified basic curriculum and textbooks, excessive politicization, and an emphasis on abstract teaching methods.
The period of socio-political and economic change in Romania after 1989 led to the reform of the education system, with pressures on the market economy and the restoration of democratic principles, pressures imposed by the Bologna Process. During the transition period, there were many changes in the curriculum, public and private educational institutions, retraining and mobility of teaching staff, and infrastructure. The responses of the Romanian education system to new variables and opportunities were partly immediate and partly gradual, depending on the interlocking circumstances and interests.
The reform process, including new challenges and social risks during the transition period, was difficult, slow, and complex, influenced by economic, political, and social conditions. However, Romanian education during the integration transition period symbolized by the Bolona Process and EU membership became a stepping stone for successful reform. In this process of integrated transformation, Romanian education continues contemporary ongoing educational reforms by embracing a unified three-level degree program (Bachelor’s, Master’s, Doctoral programs), ECTS (European Credit Transfer and Accumulation System) & EQF (The European Qualifications Framework), as well as providing internationalization and mobility programs in higher education.
Comparative analysis of separation techniques in the treatment of medial ventral hernias
Authors: Stolyarov E. A. , Grachev B. D. , Alekseev D. G. , Bezrukova M. A. , Ishutov I. V.
Published: June 2024

Relevance. Tension-free herniolasty of the anterior abdominal wall is currently the accepted standard for large ventral hernia repairing. The implementation of this approach has been marked by a significant improvement in treatment outcomes. The issues of improving the quality of life of patients after surgery and their effective rehabilitation through the application of the optimal technique of tension-free hernioplasty are now at the forefront.

Objective. To compare the immediate and long-term results of treatment of patients with large postoperative midline ven­tral hernias using anterior and posterior techniques of separation of abdominal wall components.

Object and methods. 114 patients with large postoperative midline ventral hernias were divided into two groups: the patients of the first group (38 patients) underwent hernioplasty using the anterior separation technique, and the patients of the second group (76 patients) - posterior separation. We evaluated the immediate (complica­tions in the area of surgery, duration of surgical wound drainage and duration of hospitalization) and long-term (functional restoration of the abdominal wall) results of treatment with subsequent comparative analysis of data between the groups using descriptive statistics methods.

Results. The present study is the first to compare the immediate and long-term results of using anterior and posterior techniques for separation of anterior abdominal wall components during surgery for midline ventral hernias. It was found that both variants demonstrate good immediate and long-term results in the treatment of patients with median postoperative ventral hernias of large size. At the same time, the anterior separa­tion technique is accompanied by a significantly higher number of complications and, accordingly, is characterized by a higher risk of their de­velopment, as well as requires a longer stay of the patient in the hospital.
Fentanyl-Induced cerebrocardial syndrome
Authors: Akhmatkhanova L. Kh.-B. , Kovaleva E. A. , Aliev I. S. , Korigova Kh. V. , Shevchenko E. V. , Simonova A. Yu. , Ramazanov G. R.
Published: June 2024

The clinical case is presented to demonstrate the importance of differential diagnosis of cerebral circulation disorders in patients with acute or chronic toxic effects of psychoactive substances. In the presented observation, a 50-year-old patient was taken to the N.V. Sklifosovsky Research Institute of SP with depression of the level of wakefulness to deep deafness, denies the fact of using psychoactive substances when collecting anamnesis, bilateral myosis, diffuse decrease in tone in all extremities. Computed angiotomography of the brain, transcranial dopplerography, magnetic resonance imaging of the brain, electroencephalography were performed – without obvious diagnostic findings. During a detailed examination in a neurological clinic, no data were obtained for a violation of cerebral circulation, a chemical and toxicological examination of urine and blood was performed, fentanyl was detected in biological media. Based on the literature data, however, damage to the nervous system usually occurs due to chronic intoxication and it is not always possible to detect psychoactive substances in biological environments. Due to respiratory depression, the patient was intubated and was on artificial ventilation for 72 hours until spontaneous respiration was restored. After repeated demand, the patient admitted the fact of using fentanyl allegedly to relieve pain, after which he refused further treatment. The conclusion is the need for a chemical and toxicological study of biological media in the case of a violation of consciousness of unclear genesis, however, damage to the nervous system usually occurs due to chronic intoxication and it is not always possible to detect psychoactive substances in biological media.
Features of indicators of the cardiovascular system and psychophysiological parameters in medical students during the period of examination session and seminars lessons
Authors: Pavlova O. N. , Budaev A. I. , Pavlenko S. I. , Kovalyov A. M. , Makarova-Gorbacheva E. V.
Published: June 2024

The cardiovascular system is one of the key systems of the body, which determines the boundaries of a person's physical and mental performance and ensures the adaptation of students' bodies to the educational process. At the same time, various factors can cause tension in students adaptation mechanisms, one of which may be the period of the examination session.

Purpose: to identify differences in the perfor­mance of the cardiovascular system and psychophysiological parameters during the examination session and during seminar classes among medical students of the second year of study.

Object and methods: The study was conducted on 22 second-year students of both sexes. The subjects heart rate and blood pressure were studied and the values of the index of functional changes, adaptive potential and Robinson's index were calculated. The psychoemotional component was assessed according to the results of the Spielberger-Hanin test, the Guilford test and work efficiency, which was calculated based on the time spent working with Schulte tables.

Results: indicators of the cardiovascular system showed an increase in the tension of adaptation processes during seminar classes, compared with the period of the examination session, for example, the IFC values statistically significant changed from 2.12±0.09 to 2.25±0.07 (p<0.05 ). At the same time, there was a tendency to in­crease situational anxiety and a significant increase in the time spent working with Schulte tables from 34.05±2.73 to 44.01±3.1 8 (p<0.05).

Con­clusion: the data obtained allow us to make an assumption about the stress in the adaptation mechanisms of second-year medical students that arise regardless of the examination session, which indicates the need to continue the study in order to identify stress factors.
Impactos das práticas culturais e religiosas sobre a biodiversidade em comunidades tradicionais do Semiárido brasileiro
Authors: Brandão Maria Aparecida Ventura , Santos Carlos Alberto Batista , Andrade Wbaneide Martins de
Published: June 2024

A busca pela cura do corpo e da alma nas comunidades do Semiárido brasileiro advém de uma tradição vivenciada entre os sujeitos, que habitam, principalmente, os espaços rurais. O presente artigo tem como objetivo indicar os impactos produzidos sobre a biodiversidade a partir das práticas culturais e religiosas, das comunidades da Ilha do Massangano, povoado rural negro pertencente ao município de Petrolina, PE e Lage dos Negros, quilombo pertencente ao município de Campo Formoso, BA. Assim sendo, a investigação decorre de fundamentos étnicos e culturais da sociodiversidade desses grupos tradicionais. Para tanto, foi utilizada a técnica denominada snowball sampling, ou “Bola de Neve”, como uma ferramenta metodológica para seleção dos participantes que integraram a investigação. Os dados foram obtidos por meio de entrevistas semiestruturadas e aplicação de questionários envolvendo as lideranças religiosas e os participantes dos grupos culturais locais. A análise que guiou o estudo foi à análise de conteúdo. Este artigo vem demonstrar toda uma compreensão de devoção ao meio ambiente, e seus elementos e os resultados apontaram que as práticas religiosas e culturais que utilizam recursos naturais, como a fauna e a flora, não trazem efeitos negativos à biodiversidade local. Ao manterem vivas suas práticas culturais e religiosas, essas comunidades demonstram consciência do valor de seus ecossistemas e daquilo que eles representam em seus contextos. A partir dessas noções, as comunidades quilombolas ensinam ao mundo que é preciso garantir vida para suas gerações futuras.
Multistakeholder governance and community engagement in urban greening
Authors: Guaraldo Eliane
Published: June 2024

Simone Borelli leads the Forestry Division at the Food and Agriculture Organization (FAO-ONU). He is one of the creators of the Tree Cities of the World Program and was invited to a conference at the “Congresso Brasileiro e Ibero-Americano de Arborização Urbana. Urban Forestry in the Decade of Ecosystem Restoration”, in sept-oct 2021. This event took place at the Federal University of Mato Grosso do Sul, and was promoted by the Graduate Program in Natural Resources (PGRN_UFMS), in partnership with the Graduate Program in Local Development, from the Catholic University D. Bosco  (PGDL_UCDB) and the Brazilian Society of Urban Forestry (SBAU), the Brazil Chapter of International Society of Arboriculture (ISA). The interview was conducted after the event ended and reflects its commitment to the theme of green infrastructure and community involvement.
Governança por múltiplos atores sociais e engajamento da comunidade no verde urbano
Authors: Guaraldo Eliane
Published: June 2024

Simone Borelli é líder da Divisão Florestal da Organização das Nações Unidas para Agricultura e Alimentação (FAO-ONU). É um dos idealizadores do Programa Tree Cities of the World e foi convidado para ministrar uma conferência no “Congresso Brasileiro e Ibero-Americano de Arborização Urbana. Arborização Urbana na Década da Restauração dos Ecossistemas”, em setembro-outubro de 2021. O evento aconteceu na Universidade Federal de Mato Grosso do Sul (UFMS) e foi promovido pelo Programa de Pós-Graduação em Recursos Naturais (PGRN-UFMS), em parceria com o Programa de Pós-Graduação em Desenvolvimento Local, da Universidade Católica Dom Bosco (PGDL-UCDB) e da Sociedade Brasileira de Arborização Urbana (SBAU), o Capítulo Brasil da International Society of Arboriculture (ISA). A entrevista foi realizada após o término do evento e reflete seu compromisso com o tema Infraestrutura Verde e envolvimento de comunidades.
Сучасні технології приховування облич людей за допомогою object tracking на базі YOLOv5 та DeepSort
Authors: Щур А. , Польшакова О.
Published: June 2024

Об’єктом дослідження є система автоматизованого розмиття людських облич на відео. В даній статті зроблений детальний огляд сучасних технології та принципів відслідковування об’єктів на відео з присвоюванням їм елементів унікальності. Так як наразі більшість відео редакторів все рівно більшу частину роботи залишають користувачеві, було вирішено провести оптимізацію даного процесу. Метою даної роботи є зниження часових витрат на виконання процесу приховування людських облич на відеофайлах. Для досягнення такої цілі пропонується використовуватисучасний детектор – згорткову нейронну мережу YOLO та алгоритм відслідковування об’єктів – DeepSORT, що використовує класичні підходи фільтрування вхідних даних та прогнозування положення об’єкта у просторі а також сучасну нейронну мережу, що здатна розрізняти зовнішність людей. В результаті даної роботи, серед безкоштовних аналогів в мережі інтернет, було досягнуто прискорення розмиття облич до 20%, що є досить непоганим результатом.
Бібл. 8, іл. 10, табл. 3
A Fight for ‘The Icy Africa’? Greenland Caught Between the Colonial Past, the U.S. Arctic Interests and the EU Strategic Autonomy
Authors: Belukhin N.
Published: June 2024

The article deals with the foreign policy priorities of Greenland as they are reflected in the perception and rhetoric of the contemporary Greenlandic elites. The special focus is on the current stage of the autonomous territory’s development, in particular the possibility of concluding a free association agreement, as envisaged in the draft constitution of Greenland, published in April 2023. With the 2019–2023 period as a basis, the article provides an insight into the key events of the following areas of Greenland’s foreign policy contacts: the Danish-Greenlandic relations, Inuit internationalism where the bonds with the Inuit of Canada are of most significance, Greenland's place in the US Arctic strategy and its great-power competition with China, and, finally, the increased interest of the EU and certain European countries in fostering relations with the Danish Arctic autonomy, which can contribute to developing the EU strategic autonomy. The study of the political discourse has shown that Greenlandic elites have been successfully using colonial ‘traumas’ and a growing circle of contacts with major external actors to exact pressure on Copenhagen and expand its political leverage despite the absence of substantial economic successes comparable to those achieved by the Faroe Islands, another Danish autonomy. Greenland’s desire to increase its own actorness on the international scene makes it difficult for Copenhagen to use the ‘Greenland card’ both in its relations with the USA to revitalize the special relations with the key ally and as a contribution to the EU strategic autonomy. The Danish leadership is thus entrapped by Greenland’s own economic and foreign policy potential, since the widespread use of Greenland in relations with the EU, NATO, the United States and other actors of world politics could potentially lead to the renewed mounting pressure on Copenhagen from Greenland and to the autonomy’s further alienation and diplomatic self-sufficiency.
Development and Evaluation of Value Enriched Sattu Mix for under nutrition
Authors: Sai Vilas Deshpande , Chaitali Sandeep Kotwal , Varad Vilas Deshpande
Published: June 2024

Sattu is flour consisting of a mixture of ground pulses and cereals from India. The process of preparing sattu is ancient and is popular over a wide area of India, particularly Bihar. It is also known as "desi horlicks" in the state of Bihar. Sattu is known as the 'poor man's protein.' It's essentially a flour-like substance that's abundant in nutrients and known as the "energy powerhouse." Sattu is a wonder flour that can be consumed uncooked. The cooling properties of sattu make it a perfect summer choice. It has low glycemic index and high fiber content. In current study traditional sattu powder is enriched with incorporation of nutritionally rich millets. Value enriched sattu mix was standardized and analyzed for their sensory, nutritional evaluation and storage study. Four variations of sattu mix was developed i.e. T1 controlled trail and experimental T2, T3, and T4 trail. Sensory evaluation of developed value enriched sattu mix tails and controlled trail was made in terms of their colour, taste, flavor, texture and overall acceptability using five point ranking scale. Results showed that among all the trails prepared, T4 was most accepted in terms of all the sensory parameters by semi trained panel members. The nutritional analysis of accepted trail of value enriched sattu mix depicted that it has high amount of crude fibre, calcium, total minerals and crude protein content. Developed value enriched sattu mix was stored in an air tight container at room temperature for 3 months. It was concluded that prepared value enriched sattu mix is very beneficial for undernourished patients and also helpful for weight reduction.
Effect of Seed Priming on Agronomic Performance of Rice (Oryza sativa L.) Variety C26
Authors: Badiel Badoua , Koné Tchoa , Pascal Kihindo Adama , Ouedraogo Nestor , Koné Etmongomaké
Published: June 2024

Rice is a staple food for many people and a source of currency for many farmers. However, in West Africa, yields remain low. One of the reasons is the unsuitability of cultivation techniques, which results in heterogeneous germination of seedlings and low yields. The aim of this study was to evaluate the agronomic performance of rice variety C26 after seed priming. Rice grains were primed in various solutions. The resulting seeds were sown in a randomized block design with three replications in each cropping system (lowland and rainfed). Treatments were a control (no priming) and seed priming (NaCl; sucrose and Water). Sucrose and water priming were better in both growing systems. The NaCl system recorded the lowest agronomic parameter values. In the lowland, the emergence percentage was 95%. Emergence time at 50% (T50) varied between 6.6 and 11.10 days. The number of thalli and plant height increased from 7.22 to 9.50 thalli and from 30.28 to 50 cm respectively. Yield improved from 2362.17 kg/ha for the control to 3666.67 with sucrose priming and 4222.50 kg/ha with water priming, an increase of almost 50%. In rainfed conditions, emergence percentages ranged from 90 to 96%. T50 varied between 3.27 and 4.9 days. The number of thalli and plant height increased from 6.78 to 8.44 thalli and from 31 to 34 cm respectively. Yield increased by around 50%, from 1353.83 (control) to 2400.81 kg/ha with sucrose and 2844.62 kg/ha with water. The study shows that priming with water and sucrose significantly improves the agronomic performance of rice variety C26.