bluuebunny/crossref_metadata_2025 huggingface dataset:
Клинические и иммуногенетические особенности течения атопического дерматита
Authors: Litus V. I. , Derkach N. V. , Litus O. I.
Published: December 2018

Актуальность. Атопическим дерматитом (АД) страдает 10-20% педиатрического и 1-3% взрослого населения. Распространенность АД в течение последних 30 лет выросла во всем мире, включая около пятой части населения развитых стран. Атопический дерматит или атопическая экзема является хроническим воспалительным заболеванием кожи, представляет серьезную проблему общественного здоровья во всем мире. Эта болезнь имеет существенный социально-экономическое бремя частично из-за отсутствия эффективного лечения, способного контролировать болезнь в долгосрочной перспективе. Целью исследования стал анализ современных представлений патогенеза и особенностей течения атопического дерматита. Материалы и методы. В процессе исследования были использованы методы семантического оценивания научных документов, а также методы структурного и логического анализа. В исследовании использованы материалы планирования и выполнения диссертационной работы по специальности 14.01.20 - кожные и венерические болезни и 14.03.08 - иммунология и аллергология. Результаты. В статье представлены результаты анализа обзора современных научных исследований патогенеза и особенностей течения атопического дерматита. Проанализированы последние направления научного поиска, научная новизна, теоретическое и практическое значение достижений научных исследований в практическом здравоохранении. Освещены подходы к современной профилактики и лечения атопического дерматита. Выводы. Наше настоящее понимание о АД резко изменилось на протяжении последних годов, главным образом, из-за значительного прогресса в эпидемиологии и генетике, огромный прорыв в понимании концепции атопического марша, а также раскрытия новых аспектов анамнеза болезни и изучения форм АД, которые персистируют в течение всей жизни. Четкое определение различных клинических фенотипов, с одной стороны, и потенциальных биомаркеров с другой являются ключевыми элементами для успешного развития новых и персонализированных терапевтических подходов у больных АД.
Анализ факторов, влияющих на доступность опиоидных анальгетиков для использования в медицинских целях
Authors: Datsiuk N. O. , Bratsun O. P. , Volokh D. S. , Gubskyi Yu. I.
Published: December 2018

Актуальность. Около 75 % населения мира из более 100 стран не имеют надлежащего лечения сильной боли из-за ограниченной доступности опиоидных анальгетиков (ОА), которые являются жизненно необходимыми лекарственными средствами (ЛС) при лечении сильного болевого синдрома и оказании паллиативной помощи (ПП). Целью исследования было изучение факторов, влияющих на доступность ОА для осуществления адекватного обезболивания паллиативных пациентов на основе анализа международных и отечественных литературных источников. Материалы и методы. Поиск литературы осуществлялся в базах данных Pubmed, Google scholar и Национальной библиотеки Украины имени В. И. Вернадского. Результаты. Проблема доступности ОА является мультифакторной и обусловлена преградами, аналогичными во всех странах, в том числе и в Украине. Среди них: низкий приоритет проблемы облегчения боли в системе здравоохранения и низкая осведомленность среди медицинского персонала; значительно преувеличенные опасения относительно возможности развития привыкания и побочных реакций при приеме ОА; чрезмерные ограничения, введенные национальными органами по контролю за указанными препаратами; ограниченный ассортиментом этих лекарственных средств, очень низкое количество аптек, осуществляющих их реализацию, а также высокая цена опиоидов.
Клинико-фармакологическое, классификационно-правовое и номенклатурно-правовое распределение лекарственных средств для фармакотерапии депрессии у комбатантов (F 32-33)
Authors: Shapovalov V. V. , Gudzenko A. O. , Shapovalova V. O. , Shapovalov V. V.
Published: December 2018

Актуальность. Формирование психических расстройств в зоне военного конфликта происходит в чрезвычайных ситуациях, которыми выступают боевые действия, что приводит к возникновению стрессовых расстройств, а в дальнейшем после возвращения в привычные условия жизни может привести к декомпенсации расстройств личности, посттравматическим стрессовым расстройствам, депрессии, суицидам и самоубийствам. Цель исследования. Провести клинико-фармакологическое, классификационно-правовое и номенклатурно-правовое распределение лекарственных средств для фармакотерапии депрессии у комбатантов с определением параметров их режима контроля. Материалы и методы. Для проведения исследования были использованы действующие нормативно-правовые и инструктивно-методические документы, Государственный реестр лекарственных средств Украины, научные источники, инструкции для медицинского применения лекарственных средств, интернет-ресурсы. Использовались нормативно-правовой, документальный и судебно-фармацевтический методы анализа. Результаты. В статье проведено клинико-фармакологическое, классификационно-правовое и номенклатурно-правовое распределение лекарственных средств с определением параметров их режима контроля по кодам F 32-33 МКБ-10 для фармакотерапии депрессии у пациентов-комбатантов, которые в учреждениях здравоохранения различных уровней получают медицинскую помощь и фармацевтическое обеспечение. Выводы. Установлено, что для фармакотерапии депрессии в учреждениях здравоохранения назначаются лекарственные средства, которые: по клинико-фармакологическому признаку относятся к АТС-кодам «N04B», «N05А» и «N06A»; по классификационно-правовому признаку – к общей группе; по номенклатурно-правовому признаку – к рецептурной группе. Определено, что обращение антидепрессивных и антипсихотических лекарственных средств для фармакотерапии депрессии у комбатантов в медицинских учреждениях осуществляется на основании лицензии на медицинскую практику, а в аптечных учреждениях – на основании лицензии на оптовую и розничную торговлю лекарственными средствами. Внедрение в работу учреждений здравоохранения параметров режима контроля лекарственных средств для фармакотерапии депрессии является актуальным для врачей-психиатров, врачей-наркологов, врачей общей практики и обеспечит надлежащую организацию порядка их обращения на этапах назначения, выписки, хранения, учета, контроля качества и отпуска в соответствии с требованиями действующего законодательства.
Институт семейной медицины - лидер развития первичной медицинской помощи на принципах семейной медицины в Украине
Authors: Shekera O. G. , Medvedovska N. V. , Tkachenko V. I. , Zhesterov A. A.
Published: December 2018

No abstract
Итоговое резюме KDIGO 2018 по гепатиту С для рекомендаций по ХБП: достижения в оценке и менеджменте
Authors: Morales Jose´ M. , Martin Paul , Di Mengyang , Earley Amy , Gordon Craig E. , Balk Ethan M. , Silva Marcelo O. , Pol Stanislas , Patel Priti R. , Jadoul Michel , Lai Ching-Lung , Kasiske Bertram L. , Kamar Nassim , Jha Vivekanand , Izopet Jacques , Fabrizi Fabrizio , Doss Wahid , Berenguer Marina C.
Published: December 2018

No abstract
Научно-практическая конференция «Клинический случай в нефрологии. 11th REENA ™ CME Course »: обзор ключевых вопросов
Authors: Ivanov D.D.
Published: December 2018

No abstract
Hubungan Kepatuhan Tim Bedah dalam Penerapan Surgery Safety Checklist dengan Infeksi Luka Operasi dan Lama Rawat Inap pada Pasien Seksio Sesarea di Rumah Sakit Umum Daerah Kabupaten Barru
Authors: Amiruddin Amiruddin , Emilia Ova , Prawitasari Shinta , Prawirodihardjo Leo
Published: December 2018

Background: Surgical Patient Safety is essential to be carried out in operating theatre to prevent mortality and surgical complication. Patient safety is the basic principal in medical care and a major component of medical care management in hospital (WHO, 2009).Objective: To investigate association between SSC implementation among surgical team, surgical site infection and duration of hospital stay.Method: This is an analytical cross sectional study. Population of this study was women who underwent cesarean section with live birth in Barru general hospital during 1 December 2016-30 April 2017. This study was carried out in Barru general hospital, 137 samples met inclusion and exclusion criteria. Data was obtained from medical records. Maternal outcome were duration of hospital stay, surgical site infection, and maternal mortality. Besides, this study also assesed knowledge and compliance of surgical team in implementation of SSC. The result of this study was analysed with computer statisctics analysis program.Result adn Discussion: One-hundred thirty seven patients met study criteria. Compliance of surgery team in SSC was 64%,. SSC was not implemented precisely in 36% patients (49 patients). There is no significant association between surgical team compliance with surgical site infection in cesarean section patients (p=0.078). A significant association was found between surgical team compliance with duration of hospital stay (p=0.006).Conclusion: The surgical team compliance in implementation of SSC was not yet optimal. An intensive socialization is needed to improve compliance of team in order that SSC implementation run promptly. This was part of efforts to reduce post operative complication and shorten hospital stay.Keywords: SSC, cesarean section, compliance, infection, duration of hospital stay
Private Sector Development in Kuwait: A Product Space Approach
Authors: Chemingui, PhD Mohammed , Jabsheh, PhD Faten Al , Faki Kais
Published: December 2018

The advent of oil in the GCC countries has led their governments to assume an ever-increasing role in the economy and to build comprehensive welfare states, based largely on the provision of employment in the public sector and the generous supply of social services and heavily subsidized utilities, to their citizens. Moreover, an intricate web of regulatory and restrictive rules and regulations has come into existence over time, resulting in a private sector that is not competitive, is not outward-looking and is generally rent-seeking. The aim of this paper is to investigate the challenges that are preventing Kuwait from succeeding in diversifying its economy and developing a competitive private sector and the pre-requisite enabling environment, thereby reducing its dependence on the oil sector. Results of the analysis carried out in this study reveal that developing the role of private sector in the economic transformation of Kuwait could be achieved through a three interconnected strategies: improving the enabling environment for business to free private sector investors from existing regulations and red tape, developing new markets and opportunities through the creation of new investment opportunities, and ensuring competitiveness and integration with the regional and world economies.
Pengaruh Insektisidal Gorden Celup Deltametrin terhadap Kematian Anopheles spp.
Authors: Zulfikar Zulfikar , Kartini Kartini , Sudiarto Dwi , Aditama Wiwit
Published: December 2018

Gorden dimanfaatkan oleh Anopheles spp. sebagai tempat beristirahat sementara setelah menghisap darah manusia di dalam rumah. Tujuan penelitian untuk mengetahui pengaruh gorden yang mengandung berbagai dosis deltametrin terhadap kematian Anopheles spp. Penelitian ini menggunakan Anopheles spp. dewasa dari hasil penangkapan nyamuk di wilayah pesisir Kota Banda Aceh sebanyak 180 ekor dibagi dalam lima kelompok perlakuan dan satu kelompok kontrol untuk 3 kali pengulangan. Pengujian dilakukan dengan teknik bioassay, masing-masing kelompok terdiri dari 10 ekor nyamuk. Kelompok uji diberi perlakuan dalam cone dengan gorden yang telah dipapar dengan deltametrin selama 3 menit. Kemudian dipindahkan ke dalam wadah pemulihan. Kematian dihitung setelah 24 jam. Perlakuan diulangi 3 kali dengan kondisi yang sama dan nyamuk yang berbeda. Hasil penelitian dianalisis dengan uji ANOVA dan analisis probit. Hasil percobaan diperoleh rata-rata kematian Anopheles spp. untuk dosis 12,5mg/m2 adalah 4 ekor, dosis 25mg/m2 adalah 5,3 ekor, dosis 50mg/m2 adalah 6 ekor, dosis 100mg/m2 adalah 6,7 ekor dan dosis 200 mg/m2 adalah 7,3 ekor. Pada analisis ANOVA nilai dapat disimpulkan ada pengaruh kelima dosis deltametrin terhadap kematian nyamuk Anopheles spp. (p-value <0,001). Dari analisis probit diperoleh persamaan garis probit yaitu y = 0,693x + 4,047 sehingga dapat ditentukan bahwa LD50 adalah sebesar 23,71 mg/m2 dan LD80 adalah sebesar 398,11 mg/m2. Dapat disimpulkan bahwa semakin tinggi dosis deltametrin maka semakin tinggi angka kematian nyamuk Anopheles spp.
Risiko Penularan DBD Berdasarkan Maya Index dan Key Container pada Rumah Tangga Kasus dan Kontrol di Kota Bandung
Authors: Prasetyowati Heni , Astuti Endang Puji , Hendri Joni , Fuadzy Hubullah
Published: December 2018

Kasus Demam Berdarah Dengue di Kota Bandung mencapai 3.381 kasus pada tahun 2016.  Masih tingginya kasus DBD menunjukkan upaya pengendalian vektor DBD belum optimal. Setiap penduduk yang tinggal di wilayah ini berisiko tertular DBD. Risiko penularan dan tempat perkembangbiakan potensial Aedes di suatu wilayah dapat dianalisa dengan maya index dan key container. Tujuan dari studi ini adalah menggambarkan maya index dan key container pada rumah tangga kasus dan kontrol di wilayah Kota Bandung. Kajian ini merupakan analisis lanjut dari hasil penelitian “Penentuan Faktor Risiko Sanitasi Rumah Tinggal Pada Kejadian Demam Berdarah Dengue di Kota Bandung”. Kajian ini menganalisa data berupa jumlah rumah yang diperiksa, jumlah rumah yang positif jentik, jumlah kontainer yang diperiksa, jumlah kontainer yang positif jentik serta letak kontainer. Data tersebut dianalisis lebih lanjut untuk menghitung maya index dan mengidentifikasi key container. Berdasarkan indikator risiko tempat perkembangbiakan dan sanitasi lingkungan, nilai Breeding Risk Index (BRI), Hygiene Risk Index (HRI), serta maya index di wilayah Kota Bandung termasuk kategori sedang baik pada rumah tangga kasus maupun kontrol.  Key container yang ditemukan di rumah tangga kasus dan kontrol adalah dispenser, bak mandi dan ember.
Tarım Toplumları ve Avcı-savaşçı Toplumların Mitlerine Dünya Tasavvuru Bağlamınd
Authors: AKGÖL Ahmet
Published: December 2018

Bu çalışmada çeşitli yaşayış sitillerine sahip toplumların mitleri dünya tasavvuru bağlamında karşılaştırmalı olarak incelenmiş ve mitler arasındaki ortaklıklar ve farklılıkların nedenleri tespit edilmiştir. Ortaklıkları ve farklılıkları daha net görebilmek amacıyla bu çalışmada, mitleri dünya tasavvuru bağlamında incelemek uygun görülmüştür.
Çalışmanın amacı doğrultusunda çeşitli toplumların mitleri dünya tasavvuru bağlamında okunmuştur. Yapılan okumalar sonucunda mitleri okunan toplumlar tarım toplumları ve avcı-savaşçı toplumlar şeklinde ikiye ayrılmıştır. Toplumların mitleri yer, gök, yeraltı, ay, güneş, dünya direği ve varlıkların cinsiyeti başlıkları altında karşılaştırmalı olarak incelenmiştir. İnceleme kısmından elde edilen verilere göre avcı ve savaşçı toplumlarda üç kozmik kuşaktan oluşan dünya tasavvurunun en önemli ortak nokta olduğu tespit edilmiştir. Daha sonra varlıklara bir cinsiyet atfedilmesi ve ayrıca üç kuşağı bir arada tutan bir direğin varlığı diğer en önemli ortak noktalar olarak görülmüştür. Mitler arasındaki farklı noktaların ise ortak noktaların kılık değiştirmiş halleri olduğu tespit edilmiştir. Daha sonra elde edilen verilere göre ortaklıkların ve farklılıkların sebepleri tartışılmıştır. Tartışma sonucunda ortaklıkların sebebi Adolf Bastian’ın Birincil Fikirler, farklılıklar ise Bastian’ın Etnik Fikirler teorisine dayandırılmıştır.
Daniel Defoe'nun "Robinson Crusoe" ve Michel Tournier'nin "Cuma ya da Pasifik Ar
Authors: Bölükmeşe Engin
Published: December 2018

Metinlerarası ilişkiler kavramı, her metnin başka metinlerin birleşmesinden oluştuğu ve bu bağlamdan tüm metinlerin birbiriyle bir şekilde bağlantılı olduğu ilkesine dayanmaktadır. Gérard Genette metinler arasındaki her türlü ilişkiyi metinselaşkınlık olarak tanımlamıştır. Metinselaşkınlık türlerinden biri olan anametinsellik, anametin ve onun öncülü olan bir altmetin arasındaki her türlü bağlantıyı ifade eder. Bu çalışmada altmetin özelliği taşıyan Daniel Defoe’nun “Robinson Crusoe” ve anametin özelliği taşıyan Michel Tournier’in “Cuma ya da Pasifik Arafı” eserleri arasında ortaya çıkan metinselaşkınlık ilişkisinin neden, nasıl ve hangi açılardan meydana geldiğinin belirlenmesini amaçlayan bir inceleme yapılmıştır. Çalışmanın sonucunda altmetinle anametin arasında özellikle Gérard Genette’nin belirlediği, zamansal, uzamsal, anlatısal ve değersel dönüşümlerin izleri açıkça belirlenmiştir.
Edebiyat Öğretiminde Muhafazakâr Kanon
Authors: ÇELİK Tuğba
Published: December 2018

Edebiyatta kanon, otoritelerin belirlediği ölçülerdeki yazar ve şairlerin bir arada anılması ve onlara benzeme koşuluyla başkalarının da bu kümeye alınmasıyla oluşur. Edebiyat öğretiminde kanon, toplumun edebiyat algısının politik bir süzgeçten geçerek oluşmasına yol açar. Bu çalışmanın amacı Türkiye’de oluşturulan dil ve edebiyat dersi öğretim programlarında en sık hangi yazar ve şairlere yer verildiğini araştırmak; bu şair ve yazarlardan bir kanon oluşturulup oluşturulmadığını ortaya koymaktır. Bu çalışmada analitik yaklaşımlardan veri çözümleme yöntemi kullanılmıştır. Buna göre Cumhuriyet’ten sonra Türkiye’deki dil ve edebiyat dersi öğretim programları incelenmiştir; çünkü 1950 öncesindeki öğretim programlarında yazar-şair adı bulunmamaktadır. 1950 itibariyle dil ve edebiyat dersi öğretim programlarında politik ve sanatsal bakımdan yenilikten değil gelenekten yana olan, muhafazakâr yazar ve şairlerin daha çok anıldığı bulgulanmıştır. Çalışmanın sonunda Türkiye’deki dil ve edebiyat dersi öğretim programlarında adı en sık geçen sanatçıların sırasıyla Yahya Kemal Beyatlı (20), Mehmet Akif Ersoy (17) ve Necip Fazıl Kısakürek (16) Ahmet Hamdi Tanpınar (15), Ahmet Haşim (15), Namık Kemal (13), Yunus Emre (11) ve Peyami Safa (10) olduğu görülmüştür. Anılan yazar ve şairler sanatsal ve politik duruş bakımından muhafazakâr bir çizgidedirler ya da Cumhuriyet öncesi dönemine ait sanatçılardır.
Thermodynamic and kinetics analysis of the sulfur-fixed roasting of antimony sulfide using ZnO as sulfur-fixing agent
Authors: Ouyang Z. , Chen Y.F. , Tian S.Y. , Xiao L. , Tang C.B. , Hu Y.J. , Xia Z.M. , Chen Y.M. , Ye L.G.
Published: December 2018

Currently, the commercial antimony metallurgy is mainly based on pyrometallurgical processes and oxidative volatilization of Sb2S3 is an essential step. This step includes the problems of high energy consumption and low concentration of SO2 pollution. Aiming at these problems, we present a new method of sulfur-fixing roasting of antimony sulfide. This method uses ZnO as a sulfur-fixing agent, and roasting with Sb2S3 was carried out at 673 K~1073 K to produce Sb2O3 and ZnS. By calculating the thermodynamics of the reactions, we can conclude that the Gibbs Free Energy Change (?G?) of roasting reaction is below -60 kJ/mol and the predominance areas of Sb2O3 and ZnS are wide and right shifting with the temperature increase, which all indicates that this method is theoretically feasible. The reacted products between Sb2S3 and ZnO indicated that the reaction began at 773 K and finished approximately at 973K. We used the Ozawa-Flynn-Wall, Kissinger and Coats-Redfern method to calculate the kinetics of the roasting reaction. The conclusion is as follows: The average values of apparent activation energy (E) and natural logarithmic frequency factor (lnA) calculated by Ozawa-Flynn-Wall, Kissinger and Coats-Redfern were 189.72 kJ?mol-1 and 35.29 s-1, respectively. The mechanism of this reaction was phase boundary reaction model. The kinetic equation is shown as follow, where ? represents reaction fraction: 1-(1-?)1/3 = 2.12 x1015 exp(-1.90x105/RT) t.
APROXIMAÇÃO DA HISTÓRIA DA MATEMÁTICA PRESENTE NOS LIVROS DIDÁTICOS COM A ESCRITA HISTORIOGRÁFICA TRADICIONAL E ATUALIZADA
Authors: Wagner Soares Oliveira Francisco , Brito Martins Eugeniano , Albuquerque Suziê Maria de , Costa Pereira Ana Carolina
Published: December 2018

A história da matemática como campo de investigação cientifica tem possibilitado, por meio da observação e análise em tratados históricos que carregam em seu conteúdo e contexto uma gama de informações, a produção de narrativas historiográficas das quais são elencados desdobramentos para o ensino. Tal fato tem ocorrido a partir do pressuposto de que a incorporação de elementos da história em sala pode fornecer subsídios ao processo de ensino e aprendizagem. Visto isso, mediante a proximidade com a educação básica, em especial com o ensino médio, desenvolveu-se esse estudo na tentativa de identificar a aproximação das escritas baseadas na história da matemática presentes em livros didáticos do ensino médio com as vertentes historiográficas tradicional e atualizada. Nessa perspectiva, a pesquisa ora realizada foi de cunho qualitativa documental com uma contribuição bibliográfica. Verificou-se nesse estudo que os textos, em que informações da história são elucidadas, possuem características que condizem com a vertente historiográfica tradicional. Em nenhuma das alusões feitas à história foi possível observar um domínio de características que a indicasse como próxima a uma escrita da história nos moldes da vertente atualizada.
REPRESENTAÇÕES MENTAIS UTILIZADAS POR ALUNOS DO ENSINO FUNDAMENTAL NO ESTUDO DO SISTEMA RESPIRATÓRIO HUMANO
Authors: Rodrigues da Silva Tiago , Rodrigues da Silva Bruna
Published: December 2018

O artigo tem como objetivo identificar e analisar os tipos de representações mentais, com base na Teoria dos Modelos Mentais de Johnson-Laird, utilizadas por alunos do ensino fundamental para explicar o sistema respiratório humano. A abordagem foi quali-quantitativa, sendo caracterizada por um estudo descritivo e exploratório. As representações estabelecidas pelos alunos foram categorizadas em proposicionais, imagem e modelo mental. Participaram da pesquisa 31 alunos no 8º ano do ensino fundamental de uma escola pública de Timon/MA. As análises ocorrem através das representações pictóricas estabelecidas pelos alunos antes e após as aulas teóricas e expositivas sobre o sistema corpóreo estudado. Com os conhecimentos prévios, foi verificado que os alunos elaboraram suas representações mentais, nas categorias proposicionais (34%), imagem mental (54%) e modelo mental (12%). Após a organização dos conhecimentos, os alunos demonstraram maior capacidade em estabelecer modelos mentais (69%) e imagem mental (23%), ocorrendo uma diminuição de proposicionais (8%). Com os resultados obtidos foi identificado que, com as aulas teóricas e expositivas os alunos reconstruíram suas representações mentais com a aquisição de conhecimentos científicos. Torna-se possível concluir que ocorreu uma evolução na compreensão dos alunos e de suas representações mentais sobre o sistema respiratório.
EDUCAÇÃO AMBIENTAL E ENSINO DE CIÊNCIAS: CONTRIBUIÇÕES DE UMA AULA DE CAMPO
Authors: Silva de Assis Ana Flávia , Pedrotti Mansilla Débora Eriléia
Published: December 2018

A Política Nacional de Educação Ambiental regulamenta a necessidade de contemplar a Educação Ambiental em todos os níveis e modalidades de ensino, sem delimitá-la como disciplina específica do currículo. A presente pesquisa teve como objetivo identificar as concepções de ambiente desenvolvidas em uma aula de campo com estudantes do ensino médio de uma Escola Estadual em Tempo Integral no município de Rondonópolis, MT. O percurso metodológico se deu através de visita prévia ao local de estudo, aplicação do questionário pré-aula de campo, do roteiro para roda de conversa, vivência em campo e aplicação do questionário pós-aula de campo. Os resultados do questionário inicial e da roda de conversa evidenciam que os estudantes não têm clareza do que entendem por Educação Ambiental, sendo as Concepções de Natureza e Lugar em que se vive as mais frequentes. Através dos relatos durante a aula de campo e do questionário foi possível perceber Concepções mais abrangentes sobre o ambiente se comparado aos resultados obtidos inicialmente. Pode-se concluir que durante a aula de campo, fluíram sentimentos de bem estar, amizade, solidariedade, partilha e respeito, que desencadearam em aprendizados significativos dos conceitos científicos através da vivência em ambiente natural.
O PAPEL DA INTERNACIONALIZAÇÃO ACADÊMICA NA PÓS-GRADUAÇÃO BRASILEIRA
Authors: Maris Wolff da Silva Stella , Rosa Chitolina Maria , Rocha Neto Ivan
Published: December 2018

O artigo pretende analisar a criação, institucionalização e expansão da pós-graduação brasileira a partir da promulgação da Lei de Diretrizes e Bases da Educação Nacional (LDB) e da reforma do ensino superior. Igualmente, discorrerá a respeito dos esforços que as Instituições de Ensino Superior (IES) têm envidado na busca de sua internacionalização acadêmica. Durante a pesquisa, foram levantadas publicações referentes à LDB, Reforma Universitária, e internacionalização da pós-graduação brasileira com as seguintes fases de seleção: 1- Trabalho aleatório na internet para a identificação de informações científicas da área da educação; 2- Cruzamento de palavras-chave, por exemplo, reforma universitária; internacionalização da educação superior; internacionalização e globalização; 3- Identificação de periódicos científicos cujo conteúdo enunciasse a internacionalização da pós-graduação stricto sensu brasileira. A proposta da pesquisa, após a seleção das publicações, foi a de compilar e dar-lhes coesão no empenho de qualificar a pós-graduação diante da era atual.
TECNOLOGIAS DA INFORMAÇÃO E COMUNICAÇÃO E AS METODOLOGIAS ATIVAS: ELEMENTOS PARA O TRABALHO DOCENTE NO ENSINO SUPERIOR
Authors: Carvalho Coletto Priscila Miranda de , Battini Okçana , Monteiro Edenar
Published: December 2018

A utilização da Tecnologias Digitais de Informação e Comunicação (TDICs) e das metodologias ativas no espaço universitário apontam para uma nova forma de estabelecer o trabalho e papel dos professores e alunos no processo de ensino aprendizagem. Nesse sentido, esse artigo traz os resultados de uma pesquisa que teve como objetivo compreender a percepção dos docentes do curso de Enfermagem sobre a utilização das TDICs como elementos mediadores da aprendizagem. Trata-se de uma pesquisa de caráter qualitativo realizada por meio estudo de caso com 6 professores do curso de Enfermagem de uma universidade privada do estado de Goiás. A incorporação das ferramentas tecnológica tende a uma prática pedagógica mais enriquecedora, potencializando a interação e integração bem como a capacidade de compreensão dos conhecimentos, por parte de professores e alunos. Na área de Enfermagem, grandes esforços têm sido realizados com a finalidade de extrair maiores benefícios da utilização das TDICs para obter e/ou garantir um grau maior de qualidade no Ensino. Diante disso permitiu apontar que o ensino de enfermagem mediado pelo uso das TDICs configura-se um desafio exigindo dos alunos, docentes e instituições de ensino superior mudanças na postura frente ao processo educacional.
A EDUCAÇÃO INTEGRAL NO BRASIL: UMA ANÁLISE HISTÓRICO-SOCIOLÓGICA
Authors: Dutra Thiago , Moll Jaqueline
Published: December 2018

A perspectiva contemporânea de educação integral é um direito do cidadão brasileiro respaldado por diferentes marcos legais, concebendo o ser humano em suas múltiplas dimensões e problematizando as finalidades e metodologias aplicadas no sistema atual, se torna uma possibilidade para se superar a crise educacional da atualidade. O Brasil historicamente teve pouca preocupação com a educação dos cidadãos, mas nas experiências que tivemos podemos analisar algumas concepções que se aproximavam da educação integral enquanto outras eram opostas aos princípios que essa defende. A metodologia utilizada vem da história cultural, onde a partir das contribuições de autores como Peter Burke e Jacques Le Goff buscou-se recortes de longa duração visando a construção de um processo de bricolagem, formando ‘uma’ história da educação integral no Brasil através de autores que tratam do tema.  Essa disputa de perspectivas acirra-se, nos dias atuais, nas disputas de projetos de governo na área da educação.
City in Modern Cultural Criticism: Lewis Mumford and István Hajnal
Authors: Kovács Gábor
Published: December 2018

The critique of the city is an almost obligatory cliché of the 20thcentury cultural criticism. This paper offers a parallel critical analysis of the conceptions of American ecologist Lewis Mumford and Hungarian historian István Hajnal. They were contemporaries, and their approaches had been inspired by interwar cultural criticism. Mumford did not hate the city: it was, for him, the engine of history, a reservoir of cultural creativeness. The theory of Hajnal, from many aspects, runs parallel with Mumford’s – moreover, the Hungarian historian gives a detailed theory on the types of European city. What connects them is an ecological approach.
The meaning and development of the Hebrew scalar modifierkexol
Authors: Shefer Hagit
Published: December 2018

The purpose of this paper is twofold; first, it aims to explore the variety of interpretations of the partially schematic Hebrew constructionkexolas inkexol she’ratsiti(‘as much as I wanted’) within the framework of construction grammar; second, it aims to account for this variety through a demonstration of the interrelation between the grammaticalization of the construction and the process of (inter)subjectification or speech-act orientation. The analysis will show that this interrelation has resulted in considerable internal variation in meaning and function in the present day. Corpus findings reveal that initiallykexolfunctioned as a compound consisting of a preposition and a universal quantifier to denote a relation of similarity and comparison. As a result of speaker orientation, the construction has come to exhibit a higher degree of grammaticality in its function as a scalar modifier. Additional schematic and procedural meanings which developed later seem to be the result of hearer-orientation and discourse-orientation tendencies all subsumed under the cover term speech-act orientation
Time frame as a determinant of accessibility of anaphoric demonstratives in Classical Arabic
Authors: Jarbou Samer Omar
Published: December 2018

The aim of this paper is to investigate the determinants for choosing nominal anaphoric demonstratives in Classical Arabic (CA) by examining their usage in a corpus of CA texts. The study makes use of Ariel’s (1990; 2001) concept of ‘unity’ as a theoretical framework from which to study the relationship between an anaphoric demonstrative, its antecedent and their shared referent. This study builds on Jarbou and Migdady’s (2012) findings that ‘anaphoric distance’ (Ariel, 1990; 2001) has not been found to be a primary determinant of cognitive accessibility concerning the use of anaphoric demonstratives in CA. The results of this study show that the choice of proximal/distal anaphoric demonstratives in CA depends primarily on the ‘time frame’ of the referent. Anaphoric demonstratives are temporally anchored in the present time of interaction; if a referent existed within a past time frame or is expected to exist within a future time frame (in relation to the interlocutors’ present time), that referent has low accessibility because of non-sharedness of time frame; if a referent existed or is experienced within a present time frame, it has high accessibility due to sharedness of time frame. Temporal distance replaces physical distance as a determinant of accessibility. In the corpus, proximal anaphoric demonstratives have been used in contexts of high accessibility while distal anaphors have been used in those of low accessibility. Findings of this study contribute to the dynamic view of demonstratives that textual/physical distance is not the primary or sole determinant of accessibility concerning demonstratives.
New Composition Concept for Keroncong Music in the Oboe Concerto with Keroncong and Orchestra
Authors: Sanjaya Singgih
Published: December 2018

this research aims to design a new concept in keroncong music creation with an explorative method. Keroncong is one kind of entertainment musics in indonesia that has a long existece and evolved up to today. Keroncong music is a musical mixture of a western diatonic music with Javanese gamelan music. the term of keroncong comes from the sound “...crong crong crong...” on the ukulele instrument that played rasquardo. an instrumentation music consists of: vocals, violin, flute, cak, cuk, cello, guitar, and bass. during this moment, keroncong is basically just served as a vocal accompaniment music. this becomes a driving force for the author to compose a special composition for keroncong music solo instrument. there is a new concept used in the arranging of this composition, as follows. this composition is designing a concerto, which is a type of the instrumental musics with a western diatonic instrument on the part-one of the solo oboe and an English horn in part-two, with keroncong music and orchestra. the conclusion of these designs are as follows. Keroncong music will be able to stand on its own as an instrumental music.
Tiga Gaya Tari Rantak Kudo Berpotensi Sebagai Sajian Pariwisata Di Kawasan Mandeh Dan Sekitarnya
Authors: Adnan Nerosti -
Published: December 2018

This article is part of the research (2017) to analyze the style of Pesisir Selatan dance in textual and contextual. The study focuses on the style of dance Rantak Kudo from Nagari Painan Timur, Laban, and Bayang. Textual analysis includes (a) Attitude of the body; (b) Transition type of motion; (c) the dimensions of motion; (d) Active moving parts of the body; And (e) Action and effort. Contextual analysis includes the geographical areas of dance, customs, and community life structures. Descriptive evaluative method by comparing the three areas of dance development, namely Rantak Kudo dance of Talaok (Bayang), Rantak Kudo dance of Painan Timur, and Rantak Kudo dance of Laban. The discovery found that Rantak Kudo dance of Talaok  there is a tendency to make a humble movement to the earth, jerking feet rigidly to the ground closely related to the livelihood of the dominant community farming both fields and fields. Rantak Kudo dance of Painan Timur is more varied with patterned motion arrangement leads to artistic, expressing patterns of life and ways of thinking of a developing society. Rantak Kudo dance of Laban, with its close influence of the dance development area of the coast as well as the friendly and intimate style and attitudes of the people, is highly visible in the flexible or non-rigid motion style.
Diagnostic and prognostic potential of non-invasive assessment of cerebral blood flow autoregulation
Authors: Semenyutin V. B. , Aliev V. A. , Bersnev V. P. , Patzak A. . , Panuntsev G. K. , Nikiforova A. A. , Ramazanov Sh. Sh. , Pechiborsch D. A. , Iblyaminov V. B. , Asaturyan G. A. , Dudanov I. P. , Pavlov O. A.
Published: December 2018

Purpose. To study the potential of non-invasive assessment of cerebral blood flow autoregulation (CA) using cross-spectral analysis of slow dopplerographic patterns. Materials and methods. The study involved 40 healthy volunteers and 228 patients with different neurosurgical pathology: cerebral aneurysm - 50 cases, arteriovenous malformation - 52, traumatic brain injury - 61, communicating hydrocephalus - 24, parasagittal meningioma - 20, stenosis and thrombosis of the carotid arteries - 21. Blood flow velocity (BFV) in middle cerebral arteries was monitored using Multi Dop X (DWL, Germany), systemic blood pressure (BP) - noninvasively with Finapres (Ohmeda 2100 USA) within 4 minutes. CA was assessed by calculating the phase shift (PSM) between spontaneous slow oscillations of BP and BFV within the range of systemic Mayer waves (80-120 mHz) and amplitude of intracranial B-waves of BFV (AB) within the range from 8 to 50 mHz). Results and discussion. CA demonstrated different patterns in neurosurgical patients and varied from normal autoregulation to its complete absence. This indicates the degree of compensation of cerebral hemodynamics in pathological conditions such as intracranial hypertension, vasospasm, traumatic edema, ischemia, abnormal arteriovenous shunting. On the basis of perioperative evaluation of PSM and AB, the predictors of efficacy and outcome have been identified in patients with cerebral aneurysms in an acute period of hemorrhage, severe brain injury, cerebral arteriovenous malformations and communicating hydrocephalus. Conclusions. Analysis of slow-wave dopplerographic patterns of BFV in intracranial cerebral arteries and BP is informative, adequate, safe non-invasive way to assess CA in normal and pathological conditions. Perioperative assessment of these patterns can be used to predict the effectiveness of treatment in patients with different neurosurgical pathology.
Ultrasound Diagnostic compared with angiography of low extremity arteries in the diagnosis of multifocal atherosclerosis
Authors: Naiden T. V. , Bartosh-Zelenaya S. Yu. , Guseva O. A. , Abramov E. A.
Published: December 2018

In clinical practice the combined atherosclerotic lesions of several arterial regions are observed twice often in comparison with the isolated lesions. About 25 % of cases of multifocal stenoses are significant (> 50 %) and demand surgical correction. For the purpose of definition of surgical tactics (staging and sequence of revascularization of each region), and tracking of results of treatment, high-informative, available and, as possible, noninvasive diagnostic methods are necessary. Ultrasonic visualization of the arteries is one of such methods. However, so far an X-ray angiography (AG) remains the conventional method of «the gold standard». The screening part is traditionally assigned to the ultrasonic duplex scanning (USDS). Recently several authors report about a successful application of USDS, in a combination with magnetic resonance imaging and/or computed tomography or independently, as a decisive method before operation. The purpose of the current study was to compare the USDS and AG of low extremity arteries in terms of their sensitivity and specificity in patients with multifocal atherosclerosis (MFA). By means of screening of 565 men at the age of 45-59 years, 64 patients with multifocal lesion of coronary, carotid and low extremity arteries were identified. The degree of stenosis had been defined both by USDS and AG. USDS provided best results compared with angiography which failed in detection of smaller grades of stenoses and abdominal aorta aneurysms. Sensitivity of duplex scanning was 90 vs. 75 % for angiography. Application of functional tests can further extend the possibilities of USDS. Thus, ultrasound assessment may be considered a useful method for detecting different characteristics of multifocal athero-sclerotic lesion and planning surgical tactics.
The disturbances of cerebral microcirculation in severe head injury
Authors: Trofimov A. O. , Kalentyev G. V. , Voennov O. V. , Yuriev M. Yu. , Trofimova S. Yu. , Agarkova D. I.
Published: December 2018

The aim of the literature review was to present modern views on the possible mechanisms of the disturbances of capillary blood flow in severe brain injury (TBI). The critical analysis of the concept of secondary brain damage and possible mechanisms of the disturbances of cerebral microcirculation in TBI are presented. We also discuss modern methodologies for assessing capillary blood flow in patients with brain damage. The attention is focused on the causes of the disturbances of cerebral microcirculation in TBI, as well as in various forms of fat embolism in severe combined TBI. Possibilities of prevention and early correction of damaged capillary blood flow in brain injury, as well as the supposed reasons for the failure of some clinical trials, including the widely known CRASH, are analyzed. It is noted that an integrative approach to the assessment of cerebral microcirculation in conjunction with brain metabolism reflects not just the variability of cerebral blood flow and functional disorders of perfusion and metabolism coupling in traumatic brain injury. It is emphasized that ischemia is not the only cause of post-traumatic disorders of pial circulation. We highlight directions for future research of posttraumatic disturbances of cerebral microcirculation as a leading factor of secondary brain insults. The possibility of pharmacological and non-pharmacological correction of microcirculatory disorders in TBI is outlined.
The clinico-functional heterogeneity of changes in the coronary and cerebral blood circulation with the arterial hypertonia of the I stage
Authors: Stroeva V. S. , Kalev O. F.
Published: December 2018

Purpose of this investigation: to determine the early signs of the typological disturbances of coronary and cerebral blood circulation with the arterial hypertonia of the I stage. Materials and the methods. Is carried out a study of cardio-cerebrovascular system in 147 men in the age of 30-59 years with the arterial hypertonia of the I stage, control group they composed 37 clinically healthy men at the age from 29 to 42 years. Results and their consideration. Substantial changes in the coronary and cerebral blood flow with the I stage of arterial hypertonia to the development of the clinical manifestations of the defeat of the vessels of heart and brain are revealed. Is carried out daily monitoring arterial pressure and electrocardiogram, rhythmocardiography, bicycle ergometry, echocardiography, transcranial dopplerography, ultrasonic diagnostics of the main arteries of head and neck. Statistical processing of the results of a study is carried out by the standard methods within the framework of software Statistica for Windows, version 6 and recommended in the management on the biomedical statistics. Obtained by us data give grounds for expanding the criteria, which characterize the defeat of the target organs at the early stage arterial hypertonia. To these criteria we carried the clinical signs of the initial manifestations of the insufficiency of the blood supply of brain and discirculatory encephalopathy of the I stage, and also painless ischemia of the myocardium in the absence of stenocardia and its equivalents, presence of the minimum signs of the disturbance extra and intracranial blood flow (high-speed indices and the asymmetry of blood flow, the index of cerebrovascular reactivity and the presence of microembolic signals). Conclusions. The clinico-functional heterogeneity of changes in the coronary and cerebral blood circulation with the arterial hypertonia of the I stage requires the revision of the standards of the inspection of patients with the development of the increased numbers of arterial pressure, and also start of the new criteria of the early defeat of heart and brain in clinical recommendations.
Experimental models of restrictive cardiomyopathy
Authors: Galagudza M. M. , Kostareva A. A.
Published: December 2018

Restrictive cardiomyopathy (RCMP) is characterized by the isolated diastolic ventricular dysfunction due to increased myocardial stiffness. Animal models of RCMP include the models of acquired and hereditary RCMP as well as the models in large animals. Acquired RCMP is observed in exogenous iron overload, radiation-induced myocardial fibrosis, eosinophilic myocarditis, systemic sclerosis, and amyloidosis. Genetic models of RCMP mimic clinical scenarios of hereditary hemochromatosis and sarcomeric protein mutations. A new approach to modeling RCMP is genetic modification of fruit flies. There are several critical characteristics of successful animal model of RCMP: 1) severe increase in left ventricular end-diastolic pressure in response to volume load; 2) increased ventricular stiffness in the in vitro settings; 3) biatrial enlargement; 4) lack of left ventricular dilation and advanced myocardial hypertrophy.
Skin flap autografting as a method of microcirculation biostimulation in the conditions of normal and impaired innervation
Authors: Ivanov A. N. , Shutrov I. E. , Norkin I. A.
Published: December 2018

The purpose of the study. The estimation of biostimulating effect of skin flap autografting (SFA) on microcirculation in white rats in the condition of normal and impaired innervation. Materials and methods. The experiments were conducted on 5 groups of white rats: two comprison groups - the animals exposed to sciatic nerve neurorhaphy in the acute and delayed periods, and three experimental - animals with SFA in interscapular region without sciatic nerve damaging and together with acute and delayed neurorhaphy respectively. Skin microcirculation was analyzed by Lazer Doppler flowmetry (LDF). Results. After SFA intact animals show inflammatory changes in skin perfusion in the transplantation area that continue up to the 21st day of the experiment. At the same time there is micro bloodflow increase in the foot dorsum skin in the course of the first two weeks of the experiment. In the presence of sciatic nerve damaging there is decrease in skin perfusion and suppression of skin bloodflow neurogenic modulation in the innervation area detected on the 21st day post-neurorhaphy both in acute and delayed period. SFA conducted together with acute and delayed neurorhaphy normalizes skin perfusion in the innervation area of the damaged nerve. This effect is more frank for acute neurorhaphy. Expressed activation of bloodflow endothelial modulation is the attribute of biostimulating effect in delayed neurorhaphy. Conclusion. SFA has significant biostimulating effect on the microcirculatory bloodstream both in normal and impaired innervation. Biostimulating effect of skin flap on microcirculation in the presence of impaired innervation defines the opportunities of its application in the therapy of peripheral nerve damages.
The investigation of infarct-limiting effects of preservation solutions in the rat model of long-time static cold storage of isolated rat heart
Authors: Minasian S. M. , Dmitriev Yu. V. , Galagudza M. M. , Karpov A. A. , Bobrova E. A. , Vlasov T. D.
Published: December 2018

One of the most important aims of modern transplantation is the preservation of the morphofunctional state of donor organs for as long as possible time after removing them from the donor prior to implantation into a patient. To solve this problem, heart preservation solutions are used. However, despite the large number of prescriptions of preservation solutions, the time, limited to six hours, after removing donor heart is still a limiting factor in determining the possibility of implanting heart into a patient. In this study, cardioprotective effects of widely used in clinical practice preservation solution HTK and new Krebs-Henseleit buffer-based preservation solution were studied in the rat model of prolonged static cold storage. It was shown that new Krebs-Henseleit buffer-based preservation solution protected the heart significantly even after an eight-hour global ischemia and has the advantage over Custodiol in the infarct-limiting action.
Ocular blood flow assessment in vascular pathology of the eye
Authors: Kiseleva T. N. , Adzhemian N. A.
Published: December 2018

The review discusses some of the most common methods of ocular microcirculation assessment in vascular lesions of the eye: color and power Doppler imaging, laser Doppler flowmetry, fluorescent and indocyanine green angiography, digital retinal photographs and measurement of retinal vascular caliber, pulsative ocular blood flow analyzer, OCT-angiography. These methods are used in diagnostic of impairment of blood flow in vessels of optic nerve and retina, which also are full informative in early diagnostic of vascular pathology of eye.