bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamics and stability of ψ-fractional pantograph equations with boundary conditions
Authors: Shah Kamal , Vivek D. , Kanagarajan K.
Published: October 2020

This manuscript is devoted to obtain some adequate conditions for existence of at least one solution to fractional pantograph equation (FPE) involving the ψ -fractional derivative. The proposed problem is studied under some boundary conditions. Since stability is an important aspect of the qualitative theory. Therefore, we also discuss the Ulam-Hyers and Ulam-Hyers-Rassias type stabilites for the considered problem. Our results are based on some standard fixed point theorems. For the demonstration of our results, we provide an example.
‎S‎ynchronization ‎of‎ different ‎dimensions‎ ‎fractional-‎order chaotic ‎systems with uncertain‎‎ ‎ parameters ‎and ‎secure ‎communication‎‎‎‎‎
Authors: Vafaei Vajiheh , Kheiri Hossein , Jodayree Akbarfam Aliasghar
Published: October 2020

In ‎this ‎paper, ‎an‎ adaptive ‎modified‎ function projective synchronization (‎AM‎FPS) ‎scheme‎ ‎of ‎different ‎dimensions‎‎ ‎fractional-‎order ‎chaotic systems with ‎fully ‎unknown parameters is ‎presented‎. ‎On the basis of ‎fractional‎ Lyapunov stability ‎theory ‎and adaptive control law‎,‎ a‎ ‎new‎ fractional-order controller ‎and‎ suitable ‎‎‎‎update ‎rules‎ for unknown parameters are ‎designed‎‎ to realize the ‎AMFPS‎ of different ‎fractional-‎order chaotic systems with ‎non-‎identical ‎orders ‎and different dimensions‎‎. ‎‎Theoretical analysis and numerical simulations are given to verify the validity ‎of ‎the proposed ‎method. ‎Additionally, ‎‎‎‎synchronization results ‎are applied to secure communication via ‎‎ ‎modified ‎‎‎‎masking ‎method. Due to the unpredictability of the scale ‎function ‎matrix‎ and ‎using‎ of ‎fractional-‎order ‎systems with different ‎dimensions ‎and ‎u‎nequal‎ ‎orders,‎‎ the proposed scheme has higher ‎security‎‎. The security analysis ‎‎‎demonstrate that the proposed algorithm ‎has ‎a large key space ‎and‎ high sensitivity to encryption keys ‎and it is ‎‎re‎sistance to all kind of ‎‎attacks‎.
Smarandache curves of Bertrand curves pair according to Frenet frame
Authors: Senyurt Suleyman , Çaliskan Abdussamet , Çelik Unzile
Published: October 2020

In this paper, the curvature and the torsion of Smarandache curves obtained by the vectors of the Bertrand partner curve are calculated. These values are expressed depending upon the curve. Besides, we illustrate example with our main results.
On a new class of double integrals involving Gauss's ${}_{2}F_{1}$ hypergeometric function
Authors: Jun Sungtae
Published: October 2020

In this paper, one hundred interesting double integrals involving Gauss's hypergeometric function in the form of four general integrals (twenty five each) have been evaluated in terms of gamma function. More than two hundred special cases have also been given.
Luque Fajardo y la beatificación de san Ignacio de Loyola (1610): campo cultural e imagen autorialLuque Fajardo and the Beatification of Saint Ignatius of Loyola (1610): Cultural Field and Authorial Image
Authors: Aguilera Tania Padilla
Published: October 2020

The Relación de la fiesta que se hizo en Sevilla a la beatificación del glorioso san Ignacio… (Seville, 1610) is an occasional text that clearly reflects the propaganda mechanisms of the time. Luque Fajardo’s description of the festivals and the event held create the appropriate context for a text that bears many similarities with some of its previous models. However, its unifying character is novel and will serve as a model for subsequent religious celebrations. Precisely because of its particular circumstantial character, an approach from the point of view of the sociology of literature is especially pertinent.
La adquisición del lenguaje y noción de la realidad
Authors: Romero Juan Carlos
Published: October 2020

El presente ensayo constituye un intento de relación de tres cuerpos teóricos: el constructivismo radical; la biología de la cognición y la teoría pragmática del lenguaje. El propósito es describir el cómo podría darse la adquisición y/o emergencia de los deísticos de tiempo y espacio, que constituyen los componenetes léxicos básicos de la noción de realidad.  Con este fin se establecen complementariedades y afinidades teóricas que orientan el análisis epistemológico y de la psicología del lenguaje.
¿Cómo Surge el Lenguaje en el Niño?. Los planteamientos de Piaget, Vygotski y Maturana
Authors: Ibañez S. Nolfa
Published: October 2020

El trabajo contrasta el planteamiento de Humberto Maturana con los aspectos básicos de las teorías  de Jean Piaget y L. S. Vygotski sobre el surgimiento del lenguaje. Se discuten las conceptualizaciones propias de cada teoría con respecto a los fundamentos, factores o circunstancias con los que los autores explican la constitución del lenguaje  en el niño. El propósito de esta  contrastación es contribuir a la comprensión de la nueva visión sobre el lenguaje como generador de realidades que aporta la biología del conocimiento de H. Maturana, y que permite cambiar la mirada sobre las condiciones de constitucion en el niño del fenómeno que nos hace propiamente humanos, posibilitando una proyección distinta e innovadora al trabajo pedagógico y psicopedagógico en el área del lenguaje y la comunicación.
Desarrollo de una Identidad con Tendencia a la Vergüenza Una mirada desde la Teoría de E. Erikson y las Interacciones Familiares
Authors: Donoso Niemeyer Tania
Published: October 2020

Este artículo intenta relacionar la resolución de los estadios del desarrollo psicosocial planteados por E. Erikson: Autonomía vs. Vergüenza y Dudae Iniciativa vs. Culpa, con el desarrollo de una identidad saludable o de una identidad con tendencia a la vergüenza (concepto desarrollado por Harper & Hoopes, 1990).En seguida se discuten algunos procesos de interacción familiar que facilitan  la estructuración  de una identidad con tendencia  a la vergüenza en una persona, como también características del funcionamiento familiar que permiten la conformación de una identidad saludable.Finalmente se analiza la función que cumpliría el proceso de diferenciación personal en la posibilidad de cambio desde una identidad con tendencia a la vergüenza  hacia una identidad saludable.
Intervención en un Ministerio
Authors: Foladori Horacio , Sepúlveda Livia
Published: October 2020

El trabajo que se presenta constituye una intervención de análisis institucional realizada en una oficina de un ministerio. Se analiza la demanda, la realización del contrato, la propuesta metodológica y técnica y con minuciosidad el devenir del trabajo grupal según transita por diversos conflictos que atañen a la burocracia. Por último, se señalan algunas conclusiones y recomendaciones a las autoridades.
Memorias para optar al Título de Psicólogo que aportan al trabajo psicoterapéutico. Universidad de Chile 1994 a 1998
Authors: Moncada Arroyo Laura , Costas Moreno Andrés , Olivos Balmaceda Pedro
Published: October 2020

El presente artículo muestra algunos de los resultados encontrados en la revisión de las memorias para optar al título de Psicólogo de los alumnos de Psicología de la Universidad de Chile realizadas entre los años 1994 y 1998 que aportan al quehacer psicoterapéutico, como un intento de sistematización que permita consolidar lo que se investiga.Se presenta aquí la información obtenida en la revisión de las memorias, en relación a las siguientes unidades de análisis: marcos teóricos, tipo de estudio realizado, grupo etáreo y género.Se encontraron creativas propuestas, destacándose algunas intervenciones diseñadas para trabajos individuales y grupales en diferentes líneas psicoterapéuticas. ZSe reseñan y destacan las memorias más originales.
Desarrollo de un modelo de detección, prevención y tratamiento del maltrato infantil a partir del sistema escolar
Authors: Larraín  H. Soledad , Sepúlveda Gabriela
Published: October 2020

Este artículo propone un modelo interdiciplinario de detección. evaluación, prevemción y atención de niños con evidencia o sospecha de maltrato y de su grupo familiar a través del sistema escolar. Sedesarrolló una pauta de detección de maltrato infantil para ser aplicada por profesores y/o orientadores y se desarrollaron talleres para niños , padres y profesores desde un enfoque cognitivo.La evaluación Psicológica del desarrollo afectivo-social de los niños con sospecha de maltrato muestra prodominio de imagenes negativas de sí mismo y del mundo, relaciones interpersonales insatisfactorias, expresión de tristeza, bajo control de impulsos, necesidades básicas insatisfechas, bajo nivel nivel de desarrollo moral y de resolución de problemas interpersonales.Se concluye que siguiendo los pasos establecidos en el modelo propuesto, es posible desarrollar un programa preventivo de maltrato infantil en la comunidad, partiendo desde el sistema escolar , en donde los profesores, previamente capacitados tienen un rol de liderazgo en el trabajo con niños y padres.
Ciudadanía y autocuidado en salud reproductiva y sexual: Un estudio exploratorio en mujeres trabajadoras de los sectores salud y educación
Authors: González Rodriguez Sergio , Arriagada Pincetti Marcela
Published: October 2020

Se relacionan las temáticas de Ciudadanía y Autocuidado en salud reproductiva y sexual  refiriendose un estudio en mujeres  que trabajan en las areas de salud y educación con formación universitaria y técnica. A trvez de un encuadre metodológico cualitativo basado en entrevistas en profundidad se analizan las practicas de autocuidado  en estas areas y se  constatan las carencias determinadas por creencias,  contenidos congnitivos - emocionales y relaciones  proveedor/usuaria que inhiben su fortalecimiento. Consecuentemente, se establecen derechos ciudadanos en el ámbito de la salud reproductiva, los cuales asegurarias mayores niveles de responsabilidad y de autonomia en el autocuidado, reforzando el establecimiento de ciudadanias activas.
Alphas: A Case study in International Institutional Mutual Funds
Authors: Delgado Francisco A , Goldberg Cathy S , Graham Carol M.
Published: October 2020

In this paper we show that not taking into account the fact that fund managers “deviate” from their stated categories biases upward their alphas. When evaluating fund managers most studies compare managers against the S&P 500 regardless of the sectors managers actually invest in. This procedure does not take into account that an important proportion of US stock managers invest in medium and small companies. This neglect biases performance results. In the international stock arena, not only do studies use the incorrect benchmark but they also neglect to take into account the fact that managers deviate from their stated sector. In this paper we not only employ the correct category the managers invest in but we also take into account the fact that managers systematically drift away from their stated category. This drift occurs for approximately half the funds examined and causes the estimated alpha of managers to be on average 45 basis points higher than it should be if we were to undertake the multiple regression that fund drift demands. In addition to using the right benchmarks, adjusting for “drift” in this paper we chose to use as “benchmarks” the ETF’s in each category so as to compare managers not against theoretical constructs, but against an actual investable vehicle in the corresponding category.
Internally Displaced and Refugee Students in Cameroon: Some Pedagogical Proposals
Authors: Safotso Gilbert Tagne
Published: October 2020

For some six years now, Cameroon has been experiencing unprecedented war disturbances. Since 2014, its three northern regions have been undergoing the hardship of Boko Haram ruthless attacks leading to thousands of internally and externally displaced families and hundreds of schools closed down. The Minawao Refugees Camp near Mokolo with over 60 000 inhabitants, mostly Nigerians, somewhat testifies to the gravity of the situation. A similar Camp is located in Gado-Badzere near Garoua-Boulaï in the East Region, populated by Central African Republic refugees. The Zamay Camp is occupied by internally displaced Cameroonian families of the far North Region. The troubles in the South and North-West which started in 2016 considerably increased the number of internally displaced Cameroonians in the neighbouring French-speaking zones of the West and the Littoral Regions. In the refugee camps or in the invaded zones, class sizes have simply become unmanageable with many of them rising from simple to double or triple. Teachers who were trained to teach around 50 to 100 students per class have suddenly found themselves managing 150 - 200 learners in some classes without any preparation. Among the learners of the same class, some have abandoned school for two to three years. Those learners thus need a special pedagogy. This paper aims to propose some pedagogical solutions to such classes.
Does Stock Listing Affect Value Creation and Profitability? Evidence from European Listed and Unlisted Companies
Authors: Intrisano Carmelo , Micheli Anna Paola , Calce Anna Maria
Published: October 2020

In this paper we have studied the issue of whether the stock listing decision impacts firms’ performance and value. In detail, we compared listed and unlisted companies located in countries belonging to the Stoxx Europe 600 in a 3-year time horizon (2015-2017). Companies are grouped in sector in order to ensure a greater comparability of data. As variable representative of performance we used the return on equity while for value creation we chosen the ROE-ke differential. Using the statistical t-test we ascertain the comparability of values. Results of our study demonstrated that unlisted companies have greater profitability and generate higher value than listed peers. In particular, given the significance level at 1% resulting from the t-test for the difference between the means, profitability and value created are higher for unlisted companies compared to the listed especially for the Thecnology, Telecommunication and Industrials sectors.
Chadian Learners’/Users’ Preferred Variety(ies) of English
Authors: Safotso Gilbert Tagne , Tompté Ndoubangar
Published: October 2020

Although French and Arabic are the official languages of Chad, for the past twenty years Chadian learners and users of English have been having a strong interest in the language. Their number in Cameroonian, Nigerian, Ghanaian and Sudanese universities as well as in linguistic centres in N’Djamena testifies to this. It can be said that the petrol boom in the country has really changed the attitudes of Chadians towards English. They see in it the language of opening and opportunities. Given that in most major languages there are accents and variants, and most especially with English the lingua franca of the 21st century, it is important to know those learners’/users’ preferred variety (ies). This paper thus aims to know which variety (ies) of English Chadian learners/users prefer to hear or speak. The data was gathered through a questionnaire administered to 106 university students, 97 secondary school learners, 18 English language teachers and 29 workers of other sectors (N = 250). Results show that most Chadian learners/users prefer American or British English and a good percentage of them favour Ghanaian or Cameroon English.
Democracy in Education between Reality and Aspirations: Palestine as a Model
Authors: Shuibat Mohammad Awad
Published: October 2020

The research aims to study “education democracy " in terms of democratic practices in the educational process, developing a spirit of criticism, plurality of opinions, tolerance towards the opinions of others, respecting the decision of the majority and taking responsibility for the decision. In addition to the relationship between democracy and education, the relationship between democracy and education as a practice, and clarifying the goals of education for democracy, and clarifying areas of democratic awareness, the implications of education for democracy and procedures for developing democratic practices in education and the detection of obstacles to democratic practices in the educational process, and that is in the context of an applied analytical and scientific study based on the researcher's visit to Palestinian educational institutions and his knowledge of their reality, through which the researcher seeks to present what is hoped from the "education democracy" and how should it be applied to reality and what goals should these institutions seek to achieve?
Lost verplichte aanwijzing accountant problemen van beursvennootschappen op?
Authors: Eijkelenboom E.V.A.
Published: October 2020

Lost verplichte aanwijzing accountant problemen van beursvennootschappen op?

Controleplichtig maar geen accountant kunnen vinden. Het overkomt verschillende beursvennootschappen. Minister Hoekstra is daarom voornemens om een verplichte toewijzing van een accountant aan controleplichtige entiteiten wettelijk te verankeren. In deze bijdrage staan de achtergrond en enkele aandachtspunten bij het voornemen van verplichte aanwijzing van de accountant centraal.
Autobiography after Wittgenstein
Authors: Szabados Béla
Published: October 2020

Béla Szabados claims that Wittgenstein in his observations on the roles, functions and possibility of autobiography anticipates the death of the traditional autobiography and points to a way of transforming the genre so as to make it suit our present concerns. The article addresses Wittgenstein’s strategies in his own autobiographical projects. Szabados points out that the eclipse of the traditional autobiography, as described and performed by Wittgenstein, refl ects the exhaustion of cultural forms that previously shored up confessional practices, and this exhaustion can be seen in the changes to the autobiographical form that have occurred since Augustine and Rousseau.
„Literary Theory Two” as a threat to humanities
Authors: Tiupa Walerij Igoriewicz
Published: October 2020

The article is concerned with one of the newest trends in literary studies championed by the journal Translit. The „new poetics” promulgated by the journal, as well as the underlying „pragmatic theory of literature”, signifi es a rejection of the aesthetic focus in writing. In its crusade against the „aesthetic ideology” the journal adopts an extreme form of relativism and adheres to the theory of power struggle between elites as a key driving force of social relationships. The author argues that attachment of a fetish status to writing tools (especially the most fashionable electronic ones), a dismissal of „anthropocentricity” in favour of „posthumanism” by pragmatic theorists, and an aggressive search for „epistemological and political enemies” are the major concerns in the contemporary cultural crisis.
Songverse: a digital musical instrument based on Virtual Reality
Authors: Costa Willams de Lima , Filgueira Daniel , Ananias Luca , Barioni Ricardo , Figueiredo Lucas Silva , Teichrieb Veronica
Published: October 2020

We can define Digital Musical Instruments (DMIs) as hardware-software solutions that are interactive and crafted to output sound according to users' input. DMIs are well known to unleash users' creativity but also to allow different and innovative experiences for the creation process, for example, smoothing the learning curve towards musical concepts such as rhythm and composition. On the other hand, Virtual Reality (VR) allows users to explore spatial interfaces in a natural and limitless way, which shows potential synergy towards the rise of new DMIs. In this paper, we introduce Songverse, an immersive DMI placed in a Virtual Reality scenario that allows users to create music by interacting with an environment designed to resemble the outer space. By adding systems, planets, and satellites to the virtual environment, the user can shape the produced sound through interactions that were extensively tested during the development phase. We then evaluated the instrument with musicians and non-musicians by interviewing and applying the System Usability Scale (SUS) to assess the easiness for people to create music using Songverse. As a result, users reported the use of the DMI as intuitive and easy to use, also highlighting the produced song as enjoyable.
Exploring Non-conventional Sensorimotor Devices in a Virtual Bicycle Simulator
Authors: Almeida Raphael de Souza e , Oliveira Renato Cherullo de , Radetic Daniel , Silva-Calpa Greis Francy M. , Raposo Alberto Barbosa
Published: October 2020

This work presents SimBike, a virtual bicycle simulator that uses non-conventional motor, sensory and sensorimotor devices to provide greater user involvement and comfort. SimBike aims to recreate the activity of riding a bicycle by exploring possibilities of electronic devices, such as making curves with the handlebar or body-weight, pedaling, braking, among others. It also offers feedback commonly expected by the rider, such as wind sensation varying according to speed and the sensation of trepidation on uneven terrain. The simulator was evaluated with 16 users, obtaining positive results regarding user experience, comfort, and immersion. As future work, we propose to improve some features to adapt the simulator for all users, regardless of their weight and height.
The Effects of Environment Uncertainty and Leadership Styles on Organisational Innovativeness
Authors: Strugar Jelača Maja , Milićević Nikola , Bjekić Radmila , Petrov Viktorija
Published: October 2020

The paper aims to better understand the importance of a company’s external environment uncertainty level and the CEO’s leadership style for innovation. Different leadership styles were assessed in the context of a full range leadership theory, namely: transformational (Tfl), transactional (Tsl) and passive leadership (PL). Partial Least Squares-Structural Equation Model was developed, tested and validated to explain the effect of environment uncertainty and leadership style on organisational innovativeness. The hypotheses were tested using responses of managers from 159 medium and large organisations in the Republic of Serbia during 2017. The results suggest that there is a statistically significant relationship between environment uncertainty and organisational innovativeness, while transformational leadership was described as important leadership style that cannot be ignored if organisation wants to improve organisational innovativeness. Influence of transactional leadership was not statistically significant, while passive leadership style was found to have the negative influence on organisational innovativeness. Based on the results of the study, practical implication of creating a more supportive workplace for all types of innovation is emphasised. Encouraging managers to predominantly use proactive leadership, i.e. transformational style, facilitates significant innovative capacity. The effective use of leadership style and its innovativeness in South-eastern European countries is vastly unexplored. Thus, the results of the research fill the literature gap between Western leadership theory and South-eastern European context.
Board Long-Term Orientation, Earnings Management, Disclosure and Risk
Authors: Herrera-Echeverry Hernan , Haar Jerry , Velasquez-Gaviria Daniel , Upadhyay Siddharth
Published: October 2020

Short-term thinking continues to dominate corporate decision making due to the pressure to achieve expected quarterly earnings. As such, strategic goals take a back seat to short-term performance among the prime objectives of CEOs, the board of directors and management teams. Be that as it may, shareholders and stakeholders expect corporate leaders to pay equal attention to the long-term health of the corporate enterprise. An empirical study is conduced to test how long-term oriented board of directors diminish earnings management, increase disclosure and reduce risk. The results show that a long-term board orientation decreases earnings smoothing, stock price synchronicity and downside risk. To study this relationship, we construct a panel data from 2004 to 2015 comprising of 2834 OECD country firms. We conclude that board independence, board expertise and board audit committee activity increase long-term firm orientation. We find that boards with these characteristics are prone to the implementation of executives’ long-term incentives, suggesting that a long-term orientation is beneficial not only to increase firms’ transparency and disclosure but also to reduce firms’ downside risk. Firms with long-term orientation reveal enough information to avoid stock price synchronicity, prevent the use of earnings management to conceal real firm performance and reduce downside risk - all decreasing the chance of financial failure. The results of the study not only nullify the arguments that there is no impact of long-term orientation and long-term incentives but also bolster and enrich the stream of literature that supports these variables’ impact on earnings management, stock price synchronicity and downside risk. Within the context of the international setting of the paper, we have substantiated the external validity of the results across geographies and country-wide regulations.
The Relationship between CO2 Emissions, Industry, Services and Gross Fixed Capital Formation in the Balkan Countries
Authors: Mitić Petar , Kostić Aleksandar , Petrović Evica , Cvetanovic Slobodan
Published: October 2020

The examination of the economy-environment nexus is one of the focal issues in the field of environmental economics. This study examines the causal relationships between carbon dioxide (CO2) emissions, industry, services, and gross fixed capital formation for a panel of Balkan countries over the period 1996-2017. A three-step methodological approach is used, including panel unit root tests, panel cointegration tests, and panel causality tests. The results suggest a strong cointegration between the variables, meaning that all variables have a long-run relationship with CO2 emissions. The results of the panel causality show that there is a short-run bidirectional panel causality running between industry and services, and gross fixed capital formation and services. Moreover, there is a unidirectional causality running from industry and gross fixed capital formation to CO2 emissions, and from industry to gross fixed capital formation. The results of the long-run causal relationships show that estimated coefficients of the error correction terms (ECT) in the case of CO2 emissions, industry and gross fixed capital formation are statistically significant, indicating that these three variables are an important part in the adjustment process as the model diverges from the long-run equilibrium. Balkan countries need to further invest in the modernisation of their technological process, as well as to act following the global policy incentives. Environmental taxes, carbon capture and storage, taking part in emission trading schemes and orientation towards renewable energy sources, should further strengthen Balkan countries in achieving environmentally sound economic growth.
A critical review on nano-food packaging and its applications.
Authors: BHATT Sheelendra M
Published: October 2020

The present manuscript addresses the effect of nanotechnology in various food sectors. Increasedfood functionality, enhanced flavor, reduced delivery of food additives are some of theappealing choices raising plausibility of high health advantages hypothesized in future. At theface of explosion of information, it is important to monitor them in a brief and updated manner.In this manner, new nanomaterials like carbon nanotubes, nano-biopolymers have diverseapplications in food packaging, good food release property with enhanced food safety features.Furthermore, nano-encapsulation of probiotics, nano applications in food processing sector andother related issues, new functional nanomaterials for use in food along with their propertieshave been talked about in this review paper.
Could COVID-19 Cause ‘Biopharming’ to Bloom?
Authors: Hefferon Kathleen , Miller Henry , Miller Henry
Published: October 2020

At an accelerated rate in response to the COVID-19 pandemic, academic and corporate scientists are using genetic engineering techniques to reprogram plants to produce significant concentrations of high-value pharmaceuticals. The concept is not new. Many common medicines, such as certain opiates, the laxative Metamucil, and the anti-cancer drug Taxol, are all purified from plants, and efficacy has been shown for some herbals in Traditional Chinese Medicine. There is great potential for cost-cutting in the process: The energy for product synthesis comes from the sun, and the primary raw materials are water and carbon dioxide. In addition, biopharming offers tremendous flexibility and economy when adjustments in production are necessary. The need for inexpensive, flexible production techniques for COVID-19 therapeutics and vaccines could be a potent stimulus to biopharming research and development.
Challenging the Nurney Procedure by the Roma national community
Authors: Haliti Bajram
Published: October 2020

World War II is considered to be the largest and longest bloody conflict in recent history. It began with the German attack on Poland on September 1, 1939. The war lasted six years and ended with the capitulation of Japan on September 2, 1945. The consequences of the war are still present in many countries today. "German, Italian and Japanese fascists waged a war of conquest with the aim of dividing the world and creating a New Order in which it would have economic, political and military domination, establish a rule of terror and violence and destroy all forms of human freedom, dignity and humanism. Only a few thousand Roma in Germany survived the Holocaust and Nazi concentration camps. Trying to rebuild their lives, after losing so many family members and relatives, and after their property was destroyed or confiscated, they faced enormous difficulties. The health of many was destroyed. Although they have been trying to get compensation for that for years, such requests have been constantly denied Based on established facts, eyewitnesses, witnesses, historical and legal documents, during the Second World War, the crime of genocide against Orthodox Serbs, Jews and Roma of all faiths except Islam was committed. The attempt to exterminate the Roma during the Second World War must not be forgotten. There was no justice for the survivors of the post-Hitler era. It is important to note that the trial in Nuremberg did not mention the genocide of the Roma at all. The Nuremberg trial is basically the punishment of the losers by the winners. This is visible even today because these forces rule the world. Innocent victims, primarily Roma, have not received justice, satisfaction or recognition from the world community. The Roma were further humiliated because they were not given a chance to speak about the few surviving witnesses about the victims and the horrors they survived. The Roma for the Nuremberg International Military Court and the Nuremberg judges simply did not exist, which called into question the legal aspect of the process, which has not been corrected to date. The Roma national community is committed to revising history, to reviewing the work of the Nuremberg tribunal.
The bibliostatistical analysis of the first 25 volumes of a collection of academic papers «Factors in experimental evolution of organisms»
Authors: Kunakh V. A. , Mozhylevska L. P.
Published: October 2020

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Distribution of isonymy index in the territory of Ukraine
Authors: Gorpynchenko M. Yu. , Atramentova L. A.
Published: October 2020

Purpose of the study: to calculate the irrationality index Ir for the population of the region level, to analyze the regularity of distribution of its values in the territories of Ukraine, which differ in geographical conditions and previous history of population formation. Methods. Using total names, isonymy indices for the entire population of Ukraine, individual regions and oblasts are calculated. Results. The Ir index for the whole population of Ukraine is 2,13×10-4. In some regions of Ukraine it has the following meanings: east – 2,69×10-4, south - 2,23×10-4, center - 3,15×10-4, north - 3,40×10-4, west – 2,40×10-4. The Ir frequency distribution map for regional populations shows a gradient of this index rising from the southeast to the northwest of the country. The minimum Ir value is observed in the Crimea (1,61×10-4), the maximum in the Volyn region (7,14×10-4). Conclusions. The Ukrainian population isonymy index is of the same order of magnitude as in other European countries. The territorially dependent variation of the isonymy index is explained in the peculiarities of the history and landscape of the area.

Keywords: population, isonymy, surnames, migration, genetic drift.
The role of siRNAs in genome stability maintaining in the bread wheat introgression lines
Authors: Navalikhina A. G. , Antonyuk M. Z. , Ternovska T. K.
Published: October 2020

Aim. Deviations of the siRNAs levels from the parental ones in the plants with hybrid genomes are associated with the activation of transposable elements (TE). This, in turn, lead to the further genome rearrangements. Introgression lines Triticum aestivum / Amblyopyrum muticum are cytologically stable, however, there are visible signs of genetic and (or) epigenetic restructuring that are still going on. Molecular mechanisms of these processes are the subject of our study. Methods. The levels of siRNAs in the plant lemmas were determined by small RNA-seq. Reads of the small RNA libraries were aligned to the repeats to find siRNA sequences. Results. Introgression lines (ILs) and parental amphidiploid have variable levels of siRNAs regulating MITE and CACTA transposable elements, compared with the parental bread wheat variety. For twelve TE sequences, majority of which are CACTA elements, decrease in the levels of siRNAs in ILs and amphidiploid, compared to the wheat, is statistically significant. Decreased siRNAs levels could lead to the activation of corresponding TE classes. Conclusions. Variation of siRNA levels in ILs and amphidiploid can be the key factor that cause rearrangements in their genomes. These include activation of TEs, changes in DNA methylation patterns, and gene expression variation. Therefore, detected changes in siRNA levels can be the molecular mechanisms of the processes that occur in studied hybrid genomes.

Keywords: siRNA, transposable elements, amphidiploid, introgression lines.
Estimation of NAM-A1 haplotypes effect on the level of quantitative traits and grain protein content in wheat
Authors: Orlovskaya O. A. , Vakula S. I. , Khotyleva L. V. , Kilchevsky A. V.
Published: October 2020

Aim. NAM-A1 gene plays an important role in the regulation of metabolic processes, the remobilization of nutrients from the wheat vegetative organs to grain. The aim of this work is the genotyping of SNP polymorphisms of the NAM-A1 gene in introgression lines derived from the cross of bread wheat varieties with species of genus Triticum, as well as estimation of NAM-A1 haplotypes effect on quantitative traits and grain protein content of the studied genotypes. Methods. NAM-A1 gene polymorphisms were identified using the TaqMan - Real-time PCR. Statistical data analysis was carried out using MS Excel 2007, Statistica 10.0. Results. NAM-A1c haplotype is mainly found in the studied genus Triticum species, NAM-A1d - in bread wheat varieties, and mixed haplotypes - in the introgression wheat lines. Statistically significant associations among NAM-A1 gene haplotypes and productive tillering of plants, the length of the main spike, the number of spikelets in the main spike and the thousand kernel weight were revealed. Conclusions. A significant effect of the NAM-A1 haplotypes was established for the traits «productive tillering» and «thousand kernel weight». The highest thousand kernel weight was reached in plants carrying the haplotype NAM-A1d.

Keywords: T. aestivum L., species of genus Triticum, NAM-A1, SNP, quantitative characters.
Quantitative description of early transcriptional response of plant cells to radiation-induced DNA damage using a Poisson initiation event model
Authors: Litvinov S. V. , Rashydov N. M.
Published: October 2020

Aim. One of the problems that have not lost their relevance is the study of the mechanisms of adaptation of higher plants to the effects of radiation associated with the modification of the DNA repair system in response to radiation. This paper presents a Poisson mathematical model of the radiation-induced early transcriptional response of genes of key enzymes, which catalyze recovery of double-stranded DNA breaks in active plant cells. Methods. We used total X-ray irradiation of a model object – 35-day-old Arabidopsis thaliana (L.) Heynh plants at sublethal doses of 3-21 Gy, total RNA extraction, reverse transcription with random hexanucleotide primers, PCR amplification of the obtained cDNA with primers to target genes, fluorescence gel densitometry of amplified products. Results. A mathematical model of transcriptional response to the genotoxic action of ionizing radiation in a subpopulation of active plant cells based on Poisson distribution, which satisfactorily describes the experimental data obtained, is proposed. Conclusions. To initiate a maximal transcriptional response to DNA damage, one two-strand lesion per chromosome, detected by DNA repair systems, is sufficient, while the absence of double-stranded lesions, or the appearance of more than one double-stranded lesion per chromosome inhibits early transcriptional response of the cell on the action of ionizing radiation. The Poisson model of the initiating event makes it possible to predict the response of subpopulations of active cells of angiosperms to the action of genotoxic factors.

Keywords: ionizing radiation, DNA damage response (DDR), Arabidopsis thaliana, DNA repair, gene transcriptional activity.
Synthesis, characterization and antiradiation properties of the tryptophanates of cobalt (II), manganese (II), copper (II) and zinc
Authors: Shamilov E. N. , Abdullaev A. S. , Farajov M. M. , Shamilli V. E. , Gahramanova Sh. I. , Jalaladdinov F. F.
Published: October 2020

Aim. In order to study the radioprotective activity were were obtained in the tryptophanates of cobalt (II), manganese (II), copper (II) and zinc. Methods. The composition and structure of the complexes were studied by elemental, thermogravimetric analyzes and IR infrared spectroscopy. To determine the presence of the Radioprotective Properties of the Co (II), Mn (II), Cu (II), Zn complexes with tryptophane, a test was conducted for the 30-day survival of irradiated animals. Results. The results of thermogravimetric studies have shown that the final product of the thermal decomposition of all compounds is metal oxide, respectively. The method of IR spectroscopy showed that the ligands in the composition of the metal (II) complexes enter the neutral form and coordinate with the complexing agent through the nitrogen atom. The results of experiments with complexes showed that they have noticeable radioprotective activity. The radioprotective activity of Co (II) complexes with tryptophan is 55%, Mn (II) with tryptophan 50%, Cu (II) with tryptophan 40%, and Zn 30%. They improve the survival and average life expectancy of lethally irradiated mice, not reaching the level of the known cystamine radioprotector, which is 80%. Conclusions. The data obtained by us testify to the prospects of using the complexes of Co (II), Mn (II), Cu (II), Zn with tryptophan for preventive purposes and in order to prevent local radiation injuries.

Keywords: tryptophan-metal complexes, IR spectroscopy, thermogravimetry, complex compounds, radioprotective properties.
Polyploidization of Miscanthus sinensis using dinitroanilines with low phytotoxicity
Authors: Melnychuk O. V. , Ozheredov S. P. , Rakhmetov D. B. , Rakhmetova S. O. , Bayer O. O. , Shysha O. M. , Yemets A. I. , Blume Ya. B.
Published: October 2020

Aim. The aim of the work was to obtain polyploid lines of Miscanthus sinensis with enhanced biomass productivity using new dinitroaniline compounds. Methods. The work was carried out in in vitro conditions. Aseptic M. sinensis shoots were cultured on shoot multiplication medium containing various compounds of dinitroanilines class. Classic dinitroanilines (oryzalin and trifluralin) were used as a control. Results. When aseptic shoots were cultured on medium supplemented with oryzalin and trifluralin at concentration 10 mM, survival rate of explants was between 23.52 and 44.40%. However, when the medium was supplemented with tested dinitroanilines at the same concentration, survival rate of explants was in the range of 95.0–96.5%. Conclusions. Possibility of new compounds of dinitroanilines class utilization for M. sinensis polyploidization has been studied. In terms of explants survival rate, application of new compounds of dinitroanilines class appeared to be significantly effective than application of classic dinitroanilines.

Keywords: dinitroanilines, in vitro, polyploidization, Miscanthus sinensis.
Genetic transformation of new perspective winter wheat genotypes in vitro
Authors: Slivka L. V. , Dubrovna O. V.
Published: October 2020

Aim. Optimization of conditions for genetic transformation of new perspective winter wheat genotypes and production of transgenic plants. Methods. Agrobacterium-mediated transformation in vitro culture using callus cultures. Results. The influence of the optical density of cells of agrobacterial suspension, the concentration of the antibiotic cefotaxime, the duration of coculture on the frequency of obtaining kanamycin-resistant regenerants of new winter wheat genotypes by genetic transformation of callus cultures were investigated. By Agrobacterium-mediated transformation of morphogenic calluses of new perspective winter wheat genotypes were obtained plant-regenerants in the genome of which revealed the complete incorporation of a genetic construct containing oat and nptII transgenes. Conclusions. Agrobacterium-mediated transformation of callus cultures of new perspective winter wheat genotypes was optimized, and transgenic plants with the target gene of ornithine-δ-aminotransferase were obtained.

Keywords: Triticum aestivum, Agrobacterium-mediated transformation, callus cultures, ornithine-δ-aminotransferase gene.
The content of phenolic compounds and flavonoids in in vitro plants and tissue culture of Deschampsia antarctica E. Desv.
Authors: Twardovska M. O. , Konvalyuk I. I. , Lystvan K. V. , Andreev I. O. , Kunakh V. A.
Published: October 2020

Aim. The aim of the study was a comparative assessment of total phenolic content and total flavonoid content in in vitro plants, regenerated plants, plants grown in a growth chamber, and tissue culture of several genotypes of Deschampsia antarctica. Methods. In vitro culture, Folin-Ciocalteu method, spectrophotometry, high-performance liquid chromatography. Results. The total content of phenolic compounds and total flavonoid content was determined in the samples of three D. antarctica genotypes: G/D12-2a (2n=26), DAR12 (2n=26+0–3B) and Y66 (2n=36–39). The content of these biologically active compounds was the highest in in vitro plants and it was higher than in plants grown in a growth chamber. The highest content of BAC was found in DAR12 in vitro plants (16.50 mg of ferulic acid equivalent and 21.26 mg of rutin equivalent per g of dry weight, respectively). The regenerated plants did not differ significantly in the content of BAC from the original in vitro plants. In tissue culture, the content of BAC was lesser. One- and two-year-old tissue cultures did not differ significantly in the content of phenolic compounds and flavonoids. Conclusions. The relatively high content of phenolic compounds and flavonoids in in vitro plants and in regenerated plants indicates that in vitro cultivated D. antarctica plants can be a promising raw material for production of valuable BACs. Keywords: Deschampsia antarctica E. Desv., in vitro plants, plant tissue culture, phenolic compounds, flavonoids.
Obtaining of the recombinant Rhil7-Cbd fusion protein
Authors: Usenko M. O. , Gorbatiuk O. B. , Okunev O. V. , Irodov D. M. , Koval’chuk M. V. , Kordium V. A.
Published: October 2020

Aim. The purpose was to obtain the recombinant fusion protein based on the human interleukin-7 (rhIL7) and cellulose binding domain (CBD). Methods. The DNA sequences encoding rhIL-7 and CBD were subcloned into the pET24a(+). Vector containing the 6His-tag sequence for further chromatographic purification of the target protein. The cells of E. coli strain BL21(DE3) were transformed with pET24-rhIL7-CBD plasmid vector. Protein synthesis was induced in clones by IPTG and by autoinduction. Results. An expression cassette of rhIL7-CBD protein has been designed. Producers of rhIL7-CBD protein were obtained. It was shown that the autoinduction protocol provides protein synthesis in E. coli (but IPTG induction doesn’t). Protein was obtained in the cytoplasmic fraction in form of inclusion bodies. In vitro method of purification of rhIL7-CBD from inclusion bodies has been worked out. Conclusions. The obtained rhIL7-CBD protein can be used for the microcrystalline cellulose immunosorbent construction for the purification of the specific polyclonal IL-7 antibodies and also for qualitative and quantitative analysis of IL-7 receptors.

Keywords: IL-7, CBD, inclusion bodies, renaturation.
The inhibitory effect of KN-93 and KN-62 as a result of CaM-directed blocking animal CaMK2 and plant CDPK activation
Authors: Novozhylov D. O. , Karpov P. A. , Samofalova D. O. , Popitak M. A. , Blume Ya. B.
Published: October 2020

Aim. The goal of the study was determine whether, from a molecular point of view, inhibitors KN-93 and KN-62 are capable to disrupt the functioning of plant homologs of CaMK2 and being used as tools for the experimental study of Ca2+-dependent phosphorylation in higher plants. Methods. Selected calmodulin 1 H.sapiens reference structure and reconstructed spatial structure of calcium-binding domain of CPK1 A.thaliana. We have conducted the molecular docking of calmodulin-mediated inhibitors to CaMK2: KN-93 and KN-62 for CALM1 H. sapiens and calcium-binding domain of CPK1 A. thaliana with full ligand mobility and static amino acid residues with the use of CCDC GOLD Suite. Results. We have established the presence of spatially homologous structures within CALM1 and CPK1 that might be the binding sites for KN-93 and KN-62. Performing the molecular docking we have shown the utility of those pockets from the point of binding energy for KN-93 and KN-62. We have conducted comparative analysis basing on the results of the CCDC GOLD Suite score functions (GoldScore and ASPScore). Conclusions. It has been shown that the inhibitors of animal CaMK2 - KN93 and KN62 are capable of interacting with the site of the CaM-like domain of the plant protein kinase CPK1 homologous to the similar site of animal calmodulin, which may impair its functionality.

Keywords: CaMK2, CDPK, CPK1, protein kinases, molecular docking, KN-93, KN-62.
Difference in sequences of the Streptomyces globisporus 1912 and 2 its mutants
Authors: Polishchuk L. V.
Published: October 2020

Aim. The wild-type strain Streptomyces globisporus 1912 was isolated in 1967 from a sample of farmland (Armenia). Two mutants with different phenotypic characteristics were obtained (1912-2 and 1912-4Crt). The nucleotide sequences of 19 genes of the original strain and up to 90% of the genome sequence of its 2 mutants were determined. The aim of the study was to identify differences in the identified sequences of genomic DNA contigs of 2 mutants and individual genes of the original strain. Methods. BLASTN programs were used when comparing the DNA sequences. Results. BLAST analyzes of the sequences of 2 mutants S. globisporus (1912-2 and 1912-4Crt) revealed that they were identical (99.99%). Query cover of homologous sequences of mutants 1912-4Crt and 1912-4Crt was 95%. It was found that a number of mutant contigs (both 1912-2 and 1912-4Crt) were unique - their sequences were completely dissimilar to the sequences contigs of another variant. Conclusions. The determined sequences of genomes of 3 cultures will be useful in the construction of the genetic map of S. globisporus 1912. In addition, the comparative analysis of sequences of mutants can reveal the genetic basis of phenotypic changes.

Keywords: BLAST analysis, sequences, genome, cluster, gene, identity, overlap.