bluuebunny/crossref_metadata_2025 huggingface dataset:
AKUNTABILITAS, TRANSPARANSI DAN PERAN PERANGKAT DESA DALAM PENGELOLAAN ANGGARAN PENDAPATAN DAN BELANJA DESA DI DESA JENALAS KECAMATAN GEMOLONG KABUPATEN SRAGEN
Authors: Kusumaningrum Putri Dewi , Suharno Suharno , Widarno Bambang
Published: September 2022

This study aims to find out how the application of accountability, transparency and the role of village officials in the management of the Village Development Budget (APBDes) in Jenalas Village. This accountability and transparency in general in the government of Jenalas Village, Gemolong District, Sragen Regency has gone well, although there are still some weaknesses that must be addressed. according to the results of the analysis based on the stages of Village Fund management, namely at the stage of implementation, the implementation of rural infrastructure development activities, namely the construction of the cast road has been running as expected because the implementers of this development activity can be managed directly by the TeamImplementation of Activities formed by the Village Government.The sample in this study used 81 respondents from members of the Jenalas village community institution that were taken using the Purposive Sampling method. The results of the study identified that accountability, transparency and the role of village officials had a significant positive effect on the management of village income and expenditure budgets in Jenalas Village
ANALISIS FAKTOR YANG MEMPENGARUHI PELAPORAN KEUANGAN PERUSAHAAN MELALUI INTERNET
Authors: Ardiastuti Yuana , Widarno Bambang , Harimurti Fadjar
Published: September 2022

The purpose of this study is to analyze the effect of firm size, profitability, liquidity, and new shares offering to internet financial reporting. The samples used in the study were 114 manufacture companies listed on the Indonesia Stock Exchange in 2018 with proportional stratified sampling method. The analytical method used is logistic regression. The result of this study indicate that the variable new shares offering significant and positive impact to internet financial reporting, while other variables firm size, profitability, and liquidity are not significant impact to internet financial reporting.
PENGARUH FINANCIAL DISTRESS DAN AUDIT DELAY TERHADAP AUDITOR SWITCHING (Studi Kasus pada Perusahaan Sub Sektor Maknanan dan Minuman yang Terdaftar di Bursa Efek Indonesia Tahun 2013 – 2017)
Authors: Pratiwi Maharani Putri , Rispantyo Rispantyo , Harimurti Fadjar
Published: September 2022

The purpose of this study aims to find empirical evidence about the factors that influence auditor switching in food and beverage sub-sector companies listed on the Indonesia Stock Exchange. The factors tested in this study are financial distress and audit delay. The sample in this study used 14 food and beverage sub-sector companies listed on the Indonesia Stock Exchange in the period 2013 - 2017 taken using the Purposive Sampling method. These factors are then tested by logistic regression at a significance level of 5 percent. The results of the study identified that financial distress did not have a significant negative effect on auditor switching, while audit delay had a significant positive effect on auditor switching in the food and beverage sub-sector companies listed on the Indonesia Stock Exchange in 2013 - 2017.
PENGARUH KEADILAN,DISKRIMINASI, DAN PENALTY RATE TERHADAPpPERSEPSI WAJIP PAJAK ORANGpPRIBADI MENGENAI ETIKA PENGGELAPAN PAJAK DI KANTOR PELAYANAN PAJAK PRATAMA SURAKARTA
Authors: Revitasari Desya Noveria , Harimurti Fadjar , Kristianto Djoko
Published: September 2022

Analyzegthegsignificance of theneffect of justice, discriminationhand penalty rates on perceptionscof individualgtaxpayers regardingcthe ethics ofntax evasion. Data obtainedgthrough observation,ninterviews, distributiongof questionnaires, and.taking.documentation. Datapobtainedkthrough.the.distribution.of questionnaires to individual taxpayersgof thegSurakrta Pratama Tax Office. Thensample gused was a taxpayer in the city of Surakarta, whichkamounted to 100krespondents. Refinement technique in this research iskpurposivedsampling technique. The analyticalctool used isgmultiple linear regression. The resultsgof the studygconcluded that: 1). There is avsignificant effect of justice on thegethical perceptionsvof tax evasion, 2). There is agsignificant effect of discriminationkon ethicaldperceptions of tax evasion, and 3). .Therekispa significant effectkof penalty rates on ethical perceptions fof jtaxjevasion.
PENERAPAN STANDAR AKUNTANSI KEUANGAN ENTITAS MIKRO, KECIL, DAN MENENGGAH DAN PERHITUNGAN PAJAK TERHADAP PENERAPAN PERATURAN PEMERINTAH NO 23 TAHUN 2018 (Studi Kasus UD Mardi Mulyo Mebel Surakarta)
Authors: Kuryana Aviani , Harimurti Fadjar , Kristianto Djoko
Published: September 2022

Applicable Financial AccountingnStandards for Micro,nSmall, and Discouraging Entitiesn(SAK EMKM). The standard is used for the preparation of Financial Statements for MSMEs so that the financial statements in MSMEs are well organized and used for decision making. Along with the issuance of SAK EMKM accompanied by changes to the tax law namely Law No.23 of 2018 on Income Tax Article 4 paragraph 2 at a rate of 0.5%. The tax is a compulsory levy paid by the people to the state and will be used for various interests of the government and the general public. The results showed that the recording by UD Mardi Mulyo Furniture was manual which was used to find out the number of goods sold during one sales and purchase cycle, as well as in the payment of employee salaries, so the accounting record procedures performed by UD Mardi Mulyo Furniture were still far from SAK EMKM and UD Mardi Mulyo Furniture has not calculated taxes according to the tariffs based on PP No. 23 of 2018 so that the information obtained from the notes cannot be used fully to support or be useful in making decisions more thoroughly from the operational activities of UD Mardi Mulyo Furniture. The causal factor which becomes an obstacle in preparing financial reports and performing tax calculations is the absence of a clear division of tasks between fields due to lack of knowledge about bookkeeping and taxation. The owner manages his own business, so his time is focused on working on and developing the business. This type of data usesnqualitative and quantitative. The data source uses primary data andnsecondary data. Data analysisntechniques using descriptive analysis.
ANALISI FAKTOR-FAKTOR YANG PENGARUHI PAJAK DAERAH KABUPATEN EKS-KARESIDENAN SURAKARTA
Authors: Gunawan Shodhik Ade , Harimurti Fadjar , Sunarti Sunarti
Published: September 2022

This study aims to examine the influence and analysis of PDRB, population, inflation and number of industries on the tax revenue of the ex-residency district of Surakarta. This study uses a survey method as an instrument. The population of this study is LKPD and BPS data of the Surakarta Ex-Residency District. Based on the purposive sampling method, the number of samples obtained was 35 data. This type of research used in this research is quantitative research with the aim to uncover the truth contained in this research problem with multiple regression testing and class assumption testing and data analysis to determine the quality used with the help of SPSS 25 software.

The results of this study indicate that partially PDRB variable, Total Population, Inflation and Number of industries affect the Local Tax Revenue. This research is expected to be able to provide useful input for regional governments to synergize with each other to further increase Regional Tax Revenues.
FAKTOR-FAKTOR YANG MEMPENGARUHI TINGKAT KESEHATAN PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Priseillia Santoso Rut Oryza , Nany Magdalena , Suprayitno Suprayitno
Published: September 2022

Few researches on financial distress give different results of predicting a company’ s financial distress. Financial distress is an early warning of bankruptcy, that a company has a financial failure, so that if it is not quickly well handled and getting worse, it goes to bankruptcy. The objective of this research was to give empirical evidence about the effects of net income/equity, total liabilities/total assets, sales growth, cost of goods sold/inventory, sales/account receivable, account receivable/total assets on company’s financial health both partially and simultaneously. Thirty one financial data from 31 manufacturing emitents listing at Jakarta Stock Exchange were analyzed by by multiple regression analysis. The results show that cost of goods sold/ inventory ratio significantly have positive effect on company’s financial health. Net income/equity ratio insignificantly have negative effect on company’s financial health. While total liabilities/total assets, sales growth, sales/account receivable and account receivable/total assets ratios insignificantly have positive effect on company’s financial health. The results also show that net income/ equity, total liabilities/total assets, sales growth, cost of goods sold/ inventory, sales/ account receivable, account receivable/total assets ratios have significant effect on company’s financial health.
PENGARUH INFLASI, NILAI TUKAR RUPIAH, SUKU BUNGA DAN SELF ASSESSMENT SYSTEM TERHADAP PENERIMAAN PAJAK PERTAMBAHAN NILAI DI KANTOR WILAYAH DIREKTORAT JENDRAL PAJAK JAWA TENGAH II
Authors: Junianto Setiawan , Harimurti Fadjar , Suharno Suharno
Published: September 2022

Value Added Tax (VAT) is a tax that is imposed on the consumption of goods and services in the customs area. The purpose of this study is to examine the effect of inflation, the rupiah exchange rate, interest rates and self assessment system on value added tax receipts. The population of this study is the inflation rate in Central Java, the exchange rate of the rupiah against one US Dollar based on the tax rate, Bank Indonesia reference interest rate, the number of VAT notification period and all VAT receipts in the Central Java Regional Tax Office

II with monthly data for the 2015- 2019. The data analysis technique used is descriptive analysis, the classic assumption test and the coefficient of determination (R2). The results of the study concluded that inflation and interest rates did not significantly influence VAT revenue, while the rupiah exchange rate and self assessment system had a significant positive effect on VAT revenue.
PENGARUH PENGENDALIAN INTERN AKUNTANSI, PEMANFAATAN TEKNOLOGI INFOMASI DAN KAPASITAS SUMBER DAYA MANUSIA TERHADAP KEANDALAN DAN KETEPATAN WAKTU PELAPORAN KEUANGAN PEMERINTAH DAERAH (Studi Kasus di OPD Kota Surakarta)
Authors: Susilawati Octalia Risha , Suharno Suharno , Widarno Bambang
Published: September 2022

The purpose of this research is to examine the effect of accounting internalcontrols, theause of information technology, and human resources capacity on thereliability and timeliness of financial reporting in local governments. The objectof this research was the staff accounting of the OPD in Surakarta City. Type ofdata uses in this research is primary data and the population was 33 OPDD inSurakarta City. The data obtained by quetionnaires. The data were analyzed byusing multiple linear regression analysis. Technique of data analysis use a classicassumptionatest, multiplealinear regression analysis, t-test, F-test and coefficientof determination(R2). Results of this research indicate that accounting internalcontrol, the use of information technology and human resources capacityoversight a positive significant influence on the reliability and timeliness offinancial reporting in thealocal governments in the Surakarta City.
PENGARUH PROFESIONALISME, AMBIGUITAS PERAN DAN KOMITMEN ORGANISASI TERHADAP KINERJA AUDITOR (Studi Empiris pada KAP di Kota Surakarta dan Yogyakarta)
Authors: Putri Ine Noviana , Rispantyo Rispantyo , Widarno Bambang
Published: September 2022

This isresearch was conducted toodetermine theeeffect off professionalism,role ambiguity, organizational commitment on the auditor performance. Thisstudy uses primary data from the answers to questionnaires distributed toauditors at KAP in Surakartas and Yogyakarta. The sampling technique was takenusing purposivensampling method, amounting too32 respondent. Data analysistechniques used in this study were descriptive statistical tests, validity tests,reliability tests, classic assumption tests, multiple linear regression analysis tests,t tests, F tests, and determination tests (R2). Based on the results of data analysisthe effect of professionalism on the auditor performance obtained a positivecoefficient and significant effect. Thee effect off role ambiguity onn the tendencyauditor performancee obtained negative coefficient and significant effect. Theeffectnofforganizationaliscommitmentoon the auditorsperformance is obtainedpositive coefficient and significant effect. The suggestion in this research is toincrease the research object, namely not only KAP in Surakarta and YogyakartaCity and to add moderating or intervening variables.
PENGARUH GOOD GOVERNANCE TERHADAP KUALITAS LAPORAN KEUANGANKDENGAN SISTEM PENGENDALIAN INTERNAL SEBAGAI PEMODERASI (Studi Kasus Pada Aparatur Organisasi Perangkat Daerah Kab. Karanganyar)
Authors: Hosana Amanda Thea , Rispantyo Rispantyo , Widarno Bambang
Published: September 2022

This study was conducted to determine the effect of good governance onthe quality of local government financial reports, the effect of internal controlsystems on>the quality of local government financial reports, the internalcontrol system moderates the effect of good governance on the quality of localgovernment financial reports. This study uses primary data from the answersto the questionnaires distributed to officials of the Karanganyar RegencyRegional Government Organization. The sampling technique was taken usingpurposive sampling method, amounting to 72 respondents. The data analysistechnique used in this research is descriptive statistical test, validity test,reliability test, classical assumption test, multiple linear regression analysistest, t test, F test, determination test (R2) and MRA absolute difference test.The result of the research states that good governance and internal controlsystems have a significant positive effect. The result of moderation regressionanalysis with absolute difference value test shows that the internal controlsystem isn’t able to negatively moderate the relationship of good governance tothe quality of local government financial reports.
ANALISIS FAKTOR-FAKTOR YANG MEMENGARUHI PENERAPAN KONSERVATISME AKUNTANSI
Authors: Ridho Muhammad , Arianto Dwi
Published: September 2022

Penelitian ini bertujuan untuk menguji Faktor-faktor yang memengaruhi konservatisme akuntansi pada perusahaan manufaktur sector makanan di Bursa Efek Indonesia (Periode 2018-2020). Faktor-faktor yang diuji adalah rasio leverage, ukuran perusahaan, intensitas modal, serta kepemilikan manajerial. Penelitian ini menggunakan 15 perusahaan manufaktur sektor makanan yang terdaftar di Bursa Efek Indonesia periode 2018-2020 sebagai sampel penelitian. Pengujian hipotesis menggunakan model analisis regresi 2018-2020 untuk menguji rasio leverage, ukuran perusahaan, intensitas modal, serta kepemilikan manajerial terhadap konservatisme akuntansi. Hasil penelitian menunjukkan bahwa ukuran perusahaan, intensitas modal dan kepemilikan manajerial berpengaruh positif terhadap konservatisme akuntansi, sedangkan rasio leverage berpengaruh negatif terhadap konservatisme akuntansi.

 

Kata kunci: rasio leverage, ukuran perusahaan, intensitas modal, kepemilikan manajerial.
CREATIVE PROCESS OF HALANG DANCE
Authors: Yulianti Ninik Putri , Soemaryatmi Soemaryatmi
Published: September 2022

Halang dance is a choreographic work that departs from a folk tale, namely the love story of Raden Inu Kertapati with Galuh Candra Kirana who faces many obstacles. The formulation of the research problem, namely: How is the creative process of creating Halang dance? This study uses a practice-based research methodology. The creative process in creating this dance uses the 3R theory. The result shows that the artistic process gives freedom of interpretation and creativity to anyone to realize ideas in the form of works. Halang dance is a work of art that is done through a creative process by going through the steps of Re-Visiting, Re-Questioning, and Re-Interpreting. Then through the steps of the creation process, namely exploration, improvisation, composition, evaluation, rehearsal, and performing. Halang dance is performed by four scenes as a literal dramatic choreography. The elements in Halang dance are able to convey the atmosphere and message to the audience that in truth life will never be separated from all problems and love will continue to grow and develop in souls who have sincerity.
economía de las luces: reformas de los aranceles postales y dinámica de la circulación de la impresión en el siglo XIX en Brasil
Authors: Goldfeder Borges de Castro Pérola Maria
Published: September 2022

Este artículo tiene como objetivo presentar uno de los temas transversales de nuestra investigación doctoral recientemente completada, a saber: el lugar de lo impreso en la economía política del Imperio relacionada con las comunicaciones. Para ello, analizamos el evolutivo de la legislación tarifaria postal, su discusión en los diferentes ámbitos de representatividad (Cámara /Senado/Prensa) y las estadísticas de Correos relacionadas con el volumen, categoría y dirección de los flujos de correspondencia.
De Moravia a Buenos Aires: la Presencia de Francisco Latzina en la construcción de sentido y en el origen de la sociología en argentina
Authors: Castiglione Celeste
Published: September 2022

El presente trabajo busca ofrecer una lectura contextualizada de un fragmento del Censo de 1914 escrito por Francisco Latzina (1843-1922), migrante del Imperio Austro-Húngaro, que formaba parte de la élite política e intelectual que gobernó la Argentina de 1880 a 1916, pero que proyecta su discurso hasta el presente.

En su figura confluyen una multiplicidad de niveles: las corrientes que conforman una Sociología argentina embrionaria, las migraciones tempranas que aportan una construcción étnica e identitaria particular, la formación de cuadros intelectuales que asumen un registro de observación al otro y en este caso específico con el estudio de su muerte se revelan desde su enfoque positivista en toda su contradictoria complejidad.
complejo vial ferroviario argentino en el siglo XX. La evolución del transporte de cargas
Authors: Gómez Milo Teresita , Tchordonkian Silvia
Published: September 2022

La evolución del transporte de cargas terrestre en Argentina en los últimos dos siglos, en medio del desarrollo ferroviario primero y en el auge automotriz después, pone en una relación conflictiva al sistema productivo y la capacidad instalada de movilizar la producción. Nuestro objetivo es dar cuenta de los cambios vinculados con la propiedad, el efectivo control y los ámbitos de desarrollo del movimiento de cargas que según las etapas mejoran o complican el servicio de transporte. Evaluamos el impacto de los ajustes llevados adelante en los años 90 que prometían dotar al país de un sistema eficiente de transportes, referenciado en los modelos del primer mundo. Este trabajo es continuidad de una serie de presentaciones anteriores enmarcadas en un proyecto UBACYT. El recorrido bibliográfico y las estadísticas son producción de especialistas en el tema y recursos generados en organismos nacionales.
Repensando y desandando el proceso de investigación en tiempos de virtualidad en contexto de Pandemia
Authors: Heinrich Alejandro , Odetti Verónica Beatriz , Sampietro Juliana
Published: September 2022

El presente artículo tiene por objetivo presentar una reseña de ciertas  dimensiones del proceso metodológico de una investigación realizada en el marco del Estudio nacional sobre las modificaciones en los consumos de sustancias y las respuestas políticas implementadas a partir del Aislamiento Social Preventivo y Obligatorio (ASPO) por COVID-19, llevada a cabo por la cátedra de Psicología Social de la Facultad de Humanidades Artes y Ciencias Sociales de la Universidad Autónoma de Entre Ríos en conjunto con la Secretaría de Políticas Integrales sobre droga de la Nación Argentina (SEDRONAR). Dicha investigación, comprende una revisión, análisis y reflexión del proceso de investigación, las implicancias, desafíos y potencialidades del trabajo remoto en contexto de pandemia durante el 2020.
Estudio de las competencias culturales en estudiantes universitarios de Licenciatura en Turismo.
Authors: Martín Zamora Yoanna , Velastegui López Luis Efraín
Published: September 2022

El presente trabajo versa en el debate planteado por el perfeccionamiento de la formación de los Licenciados en Turismo, a partir de la mejora continua del Plan de Estudios en la Educación Superior cubana, incluso en el escenario de la COVID 19. El objetivo perseguido es, precisamente, determinar el impacto en la formación de competencias culturales en los estudiantes universitarios de Turismo para su futuro desempeño profesional a través de métodos no presenciales. Ello se materializa mediante el análisis de los elementos que conducen a la conformación de las competencias culturales, las cuales se definen como concepto a partir del análisis de los criterios de diferentes autores. En tal dirección, se exponen las ideas de especialistas, docentes, empleadores y estudiantes de la carrera, mediante la bibliografía consultada, encuestas, la aplicación del Método Delphi, entre otros para determinar el impacto de la teleformación en cada una de las competencias culturales necesarias para el Licenciado en Turismo y evaluar su desarrollo a través de su formación profesional durante los dos últimos cursos a través del uso del Entorno Virtual de Enseñanza Aprendizaje (EVEA). Todo esto se rige, esencialmente, por las exigencias del mundo laboral a los profesionales desde la preparación, evidenciado, además, en las habilidades funcionales básicas y específicas contenidas en el currículo del estudiante. Luego, se ofrecen acciones que favorecen la mejora de la formación de los futuros licenciados y la sistematización de lo ya logrado en cuanto a competencias culturales se refiere.
PENERAPAN MODEL PEMBELAJARAN PROBLEM BASED LEARNING UNTUK MENINGKATKAN KETERAMPILAN BERPIKIR KRITIS KONSEP KALOR PADA SISWA KELAS XI-IPA-1 DAN XI-IPA-2 SMA NEGERI 5 KOTA TERNATE
Authors: Umar Saputri Hi , Balulu Nasrun
Published: September 2022

Penelitian ini bertujuan untuk mengetahui peningkatan keterampilan berpikir kritis siswa pada konsep kalor dengan menggunakan model pembelajaran Problem Based Learning. Penelitian ini mengikuti rancangan one-group pretest and posttest. Jenis penelitian ini adalah penelitian eksperimen.  Metode yang digunakan dalam penelitian ini adalah  metode deskriptif kuantitatif. Berdasarkan hasil analisis data, dapat disimpulkan bahwa model  pembelajaran Problem Based Learning yang terdiri atas lima  sintaks yaitu orientasi, mengorganisasi, investigasi, menyajikan hasil data, dan evaluasi  Hasil penelitian menunjukkan bahwa pembelajaran yang dilaksanakan dengan model pembelajaran  Problem Based Learning, dapat meningkatkan keterampilan berpikir kritis siswa dengan kategori sedang dan tinggi untuk XI-MIPA-1 dengan rata-rata N-Gain 63.80% dan keterampilan berpikir kritis siswa dengan kategori sedang dan tinggi untuk XI-MIPA-2 dengan rata-rata N-Gain 69.89%. Pengujian normalitas di kelas MIPA-1 diperoleh data 2hit <2tab atau 5,39 < 35,175 dengan dk 23 dan taraf signifikansi (α)  0,05 atau 5%. Maka dapat disimpulkan bahwa data distribusi normal dan Pengujian normalitas di kelas MIPA-2 diperoleh data 2hit <2tab atau 7,06<30,144 dengan dk 19 dan taraf signifikansi (α)  0,05 atau 5%. Dengan demikian Ha ditolak dan Ho diterima. Artinya tidak terdapat perbedaan peningkatan yang signifikan pada penerapan model pembelajaran Problem Based Learning di kelas MIPA-1 dan MIPA-2. Maka dapat disimpulkan bahwa penerapan model pembelajaran Problem Based Learning konsisten dalam penerapannya di kelas.
CONTEXTUAL TEACHING AND LEARNING (CTL) MODEL TO IMPROVE STUDENTS’ VOCABULARY
Authors: Rajab Sitna Hawa , Ajam Ali , Syawal Asrul M.
Published: September 2022

Tujuan dari penelitian ini adalah untuk mengetahui sejauh mana pengunaan model Ctl dalam belajar bahasa inggris terutama pada kosakata, pada siswa kelas dua MTS Nurul Hidayah Bobaneigo. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif dengan uji-t. Populasi dalam penelitian ini adalah siswa MTS Nurul Hidayah Bobaneigo yang khusnya kelas VII A yang terdiri dari 2 kelas yang berjumlah 42 siswa diantaranya pria 18 dan wanita 24. Sampelnya adalah 21 orang siswa kelas VII A. Peneliti memberikan tes sebelum treatment tentang kosakata, dan kemudian memberikan posttest setelah treatment. Hal ini dapat dilihat dalam hasil posttest menunjukan bahwa dari 21 siswa 2 siswa memperoleh luar biasa, 10 siswa memperoleh sangat baik, 6 siswa memperoleh baik, dan 3 siswa memperoleh cukup baik. Bahwa skor rata-rata di posttest 1.825. Lebih rendah di skor rata-rata di pretest 1.165. Berdasarkan data diatas pemahaman siswa masih rendah sebelum belajar melalui model pembelajaran CTL. Nilai t-test 4.48 lebih tinggi dari t-table 1.725 pada tingkat signifikan 0.05 itu adalah derajat kebebasan 20. Ini berarti bahwa Hi diterimah dan Ho ditolak. Hal ini menunjukan bahwa pengunaan model pembelajaran CTL signifikan untuk mengajar kosakata di siswa MTS Nurul Hidayah Bobaneigo.
MENINGKATKAN KEMAMPUAN MEMBACA PEMAHAMAN MENGGUNAKAN STRATEGI KNOW WANT TO LEARN (KWL) PADA SISWA KELAS V SD INPRES 15 HALMAHERA BARAT
Authors: Awa Meike , Abdullah Suhardi , Karim Kodrat Hi. , Marasabesy Anwar
Published: September 2022

The research objectives consist of (1) To increase students reading comprehension understanding in using Know Want and To Learn strategy and (2) To Describe the students reading comprehension ability in using this teaching strategy by the students of 5th grade  SD Inpres Halmahera Barat. Classroom action research has become the kind or type of research that used it. Thus the research consists of planning, action, observation, and reflection. Also, this research used quantitative and qualitative approaches in determining the data analysis. The data considered by the testing process, observation activities (between students and teachers), and also students post-test. The result of both cycles was as follows: (1) the student’s reading comprehension ability score averages at the first cycle were 70 and in the second cycle became 95. It means that the learning strategy functions better in the process and also students’ capability in reading comprehension learning objectives is reached.
THINK PAIR SHARE (TPS) TERINTEGRASI SAINTIFIK UNTUK MENINGKATKAN HASIL BELAJAR IPA DI SMP
Authors: Ajhar Ajhar , Haerullah Ade , Bahtiar Bahtiar
Published: September 2022

Various efforts are made to improve education quality in schools become a priority. One of the efforts that can be taken is to improve the quality of the learning process. Improving the quality of the learning process can be done by increasing the potential of the teacher as one of the elements in the learning process. The purpose of this study was to obtain student learning outcomes by implementing cooperative learning model of the type of think pair share (TPS) integrated with additives and addictive substances in food and drinks at a State Junior High School 1West Halmahera. This research is a quasi-experimental design, consisting of two experimental classes with one group pretest-posttest research design. The results showed that the think Pair share (TPS) learning model integrated scientific was able to improve student learning outcomes in additives and addictive substances in food and drinks. The pieces of evidence can be seen by the average increase in student learning outcomes before after treatment 40.84 to 73.06. Thus it can be concluded that the Think Pair Share learning model integrated science has the potential to improve student cognitive learning outcomes.
PRIMARY SCHOOL STUDENTS IN RURAL INDONESIA CONSTRUCTED IN A PHOTO: SOCIAL JUSTICE, EQUITY, AND ACCESS TO EDUCATION
Authors: Sutaryo Sutaryo
Published: September 2022

The purpose of this paper is to examine how primary schools students in rural Indonesia are constructed in a photo. The paper discusses issues on social justice, equity, and access to education for primary school students in rural Indonesia as visually represented in the photo. Thematic analysis is used within the context of critical approach by referring to relevant literatures. Why the photo as an interesting primary source for qualitative research is selected and why the thematic analysis and the critical approach are applied in this paper are briefly described.
ANALISIS KEAKTIFAN BELAJAR SISWA PADA PEMBELAJARAN PPKN MELALUI PENERAPAN METODE KERJA KELOMPOK DI KELAS IV SD NEGERI 50 KOTA TERNATE
Authors: Taher Novita M , Karim Kodrat Hi , Wulandari Selvi
Published: September 2022

These study aims are (1) to determine student learning activities by applying group work methods in class IV SD Negeri 50 Ternate City (2) to find out what student learning activities are through the application of group work methods to class IV SD Negeri 50 Ternate City. The method used in this research is the descriptive qualitative method. Data collection techniques used in this research are, observation, interview, and documentation. This study indicates students' activeness in learning PPKN by applying the group work method in class IV SD Negeri 50 Ternate City. That is, some factors that cause students to be active in PPKN learning are before learning, the teacher should give directions first regarding the material to be discussed later, and if the material is related to the rights and obligations of the teacher, always provide examples that fit / easy so that students quickly understand the material. The factors from the family environment are (students/parents) who have limited cellphones if students get assignments related to the national anthem, students must ride or borrow friends' cellphones, students who do not have internet/data packages, some parents who are busy working (traders) so that they cannot help students in completing their homework (PR). The other factors that cause student activity in PPKN lessons are (that some students already understand Indonesian history, some already understand and have memorized the points of Pancasila, memorize national songs, already understand the rights and obligations).
Assessing Agreement Between Upright and Supine Head Roll Tests for Horizontal Semicircular Canal Benign Paroxysmal Positional Vertigo
Authors: Kim Tae Ho , Han Jae Sang , Han Jae Hong , Lee Dong-Hee , Kim Yeonji , Park Shi Nae , Park Kyoung-Ho , Seo Jae-Hyun
Published: September 2022

Background and Objectives The newly introduced upright head roll test (UHRT), which exploits head rotations in the roll plane with the patient in the upright sitting position, is a diagnostic maneuver for horizontal canal-benign paroxysmal positional vertigo (HC-BPPV). This study is designed to determine whether UHRT, compared to supine head roll test (SHRT), can more accurately diagnose HC-BPPV and determine the subtype of HC-BPPV.Subjects and Method A total of 455 video nystagmus tests performed between April 2019 to June 2021 were retrospectively reviewed, and 63 patients with direction-changing positional nystagmus at UHRT or SHRT were enrolled in this study. UHRT result was classified as negative (if no nystagmus was observed), positive incomplete (if nystagmus was detected in one side), and positive complete (if nystagmus was evoked in both side). The frequency of nystagmus is also included in our assessment. In addition, the results of 4 patients with bow and lean test (BLT) records on videonystagmography were also analysed.Results The concordance rate between UHRT and SHRT was 97.8%, and the positive concordance rate was 91.38%. UHRT and SHRT provided identical subtype diagnosis in 98.1% (52 of 53 cases). In one case, UHRT and SHRT showed opposite results. Evaluating the affected side with bow and lean records, the SHRT, UHRT and BLT showed consistent results. The mean frequency of nystagmus was faster in SHRT than in UHRT.Conclusion UHRT showed equivalent results to SHRT in distinguishing subtype of HC-BPPV. UHRT is a useful method in diagnosing HC-BPPV simply in a sitting position.
Treatment of Barrett's esophagus with low-grade dysplasia using Hibrid-APC
Authors: Armenteros Torres Mildred Cecilia , Quintanilla Raúl Antonio Brizuela , de Oca Megias Elizabeth Montes , Escobar Vivianne María Anido , Contino Norberto C. Alfonso
Published: September 2022

Introduction: Barrett's esophagus (BE) with low-grade dysplasia represents a risk of progression towards esophageal adenocarcinoma. Hybrid-APC turns out to be an effective, safe, easy to use and relatively low-cost technique to stop this progression. Aims: to describe the therapeutic response of Hybrid-APC in patients with low-grade dysplasia in Barrett's esophagus. Method: an observational, descriptive investigation of a series of cases was carried out at the National Center for Minimal Access Surgery between December 2018 and December 2020. Twenty patients with BE histologically classified with low-grade dysplasia were included. Ablation with Hybrid APC was applied, and endoscopy was performed three and six months after the end of the treatment. The therapeutic response was evaluated through histological remission and the presence of complications. The information was processed in the statistical program SPSS, version 21. Results: mean age 50.5 (range 27-81 years). 55% (11) are male. Eighty-five percent were asymptomatic and 90% had circumferential BE. 55% (11) required a HybridAPC session. With an average of 1.4 sessions, macroscopic and histological remission without dysplasia was achieved at three and six months in 90% (18/20) and 92.8% (13/14) of the patients respectively, without witnessing complications. Conclusions: endoscopic treatment with the Hybrid-APC has a good therapeutic response, with a good histological remission and without complications, in patients with low-grade dysplasia in BE.
Management of Thrombosis in High-Risk Patients: Focus on Cancer-Associated Thrombosis
Authors: Thomas Mari , Bolton-Maggs Paula , Agnelli Giancarlo
Published: September 2022

This symposium took place during the International Society on Thrombosis and Haemostasis (ISTH) Congress, 2022. Ajay Kakkar, Thrombosis Research Institute, London, UK, opened the symposium by highlighting the extent to which patients with cancer are affected by thrombotic disease. Subsequently, Mari Thomas, University College London, UK, described the current treatment options for patients with cancer-associated thrombosis (CAT). Thomas highlighted the current unmet needs faced by these patients, with the risk of bleeding continuing to be the main issue affecting anticoagulation treatment. Paula Bolton-Maggs, University of Manchester, UK, and UK Haemovigilance Scheme, Manchester, UK, gave an overview of Factor XI (FXI) inhibition and outlined why this factor is a potential attractive anticoagulation drug target. Multiple therapies targeting FXI are currently in development, with seven clinical trials published to date.1-7 Although there are some similarities between these agents, there are also many differences in terms of their administration route and frequency, the timing of onset of action, and methods of metabolism and excretion. Giancarlo Agnelli, University of Perugia, Italy, and Istituti Clinici Scientifici (ICS) Maugeri, Pavia-Milan, Italy, then described the importance of conducting clinical trials that are designed to address the unmet needs of patients with CAT. In particular, he highlighted the ongoing Phase III ASTER and MAGNOLIA studies that are aiming to demonstrate that the FXI inhibitor abelacimab is superior to standard of care treatments in terms of bleeding rates for patients with CAT, including those with gastrointestinal (GI) or genitourinary (GU) tumours. Concluding remarks were given by Gary Raskob, University of Oklahoma Health Sciences Center, Oklahoma City, USA, who re-emphasised the unmet needs in the treatment of CAT, and the promise that FXI inhibitors hold for the future.
Hybrid cell line development system utilizing site-specific integration and methotrexate-mediated gene amplification in Chinese hamster ovary cells
Authors: Min Honggi , Kim Seul Mi , Kim Dongwoo , Lee Solhwi , Lee Sumin , Lee Jae Seong
Published: September 2022

Site-specific integration has emerged as a promising strategy for streamlined and predictable Chinese hamster ovary (CHO) cell line development (CLD). However, the low specific productivity of the targeted integrants limits their practical application. In this study, we developed a hybrid CLD platform combining site-specific integration of a transgene and dihydrofolate reductase/methotrexate (DHFR/MTX)-mediated gene amplification to generate high-producing recombinant CHO cell lines. We used the CRISPR/Cas9-based recombinase-mediated cassette exchange landing pad platform to integrate the DHFR expression cassette and transgene landing pad into a CHO genomic hot spot, C12orf35 locus, of DHFR-knockout CHO-K1 host cell lines. When subjected to various MTX concentrations up to 1 μM, EGFP-expressing targeted integrants showed a 3.6-fold increase in EGFP expression in the presence of 200 nM MTX, accompanied by an increase in the DHFR and EGFP copy number. A single-step 200 nM MTX amplification increased the specific monoclonal antibody (mAb) productivity (qmAb) of recombinant mAb-producing targeted integrants by 2.8-folds, reaching a qmAb of 9.1–11.0 pg/cell/day. Fluorescence in situ hybridization analysis showed colocalization of DHFR and mAb sequences at the intended chromosomal locations without clear amplified arrays of signals. Most MTX-amplified targeted integrants sustained recombinant mAb production during long-term culture in the absence of MTX, supporting stable gene expression in the amplified cell lines. Our study provides a new CLD platform that increases the productivity of targeted integrants by amplifying the transgene copies.
A possible connection between reactive oxygen species and the unfolded protein response in lens development: From insight to foresight
Authors: Gao Lixiong , Jin Ni , Ye Zi , Ma Tianju , Huang Yang , Li Hongyu , Du Jinlin , Li Zhaohui
Published: September 2022

The lens is a relatively special and simple organ. It has become an ideal model to study the common developmental characteristics among different organic systems. Lens development is a complex process influenced by numerous factors, including signals from the intracellular and extracellular environment. Reactive oxygen species (ROS) are a group of highly reactive and oxygen-containing molecules that can cause endoplasmic reticulum stress in lens cells. As an adaptive response to ER stress, lens cells initiate the unfolded protein response (UPR) to maintain normal protein synthesis by selectively increasing/decreasing protein synthesis and increasing the degradation of misfolded proteins. Generally, the UPR signaling pathways have been well characterized in the context of many pathological conditions. However, recent studies have also confirmed that all three UPR signaling pathways participate in a variety of developmental processes, including those of the lens. In this review, we first briefly summarize the three stages of lens development and present the basic profiles of ROS and the UPR. We then discuss the interconnections between lens development and these two mechanisms. Additionally, the potential adoption of human pluripotent stem-cell-based lentoids in lens development research is proposed to provide a novel perspective on future developmental studies.
Mouse embryo phenotyping using X-ray microCT
Authors: Handschuh Stephan , Glösmann Martin
Published: September 2022

Microscopic X-ray computed tomography (microCT) is a structural ex vivo imaging technique providing genuine isotropic 3D images from biological samples at micron resolution. MicroCT imaging is non-destructive and combines well with other modalities such as light and electron microscopy in correlative imaging workflows. Protocols for staining embryos with X-ray dense contrast agents enable the acquisition of high-contrast and high-resolution datasets of whole embryos and specific organ systems. High sample throughput is achieved with dedicated setups. Consequently, microCT has gained enormous importance for both qualitative and quantitative phenotyping of mouse development. We here summarize state-of-the-art protocols of sample preparation and imaging procedures, showcase contemporary applications, and discuss possible pitfalls and sources for artefacts. In addition, we give an outlook on phenotyping workflows using microscopic dual energy CT (microDECT) and tissue-specific contrast agents.
Biological benefits of collective swimming of sperm in a viscoelastic fluid
Authors: Phuyal Shiva , Suarez Susan S. , Tung Chih-Kuan
Published: September 2022

Collective swimming is evident in the sperm of several mammalian species. In bull (Bos taurus) sperm, high viscoelasticity of the surrounding fluid induces the sperm to form dynamic clusters. Sperm within the clusters swim closely together and align in the same direction, yet the clusters are dynamic because individual sperm swim into and out of them over time. As the fluid in part of the mammalian female reproductive tract contains mucus and, consequently, is highly viscoelastic, this mechanistic clustering likely happens in vivo. Nevertheless, it has been unclear whether clustering could provide any biological benefit. Here, using a microfluidic in vitro model with viscoelastic fluid, we found that the collective swimming of bull sperm in dynamic clusters provides specific biological benefits. In static viscoelastic fluid, clustering allowed sperm to swim in a more progressive manner. When the fluid was made to flow in the range of 2.43–4.05 1/sec shear rate, clustering enhanced the ability of sperm to swim upstream. We also found that the swimming characteristics of sperm in our viscoelastic fluid could not be fully explained by the hydrodynamic model that has been developed for sperm swimming in a low-viscosity, Newtonian fluid. Overall, we found that clustered sperm swam more oriented with each other in the absence of flow, were able to swim upstream under intermediate flows, and better withstood a strong flow than individual sperm. Our results indicate that the clustering of sperm can be beneficial to sperm migrating against an opposing flow of viscoelastic fluid within the female reproductive tract.
The guiding value of hybrid resting full-cycle ratio and fractional flow reserve strategy for percutaneous coronary intervention in a Chinese real-world cohort with non-ST elevation acute coronary syndrome
Authors: Lei Yumeng , Zhang Shuaiyong , Li Mengyao , Wang Jiawang , Wang Yunfei , Zhao Lei , Yan Wei , Chen Ming , Su Yanjie , Yu Jing , Yu Na , Dong Tongjun , Cao Xufen , Yan Liqiu
Published: September 2022

Objective

The study aimed to assess the correlation and agreement between resting full-cycle ratio (RFR) and fractional flow reserve (FFR), and evaluate the guiding value of a hybrid RFR-FFR strategy for percutaneous coronary intervention (PCI) in a Chinese real-world cohort with non-ST elevation acute coronary syndrome (NSTE-ACS).

Materials and methods

A total of 109 patients with NSTE-ACS (149 diseased vessels), who underwent an invasive physiological assessment in Cangzhou Central Hospital, Hebei Medical University, were prospectively enrolled from September 2021 to May 2022. FFR ≤ 0.80 was used as the gold standard for coronary artery functional ischemia. We utilized the Pearson correlation and Bland-Altman analysis to assess the correlation and agreement between RFR and FFR. The diagnostic value of RFR predicting FFR ≤ 0.80 was evaluated in accordance with the receiver operating characteristic (ROC) curve. The hybrid RFR-FFR strategy, which was established according to determining the “gray zone” of RFR (FFR was further assessed using vasodilators only for diseased vessels in the “gray zone”), needed to afford over 95% global agreement with the FFR-only strategy.

Results

Resting full-cycle ratio was significantly linearly linked with FFR (R2 = 0.636, P < 0.001). The accuracy, specificity, and sensitivity for RFR ≤ 0.89 predicting FFR ≤ 0.80 were 81.2, 70.8, and 86.1%, respectively. The area under the ROC curve for RFR predicting FFR ≤ 0.80 was 0.881 (P < 0.001), and the cutoff value was 0.90. The “gray zone” of RFR was 0.85–0.93. The positive and negative predictive values of the hybrid RFR-FFR strategy were 0.95 and 0.93, respectively. The hybrid RFR-FFR strategy exhibited an agreement of 96.0% with FFR and obviated the need for a vasodilator by 60.4%.

Conclusion

Resting full-cycle ratio and FFR have high correlation and consistency. The hybrid RFR-FFR strategy highlights considerably enhanced agreement with the FFR-only strategy, whilst making the requirement of vasodilator administration less than a half.
Personal mental health navigator: Harnessing the power of data, personal models, and health cybernetics to promote psychological well-being
Authors: Rahmani Amir M. , Lai Jocelyn , Jafarlou Salar , Azimi Iman , Yunusova Asal , Rivera Alex. P. , Labbaf Sina , Anzanpour Arman , Dutt Nikil , Jain Ramesh , Borelli Jessica L.
Published: September 2022

Current digital mental healthcare solutions conventionally take on a reactive approach, requiring individuals to self-monitor and document existing symptoms. These solutions are unable to provide comprehensive, wrap-around, customized treatments that capture an individual’s holistic mental health model as it unfolds over time. Recognizing that each individual requires personally tailored mental health treatment, we introduce the notion of Personalized Mental Health Navigation (MHN): a cybernetic goal-based system that deploys a continuous loop of monitoring, estimation, and guidance to steer the individual towards mental flourishing. We present the core components of MHN that are premised on the importance of addressing an individual’s personal mental health state. Moreover, we provide an overview of the existing physical health navigation systems and highlight the requirements and challenges of deploying the navigational approach to the mental health domain.
Necrotizing periodontal disease in a nutritionally deficient patient: A case report
Authors: Sheng Sally , Kim Haemin H. , Meng Hsiu-Wan , Tribble Gena D. , Chang Jennifer
Published: September 2022

Necrotizing periodontal disease (NPD) is a microbial infectious inflammatory disease of the gingiva and/or periodontium that is characterized by a rapid onset of inflammation, pain, and “punched out” cratered interdental papillae. Although NPD is not very common, diagnosis is mostly based on its unique clinical presentation. Some predisposing factors for developing NPD include poor oral hygiene, smoking, malnutrition, immunosuppression (such as in HIV infection, uncontrolled diabetes, and cancer), and stress. This report presents the case of a 22-year-old Caucasian woman, who was a heavy smoker but with otherwise showed no systemic disease and who suffered from severe inflammation of the gingiva, ulceration, and necrosis of the interdental papillae, and pseudomembrane formation. The patient had been hospitalized for a seizure episode and was diagnosed with malnutrition-induced seizure. NPD was diagnosed and the patient was treated successfully with nonsurgical scaling and root planing and behavioral modifications including smoking cessation and balanced nutrition intake. Disease remission was achieved after treatment. In addition, this case report reviews the effect of nutrients on the health of the periodontium.