bluuebunny/crossref_metadata_2025 huggingface dataset:
O ensino-aprendizagem e o uso de metodologias ativas da unidade temática cuidado básico à saúde da mulher do curso de enfermagem sob a ótica de monitores
Authors: Pereira Maria Alice Neves de Arruda , Santos Gabriela Fernanda dos , Silva Laryana Mayara de Lima , Silva Júlio César Bernardino da , Albuquerque Nayale Lucinda  Andrade , Melo Eduarda Augusto , Santos Raquel Bezerra dos , Sousa Vanessa Juvino de , Carvalho Maria Valéria Gorayeb de
Published: July 2022

Relatar a experiência sobre o ensino-aprendizagem e o uso de metodologias ativas da unidade temática cuidado básico à saúde da mulher do curso de Enfermagem sob a ótica de monitores. Trata-se de um relato da experiência de discentes no ensino-aprendizagem e monitoria de saúde da mulher no ciclo gravídico, puerperal e climatério, do curso de Bacharelado de Enfermagem de um Centro Universitário, localizado no Agreste Pernambucano. A vivência aconteceu entre os meses de agosto e dezembro de 2021, a qual participaram das atividades 05 docentes, 29 discentes. A primeira etapa do processo de ensino se deu a partir do embasamento teórico no ensino-aprendizagem de saúde da mulher, seguida da segunda etapa, com a construção das habilidades práticas na unidade temática. As estratégias e recursos de ensino utilizados nas aulas foram aulas expositivas dialogadas, rodas de conversa, debates em grupos e práticas em laboratório. Considera-se que o processo de ensino-aprendizagem deve ser baseado em metodologias que estimulem a criatividade, a criticidade e a autonomia dos discentes na construção das habilidade e competências. A prática de monitoria permite que os discentes-monitores aprimorem seus conhecimentos e práticas na temática, permitindo também desenvolver habilidades importantes na área da docência, além de compartilhar com os estudantes suas vivências prévias.
Síndrome metabólica e inatividade física em adultos: um estudo de casos e controles
Authors: Zanovello Syssa Reino , Iahnn Stephanie Ramirez , Freitas Glênio Alves de , Lima Rosangela da Costa
Published: July 2022

O objetivo do estudo foi avaliar a associação da síndrome metabólica com a inatividade física. Realizou-se estudo de casos-controles, aninhado a um transversal de base populacional. Adultos de 20 a 59 anos, de ambos os sexos, residentes em Dourados-MS compuseram a amostra. Os casos envolveram 149 indivíduos com três ou mais critérios: 1) pressão arterial ≥ 130 x 85 mmHg ou usando anti-hipertensivos; 2) circunferência da cintura ≥ 90 cm (homens) e ≥ 80 cm (mulheres); 3) glicemia de jejum ≥ 100 mg/dl ou usando hipoglicemiantes; 4) HDL < 40 mg/dl (homens) e < 50 mg/dl (mulheres); e 5) triglicerídeos ≥ 150 mg/dl ou usando hipolipemiantes. Os controles foram sorteados entre sujeitos que não possuíam síndrome metabólica (n = 152). A análise de dados foi realizada com os seguintes testes: Teste T, Exato de Fisher, Qui-Quadrado e Regressão Logística não condicional. Os indivíduos inativos e os em excesso de peso apresentaram aproximadamente 11 vezes mais chance de possuir síndrome metabólica do que os ativos e com peso normal. Os mais velhos mencionaram quatro vezes mais SM do que os mais novos; os homens relataram duas vezes mais SM do que as mulheres; e aqueles com menor escolaridade, duas vezes mais síndrome do que os de maior escolaridade. O estudo demonstra grande necessidade de ampliação das políticas públicas de saúde que incentivem à prática de atividade física, assim como melhorar a qualidade da alimentação da população, visando atenuar o risco de desenvolvimento da síndrome metabólica.
Perfil fermentativo, valor nutricional e microbiológico da silagem da raiz de mandioca com aditivos alimentares
Authors: Garcez Kelli Flores , Hoch Gabriela Ceratti , Rodrigues Andressa Tellechea , Schneider Cibele Regina , Soares Daniel da Costa , Castagnara Deise Dalazen
Published: July 2022

Objetivou-se caracterizar o perfil fermentativo, valor nutricional e microbiológico da silagem da raiz de mandioca in natura com e sem aditivos. Foi utilizado delineamento inteiramente casualizado em esquema de parcelas subdivididas no tempo 4x3, com cinco repetições. Nas parcelas foram alocados os materiais de estudo: Raiz de mandioca triturada in natura ou adicionado dos farelos de milho, soja ou arroz. Nas subparcelas foram alocados os tempos: material fresco: antes da ensilagem, abertura: aos 45 dias de fermentação e estabilidade após a silagem ser exposta ao ar durante sete dias. Foram realizadas as amostragens para determinação das análises bromatológicas, nutrientes digestíveis totais, digestibilidade, pH, temperatura, nitrogênio amoniacal, o perfil microbiológico por meio da determinação das populações de fungos e leveduras, Clostridium, bactérias ácido láticas e enterobactérias. A adição de farelos alterou os parâmetros avaliados. A matéria seca aumentou ao longo da fermentação e da exposição ao ar e em todos os tempos e materiais o pH foi adequado. A proteína bruta diminuiu até a abertura dos silos devido as fermentações indesejadas, apresentando-se mais elevada na silagem adicionada de farelo de soja. Os baixos conteúdos de compostos fibrosos e NDT, e a elevada digestibilidade sugerem silagens obtidas como alimentos energéticos em dietas de ruminantes e/ou monogástricos. Em conclusão, a raiz de mandioca in natura ou com inclusão de aditivos pode ser conservada na forma de silagem para uso nas dietas de ruminantes.
Enfermeiro frente a rastreabilidade automatizada do instrumental cirúrgico no Centro de Esterilização de Material
Authors: Galhardo Giselle Faria , Duarte Cássia da Conceição Melo , Saldanha Xavier Rosemere , Jesus Claudemir Santos de , Lopes Agnaldo José
Published: July 2022

Objetivo: identificar nas produções científicas a importância da rastreabilidade do instrumental cirúrgico no Centro de Material de Esterilização. Método: Este é um estudo de revisão de literatura, com abordagem qualitativa, com a seguinte questão de pesquisa: “Qual a importância da rastreabilidade do instrumental cirúrgico no Centro de Material de Esterilização?”, que permitiu a busca no ambiente online do Google Scholar, Biblioteca Virtual em Saúde nas bases da Base de Dados de Enfermagem (BDENF), Literatura Latino-americana e do Caribe em Ciências da Saúde (LILACS), e Medical Literature Analysis and Retrievel System Online (MEDLINE), no período de 2017 à 2021, com os descritores: Programas de Rastreamento; Instrumentos Cirúrgicos; Esterilização. Resultados: A busca captou 13 produções científicas, que foram analisadas e trouxeram resultados consistentes para evidenciar a qualidade do instrumental esterilizado a clientela cirúrgica. Discussão: Os estudos mostraram poucos estudos relacionados à temática, o que justifica a pesquisa, como também observou-se os benefícios nos processos de validação, segurança do paciente, cirurgia segura e até a preservação do instrumental cirúrgico. Conclusão: A importância da rastreabilidade automatizada para as boas práticas clínicas, que são importantes para uma cirurgia segura e para a segurança do paciente.
O efeito Werther e sua relação com taxas de tentativas de suicídio: uma revisão narrativa
Authors: Metelski Giuliano , Somensi Líncon Bordignon , Bonin Joel Cezar , Faustino Laurita
Published: July 2022

O suicídio é um tema complexo e muitas variáveis podem estar envolvidas no problema. Pressupõe-se que casos de tentativas de suicídio poderiam fornecer justificativas para o ato. Assim, procurou-se neste estudo encontrar indícios que apoiassem ou não a existência do efeito Werther, ou efeito contágio, na literatura científica atual. O objetivo desta revisão narrativa foi verificar se os dados disponíveis confirmavam aumento de casos de suicídio ou tentativas após um primeiro caso. Os achados indicam que o efeito é real e que está intimamente relacionado ao modo como ocorre a repercussão de um suicídio, na mídia tradicional ou por outros meios. A revisão encontrou dados que apoiam a existência do efeito contágio em várias partes do mundo, na Europa, América do Norte, e grande parte deles na Ásia, o que indica que o fenômeno não é restrito a uma dada cultura. A revisão narrativa concentrou-se em quatro bases de dados, nos últimos dez anos, nas línguas portuguesa e inglesa, e teve avaliação de dois pesquisadores.
Modelo teórico de evolução tecnológica para cultivares: um diferencial para a cobrança de royalties
Authors: Silva Eduardo José de , Silva-Mann Renata , Calazans Crislaine Costa
Published: July 2022

No Brasil, a Lei de Proteção de Cultivares ampliou as condições de apropriação por parte das instituições que pesquisam novos genótipos vegetais. A partir de então, a utilização de cultivares protegidas implica no pagamento de royalties aos seus respectivos obtentores. O presente artigo sugere um modelo teórico para auxiliar na estimativa da evolução tecnológica de cultivares e sua contribuição para a cobrança de royalties. O modelo foi formulado baseado em dados de meta-análise em que se verificou como se define a taxa dos royalties para as cultivares protegidas e como estes poderiam ser ponderados no modelo de evolução tecnológica. Definição das variáveis de acordo com a cultivar e a área de produção. Simulações analisadas para o lucro do agricultor. Verificou-se que a homoscedasticidade não foi necessária para o simples intuito da previsão de valores através do modelo de regressão. Entretanto, foi feito os teste de Breusch-Pagan e Durbin-Watson para averiguar a violação dos resíduos.  A estimativa da Evolução Tecnológica das Cultivares (algodão e cana-de-açúcar) mostrou semelhanças entre as características agronômicas de acordo com o teste de Wilcoxon. Considerando a evolução tecnológica de cada cultivar a equação de correção foi proposta aos royalties cobrados nas cultivares de algodão. A equação de correção foi proposta aos royalties cobrados nas cultivares de cana-de-açúcar. O modelo de regressão linear ratificou a utilização do modelo de correção que poderá ser usado na valoração de royalties e  que pode auxiliar na identificação da evolução tecnológica das cultivares.
A evolução do ensino em saúde no Brasil e a unidade de referência em reabilitação como cenário de prática acadêmica em terapia ocupacional: uma revisão narrativa
Authors: Souza Danielle Ferreira de , Sá Antonia Margareth Moita , Peixoto Ivonete Vieira Pereira , Pereira Ester Miranda da Silva , Sá Pedro Franco de , Corrêa Roberta de Oliveira , Rodrigues Raiza Morais , Freitas Jofre Jacob da Silva , Brito Caio Vinicius Botelho
Published: July 2022

O ensino e a assistência são elementos centrais dos cursos de graduação da área da saúde. O desafio é articulá-los de forma a contribuir com o processo de formação do aluno enquanto futuro profissional, com o compromisso de desenvolver um trabalho de qualidade, resolutivo e humanizado, sobretudo nos serviços vinculados ao Sistema Único de Saúde (SUS). O estudo apresenta aspectos sobre a evolução do ensino em saúde no Brasil e, mais especificamente, da Terapia Ocupacional, e sua relação com uma unidade de reabilitação vinculada à Universidade do Estado do Pará (UEPA), denominada Unidade de Reabilitação de Fisioterapia e Terapia Ocupacional (UEAFTO). Para isso, realizou-se uma revisão narrativa, no período de fevereiro a maio de 2022, nas bases de dados Medical Literature Analysis and Retrieval System Online (MEDLINE), Biblioteca Virtual de Saúde (BVS), Scientific Electronic Library Online (SCIELO) e Google Acadêmico, bem como leitura e análise de referências bibliográficas da disciplina “O SUS como Escola” (componente curricular do Programa de Pós-graduação Ensino em Saúde na Amazônia - Mestrado Profissional, da UEPA). A UEAFTO tem enfrentado desafios no cotidiano de seu funcionamento quanto à articulação do ensino e assistência, em conformidade com as premissas do SUS e do perfil necessário para o futuro profissional desse sistema. A Unidade é um espaço de produção de conhecimento e de cuidado à saúde, em dinâmico processo de evolução, com potencial para contribuir ainda mais com a formação de profissionais capacitados para atuação no SUS.
História da Educação Profissional no Amapá
Authors: Silva Joel Manga da , Bastos Argemiro Midonês
Published: July 2022

A História da Educação Profissional e Tecnológica (EPT) no Amapá apresenta lacunas quanto à adequação dos currículos dos cursos às normas balizadoras de criação e desenvolvimento desses currículos. Como problema de pesquisa, investigou-se: quais as bases históricas da legislação da EPT, ofertada no Amapá, desde a criação do Território Federal? Como objetivo, buscou-se compreender as bases conceituais que percorreram o currículo da EPT, para contribuir com o estudo da educação profissional amapaense. Metodologicamente, fez-se uso da pesquisa bibliográfica, documental, para traçar as normas educacionais de cada período, a história das escolas técnicas profissionais do Amapá e de seus currículos oficiais, assim como, para coletar dados de como a legislação foi posta em prática em sala de aula. A partir desta pesquisa, espera-se contribuir para ampliar o debate sobre o currículo da educação profissional no Amapá, suas ferramentas, bases conceituais, erros e acertos de cada fase histórica, legislações pertinentes para construção de um perfil curricular da educação profissional no Amapá mais adequado às necessidades e exigências locais, com suas peculiaridades e adversidades.
Dietary habits, prevalence of obesity and overweight in developed and developing countries
Authors: Lafia Aliou Toro , Ketounou Tankpinou Richard , Honfoga John Nonvignon Bossis , Bonou Semako Ibrahim , Zime Aïssatou Kora Bani
Published: July 2022

Obesity is the accumulation of excess adipose tissue that affects a person's health and physical and psychosocial well-being. The classification is based on the body mass index, which makes it possible to compare prevalence rates worldwide. Obesity and overweight have become a global epidemic in both developed and developing countries. The objective of this study is to assess the prevalence of obesity and overweight in some countries. The results showed that in the last two decades, the prevalence of obesity and overweight in the world has more than doubled. The predominance of obesity and overweight is more pronounced in Western and Westernized countries, which are more developed, than in developing countries where malnutrition and obesity coexist. This global epidemic is seen in adults, adolescents and children without exception of gender. Obesity and overweight are one of the main factors in the increase of non-communicable diseases such as cardiovascular diseases, diabetes, musculoskeletal disorders and some types of cancer in the world. Poor diet is the main cause of the growing prevalence of obesity.
Eficácia do clareamento em dentes com bráquetes ortodônticos
Authors: Schlosser Luana , Bona Vitor Schweigert , Monteiro Junior Sylvio
Published: July 2022

Objetivo: avaliar a efetividade do peróxido de hidrogênio a 38% no clareamento de dentes com aparatologia ortodôntica. Materiais e métodos: Foram confeccionados quarenta espécimes em forma de bloco de esmalte/dentina bovinos (9mm x 2mm), com 1mm de esmalte e 1mm de dentina. Após o embutimento do espécime em resina acrílica, os mesmos foram divididos em 4 grupos (n=10): Grupo 1: Controle Negativo, o espécime não recebeu nenhum tratamento; Grupo 2: Colados bráquetes ortodônticos, sem clareamento; Grupo 3: Bráquetes ortodônticos e PH38%; Grupo 4: Controle positivo, submetido ao tratamento clareador com PH38%, sem bráquetes. O agente clareador foi aplicado 1 vez por semana, por 45min, durante 4 semanas. A cor foi mensurada antes da colocação dos bráquetes e após 7 dias do clareamento pelas coordenadas L*a*b* do sistema CIE-Lab, com um espectrofotômetro. Os valores do ΔE foram analisados estatisticamente pelos testes ANOVA e Games-Howell (p<0,05). Já as coordenadas L* e a*, utilizados os testes ANOVA, T de Student’s, post hoc de Games-Howell (p<0,05); na coordenada b*, realizados os testes ANOVA, T de Student’s e post hoc de Tukey (p<0,05). Resultados: No ΔE, os grupos G3 e G4 foram estatisticamente semelhantes entre si. Já em relação as coordenadas de L* e b*, os grupos G3 e G4 apresentaram valores diferentes entre si, sendo que o G4 apontou as maiores médias; em contrapartida, a coordenada a* apresentou os maiores valores para o G3. Conclusão: clareamento com PH38% foi eficaz nos dentes com aparatologia ortodôntica.
Proceedings of the 2021 Australasian Road Safety Conference - Melbourne
Authors: Grzebieta Raphael
Published: July 2022

These proceedings describe research, educational and policing program implementation and policy and management strategies related to all aspects of road safety and especially related to the conference theme of Towards Zero: A Fresh Approach. The 2021 conference covers a comprehensive range of topics including speed, infrastructure and road design, education, licensing, vehicle design, impairment due to alcohol, drugs and mobile phones. The conference also presents innovative symposium sessions including interdisciplinary approaches combining safety, the law and design and showcasing successful programs involving at-risk youth, older drivers and safety approaches for non-occupants, specifically when we walk and ride a bicycle. Around 600 delegates from 28 countries attended the on-line virtual conference, held in this format because of COVID 19 restrictions. Authors of accepted Extended Abstracts and Full Papers represented international and local institutions from all aspects of their respective communities including research centres, private companies, government agencies and community groups. The Extended Abstracts and links to Full Papers presented in these Proceedings provide an indication of the important work being done in Australia, New Zealand and internationally as part of the United Nations, One UN Vision for Road Safety to reduce the number of crashes roads by 50 percent by 2030.
PENGARUH BURNOUT TERHADAP PRODUKTIVITAS MAHASISWA PGSD UNIVERSITAS KUNINGAN
Authors: Septiani Yeni , Triariani Meti
Published: July 2022

Dalam dunia akademik, burnout mengarah pada kondisi stress berat yang dialami oleh seseorang karena proses pembelajaran yang diikutinya terlalu monoton, serta memberikan banyak beban, sehingga dapat mengancam kesehatan fisik maupun psikisnya. Penelitian ini bertujuan untuk menguji hipotesis awal mengenai pengaruh burnout terhadap produktivitas mahasiswa PGSD diUniversitas Kuningan. Responden dalam penelitian ini terdiri dari mahasiswa PGSD di Universitas Kuningan yang berjumlah 95 orang. Penelitian ini menggunakan desain penelitian kuantitatif dengan teknik pengumpulan data berupa kuosioner yang disebarkan melalui google form. Dalam pengujiannya, penelitian ini menggunakan teknik analisis data berupa uji validitas, uji reliabilitas, serta analisis regresi yang dilakukan terhadap alat ukur untuk mengetahui hubungan antara burnout dan produktivitas mahasiswa PGSD diUniversitas Kuningan. Hasil dari uji t menunjukkan angka 0,001<0,005, hal ini membuktikan bahwa burnout memiliki pengaruh yang cukup signifikan terhadap produktivitas mahasiswa PGSD di Universitas Kuningan, yaitu sebesar 32,5%. Berdasarkan hal tersebut, maka dapat disimpulkan bahwa burnout memiliki pengaruh negatif yang menyebabkan terjadinya penurunan produktivitas mahasiswa PGSD di Universitas Kuningan. Solusi untuk mengatasi burnout dapat dilakukan dengan cara menentukan prioritas yang tepat, mengurangi ekspektasi pada diri sendiri, serta memberikan apresiasi terhadap diri sendiri.
PENGGUNAAN MEDIA TEKNOLOGI INFORMASI DAN KOMUNIKASI SELAMA PEMBELAJARAN JARAK JAUH DI KELAS RENDAH SEKOLAH DASAR
Authors: Maharani Tissa
Published: July 2022

Selama pandemi COVID 19, sistem pendidikan di Indonesia berubah. Perubahan ini  didukung Surat Edaran dari Kementrian Pendidikan dan Kebudayaan mengenai perubahan sistem pembelajaran tatap muka di kelas menjadi pembelajaran jarak jauh atau daring yang diberlakukan untuk semua tingkat pendidikan, termasuk sekolah dasar. Pembelajaran jarak jauh ini menuntut guru dan siswa memahami, menggunakan dan memanfaatkan media teknologi informasi dan komunikasi semaksimal mungkin agar dapat bertemu di dunia maya dan melaksanakan proses belajar mengajar secara efektif. Penelitian ini bertujuan untuk mengidentifikasi dan menjelaskan media teknologi informasi dan komunikasi yang digunakan selama pelaksanaan pembelajaran jarak jauh di kelas rendah sekolah dasar. Pengumpulan data penelitian ini menggunakan metode studi pustaka. Data yang digunakan adalah data sekunder yang dikumpulkan dari artikel, jurnal dan buku. Kriteria yang dipilih yaitu mengenai penggunaan dan pemanfaatan media teknologi informasi dan komunikasi di kelas rendah sekolah dasar selama pembelajaran jarak jauh atau daring. Dari  beberapa sumber yang didapatkan, kemudian dipilih yang paling relevan dan diperoleh 9 artikel. Hasil penelitian studi pustaka ini adalah media teknologi informasi dan komunikasi yang digunakan selama pembelajaran daring di kelas rendah di beberapa sekolah dasar adalah WhatsApp, YouTube, Zoom Meeting, dan audio visual (animasi).
The Impact of Audit Committee Structure on Capital Structure: A Case of Omani Listed Companies
Authors: Younas Afshan , Md Kassim Aza Azlina
Published: July 2022

Financial scandals have diverted the attention of investors, shareholders, lenders, and different stakeholders toward the corporate governance mechanism. Under the corporate governance system, the conflicts between different stakeholders are managed and controlled. Several variables work as proxies of corporate governance systems. The audit committee structure is an important tool to mitigate the adverse effects of agency problems. This study focuses on the impact of audit committee characteristics on the capital structure. The main purpose of this study is to examine the relationship between audit committee effectiveness and the leverage of the firms. Three proxies of audit committee (AC) structure are used such as AC meeting frequency, AC size, and AC independence, whereas leverage ratio is used to reflect capital structure. The study is conducted on the listed companies in the Sultanate of Oman for the period 2016 to 2019. The result of the study shows a significant negative relationship between AC meeting frequency and AC size with leverage. Whereas AC independence does not show any association with leverage in the case of Omani-listed firms. The result confirms the agency theory notion that the corporate governance system is an effective tool to balance the interest of different stakeholders and control the leverage of the firm. This study provides valuable findings to regulatory bodies and decision-makers to keep the balance capital structure through an effective audit committee structure.
How Can Martial Artists Draw Upon Pope John Paul II’s Lectures on Theology of the Body to Inform Their Practice?
Authors: Eadie Rod
Published: July 2022

Martial arts are usually relegated to the sphere of sport and often lost within the trappings of combat. In recent times, scholars have taken an interest in martial arts studies and explored how the psychosomatics of embodied practice reveals knowledge about culture and social phenomena. Commentators from within psychology, sociology, anthropology, and philosophy have spoken broadly about human connection through martial arts. However, little has been researched in theology that links spiritual teaching to the lived experience of martial arts practice. This article aims to illumine a theology that may inform the practice of martial arts. To that, I turn to Karol Wojtyla and his seminal work on Theology of the Body. I will present two key aspects; 1) that the Christian ethic may inspire fresh insights into an alternate practice of martial arts. 2) in the light of a body theology, martial arts may be viewed as a practice that supports human flourishing.
Mitigating the Digital Divide in Online Education during COVID-19: Implications for Practice and Lessons for the Future
Authors: Al Khanbashi Aadil Salim
Published: July 2022

This paper investigated the impact of the COVID-19 pandemic on education at a higher education institution (HEI). The study sample consisted of 76 teachers from an HEI in Oman. Qualitative research was used to conduct this study; document analysis was deployed to gather information from participants. The article shed light on the impact of the digital divide on learners and educators alike. Results showed that there are variations in access to devices and networks among different stakeholders. Another finding indicated by this paper was the Challenges with the technical know-how. Based on the findings, recommendations were made in an attempt to mitigate the digital divide and its negative impact on online learning in HEIs in Oman.
Spiritualitas Merti Desa dalam Pembangunan Desa Di Desa Mangunrejo Magelang Jawa Tengah
Authors: Siswayanti Novita
Published: July 2022

Spiritualitas bagi masyarakat Jawa sebagai lentera yang memberikan cahaya bagi kehidupan manusia untuk memperoleh tujuan. Spiritualitas Jawa pada tradisi Merti Desa sebagai wujud implementasi budaya Memayu hayuning bawana keseimbangan dan keharmonisan hidup secara vertikal kepada Allah dan secara horizontal kepada sesama manusia maupun lingkungannya. Penelitian ini bertujuan untuk mengetahui nilai -nilai spiritualitas dan pelestariannya dalam tradisi Merti Desa di Desa Mangunrejo Magelang.

Penelitian ini menggunakan pendekatan kualitatif deskriptif dengan metode etnografi. Adapun tahapan penelitian adalah observasi terhadap pelaksanaan tradisi Merti Desa, mewawancarai tokoh masyarakat, tokoh agama, maupun budayawan tentang Merti Desa, dan studi dokumen. Kemudian menganalisa hasil wawancara tersebut. Adapun hasil penelitiaan ini  Penelitian ini menemukan nilai spiritualitas pada Tradisi Merti Desa adalah: pertama, bersyukur kepada Allah atas karunia-Nya; kedua, karakter pemimpin ngayomi melindungi dan ngayemi menyejahterakan rakyatnya  ketiga, kebersamaan dan guyub rukun dengan adanya makan bersama; keempat, menjaga kelestarian lingkungan pertanian dengan adanya gabah dan kerambil pada pementasan wayang
Hubungan Ketuban Pecah Dini (KPD) Terhadap Persalinan Preterm: Literatur Review
Authors: Norhayati Erni , Zulliati Zulliati , Haryono Ika Avrilina
Published: August 2022

AbstrakÂ LATAR BELAKANG PrematuritasÂ  atauÂ  persalinanÂ  pretermÂ  merupakanÂ  persalinanÂ  belum cukupÂ  umurÂ  diÂ  bawahÂ  37Â  mingguÂ  atauÂ  beratÂ  bayiÂ  kurangÂ  dariÂ  2500Â  gr. Angka kejadian persalinan preterm pada umumnya adalah sekitar 6 - 10 %. Hanya 1,5 % persalinan terjadi pada umur kehamilan kurang dari 32 minggu 0,5 % pada kehamilan kurang dari 28 minggu. KPD merupakan salah faktor penyebab dari preterm.TUJUAN PenelitianÂ  iniÂ  bertujuanÂ  untukÂ  mengetahui adakah hubunganÂ  antaraÂ  ketubanÂ  pecahÂ  diniÂ  terhadapÂ  persalinanÂ  prematur.METODE Penelitian ini menggunakan pendekatan studi literatur dengan menggunakan sumber portal garuda dan google schoolar yang dipilih berdasarkan kriteria yang telah ditetapkan penulis. HASIL Dari 11 artikel yang diteliti terdapat 8 artikel yang menyatakan bahwa ketuban pecah dini (KPD) berhubungan terhadap persalinan preterm dan yang tidak berhubungan ada 3 artikel yang mana artikel tersebut membahas tentang faktor ketuban pecah dini yang lain seperti usia, paritas, pendidikan, hipertensi.KESIMPULAN Ada hubungan antara ketuban pecah dini (KPD) terhadap persalinan preterm.Â KATA KUNCI Ketuban Pecah Dini (KPD), Persalinan Preterm, Studi LiteraturÂ
Efektivitas Perawatan Payudara Menggunakan Daun Kubis Dingin Dalam Mengurangi Pembengkakan Payudara: Literatur Review
Authors: Kristin Yuni , Salmarini Desilestia Dwi , Rahmayani Dini
Published: August 2022

Latar Belakang: Masalah menyusui yang dapat timbul pada masa pasca persalinan dini (masa nifas atau laktasi) adalah pembengkakan payudara (breast engorgement) atau disebut juga bendungan ASI. Faktor resiko yang terjadinya pembengkakan payudara terkait dengan terlambatnya ibu menyusui, menyusui jarang dan pendek, maka diperlukan metode yang efektif yaitu perawatan payudara menggunakan daun kubis dingin.Tujuan: Untuk mendapatkan bukti-bukti Efektivitas perawatan payudara menggunakan daun kubis dingin dalam mengurangi pembengkakakn payudara berdasarkan literatur review.Metode:Pada penelitian ini menggunakan pendekatan studi literatur review dengan menggunakan beberapa sumber jurnal atau artikel yang dipilih berdasarkan kriteria yang telah ditetapkan. Proses pencarian dilakukan melalui elektronik based sepeti Google Scholar (5), DOAJ (2), dan Pubmed (3).Hasil: Didapatkan beberapa faktor yang menjadi penyebab terjadinya kejadian ibu mengalami pembengkakan payudara antara lain posisi menyusui, memakai bra yang terlalu ketat dan ibu nifas yang tidak menyusui bayinya seperti bayi meninggal. Â Simpulan: Dari 10 jurnal studi literatur menyatakan bahwa perawatan payudara menggunakan daun kubis dingin dalam mengurangi pembengkakak payudara dan menurunkan intensitas nyeri payudara serta peningkatan jumlah ASI.Kata kunci: Breast care ,Daun Kubis, Pembengkakan Payudara.Â AbstractIntroduction: Breastfeeding problems that can arise in the postpartum period (nifas or lactation) is breast swelling (breast engorgement) or also called breast milk dam. Risk factors for breast swelling are associated with late breastfeeding, infrequent and short breastfeeding, then an effective method of breast treatment is required using cold cabbage leaves.Aims: To obtain evidence of the effectiveness of breast care use cold cabbage leaves in reducing breast swelling based on the review literatureMethods: The study used a literature study approach using multiple sources selected based on established criteria, the researchers said. The search process is conducted through electronic-based like Google Scholar (5), DOAJ (2), and Pubmed (3).Results: There are several factors that cause the occurrence of breast swelling, among others, breastfeeding position, wearing a bra that is too tight and nifas mother who does not breastfeed her baby like a dead baby.Conclusions: Of the 10 journals of the literature study states that breast care uses cold cabbage leaves in reducing breast swelling and lowering the intensity of breast pain as well as an increase in the amount of breast milk.Keywords: Breast care, Cabbage Leaves, Breast Swelling
Where is the sow’s nose: RetinaNet object detector as a basis for monitoring the use of rack with nest-building material
Authors: Oczak Maciej , Bayer Florian , Vetter Sebastian G. , Maschat Kristina , Baumgartner Johannes
Published: August 2022

Access to nest-building material in the preparturient period is beneficial for sows’ welfare. However, on slatted floors, long-stem forage can drop into the slurry and block the drainage system. As a compromise considering the needs of sows for access to adequate nest-building material, farrowing pens with slatted floors are equipped with dispensers (racks) accessible by sows. In this study, we developed a computer vision method to monitor the use of the racks with nest-building material. In total, 12 sows were included in the experiment from 5 days before farrowing to the end of farrowing. Hay rack use behaviors were labeled for all the sows, i.e., pulling hay, nose close to the rack, exploratory behavior, and bar biting. The object detection algorithm RetinaNet was used to extract centroids of parts of the sow’s body and the hay rack. Several feature variables were estimated from the centroids of detected parts of the sow’s body, and random forest was used for the classification of hay rack use behaviors. The model for the detection of pulling hay behavior had the best performance: 83.5% sensitivity, 98.7% specificity, and 98.6% accuracy. The distance between the sows’ nose and the hay rack was the most important feature variable, which indicated the importance of nose location for the recognition of behaviors in which pigs interact with other objects. The developed models could be applied for automated monitoring of the use of nest-building material in preparturient sows. Such monitoring might be especially important in sows housed on slatted floors.
PI3K/mTOR inhibitor omipalisib prolongs cardiac repolarization along with a mild proarrhythmic outcome in the AV block dog model
Authors: van Bavel J. J. A. , Pham C. , Beekman H. D. M. , Houtman M. J. C. , Bossu A. , Sparidans R. W. , van der Heyden M. A. G. , Vos M. A.
Published: August 2022

Background

The phosphoinositide 3-kinase (PI3K) signaling pathway is an interesting target in cancer treatment. The awareness of the proarrhythmic risk of PI3K inhibitors was raised because PI3K is also involved in regulating signaling toward cardiac ion channels. Canine cardiomyocytes treated with PI3K inhibitors show an increased action potential duration and reduced cardiac repolarizing currents. Now, the potential proarrhythmic effect of chronic treatment of PI3K/mTOR inhibitor GSK2126458 (omipalisib) was investigated in the atrioventricular (AV) block dog model.

Methods

Purpose-bred Mongrel dogs received complete AV block by ablation of the bundle of His and their hearts were paced in the right ventricular apex at VDD-mode (RVA-VDD). In this way, sinus rhythm was maintained for 15 ± 1 days and thereby bradycardia-induced cardiac remodeling was prevented. Dogs received 1 mg/kg omipalisib once (n = 3) or twice (n = 10) a day via oral administration for 7 days. Under standardized conditions (anesthesia, bradycardia at 60 beats/min, and a dofetilide challenge), potential proarrhythmic effects of omipalisib were investigated.

Results

Twice daily dosing of omipalisib increased accumulative plasma levels compared to once daily dosing accompanied with adverse events. Omipalisib prolonged the QT interval at baseline and more strongly after the dofetilide challenge (490 ± 37 to 607 ± 48 ms). The arrhythmic outcome after omipalisib resulted in single ectopic beats in 30% of dogs perpetuating in multiple ectopic beats and TdP arrhythmia in 20% of dogs. Isolated ventricular cardiomyocytes from omipalisib-treated dogs showed a diminished IKs current density.

Conclusion

Chronic treatment of PI3K/mTOR inhibitor omipalisib prolonged the QT interval in a preclinical model under standardized proarrhythmic conditions. Furthermore, this study showed that electrical remodeling induced by omipalisib had a mild proarrhythmic outcome.
Left atrial acceleration factor as a magnetic resonance 4D flow measure of mean pulmonary artery wedge pressure in pulmonary hypertension
Authors: Reiter Gert , Kovacs Gabor , Reiter Clemens , Schmidt Albrecht , Fuchsjäger Michael , Olschewski Horst , Reiter Ursula
Published: August 2022

Background

Mean pulmonary artery wedge pressure (PAWP) represents a right heart catheter (RHC) surrogate measure for mean left atrial (LA) pressure and is crucial for the clinical classification of pulmonary hypertension (PH). Hypothesizing that PAWP is related to acceleration of blood throughout the LA, we investigated whether an adequately introduced LA acceleration factor derived from magnetic resonance (MR) four-dimensional (4D) flow imaging could provide an estimate of PAWP in patients with known or suspected PH.

Methods

LA 4D flow data of 62 patients with known or suspected PH who underwent RHC and near-term 1.5 T cardiac MR (ClinicalTrials.gov identifier: NCT00575692) were retrospectively analyzed. Early diastolic LA peak outflow velocity (vE) as well as systolic (vS) and early diastolic (vD) LA peak inflow velocities were determined with prototype software to calculate the LA acceleration factor (α) defined as α = vE/[(vS + vD)/2]. Correlation, regression and Bland-Altman analysis were employed to investigate the relationship between α and PAWP, α-based diagnosis of elevated PAWP (>15 mmHg) was analyzed by receiver operating characteristic curve analysis.

Results

α correlated very strongly with PAWP (r = 0.94). Standard deviation of differences between RHC-derived PAWP and PAWP estimated from linear regression model (α = 0.61 + 0.10·PAWP) was 2.0 mmHg. Employing the linear-regression-derived cut-off α = 2.10, the α-based diagnosis of elevated PAWP revealed the area under the curve 0.97 with sensitivity/specificity 93%/92%.

Conclusions

The very close relationship between the LA acceleration factor α and RHC-derived PAWP suggests α as potential non-invasive parameter for the estimation of PAWP and the distinction between pre- and post-capillary PH.
Melatonin prevents cyclophosphamide-induced primordial follicle loss by inhibiting ovarian granulosa cell apoptosis and maintaining AMH expression
Authors: Feng Juan , Ma Wen-Wen , Li Hui-Xia , Pei Xiu-Ying , Deng Shou-Long , Jia Hua , Ma Wen-Zhi
Published: August 2022

Cyclophosphaty -45mide (Cyc) chemotherapy in young female cancer patients is associated with an increased risk of premature ovarian insufficiency (POI). This study was designed to investigate the protective role of melatonin (Mel) as an adjuvant against Cyc-induced POI. Female mice received a single intraperitoneal (i.p.) dose of Cyc (75 mg/kg). Mel protection was achieved in mice after i.p. injection of melatonin (50 mg/kg) every 24 h for four consecutive days prior to chemotherapy initiation and for 14 additional days. Ovarian reserve testing, hormonal assays for follicle-stimulating hormone, luteinizing hormone, and anti-Müllerian hormone (AMH), assessment of the oxidative stress status, and measurement of the relative expression of genes in PTEN/AKT/FOXO3a and mitochondrial apoptosis pathways were performed. The results showed that treatment with 50 mg/kg Mel significantly prevented Cyc-induced over-activation of primordial follicles by maintaining the plasma level of AMH and subsequently preventing litter size reduction in mice treated with Cyc chemotherapy. Importantly, Mel treatment significantly prevented ovarian granulosa cell loss by inhibiting the mitochondrial apoptotic pathway. Identifying the protective actions of Mel against Cyc-induced primordial follicle loss has important implications for fertility maintenance in young cancer patients undergoing chemotherapy.
The effect of customer trust and commitment on customer sustainable purchasing in e-marketplace, the antecedents of customer learning value and customer purchasing value
Authors: Hongsuchon Tanaporn , Alfawaz Khaled Mofawiz , Hariguna Taqwa , Alsulami Othman Atti
Published: August 2022

The e-marketplace is a platform used by vendors to conduct transactions and shopping. The success of implementing an e-marketplace depends on customers’ sustainable purchasing. This study integrates customer learning (formative construct) and purchasing (reflective construct) values to measure the level of customer trust and commitment in the e-marketplace to examine their effects on sustainable customer purchases. A total of 428 valid respondents were processed using SmartPLS 3. The results show that the six proposed hypotheses have positive values and significant effects. Customer learning and purchasing values have positive values and significant effects on customer trust and loyalty and have indirect positive values and significant effects on sustainable customer purchases. In other words, customer trust and loyalty have positive values and significant effects on sustainable customer purchases. Thus, the findings of this study have implications for other researchers and practitioners conducting studies on e-marketplaces.
Case Report: The success of face analysis technology in extremely rare genetic diseases in Korea: Tatton–Brown–Rahman syndrome and Say–Barber –Biesecker–Young–Simpson variant of ohdo syndrome
Authors: Park Sunha , Kim Jaewon , Song Tae-Young , Jang Dae-Hyun
Published: August 2022

Tatton–Brown–Rahman syndrome (TBRS) and Say–Barber–Biesecker– Young–Simpson variant of Ohdo syndrome (SBBYSS) are extremely rare genetic disorders with less than 100 reported cases. Patients with these disorders exhibit a characteristic facial dysmorphism: TBRS is characterized by a round face, a straight and thick eyebrow, and prominent maxillary incisors, whereas SBBYSS is characterized by mask-like facies, blepharophimosis, and ptosis. The usefulness of Face2Gene as a tool for the identification of dysmorphology syndromes is discussed, because, in these patients, it suggested TBRS and SBBYSS within the top five candidate disorders. Face2Gene is useful for the diagnosis of extremely rare diseases in Korean patients, suggesting the possibility of expanding its clinical applications.
Toxoplasma effector-induced ICAM-1 expression by infected dendritic cells potentiates transmigration across polarised endothelium
Authors: Ross Emily C. , Hoeve Arne L. ten , Saeij Jeroen P. J. , Barragan Antonio
Published: August 2022

The obligate intracellular parasite Toxoplasma gondii makes use of infected leukocytes for systemic dissemination. Yet, how infection impacts the processes of leukocyte diapedesis has remained unresolved. Here, we addressed the effects of T. gondii infection on the trans-endothelial migration (TEM) of dendritic cells (DCs) across polarised brain endothelial monolayers. We report that upregulated expression of leukocyte ICAM-1 is a feature of the enhanced TEM of parasitised DCs. The secreted parasite effector GRA15 induced an elevated expression of ICAM-1 in infected DCs that was associated with enhanced cell adhesion and TEM. Consequently, gene silencing of Icam-1 in primary DCs or deletion of parasite GRA15 reduced TEM. Further, the parasite effector TgWIP, which impacts the regulation of host actin dynamics, facilitated TEM across polarised endothelium. The data highlight that the concerted action of the secreted effectors GRA15 and TgWIP modulate the leukocyte-endothelial interactions of TEM in a parasite genotype-related fashion to promote dissemination. In addition to the canonical roles of endothelial ICAM-1, this study identifies a previously unappreciated role for leukocyte ICAM-1 in infection-related TEM.
Prognosis comparison between intraoperative radiotherapy and whole-breast external beam radiotherapy for T1–2 stage breast cancer without lymph node metastasis treated with breast-conserving surgery: A case–control study after propensity score matching
Authors: Chen Qitong , Qu Limeng , He Yeqing , Xu Jiachi , Deng Yueqiong , Zhou Qin , Yi Wenjun
Published: August 2022

Background

External beam radiotherapy (EBRT), an adjuvant to breast-conserving surgery (BCS), requires a long treatment period, is costly, and is associated with numerous complications. Large sample studies with long follow-up periods are lacking regarding whether intraoperative radiotherapy (IORT), an emerging radiotherapy modality, can replace EBRT for patients with T1–2 early stage breast cancer without lymph node metastasis treated with BCS.

Methods

We identified 270,842 patients with T1-2N0M0 breast cancer from 2000 to 2018 in the Surveillance, Epidemiology, and End Results (SEER) database. A total of 10,992 patients were matched by propensity score matching (PSM). According to the radiotherapy method, the patients were divided into the IORT and EBRT groups. Overall survival (OS) and breast cancer-specific survival (BCSS) rates were analyzed and compared between the IORT and EBRT groups by Kaplan–Meier analysis. Bilateral P < 0.05 was considered to indicate significance.

Results

After PSM, the survival analysis showed no significant differences in OS or BCSS rates between the IORT and EBRT groups. In the subgroup analysis, the IORT population diagnosed from 2010 to 2013 (HRs = 0.675, 95% CI 0.467–0.976, P = 0.037) or with T2 stage (HRs = 0.449, 95% CI 0.261–0.772, P = 0.004) had better OS rates, but in the overall population, the OS and BCSS rates were better in patients with T1 stage than in patients with T2 stage (P < 0.0001), and the proportion of chemotherapy was significantly higher in T2 stage than in T1 stage. Patients who had EBRT with unknown estrogen receptor had better OS rates (HRs = 3.392, 95% CI 1.368–8.407, P = 0.008). In addition, the IORT group had better BCSS rates for married (HRs = 0.403, 95% CI 0.184–0.881, P = 0.023), grade III (HRs = 0.405, 95% CI 0.173–0.952, P = 0.038), and chemotherapy-receiving (HRs = 0.327, 95% CI 0.116–0.917, P = 0.034) patients with breast cancer compared to the EBRT group.

Conclusion

Intraoperative radiotherapy results of non-inferior OS and BCSS rates, compared to those of EBRT, in patients with early stage breast cancer without lymph node metastasis treated with BCS, and IORT may provide substantial benefits to patients as an effective alternative to standard treatment. This finding provides new insights into radiotherapy strategies for early stage breast cancer.
Evaluation of segmental scleral buckling surgery for stage 4A retinopathy of prematurity in China
Authors: Zhong Yusheng , Yang Yating , Yin Hong , Zhao Mingwei , Li Xiaoxin , Liang Jianhong , Cheng Yong
Published: August 2022

Aims

To describe the long-term effect of scleral buckling (SB) surgery for stage 4A retinopathy of prematurity (ROP).

Methods

A retrospective chart review was conducted for patients with a diagnosis of stage 4A ROP who underwent SB between October 2010 and October 2021. Basic data were collected from patient charts, including gender, birth weight, gestational age at birth, disease stage, presence of plus disease, preoperative treatment [laser photocoagulation, intravitreal anti-vascular endothelial growth factor (VEGF) agent therapy, or a combination of both] and complications (vitreous hemorrhages), postmenstrual age at surgery, intraoperative combined treatment, and total length of follow-up. Retinal attachment status after surgery, postoperative complications (glaucoma, cataract), date and type of subsequent retinal surgeries (if performed), and refractive status 1 year after surgery were evaluated. The follow-up time after the first procedure was over 1 year.

Results

Six-two eyes from forty-eight patients met the inclusion criteria for this study. The initial reattachment rate was 93.5% (58/62 eyes), and the final reattachment rate was 100% after two procedures at the end of follow-up. The incidence of cataracts was 3.2% (2/62), with no eye subsequently needing lensectomy surgery. None of the patients developed glaucoma during the follow-up time. The average spherical equivalent refraction value for patients was −3.00 ± 2.51 D (−7.60 D to +2.75 D) 1 year after surgery.

Conclusion

SB, especially segmental buckling, which induces less myopia and does not require buckle removal, has the potential to provide a significant positive impact in the treatment of stage 4A ROP.
Nitrogen and sulfur fertilizers promote the absorption of lead and cadmium with Salix integra Thunb. by increasing the bioavailability of heavy metals and regulating rhizosphere microbes
Authors: Wang Shaokun , Niu Xiaoyun , Di Dongliu , Huang Dazhuang
Published: August 2022

Fertilization is an effective agronomic strategy to improve the efficiency of phytoextraction by Salix integra Thunb. However, the specific effects of the simultaneous application of nitrogen (N) and sulfur (S) fertilizers in the rhizosphere remain unclear. We investigated the bioavailability of lead (Pb) and Cadmium (Cd) along with the microbial metabolic functions and community structure in the rhizosphere soil of S. integra after the application of N (0, 100, and 200 kg·ha−1·year−1) and S (0, 100, and 200 kg·ha−1·year−1) fertilizers for 180 days. The simultaneous application of N and S fertilizers significantly enhanced the absorption of Pb and Cd by S. integra, whereas this effect was not observed for the single application of N or S fertilizer. The contents of acid-soluble Pb and Cd in the rhizosphere soil significantly increased after either single or combined fertilize applications. The microbial metabolic activity was enhanced by the N and S fertilizers, whereas the microbial diversity markedly decreased. The metabolic patterns were mainly affected by the concentration of N fertilizer. The dominant fungi and bacteria were similar under each treatment, although the relative abundances of the dominant and special species differed. Compared to the N200S100 and N200S200 treatments, the N100S100 and N100S200 treatments resulted in fewer pathogenic fungi and more rhizosphere growth-promoting bacteria, which promoted phytoremediation by S. integra. Redundancy analysis indicated that the pH and nitrate content were the key factors affecting the structure of the microbial community. Collectively, the results suggest interactive effects between N and S fertilizers on the rhizosphere soil, providing a potential strategy for plant-microbial remediation by S. integra.