bluuebunny/crossref_metadata_2025 huggingface dataset:
Consumer perceptions and actions related to circular fashion items: Perspectives of young Brazilians on circular economy
Authors: de Aguiar Hugo Andreza , de Nadae Jeniffer , da Silva Lima Renato
Published: September 2022

The fashion industry is one of the most important industries for the world economy, but is also one of the most polluting. Some fashion companies have been adopting circular economy initiatives to combat this. Circular fashion (CF) results in cleaner production and reduces textile waste, but depends on consumer collaboration. Several studies analysing consumer CF issues worldwide have been recently published, but these studies are not common in emerging countries. This paper seeks to investigate the relationships between Brazilian consumers and CF. The methodology comprised a systematic literature review and survey. The main results show that, although young consumers are willing to change their clothing consumption habits and believe that fashion companies should be more sustainable, most of them never get involved in circular actions in the fashion chain. This paper seeks to fill a research gap on Brazilian CF, and contribute to both literature and the fashion industry in developing countries.
Treatment of refractory organics in biologically treated landfill leachate by a zero valent iron enhanced Peroxone process: Degradation efficiency and mechanism study
Authors: Bai Xue , Yang Guangxu
Published: September 2022

A zero valent iron (ZVI) enhanced Peroxone process (ZVI/Peroxone) was used to treat biologically treated landfill leachate (BTL). The treatment efficiency of the ZVI/Peroxone process was compared to single (ZVI, O3 and H2O2) and dual (ZVI/H2O2, Fe0/O3 and Peroxone) processes. The results showed that ZVI can greatly enhance the treatment capability of the Peroxone process, and the color number (CN), absorbance at 254 nm (UV254), and total organic carbon (TOC) removal efficiencies were 98.82, 84.30 and 66.38%, respectively. In the ZVI/Peroxone process, higher O3 and ZVI dosages improved organics removal, and H2O2 could promote organics removal within a certain dosage range. However, too much H2O2 decreased treatment efficiency. The best treatment performance by the ZVI/Peroxone process was obtained under acidic conditions. The three-dimensional excitation and emission matrix analysis showed that BTL mainly contained two fluorescent substances, which were fulvic-like substances in the ultraviolet region (Ex/Em = 235–255 nm/410–450 nm) and fulvic-like substances in the visible light region (Ex/Em = 310–360 nm/370–450 nm). Fluorescent substances could be substantially degraded by the ZVI/Peroxone process during the early stages of the reaction. An analysis of ZVI morphology and element valency changes showed that the micro Fe0 particles used in this study remained highly reactive during the process. The ZVI enhanced the homogenous Fenton, heterogeneous Fenton, and coagulation-flocculation effects during the Peroxone process.
Suboptimal attitude tracking control law and eigenvalue analysis for a near-space hypersonic vehicle based on Koopman operator and stable manifold method
Authors: Mi Peichao , Wu Qingxian , Wang Yuhui
Published: September 2022

This paper proposes a novel strategy to design a suboptimal attitude tracking control law for a near-space hypersonic vehicle (NSHV) based on the Koopman operator and stable manifold theory. The nonlinear vector field of the NSHV attitude model is locally Lipschitz continuous and can be approximated by a high-dimensional linear system over a compact set. Linear and nonlinear parts of the attitude dynamics are determined based on this system. Subsequently, the stable manifold theory is applied to determine the unconstrained approximated optimal control law that is used to further consider the control input constraints of the NSHV attitude model. The suboptimality of the control law is analyzed, and the local exponential stability of the closed-loop system with input constraints is proven. Furthermore, the eigenvalues for the closed-loop nonlinear attitude error dynamics are analyzed. After the control input saturation, the nonlinear closed-loop error dynamics of the NSHV can be approximated by a high-dimensional linear system with a minimal dimension. The eigenvalues of this linear system indicate the stability and time response characteristics of the attitude error dynamics of the NSHV. The numerical simulation results demonstrate the effectiveness and suboptimality of the proposed attitude tracking control law and workflow of the eigenvalue analysis.
Finite element analysis of tie wings rotation: A new phenomenon in orthodontic bracket-archwire contact assembly during simulated torque
Authors: Harikrishnan Pandurangan , Magesh Varadaraju
Published: September 2022

In orthodontics, the torque generated forces from the rectangular archwires refine the teeth position. Literature shows only linear deformation in brackets during torqueing. The objective of this study was to evaluate a new phenomenon of tie wings rotation, an angular deformation in Stainless Steel (SS) brackets with SS and Beta-Titanium (β-Ti) archwires at various angles of twist. Maxillary central incisor SS 0.457 mm × 0.635 mm and 0.558 mm × 0.711 mm brackets, SS and β-Ti archwires of 0.431 mm × 0.635 mm and 0.533 mm × 0.635 mm sizes were used. Finite element analysis was performed in various bracket-archwire assemblies for simulated torque. Palatal root torque was applied and the gingival tie wings rotation was measured at selected points, from 5° to 30° angles of twist. The tie wings rotation for 30° twist with SS 0.533 mm × 0.635 mm archwire in 0.558 mm bracket ranged from 1.32° to 2.55° and with SS 0.431 mm × 0.635 mm archwire in 0.457 mm bracket from 0.71° to 1.73°. Similarly, with β-Ti 0.533 mm × 0.635 mm archwire in 0.558 mm bracket and β-Ti 0.431 mm × 0.635 mm archwire in 0.457 mm bracket, the tie wings rotation ranged from 0.73° to 1.38° and 0.39° to 0.93° respectively. The tie wings rotation were present in all the FE models. Higher archwire size, stiffness, and angles of twist showed increased rotation. Thus, clinicians should be aware of this tie wings rotation during torqueing as an additional factor for torque loss.
Antidiabetic effects of nerolidol through promoting insulin receptor signaling in high-fat diet and low dose streptozotocin-induced type 2 diabetic rats
Authors: Jiang Nengmei , Zhang Yuanyuan
Published: September 2022

The present study was designed to investigate the antidiabetic effect of nerolidol on high-fat diet and streptozotocin-induced diabetic rats. Type 2 diabetes was induced in animals by feeding them a high-fat diet for 4 weeks and administering a single intraperitoneal dose of streptozotocin (35 mg/kg body weight). Diabetic rats were treated with nerolidol (25 mg/kg BW) for 28 days. Results showed that nerolidol treatment significantly reduced ( p < 0.05) the level of elevated glucose, glycosylated hemoglobin and improved ( p < 0.05) the body weight and insulin level. Nerolidol also considerably improved ( p < 0.05) the carbohydrate metabolic enzyme activities and increased the glycogen storage in the liver of diabetic rats. Increased serum triglycerides, total cholesterol (C), low-density lipoproteins-C and very low-density lipoproteins-C levels were significantly lowered ( p < 0.05), while reduction of serum high-density lipoprotein-C was alleviated after administration of nerolidol. In addition, nerolidol attenuated oxidative stress markers by significantly increasing ( p < 0.05) the levels of superoxide dismutase, catalase, reduced glutathione, and lowering ( p < 0.05) the level of thiobarbituric acid reactive substances, and lipid hydroperoxide. Similarly, nerolidol showed its pharmacological effects against hepatic markers via restoring ( p < 0.05) the alleviated level of alanine transaminase, aspartate aminotransferase, and alkaline phosphatase. Finally, it improved insulin-dependent glucose transport in skeletal muscle by enhancing and activating glucose transporter protein-4. These findings confirmed the antidiabetic potential of nerolidol in type 2 diabetic rats. This may be related to a high antioxidant capacity, the restoration of plasma insulin and lipid levels, and the activation of insulin signaling in STZ/HFD-induced diabetic rats.
The effects of drilling parameters on thrust force, temperature and hole quality of glass fiber reinforced polymer composites
Authors: Malik Khurshid , Ahmad Faiz , Keong Woo Tze , Gunister Ebru
Published: September 2022

This paper presents an investigation of the drilling performance of glass fiber reinforced polymer (GFRP) composite based on the thrust force, temperature, and delamination factor (at entry and exit of the hole). High-speed steel (HSS), solid carbide (SC), and solid carbide Balinit® Helica coated (SCBH) twist tools were used for the drilling process. Other drilling parameters were high spindle speeds (12,000, 15,000, and 18,000 rpm), feed rate (300, 500, and 700 mm/min), and laminate thickness (3, 5, and 7 mm). ANOVA and response surface methodology were developed to examine the drilling process based on input and output parameters. Results showed that delamination was observed in the form of matrix debonding, uncut fibers, and fiber pull-out. The best drilling performance was achieved by the SC and SCBH tool at a low feed rate (300 rpm) and high speed (18,000 rpm), and high laminate thickness (7 mm).
Dyad Gender and Relationship Quality Influence Heart Failure Self-Care
Authors: Stawnychy Michael A. , Vellone Ercole , Zeffiro Valentina , Teitelman Anne M. , Maria Maddalena De , Riegel Barbara
Published: September 2022

Caregivers promote heart failure self-care, yet little is known about how relationship quality and dyad gender influences self-care. The purpose of this study was to evauluate the contribution of dyad gender and relationship quality on heart failure self-care. The study was a secondary analysis from a heart failure self-care intervention. Dyad gender was categorized by patient-caregiver gender as Male-Male (M + M), Female-Female (F + F), Female-Male (Fp + Mc), and Male-Female (Mp + Fc). The Self-Care of Heart Failure Index v.6.2 measured self-care. The Mutuality Scale assessed relationship quality. Univariate linear regression identified determinants of patient self-care maintenance and self-efficacy. The sample ( n = 503) was 48% Mp + Fc, 27% F + F, 15% Fp + Mc, and 10% M + M. Better caregiver mutuality in M + M dyads was associated with lower self-care maintenance ( b = −7.45, 95% CI [−13.80, −1.11]) and self-efficacy ( b = −18.07, 95% CI [−29.11, −7.04]). Better patient mutuality was associated with higher self-efficacy for M + M dyads ( b = 12.63, 95% CI [2.18, 23.09]). Mutuality and dyad gender appear important for self-care. Consider the role of gender in the dyad in behavioral interventions.
Choosing a Multidisciplinary Cleft and Craniofacial Team: Medical, Surgical, and Social Considerations
Authors: Villavisanis Dillan F. , Blum Jessica D. , Plana Natalie M. , Taub Peter J. , Taylor Jesse A.
Published: September 2022

Cleft and craniofacial conditions often present with a variety of functional and esthetic sequelae optimally treated by a multidisciplinary approach. Diagnosis of such conditions pre- or postnatally may evoke parental uncertainty and anxiety, and an important primary consideration is the selection of a cleft and craniofacial team. Identifying an optimal team may be particularly important for developing long-term relationships with clinicians who will ideally work intimately with the family from diagnosis to adulthood. While families, parents, and providers should consider several factors, a dearth of evidence-based suggestions preclude critical appraisal of cleft and craniofacial teams. In this article, the authors summarize medical, surgical, and social considerations for selecting a cleft and craniofacial team to optimize patient outcomes and the family/caregiver experience.
Does Our Employee Assistance Program Cover Voodoo Dolls? A Cry for Help on Behalf of Those Affected by Abusive Supervision
Authors: Haggard Dana L. , Priya Kanu
Published: September 2022

Consistent with the goals of a GOMusing to “refresh” readers’ minds about a topic, challenge readers to re-examine their assumptions about a topic, and/or spark a needed debate about a topic, we (1) provide a refresher on abusive supervision and the severity of its consequences, (2) acknowledge the wealth of research on its antecedents and moderators while highlighting the lack of applied research on successful interventions, and (3) encourage new research perspectives and methods to move the field forward. Our ultimate goal is to galvanize scholars to use existing knowledge as a basis to develop, test, and validate successful prevention and intervention strategies for organizations and individuals to deal with abusive supervision. As you might suspect from the title, we also hope to do all this with a bit of humor and a lot of compassion.
Community Members as Fieldwork Guides in Disaster Settings: Ethics of Care Through a Relational Methodology of Empathy and Trust
Authors: Hakkim Adeeba
Published: September 2022

This reflexive account of fieldwork with disaster-affected communities in Kerala, India, recounts the researcher’s engagement with positionality and ethics. A participatory method was adopted—enlisting local field guides who mediated the researcher’s interactions with participants. Apart from offering pragmatic solutions for accessing participants, the method enhanced the researcher’s contextual/cultural insight, and facilitated a relationship of trust. The researcher-guide dynamic is explored as a co-constructing and relational method that minimizes harm and maximizes benefit for participants. Ethics of care is elucidated as a practicable ethical framework for thinking and doing disaster research, illustrated with reference to the present method.
Inequity Reduction in Road Maintenance Funding for Municipalities
Authors: Bonilla Minerva , Rasdorf William , Liu Min , Al-Ghandour Majed , He Chuanni
Published: September 2022

State transportation agencies distribute funding to eligible municipalities to maintain local roads in a safe condition based on their permanent population and street mileage. However, some municipalities experience an exceedingly high seasonal population that is unaccounted for and thus, they are not receiving equitable funding. To better understand seasonal population and mitigate its impact, this paper evaluates equity and affordability in funding allocation, explores how to estimate seasonal population, suggests a method to improve the current allocation, and identifies practical strategies to reduce disproportionate funding distribution. Three funding allocation strategies were developed and a need-based funding allocation approach was identified to be an equitable solution to help municipalities improve local street conditions based on their needs while subject to constraints on funding availability. This approach allows municipalities to address seasonal population increases without negatively impacting funds for municipalities that do not experience fluctuations in their population.
“How Should the Police Let Victims Down?” The Impact of Reassurance Call-Backs by Local Police Officers to Victims of Vehicle and Cycle Crimes: A Block Randomized Controlled Trial
Authors: Clark Ben , Ariel Barak , Harinam Vincent
Published: September 2022

Most victims’ cases are not progressed through the criminal justice system, which is a phenomenon linked to low satisfaction with police performance. Little is known about how police can fairly and effectively “let victims down.” One mechanism is a call-back, which is prevalent in other professions but less so in policing and could be applied specifically for victims who experience case attrition at early stages. By proactively contacting victims following their initial report, the call-back may offer reassurance and lead to improved levels of satisfaction. We tested this approach with 1326 victims of vehicle and bicycle crimes in a block randomized controlled trial in London, UK. Based on follow-up telephone surveys, the findings suggest that a reassurance call-back policy increases the satisfaction of bicycle theft victims by 5%–15%, but not for victims of vehicle theft, who are largely unaffected by the call-back. The findings are likely driven by the victims’ expectations: vehicle theft victims expect their reported cases to progress through the justice system, whereas bicycle theft victims do not; thus, the former remain as disappointed as the participants who did not receive a call-back. These findings are promising, as they offer a new tool for policing that can provide more care to victims of crime.
Evidence-Based User Interface Sanitation Technology Selection for Urban Slums: A Multi-Criteria Analysis; The Case of Jimma Town, Ethiopia
Authors: Donacho Dereje Oljira , Tucho Gudina Terefe , Zeine Ousman Wuhib , Both Thanyang Koang , Hailu Abebe Beyene
Published: September 2022

Slums are urban areas with insufficient public services and access to sanitation. Evidence-based selection of sustainable sanitation options is critical for addressing the sanitation crisis in slums. This mixed methods study was conducted in Jimma Town, southwest Ethiopia, to assess sanitation status and prioritize sustainable sanitation options for slums. The study was done in 2 phases: quantitative and qualitative. The quantitative cross-sectional household survey aimed to assess sanitation status and the qualitative exploratory method to explore alternative sanitation options and prioritize sustainable alternatives. A total of 310 households were chosen using systematic random sampling methods, of which 302 participated. Data was gathered through interviews, which were supplemented with questionnaires and observation checklists, and 2 focus group discussions (FGD) were held. First, FGD was with expertise in the sanitation sector, and the second was with community members. The state of sanitation was summarized, and multi-criteria analysis (MCA) was used to prioritize sustainable sanitation options. According to our findings, 68% of households had access to improved facilities, and 22.5% didn’t have any form of toilet facility. About 7 off-site and on-site user interface sanitation technology options were considered in the selection of alternative sanitation technologies, and each option was evaluated against 17 health, economic, social, technical, and environmental criteria. In the final analysis, the options with the highest scores for the setting were flush to septic tanks, compost toilets, and biogas toilets. Mobilizing such a promising sanitation option is recommended for future interventions.
Prognostic Values From Integrated Analysis of the Nomogram Based on RNA-Binding Proteins and Clinical Factors in Endometrial Cancer
Authors: Yuan Shuang , Sun Xiao , Wang Lihua
Published: September 2022

Background:

Endometrial cancer (EC) is a common gynecological malignancy, and the prognosis of advanced EC is unsatisfactory. The deregulated expression of RNA-binding proteins (RBPs) is closely associated with the occurrence and development of cancer. However, the role of RBPs in EC remains unclear. The aim of this study was to validate the prognostic values of RBPs combined with clinical factors.

Methods:

We downloaded the RNA sequencing and clinical data for EC from The Cancer Genome Atlas (TCGA) database. R software was used to identify the differentially expressed RBPs. Univariate and multivariate Cox proportional hazards regression analyses were performed to predict the 4 overall survival (OS)-related RBPs. We then constructed a nomogram combining the 4-RBP signature with clinical risk factors to assess the prognostic power. Furthermore, we validated the expression of 4 RBPs in our patient samples using quantitative real-time polymerase chain reaction (qRT-PCR) and explored the effect of cold-inducible RNA-binding protein (CIRBP) on EC tumor growth using cell proliferation experiments.

Results:

It is found that Shwachman-Bodian-Diamond syndrome (SBDS), CIRBP, MRPL15, and CELF4 were significantly related to the prognosis of EC patients. In addition, the nomogram showed better performance in OS predictions than the International Federation of Gynecology and Obstetrics (FIGO) stage. The qRT-PCR results showed that low CIRBP expression was associated with cell proliferation.

Conclusions:

In our study, we constructed a 4-RBP signature-based nomogram combined with clinical factors in EC that could effectively predict the prognosis of EC patients. The results provide novel insights into the development of treatment targets and prognostic molecular markers in EC.
Nurturing patriotism and national pride: An ethnographic exploration into the everyday worlds of Yekolo temari in Washera Qenie School
Authors: Kassa Taglo
Published: September 2022

Anchored in an ethnographic fieldwork in rural Ethiopia, involving 66 children (12–18 years old) and 17 church scholars, this article looks at how a traditional school of the Ethiopian Orthodox Church nurtures sentiments of patriotism and national pride in Yekolo temari (children in the school). The findings revealed a multitude of pedagogical approaches that the church school employed. The school system also provided the students with ample cultural resources that enhance their national pride and patriotic feeling. This research has practical implications and contributes to the literature on national identity (re)construction, specifically on ways of cultivating patriotism and national pride among schoolchildren.
Erotic capabilities: A feminist analysis of sexual justice and pleasure in heterosexual sex partying
Authors: Tsui Pamela P
Published: September 2022

In gender and sexuality studies, heterosexual sex has often been portrayed in terms of inequality and injustice; however, there has been scant discussion of what social conditions may cultivate a democratic and egalitarian culture that sustains sexual autonomy. Developed from Nussbaum’s capabilities approach, I propose the erotic capabilities approach to assess and promote entitlement to erotic choices and erotic freedoms in everyday practice. I argue that erotic capabilities should consist of the following: (1) freedom from sexual coercion and deprivation; (2) democratized sexual knowledge; (3) sexual health options; (4) inclusive space for diversified erotic expressions; (5) erotic affiliation and negotiation; and (6) diversified erotic aspirations, fulfilments and experimentations. Drawing on a 29-month ethnography of a sex party club in Hong Kong, I demonstrate how the erotic capabilities approach can be used in a meso-level analysis to evaluate a sexual space or community which, while situated in the overarching patriarchal ideology, may or may not offer a reflexive space for its participants to define their erotic selves. As this study formulates sexuality as a vehicle of empowerment that can and should be cultivated and actualized, it illuminates the possibility to imagine and create agentic and pleasurable opportunities for people in different social locations under the patriarchy we still live in.
Moral experiences of children with medical complexity: A participatory hermeneutic ethnography in Brazil
Authors: Passos dos Santos Raíssa , Macdonald Mary Ellen , Carnevale Franco A
Published: September 2022

Children with medical complexity have been defined within the literature as chronically ill and medically fragile children with complex care needs. Care for these children raises significant ethical and moral considerations. Therefore, this participatory ethnographic study conducted with eight children and their families aimed to better understand the moral experiences of children with medical complexity, based on views of children as moral agents and capable of understanding and expressing interpretations about their lived experiences. Through our participatory hermeneutical ethnographic research, we were able to shed light on how children with medical complexity express their moral experiences within a complex sociopolitical context, perpetuating dominant outlooks on what is considered a “normal” child. Children with medical complexity described their resistance to these dominant views as they strive to be included in discussions about matters that affect them, reacting to painful medical procedures and treatments, and expressing their concerns about their future aspirations. The knowledge advanced by this study about moral experiences of children with medical complexity can inform understandings of children’s interests based on their own interpretations within complex sociopolitical contexts that value their lives differently.
The fatigue fracture mechanism of Al7075 aluminum alloy clinching joints
Authors: Zhang Yue , Lu Yan , Peng Ruitao , Xu Honghe , Zhu Linwei , Wang Tao
Published: September 2022

Lightweight aluminum alloys are widely used in automotive structural parts. Clinching (press-joining) is one of the most promising alternatives to welding for joining aluminum alloys, and as the failure of the joint is mainly caused by fatigue, the fatigue properties of the clinched joints directly affect the reliability and safety of the connected specimens. To gain a deeper understanding of this phenomenon, the static mechanical and fatigue properties of Al7075 aluminum alloy single-lap clinched joints were studied using static strength and tensile-tensile fatigue tests. The F–N curves of the joints were fitted using a straight-line and three-parameter power function method. The fractured samples and wear scars were analyzed by scanning electron microscopy and energy-dispersive spectroscopy. The results showed that the neck of the clinched joint and the upper sheet near the joint experienced the highest degree of fatigue fracture, the fretting wear debris consisted mainly of alumina and metallic aluminum, and the fretting wear was of a mode that differed from the two modes identified in the literature that we have dubbed “upper sheet inter-sheet region fretting wear.”
The Choice of Osteosynthesis for Distal Radius Fractures: A Matter of Taste, Fracture Instability, or Patient-Related Factors? A Retrospective Study of Functional Outcome in 346 Distal Radius Fractures Operated With Percutaneous Wires or Volar Plate Fixation
Authors: Holmqvist Karl-Johan , Johnson Ted , Fornander Lotta
Published: September 2022

Background:

Surgery with volar locking plate (VLP) for distal radius fractures (DRFs) has become dominant over percutaneous Kirschner wire (K-wire) (PKW) fixation. Not many studies have proved advantages of the VLP and the increasing dominance of the VLP is thus not derived from evidence of superiority but influenced by other factors.

Methods:

By retrospectively classifying 346 DRFs treated with either PKW or VLP fixation, according to the Buttazzoni classification system, we aimed to investigate the determining factors for choice of surgical method, and by review of the patients’ medical records, the functional outcome, duration, and frequentness of the rehabilitation period were correlated to Buttazzoni type and surgical method.

Results:

The odds ratio of having volar plate fixation was negatively correlated to age and positively correlated to a higher Buttazzoni type. We found no clinically significant differences in the functional outcome for different Buttazzoni type of fractures within the VLP and PKW groups, respectively, nor between the 2 methods of surgery for any Buttazzoni type of fracture.

Conclusion:

Younger patients and fractures with higher grade of instability were more likely to be treated with VLP than PKW; however, neither fracture instability nor surgical method had any impact on functional outcome.
Complications Following Ulnar Artery Catheterization for Coronary Angiography
Authors: Grasso Mackenzie B. , McLaughlin Jillian , Amendola Michael F. , Cotterell Ilvy H. F.
Published: September 2022

Background:

Use of radial and ulnar access has increased due to its perceived benefits over femoral access. Ulnar artery catheterization can place patients at risk of significant complications, including pseudoaneurysm, expanding hematoma, compartment syndrome, ulnar nerve injury, and critical hand ischemia. The purpose of this study was to describe complications specific to ulnar artery catheterization.

Methods:

After obtaining institutional review board approval, a retrospective review was performed on all patients who underwent ulnar artery catheterization at our institution between 2019 and 2021. Complications were assessed, and complication rates were compared with previously published studies on ulnar artery catheterization for coronary angiography (percutaneous coronary intervention).

Results:

A total of 41 patients were available for review with a mean age of 59 years. Of these, 17 patients (41%) sustained complications in the immediate postprocedural period. These complications included hematoma (12 patients, 29%), pseudoaneurysm (1 patient, 2%), ulnar artery thrombosis (1 patient, 2%), ulnar neuropathy (3 patients, 7%), arterial damage requiring repair (2 patients, 5%), transient ischemia (3 patients, 7%), and compartment syndrome (2 patients, 5%). Three of these patients (7%) required operative intervention, and several were admitted to the hospital for an additional period of observation.

Conclusions:

This series highlights the significant risks associated with ulnar artery catheterization for percutaneous procedures. Complications include pseudoaneurysm, expanding hematoma, compartment syndrome, ulnar nerve damage, and critical hand ischemia. Several of these patients required urgent or emergent surgical intervention, with some patients experiencing ongoing ulnar nerve symptoms.
Patient and Provider Prediabetes Knowledge, Attitudes, and Behaviors in a Large Urban Family Medicine Practice
Authors: Li Erica , Waters Alexa , Cunningham Amy , Silverio Alexis , Han Jasmine , Mills Geoffrey
Published: September 2022

One-third of U.S. adults have prediabetes, but only 11% are aware of their condition. Many do not receive education or treatment. The purpose of this study is to understand family medicine providers’ and patients’ attitudes, knowledge, and behaviors regarding prediabetes and its management, to guide future management interventions. Cross-sectional surveys of providers ( n = 54, 57% response rate) and patients with prediabetes ( n = 148, 16.5% response rate) were administered at a large urban academic family medicine practice. Nearly all providers agree prediabetes screening is important, but over half were unaware of the national Diabetes Prevention Program (DPP) and most do not prescribe metformin to eligible patients. Over half of patients reported being told they have prediabetes but <5% had been referred to DPP and over half were unaware of medication options. In open-ended responses, providers suggested nutrition counseling resources and an improved DPP referral process to improve prediabetes care. Patients requested clear diagnosis, education on treatment options, and nutritional counseling. This study indicates that notable gaps continue to exist in provider and patient understanding and management of prediabetes, suggesting that interventions to improve prediabetes care should include more effective counseling on diagnosis and treatment and expanding access to nutrition and educational resources.
Electronic common technical document submission with analysis using R
Authors: Zhao Yujie , Xiao Nan , Anderson Keaven , Zhang Yilong
Published: September 2022

Background:

In clinical trial development, it is a critical step to submit applications, amendments, supplements, and reports on medicinal products to regulatory agencies. The electronic common technical document is the standard format to enable worldwide regulatory submission. There is a growing trend of using R for clinical trial analysis and reporting as part of regulatory submissions, where R functions, analysis scripts, analysis results, and all proprietary code dependencies are required to be included. One unmet and significant gap is the lack of tools, guidance, and publicly available examples to prepare submission R programs following the electronic common technical document specification.

Methods:

We introduce a simple and sufficient R package, pkglite, to convert analysis scripts and associated proprietary dependency R packages into a compact, text-based file, which makes the submission document self-contained, easy to restore, transfer, review, and submit following the electronic common technical document specification and regulatory guidelines (e.g. the study data technical conformance guide from the US Food and Drug Administration). The pkglite R package is published on Comprehensive R Archive Network and developed on GitHub.

Results:

As a tool, pkglite can pack and unpack multiple R packages with their dependencies to facilitate the reproduction and make it an off-the-shelf tool for both sponsors and reviewers. As a grammar, pkglite provides an explicit trace of the packing scope using the concept of file specifications. As a standard, pkglite offers an open file format to represent and exchange R packages as a text file. We use a mock-up example to demonstrate the workflow of using pkglite to prepare submission programs following the electronic common technical document specification.

Conclusion:

pkglite and the proposed workflow enable the sponsor to submit well-organized R scripts following the electronic common technical document specification. The workflow has been used in the first publicly available R-based submission to the US Food and Drug Administration by the R Consortium R submission working group ( https://www.r-consortium.org/blog/2022/03/16/update-successful-r-based-test-package-submitted-to-fda ).
A New Look at Young Children’s Referential Informativeness
Authors: Vasil Jared
Published: September 2022

In this article, I review experimental evidence for the dependence of 2- to 5-year-olds’ linguistic referential informativeness on cues to common ground (CG) and propose a process model. Cues to CG provide evidence for CG, that is, for the shared knowledge, beliefs, and attitudes of interlocutors. The presence of cues to CG (e.g., unimpeded listener line of regard or prior mention) is shown to be associated with less informative reference (e.g., pronouns). In contrast, the absence of cues to CG (e.g., impeded listener line of regard or new mention) is shown to be associated with more informative reference (e.g., nouns). Informativeness is sensitive to linguistic before nonlinguistic cues to CG (i.e., 2.0 vs. 2.5 years old, respectively). Reference is cast as a process of active inference, a formulation of Bayesian belief-guided control in biological systems. Child speakers are hierarchical generative models that, characteristically, expect sensory evidence for the evolved, prior Bayesian belief that interlocutor mental states are aligned (i.e., that CG exists). Referential control emerges as an embodied tool to gather evidence for this prior belief. Bottom-up cues to CG elicited by action drive updates to beliefs about CG. In turn, beliefs about CG guide efficient referential control.
Lack of bump in public events when recent events prevail
Authors: Öner Sezin , Gülgöz Sami
Published: September 2022

Reminiscence bump refers to the increased recall of events from adolescence and early adulthood. It is a robust phenomenon for personal events, while the evidence for the bump has been inconsistent for public events. The present study addressed lifespan distributions of public events in a nationally representative sample of adults ( N = 1200) in Turkey. We demonstrated a robust recency effect in the temporal distribution of public event memories. When we examined the bump in the most frequently reported events, the recency effect persisted. The only exception was the bump for the military coup in 1980, a relatively more distant event among the most frequent events. Findings suggested that high-impact events in Turkey’s recent past may overshadow the past events. Inline, we discuss the role of the context and age distribution of the sample to explain the inconsistency in the evidence for the reminiscence bump in public events.
The key features of workplace meetings: Conceptualizing the why, how, and what of meetings at work
Authors: Allen Joseph A. , Lehmann-Willenbrock Nale
Published: September 2022

Given the focal role that group and team meetings play in shaping employees’ work lives (and schedules), the scarcity of conceptual and empirical attention to the topic in extant organizational psychology research is a major oversight that stalls scientific understanding of organizational behavior more broadly. With the explosion of meetings in recent years, in part due to the COVID-19 pandemic, some even wonder why organizational psychology has not already figured out meetings from both a science and practice perspective. The purpose of this paper is to synthesize the extant literature on the science of workplace meetings and sort the works by identifying the key features of the meeting phenomenon. The five key features of workplace meetings identified include Leading, Interacting, Managing Time, Engaging, and Relating. We couch these features within a larger framework of how meetings are the intersection of collaboration in organizations and indispensable to organizational success. Against this conceptual backdrop, we reviewed a total of 253 publications, noting opportunities for future research and discussing practical implications.
Root Causes of Migration, Development, and US Aid to Northern Triangle States
Authors: Gerschutz-Bell Jill Marie
Published: September 2022

For decades, governments have sought to deter migration by investing in the development of migrant-sending communities, despite macroeconomic data that shows that development can increase emigration. However, emerging research suggests that well-designed aid can promote rootedness in home communities. The US Agency for International Development (USAID) has increasingly attempted to use development to deter migration from the Northern Triangle states of Central America. Is this policy sound?

This paper argues that development should not be instrumentalized to discourage people from migrating. It examines migration and development policies from the lens of Catholic social teaching, which recognizes the need for states to respect the agency of individuals. This is particularly important when it comes to complex and consequential decisions like whether to migrate. The Catholic Church recognizes both a right to migrate, when necessary, and the responsibility of states, particularly wealthy nations, to help people realize the right not to migrate; that is, to thrive in their home communities. The paper argues for US government assistance to alleviate poverty and invest in human capital in Central America, but independently of efforts to deter migration. Prioritizing aid to potential migrants risks reducing its effectiveness. The United States should instead pursue a whole-of-government strategy that emphasizes the right relationships with aid recipients, and that prioritizes and empowers the poor and marginalized. The paper is strongly influenced by the author's 15 years of work for Catholic agencies on migration and development, more than one-half of those with Catholic Relief Services.
Signaled or Suppressed? How Gender Informs Women’s Undergraduate Applications in Biology and Engineering
Authors: Giebel Sonia , Alvero AJ , Gebre-Medhin Ben , Antonio Anthony Lising
Published: September 2022

How does gender inform initial academic commitments and narrative self-presentation in science, technology, engineering, and mathematics (STEM) fields during the college application process? Analyzing 60,000 undergraduate applications to the University of California, the authors surface two key findings. First, extant gender segregation of academic disciplines also manifests in intended major choice. Additionally, gender and SAT Math scores together strongly predict intent to major in biology and engineering, the most popular and gender-segregated majors. Second, using natural language processing, the investigators find that author gender is more predictive of essay topics written by prospective engineers than prospective biologists. Specifically, women intending to major in engineering write about essay topics that signal their gender identity to a greater degree than women intending to major in biology, perhaps to mitigate gender-transgressive academic commitments. The authors subsequently argue that prescriptive and proscriptive ideas about men and women’s academic choices remain highly salient in a moment of imagining future academic and professional selves.
Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data
Authors: Mai Hung , Bao Jingxuan , Thompson Paul M. , Kim Dokyoon , Shen Li
Published: September 2022

Background

Brain volume has been widely studied in the neuroimaging field, since it is an important and heritable trait associated with brain development, aging and various neurological and psychiatric disorders. Genome-wide association studies (GWAS) have successfully identified numerous associations between genetic variants such as single nucleotide polymorphisms and complex traits like brain volume. However, it is unclear how these genetic variations influence regional gene expression levels, which may subsequently lead to phenotypic changes. S-PrediXcan is a tissue-specific transcriptomic data analysis method that can be applied to bridge this gap. In this work, we perform an S-PrediXcan analysis on GWAS summary data from two large imaging genetics initiatives, the UK Biobank and Enhancing Neuroimaging Genetics through Meta Analysis, to identify tissue-specific transcriptomic effects on two closely related brain volume measures: total brain volume (TBV) and intracranial volume (ICV).

Results

As a result of the analysis, we identified 10 genes that are highly associated with both TBV and ICV. Nine out of 10 genes were found to be associated with TBV in another study using a different gene-based association analysis. Moreover, most of our discovered genes were also found to be correlated with multiple cognitive and behavioral traits. Further analyses revealed the protein–protein interactions, associated molecular pathways and biological functions that offer insight into how these genes function and interact with others.

Conclusions

These results confirm that S-PrediXcan can identify genes with tissue-specific transcriptomic effects on complex traits. The analysis also suggested novel genes whose expression levels are related to brain volumetric traits. This provides important insights into the genetic mechanisms of the human brain.
Lactase bacteria in intestinal mucosa are associated with diarrhea caused by high-fat and high-protein diet
Authors: Zhou Kang , Peng Maijiao , Deng Na , Tan Zhoujin , Xiao Nenqun
Published: September 2022

Background

Excessive fat and protein in food can cause diarrhea by disturbing the intestinal microecology. Lactase is a functional enzyme strongly associated with diarrhea, while lactase bacteria in the intestine are an important source of microbial lactase. Therefore, we reconnoiter the relationship between diarrhea induced by a high-fat and high-protein diet (HFHPD) and intestinal mucosal lactase bacteria from the perspective of functional genes.

Result

Operational Taxonomic Units (OTUs) were 23 and 31 in the normal group (NM) and model group (MD), respectively, and 11 of these were identical. The Chao1 and Observed specie indexes in the MD were higher than those in the NM, but this was not significant (P > 0.05). Meanwhile, the Principal coordinate analysis (PCoA) and Adonis test showed that the community structures of lactase bacteria in NM and MD were significantly different (P < 0.05). In taxonomic composition, lactase bacteria on the intestinal mucosa were sourced from Actinobacteria and Proteobacteria. Where Actinobacteria were higher in NM, and Proteobacteria were higher in MD. At the genus level, Bifidobacterium was the dominant genus (over 90% of the total). Compared to NM, the abundance of Bifidobacterium were lower in MD, while MD added sources for lactase bacteria of Rhizobium, Amycolatopsis, and Cedecea.

Conclusions

Our data demonstrate that HFHPD altered the community structure of lactase bacteria in the intestinal mucosa, decreased the abundance of the critical lactase bacteria, and promoted the occurrence of diarrhea.
Levels of depressive symptoms in cardiac patients attending cardiac rehabilitation with a history of depression: pre Covid-19 and Covid-19 period comparison
Authors: Sever Serdar , Harrison Alexander Stephen , Doherty Patrick
Published: September 2022

Background

The large-scale changes in cardiac rehabilitation (CR) programme delivery in response to COVID-19 has led to diminished provision. The influence of these service changes on the depression symptoms of patients in CR programmes is unknown. Our study investigated the extent of depressive symptoms prior to and during the COVID-19 periods in patients with a previous history of depression at the start of CR.

Methods

Use of Registry routine practice data, National Audit of Cardiac Rehabilitation (NACR), from COVID-19 period Feb 2020 and Jan 2021, as well as pre COVID-19 period Feb 2019 and Jan 2020, was extracted. Depressive symptoms were defined according to Hospital Anxiety and Depression Score ≥ 8. Chi-square tests and independent samples t-tests were used to investigate baseline characteristics. Additionally, a binary logistic regression to examine the factors associated with high levels of depressive symptoms.

Results

In total 3661 patients with a history of depression were included in the analysis. Patients attending CR during COVID-19 were found to be 11% more likely to have high levels of acute depressive symptoms compared to patients attending CR prior to COVID-19. Physical inactivity, increased anxiety, a higher total number of comorbidities, increased weight, and living in the most deprived areas were statistically significant factors associated with high levels of acute depressive symptoms at the start of CR following multivariate adjustments.

Conclusion

Our research suggests that following a cardiac event patients with prior history of depression have high levels of acute depressive symptoms at CR baseline assessment. This finding exists in both the pre Covid-19 and Covid-19 periods in patients with a history of depression.