bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficacy of Continuous Care Model Implementation on Body Mass Index and Lifestyle of Middle-aged Obese People
Authors:   Clinical Research Development Unit, Bohlool Hospital, Gonabad University of Medical Sciences, Gonabad, Iran., Tavakolizadeh Mitra , Moshki Mahdi ,   Department of Health Education and Health Promotion, School of Health, Gonabad University of Medical Sciences, Gonabad, Iran., Basiri Moghadam Mahdi ,   Department of Pediatric Nursing, Social Development and Health Promotion Research Center, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran., Delshad Ali ,   Department of Community Health Nursing & Nursing Management, Social Development and Health Promotion Research Center, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran.
Published: February 2022

Background: The aim of this study was to determine the effect of continuous care model application on body mass index (BMI) and lifestyle of middle-aged obese. Methods: 105 obese middle-aged were selected and assigned randomly to two groups. The data were collected using a meter, scale, and Walker health promotion lifestyle questionnaire (HPLP II). participants completed the questionnaire before undergoing the intervention, one, two, and three months after the intervention. Results: There was no significant difference between the experimental and control groups before the intervention considering all of the studied variables. However, a significant difference was observed between groups after the intervention in terms of lifestyle dimensions and obesity control performance. Conclusion: Considering the results of current study, the continuous care model can be effective for improving the lifestyle and health of middle-aged obese. Therefore, this model is recommended as a framework to design an overweight and obesity prevention plan.
Effectiveness of the Hidden Curriculum on Affective Attitudes of High School Students Toward Learning
Authors:   Department of Educational Sciences, Faculty of Humanities, University of Hormozgan, Bandar Abbas, Iran., Raissi Ahvan Yaghoob
Published: February 2022

Background: The effectiveness of the hidden curriculum is stronger than the explicit curriculum from the perspectives of curriculum experts and medical education specialists. These effects are especially strong in transmitting values, norms, and medical professionalism. So, the importance of the hidden curriculum and its impact on educating medical students is undeniable. The present study aimed to explore the effect of the hidden curriculum components on affective attitudes of students toward learning, and to create a better learning and educational setting. Methods: The research was a mixed-method using a cross-sectional survey in the quantitative section. A case study (phenomenological analysis of lived experience type) and the interviews were used in the qualitative part. The study population consisted of 277 male high school students in District 1 of Bandar Abbas Port, Iran, in the 2019-2020 academic year. They were selected through the cluster sampling method and randomly assigned to the experimental research. Results: The results of multiple regression analysis showed a correlation (0.627) between the components of the hidden curriculum with affective attitudes of learning (P<0.95). The quantitative findings showed the mean scores of most components in exceptional talents (SAMPAD) high school students were significantly higher than the mean scores in public and non-public high schools students (P<0.05). Moreover, the results of the path analysis showed that the hidden curriculum has a positive and significant relationship with the three components of affective attitudes of students toward learning.. Conclusion: Generally, the hidden curriculum plays a vital role through the implicit transfer of values, attitudes, and skills to students, especially on affective attitudes, so that these issues should receive more attention by the educators in every educational setting.
Beliefs About Medicines and its Relationship With Medication Adherence in Patients With Chronic Diseases
Authors:   Department of Nursing, Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran., Baghcheghi Nayereh , Koohestani Hamid Reza ,   Department of Nursing, Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran.
Published: February 2022

Background and Objectives: Patients’ beliefs about medicines can affect their adherence to the medicines. The aim of this study was to determine beliefs about medicines and medication adherence and its associated factors in patients with chronic diseases. Methods: In this cross-sectional descriptive study, 268 patients with chronic diseases in 2019-2020 were included by convenience sampling method. The beliefs about medicines questionnaire and the Medication Adherence Scale were used for data collection. Data were analyzed in SPSS version 20 using One-Way Analysis of Variance (ANOVA), independent t-test and Pearson correlation coefficient at the significance level of α = 0.05. Results: The Mean±SD score of beliefs about medicines in terms of harms of medicines was 2.53±0.71, in benefits of medicines was 4.27±0.49 and overdose of the medicines was 3.23±0.79.There was a relationship between all three dimensions of beliefs about medicines with medication adherence (P<0.05). There was a direct relationship between the use of herbal medicine and belief in the harms of medicines (P<0.05). In addition, there was a relationship between gender and education level with belief in the benefits of the medicines (P<0.05). Conclusion: Some chronic patients’ beliefs about the drug were not appropriate and they believed that the drugs were harmful and that the drugs were over-prescribed by doctors. Belief in the harms of the medicines, the benefits of the medicines, and the overdose of the medicines are associated with medication adherence in patients with chronic diseases. Patients should be encouraged to express their views on medications in order to improve patients’ beliefs about medication.
Escala para Avaliação de Náuseas e Vômitos Relacionados à Quimioterapia: Tradução e Adaptação Transcultural
Authors: Isidoro Geovanna Maria , Ferreira Ana Cristina Gonçalves , Paiva Eliza Mara das Chagas , Amaral Jodi Dee Hunt Ferreira do , Meireles Everson Cristiano de Abreu , Garcia Ana Cláudia Mesquita
Published: February 2022

Introdução: Náuseas e vômitos induzidos por quimioterapia acometem cerca de 70-80% dos pacientes com câncer. Assim, é importante a utilização de um instrumento para avaliar melhor esses sintomas, visando a um tratamento mais adequado. Objetivo: Traduzir e adaptar culturalmente a escala Morrow Assessment of Nausea and Emesis para o contexto brasileiro. Método: Estudo correlacional do tipo survey, com tradução e adaptação cultural da escala segundo o protocolo da European Organization for Research and Treatment of Cancer – Quality of Life Group (EORTC-QLG). A amostra foi constituída por 160 pacientes em tratamento quimioterápico em uma clínica de oncologia. No processo de validação, realizaram-se análises de correlação multimétodos entre os itens da escala Morrow Assessment of Nausea and Emesis e os escores das escalas visuais numéricas de náusea e vômito com nível de p<0,05. Resultados: O autor da escala autorizou a tradução. A escala Morrow Assessment of Nausea and Emesis e as escalas numéricas apresentaram correlações significativas (p<0,01; p<0,05), sendo que os itens que apresentaram correlação mais forte das escalas numéricas foram os que se referiram à avaliação de náusea e vômito pós-quimioterapia. Já os itens destinados à avaliação desses sintomas no momento pré-quimioterapia e ao uso da medicação antiemética e sua eficácia apresentaram associações fracas com as escalas numéricas. Conclusão: A escala Morrow Assessment of Nausea and Emesis apresentou-se adequada para a avaliação de náuseas e vômitos induzidos por quimioterapia no contexto brasileiro.
Gobernanza social e inteligente para el Gobierno Autónomo Descentralizado Municipal del cantón Tulcán
Authors: Quenguán Mavisoy Kevin Javier
Published: February 2022

La presente investigación, se propuso estudiar la estructura organizativa del Gobierno Autónomo Descentralizado Municipal del Tulcán para la construcción de una gobernanza social e inteligente. En este sentido, dado los cambios sociales y tecnológicos acelerados es imprescindible que la institución municipal adopte nuevos modelos de gestión, para aumentar los niveles de eficiencia y eficacia para mejorar la calidad de vida de los ciudadanos de una forma moderna. En tal virtud, se fundamentó de una manera conceptual y teórica la organización estructural del gobierno local tulcaneño. Por otro lado, se señaló que las dimensiones del modelo de gobernanza social e inteligente son aplicables al funcionamiento administrativo de la institución municipal. Esto se realizó, por medio de una metodología cualitativa con un enfoque fenomenológico e interpretativo, el cual se sustenta en conocer la posición subjetiva de los funcionarios municipales. Por otra parte, el objetivo de este trabajo fue analizar la organización estructural del GAD Municipal de Tulcán para la construcción de una gobernanza social e inteligente. Al mismo tiempo, la interrogante de la investigación fue ¿Qué elementos conceptuales permiten conocer la estructura funcional de los gobiernos municipales? Finalmente, se puede establecer que a nivel organizativo el gobierno local de Tulcán sí permite adoptar elementos del modelo de gobernanza social e inteligente. Así, por ejemplo, la aplicación del valor público y el uso de tecnología para mejorar la prestación de servicios públicos.
Sexualidad socioafectiva de los jóvenes con discapacidad intelectual
Authors: Criollo Castro Carlos Hernando , Enríquez Gómez Ana Karina
Published: February 2022

El objetivo de esta investigación fue identificar la sexualidad socioafectiva de un grupo de jóvenes con discapacidad intelectual. La metodología aplicada consistió en la cualitativa mediante investigación-acción; los instrumentos utilizados fueron la observación, entrevistas semiestructuradas, diario de campo y grupos de enfoque conformados por 20 sujetos. En cuanto a los resultados, se determinó que los jóvenes con discapacidad presentan barreras para acceder a una información clara y pertinente sobre la sexualidad, especialmente orientada por los padres, dejándolas en situación vulnerable frente a enfermedades, lesiones y abusos. Por ello, se concluye que la falta de información y de formación de los padres, acudientes y de los jóvenes con discapacidad intelectual hacen que exista aún la exclusión o aislamiento social.
Antagonistic effect of Bacillus subtilis isolated and identified from different honey species against Klebsiella pneumoniae bee pathogens
Authors: Lakhman A. R. , Galatiuk O. Ye. , Romanishina T. A. , Behas V. L.
Published: February 2022

The search for alternative methods for treating and preventing bee dysbacteriosis is a priority for beekeeping as a branch of veterinary medicine. Lime honey, buckwheat honey, flower honey, forest honey, and acacia honey were tested to evaluate their antagonistic effect against a test culture of enterobacteria of bees of Klebsiella pneumoniae species. The study was conducted in several stages: 1. Determine the activity of honey microflora against a pure culture of enterobacteria of bees of Klebsiella pneumoniae bee pathogens; 2. The identification and isolation of Bacillus subtilis – bacteria-antagonists against Klebsiella pneumoniae bee pathogens; 3. Determine the antagonistic effect of pure culture of Bacillus subtilis against a pure culture of enterobacteria of Klebsiella pneumoniae bee pathogens. The antagonistic action of honey microorganisms and the determination of the most effective honey species were established by the diffusion method in agar wells. Staining of typical colonies from different types of honey revealed bacillary colonies of Gram-positive bacilli with endospores. Isolation of clean culture was conducted by a method of Gold. The cultural, tinctorial, and morphological signs of bacteria have been consistently determined in all investigated kinds of honey and coincided with characteristics of the Bacellaceae family. Specific belonging of bacteria-competitors was identified by biochemical typing. After determining their physiological properties in reactions and tests (activity of catalase, oxidase, urease, the ability to grow at different temperatures and to ferment carbohydrate substrate), the distinguished stamms of microorganisms from the investigated kinds of honey belong to the type of Bacillus subtilis. The repeated estimation of antagonistic action of pure cultures of Bacillus subtilis (isolated from each type of honey) against a pure culture of enterobacteria of bees of Klebsiella pneumoniae species confirmed their high activity. This type of microorganisms can represent the alternative component in probiotics at the therapy of dysbiosis of bees.
MAKNA AREK”CELURIT”BAGI GENERASI Y DI KABUPATEN PAMEKASAN
Authors: Anggraini Dian Mego , Riski Safitri Aizun , Muhyatun Muhyatun
Published: February 2022

Bagi masyarakat Madura, Arek”Clurit”tidak dapat dipisahkan dari budaya dan tradisi disana sampai saat ini. Terutama bagi generasi Y disana yaitu Kelompok anak muda yang juga disebut generasi milenium adalah mereka yang berusia belasan tahun hingga awal tiga puluhan (lahir awal 1980 hingga awal 2000) sendiri sudah mengenal betul makna senjata tradisional arek”clurit”.

Metode yang digunakan menggunakan pendekatan Kualitatif dengan pengambilan data secara wawancara. Penelitian Etnografi ini bertujuan untuk mengetahui apakah ada perubahan dalam memaknai arek ”clurit” bagi genearasi Y yang berasal dari Kabupaten Pamekasan.

Dari hasil penelitian dapat dilihat makna arek’clurit’ bagi generasi Y di Kabupaten Pamekasan. Makna arek”clurit” itu sendiri fungsi secara fisik sebagai senjata tajam, senjata tradisional masyarakat Madura, media pembelajaran pada perguruan pencak silat, sebagai alat pertanian. Secara fungsi sosial arek”clurit”sebagai senjata tajam untuk mempertahankan harga diri dan bentuk keberanian, seperti halnya yang digunakan jika carok atau hanya untuk pegangan jika dalam situasi bahaya istilah lainnya “nyikep”

Penelitian ini diharapkan agar generasi Y di Kabupaten Pamekasan dalam memaknai arek”clurit”dapat lebih dikembangkan sehingga dapat melestarikan senjata tajam khas dari Madura tersebut baik secara fungsi fisik maupun secara fungsi sosialnya
Road pricing schemes: policy lessons from the Bay Bridge in San Francisco
Authors: Brioux Paul
Published: February 2022

As cities develop and urbanize, and space becomes increasingly valuable, additional pressures are placed on all systems including transportation. Road pricing has been used to generate revenue, mitigate congestion, and reduce pollution. However, implementing road pricing schemes has been difficult, given its contentious nature. This study begins by providing a brief literature review of road pricing and highlighting lessons from key road pricing schemes that have emerged throughout the last twenty years. While previous studies have been explored extensively for their successes and limitations, the Bay Bridge has been comparatively understudied. The Bay Bridge showcases atypical characteristics that have influenced construction and pricing structures throughout its history. Given multiple case studies, and a more in-depth knowledge of the Bay Bridge, the current study identifies lessons that can be applied for the Bay Bridge as it continues to evolve and for the broader future of road pricing internationally.

Key words: Road Pricing, Congestion Charging, Pollution Mitigation, Public Opinion, Variable Pricing
Smokestack perceptions: exploring opportunities for intensification and light-industrial mixed use on Geary Avenue
Authors: Smiciklas Alexander
Published: February 2022

The high value of land, strain from rising property taxes, and pressure to redevelop impacts low-rise industrial users in Toronto and is leading to a dwindling supply of industrial employment land. The push for ‘highest and best use’ often leads to mixed-use development, common in most urban areas. Currently, most mixed-use projects deliver Commercial Residential (CR), meaning industrial users, which provide

competitive wages and have linkages to other industries that benefit the overall economy, have been largely left out of the conversation. This research explores how light industrial uses could be integrated into new mixed-use development to meet the demands of intensification, while adopting measures to incentivize its protection and vitality. Case study exploration from Vancouver and San Francisco, and in-depth subject area analysis prompt recommendations for a more diverse mix including compatible industrial use on Geary Avenue, one of Toronto’s remaining urban industrial corridors.

Key words: production, distribution, repair (PDR); light industrial; mixed-use; intensification
Molecular Docking Studies of Spirostans as MAPK14 (P38α) Inhibitors and Their Potential Use against Cancer
Authors: Lopez-Castillo Guiee Niza , Alatriste Victorino , Sandoval-Ramírez Jesus , Luna Felix , Carrasco-Carballo Alan
Published: February 2022

Spirostans (SPs) are chemical products widely distributed in the plant kingdom; currently, they are studied by their medical applications. Cancer has a high incidence in humans; it reaches second place worldwide deaths. In molecular biology, it has been accepted that Mitogen-Activated Protein p38alpha Kinase (MAPK14 (p38α) is implicated in the regulation of cancer. This study aimed to identify SPs as potential MAPK14 (p38α) inhibitors. From a set of 133 modified SPs, SwissTargetPrediction platform, and molecular docking, it was obtained that 129 chemical structures had molecular interaction with the MAPK14 (p38α). From those molecules, 123 were bound to a specific inhibition site of MAPK14 (p38α), and 6 of the structures resulted in inhibitors similarly to minocycline and dasatinib. One SP had binding couple energy (BCE, kcal/mol) as that of fostamatinib. In addition, 115 modified SPs had better BCE than the minocycline but not as that using fostamatinib. The key amino acids (aa) for the protein kinase MAPK14 (p38α) inhibition were Arg 70, Asp 168, Lys 53, His 148, and Ile 145, at a different interaction level. The BCE was enhanced when the H atom was substituted in C-2, C-11, and C-17 SPs positions. Similarly, the αOH group at C-5 and C-6 upgraded BCE. Stereochemistry and substitution at C-3, C-12, and C-25 did not present significant differences (Kruskal-Wallis test, p <0.05). From all this ensemble of results, it is foreseeable that the SPs can be an option for MAPK14 (p38α) inhibition, a key modulator in cancer processes.
New Approach to create an Effective Natural Treatments of Infections caused by Human Papillomavirus
Authors: Dunjic Momir , Turini Stefano Giuseppe , Stanisic Slavisa , Sulovic Nenad , Cvetkovic Sasa , Mihajlovic Dejan , Dunjic Marija , Simic Dusan , Dunjic Katarina
Published: February 2022

Human Papillomavirus (HPV) has a double-stranded DNA (dsDNA) genome. Infections, mainly sexually transmitted, usually resolve spontaneously. However, if the infection persists over time, lesions of the skin and mucous membranes tend to appear, notably mucosal lesions in the cervix or the appearance of warts. Some of those slowly progress to cancers such as cervical, oral, anus, esophagus, and larynx carcinoma. Diagnosis of an HPV infection is made by Papanicolaou test (Pap test) or molecular screening such as the HPV DNA Test. Treatment with natural products is based on essential oils. The main point of this work is to identify natural molecules from vegetal derivation capable of inhibiting the proliferation of HPV-16 with the same and/or superior affinity as regular drugs used in pharmacological treatment. Once we have identified the main components in these plants, we have applied molecular docking software 1-Click Docking, for virtual testing of those, on main antigenic determinants of HPV-16 as oncoproteins E6 and E7 as well as major capsid protein L1. The major active component to bind oncoprotein E6, apigenin, has shown an affinity bigger than other molecules. For major capsid protein L1, apigenin has shown one level of affinity similar to conventional drugs. These results have shown how it is possible, with natural products present in our daily lives, to inhibit the proliferation of HPV.
HUBUNGAN ANTARA WAKTU TUNGGU PELAYANAN RESEP RACIKAN TERHADAP KEPUASAN PASIEN DI APOTEK MEDIRA FARMA KOTA BENGKULU BULAN APRIL TAHUN 2021
Authors: Yustisia Nova , Versita Riana , Yolanda Sefty , Dominica Dwi
Published: February 2022

Pharmaceutical is a direct and responsible service to patients related to pharmaceutical preparations with the aim of achieving good results that are sure to improve the quality of life of patients. One of the quality of pharmacy services is waiting time. The purpose of this study was to see the relationship between waiting time for concoction prescription services and patient satisfaction at the Medira Farma Pharmacy, Bengkulu City in April 2021. This study used observational analytic method with astudy approach cross sectional. The research instrument is an observation sheet, the sample of this research is 30 respondents. The sample was determined using  purposive sampling technique. Data analysis was carried out using the chi square statistical test.. The results of the study showed that the level of patient satisfaction at the Medira Farma Pharmacy was 86.67% satisfied and 13.33% dissatisfied, while the waiting time for concoction prescription services at Medira Farma Pharmacy was said to be in accordance with the standard of 73.33% and not according to the standard of 26 ,67%. In thestatistical test chi square , the p value = 0.257 with the value = 0.05. The results of the data can be concluded that there is no relationship between waiting time for concoction prescription services to patient satisfaction at the Medira Farma Pharmacy, Bengkulu City with a closeness level of 0.23 which means low. The advice given is that Medira Farma Pharmacy should provide comfortable and adequate waiting room facilities to avoid patients feeling bored.
PENGGUNAAN BERBAGAI MACAM VAKSIN PADA TERAPI KONDILOMA AKUMINATA ANOGENITAL
Authors: Wirman Jefrizal , Anum Qaira
Published: February 2022

Kondiloma akuiminata anongenital (KAA) merupakan infeksi Human papillomavirus (HPV) yang terjadi pada anogenital yang biasanya bermanifestasi sebagai papula atau plak lunak pada genitalia eksterna, kulit perianal, perineum, atau inguinal. Di Indonesia, 13 rumah sakit (RS) pusat pendidikan spesialis kulit kelamin, terdapat peningkatan kasus kondiloma akuminata dalam 5 tahun terakhir (2007-2011). Di Poliklinik Divisi Infeksi Menular Seksual (IMS) Kulit dan Kelamin RSUP Dr M DJamil Padang, tahun 2019 tercatat 36 kasus baru dan total kunjungan pasien kondiloma akuminata yang kontrol selama tahun 2019 sebanyak 288 kunjungan. Terapi KAA yang berkembang saat ini masih menunjukkan angka rekurensi yang cukup tinggi. Immunoterapi menggunakan vaksin mulai dikembangkan sebagai alternatif terapi bagi KAA. Vaksin HPV, Mumps Measles Rubella (MMR), Bacillus Calmette-Guerin (BCG), dan Mycobacterium indicus pranii (MIP) memberi manfaat terapetik pada KAA. Penggunaan vaksin HPV dapat dilakukan secara intralesi maupun intramuskular. Vaksin MMR dan BCG diinjeksikan secara intralesi. Sementara, vaksin MIP diberikan secara intradermal pada kedua deltoid. Keseluruhan vaksin diberikan dalam beberapa dosis dengan selang waktu yang berbeda. Stimulasi kekebalan tubuh seluler diperkirakan menjadi dasar kebermanfaatan vaksin sebagai terapi pada KAA. Belum ada studi yang mengungkapkan efek samping pemberian vaksin sebagai immunoterapi pada KAA yang bermakna.
EFEKTIFITAS KOMPRES HANGAT DAN AKUPRESUR TERHADAP NYERI PUNGGUNG BAGIAN BAWAH PADA IBU HAMIL TRIMESTER III LITERATURE REVIEW
Authors: Prabandani Kirana Dwi , Leny Wulandari Rr. Catur , Zahriah Atika
Published: February 2022

Selama masa kehamilan banyak perubahan fisik maupun psikologis yang terjadi pada wanita, salah satunya adalah membesarnya uterus yang dapat menimbulkan nyeri punggung. Nyeri punggung merupakan suatu ketidaknyamanan pada ibu hamil terutama pada trimester III. Nyeri punggung yang tidak tertangani dapat mengganggu aktivitas sehari-hari. Ibu hamil dapat mengurangi nyeri punggung dengan menggunakan terapi non-farmakologis diantaranya kompres hangat dan akupresur. Tujuan literatur review untuk mengetahui efektifitas kompres hangat dan akupresur terhadap nyeri punggung bagian bawah pada ibu hamil trimester III. Metode yang digunakan adalah literature riview pada database jurnal kesehatan yaitu Google Scholar diperoleh 59 artikel, 27 artikel di Pubmed, 5 artikel di The Lancet, 28 artikel di Springer dan di Elsevier 1 artikel terbitan 10 (sepuluh) tahun terakhir. Hasil studi literatur melalui database menunjukkan bahwa kompres hangat dan akupresur merupakan metode yang efektif untuk mengurangi keluhan nyeri punggung pada ibu hamil trimester III. Kompres hangat dan akupresur sama-sama memiliki efektifitas terhadap penurunan skala nyeri punggung, tetapi kompres hangat lebih mudah digunakan  dibandingkan akupresur yang harus dilakukan dan didampingi oleh seseorang yang terlatih.
ANALISIS PROTEIN PADA MEDIUM TERKONDISI SEL PUNCA MESENKIMAL
Authors: Pradifta Reysa , Marlina Marlina , Lucida Henny
Published: February 2022

Sel punca mesenkimal / mesenchymal stem cells (MSC) merupakan sel yang paling banyak membentuk organ stroma sumsum tulang belakang. MSC memiliki kemampuan memperbarui diri sampai jumlah yang cukup untuk menyembuhkan luka. Media tempat tumbuh MSC yang belum berdiferensiasi disebut media terkondisi sel punca mesenkimal atau mesenchymal stem cells-conditioned medium (MSC-CM) dan mempunyai efek seperti MSC. Pada penelitian ini dilakukan analisa kandungan protein yang terdapat dalam MSC-CM yang diisolasi dari jaringan adiposa. Analisis protein menggunakan uji Ninhidrin dan Sodium Dodecyl Sulphate  Polyacrylamide Gel Electrophoresis (SDS-PAGE). Hasil Uji Ninhidrin menunjukkan terjadinya perubahan warna dari merah muda ke ungu yang berarti hasil positif terdapat asam amino. Hasil uji dengan metoda SDS-PAGE (Sodium Dodecyl Sulphate  Polyacrylamide Gel Electrophoresis), profil protein MSC-CM diamati berdasarkan berat molekulnya. Protein terdeteksi pada ukuran 38 kDa – 98 kDa yang terdiri dari VEGF pada 45 kDa, EGF containing fibulinlike pada 55 kDa, ECM protein 1 pada 61 kDa dan TGF? pada 75 kDa. Berdasarkan uji identifikasi protein pada MSC-CM didapatkan hasil yang menunjukan positif adanya kandungan protein yang diprediksi sebagai faktor pertumbuhan yang disekresikan oleh MSC.
PENGARUH TERAPI BERMAIN CLAY TERHADAP KECEMASAN PADA ANAK USIA PRA SEKOLAH (3-6 TAHUN) YANG MENJALANI HOSPITALISASI DI RUMAH SAKIT BENGKULU
Authors: Fusfitasari Yenni , Eliyanti Yeni
Published: February 2022

Permasalahan : Kecemasan merupakan perasaan yang paling umum dialami oleh pasien anak yang sedang mengalami hospitalisasi. Tujuan Penelitian : Mengetahui pengaruh terapi bermain clay terhadap kecemasan pada anak usia pra sekolah (3-6 tahun) yang menjalani hospitalisasi di Rumah Sakit Bengkulu. Metode Penelitian : Jenis penelitian yang digunakan adalah pre eksperimental design  Hasil : Hasil penelitian didapatkan nilai rata-rata kecemasan pada anak usia pra sekolah (3-6 tahun) yang menjalani hospitalisasi sebelum terapi bermain clay dengan nilai rata-rata kecemasan adalah 11.75. Hasil penelitian didapatkan nilai rata-rata kecemasan pada anak usia pra sekolah (3-6 tahun) yang menjalani hospitalisasi setelah terapi bermain clay dengan nilai rata-rata kecemasan adalah 8.60. Hasil uji statistik didapatkan nilai p = 0,000, berarti < 0,05 (?) sehingga dapat disimpulkan bahwa ada pengaruh terapi bermain clay terhadap kecemasan pada anak usia pra sekolah (3-6 tahun) yang menjalani hospitalisasi di Rumah Sakit Bengkulu. Kesimpulan: Hasil penelitian dapat disimpulkan terdapat penurunan nilai rata-rata kecemasan pada anak usia pra sekolah (3-6 tahun) yang menjalani hospitalisasi sebelum dan setelah terapi bermain clay dan dengan melihat nilai statistik didapatkan bahwa ada pengaruh terapi bermain clay terhadap kecemasan pada anak usia pra sekolah (3-6 tahun) yang menjalani hospitalisasi di Rumah Sakit Bengkulu.
ТЕОРЕТИЧНІ ОСНОВИ ДОСЛІДЖЕННЯ ПРОБЛЕМИ КОРЕКЦІЇ ЕМОЦІЙНОЇ СФЕРИ В МОЛОДШОМУ ШКІЛЬНОМУ ВІЦІ
Authors: Гуртовенко Н.
Published: February 2022

Дана стаття присвячена розвитку емоційної сфери дітей. Провідними методами у вивченні проблеми є спостереження, анкетування, психологічне тестування. У статті розглядається роль освітніх установ у розвитку емоційної сфери дітей, а також визначаються форми сприяння розвитку емоційного благополуччя дитини (вправи, ігри, тренінги).
ТЕОРИТИЧНІ ОСНОВИ ДОСЛІДЖЕННЯ ПРОБЛЕМИ ПРОФЕСІЙНОЇ АДАПТАЦІЇ МОЛОДШИХ ОФІЦЕРІВ ДО ВІЙСЬКОВО-ПРОФЕСІЙНОЇ ДІЯЛЬНОСТІ
Authors: Кіщук Л.
Published: February 2022

У статті розглянуто філософські, психофізіологічні, соціологічні підходи до розуміння змісту адаптації. Проаналізовано етапи психічної адаптації і дезадаптації. Відзначено важливу роль інтелекту в процесі адаптації. Представлено трактування проблеми професійної адаптації у військовій педагогіці. Досліджено структурні компоненти професійної адаптації молодших офіцерів та надано їм змістовну характеристику.
СУЧАСНІ ПІДХОДИ ДО ПСИХОТЕРАПІЇ НАРКОТИЧНОЇ ЗАЛЕЖНОСТІ
Authors: Мостова Т.
Published: February 2022

У статті здійснено критичний аналіз основних психологічних підходів до проблеми наркоманії: біхевіорального, психоаналітичного когнітивного, системного, гуманістичного, екзистенційного, теорії трансактного аналізу, онтосуб'єктного підходу. Їх змістовний аналіз дав можливість побачити багатоаспектність проблеми та припустити, що в рамках існуючих сьогодні напрямків у психології жодна з теорій чи концепцій повністю не пояснюють феномени, пов'язані з виникненням наркотичної залежності, що перешкоджає розробці методів їх діагностики, лікування та профілактики. На підставі онтосуб’єктного підходу (В.С. Березін, К.С. Лисецький) розроблено структурну психодіагностичну модель особистості з наркотичною залежністю.
La política de contención migratoria y su impacto en las condiciones del desplazamiento migrante de origen centroamericano por México
Authors: Burgueño Angulo Nayeli
Published: February 2022

El objetivo del presente trabajo es analizar sobre la situación crítica del desplaza-miento migrante centroamericano, caracterizado por la intensidad de la movilidad forzada de miles de personas provenientes principalmente del llamado Triángulo del Norte, en su búsqueda por llegar a los Estados Unidos. La presencia y magnitud del desplazamiento de personas ha modificado no sólo los patrones de la migra-ción en su tránsito por México, sino también las formas de organización migratoria a través de Caravanas que se hicieron presentes a partir de 2018, con el consecuen-te recrudecimiento de las políticas restrictivas por parte de los gobiernos de Méxi-co y Estados Unidos. Lo anterior ha conllevado a una reconfiguración en las dinámicas transfronterizas, acompañada de un discurso de seguridad nacional ba-sado en la discriminación y criminalización de la migración y la implementación de esquemas de contención de los flujos migratorios, traducidos en el reforzamien-to de las fronteras y una política restrictiva de solicitantes de asilo. Situación que vulnera las condiciones del desplazamiento de la población migrante, caracteriza-da por la exclusión, marginalidad y violencia, que se profundizan con la pandemia de la COVID-19.
Strategic Human Resource Management and Performance of Selected Deposit Money Banks in Abuja, Nigeria
Authors: Marcus Garvey ORJI  , Babatunde Kizito OLANIYI  , Thomas Oyetunde OLADELE  , Abe MHIRNA
Published: February 2022

The objective of this study was to assess the impact of strategic human resource management (extensive training, empowerment, performance appraisal and performance based pay) on organizational performance (service quality) of selected deposit money banks in Abuja. The study was a survey research sampling the opinion of 77 staff of Zenith, Polaris, First bank and First city monument bank, Bwari branch. Their opinion was collected using a structured questionnaire. The data obtained was analysed using descriptive and inferential statistics. The hypotheses were tested by means of correlation and multiple regressions. The study found significant relationship between extensive training, empowerment and performance based pay and service quality. There is also significant relationship between performance appraisal and service quality. The study concluded that Strategic Human Resource Management (SHRM) is important for improved service quality in Nigerian deposit money banks and therefore recommended among others the necessity for every staff of banks to be properly equipped with the skills, technical know-how required to carry out their task effectively; Training programs should target specific need areas of the employees and this should be organized timely given the rate of market and technology changes; Performance appraisal should be centred on pointing out the strength of the employees whilst addressing ways to improve them in areas where they are weak. Also Banks’ human resource management should formulate and implement an active reward policy linked to the overall banks strategy. The reward policy should ensure that employees’ rewards are matched with the employees’ efforts.
Continuous professional development: An overview from English language teachers in east Kalimantan
Authors: Halim Abdul , Lin Yih-Sheue , Mustofa Mustofa , Khatimah Khusnul
Published: February 2022

The purpose of the study was to explore how continuous professional development is conducted, who conducts it, and the factors that influence it. According to the laws of the Republic of Indonesia, teaching is a professional job that requires certain educational and training qualifications so that teachers can become professional personnel. By seeing the importance of professionalism in this work and in order to see the picture of the CPD of teachers in East Kalimantan, this research is important to carry out. This research uses a qualitative case study method. The subjects of this study were teachers (n=10) from ten schools in Samarinda, Kutai Kartanegara, and Balikpapan. Data were collected using a CPD questionnaire and interviews. The data obtained were analysed and presented with descriptions and tables or charts. The data indicated that most of the teachers participated in the study are aware of the components of professional teacher indicated from the government laws. The study also reveals how the CPD is conducted by different stakeholders. Some suggestions are proposed based on the results of the study.
The implementation of TPS (think pair share) cooperative learning model aided by Google hangouts in literary expression course
Authors: Hiasa Fina , Supadi Supadi , Yanti Nafri
Published: February 2022

This study aims to determine how the application of the TPS (Think-Pair-Share) type of cooperative learning model assisted by Google Hangout can improve the quality of learning in seventh semester students of the Indonesian Language Education Study Program, FKIP UNIB, in the Literary Expression course. The data analysis technique used in this study was a descriptive method that produced an overview of the extent to which the quality of learning has improved by using the TPS (Think-Pair-Share) type of cooperative learning model assisted by Google Hangouts for students who were the research samples. This classroom action research was carried out in two cycles, and each cycle used the main digital learning room, namely the Google Hangout application. Data collection techniques were carried out through non-test techniques at the beginning and end of cycles I and II using questionnaires and observation sheets. In the first cycle, the results obtained had not reached the expected target. The target required was reached in the second cycle. The learning outcomes of the second cycle of students obtained an A score of 13 people (36%), a B value of 18 people (50%), a C value of 5 people (14%), and a D value of 0 people (0%). These results indicate that the target achievement of 30% had been successfully achieved by applying the TPS learning model assisted by the Google Hangouts.
Evaluasi Pelaksanaan Pembelajaran Daring Pada Masa Pandemi Covid-19 Di SD Islam Terpadu
Authors: Alexon Alexon , Wachidi Wachidi , Windayani Windayani
Published: February 2022

This research aimed to evaluate the implementation of online learning during the COVID-19 pandemic in terms of the context aspect, Input aspect,Process aspect, and Product aspect. Data collection techniques with online questionnaires through Google Forms and documentation. The samples of this research were 29 teachers, 69 students, and 68 parents from grades 4-6 SDIT Hidayatullah Bengkulu City. The evaluation used the CIPP model and analyzed descriptively quantitatively by calculating the mean. The conclusions of this research were: (1) in terms of context, online learning during the COVID-19 pandemic at SDIT Hidayatullah Bengkulu City was very well done, (2) in terms of input, online learning during the COVID-19 pandemic SDIT Hidayatullah Bengkulu City was well implemented, (3) in terms of Process aspect, online learning during the COVID-19 pandemic SDIT Hidayatullah Bengkulu City was carried out well, (4) in terms of the Product, online learning during the COVID-19 pandemic SDIT Hidayatullah Bengkulu City was quite well done.
Perinatal Outcome in Newborns of Women with Gestational Diabetes Mellitus
Authors: Baysal Bora , Oner Oznur
Published: February 2022

Objective: This study was planned to determine the perinatal outcomes of the newborns of term pregnant women who were diagnosed with GDM and decided to have cesarean delivery. Materials and Methods: Thirty-five pregnant patients diagnosed with GDM were included in the study. The control group consisted of 35 patients who did not have any pregnancy-related disease and were decided to deliver with elective cesarean section. All participants were screened with a 50-g GCT at 24-28 weeks of gestation. Pregnant women with meeting the following laboratory criteria were accepted as GDM. If the serum glucose level was greater than 140 mg/dL on the 50-g GCT, a 100-g OGTT was applied. Diagnosis of GDM was confirmed if 2 of the blood glucose test results were above the following levels: fasting serum glucose ≥ 92 mg/dL and/or 1-hour glycemia ≥ 180 mg/dL, and/or 2-hour glycemia ≥ 153 mg/dL. Perinatal outcome between GDM subjects and control group was compared. All participants in GDM and control groups underwent cesarean deivery. Primary outcome measures included gestational birthweight, gestational age at delivery, stillbirth and neonatal death, minor and major birth defects. Results: While neonatal hypoglycemia was detected in 4 cases in the GDM group, it was found in one case in the control group. No stilbirth was detected in either the GDM group or the control group. While neonatal death was detected in one case in the GDM group, no neonatal death was observed in the control group. While mild preeclampsia was detected in one case in the GDM group, it was not found in the control group. Birth weeks and birth weights of the cases in both groups were recorded similarly. While 8 babies of 2500 grams or less were born in GDM cases, all of the cases in the control group were over 2500 grams. While prematurity was detected in two babies in the GDM group, no prematurity was reported in the control group. Neonatal intensive care needs were seen in three babies in the GDM group, and there were no infants in need of intensive care in the control group. Conclusions: There is a slight increase in low birth weight, prematurity and intensive care unit needs of babies born to mothers with GDM.
Gynatresia in Herlyn-Werner-Wunderlich Syndrome: A Case Report
Authors: Beserra Valentim Priscila Margarete Araujo , Martins Bernardes Jamile , Resende Volpini Flavia , de Alencar Aline Baffa , Silva Pelanda Dandhara Rocha da , Antônio Chambô Filho
Published: February 2022

Background: Female genital malformations are a consequence of abnormalities in the differentiation of the Müllerian ducts at different phases during embryogenesis, resulting in a variety of clinical outcomes. HerlynWerner-Wunderlich (HWW) syndrome is a rare congenital anomaly of the female urogenital tract involving the paramesonephric ducts (Müllerian ducts). The syndrome is characterized by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. Case: This paper describes the case of a 14-year-old girl presenting with pelvic pain, abdominal swelling and the triad that is characteristic of HWW syndrome. Diagnosis was based on the patient’s clinical history and imaging findings. The patient underwent surgery involving complete drainage of a hematocolpos retained in the obstructed vaginal cavity and resection of the vaginal septum. The procedure was successful in providing symptomatic relief. Twelve months following surgery, the patient’s menstrual cycles were regular, with no dysmenorrhea. Discussion: Greater understanding of this syndrome is crucial in ensuring that diagnosis is reached at an early stage, thus preventing complications such as retrograde menstruation, endometriosis, infections, adhesions, infertility, and acute or chronic pelvic pain.
Sexual Health after Menopause: A Qualitative Study
Authors: Olowokere RM Adekemi E. , Adedeji RM Ademidun O. , Olajubu RM Aanuoluwapo O. , Aladegboye RM Mercy K. , Irinoye RM Omolola O
Published: February 2022

Background: Menopause has been associated with decline in sexual well-being among women. The quality of sexual interactions in heterosexual relationship are increasingly being considered as an important indicator of positive health and quality of life. Objectives: This article describes the sexual health status of menopausal women and the challenges preventing them from having a fulfilling sexual life. Method: This was an exploratory qualitative interview. Seventeen (17) menopausal women were interviewed individually and face-to-face using semi-structured interview guide. The interviews were analyzed using content and thematic analysis. Results: The analysis yielded two themes for sexual health status; (a) good sexual health status and (b) poor sexual health status. Majority of the study participants claimed to have poor sexual health status. The challenges to having a fulfilling sexual life yielded four themes; (a) fear (b) lack of sexual partner (c) ageing process and (c) being breadwinner of the family. Conclusion: The study concludes that majority of the women in the study have poor sexual health status and diverse challenges to having a fulfilling sexual life. This article offers a premise for healthcare providers to see the necessity to inquire about sexual health from post-reproductive age women and to provide necessary support that can help improve their sexual health.
The Demographic Characteristics of Patients with Benign Ovarian Cyst and Histological Pattern in a Tertiary Center in Riyadh, Saudi Arabia
Authors: Farid Gehan , Chamsi Ahmed Talal , Swaraldahab Mohamed , Swaraldahab Hassan
Published: February 2022

Background: Benign ovarian tumours are a very common clinically encountered condition and rarely become malignant. The outcome is generally good, varying from asymptomatic big cysts to symptomatic ones with different sizes. Objective: To know the demography of patients, the types of cyst, presentation and management options. Thereafter, comparison of data with other national and international studies was done. Results: This retrospective cohort study was carried out in Security Forces Hospital, Riyadh in Saudi Arabia between January 1st, 2015 to January 31st, 2018. There were 67 cases of histologically diagnosed benign ovarian neoplasms in that period. The age range of 20-49 made up 72.1% of cases and a mean of 37 years, with a BMI of 20-36.9 Kg/m². 67.2% of cases were electively admitted and 88% of cases had ovarian cyst more than 5cm in size. The affected side was almost similar being 35.8% on right side and 32.8% on the left, 28.3% were bilateral and 2.99% were paraovarian cysts. 31.3% of patients were single and 10.4% multiparous. A parity of up to 6 constituted 41.8% of cases, 58.2% were managed by laparotomy and 41.8% had laparoscopic approach. 56.7% of cases were of epithelial origin, 17.9% functional cyst and 16.4% were Germ cell tumours. Sex cord variety were seen in 5.96% of cases and a combination of epithelial and stromal components made up 2.98% of cases. During the 2-D ultrasound studies done for all patients, 10.4% did not have concomitant Doppler studies done. Of those that had doppler, 8.9% were abnormal. Blood group O positive was seen in 52.2% of cases and 23.9% were ‘A’ rhesus positive and 11.94% were ‘B’ rhesus positive. 4.48% of cases were pregnant at the time of diagnosis. 13.4% had recurrence of cyst, abdominal pain was the main presentation in 59.7% of cases, palpable mass in 4.48%, 22.4% had previous Cesarean Section. Conclusion: To determine the incidence of histologically diagnosed types of benign ovarian neoplasm in a Tertiary hospital in Central part of Saudi Arabia and compare it with other regional areas, in same country, neighboring countries and international figures.Suggestions on certain aspects that were made includes improvements, and that could possibly be a future recommendation, on diagnosis and prognosis of ovarian neoplasm, such as different combinations of tumour markers (CA125 + HE4), surgical management, recurrence rate and blood groups.
Mosaic 47,XYY/45,X Presenting With Male Infertility: A Rare Case Report
Authors: Mohamad Zamri Wan Norizzati Wan , Mat Zin Nik Mohd Zulfikri , Mohd Nawi Nurul Alia , Anuar Aziati Aswari , Yunus Nazihah Mohd , Sulong Sarina , Alwi Zilfalil , Ankathil Ravindran
Published: February 2022

Sex chromosome aneuploidies are the most common chromosome abnormalities associated with infertility in adult men. 47, XYY syndrome also known as Jacob Syndrome (JS) is one sex chromosome aneuploidy. Majority of 47, XYY men show normal spermatogenesis while minority may have varying degrees of impairment in spermatogenesis. This case report discusses about a 32 year old Malay gentleman who was diagnosed to have azoospermia for which cytogenetic analysis revealed an abnormal mosaic 47,XYY/45,X karyotype pattern as the underlying genetic cause. Abnormal mosaic 47,XYY/45,X karyotype associated with infertility is extremely rare in human population and hence reported for its rarity.
Uji Fungsional Sistem PengukurSuhu Tubuh Berbasis Arduino Dengan Metode Blackbox Testing
Authors: Dean Haris Achmad Azrul , Sudaryanto Aris , Sulistyawati Dwi Harini
Published: February 2022

Selama terjadi wabah Covid-19, thermometer menjadi barang yang sangat dibutuhkan masyarakat. Hal ini karena salah satu kondisi yang umum dialami oleh penderita Covid-19 adalah demam. Namun thermometer biasa juga kurang efektif digunakan, terutama jika untuk penggunaan dengan intensitas tinggi, seperti di tempat tempat layanan umum. Selain karena membutuhkan waktu lama dalam pemeriksaan suhu, thermometer biasa penggunaanya juga harus bersentuhan dengan kulit badan, padahal hal tersebut rawan menularkan virus. Maka solusi yang mungkin adalah sebuah sistem pengukur suhu tubuh tanpa kontak. Penelitian ini melakukan pengujian keandalan sistem pengukur suhu tubuh tanpa kontak menggunakan metode blackbox testing. Berdasarkan hasil pengujian yang telah dilakukan, fungsional sistem telah 100% bekerja dengan baik.