bluuebunny/crossref_metadata_2025 huggingface dataset:
Learning and leading through COVID-19: Surprising findings from a year of disrupted field experience
Authors: Kapoyannis Theodora , Kendrick Astrid , Danyluk Patricia
Published: September 2024

When the COVID-19 pandemic necessitated the closure of Kindergarten-Grade 12 schools in Alberta, the authors, who are the Directors of Field Experience, at this local university saw this disruption as both a challenge and an opportunity (Danyluk, 2022). Over 400 preservice teachers were scheduled to begin their in-school practicum two days after the announcement of school closures. While most Bachelor of Education programs in Canada halted or postponed their field experience programs, the authors decided to move forward with an online practicum course. This chapter describes how we used collaborative professionalism (Hargreaves & O’Connor, 2018) to restructure field experience in response to the pandemic and the impact it had on student and field instructor learning. A community of practice was initiated by the Directors of Field Experience to support the instructors in the implementation of the online course and to come together as a community of learners in support of one another during this complex time. Survey and anecdotal data will be shared to illuminate the positive influence the pivot to the online field course had on students and instructors as well as the challenges we encountered as we navigated these uncharted waters as educational leaders.
A Review of Applications, Forms, Extraction, and Dissolution of Chitin
Authors: Hassen Tamara F. , AL-Jamal Lina Abd Oun , Kareem Ghufran
Published: September 2024

Background:
Polymeric organic particles made by organisms or natural biopolymers, are considered as greener materials, more environmentally friendly and durable. Because of its exceptional structural properties, wide abundant, lack of toxicity, biocompatibility, simplicity of alteration and promised potentials, chitin is a sustainable material. It is composed of β(1,4)-linked N-acetyl-glucosamine units and represents the most abundant structural polysaccharide of invertebrates, including such marine phyla as sponges, corals, annelid worms, mollusks, and arthropods. This biopolymer is mostly found in the skeletal structures of invertebrates, and plays a crucial role in their rigidity, stiffness, and other mechanical properties. Chitin is recognized as one of the universal templates in biomineralization, with respect to both biocalcification and biosilicification.
Conclusion:
This review is concerned with chitin. For a set of uses, chitin with its derivatives are receiving more and more attention. The popularity of this plentiful biopolymer has skyrocketed in recent years. Studies on the use of chitin show that these biopolymers have a lot of potential for managing wounds, getting rid of toxic metals, farming, bone regenerative engineering, etc.
Evaluation the Hematological Alterations in Females with Breast Cancer
Authors: Al-Maaroof Zainab W. , Al-khafaji Teeb M. Jaafar
Published: September 2024

Background: Cross-sectional research conducted in Baghdad province, women with breast cancer, both young and elderly, were evaluated alongside healthy persons to determine certain hematological parameters. This study aimed for evaluation the Hematological alterations in females with breast cancer.   
Materials and Methods: The investigation was conducted in private hospitals, forty women diagnosed with breast cancer and ten healthy controls were randomly sampled between 2020 and 2022. From each female patient and control , three milliliters of venous blood were given, which was then dispensed into an EDTA container, in order to evaluate the hematological parameters. Additional analyses utilizing the (Auto Hematology Analyzer) were carried out on the EDTA samples, including PCV, WBC, RBC, platelet count, and lymphocyte count. Procedures followed in the handbook for the testing. Using the conventional Westergren technique, the ESR was calculated.  
Results: The current results showed that there was a significant difference between the examined population and the control group in terms of mean RBC, PCV, platelets count, WBC, and lymphocytes, with a p-value of less than 0.05. In contrast, the control participants had considerably lower mean ESR levels (p < 0.05) compared to the breast cancer patients.
Conclusion:  breast cancer can affect all blood components including RBC, WBC, platelets and its related parameters.
Efektivitas Ifdil perceptual light technique untuk mengurangi social anxiety siswa obesitas
Authors: Arrahman Iqbal , Ifdil Ifdil , Karneli Yeni , Fadli Rima Pratiwi , Khairati Annisaislami
Published: September 2024

Obesitas pada remaja sering dikaitkan dengan permasalah psikologis, seperti stres, anxiety, depresi bahkan trauma dan PTSD. Obesitas dapat menjadi salah satu faktor yang beresiko bagi perkembangan social anxiety siswa. Social anxiety merupakan salah satu jenis gangguan kecemasan yang bersifat khusus. Pada gangguan ini penderitanya akan merasakan kekhawatiran yang berlebihan ketika berada di sekitar orang banyak. Beberapa gejala fisik yang dapat diamati adalah munculnya keringat dan gemetar saat berinteraksi dengan orang banyak. Sehingga siswa dengan gangguan ini cenderung untuk menghindari pertemuan dan kegiatan yang melibatkan orang lain. Oleh karena itu penting bagi siswa yang mengalami obesitas untuk mendapatkan bantuan psikologis yang sesuai. Salah satu bantuan yang dapat diberikan adalah dengan menggunakan teknik Ifdil Perceptual Light Technique (IPLT). Teknik IPLT merupakan sebuah alternatif pendekatan brief untuk mereduksi berbagai macam permasalahan psikologis, salah satunya kecemasan. Intervensi menggunakan IPLT dilakukan melalui modifikasi sensorik dan persepsi individu melalui spektrum cahaya. IPLT menggunakan kombinasi teknologi, bahasa pemrograman, dan beberapa pendekatan sebelumnya, yang bertujuan untuk mengurangi stes, kecemasan, trauma, fobia dan gangguan psikologis lainnya dalam waktu yang relatif singkat yaitu kurang dari sepuluh menit Penelitian ini bertujuan untuk menguji IPLT dalam mengurangi social anxiety siswa obesitas. Penelitian  ini  menggunakan  desain  subjek  tunggal  terhadap  satu subjek yang mengalami soial anxiety.Desain penelitian menggunakan desain A-B single subject penelitian. Instrumen yang digunakan  adalah  observasi, wawancara, teknik  scaling  dan menggunakan instrumen social anxiety. Hasil penelitian menunjukkan bahwa responden memiliki tingkat social anxiety tinggi sebelum intervensi. Namun setelah diberikan intervensi melalui IPLT tingkat social anxiety menurun. Hasilnya menunjukkan bahwa IPLT efektif untuk mengurangi social anxiety pada siswa obesitas.
Teacher-students interactions and Students’ attitude at international science faculty classes: in the context of biology and chemistry departments
Authors: Ratmanida Ratmanida , Ayudhia Honesty Yonanda , Adzanil Fuad Nabil , Putri Meutia Herza
Published: September 2024

In the context of globalization of education, where students often come from diverse cultural and academic backgrounds, interactions between teachers and students play a key role in effective learning experiences. This research emerged from awareness of the need to understand how interactions between teachers and students occur in international classrooms, particularly in biology and chemistry departments. This research aims to analyze differences in student interactions in international classes based on science faculties. This research is comparative research obtained through random sampling. The sample for this research was 88 students who were enrolled in the international class program at the science faculty. Data was collected using an in-class interaction instrument with 29 items. The analysis technique uses descriptive and independent sample t-tests. These findings indicate that there are significant differences in the level of interaction between students majoring in biology and chemistry in international classes. Apart from that, classroom interaction also provides opportunities for collaboration between students so that they can increase their self-confidence in their learning abilities. Building strong relationships among students also contributes to increasing positive attitudes towards learning through motivation and engagement.
Clinical assessment of the respiratory system in pregnant women on the background of nicotine addiction
Authors: Dzyubailo A. , Lotkov V.
Published: September 2024

Smoking is not only a modifiable risk factor for adverse pregnancy outcomes, it is primarily a risk factor for the development of pathology of the respiratory system, eventually turning into chronic obstructive pulmonary disease (COPD). The high prevalence of tobacco smoking among pregnant women, confirmed by numerous studies, demonstrates the underestimation of the high risks of COPD development. The present study substantiates the relevance of timely detection of pathological changes in the bronchi in smokers in primary care and the formation of motivations to quit smoking. It is the desired pregnancy that can cause complete cessation of smoking, thereby reducing the risks of developing not only the pathology of the smoker's lungs, but also the pathology of the fetus.
SISTEM INFORMASI COMPANY PROFILE UPA BIMBINGAN KONSELING DAN PEMBINAAN KARIR UNIVERSITAS MATARAM BERBASIS WEBSITE
Authors: Hanifah Fairuz , Ratnasari Dwi , Dwiyansaputra Ramaditia , Agitha Nadiyasari
Published: September 2024

UPA Bimbingan Konseling dan Pembinaan Karir Universitas Mataram merupakan unit penunjang akademik di bidang layanan bimbingan dan konseling serta pengembangan karir dan kewirausahaan. Pengelolaan informasi yang masih manual dan terpisah-pisah seringkali menimbulkan berbagai kendala, seperti kesulitan dalam mengakses informasi secara cepat dan tepat, kurangnya transparansi, serta kurang efisien dalam penyampaian layanan. Dengan Perkembangan teknologi informasi pada masa sekarang ini sangatlah luas dan juga telah merubah sebagian besar pekerjaan manusia yang dimana awalnya dikerjakan secara manual akan tetapi karena kemajuan teknologi informasi ini semua pekerjaan manusia dapat dikerjakan secara digital. Untuk memecahkan masalah yang ada, pada penelitian kali ini penulis menggunakan framework WordPress untuk membangun sebuah sistem informasi company profile untuk UPA Bimbingan Konseling dan Pembinaan Karir Universitas Mataram. Pengujiian sistem dilakukan dengan menggunakan metode System Usability Scale dengan melibatkan 27 responden. Hasil pengujian mendapatkan SUS Score sebanyak 77.5 yang berarti sistem informasi yang telah dibuat termasuk ke dalam kategori tingkat acceptability yaitu acceptable, grade scale kategori C, dan adjective rating kategori good.
OPTIMALISASI POTENSI MASYARAKAT DI PULAU LOMBOK MELALUI PELATIHAN BAHASA KOREA DAN BISNIS DIGITAL
Authors: Annuur Ali , Salsabila Raissa Calista , Devianur Dinda , Suhada Destia , Aulia Annisa Fitri , Maulidi M. Harish , Arimbawa I Wayan Agus
Published: September 2024

Program “2024 SNUSR Summer Corps in Indonesia” merupakan inisiatif kolaboratif antara Universitas Mataram, Universitas Nasional Jakarta, dan Seoul National University, yang bertujuan untuk memberdayakan masyarakat Lombok melalui pelatihan Bahasa Korea dan bisnis digital. Program ini dirancang untuk meningkatkan keterampilan bahasa Korea yang relevan dalam pariwisata dan bisnis, serta untuk memberikan pengetahuan praktis tentang bisnis digital kepada masyarakat. Pelatihan melibatkan pengajaran langsung oleh profesional di bidangnya dan mencakup berbagai topik dari dasar-dasar bahasa hingga strategi bisnis digital. Hasil dari program ini menunjukkan tingkat kepuasan yang tinggi di kalangan peserta, dengan peningkatan signifikan dalam keterampilan bahasa dan pengetahuan bisnis mereka. Evaluasi lebih lanjut menunjukkan keberhasilan program dalam meningkatkan keterampilan peserta, dengan beberapa rekomendasi untuk perbaikan di masa depan guna lebih mengoptimalkan kontribusi asisten pengajar dan pemenuhan harapan peserta. Program ini diharapkan dapat berkontribusi pada peningkatan ekonomi lokal dan hubungan internasional antara Indonesia dan Korea Selatan.
IMPLEMENTASI IoT UNTUK SISTEM IRIGASI DI PONDOK PESANTREN NURUL HARAMAIN, NARMADA, LOMBOK BARAT
Authors: Widiartha Ida Bagus Ketut , Anjarwani Sri Endang , Albar Mohammad Ali , Ratnasari Dwi , Alamsyah Noor , Kusuma Pande Permadi , Ayoedya Jasmine Nabila
Published: September 2024

Pondok Pesantren Nurul Haramain di Lombok Barat menghadapi tantangan dalam pengelolaan air, terutama selama musim kemarau. Meskipun memiliki sumber daya air yang melimpah, metode irigasi manual yang digunakan terbukti kurang efisien. Untuk mengatasi hal ini, sistem irigasi berbasis Internet of Things (IoT) diperkenalkan, disamping untuk mendidik para santri untuk meningkatkan kesadaran akan sumber daya air yang terbatas dan meningkatkan pengetahuan para santri dibidang teknologi IoT. Dengan mengintegrasikan sensor dan perangkat yang terhubung melalui internet, sistem ini mampu meningkatkan efisiensi penggunaan air hingga 30% dan meningkatkan produktivitas pertanian sebesar 20%. Sistem IoT ini memungkinkan pengelolaan air yang lebih tepat waktu dan hemat, serta mendorong kesadaran lingkungan di kalangan santri dan masyarakat sekitar. Implementasi ini juga mengurangi biaya operasional dan kebutuhan tenaga kerja manual, menjadikannya solusi yang berkelanjutan bagi pondok pesantren. Manfaat tambahan dari sistem ini adalah edukasi santri mengenai teknologi dan praktik pengelolaan air yang efisien, diharapkan dapat diterapkan di masa mendatang untuk pelestarian sumber daya air.
PELATIHAN PEMBUATAN MEDIA PEMBELAJARAN INTERAKTIF DI MADRASAH IBTIDAIYAH INTEGRAL BUAH HATI INSANI MATARAM
Authors: Albar Mohammad Ali , Alamsyah Noor , Anjarwani Sri Endang , Ratnasari Dwi , Afwani Royana , Salsabila Raissa Calista
Published: September 2024

Kegiatan pengabdian mengenai pelatihan pembuatan media pembelajaran interaktif di sekolah MI Integral Buah Hati Insani Mataram ini memiliki tujuan untuk meningkatkan keterampilan para guru dalam menggunakan Canva sebagai alat untuk menciptakan materi pembelajaran yang menarik dan efektif karena para guru sebelumnya membuat bahan ajar menggunakan aplikasi Microsoft Power Point. Pentingnya topik ini terletak pada peran penting teknologi dalam pendidikan modern. Canva, sebagai alat desain grafis yang user friendly, memiliki potensi besar untuk memperkaya pengalaman pembelajaran online. Namun, tidak semua individu memiliki pemahaman yang memadai tentang cara menggunakannya secara efektif. Oleh karena itu, pelatihan ini dipilih untuk membekali para guru dengan keterampilan yang relevan dalam pembuatan materi pembelajaran yang kreatif dan interaktif. Metode pelaksanaan pelatihan mencakup sesi teori, demonstrasi praktik, latihan mandiri, dan diskusi. para guru diberikan pemahaman tentang dasar-dasar Canva dan kemudian diarahkan untuk mengaplikasikan pengetahuan tersebut dalam pembuatan materi pembelajaran secara mandiri. Hasilnya adalah peningkatan keterampilan peserta dalam desain grafis, yang dapat diterapkan dalam konteks pendidikan mereka. Kegiatan ini memiliki dampak yang luas, termasuk peningkatan kualitas pembelajaran online dan dukungan pengembangan sumber daya pendidikan yang lebih baik. Hasil positif dari pelatihan ini menggaris bawahi pentingnya penggunaan teknologi dalam pendidikan modern dan memberikan landasan untuk penelitian lebih lanjut dalam pengembangan metode pembelajaran yang inovatif dan efektif. Respon positif dari sekolah MI Integral Buah Hati Insani Mataram diindikasikan melalui kuesioner online yang dibagikan setelah kegiatan pelatihan berakhir dengan jumlah responden sebanyak 11 orang.
SISTEM INFORMASI DINAS KELAUTAN DAN PERIKANAN KABUPATEN DOMPU PROVINSI NUSA TENGGARA BARAT BERBASIS WEBSITE MENGGUNAKAN FRAMEWORK BOOTSTRAP DAN CODEIGNITER
Authors: Munirah Zahrahtun , Murpratiwi Santi Ika , Ramlah Ramlah
Published: September 2024

Dinas Kelautan dan Perikanan Kabupaten Dompu Provinsi Nusa Tenggara Barat adalah lembaga pemerintah yang bertanggung jawab atas pengelolaan, pengembangan, dan perlindungan sumber daya kelautan dan perikanan. Salah satu peran pentingnya yaitu mengkoordinasikan kegiatan pengelolaan sumber daya kelautan dan perikanan, termasuk penangkapan ikan yang berkelanjutan, pengembangan budidaya perikanan serta pelestarian lingkungan laut. Saai ini Kelautan dan Perikanan sudah memiliki website company profile untuk menyajikan informasi terkait kantor tersebut, akan tetapi website tersebut memiliki fitur-fitur yang kurang lengkap seperti tidak adanya foto-foto dari unit kerja dari seluruh pegawai yang bekerja serta tidak adanya sistem validasi oleh Kapala Bidang pada saat admin menginputkan berita. Dengan dibuatnya sistem informasi ini, dapat memberikan aksesibilitas informasi kepada masyarakat terkait dengan layanan, program, kebijakan, dan kegiatan yang diselenggarakan oleh Dinas Kelautan dan Perikanan Kabupaten Dompu Provinsi Nusa Tenggara Barat.
The Role of Driving Actors as Social Engineers in Improving the Community's Economy through Social Entrepreneurship in Marine Ecotourism
Authors: Alamuiza Monica Ihsan , Yulhendri Yulhendri , Fahmi Zul
Published: September 2024

The gap initiated the movement of empowerment through social entrepreneurship as a business effort to improve the economy of the community in the Sungai Pinang area by a driving actor named Ricky with a learning center known as Ricky's beach house. This research was conducted at Ricky's beach house in the Sungai Pinang marine tourism area with an inductive research approach with a descriptive qualitative method of field study method. This research presents data using descriptive data. This research aims to analyze the role of driving actors in improving the community's economy through social entrepreneurship and marine ecotourism. The results of this study show that the development steps taken by Ricky's beach house by empowering the potential of the surrounding community to be involved in every aspect of the development of Sungai Pinang tourism, such as utilizing people's homes as tourist lodging facilities, turning people into tour guides, and using facilities owned by other residents such as boats for tourists who want to go to the island including at the same time being the captain of the ship, being a waiter at the bar and lounge. The concept of social entrepreneurship also emphasizes the concept of ecotourism where tourism that is developed still pays attention to environmental sustainability even by involving foreign tourists as volunteers.
Study of the Specificities of Thinking in Chemistry Education within the Science Education Cluster
Authors: Husna Nisyya Syarifatul , Hernani Hernani , Mudzakir Ahmad
Published: September 2024

The aim of this research is to explore the concept of systems thinking in relation to the specificities of systems thinking in science education by conducting a content analysis of studies published between 2010 and 2020. Most of the articles were published between 2017 and 2019. This study employs a descriptive content analysis method on 40 articles about systems thinking in science, utilizing a literature review of international articles. The instruments used include a content analysis format created by the researcher and two expert researchers. Doubtful data were discussed holistically in relation to the content analysis. The results of the research reveal the specificities of systems thinking within the science field. In the realm of chemistry, a systems-based approach through the integration of green chemistry and systemic synthesis questions has proven effective in enhancing systems thinking skills and awareness of sustainability. The application of molecular sustainability principles in chemistry education can lead students to complex thinking, with an understanding of chemistry linked to various systems such as social, economic, and environmental contexts, fostering a holistic understanding. Integrating systems thinking approaches in science education can enhance students' comprehension of the complexities of the real world and equip them with the necessary skills to address increasingly dynamic and interconnected global challenges. The practical implications of these findings highlight the importance of developing a systems-oriented curriculum to support more comprehensive and integrative learning
Sistemas Fluviais
Authors: Paz Otacílio Lopes de Souza da
Published: September 2024

Se, por um lado, a obra reúne temas que abordam os impactos ambientais e o transporte rodovia rio de produtos perigosos, que podem ter consequências devastadoras para os sistemas fluviais, explorando os impactos ambientais resultantes desses eventos e possíveis estratégias de mitigação, por outro, mostra que e possível a recuperação de áreas degradadas em áreas rurais, equilibrando a produção com a conservação. A aça o humana tem desempenhado um papel significativo nos problemas ambientais, que tem sido cada vez mais frequente e intenso, sobretudo, nos ambientes urbanos, em decorrência das mudanças clima ticas, sendo essencial que os governos implementem políticas publicas eficazes para mitigar os impactos ambientais e um olhar atento dos tomadores de decisões. Cada seção, cada capítulo, representa uma jornada u nica e essencial para a compreensão dos meandros da ciência geográfica, que sao cuidadosamente apresentados ao longo de toda a obra!
Towards a Mexican School of General Analytical Chemistry
Authors: Rojas-Hernández Alberto , Ramírez-Silva María Teresa , Galano Annia
Published: September 2024

This year the 50th anniversary of the Metropolitan Autonomous University is celebrated. It is for this reason that the JMCS decided to publish a special issue with contributions from professors from the Department of Chemistry. We thank the Editorial Committee of the issue for the invitation to write an article about the academic work that has been done in the Analytical Chemistry Area of this Department. We hope that we have managed to give a good description of the achievements we have had since the Analytical Chemistry Area was founded in the Iztapalapa Unit of the Metropolitan Autonomous University.
 
Resumen. En este año se celebra el 50 aniversario de la Universidad Autónoma Metropolitana. Es con ese motivo que el JMCS decidió publicar un número especial con contribuciones de profesores del Departamento de Química. Agradecemos al Comité Editorial del número la invitación para hacer una contribución acerca del trabajo académico que se ha hecho en el Área de Química Analítica. Esperamos que hayamos logrado dar una buena descripción de los logros que hemos tenido desde que se fundó el Área de Química Analítica en la Unidad Iztapalapa de la Universidad Autónoma Metropolitana.
Comunicação em Saúde no Instagram da Prefeitura do Rio de Janeiro: análise das estratégias da vacinação contra a covid-19
Authors: Petra Priscila Cardia , `Paiva Ester , Almeida Celita , Vieira Flávia , Fernandez Michelle , Matta Gustavo
Published: September 2024

Esta pesquisa pretendeu analisar a forma com a qual a Prefeitura do Rio de Janeiro utilizou o Instagram para comunicação em saúde nos cinco primeiros meses da vacinação contra a covid-19. Utilizou-se a análise de conteúdo de 148 publicações selecionadas do Instagram da Prefeitura e, dessa análise, emergiram duas categorias. Verificou-se que a Prefeitura do Rio de Janeiro diversificou recursos para divulgar a campanha de vacinação, procurando estimular a confiança vacinal por meio da interatividade com os usuários e enfatizando personalidades e locais históricos da cidade. Constatou-se que a Prefeitura do Rio de Janeiro adotou estratégias tradicionais e informacionais para a referida campanha de vacinação e buscou utilizar as ferramentas da plataforma digital para amplificá-la. Ao final, discutem-se as limitações da utilização das redes sociais por entes e órgãos estatais e como estabelecer diálogos com os princípios do Sistema Único de Saúde.
O status da desconfiança: reflexões sobre a controvérsia hesitação vacinal e a covid-19
Authors: Oliveira Vick Brito , Bezerra Adriana Falangola Benjamin , Oliveira Sydia Rosana de Araújo
Published: September 2024

Os conflitos e a discordância entre porta-vozes na pandemia da covid-19 centralizaram o debate sobre a desconfiança da vacina da covid-19 no Brasil. O status de desconfiança intensificou a problemática da hesitação vacinal para o Programa Nacional de Imunizações. Este ensaio propõe a aproximação entre uma perspectiva metodológica, alicerçada na Teoria Ator-Rede, e a temática, sugerindo a cartografia da controvérsia como ferramenta para investigação. A discussão centrou-se no complexo fenômeno da hesitação vacinal, ressaltando que ele não se supera com o ato de se vacinar, e exige da política pública de saúde a recuperação da confiança na vacinação, especialmente diante de possíveis novos estados de emergência em saúde pública. Nesse sentido, o ensaio ressalta as ligações entre atores da hesitação vacinal e suas ações e sugere o desenho de uma rede para a proliferação da hesitação vacinal entre os anos 2021 e 2022.
Cuidados-em-interação: práticas, saberes e reflexividade na saúde
Authors: Lisboa Marcia Rodrigues , Binet Michel
Published: September 2024

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Deputy editor-in-chief’s preface to Issue 4, 2024
Authors: Rychkova L. V.
Published: September 2024

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Cytokine imbalance as a factor of postoperative complications of third mandibular molar extraction
Authors: Glushkova M. I. , Seminskiy I. Zh. , Alyoshkin I. G.
Published: September 2024

Background. Tooth extraction is considered the most frequently performed operation in surgical dentistry, which can often cause inflammatory complications. Modern research has come a long way in terms of developing methods for the prevention, diagnosis and treatment of these complications, but the search for their early laboratory markers remains an urgent task to this day.

The aim of the study. To determine prognostic laboratory criteria for the development of local inflammatory complications of third mandibular molar extraction.

Methods. The study included 35 people who underwent extraction of a third mandibular (semi-impacted) molar. Before the surgery, immediately after the surgery, 1, 2, 3 and 4 days after the surgery, we assessed the objective status of the patients and collected oral fluid from the oral cavity, in which we determined the concentrations of cytokines using enzyme-linked immunosorbent assay. After the surgery, patients were divided into a control group and a group with complications with determination of their cytokine status.

Results. Immediately after the surgery, patients from the group with complications, compared with patients from the control group, had significantly higher levels of proinflammatory cytokines – interleukin (IL) 1, IL-8 and comparable levels of tumor necrosis factor α and anti-inflammatory cytokines IL-4 and IL-10. Integral cytokine indices in both groups showed a sharp shift towards pro-inflammatory direction in patients with complications. This fact determines the protracted or progressive nature of the inflammatory process after the surgery.

Conclusion. Determining the level of individual cytokines and cytokine indices in the oral fluid after the extraction of a third mandibular molar allows us to identify early markers for the chronicity of the inflammatory process, to predict its further course and to take appropriate measures to prevent the development of expected complications.
Current ideas on the pathogenesis of osteoporosis in chronic lymphatic leukemia (literature review)
Authors: Osikov M. V. , Korobkin E. A. , Fedosov A. A. , Sineglazova A. V.
Published: September 2024

Background. Chronic lymphocytic leukemia (CLL) is the second most common hematological malignancy without a trend towards a decrease in its incidence. 66 % of patients with CLL experience bone fractures as a result of osteoporosis in all age groups, and the detection frequency is no more than 15 %. Insufficient understanding of the osteoporosis pathogenesis in CLL leads to problems in diagnosis, prevention and therapy.

The aim of the study. To analyze modern data on the features of the osteoporosis pathogenesis in chronic lymphocytic leukemia.

Results and discussion. Osteoporosis is formed when osteoresorption prevails over osteosynthesis due to intercellular interactions of bone tissue and the immune system, dysregulation of intracellular signaling pathways RANKL/RANK/OPG, Wnt, FoxO, RUNX2, initiated by cytokines, growth factors, prostaglandins, and hormones. The degree of osteoresorption in CLL is associated with the severity of the clinical course, chemotherapy and hormonal deprivation. The osteoporosis pathogenesis in CLL is considered as part of a complex set of events, including, firstly, the interaction between leukemic cells (overexpression of PTHrP, RANKL) and bone cells (synthesis of growth factors), which forms a vicious circle of osteoresorption and tumor growth. Secondly, pro-inflammatory markers in CLL (tumor necrosis factor α, interleukin (IL) 1β, IL-6, IL-8, IL-11, granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, transforming growth factor β, prostaglandin E2) limit osteoblast-induced osteosynthesis and stimulate the expansion of osteoclasts from monocytic suppressor cells of myeloid origin with or without the participation of the RANKL/RANK system. Thirdly, oxidative stress in CLL and impaired efficiency of antioxidant protection with the participation of fibroblast growth factor 23, transcription factor Nrf-2 with activation of JNK, ERK1/2, NF-κB, and also an increase in the RANKL/OPG ratio lead to inhibition of osteoblastogenesis.

Conclusion. Analyzing and systematizing data on the osteoporosis pathogenesis in CLL are instrumental for the development of diagnostic criteria for osteoporosis in chronic lymphocytic leukemia that are much-needed in clinical practice and for the improvement of therapeutic tactics.
Correction of professional burnout of health workers in the process of mindfulness-based training
Authors: Popova K. M. , Kuzmin M. Yu.
Published: September 2024

Background. The article reviews the problem of testing the in-person version of the burnout reduction program "OsNOVA" for health workers.

The aim of the work. To present the results of the program immediately after its completion and to study the sustainability of the effect.

Materials and methods. As part of the program testing, 49 doctors and nurses were interviewed. The following methods were used: Maslach Burnout Inventory; Lazarus and Folkman Inventory of Coping Strategies; Beck Depression Inventory; Perceived Stress Scale 10; Short Form 12 questionnaire; mindfulness questionnaires.

Results. It was found that when implementing a program to reduce the level of professional burnout in medical workers, held in-person, there is a statistically significant decrease in those subjects whose burnout was initially high. This is accompanied by an increase in mindfulness (primarily such components as Non-judgmentalism, Observation and Awareness of Actions), productive coping strategies. Health workers with a relatively low level of burnout had an improvement in a number of indicators reflecting the burnout level, as well as an increase in the quality of life. The effect achieved by the program persisted for at least three months after the end of its active part.

Conclusion. The "OsNOVA" program in an in-person format can be used to prevent professional burnout of health workers. Additional work is planned for its further improvement.
Saúde mental de pessoas em tratamento oncológico acompanhadas por uma associação de apoio: um relato de experiência de acadêmicos de medicina
Authors: Rosset Camila de Vargas , Santos Nathally Neri dos , Santos Elitiele Ortiz dos
Published: September 2024

O presente estudo tem por objetivo apresentar a experiência de acadêmicas do curso de Medicina durante as práticas de estágio realizadas em uma instituição de Apoio a Pessoas com Câncer de um município da fronteira oeste do Rio Grande do Sul. A experiência consiste em atividades práticas e de extensão vinculadas ao Componente Curricular de Saúde Coletiva I do curso de Medicina de uma universidade localizada na fronteira oeste do Rio Grande do Sul. A instituição tem características internas de uma casa, com 24 acomodações para usuários que realizam tratamento oncológico e seus acompanhantes. As atividades foram realizadas no período de 05 de maio a 05 de junho de 2022, representando uma carga horária total de 20 horas. Durante a observação participante, identificou-se a importância da humanização e da valorização das individualidades dos usuários promovida pelos profissionais, por meio da criação de vínculos, do estímulo à socialização e do desenvolvimento de atividades dinâmicas e criativas, que promovem a saúde da mente e do corpo, dadas as limitações do diagnóstico oncológico. Para a realização da atividade de extensão, utilizaram-se ferramentas da musicoterapia, a fim de proporcionar aos usuários momentos de descontração, diálogo e, principalmente, de desconexão com a atmosfera pesada e limitante agregada ao diagnóstico e ao tratamento do câncer. O presente trabalho evidenciou a importância das casas de apoio a pessoas em tratamento oncológico, com foco no cuidado com a saúde biopsicossocial dos usuários e de seus acompanhantes. Além disso, reforça a importância do cuidado em saúde mental das pessoas em tratamento oncológico, sendo as atividades de socialização ferramentas que contribuem para a produção desse cuidado.
Extensão Universitária e distribuição cinematográfica – uma reflexão sobre o Projeto “Trama”
Authors: Silva Sabrina Tenorio Luna da
Published: September 2024

Este artigo tem o objetivo de relatar o processo de criação e desenvolvimento do projeto de extensão “Distribuição cinematográfica: Curadoria, festivais, produção e design de audiência”. O projeto é ligado ao Departamento de Comunicação e à graduação em Cinema e Audiovisual da Universidade Federal de Mato Grosso e tem como objetivo formar profissionais habilitados a trabalhar na área de distribuição, um dos maiores gargalos da produção cinematográfica nacional.
Validation of Downhole Fluid Analysis and Machine-Learning Compositional Determination
Authors:   SLB, Andrews A. Ballard , Sullivan Matthew ,   SLB, Deger Evgeniya ,   SLB, Hakim Bilal ,   TALOS, Messonnier Tom ,   TALOS, Thibodeaux Brandon ,   TALOS, Mahmmodaghdam Elham ,   SLB, Jackson Richard ,   SLB, Taylor Shawn David ,   SLB, Mullins Oliver C. ,   SLB
Published: September 2024

Downhole fluid analysis (DFA) relies on accurate in-situ composition and gas-oil ratio (GOR) derived from vis-near infrared optical spectra. New advanced optical spectrometers have been introduced into the field on a new wireline formation testing platform. In this report, measurements of live crude oils collected with a research-grade spectrometer are compared with the same samples using DFA tools and logs. In addition, spectral interpretation using advanced machine-learning algorithms is shown to yield the same composition of C1 to C6+ as obtained from PVT reports within an absolute error bar of 1% and GOR within a relative error bar of 15%. Data are shown from three separate crude oil samples with excellent matching of laboratory and downhole spectra. Machine-learning algorithms are employed to train the calibration model on a large library of light to heavy oils, gas condensates, and gases. More specifically, factor analysis replaces the original variables with linear combinations of new variables that best capture the spectral variations relevant for predicting the compositions. The optimal preprocessing and regression algorithms are determined through cross validation on the training-validation splits. The spectra acquired downhole on live oil samples are shown herein to be identical to spectra obtained on the same samples under reservoir temperature and pressure conditions in the laboratory using a high-resolution optical spectrometer (with discretized spectra to match downhole spectrometers). In addition, the compositional predictions from the spectral analysis are compared with PVT reports of these samples. Methane (C1), ethane (C2), propane (C3), butane (C4), and pentane (C5) and carbon dioxide (CO2) are predicted with absolute accuracies of ±1 wt% and higher carbon numbers (C6+) with absolute accuracy of ±2 wt%. An artificial neural network (ANN) is trained on a large PVT and gas chromatography (GC) database to a relative accuracy of ±15% scf/bbl. Excellence in spectroscopy and machine-learning algorithms provide new value in DFA tools and interpretation, which together establish new frontiers in wireline logging. These enhanced capabilities of fluids measurement and interpretation extend the capability of reservoir evaluation, especially through reservoir fluid geodynamics (RFG).
Development of Artificial Intelligence-Based Programs for the Diagnosis of Myocarditis in COVID-19 Using Chest Computed Tomography Data»
Authors: Nastenko Ievgen A. , Honcharuk Maksym O. , Babenko Vitalii O. , Lynnyk Mykola I. , Ignatieva Viktoria I. , Yachnyk Vitalii A.
Published: September 2024

It has been established that 7.2% of patients hospitalized with coronavirus disease (COVID-19) exhibit signs of heart disease, with 23% of these patients experiencing heart failure. Currently, there is a lack of data on chest computed tomography (CT) for diagnosing myocarditis associated with COVID-19.
The aim. To justify the feasibility and develop classification models for diagnosing myocarditis in COVID-19 patients based on chest CT data processing.
Materials and methods. A retrospective analysis of data from 140 COVID-19 patients was conducted. Chest CT scans were analyzed using DRAGONFLY software, with permission from Object Research Systems. The COVID-CT-MD database, which includes CT data from 169 confirmed cases of SARS-CoV-2 infection, was used to build classification models. The regions of interest were fragments of heart CT images. Texture analysis methods were employed to create diagnostic models.
Results. It was shown that the average density of the myocardium of a patient with a confirmed diagnosis of SARS-CoV-2 infection according to the Hounsfield scale does not essentially differ from the densitometric indicators of a healthy person. Therefore, the research was focused on finding structural changes in CT images for their use in constructing diagnostic models.
The use of different classification algorithms had little effect on classification accuracy, probably due to the informational content of the input data. However, the obtained accuracy of the diagnostic models is acceptable and allows them to be used to support medical decision-making regarding diagnosis and treatment.
Conclusions. Using classic methods, myocarditis was diagnosed in 7.1% of patients with severe pneumonia caused by the coronavirus. The global data closely aligns with the results of our clinical studies. The obtained results allowed for assessing structural changes in the myocardium characteristic of the acute form of SARS-CoV-2 infection. The constructed classification models indicate that specific changes in the myocardium during the acute form of SARS-CoV-2 infection can be identified using CT. The highest diagnostic accuracy on test samples reached 74%. The implementation of the developed diagnostic programs based on texture analysis of CT data and artificial intelligence technologies enables the diagnosis of myocarditis and the assessment of long-term treatment efficiency. Creation of these diagnostic programs using artificial intelligence technologies significantly simplifies the work of radiologists and improves the efficiency of myocarditis diagnosis in patients with SARS-CoV-2 infection.
Cytokine Storm in Pathogenesis of COVID-19 Complications
Authors: Rasputniak Olga V. , Gavrilenko Tetiana I. , Pidgaina Olena A. , Shnaider Liudmyla M. , Lomakovskyi Oleksandr M. , Kalashnikov Sviatoslav A.
Published: September 2024

The aim. To explore the current literature and key findings concerning the cytokine storm contribution to pathogenesis of COVID-19 complications and mortality, and summarize clinical and pathologic features of cytokine storm in COVID-19 patients.
A cytokine storm is a hyperinflammatory state secondary to excessive production of cytokines by deregulated immune system. It manifests clinically as an influenza-like syndrome, which can be complicated by multi-organ failure and coagulopathy, leading in most severe cases even to death. Cytokine storm has recently emerged as key aspect in COVID-19 disease, as affected patients show high levels of several key pro-inflammatory cytokines, some of which also correlate with disease severity.
The current review describes the role of critical cytokines in COVID-19-mediated cytokine storm. Key findings of the studies are provided further. A cytokine storm is associated with COVID-19 severity and is also a crucial cause of death from COVID-19. Impaired acquired immune responses and uncontrolled inflammatory innate responses may be associated with the mechanism of cytokine storm in COVID-19. Cytokine storm is defined as acute overproduction and uncontrolled release of pro-inflammatory markers, both locally and systemically. In COVID-19 patients, pyroptosis triggers the release of proinflammatory cytokines and affects macrophage and lymphocyte functions, causing peripheral lymphopenia. Cytokine storm is characterized by a clinical presentation of overwhelming systemic inflammation, hyperferritinemia, hemodynamic instability, and multi-organ failure. The cytokine storm clinical findings are attributed to the action of pro-inflammatory cytokines like interleukin-1, interleukin-6, tumor necrosis factor alpha, vascular endothelial growth factor.
The Efficacy of a Home-Based, Augmented Reality Dual-Task Platform for Cognitive-Motor Training in Elderly Patients: A Pilot Observational Study
Authors: Yoon Bora , Park Jihye , Shim YongSoo
Published: September 2024

Objective This study introduces a novel home-based dual-task platform incorporating augmented reality (AR), COGNIMO, aimed at simultaneously enhancing cognition and physical abilities. The purpose of this study was to assess the effectiveness of this intervention in enhancing cognitive and physical abilities in elderly individuals with subjective cognitive decline, mild cognitive impairment (MCI), and mild Alzheimer’s dementia.Methods A 12-week observational study enrolled 57 participants aged 60–85 years. Primary outcomes included changes in cognitive scores (Korean Mini-Mental State Examination, 2nd edition [K-MMSE-2] and Korean-Montreal Cognitive Assessment [K-MoCA]), while secondary outcomes measured physical parameters and depression scores between baseline and week 12 in the active and the control groups.Results Of 57 participants, 49 completed the study. The active group (≥12 sessions) exhibited significant improvement in K-MoCA compared to the control group (<12 sessions) (p=0.004), while K-MMSE-2 score changes showed no significant difference (p=0.579). Positive correlations between training sessions and K-MoCA changes were observed (r=0.31, p=0.038), emphasizing a dose-response relationship. Subgroup analyses revealed a distinction in cognitive changes, particularly in the MCI group.Conclusion The COGNIMO platform showed positive effects on cognitive function in MCI patients, suggesting potential benefits for this population. The study highlights the potential of AR-integrated home-based interventions for cognitive enhancement in elderly individuals, underlining the need for further trials in the future.
Start-up Değerlemesi: Yeni bir Yöntem Önerisi
Authors: Tutar İbrahim , Orbey Özge
Published: September 2024

Bu araştırma, Türkiye’de yeni kurulan teknoloji ve yenilik odaklı fikir aşamasındaki girişimlerin (start-up’ların) değerlemesinde kullanılacak yeni bir yöntem geliştirmeyi amaçlamaktadır. Bu çalışma, start-up’ların fikir veya projelerinin ölçeklenebilirliği, ekibinin niteliği, kurucuların sayısı, ekibin eğitim dereceleri, yatırımının içinde bulunduğu endüstri gibi bazı değişkenleri test etmek suretiyle, değerlerini etkileyen etmenlerin neler olduğunu; bulunan bu etmenlerin değeri ne kadar etkilediğini ve değerlemede işe yarayacak yeni bir yöntem geliştirmeyi amaçlamaktadır. Türkiye’de 2022-2023 döneminde kitle fonlama platformları (KFP) üzerinden tohum aşamasında satılan ya da girişim sermayesi yatırım fonları (GSYF) tarafından birinci turda payı satın alınan start-up’ların yataykesit verilerinin ve Cobb-Douglas üretim modelinin kullanıldığı bu çalışmada, normal en küçük kareler regresyon analiziyle söz konusu start-up’ların değerleri tahmin edilmiştir. Araştırma sonuçları, Türkiye’deki KFP’lerce fonlanan tohum işletmelerin hisselerinin değerleri için yüksek teknolojinin ve proje ekibinin eğitim derecelerinin önemli bir etkiye sahip olduğunu; GSYF’lerin satın aldığı start-up’lar için yapılan değerlemelerde ise, start-up’ların yüksek teknolojiye ve ölçeklenebilirlik özelliklerine sahip projelerinin nispeten daha yüksek etkiye sahip olduğunu göstermektedir. Araştırma sonucu, ABD gibi gelişmiş ülkelerdeki start-up değerlemesinde kullanılan Berkus, puankartı değerleme yöntemi veya risk faktörlerini toplama yöntemi gibi değerleme yöntemlerindeki değer katsayılarının Türkiye’ye uygulanması halinde, çok gerçekçi sonuçlar alınmayacağını; her ülkedeki şirketlerin değer katsayılarının farklı olabileceğini göstermektedir.
Kamu Çevre Koruma Harcamalarının Atık Emisyonuna Etkileri: Büyükşehir Statüsündeki Mahalli İdareler Temelinde Bir İnceleme
Authors: Taşdoğan Bilgen
Published: September 2024

Bu çalışmada “ortak finansman ilkesi” temelinde çevre koruma harcamaları üzerinde durulmaktadır. Türkiye’de toplam çevre koruma harcamaları içinde özel sektörün payı kamuya göre daha fazladır. Fakat, çevrenin kamusal mal kabul edilmesi ve çevre kirliliğinin yarattığı dışsallık piyasa mekanizması ile azaltılmamaktadır. Yürürlükteki mevzuatlar gereği kamunun yaptığı çevre koruma harcamalarının büyük oranda belediyeler tarafından gerçekleştirilmektedir. Bu noktayı ele alan çalışma, 2013-2021 dönemi için 30 büyükşehiri iki alt gruba ayırarak analiz etmektedir. 2012 yılı öncesi büyükşehir statüsü kazanan 16 il ve 2012 sonrası büyükşehir olan 14 ilin değerlendirilmesinden elde edilen bulgulara göre; 16 il mahalli idaresinin atık emisyonunu azaltabilmek için atık yönetimi harcamalarına ek olarak toprak, yeraltı ve yüzey sularının korunması ve kalitesinin iyileştirilmesi harcamalarına da daha fazla kaynak ayırarak atık emisyonunun azaltılmasına daha fazla katkı sağlamaktadır. 2012 yılı sonrası büyükşehir statüsü kazanan 14 ilde yapılan atık emisyonunun azaltılmasına yönelik kamu harcamalarının atık emisyonlarını azaltıcı etkisinin, 16 ile göre daha düşük olduğu tespit edilmiştir. Dolayısıyla kamu kaynaklarının daha etkin kullanımı ve çevre kirliliğini önleme çalışmalarının daha verimli olması için, 14 belediyenin atık yönetimi uygulamalarını ve emisyonu azaltıcı tedbirlerini, 16 ildeki uygulamaları takip ederek iyileştirmesi gerekmektedir.
Relationship Between Financial Development and Carbon Emissions: Empirical Evidence from Türkiye with Fractional Frequency Fourier Approaches
Authors: Ergün Tatar Havanur , Çeştepe Hamza
Published: September 2024

Abstract
This study empirically analyzes the relationship between carbon emissions, one of the most important indicators of environmental pollution, and financial development. Using data from Türkiye for the period 1995-2019, the fractional frequency Fourier ADL cointegration method -previously unused in similar studies- is employed for the analysis. The results, which also account for economic growth, demonstrate a cointegration relationship between the variables. Additionally, the FMOLS method is utilized for model estimation, concluding that financial development and growth lead to increased carbon emissions. The study suggests that loans provided to the financial sector should be directed towards technological investments that reduce carbon emissions