bluuebunny/crossref_metadata_2025 huggingface dataset:
Socio-ecological significance of urban green space under a changing climate: Perspectives and concerns of young adults in Germany
Authors: BOTAH Kwadwo Yeboah
Published: February 2025

n the context of accelerated urbanization and climate change, urban green spaces
(UGS) are highly considered an essential pillar of a livable city that promotes a healthier
environment and enhances human socio-ecological needs. In this light, several studies have
examined public perceptions of the health effects of UGS for informed urban planning. This study
supports this field by employing a web-based questionnaire survey to explore the perspectives
of young adults in Germany on the health potentials of UGS, their climate change impact
awareness as well as any existing concerns as they utilize these spaces, particularly in the context
of climate change. The results show that young adults in Germany irrespective of their level of
concern and awareness of climate change impacts overwhelmingly recognize and appreciate the
positive health and well-being impacts of UGS and their growing importance in the context of
climate change. In general, higher affinity was placed on the mental health benefits of UGS,
however under climate change conditions, greater affinity was given to ecological benefits.
Likewise, UGS's role in temperature regulation was perceived as the most increasingly important
now and under climate change conditions. However, poor cleanliness, safety, security, and noise
were major concerns. Several demographic factors that influenced respondents' awareness,
perceptions, and concerns were revealed. Ultimately, the study concludes that UGSs are highly
valued but a segment of the population lacks awareness of or underestimates its health effects.
Hence, it echoes the critical need for extensive public education on climate change impacts and
the health benefits of UGS while also emphasizing the importance of incorporating the
perspectives and concerns of young residents into the planning and design of these spaces to
advance their sustainability, resilience, and multifunctionality in the face of climate change.
The role of the Active Interventions in the atmosphere in the context of climate change
Authors: ILIE Nicolae , AXINTE Aurel-Dănuț , CREȚU Ștefănel-Claudiu , Beteringhe Andreea
Published: February 2025

Releasing a significant amount of greenhouse gases into the atmosphere, such as
carbon dioxide and methane, we expect to see more severe extreme weather phenomena with
harmful effects on society and economic activities. To suppress or mitigate the damages due to
extreme weather phenomena, besides framework directives that impose a lowering or complete
removal of the greenhouse gases, by interest many programs about active interventions in the
atmosphere. These are associated with measures that include hail suppression, rainfall
enhancement, fog dissipation, and mitigating the risks associated with early and late frost
phenomena. In Romania, the main activity linked by Active Interventions in the Atmosphere by
Law 173/2008 is hail suppression by anti-hail rockets technology. In the future, besides hail
suppression, it is desired to enact rain enhancement and uniformity of the rainfall. Based on the
research conducted within U.C.C.G. Moldova 1 Iasi, there was noticed a lowering of the risk
shown by the hailstone once the convective cells were seeded. Also, the clouds seeding with
silver iodide (AgI) have increased rainfall within the protected areas, up 20 to 25% compared
with the neighboring regions. In the future, for rain enhancement at the national level with
aviation technology, importance, the results achieved following the experiments made in the
southeastern part of Romania as a part of ‘The local experimental program at small scale for rain
enhancement in the Banat Region, the western part of Oltenia, and northeastern part of
Romania,’ during the years 2019 and 2021.
Geographical distribution, environmental characteristics and valuation possibilities of the areas that have gained viticulture potential in Romania as a result of climate change
Authors: IRIMIA Liviu Mihai , PATRICHE Cristian Valeriu
Published: February 2025

Climate change leads to the modification of the climatic conditions that have defined
the specific of Romania wine regions. Using a GIS based methodology for evaluating the
viticultural potential of geographical areas, this research reveals: the geographical distribution in
Romania of the areas that acquired viticulture potential during the 1991-2013 time period; the
possibilities of exploiting these areas in relation to the current land use; the grape varieties that
could be grown and the types of wine that could be produced in these areas. According to the
results of this research, during the 1991-2013 time period the total area with viticulture potential
is, at Romanian level, with 25,245 km2 larger than during the 1961-1990 time period. The areas
that acquired viticultural potential are mostly located in the northern half of Romania and at
altitudes exceeding 550 m asl. Analyzed in relation to the type of current land use, from the area
that has acquired viticultural potential, 11,408 km2 are excluded from the possibility of viticultural
use, being occupied by forests, water bodies and industrial and residential constructions. The
difference of 13,837 km2 corresponds to agricultural lands of which 8,700 km2 could be exploited
through viticulture if this would be considered by land owners a more economically efficient
alternative of capitalizing on them.
Influence of Audit Committee, Debt to Equity Ratio, Firm Size, and Audit Tenure on Audit Delay
Authors: Octaviani Vina , Febriyanti Diah
Published: February 2025

This study examines the effect of audit committee, debt to equity ratio (DER), firm size, and audit tenure on audit delay in energy sector companies listed on the Indonesia Stock Exchange (IDX) from 2016-2023. The research sample consisted of 11 companies that met specific criteria, with data analyzed using descriptive tests, normality tests, multicollinearity tests, heteroscedasticity tests, and partial and simultaneous hypothesis tests. The study's results indicate that the audit committee has a significant effect on audit delay, which means that the more audit committee members there are, the less likely an audit delay is. On the other hand, debt to-equity ratio and firm size does not have a significant effect on audit delay. However, audit tenure is proven to have a significant negative effect on audit delay, where the longer the audit tenure, the less likely there is a delay in the audit process. Simultaneously, these four independent variables affect audit delay. The results of this study provide implications that energy sector companies in Indonesia should pay attention to the audit committee's role and audit tenure to speed up the audit process and reduce audit delay
Effect of Cash Turnover, Receivable Turnover and Inventory Turnover on Return on Investment (ROI) at PT. Kimia Farma Tbk
Authors: Hermayani Regitha Aulia , Sumawidjaja Riyandi Nur
Published: February 2025

This study examines the effect of cash, accounts receivable, and inventory turnover on return on investment at PT Kimia Farma Tbk for 2019-2023. The data in the study are secondary data sourced from financial data on the Kimia Farma Website. Statistical analysis techniques include regression testing, correlation, determination, and hypothesis testing. The results showed that Cash Turnover positively and significantly affected Return On Investment. In contrast, Receivables Turnover and Inventory Turnover negatively and significantly affected Return On Investment. Overall, the three ratios are positive and significant to the Return On Investment of PT Kimia Farma Tbk in that period
A LIBERDADE DE LOCOMOÇÃO E O EXERCÍCIO DA ATIVIDADE POLICIAL NA RECENTE INTERPRETAÇÃO DOS TRIBUNAIS SUPERIORES
Authors: Beggiora Jr. Jose Luiz
Published: February 2025

O presente artigo teve por objetivo analisar a jurisprudência recente do Supremo Tribunal Federal (STF) e Superior Tribunal de Justiça (STJ) sobre a restrição da liberdade de locomoção, nos casos de abordagem policial e consequente busca pessoal e veicular em face da fundada suspeita. Serão apresentados vários temas de índole prática para o exercício da atividade do profissional de segurança pública, destacando-se os casos em que há divergência entre os Tribunais, notadamente os casos de nervosismo apresentado pela pessoa em determinados contextos e os envolvendo denúncia anônima. Além da fundada suspeita, serão abordados temas correlatos e com aplicação na atividade policial.
Optics of Jumping Sundogs
Authors: Tufaile Alberto , Tufaile Adriana Pedrosa Biscaia
Published: February 2025

Jumping sundogs, or crown flashes, are a rare and interesting atmospheric phenomenon characterized by beams of light dancing across the sky. Despite their rarity, social media videos have captured numerous instances of this phenomenon under seemingly similar conditions. By analyzing these videos, we have investigated the structure and dynamics of jumping sundogs. Our analysis reveals that these events require specific ice crystal types and atmospheric conditions. The distinctive feather-like luminescence of jumping sundogs is attributed to the orientation of ice crystals influenced by electric fields within the cloud. These crystals interact with sunlight, creating the observed luminous pattern. We propose that electrical charges near the base of the crown flash generate an electric field that guides the ice crystal orientation. Jumping sundogs might exhibit a “memory effect”, because in a certain temperature range, their orientation could depend on their past state (aligned), unlike the random orientation at higher temperatures. Jumping sundogs are a type of critical phenomena, where ice crystals align in a specific direction below a critical temperature and orient randomly above it.
 
Received: 21 October 2024 | Revised: 11 December 2024 | Accepted: 24 January 2025
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
List of jumping sundogs videos at https://www.researchgate.net/publication/381039244_Jumping_Sundogs_List_of_Video. Data are available from the corresponding author upon reasonable request.
 
Author Contribution Statement
Alberto Tufaile: Conceptualization, Methodology, Software, Validation, Formal analysis, Investigation, Resources, Data curation, Writing – original draft, Writing – review & editing, Visualization, Supervision, Project administration. Adriana Pedrosa Biscaia Tufaile: Conceptualization, Methodology, Validation, Formal analysis, Resources, Data curation, Writing review & editing, Visualization, Project administration.
Procurement Process Optimization and Firm Supply Chain Performance: The Mediating Effect of Information Technology Integration
Authors: Issah Ofori , Yeboah Hanson Obiri , Agboyi Rosemary Makafui , Baah Samuel Agyei , Ofori Agyeman
Published: February 2025

Purpose: The main objective of the study was to assess the mediating effect of information technology integration on the relationship between procurement process optimization and firm supply chain performance.
Methodology: The study adopts a quantitative explanatory research design. This design is suitable as it examines the causal relationships between procurement process optimization, information technology integration, and firm supply chain performance. A purposive sampling technique was used to obtain a sample size of 200. The findings of the study indicate a positive and significant direct effect of Procurement Process Optimization on Firm Supply Chain Performance. The findings of the study also demonstrate a strong positive direct effect of Procurement Process Optimization on Information Technology Integration. 
Findings: The findings of the study indicate a substantial positive impact of Information Technology Integration on Firm Supply Chain Performance. The findings of the study finally show the indirect effect of Procurement Process Optimization on Firm Supply Chain Performance mediated by Information Technology Integration.
Unique Contribution to Theory, Policy and Practice: This study advances theory by integrating procurement optimization, IT integration, and supply chain performance, informs policy by advocating for digital procurement reforms, and provides practical insights for firms to enhance supply chain efficiency through technology-driven procurement strategies. The study offers insights into how optimizing procurement processes through IT integration can reduce corruption, inefficiencies, and delays in public procurement systems. The research further provides a roadmap for businesses to integrate procurement processes with supply chain management for greater agility and competitiveness.
To Develop a Weld Temperature Measuring System
Authors: Sinha Akash , Kumar Rahul , Niyaz Samsh , Khanna Pradeep
Published: February 2025

Temperature distribution during any welding process holds the key for
understanding and predicting several important welding attributes like
heat affected zone, microstructure of the weld, residual stress, and
distortion during welding. The metal-inert gas welding temperature in the heat
affected zone was measured with the help of k-type thermocouple wire. The
thermocouples junctions were made with the help of a soft arc of carbon arc
welding. These junctions (hot junctions) were then embedded into the
workpiece through brazing at progressively increasing distance from the weld
line so as to record the variation of temperature with respect to distance from
weld center line. The thermocouple wire was connected to a circuit at the
Sunrom thermocouple amplifier. The temperature was measured on Arduino
serial plotter. The temperature found during MIG welding were in good
agreement with the expected temperature at the specified distance for a
particular set of conditions.
АЙМАҚТЫҚ ЭКОНОМИКАЛЫҚ ЫНТЫМАҚТАСТЫҚТАҒЫ ҚЫТАЙ МЕН ҚАЗАҚСТАННЫҢ МҮДДЕЛЕРІ
Authors: Асхат Г. , Қуантай А.Қ.
Published: February 2025

Соңғы жылдары Қытай Халық Республикасы әлемдік және аймақтық нарықтардағы маңызды экономикалық аймақ мәртебесіне ие. ҚХР Қазақстанның негізгі сауда-экономикалық әріптестерінің бірі болып табылады және ҚР экономикасына басты инвесторлардың қатарына кіреді. Соңғы уақыттағы қаржы дағдарысына, сондай-ақ COVID-19 пандемиясы аясында болып жатқан әлемдік экономикадағы құлдырау туралы пессимистік жаңалықтарға қарамастан, Қазақстан мен Қытай арасындағы сауда-экономикалық ынтымақтастық оң көрсеткіштерді көрсетуін жалғастыруда.
Алайда, Қытаймен қарым-қатынас туралы сөз болғанда, көбінесе экономиканы әртараптандыру және арзан ақша табу сияқты артықшылықтарға баса назар аударылатынын және ықтимал қауіптерге жеткілікті көңіл бөлінбейтінін де аңғаруымыз керек. Халықтың мүддесі – мемлекеттің мүддесі болып табылғандықтан, мұндай қарым-қатынастар барысында туындайтын халықтың бірқатар үрейлері негізсіз болып табылмайды және толықтай зерттеліп, қарастырылуды қажет етеді. Мұндай сын-қатерлердің шығу себебін анықтау үшін, әр тараптың, яғни ҚР мен ҚХР-дың жеке мүдделерін зерттеу, аталмыш мүдделердің тоғысатын нүктелерін анықтау маңызды болып табылады.
Осыған орай, зерттеудің басты мақсаты ҚР мен ҚХР арасындағы ынтымақтастық бойынша сұрақтарды екі мемлекеттің мүдделерін де ескере отырып зерттеу болып табылады. Мақсатқа жету үшін зерттеу барысында келесі міндеттер: Қазақстан-Қытай қарым-қатынастарының қазіргі жағдайын бағалау; ынтымақтастықтағы әр мемлекеттің жеке мүдделерін анықтау; мұндай байланыстарды дамытуға бағытталған нақты жобаларды зерттеп, олардың әр тарап мүдделерін қаншалықты қанағаттандырып жатқанын бағалау; Қытай-Қазақстан қарым-қатынастарында туындайтын ҚР және ҚХР алдындағы тәуекелдерді анықтау міндеттері орындалды. Зерттеу нәтижесінде Қытай-Қазақстан ынтымақтастығы, сөзсіз, болуы тиіс, бірақ Қазақстан Республикасының жеке мүдделеріне және халықтың мүдделеріне көбірек көңіл бөлуіміз керек деген қорытынды жасалды
U.S. FOREIGN POLICY IN CENTRAL ASIA: CHALLENGES AND OPPORTUNITIES
Authors: Shukyzhanova A.N , Dinmukhamed U.
Published: February 2025

The paper investigates the relations between the Central Asian republics and the United States of America through the prism of regional and bilateral cooperation. The authors in this article analyzes the trends, challenges and threats of the modern world, the problems of global security and the phenomenon of globalization in the Central Asian region, when all five Central Asian states faced new tasks to determine their place in the international arena, to develop an independent strategic course of development in foreign and domestic policy. The article deals with the current trends in the development of a new paradigm of the theory of international relations, which are relevant in the study of dynamic, global and large-scale processes of change in a constantly changing world and in the Central Asian region. All these areas are relevant both for the US and for the neighboring states of Russia, China and they also need a stable and secure Central Asian region. From the point of view of economic involvement, the US is always looking for new ways to deepen its participation in the region, due to the geopolitical location, internal political structure, cultural and religious characteristics of Central Asia.
«ҒАЛАМДЫҚ ОҢТҮСТІК - ҒАЛАМДЫҚ СОЛТҮСТІК» ГЕОСАЯСИ ҚАҚТЫҒЫСТАР КОНТЕКСТІНДЕГІ БРИКС
Authors: Муминов Н.А. , Ахметова Ш.К
Published: February 2025

Мақала әлемдегі «Солтүстік-Оңтүстік» мәселесін зерттеуге арналған. Авторлар дамыған индустриалды елдер арасындағы айырмашылық жарты шар және оңтүстік жарты шардың ең кедей мемлекеттері «Солтүстік-Оңтүстік» қатынастарының басты ерекшелігі, сонымен қатар автор Солтүстік-Оңтүстік геосаяси қақтығыстарды БРИКС шеңберінде қарастырады.  Оның бүгінгі күнгі ахуалға ықпалы зор екенін атап көрсетеді. Солтүстік пен оңтүстік арасындағы қатынастардың әртүрлілігін арттыру, дамушы елдер аймағындағы аймақтық интеграциялық процестерді кеңейту және әлеуетті аймақтық көшбасшылардың позициясын нығайту мәселелері мақаланың өзектілігін көрсететіні даусыз.
 XXI ғасырда халықаралық қатынастар жүйесін қалыптастыру әлемдік қоғамдастық мүшелерінің жаһандық өзара тәуелділігімен айқындалуда. Елдер арасындағы олардың даму деңгейіне байланысты айырмашылықтар жақын болашақта сақталады. Көптеген қолайсыз елдердің сақталуының салдарын азайту мүмкін болмаса да, соңғы онжылдықтардағы тенденциялар әлемнің дамыған және аз дамыған бөліктері арасындағы қатынастар жаһандық қарама-қайшылықтың жаңа осіне айнала алмайтындығы туралы мақаланың әдіснамасында және талқылауында толық көрсетілген
Contribuições do estágio curricular supervisionado em saúde coletiva na linha de cuidados à saúde da mulher
Authors: Moneche Marques Daniel , Fortunato dos Santos Verônica , Alves Batista Guarçoni de Matos Marta , Mitre da Silva Juliana , Silveira Cardoso Lorena , Campos de Farias Franco Luís
Published: February 2025

O presente estudo é um relato de experiência descritivo reflexivo, que investigou as contribuições do estágio curricular supervisionado em saúde coletiva, no curso de graduação em enfermagem, de uma instituição privada de ensino, em Vitória – ES, na linha de atenção e cuidados à saúde da mulher. A experiência ocorreu em Unidades Básicas de Saúde, e, os estudantes participaram de atividades como visitas domiciliares, curativos, exames citopatológicos, solicitação de mamografias, pré-natal, planejamento familiar e educação em saúde. Os resultados demostraram que 419 mulheres foram alcançadas de forma direta pelas atividades desempenhadas pelos alunos no período da investigação. A vivência prática permitiu aos alunos aplicarem conhecimentos teóricos, desenvolver habilidades de comunicação e empatia, compreender a importância do trabalho em equipe e da atuação do enfermeiro na linha de cuidados à saúde da mulher, constituindo-se como essencial à formação dos futuros enfermeiros, proporcionando aprendizado integral e prático indispensável para a qualidade do cuidado em saúde coletiva.
Risk stratification of soft tissue sarcoma based on activity of prognostic molecules associated with unpolarized macrophages
Authors: Usman Muhammad , Lin Shengfa , He Guiqiong , Lu Hong
Published: February 2025

Introduction

Soft tissue sarcomas (STS), representing 80% of sarcomas, are a rare and diverse group of neoplasms with a dire prognosis. Macrophages and their subtypes play an essential role with diverse outcomes in the tumor microenvironment (TME) of cancers, including sarcomas. The aim of this study was to investigate the role of macrophages in the development and prognosis of sarcoma patients.

Material and methods

Transcriptomic data from 5 sarcoma cohorts including 581 patients and transcripts of 56,752 single cells from 6 sarcoma patients were retrieved from public databases and analyzed. The infiltration of immune cells in the TME was evaluated with the CIBERSORT algorithm. Kaplan-Meier estimation with the log-rank test and Cox regression hazards models were adopted for evaluation of prognostic impacts.

Results

Deconvolution of 22 types of immune cells via the CIBERSORT algorithm revealed macrophages as a prominent component of the TME of sarcoma patients. Of these, M0 was associated with worst prognosis. A six-gene prognostic signature, termed MRPS, was developed that was significantly positively correlated with M0 macrophages. The MRPS-stratified high-risk subgroup showed abundance of M0 macrophages, indicating inhibition of macrophage polarization, specifically the classically activated pro-inflammatory M1 phenotype. Moreover, enrichment of oncogenic pathways and glycolysis and high frequency of mutations were evident. The robustness of the MRPS as a predictive biomarker was validated in external soft-tissue sarcoma patient datasets. A nomogram based on MRPS was developed as a potentially accurate and practical predictive tool for identifying high-risk sarcoma patients with lower survival probabilities. Furthermore, the MRPS signature exhibited reliable predictive capabilities for immunotherapy response, suggesting its potential to enhance the effectiveness of personalized immunotherapy in sarcoma patients.

Conclusions

MRPS represents a robust biomarker for predicting outcomes and response to therapy in soft-tissue sarcoma patients.
Regularización de la partida 551, «Cuenta corriente con socios y administradores». Consecuencias contables y fiscales cuando los socios retiran fondos de la sociedad
Authors: Martín Zamora María Pilar , Malvárez Pascual Luis Alberto
Published: February 2025

A pesar del riesgo en los ámbitos contable y fiscal que supone el mantenimiento en el largo plazo de la cuenta de efectivo con los socios, se trata de una práctica habitual en la empresa española. Este artículo se centra en las diferentes soluciones que pueden ser utilizadas para eliminar el saldo deudor de la cuenta 551 y, por tanto, la minimización de las consecuencias contables y fiscales que se podrían producir en la sociedad y sus socios. Para ello, se lleva a cabo un doble análisis desde un doble enfoque. Concretamente, se estudian las consecuencias para la sociedad que está y continúa en funcionamiento, así como para aquella que no prosigue con la actividad y está en proceso de extinción. El estudio se completa con la doble perspectiva de socio-sociedad.
Jurisprudencia del Tribunal de Justicia de la Unión Europea en materia del IVA en 2024 y su aplicación práctica a nuestro país
Authors: Bas Soria Javier
Published: February 2025

El TJUE dicta, todos los años, un número creciente de sentencias, tanto en procedimientos prejudiciales como de incumplimiento. Siendo el IVA un impuesto armonizado en el ámbito comunitario, los criterios interpretativos del TJUE tienen gran relevancia para la comprensión y correcta aplicación del IVA.
El presente trabajo realiza un estudio detallado las sentencias dictadas en 2024, acompañándose de un juicio sobre las principales conclusiones que cabe extraer para nuestro país, tanto de orden normativo como en la aplicación de los tributos.
İki Savaş Bir Coğrafya: Yaşar Nabi Nayır’ın Balkanlar ve Türklük İle Değişen Dünyamız Adlı Eserlerınde Değişen Balkanlar İmgesi
Authors: Süzgün İlhan
Published: February 2025

1789 yılında Fransız İhtilali’nin etkisiyle ortaya çıkan milliyetçilik fikri Osmanlı Devleti gibi çok uluslu devletlerin parçalanmasına sebep olur. Söz konusu fikrin Osmanlı Devleti’ndeki en belirgin yansıması Birinci ve İkinci Balkan savaşlarıyla Osmanlı Devleti’nin Balkan coğrafyasının neredeyse tamamına yakınını kaybetmesidir. Bu iki savaşın hemen ardından patlak veren I. Dünya Savaşı, Osmanlı Devleti’nin bu savaştan yenilgiyle ayrılması ve sonrasındaki siyasi, ekonomik ve sosyal gelişmeler kaçınılmaz olarak edebî ilginin de savaş sonrası koşullara yönelmesine sebep olur. Dolayısıyla yeni sınırlarla beraber milliyetçilik fikri etrafında beliren Türk edebiyatında Balkanlar’ın ihmal edildiği görülür. Ancak Balkanlar’da yaşanan siyasi gelişmelere bağlı olarak bölgeden Türkiye’ye göçlerin başlaması, Balkan ülkeleri arasında Balkan Konferanslarının düzenlenmesi ve 1934 yılında imzalanan Balkan Antantı ile Türk edebiyatının Balkanlar’a yöneldiğini söyleyebiliriz. Gerek sanat ve edebiyat dergilerinde Balkanlar’a yönelik gezi yazıları, makaleler, şiirler ve hikâyeler gerek müstakil olarak romanlar bu yönelişin somut göstergeleridir. Bu kapsamda Üsküp doğumlu Yaşar Nabi Nayır, Balkanlar’da yaşanan gelişmeler sonrası Varlık dergisinde hem Balkanlar’ın hem Balkan Türklerinin mevcut durumlarını anlatan makaleler kaleme alır. Birçoğu Yaşar Nabi Nayır’ın Balkan seyahatindeki gözlemlerine dayanan bu makaleler daha sonra 1936 yılında Ulus Basımevi tarafından Balkanlar ve Türklük adıyla kitaplaştırılır. II. Dünya Savaşı’ndan sonra değişen yeni dünya düzeninde tekrar Balkanlar’a giden Yaşar Nabi Nayır, bu seyahatindeki gözlemlerini birçok farklı dergide yayımlar. Daha sonra bu yazıları 1973 yılında Varlık Yayınları tarafından Değişen Dünyamız ismiyle kitaplaştırılır. Söz konusu iki eser incelendiğinde yazarın Balkanlar’a yönelik düşüncelerinin değiştiği fark edilir. Bu makalenin amacı Yaşar Nabi Nayır’ın bu iki eserindeki Balkan izlenimlerinin ve düşüncelerinin neden ve nasıl farklılaştığını anlamaya
A clinician’s perspective: what tumor-organoid researchers ought to know
Authors: Lim Jeong Uk
Published: February 2025

Patient-derived tumor organoids (PDTOs) provide powerful platforms for modeling human tumors, offering insights into cancer biology and personalized therapy development. Incorporating clinical knowledge—such as cancer staging, molecular profiling, and treatment outcomes—enhances the relevance of PDTO research. Lung cancer staging systems guide tumor sample selection, thereby influencing organoid growth and treatment response studies. Clinical endpoints and molecular characteristics further align organoid experiments with real-world therapeutic challenges and patient care. Despite their potential, PDTO research faces challenges in replicating tumor heterogeneity and the tumor microenvironment, both of which are critical for studying drug resistance and treatment efficacy. Addressing these complexities requires close collaboration between researchers and clinicians to ensure that organoid models accurately reflect the clinical course of the disease. This review provides information on integrating clinical insights into PDTO research, focusing on aspects such as sample selection, clinical endpoints, and the implications of tumor staging. By bridging the gap between basic organoid research and clinical oncology, the review aims to guide researchers in enhancing the translational value of their work. A clear understanding of these clinical aspects can support the development of more robust organoid models, ultimately advancing cancer treatment strategies and improving patient outcomes.
Possibilidades de sedação química em pacientes especiais
Authors: Fujimoto Laryssa , Almeida Laura Carolina Barbosa , Galiza Thiago Costa De Oliveira , Kodama Ricardo Matsura , Araujo Ana Maria Guimarães , Teixeira Rosemary Baptista Martins , Marinho Kelly Cristine Tarquinio , Giovani Elcio Magdalena , Fonseca Alexandre luiz Affonso
Published: February 2025

The present work aims to conduct a literature review on the possibilities of chemical sedation in special patients, considering that sedation has been used as a complement for managing pain and anxiety in patients experiencing these specific feelings. The methodology adopted is based on a literature review of articles available on PubMed, Scielo, Google Scholar, books, and dental journals in Portuguese and English. In this context, a study was conducted on the techniques of chemical sedation, their indications, and contraindications specifically focused on patients with special needs. The importance of sedation management for controlling and improving the treatment of these patients is emphasized.
Metodologias Ativas no Ensino de Ciências: Concepções sobre Reprodução Humana no 8º Ano
Authors: Dos Santos Manoel Messias , De Almeida Delma Holanda
Published: February 2025

This study investigated the impact of active methodologies in the teaching of Science, specifically on the conceptions of human reproduction, in an 8th grade class. The research is of a qualitative, exploratory nature and was conducted at the Municipal School of Basic Education Oton Gaspar de Farias, located in Carneiros-AL, involving a class of 30 students. Initially, pre-tests revealed significant gaps in students’ knowledge about human reproduction, contraceptive methods, STIs, and teenage pregnancy. To address these gaps, two active methodologies were implemented: Problem-Based Learning (PBL) and Gamification. PBL involved solving real and fictional problems in groups, while Gamification used an interactive quiz about the human reproductive system. Both methodologies were developed in two 50-minute classes, promoting active and engaging learning. The post-test results showed significant improvements in students’ conceptions, with notable increases in understanding of human reproduction, contraceptive methods, and STIs. Additionally, students demonstrated greater confidence and comfort in discussing sensitive topics. The comparative analysis highlighted the effectiveness of active methodologies in promoting more meaningful and integrated learning, developing critical skills such as problem-solving, communication, empathy, and collaboration.
Prevención de suicidio: entendiendo la enfermedad como proceso
Authors: Millán-González Ricardo
Published: February 2025

El suicidio es un problema de salud pública. La prevención requiere de acciones formativas a nivel emocional, del tratamiento científico de las situaciones de riesgo suicida y de un manejo sensible por parte de los medios de comunicación. A raíz de las efemérides del día mundial de la prevención del suicidio y del día mundial de la salud mental, conviene hacer una reflexión sobre cómo la conceptualización de la enfermedad como proceso facilita el abordaje de los trastornos mentales. La comprensión de la historia de vida de cada paciente permite realizar una adecuada contextualización biográfica que explica la compleja interacción entre estrés temprano en la vida, vulnerabilidad, epigenética y circunstancias vitales, sociales y ambientales. Congruente con este trabajo clínico, la labor médica debe centrarse también en la participación en programas de educación médica continua y desde la escuela de medicina y en el diseño de acciones de promoción/prevención que consideren esta visión del continuum salud-enfermedad y que entiendan la salud física y mental como unidad. Lo anterior se fortalece con el desarrollo de las propias capacidades introspectivas para la detección del desgaste profesional como mecanismo de pérdida de la empatía.
Demonstration of Sensitive Analysis and Optical Soliton Patterns in a (4+1) Dimensional Boiti-Leon-Manna Pempinelli Equation: Dynamic Insights into Bifurcation, Chaotic Behavior
Authors: Iqbal Muhammad , Riaz Muhammad Bilal , Aziz Ur Rehman Muhammad , Martinovic Tomas , Martinovic Jan
Published: February 2025

This study aims to find exact solutions for a mathematical problem known as the (4+1)-dimensional Boiti Leon Manna Pempinelli (BLMP) equation. In order to convert the governing equation into an ordinary differential equation, we make use of an appropriate wave transformation. This transformation enables the investigation of mathematical solutions, exaggerated outcomes, and normal solutions. Furthermore, in order to accurately determine the solution to this wave, we make use of the modified Khater method. We apply the given approach to find rational, the trigonometric, and hyperbolic solutions. The selected solutions provide graphic representations that accurately depict the physical behavior of the model. Using their visualization, we are able to demonstrate how their behavior changes over time in a four-dimensional space. The use of a visual representation, which involves selecting suitable values for arbitrary components, improves the understanding of the dynamical system. Furthermore, we conduct a sensitivity analysis of the dynamical system to determine the stability of the solution. The dynamical system engages in a discussion about the existence of chaotic dynamics within the Boiti Leon Manna Pempinelli equation. It is possible to depict these chaotic phenomena using two-dimensional and three-dimensional phase portraits.
Universal Orbits: Unveiling the Connection between Chaotic Dynamics, Normal Numbers, and Neurochaos Learning
Authors: Henry Akhila , Nagaraj Nithin , Sundaravaradhan Rajan
Published: February 2025

This study explores the realm of chaotic dynamics, Neurochaos Learning (a brain-inspired machine learning paradigm) and Normal numbers, focusing on the introduction of a novel chaotic trajectory termed the Universal Orbit. The study investigates the characteristics and generation of universal orbits within two prominent chaotic maps: the Decimal Shift Map and the Gauss Map. It explores the set of points capable of forming such orbits, revealing connections with normal numbers and continued fractions. Points within the interval (0, 1) can produce universal orbits under specific conditions, highlighting the intricate relationship between machine learning, chaotic dynamics and number theory. While not all points forming universal orbits are normal numbers, the trajectory of a normal number may represent a universal orbit (under certain conditions). When employing the universal orbit for feature extraction in Neurochaos Learning, the firing time feature can be interpreted by establishing an upper bound and examining its trend. Future research aims to identify sets of points producing universal orbits under various chaotic maps, intending to enhance the performance of algorithms like the Neurochaos Learning algorithm. This study contributes to advancing our understanding of chaotic systems and their applications in artificial intelligence.
A STUDY ON ASSESSMENT OF OUTCOME OF RBSK SCREENING PROGRAMME AMONG BENEFICIARIES AGED 6 TO 18 YEARS IN THIRUVALLUR DISTRICT
Authors: Singh DL Baghath , Kumar Sathish , Jmails Rajesh , Murugan S Arun , G Pavithra , S Kirubakaran
Published: February 2025

Objectives: Rashtriya Bal Swasthya Karyakram (RBSK) is an important initiative aiming at early identifi cation and early intervention for children from birth to 18 years. The objective of this study was to estimate the number of cases( 4 Ds)detected, treated and reffered to higher centres and potential roadblocks in providing treatment and rehabilitation to referred children. Methods: This study followed a community-based cross-sectional design. The study population consisted of school-going children aged 6 to 18 years who were covered under the RBSK program in Thiruvallur district. A sample size of approximately 300 children was estimated for the study. Data collection took place over a period of two months
Managers’ idealized influence and employee commitment in Bayelsa state hospitality sector
Authors: Margaret Diete-Spiff  , Timitimi Ebisinkemefa
Published: February 2025

The research study examines Managers Idealized Influence and Employee Commitment, in the Bayelsa State hospitality sector. Research has shown a positive relationship between Transformational Leadership and Employee Commitment as it has gained attention in scholarly discuss. The rationale behind the research is to give insights on the paradigm of idealized influence as a tool for enhancing employee commitment in bayelsa state hospitality industry as little has been merely done.  The research aim was to ascertain the influence of idealized influence with dimensions of charisma, and role modelling, on affective commitment. In other to achieve this aim, a sample size of Two Hundred and Twelve (212) employees was drawn from a population of Four Hundred and Fifteen (415) employees of fifteen selected hotel firms in Yenagoa Metropolis, Bayelsa State. The primary instrument that was used to collect data was the questionnaire. Both descriptive and inferential techniques were used to analyse the collected data. The Spearman Rank Correlation Coefficient was used as the statistical method to test the hypotheses, and the SPSS program was used for analysis. The findings provide important new information on the goals of the study. From the results, it was revealed that a positively significant relationship exists between charisma, role modelling, and employee affective commitment. It was further recommended that amongst others that managers should lead by example by been enchanting for employees to see their level of influence and hence motivating them to deliver goals and also mangers should display a high sense of integrity and show a high concern for ethics as employees see them as role models at work.
Keywords: Idealized Influence, Role Modelling, Charisma, Employee Commitment, Affective Commitment.
The Impact Of Economic And Social Factors On Demand For Health Insurance: Case Study Of Metropolitan Cities
Authors: Handayani Rani , Nurmiati Nurmiati , Susanti Susanti , Puspitaloka Mahadewi Erlina
Published: February 2025

The present study reports the comprehensive study on socioeconomic aspects of health refer to social and economic factors that influence the living conditions of a person, family, or society. Health insurance is a health financing guarantee that needs to be chosen to face health risks and increasingly expensive medical costs. Socioeconomic status is related to the level of ability a person has in purchasing health services. This research aims to determine the influence of socio-economic factors on the demand for health insurance in metropolitan cities. This research uses a literature review research method which is part of qualitative research, which is related to the research subject. The results of this study show that the impact of economic and social factors or socio-economic factors can influence the demand for health insurance in metropolitan cities. The health insurance has a positive impact, there are still challenges related to the low penetration of health insurance among Indonesian people, especially in remote and rural areas. Apart from that, inadequate health insurance protection and a lack of understanding of the benefits of health insurance itself are also things that need attention. The role of the government, financial institutions and the insurance industry in increasing awareness, accessibility and reliability of health insurance products in the future will be key in strengthening the positive social and economic impact of health insurance in Indonesia.
Trends in Artificial Intelligence Research in Urology, Anesthesiology, Cardiology, and Otolaryngology: A Bibliometric Analysis (2019-2024)
Authors: Sidharta Krisna Muhammad , Alfi Reza Muhammad , Ghiffary Muamar , Satir Sayati Muhammad , Awaluddin Muhammad
Published: February 2025

Background: The application of Artificial Intelligence (AI) in medicine is rapidly evolving, particularly in urology, anesthesiology, cardiology, and otolaryngology (ENT). AI is utilized in image-based diagnosis, patient monitoring, as well as the optimization of therapy and robotic surgery. However, research trends in AI within these fields have not yet been comprehensively mapped. Methods: This study employs bibliometric analysis to evaluate publication trends in AI across these four medical fields from 2019 to 2024. Data were collected from Google Scholar, PubMed, and Scopus, then analyzed using VOSviewer and R-Bibliometrix to identify the number of publications, keyword trends, institutional collaboration networks, and the most highly cited articles. Results: The number of AI-related publications in medicine has increased from 50 articles in 2019 to 130 articles in 2024. The United States, China, and the United Kingdom have the highest number of publications. Research trends indicate that deep learning and machine learning dominate, with broad applications in disease diagnostics and medical imaging. Cluster analysis reveals four main domains: anesthesiology (120 publications), cardiology (105 publications), urology (98 publications), and ENT (80 publications). Conclusion: AI has become an essential component in the advancement of modern medicine. With the increasing number of studies and multidisciplinary collaborations, AI is projected to continue expanding in data-driven diagnosis and therapy. However, challenges in clinical validation, regulation, and AI ethics must be addressed to ensure its safe and effective use.
Spain’s Solar Gamble: Lessons in Governance from a Policy Gone Wrong
Authors: Herdem Münür Sacit
Published: February 2025

In a bright, sunlit room in Madrid, Minister of Industry and Tourism Joan Clos was reading the latest reports on Spain’s solar photovoltaic (PV) sector. Spain was witnessing a solar boom due to Royal Decree 661/2007, which offered generous feed-in tariffs (FITs) to encourage investment in solar energy. The Spanish government was aiming to become a leader in renewable energy, to reduce emissions, and to meet EU climate goals.

However, in 2008, the government of Prime Minister José Luis Rodríguez Zapatero realized that Spain’s solar PV sector had expanded far beyond expectations and was incurring unsustainable costs for the government. An industry bubble was created as investors rushed to install solar capacity. As a result, the government faced a dilemma: how to maintain Spain’s leadership in renewables without bankrupting the state. The eventual decision to cut the FITs retroactively led to a collapse of the solar PV market, financial losses, legal battles and diminished investor confidence.

This case study examines the experience of Spain’s solar PV policy from boom to bust and analyzes the gaps between the policy’s ambitious goals and its implementation. It also discusses potential steps for developing more resilient governmental frameworks for renewable energy technologies such as green hydrogen.
Consent, Pay or Settle: Meta’s Struggle for Staying Profitable in the European Union
Authors: Zard Lex
Published: February 2025

Meta’s shift from the dual option of the “consent-or-pay” model to the triple option of personalized ads, subscription with no ads, and less personalized ads, highlights the challenges of balancing consumer privacy and profitability in digital markets. The company historically relied on surveillance advertising across platforms such as Facebook and Instagram, tracking users’ behaviour to create targeted ads. This highly lucrative model helped Meta amass almost US$132 billion in advertising revenue in 2023. Meta’s consent-or-pay model embodies the conflict between data monetization and consumer privacy and autonomy, a matter being investigated by the European Commission, the outcome of which will affect the regulation of Big Tech globally.
Effect of Project Communication Practices on the Performance of the Child Protection and Education Project Implemented by World Vision International in Rutsiro District, Rwanda
Authors: Ingabire Jackline , Odengo Ruth
Published: February 2025

This study examined the impact of project communication practices on the performance of a child protection and education project implemented by World Vision International Rwanda (WVIR). Specifically, to assess the effect of participatory communication on performance of a child protection and education project, to examine the effect of results-driven communication on the performance of a child protection and education project and to assess the effect of feedback mechanism communication on the performance of a child protection and education project in Rutsiro district. The theories guided this study are participatory communication theory, feedback intervention theory and goal-oriented communication theory. The study employed the descriptive and correlational research design. The target population was 142 people including project coordination staff, project team implementers, project promoters, project beneficiaries. The population was small and accessible; therefore, the census method was used. The data was collected using questionnaire and interview guide. The data was analyzed using qualitative and quantitative approches, including descriptive statistics and inferential statistics using SPSS version 25.0. Qualitative data was collected through interviews and analyzed based on responses. The findings revealed strong positive agreement with participatory communication (M=4.27), results-driven communication (M=3.75), and feedback mechanism communication (M=4.16). Regression analysis showed that for every one-unit increase in participatory communication, project performance increased by 1.354 units (p=0.000), while results-driven communication and feedback mechanisms had negative effects on performance, with decreases of -2.081 and -0.163 units respectively (p=0.000). These findings suggest that participatory communication significantly improves project performance, while results-driven communication and feedback mechanisms do not.  Based on these findings, it is recommended that the project shares regular the project activities designed to foster trust and open communication among stakeholders and team members. Further, project should organize a regular communication training to equip project stakeholders with effective communication strategies for example how to provide feedback communication. Additionally, the project should encourage more proactive feedback through recognition programs and ensuring feedback.