bluuebunny/crossref_metadata_2025 huggingface dataset:
Leucemia linfoblástica aguda em felino: relato de caso
Authors: Oliveira Iago , Martins Oliveira Iago , Ferreira de Castro David Duarte Luísa , Eliam Pereira Luís , Donizeti Damasceno Adilson
Published: June 2020

Among the clinical forms of leukemia in small animals, chronic lymphocytic leukemia and acute lymphoblastic leukemia are mentioned. The acute form is characterized by rapid progression and low responsiveness to therapeutic modalities. It is most commonly reported in felines and clinical signs are usually associated with organs in which neoplastic infiltration occurs or hematological changes occur. Viral carriers are more predisposed. Treatment is based on the use of chemotherapy drugs, steroid anti-inflammatory drugs and supportive therapy. The importance of early diagnosis is reinforced. The objective of this work is to describe a clinical case of a young feline with acute lymphoblastic leukemia associated with feline leukemia virus infection. The final diagnosis was obtained after death through the myelogram. Even with supportive treatment, the beneficial effects were scarce and in view of the patient's clinical condition the tutor opted for eutanásia.
Insucessos e complicações no tratamento de dermatite atópica canina em poodle: relato de caso (2012-2019)
Authors: Pereira Juliana , Barth Wanis Figueiredo Katherinne , De Abreu Pereira Juliana , Wajczyk Talita , Luciana Guse Kaiser Darlene , Karoline Pereira Thaís
Published: June 2020

Canine atopic dermatitis (DAC) is an itchy inflammatory condition based on genetic predisposition to develop some hypersensitivity to food and / or environmental allergens, with clinical signs in response to exposure, characterized by severe itching. The diagnosis is made by anamnesis, by exclusion and histopathological exams. The treatment consists of controlling clinical signs, avoiding exposure to allergens as much as possible, since the condition has no cure. This case report deals with the clinical evolution of a canine poodle affected by DAC undergoing treatment over a seven-year period, concomitantly with complications due to canine pancreatitis. Clinical improvement was achieved after several attempts at treatment, the use of glucocorticoids being the only medication that significantly attenuated the clinical signs of the disease. Thus, the canine remains clinically controlled for atopic dermatitis with corticosteroids and the use of specific shampoos and moisturizers, in addition to reducing exposure to environmental allergens.
Micção inapropriada em um gato doméstico: tratamento bem sucedido com fluoxetina
Authors: Alves de Lima Moraes Bastos Priscila
Published: June 2020

Inappropriate urination in feline medicine embraces the behavior of domestic cats to urinate for no specific reason in undesirable places for their guardians. Cats with behavioral problems are two to six times more likely to be abandoned and many animals are euthanized. The aim of this paper is to report a case of inappropriate urination in a domestic cat, from which a satisfactory response was observed in pharmacological treatment with fluoxetine hydrochlorid. A male domestic breed, male, sterilized at six months of age, four years old, was taken for clinical care. The tutor's complaint focused on the elimination of urine in undesirable places, such as dog’s bed, sofa. Through history and anamnesis, it was found that the feline at the time of the consultation had a strictly domiciled habit of living and that such behavior of Inappropriate urination had started after moving to a new apartment. The owner used to live in a larger home where cats had peridomiciliated habits. Clinical examination, laboratory tests (blood count and serum biochemistry), blood glucose, feline leukemia virus (FeLV) antigen and feline immunodeficiency virus (FIV) antibody testing and feline abdominal ultrasound did not result in changes. Noteworthy. Thus, through the diagnosis of elimination related to primary environmental / social factors, environmental enrichment measures were adopted that did not result in a satisfactory response. Consequently, the pharmacological therapy was prescribed with fluoxetine hydrochloride at a dose of 0.5 mg / kg orally every 24 hours until further recommendations. The animal presented improvement during the first 10 days after the start of drug treatment and 12 months after it remained without signs of periuria. There was no side effect associated with the therapy adopted. The factors that trigger the inappropriate elimination disorder are not necessarily those that maintain them, therefore justifying the non-response only to the environmental management adopted. Such a report may contribute to a better understanding and adoption of treatment techniques for inadvertent urination disorder in cats, which may help to reduce the tutor's dissatisfaction with felines that exhibit such behavior and consequently reduce the number of animals abandoned and euthanized because of this disorder.
Estudos científicos sobre gatos ferais no Brasil
Authors: Pereira Gabriel Jorge , Santos Prezoto Helba Helena , Neves Dias Anna Marcella , Oshio Leonardo Toshio
Published: June 2020

Cats have been living with humans for a long time and this relationship has been getting closer and closer, however many behavioral problems are the result of failures in assessing a cat's real needs and environmental conditions. These problems are the main cause of abandonment, taking animals from the streets to euthanasia. In urban environments, the presence of feral animals has become a major public health concern because of feral cats, only a small portion is vaccinated or has a responsible guardian. The present study aimed to analyze scientific publications and profile the studies done in Brazil on the theme of “feral cats”. Data were collected from surveys of scientific studies (articles, books, monographs, dissertations and theses) made digitally available on search and research sites, being Google Academic, Scielo, PubVet, PubMed. We found 58 published scientific studies, from 2002 to 2019, of which 28 are related to diseases and zoonoses, 20 related to predation and environmental impact and 10 to animal behavior. Publications on the topic began in 2002, peaking in 2015, and the southeastern region of the country was where the largest number of studies is concentrated. It is concluded that studies on the subject are lacking, requiring further research to evaluate the behavior of feral cats.
Alopecia X em cães: revisão
Authors: De Carvalho Lima Gondim Adriana , Leite Araujo Adjanna Karla
Published: June 2020

Alopecia in dogs is a frequent finding at veterinary dermatological consultations, may be caused by various skin diseases and even systemic. Alopecia X is a dermatopathy that occurs most often in Nordic breeds, especially in German Spitz dogs, about which there is not much scientific knowledge today. Its pathogenesis has not been well understood and is currently believed to be caused by an inherited component associated with changes in sensitivity to hair follicle hormone receptors. The most used treatment is the castration of these animals, associating the administration of some drugs in certain cases and the diagnosis is made by observing the patient's response to the treatment instituted. Being a disease about which there is not much published literature, this article aims to gather important information about this dermatopathy.
Pengukuran, Assessment dan Evaluasi dalam Pembelajaran Matematika
Authors: Zainal Nur Fitriani
Published: June 2020

Evaluasi merupakan salah satu komponen penting dan tahap yang harus ditempuh oleh guru untuk mengetahui keefektifan pembelajaran. Hasil yang diperoleh dari evaluasi dapat dijadikan pertimbangan bagi guru dalam memperbaiki dan menyempurnakan program dan kegiatan pembelajaran. Istilah-istilah yang digunakan dalam sistem evaluasi, yaitu pengukuran,  penilaian, dan evaluasi. Penelitian ini merupakan library research yang mengkaji referensi tentang  pengukuran, assessment, dan evaluasi dalam pembelajaran matematika. Dalam kegiatan pembelajaran, evaluasi didahului oleh penilaian (assessment), sedangkan penilaian didahului oleh pengukuran. Dalam pengukuran, dilakukan kegiatan membandingkan hasil pengamatan dengan kriteria. Kemudian, hasil pengukuran ditafsirkan dan dideskripsikan dalam proses penilaian. Selanjutnya, evaluasi, yaitu menetapkan nilai atau implikasi perilaku. Jenis instrumen yang digunakan pada penilaian adalah tes dan non-tes. Langkah dalam menganalisis hasil non-tes, yaitu: a) mentransfer data kualitatif hasil angket menjadi data kuantitatif dan b) membandingkan total skor (rerata skor) tiap siswa dengan total skor netral (rerata skor netral). Di sisi lain, langkah yang digunakan untuk menganalisis hasil tes, yaitu: a) menskor dan b) penafsiran skor tes.
Hegemonik İdeoloji, Birey ve Psiko-Politik Etkileşimler: Persepolis Filmi Örnekliği
Authors: ŞİMŞEK B. Şüheda , GEÇER Ekmel
Published: June 2020

Louis Althusser ideolojiyi siyasal ve toplumsal rolleri bulunan bir tasarım olarak değerlendirmiş; temel fonksiyonunu ise, toplumsal yapının ve üretim ilişkilerinin devam ettirilmesi olarak görmüştür. Birey; farkında olmadan ya da milliyet, tarihsel öğrenim, sosyo-politik ortam ve sonrasında oluşan psikolojik yaklaşımlar gibi nedenlerle doğruluğuna inanarak, ideolojik etkiye maruz kalmaktadır. Bu yönlendirme sürecinde birey, yine Althusser’in ifadesiyle, devletin ideolojik aygıtları olan eğitim, din, siyaset, kültür, aile, haberleşme ve sanat gibi unsurlardan etkilenir ya da mevcut bakış açısını güçlendirmek için onlardan faydalanır.Bu bağlamda elinizdeki makale; Althusser’in ideoloji kavramını, devletin ideolojik aygıtları çerçevesinde açıklamayı ve çağrılma aracılığıyla özneleştirilmiş bireyin ideolojiyle çevrelenmiş hayatında, söz hakkı olup olmadığını tartışmayı amaçlamaktadır. Diğer bir ifadeyle çalışma; zamanla ideolojilerin mücadele alanı olan hegemonik süreçlerin bireyler üzerindeki etkilerini anlama çabasının ürünüdür. Bu amaçla; bir animasyon filmi olan Persepolis örnekliğinde, Althusser’in devletin ideolojik aygıtları kuramının ne şekilde ve hangi kalıplarla yansıtıldığı ortaya çıkarılmaya çalışılmıştır. Filmin analizi doküman incelemesi yoluyla yapılmış, yöntem olarak önceden belirlenmiş ölçütleri karşılayan olguların çalışıldığı ölçüt örnekleme metodu benimsenmiştir. Yapılan değerlendirmede; devletin, ideolojik aygıtlar aracılığıyla birey üzerinde hegemonya kurmaya çalıştığı, bireyin ise ancak Gramsci’nin alternatif hegemonya alanlarını kullanarak ve Hall’un bahsini ettiği okuma süreçlerini geliştirmesiyle bu durumdan kurtulabileceği, ancak bunun gerçekleşmesinin hegemonyanın derecesine bağlı olarak yoğun işletildiği dönemlerde çok zor olduğu anlaşılmıştır. Bununla birlikte, hegemonyanın güçlü ideolojik etkisine rağmen, egemen doktrinlerden farklı bir yaklaşıma sahibi olmanın, her koşulda mümkün olduğu sonucuna varılmıştır.
Reinforcing Risk Perception to Induce Exercise Intention: Role of Systematic Interaction from Social Marketing Perspectives
Authors: Ahmad Farooq , Qaisar Muhammad Nawaz , Hamid Syed Ali Raza
Published: June 2020

The study examined the relationship between systematic interaction, fear appeals, and exercise intention using group-centered and participatory approaches. The longitudinal experimental design was used to understand the phenomenon of fear appeals (risk perception) for adopting sustained physical activities. The sample comprised two treatment conditions i.e. experimental group and control group to measure the impact of interventions for verification of the proposed conceptual model. The findings indicate that risk perception mediated the relationship between systematic interaction and exercise intention. Moreover, systematic interaction has a positive effect on risk perception and exercise intention. The findings conceptually advance the fear appeal theory with a new lens using a participatory paradigm to augment sustained behavior change. We advocate that use of systematic interaction adds value in expanding the scope of a theoretical base for marketing.
A comparison of the perioperative outcomes of anterior surgical techniques for the treatment of multilevel degenerative cervical myelopathy
Authors: Badhiwala Jetan H. , Leung Sean N. , Ellenbogen Yosef , Akbar Muhammad A. , Martin Allan R. , Jiang Fan , Wilson Jamie R. F. , Nassiri Farshad , Witiw Christopher D. , Wilson Jefferson R. , Fehlings Michael G.
Published: June 2020

OBJECTIVE

Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord dysfunction in adults. Multilevel ventral compressive pathology is routinely managed through anterior decompression and reconstruction, but there remains uncertainty regarding the relative safety and efficacy of multiple discectomies, multiple corpectomies, or hybrid corpectomy-discectomy. To that end, using a large national administrative healthcare data set, the authors sought to compare the perioperative outcomes of anterior cervical discectomy and fusion (ACDF), anterior cervical corpectomy and fusion (ACCF), and hybrid corpectomy-discectomy for multilevel DCM.

METHODS

Patients with a primary diagnosis of DCM who underwent an elective anterior cervical decompression and reconstruction operation over 3 cervical spinal segments were identified from the 2012–2017 National Surgical Quality Improvement Program database. Patients were separated into those undergoing 3-level discectomy, 2-level corpectomy, or a hybrid procedure (single-level corpectomy plus additional single-level discectomy). Outcomes included 30-day mortality, major complication, reoperation, and readmission, as well as operative duration, length of stay (LOS), and routine discharge home. Outcomes were compared between treatment groups by multivariable regression, adjusting for age and comorbidities (modified Frailty Index). Effect sizes were reported by adjusted odds ratio (aOR) or mean difference (aMD) and associated 95% confidence interval.

RESULTS

The study cohort consisted of 1298 patients; of these, 713 underwent 3-level ACDF, 314 2-level ACCF, and 271 hybrid corpectomy-discectomy. There was no difference in 30-day mortality, reoperation, or readmission among the 3 procedures. However, on both univariate and adjusted analyses, compared to 3-level ACDF, 2-level ACCF was associated with significantly greater risk of major complication (aOR 2.82, p = 0.005), longer hospital LOS (aMD 0.8 days, p = 0.002), and less frequent discharge home (aOR 0.59, p = 0.046). In contrast, hybrid corpectomy-discectomy had comparable outcomes to 3-level ACDF but was associated with significantly shorter operative duration (aMD −16.9 minutes, p = 0.002).

CONCLUSIONS

The authors found multiple discectomies and hybrid corpectomy-discectomy to have a comparable safety profile in treating multilevel DCM. In contrast, multiple corpectomies were associated with a higher complication rate, longer hospital LOS, and lower likelihood of being discharged directly home from the hospital, and may therefore be a higher-risk operation.
Unilateral pallidotomy as a potential rescue therapy for cervical dystonia after unsatisfactory selective peripheral denervation
Authors: Lai Yijie , Huang Peng , Zhang Chencheng , Hu Liangyun , ME  , Deng Zhengdao , Li Dianyou , Sun Bomin , Liu Wei , Zhan Shikun
Published: June 2020

OBJECTIVE

Selective peripheral denervation (SPD) is a widely accepted surgery for medically refractory cervical dystonia (CD), but when SPD has failed, the available approaches are limited. The authors investigated the results from a cohort of CD patients treated with unilateral pallidotomy after unsatisfactory SPD.

METHODS

The authors retrospectively analyzed patients with primary CD who underwent unilateral pallidotomy after SPD between April 2007 and August 2019. The Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) was used to evaluate symptom severity before surgery, 7 days postsurgery, 3 months postsurgery, and at the last follow-up. TWSTRS subscores for disability and pain and the 24-item Craniocervical Dystonia Questionnaire (CDQ-24) were used to assess quality of life.

RESULTS

At a mean final follow-up of 5 years, TWSTRS severity subscores and total scores were significantly improved (n = 12, mean improvement 57.3% and 62.3%, respectively, p = 0.0022 and p = 0.0022), and 8 of 12 patients (66.7%) were characterized as responders (improvement ≥ 25%). Patients with rotation symptoms before pallidotomy showed greater improvement in TWSTRS severity subscores than those who did not (p = 0.049). The most common adverse event was mild upper-limb weakness (n = 3). Patients’ quality of life was also improved.

CONCLUSIONS

Unilateral pallidotomy seems to offer an effective and safe option for patients with CD who have otherwise experienced limited benefits from SPD.
Reliability and quality of online patient education videos for lateral lumbar interbody fusion
Authors: White Michael D. , Latour Kristy , Giordano Martina , Taylor Tavis , Agarwal Nitin
Published: June 2020

OBJECTIVE

There is an increasing trend among patients and their families to seek medical knowledge on the internet. Patients undergoing surgical interventions, including lateral lumbar interbody fusion (LLIF), often rely on online videos as a first source of knowledge to familiarize themselves with the procedure. In this study the authors sought to investigate the reliability and quality of LLIF-related online videos.

METHODS

In December 2018, the authors searched the YouTube platform using 3 search terms: lateral lumbar interbody fusion, LLIF surgery, and LLIF. The relevance-based ranking search option was used, and results from the first 3 pages were investigated. Only videos from universities, hospitals, and academic associations were included for final evaluation. By means of the DISCERN instrument, a validated measure of reliability and quality for online patient education resources, 3 authors of the present study independently evaluated the quality of information.

RESULTS

In total, 296 videos were identified by using the 3 search terms. Ten videos met inclusion criteria and were further evaluated. The average (± SD) DISCERN video quality assessment score for these 10 videos was 3.42 ± 0.16. Two videos (20%) had an average score above 4, corresponding to a high-quality source of information. Of the remaining 8 videos, 6 (60%) scored moderately, in the range of 3–4, indicating that the publication is reliable but important information is missing. The final 2 videos (20%) had a low average score (2 or below), indicating that they are unlikely to be of any benefit and should not be used. Videos with intraoperative clips were significantly more popular, as indicated by the numbers of likes and views (p = 0.01). There was no correlation between video popularity and DISCERN score (p = 0.104). In August 2019, the total number of views for the 10 videos in the final analysis was 537,785.

CONCLUSIONS

The findings of this study demonstrate that patients who seek to access information about LLIF by using the YouTube platform will be presented with an overall moderate quality of educational content on this procedure. Moreover, compared with videos that provide patient information on treatments used in other medical fields, videos providing information on LLIF surgery are still exiguous. In view of the increasing trend to seek medical knowledge on the YouTube platform, and in order to support and optimize patient education on LLIF surgery, the authors encourage academic neurosurgery institutions in the United States and worldwide to implement the release of reliable video educational content.
Tools for assessing the financial stability of the enterprise
Authors: Boltava A. L. , Budtueva V. A. , Romanova V. A.
Published: June 2020

This article describes in detail one of the main tools for assessing the financial stability of an enterprise. The study describes a method for analyzing the financial stability of an enterprise based on relative indicators: its own working capital, the aggregate of its own and long-term funds, the total amount of sources for the formation of reserves and costs of an economic entity, and shows practical calculations on the example of an economic entity. The study reveals the essence of the method for determining one of the four types of financial situation: absolute stability, normal stability, unstable and crisis financial condition. The types are characterized based on the values of the threecomponent indicator of financial stability. Based on the results of the analysis of financial stability based on relative indicators, conclusions and proposals are made, with emphasis on the stabilization of the financial situation. The advantages and disadvantages of using the studied tool for assessing the financial stability of the enterprise are also highlighted.
Analysis of the pandemic impact on aviatransportation and tourism in Russia
Authors: Polzikova E. V. , Yurchenko A. A.
Published: June 2020

The article examines the impact of the pandemic on both the air transport sector and the tourism sector in General in Russia. The problems faced by the tourism sector in General, and the air transport sector in particular, are identified, and possible solutions to these problems are presented.
The improvement of blood smears coloring for the determining of fish cytometric blood parameters
Authors: Kurchenko V , Sharamok T , Marenkov O
Published: June 2020

Fish erythrocytes are sensitive to environmental pollution and their morphological changes can be used as a bioindicator of the toxicity of the aquatic environment. The disadvantage of existing methods of blood smears coloring is that they are inconvenient in the field conditions, when it is necessary to examine the fish blood during ichthyological researches or they are long-lasting. In this regard, there is a need for a fast and reliable method of coloring blood cells of fish, which can be used both in laboratory and in field conditions. The aim of the work was to improve the method of coloring fish blood smears for easier and faster execution, without degradation of the quality of colouring. The subject of the research was the young Cyprinidae fish. The improved method is based on the classic method of painting by Papenheim, but differs in the interval of time devoted to colouring in a solution of the dye Romanovskogo. The analysis showed that erythrocytes on medicine that were in the Romanovsky solution for 5 minutes had the correct form with clear contours, a dark purple core located in the center of the cell. It has been found that this method can be used in cytometric researches to determine such indicators: large longitudinal and small transverse diameters of erythrocytes, erythrocyte area, erythrocyte core area, nuclear-cytoplasmic ratio, percentage of mature and immature erythrocytes and their forms. It can also be used in analyzing the presence of erythrocyte pathologies. It has been established that reduction of time (from 20 minutes to 5 minutes) of preparations in the dye solution of Romanovsky does not affect the quality of their coloring, and therefore it is a reliable and fast way that can be successfully applied in morphological and cytometric studies of blood of fish.
Fish in water bodies of the Emerald Network of Ukraine
Authors: Demchenko Viktor , Demchenko Nataliia
Published: June 2020

The paper provides information on the structure of sites of the Emerald Network of Ukraine as special areas of conservation, focused at ensuring the protection of natural fauna, flora and habitats. The development of this network was initiated for the implementation of a set of resolutions of the Berne Convention (1979), and principles of its formation are basically similar to Natura 2000. As of 2019, a total of 271 Emerald sites were designated in Ukraine. According to studies, the water bodies of the network are inhabited by 25 fish species. The data were extracted from up-to-date ichthyological publications on the distribution of fish species in Ukrainian water bodies, catalogues of collections of various zoological museums, regional faunal cadastres, and own research. Analysis of the fish species composition in the sites has shown that the most common and found in more than 60% of the sites are Cobitis taenia, Rhodeus sericeus amarus, Misgurnus fossilis. This can be explained by characteristics of their biology and tolerance to environmental conditions. Endemic species are extremely rare in the Emerald sites and narrowly localized in several river basins. In particular, they are Zingel zingel, Umbra krameri, Eudontomyzon danfordi, Hucho hucho, and Leuciscus souffia recorded in 5-6 sites of the network. Further research is required that will be focused at the development of an integral network of Emerald sites in Ukraine. For this purpose, ichthyological reserves of general and local significance may be considered as promising areas. The analysis of the species number and distribution in water bodies of Ukraine is quite relative and requires additional special field studies. In addition, a qualitative assessment of the number of fish species in promising areas requires ichthyological research methods to be unified and an effective monitoring system be introduced.
Distribution of Muscari botryoides (Asparagaceae) in Ukraine
Authors: Boychuk Svitlana
Published: June 2020

The article contains generalized information about distribution of Muscari botryoides (L.) Mill. in Ukraine. It listed in the third edition of the Red Data Book of Ukraine with the conservation status "disappearing". It is protected in the «Mocharka» and «Shyiania» nature reserves. The Red Data Book of Ukraine contains information that the studied species grows only in the Zakarpattia region. A small number of publications dated after 1960 concerning to M. botryoides attest about the necessity of studying this species in order to obtain information about its current distribution in Ukraine. The work purpose was to generalize the literature and herbarium data about M. botryoides distribution in Ukraine. After processing literature data and herbarium materials (LWS, CHER, UU) a list of localities and a distribution map of M. botryoides in Ukraine have been compiled. It is established that the species exist not only in the Zakarpattia region, but also grows in the Ivano-Frankivsk, Chernivtsi and Ternopil regions. M. botryoides grows in light xerothermic oakerys, outskirts, secondary forest cenosis on rich warm brown soils, formed on deluvium of igneous rocks, in Querco-Fagetea and Quercetea pubescentis communities, occasionally in the communities with Robinia pseudoacacia. Species also grows in meadow steppes, steppe and after-forest meadows, on karsts outcrops. It prefers xeremosephytic environmental conditions. In general, 15 localities of the species have been found in Ukraine. Over the past 20 years only 3 sites have been documentally confirmed: in Bushtyno Urban-type settlement (Tiachiv district of Zakarpattia region), Kholmovets village (Vynohradiv district of Zakarpattia region) and between Drachyntsi and Kostyntsi villages Chernivtsi regions. Also 5 new localities have been found: in Probabyn village (Horodenka District, Ivano-Frankivsk Region), in Vyshnivka and Krasnostavtsi villages (Sniatyn District, Ivano-Frankivsk Region), in Onok village (Vynohradiv District, Zakarpattia Region) and in the NNP "Synevyr" (Mizhhirsky and Khust districts of Zakarpattia region).
Lipid profile of blood serum in mice under conditions of bisphenol a administration and vitamin a different suplementation
Authors: Borschovetska Vira , Marchenko Mykhailo
Published: June 2020

The purpose of the study was to determine the lipid profile of blood serum and glucose tolerance in mice under conditions of bisphenol A (BPA) administration and different vitamin A consumption. The experimental animals were wild type mice with normal retinoids supplementation and transgenic mice (Lrat-/-) that are unable to esterify of retinol and do not have retinoid stores in liver. BPA, dissolved in corn oil (used as a vehicle), was administered per os daily for 3 days at a dose of 50 mg/kg body weight. Vitamin A overconsumption was modeled by administration of retinyl acetate in a very high dose of 3000 IU at 12 h intervals for 3 days. In the present study dyslipidemia was observed in the mice received 50 mg/kg BPA represented by significant higher triglycerides (at 1,4-fold), total cholesterol (at 2,2-fold), LDL-C, VLDL-C and HDL-C (46%, 39% and 2,8-fold respectively) than those mice of control group received vehicle. Administration of BPA also resulted in disruptions of glucose homeostasis, consisting of hyperglycemia (11±1.11 mmol/l) and glucose intolerance of animals. These BPA’s actions were attributed to its ability of binding to nonclassical membrane estrogen receptor as well as the G-protein coupled-receptor 30 (GPR30) and to act through nongenomic pathways. In knockout mice that did not have retinoid stores in the liver, indicators of both lipid profiles and glucose homeostasis were not significantly different from identical indicators of vehicle-treated mice. Additional 3000 IU retinyl acetate expose simultaneously with administration of 50 mg/kg BPA enhanced the lipogenic effect of xenobiotics in the wild type animals and induce its obesonic adverse effect in Lrat-/- mice. Thus, BPA exposure results in metabolic disorders consisting of hyperglycemia, glucose intolerance, hypercholesterolemia and hyperlipidemia. Retinoids enhanced the BPA action as an obesogen.
The content of methemoglobin and carboxygemoglobin in rats red blood cell under the toxic damage after alimentary protein deprivation
Authors: Kopylchuk Halyna , Nykolaichuk Ivanna , Kliuchnyk Yaroslav
Published: June 2020

The study of the content of total hemoglobin and its pathological derivates methemoglobin and carboxyhemoglobin in rats’ red blood cell under the toxic damage and alimentary protein deprivation are presented. In order to simulate the low-protein diet of animals for 28 days were kept, an isoenergy diet containing 4.7% protein, 10% fats and 85.3% carbohydrates, which was calculated according to the American Institute of Nutrition recommendations. The simulation of acute toxic damage was performed by per os acetaminophen-administration to experimental animals at doses of 1250 mg/kg of animal body weight. It was found that in experimental animals the 2-fold decrease in erythrocytes counts compared with the values of the control group was observed under the toxic damage after alimentary protein deprivation. In this case, both protein deficiency and the administration of acetaminophen toxic doses have a clear effect on the studied indicator. At the same time, a decrease of erythrocyte counts is accompanied by a simultaneous decrease of total hemoglobin content in rat erythrocyte hemolysate. In animals consuming a low protein diet, this may be due to a deficiency of essential amino acids involved in the synthesis of globin’s polypeptide chains. The maximal increase of methemoglobin content (5-fold compared with control) in rats’ erythrocyte hemolysate was recorded under the administration of acetaminophen toxic doses after alimentary protein deprivation. In these experimental conditions this may be associated with a decrease of methemoglobin reductase activity, which causes methemoglobin accumulates in erythrocytes in the form of Heinz bodies. An increase of the carboxyhemoglobin level in rats’ erythrocyte hemolysate of all the experimental groups compared with the control under the conditions of toxin administration after protein deficiency, probably indicates impaired synthesis and/or degradation of heme-containing proteins.
The content of sialic acids in blood plasma of rats under the conditions of acetaminophen-induced hepatotoxicity after alimentary protein deprivation
Authors: Kopylchuk Halyna , Nykolaichuk Ivanna , Hanusiak Maria
Published: June 2020

The work is devoted to the study of the fractional distribution of sialic acids in the blood plasma of rats under the conditions of toxic damage with acetaminophen after alimentary protein deprivation. The content of free, protein-bound and oligo-bound sialic acids in the blood plasma of animals was investigated under experimental conditions. The animals consumed a semi-synthetic diet during the experiment according to the recommendations of the American Institute of Nutrition. In order to simulate alimentary protein deprivation, rats received a low-protein diet containing 1/3 of the standard daily protein requirement daily for 28 days. The animals were modeled acute toxic damage with acetaminophen after four weeks of experimental diet. The administration of the toxin was carried out at doses of 1250 mg/kg animal body weight in suspension in 2 % starch gel solution once a day for 2 days by gavage. The concentration of free, protein- and oligo-bound sialic acids was determined spectrophotometrically at 549 nm by color reaction with thiobarbituric acid. Removal of non-sialic acid specific chromogens were performed by the addition of n-butanol. It has been shown that the increase of total sialic acids in the blood plasma of protein-deficient rats (by 40% compared to control) is due only to the increase in the level of the oligo-bound fraction. Thus, protein deficiency is a key factor in the established changes, which probably indicates the intensification of catabolism processes of intracellular easily mobilized proteins under the conditions of protein deficiency in the diet. At the same time, toxin (acetaminophen) intake, leads to an increase in the concentration of total sialic acids, mainly due to the increase of free and protein-bound fractions, which indicates the development of inflammatory processes in the tissues of the body, regardless of the amount of exogenous protein consumed.
Analysis of sorbing method of water treatment from oil
Authors: Glibovytska Nataliia , Plaksiy Lesia
Published: June 2020

The efficiency of simple and accessible methods of cleaning of oil-contaminated water is investigated. The maximum absorption capacity of cotton as a natural material is identified, that quickly absorbs oil components and does not require the use of additional resources to combat water contamination. It is found that natural charcoal absorbent is inefficient in comparison with other methods of water purification from oil and requires a long time and additional pollution catchers, which is economically unprofitable. Synthetic polymer foam and white coal absorb oil in a short time, but in the latter case, nevertheless, small spots remain on the surface of the water. According to the efficiency of oil absorption by natural and synthetic materials, we can distinguish the following series of investigated materials: black coal → foam → white coal → cotton.
A new location of Spiranthes spiralis (L.) Chevall. (Orchidaceae Juss.) on Transcarpathian Lowland
Authors: Furyk T
Published: June 2020

Information about new records of Spiranthes spiralis (L.) Chevall. (Orchidaceae Juss.), European-Mediterraneum origin species, on the Transcarpathian Lowland is presented. The population represented by seven flowering individuals planthave been idenfied in degraded hayfields plant communities in Henderovytsia village of Mukachevo district of Transcarpathian Region.
Nueva propuesta de evaluación de la Reputación Corporativa: Indicador de Desempeño Reputacional
Authors: Ferruz González Sonia Aránzazu
Published: June 2020

Partiendo del concepto de reputación de consenso propuesto por la autora en anteriores investigaciones, se realiza un análisis comparativo de las metodologías existentes más reconocidas para evaluar la reputación corporativa, tanto desde el ámbito académico como profesional (monitores de reputación), y se identifican los diferentes planteamientos teóricos, sus componentes y los conceptos de reputación subyacentes a las metodologías. Comparados todos los métodos, se procede a su clasificación y a su análisis crítico. El trabajo de investigación concluye con la propuesta de una metodología de evaluación de la reputación corporativa a través de indicadores de rendimiento que se ajusta al concepto de reputación de consenso, y que aspira a ser una metodología válida y aceptada para la evaluación de la reputación.
The Anxiety Level of Mother Presectio Caesar with Benson’s Relaxation Therapy
Authors: Pardede Jek Amidos , Tarigan Irvandy
Published: June 2020

Background: Sectio caesar is a surgical action to remove a baby from the uterus by an incision in the mother's abdominal wall that aims to save the mother and baby so that the mother can deliver the baby in a healthy condition and can be born safely. Sectio Caesar often makes the mother experience anxiety that affects physical conditions that can interfere with the process of the cesarean section, so it requires the treatment of Benson in dealing with anxiety.Purpose: Analyse differences between before and after Benson’s relaxation therapy on pre-sectional Cesarean anxiety level.Methods: The study used the Quasy experiment One Group pre and Post-test design to. The technique of taking samples using purposive sampling and the number of samples wee 14 respondents. Data collection used a questionnaire. Data analising used McNemar test with a significance of 95% and p 0.05.Results: The anxiety level of pre-cesarean section mothers before was 78.6% and after Benson therapy was 85.7% with a p-value 0.004 ( 0.05).Conclusion: The Benson’s relaxation therapy is working on pre-section cesarean mothers by decreassing mothers’ anxiety levels.
Performance analysis of radial flux and axial flux permanent magnet generators for low- speed wind turbine applications
Authors: Sitheswaran Bhuvaneswari , Pandarinathan Sivaraman , Alagu Matheswaran , Ponnusamy Prem
Published: June 2020

India has enormous wind potential and average wind velocity is about 6 m/s, whereas the conventional wind turbine mechanism is operated at 7 m/s–12.5 m/s. It is necessary to design low speed wind energy conversion to harvest the electrical energy from wind. Mostly, Radial flux permanent magnet generator (RFPMG) is used for low speed wind turbine applications. This Conventional RFPMG has the drawbacks of low flux density and increase in weight due to large number of poles accommodation. In order to overcome the above setbacks, this paper proposes a double sided coreless axial flux permanent magnet generator (AFPMG) for low speed wind energy conversion applications. The performance analysis of the proposed AFPMG is carried out through finite element method using ANSYS Maxwell software. Finally the performance of RFPMG and AFPMG is compared based on the flux linkage, flux density, induced emf, stator current, moving torque, cogging torque, Total Harmonic Distortion (THD), material consumption, losses and efficiency. It is evident from the results that AFPMG gives the better performance than RFPMG in all such aspects.
Optimal defense strategy model based on differential game in edge computing
Authors: Sun Yan , Li Yaobing , Chen Xuehong , Li Jun
Published: June 2020

Edge computing extends the cloud computing paradigm to the edge of the network to offset the shortcomings of traditional cloud computing in mobile support, low delay, and location awareness. However, traditional complicated encryption algorithms, access control measures, identification protocols, and privacy protection methods are inapplicable to security defense of edge computing given the multisource data fusion characteristics of edge computing, superposition of mobile and the Internet, and resource limitations in storage, computing, and battery capacity of edge terminals. Therefore, a reasonable defense model for complicated dynamic edge computing environment must be established. In accordance with the characteristics of limited resources of edge devices, combined with dynamic game theory, this study proposes an optimal defense strategy model based on a differential game and solves the optimal defense strategy of edge nodes in infinite and finite-horizons. The optimal defense strategy of the edge nodes was simulated under different conditions, and the simulation verifies that the edge nodes can obtain the optimal defense effect with minimum resource consumption when cooperating to form the defense system.
Influence model of wind power capacity in load response system under smart grid environment
Authors: Liu Yan , Gu Ya-li , Wang Jing-min
Published: June 2020

With the increasing global energy crisis, wind power is gradually favored by people for its sustainability and cleanliness. When the wind power is connected with the power system, the problem of grid connection must be overcome. In order to better meet the demand load interactive response in smart grid environment, a multi-layer scheduling two-dimensional operation model was proposed. The mechanism of wind power uncertainty was analyzed. Thus, wind power prediction algorithm was established, and the concept of probability based multi-level scheduling was introduced to improve the adaptability of the model as a whole. In order to verify the reliability and effectiveness of the method, case experiments were carried out. The results show that the method can effectively help wind power consumption when ensuring economic and reliable conditions.
Uncertainty prediction method for traffic flow based on K-nearest neighbor algorithm
Authors: Yang Lingmin
Published: June 2020

In order to overcome the problem of low fitting between traffic uncertainty prediction results and actual values in existing research methods, a traffic flow uncertainty prediction method based on K-nearest neighbor algorithm is proposed. The original database, classification center database, k-nearest neighbor database and intermediate search database are used to construct the database needed in the prediction process. Based on the database, multivariate linear regression is used to assign weights to state variables, and k-nearest neighbor algorithm and Kalman filter are used to update the weights to adapt to the uncertainties of traffic flow until the predicted values are obtained, and the uncertainties of traffic flow are predicted. The experimental results show that the maximum average absolute error and average relative error of the proposed method are 0.018 and 0.02, respectively. Compared with the traditional method, the proposed method has higher overall prediction accuracy, higher fitting degree, and is feasible.
Short-term forecasting method for dynamic traffic flow based on stochastic forest algorithm
Authors: Wumaier Heniguli , Gao Jian , Zhou Jin
Published: June 2020

In order to overcome the problems of low accuracy and long time-consuming in traditional short-term forecasting methods for dynamic traffic flow, a short-term forecasting method for dynamic traffic flow based on stochastic forest algorithm is proposed in this paper. This method chooses short-term forecasting equipment for dynamic traffic flow, eliminates invalid data from the collected data, and normalizes the available data to complete data preprocessing before traffic flow forecasting. A combined forecasting model is established to optimize the output of the pretreatment results and complete the dynamic traffic flow rate forecasting. On this basis, the stochastic forest algorithm is introduced to train the sampling set of flow rate decision tree and generate short-term flow decision tree to realize short-term forecasting of dynamic traffic flow. The experimental results show that the forecasting time of the proposed method is short, always less than 0.5 s, and the forecasting accuracy is high, with more than 97%, so it is feasible.
A predictive context aware collaborative offloading framework for compute-intensive applications
Authors: Shalini Lakshmi A.J. , Vijayalakshmi M.
Published: June 2020

The resourceful mobile devices with augmented capabilities around human pave the way for utilizing it as delegators for resource-constrained devices to run compute-intensive applications. Such collaborative resource sharing policy among mobile devices throws challenges like identifying competent alternatives for offloading and diminishing time consumption of pre-offload process to accomplish remarkable offloading. This paper presents a Mobile Cloud Computing framework with Predictive Context-Aware Collaborative Offloading Process (PCA-COP) that fixes these challenges through conductive alternative discovery. This context-aware discovery adapts a multi-criteria decision making model of Analytic Hierarchy Process (AHP) accompanied with Fuzzy categorization to rank the alternatives and classify them into Highly, Fairly, Less offload-suitable devices. Moreover, to make alternative selection optimal, a Dataset Curtailment enabled Artificial Neural Network (DCANN) prediction is incorporated on AHP-Fuzzy model, which truncates training dataset using Conditioned Stratified Sampling (CSS). The prototype framework is evaluated with mobile applications in the classroom under dynamic context environments.
Multi-task learning model for aspect term extraction and aspect polarity classification based on dual-labels
Authors: Zeng Biqing , Zeng Feng , Yang Heng , Zhou Wu , Xu Ruyang
Published: June 2020

Aspect-based sentiment analysis (ABSA) is a hot and significant task of natural language processing, which is composed of two subtasks, the aspect term extraction (ATE) and aspect polarity classification (APC). Previous researches generally studied two subtasks independently and designed neural network models for ATE and APC respectively. However, it integrates various manual features into the model, which will consume plenty of computing resources and labor. Moreover, the quality of the ATE results will affect the performance of APC. This paper proposes a multi-task learning model based on dual auxiliary labels for ATE and APC. In this paper, general IOB labels, and sentimental IOB labels are equipped to efficiently solve both ATE and APC tasks without manual features adopted. Experiments are conducted on two general ABSA benchmark datasets of SemEval-2014. The experimental results reveal that the proposed model is of great performance and efficient for both ATE and APC tasks compared to the main baseline models.
Power flow management scheme of hybrid renewable energy source to maximize power transfer capability using I2HOSOA approach
Authors: Annapandi P. , Banumathi R. , Pratheeba N.S. , Manuela A. Amala
Published: June 2020

Due to the intermittent nature of renewable sources, the generation of power is varied which is the main problem in renewable energy system. Miss-matching between the power generation and load power causes a deviation from the desired voltage and frequency in power supply. Therefore, a new efficient smart grid system is required for an optimal power flow management. In this paper, a hybrid approach is presented for power flow management of HRES connected smart grid system. The novelty of the proposed approach is the combined execution of IHHO with SOA named as I2HOSOA technique. In the established work, the HHO is integrated by crossover and mutation function, it is known as IHHO. The main contribution of the proposed strategy is to control the power flow based on source and load side parameters variations. In the proposed approach, the control signals of the voltage source are developed by the IHHO based on the variety of power exchange between the source and load side. Similarly, the online control signals are located by the SOA procedure by utilizing the parallel execution against the active and reactive power varieties. The multi-objective function is shaped by the grid required active and reactive power varieties created based on accessible source power. Here, the control parameters of the power controller are enhanced by the proposed technique based control models in light of the power flow varieties. The comparison between established and existing methods is analyzed in terms of reactive current injection, grid code, current amplitude limitation control, active power control, zero active power oscillations, and injection of active and reactive power. Furthermore, the statistical evaluation of established, and existing methods of mean, median, and standard deviation, is evaluated. Finally, the proposed model is executed in MATLAB/Simulink working platform and the execution is compared with the existing techniques.