bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Four Competing Invasion Percolation Models for Gas Flow in Porous Media
Authors: Banerjee Ishani , Guthke Anneli , Ven Cole J.C. Van De , Mumford Kevin G , Nowak Wolfgang
Published: September 2023

Numerous variations of Invasion-Percolation (IP) models can simulate
multiphase flow in porous media across various scales (pore-scale IP to
macroscopic IP); here, we are interested in gas flow in water-saturated
porous media. This flow occurs either as continuous or discontinuous
flow, depending on the flow rate and the porous medium’s nature.
Literature suggests that IP models are well suited for the discontinuous
gas flow regime; other flow regimes have not been explored. Our research
compares four existing macroscopic IP models and ranks their performance
in these “other” flow regimes. We test the models on a range of
gas-injection in water-saturated sand experiments from transitional and
continuous gas flow regimes. Using the light transmission technique, the
experimental data is obtained as a time series of images in a
2-dimensional setup. To represent pore-scale heterogeneities, we ran
each model version on several random realizations of the initial entry
pressure field. We use a diffused version of the so-called Jaccard
coefficient to rank the models against the experimental data. We average
the Jaccard coefficient over all realizations per model version to
evaluate each model and calibrate specific model parameters. Depending
on the application domain, we observe that some macroscopic IP model
versions are suitable in these previously unexplored flow regimes. Also,
we identify that the initial entry pressure fields strongly affect the
performance of these models. Our comparison method is not limited to
gas-water systems in porous media but generalizes to any modelling
situation accompanied by spatially and temporally highly resolved data.
Effectiveness of a third dose of COVID-19 vaccines against delta variant of SARS-COV-2: A Serbian cohort study
Authors: Djordjevic Natasa , Matic Sanja , Milovanovic Dragan , Stefanovic Srdjan , Popovic Suzana , Todorovic Danijela , Djurdjevic Predrag , Sazdanovic Predrag , Antic Vasilije , Loncar Slavica , Bukumira Slavica , Radenkovic Marko , Sustersic Tijana , Filipovic Nenad , Baskic Dejan
Published: September 2023

Introduction/Objective. The duration of vaccine-induced protection against SARS-CoV-2 is shown to be limited. The aim of this study was to assess vaccine effectiveness (VE) of a third dose of four different COVID-19 vaccines during Delta variant predominance in Serbia. Methods. The data for the period from August 18, to October 1, 2021 were used to estimate the incidence rates (IR) of the SARS-CoV-2 infection, COVID-19-related hospitalization, and intensive care unit (ICU) admission. The study included 41,186 fully vaccinated subjects, of which 13,589 had received the third dose. VE was estimated based on the IR ratio following vaccination with three vs. two doses. Results. We found that a third dose of all investigated vaccines reduces the incidence of both SARS-CoV-2 infection and severe illness that requires hospitalization or ICU admission. The highest VE against infection demonstrated BNT162b2, followed by Gam-COVID-Vac and BBIBP-CorV. Third dose vaccination reduced the risk of hospitalization (IR = 0 for Gam-COVID-Vac and BBIBP-CorV), and ICU admission (IR = 0 for all vaccines). The hazard distributions for SARS-CoV-2 infection and hospitalization following vaccination with three versus two doses were significantly different. Conclusion. These findings indicate that an additional, third dose of studied vaccine boosters protection against all investigated outcomes.
Using Community Engagement Methods to Guide Study Protocol Decisions for School-Aged Children With Type 1 Diabetes
Authors: Abadula Fayo , C. Jordan Lori , LeStourgeon Lauren , S. Jaser Sarah
Published: September 2023

Introduction. Many challenges exist in developing multisite protocols for newly diagnosed children with type 1 diabetes. Our research team engaged community members to increase the likelihood of study success during a planning grant for a longitudinal study aimed at understanding risk and protective factors for neurocognitive function in school-aged children newly diagnosed with type 1 diabetes.

Methods. Two methods were used to obtain caregiver input into study protocol decisions. The first was a survey given to caregivers of children with diabetes (n = 21) about which aspects of the study protocol would make families more or less likely to participate. The second was a community engagement (CE) studio to obtain recommendations from a diverse group of caregivers of children with diabetes (n = 7) on key aspects of recruitment and enrollment.

Results. Results from both the survey and the CE Studio indicated that caregivers were interested and willing to participate in a longitudinal study of this nature. Both methods resulted in similar preferences for the type and amount of compensation, convenient study visits, flexible scheduling options, and receipt of neurocognitive test results. Recommendations from the CE Studio included additional strategies to minimize participant burden and enhance communication around study participation.

Conclusion. Both the feasibility survey and the CE Studio were useful mechanisms to obtain caregiver input during the study’s planning and design phase. Uniquely, the CE Studio approach offers researchers the ability to gain valuable community member input with minimal staff effort.
Use of the Multicriteria Decision Making Method in Establishing the Consequences of Breast Cancer Treatment
Authors: J Cvetkovic
Published: September 2023

Objective: We present in this paper the results of multicriteria ranking of risk factors for depression, anxiety and stress in women with breast cancer. Method: The PROMETHEE/GAIA method was used for ranking purposes, with additional optimization of alternatives using the PROMETHEE method with inherent limitations. Results: Almost 50% of women with early breast cancer experienced depression, anxiety or both in the period of one year after the diagnosis; 25% in the second, third and fourth year; and 15% in the fifth year. Long-term depression and anxiety were associated with prior psychological treatment, absence of an intimate, confident relationship, younger age and severely stressful (non-cancer) events in life. A lack of intimate support in confidence also predicted prolonged episodes of depression and anxiety. Conclusion: Increased levels of depression, anxiety or both in the first year after the diagnosis of early breast cancer indicate the need for special support services during that period. Psychological intervention for women with breast cancer who no longer have the disease should take into account a broader social context of cancer occurrence, with a focus on the improvement of social support.
Various Infections and Alzheimer's Disease
Authors: BAR Hassan
Published: September 2023

Alzheimer's disease (AD) is a major contributor to the worldwide prevalence of dementia. Extracellular-amyloid (A) senile plaques (SP) and intracellular neurofibrillary tangles (NFT) are the neuropathological hallmarks of Alzheimer's disease. Currently, it is believed that both hereditary and environmental variables interact to contribute to the pathophysiology of AD. Despite significant investments in neurological research, the precise molecular basis of AD pathogenesis remains unknown. Multiple studies point to the possibility that pathogenic microorganisms contribute to the development of AD. Microbes were formerly thought to have no connection to Alzheimer's disease, but a rising body of research suggests otherwise. Evidence that these microbes cause AD-specific cognitive and neuropathological deficits and changes is lacking, casting doubt on the hypothesis that AD is an infectious neurological illness. In addition, the gut flora may have a role in AD progression in humans.
Nasopharyngeal Carcinoma (NPC) in Russia and Epstein - Barr Virus Types: Analysis of the Influence of Gender, Ethnic and Age Factors on the Virus Types Spread in NPC Patients
Authors: VE Gurtsevitch
Published: September 2023

Introduction: The discovery of two molecular types of Epstein-Barr virus, EBV-1 and EBV-2, with different biological properties, stimulated the search for new neoplasms associated with each type of the virus. Objective: The aim of this study was to analyze the prevalence of EBV-1 and EBV-2 in NPC patients from different climatic and geographical regions of Russia, representatives of different gender, ethnic and age groups of patients. Materials and Methods: Using nested PCR EBV types were determined in blood plasma of NPC and other non-EBV-associated tumors of the oral cavity (OTOC/EBV-) patients from the North Caucasus (NCFD) and the Central (CFD) Federal Districts of Russia. IgG and IgA antibody titers to viral capsid antigen (VCA) were determined by indirect immunofluorescence. Results: The studies carried out have shown that NPC and OTOC/EBV- patients were infected with both EBV types in roughly the same ratio. There were also no statistically significant differences in serological activities of NPC patients infected with EBV-1 or EBV-2. The prevalence of EBV-2 types 1 and 2 was not influenced by gender or ethno-geographic affiliation of NPC patients. The only difference was EBV-2 predominance in NPC patients under 60, and EBV-1 predominance in those over 60 years old. Conclusion: The absence of a predominance of one of the EBV types in NPC patients indicates that neither EBV-1 nor EBV-2 is strictly NPC-associated in Russia, and that different ethnic and climatic-geographical factors in the spread of virus types in NPC patients are not playing an essential role.
Novel Corona Turkish Novel Protocol
Authors: AG Sahan
Published: September 2023

Aim: To share a novel corona treatment method that is effective on patients with the scientific community. Introduction: The new corona infection has caused a different fear all over the world, and many studies have been conducted to prolong the lives of patients who die from complications or while being treated. Materials & Methods: Among the 2000 patients who were admitted to the service(500), outpatient clinic(1420) and hospitalized in intensive care (80), 147 patients who were examined naively during the period 1.2.2021-1.4.2021 were included in the study cross-sectionally. Patients at risk of death in intensive care and pre-treatment protocols at varying rates depending on the different age. Regarding the diagnosis and treatment of the disease; Since it is known that even the effects of drugs that cause complications cause human death, it was prioritized to make the treatment plan accordingly and pay attention to the complications of these treatments. The patient, whose problems with hydroxychloroquine, favipiravir and other protocols are recovering, can lead to lung edema, intubation in the intensive care unit and subsequent death. Although the complications and mortality rate of the disease is not more than influenza, it seems possible to prevent some of the deaths. The age of patients’ distrubition 5 from 94 years old, avarage age 42 years old. drugs used in treatment planning, D vitamins single dose and zinc , tigacycline , vancomycin (renal function controlled), meropenem 1 gr (renal function controlled),enoxaparin (renal function controlled) pantoprasol , 4 gr ascorbic acid will be infused,dexamethasone , budesonide. If there is an increase in the response to antibiotherapy, ivermectine therapy, tocilisumab treatment should be added without delay. tocilisumab therapy ; tocilisumab and ivermectine treatment of patients will be consideredaccording to crp decrease. Result: The patient is treated and remains normal for three days, the patient can be discharged. There was no need for tocilizumab treatment on the patients did not use favipiravir treatment among were followed up. Longest treatment protocol is completed 21 days; shortest treatment protocol is completed 3 days. No additional complications were encountered in 800 cases treated and patient follow up completed. Discussion: While researching different treatment protocols in a new viral infection, it is a wrong practice to try new drugs rather than to cure the patients. Trying to treat patients with medications that have not been followed up and tried clearly makes more harm than normal. For this reason, it preparing protocols with known drugsare vital and not to use experimental antivirals (favipiravir, remdesivir, oseltamivir etc) that did not work in previous outbreaks.
Greenhouse gas and reactive N-gas emissions from a horse paddock – relationship to physicochemical properties of soil
Authors: Maljanen Marja Elisa , Marttila Emilia , Bhattarai Hem Raj
Published: September 2023

The horse industry today in Europe is an increasing leisure or sporting activity. Due to considerable input of nutrientsvia dung and urine, horse paddocks can be significant sources of greenhouse gases (GHG) and reactive nitrogen (N)-gases. However, horse paddocks have not been studied intensively in contrast to e.g., dairy cow pastures. Here we report GHG emissions from one selected horse paddock in Eastern Finland. During the first year, GHG emissions from the site and surrounding grassland area were measured with closed static chamber method. In the following year soil samples were taken from the sites to study GHG emission and reactive N-gas (nitrous acid and nitric oxide) emissions in the laboratory. The paddock area emitted significant amounts of N-gases and methane compared with surrounding areas during wet season. N-gas emissions also increased with increasing soil mineral N concentration. We conclude that horse paddocks can be significant but local sources of greenhouse gases and wet soil conditions should be avoided to mitigate the emissions.
Material Agency of Crystals in New Spirituality
Authors: Teidearu Tenno
Published: September 2023

This paper studies crystals in New Spirituality in Estonia not only as things, or objects, used in certain practices, but also as agentive materials. My research participants, who wear crystals, take their material properties seriously, finding the properties to have supportive qualities, according to esoteric interpretation. Nevertheless, things and materials, objects and minerals, are never permanent; they have material lives of their own. Sometimes minerals lose their gloss, crack, break or just become lost. Physical decay and displacement, which are the focus of this paper, have meaning-making potential, which my interlocutors interpret within the framework of the esoteric. Their perception of these minerals can be understood in posthumanist and new materialist terms. The paper uses the concept of material agency to demonstrate how natural processes of decay acquire cultural meaning by connecting material properties and human interpretation.

This work was supported by an Estonian Research Council grant (PUT number PRG670), ‘Vernacular Interpretations of the Incomprehensible: Folkloristic Perspectives Towards Uncertainty’.
Enhancing Adaro’s Transformation Strategy for Business Diversification: The Aluminium Smelter Project
Authors: Effendi Mohammad , Putro Utomo Sarjono
Published: September 2023

Climate change has become a global concern, and at the 21st Conference of Parties (COP 21) held in Paris in 2015, participating countries agreed to phase out fossil fuels and replace them with renewable energy to achieve Net Zero Carbon Emissions by 2060. Adaro Energy Indonesia (AEI) is a coal (Fossil Fuel) producing company, and the company has prepared a business diversification to a non-coal business. The first step is business diversification for the Aluminium Smelter project. This paper focuses on enhancing Adaro’s transformation strategy for its ongoing business diversification efforts, specifically the Aluminium Smelter Project (Adaro, 2023). It explores the current state of Adaro's transformation, identifies areas for improvement, and provides strategic recommendations to strengthen the transformation strategy. The assessment uses Michael Porter’s Five Forces theory for market analysis, the PESTLE theory for external scanning analysis, and the Organizational Change Management theory for organisation analysis. These theories together are used to capture Adaro’s ideal transformation strategy conditions. SWOT and Resource-Based View (RBV) theories are applied to evaluate existing AEI’s organisational strengths. By comparing the ideal transformation strategy conditions with the current situation of AEI, areas that require enhancement are identified. By refining this strategy, the author is confident that Adaro will successfully navigate the business diversification process and capitalize on the opportunities presented by the Aluminium Smelter Project.
Main results of supplementary comparisons of high voltage and current measuring systems
Authors: Velychko Oleh , Kikalo Valeriy , Anokhin Yurii , Gordiyenko Tetyana
Published: September 2023

High voltages of alternative current (AC) are important because they are needed for numerous applications in physics and engineering. High AC voltages are also used to test insulating materials for their dielectric properties. Calibrations of instruments for high-voltage measurements should provide metrological traceability to national standards. This applies to the requirements for both voltage measuring instruments and current measuring instruments. The transformer for high-voltage measurements is used to reduce the values of currents and voltages during measurements in high-voltage electrical networks.

Voltage transformers (VTs) are used to accurately measure high AC voltages. Current transformers (CTs) are used to convert line currents in power systems to levels that are acceptable for other measuring instruments, which are necessary to trip protective devices. There are measuring installations that are well known for accurate measurements of the CT coefficient for large primary currents, and systems for determining the behaviour of the industrial current and VT under distorted waveforms, etc. The calibration of a high voltage measuring system must be traceable to national or international measurement standards. Mutual comparisons of calibration results of CT and VT standards are carried out with the participation of several national laboratories.

The results of high voltage transformer measuring systems (GULFMET.EM-S6) and high current transformer measuring systems (GULFMET.EM-S7) supplementary comparisons are described. The comparisons were carried out between national laboratories from three Regional Metrology Organizations. In general, the participants of both comparisons have demonstrated a good agreement of the results in the ratio error and phase displacement for high voltage and current. The comparison results may be used to improve the participants’ existing calibration and measurement capabilities entries in the Key Comparison Database (KCDB) of the International Bureau of Weights and Measures  (BIPM).
Assessment of metastatic traits of the cells with hybrid phenotype in breast cancer
Authors: Mukhamedzhanov RK , Grigoryeva ES , Tashireva LA , Perelmuter VM , Zavyalova MV , Savelieva OE
Published: September 2023

Nowadays, great attention is paid to the study of circulating tumor cells (CTCs) due to their key role in distant metastasis. At the same time there is little data on the properties of circulating cells showing simultaneous expression of the leukocyte and epithelial markers and their possible role in tumor progression and chemotherapy resistance. The study was aimed to assess subpopulations of cells with hybrid epithelial/leukocyte phenotype and estimate the features of stemness, epithelial–mesenchymal transition (EMT), and integrin interface, which determine the cells’ possible metastatic properties in breast cancer (BC). The survey data from 128 patients with invasive breast carcinoma of no special type were included. Multicolor flow cytometry was used to assess the population structure and metastatic potential of the cells circulating in blood and primary tumor cells with hybrid phenotype. The primary tumor cell suspension was prepared by mechanical disaggregation. The high degree of heterogeneity was noted in the population of cells with hybrid phenotype, including the combination of the stemness and EMT features, and diverse integrin interface. Cells with hybrid phenotype are involved in the mechanisms underlying lymph node and distant metastasis. In lymph node metastasis, metastatic potential of these cells is associated with the stemness features (р = 0.0422) and co-expression of β3-, β4-, and αVβ5-integrins (р = 0.0338). In distant metastasis, metastatic potential of hybrid cells is associated with the stemness features (р = 0.015) and is not associated with the EMT features and integrin expression.
Unveiling ZrO2/natural zeolite catalytic performance on hydrocracking palm oil mill effluent residue
Authors: Layla Sihombing Junifa , Herlinawati Herlinawati , Nasir Pulungan Ahmad , Kembaren Agus , Saragih Gimelliya , Harmileni Harmileni , Rahayu Rahayu , Anggara Wibowo Ary
Published: September 2023

Palm oil mill effluent (POME) is the largest liquid waste from crude palm oil production. This liquid waste still contains a lot of chemical components, solid deposits, and oil which is dangerous if released directly into the environment. The residual oil and grease components contained in POME can be further extracted and converted into fuel fractions. This study investigates the conversion of residual oil from POME into fuel fractions through hydrocracking. A ZrO2/Sarulla natural zeolite (SNZ) catalyst was used, characterized by a particle size of 1-1.5 µm, a surface area of 73.3 m2/g, a pore volume of 0.161 cc/g, and a pore diameter of 3.35 nm. The effect of catalyst mass was studied, with the total conversion increasing to a certain extent with increasing catalyst mass, however, an increase in coke formation decreased the product yield. The highest gasoline fraction selectivity was obtained with a catalyst mass of 0.09 wt% (~42%), while the kerosene fraction was most obtained with a catalyst mass of 0.15 wt% (~40%). The liquid product with a catalyst mass of 0.15 wt% had the highest HHV of 44.2 MJ/kg, a 12% increase from the HHV of POME oil residue (39.4 MJ/kg). The results demonstrate the potential of using residual oil from POME as a source for fuel production and the use of natural zeolite-based catalysts as hydrocracking catalysts.
Chemistry teacher and pre-service chemistry teacher views: Can social media be used as chemistry learning media?
Authors: Syahidul Shidiq Ari , Yamtinah Sri , Retno Widarti Hayuni
Published: September 2023

Chemistry learning should be able to integrate contextual chemistry problems and present the sophistication of 21st-century learning technology. As a product of 21st-century technology, social media can be used as chemistry learning media. Therefore, this study aims to investigate the views of chemistry teachers and pre-service chemistry teachers toward the potential use of social media as chemistry learning media. The Purposed-designed survey method that involved 76 chemistry teachers and 109 pre-service chemistry teachers as respondents was used in this study. A total of 40 question items were developed and distributed online using a Google form to respondents. Based on the results of the survey conducted, it is known that during online and offline chemistry learning, respondents are accustomed to using YouTube as chemistry learning media. In addition, Instagram is the social media most widely owned by pre-service chemistry teachers, while Facebook is the social media most commonly owned by chemistry teachers. Other results reveal that most respondents have the same screen time, more than 4 hours daily. This screen time is used by respondents for entertainment and looking for news information on social media. With this long screen time not used for learning, it can be a promising opportunity to use social media as chemistry learning media. This study is expected to be a reference for developing social media-based chemistry learning to increase student motivation and achievement.
Molecular docking analysis of six major compounds from sweet basil (Ocimum basilicum L.) extract as potential anti-hypertension therapy
Authors: Cakra Buana Bayu , Iksen Iksen , Gurning Kasta
Published: September 2023

Hypertension is an abnormally high blood pressure condition that is the leading cause of preventable cardiovascular disease, chronic kidney disease, and cognitive impairment. In the case of hypertension, repressing the Angiotensin-Converting Enzyme (ACE) expression has been shown to be an effective method of controlling hypertension by inhibiting the conversion of angiotensin I to angiotensin II. Captopril is the most commonly used ACE inhibitor. It simultaneously inhibits the conversion of angiotensin I to the potent vasoconstrictor angiotensin II and the vasodilator peptide bradykinin. Sweet basil (Ocimum basilicum L.) on the other hand, is used in traditional Indian and Chinese medicine to treat a variety of diseases, including hypertension. The study aimed attempts to investigate the potency of 6 major compounds found in sweet basil (Ocimum basilicum L.) extract, as an anti-hypertension therapy. The analysis demonstrates that Ocimum basilicum L., extract is effective as an anti-hypertension therapy because it contains several compounds that may interact with ACE and inhibit its activity. The molecular docking analysis and drug-likeness prediction indicate that camphor could be a potential drug candidate because it does not violate the Lipinski rule, has a high Gastrointestinal (GI) absorption, a high affinity to interact with ACE, and a similar interaction site to the ACE-Captopril interaction.
Development of modules macromolecules based on local natural resources of Maluku in project-based learning for XII grade senior high school students
Authors: Salelatu Vivian , Rohaeti Eli
Published: September 2023

This research aims to develop chemistry learning modules based on local natural resources in Maluku in project-based learning on macromolecular material class XII IPA SMA. This research refers to the 4-D development model by Thiagarajan, Semmel, and Semmel, which includes the stages of define, design, develop, and disseminate. This learning module has gone through the validation stage by expert validators. It has gone through field trials and has been revised by developers to produce a valid and practical learning module. The results of this study are: (1) validity assessment by one media expert and one material expert is in the very valid category with an average score from material experts of 4.49 and an average score from media experts of 4.68; (2) the small group trial to 9 students of class XII IPA 1 SMAN 6 Ambon obtained a percentage of 93.6% in the very practical category; (3) Field trials to 30 students of class XII IPA 3 SMAN 12 Ambon resulted in a percentage of 90.2% with a very practical category. The response of five chemistry teachers to the developed module also resulted in a percentage of 85.4% in the very practical category. In conclusion, the chemistry learning module based on local natural resources in Maluku in project-based learning developed with a 4-D model is valid, practical, and It can be used as teaching materials in school.
The effectiveness of flipped classroom on scientific literacy and critical thinking improvement
Authors: Wijayanto Nur , Gani Abdul , Hasan M. , Widowati Asri
Published: September 2023

Scientific literacy has a vital role in supporting 21st-century skills. Good literacy skills can directly affect students' thinking abilities, which makes them more creative in solving problems. The low ability of students' scientific literacy and critical thinking is still a problem in the world of education. The application of appropriate learning models and methods can improve student learning outcomes. The goal of this study was to see how the flipped classroom learning model affected the literacy and critical thinking skills of SMAN 3 Yogyakarta grade XI students. The pretest-posttest control design experimental method was carried out on a total of 35 samples from a population of 213 students. The results of the Mann Whitney and Wilcoxon tests obtained a significance of less than 0.05 in both the control and experimental groups for pretest and posttest values. The use of the flipped classroom method effectively improved scientific literacy and critical thinking skill. There is a strong relationship between critical thinking skills and scientific literacy.
Scientific attitudes in chemistry learning: A systematic literature review
Authors: Shanderi Intan , Suwardi Suwardi
Published: September 2023

This systematic review analysis study aimed to examine the scientific attitudes in chemistry learning. The method used a Systematic Literature Review which consists of 5 stages adopted from Denyer and Tranfield. The main criteria for the selection of articles are scientific attitude in the field of chemistry learning with a period of 2012 until 2023 from the well-known national and international database. There were 29 articles were obtained that fit into the criteria. The article’s aspect focused on the parameters such as aim, sample level, instructional method, instruments, and chemistry subject. The result showed that the attitude scale is the most instrument that can be used to measure scientific attitude in chemistry learning. Meanwhile, PBL has become the most instructional method that has been used to enhance scientific attitude. Moreover, the studies mostly aim to investigate the influence of teaching methods on scientific attitudes. Most researchers involve high school students in scientific attitude research on analytical chemistry concepts. There are different codes for each theme of scientific attitudes. Thus, the review helps to evaluate the instrument and instructional methods in chemistry learning and also provides recommendations for examining students’ scientific attitudes in further explorations.
Joanna Nowotny & Julian Reidy. Memes – Formen und Folgen eines Internetphänomens
Authors: Johann Michael
Published: September 2023

Memes – Formen und Folgen eines Internetphänomens [Memes – Forms and Consequences of an Internet Phenomenon] is a monograph in the German language authored by Joanna Nowotny and Julian Reidy. In the introduction, five main chapters, and a conclusion, the authors tackle a relatively young, but booming phenomenon of digital culture and communication: Internet memes. The book provides valuable insights and perspectives on the ever-evolving dynamics of memes and meme culture, and it successfully provides a well-executed counterpoint to often overly romanticized meme literature by shedding light on the “darker” aspects of meme communication. While many previous publications tend to idealize memes, this book takes a courageous step in examining the potential negative implications and consequences associated with their spread. By focusing on the less explored, sometimes problematic, and even controversial aspects of meme culture, the book presents a comprehensive view of the impact of memes.
EFECTO DE LOS FACTORES CLIMÁTICOS DETERMINANTES SOBRE LA PRODUCCIÓN DE Myrciaria dubia (Kunth) McVaught EN UCAYALI, PERÚ, 2009 – 2029
Authors: PANDURO-TENAZOA Nadia Masaya , RAMÍREZ-FLORES Noé , LÓPEZ Y MORALES Javier Gonzalo , PINEDO-PANDURO Mario , HUAMANÍ-YUPANQUI Hugo Alfredo , ABANTO-RODRÍGUEZ Carlos , COLLAZOS SALDAÑA Herman
Published: September 2023

La producción agrícola es sensible a los factores climáticos y el estudio de sus relaciones es fundamental para comprender su comportamiento a futuro; por ello, el objetivo de este estudio fue determinar el efecto de los factores climáticos determinantes en la producción de Myrciaria dubia (Kunth) McVaugh, en Ucayali – Perú, 2009-2019; para ello, mediante la función de producción se cuantificó el efecto de los factores climáticos (temperatura y precipitación pluvial) determinantes sobre la producción del camu-camu en Ucayali; considerando para ello, como dimensiones de la producción: rendimiento por hectárea (t.ha-1), superficie cosechada (ha) y el valor bruto de la producción (soles) del periodo 2009 – 2019 y su proyección hasta el 2029, utilizando el método de Mínimos Cuadrados Ordinarios (MCO). Se pudo determinar que la precipitación pluvial es el factor climático con mayor importancia sobre el rendimiento con un 48,79%; y que, al 2029 la tendencia de su rendimiento es negativo, con una reducción de 1,12 t.ha-1. Por otro lado, la temperatura máxima es el factor climático determinante sobre la superficie cosechada del camu-camu en 68,82%; al 2029 su proyección es positiva con un incremento de 835,50 ha. Así también, la temperatura máxima es el factor climático determinante sobre el valor bruto de la producción de camu-camu a un 82,62% y al 2029, su proyección será positiva con un incremento de 3 546 843,95 soles.
Mantle convection and diamonds
Authors: Puchkov V. N. , Zedgenizov D. A.
Published: September 2023

Research subject. The present evolutionary stage of geodynamic theory is associated with the idea of thermochemical convection of various levels in the Earth's mantle, where the centrifugal branches are represented by plumes, and the centripetal - by subduction zones. Aim. The study of diamonds contributes to an understanding of when, at what level in mantle, under what P-T conditions and geochemical environment particular diamonds originated, which were then transported by centrifugal convection flows to the Earth's surface, thereby permitting characterization of this flow. Materials and methods. Generalization of published materials and characterization of mineral inclusions in diamonds allow the general structure of mantle convection to be clarified in different epochs and different regions. Results. The data obtained on mineral inclusions in diamonds, along with the experimental data on the P-T conditions of their mineral parageneses and geophysical data on mantle properties, indicate that the depth of diamond formation varies from the lower lithosphere in the upper part of the upper mantle (≈150-250 km) to the bottom of the lower mantle. At the same time, the diamonds containing mineral inclusions, characteristic of the lower mantle, account for only the first percents of the general number of diamonds. Conclusions. The transport of diamonds from different depths of their origin is a reliable indication of convection processes (as a plume activity) in the mantle. This information provides evidence to the real existence of plumes, which is important in the context of ongoing discussions on the depth of their origin. However, the study of mineral inclusions in diamonds, particularly in superdeep diamonds, is a challenging task due to the retrograde changes, resorption and sometimes complete dissolution on their way to the surface. These circumstances minimize the probability of occurrence of superdeep diamonds and require consideration when making judgements about the reality of existence of superdeep diamonds.
Emotions in Crisis: Consequences of Ceremonial Refugee Camp Visits to Bhutanese Refugee Camps in Nepal
Authors: Warren Kamryn
Published: September 2023

Research on refugee resettlement frequently overlooks the larger context of the experience of forced migration. As a result, the micro-level interactions between refugees and the bureaucrats who make resettlement decisions are obscured. We can better understand the socio-political dynamics between refugees and the officials deciding their resettlement cases if we approach encounters between refugees and migration officials during ceremonial visits as sites of emotional exchange. This article examines the complex socio-political emotional exchanges of power and vulnerability that underpin the refugee resettlement process through an ethnographic analysis of Bhutanese refugee camps in Nepal.
Os inibidores seletivos de recaptacão de serotonina no tratamento do transtorno do pânico: uma revisão sistemática de estudos placebo-controlados
Authors: Mochocovitch Marina Dyskant , Nardi Antonio Egidio
Published: September 2023

Introdução: O transtorno do pânico (TP) é uma condição com alta prevalência na população e elevada morbidade. Os inibidores seletivos de receptação de serotonina (ISR$) são medicamentos vastamente utilizados na prática clínica para o tratamento deste transtorno. Objetivo: Realizar uma revisão sistemática atualizada dos estudos publicados que comparem de forma duplo-cega e randomizada o efeito dos ISRS versus o efeito placebo no TP e descrever o mecanismo de ação desta classe medicamentosa nos sintomas de ansiedade. Metodologia: A revisão sistemática foi realizada nas bases Medline/ PubMed" e “Web of Science - ISI”, utilizando como palavras-chave para busca os termos Mesh: panic disorder, placebo, fluoxetine, sertraline, paroxetine, citalopram, escitalopram e fluvoxamine. Resultados: Foram incluídos 11 estudos e todos demonstram a superioridade dos ISRS com relação ao placebo, apesar de ter sido constatado importante efeito placebo nos pacientes com TP. Conclusão: A ação inibitória da serotonina na panicogênese vem sendo confirmada por diversos estudos. Os ISRS são uma classe medicamentosa eficaz para o tratamento do TP e estudos placebo-controlados são importantes para esta avaliação. Não há evidência de eficácia diferencial entre as drogas desta classe. Estudos controlados de longo prazo ainda são necessários para avaliar os efeitos da continuidade destas medicações por períodos prolongados.
Cérebros, máquinas e psiquiatria [psiquiatria computacional]
Authors: Camara Fernando Portela
Published: September 2023

A ideia de que os processos mentais são computacionais e, portanto, reprodutíveis artificialmente trouxe um grande impulso para a criação da Inteligência Artificial e se tornou um marco teórico que revitalizou a psicologia cognitiva, o conexionismo, a linguística, engenharia biomédica e outros campos. A psiquiatria é uma disciplina que muito se aproxima da ciência computacional e sua interação com essa campo científico é um fator de desenvolvimento e evolução para essa especialidade médica. Nesse artigo discutimos alguns aspectos teóricos e algumas propostas de modelos para o que podemos chamar de psiquiatria computacional.
Effect of Foot Reflexology on Anxiety Levels among Patients to Receive Cardiac İmplantable Electronic Devices: A Randomised Controlled Study
Authors: Çuvadar Ayşe , Aksoy Berna , Yıldız Umut , Öztürk Cihan
Published: September 2023

The aim of this study was to determine the effect of foot reflexology, a complementary and supportive method on anxiety in patients scheduled to receive cardiac implantable electronic devices. This randomised controlled study was conducted between April 2022 and October 2022 at the cardiology clinic of a university health research and application centre in Turkey. The study was conducted with 64 patients—32 in the experimental and 32 in the control group. Data were collected using a patient information form and the Spielberger State-Trait Anxiety Inventory (STAI). A significance level of p < 0.05 was accepted. The results showed that the mean scores of the State Anxiety Inventory were significantly higher in the experimental group than in the control group, and the mean scores of the Trait Anxiety Inventory were significantly lower in the experimental group than in the control group (both p < 0.001). These findings indicate that the intervention in the experimental group led to a significant decrease in anxiety levels. This study demonstrated that foot reflexology significantly affected anxiety in patients planning for cardiac implantable electronic devices. The participants in the experimental group had significantly higher state anxiety levels than those in the control group after the intervention, but their trait anxiety levels were significantly lower than those in the control group after the reflexology application.
Basic Psychological Needs Assessment of University Students in Bangladesh
Authors: Hoque Muhammad , Uzzaman Muhammad Akram , Zungu Lindiwe
Published: September 2023

The mental health of university students is a worldwide concern whose effects include, among others, inability to study, poor memory, reduced focus, attention, and fatigue. Mental health difficulties are also regarded as the leading cause of despair, depression, anxiety, and suicide among university students. This research aimed to assess the basic psychological needs of undergraduate students from a selected university in Bangladesh. This was a cross-sectional quantitative study conducted among 174 students who were selected randomly. Data were collected using a self-administered questionnaire. The following dimensions were measures to assess the basic psychological needs: relatedness, competence, autonomy, positive emotion, and intrinsic learning motivation, and self-regulated learning. The overall psychological well-being of the students was found to be poor. Female students had significantly higher mean scores for competence and motivation (p < 0.05). Year of study and faculty were significantly associated with relatedness, competence, autonomy, positive emotion, and intrinsic learning motivation (p < 0.05). The current study emphasises the significance of perceived competence, autonomy, and self-regulated learning for the well-being of university students. The findings also suggest that relatedness may be relevant for intrinsic learning motivation.
Drawing a “Perfect Circle”: How Clinicians Can Become Better Communicators
Authors: Peterson Seth , Miciak Maxi , Kleiner Michelle , Woolf John , Davenport Todd
Published: September 2023

SYNOPSIS: Despite the importance of communication in person-focused care, biomedical knowledge and technical skill development are often prioritized in physical therapy education. As clinicians and educators, we contend that mindfulness and reflection nurture effective communication approaches and support physical therapists in navigating the complexity and uncertainty that comprise most clinical interactions. We suggest that clinicians be mindful of the self, the patient, and the context when interacting with patients. Although being mindful cultivates awareness and curiosity, being reflective is an active practice that can be used while deliberating about the right thing to do or say in a particular situation. In this Viewpoint, we offer clinicians and educators suggestions for engaging in mindful and reflective practices. Through the contemplative practices of mindfulness and reflection, clinicians can better cultivate their communication expertise and good practice. J Orthop Sports Phys Ther 2023;53(10):579-584. Epub: 8 September 2023. doi:10.2519/jospt.2023.11917
Football Players With Hip Dysplasia: The Relationship Between Muscle Strength, Functional Performance, Self-reported Sport and Recreation, Cartilage Defects, and Sex. A Cross-sectional Study
Authors: O’Brien Michael J.M. , Kemp Joanne L. , Semciw Adam Ivan , Mechlenburg Inger , Jacobsen Julie S. , King Matthew G. , Scholes Mark J. , Lawrenson Peter R. , Crossley Kay , Agricola Rintje , Souza Richard B. , Heerey Joshua
Published: September 2023

OBJECTIVE: In symptomatic football players with hip dysplasia, we aimed to explore the relationships between self-reported sport and recreation ability and (1) hip muscle strength, (2) functional performance, and investigate if these relationships were modified by sex or cartilage defects.

METHODS: In this cross-sectional study, football players (n = 50) with longstanding (>6 months) hip and/or groin pain, a positive flexion/adduction/internal rotation test, and a lateral-center-edge angle <25° were included. Hip muscle strength and functional performance were assessed. Self-reported sport and recreation ability was quantified using the sports and recreational subscales from the International Hip Outcome Tool-33 (iHOT-Sport) and the Copenhagen Hip and Groin Outcome Score (HAGOS-Sport). Relationships were evaluated using regression models with sex and cartilage defects as potential effect modifiers.

RESULTS: There was a positive linear relationship between the one-leg-rise test and the iHOT-Sport subscale (β = 0.61; 95% CI: 0.09, 1.14). A polynomial (concave) relationship was found between peak eccentric adduction strength and the HAGOS-Sport subscale (β = −30.88; 95% CI: −57.78, −3.99). Cartilage defects modified the relationship between peak isometric adduction strength and HAGOS-Sport, with those with cartilage defects having a polynomial (convex) relationship (β = 36.59; 95% CI: 12.74, 60.45), and those without cartilage defects having no relationship.

CONCLUSION: One-leg-rise performance and adduction strength were associated with self-reported sport and recreation ability, indicating a possible relationship between physical function, hip joint structure, and sport and recreation ability in football players with hip dysplasia. J Orthop Sports Phys Ther 2023;53(10):626-633. Epub: 8 September 2023. doi:10.2519/jospt.2023.12026
Effectiveness of Exercise Interventions for Preventing Neck Pain: A Systematic Review With Meta-analysis of Randomized Controlled Trials
Authors: Teichert Florian , Karner Vera , Döding Rebekka , Saueressig Tobias , Owen Patrick J. , Belavy Daniel L.
Published: September 2023

OBJECTIVE: To update the evidence on the effectiveness of exercise interventions to prevent episodes of neck pain.

DESIGN: Systematic review with meta-analysis.

LITERATURE SEARCH: MEDLINE, Embase, CENTRAL, CINAHL, SPORTDiscus, PEDro, and trial registries from inception to December 2, 2022. Forward and backward citation searches.

STUDY SELECTION CRITERIA: Randomized controlled trials (RCTs) that enrolled adults without neck pain at baseline and compared exercise interventions to no intervention, placebo/sham, attention control, or minimal intervention. Military populations and astronauts were excluded.

DATA SYNTHESIS: Random-effects meta-analysis. Risk of bias was assessed using the Cochrane RoB 2 tool. The certainty of evidence was judged according to the GRADE approach.

RESULTS: Of 4703 records screened, 5 trials (1722 participants at baseline) were included and eligible for meta-analysis. Most (80%) participants were office workers. Risk of bias was rated as some concerns for 2 trials and high for 3 trials. There was moderate-certainty evidence that exercise interventions probably reduce the risk of a new episode of neck pain (OR, 0.49; 95% confidence interval: 0.31, 0.76) compared to no or minimal intervention in the short-term (≤12 months). The results were not robust to sensitivity analyses for missing outcome data.

CONCLUSION: There was moderate-certainty evidence supporting exercise interventions for reducing the risk for an episode of neck pain in the next 12 months. The clinical significance of the effect is unclear. J Orthop Sports Phys Ther 2023;53(10):594-609. Epub: 8 September 2023. doi:10.2519/jospt.2023.12063
A rare case of a right infratentorial meningioma and a left giant posterior communicating thrombosed aneurysm
Authors: Lara-Olivas Jorge Armando , Sangrador-Deitos Marcos V. , Villalobos-Díaz Rodolfo , Marian-Magaña Ricardo , Gomez-Amador Juan Luis
Published: September 2023

Background:

Giant intracranial aneurysms cause symptoms due to mass effect and can mimic other lesions in imaging studies. The coexistence of tumors and aneurysms is relatively rare, with meningiomas being the predominant tumors found in such cases. The relationship between these two entities is complex and represent a neurosurgical challenge.

Case Description:

A 61-year-old woman presented with intermittent headache, vertigo, right peripheral facial palsy, hearing loss, and left hemiparesis. Magnetic resonance imaging revealed two lesions: a supratentorial paraclinoid lesion in the left frontotemporal region and a right infratentorial extra-axial mass, suggestive of a meningioma. The patient underwent a two-staged surgical intervention to address both lesions.

Conclusion:

In this particular case, the lesions were located on different sides and in different cranial compartments, making it even rarer.