bluuebunny/crossref_metadata_2025 huggingface dataset:
Древнетюркский топоним Qadïrqan и его возможные соответствия в современных языках Саяно-Алтайского региона
Authors: Simchit Kyzyl-Maadyr A.
Published: September 2018

В статье рассматривается древнетюркский топоним qadïrqan и его возможные соответствия в современных языках Саяно-Алтайского региона. Автор предполагает, что лексему qadïrqan можно сопоставить с хайыракан, в той или иной форме и значении распространенной в некоторых современных языках данного региона.Гор, имеющих в названии компонент хайыракан в Туве несколько, все они для тувинцев являются священными. Автор подробно останавливается на употреблениях слова в тувинских фольклорных текстах, в частности связанных с шаманскими верованиями и пр. Отмечается широкое употребление рассматриваемой лексемы при эвфемистическом обозначении медведя в тувинском языке. Рассматривается версия, утверждающая монгольское происхождение лексемы. Приводя в доказательство различные формы и значения данного слова (или их компонентов) в языках региона, автор предполагает: сопоставление древнетюркского qadïrqan и лексемы хайыракан имеет под собой твердую основу.Сопоставление qadïrqan / хайыракан возможно с точки зрения фонетических законов. Переход интервокального -д- / -й- в начальном слоге — характерная черта древних тюркских, возможно и монгольских, языков. Кроме того, возможно и семантическое сопоставление. Древнетюркская qadïrqan и лексема хайыракан оба имеют прямое отношение к горам. Мотивация подобного почтительного обращения к горам без сомнения была актуальной не только для монголов, но для древних тюрков и предков тувинцев эпохи феодализма.Таким образом, автор полагает, что древнетюркский топоним qadïrqan в средневековье, в период монгольского владычества, был заимствован монгольскими племенами. И от них перешел в некоторые языки тюркско-монгольской контактной зоны, в том числе в тувинский язык, где прочно и глубоко вошел в его лексический состав.
Топонимические предания и легенды Юго-Восточной Тувы
Authors: Dongak Antonina S.
Published: September 2018

В статье анализируется локальное своеобразие сюжетов и мотивов топонимических преданий Юго-Восточной Тувы: Тес-Хемского, Эрзинского и Тере-Хольского кожуунов (районов). Учитывается контекст этнокультурных связей тувинцев региона с монголами — жителями соседней Западной Монголии. Юго-Восточная Тува рассматривается как территория тувинско-монгольского двуязычия, которое составляет колорит его локальной культуры. Материалом послужили образцы легенд и преданий, изданные в различных сборниках тувинского фольклора, а также полевые записи совместной тувинско-монгольской научной экспедиции в Эрзинский кожуун Республики Тыва в 2011 г., в которой принимала участие автор.В Юго-Восточной Туве проживают тувинские родоплеменные группы кыргыс, соян, чооду, среди которых с разной степенью распространен тувинско-монгольский билингвизм. Бытование монгольского языка у них сегодня является культурным реликтом.В локальной устной традиции Юго-Восточной Тувы бытуют легенды (тоолчургу чугаа — сказочное повестование), предания (төөгү чугаа — исторический рассказ) и устные рассказы (болган таварылга — былички). Среди них значительное место занимают рассказы, объясняющие происхождение названий разных географических объектов местности —топонимические предания. Им присущи следующие черты: отсутствие четкой композиционной структуры, одноэпизодность, локализация места и времени события, ссылка на конкретных свидетелей и участников, ориентированность на историзм и достоверность сведений. В ряде топонимических преданий одним из основных звучит мотив спора между тувинцами и монголами из-за территорий, пастбищных угодий, которые периодически происходили между кочевниками. Распространены сюжеты, повествующие о появлении названий местных гор — Улуг Хайыракан, Кыргыс-Тей, Кежеге и др.; об озерах — Төре-Хөл и Тере-Хөл.Устные рассказы, примеры которых приведены, ценны тем, что передают древние названия многих географических местностей, гор, рек, озер и родовых кочевий Юго-Восточной Тувы, но и природных объектов, находящихся в настоящее время на территории другого государства, где они возможно уже забыты или переименованы. Потому фиксация таких преданий важна не только как устная история отдельных родоплеменных групп тувинцев, но и как показатель тесных исторических контактов приграничных районов Тувы и Монголии.
Revisiting the Beneficial Effects of Estrogen on the Skin: A Comprehensive Review of the Literature and a Look to the Future
Authors: Svoboda Ryan M , Del Rosso James Q , Zeichner Joshua A , Draelos Zoe D
Published: September 2018

The process of aging is associated with anticipated cutaneous changes such as epidermal thinning, dehydration, loss of barrier function, and decreased extracellular matrix components. These physiologic changes translate to clinical findings such as atrophy, pigmentary changes, and wrinkling. Over the past century, the role of decreased circulating estrogens in the process of cutaneous aging has been elucidated. Estrogen replacement, both systemic and topical, has been shown to have positive effects on aging skin by promoting fibroblast proliferation and increasing collagen density. However, despite these positive effects on skin health and appearance, estrogens also display a wide-range of actions on various other systems. Even topical estrogen application can result in unwanted systemic effects. Research into alternative substances such as soft estrogens—synthetic, non-hormonal molecules that produce local, cutaneous estrogenic effects and are then metabolized to inactive compounds prior to being absorbed into the systemic circulation— suggests that estrogenic-like benefits on aging skin could be harnessed safely, while avoiding the potential pitfalls associated with estrogen use.
Oxybenzone and Sunscreens: A Critical Review of the Evidence and a Plan for Discussion with Patients
Authors: Mirsky Rachel S , Prado Giselle , Svoboda Ryan M , Rigel Darrell S
Published: September 2018

There has been recent extensive controversy concerning potential environmental and health hazards of oxybenzone (also known as benzophenone-3 and Eusolex 4360). Although there has been widespread related media attention, there is little definitive scientific research supporting the associated concerns. Given these controversies, it is critical that dermatologists have a clear understanding of the underlying issues related to oxybenzone in order to effectively counsel their patients. The purpose of this article is to provide dermatologists with a framework for presenting this issue to patients. Within, we address questions such as: 1) Is oxybenzone the reason for coral bleaching? 2) Is there data to suggest that oxybenzone is harmful to humans? 3) Why is oxybenzone used in the majority of US sunscreens? and 4) Are there other potential problems with oxybenzone restrictions that could lead to more skin cancer in the future? After a careful review of the evidence, we conclude that, in our opinion, there is little definitive scientific research supporting the associated concerns and that before this evidence exists, given the benefits of oxybenzone-containing sunscreens in skin cancer prevention, this ban is premature.  Banning an ingredient commonly used in most sunscreens may lead to confusion among consumers and have the untoward outcome of less sunscreen being used overall.
Multi-Center Randomized Clinical Study of The Effects of Natural Oils on Xerosis and Skin Barrier Properties
Authors: Vaughn Alexandra , Nguyen Mimi , Maarouf Melody , Van Skiver Melisa , Tran Khiem , Rybak Iryna , Sivamani Raja , Shi Vivian Yan
Published: September 2018

Objective: To compare the effect of natural oils and white petrolatum on skin barrier function in patients with xerosis.Design, Setting, and Participants: Randomized, open label, comparison pilot study (NCT03093597).Interventions: Participants were randomized to apply 1 of 4 moisturizers to assigned treatment areas twice daily for 2 weeks. Clinical dry skin score, stratum corneum hydration, and transepidermal water loss (TEWL) were assessed at baseline, 1 week, and 2 weeks.Results: Thirty-two participants completed the study. Neither TEWL nor hydration were statistically different among the moisturizers at each visit. All four moisturizers led to significant initial increase in TEWL at week 1 (p < 0.05) with an associated increase in hydration for coconut oil, jojoba oil, and white petrolatum. All four moisturizers led to significant increase in hydration by week 2 (p < 0.01). The preferred moisturizers were almond oil and coconut oil, which were most “liked” by 38% and 31% of the participants, respectively. The least preferred moisturizer was white petrolatum.  Conclusions: Almond oil, jojoba oil, and coconut oil significantly increased hydration after 2 weeks, and are as effective as white petrolatum as daily moisturizers for xerosis. The participants preferred natural oils to white petrolatum, implying that these moisturizer options may improve patient compliance.
The History of Cosmetic Nail Treatments, From Babylon to Beyoncé
Authors: Zambito Jeanette R
Published: September 2018

Not available.
A Review of Auto-Injector Pen Safety and Preventative Strategies
Authors: Rodriguez Eduardo Adrian , Arnold Morgan Leigh , Wilkerson Michael G
Published: September 2018

Reports of auto-injector pen injuries have increased over the past decade. However, the true incidence of these injuries is unknown. We present the case of an accidental digital self-injection by a dermatologist whilst he was trying to administer the medication to a patient presenting with anaphylaxis as an example of a typical auto-injector injury. Additionally, we discuss safety issues, commonly reported injuries of accidental self-injection, and review the safety guidelines for use of a common auto-injector pen. Finally, we explore common barriers to proper auto-injector handling and suggested preventative strategies in order to decrease injuries caused by auto-injectors.
Nab-paclitaxel/Gemcitabine Induced Acquired Ichthyosis
Authors: Lopez Adriana T , Shugar Joel , Lebwohl Mark
Published: September 2018

The ichthyoses are a diverse group of cutaneous disorders characterized by abnormalities in cornification. The majority of ichthyoses are inherited with childhood presentation and new onset ichthyosis in adulthood warrants further medical evaluation. Though most well recognized for its association with Hodgkin’s disease, acquired ichthyosis (AI) has been linked to a number of inflammatory, autoimmune, and endocrine processes. However, drug induced AI is exceedingly rare and remains a poorly understood entity. Here we report the case of man with who developed AI while receiving nab-paclitaxel plus gemcitabine for treatment of pancreatic adenocarcinoma and review the literature.
Resolution of Post-Surgical Hypergranulation Tissue with Topical Aluminum Chloride
Authors: Prado Giselle , Nichols Anna , Zaiac Martin
Published: September 2018

Hypergranulation is the extension of granulation tissue beyond the required amount to close a tissue defect. We report our experience using aluminum chloride to treat a series of two patients with hypergranulation tissue. Both patients had lengthy treatment courses after Mohs surgery with growth of hypergranulation tissue that resolved once aluminum chloride was placed on the wound. Aluminum chloride is a useful hemostatic agent frequently employed in dermatology. It is a readily available and low-cost option for management of hypergranulation after dermatologic procedures. Chronic wounds are a common treatment challenge for clinicians. Due to its affordability and availability, clinicians may consider topical aluminum chloride when managing post-surgical hypergranulation tissue.
Treatment of Pityriasis Rubra Pilaris with Adalimumab: A Case Report
Authors: Kaminetsky Joshua R , Feit Eric J , Ungar Jonathan P
Published: September 2018

Pityriasis Rubra Pilaris (PRP) is a rare inflammatory dermatosis of unknown etiology and variable presentation. Common clinical features include hyperkeratotic follicular papules, palmoplantar hyperkeratosis and well-demarcated red-orange scaly plaques interspersed with islands of unaffected skin. A limited body of anecdotal evidence predominantly supports the use of systemic retinoids and/or methotrexate in treating the disease. In a subset of these patients, there has been a documented role for biologic tumor necrosis factor (TNF) inhibitors, especially in patients who have failed retinoid or antimetabolite therapy. We present a case of a woman whose PRP responded favorably to adalimumab, highlighting the role of TNF inhibitors and the need for their continued exploration in the treatment of PRP.
Utilization of Palm Oil Fuel Ash and Eggshell Powder as Partial Cement Replacement - A Review
Authors: Jhatial Ashfaque Ahmed , Goh Wan Inn , Mohamad Noridah , Sohu Samiullah , Lakhiar Muhammad Tahir
Published: September 2018

The increase in population leads to increase in construction of houses and other buildings to accommodate these people. The extensive use of concrete for constructional purposes leads to release of Carbon Dioxide (CO2) gas into the atmosphere which adds to the already increased global warming. The increase in urbanization has also lead to increased generation of waste materials. These waste materials are by-products, which are disposed in landfills causing environmental and health issues. The utilization of agricultural wastes as cement substitute is a great alternative for reducing the use and production of cement, which contributes to 5% to 7% of global CO2 emissions alone. Palm Oil Fuel Ash (POFA) Eggshells are two major agricultural wastes, which are generated in abundance in Malaysia. This paper reviews the combined utilization of Eggshells Powder (ESP) and POFA as potential partial cement replacement material and development of bio-concrete, which may help in reducing the environmental issues that are caused by the agricultural by-products. They have been used successfully but individually in concrete. The pozzolanic activity triggered by POFA requires Calcium Hydroxide which cement provides to a limit. Eggshells when grinded into Eggshells Powder (ESP) are rich in calcium oxide and can provide the required calcium hydride and enhance the pozzolanic reaction.
DevOps Round-trip Engineering: Traceability from Dev to Ops and Back Again
Authors: Jiménez Miguel , Villegas Norha M. , Tamura Gabriel , Müller Hausi A.
Published: September 2018

DevOps engineers follow an iterative and incremental process to develop Deployment and Configuration (D&C) specifications. Such a process likely involves manual bug discovery, inspection, and modifications to the running environment. Failing to update the specifications appropriately leads to technical debt, including configuration drift, snowflake configuration, and erosion across environments. Despite the efforts that DevOps teams put into automating operation work, there is a lack of tools to support the development and maintenance of D&C specifications. In this paper, we propose TORNADO, a two-way Continuous Integration (CI) framework (i.e., Dev→Ops and Dev←Ops) that automatically updates D&C specifications when the corresponding system changes, enabling bi-directional traceability of the modifications. Panorama extends the concept of CI, integrating operations work into development by committing code corresponding to manual modifications. We evaluated Panorama by implementing a proof of concept using Terraform templates, OpenStack and CircleCI, demonstrating its feasibility and soundness.
Detecting Transportation Modes with low-power-consumption sensors using Recurrent Neural Network
Authors: Wang Hao , Luo Haiyong , Zhao Fang , Qin Yanjun , Zhao Zhongliang , Chen Yiqu
Published: September 2018

With the quick development of mobile Internet and the popularity of smartphones, smartphone-based transportation mode detection has become a hot topic, which is able to provide effective data support for urban planning and traffic management. Though the popular GPS based transportation mode detection method has achieved reasonable accuracy, this method consumes large power, thus limiting it to be used in smartphones. Here, we propose a novel transportation mode detection algorithm using the recurrent neural network. In order to identify transportation modes with low power consumption, this algorithm only uses four low-power-consumption sensors (namely accelerator, gyroscope, magnetometer, and barometer) which are embedded in the commodity smartphones. Furthermore, we exploited the good representative ability of Long Short-Term Memory (LSTM) and applied it to recognizing the transportation modes to achieve higher accuracy. To filter noises, a preprocessing is applied. After calculating features, we adopt the LSTM learning algorithm to train a model of transportation mode recognition and employ this model to predict transportation modes. Extensive experimental results indicate that our proposed approach outperforms the compared state-of-the-art transportation recognition methods with 96.9% accuracy to detect four transportation modes, namely buses, cars, subways, and trains.
Pengaruh penambahan konsentrasi tepung tapioka terhadap komposisi gizi dan evaluasi sensori nugget daging merah ikan Madidihang
Authors: Lekahena Vanessa Natalie Jane
Published: September 2018

Nugget ikan adalah olahan daging ikan yang digiling halus yang dicampur dengan bahan pengikat dan bumbu lainnya, kemudian dikukus dan dicetak sesuai bentuk yang diinginkan. Daging merah ikan adalah bagian daging yang biasanya dibuang dan kurang disukai karena berbau amis dan tengik. Pemanfaatan daging merah ikan madidihang menjadi nugget merupakan bentuk diversifikasi olahan. Proses pembuatan nugget membutuhkan bahan pengikat berupa tepung sehingga menghasilkan produk dengan mutu yang baik. Tujuan penelitian ini adalah untuk mengetahui pengaruh penambahan konsentrasi tepung tapioka terhadap komposisi gizi dan evaluasi sensori nugget daging merah ikan madidihang. Komposisi gizi nugget ikan menunjukkan bahwa makin besar penambahan konsentrasi tepung tapioka yang digunakan dalam pembuatan nugget ikan meningkatkan nilai kadar air (48.98-54.58%) dan karbohidrat (16.46-19.95%) tetapi menurunkan kadar protein (13.71-17.61%), abu (1.98-4.49%) dan lemak (9.78-12.46%), sementara evaluasi sensori menunjukkan bahwa penambahan konsentrasi tepung tapioka berpengaruh nyata terhadap atribut tekstur, warna, dan aroma, tetapi tidak berpengaruh terhadap atribut rasa nugget.
Pengawasan kapal perikanan yang beroperasi di perairan Maluku Utara
Authors: Naim Armain
Published: September 2018

Pengawasan terhadap kapal perikanan dilakukan di pelabuhan pangkalan maupun langsung dilakukan di laut, diharapkan mampu mencegah terjadinya pelanggaran atau kejahatan di bidang perikanan. Penelitian bertujuan untuk mendeskripsikan kegiatan pengawasan dan hasil operasi pengawasan yang telah dilakukan dalam kurun waktu 2012-1016. Penelitian dilaksanakan di Ternate dengan melakukan penelusuran dan pencatatan data yang tersedia di Satuan Pengawasan Sumberdaya Kelautan dan Perikanan Ternate, Dinas Kelautan dan Perikana Kota Ternate, Dinas Kelautan dan Perikanan Provinsi Maluku Utara, Direktorat PolAir Polda Maluku Utara, dan Lanal Ternate. Hasil penelitian menunjukkan bahwa jumlah kapal ikan yang beroperasi di perairan Maluku Utara masih didominasi kapal berukuran ≤ 10 GT. Hasil operasi pengawasan periode lima tahun terakhir telah memeriksa 282 unit kapal ikan. Kategori kapal adhock sebanyak 53 unit untuk kapal ikan Indonesia. Pelanggaran yang paling banyak dilakukan oleh kapal ikan Indonesia adalah pelanggaran daerah penangkapan ikan. Kapal ikan asing pada kategori adhock sebanyak 5 unit yang terdiri dari 1 unit kapal pada tahun 2014 dan 4 unit kapal ikan asing pada tahun 2016. Kategori kapal yang ditenggelamkan terjadi pada tahun 2016 sebanyak 4 unit kapal ikan asing. Jenis pelanggaran yang dilakukan ke empat kapal tersebut adalah tanpa memiliki izin, yaitu surat izin usaha penangkapan (SIUP) dan surat izin penangkapan ikan (SIPI). Pelanggaran tersebut dinyatakan sebagai kejahatan (illegal fishing). Adapun pelanggaran terhadap Undang-Undang no 31, tahun 2004, pasal 26 ayat 1, Jo pasal 92, dan Undang-Undang no 45, tahun 2009, pasal 27 ayat 2, Jo pasal 93 ayat 2.
Pengaruh Kedalaman Terhadap Kelangsungan Hidup (Survival Rate) Benih Tiram Mutiara (Pinctada maxima) Stadia Spat
Authors: Kota Raismin
Published: September 2018

Tiram mutiara banyak ditemukan di perairan Indonesia salah satunya adalah tiram mutiara jenis Pinctada maxima. Jenis ini dikenal mampu menghasilkan mutiara yang berukuran cukup besar di kelasnya. Penelitian ini bertujuan melihat pengaruh kedalaman yang berbeda terhadap kelangsungan hidup (Survival Rate) benih tiram mutiara (Pinctada maxima) dan mengetahui kedalaman terbaik untuk kelangsungan hidup benih tiram mutiara stadia spat. Hasil pengamatan menunjukkan bahwa kelangsungan hidup benih tiram mutiara stadia spat tertinggi terjadi pada perlakuan K2 (kedalaman 6 m) dengan kelangsungan hidup (SR) sebesar 96% dikuti K1 (kedalaman 2 m) 92%, dan terendah K4 (kedalaman 14 m) sebesar 79%. Berdasarkan hasil Analisa Sidik Ragam (ANASRA) menunjukkan bahwa kelangsungan hidup tiram mutiara stadia spat pada masing-masing perlakuan Tidak Berbeda Nyata (non signifikan) dimana F hitung < F tabel 5 % (3,80 < 4.07), Hal ini disebabkan juga karena kualitas perairan yang diukur berada pada kisaran toleransi yang disukai tiram mutiara. Hasil pengamatan kualitas air seperti suhu 26,8 oC 28,9 oC, pH 78, salinitas 3234 ppt serta kecepatan arus 2027 cm/detik.
The Reflection of Regency Gentleman in Pride and Prejudice and Emma by Jane Austen
Authors: Tamrin Andi Febriana
Published: September 2018

This study is aimed to present the nature of gentleman in the Regency era as reflected in the selected novels of Jane Austen, entitled Pride and Prejudice and Emma. The men who are categorized as gentleman are shifted over the years. In the time before Industrial Revolution, the term “gentleman” belongs to nobility class, gentry or to men who did not use their own hands to work. However, after the Victorian era, the “gentleman” covers several terms. These are the army, clergy, and even for the merchants. The social class and wealth are the prominent factors that cause the changing of this pattern. Nevertheless, Austen’s concept of gentleman in her two novels is referred mostly by the virtue and behavior.
[RETRACTED] A Discourse Analysis of German Fairy Tale “Rapunzel” Written by the Brothers Grimm
Authors: Syam Andi Tenrisanna
Published: September 2018

This article has been retracted due to double publication found at https://journal.unnes.ac.id/nju/index.php/LC/article/view/14943 Apologies are offered to readers of the journal that this was not detected during the submission process.
Comprehending Narrative Text: The Effectiveness of Cooperative Integrated Reading and Composition (CIRC)
Authors: Fariduddin Miftah , Parlindungan Firman
Published: September 2018

The aim of this study was to investigate whether there was significant difference on the students’ reading comprehension of narrative text between those who were taught through Cooperative Integrated Reading and Composition (CIRC) method and those who were not. Forty-nine students were selected as the sample and quasi-experimental, non-randomized pre-test and post-test design were employed. The analysis of covariance showed that the students who were taught by using CIRC method statistically outperformed those who were not on their reading comprehension of narrative text, (F (1, 48) = 13.56, p < .05). This result implies that CIRC is an effective method to teach reading comprehension, particularly on narrative text. Since this study only focused on narrative text, future researchers might be interested to seek the effect of CIRC on other text genres. Similar study though may be conducted with a randomized design of larger population.
The Influence of Socratic Questioning Technique and Students Critical Thinking toward Their Speaking Competence at SMA Negeri 11 Ambon
Authors: Saleky Andre Paulus
Published: September 2018

This study is aimed at 1) describing the students’ speaking competence and 2) students critical thinking skill; 3) finding out the positive and the significant difference in speaking competence between the students who were taught by using Socratic Questioning Technique (SQT) and those who were taught by using Information Gap Technique (IGT); 4) finding out the positive and the significant differences in students speaking competence between those who had high and low critical thinking; and 5) finding out the positive and significant interaction in students speaking competence between teaching techniques and the critical thinking skill. A quasi experiment method (pre-posttest non-equivalent control group design) through the 2 × 2 factorial designs used to represents an independent variable and a dependent variable with different level of thinking. The results showed that there were significantly differences in speaking ability between students who had high critical thinking and those who had low critical thinking. The value of R was 0.840 with interval correlation (0.80 – 1.00) meaning coefficient correlation was very strong and significant in linear regression or gained regression criteria in addition there was a positive and significant interaction in speaking competence between teaching techniques and critical thinking skill.
Mentor Texts: Models to Improve False Beginners’ Writing Skills
Authors: Herusatoto Hesthi
Published: September 2018

This research was to find out the effects of mentor texts on students’ ability to write a descriptive paragraph. Changes in the content and organization of their paragraphs were examined closely. As many as 35 students majoring in nursing who were enrolled in an English class participated in this research. In the class, the students learned to write a descriptive paragraph using some mentor texts which served to help them learn identifying and writing a topic sentence, supporting sentences, and a concluding sentence. The texts also provided them with models to make a paragraph have unity and coherence. The data were collected from the student’ paragraphs produced before and after the learning process and the paragraph they wrote in the delayed posttest. A survey was also distributed at the end of their English class to collect their responses on the use of mentor texts in their learning process. The findings of this research indicated that mentor texts indeed had positive effects on the students’ ability to write a descriptive paragraph. Their awareness to include a topic sentence, details, unity, a concluding sentence, and transition signals in their paragraph was found to significantly develop. In addition, mentor texts enhanced the students’ confidence, interest, and motivation in writing.
Deictic Expressions in Nasreddin's Selected Stories
Authors: Panggabean Waladdin
Published: September 2018

The research discusses deictic expressions or deixis in Nasreddin’s selected stories. The research method applied in the research is qualitative research while the theory that is used in the research is the theory of deixis by Yule that is used to analyze the deictic expressions in the story book. The researcher uses qualitative research because the data of this research are limited to the words or phrases having deictic expressions in the book of Nasreddin, A Man with Thousands Ideas. The aims of this research are to identify the type of deixis and explain the references that appear in the book. The result shows that there are three types of deixis that appear in the book. The analysis also shows that anaphoric and cataphoric references are found in the story book.
Artistas y decoradores en el Teatro Municipal de San Nicolás de los Arroyos a principios del siglo XX
Authors: Murace Giulia
Published: September 2018

In Argentina, by the end of the 19th century and the beginning of the 20th, several opera houses appeared, in both large cities and small urban centers. One example is the Teatro Muncipal in San Nicolás de los Arroyos, inaugurated on August 10, 1908. This paper analyzes the historical-artistic aspects of the theater and the imaginary it contributed to build in a provincial city at the beginnings of 1900. Some peculiarities of this theatre lead us to highlight alternative routes of artistic circulation, where Buenos Aires is not always the center and where local intermediaries have had preeminence; since a greater dialogue with the city of Rosario than with the nation’s capital was established.
Sinkop Berulang pada Perempuan Muda
Authors: Yuniadi Yoga
Published: September 2018

Sinkop adalah ketidakmampuan mempertahankan postur tubuh akibat hilangnya kesadaran sesaat. Sinkop pada usia muda sering dikaitkan dengan kegagalan refleks vasovagal. Sinkop umumnya benigna walaupun pada subset pasien tertentu sinkop dapat merupakan gejala suatu kejadian yang mengancam jiwa. Oleh karena itu rawat inap karna sinkop sering terjadi akibat kesuliatan untuk segera mengetahui kausa sinkop, kurangnya kriteria baku untuk diagnosis dan kekhawatiran terhadap kemungkinan suatu aritmia yang berbahaya.
Ratio of EPC and CEC as Endotel Dysfunction Predictor in High Risk Group with Farmingham Risk Score 10 Years Category
Authors: Nurwidyaningtyas Wiwit , Sargowo Djanggan , Agoes Achdiat , W Titin Andri , Satuman S
Published: September 2018

Research background. Circulating Endothelial Cells (CEC) is a reflection of endothelial damage or endothelial stress, increasing of CEC amount depend on endothelial mechanism, edothelial adhesivity damage and cellular apoptosis as a result of decreasing sitoskleleton function. If higher exposure affects the increasing of CEC amount,VEGF other growth factor mediators will be reflected as endothelial stress manifestation which roles in the increasing of re-population and Endothelial Progenitor Cells (EPC) differentiation. Endothelial Progenitor Cells is a mononuclear cell (a part of stem cell) that could change to be mature endothel and roles in re-edothelialisation and neovascularisation. This research aimed to investigate the ratio of EPC : CEC in risk group through Framingham Risk Score (FRS) 10 years approach as endothelial dysfunction predictor.Research method and result. There were 55 research subjects whom taken by FRS scoring and devided into some risk groups and two control groups. They were control group I (health) and control group II (sick). Base blood was taken to every each of them to analyze their EPC and CEC with Flowcytometry. EPC was analyzed by CD34 Per CP Santa Cruz SC-19621 and CD 133 FITC (fluorescein isothiocyanate) Bioss bs-0395R-FITCmarker.WhileCEC was analyzed CD45 FITC Biolegend 202205 dan CD 146 PE Biolegend 134704 marker. Result showed, there was significant ratio differences of EPC : CEC in those six groups which was proven by p-value 0.032< ? (0.05). The higher ratio was in high risk group (139.06).Conclusion. Research showed that EPC amount was increase related to the increasing of high risk level according to FRS 10 years, but its increasing did not followed by its ability to homing in injury area as role part in re-endothelialisation process. It found that EPC amount was higher in high risk group than in low risk group.
Mangosteen Pericarp Inhibits Nuclear Factor ?B (NF-?B) Activation and Reduces Expression of ICAM-1 in High Cholesterol Diet Rat
Authors: Hendarto H , Rohman Mohammad Saifur , Sargowo Djanggan
Published: September 2018

Background: Atherosclerosis is widely viewed as an inflammatory disease with hypercholesterolemia being a dominant underlying risk factor. This study aimed to determine the effect of mangosteen pericarp in inhibition of NF-?B activation and ICAM-1 expression in rat fed with high cholesterol.Methods and Results: Various doses of crude extract mangosteen pericarp were administered to the high fat diet wistar rats and the activity of NF-?B measured by immunohistochemistry to assess nuclear NF-?B expression and the ICAM-1 expression. The high fat diet resulted significant increased serum LDL levels. Increased nuclear NF- ?B activation and ICAM-1 expression were also observed in high fat diet rats in concurrence with increased serum LDL. The inhibitory effect on NF- ?B activity and ICAM-1 expression was observed when 400 mg of mangosteen pericarp crude extract was administered and even showed a higher inhibitory effect in 800 mg of mangosteen pericap treated rats. The 800 mg extract treatment resulted in decreased ICAM-1 expression similar to those of non high fat rats.Conclusion: The administration of 800 mg mangosteen pericarp crude extract significantly inhibited NF-?B activation and reversed the expression of ICAM -1 to the normal level in high cholesterol diet rats.
Of All Antioxidants, Would One Finally Be Used Clinically For Atherosclerotic Disease?
Authors: Adiarto Suko
Published: September 2018

Oxidation of LDL by oxygen free radicals results in unregulated uptake of modified LDL by macrophages in arterial wall. This is considered a key initiating factor for development and progression of atherosclerotic process. It is then logical to hypothesize that anti-oxidants, which can directly scavenge free radicals, can be useful in preventing atherosclerotic process. Initial support for this hypothesis accumulated rapidly from numerous in-vitro studies.
Selection of Balloon Mitral Valvuloplasty Candidate in Rheumatic Mitral Stenosis
Authors: Soesanto Amiliana M
Published: September 2018

Balloon Mitral Valvulotomy (BMV), sometimes also referred to as Percutaneous Transcatheter Mitral Commissurotomy (PTMC) is becoming a common treatment option for patients with mitral stenosis. Compared to surgical valvotomy, it has less procedural risk, shorter hospital stay and comparable outcome. However, that good result can only be achieved in selected good candidates. This article will give a highlight of some consideration to choose a good candidate for BMV mostly evaluated by echocardiography.
Risk Stratification of Short Term Sudden Death after Acute Coronary Syndrome
Authors: Endang Jusup , Suprobo Dewi H , Prakoso Radityo , Yuniadi Yoga , Siswanto Bambang B , Hersunarti Nani
Published: September 2018

Sudden cardiac death is the leading cause of cardiovascular mortality in acute coronary syndrome. Risk stratification scoring tools are available to better identify patients at risk after acute myocardial infarction. In addition plenty of factors and treatment modalities modulate the risk of sudden cardiac death.A case of in-hospital SCD in a young woman with acute anterior STEMI is presented as a trigger to the importance of risk stratification and treatment according to guidelines in preventing SCD.
Amiodarone and its Pulmonal Toxicity
Authors: Darisan Kemalasari Nas , Zaini Jamal , Yuniadi Yoga
Published: September 2018

Amiodarone is an antiarrhythmic agent commonly used to treat supraventricular and ventricular arrhythmias. The drug prevents the recurrence of life-threatening ventricular arrhythmias and produces a modest reduction of sudden deaths in high-risk patients. This drug is an iodine-containing compound that tends to accumulate in several organs, including the lungs. It has been associated with a variety of adverse events. Of these events, the most serious is amiodarone pulmonary toxicity. Although the incidence of this complication has decreased with the use of lower doses of amiodarone, it can occur with any dose. Because amiodarone is widely used, all clinicians should be vigilant of this possibility. Pulmonary toxicity usually manifests as an acute or subacute pneumonitis, typically with diffuse infiltrates on chest x-ray and high-resolution computed tomography. Other, more localized, forms of pulmonary toxicity may occur, including pleural disease, migratory infiltrates, and single or multiple nodules. With early detection, the prognosis is good. Most patients diagnosed promptly respond well to the withdrawal of amiodarone and the administration of corticosteroids, which are usually given for four to 12 months. It is important that physicians be familiar with amiodarone treatment guidelines and follow published recommendations for the monitoring of pulmonary as well as extrapulmonary adverse effects.
Giant Coronary Artery Aneurysms in Kawasaki Disease Detected by Multi Detector Computed Tomographic
Authors: Lilyasari Oktavia , Roebiono Poppy S , Prakoso Radityo , Rahajoe Anna Ulfah , Sakidjan Indriwanto , Harimurti Ganesja M
Published: September 2018

Kawasaki disease is an acute, self -limited vasculitis of unknown etiology that occurs predominantly in infants and young children. The major sequele of Kawasaki disease are related to the coronary arterial system. Cardiac imaging is a critical part in evaluation of all patients with suspected Kawasaki disease. Multi Detector CT (MDCT) provides a safe non-invasive approach to accurately delineate coronary artery anatomic structure. We report a case of a 6 years old boy with history of Kawasaki disease. Multi detector CT scan showed giant aneurysm at proximal LAD, proximal RCA and medium aneurysm at proximal LCX. Patient then treated with the anticoagulant therapy.
Opportunistic Screening for The Detection of Newly Diagnosed Diabetes Melitus
Authors: Paputungan Sri R , Adam Fabiola MS , Adam John MF
Published: September 2018

Background. It is estimated that 50% of the diabetic patients are undiagnosed.Opportunistic screening is one of the screening method, to detectnewly diagnosed diabetes mellitus. The aim of this study is to detect theundiagnosed diabetes mellitus by screening in the clinical setting.Subjects and Methods. Subjects were form the EIDEG screening fordiabetes mellitus. The procedure is a two step screening, first using thereflectance meter for capillary blood sugar, followed by confirmation testin the laboratory. Capillary blood sugar was divided into 3 groups, < 100mg/dL as normal, 100-199 mg/dl possible diabetes, and ? 200 mg/dL suspecteddiabetes. For group two, an OGTT was performed, and for groupthree, only FPG. Diabetes mellitus was diagnosed if FPG ? 126 mg/dl andor 2 hour OGTT ?200 mg/dl.Results. During the screening, 4737 subjects can be screened, only 1654completed the screening. Diabetes mellitus was diagnosed in 240 subjectsor 14.5%. There were more females compared to males, 52,9% and 47,1%subsequently, most were at the age ?50 years. More diabetic patients werediagnosed by OGTT compared to FPG only.Conclusions. This study showed that opportunistic screening may detectmore diabetic patients. It is suggested that this screening procedure canbe used by every clinicians in their daily practice.
Permanent Pacemaker Implantation Through Persistent Left Superior Vena Cava: Safe for Normal Heart Position and Dextrocardia
Authors: Maharani Erika , Yuniadi Yoga
Published: September 2018

Permanent pacemaker implantation in patient with persistent left superior vena cava (LSVC) has been reported in literature. Some authors has also been reported pacemaker implantation in patient with dextrocardia. Both of this situation has a challenging situation in placing the lead in right ventricle and risks of lead dislocation. We report two cases of successful pacemakers implantation,one with mirror image dextrocardia, in patient with persistent LSVC.
Torsades de Pointes pada pasien Hipokalemia: Peranan Afterdepolarization pada mekanisme Takiaritmia
Authors: Tondas Alexander , Yuniadi Yoga
Published: September 2018

KasusSeorang wanita usia 56 tahun, dengan riwayat gagaljantung dalam pengobatan dengan obat diuretik furosemid, mengalami muntaber selama 3 hari terakhir. Saat tiba di UGD, EKG dengan irama sinus tiba-tiba mengalami degenerasi menjadi takikardia QRS lebar polimorfik saat perekaman. Presentasi hemodinamik pasien menjadi tidak stabil sehingga diputuskan untuk dilakukan kardioversi elektrik. Setelah defibrilasi, irama jantung kembali menjadi irama sinus dan hasil laboratorium menujukkan hipokalemia berat (2,4 meq/L). Setelah koreksi potassium dan perawatan, pasien membaik kemudian dipulangkan. Apa mekanisme tercetusnya torsades de pointes pada pasien ini?
Diagnostik Angiografi dan Intervensi Non-Invasif pada Tetralogy of Fallot (Tof)
Authors: Prakoso Radityo , Prahasti Danayu Sanni
Published: September 2018

La Maladie Bleue yang dideskripsikan olehLouis Arthur Etienne Fallot pada tahun 1888,merupakan gambaran klinis dari fisiologiyang disebabkan malformasi anatomisPenyakit Jantung Bawaan (PJB) yang saat ini disebutdengan Tetralogy of Fallot (TOF).1 Gambaran utamakelainan ini terdiri dari hubungan interventrikularatau ventricular septal defect, hubungan biventrikulardari cabang aorta yang menaiki otot septum ventrikel,obstruksi aliran ventrikel kanan, dan hipertrofiventrikel kanan. Tiap komponen mempunyai derajatkeparahan yang bervariasi, dan mempengaruhimanifestasi klinis dan tatalaksana penyakit tersebut.1,2Perkembangan tatalaksana TOF dari paliatif menjadibedah korektif pada balita dan anak-anak diikuti denganberkembangnya peran intervensi transkateter.
Lead Removal of Cardiac Implantable Electronic Device
Authors: Antara I Made Putra Swi , Yuniadi Yoga
Published: September 2018

As more people are living longer with more significant cardiac disease,permanent pacemakers (PPMs) and implantable cardioverter-defibrillators(ICDs) are being inserted more frequently each year. Beginning early in the21st century, there has also been an expansion in the indications for cardiacimplantable electronic devices (CIED, a term which includes PPMs andICDs), and device therapy has become more complex, frequently involvingmultiple leads per patient. In turn, there will be more occasion where thelead removal for these CIED will be necessary.A 6 y.o. patient was incidentally found to have a fractured pacemaker leadduring during routine x-ray for his respiratory tract infection. The pacemakerwas inserted 5 years ago, indicated for the permanent total atrioventricularblock developed after total correction surgery in Tetralogy of Fallot. Thelead fracture was thought to be caused by a phenomenon known as thesubclavian crush syndrome. A transvenous lead extraction in this patientwas only partially successful, leading to a surgical removal of the remaininglead. A new permanent pacemaker along with a new lead in the apexwas successfully inserted before the surgery.There are different levels of recommendations on whether a lead shouldbe extracted or left behind. And in times where removal was needed,new specialized tool and techniques have developed in the last decade forthe safe and successful retrieval of implanted pacemaker leads.
Pedoman Tatalaksana Dislipidemia PERKI 2013
Authors: E Erwinanto , Santoso Anwar , Putranto Johannes NE , Tedjasukmana Pradana , Suryawan Rurus , Rifqi Sodiqur , Kasiman Sutomo
Published: September 2018

Pedoman tatalaksana ini merupakan pedomantatalaksana dislipidemia pertama yang dibuat olehPERKI. Tujuan pembuatan pedoman tatalaksana iniadalah untuk membantu dokter membuat keputusandalam praktek sehari-hari. Pedoman inimenyarikandan mengevaluasi bukti-bukti yang ada ketikapedoman tatalaksana ini dibuat. Isi dari pedomantatalaksana ini mengacu terutama pada pedomantatalaksana dislipidemia ESC/EAS tahun 2011 sertaberbagai hasil penelitian lainnya. Keputusan akhirtentang terapi individual merupakan tanggung jawabdari dokter yang menangani pasien.
Secretory Phospholipase A2 Tipe Ii (Spla Ii) pada Penyakit Kardiovaskuler
Authors: Sargowo Djanggan
Published: September 2018

Reaksi inflamasi berperan dalam beberapa pathogenesis kondisi kardiovaskuler seperti atherosklerosis dan kerusakan iskemikpada infark miokard akut (IMA). Di antara mediator-mediator yang terlibat dalam inflamasi tersebut adalah enzim secretoryphospholipase A2 tipe II (sPLA2-II). Meskipun beberapa sel memang memproduksi sPLA2-II, namun sintesis oleh sel-sel tertentuseperti hepatosit, adalah khas sebagai reaktan fase akut. Literatur terbaru menyatakan banyaknya peran dari sPLA2-II dalampenyakit kardiovaskuler. Dalam tulisan berikut, akan mendiskusikan peran sPLA2-II dalam berbagai model atherosklerosisatau IMA, baik in vitro maupun in vivo, termasuk perspektif terapeutik dari sPLA2-II inhibitor. Disimpulkan bahwa sPLA2-IImerupakan mediator inflamasi yang penting dalam penyakit kardiovaskuler.
MRI Kardiak untuk Gagal Jantung akibat Kardiomiopati
Authors: Wicaksono Sony Hilal , Syamsul Donny Setyawan , Primasari Citra , Gayatri Aprivita , Permana Asmoko Resta
Published: September 2018

Kardiomiopati (KM) merupakan penyakit miokardium dengan karakteristik gangguan yang nyata pada morfologi, elektrofisiologi dan fungsi jantung.1 Definisilain menyebutkan bahwa KM adalah kelainan miokardium dengan abnormalitas pada struktur dan fungsi otot jantung, tanpa adanya penyakit jantung koroner, hipertensi, penyakit jantung katup ataupun kongenital yang melatarbelakanginya.Kardiomiopati dapat diklasifikasikan dalam dua kelompok besar yaitu KM primer dan KM sekunder. KM primer merupakankardiomiopati yang etiologinyatidak diketahui sedangkan kardiomiopati sekunder merupakan kardiomiopati yang diketahui etiologinya atau terkait kelainan sistemik maupun kelainanmiokardium khusus lainnya.2 Penegakan diagnosis KM dan klasifikasinyadidasarkan pada penilaian morfologi dan fungsi jantung.3 Penetapan diagnosis KM primer dilakukan dengan mengeksklusi penyakit/kelainan jantung yanglain.4 Seiring pengamatan klinis, perbedaan antara KM primer dan sekunder akan menjadi semakin jelas, karena ditemukannya etiologi pada kasusyang sebelumnya dianggap merupakan kelainan idiopatik.2
Peran Fibrinogen dan hs-CRP sebagai biomarker pada Penyakit Jantung Koroner
Authors: Rachman Otte J
Published: September 2018

Sindroma Koreoner Akut (SKA) yang merupakan penyebab kematian utama dari Penyakit Jantung Koroner (PJK) adalah suatu sindroma yang kompleks dengan penyebab multiple, sehingga upaya pengobatan akan lebih efektif jika ditujukan pada penyebab yang mendasarinya. Penyebab utama SKA meliputi: (1) adanya rupture plak disertai trombosis akut, (2) obstruksi mekanik yang progresif, (3) inflamasi, (4) adanya angina tak stabil sekunder dan (5) adanya obstruksi yang dinamik (vaso-konstriksi).1 Masing-masing penyebab ini saling menyumbang dan memberikan gambaran klinis yang berbeda satu sama lain sesuai dengan variasi kombinasi penyebab. Keadaan itu mempengaruhi strategi pengobatan yang berbeda pula. Pemberian vasodilator seperti nitrat, obat penyekat kalsium amat berguna jika penyebab utamanya suatu vasokonstriksi dinamik. Pemberian statin yang berfungsi sebagai antiinflamasi mungkin dapat berguna pada penderita dengan komponen inflamasi yang dominan.
Left Atrial Myxoma in Pregnancy: A Challenge in Diagnosis and Management
Authors: Candrasatria, Rony Mario , Siswanto Bambang Budi , Hersunarti Nani , Soerarso Rarsari , Kuncoro BRM Ario S. , Soesanto Amiliana M.
Published: September 2018

Primary tumors of the heart are rare where myxomas predominate as the most common type of primary cardiac tumors in all age groups. Even rarer, the incidence of myxomas during pregnancy is reported extremely low in the medical literature. The hemodynamic changes during pregnancy play an important role in influencing the clinical manifestation. The management is vary, depending on the week of gestation and risk assessment for both the mother and baby.We report a case of left atrial myxoma in 33-34 weeks of pregnancy. After judicious consideration, the patient was planned to have caesarian section at the full term pregnancy that will be followed one week after by tumor resection.
Role of Radial Artery Varians on Transradial Procedure
Authors: Wangko Loretta C. , Budiono Bambang , Lefrandt Reggy L.
Published: September 2018

Nowadays, transradial approach has become the most chosen procedure by the intervention cardiologists, either in diagnostic or coronary intervention. Possibilities of vascular variants of the radial artery and along the vascular axis until the aortic arch are not a reasonable challenge for not using this transradial approach. Complications due to the transradial approach are very rare and mostly are easier to be managed than due to the other approaches. Besides that, eary ambulation, comfortability and satisfaction of the patients, and a relative low cost lead it to be the most preferable one. Data and publication of variants along the axis of the radial artery to the aortic arch are very supporting to the procedure success. A thorough understanding and consideration about the variants can diminish the failure of this transradial approach or the crossover to another approach.