bluuebunny/crossref_metadata_2025 huggingface dataset:
QUALITY OF WORK LIFE KARYAWAN KOPI AMPIRONO DAN IMPLIKASINYA TERHADAP WORK ENGAGEMENT
Authors: Fitriana Nita , A’yunina CH Qurrata
Published: April 2024

Kopi Ampirono’s employees decided to stay and work at Kopi Ampirono even the work’s demand is high and it has standard compensation. The aim of this study is to describe the quality of work life and its implication on work engagement at Kopi Ampirono. This research is descriptive qualitative research with phenomenology approach and explication technique as the analysis method.. Data collection used observation, document and interview with 10 informants of management and employees of Kopi Ampirono. The research result showed that: only one of four indicators of quality of work life is the main reason for the employees to stay and work at Kopi Ampirono. It is communication indicator. Quality of work life at Kopi Ampirono gives the implication on employee’s work engagement. Work environment and harmonic communication made the employees engaged and decided to stay and work at Kopi Ampirono. Only one of three indicators of work engagement had high engagement. It is vigor indicator
ERCP SONRASI PANKREATİT İLE PREOPERATİF DÖNEMDE BAKILAN LABORATUAR PARAMETRELERİNİN İLİŞKİSİ
Authors: Önem Soner , Dolu Süleyman , Camcı Mehmet , Yüksel Arif
Published: April 2024

Amaç: ERCP öncesinde bakılan laboratuar tetkikleri ile post-ERCP pankreatit ilişkisinin araştırılması

Araçlar ve Yöntem: İzmir Bozyaka Eğitim Araştırma Hastanesinde Mart 2015- Haziran 2016 tarihleri arasında yapılan ERCP işlemleri retrospektif olarak incelendi. ERCP yapılan hastaların yaşı, cinsiyeti, ERCP endikasyonları, ERCP sırasında yapılan işlemler, işlem sonrası oluşan komplikasyonlar belirlendi. Hastaların işlem öncesinde bulunan hastaların beyaz küre, nötrofil, lenfosit, hemoglobin, trombosit, INR, AST, ALT, ALP, GGT, total bilirubin, albumin, LDH değerleriyle post-ERCP pankreatit ilişkisi araştırıldı.

Bulgular: Hastaların işlem öncesi bakılan laboratuar parametrelerinden GGT ve AST seviyesi ise pankreatit geçiren hastalarda, geçirmeyenlere oranla düşüktü. (GGT p=0.001, AST p=0.006). Diğer parametrelerde ise anlamlı fark saptanılmadı.

Sonuç: Post-ERCP pankreatit ERCP’nin en sık görülen komplikasyonudur. Pankreatit gelişimi açısından risk faktörleri bulunan hastaların tespiti erken tanı ve tedavi açısından önem taşımaktadır. AST düzeyinin normal üst sınırından 1.5 kat ve GGT düzeyinin 4 kattan düşük olması pre-operatif pankreatit risk değerlendirmesinde kullanılabilir.
Pharmacophore-based virtual screening of bioactive peptides as dipeptidyl peptidase 4 inhibitor for type 2 diabetes mellitus drug candidates
Authors: Muttaqin Fauzan Zein , Rhamadianto Muhamad Iqbal , Jafar Garnadi , Ruswanto  , Patonah
Published: April 2024

Background: Diabetes is a chronic disease characterised by high blood sugar levels. Glucose that accumulates in the blood without being properly absorbed by the body's cells can cause various organ problems. If diabetes is not properly controlled, various complications can occur that endanger the life of the affected person.   
Objective: To find bioactive peptides that have the potential to inhibit di-peptidyl peptidase 4 (DPP-4) enzyme as anti-diabetes drug candidates.    
Method: This research was carried out using pharmacophore-based virtual screening.   
Result:  The validation of the pharmacophore-based virtual screening method showed that model III, which had five pharmacophore features consisting of three Pi interactions, one hydrogen bond donor, and three hydrogen acceptors, was the best pharmacophore model with the values of AUC 0.59; EF 1.2; Se 0.69; Sp 0.94; ACC 0.84; Ya 0.06; and GH 0.2. The screening of the 168,400 short-chain peptides using validated pharmacophore model III gave 51 tetrapeptides as the hits compounds with a pharmacophore fit score of more than 50.0%.   
Conclusion: In total, 51 tetrapeptides were enlisted as potential as anti-diabetes mellitus drug candidates.
Molecular docking studies of novel s-triazine derivatives incorporating amino methoxy chalcone for EGFR inhibitor in breast cancer
Authors: Dona Rahma , Rizki Rahmi Asrina , Jasril  , Frimayanti Neni , Hendra Rudi
Published: April 2024

Background: The Epidermal growth factor receptor (EGFR) receptor is involved in both apoptosis and angiogenesis. An upregulation of EGFR activity can potentially expedite the proliferation of malignant cells. Anticancer activity is among the many pharmacological activities of s-triazine derivative compounds. The potential of amino chalcone derivatives as anticancer agents has been documented. The anticipated outcome is that the derivatives of these two compounds will enhance their efficacy as antiproliferative agents.
Objective: Through molecular docking, this study aimed to assess the potential of eight novel trichlorotriazin compounds derived from amino chalcone as EGFR inhibitors in breast cancer.
Method: The molecular docking process was carried out with the assistance of the software package identified as the molecular docking environment (MOE) 2023.0901.
Results: Compounds two and four, which have a similar binding orientation to the positive control, have the potential to inhibit EGFR, according to molecular docking results. For developing new s-triazine derivatives that are potent agents against breast cancer, the molecular docking outcomes of compounds two and four may require additional consideration.
Conclusion: Compounds which are two and four have surfaced as noteworthy contenders.
Adherence of HIV/AIDS patients to clinical outcome in Semarang City
Authors: Sabiti Farroh Bintang , Arief Thendi Abdul , Sofa Nada Aini , Saputra Rendi Adi , Aryani Iga Citra , Nastiti Nindita Sari , Faizatun Arvin
Published: April 2024

Background: The success of HIV therapy can be measured by clinical, immunological, and virological monitoring. Meanwhile, low adherence to antiretroviral therapy (ART) contributes significantly to the disease progression and emergence of drug-resistant HIV.
Objective: This study aimed to determine the correlation between the adherence of HIV/AIDS patients to clinical outcomes in Semarang.
Method: This was an observational and cross-sectional approach. The instrument used the Simple Medication Adherence Questionnaire (SMAQ), which was validated and distributed to 50 respondents. The data were analyzed using chi-square (p < 0.05), and the results showed a statistically significant relationship.
Result:  Respondents were male (96%), aged 26-45 years (76%), high school graduates (24%), working (88%), single (86%), without comorbidity (86%), length of treatment more than 12 months (80%), and general treatment (50%). A total of 31 respondents (62%) adhered to treatment with the combination regimen of Tenofovir/Lamivudine/Efavirenz (20%). There was a significant relationship (p = 0.006) between the length of treatment and patient adherence. The adherence results were not significantly related (p > 0.05) to virological outcomes.
Conclusion: There is no significant relationship between the adherence of HIV/AIDS patients and clinical outcomes.
Development of nanoliposome formulation of beta-carotene using high speed homogeniser method
Authors: Chabib Lutfi , Ar Rodli Fakhrul Hakim , Nugroho Bambang Hernawan , Suryani Arman , Firmansyah Ferdy
Published: April 2024

Background: Beta carotene has hydrophobic and unstable properties. Nanoliposomes can package various types of drugs, including hydrophilic and hydrophobic drugs, as well as biological substances such as DNA, RNA, and proteins. This allows for more efficient and targeted drug delivery, making it possible to formulate beta-carotene nanoliposomes to improve efficacy and stability.
Objective: To formulate and characterise betacarotene liposomes using high speed homogeniser method and to conduct an accelerated stability test on betacarotene liposomes produced using high speed homogeniser method.
Methods: Nanoliposomes were prepared by high speed homogeniser method with time variation of 3, 6, 9 and 12 minutes and characterised for particle size, zeta potential value, polydispersity index, encapsulation efficiency, and stability.
Results: The preparation of nanoliposomes produced a yellow, odourless suspension with antioxidant activity, with particle size characteristics measuring 200-300 nm, with a polydispersity index of 0.2-0.5 and potential zeta values ranging from -25 mV to -30 mV, encapsulation efficiency value of 97% and morphology of liposome particles in the form of spherical globules with 500x magnification.
Conclusion: Formulation with a time variation of 12 minutes has recommended characteristics with spherical shape having good particle size, polydispersity index value, zeta potential value and encapsulation efficiency value.
Formulation and effectiveness of solid soap preparations from citronella grass (Cymbopogon nardus L.) essential oil extract against Listeria monocytogenes
Authors: Jayadi Lukky , Kesuma Sandry , Wattiheluw Muhammad Hasan , Widayanti Elok , Sabila Nurma , Widwiastuti Hanandayu , Asworo Riska Yudhistia , Ikayanti Retno
Published: April 2024

Background: The components of essential oils, such as citronellol, citronellal, and geraniol have been reported to possess the ability to inhibit bacteria. Furthermore, Listeria monocytogenes is a bacteria that often affects humans and its infections can cause meningitis and bacteremia. In pregnant women, Listeria monocytogenes can cause flu-like syndrome with complications of miscarriage, infant death, and meningitis in infants.    
Objective: This study evaluated the suitability of solid soap preparations from Citronella grass essential oil, based on its physical properties, such as organoleptic tests, as well as assessments of chemical tests and the effectiveness of the sample produced against bacteria.    
Method: The soap-making process was initiated by mixing the fat fraction (stearic acid and coconut oil) with an alkali, namely 30% NaOH. The soap stock was then added to the other ingredients and stirred until it became homogeneous for testing.    
Results: The test showed a pH value, water content, total fat, ethanol insoluble material, free fatty acids, chloride content, and unsaponificable fat of 10.8, 14.26, 74.84, 2.4, 0.26, 0.48, and 85.8, respectively. Furthermore, the sample showed a high level of inhibition against Listeria monocytogenes.    
Conclusion: Evaluation of citronella essential oil extract soap met the requirements, except for its unsaponifiable fat.
Analysis of total flavonoid and antioxidant activity of coconut shell liquid smoke (Cocos nucifera L.) as an antibacterial
Authors: Masfria  , Syahputra Hafid , Wahyuni Henny Sri , Zebua Nilsya Febrika , Elizabeth  , Marcelynn
Published: April 2024

Background: Coconut shell is often used for cooking or treated as waste. Liquid smoke is a by-product of coconut shell processing, which results from condensation of combustion steam. It is divided into grades one, two, and three based on the characteristics and utilisation. It contains phenolic, carbonyl acids and other compounds which act as antioxidants, antibacterials, and antifungals.
Objective: To determine the total content of flavonoids, antioxidants and antibacterial activity in liquid smoke.    
Method: Liquid smoke was produced by a pyrolysator and distilled to produce grades one, two and three. It was then tested for antibacterial activity using the minimal inhibitory concentration (MIC) method against S. aureus and E. coli. The AlCl3 reagent and DPPH method were used to determine the total flavonoid and antioxidant levels, respectively.     
Results: The MIC of grade one, two, and three coconut shell liquid smoke was 10%; 10%; 5% against S. aureus; and 10%, 5%, and 5% against E. coli. The total flavonoid yields from grades one, two and three were 0.0041, 0.0174, and 0.2741 mg QE/ml, respectively. Test results for antioxidant grades with IC50 values were 142.82, 121.64, and 90.80 µg/mL.     
Conclusion: Coconut shell liquid smoke has antibacterial activity, contains a certain amount of flavonoids, and also possesses antioxidant activity.
The implementation of the CDS-quiz, a novel educational method, in augmenting the knowledge and competence of pharmaceutical technical personnel
Authors: Widyaningrum Naniek , Sofa Nada Aini , Winarsih Serina Salmathifa , Oktasari Masita
Published: April 2024

Background: Pharmaceutical personnel are crucial to therapy implementation within healthcare facilities. The predicament lies in optimising the role of pharmaceutical technical staff within clinical pharmacy services, acting as a support system for pharmacists. The impediment to achieving higher satisfaction is attributable to pharmaceutical personnel's inadequate knowledge and skills. Therefore, a need arises for an efficient educational method to enhance their knowledge and proficiency.    
Objective: To examine the implementation of the CDS-Quiz for enhancing patient knowledge and satisfaction.    
Method: Over 90 day-research was conducted employing ceramah-, discussion-, and skill-quiz (CDS-Quiz). The respondents consisted of ten PTPs in healthcare facilities. The assessment of patient contentment was undertaken before and following the intervention.     
Result: After implementing the CDS-Quiz, there was a statistically significant enhancement in PTPs’ knowledge and proficiency (p < 0.001). These include a substantial upswing in patient contentment levels concerning reliability (68.8% to 89.6%), responsiveness (71.1% to 88.8%), and empathy (81.2% to 92.6%) in the provision of pharmaceutical services within the healthcare facility. There was also an increase in assurance (88.2% to 95.5%) and tangible (86% to 91.7%).    
Conclusion: The CDS-Quiz method proved the enhancement of the knowledge and skills of PTPs in healthcare services and can be applied to maximise pharmaceutical services.
Development rat models of nephrotoxic: A pre-clinical test model to discover nephroprotective agents
Authors: Sandhiutami Ni Made Dwi , Desmiaty Yesi , Fahleni  , Noviani Yuslia
Published: April 2024

Background: The use of drugs, including aminoglycoside drugs and anticancer drugs, is one of the things that can cause toxicity to the kidneys. Therefore, the development of agents that function as nephroprotectors continues to be researched.
Objective: This study aims to obtain a nephrotoxic experimental animal model for testing nephroprotective agents.
Method: The treatment was normal group, groups given a single dose of Cisplatin 7 mg/kgBW i.p (Cis), Doxorubicin single dose 25 mg/kgBW i.p (Dox-25), Doxorubicin repeated dose 4 mg/kgBW i.p twice/week for two weeks (Dox-4 repeated dose), and Gentamicin single dose 112 mg/kgBW i.p (Gen). The nephrotoxic effect was assessed by the parameters of kidney weight ratio, Ureum, Creatinine and Albumin levels in rat serum.
Result: The nephrotoxic effect was indicated by an increase in the renal weight ratio of the Cisplatin; Dox-25, Dox-4 repeated, and Gen groups than normal, respectively. There was an increase in serum BUN levels, an increase in serum creatinine, and a decrease in serum albumin levels compared to the normal group.
Conclusion: Cisplatin, Doxorubicin and Gentamicin have nephrotoxic effects. The administration of a single dose of cisplatin at 7 mg/kg BW gave the strongest nephrotoxic effect, making it appropriate as a model of acute nephrotoxicity in rats.
Synthesis, and molecular docking of thiourea derivatives as antibacterial agents targeting enzymes involved in biosynthesis of bacterial cell wall
Authors: Suzana  , Diyah Nuzul Wahyuning , Susanti Rini , Najati Fika Amalia , Ekowati Juni , Budiati Tutuk
Published: April 2024

Background: New antibacterials are needed due to the increasing resistance of bacteria to existing antibiotics. Thiourea derivative compounds (benzoylthiourea and 1,3-dibenzoylthiourea) contain aromatic groups, thio groups (C=S), and amide groups (H2N-C=O), which are commonly found in the class of antibacterial drugs. Molecular docking can be used to predict their antibacterial activity.    
Objective: This study aimed to synthesise thiourea derivatives and predict their antibacterial activity by in silico method.    
Methods: Synthesis was performed using nucleophilic substitution reactions. The synthesised compounds were identified using UV-Vis, FT-IR, and 1H-NMR. Molecular docking was conducted using the MOE program ver 2022.02.   
Results: Benzoylthiourea (BTU) and 1,3-dibenzoylthiourea (DBTU) compounds were obtained with yields of 36.55% and 12.68%, respectively. The melting point 171-173°C for BTU and 202-204°C for DBTU. Molecular docking results showed higher binding affinity of DBTU against PBP2a (docking score < -5.75 kcal/mol) and FaBH (docking score <-4.7935 kcal/mol) compared to the corresponding native ligands, while the two compounds had lower affinity for the muramyl ligase.    
Conclusion: BTU and DBTU can be synthesised by nucleophilic substitution reactions. DBTU is predicted to exhibit antibacterial activity against Methicilin Resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis.
Advancing Structural Understanding: System Identification of Steel Plate Girder Bridges in Nepal
Authors: Joshi Gangesh Kumar , Yadav Raghabendra , Arayal Sushma
Published: April 2024

Efficient infrastructure management relies on accurate bridge system identification, crucial for societal well-being and economic prosperity. This research pioneers a method to determine the fundamental frequency of steel plate girder bridges using smartphone accelerometers and Finite Element Method (FEM) modelling. Conducted along the East-West Highway in Nepal, this study focuses on 12 motorable bridges, employing the Android app Phyphox to gather vibration data induced by highway traffic. By applying operational modal analysis and peak picking techniques, the natural frequencies of these bridges are pinpointed, while a detailed FEM model in SAP2000 aids in correlating field observations. Notably, the study reveals that a bridge's span significantly influences its frequency, with longer spans exhibiting lower frequencies and vice versa. Close alignment between FEM predictions and smartphone-acquired data underscores the method's reliability, with disparities generally limited to 10%, primarily attributed to simplifications in modelling assumptions. Moreover, the investigation identifies structural issues like girder cracks on Pasaha Bridge, elucidating instances where field observations diverge from FEM predictions. This comprehensive approach not only enhances our understanding of bridge dynamics but also furnishes invaluable insights for maintenance and infrastructure planning, essential for ensuring the longevity and safety of critical transportation networks.
Guías de Práctica Clínica de Artritis Reumatoide PANLAR, una apuesta pensada para todos
Authors: Fajardo Estefanía
Published: April 2024

Después de 15 años, PANLAR actualizará las guías de Artritis Reumatoidea (AR) con el objetivo de abordar las particularidades de los sistemas de salud y el manejo de la enfermedad en los países miembros. Además, espera que sean amigables para diversos públicos estratégicos.
Diretrizes de Prática Clínica para Artrite Reumatoide da PANLAR: Uma Abordagem Abrangente para Todos
Authors: Fajardo Estefanía
Published: April 2024

Após 15 anos, a PANLAR atualizará as diretrizes para Artrite Reumatoide (AR) visando abordar as especificidades dos sistemas de saúde e o manejo da doença nos países membros. Além disso, espera que sejam amigáveis para diversos públicos estratégicos.
Global Rheumatology torna-se a revista oficial da PANLAR
Authors: Fajardo Estefanía
Published: April 2024

Enquadrada na divulgação científica em Reumatologia, a GR terá uma participação especial na PANLAR 2024 com um workshop narrativo. O compromisso da revista em manter e fortalecer os padrões de qualidade e excelência na disseminação do conhecimento científico permanece.
Patient-Centered Medicine Takes Center Stage at PANLAR 2024
Authors: Fajardo Estefanía
Published: April 2024

This year, in addition to the VII Pan American Congress of Patients with Rheumatic Diseases, patients will have an active role in the development of PANLAR 2024 Congress within the scientific program and community activities.
Global Rheumatology becomes the official journal of PANLAR
Authors: Fajardo Estefanía
Published: April 2024

Framed within the scientific dissemination in Rheumatology, GR will have a special participation in PANLAR 2024 with a narrative workshop. The commitment of the journal to maintain and strengthen standards of quality and excellence in the dissemination of scientific knowledge remains.
Eski Mezopotamya ve Anadolu da Mutfak Kültürü
Authors: Soğandereli Fatma
Published: April 2024

nsanoğlunun yaşamını idame ettirmesindeki ihtiyaçlar hiyerarşisinde ilk sırada gelen beslenme, insanlığın yaşamına, faaliyetlerine, aktivitelerine yön veren bir olgudur. İnsanlık ilk başlardan itibaren doğadaki kaynakları kullanarak karnını doyurmanın bir yolunu bulmuştur. Daha sonralarında ise gelişen teknikler ve yerleşik hayata geçişle birlikte kentleşme zamanlarında kendi yiyeceklerini ekip, yetiştirip, hasat etmiş ve tüketmeye başlamışlardır. Her toplum; yaşam bölgesine, yiyecek ve içecek kaynaklarına göre kendi sofralarını sunmuş ve mutfak kültürü olarak yansıtmıştır. Tahıl, et ve sebzeleri değişik baharatlar ve soslarla çeşitlendiren Mezopotamya ve Anadolu toplumları, pişirme yöntemlerine de kendi yorumlarını katmışlardır. Mutfak kültürü bir bakıma da tarihsel süreçte dinsel ve toplumsal bir kimlik haline gelmiştir.
Electromagnetic Fields (Including Microwaves) Can Lower the Immune Response and Even Change The DNA
Authors: Maria Kuman
Published: April 2024

This article was written to draw attention to the experimentally found facts that external
electromagnetic fields (like microwaves) can not only lower the immune response; it can even change the type of species. This is possible because beside the material body, we have biofield - weak electromagnetic field seen as aura. My lifelong studies of the biofield (aura) found that it is weak Nonlinear Electromagnetic Field (NEMF), which we can expect to be sensitive to external electromagnetic fields with wide range of frequencies, including microwaves. The Chinese scientist Dr. Kanchen found experimentally in 1961 in China that microwaves with frequency 11 GHz change the type of species. This article is a serious warning that the new microwave technologies (used in our fast internet, cellular phones and TV) when shifting to higher and higher frequencies for faster and faster internet will reach the frequency 11 GHz,
which will change our DNA, turning us to a different type of species. Unfortunately, in the US we developed these technologies without studding their effect on humans. For that reason, in the US we don’t have any regulations about what should be the maximally allowed safe intensity and frequency of the fields used in these technologies (we have regulations only for ionization radiation). We need to correct this as soon as possible.
A NEW APPROACH TO HYPERBOLIC SPINOR B-DARBOUX EQUATIONS
Authors: ÜNAL DOĞAN , ÜNLÜTÜRK YASİN
Published: April 2024

In this research, spinor descriptions of the curves in surfaces have been given according to the B-Darboux frame in Lorentzian 3-space E_1^3. The relations between B-Darboux and Darboux frames have been specified via their spinor conceptions which expressed in both timelike and spacelike surfaces, separately. Additionally, all these spinor representations have been portrayed in the view of the B-Darboux frame (via the curvatures) in Lorentzian 3-space. The findings are supported by some theorems and corollaries.
THE PAUL-PAINLEVÉ APPROACH OF THE BLACK SCHOLES MODEL AND ITS EXACT AND NUMERICAL SOLUTIONS
Authors: ZAHRAN EMAD H.M. , BEKİR AHMET
Published: April 2024

In this article, we employ the Black Scholes model which plays a vital role in economic operation and financial market management. The Paul-Painlevé approach is used for the first time to achieve the exact wave solution to this equation. Furthermore, the numerical solution to this equation has been constructed by using the variational iteration method.
OPTICAL ART OF A PLANAR IDEMPOTENT DIVISOR GRAPH OF COMMUTATIVE RING
Authors: AUTHMAN MOHAMMED N. , MOHAMMAD HUSAM Q. , SHUKER NAZAR H.
Published: April 2024

The idempotent divisor graph of a commutative ring R is a graph with a vertex set in R* = R-{0}, where any distinct vertices x and y are adjacent if and only if x.y = e, for some non-unit idempotent element e^2 = e ∈ R, and is denoted by Л(R). Our goal in this work is to transform the planar idempotent divisor graph after coloring its regions into optical art by depending on the reflection of vertices, edges, and planes on the x or y-axes. That is, we achieve Op art solely through pure mathematics in this paper.
THE TRANSFORMATION OF THE EVOLUTE CURVES USING LIFTS ON R^3 TO TANGENT SPACE TR^3
Authors: ÇAYIR HAŞİM , ŞENYURT SÜLEYMAN
Published: April 2024

In this paper, firstly, we define the evolute curve of any curve concerning the vertical, complete, and horizontal lifts on space R^3 to its tangent space TR^3=R^6. Secondly, we examine the Frenet-Serret apparatus {T^* (s),N^* (s),B^* (s),κ^*,τ^* } and the Darboux vector W^* of the evolute curve α^* according to the vertical, complete and horizontal lifts on TR^3 by depend on the lifting of Frenet-Serret aparatus {T(s),N(s),B(s),κ,τ} of the first curve α on space R^3. In addition, we include all special cases the curvature κ^* (s) and torsion τ^* (s) of the Frenet-Serret aparatus {T^* (s),N^* (s),B^* (s),κ^*,τ^* } of the evolute curve α^* with respect concerning complete and horizontal lifts on space R^3 to its tangent space TR^3. As a result of this transformation on space R^3 to its tangent space TR^3, we could have some information about the features of the volute curve of any curve on space TR^3 by looking at the characteristics of the first curve α. Moreover, we get the transformation of the evolute curves using bifts on R^3 to tangent space TR^3. Finally, some examples are given for each curve transformation to validate our theoretical claims.
Milestones for Establishing Effective Research Activity and Education in Health and Social Care Organization
Authors: Ahmed Hafez , Ibrahim Nagwa
Published: April 2024

The development and sustained improvement of research activity is an essential pre-requisite for the progress of academic organizations. It is also a key element for career development of graduates and for attracting quality academic and clinical staff. Accreditation and similar quality assessment programs assign a heavy weighting for research activity and programs designed for its development. A good plan for the development and maintaining momentum for research activities is always met by challenges in most organizations, that could be classified under time management, financial barriers, expertise availability and lacking the appropriate direction. In this article, major obstacles will be presented and a rational approach presented, as a general guide, as to how research process could be developed and maintained in an academic organization that is relatively novice for research activity.
Criminal Provisions For Perpetrators Who Commit Criminal Acts of Copulation And Lewd Acts Against Minors
Authors: Diana Diana , Prawesthi Wahyu , Amiq Bahrul
Published: April 2024

The frequency of these crimes, one of which is the unlawful act of sexual abuse, which encompasses both fornication and copulation, demonstrates the current high rate of crimes against children. Children and the future of the nation are seriously and dangerously at stake from this. Sexual activity is a crime that seriously damages society, it is taken very seriously, and it makes people feel uneasy since it incites a dread of crime. Data collection, processing, presentation, and analysis related to an event constitute the process of research. to acquire a study outcome that is responsible for science. Normative juridical research is the kind that is employed. Articles 81 and 82 of Law Number 35 of 2014 concerning Amendments to Law Number 23 of 2002 concerning Child Protection discuss the legal provisions for child molestation against children.
Kajian Stabilitas Keuangan Bank Syariah: Pendekatan Literature Review
Authors: Ananta Gita Trizky , Wiranatakusuma Dimas Bagus , Aru Yazak , Yudiyanto Arif , Dewi Nuur Aini Puspita
Published: April 2024

Penelitian ini bertujuan untuk menganalisis karakteristik bibliometrik terkait bank syariah dengan menggunakan basis data Scopus dari tahun 2019 hingga 2023. Selain itu, penelitian ini memberikan rekomendasi terkait subjek potensial yang dapat menjadi fokus penelitian dan pengembangan lebih lanjut di masa mendatang. Melalui analisis bibliometrik terhadap 35 artikel menggunakan perangkat lunak VOSviewer, penelitian ini memungkinkan visualisasi pola, termasuk koinstalasi kata kunci. Temuan penelitian menunjukkan bahwa studi mengenai Bank Syariah masih terbatas dibandingkan dengan topik lain seperti bank Islam secara umum. Oleh karena itu, salah satu solusi yang diusulkan adalah mengembangkan jurnal khusus yang secara khusus memfokuskan pada Bank Syariah. Beberapa topik yang diidentifikasi dalam kata kunci dapat dijadikan referensi untuk penelitian mendatang, termasuk keberlanjutan peran bank syariah, stabilitas keuangan, prinsip syariah, dan kebijakan perbankan. Selain itu, penelitian ini memberikan penekanan khusus pada literatur yang mencakup Bank Syariah dalam konteks Indonesia, serta menyoroti topik potensial yang dapat menjadi fokus pembahasan dalam penelitian mendatang. Ini membuka peluang untuk penelitian lebih lanjut yang mendalam dan beragam dalam kerangka pengembangan perbankan syariah, terutama di Indonesia.
Determinan Minat Kunjung Kembali Wisata Halal Dengan Satisfaction Sebagai Variabel Intervening (Studi Kasus : Wisata Danau Lut Tawar Aceh Tengah)
Authors: Lathifah Aini
Published: April 2024

The purpose of this research is focussed on Lake Lut Tawar tourist destinations in Central Aceh regency, especially in evaluating factors that have the potential to affect the desire of tourists to return to destination Lake Lut Tawar after experiencing a decrease in visit during the Covid-19 pandemic in 2020-2022.   This research is categorized as quantitative research because it adopts the paradigm of positivism, which tests a particular population and sample by collecting accurate numerical data from the population. Based on the results of the statistical test of this study of 273 participants who visited the Tourist Destination Lake Lut Tawar in Central Aceh, it was concluded that the quality of services and tourist attractions have no influence on the interests of visitors. But quality of service, touristic attractions, destination Image, facilities, each have a positive and significant impact on visitors' interests through satisfaction. The findings also suggest that the influence of these factors on visiting interests can be influenced by the demographics of respondents, with a majority of Generation Z and residing in the area of Lake Lut Tawar, Central Aceh.
Collaborative Governance in Management of the JakLingko Program (Case Study on Public Transportation Management in DKI Jakarta)
Authors: Rahma Hanifa Aulia , Rosyadi Slamet , Gunarto Guntur , Simin
Published: April 2024

High population density and mobility in Jakarta have triggered persistent traffic congestion. The impacts are not only on time and cost but also on deteriorating air quality. Government efforts to provide alternative public transportation have not been fully effective, due to low public interest caused by inadequate facilities and limited accessibility. The solution is evident in the JakLingko Program, an initiative that integrates the public transportation system. To ensure the success of this program, the Jakarta Transportation Agency collaborates with public transportation modes and relevant businesses. Through this synergy, it is expected that public interest in using public transportation will increase, reducing the use of private vehicles, thereby alleviating traffic congestion and improving air quality in Jakarta. This research employs the collaborative governance model proposed by Ansell and Gash, encompassing four dimensions: initial conditions, institutional design, facilitative leadership, and collaboration processes. The research methodology is qualitative-descriptive. The research results indicate that collaborative governance in managing the JakLingko Program in Jakarta is fairly optimal, but not yet fully so.
Sistem Keamanan dan Kerahasiaan Rekam Medis di Rumah Sakit Umum Daerah Pasar Minggu Tahun 2023
Authors: Daeli Joverius , Ramadhani Malihah , Hartono Risky Kusuma
Published: April 2024

Untuk melindungi rekam medis pasien, ruang yang memenuhi kriteria keamanan dan kerahasiaan harus ditetapkan untuk penyimpanan rekam medis. Ruang penyimpanan rekam medis dapat dikatakan baik jika dapat mencegah bahaya yang dapat menimpa dokumen rekam medis, seperti kehilangan, kerusakan, atau bencana. Tujuan penelitian untuk mengetahui sistem keamanan dan kerahasiaan rekam medis di Rumah Sakit Umum Daerah Pasar Minggu. Dengan menggunakan desain penelitian observasional dan pendekatan kualitatif, penelitian deskriptif adalah metodologi penelitian yang digunakan. Instrument yang digunakan dalam penelitian ini menggunakan wawancara, observasi dan telaah dokumen. Hasil penelitian untuk keamanan rekam medis adalah penanganan kebakaran sudah terdapat APAR, fire smoke detector dan peringatan dilarang merokok. Sedangkan dalam penanganan kebanjiran posisi lemari lebih tinggi dari lantai dan sudah ada selokan untuk menampung air hujan. Menggunakan tinta yang seragam, jelas dan mudah dibaca. Kertas yang digunakan HVS A4 70 gram yang tidak mudah sobek. Map rekam medis terbuat dari bahan karton tebal dan sudah cukup kuat. Rak sudah roll o’pack yang terbuat dari besi sehingga tahan air, api dan panas, Menjaga kelembahan dan suhu secara berkala, dengan suhu berkisar antara 27oC dan kelembaban sebesar 56%. Untuk kerahasiaan rekam medis adalah terdapat peringatan di depan pintu masuk “Selain Petugas Rekam Medis Dilarang Masuk!”, Pintu ruangan rekam medis menggunakan finger print, hanya petugas rekam medis yang bisa membuka dan masuk kedalam ruangan. Seluruh petugas yang ada di rumah sakit disumpah untuk menjaga kerahasiaan informasi rekam medis baik itu informasi identitas pasien, diagnosis, riwayat penyakit, riwayat pemeriksaan maupun riwayat pengobatan.
The Most Effective Drugs in the Treatment of Myocarditis Disease
Authors: Nozimjon o’g’li Salomov Shoxabbos , Makhmudovich Aliev Husniddin
Published: April 2024

Myocarditis, characterized by inflammation of the heart muscle, presents a complex and challenging clinical scenario. This review explores the landscape of pharmacological interventions in the treatment of myocarditis, aiming to identify the most effective drugs in managing this inflammatory cardiac condition. A comprehensive analysis of current literature encompasses clinical trials, observational studies, and experimental models to evaluate the efficacy of various drug classes. From immunosuppressive agents to anti-inflammatory medications, the review delineates the mechanisms of action, safety profiles, and clinical outcomes associated with different drug interventions. The synthesis of evidence provides valuable insights into the pharmacotherapeutic strategies that demonstrate the highest efficacy in mitigating inflammation, preserving cardiac function, and improving patient outcomes in myocarditis
Changing Share Price After Announcement Of The Merger And Acquisitions By Acquiring Firms Is Significant Or Insignificant
Authors: Khan Arif Hasan , Belal Uddin
Published: April 2024

This Paper scrutinizes a model of merger and acquisition declaration of different companies in United Kingdom (Home Takeover) region and also other countries (Cross-Border Takeover) during the time period of 01 January 2019 to 30 June 2022 and finally displays the consequence of 50 Home takeover companies (UK companies acquired UK companies) and 50 cross- border companies (UK companies take over foreign companies) to recognize the post effect of merger andacquisition declaration on the stock prices of the target and acquired firms. Event Study Methodology has been used for this study, like, Average Abnormal Returns (AAR) and Cumulative Average Abnormal Returns (CAAR) are used to analyze the different event windows about the stock prices of the target and acquired firms. A paired sample investigation has also been directed by associating the Pre- and Post- announcement returns on stock prices for the event window of ± 5 days of the target and acquired firms. In the event windows, the stock price of the target firm's all is not positive CAAR but pointedly dissimilar from zero. In the home takeover figures, all the AAR and CAAR are not significant and some negative returns after the post-declaration prove about the primary investor's overreaction and efficient market hypothesis (EMH). There is no presence of positive implication in the cross-border pre-event return but only a positive implication returns in the home takeover pre-event return that is also significant at the 10% level.
ANÁLISE DO COMPORTAMENTO ASSIMÉTRICO DOS CUSTOS POR NATUREZA DOS GASTOS DE INDÚSTRIAS LISTADAS NAB3
Authors: Figueira Marquezan Luiz Henrique , Jung Carmen Luisa , Storgatto Taís dos Santos , Zonatto Vinícius Costa da Silva
Published: April 2024

O objetivo da pesquisa foi analisar o comportamento dos custos por natureza em relação às oscilações de volume de atividades em indústrias listadas na B3. Para isso, utilizou-se uma abordagem descritiva e quantitativa, com dados secundários das demonstrações contábeis de 2010 a 2018 das empresas da amostra. Os dados foram submetidos à análise de regressão de dados em painel. Os resultados encontrados apontam para assimetria no comportamento dos custos das indústrias analisadas, com maior ênfase para a redução do custo quando existe redução das vendas do que quando tem aumento. Para os gastos com pessoal, depreciação, produtos e insumos os achados apontam para assimetria. Os gastos de pessoal e depreciação revelam assimetria, oscilando apenas quando há redução das vendas, e sem relação estatisticamente significativa com aumentos nas vendas. Para produtos e insumos os resultados revelam que há assimetria no comportamento, sendo a maior ênfase para o aumento do custo quando há aumento das vendas. Tais resultados contribuem para professores, alunos e pesquisadores no processo de ensino e aprendizagem e na realização de novas pesquisas; para contadores e gestores contribui, pois os resultados buscam um melhor entendimento sobre o comportamento dos custos de suas empresas, possível pela análise por natureza do gasto.
ANÁLISE DO COMPORTAMENTO DOS CUSTOS NAS EMPRESAS DO SEGMENTO DE SERVIÇOS EDUCACIONAIS LISTADAS NA B3
Authors: Silva Cleiton Rodrigo Buarque , Silva Valdemir da , Santos Raidan Iago dos , Lima Elayne Victória Vieira Chagas de
Published: April 2024

O segmento educacional contribui para o desenvolvimento do Brasil por meio do avanço intelectual e cultural da sociedade. A partir dos anos 2000, com a criação do Fundo de Financiamento ao Estudante do Ensino Superior (FIES) e do Programa Universidade Para Todos (PROUNI), a educação superior privada expandiu consideravelmente. Diante disso, o mercado educacional brasileiro tornou-se altamente competitivo. Contudo, em 2015, o cenário mudou drasticamente em virtude da recessão econômica aliada à redução dos recursos do FIES. Assim, as organizações precisaram se adequar a um mercado incerto e em constante transformação por meio do gerenciamento e controle dos custos, buscando auxiliar a gestão no processo decisório. O objetivo desta pesquisa consiste em analisar o comportamento dos custos das empresas listadas na B3 durante o período de 2012 a 2019. A pesquisa classifica-se como descritiva, com abordagem quantitativa e análise documental, fazendo uso de demonstrações contábeis das empresas do segmento educacional listadas na B3, no período de 2012 a 2019. Os resultados demonstraram consecutivas variações positivas nas receitas, nos custos e nas despesas do segmento durante o período analisado, desacelerando a partir do período entre 2015 e 2016. A média do segmento evidenciou que, aproximadamente, 50% da Receita Líquida Vendida (RLV) é destinada a cobrir o Custo dos Produtos Vendidos (CPV). Na análise de correlação, observou-se uma correlação positiva e forte entre o CPV e a RLV (0,991).
MAPEAMENTO DE PROCESSOS PARA O GERENCIAMENTO DE CUSTOS: ESTUDO DE CASO EM UMA INDÚSTRIA DE LATICÍNIOS
Authors: Le Du Audrey , Nunes Rodolfo , Torquato Matheus
Published: April 2024

A apuração dos custos industriais, no caso a alocação dos custos indiretos, requer a escolha de critérios de rateio que podem trazer subjetividade aumentando o risco de arbitrariedade. O objetivo deste trabalho foi analisar a efetividade dos roteiros de processos como suporte para o custeio por meio de uma pesquisa ação. A empresa estudada é um laticínio com sede no Estado de São Paulo e instalações fabris no próprio estado e em outros. A pesquisa foi realizada na fábrica instalada no interior de São Paulo, que usa como critério de rateio as horas trabalhadas, calculadas a partir do mapeamento da produtividade de cada atividade fabril. Os achados evidenciaram a complexidade desse sistema de custeio atual, necessitando de capacitação para usuários e investimento para a base de dados. O uso do roteiro de processos apresenta falha no controle de alocação de mão de obra direta, distorcendo os custos, e não está alinhado ao ERP utilizado pela empresa em operações com tempo fixo. Os resultados também mostram oportunidades de melhoria no método de custeio, como a criação de centro de custos específicos para tornar a apuração de custos mais assertiva e otimizar as horas trabalhadas nas atividades de manufaturas com a utilização dos sistemas já implantados. A contribuição prática parte das decisões mais assertivas e eficientes das gestões em relação ao método de custeio utilizado nas companhias. E na questão teórica, as discussões sobre melhorias na gestão de custos e formas de mensuração são cruciais para a evolução do tema.
¿Qué es el overmanegement focalizado? Categoría propuesta: aportes a la disciplina
Authors: Podmoguilnye Marcelo
Published: April 2024

El overmanagement focalizado es una práctica de gestión provocativa pero a la vez positivista. Propone pensar las cosas de manera diferente a los demás y en un mayor grado de análisis de manera de intentar alcanzar la máxima optimización posible en el desarrollo de las variables diferenciales de un negocio. Es prestar atención extraordinaria a los detalles que rodean a los procesos organizacionales en todos los sentidos posibles. Es poner el énfasis con pensamiento estratégico y diferencial de lo que sería típico y razonable en las mejores prácticas corporativas.Es ser intencional donde nuestros competidores no lo son. Es gestionar en exceso las cosas que la mayoría de las empresas ignoran o no gestionan. Es ir más allá de los criterios de servicios tradicionales para encontrar propuestas nuevas e innovadoras de manera de mejorar las experiencias con nuestros actores.Es entender que el poder de un servicio u objetivo productivo radica en su capacidad para crear una conexión emocional en lugar de una conexión estrictamente racional, y que dicha experiencia emocional conlleve a la repetición de los negocios, y a la conformación de grupos de personas que se convierten en embajadores de nuestras marcas y objetivos productivos.Es centrarse en los pequeños detalles y en la sobregestión de los procesos o experiencias que marcan un diferencial para una organización.Es objetivo del presente trabajo definir el alcance de la técnica del overmanagement focalizado, entendiéndolo como un ámbito para la creación, gestación y gestión profunda de nuestras diferencialidades. Y finalmente evaluar su aplicabilidad y viabilidad en nuestras organizaciones y en los negocios del futuro.
PEMBINAAN TEORI TEKSDEALISME DAN PENELITIAN TERHADAP KARYA PUISI KONKRIT
Authors: SULIMAN MOHD SAIPUDDIN , MOHD NOR SHAHRUN NIZAL , AB JABAR NORDIANA , ZAKARIA NORAZIMAH , XUAN LIM YING , AFANDI AFIDATUL SYAZWANI
Published: April 2024

Makalah ini menekuni dimensi penciptaan teori teksdealisme menerusi aspek dasar pembangunan teori, rangka dasar teori serta pengakplikasian teori dalam karya sastera. Berikutnya, penelitian dibuat berdasarkan puisi konkrit Tri-V (verbal-vokal-visual) ciptaan Abdul Ghafar Ibrahim (AGI). Kajian ini mengaplikasi kaedah kualitatif berdasarkan teknik analisis kandungan (content analysis). Kaedah ini dipilih berikutan bersesuaian dengan teknik pengumpulan dan analisis data bersandarkan kepada teks yang dikaji. Dapatan kajian mendapati teori teksdelisme berfungsi dalam mengidentifikasi karya dan penyair yang unggul. Didapati prinsip teori ini paralel dengan horizon kepenyairan AGI yang cuba keluar daripada belenggu konvensional dan mencipta inovasi baharu bagi mewarnai jagat sastera tanah air. Diharapkan makalah ini dapat menjadi rujukan kepada pengkaji lain, pengkritik dan para pelajar aliran sastera yang ingin memanfaatkan teori teksdealisme dan pada masa yang sama mencipta pembaharuan dan inovasi dalam penciptaan puisi.

This paper explores the dimensions of textdealism theory creation through the basic aspects of theory development, a framework, and the application of theory in literary works. The research is based on Tri-V (verbal-vocal-visual) concrete poetry pioneered by Abdul Ghafar Ibrahim (AGI). This study applies qualitative method based on content analysis techniques. This approach was chosen due to its compatibility with the data collection and analysis techniques based on the text being studied. According to the findings, the textdealism theory is effective in identifying excellent poetry and poets. It was found out that this theoretical principle parallels with the horizon of AGI's poetry, which attempts to break out of the shackles of conventional and create new innovation to add much beauty to the literary world of the homeland. It is hoped that this paper can be a reference for other researchers, critics and literary studies majors who wish to utilize the theory along with renewal and innovation in the creation of poetry.