bluuebunny/crossref_metadata_2025 huggingface dataset:
HÀNH VI TÌNH DỤC KHÔNG AN TOÀN VÀ MỘT SỐ YẾU TỐ LIÊN QUAN CỦA NAM QUAN HỆ TÌNH DỤC ĐỒNG GIỚI TẠI THÀNH PHỐ CẦN THƠ NĂM 2021
Authors: Lý Anh Huy , Dương Minh Đức , Trần Ngọc Quế , Dáp Thanh Giang , Bùi Ngọc Phương Oanh , Phạm Lê Huyền Trang , Lê Minh Thái , Lưu Huỳnh Bảo Châu
Published: February 2023

Đặt vấn đề: Nhiễm HIV trong nhóm nam quan hệ tình dục đồng giới (MSM) hiện nay đang tăng rất nhanh do liên quan đến hành vi tình dục không an toàn. Mục tiêu nghiên cứu: Mô tả thực trạng hành vi tình dục không an toàn và một số yếu tố liên quan của MSM tại thành phố Cần Thơ năm 2021. Đối tượng và phương pháp nghiên cứu: Nghiên cứu cắt ngang sử dụng số liệu thứ cấp từ nghiên cứu điều tra giám sát trọng điểm HIV lồng ghép hành vi (HSS+) của MSM năm 2021, phân tích 300 MSM từ 16 tuổi trở lên. Kết quả: Tỷ lệ hành vi tình dục không an toàn của MSM là 68,7%. Một số yếu tố liên quan: nhóm tuổi <25 có tỷ lệ hành vi tình dục không an toàn cao gấp 2,3 lần nhóm tuổi ≥25 (KTC 95%:1,049-5,049); nhóm có quan hệ tình dục (QHTD) tập thể có tỷ lệ hành vi tình dục không an toàn cao gấp 7,2 lần so với nhóm còn lại (KTC 95%:1,023-56,840) và nhóm có sử dụng chất kích thích/chất gây nghiện có tỷ lệ hành vi tình dục không an toàn cao gấp gần 2,4 lần so với nhóm không sử dụng (KTC 95%:1,102-5,097). Kết luận: Tỷ lệ có hành vi tình dục không an toàn của MSM khá cao, địa phương cần tăng cường cung cấp kiến thức, dịch vụ dự phòng HIV/AIDS cho nhóm MSM nhằm góp phần giảm tỷ lệ nhiễm HIV.
IDENTITY POLITICS AND THREATS TO RELIGIOUS PLURALISM IN BUKITTINGGI
Authors: Endrizal Endrizal , Emzia Fajri
Published: February 2023

This study examined the issue of identity politics and the threat of pluralism in Bukittinggi, West Sumatra. The people of Bukittinggi, West Sumatra consisting of various ethnicities, tribes, races and cultures have been able to live with a spirit of pluralism and tolerance. Lately, the spirit of pluralism that has been run by the people of Bukittinggi, West Sumatra began to erode along with the strengthening of identity politics. The prominence of tribal, religious, racial and cultural identities becomes a serious problem in a plural society, because, the spirit of highlighting tribal, racial, cultural and religious identities excessively leads to claims of truth and the assumption that their tribes, races, religions and cultures are superior to cultures, races, tribes and religions outside their groups. In collecting data, this study uses qualitative methods. The research stages carried out are literature studies, observations, documentation, and interviews. The research will be guided by social theories such as identity politics and pluralism. The finding of this research is the strengthening of identity politics in Bukittinggi related to religious issues. Politically, religions outside of Islam are limited. This religious identity is further strengthened by the emergence of many religious groups in the midst of the people of Bukittinggi, West Sumatra. like Islamic organizations that massively bergeriliya in carrying out its mission to Islamize the entire community of west Sumatra. The movements carried out by islamic organizations seem to be strengthened by ethnicity (tribal), in the form of customs of the people of Bukittinggi, West Sumatra which is famous for its integration of customs and religions. Indirectly religion outside the religion of Islam its existence is limited in Bukittinggi, West Sumatra.
Dấu ấn sinh hoạt văn hoá trong truyện ngắn Đồng bằng Sông Cửu Long mười năm đầu thế kỷ XXI
Authors: Phạm Thị Lương
Published: February 2023

Truyện ngắn Đồng bằng sông Cửu Long mười năm đầu thế kỷ XXI đã để lại những dấu ấn văn hóa độc đáo mang đặc trưng của cư dân vùng sông nước. Văn học mỗi vùng miền cho thấy những dấu ấn văn hóa riêng biệt của vùng đất đó. Mọi bình diện văn hóa đều được khai thác để làm nổi bật đời sống vật chất, đời sống tinh thần của con người. Các nhà văn đã lồng ghép những khía cạnh văn hóa vào trong mọi mặt đời sống của nhân vật. Đời sống vật chất và đời sống tinh thần của con người nơi đây được khai thác ở chiều sâu góc nhìn văn hóa. Giá trị của những bình diện văn hóa tồn tại trong mọi mặt của đời sống. Tìm hiểu dấu ấn sinh hoạt văn hóa trong truyện ngắn Đồng bằng sông Cửu Long giai đoạn này, bài viết quy chiếu các khía cạnh từ góc nhìn địa văn hóa để làm nổi bật những dấu ấn sinh hoạt văn hóa tâm linh, văn hóa văn nghệ và văn hóa ẩm thực trong đời sống của cư dân đồng bằng.
RESEARCH ON VIETNAMESE MEDICINAL PLANTS WITH POTENTIAL IN THE TREATMENT OF COVID-19 DISEASE
Authors: Le Van Tuyen
Published: February 2023

Natural products have been considered the primary source of healthcare among the majority of the world’s population. In the therapeutic management of Covid-19, products of natural origin are a promising and potential medicinal source to treat this disease. Our research methodology is based on a review of recent articles reporting on the effect of medicinal plants on Covid-19. In this review, literature searches on medicinal plants which used to treat and prevent Covid-19 disease were conducted. From this research, several medicinal plants have received much research attention such as Astragalus mongholicus Bunge; Astragalus membranaceus (Fisch.) Bunge; Atractylodes lancea (Thunb.) DC.; Atractylodes chinensis (DC.) Koidz.; Atractylodes japonica Koidz.; and Atractylodes macrocephala Koidz.; Andrographis paniculata; Lonicera japonica; Scutellaria baicalensis Georgi. However, the definitive roles of these medicinal plants in cytokine storms and post-infection complications still need further investigation. And then, quality control and standardisation of medicinal plants-based products also need to be emphasized. Further investigations on differential effects as well as the quality and safety of herbal medicines should be required to ascertain their role in Covid-19 therapeutic management. Furthermore, herbal mixtures, medicinal plants, natural products, or their combination with possible anti-SARS-CoV-2 effects may hold promise and effectiveness in preventive and therapeutic support for Covid-19.
BỒI DƯỠNG PHONG CÁCH HỌC TẬP CỦA HỒ CHÍ MINH CHO SINH VIÊN HIỆN NAY
Authors: Trần Ngọc Ngân , Trần Ngọc Nhiều
Published: February 2023

Phong cách học tập của Chủ tịch Hồ Chí Minh là một phần quan trọng trong di sản vô giá mà Người đã để lại cho dân tộc. Với những nội dung sâu sắc, khoa học, đến nay phong cách học tập của Người vẫn còn nguyên giá trị. Hiện nay, sinh viên ở nước ta đã tích cực, chủ động học tập, tuy nhiên, cũng còn một bộ phận chưa xác định đúng đắn mục tiêu, thái độ và phương pháp học tập, nên gặp khó khăn trong quá trình phát triển, hoàn thiện nhân cách. Bài viết phân tích những đặc điểm cơ bản của phong cách học tập Hồ Chí Minh, trên cơ sở đó đề xuất các giải pháp để rèn luyện phong cách học tập Hồ Chí Minh cho sinh viên, đáp ứng mục tiêu, yêu cầu giáo dục - đào tạo trong thời kỳ đổi mới và hội nhập quốc tế.
THE IMPACT OF RECREATIONAL GAMES IN OUR SOCIETY
Authors: Mondal Manisha
Published: February 2023

Recreational Games are these activities where the primary purpose of the activity in participation, with related goals of improved physical fitness, for and social involvement often prominent. It is less stressful, both physically nd mentally on the participants. These are lower expectations regarding both performance and commitment to the sports in the recreational games in one of the most important area and it also create positive inter-relationship to every person. Recreational games are often done for enjoyment, amusement or pleasure and are considered to be ‘fun’. In our busy schedule, recreational games gives us oxygen and in this way our new generation can explore many things for the development of society.
Research on Data Processing Security System Based on Bio commercial technology and Artificial Intelligence
Authors: Tang Li  , Zhao Zhiyu  , Li Biaoqi  , Xu Min
Published: February 2023

Data security has become an increasingly important concern for organizations and individuals in the digital age. To address this issue, there has been growing interest in using bio-commercial technology and artificial intelligence (AI) to develop innovative security solutions. This paper presents a research study on the development of a data processing secure new entrants in the market for medical devices in Germany can use the use of biometric data, such as fingerprints, iris scans, and voice recognition, in combination with AI algorithms to enhance the security of data processing. The paper provides an overview of the technical framework and architecture of the proposed system, and evaluates its effectiveness in comparison to traditional security measures. The study uses a combination of quantitative and qualitative research methods, including surveys, interviews, and simulations, to collect and analyze data on the performance, accuracy, and usability of the proposed system. The results suggest that the data processing security system based on bio-commercial technology and AI is highly effective in preventing unauthorized access and enhancing data protection. The system provides a high level of accuracy, speed, and user-friendliness, making it a viable alternative to traditional security measures. The paper concludes with a discussion of the implications of the study for the field of data security and future research directions.
Multi-Source Data Interpretation For Field Scale Precision Management In Healthcare Industry
Authors: Zhiying Huang  , Shaoxiong Hu  , Yanqing Liang
Published: February 2023

Precision management is a critical component of healthcare, where access to accurate and timely data is essential for effective decision-making. In the healthcare industry, precision management involves the use of multiple data sources to understand patient needs and improve health outcomes. Multi-source data interpretation, specifically at the field scale, is becoming increasingly popular as a means to obtain a comprehensive view of patient care. Field scale precision management in healthcare involves the integration of data from various sources, including electronic health records, patient-generated data, and social determinants of health. Through the use of advanced analytics and machine learning algorithms, this data can be processed and interpreted to identify patterns, trends, and insights that can help healthcare providers make more informed decisions. The application of multi-source data interpretation in healthcare is particularly important because it allows for a more holistic view of patient health, taking into account factors beyond traditional medical metrics. For example, social determinants of health, such as access to healthy food and safe housing, can have a significant impact on patient health outcomes, and these factors can be identified through the analysis of non-medical data sources. Overall, the use of multi-source data interpretation for field scale precision management in healthcare has the potential to significantly improve patient outcomes by providing healthcare providers with a more complete understanding of patient needs and circumstances. With advances in technology and analytics, healthcare providers can better harness the power of data to optimize patient care and improve health outcomes at scale.
Path Analysis of University Education Management based on Biotechnology
Authors: Ying Peng
Published: February 2023

University education management is a complex process that involves multiple factors and variables. Biotechnology is an emerging field that is transforming various aspects of higher education, including curriculum design, research, and innovation. This abstract explores the use of path analysis in university education management based on biotechnology. The study highlights the potential of path analysis in identifying the causal relationships between various factors in university education management. The study reviews the various variables that could influence university education management in the context of biotechnology, such as curriculum design, faculty development, student outcomes, and institutional innovation. The study examines the benefits of path analysis for university education management based on biotechnology, such as the ability to identify key variables and prioritize resources, improve decision-making, and enhance the overall quality of education. The study also discusses the challenges of implementing path analysis in university education management, such as data availability, data quality, and statistical analysis. The study concludes that path analysis is a valuable tool for university education management based on biotechnology, enabling the identification of causal relationships and the development of evidence-based strategies for improving education quality and outcomes. The integration of biotechnology in university education management can enhance the quality of education, improve research and innovation, and contribute to the growth of the biotechnology industry.
The potential for artificial intelligence in healthcare
Authors: Zuocheng Wen  , Hua Huang
Published: February 2023

Artificial intelligence (AI) is emerging as a promising technology for transforming the healthcare industry. The potential of AI lies in its ability to analyze vast amounts of data and identify patterns that can lead to better diagnosis, treatment, and patient outcomes. This abstract explores the potential for artificial intelligence in healthcare. The study highlights the various applications of AI in healthcare, such as medical imaging analysis, drug discovery, and personalized medicine. The study reviews the benefits of AI in healthcare, such as increased efficiency, accuracy, and cost savings. The study also examines the challenges of implementing AI in healthcare, such as data security and privacy concerns and regulatory barriers. The study concludes that artificial intelligence has the potential to revolutionize the healthcare industry, enabling more accurate diagnoses, personalized treatments, and improved patient outcomes. As the technology continues to advance, the healthcare industry will need to address the challenges of implementing AI while maintaining patient privacy and regulatory compliance. Despite these challenges, the benefits of AI in healthcare are clear, and the technology is poised to transform the industry in the coming years.
Interactive development of cross-border e-commerce and new Internet economy in digital health sector
Authors: Changsong Song
Published: February 2023

Cross-border e-commerce and the new Internet economy are rapidly evolving sectors in the digital health industry. The development of interactive platforms is enabling businesses to create innovative solutions that improve access to healthcare products and services, especially in regions with limited resources. The integration of data analytics, artificial intelligence, and other emerging technologies in the digital health sector is transforming the way healthcare services are delivered. This abstract explores the interactive development of cross-border e-commerce and the new Internet economy in the digital health sector, highlighting the opportunities and challenges faced by businesses. The study reviews the potential of e-commerce platforms to expand the reach of healthcare products and services across borders, the impact of government regulations, and the role of emerging technologies in enhancing healthcare accessibility and affordability. The study concludes that interactive platforms, such as e-commerce, play a vital role in the development of the digital health sector, providing opportunities for businesses to innovate and create solutions that address the needs of patients and healthcare providers in diverse geographical locations.
Identifying the drawbacks of joint patents: An evaluation of IPR sharing in R&D alliances in Biotechnology Firms in Singapore
Authors: Dr. Muhammad Haseeb  , Dr. Nira Hariyatie Hartani
Published: February 2023

R&D alliances in the biotechnology industry have always been common in order to fulfill the demands and needs of the involved parties to carry out their innovation processes. The increasing trend of R&D alliances in the biotechnology industry in Singapore has also promoted IPR sharing in R&D alliances. This mechanism has promoted the concept of joint patents in this regard. Thus, the present study focused on the drawbacks of joint patents in R&D alliances in biotech firms in Singapore. For this purpose, semi-structured interviews were conducted with five employers from different biotech firms in Singapore. The collected data was then analyzed using NVivo software, and project map and tree maps were formulated for each research objective. The results obtained from this study showed that R&D alliances are effective in improving the financial and innovation performance of biotechnology firms. It has also been observed that IPR sharing in these alliances is effective in promoting technology and knowledge transfer. However, various drawbacks of joint patents were also observed, including financial issues, technology-related issues, and legal issues.
La realidad virtual y su efecto en la habilidad espacial: un caso de estudio enfocado en la enseñanza de la geometría descriptiva
Authors: Yarin Yasser , Gamarra Chinchay Hugo Eliseo
Published: February 2023

This study describes a case study on the use of virtual reality in the teaching of descriptive geometry for engineering students. The objective was to develop a learning experience with virtual reality that improves spatial ability, a non-immersive 3D environment was used with the purpose of facilitating the two-dimensional representation in the intersection of solids. This quasi-experimental work used a first group defined as an experimental group that participated in a workshop on the intersection of polyhedrons and the intersection of surfaces of revolution using virtual reality as a means to interact with the intercepted solids, while a second group, the control group developed the same issues with two-dimensional images of intercepted solids. The evaluation instrument measured the dimensions of mental rotation and mental folding, this was applied to both groups at the beginning and at the end of the workshop, managing to measure their spatial ability for the rigid and non-rigid transformation of objects. Statistical analysis allowed identifying a significant difference between the experimental and control groups, concluding that the developed workshop had a positive effect on the spatial ability of the groups of students participating in the study.

Este estudio describe un caso de estudio sobre el uso de la realidad virtual en la enseñanza de la geometría descriptiva para estudiantes de ingeniería. El objetivo fue desarrollar una experiencia de aprendizaje con la realidad virtual que mejore la habilidad espacial, se utilizó un entorno no inmersivo 3D con el propósito de facilitar la representación bidimensional en la intersección de sólidos. Este trabajo cuasiexperimental utilizo un primer grupo definido como grupo experimental que participo en un taller sobre la intersección de poliedros y la intersección de superficies de revolución utilizando la realidad virtual como medio para interactuar con los sólidos interceptados, mientras que un segundo grupo, el grupo control desarrollo los mismos temas con imágenes bidimensionales de los sólidos interceptados. El instrumento de evaluación midió las dimensiones de rotación mental y plegado mental, este fue aplicado a ambos grupos al inicio y al término del taller, logrando medir su habilidad espacial para la transformación rígida y no rígida de objetos. El análisis estadístico permitió identificar una diferencia significativa entre le grupo experimental y control, concluyendo que el taller desarrollado tuvo un efecto positivo en la habilidad espacial de los grupos de estudiantes que participan en el estudio.
Revisión sistemática de los entornos digitales inmersivos tridimensionales en la enseñanza de la programación
Authors: López Solórzano Juan Gabriel , Ángel Rueda Christian Jonathan
Published: February 2023

Currently, three-dimensional immersive digital environments (TIDE) have been applied to the educational field, being Augmented Reality, Virtual Reality and Virtual Worlds the most representative technologies. Currently in the literature there are systematic reviews that address each technology separately, making evident the need for a study covering all technologies and more specifically applied to the teaching and learning of computer programming. In the present study, 64 research studies related to the teaching of computer programming at different educational levels were analyzed. Among the main results, 57 studies developed their own tool or application, which shows the little or no practical usefulness of the developments since they are only used for experiments. In addition, most of the works present the benefits of their tools and only 12 studies mention a problem when using the TIDE in the teaching of programming. Finally, the use of TIDE is highlighted mainly for teaching the topic of control structures in programming. This topic is essential since it allows students to modify the execution flow of program instructions.

En la actualidad los entornos digitales inmersivos tridimensionales (EDIT) se han aplicado al ámbito educativo, siendo la Realidad Aumentada, Realidad Virtual y los Mundos Virtuales las tecnologías más representativas. Actualmente en la literatura existen revisiones sistemáticas que abordan cada tecnología por separado, haciendo evidente la necesidad de un estudio que abarque todas las tecnologías y más puntualmente que se aplique a la enseñanza aprendizaje de la programación de computadoras. En el presente estudio se analizaron 64 investigaciones que están relacionadas a la enseñanza de algún tema sobre la programación de computadoras en diversos niveles educativos. Entre los principales resultados se destaca que 57 estudios desarrollaron su propia herramienta o aplicación, lo cual pone de manifiesto la poca o nula utilidad práctica de los desarrollos puesto que solamente se utilizan para sus experimentos. Además, la mayoría de los trabajos presentan las bondades de sus herramientas y solamente 12 estudios mencionan algún problema al utilizar los EDIT en la enseñanza de la programación. Finalmente, se destaca el uso de los EDIT principalmente para la enseñanza del tema de estructuras de control en programación. Este tema es primordial ya que permite a los estudiantes modificar el flujo de ejecución de las instrucciones de un programa.
The current state of graphical abstracts and how to create good graphical abstracts
Authors: Lee Jieun , Yoo Jeong-Ju
Published: February 2023

Graphical abstracts (GAs), also known as visual abstracts, are powerful tools for communicating complex information and ideas clearly and concisely. These visual representations aim to capture the essential findings and central message of a research study, allowing the audience to understand and remember its content quickly. This review article describes the current state of GAs, including their benefits, limitations, and future directions in the development of GAs. It also presents methods and tips for producing a GA. In Korea, more than 10 medical journals have introduced GAs from 2021 to 2022. The number of citations was higher in articles with GAs than in those without GAs in the top 10 gastroenterology journals. There are five types of GAs: conceptual diagrams, flowcharts, infographics, iconographic abstracts, and photograph-like illustrations. A limitation of the GA system is the absence of a universal standard for GAs. The key steps for creating a GA are as follows: (1) start by identifying the main message; (2) choose an appropriate visual style; (3) draw an easy-to-understand graphic; (4) use colors and other design elements; and (5) request feedback. Available tools that are useful for creating GAs include Microsoft PowerPoint, Mind the Graph, Biorender, and Canva. Another effective method is collaborating with experts. Artificial intelligence will soon be able to produce GAs more efficiently from raw data or manuscripts, which will help researchers draw GAs more easily. GAs have become a crucial art for researchers to master, and their use is expected to expand in the future.
Impact and perceived value of the revolutionary advent of artificial intelligence in research and publishing among researchers: a survey-based descriptive study
Authors: Thomas Riya , Bhosale Uttkarsha , Shukla Kriti , Kapadia Anupama
Published: February 2023

Purpose: This study was conducted to understand the perceptions and awareness of artificial intelligence (AI) in the academic publishing landscape.Methods: We conducted a global survey entitled “Role and impact of AI on the future of academic publishing” to understand the impact of the AI wave in the scholarly publishing domain. This English-language survey was open to all researchers, authors, editors, publishers, and other stakeholders in the scholarly community. Conducted between August and October 2021, the survey received responses from around 212 universities across 54 countries.Results: Out of 365 respondents, about 93% belonged to the age groups of 18–34 and 35–54 years. While 50% of the respondents selected plagiarism detection as the most widely known AI-based application, image recognition (42%), data analytics (40%), and language enhancement (39%) were some other known applications of AI. The respondents also expressed the opinion that the academic publishing landscape will significantly benefit from AI. However, the major challenges restraining the large-scale adoption of AI, as expressed by 93% of the respondents, were limited knowledge and expertise, as well as difficulties in integrating AI-based solutions into existing IT infrastructure.Conclusion: The survey responses reflected the necessity of AI in research and publishing. This study suggests possible ways to support a smooth transition. This can be best achieved by educating and creating awareness to ease possible fears and hesitation, and to actualize the promising benefits of AI.
Current status and demand for educational activities on publication ethics by academic organizations in Korea: a descriptive study
Authors: Hur Yera , Yun Cheol-Heui
Published: February 2023

Purpose: This study aimed to examine the following overarching issues: the current status of research and publication ethics training conducted in Korean academic organizations and what needs to be done to reinforce research and publication ethics training.Methods: A survey with 12 items was examined in a pilot survey, followed by a main survey that was distributed to 2,487 academic organizations. A second survey, which contained six additional questions, was dispatched to the same subjects. The results of each survey were analyzed by descriptive statistical analysis, content analysis, and comparative analysis.Results: More than half of the academic organizations provided research and publication ethics training programs, with humanities and social sciences organizations giving more training than the others (χ2=11.190, df=2, P=0.004). The results showed that research and publication ethics training was held mostly once and less than an hour per year, mainly in a lecture format. No significant difference was found in the training content among academic fields. The academic organizations preferred case-based discussion training methods and wanted expert instructors who could give tailored training with examples.Conclusion: A systematic training program that can develop ethics instructors tailored to specific academic fields and financial support from academic organizations can help scholarly editors resolve the apparent gap between the real and the ideal in ethics training, and ultimately to achieve the competency needed to train their own experts.
Monitoring the Improvement of the Urban Environment through Exceptional Communication with the Population (Based on the Materials of the Kirov Region)
Authors: Starikova Mariya Mikhailovna
Published: February 2023

For the improvement of cities, the project «Formation of a comfortable urban environment» has been implemented in Russia for several years. In many regions, a number of their own landscaping projects are being carried out. The analysis of feedback from the population can be used as a tool for monitoring and measuring the effectiveness of urban improvement programs. The purpose of the work is to evaluate the results of the implementation of improvement programs in Kirov, the regional center of the Kirov region, taking into account the opinions of the population as the main recipient of these programs. The object of the study is the current state of improvement of the city of Kirov. The subject of the study is the analysis of landscaping in a number of areas (road transport, house and communal infrastructure, accessibility and quality of work of socio-cultural facilities) through feedback from the population. The study was carried out by analyzing official statistics data, a formalized survey of the population and interviews with experts. Two clusters of citizens were identified according to the level of satisfaction with the current state of the city's improvement, a large proportion is a cluster with a low level of satisfaction. However, 60% of residents believe that the quality of the urban environment has been gradually changing for the better over the past few years. The majority of respondents have minimal experience of involvement in the co-development of the urban environment, usually expressed in voting for objects for priority improvement. The study made it possible to identify and concretize the problems of the urban environment: disproportions in the improvement of central and suburban neighborhoods, catching up with the nature of infrastructure development during housing construction, insufficient road capacity, insufficient landscaping of park areas and public recreation areas. A scheme for solving the identified problems of landscaping is proposed, combining two directions: urban planning and communication and managerial.
Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes
Authors: Raz Amelie A , Vida Gabriela S , Stern Sarah R , Mahadevaraju Sharvani , Fingerhut Jaclyn M , Viveiros Jennifer M , Pal Soumitra , Grey Jasmine R , Grace Mara R , Berry Cameron W , Li Hongjie , Janssens Jasper , Saelens Wouter , Shao Zhantao , Hu Chun , Yamashita Yukiko M , Przytycka Teresa , Oliver Brian , Brill Julie A , Krause Henry , Matunis Erika L , White-Cooper Helen , DiNardo Stephen , Fuller Margaret T
Published: February 2023

Proper differentiation of sperm from germline stem cells, essential for production of the next generation, requires dramatic changes in gene expression that drive remodeling of almost all cellular components, from chromatin to organelles to cell shape itself. Here, we provide a single nucleus and single cell RNA-seq resource covering all of spermatogenesis in Drosophila starting from in-depth analysis of adult testis single nucleus RNA-seq (snRNA-seq) data from the Fly Cell Atlas (FCA) study. With over 44,000 nuclei and 6000 cells analyzed, the data provide identification of rare cell types, mapping of intermediate steps in differentiation, and the potential to identify new factors impacting fertility or controlling differentiation of germline and supporting somatic cells. We justify assignment of key germline and somatic cell types using combinations of known markers, in situ hybridization, and analysis of extant protein traps. Comparison of single cell and single nucleus datasets proved particularly revealing of dynamic developmental transitions in germline differentiation. To complement the web-based portals for data analysis hosted by the FCA, we provide datasets compatible with commonly used software such as Seurat and Monocle. The foundation provided here will enable communities studying spermatogenesis to interrogate the datasets to identify candidate genes to test for function in vivo.
Comportamento e consumo sustentável em viagens de turismo por natureza
Authors: Da Silva Armistrong Martins , Da Silva Áurio Lúcio Leocádio , Braga Núbia Costa de Almeida , Guimarães Daniel Barboza
Published: February 2023

Recentemente, as discussões envolvendo a temática da sustentabilidade em todo o mundo, passaram a focar os padrões de consumo da sociedade como um dos principais causadores dos problemas socioambientais, inclusive nas atividades de turismo. Nesse contexto, o objetivo do estudo é investigar se as variáveis perspectiva de tempo, capital cultural e orientação para o consumo sustentável, influenciam no comportamento sustentável em viagens de turismo por natureza. A pesquisa é quantitativa e descritiva, visando analisar as relações entre as variáveis que compõe os construtos teóricos do consumo sustentável. Foi realizada uma pesquisa survey com 313 turistas, a partir da qual foram aplicadas análises multivariadas de dados. Os resultados mostram que os três construtos analisados (consumo sustentável, perspectiva de tempo e capital cultural) apresentam influências positivas no comportamento sustentável do turista. Os resultados podem contribuir para o processo de tomada de decisão gerencial nos setores públicos e privados, ajudando a estabelecer um planejamento e estratégias de marketing para o desenvolvimento dos destinos turísticos, assim como, orientar o comportamento sustentável do consumidor. O estudo aprofunda os conhecimentos sobre à teoria do comportamento sustentável e colabora para o entendimento das mudanças de hábitos e práticas de consumo sustentáveis em viagem de turismo por natureza.
Criptoactivos: desafíos contables desde las orientaciones del CINIIF en un contexto actual
Authors: Candido Joelma Cordeiro
Published: February 2023

El objetivo de este trabajo consistió en presentar recomendaciones para la registración contable de los criptoactivos, considerando las orientaciones del Consejo de Interpretación de las Normas de Información Financiera (en adelante, CINIIF), en vista que hasta la fecha el organismo emisor no ha incluido en su agenda el estudio de emisión de una norma específica para guiar la registración de estas actividades. Para alcanzar el objetivo propuesto se realizó un análisis de las Normas Internacionales de Contabilidad emitidas hasta la fecha y de los pronunciamientos y normativas internas que emite algunos Estados, contrastando con el parecer de la doctrina. Se concluye que la naturaleza de  los CA es  adaptable a varios tipos de transacciones que van más allá de Intangibles mantenido para la venta y  materias primas cotizadas,  porque en el campo práctico existe un número creciente de entidades que poseen CA como un mecanismo de inversión y medios de pago,  para estos casos los estándares propuestos no pueden aplicarse, entonces es necesario una revisión  conceptual de las normas existentes o la emisión de una nueva guía para orientar el tratamiento contable de los CA.
Association of Junk Food Consumption, Daily Screen Time and Daily Physical Activity with Overweight and Obesity among School Children Aged 8-10 Years- A Cross-sectional Case-control Study
Authors: John Roshan Joseph , Kailas Lalitha , Pillai Swapna K
Published: February 2023

Introduction: The prevalence of obesity among school children in Kerala is on a steady rise. Consumption of food with high glycaemic index, change in sleep patterns, reduced physical activity and the use of screen has been linked to obesity in children. Published literature on this association is scarce from urban Thiruvananthapuram, hence, the present study. Aim: To identify the association of various risk factors such as frequency of junk food consumption, dietary preferences, physical activity and daily screen time and weight related disorders among school going children (8-10 years) in Thiruvananthapuram. Materials and Methods: The present cross-sectional casecontrol study was conducted in one Rural Government School (Venjaramoodu Government Upper Primary School) and one Urban Private School (S.N. Public School, Chenkottukonam) of Thiruvananthapuram, Kerala, India, and enrolled school going children aged 8-10 years with higher than recommended Body Mass Index (BMI) for age as cases, age and gendermatched children with normal BMI as controls. Participants with BMI above 23rd and below 27th adult equivalent for age and gender were considered overweight and those above 27th adult equivalent for age and gender were considered as obese. A structured questionnaire was sent home with the children, and the parents were requested to answer the questions along with written informed consent. Socio-demographic parameters, anthropometric measurements were obtained by trained staff, dietary habits, and details regarding physical activity and screen usage were collected. Variables were categorised according to the standard recommendations by World Health Organisation (WHO) and Indian Association of Paediatrics (IAP). Variables were expressed as frequencies and the tests of significance used were Chi-square test and Odds ratio, to express the strength of association between parameters. A p-value <0.05 was considered statistically significant. Results: The mean age of cases and controls was nine years. A total of 708 school children were screened and 352 participants (175 cases and 177 controls) were enrolled in the present study. The BMI of cases was 29.3 kg/m2 and of controls was 20.2 kg/ m2 . Higher than recommended screen time (p<0.001), more frequent junk food consumption (p<0.001) and lack of physical activity (p<0.001) were found to be significantly associated with obesity and overweight. Dietary preference was not associated with obesity or overweight and obesity and overweight was more common in children studying in private schools (p<0.001). Conclusion: Reducing screen time, reducing junk food consumption and increasing physical activity will help in reducing the prevalence of life style diseases among school children. Further evaluation is necessary to determine the factors contributing to the increased prevalence of these disorders in private schools.
Association of C677T Polymorphism of Methylenetetrahydrofolate Reductase with Metabolic Syndrome among Eastern Indian Women: A Case-control Study
Authors: Firdoush Kaziashique , Maji Rituparna , Banerjee Ritam , Dasgupta Anindya
Published: February 2023

Introduction: Polymorphisms of Methylene Tetrahydrofolate Reductase (MTHFR) gene have been associated with hyperhomocysteinaemia, which in turn may lead to hypertension, insulin resistance and abnormality of lipid metabolism. All these abnormalities are also components of Metabolic Syndrome (MetS). Thus, there is possibility of an association between MetS and MTHFR polymorphism. Literature search revealed paucity of data on this association, particularly from India. Aim: To evaluate the association of C677T polymorphism of MTHFR gene with MetS, among women of eastern Indian population. Materials and Methods: A hospital-based case-control study was conducted in the Department of Biochemistry, Calcutta National Medical College, Kolkata, West Bengal, India, between December 2016 to June 2018. Anthropometric and biochemical profiling of all 417 study subjects were done. Genetic workup was done by Polymerase Chain Reaction (PCR), using suitable primer, followed by restriction fragment length polymorphism analysis using Hinf 1 enzyme to identify MTHFR C677T polymorphism. Subjects were divided into two groups according to presence or absence of MetS as per International Diabetic Federation worldwide definition and compared with Mann-Whitney U Test. Logistic regression analysis was also performed. Results: Out of enrolled 417 female subjects, 243 were categorised as MetS group. Mean age (in years), of MetS group (48.70±9.03) was found to be significantly higher (p<0.001) than that of control group (42.83±10.90). A total of 45 (25%) females with MetS exhibited the presence of heterozygous CT genotype; that was significantly higher (p=0.026) than the non MetS group 21 (14.9%). The mutant T allele frequency was also significantly higher among the subjects suffering from MetS; 45 (12.5%)compared to 21 (7.4%) in the control group (p=0.036). Multiple logistic regression analysis revealed the odds of developing MetS among subjects with heterozygous CT genotype was 7.721 times (CI: 2.38-25.05) compared to those with wild genotype. Conclusion: C677T polymorphism of MTHFR gene was associated with the occurrence of MetS among woman.
Spectrum of Renal Involvement in Cancer Patients: A Cross-sectional Descriptive Study
Authors: Ngullie Pideno , Nath Smita , Raizada Alpana , Agarwal Sunil
Published: February 2023

Introduction: Cancer is associated with multiple renal manifestations like Acute Kidney Injury (AKI), Chronic Kidney Disease (CKD), proteinuria, and electrolyte imbalance. The reason behind renal dysfunction in cancer patients is multifactorial and can be attributed to underlying cancer and treatment modalities, in addition to co-morbidities surgical procedures and infections. Aim: To assess the spectrum of renal involvement in cancer patients presenting at a tertiary care hospital. Materials and Methods: The cross-sectional descriptive study, was conducted in the Department of Medicine of University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. One hundred consecutive patients referred for nephrology consultation with diagnosed cancer, irrespective of cancer aetiology between the age group of 15-70 years with deranged kidney function test were recruited. Detailed medical and treatment history, including the type of cancer-solid or haematological, cancer status-cured or continuing, treatment given-chemotherapy, radiotherapy or surgery or a combination and associated co-morbidities like diabetes mellitus and hypertension were recorded. Routine investigations and special investigations, including assessment of estimated Glomerular Filtration Rate (eGFR) and estimation of Albumin-Creatinine Ration (ACR) was done. Patients were then segregated, based on their kidney function test into groups with AKI or CKD and underlying cause was valuated. Summary statistics was presented as mean, median or frequency and data analysed using Statistical Package of Social Sciences (SPSS) version 24.0. Results: The mean age of the study population was 53.73±12.20 years with 63% male and 37% female participants; 87% patients had solid cancers, while 13% had haematological cancers. The median duration, since the diagnosis was seven months and the patients were undergoing chemotherapy, radiotherapy or a combination of both; seven patients had surgery for underlying malignancy and an additional six had received chemotherapy or radiation therapy along with surgery. At the time of recruitment, 78% patients had AKI and 22% patients were diagnosed with CKD. Chemotherapy-induced nephropathy was the most common cause of AKI (n=46). In the CKD group diabetes (n=7) was the most common aetiology. Conclusion: The kidneys in cancer patients can be involved in a number of ways, as a consequence of the cancer itself, its treatment, superimposed infections or associated comorbidities. Chemotherapy-induced nephropathy is the most common cause of AKI, whereas, diabetes is the most common cause of CKD in cancer patients.
Health-Related Quality of Life in Children With Cochlear Implants From Parents’ Perspective
Authors: Rochd Sara , Benhoummad Othmane , Lakhdar Youssef , Salhi Salma , Lhadj Mohamed Amine Ait , Rochdi Youssef , Raji Abdelaziz
Published: February 2023

Background and Objectives: To evaluate the health-related quality of life (HRQoL) in parents of children with cochlear implants and assess influencing factors. These data can enable practitioners to support patients and their families in utilizing the cochlear implant and its benefits to the fullest extent.Subjects and Methods: A retrospective descriptive and analytic study was conducted at the Implantation center Mohammed VI. Parents of cochlear implant patients were asked to fill out forms and answer a questionnaire. Participants included parents of children <15 years old who underwent unilateral cochlear implantation between January 2009 and December 2019, presenting with bilateral severe to profound neurosensory deafness. Participants completed the children with cochlear implantation: parent’s perspective (CCIPP) HRQoL questionnaire.Results: The mean age of the children was 6.49±2.55 years. The mean time between implantation for each patient and this study was calculated as 4.33±2.05 years. There was a positive correlation between this variable and the following subscales: communication, well-being and happiness, and the process of implantation. For these subscales, the score was higher as the delay was greater. Parents of children who received speech therapy before implantation were more satisfied on the following subscales: communication, general functioning, well-being and happiness, implantation process, implantation effectiveness, and support for the child.Conclusions: The HRQoL is better in families of children who received their implant at an early age. This finding raises awareness of the importance of systemic screening in newborns.
Technical Supplement for Network Control
Authors: Layefa Omamoke , Bunakiye Richard Japheth , John Yinembele Egbure, , Mamuyovwi Helen Ofualagba
Published: February 2023

Networking in computer science is the connection of two or more computers electronically with the sole aim of data or peripheral sharing. As the computers and peripherals connected to a network increases, using routers and switches alone is no longer reliable to contain broadcast traffic. Therefore this research employed VLAN technology to improve the performance of an extended star network topology by dividing a single switching network into a number of overlaying virtual networks called VLANs that can accommodate various functionalities, security needs and easy administration. For Inter-VLAN routing, a layer 3 switch that support 802.1Q trunking on a fast Ethernet or GigabitEthernet interface was used. This study is conducted using a white-box approach and the waterfall methodology to design, simulate and compare. After configuration, it was seen that the presence of failure in the main network is abstracted from the network users as the VLANS is configured logically to access and share resource with systems on all blocks. Subsequently, A ring topology can be introduced to the system were each block will have a backup switch and can serve as a backup for the block nearest to it. Also a Dual ISP can be introduced to provide steady internet access.