bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengenalan Eco-Enzyme Di Lingkungan Sdn 03 Sumberporong Lawang Kabupaten Malang
Authors: Fathi Pusposari Luthfiya , Azis Abdul , Wizarotun Nisa Amalia , Kwantari Enggar , Dwi Anggraini Mentari Cahya , Shoumiyah Rohmatus
Published: February 2023

Sampah merupakan salah satu permasalahan yang penting di seluruh dunia, utamanyaIndonesia. Pada tahun 2021, berdasarkan data The Economics Intelligence Unit, Indonesia tercatatsebagai negara penghasil sampah terbesar kedua di dunia setelah China. Seorang pendiri AsosiasiPertanian Organik Thailand, Dr. Rosukon Poompanvong, yang telah melakukan penelitan sejak1980-an berhasil mengembangkan eco-enzyme. Program ini bertujuan untuk pengenalan ecoenzymepada para siswa di SDN 03 Sumberporong agar dapat memanfaatkan limbah dapur organikyang ada di rumah maupun di sekolah menjadi cairan multifungsi yang kaya manfaat. Kegiatan inidilaksanakan dengan penyampaian materi sebagai pengenalan, diskusi, dan praktik.
CHARACTERIZATION OF RHIZOBIA FROM DIFFERENT LEGUMINOUS PLANT RHIZOSPHERE
Authors: Gondaliya Nidhi , Khushbu Trambadiya , Patel Ankita , Shah Hiral
Published: February 2023

Agriculture need novel technology as well as sustainability for high crop yield with good nutritional values. Microbes play an essential role in maintaining soil fertility. Specially Rhizobia contribute in supplying nitrogen source in soil as well as to plant roots. Rhizospheric microbes have major role in balancing nutrients. Present study represents primary understanding of different rhizobia species from different leguminous plant
THE CONSTRUCTIVE WORKS OF SARDAR VALLABHBHAI PATEL, THE CREATOR OF UNBROKEN INDIA.
(IN CONTEXT WITH AHMEDABAD MUNICIPALITY)
Authors: Patel Vipulkumar Dahyabhai
Published: February 2023

Sardar Patel is one of the most foremost figures in the annals of the Indian national movement. Due to his versatile personality he made many fold contribution to the national causes during the struggle for freedom. The great achievement of Vallabhbhai Patel is his successful completion of various satyagraha movements, particularly the Satyagraha at Kheda which made him a popular leader among the people and at Bardoli which earned him the coveted title of “Sardar” and him an idol for subsequent movements and developments in the Indian National struggle. The role of Sardar Patel in constructive activities are admirable. The present study focuses on the great achievement of Sardar Patel in the fields of social, educational and women empowerment. I used analytical, descriptive and historical method to complete my work.
NATURAL GUJARATI LANGUAGE INTERFACE TO DIRECT RETRIEVAL FROM DIVERSE INDIAN AGRICULTURE SOURCES
Authors: Shah Axita , Pareek Jyoti
Published: February 2023

A major part of India's economy is based on agriculture. Indian Government and private organizations offer a lot of different forms of information and knowledge to be beneficial to the agriculture community. It is essential that this information reaches to the needy in his own language with very little effort. At that time, when other helping hand is not accessible to answer them, Automated Digital solution is blessing to acquire solution of the agriculture stake holder’s questions related to agriculture facts, features and functionalities. And that to be provided as speedy direct retrieval, not the transformed or linked solution. In Agriculture AI is applied at different phases of the crop cultivation system, but as per the study and review, we do not have direct solution in mind. After the innovation, we have found and patented the solution in India (Shah and Pareek, A Mechanized Intellect Orchestration, Filed as Patent). Here, in this paper we have described the detail framework in Indian agriculture context. We have found the result of the retrieval through the proposed process and that’s significant to work towards this novice solution.
भारतीय सन्दर्भ में सामाजिक भूमिका संवर्द्धन एवं समावेशी शिक्षा: एक अध्ययन
Authors: कुमार अखिलेश , तिवारी प्रवीण कुमार
Published: February 2023

निःशक्तता युक्त विद्यार्थियों की शिक्षा एवं सामाजिक व आर्थिक रूप से पिछड़े (SEDGs) समूह की शिक्षा राष्ट्रीय शिक्षा नीति 2020 के केंद्र में है जिसके लिए आने वाले दिनों में समावेशी शिक्षा को बढ़ावा देना सरकार की महत्वपूर्ण प्राथमिकताओं में एक होगी। समावेशी शिक्षा की जड़ें सामाजिक भूमिका संवर्द्धन के सिद्धांत में हैं जो मानवीय सेवाओं से संबंधित एक व्यापक दिशा-निर्देश है। हालांकि विषय के विद्वानों में इस बात पर मतभेद है कि ‘यह एक आदर्शवादी विचारधारा है’ अथवा ‘मानवीय सेवाओं का दिशा निर्देश’ परंतु विद्वानों में इस बात पर मतैक्य है कि ‘सामाजिक भूमिका संवर्द्धन’ और इसकी पूर्ववर्ती विचारधारा ‘सामान्यीकरण’ की अवधारणा का दिव्यांग विद्यार्थियों की शिक्षा एवं दिव्यांगजनों के पुनर्वास संबंधी सेवाओं पर गहरा प्रभाव पड़ा है । कुछ विद्वान इसे समस्त समावेशी सेवाओं के विकास का मूल मानते हैं चाहे वह समेकन हो, समावेश हो, समावेशी शिक्षा हो या व्यावसायिक पुनर्वास हो, इन सभी जड़ें सामान्यीकरण एवं सामाजिक भूमिका संवर्द्धन के सिद्धांत में हैं। सामाजिक भूमिका संवर्द्धन की अवधारणा जिसकी जड़ें टालकोट पारसंस द्वारा दी गयी भूमिका सिद्धांत में है, उसे समावेशन अथवा समावेशी शिक्षा के मार्गदर्शक या दर्शन के रूप में देखा जा सकता है। सामाजिक भूमिका संवर्द्धन का सिद्धांत विचलित व्यवहार वाले सामाजिक अवमूल्यन के शिकार या उसके कगार पर स्थित व्यक्तियों अथवा समूहों की सामाजिक भूमिका को उनकी व्यक्तिगत क्षमता एवं उनका सामाजिक विम्ब उन्नत बनाकर उन्हें मूल्यवान सामाजिक भूमिकाओं में स्थापित करने की वकालत करता है ताकि उन्हें भी समाज में अच्छी चीजों की प्राप्ति हो एवं उनका सफल पुनर्वास हो सके एवं विद्यालयी तथा उच्च शिक्षा दोनों के स्तर पर समावेशी शिक्षा के राष्ट्रीय शिक्षा नीति 2020 के लक्ष्य को प्राप्त किया जा सके ।
ORAL HEALTH HYGIENE BEHAVIOR RELATE TO PRACTICES OF ORAL HEALTH: A CROSS-SECTIONAL STUDY
Authors: Vyas Harsh , Jani Kinjal G.
Published: February 2023

BACKGROUND: Oral health conditions i.e. dental caries and periodontal conditions are the leading oral ill-health conditions. To focus only on the curative and/or surgical aspects is not sufficient to reduce the oral health burden globally. The gap in oral health behavior is one of the prime reasons for the intricate oral health burden.
OBJECTIVES: This study aims to evaluate self reported practices toward oral health behavior among the adults of North Gujarat.
METHODS: The study was cross-sectional observational and conducted in the region of North Gujarat. A total of 150 adults were included in this study. A questionnaire that was predesigned and pretested was used to achieve the objective of the study. Statistical Package for Social Science (SPSS) version 24.2 was used by the researcher to analyze data.
RESULTS: in all adults who participated, the highest desirable practice was the usage of toothbrushes and toothpaste among 75.3% of adults, whereas the lowest was the scaling frequency which was 8% among the adults. The practice of Brush changing pattern, bristles of the brush, gargling with plain water, mouth wash usage, the direction of brushing, and the previous dentist visit was limited among the adults. The study found the socio-demographic variables as the predictors of oral health behavior.
CONCLUSION: the result highlights limited oral health behavior among adults. Desirable oral health habits and awareness of oral health need to be addressed. Coordination of efforts throughout healthcare along with proper social network reformation can play a significant role to uplift oral health behavior within the community.
Colonias, Water, and Extractable Bodies: COVID19’s impact on the Rio Grande Valley
Authors: Molina Hilario , Carly Robert
Published: February 2023

This paper develops the concept of “extractible bodies” and extends it to apply to Latinxs' experience in the Rio Grande Valley (RGV) subject to structural problems and predatory market practices before and during the pandemic. The RGV has had more COVID cases than counties of equal population size. Through a mixed-methods approach, this paper describes, in detail, how racist state practices, structural inadequacies, poor administration, and predatory capitalism effectively explain why the RGV was the epicenter of COVID-19 in the State of Texas in 2020. We introduce a concept, extractable bodies, to show how Mexican Americans provide limitless opportunities for exploitation while, at the same time, lacking basic public services and shouldering the blame for such circumstances. We focus our analysis on Latinx “essential workers” in an area challenged by health issues, high obesity rates, inadequate infrastructure, the situation in las colonias, and how these factors contributed to the COVID crisis. KEYWORDS: COVID 19, Latinxs, Mixed Methods, Health Disparity, Racism, South Texas
The People Jhumpa Lahiri Little Likes
Authors: Cussen John
Published: February 2023

This paper makes the claim that despite the culture-page and scholar classes' favorable reception of just about everything she offers, Bengali-American writer Jhumpa Lahiri thinks meanly of them and of their progressive mindsets. Telling in the second's regard are her counter-normative usages of their favored tropes--of, for example, the madwoman-in-the-attic trope. Telling in the first's regard are the literary academics who appear in her fictions. Nine for nine, they are shallow, feckless, and bullying sorts. Yes, literary academics--they are the people Jhumpa Lahiri little likes. In its later pages, the paper also observes that for much of her career writer Lahiri has been in the throes of a crisis of literary faith. An early symptom of this crisis is discernible in that plot strand of her second book, The Namesake, wherein the protagonist Gogol does everything in his power to dispossess himself of his literary name. Another symptom of the crisis is the sparsity of literary allusions that mark her fourth and latest fiction's pages (as opposed to the great number that marked her earlier works). And, lastly, toward the end of the latest fiction, Whereabouts, when the writing-prof protagonist begins her journey out of the city that has been her lifelong residence, that’s Lahiri wishing she could do the same vis á vis her literary faith. KEYWORDS: Jhumpa Lahiri, Critical Reception, Academic Culture, Immigrant Fiction
Leto Mission Concept for Green Reconnaissance of the Marius Hills Lunar Pit
Authors: Hooper Donald M. , Ximenes Samuel W. , Patrick Edward L. , Wells Ronald , Shaffer Allison , Necsoiu Marius
Published: February 2023

Lava tubes are potentially important sites for the long-term human presence on the Moon because they provide shelter from surface hazards, including micrometeorites, radiation, extreme temperatures, and dust. The discovery of a lava tube opening or pit at Marius Hills in Oceanus Procellarum is compelling motivation for robotic and eventually human exploration missions to these sites for in situ investigations and site assessments to determine viability for habitation and utilization of lunar resources. We make the case for Marius Hills to be a high-priority landing site and present elements of lunar data analysis, instrument/payload concepts, science justification for robotic missions, and thematic geologic reconnaissance and remote sensing that should be conducted prior to any construction or emplacement of infrastructure. This is described as a “green reconnaissance” approach to lunar exploration and exploitation, which seeks to address such contamination factors as sprayed rocket exhaust and sublimating water in order to preserve science fidelity. We are developing a concept of operations called the Leto mission for a green reconnaissance approach to robotically access the Marius Hills sublunarean void.
Genetic diversity among sea snakes of the genus Hydrophis (Elapidae, Reptilia) in the Persian Gulf and Gulf of Oman
Authors: Yousefkhani Seyyed Saeed Hosseinian , Yasser Amaal , Naser Murtada , Rezaie-Atagholipour Mohsen , Askari Hesni Majid , Yousefabadi Fariba , Rastegar-Pouyani Eskandar
Published: February 2023

The Persian Gulf and Gulf of Oman are two important marine ecosystems in southern Iran with rich biodiversity. Sea snakes of the genus Hydrophis are important components of the animal diversity in this area. Ten species of the genus Hydrophis have been distinguished in the region and their genetic structure was compared with other populations in south and southeast Asia.  We found that five species (including H. platurus, H. cyanocinctus, H. spiralis, H. schistosus and H. gracilis, H. lapemiodes) show high genetic similarity with conspecific populations in the Indian Ocean and Australia. Hydrophis curtus from southern Iran shows a high level of differentiation from other populations in Sri Lanka and Australia. Hydrophis curtus in our study shows variation and the Iranian samples of the species of 0.6% and 6% genetic distance from other populations in Sri Lanka for 16S and COI gene fragments, respectively. This means the variability between Iranian and southeast Asia populations may reveal new genetic lineages and the need of further morphological evaluations to re-evaluate their taxonomic position.
The identity of Argyria lacteella (Fabricius, 1794) (Lepidoptera, Pyraloidea, Crambinae), synonyms, and related species revealed by morphology and DNA capture in type specimens
Authors: Landry Bernard , Bilat Julia , Hayden James , Solis M. Alma , Lees David C. , Alvarez Nadir , Léger Théo , Gauthier Jérémy
Published: February 2023

In this study the aim was to resolve the taxonomy of several species ofArgyriaHübner (Pyraloidea, Crambinae) with previously unrecognised morphological variation. By analysing the DNA barcode (COI-5P) in numerous specimens, the aim was to reconstruct phylogenetic relationships between species, to provide better evidence for synonymies, and to circumscribe their geographical distribution. Using an innovative DNA hybridisation capture protocol, the DNA barcode of the lectotype ofArgyria lacteella(Fabricius, 1794) was partially recovered for comparison with the 229 DNA barcode sequences ofArgyriaspecimens available in the Barcode of Life Datasystems, and this firmly establishes the identity of the species. The same protocol was used for the following type specimens: theArgyria abronalis(Walker, 1859) holotype, thus confirming the synonymy of this name withA. lacteella, the holotype ofA. lusella(Zeller, 1863),syn. rev., the holotype ofA. multifactaDyar, 1914,syn. nov.newly synonymised withA. lacteella, and a specimen ofArgyria diplomochalisDyar, 1913, collected in 1992. In addition, nine specimens ofA. lacteella,A. diplomochalis,A. centrifugensDyar, 1914 andA. gonogrammaDyar, 1915, from North to South America were sampled using classical COI amplification and Sanger sequencing.Argyria gonogrammaDyar, described from Bermuda, is the name to be applied to the more widespread North American species formerly identified asA. lacteella. Following morphological study of its holotype,Argyria vestalisButler, 1878,syn. nov.is also synonymised withA. lacteella. The nameA. pusillalisHübner, 1818, is considered a nomen dubium associated withA. gonogramma. The adult morphology is diagnosed and illustrated, and distributions are plotted forA. lacteella,A. diplomochalis,A. centrifugens, andA. gonogrammabased on slightly more than 800 specimens. For the first time, DNA barcode sequences are provided for the AntilleanA. diplomochalis. This work provides a modified, improved protocol for the efficient hybrid capture enrichment of DNA barcodes from 18thand 19thcentury type specimens in order to solve taxonomic issues in Lepidoptera.
Netzwerke der Moderne als Kompositionsprinzip in Wolfgang Hilbigs Gedicht Der Schlaf in der Dämmerung (2001). Zwischen polyphoner Inspiration, memento mori und Gedenken
Authors: Lapchine Nadia
Published: February 2023

Le dernier recueil de Wolfgang Hilbig, Bilder vom Erzählen (2001), se caractérise par le dialogue programmatique avec le « Livre rêvé de la modernité » (« Traumbuch der Moderne ») qui trouve son expression notamment dans l’adhésion à une poétique intertextuelle. L’élaboration progressive d’un « langage universel de la poésie moderne » (« Weltsprache der modernen Poesie ») va de pair avec la création d’un réseau de figures tutélaires qui rassemble les grands représentants du symbolisme français et allemand. La métaphore récurrente du fil renvoie ainsi à la construction d’un réseau polyphonique au sein de l’espace mémoriel du recueil Bilder vom Erzählen . La lecture intertextuelle du poème Der Schlaf in der Dämmerung permettra de mettre en évidence l’intérêt herméneutique de la notion de réseau comme figure de l’interauctorialité et principe de composition poétologique.
The Token Woman of 1922? Virginia Woolf and the Gendered Battles of Anglo-American Modernist Criticism
Authors: Favre Valérie
Published: February 2023

Cet article propose d’explorer l’histoire de la réception de 1922 dans la critique littéraire anglo-américaine au prisme du genre, des années 1950 à la célébration de son centenaire. Il examine l’apparition du topos critique de l’« annus mirabilis », tout en retraçant l’inclusion progressive de Virginia Woolf aux côtés de T.S. Eliot et de James Joyce dans le canon de 1922, en tant que « femme alibi ». Il interroge ainsi la place des femmes dans l’année la plus emblématique du modernisme, ainsi que l’impact de la critique littéraire féministe sur l’histoire du modernisme et, plus particulièrement, sur « le genre de 1922 ». Enfin, il analyse les différentes fonctions de l’exceptionnalité woolfienne dans la construction du mythe de 1922, avant d’évoquer brièvement, en guise de conclusion, la réflexion que Woolf développe, dans Jacob’s Room , sur l’écriture de l’histoire, la célébration des « grands hommes » et l’invisibilisation des femmes dans la tradition et le canon littéraires.
Transcendance du visage et liberté du sujet. Éthique et politique phénoménologiques de la tolérance (Sartre, Levinas, Heidegger)
Authors: Vishnu Spaak Claude
Published: February 2023

La tolérance pose certaines questions essentielles aux analyses phénoménologiques de l’intersubjectivité. Tout d’abord, comme Sartre ou Heidegger l’avaient souligné, dans quelle mesure la tolérance ne se retourne-t‑elle pas toujours en une intolérance plus profonde, sous les formes de l’indifférence à l’égard de l’autre ou bien d’une domination qui réduit l’altérité d’autrui à des propriétés imposées, le privant de sa liberté ? Mais si l’on prend au contraire le parti de construire un concept positif de tolérance pour penser la relation éthique, alors le problème est de maintenir une double exigence : celle d’accueillir autrui en s’ouvrant à son altérité par rapport à moi, mais aussi celle de ne pas traiter cette altérité comme une différence abstraite. Il s’agit de reconnaître que la manifestation d’autrui est toujours située dans le monde, impliquant un ensemble de valeurs et de croyances susceptibles d’être en inadéquation avec les miennes, et qui doivent être supportées ou endurées malgré tout dans certaines limites sûrement impossibles à fixer a priori . Ainsi le phénomène de la tolérance demande que l’on envisage les normes absolues de la rationalité éthique comme toujours déjà particularisées dans des situations sociales concrètes, avec leurs caractéristiques politiques, culturelles, cultuelles et historiques contingentes. Nous montrons dans cet article que c’est précisément ce que Levinas (et Derrida à sa suite) comprend lorsqu’il aborde la question de l’intersubjectivité à partir du problème du tiers . La tolérance donne ainsi l’opportunité de penser les conditions du cosmopolitisme comme structure phénoménologique de la relation intersubjective (le rapport à l’autre comme rapport situé mondainement), même si l’on pourra alors se demander, en conclusion, si la tolérance abordée dans une perspective de l’émancipation, au sein d’une « histoire universelle d’un point de vue cosmopolitique », n’appartient pas à la vision philosophique des Modernes et de l’ Aufklärung , et si elle est encore tenable dans un monde de plus en plus dominé par l’essence de la technique.
Philosophie transcendantale et scepticisme. Kant au prisme de la querelle des arguments transcendantaux
Authors: Ehrsam Raphaël
Published: February 2023

Dans cet article, nous partons de la manière dont Strawson et Stroud ont interprété les rapports entre philosophie transcendantale et scepticisme. Contre leur lecture de Kant, nous soutenons que ce dernier ne vise pas de façon centrale à produire des preuves pour réfuter un scepticisme généralisé vis-à-vis de la connaissance et du monde extérieur. Nous défendons l’idée selon laquelle la structure des raisonnements transcendantaux kantiens court-circuite un tel scepticisme d’entrée de jeu plus qu’il n’en démontre la fausseté. En effet, pour Kant, l’effectivité de l’expérience objective et des connaissances scientifiques est une prémisse de la réflexion transcendantale, non une conclusion de celle-ci, et tout doute au sujet d’une telle prémisse serait à ses yeux oiseux plutôt que simplement erroné.
Investir en sécurité nuit-il à la santé financière de l’entreprise ?
Authors: Piluso Nicolas
Published: February 2023

Résumé − L’article tente d’analyser les effets d’un investissement de sécurisation du processus de production sur la dynamique des dividendes distribués. Il s’agit de répondre à la question de savoir si une industrie à risque a intérêt à investir dans la sécurité indépendamment de la baisse de la probabilité d’accident générée par la sécurisation. Bien qu’il existe une tension évidente entre sécurité et rentabilité, il apparaît que la firme peut, dans certains cas que nous identifions, avoir intérêt à investir dans la mesure où l’accumulation du capital et la distribution de dividendes ne sont pas durablement affectées par la sécurisation.
Les hospitalisations multiples du patient âgé ne sont plus une fatalité
Authors: Lanza Danièle , Séchaud Laurence , Jeune Violette , Pinault Françoise
Published: February 2023

Un renforcement des soins, visant à l’amélioration de leur qualité par l’application de quatre stratégies, à savoir : l’infirmière de référence, le processus de soins écrit, la formation-supervision par un clinicienne, la coordination de la communication entre partenaires, auprès de 167 personnes âgées hospitalisées à l’Hôpital de gériatrie de Genève (Suisse) met en évidence une diminution du nombre et de la fréquence de réhospitalisations chez les personnes ayant bénéficié de ces stratégies ainsi qu’une mobilisation accrue de leurs ressources personnelles pendant l’année où ils ont été suivis. Cette étude, réalisée en partenariat entre les « Institutions Universitaires de Gériatrie » et l’« École de soins infirmiers et de sages-femmes Le Bon Secours » à Genève, s’est déroulée sur deux ans de novembre 1990 à décembre 1992.
Implementation of Web-based Character Assessment on Students' Character Outcomes: A Review on Perception and Gender
Authors: Asrial Asrial , Syahrial Syahrial , Kurniawan Dwi Agus , Aldila Febri Tia , Iqbal Muhammad
Published: February 2023

This study aims to see the effect of students' perceptions on the results of character assessment using a gender-based web-based assessment. The population in this study was a junior high school in Batanghari Regency with a sample of 322 students using purposive sampling technique. Quantitative methods are used in this study with descriptive and inferential analysis methods to obtain assumption tests (normality, homogeneity, and linearity) and hypothesis testing (Anova and Linear Regression). The results of this study indicate that the perceptions of male and female students affect the results of character assessment, this is indicated by the results of a linear regression test with a significance value of 0.001 for both sexes. This is a supporting indicator in the implementation of web-based assessments apart from the real-time benefits and very fast feedback. Therefore, the application of web-based assessment to measure student character is good for use in learning which is indicated by good student perceptions of its application.
Effect of brain-based teaching strategy on students’ retention and self-efficacy in heat energy
Authors: Bada Abiodun , Jita Loyiso
Published: February 2023

Inequality in education is a challenge that have persisted and still likely to persist for a long time in the field of education because students come into the classroom with different characteristics. This situation pose a great threat to the realization of classroom objectives especially during physics lessons because students struggle to remember the concepts that have been learnt overtime. The use of adequate teaching strategy might break this limitation thus making every student to engage in meaning learning. This paper has two objectives; (i) to investigate the effect of brain-based teaching strategy on students’ retention in heat energy (ii) to investigate if self-efficacy influence physics students’ retention in heat energy when taught using brain-based teaching strategy. This investigation adopt the pre-test post-test control group quasi experimental design. It involved 99 (experimental group, n= 46; control group, n=53) students randomly selected from two schools in Ondo. A researcher designed instrument titled heat energy test (HET) was used to obtain data for this study. HET was validated by three science education experts and two secondary school physics teachers. The data collected were analysed using mean, t-test and analysis of covariance (ANCOVA). The findings from this study reveal that brain-based teaching strategy has significant effect on the retention of physics students in heat energy and self-efficacy did not influence physics students’ retention in heat energy. This paper concludes that brain-based teaching strategy enhances the retention of physics concepts thus breaking the limitation posed by differences in the characteristics of the students.
Differential drive kinematics and odometry for a mobile robot using TwinCAT
Authors: Ferreira Miguel , Moreira Luís , Lopes António
Published: February 2023

In this paper, we propose a motion control system for a low-cost differential drive mobile robot. The robotic platform is equipped with two driven wheels powered by Beckhoff motors, instrumented with incremental encoders. The control system is designed and implemented using Beckhoff's TwinCAT 3 automation software, running on an industrial PC. The system is tested and experimentally tuned to achieve optimal performance. The method allows addressing both odometry motion accuracy and motion correction in order to obtain minimum trajectory errors. Test results on linear and angular robot trajectories show errors below 0.02 and 0.03%, respectively, after tuning of the motion parameters. The proposed approach can be expanded, tweaked and applied to other differential drive TwinCAT 3 based robotic solutions. This will contribute to expanding mobile robot applications to a variety of fields, such as industrial automation, logistics, warehouse management, health care, ocean and space exploration and a variety of other industrial and non-industrial activities.
Note on complete convergence and complete moment convergence for negatively dependent random variables under sub-linear expectations
Authors: Xu Mingzhou , Kong Xuhang
Published: February 2023

In this article, we study the complete convergence and the complete moment convergence for negatively dependent (ND) random variables under sub-linear expectations. Under proper conditions of the moment of random variables, we establish the complete convergence and the complete moment convergence. As applications, we obtain the Marcinkiewcz-Zygmund type strong law of large numbers of ND random variables under sub-linear expectations. The results here generalize the corresponding ones in classic probability space to those under sub-linear expectations.
Fixed point approach to the Mittag-Leffler kernel-related fractional differential equations
Authors: Hammad Hasanen A. , Işık Hüseyin , Aydi Hassen , Sen Manuel De la
Published: February 2023

The goal of this paper is to present a new class of contraction mappings, so-called $ \eta _{\theta }^{\ell } $-contractions. Also, in the context of partially ordered metric spaces, some coupled fixed-point results for $ \eta _{\theta }^{\ell } $-contraction mappings are introduced. Furthermore, to support our results, two examples are provided. Finally, the theoretical results are applied to obtain the existence of solutions to coupled fractional differential equations with a Mittag-Leffler kernel.
Data augmentation based semi-supervised method to improve COVID-19 CT classification
Authors: Chen Xiangtao , Bai Yuting , Wang Peng , Luo Jiawei
Published: February 2023

The Coronavirus (COVID-19) outbreak of December 2019 has become a serious threat to people around the world, creating a health crisis that infected millions of lives, as well as destroying the global economy. Early detection and diagnosis are essential to prevent further transmission. The detection of COVID-19 computed tomography images is one of the important approaches to rapid diagnosis. Many different branches of deep learning methods have played an important role in this area, including transfer learning, contrastive learning, ensemble strategy, etc. However, these works require a large number of samples of expensive manual labels, so in order to save costs, scholars adopted semi-supervised learning that applies only a few labels to classify COVID-19 CT images. Nevertheless, the existing semi-supervised methods focus primarily on class imbalance and pseudo-label filtering rather than on pseudo-label generation. Accordingly, in this paper, we organized a semi-supervised classification framework based on data augmentation to classify the CT images of COVID-19. We revised the classic teacher-student framework and introduced the popular data augmentation method Mixup, which widened the distribution of high confidence to improve the accuracy of selected pseudo-labels and ultimately obtain a model with better performance. For the COVID-CT dataset, our method makes precision, F1 score, accuracy and specificity 21.04%, 12.95%, 17.13% and 38.29% higher than average values for other methods respectively, For the SARS-COV-2 dataset, these increases were 8.40%, 7.59%, 9.35% and 12.80% respectively. For the Harvard Dataverse dataset, growth was 17.64%, 18.89%, 19.81% and 20.20% respectively. The codes are available at https://github.com/YutingBai99/COVID-19-SSL.
Structurer, affirmer son identité : stratégies identitaires des fans LGBT de l’Eurovision au cours de la pandémie de Covid-19
Authors: Abbes Oranie
Published: February 2023

Le concours Eurovision de la chanson fait l’objet de critiques virulentes de la part des élites artistiques et intellectuelles. Pourtant, la défense des droits individuels et collectifs des minorités y apparaît comme un sujet particulièrement sensible. Couramment (re)baptisé de termes religieux tels que Pessah ou Noël « gay », cet événement est considéré comme une « expérience structurante » de l’identité des individus revendiquant une orientation sexuelle ou un genre différent. Récemment, le concours a été mis à mal par la pandémie de Covid-19. Dans ces conditions, l’article propose d’étudier les stratégies établies par les fans LGBT de l’Eurovision notamment via les réseaux sociaux, afin de poursuivre cette quête identitaire. Dans un premier temps, comment ce public constitue-t-il un contre-public subalterne se saisissant du concours afin de faire valoir un certain nombre de revendications en faveur des minorités sexuelles ? Dans un deuxième temps, en l’absence de concours, ce contre-public s’organise afin de développer de nouvelles stratégies identitaires, notamment en ligne ; nous tenterons de comprendre cette organisation. Enfin, nous nous intéresserons à la manière dont cette nouvelle organisation tend à faire persister, voire à accroître de nombreuses inégalités entre ces fans issus de la communauté LGBT.
Les agressions sexuelles dans les téléséries québécoises : une analyse des normes sexuelles et de genre contemporaines
Authors: Cousineau Amélie
Published: February 2023

L’objectif de cet article est d’analyser les représentations des agressions sexuelles contre les femmes dans les téléséries contemporaines au Québec, pour interroger les normes sexuelles et de genre qui y sont véhiculées. Une analyse thématique de données télévisuelles (tirées de Fugueuse, Les Simone et Le Monstre) a été faite, en mobilisant la théorie des scripts sexuels de William Simon et John Gagnon. L’article se demande : a) quels types de scripts sur les agressions sexuelles pouvons-nous observer dans les téléséries étudiées ? b) qu’est-ce que la présence (et la coexistence) de ces scripts nous apprend sur les normes sexuelles et de genre contemporaines ? Notre recherche a montré que certains scripts mobilisant des mythes (SM) n’apparaissent plus, alors que d’autres se prolongent et coexistent au sein d’un même récit avec des scripts s’éloignant des SM. Nous constatons ainsi dans notre échantillon la présence de récits alternatifs s’éloignant des histoires archétypales sur le viol, bien que cela n’implique pas nécessairement un changement de normes sexuelles et de genre. Cette coexistence de scripts pourrait être expliquée par l’ambivalence structurelle des téléséries, mais pourrait aussi constituer une brèche idéologique liée au contexte de revendications féministes des dernières années.
Vieillir hors couple : est-ce vieillir sans sexualité ?
Authors: Goetschy Maïlys , Berger Hoël , Benadouda Brahim , Dasré Aurélien , Pannetier Julie
Published: February 2023

La sexualité des célibataires de plus de 50 ans est encore rarement étudiée en raison d’un double angle mort de la recherche : le célibat et la sexualité des personnes plus âgées. Les grandes enquêtes sur la sexualité en France ont bien montré que malgré une diminution de la fréquence des rapports sexuels au cours de la vie, neuf personnes en couple sur dix ont toujours des relations sexuelles passé 50 ans. En revanche, la sexualité des célibataires dans leur cinquantaine, soixantaine et au-delà reste, quant à elle, à interroger. À partir des données du Baromètre Santé 2016, cet article propose une analyse de la sexualité des célibataires de plus de 50 ans selon le genre, l’âge, la catégorie socioprofessionnelle et l’orientation sexuelle. La sexualité des plus de 50 ans en dehors du couple est relativement fréquente bien que différenciée selon le genre : une femme sur trois a eu au moins un rapport sexuel dans l’année contre deux hommes sur trois. Cette différence s’accroît avec l’avancée en âge et la position plus élevée dans la hiérarchie sociale. De plus, les hommes bisexuels ou homosexuels célibataires maintiennent plus souvent une vie sexuelle passé 50 ans que les hommes exclusivement hétérosexuels.
Audit on lipid screening, management and target achievement in prevention of cardiovascular disease in patients attending a medical clinic in National Hospital Kandy: Are we on par with the guidelines?
Authors: Nasim F. N. , Jazeema M. , Fasrina F. , Bowattage S. , Kularatne W. K. S.
Published: February 2023

Background: Cardiovascular disease (CVD) remains a major cause of morbidity and mortality in Sri Lanka. 2019 European Society of Cardiology (ESC) guidelines recommend risk stratification based on co- morbidities, lipid profiles, standardized scoring and prescription of statins to achieve set lipid targets, to reduce CVD. Nevertheless implementation of guidance remains variable. The objective of this study was to identify the gaps in clinical practice and adherence to ESC guidelines in the management of dyslipidaemia.
Methods: All patients attending a routine internal medical clinic were assessed retrospectively. Their comorbidities, level of risk, current therapy, cholesterol monitoring, and response to LDL-C targets were noted and compared with guideline based audit standards.
Results: Out of 114 patients (69 female) with a mean age (±SD) of 63.98 (±11.5) years, 39 (34.2%) had CVD, 18 (15.8%) strokes, 70 (61.4%) hypertension and 63 ( 43.8 %) type 2 diabetes mellitus. Only 55.3% of patients had a single lipid profile and 39.7% a subsequent measurement. While 56.4% of CVD and 38.8% of stroke patients were on moderate intensity statins, 38.4% of CVD and 44.4% of stroke patients were on high intensity statins. Despite lack of contraindications 5.1% of CVD and 16.6%of stroke patients were not on satins. Of the patients with diabetes, 22%were not on statins and 68% were on low or moderate intensity statins. Lipid targets were achieved in 23.8% of the patients with diabetes. Targets were not checked in the majority. Of the 56% who didn’t achieve targets only 41.1% received drug optimisation.
Conclusions: Lipid screening and treatment targets remain suboptimal despite set guideline standards. Dissemination of guideline recommendations and motivation to reduce physician inertia is mandatory in preventing cardiovascular disease.
Are low-and-middle-income countries using scarce resources effectively to tackle noncommunicable diseases in the pandemic era?
Authors: Mendis S.
Published: February 2023

The noncommunicable disease (NCD) burden continues to grow and is a major threat to socioeconomic development, particularly in low-and-middle-income countries. The COVID-19 pandemic has had a significant negative impact on the prevention and control of NCDs. Pre-existing challenges to the prevention and control of NCDs, including financial and health workforce limitations, have been further intensified by the COVID -pandemic. Despite these barriers, accelerating action to address NCDs is imperative to reduce premature mortality and escalating healthcare costs. In the post-pandemic context, a strong focus on cost and sustainability considerations is essential for making progress on reducing premature mortality by one-third by 2030: Sustainable Development Goal target 3.4. Low and middle income countries (LMIC) can succeed only by prioritizing the implementation and national scale-up of at least 16 very cost-effective NCD interventions. Among them are population-wide policy interventions which address tobacco, harmful use of alcohol, physical inactivity and unhealthy diet. The only health system intervention affordable to all LMICs embraces the total risk approach to tackle hypertension, diabetes, hypercholesterolemia, smoking and overweight in an integrated manner in a primary health care pathway. The burden of sustainability calls for the inclusion of best buy interventions as integral components of the basic benefits package of Universal Health Coverage initiatives.
RIAM regulates myeloid cell fate commitment and macrophage polarization and controls tumor progression
Authors: Christofides Anthos , Cao Carol , Pal Rinku , Boussiotis Vassiliki A
Published: February 2023

Initiation of immune responses requires integrin-mediated adhesion between T cells and APC, linking innate and adaptive immunity. Integrins also regulate leukocyte trafficking and extravagation at sites of inflammation. Among the few molecules implicated in integrin activation is the Rap1-interacting molecule (RIAM). Tumor-driven emergency myelopoiesis induces expansion of myeloid progenitors and output of immature, immunosuppressive myeloid derived suppressor cells (MDSC), and tumor-associated macrophages (TAM). TAMs are classified into two groups: M1, which have a pro-inflammatory and anti-tumor function and M2, which have an anti-inflammatory role and facilitate tumor progression. To determine whether RIAM affects the properties of myeloid cells and tumor progression, we generated mice with conditional targeting of RIAM and crossed them with LysMCre mice (RIAMfl/flLysMCre) to delete RIAM specifically in the myeloid compartment. Using the B16-F10 melanoma and MC17-51 fibrosarcoma tumor models, we determined that RIAMfl/flLysMCre mice displayed an accelerated growth and significantly larger tumors compared to RIAMfl/fcontrol mice. There were no numerical differences in CD11b+F4/80+ macrophages, CD11b+Ly6ChiLy6G− monocytic (M-MDSC), CD11b+Ly6CloLy6G+ polymorphonuclear (PMN-MDSC) or CD11c+MHCII+ dendritic cells between the two groups. However, TAMs and splenic macrophages of RIAMfl/flLysMCre mice exhibited an M2-like phenotype. Bone marrow derived macrophages from RIAMfl/flLysMCre had an imprinted M2 polarization program. Thus, RIAM has a previously unidentified role in myeloid cell fate commitment that regulates macrophage polarization and controls tumor progression.
Genetically Engineered Myeloid Cells Rebalance the Core Regulatory Immune Suppression Program in Metastasis
Authors: Kaczanowska Sabina , Beury Daniel W , Qin Haiying , Kaplan Rosandra
Published: February 2023

Tumor metastasis is a critical step in the progression of solid tumors that is associated with patient mortality, yet we have limited knowledge of the metastatic microenvironment to effectively target this process. The pre-metastatic niche is the tumor-promoting microenvironment that is established at distant sites in response to primary tumor growth before detectable metastatic disease. We characterized immune populations in the lungs of tumor-bearing mice by flow cytometry and RNA sequencing approaches. We identified an immune suppression gene signature in pre-metastatic niche formation that is found predominantly within myeloid cells. In addition to the increase of myeloid cells and immunosuppressive pathways, we discovered that T cell populations are reduced in pre-metastatic lungs. We hypothesized that reversing this immunosuppressive environment would restore T cell function and antitumor immunity. We designed a novel approach in which we generated Genetically-Engineered Myeloid cells (GEMys) to deliver IL-12, a potent antitumor molecule, into the pre-metastatic microenvironment. We evaluated the lungs by flow cytometry and observed that IL12-GEMy-treated mice had increased numbers of T cells and enhanced expression of activation markers, resulting in reduced metastasis and increased survival. When combined with chemotherapy pre-conditioning, IL12-GEMys cured mice of established tumors and generated long-lived T cell memory, as these mice were immune to subsequent tumor challenge. These studies demonstrate that IL12-GEMys can functionally modulate the core program of immune suppression in the pre-metastatic niche to successfully rebalance the dysregulated metastatic microenvironment in cancer.
Induction of hyperresponsivity to LPS by Porphyromonas gingivalis in gingival epithelium
Authors: Gasiorek Anna , Dobosz Ewelina , Ciaston Izabela , Potempa Jan , Koziel Joanna
Published: February 2023

Chronic periodontitis (CP) is an inflammatory disease of the tooth supporting tissue developed in response to formation of the dysbiotic biofilm on the subgingival tooth surface. Although exacerbated inflammation leads to the alveolar bone destruction and may cause tooth loss the molecular basis of CP initiation and progression remains elusive. The control over the inflammatory reaction and homeostasis can be efficiently restored by the negative regulators of TLRs signaling pathways, such as MCPIP-1, which is constitutively expressed in gingival keratinocytes and prevents the hyporesponsiveness in the gum. Here we found that inflammophilic periodontal species influence stability of MCPIP-1 leading to aggravated response of the epithelium to proinflammatory stimulation. We identified that among enzymes secreted by those pathogenic species, gingipains – cysteine proteases from Porphyromonas gingivalis play a crucial role. Their proteolytic activity leads to a rapid degradation of MCPIP-1 exacerbating inflammatory response induced by endotoxin. Taken together, we showed the novel mechanism of corruption of inflammatory signaling by periodontal pathogens indicating new possibilities for treatment of this chronic disease.
CARD8 is an inflammasome sensor for HIV-1 protease activity
Authors: Shan Liang , Wang Qiankun
Published: February 2023

Human immunodeficiency virus type 1 (HIV-1) has high mutation rates and exists as mutant swarms within the host. The adaptive immune system recognizes cognate epitopes based on amino acid sequences and associated conformations that are subject to mutation. The within-host diversity of HIV-1 allows rapid selection of antibody and T cell escape variants, leading to viral persistence. Approaches to target immutable components are needed to clear HIV-1 infection. Here, we report that the CARD8 inflammasome senses HIV-1 protease activity. HIV-1 can evade CARD8 sensing because its protease remains inactive in infected cells prior to viral budding. Induction of premature intracellular activation of the viral protease triggers CARD8 inflammasome-mediated pyroptosis of HIV-1-infected cells. The viral protease activity against CARD8 is well conserved across major HIV-1 subtypes. This strategy led to the clearance of latent HIV-1 in patient CD4+ T cells after viral reactivation. Taken together, our study identifies CARD8 as an inflammasome sensor of HIV-1 that holds promise as a strategy for clearance of persistent HIV-1 infection.
Contribution of soluble ORF2 viral protein to viral replication and host immune response during acute Hepatitis E virus infection
Authors: Ralfs Philipp , Salinas Eduardo , Ambardekar Charuta , Bremer Bill , Blasczyk Heather , Zhu Jingting , Holland Brantley , Walker Christopher M , Feng Zongdi , Grakoui Arash
Published: February 2023

The hepatitis E virus (HEV) is a small, positive-stranded RNA virus that is a major cause of acute viral hepatitis globally. Acute HEV infection is typically asymptomatic and resolves within 8–10 weeks. HEV encodes 2 forms of capsid protein. A cytoplasmic form (ORF2c) is essential for virion structure. A secreted glycosylated form (ORF2s) accumulates at high titer in serum and can mask anti-ORF2 neutralizing antibodies. Here, we explored the contribution of ORF2s to HEV replicative fitness in vivo, and its role in generating anti-ORF2 antibodies (Abs). Rhesus Macaques (RM) were challenged by direct hepatic injection of infectious ORF2s+ and ORF2s− RNA. The replication of an HEV mutant lacking ORF2s expression was delayed by ~2 weeks when compared with wildtype virus and peak titers were nearly 10-fold lower for ORF2s−. No reversion of the 3 ORF2s silencing mutations was detected in the ORF2s− genomes, indicating genetic stability. The delay in replication and lower peak titer was unexpected as the viruses replicate similarly in cell culture. In addition, our data demonstrated that ORF2s has a significant and unexpected impact on generation of antibodies. Specifically, serum anti-ORF2 antibodies were only transiently detected in ORF2s− infected RM. As expected, anti-ORF2 titers were high and sustained in ORF2s+ infected RM. Furthermore, anti-ORF2 Ab response primed by ORF2s− infection differed in protection against reinfection when compared to ORF2s+. The ORF2s− challenged animals were re-infected upon second exposure to HEV infection. These findings indicate ORF2s may be dispensable for viral replication in vivo but is required for long-lived antibody response to mediate protection against re-exposure.