bluuebunny/crossref_metadata_2025 huggingface dataset:
Orman Endüstri Mühendisliği Eğitiminin Değerlendirilmesi
Authors:   İstanbul Üniversitesi-Cerrahpaşa Orman Fakültesi Orman Endüstri Mühendisliği Bölümü, Odun Mekaniği ve Teknolojisi Ana Bilim Dalı, İstanbul, Türkiye, Köse Coşkun , Dündar Türker ,   İstanbul Üniversitesi-Cerrahpaşa Orman Fakültesi Orman Endüstri Mühendisliği Bölümü, Odun Mekaniği ve Teknolojisi Ana Bilim Dalı, İstanbul, Türkiye
Published: January 2025

Türkiye’de 166 yıllık bir geçmişe sahip ormancılık eğitimi birikimi bulunmaktadır. 1857 yılında İstanbul’da Fransız Ormancı M. Louis Tassy’nin önderliğinde bir Orman Mektebinin açılması ile başlayan ormancılık eğitimi Cumhuriyet döneminde Orman Mektebi Âlisinin 1934 yılında
çıkarılan 2525 sayılı Kanun ile kaldırılması ve Orman Fakültesi haline dönüştürülerek Ankara
Yüksek Ziraat Enstitüsüne (AYZE) bağlanmasıyla sürmüştür. AYZE Orman Fakültesi bünyesinde
oluşturulan, Almanya’dan getirilen tanınmış bilim insanlarının yöneticiliğine getirildiği ilk beş
enstitüden biri Orman Mahsullerini Değerlendirme Enstitüsüdür. 1961 yılında enstitünün ikiye ayrılması sonucu oluşan Orman Mahsulleri Kimyası Enstitüsü ile birlikte Orman Mahsullerini Değerlendirme Enstitüsü ülkemizde ikinci orman fakültesinin eğitime başlamasına dek
orman ürünleri endüstrisiyle ilgili eğitim ve araştırma faaliyetlerini gerçekleştiren tek sorumlu
birimler olarak tarihe geçmişlerdir. Türkiye’nin ikinci Orman Fakültesi olarak 1963 yılında kurulan Karadeniz Teknik Üniversitesi Orman Fakültesi Orman Ürünleri Sanayi Mühendisliği Bölümü1971-1972 eğitim-öğretim yılında ilk öğrencilerine kavuşmuştur. İstanbul Üniversitesi Orman
Fakültesi (İÜOF) bünyesinde 1982 yılında başlayan Orman Endüstri Mühendisliği (OEM) lisans
eğitimi, 2018 yılında çıkarılan 7141 sayılı yükseköğretim kanunu ile birlikte İstanbul Üniversitesi-Cerrahpaşa Orman Fakültesi (İÜCOF) bünyesinde sürdürülmektedir. Türkiye’de 2023 yılı
itibariyle 12 orman fakültesi bulunmakla birlikte OEM lisans eğitimi 9 faklı üniversitede sürdürülmektedir. İÜCOF OEM lisans programı 2014 yılından itibaren Mühendislik Eğitim Programları
Değerlendirme ve Akreditasyon Derneği (MÜDEK) tarafından verilen mühendislik akreditasyonu
belgesine ve EUR-ACE etiketine sahiptir. Türkiye’de eşdeğer lisans programları arasında akredite olan ilk OEM lisans programıdır. İÜC OEM lisans programının eğitim dili 2015 yılından itibaren
%30 İngilizce’dir. 1982 yılında itibaren 2219 mezun verilmiştir. İÜOF’de OEM alanında lisansüstü
eğitim Fen Bilimleri Enstitüsünde 1986-1987 öğretim yılından itibaren başlamıştır. İÜOF’de OEM
alanında lisansüstü eğitim 2018 yılında çıkarılan 7141 sayılı Yükseköğretim Kanunu ile birlikte
İÜC Lisansüstü Eğitim Enstitüsü bünyesinde sürdürülmektedir. Bugüne kadar 107 adet yüksek
lisans tezi ve 53 adet doktora tezi tamamlanmıştır. Devam eden 7 adet yüksek lisans tezi ve 20
adet doktora tezi bulunmaktadır. İÜOF’de OEM alanında Fen Bilimleri Entitüsünde 1986-1987
eğitim öğretim yılında başlayan lisansüstü eğitim halen İÜC Lisansüstü Eğitim Enstitüsü bünyesinde sürdürülmektedir.
Cumhuriyet Dönemi Yapısal Peyzaj Üretimine İlişkin Paradigmalar
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Orman Fakültesi Peyzaj Mimarlığı Bölümü Peyzaj Teknikleri Ana Bilim Dalı, İstanbul, Türkiye, Çağlayan Ayça Yeşim
Published: January 2025

Teknolojik, ekonomik, politik ve toplumsal ortam koşullarındaki değişim, kendisini en belirgin
mekânsal düzenleme yaklaşımlarında göstermektedir. Tasarım yaklaşımlarını şekillendiren bu
değişim kimi zaman farklılaşan fikirsel ortam gibi yavaş ilerleyen çizgisel bir yapı sergilerken
bazen de savaş gibi, yıkıcı ve güçlü bir olayın etkisiyle sıçramalar şeklinde yaşanabilmektedir.
Sonuçta tasarım yaklaşımında ortaya çıkan dönüşüm, kavramlarla temsil edilebilecek kadar
dikkate değer olabilmektedir. Tarihinde tarımsal üretim ile doğayı, yaşantısının odağında deneyimleyen kadim uygarlıklar için beşik olan Anadolu’da, İslamiyet’le değişen bahçe anlayışı uzun
dönem etkisini göstermiş, çoğu zaman da ön plana çıkmıştır. Sıkı siyasi ve ticari ilişkiler kurulan Avrupa’da ortaya çıkan rasyonalist düşünce tasarım ve uygulama anlayışındaki değişimin
mihenk taşlarından biri olmuştur. Bilimsel yaklaşım sonrasında gelişen teknolojinin sağladığı
olanaklarla gerçekleştirilen topografik müdahaleler, farklı malzeme ve uygulama yöntemlerinin
kullanımı vb. eylemler, doğa insan arasındaki etkileşimi farklı bir boyuta taşımıştır. Ülke politikaları ile şekillenen toplumsal yapının ihtiyaç duyduğu mekânlar için kültürel peyzaj araştırmalarına çekilen dikkat, kentsel boşlukların kamusal alan kavramıyla gündeme getirilmesi gibi
dinamikler ülkemiz için de peyzaj planlama, tasarım ve uygulama yaklaşımlarını şekillendiren
etkenler olmuştur.
Diğer taraftan ilerleyen modern teknoloji ile gelişen yapı sektöründeki uygulama olanakları ve
disiplinler arası çalışmayı gerektiren bütüncül yaklaşım anlayışı, arazi kavramını gelenekselden
farklı bir bağlama taşımıştır. Tüm yaşanan ilerlemelere rağmen artan nüfus, alınan planlama
kararları, değişen yaşam şekilleri gibi nedenlerle yaşanan çevre sorunları, günümüzde önemini
iyice arttırmış, çözüme yönelik tasarım ve uygulama yaklaşımlarının da odağı haline gelmiştir.
Çalışmada günümüz yapısal peyzaj üretimini oluşturan tarihsel süreç, Cumhuriyet öncesi ve
Cumhuriyet dönemi tasarım anlayışı açısından incelenmiş, değişen ortam koşullarının peyzaj
pratiğine etkisi irdelenmiştir
Blockchain Technology, Regulatory Environment and Competitive Edge in Renewable Energy Sector in Kenya: A Systematic Literature Review
Authors: Brian wakasala
Published: January 2025

Abstract: This systematic review of literature bears the objective of exploring the potential of transformative novel blockchain technology, its regulation, and the substantive impact it bears on renewable energy firms' competitive advantage. The study provides a minutiae of the current trends in research, their implications, and blockchain implementation and innovation between 2019 to 2024. The methodology comprised a comprehensive search of scholarly databases, selection, and analysis of the relevant research studies. The findings revealed that Blockchain is essential based on its transparency, traceability, data privacy, and decentralization features which enhance trust, transparency, and traceability across the supply chain. Furthermore, blockchain technology is relevant in the renewable energy sector in Kenya ranging from p2p trading platforms, digitization by IoT, E-mobility, and decentralized trading platforms. The distributed ledger technology is a promising disruption for a wide area of service and product management in the energy sector ranging from the producers, transmitters, regulators, and distributors involved. The review concludes with future research recommendations and the practical implications for the industry players and the regulators.
Advances in Blockchain Solutions for Secure and Efficient Cross-Border Payment Systems
Authors: Eyo-Udo Nsisong Louis , Agho Mercy Odochi , Onukwulu Ekene Cynthia , Sule Aumbur Kwaghter , Azubuike Chima
Published: January 2025

The increasing demand for secure, efficient, and transparent cross-border payment systems has propelled the adoption of blockchain technology as a transformative solution. Blockchain, with its decentralized and immutable ledger capabilities, offers unparalleled advantages in streamlining international transactions by reducing intermediaries, lowering costs, and enhancing transaction speed. This paper explores recent advancements in blockchain-based cross-border payment systems, focusing on their potential to address the inefficiencies of traditional payment networks. Key developments include the integration of smart contracts for automated settlements, tokenization for currency interoperability, and enhanced security protocols to mitigate risks of fraud and cyberattacks. Blockchain’s ability to provide real-time transaction tracking and auditability fosters transparency and trust among financial institutions, regulators, and consumers. These features align with global demands for compliance and accountability in international payments. Furthermore, blockchain solutions are increasingly leveraging innovations such as layer-two scaling mechanisms, consensus algorithm improvements, and integration with artificial intelligence (AI) to address scalability and energy consumption challenges. These advancements are critical in ensuring blockchain’s viability for handling the growing volume of global financial transactions. The paper also examines the collaborative efforts of financial institutions, fintech companies, and governments in establishing blockchain-based payment ecosystems, such as RippleNet and the Stellar Network. These initiatives demonstrate the feasibility of blockchain in creating inclusive financial networks, particularly in underbanked regions, by enabling faster and cost-effective remittance services. While the potential of blockchain in cross-border payments is vast, challenges such as regulatory uncertainty, interoperability of blockchain platforms, and adoption resistance persist. Addressing these barriers will require unified international frameworks, technological standardization, and continued innovation. This paper highlights the transformative role of blockchain in redefining cross-border payment systems, underscoring its importance in achieving a secure, efficient, and inclusive global financial ecosystem.
Severity Weighting of Quality-Adjusted Life-Years for Economic Evaluation: What, How, and Where Next?
Authors: Ali Shehzad , Haines Alexander , Lee Karen
Published: January 2025

Some health technology assessment (HTA) agencies incorporate severity weighting in health economic evaluations to prioritize interventions for severe diseases. Measures like absolute and proportional shortfall are used to quantify disease severity; decision modifiers are then applied to increase the value of quality-adjusted life-year gains for severe conditions.
This paper reviews studies that measure societal preferences for prioritizing severity, as well as current methods used by HTA agencies to incorporate severity weighting into economic evaluations.
The review of the literature highlights preferences to reduce unfair health variations, with most studies indicating a willingness to prioritize the severely ill. A review of approaches conducted by HTA agencies found variation in how severity weighting was incorporated and valued. 
Further research is needed to better understand societal values regarding severity and the appropriate weighting of disease severity for economic evaluations within Canada.
A new portable sampler of atmospheric methane for radiocarbon measurements
Authors: Zazzeri Giulia , Wacker Lukas , Haghipour Negar , Gautschi Philip , Laemmel Thomas , Szidat Sönke , Graven Heather
Published: January 2025

Abstract. Radiocarbon (14C) is an optimal tracer of methane emissions, as 14C measurements enable distinguishing between fossil methane and biogenic methane (CH4). However, 14C measurements in atmospheric methane are still rare, mainly because of the technical challenge of collecting enough carbon for 14C analysis from ambient air samples. In this study, we address this challenge by advancing the system in Zazzeri et al. (2021) into a much more compact and portable sampler and by coupling the sampler with the MICADAS (MIni CArbon DAting System) accelerator mass spectrometry (AMS) system at ETH Zurich, using a gas interface. Here, we present the new sampler setup, the assessment of the system contamination and a first inter-laboratory comparison with LARA (Laboratory for the Analysis of Radiocarbon with AMS) at the University of Bern. With our sampling line, we achieved a very low blank, 0.7 µgC compared to 5.5 µgC in Zazzeri et al. (2021), and a sample precision of 0.9 %, comparable with other measurement techniques for 14CH4, while reducing the sample size to 60 L of air. We show that this technique, with further improvements, will enable routine 14CH4 measurements in the field for an improved understanding of CH4 sources.
Assessment of horizontally-oriented ice crystals with a combination of multiangle polarization lidar and cloud Doppler radar
Authors: Wu Zhaolong , Seifert Patric , He Yun , Baars Holger , Li Haoran , Jimenez Cristofer , Li Chengcai , Ansmann Albert
Published: January 2025

Abstract. The orientation of ice crystals plays a significant role in determining their radiative and precipitating effects, horizontally oriented ice crystals (HOICs) reflect up to ~40 % more short-wave radiation back to space than randomly oriented ice crystals (ROICs). This study for the first time introduces an automatic pixel-by-pixel algorithm for HOIC identification using a combination of ground-based zenith- and 15-degree off-zenith-pointing polarization lidars. The lidar observations provided high-resolution cloud phase information. The data were collected in Beijing over 354 days in 2022. A case study from 13 October 2022 is presented to demonstrate the effectiveness and the feasibility of the detection method. The synergy of lidars and collocated Ka-band cloud radar, radiosonde, and ERA5 data provide phenomenological insights into HOIC events. While cloud radar Doppler velocity data allowed the estimation of ice crystal size, Reynolds numbers, and turbulent eddy dissipation rates, corresponding environmental and radar-detected variables are also provided. HOICs were present accompanying with weak horizontal wind of 0–20 m s−1 and relatively high temperature between -8 ℃ to -22 ℃. Compared to the ROICs, HOICs exhibited larger reflectivity, spectral width, turbulent eddy dissipation rate, and a median Doppler velocity of about 0.8 m s−1. Ice crystal diameter (1029 μm to 1756 μm for 5th and 95th percentiles) and Reynolds numbers (28 to 88 for 5th and 95th percentiles) are also estimated with the help of cloud radar Doppler velocity using an aerodynamic model. One interesting finding is that the previously found switch-off region of the specular reflection in the region of cloud base shows a higher turbulence eddy dissipation rate, probably caused by the latent heat released due to the sublimation of ice crystals in cloud-base region. The newly derived properties of HOICs have the potential to aid to derive the likelihood of their occurrence in output from general circulation models (GCMs) of the atmosphere.
South Asia ammonia emission inversion through assimilating IASI observations
Authors: Xia Ji , Zhou Yi , Fang Li , Qi Yingfei , Li Dehao , Liao Hong , Jin Jianbing
Published: January 2025

Abstract. Ammonia has attracted signiﬁcant attention due to its pivotal role in the ecosystem and its contribution to the formation of secondary aerosols. Developing an accurate ammonia emission inventory is crucial for simulating atmospheric ammonia levels and quantifying its impacts. However, current inventories are typically constructed in the bottom-up approach and are associated with substantial uncertainties. To address this issue, assimilating observations from satellite instruments for top-down emission inversion has emerged as an effective strategy for optimizing emission inventories. Despite the severity of ammonia pollution in South Asia, research in this context remains very limited. This study aims to estimate ammonia emissions in this region by integrating the prior emission inventory from the Community Emissions Data System (CEDS) and the columned ammonia concentration retrievals from the Infrared Atmospheric Sounder Interferometer (IASI). We employ a newly-developed four-dimensional ensemble variational (4DEnVar)-based emission inversion system to conduct the calculations, resulting in monthly ammonia emissions for 2019 at a resolution of 0.5° × 0.625°. Our simulations, driven by the posterior emission inventory, demonstrate superior performance compared to those driven by the prior emission inventory. This is validated through comparisons against the IASI observations, the independent column concentration measurements from the advanced satellite instrument Crosstrack Infrared Sounder (CrIS), and the ground concentration observations of ammonia and PM2.5. Additionally, the spatial and temporal characteristics of ammonia emissions in South Asia based on the posterior are analyzed. Notably, emissions there exhibit a "double-peak" seasonal proﬁle, with the maximum in July and the secondary peak in May. This differs from the "double-peak" trend suggested by the CEDS prior inventory, which identiﬁes the maximum in May and a second peak in September.
Global Acritarch Database (>110 000 occurrences)
Authors: Shu Xiang , Song Haijun , Lei Yong , Chu Daoliang , Dal Corso Jacopo , Liu Xiaokang , Song Hanchen , Wei Lai , Jia Enhao , Feng Yan , Du Yong , Song Huyue , Yu Wenchao , Liang Qingzhong , Li Xinchuan , Yao Hong , Wu Yuyang
Published: January 2025

Abstract. Acritarchs, microfossils with an algal affinity, are of great significance for studying the origin and evolution of early life on Earth. Acritarch data are currently dispersed across various research institutions and databases worldwide, lacking unified integration and standardization. Palynodata was the largest database of acritarchs, containing 15 fields, 111 382 entries, 812 238 metadata items, and 7385 references. However, it lacked references post-2007 and excluded geographic data. Here, we collected and organized previous data, adding 24 fields, 4531 entries, 1 882 081 metadata points, and 424 references, to build a new global acritarch database. The expanded database now contains a total of 39 fields, covering genera, species, and related geological information (geological timescale, location, modern latitude and longitude, paleolatitude and paleolongitude, stratum, and others), amounting to 115 947 entries, 2 694 671 metadata, and 7816 references. Each entry is associated with fields that facilitate a better understanding of the geographical distribution and changes over geological timescales of acritarchs, thereby revealing their temporal and spatial distribution patterns and evolution throughout the history of the Earth. This article describes GAD version 1.0, which is available at https://doi.org/10.5281/zenodo.13828633 (Shu et al., 2024).
What is climate change doing in Himalaya? Thirty years of the Pyramid Meteorological Network (Nepal)
Authors: Salerno Franco , Guyennon Nicolas , Colombo Nicola , Melis Maria Teresa , Dessì Francesco Gabriele , Verza Gianpietro , Bista Kaji , Sheharyar Ahmad , Tartari Gianni
Published: January 2025

Abstract. Climate change is deeply impacting mountain areas around the globe, especially in Himalaya. However, the lack of long-term meteorological observations at high elevations poses significant challenges to understand and predict impacts at various scales. This also represents a serious limit for model-based projections of future behavior of crucial elements of the mountain cryosphere such as glaciers. Here, we present the Pyramid Meteorological Network, located in Himalaya (Nepal), on the southern slopes of Mt. Everest. The network is composed of 7 meteorological stations located between 2660 and 7986 m a.s.l., which have collected continuous climatic data during the last 30 years (1994–2023). In this paper, details are provided regarding instrument types and characteristics as well as data quality control and assessment. The obtained data series are available on a newly created geoportal. We leverage these unique records to present new knowledge on the Himalayan climate, benefiting also from the highest observational climatic series in the world (Pyramid station, located at above 5000 m a.s.l., close to Khumbu Glacier). These data will provide fundamental knowledge on climate dynamics in Himalaya that will inform research at high elevations in the coming years. The dataset is available freely accessible from https://geoportal.mountaingenius.org/portal/ (https://zenodo.org/records/14450214) (Salerno et al., 2024).
Jeanne-Marie Leprince de Beaumont face à la censure en Espagne
Authors: Onandia Ruiz Beatriz
Published: January 2025

Le XVIIIe siècle espagnol est une période très riche en traductions, portant notamment sur des textes pédagogiques français destinés à l’instruction des femmes des Lumières. Ce renouveau féminin fut particulièrement visible dans certaines traductions d’oeuvres pédagogiques françaises écrites par des plumes féminines, et notamment dans celle de Jeanne-Marie Leprince de Beaumont, pédagogue française qui, grâce aux traductions, connut une grande notoriété dans l’Espagne de l’époque. En étudiant les censures d’alors, cet article met en lumière le monde de la traduction espagnole au XVIIIe siècle, les mécanismes de la censure, les censures, les autocensures, les traductions publiées ou encore les adaptations. Dans un siècle où l’intervention ecclésiastique en matière de production et de diffusion de livres était assez évidente, la censure constitua un système ancien et organisé de dissuasion et de répression auquel l’Église fit constamment recours.
Traduire le français en français dans l’audiovisuel : le multilinguisme dans le doublage d’Emily in Paris
Authors: Reverter Oliver Beatriz
Published: January 2025

Cet article présente une étude visant à décrire les stratégies de traduction adoptées pour la version doublée en français des fragments multilingues avec une présence du français dans Emily in Paris. Les résultats montrent que les problèmes de traduction et les solutions ont tendance à se répéter tout au long de la série. Ainsi, quatre stratégies de traduction principales se retrouvent dans la version doublée : (1) l’introduction d’une interlangue, c’est-à-dire que les personnages anglophones parlent français avec un fort accent et des interférences ; (2) la reformulation des dialogues en français, de sorte que, bien qu’ils ne soient pas fidèles au contenu, ils créent une situation qui correspond plus ou moins aux contraintes visuelles ‍; (3) le maintien des interventions en français sans modifications, ce qui peut conduire à des situations quelque peu invraisemblables ; et (4) l’introduction de l’anglais afin de créer un texte méta multilingue.
Analyse contrastive de connecteurs de cause en français et en mandarin standard1. Point de vue syntactico-sémantique
Authors: Wang Zhichao
Published: January 2025

Du point de vue syntactico-sémantique, cet article se focalise sur l’analyse contrastive des connecteurs de cause en français et en mandarin standard tels que parce que, puisque, car, 因为yīnwéi , 由于yóuyú et 既然jìrán. L’article analyse les contraintes syntaxiques de ces connecteurs dans les deux langues ; il présente les propriétés sémantiques de ces connecteurs dans l’approche modale en expliquant les liens entre ces contraintes syntaxiques et les différentes modalités des connecteurs afin de proposer un classement modal avec plus de pertinence que les analyses sémantiques dans les recherches antérieures.
Triompher du silence : la conquête féministe de la littérature ernauxienne
Authors: Sueza Espejo María José
Published: January 2025

Le jury qui a décerné le Nobel à Annie Ernaux en 2022 a souligné « le courage et l'acuité clinique avec lesquels elle dévoile les racines, les éloignements et les freins collectifs de la mémoire personnelle”.  Nous observons ces éloignements et freins collectifs dans une question qui a été beaucoup plus qu’un frein pour les femmes: le silence qui leur était imposé comme complément supplémentaire aux autres restrictions qu’elle devait accepter de bon gré, servant à la circonscrire au domaine privé et domestique, gouverné par l’homme, ainsi qu’à celui de l’interdiction de parler ou s’exprimer sur quoi que ce soit. Nous analyserons des ouvrages de la littérature ernauxienne dans le but de découvrir la révolte de l’écrivaine contre cette imposition, qui a brisé les tabous sur des thématiques féminines, s’est fait entendre par le biais de son écriture, contribuant à la conquête de sa liberté, de la liberté des femmes.
Représentations de l’espace naturel dans l’oeuvre poétique de Jordi Pere Cerdà
Authors: Marqués Meseguer Josep
Published: January 2025

Cet article analyse les différentes manières utilisées par Jordi Pere Cerdà (Saillagouse, Cerdagne, 1920 - Perpignan, 2011) pour représenter la nature dans plusieurs poèmes de son oeuvre lyrique. L’évocation de la nature étant un recours thématique habituel dans son oeuvre littéraire, nous nous interrogerons sur la manière dont les éléments naturels sont représentés poétiquement, ainsi que sur les différents procédés utilisés dans chaque poème analysé. Pour organiser thématiquement les éléments abordés, nous traiterons de la description de l’environnement de la Cerdagne, de la représentation de la frontière franco-espagnole à travers la nature, du lien entre les habitants de la Cerdagne et le milieu naturel, et enfin de l’exercice d’introspection de l’auteur vis-à-vis de son propre territoire cerdan, de sa culture et de l’acte créateur en tant que poète
Şizofreninin Tanısında Yapay Zekanın Kullanımına Dair Sistematik Derleme
Authors: Kaya Buğra
Published: January 2025

This systematic review investigates the use of artificial intelligence (AI) in the diagnosis of schizophrenia, analyzing studies published between 2010 and 2024 in Turkish and English literature. Conducted using a systematic review methodology, the study evaluates the effectiveness and limitations of AI-based methods in schizophrenia diagnosis. Data was collected from the Google Scholar database in accordance with PRISMA guidelines. Neuroimaging techniques (fMRI, MRI), EEG, and natural language processing were highlighted as prominent methods.The findings reveal that AI has achieved accuracy rates of up to 99.25% in diagnosing schizophrenia and contributed to personalized treatment processes. However, challenges such as limited sample sizes, ethical concerns, and difficulties in integrating AI methods into clinical applications were identified. The study emphasizes the significant potential of AI in early diagnosis and risk prediction but highlights the need for further research involving larger and more diverse populations.
Keywords: Schizophrenia, Artificial Intelligence, Systematic Review
EVIDENCE BASED CASE REPORT (EBCR): PENGARUH TERAPI KOMPRES DINGIN TERHADAP NYERI LUKA PERINEUM DI PUSKESMAS RANCAEKEK DTP
Authors: Sandy Aulia Putri , Neneng Widaningsih  , Chris Sriyanti
Published: January 2025

Pravalensi ibu bersalin yang mengalami luka perineum di Indonesia pada golongan umur 25-30  tahun yaitu  24%  sedangkan  pada  ibu  bersalin  usia  32-39  tahun  sebesar  62%. Nyeri yang ibu rasakan membuat ibu kesakitan, menghambat mobilisasi, hingga menghambat proses pemulihan masa nifas. Pemberian obat farmakologi pun dikhawatirkan akan berdampak pada kandungan ASI dan membahayakan bayi, sehingga diperlukan penerapan metode non farmakologi. Kompres dingin merupakan pemberian stimulus kutaneus dengan pemanfaatan suhu, bekerja dengan cara menurunkan kecepatan hantaran syaraf, sehingga impuls nyeri yang sampai ke otak lebih sedikit dan menurunkan sensasi nyeri yang dirasakan. Tujuan dari laporan ini untuk mengetahui apakah terdapat pengaruh pemberian kompres dingin terhadap pengurangan nyeri luka jahitan di jalan lahir. Metode yang dilakukan ialah penelusuran artikel dengan menggunakan databased Garuda, Pubmed, dan Elsevier. Intervensi dilakukan dengan menerapkan kompres dingin pada ibu selama 10 menit dan diulangi dalam 30 menit sebanyak dua sesi. Hasil yang didapatkan dari penilaian nyeri yang dirasakan ibu menggunakan Wong-Baker Pain Rating Scale sebelum dan sesudah intervensi menunjukkan perbedaan yang signifikan dengan penurunan sebanyak lima skala. Dengan demikian, pemberian kompres dingin secara jangka pendek efektif terhadap penurunan rasa nyeri luka jahitan perineum.
HUBUNGAN ANTARA UMUR DAN PARITAS IBU DENGAN KEJADIAN PERSALINAN PRETERM DI RSUD KOTA PRABUMULIH TAHUN 2023
Authors: Novitasari  , Sutandar Vivi Hendra , Juninta Tania
Published: January 2025

Penurunan angka kematian bayi di Indonesia turun jauh hingga 90% dalam 50 tahun atau sejak 1971 hingga 2020. Dalam 1 dekade atau dari tahun 2010 sampai 2020, penurunan kematian bayi di Indonesia mencapai 35% (BPS). Penelitian ini bertujuan untuk mengetahui apa yang menyebabkan terjadinya kelahiran preterm di RSUD Prabumulih di tahun 2023.  Penelitian ini menggunakan Deskriptif Analitik dengan menggunakan pendekatan Cross Sectional. Populasi ini adalah keseluruhan ibu bersalin yang berjumlah 2.242 orang. Sampel berjumlah 339 responden. Pada Analisa univariat didapatkan ibu yang mengalami kejadian persalinan preterm sebanyak 114 responden (28,6%) dan yang tidak mengalami kejadian persalinan preterm sebanyak 285 responden (71,4%). Paritas ibu  yang berisiko akan mengalami persalinan preterm berjumlah 192 responden (56,6%) dan paritas ibu yang tidak beresiko akan mengalami kejadian persalinan preterm berjumlah 147 responden (43,4%). Analisa bivariat menunjukkan umur ibu mempunyai hubungan yang bermakna dengan kejadian persalinan preterm (p value 0,000), sedangkan paritas ibu tidak mempunyai hubungan yang bermakna dengan kejadian persalinan preterm (p value 0,407). Kesimpulan adalah bahwa ada hubungan antara umur dengan kejadian persalinan preterm dan tidak ada hubungan antara paritas dengan kejadian persalinan preterm di RSUD Kota Prabumulih Tahun 2023.
EFEKTIVITAS WOOLWICH MASSAGE TERHADAP PRODUKSI ASI PADA IBU POST PARTUM
Authors: Valencia Frenalia , Renda Natalina
Published: January 2025

Salah satu kegagalan dalam pemberian ASI Ekslusif adalah tidak segera keluarnya ASI setelah ibu melahirkan. Hal ini dikarenakan kurangnya rangsangan hormone prolactin dan oksitosin yang sangat beperan dalam kelancaran ASI. Upaya yang dapat dilakukan untuk merangsang hormone prolactin dan oksitosin pada ibu nifas dengan memberikan sensasi rileks pada ibu yaitu dengan melakukan massage woolwich. Penelitian ini bertujuan untuk mengetahui efektivitas woolwich massage terhadap produksi ASI pada ibu post partum Di Praktik Bidan Mandiri Kota Palembang. Penelitian ini merupakan penelitian Quasi eksperimental posttest only with control group design. Pengukuran produksi ASI pada kelompok perlakuan dan kelompok kontrol menggunakan kuesioner. Hasil penelitian menunjukkan terdapat pengaruh efektivitas woolwich massage terhadap produksi ASI (p<0,05). Bidan sebagai garda terdepan dalam pemberi pendidikan kesehatan kepada ibu yang diharapkan dapat membantu para ibu hamil dan menyusui untuk tetap memberikan ASI pada bayi di awal kehidupannya.
Analyzing Priority for Protected Area Expansion Based on Predicting Mammals’ Habitat Distribution Using SSP Scenarios.
Authors:   Graduate School of Environmental Landscape Architecture, Cheongju University, Korea, Song Yun Ju , Shin Wonhyeop ,   Interdisciplinary Program in Landscape Architecture, Seoul National University, Seoul 08826, Korea,   Transdisciplinary Program in Smart City Global Convergence, Seoul National University, Seoul 08826, Korea, Gyu Jeong Seung , Suh Jae-Hwa , Kim Yu Jin , Hwang In Jae ,   Climate Change and Environmental Biology Research Division, National Institute of Biological Resources, Korea, Kim Ho Gul ,   Department of Landscape Architecture and Urban Planning, Cheongju University, Korea.
Published: January 2025

Protected areas play a crucial role in mitigating the impact
of climate change on biodiversity. However, traditional
methods of expanding protected areas have focused solely
on increasing area size to meet the Convention on Biological
Diversity (CBD) objectives, without considering the effects of
climate change. This study aims to address the limitations of
previous research by analyzing the impact of climate change
on biodiversity. It prioritizes protected areas by examining
changes in key habitats for 10 South Korean mammal
species across three periods: A (2011-2040), B (2041-2070),
and C (2071-2100). Two scenarios were used: SSP1-2.6 (active
mitigation) and SSP3-7.0 (passive mitigation). In the SSP1-
2.6 scenario, key habitat areas decreased in period B but
gradually recovered in period C, while in SSP3-7.0, habitat
areas slightly increased in period B but decreased again in
period C. The findings suggest that climate change mitigation
policies significantly affect habitat area changes. Based on
this analysis, the study recommends prioritizing southern
Gangwon-do and northern Gyeongsangbuk-do as first-priority
protected areas, with Demilitarized Zone (DMZ)-adjacent
regions, eastern Gyeonggi-do, and western Gangwon-do as
second priorities for future conservation efforts. It is expected
that the proposed key habitat areas will be a useful reference
for future mid- to long-term expansion of protected areas.
Organic Farming: A Pathway to Sustainable Development
Authors: Akhuli Swarup
Published: January 2025

Organic farming is a comprehensive agricultural approach that focuses on sustainable development by fostering ecological balance, biodiversity, and soil health. It avoids the use of synthetic chemicals, pesticides, and genetically modified organisms (GMOs), instead relying on natural processes and organic inputs for crop cultivation and livestock management. This method plays a crucial role in addressing environmental challenges, enhancing food security, and supporting healthy ecosystems. At its core, organic farming embodies environmental sustainability, promoting ecological harmony, reducing environmental degradation, and preserving biodiversity through the use of natural methods and materials. This paper delves into the role of organic farming in advancing sustainable development by analyzing its environmental, economic, and social aspects.

Keywords: Organic farming, sustainable agriculture, ecological practices, soil health, sustainable development.
'It was the most important and memorable part of my studies…': Greek graduate teachers evaluate their practicum
Authors: Lozgka Evangelia
Published: January 2025

Teaching practicum is crucial in initial teacher education programs, determining their effectiveness and attracting researchers’ and practicing teachers’ attention. This study explores the experiences of ten graduate teachers (eight women and two men) from a university department in Greece regarding their internship during their undergraduate studies. Unlike similar studies, this study utilized the free text written by the participants as a research tool to highlight the topics that really interest the practicing teachers. The data was analyzed using qualitative content analysis. From the analysis, eight main categories emerged describing trainees’ internship experiences: a) characterizations for the teaching practicum, b) emotions from the practicum, c) benefits and usefulness of the process, d) positive and e) negative aspects of the practicum, f) difficulties encountered, and g) recommendations for improving the practicum. These findings offer valuable feedback for enhancing the internship experience within the participants’ department and stress the need for further research on the multi-factorial process of teaching practicum.
The Synergistic impact of three pillars of human intelligence EQ, CQ, and Communication Quotient on Organizational Success
Authors: Makhzoum Violla , Chami Heba
Published: January 2025

Many studies have been conducted to discover the different quotients of human intelligence because it attracts the interest of both the popular literature and within academia. The primary aim of this paper is to explore the interplay between different quotients of human intelligence including emotional intelligence quotient , communication quotient and creativity quotient to foster a culture of innovation and increasing productivity and employee satisfaction . Data for the study were collected for the field study from124 administrative employees working in private schools in Beirut, Lebanon to explain the importance of these three quotients.
The descriptive analytical method was used depending on a closed survey to collect data. The findings show a relationship between the three quotients. emotional intelligence effects interpersonal relationship which positively effects strategic and therefore improve their employment competitiveness and administrative skills. Additionally, EQ, CQ, and communication skills
Hepatic arterial infusion pump chemotherapy for colorectal liver metastases: Revisiting traditional techniques to explore new frontiers
Authors: Messaoudi Nouredin , Vanlander Aude , Benhadda Myriam , Makarian Roza , Kortbeek Koen , De Haar-Holleman Amy , Gumbs Andrew A
Published: January 2025

Hepatic arterial infusion (HAI) chemotherapy, first introduced in the 1980s, has gained recognition as an effective locoregional treatment for colorectal liver metastasis (CRLM). Initially used for unresectable liver metastases, HAI’s application has expanded to the adjuvant setting following hepatic resection, with early studies indicating improved hepatic disease-free survival. Recent research demonstrates that combining HAI with modern systemic therapies enhances conversion to resectability and prolongs both recurrence-free and overall survival, even in heavily pretreated patients with diverse RAS mutational statuses. Personalization through approaches like microsatellite instability status and dose modifications further optimize outcomes. However, the complexity of HAI requires expertise across multidisciplinary teams, limiting its widespread adoption to specialized centers. Ongoing clinical trials continue to investigate HAI’s role in CRLM management, highlighting its potential to become a cornerstone of liver-directed therapy. We explore how HAI chemotherapy, in combination with personalized medicine, can advance treatment strategies for metastatic colorectal cancer.
Therapeutic potential of kakkatin derivatives against hepatocellular carcinoma
Authors: Chahal Sahiba , Patial Vikram
Published: January 2025

In this article, we commented on the work done by Jiang et al , where they synthesized a kakkatin derivative, 6-(hept-6-yn-1-yloxy)-3-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one (HK), and investigated its antitumor activities and mechanism in gastric cancer MGC803 and hepatocellular carcinoma (HCC) SMMC-7721 cells. HK was evaluated for its antitumor activity as compared to kakkatin and cisplatin. This article focused on various risk factors of HCC, the mechanism of HCC progression and molecular targets of the kakkatin derivative, and limitations of available treatment options. HCC is a predominant form of primary liver cancer characterized by the accumulation of multiple gene modifications, overexpression of protooncogenes, altered immune microenvironment, and infiltration by immune cells. Puerariae flos (PF) has been used in traditional medicine in China, Korea, and Japan for lung clearing, spleen awakening, and relieving alcohol hangovers. PF exerts antitumor activity by inhibiting cancer cell proliferation, invasion, and migration. PF induces apoptosis in alcoholic HCC via the estrogen-receptor 1-extracellular signal-regulated kinases 1/2 signaling pathway. Kakkatin isolated from PF is known as a hepatoprotective bioflavonoid. The kakkatin derivative, HK, exhibited anticancer activity against HCC cell lines by inhibiting cell proliferation and upregulating nuclear factor kappa B subunit 1 and phosphodiesterase 3B. However, further preclinical and clinical studies are required to establish its therapeutic potential against HCC.
Checkpoint kinase 1 in colorectal cancer: Upregulation of expression and promotion of cell proliferation
Authors: Pang Yu-Yan , Chen Zu-Yuan , Zeng Da-Tong , Li Dong-Ming , Li Qi , Huang Wan-Ying , Li Bin , Luo Jia-Yuan , Chi Bang-Teng , Huang Qiu , Feng Zhen-Bo , He Rong-Quan
Published: January 2025

BACKGROUND

Colorectal cancer (CRC) is a prevalent malignant tumor characterized by a high mortality rate, with significant challenges persisting in the identification and management of its metastatic stage. The role of checkpoint kinase 1 (CHEK1), a cell cycle checkpoint kinase, in CRC has not been fully clarified. We hypothesize that the upregulation of CHEK1 may enhance the proliferation of CRC cells, indicating its potential as a novel therapeutic target for CRC therapy.

AIM

To investigate the expression and function of CHEK1 in CRC, this study utilizes single-cell RNA sequencing and tissue microarray data.

METHODS

Single-cell RNA sequencing technology was employed to analyze CRC cells from the GSE144735 dataset, and immunohistochemistry was conducted to confirm the expression of CHEK1 in CRC and adjacent tissues. We also integrated mRNA expression data from multiple public databases to assess global CHEK1 expression in CRC. Molecular docking experiments were performed to explore the interaction between CHEK1 and the potential drug nitidine chloride (NC), as well as to investigate the influence of CHEK1 on CRC cell proliferation.

RESULTS

We found comparatively elevated CHEK1 expression in the malignant epithelial cells of CRC, with marked upregulation of its mRNA levels in CRC tissues. Immunohistochemical analysis further confirmed the high expression of CHEK1 in CRC tissues, and the receiver operating characteristic curve demonstrated high accuracy (area under the curve = 0.964) for CHEK1 as a biomarker. Analysis of global datasets indicated a statistically significant overexpression of CHEK1 in CRC (standard mean difference = 1.81, P < 0.01), with summary receiver operating characteristic analysis yielding sensitivity and specificity values of 0.83 and 0.88, respectively. Molecular docking studies indicated that NC specifically targeted CHEK1, while clustered regularly interspaced short palindromic repeats knockout experiments demonstrated that CHEK1 promoted CRC cell proliferation.

CONCLUSION

Upregulation of CHEK1 promotes CRC cell proliferation. However, the dataset's diversity is limited, requiring further investigation into its specific mechanisms.
Targeted maintenance therapy for a young woman with cervical rhabdomyosarcoma: A case report and review of literature
Authors: Ma Huan-Ran , Zhang Dan , Li Li , Qi Lin , Wang Liang , Li Yi-Tong , Wang Ya-Ru
Published: January 2025

BACKGROUND

Rhabdomyosarcoma of the uterine cervix is a rare form of soft-tissue sarcoma predominantly affecting young women, with no established standard treatment protocol.

CASE SUMMARY

This report presents a case of a 17-year-old female patient presenting with intermittent, non-cyclical vaginal bleeding and associated lower abdominal pain. Pelvic magnetic resonance imaging and additional examinations led to the diagnosis of cervical rhabdomyosarcoma. The primary treatment options for uterine cervical rhabdomyosarcoma include surgery, with or without adjuvant chemotherapy and radiotherapy. This patient underwent surgery followed by a postoperative chemotherapy regimen of gemcitabine combined with docetaxel and bevacizumab. After 19 months of follow-up, the patient showed no signs of recurrence and maintained good overall health. Given the rarity of cervix rhabdomyosarcoma, this case is presented to provide insights into the diagnosis and treatment of this condition.

CONCLUSION

This suggests that bevacizumab may demonstrate potential efficacy in the treatment of cervical rhabdomyosarcoma. In the future, targeted therapy is expected to play an increasingly significant role in the management of rhabdomyosarcoma.
Advances in radiotherapy in the treatment of esophageal cancer
Authors: Rao Vrushab , Singh Soumya , Zade Bhooshan
Published: January 2025

Recent advancements in radiotherapy for esophageal cancer have significantly improved treatment outcomes and patient quality of life. Traditional radiotherapy techniques have been enhanced by the integration of advanced imaging and precision targeting technologies, such as intensity-modulated radiotherapy and proton therapy, which allow for more accurate tumor targeting while minimizing damage to surrounding healthy tissues. Additionally, combining radiotherapy with immunotherapy has shown promising results, leveraging the body’s immune response to enhance the effectiveness of cancer treatment. Studies have also highlighted the benefits of neoadjuvant chemoradiation followed by surgical resection, which has been associated with improved overall survival rates compared to radiotherapy alone. These innovations are paving the way for more effective and personalized treatment strategies, offering new hope for patients with esophageal cancer.
Therapeutic insights into epidermal growth factor receptor/reactive oxygen species proto-oncogene 1-receptor co-mutated non-small cell lung cancer: Crizotinib as a promising option
Authors: Zhou Yan , Xu Bo-Tao , Zhou Hai-Ying , Shang Zhong-Tu
Published: January 2025

This letter provides a review of the report by Peng et al on a unique case of non-small cell lung cancer (NSCLC), specifically lung adenocarcinoma, featuring reactive oxygen species proto-oncogene 1-receptor (ROS1) co-mutation. The case involves a 64-year-old patient who exhibited both epidermal growth factor receptor (EGFR) L858R mutation and ROS1 rearrangement, achieving significant disease stabilization following treatment with crizotinib. This rare EGFR/ROS1 co-mutation poses distinct challenges for clinical management and highlights the necessity of personalized treatment strategies. While third-generation EGFR tyrosine kinase inhibitors (TKIs), such as osimertinib, are commonly regarded as first-line therapies, recent studies indicate that crizotinib may offer superior disease control in certain EGFR-mutant patients, particularly those who exhibit poor responses to EGFR TKIs. The case also examines the influence of tumor cell genetic heterogeneity on treatment response, underscoring the importance of evaluating tumor characteristics. In patients with EGFR/ROS1 co-mutation, gefitinib is generally effective as a first-line treatment; however, its efficacy can be limited, whereas crizotinib has demonstrated improved disease control. Future research should focus on identifying optimal treatment strategies for patients with EGFR/ROS1 co-mutation to enhance patient outcomes. In conclusion, this case report not only illustrates the effectiveness of crizotinib in managing patients with EGFR/ROS1 co-mutation but also underscores the importance of personalized treatment approaches, offering valuable insights for improving clinical outcomes in NSCLC patients with complex genetic profiles.
Enrique Gajardo Velásquez (1923-1999): disruptor del Teatro Moderno en Chillán
Authors: Reyes Coca Marco
Published: January 2025

El maestro Enrique Gajardo, impulsado por su amor a las Artes Escénicas y a la radiodifusión educativa, provocó un “reventón
cultural” en el Chillán de los años que van desde 1940 hasta 1999. Al crear el Instituto de Extensión Cultural de Chillán (INECUCH),
se empeñó en culturizar a una comunidad estática y retrógrada, mediante el poder comunicacional de la radiodifusión. En tanto
desde 1951, mediante el Teatro de la Universidad de Chile-Chillán, creó una verdadera “usina teatral” desde la Sala Shaefer, representando obras clásicas y contemporáneas, sembrando “semillas que siguen germinando”.