bluuebunny/crossref_metadata_2025 huggingface dataset:
RESULTS OF SURGICAL TREATMENT OF ACUTE LOWER LIMB ISCHEMIA IN PATIENTS WITH SARS-COV-2 INFECTION
Authors:   Belarusian State Medical University, V. Khryshchanovich ,   4th City Clinical Hospital N.E. Savchenko, I. Klimchuk ,   Belarusian State Medical University,   4th City Clinical Hospital N.E. Savchenko, N. Rogovoy ,   Belarusian State Medical University,   4th City Clinical Hospital N.E. Savchenko, E. Nelipovich ,   Belarusian State Medical University,   4th City Clinical Hospital N.E. Savchenko, A. Pavlov ,   Belarusian State Medical University,   4th City Clinical Hospital N.E. Savchenko
Published: September 2022

Coronavirus disease 2019 (COVID-19) refers to viral respiratory infections and is the predisposing factor for the development of venous and arterial thrombotic events due to a pronounced inflammatory response, platelet activation, endothelial dysfunction and stasis. Recent studies have confirmed an extremely high incidence of thromboembolic events, especially in the group of patients with severe coronavirus pneumonia. There have been an increasing number of reports of peripheral arterial thrombosis as well. Most cases of arterial thrombosis are noted in critically ill patients in intensive care units. At the same time, acute limb ischemia often occurred in the absence of serious comorbid conditions and was accompanied by high rates of amputations and deaths. Herein we report the results of management of 14 patients with severe SARS-CoV-2 infection and acute lower limb ischemia. Our own series of clinical observations shows that open thrombectomy and standard parenteral anticoagulation are ineffective in more than one third of cases. The pathogenesis mechanisms of COVID-19-associated arterial thrombosis should be further investigated in order to develop an optimal therapeutic strategy.
REVIEW OF THE AAGT INTENSIVE CARE COMMITTEE CLINICAL CONSENSUS ON THE MANAGEMENT OF PATIENTS WITH RHABDOMYOLYSIS
Authors:   Belarusian State Medical University, A. Titova , M. Terenin ,   6th City Clinical Hospital, I. Dovgalevich ,   Belarusian State Medical University, S. Motuz ,   6th City Clinical Hospital, Minsk Belarus, A. Mishchenko ,   Chausskaya Central District Hospital
Published: September 2022

Rhabdomyolysis is a condition characterized by the primary (mechanical) or the secondary (metabolic) damage to skeletal muscles, resulting in cell death and massive release of potentially toxic substances into the general circulation. Alertness to this complex pathological condition is very low among primary care physicians. Most often, traumatologists-orthopedists and resuscitators deal with the clinical picture of rhabdomyolysis. However, an in-depth analysis of literature data on the etiopathogenesis of this process implies a wide range of specialties, who need knowledge of the clinical picture of the development of rhabdomyolysis as well as of therapeutic specifics and prevention to manage this specific contingent patient. At the end of 2021, the clinical consensus of the intensive care committee of the American Association for the Surgery of Trauma (AAST) took place, which resulted in the formulation of recommendations for the management of patients with rhabdomyolysis. The document reviews and compiles knowledge of the causes of muscle fiber breakdown, iagnosis, treatment, and outcomes of acute rhabdomyolysis in critically ill patients.
A new digital lithological map of Italy at the 1:100 000 scale for geomechanical modelling
Authors: Bucci Francesco , Santangelo Michele , Fongo Lorenzo , Alvioli Massimiliano , Cardinali Mauro , Melelli Laura , Marchesini Ivan
Published: September 2022

Abstract. Lithological maps contain information about the different
lithotypes cropping out in an area. At variance with geological maps,
portraying geological formations, lithological maps may differ as a function of their purpose. Here, we describe the preparation of a lithological map of
Italy at the 1:100 000 scale, obtained from classification of a
comprehensive digital database and aimed at describing geomechanical properties. We first obtained the full database, containing about 300 000
georeferenced polygons, from the Italian Geological Survey. We grouped polygons according to a lithological classification by expert analysis of the 5456 original unique descriptions of polygons, following compositional and geomechanical criteria. The procedure resulted in a lithological map with a legend including 19 classes, and it is linked to a database allowing
ready interpretation of the classes in geomechanical properties and is amenable to further improvement. The map is mainly intended for statistical
and physically based modelling of slope stability assessment and geomorphological and geohydrological modelling. Other possible applications include geoenvironmental studies, evaluation of river chemical
composition, and estimation of raw material resources. The dataset is publicly available at https://doi.org/10.1594/PANGAEA.935673
(Bucci et al., 2021).
Understanding the drift of Shackleton’s Endurance during its last days before it sank in November 1915 using meteorological reanalysis data
Authors: de Vos Marc , Rabenstein Lasse , Kountouris Panagiotis , Shears John , Suhrhoff Mira , Katlein Christian
Published: September 2022

Abstract. On 5 December 1914, Sir Ernest Shackleton and his crew set sail from South Georgia aboard the wooden barquentine vessel Endurance, thus beginning the Imperial Trans-Antarctic Expedition to cross the Antarctic continent. However, Shackleton and his crew never reached land because the vessel became beset in the sea ice of the Weddell Sea in January 1915. Endurance then drifted in the pack for eleven months, was crushed by the ice and sank on 21 November 1915. Over many years, various predictions were made about the exact location of the wreck. These were based largely on navigational fixes taken by Captain Frank Worsley, the navigator of the Endurance, three days prior to, and one day after the sinking of Endurance. On 5 March 2022, the Endurance 22 expedition successfully located the wreck some 7.8 km southeast of Worsley’s estimated sinking position. In this paper, we describe the use of meteorological reanalysis data to reconstruct the likely ice drift trajectory of Endurance for the period between Worsley’s final two fixes, at some point along which she sank. This approach yields a mean 24-hour position error of 4 to 10 km, and a predicted location some 2 to 5.3 km from the position at which the wreck finally was found. In spite of numerous sources of uncertainty, these results show the potential for such methods in marine archaeology.
PENERAPAN METODE PENETRASION TESTING PADA KEAMANAN JARINGAN NIRKABEL
Authors: Santoso Nugroho Adhi , Ainurohman Muhamad , Kurniawan Rifki Dwi
Published: September 2022

Penerapan Keamanam jaringan nirkabel merupakan sebuah sistem yang digunakan untuk meindentifikasi dan melakukan pencegahan pencurian data dan informasi pada jaringan komputer. Kekurangan jaringan nirkabel menjadi semua pengguna dapat mendeteksi sinyal radio sesuai jenis frekuensi beberapa tools yang tersedia secara bebas di internet untuk mendapatkan hak akses kontrol secara tidak sah. Pada Metode yang digunakan pada penelitian ini adalah penetration testing untuk menguji keamanan jaringan nirkabel  di SMK Bhakti Praja Adiwerna Kabupaten Tegal dengan batasan pada frekuensi 2,4 GHZ dan 5 GHZ, Dengan Berbagai macam ketegori perangkat jaringan router dan Acces point. Tujuannya untuk Menguji keamanan pada jaringan nirkabel menggunakan tools yang tersedia pada sistem operasi kali linux versi 2021.1. Hasil dari penelitian ini dapat disimpulkan bahwa metode penestrasion testing mempunyai suatu kelebihan dapat menguji jaringan Nirkabel dan dapat menindetenfikasi WPA Key dengan database Wordlist sehingga dapat menjadi bahan untuk penerapan Keamanan pada jaringan nirkabel.
Bayesian model selection and inference for field studies of soil carbon cycling
Authors:   , Davoudabadi Mohammad Javad
Published: September 2022

Farmers and land managers can yield financial gains through the sale of carbon credits. They typically rely on computationally complex models fit using sparse datasets to make predictions concerning soil carbon stocks and associated carbon accounts which can lead to over-fitting. We develop new soil carbon models to address the over-fitting issue and evaluate the effect of microbial biomass on modelling soil carbon sequestration. Also, we introduce and evaluate advanced Bayesian methods to improve the speed of computation and accuracy of predictions of soil carbon stocks.
Development of an integrated process for biogas production from sugarcane trash
Authors:   , Ketsub Napong
Published: September 2022

This project is the systematic study on how to utilise sugarcane trash for biogas production using an integrated process. A suitable pretreatment for sugarcane trash preparation was successfully developed and a key microbial response was identified during anaerobic digestion of the pretreated sugarcane trash. Moreover, the pretreatment and anaerobic digestion process was designed to integrate with hydrothermal carbonisation to utilise anaerobic digestion residue for further improvement of process performance. Biogas production was improved via the proposed integrated process, which has the ability to be developed further as a commercial fuel source.
Doing dementia friendly communities locally: Tensions in committee practices and micro-processes
Authors:   , Grogan Caroline
Published: September 2022

This thesis explored the micro-processes of Dementia Friendly Community principles through committees. Using micro-ethnography and a case study approach, two Australian- Queensland DFC committees were studied to better understand local-level implementation. This involved semi-structured interviews, participant observation, and field notes. Findings from this study illustrated that while both committees had well-meaning intentions, stark differences in structure, processes, and approaches were evident. To enable full participation of people living with dementia in local committees, understanding and awareness of inclusive micro-processes are key. Integrating Community Development with a DFC approach also helps address the gaps in processes to build authentic sustaining DFCs.
The Significance of Cytoplasmic Fluorescence Antinuclear Antibody in Autoimmune Liver Diseases
Authors: Kurti Margarita
Published: September 2022

Autoimmune liver disease (AILD) is a rare immune-mediated chronic liver disease with heterogeneous clinical characteristics. There are many cases of hepatitis and cholestasis of unknown etiology that Antinuclear antibody (ANA) are accompanied by specific antibodies for AILD.
We aimed to determine the significance of cytoplasmic antinuclear antibody (ANA) patterns in patients with AILD.
Material and Methods: We retrospectively reviewed all patients were sent to our laboratory from 2016 till 2020 for ANA, Smooth muscle antibody (SMA) and Antimitochondrial antibody (AMA). We examined the diagnoses of the 218 excluded patients. ANA, AMA, SMA were performed by Immunofluorescence test (IFT). Fluorescence intensity was interpreted semi quantitatively
Results: Among 218 cases, 74 (29.4%) resulted as ANA positive and 120 (55%) resulted as cytoplasmic fluorescence positive. ANA resulted positive only in 29 cases. 45 cases resulted as ANA positive and cytoplasmic fluorescence positive. Of interest to study were 75 cases which resulted as ANA negative and cytoplasmic fluorescence positive. Only 69 cases resulted seronegative. All cases with positivity of cytoplasmic fluorescence, regardless of ANA resulted as 82 anti-SMA positive, 3 AMA positive and anti-SMA positive, 35 AMA positive. Furthermore, patients with AILD who exhibited a reticular ANA pattern demonstrated a higher positive rate for AMA 33 (86.8%) and those with the speckled ANA pattern displayed a higher positive rate for SMA 53 (64.6%).
Conclusion: Therefore, cytoplasmic ANA patterns could be used to guide AILD characterization in suspected AILD cases. Thus, it is important to check cytoplasmic ANA patterns for AILD evaluation, even when nuclear ANA patterns are negative.

Key words: Autoimmune liver disease, Antinuclear antibody, Smooth muscle antibody, Antimitochondrial antibody, Immunofluorescence test.
The Role of Healthy Vision in Educational Performance Among Secondary School Students in Federal Capital Territory (FCT) Abuja, Nigeria
Authors: Adekeye Oluwatoyosi Ayobami , Adekanye Feyishike Toyin
Published: September 2022

BACKGROUND: Approximately, eighty percent of the global burden of blindness occurs in developing countries. One in three of such cases affect children, are preventable, or treatable, mostly, using corrective lenses. Visual impairments can affect the development of a child, including their educational performance, social development and personal confidence. This study aims to determine the role of healthy vision in Educational Performance among secondary school students.
METHODS: This cross-sectional study consisted of qualitative data gathering conducted in Secondary Schools in the Federal Capital Territory (FCT) Abuja, Nigeria. It involved two focus group meetings and four semi-structured key informant interviews. This process was guided by a question guide, thematic content analyses was conducted, and subtle themes emerged.
RESULTS: The emergent themes were: "Knowledge on healthy vision" "Attitude towards maintaining healthy vision", and "Behaviors that promote healthy vision." Each theme consisted of a few sub-themes which further enriched the study results.
CONCLUSION: This study concludes that healthy vision promotes academic performance of secondary school students in Federal Capital Territory Abuja. Nigeria. Recommendations for future research, practice and policy were subsequently suggested.

Key words: Healthy Vision, Educational Performance, Secondary School Students, Federal Capital Territory, Knowledge on healthy vision
Validation and Reliability of the Gujarati Version of the Shoulder Activity Level Scale (SALS)
Authors: Kotecha Neeti I. , Sorani Dinesh , Kanabar Bhavesh
Published: September 2022

Background: Shoulder Activity Level Scale (SALS) is a reliable and valid tool that helps to measure Shoulder activity of an individual.
Materials and Method: SALS was translated into Gujarati from English using forward-backward-forward method. Face & content validity of Gujarati version of SALS is assessed by group consensus method. Group of experts in field of Medicine, Physiotherapy and language has analyzed each question for content, meaning, ease of administration. Concurrent validity has been assessed by comparing the English version of SALS with Gujarati version of SALS.
Statistical Analysis: Spearman’s correlation coefficient was used to assess the strength of association between the measures of both the versions. Cronbach’s alpha was used to assess reliability of Gujarati version of SALS
Results: There is a significant internal consistency (Cronbach’ alpha=0.895; p<0.05) and significant test-retest reliability found for SALS Gujarati version. Spearman’s correlation coefficient (ρ=0.94) suggested Significant correlation between original English and translated Gujarati scales.
Conclusion: Gujarati version of Shoulder Activity Level Scale has a good validity and reliability.

Key words: Gujarati SALS, translation of SALS, validity and reliability of Shoulder activity level scale.
Competency Based Integrative Medicine: Bridging the Odds
Authors: . Kanupriya , Patil Aditya Dilipkumar
Published: September 2022

CAM bears a holistic approach in synchronizing the relationship of mind and body in contrast with biomedical approach which are based on specific biomolecule docked with drug details. Acceptancy of quality of research in CAM remains scares due to heterogeneity of data and reproducibility of results in higher samples. In fact, researchers and academician must acknowledge the CAM and other cognitive science methods as combined mode of treatment for development of a competency-based approach in psychiatric illness which will strengthen the research. A commentary has been expressed for a correspondence published in Lancet Psychiatry series wherein Emotional Mental Imagery (EMI) has found to be useful from various clinical trials and reviews in curbing Anxiety and Depression. However, in upcoming times if EMI and AYUSH medication specifically Homoeopathy if adjunctly used might provide more effective guideline for treatment mode in condition of Anxiety and Depression.

Key words: Competency based Integrative Medicine, CAM, holistic approach
Awareness and Knowledge of Osteoporosis in Elderly Individual
Authors: Mavar Dr. Rachana , Thakrar Dr. Gira , Mukhi Dr. Sadhana
Published: September 2022

BACKGROUD: Elderly people may suffer from multiple health disorders due to the vulnerability for many physical and mental disturbances. Quality of life in elderly population can be affected by many environmental factors.
INTRODUCTION: Osteoporosis is a global public health problem which is commonly referred to as a systemic skeletal disease characterized by low bone tissue with a consequent increase in bone fragility and susceptibility to fracture. OPAAT scale assesses osteoporosis knowledge by asking participants to rate the likelihood of getting osteoporosis based on the type of preventive measures taken. The aim of our study was to assess the knowledge and awareness about osteoporosis in elderly individuals.
METHODOLOGY: We conducted a survey of 100 men and women aged ≥ 60 years. The validated Osteoporosis Prevention and Awareness Tool (OPAAT) was used to assess their knowledge about osteoporosis prevention and awareness and perceived barriers to osteoporosis screening. The OPAAT consists of 30 items, categorized into three domains. The higher scores indicate higher knowledge level. The domains of the scale are “osteoporosis in general”, “consequence of untreated osteoporosis” and “osteoporosis preventive measure”. A score of one was given for a correct response and zero for an incorrect or do not know response. The total score was converted into percentage ranging from 0–100.
RESULT: Present study determines that awareness and knowledge of osteoporosis in elderly individuals in general domain is 30.90%, knowledge of consequence of untreated osteoporosis is 39%, and knowledge of osteoporosis preventive measure is 38%.
CONCLUSION: Knowledge and awareness of osteoporosis in elderly individuals is low which suggests the need for increased awareness campaigns in the elderly population.

Key words: Elderly, Osteoporosis, OPAAT, Knowledge, Awareness.
Struma Ovarii Masquerading as a Mucinous Ovarian Cyst
Authors: Kirt Chadha , Kunjal Lila , Roshani Gala
Published: September 2022

Struma ovarii is an uncommon ovarian teratoma distinguished by the unusual presence of thyroid tissue. The vast majorities are benign, and ~5% are malignant. Clinical symptoms, laboratory investigations, imaging modalities are nonspecific. Even histopathologic features may be misleading in a few cases. It is defined as a teratoma composed exclusively of or containing more than 50% thyroid tissue. Common differentials include serous and mucinous cystadenoma. Awareness of existence of such entities may help in utilization of available histologic and imunohistochemical tools for correct diagnosis. Oophorectomy is the treatment of choice for benign struma.

Keywords: Struma ovarii, thyroid, teratoma, cystadenoma
The Effect of Framing, Halo Effect and Auditor's Experience on Audit Judgment
(Study on Auditors Public Accountant Office (KAP) in Medan City)
Authors: Fauzi Hasibuan Ahmad Kodri , Br Bukit Rina , Rini Endang Sulistya
Published: September 2022

This study aims to analyze and determine Framing, Halo Effect, and Auditor Experience on Audit Judgment. The population in this study is at the Medan KAP office, and the number of samples in this study is 50 people who work as auditors in the city of Medan. This study uses primary data from a questionnaire distributed to the research sample. Respondent data obtained and collected were then analyzed using SPSS tools. The analytical method used is descriptive statistics, classical assumption test, and multiple linear regression for hypothesis testing. Based on the data processing results using hypothesis testing, partially Framing and Halo Effect has a negative and insignificant effect on Audit Judgment. Auditor Experience has a positive and insignificant effect on Audit Judgment. Simultaneously, overall has a positive and significant influence. The predictive ability of these four variables on Audit Judgment is 32.6%, while other factors outside this research model influence the remaining 67.6%.

Keywords: Audit Judgment, Framing, Halo Effect, Auditor Experience
The Impact of Human Resource Flexibility on Organizational Success
Authors: Badi Abed Aldaiem Fadi Mohammad , Ali Abu-Helaleh Raba'a Salman
Published: September 2022

The Impact Of Green Supply Chain Management Practices On Competitive Advantage: Applied Study On Industrial Companies In Jordan.
The study aims to show the impact of green supply chain management practices and their impact on achieving competitive advantage in industrial organizations in Jordan. Descriptive and analytical approach was applied. The study sample of (200) employees in the supervision level(top management) in industrial organizations in the Hashemite Kingdom of Jordan. The researcher used a questionnaire to collect data that included the green supply chain management measure and the measure of competitive advantage, and verified indicators of its validity and reliability. The results of the study showed that the practices of green supply chain management in industrial organizations in Jordan came with a medium degree for all domains (green procurement, green manufacturing, green marketing) and the scale as a whole, and the competitive advantage in industrial organizations in Jordan came with a high degree for the scale as a whole and for the dimensions (creativity, quality, and Flexibility), while it was rated medium for the two dimensions (cost, and reputation). The results indicated that there is a statistically significant effect at the level of significance (α≤0.05) between green supply chain management prctices and all dimensions of competitive advantage (cost, quality, creativity, reputation, flexibility) and competitive advantage as a whole in industrial organizations.

Keywords: Green supply chain management practices, competitive advantage, industrial organizations, Jordan.
SUTURING TECHNIQUE FOR ESOPHAGOGASTRIC AND GASTROENTEROANASTOMOSIS DURING OPERATIONS ON THE ESOPHAGUS AND STOMACH
Authors: AMANOV Т.
Published: September 2022

Relevance: Esophageal cancer is in 4th place, and gastric cancer is in 3rd place in terms of cancer incidence in the West Kazakhstan region
(WKR). In 2019-2021, an average of 80-120 patients had identified annually, of which 40-50 patients underwent surgical treatment.
The study aimed to evaluate the effectiveness of the proposed improved method of suturing the anastomosis and enhancing the results of surgery by reducing postoperative complications in the form of anastomosis failure and reducing the time of the intra-operative period.
Methods: In 2019-2021, 150 operations on the esophagus and stomach were performed in the Regional Oncological Dispensary of the West
Kazakhstan Region (Uralsk, Kazakhstan) in the amount of Lewis operation – 76, Garlock operation – 29, extended gastrectomy – 45.
According to the method of M.I. Davydov, the standard technique of suturing includes four stages and involves the imposition of 16 stitches.
In the proposed version, an improved technique consisting of 3 steps is used without forming the second row of anterior lip anastomosis sutures.
The results were evaluated according to the following criteria: a) the number of cases of anastomosis failure compared to the standard procedure; b) the duration of the intraoperative period.
Results: Using an improved technique for applying esophagogastric and esophago-intestinal anastomosis has reduced the number of postoperative complications. So, from 2019-2021, postoperative complications decreased from 8.1% to 3.9%.
Conclusion: The effectiveness and practicality of the proposed technique of applying esophagogastric and esophago-intestinal anastomosis
during operations in patients with diseases of the esophagus and stomach have been proven.
THE IMPACT OF COVID-19 ON THE INCIDENCE OF RECTAL CANCER IN KAZAKHSTAN: RESULTS OF COMPONENT ANALYSIS
Authors: TELMANOVA Zh. , AXARIN A. , ORALBEK A. , OROZBAEV S. , KULAYEV K. , SHAPAMBAYEV N. , KUANDYKOV Y. , BILALOVA Z. , IGISSINOVA G. , RUSTEMOVA K. , KUDAIBERGENOVA I. , IGISSINOV N.
Published: September 2022

Relevance: Every year, 732,210 new cases of RC are registered globally, with an incidence of 7.6 per 100,000. The COVID-19 pandemic has affected the screening, case detection, and referral of patients with an asymptomatic cancer diagnosis.
The aim was to assess the trends in rectal cancer incidence in the entire population of Kazakhstan before and during the COVID
pandemics.
Methods: The data obtained from the Ministry of Healthcare of the Republic of Kazakhstan concerning RC (Form no. 7) was retrospectively studied by descriptive and analytical epidemiology methods. The component method was used to analyze RC incidence dynamics
based on the number of cases from 2010 to 2020.
Results: From 2010 to 2020, the risk of getting RC went down. An increase in incidence in 2010-2020 (+24.8%) was lower than in
the preCOVID period of 2010-2019 (+37.2%). We found a sharp decrease in RC incidence from 2019 to 2020. The overall decrease was
0.89‰⁰⁰ due to changes in the age structure of the population (∑ΔA=+0.13‰⁰⁰), the risk of getting RC (∑ΔR=−1.02‰⁰⁰), and the combined
impact of age structure and the risk of getting RC (∑ΔAR=−0.002‰⁰⁰). According to the component analysis, 1,662 patients with RC were
expected in 2020; instead, only 1,471 cases were registered. Such a decline in cases was mainly due to a reduced risk of getting RC.
Conclusions: The analysis of RC incidence trends in Kazakhstan shows a negative impact of COVID-19 on cancer care indicators and
effectiveness. All oncological examinations were strengthened with the resumption of work after COVID restrictions. However, the number
of screening visits remains lower than in previous years. Untimely diagnosis can increase the number of cases of late-stage CRC and an
overall loss of years of life due to the lack of proper treatment. However, these forecasts can be mitigated by proper follow-up
DETERMINATION OF THE SYNERGISTIC EFFECT OF CURCUMIN AND CARNOSIC ACID ON THE PROLIFERATION OF PROSTATE CANCER CELLS
Authors: OSSIKBAYEVA S.
Published: September 2022

Relevance: Cancer is one of the leading causes of death globally. The results of the conducted studies on the energy metabolism of
cancer cells can contribute to identifying molecular targets in the treatment of cancer. It is known that polyphenols widely distributed in
plants have an anti-cancer effect based on their well-known antioxidant, anti-inflammatory, antiproliferative, proapoptotic, and antiangiogenic potential.
Primary prostate cancer treatment methods include surgical resection and chemo- or radiation therapy. In the last decade, polyphenols
have attracted attention for use in complex prostate cancer chemotherapy. The search for natural compounds increasing the body’s resistance to tumor development and reducing the possibility of tumor recurrence after radiation or chemotherapy and studying their mechanisms of action are relevant directions for further in vivo research. In addition, there is a growing interest in studying practical treatment
approaches combining drugs with various mechanisms of action.
The study aimed to identify the synergistic effect of curcumin and carnosic acid on the proliferation of prostate cancer cells.
Methods: The proliferative activity of cells in culture on tablets, under the influence of polyphenols in various concentrations, was
evaluated by Alamar blue using a BioTek Synergy plate reader (BD Biosciences, San Jose, CA).
Results: При In determining the effect of naturally occurring polyphenols on prostate cancer cell proliferation, the effect of curcumin
was significantly greater than that of carnosic acid. In a higher concentration, their effect on the proliferation of prostate cancer cells was
higher and stopped cell growth by 30-60%, depending on the concentration and time of exposure.
Conclusion: A detailed evaluation of the data on inhibition of PC3, Du145 cell growth revealed a clear synergistic interaction between
curcumin and carnosic acid, which was especially strong at a concentration of curcumin 7 μM in combination with carnosic acid 5 μM
An Overview of Assessment Tools Used in Periodontics
Authors: Albalbisi Ayman , Almalki Nada , Bushnag Anaan , Alanazi Fahad , Alouf Aziz , Al Mousa Wala , Alshehri Ahmad , Almusalam Suliman , Alhazzani Hisham , Khalil Eman , Alrashidi Nada
Published: September 2022

Periodontal diseases refer to the diseases of gums or bone resulting in inflammation and loss of teeth. The disease affects adults more commonly, but children are also at risk of development of disease. Both modifiable and nonmodifiable risk factors play a vital role in progression of disease. Risk assessment is of utmost importance in periodontics as it contributes to early prevention and management of the disease thus decreasing rate of progression and associated complication. For the purpose of risk assessment various assessment tools are available that are routinely used by dental practitioners. The aim of this research is to review the available information regarding the assessment tools used in periodontics. American academy of periodontology self-assessment tool, oral health information suite, periodontal risk assessment hexagonal diagram, periodontal risk assessment model by Chandra, are some risk assessment tools used by dentists. Almost 20% of patient population who require treatment to prevent or slow the course of severe periodontal disease can be identified by utilization of a risk assessment questionnaire. The risk assessment findings can aid in clinical diagnosis and designing of an effective treatment strategy which can enhance the quality of dental care for patients. Well-established theoretical literature is present regarding these assessment tools but data about their clinical use and patient outcome is very limited. In future more clinical research is needed regarding the use of assessment tools in periodontics as they are quite important due to their role in early identification and intervention and also in predicting future outcome.a
Burden, Clinical Aspects and Management of Bronchial Asthma at Outpatient Clinics in Jeddah Saudi Arabia
Authors: El-Gamal Fathi , Bukhari Tala , Assiri Amjad , Abdulmohsen Sukaina , Yassin Zainab
Published: September 2022

Background: Asthma is a health disorder that is prevalent worldwide, and it imposes a great burden on primary health care (PHC) facilities. This work aims to study the magnitude and clinical aspects of bronchial asthma (BA) and to explore the pattern of its management at outpatient clinics (OPCs) in Jeddah, Saudi Arabia. Methods: A cross-sectional study enrolled 2,501 patients who visited the OPCs at two private hospitals in Jeddah during the study period. All patients were examined by a specialist. Data were collected using a checklist form to obtain personal characteristics, clinical assessment and management, as well as the outcome of the visits. Results: BA accounts for 4.27% of all visits, and for 19.49% of respiratory disorders visits to OPCs. Children under 6 years old were twice as likely to develop BA (OR: 1.89; 95% CI: 1.130, 3.147, p <0.015) compared to individuals older than 40 years. The common BA symptoms were cough (77.4%), dyspnea (42.5%), wheeze (29.2%), and sputum production (25.7%). CXR was the most frequent investigation performed on patients with BA (26.4%). No lung function or immunological tests were performed. Cortisol (21.7%), short-acting β2 agonist (21.7%), antibiotic (41%), paracetamol (17%), cough syrup and antihistamines (30% and 19.8%), and additionally, ketotifen (4.7%) and anti-leukotriene (7.5%) were prescribed to the patients. Counseling was neglected by physicians. The majority of cases were discharged. Conclusion: BA is a common cause for PHC visits. OPC management and use of antibiotics for BA should be revised with emphasis on adherence to the standard recommendations. PHC physicians should prioritize educating people about the prevention and control of BA.
Wykorzystanie współczynników akustycznych do analizy krajobrazu dźwiękowego
Authors: Ozga Agnieszka , Sapieja Kinga
Published: September 2022

Praca ma na celu zbadanie, czy współcześnie wykorzystywane wskaźniki akustyczne mogą mieć zastosowanie w monitorowaniu krajobrazu dźwiękowego ze szczególnym zwróceniem uwagi na ochronę enklaw ciszy występujących w środowisku urbanistycznym. Badanymi współczynnikami były: ACI – wskaźnik złożoności akustycznej, NDSI – wskaźnik znormalizowanej różnicy w krajobrazie dźwiękowym, BI – wskaźnik bioakustyczny, ADI – wskaźnik różnorodności akustycznej, AEI – wskaźnik równomierności akustycznej. W ramach pracy została utworzona baza 90 nagrań dźwiękowych, która została subiektywnie podzielona na trzy grupy: miejsca spokojne, miejsca rozrywki oraz miejsca, w których panuje hałas. Na tym etapie wykazano, że najczęściej rozróżnione zostały nagrania z miejsc spokojnych i miejsc rozrywki. W przypadku współczynnika BI nie udało się rozróżnić żadnej grupy.
Mikroprzestrzenie
Authors: Błażewicz Bożena
Published: September 2022

Artykuł jest formą krótkiego spaceru po działkach ROD. Opisuje fenomen funkcjonowania ogrodu działkowego, traktuje go jako specyficzną odmianę przestrzeni intymnej, jednej z bliższych człowiekowi, miejscem zaspokajania jego różnych potrzeb. Za jedną z tych potrzeb przyjmuje ludzką chęć tworzenia, budowania, anektowania przestrzeni według własnych reguł i zasad. Ogród działkowy jako miejsce znajdujące się poza oficjalną strefą miasta, z dala od normalnego codziennego życia, stwarza możliwość kreowania przez jego użytkownika nowej własnej rzeczywistości przestrzennej, nieograniczonej żadnymi barierami. Brama ROD staje się miejscem „przejścia” do innej rzeczywistości, pozwala zapomnieć o codziennych problemach i przenieść się w inny, oswojony wymiar.

 „Mary wsunęła ręce pod liście i poczęła je rozgarniać na boki. Gęsto wiszący bluszcz tworzył jakby luźną, powiewną zasłonę, chociaż część gałęzi pięła się na drzewo i po żelazie. Serce dziewczynki poczęło bić jak młotem, a ręce drżeć ze szczęścia i podniecenia. A rudzik śpiewał i ćwierkał dalej, tak przechylając główkę, jakby i on czuł się podniecony. Mary poczuła pod ręką kwadratowy, żelazny zamek z otworem na klucz(…) Słońce rzucało bogate snopy blasków na ten zamknięty w murach światek, a wysokie, błękitne niebios sklepienie wydawało się świetniejsze i cudniejsze jeszcze nad tym dziwnym zakątkiem Misselthwaite. Gil sunął z gałęzi i przeskakiwał za Mary z krzewów na krzewy, ćwierkał i miał strasznie zaaferowaną minę, jakby jej chciał coś pokazywać. Wszystko dokoła dziwne było i ciszy pełne i zdawało się, że Mary jest setki mil oddalona od wszystkiego, co żyje, a jednakże nie czuła się wcale osamotniona w tej chwili”
Pewne miejsce w internecie
Authors: Tarara Paulina
Published: September 2022

Analiza zjawiska-miejsca, jakim było The Place, z punktu widzenia performance’u kulturowego, technologicznego i organizacyjnego w rozumieniu McKenziego, a także zwrócenie uwagi na to, że zjawisko to było odbiciem i niezamierzoną symulacją naszych dążeń w świecie fizycznym (niewirtualnym). Przechodząc przez cykl życia: narodzin, wzrostu i śmierci, pozostaje cyfrowym zapisem symbolizującym władzę, wojnę, kreację i destrukcję.
Mokuhanga
Authors: Bożyk Marta
Published: September 2022

Drzeworyt japoński rozwijał się w Kraju Kwitnącej Wiśni od wielu lat i nieustannie zachwyca swoim pięknem oraz perfekcją w wykonaniu. Największym atutem dzieła sztuki jest jego technika wykonania. Wielu współczesnych artystów dziś czerpie inspiracje z dzieł japońskich twórców drzeworytów. W niniejszym artykule przedstawiono historię i technikę powstania drzeworytu japońskiego, omówiono twórczość wybranych współczesnych artystów, którzy tworząc swoją sztukę, zainspirowali się kunsztem drzeworytu japońskiego.
Artificial Intelligence in Food Industry: A Current Panorama
Authors: Bendre Sonam , Shinde Ketaki , Kale Niraj , Gilda Suhit
Published: September 2022

Artificial intelligence (AI) is that the theory and development of computer systems ready to perform tasks normally requiring human intelligence. With teeming competition and increasing demand within the food industry, has begun to embrace AI technologies during a bid to maximize profits and explore new ways to succeed in serve the consumers. AI has recently began to fix its application in various sector of the society with food industry as like pharmaceutical industry. This review highlights the impactful use of AI in diverse area of food sector including Sorting, Grading, Food Quality, Cleaning, Efficient Supply chain management, Microbial internal control and various method of food analysis. Chemical and Biological Sensor are used for food quality monitoring as well as application of AI to provide best quality food products. Planning of ordinary reliable procedures to regulate the standard of products may be a major objective. Despite these obstacles, research into optimizing production processes using AI is ongoing. It is crucial to emphasize, however, that the benefit of AI application in the food industry far outweigh the limitations.
Using narrative inquiry to explore the use of tasks in a Japanese language beginner course at university, Teacher research for English language teacher professional development: a three-level analysis of narratives
Authors: Nishikawa Yoshie , Pham An
Published: September 2022

Using narrative inquiry to explore the use of tasks in a Japanese language beginner course at university

In this talk I report on an action research study into how a Japanese language teacher experienced the transition from structure-based instruction to teaching with tasks. The study was situated in a course for beginner learners of Japanese at a university in New Zealand. I, the teacher-researcher, collected data on the experience of planning and teaching with tasks each week over ten weeks of a 12-week course. Weekly data included the teacher’s reflective journals, student survey data collected after each class, focus group data, and audio recordings of task-based interactions in class. Data from these sources was synthesised and analysed as narratives and presented as retrospective weekly stories. The paper reports on data from weeks 3 and 4 and focuses on the ways in which the teacher and students made sense of the task feature of learners needing to rely mainly on their own linguistic and non-linguistic resources, a task feature that is often perceived most difficult to put into practice by language teachers. Findings show how the teacher underestimated the students’ resilience and willingness to ‘have a go’ at performing challenging communicative tasks and the insights and strategies the teacher developed through the research.
A VISIT OF NICOLAE IORGA TO KRAKOW IN 1924
Authors:   Adam Mickiewicz University of Poznań, Faculty of Pedagogy and Arts in Kalisz, 62-800 Kalisz, ul. Nowy Świat 28/30, Poland,, Gołdyn Piotr
Published: September 2022

In June 1924, a scholar and Romanian politician, Professor Nicolae Iorga, visited several Polish cities. Some fragmentary materials relating to the organisation of this visit to Krakow were preserved in the archives of the Jagiellonian University. This task was assigned to the university authorities by the Ministry of Foreign Affairs. In order to provide a reasonably detailed description of this visit to Krakow, the preserved source material as well as press reports from popular newspapers published in this city at the time were analysed. Above all, the analysis was of a qualitative nature. This led to elaboration of a study which illustrates the circumstances of Nicolae Iorga’s visit to Krakow and the course of his stay. It also serves as a starting point for similar considerations with regard to other Polish cities - Warsaw, Vilnius, Poznan and Lviv - which were also visited by Nicolae Iorga at the time.
A SHORT HISTORY OF PANDEMICS
Authors:   University of Medicine and Pharmacy of Craiova, Ionescu Alin Gabriel , Ionescu Mihaela ,   University of Medicine and Pharmacy of Craiova, Glodeanu Adina Dorina ,   University of Medicine and Pharmacy of Craiova, Sas Teodor Nicusor ,   University of Medicine and Pharmacy of Craiova, Vere Cristin Constantin
Published: September 2022

Humanity is constantly being exposed to numerous infectious agents, and proof exists since ancient times. Various viruses, bacteria, fungus or parasites affect all living species and may cause sickness, by triggering reactions of the host tissues to them and to the toxins they produce. Following a process of natural selection, humans have adapted by active infection and developed natural immunity which, in some cases, may be transmitted from breast milk as passive immunity. Pandemics are defined as the rapid spread of an infectious disease over a wide region, several continents or worldwide, affecting a substantial number of humans in a short period of time. The first attempts to fight pandemics were represented by empirical treatments; nowadays, technology and science are our closest allies, with vaccines, modern medication and proper follow-up. Still, the lack of education, a potential distrust in science and beliefs in superstitions of their peers remains the most difficult obstacle to overcome in the fight against pandemics. It is certain that other pandemics will come again, and humanity must always be prepared to fight them, therefore it is very important to invest in science and education, in order to emerge victorious in the following battles.
"Sequential Volumetric Modulated Arc Therapy (VMAT) Boost in Hy- brid Plan With Tangential Beams for Whole Breast Treatment: a Do- simetric Study "
Authors:   UO Radioterapia Oncologica, Villa Santa Teresa, Bagheria, Palermo, Piras Antonio , Boldrini Luca ,   UOC Radioterapia Oncologica - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Di-partimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Roma, D'Aviero Andrea ,   Radiation Oncology, Mater Olbia Hospital, Olbia, Sassari, Italy, Sanfratello Antonella ,   Università degli Studi di Palermo, Radioterapia Oncologica, Palermo, Menna Sebastiano ,   UOC Radioterapia Oncologica - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Di-partimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Roma, Massaccesi Mariangela ,   UOC Radioterapia Oncologica - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Di-partimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Roma, Spada Massimiliano ,   UO Oncologia, Fondazione Istituto G. Giglio, Cefalù, Palermo, Pernice Gianfranco ,   UO Oncologia, Fondazione Istituto G. Giglio, Cefalù, Palermo, Angileri Tommaso ,   UO Radiologia, Villa Santa Teresa, Bagheria, Palermo, Daidone Antonino ,   UO Radioterapia Oncologica, Villa Santa Teresa, Bagheria, Palermo
Published: September 2022

"Purpose: Whole breast radiation therapy (WBRT) with a boost to the tumor bed following con-servative primary surgery in women with breast cancer (BC) plays a central role in reducing local recurrences and mortality. Volumetric modulated arc therapy (VMAT) technique has been shown to allow better dose conformation with low dose levels to organs at risk (OARs), compared to static fields three-dimensional Conformal Radiotherapy (3D-CRT). The aim of this study was to evaluate the feasibility and dosimetric advantages of sequential boost (SB), administered with VMAT tech-nique in hybrid plans with tangential beams for whole breast treatment. Material and methods: BC patients undergoing adjuvant RT from June to October 2020 were selected. ESTRO guidelines for the Clinical Target Volume (CTV) delineation were used. Total delivered dose was 60-66 Gy; 50 Gy in 2 Gy daily fractions for whole breast and 10-16 in 2 Gy daily fractions Gy to tumor bed was 10-16 Gy in 2 Gy daily fractions. Results: The analysis included 31 patients with BC treated with adjuvant RT following con-servative surgery. Hybrid treatment plans characterized by a 3D-CRT plan using tangential medi-olateral and lateromedial fields for the irradiation of the whole breast Planning Target Volume (PTV) and a sequential VMAT plan with 2 coplanar arches for boost PTV irradiation were gener-ated. Dosimetric analysis resulted in homogeneous target volumes coverage and OARs constraints compliance. As regarding to organs at risks (OARs), contralateral breast, ipsi- and contralateral lung and heart constraints values were analysed. Conclusions: In the frame BC RT, this dosimetric study showed that hybrid plans performed with 3D-CRT and VMAT techniques are feasible in terms of dosimetric outcomes. "
Real-World Treatment Patterns and Recurrence Rates in Cutaneous Melanoma Patients – Single Romanian Center Experience
Authors:   Department of Oncology, Neolife Medical Center, Bucharest, Romania, Jinga Dan Corneliu , Lazăr Ioana ,   Department of Oncology, Neolife Medical Center, Bucharest, Romania, Jinga Maria-Ruxandra ,   Medical School, Newcastle University, Newcastle upon Tyne, UK, Crăciunescu Andrea ,   Department of Oncology, Neolife Medical Center, Bucharest, Romania
Published: September 2022

"Introduction. Cutaneous melanoma is one of the deadliest cancers, and its incidence has dramatically increased over the last 20 years. Its mortality has decreased slightly worldwide over the past 10 years, largely due to new approaches such as sentinel node biopsy and new systemic treatments. Materials and method. This retrospective study comprises 151 cases of cutaneous melanoma (stages 0, I, II, and III) diagnosed between 2003 and 2019 in Romanian patients at a single center. It provides epidemiological information (stage at diagnosis, histological aspects, status of BRAF mutation, pattern of recurrence) and shows survival parameters associated with systemic adjuvant treatments and first and second-line therapies for recurrence. Results. Compared to other European countries, Romanian patients with cutaneous melanomas have different characteristics: younger age (50 years median age at diagnosis), more advanced stages (70% for male and 44% for female patients), and BRAF mutation in 70% of cases. More than 50% of the patients with stages IIB, IIC, and III received adjuvant IFN-α2b after complete resection. However, there were similar outcomes in terms of median disease-free survival (DFS) (33.46 months for the entire cohort) independently of adjuvant systemic treatments administered in the interferon alpha-2b era. The 3-year DFS and OS rates for stages IIB and IIC were similar to those of stage III. The prognosis was worse for BRAF mutated melanoma in terms of DFS and OS, independently of clinical stages. Conclusion. Our study demonstrates that stages IIB and IIC have the same pattern of recurrence and similar outcomes to those of stage III and could benefit from adjuvant systemic treatment as shown in KEYNOTE-716 clinical study."