bluuebunny/crossref_metadata_2025 huggingface dataset:
Peran Pengkaji Hadis dalam Menjaga Eksistensi Sunnah
Authors: Munadi Radhie
Published: March 2023

The problem of Hadith, if parsed, includes many things, from the authenticity of which many orientalists have been challenged, to expanding to transmission (isnad), the history of changing the verbal tradition in codification into hadith texts, to problem understanding and meaning. This problem occupies an important position as well as substantively giving spirit, reevaluation and reinterpretation of various understandings and interpretations of hadith, including differences in the practice of a hadith. So the role of hadith reviewers is needed so that from maintaining the integrity of the hadith to the level of practice, the hadith or sunnah is maintained. So this research tries to provide scientific treasures in an effort to maintain the existence of the sunnah.
Model Perencanaan Hidup Seorang Muslim
Authors: Kaslam Kaslam
Published: March 2023

Ketika seseorang meyakini bahwa dirinya akan menjadi tua, maka ia akan melakukan perencanaan hidup. Banyak hal yang akan ditempuh untuk mempersiapkan hari tua seperti investasi usaha, asuransi kesehatan, asuransi pendidikan, tabungan hari tua dan sebagainya. Hal tersebut dilakukan karena semata-mata sadar bahwa fisiknya pasti akan lemah, tidak selamanya akan sehat dan suatu saat menjadi tua. Artikel ini mengurai bagaimana seseorang muslim dalam melakukan perencanaan hidup dalam islam yang berbasis pada Al Qur’an dan Hadis Nabi. Konsep perencanaan hidup ditemukan dalam Surah Hasyr:18 yang menuntut seorang muslim hendaknya senantiasa memperhatikan apa yang dikerjakan untuk hari esok (akhirat). Maknanya bahwa dalam merencanakan hidup hendaknya tidak memisahkan antara kehidupan dunia dan akhirat. Akan ada kehidupan akhirat yang juga harus direncanakan, agar hidup didunia lebih bermakna dan produktif. Dalam Hadis juga disebutkan bahwa setidaknya ada empat hal yang diaudit pada hari akhirat nanti dan hal ini bisa menjadi pedoman dalam merencanakan hidup. Keempat hal tersebut  yaitu usia digunakan untuk apa; fisiknya dihabiskan untuk apa, finansial didapatkan dari mana dan kemana didistribusikan; dan pengetahuan yang dimiliki, sejauh mana diamalkan. Hal ini sangat penting untuk menjadi renungan dalam merencanakan hidup agar bisa sukses di dunia dan di akhirat.
Pemanfaatan Media Sosial untuk Berdakwah
Authors: HANANTO PRADITYA MER
Published: March 2023

Abstrak:Indonesia sebagai negara keempat berpopulasi terbanyak di dunia memiliki penganut agama Islam sebanyak 87%, pengguna internet aktif sebanyak 73%, pengguna media sosial sebanyak 61% dan menggunakan telepon genggam untuk akses internet sebanyak 125%. Kondisi ini ideal untuk berdakwah menggunakan media sosial dalam upaya mencapai pasar umat. Contoh pendakwah yang diambil adalah influencer Felix Siauw yang memiliki keunikan sendiri dalam pemanfatan atribut yang ia miliki.Kata Kunci: Media Sosial, Dakwah, Felix Siauw Abstract:Indonesia as fourth largest population country in the world had 87% Islam’s believers, 73% active internet users, 61% social media users and 125% mobile phone users to access internet. This condition is ideal to do a da’wah (preaching in Islamic term) using social media as a way to get believer market. The preacher used as example is an influencer Felix Siauw who have his uniqueness utilising his own attribute.Key Words: Social Media, Da’wah, Felix Siauw
IMPLEMENTASI NILAI-NILAI TOLERANSI UMAT BERGAMA PADA UPACARA RAMBU SOLO DI TANA TORAJA
Authors: Aulia Guruh Ryan , NAWAS SITTI SYAKIRAH ABU
Published: March 2023

Abstrak;Keragaman Indonesia sesuatu yang tidak dapat dipungkiri keberadaannya. Konteks pemahaman masyarakat majemuk, selain kebudayaan kelompok suku bangsa, masyarakat Indonesia juga terdiri dari berbagai kebudayaan daerah yang bersifat kewilayahan yang merupakan pertemuan dari berbagai kebudayaan kelompok suku bangsa yang ada di daerah tersebut. Dalam keberagamannya Indonesia wajib menjunjung tinggi nilai-nilai Toleransi umat beragama. Penelitian ini bertujuan untuk mengetahui implementasi Nilai-nilai Toleransi Umat Beragama pada Upacara Rambu Solo di Tana Toraja. Penelitian ini menggunakan metode penelitian kualitatif dengan menggunakan teknik analisis Komparasi Konstan (Constant Comparative Analysis) yaitu peneliti berusaha mengkonsentrasikan dirinya pada deskripsi yang rinci tentang sifat dan ciri dari data yang sudah dikumpulkan, sebelum berusaha menghasilkan pernyataan-pernyataan teoretis yang lebih umum. Berdasarkan hasil penelitian menunjukkan bahwa Tahapan upacara adat Rambu Solo, antara lain : Ma’mulai atau pembukaan, Mattarima tamu atau menerima tamu, Ma’sandu, Mantunu tedong, Istirahat (rehad), Makpeliang atau Penguburan. Implementasi Nilai – nilai Toleransi Umat Beragama pada Generasi Milineal yaitu Tidak membeda-bedakan setiap masyarakat atau generasi milineal, Mengizinkan berdoa sesuai dengan keyakinan masing-masing, Mengingatkan untuk senantiasa melaksanakan ibadah sholat maupun puasa bagi yang beragama IslamKata Kunci;Implementasi , Nilai-Nilai Toleransi Umat Beragama, Rambu SoloAbstractThe diversity of Indonesia is something that cannot be denied. The context of understanding a pluralistic society, in addition to the culture of ethnic groups, Indonesian society also consists of various regional cultures which are a meeting of various cultures of ethnic groups in the area. In its diversity, Indonesia is obliged to uphold the values of religious tolerance. This study aims to determine the implementation of Religious Tolerance Values at the Solo Sign Ceremony in Tana Toraja. This study uses qualitative research methods using Constant Comparative Analysis, where the researcher tries to concentrate on a detailed description of the nature and characteristics of the data that has been collected, before trying to produce more general theoretical statements. Based on the results of the study, it shows that the stages of the Rambu Solo traditional ceremony, among others: Ma'mulai or opening, Mattarima guests or receiving guests, Ma'sandu, Mantunu tedong, Rest (rehad), Makpeliang or Burial. Implementation of Religious Tolerance Values in the Millennial Generation, namely Not discriminating against every community or millennial generation, Allowing praying according to their respective beliefs, Reminding to always carry out prayers and fasting for Muslims.Keyword;Implementation of Religious Tolerance Values, Solo Signs
Berjabat Tangan dalam Perspektif Hadis (Suatu Kajian Maanil Hadis)
Authors: Munadi Radhie
Published: March 2023

Dalam membentuk sebuah kondisi yang kondusif melalui bersalaman atau berjabat tangan bahwa manusia bersalaman mempunyai beberapa maksud: pertama, untuk meminta maaf atas kesalahan yang dia lakukan. Kedua, sebagai tanda sebuah persahabatan. ketiga, karena mereka sudah lama tak jumpa. Keempat, untuk mempererat silaturrahmi. Maka dari itu kalau jika ingin semakin kuat persatuan dan semakin kokoh pebanyaklah bersalaman.Bersalaman (Musa>fahah) bukan adat tetapi, anjuran dari Nabi Muhammad saw., yang mana balasannya akan diampuni dosa-dosa sebelum berpisah. Penelitian ini memilih kitab Sunan Abu> Da>wud karena kitab tersebut salah satu dari Kutub al-Sittah yang pasti menjadi rujukan pertama untuk mencari hadis selain S{ah}i>h} al-Bukha>ri dan S{ah}i>h} Muslim serta menurut para ulama termasuk urutan nomor tiga tingkat keshah}ih}an serta keh}ujjahannya. Penelitian ini mencoba memberikan khazanah baru terhadap makna bersalaman itu sendiri dengan pendekatan ma’ani al-hadisKata Kunci: Ma’ani al-Hadis, Perspektif Hadis, Berjabat TanganIn establishing a conducive condition through shaking hands that humans shake has several purposes: first, to apologize for the mistakes he has made. Second, as a sign of friendship. third, because they haven't seen each other for a long time. Fourth, to strengthen friendship. Therefore, if you want to get stronger and stronger, shake hands.               Shaking hands or Musafahah is not a custom, but a recommendation from the Prophet Muhammad, in which sins will be forgiven before parting. This study chose the book Sunan Abu Dawud because the book is one of the Kutub al-Sittah which must be the first reference to look for hadith other than Sahih al-Bukhari and Sahih Muslims and according to the scholars including the number three level of authenticity.This study tries to provide a new treasure for the meaning of shaking hands it self with the ma'ani al-hadith.Keywords: Ma’ani al-Hadis, hadith perspective, shaking hands
Kajian Otentisitas Hadis Dalam Pandangan Mustafa Ali Yaqub
Authors: Wangsa Fadhlina Arief , Ramadhan Muhammad
Published: March 2023

Artikel ini membahas tentang cara membuktikan keotentikan hadis yang berasal dari nabi muhammad saw. Dalam tulisan ini ada lima hal yang menjadi pembahasan inti yaitu pertama tentang sosok mustafa ali yaqub, kedua tentang hadis dan sunnah, ketiga tentang otentisitas hadis, keempat tentang kritik hadis, dan yang kelima tentang otoritas sebuah hadis. Tulisan ini dibuat lantaran banyak pandangan yang meragukan bahwa hadis berasal dari nabi terutama para orientalis. Hal ini tentunya berbahaya apabila tidak diberikan pemahaman yang utuh tentang hadis terutama pada orang awam. Oleh karena itu, untuk menangkal hal tersebut maka perlu diketahui bagaimana cara membuktikan keotentikan suatu hadis. Dengan melakukan kajian pustaka dan kajian tokoh hadis indonesia yaitu mustafa ali yaqub untuk menambah wawasan tentang kajian hadis terutama di indonesia. maka artikel ini menyimpulkan bahwa cara membuktikan keotentikan hadis itu ada dua hal yang perlu dilakukan yaitu memahami hadis secara utuh dan melakukan kririk hadis.
PEMIKIRAN IBN HAZM: MAZHAB ZHAHIRI DAN FILSAFAT
Authors: Wangsa Fadhlina Arief , Rayyn I Gusti Bagus Agung Perdana
Published: March 2023

Artikel ini membahas tentang biografi dan pemikiran Ibn Hazm sebagai seorang ulama fikih dan filsafat yang berasal dari Andalusia, Spanyol. Dalam artikel ini terdapat tiga hal penting yang menjadi pembahasan inti yaitu, pertama terkait biografi Ibn Hazm dan karya-karyanya, kedua pemikiran beliau secara umum tentang fikih, khusunya yang berkaitan dengan mazhab zhahiri, dan yang ketiga adalah pemikiran beliau tentang filsafat dalam hal proses penciptaan alam semesta. Oleh karena itu, maka perlu kiranya untuk memaparkan hal-hal tersebut agar tidak menimbulkan salah persepsi dengan melakukan kajian pustaka dan kajian tokoh untuk menambah wawasan tentang pemikiran ulama, Maka kesimpulannya adalah bahwa yang dapat dijadikan dalil hukum hanya Al Quran, hadis, dan ijma’. Sedangkan penciptaan alam semesta berasal dari ketidakadaan.
Tahlili Hadis,
Authors: Munadi Radhie
Published: March 2023

In everyday life, the term bribery is no stranger to hearing. Day after day bribery cases are often found in several media. However, it is often found that only the briber is at fault. Whereas in the explanation of muhaddistin scholars, there are 4 elements in bribery, namely the briber, the recipient of the bribe, the intermediary of the bribe and the treasure of the bribe.

Explanations related to some of these elements are obtained by several approaches, one of which is tahlili hadith. Bribery in a hadith perspective with a tahlili approach is needed so that the understanding of the bribery hadith is more detailed and clear. In fact, all these elements are cursed and kept away from goodness.

This study tries to provide a new scientific treasure in the content of hadith to understand bribery with the tahlili hadith approach.

Keywords:

Hadith, Bribery, Tahlili
TOLERANSI ANTAR UMAT BERAGAMA DALAM PERAYAAN LOVELY DESEMBER DI TANA TORAJA
Authors: Aulia Guruh Ryan
Published: March 2023

Artikel ini membahas mengenai toleransi antar umat beragama dalam perayaan lovely desember di Tana Toraja. Pelaksanaan perayaan lovely desember ini terdapat beberapa kegiatan yaitu ; Festival karnaval tedong, festival kopi, festival qasidah, festival kuliner, festival tandem paralayang, festival drama musikal atau sendratari, festival ekonomi kreatif, festival paduan suara, festival ring road Christmas advanture toraja, perayaan natal oikumene, dan festival kembang api. Perayaan lovely desember memiliki manfaat dalam mempererat hubungan persaudaraan dalam masyarakat. Pelaksanaan kegiatan tersebut merupakan contoh nyata kerjasama yang dilakukan antar umat beragama dalam terlaksananya kegiatan tersebut serta menunjukkan sikap toleransi antar umat beragama di Tana Toraja. Unsur-unsur dalam mewujudkan toleransi antar umat Bergama yaitu ; saling membantu dalam terlaksana kegiatan besar di Toraja, Kebudayaan yang di junjung tinggi, pemerintah yang bertindak aktif dalam meningkatkan toleransi antar umat beragama, keinginan untuk memajukan kota toraja
QAWAID AL-TAHDIS DALAM TINJAUAN HISTORIS
Authors: Ali Muhammad , Husni Fajril
Published: March 2023

Artikel ini membahas tentang sejarah, ruang lingkup dan urgensi Qawaid al-Tahdis. Dalam artikel ini terdapat beberapa hal penting yang akan menjadi inti bahasan yaitu, Pengertian Qawaid al-Tahdis, sejarah perkembangan dan pertumbuhan Qawaid al-Tahdis dari berbagai perspektif ulama, ruang lingkup Qawaid al-Tahdis beserta urgensinya. Oleh karena itu maka perlu kiranya menjelaskan hal-hal tersebut agar tidak menimbulkan kekeliruan dan kesalahpahaman dalam memahami terkait dengan historitas Qawaid al-Tahdis. Pengkajian masalah ini dilakukan dengan cara melakukan kajian pustaka dengan pendekatan historis. Maka kesimpulannya adalah qawaid al-tahdis adalah ilmu yang mempelajari terkait dengan kaidah-kaidah dalam keilmuan hadis. Dalam perkembangannya, qawaid al-tahdis dalam aspek kesejarahan terjadi perbedaan pendapat dikalangan pengkaji hadis terkait dengan priodesasi perkembangan hadis. Bahasan dalam qawaid al-tahdis mencakup pengkajian dari segi autentisitas hadis Nabi saw. Qawaid al-tahdis menjadi keilmuan yang penting karena terjadinya banyak distorsi terhadap hadis Nabi saw. sehingga menjadi sebuah pisau analisis dalam pengkajian hadis.
TASYAHUD AKHIR; KAJIAN TEKS HADIS RASULULLAH SAW
Authors: Fadhlina Arief Wangsa  , Nurul Iqram Asdar
Published: March 2023

Most of the verses of the Qur'an in tafshili (detail) need to be explained with hadith, such as the command to pray by looking at the hadith from the Prophet Muhammad, the pillars of prayer, one of which is sitting at the final tasyahud. This research is a library research, by collecting related literature, then it is presented in a qualitative descriptive manner, namely displaying the data as it is. Based on the hadith of the Prophet about the final tasyahud sitting provides an understanding that there are various views regarding the reading and the final tasyahud sitting position in prayer. it is obligatory during the recitation of tahiat to say salam to us and to the authentic servants of Allah. The last sitting in the prayer is done with iftirosy or Tawarruk. Various kinds of tahiat pronunciations included in the hadith can also be practiced.
PELAKSANAAN SANKSI PIDANA PEMBAYARAN UANG PENGGANTI TERHADAP KORPORASI DALAM TINDAK PIDANA KORUPSI
Authors: Siregar Deny setiawan , Ablisar Madiasa , Yunara Edi
Published: March 2023

Dalam praktik penegakan hukum di tanah air, penegak hukum khususnya Hakim masih belum memberikan putusan yang tepat yaitu adanya ketimpangan antara aspek hukum yang diharapkan (das sollen) dengan aspek penerapan hukum yang ada di masyarakat (das sein), sehingga menimbulkan persoalan terkait penentuan pertanggungjawaban pidana terdakwa yang dapat juga dikenakan kepada korporasi serta ketidakjelasan tujuan pembayaran uang pengganti, apakah untuk merampas harta hasil korupsi atau untuk mengganti kerugian negara. Metode penelitian yang digunakan penelitian hukum normatif, dimana penelitian ini berupaya untuk memberikan argumentasi dari hasil penelitian yang telah dilakukan. Hasil penelitian disimpulkan bahwa Mahkamah Agung R.I. dan Kejaksaan Agung R.I. membuat peraturan yang dapat menjadi pedoman bagi penegak hukum dalam menentukan pertanggungjawaban pidana korporasi serta menentukan jumlah pembayaran uang pengganti yaitu sebanyak-banyaknya sama dengan harta benda yang diperoleh dari tindak pidana korupsi dan bukan semata-mata sejumlah kerugian negara yang diakibatkan. Perlunya untuk melakukan pembaruan KUHP dan KUHAP dengan menegaskan korporasi sebagai subjek hukum yang dapat dimintai pertanggungjawaban pidana, karena keberadaan Peraturan Mahkamah Agung R.I. dan Peraturan Jaksa Agung R.I. tersebut memiliki keterbatasan pengaturan penanggulangan tindak pidana yang dilakukan oleh korporasi yaitu dalam hal tertentu dilarang mengatur lebih dari yang telah ditetapkan oleh Undang-Undang.

Kata Kunci;

Pertanggungjawaban pidana korporasi, pidana tambahan berupa pembayaran uang pengganti, tindak pidana korupsi
Clinical experience with next-generation sequencing–based liquid biopsy testing for cancer detection in dogs: a review of 1,500 consecutive clinical cases
Authors: O’Kell Allison L. , Lytle Katherine M. , Cohen Todd A. , Wong Lilian K. , Sandford Emily , Rafalko Jill M. , Brandstetter Gina , DiMarzio Lauren R. , Phelps-Dunn Ashley , Rosentel Michelle C. , Warren Chelsea D. , McCleary-Wheeler Angela L. , Fiaux Patrick C. , Marass Francesco , Marshall Maggie A. , Ruiz-Perez Carlos A. , Kruglyak Kristina M. , Tynan John A. , Hicks Susan C. , Grosu Daniel S. , Chibuk Jason , Chorny Ilya , Tsui Dana W. Y. , Flory Andi
Published: March 2023

OBJECTIVE

To review ordering patterns, positivity rates, and outcome data for a subset of consecutive samples submitted for a commercially available, blood-based multicancer early-detection liquid biopsy test for dogs using next-generation sequencing at 1 laboratory.

SAMPLE

1,500 consecutively submitted blood samples from client-owned dogs with and without clinical suspicion and/or history of cancer for prospective liquid biopsy testing between December 28, 2021, and June 28, 2022.

PROCEDURES

We performed a retrospective observational study, reviewing data from 1,500 consecutive clinical samples submitted for liquid biopsy testing. Outcome data were obtained via medical record review, direct communication with the referring clinic, and/or a patient outcome survey through October 16, 2022.

RESULTS

Sixty-four percent (910/1,419) of reportable samples were submitted for cancer screening, 26% (366/1,419) for aid in diagnosis, and 10% (143/1,419) for other indications. The positivity rate was 25.4% (93/366) in aid-in-diagnosis patients and 4.5% (41/910) in screening patients. Outcome data were available for 33% (465/1,401) of patients, and outcomes were classifiable for 428 patients. The relative observed sensitivity was 61.5% (67/109) and specificity was 97.5% (311/319). The positive predictive value was 75.0% (21/28) for screening patients and 97.7% (43/44) for aid-in-diagnosis patients, and the time to diagnostic resolution following a positive result was < 2 weeks in most cases.

CLINICAL RELEVANCE

Liquid biopsy using next-generation sequencing represents a novel tool for noninvasive detection of cancer in dogs. Real-world clinical performance meets or exceeds expectations established in the test’s clinical validation study.
Citrullinemia is a suitable biomarker for post weaning performance in piglets under intensive farming
Authors: Soraci Alejandro L. , Decundo Julieta M. , Dieguez Susana N. , Martínez Guadalupe , Pérez Gaudio Denisa S. , Amanto Fabián A.
Published: March 2023

OBJECTIVE

To describe citrullinemia profiles during the weaning transition and correlate citrulline production with stress and growth in a commercial pig farm.

ANIMALS

240 healthy piglets of homogenous weight, weaned from second and third parity sows, were selected at weaning and subjected to the farm’s routine management practices in May to July 2020 and May to July 2021.

PROCEDURES

Piglets were weighed at weaning, then 15 and 49 days later in order to calculate daily weight gain during the first 15 and 49 days after weaning. Blood samples were collected from each piglet to determine citrulline and cortisol profiles during the early postweaning period.

RESULTS

Citrullinemia decreased dramatically during the first week postweaning and then increased progressively to reach preweaning values by 15 days postweaning. Citrulline production during the first 2 weeks postweaning was negatively correlated with cortisol production (r: –0.2949) and positively correlated with mean daily weight gain during the first 15 (ρ: 0.5450) and 49 (ρ: 0.6603) days postweaning.

CLINICAL RELEVANCE

Citrullinemia profile of piglets during the early postweaning period showed a temporal negative impact of stress (assessed by plasmatic cortisol levels) on intestinal enterocytes’ mass and function, which resulted in a lower average daily weight gain. We demonstrated that a single biomarker, plasmatic citrulline, is useful to describe intestinal metabolism during the early postweaning period and that the greater the citrulline production during the first days after weaning, the higher the weight gain during the entire postweaning period.
Highly Similar Average Collateral Effect of Synonymous Mutations Across Alternative Reading Frames: A Potential Role In Evolvability
Authors: Wichmann Stefan , Ardern Zachary
Published: March 2023

Synonymous mutations in a protein coding gene lead to a remarkably similar average “collateral” mutation effect size across alternative reading frames (1). Here we quantify the rarity of this feature among possible block structure codes as 0.77%. Then we develop a simple model of evolutionary search with two types of mutation. Across different mutation step sizes and ratios of the two types, the fitness-maximizing region corresponds to using a single average mutation value. The analogous constant average collateral mutation effect observed for the standard genetic code may likewise facilitate evolutionary search in alternative frame sequences.
Making Smart Things Strange Again: Using Walking as a Method for Studying Subjective Experiences of Smart City Surveillance
Authors: Butot Vivien , Jacobs Gabriele , Bayerl Petra Saskia , Amador Josué , Nabipour Pendar
Published: March 2023

Smart cities are commonly seen as places that are defined by surveillance because of their reliance on vast amounts of digital data to improve urban management challenges. Although the infrastructures and technologies that enable smart city surveillance pervade multitudinous urban spaces and everyday practices, they are often “hiding in plain sight,” going unnoticed in the bustle of everyday life. Hence, fostering research settings where citizens can productively reflect on their everyday surveillance constitutes a major challenge for the interrelated projects of doing empirical research about subjective experiences of smart city surveillance and the inclusion of citizens in smart city discussions. Drawing on walking as a method, this study attempts to meet this challenge by developing and empirically testing a methodology of purposive “data walking.” Situating the research in Rotterdam, the Netherlands, participants are instructed to identify data points for public safety purposes on a short walk through the city and reflect on their experiences. Observations and experiences of smart city surveillance are documented with photos, text descriptions, and audio notes, which are shared in real-time with researchers and provide the basis for group reflections. These walks and reflections generate rich visual and textual data that yield insights into embodied and situated constructions of smart city surveillance as an object of subjective inquiry, experiences of visibility, considerations of agency and evaluations of public safety implications. The study considers these empirical results in conjunction with reflections on the methodology, contributing to further methodological explorations for including citizens in smart city discussions and surveillance subjectivity research.
Neoplasia Maligna da Próstata e Fertilidade: Revisão das Implicações das Diferentes Opções Terapêuticas
Authors: Fonseca Rita , Mota Renato , Peyroteo I. , Santos J. C. , Silva Andreia , Gaspar Frederico , Abranches-Monteiro Luís
Published: March 2023

Introdução: A neoplasia maligna da próstata é a segunda neoplasia mais comum nos homens, e a sua incidência é mais elevada no grupo com 50-69 anos de idade. Estima-se que cerca de 5% dos casos sejam diagnosticados em homens com idade inferior a 50 anos. Dada a evolução demográfica actual, o desejo de paternidade é frequentemente adiado. Assim, é relevante que o urologista possa explicar as diferentes repercussões que as terapêuticas existentes para a neoplasia maligna da próstata têm na fertilidade masculina. O objectivo desta revisão é comparar o impacto que as diferentes opções terapêuticas existentes na neoplasia maligna da próstata têm na fertilidade masculina.
Métodos: Realização de revisão qualitativa da literatura publicada entre 1987-2019, de acordo com as orientações ENTREG e metodologia PRISMA, utilizando a base de dados PubMed. Foram considerados elegíveis todos os artigos sobre este tema escritos em inglês, incluindo estudos randomizados controlados, meta-análises e revisões sistemáticas. Todos os resumos foram lidos por dois autores com subsequente selecção daqueles que cumprissem os critérios definidos, após avaliação de qualidade utilizando a checklist qualitativa CASP. Em caso de discordância, um terceiro urologista foi consultado.
Resultados: De acordo com os critérios definidos, foram identificadas 436 referências e 10 publicações foram incluídas por se referirem directamente ao objectivo definido. Apesar da escassez de literatura publicada, é possível concluir que a vigilância activa não tem implicações na fertilidade. De acordo com os dados disponíveis, a terapêutica focal e a braquiterapia são as opções terapêuticas com menor probabilidade de provocar incapacidade permanente na fertilização por métodos naturais, em oposição a prostatectomia radical, radioterapia, hormonoterapia e quimioterapia.

Conclusão: Actualmente, com o aumento da sobrevivência após tratamento de cancro da próstata, é necessário avaliar as repercussões que as diferentes opções terapêuticas têm na fertilidade, de forma que os doentes possam fazer uma decisão informada e, se necessário, recorrer a estratégias de preservação de gâmetas. Apesar de não existirem estudos comparativos, a terapêutica focal e a braquiterapia parecem ter menor efeito deletério na fertilidade masculina. A vigilância activa é actualmente a única opção sem consequências na fertilidade.
DOCTOR'S PROFESSIONAL COMPETENCES IN TELEMEDICINE
Authors:   Research Institute for Healthcare Organization and Medical Management of Moscow Healthcare Department, Moscow, Russian Federation, AKSYONOVA E.I. , VVEDENSKIY A.I. ,   Department of Anatomy, I.P. Pavlov Ryazan State Medical University, Ryazan, Russian Federation
Published: March 2023

Objective: To analyse the professional skills forming the professional competence of a doctor providing medical care in the field of telemedicine. Methods: The following research methods were used: secondary analysis of sociological research data from Russian analytical agencies and the author's medico-sociological research on the topic "Telemedicine in the daily professional activity of a doctor." The analysis was carried out by the method of questionnaires and semi-structured interviews. The total sample size was 100 respondents; the study period is October 2021. Results: The study results showed a relatively high level of medical specialists' preparedness to use telecommunication technologies in their professional activities. Telehealth skills are necessary for a more accurate diagnosis, correct use of medical equipment, etc. According to the respondents, the primary way of telemedicine skills mastering is training from medical equipment suppliers, self-education and refresher courses initiated by the employer. In addition, a modern doctor needs to master "soft skills", which include operational thinking, multitasking and multiskilfulness, autonomy, communication skills, multilingualism and multiculturalism, creativity. Conclusion: Telemedicine and personalised medicine in Russia and globally are opening up a new frontier for the medical industry development. Therefore, a teledoctor, in addition to essential universal and general professional skills, should have new eHealth technology competencies. Keywords: Professional competence, medical care, telemedicine, information technology, online consultations, professional activity, skills.
COMPARATIVE CLINICAL AND PHARMACOECONOMIC ANALYSIS OF THE EFFICACY OF MODERN COMBINATION THERAPY IN PATIENTS WITH PRIMARY KNEE OSTEOARTHRITIS, STAGES I-III
Authors:   Department of Propedeutics of Internal Diseases, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, DAVLATZODA A.D. , SAIDOV YO.U. ,   Department of Propedeutics of Internal Diseases, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, MAKHMUDOV KH.R. ,   Department of Propedeutics of Internal Diseases, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, JAMOLOVA R.J. ,   Department of Internal Medicine № 3, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: March 2023

Objective: To study and comparatively evaluate the clinical and cost-effectiveness of modern structure/disease modifying anti- osteoarthritis drugs (S/ DMOADs) and hyaluronic acid (HLA) in modern intensive treatment of the primary knee osteoarthritis (KOA), stages I-III. Methods: A comparative clinical and pharmacoeconomic analysis (PEA) of the effectiveness of a 6-month course of modern S/DMOADs (Structum®, Artra®) in combination with intra-articular HLA preparations (Ostenil®) and symptom-modifying drugs (SMDs) including non-steroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids (GCs) was conducted in 103 patients with primary KOA, stages I-III. Results: At the end of the study (after 6 months), in patients with primary KOA, stages I-III, a statistically significant improvement in all clinical, laboratory and instrumental parameters reflecting the severity and activity of the disease was verified. The gains were most clearly observed in patients with early stages of KOA (I-II). Conclusion: Treatment with modern S/DMOADs (Structum®, Artra®) and HLA preparations (Ostenil®) and, symptomatically with (NSAIDs and GCs intraarticularly) in primary KOA patients, I-III stages demonstrates positive changes in all clinical and laboratory parameters (mainly in early stages of the disease). In addition, and no less critical, it considerably limits the use of NSAIDs. Therefore, treatment with Structum® of patients with early primary KOA is the most cost-effective. Keywords: Primary osteoarthritis, knee joints, pharmacoeconomic analysis, Structum®, Artra®, Ostenil®, WOMAC index.
ELECTRON MICROSCOPIC PROPERTIES OF A NEW ANTIMICROBIAL NANODRUG BASED ON COPPER-CALCIUM HYDROXIDE COMPOUND
Authors:   Department of Periodontology, Tver State Medical University, Tver, Russian Federation, RUMYANTSEV V.A. , FROLOV G.A. ,   Department of Physical Chemistry, National University of Science and Technology "MIS iS", Moscow, Russian Federation, BLINOVA A.V. ,   Department of Periodontology, Tver State Medical University, Tver, Russian Federation, KARASENKOV YA.N. ,   "RosDent" Medical Company, Moscow, Russian Federation, BITYUKOVA E.V. ,   Department of Periodontology, Tver State Medical University, Tver, Russian Federation
Published: March 2023

Objective: To study the structural arrangement of the copper-calcium hydroxide (CCH), a commercially available dental paste used in aqueous suspension, as well as a new antimicrobial nanodrug based on CCH and a hydrosol of copper nanoparticles and copper (II) oxide. Methods: Dental paste Cupral® manufactured by "Humanchemie GmbH" (Germany) was investigated. Immediately prior to the study, it was diluted with either distilled water or a hydrosol of copper nanoparticles and copper (II) oxide in a ratio of 1:2. The hydrosol was obtained in the Department of Physical Chemistry laboratory at the National University of Science and Technology "MISiS", using the method of condensation of low-temperature plasma in a spark discharge. The microstructure of the obtained samples was analyzed using a transmission electron microscope (TEM), LEO 912 AB OMEGA (Carl Zeiss, Oberkochen, Germany). Results: Dilution of CCH with a hydrosol of copper nanoparticles and copper (II) oxide results in forming a complex nanosized composite structure. Nanoparticles in the dispersed phase penetrate the surface layers of CCH particles, which are crystalline hydrates of copper (II) oxide and calcium oxide. Conclusion: The discovered phenomenon could be helpful in the design of a new technology of nanoimpregnation of the tooth root dentin in endodontic and periodontal treatment, which does not require additional electrophoresis. Keywords: Endodontics, periodontology, nanotechnology, copper-calcium hydroxide, electron microscopy.
RISK FACTORS AND CLINICAL MANIFESTATIONS OF LUNG MYCOBACTERIOSIS. SYSTEMATIC REVIEW
Authors:   Department of Fundamental Medicine, Mari State University, Yoshkar-Ola, Russian Federation, Amirova T.Kh. , PETROV I.V. ,   Department of Fundamental Medicine, Mari State University, Yoshkar-Ola, Russian Federation, RYZHOVA L.V. ,   Department of Biology, Mari State University, Yoshkar-Ola, Russian Federation, PETROVA F.S. ,   Department of Fundamental Medicine, Mari State University, Yoshkar-Ola, Russian Federation,   Bacteriological Laboratory, Republican Tuberculosis Dispensary, Yoshkar-Ola, Russian Federation, PETROVA L.V. ,   Department of Fundamental Medicine, Mari State University, Yoshkar-Ola, Russian Federation,   Bacteriological Laboratory, Republican Tuberculosis Dispensary, Yoshkar-Ola, Russian Federation, ALMUKHAMETOV A.A. ,   Department of Public Health and Healthcare Organization, Kazan State Medical University, Kazan, Russian Federation,   Scientific and Clinical Center for Precision and Regenerative Medicine, Kazan (Volga Region) Federal University, Kazan, Russian Federation
Published: March 2023

The present study is a systematic review with a meta-analysis of risk factors for lung mycobacteriosis (LM) and diseases that influence the incidence, clinical manifestations and etiology of the infection under investigation. The authors made a selection of papers. The search for papers was carried out in English and Russian in the PubMed, Web of Science, Сochrane Library, eLibrary electronic databases with the analysis of references from the articles found. Articles published from 2000 to 2020 were selected. The following results are obtained. Regarding smoking: with the two gradations of the factor (the patient smokes or not), the incidence of LM in smokers varied from 13.8±0.03% to 71.2±0.06%. Regarding tuberculosis: the incidence of LM and tuberculosis ranged from 6.7±0.01% to 17.6±0.02%. Regarding chronic obstructive pulmonary disease (COPD): the incidence of LM in patients with COPD was determined on average at 11.2±0.01%. Regarding bronchiectasis: the incidence of bronchiectasis in patients with LM is 30.1±0.02%. Regarding diabetes mellitus: the frequency of patients with LM and diabetes mellitus in one study group was 6.7±0.01%, and in the other – 17.6±0.02%. Regarding malignancies: the frequency of such patients was determined from 17.1±0.04% to 50.0±0.07% of cases. Regarding HIV infection and LM: the incidence of detected LM in patients with HIV was determined on average at the level of 8.9±0.01%. Regarding cough in LM: the frequency of patients with this symptom in the first group was 46.2±0.07%, in the second group – 88.9±0.02%. Regarding hemoptysis in LM: the frequency of patients with this symptom ranged from 3.8±0.03% to 30.1±0.02%. X-ray manifestations of lesions in LM occurred with a frequency of 42.3±0.04% to 100%. The most significant role in etiology belongs to non-tuberculous mycobacteria species, such as slow-growing M. avium complex, and fast-growing M. abscessus complex, M. chelonae, M. fortuitum. Keywords: Lung mycobacteriosis, nontuberculous mycobacteria, clinical manifestations, risk factors.
FOLATE METABOLISM IN PREGNANCY
Authors:   Department of Obstetrics and Gynecology № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, SALIMOVA Z.D. , DODKHOEVA M.F. ,   Department of Obstetrics and Gynecology № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: March 2023

The literature review examines the data on the role of folic acid in the human body, especially in women of the reproductive period. An analysis of research studies was conducted to assess the effect of folic acid and folate deficiency on organogenesis and placental formation. In addition, folate deficiency is associated with severe pregnancy complications, including placental abruption, spontaneous miscarriages, intrauterine growth retardation, and preeclampsia. Also, it plays a role in developing congenital malformations of the cardiovascular, nervous, visual and musculoskeletal systems. It was found that with hyperhomocysteinemia, the risk of complications with a self-enhancing cascade of pathological changes during the gestation period increases significantly. In this regard, when planning a pregnancy, it is recommended that all women examine the levels of homocysteine concentration. It is also mandatory to investigate the levels of homocysteine concentration in women with a history of obstetric complications – placental abruption, miscarriage, and the family history of stroke, myocardial infarction and thrombosis in relatives below the age of 45-50 years. Keywords: Folic acid, folates, folate deficiency, hyperhomocysteinemia, pregnancy, miscarriage.
José Luis Melgarejo Vivanco: Homenaje
Authors: Tejeda Martínez Adalberto , Corzo Ramírez Ricardo , Del Moral Tejeda Agustín , Ladrón de Guevara Sara
Published: March 2023

Figura central del mundo cultural veracruzano del siglo XX. Su labor personal y profesional, amplia y diversa, va de campos como la poesía y la ecología a la arqueología y la política, pasando por la educación y la creación de instituciones culturales clave en la vida de nuestro estado y, en general, del país. Su legado y sus aportaciones en estos terrenos siguen vigentes.
Percepción, riesgo y consumo de drogas en universitarios
Authors: De San Jorge-Cárdenas Xóchitl
Published: March 2023

PERCEPCION, RIESGO Y CONSUMO DE DROGAS EN UNIVERSITARIOS, en el que reconocidos académicos de la Universidad Veracruzana nos ofrecen un volumen rico en capítulos que analizan el consumo de sustancias legales e ilegales entre estudiantes universitarios y sus factores asociados. Las nuevas generaciones de jóvenes tienen significativamente más trastornos de ansiedad, abuso de sustancias y conductas disruptivas que los jóvenes de la misma edad de generaciones pasadas. Alrededor de las tres cuartas partes de los trastornos mentales y de la conducta inician antes de los 24 años. Sin embargo, pocos reciben tratamiento y los esfuerzos preventivos raramente se integran en el currículo cotidiano a pesar de que existen modelos efectivos de intervención.
Embrión Dorado
Authors: Harmodio Jorge
Published: March 2023

El codón de inicio de esta novela cuenta la clonación de un general de la Revolución mexicana. Insertadas aquí, como transposones de narrativa, hay varias historias: la de un programador y su translocación a escritor infectado por un virus computacional cuyo fenotipo es similar al de Francisco I. Madero; la de una bióloga que estudió en Edimburgo cultivando células de la glándula mamaria de una oveja genéticamente idéntica a Dolly; la gesta futbolística de un equipo de Durango en pos de la segunda división; la muerte de Pancho Villa y el proceso de gastrulación embrionaria. La narración transcurre durante un viaje por carretera, en donde el autor (XY) lee en voz alta a su acompañante (XX) una novela que escribió hace 23 años. EMBRIÓN DORADO es un texto complejo pero divertido, un organismo literario híbrido que derrocha sus posibilidades en una historia (in)coherente e (im)prudente, confiando en que, en la intimidad de la cognición lectora, su polifonía narrativa cristalice en un ser vivo que crezca, flote y se desarrolle en el líquido amniótico de la imaginación. La bióloga (XX) que suscribe no se hace responsable de las licencias poéticas que el autor (XY) se ha permitido tomar con los conceptos biológicos, embriológicos y genéticos.
Luz rebelde. Mujeres y producción cultural en el México posrevolucionario
Authors: Rashkin Elissa , Hernández Palacios Ester
Published: March 2023

El papel de las mujeres en el sector cultural mexicano sigue siendo, en gran parte, terreno desconocido, a pesar de un creciente corpus de investigación. Las mujeres más célebres del siglo XX, como Frida Kahlo, Tina Modotti, Nahui Olin o Nellie Campobello, no caben fácilmente en las historias escritas desde perspectivas masculinas; y, por cada una de ellas, existen otras cuya producción artística y literaria, en muchos casos atrevida e iconoclasta en su momento, ha caído en el olvido. Luz rebelde explora diversas facetas del paisaje que habitaban las creadoras en el México posrevolucionario, una época de conflicto, cambio y construcción. En este libro, seis investigadoras contemporáneas abordan los mundos creativos de seis figuras de la literatura y las artes: Concha Michel, Aurora Reyes, Concha Urquiza, Leonor Llach, Asunción Izquierdo Albiñana y Lola Cueto. El estudio de los aportes de estas autoras, cada una fascinante en sí, abre nuevos caminos para entender las múltiples maneras en que el estudio de las mujeres como agentes culturales cambia, necesariamente, el sentido de la historia cultural de México.
Narrativas de los sistemas estatales anticorrupción en México: Reflexiones desde lo local
Authors: Galindo José , Olvera Alberto
Published: March 2023

La corrupción es un problema grave que aqueja en mayor o en menor medida a todos los países del mundo. En el caso mexicano, el combate a la corrupción fue incluso el lema que acompañó el triunfo de Andrés Manuel López Obrador en las elecciones federales de 2018. Sin embargo, las políticas de combate a la corrupción aún distan mucho de generar los resultados esperados. En la actualidad, la implementación y el funcionamiento del Sistema Nacional Anticorrupción (SNA), creado en 2015, se han visto amenazados por políticas alternativas y personalistas planteadas por el nuevo gobierno federal; las cuales, además de no mostrar la efectividad requerida, debilitan toda la fase de creación institucional que implicó el Sistema Nacional y los sistemas locales Anticorrupción. En este libro se narran casos específicos sobre cómo se ha dado el proceso de implementación de los sistemas locales anticorrupción y cuáles son las problemáticas más comunes que enfrentan los estados en este trayecto, las cuales han causado que, en algunos casos, estos sistemas se encuentren en franco estancamiento. Asimismo, se narran aquí los retos actuales que enfrentan las administraciones estatales para lograr que sus sistemas sean la vía principal de combate a la corrupción, independientemente de la administración federal que se encuentre en el poder.
Matacapan: una ciudad del Clásico y su relación con Teotihuacán
Authors: Ortiz Ceballos Ponciano , S. Santley Robert
Published: March 2023

Teotihuacán (Valle de México) fue el primer gran centro urbano en Mesoamérica, una ciudad organizada y planificada perfectamente que pudo sostener un número considerable de población y que tuvo un control económico fuera de su región, cuya cultura, así como su poderío económico, influyeron en todos los confines. De esta manera, mantuvo enclaves en Kaminaljuyu y Tikal dentro del área maya en Guatemala. Matacapan, ciudad ubicada en Los Tuxtlas, Veracruz, representó el paso estratégico hacia esas localidades guatemaltecas mencionadas y, a juzgar por los datos, parece haber funcionado como un puesto de control de productos exóticos de interés teotihuacano y su intercambio a grandes distancias. El proyecto de Matacapan se origina en 1982 con la finalidad de definir y caracterizar el significado de su presencia, una ciudad del Clásico y su relación con Teotihuacán. Este trabajo presenta los principales datos obtenidos; se propone una cronología y se describen los elementos con influencia teotihuacana, entendida a través de la arquitectura, el arte monumental o portátil de origen, con derivación o inspiración teotihuacana, fuera del centro de México.
Historia y memoria de los huracanes y otros episodios hidrometeorológicos extremos en México: cinco siglos, del año 5 pedernal a Janet
Authors: García Acosta Virginia , Padilla Lozoya Raymundo
Published: March 2023

La presente obra es resultado de una serie de diversos esfuerzos para integrar un catálogo de los frecuentes huracanes y otros fenómenos hidrometeorológicos que han acontecido en México durante cinco siglos, contemplando desde la época prehispánica hasta el siglo XX. Los coordinadores de los textos del libro, integraron un amplio grupo de investigación, con múltiples resultados que son reportados en la parte medular del estudio. Esta publicación, además, está asociada a una base de datos, consultable en Internet, cuyo contenido aporta mayor detalle de lo relativo a gran cantidad de fenómenos meteorológicos y a las afectaciones que han ocurrido y que deben ser prevenidas en todo nuestro país.
La consumación de la Independencia. Nuevas interpretaciones (Homenaje a Carlos Herrejón)
Authors: Ibarra Ana Carolina , Ortiz Escamilla Juan , Tecuanhuey Alicia
Published: March 2023

Este libro reúne 19 ensayos de especialistas que se han planteado ofrecer una visión más rica y compleja del momento crucial que condujo a la separación definitiva de España. Sobre la base de investigaciones recientes, se analizan la trigarancia, los tratados de Córdoba, el discurso religioso y el pensamiento constitucional, en un contexto amplio americano, hispánico y atlántico, imprescindible para comprender una historia que se produce en diversos espacios. El libro hace, además, una aportación fundamental en el terreno de los estudios regionales que muestran las diversas dinámicas, la variedad de situaciones frente a los cambios que afectan a la América septentrional. Estudios sobre Puebla, Michoacán, Oaxaca, Yucatán o Zacatecas abren horizontes nuevos para comprender el proceso independentista y lo que vendría después.
Hacia una historia literaria integral: algunas categorías teóricas fundamentales y su aplicación en un esquema panorámico del proceso literario peruano
Authors: García-Bedoya Carlos
Published: March 2023

En el presente volumen, Carlos García-Bedoya evidencia las resonancias que hay entre categorías como “Polisistema”, “Campo literario” y “Totalidad contradictoria”, y con base en ello postula una sólida reflexión que se sitúa en el cruce entre las series histórico-social y literaria. Es así como las voces de Itamar Even-Zohar y de Pierre Bordieu reverberan con las de pensadores de Nuestra América, como Antônio Candido, Angel Rama y Antonio Cornejo Polar, y sirven para apuntalar un análisis del sistema literario peruano, caracterizado por su plural heterogeneidad y por su histórico proceso de transculturación.
Aproximaciones al hábitat
Authors: Salazar Martínez Bertha Lilia
Published: March 2023

En este documento se cuenta con la participación de profesores de los núcleos académicos del Doctorado en Arquitectura y Urbanismo, así como de la Maestría en Arquitectura de la Facultad de Arquitectura de la Universidad Veracruzana y otras instituciones, con la finalidad de buscar el mejoramiento del hábitat a través de una participación en conjunto. Se compone de tres apartados: “De la arquitectura objeto a la arquitectura proceso”, “Modo de vida rural y derechos” y “Reconociendo los fenómenos urbanos en curso”, que en su totalidad presentan investigaciones en la búsqueda del mejoramiento del hábitat. Con ello se cumple con el objetivo de difundir e incentivar las reflexiones en materia académica que permita que las propuestas actuales enfrenten los problemas del hábitat y su posible mejoramiento desde la visión de los autores, así como divulgar la pertinencia de las investigaciones en concordancia con las líneas de generación y aplicación del conocimiento “Hábitat, desarrollo y sociedad” y “Estudios y procesos urbanos”.