bluuebunny/crossref_metadata_2025 huggingface dataset:
TIRYAQ-I-AFAYEE (A POLYHERBAL FORMULATION) OF UNANI MEDICINE USED IN THE PREVENTION OF WABĀI AMRĀD (EPIDEMIC/ PANDEMIC DISEASES) – AN APPRAISAL
Authors: Ansari Athar Parvez , Arif Mohammad , Raheem Abdul , Iqbal Arsheed , Kausar Firdaus
Published: August 2021

BACKGROUND AND OBJECTIVE: Tiryaq-i-Afayee, a polyherbal formulation of Unani medicine used in the prevention and treatment of various wabāi amrād (epidemic/ pandemic diseases) since olden days. This review study has been carried out to explore the therapeutic efficacy of this formulation in the light of scientific studies.
MATERIALS & METHODS: A total of 74 literature comprising classical Unani texts from the period of 9th – 20th century AD, and published research articles in various reputed journals from 1999 – 2020 AD were reviewed regarding immunomodulatory, antiviral, antiinfluenza, antioxidant, antitussive, antimicrobial effects of Tiryaq-iAfayee, as a whole preparation and its individual ingredients.
RESULTS:Tiryaq-i-Afayee contains Sibr Zard (Aloe vera) (2 parts), Murr Makki (Commiphora myrrha) (1 part) and Zafran (Crocus sativus) (1 part). It is prepared in the form of pill, and 2 g is used in alternate day for prevention and management of epidemic diseases. All the three ingredients of this compound formulation belong to plants and individually used for various medicinal purposes.
DISCUSSION: A study revealed that Tiryaq-i-Afayee possesses significant immunomodulatory effect in a small group of immuno compromised persons. An ethanol extract of Aloe vera exhibited antiinfluenza effect against influenza A virus due to presence of aloe-emodine (anthraquinone glycoside). Certain studies have reported that Commiphora myrrha possesses significant antioxidant and antimicrobial effects against Staphylococcus aureus and Pseudomonas aeruginosa. Another study has revealed that Saffron extract exhibited promising antiviral activity due to presence of crocin and picrocrocin.
CONCLUSION: The aforementioned classical and modern conventional materials have given plentiful information regarding use of Tiryaq-i-Afayee in the prevention of epidemic/ pandemic diseases.
Examiners’ Comments on Masters’ Dissertations at the Islamic University in Uganda
Authors: Nimulola Maimuna
Published: August 2021

This study aimed at exploring the prevalence and nature of examiners’ comments on the appropriateness of draft M. Ed dissertations at Islamic University in Uganda. A total of 530 reports were stratified according to specialisations and examiners from which a sample of 300 reports were randomly selected. Content and thematic analyses were conducted on the reports whose findings were interpreted using Bourke and Holbrook’s (2013) indicators for assessment of Masters’ thesis quality. Findings reveal that under Contribution, ‘originality’ attracted few comments which tended to be neutral, while ‘substantive’ and ‘advancement of knowledge’ tended to be inappropriately done. The Literature Review ‘accuracy’ and ‘application’ categories were among the most highly commented on, with most of them tending to be inappropriately done, while relatively few comments were made on ‘literature coverage’. Under Approach/Methodology, ‘research design’ tended to be appropriately done while ‘sampling’, ‘validity’, and ‘reliability’ tended to be inappropriately done. In Analysis/Findings, ‘quantitative data presentation’ tended to be appropriately done, while ‘qualitative data analysis’ and ‘interpretation’ tended to be inappropriately done. Throughout the dissertation components, concerns on Presentation: ‘communicative competence’ and ‘expression’ were common. It is recommended that the university should engage Masters’ students more in seminars and workshops on research methods and scholarly writing.
A Predictive Study on Instructional Design Quality, Learner Satisfaction and Continuance Learning Intention with E-learning Courses: Data Screening and Preliminary Analysis
Authors: Kishabale Bashir , Hassan Sharifah
Published: August 2021

As E-learning initiatives are increasingly being deployed in educational and corporate training settings to revamp work-place productivity through life-long learning, concerns related to instructional design quality among stakeholders are equally growing. Thus, the overriding objective of the study was to carry out initial screening and preliminary analysis of the data related to the causal influence of instructional design quality on learner satisfaction and continuance learning intention. Based on the survey design, the quantitative data were collected from 837 students across ten CISCO Networking academies in Uganda. Descriptive statistics, multiple regression and factor analysis techniques were employed to address the purpose of the study. Primary attention was paid to the assumptions of response rate, missing data, outliers, data normality, multicollinearity, homoscedasticity and common method bias. The results of the initial screening and preliminary data analysis revealed non violation of prerequisite multivariate assumptions. The findings have provided empirical evidence on the psychometric study of which the instrument can be further used for future research. The steps taken for the analysis have provided a benchmark of audit trail in the methodology and statistical analysis for the replication of the study.
Scholarly Conceptions of the Nature of Academic Research in Universities: A Literature Review
Authors: Kaweesi Muhamadi
Published: August 2021

Conceptions of the nature of academic research in universities are blurred. Although higher education scholars concede that academic research within universities has been conceptualised in terms of basic and applied research, the conceptual debate with regard to what constitutes each type of research still lingers on. The purpose of this literature review is to highlight these conceptions by shedding light on how the nature of basic and applied research is understood in the extant literature.
Boards of Governors’ Roles and Management of Government Aided Secondary Schools in Kyenjojo District, Uganda
Authors: Wataba Hellen , Abiodun Nafiu
Published: August 2021

This study sought to establish the relationship between boards of governors’ (BOGs) roles and management of government aided secondary schools in Kyenjojo District. The objectives were to establish the relationship between BOGs’ planning role and management of government aided secondary schools, to establish the relationship between BOGs’ supervisory role and management of government aided secondary schools, to establish the relationship between BOGs’ control role and management of government aided secondary schools; and to determine the major predictor of management of government aided secondary schools out of the three aspects of BOGs’ roles. A correlational research design was used. A total of 90 respondents drawn from 108 BOGs and nine head teachers were selected as sample for the study using stratified random sampling and census inquiry respectively. The instruments used were questionnaire and interview guide. Quantitative data was analysed using Pearson product-moment correlation and regression, while thematic analysis was used on qualitative data. The study found a statistically moderate positive and significant relationship between BOGs’ planning role and management of government aided secondary schools (r=.626, p=.000); a statistically moderate positive and significant relationship between BOGs’ supervisory role and management of government aided secondary schools(r=.591, p=.000); and a statistically weak positive and significant relationship between BOGs’ control role and management of government aided secondary schools(r=.280, p=.015). All the three aspects of BOGs’ roles account for 38.4% of the influence on management of government aided secondary schools in Kyenjojo district (adjusted r2=0.384, p=.000). The researchers recommend that BOGs should be well trained in management of schools in order to be effective in their work. Head teachers should not be dictators but create a conducive climate for planning, supervision and control by the BOGs.
How I Survived Emotional Abuse: A Narrative Study
Authors: Yusof Siti
Published: August 2021

Children of divorce are not new to society yet their coping strategies are overlooked. Different abuse histories warrant a unique combination of coping strategies to deal with memories of past abuse. Coping has been put forward as an important element in understanding the long-term functioning of individuals with a history of emotionally abuse. The aim of this study was to investigate the challenges faced by a child of divorced parents, the coping strategies adopted by the child and how these coping strategies affected her level of perceived stress and life satisfaction. By using a narrative study, a female respondent, aged 13 who had been victimised through parental divorce was interviewed. Face-to-face interview was conducted by employing unstructured questions. Thematic analysis was implemented to analyse the data. Major themes found were; internal and external challenges, as well as positive and negative strategies. The results revealed that the child experienced mental health problems such as depression and loneliness during her childhood as a consequence of parental divorce which is perceived as a huge stressor or challenge in her life event. She engaged in both problem-focused and emotion-focused coping – using active emotion-focused coping other than avoidant focused coping – which led to boosting satisfaction in her life. This study contributes to school counsellors in helping school children, as well as for Muslim families with children coping with emotional abuse.
The Role of Education in the Development of Spirituality and Community Empowerment: Lessons from the Approach of Prophet Muhammad (SAW)
Authors: Miiro Farooq , Ssekamanya Siraje
Published: August 2021

From time immemorial, education has been used to empower and develop communities through equipping them with knowledge and putting that knowledge to practical use. Applied knowledge led to the development of great civilizations. In Islam, Prophet Muhammad (SAW) used education to change the course of history. Even after his death, the Islamic civilization spread far and wide covering most parts of the world. The main element in the educational approach of prophet (SAW) was the development of spirituality. Through this, he converted the harshest Bedouin Arabs into an admirable generation. Morality became the foundation of society with brotherhood as the basis of individual responsibility towards one another. In doing so, the Prophet (SAW) endeavoured to impart practical knowledge that his disciples translated into a true appreciation of meaning of life, thereby transforming themselves and creating a civil society that became a model for generations to come. This paper is intended to unpack the education strategies and processes that Prophet Muhammad (SAW) used to transform human life and how Muslim scholars practiced and conveyed them to generation after generation until when the British introduced Western education leading to the collapse of the Ottoman Empire.
A Correlation Analysis of School Plant Management and Curriculum Implementation in Bungokho County Secondary Schools, Mbale District, Uganda
Authors: Napokoli Prossy , Mwebesa Umar
Published: August 2021

The study examined the correlation between school plant management and curriculum implementation in government aided secondary schools in Bungokho County, Mbale District. It was guided by three hypotheses; Ho1 there is no statistically significant correlation between management of study materials and curriculum implementation; Ho2 there is no statistically significant correlation between management of physical infrastructure and curriculum implementation and Ho3 there is no statistically significant correlation between school location and curriculum implementation. Correlational research design was used as empirical road map with a sample size of 110 respondents who participated in the study. A piloted self-constructed questionnaire tool was used to collect data. It was then analyzed using inferential statistical tool of Pearson product-moment correlation coefficient and also by descriptive statistics of frequencies and percentages. The findings revealed that there was a strong positive correlation between school location management and curriculum implementation (r = .50, n =110, p<.05). The study found that there was a positive moderate correlation between study materials and curriculum implementation (r = .34, n = 110, p<.05). It was also discovered that there was a positive moderate correlation between physical infrastructure and curriculum implementation (r = .40, n =110, p<.05). The study recommended that; the school administrators should ensure that available school equipment is effectively used to facilitate content delivery for effective learning. There should be candid use of available physical infrastructure to enhance innovations and creativity among the teaching staff and students. The Boards of Governors managing secondary schools in Bungokho County and government stakeholders should ensure that any constructed secondary schools in the area should strategically and geographically be well located with ease of access.
Analysis and Research on the Requirements and Applicability of “Hualong-1” Commissioning Standards
Authors:   College of Standardization, The Open University of Guangdong, Jin Xiaoshi , Zhou Chuangbin ,   CGN Engineering Co., Ltd, China, 518124
Published: August 2021

Chinese nuclear power standards are parallel due to a variety of technical routes and different technology source countries, resulting in a situation of multiple standards parallel in the domestic nuclear power industry. Through the comparative analysis of nuclear power standards in the United States and France, domestic electric power industry and domestic conventional thermal power industry, this paper seeks for the combination point with domestic nuclear power commissioning standard system, and combs and analyzes the existing standard system. Through industry research and data collection and analysis, combined with the technical characteristics of “Hualong-1”, the requirements and applicability elements of the commissioning standard system are determined, the framework of the commissioning standard system is optimized and improved, and the corresponding standard acquisition, formulation and revision plan of the standard system is formed, so as to guide the construction of commissioning standardization.
Research on Optimal Strategy of Agricultural Products Marketing
Authors:   School of Economics and Management, Zhejiang Ocean University, Hu Linyan
Published: August 2021

With Agriculture occupies a high proportion of the national economy. National economic growth is mainly based on agricultural economic development. Optimizing agricultural product marketing strategies can greatly increase agricultural product sales, increase farmers’ income, help farmers find employment, and promote rural economic development. Therefore, studying how to optimize the marketing strategy of agricultural products has great value and practical significance. This article analyzes the main problems in the current agricultural product marketing through the research of the current situation of agricultural product marketing and the existing model, and then proposes the strategy of optimizing agricultural product marketing, and strives to accelerate the development of the rural economy, construct modern agriculture, and promote the implementation of the rural revitalization strategy. Finally, make a general recommendation on the effective measures to ensure the optimization strategy of the marketing model and how to implement it smoothly.
Innovation of Enterprise Economic Management Based on Knowledge Economy
Authors:   Faculty of Economics, Belarusian State University, Pan Jingchao
Published: August 2021

The development of economic globalization has put forward new requirements for the economic management of enterprises in China, and in order to occupy an advantage in the fierce international competition, enterprises must innovate enterprise economic management and establish their unique core competitiveness. To this end, this paper focuses on the two aspects of enterprise economic management and enterprise economic management innovation to study and explore.
Study on the Characteristics of Genealogy Contract Documents in Qing Dynasty
Authors:   School of International Education, North China University of Water Resources and Electric Power, Li Fengfan , Li Junjie ,   School of Marxism, Zhoukou Normal University
Published: August 2021

According to the data collected from the genealogical contract documents from the Qing Dynasty to 1949, the genealogical contract documents were first published in the Shunzhi period of the Qing Dynasty, and the contract documents clearly stated that the genealogical contract documents should be published in the Qianlong period. However, the surviving amount of genealogical deed documents is less than one thousandth of the existing genealogy. It is estimated that the surviving amount of genealogical deed documents is less than 5000. As for the type of genealogical contract document, it is roughly the same as the type of scattered contract document, mainly land sale contract document, and genealogical contract document is related to the interests of the clan. The main purpose of the contract in the genealogy is to protect the interests of the family property from loss, so as to maintain the permanent existence of the family property.
Research on Effective Teaching Strategies of Basketball General Course for Physical Education Majors in Colleges and Universities in China
Authors:   College of P.E. Science, Lingnan Normal University, Xin Songhe
Published: August 2021

Through the methods of literature review, expert interview and field investigation, this paper analyzes the effective teaching and promotion strategies of basketball general course for physical education major in Colleges and universities in China. It is believed that the main problems in the effective teaching of basketball general course of physical education major in China are cognitive bias in effective teaching, ignoring the effectiveness of teaching process, and dissimilation of effective teaching orientation In the problem, this paper puts forward the specific strategies to improve the effective teaching of general basketball course of physical education major in Colleges and universities, that is to correctly understand the effective teaching, pay attention to the effective teaching process, and establish the effective teaching goal orientation, so as to provide enlightenment for peer researchers to explore effective teaching together, and provide reference for peer workers to better understand effective teaching and improve effective teaching efficiency.
Application of Big Data Analysis in Medical and Health Institutions in Chengdu
Authors:   School of Economics and Management, Zhejiang Ocean University, Hao Yundong
Published: August 2021

With the development of social economy, information technology is developing constantly, and the whole society has entered the era of big data. The era of big data is mainly manifested in the large amount of data, various types, low value density, and high requirements for data processing speed and timeliness. In the era of big data, we should extract data in time and effectively, so as to promote the development of various industries. As an institutional industry that plays an important role in the cure of human health diseases, medical and health institutions have begun to gradually use big data to play an important role in the management of people's diagnosis and treatment. Taking medical and health institutions in Chengdu as an example, this paper explores how to use big data analysis in medical and health institutions, so as to improve the efficiency of medical treatment and medical quality.
Respecting and Protecting the Right of Minor Sexual Autonomy
Authors:   Law School, Fujian Normal University, Li Kang
Published: August 2021

The right of sexual autonomy is not only a natural problem, but also a humanistic problem. In the process of transformation from “biological man” to “rational man”, minors with certain rationality enjoy certain sexual autonomy. The basic concept of juvenile sexual autonomy includes respecting sexual freedom, safeguarding sexual dignity and promoting sexual autonomy. The sexual autonomy of minors faces two basic paths: tolerance and sternness; Has two functions: defense and attack. The state needs to fulfill the minimum obligation of respect and provide the space for the minor's voluntary autonomy. On this basis, the state should also fulfill the duty of protection to protect the space of minors' autonomy from being infringed.
Taking Responsibility First: A Survey of Social Responsibility of Small and Medium-sized Retail Enterprises in Beijing—Based on the Data of Four Districts
Authors:   University of International Business and Economics, No.10 Huixin East Street, Chaoyang District, Beijing, Zhao Haitao
Published: August 2021

Based on the logical framework of “Cognition and Motivation-Behavior-Performance”, this paper investigates the cognition and driving factors of managers of small and medium-sized enterprises to corporate social responsibility, and summarizes four behaviors of fulfilling social responsibility according to the Guide to Social Responsibility of Small and Medium-sized Enterprises in China, including employees, market, environment and community, and measures the corporate performance from three aspects: economy, society and environment. The results show that: (1) Social responsibility cognition has a significant positive effect on the fulfillment of social responsibility, and has a greater impact on the fulfillment of employees and market responsibilities; (2) The driving force of social responsibility has no significant effect; (3) Employees’ and environmental responsibilities have a positive impact on corporate performance, while market responsibilities and social responsibilities have no significant impact on corporate performance.
Book Review: Madness and Civilization: A History of Insanity in the Age of Reason
Authors:   Department of German, Nanjing Normal University, Wang Yue
Published: August 2021

This article briefly describes the main content and artistic value of the book Madness and Civilization: A History of Insanity in the Age of Reason, providing people with a new angle of reading and thinking.
The Educational Dilemma of Rural Left-behind Children and the Construction of Care System
Authors:   Ginling College, Nanjing Normal University, Tao Guoqing
Published: August 2021

Left-behind children in rural areas are a special group produced in the process of urbanization in my country. Left-behind children lack parental care in life and education. This article investigates whether left-behind children have an impact on the performance and cognitive abilities of left-behind children, and the magnitude of the influence. The results show that only left-behind children whose mothers go out and whose fathers are at home will have a significant decline in performance; the absence of parents will have a significant negative effect on the children’s cognitive ability. Based on the above education dilemmas for left-behind children, this article proposes to build a care system for left-behind children: on the one hand, the government, market and social forces should be integrated to ensure the effective connection of urban and rural education resources; on the other hand, through the national child welfare policy and local social welfare provision Organically combine to promote the development of left-behind children.
Challenges and Measures of the Financial Department of Chinese Universities under the New Personal Income Tax Laws
Authors:   Financial Department, Jianghan University, Zhang Huan
Published: August 2021

The withholding of personal income tax is an important work of financial department in colleges and universities. The new tax law implemented in 2019 has introduced a series of measures such as special additional deductions, which make the financial department of colleges and universities face new challenges. Starting from the positive and negative effects of the new personal tax law on the macro level, this paper further analyzes the positive and negative effects of the new personal tax law on the financial department of colleges and universities, and puts forward the overall and special measures to deal with the new personal tax law and provide corresponding countermeasures and suggestions for the financial department of colleges and universities.
Influence Analysis in Music: Artists and Genres
Authors:   College Information and Science, Northeastern University, Jia Naizheng , Zu Dian ,   College Information and Science, Northeastern University, Jia Baojun ,   Fushun Petrochemical Corporation, China
Published: August 2021

Music is an important part of human civilization, which is accompanied by the emergence and development of human civilization. While music is developing, different genres of music or musicians’ styles are all influencing each other. Therefore, it is significant to understand and measure the influence of music influencers and their followers in different genres of music with social development. Address to identify the influence network of American music, firstly, a PageRank model was proposed to calculate the music influence of every artist among the network. According to the results, we built the subnetworks to illustrate the influence of different sets. Then, we did research on distinguishing between genres, which utilized the random forest classifier. Furthermore, Gini impurity is used to demonstrate the feature's importance. Our result shows that Pop is the best influential genre, and acousticness is the most distinguishing feature.
The Research on the Product Humanization Model Based on the Evolution of Consumer Purchase Pat
Authors:   School of Economics and Management, Xi’an Technological University, Tao Na
Published: August 2021

Digital economy gives new connotation to business model. In the process of business model changing from vertical to horizontal, from exclusive to inclusive, and from individual to social, the central activity of enterprise marketing should be transferred to how to actively interact with consumers, so that consumers can more participate in the process of enterprise marketing value creation. This paper focuses on the model of consumers’ participation in marketing value creation. Firstly, this paper studies the basic model of consumer purchase path evolution, and proposes 5A +1D model based on the basic model. Then, based on the 5A+1D model, an important carrier for consumers to participate in the value creation of marketing is proposed: the product humanization model. Secondly, the paper analyzes the ideal migration mode of consumer purchase path under humanistic products: “W” model, which finally reaches the balance at both ends of 5A+1D model. Under the ecological background of open innovation, this paper extends the chain of consumers’ purchase path and realizes the co-creation of consumers and enterprises’ value, and designs a human-oriented product model based on the chain of consumers’ extended purchase path. The W model achieves the balance between the beginning and the end of the consumer purchase path model, which provides a theoretical basis for the intervention points of enterprises on the overall consumers’ purchase path.
Effects of Continuous Cropping of Dictyophora on Soil Physical and Chemical Properties, Microbial Biomass and Enzyme Activity
Authors:   Chongqing Forestry Science Research Institute, Tong Long , Li Hongyan ,   Chongqing Forestry Science Research Institute, Liu Xiaoming ,   Chongqing Forestry Science Research Institute, Li Bin ,   Chongqing Forestry Science Research Institute, Chen Lijie ,   Chongqing Forestry Science Research Institute, Chen Guilan ,   Chongqing Forestry Science Research Institute, Zeng Xiaoying ,   Chongqing Forestry Science Research Institute, Geng Yanghui ,   Chongqing Forestry Science Research Institute
Published: August 2021

The continuous obstacle of Dictyophora indusiata has become the one of the main factors affecting the healthy development of D. indusiata industry. In order to study the effects of continuous cropping of D. indusiata on the soil environment, four treatments were used in this study: no planted (CK), planted for 1 years (1Y), continuous cropping for 2 years (2Y) and continuous cropping for 3 years (3Y), to determined of the yield of D. indusiata, soil physical and chemical properties, microbial content and enzyme activity. The results showed that the yield and soil pH value decreased with the increase of continuous cropping years, and the contents of organic matter, total nitrogen, total phosphorus and total potassium, C/N and C/P also increased with the increase of continuous cropping years. Soil availability decreased with the increase of continuous cropping years, the content of alkaline nitrogen, available phosphorus and available potassium decreased by 12.25%, 28.91% and 24.86% at 3Y compared with 1Y, respectively. The biomass of bacteria, actinomycetes and fungi and the total amount of microorganism in soil increased at 1Y compared with CK, but with the increase of continuous cropping years, the biomass of bacteria and actinomycetes and the total amount of microorganism decreased significantly, while the biomass of fungi increased significantly; the continuous cropping of D. indusiata also decreased the value of bacteria/fungi in soil. The enzyme activities of the soil were higher than those of the unplanted plots, however, the activities of urease, catalase, peroxidase, sucrase, phosphatase and protease decreased with the increase of continuous cropping years. In a word, with the increase of continuous cropping, the acidity of rhizosphere soil increased, the availability of soil nutrients and the activity of soil enzymes decreased, the biomass of soil microorganisms, bacteria and actinomycetes decreased. However, the increase of fungal biomass led to the decline of soil texture.
O FEDERALISMO NO BRASIL E A PANDEMIA DA COVID-19
Authors: Lavor Leopoldina , Fontes Francisco Lucas de Lima , Menezes Monique
Published: August 2021

OBJETIVO: Analisar o federalismo e a pandemia da COVID-19 no Brasil, a partir da atuação dos(a) governadores(a) e prefeitos(as) das capitais, no enfrentamento à crise sanitária. MATERIAIS E MÉTODOS: Estudo exploratório com abordagem qualitativa. A técnica qualitativa empregada no estudo diz respeito à pesquisa documental, explorada mediante análise de discurso. RESULTADOS E DISCUSSÃO: Desde a Constituição de 1988, o Governo Federal sempre foi protagonista na coordenação das políticas públicas. A pandemia da COVID-19 tem mostrado, contudo, que o desenho do federalismo no Brasil permite que governadores(a) e prefeitos(a) possam assumir papel de liderança e coordenação. No caso da coordenação e cooperação entre governadores(a) e prefeitos(as) das capitais para o enfrentamento da pandemia, significativa parte das prefeituras buscou se articular com os governos estaduais, procurando a implementação de políticas conjuntas e coordenadas. CONSIDERAÇÕES FINAIS: O desenho do federalismo no Brasil propiciou que estados e municípios pudessem tomar medidas de enfrentamento à pandemia no lugar de ausência do governo federal. No entanto, uma coordenação do governo federal poderia apresentar parâmetros a serem seguidos, de acordo com os indicadores recomendados pelas autoridades de saúde.
Lymphogranulomatose vénérienne : A propos d'un cas observé dans le service Dermatologie,Bamako, Mali.
Authors: Sissoko M , Togola H , Diakité M , Coulibaly K , Dicko AA , Faye O
Published: August 2021

La lymphogranulomatose vénérienne (LGV) ou maladie de Nicolas et Favre fait partie des infections sexuellement transmissibles (IST) rares due au sérovar L1, L2 et L3 de Chlamydia trachomatis. Nous rapportons un premier cas de LGV dans le service de Dermatologie du Centre National d'appui à la lutte contre la maladie (CNAM) chez un sujet hétérosexuel présentant à l'examen clinique une hypertrophie éléphantiasique du scrotum et de la verge  associée à des fistules. Le diagnostic de LGV a été évoqué devant la clinique et confirmé par la sérologie chlamydiae. Une antibiothérapie a été instaurée (Doxycycline puis Azythromycine), a entrainé une régression progressive des symptômes en 4mois.
Zona planto-pédieux révélateur de l'infection à VIH
Authors: Keita L , Fofana Y , Sissoko M , Traore B , Diaby MG , Cisse L , Karabinta Y , Dicko AA , Faye O
Published: August 2021

Le zona est une dermatose virale qui peut intéresser n'importe quelle partie du corps. La plus part des personnes atteintes d'un zona ont entre 50 à 70 ans. Toutefois son apparition chez le sujet jeune doit fait rechercher une immunodépression à VIH. Nous rapportons un cas atypique de zona révélant l'infection à VIH chez une patiente de 25 ans présentant une éruption vésiculeuse, douloureuse reposant sur un fond érythémateux localisé sur la plante du pied gauche. Le diagnostic du zona a été évoqué grâce aux éléments cliniques et réconforté par le cytodiagnostic et l'histologie. Cette localisation atypique  nous a incités à demander une sérologie à VIH qui est revenue positive.
Choriorétinite toxoplasmique active de l'œil droit chez une adolescente à propos d'un cas
Authors: Diallo S
Published: August 2021

La choriorétinite toxoplasmique active constitue une affection rare chez les adolescents. Le diagnostic est principalement basé sur l'examen ophtalmologique et une réponse favorable au traitement. Nous rapportons le cas d'une adolescente de 18 ans reçue pour une vision floue avec douleur oculaire. L'examen du segment antérieur est sans particularité. Le fond d'œil au niveau de  l'œil droit retrouve un foyer  de choriorétinite toxoplasmique active. L'examen ophtalmologique de l'œil gauche est sans particularité. Le bilan para clinique effectué chez la patiente montre un test de REMINGTON positif à 2 reprises distants de 3 semaines.  L'évolution clinique après l'instauration du traitement était favorable avec une cicatrisation du foyer actif en un mois.
Sphingomonas paucimobilis: Un phénotype de multi-résistance inhabituel chez un probable pathogène émergent
Authors: Makanera A , Condé M , Diallo MA , Condé M , Camara D
Published: August 2021

Introduction: La multi-résistance aux antibiotiques devient un phénomène inquiétant chez des bactéries pathogènes et pathogènes émergentes. Objectif: L'objectif de ce travail était de décrire un phénotype de multi-résistance aux antibiotiques chez une souche de Sphingomonas paucimobilis. Patiente et méthodes: Une patiente de 55 ans a été reçue le 29 Novembre 2017 à l'Hôpital de l'Amitié Sino-Guinéenne (Kipé/Conakry) pour des examens cytobactériologiques  des urines. L'identification bactérienne et l'antibiogramme ont été faites à l'automate Vitek2 compact 15 (Biomérieux, Marcy l'Etoile, France). Résultats : L'identification bactérienne a révélé la présence de Sphingomonas paucimobilis. Les antibiogrammes réalisés avec les cartes AST-N 233 et AST-XN05 ont montré une résistance à tous les antibiotiques testés avec des CMI élevées, à l'exception des tétracyclines et du chloramphénicol. Conclusion : Nos résultats montrent que la souche de Sphingomonas paucimobilis étudiée pourrait être considérée comme une bactérie pathogène émergente présentant un phénotype de multi-résistance à différentes familles d'antibiotiques.
Connaissance, Attitudes et pratiques des élèves sur l'hygiène alimentaire et l'alimentation de la rue
Authors: Soumahoro SI , Coulibaly M , Kouassi DP , Irika O , Goua BI , Ouaga JM , Angbo-Effi O
Published: August 2021

Introduction : Dans les pays en développement, les risques de contamination des aliments sont à la fois présents à domicile que chez les vendeurs mais avec un risque de contamination plus élevé des aliments de la rue. Au regard des risques encourus par la transmission de maladies par les aliments, nous avons mené cette étude auprès des élèves de Bouaké afin d'apprécier leurs connaissances, attitudes et pratiques vis-à-vis de l'hygiène des aliments vendus dans les rues dans le but d'améliorer les comportements en hygiène alimentaire des élèves.

Méthode : Nous avons mené une étude transversale à visée descriptive dans quatre établissements secondaires, dont deux publics et deux privés, de la ville de Bouaké. Nous avons interviewé 448 élèves grâce à un questionnaire. Le logiciel SPSS 17.0 a été utilisé pour la saisie et l'analyse des données recueillies.

Résultats : Les élèves interrogés avaient un âge médian de 16 ±5,2 ans, étaient majoritairement de sexe masculin (60,0%) et percevaient de l'argent de poche dans 92,2% des cas. Nos enquêtés affirmaient qu'il fallait se laver les mains avec de l'eau et du savon (99,1%) et se lavaient systématiquement les mains avant chaque repas (94,9%). Ils ne faisaient pas confiance aux aliments vendus à l'école ou dans la rue (64, 1%) et certains élèves interrogés disaient être tombés malades après consommation d'aliments vendus dans la rue (53,6%).

Conclusion : Le respect des pratiques d'hygiène alimentaire est le garant de la prévention de nombreuses maladies infectieuses. Des dispositions en rapport avec un meilleur contrôle de l'alimentation de rue devraient être prises pour minimiser le risque de survenue des maladies infectieuses liées à l'Alimentation de la rue
Recherche de la staphylocoagulase libre à partir du plasma d'animaux tropicaux : influence du type d'anticoagulant, de la température et de la durée de conservation
Authors: Dougnon V , Yehouenou B , Dansi Soclo F , Houefone A , Zehounkpe F , Amadou A , . al Et
Published: August 2021

L'identification biochimique de Staphylococcus aureus nécessite la recherche de la staphylocoagulase libre, réalisée grâce au plasma lyophilisé de lapin. Cette étude vise à promouvoir l'utilisation de plasma frais d'animaux tropicaux et déterminer l'influence des anticoagulants, de la température et de la durée de conservation de ces plasmas dans la révélation de la staphylocoagulase libre.Cinq (5) échantillons de sang de rats wistar, 3 de porc, 10 de poulets et 10 de lapins ont été recueillis sur anticoagulants. Après caractérisation biochimique d'une souche de référence de S. aureus ATCC 25923, la recherche de la staphylocoagulase libre a été faite à partir des plasmas d'animaux tropicaux conformément aux critères bactériologiques classiques. Des résultats obtenus, seuls les échantillons de plasma de lapins et de porcs ont permis la révélation de la staphylocoagulase libre. De tous les anticoagulants testés, l'EDTA et Citrate de sodium ont été les plus efficaces. Une part des plasmas de lapins recueillis sur EDTA a été conservée au réfrigérateur et l'autre part à température ambiante durant sept jours. La recherche de la staphylocoagulase a été faite tous les jours de conservation à partir des plasmas. Il découle de cette conservation que la température n'a pas d'influence majeure sur les échantillons de plasma sauf que leur conservation à température ambiante ralentit l'obtention des résultats. Il est donc préférable pour l'obtention de résultats dans un temps relativement court et pour éviter les risques de contamination des plasmas, de les conserver au réfrigérateur entre 2° et 8°C pendant un maximum de 6 jours.
Non-compliance aux messages de prévention de la maladie à virus Ebola en Côte d'ivoire dans un contexte de menace à l'épidémie
Authors: Soumahoro SI , Kouassi DP , Coulibaly M , Kouamé AD , Irika O , Ouaga JM , .al Et
Published: August 2021

Introduction : La pandémie ouest-africaine de 2013-2016 de la maladie à virus Ebola a provoqué une psychose mondiale. Le gouvernement ivoirien, fort de la proximité géographique de la Côte d'Ivoire avec les pays touchés, a instauré plusieurs mesures. Il s'agissait entres autres d'un vaste programme d'éducation sanitaire de la population constitué de 20 mesures à observer par les populations. Nous avons mené cette étude pour apprécier les raisons de non compliance des populations aux mesures de prévention instituées et les déterminants sociodémographiques en rapport.

Méthode: Nous avons mené une étude transversale à visée descriptive  et analytique pendant 01 mois, du 11 mars 2017 au 10 avril 2017, dans les ménages de la ville de Bouaké. Nous avons interviewé 405 personnes grâce à un questionnaire. Les logiciels Epi Info 2000 et SPSS 17.0 ont été utilisés pour la  saisie et l'analyse statistique des données recueillies.

Résultats : Les adultes avaient une moyenne d'âge de 36,34±1,60 ans et les enfants de  13,1 4± 11,27 ans. Certains enfants étaient non-scolarisés (4,3%) et les adultes avaient un niveau d'instruction supérieur dans 31,3% des cas. Les mesures les moins observées étaient les mesures 3 (42,5%), 1 (8,6%), 5 (5,7%) et 7 (5,7%). Les raisons les plus évoquées étaient la courtoisie (27,4%), l'habitude (21,0%), le respect de la coutume (13,1%) et l'oubli (11,6%). Pour la mesure 1, toutes les caractéristiques sociodémographiques y étaient statistiquement associés (p<0,000).

Conclusion :Il importe de cerner tous les contours des messages de sensibilisation et de prévention afin de s'assurer d'une totale adhésion des populations.
Antibioprophylaxie pour chirurgie de médecine humanitaire en zone de conflit au Mali
Authors: Sidibé A , Diani N , Dicko H , Beye SA , Keita M , Diarra D , Coulibaly CO
Published: August 2021

Objectif : Identifier les antibiotiques utilisés et évaluer notre pratique en médecine humanitaire. Patients et Méthode : Etude prospective  de 30 jours. La saisie et l'analyse des données ont été faites par Windows 8, Epi info 3.5.3 fr et le khi² pour le  test statistique. Résultats : Soixante-trois (63) patients  répondaient aux critères. L'âge moyen était de 33,3 ±  18, 5 ans. Les femmes rurales prédominaient. Les urgences représentaient  65,1% des cas.  L'indication de l'antibioprophylaxie était Gynéco-obstétricale dans  63, 5%  suivie de la chirurgie  viscérale dans 20,6%, de l'urologie dans 11,1%  et de la traumatologie dans 4,8%. Les patients  étaient ASA I dans  69,8%. La classe d'Altémeier était II dans 81%. Une antibioprophylaxie a été faite dans 88,9%.  Les β lactamines en monothérapie ont été les plus utilisées dans 84,1% suivies de  l'association β lactamine-imidazole dans 9,5%, de l'association β lactamine-aminoside dans 1,6% et les quinolones dans 1,6%. Le délai entre l'administration de l'antibiotique et l'induction anesthésique était de : 6 ±  2,4 minutes. L'antibiotique a été administré  entre 25 et 40  minutes avant l'incision chirurgicale. Une complication infectieuse a été observée dans  11, 1%. L'évolution était favorable dans 98,4%.Conclusion :   Même en situation de crise sanitaire, l'utilisation de l'antibiotique  au bloc opératoire doit  répondre à des critères  dont l'écologie microbienne et le site opératoire sont déterminants.
Update on Treatment and Prevention of Chronic Antibody Mediated Rejection in Renal Transplant Recipients
Authors: Shafi Salman Tahir
Published: August 2021

Chronic antibody mediated rejection (AMR) is a major cause of allograft failure1,2. Chronic AMR clinically presents with proteinuria and gradual decline in renal function. The underlying mechanisms of AMR include both antibody mediated complement-dependent cytotoxicity, complement-independent cellular cytotoxicity and other mechanisms. The purpose of this review is to appraise recent literature on diagnosis, treatment and prevention of chronic AMR.
Fluid Volume Status Assessment by Lung Ultrasonography in Patients with Kidney Disease.
Authors: Saigal Navid
Published: August 2021

Point-of-care ultrasound (POCUS) has become firmly established in acute and critical care settings and has now emerged as an important tool in the assessment of the Extra Vascular Lung Water (EVLW). Lung ultrasound (LUS) can be performed quickly and easily in critically ill patients. It has a higher diagnostic accuracy than physical examination and chest radiography combined. It enhances safety by avoiding ionizing radiation and the need for potentially dangerous transfers within the hospital. LUS can also be used to guide fluid management.
Uremic Cardiomyopathy
Authors: Umer Amna , Khan Muhammad Azhar Waheed , Javed Maryam , Khan Azhar Ali
Published: August 2021

Chronic Kidney Disease (CKD) affects approximately 10% of the general population. CKD itself is a risk factor for cardiovascular mortality and morbidity. Large epidemiological studies have clearly established a clear relationship between severity of CKD and cardiovascular event rates. Sudden cardiac death accounts for approximately 40% mortality in dialysis patients and it is usually secondary to an underlying cardiomyopathy, with left ventricular hypertrophy mostly evident on echocardiography. Several risk factors play an important role in pathogenesis of uremic cardiomyopathy including vitamin D deficiency, secondary hyperparathyroidism, phosphate retention, increased FGF23 and decreased Klotho levels. The mortality due to cardiovascular events in early stage CKD is relatively higher in comparison to progression to ESRD, so early diagnosis and treatment with dialysis should be focused.
Dexmedetomidine Related Polyuria and Hypernatremia in Intensive Care Unit.
Authors: Dilawar Mubashar , Riaz Muhammad Mohsin , Sabir Omer , Basit Muhammad Bilal
Published: August 2021

Dexmedetomidine is commonly used sedative nowadays. It’s being used as an anesthetic for surgical procedures and frequently being used in ICU Settings for sedation, and analgesia. Dexmedetomidine is a highly selective, alpha-2 agonist that also blocks arginine-vasopressin release. Dexmedetomidine is suspected to cause diabetes insipidus leading to polyuria and hypernatremia. We report a case of Diabetes Insipidus associated with use of dexmedetomidine.
CUT OFF VALUE OF PROCALCITONIN IN END STAGE RENAL DISEASE PATIENTS WITHOUT INFECTION
Authors: Asif Naila , Shamim Samina , Khanzada Shafqat Waqar , Rizwan Muhammad
Published: August 2021

OBJECTIVE:

To determine cut off value of procalciton (PCT) in aseptic end stage renal disease patients undergoing haemodialysis.

BACKGROUND:

Haemodialysisis considered as a proinflammatory state and therefore associated with release of inflammatory cytokines and acute phase reactant proteins. The conventional laboratory markers (C-reactive protein, erythrocyte sedimentation rate) are efficient tools for the diagnosis of infection in patients with normal kidney functions. However they can be nonspecifically elevated in patients on haemodialysis and only reflect inflammatory response not associated with infection. PCT is considered a very important biomarker in differentiating infections from inflammation. The study was undertaken to evaluate normal serum levels of PCT in patients undergoing HD.PATIENTS AND METHOD: The study included 82 end-stage renal failure patients without evidence of systemic or localized infection undergoing maintenance haemodialysis.

RESULTS: In our study, the PCT concentrations showed a mean of .622ng/ml in patients on maintenance hemodialysis without signs of infection.

CONCLUSION:The study suggests that serum PCT at a cutoff value of .62ng/ml should be considered normal in aseptic haemodialysis patients.

KEYWORDS:

Procalcitonin, haemodialysis, sepsis