bluuebunny/crossref_metadata_2025 huggingface dataset:
Movemento feminista e educación en Galiza: 1970-1990
Authors: Mariño Costales Mariam
Published: September 2020

Co obxectivo de contribuír á reflexión sobre os espazos e ámbitos de relacións sociais vinculados coa educación e as lóxicas destinadas á transformación de modelos e contidos relacionados coa aprendizaxe, neste artigo tómase como eixo de análise a rede de relacións xerada pola actividade de organizacións feministas en Galiza desde 1970 ata 1990. Segundo a hipótese manexada aquí, na citada rede articúlanse críticas, propostas e estratexias de loita que insisten de xeito particular na necesidade de repensar e mudar os procesos de marxinalización, discriminación e inxustiza social inscritos nas relacións establecidas de xeito dominante entre sexos, xéneros e sexualidades. Ditas propostas non restrinxen a educación ás fronteiras dos espazos académicos escolares, pois actívanse coa intención de ser aplicadas a nivel externo e interno; no persoal, nos propios agrupamentos e en todos os espazos e ámbitos de relacións sociais.
Oralidade e escrita na cultura popular
Authors: Díaz Balado Alicia
Published: September 2020

O avance na consolidación do modelo económico capitalista esixía racionalizar a medida do tempo nos diferentes territorios europeos, tanto para o fomento da productividade económica, como para o ‘disciplinamento’ social. Así, o calendario, que fora unha mediación característica, pero tamén variable, da sociedade tradicional, foise convertendo durante a Modernidade tardía e a Contemporaneidade nunha publicación impresa crecentemente popular, paulatinamente normalizada como xénero impreso. Como obxecto de consumo cultural, o calendario ou almanaque incorporou novidades científicas nas súas páxinas publicitarias, conxuntamente cos contidos máis tradicionais e desenvolveu un rol formativo en contextos informais de educación.
S. Braster, F. Simon & I. Grosvenor (2013). A History of Popular Education
Authors: Bolaño Amigo Uxía
Published: September 2020

Recensión de libro: S. Braster, F. Simon & I. Grosvenor (2013). A History of Popular Education.
Elena Sánchez de Madariaga et al. (ed.) (2012). Las maestras de la República
Authors: Bolaño Amigo Uxía
Published: September 2020

Recensión de libro: Elena Sánchez de Madariaga et al. (ed.) (2012). Las maestras de la República.
A study on obstetric patients with corona virus infection requiring critical care
Authors: Preet Adarsh , Palve Tushar
Published: September 2020

Background: Coronavirus cause respiratory tract infection that can range from mild to lethal like cold, fever, cough, shortness of breath, fatigue, chills, body aches, headache, sore throat, loss of smell or taste, nausea, diarrhoea, pneumonia, respiratory failure, septic shock and death. The purpose of this study was to describe the clinical manifestations of obstetric patients with COVID-19 infection requiring critical care, their 02 requirements, complications, co-morbidities associated and mortality related to it.Methods: A study was conducted in the Department of Obstetrics and Gynecology, Cama and Albless hospital, Mumbai including 31 patients with SARS CoV-2 infection requiring critical care. Necessary information such as their detailed clinical, and obstetric history, clinical examination, investigations was noted.Results: In our study, the most common symptoms were shortness of breath, followed by fever. PIH was the most common co morbidity associated and pneumonia as most common complication. Anemia, thrombocytopenia and NLR>4 were found more common in intensive care unit (ICU) admitted patients as compared to non-ICU admitted patients. 77.4% of patients had abnormal chest X-ray with 25.8% requiring mechanical ventilation.Conclusions: COVID 19 infection is affecting pregnant women resulting in mild to lethal disease. Most of pregnant women are asymptomatic or have mild disease but some of them require critical care. These women should be monitored carefully to prevent maternal morbidity and mortality.
Utility of Rinne’s tuning fork test for quantitative assessment of conductive hearing loss
Authors: Senniappan Shivakumar , Chendigi Rohith
Published: September 2020

Background: The Rinne tuning fork test is used routinely in clinical ENT examination. It is used to assess the person’s hearing acuity. Ideally, 3 tuning forks are used 256, 512 and 1024 Hz. Rinne tuning fork tests can be used to diagnose conductive hearing loss. Aim of our study an attempt is made to find the utility of three different tuning forks (256,512,1024 Hz) for quantification of conductive hearing loss and their accuracy.

Methods: A retrospective study with a sample size of 300 was undertaken over 12 months from April 2018 to March 2019 at the out-patient department of ENT of VMKV medical college and hospital, Salem. Patients of both sexes and aged above 10 yrs presenting with conductive hearing loss due to varied etiology were subjected to complete ENT examination including Rinne test with three different tuning forks (256, 512, 1024 Hz).

Results: The results of all the tuning forks (256, 512, 1024 Hz) shows that 29 patients were Rinne’s positive to all tuning forks had the air-bone gap range of 15 dB to 19 dB with a mean air-bone gap of 17.63 dB. 83 patients were negative to 256 Hz tuning fork but positive to 512 and 1024 Hz tuning forks had the air-bone gap range of 20 to 29 dB with a mean air-bone gap of 25.46 dB.

Conclusions: We conclude that Rinne’s tuning fork test can be used to quantify the degree of conductive hearing loss into mild (20-30 dB), moderate (30-45 dB), and severe (45-60 dB).
Elements of Open Education: An Invitation to Future Research
Authors: Zawacki-Richter Olaf , Conrad Dianne , Bozkurt Aras , Aydin Cengiz Hakan , Bedenlier Svenja , Jung Insung , Stöter Joachim , Veletsianos George , Blaschke Lisa Marie , Bond Melissa , Broens Andrea , Bruhn Elisa , Dolch Carina , Kalz Marco , Kondakci Yasar , Marin Victoria , Mayrberger Kerstin , Müskens Wolfgang , Naidu Som , Qayyum Adnan , Roberts Jennifer , Sangrà Albert , Loglo Frank Senyo , Slagter van Tryon Patricia J. , Xiao Junhong
Published: September 2020

This paper explores elements of open education within the context of higher education. After an introduction to the origins of open education and its theoretical foundations, the topics of open and distance learning, international education issues in open education, open educational practices and scholarship, open educational resources, MOOCs, prior learning accreditation and recognition, and learner characteristics are considered, following the framework of macro, meso, and micro levels of research in open and distance learning. Implications for future research at the macro, meso, and micro levels are then provided.
Does Delivery Model Matter? The Influence of Course Delivery Model on Teacher Candidates’ Self-Efficacy Beliefs Towards Inclusive Practices
Authors: Smothers Moriah , Colson Tori , Keown Stacey
Published: September 2020

A causal-comparative research design was used to examine the influence of course delivery (face-to-face flipped or asynchronous online) on participants’ self-efficacy beliefs toward teaching in an inclusive classroom. The following research questions were used to guide the study: (a) Is there a relationship between completing an introduction of exceptionalities course and participants’ self-efficacy toward teaching an inclusive classroom? (b) Is there a relationship between completing an introduction of exceptionalities course in an asynchronous online or face-to-face flipped format on participants’ self-efficacy beliefs toward teaching in an inclusive classroom? The purpose of this study was to explore if there is a relationship between self-efficacy belief development and course delivery models. The results indicated a significant difference in self-efficacy beliefs towards teaching in an inclusive classroom after completing an introduction of exceptionalities course. However, there was no significant difference in the participants’ efficacy based on the course delivery model (face-to-face flipped or asynchronous online). Implications and suggestions for future research are discussed.
Learners’ Discussion Patterns, Perceptions, and Preferences in a Chinese Massive Open Online Course (MOOC)
Authors: Ouyang Fan , Li Xu , Sun Dan , Jiao Pengcheng , Yao Jiajia
Published: September 2020

The development of massive open online courses (MOOCs) has proceeded through three generations, and in all three, online discussions have been considered a critical component. Although discussions in MOOCs have the potential to promote learning, instructors have faced challenges facilitating learners’ knowledge inquiry, construction, and management through social interaction. In addition, understanding various aspects of learning calls for more mixed-method studies to provide both quantitative, generalized analysis and qualitative, detailed descriptions of learning. This study fills these practice and research gaps. We designed a Chinese MOOC with the support of a pedagogical strategy, a learning analytic tool, and a social learning environment in order to foster learner engagement in discussions. Mixed methods were used to explore learners’ discussion patterns, perceptions, and preferences. Results indicated that learners demonstrated varied patterns, perceptions, and preferences, which implies a complex learning process due to the interplay of multiple factors. Based on the results, this research provided theoretical, pedagogical, and analytical implications for MOOC design, practice, and research.
Revisiting Textbook Adaption Through Open Educational Resources: An Inquiry into Students’ Emotions
Authors: Zhang Xiaodong
Published: September 2020

This qualitative study explored the emotional trajectories students experienced when faced with open educational resources (OER) that expanded the learning available from a required textbook. Data included students’ reflections, group discussions, and interviews, along with field notes which were collected in a classroom at a Chinese university in one semester. The study showed that students’ initial positive emotions arose from their understanding of their own learning needs. Their positive emotions toward the conjugated use of OER and a textbook fluctuated over the semester but were gradually enhanced through their involvement in classroom practices (e.g., knowledge building and teacher mediation). Through the process, students’ positive and negative emotions respectively facilitated and hampered their learning practices; however, negative emotions were not always detrimental—they also facilitated students’ learning. Students’ emotions gradually stabilized in the direction of being positive, especially in tandem with (a) achievement of sufficient knowledge gained through OER-based textbook use and teacher-mediated learning, and (b) their augmented confidence in proficiently using the new knowledge to navigate their practices.
Sofrimento em Doentes em Fim de Vida na Era COVID-19
Authors: Vasconcelos Adriana , Azevedo Marta
Published: September 2020

N/a.
Intracranial Hemorrhage in Patients With Hemophilia A
Authors: Budi Nugroho Setia , Airlangga Prananda Surya , Semedi Bambang Pujo
Published: September 2020

Introduction: Intracranial hemorrhage in inherited bleeding disorders is a medical emergency. The location of bleeding in most children is subdural and the most common cause is hemophilia. Although intracranial bleeding that occurs in people with hemophilia ranges from less than 5% of events, it is a life-threatening medical emergency so appropriate treatment is needed. Case Report: A boy patient 11 years old, 20kg weights have a seizure at home and followed by a decrease in consciousness. It was founded abnormalities in the form of anemia, prolonged FH (PPT 4x and APTT 4x), and hypocalcemia. The patient then was given main therapy; FVIII 100 IU/dL according to the FVIII target level calculated. The therapy continued with 500IU/12 hours according to the daily target of FVIII 50IU/dL. Discussion: The patient’s condition was getting better day by day. The patient’s consciousness started to improve after 14 days of postoperative. One month after that, the patient received koate treatment as the episodic handler. Diagnosing the exact cause in patients who have intracranial hemorrhage provides appropriate management so that the patients could be helped. Conclusion: Good collaboration between anesthesiologists, neurosurgeons, and pediatrics will increase the probability of successful management of critical bleeding without major sequelae.
Batasan, Wewenang dan Keterlibatan KPPU Dalam Kasus Persekongkolan Tender Menurut Hukum Persaingan Usaha
Authors: Maheswari Alya Anindita
Published: September 2020

Dewasa ini perekonomian dunia semakin maju, banyak negara berkembang yang hingga saat ini berusaha meningkatkan taraf perkenomian negara, tak terkecuali Indonesia. Semakin maju perekonomian, semakin banyak pula peluang dan pesaing dalam meluaskan suatu usaha. Di Indonesia permasalahan yang paling mendasar dalam hal perekonomian saat ini salah satunya adalah mengenai persekongkolan tender. KPPU sebagai lembaga pengawas yang mengawasi arus persaingan usaha di Indonesia, berwenang untuk memberikan sanksi dan tindakan administratif kepada pelaku usaha yang terbukti melakukan persaingan usaha tidak sehat, salah satunya adalah persekongkolan. Persekongkolan ini termasuk dalam klasifikasi tindakan yang dilarang oleh Undang-Undang Nomor 5 tahun 1999 karena dapat merugikan keuangan negara. Undang-Undang Nomor 5 tahun 1999 mengatur tindakan persekongkolan dapat dijatuhi sanksi administratif dan sanksi pidana. Peraturan dalam Undang-Undang Nomor 5 tahun 1999 adalah wewenang khusus yang dimiliki oleh KPPU, termasuk mengenai sanksi pidana. Tujuan penulisan ini adalah untuk mengkaji sejauh mana batasan dan wewenang KPPU dalam penerapan sanksi pidana terhadap kasus persekongkolan tender yang berimplikasi tindak pidana.
Pekerja Rumah Tangga Sebagai Korban Kekerasan Dalam Rumah Tangga
Authors: Daud Erita Rosa Larasati
Published: September 2020

Artikel yang berjudul “Pekerja Rumah Tangga Sebagai Korban Kekerasan Dalam Rumah Tangga” berlandaskan pada penelitian yuridis normatif dengan pendekatan perundang–undangan dan pendekatan konseptual. Peraturan perundang-undangan yang mengatur mengenai “Pekerja Rumah Tangga Sebagai Korban Kekerasan Dalam Rumah Tangga” ada di dalam Undang-Undang Nomor 23 Tahun 2004 mengenai Penghapusan Kekerasan Dalam Rumah Tangga dan Peraturan Menteri Ketenagakerjaan Nomor 2 Tahun 2015 Tentang Perlindungan Pekerja Rumah Tangga. Penelitian ini bertujuan untuk mengetahui dan menganalisis perlindungan hukum bagi Pekerja Rumah Tangga yang menjadi korban KDRT. Salah satu penyelesaian kasus tindak pidana KDRT yaitu terdapat upaya non litigasi berupa mediasi penal dimana kedua pihak dipertemukan dengan ditengahi oleh Pihak Kepolisian untuk menyelesaikan kasus KDRT. Untuk upaya ini belum diatur dalam Undang–Undang Nomor 23 Tahun 2004, sehingga mediasi penal tidak memiliki dasar peraturan perundang–undangan yang mengatur dengan jelas prosedur dan tata caranya serta hanya berdasar dari kewenangan diskresi dari Undang-Undang Kepolisian. Sehingga untuk upaya mediasi penal yang belum diatur secara tegas dalam UU PKDRT, Penulis memberi saran untuk revisi UU PKDRT, pembuat undang-undang memasukkan mediasi penal sebagai salah satu alternatif penyelesaian masalah KDRT agar terdapat dasar hukum yang jelas.
Tindak Pidana dan Pertanggungjawaban Pidana Pelaku Penyalahgunaan Senjata Tajam
Authors: Rosady Rakyu Swanabumi Rahmantara
Published: September 2020

Kepemilikan dan peredaran senjata tajam di Indonesia masih sangat minim pengaturan. penelitan ini bertujuan mengetahui terkait pengaturan kepemilikan dan peredaran senjata tajam itu sendiri dan pengaturan mengenai penyalahgunaan senjata tajam. pengaturan senjata tajam diatur dalam Undang-Undang No. 12/Drt/1951 mengatur 2 hal pokok antara lain ialah Pasal 1 Undang-Undang No. 12/Drt/1951 mengatur mengenai senjata api dan secara spesifik senjata tajam diatur dalam Pasal 2 Undang-Undang No. 12/Drt/1951. Pasal 2 ayat (1) mengatur mengenai tindak-tindakan yang tidak iperbolehkan mengenai senjata tajam yang ilegsl dan juga yang disebut senjata tajam tersebut ialah senjata pemukul, senjata penikam dan senjata penusuk dan pada Pasal 2 ayat (2) mengatur mengenai klasifikasi alasan seseorang dapat memiliki senjata tajam. Dalam prakteknya pengimplementasian Pasal 2 Undang-undang No. 12/Drt/1951 masih sangat kurang karena masih banyak di Indonesia orang ditangkap dengan alasan memiliki senjata tajam yang jelas senjata tajam tersebut digunakan seusai dengan Undang-Undang dan juga terkait pengawasan mengenai senjata tajam masih sangat minim karena masih banyak di temukan senjata tajam yang jelas jelas tidak di perbolehkan beredar tetapi senjata tajam tersebut malah dijual dengan sangat bebas.
Effect of Power-Assisted Functional Electrical Stimulation (PAFES) and Occupational Exercise on Motor Unit Activity of Extensor Digitorum Communis and Hand Dexterity in Post-stroke Patient
Authors: Roni Yusuf , Wulan Sri Mardjiati Mei , Pawana I Putu Alit
Published: September 2020

Background: Weakness of upper extremity can affect the ability to perform daily activities in post-stroke patients. Power-Assisted Functional Electrical Stimulation (PAFES) may give motor reeducation and sensory feedback to improve motor recovery through neuroplasticity.Aim: To evaluate the effect of PAFES and occupational exercise on post-stroke patient hand dexterity and motor unit activity of extensor digitorum communis muscle.Material and methods: Twenty post-stroke patients enrolled in the study were divided intervention group whom received PAFES and occupational exercise, and control group whom received occupational exercise only. Each group underwent 30 minutes per session of treatment, 5 times a week, for 3 weeks. The Root Mean Square (RMS) for measuring motor unit activity of extensor digitorum communis muscle; Box and Block Test (BBT) and Nine Hole Peg Test (NHPT) for measuring hand dexterity were evaluated before and after intervention.Result: There were significant improvements of RMS (p<0.001), BBT (p<0.001) and NHPT (p=0.002) in intervention group after receiving PAFES and occupational exercise. The improvement of BBT in intervention group was significant compared with control group (p=0.028), however, no significant improvement of NHPT was found between groups.Conclusion: PAFES and occupational exercise could improve motor unit activity of the extensor digitorum communis muscle and hand dexterity in post-stroke patient.
Real-Time Plant Health Assessment via implementing Cloud-Based Scalable Transfer Learning on AWS DeepLens
Authors: Khan Asim , Nawaz Umair , Ulhaq Anwaar , Robinson Randall W.
Published: September 2020

In the Agriculture sector, control of plant leaf diseases is crucial as it influences the quality and production of plant species with an impact on the economy of any country. Therefore, automated identification and classification of plant leaf disease at an early stage is essential to reduce economic loss and to conserve the specific species. Previously, to detect and classify plant leaf disease, various Machine Learning models have been proposed; however, they lack usability due to hardware incompatibility, limited scalability and inefficiency in practical usage. Our proposed DeepLens Classification and Detection Model (DCDM) approach deal with such limitations by introducing automated detection and classification of the leaf diseases in fruits (apple, grapes, peach and strawberry) and vegetables (potato and tomato) via scalable transfer learning on A.W.S. SageMaker and importing it on A.W.S. DeepLens for real-time practical usability. Cloud integration provides scalability and ubiquitous access to our approach. Our experiments on extensive image data set of healthy and unhealthy leaves of fruits and vegetables showed an accuracy of 98.78% with a real-time diagnosis of plant leaves diseases. We used forty thousand images for the training of deep learning model and then evaluated it on ten thousand images. The process of testing an image for disease diagnosis and classification using A.W.S. DeepLens on average took 0.349s, providing disease information to the user in less than a second.
Risk Management for Defense Systems in a Complex, Dynamic Environment
Authors: Kordova Sigal
Published: September 2020

Identifying and assessing risk is one of the most important processes in managing complex systems and requires careful consideration. The need for an effective, efficient approach to risk management is considerably more important for defense projects based on systems of systems (SoS), because they are exposed to risk already in early stages of development. This paper uses advanced data science tools to present the complexity of the risk factors relevant to defense systems, and proposes a methodology for identifying, analyzing and monitoring the risks that they face. Findings from an in-depth analysis of 46 classified defense projects based on SoS shows a need to focus on three main risks faced by defense projects: uncertainty, the lack of clearly defined goals, and managing a system under constrained conditions. The paper also presents some recommendations for minimizing risk factors in SoS for defense projects.
Customer Satisfaction Assessment of E-Supply Chain Quality in Online Shopping: A Case Study
Authors: Abdirad Maryam , Krishnan Krishna
Published: September 2020

The purpose of this study is to examine the influence of Services Quality (SQ) of E-Supply Chain (E-SC) on customer satisfaction (CS) in online shopping. After a comprehensive review of the literature, the key factors of E-SC, CS, and SQ identification were selected. Then, the proposed conceptual model was presented. To validate this model, the data was collected through a survey of 150 respondents to diagnose customers’ satisfaction including online customers of “Digikala” online websites in Iran. The model was examined based on the partial least square-structural (PLS). Sample data was analyzed using SPSS21 and PLS. The proposed model was validated using factor analysis and structural equation modeling techniques. The results indicated that E-supply chain management(E-SCM) has a direct impact on CS. The effect of SQ is also confirmed. There is a positive and significant relationship between E-SCM and CS, E-SCM and SQ, and also, SQ and CS (P> 0.05).
Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells
Authors: Tishchenko Alexander , Domínguez Azorín Daniel , Vidal-Brime Laia , Muñoz María José , Arenas Pol Jiménez , Pearce Christopher , Girao Henrique , Ramón y Cajal Santiago , Aasen Trond
Published: September 2020

Connexin 43 (Cx43) forms gap junctions that mediate the direct intercellular diffusion of ions and small molecules between adjacent cells. Cx43 displays both pro- and anti-tumorigenic properties, but the mechanisms underlying these characteristics are not fully understood. Tunneling nanotubes (TNTs) are long and thin membrane projections that connect cells, facilitating the exchange of not only small molecules, but also larger proteins, organelles, bacteria, and viruses. Typically, TNTs exhibit increased formation under conditions of cellular stress and are more prominent in cancer cells, where they are generally thought to be pro-metastatic and to provide growth and survival advantages. Cx43 has been described in TNTs, where it is thought to regulate small molecule diffusion through gap junctions. Here, we developed a high-fidelity CRISPR/Cas9 system to knockout (KO) Cx43. We found that loss of Cx43 expression was associated with significantly reduced TNT length and number in breast cancer cell lines. Notably, secreted factors present in conditioned medium stimulated TNTs more potently when derived from Cx43-expressing cells than from KO cells. Moreover, TNT formation was significantly induced by inhibition of several key cancer signaling pathways that both regulate Cx43 and are regulated by Cx43, including RhoA kinase (ROCK), protein kinase A (PKA), focal adhesion kinase (FAK), and p38. Intriguingly, drug-induced stimulation of TNTs was more potent in Cx43 KO cells than in wild-type cells. In conclusion, this work describes a novel non-canonical role for Cx43 in regulating TNTs, identifies key cancer signaling pathways that regulate TNTs in this setting, and provides mechanistic insight into a pro-tumorigenic role of Cx43 in cancer.
The Questions of Who, What, and How in the Science - Policy Dialogue: Experiences from the Pan - Canadian Framework on Clean Growth and Climate Change
Authors: Pham Ha
Published: September 2020

The science‐policy interface in climate change adaptation became better managed over the past decades. However, the scientists and other knowledge producers, as well as policy makers still need to take bolder steps to more effectively engage with others to apply science and shape up policies. This paper aims to provide practical recommendations, intended to promote conversations between science and policy sectors to address climate change issues. Here, I used two different approaches to synthesize experiences and identify recommendations: a literature review and a case study. The paper stress main findings: (1) The linear communication model is still commonly involved in the science - policy dialogue and proved to be useful to increase the relevance of science and data products to decision makers. (2) When a gap between knowledge producer and knowledge user or decision maker exists, the need for a third party to specialize in bridging the gap become essential. (3) Indigenous people and knowledge must be involved in adaptation policy making based on legitimation local and traditional knowledge, designing the consultation process to broadly engage local and indigenous people, facilitating meaningful dialogues between traditional knowledge and science, and developing initiatives to strengthen skills and capacity of indigenous communities.
Aquatic Biota is Not Exempt from Coronavirus Infections: An Overview
Authors: NÚÑEZ-NOGUEIRA GABRIEL , Granados-Berber Andres Arturo
Published: September 2020

Coronaviruses are pathogens recognized for having an animal origin and commonly associated with terrestrial environments. However, although in few cases, there are reports of their presence in aquatic organisms like fish, crustaceans, waterfowls and marine mammals. None of these cases have even led to human health effects, when contact with these infected organisms, whether they are alive or dead. Aquatic birds seem to be the main group in carrying and circulating these types of viruses in healthy bird populations and play an important role in these environments. Although the route of infection for CoVID-19 (Coronavirus disease 2019) by water or aquatic organisms, has not yet been observed in the wild, the relevance of its study is highlighted , because there are cases of other viral infections (no coronavirus), which are known to have been transferred to the human by aquatic biota. What is even better, it becomes encouraging to know that aquatic species shows very few cases in fishes, marine mammals, and crustaceans, and some other aquatic animals may also be a possible source of cure or treatment against coronaviruses, as some evidence with algae and marine sponges suggests.
Fixed Circle and Fixed Disc Results for New Type of Qc-Contractive Mappings in Metric Spaces
Authors: Sessa Salvatore , Saleh Hayel N. , Alfaqih Waleed M. , Imdad Mohammad , Mlaiki Nabil
Published: September 2020

This paper aims to introduce the notions of various types of Qc-contractions for which we establish some fixed circle and fixed disc theorems in the setting of metric spaces. Some illustrative examples are also provided to support our results. Moreover, we present some fixed circle and fixed disc results of integral type contractive self-mappings.
Inflation Model and Riemann Tensor on Non-Associative Algebra
Authors: Dorofeev Vjacheslav
Published: September 2020

In this article the reduction of a $n$-dimensional space to a $k$-dimensional space is considered as a reduction of $N^n$ states to $N^k$ states, where $N$ stands for the number of single-particle states per unit of spatial length. It turns out, this space reduction could be understood as another definition of inflation. It is shown that the introduction of the non-associativity of the algebra of physical fields in a homogeneous space leads to a nonlinear equation, the solutions of which can be considered as two-stage inflation. Using the example of reduction $T\times R^7$ to $T\times R^3$, it is shown that there is a continuous cross-linking of the Friedmann and inflationary stages of algebraic inflation at times $10^{-15}$ with the number of baryons $10^{80}$ in the Universe. In this paper, we construct a new gravitational constant based on a nonassociative octonion algebra.
Synchronous Roundabouts with Rotating Priority Sectors (SYROPS) : High Capacity and Safety for Conventional and Autonomous Vehicles
Authors: Ibanez Guillermo , Meuser Tobias , Lopez-Carmona Miguel A. , Lopez-Pajares Diego
Published: September 2020

Roundabouts need capacity and safety improvements compatible with manual-driven, not only with autonomous vehicles. The signaling and control of roundabouts must evolve and incorporate current technologies. For that, we approach roundabouts as synchronous switches of vehicles. This paper describes Synchronous Roundabouts with Rotating Priorities, a roundabout control system based on vehicle platoons arriving at the roundabout at speed identical to the roundabout and within the time slot assigned to their entry, avoiding conflicts and stops, thus increasing roundabout capacity and safety. Signaling is visual for human drivers and also wireless for connected and autonomous vehicles. We evaluate analytically and with simulations roundabouts of different radius for several values of the average distance between vehicles. Average delays are 28,7 % lower, with negligible dispersion. The capacity improvements depend on design parameters: in our set is moderate for small roundabouts but goes up to 70-100 % for short distances and medium and large roundabouts.
Supersymmetric Mirror Models and Dimensional Evolution of Spacetime
Authors: Tan Wanpeng
Published: September 2020

A dynamic view is conjectured for not only the universe but also the underlying theories in contrast to the convectional pursuance of single unification theory. As the 4 -d spacetime evolves dimension by dimension via the spontaneous symmetry breaking mechanism, supersymmetric mirror models consistently emerge one by one at different energy scales and scenarios involving different sets of particle species and interactions. Starting from random Planck fluctuations, the time dimension and its arrow are born in the time inflation process as the gravitational strength is weakened under a 1-d model of a “timeron” scalar field. The “ timeron” decay then starts the hot big bang and generates Majorana fermions and U(1) gauge bosons in 2-d spacetime. The next spontaneous symmetry breaking results in two space inflaton fields leading to a double space inflation process and emergence of two decoupled sectors of ordinary and mirror particles. In fully extended 4-d spacetime, the supersymmetric standard model with mirror matter before the electroweak phase transition and the subsequent pseudo-supersymmetric model due to staged quark condensation as previously proposed are justified. A set of principles are postulated under t his new framework. In particular, new understanding of the evolving supersymmetry and Z2 or generalized mirror symmetry is presented.
Energy Analysis and Exergy Optimization of Photovoltaic-Thermal Collector
Authors: Kallio Sonja , Siroux Monica
Published: September 2020

A photovoltaic-thermal (PVT) collector is a solar-based micro-cogeneration system which generates simultaneously heat and power for buildings. The novelty of this paper is to conduct energy and exergy analysis on PVT collector performance under two different European climate conditions. The performance of the PVT collector is compared to a PV panel. Finally, the PVT design is optimized in terms of thermal and electrical exergy efficiencies. The optimized PVT designs are compared to the PV panel performance as well. The main focus is to find out if the PVT is still competitive with the PV panel electrical output, after maximizing its thermal exergy efficiency. The PVT collector is modelled into Matlab/Simulink to evaluate its performance under varying weather conditions. The PV panel is modelled with the CARNOT toolbox library. The optimization is conducted using Matlab gamultiobj-function based on Non-Dominated Sorting Genetic Algorithm-II (NSGA-II). The results indicated 7.7% higher annual energy production in Strasbourg. However, the exergy analysis revealed a better quality of thermal energy in Tampere with 72.9% higher thermal exergy production. The electrical output of the PVT is higher than from the PV during the summer months. The thermal exergy- driven PVT design is still competitive compared to the PV panel electrical output.
Acceptability, Adherence and Retention of a Feasibility Randomised Trial on Periodontal Treatment and Vitamin D/ Calcium Milk Fortification among Pregnant Women: A Mixed-Methods Evaluation
Authors: Adegboye Amanda Rodrigues Amorim , Dias Santana Danilo , Guedes Cocate Paula , Benaim Camila , Teixeira dos Santos Pedro Paulo , Heitmann Berit L , da Veiga Soares de Carvalho Maria Claudia , Maia Schlussel Michael , Trindade de Castro Maria Beatriz , Kac Gilberto
Published: September 2020

This study aims to assess the acceptability, adherence, and retention of a feasibility trial on milk fortification with calcium and vitamin D (Ca+VitD) and periodontal therapy (PT) among low income Brazilian pregnant women with periodontitis (IMPROVE trial). This 2x2 factorial feasibility trial used a mixed-methods evaluation. 69 pregnant women were randomly allocated to four groups: 1.fortified sachet with Ca+VitD and milk plus early PT (throughout gestation); 2.placebo and milk plus early PT; 3.fortified sachet with Ca+VitD and milk plus late PT after childbirth; 4.placebo and milk plus late PT. Data were collected via questionnaires, field notes, participant flow logs, treatment diary, and focal group discussions. Quantitative and qualitative data were analysed using appropriate descriptive statistics and content analysis, respectively. Eligibility rate (12%) was below the target of 15%, but participation (76.1%) and recruitment rate (2 women/week) exceeded the targets. Retention rate (78.6%) was slightly below the target (80%). Adherence to the PT was significantly higher in the early treatment groups (98.8%) compared to the late treatment groups (29%). All women accepted the random allocation and baseline groups were balanced. There was no report of adverse events. This multi-component intervention is acceptable, well-tolerated, and feasible among low-risk pregnant women in Brazil.
Ineffectual Regulation When An Official of A Regulatory Agency Seems to Regulate Effectually Without Actually Doing So
Authors: Oldberg Terry
Published: September 2020

Occasionally, officials of the world’s regulatory agencies embark upon attempts at bringing previously unregulated physical systems under regulation by them. Each such attempt raises an epistemological issue. At issue is whether enough information about the outcomes of the events of the future, given the outcomes of the events of the present, will be in the hands of a would-be regulator for this regulator to regulate effectually. If present, this information is provided by runs of a model of the physical system that is slated for regulation. Ideally, this model makes an argument that draws its conclusion from the evidence presented to it. If so, this argument is of the form of a predictive inference. However, the process by which an argument draws its conclusion from the evidence may go awry. This happens, for example, when the axiom of probability theory called unit measure is falsified by a conclusion that is drawn from the evidence by this argument.A method is derived from first principles for determination of whether unit measure is satisfied or falsified by an argument made by a model, given that this argument may attach unusual meanings to statistical terms. This method is used in a study of whether unit measure is satisfied or falsified by the arguments that are made by a pair of models. Both models are in active use by regulatory agencies around the world. Under neither argument do runs of the model provide an official of a regulatory agency with the information gain aka mutual information that he or she would need to regulate effectually. Under both arguments, attachment of unusual meanings to statistical terms creates the illusion that such an official can and does regulate effectually.
Discrete Modulation Source Enhancement for Continuous Variable Quantum Key Distribution through Photon Catalyzing
Authors: Zhou Zhengchun , Zou Shanhua , Mao Yun , Huang Tongcheng , Guo Ying
Published: September 2020

Establishing global high-rate secure communications is a potential application of continuous-variable quantum key distribution (CVQKD) but also challenging for long-distance transmissions in metropolitan areas. The discrete modulation(DM) can make up for the shortage of transmission distance that has a unique advantage against all side-channel attacks, however its further performance improvement requires source preparation in the presence of noise and loss. Here, we consider the effects of photon catalysis (PC) on the DM-involved source preparation for lengthening the maximal transmission distance of the CVQKD system. We address a zero-photon catalysis (ZPC)-based source preparation for enhancing the DM-CVQKD system. The statistical fluctuation due to the finite length of data is taken into account for the practical security analysis. Numerical simulations show that the ZPC-based DM-CVQKD system can not only achieve the extended maximal transmission distance, but also contributes to the reasonable increase of the secret key rate. This approach enables the DM-CVQKD to tolerate lower reconciliation efficiency, which may promote the practical implementation solutions compatible with classical optical communications using state-of-the-art technology.
Are Health Innovations Techno-economic or Social Values in a period of a Health Crisis? A Reflection on the Field of Public Health through the Examples of Ebola and Covid-19
Authors: Niang Marietou , Dupéré Sophie , Alami Hassane , Gagnon Marie-Pierre
Published: September 2020

Health innovations are generally oriented on a techno-economic vision. In this perspective, technologies are seen as an end in themselves, and there is no arrangement between the technical and the social values of innovation. This vision prevails in sanitary crises, in which management is carried out based on the search for punctual, reactive, and technical solutions to remedy a specific problem without a systemic/holistic, sustainable, or proactive approach. This paper attempts to contribute to the literature on the epistemological orientation of innovations in the field of public health. Taking the Covid-19 and Ebola crises as examples, the primary objective is to show how innovation in health is oriented towards a techno-economic paradigm. Second, we propose a repositioning of public health innovation towards a social paradigm that will put more emphasis on the interaction between social and health dimensions in the perspective of social change.
Ain’t too Proud to Beg! Effects of Leader’s Use of Pride on Groups
Authors: Baumgartner Steve , Daus Catherine
Published: September 2020

Studies of discrete pride in the workplace are both few and on the rise. We examined what has, to date, been yet unstudied: the impact that a leader’s expressions of authentic and hubristic pride can have on the followers at that moment, and on their feelings about their task, leader, and group. Students working in groups building Lego structures rated their perceived leader regarding expressions of pride, both authentic and hubristic. Students who perceived the leader as expressing more authentic pride rated the task, group (satisfaction and cohesion), and leader more positively; while the reverse was generally true for perceptions of expressions of hubristic pride. We found these effects both at the individual level, and at the group level. We also predicted and found moderation for the type of task worked on, creative or detailed. Implications abound for leader emotional labor and emotion management.
Low-dose Whole-lung Irradiation for COVID-19 Pneumonia: What is the Optimal Dose? Final Results of a Pilot Study
Authors: Ameri Ahmad , Ameri Pooya , Rahnama Nazanin , Mokhtari Majid , Sedaghat Meghdad , Hadavand Fahimeh , Bozorgmehr Rama , Haghighi Mehrdad , Taghizadeh-Hesary Farzad
Published: September 2020

Purpose: Novel coronavirus disease (COVID-19) is the current global concern. Radiotherapy (RT), commonly employed in cancer management, has been considered one of the potential treatments for COVID-19 pneumonia. Here, we present the final report of the pilot trial evaluating the efficacy and safety of low-dose whole-lung irradiation (LD-WLI) in patients with COVID-19 pneumonia. Methods and Materials: We enrolled patients with moderate COVID-19 pneumonia who were older than 60 years. Participants were treated with LD-WLI in a single fraction of 0.5 or 1.0Gy along with the national protocol of COVID-19. The primary endpoints were improvement of SpO2, the number of hospital/ICU stay days, and the number of intubations after RT and the secondary endpoints were alterations of the c-reactive peptide, interleukin-6, ferritin, procalcitonin, and D-dimer. The response rate (RR) was defined as a rise in SpO2 upon RT with rising or constant trend in the next two days, and clinical recovery (CR) included patients who were discharged from the hospital or acquired SpO2 ≥93% on room air. Results: Between 21 May 2020 and 2 July 2020, ten patients were enrolled. The median age was 75 years, 80% were male, and 80% had comorbidities. The first five patients received a single 0.5Gy-WLI, and others received 1.0Gy. Patients were followed for 2-14 days (median 5.5 days). Following one day, nine patients experienced an improvement in SpO2. Five patients were discharged (median 6th day, range 2nd-14th day), and four patients died (median 7th day, range 3rd-10th day). Overall, the RR and CR were 60.0% and 55.5%, respectively. The RR and CR rates of 0.5- and 1.0Gy group were 80% vs 40% and 75% vs 40%, respectively. No acute radiation-induced toxicity was recorded. Conclusions: LD-WLI with a single 0.5Gy fraction seems to be a more appropriate dose to warrant further evaluation in a large-scale, randomized trial.
Technical and Economic Feasibility of a Stable Yellow Natural Colorant Production from Waste Lemon Peel
Authors: Ciriminna Rosaria , Forest Billy , Meneguzzo Francesco , Pagliaro Mario , Hamann Mark
Published: September 2020

A brief technical and economic insight into producing the water-soluble yellow colorant limocitrol 3-O-6”-[3-hydroxyl-3-methylglutaryl)])-β-D-glucopyranoside from waste lemon peel via simple solid-liquid extraction in aqueous ethanol or via hydrodynamic cavitation of waste lemon peel in water, shows that the biocolorant can be obtained at affordable cost. Coupled to the simplicity and sustainability of the extraction processes suggested, the high chemical and physical stability of this polymethoxylated flavanol and the health benefits of citrus flavonoids, support industrialization of this new bioeconomy production.
The Advance of Planets' Perihelion in Newtonian Theory Plus Gravitational and Rotational Time Dilation
Authors: Corda Christian
Published: September 2020

It is shown through three different approaches that, contrary to a longstanding conviction older than 160 years, the orbit of Mercury behaves as required by Newton's equations with a very high precision if one correctly analyzes the situation in the framework of the two-body problem without neglecting the mass of Mercury. General relativity remains more precise than Newtonian physics, but the results in this paper show that Newtonian framework is more powerful than researchers and astronomers were thinking till now, at least for the case of Mercury. The Newtonian formula of the advance of planets' perihelion breaks down for the other planets. The predicted Newtonian result is indeed too strong for Venus and Earth. Therefore, it is also shown that corrections due to gravitational and rotational time dilation, in an intermediate framework which analyzes gravity between Newton and Einstein, solve the problem. By adding such corrections, a result consistent with the one of general relativity is indeed obtained. Thus, the most important results of this paper are two: i) It is not correct that Newtonian theory cannot predict the anomalous rate of precession of the perihelion of planets' orbit. The real problem is instead that a pure Newtonian prediction is too strong. ii) Perihelion's precession can be achieved with the same precision of general relativity by extending Newtonian gravity through the inclusion of gravitational and rotational time dilation effects. This second result is in agreement with a couple of recent and interesting papers of Hansen, Hartong and Obers. Differently from such papers, in the present work the importance of rotational time dilation is also highlighted.
Tumoral HLA Class I and APM Expression and Its Effect on Intratumoral T-cell Reaction and Outcome in HPV-Negative Oral Squamous Cell Carcinoma
Authors: Wickenhauser Claudia , Bethmann Daniel , Kappler Matthias , Eckert Alexander Walter , Steven André , Bukur Juergen , Fox Bernard A. , Beer Jana , Seliger Barbara
Published: September 2020

Progression of oral squamous cell carcinoma (OSCC) has been associated with an escape of tumor cells from the host immune surveillance with growing evidence of its underlying molecular mechanisms and its interaction with the immune cell control. In this study the expression of HLA class I (HLA-I) antigens and of components of the antigen processing machinery (APM) was analyzed in 160 consecutive human papilloma virus (HPV)-negative OSCC lesions and correlated to tumor specific parameters, the intratumoral immune cell response and to the patients outcome. A heterogeneous, but predominantly lower constitutive protein expression of HLA-I APM components was seen in OSCC sections when compared to non-neoplastic cells. Based on the expression levels of HLA-I APM components three main OSCC subgroups were detected and categorized into HLA-Ihigh/APMhigh, HLA-Ilow/APMlow and HLA-Idiscordant high/low/APMhigh phenotypes. In the HLA-Ihigh/APMhigh group, the highest frequency of intratumoral CD8+ T cells and lowest number of CD8+ T cells close to FoxP3 cells was found. Despite being associated with the highest T cell infiltration, patients within this group presented the most unfavorable survival, which was most evident in stage T2 tumors. Thus, the presented findings strongly indicate the presence of additional factors involved in the immunomodulatory process of HPV-negative OSCC with a possible tumor-burden-dependent complex network of immune escape mechanisms beyond HLA-I/APM components and T cell infiltration in this tumor entity.