bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluación de la propuesta de enseñanza de las áreas de lenguaje y matemáticas en la Institución Educativa San José del Pantano
Authors: Díaz Alex Mauricio
Published: November 2016

El propósito de este artículo es presentar los avances de un estudio tendiente a evaluar el impacto del programa Todos a Aprender en los procesos de enseñanza del lenguaje y las matemáticas en los docentes de básica primaria de la Institución Educativa San José del Pantano del municipio de Puerto Escondido, en el departamento de Córdoba. Esta investigación tiene un enfoque cualitativo, con un diseño de estudio de caso, con tres categorías de análisis: comunidad de aprendizaje de docentes, metodología del estudio de clases y desarrollo profesional situado. Para su desarrollo, se tienen en cuenta las siguientes fases: proyección de las comunidades de aprendizaje, ejecución del desarrollo profesional situado y consolidación de la comunidad de aprendizaje de docentes. Se muestran los resultados obtenidos acerca la formación docente y el análisis comparativo de las pruebas saber de los grados 3º y 5º durante 2014.
Fibroblast Growth Factor 23 and the Risk of Infection-Related Hospitalization in Older Adults
Authors: Nowak Kristen L. , Bartz Traci M. , Dalrymple Lorien , de Boer Ian H. , Kestenbaum Bryan , Shlipak Michael G. , Garimella Pranav S. , Ix Joachim H. , Chonchol Michel
Published: November 2016

Within monocytes, 1,25-dihydroxyvitamin D [1,25(OH)2D] is important for production of cathelicidins, which in turn, are critical for antibacterial action. Fibroblast growth factor 23 (FGF23) decreases 1,25(OH)2D production and thus, could increase infection risk. We examined this possibility in 3141 community-dwelling adults ages ≥65 years old at baseline in the Cardiovascular Health Study using Cox proportional hazards models to examine the association between FGF23 concentrations and first infection-related hospitalizations and determine whether associations differed by the presence of CKD (eGFR<60 ml/min per 1.73 m2 [n=832] or urine albumin-to-creatinine ratio >30 mg/g [n=577]). Mean±SD age of participants was 78±5 years old, 60% of participants were women, and the median plasma FGF23 concentration was 70 (interquartile range, 53–99) relative units per milliliter. In fully adjusted models, higher FGF23 concentrations associated with higher risk of first infection-related hospitalization (hazard ratio [HR], 1.11; 95% confidence interval [95% CI], 1.03 to 1.20 per doubling of FGF23) during a median follow-up of 8.6 years. In participants with or without CKD (defined by eGFR), FGF23 concentration associated with first infection-related hospitalization with HRs of 1.24 (95% CI, 1.08 to 1.42) and 1.06 (95% CI, 0.97 to 1.17) per doubling of FGF23, respectively (P=0.13 for interaction). Associations did not differ between groups when stratified by urine albumin-to-creatinine ratio. In sensitivity analyses, the addition of serum calcium, phosphorus, 25-hydroxyvitamin D, intact parathyroid hormone, and 24,25-dihydroxyvitamin D did not meaningfully change the estimates. In conclusion, in community-dwelling older adults, higher plasma FGF23 concentrations independently associated with the risk of first infection-related hospitalization.
Salud, espiritualidad y calidad de vida: Una aproximación desde la Facultad de Enfermeríar
Authors: Plata de Silva Rita Cecilia
Published: November 2016

Editorial
Factores clínicos asociados a la hipertensión arterial severa posparto: un estudio de casos y controles en la Clínica San Luis, Bucaramanga, Colombia
Authors: Ospina G. Sandra Cecilia , Núñez M. Andrés Felipe
Published: November 2016

Este estudio observacional analítico de casos y controles de base hospitalaria, con información obtenida de historias clínicas, busca determinar los factores clínicos asociados a la hipertensión arterial severa posparto y la magnitud de dicha asociación en la población obstétrica que ingresó entre 2010 y 2012 a la Clínica Materno Infantil San Luis, Bucaramanga, Colombia. Los casos fueron mujeres con parto atendido en dicha institución en ese periodo y diagnosticadas con hipertensión arterial severa puerperal,incluidas quienes se diagnosticaron en el posparto antes de su egreso hospitalario o en un reingreso.

Los controles se seleccionaron aleatoriamente y corresponden a mujeres con parto atendido en la Clínica durante el mismo periodo y que no presentaron hipertensión arterial severa puerperal. Se excluyeron historias clínicas incompletas, mujeres con lupus eritematoso sistémico o que recibieron bromocriptina o derivados del ergot durante el parto o puerperio. Se analizaron variables demográficas y clínicas. Se calculó una muestra de 327 gestantes (163 por grupo), para una prevalencia de hiperuricemia anteparto del 2% como principal variable de exposición a evaluar; un nivel de significancia del 5%, un poder del 80%, una precisión de 1,5% y un efecto de diseño de 1,0. Se incluyeron 446 maternas, 222 casos y 224 controles. La hipertensión gestacional RM 3,19 (IC 95% 1,88-5,41) y la hiperuricemia anteparto RM 2,68 (IC 95% 1,29-5,55) fueron variables de riesgo para el desenlace. Se concluye que la hipertensión gestacional y la hiperuricemia anteparto son las principales variables de riesgo para hipertensión arterial severa puerperal.
Comparación de prácticas en salud sexual y reproductiva entre estudiantes de Ciencias de la Salud y de ingeniería de una institución de educación superior en Bogotá, Colombia, 2008
Authors: Ibáñez P. Edgar Antonio , Guarnizo-Tole Mildred
Published: November 2016

El objetivo de este estudio de corte transversal fue comparar las prácticas en salud sexual y reproductiva de un grupo de estudiantes de ciencias de la salud y de ingeniería de una institución de educación superior en Bogotá, Colombia, en el año 2008. El tamaño de la muestra fue de 112 estudiantes de ciencias de la salud y 109 estudiantes de ingeniería. El 72% de los estudiantes de ingeniería y el 67,9% de ciencias de la salud tuvieron su primera relación sexual entre los 15 y 18 años. La frecuencia de embarazos es mayor en las estudiantes de ciencias de la salud (20% vs. 7,6%). El nivel de conocimientos en anticoncepción fue superior en los estudiantes de ciencias de la salud (74,1% vs. 50,5%). Se presentan similitudes en el nivel de conocimiento sobre las infecciones de transmisión sexual, 96,4% en ciencias de la salud y 92,7% en ingeniería. No se realizan la citología cervicouterina: 69,4% de las estudiantes de las ciencias de la salud y 61,9% de ingeniería. El 85,7% de los hombres en las ingenierías y el 58,3% de las ciencias de la salud no realizan el autoexamen de testículo. Se concluye que, pese a que los estudiantes de ciencias de la salud tienen un mayor nivel de conocimiento relacionado con la salud sexual y reproductiva, los resultados indican similitudes al compararlos con ingeniería; por lo tanto, tener formación en este aspecto no siempre significa que estos conocimientos sean llevados a la vida propia para el ejercicio de una sexualidad responsable.
EKONOMI LUMBUNG DAN KONSTRUKSI KEBERDAYAAN PETANI MUSLIM MADIUN
Authors: Arifin Sirajul , Izzuddin Muhammad Andik
Published: November 2016

Muslim farmers of Luworo Madiun often suffer from the hegemony of ijon (debtbondage) system. The system which exploits and weakens the farmers can no longer be tolerated, but should be responded through the construction of lumbung (barn; place for rice storage). The lumbung which is constructed next to mosque can become an important asset for creating food security and solving the economic problems of the farmers. However, lumbung asset will not survive or develop if not supported by other assets. The mosque, market, agricultural area, and society itself all are important assets developed by the farmers of Luworo to strengthen the survival and development of lumbung asset. The lumbung then has power not only to build food security but also to strengthen the economic capacity of society. This economic power is developed through the construction of lumbung which gives equal rights to all members, in contrast to the unjust and exploitative ijon system.
PERAN SERTA LEMBAGA PENDIDIKAN TINGGI DI KOTA SEMARANG DALAM MENDORONG PERTUMBUHAN PERBANKAN SYARI’AH DI KOTA SEMARANG
Authors: Suwanto Suwanto
Published: November 2016

The purpose of this research is intended to determine the role of the IAIN Walisongo Semarang in encouraging the growth of sharia banking in Semarang. A descriptive qualitative method is applied in order to obtain data in this study through collecting and analyzing the related literature to this research. Moreover observation, interviews and secondary data on the development of Islamic banking from sharia banking statistic Indonesian Banking are caried out. The finding shows that the IAIN Walisongo Semarang has a role in encouraging the growth of sharia banking in Semarang through the development discourse and discipline of Islamic economics to open a graduate studies program of applied science of Islamic banking, the establishment of Islamic financial institutions BMT Walisongo, cases and the concept of derivation Development Sharia Banking, Products and Services, Socialization, and Human  Resource Competencies, Roles in providing competence human resources on Islamic banking, Development and Assistance to financing customers, dissemination of Islamic banking in the community, cooperation with agency of Sharia Financing, involvement of State Polytechnic of Semarang in Islamic banking in financing, and Encouraging society become customer of Islamic Banking. Finally the higher education institutions in Indonesia have an opportunity to meet the needs of Islamic banking industry through the activities of Tri Darma Perguruan Tinggi, especially to help the business sectors to alleviate the problems derivation and translation of national rules of Islamic Banking, products and services, socialization, and human resource competencies.
PERBANDINGAN IMBAL HASIL KONTRAK MUDHARABAH DAN PARTISIPASI MODAL DALAM PENGHIMPUNAN DANA BANK SYARIAH DI INDONESIA
Authors: Amaroh Siti
Published: November 2016

This study aims to compare the return between mudharabah deposits and equityparticipating in Indonesia Islamic banking and also to examine the factors that affect the returns. Employee monthly data of 3 Islamic banks over the period 2006-2011 and examined by regression panel model. This research results several substantial findings. First, return on mudharabah deposits is lower than return on equity participating. Second, return on mudrabah deposits is significantly affected by return on assets, profit attributable to third party deposits as percentage of operating profit, and total deposit to total assets. Third, return on equity is also significantly affected by return on assets, profit attributable to equity holders as a percentage of operating profit, and total equity to total assets. Fourth, return on assets affects more higher return on equity than the return on mudharabah deposits.
STUDI EMPIRIS ATAS ABSOLUTE INCOME HYPOTHESIS DAN PERMANENT INCOME HYPOTHESIS DALAM PERSPEKTIF ISLAM
Authors: Bawono Anton
Published: November 2016

Conventional consumption theory has complementary development and correct to one another. In this study, the aims include religiosity variable determinant of consumption, the household consumption behavior of Muslims. The analysis tool used is multiple regressions. Research findings indicate that religiosity variables have the most dominant and significant influence. While the other variables are also significant is the variable income, wealth and the wealth of productive smoothly the current period. The most dominant religiosity variable coefficients, because the more religious a Muslim will increasingly think of consumption the interests others in need, as it has a good prospect in the world in life and after death, in accordance with the guidance in the Qur’an and the Sunnah of the Prophet.
PENGARUH PEMAHAMAN AGAMA, MOTIFASI MENDAPATKAN PROFIT DAN TINGKAT PENDIDIKAAN TERHADAP KESADARAN SERTIFIKASI HALAL BAGI PRODUSEN MAKANAN DI KABUPATEN SLEMAN DAN BANTUL
Authors: Waluyo Waluyo
Published: November 2016

This research aims to determine whether there is an understanding of the influence of religion, profit motivation and education levels of the awareness of certified halal food for producers in Sleman and Bantul, as well as to find among the independent variables which are more significant. This research is a quantitative study with multiple regression analysis. Independent variables (religious understanding, motivation and profit levels) simul-taneously have significant effect on awareness of halal certification for food producers in Sleman and Bantul with the amount of influence of 66.7%. The independent variables that have a significant effect on the dependent variable  (motivation of certified halal) is understanding of religion variable and profit motivation.
LISTENING FROM THE BOTTOM A QUALITATIVE APPROACH EXAMINING ZAKAT RECIPIENTS’ VOICES
Authors: Lessy Zulkipli
Published: November 2016

Existing zakat research, reports little information about the living conditions of Indonesian zakat recipients. This study examined the perceptions of zakat recipients at Rumah Zakat, a charitable institution, in Yogyakarta. Semi-structured interviews solicited seven economic empowerment program respondents’ narratives. This data collection method incorporating a phenomenological approach to data analysis revealed that respondents with more education and spousal support could better subsist after utilizing Rumah Zakat’s interest-free loans, and compared to individual efforts or group support, spousal support helped significantly with business growth. These respondents typically earned incomes above the national standard of poverty. As their businesses grew, four respondents planned to employ the jobless. Respondents benefiting from the program reported significant impact on their home economies and social lives.
PENGARUH SPIRITUALITAS, INTELEKTUALITAS, DAN PROFESIONALISME TERHADAP KINERJA DOSEN STAIN SALATIGA
Authors: Nugraha Pratama Abdul Aziz
Published: November 2016

This study aims to determine the effect of each variable spirituality, intellect, and professionalism of the lecturers performance STAIN Salatiga. The population of this study are all tenured State Institute of Islamic Studies (STAIN) Salatiga as many as 107 people. The sampling technique used in this study using simple random sampling and 65 were taken as respondents. With quantitative methods and analysis techniques that use moderated regression analysis (MRA), it can be concluded that (1) spirituality is partially not significantly affect the performance of the faculty; (2) the partial intellect does not significantly affect the performance of the faculty; (3) professionalism partially positive and significant effect on the performance of the lecturer. (4) spirituality, intellect and professionalism of lecturers jointly affect the performance of the lecturer. The study also found that the majority of respondents aged very productive, but they are staying at very far away from the campus.
PENGARUH ETOS KERJA ISLAMI DAN GAYA KEPEMIMPINAN TERHADAP KINERJA KARYAWAN RUMAH MAKAN AYAM LEPAAS LHOKSEUMAWE
Authors: Desky Harjoni
Published: November 2016

The purpose of this study is to analyze and explain the significant influence of Islamic work ethic with employee performance.This study uses a quantitative approach. The type of this research is exploratory research study. The samplingtechnique in this study using census method. The technique used for conducting this research through documentation, interviews, and questionnaires.This research was done by using the census of 65 employees eating spicy chicken in Lhokseumawe. Data were collected through questionnaires, interviews and documentation further processed using descriptive analysis and Path. The results of the analysis show that: (1) Islamic work ethic and a significant positive effect on employee performance, (2) transformational leadership style and a significant positive effect on employee performance.
INFORMAL ARTICLES AND READING-WRITINGSPEAKING CYCLE IN EXTENSIVE READING (ER) PROGRAM: EFL LEARNERS’ PERCEPTION
Authors: Umam Chotibul
Published: November 2016

Informal article is one of authentic materials which may contain valuable informations and extensive input to develop the learners’ language proficiency. Unfortunately, most literature shows that informal articles are not widely used in Extensive Reading (henceforth ER) program. For this reason, in this micro-scale exploratory research, the writer would like to introduce the steps procedure in using informal articles in ERprogram for Indonesian EFL college learners and to investigate their perception toward the implementation of the procedure. The procedure is developed on the basis of the writer’s great interest in creating innovative way in teaching ER at Indonesian collegelevel. The procudure is then called as Reading-Writing-Speaking (RWS) cycle which comprises structured-steps. Although it has some shortcomings, the participants bestow positive perception and respectable comments toward the procedure. The proposedprocedure is expected to be an alternative pathway in teaching ER for English teachers particularly at a university level.
Cooptación y restitución de tierras geoestratégicas en Colombia y México a través de la construcción transnacional de comunidades identificadas con el narcotráfico
Authors: Arias Henao Diana Patricia
Published: November 2016

Artículo de reflexión cuyo objetivo principal es demostrar en el escenario del derecho internacional contemporáneo, las nuevas amenazas que representa el narcotráfico en lo que se refiere a la agenda de seguridad,  así como sus efectos sociales, económicos y culturales. Los Estados a comparar la amenaza: Colombia y México. La metodología es comparativa y como principales resultados, se dimensiona el de las comunidades identificadas con el narcotráfico y sus mercados de contrabando conexos, que se cimientan en la relación transnacional ilícita de redes narcotraficantes con vínculos estatales consolidados a través de la cooptación de los sistemas políticos y de seguridad. La región Caribe es el enclave geoestratégico para el comercio de narcóticos: zona de producción, de comercio al por mayor y lugar de distribución mediante pautas violentas, una especie de narco-incoterms.
Las enfermedades de transmisión sexual y la salud sexual del costarricense Tema I. SIDA/VIH
Authors: Gutiérrez-Sandí William , Blanco-Chan Christian
Published: November 2016

Las enfermedades de transmisión sexual (ETS) son causadas por más de 30 bacterias, virus y parásitos diferentes, y se propagan de manera predominante por contacto sexual, incluidos el sexo vaginal, anal y oral.

Algunas ETS se pueden propagar por contacto sexual cutáneo; los organismos causantes también lo hacen por medios no sexuales, como las transfusiones de productos sanguíneos y los trasplantes de tejidos. Muchas ETS, especialmente clamidiasis, gonorrea, hepatitis B, VIH, VPH, HSV2 y sífilis, se pueden transmitir también de la madre al niño durante el embarazo y el parto.

Una persona puede tener una ETS sin manifestar síntomas de la enfermedad. Por consiguiente, el concepto “infección de transmisión sexual” es más amplio que el de “enfermedad de transmisión sexual”. Los síntomas comunes de las ETS incluyen flujo vaginal, secreción uretral en los hombres, úlceras genitales y dolor abdominal.

Entre los más de 30 agentes patógenos que se transmiten por contacto sexual, ocho se han vinculado a la máxima incidencia de enfermedades. De esas ocho infecciones, cuatro son curables, a saber, sífilis, gonorrea, clamidiasis y tricomoniasis. Las otras cuatro, hepatitis B, herpes, VIH y VPH, son infecciones virales incurables que, no obstante, se pueden mitigar o atenuar con tratamiento.

El presente estudio se divulgará en tres partes que cubrirán las infecciones más comunes por bacterias, virus y hongos, así como los hábitos y cuidados que deben tener las personas con una vida sexual activa para no ser infectadas por alguna ETS. 

En esta primera parte se desarrolla el tema del SIDA/VIH y su impacto a nivel global, regional y nacional. Cada una de las entregas posteriores será un complemento del número anterior, de manera que se pueda ir instruyendo al lector en los cuidados y manejo de cada patología descrita.
Distance Learning for Food Security and Rural Development: A Perspective from the United Nations Food and Agriculture Organization
Authors: McLean Scott , Gasperini Lavinia , Rudgard Stephen
Published: November 2016

This article introduces the work of the United Nations Food and Agriculture Organization (FAO), and describes its interest in the application of distance learning strategies pertinent to the challenges of food security and rural development around the world. The article briefly reviews pertinent examples of distance learning, both from the experience of FAO and elsewhere, and summarises a complex debate about the potential of distance learning in developing countries. The paper elaborates five practical suggestions for applying distance learning strategies to the challenges of food security and rural development. The purpose of publishing this article is both to disseminate our ideas about distance learning to interested professional and scholarly audiences around the world, and to seek feedback from those audiences.
Online Education Systems in Scandinavian and Australian Universities: A Comparative Study
Authors: Paulsen Morten
Published: November 2016

This article presents a comparative study of online education systems in Norwegian, Swedish, and Australian universities. The online education systems discussed comprise content creation tools and systems for learning management, student management, and accounting. The author of this article arrives at the conclusion that there seems to be a general lack of integration between theses systems in all three countries. Further, there seems to be little focus on standards specifications such as IMS Global Learning Consortium (IMS) and Sharable Content Object Reference Model (SCORM) in higher education in all three countries. It was found that both Norway and Sweden value the importance of nationally developed learning management systems and student management systems; however, this does not seem to be the case in Australia. There also seems to be much more national coordination and governmental coercion concerning the choice of student management systems used in Sweden and Norway, than is the case in Australia. Finally, with regard to online education, the most striking difference between these three countries is that of economic policy. In Australia, education is considered an important export industry. In Norway and Sweden, however, the export of education does not seem to be an issue for public discussion.
When is a Learning Object not an Object: A first step towards a theory of learning objects
Authors: Sosteric Mike , Hesemeier Susan
Published: November 2016

For some, “learning objects" are the “next big thing” in distance education promising smart learning environments, fantastic economies of scale, and the power to tap into expanding educational markets. While learning objects may be revolutionary in the long term, in the short term, definitional problems and conceptual confusion undermine our ability to understand and critically evaluate the emerging field. This article is an attempt to provide an adequate definition of learning objects by (a) jettisoning useless theoretical links hitherto invoked to theorize learning objects, and (b) reducing the definition of learning objects to the bare essentials. The article closes with suggestions for further research and further refinement of the definition of learning objects.
Responsible environmental behavior intention of travelers on ecotourism sites
Authors: Handriana Tanti , Ambara Raya
Published: November 2016

The purpose – This research aims to investigate responsible environmental behavior intention of travelers formed upon visiting ecotourism sites in Indonesia. Nowadays, ecotourism has become a popular concept of tourism in Indonesia due to its rich potential of natural and cultural resources. Nevertheless, it is undeniable that not all travelers visiting ecotourism objects demonstrate positive environmental behavior. Several previous studies have already revealed that travelers’ behavior may alter after visiting tourism sites. Unfortunately, there has not been much discussion on travelers’ positive behavior formed after visiting an ecotourism site. In this research, four variables regarded as significant in shaping responsible environmental behavior intention included destination image, trip quality, perceived value, and satisfaction. Design/Methodology – This research applied a survey method. The research sample consisted of travelers who had visited ecotourism sites in Indonesia, while the number of respondents amounted to 210 travelers. Structural Equation Modeling (SEM) was selected as the technique of analysis. Finding – This research confirmed that five proposed hypotheses were supported. Hence, this study clearly contributes to the development of the theory and concept of ecotourism useful for practitioners associated with ecotourism activities. Originality of the research – Research on ecotourism in developing countries has not been much done. Similarly, the research on ecotourism related to intention to behave environmentally responsible is still not much to investigate, while the ecotorurism activities in Indonesia began in earnest. Therefore, research is expected to contribute ideas and implementation of ecotourism in developing countries.
Electronic word-of-mouth: successful communication strategies for restaurants
Authors: Fox Gavin , Longart Pedro
Published: November 2016

Purpose – A great deal has been discussed about the importance of using social media in marketing communications programmes because of mistrust in marketer-generated communications and more particularly for generating electronic word of mouth (e-WOM). However, it is not clear what types and styles of communication serve better the purpose using effectively social media for generating positive e-WOM. This study is aimed at exploring the types and styles of communication that work more effectively towards that purpose. Design – The study was conducted in Dublin, Ireland and is qualitative in nature. Methodology – This research involved semi-structured, in-depth interviews with restaurant marketers who currently use social media as part of the integrated marketing communications strategies; it also included a focus group and two sub-sequent personal interviews with restaurant consumers who actively use social media. Approach – A thematic analysis was conducted so as to first investigate the central topics surrounding the stimulation of positive e-WOM and styles and types of communication. Findings – Further analysis of the themes pointed to a number of practical implications which in turn led to the formulation of four (4) practical recommendations for restaurant marketers. Originality – This is the first practical paper that looks into the content, style and type of communication for effective stimulation of e-WOM in the restaurant context.
Resources and capabilities driving performance in the hotel industry
Authors: Božič Valentina , Knežević Cvelbar Ljubica
Published: November 2016

Purpose – The purpose of this paper is to provide an overview of the resources and capabilities framing sustainable competitive advantages in the hotel industry. Design – What is driving performance of firms is an on-going question evoking considerable interest among academics and practitioners alike. This has driven a large body of conceptual and empirical research. Empirical testing of sustainable competitive advantages driving performance in the hospitality industry has been one of the most researched topics in the last three decades. This paper summarises and reflects on those findings. Methodology – Paper uses content analysis to review the existing studies in order to understand resources and capabilities driving the performance in the hotel industry. Findings: Results show that most of the studies in the hospitality industry focus on investigating the impact of intangible resources and capabilities on hotel performance. In most of the cases studies use knowledge as a main driver of performance. Interestingly tangible resources are rarely considered and included in the research. Originality of the research – Literature has so far failed to provide a review paper summarising empirical results of many studies that explored drivers of hotels performance. This paper brings a theoretical contribution summarising and reflecting on the current body of knowledge.
TTF1, in the Form of Nanoparticles, Inhibits Angiogenesis, Cell Migration and Cell Invasion in VitroandIn Vivoin Human Hepatoma through STAT3 Regulation
Authors: Xiao Bin , Lin Dongjing , Zhang Xuan , Zhang Meilan , Zhang Xuewu
Published: November 2016

TTF1-NP(5,2′,4′-trihydroxy-6,7,5′-trimethoxyflavone nanoparticles), derived from the traditional Changbai Mountain medicinal plant Sorbaria sorbifolia (SS), has been showedits anti-cancer effect in various liver cancer cell types and tissues. The present study was designed to evaluate the antitumor mechanism of the TTF1-NP against HepG2 hepatoma cells and HepG2 cells-induced hepatocarcinoma (HCC) in nude mouse model. Here we demonstrated that TTF1-NP inhibits tube formation of HUVECs and HepG2 cell migration and invasion, and inhibits tumor growth in nude mice implanted with HepG2 cells through the downregulation of STAT3 protein and activation, along with VEGF, KDR, bFGF, MMP2 and MMP9 levels. We further revealed that TTF1-NP decreased the DNA-binding capacity of STAT3. Together our results provide a mechanism by which TTF1-NP suppresses cancer cell migration, invasion and angiogenesis through the action of STAT3 and suggests TTF1-NP as a potential therapy for hepatocellular cancer treatment.
Feature Extraction of Ship Radiated Noise Based on Permutation Entropy of the Intrinsic Mode Function with the Highest Energy
Authors: Li Yu-Xing , Li Ya-An , Chen Zhe , Chen Xiao
Published: November 2016

In order to solve the problem of feature extraction of underwater acoustic signals in complex ocean environment, a new method for feature extraction from ship radiated noise is presented based on empirical mode decomposition theory and permutation entropy. It analyzes the separability for permutation entropies of the intrinsic mode functions of three types of ship radiated noise signals, and discusses the permutation entropy of the intrinsic mode function with the highest energy. In this study, ship radiated noise signals measured from three types of ships are decomposed into a set of intrinsic mode functions with empirical mode decomposition method. Then, the permutation entropies of all intrinsic mode functions are calculated with appropriate parameters. The permutation entropies are obviously different in the intrinsic mode functions with the highest energy, thus, the permutation entropy of the intrinsic mode function with the highest energy is regarded as a new characteristic parameter to extract the feature of ship radiated noise. After that, the characteristic parameters, namely, the energy difference between high and low frequency, permutation entropy, and multi-scale permutation entropy, are compared with the permutation entropy of the intrinsic mode function with the highest energy. It is discovered that the four characteristic parameters are at the same level for similar ships, however, there are differences in the parameters for different types of ships. The results demonstrate that the permutation entropy of the intrinsic mode function with the highest energy is better in separability as the characteristic parameter than the other three parameters by comparing their fluctuation ranges and the average values of the four characteristic parameters. Hence, the feature of ship radiated noise can be extracted efficiently with the method.
Modeling of temporal groundwater level variations based on a Kalman filter adaptation algorithm with exogenous inputs
Authors: Varouchakis Emmanouil A.
Published: November 2016

Reliable temporal modelling of groundwater level is significant for efficient water resources management in hydrological basins and for the prevention of possible desertification effects. In this work we propose a stochastic method of temporal monitoring and prediction that can incorporate auxiliary information. More specifically, we model the temporal (mean annual and biannual) variation of groundwater level by means of a discrete time autoregressive exogenous variable (ARX) model. The ARX model parameters and its predictions are estimated by means of the Kalman filter adaptation algorithm (KFAA) which, to our knowledge, is applied for the first time in hydrology. KFAA is suitable for sparsely monitored basins that do not allow for an independent estimation of the ARX model parameters. We apply KFAA to time series of groundwater level values from the Mires basin in the island of Crete. In addition to precipitation measurements, we use pumping data as exogenous variables. We calibrate the ARX model based on the groundwater level for the years 1981 to 2006 and use it to predict the mean annual and biannual groundwater level for recent years (2007–2010). The predictions are validated with the available annual averages reported by the local authorities.
CAMPUS WALKABILITY IN MALAYSIAN PUBLIC UNIVERSITIES: A CASE-STUDY OF UNIVERSITI MALAYA
Authors: Keat Liow Ken , Mohd Yaacob Naziaty , Hashim Nor Rasidah
Published: November 2016

Universities are important innovation hubs for sustainable development. As universities worldwide are striving to provide conducive living and learning environments for their students and staff, the mobility of campus users is one of the challenges that have to be overcome immediately. In order to understand the issues of campus mobility, this study was conducted to evaluate a component of mobility, i.e. its walkability features and potential. The location of this study was in Universiti Malaya. We divided the study in two stages: 1. Students’ surveys to find out their perceptions on the features, potential and policy on walkability. 2. Direct observations and measurements of the existing walkability conditions (vehicular and pedestrian circulation and the street elements that constitute a walkable environment). The main findings were as follows: Most students perceived the overall walkability environment at UM did not give them a positive walking experience on campus. Street elements that are user-friendly were found to be lacking although there existed some positive ones, e.g. traffic calming devices especially at pedestrian crossing area. Although this is a case study of UM, we feel that the issues are of general interest to other university campuses, especially those located in major cities and having the same organizational structure. We would therefore recommend university management to conduct periodical campus walkability evaluation and to take the user’s perceptions seriously so as to provide better adaptation solutions to their campus sustainability projects.
Стан панкреатобіліарної системи та інтестинальної мікрофлори в дітей із неалкогольною жировою хворобою печінки
Authors: Zavgorodnya N.Yu. , Lukianenko O.Yu. , Konenko I.S.
Published: November 2016

Неалкогольна жирова хвороба печінки (НАЖХП) об’єднує такі патологічні стани, як стеатоз печінки, неалкогольний стеатогепатит, фіброз та цироз печінки, і вважається печінковим проявом метаболічного синдрому. Не лише печінка стає органом-мішенню в разі формування метаболічного синдрому: доведена можливість розвитку стеатозу жовчного міхура, підшлункової залози та біліарного тракту. Жирова інфільтрація панкреатобіліарного тракту асоційована з порушенням процесів травлення, що супроводжується розвитком дисбіотичних змін та інтестинальних розладів. Зміни кишкової мікробіоти, зі свого боку, можуть індукувати системну запальну реакцію та сприяти прогресуванню НАЖХП. Мета: вивчити структурно-функціональний стан панкреатобіліарної системи та зміни тонкокишечної мікрофлори в дітей із НАЖХП. Методи. У 34 дітей із патологією шлунково-кишкового тракту визначали контрольований параметр ультразвукового затухання із використанням апарата FibroScan. Оцінку функціонального стану біліарного тракту здійснювали за допомогою ультразвукового дослідження органів черевної порожнини із пробним сніданком для визначення скоротливої функції жовчного міхура й тонусу сфінктера Одді. Для характеристики стану тонкокишкової мікробіоти проводили водневий дихальний тест із навантаженням глюкозою або лактозою. Розподіл дітей на групи відбувався згідно з даними транзієнтної еластрографії печінки (FibroScan): контрольну групу становив 21 пацієнт без стеатозу печінки, основну групу — 13 пацієнтів із стеатозом печінки. Результати. Діти з неалкогольною жировою хворобою печінки мали ознаки ураження не тільки печінки, але й жовчовивідних шляхів та підшлункової залози. Патологія жовчовивідних шляхів у пацієнтів із НАЖХП частіше проявлялась у вигляді гіпотонії сфінктера Одді та гіпокінезії жовчного міхура. Ураження підшлункової залози в дітей із НАЖХП може пояснюватися наявністю функціонального розладу сфінктера Одді та проявами стеатозу підшлункової залози. Зміни в стані мікрофлори тонкої кишки спостерігалися у 27,6 % обстежених хворих. Синдром надмірного бактеріального росту вірогідно частіше відмічався в групі хворих зі стеатозом печінки.
Вплив функціонального стану жовчного міхура на особливості ліпідного обміну в дітей зі стеатозом печінки
Authors: Stepanov Y.M. , Zavgorodnya N.Y. , Babiy S.O. , Klenina I.A.
Published: November 2016

Мета. Вивчити особливості ліпідного обміну в дітей зі стеатозом печінки залежно від функціонального стану жовчного міхура. Матеріали і методи дослідження. Під спостереженням перебувала 31 дитина віком від 10 до 17 років. Пацієнти сформували 4 групи: І група — 8 дітей з нормокінезією жовчного міхура без стеатозу печінки, яку обрано як групу порівняння; ІІ група — 11 дітей з гіпокінезією жовчного міхура без стеатозу печінки; ІІІ група — 6 дітей з нормокінезією жовчного міхура і стеатозом печінки; IV група — 6 дітей з гіпокінезією жовчного міхура зі стеатозом печінки. Як дослідні маркери ліпідного спектру сироватки крові використано вміст загального холестерину, тригліцеридів, ліпопротеїнів високої щільності, ліпопротеїнів низької щільності, ліпопротеїнів дуже низької щільності й розраховано коефіцієнт атерогенності. Результати. Вивчено особливості ліпідного спектра крові при стеатозі печінки в дітей залежно від функціонального стану жовчного міхура. Показано, що найпоширенішими фенотипами дисліпопротеїнемій серед обстежених дітей були ізольована гіперхолестеринемія з дисліпопротеїнемією ІІа типу і комбінована гіперліпідемія з дисліпопротеїнемією ІІb типу. Виявлено, що характерною для дітей зі стеатозом і гіпокінезією жовчного міхура є дисліпідемія, яка проявляється у зростанні в сироватці крові вмісту загального холестерину, ліпопротеїнів низької щільності і коефіцієнту атерогенності. Серед пацієнтів зі стеатозом відмічався високий відсоток дітей, у яких визначено вірогідне зниження в сироватці крові вмісту холестерину ліпопротеїнів високої щільності і холестерину ліпопротеїнів дуже низької щільності, що призводило до посилення атерогенних властивостей крові при нормальному рівні всіх інших ліпідних фракцій. Наукова новизна. Висловлено припущення про існування різних шляхів формування стеатозу печінки в дітей з нормокінезією та гіпокінезією жовчного міхура, підґрунтям яких є порушення жовчоутворення й жовчовиведення. Практична значимість. Запропоновано проведення постійного контролю рівня загального холестерину, холестерину ліпопротеїнів високої щільності й холестерину ліпопротеїнів дуже низької щільності як додаткових маркерів для раннього виявлення розладів ліпідного обміну в дітей з функціональними порушеннями біліарного тракту за гіпокінетичним типом.
Досвід використання пробіотичних штамів Lactobacillus acidophilus R0052 та Lactobacillus rhamnosus R0011 у дітей з опіковою травмою
Authors: Patsera M.V. , Skrypnykova Ya.S. , Ivan’ko O.H.
Published: November 2016

На сьогодні опіки посідають друге місце серед усіх травм дітей. Основною причиною летальних наслідків у випадку виражених та глибоких опіків є інфекція, що виникає у 23–82 % усіх випадків опіків. Раціональна антибактеріальна терапія має велике значення в боротьбі з генералізованою інфекцією. Метою цього дослідження було ретельне вивчення епідеміології та характеристики антибіотик-асоційованої діареї (ААД) у хворих дітей з опіками, а також можливість запобігання цій діареї, що виникала внаслідок антибактеріальної терапії в пацієнтів Обласного опікового відділення м. Запоріжжя. Протягом 2012–2015 років ми спостерігали 438 дітей з опіковими травмами, які приймали антибіотики. У цих госпіталізованих дітей було знайдено специфічні для ААД Clostridium difficile токсини А + В у фекаліях. Це дозволило діагностувати Clostridium difficile-ентероколіт, пов’язаний з прийомом хворими антимікробних препаратів (A4.07, МКБ‑10). Розроблено профілактичні методи AAД, а саме призначення з перших годин перебування в стаціонарі per os пробіотичного засобу Lactobacillus acidophilus R0052 і Lactobacillus rhamnosus R0011 у складі препарату Lacidofil®. Використання пробіотичних штамів з антитоксичною активністю щодо Clostridium difficile скорочує в 3,4 раза число випадків антибіотик-асоційованої діареї в дітей з опіками та зменшує тяжкість її симптомів.
Weighing serological evidence of human exposure to animal influenza viruses − a literature review
Authors: Sikkema Reina Saapke , Freidl Gudrun Stephanie , de Bruin Erwin , Koopmans Marion
Published: November 2016

Assessing influenza A virus strains circulating in animals and their potential to cross the species barrier and cause human infections is important to improve human influenza surveillance and preparedness. We reviewed studies describing serological evidence of human exposure to animal influenza viruses. Comparing serological data is difficult due to a lack of standardisation in study designs and in laboratory methods used in published reports. Therefore, we designed a scoring system to assess and weigh specificity of obtained serology results in the selected articles. Many studies report reliable evidence of antibodies to swine influenza viruses among persons occupationally exposed to pigs. Most avian influenza studies target H5, H7 and H9 subtypes and most serological evidence of human exposure to avian influenza viruses is reported for these subtypes. Avian influenza studies receiving a low grade in this review often reported higher seroprevalences in humans compared with studies with a high grade. Official surveillance systems mainly focus on avian H5 and H7 viruses. Swine influenza viruses and avian subtypes other than H5 and H7 (emphasising H9) should be additionally included in official surveillance systems. Surveillance efforts should also be directed towards understudied geographical areas, such as Africa and South America.
Trespass into the Liminal
Authors: Martínez Francisco , Laviolette Patrick
Published: November 2016

This article outlines narratives of trespass. It analyses relations between the personal and the social in abandoned urban physical surroundings. Grounded in our own duo-auto-ethnographic encounters with off-limit places, the research examines the classic notion of liminality through a set of prisms that are less than orthodox. It does so by stressing the formative and transformative possibilities of those threshold spaces that often get bypassed, surpassed or trespassed. Through a series of vignettes describing moments of urban exploration in different parts of Estonia, our implicit aim is to unsettle such conceptual categories as risk and adventure, material decay and transgression. Explicitly, we argue for revisiting storytelling tropes such as the flâneur or the stalker, freeing them up from their respective leisure and pastime associations.
The (In)visibility of the Iberian Lynx
Authors: Lopes-Fernandes Margarida , Frazão-Moreira Amélia
Published: November 2016

Not much is known about how the cultural image of predators has been constructed in Western contexts and changed through time. This article reviews representations of lynx in Western Europe. A ‘cultural map’ of lynx in historical contexts is presented, and the ‘social visibility’ of the Iberian lynx in Portugal explored. Since prehistoric times the lynx has been an inspiration, an amulet, a creature gifted with extraordinary capacities but also a food item, and a ‘vermin’ to eliminate. Recently, the Iberian lynx has become a global conservation emblem; once a noxious predator, it is now a symbol of wilderness. Examples show how the species acquired visibility and has been appropriated in contemporary contexts such as logos, ‘green’ marketing, urban art or political campaigns. There is also evidence of a new identity construction in Portuguese rural areas where lynx is being reintroduced, exemplifying a process of objectification of nature.
Women and Carnival Space
Authors: Zervou Regina
Published: November 2016

This article focuses on gender relations through the performance of carnival rites in a North Aegean island rural community. Based on qualitative research, it approaches the women’s use of public space during carnival and the changes under the influence of women’s emancipation since the 1970s. The percentage of women, especially young girls, participating in carnival rites has risen dramatically over the last decade. However, not all carnival public spaces are equally open to women. The article examines the way women try to impose their presence on the strictly male universe of the carnival space and especially the marketplace, the traditional and timeless core of the carnival rites, where only men can pronounce the obscene carnival language, fruit of the kafeneion male discourse and the reactions of the male community to the novelties brought by feminism into the village.
European Bodies?
Authors: Lewicki Paweł
Published: November 2016

Drawing upon ethnographic fieldwork between 2007 and 2011 in Brussels, this article shows how visual markers, class distinctions and classification of gender performances come together to create a ‘Euroclass’ among European civil servants. These markings, distinctions and classifications are denoted on bodily hexis and body performance and evoke stereotypes and essentialised representations of
national cultures. However, after the enlargements of the EU in 2004 and 2007 they also reveal a postcolonial and imperial dynamic that perpetuates the division into ‘old’ and ‘new’ Europe and enables people from old member states to emerge as a different class that holds its cultural power firm in a dense political environment permeated
by networks.
Model-checking trace-based information flow properties for infinite-state systems
Authors: D’Souza Deepak , Raghavendra K.R.
Published: November 2016

We consider the problem of model-checking some of the well-known trace-based information flow properties from the literature for classes of infinite-state system models. We first define some language-theoretic operations that help to characterize language inclusion in terms of these properties. This gives us a reduction of the language inclusion problem for a class of system models, say [Formula: see text], to the model checking problem for [Formula: see text], whenever [Formula: see text] is effectively closed under these language-theoretic operations. We apply this result to show that the problem of model-checking any of these properties for One Counter Nets, One-Counter Automata, Basic Parallel Processes, and some properties for deterministic One Counter Automata, is undecidable. We also consider the class of Visibly Pushdown Systems and show that their model-checking problem is undecidable for a couple of properties. For the special case when all confidential events are internal we show that model-checking each of these properties for Visibly Pushdown Systems becomes decidable.