bluuebunny/crossref_metadata_2025 huggingface dataset:
On homeomorphisms of groups of automata permutations
Authors: Makarov Vladimir Vladimirovich
Published: April 2023

The author previously proved that the automaton permutation group AS2 generated by elements of infinite order. The question remains open on the generation of AS2 by elements of the second order. The article provides an example subgroup of AS2 generated by involutions containing a homomorphic prototype of the entire AS2.
Hardly describable almost polynomial classes of requrrent sequences
Authors: Makeev Sergey Danilovich
Published: April 2023

In this report, we will describe the problem of "hard to describe" classes return sequences, that is, such that the prediction behavior of such sequences is an algorithmically undecidable task. Integer classes will be considered sequences whose generating functions are composed compositions of polynomials (with integer coefficients) and some functions f. The main question under consideration is what should be this f, so that the resulting class is hard to describe. Such functions f we called border. Evidence will be presented that several wide families of functions are boundary. All this evidence stem from one "central" theorem, for proof of which Minsky machine simulations are used sequences, i.e. it is constructively proved that from the system functions "polynomials plus f" (for each of the considered f) it is possible to "build" a universal computing device.
Intersections of classes of k-valued logic preserving comparisons and differences
Authors: Meshchaninov Dmitry Germanovich
Published: April 2023

New families of classes containing all linear functions. They are formed by intersections of classes from previously known families, in particular, the classes of preservation of comparisons modulo d and preservation of d-differences, d|k.
On periodicity modulo p of numerators of convergents for √p
Authors: Sidorov Sergey Vladimirovich , Shcherbakov Pavel Andreevich
Published: April 2023

A relation is obtained between the length of the period of a continued fraction for √p and the period of the numerators of its convergents over the residue field mod p. The following theorem is proved: Let p be a prime number, l is the length of the period of the continued fraction for √p, and L is the length period of the sequence of numerators modulo p of the corresponding suitable fractions. Then 1. If p = 2, then L=l=1. 2. If p is congruent to 7 modulo 8, then L=l. 3. If p is comparable to 3 modulo 8, then L=2l. 4. If p is congruent to 1 modulo 4, then L=4l.
Algorithm maximizing precision of k-classification on representatives of k equivalence classes for applied problem of selection of command dictionary
Authors: Bernadotte Alexandra
Published: April 2023

To create a BCI device that controls movement robotic arm, it is important to minimize the classification error words-commands, while it is not so important which words will be chosen as commands for a dictionary from a set of synonyms describing the corresponding movement of the manipulator. In this article, we present algorithm, the main idea of which is to solve the maximin optimization problem k−classification at maximum the worst classification accuracy between every two sets.
Game of vertex cover of a graph
Authors: Gusev Vasily Vasilievich
Published: April 2023

The paper considers the problem of finding the significance of vertices in vertex cover of a graph based on its topology. Index computed Shapley-Shubik in a cooperative game of vertex cover for some graph classes.
Multiqidit quantum hashing
Authors: Ablaev Farid Mansurovich , Vasiliev Alexander Valerievich
Published: April 2023

In this paper, we show the possible development of the technique of quantum hashing, which brings it closer to practical implementation, namely we propose a modified version of the quantum hash function, using the structure of one-photon multidimensional quantum states in basis of the orbital angular momentum.
Number of labelled spanning forests for circulant foliation over graph
Authors: Mednykh Ilya Alexandrovich , Grunvald Lilia Alexandrovna
Published: April 2023

This report will present a new method for obtaining exact formulas for the number of marked spanning forests f(n) for an infinite family graphs Hn = Hn(G1, G2,...,Gm) obtained as a circulant foliation over graph H with m vertices and fibers G1, G2,...,Gm. Each such layer in turn, is a circulant graph with n vertices. Given the family includes generalized Petersen graphs, I-graphs, sandwiches of circulant graphs, graphs of discrete tori, etc. Obtained formulas are presented in terms of Chebyshev polynomials, which helps in establishing some of their arithmetic properties, as well as in study of their asymptotic behavior.
Comparison of encodings and optimization of parameters of SAT-solver in graph coloring problem
Authors: Svistunova Victoria Romanovna
Published: April 2023

The paper considers the problem of coloring graphs of a special type, reduction of this problem to the problem of satisfiability of Boolean formulas (SAT) and optimization of the parameters of the SAT solver, which allows solving problems of such view in less time. The problem of the existence of a proper coloring graph G in k colors is, generally speaking, NP-complete for k >= 3, and can be reduced in various ways to another well-known NP-complete problem - the problem of satisfiability of Boolean formulas in conjunctive normal form. The efficiency of the work can depend on the encoding SAT solvers (specialized programs for solving a problem feasibility). The parameters of the SAT solver Glucose were optimized using the genetic algorithm implemented in the PyDGGA package. Optimization made it possible to speed up Glucose by 3-5 times.
Problem of K-finite generation of precomplete classes of linear automata
Authors: Biryukova Veronika Andreevna
Published: April 2023

In this paper, we consider the problem of K-finitely generated for of each precomplete class of linear automata operating on Galois field consisting of two elements, and in the case finitely generated, a basis is presented. Also identified some properties of sets of linear automata. In particular, this sequence conservation property in the K-closure of a set linear automata, characterized by the preservation of this sequences, and the property of preservation at the initial moment of time Boolean functions of one essential variable in the K-closure of the set linear automata, where each automaton of this set also has this property.
On expressive abilities of ensembles of decision trees
Authors: Sokolov Andrey Pavlovich
Published: April 2023

Decision trees and their ensembles are widely used in machine learning, statistics and data analysis. Predictive models based on decision trees, show outstanding results in terms of quality and learning time. Especially on heterogeneous tabular data. Speed performance, simplicity and reliability make this family of predictive one of the most popular models in machine learning. important parameters when training ensembles of decision trees (random forest, gradient boosting, etc.) are: the number of trees and their maximum depth. These options are usually selected by a complete enumeration of all possible options on the training sample. The report will prove a theorem on expressive the possibilities of an ensemble of decision trees of limited depth. From of this result it follows that the depth of the decisive trees cannot be replaced by the size of the ensemble.
Binary trees polyhedra
Authors: Shcherbakov Oleg Sergeevich
Published: April 2023

n this paper, we study minimal fillings of finite metric spaces (an object that arose as a generalization of the concepts of the shortest tree and minimal filling in the sense of Gromov). As you know, the weight minimum filling of a given type can be found as a solution linear programming problems or using the so-called multitours. The relationship between these two approaches can be seen passing to the dual problem of linear programming: rational points of a convex polyhedron, which is constructed according to the type of filling, correspond to multitours. This work is devoted to the study of such polyhedra. It is shown that their vertices correspond to irreducible multitours. A description of the polyhedron and an explicit weight formula are obtained for the minimum parametric filling of a binary tree of type "snake".
On N-adic complexity of quaternary biquadratic sequences
Authors: Edemsky Vladimir Anatolievich , Koltsova Sofia Alekseevna
Published: April 2023

The N-adic complexity of quaternary sequences is studied, which are determined on the basis of classes of biquadratic residues by simple module. It is shown that the considered sequences have high N-adic complexity for different values of N.
On existence of A-primitive partitions
Authors: Tarannikov Yury Valerievich
Published: April 2023

It is proved that for any natural m there exists the least positive integer N=Nq(m) such that for n>N there are no A-primitive partitions Fnq into qm affine subspaces of dimension n-m. Lower and upper bounds for N=Nq(m) are obtained. The results of that of the same type are set for face tilings.
Significant serum proteinic and metabolic alterations in hepatitis B cirrhosis patients treated with umbilical cord mesenchymal stem cells
Authors: Feng Tianhang , Shang Jin , Lai Chunyou , Yao Yutong , Zhong Deyuan , Yang Qinyan , Wang Sijia , Shi Ying , Huang Xiaolun
Published: April 2023

Stem cells based-treatment is considered as an effective regenerative therapy for liver cirrhosis patients. Data about impact of stem cell transplantation on circulating metabolites in liver cirrhosis patients remains limited. In this study, eligible participants with hepatitis B cirrhosis were injected with 10E7 umbilical cord mesenchymal stem cells (uc-MSCs) through ultrasound-guided percutaneous liver puncture and portal vein catheterization. Changes of serum samples after treatment were measured by performing proteomics and metabolomics. As illustrated, proteins enriched in ECM remodeling were significantly altered, such as 20S proteasome subunits and laminin. Types of circulating phosphatidylcholine were augmented in patients after uc-MSCs treatment compared to original levels (14:0, 16:1, 18:1, 18:2, 20:1, 20:4), whereas phosphatidylethanolamine was diminished (20:4). Changes of serum profiles demonstrated that uc-MSC treatment is efficient in repairing tissue damage and metabolic disorders, revealing early biomarkers in clinical evaluation of uc-MSC treatment in liver cirrhosis patients.
Spatial spillover effect of Green Finance and Clean Energy on China's Provincial Green Economic Development
Authors: Zhang Minglong , Zheng Li , Xie Ying
Published: April 2023

Green finance is a new financing mode that pays attention to environmental benefits. Achieving a balance between the economy and the environment requires clean energy. For formulating policies to achieve sustainable development goals, it is very important to explore whether integrating green finance and clean energy is conducive to promoting green economic development (GED). This study applies a non-radial directional distance function (NDDF) to assess China's provincial GED using panel data from 2007 to 2020. It adopts the spatial Durbin model to empirically analyze the spatial spillover effects of green finance and clean energy on GED. The results indicate that: 1) The influence of green finance on GED shows a "U" curve relationship of first suppression and then rise. 2) A 1% increase in the synergy between green finance and clean energy yields a 0.1712% raise in the local GED and a 0.3482% boost to the surrounding area's GED through spatial spillovers. 3) The integration of green credit and clean energy has an apparent spatial spillover effect, and the interaction between green securities and clean energy can promote local GED. This study suggests that the government should accelerate and improve the development of a green financial market and establish a long-term linkage and co-ordination mechanism for the promotion of GED. It is crucial that financial institutions allocate more resources to clean energy development, and all regions will have to utilize the spatial spillover effect of clean energy to facilitate China's economic transformation and development in theory and practice.
Possible role of apoptosis and autophagy on mediation of tramadol induced neurodegeneration in rat hippocampus
Authors: Gholami Mina , Jamaati Hamidreza , Motaghinejad Majid , Ulloa Luis
Published: April 2023

Background
Tramadol (TRA) is a pain killer, which its abuse is widely increased during recent years, but clear mechanism for induction of neurotoxicity remains unclear. The present study aims to investigate involvement of apoptosis and autophagy signaling pathways and also mitochondrial system on TRA induced neurotoxicity.
Materials and Methods
Sixthy adult male rats were randomly divided into five groups that received standard saline and TRA in doses of 25, 50, 75, 100 and 150 mg/kg as intraperitoneal administration for 21 days, respectively. In 22th day, Open Field Test (OFT), as standard test for hippocampal cell damages was used. Also hippocampal level of JNK, Bcl-2, Beclin1 and Bax proteins as well as mitochondrial quadruple complex enzymes was measured
Results
TRA at doses 75,100 and 150 mg/kg causes dysfunction in OFT behavioral and also in mentioned high doses could increases level of both activated (total) and non-activated from of JNK and also increased Beclin-1 and Bax. TRA at doses of 75,100 and 150 mg/kg increased phosphorylated form of Bcl-2 level while decreased un-phosphorylated (total form) form of Bcl-2.
Conclusion
According to obtained data, TRA causes activation of apoptosis and or autophagy processes via modulation of TNF-α or IL-1β/JNK/Bcl-2/Beclin1 and Bcl-2/Bax signaling pathway and causes dysfunction of mitochondrial respiratory chain enzymes.
The weakening AMOC under extreme climate change
Authors: Madan Gaurav , Gjermundsen Ada , Iversen Silje Christine , LaCasce Joseph Henry
Published: April 2023

We examine changes in the Atlantic Meridional Overturning Circulation (AMOC) in the quadrupled CO2 experiments conducted under the sixth Coupled Model Intercomparison Project (CMIP6). The increase in CO2 triggers extensive Arctic warming, causing widespread melting of sea ice. The resulting freshwater spreads southward, first from the Labrador Sea and then the Nordic Seas, and proceeds southward along the eastern coast of North America. The freshwater enters the subpolar gyre north of the separated Gulf Stream, decreasing the density contrast across the current. The current weakens in response, reducing the inflow to the deepwater production regions. The AMOC cell weakens in tandem, first near the North Atlantic Current and then spreading to higher and lower latitudes. This contrasts with the common perception that freshwater caps the convection regions stifling deep water production; rather, it is the inflow to the subpolar gyre which is suppressed. Changes in surface temperature have a much weaker effect, and there are no consistent changes in local or remote wind forcing among the models. Thus an increase in freshwater discharge, primarily from the Labrador Sea, is the precursor to AMOC weakening in these simulations.
A field-enhancement optical fiber SPR sensor using graphene, molybdenum disulfide, and zinc oxide
Authors: Carvalho Igor , Xavier Renata , Fim Fabiana , Moreira Cleumar , Cruz Rossana
Published: April 2023

Graphene, molybdenum disulfide (MoS2), and zinc oxide (ZnO) are proposed here to enhance the evanescent field of an optical fiber Surface Plasmon Resonance (SPR) sensor. Gold and silver are the plasmonic materials and the fiber core material is polymethylmethacrylate (PMMA). A Fresnel equations-based analysis is used, and the obtained results pointed out higher values of sensitivity, figure of merit, and FWHM (Full-Width at Half Maximum) when compared to conventional SPR sensors. In despite of silver-only based SPR sensor has a better performance, oxidation occurs, and the sensor's lifetime is reduced. The addition of graphene layers leads to sensitivity values 50% higher than the conventional sensor. On the other hand, the MoS2-based sensor improves the interaction of the sensor with the bio-recognition molecules, which is attractive for biomedical applications. When ZnO was added to the silver-based sensor a highest sensitivity, 4,740.9 nm/RIU, was obtained. Graphene-based silver SPR exhibit the highest FOM values.
The value of serum D-dimer and tumor markers in predicting venous thromboembolism in elderly patients with stage III-IV lung adenocarcinoma
Authors: Wang Yunfei , Wu Jizhen , Huang Gairong , Wang Fei
Published: April 2023

Objective To investigate the predictive value of serum D-dimer levels combined with tumor markers for venous thromboembolism (VTE) in elderly patients with stage III-IV lung adenocarcinomas. Methods A retrospective analysis was conducted involving elderly patients with inoperable stage III-IV lung adenocarcinoma admitted to the Department of Geriatrics and Department of Respiratory and Critical Care Medicine at Henan Provincial People's Hospital between January 2019 and January 2021. Patients were divided into VTE (n = 129) and non-VTE groups (n = 192). Serum D-dimer, carcinoembryonic antigen (CEA), lung cancer antigen (CYFRA21-1), carbohydrate antigen 125 (CA-125), carbohydrate antigen 199 (CA19-9), and neuron-specific enolase (NSE) levels were compared between the two groups. The risk factors for serum D-dimer and tumor markers in elderly patients with stage III-IV lung adenocarcinoma complicated by VTE were analyzed using binary logistic regression. The ROC curve was used to evaluate the predictive value of serum D-dimer and tumor markers in elderly patients with stage III-IV lung adenocarcinoma complicated by VTE. Results Compared to the non-VTE group, the serum D-dimer, CEA, CYFRA21-1, CA-125, and CA19-9 levels in elderly patients with stage III-IV lung adenocarcinoma and VTE were significantly different (P < 0.05). Further logistic regression analysis showed that D-dimer, CEA, and CYFRA21-1 levels were risk factors for VTE in elderly patients with stage III-IV lung adenocarcinoma. The area under the curve (AUC) of D-dimer, CEA, and CYFRA21-1 levels for the prediction of stage III-IV lung adenocarcinoma combined with VTE in the elderly were 0.839, 0.720, and 0.676, respectively (P < 0.05).The predicted AUC of D-dimer combined with CEA for stage III-IV lung adenocarcinoma complicated with VTE in elderly patients was 0.861, sensitivity was 0.868, specificity was 0.671, and cut-off value was 0.771. Conclusion: Serum D-dimer levels combined with the tumor marker CEA can improve the clinical diagnosis of VTE in elderly patients with stage III-IV lung adenocarcinoma.
Thermal loads in two different urban quarters – perspectives from mobile measurements and mental maps
Authors: Moderow Uta , Ziemann Astrid , Goldberg Valeri , Sinning Heidi
Published: April 2023

The fact that different urban structures have different climatic effects and therefore differ in their thermal loads for people is well known. However, there is a lack of quantitative and qualitative surveys in specific districts that are suitable to derive accepted adaptation measures. This paper addresses the research questions where thermally stressed areas in public space are identified by mobile measurements and by mental maps and what are the causes of each, where both methods agree or disagree, and what are the benefits and the limitations of using both methods for prioritizing adaptation measures.
Mobile measurements in an urban quarter over a whole day can supply needed data for determining thermal loads of urban structures and their temporal development. Mental maps give information about the perception of urban dwellers and - based on the spatial distribution of obtained data - the user frequency. Both methods provide information concerning where and when measures should be taken in order to facilitate adaptation to heat.
The paper presents the results of mobile measurements and mental maps of two different urban quarters in Germany. Thermal loads were assessed by using the Universal Thermal Climate Index (UTCI) for three selected summer days. Results indicated that the different urban structures can differ by up to 7 K or by two stages of thermal stress during a hot summer day. Surface material with high albedo can overcompensate smaller sky view factors resulting in high thermal loads. Street trees caused changing thermal loads but reduced them on average.
Identified hot spots based on mobile measurements mostly correlated with hot spots identified by mental maps, if they were frequently used. However, hottest spots identified by measurements were not necessarily most frequently named as hot spots in the mental maps. Most often named hot spots of mental maps coincided with major traffic routes suggesting that user frequency is important. We conclude that the combination of both methods can be valuable for identifying locations with high priority for climate adaptation in cities.
Do income levels and institutional quality mediate the impact of foreign direct investment on growth?
Authors: Gattini Luca , Baiashvili Tamar
Published: April 2023

We investigate the role played by country income levels and the quality of the institutional environment in mediating the impact of FDI on growth in 111 countries, stretching from developing and emerging market to advanced economies. We find that FDI benefits do not accrue evenly across country income groups. The effect is larger for middle-income countries while we detect mixed evidence for high- and low- income countries. We make use of this first association to characterise the impact of FDI mediated by the institutional quality of countries. We uncover that institutional factors have a mediating positive effect on FDI within country income groups, whereby countries with better-developed institutions relative to their income group peers benefit more from a positive impact of FDI on growth. From a policy perspective, FDI appears a useful tool to support growth even more so when combined with a genuine reform agenda.
JEL classification: C33, F21, E02, O43, O47
Acoustic source localization through the data fusion with multi-distributed microphone arrays
Authors: Kan Yue , Ya-Peng Hu , Fu-sheng Zha
Published: April 2023

Compared with the acoustic source localization based on single array, the multi-microphone arrays have the higher robustness and accuracy in complex environment. However, it is still one of the challenges to obtain an optimal result by fusing multiple groups of the position information from multiple sub-arrays. To solve this problem, this paper introduced the Brayden Fletcher Goldfarb Shanno (BFGS) method into the localization method based on multi-microphone arrays. The BFGS method is used to an optimal objective function, which is related to the direction of the acoustic source. In addition, several initial value selection schemes of BFGS method are proposed and compared to select a best initial value. The experiments were carried out on the self-developed platform with four four-element sub-microphone arrays.
Identification and apportionment of groundwater nitrate sources in Chakari Plain (Afghanistan)
Authors: Zaryab Abdulhalim , Farahmand Assadullah , Mack Thomas J.
Published: April 2023

The Chakari alluvial aquifer is the primary source of water for human, animal, and irrigation application. In this study, the geochemistry of major ions and stable isotope ratios (δ2H-H2O, δ18O-H2O, δ15N-NO3̄, and δ18O-NO3̄) of groundwater and river water samples from the Chakari Plain were analyzed to better understand characteristics of nitrate. Herein, we employed nitrate isotopic ratios and BSIMM modeling to quantify the proportional contributions of major sources of nitrate pollution in the Chakari Plain. The cross-plot diagram of δ15N-NO3̄ against δ18O-NO3̄ suggests that manure and sewage are the main source of nitrate in the plain. Nitrification is the primary biogeochemical process, whereas denitrification did not have a significant influence on biogeochemical nitrogen dynamics in the plain. The results of this study revealed that the natural attenuation of nitrate in groundwater of Chakari aquifer is negligible. The BSIMM results indicate that nitrate originated mainly from sewage and manure (S&M, 75‰), followed by soil nitrogen (SN, 13‰), and chemical fertilizers (CF, 9.5‰). Large uncertainties were shown in the UI90 values for S&M (0.6) and SN (0.47), whereas moderate uncertainty was exhibited in the UI90 value for CF (0.29). The findings provide useful insights for decision makers to verify groundwater pollution and develop a sustainable groundwater management strategy.
End-of-production Ultraviolet A and Blue Light Similarly Increase Lettuce Coloration and Phytochemical Concentrations
Authors: Kelly Nathan , Runkle Erik S.
Published: April 2023

Anthocyanins are a group of human-health-promoting phenolic compounds that influence the pigmentation of red-leaf lettuce (Lactuca sativa). Ultraviolet A (UVA; 315–399 nm) and blue (B; 400–499 nm) light can increase the concentrations of phenolic compounds but also suppress cellular expansion, which can limit harvestable biomass accumulation. It is not known whether UVA or B light is more effective at increasing phenolic compound concentrations when they are each applied at the same photon flux density. Our objective was to evaluate the efficacy of UVA and B light when added during the end of production (EOP) at promoting phenolic compound synthesis and red-leaf coloration without limiting biomass accumulation. We grew red-leaf lettuce ‘Rouxai’ in a controlled indoor environment at an air temperature of 22 °C under warm-white and red light-emitting diodes (LEDs). On day 24, 30 or 60 µmol·m−2·s−1 from UVA, B, UVA plus B, or red plus green LEDs was added during the last 6 days of the 30-day production period. UVA and B light, alone or combined, similarly increased leaf redness (by up to 72%), total phenolic concentration (by up to 92%), total anthocyanin concentration (by up to 2.7-fold), and relative chlorophyll concentration (by up to 20%) and did not inhibit growth, compared with lettuce grown without EOP supplemental lighting. Considering B light was as effective as UVA light at increasing leaf color and phytonutrient density and that B LEDs are more electrically effective, economical, and durable, an enriched blue-light spectrum at the EOP is a comparatively sustainable method to increase crop quality without suppressing biomass accumulation.
Assessment of Factors Affecting Food Security in Tribal Community
Authors: Pooja Ambati , Rajeswari M. , Lakshmi V.
Published: April 2023

Food security means ensuring food that is available, accessible, and affordable to all the people at all times. Food security is of global concern affecting most of the people in the society at some point of time. In comparison to other population groupings, tribal communities are more vulnerable groups and face socioeconomic disadvantages and food insecurity and are “at risk” of undernutrition. This is mainly due to lack of knowledge, geographical isolation, and suboptimal utilization of health services. Objectives of this study are to determine sociodemographic profile of tribal community, to assess nutritional status, to assess and evaluate the availability, accessibility of various foods, and factors influencing food security in tribal communities. It was a community-based study carried out by random sampling procedure in different villages of Paderu division, Alluri District, Andhra Pradesh by taking permission from the Integrated Tribal Development Agency Project Officer and Administrative Officer for conducting the study. Consent was obtained from the heads of the concerned households and data were collected from the participants who were willing to participate in the study. Information on sociodemographic details, anthropometric measurements, availability of various food items, severity of food insecurity, and factors affecting food insecurity were assessed using pretested schedule which included health and lifestyle related Knowledge, Attitude, and Practices (KAP). The mean body mass index was 21.6 ± 3.3 kg/m2, in which most of the men are normal, whereas women are undernourished. The KAP survey revealed that subjects possessed knowledge and attitude on health and hygiene to some extent but poorly practiced. Food insecurity experience scale revealed that the people were facing moderate to severe food insecurity. This study concludes widespread food insecurity among tribal population and there is need for proper implementation of various programs and schemes to prevent food insecurity and its consequences.
Integrative Outlook for Bahihiprakoshthi Asthibhaghna W. S. R. to Smith’s Fracture: A Case Study
Authors: Kumar Jitendra , Patil Atul , Babar Sanjay C. , Shinde Archana Kukade
Published: April 2023

Ayurveda is not only a system of medicine in the conventional sense of curing disease. It is also a way of life that teaches us how to maintain and protect mental and physical health and achieve longevity. Prevention is better than cure it is the main aim of Ayurveda. Ayurveda has many unique and important concepts are mentioned. In which the basic eight branches, that is, Ashtanga Ayurveda which includes Shalya Tantra which includes Yantra, Shastra all details regarding Shalya Chikitsa, nowadays, which is related with the Surgery in modern science. There are various unique concepts are described in the Shalya Chikitsa of Ayurveda. In which Bhagna or Asthibhagna is one of the concept. It’s Nidana, Chikitsa its prevention all are well explained in the Ayurveda science. Asthibhagna is correlated with the Fracture in the modern science. This article emphasize case study of Asthibhagna, treated with Ayurvedic principles in particular Shodhan Chikitsa,the therapy which expels out pathological Doshas from the body. Shodhan Chikitsa helps in eliminate the disease from its root level, that avoid its recurrence in future. Here is a case study of 52 year adult male patient visited in OPD of Shalya tantra presenting with complaints of Vam Hasta Shoola [Left hand pain]. Vam Hasta Alpa Shotha [Left hand mild swelling] and Sparshaasahatva [Local tenderness] since from 3 to 5 days. The patient was admitted and managed by Shodhana (Purification) along with Shamana (Pacification) Chikitsa. Kushabandha (Splint) was administered for immobilization for a duration of 60 days. Shital Kashaya aushadhis and Chakra Taila mainly for Parisheka (Irrigation). The results with marbles have been exquisite in this article.
Readiness for Practice among Pregraduate Nursing Students in South India: A Cross-sectional Survey
Authors: Suganandam Dinesh Kumar , Ravindran Vinitha , Sadan Vathsala , Priyadarsini Ida Sweetlin
Published: April 2023

Background: Often the transition from student nurse to a graduate nurse causes stress and fatigue among novice nurses. This study intended to identify the readiness for practice among pregraduate nurses. Methods: A cross-sectional online survey conducted among 195 pregraduate nursing students. Participants filled Modified Casey-Fink Readiness for practice tool. A total of 192 students responded to the survey. Student t-test and ANOVA were used to identify the difference in practice based on demographic variables. Results: Overall mean score of readiness for practice among pregraduate nurses was found to be 58.5 ± 5.58. There was significant difference in readiness for practice in terms of their religion and program of study. Conclusion: To facilitate the smooth transition from student to professional, a planned preparatory program may be useful at the course completion.
Identification of Novel Coixol-Based Derivatives as the Potential Anti-diabetic Agents Through Molecular Docking Studies
Authors: Patle Deepshikha , Kaur Paranjeet , Khurana Navneet
Published: April 2023

Objective: The objective of this study was to design and identify the novel promising anti-diabetic agents based on the naturally existing potent insulin secretagogue coixol that can improve the potency overcome the adverse effects of existing medicines. Methods: The Auto Dock Vina (ADT) 1.5.6 and PyMOL software were used for molecular docking and visualization purposes. The molecular structures were drawn in Chem Draw 16.0 and by the help of Chem Bio draw three dimensions, all structures were energy minimized by MM2 method and converted to PDB extension file which is readable at the ADT interface. Result: Total 254 designed molecules from each series 1–4 were checked for binding score with the receptor 5yw7. Out of that total 12 molecules from each series were selected on the basis of their binding affinity in each series. Among these coixol (Natural product), DP322, DP330, and DP422 were studied in-depth. Conclusion: Coixol-based derivatives which scored best binding affinity such as DP332, DP330, and DP422 were shown promising result on the interaction with the K+ ATP sensitive Potassium channel protein (5yw7). The entire study suggests that these novel coixol-based derived molecules could be a promising lead for the further discovery and investigation of insulin sensitizing agents for the treatment of diabetes.
Comparison of Arthroscopy and Arthrocentesis in the Management of Internal Derangement in TMJ Disorders: A Systematic Review
Authors: Dubey Prajesh , Mowar Apoorva , Sharma Shelly , Vashisht Sahil , Gupta Nitish , Panwar Shreya
Published: April 2023

The aim of the systematic review is to shed some light on comparison of Arthroscopy and arthrocentesis in the management of internal derangement in temporomandibular joint (TMJ) disorders. A comprehensive electronic search was conducted with no date or language constraints. Human research, such as randomized or quasi-randomized controlled trials, controlled clinical trials, and retrospective studies comparing arthrocentesis and arthroscopy in the treatment of internal derangements in TMJ disorders, was included in this study. After considering the exclusion and inclusion criteria, seven studies were being included in the systematic review. Because all trials employed the same scale, the weighted mean difference (WMD) was used to compute the Maximum inter-incisal opening (MIO) (in millimeters) and pain in the continuous data (by visual analog scale). The improvement in MIO following arthroscopy was greater than that following arthrocentesis. The difference in pain reduction between arthroscopy and arthrocentesis patients was statistically significant (fixed: WMD = 0.42, 95% CI: 0.54–0.30; P = 0.00001). When compared to arthrocentesis, arthroscopy lysis and lavage were shown to be more effective in improving MIO and lowering pain.
A Study on Status of Mental Health among Male and Female Senior Secondary Level Students of Uttarakhand State
Authors: Ansari Azhar Hussain , Yadav Hiralal , Pant Mukul
Published: April 2023

Mental health of the student has been a big concern for parents in the academic world in recent times. The outbreak of the COVID-19 pandemic made huge contributions in it by forcing the school to adopt online teaching and subsequently confining the young generation to their homes and endless hours of screen time. Although online teaching has made academic activities possible at least during this pandemic situation, it has also caused significant stress on the mental health of school children. The present study has been conducted to find out the status of mental health among male and female senior secondary level students of Uttarakhand state. Total of four hundred (400) Senior secondary level Male and female students studying in different schools and Boards of Uttarakhand State were selected as subjects by using random sampling method. The subjects were Aged between 14-19 years and were studying in 9th-12th classes at different schools in Uttarakhand state. Mental Health Status was assessed using the Mental Health Scale developed by Dr. Shushma Talesara and Dr. Akhtar Banao [2017]. The collected data were analysed using mean, standard deviation, and independent t-test. The level of significance was fixed at 0.05. The result revealed that there was a significant difference in the total mental health status between male and female students. Female students were better on mental health status than male students. In subcategories of mental health status, there was a significant difference found for home-related causes, whereas, in the other two subcategories, there was no significant difference between male and female students of Uttarakhand state.
Users’ Intention to Use Mobile Health Applications for Personal Health Tracking
Authors: Chrisdianti Galuh Octavia , Handayani Putu Wuri , Azzahro Fatimah , Yudhoatmojo Satrio Baskoro
Published: April 2023

This study aimed to analyze factors influencing the intention to use mobile health applications for personal health tracking (PHT). The respondents were 516 individuals who had used a PHT application, such as Samsung Health, iOS Health, or MiFit. Data processing was done via using partial least squares–structural equation modeling (PLS-SEM). This study uncovered factors that can affect intention to use PHT applications, including perceived usefulness, social influence, facilitating conditions, hedonic motivation, habits, performance risk, and self-health awareness. It was found that perceived ease of use and self-reported health condition do not affect the intention to use PHT applications. This study can provide guidance on PHT application service providers for ensuring data accuracy, increasing user satisfaction when using the applications, and preventing privacy violation.
Acceptance Analysis of The Electronic Kohort Information System for Maternal and Child Health (MCH) Using the Technology Acceptance Model (TAM) Method at the Bima City Health Centers
Authors: Hizriansyah
Published: April 2023

The Maternal and Child Health (MCH) Program in Indonesia is faced with a diversity of achievements between regions caused by disparities in the capacity of the health system and exacerbated by the Covid-19 pandemic which has caused a decrease in service activities and reporting quality so that digitalization of services is needed.  This type of research is qualitative research with the design of phenomenological studies using thematic analysis with the help of the Nvivo 12 application. Primary data collection was carried out by means of observation and in-depth interviews with research informants by purposive sampling. To increase the credibility of the data use source triangulation. The research informants consisted of the head of the family health services section, the head of the health centers and the midwife as the user of the e-cohort.  Thirteen informants (11 women and 2 men) participated in the study. Most informants can use the core functions of the e-cohort app navigation menu. The study proposes that the perceived perception of ease of use may not be in line with the perceived expediency of explaining variations in the successful acceptance of MCH e-cohort applications. The study also found that there were differences in outcomes between user perceptions at the operational level and policy makers at the managerial level. In general, the analysis collects several types of obstacles and potentially problems that negatively affect the usefulness of the e-cohort application : not being able to make the work of midwives easier and faster, ineffective and not so much to increase the productivity of performance. With regard to ease of use, users feel that the e-cohort can be easily learned and used.  The e-cohort is considered to have value as a system that makes the work of midwives more difficult and hinders the work, however, the appearance, elements, features and design are perceived to be quite easy to use. In addition, users also highlight the need to consider how the system can be implemented in order to minimize the impact and optimize usability
O emprego de cremes como auxiliares no preparo do canal radicular: Estágio atual
Authors: Gilson Blitzkow SYDNEY  , Denise Piotto LEONARDI  , Antonio BATISTA
Published: April 2023

Os autores deste artigo fazem uma revisão da literatura sobre o emprego decremes como substâncias químicas auxiliares da instrumentação, que forammuito utilizados nas décadas de 1970 e 1980. Com o entendimento daimportância da remoção do magma dentinário previamente à medicaçãointracanal e obturação, e com a confirmação de que o uso de cremes propiciavauma maior quantidade de magma nas paredes do canal radicular, seu uso foiquase abandonado nos anos 90. Entretanto, nesse período, algunspesquisadores descobriram como removê-lo, de modo que os cremes voltarama ser enfatizados. Com o advento das peças automatizadas, principalmenteaquelas de rotação contínua com instrumentos de níquel-titânio, os quaispossuem menor capacidade de corte e são empregados com rotação em tornode 250 rpm, os fabricantes começaram a recomendar os cremes em virtude dasua propriedade de lubrificação, pois facilitam o trabalho do instrumento.Como a formação de magma dentinário é maior com peças automatizadas e oemprego de solução de EDTA propicia paredes livres de sua presença, estudosprecisam ser desenvolvidos no sentido de determinar sua real efetividade contraas bactérias anaeróbias presentes nos dentes portadores de lesão periapical.
Comparison of the Efficacy and Safety of Ultrasound-Guided Sclerotherapy
versus Cystectomy for the Treatment of Ovarian Endometriomas: A Systematic
Review and Meta-Analysis
Authors: He You , Wang Dan , Deng Youlin
Published: April 2023

Background:

Ultrasound-guided sclerosis has been used to treat ovarian endometriotic
cysts since 1988. However, compared with cystectomy, sclerotherapy's effectiveness and safety are
questionable.

Objective:

To compare ultrasound-guided sclerotherapy and ovarian cystectomy in the treatment of
ovarian endometriosis through a systematic review and meta-analysis.

Methods:

PubMed-MEDLINE, EMBASE, Cochrane, and Scopus databases were searched, and related literature was collected. The two treatments' recurrence rate, pain relief rate, pregnancy rate, technical success rate, and complication rate were directly compared.

Results:

Six studies (386 patients) were included. The risk of recurrence with sclerotherapy was higher
than that with cystectomy (OR 1.57, p = 0.52). Subgroup analysis showed that an indwelling time >
10 min was not significantly different regarding recurrence risk between sclerotherapy and cystectomy
(OR 1.01, p = 0.99). When the indwelling time was ≤ 10 min, the risk of recurrence with sclerotherapy
was significantly higher than that with cystectomy (OR 22.01, p = 0.001). The pregnancy rate after
cystectomy was lower than that after sclerosis (OR 1.67, p = 0.22). Complications in the study were
graded according to the Clavien‒Dindo classification and statistical analysis showed that the probability
of serious complications (Grade III-V) with cystectomy was higher than that with sclerosis
(16.67% vs. 0%).

Conclusion:

Ultrasound-guided sclerotherapy was not inferior to cystectomy in terms of recurrence
rate or pregnancy rate, and the incidence of severe complications was lower than that in the cystectomy group. Sclerotherapy is a safe and effective alternative treatment for ovarian endometriosis.
Feasibility Study of Combining Wall Shear Stress and Elastography to Assess
the Vascular Status of Carotid Artery
Authors: Gao Wenjing , Dong Yinghui , Hong Shaofu , Song Di , Liu Mengmeng , Wei Zhanghong , Du Yigang , Li Shuangshuang , Xu Jinfeng , Dong Fajin
Published: April 2023

Introduction:

At present, early detection of the potential risk of atherosclerosis and prevention is of great significance to reduce the occurrence of stroke.

Aim:

This study aims to explore the value of combining the wall shear stress measured by ultrasound vector flow imaging technique and sound touch
elastography of common carotid artery in normal adults using the Mindray Resona 7 ultrasound system.

Methods:

Forty volunteers (mean age 39.5 y, 23 females, 17 males) were divided into four groups according to their age. All volunteers underwent
ultrasound carotid artery examination, and the values of wall shear stress and elasticity on the posterior wall of the common carotid artery were
measured using advanced imaging functions, vector flow imaging technique, and sound touch elastography.

Results:

Different cut-off values of wall shear stress were used to investigate the significance between two groups with corresponding sound touch
elastography values. It can be seen that the statistical difference could be found when the mean wall shear stress was larger than 1.5 Pa
approximately (statistical significance was defined when P < 0.05), and the sound touch elastography value was positively correlated with the wall
shear stress value.

Conclusion:

This study reveals that the combination of wall shear stress and sound touch elastography is an effective and feasible method for assessing carotid
artery health. When the mean wall shear stress value is over 1.5 Pa, the corresponding sound touch elastography value increases significantly. The
risk of atherosclerosis increases with the stiffness of blood vessel walls.
Multisite Percutaneous Bone Augmentation for the Treatment of Acetabular
Osteolytic Metastases Involving the Articular Surfaces: A Randomised Trial
Authors: Ge Weiming , Liu Xunwei , Liu Mingzhen , Zhuo Wenkun
Published: April 2023

Introduction:

For patients with acetabular osteolytic metastases involving the articular surfaces, current treatments cannot efficiently rebuild the acetabular bone frame structure and strengthen bone defect area mechanics for weight-bearing. The purpose of this study is to show the operational procedure and clinical outcomes of multisite percutaneous bone augmentation (PBA) for the treatment of incidental acetabular osteolytic metastases involving the articular surfaces.

Methods:

According to the inclusion and exclusion criteria, 8 patients (4 males and 4 females) were included in this study. Multisite (3 or 4 sites) PBA was successfully performed in all patients. The pain and function evaluation and imaging observation were examined by VAS and Harris hip joint function scores at the different time points (pre-procedure, 7 days, one month, last follow-up in 5-20 months).

Results:

There were significant differences (p<0.05) in VAS and Harris scores before and after the surgical procedure. Moreover, these two scores had no obvious changes during the follow-up process (7 days after the procedure, one month after the procedure, and the last follow-up) after the procedure.

Conclusion:

The proposed multisite PBA is an effective and safe procedure for the treatment of acetabular osteolytic metastases involving the articular surfaces.
Comparative Evaluation of Methods for Estimation of Soil Salinity
Authors: KUMAR P , SARANGI A , SINGH D K
Published: April 2023

Different methods to estimate electrical conductivity (EC) of saturated soil paste extract (ECe) of 1:2 and 1:5 soil: water suspensions were evaluated. Soil samples were taken from different depths (viz. 0-15, 15-30, 30-45, 45-60, and 60-90 cm) of the wheat field under irrigated saline regimes ranging from 1.5 to 12 dSm-1. The relationship between the electrical conductivity of saturated paste extract (ECe) and soil-water suspension extracts (i.e., EC1:2 and EC1:5) was established beside the development of regression models and conversion factors. Regression models relating ECe with EC1:2, EC1:5 were developed with coefficients of determination (R2) 0.98 and 0.99 respectively. The average conversion factor between ECe~ EC1:2 and ECe~ EC1:5  were 2.7 and 7.7, respectively. Methods standardized in the study can be used to estimate the EC of different saturated soil paste extract ratios, which will be less cumbersome and significantly reduce the estimation time.