bluuebunny/crossref_metadata_2025 huggingface dataset:
DISKURSUS WACANA SAINS DAN TEKNOLOGI SERTA DAMPAKNYA PADA PENDIDIKAN ISLAM
Authors: Asbar Andi Muhammad
Published: March 2021

Wacana sains dan teknologi selalu menjadi diskursus jika diperhadapkan dengan Islam.Bahkan, kalangan sarjana berusaha mengintegrasikan dengan berbagai macam rupa. Pada kenyataannya dalam perkembangan Islam tercatat beberapa ilmuan Muslim.Salah satusumbangan terbesar Islam bagi dunia modernsaat ini,adalahmewariskan sejumlahteori pengetahuan tentang alam semesta dan cara-cara menerapkan pengetahuan tentangnya.Dalam banyakhal, hubungan antara ilmu pengetahuan (sains) dengan cara-cara menerapkannya (teknologi) telah banyak dicontohkan dan diuji cobakan oleh sejumlah sarjana muslim pada sekitar abad ke-9 M sampai13 M. Di sisi lain, integrasi Islam dengan sains dan teknologi juga menjadi wacana populer dan menjadi pemantik lahirnya kajian tentang hal tersebut di dunia akademik. Sehingga menghasilkan perjumpaan teori di antara keduanyayang pada akhirnya dapat disepakati semuanya bisa saling melengkapi dan tidak terpisahkan.Hakikat pendayagunaan teknologi adalah sebagai media pendukung aktivitas manusia. Hal tersebut harus disadari masyarakat sebagai dampak positif dari teknologi yang bersifat komplementer, serta dampaknya terhadap pendidikan Islam, maka harus mampu melahirkan manusia untuk mencapai kesuksesan di dunia dan akhirat sebagai tujuan utama pendidikan Islam. Inilah kausa-finalisnya mengapa dan untuk apa pendidikan Islam itu dalam pergolakan sosial, utamanya dalam era perkembangan IPTEK ini.Dengan kata lain pendidikan Islam harus ikut memainkan peran dan tidak sekedar menjadi penonton.Oleh karena itu, tepatlah bila pelajaran tentang IPTEK dimasukkan dalam pendidikan Islam, dan mutunya harus ditingkatkan.
TINJAUAN FONOLOGIS TERHADAP INTEGRASI PENGGUNAAN NAMA DIRI BAHASA ARAB DI INDONESIA
Authors: Jihada Ilfiana Iffah
Published: March 2021

Masyarakat Indonesia lebih banyak memeluk agama Islam, sehingga banyak nama diri dari masyarakat Indonesia yang menggunakan bahasa Arab. Nama diri dalam bahasa Arab di Indonesia banyak terjadi perubahan sistem kebahasaan, baik dalam sistem fonologi. Analisis nama diri berbahasa Arab dalam tataran fonologi menggunakan metode deskriptif kualitatif, di mana penulis mendeskripsikan lalu menganalisis nama-nama diri tersebut dilihat dari tataran fonologi. Sebagai contoh nama diri berbahasa Arab Jamal. Nama diri ini mengalami perubahan fonem yaitu dengan menghilangnya salah satu fonem suprasegmental yaitu tanda panjang (lenght/maddah), yang sebenarnya dalam bahasa Arab جمال dengan transliterasinya Jamaal menjadi Jamal. fenomena seperti yang disebutkan  di atas sering terjadi bahkan berulang-ulang dalam penggunaan nama diri berbahasa Arab di Indonesia, sehingga bisa diterima dan terjadilah integrasi.
PELESTARIAN LINGKUNGAN HIDUP DALAM PERSPEKTIF HADIS: STUDI ANALISIS HADITS TENTANG QADHA’ AL-HAAJAH
Authors: Muchlis Muchlis
Published: March 2021

Islam adalah agama yang mengatur bagaimana cara berinteraksi dengan Tuhan, sekaligus mengajarkan bagaimana berinteraksi dengan manusia dan lingkungannya. Petunjuk-petunjuk untuk kebaikan kehidupan manusia, sebagiannya bahkan diajarkan secara detail. Di antaranya adalah tentang aturan bagaimana seharusnya membuang hajat. Nabi Muhammad SAW lewat hadits-haditsnya mengajarkan kepada umat Islam agar ketika qadha’ al-haajah (membuang hajat) jangan sampai dilakukan ditempat-tempat yang biasa dilalui oleh manusia, di tempat berteduh, juga dibawah pohon-pohon yang buahnya biasa dimanfaatkan oleh manusia atau hewan, di air yang tergenang, di tempat pemandian (kolam renang). Petunjuk nabi agar jangan membuang hajat sembarangan selain berkaitan dengan masalah kesucian yang masuk dalam pembahasan ibadah, ternyata juga ada hikmah lain yang didapatkan seperti lingkungan menjadi terjaga dari polusi yang menyebabkan munculnya berbagai macam penyakit yang membahayakan manusia sendiri.
TINGKAT LITERASI DIGITAL MAHASISWA KEGURUAN DALAM MENGHADAPI ERA REVOLUSI INDUSTRI 4.0
Authors: Umar Umar , Hendra Hendra , Jayanti Mei Indra
Published: March 2021

Literasi digital merupakan suatu kemampuan soft skill yang selayaknya dimiliki mahasiswa guna menghadapi era revolusi industri 4.0. Sehubungan dengan hal tersebut, penelitian ini bertujuan untuk mengidentifikasi tingkat literasi digital mahasiswa keguruan dilihat dari aspek persepsi terhadap literasi digital, keterpaparan terhadap penggunaan teknologi digital, dan harapan terhadap pengembangan literasi digital. Penelitian ini merupakan penelitian lapangan (field research) yang bersifat kuantitatif. Populasi dalam penelitian ini adalah seluruh mahasiswa keguruan pada Prodi PGMI Fakultas Tarbiyah Institut Agama Islam (IAI) Muhammadiyah Bima, berjumlah 128 orang. Sampel dipilih dengan menggunakan teknik stratified random sampling  sehingga diperoleh 30 mahasiswa sebagai sampel penelitian. Hasil penelitian menunjukan bahwa tingkat literasi digital mahasiswa keguruan Prodi PGMI Fakultas Tarbiyah Institut Agama Islam (IAI) Muhammadiyah Bima dilihat dari aspek persepsi terhadap literasi digital berada pada kategori sedang (63%), aspek keterpaparan terhadap teknologi digital menempati kategori rendah (33%), dan untuk aspek harapan terhadap pengembangan literasi digital masuk pada kategori sedang (42%).
PEMIKIRAN PENDIDIKAN ISLAM: Telaah Tematik Konsep Manajemen Pendidikan Dalam Al-Qur’an
Authors: Muslim Muslim
Published: March 2021

Al-Qur’an Al-Karim mengandung mukjizat yang luar biasa baik dilihat dari segi kebahasaan, isyarat ilmiah dan pemberitaan gaib. Kemukjizatan al-Qur’an tdak dibatasi oleh ruang dan waktu serta zaman, berlaku sepanjang waktu sebagai pedoman dan petunjuk bagi umat manusia. Ajaran dan informasinya yang disampaikan al-Qur’an mencakup keseluruhan alam semesta, termasuk aspek-aspek kebutuhan manusia didunia dan diakhirat. Salah satu bagian yang tidak terlepas dari kebutuhan manusia adalah pendidikan, maka orientasi pelaksanaan pendidikan harus merujuk kepada al-Qura’an al-Karim baik dari segi konsep maupun implementasi pelaksanaannya sehingga terwujud proses pendidikan yang memiliki nilai-nilai ketuhanan dan kepribadian ynag suci. Untuk mewujudkan pelaksanaan pendidikan yang bermutu, perlu cara-cara pengelolaan yang terukur, efektif, dan efisien, sehingga akan tercapai keberhasilan pendidikan. Oleh karena itu, konsep yang menghendaki demikian perlu penerapan konsep manajemen sebagai alat pencapaian keberhasilan pendidikan.
FENOMENA MITOS YANG BERKEMBANG DI MASYARAKAT POST MODERN PERSPEKTIF ISLAM
Authors: Khosiah Nur , Muhammad Devy Habibi
Published: March 2021

Masyarakat Indonesia adalah masyarakat majemuk dari Sabang sampai Merauke memiliki kearifan lokal tersendiri yang merupakan bagian dari kebudayaan masyarakat Indonesia. Masyarakat Indonesia mempunyai kepercayaan pada hal-hal tertentu yang terkadang tidak masuk akal tetapi terjadi dalam kehidupan nyata dikarenakan kepercayaan tersebut sudah melekat dalam kehidupan masyarakat.  Hal ini yang kita sebut dengan mitos. Meskipun masyarakat sudah hidup di zaman modern dan di era digital tetapi mitos masih berkembang dalam masyarakat contoh wanita hamil jika jatuh harus merobek bajunya dan jika luka harus di obati dengan kotoran sapi (celethong),  bayi yang baru di lahirkan ketika tidur disampingnya harus tersedia sapu lidi, gunting, cermin.jika ada orang meninggal perjaka/ perawan pemakamannya harus di payungi. Dalam tulisan ini penulis akan memaparkan berbagai fenomena yang berkembang di masyarakat melalui  pengamatan dan dianalisis secara deskriptif berdasarkan perspektif Islam.
AHKAM AL-KHAMS DALAM DINAMIKA PEMIKIRAN HUKUM ISLAM DAN PERUBAHAN SOSIAL
Authors: Fuad Sahlul
Published: March 2021

Artikel ini mengajukan pendapat bahwaAhkam al-Khams sebagai acuan penilaiaan perbuatan atau tindakan dalam Islam memiliki ketahanan terhadap dinamika pemikiran hukum Islam dan perubahan sosial. Hingga saat ini hukum Islam tetap memberlakukan lima kategori untuk menilai perilaku atau tindakan para mukallaf, yang sering disebut dengan istilahAhkam al-Khams, yaitu: Wajib, Mandub, Mubah, Makruh, dan Haram. Kelima hukum tersebut menjadi acuan untuk menilai perbuatan atau tindakan (amal) para mukallaf, baik terkait hubungan dengan Tuhan (ibadah) maupun hubungan sesama manusia (muamalah). Ketetapan-ketetapan hukum tersebut pada dasarnya merupakanhasil interpretasi para ulama atas wahyu, yang yang didasarkan pada pertimbangan kriteria dan kondisi tertentu. Walaupun saat ini telah terjadi perkembangan sosial dan dinamika pemikiran hukum yang sangat pesat, namun ahkam al-khmas tetap memiliki relevansi dan tidak mengalami perubahan, kecuali pergeseran status akibat perubahan penafsiran atau pengambilan hukum atas sumber hukum.
KETELADANAN GURU DAN PENDIDIKAN DALAM KELUARGA TERHADAP KEPRIBADIAN MUSLIM SISWA DI MTs PONDOK PESANTREN AL-HUSAINY KOTA BIMA
Authors: Marliu Farizal , Surasman Otong , Taufan Taufan
Published: March 2021

Penelitian ini bertujuan untuk menentukan data empiris yang terkait dengan teladan guru dan kepribadian pendidikan siswa muslim secara terpisah atau bersama-sama. Penulis menggunakan metode survey data kuantitatif korelasional yang diperoleh dari siswa Madrasah Tsanawiyah/MTs Pondok Pesantren Al-Husainy Kota Bima, NTB. Sampel penelitian sebanyak 120 responden tahun ajaran 2017-2018.Pengumpulan data menggunakan observasi, dokumentasi, dan kuesioner.Jenis analisis ini menggunakan analisis korelasi dan regresi dijelaskan secara deskriptif. Hasil penelitian, pengaruh yang signifikan antara kepribadian guru-siswa teladan Muslim ditunjukkan oleh besarnya koefisien korelasi dan koefisien determinasi berarti bahwa setiap peningkatan satu unit skor keteladanan guru mempengaruhi peningkatan Skor Kepribadian Siswa muslim. Ada pengaruh yang signifikan antara Pendidikan dalam Keluarga dengan Kepribadian Muslim, yang berarti bahwa setiap peningkatan dalam satu unit Pendidikan dalam Skor Keluarga mempengaruhi peningkatan skor Kepribadian Muslim sebesar 0,360, itu berarti bahwa setiap peningkatan dalam satu unit nilai pendidikan dalam keluarga mempengaruhi peningkatan skor lepribadian muslim siswa. Ada pengaruh signifikan yang ditunjukkan nilai probabilitas. Nilai koefisien korelasi kedua variabel adalah 0,633 dan koefisien determinasi adalah 40,1%, yang berarti bahwa peningkatan satu unit skor dari model guru dan pendidikan di keluarga bersama-sama meningkatkan skor kepribadian siswa.
KONSEP DASAR EKONOMI ISLAM DITENGAH KONSERVATISME PEMIKIRAN EKONOMI MODERN DI INDONESIA
Authors: Bakar Abu
Published: March 2021

Konsep ekonomi Islam berbeda dan tidak mengadopsi sistim kapitalisme Barat maupun sosialisme. Sistem ekonomi Islam berbeda dari kapitalisme, sosialisme maupun negara kesejahteraan (welfare state). Walaupun disejajarkan dengan konsep sosialisme, Islam berbeda dalam hal kekuasaan negara, yang dalam sosialisme sangat kuat dan menentukan. Kebebasan perorangan yang dinilai tinggi dalam Islam jelas bertentangan dengan ajaran sosialisme. Meski demikian gagasan ekonomi kesejahteraan (welfare state) yang berada di tengah-tengah antara kapitalisme dan sosialisme memang lebih dekat ke ajaran Islam. Bedanya bahwa dalam Islam etika dijadikan pedoman perilaku ekonomi sedangkan dalam welfare state tidak demikian, karena etika welfare state adalah sekuler yang tidak mengarahkan pada “integrasi vertikal” antara aspirasi materi dan spiritual. Hal ini dapat dipahami melalui nilai-nilai dasar yang mengilhami ekonomi Islam di antara; konsep tauhid, rububiyyah, khalifah, dan tazkiyyah sebagi benyuk manifestasi nilai dasar ajaran Islam.
FILSAFAT PENDIDIKAN ISLAM: Tinjauan Antroposentris Tentang Konsep Pendidikan Manusia
Authors: Muhammad Muhammad
Published: March 2021

Kedudukan manusia dalam proses pendidikan senantiasa diperbincangkan dalam perspekstif akademik, mengingat manusia merupakan aktor utama selaku subjek dan objek pendidikan. Salah satu pokok persoalan yang selalu didiskusikan tentang manusia dalam pelaksanaan pendidikan adalah eksistensi manusia yang dapat dididik dan harus mendidik. Dalam al-Qur‟an manusia digeneralkan dengan kosa kata al-insan berasal dari kata anasa yang arinya melihat, dan banyak dijelaskan dalam al-Qur‟an. Kata insan yang bentuk jamaknya al-nas dasar kata anasa, yang berarti melihat, mengetahui dan meminta izin. Sehingga muatannya mengandung petunjuk adanya keterkaitan antara manusia dengan kemampuan penalaran, yakni manusia dapat mengambil pelajaran dari apa yang dilihatnya, ia dapat pula mengetahui apa yang benar dan apa yang salah, dan terdorong meminta izin untuk menggunakan sesuatu yang bukan miliknya. Pengertian tersebut, menunjukan adanya potensi manusia untuk dididik dan mendidik pada diri manusia. Sehingga memberikan gambaran bahwa manusia memiliki kemampuan yang tinggi untuk beradaptasi dengan perubahan yang terjadi di lingkungannya, baik perubahan sosial maupun perubahan alamiah sebagai proses pendidikan dalam diri seorang manusia.
Beyond Bizarre: Nature, Culture and the Spectacular Failure of B.F. Skinner’s Pigeon-Guided Missiles
Authors: Włodarczyk Justyna
Published: March 2021

The article uses posthumanism and animal studies as a framework for making sense of B.F. Skinner’s wartime project of training pigeons to guide missiles, with emphasis on explaining the negative response of the donors and the public. The article first considers the hypothesis that the donors’ incredulity was evoked by the species of the animal. During World War II the United States began a massive program for the training of dogs for the military, and the campaign received unanimously positive publicity in the media. Possibly, thus, dogs were perceived as capable of bravery and sacrifice while pigeons were not. However, messenger pigeons had been traditionally incorporated into the war machine and were perceived as heroic. Thus, the analysis moves on to suggest that the perception of the project as ridiculous was related to the type of behavior performed by the animals: a behavior perceived as trained (artificially acquired) and not instinctive. The analysis then shifts into how the distinction between what is perceived as instinctive (natural) and learned (artificial) behavior influences the reception of different performances involving animals. Performances built around “natural” behaviors generate much stronger positive responses, even if the naturalness of these behaviors is a carefully crafted effect.
Dream Time, Modality, and Counterfactual Imagination in Thomas Pynchon’s Mason & Dixon
Authors: Misztal Arkadiusz
Published: March 2021

This paper elucidates the structure and scope of Pynchon’s temporal imagination by studying the complex relations between narrative time and modality in his 1997 novel Mason & Dixon using the conceptual framework of contemporary narratology. It argues that Pynchon’s use of the subjunctive mode allows him not only to articulate the political and ideological concerns in his vision of America on the eve of its founding but also to address the problems of historicity, causality and irreversibility of time. By employing the subjunctive as a general narrative strategy, Mason & Dixon challenges the various temporal regimes and discourses of modernity, and projects imaginative re-figurations of time and space. In carrying this out, the novel moves beyond what Pynchon calls “the network of ordinary latitude and longitude” (Against the Day 250) and replaces a totalizing singularity with plurality of times and timescapes
Walking with the Invisible: The Politics of Border Crossing in Luis Alberto Urrea’s The Devil’s Highway: A True Story
Authors: Bańka Ewelina
Published: March 2021

The article focuses on Luis Alberto Urrea’s non-fiction book The Devil’s Highway: A True Story (2004) as a critique of the politics of border crossing and of the mechanisms of state power that shape the contemporary anti-immigration discourse. Drawing on diverse sources, the writer reconstructs the story of twenty-six Mexican men who in May 2001 attempted to cross the U.S.-Mexico border at one of its deadliest stretches – The Devil’s Highway. Documenting the story of the “undocumented,” Urrea reveals the forces that render the migrants alienated, racially stigmatized, criminalized, and dehumanized. The writer also points out that the current political debate on illegal immigration essentially pre-empts the need for a discussion that would focus on the human conditions that trigger migration rather than on the illegality of border crossing. Thus, the book reconstructs the tragic incident at the border that not only shows how the story was controlled and narrated by the entities of power but, more importantly, how it was experienced by the walkers.
Weirdness at Midnight
Authors: Welizarowicz Grzegorz
Published: March 2021

Dorothea Gail. Weird American Music: Case Studies of Underground Resistance, BarlowGirl, Jackalope, Charles Ives, and Waffle House Music. Universitätsverlag Winter, 2018, 413 pages.
Snowvision: The Promise of Algorithmic Methods in Southeastern Archaeological Research
Authors: Wilder Colin , McDorman Sam T. , Zhou Jun , King Adam , Lu Yuhang , Smith Karen Y. , Wang Song , Simmons W. Matthew J.
Published: March 2021

This article presents the contexts, methods, contributions, and preliminary findings of Snowvision, a digital archaeology project developed by faculty and students at the University of South Carolina and the South Carolina Department of Natural Resources. Snowvision uses computer vision to reconstruct southeastern Native American paddle designs from the Swift Creek period, ca. 100-850 CE. In this essay, we first present the context of the Swift Creek culture of the southeastern United States, along with broader related issues in prehistoric archaeology. Then, the relevant methods from archaeology and computer vision are introduced and discussed. We also introduce World Engraved, our public-facing digital archive of sherd designs and distributions, and explain its role in our overall project. We then explore, in some level of technical detail, the ways in which our work refines existing pattern-matching algorithms used in the field of computer vision. Finally, we discuss our accomplishments and findings to date and the possibilities for future research that Snowvision provides.
Visualizing Jonathan Edwards
Authors: Boss Robert L.
Published: March 2021

This article begins by introducing Jonathan Edwards, the eighteenth century American philosopher theologian from Northampton, Massachusetts. Edwards believed that the world of nature had communicative properties, full of types and symbols, and indeed, was a kind of language of God. This article posits that Edwards’ typological language of nature, encapsulated in his notebook “Images of Divine Things” and throughout his written corpus, can be explored through the lense of Digital Humanities and network analysis using Processing and Python programming languages. Next, the article summarizes recent Edwards-focused DH projects by Kenneth Minkema, Michał Choiński, and Michael Keller. The article then recounts the history and development of the Visual Edwards project and how it expands exploration of the 26 volume Yale letterpress edition of The Works of Jonathan Edwards. Features of the Visual Edwards software are introduced briefly, as well as print publications flowing from the project.
Voyages Through Literary Space: Mapping Globe and Nation in Richard Henry Dana’s Two Years Before the Mast
Authors: Wöll Steffen
Published: March 2021

In his youth, Richard Henry Dana Jr. rebelled against the conventions of his upper-class New England upbringing when he signed on as a common sailor on a merchant ship bound for Alta California. The notes of his travels describe the strenuous life at sea, a captain’s sadistic streak, a crew’s mutinous tendencies, and California’s multicultural fur trade economy. First published in 1840, Dana’s travelogue Two Years Before the Mast became an unofficial guide for emigrants traversing the largely unmapped far western territories in the wake of the Mexican-American War. Connecting Dana’s widely-read narrative to current developments in the discipline, this article discusses strategies of visualizing literature and includes an exercise in ‘discursively mapping’ actual and imagined spaces and mobilities of the text. Considering strategies and toolsets from the digital humanities as well as theories such as Lefebvre’s concept of representational space, the article reflects on the methodological and practical pitfalls brought about by the visualization.
A Magnificent Blond Beast: Exploring the Implications of Harlem Renaissance Writer Wallace Thurman as Ghostwriter of a Forgotten Celebrity Gossip Memoir
Authors: Frazier Peterson Whit
Published: March 2021

In an early version of his article “Harlem Literati in the Twenties,” first published in the Saturday Evening Review in 1940, Langston Hughes offers the curious suggestion that Wallace Thurman was the ghostwriter of Men, Marriage and Me (erroneously written as Men, Women and Checks in Hughes’ article), the tell-all memoir ostensibly by the original blonde bombshell Peggy Hopkins Joyce. According to Hopkins’ biographer, however, Basil Woon, an English playwright and gossip columnist was supposed to have been the ghostwriter of this book. My paper will address this discrepancy by focusing on the lack of evidence supporting the Woon theory, and through an analysis using stylometry, close reading and an examination of historical documents, I will argue that Thurman is the more likely candidate as a ghostwriter for Hopkins’ memoirs, just as Hughes suggests. I will be looking specifically at the way the text, which is presented to the reader as a diary written by Hopkins from her early youth to the present day, satirizes the shallowness and excesses of the “roaring twenties.” I will argue that the text is clearly ironic and satirical in style and approach and not only satirizes celebrity, but also a society that unselfconsciously celebrates celebrity, much the way Thurman satirizes the excesses of the Harlem Renaissance in his novel Infants of the Spring. In conclusion, I will show how this book, which has been largely dismissed as celebrity gossip, is transformed into something highly literary by the way Thurman, as ghostwriter and editor, takes Hopkins’ life story and turns it into a satire of the excesses of an era.
Impact of COVID-19 Pandemic on Management of Head and Neck Malignancy
Authors: Gupta Amit Kumar , Soni Annanya , Dubey Abhishek
Published: March 2021

With an increasing number of COVID-19 cases and a lack of definitive treatment, there is an increasing burden on already stressed health care sector in India.The patients that require medical and surgical intervention need to be triaged and provided with adequate treatment. India has a major chunk of head and neck malignancy in the world attributable to tobacco use. These patients when diagnosed early have a fair survival rate. Health personnels bear the responsibility to provide early and adequate treatment to these patients and at the same time, need to follow all measures to contain the spread of the virus. The present review highlights the various issues and newer guidelines in the management of head and neck malignancy patients during the COVID pandemic. The current review aims to present a comprehensive outlook of the updated evidence base available from PUBMED and other search engines. In India, treatment of head and neck malignancy patients are severely affected at this time of COVID-19, due to the long waiting period, delayed diagnosis, limited dedicated centres for head and neck cancer.The pandemic had diverted resources and manpower leading to potentially poor outcome of the head and neck malignancy patients. Triage policy, safety precautions for health care staff is the need of the hour and should be imbibed in regular practice.
Protocol for a Systematic Review of Mobile Phone Technology for Managing Side Effects of Chemotherapy in Cancer Patients:A Research Protocol
Authors: Praveen Uppu , Manickavasagam M , Nalini SJ
Published: March 2021

Introduction: Mobile phone technology is an evolving trend in the medical field for rendering health-related care services to the needy. Chemotherapy is one of the cancer treatments which leads to certain side effects. These side effects can be managed well with the help of mobile phones, which became an essential thing in our life in recent decades. Aim: To identify the efficacy of using mobile phone technology for managing side effects associated with chemotherapy and improvement in quality of life. Materials and Methods: A systematic review will be conducted on randomised control trials and non-randomised control trials. In this review, Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) will be followed and a literature search will be conducted in PubMed-Medline, CINHAL Cochrane Library, Scopus, Science Direct, Ovid, J-Gate, and Trip databases. The literature search for this systematic review will be done on studies published between 2007 and 2019. The quality of the study will be assessed by the JBI clinical appraisal checklist for Randomised Controlled Trials (RCTs) and Non-Randomised Controlled Trials (Non-RCTs). Studies will be included based on predetermined inclusive criteria like studies published in the English language, with keywords like cancer patients, smartphone/android applications, chemotherapy, quality of life. Results: A descriptive synthesis of the findings of the selected studies will be carried out which will be presented in a narrative summary with statistical findings incorporated. Conclusion: This review will provide up-to-date evidence to support or oppose the hypothesis that mobile phone technology plays an effective role in managing side effects associated with chemotherapy and improve the quality of life of cancer patients.
Variates and Manipulative Skills on Computer Operations of High School Students of the University of Eastern Philippines System
Authors: Galit – Cabe Honey Rose
Published: March 2021

This study aimed at examining the varieties and manipulative skills in computer operations of fourth year high school students of the University of Eastern Philippines System. A self-structured closed questionnaire with 5-point Likert scale was designed for data collection from a sample of 80 high school students and 6 teachers. This study employed the descriptive –correlational survey type of research design, Statistical tools such as frequency counts, percentages, mean, ranking and multiple regression were used to interpret and analyze the data. 

Findings revealed that the students were more skilled in terms with their manipulative skills in computer operations, more favorable attitudes while working in computer operation, and a very good academic performance showed in English, Mathematics, and Computer subjects.
Effects of Atlantic and Pacific Ocean Teleconnections on Corn Yield East of Puebla, Mexico: Case Studies
Authors: Velasco-Hernández Ma De Los Ángeles , Morales-Acoltzi Tomás , García-Castro Miguel Ángel , Bernal-morales Rogelio , Zagoya-Martínez Joaquín , Juárez-Sánchez José Pedro , Ramírez-Valverde Benito
Published: March 2021

Ocean-atmospheric interactions have effects at different scales; forming microclimates, which can explain variations with climatic or natural anomalies, between meteorological processes. This research analyzes and identifies the relationship of the teleconnection hydrometeorological effects, which determine the distribution of precipitation in corn yield. The data were used from a semi-structured interview directed to corn producers, where seven years of case studies were identified for the eastern region of the state of Puebla, Mexico. The Graphics were made with “pentad scale distribution”. The results show the importance of geographical location for agricultural activities in relation to a valley with altitudinal gradient. In addition, the corn growth cycle is associated with tropical disturbances from east Puebla region as well as Hurricane activity. It was identified that the relationship of teleconnections and the distribution of rainfall are main factors that influence in the development good or bad of corn, showed in the yields, where the different phases of ENSO (EL NIÑO Southern Oscillation) have a differentiated impact on the availability of precipitation in this case studies of the present investigation.
Adult Intussusception in a Referral Hospital in Sub-Saharan Africa: Case Report and Literature Review
Authors: Wismayer Richard
Published: March 2021

Introduction: Adult intussusception is a rare form of bowel obstruction which constitutes less than 5% of all cases of intussusception. In Sub-Saharan Africa, adult intussusception is not a rare cause of bowel obstruction. It is usually caused by a lead point which may be malignant in up to 50% of cases unlike childhood intussusceptions which are usually idiopathic. The author reports on a case of intussusception followed by a literature review on the pathogenesis and treatment options for intussusception in Sub-Saharan Africa.

Presentation of Case: A 46 year old gentleman presented with nonspecific abdominal symptoms mainly with epigastric pain associated with vomiting. No palpable masses were felt in the abdomen. Laboratory investigations were unremarkable. At laparotomy an ileo-ileal-caecal intussusception was found and when reduced 30 cm of ileum resulted gangrenous. A limited resection of the small bowel with end-to-side anastomosis involving the viable ileum and ascending colon was carried out. A lobulated lipoma was the pathological lead point on inspection of the ileum in the resected specimen.

Discussion: The atypical clinical features and pathogenesis of adult intussusception are described in the case presented. In addition, this study reviews the literature regarding the pathogensis, clinical features, diagnostic imaging modalities and treatment options of adult intussusception.

Conclusions: Patients with long standing abdominal pain and vomiting should have an abdominal CT scan to achieve a clear diagnosis of intussusception. This will avoid any unnecessary delays in the operative management of this condition.
The Influential Incidence and Prevalence of Angiohemophilia
Authors: Sultan Khalid Satam , Khaleel Asmaa Mohammed , Abdullah Salih Khudhair
Published: March 2021

Background: Angiohemophilia (VWD) is a common human inherited disease where the parent carrying the gene may or may not be symptomatic. VWD is an illness of the blood that does not coagulate correctly. Blood contains numerous proteins to stop the bleeding of the body. Von Willebrand factor VWF is one of these proteins.

Aim: Current study was planned to classify the prevalence of VWD between 2014 and 2019 in Nineveh province.

Materials and Methods: The study included 829 patients, 365 of which were carriers of one or more hemophilia factors deficiency. Special Staco kit was used for detecting VWF.

Results: Thirty out of 365 patients were diagnosed with VWD. The association between VWD and other associated variables is not significant. An acceptable value was found between age and blood type.

Conclusion: The origins of families that hold the disease mutant gene must be tracked, births taken and infection mitigation techniques used in these families established. Do not neglect the value of the sort of blood that affects the VWD directly.
Increasing Singulation Machine UPH through Characterization and Standardization of Saw and Handler Parameters through DMAIC Methodology
Authors: Rolluqui Lloyd L. , Cabading Jr Patricio A. , Domingo Jimmy P.
Published: March 2021

This study aims to address the problem of machine saturation and low capacity at package singulation, caused by increasing product loading and new devices that requires frequent machine setups and conversions.

With this evaluation, the process and equipment engineering group collaborated to improve the machine unit per hour (UPH) of package singulation machines at the manufacturing assembly.  Target improvements were divided into three phases, so that the team could focus more on each phase and was able to define robust parameters without compromising the product quality.  DMAIC methodology was used to improve the productivity of package singulation machines. With the help of our methodology, we identified the root cause and contributing factors to the problem.

UPH improvements per machine were validated and assessed in terms of machine efficiency and product quality, because of characterization and standardization of every parameter in each phase of the project. The achieved total improvement was of 17.64%.
A Comparison of Water Quality Indexes for an Inland River
Authors: Kondum F. A. , Iwar R. T. , Kon E. T.
Published: March 2021

The present study assessed water quality parameters and attempts to compare four different Water Quality Indexes (WQIs) for consistency, similarity and reliability in assessing the water quality of river Benue -an inland river- under wet and dry seasons. The results demonstrate that River Benue is continually being polluted in both dry and wet seasons by different sources, particularly domestic sewage and storm runoffs from farmlands. The quality of the water generally exceeded physiochemical and microbiological infection risk limits recommended in water quality guidelines concerning their use for domestic, recreational and irrigational purposes. Proper sewage treatment and river quality monitoring are needed to guard against hazards to public health and vulnerable river water resources. The WQIs applied were: CCME WQI, BC WQI, Dinius’ WQI and Weighted Arithmetic WQI. To evaluate the differences between these indexes, data on ten water quality parameters (Temperature, pH, total dissolved solids, electrical conductivity, Nitrates, Phosphates, biochemical oxygen demand, dissolved oxygen and faecal coliform count) for two distinct seasons from 6 river monitoring sites along the river Benue at Makurdi reach, were used. Significant discrepancies were observed in classification results between the Dinius’ WQI and the other three WQIs. Similarly, the WA and BC WQIs showed an over-optimistic rating due to their eclipsing limitation. Among others, it was concluded that any of the four indexes except Dinius’ index can be adopted but the CCME water quality index would be best suited for assessing water quality in River Benue.
Research on Meeting the Demand of the Population for a Group of Medicines Intended for the Treatment of Skin Diseases
Authors: Radzhabova Maryam  Magomedeminovna , Elgakaeva Madina Aptievna , Kostikov Andrey Petrovich , Kabanova Tatiana Alekseevna , Goncharov Vitaly V. , Subbotin Ivan Gennadievich
Published: March 2021

The problem of the spread of skin diseases in Russia and abroad in the last period is quite acute. Among the reasons for the development of this group of diseases, researchers determine genetic factors, poor ecology, impaired liver function, etc. In this regard, those suffering from this group of diseases are necessarily provided with qualified medical care, and pharmacy institutions form the necessary range of drugs that can improve the standard of living of patients. For this reason, we consider it necessary to analyze the level of demand for certain drugs used for the treatment of skin diseases in the pharmacy network of Belgorod, as well as factors that allow us to assess certain aspects that affect the formation of the range of these drugs in pharmacies.

The purpose of the work was defined as follows: to conduct a study of meeting the demand of the population for groups of medicines intended for the treatment of skin diseases. The conducted analysis shows the following. Drugs intended for the treatment of skin diseases are in high demand (59.09%); 22.73% of drugs are in low demand, the lack of demand was observed in 18.18% of the studied group of drugs.

In this paper, recommendations were formulated to optimize the assortment policy of the World of Medicines pharmacy chain in Belgorod. Since it was determined that high demand drugs such as Argosulfan, Belosalic, Avekort, Cinocap, Candiderm, Alorom, Lomaherpan, and, Nitrofungin. It is for this reason that it is necessary to increase the volume of their purchases to better meet the demand of the population for these drugs.

It was also revealed that it is necessary to reduce the volume of purchases of drugs, the demand for which is reduced. It is drugs such as Daktarin, Adolen, Camadol, Ammifurin, Bramisil, Batrafen, and Hiporhamin (they came in the results of ABC-analysis to the group C). In addition, the pharmacy should promote this group of drugs to familiarize consumers with them and offer them at a reduced price, so as not to burden the turnover of medicines and not to reduce the effectiveness of the pharmacy.

The paper concluded that, according to the study, the demand for medicines used in the treatment of skin diseases is quite high. At the same time, the administration of the pharmacy chain should pay more attention to the analysis of the purchased groups of medicines in this category in order to prevent overloading the pharmacy balance with drugs, the demand for which is reduced, as this negatively affects the effectiveness of the pharmacy organization. In this regard, it is advisable to conduct an ABC analysis of the assortment groups of drugs at least once a quarter, as well as take the necessary measures to promote drugs used in the treatment of skin diseases that are in insufficient demand among the population.
In Silco Study of MIR-124-1 Transcription Factors in Glioblastoma
Authors: Algothmi Khloud M.
Published: March 2021

MIR-124-1 is a brain-abundant MIRNA, whose expression is important for neuronal tissue division, growth and actions. However, expression of miR-124-1 regulatory mechanisms controlling its actions in neuronal cells in health and diseases still poorly addressed. To understand mechanism for transcriptional and functional regulation of miR-124 in neuronal and glioblastoma cells, this study combined gene expression profiling data and computational transcription factor and microRNA target predictions. The present research focuses on transcription factors and DNA methylation, which are central to miR-124-1 expression regulation. A core promoter sequence of miR-124-1 was predicted to be 500 bp and 100 bp, upstream and downstream of its transcription start sites. Seventy three binding sites of fifty transcription factors in promoter region were found, using MatInspector software. Among these transcription factors, MEIS1, POU3F2, SALL2, ETV1, and MAZ, are known to be brain-enriched transcriptional activators. By using omics data analysis, expression of MAZ, PLAG1 KLF2 as well as a transcriptional repressor ZNF239 showed significant correlation with decline in miR-124-1 expression in glioblastoma cells. Furthermore, a potential CpG island was reported in the promoter, providing another mechanism for transcriptional inhibition of miR-124. As miR-124-1 regulates a number of neuronal physiological and pathological processes, we made an attempt to define its potential targets. A  computational prediction of miR-124-1 targets suggested 265 targets with two or more conserved seed sites. Pathway-based analysis of these target genes revealed a significant enrichment for axonal guidance and cancer signaling pathways. At least ten of these targets, SRGAP1, GNAI3, PLXNA3, SEMA5A, SEMA6A, CEBPA, CBL, RASSF5, MITF, and RPS6KB1, showed expected inverse correlation between their expression values and miR-124-1 suppression in glioblastoma cells. Taken together, our data form foundation of subsequent future validation researches for miR-124-1 expression regulation including transcription factors and CpG Island within its promoter as well as functional regulation comprising biological pathways controlled by its target genes.
Preparation of Silymarin–quercetin Loaded Nanoparticles by Spontaneous Emulsification Solvent Diffusion Method Using D-alpha-tocopheryl Poly (Ethylene Glycol) 1000 Succinate
Authors: Senthila S. , Kumar P. Manoj , Venkatesan P.
Published: March 2021

Silymarin, a flavonolignan, derived from Silybum marianum, family Asteraceae has long been used as a hepatoprotective remedy. Silymarin has cytoprotective activities due to its antioxidant property and free radical scavenging activity. The pharmacokinetic studies of past three decades revealed that silymarin has poor absorption, rapid metabolism especially by Phase II metabolism and ultimately poor oral bioavailability. Quercetin, a flavonoid present in edible vegetables and fruits, It is a potent antioxidant and shows a wide range of biological functions. Quercetin improves blood levels and efficacy of number of drugs since it is P-Glycoprotein inhibitor and also inhibits drug metabolizing enzymes. Both silymarin and quercetin were, poorly soluble in the water shows low bioavailability. The advanced type of formulation like polymeric nanoparticles (PNPs) can be successfully utilised for bioavailability enhancement and targeting the Silymarin-quercetin to hepatocytes. A controlled release PNPs of silymarin-quercetin were prepared by spontaneous emulsification solvent diffusion (SESD) method using Poly Lactic-co-Glycolic Acid (PLGA) as biodegradable polymer, D-alpha-tocopheryl poly (ethylene glycol) 1000 succinate (TPGS) used as a solubilizer, as an emulsifier. TPGS as an emulsifier and further as a matrix material blended with PLGA was used to enhance the encapsulation efficiency and improve the drug release profile of nanoparticles. Different formulations with various drug: polymer ratios and volume and concentration of surfactant, centrifugation time were evaluated. The effect of formulation parameters such as drug/polymer ratio, volume and surfactant content were evaluated. The surface morphology and size of the nanoparticles were studied by scanning electron microscopy (SEM) Transmission electron microscopy (TEM). Drug encapsulation efficiency and in vitro drug release profiles of nanoparticles were determined using UV spectrophotometry. The nanoparticles prepared with combination of both the drugs in this study were spherical with size range of 100–200 nm. It was shown that TPGS was a good emulsifier for producing nanoparticles of hydrophobic drugs and improving the encapsulation efficiency and drug loading and drug release profile of nanoparticles. Although the amount of the TPGS used had a significant effect on the nanoparticle size and morphology, the drug loading and release profile of nanoparticles
Mg-Al/Biochar Composite with Stable Structure for Malachite Green Adsorption from Aqueous Solutions
Authors: Badri Arini Fousty , Siregar Patimah Mega Syah Bahar Nur , Palapa Neza Rahayu , Mohadi Risfidian , Mardiyanto Mardiyanto , Lesbani Aldes
Published: March 2021

Mg-Al-layered double hydroxide (LDH) was fabricated using a coprecipitation method at pH 10. Thereafter, Mg-Al-LDH was impregnated with biochar to manufacture a Mg-Al/Biochar composite. The composite was characterized using powder X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, N2 adsorption—desorption, thermogravimetry-differential thermal analysis (TG-DTA), and scanning electron microscopy (SEM) experiments, and was subsequently used for malachite green (MG) adsorption. MG adsorption experiments were performed in a batch system, and the effects of temperature and adsorption kinetic and isotherm parameters on the adsorption process were analyzed. The stability of Mg-Al/Biochar was evaluated using regeneration experiments over three cycles. The peaks at 11.47° (003), 22.86° (002), 34.69° (012), and 61.62° (116), in the XRD profile of Mg-Al/Biochar suggested that Mg-Al/Biochar was successfully fabricated. The surface area of Mg-Al/Biochar was up to five times larger than that of pristine Mg-Al-LDH. The adsorption of MG on Mg-Al/Biochar was dominated by interactions at the surface of the adsorbent and was classified as physical adsorption; moreover the maximum adsorption capacity ofMg-Al/Biochar was 70.922 mg/g. Furthermore, the MG removal of Mg-Al/Biochar during three successive adsorption cycles (i.e. 66.73%, 65.57%, and 65.77% for the first, second, and third adsorption cycle) did not change significantly, which indicated the stable structure of the adsorbent. Copyright © 2021 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Health Resource Utilization and Associated Health Care Costs of Biologic Disease‐Modifying Antirheumatic Drugs in German Patients With Psoriatic Arthritis
Authors: Sewerin Philipp , Borchert Kathrin , Meise Dominic , Schneider Matthias , Mahlich Jörg
Published: March 2021

Objective

To investigate health care costs associated with biologic disease‐modifying antirheumatic drugs (bDMARDs) in a German real‐world cohort of adult biologics‐naive patients with psoriatic arthritis (PsA).

Methods

Claims data from the Institute for Applied Health Research Berlin (InGef) research database for patients with a PsA diagnosis and bDMARD claims record (index date) between January 1, 2014, and December 31, 2017, and no bDMARD prescriptions for 365 days before the index date were retrospectively analyzed. Primary outcomes were determination of health care resource utilization and associated annual health care costs for overall and individual bDMARDs in the 12‐month pre‐index and post‐index periods. These outcomes were compared between persistent and nonpersistent groups. Nonpersistence was defined as treatment gap or switch to a bDMARD other than the index therapy.

Results

Among 10,954 patients with a PsA diagnosis, 348 were eligible. Although mean ± SD post‐index costs were significantly higher in the persistent group than the nonpersistent group (€27,869 ± 8,001 versus €21,897 ± 10,600, P < 0 .001) due to higher bDMARD acquisition costs (€23,996 ± 4,818 versus €16,427 ± 9,033, P < 0.001), persistence reduced inpatient treatment costs (–€760), outpatient treatment costs (–€192), other drug costs (–€724), and sick leave costs (–€601).

Conclusion

Although initiation of bDMARDs increased the total health care costs irrespective of persistence status, partial cost offsets were observed in the persistent patient population.
SAMHSA responds to NSDUH study
Authors: Knopf Alison
Published: March 2021

In last week's lead article on the study by Jonathan Caulkins and colleagues on the failure of the National Survey on Drug Use and Health (NSDUH) to correctly estimate the use of heroin due to that drug's low prevalence and high stigmatization (see “Study: NSDUH poor judge of heroin use,” ADAW, March 15, https://onlinelibrary.wiley.com/doi/full/10.1002/adaw.33000), a comment from the Substance Abuse and Mental Health Services Administration (SAMHSA) was not included because it arrived after press time. Here is SAMHSA's response:
Synthesis and Local Probe Gating of a Monolayer Metal‐Organic Framework
Authors: Yan Linghao , Silveira Orlando J. , Alldritt Benjamin , Krejčí Ondřej , Foster Adam S. , Liljeroth Peter
Published: March 2021

Achieving large‐area uniform 2D metal‐organic frameworks (MOFs) and controlling their electronic properties on inert surfaces is a big step toward future applications in electronic devices. Here a 2D monolayer Cu‐dicyanoanthracene MOF with long‐range order is successfully fabricated on an epitaxial graphene surface. Its structural and electronic properties are studied by low‐temperature scanning tunneling microscopy and spectroscopy complemented by density‐functional theory calculations. Access to multiple molecular charge states in the 2D MOF is demonstrated using tip‐induced local electric fields. It is expected that a similar strategy could be applied to fabricate and characterize 2D MOFs with exotic, engineered electronic states.