bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-term outcomes of laser dacryoplasty combined with intubation using a new silicon tube in patients with lacrimal duct obstruction
Authors:   Department of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China, Fan Yi-Meng , Gao Ning ,   Department of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China, Liu Zhao ,   Department of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China
Published: August 2023

AIM: To determine the 15-year outcomes of laser dacryoplasty (LDP) in patients with lacrimal duct obstruction; and to evaluate LDP combined with intubation using a new silicone tube to treat complicated cases.
METHODS: Patients with lacrimal duct obstruction and treated with LDP between April 2000 and April 2005 were investigated retrospectively. Totally 116 eyes with completed 15-year follow-up records were included in this study. For complicated cases (52 eyes of 52 patients), both LDP and intubation using a self-made silicon tube were performed. For patients with uncomplicated obstruction (64 eyes of 61 patients), only LDP was performed. Outcomes were assessed based on results of lacrimal irrigation and degree of symptoms during follow-up.
RESULTS: At the follow-up time of 15y, 81 eyes achieved full success (69.8%); 21 eyes got improved (18.1%); and 14 eyes were considered failure (12.1%). The success rate was 71.2% (37/52 eyes) for complicated cases; and 68.8% (44/64 eyes) for uncomplicated cases. No statistically significant difference between two groups was observed (P=0.961). No postoperative complication was observed.
CONCLUSION: LDP is a well-tolerated, simple, and effective procedure with satisfactory long-term outcomes in selected patients, which make it a good alternative to conventional dacryocystorhinostomy. In addition, intubation with the self-made mono-canalicular silicone tube facilitates the management of complicated cases with few complications.
Diálogos entre ficção e teoria
Authors: Brait Beth , Vera Cruz Pereira Mariana
Published: August 2023

Arte e ciência, teoria e criatividade são, sem dúvida alguma, formas do pensar e perceber o mundo, de produzir conhecimento sobre a existência, os seres, as linguagens, a vida. O diálogo entre elas, entretanto, nem sempre se dá de maneira tranquila. Considerando essa questão, assim como a teoria dialógica da linguagem, o objetivo deste artigo é apresentar e discutir a incorporação dessa perspectiva, e um de seus principais pensadores, pela ficção, pela arte. O corpus delimitado para o estudo compõe-se três enunciados, sendo um americano e dois brasileiros: Smoke, filme de Wayne Wong e Paul Auster, produzido por Greg Johnson, Peter Newman, Kenzo Horikoshi e Hisami Kuroiwa (EUA, 1995); Bakhtin: finalmente toda a verdade aparece!!!, crônica produzida por um brasileiro especialista em Bakhtin, mas atribuída a Piotr Afasinovitch Brazinov/Universidade Estatal de São Petersburgo (2012); e Hoje tem Bakhtin? Tem sim, senhor!, de autoria da professora do ensino fundamental Maria da Penha dos Santos de Assunção (2022). Eles serão analisados considerando que, ao fugir do padrão acadêmico tradicionalmente encarregado de mobilizar o pensamento de Bakhtin e o Círculo, eles projetam a discursividade teórica para o universo estético, comprovando a hipótese de que arte e ciência podem estabelecer inesperados e produtivos diálogos.
The Institutional Capacity Building of Al-Ittifaqiah Islamic Boarding School Based on Entrepreneurship
Authors: Yunindyawati Yunindyawati , Lidya Eva , Erina Lili , Agus Susanto Tri
Published: August 2023

This study aims to analyze Islamic boarding schools’ institutional capacity building to improve entrepreneurship among students. The method used is mixed. The data were collected through in-depth interviews. Observations are made by observing the daily activities of the boarding school in carrying out its roles and functions. The results of this study indicate that the institutional capacity building is carried out in a long and continuous. Normatively, it is arranged in the vision and mission and practically through various program activities that encourage the implementation of the vision and mission of the Islamic boarding school. Efforts to develop the institutional capacity of the cottage institutions are carried out by developing the ability of life skills, talents and potential based on the conditions and situations of the boarding school and students. Islamic boarding schools also carry out socio-economic adaptations in line with global developments and the digital era.
c нервной системы
Authors: Абдуллина А.М. , Слободян А.С.
Published: August 2023

Данная статья отображает результаты исследования в развитии ЛФК (лечебной физической культуры) при заболеваниях центральной нервной системы. В настоящее время достаточно большое количество людей сталкиваются с проблемами центральной нервной системы. В медицине, на сегодняшний день, для каждого отдельного вида заболевания предусмотрен комплекс физических упражнений, направленный на поддержание работоспособности, без ущерба здоровью.
Развитие физических качеств у студентов на занятиях по силовой аэробике
Authors: Гречка П.А. , Шеронов В.В.
Published: August 2023

В статье были рассмотрены основные аспекты занятий силовой аэробикой. Был подчеркнут тот факт, что силовая аэробика крайне благотворно влияет на общее состояние человека. Выявлены определѐнные проблемы в процессе занятий силовой аэробикой.
Оптимальный вес и способы его сохранения
Authors: Евтропкова Д.С.
Published: August 2023

Целью исследования, результаты которого представлены в данной статье, является изучение критериев оптимальной массы человека, поиск способов его сохранения, проведение анкетирования по данной теме и анализ результатов.
Физическая культура в период профессионального становления студента
Authors: Липовская М.Р.
Published: August 2023

В статье рассматриваются вопросы значения физической культуры и спорта для студенческой молодежи. Влияние физкультуры и спорта на здоровье, на естественное развитие, воспитание, здоровый образ жизни.
Адаптация ценностей физической культуры для людей с ограниченными возможностями
Authors: Постнова А.Д. , Хайруллин И.Т.
Published: August 2023

В данной статье рассматривается проблема адаптации ценностей для физической культуры для людей с ограниченными возможностями. Она обращает внимание на важность инклюзии и равноправия в обеспечении доступа и участия в физической активности и спорте для всех. Также рассматриваются практики адаптации, такие как разработка специальных программ, инклюзивные тренировки, обучение тренеров, создание доступной инфраструктуры и информационная поддержка. Подчеркиваются преимущества, которые адаптация ценностей для физической культуры предоставляет, включая физическое и психологическое благополучие, социальную интеграцию, повышение самооценки и расширение возможностей.
Настольный теннис
Authors: Севодин С.В. , Зейтуллаев Р.С.
Published: August 2023

Динамическая игра, называемая настольным теннисом, помогает концентрации внимания, развитию реакции и двигательной активности. Уметь хорошо играть в настольный теннис – это большое искусство. Надо уметь бороться до конца, не сдавай своих позиций ни при каких обстоятельствах, даже если твой соперник намного сильней тебя. Данная статья содержит практические советы для игры в настольный теннис.
Оценка состояние и пути формирования физической культуры личности студентов технического вуза
Authors: Токарева А.А. , Хайруллин И.Т.
Published: August 2023

Проблема оценки состояния и путей формирования физической культуры личности студентов – одна из немногим проблем, которая затрагивает почти всех студентов технической направленности. Данная статья более подробно описывает методы и результаты исследования текущей проблемы. Для совершенствования показателей эффективности процесса обучения предлагаются различные пути улучшения форм и методов организации обучения.
Взаимосвязь физического развития и когнитивных данных студентов
Authors: Шаргунов С.А. , Севодин С.В.
Published: August 2023

Еще Конфуций отмечал, что во всем должна отмечаться гармония и «золотая середина». В жизни каждого человека все должно быть гармонично. Гармония физического состояния тела должна быть в одинаковой пропорции когнитивным потенциалом человека. Однако эти знания не даются современной молодежи, редко кто об этом знает. Физическое развитие зависит от движения тела человека, занятий спортом, упражнениями, дающими определенную нагрузку на костную и мышечную систему. Оно имеет непосредственное влияние на моторику мозговой деятельности и состояние нервной системы в целом. В статье приводится доказательство вышесказанному благодаря проведенным антропометрическим и физиологическим параметрам измерений показателей организма студентов 17-18 лет.
Технологии криптографической защиты в системе связи ВС РФ: проблемы и перспективы
Authors: Данилюк А.И. , Чеботарь И.Т , Вахненко И.В
Published: August 2023

В настоящее время информационная безопасность является одной из ключевых проблем, с которыми сталкиваются государства и организации по всему миру. Военные структуры, в том числе Вооруженные Силы Российской Федерации (ВС РФ), не являются исключением. Криптографическая защита в военных системах связи играет важную роль в обеспечении конфиденциальности и целостности передаваемой информации. В данной статье рассматриваются существующие технологии криптографической защиты связи в ВС РФ, а также анализируются проблемы и перспективы их дальнейшего развития.
Применение сингулярного разложения для понижения размерности в анализе данных
Authors: Минин А.С.
Published: August 2023

В данной работе исследованы математические основы сингулярного разложения (SVD), а также пример его применения для анализа и обработки данных о сервисном обслуживании автомобилей одного из ведущих отечественных автопроизводителей. Актуальность практического применения сингулярного разложения обусловлена необходимостью в эффективных методах анализа и обработки большого объѐма данных с целью понижения их размерности без потери ценности информации. Целью данной работы является изучение и анализ метода сингулярного разложения в контексте понижения размерности данных.
Искусственный интеллект и ограничение входных данных как ключ к эмуляции человеческого мышления
Authors: Тищенко И.Ю , Тищенко Д.Ю , Завгородний С.А , Бережанская С.А
Published: August 2023

В данной статье исследуется гипотеза о необходимости ограничения входных данных для эмуляции человеческого мышления и реализации искусственного интеллекта. Основываясь на обзоре литературы и практических примерах, исследование выявляет значимость входных данных для обучения нейронных сетей и предлагает практические методы ограничения входных данных для достижения эмуляции человеческого мышления
Автоматизация технологического процесса контроля и проверки абонентского модуля коммутационной станции
Authors: Шведун О.А , Назарова И.Т.
Published: August 2023

В данной статье рассмотрены виды систем контроля и управления технологическими процессами, основные элементы бережливого производства, а также общая структурная схема системы контроля и управления; проведена работа по совершенствованию процесса проверки и контроля абонентского модуля коммутационной станции, а именно предлагается использовать распределительную коробку.
Automation of the propane evaporation unit In the production of hydrogen
Authors: Kurakin D.S., , Tokarev S.V , Kuligina N.O
Published: August 2023

The article examines the efficiency of a hydrogen production enterprise, which can be positively influenced by technically improving the node with the raw material capacity through which liquefied propane passes. The main working processes are considered. The article considers that the high-quality operation of this raw propane unit under consideration will ensure the continuous supply of liquefied propane. As a result, the author of the article puts forward the opinion that the continuous supply of liquefied propane will ensure an increase in the efficiency of the hydrogen production plants
New centrifugal nozzle
Authors: Utekhina A.V , Zaitsev A.A , Kosyrev V.M , Tarlakovskaya E.A
Published: August 2023

This article is devoted to the creation of a centrifugal nozzle NMT-M. The principle of operation and disadvantages of the NMT nozzle, which served as an analogue for the creation of the NMT-M, are described. New design features of the NMT-M nozzle are described. The principle of operation of the nozzle is given. The results of the experiments with various debalances for the NMT nozzle are presented, the dependence of performance on the inlet pressure is presented.
Управление потокораспределением на индивидуальных тепловых пунктах систем централизованного теплоснабжения
Authors: Харин И.А
Published: August 2023

Управление потокораспределением в тепловых сетях способствует повышению энергоэффективности централизованного теплоснабжения. Использованы известные математические методы гидравлического расчета теплопроводов, предложен метод оценки работоспособности сетей централизованного теплоснабжения, позволяющий обоснованно актуализировать Схему теплоснабжения
Анализ дефектов микросварного соединения золото-алюминий в корпусах микросхем
Authors: Дротенко В.Д , Соловьев И.А , Вертянов Д.В , Калугин В.В.
Published: August 2023

В данной статье рассмотрены дефекты микросварного соединения золото-алюминий в корпусах микросхем, возникающие со временем при воздействии повышенной температуры. В работе представлены этапы образования пустот Киркендалла. Приведены факторы, влияющие на прочность, пластичность и хрупкость микросварного соединения золото-алюминий
Электрические установки сельскохозяйственного назначения
Authors: Волкова Ю.С.
Published: August 2023

Электрооборудование играет важную роль в современных сельскохозяйственных установках, обеспечивая питание для освещения, отопления, вентиляции, орошения и других важных функций. Однако электрическое оборудование также может представлять значительный риск для безопасности, особенно при воздействии влаги, пыли и других факторов окружающей среды. Чтобы свести к минимуму эти риски, фермеры должны следовать строгим правилам установки и обслуживания, включая процедуры заземления и соединения, регулярные проверки и надлежащее использование защитного оборудования. Кроме того, электрические системы должны соответствовать местным нормам и правилам, которые могут различаться в зависимости от типа и размера установки.
Типология конструкций и технологий возведения подпорных стен
Authors: Никитина В.С , Лапшина Е.А. , Лиханский Ю.И
Published: August 2023

В статье впервые систематизируются существующие и принципиально новые типологии конструктивных систем подпорных стен, а также технологии их возведения. Классификация подпорных стен проведена с учѐтом действующих на неѐ нагрузок - опрокидывание и сдвиг. Кроме этого, рассмотрены передовые технологии строительства подпорных сооружений, которые позволяют создать искусственный рельеф – крупномасштабную геопластику.
Cпособы защиты автомобильных дорог от снежных заносов
Authors: Павлова Л.Н , Коннов Д.А
Published: August 2023

В статье рассматривается способы защиты автомобильных дорог от снежных заносов. Рассмотрены такие способы как очистка механизированными снегоочистителями, минипогрузчиками, применение различных противогололедных материалов, устройство обогрева автомобильных дорог и применение тепловых насосов работающих по принципу воздух-вода.
Этнопсихологические особенности тунгусов в описаниях путешественников и исследователей сибири XVII– начала ХХ вв.
Authors: Алексеева С.А
Published: August 2023

В данной статье дается описание этнопсихологических особенностей тунгусов в трудах путешественников по Сибири XVII– начала ХХ вв. Этноспецифические черты характера тунгусов, дававшиеся им в работах авторов этого периода, зачастую отчетливо выделялись своей ярко выраженной благожелательностью. Следует отметить, что архаические поведенческие модели, ранние культурные нормы формируются в культурном пространстве каждого народа и максимально адекватны обстоятельствам того или иного исторического периода
Образ и наследие В.И.Ленина в зарубежной историографии/ на примерефранцузской исторической школы «Анналов»
Authors: Максимов С.Н , Симанин О.В
Published: August 2023

В статье раскрывается как менялось восприятие личности В.И.Ленина на страницах одного из ведущих исторических журналом Европы «Анналы» и в книгах представителей данной школы. К марксизму обращались основатели школы –М.Блок и Л.Февр. Личность В.И.Ленина практически самостоятельно вплоть до конца 80-х годов ХХ века- до эпохи «перестройки» рассматривалась вскользь. Но и здесь в статье выделяется основные направления. Крупнейший специалист в области русской революции 1917 года М.Ферро в своей книге, посвящѐнной событиям 1917 года признавал за большевиками и конкретно В.И.Ленина умение использовать 'разгул анархии', пробуждение в массах 'врожденной жажды насилия и погромов‘, что явилось проявлением ‗векового инстинкта' русского народа к разрушению, ниспровержению любых порядков и авторитетов для прихода к власти. В статье приводятся взгляды историка Пьер Суйри который в своей работе подчѐркивал, что все большевики во главе с В.И. Лениным объявляли об упадке капитализма, опираясь на тенденциозный закон падения нормы прибыли, веря, что в слишком далеком будущем наступит время кризиса капиталистической системы и время ее свержения. В период «перестройки» возникает интерес к личности В.И.Ленина. Историк из семьи эмигрантов Владимир Берелович изучая дискуссии о сути советского режима делал интересные замечания о политике В.И.Ленина.
Реакция стран Востока и Азии на открытие второго фронта в Европе 1944 году
Authors: Ширшова Е.А.
Published: August 2023

В статье рассматриваются реакции стран Востока и Азии на открытие второго фронта в Европе во время Второй мировой войны. Рассматривается вопрос о том, какую реакцию В Турции, Египте вызвало такое событие. Автор обращает внимание на роль СССР и Китая в поддержке антигитлеровской коалиции и их вклад в победу над фашистской Германией. Также рассматривается реакция Японии, которая не приняла участия в конфликте на европейском театре войны, но продолжала борьбу на Тихом океане. В целом, статья показывает, что открытие второго фронта в Европе имело важное значение для всей мировой истории и вызывало различные реакции у разных стран
Диагностика уровня стресса и запаса адаптации у различных форм и сортов вишни по показателям эндофитной микробиоты
Authors: Кружков , А.В. , Козаева М.И.
Published: August 2023

Путем ежемесячного тестирования эндофитной микробиоты различных форм и сортов вишни изучена ее биология, динамика, а также установлен состав микроорганизмов, ассоциируемых с растением. На основе полученных экспериментальных данных проведена диагностика адаптационной способности изучаемых сортов и форм вишни и выделены наиболее ценные из них для селекции, а также для использования в любительском и промышленном садоводстве, что позволит повысить экономическую эффективность выращивания культуры вишни.
Повышение взаимодействия и качества оказания транспортно-логистических услуг промышленных предприятий и станций примыкания
Authors: Солоп И.А.
Published: August 2023

В статье рассмотрены вопросы, направленные на повышение эффективности работы станции примыкания во взаимодействии с предприятием АО «Невинномысский Азот», который является основным грузоотправителем станции и входит в группу АО «МХК Еврохим». Проанализирована номенклатура выпускаемой продукции АО «Невинномысский Азот», направления поставок, финансовые результаты и перспективы расширения продуктовой линейки. Рассмотрены технологические методы взаимодействия станции и предприятия, предложены мероприятия, позволяющие повысить уровень взаимодействия и качество оказания транспортно-логистических услуг.
Electric train carriage with a variable floor level concept
Authors: Saitov R.I , Isajeva S.M
Published: August 2023

The article discusses a head non-motorized car with a variable floor level, its layout scheme, technical specifications, advantages and disadvantages of the chosen solution
PSYCHOSOCIAL ASPECTS OF INFORMED VOLUNTARY CONSENT IN DENTAL PRACTICE
Authors: Chernavskiy Aleksandr , Belova Olga , Kolyadina Alexandra
Published: August 2023

The reason for the psychosocial discomfort in the majority of dentists when providing medical care at the present time is not the difficulties in providing dental care and services, namely the changes that have occurred in terms of obtaining informed voluntary, informed, written consent to the invasion of the sphere of physical and personal integrity, as well as the need for a doctor to help comprehend and explain to the patient the conditions, on which medical intervention will be performed. Healthcare organizers and medical workers are often not ready to carry out organizational and psychological changes themselves, and in order to optimize the processes of digitalization, it is necessary to build psychological cross-counseling of workers to overcome difficulties in interacting with patients.

The subject of the study is the awareness of doctors about the importance of informed voluntary consent in dental practice.

The relevance of this study is due to the need to standardize the process of obtaining informed voluntary consent for medical intervention from patients of dental institutions.

The aim of the study is to develop the concept of organizational and psychological determinants that determine the role of IDS in the context of the effectiveness of interaction between a dentist and a patient.

Methodology. The general scientific methodology of the study was determined by the following principles of consideration of complex social objects: consistency, determinism, unity of consciousness and activity, development.

We relied on the general psychological theory of activity, the concept of the development of professionalism and the image of the professional world. The study used methodological and theoretical foundations of the analysis of labor activity, the concept of group training; the theory of planned and step-by-step formation of actions.

Conclusions. The concept of informed consent and its role in dental practice is analyzed. The reasons of insufficient awareness of medical workers and patients as a source of conflict situations and a factor of dissatisfaction of patients in dental practice are investigated. The impact of insufficient patient awareness on various aspects of the work of dental organizations was assessed. Organizational standardized solutions to problems in informing the patient are proposed.
ASSESSMENT OF THE STRESS LEVEL OF DENTISTS BASED ON THE CORTISOL CONTENT IN SALIVA
Authors: Lavrent'eva Ol'ga , Makeeva Maria , Gevorkyan Aleksey , Pilshchkova Olga , Butaeva Natalia , Shevelyuk Yulia , Pobozhyeva Ludmila , Bophoev Saddam
Published: August 2023

Aim. Based on the cortisol content in the oral fluid and the assessment of emotional stress, determine the stress level of dentists.

Materials and methods. The group consisted of 25 healthy volunteers, dentists (8 men and 17 women aged 24 to 60 years) with various work experience. Participants filled in an adapted scale of the level of emotional stress before the start of the work shift. On the same day, oral fluid was collected to assess cortisol levels in the morning and evening.

Results. There were no statistically significant differences in the level of emotional stress among dentists, depending on gender. The level of emotional stress in general increases with increasing work experience. With an experience of more than 20 years, emotional stress is significantly (p = 0.026) higher compared to colleagues who have been in the profession for less than 10 years, the indicator was 16.43 (±3.20) and 19.00 (±1.10) points, respectively. The level of evening cortisol in the oral fluid has a statistically significant relationship of noticeable strength with the level of emotional tension only in participants with a high level of tension (18–20 points).

Conclusions. The level of emotional stress increases with increasing work experience as a dentist. To assess the level of stress, the level of evening cortisol is more indicative than in the morning, and the interpretation of the results should be carried out in conjunction with the assessment of emotional stress, as well as considering the somatic status of the subject.
EXPERIMENTAL AND MATHEMATICAL DETERMINATION OF DEFORMATION RISKS OF DENTAL MATRICES DURING ANATOMICAL ADAPTATION TO THE PROXIMAL SURFACE OF THE TOOTH
Authors: Shefov Vladimir
Published: August 2023

Introduction. Creating high-quality interdental contacts is the most important and difficult step in the treatment of proximal caries. In modern dentistry, most methods for restoring the proximal wall of teeth involve the use of dental matrices. The choice of matrix and the peculiarities of working with it are the determining factor in the formation of the proximal contour of the tooth and often causes difficulties, especially for young specialists.

The aim of the study is to conduct an experimental-mathematical determination of the tensile strength of dental matrices to elastic deformation based on the curvature of the proximal surface of the chewing teeth.

Materials and methods. The work consisted of 2 stages. Initially, a test bench was developed to assess the deformation capabilities of dental matrices, consisting of a strain gauge and a model of the proximal tooth wall with the possibility of fixing the matrix and imitating pushing. The model was created in SolidWorks software and 3D printed from light-cured polyamide. At the second stage, computer models of teeth and matrices were created, as well as an analysis of data from x-rays and other sources.

Results. In the course of the work, the strength characteristics of dental matrices were obtained, the limits of their deformation capabilities were determined depending on the thickness of the material and the area of impact on it. Titanium matrices have the best strength characteristics, withstanding a force of 70 N, with an impact area of 2.25 mm2. An analysis of the curvature of the proximal surfaces of the chewing teeth revealed the best match between the matrix contour and the tooth contour on the medial surface of the first molars of the upper and lower jaws.

Conclusions. To achieve high results in the restoration of the proximal walls of the teeth, in most cases it is recommended to press the matrix with an instrument with a working area of at least 2 mm2.
Awareness of sustainable finance development in the world from a stakeholder perspective
Authors: Rani Asni Mustika , Dariah Atih Rohaeti , Madhoun Wesam Al , Srisusilawati Popon
Published: August 2023

Sustainable finance is one way to realize a new paradigm of sustainable development that incorporates social and environmental issues into economic calculations. However, in its implementation, each country faces different challenges in making and implementing policies to support sustainable finance. This study will analyze the public perception of Muslim-majority and Muslim-minority countries towards the implementation of sustainable finance in their respective countries and then analyze the stages of implementing sustainable finance. To analyze the level of implementation of sustainable finance, this study uses the concept of Attention-Interest-Desire-Action (AIDA). To collect data about the object of research using the methods of content analysis and field studies. Content analysis is all the efforts made by researchers in gathering information relevant to documents that explain the background of the existence of sustainable finance and its implementation in several countries. The field study is used to collect primary data regarding perceptions related to the context of sustainable finance, which can be used to determine the proportion of activities that substantially contribute to environmental objectives (climate change mitigation and adaptation efforts). Research results show that there is no difference in the views of respondents as development stakeholders regarding the implementation of sustainable finance in both Muslim-majority and minority countries. The majority of the two categories of country groups are still at the interest stage, reflected in high scores in normative statements and low scores in positive statements that describe real activities in running a sustainable finance system.
The Combined Effect of Donepezil and Lovastatin on the Electrical Activity of Hippocampal Pyramidal Neurons in a rat model of Alzheimer’s disease
Authors: Eskandary Azade , Moazedi Ahmad Ali
Published: August 2023

Background: Donepezil, a noncompetitive acetylcholinesterase inhibitor, is prescribed to treat mild to moderate Alzheimer's disease but it only has moderate performance. Therefore, combination therapies are more effective. There is much evidence suggesting that statins have neuroprotective effects on neurological disorders including Alzheimer's disease. The present study aimed to investigate the combined effects of Donepezil and Lovastatin on the activity of the pyramidal neurons of the CA1 hippocampus.
Methods: In the present experiment study, adult male rats were divided into 3 groups: Nucleus Basalis Magnocellularis (NBM) lesion (which received electrically- induced lesion (0.5 mA, 3s) in NBM) group, NBM lesion + injection Donepezil 5mg/kg-Lovastatin 10mg/kg, NBM lesion+ injection Donepezil 15mg/kg-Lovastatin 30mg/kg. Spontaneous activity of pyramidal neurons in CA1 region to injection of Donepezil-Lovastatin was investigated in a rat model of Alzheimer's disease.
Results: The results of this study showed that electrical lesion of NBM leads to a decrease in the activity frequency of pyramidal neurons in the CA1 region. Administration of Donepezil 5mg/kg-Lovastatin 10mg/kg increased the frequency of pyramidal neurons in rat model of Alzheimer's disease.
Conclusion: The results of this study suggest that co-administration of Donepezil-Lovastatin (low doses) increases the activity of the CA1 pyramidal neurons in a rat model of Alzheimer’s disease.
Relationship between the aortic valve calcification and gradient with carotid stenosis severity and plaque’s morphology in patients with ischemic stroke
Authors: Sadeghi Mohammadreza Taban , Khalili Ahmadali , Safaei Naser , Hadi Sakine , Golmohammadi Ali , Hokmabadi Sonia Shearbafian , Khezerlouy-Aghdam Naser
Published: August 2023

Objectives: The relationship between aortic valve calcification (AVC) and aortic valve outflow gradients with carotid artery stenosis (CAS) has been discussed and debated. The present study aims to investigate the relationship between AVC and CAS with the presence and severity of CAS.
Methods: In this cross-sectional study, we collected carotid artery (CA) Doppler ultrasonography and echocardiography results from 150 patients hospitalized for ischemic stroke. The case group consisted of 75 patients with an atherosclerotic plaque in the carotid artery with >50% stenosis. Seventy-five patients without atherosclerotic plaques in the carotid artery were included in the control group.
Results: AVC and AV peak gradients were significantly higher in the case group compared to the control group (p=0.0001, p=0.015) respectively. In the case group, there was no significant association between AVC and AV peak gradient with the severity of CAS and between AVC and carotid plaque morphology (p=0.88, p=0.14, p=0.089) respectively. The two groups had no significant difference in the rate of aortic regurgitation (AR) (P=0.57).
Conclusions: Aortic valve calcification and aortic valve gradients are significantly related to CAS. AVC and aortic valve gradients could be considered risk factors for CAS and stroke. Contrary to this, the severity of gradients and AVC was not directly related to the severity of CAS and its morphology.
Effect of celecoxib on intra-abdominal sepsis-induced lung injury in rats
Authors: DIBEKOGLU Cengiz , BORA Ejder Saylav , EROĞLU Ebru , YURTSEVER Guner , UYANIKGİL Yiğit , ERBAŞ Oytun
Published: August 2023

Objectives: This experimental study investigated the preventive effects of Celecoxib, a selective COX-2 inhibitor, on lung injury induced by intra-abdominal sepsis in rats. The study assessed Celecoxib's potential to mitigate the harmful impacts of sepsis on lung tissue.
Methods: Thirty male Wistar albino rats, divided into three groups: a normal control group, a sepsis-induced group treated with saline, and a sepsis-induced group treated with Celecoxib. Sepsis was induced using fecal intraperitoneal injection (FIP), followed by a one-hour administration of Celecoxib at 50 mg/kg/day to the treatment group. Biochemical analysis of lung tissue measured oxidative stress markers (malondialdehyde [MDA]) and pro-inflammatory cytokines (Tumor Necrosis Faftor-α [TNF-α]). Histopathological examination evaluated lung tissue damage, encompassing alveolar congestion, hemorrhage, inflammatory cell aggregation, and edema. Arterial blood gas analysis quantified partial oxygen (PaO2) and carbon dioxide (PaCO2) pressures.
Results: Celecoxib-treated rats exhibited reduced oxidative stress markers with lower MDA levels, indicating decreased oxidative damage in lung tissue. Moreover, TNF-α and other pro-inflammatory cytokines were significantly reduced in lung tissues of Celecoxib-treated rats, indicating its anti-inflammatory effects. Histopathological examination revealed reduced lung tissue damage in Celecoxib-treated rats, including alveolar congestion, hemorrhage, and inflammatory cell aggregation. Arterial blood gas analysis showed improved oxygenation (PaO2) in the Celecoxib-treated group compared to untreated sepsis rats.
Conclusions: Celecoxib demonstrated preventive effects against sepsis-induced lung injury in rats by mitigating oxidative stress and inflammation, thereby preserving lung tissue integrity—further research, including clinical trials, to validate its effectiveness and safety in human sepsis management.
Relationship between uric acid/ albumin ratio and coronary slow flow
Authors: DEMİRKIRAN Aykut , AYDIN Cihan
Published: August 2023

Objectives: Although the pathophysiology of coronary slow flow is not fully understood, evidence suggesting endothelial dysfunction and subclinical widespread atherosclerosis in genesis has grown in recent years. Our aim in this study is to investigate the relationship between uric acid/ albumin ratio and coronary slow flow.
Methods: One hundred and five coronary slow flow patients (determined by the Thrombolysis in Myocardial Infarction-frame count method) and one-hundred patients with normal coronary low were included retrospectively. The uric acid/ albumin ratio was investigated in all patients participating.
Results: In the logistic regression analysis, it was revealed that high uric acid levels, uric acid/ albumin ratios, and male gender were independent predictors for coronary slow flow. Among these parameters, the uric acid/ albumin ratio was the best predictor of coronary slow flow. Based on the receiver operating characteristics (ROC) analysis, the cut-off value of uric acid/ albumin ratio ≥ 0.57 was found to predict coronary slow flow with 68.3% sensitivity and 68.7% specificity. In multivariate logistic regression analysis, high uric acid levels (OR: 2.22; 95% CI (1.551-3.200), p < 0.001), high serum uric acid/ albumin ratio (OR: 37.7 95% CI (8.176-234.387), p < 0.001), male gender (OR: 0.157; 95% CI (0.078-0.318), p < 0.001) were independent predictors of coronary slow flow.
Conclusions: High uric acid/ albumin ratio was detected as an independent predictor for coronary slow flow. Larger studies are needed to elucidate its role in the pathophysiology of coronary slow flow.
La Ilustración como desafío para nuestro presente: algunas notas acerca de la Ilustración en Alemania
Authors: Vázquez Lobeiras María Jesús
Published: August 2023

El presente artículo contiene una aproximación historiográfica al desarrollo de la Ilustración en Alemania, considerando las características específicas de la misma frente a Inglaterra o Francia, así como sus etapas. Se expone asimismo la tipología de sus ideas principales elaborada por Norbert Hinske y se hace balance acerca de su posible vigencia e interés para la actualidad, con atención especial a la idea de una razón humana universal y de la destinación del ser humano.
Modeling of processing capacity of terminal and logistics facilities of the Nizhneleninskoye (RF) –Tongjiang (PRC) railway border crossing
Authors:   Far Eastern State Transport University (FESTU), Korol R. G. , Podolinnaya S. D. ,   Far Eastern State Transport University (FESTU)
Published: August 2023

The workload of terminal and warehouse facilities of the transport and logistics center «Nizhneleninskoye» under construction, accompanying the railway bridge crossing Nizhneleninskoye (RF) - Tongjiang (PRC), is investigated. The transport and terminal logistics infrastructure of the Nizhneleninskoye - Tongjiang border crossing is considered. The paper uses theoretical research methods, including modeling, visualization and comparison. Crossborder infrastructure projects, including railway and automobile bridge crossings, are considered, indicating the existing and prospective capacity. The technical and operational characteristics of the transport and terminal logistics infrastructure of the Nizhneleninskoye - Tongjiang railway border crossing are given. The technical and technological parameters of the warehouse complex of the transport and logistics center Nizhneleninskoe are described. The results of two modeling scenarios are presented - at the first stage of operation of the transport and logistics center «Nizhneleninskoe» and at the second stage of operation with infrastructure development for prospective cargo handling. With the increase in the incoming cargo flow by 2.5 times at the second stage of operation of the warehouse complex, during the simulation, the load of the storage area of the warehouse complex increased by 40%, the load of lifting and transport equipment increased, which affected the reduction in the number of handled and shipped loaded vehicles. In order to speed up intra-warehouse operations, it is proposed to develop options for moving lifting and transport equipment, designate «hot» and «cold» zones of the warehouse, determine the required staff numbers with distribution by working positions, draw up technological maps and daily work schedules of the warehouse.
Research on properties of the combination-type device fault-tolerant structure implemented by the logical correction method of signals with calculation testing by modified Hamming’s codes
Authors:   Russian University of Transport (RUT-MIIT), Efanov D. V. , Pogodina T. S. ,   Russian University of Transport (RUT-MIIT)
Published: August 2023

A fault-tolerant structure for combinational-type automation devices is considered, which does not imply the introduction of modular precision into the structure of the original device. In the fault-tolerant structure, using the method of logical correction of signals, a special block for fixing distorted signals is synthesized, and using a modified Hamming code, a concurrent error-detection circuit for the source object is synthesized. Correction is carried out using the output signal correction unit controlled by the concurrent error-detection control circuit and block for fixing distorted signals. This allows us to correct errors at any outputs of the source device, which are fixed by the concurrent error-detection circuit. Compared to parity codes used to control calculations testing, Hamming codes have improved detecting ability, which reduces the probability of error masking. An example is given demonstrating the process of modeling the operation of the fault-tolerant structure in case of occurrence of single stuck-at faults in it. The proposed method for synthesis of a fault-tolerant device could be used in implementation of automation and computer technology devices.
Analysis of long-term trends in passenger traffic in intermunicipal bus transportation service
Authors:   Ural state university of railway transport (USURT), Martynenko A. V. , Vakolyuk K. K. ,   Ural state university of railway transport (USURT)
Published: August 2023

Transport infrastructure planning and transport policy decisions are important in the issue of regional governance. Bus transportation service is non-alternative for many destinations, therefore it requires understanding of future trends in order to make more grounded decisions. The intermunicipal bus transportation market depends on the general mobility of the population and personal preferences of passengers. Transport behavior is a dynamic characteristic which is influenced by a variety factors. In the long term, it is affected by socio-economic indicators, offers of competing modes of transport, etc. This article analyzes various factors which have an impact on intermunicipal passenger traffic in the Sverdlovsk region. In addition to socio-demographic factors, a change in the transport behavior of the population caused by the sanitary and epidemiological situation and development of the sharing economy, namely, the spread of travel companion search services, is considered. Several scenarios of long-term changes in passenger traffic trends based on causal analysis and mathematical modeling of time series are proposed. In particular, an additive model based on a component-by-component decomposition of a time series and a model of triple exponential smoothing by Holt - Winters are applied.
The impact of economic sanctions on the production and repair of innovative railcars
Authors:   Ural state university of railway transport (USURT), Smolyaninov A. V. , Lapshin V. F. ,   Ural state university of railway transport (USURT), Koljasov K. M. ,   Ural state university of railway transport (USURT), Cherepov O. V. ,   Ural state university of railway transport (USURT)
Published: August 2023

Economic sanctions against the railcar building and repair industries have affected the production of cassette bearings of axle boxes used in the production and repair of innovative railcars. Cassette bearings have a number of significant advantages (unique abilities of conical rolling bodies, compactness, small size and others) that allow to realize loads from the axle to the rails of 245 kN (25 tf) or more and thereby increase the gross weight of railway cars to 108 tf. Withdrawal of manufacturers producing bearings from the Russian market (Timken, SKF, Brenko) led to a sharp drop in the production and repair of innovative rail-cars. A comparison of the production volumes of rail-cars in February and May 2022 discovered that there was a significant reduction (at JSC «Uralvagonzavod» and JSC «Tikhvin Railway Car Building Plant»), and by August production had practically stopped. The sanctions forced companies producing bearings (EPK-Brenko, Tek-Com Production) and railcar repair companies to search for new suppliers of components, primarily bearings. Such supplier companies could be Wafangdian (ZWZ), Luoyang LYC (China) and SPZ Bearings (Uzbekistan). As a result of the measures taken and the significant intensification of work, it is assumed that a significant part of the demand for bearings will be covered by domestic plants. The sanctions intensified the refinement and stimulated the production of twincylindrical roller bearings, which, according to preliminary test results, demonstrated the same durability resources as conical cassette bearings (eight years of operation and 800 thousand km of mileage). The paper analyzes and presents the statistics of the production of domestic railcars equipped with cassette-type bearings, and the challenges associated with their production.
Optimization of inventory rails and rail-sleeper grid using RFID technology
Authors:   Ural state university of railway transport (USURT), Kargapoltsev Dmitry V. , Kalashnikov Andrey E. ,   Ural state university of railway transport (USURT), Maigov Ruslan Yu. ,   JSC “Russian Railways”
Published: August 2023

The article analyzes the existing process of tracing the life cycle of inventory rails and the rail-sleeper grid within the Sverdlovsk Directorate for Track Repair. A number of problems have been identified that are proposed to be solved using RFID technology. The expediency of automating the rail accounting process is emphasized, the advantages of implementation are determined. The relevance of the topic is due to the implementation of the Digital Transformation Strategy of JSC “Russian Railways” and the company’s interest in ensuring transparency of the life cycle of tangible assets.
Overview of international standards in the fi eld of quantum communications
Authors:   Ural state university of railway transport (USURT), Rusakova Elena A. , Paschenko Mikhail A. ,   Ural state university of railway transport (USURT)
Published: August 2023

Currently, quantum technologies are actively developing in the world. In the Russian Federation, the curator of this direction is JSC “Russian Railways”, which initiated the development of national standards in the field of quantum communications and quantum Internet. The article examines the main international organizations dealing with standardization issues in the field of quantum communications, provides the overview of the main international standards in the field of quantum communications.
Prospects for the development of tram transport systems on the example of the city of Yekaterinburg
Authors:   Ural state university of railway transport (USURT), Gaisin Ivan A.
Published: August 2023

The article deals with the problems of transport systems of large cities of Russia on the example of Yekaterinburg. A promising transport model of three districts of Yekaterinburg has been developed. As a result of the calculation of the transport model, passenger traffic data for the studied road network, production indicators of public transport were obtained, the analysis of the results obtained was conducted.
CHERNOUSOV LOG – THE NEW LOCATION OF LATE PLEISTOCENE AND HOLOCENE MAMMALS IN THE MINUSINSK DEPRESSION (GEOLOGICAL STRUCTURE AND CONDITIONS OF FORMATION)
Authors:   V.S.Sobolev Institute of Geology and Mineralogy SB RAS, Novosibirsk, Russia, Malikov D. G. , Volvakh A. O. ,   V.S.Sobolev Institute of Geology and Mineralogy SB RAS, Novosibirsk, Russia, Volvakh N. E. ,   V.S.Sobolev Institute of Geology and Mineralogy SB RAS, Novosibirsk, Russia, Savelyeva P. Yu. ,   V.S.Sobolev Institute of Geology and Mineralogy SB RAS, Novosibirsk, Russia, Ovchinnikov I. Yu. ,   V.S.Sobolev Institute of Geology and Mineralogy SB RAS, Novosibirsk, Russia, Malikova E. L. ,   V.S.Sobolev Institute of Geology and Mineralogy SB RAS, Novosibirsk, Russia
Published: August 2023

The paper defines a description of geological structure, conditions of formation and paleofaunistic material from two new locations of fossil mammals within the Minusinsk Depression. Three types of sedimentation are determined for the Chernousov Log section. The upper part of the section is represented by subaerial deposits of the Late Holocene. The middle section part is characterised by traces of soil formation of the Holocene optimum. The lower stratum is represented by alluvial deposits of the Late Karginian-Early Sartanian time. Two locations of mammals dating from the Sartanian and Holocene optimum are identified. The age of faunas is substantiated by their stratigraphic position in the section and results of radiocarbon dating.