bluuebunny/crossref_metadata_2025 huggingface dataset:
Síndrome de Hermansky - Pudlak
Authors: Sá Jônatas Ferreira de , Freitas Yago José Fagundes de , Amorim Gabriela Echenique , Franco Natália Rezende , Nakao Rodrigo Lima , Kakumoto Marília Alves , Sá Jana Lopes de , Silva Sabrina de Castro , Rodrigues Thais Morais , Neme Thais Helena Paro , Salgado Uanda Beatriz Pereira , Velasco Júlia Sanches de , Teston Victória Maria Grandeaux , Alves Filho Robson Pierre Pacífico , Dantas Camila Pizarro , Sousa João Rafael Alencar de , Chagas Jaqueline Maria de Azevedo , Cipriano Fernando Neves , Mocellin Amanda Pereira , Fonseca Abner Lourenço da , Braga Aline Almeida , Pacheco Camila Graziele Fontes , Pereira Franciely dos Passos , Santos Jordânia
Published: November 2023

Introdução: a síndrome de hermansky – pudlak é uma doença genética caracterizada por albinismo oculocutâneo, disfunção plaquetária, e em alguns casos também há colite, insuficiência renal e fibrose pulmonar. Apresentação do caso: paciente, 4 anos, buscou atendimento para investigação de episódios frequentes de gengivorragia, epistaxe e hematomas nos membros inferiores. Discussão: o diagnóstico é realizado pela clínica do albinismo oculocutâneo associada ao déficit placentário e teste genético. O tratamento consiste em acompanhamento multidisciplinar para melhorar a qualidade de vida do paciente. Conclusão: por se tratar de uma doença rara e de difícil diagnóstico é importante compreender a patogenicidade para evitar complicações e fornecer melhor qualidade de vida.
Os impactos socioemocionais no brasil do pós-pandemia de covid-19: um estudo descritivo
Authors: Teixeira Jessica Hellen lima
Published: November 2023

Ao final do ano de 2019, na data de 31 de dezembro, a principal agência internacional de saúde, a OMS, foi comunicada sobre um assunto o que seria uma das maiores notícias dos últimos tempos. Um surto de casos de pneumonia em uma cidade da China, que deu origem a descoberta de um novo vírus. O Coronavírus seria responsável por ocasionar uma doença que deixou um grande rastro de doentes e mortes, a COVID-19. Um vírus nunca antes relatado em humanos, e que se tornaria o causador de uma doença de rápida distribuição geográfica, fazendo com que a OMS declarasse, na data de 11 de março de 2020, pandemia a nível global. Desde então, o mundo entrou em alerta com a COVID-19, doença causada pelo coronavírus (Sars-CoV2), de difícil controle e acompanha as preocupações populacionais devido a forma que se propaga.
Perfil bacteriano encontrado na sedimentoscopia urinária corada de cães com sinais clínicos de cistite atendidos no hospital veterinário da FAVET-UECE: Estudo retrospectivo
Authors: Moreno David de Aguiar , Sousa Gabrielly Nohara de Oliveira Damasceno de , Maciel Julyanna Cordeiro , Batista Katarine Sales , Silva Isaac Neto Goes da , Vasconcellos Amanda Leal de
Published: November 2023

Doenças que acometem o trato inferior são frequentes em cães domésticos, dentre as quais, destaca-se as infecções do trato urinário. Quando a adesão e colonização de bactérias se restringe à bexiga, causam a cistite. Considerando a urinálise, principalmente a bacteriúria, como indicativo de cistite bacteriana, este trabalho surge com o objetivo de realizar um estudo retrospectivo de cães com bacteriúria no período de março de 2018 a março de 2023. Dos 323 laudos de cães, 298 (92,26%) apresentaram infecção simples, enquanto apenas 25 (7,73%) cães apresentaram infecção mista. Quanto a classificação bacteriana encontrada, os cocos gram-positivos apresentaram maior prevalência (46,44%), seguido pelos bacilos gram-negativos (42,10%).
Hiperparatireoidismo em crianças: Manifestações clínicas e conduta cirúrgicas
Authors: Moraes Luís Gustavo de , Toqueton Tainá Rodrigues , Santos Igor Costa
Published: November 2023

O hiperparatireoidismo em crianças é uma condição rara, que representa menos de 1% dos casos. A maioria dos casos é de origem genética ou familiar, associada a síndromes como neoplasia endócrina múltipla, hiperplasia congênita da paratireoide, síndrome de McCune-Albright, entre outras. Seguiu o checklist PRISMA, que consiste em um conjunto de itens essenciais para a elaboração e a divulgação de revisões sistemáticas e meta-análises. Foram realizadas buscas nas bases de dados PubMed, Scielo e Web of Science, utilizando os seguintes descritores: "hyperparathyroidism", "children", "clinical manifestations". Os critérios de inclusão foram: estudos originais em inglês ou português, que abordassem o hiperparatireoidismo em crianças até 18 anos, com dados sobre as manifestações clínicas e a conduta cirúrgica.
Nurses' role in acute coronary syndrome in emergency patients
Authors: Santos Rafael de Carvalho dos , Teixeira Camile Lourenço da Silva , Dovales Camilla de Carvalho , Souza Renata Dantas de , Brazil Isabela Aparecida Rodrigues , Pereira Laryssa de Abreu Fialho Silva
Published: November 2023

Acute coronary syndrome (ACS) is a pathology that annually leads to the death of thousands of people around the world. Every year new statistics emerge, and every year they get worse on the global stage. Thus, the following question was asked: "what would be the role of the nurse in the face of a victim with acute coronary syndrome in the emergency department?" That is why the objective of this study was to describe the performance of nurses in a qualified way in the face of the clinical manifestations of Acute Coronary Syndrome. In view of the severity of the pathology and the high rate of morbidity and mortality, further studies on the subject are extremely relevant to better instruct professionals and disseminate the new protocols for the care of these patients. To do this, we chose to use the methodology in the form of an integrative review, to which throughout the research we came across a total of 35 articles talking about this theme. From this number, we excluded 16 because they were outdated and used 19 to carry out this work. We conclude that good care provided in the emergency room quickly and effectively significantly increases the chances of patient survival and, therefore, we can affirm that the initial approach with emphasis on the prevention of lesions secondary to ischemic myocardial injury is extremely important. Therefore, the health professional should be aware of the signs of poor tissue perfusion, thus preventing these secondary lesions.
Deaths due to accidental submersion in southern Brazil
Authors: Novais Rafael Brendo , Murrugarra Lais Kaori Sato , Luz Kelly Cristina Suzue Iamaguchi , Frez Flávia Cristina Vieira , Oliveira Isabelly Leal de , Sesnik Heitor Hortensi , Murilho Jordhan Abner Teixeira , Dias Giovana Munhoz , Santos Gabriel Vale dos , Sanches Rafaely de Cássia Nogueira , Uema Roberta Tognollo Borotta , Sanguino Gabriel Zanin
Published: November 2023

Introduction: Drowning is the alteration of respiratory function at the level of the trachea, bronchi or lungs, through airway obstruction resulting from submersion/immersion in a liquid medium. The main risk factors for drowning include alcohol and drug use, lack of swimming skills, and a variety of circumstances, including natural disasters and maritime incidents. Drowning mostly happens in children under the age of five, adolescents under the age of 15, and the elderly. Objective: To identify and understand the rates of deaths due to accidental submersion in adults in the southern region of Brazil in 2021. Method: This was a descriptive exploratory study with a quantitative approach. Data collection took place through access to the Ministry of Health's health data platform DATASUS, in the Tabnet health information tab originating from the Mortality Information System (SIM). Results and discussion: In 2021, 79 deaths due to drowning were identified in the southern region of Brazil. Of these, 67 (85%) were male and 12 (15%) were female. Regarding male deaths, 37 (47%) occurred in the hospital and 30 (39%) were identified at home. For females, 4 (33%) deaths occurred in the hospital and 8 (67%) at home. There was a prevalence for both sexes and in both environments, whether hospital or home, they are adults between 20 and 59 years old, with a mean age of approximately 38 years, and most of the time associated with the lack of appropriate supervision. The predominance in relation to race/color was white, with an average of 100% for females, and 49 males (73%), followed by 24% for brown race/color and 3% for black race/color. Conclusion: The incidence of deaths from drowning in the southern region of Brazil in 2021 was higher among hospitalized adult men aged 20 to 59 years, according to literary information. It is understood that drowning is a public health problem and that the spheres of power should spare no effort to reduce the number of deaths from this preventable cause.
The use of acupuncture as a complementary treatment for endometriosis: A systematic review
Authors: Lima Ana Luisa Serrano , Luz Kelly Cristina Suzue Iamaguchi , Sanguino Gabriel Zanin , Felipin Larissa Carolina Segantini , Sampaio Giovana Tófoli , Murrugarra Lais Kaori Sato , Dias Giovana Munhoz , Luckner Ana Clara , Santos Lorraine de Souza , Santoro Fernanda Furlan , Carvalho Rita de Cássia Pereira , Frez Flávia Cristina Vieira
Published: November 2023

Endometriosis is a multifactorial estrogen-dependent and inflammatory gynecological condition characterized by the presence of fragments of endometrial tissue outside the uterine cavity. Due to the negative impact on the physical and psychological appearance of women, endometriosis is considered a public health problem. The Ministry of Health presents the National Policy on Integrative and Complementary Practices (PNPIC), which aims to incorporate and implement experiences outside of Traditional Medicine, among which Acupuncture stands out, a Chinese technique that has proven to be effective for treating pain . This work aims to identify evidence-based recommendations in the literature on the use of Acupuncture and its resources for the adjuvant treatment of endometriosis and is a systematic review of the literature using a pre-established protocol for the search, selection and extraction of data. From this review study, it was possible to verify the therapeutic efficacy of acupuncture as a complementary and integrative treatment for endometriosis, as the technique excites receptors and nerve fibers leading to the release of endogenous opioids, resulting in continuous pain relief. Furthermore, studies have shown that the practice of acupuncture provided greater relief from pelvic pain when compared to the use of drug therapy, in addition to improving the quality of life of women affected by this disease.
Nutritional counseling as a nutrition strategy in palliative care
Authors: Moura Raquel Bezerra Barbosa de , Feitosa Gina Araújo Martins , Olinto Edcleide Oliveira dos Santos , Araújo Pollyana Paula Almeida de , Cavalcanti Isabel Carolina Pinto , Cavalcanti Débora Silva , Araújo Renan Gondim , Lacerda Aline Honor , Cabral Caroline Sousa , Barroso Flávia Nunes de Lima
Published: November 2023

Palliative care is an approach that aims to alleviate suffering and improve the quality of life of patients facing a life-threatening illness, as well as their families and/or caregivers. The nutritionist is an important member of the multidisciplinary team who must act observing the pillars of palliative care, using strategies that seek to relieve symptoms related to food, as well as seeking to nourish the patient in line with their physical, psychological, religious and social aspects. Nutritional counseling is the first nutritional intervention strategy used by nutritionists. Regarding symptom management, this intervention had positive effects on a greater number of symptoms, namely: digestive symptoms, fatigue, dyspnea, inappetence, caloric-protein intake, anorexia, nausea/vomiting, xerostomia, and dysgeusia. Regarding quality of life, early and intensive nutritional counseling, in addition to the use of oral nutritional supplementation, offered positive results in cancer patients receiving radiotherapy, as well as in cancer patients in physical, emotional and social functioning scores. Several studies have also shown that nutritional counseling and the use of oral nutritional supplements, when indicated, lead to improvements in the nutritional status of patients in palliative care. Nutritional counseling is a fundamental step to facilitate nutritional therapy, including strategies that converge expertise and theoretical knowledge and considering each person's feelings, experiences, beliefs, and attitudes. Therefore, it is necessary to establish a bond between the nutritionist and the patient, which will allow them to guide them to necessary changes and improve adherence to nutritional therapy.
Positioning of clothing brands in Colombia
Authors: Jiménez Rendón Jorge Enrique , Garcia Rojas Maribel
Published: November 2023

The positioning of the brand has prominence today in the marketing world thanks to the corporate benefits that are reflected in the market, in Colombia clothing brands year after year have been growing economically, throwing large sales figures and injecting development in the national economy. The objective of this study is to know how is the positioning of clothing brands in Colombia. It is a descriptive study, from a descriptive review with referential sources on the studies that have been carried out regarding the positioning of clothing brands in the Colombian territory. The results indicate that Arturo Calle is the best positioned brand in the market thanks to its high reputation and consumer preference
Mesterséges intelligencia alkalmazása a szarvasmarha-tenyésztés egyes területein: egyedazonosítás, állategészségügy és állatjóllét : Irodalmi összefoglaló
Authors: Tarr Bence , Szabó István , Tőzsér János
Published: November 2023

A Mesterséges Intelligencia (MI) technológiájának alkalmazása az állattenyésztés több területén – állattartás, tenyésztés – vált fontos eszközzé. A szarvasmarhák azonosítása, az egyedek számlálása, valamint ezeknek az információknak a felhasználása az állategészségügyben az egyik olyan lehetőség, ahol az intelligens algoritmusok egyszerűsíteni és gyorsítani képesek az ember munkáját. A szerzők szakirodalmi adatok alapján bemutatják az MI alkalmazásának lehetőségeit elsősorban a szarvasmarhák azonosítására és megszámolására. A mélytanulás ezen belül a neurális hálók használata kiválóan alkalmas a képek szegmentálására és különböző jellemzők alapján azok tartalmi feldolgozására. A konvoluciós neurális hálók kifejezetten az ilyen feladatokban használhatóak jól és a későbbiekben láthatjuk majd, hogy ezeknek a hálózatoknak továbbfejlesztései (pl. Faster R-CNN) még hatékonyabb képelemzési eljárásokat tesznek lehetővé. Az állatokról készült felvételek feldolgozása nagy lépést jelenthet az állatállomány automatizált vizsgálata és azonosítása tekintetében. Ezen rendszerek lehetővé teszik a korai beavatkozást esetleges betegségek megjelenése esetén, és ezzel növelik a gyógyulás esélyét.
Axiological Aspects of Harmonious Formation the Modern Stage of Russian Sovereign Civilization
Authors: Bryndin Evgeny
Published: November 2023

The modern stage of a sovereign country of civilization is being formed in Russia. Russian society faces the urgent task of forming a sovereign multicultural civilization in modern conditions. The harmonious synergetic unity of citizens, peoples, nations and ethnic groups in all spheres of life will help form the modern stage of Russian sovereign civilization. A cultural, professional Orthodox citizen is the pillar of the formation of a Russian sovereign civilization. The harmonization of man and society, the synergy of international interactions will contribute to the formation of a Russian sovereign civilization in modern conditions.
The Influence of Entrepreneurial Orientation and Customer Relationship Management on MSME Competitiveness
Authors: Sembiring Lenny Dermawan , Setyawati Amelia , Indajang Kevin , Putri Juan Anastasia , Sudirman Acai
Published: November 2023

Competitive advantage is realized through continuous sustainability (sustainable competitive advantages), so new strategies must be designed. The strategy designed will certainly be able to dominate both the old market and the new market. The main aim of this research is to analyze the influence of entrepreneurial orientation and customer relationship management on MSME competitiveness. This research uses a literature and field design with a causal associative approach. This study uses a research instrument test consisting of validity and reliability tests. The quantitative analysis consists of a normality test, regression test, hypothesis test, correlation test, and coefficient of determination. Data analysis confirms that entrepreneurial orientation and customer relationship management have a significant effect on MSME competitiveness. The implications of research on entrepreneurial orientation and Customer Relationship Management (CRM) on business competitiveness can provide valuable insights for Micro, Small, and Medium Enterprises (MSME) owners and related parties. Research on entrepreneurial orientation and CRM can help MSMEs develop more targeted business strategies. They can understand how innovation and customer relationship management can be key drivers of their business competitiveness.
THE PREDICTIVE ROLE OF OBESITY FOR MATERNAL AND CHILD HEALTH IN THE FIRST YEAR OF LIFE
Authors: Иванов Д.О. , Прокопьева Н.Э. , Петренко Ю.В.
Published: November 2023

За последние несколько десятилетий распространенность ожирения во всем мире достигла масштабов эпидемии. Ожирение и избыточный вес во время беременности связаны с ухудшением исходов для матери и ребенка. Кроме того, исследования показывают, что материнское ожирение может привести к долгосрочным последствиям для потомства, увеличивая риск развития психоневрологических расстройств, метаболических, атопических заболеваний, а также возможных изменений иммунного / воспалительного статуса. В дополнение к генетическим механизмам все больше данных свидетельствует об индукции эпигенетических изменений материнским ожирением, которые могут влиять на фенотип потомства, тем самым программируя риск ожирения и кардиометаболических заболеваний. Однако механизмы, связывающие материнскую среду с неблагоприятными краткосрочными и долгосрочными последствиями, остаются плохо изученными. В данном обзоре представлены современные знания о влиянии материнского ожирения во время беременности на ребенка в первый год жизни. Понимание этих процессов имеет ключевое значение для разработки терапевтических вмешательств с целью предотвращения будущих сердечно-сосудистых и метаболических патологий у последующих поколений.

Over the past few decades, the prevalence of obesity worldwide has reached epidemic proportions. Obesity and overweight during pregnancy are associated with worse maternal and child outcomes. In addition, studies show that maternal obesity can lead to long-term consequences for the off spring, increasing the risk of neuropsychiatric disorders, metabolic, atopic diseases, and possible changes in the immune / infl ammatory status. In addition to genetic mechanisms, a growing body of evidence suggests the induction of epigenetic changes by maternal obesity, which may infl uence off spring phenotype, thereby infl uencing later risk of obesity and cardiometabolic disease. However, the mechanisms linking the maternal environment to adverse short and long term outcomes remain poorly understood. This review presents current knowledge about the impact of maternal obesity on a child in the fi rst year of life. Understanding these processes is key to developing therapeutic interventions to prevent future cardiovascular and metabolic pathologies in future generations.
AICARDI–GUTIER SYNDROME IN A PATIENT WITH CEREBRAL PALSY
Authors: Айметдинова А.Б. , Завьялова А.Н. , Яковлева М.Н. , Любимова О.В.
Published: November 2023

Редкие наследственные заболевания и их симптоматика являются необычными для врачей, особенно если заболевание гетерогенно, и это представляет серьезную медицинскую проблему. В мире существует около 7000 различных редких заболеваний, из них 80% — генетически детерминированы. Появляется все больше вновь обнаруженных орфанных болезней. Приблизительно 50% пациентов, страдающих редкими заболеваниями, — это дети, что обусловливает важность изучения данных болезней в педиатрической науке. На примере клинического случая рассмотрены проявления синдрома Айкарди–Гутьера у ребенка 17 лет, госпитализированного в клинику СПбГПМУ с основным диагнозом: нефротический синдром при диффузном мембранозном гломерулонефрите. Отражены основные данные анамнеза и клинико-лабораторного обследования. Представлено описание мутаций, приводящих к возникновению синдрома Айкарди–Гутьера, а также формы данного заболевания. Особое внимание отведено дифференциальной диагностике синдрома Айкарди–Гутьера с другими клинически схожими нозологическими формами.

Rare genetic diseases and their symptoms are unusual for doctors, especially if the disease is heterogeneous, and this poses a serious medical problem. There are about 7000 diff erent rare diseases in the world, 80% of them are genetically determined, and more and more newly discovered ones are appearing. Approximately 50% of patients suff ering from rare diseases are children, which determines the importance of studying these diseases in pediatric science. On the example of a clinical case, the manifestations of the Aicardi–Goutieres syndrome in a 17-year-old child admitted to the St. Petersburg State Pediatric Medical University clinic with the main diagnosis: nephrotic syndrome with diff use membranous glomerulonephritis are considered. The main data of history and clinical and laboratory examination are refl ected. The description of mutations leading to the emergence of Aicardi–Goutieres syndrome, as well as the forms of this disease, is presented. Special attention is paid to the diff erential diagnosis of Aicardi–Goutieres syndrome with other clinically similar nosological forms.
NUTRITIONAL APPROACHES TO THE PREVENTION OF OBESITY IN CHILDREN
Authors: Павловская Е.В. , Лебедева А.М. , Строкова Т.В.
Published: November 2023

Профилактика ожирения у детей является приоритетным способом снижения распространенности ожирения и, следовательно, кардиоваскулярного риска как в детской, так и во взрослой популяции. Профилактические мероприятия направлены на коррекцию образа жизни и включают оптимизацию питания и повышение физической активности. В представленном обзоре проанализирована эффективность современных нутрициологических вмешательств, используемых для профилактики избыточной массы тела и ожирения у детей. Подходы, направленные на питание, наиболее перспективны в возрастном периоде от зачатия до 2 лет. Поощрение грудного вскармливания и снижение содержания белка в рационе ребенка в первые 12–24 месяцев жизни снижают риск ожирения в дальнейшие возрастные периоды. Также рекомендуется избегать введения прикорма до 4-месячного возраста. Начиная с двухлетнего возраста применяют подходы, сочетающие изменения в питании и физической активности. Наибольшей эффективностью обладают вмешательства по профилактике ожирения, проводимые в условиях детских образовательных учреждений, в том числе с участием семьи. Перспективными методами коррекции пищевых стереотипов являются средиземноморская диета, сокращение потребления сладких напитков и повышение потребления фруктов, овощей и продуктов, богатых пищевыми волокнами, что оказывает положительное влияние на различные параметры здоровья.

Prevention of obesity in children is a priority way to reduce the prevalence of obesity and, consequently, cardiovascular risk, both in the pediatric and adult populations. Preventive measures are aimed at correcting lifestyle and include optimizing nutrition and increasing physical activity. This review analyzes the eff ectiveness of modern nutritional interventions used to prevent overweight and obesity in children. Nutritional approaches are most promising from conception to 2 years of age. Encouraging breastfeeding and reducing the amount of protein in a child’s diet in the first 12–24 months of life reduces the risk of obesity later in life, and avoiding complementary foods until 4 months of age is also recommended. Starting at 2 years of age, approaches that combine changes in diet and physical activity are used. Obesity prevention interventions carried out in children’s educational institutions, including with the participation of the family, are most eff ective. Promising methods for correcting food stereotypes are the Mediterranean diet, reducing the consumption of sugary drinks and increasing the consumption of fruits, vegetables and foods rich in dietary fi ber, which has a positive eff ect on various health parameters.
Psychological barriers to climate-friendly food choices
Authors: Theron Elzarie , Hagen Sean
Published: November 2023

The food supply chain is a significant contributor to climate change. By following a climate-friendly diet, consumers have the potential to significantly reduce the effects of climate change. However, despite the growing awareness of the climate-friendly food options that are available, consumers still choose foods with a high carbon footprint. Following a survey design, this study aimed to determine the extent to which four psychological processes (denial, conflicting goals and aspirations, tokenism, and interpersonal influence) limited climate-friendly food choices in a sample of adult consumers residing in Gauteng, South Africa. Data were collected from 146 participants using the Climate-friendly Food Choices Scale and the Psychological Barriers Scale. Results indicated that, overall, the barriers were negatively associated with climate-friendly food choices. Regression analysis indicated that the four psychological barriers explained 10.6 % of the variance in climate-friendly food choices. Conflicting goals and aspirations and denial were identified as the two main psychological barriers to climatefriendly food choices. It is therefore essential to consider the psychological processes that could have a limiting effect on the adoption of climate-friendly food choices in our approach to encourage pro-environmental change.
PhDing while panicking in a Pandemic
Authors: Makama Refiloe , Peters Simone
Published: November 2023

The Covid-19 pandemic resulted in a global panic and the destabilisation of economic, and education systems resulting in a sense of anxiety and helplessness at a societal and individual level. We offer a reflection of the end of our PhD journey, that occurred concurrently with the beginning of the Covid-19 lockdown in South Africa. Thinking through an intersectional lens we draw parallels between our precarity as black women in higher education nearing the end of our PhD journey (s) and the unpredictability of life during the pandemic. While we recognise the incompatibility of life during a pandemic and PhDing (completing a PhD), we use this moment to map out how the precariousness in academia lends itself to a sense of anxiety and helplessness often to the death of scholarship. We attribute our panic while PhDing to the process of completing the thesis as well as the sense of insecurity we have observed and experienced within academia. We argue that the casualisation of young black women academics, lends itself to the reproduction of exclusionary practices in higher education.
Competencias laborales y su relación con la productividad laboral de los trabajadores del Banco de Crédito del Perú Agencia-Abancay
Authors: Caballero-Rodríguez Beltrán , Alarcón-Palomino Ivon Nieves
Published: November 2023

Knowing today how valuable it is to know work skills and productivity in organizations, the main objective of the research was to determine the relationship that exists between work skills and work productivity of the wor-kers of the Banco de Crédito del Perú Agencia - Abancay, the methodology used took place with a quantitative approach, basic type of research, descriptive-correlational level and non-experimental cross-sectional design. The study population was 35 workers from the Banco de Crédito del Perú Agencia Abancay. The sample of our re-search was census-based, therefore, the sample was the 35 workers of the BCP Abancay agency. The survey te-chnique was applied, with its questionnaire instrument. The results obtained at the time of verifying the contrast of the hypothesis using Spearman's Rho statistic, achieving as a result that there is a direct, positive and high level of correlation between the contrasting variables.
Boiling and Condensation in Two-Phase System Transients with Water Hammer
Authors: Milivojevic Sanja , Stevanovic Vladimir , M. Petrovic Milan , Ilic Milica
Published: November 2023

Water hammer in two-phase systems, induced by direct steam condensation on subcooled water or by separation of subcooled water column, results in the most intensive pipeline pressure surges. Amplitudes of pressure spikes along the course of these dangerous transients strongly depend on the condensation and evaporation rates. The present paper provides a literature overview of thermal-hydraulic models for the prediction of water hammer phenomenon in two-phase systems, together with an original mechanistic approach for the prediction of phase transition rates, based on the shape and size of vapor-liquid interfacial area and the phase transition potential expressed through vapor and liquid phase temperature difference. Available water hammer experimental conditions were numerically simulated with the new modeling approach. Driving parameters of boiling and condensation rates at the steam-water interfaces are evaluated, and a good agreement is shown between numerical results and experimental data of bulk two-phase flow parameters during water hammer transients.
Vogt-Koyanagi-Harada Disease: Current Diagnosis and Management
Authors: Goyal Anubhav , Shah Vineet , Anantharaman Giridhar , Gopalakrishnan Mahesh
Published: November 2023

Vogt-Koyanagi-Harada (VKH) disease is a rare granulomatous inflammatory disease that affects pigmented structures, such as eye, inner ear, meninges, skin, and hair. This disease is mainly a T1 lymphocyte-mediated aggression to melanocytes. The availability of new investigational methods has improved our knowledge of the pathogenesis, clinical approach, diagnosis, and management of VKH disease. The disease has an acute onset of bilateral blurred vision with hyperemia in the absence of prior ocular trauma or any previous intraocular surgery. The chronic phase comprises of ocular and integumentary system pigmentary changes. Ocular findings may be accompanied by meningismus, hearing impairment, and skin lesions in a variable proportion of patients. Prompt diagnosis with early, aggressive, and long-term treatment of high-dose corticosteroids ensures good visual outcomes. The aim of this chapter is to present the clinicopathology, classification, recent imaging, investigations, and management of VKH disease.
Bases of Mathematical Simulation of Modes Obtaining Ultrafine Powder by Laser Ablation of Metal Particles Vertically Falling under the Action of Gravity in an Inert Gas Medium
Authors: Ilyushchanka A.Ph.
Published: November 2023

The fundamentals of mathematical modeling of the modes of obtaining an ultrafine powder by metal particles laser ablation of vertically falling in an inert gas medium under the action of gravity, provided that these particles flow around the laminar flows of this gas and are outlined. Using the results of the research as an example, the practical possibility of using these foundations of mathematical modeling is shown when obtaining ultrafine powders with particles having a shape close to spherical by the proposed method of laser ablation from spherical titanium particles of a fraction of 45–63 μm falling vertically in an inert gas medium. It is recommended to use the developed foundations of mathematical modeling in the design and development of laser ablation-based technologies for obtaining ultrafine and nanosized powders, including those in demand in the additive manufacturing of powders.
New Potentials in Modeling the Nonlinear Dynamics of the Combined Motion of Structures with Liquid
Authors: Limarchenko Oleg
Published: November 2023

Nonlinear models of the combined motion of structures carrying liquid with a free surface for translational and rotational motion of the carrying structure were constructed based on the variational approach. Using some specific features this method was applied also for modeling structures with limited volumes of liquid for reservoirs of revolution. The obtained model is free from some restricting assumptions used by other authors and more convenient for numerical implementation. The performed study of the development of resonant processes enables considerable revision of the problem of steady resonant motion of structures with liquid and research of transient modes for translational and rotational motion of the carrying structure. Due to new potential in modeling different processes, we generalized the statement of the problem of parametric oscillations of reservoirs with liquid and found some new features of the system behavior. Some potentials for reduction of the effect of liquid mobility on the motion of the carrying structure by the algorithm of compensation of the liquid response on reservoir walls were studied too.
Iron Oxide Nanoparticles: A Mighty Pioneering Diagnostic Tool But Is It Really Safe for Carcinoma and Neurodegenerative Diseases?
Authors: Sandhiya V. , Elumalai Selvaraja , Dhunmati K. , Nalini C.N. , Mani Ganesh , Balakrishnan Senthilkumar , Uthumansha Ubaidulla
Published: November 2023

Iron oxide nanoparticles have been used in medicine for around 90 years, and this time has demonstrated their versatility, therapeutic efficacy, and safety. The primary constituents of iron oxide nanoparticles (IONs) are either magnetite (FeO Fe2O3) or maghemite (-Fe2O3). The most major clinical application of IONs is based on MRI. To detect cancers and age-related diseases, IONs are being used in medical diagnostic imaging. The two IONs with the best clinical repute are Resovist and Feridex IV. In addition to being used to detect cancers, IONs are also adapted as gastrointestinal negative contrast agents and as slow-release iron supplements to treat iron deficiency anemia. With IONs exposed to alternating magnetic fields, targeted imaging and thermal energy production are both feasible. Radiation therapy, immunotherapy, or chemotherapy be facilitated by the effects of heat. A growing number of IONs are being studied in therapeutic settings as nanotechnology develops swiftly. How IONs are used in biomedicine is determined by their interaction with the human immune system.
Peripartum Hysterectomy
Authors: Baki Şentürk Mehmet , Çam Çetin , Üstün Batuhan
Published: November 2023

Peripartum hysterectomy is a lifesaving surgical procedure that is performed during or immediately after childbirth. Although it is a rare event, it is associated with significant maternal morbidity and mortality. This chapter provides a comprehensive overview of the indications, techniques, and outcomes of peripartum hysterectomy. It also discusses the risk factors, prevention strategies, and management of complications associated with this procedure. The chapter is a valuable resource for obstetricians, gynecologists, and other healthcare professionals involved in the care of pregnant women. It provides evidence-based recommendations and practical guidance to help improve the outcomes of peripartum hysterectomy and ultimately save lives.
Spintronic Nano-Oscillators
Authors: Wang Shun , Yao Linrong , Jiang Sheng
Published: November 2023

Spintronic nano-oscillators represent a novel class of nonlinear auto-oscillators that effectively convert magnetization precession into a microwave voltage signal by means of spin torque exerted through an electric current. These nano-oscillators can be categorized as either spin-torque nano-oscillators (STNOs) or spin-Hall nano-oscillators (SHNOs), depending on the driving force involved, namely, spin-transfer torque or spin-orbit torque. The present chapter offers a comprehensive review of the fundamental aspects and recent advancements in spintronic nano-oscillators. Firstly, the discussion encompasses spin torques and magnetoresistive effects. Subsequently, the underlying principles and theoretical foundations of spintronic nano-oscillators are elucidated, encompassing the Landau-Lifshitz-Gilbert-Slonczewski (LLGS) equation and nonlinear auto-oscillation theory. Additionally, the chapter outlines the structures, characteristics, and synchronization phenomena exhibited by these oscillators. Lastly, prospective applications such as microwave communication, assisted magnetic recording, and neuromorphic computing are explored. This review is poised to stimulate research interest, particularly with regard to the commercialization of promising applications.
Recent Progress and Current Status of Photocatalytic NO Removal
Authors: Hailili Reshalaiti , Li Zelong , Lu Xu , Reyimu Xiaokaiti
Published: November 2023

Air pollution has become a globally prominent environmental problem in which nitrogen oxide (NOx, 95% NO and NO2) has been considered as one of the most serious harmful gaseous pollutants that can cause haze, photochemical smog, and acid rain. Exposure to NO (∼ppb) harms human health with a risk of respiratory and cardiopulmonary diseases. As such, much attention is focused on the throughout removal, effective control, and precise monitoring of NO, especially for those of NO with low concentration (∼ppb). Semiconductor-based photocatalysis is a practical approach for pollutant treatments, especially for low concentrations but highly toxic ones, for example, NO (∼ppb) removal in indoor and outdoor atmospheres. This work aims to introduce the main process, methods and summarize the critical scientific issues during the photocatalytic NO treatment and review the latest progress in semiconducting materials. This work also surveys the newly emerged photocatalysts such as metal oxides, Bi-based semiconductors, including Bi2O2CO3, BiOX (X = Cl, Br, and I), Bi-metal-based defective photocatalysts, and other Bi-based catalysts with well-defined surface/interface characters for the complete NO removal, specific conversion mechanisms and controlling the generation of the toxic intermediate (NO2) is highlighted. The challenges/bottlenecks of the practical applications in the field are also highlighted at the end.
Leptin and Obesity: Understanding the Impact on Dyslipidemia
Authors: Rangareddy Harish , Venkatapathappa Priyanka , Mandalaneni Kesava , Srinivasaiah Ashakiran , Bourne-Yearwood Katherine
Published: November 2023

Leptin, a hormone produced by fat cells, regulates energy balance and body weight by suppressing appetite and increasing energy expenditure. In obesity, there is often leptin resistance, reducing the hormone’s effects due to factors such as inflammation and changes in leptin receptors. This resistance leads to an increased risk of weight gain and obesity. Leptin therapy shows promise in treating obesity and related metabolic disorders, such as dyslipidemia and type 2 diabetes mellitus. It can lower body weight, improve insulin sensitivity, and reduce blood glucose and lipid levels. However, its effectiveness may be limited by the development of leptin resistance. Leptin also exhibits anti-inflammatory and cardiovascular protective effects, with potential therapeutic value for obesity-related conditions. Nevertheless, further research is necessary to comprehend leptin’s mechanisms and develop safe and effective therapies for these conditions, including those targeting dyslipidemia.
The Effect of Accounting Disclosure on Investment Decision-Making—A Case Study Sample of Investors in Companies Listed on Palestine Stock Exchange
Authors: Faza Mustafa , Badwan Nemer , Hamdan Montaser , Al-Khazaleh Suhaib
Published: November 2023

The main purpose of the current research is to focused on how accounting disclosure affects investment decisions. To achieve the main objective of this research, the researchers employed the methodology used in the study and used the questionnaire tool and Pearson correlation coefficient to ascertain how accounting disclosure affects investment decisions-making. Data from the study sample was gathered using the questionnaire approach, which was then distributed to a sample of investors in the firms listed on the Palestine Stock Exchange. Percentages and frequencies were used as statistical techniques in this study in order to determine how the study sample responded to the study\'s axes and fields and to describe the characteristics of the study sample. The Pearson correlation coefficient was also used to demonstrate the relationship between the independent and dependent variables. The current research reached several results, such as the contribution of accounting disclosure in providing future accounting information that is disclosed and that affects investment decisions in the Palestinian Stock Exchange and helps investors in making sound and correct decisions. The most important results of the study show that there is a significant relationship at a significant level (0.05) between accounting disclosure and the investment decisions of a sample of investors in companies listed on the Palestine Stock Exchange.
Excipient-Free Spray Drying of Bioactive Recombinant Proteins Produced in Plants
Authors: Reynisdóttir Natalía , Thor Ingvarsson Páll , María Einarsdóttir Ásta , Freyr Ingunnarson Arnór , Nagy Ildikó
Published: November 2023

Spray drying is an economical drying method for converting aqueous solutions into stable dry powders. This one-step continuous process generates a sustainable solution for long-term storage of various protein formulations. This study focuses on recombinant growth factors produced in a barley seed host. The retained bioactivity of the growth factor in the final solid form suggests that co-purified host components may have preserving effects throughout the optimized spray drying process. To identify the critical spray drying parameters, a customized response surface design of experiment was applied. The defined input spray drying parameters: feed flow rate, spray gas flow rate, and outlet temperature, as well as their interactions, were discovered to be the most critical in terms of product quality and yield. The best operating parameters were chosen after considering potential reduction in energy consumption of the process. Cell proliferation assay results, which show the bioactivity of the growth factors, reveal that the native host components seem to act as proper stabilizing agents that protect the fragile growth factors against various stresses during the drying procedure. This unique matrix composition therefore surpasses the time-consuming process optimization with excipients, allowing for a fully continuous process from purification to the final formulated powder.
Sustainable Management of Phosphorus in Agriculture for Environmental Conservation
Authors: Sharmin Hoque Tahsina , Sarkar Deepranjan , Datta Rahul , Golam Kibria Mohammad , Ullah Rafi , Ahmed Nazeer , Anwar Hossain Mohammad , Masood Asim , A. Anjum Naser
Published: November 2023

Phosphorus (P) is an essential macronutrient for plant growth and development. Although the P-concentration in soil is 1000 folds higher than in plants, it is rarely available for plant uptake due to low diffusion and high fixation rate in soil. Hence, plants experience P-deficiency in the absence of P-fertilization, which may cause approximately a 30–40% decrease in crop yield. This highlights the importance of using a large amount of phosphate fertilizers to meet crop demands. As P-fertilizer is derived from a nonrenewable and finite source of rock phosphate, this resource is decreasing over time. In addition, farmers are applying P-fertilizers randomly without considering the soil stock, which leads to the loss of P-resources. The low P-use-efficiency (PUE) of plants in the field condition (15–20%) highlights that most of the soil-applied P remains unavailable to plants, and excess P causes ground and surface water contamination (i.e., eutrophication) through leaching and runoff, which ultimately results in environmental pollution. Therefore, it is crucial to apply P-fertilizers considering the soil test value and PUE to protect the environment from contamination and sustainable management of P-resources. This chapter mainly focuses on the sustainable management of P in agricultural fields for environmental conservation.
Analysis of a Fundamental Procedure for Solving the Inverse Heat Conduction Problem Applied to Simple Systems
Authors: Sergio Téllez-Martínez Jorge , Zulma Sánchez-Hernández Miriam , Janeth Vega-Flores María , Alberto Pintor-Estrada Abel , Enrique Alva-Medrano Hugo , David Herrera-Sandoval Nicolás
Published: November 2023

Heat transfer phenomena develop in various natural and artificially created processes. Fundamental laws of physics allow the transfer mechanisms to be classified; however, describing the phenomena is relatively complex, even if the analysis is limited to conduction. In particular, to determine the temperature distribution in a solid body, the definition of the boundary conditions that perturb it is required. Such conditions mathematically model a fluid’s hydrodynamic and thermodynamic behavior, and when the temperature differences are significantly high, the flow by radiation. It is then complex to define the functions of the thermal boundary conditions and solve the well-posed problem. Naturally, nonlinear system results and applying numerical methods are constant in the analysis. However, a unique solution for the thermal field in a solid does ensure. Alternatively, the scheme of the discretization of the system allows us to propose that through the knowledge of a fraction of the thermal field, the boundary condition is quantified independently of its nature. Such a procedure is called inverse analysis and has the characteristic of not satisfying the single solution criterion. However, some cases of interest can treat, and the estimate is guaranteed to be highly accurate.
Application of Internet of Things (IoT) in Biomedicine: Challenges and Future Directions
Authors: Fuior Robert , Sălceanu Alexandru , Luca Cătălina , Corciovă Călin
Published: November 2023

The Internet of Things (IoT) is currently rapidly being incorporated into many fields, but there are still some fields, such as healthcare, where IoT adoption is much slower. Medical IoT refers to a range of medical devices and people that rely on wireless communication to enable healthcare data exchange, remote monitoring, and patient rehabilitation for a better quality of life for the patient. Medical IoT can provide better medical care and rehabilitation services under the careful supervision of the physician, resulting in more cost-effective systems for hospitals as well as for the patient. Due to the regulatory, ethical, and technological challenges of biomedical hardware, the growth of medical IoT is still inhibited. The chapter provides an overview of the various technologies and protocols used for the Internet of Medical Things (IoT), with an overview of the current technologies, applications, and challenges.