bluuebunny/crossref_metadata_2025 huggingface dataset:
Report of the 6th ACM SIGSPATIAL International Workshop on Geospatial Humanities (GeoHumanities 2022)
Authors: Moncla Ludovic , Martins Bruno , McDonough Katherine
Published: November 2023

The field of Geospatial Humanities addresses the use of geographic information systems and other spatial technologies in humanities research, looking to address questions related to space and place. The field is constantly evolving, and currently it is posing very interesting challenges relating, for example, to the identification and analysis of real, vague, and imaginary space in humanities sources like archival manuscripts, maps, encyclopedias, newspapers, correspondence collections, and more. These kinds of documents pose new challenges for identifying and analyzing spatial information, and a strong emphasis is being put on new methodologies that leverage the standard tools from geographic information systems, as well as more advanced methods (e.g., based on machine learning) such as text- and image-based geographical analysis, this way combining GIS, NLP, Deep Mapping, Computer Vision, and Qualitative Spatial Representation, among others.
GeoKG'2022 Workshop Report: The 1st ACM SIGSPATIAL International Workshop on Geospatial Knowledge Graphs
Authors: Zhu Rui , Janowicz Krzysztof , Thakur Gautam , Ma Xiaogang , Young Ellie , Mai Gengchen
Published: November 2023

The topic of knowledge graphs (KGs) has recently attracted extensive attention in both industry and academia. Knowledge graphs are a new paradigm for representing, retrieving, integrating, and reasoning data from highly heterogeneous and multimodal sources. For example, international conferences, such as the Knowledge Graph Conference, have emerged in the past years, not to mention the increasing number of specialized workshops on KGs co-located with major computer science conferences, including Knowledge Graph Workshop at KDD 2021, Workshop for Deep Learning in Knowledge Graphs at ISWC 2021, Workshop on Knowledge Graph Construction at ESWC 2021, to name but a few. Also, the number of KGs-related papers accepted at these major conferences, including SIGSPATIAL, is rapidly increasing. Meanwhile, we also witness the increasing popularity of knowledge graph technologies in geography, geoinformatics, and GIScience domains. There are growing numbers of knowledge graph-related manuscripts accepted to the top geospatial-related venues, such as the International Journal of Geographical Information Science, Transactions in GIS, the International Journal of Applied Earth Observation and Geoinformation, and so on. Transactions in GIS also held two special issues about knowledge graphs: 1) Symbolic and Subsymbolic GeoAI: Geospatial Knowledge Graphs and Spatially Explicit Machine Learning [4], and 2) Knowledge-based GIS (K-GIS): Theories, Techniques and Applications. In addition, government agencies, industries, and non-governmental organizations (NGOs) are also lifting resources on topics of exploring KGs to build up interdisciplinary science and applications. One example is NSF's Accelerate Convergence Program, which promotes the idea of building an Open Knowledge Network to harness the data revolution. Funded by this program, the KnowWhereGraph is presently among the largest geo-enabled knowledge graphs, which integrates 28 different data layers at the intersection between humans and their environment [2].
Nutrient Uptake and Efficiencies of Orange-Fleshed Sweet Potato (Ipomoea batatas L.) Varieties under Different Rates of Nitrogen and Phosphorus Fertilizers
Authors: Lemma Miheret Hendebo , Mohammed Ali , Gurmu Fekadu , Beshir Hussien Mohammed
Published: November 2023

Sweet potatoes serve as a staple food and animal feed in Africa and serve as a source of raw materials for the food, feed, pharmaceutical, cosmetic, chemical, and energy industries. The yield of orange-fleshed sweet potatoes is increased when nitrogen (N) and phosphorus (P) are added to low-fertility soils. The objective of this study was to evaluate the nutrient uptake and use efficiency of orange-fleshed sweet potato varieties under applied N and P. The experiment was conducted for two growing seasons (2019 and 2020) under rain-fed conditions in the field. The study included five orange-fleshed sweet potato varieties (Kulfo, Kabode, Alamura, Dilla, and NASPOT-12), three N levels (0, 23, and 46 kg·N·ha−1), and two levels of P (0 and 46 kg P2O5·ha−1) fertilizers designed in 5 × 3 × 2 with α-lattice design in factorial arrangement using 3 replications. The interaction effect of variety, N, and P fertilizers affected nutrient uptake, physiological efficiency, and agronomic efficiency of sweet potatoes. NASPOT-12 was the better variety in nutrient uptake but poor in apparent recovery at all levels of N and P. The highest nutrient uptake, agronomic efficiency, and physiological efficiency were observed on NASPOT-12 when subjected to 23 kg N·ha−1 and 46 kg P2O5·ha−1. Overall, NASPOT-12 with 23 kg·N·ha−1 and 46 kg P2O5·ha−1 could be recommended for its high nutrient uptake, agronomic, and physiological efficiencies.
Prevalence and Risk Factors of Postprocedure Depression in Patients with Atrial Fibrillation after Radiofrequency Ablation
Authors: Du Mingli , Cheng Tieniu , Ye Yutong , Wei Yong
Published: November 2023

Background. Recent studies have shown a bidirectional relationship between atrial fibrillation (AF) and psychological depression. However, little is known about the prevalence of postprocedure depression (PPD) in patients with AF at the time of radiofrequency (RF) ablation. Objective. To describe the prevalence and identify risk factors for PPD. Methods. This was a prospective cohort study, including 428 AF patients who were willing to undergo the first catheter ablation in our hospital from 1st April to 30th December 2019. The primary outcome was PPD, which was determined by Hospital Anxiety and Depression Scale-Depression. Results. The prevalence of PPD was 16.8% (72/428) in our cohort, without difference between men (16.0%, 41/256) and women (18.0%, 31/172) (P = 0.586) but with a great difference among different age groups (P = 0.016). On the univariable binary logistic regression analysis, age, a history of coronary heart disease, Observer’s Assessment of Alertness/Sedation (OAA/S) score when ablating at the specific position, and OAA/S score when pulling out the catheter sheath were associated with PPD. Subsequent multivariable logistic regression analysis indicated only age (OR 0.96, 95% CI: 0.94–0.99,

P
<
 
0.01

) and OAA/S score when ablating at the specific position (OR 0.58, 95% CI: 0.39–0.88, P = 0.01) were independently associated with PPD. Conclusion. PPD is common in patients with AF after RF ablation. Younger age and lower OAA/S score when ablating at the specific position are its most significant risk factors. Intensive management of sedation may be of great importance for reducing PPD. This trial is registered with the Chinese Clinical Trial Registry (ChiCTR2200057810).
Nanostructured Lipid Carriers for Improved Delivery of Therapeutics via the Oral Route
Authors: Mahor Alok Kumar , Singh Prem Prakash , Gupta Rishikesh , Bhardwaj Peeyush , Rathore Priyanka , Kishore Ankita , Goyal Rohit , Sharma Neeraj , Verma Jyoti , Rosenholm Jessica M. , Bansal Kuldeep K.
Published: November 2023

Drug delivery via the oral route has always been challenging for poorly soluble drugs. Acid-induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the primary hiccups for effective oral delivery of medications. With the advent of nanotechnology, nanostructured lipid carriers (NLCs) have emerged as a promising delivery carrier that can circumvent gastrointestinal tract (GIT) barriers hindering the solubility and bioavailability of such drugs. These NLCs can efficiently transport drug moieties across intestinal membranes shielding medications from intestinal pH and enzymatic degradation. Because they are composed of lipidic materials, they can be easily absorbed or taken up by various pathways such as transcellular absorption, paracellular transport, and M-cell uptake. Such mechanisms not only improve the absorption and solubility of drugs but also augment bioavailability and residence time and may bypass first-pass metabolism. This review explores the diverse applications of nanostructured lipid carriers (NLCs) in oral drug delivery for various medical conditions, shedding light on their current regulatory status, including FDA-approved options and those in pre/clinical stages. The review also features patented NLC formulations. It provides valuable insights into how NLCs can be harnessed for effective oral drug delivery and outlines recent advancements in optimizing their performance to tackle gastrointestinal barriers, thus opening new possibilities for NLCs in future pharmaceutical applications.
Sestrin2 Regulates Endoplasmic Reticulum Stress-Dependent Ferroptosis to Engage Pulmonary Fibrosis by Nuclear Factor Erythroid 2-Related Factor 2/Activating Transcription Factor 4 (NRF2/ATF4)
Authors: Dong Zhaoxing , Li Ting , Wang Cenli , Zhou Yong , Tong Zhongkai , Du Xuekui
Published: November 2023

Pulmonary fibrosis (PF) can lead to chronic inflammation, the destruction of alveoli and irreversible lung damage. Sestrin2 is a highly protective stress-inducible protein that is involved in the cell response to various stress factors and the regulation of homeostasis and has a certain protective effect against PF. In this study, TGF-β1 was used to establish a PF cell model. Bleomycin was used to induce PF in mice, and the expression levels of related proteins were detected by western blotting. The levels of the inflammatory cytokine, TNF-α, IL-6, and IL-1β were detected by enzyme-linked immunosorbent assays. Immunoprecipitation was used to verify the interaction between ATF4 and NRF2 and between Sestrin2 and NRF2 to explore the specific mechanism by which Sestrin2 affects PF. The results showed that Sestrin2 inhibited fibroblast-to-myofibroblast transition (FMT), improved inflammation, promoted cell proliferation, and alleviated PF. Activating transcription factor 4/nuclear factor erythroid 2-related factor 2 (NRF2/ATF4) signaling pathway activation could alleviate endoplasmic reticulum stress, inhibit ferroptosis and FMT, and reduce reactive oxygen species levels, thereby alleviating PF. Overexpression of ATF4 and the addition of a ferroptosis inducer reversed Sestrin2-mediated alleviation of PF. In conclusion, Sestrin2 alleviates PF and endoplasmic reticulum stress-dependent ferroptosis through the NRF2/ATF4 pathway.
A Prospective Study of Clinical Features of Anterior Uveitis in Taiwan
Authors: Chiang Wei-Yu , Chen Shih-Chou , Sheu Shwu-Jiuan , Kuo Hsi-Kung
Published: November 2023

In this study, we reported the patterns, epidemiology, and clinical features of anterior uveitis (AU) in Taiwan, an area of Eastern Asia. This prospective, cross‐sectional case series study was performed to identify patients with AU at two tertiary medical centers (Kaohsiung Chang Gung Memorial Hospital and Kaohsiung Veterans General Hospital) located at the southern Taiwan between December 1, 2018, and March 31, 2020. The clinical diagnoses, ocular presentations, and laboratory data, including the results of the aqueous polymerase chain reaction tests, were investigated in these patients. A total of 112 patients, with a mean age of 48.9 years, were included. Most patients (87.5%) presented with unilateral eye disease, with 30 cases of ocular hypertension at the first presentation (27%). The most common clinical diagnoses were idiopathic AU (37.5%), human leukocyte antigen (HLA)‐B27‐associated acute AU (25.0%), and herpetic AU (18.8%). Among patients with herpetic AU, cytomegalovirus (CMV) was the most common pathogen (17/21, 81%). Compared to HLA‐B27‐associated acute AU, CMV‐related AU was mostly observed in patients that were older in age, exhibited higher intraocular pressure, more keratic precipitates, greater iris atrophy, and more pseudophakia, but was least reported in those with posterior synechiae. This prospective study identified the pattern and clinical features of AU in southern Taiwan.
SUV39H1 Ablation Enhances Long-term CAR T Function in Solid Tumors
Authors: López-Cobo Sheila , Fuentealba Jaime R. , Gueguen Paul , Bonté Pierre-Emmanuel , Tsalkitzi Kyriaki , Chacón Irena , Glauzy Salomé , Bohineust Armelle , Biquand Ariane , Silva Lisseth , Gouveia Zelia , Goudot Christel , Perez Franck , Saitakis Michael , Amigorena Sebastian
Published: November 2023

Failure of adoptive T-cell therapies in patients with cancer is linked to limited T-cell expansion and persistence, even in memory-prone 41BB-(BBz)–based chimeric antigen receptor (CAR) T cells. We show here that BBz-CAR T-cell stem/memory differentiation and persistence can be enhanced through epigenetic manipulation of the histone 3 lysine 9 trimethylation (H3K9me3) pathway. Inactivation of the H3K9 trimethyltransferase SUV39H1 enhances BBz-CAR T cell long-term persistence, protecting mice against tumor relapses and rechallenges in lung and disseminated solid tumor models up to several months after CAR T-cell infusion. Single-cell transcriptomic (single-cell RNA sequencing) and chromatin opening (single-cell assay for transposase accessible chromatin) analyses of tumor-infiltrating CAR T cells show early reprogramming into self-renewing, stemlike populations with decreased expression of dysfunction genes in all T-cell subpopulations. Therefore, epigenetic manipulation of H3K9 methylation by SUV39H1 optimizes the long-term functional persistence of BBz-CAR T cells, limiting relapses, and providing protection against tumor rechallenges.

Significance:

Limited CAR T-cell expansion and persistence hinders therapeutic responses in solid cancer patients. We show that targeting SUV39H1 histone methyltransferase enhances 41BB-based CAR T-cell long-term protection against tumor relapses and rechallenges by increasing stemness/memory differentiation. This opens a safe path to enhancing adoptive cell therapies for solid tumors.

See related article by Jain et al., p. 142.

This article is featured in Selected Articles from This Issue, p. 5
Supplementary Table 3 from Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
Authors: Tang Wei , Zhang Flora , Byun Jung S. , Dorsey Tiffany H. , Yfantis Harris G. , Ajao Anuoluwapo , Liu Huaitian , Pichardo Margaret S. , Pichardo Catherine M. , Harris Alexandra R. , Yang Xiaohong R. , Figueroa Jonine D. , Sayed Shahin , Makokha Francis W. , Ambs Stefan
Published: November 2023

Differentially expressed genes and pathway enrichment analysis comparing the 3 patient groups, EA, AA and Kenyan.
Data from Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
Authors: Tang Wei , Zhang Flora , Byun Jung S. , Dorsey Tiffany H. , Yfantis Harris G. , Ajao Anuoluwapo , Liu Huaitian , Pichardo Margaret S. , Pichardo Catherine M. , Harris Alexandra R. , Yang Xiaohong R. , Figueroa Jonine D. , Sayed Shahin , Makokha Francis W. , Ambs Stefan
Published: November 2023

Abstract
Women of African descent have the highest breast cancer mortality in the United States and are more likely than women from other population groups to develop an aggressive disease. It remains uncertain to what extent breast cancer in Africa is reminiscent of breast cancer in African American or European American patients. Here, we performed whole-exome sequencing of genomic DNA from 191 breast tumor and non-cancerous adjacent tissue pairs obtained from 97 African American, 69 European American, 2 Asian American, and 23 Kenyan patients. Our analysis of the sequencing data revealed an elevated tumor mutational burden in both Kenyan and African American patients, when compared with European American patients. TP53 mutations were most prevalent, particularly in African American patients, followed by PIK3CA mutations, which showed similar frequencies in European American, African American, and the Kenyan patients. Mutations targeting TBX3 were confined to European Americans and those targeting the FBXW7 tumor suppressor to African American patients whereas mutations in the ARID1A gene that are known to confer resistance to endocrine therapy were distinctively enriched among Kenyan patients. A Kyoto Encyclopedia of Genes and Genomes pathway analysis could link FBXW7 mutations to an increased mitochondrial oxidative phosphorylation capacity in tumors carrying these mutations. Finally, Catalogue of Somatic Mutations in Cancer (COSMIC) mutational signatures in tumors correlated with the occurrence of driver mutations, immune cell profiles, and neighborhood deprivation with associations ranging from being mostly modest to occasionally robust. To conclude, we found mutational profiles that were different between these patient groups. The differences concentrated among genes with low mutation frequencies in breast cancer.
Significance:
The study describes differences in tumor mutational profiles between African American, European American, and Kenyan breast cancer patients. It also investigates how these profiles may relate to the tumor immune environment and the neighborhood environment in which the patients had residence. Finally, it describes an overrepresentation of ARID1A gene mutations in breast tumors of the Kenyan patients.
New methodologies for the digital age? How methods (re-)organize research using social media data
Authors: Fan Yangliu , Lehmann Sune , Blok Anders
Published: November 2023

As “big and broad” social media data continues to expand and become a more prevalent source for research, much remains to be understood about its epistemological and methodological implications. Drawing on an original data set of 12,732 research articles using social media data, we employ a novel dictionary-based approach to map the use of methods. Specifically, our approach draws on a combination of manual coding and embedding-enhanced query expansion. We cluster journals in groups of densely connected research communities to investigate how heterogeneous these groups are in terms of the methods used. First, our results indicate that research in this domain is largely organized by methods. Some communities tend to have a monomethod culture, and others combine methods in novel ways. Comparing practices across communities, we observe that computational methods have penetrated many research areas but not the research space surrounding ethnography. Second, we identify two core axes of variation—social sciences vs. computer science and methodological individualism vs. relationalism—that organize the domain as a whole, suggesting new methodological divisions and debates.
Retracted articles use less free and open-source software and cite it worse
Authors: Schindler David , Yan Erjia , Spors Sascha , Krüger Frank
Published: November 2023

As an essential mechanism of scientific self-correction, articles are retracted for many reasons, including errors in processing data and computation of results. In today’s data-driven science, the validity of research data and results significantly depends on the software employed. We investigate the relationship between software usage and research validity, eventually leading to article retraction, by analyzing software mentioned across 1,924 retraction notices and 3,271 retracted articles. We systematically compare software mentions and related information with control articles sampled by coarsened exact matching by recognizing publication year, scientific domain, and journal rank. We identify article retractions caused by software errors or misuse and find that retracted articles use less free and open-source software, hampering reproducible research and quality control. Moreover, such differences are also present concerning software citation, where retracted articles less frequently follow software citation guidelines regarding free and open-source software.
Causation Bridges the Two Times
Authors: Andersen Holly K.
Published: November 2023

The two-times problem, where time as experienced seems to have distinctive features different than those found in fundamental physics, appears to be more intractable than necessary, I argue, because the two times are marked out from the positions furthest apart: neuroscience and physics. I offer causation as exactly the kind of bridge between these two times that authors like Buonomano and Rovelli (forthcoming) are seeking. It is a historical contingency from philosophical discussions around phenomenology, and a methodological artefact from neuroscience, that most studies of temporal features of experience require subjects to be sufficiently still that their engagement with affordances in the environment can be at best tested in artificial and highly constrained ways. Physics does not offer an account of causation, but accounts of causation are tied to or grounded in physics in ways that can be clearly delineated. Causation then serves as a bridge that coordinates time as experienced, via interaction with affordances in the environment, with time in physics as it constrains causal relationships. I conclude by showing how an information-theoretic account of causation fits neatly into and extends the information gathering and utilizing system (IGUS) of Gruber et al. (Front. Psychol., 13, 718505).
The Dynamics of Mobility and Immobility in the Face of Danger: Polish Jewish Migrations during the 1930s from Below
Authors: Zalc Claire , Perdoncin Anton , Escaich Gabrielle
Published: November 2023

This article draws on the exhaustive reconstruction of the transnational migration trajectories of Jewish and Catholic inhabitants from a small Polish town during the interwar period to explore the social and relational dimensions of migration. Implementing a mesoscopic analytical scale, the authors quantitatively and qualitatively analyse dense and varied historical material. They examine the relationship between relational configurations of mobility and immobility, as well as the increasing dangers faced by Polish Jews in the decade leading up to the war and the destruction of their communities. This change of scale gauges the specific impact of the temporal context – namely rising peril and anti-Semitic violence against Polish Jews in the 1930s – on the dynamics of mobility. It also leads to a better understanding of the importance and nature of obstacles to migration. By doing so, the authors advocate for a social history of migrations and connections that considers emigration as the product of relational configurations in societies of origin. Moreover, they show that ties, so often described as resources in analyses of migration, can also be burdens when it comes to escaping persecution.
Multiple jeopardy, national wealth and perceived discrimination: Subjective health of intersecting minority groups across 28 countries
Authors: Vauclair Christin-Melanie , Rudnev Maksim
Published: November 2023

Objective: Belonging to social minority groups is detrimental for health outcomes, yet it is still unclear how multiple social minority statuses combine in their effect on health and whether perceived discrimination explains this link. Moreover, the moderating role of the societal context on the multiple social minority status-health link has never been tested. The current study employs a comprehensive conceptual framework to better understand the patterns of association between health outcomes and multiple social minority statuses. Methods and measures: Using data from the European Social Survey (N = 53,161 from 28 countries) and multi-level structural equation modelling, the study examines whether older age, female gender and ethnic minority status have additive, exacerbation or inurement effects on subjective health, whether perceived discrimination mediates these relations, and whether national wealth moderates the associations. Results: Old age and female gender, but not ethnicity, were related to adverse health outcomes, especially in poorer countries. Belonging to two, but not three, social minority groups exacerbated health outcomes. Perceived discrimination explained some of the (multiple) social minority status-health links, whereas an ethnicity-related health risk was fully mediated by perceived discrimination. Conclusion: Supporting the idea of intersectionality, different combinations of social minority statuses differ in health outcomes as well as the underlying mechanisms.
Novel Strategies for Angiogenesis in Tissue Injury: Therapeutic Effects of iPSCs-Derived Exosomes
Authors: Zhang Jiaxin , Shi Maoning , Wang Jing , Li Fei , Du Chenxu , Su Gang , Xie Xiaodong , Li Shiweng
Published: November 2023

Regeneration after tissue injury is a dynamic and complex process, and angiogenesis is necessary for normal physiological activities and tissue repair. Induced pluripotent stem cells are a new approach in regenerative medicine, which provides good model for the study of difficult-to-obtain human tissues, patient-specific therapy, and tissue repair. As an innovative cell-free therapeutic strategy, the main advantages of the treatment of induced pluripotent stem cells (iPSCs)-derived exosomes are low in tumorigenicity and immunogenicity, which become an important pathway for tissue injury. This review focuses on the mechanism of the angiogenic effect of iPSCs-derived exosomes on wound repair in tissue injury and their potential therapeutic targets, with a view to providing a theoretical basis for the use of iPSCs-derived exosomes in clinical therapy.
The God of Virginia Theological Seminary, 1823–1871: Retracing a Tradition of Theological Liberalism and White Supremacy
Authors: Poore Christopher
Published: November 2023

In 1823, not only did a group of Episcopalians choose to found Virginia Theological Seminary. They also decided that this seminary would help keep human beings in bondage. Such an incredible decision begs the question, “What God were the seminary founders worshipping?” This essay aims to reconstruct the doctrine of God as it was taught at Virginia Seminary by turning to an examination of the seminary’s central dogmatic textbook, An Exposition of the Thirty-Nine Articles by Bishop Gilbert Burnet (1643–1715). While theologies of enslavement and white supremacy can be enunciated in many different keys, Burnet’s doctrine of God allowed white supremacy to flourish through a series of apparently liberal and enlightened methodological moves, chief among which was the downgrading of scripture’s authority and the elevation of human experience. By wrestling with Burnet’s legacy, this essay explores the reparative potential of dogmatic theology.
Work-related factors and the risk of common mental disorder 1 year later: A prospective cohort study among junior doctors
Authors: Petrie Katherine , Gayed Aimee , Spittal Matthew J , Glozier Nicholas , Shand Fiona , Harvey Samuel B
Published: November 2023

Objective:

This study investigated the relationship between work-related factors at baseline and the risk of common mental disorder at 12 month follow-up among a cohort of junior doctors.

Method:

The data comprised the junior doctor respondents from two annual waves of the ‘Medicine in Australia: Balancing Employment and Life’ (MABEL) survey, a national longitudinal cohort of Australian doctors. Individual and work-related risk factors were assessed at baseline and the mental health outcome of caseness of common mental disorder (CMD) was assessed using the 6-item Kessler Psychological Distress Scale at 12-month follow-up. Unadjusted and adjusted logistic regressions were conducted to estimate the association between each baseline variable and the likelihood of CMD caseness at follow-up 1 year later.

Results:

Among 383 junior doctors, 24 (6%) had CMD 1 year later. Five work-related baseline variables were significantly associated with a higher likelihood of CMD 1 year later in adjusted models; lack of social support in work location (odds ratios (OR) = 6.11; 95% confidence intervals (CI) = [2.52, 14.81]), work-life imbalance (OR = 4.50; 95% CI = [1.31, 15.46]), poor peer support network in the workplace (OR = 2.61; 95% CI = [1.08, 6.27]), perceptions of patient expectations (OR = 2.46; 95% CI = [1.06, 5.71]) and total weekly work hours (OR 1.04; 95% CI = [1.01, 1.07]; p = 0.002)in models adjusting for gender.

Conclusion:

These results identify key modifiable work-related factors that are associated with junior doctors’ future mental health. Our findings suggest the need for a greater focus upon interpersonal factors and work-life balance in multi-level interventions while continuing to address workplace and system-level factors to prevent future mental disorder in junior doctors.
The Socioecological Psychology of Financial Debts: The Role of Residential Mobility
Authors: Oishi Shigehiro , Komiya Asuka , Koo Minkyung , Cha Youngjae , Kothari Radhika
Published: November 2023

We examined individual, regional, and cultural differences in household debts and identified residential mobility as a key socioecological variable at multiple levels of analysis. Study 1 found that American households’ debt rates were higher than Japanese debt rates. Across 76 countries, household debts were higher in residentially mobile countries than those in residentially stable ones (Study 2). Next, across 144 U.S. cities, residents of residentially mobile cities had more credit card debts than those of residentially stable cities (Study 3). We further replicated the international and U.S. findings across 366 districts in India (Study 4). Study 5 found that American participants were more residentially mobile and more willing to borrow than Japanese participants, and the willingness to borrow was partly explained by the personal history of residential mobility. Study 6 found that residentially mobile individuals felt less indebtedness/gratitude than residentially stable individuals; the study also found how indebtedness/gratitude impacted individuals’ credit card debts and willingness to borrow.
Typography Talks: Influencing Vintage Anemoia and Product Safety Perceptions with Vintage Typography
Authors: Kulczynski Alicia , Hook Margurite
Published: November 2023

Drawing from the concept of anemoia, the authors propose a new typology of nostalgia called vintage anemoia. Vintage anemoia encompasses consumers’ positive and nostalgic response to vintage cues, regardless of specific historical periods or individual lived experiences. Through a series of seven studies, the authors demonstrate that vintage typography, by evoking feelings of vintage anemoia, can enhance consumer perceptions of product safety. This effect has positive downstream consequences on key marketing outcomes, including brand attitude, purchase intention, and willingness to pay. Furthermore, the effect of vintage anemoia on product safety perceptions remains unaffected by whether product safety information indicates that a product is safe or unsafe. However, the effect diminishes when an explicit indexical cue (year of establishment) is utilized or when promoting futuristic products. The findings contribute to the existing body of knowledge in marketing and provide insights for marketers on leveraging vintage typography as a strategic tool for creating emotional connections with consumers and enhancing perceptions of product safety.
Nurses’ Perceptions Towards Resuscitated Patients: A Qualitative Study
Authors: Zali Mahnaz , Rahmani Azad , Powers Kelly , Hassankhani Hadi , Namdar-Areshtanab Hossein , Gilani Neda , Dadashzadeh Abbas
Published: November 2023

Nurses’ perceptions of resuscitated patients may affect their care, and this has not been investigated in previous literature. The aim of this study was to explore nurses’ perceptions towards resuscitated patients. In this descriptive-qualitative study seventeen clinical nurses participated using purposive sampling. In-depth, semi-structured interviews were conducted and data were analyzed by conventional content analysis. Four main categories emerged: Injured, undervalued, problematic, and destroyer of resources. Participants considered resuscitated patients to have multiple physical injuries, which are an important source of legal problems and workplace violence, and they believed that these patients will eventually die. Resuscitated patients are considered forgotten and educational cases. Iranian nurses have a strong negative perception towards resuscitated patients. Improving the quality of cardiopulmonary resuscitation, improving the knowledge and skills of personnel in performing resuscitation, and supporting managers and doctors to nurses in the post-resuscitation period can change the attitude of nurses and improve post-resuscitation care.
Factors Affecting Death Anxiety in Patients Undergoing Open Heart Surgery: A Cross-Sectional Study
Authors: Dağcan Şahin Necibe , Gürol Arslan Gülşah , Özbek Dilara
Published: November 2023

After the operation, death anxiety of patients is affected by many factors. This study aims to investigate the factors affecting death anxiety of patients undergoing open heart surgery. A descriptive, cross-sectional study. Data were collected using the ‘Introductory Information Form,’ the 'Templer’s Death Anxiety Scale,’ and the ‘Spiritual Well-being Scale.’ This study was conducted with 313 intensive care patients. The mean scores of the patients on the “Death Anxiety Scale” were moderate (7.96 (4.28)). According to the study findings, age, gender, length of stay in the intensive care unit, and spiritual well-being were found to be important predictors of death anxiety (F (4,308) = 16.149, p < .001). Considering gender differences in nursing care, it is thought that the intensive care period will be shortened, the level of spiritual well-being will increase and death anxiety will decrease.
What Do Correctional Leaders Think About Faith-Based Programs? Results From a National Survey
Authors: Duwe Grant , Johnson Byron R. , Hallett Michael
Published: November 2023

While religious programs and services have long been a staple of the American prison experience, existing research has yet to examine how correctional administrators perceive their importance and effectiveness. Of the 50 states invited to participate in the survey, most of the 27 respondents reported that faith-based programming provides a critically important resource that yields successful outcomes and positively influences prison culture. Nearly half indicated that interest in programming exceeds the resources available, while two-thirds reported that programming access should be expanded. The vast majority cited a lack of physical space and security staff as barriers to increased programming access.
The Association of Autistic Traits on Cognitive Emotion Regulation Strategies in a Non-clinical Sample
Authors: Nagase Kai
Published: November 2023

Individuals with high autistic traits have difficulty in regulating their negative emotions. However, few studies clarify the relationship between autistic traits and cognitive emotion regulation strategies. This study examined the association between adaptive and maladaptive strategies in cognitive emotion regulation and autistic traits using a non-clinical sample. Two hundred and thirty-four participants completed the Japanese version of the Social Responsiveness Scale-2 (Adult Self-Report version) and the Japanese version of the Cognitive Emotion Regulation Questionnaire. The results showed that autistic traits were negatively associated with the use of adaptive subordinate strategies for cognitive emotion regulation. By contrast, autistic traits were positively associated with the use of maladaptive subordinate strategies of cognitive emotion regulation. The cognitive and emotional characteristics of autism spectrum disorder, such as perspective taking and executive function, contextualize these results. These findings can help guide not only our understanding of the relationship between autistic traits and cognitive emotion regulation but also develop interventions aimed at facilitating the use of adaptive cognitive emotion regulation strategies and preventing the use of maladapted strategies in individuals with high autistic traits.
Exposures to Bleach, Peroxide, Disinfectants, Antimalarials, and Ivermectin Reported to the California Poison Control System Before and During the COVID-19 Pandemic, 2015-2021
Authors: Ghai Alice , Sabour Emily , Salonga Raeann , Ho Raymond , Apollonio Dorie E.
Published: November 2023

Objectives:

The COVID-19 pandemic led to widespread fear of infection, with many people expanding their use of cleaning products and trying unproven prevention and treatment strategies. We described shifts in reported exposures related to COVID-19 home interventions.

Methods:

This study considered suspected toxicity exposures involving household cleaning products (bleach, peroxide, disinfectants), antimalarials (hydroxychloroquine and chloroquine), and ivermectin reported to the California Poison Control System from 2015 through 2021 and assessed trends in exposures by using interrupted time-series analyses.

Results:

We found a significant increase in exposures reported to the California Poison Control System related to household cleaning products and ivermectin during the COVID-19 pandemic. As of January 1, 2015, the baseline level of reported exposures to household cleaning products was 707.33 per month and was declining at a rate of 1.71 (95% CI, –2.87 to –0.56) per month through February 29, 2020. In March 2020, an increase of 466.57 (95% CI, 328.08-605.07) reported exposures above baseline occurred, after which exposures to cleaning products decreased at a rate of 23.40 (95% CI, –32.48 to –14.32) per month. The number of reported exposures to antimalarials did not change significantly before or during the pandemic. The number of reported ivermectin exposures before December 2020 was initially stable at 14.50 per month and then increased by 2.05 per month through December 2021.

Conclusions:

Our observations suggest that while some dangerous home prevention and treatment efforts resolve over time, further interventions may be needed to reduce the public health effects related to attempts to self-treat COVID-19 with ivermectin.
Trust the Process: A Scalable Model for UX Pedagogy
Authors: Rose Emma J. , Turner Heather N.
Published: November 2023

While user experience (UX) and technical and professional communication (TPC) are intertwined, how UX is taught in TPC is highly variable. In this article, we report data from a study with TPC instructors who teach UX to identify patterns in approaches to teaching UX. We provide background on UX pedagogy, share methods including collecting data from a questionnaire and interviews and conducting qualitative analysis. The findings map teaching activities onto the design process and show patterns and commonalities. We conclude by proposing a process-based approach for teaching UX in TPC classes and programs to provide scaffolding and connections for students.
Not Just Contrastive: Constructions with Negated Restrictives in English
Authors: Silvennoinen Olli O.
Published: November 2023

When restrictive adverbs are negated, an additive reading is produced (e.g., not only). This is particularly common in correlative constructions with a corrective part optionally introduced by but (e.g., not just in England but also in Scotland), but can also appear in other syntactic contexts. This study investigates formal and functional variation in the use of the four most common variants of negated restrictives ( not only, not just, not simply, and not merely) from the perspective of constructional and usage-based approaches to language. The study is based on a dataset of 1599 tokens, annotated for formal, functional, and extralinguistic variables, and is analyzed using hierarchical configural frequency analysis. The contrastive correlative construction not only X but ( also) Y appears as the central grammatical context for negated restrictives in English. In addition to its high frequency, not only displays the least variability in both form and function, which suggests a high degree of conventionalization. The less frequent variants of negated restrictives have more diffuse usage profiles, suggesting they are less conventionalized and may be emergent constructions which have not yet conventionalized into stable parts of the language. Methodologically, the study suggests an alternative to modeling alternations, which enables the detection of different degrees of conventionalization and which avoids conceptualizing alternations as choices conditioned by independent variables.
From Slums to Community: The Urban Turn of Catholicism in Post-War Brussels (1950-1975)
Authors: Minne Els
Published: November 2023

Adding to research on the link between religion and urbanization, this article explores how the notion of poverty influenced the relationship between Catholic actors and the city of Brussels (Belgium). It shows how the dynamics between clerics and urbanization changed on a local level because of the international renewal campaign of the Catholic Church in the 1960s. Before the Second Vatican Council, Catholics saw urban poverty as proof of the secularization process in modern European cities. From the 1960s onward, however, the Catholic clergy in Brussels—as well as in other European cities—started to refute the idea that religion and urbanization were irreconcilable, and instead urged for a positive attitude toward modern cities. By ceasing to associate modern cities with poverty, the Brussels vicariate stimulated its parish priests to engage in an active relationship with the city in order to shape its physical and social environment.
Earthmoving for the extraterrestrial
Authors: Nesbit Jeffrey S
Published: November 2023

The United States spaceport, and more importantly, its technical landscape, operate in the background for the technological and political progress in pursuit of the extraterrestrial. Throughout the construction of the launch complexes on the Florida coastline, earthmoving became standard practice to elevate rocket pads above sea level and protect against rocket blasts. However, a more extended history of earthmoving at Cape Canaveral is necessary. From Earth’s early geological formations and indigenous burial mounds to the modernization of rockets, Cape Canaveral presents itself as an evolution of terrestrial form. And still, earthmoving continues today. In 2016, an article advised the greatest threats to NASA's landscape are rising sea levels and hurricanes, causing substantial erosion to the beach, leaving active and historically significant launch facilities at risk. Cape Canaveral beaches are now preparing for additional dredging, importing new soil, and raising beach and dune elevations. This article reveals a critical history of place-based science on Cape Canaveral through an evolution of earthmoving practices, from cultural commemoration, extraterrestrial imagination, and contemporary environmental crises.
Examining the face threatening acts individuals with autism spectrum disorder experience and how they respond
Authors: Alvarez Cimmiaron F. , Wolfe Brooke H.
Published: November 2023

Individuals who have autism spectrum disorder (ASD) communicate differently than their neurotypical peers. Prior communication research on individuals with ASD has focused on how interventions can adapt the behaviors of those with ASD to be in line with neurotypical communication. This study treated the communication of individuals with ASD as a different, and valid, way of communicating, not something that needs intervening. We examined the face threats individuals with ASD experienced and the facework strategies they used in response. We found that individuals with ASD experienced (a) positive, (b) negative, and (c) hybrid face threats. In response to these face threats, individuals with ASD used (a) preventive, (b) corrective, and (c) future facework. Additionally, communication partners enacted facework on the behalf of individuals with ASD using (a) corrective and (b) future facework strategies. Face theory assumes that face threats (FTAs) and facework strategies are related; using thematic co-occurrence analysis, this study offered empirical evidence that FTAs and facework occur in patterned ways alongside a variety of practical applications.
Making the future a reality: Commitment assurances and time investment in daily life
Authors: Chandler Kylie R. , Don Brian P. , Jolink Tatum A. , Murphy Brett P. , Algoe Sara B.
Published: November 2023

Relatively little is known about how commitment manifests in couples’ everyday lives in a way that orients couples toward their future together. Building on the Investment Model of Commitment, we propose that, in everyday life, individuals with high levels of commitment are more likely to (a) assure their partners about the future of the relationship and (b) behaviorally invest in that future by spending more time in the partner’s presence. Results from a sample of individuals ( N = 100) suggest that relationship commitment is associated with greater time investment in the relationship (i.e., time spent with the partner in daily life); results from a second sample of couple members ( N = 269) replicate this effect and suggest that relationship commitment is associated with the use of daily assurances, which mediate the relationship between commitment and time spent co-present with the partner.
Mortality on extracorporeal membrane oxygenation: Evaluation of independent risk factors and causes of death during venoarterial and venovenous support
Authors: Deinzer Johannes , Philipp Alois , Kmiec Lukasz , Li Jing , Wiesner Sigrid , Blecha Sebastian , Petermichl Walter , Lubnow Matthias , Camboni Daniele , Schmid Christof , Stadlbauer Andrea
Published: November 2023

Introduction

Most patients on extracorporeal membrane oxygenation (ECMO) decease during therapy on the system. However, the actual causes of death have not been studied sufficiently. This study analyses the etiology, prevalence, and risk factors for the outcome variable death during ongoing ECMO for all patients and divided according to venoarterial (VA) or venovenous (VV) support.

Methods

We retrospectively analysed all patients receiving ECMO support at our institution between March 2006 to January 2021. Only the patients deceased during ongoing support were included.

Results

2016 patients were placed on VA ( n = 1168; 58%) or VV ( n = 848; 42%) ECMO; 759 patients (37.7%) deceased on support. The causes of death differed between the support types: VA ECMO patients mostly died from cerebral ischemia (34%), low-cardiac output (LCO; 24.1%) and multi-organ failure (MOF; 21.6%), whereas in VV ECMO cases, refractory respiratory failure (28.2%), and sepsis (20.4%) dominated. Multivariate regression analysis revealed cardiopulmonary resuscitation (CPR) and acidosis prior to ECMO as risk factors for dying on VA ECMO, while high inotropic doses pre-ECMO, a high fraction of inspired oxygen on day 1, elevated lactate dehydrogenase, and international normalized ratio levels lead to an unfavourable outcome in VV ECMO patients.

Conclusion

Even in highly experienced centers, ECMO mortality remains high and occurs mainly on support or 24 h after its termination. The causes of death differ between VV and VA ECMO, depending on the underlying diseases responsible for the need of extracorporeal support.