bluuebunny/crossref_metadata_2025 huggingface dataset:
MG53 E3 Ligase–Dead Mutant Protects Diabetic Hearts From Acute Ischemic/Reperfusion Injury and Ameliorates Diet-Induced Cardiometabolic Damage
Authors: Feng Han , Shen Hao , Robeson Matthew J. , Wu Yue-Han , Wu Hong-Kun , Chen Geng-Jia , Zhang Shuo , Xie Peng , Jin Li , He Yanyun , Wang Yingfan , Lv Fengxiang , Hu Xinli , Zhang Yan , Xiao Rui-Ping
Published: November 2021

Cardiometabolic diseases, including diabetes and its cardiovascular complications, are the global leading causes of death, highlighting a major unmet medical need. Over the past decade, mitsugumin 53 (MG53), also called TRIM72, has emerged as a powerful agent for myocardial membrane repair and cardioprotection, but its therapeutic value is complicated by its E3 ligase activity, which mediates metabolic disorders. Here, we show that an E3 ligase–dead mutant, MG53-C14A, retains its cardioprotective function without causing metabolic adverse effects. When administered in normal animals, both the recombinant human wild-type MG53 protein (rhMG53-WT) and its E3 ligase–dead mutant (rhMG53-C14A) protected the heart equally from myocardial infarction and ischemia/reperfusion (I/R) injury. However, in diabetic db/db mice, rhMG53-WT treatment markedly aggravated hyperglycemia, cardiac I/R injury, and mortality, whereas acute and chronic treatment with rhMG53-C14A still effectively ameliorated I/R-induced myocardial injury and mortality or diabetic cardiomyopathy, respectively, without metabolic adverse effects. Furthermore, knock-in of MG53-C14A protected the mice from high-fat diet–induced metabolic disorders and cardiac damage. Thus, the E3 ligase–dead mutant MG53-C14A not only protects the heart from acute myocardial injury but also counteracts metabolic stress, providing a potentially important therapy for the treatment of acute myocardial injury in metabolic disorders, including diabetes and obesity.
Closed-Loop Insulin Delivery Versus Sensor-Augmented Pump Therapy in Older Adults With Type 1 Diabetes (ORACL): A Randomized, Crossover Trial
Authors: McAuley Sybil A. , Trawley Steven , Vogrin Sara , Ward Glenn M. , Fourlanos Spiros , Grills Charlotte A. , Lee Melissa H. , Alipoor Andisheh Mohammad , O’Neal David N. , O’Regan Niamh A. , Sundararajan Vijaya , Colman Peter G. , MacIsaac Richard J.
Published: November 2021

OBJECTIVE

To assess the efficacy and safety of closed-loop insulin delivery compared with sensor-augmented pump therapy among older adults with type 1 diabetes.

RESEARCH DESIGN AND METHODS

This open-label, randomized (1:1), crossover trial compared 4 months of closed-loop versus sensor-augmented pump therapy. Eligible adults were aged ≥60 years, with type 1 diabetes (duration ≥10 years), using an insulin pump. The primary outcome was continuous glucose monitoring (CGM) time in range (TIR; 3.9–10.0 mmol/L).

RESULTS

There were 30 participants (mean age 67 [SD 5] years), with median type 1 diabetes duration of 38 years (interquartile range [IQR] 20–47), randomized (n = 15 to each sequence); all completed the trial. The mean TIR was 75.2% (SD 6.3) during the closed-loop stage and 69.0% (9.1) during the sensor-augmented pump stage (difference of 6.2 percentage points [95% CI 4.4 to 8.0]; P < 0.0001). All prespecified CGM metrics favored closed loop over the sensor-augmented pump; benefits were greatest overnight. Closed loop reduced CGM time <3.9 mmol/L during 24 h/day by 0.5 percentage points (95% CI 0.3 to 1.1; P = 0.0005) and overnight by 0.8 percentage points (0.4 to 1.1; P < 0.0001) compared with sensor-augmented pump. There was no significant difference in HbA1c between closed-loop versus sensor-augmented pump stages (7.3% [IQR, 7.1–7.5] (56 mmol/mol [54–59]) vs. 7.5% [7.1–7.9] (59 mmol/mol [54–62]), respectively; P = 0.13). Three severe hypoglycemia events occurred during the closed-loop stage and two occurred during the sensor-augmented pump stage; no hypoglycemic events required hospitalization. One episode of diabetic ketoacidosis occurred during the sensor-augmented pump stage; no serious adverse events occurred during the closed-loop stage.

CONCLUSIONS

Closed-loop therapy is an effective treatment option for older adults with long-duration type 1 diabetes, and no safety issues were identified. These older adults had higher TIR accompanied by less time below range during closed loop than during sensor-augmented pump therapy. Of particular clinical importance, closed loop reduced the time spent in hypoglycemic range overnight.
Increase in American Joint Committee on Cancer Stage at Diagnosis for Patients with Skin Cancers after the COVID-19 Lockdown
Authors: Nardin Charlée , Senot Lise , Pernot Paul , Puzenat Eve , Aubin François , Morin Lucas
Published: November 2021

Abstract is missing (Short communication)
Relationships Between Phubbing and The Five Factor Personality Traits
Authors: PARMAKSIZ İzzet
Published: November 2021

Purpose: Personality traits that distinguish the individual from others can be shown as one of the most important reasons of the individual's behavior. In this study, it was aimed to determine the predictive effect of personality traits on phubbing by considering the relationship between phubbing and personality traits (extraversion, conscientiousness, agreeableness, neuroticism, and openness). Design/Methodology/Approach: The study group of the research consisted of 1186 [Female: 642 (54.1%), Male: 544 (45.9%)] individuals living in different provinces of Turkey. Simple random sampling method was used in the study. The ages of the participants were range from 15-70 (Mean ± sd = 31.24 ± 11.38). The research data were collected using Phubbing Scale, Adjective Based Personality Test and Personal Information Form. Descriptive statistics, t-test, One-Way Anova, Pearson correlation, and hierarchical regression were used in the analysis of the research data. Findings: According to the findings obtained from the study, there was no significant relationship between phubbing and extraversion. While there was a significant positive relationship between phubbing with neuroticism and openness. There were negative relationships between phubbing with conscientiousness and agreeableness. According to the preliminary analysis, while gender did not differentiate phubbing scores significantly; marital status, educational level and age significantly differentiated phubbing scores. According to the results of the hierarchical regression analysis, it has been found that conscientiousness, agreeableness, neuroticism, and openness were predictors of phubbing. Highlights: Personality traits are an important factor that needs to be addressed in order to understand phubbing behavior. The research findings were discussed in terms of literature and suggestions are made.
O sentido do brincar e do jogar na infância humana como fundamentos para a construção da democracia social
Authors: Da Silveira Carmem Lúcia Albrecht , Lauer Munir José , Esquinsani Rosimar Serena Siqueira
Published: November 2021

O artigo tem por objetivo discutir o sentido do brincar e do jogar, no período de desenvolvimento da infância do ser humano, como elementos fundamentais da educação cidadã democrática. A investigação realiza umarevisão qualitativa da contribuição bibliográfica e teórica de Mead (2010), Casagrande (2014), Kishimoto (2011) e Maturana (1994) sobre o tema. Inicialmente, aborda o processo de desenvolvimento da autoconsciência na criança, considerando o brincar e o jogar como condições sociais interativas necessárias para tal fim. Em seguida, aborda a questão da democracia como obra de arte, produzida diariamente pelo conviver fraterno, e enfatiza o brincar e o jogar como seus fundamentos, pois tais atividades auxiliam na construção do eu democrático. A convivência democrática é fundamentalmente educativa, ao ensinar as crianças pela compreensão, pelo diálogo, pela tomada de consciência, pela correção do erro como elemento construtivo e inerente à aprendizagem.
A constituição da identidade docente e suas implicações nas práticas educativas de professores de uma universidade comunitária
Authors: Aparecida Colognese Rech Rose , Boff Eva Teresinha de Oliveira
Published: November 2021

A identidade é um processo que emerge da percepção que temos sobre nós mesmos como sujeitos históricos, construída de acordo com o contexto, as vivências e as relações que cada pessoa estabelece comos outros e com o mundo. Este texto objetiva identificar e analisar os fatores que influenciaram na constituição da identidade docente e as suas implicações nas práticas educativas de um grupo de professores do ensino superior de uma universidade comunitária. A pesquisa seguiu uma abordagem qualitativa, de caráter descritivo, por meio de uma entrevista semiestruturada. Os professores foram questionados de forma que pudessem rememorar sua trajetória de vida pessoal e profissional. Para esta investigação, encontramos aportes teóricos nos estudos acerca da temática “identidade profissional” na obra de Dubar (2005) e sobre a formação do professor do ensino superior em Pimenta e Anastasiou (2014), entre outros autores. A análise dos dados foi fundamentada na Análise Textual Discursiva de Moraes e Galiazzi (2016), que propõe três momentos: desmontagem dos textos, estabelecimento das relações e captação do novo emergente. De acordo com as afirmações dos professores, analisadas à luz do referencial teórico, consideramos que o professor tem seu ingresso na docência do ensino superior pelo perfil investigativo, tornando sua iniciação repleta de insegurança pela falta de conhecimentos específicos da docência. Esse profissional vai constituindo-se e identificando-se com a profissão no decorrer da trajetória docente pelos saberes práticos, resultantes das interações humanas estabelecidas no cotidiano acadêmico. Tais saberes necessitam ser refletidos criticamente segundo os referenciais do campo da educação. Por isso, são necessários, no âmbito da instituição, processos de profissionalização continuados que possibilitem que os saberes da prática sejam problematizados e reconstruídos pelos professores, tanto individual como coletivamente.
Agroecologia e Pedagogia da Alternância: um estudo de caso da Escola Tecnológica de Fraiburgo, Santa Catarina
Authors: Domingues Sérgio , Ferreira dos Santos Júnior Cezário , Nunes Aline , Bonadiman Ariel
Published: November 2021

O objetivo da pesquisa foi compreender como o ensino de Agroecologia em uma escola agrícola, em regime de Pedagogia da Alternância, tem influenciado no ensino-aprendizagem dos estudantes e como isso tem afetado o âmbito familiar e comunitário. Utilizaram-se as metodologias quantitativa, com aplicação de questionário aos estudantes, e qualitativa, baseada em entrevistas abertas e estruturadas aos estudantes, professores, pais e pessoas ligadas à fundação da escola. O processo de ensino-aprendizagem baseado na interação com a realidade local, como propõe o método “Tempo Escola e Tempo Comunidade” aplicado na Pedagogia da Alternância, mostrou-se efetivo por apresentar maior ligação com as relações do campo. Os entrevistados relatam que essa metodologia tem proporcionado maiores trocas de conhecimento com a família e a comunidade, o que pode influenciar positivamente as formas de cultivo a partir de um novo pensar. No entanto, verificou-se que há uma distorção relacionada às práticas agrícolas locais e ao ensino de Agroecologia. De acordo com os estudantes e pais, há necessidade de realizar a transição agroecológica, pois muitos ainda seguem práticas convencionais de cultivo,  o que dificulta o uso dos conhecimentos adquiridos pelos estudantes. Compreende-se que a alteração de paradigmas é feita gradativamente e a Pedagogia da Alternância aplicada ao ensino de Agroecologia pode auxiliar no aprimoramento de práticas para que as mudanças ocorram.
As vivências como metodologia de ensino da extensão rural: a aproximação entre estudantes e agricultores para a compreensão da realidade social
Authors: Dos Santos Facco Hector , Diska Nathana Marina , Pinto da Silva Gustavo
Published: November 2021

A qualificação dos espaços de ensino por meio de metodologias que coloquem os estudantes em interação com a realidade é vista como uma forma de promover a formação dos profissionais das Ciências Agrárias com uma visão mais holística. Nesse sentido, o presente relato de experiência tem como objetivo contextualizar e problematizar uma experiência metodológica a partir da mediação e condução do elemento curricular de Extensão Rural no curso Técnico em Agropecuária, por meio de vivências de práticas sociais como forma de reflexão sobre a complexidade dos sistemas agrícolas. Deve-se considerar que o elemento curricular de Extensão Rural é tido como o espaço adequado para tratar dos processos de intervenção e mediação dos futuros profissionais. A atividade que será descrita foi desenvolvida no curso Técnico em Agropecuária, modalidade subsequente, do Colégio Politécnico da Universidade Federal de Santa Maria (UFSM), ao longo do segundo semestre de 2019. O conteúdo foi desenvolvido com alternância de aulas teóricas e vivências em propriedades da agricultura familiar do município de Agudo, Rio Grande do Sul, e organizado em conjunto com a prefeitura e a Emater-RS/Ascar. Como resultado, podem ser destacados o maior comprometimento dos estudantes, o diálogo com a sociedade e um processo mais crítico e reflexivo de ensino. A construção dessa proposta foi inspirada na vivência profissional da extensão rural e baseada nas perspectivas em diálogo com contribuições das correntes pedagógicas, como a histórico-crítica e a construtivista.
O lugar da educação não escolar nos currículos de Pedagogia
Authors: Serejo de Souza Mariana Aparecida
Published: November 2021

Este artigo apresenta resultados de estudo que teve por objetivo analisar como a dimensão da educação não escolar, especificamente, é abordada nos projetos curriculares do curso de Pedagogia, tendo em vista asdiversas exigências formativas estabelecidas pelas Diretrizes Curriculares Nacionais, aprovadas em 2006. A proposta metodológica foi estruturada em dois momentos: 1) revisão bibliográfica, na qual buscamos aportes que inter-relacionam a educação não escolar com a Pedagogia e referenciais da teoria curricular para lançar luzes sobre a compreensão do texto das diretrizes curriculares; e 2) pesquisa documental, na qual examinamos dez projetos pedagógicos do curso de Pedagogia de instituições de educação superior do Distrito Federal, destrinchando-os em categorias temáticas, por meio das quais efetuamos a análise do conteúdo levantado. Após a imersão nos dados, chegamos ao entendimento de que essas instituições formam o pedagogo docente em atenção às diretrizes do curso, mas sinalizam para os espaços de atuação profissional além da escola, especialmente ao delinearem disciplinas e estágios supervisionados que contemplem esse campo. Porém, observamos o isolamento e a desconexão desses componentes curriculares em relação à proposta formativa geral, o que indica a necessidade de engendrar propostas curriculares mais efetivas para abarcar a dimensão não escolar na formação dos pedagogos.
Autoconfrontação cruzada em grupo focal: recurso metodológico para pesquisas em Educação
Authors: Zanetti Giordan Miriane , Medeiros Sarti Flavia
Published: November 2021

Este artigo apresenta e discute a autoconfrontação cruzada em grupo focal como recurso metodológico para pesquisas em Educação. O procedimento foi elaborado e explorado no âmbito de uma pesquisa sobre a circulação de saberes entre docentes em espaços formativos sistematizados. A proposta metodológica resultante encontra respaldo, de um lado, em pressupostos ligados à clínica da atividade, especialmente nos trabalhos de Yves Clot – que propõe os procedimentos de autoconfrontação simples e cruzada – e, de outro, na tradição dos grupos focais, cujo emprego em pesquisas educacionais vem se disseminando e ampliando nas últimas décadas. Trata-se de procedimento afinado aos pressupostos da pesquisa qualitativa, voltada à produção de conhecimentos que nos auxiliem na interpretação da realidade vivida pelos sujeitos. Considera-se que a autoconfrontação cruzada em grupo focal constitui alternativa interessante para a investigação de temas complexos – como costuma ser o caso na Educação –, oferecendo, ainda, possibilidades para intervenções de ordem formativa em grupos sociais.
Social Alienation in “The Foreigner” A Novel by Arun Joshi
Authors: Rani Khusboo
Published: November 2021

The alienation of men and women in society is conditionally contextualized according to past birth karma as a belief. Currently, men and women want to avoid being tortured, marginalized by society from a social point of view. Sometimes the situation is very critical and there are people who have suddenly lost everything. The belief is that costiveness will turn into an innovation. The crisis is that those who turned the progress of living it into an opportunity. Arun Joshi tried in his fiction novel “the Foreigner” with a character Sindi Oberoi who believed in the cyclical misfortune of losing his childhood family. The shelter collapsed from his head, and he was standing there thinking of a meaningless life and struggling to commit suicide. Everyone is alienated here from birth to death. Only our karma must live a segregated life that shines like gold.
ANALISIS KEPUASAN NASABAH BANK BRI KANTOR CABANG SIDOARJO
Authors: Yunita Sari Renny , Budiarto Bambang , Hariadi Sugeng
Published: November 2021

This study discusses the influence of service quality and product quality on customer satisfaction at the Bank BRI branch office in Sidoarjo. The data used in this study were obtained from the results of a questionnaire that had been distributed to customers of the BRI branch office in Sidoarjo. This quantitative research was conducted with a survey method with purposive samplin technique. The variables used in this study are independent variables that include service quality and product quality, and customer satisfaction as the dependent variable. The data analysis method used in this study is multiple linear regression analysis. The results showed that the quality of service and product quality can affected customer loyalty at the bank branch office in Sidoarjo.
Big Five Personality Traits and Motivation in Learning Mandarin as Foreign Language
Authors: Jung Ku Chen , Yoke Lian Lau , Rizal Hamid , Rau Krishnan Anath , Amin Hanudin , Samsulbahri Mohd Nasir , Ghazali Mohd Fahmi
Published: November 2021

Abstract: The present study aims to develop a model illuminating the relationship between student personality traits and motivation towards learning Mandarin as a foreign language. A model framework consisting of five exogenous variables and one endogenous variable of motivation are examined in the present study. Sample of 260 undergraduates taking Mandarin language at public university in East Malaysia was used as respondents for the present work. The path analysis revealed that the big five personality traits significantly influence and explained 52% of the variance in students' motivation. The analysis further indicates that extraversion and conscientiousness produce the strongest correlation with students' motivation. The results inferred that students who enjoy social visibility and self-discipline are also who will be motivated to learn the Mandarin language. Findings also demonstrated that agreeableness positively influence motivation, and neuroticism, as expected, produce negative direct relations with motivation towards learning Mandarin as a foreign language. On the contrary, the present study did not find any correlation between openness and motivation. The implications of this study are also discussed and interpreted within the context of what educators could do to encourage students' motivation.

 

Keywords: Big five, Extraversion, Mandarin language, Neuroticism, Personality traits.
Pharmacy Students’ Perceptions and Performance from a Microlearning-based Virtual Practical on the Elucidation of Absolute Configuration of Drugs
Authors: Yan Choo Chee , Abdul Rahim Aisyah Saad
Published: November 2021

Abstract: The Covid-19 Movement Control Order imposed by the government converted the delivery of lessons to online learning in the education sector. Pharmaceutical chemistry is a core subject for pharmacy students and first-year students were taught the elucidation of the absolute configuration of active pharmaceutical ingredients (API).  The objective of this study is to investigate the pharmacy students’ perceptions and performance on learning new knowledge related to the concept of absolute configuration on API through micro-learning.  Students were introduced and assessed on the stereochemistry of new terminologies through micro-learning activities.  Various 3D molecular model capture in video format was uploaded on YouTube(YT) and embedded in the Google Form(GF) online assessment.  The students’ video navigation was captured with YT video analytics, students learning performance was through GF quiz assessment responses, and the student’s attitudes through questionnaire survey.  In conclusion, the performance of student pharmacists in learning and applying new knowledge delivered through online distance micro-learning was comparable to face-to-face active learning.  Both YT video analytics and GF responses allowed real-time monitoring and interventions.  Nonetheless, students required more time to learn new knowledge online compared to face-to-face active learning. In conclusion, the designed virtual micro-learning enabled students to learn bite-sized new knowledge while training their spatial ability through the application of 3D molecular models with reinforcement through quizzes. The virtual micro-learning design is practical and economical without much technological investment or training for both the educator and learner with easy access in an open distance learning environment and post-Covid.

 

Keywords: Absolute configuration, Analytics, Micro-learning, Online assessment, Video
Technology Addiction among UiTM Puncak Alam and UNNES Semarang Students
Authors: Johan Zaimy Johana , Hafit Nor Intan Adha , Tusyanah Tusyanah
Published: November 2021

Abstract: Technology addiction has become an alarming disorder that has increasingly caught the attention of researchers, mental health counsellors and doctors. Unfortunately, those who are having the disorder do not realize that they are going through the phase of pleasurable, addictive experience of appealing themselves by long hours of social networking, gaming, and internet browsing; and affecting their psychological well-being. The symptoms of depression, anxiety, loneliness, avoidance of work and procrastination may be overlooked and hence be left untreated. The purpose of this study is to identify the factors contributing to technology addiction among UiTM Puncak Alam and UNNES, Semarang students applying SPSS v. 23. Data were collected from 656 undergraduate students of the two universities who participated in the survey: 317 and 339 questionnaires were collected from UiTM Puncak Alam, Selangor, Malaysia and UNNES, Semarang, Indonesia students respectively. The results show technology usage influenced technology addiction but psychological well-being did not affect technology addiction. Additionally, UiTM Puncak Alam students are more technology addicted compared to UNNES Semarang students. This distressing condition could become worse during the current Covid-19 pandemic period and prolonged movement control order (MCO) for students, regardless whether they stay at home or on campus. Implications of the findings are further discussed.

 

Keywords: Covid-19,Psychological Well-being,Technology Addiction, Technology Usage, University Students
Acceptance, Readiness and Intention to Use Augmented Reality (AR) in Teaching English Reading among Secondary School Teachers in Malaysia
Authors: Mohamed Jamrus Mohd Hafizuddin , Razali Abu Bakar
Published: November 2021

Abstract: This research reports on Malaysian English teachers’ readiness and acceptance in using Augmented Reality (AR) in English instruction and their intention to use AR in teaching English reading. Through a survey on 181 Malaysian English language teachers in Klang Valley, Malaysia, it was found that Malaysian English teachers possess quite a high level of acceptance in using Augmented Reality in the teaching of English reading with 60.8 % (n = 110); and have a high level of readiness in using Augmented Reality in the teaching of English reading at 63.0% (n = 114). The researchers also found significant correlation between level of acceptance and behavioral intention (r = .935**, p = .00, p < .05) between teachers’ acceptance with their intention to use Augmented Reality in teaching of English reading at .05 level of significance. There is also high correlation between teachers’ readiness with intention to use augmented reality in teaching English reading, with the correlation coefficient (r), at .924.  In conclusion, Malaysian secondary school teachers’ acceptance and readiness to use Augmented Reality (AR) in teaching English reading are high and there is a positively significant relationship between acceptance and readiness with intention to use AR in teaching English reading.

 

Keywords: Acceptance, Augmented Reality, English Language Learning, English Reading, Readiness, Intention to Use
Ability of RTK-Based GPS Measurement Method in High Accuracy Work in Geomatics Study
Authors: Nordin Nor Azme , Mustapa Noraishah , Abdul Satar Asiah
Published: November 2021

Abstract: Insfrastructure development require significant changes and transformation in Geomatics field for the upcoming decade. The use of new technology in Geomatics and surveying is essential and can be leveraged in many survey application that will help on building the nation towards a sustainable future. In the last 5 years, GNSS technology has been widely used and practiced to replace total station for survey work. Main factors that contributes to this busniness changes are the availability of much cheaper equipment with good technical capability in the market that helps surveyor to perform their work faster and more efficient. Global navigation satellite system services for accurate positioning has also rapidly increased and provide many option and solution for industry player or surveyor to choose. Combination of multiple global navigation satellite system providers such as GPS, GALILEO,GLONASS and BeiDOU has developed good satellite networks and increased numbers of available satellites for observation that improve absolute position accuracy. CHC i70 is among the best selling GNSS model on the market right now. The receiver can receive signal from GPS,GALILEO,GLONASS and BeiDOU simultaneously. This study will outline and focus on the capability of the RTK-Based method ( 30 second to 1 minute observation period) using CHC i70 instrument in high-precision measurement work. The research was done using the GPS calibration test site at Politeknik Sultan Haji Ahmad Shah (POLISAS) and was also practiced in the actual work for establishment of Temporary Bench Mark (TBM) along Jalan Melor to Ketereh, Kelantan. The result of the study found that RTK-Based method can meet the precision work that is permitted under 2cm accuracy. Studies show that the method of using RTK- Based is suitable for high precision work and improve the measurement time and work duration at field.

 

Keywords : Beidou, Chc and RTK-Based GPS and PDOP
Socioeconomic correlates of catfish production status in Ido Local Government Area of Oyo State, Nigeria
Authors: Oke Folasade Olukemi , Kiyesi Cynthia , Akerele Dare
Published: November 2021

Knowledge of the socioeconomic characteristics of fish farmers is crucial for increased output in fish production so as to bridge the gap between the current level of production and ever-increasing demand for fish due to its contribution to human population growth and development. The study examined the relationship between farmers’ socioeconomic characteristics and output in catfish production in Oyo State, Nigeria. A multistage sampling technique was used in the selection of 120 catfish farmers. Primary data were collected through structured questionnaire from the selected catfish farmers. The data obtained from the farmers were analysed using descriptive statistics and ordinary least square (OLS) regression. Findings revealed that majority (63.3 %) of the farmers were male, 65 % were within the active and productive age of 31 – 40 years, capable of withstanding the stress in catfish production. Majority (82.4 %) of the farmers were married with an average household size of five individuals. The fish farmers were highly educated with most (91.8 %) of them having tertiary education. Two-thirds of the farmers were members of a cooperative society out of which 52.5 % were loan beneficiaries. Most (62.5 %) of the farmers operated on a part-time basis and managed between 1 – 2 ponds with output worth below N 500,000 ($1,315.79) per production cycle. The OLS regression result revealed that fish output was significantly determined by age (p < 0.01), marital status (p < 0.05) of fish farmers, education (p < 0.05), and cooperative membership (p < 0.05). Although there were indications of economic prosperity in catfish production in the study area, efforts to promote access to education and participation in cooperative society are critical to output expansion. This will engender knowledge acquisition and sharing, promote capacity building and synergies that will advance production outputs and business performance.
Controlling and the Use of UAVs as Important Components of Smart Logistical Operations
Authors: Holubčík Martin , Soviar Jakub
Published: November 2021

Modern controlling is an interdisciplinary field that allows management to manage properly, thereby creating the basis for good decision-making. Logistics operations in smart companies need to be not only properly set up, but also properly controlled and improved. The purpose of the article is to analyze the controlling environment in a selected company and point out possible improvements in logistics activities and devices, with a view to preventing different types of problems. For this purpose, observations of the internal logistics processes in a selected company were used and quantified to assess its internal state. On the basis of the data, controlling measures are put forward to improve the management of the company’s logistics activities. The results of the research highlight the opportunities that exist through controlling activities to collect and analyze information about the logistics activities of a company. By doing so, employees can be given greater responsibility for the fulfilment of their tasks and contribute to the streamlining of logistics processes. For managers, the implementation of controlling represents a change in the way of thinking and managing a company.
Experience of using Rituximab in neurological practice (literature review and own observation)
Authors: Kushnir Ya. B. , Tereshchenko N. M. , Abramova M. P. , Gotovchikov A. A. , Polushin A. Yu. , Krasnov V. S.
Published: November 2021

Currently, due to the lack of specific etiotropic therapy, rituximab is widely used for the treatment of most autoimmune diseases of the central and peripheral nervous system. Rituximab is a chimeric monoclonal antibody with specificity for CD20, the antigen found on the surface of normal and malignant B-lymphocytes. It is used mainly in hematological practice. It is used off-label for the treatment of neurological diseases. The world literature describes the use of rituximab for the treatment of such pathologies as autoimmune encephalitis, neuromyelitis optica spectrum disorder, multiple sclerosis, primary angiitis of the central nervous system, immune-mediated inflammatory polyneuropathy, myasthenia gravis, refractory to basic immunosuppressive therapy. This article provides an overview of the world literature on the use of rituximab in neurological practice, describes our own experience of its use on the basis of the Department of Neurology № 1 of Pavlov University (Saint Petersburg, Russia).
Parameters of the corpus callosum and thalamuses in mesocephalic women of the second period of mature age according to MRI data
Authors: Balandin A. A. , Balandina I. A. , Zheleznov L. M.
Published: November 2021

Introduction. One of the most important parts of the brain from a morphofunctional point of view is the corpus callosum and the thalamus. Today, the problem of the lack of clear morphometric characteristics of these parts of the brain in mesocephalic women of the second period of mature age is obvious.

The objective of the study was to establish the morphometric characteristics of the corpus callosum and thalamuses in mesocephalic women of the second period of mature age using the method of magnetic resonance imaging.

Methods and materials. The results of morphometric examination of the corpus callosum and thalamuses of 37 women aged 36 to 54 years using magnetic resonance imaging were analyzed. We determined the length and height of the corpus callosum, knee thickness, cushion thickness, its depth (anterior, upper and posterior). The transverse, longitudinal, and vertical dimensions of the thalamuses were determined.

Results. The morphometric characteristics of the corpus callosum is characterized by the predominance of the knee thickness over the thickness of the cushion (p<0.01). The parameter of the posterior depth of the corpus callosum prevails over the parameters of the upper and anterior depths of its occurrence (p<0.01). When comparing the parameters of the upper depth and the anterior depth of the corpus callosum, there is a tendency for the upper depth indicator to prevail (p>0.05). The regularity of the morphometric characteristics of the thalamuses is the tendency to the predominance of all parameters in the left hemisphere (p>0.05).

Conclusions. The results of the comparative analysis of the morphological characteristics of the corpus callosum in the elderly and senile age supplement the knowledge of age-related anatomy and will be useful in the clinical practice of doctors of radiation diagnostics and magnetic resonance imaging offices.
On the issue of critical arterial stenosis
Authors: Suprunovich A. A. , Bedrov A. Ya. , Vrabiy A. A. , Moiseev A. A. , Baykova A. V. , Kalmykova R. V. , Dolzhikova A. S.
Published: November 2021

Cardiovascular disease (CVD) is the leading cause of death worldwide. The main contribution to the structure of mortality from CVD is made by atherosclerosis. Indications for surgical treatment of patients with diseases caused by atherosclerotic lesions of the arteries are set taking into account the degree of their stenosis. Angiography has been considered the gold standard for screening patients with CVD for many years. Numerous studies carried out over the past several decades have revealed the weak side of this method in assessing the significance of borderline stenosis. Therefore, to analyze such changes, functional tests were introduced to clarify the indications for surgical intervention. Currently, criteria for the significance of stenosis of the iliac, renal and coronary arteries have been determined. The significance of stenosis of the arteries supplying the brain and intestines is still a matter of debate and requires further study.
Personal Branding Psikolog Seto Mulyadi (Kak Seto) di Era Disrupsi Media
Authors: Juliastuti Rina , Witarti Denik Iswardani
Published: November 2021

The rapid technological development has made social media much sought-after in the public. Social media has been widely used in building personal branding. But this is not the case with child psychologist Kak Seto who has no personal account in any of social media platforms, while his activities in the world of children always become an attraction and have news value. The formulation of the problem in this research is how the personal branding of Kak Seto in the era of media disruption. The purpose of this research is to explain the activities of Kak Seto in the context of "a friend of children", reveal what media he uses, and analyze his personal branding in the era of media disruption. This study uses a constructivist paradigm, through qualitative approaches and descriptive research methods. A series of activities he carries out is seen from the conventional types of media he uses. From the results of the analysis in this study, it was proven that conventional media have a strong ability to build the personal branding of Kak Seto. The power of his personal branding which correlates with a good image to meet his expectation as a friend of children has been embedded in the minds of the community.
Bertahan untuk Hidup: Konvergensi Pers Cetak dalam Industri Digital Media
Authors: Hutomo Mulyono Sri
Published: November 2021

Mass media industry particularly print media in Indonesia comes under heavy pressure to survive in the era of digital disruption. High printing costs, coupled with high distribution costs and employee salaries have caused difficulties for print media companies to maintain their businesses. Some print media companies have opted to shut down their businesses, while others have survived by making various efficient efforts and diversifying their businesses.   The convergence of print media into digital media has offered an alternative to maintain print media as the management of Telaah Strategis magazine has done.   This research aims to see the efforts made by the management of Telaah Strategis magazine to survive in the media industry in Indonesia. The results of this research show that Telaah Strategis magazine uses a variety of media convergence models to be able to maintain its task of disseminating information by transforming it into a news portal and digital magazine and appearing in the social media platform. In addition, it also markets its digital magazine at online product sale exchange.
Makna Simbolik Elemen-Elemen Lantai Teras Arupadhatu Candi Borobudur
Authors: Darmayuda I Gusti Putu
Published: November 2021

Penelitian ini menganalisis makna simbolik elemen-elemen lantai teras Arupadhatu candi Borobudur menggunakan Semiotika Charles Sanders Peirce, dan Susanne Langger. Metode pendekatannya adalah kualitatif. Hasil penelitian adalah makna simbolis lantai teras Arupadhatu serta elemen-elemennya berdasarkan ajaran filosofis Buddha. Makna simbolik lantai teras Arupadhatu adalah unsur yang tak berwujud, merupakan simbol dari tahapan perjalanan spritual sang Buddha menuju kesempurnaan. Jalan menuju kesempurnaan disimbolkan dengan lantai teras melingkar bersusun tiga. Lantai teras lingkar terbawah adalah teras 7, lantai di atasnya teras 8. Di lantai teras 7 dan 8 terdapat stupa terawang belah ketupat, merupakan simbol dari jiwa yang masih terikat unsur-unsur pikiran dualisme. Di lantai teras 9 terdapat elemen stupa terawang bujur sangkar, merupakan simbol dari pencapaian keseimbangan jiwa, sehingga roh suci mampu masuk ke tahapan berikutnya menuju pencerahan tertinggi: sang roh suci berada di Alam kesunyata atau nirwana, terbebas dari ikatan reinkarnasi sesuai dengan tujuan utama ajaran Buddha. Perjalan akhir menuju ke-Buddhaan disimbolkan dengan elemen teras lantai 10, ditandai dengan elemen stupa Agung di puncak bangunan:  simbol dari alam semesta.
Konstruksi Pemberitaan Kompas.com dan Republika.co.id tentang Kebijakan Pasangan Turis Bukan Muhrim Menginap Sekamar di Arab Saudi
Authors: Suryana Ahmad
Published: November 2021

Arab Saudi merupakan negara ultrakonservatif yang menerapkan hukum Islam dalam perundang-undangannya di berbagai sektor termasuk sektor pariwisata. Arab Saudi mulai melirik sektor pariwisata dalam upaya keluar dari ketergantungan terhadap minyak bumi. Sebelum tahun 2018, banyak peraturan ketat yang mengekang perempuan di Arab Saudi, diantaranya larangan menyetir dan bepergian tanpa mahram. Sejumlah aturan ketat tersebut kini mengalami pelonggaran, salah satunya dihapusnya larangan pasangan bukan suami isteri menginap dalam satu kamar bagi turis asing yang datang ke Arab Saudi. Studi ini menganalisis pemberitaan kompas.com dan republika.co.id terkait kebijakan pemerintah Arab Saudi memperbolehkan pasangan turis asing bukan suami isteri menginap dalam satu kamar. Analisis yang digunakan adalah framing Zhongdang Pan dan dan Gerald M. Kosicki.
Play Victim dalam Lirik Lagu-Lagu Taylor Swift
Authors: Muharman Deddy , Kartika Nindita , Mercia Mega
Published: November 2021

Taylor Swift, dituding melakukan playing victim dan berperan sebagai korban dari mantan kekasihnya. Hal ini terlihat dari lirik lagu yang dibuatnya setelah ia patah hati dan seakan ditujukan untuk mantan kekasihnya. Lagu tersebut antara lain Shake It Off, You Belong with Me, Blank Space, Love Story, dan I Knew You Were Trouble. Tujuan penelitian ini untuk mengetahui bagaimana Taylor Swift melakukan Play Victim melalui lagunya; mengetahui apakah penggemar Taylor Swift menyadari sang idola melakukan Play Victim dan apakah mereka tetap menjadi penggemar Taylor Swift setelah tahu apa yang dilakukan olehnya? Penelitian ini menggunakan metode kualitatif. Data primer diperoleh melalui wawancara mendalam dengan fans Taylor Swift dan data sekunder dari artikel majalah, website dan berita. Hasil penelitian menunjukkan, secara implisit Taylor Swift melakukan playing victim dan menjadi korban dari mantan kekasihnya. Dia juga merasa dirinya adalah korban dari ejekan dan cacian para haters-nya. Meski begitu, Taylor tidak peduli dengan apa yang dikatakan oleh orang lain. Menurutnya, tidak ada yang bisa mengatur opini atau perkataan orang lain.
Gaya Komunikasi Guru dan Motivasi Belajar Siswa pada Pembelajaran Daring di Masa Pandemi COVID-19
Authors: Fadhilah Alifia Nurul , Iqbal Fajar
Published: November 2021

Penelitian ini mengkaji besaran pengaruh gaya komunikasi guru terhadap motivasi belajar siswa pada pembelajaran daring masa pandemi COVID-19. Pandemi COVID-19 sejak tahun 2020 berdampak pada Pendidikan di Indonesia khususnya dalam kegiatan belajar mengajar yang dilakukan secara online. Di masa pandemi COVID-19 merupakan sebuah tantangan bagi para guru untuk menumbuhkan motivasi belajar siswa yang rendah pada pembelajaran daring. Guru sebagai tenaga pendidik dan pengajar menjadi seseorang yang memegang peranan penting dalam mewujudkan generasi penerus bangsa yang cerdas dan berprestasi. Gaya komunikasi guru diduga kuat sangat mempengaruhi motivasi belajar siswa. Pada penelitian ini motivasi belajar siswa diukur menggunakan referensi teori kemungkinan elaborasi yang dikembangkan Richard Petty dan John Cacioppo. Penelitian ini merupakan penelitian kuantitatif dengan teknik pengumpulan data menggunakan kuisioner. Analisis data menggunakan rumus analisis regresi linier sederhana yang digunakan untuk mengetahui besar pengaruh gaya komunikasi guru terhadap motivasi belajar siswa, menggunakan IBM Statictic versi 25. Penelitian ini dilakukan terhadap 70 siswa kelas delapan di MTs Negeri 4 Bantul yang dilakukan secara online. Hasil penelitian ini menunjukkan, terdapat pengaruh yang signifikan antara gaya komunikasi guru terhadap motivasi belajar siswa pada pembelajaran daring masa pandemi COVID-19. Pertambahan motivasi belajar siswa sangat ditentukan oleh gaya komunikasi guru saat melaksanakan kegiatan belajar mengajar secara daring pada masa pandemi COVID-19.
Komunikasi Word of Mouth sebagai Penentu Keputusan Membeli Produk
Authors: Wibowo Arief , Satiri Satiri , Ruliana Poppy , Yulianto Kresno
Published: November 2021

Tujuan penelitian ini adalah untuk mengetahui pengaruh komunikasi Word of Mouth (WOM) terhadap keputusan pembelian barang di Nano Komputer, sebuah toko yang mempunyai fokus dalam menjual barang elektronik berupa komputer serta kebutuhan kantor lainnya. Nano Komputer melakukan metode penyampaian pesan kepada konsumen dengan cara promosi dari mulut ke mulut. Metode yang digunakan adalah survei yang diberikan kepada kelompok yang akan diteliti. Rancangan penelitian ini memiliki tujuan untuk mencari pengaruh antar dua variable yaitu Variabel (X), Word of Mouth sedangkan variabel (Y) adalah Keputusan Pembelian. Responden yang dilibatkan dalam penelitian ini adalah karyawan Kompleks Perkantoran Kartini Depok yaitu 96 orang. Metode pengambilan sampel menggunakan purposive sampling. Pengumpulan data menggunakan kuesioner akan diberikan kepada responden. Hasil dari penelitian menunjukkan terdapat pengaruh yang positif antara variabel Word of Mouth (WOM) terhadap Keputusan Pembelian yang didukung oleh hasil survei dan perhitungan secara statistik menggunakan software SPSS, dengan kata lain seluruh karyawan Kompleks Perkantoran Kartini Depok yang membeli kebutuhan computer di NanoKomputer dipengaruhi oleh komunikasi Word of Mouth.
Analysis of the Use of Close Friend Feature on Instagram as a Social Networking Site Using Communication Privacy Management Theory
Authors: Sakinah Sofa
Published: November 2021

The development of digital media technology gave rise to social media, especially Instagram which is a site used to exchange information and fulfill social communication needs in various circles. This study specifically analyzes the use of the Close Friend feature found on Instagram social media which is used for various objectives of each user. The research method uses descriptive quantitative content analysis through text analysis from various previous studies related to the use of the Instagram feature. One study showed that the effectiveness of the Instagram feature in increasing adolescent friendships in the digital era was dominant in the Close Friends feature as much as 61.2%. Close friends feature (close friend) was promoted because of the self-disclosure factor, as well as the convenience of users in uploading Instagram stories. The level of openness to the high categorydue to the proximity selecting and content sharing on this feature. The close friends feature is considered more private for Instagram users because they are free to choose their audience and upload based on their needs and desires. It was also mentioned how users manage their privacy when using the Instastory feature on Instagram social media where the privacy management is based on the Communication Privacy Management (CPM) criteria or Communication Privacy Management and is seen in the usage strategy when using the Insta Story feature on Instagram. Informants tend to have different reasons behind their decision to reset their privacy when using their social media.
Retorika Deliberative: Komunikasi Marah Marah Pejabat di Ruang Publik
Authors: Amrihani Haresti Asysy
Published: November 2021

Seorang pemimpin memiliki peran strategis dalam memimpin organisasi untuk mencapai tujuan organisasi. Pemimpin diharapkan memiliki gaya komunikasi yang bisa diterima oleh semua anggota elemen organisasi. Padahal, gaya retorika komunikasi seorang pemimpin dipengaruhi oleh berbagai situasi dinamis yang dihadapinya dalam memimpin organisasi, sehingga adakalanya dia tampil dengan gaya komunikasi yang temperamental atau marah-marah. Penelitian ini bertujuan menggali lebih dalam gaya retorika pemimpin organisasi yang juga pejabat publik dan bersikap tempramental dalam berkomunikasi kepada khalayaknya. Studi ini menggunakan pendekatan kualitatif dengan menerapkan teori retorika Aristoteles dan social judgement theory sebagai pisau analisisnya. Temuan studi ini adalah, pejabat publik menggunakan gaya retorika deliberative dalam berkomunikasi dengan khalayaknya di ruang publik. Sebagian audience bisa menerima gaya retorika pejabat publik tersebut (latitude of acceptance), namun ada yang menolak (latitude of rejection), dan ada yang menyatakan tidak menghiraukannya (latitude of noncommitment).