bluuebunny/crossref_metadata_2025 huggingface dataset:
Scanning electron microscopy and X-ray spectroscopy applied to mycelial phase of sporothrix schenckii
Authors: Thibaut M. , Ansel M.
Published: June 2013

Scanning electron microscopy applied to the mycelial phase of Sporothrix schenckii shows a matted mycelium with conidia of a regular pattern. X-Ray microanalysis applied in energy dispersive spectroscopy and also in wavelength dispersive spectroscopy reveals the presence of several elements of Mendeleef's classification.
Testes de susceptibilidade de agentes da cromomicose à 5-fluorocitosina e ao butil-simpatol (Vasculat)
Authors: Resende Maria Aparecida de , Oliveira Luiz Gonzaga de , Lopes Cid Ferreira , Cisalpino Eduardo Osório
Published: June 2013

Foram realizados testes de susceptibilidade "in vitro" com várias amostras de agentes, isoladas de pacientes com cromomicose frente à 5-fluorocitosina e ao butil-simpatol (Vasculat), nas concentrações de 0,1, 1,0, 5,0 10,0 mcg/ml. Em alguns casos, em que se verificou resistência à 5-fluorocitosina, a concentração desta chegou a 100,0 mcg/ml.
Abnormal eating behaviors among medical students at a university in southern Santa Catarina, Brazil
Authors: Alberton Vivian Comelli , Dal-Bó Márcio José , Piovezan Anna Paula , Silva Rosemeri Maurici da
Published: June 2013

OBJECTIVES: Disturbances in eating behavior significantly affect young adults. This study aimed to estimate the prevalence of abnormal eating behaviors, according to the Eating Attitudes Test - 26 (EAT-26) in medical students at a university in southern Santa Catarina State, Brazil. METHODS: Self-reported questionnaire, based on the EAT-26 scale, was administered to medical students. Additional questions about age, gender, study period of the course, weight and height were asked. A total of 391 medical students were assessed, amounting to 93.3 percent of the 419 students enrolled. RESULTS: Ten percent of the surveyed subjects had positive EAT-26 scores. This outcome measure was positive associated with females (PR 6.5), body mass index (BMI) ≤ 25 kg/m² (PR 4.5), age ≤ 20 years (PR 1.3) and being student from 1st to 5th semester of the course (PR 1.7). A higher proportion of women gave positive responses to behaviors related to control of food intake or weight loss than men. CONCLUSION: The significant prevalence of behaviors related to eating disorders, predominantly among women, suggests the implementation of preventive measures targeting this population.
Escritas da brasilidade: subjetivação e política lusófona na documentação vernacular
Authors: Magalhães Anderson Salvaterra
Published: June 2013

Neste trabalho, o objetivo é demonstrar como escritas sobre o Brasil fundamentam e são fundamentadas por valores determinantes dos discursos que constroem o senso de vernáculo. São analisados a "Carta" de Pero Vaz de Caminha, escrita chave para a produção do discurso da brasilidade, e o poema "Erro de português", de Oswald de Andrade, tomado como reformulação da escrita fundadora. A implicação ética do acabamento estético das duas escritas em língua portuguesa articula processos de subjetivação que definem identidades culturais possíveis e atualiza uma política linguística que confere tensão entre o caráter genitivo e locativo do vernáculo, respectivamente, do Brasil e no Brasil.
Vigor of canola seeds through quantification of CO2 emission
Authors: Dranski João Alexandre Lopes , Pinto Júnior Artur Soares , Herzog Neusa Francisca Michelon , Malavasi Ubirajara Contro , Malavasi Marlene de Matos , Guimarães Vandeir Francisco
Published: June 2013

Seed marks the beginning of grain production from cultivated crops. Ensuring seed quality is the priority in the field of seed technology. In this context, the purpose of this study was to evaluate the use of carbon dioxide concentration to Classify Brassica napus seed lots of different quality resulting from various sowing dates. Seed lots were evaluated by percentage of normal plantlets and the germination rate index. CO2 concentration was quantified in samples submitted to five periods of incubation at 40° C with the aid of a gas exchange analyzer coupled to an injection and airflow system. The results were subjected to analysis of variance and the mean values were compared by the Duncan test and by regression analysis at the 5% level of significance. B. napus seeds from all lots showed a high percentage of normal plantlets and germination rate index. Percentage of normal plantlets was correlated with CO2 concentration. Determination of the CO2 concentration was more efficient with three hours of incubation which allowed classification of canola seed lots into four vigor classes. CO2 concentration was inversely proportional to the percentage of normal plantlets.
Hállux Rígidus: estudo prospectivo da substituição articular com hemiartroplastia
Authors: Santos Alexandre Leme Godoy dos , Duarte Fernando Aires , Seito Carlos Augusto Itiu , Ortiz Rafael Trevisan , Sakaki Marcos Hideyo , Fernandes Túlio Diniz
Published: June 2013

OBJETIVO: Relatar os resultados com médio prazo de seguimento após a implantação de Arthrosurface-HemiCap® em pacientes com diagnóstico de hállux rígidus (HR). MÉTODO: Onze pacientes foram submetidos à artroplastia parcial da primeira metatarso-falangeana. Seis mulheres e cinco homens com idade média de 51,9 anos (46 a 58 anos) e média de seguimento pós-operatório de 3,73 anos (3-4 anos); foram classificados através do sistema de Kravitz e avaliados pelas escalas da american orthopaedic foot and ankle society (AOFAS) para hállux, visual analog scale (VAS) - analógico funcional de dor - e pela amplitude de movimento da primeira articulação metatarsofalangeana no periodo pré-operatório, pós-operatório de seis meses e pós-operatório atual. RESULTADOS: Os resultados revelam melhora significativa dos três parâmetros analisados no estudo, tanto para análise global como para comparações pré e pós-operatórias individuais. A análise comparativa de cada variável nos períodos pós-operatórios de seis meses e atual não mostram diferença estatística o que indica manutenção dos parâmetros durante esse intervalo. CONCLUSÃO: A hemiartroplastia da primeira metatarsofalangeana é opção reprodutível e segura para o tratamento cirúrgico do hállux rígidus II e III, com significativa melhora dos parâmetros avaliados para a população estudada. Nível de Evidência IV, Série de casos.
Avaliação de bolsas de produtividade em pesquisa do CNPq e medidas bibliométricas: correlações para todas as grandes áreas
Authors: Wainer Jacques , Vieira Paula
Published: June 2013

Este trabalho estuda as correlações entre decisões tomadas no fim de 2009, sobre renovação ou não de bolsas de produtividade em pesquisa do CNPq e medidas bibliométricas. Para cada nível da bolsa e para cada subárea, calculamos a correlação da decisão em subir o pesquisador de nível, mantê-lo no nível original ou rebaixá-lo, com várias medidas bibliométricas, como produção total (artigos, conferências, livros e capítulos de livros), produção nos últimos 5 anos, produção indexada no Web of Science, citações recebidas por artigo, citações recebidas por artigo escrito nos últimos 5 anos, índice H, etc. Os dados de citações foram extraídos tanto do Google Scholar como do Web of Science. As correlações de cada subárea são agrupadas em cada uma das 8 grandes áreas do CNPq (Ciências Agrícolas, Ciências Biológicas, Ciências Exatas, Ciências Humanas, Ciências da Saúde, Ciências Sociais, Engenharia e Artes). Indicamos quais são as métricas bibliométricas com maior correlação, com as decisões do CNPq para cada nível e para cada uma das grandes áreas. Discutimos algumas grandes áreas nas quais parece haver uma maior coerência, através dos vários níveis da bolsa entre as métricas mais correlacionadas com as decisões.
Flavonol glycosides found in hydroethanolic extracts from Tilia cordata, a species utilized as anxiolytics
Authors: Negri G. , Santi D. , Tabach R.
Published: June 2013

Tilia species, among which is Tilia cordata Mill. (Tiliaceae), have been used in folk medicine as anxiolytic. The hydroethanolic extract was analyzed by using liquid chromatography with mass spectrometry HPLC-DAD-ESI-MS/MS in negative ion mode, and its chemical composition was compared to flavonoids reported as anxiolytics. The major flavonoids found were: quercetin-3,7-di-O-rhamnoside, kaempferol-3,7-di-O-rhamnoside and kaempferol 3-O-(6"-p-coumaroyl glucoside) or tiliroside. The anxiolytic activity of the genus Tilia has been attributed to the presence of quercetin and kaempferol derivatives, while the anxiolytic activity of T. americana var. Mexicana was attributed to tiliroside, which was also found among the major constituents of this species.
Atividade anti-helmíntica de plantas nativas do continente americano: uma revisão
Authors: Sousa R.G. , Falcão H.S. , Barbosa Filho J.M. , Melo Diniz M.F.F. , Batista L.M.
Published: June 2013

O presente trabalho faz uma revisão de plantas nativas do continente americano com atividade anti-helmíntica com a finalidade de subsidiar pesquisas e o desenvolvimento de novos medicamentos na área de produtos naturais. Na literatura, foram citadas 22 famílias de plantas, tais como: Moraceae, Asteraceae e Cucurbitaceae, e estudadas cerca de 35 espécies, como a Ficus sp, Cucurbita máxima, e Ruta graveolens, usadas por sua alegada atividade anti-helmíntica. Destas espécies, 26 foram ativas contra alguns helmintos: Strongyloides stercolaris, Ancylostomidae, Trichostrongylus sp, Capillaria sp, Ascaris lumbricoides, Taenia saginata, Haemonchus contortus, e Hymenolepsis diminuta. Foi verificado maior número de estudos com parasitas de animais, possivelmente devido ao desenvolvimento de resistência dos helmintos aos tratamentos convencionais disponíveis.
Caracterização das estratégias de reparo incomuns utilizadas por um grupo de crianças com desvio fonológico
Authors: Backes Fabieli Thaís , Pegoraro Silvana Pereira , Costa Vanessa Pires , Mota Helena Bolli
Published: June 2013

OBJETIVO: caracterizar e analisar o uso das estratégias de reparo incomuns por crianças com desvio fonológico e relacionar a sua utilização com as variáveis faixa etária e sexo; e com as variáveis linguísticas grau do desvio, estrutura silábica, classe de sons e posição na palavra. MÉTODOS: os dados são provenientes do banco de dados do Centro de Estudos de Linguagem e Fala da Universidade Federal de Santa Maria, todos os sujeitos apresentam Termo de Consentimento Livre e Esclarecido autorizando o uso dos dados em pesquisas. Foram selecionados os dados de 178 sujeitos que apresentaram diagnóstico de desvio fonológico e idade entre 4:0-7:11. Foram analisados os resultados da primeira avaliação fonológica da criança. RESULTADOS: houve significância estatística na relação entre a utilização ou não de estratégias de reparo incomuns na amostra estudada, predominando a não utilização. Foi significante a relação entre a utilização de tais estratégias e a faixa etária, com predomínio na faixa de 5:0-5:11, e o grau do desvio, com maior ocorrência no desvio moderadamente-grave. A relação entre as classes de sons também foi significante, predominando a classe das fricativas. Observou-se ocorrência de estratégias de reparo incomuns apenas na posição de onset, sendo a estrutura consoante vogal a única encontrada no estudo. CONCLUSÃO: verificou-se que as estratégias de reparo incomuns são pouco utilizadas por crianças com desvio fonológico. Além disso, encontrou-se relação significante entre a utilização de estratégias de reparo incomuns e as variáveis faixa etária, grau do desvio fonológico e classes de sons.
Efeito residual do extrato de Annona coriacea sobre Aedes aegypti
Authors: Dill E.M. , Pereira M.J.B. , Costa M.S.
Published: June 2013

A produção de extratos vegetais da família Annonaceae é uma alternativa eficaz no controle do vetor da dengue, e sua aplicabilidade está relacionada à persistência do produto no ambiente. O objetivo desta pesquisa foi avaliar o efeito residual do extrato de Annona coriacea (Mart., 1841) sobre a mortalidade de Aedes aegypti (Linnaeus, 1762). Foram utilizados recipientes plásticos de 25 L, para distribuir as concentrações de 50 e 100 ppm do extrato, e DMSO (1%) e água foram usados como controle. Estes recipientes ficaram expostos na área externa do laboratório. Nos dias 1, 8, 15, 30 e 45 dias após o preparo, coletou-se uma amostra de 1,3 L de cada tratamento. Foram utilizadas oito réplicas com 25 larvas de A. aegypti para os dois tratamentos, e quatro réplicas para os controles. O registro da mortalidade das larvas foi feito diariamente e foi observada a mortalidade de pupas e adultos. O experimento foi conduzido aleatoriamente, no esquema fatorial 4 x 5. Os dados foram submetidos à análise de variância pelo teste F e as médias dos tratamentos foram comparadas pelo teste de Tukey (p < 0,05). A concentração de 100 ppm do extrato de A. coriacea apresentou efeito residual de 100% de mortalidade de larvas durante o período de 15 dias, e não houve eficiência na mortalidade de pupas e adultos. Portanto, o efeito residual apresentado por A. coriacea sobre larvas de A. aegypti indica que o extrato desta planta pode ser utilizado em programas de controle da dengue.
Isolamento de Salmonella Heidelberg em diferentes pontos da tecnologia de abate de frangos de corte
Authors: Colla F.L. , Rodrigues L.B. , Borsoi A. , Dickel E.L. , Nascimento V.P. do , Santos L.R. dos
Published: June 2013

Bactérias do gênero Salmonella fazem parte da flora normal das aves e sua ocorrência em produtos avícolas varia com o manejo na criação e tecnologia de abate, representando riscos para o consumidor final e dificuldades nas exportações. A S. Heidelberg parece ser mais invasiva e causar doenças com maior gravidade que outros sorovares paratíficos. Este trabalho teve por objetivos pesquisar Salmonella em diferentes pontos da tecnologia de abate de frangos e relatar o isolamento de S. Heidelberg em um abatedouro sob inspeção federal. S. Heidelberg foi isolada em frangos logo após a depenagem e na água do chiller indicando que, embora não tenha sido realizado o isolamento em outros pontos amostrados, a bactéria estava presente no ambiente e poderia contaminar carcaças prontas para consumo, com reflexos na saúde pública. O isolamento de S. Heidelberg reforça esta preocupação uma vez que este sorovar tem se destacado como causador de doenças transmitidas por alimentos.
Eficácia do diflubenzuron 25% no controle da Haematobia irritans (Diptera: Muscidae): desafio in vitro e a campo
Authors: Dell' Porto A. , Hoppe E.G.L. , Gomes A.G. , Mata R.S.S. , Rocha R.M. de S.
Published: June 2013

Avaliou-se, neste experimento, a eficácia in vitro e in vivo do diflubenzuron a 25% para uso em bovinos, no controle da infestação por Haematobia irritans. Para o teste in vitro, ovos de moscas-dos-chifres foram mantidos em recipientes contendo fezes de animais não-tratados ou tratados com diflubenzuron a 25%, e acompanhados até emergência dos adultos. No teste in vivo, foram utilizadas 40 fêmeas aneloradas, divididas em dois grupos: controle (C) e tratado (T) com intensidade parasitária equivalente. Durante o experimento, o grupo C recebeu apenas suplementação mineral, enquanto o grupo T recebeu suplementação mineral e diflubenzuron a 25%. A contagem de moscas nos animais foi realizada na região dorsal, desde a nuca até as pontas da anca de cada animal, no início e ao final de um período de cinco meses. Na avaliação in vitro, o grupo controle apresentou média de emergência de 86% (± 8,4%), enquanto o grupo cultivado em fezes de bovinos tratados com diflubenzuron a 25% apresentou taxa de emergência média de 1% (± 0,2%), sendo a eficácia calculada de 98,83%. No teste in vivo, não foi observada redução significativa na contagem de moscas no grupo C, porém, no grupo T houve significativa redução da infestação por H. irritans (t = 16,46, p < 0,0001). A eficácia do produto, em condições de campo, foi de 99,20%. O diflubenzuron a 25% adicionado ao sal mineral mostrou-se eficaz contra H. irritans, sendo indicado para esse fim.
Análise das importações brasileiras como fatores de risco de difusão da encefalopatia espongiforme bovina no país
Authors: Rodrigues D.L. , Barros Filho I.R. de , Warth J.F.G. , Ollhoff R.D.
Published: June 2013

Nesta pesquisa são apresentadas e analisadas as importações brasileiras de bovinos e seus produtos derivados que representam risco para a Encefalopatia Espongiforme Bovina (EEB) reali-zadas no período de 2002 a 2009, conforme protocolo da Organização Mundial da Saúde Animal (OIE), no intuito de identificar riscos potenciais nas mercadorias internalizadas. Para tanto, foram utilizados os dados de tipo, volume e origem das importações, taxas de incidência e classificação de risco da EEB dos países exportadores disponibilizados pelo Ministério do Desenvolvimento, Indústria e Comércio Exterior, Ministério da Agricultura, Pecuária e Abastecimento e pela OIE. Neste período foram importados 476 bovinos vivos de países que registraram a EEB (Canadá e EUA), 7.791.295 kg de produtos destinados à alimentação animal dos EUA e 36.038 kg originários da Malásia. Também foram identificadas importações de produtos de origem bovina destinados ao consumo humano no período: 156.869 kg dos EUA, 1600 kg da Itália e 1 kg da Espanha e para fins farmacêuticos: 37.194 kg de pâncreas bovino dos EUA e mais 457.719 kg de glândulas de origem animal (sem definição de espécie) também provenientes dos EUA, as quais, segundo a OIE, devem ser consideradas na análise de risco de introdução do agente, apesar de suas respectivas finalidades. Foi possível concluir que as mercadorias importadas, apesar do potencial identificado, representaram baixo risco de introdução do agente no território nacional e que os volumes diminuíram gradativamente no período analisado.
Eficácia do glyphosate e 2,4-D no controle de Commelina villosa
Authors: Campos C.F. de , Rodrigues-Costa A.C.P. , Cardoso L.A. , Pereira M.R.R. , Souza G.S.F. de , Martins D.
Published: June 2013

O objetivo do presente trabalho foi avaliar a eficácia de glyphosate e 2,4-D, isolados e em mistura, no controle de Commelina villosa. Foram estudadas duas metodologias de avaliação de absorção de herbicidas em oito intervalos de tempo para a lavagem (simulando chuva após a aplicação) e corte (simulando abortamento, como estratégia de defesa) das folhas: 2, 4, 6, 8, 12, 24 e 48 horas após a aplicação dos herbicidas, além de um tratamento sem lavagem ou corte das folhas, em delineamento experimental inteiramente casualizado com quatro repetições, dispostos em um esquema fatorial 3 x 7 + 1 (três herbicidas x sete períodos - horas após a aplicação). Os herbicidas e doses testados foram: glyphosate (1.440 g ha-1), 2,4-D (720 g ha-1) e a mistura glyphosate + 2,4-D (1.080 + 720 g ha-1). A simulação de chuva interferiu de forma negativa no controle das plantas com o herbicida glyphosate. O controle com o herbicida 2,4-D foi influenciado apenas no período de 2 horas. Os períodos de simulação de chuva não influenciaram no controle das plantas com a mistura de glyphosate + 2,4-D. Para o estudo com corte das folhas tratadas, todos os tratamentos independente do período para corte das folhas foram influenciados de forma negativa no controle, sendo que as plantas apresentaram rebrotas quando tratadas com o herbicida 2,4-D isolado.
Resposta humoral de bovinos vacinados contra as toxinas botulínicas tipos C e D em diferentes faixas etárias
Authors: Curci V.C.M. , Zocoller-Seno M.C. , Nogueira A.H.C. , Araujo R.F. de , Cardoso T.C. , Dutra I.S.
Published: June 2013

Foi verificada pelo teste de ELISA indireto a resposta humoral contra os toxoides botulínicos C e D em bovinos de diferentes idades. O estudo envolveu 90 animais, que foram divididos em três grupos (n = 30), de acordo com a sua faixa etária; inferior a 2 anos de idade (G1), entre 2 e 5 anos (G2) e superior a 5 anos (G3). Os grupos experimentais foram vacinados com duas doses de vacina antibotulínica bivalente (C e D) comercial, nos dias 0 e 42 após a primo-vacinação (booster). Na avaliação, quando realizada 30 dias após o booster, os animais do G3 apresentaram maior produção de anticorpos (p < 0,05) em relação aos demais grupos. Entre o G1 e G2 não houve diferença significativa na resposta humoral contra a toxina C, no entanto, contra a toxina D, os animais do G1 apresentaram maior produção de anticorpos. Todos os grupos produziram uma resposta significativa de anticorpos contra as toxinas botulínicas após a 2ª dose da vacina bivalente comercial, principalmente contra o tipo D.
Sinais comportamentais dos Transtornos do Déficit de Atenção com Hiperatividade e do Processamento Auditivo: a impressão de profissionais brasileiros
Authors: Pereira Valéria Reis do Canto , Santos Teresa Maria Momensohn , Feitosa Maria Angela Guimarães
Published: June 2013

OBJETIVO: Caracterizar os sinais comportamentais do Transtorno do Déficit de Atenção com Hiperatividade (TDAH) e do Transtorno do Processamento Auditivo (TPA), segundo a visão de profissionais que atuam no diagnóstico e intervenção relacionados a estes transtornos no Brasil. MÉTODOS: Participaram 42 profissionais (médicos, fonoaudiólogos, psicólogos e pedagogos). Todos responderam a um questionário contendo 58 sinais comportamentais de TDAH e TPA. Cada participante foi orientado a classificar os comportamentos de acordo com a frequência de ocorrência, elencando-os em categorias de 1 (nunca) a 5 (sempre). Os valores da média geral deste estudo foram comparados aos valores da média apresentados em estudo norte americano similar. RESULTADOS: Verificou-se que alguns sinais comportamentais foram mais citados do que outros em ambos os transtornos. No TDAH os sinais comportamentais mais evidentes foram: dificuldade em brincar silenciosamente, distraído, desorganizado, desatento, hiperativo, irrequieto, muda de um trabalho incompleto para o outro, pouco autocontrole, falta de persistência e apressado ou impulsivo. No TPA os sinais comportamentais mais evidentes foram: déficit na atenção auditiva dividida, déficit na atenção auditiva seletiva, dificuldade em seguir instruções orais, habilidade de associação auditiva ruim, dificuldade de ouvir em ambiente ruidoso, déficit na atenção auditiva sustentada, dificuldade em discriminar fala e taxa reduzida de processamento da informação auditiva. CONCLUSÃO: Foi possível concluir que os profissionais classificaram determinados sinais comportamentais como mais evidentes no TDAH e outros mais evidentes no TPA.
Resolução temporal em perdas auditivas sensorioneurais
Authors: Matos Giselle Goulart de Oliveira , Frota Silvana
Published: June 2013

OBJETIVO: Avaliar a resolução temporal em adultos com perdas auditivas sensorioneurais de graus leve e moderado, por meio do teste Gaps in Noise (GIN), a fim de verificar se essas perdas influenciam no desempenho do teste. MÉTODOS: Foram avaliados 57 pacientes, com idades entre 20 e 59 anos (30 homens e 27 mulheres), que realizaram anamnese, avaliação otorrinolaringológica, avaliação audiológica básica e triagem do processamento auditivo, com o teste Dicótico de Dígitos. Os sujeitos foram alocados nos grupos G1 (audição normal), G2 (perda auditiva leve) e G3 (perda moderada). Foi realizada análise estatística apropriada e o nível de significância adotado foi de 5%. RESULTADOS: Observou-se presença significativa de homens no grupo com perda auditiva. Não foram encontradas diferenças significativas no desempenho do referido teste entre os grupos. Porém, no grupo controle, foram observados piores desempenhos, quando comparados com o critério de normalidade previsto para adultos jovens brasileiros. A média do limiar de detecção de gaps, da amostra geral, foi de 8,2 ms, em ambas as orelhas, e a média das porcentagens de acertos foi de 49,7% para a orelha direita (OD) e de 50,6% para a orelha esquerda (OE). CONCLUSÃO: A habilidade de resolução temporal avaliada pelo teste GIN não sofre influência da perda auditiva sensorioneural de graus leve e moderado, tanto nos limiares de detecção de gaps quanto na porcentagem de acertos, em ambas as orelhas.
Field Treatment To Stimulate a Deep, Sour, Tight-Gas Well Using a New, Low-Corrosion and Environmentally Friendly Fluid
Authors: Nasr-El-Din H.A.. A. , de Wolf C.A.. A. , Stanitzek T.. , Alex A.. , Gerdes S.. , Lummer N.R.. R.
Published: June 2013

Matrix acidizing of high-temperature gas wells is a difficult task, especially if these wells are sour or if they are completed with high-chrome-content tubulars. These harsh conditions require high loadings of corrosion inhibitors and intensifiers in addition to hydrogen sulfide scavengers and iron control agents. Selection of these chemicals to meet the strict environmental regulations adds to the difficulty in dealing with such wells. Recently, a new environmentally friendly chelating agent, glutamic acid-diacetic acid (GLDA), has been developed and extensively tested for carbonate and sandstone formations. Significant permeability improvements have been shown in previous papers over a wide range of conditions. In this paper, we evaluate the results of the first field application of this chelating agent to acidize a sour, high-temperature, tight gas well completed with high-chrome-content tubulars.

Extensive laboratory studies were conducted before the treatment, including corrosion tests, coreflood experiments, compatibility tests with reservoir fluids, and reaction-rate measurements using a rotating disk apparatus. The treatment started by pumping a preflush of mutual solvent and water-wetting surfactant, followed by the main stage consisting of 20 wt% GLDA with a low concentration of a proper corrosion inhibitor. Following the treatment, the well was put on production, and samples of flowback fluids were collected. The concentrations of various ions were determined using ICP. Various analytical techniques were used to determine the concentration of GLDA and other organic compounds in the flowback samples.

The treatment was applied in the field without encountering any operational problems. A significant increase in gas production that exceeded operator expectations was achieved. Unlike previous treatments where hydrochloric acid (HCl) or other chelates were used, the concentrations of iron, chrome, nickel, and molybdenum in the flowback samples were negligible, confirming low corrosion of well tubulars. Improved productivity and longer-term performance results confirm the effectiveness of the new chelate as a versatile stimulation fluid.
Primary Cardiac Fibroma and Cardiac Conduction System Alterations in a Case of Sudden Death of a 4-month-old Infant
Authors: Mecchia Donatella , Lavezzi Anna Maria , Matturri Luigi
Published: June 2013

A 4-month-old female infant considered to be in good health died suddenly and unexpectedly. Post- mortem examination was requested, with clinical diagnosis of sudden infant death syndrome. At autopsy the infant was described in good health. Histo- logical examination of the heart found a cardiac fibroma compressing the atrio-ventricular node and the examination of the cardiac conduction system showed an accessory fiber of Mahaim (nodo-ventricular) and cartilaginous metaplasia of the cardiac fibrous body. Probably the concomitant presence of cardiac conduction system abnormalities and a septal fibroma, compressing the atrio-ventricular node, could have an important role in causing the sudden death.
Early Progression of Diabetic Nephropathy Correlates With Methylglyoxal-Derived Advanced Glycation End Products
Authors: Beisswenger Paul J. , Howell Scott K. , Russell Gregory B. , Miller Michael E. , Rich Stephen S. , Mauer Michael
Published: June 2013

OBJECTIVE

Increased advanced glycation end products (AGEs) and oxidation products (OPs) are proposed to lead to progression of diabetic nephropathy (DN). We investigated the relationship between AGEs, OPs, and progression of DN in 103 subjects with type 1 diabetes participating in the Natural History of Diabetic Nephropathy Study.

RESEARCH DESIGN AND METHODS

Mean age of subjects was 17.6 ± 7.4 years, and mean duration of diabetes was 8.3 ± 4.9 years. All patients were normoalbuminuric. Change in glomerular basement membrane (GBM) width from baseline to 5 years, measured using electron micrographs of renal biopsies, was our primary end point, and mesangial fractional volume was a secondary end point. Fast progressors (FPs) were defined as those in the upper quartile of GBM change, and the remaining patients were classified as slow progressors (SPs). AGEs (3-deoxyglucosone and methylglyoxal hydroimidazolones [MGHI]), carboxymethyl lysine (CML), carboxyethyl lysine (CEL), and OPs (methionine sulfoxide and 2-aminoadipic acid) were measured at year 5 by liquid chromatography/triple-quadruple mass spectroscopy on 10-K plasma filtrates.

RESULTS

We found that MGHI, CEL, and CML levels were significantly higher in FPs relative to SPs. No product predicted mesangial expansion. A model containing only HbA1c accounted for 4.7% of GBM width variation, with the total variability explained by the model increasing to 11.6% when MGHI, CEL, and CML were added to the regression model (7.9% increase). MGHI was a significant independent predictor of FP. Using a logistic regression model to relate each biomarker to the probability of a subject’s classification as an FP, CML, CEL, and MGHI, but not HbA1c, showed a significant relationship to the probability of FP.

CONCLUSIONS

The results suggest that these three major AGEs may be early indicators of progression of important DN lesions.
Association Between Remission of Macroalbuminuria and Preservation of Renal Function in Patients With Type 2 Diabetes With Overt Proteinuria
Authors: Yokoyama Hiroki , Araki Shin-ichi , Honjo Jun , Okizaki Shinichiro , Yamada Daishiro , Shudo Ryushi , Shimizu Hitoshi , Sone Hirohito , Moriya Tatsumi , Haneda Masakazu
Published: June 2013

OBJECTIVE

Studies on the rate of remission of macroalbuminuria in patients with type 2 diabetes mellitus (T2DM) and the effects of reduction in albuminuria on renal prognosis in a primary care setting are absolutely lacking.

RESEARCH DESIGN AND METHODS

A total of 211 T2DM patients with albuminuria ≥300 mg/g were enrolled in a prospective observational study (mean of 4.5 years). The incidence of patients with remission of macroalbuminuria at every 1-year study time point after starting intensified diabetes treatment and the factors associated with remission were evaluated. The association of reduction in albuminuria with renal events (doubling of serum creatinine and end-stage renal disease) was also investigated.

RESULTS

During the 5-year study period, remission to microalbuminuria occurred in 116 patients and the 5-year cumulative incidence was 58.3%. Notably, most cases (82.8%) obtained remission at the 1-year study time point. The remission rate increased with achieving therapeutic targets for blood pressure and blood glucose. Remission and reduction in albuminuria of ≥50% were associated with preservation of renal function. In particular, patients who obtained both remission and 50% reduction at the 1-year study time point exhibited a significantly reduced risk for renal events as compared with those with no remission and no reduction (adjusted hazard ratio 0.30 [95% CI 0.12–0.76]).

CONCLUSIONS

Remission of macroalbuminuria occurs frequently and is associated with the preservation of renal function in T2DM patients. The initial adequate diabetes treatment aimed at reducing albuminuria may lead to improved renal prognosis in the primary care setting.
Acceleration and flotation of a glacier terminus during formation of a proglacial lake in Rhonegletscher, Switzerland
Authors: Tsutaki Shun , Sugiyama Shin , Nishimura Daisuke , Funk Martin
Published: June 2013

In 2005 the ongoing retreat of Rhonegletscher, Switzerland, led to the formation of a proglacial lake. To investigate the influence of proglacial lake formation on the dynamics and evolution of glaciers, we measured horizontal flow velocity, vertical ice motion and water levels in boreholes with high spatial resolutions during the summer seasons of 2007–09. Annual flow speeds near the terminus increased by a factor of 2.7 from 2005/06 to 2007/08, and exceeded 20 m a−1 in 2009. The velocity increased towards the glacier front, indicating that the ice was thinning under a longitudinally stretching flow regime. Our observations show that the increase in flow speed near the terminus was due to increases in basal motion as a result of ice thinning. During summer 2009, the ice surface at the terminus moved vertically upwards by up to 4.69 m as the ice began to float on the lake. The observed ice motion can be explained by the upward bending of marginal ice and the formation of faults that cut through the entire ice thickness. We predict that if the current ice thinning continues, the basal water pressure will exceed the pressure exerted by the ice overburden, and the glacier will progressively disintegrate over an expanding area.
From Climate Advocacy to Public Engagement: An Exploration of the Roles of Environmental Non-Governmental Organisations
Authors: Szarka Joseph
Published: June 2013

The capacity of non-governmental organisations (NGOs) to encourage public engagement with climate protection is analysed through a conceptual framework focused on six advocacy functions: issue framing, knowledge generation and dissemination, attribution of responsibility, lobbying, public mobilisation and agenda setting. This framework is used to organise and interpret the results of a fieldwork study of environmental NGOs, conducted in France, Germany and the UK. Key findings include the importance of the cross-linkage of climate with other categories of issue, NGO stress on knowledge as a precursor to action, a ‘politics of accountability’ in which the attribution of responsibility paves the way for making political demands, a preference for multi-layered lobbying, where process can be as important as product, and the need to adjust NGO mobilisation and agenda setting strategies in the aftermath of the 2009 Copenhagen negotiations and the financial crisis.
Unraveling Results from Comparable Demand and Supply: An Experimental Investigation
Authors: Niederle Muriel , Roth Alvin , Ünver M.
Published: June 2013

Markets sometimes unravel, with offers becoming inefficiently early. Often this is attributed to competition arising from an imbalance of demand and supply, typically excess demand for workers. However this presents a puzzle, since unraveling can only occur when firms are willing to make early offers and workers are willing to accept them. We present a model and experiment in which workers’ quality becomes known only in the late part of the market. However, in equilibrium, matching can occur (inefficiently) early only when there is comparable demand and supply: a surplus of applicants, but a shortage of high quality applicants.
Putative Genes Involved in Saikosaponin Biosynthesis in Bupleurum Species
Authors: Lin Tsai-Yun , Chiou Chung-Yi , Chiou Shu-Jiau
Published: June 2013

Alternative medicinal agents, such as the herb Bupleurum, are increasingly used in modern medicine to supplement synthetic drugs. First, we present a review of the currently known effects of triterpene saponins-saikosaponins of Bupleurum species. The putative biosynthetic pathway of saikosaponins in Bupleurum species is summarized, followed by discussions on identification and characterization of genes involved in the biosynthesis of saikosaponins. The purpose is to provide a brief review of gene extraction, functional characterization of isolated genes and assessment of expression patterns of genes encoding enzymes in the process of saikosaponin production in Bupleurum species, mainly B. kaoi. We focus on the effects of MeJA on saikosaponin production, transcription patterns of genes involved in biosynthesis and on functional depiction.
How Does HIV Affect the Reproductive Choices of Women of Childbearing Age?
Authors: Haberl Annette , Reitter Anke
Published: June 2013

The majority of women living with HIV are of childbearing age and many of these women wish to have a family. As a result of advances in the treatment and management of HIV, more reproductive opportunities are now available to this group. However, women living with HIV may still require education and guidance in a range of reproductive situations, including avoiding pregnancy, seeking fertility treatment or having a child. HIV physicians should be aware of recent data and guidance on these situations – including areas where more data are required – and consider them when deciding on appropriate management for their patients.
What Do We Know about Antiretroviral Treatment of HIV in Women?
Authors: Monforte Antonella d'Arminio , Anderson Jane , Olczak Anita
Published: June 2013

As the number of women living with HIV continues to increase, the lack of sex-specific data on responses to antiretroviral therapy (ART) becomes increasingly problematic. Establishing the specific needs of women has been hampered by a strong male bias of study populations in clinical trials resulting in a lack of female-specific data for ART. The limited data currently available make it difficult to draw conclusions about the pharmacokinetic profile and clinical efficacy of ART in women. Data relating to the safety and tolerability profiles of ART in women are more plentiful, with indications that women may experience adverse event profiles distinct from those experienced by men. This, in turn, may be a factor in the generally higher rates of discontinuation of ART observed in women. Psychological and social aspects of HIV infection are particularly pertinent for women and girls, presenting potential barriers to diagnosis, access and adherence to therapy. Understanding these factors, in conjunction with an increase in clinical trial and real-world data specific to women with HIV is required to provide clearer guidance on optimum ART options for women.
Preliminary Results of a Prospective Study on Severe Lower Limb Trauma: Analysis of Laboratory Tests as Predictors of Amputation
Authors: Garcia Diogo de Freitas Valeiro , de Sá Rafael Richard Clorado , de Oliveira Bernini Celso , Rasslan Samir
Published: June 2013

The decision of either preserving a member or primary amputation (PA) in severe extremity trauma, especially in the presence of fractures, vascular injuries or serious injuries of soft tissues has always been a challenge for the trauma surgeon. The initial assessment with objective criteria like indexes, such as the Mangled Extremity Severity Score (MESS) or the PSI, can aid in the differentiation of members that can be saved or should be amputated primarily. We report on the design and preliminary results of our ongoing prospective study analyzing laboratory test as predictors of amputation in severe lower limb trauma.

Materials and methods

All patients treated in our emergency department with severe lower limb trauma and open fractures (classified as Gustilo III) were included in this study. We collected blood for laboratory test of all patients at admission. All injured limb were photographed for posterior analysis and MESS classification.

Results

From March 15, 2012, to June 10, 2012, n = 20 patients were included in our study. PA was performed in eight (40%) and preserving procedures (PP) in 12 (60%). Mean age was 30 in PP group and 40.5 in PA. Mean systolic pressure at the emergency room was 130 mm Hg in PP and 107 mm Hg in PA. MESS index was calculated for all patients and the means were 5 for the PP group and 8 for the PA group. Laboratory test of the two groups were compared and statistically analyzed. Acidosis, arterial lactate levels and hemoglobin levels at admission had a statistical difference between the two groups: pH = 7.36 PP vs 7.18 PA (p = 0.001); lactate: PP = 25 vs PA = 63 (p < 0.001); hemoglobin: PP = 13.6 vs PA = 7.85 (p = 0.03).

Conclusion

Laboratory results of tests collected during initial assessment of patients with severe lower limb trauma are different between those submitted to PA or a PP.

How to cite this article

Garcia DFV, de Sá RRC, Bernini CO, Rasslan S . Preliminary Results of a Prospective Study on Severe Lower Limb Trauma: Analysis of Laboratory Tests as Predictors of Amputation. Panam J Trauma Critical Care Emerg Surg 2013;2(1):58-61.
Historic maps as a data source for socio-hydrology: a case study of the Lake Balaton wetland system, Hungary
Authors: Zlinszky A. , Timár G.
Published: June 2013

Abstract. Socio-hydrology is the science of human influence on the water cycle and the influence of the water cycle on human social systems. This newly emerging discipline inherently involves a historic perspective, often focusing on time scales of several centuries. While data on human history is typically available for this time frame, gathering information on the hydrological situation during such a period can prove difficult: measured hydrological data for such long periods are rare, while models and secondary datasets from geomorphology, pedology or archaeology are typically not accurate enough over such a short period. In the first part of this study, the use of historic maps in hydrology is reviewed. Major breakthroughs were the acceptance of historic map content as valid data, the use of preserved features for investigating situations earlier than the map, and the onset of digital georeferencing and data integration. Historic maps can be primary quantitative sources of hydro-geomorphological information, they can provide a context for point-based measurements over larger areas, and they can deliver time series for a better understanding of change scenarios. In the second part, a case study is presented: Water level fluctuations of Lake Balaton were reconstructed from maps, levelling logs and other documents. An 18th century map system of the whole 5700 km2 catchment was georeferenced, integrated with two 19th century map systems and wetlands, forests and open water digitized. Changes in wetland area were compared with lake water level changes in a 220 yr time series. Historic maps show that the water level of the lake was closer to present-day levels than expected, and that wetland loss pre-dates drainage of the lake. The present and future role of historic maps is discussed. Historic hydrological data has to be treated with caution: while it is possible to learn from the past, the assumption that future changes will be like past changes does not always hold. Nevertheless, old maps are relatively accessible datasets and the knowledge base for using them is rapidly growing, and it can be expected that long-term time series will be established by integrating georeferenced map systems over large areas. In the Appendix, a step-by-step guide to using historic maps in hydrology is given, starting from finding a map, through georeferencing and processing the map to publication of the results.
Lack of Influence of Serum Magnesium Levels on Overall Mortality and Cardiovascular Outcomes in Patients with Advanced Chronic Kidney Disease
Authors: Ortega Olimpia , Rodriguez Isabel , Cobo Gabriela , Hinostroza Julie , Gallar Paloma , Mon Carmen , Ortiz Milagros , Herrero Juan Carlos , Di Gioia Cristina , Oliet Aniana , Vigil Ana
Published: June 2013

Background. Low serum magnesium has been associated with an increased cardiovascular risk in the general population and in dialysis patients. Our aim was to analyze the influence of serum magnesium on overall mortality and cardiovascular outcomes in patients with advanced CKD not yet on dialysis. Methods. Seventy patients with CKD stages 4 and 5 were included. After a single measurement of s-magnesium, patients were followed a mean of 11 months. Primary end-point was death of any cause, and secondary end-point was the occurrence of fatal or nonfatal CV events. Results. Basal s-magnesium was within normal range (2.1±0.3 mg/dL), was lower in men (P=0.008) and in diabetic patients (P=0.02), and was not different (P=0.2) between patients with and without cardiopathy. Magnesium did not correlate with PTH, calcium, phosphate, albumin, inflammatory parameters (CRP), and cardiac (NT-proBNP) biomarkers but correlated inversely (r=−0.23; P=0.052) with the daily dose of loop diuretics. In univariate and multivariate Cox proportional hazard models, magnesium was not an independent predictor for overall mortality or CV events. Conclusions. Our results do not support that serum magnesium can be an independent predictor for overall mortality or future cardiovascular events among patients with advanced CKD not yet on dialysis.
Food Insecurity Experiences Predict Children’s Fruit and Vegetable Consumption in the USA
Authors: Howard Larry L.
Published: June 2013

This research analyses the longitudinal relationships between household food insecurity (very low and low food security) experiences and children’s consumption (servings/week) of fruit, green salad, carrots, potatoes, and other types of vegetables. Using a panel of 5,670 children aged 10–13 years who were first observed in spring 2004 and then again in spring 2007 at age 13–16 years, the main findings are as follows: first, children experiencing low food security consume significantly () more fruit per week. In contrast, children experiencing very low food security consume significantly more carrots and potatoes per week, and estimates based on gender-stratified models indicate that the association is strongest among girls. Second, activity patterns are significantly related to children’s dietary patterns; physical exercise is positively associated with fruit, green salad, carrot, and other vegetables consumption, while television watching is positively associated with potato consumption. Overall, the findings suggest that children living in food insecure home environments consume a greater number of servings of fruits and vegetables per week, relative to children living in food secure home environments.
Ecophysiological aspects of nectar reabsorption
Authors: Stpiczyńska Małgorzata , Nepi Massimo
Published: June 2013

A number of approaches, both direct and indirect, have shown that nectar is reabsorbed by numerous plant species, irrespective of the age or sex of the flower. Furthermore, reabsorption occurs regardless of whether or not the flower has been pollinated. Reabsorption helps to maintain concentration of nectar and their viscosity and thereby encourages continued visits by pollinators. Conversely, the capacity to vary concentration of nectar sugars may confer evolutionary advantage by encouraging visits by more than one kind of pollinator and this is particularly important in regions where there is a paucity of pollinators. A further important role of nectar reabsorption is the maintenance of the energy equilibrium of the plant. A number of studies have shown that nectar production involves considerable energy expenditure requiring as much as 37% of the plant's daily production of energy by photosynthesis. The increased metabolic costs incurred by the plant during nectar production and secretion can reduce its growth and reproduction during the following season. Reabsorption of nectar that has not been collected by pollinators enables the plant to conserve at least some of the energy reserved for the secretion of nectar. Sugars reabsorbed from nectar can be re-used for the development of fruit and ovules - processes which demand large quantities of sugar. Despite convincing evidence for the reabsorption of nectar, few detailed studies have addressed the transport and incorporation of reabsorbed sugars. One of the questions that remain to be answered is 'What is the cellular basis for nectar reabsorption by the nectary?'
The evaluation of self-compatibility and crossability in the genus Pyrus based on the observation of pollen tubes growth
Authors: Antkowiak Wojciech , Wojciechowski Andrzej
Published: June 2013

Interspecific compatibility and self-compatibility in Pyrus communis, P. pyraster and P. salicifolia were evaluated. Degree of compatibility was determined by means of fluorescence microscope. Self-incompatibility evaluated on the basis of the pollen tubes growth showed that two cultivars of P. communis (Bera Hardy and Lukasówka) were self-compatible and the other three cultivars were self-incompatible. All ecotypes of P. pyraster are self-incompatible. In interspecific crosses full inter-incompatibility or unilateral self-incompatibility was observed.