bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving and developing sustainable methods for plant protein processing
Authors:   US Dept. of Agriculture, Liu Keshun
Published: October 2022

Sustainability is the balance among environment, equity, and economy.  We practice it to support ecological, human, and economic health and vitality, and to meet our own needs without compromising the ability of future generations to meet their own needs.  With growing world population, widening gap between developed and developing economies, depleting natural resources, and devastating climate change, there is an urgent need for individuals, corporations, and governmental bodies to do more on sustainability.  As oil chemists, we can all play important roles by choosing, selecting, and/or developing sustainable methods to process plant proteins into food or feed. Once these methods are adopted or used by others, a ripple effect is created, where an individual effort is transformed into the effort of a large community or even at an industrial level.  Although there are many innovative ways to achieve sustainability when oil chemists are at work, reducing uses of chemicals and natural resources (water, energy, etc.) and cost, and generating less or no wastes are the key strategies.  In this presentation, I discuss three processing methods I improved, contributed, or developed during last two decades, to illustrate how an individual chemist can contribute to sustainability.  The methods to be discussed include a method for making plant-based meat analogs which has been commercialized, a method for producing soft and water-stable aquafeed, which serves as a promising strategy to mitigate water pollution associated with aquaculture, and a low-resource method for making soy protein concentrate, which is being evaluated at Soybean Innovation Lab for fighting malnutrition in Sub-Saharan Africa.   Hopefully, we all can make efforts to provide sufficient proteins to all people regardless of their social and economic levels, while maintaining sustainability for benefiting current and future generations.
Conventional and novel technologies for extraction of protein and their impact on structure and functionality as ingredient
Authors:   Iowa State University (ISU), Lamsal Buddhi , Rahman Md Mahfuzur ,   Kraft Heinz Food Company
Published: October 2022

Proteins possess their techno-functionalities by virtues of their state of being, i.e., their molecular makeup and structure, which in turn, is affected by the technologies employed to extract them from the matrices they belong to. This is true for both plant proteins and cell-based proteins. While pH-modulated solubility based aqueous extraction, followed by isolation, is the overwhelming method for plant protein preparations, other technologies, for example dry fractionation (separation based on density, air drag or electrostatic charges), enzyme-, microwave-, ultrasound-, pulsed electric energy- and high pressure-assisted extraction, subcritical water, reverse micelles extraction, and aqueous two-phase systems extraction have been researched for better yields and functionality.            Physical separation or dry fractionation preserves the molecular structure and protein possesses better techno-functional and sensory properties than conventional alkaline and acid-based methods. However, dry fractionation can produce only protein concentrate, not isolate. Although alkaline and acid-based methods can prepare to isolate efficiently, subsequent acid precipitation and drying methods form insoluble aggregates and enhance oxidation, which in turn, affect solubility and related functional properties as well as contribute to off-flavor.              This presentation will summarize such technologies for extraction, potential for sustainability and their impact on protein's structure and techno-functionalities such as solubility, foaming/emulsion, gelation etc. It will also present authors' recent research on ultrasound-assisted extraction of soy protein and changes in major isolate structure/ function.
High oleic palm oil: Uses and applications
Authors:   Danec SA, Munoz Juan Fernando
Published: October 2022

High oleic palm oil (HOPO) is the result of an agricultural innovation. A non-GMO palm, more resistant to diseases such as bud rot, with a higher oil yield per area than E.guineensis palm, was obtained. Its oil is mostly unsaturated; its oleic acid content is 10-15% higher compared to African palm oil. It has a higher content of beta-carotene (pro-vitamin A) and natural antioxidants such as tocotrienols and tocopherols (Vitamin E).HOPO can be refined by a special process that allows the oil to retain most of the nutritional components that are present in the crude oil. A refined red colored oil is obtained, with high beta-carotene and vitamins content, which can be fractionated to produce red oleins and stearins, for various applications where its color and nutritional value can be exploited.The objective of this conference is to share our experience in the use and commercialization of HOPO, highlighting its advantages in the formulation of edible oils and in industrial applications.High oleic red palm olein can be used as a cooking oil in households, imparting a pleasant reddish-gold color to food. Both red olein and stearin can be used in the production of baked goods, allowing these foods to retain part of the vitamins given by the oil, and as a source of natural beta-carotene.Traditionally refined high oleic palm olein, being more unsaturated than E. guineensis palm olein, is more resistant to crystallization in cold climates, which allows it to replace imported seed oils in edible oil formulas. Industries that produce snacks and fried foods also use this oil due to its high resistance to oxidation and its lower content of saturated fatty acids than traditional palm olein, facilitating the production of shortenings reduced in saturated fat, which is increasingly required by different industries in Latin America.
Developing High Yielding Soybean Varieties with Desirable Carbohydrate Fraction for Enhancing Nutrition
Authors:   University of Missouri, Nguyen Henry , Md Alikat Ali ,   University of Missouri, Lee Dongho ,   University of Missouri, Shi Haiying ,   University of Missouri
Published: October 2022

Soybean is the major seed oil and protein crop in the global market. The majority of soybean protein meal in the U.S. is used for feeding poultry and pigs. Raffinose family of oligosaccharides (RFOs) in soybean meal reduce feeding efficiency due to their anti-digestibility in monogastric animals. Current commodity soybeans do not have desirable carbohydrate fraction; thus, the development of new and improved varieties with reduced RFOs and increased sucrose is of great interest and adds value to the swine, poultry, and aquaculture industries. This presentation will summarize current progress in soybean breeding and the discovery of novel genetic resources which provide a great opportunity for improving the carbohydrate composition of US soybeans in all major maturity groups.
Purification of fumarated rosin
Authors:   Ingevity, Wang Bing
Published: October 2022

Fumarated rosin can be manufactured by Diel-Alder reaction of rosin, a by-product from kraft paper pulping method. There is always about 50% unreacted rosin left in the process. Recently, there is renewed demand for  higher purity of fumarated rosin, due to its multifunctional character. We have developed a new and scalable method to increase the purity of fumarated rosin. We will be discussing the details of this inventive method.
Evaluating Breeding and Management Solutions for Methionine Content in Soybean
Authors:   Virginia Tech, Singer William , Zhang Bo ,   Virginia Tech, Yu Dajun ,   Virginia Tech, Holshouser David ,   Virginia Tech, Huang Haibo ,   Virginia Tech, Brooks Keren ,   Virginia Tech, Rosso Maria ,   Virginia Tech, Reiter Mark ,   Virginia Tech
Published: October 2022

Soybean is widely recognized as a valuable crop and plant protein source due to its ideal amino acid profile. However, deficient methionine content in soybean seeds limits the nutritional utility. Therefore, a genome-wide association study (GWAS) utilizing 311 soybean accessions from maturity groups IV and V was performed alongside genomic prediction models to determine genetic underpinnings and breeding potential. Additionally, sulfur fertilization source and rate were evaluated for their impact on methionine content in soybean seeds. Across four environments, 23 novel single nucleotide polymorphisms (SNPs) were identified as being associated with methionine content, and average prediction accuracy (r2) ranged from 0.03 to 0.62 for genomic prediction models. Across six locations, soybean plots treated with ammonium sulfate (AMS) exhibited statistically increased methionine content when compared to other sulfur fertilizers. When combined, these results highlight the complex genetic and environmental controls for methionine content in soybean seeds and will positively contribute to protein quality improvement in soybean.
Supporting Argo-processing in Africa
Authors:   Cultivating New Frontiers in Agriculture, Eilitta Marjatta , Boyer Michael ,   AWT Management Services, Inc.
Published: October 2022

Improved oilseed processing has tremendous potential to improve nutrition, food security, and incomes in sub-Saharan Africa (SSA); however, processors face limitations that hinder their growth. For example, only 56% of soybeans produced in SSA are processed. The Soybean Innovation Lab survey highlighted  constraints to agro-processors' operations such as access to raw materials, cash flow, cost of entry and operation, and lack of equipment. But while agri-food processing in SSA is still lagging, Reardon (2015) observed an incipient €œquiet revolution€ in such midstream activities. Today, agro-processors in SSA demonstrate great potential to support economic growth€”from large, international companies, to medium/small enterprises supplying districts and towns, to micro enterprises serving communities. These enterprises also provide income-earning opportunities for women, youth, and vulnerable populations, directly impacting their food security and nutrition. To spur growth, the U.S. Agency for International Development (USAID) and other donors have invested in improving agro-processing in SSA. In Southern Africa, the American Oil Chemists' Society (AOCS), Soybean Innovation Lab, and USAID-funded Farmer-to-Farmer Program implemented by Cultivating New Frontiers in Agriculture (CNFA) are conducting a pilot to connect AOCS volunteers with processors. This presentation reviews the experiences with the partnership and describes how AOCS members can support African agro-processors.
Бризер малой амплитуды нелинейного уравнения Клейна-Гордона
Authors: Завьялов Д.В. , Конченков В.И. , Крючков С.В.
Published: October 2022

A technique for obtaining an approximate breather solution of the Klein-Gordon equation is presented. A breather solution of the equation describing the propagation of nonlinear waves in a graphene-based superlattice is investigated.
Вращательное и поступательное галопирование призм в воздушном потоке
Authors: Рябинин А.Н. , Бобу Ю.Э.
Published: October 2022

In experiments in a wind tunnel, oscillations of three prisms with a rectangular cross section are studied. The prisms are located perpendicular to the velocity vector of the incoming flow and are limited from the ends by end plates that prevent air flow. The elastic suspension allows body oscillation with six degrees of freedom. It turned out that under the action of the air flow, two modes of oscillation of prism realized: translational oscillations in the direction perpendicular to the generatrix of prismatic bodies and the flow velocity, and rotational oscillations around an axis that is parallel to the generatrix, passes through the center of the prism and is perpendicular to the velocity of the incoming air flow. The tension of the two springs included in the elastic suspension is measured by the strain gauge method during the oscillation. The calibration experiment makes it possible to link the amplitudes of spring tension oscillations and phase shift with the amplitudes of rotational and translational oscillations of prisms. It turned out that a prism with a height-to-width ratio of 0.22 in the flow is subject to rotational oscillations. An increase in the ratio of height to width to 0.36 leads to a decrease in the amplitude of rotational oscillations and the appearance of translational ones. The ranges of existence of rotational and translational oscillations overlap. A further increase in the ratio of height to width to 0.43 is accompanied by intensive translational galloping.
Моделирование ударно-волнового нагружения силикатов магния на примере форстерита
Authors: Маевский К.К.
Published: October 2022

The results of modeling the shock-wave loading of Mg2[SiO4] forsterite, which in this case is considered as a mixture of SiO2 quartz and MgO periclase, are presented. The model is based on the assumption that the components of the mixture under shock-wave loading are in thermodynamic equilibrium. The model allows us to reliably describe the phase transition region. The components of the investigated material are considered as a mixture of low and high pressure phases. Polymorphic phase transitions of quartz and periclase are taken into account in the calculation of forsterite in pressure range from 1 to 1000 GPa. The results are verified by experimental data obtained in dynamic experiments.
Модернизация ионного источника нейтронного генератора ИПФ РАН
Authors: Выбин С.С. , Изотов И.В. , Скалыга В.А. , Палашов О.В. , Миронов Е.А.
Published: October 2022

Using X-ray diffraction, there were determined the residual stresses on the surface of the AISI 310S stainless steel carrier tape used in manufacture of the second generation high temperature superconducting (2G HTS) wires at the National Research Center “Kurchatov Institute”, from delivery to deposition of the main buffer layer YSZ between the tape and the superconducting layer, and the residual stress in the buffer layer YSZ itself. The compressive stress of –0.8 GPa induced by rolling was found on the surface of the tape as-delivered. During processing, it varies from –0.5 to –1.1 GPa. At each stage, its depth distribution was found down to 10 μm, and the residual stresses caused by processing were determined. The residual stress in the YSZ layer deposited using the ABAD technology is compressive and amounts to –3.29 GPa. The layer has a defective single-crystal structure in type to radiation swelling with the unstressed lattice period of 5.1820 Å, 0.9% larger than in ordinary crystal. The results obtained are in agreement with the data of the earlier neutron diffraction study of residual stresses inside the carrier tape.
Эффект Джозефсона в нанографитовых пленках
Authors: Лебедев С.Г.
Published: October 2022

In nanographite films, for the first time the Josephson current at room temperature has been obtained when measuring the current–voltage characteristics. Sach measurement confirms the earlier observations in nanographite film the effects of weak superconductivity: zeroing of the temperature dependence at 650 K of constant voltage on the sample when it exposed to an alternating microwave voltage due to the inverse Josephson effect, as well as the observation of local areas with the structure of magnetic vortices in a magnetic force microscope at room temperature. The resulting critical current value of 0.8 µA is significantly lower than expected values ​​for the superconducting gap, as well as for pinning at the Bean–Levingston barrier. The measures for increasing the critical current is proposed.
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Невзаимность в распространении микроволн в системе [(CoFe)/Cu]/(glass)
Authors: Ринкевич А.Б. , Перов Д.В. , Миляев М.А. , Кузнецов Е.А.
Published: October 2022

The propagation of microwaves through the dielectric substrate/metal superlattice system [(CoFe)/Cu] has been investigated. The frequency dependences of transmission and reflection coefficients for the normal incidence of electromagnetic waves on the system in two opposite directions are measured. The effect of the substrate thickness on the magnitude of the microwave giant magnetoresistance effect during reflection and on nonreciprocity in the system is investigated. The influence of an external magnetic field on the nonreciprocity parameter is investigated. It has been established that under the conditions of nonreciprocity, the microwave giant magnetoresistance effect increases significantly when the wave is reflected.
Физико-механические характеристики биоматериалов-лоскутов для задач численного моделирования
Authors: Онищенко П.С. , Глушкова Т.В. , Костюнин А.Е. , Резвова М.А. , Барбараш Л.С.
Published: October 2022

A full-scale study of the physical and mechanical properties of a number of samples of commercial biomaterials-flaps was carried out. It is shown that all materials have a pronounced non-linearity of behavior, manifested in the presence of an initial gentle stress section with a subsequent increase in stiffness, however, there are quantitative differences in the length of these sections and, accordingly, in the final characteristics: tensile strength, elongation at break, elasticity. The results of numerical verification of the obtained coefficients of hyperelastic materials models showed high convergence with the results of field tests. Keywords: numerical modeling, physical and mechanical tests, hyperelastic material model, polynomial approximation.
Влияние знака дзета-потенциала наноалмазных частиц на морфологию композитов "графен--детонационный наноалмаз" в виде суспензий и аэрогелей
Authors: Рабчинский М.К. , Трофимук А.Д. , Швидченко А.В. , Байдакова М.В. , Павлов С.И. , Кириленко Д.А. , Кульвелис Ю.В. , Гудков М.В. , Шиянова К.А. , Коваль В.С. , Петерс Г.С. , Лебедев В.Т. , Мельников В.П. , Дидейкин А.Т. , Брунков П.Н.
Published: October 2022

Представлен новый способ использования детонационного наноалмаза с положительным и отрицательным знаком дзета-потенциала в качестве разделителя для аэрогелей на основе оксида графена. Показано, что дозированное добавление в суспензию оксида графена гидрозоля частиц детонационных наноалмазов позволило троекратно увеличить удельную поверхность образующегося аэрогеля по сравнению с аэрогелем оксида графена, и этот эффект значительнее при использовании наноалмазов с положительным дзета-потенциалом. Также показано, что полученные из оксида графена и детонационного наноалмаза с положительным дзета-потенциалом аэрогели обладают специфической морфологией: пластины оксида графена при этом скручены. Этот эффект обсуждается с точки зрения изменения среднего дзета-потенциала исходных смесей. Ключевые слова: двухкомпонентные системы, углеродные материалы, коллоидная химия.
Technical, Ethical, Legal, and Societal Challenges With Digital Twin Systems for the Management of Chronic Diseases in Children and Young People
Authors: Drummond David , Coulet Adrien
Published: October 2022

Advances in digital medicine now make it possible to use digital twin systems (DTS), which combine (1) extensive patient monitoring through the use of multiple sensors and (2) personalized adaptation of patient care through the use of software. After the artificial pancreas system already operational in children with type 1 diabetes, new DTS could be developed for real-time monitoring and management of children with chronic diseases. Just as providing care for children is a specific discipline—pediatrics—because of their particular characteristics and needs, providing digital care for children also presents particular challenges. This article reviews the technical challenges, mainly related to the problem of data collection in children; the ethical challenges, including the need to preserve the child's place in their care when using DTS; the legal challenges and the dual need to guarantee the safety of DTS for children and to ensure their access to DTS; and the societal challenges, including the needs to maintain human contact and trust between the child and the pediatrician and to limit DTS to specific uses to avoid contributing to a surveillance society and, at another level, to climate change.
Remote Monitoring of Colorectal Cancer Survivors Using a Smartphone App and Internet of Things–Based Device: Development and Usability Study
Authors: Ayyoubzadeh Seyed Mohammad , Baniasadi Tayebeh , Shirkhoda Mohammad , Rostam Niakan Kalhori Sharareh , Mohammadzadeh Niloofar , Roudini Kamran , Ghalehtaki Reza , Memari Fereidoon , Jalaeefar Amirmohsen
Published: October 2022

Background

Patients with colorectal cancer who undergo surgery face many postoperative problems. These problems include the risk of relapse, side effects, and long-term complications.

Objective

This study sought to design and develop a remote monitoring system as a technological solution for the postdischarge care of these patients.

Methods

This research was conducted in 3 main steps: system feature extraction, system design, and evaluation. After feature extraction from a systematic review, the necessary features were defined by 18 clinical experts in Iran. In the next step, the architecture of the system was designed based on the requirements; the software and hardware parts of the system were embedded in the architecture, then the software system components were drawn using the unified modeling language diagrams, and the details of software system implementation were identified. Regarding the hardware design, different accessible hardware modules were evaluated, and suitable ones were selected. Finally, the usability of the system was evaluated by demonstrating it over a Skype virtual meeting session and using Nilsen’s usability principles.

Results

A total of 21 mandatory features in 5 main categories, including patient information registration, periodic monitoring of health parameters, education, reminders, and assessments, were defined and validated for the system. The software was developed using an ASP.Net core backend, a Microsoft SQL Server database, and an Ionic frontend alongside the Angular framework, to build an Android app. The user roles of the system included 3 roles: physicians, patients, and the system administrator. The hardware was designed to contain an Esp8266 as the Internet of Things module, an MLX90614 infrared temperature sensor, and the Maxim Integrated MAX30101 sensor for sensing the heartbeat. The hardware was designed in the shape of a wristband device using SolidWorks 2020 and printed using a 3D printer. The firmware of the hardware was developed in Arduino with the capability of firmware over the air. In evaluating the software system from the perspective of usability, the system received an average score of 3.8 out of 5 from 4 evaluators.

Conclusions

Sensor-based telemonitoring systems for patients with colorectal cancer after surgery are possible solutions that can make the process automatic for patients and caregivers. The apps for remote colorectal patient monitoring could be designed to be useful; however, more research regarding the developed system’s implementation in clinic settings and hospitals is required to understand the probable barriers and limitations.
Co-design of a Virtual Reality Cognitive Remediation Program for Depression (bWell-D) With Patient End Users and Clinicians: Qualitative Interview Study Among Patients and Clinicians (Preprint)
Authors: Hernandez Hernandez Maria Elena , Michalak Erin , Choudhury Nusrat , Hewko Mark , Torres Ivan , Menon Mahesh , Lam Raymond W , Chakrabarty Trisha
Published: October 2022

BACKGROUND

Major depressive disorder (MDD) is the leading cause of global disability; however, the existing treatments do not always address cognitive dysfunction—a core feature of MDD. Immersive virtual reality (VR) has emerged as a promising modality to enhance the real-world effectiveness of cognitive remediation.

OBJECTIVE

This study aimed to develop the first prototype VR cognitive remediation program for MDD (“bWell-D”). This study gathered qualitative data from end users early in the design process to enhance its efficacy and feasibility in clinical settings.

METHODS

Semistructured end-user interviews were conducted remotely (n=15 patients and n=12 clinicians), assessing the participants’ perceptions and goals for a VR cognitive remediation program. Video samples of bWell-D were also shared to obtain feedback regarding the program. The interviews were transcribed, coded, and analyzed via thematic analysis.

RESULTS

End users showed an optimistic outlook toward VR as a treatment modality, and perceived it as a novel approach with the potential of having multiple applications. The participants expressed a need for an engaging VR treatment that included realistic and multisensorial settings and activities, as well as customizable features. Some skepticism regarding its effectiveness was also reported, especially when the real-world applications of the practiced skills were not made explicit, as well as some concerns regarding equipment accessibility. A home-based or hybrid (ie, home and clinic) treatment modality was preferred.

CONCLUSIONS

Patients and clinicians considered bWell-D interesting, acceptable, and potentially feasible, and provided suggestions to enhance its real-world applicability. The inclusion of end-user feedback is encouraged when developing future VR programs for clinical purposes.
Therapeutic Storytelling Intervention to Reduce Stress Level in Children with Acute Lymphoblastic Leukemia (ALL)
Authors: Oktari Siska , Iskandarsyah Aulia , Moeliono Marisa F.
Published: October 2022

Proses pengobatan melalui kemoterapi pada anak dengan Acute Lymphoblastic Leukemia (ALL) membutuhkan waktu yang lama dan merupakan proses yang menyakitkan. Hal ini menyebabkan munculnya stres pada anak. Penelitian ini bertujuan untuk menerapkan intervensi therapeutic storytelling untuk menurunkan tingkat stres anak. Partisipan dalam penelitian ini adalah 2 anak ALL berusia 10-12 tahun yang menjalani kemoterapi. Penelitian ini menggunakan metode eksperimen semu dengan desain penelitian subjek tunggal (small-n). Intervensi diberikan melalui proses mendongeng dengan buku cerita yang disusun oleh peneliti. Ceritanya melibatkan elemen positif (Cope, Hope, Inner Strengths, Love, dan Dream) yang membantu anak untuk mengidentifikasi elemen positif yang mereka miliki yang dapat mereka gunakan untuk melakukan tinjauan terhadap situasi yang dihadapi. Hasil penelitian menunjukkan bahwa terapi storytelling dapat menurunkan tingkat stres pada anak ALL.
Peran Empowering Leadership terhadap Intensi Turnover Karyawan Generasi Z di Indonesia
Authors: Pinandito Ignasius Satrio , Savira Alice Whita
Published: October 2022

Tujuan dari penelitian ini adalah untuk mengetahui peran empowering leadership terhadap intensi turnover pada karyawan Generasi Z. Hipotesis dalam penelitian ini adalah empowering leadership berperan negatif terhadap intensi turnover dengan mengendalikan variabel pendapatan. Jumlah partisipan penelitian ini adalah 180 partisipan dengan kriteria: tahun kelahiran 1995-2002, full-time employee, dan telah bekerja minimal selama 6 bulan dalam institusi/perusahaan saat ini. Alat ukur yang digunakan dalam penelitian ini adalah empowering leadership scale yang diadaptasi dari Amundsen & Martinsen (2014a) dan skala intensi turnover yang diadaptasi dari Landau & Hammer (1986). Koefisien reliabilitas Cronbach Alpha empowering leadership scale sebesar 0,815 pada dimensi dukungan otonomi, 0,852 pada dimensi dukungan pengembangan, dan 0,879 untuk seluruh dimensi (koefisien reliabilitas alpha berstrata). Koefisien Cronbach alpha intensi turnover sebesar 0,810. Penelitian ini juga melibatkan variable kontrol berupa pendapatan. Analisis data menggunakan hierarchial regression analysis. Hasil menunjukkan empowering leadership berperan negatif terhadap intensi turnover R2=0,059. Artinya, 5.9% variasi intensi turnover bisa dijelaskan oleh variabel empowering leadership. Sedangkan sisanya yakni 94,1% dijelaskan oleh variabel lain. Data deskriptif menunjukkan hubungan antara variabel demografis dan intensi turnover. Hasil menunjukkan terdapat hubungan antara pendapatan yang diterima oleh karyawan dan intensi turnover, sedangkan usia, jenis kelamin, lama bekerja, dan status perkawinan tidak memiliki hubungan yang signifikan dengan intensi turnover. Analisis tambahan juga menunjukkan hubungan antara masing-masing dimensi empowering leadership dengan intensi turnover.
Physical Stability and Antioxidant Activity of Pee-Off Gel Mask Ethanol Extract of Buas-buas Leaf (Premna serratifolia L.)
Authors: Puspita Weni , Puspasari Heny
Published: October 2022

This study aims to determine the physical stability and antioxidant activity of peel-off gel mask ethanol extract of buas-buas leaf (Premna serratifolia L.). The ethanol extract of buas-buas leaves was obtained by maceration using 70% ethanol solvent, then concentrated using a rotary evaporator to get a thick extract. Formulation EEDB into a peel-off gel mask with a concentration of each EEDB (FI: 1%, FII: 2%, FIII : 3%). The EEDB peel-off gel mask formula was tested for physical stability by cycling test method using a climatic chamber at a temperature of 40°C ± 2°C and 4°C ± 2°C for six cycles. The tests included organoleptic, homogeneity, viscosity, pH, spreadability, and drying time. An antioxidant test was carried out using the DPPH method. The results of the physical stability test on the three EEDB peel-off gel mask formulas (FI: 1%, FII: 2%, FIII: 3%) showed good physical stability because there was no significant difference during six storage cycles (P>0.05) with the results of the preparation have a characteristic aroma of oleum citri, brownish-green in color, have a thick, homogeneous texture, meet the requirements of pH, viscosity, spreadability, and drying time. The stability test results of the antioxidant activity of the peel-off gel mask EEDB in the three formulas showed no significant change (P>0.05). The antioxidant activity during six storage cycles with the highest average percent inhibition before and after the cycling test, namely in Formula III, was 77.20 ± 0.28%.
Effectiveness of Antibacterial Extract Bawang Suna (Allium schoenoprasum L.) against Methillicin-Resistant Staphylococcus aureus (MRSA) using Total Plate Count
Authors: Agustin Kania Claranisza , Fatmaria Fatmaria , Augustina Indria
Published: October 2022

Methicillin-Resistant Staphylococcus aureus (MRSA) infection can cause death which has caused the World Health Organization (WHO) in 2017 to issue a list of priority pathogens (one of which is MRSA) for the search for new antibiotic research. Bawang suna (Allium schoenoprasum L.) is believed to be able to inhibit the growth of the number of MRSA bacterial colonies because it contains saponins, alkaloids, flavonoids, tannins, triterpenoids, and steroids. The research was aimed to prove extract of bawang suna(Allium schoenoprasum L.) has effectiveness as an antibacterial to inhibit the growth of MRSA. True experimental design research design with cup count method using posttest only control design to compare the results of observing the number of MRSA bacterial colonies with and without treatment (control group) with serial dilution sampling technique serial dilution using a ratio of 1:5. The treatment used 1 ml an extract of bawang suna (Allium schoenoprasum L.) in the control group. 1 ml an extract of bawang suna (Allium schoenoprasum L.) gave a significant and closely related effect to inhibiting the growth of MRSA bacteria at a dilution level of 10-3 of 3288,50 + 1117,98, a dilution level of 10-4 of 379,25 + 33,75, and a 10-5 dilution rate of 42,00 + 8,68. The decrease in the number of MRSA bacterial colonies was due to the extract of bawang suna (Allium schoenoprasum L.) containing compounds: saponins, alkaloids, flavonoids, tannins, triterpenoids, and steroids that could prevent the growth of MRSA bacterial colonies. The extract of bawang suna (Allium schoenoprasum L.) as much as 1 ml using Total Plate Count (TPC) with serial dilution testing technique has a significant effect on dilutions of 10-3, 10-4, and 10-5 as an antibacterial to inhibit the growth of MRSA bacteria
Toxic Occupational Exposures and Membranous Nephropathy
Authors: Cremoni Marion , Agbekodo Sophie , Teisseyre Maxime , Zorzi Kevin , Brglez Vesna , Benzaken Sylvia , Esnault Vincent , Planchard Jo-Hanna , Seitz-Polski Barbara
Published: October 2022

Background and objectives

Membranous nephropathy is a rare autoimmune kidney disease whose increasing prevalence in industrialized countries pleads for the involvement of an environmental factor in the development of the disease. In addition, the predominance of men in membranous nephropathy, classically attributed to biologic or genetic differences between men and women, could also be due to different occupational exposures. To support this hypothesis, we sought to describe the toxic occupational exposures of patients with membranous nephropathy.

Design, setting, participants, & measurements

In this observational epidemiologic study, we compared the occupations and toxic occupational exposures of 100 patients with membranous nephropathy with those of the general population, consisting of two cohorts of 26,734,000 and 26,500 French workers. We then compared the characteristics of patients exposed to an occupational toxic substance with those of unexposed patients.

Results

Patients with membranous nephropathy worked more frequently in the construction sector than the general population (33% versus 7%, P<0.001). This difference remained significant by age and sex. They were also more frequently exposed to toxic substances, such as asbestos (16% versus 5%, P<0.001), lead (9% versus 1%, P<0.001), or organic solvents (37% versus 15%, P<0.001), than the general population. The predominance of men in the subgroup of patients occupationally exposed to toxic substances was not observed in unexposed individuals (organic solvents: 80% men versus 41%, P<0.001; asbestos: 90% men versus 55%, P=0.004). In addition, patients with phospholipase A2 receptor 1 (PLA2R1) epitope spreading were more frequently exposed to asbestos and organic solvents than patients without epitope spreading (32% versus 7%, P=0.02 and 74% versus 43%, P=0.02, respectively), with a dose-dependent effect.

Conclusions

Patients with membranous nephropathy were more frequently exposed to certain occupational toxic substances, such as asbestos and organic solvents, than the general population. This occupational exposure was more frequent in men and in patients with PLA2R1 epitope spreading.

Clinical Trial registry name and registration number:

Immunopathological Analysis in a French National Cohort of Membranous Nephropathy (IHMN), NCT04326218.

Podcast

This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2022_10_25_CJN02930322.mp3.
How the Routine Use of Patient-Reported Outcome Measures for Hemodialysis Care Influences Patient-Clinician Communication
Authors: Schick-Makaroff Kara , Wozniak Lisa A. , Short Hilary , Davison Sara N. , Klarenbach Scott , Buzinski Robert , Walsh Michael , Johnson Jeffrey A.
Published: October 2022

Background and objectives

Patient-reported outcome measures invite patients to self-report aspects of their quality of life and have been reported to enhance communication with clinicians. We aimed to examine how routine use of patient-reported outcome measures in in-center hemodialysis units influenced patient-clinician communication.

Design, setting, participants, & measurements

A concurrent, longitudinal, mixed-methods approach was used. We used data from a cluster randomized controlled trial of 17 hemodialysis units in northern Alberta that introduced a patient-reported outcome measures intervention. Patient-clinician communication was assessed using a modified Communication Assessment Tool. Using interpretive description, we explored patients’ and nurses’ perceptions of communication pertaining to routine patient-reported outcome measure use. Through purposeful sampling, we interviewed ten patients and eight nurses and conducted six observations in the dialysis units, which were documented in field notes. We reviewed 779 patient responses to open-ended survey questions from randomized controlled trial data. Qualitative data were thematically analyzed.

Results

Overall, patient-reported outcome measure use did not substantively improve patient-clinician communication. There was a small positive change in mean total Communication Assessment Tool scores (range, 1–5) from baseline to 12 months in patient-reported outcome measure use units (0.25) but little difference from control group units that did not use patient-reported outcome measures (0.21). The qualitative findings provide in-depth insights into why patient-reported outcome measure use did not improve patient-clinician communication. The purpose of patient-reported outcome measure use was not always understood by patients and clinicians; patient-reported outcome measures were not implemented as originally intended in the trial, despite clinician training; there were challenges using patient-reported outcome measures as a means to communicate; and patient-reported outcome measure use was perceived to have limited value.

Conclusions

While patient-reported outcome measures use did not improve patient-clinician communication, qualitative data suggest implementation challenges, including limited clarity of purpose and perceived limited value, that may have limited the effectiveness of the intervention.
A Valuation Proposal for the Historic Center of Pirenópolis using the Travel Cost Method
Authors: Carvalho Dr. Ronaldo do Nascimento , Castro Dr. Joana D'arc Bardella , Santos Dr. Jean Carlos Vieira , Rosa Camilla Alonso Lôbo , Costa Pedro Almeida , Vila Verde Dr. Giuliana
Published: October 2022

The city of Pirenópolis offers tourism, allowing access to several attractions, such as the Historical Center and its natural landscapes. Therefore, this article presents a proposal for environmental valuation called the Travel Cost Method. The tourist activity in the city stands out as an essential source of income and revenue for the municipality. Commercial establishments linked to tourism in Pirenópolis represented 42.3% of the Ouro e Cristais region until 2018. With this, the methodology used in the work is quantitative-qualitative, where the researchers were based both on doctrine, through bibliographic research, and in self-designed questionnaires to determine the valuation of the studied place. Taking these results as a reference, it is considered that the Survey's evaluation showed significant satisfaction in the sense of the largest number of questions raised, with only the Transit option being the only one that did not reach the maximum score of the reference. Therefore, it is concluded that the appropriation of landscapes can present future risks to the environment because it is not enough to preserve but constantly to be renewed in the matter of public policies, which should be contemplated in conservation actions.
The Effect of the Circular House Strategy on Acquiring Geographical Concepts for Fourth-grade Literary Students and Developing Their Effective Communication
Authors: Al-Fahdawi Nazim Jawad Ali Firas , Al-Fahdawi Abdul Halim Mohammed Obaid Saeed
Published: October 2022

he current research aims to identify (the effect of the circular house strategy in acquiring geographical concepts for fourth-grade literary students and developing their effective communication). For girls, this sample was randomly divided into two groups, one of them was an experimental group that included (32) students who studied geography using the circular house strategy, and the other was a control group consisting of (33) students, who studied the same material in the traditional way. The variables are: (the chronological age of the students calculated in months, the academic level of the parents, the effective communication scale). The Republic of Iraq, the researchers also prepared model teaching plans for both groups. The researchers adopted two tests to measure their research variables. The first test was The test for accquiring geographical concepts consist of (13) items and its validity, stability and were verified, as well as statistical analyzes of its paragraphs. The control group in the concept acquisition test and the effective communication scale.
Влияние режимов многоимпульсного тока и теплового нагрева на механическое поведение при растяжении титана Grade 4
Authors: Корольков О.Е. , Столяров В.В.
Published: October 2022

Показано влияние длительности импульса и плотности многоимпульсного тока, а также теплового нагрева на деформационное поведение и механические свойства при растяжении технически чистого титана Grade 4. Сравниваются вклады теплового и электропластического эффекта в снижение напряжений течения при одинаковой температуре. Отмечается, что наблюдаемые эффекты реализуются в отсутствие структурных изменений при выбранных режимах воздействия.
Цифровая трансформация метрологии и метрологическое обеспечение в промышленности
Authors: Пронякин В.И. , Комшин А.С.
Published: October 2022

Представлены современные подходы цифровизации в промышленности и метрологии. Обсуждается проблема обеспечения качества отечественной машиностроительной и приборостроительной продукции, связанная с метрологическим обеспечением оценки соответствия продукции в производстве. Поставлен вопрос об отношении к метрологии и метрологическому обеспечению в промышленности. Рассматриваются вопросы неоднозначности терминологии в части метрологического обеспечения в нормативной документации.
HUBUNGAN SUKROSA DENGAN PRODUKSI LATEKS PADA TANAMAN KARET KLON PB 260 UMUR BERBEDA
Authors: Purwaningrum Yayuk , Asbur Yeni , Rahayu Murni Sari , Rambe Rahmi Dwi Handayani , Kusbiantoro Dedi , Nasution Khairunisyah
Published: October 2022

PB 260 atau dikenal dengan klon quick starter memiliki masa gugur daun lebih cepat dibandingkan dengan jenis klon lainnya. Pada penelitian ini bertujuan untuk menentukan hubungan antara perbedaan umur tanaman karet klon PB 260 dengan kadar kandungan sukrosa lateks yang dihasilkan. Penelitian ini dilakukan di PT. Perkebunan Nusantara III (Persero) Afdeling I, Bandar Betsy, Kabupaten Simalungun, pada ketinggian 900 m di atas permukaan laut. Tanaman yang diamati yaitu jenis klon PB 260 dengan waktu tahun tanam 2004, 2005, 2010 dan 2011 yang memiliki lingkar batang 60-75 cm dan dihitung dengan tinggi 130 cm di atas permukaan tanah. Metode penelitian ini ditentukan dari analisis uji korelasi dan regresi. Hasil penelitian diperoleh hubungan antara peran dari kandungan sukrosa terhadap produksi lateks klon PB 260 diperoleh waktu tahun tanam 2004 yang kecil hanya 3%, tahun tanam 2005 sebesar 14%, 2010 dan 2011 sangat kecil hanya 0,3%.
KONDISI FISIOLOGIS DAN PRODUKSI TANAMAN KARET YANG TERSERANG PESTALOTIOPSIS DENGAN PEMBERIAN PUPUK DAN APLIKASI FUNGISIDA
Authors: Febbiyanti Tri Rapani , Tistama Radite
Published: October 2022

Penyakit gugur daun (PGD) Pestalotiopsis menyebabkan pengguguran daun yang terus-menerus terutama jika patogen menyerang pada periode pembentukan daun muda (flush) setelah gugur daun alami. Pembentukan daun baru yang berulang menyebabkan gangguan fisiologis pada tanaman karet, terutama pada tanaman muda. Pada tanaman belum menghasilkan, pembentukan dan pengguran daun muda yang berulang yang disebabkan oleh penyakit gugur daun seringkali menyebabkan stres fisiologi dan perkembangan lilit batang terhambat sehingga memperlambat matang sadap. Pada tanaman menghasilkan, pembentukan dan pengguguran daun muda yang berulang akibat PGD Pestalotiopsis ini mengakibatkan kerapatan kanopi dan penurunan produksi yang signifikan sehingga perlu diketahui kondisi fisiologis tanaman akibat PGD Pestalotiopsis melalui aplikasi pupuk dan fungisida. Tujuan penelitian ini adalah mengetahui pengaruh pemberian pupuk dan aplikasi fugisida terhadap kondisi fisiologi dan produksi tanaman yang terserang PGD Pestalotiopsis. Penelitian menggunakan klon GT 1 yang dilaksanakan di Kebun Percobaan Pusat Penelitian Karet Sembawa, Sumatra Selatan. Hasil pengamatan di lapangan terlihat, defoliasi terjadi mulai bulan Januari hingga Mei 2019, pengguguran tajuk lebih dari 60%, sehingga tajuk yang tertinggal di pohon hanya sekitar 30%. Pada bulan Mei 2020 pengguguran mencapai 70% pada perlakuan kontrol. Tingginya intensitas penyakit ini karena kepekatan spora patogen di udara masih tinggi dan sumber infeksi dari inang lain juga masih banyak. Keparahan serangan sangat dipengaruhi kondisi iklim, tahun dengan iklim basah lebih tinggi tingkat serangannya. Hasil lateks diagnosis (LD) pada bulan Juni 2020 menunjukkan kondisi aktivitas metabolisme lateks relatif sama antar perlakuan yaitu optimal dengan maksimal. Hasil produksi memperlihatkan peningkatan setelah Januari 2020 pada semua perlakuan, sedangkan pada hasil perlakuan kontrol sedikit mengalami peningkatan yang memiliki korelasi dengan persentase kanopi. Penurunan kanopi pada Februari 2020 tidak banyak berpengaruh terhadap produksi, bahkan penurunan kanopi mayor di April 2020 belum menurunkan hasil karet. Pengurangan hasil karet terjadi Juni 2020 pada saat gugur daun alami terjadi dan mencapai produksi terendah Agustus sampai September 2020 di saat daun muda mulai muncul. Produksi karet sudah mulai meningkat setelah satu bulan pembentukan daun, dimana pada umur daun ini fotosintesis sudah mulai pulih dan sukrosa sudah didistribusikan dalam jumlah yang cukup ke pembuluh lateks (latisifer). Aplikasi fungisida dengan cara fogging memberikan pengaruh luas kanopi dan produksi yang lebih tinggi dibandingkan perlakuan lainnya.
IMPROVEMENT OF PHYSIOLOGICAL CONDITION AND LATEX FLOW OF RUBBER CLONES AFFECTED BY TAPPING PANEL DRYNESS IN RESPONSE TO COMBINATION NAPHTHALENE ACETIC ACID, ASCORBIC ACID, AND NUTRITION TREATMENTS
Authors: Lubis Ade Fipriani , Tistama Radite
Published: October 2022

The TPD incident is one of the factors causing rubber estates to lose their production. The objective of this research was to arrange formulation for recovering of tapping panel dryness (TPD) chases, especially on PB 260 and IRR 42 clones. The experiment was divided into two experiments, that were arranged into a split plot design with two treatment factors, first the main plots of rubber plant clones (PB 260 and IRR 42), and second different NAA concentrations in the step 1. The best combination of the first experiment was added with different concentrations of ascorbic acid in the research experiment II. The physiological variables observed were sucrose, inorganic phosphate, thiol, latex production, and biochemical variables were SOD, APX, and POD enzyme activities. The TPD-affected plant could produce latex under treatment of NAA and nutrient for six months NAA 10 ppm treatment significantly affected on Pi content and had positive effect on latex production. Treatment of ascorbic acid also increased production in rubber plants and affected on POD and SOD activities. There were differences respond between high metabolism clone PB 260 and low metabolism clone IRR 42 to combination of NAA, nutrient, and ascorbic acid treatment.