bluuebunny/crossref_metadata_2025 huggingface dataset:
How to predict the temperature of the CMB directly using the Hubble parameter and the Planck scale using the Stefan-Boltzman law
Authors: Haug Espen , Wojnow Stephane
Published: November 2023

Based on recent progress in quantum gravity and quantum cosmology we are presenting also a way to estimate the temperature in cosmos, the Hubble sphere, from a relation between the Planck temperature and the Hubble scale. Our analysize predict the Hubble sphere temperature of 2.72k with the one standard deviation confidence interval between 2.65k and 2.80k, which correspond well with the measured temperature observed from the cosmic microwave background (CMB) of about 2.72k. This add evidence to that there is a close connection between the Planck scale, gravity and the cosmological scales as anticipated by Eddington already in 1918.
ST-ASDNET: A BLSTM-FCN-Transformer basedASD Classification Model for Time-series fMRI
Authors: Deng Xin , Zhang Lianhua , Liu Rui , Chen Zhuofeng , Xiao Bin
Published: November 2023

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that causesrepetitive and stereotyped behavior and social dysfunction. Early diagnosis andintervention can improve the effectiveness of treatment. However, the currentdiagnostic methods of ASD still use the subjective symptom criteria of clinicalobservation, which is time-consuming and labor-intensive. In recent years, theemergence of functional magnetic resonance imaging (fMRI) neuroimaging techniques has facilitated the identification of potential biomarkers for the diagnosisof ASD. In this study, we developed a deep learning framework called Spatio-Temporal Autism Spectrum Disorder Network (ST-ASDNet) to distinguish ASDsfrom normal controls (NCs) as well as to distinguish ASD subtypes based onthe fMRI data. Specifically, two modules: 1) bidirectional long and short-termmemory Transformer (BLSTM-Transformer) and 2) full convolutional networkTransformer (FCN-Transformer) are proposed to obtain the spatial and the temporal characteristics of the fMRI data, respectively. Additionally, we explored theinfluence of different brain atlas for preprocessing the fMRI data to recognize theASDs. The study verifies that a more detailed division of brain regions is helpfulfor the recognition of ASDs. The proposed model is evaluated on the Craddock200 (CC200) atlas and the Automated Anatomical Labeling (AAL) atlas with the robust accuracy of 70.26% and 67.80%, respectively. The effect of the proposed model is competitive in diagnosing ASD compared with other methods,which could provide a useful and effective way to assist the clinical diagnosis.
Numerical investigation of the autothermal steam-air-blown gasification of a low-grade fuel in non-stationary regimes
Authors: Abaimov Nikolay , Ryzhkov Alexander , Alekseenko Sergey , Batmunkh Sereemter , Osipov Pavel
Published: November 2023

A numerical investigation of the initial stage of the non-stationary autothermal conversion of low-grade micronized coal with cold air and steam supplied separately to an entrained-flow setup with a capacity of 0.1 MW was carried out. The syngas composition CFD model and the nonlinear dynamics of temperature change over time were numerically validated. The CFD study showed that in partial gasification mode, the degree of carbon conversion in the setup was 24–26%, H2/CO = 0.29–0.43, which corresponds to work in the primary furnace mode. Increasing the H2/CO ratio by 1.5 times significantly reduces emissions of nitrogen oxides from the gasifier and the GTU combustion chamber. CFD simulation shows that the non-stationary conversion process generally proceeds in three stages, the localization of which depends on the input parameters and design parameters. The introduction of a weakly superheated axial steam jet creates asymmetric hydrodynamic, structural, chemical and temperature inhomogeneities in the second stage. The CFD calculations made it possible to determine the sensitivity of conversion rates for the setup’s operating parameters and design.
The Association of KRAS Mutation and Primary Tumor Location with Recurrence in Colorectal Liver Metastases Undergoing Radiofrequency Ablation
Authors: Jiang Binbin , Wang Jichen , Yan Kun , Zhang Zhongyi , Wang Song , Wu Wei , Yang Wei , Chen Minhua
Published: November 2023

Purpose
KRAS mutation and Primary tumor location are important factors affecting the prognosis of patients with colorectal liver metastases (CLM). However, some studies showed there may be an interaction between the two. We sought to investigate the association of KRAS mutations with recurrence in patients with CLM undergoing radiofrequency ablation (RFA) according to the primary tumor location.
Methods
CLM patients with a known KRAS gene status who underwent RFA were enrolled from January 1, 2012 to December 31, 2018. Clinicopathological data, recurrence, and survival dates were evaluated retrospectively.
Results
164 patients (mean age: 58.0 ± 9.8 years, range: 34–83) who underwent percutaneous RFA of 325 CLM (mean sizes: 2.2 ± 1.0 cm, range: 0.7–5.0) were included in the study; 89 (54.3%) cases were KRAS wild-type and 75 (45.7%) cases had KRAS mutation. Of the patients, 22.0% (36 of 164) had local tumor progression (LTP), and 23 of 75 patients (30.7%) in the KRAS mutation group had LTP, which was significantly higher than in patients with KRAS wild-type (13 of 89 patients (14.6%)) (p = 0.013). Of the 126 (76.8%) patients with recurrence after RFA, 101 (61.6%) had intrahepatic recurrence, while 88 (53.7%) had extrahepatic recurrence. Among patients with left-sided colorectal cancer (CRC), intrahepatic recurrence rates were higher among patients with KRAS mutation than among patients with the wild type KRAS (77.2% vs 52.5%, p = 0.003); the median intrahepatic recurrence-free survival (RFS) was worse in KRAS mutation patients (25 vs 15 months, P = 0.007). In patients with right-sided CRC, there was no significant difference in intrahepatic recurrence between the KRAS wild-type and KRAS mutation groups (P＞0.05). Further, KRAS gene had no impact on extrahepatic recurrence irrespective of the primary tumor site. In the multivariable analysis, KRAS mutation and positive lymph nodes remained independently associated with a worse RFS among patients (HR: 1.526, 95% confidence interval [CI]: 1.056–2.207, P = 0.025; HR: 1.602, 95% CI: 1.008–2.545, P = 0.046).
Conclusions
KRAS status is associated with recurrence of CLM after RFA depending on primary tumor location.
Investigation on residual stress formation mechanism considering cutting energy in milling of aluminum alloy
Authors: Zheng Youyi , Yuzhao Tian , Ma Junjin , Zhang Faping , Cui Xiaobin , Ren Lei
Published: November 2023

Aluminum alloy has the characteristics of good corrosion resistance and high strength, so aluminum alloy workpiece is widely used in the aerospace field. However, in milling, the surface of the aluminum alloy workpiece generates residual stress due to the coupling of force and heat, which seriously affects the fatigue performance of the workpiece. To investigate the residual stress formation mechanism, an analyzed model of machining-induced residual stress considering energy conversion in milling process was proposed. In this process, the milling force prediction model is established. Then, an effective cutting work model is established based on the milling force model. After that, the strain energy density of the machined surface layer was analyzed and the strain energy solution model was established. Subsequently, the prediction models of mechanical stress, thermal stress and residual stress are established respectively, and the residual stress data are brought into the strain energy model to obtain the strain energy. Afterwards, the functional transformation relationship between effective cutting work and strain energy storage per unit time is analyzed. Finally, several milling experiments were carried out to verify the predicted milling force and residual stress. Experimental results show that errors between the predicted results and the experimental results are about 5 % and 15 %, respectively, and the functional transformation results show that the stored strain energy per unit time increases with the increase of the effective cutting work.
Autism and Suicide: Strategies to Dovetail Emerging Evidence in Child and Adolescent Suicide Risk Assessments
Authors: Gupta Mayank , Gupta Nihit , Petti Theodore
Published: November 2023

Background: This narrative review provides readers with a greater awareness of the increasing prevalence of diagnosed autism spectrum disorder (ASD) in psychiatric clinical settings and the high risk that ASD and autistic traits in the population place the affected individuals at heightened risk for suicidality and suicide.
Methods: It represents a comprehensive, systematic literature review. supplemented with reverse citations to assure updated information. By title and abstract 456 articles were identified 456 and 71 articles met the inclusion criteria. Out of those, 50 articles were used for initial review and 15 were added later, manually or through reverse citations.
Results: Results indicate that associated suicidal thoughts and behaviors (STB) with ASD, many concomitants comorbid mental health conditions ASD, and suicide risk factors that overlap with ASD symptoms are not clearly understood. Higher rates of STB and suicide have been identified across the age spectrum with ASD/high autistic traits compared to those from the general population in age/sex-matched comparison groups. Increased risk of STB in higher functioning ASD is emphasized. Interpersonal conflict and depression are significant risk factors as are comorbid borderline personality, bipolar disorder, anxiety, and obsessive-compulsive disorders.
Conclusions: Multiple diagnostic challenges are considered that support the need for more focused research in this area, better, more ASD-related screening instruments that address the unique features of ASD-related psychopathology, and improved training for clinicians in screening and preventive efforts for enhanced competence and greater comfort in dealing with STB in those with autistic traits and ASD.
Understanding preservice teachers’ perspectives on challenges experienced during work integrated learning
Authors: Ndebele Clever , Legg-Jack Dagogo William , T Tabe Hennades
Published: November 2023

The demands on educational institutions in the 21st century are constantly changing, necessitating adapted teaching, and learning techniques both within and outside of the classroom. Central to these evolutionary changes is the teacher who is expected to initiate innovative teaching strategies that often come with a variety of challenges. This requires preservice teachers to consequently complete extensive work-integrated learning (WIL) for a defined period as part of their initial teacher training. The article sought to ascertain the challenges, faced by preservice teachers during WIL using the situated learning theory, which emphasises the relevance of the integration of new ideas and human actions in dealing with ongoing environmental challenges. The methodology of the study is built on an interpretive paradigm, employing a qualitative case study design. Data was collected through interviews from Fourteen B.Ed. Honours preservice teachers were selected through a non-probability sampling method, known as purposive sampling. Data analysis was done thematically and with the use of Atlas ti 9. The study found some degree of complexities and inter-relationship between the preservice teachers challenges and their inability to deliver content. Exceptionally, however, some challenges like the delegation of responsibilities, pedagogy and especially transportation issues show high-level association with an implication to WIL for preservice teachers. The study however makes some crucial recommendations to policy and practice, which include an expansion and emergency modification in teaching pedagogy to incorporate technology, mandatory professional training and induction programmes for mentors and the need to enhance the environmental approach to teaching
Epistemological access: a case of academic development programmes at a university of technology
Authors: Samosamo Mothusi George , Divala Joseph Jinja
Published: November 2023

South Africa has made significant progress in expanding access to higher education since the end of the apatheid era. This gave opportunities to a larger portion of the population to pursue higher education studies, especially those from previously disadvantaged communities. The growth in student enrollment has not always correlate with academic success. High levels of failure and dropout rates amongst first-year students are a common challenge across universities. This implies that the challenges related to epistemic access at universities persist. To address these challenges, universities implemented academic development programmes providing targeted interventions and fostering a supportive learning environment that can help bridge the gap between formal access to universities and epistemic access. The study that informs this paper sought to explore how academic development programmes enable epistemological access to first-year students. This study employed a qualitative methodological approach and adopted a purposive sampling strategy to select the participants. The study interviewed twenty mentors participating in an academic development programme (mentorship) at a University of Technology. The findings highlights the role of academic development programme (mentorship programme) in enabling students to transition from unfamiliarity to familiarity within their chosen field of study, leading to an epistemic shift that alters their epistemological level. These findings can contribute to the broader discussions and advancements in higher education pedagogy by highlighting the importance of and understanding the mechanisms behind the mentorship programme. The implications of this study on higher education is to inform the design and implementation of effective initiatives that foster epistemological growth and empower students to engage with disciplinary knowledge more effectively
Spatiotemporal changes of land use in response to runoff and sediment yield for environmental sustainability in the upper Blue Nile Basin, Oromiyaa, Ethiopia
Authors: Tumsa Bekan Chelkeba , Feyessa Fekadu Fufa , Tullu Kiyya Tesfa , Guder Abebe Chala
Published: November 2023

Modeling and mapping hydrological responses of runoff and sediment yield to spatiotemporal land use changes are crucial concerning environmental sustainability. The research was aimed at quantifying the spatiotemporal effects of land use on runoff and sediment yields using three land use satellite images and the SWAT+ model. The increase in agriculture, settlement, and decreasing forest goes to the possibility of increasing sediment yield and runoff by 53.2 and 56.5%, respectively, affecting ecosystems. The areas vulnerable to high runoff were found at the lower and middle reaches with the annual average runoff of 10,825.1, 11,972.9, and 13,452 mm for each respective scenario. On the other hand, most of the soil erosion-prone areas designated as severe in the second and third scenarios were covered by agriculture and shrubland, with annual sediment yields of 301.5 and 267.5 tons, respectively. Deforestation for agricultural expansion has a significant role in environmental degradation, as forests play an irreplaceable role in ecological resilience. Generally, the dominant land uses that instigate soil erosion, runoff, and sediment yield are agriculture, shrubland, and deforestation. The simulation of runoff and sediment yield in response to land use change using the SWAT+ model is more scientifically reliable and acceptable.
ASSISTÊNCIA FISIOTERAPÊUTICA EM GRUPO PARA INDIVÍDUOS COM DOENÇA DE PARKINSON: UM RELATO DE EXPERIÊNCIA
Authors: De Oliveira Bezerra Ana Beatriz , Nunes Barbosa Santos Brenda , Evangelista Rodrigues da Silva Kelly , Cavalcante do Nascimento Jessica Rayane , Maria da Costa Lariza , De Moura Freitas Luana Beatriz , Paiva Felipe Marina Gabriely , Souza Taveira Raíssa , Souza Ribeiro Tatiana , Fernandes Bezerra Clarissa
Published: November 2023

A Doença de Parkinson (DP) é uma doença neurodegenerativa, progressiva e que repercute negativamente em diversos aspectos, entre eles a marcha, funcionalidade e qualidade de vida. Uma das modalidades de reabilitação é o tratamento fisioterapêutico em grupo, o qual possibilita a troca de experiências entre pacientes, maior adesão na intervenção, interação social e melhora da autoestima. O objetivo deste estudo é relatar a experiência de discentes do projeto de extensão AGruPar (Assistência fisioterapêutica em Grupo para indivíduos com DP) da Universidade Federal do Rio Grande do Norte (UFRN). O projeto visa oferecer um tratamento fisioterapêutico associado à interação social entre indivíduos com a mesma doença, e proporciona aos discentes um melhor manejo da DP e da prática clínica em grupo em ambiente presencial e remoto.
O PAPEL DO NUPLAM-UFRN NO ENFRENTAMENTO DA COVID-19 NO ESTADO DO RIO GRANDE DO NORTE
Authors: Mafra Verissimo Lourena , Ferreira Leite Ingrid
Published: November 2023

Com o surgimento de um novo coronavírus (SARS-CoV-2) severamente infectante em humanos, a Organização Mundial da Saúde (OMS) decretou pandemia devido aos níveis alarmantes de propagação em março de 2020. Frente a uma crise sanitária e o aumento da demanda de produtos antissépticos como um dos principais combativos ao vírus, o mercado sofreu dificuldades em suprir toda população na aquisição destes produtos. Neste sentido, a Universidade Federal do Rio Grande do Norte (UFRN), somou esforços para o combate à pandemia, sendo uma de suas ações, a produção de álcool 70% INPM, pelo Núcleo de Pesquisa em Alimentos e Medicamentos (NUPLAM), sua unidade suplementar. Esta pesquisa é apresentada como um relato de caso, de caráter descritivo e retrospectivo, acerca desta atividade. Foi feito um levantamento de dados referente ao processo de produção e distribuição de solução de álcool 70% INPM realizado no NUPLAM-UFRN, para o estado do Rio Grande do Norte (RN), com um recorte de tempo entre 02 de abril à 07 de agosto do ano de 2020. A produção total ultrapassou os 70 mil litros de álcool, que foram distribuídos a todo o estado, incluindo hospitais universitários, secretarias de saúde do estado do RN e município de Natal, e setores de saúde e ensino incluídos na própria UFRN. No ano de 2021, a curva do número de casos confirmados no RN continua em crescimento assim como a demanda pelos cuidados com a higienização, sendo imprescindível a continuidade das ações em combate à pandemia.
Trabalho e a sociobiodiversidade a partir de experiências etnofotográficas na feira do Juaba, Cametá/PA
Authors: Saboia Tiago Corrêa
Published: November 2023

A partir da compreensão da fotografia e da imagem enquanto forma de linguagem, busco desenvolver neste ensaio uma narrativa imagética acerca da experiência na Feira livre do distrito de Juaba, localizado no município de Cametá/PA. Nesse sentido, a partir do trabalho e a sociobiodiversidade, marcas indissociáveis do habitar o território, busco destacar as vivências e experiências sentidas/percebidas com as pessoas e com o lugar.
Rural e urbano em trânsito
Authors: Silva Antonio Micael Pontes da , Lima Antonio Ailton de Sousa , Oliveira André Victor da Silva
Published: November 2023

Este estudo se constitui em torno das questões que permeiam o ato fotográfico e as formas de expressão visual do social no âmbito da mobilidade rural e urbana. Objetiva-se analisar a fotografia como dispositivo e instrumento teórico-metodológico de compreensão social entre rural e urbano tendo como fio condutor o pau de arara. Assim, versa sobre uma experiência fotográfica na comunidade rural Riacho das Pedras até o centro urbano de Redenção, no Ceará. O artigo segue uma abordagem qualitativa, ancorada na observação participante sob uma análise crítica do discurso. Este percurso permite estimular um olhar crítico e simultaneamente imagético das dinâmicas cotidianas entre rural e urbano que fomenta a realidade social de uma cidade interiorana.
Estabilidad transversal de buques pesqueros con trimado libre
Authors: Valerio Mena Lenin J.C. , Rodríguez Castillo Claudio A.
Published: November 2023

Gran parte de los accidentes con embarcaciones pesqueras se deben a problemas de estabilidad transversal durante la faena de pesca, en la cual la embarcación se escora grandes ángulos, y muchas veces al no lograr recuperarse, zozobra. En los estudios y peritajes llevados a cabo por las Aseguradoras generalmente se llega a la conclusión de que la embarcación superó su límite de estabilidad. Este límite de estabilidad en algunos casos puede no haberse evaluado correctamente. En este trabajo se discute la eficiencia del cálculo de estabilidad estática transversal usado en el diseño de buques y embarcaciones pesqueras de la flota peruana, basados en los diagramas de curvas cruzadas de estabilidad tradicional que condiciona el trimado de la embarcación a permanecer inalterado. Los calculos realizados por el método tradicional son comparados con otros realizados utilizando un método de cálculo de trimado libre, basado en el concepto del equilibrio hidrostático de cuerpos flotantes. 
Se presenta el método de cálculo con trimado libre incluyendo un caso ilustrativo.
Estudio químico de la Liana Ayahuasca (Banisteriopis caapi)
Authors: Reyna pinedo Víctor , Torpoco Carmen Virginia , Sánchez Ramirez Tania
Published: November 2023

De la liana Ayahuasca (Banisteriopsis caapi) se aisló la harmina, que fue identificada mediante su punto de fusión y el análisis porcentual de elementos. Asi mismo, se registraron sus espectros de masas, de RMN'H y RMN"C, IR y UV. Además, se realizó el análisis cuantitativo de los metabolitos secundarios y la cuantificación del total de alcaloides presentes en la planta [1].
Software basado en procesamiento digital de una base de datos topográficos, para el cálculo de los niveles RSSI en BTS de telefonía celular
Authors: Díaz Zegarra José Alberto , Kemper Vásquez Guillermo , Muñoz Meza José Luis
Published: November 2023

Se implementó un software en ambiente visual, que realiza el análisis de cobertura de una BTS de telefonía celular, a partir de parámetros proporcionados por el fabricante de la antena y de los datos digitales correspondientes a la topografía del lugar. El software implementado tiene interfaces graficas para ingresar los parámetros de la antena, patrón de radiación, etc, y coordenadas de la ubicación. El programa presenta un informe visual de la cobertura mediante un código de colores, indicando los diferentes niveles de recepción y el informe sobre los datos obtenidos del cálculo de cobertura de una estación base, usando modelos matemáticos para sistemas outdoor. Los datos para la validación del presente trabajo fueron obtenidos de la implementación de una estación base celular de pruebas, consistente en un transmisor de telefonía celular en la banda de 800 MHz, antena sectorial, se realizó la medición de los niveles recibidos RSSI y estos son comparados con los teóricos y luego son graficados en Matlab para determinar el error absoluto entre los valores reales y los obtenidos mediante el software.
Ship route simulation based on the cluster analysis
Authors: Akmaykin D. A. , Bocharova V. V. , Klyueva S. F.
Published: November 2023

The problem of safe ship’s route planning at the variable hydrometeorological situation along the route is considered in the paper. The problem solved in the paper is based on the division of the water area into separate clusters, depending on its characteristics. The route from Busan Port to Kushiro Port is used as an example. The specifics of this route is that it runs through the open sea, and through the straits and archipelagos. The aim of the work is to automate the process of planning the route and adjusting it during the trip, depending on changes in external conditions. The graph theory for modeling a route is proposed in this paper. The construction of graphs is implemented using the cluster analysis method. In the analysis, the water area of the route is divided into separate subareas, depending on the distance to the coast and the depths difference. Open water areas are separated into larger clusters. Near the coast and at shallow depths, clustering is shorter. The cluster centroids are the vertices of the graphs of the future route. As result it is a simulation of graphs of different sizes. The union of graphs forms the hypergraph. The distance is used as the weight of the graph edges. To determine the most preferable route in criteria of speed, cost or safety, weights are added depending on weather and other factors. As a result of this approach, several routes are planning on the hypergraph. Depending on the weight of the priority criteria, a route is selected automatically. The proposed method can be used to create systems for automated planning of optimal routes, taking into account the selected criteria under changing environmental conditions in the process of voyage and replanning it if necessary.
Determination of the optimal period for computations control in complexes of automated control systems programs
Authors: Goloskokov K. P. , Korotkov V. V. , Astapkovich A. A.
Published: November 2023

The purpose of the study is to determine the optimal period for monitoring calculations in complex software complexes of automated control systems. To achieve this goal, it is necessary to solve such problems as the analysis of periodic control systems, which boils down to determining the performance costs of computing systems for control, as well as ensuring a minimum of these costs. Theoretical foundations and descriptions of the process of evaluating the effectiveness of the automated control systems functioning are given. A rationale for the method of determining the optimal period for monitoring calculations in software complexes of the automated control systems is provided in the paper. An analytical study of control systems is carried out. The difference between the considered problem setting and the existing ones lies in the fact that the accuracy of error detection by the periodic control system is taken into account, while it is taken into account that for real control systems the probability of error detection is quite high. Thus, the results of studying the operational periodic control systems have shown that the main parameters that affect the optimal period of control are the mean time between failures. The dependence of the optimal control period on the probability of recovery is shown for different values of the duration of recovery by a reliable method. As the probability decreases, the optimal control period also decreases, which is associated with the need to spend a large proportion of the time on restoration using a reliable method; the corresponding increase in average unit costs can be compensated by an increase in the frequency of control procedures, i. e. a decrease in the control period. The dependence of the minimum average unit cost of control and the optimal period of its implementation on the average time between the errors appearance is given. With constant durations of control and recovery procedures and constant error detection probability, the optimal control period decreases, and the minimum average unit cost increases somewhat with a decrease in the average time between failures. This can be explained as follows: the more often an error can occur, the more often you need to control in order to reduce the losses due to working with the error.
La Evaluación de los Aprendizajes en Inglés como Lengua Extranjera desde una Perspectiva Fenomenológica
Authors: Sergio-Luis Ayazo Santos  , Robin-Samuel Flórez Salgado  , Daniel-Enrique Carranza Torres
Published: November 2023

Sergio-Luis Ayazo Santos; Robin-Samuel Flórez Salgado; Daniel-Enrique Carranza Torres
German Version of the Mobile Agnew Relationship Measure: Translation and Validation Study (Preprint)
Authors: von Wulffen Clemens , Marciniak Marta Anna , Rohde Judith , Kalisch Raffael , Binder Harald , Tuescher Oliver , Kleim Birgit
Published: November 2023

BACKGROUND

The mobile Agnew Relationship Measure (mARM) is a self-report questionnaire for the evaluation of digital mental health interventions and their interactions with users. With the global increase in digital mental health intervention research, translated measures are required to conduct research with local populations.

OBJECTIVE

The aim of this study was to translate and validate the original English version of the mARM into a German version (mARM-G).

METHODS

A total of 2 native German speakers who spoke English as their second language conducted forward translation of the original items. This version was then back translated by 2 native German speakers with a fluent knowledge of English. An independent bilingual reviewer then compared these drafts and created a final German version. The mARM-G was validated by 15 experts in the field of mobile app development and 15 nonexperts for content validity and face validity; 144 participants were recruited to conduct reliability testing as well as confirmatory factor analysis.

RESULTS

The content validity index of the mARM-G was 0.90 (expert ratings) and 0.79 (nonexperts). The face validity index was 0.89 (experts) and 0.86 (nonexperts). Internal consistency for the entire scale was Cronbach α=.91. Confirmatory factor analysis results were as follows: the chi-square statistic to df ratio was 1.66. Comparative Fit Index was 0.87 and the Tucker-Lewis Index was 0.86. The root mean square error of approximation was 0.07.

CONCLUSIONS

The mARM-G is a valid and reliable tool that can be used for future studies in German-speaking countries.
Mobile App for Gynecologic Cancer Support for Patients With Gynecologic Cancer Receiving Chemotherapy in China: Multicenter Randomized Controlled Trial (Preprint)
Authors: Lin Huicong , Ye Mingzhu , Lin Yanjuan , Chen Fuhong , Chan Sally , Cai Hongxia , Zhu Jiemin
Published: November 2023

BACKGROUND

Patients with gynecologic cancer receiving chemotherapy often report unmet supportive care needs. Compared with traditional face-to-face clinical interventions, mobile health can increase access to supportive care and may address patients’ needs. Although app-based support programs have been developed to support patients with gynecologic cancer, their efficacy has not been adequately tested.

OBJECTIVE

The aim of this study was to examine the efficacy of a mobile app for gynecologic cancer support (MGCS) for patients with gynecologic cancer receiving chemotherapy in China.

METHODS

A multicenter randomized controlled trial was conducted in 2 university-affiliated hospitals in China. A total of 168 Chinese patients with gynecologic cancer were recruited and randomized to receive routine care or MGCS program plus routine care for 24 weeks. The Mishel uncertainty in illness theory guided the development of MGCS program, which has 4 modules: weekly topics, emotional care, discussion center, and health consultation. The primary outcome of this program was the assessment of the uncertainty in illness. The secondary outcomes were quality of life, symptom distress, and social support. All health outcomes were evaluated at baseline (T0), 12 weeks (T1), and 24 weeks (T2). Repeated measures analysis of covariance was used to assess the efficacy of the MGCS program.

RESULTS

In this trial, 67 patients in the control group and 69 patients in the intervention group completed 2 follow-up assessments (response rate, 136/168, 81%). At 12 weeks, no significant differences were observed in any of the health outcomes between the 2 groups. At 24 weeks, compared to patients in the control group, those in the intervention group reported significant decreased uncertainty in illness (P<.001; d=–0.60; adjusted mean difference –7.69, 95% CI –11.31 to –4.07) and improved quality of life (P=.04; d=0.30; adjusted mean difference 4.77, 95% CI 0.12-9.41).

CONCLUSIONS

The MGCS program demonstrated efficacy in supporting patients with gynecologic cancer receiving chemotherapy. This trial illustrates that an app-based program can be incorporated into routine care to support patients with cancer and suggests that allocation of more resources (grants, manpower, etc) to mobile health in clinics is warranted.

CLINICALTRIAL

Chinese Clinical Trial Registry ChiCTR2000033678; https://www.chictr.org.cn/showproj.html?proj=54807
The WebRA study: Implementation perspectives of using a digital patient education programme in clinical practice (Preprint)
Authors: Raunsbæk Knudsen Line , Lomborg Kirsten , Hauge Ellen-Margrethe , de Thurah Annette
Published: November 2023

BACKGROUND

The integration of telehealth interventions into clinical practice is frequently delayed, hindering the full adoption. Previously, we developed a digital patient education programme for self-management in rheumatoid arthritis (RA). While the programme design considered crucial factors to ensure the likelihood of success in clinical practice, there is a need for a thorough and systematic evaluation of implementation perspectives.

OBJECTIVE

To explore perspectives of implementation in using a digital patient education programme in clinical practice.

METHODS

The non-adoption, abandonment, scale-up, spread and sustainability (NASSS) framework was used to evaluate the successes and challenges of implementing the digital patient education programme. We included a data set consisting of qualitative focus group discussions involving study nurses, rheumatologists, and leaders from rheumatology departments. Data analysis was guided by a deductive content analysis approach. Further we included data from earlier studies pertaining to the programme's implementation, comprising the programme development process, a randomized controlled trial evaluating the programme's effectiveness, and a qualitative study exploring patients' perspectives of the programme.

RESULTS

Facilitators and challenges of importance to implementation of digital PE were identified. While a wide range of patients could benefit from using digital PE, future implementation should aim for an even broader group than those studied. Both patients and healthcare providers embraced the technology, and the fact that it did not require specific technical skills enhances its potential for success. However, offering digital PE should be based on individual assessments, and expanding its use will require organizational adjustments. An adaptable structure is needed to accommodate unforeseen care needs that may arise following the use of digital PE at home. There was indication of some reluctance among healthcare providers toward the programme shown by concerns about changing roles, which could impact the adoption of the program.

CONCLUSIONS

The design and ease of use of the technology, the program's effectiveness, its availability, and the potential to release healthcare resources may encourage the implementation of digital patient education. Challenges associated with implementing this mode of care pertains to the illness and the patient population, user adoption of the technology, and the organization of patient education.

CLINICALTRIAL

N/A
Sobre llovido, mojado. Pandemia y violencias en poblaciones vulnerables en el Área Reconquista (Provincia de Buenos Aires)
Authors: Caravaca Evangelina , Garriaga Zucal José , Mancini Inés
Published: November 2023

La pandemia del COVID-19 produjo enormes transformaciones a lo largo de todo el mundo; las mismas son aún difíciles de describir y comprender. En la Argentina, el impacto de la crisis económica, social y sanitaria agudizó las desigualdades. En esta investigación nos propusimos estudiar si más allá del agravamiento de las desigualdades que produjo la pandemia, se habían modificado los mapas de las violencias en la Argentina. Para ello, trabajamos sobre los criterios de legitimidad de ciertas violencias y las intensidades durante la pandemia.

Con este objetivo, analizaremos las diferentes formas de violencias en un área geográfica vulnerable en el partido de General San Martín (Buenos Aires, Argentina), específicamente el Área Reconquista. Nos interesa dar cuenta, al tiempo que problematizar, la geografía de las violencias en su relación con la vulnerabilidad y en especial el accionar de las fuerzas de seguridad en estas dinámicas sociales. Los datos cualitativos y cuantitativos que se retoman en este artículo son el producto de una investigación realizada entre febrero y agosto del 2021 que buscó reflexionar sobre mutaciones y continuidades de las manifestaciones violentas en estos espacios como resultado de la emergencia sanitaria producida por el COVID-19. Entre otras tareas de investigación, se realizaron sesenta entrevistas en profundidad a vecinos, fuerzas de seguridad y funcionarios del área Reconquista del partido de General San Martín (provincia de Buenos Aires).
Nudo gordiano: habitares y violencia. Puebla, México
Authors: Cabrera Becerra Virginia , Morales Cabrera Axel Alfredo , López Vargas Lilia Varinia , Olvera Nava Mónica Erika
Published: November 2023

La relación habitares de violencia atrapa la desgarrante realidad de nuestra sociedad actual. La constitución de lugares, hábitats, territorios, ha estado atravesada por violencias múltiples y exclusiones diversas a lo largo del proceso civilizatorio. En las condiciones actuales del modelo neoliberal, la búsqueda de ganancia anudada a valores instrumentales como la competitividad y la individualidad continúa de manera férrea con la configuración, desfiguración y reconfiguración de los territorios, los habitares, de la mayoría de la población, en particular de las poblaciones rurales e indígenas. El objetivo que se persigue es reflexionar acerca de la simbiosis existente entre los habitares y la violencia en nuestras sociedades actuales. Para desplegar análisis concretos, un primer peldaño es realizar un ejercicio de reflexión acerca de los conceptos involucrados: habitares y violencia, para avanzar en el desentrañamiento, a través de un proceso reflexivo y comparativo, con los hechos concretos, que asume la violencia en México y en Puebla en diversas espacialidades y variadas dimensiones de la violencia. El énfasis se realizará en la pobreza, el espacio público y la violencia de género.
Florestan Fernandes y el “capitalismo dependiente”
Authors: Del Roio Marcos
Published: November 2023

Este artículo presenta la contribución del sociólogo brasileño Florestan Fernandes en el ámbito de la teoría de la dependencia, producida durante su exilio en América del Norte. Se basa en tres ensayos presentados en encuentros científicos en el campo de la Sociología que abordan el tema general del “capitalismo dependiente”, con diferentes enfoques y que fueron publicados en Brasil, en 1973, en formato de libro con el título Capitalismo dependente e classes sociais na America Latina. El primero trata de los patrones de dominación externa ejercidos sobre América Latina; el segundo intenta presentar la naturaleza del “capitalismo dependiente” y su relación con la constitución de clases sociales; el tercero habla de la inserción del sociólogo en el contexto del “capitalismo dependiente”. El artículo expone las ideas de Florestan Fernandes, intercalando algunas observaciones sobre la metodología utilizada y las implicaciones de las conclusiones ofrecidas. Al final, se presenta una síntesis de las críticas realizadas a la elaboración del sociólogo brasileño, cuyo fulcro es precisamente el límite analítico del funcionalismo estructural retocado con las categorías de Max Weber, concepción teórico-metodológica que envuelve la reflexión sobre la acción política orientada a la revolución socialista, valientemente defendida por el autor.
Indian Cervical Cancers: Understanding of Epidemiological Profile through the National Cancer Registry Programs Findings
Authors: Gaikwad Sujata P.
Published: November 2023

Abstract: According to a recent analysis from the Lancet research, India has the highest rate of cervical cancer malignancies in all of Asia. The study claims that India alone is responsible for 23% of cervical cancer-related deaths in Asia. According to the GLOBOCAN report 2020, India has a high mortality rate of 62.42%, which is higher than that of both Asia and the rest of the globe. Due to the severe lack of resources, cervical cancer is a big issue in India. Based on an analysis of data from a significant cancer registry network, this study investigates the epidemiological characteristics of cervical cancer in India in great detail. In accordance with the PBCR 2020 (ICMR-NCDIR; 2020), the truncated rate (TR) in the districts of Aizawl, Dibrugarh, and Kollam was six times, five times, and four times larger, respectively, than the TR rate in the districts of Papumpare, Mizoram, and Pasighat. In the entire country, we discovered considerable regional and socioeconomic variations in the incidence of cervical cancer, with a clear gradient of increased incidence in areas with lower levels of human development. Combining HIV testing and cervical cancer screening during a single appointment with a primary care provider would be a cost-effective option.
An analysis of science communication about COVID-19 vaccination in Portuguese online news media
Authors: Santana Elaine , Bernardo Joana , Donici Inga , Valente Rúben , Pedro Bárbara , Almeida Inês , Silva Sílvia , Alegre Conceição , Loureiro Teresa , Silva Rosa
Published: November 2023

This study aimed to analyze the usage of scientific concepts and technical terms related to COVID-19 vaccination in Portuguese online news sources and examine citizens' comprehension of these terms. A retrospective descriptive study was conducted, examining Portuguese news articles about COVID-19 vaccination from November 2021 to January 2022. Scientific terms were extracted from 190 articles, and seven citizens provided identification and brief definitions of familiar terms. Approximately 68% of the news articles involved collaboration with researchers or health professionals. A total of 144 scientific terms were identified in 77% of the articles, with more than half (57.54%) of these terms being unknown or inadequately defined by the citizens consulted.
Una propuesta de valores para su consideración en el patrimonio arquitectónico
Authors: BENCHENNI Fatima , MEBROUKI Abdelkader , MONJO-CARRIÓ Juan
Published: November 2023

Los valores del patrimonio arquitectónico deben ser un criterio básico para su análisis antes de cualquier acción de intervención y mantenimiento. Para su correcta definición nos basamos en un análisis crítico de las propuestas existentes desde principios del siglo XIX. En este trabajo analizamos los valores y subvalores incluidos en las cartas de restauración históricas y actuales, los que se pueden deducir de las leyes de conservación en algunos países, y los que han propuesto los autores más reconocidos en este campo a lo largo de los últimos tiempos. Con ello elaboramos una propuesta de valores que ayudarán a definir los criterios adecuados para la intervención en el patrimonio arquitectónico.
The contribution of bank intermediation to economic growth: Empirical evidence from CESEE countries
Authors: Miftari Florije
Published: November 2023

The financial system is the crucial supporter of economic growth, as it is said to be the “blood” of economic activities. Many studies reveal the role and importance of the financial system in promoting economic development by raising growth through the accumulation and utilization of savings for productive investments (Levine, 2005). However, some studies highlight a negative or non-significant relationship which may differ depending on the sample of countries and the applied methodology, proxy of financial development, time period, etc. Based on the relevance of the topic and on the ongoing debate, the aim of this study is to explore the nexus and contribution of banking intermediation in the economic growth of some Central Eastern and South-Eastern European (CESEE) countries for the period 2010–2020. We use regression methods, ordinary least squares (OLS), and a fixed effect model to investigate the relationship between economic growth and bank intermediation. We measure the development of banking intermediation using banks’ credit to the private sector, credit to government and state-owned enterprises. The research results show that credits provided by banks do not affect economic growth and are in fact negatively related to economic growth, whereas the return on equity is positively related to economic growth.
Glycoside flavonoids of genus Morus: Phytochemistry, Biosynthesis and Pharmacological activities
Authors: Fatima Maryam , Bukhari Mohd Nadeem , Bukhari Jehangir Shah Syed , Dar Mudasir A. , Ouyang Zhen
Published: November 2023

Traditional natural products have been the focus of research to explore
their medicinal properties. One such medicinally important plant is
Morus alba, which is growing very quickly, especially in Asia, and has
tremendous pharmacological activities due to the presence of
phytochemicals in various parts of this plant. In this review, we
provide a comprehensive summary of the phytochemistry, biosynthetic
pathways, and pharmacological activities of glycoside flavonoids in the
leaves of Morus alba has been studied. In the past centuries, mulberry
has been considered a food source for silkworms, and its leaves are used
to feed animals for livestock. However, in recent years, mulberry has
attained a special place in research because of its phytochemical
composition and benefits to human health, including antioxidant,
anticancer, antidiabetic, and immunomodulatory effects. Phytochemicals
are bioactive compounds present in plants that work with nutrients and
dietary fiber to protect against diseases. Morus alba also contains many
phytochemicals, such as flavonoids, phenols, and anthocyanins. The
biosynthetic pathway is greener and more efficient for producing
structurally diverse natural products. This pathway acts as an
alternative to chemical synthesis and microbial transformation, which
suffer from complex routes, difficult isomer separation, and high cost.
The mechanism of the flavonoid biosynthesis pathway in mulberry leaves
is not yet clear, and currently, this is a much-needed topic for
scientists to explore.
Triple-Therapy for Prurigo Nodularis: A Case Report
Authors: Carver Caden , Shah Syed Hakeem , Ahmed Najia
Published: November 2023

Prurigo nodularis (PN) is a chronic condition of unknown etiology that
presents with pruritic, excoriated dome-shaped lesions on the
extremities. It is challenging to treat using topical therapies alone.
Newer options include monoclonal antibodies, as well as excimer UVB and
psoralen UVA phototherapies. While these have shown clinical efficacy,
they may
Viable morphology control strategy enabled by EG solvothermal treatment for high capacitance PEDOT:PSS films
Authors: Zhang Wanying , Su Zhen , Nie Shisong , Jin Yingzhi , Song Jiaxing , Hu Lin , Yin Xinxing , Wang Wentao , Ning Weihua , Yang Xiaoming , Wang Hao , Li Zaifang
Published: November 2023

Thick and highly conductive PEDOT:PSS films with ideal morphologies, are
desirable as electrodes for supercapacitors. However, building uniform
micro-morphology without templates or composite strategies is a
formidable challenge, primarily caused by the inherent softness of
dominant PSS. Herein, we successfully realized morphology control,
transitioning from a layer-by-layer architecture to a porous structure
in thick PEDOT:PSS films by employing solvothermal method with ethylene
glycol (EG) as the solvent. The combined effect of high pressure and
temperature effectively drove EG to construct the microstructure of
thick PEDOT:PSS films by detaching insulating PSS chains and enhancing
PEDOT crystallinity, and simultaneously facilitated the formation of a
porous network through EG molecular tailoring. The achieved porous thick
PEDOT:PSS films delivered a high conductivity of 1644 S cm-1 and a
champion specific capacitance of 270 F cm-3, significantly surpassing
previously reports. The flexible all-solid-state supercapacitor
assembled based on the films displayed an excellent specific capacitance
of 97.8 F cm-3 and an energy density of 8.7 mWh cm-3, representing the
highest values for pure PEDOT:PSS-based supercapacitors. This research
provides an effective novel method for conducting polymer morphology
control and promotes the applications of PEDOT:PSS in the field of
energy storage.