bluuebunny/crossref_metadata_2025 huggingface dataset:
INTERACTIVE MEDIA DEVELOPMENT FOR SECOND GRADE ELEMENTARY STUDENTS THEMATIC LEARNING USING ADOBE FLASH CS4 PROFESSIONAL
Authors: Nugraha R. Gita Ardhy
Published: June 2017

Interactive media can be used to support the thematic learning process. From the observation on second grade Satya Wacana Christian Elementary School, it was found that second grade’s teacher did not use interactive media to support thematic learning. Students were lack of interest to learn. Because of this problem, an interactive media is developed as a new way to support the thematic learning process. The aim of this study is to describe the appropriateness of interactive media based on Adobe Flash CS4 Professional and the effect of interactive media implementation in the 2013th Curriculum thematic learning process. The method in this study is research and development. The result showed that interactive media was proper to use as learning media in the thematic learning process based on expert test score (3,83 & 3,23). Interactive media has a very good value based on field test score (4,24 & 4,26). Using interactive media affected student’s interest and motivation. The media also given attractiveness and effectiveness in the thematic learning process based on the questionnaire by students and second grade’s teachers. 
Analysis of Petroleum Downstream Industry Potential in Riau Province
Authors: Erfando Tomi , Herawati Ira
Published: June 2017

Petroleum downstream industry in Riau Province is still not optimal. The data shows that from 98,892,755 barrels lifting oil each year only 62,050,000 barrels could be processed in refinery unit II Dumai operated by PT Pertamina. There is a potential of 35-40% of downstream industry. Indonesian Government through The Ministry of Energy and Mineral Resources declared the construction of a mini refinery to boost oil processing output in the downstream sector. A feasibility study of development plan mini refinery is needed. The study includes production capacity analysis, product analysis, development & operational refinery  analysis and economic analysis. The results obtained by the mini refinery capacity is planned to process crude oil 6000 BOPD with the products produced are gasoline, kerosene, diesel and oil. Investment cost consist of is capital cost US $ 104419784 and operating cost US $ 13766734 each year with net profit earned US $ 12330063/year and rate of return from investment 11.63%
Urban Green Space Development Strategy–Reconverting Gas Station To Public Parks In The City Of Surabaya, Indonesia
Authors: Hasyimi Valid , Suroso Djoko Santoso Abi
Published: June 2017

Urban Green Space Development has become a challenging task for city governments especially in Indonesia, due to high prices of land around urban centers. On the other hand, there are inconsistencies between land use and land allocation within the city planning. In Surabaya City, quite a lot of gas stations were built on areas which are originally intended for green open spaces. Surabaya City Municipality is strongly committed to reconvert Gas Station Areas to green open spaces as determined in the plan. Innovative strategies have enabled the city government to reconvert 13 gas stations to public parks. This paper analyzes the implementation process of the Urban Green Space Reconversion Policy, describing the historical details of the issues, the  taking over of land from gas station owners, and the park development and campaigning. Discussion also includes the most influential factors in this success story.
ANALISIS PERMUKIMAN PEMULUNG SEBAGAI SEBUAH ASSEMBLAGE STUDI KASUS: PERMUKIMAN PEMULUNG DI WILAYAH JURANGMANGU, TANGERANG SELATAN
Authors: Permanasari Eka
Published: June 2017

ABSTRAK. Keberadaan pemulung adalah suatu fenomena umum di kota-kota Indonesia.  Dalam fenomena keberadaan pemulung, terdapat sebuah paradoks.  Di satu sisi, terdapat pandangan bahwa pemulung memiliki pengaruh negatif bagi lingkungan sosial maupun fisik.  Di sisi lain, pekerjaan sebagai pemulung memberi kontribusi positif dalam hal proses daur ulang sampah serta dalam memberikan alternatif lapangan kerja.  Paradoks ini membuat keberadaan pemulung menarik untuk dikaji, baik dari segi sosial, ekonomi, maupun lingkung bangunnya. Kajian mengenai pemulung dari sudut pandang sosial dan ekonomi telah banyak dilakukan dalam berbagai penelitian.  Namun, sejauh ini, belum ada penelitian yang membahas persoalan pemulung dari sudut pandang lingkung bangun permukimannya.  Penelitian ini dilakukan untuk memberi kontribusi dalam hal tersebut. Penelitian ini bertujuan untuk memperoleh gambaran mengenai pembentukan dan perubahan lingkung bangun permukiman pemulung, berdasarkan hasil observasi terhadap dua permukiman pemulung di Jurangmangu, Tangerang Selatan, dan wawancara kepada penghuninya.  Bentukan suatu lingkung bangun terkait dengan pola kegiatan, serta dipengaruhi oleh faktor-faktor sosial dan ekonomi dari manusia di dalamnya.  Untuk itu, penelitian ini membahas tentang lingkung bangun permukiman pemulung serta hubungannya dengan pola aktivitas dan sistem sosial ekonomi penghuninya. Kata kunci: permukiman pemulung, assemblage. ABSTRACT. The phenomena of informal waste-picker settlements are very common in many cities in developing countries. Behind the rapid development and the image of economical wealth, lies beneath the informal waste-picker settlements which may often be overlooked. The existence of the informal waste-picker settlements is like two sides of a knife. On one hand, the settlements are often perceived as giving the negative impact to the social and physical condition of the city. On the other hand, their job in reducing waste and providing alternative employment is perceived as giving positive impact to the city. This binary oppositions and their impact to the social, economical condition and  the built environment  are the focus of this research  There are some research on social and economical condition of informal waste-picker settlements. However, the research on the urban assemblage of informal waste-picker settlements are not very common. Therefore, this research focus on how the social and economical condition shape the informal waste-picker settlements in terms of urban assemblage.  This research investigates the development and transformation of the informal waste-picker settlements in two prime locations in Jurangmangu, South Tangerang. The methods are through observation and interview to key persons (leaders) on each settlement. The urban assemblage on these waste-picker settlements is heavily influenced by social and economical condition and activity of their users.  Key words: waste picker settlements, urban assemblage, informality
AUTOMATICTECTURE : OTOMATISASI PENUH DALAM ARSITEKTUR MASA DEPAN
Authors: Gunagama M Galieh , Lathifa Nur Fitri
Published: June 2017

ABSTRAK. Teknologi memudahkan umat manusia dalam hidup, akan tetapi, perkembangan yang terjadi juga membawa dampak negatif berupa terancamnya sejumlah profesi dengan adanya otomatisasi. Proses otomatisasi telah menggantikan porsi pekerjaan manusia dengan mesin berkecerdasan, dan tren tersebut akan semakin membesar seiring berjalannya waktu. Dalam hubungannya dengan studi eksperimental dan prediksi masa depan, dunia rancang bangun juga memiliki kemungkinan untuk diotomatisasikan dengan adanya perkembangan dalam bidang arsitektur digital, robotika, dan kecerdasan buatan. Di tengah kondisi global yang serba cepat dan penuh dinamika, dunia arsitektur perlu mempersiapkan diri dalam menghadapi perkembangan tersebut jika tidak ingin segera digantikan. Diskusi dalam paper ini mencoba untuk mengeksplorasi lebih dalam dan memprediksikan profesi arsitek pada masa depan dalam skenario terbaik dan terburuk terkait perkembangan proses otomatisasi yang semakin tidak terhindarkan. Kata kunci: Arsitektur Eksperimental, Arsitektur Digital, Teknologi, Masa DepanABSTRACT. Technology facilitates mankind in life, however, developments that occurred also had a negative impact in the form of threats to a number of professions with automatization. Automation process has replaced the portion of human work with the intelligent machine, and the trend will be growing over time. In conjunction with experimental studies and future predictions, the design and construction field also have the possibility to be automated with the development in the field of digital architecture, robotics, and artificial intelligence. Amid the global fast-paced and dynamic environment, architecture needs to be prepared in facing such developments if do not want to immediately replaced. The discussion in this paper attempts to explore deeper and predict the future of the profession in the best and worst case scenario related to the development of automation process which is increasingly unavoidable.Keyword: Experimental Architecture, Digital Architecture, Technology, Future
STUDI EMPIRIS PENERAPAN MANAJEMEN NILAI PADA PENGEMBANGAN REAL ESTATE DI SURABAYA
Authors: Sari Yeptadian
Published: June 2017

ABSTRAK. Penerapan sebuah metode dalam pengembangan real estat sangat dibutuhkan agar memastikan proyek berjalan dengan lancar. Terdapat metode yang mampu meningkatkan nilai proyek dan bahkan membuang biaya yang tidak perlu dalam proyek yang disebut dengan metode manajemen nilai atau value management (VM). Metode ini masih jarang digunakan di Indonesia namun sebagian besar pengembang real estat di Surabaya mengaplikasikannya. Penelitian ini mencari tahu tentang studi empiris dari penerapan VM pada pengembangan real estat di Surabaya, lebih spesifiknya yaitu mencari tahu tentang bagaimana VM digunakan di perusahaan pengembang real estat di Surabaya. Penelitian ini merupakan penelitian eksploratif  dengan metode penelitian analisa statistik deskriptif. Metode penentuan sampel dengan non-probabiliti sampling gabungan, yaitu dengan purposive sampling yang dilanjutkan dengan snowball sampling. Sedangkan teknik pengumpulan datanya menggunakan survei dengan alat kuesioner. Hasil dari penelitian ini diketahui bahwa 80% perusahaan pengembang real estat di Surabaya tidak memiliki pelaksana desain dan pelaksana proyek sendiri, dan mereka tidak dilibatkan dalam tujuan proyek sejak tahap preliminary, mereka baru dilibatkan sejak tahap desain konseptual. Selain itu, penelitian ini menemukan fakta bahwa 60% petinggi perusahaan pengembang real estat mengasumsikan bahwa manajemen nilai (VM) adalah rekayasa nilai (VE). Kata kunci : real estate, manajemen nilai, studi empiris. ABSTRACT. The application of a method in real estate development process is needed in order to ensure the project runs smoothly. There are methods that can indrease the value of the project and even discard the unnecessary cost of the project called value management. Many practitioners of real estate development in Surabaya claim that they always apply value management method. However, based on empirical data, it is known that not much research of value management in Surabaya. Thepurpose of this paper is to determine the empirical study of VM by the practitioners of real estate development in Surabaya. This is an exploratory research with statistic descriptive analysis that is used to achieve the research objectives. The sample taking and respondent determination are applied by a purposive sampling followed by snowball sampling. Data collection techniques use a survey by distributing the questionnaires.  Outcome of the analysis indicate that 80% of real estate development companies in Surabaya do not have executive design and project implementers. Design implementers and project officers are not involved in achieving the objectives of the project, these professionals began to be involved in the conceptual stages of design. Beside, this research finds that 60% of practitioners assume that VM is VE. Keywords : real estate, value management, empirical study.
A new emerging problem in pediatric emergency units: Synthetic cannabinoids
Authors: Aladağ-Çiftdemir Nükhet , Yücel İlay , Duran Rıdvan , Vatansever-Özbek Ülfet , Acunaş Betül
Published: June 2017

Synthetic cannabinoids or synthetic marijuana derivatives known as "Bonzai" in Turkey are addictive substances that affect the brain and have serious side effects. In recent years, the use of these substances has also been increasing in our country as well as all over the world. These substances present with various names and brands, the most common names in Turkey are "Bonzai" and "Jamaika". In this study, we aimed to evaluate the demographic and clinical findings of these patients. We retrospectively evaluated patients admitted to our pediatric emergency department between March 2013 and March 2015 due to the complaints developing after the use of "Bonzai" in terms of age, gender, admission date, complaint, clinical findings, laboratory findings, consuming method of the substance, additional substance use, observation durations, hospitalization status and mortality rates. The most common complaint was faintness and drowsiness. Changes in the state of consciousness, tachycardia, hypertension were the most common clinical findings. Most common consuming method of the drug was in the form of smoking. The rate of "Bonzai" use among adolescents is increasing every day. Physicians in emergency departments should be educated on this issue and it must be kept in mind that most of the patients admitted are with complaints related to changes in the cognitive state (of consciousness) but they can also apply with complaints about all other systems.
Waist to height ratio: a simple screening tool for nonalcoholic fatty liver disease in obese children
Authors: Özhan Bayram , Ersoy Betül , Özkol Mine , Kiremitci Seniha , Ergin Ahmet
Published: June 2017

Simple predictors are needed for the screening of nonalcoholic fatty liver disease (NAFLD) in obese children. We aimed to assess the role of anthropometric parameters in the prediction of NAFLD. Three hundred and thirty two obese children (152 male, 180 female) aged 4.6-17.0 years were included in this study. Weight, height, waist (WC), and hip circumference were measured. Body mass index (BMI), waist-hip-ratio (WHR), and waist-height-ratio (WHtR) were calculated. Obesity was defined as BMI for age and sex ≥ 95th percentile. NAFLD was diagnosed using ultrasonography (US). NAFLD was present in 60.8% of obese children. Fatty liver prevalence differed significantly by gender and puberty (55.0% of girls vs 67.7% of boys, and 28.7% in prepubertal vs 71.3% in pubertal children; p < 0.05). Significantly higher BMI, BMI standard deviation score (SDS), WC, and WHtR were found in obese children with NAFLD compared to obese children without NAFLD (p < 0.05). Only WHtR was found to be an independent predictor for NAFLD in a logistic regression analysis (p < 0.001, B:1.096, 95% CI 1.047-1.148). Fatty liver is common among obese children, particularly in obese boys. WHtR is a simple and easy index for predicting of NAFLD in obese children and can be used for mass screening in public health.
Detection of gastroesophageal reflux in children with cerebral palsy using combined multichannel intraluminal impedance-ph procedure
Authors: Çaltepe Gönül , Yüce Özlem , Comba Atakan , Özyürek Hamit , Kalaycı Ayhan Gazi , Taşdemir Haydar Ali
Published: June 2017

Gastroesophageal reflux (GER) is a very common condition in children with neurological impairment and this can influence nutritional and respiratory outcomes. The aim of this study was to investigate the presence of GER in children with cerebral palsy (CP) using multiple intraluminal impedance (MII)-pH monitoring. The use of combined MII-pH allows for the detection of both acid and non-acid reflux episodes. A total of 29 CP patients with symptoms suggesting GER, aged 2 to 10 years old, underwent 24-hour combined MII-pH monitoring. There were a total of 3899 reflux episodes, of which 29% were acid, 60% were weakly acid and 11% were alkaline. The number of non-acid reflux episodes was statistically significantly greater (p < 0.01). These findings confirm that GER disease is seen frequently in children with cerebral palsy and most of the reflux episodes are not acidic. Non-acid reflux can also influence the morbidity in patients with cerebral palsy. It can be concluded that 70% of the reflux episodes would not have been recognized by pH measurement alone.
Primary intrarenal neuroblastoma in a 13-month-old girl presenting as a Wilms' tumor with pulmonary metastasis
Authors: Telli Onur , Ateş Ufuk , Ergun Ergun , Yıldız Rahşan Vargun , Yağmurlu Banu , Yalçın Bilgehan , Bilezikçi Banu , Göllü Gülnur , Yağmurlu Aydın
Published: June 2017

We report a 13-month-old girl with primary intrarenal neuroblastoma initially diagnosed as Wilms' tumor. Intrarenal neuroblastoma is exceedingly rare in pediatric age that may masquerade as Wilms' tumor clinically and radiographically and it is important to differentiate for management.
Bone marrow aspiration complications: Iliopsoas abscess and sacroiliac osteomyelitis
Authors: Tural-Kara Tuğçe , Özdemir Halil , Fitöz Suat , Çiftçi Ergin , Yalçınkaya Fatoş
Published: June 2017

After bone marrow aspiration procedure; some complications like pain and bleeding at the puncture site may be expected but some serious complications like osteomyelitis and soft tissue infections may also rarely occur. In this case we present a boy with recurrent fever. During etiologic investigation, familial Mediterranean fever (FMF) gene M694V mutation was +/+. Patient was treated with oral colchicine however fever persisted. The patient was considered as colchicine resistant FMF and steroid treatment was planned. Bone marrow aspiration procedure was executed to rule out malignancy. Three months after bone marrow aspiration, he was readmitted with complaint of left pelvic pain, difficulty in walking without support and standing on his left foot. Radiological imaging demonstrated left iliopsoas abscess and left sacroiliac osteomyelitis. Patient was successfully treated with intravenous ampicillin-sulbactam and clindamycin treatment for 6 weeks. Then oral amoxicillin-clavulanic acid treatment was continued for 2 weeks. Patient was discharged without any surgical procedure. On 1-year follow-up he could walk without any support.
Rosai-Dorfman disease of vertebra: Case report and literature review
Authors: Igrutinovic Zoran , Medovic Rasa , Markovic Slavica , Kostic Gordana , Raskovic Zorica , Tanaskovic-Nestorovic Jelena , Radovanovic Marija , Vuletic Biljana
Published: June 2017

Rosai-Dorfman disease is a rare benign histiocytic disorder that arises predominantly in lymph nodes with fever and malaise, but can affect various organs, with or without lymphadenopathy. Solitary extranodal skeletal lesions are extremely rare. Herein, we describe a case of isolated disease of thoracic spine, with vertebral body fracture. A 14-year-old girl presented with cervical back pain for about one month as the only symptom. There was no lymphadenopathy. Results of laboratory tests were within reference ranges. The radiological examinations revealed collapse, osteolytic lesion and compressive fracture, which reduced vertical diameter of C4 vertebral body. The patient made a complete recovery after a limited C4 laminectomy, spondylodesis C3/C5 vertebra and biopsy of the lesion. Histologically, nonspecific cellular milieu and atypical histiocytic proliferation with emperipolesis, with CD68 and S100 positivity, confirmed a diagnosis of Rosai-Dorfman disease. Isolated extranodal skeletal Rosai-Dorfman disease should be considered among the differential diagnoses of similar changes, such as Langerhans cell histiocytosis, Erdheim-Cheister disease, eosinophilic granuloma, osteomyelitis, metastasis and lymphoma.
Characterization of some food formulation functional properties of flour processed from roasted African breadfruit (Treculia africana) seeds
Authors: Umezuruike Azubuike Chris , Nwabueze Titus U.
Published: June 2017

This study used Response Surface Methodology was used to roast, identify and characterize the optimum values of functional properties of African breadfruit (Treculia africana) seed flour processed for industrial applications. The central Composition Rotable Design of treatment variables at 3 process variables (Roasting temperature RT, Roasting Time RM, and feed quantity FQ) and 5 process levels (-1.682, -1, 0, 1, 1.682) was used to optimize bulk density water and oil absorption capacities, gelation and emulsion capacity of the produced flour. Functional properties of the flour increased above the value of control and relative to process treatment. The effect of roasting temperature was significant (p < 0.05) for bulk density, gelation and emulsion capacity. Roasting time and feed quantity significantly (p˂0.05) influenced water absorption and emulsion capacities of the flour. Optimum values were bulk density 0/79 g/cm3, water absorption capacity 4.00ml/g, oil absorption capacities 2.90m/g, gelation 8.92 w/v. The unified optimum values of the functional properties occurred at process treatment combination of 126.360C, 45.85min and 505.09g, respectively for temperature, time and quantity. Processing African breadfruit seeds into flour at the optimal point will enhance its usefulness in industrial applications were functional properties of flour are of processing important.
Association between Vitamin D Receptor Gene Polymorphism and Susceptibility to Tuberculosis (TB): a Meta Analysis
Authors: Dong Yuanyuan , Gu Yu , Guan Mengxiang , Li Haibo , Zou Yunfei , Song Jiangen , Ding Lei , Wen Yufeng
Published: June 2017

Objective: The study was carried out to comprehensively evaluate association between Vitamin D receptor gene polymorphism and susceptibility to TB, using meta-analysis.

Methods: Literature on controlled case studies on association between vitamin D receptor gene polymorphism and TB were collected through online database (Pubmed, Chinese CNKI, VIP database, Wanfang database and Google search). Odd ratio (OR) of all the studies were collected depending on the result of their heterogeneity tests. Publication bias was assessed by using a funnel plot and Egger’s test.

Results: Eight papers were selected based on study criteria. Meta analysis results showed that the combined OR values (95%CI) of dominant model and recessive model were 0.51(0.40,0.65) and0.72(0.61, 0.85), They were both statistically significant (P<0.001). Significant associations were observed for Fok? polymorphisms among Chinese.

Conclusion: The results suggest that Vitamin D receptor gene polymorphism was significantly associated with TB in China. Our findings support the hypothesis that vitamin D deficiency might play a role in TB infection and development of associated risk factors.
Effect of Probiotics Supplementation on Blood Glucose: a Meta-analysis of Randomized Controlled Trials
Authors: Li Haibo , Zhang Qian , Chen Yujuan , Zou Yunfei , Zhu Yu , Li Jie , Wen Yufeng
Published: June 2017

Purpose: Thisstudy was carried out as a meta-analysis to assess whether probiotics supplementation can reduce blood glucose (BG) levels in Type 2 diabetes mellitus (T2DM) patients.

Methods: The analysis included 1005 subjects from 15 probiotics supplementation randomized trials in which changes in BG were reported as one of the end points. Summary estimates of weighted mean differences (WMDs) and 95% confidence intervals (CIs) were obtained by using random-effect models. Meta-regression and sub-group analyses were performed to identify sources of heterogeneity.

Results: Probiotics supplementation was associated with significant decreases in BG levels (WMD: -0.29 mmol/L; 95% CI: -0.56, -0.02; P = 0.038), particularly in subjects with T2DM (WMD: -1.11 mmol/L; 95% CI: -1.54, -0.68; P< 0.001), and in trials carried out in Iran (-0.74 mmol/L; 95% CI: -1.30, -0.18; P = 0.009). Baseline BG levels were positively related to magnitude of effect (P< 0.001). Greater bene?cial effects were consistently seen in trials with baseline BG levels ? 7.0 mmol/L (WMD: -0.881 mmol/L; 95% CI: -1.357, -0.405; P < 0.001). However, in the corresponding comparison groups, magnitudes of effect were attenuated and non-signi?cant.

Conclusion: These results indicate that probiotics supplementation is effective in reducing the BG levels in subjects with T2DM and in trials with higher baseline BG levels.
The serum level of Cystatin c in different gender and its influence factors
Authors: Zou Yunfei , Ding Lei , Chen Yujuan , Chen Baifeng , Wen Yufeng
Published: June 2017

Objective: To investigate the serum level of Cystatin c and its influence factors.

Methods: A cross-sectional study was performed among 322 population who came to physical examination center of one hospital and had a physical examination during march 2012 to august 2012, a questionnaire survey was carried out and some biochemical criterions were detected. The formula of modification of diet in renal disease (MORD) was used to estimate glomerular filtration rate (eGFR).

Results: The average serum level of Cystatin c was 1.05±0.13 mg/L,and the level in male was higher than that in female and the difference had statistical significance(t=4.353, P=0.000). Multiple stepwise linear regression analysis showed that the increase of age, uric acid, urea nitrogen and weekly meat intake and the decrease of estimated glomerular filtration rate related with a higher serum level of Cystatin c in male, and the increase of age, uric acid, urea nitrogen, systolic blood pressure and monthly bean products intake and the decrease of estimated glomerular filtration rate related with a higher serum level of Cystatin c in female.

Conclusions: The serum level of Cystatin c is different in different gender. The increase of age and the serum level of uric acid, urea nitrogen, and the decrease of estimated glomerular filtration rate related with a higher level of Cystatin c both in male and female, however, it still

exists some differences that the weekly meat intake only increase the serum level of Cystatin c in male and the monthly bean products intake only increase the serum level of Cystatin c in female.
Induced Abortion among Chinese Women with Living Child-A National Study
Authors: Sun Wenjie , Donovan Connor , Xu Tan , Zheng Yumei
Published: June 2017

ABSTRACT

Objective: Induced abortion is widely practiced in China. However, the information on induced abortion is limited. A national cross-sectional survey was designed to determine the risk factors of induced abortion among Chinese women with one child.

Methods: We sampled 16,881 Chinese women with one living child for the study. A structured questionnaire was used to collect induced abortion and related health information. The National Research Institute for Family Planning of China conducted a cross-sectional study among women who had delivered a baby between 2006 and 2008. Information was collected in relation to demographic characteristics (age, ethnicity, region, area etc.), social economic status (education level and occupation), marriage, and the attitude towards potential child’s gender. Multi-logistic regression was used to test potential predictors for conducting abortion stratified by consistency between gender preference and current infants’ gender, and indicating adjusted estimation on selected models of risk factors for abortion.

Results: The mean age of participants was 27.96 ± 4.10 years (median 27 years).  Among those women, the prevalence of induced abortion was 8.13 %. In the final model, females living in rural areas (OR = 1.21, 95 %CI: 1.04-1.39), individuals ages 18-25 (OR = 0.84, 95% CI: 0.72-0.99), individuals ages 30 or older (OR = 1.63, 95% CI: 1.42-1.86), and single individuals (OR = 1.72, 95% CI: 1.05-2.83) were more likely to experience induced abortion. Wife gender preference (OR = 0.66, 95 %CI: 0.53-0.83), husband gender preference (Boy: OR = 1.33, 95 %CI: 1.10-1.63; Girl: OR = 1.5, 95% CI: 1.22-1.86), and the area where the individuals were located were significantly associated with the reporting of induced abortion.

Conclusion: The prevalence of induced abortion is high among married women with child in China. There are also socio-demographic characteristics associated with induced abortion in China.
Human T-lymphotropic viruses (HTLV) in England and Wales, 2004 to 2013: testing and diagnoses
Authors: Ireland Georgina , Croxford Sara , Tosswill Jennifer , Raghu Rajani , Davison Katy , Hewitt Patricia , Simmons Ruth , Taylor Graham
Published: June 2017

Human T-lymphotropic virus (HTLV) infection has been under enhanced surveillance in England and Wales since 2002, however, little is known about testing patterns. Using data from two surveillance systems held at Public Health England, we described HTLV antibody testing patterns between 2008 and 2013 and the demographic and clinical characteristics of persons diagnosed with HTLV in England and Wales between 2004 and 2013. An increase in HTLV testing was observed in England between 2008 and 2013 (3,581 to 7,130). Most tests (82%; 7,597/9,302) occurred within secondary care, 0.5% (48/9,302) of persons were reactive for HTLV antibodies and 0.3% (27/9,302) were confirmed positive. Increasing age and female sex were predictors of a reactive HTLV screen and confirmed diagnosis. Testing in primary care including sexual health and antenatal services was infrequent. Between 2004 and 2013, 858 people were diagnosed with HTLV, most of whom were female (65%; 549/851), of black Caribbean ethnicity (60%), not born in the United Kingdom (72%; 369/514) and asymptomatic at diagnosis (45%; 267/595). Despite increased testing, the epidemiology and clinical features of those diagnosed with HTLV have remained consistent. Apart from donor screening, testing for HTLV infection remains uncommon, except to diagnose associated disease.
Development and validation of the HCV-MOSAIC risk score to assist testing for acute hepatitis C virus (HCV) infection in HIV-infected men who have sex with men (MSM)
Authors: Newsum Astrid M , Stolte Ineke G , van der Meer Jan TM , Schinkel Janke , van der Valk Marc , Vanhommerig Joost W , Buvé Anne , Danta Mark , Hogewoning Arjan , Prins Maria ,   on behalf of the MOSAIC (MSM Observational Study of Acute Infection with hepatitis C) study group
Published: June 2017

Current guidelines recommend hepatitis C virus (HCV) testing for HIV-infected men who have sex with men (MSM) with ongoing risk behaviour, without specifying the type of risk behaviour. We developed and validated the HCV-MOSAIC risk score to assist HCV testing in HIV-infected MSM. The risk score consisted of six self-reported risk factors identified using multivariable logistic regression using data from the Dutch MOSAIC study (n = 213, 2009–2013). Area under the ROC curve (AUC), sensitivity, specificity, post-test-probability-of-disease and diagnostic gain were calculated. The risk score was validated in case–control studies from Belgium (n = 142, 2010–2013) and the United Kingdom (n = 190, 2003–2005) and in cross-sectional surveys at a Dutch sexually transmitted infections clinic (n = 284, 2007–2009). The AUC was 0.82; sensitivity 78.0% and specificity 78.6%. In the validation studies sensitivity ranged from 73.1% to 100% and specificity from 56.2% to 65.6%. The post-test-probability-of-disease ranged from 5.9% to 20.0% given acute HCV prevalence of 1.7% to 6.4%, yielding a diagnostic gain of 4.2% to 13.6%. The HCV-MOSAIC risk score can successfully identify HIV-infected MSM at risk for acute HCV infection. It could be a promising tool to improve HCV testing strategies in various settings.
How Research–Policy Partnerships Can Benefit Government: A Win–Win for Evidence-Based Policy-Making
Authors: Richards Garrett Ward
Published: June 2017

What is the appeal of evidence-based policy-making to policy-makers themselves? What is the appeal of being influenced to make decisions they would not otherwise make? In this article, I argue that forging partnerships between research organizations and policy agencies can result in seven short-term benefits for the latter, independent of decision influence. These potential benefits are a more intuitive initial basis for partnership, and genuine influences on policy-making may still emerge over the long term. Overall, this article serves as a general argument in favour of evidence-informed policy, and research–policy partnerships in particular, directed at both academic and government audiences.
Licht aus - Spot an: How Schlager (ZDF 1969-1984) Beat Disco (ZDF 1971-1982)
Authors: Simon Sunka
Published: June 2017

During the broadcast era, dominant culture reigned supreme on
West German television. Das Zweite Deutsche Fernsehen (ZDF) achieved ratings
of close to 74 percent during the long Saturday slot in the 1970s. This mass
reach, especially of its live popular music programs with built-in audience
votes, is often disregarded in historical arguments that focus on the political disunion
of that decade. This article takes a closer look at two very different, yet
exceptionally popular music shows, Deutsche Hitparade (1969–1984) and Disco
(1971–1982), to investigate how the anxiety over sociopolitical change is negotiated
on live television, how medium specificity intersects with constructions of
masculinity and authority, and how different music and television formats
question, manage and produce a national imaginary.
Wenn eine Band lange Zeit lebt: Puhdys, Politics, and Popularity
Authors: Littlejohn John
Published: June 2017

This article examines the rise of the East German rock band the
Puhdys, focusing primarily on the songs collected in their eponymous first
album. Such an examination provides a long overdue reappraisal of the
Puhdys’ early years, establishing not only that they benefitted from fortuitous
timing, but also that their early music and lyrics conveyed sophisticated multivalent
messages that helped them reach a youthful rock audience without
running afoul of the authorities. This article also reveals the degree to which
East German radio and the West German record industry fostered the rise of
“DDRock” and later cemented its place in the East German cultural arena.
Evaluation of ischemic lesion prevalence after endovascular treatment of intracranial aneurysms, as documented by 3-T diffusion-weighted imaging: a 2-year, single-center cohort study
Authors: Iosif Christina , Lecomte Jean-Christophe , Pedrolo-Silveira Eduardo , Mendes George , Boncoeur Martel Marie-Paule , Saleme Suzana , Mounayer Charbel
Published: June 2017

OBJECTIVE

Even though published data exist concerning the prevalence of ischemic lesions detected by diffusion-weighted imaging (DWI) following endovascular treatment of intracranial aneurysms, a single-center cross-evaluation of the different endovascular techniques has been lacking. The authors sought to prospectively evaluate the prevalence and clinical significance of ischemic lesions occurring after endovascular treatment of intracranial aneurysms and to compare the safety and effectiveness of a broad spectrum of currently accepted endovascular techniques in a single-center setting.

METHODS

This was a prospective cohort study involving consecutive patients treated for intracranial aneurysms exclusively by endovascular means, excluding treatments in the acute rupture phase, in a center featuring an endovascular-only treatment policy for intracranial aneurysms. All patients underwent MRI, including a 3-directional DWI sequence, before treatment, 24 hours postprocedure, and 6 months following endovascular embolization. Selective angiography was performed at 6 months’ follow-up.

RESULTS

From January 2012 through December 2013, 164 aneurysms were treated in 128 consecutive patients. Endovascular techniques included coiling (14.6%), balloon-assisted coiling (20.1%), stent-assisted coiling (3.7%), low-profile stent-assisted coiling, flow diversion (38.4%), and very complex treatments (6.1%) involving 2 stents in Y or T configurations. On postprocedure MRI, the rates of occurrence of new DWI-positive lesions were 64.3% for coiling, 54.5% for remodeling, 61.1% for stent-assisted coiling, 53.7% for flow-diverting stents, and 75% for very complex treatments (p = 0.4962). The 6-month procedure-related morbidity and mortality rates were 6.25% and 0%, respectively. At 6 months’ follow-up, 93% of the patients had modified Rankin Scale (mRS) scores of 0–2. Very complex treatments offered a higher complete occlusion rate (100%) than all other techniques (66.7%–88.9%). Age and length of procedure were independent factors for DWI lesion occurrence. The diameter of DWI lesions on 24-hour postprocedure MRI was positively correlated with mRS score at discharge. Among the DWI-positive lesions measuring less than 2 mm in diameter on the 24-hour MRI, 44.12% had regressed at 6 months.

CONCLUSIONS

Procedure-related DWI lesions are far more often encountered in silent forms than they are clinically evident. They do not seem to be significantly correlated with procedure-related complications, nor do they seem to impair clinical outcome, regardless of the endovascular technique. Small lesions (< 2 mm in diameter) may regress within 6 months. The use of the most adapted technique, in terms of aneurysm configuration, results in significant total occlusion rates, with acceptable safety.
Surgical strategy to avoid ischemic complications of the pyramidal tract in resective epilepsy surgery of the insula: technical case report
Authors: Ikegaya Naoki , Takahashi Akio , Kaido Takanobu , Kaneko Yuu , Iwasaki Masaki , Kawahara Nobutaka , Otsuki Taisuke
Published: June 2017

Surgical treatment of the insula is notorious for its high probability of motor complications, particularly when resecting the superoposterior part. Ischemic damage to the pyramidal tract in the corona radiata has been regarded as the cause of these complications, resulting from occlusion of the perforating arteries to the pyramidal tract through the insular cortex. The authors describe a strategy in which a small piece of gray matter is spared at the bottom of the periinsular sulcus, where the perforating arteries pass en route to the pyramidal tract, in order to avoid these complications. This method was successfully applied in 3 patients harboring focal cortical dysplasia in the posterior insula and frontoparietal operculum surrounding the periinsular sulcus. None of the patients developed permanent postoperative motor deficits, and seizure control was achieved in all 3 cases. The method described in this paper can be adopted for functional preservation of the pyramidal tract in the corona radiata when resecting epileptogenic pathologies involving insular and opercular regions.
Robot-assisted endoscopic third ventriculostomy: institutional experience in 9 patients
Authors: Hoshide Reid , Calayag Mark , Meltzer Hal , Levy Michael L. , Gonda David
Published: June 2017

OBJECTIVE

The endoscopic third ventriculostomy (ETV) is an established and effective treatment for obstructive hydrocephalus. In its most common application, surgeons plan their entry point and the endoscope trajectory for the procedure based on anatomical landmarks, then control the endoscope freehand. Recent studies report an incidence of neural injuries as high as 16.6% of all ETVs performed in North America. The authors have introduced the ROSA system to their ETV procedure to stereotactically optimize endoscope trajectories, to reduce risk of traction on neural structures by the endoscope, and to provide a stable mechanical holder of the endoscope. Here, they present their series in which the ROSA system was used for ETVs.

METHODS

At the authors’ institution, they performed ETVs with the ROSA system in 9 consecutive patients within an 8-month period. Patients had to have a favorable expected response to ETV (ETV Success Score ≥ 70) with no additional endoscopic procedures (e.g., choroid plexus cauterization, septum pellucidum fenestration). The modality of image registration (CT, MRI, surface mapping, or bone fiducials) was dependent on the case.

RESULTS

Nine pediatric patients with an age range of 1.5 to 16 years, 4 girls and 5 boys, with ETV Success Scores ranging from 70 to 90, underwent successful ETV surgery with the ROSA system within an 8-month period. Their intracranial pathologies included tectal tumors (n = 3), communicating hydrocephalus from hemorrhage or meningeal disease (n = 2), congenital aqueductal stenosis (n = 1), compressive porencephalic cyst (n = 1), Chiari I malformation (n = 1), and pineal region mass (n = 1). Robotic assistance was limited to the ventricular access in the first 2 procedures, but was used for the entirety of the procedure for the following 7 cases. Four of these cases were combined with another procedural objective (3 stereotactic tectal mass biopsies, 1 Chiari decompression). A learning curve was observed with each subsequent surgery as registration and surgical times became shorter and more efficient. All patients had complete resolution of their preprocedural symptoms. There were no complications.

CONCLUSIONS

The ROSA system provides a stable, precise, and minimally invasive approach to ETVs.
Use of Adjuvant Chemotherapy in Patients with Advanced Bladder Cancer after Neoadjuvant Chemotherapy
Authors: Sui Wilson , Lim Emerson A. , Joel Decastro G. , McKiernan James M. , Anderson Christopher B.
Published: June 2017

Objectives:

To compare the outcomes of adjuvant chemotherapy (AC) versus observation in patients with non-organ confined disease after neoadjuvant chemotherapy and radical cystectomy (RC).

Materials and methods:

Using the National Cancer Database, we identified patients who received NAC prior to RC and had advanced stage (pT3/4) or pathologically involved nodes (pN+) at the time of surgery from 2004–2013. We determined whether patients then received AC or were managed with observation only and used multivariable proportional hazards regression to estimate the impact of AC on overall survival.

Results:

Overall 34% (N = 705) of patients who received NAC and underwent RC were pT3/4 and/or pN+. Of these patients, 24% (N = 168) received subsequent chemotherapy and the rest were observed. Median survival for the entire cohort was 21 months (IQR 12–45). There was not a statistically significant difference in median survival between the AC and observation groups (23 months [IQR 14–46] versus 20 months [IQR 12–46], log-rank p = 0.52). On multivariate analysis there was no survival advantage for the AC cohort. Subgroup analysis of pN+ patients who received AC also did not show a survival advantage.

Conclusions:

Patients who are pT3/4 and/or pN+ after NAC and RC have a poor prognosis. The addition of AC does not seem to be beneficial. Further research should focus identifying patients who may benefit from additional chemotherapy.
What Drives Positive Youth Development? Assessing Intentional Self-Regulation as a Central Adolescent Asset
Authors: Gestsdottir Steinunn , Geldhof G. John , Lerner Jacqueline V. , Lerner Richard M.
Published: June 2017

The “5 Cs of PYD Model” is an influential theory involving the role of Intentional Self-Regulation (ISR) in positive youth development (PYD). The model, which was developed with U.S. populations, has recently been used in other cultural contexts and, as such, the measurement invariance of the ISR-PYD model across cultural contexts must be assessed. This study examined whether the ISR-PYD model is conceptually similar across two cultures, the U.S. and Iceland. Participants were 2,473 U.S. and 539 Icelandic adolescents (65% female, 15.00 years; 46% female, 14.30 years, respectively). Results suggested weak invariance and partial strong invariance for PYD and partial weak invariance across groups and time for ISR. Bifactor modeling showed that ISR was more strongly associated with global PYD than individual Cs. These findings demonstrate construct validity of the ISR-PYD model, suggesting that ISR is a central asset in general healthy functioning among youth in different Western cultural contexts.
Recovery from Proactive Semantic Interference and MRI Volume: A Replication and Extension Study
Authors: Loewenstein David A. , Curiel Rosie E. , DeKosky Steven , Rosselli Monica , Bauer Russell , Grieg-Custo Maria , Penate Ailyn , Li Chunfei , Lizagarra Gabriel , Golde Todd , Adjouadi Malek , Duara Ranjan
Published: June 2017

Background: The rise in incidence of Alzheimer’s disease (AD) has led to efforts to advance early detection of the disease during its preclinical stages. To achieve this, the field needs to develop more sensitive cognitive tests that relate to biological markers of disease pathology. Failure to recover from proactive interference (frPSI) is one such cognitive marker that is associated with volumetric reductions in the hippocampus, precuneus, and other AD-prone regions, and to amyloid load in the brain.

Objective: The current study attempted to replicate and extend our previous findings that frPSI is a sensitive marker of early AD, and related to a unique pattern of volumetric loss in AD prone areas.

Methods: Three different memory measures were examined relative to volumetric loss and cortical thickness among 45 participants with amnestic mild cognitive impairment.

Results: frPSI was uniquely associated with reduced volumes in the hippocampus ( r = 0.50) precuneus ( r = 0.41), and other AD prone regions, replicating previous findings. Strong associations between frPSI and lower entorhinal cortex volumes and cortical thickness (r≥0.60) and precuneus ( r = 0.50) were also observed.

Conclusion: Unique and strong associations between volumetric reductions and frPSI as observed by Loewenstein and colleagues were replicated. Together with cortical thickness findings, these results indicate that frPSI is worthy of further study as a sensitive and early cognitive marker of AD.
A machine learning approach to analyze ODI cricket predictors
Authors: Jayalath Kalanka P.
Published: June 2017

As one-day international (ODI) games rise in popularity, it is important to understand the possible predictors that affect the game outcome. The home-field advantage, coin-toss result, bat-first or second, and day vs day-night game format are such popular variables being considered in the cricket literature. This article focuses on a comprehensive study of quantifying the significance of those important predictors via graphical ‘classification and regression tree’ (CART) and the popular logistic regression approaches. This study reveals the importance of the home-field advantage for major cricket playing nations in one-day international games but questions the uniformity of such factors under different playing conditions. Importantly, the home-field advantage is investigated further based on the opponent’s geographical location. Conclusively, the CART approach provides interesting and novel interpretations for popular predictors in ODI games.