bluuebunny/crossref_metadata_2025 huggingface dataset:
Straddle-Type Monorail State Assessment Based on Adaptive Whale Optimization Algorithm
Authors: Liu Zhanghao , Liao Jingbo , Meng Libo , Chen Yixin , Gong Qinghua , Kong Yunsen , Luo Cong
Published: September 2023

The condition parameter evaluation of straddle-type monorail beam based on finite element model modification is a high-dimensional parameter optimization problem, which tends to fall into local optimization. The whale optimization algorithm has the advantages of few required parameters, and good optimization search, while it has rarely been applied in the bridge engineering field, and its applicability needs further verification. Therefore, an analytical framework based on the adaptive whale optimization algorithm and deflection influence line is constructed using finite element model modification techniques, and its feasibility is verified for high-dimensional parametric state assessment of straddle-type monorails. The results show that the adaptive whale optimization algorithm can be used in the condition assessment of straddle-type with a maximum error of 3.5% in the identification of high-dimensional (20-dimensional) parameters, and the accuracy and rate of the algorithm are optimized for the standard whale optimization algorithm; in addition, using the deflection influence line of 1/4 span, mid-span and 3/4 span as the optimization target can reduce the error and improve the accuracy of the condition assessment of rail beams.
An alternative foundation of quantum theory
Authors: Helland Inge Svein
Published: September 2023

A new approach to quantum theory is proposed in this paper. The basis is first taken to be theoretical variables, variables that may be accessible or inaccessible, i.e., it may be possible or impossible for an actor to assign arbitrarily sharp numerical values to them. In an epistemic process, the accessible variables are just ideal observations connected to an actor or to some communicating actors. Group actions are defined on these variables, and group representation theory is the basis for developing the Hilbert space formalism here. Operators corresponding to accessible theoretical variables are derived, and in the discrete case, it is proved that the possible physical values are the eigenvalues of these operators. The focus of the paper is some mathematical theorems paving the ground for the proposed foundation of quantum theory. It is shown here that the groups and transformations needed in this approach can be constructed explicitly in the case where the accessible variables are finite-dimensional. This simplifies the theory considerably: To reproduce the Hilbert space formulation, it is enough to assume the existence of two complementary variables. To focus only on physical variables rather than mathematical variables, the concept of inaccessible variables is then replaced by the concept of notions, and in this connection, aspects of category theory partly replace group theory. The interpretation inferred from the proposed foundation here may be called a general epistemic interpretation of quantum theory. A special case of this interpretation is QBism; it also has a relationship to several other interpretations.
Експериментальне дослідження сформованості каузального мислення здобувачів загальної середньої освіти
Authors: Жук Юрій , Ващенко Лідія , Науменко Світлана
Published: September 2023

Авторами запропоновано й апробовано методику оцінювання рівня сформованості каузального мислення, засновану на тестових технологіях. Методика полягає у використанні критеріально-орієнтованого тесту, що містить дві групи запитань, формулювання яких ініціює різну розумову діяльність учнів. В одній групі запитань запропоновані для вибору варіанти можливих причинно-наслідкових зв’язків між процесами, явищами чи подіями, що вивчаються в даній предметній галузі (каузально-орієнтована група запитань). Інша група запитань спрямована на знання раніше вивчених понять і явно не містить прохання вказати причинно-наслідкові зв’язки між ними (не каузально-орієнтована група запитань). Обидві групи запитань представлені тестовими завданням із вибором відповіді із низки запропонованих варіантів.З метою дослідження властивостей тесту в його структурі використовувалися опції «складність» та «вагаюся». Отримані в результаті експерименту дані дозволяють зробити висновок, що запропонована структура тесту показала достатню здатність диференціювати результати педагогічних вимірювань щодо каузально-орієнтованих та не каузально-орієнтованих запитань, що, своєю чергою, дає можливість порівняти в учнів рівні засвоєння навчального матеріалу та сформованості каузального мислення під час використання одного тесту. Короткий формат тесту уможливлює його використання безпосередньо під час реального освітнього процесу. Складання тестових завдань доволі просто реалізувати вчителеві самостійно відповідно до цілей контролю контекстного навчання.
Protective Factors of Preventing Proximal Junctional Kyphosis as the Most Common Complication of Adult Spinal Deformity Surgery
Authors:   Assistant Professor and Chief of Neurosurgery Department , Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran, Nabiuni Mohsen , Hatam Jaber ,   Assistant Professor of Neurosurgery Department , Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran, Haghbin Susan ,   Researcher in Neurosurgery Department , Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
Published: September 2023

Background and Aim: This study aims to provide information about the common complications of adult spinal deformity (ASD) surgery that requires revision surgery and proximal junctional kyphosis (PJK) as the most common complication. We emphasized crucial protective factors that reduce the risk of post-operative PJK, especially the careful selection of the upper instrumented vertebra (UIV) and gradual transitional zone on the proximal end of the construct. Methods and Materials/Patients: This study is a retrospective review of the adult population with spinal deformity who underwent posterior instrumentation surgery and requires revision surgery due to post-operative complications, such as disc herniation, screw loosening, rod breakage, distal junctional failure, and symptomatic PJK. Fifteen ASD patients requiring revision surgery were included. We evaluated the ratio of age, gender, the prevalence of postoperative complications, and the most common complication of PJK based on Cobb angle and patient symptoms. Results: This study included 15 patients with ASD who underwent posterior spinal instrumentation surgery and experienced post-operative complications requiring revision surgery. As a result, 6 patients out of 15 (40%) had PJK, four patients (26.6%) had disc herniation and canal stenosis, two patients (13.3%) had screw loosening, one patient (6.6%) had rod breakage and two patients (13.3%) had distal junctional failure required revision surgery. Conclusion: In our study, PJK is at the top of the complications and two risk factors have a great impact on predisposing ASD surgery to the post-operative PJK, that is, the UIV level, and gradual transitional zone at the proximal end of the construct, therefore the risk of this unfortunate outcome can be significantly minimized by carefully selecting UIV and hooks using a smooth gradual transitional zone along with other protective factors.
THE CONCEPT OF "LEAN PRODUCTION" IN THE SYSTEM OF STRATEGIC MANAGEMENT OF TRANSPORT ENTERPRISES
Authors:   State University of Infrastructure and Technology, Shkurenko Olga
Published: September 2023

The article is devoted to the study of problems and obstacles that may arise when implementing the concept of "Lean Production" (thrifty production) at enterprises of the transport industry in the system of strategic management. A number of possible problems and obstacles that arise when implementing the concept of "Lean Production" (thrifty production) into the management system of transport enterprises are outlined. The factors of successful implementation of the concept of "Lean Production" (thrifty production) in the system of strategic management of transport enterprises, through which the enterprise will be able to counteract possible barriers, are summarized in the section of groups. It is emphasized that the concept of "Lean Production" is implemented through systems of lean production or their components, in particular, technologies of analysis, improvement and involvement, which allows to optimize costs and resources in the system of strategic management of transport enterprises, as well as to create maximum value for the client. The transition from a traditional production system to a lean production is not an easy task. Change requires attention focused on impacting both process and people. Despite the widespread coverage of the benefits obtained from the implementation of the concept of "Lean Production" (thrifty production), there are a number of reasons for the failure of the application of this approach to the strategic management of transport enterprises. Lack of understanding of the concept and purpose of lean production is the main obstacle on the way to the implementation of the concept of "Lean Production". Misunderstanding the concept leads to various major problems, such as fragmentary or partial implementation of lean production tools and methods or their complete incorrect application. In order to successfully implement the concept of "Lean Production" in the strategic management system of transport enterprises, management must take innovations seriously, set goals for continuous improvement, and be interested in the experience of similar domestic and foreign enterprises. Taking into account the proposed list of factors for the successful implementation of the concept of "Lean Production" (thrifty production) in the system of strategic management of transport enterprises will ensure the efficiency of business processes, saving costs, improving the level of customer service and strengthening relations with them
Observational study of the effects of an osteopathic treatment for patients with fibromyalgia
Authors: Laroche F. , Bellan E. , Doléac M. , Meslé R. , Marty M. , Rostaing S.
Published: September 2023

Background. The aim of this study is to evaluate the effects of an osteopathic treatment on the main symptoms of Fibromyalgia: pain, quality of sleep, anxiety, depression, deterioration in the quality of life. Methods. This open, prospective and observational pilot study included 13 patients, all of them submitted to an osteopathic treatment. The study took place in the «Centre d′Évluation et de Traitement de la Douleur» (Centre of Evaluation and Treatment of Pain) at the «Saint-Antoine» Hospital in Paris. The osteopathic treatment has been adapted to each patient without pre-established procedure of treatment. Six sessions with three weeks intervals (± seven days). The intensity as well as the impression of alteration of the symptoms has been evaluated before the first and after the last session of treatment with the following auto evaluation forms: QCD, QIF, PSQI, HAD and PGIC. Results. In all 13 patients (women: 92%, middle-aged 51 years), the Quality of Life (QIF) improved with 34% namely from 73,9±10,2 to 48,7±17,6 (p<0.0001). The Sleep score (PSQI) decreased with 25 % i. e. 13,3±3,3 to 10±3,4 (p=0003) as well as Pain that decreased with 38 %, that is from 58,5±15,7 to 36,2±16,1 (p=0,005). Anxiety decreases with 25 %, namely from 10,5±4,2 to 7,9±4,5 (p=0,004).There was no significative diminishing of Depression. Conclusion. The results of this cohort are encouraging even if the high standard deviations seem to be the mirror of important interindividual differences. A controlled, randomized trial with more patients is necessary to confirm these data.
Investigating Improvement in Gadolinium Detection for a XRF Bone Measurement System by Averaging Spectrum
Authors: Crawford Daniel
Published: September 2023

An X-ray fluorescence (XRF) measurement system involving a high purity germanium detector (HPGe) was used to quantify gadolinium and lanthanum in bone. The 24-hour ex vivo minimum detection limit (MDL) was estimated to be 1.0 µg Gd g−1 bone mineral determined from single measurements of low concentration gadolinium hydroxyapatite (HAp) calibration standards. It was thought that the average of 60 measurements at 24-minutes (equivalent to 24-hours) may improve the detection limit and signal to noise ratio (SNR). 

Curve fitting procedures applied to the 24-minute spectrum reduced the uncertainty in measurement. Detection limits from a simple averaging method were compared to the application of the inverse variance weighted mean (IVWM). The IVWM is an aggregating method that could be considered a system optimization with 60 replicates. In either case, with the assumption that gadolinium was uniformly distributed in the phantom material, the MDL was estimated to be 0.8 µg Gd g−1 bone mineral from the aggregate methods.
Is Self-Compassion an Effective Strategy for Improving Body Image and Related Constructs among Women with Normal Weight and Excess Weight?
Authors: Nightingale Bethany
Published: September 2023

Negative attitudes towards one’s own body are common amongst women in Western society and have been linked to adverse consequences including negative affect, low self-esteem, and eating pathology. Self-compassion has been found effective in improving body image; however, no published studies have examined self-compassion in populations with excess weight despite the positive correlation between weight and body dissatisfaction. The current study examined the efficacy of a self-compassion exercise in participants with negative body image and either normal or excess weight to determine whether self-compassion differently affects body image, affect, and self-esteem across weight groups. The self-compassion exercise promoted more adaptive body image and self-compassion than the control condition for those with high weight bias internalization (WBI; i.e., internalization of society’s negative stigma against those with excess weight). Additionally, WBI was significantly related to less adaptive levels of outcome variables regardless of condition. Implications for future body image interventions are discussed.
The Role of Some Affective Factors in Language Learning during Covid-19 Distance Education among English Department Students
Authors: Mrabti Adnane , Benhima Mohamed
Published: September 2023

This study aims to investigate the role of psychological factors or affective factors on language learning during Covid-19 distance education. Both the quantitative and qualitative approaches are used in the current study. The research instruments were questionnaires with one hundred students, and interviews with three students. The results show that motivation, anxiety, attitude, self-confidence, and self-efficacy in learning English are correlated and affected by Covid-19 distance education Hence, it is recommended that the psychological factors of learning should be taken into account by the teacher, administrators and decision makers.
The Randomised Evaluation of early topical Lidocaine patches In Elderly patients admitted to hospital with rib Fractures (RELIEF): feasibility trial protocol
Authors: Lewis Amanda , Clout Madeleine , Benger Jonathan , Braude Philip , Turner Nicholas , Gagg James , Gendall Emma , Holloway Simon , Ingram Jenny , Kandiyali Rebecca , Maskell Nick , Shipway David , Smith Jason E , Taylor Jodi , Darweish-Medniuk Alia , Carlton Edward
Published: September 2023

Background: Topical lidocaine patches, applied over rib fractures, have been suggested as a non-invasive method of local anaesthetic delivery to improve respiratory function, reduce opioid consumption and consequently reduce pulmonary complications. Older patients may gain most benefit from improved analgesic regimens yet lidocaine patches are untested as an early intervention in the Emergency Department (ED). The aim of this trial is to investigate uncertainties around trial design and conduct, to establish whether a definitive randomised trial of topical lidocaine patches in older patients with rib fractures is feasible.

Methods: RELIEF is an open label, multicentre, parallel group, individually randomised, feasibility randomised controlled trial with economic scoping and nested qualitative study. Patients aged ≥ 65 years presenting to the ED with traumatic rib fracture(s) requiring admission will be randomised 1:1 to lidocaine patches (intervention), in addition to standard clinical management, or standard clinical management alone. Lidocaine patches will be applied immediately after diagnosis in ED and continued daily for 72 hours or until discharge. Feasibility outcomes will focus on recruitment, adherence and follow-up data with a total sample size of 100. Clinical outcomes, such as 30-day pulmonary complications, and resource use will be collected to understand feasibility of data collection. Qualitative interviews will explore details of the trial design, trial acceptability and recruitment processes. An evaluation of the feasibility of measuring health economics outcomes data will be completed.

Discussion: Interventions to improve outcomes in elderly patients with rib fractures are urgently required. This feasibility trial will test a novel early intervention which has the potential of fulfilling this unmet need. The Randomised Evaluation of early topical Lidocaine patches In Elderly patients admitted to hospital with rib Fractures (RELIEF) feasibility trial will determine whether a definitive trial is feasible.

ISRCTN Registration: ISRCTN14813929 (22/04/2021).
Nanoformulation of Therapeutic Enzymes: A Short Review
Authors: Tóth Gergő Dániel , Koplányi Gábor , Kenéz Balázs , Balogh-Weiser Diána
Published: September 2023

Enzyme replacement therapy (ERT) is a therapeutic approach that involves the administration of specific enzymes to the patient in order to correct metabolic defects caused by enzyme deficiency. The formulation of ERTs involves the production, purification, and formulation of the enzyme into a stable and biologically active drug product, often using recombinant DNA technology. Non-systemic ERTs often involve the immobilization of the enzyme on a carrier, such as hydrogels, liposomes, or nanoparticles. ERT holds great promise for the treatment of a wide range of genetic disorders, and its success regarding lysosomal storage diseases, such as Fabry disease, Gaucher disease, and Pompe disease has paved the way for the development of similar therapies for other genetic disorders too.
Pembuatan Pelindung Gadget Berbahan Perca untuk Meningkatkan Kreativitas yang Bernilai Ekonomis Bagi Remaja Panti Asuhan Al-Muthi’in
Authors: Mahanani Chytra , Jerusalem Moh. Adam , Himmah Laila Nurul , Elvera Resi Sepsilia
Published: September 2023

In the era of the coronavirus pandemic, people are required to reduce outdoor activities, which affects the economy. One of the efforts to recover economic conditions is by providing skills training and knowledge about creative industries that can be used as capital to increase income. The environment around Al-Muthi'in Orphanage has many resources that can be raised to be developed in the form of creative industries, one of which is the waste of patchwork produced by small fashion industries in Yogyakarta. Creativity and innovation of the students of Al-Muthi'in orphanage need to be developed to capture the opportunities around it. The purpose of training is to increase the creativity of handicrafts of economic value, provide knowledge and insight into the entrepreneurial spirit of the youth of Al-Muthi'in Orphanage so that it can be worth selling, and open home industry opportunities for teenagers Al-Muthi'in Orphanage as an effort to improve the welfare of the family. The target of this activity is the youth of Al-Muthiin Orphanage in Maguwo village, Wonocatur Banguntapan Bantul. The methods used are lectures, demonstrations, training, and practice. The results of the manufacture of gadget-protecting products made of patchwork show that participants understand and are enthusiastic about the manufacture of such products. Through this training, the orphanage youth have the skills to improve the quality of human resources that they can develop to open businesses while creating jobs.
Pelatihan Pembuatan Video Audio Visual Sebagai Inovasi Pembelajaran, Media Ekspresi dan Penunjang Siswa pada Mata Pelajaran Seni Budaya Di SMP Negeri 1 Jatirogo
Authors: Dite Stri Agneyastra
Published: September 2023

Practically, the subject of Culture and Arts at schools is closely related to the advancement of information technology. However, the utilization remains low, causing the instructional process to be less innovative. Knowledge of art and culture in the subject should be an expressive, interactive, and dynamic lesson if technology is used as one of the teaching-learning media. One example is the creation of audiovisual videos about art and culture. A training was created for selected junior high school students at SMP Negeri 1 Jatirogo to make audiovisual short films. The purpose is to teach knowledge on using one of the latest advancements in information technology, particularly audiovisual video, and a participative learning experience that differs from past techniques. The approach employed is participatory, with students serving as learning resources to improve soft skills and abilities in processing and applying concepts in audiovisual form and training to be autonomous and responsible in the learning process. The outcomes of this program provide new ideas for instructors, particularly Cultural and Arts teachers, to create further learning innovations for more engaging, expressive, and apprehensible class meetings through audiovisuals. Another outcome is that students gain diverse learning experiences, including an understanding of short filmmaking, which is another approach to incorporating arts into learning, particularly in Culture and Arts.
Learning Style Preferences of First-Year Residents in Various Medical Specialties in Ramathibodi Hospital, Thailand
Authors: Kiatthanabumrung Sivaporn , Tangbumrungtham Navarat , Wisupagan Tosaphon , Hunlerd Chonticha , Thanoorak Ratree , Mahathanaruk Nilnetre
Published: September 2023

Background: Learning styles preferences play an important role in helping learners acquire knowledge. Because each individual establishes different learning styles, knowing students’ learning preference may help instructors design appropriate teaching methods which aids students to achieve learning outcome more effectively.
Objective: To determine the learning styles in first-year residents of various medical specialties, using the VARK model.
Methods: This cross-sectional descriptive study recruited all first-year residents of academic year 2021 to 2022, at Ramathibodi Hospital. Ninety-five residents gave their consent and submitted the VARK questionnaire. The results were classified into 3 groups of specialties, based on its major characteristics being surgery-based, cognitive-based, or diagnostic-procedure-based.
Results: The VARK preferences in the surgery-based group were as followed; 7.9% aural learners, 26.3% kinesthetic learners, and 65.8% multimodal learners, with none being visual and read/write learners. In the cognitive-based group, the VARK preferences were 7.7% visual learners, 19.2% aural learners, 3.8% read/write learners, 19.2% kinesthetic learners, and 50.0% multimodal learners. In the diagnostic-procedure-based group, the VARK preferences were 8.3% visual learners, 37.5% kinesthetic learners, and 54.2% multimodal learners with none being aural and read/write learners.
Conclusions: The VARK preferences showed that Ramathibodi’s overall first-year residents were mostly multimodal learners with the surgery-based and the diagnostic-procedure-based groups having more kinesthetic preference learners in their specialties.
ความชุก ปัจจัยที่เกี่ยวข้อง และปัจจัยที่มีผลต่อการเข้ารับการรักษาภาวะซึมเศร้าในนักศึกษาแพทย์ชั้นคลินิก โรงพยาบาลแห่งหนึ่งในภาคใต้ของประเทศไทย
Authors: แซ่ไว่ ชัชวาล
Published: September 2023

บทนำ: ภาวะซึมเศร้าเป็นปัญหาสุขภาพจิตที่สำคัญในนักศึกษาแพทย์ ส่งผลต่อประสิทธิภาพในการเรียน คุณภาพการดูแลผู้ป่วย ความปลอดภัยของผู้ป่วย และยังเป็นสาเหตุหลักในการฆ่าตัวตายอีกด้วย
วัตถุประสงค์: เพื่อศึกษาความชุก ปัจจัยที่เกี่ยวข้อง และปัจจัยที่มีผลต่อการเข้ารับการรักษาภาวะซึมเศร้า
วิธีการศึกษา: การศึกษาภาคตัดขวางในกลุ่มตัวอย่างนักศึกษาแพทย์ชั้นคลินิก ชั้นปีที่ 4 ถึง 6 ศูนย์แพทยศาสตรศึกษาชั้นคลินิก โรงพยาบาลมหาราชนครศรีธรรมราช ในช่วงเดือนธันวาคม พ.ศ. 2565 จำนวน 96 คน เก็บข้อมูลจากแบบสอบถามเพื่อประเมินภาวะซึมเศร้า (9-item Patient Health Questionnaire, PHQ-9) การวิเคราะห์ความสัมพันธ์กับปัจจัยต่าง ๆ ใช้การวิเคราะห์การถดถอยพหุแบบโลจิสติก และสอบถามปัจจัยที่ทำให้ไม่เลือกเข้ารับการรักษาในนักศึกษาแพทย์ที่มีภาวะซึมเศร้า
ผลการศึกษา: กลุ่มตัวอย่างทั้งหมด จำนวน 96 คน ตอบแบบสอบถาม คิดเป็นร้อยละ 91.67 (88/96) พบความชุกภาวะซึมเศร้า คิดเป็นร้อยละ 42 (37/88) ปัจจัยที่ส่งผลต่อการเกิดภาวะซึมเศร้า ได้แก่ เพศหญิง (Adjusted OR, 11.36; 95% CI, 2.21 - 46.51) การศึกษาอยู่ในรายวิชาหลัก (Adjusted OR, 6.89; 95% CI, 1.82 - 26.09) และการได้รับข้อมูลไม่เพียงพอของการติดเชื้อไวรัสโคโรนา 2019 หรือโรคโควิด 19 (Adjusted OR, 6.21; 95% CI, 1.58 - 23.81) นักศึกษาแพทย์ที่มีภาวะซึมเศร้า จำนวน 9 คน เลือกไม่เข้ารับการรักษา เนื่องจากรูปแบบการให้บริการไม่เหมาะสม
สรุป: นักศึกษาแพทย์ร้อยละ 42 มีภาวะซึมเศร้า ปัจจัยที่สัมพันธ์กับภาวะซึมเศร้าได้แก่ เพศหญิง การศึกษาอยู่ในรายวิชาหลัก และการได้รับข้อมูลไม่เพียงพอของโรคโควิด 19
Liga acadêmica de saúde da mulher: Empoderamento feminino, promoção de saúde e qualificação profissional
Authors: Pontes Brenda Freitas , Silva Belisa Maria Santos da , Paixão Thayná de Oliveira , Souza Beatriz Garcia de , Quitete Jane Baptista , Jesus Laelma de , Silvério Luana Zaine Aleixo
Published: September 2023

O empoderamento feminino e o reconhecimento do papel da mulher e seus direitos são de suma importância para o desenvolvimento global e os direitos humanos, fato consolidado com o Objetivo de Desenvolvimento Sustentável. As ligas acadêmicas são importantes ferramentas de ensino, pesquisa e extensão dentro da graduação, e possibilitam aprimoramento da autonomia discente. O presente artigo objetiva relatar a experiência de atuação de uma liga acadêmica de saúde da mulher na promoção da saúde, com enfoque na saúde da mulher e o empoderamento feminino. Trata-se de um estudo descritivo do tipo relato de experiência acerca de uma liga acadêmica com enfoque na saúde da mulher e o empoderamento feminino e promoção de saúde, por meio da produção de conteúdo informativo/educativo distribuído em plataformas digitais e oferta de eventos científicos. As ligas acadêmicas são de suma relevância para a formação baseada no ensino tripé ensino, pesquisa e extensão. O oferecimento de cursos de atualização e congressos nacionais é um modo de promover o diálogo e troca de saberes sobre saúde da mulher entre profissionais da saúde e estudantes a fim de levar informação baseada em evidências aos profissionais de saúde. Desse modo, consideramos as mídias sociais como um instrumento de grande relevância para a promoção da saúde da mulher, assegurando um maior alcance de informações para a sociedade no que se refere à saúde e empoderamento feminino. A construção do conhecimento deve ser aprimorada priorizando a diversidade social.
Identificação de potenciais riscos de reações adversas do carbonato de lítio
Authors: Carvalho Bruna Damas de , Zanol Thiago Sales , Meireles Ana Laura Rezende , Matta Raíssa Arruda , Santos Leticia Maria Ribeiro , Sassaki Gabrielly Thiemmy , Machado Elias Inácio Mendonça , Oliveira Izabel Rezende Ferreira Jácomo de , Silva Gabriela Falone , Teodoro Miguel de Faria
Published: September 2023

Introdução: o lítio é a terapêutica em longo prazo mais eficiente no tratamento e prevenção dos transtornos bipolares como estabilizador do humor, e quando em uso, é necessário que haja monitoramento constante da concentração plasmática para evitar casos de intoxicações, pois se trata de substância de baixo índice terapêutico. Objetivo: identificar os potenciais riscos de reações adversas orgânicas e sistemáticas ao carbonato de lítio, bem como as interações medicamentosas que podem corroborar em complicações graves ao paciente. Metodologia: trata-se de uma pesquisa descritiva do tipo Revisão Integrativa de Literatura. Foram considerados estudos publicados no período compreendido entre 2015 e 2021, e analisadas fontes relevantes inerentes ao tema, utilizando como um dos principais critérios a escolha de artigos atuais, originais e internacionais. Resultados: mesmo fazendo o uso em doses terapêuticas, o lítio pode causar alterações importantes, como diminuição da TFG, que de forma retroalimentativa levam a intoxicação aguda por lítio, gerando quadros de alterações cardíacas, renais e do estado mental. Fatores como idade e tempo de uso do fármaco devem ser considerados de forma diretamente proporcional para se avaliar a extensão das lesões e alterações sofridas pelo paciente. Conclusão: apesar de todos os efeitos adversos decorrentes do uso do lítio, esse tratamento segue sendo o padrão ouro no tratamento de transtorno bipolar. Sendo assim, é importante monitorar a litemia dos pacientes e as funções dos múltiplos sistemas a fim de se regular as doses ou mesmo associar o lítio a outros medicamentos a fim de reduzir os efeitos adversos, se necessário.
Funcionamiento de una pirámide financiera mediante un modelo de dinámica de sistemas
Authors: Echeverri E Rubén Darío , Franco Montoya Luz Marina
Published: September 2023

Las pirámides financieras comúnmente colapsan; la literatura ha empleado varios métodos matemáticos para explicarlo. Este artículo emplea una metodología diferente para explicar el auge y las crisis de las pirámides financieras. La metodología integra dos disciplinas: dinámica de sistemas y un método de análisis de epidemias llamado SIR. El artículo tiene como objetivo general desarrollar un modelo de dinámica de sistemas para determinar el umbral de un esquema piramidal. Se concluye que la disminución de los clientes potenciales y, por ello, la disminución de clientes nuevos que entren al negocio es la principal explicación del colapso de dichas pirámides.
Gestión del conocimiento y la competitividad en la industria aeroespacial
Authors: Baltazar J. Leoncio Baltazar , Cárdenas P. Maribel , Ontiveros Alberto , Hernández Laura
Published: September 2023

Este artículo analiza el papel de la gestión del conocimiento en la competitividad de la industria aeroespacial. Utiliza una metodología cuantitativa de alcance correlacional. Se estudia una empresa del apartado 33641 del Sistema de Clasificación para América del Norte (SCIAN). Se aplicó un cuestionario de 24 ítems valorados con escala Likert (Alpha de Cronbach = .945, gestión del conocimiento = .927 y competitividad = .915) dirigido al personal de la empresa en 3 rubros clave: personal directivo, operativo y de soporte. La gestión del conocimiento se estudia desde la propuesta teórica de Probst; la competitividad, desde el Mapa de Competitividad del Banco Interamericano de Desarrollo. Los resultados encontrados exhiben una relación moderada entre los procesos de gestión del conocimiento y la competitividad de la empresa. Se observan limitaciones por el tipo de estructura organizativa y los procesos de alta tecnología que desarrolla la empresa.
Trabajo y vida precaria en pandemia
Authors: Torres Lubin , Oquendo Puerta Sergio René , Córdoba Juan Fernando
Published: September 2023

Este artículo describe las condiciones socioeconómicas de vida y trabajo en el marco de la pandemia covid-19, de un grupo de vendedores informales de la ciudad de Medellín. En el estudio empírico-analítico con el método descriptivo, se aplicó una encuesta a una muestra aleatoria de 273 vendedores. Entre los principales resultados se destacan: la alta proporción de mujeres en este oficio, la mayoría cabeza de hogar; una importante presencia de migrantes, en su mayoría jóvenes entre 25 y 39 años, y también una mayoría proveniente de los barrios con mayores pobrezas de la ciudad. En general, se encontró una población con alta vulnerabilidad social y económica en el contexto de la pandemia, así como una alta desprotección por parte del Estado.
problemática del trabajo infantil desde una mirada cultural
Authors: Ferreño Laura Marisa , Giménez María Laura
Published: September 2023

El empleo de las infancias en el cultivo de tabaco relata situaciones de pobreza que interpelan el cumplimiento de garantías sociales contenidas en el marco legal que regula el trabajo infantil.  El trabajo de campo en las zonas tabacaleras de El Jardín y Rosario de Lerma en la Provincia de Salta (Argentina) reveló que esta práctica social descansa en la dimensión cultural del trabajo infantil, la cual no fue contemplada en las acciones ejecutadas desde la política estatal y las asociaciones civiles. Los primeros resultados evidenciaron que el trabajo infantil es una de las variables que materializa las concepciones hegemónicas en las zonas rurales, amparado en un sistema de oportunidades y favores, de dones y de contradones, de ayuda recíproca entre pares, y naturalizado en la estrategia de reproducción parental.
A study on modeling growth model of Adana pigeons
Authors: ÖZBEK Levent
Published: September 2023

The study aims to determine a mathematical model that can be used to describe the growth of the Adana pigeon. Since pigeons have only one breeding season, just one or two pairs of baby pigeons are raised per year. Hatchlings sometimes die before reaching adulthood. For this reason, measurements can be taken for 10, 15 and 60 days periods. Related with this issue, only 43-days measurements of 68 pigeons are used over a 6-year period. The study is modelled by taking the day-to-day average of the data (43 days) of 68 pigeons. The study was conducted on 68 Adana pigeons in the interval between the age of 1 and 43 days. The growth of pigeon cub was measured by daily live weight until 1 to 43 days. The estimation is carried out by writing the specific Matlab codes. Classical growth functions used in animals are in nonlinear form. Various numerical methods have been developed to estimate parameters in nonlinear functions. Special program routines have been developed to implement these methods. In these nonlinear models, there are more than one parameter to be estimated. Therefore, the number of mathematical operations in estimating the parameters is large. The most used models in the literature are Brody, Bertalanffy, Logistic, Generalized Logistic, Gompertz, Richards, Negative Exponential, Stevens, and Tanaka. However, as far as is known, there is no published article for Adana pigeons that uses all of these models and compares which one is better. These models are Brody, Bertalanffy, Logistic, Generalized Logistic, Gompertz, Richards, Negative Exponential, Stevens, and Tanaka. The best analysis was done by the Richards model in terms of both the Mean Squared Error (MSE), mean absolute percentage error (MAPE) and (Coefficient of Determination) R2 .
Formar och förargar – lärplattform som redskap för återkoppling
Authors: Grönlund Agneta
Published: September 2023

Den digitaliserade skolan har förändrat betingelserna för lärare och elever på många sätt. I följande text riktas fokus mot lärares återkoppling till elever via digitala lärplattformar. Återkoppling i lärplattform ser delvis annorlunda ut än återkoppling som ges ”på papper”. Den är mer standardiserad genom de funktioner som finns i plattformarna. Det sker också en sammanblandning mellan återkoppling och betygsdokumentation som ger återkopplingen en tydligt summativ karaktär. Riktlinjer om återkoppling i lärplattformar beskrivs som en källa till oenighet i kollegier.
A systematic review and meta-analysis of Comaneci/Cascade temporary neck bridging devices for the treatment of intracranial aneurysms
Authors: Sun Bowen , Lan Shuai , Sawant Harshal , Li Yuchen , Ling Yeping , Zhang Bohan , Wu Pei , Wang Chunlei , Shi Huaizhang , Xu Shancai
Published: September 2023

Background

The temporary neck bridging devices represented by Comaneci and Cascade are a type of promising endovascular device for the treatment of intracranial bifurcation or wide-necked aneurysms. This systematic review and meta-analysis aim to assess the efficacy and safety of Comaneci/Cascade devices for the treatment of intracranial aneurysms.

Methods

We performed a systematic literature search on articles in PubMed, Embase, and Web of Science that evaluated the efficacy and safety of Comaneci/Cascade devices for endovascular treatment of intracranial aneurysms, based on the Preferred Reporting Items for Systematic Reviews and Meta Analytics (PRISMA) guideline. We extracted the characteristics and treatment related information of patients included in the study, recorded the rate of technical success, procedural related complications, and angiographic outcomes. The angiographic outcome was evaluated based on Raymond Roy classification, and adequate occlusion was defined as Raymond Ray I + II.

Results

Nine studies comprising 253 patients with 255 aneurysms were included. Among them, eight studies were conducted in Europe, one study was conducted in the USA. All these studies were retrospective. 206 aneurysms (80.78%) were ruptured. The vast majority of patients with ruptured aneurysms did not receive antiplatelet therapy. The rate of technical success was 97.1% (95% CI, 94.9 to 99.3%, I2 = 0%). The rate of periprocedural clinical complications was 10.9% (95% CI, 5.4 to 22.1%, I2 = 54%). The rate of complete occlusion (RR1) and adequate occlusion (RR1 + RR2) on immediate angiography after the procedure were 77.7% (95% CI, 72.7 to 83.2%, I2 = 35%) and 98% (95% CI, 95.9 to 100%, I2 = 0%) respectively. The rate of complete occlusion (RR1) and adequate occlusion (RR1 + RR2) on the last follow-up angiography were 81.2% (95% CI, 69.2 to 95.2%, I2 = 81%) and 93.7% (95% CI, 85.6 to 100%, I2 = 69%) respectively, with follow-up range from 3 to 18 months. 22/187 (11.76%) cases of aneurysms progressed during the follow-up period. 39/187 (20.86%) cases of aneurysms received additional treatment during the follow-up period. No fatal complications occurred during the treatment.

Conclusion

The Comaneci/Cascade device can be used as an auxiliary treatment for intracranial aneurysms, with a good occlusion effect, but the incidence of complications still needs to be monitored.
Resection of Eloquent Located Brain Tumors by Mapping Only—A Feasibility Study
Authors: Staub-Bartelt Franziska , Rapp Marion , Sabel Michael
Published: September 2023

Background: Patients with eloquently located cerebral lesions require surgery that usually employs mapping and monitoring techniques for the preservation of motor and language function. However, in many cases, mapping only might be sufficient, reducing the need for technical and personnel logistics. Here, we report our experiences using a device that can be operated by the surgeon independently, providing mapping techniques but omitting monitoring techniques. Methods: For monopolar and bipolar cortical/subcortical stimulation, pre-set programs were available and intraoperatively used—two enabling EMG real-time tracking of eight muscles for monopolar (cortical/subcortical) mapping, and two programs for 60 Hz stimulation, one with EMG and one without. Motor mapping was performed under continuous observation of the screened EMG signal and acoustic feedback by the surgeon. For the 60 Hz stimulation, a standard bipolar stimulation probe was connected through a second port. The preoperative application of the subdermal EMG needles, as well as the intraoperative handling of the device, were performed by the surgeons independently. Postoperatively, an evaluation of the autonomous handling and feasibility of the device for the chosen test parameters was conducted. Results: From 04/19–09/21, 136 procedures in patients with eloquently located cerebral lesions were performed by using the “mapping-only” device. Mapping was performed in 82% of the monopolar cases and in 42% of the bipolar cases. Regarding the setup and sufficiency for the cortical/subcortical mapping, the device was evaluated as independently usable for motor and language mapping in 129 procedures (95%). Gross total resection was achieved, or functional limit throughout resection was reached, in 79% of the patients. 13 patients postoperatively suffered from a new neurological deficit. At the 3–6-month follow-up, three patients showed persistent deficit (2%). All of them had language disturbances. The setup time for the device was less than 7 min. Conclusions: The device was evaluated as sufficient in over 90% of cases concerning monopolar and bipolar mapping, and the setup and handling was sufficient in all patients. With the present data we show that in well-selected cases, a very simple system providing mapping only is sufficient to achieve gross total resection with the preservation of functionality.
Logics of Discovery II: Lessons from Poetry—Parataxis as a Method That Can Complement the Narrative Compulsion in Vogue in Contemporary Mental Health Care
Authors: Stanghellini Giovanni
Published: September 2023

This paper highlights the limitations of narrative logic in mental health care, and in particular of “narrative vigilance”—the tendency to watch over experience via narrativisation, and to tether the concrete particulars of experience to the hypothetical structure of a narrative signification. Narrative logic is grounded in hypotaxis—the syntactic structuring whereby a discourse is characterised by different levels of subordination using linking words that connect, especially in terms of temporal and explanatory consequentiality. I offer an alternative approach based on parataxis—the practice of placing phrases or parts of speech next to each other without subordinating conjunctions. Sentences are juxtaposed without a clear connection; the contrast may generate novel and unexpected combinations between these dissimilar fragments. After distinguishing between parataxis and psychopathological phenomena like disturbances of association, I take inspiration from the work and life of a poet, Johann Christian Friedrich Hölderlin (1770–1843), considered among the greatest. He suffered for half his life from a severe form of mental illness that would perhaps, today, be diagnosed as schizophrenia. In the poems written during his illness, hypotaxis and narrative vigilance seem to blur, and parataxis takes centre stage. The fading of narrative structure in no way coincides with the absence of meaningfulness. Rather, meaningfulness is left to parataxis itself, that is, to the recombining power of words, sentences, and images. Parataxis itself can provide meaningfulness or, at least, provide the soil in which it can germinate. The void of narration opens the door for the fullness of “emergent” connections. In the final part of the paper, with the help of Freud’s ideas on the relationship between “analysis” and “synthesis” in psychoanalytic treatment, some implications are derived about the relevance of parataxis to the logics of discovery in psychotherapeutic care, especially that of persons with severe mental conditions.
Challenges Faced in Dental Care Delivery Amid Financial Crisis in Sri Lanka: An Evidence-Based Analysis from the Perspective of Health Professionals
Authors: Jayasinghe Yovanthi Anurangi , Jayawickrama Shalindu Malshan , Ratnapreya Sakuntha , Jayasinghe Rasika Manori , De Silva Dileep , Jayasinghe Ruwan Duminda
Published: September 2023

Over the years, Sri Lanka achieved excellent scores in health indicators relative to the national expenditure on health. However, due to several challenging situations such as the 2019 Easter bombings, COVID-19 pandemic and economic crisis, there was a depletion of the GDP as well as rising inflation. This created a humanitarian crisis for all socioeconomic groups. Among them, the health sector was widely affected, including healthcare providers and healthcare recipients. The objective of this study was to elaborate on the challenges faced in dental care delivery by private general dental practitioners and the impact on dental education for undergraduate and postgraduate dental students during the economic crisis. A descriptive cross-sectional survey-based questionnaire (n = 28) was conducted and assessed among the dental surgeons of various districts in Sri Lanka. An interviewer-based questionnaire was carried out via telephone conversation by the principal investigator of dental surgeons for those who managed and owned the respective dental clinic. Data from the computed questionnaires were analyzed using the SPSS Statistical Software Package (SPSS, Version 21). Descriptive statistics were expressed as frequency distributions and percentages. Based on the results, a significant decrease was observed in the number of patients requesting restorative dental procedures including implant crowns (36.29%), implant over dentures (35.63%), crowns (39.03%), bridges (49.12%), amalgam restorations (47.38%), composite restorations (42.11%) and dentures (49.69%). In surgical dental treatment, the extractions and surgical removal of teeth were reduced by 2.11% and 43.71%, respectively. The availability of dental materials such as light care composite (LCC) bonding, silver amalgam, impression materials and surgical consumables was reduced in the post-economic crisis situation compared to the pre-economic crisis status. Furthermore, dental laboratory charges per item, fees per procedure, salaries to support staff, utility bills including electricity and water, payments to government bodies, travelling costs to the clinic (for the doctor) and other expenses have increased in the post-economic period.
Predicting Return to Work after Head and Neck Cancer Treatment Is Challenging Due to Factors That Affect Work Ability
Authors: Tiblom Ehrsson Ylva , Kisiel Marta A. , Yang Yukai , Laurell Göran
Published: September 2023

Striving to return to work is of great importance to many cancer survivors. The purpose of the study is to prospectively investigate the factors that hinder and facilitate return to work (RTW) at 3 and 12 months after the end of treatment in head and neck cancer (HNC) survivors and whether these factors influence the ability to continue working after treatment. Participants (n = 227) aged ≤ 65 years at diagnosis with HNC were included. Data were collected before the start of treatment and at 3 and 12 months after the end of treatment. The Rubin causal model was used for statistical analysis. Within the 3-month follow-up period, 92 participants had RTW and 30 had retired. At the 12-month follow-up, 80 of these participants were still working, another 51 participants had RTW, and five participants working still suffered from cancer. The hindrance to RTW within 3 months was advanced tumour stage (stage III and IV) (p = 0.0038). Hindrances to RTW at the 12-month follow-up were oral cancer (p = 0.0210) and larynx cancer (p = 0.0041), and facilitators were living in a relationship (p = 0.0445) and a white-collar job (p = 0.00267). Participants with early tumour stage (stage I and II) (p = 0.0019) and a white-collar job (p = 0.0185) had earlier RTW. The conclusion is that disease factors were the most important hindrances to RTW, and type of work and living with a spouse or partner were nonclinical factors influencing RTW.