bluuebunny/crossref_metadata_2025 huggingface dataset:
Medical rehabilitation of complications after injections of lipolytics
Authors: Ikonnikova Evgeniya V. , Manturova Natalia E. , Kruglova Larisa S.
Published: June 2023

Lipolytic injections are widely used in cosmetology practice. In most cases, they are used to correct the contours of the body, as well as to reduce the amount of fat deposits in the submental area. Side effects after their use are rare and, as a rule, resolve themselves. However, in the case of the use of non-certified medications, the frequency and severity of complications increase sharply, which requires timely and highly qualified therapy.
The article presents overview data concerning the mechanism of action of the main types of lipolytics and their classification, indications and contraindications to lipolytic therapy, reveals the problems of complications that have developed as a result of their use. A description of a clinical case of the development of an inflammatory reaction after injection of a low-quality lipolytic in the area of paint fat bags is presented. The tactics of her therapy are described. This clinical case demonstrates the importance of using certified products, compliance with injection techniques and the correct choice of the patient for this method of cosmetic therapy.
The article is of interest to a wide range of specialists (cosmetologists, dermatovenerologists, plastic surgeons, physiotherapists).
Variable electromagnetic fields in physiotherapy of diseases of the musculoskeletal system
Authors: Byalovsky Yury Yu. , Ivanov Aleksey V. , Rakitina Irina S.
Published: June 2023

Increasing evidence suggests that the exogenous electromagnetic field may be involved in many biological processes of great importance for therapeutic interventions.
It is known that variable electromagnetic fields are a non-invasive, safe and effective therapeutic tool without obvious side effects. Numerous studies have shown that variable electromagnetic fields can become an independent or additional method of treating diseases of the musculoskeletal system. However, several questions remain unresolved. Prior to their widespread clinical application, further research is needed based on well-designed, high-quality studies to standardize treatment parameters and develop an optimal protocol for healthcare decision making.
In this review, we aimed to provide up-to-date data on the mechanism of action, clinical application, and controversy regarding variable electromagnetic fields in the physiotherapy of musculoskeletal disorders.
Personalized physiotherapy of patients with late complications after the introduction of lip fillers
Authors: Aksenenko Irina P. , Gerasimenko Marina Yu.
Published: June 2023

BACKGROUND: Lip contouring with preparations based on synthetic hyaluronic acid is one of the most popular cosmetic procedures. But in recent years, there has been an explosive increase in the number of complications. There are many physiotherapeutic methods for the treatment of late complications of lip contouring. However, currently there are no differentiated approaches to the choice of physiotherapy techniques and their combination with each other, depending on the nature of the filler and the clinical and functional picture of the complication.
AIM: to develop and evaluate the use of personalized physiotherapy in patients with complications after the introduction of lip fillers, taking into account their genetic predisposition.
MATERIAL AND METHODS: The study involved 52 patients aged 3042 years with a diagnosis of "L57.4 Senile atrophy (lethargy) of the skin", who received late complications (local swelling, dry and pale lip skin, filler contouring, soreness, sensitivity change) at the filler injection site. All patients underwent genetic testing on the Cosmetology panel before the start of treatment. There were 3 groups that received physico-pharmacological methods: laserophoresis of longidase, diadinamophoresis of collagenase or a combination of them in the lip area at the filler injection site.
RESULTS: When analyzing the data after the course of treatment, patients with the combined protocol showed a significant improvement in the quality of life, both in the near and long-term research period. This was expressed in a statistically significant decrease in intradermal edema, rapid regression of pain syndrome and more accelerated biodegradation of the superficially injected filler in the main group compared to other study groups/
CONCLUSION: In patients with late local complications after the introduction of hyaluronic acid fillers, the combined protocol with the inclusion of laser-phoresis of longidase and collagenase diadinamophoresis significantly shortens the recovery period, contributes to a faster reduction of local edema, pain, neuropathy phenomena, accelerated biodegradation of the superficially injected filler, and also allows for a stable clinical result. Personalized physiotherapy is an effective factor in relieving complications after lip contouring.
Spatial distribution of soil organic carbon content in the agricultural land uses: Case study at the territory of the Rahoveci municipality, Kosovo
Authors: BRESİLLA Betim , DEMELEZİ Florent , SZEGİ Tamás , GJİNOVCİ Gazmend , XHEMALİ Bekri , HAVOLLİ Valmira , MEHMETİ Sherif
Published: June 2023

Due to the soil formation factors and different geographic areas of Dukagjini Plain, particularly in Rahovec municipality, the variation of soil organic carbon is high. Soil organic carbon (SOC) has a crucial role in the determination of the physical, chemical and biological behaviour of the soil. The most common land use types of this area are vineyards, table grapes, horticulture such as peppers and cabbage, and arable lands such as maize, winter wheat, alfalfa, and meadows. Considering the lack of soil information data in Kosovo, it is necessary to have soil information about this territory. The main objectives of the present study are, therefore: i) to investigate and determine the concentration of the soil organic matter (SOM), SOC, nitrogen (N) and soil pH-H2O, using laboratory analysis, and ii) to show the spatial distribution of SOC, SOM, N and pH using the Kriging and inverse weighting interpolation methods. Spatial variability of soil chemical parameters such as SOM, SOC, N, and pH are important to be interpolated to view the changeable soil properties by kriging and inverse distance weighting method and to generate the continuous sample for site-specific management. Disturbed soil samples were collected from the top soil 0-30 cm and 30-60 cm depth, to determine selected soil chemical parameters, during June-July 2019. A large number of soil samples were collected, 2087 in the first horizon and 2065 in the second. The average of SOC of the first horizon was 0.91%, which variates from 0.07 to 4.06%, while in the second horizon was 0.0 to 2.84%, the average content of N in the first horizon was 0.09%, which variate from 0.01 to 0.60%, while in the second horizon was 0.0 to 0.39%, meanwhile, the average of soil pH-H2O in the first horizon was 7.67, which variates from 4.25 to 9.35, while in the second horizon was 7.79, which variate from 3.25 to 9.30.
Reducing nitrogen fertilizer combined with biochar amendment improves soil quality and increases grain yield in the intensive rice cultivation system
Authors: LONG Vu Van , DUNG Tran Van
Published: June 2023

Intensive rice cultivation for a long time resulted in increasing soil degradation and less yield. This study aimed to evaluate effects of the combining reducing nitrogen fertilizer (N) with biochar amendment on soil chemical properties, rice growth parameters, and grain yield in the rice cultivation system in the Mekong Delta region, Vietnam (VMD). Field experiment was designed in the split-plot design with two factors, including N fertilizer (main plot) and biochar (sub-plot). Two N fertilizer rates were: (N50)—50 kg N ha–1 and (N100)—100 kg N ha–1, which is the farmer's practice. Biochar was amended with three rates: no applied biochar (B0), 5 t ha–1 (B5), and 10 t ha–1 (B10). The results indicated that reducing N fertilizer by 50% combined 5–10 t biochar ha–1 resulted in maintaining soil pH, soil electrical conductivity, soil organic carbon, cation exchange capacity, and rice biomass. Applying biochar at a rate of 5–10 t ha–1 significantly increased the available N, available P, and rice height compared to the treatment with no applied biochar (B0). Rice yield in the treatments applied with 5–10 t ha–1 was significantly higher than the treatment without the use of biochar by 11.6–14.7%. The findings of this study confirmed that reducing 50% N fertilizer combined with 5 t ha–1 or 10 t ha–1 of biochar could improve soil available N, available P, rice growth, and grain yield in intensive rice cultivation systems in the VMD region.
Tillage system and cover crop effects on organic carbon and available nutrient contents in light chestnut soil
Authors: OSPANBAYEV Zhumagali , DOSZHANOVA Ainur , ABDRAZAKOV Yerlan , ZHAPAYEV Rauan , SEMBAYEVA Aisada , ZAKİEVA Araily , YERTAYEVA Zhainagul
Published: June 2023

Optimal use of management systems including tillage and cover crops are recommended to improve available nutrient contents in soils and sustain agricultural production. The effects on organic carbon and available nutrient contents of three tillage methods (conventional tillage, minimum tillage and no-tillage) and different cover crops such as flaxseed oil, buckwheat, soybean, pea, corn, sorghum, spring oilseed rape and sugar beet were evaluated in a short-term experiment on a light chestnut soil in Kazakhstan. Organic carbon and available nutrient contents were measured in the autumn of 2021. The field measurements included the yield of cover crops and input of organic matter into soils with root and other residues of cover crops. In the laboratory, total organic carbon, labile organic carbon, easily hydrolyzable nitrogen (NH4-N), NO3-N, available P and exchangeable K were measured. The results showed that one season of cover crop growth was not enough to find detectable changes in soil organic matter and available nutrient status in light chestnut soils. On the other hand, even in a short-term field experiment period of 3 months, the most labile organic carbon in soil organic carbon was obtained in conventional tillage. Overall, the results show that at least in the short term and under lower drip irrigation rate in summer for the study area, reduced tillage methods (no-tillage and minimum tillage) is suitable in the study area for soybean, corn and sugar beet production after intensive tillage in the previous year.
Simulation of irrigation in southern Ukraine incorporating soil moisture state in evapotranspiration assessments
Authors: BOHAİENKO Vsevolod , MATİASH Tetiana , ROMASHCHENKO Mykhailo
Published: June 2023

The paper studies the accuracy of modeling moisture transport under the conditions of sprinkler irrigation using evapotranspiration assessment methods that take into account the soil moisture conditions. Appropriate modifications of the Penman-Monteith and the Priestley-Taylor models are considered. Moisture transport modeling is performed using the Richards equation in its integer- and fractional-order forms. Parameters identification is performed by the particle swarm optimization algorithm based on the readings of suction pressure sensors. Results for the two periods of 11 and 50 days demonstrate the possibility of up to ~20% increase in the simulation accuracy by using a modified Priestley-Taylor model when the maintained range of moisture content in the root layer is 70%-100% of field capacity. When irrigation maintained the range of 80%-100% of field capacity, moisture content consideration within evapotranspiration assessment models did not enhance simulation accuracy. This confirms the independence of evapotranspiration from soil moisture content at its levels above 80% of field capacity as in this case actual evapotranspiration reaches a level close to the potential one. Scenario modeling of the entire growing season with the subsequent estimation of crop (maize) yield showed that irrigation regimes generated using evapotranspiration models, which take into account soil moisture data, potentially provide higher yields at lower water supply.
The effects of clinoptilolite type of zeolite and synthesised zeolite-enriched fertilizer on yield parameters of Cucumber (Cucumis sativus) plant and some chemical properties in dark chestnut soil
Authors: VASSİLİNA Tursunay , NASİYEV Beybit , RVAİDAROVA Gulnissam , SHİBİKEYEVA Aigerim , SEİTKALİ Nurzikhan , SALYKOVA Akmarzhan , YERTAYEVA Zhainagul
Published: June 2023

Zeolites have been used in agriculture since the 1960s, due to the effectiveness of these crystalline microporous solids as soil amendments for plant growth, their cation exchange capacity (CEC) and slow-release fertilizer properties. Most work on slow-release fertilizers has focused on natural Clinoptilolite, Phillipsite and Chabazite. The aim of this study was to synthesize clinoptilolite type of zeolite-enriched fertilizer study their effectiveness as soil amendments. Greenhouse experiments were performed to study the effects of clinoptilolite type of zeolite, synthesised zeolite-enriched ammophos fertilizer and ammophos fertilizer (12% N, 52% P2O5) on yield parameters of Cucumber (Cucumis sativus) plant and some chemical properties in dark chestnut soil. According to greenhouse experiment results, there were significant differences among the treatments in relation to yield parameters (weight of one cucumber, shoot length, number of leaves, area of 10 leaves, number of fruits and fruit weight per plant) of cucumber and available nutrient contents of soil. It was determined that the yield parameters of cucumber plant, available nutrient contents (N, P and K) and cation exchange capacity were increased the most by synthesised zeolite-enriched fertilizer application.
Main factors in polycyclic aromatic hydrocarbons accumulations in the long-term technogenic contaminated soil
Authors: DUDNİKOVA Tamara , SUSHKOVA Svetlana , MİNKİNA Tatiana , BARBASHEV Andrey , FERREİRA Carla Sofia Santos , ANTONENKO Elena , SHUVAEV Evgenyi , BAKOEVA Gulnora
Published: June 2023

The PAHs transformation in the soils of the coal mining enterprises impact zones and thermal power plants remains poorly studied. In turn, coal mining can be considered as a primary cycle in the production of electricity. One of the main sources of negative environmental impact is the coal mining industry located on the territory of the upland in the south of the East European Plain. The features of PAHs accumulation in the soils of fuel and energy enterprises have been studied on the example of mines impact zones with different service life and the current coal-fired power plant. It was established that, regardless of the period and intensity of the emission source, as well as its current status, the polycyclic aromatic hydrocarbons (PAHs) content in the soils of the impact zones was significantly higher than in the soils of the background territory. The content of low molecular and high molecular weight PAHs in the impact zones soils differed depending on the land use type, as well as the period and intensity of an industrial effect type. The pollutants content of in the soils of all considered impact zones significantly exceeded the background values and according to the low molecular weight PAHs content in the soils, they formed the following decreasing series: Mayskiy ≥ Ayutinsky > Novoshahtinsk > Power station > Background. According the high molecular weight PAHs content, the series changed to: Novoshahtinsk >Mayskiy ≥ Ayutinsky > Power station > Background. Soil pollution markers for enterprises of the fuel and energy complex were identified as pyrene and chrysene, which are part of coal, formed from the hydrocarbon sources. The influence of the power plant was accompanied by the benzo(g,h,i)perylene concentration increase.
The Effect of Memantine Versus Folic Acid on Cognitive Impairment in Patients with Schizophrenia: A Randomized Clinical Trial
Authors: Hosseini Seyed Ahmad , Sepehrmanesh Zahra , Gilasi Hamidreza , Ghoraishi‬ Fatemeh Sadat
Published: June 2023

Objective: Schizophrenia, as one of the most severe psychiatric diseases, has a chronic and debilitating process. The majority of patients with schizophrenia do not respond adequately to treatment with common antipsychotic drugs. Therapeutic problems induced by drug side effects as well as undesired results are major challenging issues regarding this disease. This study aimed at evaluating the effect of memantine supplementation on the improvement of cognitive symptoms in patients with schizophrenia.
Method: The present clinical trial was performed on 50 patients with acute schizophrenia who were admitted to Kargarnejad Psychiatric Hospital in Kashan in 2022 and who were diagnosed as schizophrenia cases at least three months ago. Patients were randomly divided into either the intervention group (n = 25) or the placebo group (n = 25). The intervention group received 5 mg of memantine per day for three months. The dose of memantine in this group was increased to the maximum of 20 mg per day. The placebo group received 1 mg of folic acid per day for three months. Moreover, an identical routine schizophrenia therapeutic regimen was administered to all patients. The effectiveness of memantine was evaluated using the Wechsler Adult Intelligence Scale (WAIS-III), which assessed cognitive ability in older adults over a 12-week follow-up period.
Results: The WAIS-III score in the 12th week of the study was significantly different between the placebo and intervention groups (P = 0.004), such that the score of the memantine group was higher than that of the placebo group. No significant difference was observed between the two groups in terms of drug side effects.
Conclusion: Memantine can be supplemented in the treatment of schizophrenia so as to improve the cognitive symptoms of this disorder. However, subsequent studies involving larger sample sizes and different doses seem to be necessary to provide more accurate results in this respect.
The Relationship between the Structures of Personality Inventory for the Diagnostic and Statistical Manual, Fifth Edition (PID-5) and Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF)
Authors: Ghamkhar Fard Zahra , Shakiba Shima , Mirabzadeh Arash , Pourshahbaz Abbas
Published: June 2023

Objective: The Personality Inventory for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (PID-5), is a trait-based measure of pathological personality designed to assess Criterion B of an alternative diagnostic system for personality disorders (PDs). In this study, we aimed to evaluate the relations among the PID-5 and the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF); a commonly used self-report instrument with a hierarchical structure.
Method: We examined the joint structure of the PID-5 scales along with levels of the MMPI-2-RF hierarchy to understand whether conceptually expected structures tend to be loaded with each other. Data were collected from 536 participants from the general population of Iran.
Results: Findings of Pearson’s correlation analyses exhibited the generally expected patterns between the two mentioned measures on most scales, with some divergences. Similarly, although applying a set of joint exploratory structural equation modeling (ESEM) exhibited some factor loadings for PID-5 facets within the hierarchical framework of MMPI-2-RF scales that were different to what was theoretically expected, both measures were generally loaded in a conceptually expected way, indicating that they have a similar dimensional structure.
Conclusion: Our findings provide support for adequate convergence of maladaptive personality traits and psychopathology structures, as well as for utilizing MMPI-2-RF to measure personality psychopathology from a dimensional perspective. The implications of these results are discussed by the authors.
Cosmetic Breast Implants and the Risk of Suicide: A Systematic Review and Meta-Analysis
Authors: Mousavi Zahra , Abolhasanpour Nasrin , Naseri Amirreza , Maghsoudi Fatemeh , Farshbaf-khalili Azizeh , Shahsavarinia Kavous , Mousavi Ali , Beheshti Rasa , Mostafaei Ali , Salehi-Pourmehr Hanieh
Published: June 2023

Objective: Having cosmetic breast implants increases a woman's chance of suicide, which is now a global challenge.
This systematic review evaluated the possible risk of suicide among women who undergo cosmetic breast implants.
Method: This meta-analysis was done based on Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA). In the current systematic review and meta-analysis, we systematically searched for all articles written in both English or Persian that estimated the prevalence of suicidal ideation in women who had cosmetic breast implants. We systematically searched different databases, including MEDLINE (PubMed), Web of Science, Embase, Cochrane, Library ProQuest, Scopus, and Google Scholar, from inception to March 2021. There was also a search for references. Suicidal ideation, a suicide plan, or suicide attempts were the outcomes. In order to determine the total pooled prevalence of suicidal ideation, we utilized a random-effects model. To examine the risks of bias in each study, we applied the Joanna Briggs Institute Critical Appraisal method.
Results: We identified 218 citations in our initial search. After omitting duplicated citations and excluding irrelevant studies according to the title and abstract selection, 42 studies were chosen for the full text analysis. Finally, 11 research, examining a total of 324,332 women were incorporated into the systematic review and critical appraisal assessment. Eight of these studies were found to be eligible for meta-analysis. The frequency of suicide in women with cosmetic breast implant was 0.2% (95% CI: 0.1% to 0.4%; P < 0.001) (Q-value: 168.143, I2:95.83). Most of the included studies had moderate quality.
Conclusion: There might be a correlation between cosmetic breast implants and suicide risk, which could be stronger in the presence of a history of mental illnesses. The evidence about the possible effects of breast implants.
Recovery-Oriented Practices in Community-based Mental Health Services: A Systematic Review
Authors: Mousavizadeh Seyedeh Narjes , Jandaghian Bidgoli Mohammad Amin
Published: June 2023

Objective: New initiatives are needed to manage patients with mental health problems in the community. Among the core principal ideals of any healthcare system is transition from traditional services to community-based practices. The aim of this study was to assess community-based and recovery-oriented practices and interventions for individuals with mental health problems.
Method: MESH keywords, including “mental health recovery”, “rehabilitation”, “aftercare”, “community psychiatry”, and “mental health service” were searched in scientific databases such as Medline, EMBASE, PsychInfo, CINAHL, and Cochrane up to July 2022. A snowball search was also conducted on eligible studies. The methodological quality of the studies was determined by Kmet standard criteria.
Results: The systematic review included 32 studies, all of which demonstrated a moderate to high promising effect for community-based and recovery-oriented practices or programs on patients with severe mental illness. These practices could help patients to find suitable jobs, avoid isolation and stigma, improve communication skills, increase awareness of problems, and foster independence. The study also highlighted the pivotal role of nurses, artistic and sports activities, electronic (E)-mental health, home visits, psychoeducation, and special recovery programs.
Conclusion: Community-based and recovery-oriented practices should be used as an effective means of normalizing the lives of psychiatric patients. In essence, by cultivating hope and empowering these patients, many of the concerns of health systems can be eradicated.
Effectiveness of Neurofeedback Training for Patients with Personality Disorders: A Systematic Review
Authors: Babaskina Liudmila , Afanasyeva Natalia , Semyonkina Marta , Myasnyankina Olivia , Sushko Natalia
Published: June 2023

Objective: Personality disorders are serious psychiatric conditions, and some studies have examined neurofeedback training as a potential alternative treatment to improve cognitive and clinical symptoms in patients with such disorders. Here, we aimed to provide a first systematic review of such trials and present existing evidence regarding this treatment for individuals with personality disorders.
Method: A systematic search of peer-reviewed English journal articles was conducted for this study to identify original studies on fMRI and EEG neurofeedback treatment protocols in patients with personality disorders up to January 2023. PubMed, Web of Science, ProQuest, Cochrane Library, and Google Scholar databases were queried through the keywords "neurofeedback," "biofeedback," and "personality disorder," as well as their related Mesh synonyms.
Results: Totally, five studies were included in our systematic review. Two studies utilized EEG neurofeedback protocols, while three articles used real-time fMRI neurofeedback protocols. The types of studies were non-randomized, not-blinded case reports, case series, and single-arm trials with a high risk of bias. EEG neurofeedback protocols applied more training sessions and reported improvements in patients' neuropsychological and behavioral functions after treatment. Furthermore, fMRI-based neurofeedback studies reported neurophysiological changes, such as a shift in vmPFC-amygdala connectivity, towards healthy states following treatment. Moreover, behavioral symptoms of patients were reported to be improved after fMRI neurofeedback.
Conclusion: Neurofeedback studies investigating this therapeutic technique for personality disorders are still very preliminary, and no strict conclusions can be drawn at this time. Therefore, further basic and clinical investigations are required to address several open methodological and technical questions and establish consensus and standardization, which will eventually lead to translational works.
Evaluation of the Effect of Barberry Root (Berberis Vulgaris) on the Prevention of Metabolic Syndrome Caused by Atypical Antipsychotic Drugs in Patients with Schizophrenia: A Three-Blind Placebo-Controlled Clinical Trial
Authors: Rostami Hamzeh , Babaali Farzaneh , Moradi Leila , Golfakhrabadi Fereshteh , Abdi Leila
Published: June 2023

Objective: Metabolic syndrome is a potential side effect of atypical antipsychotics which are the current standard treatment for schizophrenia. Therefore, we aimed to examine the effect of barberry root (Berberis vulgaris) on the prevention of metabolic syndrome caused by atypical antipsychotic drugs in patients with schizophrenia.
Method: Our research was a three-blind randomized clinical trial. The participants included all patients who were diagnosed with schizophrenia through the SCID-5 questionnaire and based on the DSM-5-TR criteria by two psychiatric experts. These patients were randomly divided into intervention and placebo groups. During a three-month treatment period, the intervention group received three 500 mg capsules of barberry root extract daily, whereas the placebo group received the same capsules containing 500 mg of starch powder. Metabolic syndrome variables including fasting blood glucose, serum lipids (triglyceride and cholesterol), blood pressure, weight and waist circumference were measured before and after the treatment as outcome measure. Chi-square and t-tests were used for data analysis using SPSS-22 software.
Results: At the beginning of the study, there was no significant difference between the intervention group (n = 41) and the placebo group (n = 47) in terms of demographic factors, and pre-treatment assessments including weight, waist size, fasting blood HDL, fasting blood triglycerides and systolic and diastolic blood pressure and fasting blood glucose (P > 0.05). Within group analysis showed that some metabolic factors significantly increased in both groups after the treatment (P < 0.05). Indeed, in both groups, metabolic syndrome measures worsened after the three-month treatment period. The parameters of weight and waist size were significantly higher in the intervention group than the placebo group after treatment (P < 0.05).
Conclusion: Barberry root extract was not able to control the Effects of antipsychotic drugs on metabolic syndrome in schizophrenia.
Evaluation of Changes in Antioxidant Factors and Albumin Level Following the Administration of a Controlled-Releasing Drug Delivery System of Chitosan Hydrogel Loaded with Buprenorphine and Ketorolac in an Experimental Bone Defect in the Tibia of the Rat
Authors: Javdani Moosa , Khosravian Pegah , Barzegar Abolfazl , Hashemnia Mohammad
Published: June 2023

Full Title: Evaluation of Changes in Antioxidant Factors and Albumin Level Following the Administration of a Controlled-Releasing Drug Delivery System of Chitosan Hydrogel Loaded with Buprenorphine and Ketorolac in an Experimental Bone Defect in the Tibia of the Rat Model 
Background: In the present study, the effectiveness of a controlled-release drug delivery system of chitosan hydrogel loaded with ketorolac and buprenorphine on oxidative stress indices and albumin changes in the experimental bone defect model was considered.
Methods: After creating an experimental defect in the right tibia of each rat, 5 groups, including (A) the control group that did not receive any pharmacological intervention, (B) the chitosan hydrogel receiving group, (C) the group receiving chitosan hydrogel loaded with buprenorphine, (D) the group receiving chitosan hydrogel loaded with ketorolac, and (E) the group receiving chitosan hydrogel loaded with ketorolac and buprenorphine, were considered. Serum concentrations of antioxidant factors and albumin levels were then measured on days 0, 3, 7, and 21 after surgery.
Results: In the control group, the maximum amount of oxidative stress and the maximum activity of antioxidant enzymes on the third and seventh days were compared between the 4 treatment groups. Moreover, the maximum amount of albumin on the third day was recorded and compared between the 4 other treatment groups. In 4 treatment groups, a significant decrease was observed in the mean of parameters related to oxidative stress compared to the control group, which was more noticeable in the group receiving ketorolac.
Conclusion: In the present study, the highest rate of control of oxidative stress conditions was observed in the group treated with the ketorolac-loaded chitosan hydrogel system, possibly due to its antioxidant properties and better control of inflammatory conditions caused by the use of chitosan and ketorolac in this treatment group.
Abnormal Thigh Swelling after Anterior Cruciate Ligament Reconstruction with Tourniquet
Authors: Aslani Hamidreza , Hosseini Seyyed Mehdi , Kouhestani Emad , Bisadi Amir
Published: June 2023

Background: Anterior cruciate ligament (ACL) reconstruction surgery is a common orthopedic procedure. Minimally invasive surgeries and arthroscopy are becoming more common, and tourniquets are utilized in these procedures to reduce bleeding and allow for improved tissue visualization.
Case Report: In this paper, we report a 32-year-old man who underwent the right knee ACL reconstruction using a tourniquet following trauma. He developed thigh swelling at the tourniquet site after surgery. Right thigh ultrasound and magnetic resonance imaging (MRI) indicated extensive interstitial edema in all compartments without collection, hematoma, or hemorrhage. The patient was treated with dexamethasone and Lasix for four days. Rehabilitation activities included exercises to improve range of motion (ROM), strength exercises, and a home workout routine. Two weeks after discharge, the swelling decreased by about 80%.
Conclusion: We believe that using a tourniquet during the reconstruction surgery may be responsible for the extensive edema in the limb. However, despite several diagnostic methods, we could not explain the reason for the edema in the limb following surgery.
Familial Synovial Hypertrophy: A Case Report
Authors: Shayan-Moghadam Ramin , Sharafi Mohammadhasan , Mahmoudi Ehsan , Nabian Mohammad Hossein
Published: June 2023

Background: Familial synovial hypertrophy is a rare condition presenting as the flexion contracture of the small joints of the hands and feet, in addition to the large joint effusion and range of motion (ROM) restriction.
Case Report: Herein, we introduce a 14-year-old boy with a long history of deformities in the hand and foot joints. Painless swelling and limited motion of big joints were present since birth. There were no similar diseases in paternal or maternal relatives, while his 9-year-old brother also had a lifelong history of same deformities.
Conclusion: Involvement of the hands and feet can severely restrict young patients’ function in daily tasks, raising the importance of early diagnosis and treatment in familial synovial hypertrophy.
Effect of Sports Training on Body Mechanics during Transitional Movements in Individuals with Foot Pronation: Literature from 2019-2022
Authors: Piri Ebrahim , Jafarnezhadgero AmirAli , Ebrahimpour Hamed , Nasri Ali
Published: June 2023

Introduction: Pronated foot, as one of the common foot abnormalities can affect the biomechanics of the lower extremity. The purpose of the present study was to investigate the scientific research related to the application of various exercise protocols on foot pronation complications, as well as to make favorable summary and provide more appropriate information from previous research. In this study, the search for articles in Persian and Latin languages in 2019-2022 was carried out on WOS, Magiran, PubMed, Springer databases, and Google Scholar. The number of 52 related articles was selected based on the inclusion and exclusion criteria. After another review on these papers, 18 articles that evaluated the effects of training protocols on body mechanics in individuals with pronated feet were selected.
Conclusion: It seems that performing exercise to improve balance, strengthening the quadriceps muscles, and not change the lower extremity joints angles during activity has been effective. Therefore, it is suggested that rehabilitation professionals consider reinforcement activities in the process of recovering pronated using the principles and science practice.
Evaluation of Problems Related to Complete Denture in Patients Referred to Prosthodontics Department of Birjand Dental College in Years 2018-2020
Authors: Biabanki Farzaneh , Emadian Seyedeh Fariba , Osmani Fereshteh
Published: June 2023

Introduction: Complete denture is a type of dental prosthesis that is used to restore function and beauty in patients with complete edentulousness. Problems after denture delivery are common and involve the patient and the dentist, and post-delivery care is often overlooked by most students and dentists. The aim of this study was to investigate the common problems of the patients with complete dentures referred to the Prosthesis Department of Birjand Dental School and their relationship with variables such as sex, age, etc.
Methods: In this descriptive analytical study 46 patients participated, 26 patients were male and 20 were female. The patients ranged in age from 33 to 90 years. These patients had previously been treated in the ward by students with complete prosthetics. Patients were asked the questions in the questionnaire. After collecting the data, the data were entered into SPSS software version 16 and reported as a percentage of relative frequency. Then, Chi-square or Fisher test was used to examine the relationship between qualitative variables. (P≤0.05).
Results: The results showed that 3 of the most common problems included food retention (52%), lack of retention (50%), and pain (34.8%). But in most cases, there was no significant difference was seen among gender, age, patient motivation to refer, etc.
Conclusion: According to the results, the most common problems after denture delivery are food retention and lack of retention, which need to be reduced to identify the etiology and their causes.
Contribution to the non-destructive evaluation of bituminous mixes by electrical measurements
Authors: Meymouna Messaoud , Bachir Glaoui , Othmane Abdelkhalek , Rabehi Rachid
Published: June 2023

The incorporation of additives into bituminous mixes is a very important technique for improving the mechanical and electrical properties of the pavement body. The purpose of this work is to present and interpret the different results of the tests carried out in the laboratory; such as FENIX direct tensile test and electrical resistivity test. In this work, we will present comparative studies between the mechanical and electrical characteristics of bituminous mixes based on conductive additives (steel fibers and graphite powder). This comparison makes it possible to classify these resulting materials as materials that have the ability to respond to different multifunctional applications.
Effect of sodium lauroyl sarcosinate on the thermal, optical and moisture absorption properties of polyvinylpyrrolidone film
Authors: Caetano Ian Pellinca Braga , Stapelfeldt Danielle Marques de Araújo , Melo Rodrigo de Siqueira , Freitas Kênia da Silva , Shiguihara Ana Lucia , Amim Júnior Jorge
Published: June 2023

In the present study, polyvinylpyrrolidone films containing amino acid-based surfactant, namely, sodium lauroyl sarcosinate (SLS), were prepared by casting method. The obtained films (PVP/SLS) were characterized by means of attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), optical properties, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and moisture absorption (MA). ATR-FTIR spectra of PVP/SLS films showed the main bands of PVP. The opacity of PVP films increased with the addition of SLS. Furthermore, moisture absorption of PVP/SLS films were higher than the pristine PVP film. TGA curves displayed that the thermal stability of PVP film decreased after the incorporation of SLS. DSC curves indicated that SLS can be used as plasticizer for PVP.
Análisis del nicho climático de Coryphantha durangensis (Runge ex Schum.) Britton y Rose, 1923 e identificación de zonas potenciales para su conservación ante el cambio climático
Authors: Estrada-Rodríguez José Luis , Romero-Méndez Ulises , Becerra Jorge , Czaja Alexander , López-Martínez Hugo , Reyes-Muñoz Jesus Lumar , Ávila-Rodríguez Verónica , Cardoza-Martínez Gabriel Fernando , Estrada-Arellano Josué Raymundo
Published: June 2023

Coryphantha durangensis es una cactácea endémica que habita en México, en el centro del desierto Chihuahuense, y está considerada en la categoría de Protección Especial por la NOM-059-SEMARNAT-2010. Una de las mayores amenazas para esta especie es el cambio climático y pérdida de idoneidad climática para su presencia, en el presente estudio se evaluó el nicho climático de C. durangensis y se modeló la disponibilidad climática de esta especie mediante el algoritmo MaxEnt bajo condiciones del clima actual y futuro. Los resultados muestran una reducción en las zonas geográficas que presentan condiciones climáticamente adecuadas para la presencia de esta especie para el año 2050 y 2070. Sin embargo, se identificaron cuatro sitios que podrían ser propuestos como áreas de conservación para ésta y otras especies que cohabitan en estas zonas.
Estimación del riesgo microbiológico asociado al consumo de ostión crudo contaminado con Vibrio cholerae y Vibrio parahaemolyticus
Authors: Lòpez Hernández Karla María , Pardío-Sedas Violeta T. , Flores Primo Argel , Martínez Herrera David Izcoatl , Uscanga Serrano Roxana
Published: June 2023

El objetivo del estudio fue predecir el riesgo potencial de exposición a V. cholerae y V. parahaemolyticus asociado al consumo de ostión americano (Crassostrea virginica) crudo colectado del Sistema Lagunar Mandinga (SLM), en restaurantes, coctelerías y puestos ambulantes. El riesgo se estimó como casos esperados/100,000 porciones con el modelo de la FDA. En ostiones del SLM el riesgo estimado por consumir ostiones contaminados con V. cholerae noO1/noO139 chxA+ sin refrigerar 10 h en verano fue bajo (99×10-5 casos); V. parahaemolyticus tdh+ y tdh+/trh+ representaron un riesgo estimado alto en primavera (2,200×10-5 y 4,000×10-5 casos, respectivamente) y la cepa pandémica orf8+ un riesgo medio (110×10-5 casos) en invierno. El consumo de ostión crudo sin refrigerar 10 h contaminado con V. cholerae noO1/noO139 chxA+ representó un riesgo promedio bajo (0.87×10-5 y 0.44×10-5 casos) para restaurantes y coctelerías, respectivamente, alto para cocteles expendidos en puestos ambulantes a temperatura ambiente 24 h (2,500×10-5 casos) y bajo a V. parahaemolyticus tdh+ en restaurantes (0.21×10-5 casos) y coctelerías (1.1×10-5 casos). El porcentaje patogénico, el sitio de venta y el tiempo sin refrigerar fueron las variables que incrementaron el riesgo de enfermar, siendo primavera la estación con el mayor riesgo para el consumidor.
Propuesta de un modelo de síndrome metabólico en ratones CD1 inducido con una dieta hipercalórica
Authors: Sollano-Mendieta Xóchitl Cruz , Escalona-Cardoso Gerardo Norberto , Cano-Europa Edgar , Paniagua Castro Norma
Published: June 2023

Las enfermedades metabólicas, incluyendo la obesidad y la diabetes mellitus tipo 2, representan un grave problema de salud y mortalidad, en México. La Organización Mundial de la Salud (OMS) y otras asociaciones como la Federación internacional de la Diabetes (IDF) y el Programa Nacional de Educación para el Colesterol-Panel de Tratamiento para el Adulto III (NCEP-ATP III) definen el Síndrome Metabólico (SM), como la agrupación de alteraciones metabólicas que conllevan al desarrollo de obesidad, hipertensión y diabetes mellitus. El objetivo de este estudio fue desarrollar un modelo de SM en roedores CD1 utilizando una dieta hipercalórica y determinar las ventajas y/o desventajas comparado con otros modelos murinos. Se utilizaron ratones CD1 hembras y machos se dividieron en 2 grupos por género, un grupo control y otro grupo con dieta hipercalórica durante 10 semanas. Los resultados obtenidos mostraron que la dieta hipercalórica es eficiente para desarrollar las alteraciones metabólicas presentes en el SM, se observaron mejores resultados en los ratones macho, por lo que se sugiere la utilización en este género para evitar los cambios hormonales presentes en las hembras adultas
Physicochemical, techno-functional and antioxidant characterization of coffee silverskin
Authors: Vargas-Sánchez Rey David , Torres-Martínez Brisa del Mar , Torrescano-Urrutia Gastón Ramón , Sánchez-Escalante Armida
Published: June 2023

Coffee residues have been considered a valuable source of nutritional and functional components thus are considered a potential ingredient for foods. The aim of this study was to evaluate the physicochemical, techno-functional and antioxidant properties of coffee silverskin flakes and powder. The results indicated that coffee silverskin flakes and powder showed pH near to neutrality, and the color was Roman coffee and Deep coffee, respectively, which show that milling process change this parameter. Coffee silverskin flakes showed the highest water and oil-holding capacity, while, both coffee residues exert slight swelling and foam capacity, and foam stability, without effect of milling process. However, both residues do not exert emulsion and gelling capacity, as well as emulsion stability. The presence of phenols, flavonoids, caffeoylquinic acid and alkaloids (powder > flakes) were detected in both residues, which exert free- and radical-cation scavenging activity (powder = flakes), reducing power properties, and lipid oxidation inhibition (powder > flakes). In conclusion, coffee silverskin can be proposed as a functional ingredient for food industry.
Dietary sources, bioavailability and health effects of carotenoids
Authors: Victoria-Campos Claudia I. , Ornelas-Paz Juan , Ruiz-Cruz Saul , Ornelas-Paz José de Jesús , Cervantes-Paz Braulio , Rios-Velasco Claudio , Pérez-Martínez Jaime D. , Gardea-Béjar Alfonso A. , Yahia Elhadi M. , Ibarra-Junquera Vrani
Published: June 2023

Carotenoids are non-polar compounds found in fruits and vegetables. The consumption of these compounds has been associated with many beneficial effects on human health, especially on the prevention of chronic diseases that are currently considered as problems of public health. These effects have mainly been attributed to the antioxidant properties of carotenoids, although many other mechanisms are involved, including the influence of carotenoids in the expression of genes involved in the pathogenesis of these diseases. Unfortunately, the bioavailability of these compounds is very limited. The effects of several factors on carotenoid bioavailability have been studied in order to identify the best strategies to increase the absorption of these compounds and, consequently, their bioactivity. Currently, important efforts have being carried out to determine the content and bioavailability of carotenoids from underutilized foods and the mechanisms involved in their bioavailability and beneficial effects. In this review, the recent findings on carotenoid sources, bioavailability and bioactivity are discussed.
Foreword to the Journal of Food Nutrition Chemistry
Authors: Liu Libing
Published: June 2023

Food is the foundation for human survival and healthy development. People need to eat every day, and obtain the essential nutrients from food in order to promote body growth and development through biochemical process such as digestion, absorption and metabolism. With the increasing concern about health and nutrition, people gradually realize that the nutrients contained in food are critical to our physical functions and overall well-beings. To formulate a proper diet plan, prevent diseases and keep good health, it is critical for us to have a thorough understanding of the nutritional ingredients, functions and chemical interactions of food. Food Nutrition Chemistry is a comprehensive interdisciplinary science, focusing on the nutrients contained in food and their impact on human health, which plays an important role in the field of life and health.
果蔬生物活性成分及功能研究进展
Authors: 王雨贝  , 李世豪  , 李可昕  , 刘佩冶  , 曹建康
Published: June 2023

果蔬是人们重要的食物种类之一。在果蔬中含有种类丰富多样的植物次生代谢产物，有多酚类物质、类黄酮类、蒽醌类、萜类、生物碱、甾体皂苷、多糖等。次生代谢产物往往具有多种的生理活性功能，有抗氧化、抗肿瘤、降血糖、降血脂、神经保护、抗炎、抗菌和预防疾病等方面的生物活性功能。但是，不同种类果蔬中这些产物的组成与含量差异非常大，在活性功能表现与作用机制上也莫衷一是。本文综述了果蔬中主要的生物活性成分及其多功能的研究进展，以促进对果蔬食物功能的开发利用。
天然高产NMN菌株的筛选及Nampt生物合成NMN
Authors: 李超  , 邹国珑  , 张海潮  , 林玉惠  , 赵丽青
Published: June 2023

烟酰胺单核苷酸(NMN)是一种人体内源性物质，具有较高的安全性和热稳定性，其在化妆品、医药健康、功能食品等方面的应用受到广泛关注。然而，NMN的合成过程存在成本高、耗时长、收率低等问题，在一定程度上限制了NMN的大规模工业化应用。烟酰胺磷酸核糖转移酶(Nampt)是NMN生物合成技术路线中的关键酶，可催化烟酰胺(NAM)和焦磷酸磷酸核糖(PRPP)合成NMN。筛选和表达具有优良酶学性质和稳定性的Nampt是该方法合成NMN的关键。目前，Nampt生产NMN的技术路线存在的主要问题是Nampt的催化活性低。而Nampt的来源少且有限，因此我们分离出高产NMN的微生物成都肠杆菌2021T4.7，并优化了其发酵条件。NMN 的产量高达 67.66 μM。此外，我们还合成了Nampt并构建了相关的重组高产工程菌。我们半理性设计了源自小鼠的Nampt结构，获得了突变体mNampt-V365L，NMN产量高达135.99 μM，比野生型提高了62%。在此，我们筛选出高产NMN天然菌株，通过Nampt酶的半理性设计优化得到高产菌株，为NMN的转化率提供了新的底盘微生物和新思路。
Date Of Easter Sebagai Reformasi Kalender Masehi
Authors: Jannah Elly Uzlifatul
Published: June 2023

This research discusses the history of the calculation of the date of Easter as part of the reform of the Gregorian calendar using a historical approach. It examines the history of the determination of the date of Easter by the Council of Nicaea in 325 AD and the use of the ecclesiastical full moon method to calculate the date of Easter. This research also discusses the differences in the dating of Easter in the Julian and Gregorian calendars and the relationship between the dating of Easter and the astronomical vernal equinox. The results of this research show that the date of Easter is calculated based on mathematical calculations, taking into account the ecclesiastical full moon and is no longer related to accurate astronomical calculations. This research provides a clear overview of the history and methods of determining the date of Easter and can serve as a reference for scientists and researchers to further study the reform of the Gregorian calendar and the calculation of the date of Easter.