bluuebunny/crossref_metadata_2025 huggingface dataset:
Efectos de la microvibración a 30 Hz sobre la expresión de IL-17 y RANKL en células osteoblásticas derivadas del cráneo y osteoclastos derivados de la médula ósea cultivadas in vitro
Authors: García López Salvador , Villanueva Arriaga Rosina E. , Pérez Vázquez José Luis , Juárez Noriega Luis Iván , Paéz Arenas Aracely , Felipe Massó Luis , C. Meikle Murray
Published: August 2022

Introducción: Se ha demostrado que utilizar el tratamiento de microvibración en pacientes con osteoporosis induce remodelación en la cortical externa del esqueleto, quizá debido a la inhibición de la actividad osteoclástica. Objetivo: Evaluar los efectos de la microvibración durante 20 minutos a 30 Hz en células osteoblásticas y osteoclásticas para determinar la expresión de IL-17 y RANKL. Material y métodos: Osteoblastos derivados del cráneo del ratón Balb/C fueron sembrados en cajas de 24 pozos de 1.5 cm (Gybco, EUA) en un medio de cultivo DMEM F-12 (ATCC, EUA) y osteoclastos derivados de células madre de la tibia de ratón fueron sembrados en cajas de 24 pozos de 1.5 cm en un medio de cultivo α-MEM (ATCC, EUA), adicionando 0.5 μL/mL de 1α, 25-dihidroxivitamina D3 (Sigma-Aldrich, EUA). Ambos medios de cultivo fueron suplementados con 10% de suero fetal bovino (Gybco, EUA), 1% de antibióticos y antimicóticos, en una incubadora de tejidos (NuAire, EUA) a una atmósfera de 5% de CO2 y 95% de airea una temperatura de 37 o C. Posteriormente, las células cultivadas se sometieron a microvibraciones (0.25 N; 30 Hz) con el aparato AcceleDent (Ortho Accel, EUA) durante 20 minutos. Antes y después de las microvibraciones se recolectaron 500 μL de sobrenadante de las células, el cual fue almacenado en un ultracongelador a -70 oC (Thermo, EUA) para posteriormente determinar la expresión de IL -17 y RANKL (Peprotech, Rocky Hill, NJ, EUA) por medio del ensayo de ELISA. Resultados: La microvibración mostró una sobrerregulación estadísticamente significativa en la alteración de IL-17 tanto en los cultivos de osteoblastos como el de los osteoclastos comparada con el grupo control. Sin embargo, en los osteoclastos y osteoblastos hubo una bajorregulación estadísticamente significativa de la expresión de RANKL comparada con el grupo control. Conclusión: El estudio demostró que tanto osteoblastos como osteoclastos cultivados in vitro sometidos a microvibración de 30 Hz durante 20 minutos producen factores solubles relacionados con la maduración e inhibición osteoclástica
Las obligaciones fiscales del odontólogo
Authors: Tiol-Carrillo Agustín
Published: August 2022

De conformidad con la Constitución, todos los mexicanos tienen la obligación de asistir al gasto público a través del pago de impuestos, de forma proporcional y equitativa a los ingresos de cada individuo según su actividad profesional. Los odontólogos tienen una actividad profesional muy específica que los obliga a cumplir puntualmente con sus obligaciones fiscales, como el registro ante el Servicio de Atención Tributaria, expedición de recibos de honorarios, declaraciones y deducciones fiscales. El objetivo de este artículo consiste en citar las obligaciones fiscales que los odontólogos tienen en su actividad profesional, la forma correcta de hacerlo y mencionar las sanciones que existen en caso de evasión fiscal en México.
Tratamiento de corrección clase II con extracciones de segundos molares superiores: reporte de caso clínico
Authors: Sánchez Ochoa Florencia , Mejía Ávalos Tania Elizabeth , Rodríguez-Chávez Jacqueline Adelina , Villanueva Betancourt Daniel , Covarrubias Guitrón Mónica
Published: August 2022

Introducción: En algunas ocasiones, las extracciones de premolares no son suficientes para corregir el apiñamiento severo, el excesivo overjet, la clase II molar y el perfil protrusivo, por lo que se sugieren las extracciones de los primeros o segundos molares, siempre y cuando observemos la presencia de los terceros molares con anatomía y condiciones adecuadas. Objetivos: Corrección de la clase II y el apiñamiento severo, por medio de extracciones de los cuatro primeros premolares, y de los segundos molares superiores. Reporte de caso: Paciente masculino de 14 años de edad, con base en el análisis de sus estudios esqueletales, dentales y de tejidos blandos se diagnosticó una clase II esqueletal por protrusión maxilar y retrusión mandibular, con un patrón de crecimiento vertical. Se realizaron extracciones de los primeros premolares superiores e inferiores, con el objetivo de liberar el apiñamiento. Además, se extrajeron los segundos molares superiores, para facilitar la distalización de los primeros molares superiores y obtener espacio extra para la corrección de la sobremordida horizontal. Se colocaron brackets MBT slot 0.22”, siguiendo la secuencia del tratamiento ortodóncico. Resultados: Con el tratamiento se mantuvo el perfil de manera estable y dentalmente se obtuvo la clase I canina y molar. Se consiguió una correcta sobremordida vertical y horizontal, así como líneas medias centradas. Se establecieron las guías anterior y canina, y se logró liberar el apiñamiento. Conclusiones: Las extracciones de molares, ya sean primeros o segundos, son una alternativa en casos de clase II con apiñamiento severo, perfil protrusivo y overjet excesivo, siempre y cuando se lleve un control del caso y se mantenga el monitoreo constante de los terceros molares.
Face Recognition Based Automated Student Attendance System
Authors: Geetha K. , Sreerambabu Dr. J. , Santhosh N.
Published: August 2022

Abstract: The Oxford Dictionary defines a face because the a part of a man or woman's head from the brow to the chin. In human interactions, the face is the maximum giant issue as it incorporates vital facts approximately an person. All people will well known human beings from their faces. The proposed answer is to broaden an running prototype of a gadget that could facilitate elegance attendance control for the academics withinside the school rooms through detecting the faces of students from an photograph taken in a school room. The database can shop the faces of students, as soon as the face of the person fits with one in all of the faces held withinside the database then the attendance is recorded. In latest years, evaluation has been allotted and face reputation and detection structures are advanced. A wide variety of those are used on social media structures like Facebook, Banking apps, authorities offices, etc. In today’s aggressive world, with very much less school room time and growing operating hours, teachers can also additionally want equipment that may assist them to manipulate treasured elegance hours efficiently. Instead of that specialize in teaching, teachers are caught with finishing a few formal duties, like taking attendance, keeping the attendance document of every scholar, etc. Manual attendance marking unnecessarily consumes school room time, while clever attendance via face reputation strategies enables in saving the school room time of the lecturer. Attendance marking via face reputation may be implied with inside the school room through shooting the photograph of the scholars with inside the school room thru the digital digicam installed.
KEANEKARAGAMAN MAKROFAUNA TANAH DI KAWASAN PERKEBUNAN COKLAT (Theobroma cacao L. ) SEBAGAI BIOINDIKATOR KESUBURAN TANAH DAN SUMBER BELAJAR BIOLOGI
Authors: Nurrohman Endrik , Rahardjanto Abdulkadir , Wahyuni Sri
Published: August 2022

ABSTRAKJenis penelitian yang digunakan adalah penelitian deskriptif kuantitatif. Penelitian ini dilakukan pada tanggal 20-28 Maret 2015 dengan metode jebakan (Pit tfall Trap). Penelitian dilakuka  bertujuan untuk mengetahui jenis makrofauna tanah, parameter ekologi, indeks keanekaragaman jenis, dan indeks kemerataan jenis yang terdapat di kawasan perkebunan coklat. Hasil penelitian menunjukkan bahwa makrofauna tanah yang ditemukan terdiri dari jenis Tachita angulata, Cryptocercus garciai, Lymnaea rubiginosa, Odontoponera denticulata, Sigmoria trimaculata, Pirata piratichus, Sitena sp., Grillus sp., Scolopendra gigantea, Forficula auricularia, Hydrochara soror, Leptocarisa acuta, Trigoniulus corallinus, Odontomanchus sp., Lumbricus rubellus, Phyllopaga sp., Componatus arogans, Geophilus sp., Gryllotalpa grillotalpa, Ploiaria sp.. Parameter ekologi makrofauna tanah adalah: (1) Kepadatan berkisar antara 0,25 ind/m2 – 4,75 ind/m2, kepadatan relatif berkisar antara 0,002 - 0,052. kepadatan terendah jenis Grillotalpa grillotalpa dan tertinggi jenis Pirata piraticus (2) Frekuensi berkisar antara 0,16 – 1,00, frekuensi relatif berkisar antara 0,018 – 0,115 dengan nilai frekuensi terendah jenis Grillotalpa grillotalpa dan tertinggi jenis Scolopendra gigantea. (3) Indeks nilai penting tertinggi jenis Pirata piratichus  5,28, terendah Grillotalpa grillotalpa 0,027. Indeks keanekaragaman jenis Shannon wiener (H’) kategori keanekaragaman jenis rendah. Nilai evennes (E) populasi cenderung merata. Hail Uji C-Organik tanah sangat tinggi berarti tanah tergolong tanah yang subur. Rendahnya keanekaragaman karena adanya penggunaan pestisida jenis Carbokfuran yang mendominasi. Hasil penelitian ini digunakan sebagai sumber belajar biologi berupa buku petunjuk praktikum.Kata kunci: Makrofauna Tanah, Bioindikator dan Keanekaragaman
PENERAPAN PEMBELAJARAN GUIDED INQUIRY UNTUK MENINGKATKAN MOTIVASI DAN HASIL BELAJAR IPA PADA SISWA KELAS VIII- A SMP MUHAMMADIYAH 2 BATU
Authors: Ratnaningrum Dyah Ayu , Chamisijatin Lise , Widodo Nur
Published: August 2022

ABSTRAKGuided inquiry atau inkuiri terbimbing adalah salah satu pembelajaran inkuiri yang dalam pelaksanaannya guru menyediakan bimbingan atau petunjuk cukup luas kepada siswa. Sebagaian perencaannya dibuat oleh guru, siswa tidak merumuskan problem atau masalah. Permasalahan yang dihadapi adalah semangat siswa masih kurang ketika proses pembelajaran berlangsung, kurangnya keinginan dan keberanian bertanya ketika ada permasalahan terhadap materi yang akan disampaikan. Tujuan penelitian ini adalah untuk (1) Mendeskripsikan penerapan pembelajaran Guided Inquiry untuk meningkatkan motivasi dan hasil belajar IPA pada siswa kelas VIII-A SMP Muhammadiyah 2 Batu  (2) Mendeskripsikan peningkatan motivasi pada siswa kelas VIII-A Muhammadiyah 2 Batu (3) Mendeskripsikan peningkatan hasil belajar IPA pada siswa kelas VIII-A SMP Muhammadiyah 2 Batu.Jenis penelitian ini merupakan penelitian tindakan kelas (PTK). Penelitian ini dilaksanakan dalam dua siklus. Tempat dan waktu penelitian dilaksanakan pada tanggal 25 Nopember- 12 Desember 2013 di SMP Muhammadiyah 2 Batu. Sasaran dalam  penelitian ini adalah siswa kelas VIII-A yang berjumlah 21 siswa. Metode pengumpulan data menggunakan lembar observasi, tes dan hasil belajar, sedangkan motivasi belajar siswa dianalisis menggunakan teori ARCS yang terdiri dari 4 aspek  Attention (perhatian),  Relevance (keterkaitan), Self condition (kepercayaan diri), Satisfaction (kepuasan). Hasil belajar dianalisis dengan menggunakan ketuntasan belajar. Ketuntasan belajar masing-masing siswa disesuaikan dengan KKM sekolah yaitu 75.Hasil penelitian pada siklus I menunjukkan persentase rata-rata dari hasil belajar siswa yang meliputi penyajian masalah, membuat hipotesis, melakukan percobaan, menjelaskan hasil data, membuat kesimpulan adalah 70,26%. Setelah dilakukan perbaikan tindakan siklus II rata-rata dari hasil belajar siswa 80,72%. Jadi meningkat sebesar 10,46%. Berdasarkan angket motivasi, dari siklus I ke siklus II terdapat peningkatan pada aspek attention sebesar 10,78%, relevance 13,09%, self condition 7,13% dan satisfaction meningkat sebesar 12,41%. Kata Kunci: Pembelajaran Guided Inquiry, Motivasi, Hasil Belajar.
Environmental education research in Indonesian Scopus indexed journal: A systematic literature review
Authors: Husamah H. , Suwono Hadi , Nur Hadi , Dharmawan Agus
Published: August 2022

Studies in the field of environmental education need to be continuously promoted in line with the increasing number of environmental problems. The purpose of this systematic literature review (SLR) was to review and compare investigations of researches on articles published by one Indonesian Scopus Indexed journal i.e., Jurnal Pendidikan IPA Indoneia (JPII) so that they are expected to have significant contributions to the topic of environmental education. This systematic literature review adopts five-step guidelines. The study standards that meet the requirements were as follows: (1). The data used were from the 2012-2021 publication year; (2) articles published in English; (3) Full paper can be accessed; (4) related to the theme of environmental education.  It can be concluded that JPII is a pro-environment education journal. JPII publishes 26 articles related to the theme of environment education. The most frequently used keywords were environmental education and students. JPII's important contribution in the theme of environmental education is to provide a real example of the implementation of SETS and to emphasize that the success of implementing environmental education depends on the models, methods, techniques, and tools that are continuously developed by experts.
Epidemiologic features according to age groups of pediatric dental injury in emergency departments
Authors: Kim Seon Woo , Choi Jea Yeon , Cho Jin Seong , Woo Jae-Hyug , Jang Jae Ho , Choi Woo Sung , Hyun Sung Youl
Published: August 2022

Purpose: The aim of this study was to investigate the epidemiologic features of pediatric dental injury according to age groups using Korean national data.Methods: We reviewed the data from 2015 to 2019 Emergency Department-based Injury In-depth Surveillance registry, which involves 23 emergency departments in Korea. We included children aged 18 years or younger with the International Classification of Disease, 10th Revision codes related to dental injury. Other or combined codes were excluded. The children were classified by age groups: infants (< 1 year), preschoolers (2-6), schoolers (7-12), and adolescents (13-18). As per the age groups, we compared the clinical characteristics, injury event profiles, and outcomes. Results: The study population (n = 33,020) consisted of 8,900 infants (27.0%), 15,705 preschoolers (47.6%), 5,295 schoolers (16.0%), and 3,120 adolescents (9.4%). Their median age was 3 years (interquartile range, 1-7), and boys accounted for 64.2%. The most common mechanism, type of activity, and place were slip down (14,274 [43.2%]), daily activity (23,777 [72.0%]), and home (19,980 [60.5%]), respectively. Among the injury types, soft tissue injury was most common (24,357 [73.8%]). As for the outcomes, 32,841 (99.5%) children were discharged, and 332 (1.0%) children had severe injury. As the age increased, the frequencies changed as follows. As for the place and type, household injury and soft tissue injury decreased while outdoor injury, such as road traffic injury, and tooth fracture increased (P < 0.001). As for the type of activity, injuries related to exercise/sports and education increased (P < 0.001). Of the sports activity, ball sports increased while kickboard/cycle decreased (P < 0.001).Conclusion: Using the epidemiologic features of pediatric dental injury, it is advisable to establish injury prevention strategies according to the age groups.
The impact of renewable energy generation on productivity in selected developing countries
Authors: Cheuka Pamelah , Choga Ireen
Published: August 2022

This study is an empirical analysis of the impact of renewable energy generation on productivity in seven countries in the South African Development Community (SADC). The study operationalizes the alternative hypothesis that renewable energy generation exerts an impact on productivity in the SADC from 1990 to 2019. The study contributes to the literature by employing renewable energy generation as the independent variable, and not renewable energy consumption, which is the case in most studies. The empirical analysis was employed using the panel autoregressive distributed lag (ADRL) model (da Silva, Cerqueira, & Ogbe, 2018). It was established that renewable energy generation had a significant and positive impact on productivity, as measured by gross domestic product (GDP), over the long term. Countries should implement policies aimed at increasing electricity generation from renewable energy sources in order to meet the growing demand for electricity. Infrastructure development, skills training, technical support, and a Just Energy Transition should be the primary emphasis of policy initiatives.
Bilateral Cleft Lip and Unilateral Cleft Palate with Unilateral Renal Agenesis: A Case Report
Authors: Kumar Abhishek , Shah Siddhartha , Khadka Sanchita , Birajee Gajendra , Shah Lokraj , Koirala Bandana
Published: August 2022

Cleft lip and palate (CLP) are one of the most frequently
occurring craniofacial congenital anomalies. A syndromic association is
frequently seen in such cases. A feeding obturator is a prosthetic aid
that assists a patient in obturating a cleft until surgery is performed.
Cleft lip surgery or cheiloplasty is often performed three months after
birth, while palate surgery or palatoplasty is typically performed
between the ages of six and fourteen months. A 2-day-old
newborn presented to the Pediatric Emergency with a complaint of
difficulty in feeding. On examination, bilateral cleft of the lip and
unilateral cleft of the palate was present. The ultrasonography of the
fetus before the birth had revealed non-visualized left kidney, so an
ultrasonography (USG) of the abdomen and pelvis was advised which
confirmed the finding i.e., left renal agenesis. Electrocardiography
(ECG) revealed an arterial septal defect (ASD) of 4.5
mm. Such presentation is commonly seen in cases of isolated
gonadotropin-releasing hormone (GnRH) deficiency (IGD). A custom-made
feeding obturator was fabricated and delivered to help the baby overcome
feeding difficulties. Parents were instructed and well-taught to feed
the child with the appliance in place. Apart from giving appropriate
instructions regarding feeding and maintenance of the appliance, parents
were also informed about the surgical procedures that would be followed
at a later date. Also, considering the exceptional psychological
situation of the family and the need for a long-standing relationship
between the cleft team for a successful outcome, appropriate
counseling with reassurance was rendered to the family members.
Multi Attribute Monitoring Method for Process Development of Engineered Antibody for Site-Specific Conjugation
Authors: Hines Alistair R. , Edgeworth Matthew J. , Devine Paul W. A. , Shepherd Samuel , Chatterton Nicholas P. , Turner Claire , Lilley Kathryn S. , Chen Xiaoyu , Bond Nicholas J.
Published: August 2022

Antibody drug conjugates are a class of biotherapeutic proteins which
have been extensively developed in recent years resulting in new
approvals and improved standard of care for cancer patients. Among the
numerous strategies of conjugating cytotoxic payloads to monoclonal
antibodies, insertion of a cysteine residue at position 239 (C239i)
achieves a tightly controlled, site specific drug to antibody ratio.
Tailored analytical tools are required to direct the development of
processes capable of manufacturing novel antibody scaffolds with the
desired product quality. Here, we describe the development of a high
throughput, 12-minute, mass spectrometry based method capable of
monitoring four distinct quality attributes simultaneously: variations
in the thiol state of the inserted cysteines, N-linked glycosylation,
reduction of inter-chain disulphide bonds, and polypeptide
fragmentation. When deployed, the method provided new insight into the
properties of C239i antibody intermediate and its manufacturing
processes. First, C239i forms exclusively oxidised thiol states within
the bioreactor, of which a variant containing an additional disulphide
bond was invariably produced and remained relatively constant throughout
the fed-batch process; reduced thiol variants were introduced upon
harvest. Second, close to twenty percent of N-linked glycans contained
sialic acid, substantially higher than anticipated for wildtype IgG1.
Lastly, previously unreported polypeptide fragmentation sites were
identified in the C239i constant (C 2) domain and the
relationship between fragmentation and glycoform explored. This work
illustrates the utility of applying a high-throughput liquid
chromatography mass spectrometry (LC-MS) multi-attribute monitoring
method to support the development of engineered antibody scaffolds.
A 1.2V High-speed Low-power Preamplifier Latch based Comparator
Authors: He Yue feng , Yuan Guo shun
Published: August 2022

The power consumption of chips has emerged as a major concern with the
increased integration of analog circuitry. This work focuses on a
two-stage comparator based on a preamplifier with latch for successive
approximation analog-to-digital converter. In order to minimize power
loss and delay time, the charge steering approach was used in the design
of latch as well as preamplifier. The suggested comparator is simulated
in SMIC 0.18um process in comparison to the comparator without charge
steering mode. The results reveal that the average power consumption is
only around 22uW for varied input voltage at a supply voltage of 1.2V,
which is relatively lowered by approximately 30%. Meanwhile, delay time
is also reduced by about 25%.
The Effects of Client Machiavellian Traits and Fraud Motivation on Fraud Risk Assessments
Authors: Losi Heather J. , Giambatista Robert C. , Boyle Douglas M.
Published: August 2022

The extant fraud literature indicates the Dark Triad personality trait of Machiavellianism can indicate behavioral warning signs, signal the motivation of a potential fraudster, and be used in a predictive approach to fraud assessments (Brody, Melendy, and Perri 2012; Hermanson, Justice, Ramamoorti, and Riley 2017). In a 2 × 2 experiment, this study examines the effects of client manager Machiavellian traits and fraud motivation on fraud risk assessments. We find that participants' fraud risk assessments are higher when client traits are consistent with high Machiavellianism. We did not find a significant fraud motivation effect. The results indicate evidence of additional attitude/rationalization risk factors for consideration under the fraud triangle and the effects on judgment when assessing fraud risk. We provide insights on the ability of auditors to recognize high/low pressure/motivation situations within the context of a case study. Finally, the study provides evidence for documentation in consideration of fraud factors.
YES Bank Fraud: Examining the Softer Underbelly of the Fraud from a Behavioral Model
Authors: Sharma Nistala Jagannath , Aggarwal Divya
Published: August 2022

Poor corporate governance, insufficient regulatory supervision, and lack of compliance are susceptible factors for fraudulent activities in the Indian banking sector. This study examines the role of softer aspects like the CEO's personality traits that instigate an organization's involvement in fraudulent activities. Our study proposes a conceptual model to examine the behavioral fabric of fraud by widening the scope of the existing corporate fraud models. The conceptual model is built upon three primary components: dark personality traits of the CEO leading to CEO hubris, internal firm factors, and external firm factors. The proposed model aims to analyze the massive fraud done at YES Bank, considered a pioneer for the Indian private banking sector. The study aims to contribute toward existing fraud theory literature by proposing a new model. It aims to contribute to the increasing sensitivity of forensic accountants toward examining the psychological and behavioral traits of a fraudster.
An Examination of and a Commentary on the Increased Length of Published Research Papers
Authors: Nigrini Mark J.
Published: August 2022

The page lengths of the articles in the top accounting journals have been steadily increasing over the past two decades. The increase is about 42 percent using the average page length, and 45 percent using the median page length.These length increases are understated because the more recent articles now include online supplementary materials that are not counted as published pages. The number of authors per article has also increased over the past two decades from 2.1 authors to an average of 2.8 authors per article. To reduce the level of editors', reviewers', and our colleagues in the academe's fatigue, journal editors should consider word length constraints. Also, making our research more appealing to accounting professionals, policymakers, and the public is another incentive for journal editors to consider word length constraints.

Data Availability: The data are available from the author on request.

JEL Classifications: M21; M40.
What If Borrowers Were Informed about Credit Reporting? Two Natural Field Experiments
Authors: Liao Li , Martin Xiumin , Wang Ni , Wang Zhengwei , Yang Jun
Published: August 2022

Using two natural field experiments, we examine how warning individual retail borrowers that their loan performance will be reported to a public credit registry before and after the loan take-up affects their borrowing behavior. We show that credit warnings reduce default rates by 3.7 to 7 percentage points and increase loan take-up rates by 4.1 percentage points, which suggests that credit warnings benefit both lenders and borrowers. The main drivers appear to be borrowers’ anticipation of a reduction in lenders’ informational rents and improved repayment incentives. Moreover, the reduction in default rates is comparable for borrowers who receive the credit warning before and after the loan take-up. As credit warnings received before but not after a loan take-up can affect the borrower pool, and thus the overall credit risk of the pool, the results suggest that credit warnings have little net effect on the pool’s credit risk due to selection.

JEL Classifications: G10; G21; G23.
Association of Estimated Time-in-Range Capillary Glucose Levels Versus HbA1c With Progression of Microvascular Complications in the Diabetes Control and Complications Trial
Authors: Lachin John M. , Bebu Ionut , Gao Xiaoyu , Nathan David M. , Zinman Bernard ,   the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group
Published: August 2022

OBJECTIVE

Estimated time in range (eTIR) obtained from DCCT glucose profiles (pre- and postprandial and bedtime) was recently reported to be associated with microvascular outcomes and was recommended as a clinical trial outcome, but without consideration of HbA1c.

RESEARCH DESIGN AND METHODS

The associations of eTIR with diabetic retinopathy and microalbuminuria were assessed without and with adjustment for HbA1c and baseline covariates.

RESULTS

Adjusted for HbA1c and covariates, eTIR was marginally significantly associated with retinopathy in the full cohort (hazard ratio [HR] 1.12 per 10% lower eTIR [95% CI 1.0, 1.26], P = 0.042). Conversely, HbA1c was significantly associated with both outcomes (HR ≥1.19 per 0.5% higher HbA1c, P ≤ 0.0002) in five of six adjusted analyses.

CONCLUSIONS

The association of eTIR with complications is largely explained by its correlation with HbA1c. HbA1c, not eTIR or continuous glucose monitoring TIR, remains the preferred outcome in clinical studies of type 1 diabetes complications.
Equity in the Provision of Diabetes Self-Management Education and Support
Authors: Blanchette Julia E. , Aaron Siobhan P. , Allen Nancy A. , Litchman Michelle L.
Published: August 2022

Diabetes self-management education and support (DSMES) interventions must be accessible to all people with diabetes. To address equity in the delivery of DSMES, interventions should consider the unique needs of various populations. This article outlines the needs of a wide range of populations, including people with diabetes who are racially or ethnically diverse; have limited English proficiency or literacy; are deaf or hard of hearing; are blind or have low vision; are neurodiverse; live with learning disabilities or intellectual or developmental disabilities; have dementia or cognitive impairment; or are of sexual and/or gender minority. The authors discuss how best to tailor DSMES to meet the needs of these diverse groups.
Müller Pál badeni Decapoda-gyűjteménye a Magyar Természettudományi Múzeumban
Authors: Dulai Alfréd , Hyžný Matúš
Published: August 2022

A Középső-Paratethys üledékei elterjedtek Magyarországon, leggyakrabban a badeni (15,97–12,6 millió évvel ezelőtti) üledékekkel találkozhatunk. Az akkori sekélytengeri környezetek nagyon változatos élővilágnak nyújtottak otthont, köztük a tízlábú rákoknak, melyek maradványai gyakran megtalálhatók a badeni rétegeket feltáró lelőhelyeken. Magyarország régóta fontos szerepet játszik a kainozoós Decapoda kutatásban, elsősorban Lőrenthey Imre és Müller Pál gyűjteményének és kutatásának köszönhetően. Müller Pál rendkívül gazdag Decapoda gyűjteménye a 2015-ben bekövetkezett halála után akaratának megfelelően a Magyar Természettudományi Múzeumba került. Anyagának legjelentősebb részét a magyarországi badeni rétegekből gyűjtötte, és a példányok nagyrészt Budapestről, vagy Budapest környékéről származnak (Tétényi-fennsík, Diósd, Biatorbágy, Budafok, Rákos, Keresztúri út, Örs vezér tere, Kerepesi út, Gyakorló út, Thököly út, Mező Imre út = Fiumei út, Telepy utca). A Visegrádhegységből (Visegrád), a Börzsönyből (Nagymaros Törökmező, Zebegény, és Szob), és a Cserhátból (Mátraverebély, Szentkút és Sámsonháza) származó anyagok szintén jelentősek. A dunántúli badeni lelőhelyekről (Nyírád, Balatonakali-40, Kishajmás, Fertőrákos-21) viszont eddig nagyon kevés tízlábú rák maradványa került elő. Az eddigi vizsgálatok alapján csaknem száz Decapoda fajt lehetett elkülöníteni a magyarországi badeniben, a Gebiidea (1 faj), Axiidea (9 faj), Anomura (20 faj), és Brachyura (69 faj) alrendek képviselőiből. A fajok mindegyikét részletesen feldolgoztuk a közelmúltban megjelent monográfiában, revideált leírásokkal, elterjedési adatokkal, valamint fényképes ábrázolásokkal, különös tekintettel a típuspéldányokra. A 99 Decapodafaj rendszertani áttekintése mellett részletesen ismertettük azokat a magyarországi lelőhelyeket, ahol badeni tízlábú rák maradványok kerültek elő. A rendszertani leírások mellett határozókulcsot készítettünk valamennyi előkerült fajhoz (különkülön a carapax és az olló maradványokra). A taxonómiai vizsgálatok során az eddigitől eltérő genushoz soroltunk tíz fajt (új kombinációk), és számos faj esetében megállapítottuk, hogy azok megegyeznek korábban leírt fajokkal (szinonímák).
Opettajaopiskelijoiden kielitoinen toimijuus monikielisten oppijoiden etäohjauksessa
Authors: Aalto Eija , Skinnari Kristiina , Mård-Miettinen Karita , Siponkoski Milka
Published: August 2022

Artikkelissa tarkastellaan opettajaopiskelijoiden kielitietoista toimijuutta ohjaustilanteessa, jossa he tukevat etäyhteyksin eri-ikäisiä monikielisiä oppijoita. Ennestään tuntemattomien monikielisten oppijoiden ohjaaminen etäyhteyksin oli opettajaopiskelijoille uusi ja haastava tilanne pandemiakriisissä vuonna 2020. Tutkimuksen aineistona on yhdentoista opettajaopiskelijan ohjaustehtävästä kirjoittamat raportit, jotka on analysoitu aineistolähtöisen temaattisen analyysin keinoin. Analyysissa tarkasteltiin seikkoja, jotka mahdollistavat ja rajoittavat varhaiskasvatuksen, luokanopettajakoulutuksen ja kielten aineenopettajakoulutuksen opiskelijoiden kielitietoista toimijuutta monikielisten oppijoiden etäohjaustilanteissa. Tulokset osoittavat, että opettajaopiskelijoiden kielitietoinen toimijuus vaihteli sekä yksilöllisesti että tilanteisesti ohjausprosessin aikana. Osalla opettajaopiskelijoista toimijuus kasvoi, kun he aktiivisesti ratkoivat kohtaamiaan ongelmia. Osa koki haasteet suuriksi eikä löytänyt niihin ratkaisuja, mikä heikensi heidän toimijuuttaan. Yhteiskunnallisesti haasteellisessa tilanteessa opettajankoulutuksen kontribuutio aitojen ongelmien ratkaisemiseen koettiin tärkeäksi.
 
Teacher students' Language Aware Agency in distance tutoring of multilingual learners
Abstract
This article addresses teacher students' Language Aware Agency in the new and challenging situation of guiding multilingual learners of different ages in distance in the 2020 pandemic situation. The data of the study consist of the learning diaries and reports by eleven teacher students on their online tutoring experiences and were analysed by Thematical Content Analysis. The analysis focused on the elements that either enhanced or restricted the agency of teacher students. The results show that their agency varied both individually and situationally throughout the guidance process. The agency of some teacher students strengthened as they actively solved the encountered problems. Conversely, for other teacher students the challenges were overwhelming, diminishing their agency. In a societally demanding situation, the contribution of teacher education to authentic community issues was seen important.
Keywords: teacher education, language aware agency, multilingual learner, online tutoring
Optimizing to Minimize Thrust Force in Drilling Carbon Fiber Reinforced Plastic Composites with HSS Drill Bit Using Taguchi-Pareto Particle Swarm Optimization Method
Authors: Taiwo Emmanuel Oluwatobi , Oke Sunday Ayoola
Published: August 2022

In this study, a robust method of Taguchi-Pareto (TP) coupled with particle swarm optimization (PSO) is proposed to minimize the thrust force in the drilling of carbon fiber reinforced plastic composites. Taguchi-Pareto is used against Taguchi (T) to emphasize the prioritization scheme essential for deploying the resources to parameters. Besides, and differently from earlier studies, particle swarm optimization is integrated with the Taguchi-Pareto to optimize the structure further. A further result is placed in the fitness function of the PSO to cultivate the velocity and position vectors. In the TP-PSO, the Pareto scheme is introduced to prioritize the factors based on the 80-20-rule. The Taguchi method yielded a feasible optimal parametric setting. The TPSO and TPPSO attained minimum thrust force in four and seven iterations, respectively. Furthermore, the PSO, TPPSO, and TPSO hold the first, second, and third positions, respectively. Results suggest that the proposed robust TPPSO offers an important indicator of optimization of the thrust force while drilling carbon fiber reinforced plastic composites using existing datasets. The usefulness of this effort is to help drilling operators and process engineers undertake energy-saving decisions.
Analysis of the effectiveness of some macroeconomic variables on the industrial sector in Iraq for the period (2004-2020)
Authors: Hamid Munther Alawi , Saleh Lawrence Yahiya
Published: August 2022

The research aims to clarify the nature of the relationship between some macroeconomic variables represented (public spending, interest rate, exchange rate) and the industrial sector in Iraq for the period (2004-2020), which expresses the content of the Iraqi economy, and the use of standard analysis tools to know the impact of some macro variables (expenditure year, interest rate, exchange rate) on the industrial sector in Iraq for the duration of the study. The research reached to prove the validity of the hypothesis that some macroeconomic variables did not play a positive role in the Iraqi industrial sector for the period 2004-2020. where it was concluded through the results to a clear decline in its contribution to the output, as it did not exceed (3%) and with an average period of (2.3%) during the study, due to the weakness of production lines and the high level of costs as a result of obsolescence and loss of equipment in addition to the looting that this sector was subjected to. Accordingly the oil surpluses achieved each year and directing the development of economic growth and covering local manufacturing from imported raw materials or through the modernization of manufacturing methods and the use of technology capable of increasing production and reducing costs.
Correlation consistent auxiliary basis sets in density fitting Hartree-Fock. The atoms sodium through argon revisited.
Authors: Nash Harry , Shaw Robert , Hill Grant
Published: August 2022

We present a series of auxiliary basis sets, for the elements Na to Ar, for use in density-fitted Hartree-Fock calculations with the correlation consistent cc-pV(n+d)Z orbital basis sets. Benchmarking on total molecular energies, reaction energies and the spectroscopic constants of the SO molecule demonstrate that the new sets address the deficiencies of using existing auxiliary sets in combination with these orbital basis sets. We also report auxiliary basis sets for Na and Mg matched to cc-pVnZ, along with recommendations for pairing auxiliary basis sets to the cc-pVnZ-F12 basis sets for Hartree-Fock calculations.
Progress Towards the Syntheses of Bactobolin A and C4-epi-Bactobolin A Using a Sulfamate-Tethered Aza-Wacker Cyclization Strategy
Authors: SATHYAMOORTHI SHYAM , Nagamalla Someshwar , Mague Joel
Published: August 2022

We present a progress report towards Bactobolin A and C4-epi-Bactobolin A. Sulfamate-tethered aza-Wacker cyclization followed by a Tsuji-Wacker ketone synthesis furnishes a key tricyclic intermediate which we hypothesize can be elaborated into C4-epi-Bactobolin A. Epimerization of one of the stereocenters of this compound furnishes an intermediate which we hypothesize can be elaborated into Bactobolin A.
Systematic exploration of privileged warheads for covalent kinase drug discovery
Authors: Zhao Zheng , Bourne Philip E.
Published: August 2022

Kinase-targeted drug discovery for cancer therapy has advanced significantly in the last three decades. Currently, diverse kinase inhibitors or degraders have been reported, such as allosteric inhibitors, covalent inhibitors, macrocyclic inhibitors, and PROTAC degraders. Out of these, covalent kinase inhibitors (CKIs) have been attracting attention due to their enhanced selectivity and exceptionally strong affinity. Eight covalent kinase drugs have been FDA approved thus far. Here, we review current developments in CKIs. We explore the characteristics of the CKIs: the features of nucleophilic amino acids and the preferences of electrophilic warheads. We provide systematic insights into privileged warheads for repurposing to other kinase targets. Finally, we discuss trends in CKI development across the whole proteome.
Material Descriptors to Predict Thermoelectric Performance of Narrow-gap Semiconductors and Semimetals
Authors: Toriyama Michael Y. , Carranco Adam N. , Snyder G. Jeffrey , Gorai Prashun
Published: August 2022

Thermoelectric (TE) cooling is an environment-friendly alternative to vapor compression cooling. Narrow-gap semiconductors and semimetals have garnered interest for Peltier cooling, especially following the discovery of Mg3Bi2-based materials. New TE materials with high coefficients of performance are needed to further advance this technology. Computations have enabled the discovery and design of new TE materials. Large-scale computational searches often rely on material descriptors, which are based on the single-band model that does not account for bipolar conduction effects. In this work, we derive three material descriptors to assess the TE performance of narrow-gap semiconductors and semimetals -- band gap, n- and p-type TE quality factors, and an asymmetry parameter. These computationally-accessible descriptors are derived from Boltzmann transport theory applied to a two-band model. We show that a large asymmetry parameter is critical to achieving high TE performance through suppression of bipolar conduction. We validate the predictive power of the descriptors by correctly identifying Mg3Bi2 as a high-performing room-temperature TE material. By applying these descriptors to a broader set of 650 Zintl phases, we identify four candidate materials for room-temperature TEs, namely, SrSb2, Zn3As2, NaZnSb, and NaCdSb. The proposed material descriptors will enable fast targeted search of narrow-gap semiconductors and semimetals for low-temperature TEs.
ПСИХОЛОГІЧНІ РЕСУРСИ ОСОБИСТОСТІ В ПОДОЛАННІ ВАЖКИХ ЖИТТЄВИХ СИТУАЦІЙ
Authors: Лящ О. П.
Published: August 2022

Статтю присвячено проблемі психологічних ресурсів, яка активно вивчається в сучасній вітчизняній і зарубіжній психології. Підкреслюється гостра актуальність і значущість дослідження таких ресурсів для теорії та практики. Здійснено аналіз традиційних підходів до проблеми в науці. Представлено теоретичний огляд деяких сучасних концепцій психологічних ресурсів, розглянуто різні дефінітивні позиції щодо психологічної інтерпретації базового поняття. У статті узагальнено філософсько-психологічний зміст поняття психологічних ресурсів та ресурсності особистості. Розглянуто підходи науковців до визначення рівнів і видів психологічних ресурсів особистості. Аналізуються змістовно подібні до явища конструкти, виділені в межах інших психологічних теорій, наприклад «життєвий досвід», «адаптаційний та особистісний потенціал», «резерв», «особистісний капітал», «копінг» тощо. Виявляється психологічна сутність психологічних ресурсів у контексті діяльнісної, адаптаційної, соціально-опосередкованої та інших наукових парадигм. Зазначається інтегративний характер ресурсів як системи індивідуальних властивостей людини, спрямованих на реалізацію функцій життєзабезпечення, системну організацію та взаємодетермінований зв’язок із раціональними, емоційно-почуттєвими, мотиваційно-ціннісними й поведінковими компонентами самосвідомості суб’єкта. Залежно від того, що є предметом дослідження ресурсів, вибираються різні аспекти їх визначення. Проведений аналіз наукової літератури вказує на те, що у вчених немає єдиної позиції щодо розуміння цього поняття. Для успішного подолання важких життєвих ситуацій необхідно розуміти, що стоїть за поняттям ресурсу, тому у викладеному матеріалі розглядаються різноманітні теоретичні підходи до вивчення, а також розкривається специфіка психологічних ресурсів як операційно-дієвих механізмів і можливостей продуктивної самореалізації. Робиться спроба виявлення деяких функціональних ознак феномену, наголошується на його рефлексивному, емоційно-оцінному, смислоутворюючому та регулятивному характері. Окреслено перспективи подальших наукових пошуків.
ПСИХОСЕМАНТИЧНІ ІНДИКАТОРИ ПСИХОЛОГІЧНОГО БЛАГОПОЛУЧЧЯ ЖІНКИ В ПЕРІОД СЕРЕДНЬОЇ ДОРОСЛОСТІ
Authors: Міщиха Л. П. , Коропецька О. М.
Published: August 2022

У статті піддаються дослідженню психосемантичні індикатори психологічного благополуччя жінки у період середньої дорослості. Дається розуміння самого поняття «психологічне благополуччя», яке визначається як інтегральний показник ступеня спрямованості особистості на реалізацію основних компонентів позитивного функціонування, а також реалізованості цієї спрямованості, що суб’єктивно виражається у відчутті щастя, задоволеності собою і власним життям. У дослідженні були виявлені та проаналізовані психосемантичні індикатори психологічного благополуччя жінки в період середньої дорослості. Цьому слугувало використання проективної методики «Незакінчені речення» та техніки метафоризації – застосування психотехнологічних ресурсів метафори. Загальна кількість вибірки склала 30 осіб (жінки вікового періоду середньої дорослості, які проживають в Івано-Франківській, Тернопільській та Рівненській областях). Дослідження проводилось у 2021 році. За результатами дослідження серед основних складових частин психологічного благополуччя, які виокремили респонденти, були: здоров’я (57%); гармонійні стосунки (50%); достаток, хороша робота, матеріальне благополуччя (42%); психологічна рівновага, внутрішній баланс (43%); потреба (та можливості) у самореалізації (30%). Були окреслені чинники, що можуть зруйнувати психологічне благополуччя жінки, серед яких: втрата здоров’я; фінансові труднощі; непорозуміння в родині; життєві потрясіння (війна, смерть близьких, руйнування чи втрата життєво цінного). У процесі виокремлення смислових конструктів з використанням метафори було виявлено, що більшість з них носила життєстверджуючий, позитивний настрій, з мотивацією на активне життя, працю. Значна частина була спрямована на духовну складову частину, що характеризувало зрілу позицію жінок в цьому віці. Разом із тим було виявлено дві модальності емоцій: позитивна і негативна, що є свідченням того, що ставлення до себе, як і до свого життя, є виключно індивідуально-психологічною складовою частиною особистості, де мають місце як особистісні особливості індивідуальності, так і вибудовані ціннісно-смислові конструкти у цей період життя. Окреслені перспективи подальших досліджень, що полягають у віднаходженні ресурсу для підтримки психологічного благополуччя жінок у період середньої дорослості.
Deep Learning Based Gait Recognition Using Convolutional Neural Network in the COVID-19 Pandemic
Authors: Sayeed Md Shohel Shohel , Min Pa Pa , Bari Md Ahsanul
Published: August 2022

Gait recognition is the behavioral biometric trait that tracks humans based on their walking motion. It has gained attention because of its non-invasive and unobtrusive behaviors and applicable to the different application area. In this paper, we target model-free gait recognition with the deep learning approach for the Muslim community in the COVID-19 pandemic. The different convolutional neural network architectures (CNN) are examined by using the spatio-temporal gait representation called Gait Energy Images (GEI). We explored both the identification and verification problems to determine the suitability of the proposed CNN frameworks. In gait recognition, the intraclass variation is larger than the inter-class variation because of the shooting view, the walking speed, the wearing condition, and so on. To tackle this challenge, the verification framework is more suitable for the 1:1 association of gait recognition. As for the verification problem, we implemented the Siamese network with the parallel CNN architecture. All the proposed methods are tested against the public gait datasets called OUISIR-LP and OUISIR-MVLP to determine the identification and verification performance in terms of recognition accuracy and error rate. Doi: 10.28991/ESJ-2022-06-05-012 Full Text: PDF
Productividad del abastecimiento e industrialización maderable en el ejido Aboreachi, Guachochi, Chihuahua
Authors: Rascón-Solano Joel , Aguirre-Calderón Óscar Alberto , Alanís-Rodríguez Eduardo , Jiménez-Pérez Javier , Treviño-Garza Eduardo Javier , Nájera-Luna Juan Abel
Published: August 2022

El objetivo de esta investigación fue evaluar la evolución productiva de una década de abastecimiento, industrialización y comercialización maderable en el ejido Aboreachi, Guachochi, Chihuahua. Se consideraron 10 anualidades de aprovechamiento forestal maderable; de enero del año 2010 a diciembre de 2019 se analizaron 9 327 remisiones de madera en rollo y 2 040 reembarques de madera aserrada. La prueba de Shapiro-Wilks se usó para determinar la normalidad de las observaciones; la homogeneidad de las varianzas se determinó con la prueba de Levene; para evaluar la productividad de las anualidades se realizaron pruebas de Kruskal-Wallis, así como un análisis de correlación de Pearson para evaluar el incremento de los fletes en función del volumen autorizado. En todos los estadísticos se consideró un α=0.05. La extracción forestal con animales de tiro permite aumentar los puestos de trabajo, pero limita la productividad de abastecimiento en conjunto con la calidad de los vehículos. Se obtuvo un incremento en los fletes de madera en rollo y aserrada en relación con el aumento de volumen autorizado (r=0.775 y 0.495, respectivamente). El análisis de Kruskal-Wallis mostró que las diferencias en los flujos de abastecimiento de madera en rollo y egresos de abastecimiento resultaron significativas (α<0.05). Por su parte, el transporte de madera aserrada, egresos de transformación e ingresos por venta presentaron diferencias significativas (α<0.05) entre anualidades. La renovación tecnológica industrial aumentó el rendimiento volumétrico de madera aserrada (9.45 %) y, por consiguiente, la productividad del ejido Aboreachi.
Sanitary update on wheat in Argentina
Authors: Enrique Javier Alberione
Published: August 2022

The wheat production (Triticum aestivum L.) in Argentina is the third in importance after soybeans and corn (source: BCR).