bluuebunny/crossref_metadata_2025 huggingface dataset:
The Dynamic Impact of Taxation on the Economic Growth of Sri Lanka: An ARDL bounds testing approach
Authors: Asel Hettiarachchi , Janaka Fernando , Ananda Rathnayake
Published: December 2022

Discussions on how a government can stimulate an economy through non-distortionary taxation and productive government expenditures have become prominent during the past three decades. Against this backdrop, this paper aims to analyse the short-run and long-run impacts of taxation on the economic growth of Sri Lanka. Some taxes can be distortionary, while others are not. Therefore, while analysing the effect of overall tax level on economic growth, we also estimated the distortionary nature of major tax categories on the economic growth of Sri Lanka. Sri Lanka presents a unique case to analyse the nexus between taxation and economic growth, as the economy was liberalized in 1977. Therefore, the impact of taxation level on economic growth was estimated using a linear Auto-Regressive Distributed Lag (ARDL) model under two scenarios: without controlling for economic liberalization (from 1960 to 2018) and the post-liberalized period (from 1980 to 2018).  The results of both pre-and post-economic liberalization conditions suggest a significant long-run positive impact of tax level on economic growth. Similarly, the impact of consumption tax on short-run economic growth was significant.  In addition, personal and corporate income taxes were non-distortionary, both in the short-run and the long-run, while consumption taxes were non-distortionary in the long-run. This suggests that increasing taxes is a viable policy option in achieving fiscal independence without compromising Sri Lanka's growth potential.

 Keywords: ARDL, Economic Growth, Fiscal policy, Public Sector, Tax Levels, Tax Structure
Green Manufacturing Practices and Sustainable Performance of Organization in Selected Manufacturing Companies in Kegalle District of Sri Lanka
Authors: W.M.M.G.H.K. Walisundara  , N. Thevanes  , A. Anton Arulrajah
Published: December 2022

This study aims to examine the impact of green manufacturing practices on sustainable performance of organization. In order to achieve the study objective, primary data were collected through a questionnaire-based survey among 70 manufacturing companies which are operating in Kegalle district of Sri Lanka. This study has used the convenience sampling (availability sampling) method and the unit of analysis was individual firms. The simple regression analysis was used to test the research model. The findings of the study revealed that there is a moderate level of green manufacturing practices implemented in the selected manufacturing companies and sustainable performance of surveyed companies was recorded at in moderate level. And the findings of the study also suggested that green manufacturing practices have a significant and positive impact on sustainable performance of organization. This study suggested that manufacturing organizations need to focus more on the implementation of green manufacturing practices to ensure organizational sustainability.   

Keywords: Green manufacturing, sustainable performance, Sri Lanka
Determinants of Translating Entrepreneurial Intention to Action: A Study of Undergraduate Students of the University of Peradeniya, Sri Lanka
Authors: D.T. de Alwis  , K.A.S.S. Kodithuwakku  , D. Hemachandra
Published: December 2022

Entrepreneurs are the wealth creators of an economy, and hence business start-ups are always encouraged. Although it is often suggested that entrepreneurial intentions are strong predictors of entrepreneurial action, all intentions do not necessarily translate into action as there is an “intention-action gap” when nascent entrepreneurs fail to act on their intentions. This study aimed to explain the gap between entrepreneurial intentions and entrepreneurial action and identify the determinants of the intention to action translation by surveying the final year undergraduates from different degree programs at a major public university in Sri Lanka. The research focused on the effects of demographic, psychographic, and environmental factors to explain the intention-action gap. Data were collected using a pre-tested self-administered questionnaire. The questionnaire was circulated online among the entire final year undergraduate student population of the University of Peradeniya. Four hundred and fifty-three undergraduate students (n=453) responded to the survey. Hierarchical OLS regression with the main effect model and an interactions model was used for the data analysis. Results found that of the respondents who had entrepreneurial intentions, 32% had taken some actions towards starting a business. The results also revealed a positive relationship between entrepreneurial intention and action and there were positive effects of gender, perceived competence in entrepreneurial skills, entrepreneurial environment in the faculty, and entrepreneurial education on entrepreneurial actions. Furthermore, it was found that progressing from entrepreneurial intention to action was more robust for male undergraduates compared to female undergraduates. Therefore, to promote entrepreneurship, introducing entrepreneurship courses, introducing programmes to improve entrepreneurial skills and competencies and promoting an entrepreneurial culture in the Faculties could be recommended.

Keywords: Entrepreneurial intention, Entrepreneurial action, Hierarchical OLS regression, Students
The Art of Self-Presentation: A Study on Impression Management among Academicians in Sri Lankan State Universities
Authors: Sawani De Silva
Published: December 2022

Impression Management is one of the important phenomena in everyday life, which everyone uses as a strategy to improve their current state of affairs. This qualitative study on impression management among academicians in Sri Lankan state universities was carried out to explore the impression management strategies which are adopted by academicians, while trying to identify the motives behind them to practice those strategies. Eight academics of a leading faculty in a state university, which is in the Colombo district were selected as the sample using the purposive sampling technique. Semi-structured interviews were adopted to collect data and the Thematic Analysis Technique was used to analyze those collected data. Findings of the study indicate that academicians of the selected context use a variety of impression management strategies. Those include direct strategies of creating a good image through presenting the self as competent, likable, diligent, supplicatory, and dangerous. Strategies of apology, reasoning and rejecting were identified as the direct ways of defending a bad image. Indirect impression formation is done by criticizing, passing the fault to others, and getting appreciation from others. Not only that, but academicians also use non-verbal ways such as attire, facial expressions, and vehicle & other accessories to create impressions. Further, the results illustrate that academicians are motivated to manage impressions to maintain a good image of themselves, to build a relationship, to achieve job-related goals such as, job security, career growth, and finally to motivate others for success. This study also provides some valuable theoretical and managerial implications and considerations for future research in the field of impression management.

Keywords: Academicians, Impression Management, Impression Management Strategies, Impression Management Motives
Is Political Instability an Obstacle to Economic growth? Evidence from South Asia
Authors: Ananda Rathnayake
Published: December 2022

The nexus existing between the growth rate of countries and political instability has been subjected to increasing interest among academic scholars and policymakers in different contexts all around the globe. The current study examined the relationship between political instability and economic growth in both  short and long-run, employing the Panel Auto Regressive Distributed Lag (PARDL) model. Through the efforts taken via the study to redefine the political instability and growth nexus in South Asia, it could be stated that despite the insignificant impact of political instability on economic growth in the short run, countries gain the capability in elevating the growth level by maintaining stable political regimes in the long run. The results suggested that there is an overall negative and also a significant linkage between political instability and the long-run growth rate. The holistic analysis highlighted that regulatory quality and civil liberties needed to be well ensured to attain economic growth in the long run as they showed a significant positive relationship with the growth of the South Asian region. The short-run analysis of the variables depicted that there is no strong linkage between the growth and instabilities in the political arena, as the majority of the proxies of political instability exhibited an insignificant relationship with economic growth except regulatory quality.

Keywords: Economic growth; PARDL model; Political Instability; South Asia
Knowledge of viral load, PrEP, and HIV-related sexual risk among men who have sex with men in the Waterloo region
Authors: Tassiopoulos Karina , Travers Robb , Cameron Ruth , Coulombe Simon , Davis Charlie E. , Wilson Ciann L. , Woodford Michael R. , Coleman Todd
Published: December 2022

Gay, bisexual, and other men who have sex with men (GBMSM) remain most disproportionately affected by HIV in Canada. HIV-related sexual risk behaviours have been linked to high HIV risk among GBMSM, but prior research has not focused on knowledge of viral load, and the risk it presents for HIV acquisition. The purpose of this study was to explore the relationship between HIV-related sexual risk behaviour and knowledge of viral load among GBMSM. A cross-sectional survey was conducted using a convenience sample of individuals age 16 and older who self-identified as LGBTQ and lived, worked, or resided in the Waterloo region, an urban-rural area in southwestern Ontario ( N = 526). Responses were analyzed from those identifying as GBMSM ( N = 269). Logistic regression models were created to explore sociodemographic, outness, social support, and HIV-related sexual risk variables associated with knowledge of viral load. Multivariable regression models were built to explore the same associations while controlling for confounders. HIV risk was not associated with knowledge of viral load in bivariate or multivariable analyses. Point estimates for low/negligible (odds ratio [OR] 1.10; 95% CI 0.46–2.51) and high risk (OR 1.88; 95% CI 0.68–5.20) suggest trends of higher knowledge with increased HIV risk. Men who engage in sexual risk behaviour may have increased sexual health literacy and awareness of biomedical interventions (e.g., pre-exposure prophylaxis, or PrEP) that reduce HIV risk. Policies are needed that promote acceptance of sexual orientation, improve awareness and access to PrEP, and ensure optimal delivery of HIV education to at-risk groups prior to engagement in higher risk activities.
СВІТОЗАР ДРАГОМАНОВ ТА ЙОГО РОДИННЕ ОТОЧЕННЯ В КИЄВІ (1917-1921 РОКИ)
Authors: ДВІРНА Катерина
Published: December 2022

Метою статті є комплексне вивчення життя та діяльності Світозара Драгоманова та його родинного оточення в Києві в період Української національної революції 1917-1921 рр., аналіз чинників становлення С. Драгоманова як професіонала та політика. На основі вивчення документальних і наративних джерел зроблено спробу реконструкції соціального портрету С. Драгоманова як одного з представників української інтелігенції тієї доби, активного пропагандиста соціал-демократичних ідей та федералізму, а також прихильника європейських цінностей демократії, громадянської рівності й верховенства права. Методологія дослідження окреслена принципами історизму, системного аналізу, об’єктивності та комплексності. Методи історичної біографістики та просопографії дали змогу схарактеризувати становлення особистості С. Драгоманова в конкретних історичних умовах. Проблемно-хронологічний метод забезпечив дослідження в хронологічній послідовності та динаміці професійної та політичної діяльності С. Драгоманова, зробив можливим аналіз еволюції його поглядів на суспільно-політичні та економічні процеси в Україні в роки Національної революції. Наукова новизна. Постать Світозара Драгоманова, його життя та діяльність у період Національної революції 1917-1921 рр в Україні донині залишається поза увагою дослідників. В українській історіографії відсутні праці на цю тему, а сучасні напрацювання науковців лише фрагментарно вписують окремі сюжети життєпису сина М. П. Драгоманова в історичний контекст окресленого періоду. Авторкою вперше введено до наукового обігу та проаналізовано виявлені в Центральному державному архіві вищих органів влади та управління України документи, а саме: нотатник С. Драгоманова за 1916-1921 рр. та його автобіографію періоду окупації (1943 р). На основі цих та інших джерел авторка статті розкриває основні етапи формування С. Драгоманова як особистості, вплив на нього тітки Олени Пчілки (матері Лесі Українки), «українського оточення» їхньої родини, а в студентські роки та роки революції – вплив його вчителів М. Довнар-Запольського, Л. Яснопольського, С. Остапенка, О. Русова.
СПІЛКА БЕЗВІРНИКІВ УКРАЇНИ (ДРУГА ПОЛОВИНА 1920-Х РОКІВ): СТАНОВЛЕННЯ ТА СТРУКТУРА
Authors: ЖУРБА Михайло , ПОТИЛЬЧАК Олександр , ЖОЛОБ Михайло
Published: December 2022

Мета статті. У контексті антирелігійної політики більшовиків другої половини 1920-х рр. розкрито передумови створення, організація та структура Спілки безвірників України. Методологія дослідження – принципи науковості, об’єктивності, історизму; методи аналізу, класифікації, синтезу, історико-генетичний та історико-типологічний. Наукова новизна. Важливим завданням компартійного режиму в Україні було забезпечення виховання людини нового типу, погляди якої мали б цілком узгоджуватися з марксистсько-більшовицькою ідеологією. Зважаючи на цей історичний контекст, схарактеризовано передумови створення Спілки безвірників України, зокрема встановлено зв’язок між виникненням організованого антирелігійного руху в Україні і поширенням атеїстичної пропаганди через «спеціалізовані» громадські об’єднання в радянській Росії. Визначено проблеми, що спіткали активістів антирелігійної пропаганди на початковому етапі їхньої організаторської діяльності. Спостережено зростання мережі осередків Союзу безбожників в Україні та проаналізовано організаційне оформлення його української філії – Спілки безвірників. Окреслено процедуру створення первинних безвірницьких осередків. Схарактеризовано районні, окружні та центральну ланки управління громадською організацією. Простежено роботу Всеукраїнського з’їзду безвірників, що відбувся навесні 1928 р. і став етапною подією в розвитку антирелігійного руху в Україні, засвідчивши його остаточне організаційне оформлення. У структурі Спілки безвірників визначено місце національних секцій, покликаних розгортати атеїстичну роботу серед етноспільнот України.
Microbial Degradation of Plastics
Authors: Zhang Hongli , Dierkes Robert , Streit Wolfgang R.
Published: December 2022

Microbial degradation in the environment is initiated by abiotic (nonliving physical or chemical) processes. Mechanical weathering and other mechanical processes are the main drivers of the initial degradation. This article presents an overview of weathering and biodegradation. It summarizes the main synthetic polymers that are released and available for bacterial and fungal decomposition. The article also presents a detailed discussion on the enzymes that are involved in plastic degradation, and the measurement of polymer degradation.
Plastic Design Methods
Authors: MacLean-Blevins Mark T.
Published: December 2022

This article presents the benefits of selecting plastics for products to be manufactured. It discusses the four key considerations for plastic part design: material, process, tooling, and design. The article provides a detailed discussion of the development sequence for plastic parts. The basis for the development sequence is twofold: first, to create the best solution for the application, and second, to minimize potential project risks through careful and thoughtful work habits.
Environmental Stress Cracking
Authors: Cruz Javier C. , Jansen Jeffrey A.
Published: December 2022

While there are many fracture mechanisms that can lead to the failure of a plastic component, environmental stress cracking (ESC) is recognized as one of the leading causes of plastic failure. This article focuses on unpacking the basic concepts of ESC to provide the engineer with a better understanding of how to evaluate and prevent it. It then presents factors that affect and contribute to the susceptibility of plastic to ESC: material factors, chemical factors, stress, and environmental factors. The article includes the collection of background information to understand the circumstances surrounding the failure, a fractographic evaluation to assess the cracking, and analytical testing to evaluate the material, design, manufacturing, and environmental factors.
FINANCIAL RESOURCES AS A STRATEGIC DRIVER ON PERFORMANCE OF AGENCY BANKING IN COMMERCIAL BANKS IN KENYA
Authors: Martin N. Mbugua  , Margaret Oloko  , Jared Deya
Published: December 2022

The study sought to establish the influence of financial resources on the performance of agency banking in commercial banks in Kenya. The study reviewed previous studies done to support the research objectives from which the research gaps were extracted. The study used descriptive survey research design. The target population for this study was the 18 commercial banks in Kenya licensed by Central Bank of Kenya to operate agency banking. The branch managers, ICT managers, operations managers, human resource managers and customer relations managers were the key targets respondents in the study. Primary and secondary data was collected using questionnaires and checklist guide respectively. Inferential analysis was carried out to establish the relationship between the independent variables and the dependent variable. The study established that Financial Resources had a positive significant influence on the performance of agency banking among the commercial banks in Kenya. The financial resources availed to agency banking through shareholders’ fund, liquidity ratio and value of assets also positively influenced the performance of agency banking. The study concluded that financial resources were essential in steering the performance of agency banking thus recommending that the commercial banks through the management ought to uphold these strategic drivers in order to enhance the performance of agency banking.
SPOR LİSELERİ ÖĞRENCİLERİNİN SPORTMENLİK ALGISININ İNCELENMESİ
Authors: GÜL Coşkun , BİNGÖL Şükrü
Published: December 2022

Bu araştırmada spor liseleri öğrencilerinin sportmenlik algısının incelenmesi amaçlanmıştır. Spor ve sportmenlik kavramı birlikte ifade edildiğinde sporun ve sportmenliğin uyum içinde olması gereken kavramlar olduğu görülmektedir. Spor ve sportmenlik birbirini tamamlamak zorunda olan kavramlardır. Spor, sportmenlik sayesinde belli bir ahenge kavuşur ve sportmenlikte spor ile birlikte bir anlam kazanır. Bu bağlamda çocuk ve genç yaştaki insanların, spor ve onun içeriğinde barınan bazı kavramları anlamlandırmaları ve o bilinçle hareket etmeleri sportif hedeflere varma noktasında isabetli bir yöntem olacaktır. Bu araştırmada, veriler SPSS 24.0 programı kullanılarak değerlendirmeye alınmıştır. Araştırma ile ilgili veriler aritmetik ortalama ve standart sapma değerleri üzerinden yorumlamaya tabi tutulmuştur. Ayrıca bu araştırmada formal eğitim kapsamında spora yönelik bir eğitim veren spor liselerinin yetiştirmiş olduğu öğrencilerin sportmenlik kavramına yönelik neyi algıladıklarının tespit edilmesi araştırma konusu olarak belirlenmiştir. Çünkü temel spor eğitiminin verildiği bu okullardan mezun olan öğrencilerin sporun bu alanında hem teorik anlamda hem de uygulama anlamında hangi düzeyde olduklarının bilinmesi yapılacak bir takım proje ve benzeri çalışmalara öncülük etmiş olacaktır. Araştırma sonuçları incelendiğinde öğrencilerin sportmenlik kavramını algı düzeyinin yüksek oranda olduğu söylenebilir.
How to recognize violence and prevent it
Authors: Bondarenko N.
Published: December 2022

The article highlights the problem of violence and its consequences for the psychological development of the individual, analyzes the principles of working with victims of domestic violence. Violence has probably always been a part of human existence. Its various manifestations can be seen in all corners of the world. Only recently has special attention been paid to this issue. The topic of violence and aggression has become one of the most relevant since the end of the 20th century. The topic of domestic violence is gradually beginning to be discussed, mainly thanks to the efforts of women's public organizations, specialists in the field of gender and social studies. Under public pressure, active state aid to crisis centers and shelters for women who have survived violence began. In our country, the problem of domestic violence began to be paid attention to quite recently. The number of scientific studies examining marriage in relation to violence and child abuse is limited. International attention to the problem of domestic violence is highlighted by numerous discussions at UN congresses on women's issues.
Professional stress of beginning psychologists
Authors: Kurinna І.
Published: December 2022

In this article discusses the importance of studying stress and its concept. The stages and their consequences of stress are reflected according to H. Selye. The definition of occupational stress. The main factors and components of occupational stress of novice psychologists are analysed. The definition of occupational stress and syndrome of stress is given. The opinion of scientists is reflected on nature and factors due to which it arises. Stress and its manifestations. In detail stress is considered it is informative, communicative and emotional, according to scientists of their forming, manifestations and consequences. The main features of competence and professionalism of psychologists are analysed. The features of informative, of communication and informative stress are described in professional activity of psychologist. Describes the factors that cause the transformation of chronic stress into burnout that is considered in the works of scientists. The problem of finding out the factors of stress development and regulating its level is considered. Professional stressors and their factors are described in detailed. Focused attention on that occupational stress in psychologists can become a serious threat for successful development of professional activity, and sometimes to the health too. Conclusions are made about occupational stress and influence on work of psychologist.
World paradigm break-2022: lessons, implications and prospects
Authors: Kultenko V.
Published: December 2022

In the modern world paradigmatic changes are taking place. They are caused by the full-scale invasion and military actions of the Russian Federation against Ukraine. The long and bloody war became unexpected for the world in terms of its character, content and possible consequences. The heroic resistance of the Ukrainian people, indomitable defense of their own freedom and right to self-determination forced the world to reconsider its attitude towards Ukraine. After all, during this war, in front of the eyes of the world, the formation of a renewed political subject of the Ukrainian nation is taking place, which is fighting for its right to exist with weapons. The resilience of Ukrainians requires an appropriate response from the world, because after February 24, the world has changed and is being tested for strength: from the threat of nuclear war to global food or migration crises. An additional test for the world was a crisis of an existential and moral character, associated with an ethical choice between justice and goodness on the one hand and profit and moderate comfort on the other. Concepts of good and evil in conditions of brutal bloodshed are forced to adjust. After all, the issue of the need for supplies of lethal weapons for the needs of the Armed Forces is extremely acute. It poses a threat to combatants and civilians in the war zone. So, how to qualify the supply of lethal weapons to a country that has become a victim of barbaric military aggression - is it good or bad? And how long can such military aid last? The war continues in the center of civilized Europe in the 21st century. The world has already experienced two world wars. However, this experience did not help prevent further bloodshed and mass atrocities by the occupiers. With new strength in the conditions of the collision of the postmodern reality of today with the militant archaism of the past, the refrain sounds: "Never again!" The purpose of the work is to study the complex socio-historical circumstances in which the formation of Ukrainian political identity takes place on a new worldview platform, when the rational order of things is maximally supplanted and replaced by irrational-willed factors of life organization.
Informational Support of Journalist’s Environmental Education in the Context of Sustainable Development
Authors: Kharchenko S. , Shynkaruk V.
Published: December 2022

Introduction. The article is devoted to informational support for environmental education of journalists through electronic educational resources. Any product, in particular, educational, needs informational support. Promotion of an educational product is no less important than its creation.Methods. A number of general scientific and linguistic methods were used in the research. In particular, the methods of analysis, synthesis, deduction and induction, the descriptive method are used to justify the theoretical base of the research and generalize our own observations. The terminological analysis is applied to the definitions of the "ecological education" concept that functions in the scientific discourse and media space. The statistical method was used to determine the level of awareness of students about the available educational resources in the Internet space.Results and discussion. The concept of "ecological education" was studied, and its refined definition was proposed. Attention was drawn to the fact that effective environmental education is not the transmission and assimilation of information, it is the formation of a system of knowledge and values of nature conservation, as well as the skills of joint implementation of effective environmental actions. It is noted that formal, non-formal and informal environmental education will increase the level of functional literacy of journalists, reduce the inflation of environmental knowledge, which will allow journalists to correctly understand environmental problems, interpret and apply appropriate approaches and methods to solving environmental issues arising in local, regional, national and global contexts, as well as apply their creative and aesthetic skills within the space of environmental journalism.It has been established that information support expands access to education for anyone and removes geographical, spatial and time frames for learning, saves time and money, helps to navigate formal education offers, choose programs and/or platforms for non-formal and informal education. Educational and scientific sites for the exchange of environmentally oriented information were considered. It was emphasized that lifelong learning of a journalist is important for his long-term success in the career and is a mandatory condition for the successful implementation of the fourth goal of sustainable development of Ukraine. The components of the informational support of the journalists’ eco-education were distinguished and the level of awareness of students about the available educational resources in the Internet space was determined. We see the prospects for further research in the following: to develop the concept of a platform where information about formal, non-formal and informal environmental education, etc., would be accumulated.
A Crytical Discourse Analysis of the Ukrainian War Refugees’ Image in British Press
Authors: Pavlichenko L. , Popivniak O.
Published: December 2022

Introduction. The article examines the peculiarities of the image construction of the Ukrainian war refugees as the consequence of political changes that swept the world in the war in Ukraine unleashed by Russia on February, 24, 2022. The relevance of the study is due to the growing scientific interest in the phenomenology of the discourse of migrants and refugees and its aspects.Methods. The research of mass media discourse was conducted in the context of critical discourse analysis (CDA).Results. The study based on the material of the British press analyses the mechanisms of the refugees’ image formation. As an instrument of the impact on the society, mass media discourse is structured and meets certain requirements. We identify the discourse topics where the Ukrainian refugees are presented as the threat to European security, as the most socially vulnerable individuals suffering the consequences of the war in their home country or as heroes forced to risk their lives. As social actors, Ukrainian refugees are represented either as a collective identity, or as individuals. The study concludes about the strategies that form the image of refugees (impersonification, victimization, referential, in-group and out-group framing), about the linguistic means verbalizing the strategies (generalised nouns, numerals, adjectives, idioms and collocations), and the stylistic figures (metaphors, allusions, oxymoron, hyperbolas, personification).

Discussion. The prospects for further exploration we see in the study of the image of the Ukrainian refugees in the social media discourse.
Treatment of Patients after Pulmonary Vein Isolation in Persistent Atrial Fibrillation - Combined Use of a High-Density Map and Robotic Navigation
Authors: Bychkov Yuriy , Doneva Zdravena , Buchter Björn , Kreuzer Margarita , Schulze P. Christian , Hügl Burkhard
Published: December 2022

Objectives and Background: Atrial fibrillation (AF) is still associated with higher recurrence rate. This is prospective study of Redo pulmonary vein isolation (PVI) combined with remote magnet navigation. We have done high density mapping and in retrospective Analysis we tried to find criteria for better Ablation success. Materials and Methods: 50 patients (male 36, female 14) with indication for Redo-PVI ware included. A 20 polig multielectrode catheter was used for mapping. Mapping data were collected bevor and after ablation and processed in terms of low-voltage areas bipolar (3 groups: 0.05-0.15 mV, 0.15-0.25 mV, 0.25-0.5 mV) and change in unipolar amplitude at the ablation lesions. The primary endpoint (symptom freedom at 12 months) was evidenced by follow-up examinations at 3, 6,9,12 months. Non-parametric statistical methods were used for variables with non-normal distributions. Trends in success rates were evaluated using the Kaplan-Meier methodology and compared using a log-ranking test. Results: In all analysed low-voltage bipolar groups occurs a change in the distribution after ablation in patients with AF. There are 3 parameters which related with endpoint: area of bipolar signals 0.05-0.15 mV (Me +32%, [95% CI: -10% to +167%], p<0.001), the unipolar amplitude at the applied ablation lesions (Me -0.45mV [95% CI: -0.15 to -1], p<0,001) and unipolar amplitude at the attached ablation lesions (lower amplitude was with recurrence associated, p=0.004). According to ROC analysis and logistic regression: failure to meet all 3 criteria accompanied with a 67% probability of symptomatic recurrence, if all 3 criteria are met, it is expected to have an approximately 81% success rate within the 12 months. Conclusion: Analysis of a high-density map including 3 criteria, help us to improve ablation success.
A New Approach for Dye Removal with a Polymer: Removal of Acid Orange 12 from Aqueous Solution with Shrimp Chitin
Authors: ARACAGÖK Yusuf Doruk , KOŞARSOY AĞÇELİ Gözde , KABALAK Mahmut
Published: December 2022

Chitin, a naturally abundant mucopolysaccharide, is the supporting material of crustaceans, insects, and etc. Chitin and its main derivative chitosan have various applications in medicine, pharmacy, biotechnology, environment, and food engineering because of their nontoxicity, biodegradability, biocompatibility, antimicrobial, and antioxidant properties. Here, research was conducted on the removal of Acid Orange 12, which is among the most used azo dyes in textiles, from aqueous solutions using shrimp chitin, a polymer. To determine the most suitable conditions, different parameters (pH degrees, amount of chitin, amount of dye, contact time) were studied. Chitin was determined to be the most efficient in removing Acid Orange 12 using pH 5 conditions. The adsorption of dye onto chitin followed the Langmuir isotherm and pseudo-second-order kinetic model.
CURRENT ISSUES OF THE ORGANIZATION OF THE CORRESPONDENCE PART OF THE INTERNSHIP PROCESS ON THE CLINICAL BASE OF INTERNSHIP
Authors: Dyachuk D.D. , Zyukov O.L. , Oshivalova O.O. , Biloshitska O.K.
Published: December 2022

Abstract. In the conditions of the rapid development of modern medicine, the search and implementation of new approaches to the study of the diagnostic and treatment process of diseases with the mastery of manual methods are of great importance. The inability to apply acquired knowledge in practice is often the basis of medical errors and ineffective medical measures. There are new requirements for the training program for medical interns using modern medical technologies. Therefore, ensuring the availability of high-quality training for interns on a clinical internship basis should be considered a mandatory component of maintaining the high-quality level of training of medical interns at the current stage of medical reform in Ukraine. This is evidenced by our survey of intern doctors, who emphasized the importance of the availability and staffing of workplaces with awareness of safety techniques, the availability of sufficient volumes of medical care and the availability of standards of medical care based on internships, training with a sufficient level of comfort and a level of timely awareness.
MEDICAL AND SOCIAL SUPPORT OF DENTAL CARE IN THE CONTEXT OF TODAY'S CHALLENGES
Authors: Yelenskyi V. Y.
Published: December 2022

Resume. The article deals with current issues in the organization of providing dental care to the population in today's conditions. Regulatory documents were studied and modern and global approaches to the prevention of common dental diseases in the population were analyzed. The influence of the organization of preventive work in the dental industry on the prevention of common dental diseases in the population has been clarified.

Introduction. Dental health is an integral part of the overall health of each individual and society in general. The medical and social significance of the problem of oral cavity diseases is determined not only by its significant spread but also by the high rate of complications [5, 8].

The process of treatment of patients with diseases of the oral cavity should be complex and should be part of a multidisciplinary approach and should be carried out with the aim of prevention, complications, or weakening of the functional overload of the periodontium and the tooth as a whole. According to scientists in Ukraine, the rate of dental morbidity among adults and children reaches 93%, which means that this is the proportion of the country's population that needs dental care.

It is worth noting that the priority in the activities of executive authorities at all levels is the provision of high-quality and affordable medical care with the orientation of the health care system on the prevention of diseases, a safe and health-friendly environment for human life (working, living, training, relaxing, nutrition), healthy lifestyle of the population and improvement of the demographic situation. The legal regulation of the mentioned activity is ensured by the Law of Ukraine "Basics of the Legislation of Ukraine on Health Protection" dated November 19, 1992 No. 2802-ХІІ (as amended from November 6, 2017), where several articles indicate measures for the prevention of diseases. In the aforementioned Law of Ukraine, the organizational aspects of prevention of all classes of diseases are singled out, in particular, Article 4 "Basic principles of health care" emphasizes one of the principles of the approach to health care, which is preventive [14].

The purpose of the article. To analyze domestic and global approaches to the prevention of common dental diseases of the population. To conduct an analysis of modern trends in medical care and medical and social support of dental care to the population in the context of modern challenges.

Research materials and methods. Analysis and generalization of data based on domestic and foreign sources. Used methods of systemic and structural-logical analyses. The materials were documents and information sources, normative legal acts of Ukraine regarding medical and dental care for the population.
Features of the bioelectrical activity of the brain and cerebral hemodynamics in patients with hypertensive dyscirculatory encephalopathy and hypothyroidism
Authors: Kovalenko Olga Ye. , Litvin Olena V.
Published: December 2022

Encephalopathy is common in people of working age. In the last decade there was an important question the relationship of thyroid and cerebrovascular disease. The aim of the study was to investigate the characteristics of the brain’s elektorogenezis and cerebral hemodynamics in patients with hypertensive encephalopathy and related dyscirculatory hypothyroidism.

We examined 97 patients, including 60 people with the HDE and the associated hypothyroidism and 37 - with the HDE without hypothyroidism.

The fact, that bioelectrical activity of the brain in patients with hypothyroidism and related HDE was mostly characterized by desynchronization and disorganization of the cortical rhythm, was revealed during the study. Changes revealed by the EEG reflected the presence of metabolic and hemodynamic disturbances of the brain. Also, in patients with GDE and accompanying hypothyroidism, according to the duplex scanning of cerebral vessels, there is a significant decrease in cerebral blood supply and structural changes in vessels with a decrease in the elasticity of the common carotid artery and vertebral arteries and a decrease in cerebral reactivity accordingly. Thus, the comorbidity of HDE and hypothyroidism appears credible changes in the functional activity of the brain and decrease in cerebral reactivity.
THE ROLE OF SKIN CARE PRODUCTS AND EARLY FOOD FOR THE PREVENTION OF ATOPIC DERMATITIS IN INFANTS
Authors: Mozyrska O.V. , Slyusar N.A.
Published: December 2022

The aim of the study

The aim of this study was to assess the value of interventions aimed at improving the skin barrier and skin care products, as well as breastfeeding and early introduction of complementary foods, for the primary prevention of atopic dermatitis (AD) and food allergy in infants.

Materials and methods

We started a survey in the period from May 2022, which continues to this day. The survey was conducted with the help of Google forms and distributed on the Internet, as well as parents of children who applied for help at Kyiv children’s clinical hospital No. 2 and MC "Allergolog" were interviewed. The relationship between intervention methods and the development of AD and food allergy was determined using the odds ratio (OR) with a 95% confidence interval (CI).

Results

According to the survey data, 42,2% of children received moisturizing cream, parents of 16,5% of children reported using moisturizing oil for bathing the child, 12,4% of parents used less soap and bathed the child less often, 28,9% reported that they did not use none of these methods and means of care.

AD occurred in 23,7% of children interviewed. The odds ratio for the moisturizing cream group was 68,6 (CI 3,9-1201,5), p=0,004, for the groups that used moisturizing oils for bathing – 8,9 (CI 0,4-197,6), p= 0,17, for the group where the intervention was a reduction in bathing and using soap – 7,1 (CI 0,3-186,0), p=0,24.

18,6% of respondents reported a reaction to food that occurred in the child within 2 hours after consumption. We have not found any role of emollients (OR=1,4, CI 0,4-4,9), p=0,56, moisturizing oils for bathing (OR=0,3, CI 0,03-2,6), p=0,27, and reduced use of soap and water (OR=1,4 (CI 0,3-7,2), p=0,66 for the development of food allergy.

The duration of breastfeeding (more than 3 months) did not affect the risk of developing AD (OR = 0,1, CI 0,01-2,6), p = 0,19, or food allergy (OR = 1,3, CI 0,3-6,9), p=0,74. Also, the role of earlier introduction of supplementary food on the development of AD and food allergy was not shown: the OR for AD was 0,9 (CI 0,3-2,7), p=0,8, the OR for food allergy was 0,8 (CI 0,2- 2,9), p=0,76.

Conclusions

This study did not reveal the protective role of skin care products, breastfeeding, and early introduction of complementary foods for the development of AD and food allergies in children. A larger survey will allow us to study the effect of emollients and other preventive measures on the development of food allergies in a group of children with AD.
Current Revision of GINA (Main Provisions) for Adults and Features of Management of Patients with Bronchial Asthma in Conditions of Social Disasters
Authors:   SO “National institute of phthisiology and pulmonology named after F. G. Yanovsky NAMS of Ukraine”, Feshchenko Yu. I. , Polianska M. O.
Published: December 2022

Abstract. The main document that forms the basis of international and national guidelines for the management of patients with bronchial asthma (BA) — the Global Initiative for the Management of Patients with Bronchial Asthma (GINA) — is revised every year. The clarifications of the current year concern both the diagnosis of primary asthma and the confirmation of this diagnosis in patients, who already receive controller therapy. The diagnostic algorithm for patients already receiving control therapy is presented (approaches for initial diagnosis and for diagnosis verification in patients on basic control therapy are different). Emphasis is placed on the need to carry out functional pulmonary tests in the diagnosis and monitoring of asthma patients, their high informativeness. There is an ongoing debate and calls for its continuation regarding the definition of severity of asthma, especially mild. Asthma treatment pathways (Tracks) are clearly defined, they are distinguished by drugs that are used to relieve symptoms (if necessary): fixed combinations of low-dose inhaled corticosteroids with formoterol — Track 1, or short-acting beta2 -agonists — Track 2. Emphasis is placed on the role of education and self management of patients with BA in conditions of limited access to medical care. Providing an agreed, written, personalized action plan that advises on the use of basic therapy, recognition of signs of worsening, and what appropriate interventions the patient can take on their own is a critical component of effective asthma self-management. Effective implementation requires a whole system approach that combines the active involvement of patients in training with the motivation of professionals who have to conduct this training and monitor its process. Our task is to bring this information to the widest circles of doctors and asthma patients, to widely implement patient education and self-management skills. Key words: bronchial asthma, medical care, treatment, difficult life situations, emergency, crisis
ONE-POT MCR REACTION VIA DIFFERENT BASE USED AS CATALYST ANDPEG-400 AS A SOLVENT
Authors: Nitone Umesh , Mahida Jayaveersinh , Agrawal Seema
Published: December 2022

Our motto for this work is green and natural resources use for the development of multicomponent reaction (MCRs) significant approach for the fabrication of polyfunctional molecules in an operatively easy and atom-economic manner, and the finding of novel MCRs appeal to various building blocks. Herein, the latest pyran-based phthalazinone pyrazole hybrids were synthesized by a facile one-pot MCR done by triethylamine, di-isopropyl ethyl amine (DIPEA), tripropylamine (TPA) as a catalyst. Check study led to the recognition of tripropylamine (TPA) with PEG-400 as the potential catalyst and green solvent, respectively, and the reusability of PEG-400 up to 5 cycles. This protocol opens a new perception for the introduction of rational design and the building blocks of MCRs.
MOLECULAR MODELLING STUDIES AND LARVICIDAL POTENTIAL OF PHE (POLYHERBAL EXTRACT) OF SELECTED INDIAN MEDICINAL HERBS
Authors: P. Manorama  , Aruna Valmiki , Angajala Gangadhara
Published: December 2022

The present study attempts to investigate the larvicidal activity of methanolic extract of PHP (Poly Herbal Powder) of selected Indian Medicinal herbs against blood-feeding mosquito larvae namely Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus. The major compounds from the methanolic extract of PHP were identified through GCMC analysis. Molecular modeling studies were examined to predict the binding interactions of major compounds with a sterol carrier protein (SCP-2). The results obtained from larvicidal activity demonstrated that the methanolic extract of PHP exhibits appreciable LC50 against A.stephensi and C.quinquefasciatus (LC50: 453.30 & 462.17 ppm). Furthermore, molecular docking studies revealed two bioactive compounds namely Geranyl isovalerate (-8.0 K.cal/mol) and Marmelosin (-7.6 K.cal/mol) with greater binding affinity with SCP-2 receptor as compared to positive control Temephos (-6.8 K.cal/mol).
RELEASE KINETIC POLYPHENOL OF ACTIVE EDIBLE SAGO STARCH-CHITOSAN FILM CARRYING EXTRA VIRGIN OLIVE OIL
Authors: M.Hasan  , Rahmayani R.F.I. , Hazi W.R. , Rusman
Published: December 2022

The kinetics of polyphenol release from active films made from sago starch and chitosan with the addition of EVOO have been studied. The purpose of this study is to determine the release kinetics of polyphenols from EVOO added to the active film. Total phenol content of 1%, 2%, and 5% EVOO added to the film was determined by the FolinCiocalteu method of 0.1757, 0.1868, and 0.11 mgGAE/g. The kinetic release of polyphenols was tested using three kinetic models, such as zero order, first order, and Higuchi, by comparing the active films in two solvents, namely water and 10% (v/v) aqueous ethanol solution. The highest release occurred in the active film with 2% EVOO (CHSS2) in the two solvents. The release of Polyphenol active film in 10% ethanol followed the release of Higuchi, while CHSS1 and CHSS5 in H2O solvent followed the first-order release.
SYNTHESIS AND ANTI-INFLAMMATORY, ANTIOXIDANT STUDIES OF NOVEL CHALCONES-BASED ISOXAZOLE DERIVATIVES
Authors: S. Abibindhu  , Nair Smitha , C. Kannan
Published: December 2022

Our previous work identified various novel Chalcones (I-III) produced by mixing the equimolar amount of Ferrocene aldehyde and different substituted acetophenones which has a strong base. Hence, in the present study, novel various Chalcones (I-III) were treated with hydroxylamine hydrochloride to form various Isoxazoles (Ic-IIIc). The synthesized novel chalcone-based Isoxazole derivatives were determined by spectroscopic techniques such as1H,13C-NMR, FT-IR,and UV. Further, these products were evaluated for antimicrobial studies and antioxidant susceptibilities through DPPH radical scavenging method. The synthesized isoxazole (Ic) was subjected to a study of their anti-inflammatory activity(COX and LOX) assay.