bluuebunny/crossref_metadata_2025 huggingface dataset:
Improvement of Pichia kudriavzevii Egyptian isolate for keratinase production
Authors: Khalil Bigad E. , Ibrahim Hayam F. , Abd El-Aziz Nagwa M.
Published: June 2022

Background and objective

Keratinases are gaining considerable momentum in green technology because of their endowed robustness and multifaceted application potentials, such as valorization of keratinous agro-waste. Therefore, the production of novel keratinases from relative yeasts grown in agro-waste formulated medium is cost-effective and imperative for the sustainability of thriving bioeconomy.

Materials and methods

A total of 51 yeast isolates were isolated from 10 different poultry farms and assayed for keratinase-specific activity. Molecular identification of the high-efficiency keratinase-producing yeast isolate was done by PCR amplification, employing sequencing of internal transcribed spacer regions of yeast. Mutagenesis induction with ethidium bromide, ultraviolet, and ethyl methane sulfonate (EMS) was done in a multistep mutation-induction process for creating super keratinase-productive mutants. Response surface methodology optimization of culture conditions for high-productive mutant was carried out using different parameters such as incubation time, pH, carbon sources, and nitrogen sources to test keratinase activity. Inter-simple sequence repeat (ISSR-PCR) was applied to study the genetic diversity of isolated Pichia kudriavzevii YK46 compared with their five mutants.

Results and conclusion

The results indicated that the isolate with the highest keratinase activity was isolate no. 46, which recorded 164.04 U/ml. It was identified as P. kudriavzevii and was submitted to NCBI under accession number ‘OK092586’. It was named as P. kudriavzevii YK46. Results of mutagenesis showed that the best keratinolytic efficiency mutant was designated as EMS-37, which showed an activity of 211.90 U/ml. After response surface methodology optimization of culture conditions for mutant EMS-37, the maximum keratinase activity was noted after an optimized condition at pH 5, 72 h of incubation time, 2.5% glucose, and 2.5% beef extract (as carbon and nitrogen sources), with an activity of 240.172 U/ml (Run3). Inter-simple sequence repeat showed that the highest total and polymorphic with unique bands were revealed in the mutant EMS-37, with 82 and 54 bands, respectively, whereas the mutant EMS-56 showed 72 and 44 bands, respectively, compared with the wild-type strain P. kudriavzevii YK46, with 86 and 58 bands, respectively. The data obtained showed that mutant EMS-37 was the highest producer of keratinase enzyme. It had seven unique bands. These bands might be related to the increase in the productivity of keratinase enzyme.
The therapeutic effect of balloon dilatation with different duration for biliary duct calculi
Authors: Yu Zhi Yuan , Liang Chen , Yang Shi Yu , Zhang Xu , Sun Yan
Published: June 2022

Objective:

To systematically evaluate the application effect of endoscopic papillary balloon dilatation (EPBD) with different balloon dilatation duration for biliary duct calculi, and find the most appropriate dilatation duration for EPBD using a network meta-analysis.

Materials and Methods:

PubMed, Embase and Cochrane Library databases were searched for relevant randomised controlled trials (RCTs) published up to August 2020. Node split, consistency and inconsistency models analysis were all conducted in network meta-analysis.

Results:

Eighteen RCTs with 2256 participants were finally analysed. EPBD was divided into four categories based on balloon dilatation duration, including EPBD (P0.5), EPBD (>0.5, ≤1), EPBD (1, ≤2) and EPBD (>2, ≤5). Compared with EPBD (>0.5, ≤1), EPBD (>2, ≤5) had a lower risk of early complications (odds ratio [OR] = 0.23, 95% credible interval [CI] = 0.05–0.96) and post-endoscopic procedure pancreatitis (PEP) (OR = 0.17, 95% CI = 0.03–0.72). Endoscopic sphincterotomy (EST) tended to have less need for mechanical lithotripsy (OR = 0.37, 95% CI = 0.16–0.88) and PEP (OR = 0.26, 95% CI = 0.08–0.71) than EPBD (>0.5, ≤1). EPBD (>2, ≤5) was the safest endoscopic procedure with respect to early complications (surface area under cumulative ranking curves [SUCRA] = 79.0) and PEP (SUCRA = 85.3). In addition, EPBD (>2, ≤5) and EST had the highest probability of being the best (SUCRA = 82.6) and the worst (SUCRA = 10.8), respectively, regarding late complications.

Conclusion:

EPBD and EST are two methods used to treat uncomplicated choledocholithiasis (stone diameter <10 mm and stone number <3). The extension of balloon dilatation duration has no significant influence on successful stone removal in the first endoscopic session or preventing the need for mechanical lithotripsy. However, it can reduce the risk of early complications, especially PEP. What's more, EPBD seems to have less late complications compared with EST, and the effect of prolonged balloon dilatation duration on late complications still needs to be further explored. Therefore, 2–5 min is the recommended dilatation duration range for EPBD using balloon with ≤10 mm diameter. Further research based on a specific population and with a longer follow-up time are needed.
A case of aseptic bilateral cavernous sinus thrombosis following a recent inactivated SARS-CoV-2 vaccination
Authors: Nusanti Syntia , Putera Ikhwanuliman , Sidik M. , Edwar Lukman , Koesnoe Sukamto , Rachman Andhika , Kurniawan Mohammad , Edi Tarigan Tri Juli , Yunus Reyhan Eddy , Saraswati Indah , Zoraida Soraya Siti Halida , Pratomo Tiara Grevillea , Nora Rina La Distia
Published: June 2022

This case report aims to describe the first report of bilateral aseptic cavernous sinus thrombosis (CST) with a recent history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. A 50-year-old woman presented with bilateral proptosis, decreased vision, and ophthalmoplegia 16 days following CoronaVac® vaccine. The visual acuity of the left eye was 20/150, while the right eye was no light perception with a hyperemic optic nerve head. She had a history of hyperthyroidism and currently on warfarin consumption. Laboratory results depicted elevated free T4, free T3, international normalized ratio, and low protein S and C. Magnetic resonance imaging showed bilateral CST, and high-dose methylprednisolone along with fondaparinux was given. The symptoms were significantly resolved, with the visual acuity of the left eye being improved to 20/20 but not the right eye. Bilateral CST has not been previously reported following inactivated SARS-CoV-2 vaccination. The underlying systemic conditions should be taken into consideration for the possibility of the inactivated SARS-CoV-2 vaccine-related event.
Effects of Boundary Layer and Local Volumetric Cells Refinements on Compressor Direct Noise Computation
Authors: Pietroniro Asuka Gabriele , Trigell Emelie , Jacob Stefan , Mihaescu Mihai , Abom Mats , Knutsson Magnus
Published: June 2022

The use of turbochargers with downsized internal combustion engines improves road vehicles’ energy efficiency but introduces additional sound sources of strong acoustic annoyance on the turbocharger’s compressor side. In the present study, direct noise computations (DNC) are carried out on a passenger vehicle turbocharger compressor. The work focuses on assessing the influence of grid parameters on the acoustic predictions, to further advance the maturity of the acoustic modelling of such machines with complex three-dimensional features. The effect of the boundary layer mesh structure, and of the spatial resolution of the mesh, on the simulated acoustic signatures is investigated on detached eddy simulations (DES). Refinements in the core mesh are applied in areas of major acoustic production, to generate cells with sizes proportional to the local Taylor microscale values. Such an educated guess allows for quality enhancement with a smaller increase in computational costs as compared to more general overall refinements. The reflection-free simulation results are validated against experiments. The experimental data were post-processed with methods from the two-port theory to represent pure acoustic source power density for the acoustic modes, cleaned from test-domain-specific reflections. A detailed comparison between experiments and numerical simulations is carried out. As a result of this study, the most critical parameters for the numerical prediction of turbocharger noise are presented. The results can, furthermore, be used to improve the understanding of grid construction when predicting noise signature for compressor flows.
Calibrating a Real-time Energy Management for a Heavy-Duty Fuel Cell Electrified Truck towards Improved Hydrogen Economy
Authors: Anselma Pier Giuseppe , Spano Matteo , Capello Marco , Misul Daniela , Belingardi Giovanni
Published: June 2022

Fuel cell electrified powertrains are currently a promising technology towards decarbonizing the heavy-duty transportation sector. In this context, extensive research is required to thoroughly assess the hydrogen economy potential of fuel cell heavy-duty electrification. This paper proposes a real-time capable energy management strategy (EMS) that can achieve improved hydrogen economy for a fuel cell electrified heavy-duty truck. The considered heavy-duty truck is modelled first in Simulink® environment. A baseline heuristic map-based controller is then retained that can instantaneously control the electrical power split between fuel cell system and the high-voltage battery pack of the heavy-duty truck. Particle swarm optimization (PSO) is consequently implemented to optimally tune the parameters of the considered EMS. For the aim of this study, the calibration optimization objective involves minimizing the hydrogen consumption estimated by simulating the heavy-duty truck in the Simulink® model. Simulations entail different driving missions, some of which have been generated by using the VECTO software, i.e. the tool used in Europe to certify the CO2 emissions of new heavy-duty vehicles. Furthermore, dynamic programming (DP) is implemented as an off-line reference EMS approach that can identify the global optimal control trajectory over time by knowing the entire driving mission in advance. The real-time EMS calibrated by means of PSO is demonstrated achieving remarkable hydrogen saving potential, which results being only around 5% worse compared with the global optimal benchmark provided by DP.
Effect of training of women beekeepers on production of beehive products in Ogun State, Nigeria
Authors: Ojo I.H. , Yusuf H.A. , Sennuga S.O.
Published: June 2022

The study investigated the effect of training on production of bee-hive products by women beekeepers. The specific objectives were to describe the socioeconomic characteristics of the women beekeepers in the study area, examine beekeepers’ access to training, determine the percentage of the beekeepers producing each of the bee hive products, and determine the influence of training on production of bee-hive products. A total of 107 women beekeepers were randomly selected as respondents for the study. Data were collected with the use of a structured questionnaire and analyzed using descriptive statistical tools and logit regression analysis. Results on socioeconomic characteristics show that the beekeepers were relatively educated. Friends and relatives, respectively were the most reported marketing outlets and source of information used by the beekeepers. The majority of the beekeepers did not belong to beekeeping cooperative group and lacked access to extension services. About 68% of the beekeepers had access to training. Apart from honey and bee-wax only very few beekeepers produced other bee-hive products and secondary products. At P>0.01, training positively affected the production of honey (0.100), bee-wax (0.116), bee venom (0.584) and number of secondary products produced (1.378). It however negatively influenced the production of propolis (-0.423) and pollen (-0.298). On the basis of these findings, it is recommended that intensive training programmes on production of different bee-hive products should be given topmost priority for profit maximization and economic diversification.
The Role of Rural Banks in Poverty Reduction among Women: Evidence from Sonzele Rural Bank, Ghana
Authors: Domanban Paul Bata , Asitik Akanganngang Joseph , Addy-Morton Reginald
Published: June 2022

Two-thirds of the world’s poorest and vulnerable, mostly women, live in rural areas, engaging in subsistence agriculture. Hence, in Ghana, rural banking was introduced to provide microcredit services to the marginalised neglected by commercial banks. One of such banks is the Sonzele Rural Bank in Jirapa was set up to offer credit services to improve the living condition, yet poverty in Jirapa is still high. This study, therefore, sought to investigate the role of rural banks in poverty reduction drawing evidence from the Sonzele Rural Bank inJirapa. Using a cross-sectional design, the study employed structured interviews to collect data. The cluster sampling technique was used to select thirteen women’s groups in Jirapa, and purposive sampling enabled the selection of four project staff. Paired-samples t-test and Kendall’s coefficient of concordance were employed in the analysis. The study revealed that credit with education was given to women in groups which enabled them to set up various enterprises and experienced an increase in income and expenditure on education and health thus, reducing poverty in the area. Beneficiaries noted that the issues of high-interest charges, short repayment schedules and absence of insurance policy need attention to make credit a poverty reduction tool.
Unpaid Care Work and its Effect on Gender Equality in Northern Ghana: Evidence from the Jirapa Municipality
Authors: Nanko George Dery , Teng-Zeng Frank K.
Published: June 2022

Globally, women are said to be disadvantaged in the world of paid and/or unpaid work. The study aims at examining the implications of unpaid care responsibilities on gender inequality in the Jirapa Municipality of the Upper West Region, Ghana. The mixed method approach was used for data collection and analyses. In-depth interviews using a questionnaire and an interview guide were used to collect qualitative and quantitative data. The questionnaires were analyzed descriptively using the Statistical Package for Social Sciences version 22 while the interviews were analyzed using the thematic analysis. Findings from the study revealed that inequality caused by unpaid care work is noticeable in the areas of governance, education and paid employment. For instance, whereas the informal sector employs more women, the formal sector employment is largely dominated by men who tend to have sustained jobs. In all these situations women in rural areas tend to be the most affected by gender inequalities. Interconnected variables of vulnerability and suppression including residential status (rural or urban settings) intersect with gender to make rural women worse off in terms of gender inequality. The study recommends cash remittances to unemployed ‘ housewives’ in rural areas and massive infrastructural development of rural communities to guarantee gender responsive public service to women.
Acute and sub-chronic toxicity study of the mixture of Calotropis procera (Ait). R. Br. (Apocynaceae) and Zanthozylum zanthozyloïdes Lam. (Rutaceae) roots bark powder
Authors: Somda Gaétan Donzèo , Ouedraogo Noufou , Ouedraogo Gueswindé Geoffroy , Ilboudo Sylvain , Ouédraogo Moussa , Ouédraogo Salfo , Assita Lamien-Sanou , Kini Bondo Félix , Guissou Pierre Innocent , Ouédraogo Sylvin
Published: June 2022

In Burkina Faso, sickle cell syndromes affect 8.42% of hospital patients. For the management of sickle cell anemia, a phytomedicine called FACA® capsules based on a mixture of roots barks powdered from Calotropis procera and Zanthozylum zanthozyloïdes has been developed. The objective of this study was to evaluate the acute and sub-chronic toxicity of this mixture. Toxicity studies were conducted according to OECD guidelines on Wistar rats. The acute toxicity test estimated the LD50 to be 5000 mg/kg body weight. The sub-chronic toxicity study showed a significant dose-dependent decrease in food consumption; and the body weight gain of the treated rats. Biochemical analysis showed a significant decrease in the level of serum total protein and cholesterol and an increase of ALT and blood sugar levels at 500 and 1000 mg/kg. A significant decrease in the number of red blood cells and hemoglobin have been observed at 1000 mg/kg. Histopathological examination of the organs shows atrophy of the muscle wall and destruction of the epithelial surface of the stomach at 1000 mg/kg body weight. Based on these results, this mixture does not exhibit acute oral toxicity and could be well tolerated at therapeutic doses (17.5 mg/kg).
Rôle du maraichage dans le développement socioéconomique à l’Office du Périmètre Irrigué de Baguineda
Authors: Samake Moussa , Samake Savio , Keïta Ousmane
Published: June 2022

Le maraîchage est une pratique bien connue en zone rizicole au Mali. Face à une pluviométrie déficitaire entrainant de mauvaises récoltes des céréales, le maraîchage est un espoir pour combler ce déficit et une source de revenus des paysans. Ils fertilisent les parcelles avec des engrais chimiques et organiques, font recours aux pesticides pour combattre les ravageurs. Le but de cette étude était de déterminer le rôle socioéconomique du maraîchage à Baguinéda. Ainsi, une enquête sociodémographique a été conduite auprès des maraîchers à Baguinéda-Camp, Sonougouba et Sébéla. Sous l’égide des points focaux, les questionnaires ont été soumis individuellement à 84 producteurs dont 63 hommes et 21 femmes. Les résultats ont donné 41,7% de maraîchers d’âge inférieure à 36 ans. Parmi les maraîchers, 76 étaient mariés, 5 célibataires 3 veuves. Les intrants employés dans les jardins ont été jugés de mauvaise qualité par 52,0%. Tous utilisaient des pesticides et 35,7% observaient plus de 15 jours entre le dernier traitement et la récolte des légumes. Les revenus générés par la vente des légumes permettent à 88,1% des maraîchers de faire face aux dépenses familiales. En raison de son importance dans la vie socioéconomique, le maraîchage est pratiqué dans la plaine innondable en saison sèche.
Evaluation des risques sanitaires liés à la présence d’af latoxine dans le riz consommé au Sénégal
Authors: Diop Astou Sassoum , Sarr Bathie , Ndong Moussa , Beye Babacar , Fall Ndiaye Mame Arame
Published: June 2022

Les aflatoxines ont été classées comme des agents cancérogènes pour les humains . L’intoxication aux aflatoxines peut ê tre aiguë ou chronique. Au Sénégal deux types de riz sont consommés, le riz lo cal produit dans la vall ée du fleuve et le riz importé d’Asie Les aflatoxines sont susceptibles d’être présentes naturellement dans le riz L’objectif de cette étude était d’évalu e r les risques sanitaires liés à la contaminat i on en aflatoxine du ri z consommé au Sénégal. Pour le riz local, 14 échantillons de 3 variétés ont été prélevés au niveau de 5 sites situ é s dans la vallée du fleuve Sénégal : Baridiam, Ndelle, Ndiaye, Ngomène et Pond Gendarme. Les échantillons des trois types du riz importé ont été prélevés au niveau du grand marché « Sor» de Saint Louis : le riz brisé de la Thaïlande, le riz entier de Chine et le riz entier de Le dosage des aflatoxines B1 et totals du riz local et importé obtenus éta it fait par HPLC suivant la norme ISO 16 050 au Laboratoire de mycotoxine de l’Institut de Technologie Alimentaire (ITA) du Sénégal L’évaluation de l’exposition alimentaire était associée à la concentration moyenne du contaminant, la consommation alimentaire par jour et le poids corpore l de l’individu en kg . Les concentrations en aflatoxines B1, B2 et totale des aflatoxines étaient respectivement de 0,445 μg/kg, 0,064 μg/kg et 0,509 μg/kg pour le riz local. Cette teneur en aflatoxines était de 0,1 μg/kg d’aflatoxines B1 et totale pour le riz importé. Tous ces échantillons de riz local ont eu des teneurs inférieures à 2 μg/kg et 4 μg/kg (seuils respectivement établis par l’Union européenne pour B1 et AFT), et à 20 μg/kg (la norme établie par les Etats Unis et les pays asiatiques). Les valeurs de l’exposition pour le riz importé ont été évaluées à 0,0003 μg/kg pc/j aussi bien pour l’aflatoxine B1 que pour l’AFT. Pour le riz local, l’exposition est estimée à 0,001 μg/kg pc/j pour l’aflatoxine B1 et à 0,002 μg/kg pc/j pour l’AFT. Le ri sque sanitaire lié à la consommation du riz importé ou local est faible pour les aflatoxin e s. Néanmoins, la quantité importante de riz consommée par les sénégalais et la présence d’autres sources potentielles d’aflatoxines dans leur alimentation peuvent au gmenter considérablement le risque.
Assessment of macro and micro elements present in three commonly eaten vegetables in Nigeria
Authors: Adenegan-Alakinde Taiwo Ayomipo , Ojo Funmilola Mabel
Published: June 2022

The study investigated the nutritive elements of four species of Basella and two other commonly eaten vegetables (Amaranthus hybridus and Talinum triangulare). The vegetables are found throughout the year. The mineral compostion of the vegetables was carried out using standard procedures to determine which of these would be of more health benefit to the consumers. Leaves were collected at the initiation of flowering and air-dried under shade for 7 days after which they were kept in an oven at 60oC for 24 hours. These dried materials were mechanically powdered and stored in airtight containers until used for analysis. The phosphorous content of the vegetables ranged from 83.95±0.01 to 136.30±0.01 mg/100g. The potassium content ranged from 733.20±17.7 mg/100g to 4084.20+0.03 mg/100g. Sodium content in the vegetables ranged from 89.25±0.04 to 241.50±0.02 mg/100g. Zinc content ranged from 8.00+2 mg/100g to 28.90+4 mg/100g. The mineral contents of the Basella forms are comparable to Amaranthus hybridus and Talinum triangulare. Overlap observed in the values of the nutrient elements suggests interspecies relationship. Copper was present in Basella rubra and Amaranthus hybridus, while Molybdenum was absent in all. This study revealed that the consumption of these vegetables is dependent on the dietary need of the users.
Methanolic extract of Nauclea diderrichii (stem-bark) show anti-microbial, anti-oxidant and anti-inflammatory bioactivities
Authors: Mensah John Kenneth , Sala Ahmed , Jibira Yakubu
Published: June 2022

The aqueous stem-bark extract of the tropical plant Nauclea diderrichii is used in ethnomedicine to manage symptoms of rheumatism through minimally examined mechanisms. The objective of the study is to examine the scientific bases for the ethnomedicinal use of the plant for the management of rheumatism. As part of this effort to explain its ethnomedicinal efficacy, this study compared and contrasted the anti-microbial, anti-oxidant and anti-inflammatory activities of the methanolic extract with that of the diethylether extract. Broth dilution assay, DPPH radical scavenging assay and carrageenan-induced foot swelling of 7-day old chicks were utilized for the experimental assessment of the bioactivities of Nauclea diderrichii. Polar methanolic extract exhibited a higher antioxidant status in vitro as estimated quantitative differences in total phenolic content, in total antioxidant capacity and in DPPH and H2O2 radical scavenging converged to show the methanolic extract as a more potent anti-oxidant. The methanolic extract also possess better in vivo anti-inflammatory activity as demonstrated by the 1.5-fold lower ED50 relative to that of the diethylether. The methanolic extract demonstrated better broad-spectrum anti-microbial activity against a panel of six clinical isolates of bacterial and fungi pathogens in vitro. The relative strength of the bioactivities of the methanolic extract derives from a higher slew of phytochemical content that is a 3-fold difference larger. The results of this study support the beneficial effect of Nauclea diderrichii in its continuing ethnomedicinal use to target rheumatism chemotherapeutically.
Determinant of the financial structure of manufacturing firms in a developing economy: A study of selected listed manufacturing firms in Nigeria
Authors: Mgbada Friday N. , Nkwede Friday E. , Uguru Leonard C.
Published: June 2022

This study principally interrogates what drives the financial structure of listed firms in an emerging economy, using Nigeria as a paradigm. The study specifically sought to examine the effects of selected major financial variables namely - assets tangibility, profitability and the size of the firms on their financial structure decision. The valid data used in study covered eight selected manufacturing listed firms in the Nigerian Stock Exchange. The study however adopted trade-off theory in the theoretical framework. In the methodology, we employed pooled ordinary least square (POLS) approach. The outcome of the study revealed that size of a firm is a major determinant of financial structure in Nigeria emerging economy for the period under study. From our analysis, p-values of other factors examined such as profitability and asset tangibility showed no significant effect. The study therefore, concluded that high costs of floating shares and bureaucracies in the listing procedures formed some of the challenges faced by these companies while making or adjusting the pattern of their financial structures. The paper recommended that the Nigeria Stock Market should be made operators and investment friendly by reducing the floating costs and effects changes to the stringent listing conditions.
Effect of outsourcing as an emerging work pattern on organizational commitment and performance of employees in selected commercial banks in Owerri Imo State, Nigeria
Authors: Onuoha Justin Ikechukwu
Published: June 2022

This study examined the effect of outsourcing on organizational performance and employee commitment in selected banks in Owerri. Related literature was reviewed and the Force Field Analysis model (FFA) was used as the theoretical framework. The study adopted a descriptive survey research design. Purposive, stratified and simple random techniques were used in selecting the sample. Taro Yammane formula was used to determine sample size of four hundred from the organizations for the collection of quantitative data and six management staff were purposively selected for the qualitative data. Data generated from the field were analyzed using frequency tables and simple percentages. Results from the study showed that outsourcing positively affected organizational performance. It was also found that employees manifested both affective and continuance commitment despite the emerging work trend and positively affected organizational performance. It was recommended that organizations should limit outsourcing while enhancing capacity building through constant training, build more of affective commitment, improve on leadership quality and style and improve general workplace environment to retain commitment and constantly improve on performance, set clear goals and communicate same to employees in an era that experiences change of business strategies to enhance performance.
Economic and Financial Crimes Commission’s (EFCC) performance in combating corruption in Nigeria: Buhari’s administration in perspective (2015-2020)
Authors: Edeh Joseph Nwokpoku , Nwokwu Paul Monday , Ugbala Kenneth Igwe
Published: June 2022

Corruption remains a cankerworm that has continued to hinder genuine efforts towards development in Nigeria. Several efforts have been put in place to curb the menace but it still manifests in various forms. This study was carried out to specifically examine the extent to which the Economic and Financial Crimes Commission has reduced money laundering in Buhari’s regime; to find out the extent to which the EFCC has reduced cybercrimes in Buhari’s regime and to assess how the EFCC has reduced the incidences of embezzlement of public funds in Buhari’s administration. The study was anchored on Deterrence theory espoused by Cesare Beccaria in 1764. The study adopted content analytical technique to analyze data for the study. The study revealed the following among others: that the EFCC has not significantly reduced money laundering in Buhari’s regime; that the EFCC has demonstrated commitments towards reducing cybercrimes in this regime and that the EFCC has not significantly reduced incidences of embezzlement of public fund in Buhari’s regime. The study concluded that development will continue to elude our country as long as corruption continues to ravage the polity. The study therefore, recommended among others that the operatives of the EFCC should always carry out thorough investigations in order to win more cases of money laundering.
Insectary maintenance of Anopheles gambiae (Dipteran, Culicidae): First instar (L1) larvae depicts the accuracy of a pyrethroid insecticide, for malaria control
Authors: Okoh F.N. , Odikamnoro O.O. , Nzei J.I.
Published: June 2022

Malaria is a tropical disease responsible for the death of hundreds of children daily. Effort geared at eliminating the vector that transmit the causative agent are likely to reduce the incidence of malaria and consequent deaths. This study aims to identify the life cycle stage of Anopheles gambiae most susceptible to the insecticide, lambdacyhalothrin. Different life stages of A. gambiae were exposed to six different concentrations of the insecticide in an Insectary at the National Arbor-virus and Vectors Research Centre, Enugu, Southeastern Nigeria. A total of 650 each, of the different life stages and 350 adults selected from the insectary-bred strains were used for the study. The eggs mortality was monitored at 24 hours interval for 7days. Larvae, pupae and adult mortalities were measured after 6, 12 and 24 hours. Total survival and mortality rates were 6.17 and 0.83, respectively. Average developmental duration was 11.4 and 11.2 days for the parent and F1 generations, respectively. Lambdacyhalothrin concentration higher than 0.001mg/l was highly toxic to the different life stages of A. gambiae compared to the control. The first instar larvae (L1) stage was the most susceptible to the insecticide and should be considered the most effective target when planning malaria control interventions.
Guía de actividades lúdicas para el desarrollo socioafectivo en estudiantes de inicial II: Una propuesta educativa
Authors: Loor Zambrano Marjorie Roberta , Tarazona Meza Anicia Katherine
Published: June 2022

El desarrollo socioafectivo es sustancial para el desarrollo humano y es en la etapa infantil donde da inicio. La educación inicial ecuatoriana concibe esta dimensión desde lo curricular en componentes (ejes de desarrollo, ámbitos y objetivos de aprendizaje) en un continuo desde los 0 años hasta los 5. Los 29 estudiantes del subnivel de educación inicial II (4 años) de la Escuela de Educación Básica Club Rotario Portoviejo (Manabí) muestran necesidades de regulación emocional, capacidad empática, expresión emocional y comprensión emocional, por lo que fueron asumidos como rincones de la metodología juego trabajo. El diseño de la guía se hizo a través de las fases de planificación, desarrollo y evaluación.  La guía como propuesta educativa contempló los componentes curriculares, secuencia didáctica y estrategias de enseñanza centradas en el juego complementado con la lectura diaria y la integración de TIC y de la familia en las experiencias de aprendizaje.
Herramientas digitales y el rendimiento académico de los estudiantes de cuarto año básico de la Unidad Educativa Fiscomisional Sathya Sai en la Institución “Teresa Intriago Delgado
Authors: Castro Delgado Angélica María , Cedeño-Palma Emilio Antonio
Published: June 2022

Esta investigación se realizó en la Unidad Educativa Fiscomisional Sathya Sai. El objetivo de este trabajo de investigación fue implementar herramientas digitales para mejorar el rendimiento académico de los estudiantes de cuarto año básico de la Unidad Educativa Fiscomisional Sathya Sai. Pot tal motivo el tipo de investigación es de paradigma positivista con un enfoque cuantitativo de diseño no experimental y correlacional. La Población está definida por 32 estudiantes pertenecientes al cuarto grado de la Unidad Educativa Fiscomisional Sathya Sai.  Por ser un grupo finito se tomó a la población, para la obtención de la información se utilizó la técnica de la encuesta.  El instrumento fue un cuestionario de  preguntas,  por medio del cual se obtiene como principal resultado que el uso de herramientas digitales en las clases originó el aumento del rendimiento académico de los estudiantes de cuarto grado, realizando una comparativa de los promedios del cursos de los años lectivos 2020-2021 y 2021-2022, con un claro mejoramiento del promedio,  por tanto se concluye que el uso de las herramientas digitales en las aulas afecta de forma significativa al rendimiento de los estudiantes
Educación inclusiva y el desarrollo de competencias emocionales en los estudiantes
Authors: Rodríguez Cárdenas Oscar Iván , Quishpe Loor Alejandra Elizabeth , Anchundia Loor Marjorie Alexandra , Mendoza Cevallos Ermita Catalina , Almeida Campuzano Anthony Xavier
Published: June 2022

El impulsar la inclusión en las aulas de educación inicial hasta la básica a partir del fomento del respeto por las diferencias humanas, no ha sido una tarea fácil, pues ello se denota desde la génesis de los anti valores peyorativos familiares y del contexto emocional social excluyente en el cual está sumergido cada estudiante. Este ensayo tiene como propósito, argumentar a partir de la educación inclusiva en la que el desarrollo de la competencia emocional del estudiante es indispensable para transferir en la praxis pedagógica relaciones interpersonales basadas en la comunicación efectiva y el amor a las diferencias humanas. El análisis realizado generó la idea concluyente que una educación inclusiva emocionalmente positiva inculca en todos los estudiantes, la capacidad y voluntad de expresar verazmente sus opiniones y escuchar las de los demás, haciendo posible una comunicación efectiva afectiva, y sin coacciones discriminativas.
La música como estrategia para el desarrollo del lenguaje oral en los estudiantes de 4 años
Authors: Puetate Manitio Gloria Irene , Mendieta Torres Yessica Anabel
Published: June 2022

El presente artículo es producto de una experiencia investigativa la cual  tiene sus bases en un estudio de campo con carácter descriptivo bajo la modalidad de proyecto especial cuyo objetivo fue proponer una guía de estrategias musicales para mediar el desarrollo de lenguaje oral en estudiantes de 4 años de la Unidad Educativa “Baeza. del Cantón Quijos en tal sentido, para la consecución de la propuesta el proceso fue realizado en tres fases: En la Fase I se realizó un estudio diagnóstico el mismo permitió determinar la necesidad de la guía didáctica, para ello se aplicó un instrumento tipo cuestionario y una guía de observación a la docente de la mencionada institución. En función del resultado se prosiguió a la fase II misma que consistió en el diseño de la guía, organizada ésta siguiendo los preceptos curriculares de la Educación Inicial Ecuatoriana. Una vez cumplida esta fase, el diseño fue sometido a validación por expertos en el área cumpliéndose así la fase III. Como conclusión  de este estudio se tiene que es importante que el docente de Educación Inicial este  presto a innovar en  estrategias didáctica para potenciar al niño a un aprendizaje siempre superior, una de esas estrategias es la música dando que inhibe al niño de temores y lo lleva a un escenario natural para que pueda desarrollar su lenguaje oral.
El lenguaje oral como medio fundamental para las relaciones interpersonales en los niños de 5 años
Authors: Pisco Tomalá Carolina Isabel , Antón Vera Gustavo Enrique
Published: June 2022

El desarrollo del lenguaje oral ha sido desatendido de la enseñanza tradicional de la lengua; aún más el hecho de comprender cómo este es el medio para las relaciones interpersonales, pero el enfoque comunicativo permite no solo otorgar primacía a una didáctica de la lengua oral en el aula, sino que facilita el desarrollo de la interacción e integración social. En el Primer Año (1A) de Básica de la Unidad Educativa “Mariscal de Ayacucho” del Cantón Santa Ana – Parroquia Ayacucho (2021-2022) se detectaron (en enfoque cualitativo, método estudio de caso) necesidades de desarrollo del lenguaje oral para las relaciones interpersonales en estudiantes de 5 años. Para atender la necesidad se diseñó un proyecto de aprendizaje, bajo el enfoque de currículo integrador, con 9 estrategias didácticas que permiten demostrar que el asunto del lenguaje oral para las relaciones interpersonales es inherente a todas las áreas de aprendizaje en el currículo ecuatoriano.
Estrategia didáctica para el desarrollo lingüístico de los niños de 4 años de la Unidad Educativa Fiscal “El Palmar”
Authors: Bravo Palacios Melva Clementina , Ginebra Usra Ricardo
Published: June 2022

Este artículo reporta los resultados de un estudio que tuvo como propósito el diseño de una estrategia didáctica basada en la lectoescritura que permita el desarrollo lingüístico de los niños y niñas de la Unidad Educativa Fiscal “El Palmar” en edad promedio de 4 años. Los referentes teóricos están determinados por Colonna (2002) sobre la conducta lingüística de los niños y niñas y la necesidad de conocer las características del lenguaje del niño de 4 años. Metodológicamente, la investigación se enmarcó en un enfoque cuantitativo a través de la recolección de datos y su respectivo análisis y el enfoque cualitativo, bajo el paradigma científico con un diseño de investigación acción participativa fundamentado en las fases citadas por Berrocal, Esposito (2011).  El grupo objeto de estudio estuvo conformado por  ciento trece (113) niños y niñas y cuatro (04) docentes, la directora y ciento ocho (108) padres y madres. Las técnicas de recolección de datos son la observación participante, además, de entrevista semiestructurada que se aplicó a la Directora del centro junto con cuestionarios a los padres y madres de la institución. Los resultados alcanzados demuestran que la aplicación de la estrategia didáctica, contribuyó significativamente en la mejora y desarrollo lingüístico de los niños y niñas del centro educativo objeto de estudio.
Estrategia didáctica para mejorar la expresión oral en los niños y niñas del nivel preescolar
Authors: Lucas López María Elena , Cedeño Letty Aracely
Published: June 2022

La investigación que sintetiza este artículo tuvo como objetivo diseñar una estrategia didáctica basada en el diálogo y la narración para mejorar la expresión oral en niñas y niños del nivel preescolar de la Escuela de Educación Fiscal Básica “Dr. Rómulo Romeo Santana Delgado”. Metodológicamente, la investigación se enmarcó en un enfoque cualitativo, con un diseño de investigación acción participativa con base en los principios de Elliot, a través de la acción metódica de comprensión, planeación e implementación. El grupo de estudio fue de veinticinco (25) niños, niñas y una (01) docente de la etapa inicial. Las técnicas de recolección de datos fueron la observación participante y la entrevista no estructurada aplicada a docentes de la institución. Los resultados de la fase de comprensión develan debilidades en la expresión oral de los niños en relación con el léxico, la verbalización, tono de voz y congruencia de ideas; además, se evidenció un marcado miedo escénico al interactuar en el aula. Durante la planeación se reflexionó colectivamente sobre el valor didáctico del dialogo y la narración para la promoción del lenguaje oral, lo que se comprobó con la aplicación de la estrategia. Se concluye que los niños presentaron cierto nivel de retraso en la adquisición de destrezas para la oratoria y que existen fallas en el proceso de socialización de los párvulos tanto en el hogar como en la escuela. Finalmente, se corroboró en la fase de implementación la efectividad de la estrategia y actividades planificadas.
Técnicas psicoeducativas para el desarrollo de la resiliencia en la formación universitaria
Authors: Anicia Katherine Tarazona Meza Anicia Katherine Tarazona Meza , Mero Delgado Laura Jessenia , Chinga Basurto Kerly Isamar , Avellán Vélez Ligia Patricia
Published: June 2022

El ensayo tiene el propósito de disertar sobre las técnicas psicoeducativas que pueden significar una ayuda para el desarrollo y fortalecimiento de la resiliencia entre los estudiantes universitarios que han vivenciados situaciones traumáticas ante el cambio en la cotidianidad de sus vidas. Se parte del planteamiento que el ingreso y desarrollo en la vida universitaria puede representar el escenario para desarrollar una personalidad resiliente, en función de los nuevos desafíos que deben ser sobrellevados por los estudiantes. Los estudiantes universitarios se enfrentan al ingresar y avanzar en el contexto universitario a diferentes situaciones que generan crisis de identidad, inestabilidad emocional, riesgos de malos hábitos o afectaciones en la salud física. Se ofrecen algunas estrategias que la psicoeducación puede implementar para potenciar la resiliencia en la formación universitaria, en la modalidades informativa y conductual. Se concluye que la psicoeducación representa una estrategia de excepción utilidad al fomentar la resiliencia en los estudiantes universitarios durante su desarrollo formativo académico, en tanto instrumentaliza acciones informativas y psiconductuales para posibilitar y fomentar  habilidades de resiliencia académica.
Research on the Effects of Software Reuse in Project Development
Authors: Devadatta Gawade Sujeet , Patil Harshali
Published: June 2022

Software reuse is the process of reusing software resources. In a new application, all stages of the software development process. Given the high cost and difficulty of building high-quality software, the idea of leveraging earlier software investments is intriguing; yet, software reuse has not shown to be as effective as anticipated and is not widely or systematically adopted in business.
An Overview of Monkeypox Virus and Other Medically Important Poxviruses
Authors: Şahiner Fatih , Tekin Kemal
Published: June 2022

Since the earliest times of history, smallpox left deep traces in the memory of humanity with the great epidemics and destruction (deaths) it caused. Variola virus, which is the causative agent of smallpox, and some other viruses in the same family have been a part of many extraordinary changes in the field of science and medicine. Poxviruses have a privileged position in the scientific world due to the fact that the first examples of immunization (variolation) in ancient civilizations, the first safe vaccines developed for use in humans (cowpox virus, vaccinia virus), first infection model of viral pathogenesis (ectromelia virus), and the first human infection eradicated globally (smallpox). Smallpox virus (variola major) is classified as a biological warfare agent (category A), causing high-mortality infections and epidemics, and remains a worldwide concern. These viruses are also unique with their various biological features. Poxviruses, one of the largest viruses associated with human infections, are widely used as a convenient model in vaccine development and vector-based treatment studies, with large number of protein coding, ability to replicate primarily in the cell cytoplasm (unlike other DNA viruses), and their other advantageous features. More than 10 species of poxviruses cause infections in humans, and except for a few species that are only isolated from humans, these viruses are generally associated with zoonotic infections. Monkeypox virus (MPXV), one of these species, was regarded far from being a threat to humanity in the past due to possible cross-immunity caused by smallpox vaccine. However, local monkeypox cases reported in Central and West Africa in the early 1970s were replaced by small-scale outbreaks in the United States and Sudan in the 2000s, and in the following periods, this virus is considered to be the most important species of the Poxviridae family after the eradication of smallpox virus due to the increasing number of case reports in African countries, especially in the Democratic Republic of Congo and Nigeria. In addition to epidemiological changes that increase the risk of contact with animal reservoirs, the growing proportion of the unvaccinated population and the new and unexpected transmission pattern indicate that human monkeypox infections may continue to intensify. In recent days, while many countries and health authorities have been re-evaluating the existing and potential risks related to monkeypox virus and smallpox virus, some countries have started to take various measures against the possibility of epidemic and biosecurity risks. The main purpose of this article is to consider the general biological characteristics of poxvirus strains, to examine their host distribution, and to provide an overview of the risks attributed to poxvirus strains associated with human infections.
BIOECOLOGIA DO ACARÁ-BANDEIRA Pterophyllum scalare (SCHULTZE IN LICHTENSTEIN, 1823)
Authors: Silva-Júnior Felipe , Sena Raimunda , Oliveira Yasmin , Chagas Rafael
Published: June 2022

The objective of the present work is to present the bioecological characteristics of the angelfish Pterophyllum scalare (Schultze in Lichtenstein, 1823) from a bibliographic review carried out through the search portals in CAPES Periodicals, Google Scholar, Scielo and ScienceDirect, using the scientific and common names of the species as keywords. After the selection and reading of the articles, the taxonomy, biology, ecology, fisheries and conservation status of the species were characterized. The angelfish is a freshwater fish from the Amazon basin that has great commercial importance, acquired mainly due to its exuberance (morphology and color) and for adapting very well to other species. It is an omnivorous fish, which inhabits bentho-pelagic environments, being easily found in rivers and streams with a high density of vegetation. It has a small size, reaching up to 15 cm in standard length. It presents several varieties of coloration commercialized in Brazil and in the world. It is a species that is not at risk of extinction, and its fishing and trade is permitted in accordance with current legislation. The angelfish is widely studied, but there is a gap regarding aspects of fishing.
RISK-INFORMED METHOD FOR PREDICTING THE OPERATION LIFE EXTENSION PERIOD OF ACTIVE SAFETY SYSTEMS AT NUCLEAR POWER PLANTS
Authors: Skalozubov V.I. , Vierinov A.M. , Kosenko S.I. , Alali M. , Kochnyeva V.Yu.
Published: June 2022

An original method has been developed for predicting the operation life extension period of thermal mechanical equipment of safety systems based on the assessment of the residual resource by the number of thermohydrodynamic and mechanical cyclic loads and the test frequency during design operation life. Based on the developed method, as well as the results of technical inspection of pump and armature bodies of emergency core cooling and steam generator emergency feedwater systems, it was found that the permissible operation life extension period is 4 years for the design test frequency, 8 years if the test frequency is reduced by 2 times, 16 years if the test frequency is reduced by 6 times, 20 years if the test frequency is reduced by 10 times. However, the possibility of reducing the test frequency requires additional substantiation for optimizing the test frequency, taking into account the effects of equipment wear and the accumulation of critical defects between tests. The need to optimize the test frequency de-termines the relevance of further research.