bluuebunny/crossref_metadata_2025 huggingface dataset:
EFICIÊNCIA REPRODUTIVA DE REBANHOS LEITEIROS DA RAÇA JERSEY ORIUNDOS DA AGRICULTURA FAMILIAR DO MUNICÍPIO DE REALEZA-PR
Authors: Porto Yuri Da Fontoura , Jaguszeski Mônica Zuchelli , Pinto-Neto Adalgiza , Mota Marcelo Falci , Skonieski Fernando , Merlini Luiz Sérgio , Berber Rodolfo
Published: August 2017

A produção de leite na Região do Sudoeste do Paraná teve desenvolvimento notável nos últimos anos, tornando esta região uma importante bacia leiteira na produção estadual e nacional, sendo que a maior parte desta produção é proveniente de rebanhos que fazem parte da produção familiar. O presente trabalho tem como objetivo avaliar a eficiência reprodutiva de bovinos da Raça Jersey oriundos de rebanhos leiteiros de produção familiar, do Município de Realeza-PR. Para tanto, identificou-se no Município de Realeza-PR, um único rebanho bovino da Raça Jersey pura, desconsiderando aqueles com animais oriundos de cruzamentos com essa raça. Dessa forma, analisou-se a eficiência reprodutiva (ER) desse rebanho, contendo 33 vacas Jersey Puras de Origem, em lactação. A idade e o peso das fêmeas estudadas foi de 4,39 ± 2,04 anos e 402,58 ± 49,56 quilos, respectivamente. Cada fêmea pariu 2,52 ± 1,8 vezes, sendo a idade ao primeiro parto de 2,19 ± 0,57 anos. Os animais apresentaram intervalo de partos de 377 dias, número médio de serviços concepção de 1,77 e período médio de serviço de 105 dias. Considerando todo período reprodutivo útil das fêmeas estudadas, que variou de uma a dez concepções seguidas de gestação, 61% delas ficaram gestantes na primeira IA. A taxa de natalidade do rebanho durante o período de estudo foi de 90,9%, sendo considerada adequada, e a de aborto/natimortos de 10%. Observou-se viabilidade produtiva e reprodutiva para a produção de leite a partir do rebanho estudado.
COBRE E SEU USO NA DIETA DE FRANGOS DE CORTE (Gallus gallus) REVISÃO DE LITERATURA
Authors: Silveira Alysson Polzonoff , Otutumi Luciana Kazue , Dourado Maíra Rodrigues , Paschoal Eliane Cuaglio , Amaral Patrícia Franco Gonçalves Previato do , Michelin Amanda Caroline , Soares Andréia Assunção , Pereira Júnior Jair
Published: August 2017

O cobre é um mineral essencial ao metabolismo e seu uso tem sido associado à melhora do desempenho zootécnico, aumento da resistência ao estresse e doença nas aves. A indústria avícola com o intuito de maximizar o desempenho produtivo formula normalmente as dietas com altas doses da fonte inorgânica de cobre, o que contribui para o desequilíbrio metabólico e como consequência aumenta a poluição ao meio ambiente. Dessa forma, o uso de fontes orgânicas de cobre tem sido estimulado. Sendo assim, o objetivo do presente trabalho foi revisar a utilização do cobre na dieta de frangos de corte com enfoque para os benefícios das fontes orgânicas. Conclui-se que fontes mais biodisponíveis de cobre são uma oportunidade para diminuir sua inclusão, mantendo o desempenho do animal, por meio da redução de agentes patogênicos, melhora na digestibilidade e redução ao impacto ambiental em dietas de frango de corte.
Governance of Journalism and Alternatives to the Crisis
Authors: Mick Jacques , Tavares Luísa
Published: August 2017

The article supports the hypothesis that contemporary journalism is facing a crisis of governance, derived from the fraying of social relations between the media enterprises and their audiences (readers, sources, stakeholders, advertisers, subscribers). In contrast to the interpretations that limit the crisis to the funding issue or the business model, we argue that such difficulties are apparent manifestations of structural changes in relations between journalism and the public, affecting both production and circulation of journalistic information processes, particularly concerning its corporate organizational form. Each of these dimensions is affected by actions and representations of the audiences, heavily modified in just over a decade in response to the changes in technology and communication. The article demonstrates how the concept of governance gives a better understanding of the dimensions of the crisis and a glimpse into the possible solutions.O artigo sustenta a hipótese de que o jornalismo contemporâneo atravessa uma crise em sua governança, derivada do esgarçamento das relações sociais entre as empresas jornalísticas e seus públicos (audiências, fontes, stakeholders, anunciantes, assinantes). Contra as interpretações da crise que a circunscrevem ao financiamento ou ao modelo de negócio, argumenta-se que tais dificuldades são manifestações aparentes de transformações estruturais nas relações com os públicos, que afetam tanto os processos de produção e circulação da informação jornalística, quanto sua forma organizacional predominantemente empresarial. Sobre cada uma dessas dimensões incidem ações e representações dos públicos, fortemente modificadas num intervalo de pouco mais de uma década como reação às transformações tecnológicas e de comunicação. O artigo demonstra como o conceito de governança permite compreender melhor as dimensões da crise e vislumbrar possibilidades de saída.Este artículo sostiene la hipótesis de que el periodismo contemporáneo está pasando por una crisis de gobernabilidad, derivada del deshilachado de las relaciones sociales entre los medios y sus audiencias (los lectores, las fuentes, los stakeholders, los anunciantes, los abonados). Contra las interpretaciones que circunscriben la crisis a la financiación o al modelo de negocio, se argumenta que tales dificultades son manifestaciones estructurales de cambios profundos en las relaciones con el público, que afectan tanto a los procesos de producción y circulación de la información periodística, como su forma organizacional de negocio. Las acciones y representaciones del público, muy cambiadas en un intervalo de poco más de una década en respuesta a los cambios tecnológicos y de la comunicación, afectan cada una de esas dimensiones. El presente artículo muestra cómo el concepto de gobernabilidad permite comprender mejor las dimensiones de la crisis e imaginar las posibilidades de salida.
Alterity, Otherness and Journalism: From Phenomenology to Narration of Modes of Existence
Authors: Freitas Camila , Benetti Marcia
Published: August 2017

In a theoretical reflection, the aim of this paper is primarily to discuss alterity in journalism. We believe that journalism plays a fundamental role in the construction of knowledge on similarities and differences between human beings, stressing social diversity as one of its purposes. We associate the concept of otherness, understood as a singular mode of existence of the “other”, with the purpose of journalism and with actions of empathy, sympathy and compassion. Based on a phenomenological perspective, we discuss the importance of the meeting between the "self" and the "other", as well as the ability of journalists to perceive and narrate on the aspects that shape the identities of human beings. Moreover, we discuss otherness in journalistic narratives, approaching the relation between the lifeworld and the world of text, taking into consideration the elements of perception, mimesis, textuality and interpretation.Este artigo tem caráter teórico e visa discutir a alteridade no jornalismo. Consideramos que o jornalismo tem um papel fundamental na construção do conhecimento sobre as semelhanças e as diferenças entre os seres humanos, sendo a apresentação da diversidade social uma de suas finalidades. Propomos associar o conceito de outridade, compreendida como o modo de existência do “outro” em sua singularidade, a essa finalidade do jornalismo e a ações de empatia, simpatia e compaixão. Adotamos uma perspectiva fenomenológica, indicando a relevância da experiência do encontro entre o “eu” e o “outro” e a capacidade de o jornalista perceber e narrar os aspectos que configuram as múltiplas identidades dos seres. Tratamos ainda da outridade na narrativa jornalística, abordando a relação entre o mundo da vida e o mundo do texto e discutindo os princípios da percepção, da ação mimética, da textualidade e da interpretação. Este artículo de carácter teórico analiza la alteridad en el periodismo. Creemos que el periodismo tiene un papel fundamental en la construcción de los saberes acerca de las similitudes y diferencias entre los seres humanos, una vez que la presentación de la diversidad social és uno de sus propósitos. Combinamos el concepto de otredad, que se entiende como el modo de existencia del "otro" en su singularidad, con la finalidad del periodismo. Adoptamos un punto de vista fenomenológico, lo que indica la importancia de la experiencia del encuentro entre "yo" y "otro" y la capacidad del periodista para percibir y narrar características de las múltiples identidades de los seres. También trabajamos con la otredad en la narrativa periodista, presentando la relación entre el mundo de la vida y el mundo del texto, así tratando de los principios de la percepción, de la acción mimética, de la textualidad y de la interpretación.
全球金融周期与国际货币政策协调
Authors: 朱 珠
Published: August 2017

通过结合金融市场运行出现的新特征，本文介绍了全球金融周期的定义及其影响因素，并对这一周期运行下的国际货币政策协调提出了建设性意见。研究表明 ：（1）全球金融周期正在逐步形成，国别金融周期正在逐步弱化。（2）核心国家的货币政策对全球金融周期的运行具有主导作用。（3）构建 G20 框架下的多层次国际货币政策协调机制，应该是国际社会今后的努力方向。
施工企业集中核算管理模式研究
Authors: 任 姝奈
Published: August 2017

随着中国市场经济迅猛增长和经济体制的日趋完善，施工企业如雨后春笋般成长起来，其经济实力和规模都达到了一定的水平，与此同时，其资金管理问题已成为制约企业健康持续发展的重要因素。近年来，传统意义上的资金管控手段问题不断，需要运用科学并且合理的方法，建立统一规范、反应迅捷的资金管理体系，从而实现扁平化的资金集中管理。基于此，本文将对当前施工企业集中核算管理模式进行研究，指出其所存在的问题，并提出完善此管理模式的一系列相关措施。
浅析网络环境下的企业管理创新
Authors: 杜 丽昆
Published: August 2017

21 世纪已经步入了信息化的时代，各行各业迈入了“互联网 +”的发展模式中。对于处在激烈的市场竞争中的企业而言，管理水平能够反映一个企业的内部控制水平与竞争实力。但是现今企业正处于经济转型时期，需要尽快从传统的管理模式转变到新型的企业管理模式来，勇于创新，满足市场经济发展的需求以及企业自身发展的需求，这是企业在网络经济环境中抢占市场先机的必然选择与关键途径。
简述企业文化创新对企业管理创新的影响力
Authors: 王 献强
Published: August 2017

在时代发展的大浪潮下，企业必须不断创新才能保持活力。而一个企业的文化创新直接影响和决定着企业管理的创新，因此，企业必须有创新型的企业文化才能带动整个企业的创新。本文探讨企业文化及企业文化创新对企业发展的价值，企业管理创新的价值，并分析企业文化创新对企业管理创新产生的影响力，在此基础上提出企业创新的措施。
从商业伦理视角分析内部人控制现象 ——以中国山水水泥争夺战为例
Authors: 宋 书香
Published: August 2017

伴随着企业所有权与经营权相分离，出现了内部人控制现象，其拥有两面性。当所有者与经营者之间的制衡机制被打破，公司内部人控制行为超越合理范围，就造成了内部人控制问题。造成内部人控制问题的原因很多，本文以中国山水水泥争夺大战为案例，从内部控制人的伦理失范方面探讨内部人控制问题的原因。
基于柔度二次扩展的结构损伤识别方法
Authors: 戴 斌
Published: August 2017

为了提高指标对低阶模态的利用率，引入柔度二次扩展的概念作为一种改进措施，利用扩展后的柔度矩阵代替原有柔度矩阵进行损伤识别。简支梁和连续梁的损伤算例表明 ：引入二次扩展矩阵后能够识别出损伤位置，加强指标对低阶模态的利用率，对工程结构损伤识别有参考价值。
中国河北省民办高职院校教师队伍建设对策分析
Authors: 董 彦霞
Published: August 2017

河北省作为中国高等教育大省，紧邻北京、天津，优质教育资源丰富，为民办高职教育的发展创造了有利条件。近年来，民办高职院校不断扩张，数量也在不断增加，导致民办高职院校教师队伍建设问题日益突出，本文从民办高职院校教师队伍建设存在的问题及对策分析出发，提出了相应的对策和建议。
Desafios da Educação Profissional: por um trabalho pedagógico no Ensino Médio Integrado
Authors: Maraschin Mariglei Severo
Published: August 2017

Como uma das formas de oferta da Educação Profissional, tem-se o Ensino Médio Integrado, sendo esta uma das funções dos Institutos Federais. Reconhece-se, neste sentido, a importância de olhar para essa etapa de formação com o objetivo de ver avanços e ir além. Assim, o objetivo deste texto é tecer uma avaliação dos últimos anos da trajetória da Educação Profissional no Brasil e destacar desafios para o Ensino Médio Integrado, incluindo a Educação de Jovens e Adultos. Acredita-se que é chegada a hora de investir fortemente em um trabalho pedagógico, trabalho este que envolve pessoas para o objetivo do Ensino Médio Integrado: integração e criticidade. O artigo destacará os avanços da Educação Profissional, os desafios e o caminho que se quer chegar. A partir da pesquisa bibliográfica, busca-se trazer problematizações para a melhoria do Ensino Médio Integrado, em especial olhando para os dados do Rio Grande do Sul, a partir de um trabalho pedagógico crítico e integrado. Muitos são os desafios, mas acredita-se na efetivação de uma política de formação integrada como opção para a melhoria do Ensino Médio.
Importância da fibra alimentar na nutrição de animais não ruminantes
Authors: Goulart Fernanda Rodrigues , Adoriam Taida Juliana , Mombach Patrícia Inês , Da Silva Leila Picolli
Published: August 2017

Por muito tempo, a fi bra da dieta representou a porção inerte do alimento em razão do seu baixo teor de energia. Além disso, essa fração também foi considerada como nutriente indesejável na dieta de monogástricos, em razão, principalmente, dos efeitos negativos de sua presença, como seu efeito diluidor de energia. Porém, esses efeitos podem estar relacionados à quantifi caçãoerrônea dessa fração. Quando as fi bras são determinadas de forma correta e adicionadas em quantidades adequadas, os efeitos deste nutriente trazem vários benefícios aos animais. As fi bras alimentares são formadas por polissacarídeos não amiláceos, dentre os quais podemos destacar a celulose, hemicelulose, pectinas, gomas, mucilagens, β-glicanas, entre outras. Frações essasque vêm recebendo grande atenção, devido às suas propriedades prebióticas. A principal ação prebiótica ocorre pela ativação do metabolismo de um grupo de bactérias benéfi cas do trato gastrointestinal, promovendo aumento na produção de ácidos graxos de cadeia curta e do número de vilos no íleo, o que permite aumento na área absortiva intestinal e consequentemente melhora no desempenho animal.
Manejo de irrigação via solo e clima na cultura do milho (Zea mayz L.) na região de Alegrete/RS
Authors: Silva Gideon Ujacov da , Parizi Ana Rita Costenaro , Gomes Ana Carla dos Santos , Pivoto Otávio Gomes , Peccin Marcelo Duarte
Published: August 2017

Na agricultura, o manejo do sistema de irrigação é uma parcela que contribui significativamente para o sucesso do empreendimento. Muitos sistemas são bem dimensionados e apresentam défi cit econômico em função da aplicação inadequada da água, sem consideração dos critérios de solo, planta e atmosfera que indicam o momento e a quantidade ideal da lâmina de irrigação a ser aplicada. O objetivo do presente trabalho foi avaliar o efeito do manejo da irrigação via solo e clima na cultura do milho conduzida na região de Alegrete, RS. O experimento foi desenvolvido em área experimental do Instituto Federal Farroupilha (IF Farroupilha) – Campus de Alegrete/RS e foi constituído de blocos ao acaso com três tratamentos (manejos de irrigação): Sem irrigação suplementar (T0), Irrigação suplementar Via Clima (T1) e Irrigação suplementar Via Solo (T2), comtrês repetições constituídas de 54 linhas de 24 metros. A semeadura da cultura foi realizada no mês de outubro de 2015 sob sistema de plantio direto. Foi utilizado um sistema de irrigação do tipo aspersão convencional. Durante o ciclo da cultura, foram realizadas determinações de área foliar, altura de plantas e diâmetro de caule. Ao fi nal do ciclo da cultura, determinaram-se variáveis de componentes de cultura, produção de grãos e matéria seca. Para interpretação dos resultados, foiutilizado o programa estatístico Assistat 7.0 beta. Os resultados obtidos demonstraram que ocorreu diferença estatística na variável produção de matéria seca para os tratamentos irrigados. A produção de grãos e os componentes de produção não diferiram estatisticamente, porém apresentaram um aumento expressivo nas variáveis analisadas. O tratamento T1 apresentou produção de grãos de 13,5% superior ao tratamento T2 e 28,2% superior ao T0. Para as condições de clima e solo em que o experimento foi conduzido, o tratamento T1 apresentou melhor desempenho.
Development and Evaluation of Enhanced Airfield Signage for Temporary Information
Authors: Le Bris Gaël
Published: August 2017

The aviation community has faced several accidents and incidents on infrastructures and procedures temporarily modified for the purpose of construction works. The analysis of these events shows that usual means of communication to the air crews are the weak link of the safety chain. To address the key challenge of situational awareness during construction works, the Airport Construction Advisory Council of FAA and Paris–Charles de Gaulle Airport (Paris-CDG) developed and evaluated with the airfield community, from 2011 to 2016, an innovative aviation signage. Parallel and complementary studies in human factors led to the definition of specifications for a temporary information signage, also called orange construction sign. Paris-CDG focused on the development of specific messages for each one of the major hazards that could require an increased situational awareness of the air crews during taxiing and takeoff. The results of the evaluation conducted by FAA were published in September 2015. The purpose of this paper is to present the parallel study performed by the author at Paris-CDG with the coalition of the airside operations stakeholders. Both research projects are convergent and confirm the relevance of the orange sign concept for increasing the situational awareness and preventing safety events during airfield construction.
Management urbaner Wälder zwischen Ansprüchen der Gesellschaft und Besitzerzielen
Authors: Lupp Gerd , Börtitz Katharina , Kantelberg Valerie , Koch Marc , Pauleit Stephan
Published: August 2017

Management of urban woodlands between demands of society and owner objectives

Urban woodlands provide numerous ecosystem services for the society. However, they depend on the management goals, motivations and interests of the forest owners. In the Munich Metropolitan Region, it was examined how the population perceive the woodlands and which services of the woodlands are most important for them. On the other hand management goals, interests and motivation of forest owners were assessed by interviewing representatives of state, communal and private forest owners in urban area. It turned out that both population and forest owners had quite similar ideas about the services urban woodlands should deliver. For many forest owners, timber production was of little importance. The main objective was creating and maintaining stable and ecologically valuable mixed stands. In the everyday perception of the population, there is a deep fear of losing woodlands for urban development. Forest management actions are often associated with a general loss of forest. To avoid conflicts, communication and information should be improved. To provide attractive forest consultancy for urban woodland owners, forest authorities and forest associations should include topics such as forest aesthetics, nature conservation, pest control, legal duty to maintain safety, recreation and visitor management.
A Teleological Approach to the Wicked Problem of Managing Utría National Park
Authors: García Nicolás Acosta , Farrell Katharine N. , Heikkinen Hannu I. , Sarkki Simo
Published: August 2017

Utría National Park is a remote biodiversity hotspot in Colombia. It encompasses ancestral territories of the Embera indigenous peoples and borders territories of Afro-descendant communities in El Valle. We explore environmental value conflicts regarding the use of the park, describing them as a Wicked Problem that has no clear solution. Juxtaposing how the territory is perceived by different communities, we employ Faber et al.'s heuristic of the three tele of living nature to search for deficiency in the third telos, service, which we take to be symptomatic of Wicked Problems. Based on field data encoded using the three-tele heuristic, concerning how the respective communities would like to use the park area, we identify deficiencies in the third telos and develop recommendations regarding how these might be addressed.
Nonhuman Animals as Property Holders: An Exploration of the Lockean Labour-Mixing Account
Authors: Milburn Josh
Published: August 2017

Recent proposals in political philosophy concerning nonhuman animals as property-holders – by John Hadley and Steve Cooke – have focused on the interests that nonhuman animals have in access to and use of their territories. The possibility that such rights might be grounded on the basis of a Lockean (that is, labour-mixing) account of property has been rejected. In this paper, I explore four criticisms of Lockean property rights for nonhuman animals – concerning self-ownership, initiative, exertion and the sufficiency of protection offered – concluding that Lockean property rights could be extended to nonhuman animals. I then suggest that Lockean property rights actually offer advantages over interest-based accounts: they more clearly ground property, they are potentially broader, and they are considerably stronger.
A Case Report of Rhabdomyosarcoma of Uterine Cervix in a 7-Month-Old Child
Authors: Yasmin Farzana , Ahmed Md Ashraf Uddin , Begum Tahmina , Ahmed Tasnima , Baki Md Abdul
Published: August 2017

Rhabdomyosarcoma is the soft tissue tumor derived from embryonic primary mesenchyme. Neck, head and genitourinary region are the common locations of rhabdomyosarcoma. Here, we report a 7-month-old child who presented with a protruding mass per vaginally. Abdominal examination revealed a 6 cm x 6 cm hard, irregular, non-tender mass at pelvic region. Ultrasound of abdomen showed large heterogenous pelvic mass of uterine origin. Magnetic resonance imaging of whole abdomen revealed an intrapelvic teratoma (9.5 x 7.4 x 10 cm3) with left sided hydronephrotic change as the mass was pressing the rectum and bladder. The child underwent a total hysterectomy. Histopathology result was suggestive of rahbdomyosarcoma of uterus.Birdem Med J 2017; 7(3): 242-244
Nature and Location of Carbonaceous Species in a Composite HZSM-5 Zeolite Catalyst during the Conversion of Dimethyl Ether into Light Olefins
Authors: Ibáñez María , Pérez-Uriarte Paula , Sánchez-Contador Miguel , Cordero-Lanzac Tomás , Aguayo Andrés , Bilbao Javier , Castaño Pedro
Published: August 2017

The deactivation of a composite catalyst based on HZSM-5 zeolite (agglomerated in a matrix using boehmite as a binder) has been studied during the transformation of dimethyl ether into light olefins. The location of the trapped/retained species (on the zeolite or on the matrix) has been analyzed by comparing the properties of the fresh and deactivated catalyst after runs at different temperatures, while the nature of those species has been studied using different spectroscopic and thermogravimetric techniques. The reaction occurs on the strongest acid sites of the zeolite micropores through olefins and alkyl-benzenes as intermediates. These species also condensate into bulkier structures (polyaromatics named as coke), particularly at higher temperatures and within the meso- and macropores of the matrix. The critical roles of the matrix and water in the reaction medium have been proved: both attenuating the effect of coke deposition.
LPE Growth of Single Crystalline Film Scintillators Based on Ce3+ Doped Tb3−xGdxAl5−yGayO12 Mixed Garnets
Authors: Gorbenko Vitalii , Zorenko Tetiana , Witkiewicz Sandra , Paprocki Kazimierz , Sidletskiy Oleg , Fedorov Alexander , Bilski Paweł , Twardak Anna , Zorenko Yuriy
Published: August 2017

The growth of single crystalline films (SCFs) with excellent scintillation properties based on the Tb1.5Gd1.5Al5−yGayO12:Ce mixed garnet at y = 2–3.85 by Liquid Phase Epitaxy (LPE) method onto Gd3Al2.5Ga2.5O12 (GAGG) substrates from BaO based flux is reported in this work. We have found that the best scintillation properties are shown by Tb1.5Gd1.5Al3Ga2O12:Ce SCFs. These SCFs possess the highest light yield (LY) ever obtained in our group for LPE grown garnet SCF scintillators exceeding by at least 10% the LY of previously reported Lu1.5Gd1.5Al2.75Ga2.25O12:Ce and Gd3Al2–2.75 Ga3–2.25O12:Ce SCF scintillators, grown from BaO based flux. Under α-particles excitation, the Tb1.5Gd1.5 Al3Ga2O12:Ce SCF show LY comparable with that of high-quality Gd3Al2.5Ga2.5O12:Ce single crystal (SC) scintillator with the LY above 10,000 photons/MeV but faster (at least by 2 times) scintillation decay times t1/e and t1/20 of 230 and 730 ns, respectively. The LY of Tb1.5Gd1.5Al2.5Ga2.5O12:Ce SCFs, grown from PbO flux, is comparable with the LY of their counterparts grown from BaO flux, but these SCFs possess slightly slower scintillation response with decay times t1/e and t1/20 of 330 and 990 ns, respectively. Taking into account that the SCFs of the Tb1.5Gd1.5Al3–2.25Ga2–2.75O12:Ce garnet can also be grown onto Ce3+ doped GAGG substrates, the LPE method can also be used for the creation of the hybrid film-substrate scintillators for simultaneous registration of the different components of ionization fluxes.
Interconnecting Microgrids via the Energy Router with Smart Energy Management
Authors: Liu Yingshu , Fang Yue , Li Jun
Published: August 2017

A novel and flexible interconnecting framework for microgrids and corresponding energy management strategies are presented, in response to the situation of increasing renewable-energy penetration and the need to alleviate dependency on energy storage equipment. The key idea is to establish complementary energy exchange between adjacent microgrids through a multiport electrical energy router, according to the consideration that adjacent microgrids may differ substantially in terms of their patterns of energy production and consumption, which can be utilized to compensate for each other’s instant energy deficit. Based on multiport bidirectional voltage source converters (VSCs) and a shared direct current (DC) power line, the energy router serves as an energy hub, and enables flexible energy flow among the adjacent microgrids and the main grid. The analytical model is established for the whole system, including the energy router, the interconnected microgrids and the main grid. Various operational modes of the interconnected microgrids, facilitated by the energy router, are analyzed, and the corresponding control strategies are developed. Simulations are carried out on the Matlab/Simulink platform, and the results have demonstrated the validity and reliability of the idea for microgrid interconnection as well as the corresponding control strategies for flexible energy flow.
Overview of AC Microgrid Controls with Inverter-Interfaced Generations
Authors: Hossain Md , Pota Hemanshu , Issa Walid , Hossain Md
Published: August 2017

Distributed generation (DG) is one of the key components of the emerging microgrid concept that enables renewable energy integration in a distribution network. In DG unit operation, inverters play a vital role in interfacing energy sources with the grid utility. An effective interfacing can successfully be accomplished by operating inverters with effective control techniques. This paper reviews and categorises different control methods (voltage and primary) for improving microgrid power quality, stability and power sharing approaches. In addition, the specific characteristics of microgrids are summarised to distinguish from distribution network control. Moreover, various control approaches including inner-loop controls and primary controls are compared according to their relative advantages and disadvantages. Finally, future research trends for microgrid control are discussed pointing out the research opportunities. This review paper will be a good basis for researchers working in microgrids and for industry to implement the ongoing research improvement in real systems.
Production of Bio-Derived Fuels and Chemicals
Authors: Ezeji Thaddeus
Published: August 2017

The great demand for, and impending depletion of petroleum reserves, the associated impact of fossil fuel consumption on the environment, and volatility in the energy market have elicited extensive research on alternative sources of traditional petroleum-derived products such as biofuels and bio-chemicals.[...]
Intrachromosomal Rearrangements in Rodents from the Perspective of Comparative Region-Specific Painting
Authors: Romanenko Svetlana , Serdyukova Natalya , Perelman Polina , Pavlova Svetlana , Bulatova Nina , Golenishchev Feodor , Stanyon Roscoe , Graphodatsky Alexander
Published: August 2017

It has long been hypothesized that chromosomal rearrangements play a central role in different evolutionary processes, particularly in speciation and adaptation. Interchromosomal rearrangements have been extensively mapped using chromosome painting. However, intrachromosomal rearrangements have only been described using molecular cytogenetics in a limited number of mammals, including a few rodent species. This situation is unfortunate because intrachromosomal rearrangements are more abundant than interchromosomal rearrangements and probably contain essential phylogenomic information. Significant progress in the detection of intrachromosomal rearrangement is now possible, due to recent advances in molecular biology and bioinformatics. We investigated the level of intrachromosomal rearrangement in the Arvicolinae subfamily, a species-rich taxon characterized by very high rate of karyotype evolution. We made a set of region specific probes by microdissection for a single syntenic region represented by the p-arm of chromosome 1 of Alexandromys oeconomus, and hybridized the probes onto the chromosomes of four arvicolines (Microtus agrestis, Microtus arvalis, Myodes rutilus, and Dicrostonyx torquatus). These experiments allowed us to show the intrachromosomal rearrangements in the subfamily at a significantly higher level of resolution than previously described. We found a number of paracentric inversions in the karyotypes of M. agrestis and M. rutilus, as well as multiple inversions and a centromere shift in the karyotype of M. arvalis. We propose that during karyotype evolution, arvicolines underwent a significant number of complex intrachromosomal rearrangements that were not previously detected.
Nurse Perceptions of Artists as Collaborators in Interprofessional Care Teams
Authors: Sonke Jill , Pesata Virginia , Lee Jenny , Graham-Pole John
Published: August 2017

Increased attention is being given to interprofessional collaboration in healthcare, which has been shown to improve patient satisfaction, patient safety, healthcare processes, and health outcomes. As the arts and artists are being more widely incorporated into healthcare settings throughout the world, professional artists are contributing to interprofessional care teams. A secondary directed content analysis of interviews with 31 nurses on a medical-surgical care unit investigated the roles and impacts of professional artists on the interprofessional care team. The investigation utilized established domains of interprofessional care, including values and ethics, roles and responsibilities, interprofessional communication, and teams and teamwork, and created the domain of quality of care. Findings suggest that artists are valued by nurses as members of the interprofessional care team, that they enhance the provision of patient-centered care, and that they improve quality of care by providing holistic dimensions of caring, including cognitive and social engagement, and meaningful interaction. The presence of artists on interprofessional teams provides a cost-effective and welcome resource for clinical staff and builds a culture in which creativity and interdisciplinary collaboration are more highly valued and activated.
Poverty and Child Behavioral Problems: The Mediating Role of Parenting and Parental Well-Being
Authors: Kaiser Till , Li Jianghong , Pollmann-Schult Matthias , Song Anne
Published: August 2017

The detrimental impact of poverty on child behavioral problems is well-established, but the mechanisms that explain this relationship are less well-known. Using data from the Families in Germany Study on parents and their children at ages 9–10 (middle childhood), this study extends previous research by examining whether or not and to what extent different parenting styles and parents’ subjective well-being explain the relationship between poverty and child behavior problems. The results show that certain parenting styles, such as psychological control, as well as mothers’ life satisfaction partially mediate the correlation between poverty and child behavioral problems.
SMAD2 Inactivation Inhibits CLDN6 Methylation to Suppress Migration and Invasion of Breast Cancer Cells
Authors: Lu Yan , Wang Liping , Li Hairi , Li Yanru , Ruan Yang , Lin Dongjing , Yang Minlan , Jin Xiangshu , Guo Yantong , Zhang Xiaoli , Quan Chengshi
Published: August 2017

The downregulation of tight junction protein CLDN6 promotes breast cancer cell migration and invasion; however, the exact mechanism underlying CLDN6 downregulation remains unclear. CLDN6 silence is associated with DNA methyltransferase 1 (DNMT1) mediated DNA methylation, and DNMT1 is regulated by the transforming growth factor beta (TGFβ)/SMAD pathway. Therefore, we hypothesized that TGFβ/SMAD pathway, specifically SMAD2, may play a critical role for CLDN6 downregulation through DNA methyltransferase 1 (DNMT1) mediated DNA methylation. To test this hypothesis, we blocked the SMAD2 pathway with SB431542 in two human breast cancer cell lines (MCF-7 and SKBR-3). Our results showed that treatment with SB431542 led to a decrease of DNMT1 expression and the binding activity for CLDN6 promoter. The methylation level of CLDN6 promoter was decreased, and simultaneously CLDN6 protein expression increased. Upregulation of CLDN6 inhibited epithelial to mesenchymal transition (EMT) and reduced the migration and invasion ability of both MCF-7 and SKBR-3 cells. Furthermore, knocked down of CLDN6 abolished SB431542 effects on suppression of EMT associated gene expression and inhibition of migration and invasion. Thus, we demonstrated that the downregulation of CLDN6 is regulated through promoter methylation by DNMT1, which depends on the SMAD2 pathway, and that CLDN6 is a key regulator in the SMAD2/DNMT1/CLDN6 pathway to inhibit EMT, migration and invasion of breast cancer cells.
Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression and Autism-Related Behaviors in Mice
Authors: Shibutani Mihiro , Horii Takuro , Shoji Hirotaka , Morita Sumiyo , Kimura Mika , Terawaki Naomi , Miyakawa Tsuyoshi , Hatada Izuho
Published: August 2017

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with core symptoms that include poor social communication, restricted interests, and repetitive behaviors. Several ASD mouse models exhibit impaired social interaction, anxiety-like behavior, and elevated perseveration. Large-scale whole exome sequencing studies identified many genes putatively associated with ASD. Like chromodomain helicase DNA binding protein 8 (CHD8), the most frequently mutated gene in individuals with ASD, the candidate gene AT-rich interaction domain 1B (ARID1B) encodes a chromatin remodeling factor. Arid1b heterozygous knockout (hKO) mice exhibited ASD-like traits related to social behavior, anxiety, and perseveration, in addition to associated features reported in some cases of ASD, such as reduced weight, impaired motor coordination, and hydrocephalus. Hydrocephalus was present in 5 of 91 hKO mice, while it was not observed in wild-type littermates (0 of 188). Genome-wide gene expression patterns in Arid1b hKO mice were similar to those in ASD patients and Chd8-haploinsufficient mice, an ASD model, and to developmental changes in gene expression in fast-spiking cells in the mouse brain. Our results suggest that Arid1b haploinsufficiency causes ASD-like phenotypes in mice.
The First Results of Extended Newborn Screening in Slovakia—Differences between the Majority and the Roma Ethnic Group
Authors: Dluholucký Svetozár , Knapková Mária
Published: August 2017

The authors present the first results of the National Extended Newborn Screening (ENS) in Slovakia in the majority (M) and the Roma (R) ethnic populations. A follow-up of ethnicity has been introduced in newborn screening for cystic fibrosis (NSCF) and afterwards to the entire ENS program comprising of 23 inborn errors of metabolism (IEM). In 2013–2015, a total of 165,648 newborns were investigated in ENS, 23,321 of them (14%) were the R ethnic group, a total of 313 positive cases were discovered (total ENS prevalence = 1:529, M = 1:758, R = 1:198). In the R ethnic group, there was a slightly higher prevalence of congenital hypothyroidism (CH), only one case of CF, and no cases of congenital adrenal hyperplasia (CAH) in the R ethnic group. The ENS prevalence of IEM detected by MS/MS was significantly higher in the R ethnic group than in M group (M = 1:1670 vs. R = 1:234, OR:7,13). Significant differences in the prevalence of individual types of IEM were also found. While PKU and other aminoaciduria and organic acidurias dominate in the M group, the fatty acid oxidation disorders (MCAD, SCAD) and carnitine defects (CUD) were more frequent in the R newborn group. Despite the preliminary nature of the results, an ethnic approach to ENS enables the recording of the ethnic differences in the screen prevalence of individual disorders, which would not be apparent without this approach.
Influence of Pressure Fluctuations on the Mean Value of Different Pneumatic Probes
Authors: Bauinger Sabine , Marn Andreas , Göttlich Emil , Heitmeir Franz
Published: August 2017

For this study, measurements were carried out in a one-and-a-half stage test turbine. In order to characterize the flow field and to obtain steady flow quantities, five-hole probes are used in the rig in several measurement planes. Although a very high resolution in circumferential and radial direction is possible with five-hole probes, only certain sectors of the flow field can be measured due to quite long measurement times. For this reason, total pressure rakes, which can be traversed 360 degrees in a circumferential direction, were built for this test configuration. During foregoing measurements, differences between the total pressure measured with the rakes and the total pressure measured with a five-hole probes were observed, especially in the measurement plane downstream of the rotor where the flow is highly unsteady. It was found that the measured value for total pressure is particularly influenced by the stochastic pressure fluctuations and turbulence and can therefore deviate significantly from the “real” value.
An Extended VIKOR-Based Approach for Pumped Hydro Energy Storage Plant Site Selection with Heterogeneous Information
Authors: Wu Yunna , Liu Lingyun , Gao Jianwei , Chu Han , Xu Chuanbo
Published: August 2017

The selection of a desirable site for constructing a pumped hydro energy storage plant (PHESP) plays a vital important role in the whole life cycle. However, little research has been done on the site selection of PHESP, which affects the rapid development of PHESP. Therefore, this paper aims to select the most ideal PHESP site from numerous candidate alternatives using the multi-criteria decision-making (MCDM) technique. Firstly, a comprehensive evaluation criteria system is established for the first time. Then, considering quantitative and qualitative criteria coexist in this system, multiple types of representations, including crisp numerical values (CNVs), triangular intuitionistic fuzzy numbers (TIFNs), and 2-dimension uncertain linguistic variables (2DULVs), are employed to deal with heterogeneous criteria information. To determine the weight of criteria and fully take the preference of the decision makers (DMs) into account, the analytic hierarchy process (AHP) method is applied for criteria weighting. After that, an extended Vlsekriterijumska Optimizacija I Kompromisno Resenje (VIKOR) method is utilized to provide compromise solutions for the PHESP site considering such heterogeneous information. At last, the proposed model is then applied in a case study of Zhejiang province, China to illustrate its practicality and efficiency. The result shows the Changlongshan should be selected as the optimal PHESP.
FVIIa-sTF and Thrombin Inhibitory Activities of Compounds Isolated from Microcystis aeruginosa K-139
Authors: Anas Andrea , Mori Akane , Tone Mineka , Naruse Chiaki , Nakajima Anna , Asukabe Hirohiko , Takaya Yoshiaki , Imanishi Susumu , Nishizawa Tomoyasu , Shirai Makoto , Harada Ken-ichi
Published: August 2017

The rise of bleeding and bleeding complications caused by oral anticoagulant use are serious problems nowadays. Strategies that block the initiation step in blood coagulation involving activated factor VII-tissue factor (fVIIa-TF) have been considered. This study explores toxic Microcystis aeruginosa K-139, from Lake Kasumigaura, Ibaraki, Japan, as a promising cyanobacterium for isolation of fVIIa-sTF inhibitors. M. aeruginosa K-139 underwent reversed-phase solid-phase extraction (ODS-SPE) from 20% MeOH to MeOH elution with 40%-MeOH increments, which afforded aeruginosin K-139 in the 60% MeOH fraction; micropeptin K-139 and microviridin B in the MeOH fraction. Aeruginosin K-139 displayed an fVIIa-sTF inhibitory activity of ~166 µM, within a 95% confidence interval. Micropeptin K-139 inhibited fVIIa-sTF with EC50 10.62 µM, which was more efficient than thrombin inhibition of EC50 26.94 µM. The thrombin/fVIIa-sTF ratio of 2.54 in micropeptin K-139 is higher than those in 4-amidinophenylmethane sulfonyl fluoride (APMSF) and leupeptin, when used as positive controls. This study proves that M. aeruginosa K-139 is a new source of fVIIa-sTF inhibitors. It also opens a new avenue for micropeptin K-139 and related depsipeptides as fVIIa-sTF inhibitors.
Development and Validation of HPLC-DAD and UHPLC-DAD Methods for the Simultaneous Determination of Guanylhydrazone Derivatives Employing a Factorial Design
Authors: Azevedo de Brito Wanessa , Gomes Dantas Monique , Andrade Nogueira Fernando , Ferreira da Silva-Júnior Edeildo , Xavier de Araújo-Júnior João , Aquino Thiago , Adélia Nogueira Ribeiro Êurica , Da Silva Solon Lilian , Soares Aragão Cícero , Barreto Gomes Ana
Published: August 2017

Guanylhydrazones are molecules with great pharmacological potential in various therapeutic areas, including antitumoral activity. Factorial design is an excellent tool in the optimization of a chromatographic method, because it is possible quickly change factors such as temperature, mobile phase composition, mobile phase pH, column length, among others to establish the optimal conditions of analysis. The aim of the present work was to develop and validate a HPLC and UHPLC methods for the simultaneous determination of guanylhydrazones with anticancer activity employing experimental design. Precise, exact, linear and robust HPLC and UHPLC methods were developed and validated for the simultaneous quantification of the guanylhydrazones LQM10, LQM14, and LQM17. The UHPLC method was more economic, with a four times less solvent consumption, and 20 times less injection volume, what allowed better column performance. Comparing the empirical approach employed in the HPLC method development to the DoE approach employed in the UHPLC method development, we can conclude that the factorial design made the method development faster, more practical and rational. This resulted in methods that can be employed in the analysis, evaluation and quality control of these new synthetic guanylhydrazones.
Impact of Dietary Protein and Gender on Food Reinforcement
Authors: Casperson Shanon , Roemmich James
Published: August 2017

Recent evidence suggests that increasing dietary protein may alter reward-driven eating behavior. However, the link between protein and food reinforcement is not known. We sought to determine the extent to which increasing dietary protein alters food reinforcement in healthy adults. In a randomized crossover study, 11 women (age = 25 ± 7 years; Body Mass Index (BMI) = 21 ± 2 kg/m2) and 10 men (age = 22 ± 2 years; BMI = 24 ± 2 kg/m2) consumed normal (15%) and high (30%) protein meals. Food reinforcement was assessed using a computer-based choice task (operant responding with concurrent log2(x) reinforcement schedules) 4 h after lunch. We found that food reinforcement was greater in men than women (p < 0.05) and greater for sweet than savory snack foods (p < 0.02). Gender interacted with dietary protein level (p = 0.03) and snack food type (p < 0.0001). Specifically, we found that increasing dietary protein decreased the reinforcing value of savory foods in women. The reinforcing value for sweet foods did not interact with dietary protein or gender. These results demonstrate the differential effects of dietary protein on the reinforcing value for energy-dense, highly palatable snack foods.
Could Pomegranate Juice Help in the Control of Inflammatory Diseases?
Authors: Danesi Francesca , Ferguson Lynnette
Published: August 2017

Fruits rich in polyphenols, such as pomegranates, have been shown to have health benefits relating to their antioxidant and anti-inflammatory properties. Using data obtained from PubMed and Scopus, this article provides a brief overview of the therapeutic effects of pomegranate on chronic inflammatory diseases (CID) such as inflammatory bowel disease (IBD), rheumatoid arthritis (RA), metabolic and cardiovascular disorders, and other inflammatory-associated conditions, with an emphasis on fruit-derived juices. Most studies regarding the effects of pomegranate juice have focused on its ability to treat prostate cancer, diabetes, and atherosclerosis. However, pomegranate juice has shown therapeutic potential for many other illnesses. For instance, a small number of human clinical trials have highlighted the positive effects of pomegranate juice and extract consumption on cardiovascular health. The beneficial effects of pomegranate components have also been observed in animal models for respiratory diseases, RA, neurodegenerative disease, and hyperlipidaemia. Furthermore, there exists strong evidence from rodent models suggesting that pomegranate juice can be used to effectively treat IBD, and as an anti-inflammatory agent to treat CID. The effects of pomegranate intake should be further investigated by conducting larger and more well-defined human trials.
Flavonoid-Rich Extract of Paulownia fortunei Flowers Attenuates Diet-Induced Hyperlipidemia, Hepatic Steatosis and Insulin Resistance in Obesity Mice by AMPK Pathway
Authors: Liu Chanmin , Ma Jieqiong , Sun Jianmei , Cheng Chao , Feng Zhaojun , Jiang Hong , Yang Wei
Published: August 2017

The flavonoid-rich extract from Paulownia fortunei flowers (EPF) has been reported to prevent obesity and other lipid metabolism disease. However, the mechanism of its protective effects is not yet clear. The objective of this study was to investigate molecular factors involved in the hypoglycemic and hypolipidemic effects of EPF in obese mice fed a high-fat diet (HFD). Male h ICR (Institute of Cancer Research) mice were fed a HFD containing or not containing the EPF (50 or 100 mg/kg) for eight weeks. EPF reduced body weight gain, lipid accumulation in livers and levels of lipid, glucose and insulin in plasma as well as reduced insulin resistance as compared with the HFD group. EPF significantly decreased serum aminotransferase activity of the HFD group. We observed that EPF administration significantly increased the level of AMP-activated kinase (AMPK) phosphorylation and prevented fat deposits in livers and HepG2 cells, but these effects were blocked by compound C (an AMPK inhibitor). The protective effects of EPF were probably associated with the decrease in HMGCR, SREBP-1c and FAS expressions and the increase in CPT1 and phosphor-IRS-1 expressions. Our results suggest that EPF might be a potential natural candidate for the treatment and/or prevention of overweight and hepatic and metabolic-related alterations induced by HFD.