bluuebunny/crossref_metadata_2025 huggingface dataset:
THE ROSAS COHORT: A PROSPECTIVE, LONGITUDINAL STUDY OF BIOMARKERS FOR ALZHEIMER’S DISEASE. STRATEGY, METHODS AND INITIAL RESULTS
Authors: de Mauléon A. , Soto M. , Kiyasova V. , Delrieu J. , Guignot I. , Galtier S. , Lilamand M. , Cantet C. , Lala F. , Sastre N. , Andrieu S. , Pueyo M. , Ousset P.J. , Vellas B.
Published: November 2021

Objective: The aims of the Research Of biomarkers in Alzheimer’s diseaSe (ROSAS) study were to determine the biofluid and imaging biomarkers permitting an early diagnosis of Alzheimer’s disease and better characterisation of cognitive and behavioural course of the pathology. This paper outlines the overall strategy, methodology of the study, baseline characteristics of the population and first longitudinal results from the ROSAS cohort. Methods: Longitudinal prospective monocentric observational study performed at the Alzheimer’s disease Research centre in Toulouse. A total of 387 patients were studied and analyzed in 3 groups: 184 patients with dementia of Alzheimer’s type, 96 patients with memory disorders without dementia (Mild Cognitive Impairment) and 107 patients without abnormal memory tests (control group), and were followed up during 4 years. Patient’s sociodemographic characteristics, risk factors, medical conditions, previous and current medications, neuropsychological assessment and overall cognitive status were recorded. Blood and urine samples were collected at every year, Magnetic Resonance Imaging were performed at inclusion, after one year of follow-up and at the end of the study. Results: At baseline, three different groups of the cohort differed interestingly in age, level of education, and in percentage of ApoEε4 carriers whereas the history of cardiovascular and endocrine pathologies were similar among the groups. During the follow-up period (3-4 years) 42 mild cognitive impairment patients (43.8%) progressed to dementia, 7 controls progressed into mild cognitive impairment and 1 patient in the control group converted from mild cognitive impairment group to dementia of Alzheimer’s type group. During the first year of follow up, the incidence of progression from mild cognitive impairment to dementia of Alzheimer’s type was 12.7 per 100, during the second year 33.9 per 100 and 46.7 per 100 for the third year. Conclusion: This paper presents the baseline characteristics of the unique French prospective monocenter study in which the natural course of dementia of Alzheimer’s type was evaluated. Future analysis of blood and urine samples collection from the ROSAS study will permit to identify possible biofluid biomarkers predicting the early stages of the dementia of Alzheimer’s type and risk of progression from Mild Cognitive Impairment to Alzheimer’s disease.
The Analysis on the Annual Change of Digital Aerial Camera's IMUs Boresight Misalignment
Authors: Kayı Abdullah , Bayram Bülent , Şeker Dursun Zafer
Published: November 2021

The system calibration determines the position and orientation between the sensor and the navigation systems, such as boresight misalignment. Although there is much research about boresight calibration, there are not sufficient studies on the frequency of the calibration performance.
The short-term stability of boresight misalignment was investigated in previous studies, but long-term stability research could not be done. It is important to emphasize that long-term stability is still open to questions. In this study, an Ultracam Eagle digital aerial camera's data from
2012 to 2016 were analyzed and the question of how often calibration should be performed was investigated. Boresight misalignment does not remain constant on a yearly basis and should be calibrated every year before the flight season. It was observed that the boresight misalignment changed
dramatically when the inertial measurement unit or camera was removed from the aircraft and sent to the manufacturer for factory calibration.
Yuval N. Harari: la libertad difuminada y desmitificada
Authors: Beorlegui Carlos
Published: November 2021

La lectura de los textos del mediático escritor Yuval Noha Harari producen una serie de sentimientos muy enfrentados: van de la admiración a la perplejidad. Admiración y perplejidad por su gran capacidad de síntesis, neologismos muy logrados, aportación de ideas sugerentes y acertadas, tanto respecto al pasado como a nuestro futuro cercano, etc. Pero Harari tiene también sus limitaciones, debilidades y contradicciones. Eso ocurre de forma especial cuando el intelectual israelí reflexiona sobre la libertad humana, uno de sus temas recurrentes, que está presente de forma especial en sus trabajos últimos, así como en sus diversas entrevistas a los medios de comunicación.
Scholars and Literati at the Saint Petersburg Academy of Sciences (1724–1800)
Authors: De la Croix David , Doraghi Mehrdaad
Published: November 2021

This note is a summary description of the set of scholars and literati who participated in the activities of the Saint Petersburg Academy of Sciences, from its inception in 1724 to the eve of the Industrial Revolution (1800).
Relaciones ciencia-tecnología-sociedad en la educación científica colombiana: una revisión del estado de la cuestión (2017-2021)
Authors: Alvarez-Tobón Yisneth-Nathaniela , Arroyave-Giraldo Dora-Inés , García-Carmona Antonio
Published: November 2021

En este artículo se presentan los resultados de una investigación documental cuyo objetivo fue analizar las tendencias sobre el abordaje de las relaciones ciencia-tecnología-sociedad (CTS) en la educación científica en Colombia, entre los años 2017 y 2021. Se empleó, para ello, una metodología cualitativa basada en el análisis textual discursivo de los documentos seleccionados, con ayuda del software Nvivo11. Las categorías de análisis fueron: tipo de estudio, metodología, población, contexto didáctico CTS, e incorporación de las relaciones CTS en la educación científica. Entre otros resultados, se observó un empleo recurrente de la historia y la epistemología de la ciencia, así como el uso de controversias científicas, para abordar las relaciones CTS en la educación científica del contexto colombiano.
Techniques to Push and Withdraw Knowledge on Time to Achieve Performance Beyond Expected: An Analytical Study in the Office of the Ministry of Higher Education and Scientific Research
Authors: Al-Rubaye Dr. Sumaya Abbas Majeed
Published: November 2021

The study is based on the idea that for a good determination of the techniques adopted in pushing or withdrawing information and knowledge according to the requirements of the type of decisions and according to the appropriate time will lead to achieving a performance that exceeds the ministry's expectations and outside the familiar and the scheme and on that the researcher used the philosophical analysis and preparation of a questionnaire using the Likert pentagon scale and the adoption of descriptive and statistical analysis of the side results Practical, where I found a correlation and influence between the variables of the study, but it is relatively medium in most of its variables to show the ministry's need to support and enhance the capabilities necessary for workers to obtain knowledge at the specified time for the urgent need for them to accomplish the tasks entrusted to them.
Internet of Things (IoTs) Effects and Building Effective Management Information System (MIS) in Vietnam Enterprises and Human-Computer Interaction Issues in Industry 4.0
Authors: Nam Vu Quynh , Huy Dinh Tran Ngoc , Hang Nguyen Thi , Le Trung-Hieu , Thanh Nguyen Thi Phuong
Published: November 2021

In recent years there is a rising need in Vietnam enterprises to build an effective management information system in order to deliver better information for management levels to make a proper decision. This paper mainly use qualitative analysis with statistics, synthesis and inductive methods, combine with dialectical materialism methods. Research results indicate that in industry 4.0 under Internet of Things (IoTs) effects, Vietnam enterprises such as hospitals and renewable energy companies or manufacturing firms can use advanced cloud technology to store and process big data of clients to serve for a better MIS system or risk MIS system. IoTs together with Big Data and cloud technology also prove better solutions to accounting and human resources of businesses. Last but not least, this study also propose some solutions to deal with challenges in constructing risk information system in Vietnam enterprises during covid 19 impacts. For instance, we need to invest more on technology infrastructure and take advantage of IoTs effects to build effective MIS for companies to make sound decisions.
A Hybrid Capsule Network with Attention and BiLSTM for Opinion Mining in Text
Authors: Guha Tapas , Mohan Dr.K.G.
Published: November 2021

Examining the product review or review on web service facilitate to increase the product quality or web service. By means, comments from online shopping sites such as Amazon, Flipkart, EBay etc will not only assist the users to purchase the product however besides be able to guide the producer/supplier to identify the advantages and disadvantages of the goods. Mining online shopping websites with their information will becomes a major important task. Web Mining plays a major important role to mine the details of online websites efficiently. Web mining is the process of data mining that learns without human intervention and mine information obtained from the documents in web and also services. Sentiment categorization and web mining has become a truly significant task recently, with profound business and research impact. Machine learning algorithms and soon after deep learning methods have been the market leaders in sentiment analysis. The advent of capsule networks has been a landmark event in deep learning. It has been truly proficient in image processing. In case of text classification, standalone capsule networks are not optimally suitable. Here, a hybrid BiLSTM-Capsule framework is introduced for sentiment analysis of web texts of reviews from various datasets. In the model beginning, there is a bidirectional LSTM layer after which is an attention layer and a final capsule layer. This review analysis will helps to improve the products from amazon, increase the movie quality. The analysis of outcome depending on MR, IMDB, SST and Amazon datasets indicated the introduced framework performs better than some benchmark deep learning models. Significantly, the BiLSTM-Capsule can put its words in sentimental trend showing the capsules’ attributes without utilizing the linguistic knowledge.
Tourist Shopping: Critical Determinants of Willingness to Pay
Authors: Boonchai Paranee , Ghuangpeng Siriwan , Lakornsri Tanida
Published: November 2021

Recently, the concept of consumer willingness to pay has fascinated attention from marketers and Destination Marketing organizations (DMO) to increase national income. Despite the growth of destination competitiveness, demands remain for a more sophisticated understanding of consumer purchasing behavior construction. This paper investigates determinant factors of tourist shopping and its resulting impact on willingness to pay. Finding reveals tourists had to respond of willingness to pay (WTP) in the drivers of stimulator and organism in terms of leisure value and monetary value derived from the retail atmosphere, town environment, and product orientation. This study contributes to supporting literature by shedding light on the drivers of WTP in tourist shopping contexts.
Working Capital Optimization: A Supply Chain Perspective
Authors: Al-Duleimy Haidar Hamza Jody , Jebur Shatha Abdul Hussein
Published: November 2021

The reason for this study is to examine the effect of working capital optimization on the efficiency of Iraqi companies across various industries. The study uses least square model and panel data used for four industries. The analysis gives empirical confirmation that cash conversion cycle used as a proxy of working capital and impact significantly and negatively impact on profitability of the firm and also firm level control factor age and industry influence on the firm performance. Such results indicate that administration can improve organizational profitability by reducing its working capital. The findings of this study can be examined in various socio-economic and industrial contexts. This research is limited to the Iraqi context. This research applies the existing body of information to investigate a panel data set in the context of a developing economy by using the regression equation. This innovative research explores empirically the effect of working capital management on the performance.
Customized Learning Model Using Learner Activity Analysis
Authors: Revathi A. , Kaladevi R. , Gayathri A. , Manju A.
Published: November 2021

Reshaping education with knowledge and skills is the major objective of many of the developing organization to build competitive knowledge economy. Electronic learning, also popularly known as e-learning is one of the most effective applications of Information and Communication Technology (ICT), which refurbishes the dimension in higher education. COVID-19 pandemic situation justifies the need and real utilization of E-learning. Existing E-learning system provides static content to all learners irrespective of their learning needs. In this paper we propose to create Dynamic Role based access control model based on information from learners needs, audit logs and observations to support adaptive E-learning systems.
Cloud and Mobile Systems as a Means of Forming Professional Competencies in Economics and Engineering Students
Authors: Tyger Lyubov Mikhailovna , Afonin Mikhail Vctorovich , Sekerin Vladimir Dmitrievich , Artemyeva Svetlana Ivanovna , Andreev Anatoly Nikolaevish , Avdeeva Tatyana Ivanovna
Published: November 2021

The study is relevant since there is a contradiction between growing requirements for the informational and communicative competence of different students, including the use of cloud-based computer modeling systems, and the insufficient use of cloud technologies in teaching bachelors of economics and technology. The study aims at determining cloud-based systems that are advisable to use as a means of forming the professional competencies of future specialists in economics and technology and developing guidelines for their use. Based on the analysis of various programs, the authors have proved that the most appropriate is the use of specific software in the professional training of future specialists. Scattered software and cloud services need integration based on unified access that a Google account can provide. They also developed a method of using cloud technologies as a means of forming the informational and communicative competence of bachelors of economics and technology. The use of cloud-based information and communication technologies ensures an increase in the level of professional competence of future specialists.
IOT Impacts and Digital Transformation at Listed Vietnam Banks
Authors: Hang Dr. Nguyen Thi , Huy Dinh Tran Ngoc , Hien Dinh Thi , Nam Vu Quynh
Published: November 2021

The Industrial Revolution 4.0 based on digital technologies has led to an unprecedented change in the socio-economic model. Therefore, countries in general and Vietnam are all aiming to develop the digital economy. The concept of digital transformation of the economy or development of the digital economy in Vietnam focuses on the following basic contents: 1) Developing digital businesses; 2) Digital transformation for traditional businesses (towards digitally integrated products; transforming business models on digital platforms; changing production processes based on digital data, automation, virtualization, etc.); 3) Development of digital finance; 4) E-commerce development. Therefore, digital transformation becomes an inevitable and objective trend, supporting banks to overcome challenges, create competitive advantages, and actively adapt to the context of digital transformation. In the context of the development of the digital economy in Vietnam is taking place strongly across industries and fields, requiring banks in Vietnam to have a transformation to a new business model. In this business model, it is necessary to integrate technology in operations and digitize business processes in the direction of automation and intelligence. Thereby, banks can perform activities of providing products and services on digital platforms, effectively exploiting data, thereby increasing experiences in business resolution and customer engagement. Besides, Internet of things has connect everything through internet, therefore risk management information system of Vietnam banks is also affected by IoTs and reliable internet data can help to enhance better RMIS in commercial banks. Generally, we want to emphasize effects of IoTs and digital transformation in banks operation and new business models.
Impact of Globalization and Informatization on the Development of National Economies
Authors: Chernysheva Anna Mikhailovna , Zobov Alexandr Mikhailovich , Bulatenko Maria Andreevna
Published: November 2021

The purpose of this paper is to analyze the existing interconnectedness between national economies in the context of globalization of the world economy. The principal methods of research were the search, systematization, assessment and analysis of macroeconomic indicators and subsequent inferences regarding the interdependence of national economies in the context of globalization of the world economy. It is shown that the modern stage of international economic relations has brought about the close interconnectedness between national economies amid the rapid globalization, which may though evolve in an asymmetric way under the influence of regional and internal factors.
Intangible Assets of a Trade Organization in the Context of Digital Transformation
Authors: Cheglov Vyacheslav Petrovich
Published: November 2021

The paper explores the aspects of formation, valuation and developmental resource of intangible assets in trade amid the growing role of online sales channels. The existing criteria of categorising the resources of trade companies as intangible assets are analysed with a focus on their suitability for the established practices. The structure of intangible assets is analysed for online and offline trade. The relevant types of intangible assets are identified and valuation problems are described.
Influence of Content on Consumer and Employee Brand Engagement in Facebook (Russian FMCG Retail Sector)
Authors: Shilovsky Sergey Vitalievich
Published: November 2021

Social networks provide companies with great opportunities to build relationships with consumers. Currently, almost every company has their own brand page in social networks and is trying to enhance consumer engagement. Company posts are shown to brand community members. Most researchers believe that the brand community consists only of consumers. However, based on the service-dominant logic of marketing, the brand enters into relations not only with consumers, but also with other stakeholders, including employees of the company, who can be members of the brand community in the social networks. In this research, we focus on FMCG retailers brand community. The algorithm of Facebook social network ensures the dependence of consumer engagement on employee brand engagement. Retail marketers need to use content to influence not only consumer engagement, but also employee brand engagement, expressed in likes, comments and shares. The author analyzes 460 Facebook posts made by 5 Russian FMCG retailers’ brands during a 6-month period. A theory-based typology of content characteristics was made and it covers of what brands say and how they say it. This research sheds light on how content influence consumer and employee brand engagement in social networks.
Forecasting Model for the Value of Areca Nut’s Export of Thailand
Authors: Phakdi Phanita
Published: November 2021

Having accurate information about the agricultural situation is very important. The predicting trends of agricultural product will allow to make right decision in economy nowadays. The aims of the paper are to demonstrate the trend in areca nut export in Thailand and import in India to specific period and to plan our strategy and policies accordingly to promote areca nut production and export. With this meaning, a study on areca nut export in Thailand and import and production in India from 2013 to 2020 was conducted. The result found that Exponential Growth Model is the most effective for forecasting in the export and import volume of areca nut. The data also was illustrated the trends in 5 years from 2021- 2025. The result revealed that the forecasting trend of export volume of areca nut in Thailand for 2021 – 2025 is linearly decreasing from 3.47610MTs in 2020 to 0.450858MTs in 2025. While, the forecasting trend of import volume of areca nut in India for 2021 – 2025 is linear increasing gradually, from35.5783 MTs in 2020 to 37.2886 MTs in 2025. Areca nut should be considered as an economics crop significantly of Thailand in future for export of Thailand because there are needs in the international market and price still be reasonable. Driving and implementing sustainable agriculture should focus on efficiency and effectiveness truly.
Opportunities of Using IT Compliance Tools as an Organization's Management Function
Authors: Kuznetsov Nikolay Vladimirovich , Reshetnikov Stanislav Borisovich , Silvestrov Sergey Nikolaevich , Pobyvaev Sergey Alekseevich
Published: November 2021

The present article deals with the study of the application and regulatory consolidation of the IT compliance function in both commercial and state-financed organizations. In addition to studying the application of this function, the article focuses on the issues of building a compliance system in the organization. In the main part of the work, compliance is considered as a system of measures taken by an organization for its effective operation. A detailed analysis of the advantages and disadvantages of the concerned system is presented, as well as the authors’ assessment of the risks and prospects associated with the implementation and application of the compliance methodology within the enterprise.
Patient Acceptance of Educational Contents in Asma Droid for Learning Asthma Self-Management
Authors: Ghozali MT , Al-Islami Muhammad Bimbo , Purbaningrat Irvando
Published: November 2021

Education on proper asthma self-management is important in the management of asthma. It is a strategy to improve the quality of life and clinical outcomes of asthmatics. In this modern era, almost all digital contents, including health promotion and patient education, can be simply carried out through a smartphone app. Unfortunately, not all patients accept this approach. A well-validated method, known as the Technology Acceptance Model, was adopted to ensure the acceptance of the contents by users, in this case, patients. This study aimed to determine the perceived usefulness and perceived ease of use in the patient acceptance of educational contents of an asthma self-management app, known as AsmaDroid. The design of this study was an explanatory model with a quantitative approach. The respondents were asthmatics with the following criteria: aged 19–22 years old, having a history of asthma, and having installed and used the AsmaDroid app for a month. The purposive sampling approach was adopted with 100 study respondents, and the instruments of the study were AsmaDroid and a TAM questionnaire. Additionally, a descriptive statistic was also adopted with the use of multiple linear regression to prove the study hypothesis. The results of this study showed that both perceived usefulness and perceived ease of use had a positive and significant effect on the user or patient acceptance, with a significant value of 0.00 and 0.02, respectively. This study concluded that asthma educational contents in AsmaDroid provided benefits and convenience for users. Therefore, the educational contents were accepted as an alternative medium to learn asthma self-management.
The Effect of Media Technology on Electronic Shopping
Authors: Abd Ali Hussein Najm , - -
Published: November 2021

Social networking helps create greater online presence, leads and traffic for businesses. Strategic social media preparation is an integral part of an E-commerce sector. Social media continues to achieve global prominence because of commercial success. There is a great percentage of promotional campaigns taking place via social media platforms. Getting social media presence can make ecommerce even more useful. It makes it incredibly convenient to draw consumers via social media. Social media has motivated many people to buy different things, you know. Lots of firms have been able to market their goods and business through Facebook and other social networking platforms. Generally, only bigger corporations can use social media. To build profitable company on social media, you need to set specific goals. Companies now use social media with the intention of expanding their market. Social networking has the potential to boost revenue and it is an efficient cost-efficient way to communicate with customers. If you connect with your customers on Facebook and Twitter, you will be able to figure out what your customers want. Social networking sites cater for conversational features by 'liking' and 'discussing' features. Sharing knowledge online is relevant because it affects the decisions taken by customers when purchasing goods and services. A perfect way to promote your company is to add Sharing buttons for social media sites on your website. In this way, it's likely that you'll raise the number of users your site gets. Several individuals base their buying choices on things seen in the internet. Social media play a major part in one's networking and selling practices. Consumers around the world will be spending billions of their hard earned dollars yearly on social media sites.
Kistérségnek is jár a nagy brand? A vajdasági Magyarkanizsa márkaépítése mint jó gyakorlat
Authors: Bödő Marianna , Papp-Váry Árpád Ferenc
Published: November 2021

Az elmúlt években a kistérségek egy része egyre komolyabban foglalkozik a márkaépítéssel. A marketing segítségével szeretnék megmutatni, hogy milyen értéket rejtenek, és ez által mind a turisták számára vonzóbbá tenni az adott területet, mind az ott élők büszkeségét növelni. Esetükben a turisztikai kínálat szorosan kapcsolódik a természeti kincsekhez, a hagyományokhoz és a történelmi örökséghez. A falusi-, öko- vagy épp a kalandturizmus, mint egyre népszerűbb szabadidő töltési formák új lehetőségeket tárnak fel számukra, ami hozzájárul a kistérségek fejlődéséhez és egyben megélhetési forrást biztosit az ott élők számára. A turistákért azonban nagy a verseny és a pandémia után várhatóan még nagyobb lesz. Ebben a kiélezett versenyhelyzetben felmerül a kérdés, hogy mi lehet az a húzóerő, amely egy adott térséget kiemel a többi közül, amiben többet tudhat, többet nyújthat, mint a versenytársak? A tanulmányban erre mutatunk be egy jó példát, gyakorlatot, mely más kistérségek számára is inspiráló lehet. A vajdasági Magyarkanizsa a 2019-2020 időszakban egy idegenforgalmi marketingstratégiával állt elő, amellyel egyszerre célzott a szerbiai és a magyarországi utazókra is. A projektnek köszönhetően Magyarkanizsa kiemelkedett a vajdasági kistérségek közül, és 2020 júliusában és augusztusában, amikor enyhültek a szerbiai járványügyi korlátozások, nagy számú látogató fordult meg a térségben. A kistérség jól használta ki, hogy a koronavírus hatása miatt felértékelődtek a közeli desztinációk és a sikeres marketing tevékenységnek köszönhetően Budapesttől Belgrádig sokan választották Magyarkanizsát üdülőhelyként. A térség iránti megnövekedett érdeklődést támasztják alá a közösségi média statisztikák is, melyeket a cikkben részletesen bemutatunk.
A produktív tanulás alternatív modellje
Authors: Fodor Bálint
Published: November 2021

Az elmúlt évtizedek során a köznevelést érő kritikák egyik visszatérő fő eleme az iskolát elhagyó diákok munka világába történő átlépésének nehézsége, az iskolát követő kihívásokra történő inadekvát felkészítés volt. Habár a 20. század legtöbb iskolarendszere többé-kevésbé igyekezett tükrözni az adott ország társadalmi berendezkedését, modellezni az iskolából kilépő fiataltól elvárt társadalmi működést, mégis folyamatosan fennálló probléma volt, hogy az akadémiai tudás mellett kevesebb hangsúlyt kap a személyes boldogulásra való felkészítés. A hazai középiskolai ballagásokon annyiszor elhangzó mondat: „Most végre kiléptek a nagybetűs Életbe!” önmagában üres állítás, ha nem próbálunk jelentést társítani ehhez az úgynevezett „Élethez”. Mi az Élet, mire számíthat a fiatal felnőtt – nem csupán munkavállalás, családtervezés terén, hanem saját sorsának tudatos alakítójaként?
A produktív tanulás alternatív modelljére tekinthetünk úgy is, mint a produktív élet leképződésére. Ahogy az iskola világában, úgy az annak (ideális esetben) modellt adó társadalomban is alkalmazható modellre van szükség, mely egyaránt leírja az eredményes iskolai előrehaladás egyik módját, és a sikeres és tartalmas – azaz produktív egyéni, személyes fejlődést. A produktív tanulás alternatív modellje tehát nem csupán az iskolai-, de a személyes és társadalmi dimenziókban is egyaránt értelmezhető és alkalmazható. Egyaránt vizsgálhatunk vele iskolai tanórát, óvodai foglalkozást, egyetemi kurzust, céges továbbképzést – vagy akár saját személyiségfejlődésünket.
INVESTIGATION OF SEVERAL FACTORS ON ENZYMATIC HYDROLYSIS OF SUGAR BEET PULP AND CORN COB: STATISTICAL ANALYSES OF THE EXPERIMENTAL RESULTS
Authors: LEYLUHAN YURTSEVEN Berna , CIKRIKCI ERUNSAL Sevıl , ÖZTOP Mecit Halil
Published: November 2021

In this work, sugar beet pulp (SBP) as a lignin poor biomass and corn cob (CC) as a lignin rich biomass were subjected to enzymatic hydrolysis to see the effects of various variables on reducing sugar yield. In SBP hydrolysis, response surface methodology (RSM) and ANOVA were used to fit sugar yield and to determine significance of the parameters (substrate, pectinase, cellulase and hydrolysis time). The proposed quadratic model gave an adequate approximation indicating the significance of all main effects and some of the interaction effects (p < 0.05). The maximum yields within the design space were found approximately as 87 g/L after 18 h of hydrolysis, using 300 µl Cellic Ctec3 and 300 µl Pectinex Ultra SP-L at %20 substrate loading. In CC hydrolysis, the use of nonionic surfactants (Tween 20 and Tween 80) under unpretreated conditions did not necessarily increase the yield of reducing sugar from untreated CC.
Undergraduate Students’ Self-Efficacy Strategies in Writing Academic Papers
Authors: Sumarsono Anne Yustica Pramesti , Mbato Concilianus Laos
Published: November 2021

This study explored the writing self-efficacy of English education undergraduates at Sanata Dharma University, Yogyakarta. Nowadays, many students still have not used self-efficacy in their studies. Consequently, they may encounter difficulties when working on tasks. As a result, the scores obtained are not the highest. Which may make them lack the motivation to learn. The purpose of this research was to determine the application of self-efficacy in writing works for the undergraduate course of English Education at Sanata Dharma University. The research question was: How can undergraduate students of the English Education Study Program manage self-efficacy and writing anxiety to complete the academic writing class? This research adopted qualitative methods making use of the Likert scale and interviews. The questionnaire was distributed to Sanata Dharma University’s undergraduates who had received English courses in reading literary works. The results show that undergraduates have a high sense of self-efficacy, can complete academic writing on time, and we are motivated by their internal and surrounding environments.
Emergence and Development of Bullet Comments in China
Authors: Wang Aiqing
Published: November 2021

Danmu denotes user-generated dynamic and contextualised comments scrolling across the screen. Owing to its resemblance to a bullet curtain, such a text-over-screen technology is referred to as ‘bullet comment/message’ or ‘barrage subtitling’. Since being adopted from Japan, danmu has expeditiously developed from a niche subcultural entity into a prominent property of Chinese online video culture. Danmu obtains popularity among young audiences, in that it establishes social media co-viewing, creates a sense of belonging, allows self-expression and facilitates social connectedness. Moreover, danmu enables creators to demonstrate a sense of existence, especially via informative, alerting and spoiler comments. The popularity of danmu in China is ascribed to diversified and concise literacy practice. More significantly, it is attributed to linguistic and cultural prerequisites: the Chinese written language is featured by a high information density and robust parafoveal preview effects; the Chinese culture is marked by a high level of polychronicity and collectivism, as well as conspicuous social and peer pressure.
Investigating Translation Technique: A Result of the Students’ Work on Subtitling for the Deaf and Hard of Hearing
Authors: Aminudin Muhammad Fauzan , Hidayati Anni Nurul
Published: November 2021

The modern era, especially in the global pandemic Covid – 19, the need of information, knowledge and entertainment becomes a crucial part since the activities must go online. The government rule stated that the information shall be accessible for anyone, the deaf and hearing impaired, for instance. This descriptive qualitative study aims to investigate the translation technique done by the students in working for subtitling for the deaf and hard of hearing (SDH) in Audiovisual translation class. The finding of 208 data revealed that there are 12 of 18 techniques applied proposed by Molina and Albir. The most dominant technique is literal translation, besides it showed that the students as a subtitlers may apply one or more techniques during doing the subtitling. As a pedagogical implication to this study, the results can be considerations in designing the curriculum for Audio visual translation subject with complete theories and practices, especially in terms of building the emotion and characterization
Place Names in Ekegusii Language: A Cognitive Linguistics Approach
Authors: Onchoke Aunga Solomon
Published: November 2021

This paper analyses place names in the Ekegusii language from the cognitive linguistics point of view. The study is grounded on three objectives: to identify and explain the Ekegusii names of places, to describe the social cultural values, and to account for the cognitive processes involved in their mapping, analysis and elucidation. The data comprises of a list of Ekegusii place names collected from two counties, Kisii and Nyamira, by interviewing people through snowballing, and later holding a panel discussion with selected elders regarding the mapping processes and meanings associated with them. The Cognitive Metaphor Theory was used to map them to the different types of conceptual domains. Findings from this study show that place names in Ekegusii are conceptualized as seasons, topography, people, animals, plants and objects (as source domains which are social-culturally determined), and portray their cultural identity and tradition. The study concludes by suggesting further research in onomastics, especially on metaphor and metonymy in other languages of the world.
Effect of Mangkokan (Polyscias scutellaria) Leaf Extract on Blood Sugar Levels in Alloxan-Induced Male White Rats
Authors:   Department of Public Health,Faculty of Medicine Universitas Prima Indonesia, Medan, Indonesia, Nasution Sri Lestari Ramadhani , Awanis  , Elsafarindo Stiven
Published: November 2021

Type 2 diabetes is a metabolic disorder caused by insulin resistance and is associated with oxidative stress. In Indonesia, the mean prevalence of diabetes ranges from 1.4% to 1.6%; however, some areas have a much higher diabetes prevalence such as Pekajangan (2.3%) and in Manado (6%). The 2013 Indonesian Basic Health Research (IBHR) stated that the number of people with DM in Indonesia has reached an alarming rate. This study aimed to determine the antidiabetic effect of Polyscias scutellaria on alloxan-induced male Wistar. This was an experimental study conducted in July 2020 in the Faculty of Medicine, Prima Indonesia University. This study used 25 rats that were grouped into 5 treatment groups: control group (Na-CMC), standard (Metformin), and 3 extract groups with different doses (125 mg/kg BW, 250 mg/kg BW, and 500 mg/kg BW). Mangkokan leaf extract was obtained through the maceration method. All ratswere induced intraperitoneally using alloxan monohydrate 10% at a dose of 175 mg/kg BW. The parameters used in this study were fasting blood glucose level before induction, after induction, and after treatment and body weight before treatment. It was observed that there was a significant change in blood glucose level between the extract groups. The blood sugar level in the 125 mg/kg BW group was 495.00 mg/dl while in the 250 mg/kg BW and 500 mg/kg BW, the blood glucose levels were 317.00 mg/dl and 126.00 mg/dl, respectively, with the 500 mg/Kg BW dose as the most effective dose (P-value = 0.001). Thus, mangkokan leaves have the potential to reduce blood glucose level but are not as good as the standard group.
Association between Refractive Error Types and Asthenopia in Primary School Students
Authors:   Faculty of Medicine and Health Sciences Atma Jaya Catholic University Indonesia, Kuswanto Vanessa , Kurniawan Felicia , Amita Angela Shinta Dewi
Published: November 2021

Refractive error is a condition in which the cornea and lens fail to focus the light, resulting in reduced visual efficiency. Twelve million children are experiencing refractive errors worldwide and uncorrected refractive errors in children have been reported to cause asthenopia. This study aimed to determine the association between the types of refractive errors and asthenopia in children. This cross-sectional study was conducted on 111 students aged 10-13 years old in a public elementary school in Indonesia, SDN Penjaringan 10, in 2019. A questionnaire was used to assess asthenopia and the Snellen Chart, trial frames, and trial lenses were used for refractive errors examination. It was demonstrated that 87.4% of respondents experienced asthenopia, and 53.2% of respondents suffered from uncorrected refractive errors, mostly due to myopia. Fisher’s exact test results showed an association between refractive errors and asthenopia (p=0.019) with all myopic students experienced asthenopia. However, there was no significant association between astigmatism and asthenopia (p=0.754). In conclusion, not all types of refractive errors are associated with asthenopia.
Characteristics of Enterovesical Fistula Patients Visiting the Urology Department of Dr. Hasan Sadikin General Hospital Bandung, Indonesia, from 2015 to 2019
Authors:   Department of Urology, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung, Indonesia, Saputra Daniel , Tjahjodjati
Published: November 2021

Enterovesical fistula (EVF) represents an abnormal channel between the intestine and the bladder. The EVF is a complication of inflammatory or neoplastic diseases and injuries. Diagnosis of EVF can be challenging and often delayed up to several months after the onset of the symptoms. This study aimed to determine the characteristics of patients with enterovesical fistula visiting Dr. Hasan Sadikin General Hospital Bandung, Indonesia. This retrospective descriptive study used the medical records of EVF patients treated in the urology department of Dr. Hasan Sadikin General Hospital from 2015 to 2019 as the secondary data to be analyzed. A total of 58 patients with EVF were enrolled in this study. By gender, that more than half of the patients were male patients (n=30, 51.7%) and 45% of patients were between 41 and 50 years old. The most common symptoms of EVF were pneumaturia and fecaluria which were seen in 30 (51.7%) and 20 (34.5%) patients, respectively. Twenty-nine (50%) patients experienced malnutrition and 18 (31.1%) patients had diabetes mellitus as a comorbid. The most common type of fistula was rectovesical fistula (n=45, 77.6%) and 26 (66.6%) patients suffered from rectosigmoid cancer and malignancy (68.95) had become the most predominant etiology. Escherichia coli was found in 42 (72.4%) urine cultures collected from the patients and cystoscopy with fistula biopsy was found in 43.1% of cases, followed by fistula repair (29.3%) and urethral catheter drainage (15.5%). Hence, malignancy and rectosigmoid cancer become the most common etiology of EVF while cystoscopy with fistula biopsy is the most frequently performed procedure.
Smart-Specialization of the Agro-Industrial Complex in the Context of Digital Transformation of Regional Economic Systems
Authors: Kulik Anna M , Lavrinenko Elena A , Lyshchikova Julia V , Stryabkova Elena A
Published: November 2021

This article presents a domestic and foreign experience of "smart specialization" in agriculture in the digital economy. The method of calculating the indicators of digital maturity of the agro-industrial complex is considered. The forecast of indicators value of the agro-industrial digital maturity is presented until 2030. The article proposes a mechanism for adapting the smart specialization in agriculture. We consider it appropriate to introduce an online digital platform in agriculture, which allows creating conditions for interaction between sellers and buyers of regional agricultural machinery and related products. Based on the presented mechanism of adaptation of "smart specialization "in the field of agro-industrial complex, it should be noted that" smart specialization" is aimed at using the links that arise between the regions of economic activity. The priority areas of activity of the agro-industrial complex are presented.JEL Classification: L52, Q16, R11How to Cite:Kulik, A. M., Lavrinenko, E. A., Lyshchikova, J. V., & Strybkova, E. A. (2021). Smart-Specialization of the Agro-Industrial Complex of Digital Transformation of Regional Economic System. Etikonomi, 20(2), xx– xx. https://doi.org/10.15408/etk.v20i2.22015.
Improving Opioid Stewardship in Pediatric Emergency Medicine
Authors: Lavingia Richa , Mondragon Ealing , McFarlane-Johansson Nina , Shenoi Rohit P.
Published: November 2021

OBJECTIVES

Poor opioid stewardship contributes to opioid misuse and adverse health outcomes. We sought to decrease opioid prescriptions in children 0 to 18 years treated for pain after fractures and cutaneous abscess drainage from 13.5% to 8%. Our secondary aims were to reduce opioid prescriptions written for >3 days from 41% to 10%, eliminate codeine prescriptions, increase safe opioid storage and disposal discharge instructions from 0% to 70%, and enroll all emergency department (ED) physicians in the state prescription drug monitoring program.

METHODS

We implemented an intervention bundle on the basis of 4 key drivers at a pediatric ED: ED-wide education, changes in the electronic medical record, discharge resources, and process standardization. Two plan-do-study-act cycles were performed. Interventions included provider feedback on prescribing, safe opioid storage and disposal instructions, and streamlined electronic medical record functions. Run charts were used to analyze the effect of interventions on outcomes. Our balance measure was return ED or clinic visits for inadequate analgesia within 3 days.

RESULTS

During the intervention period, 249 of 3402 (7.3%) patients with fractures and cutaneous abscesses were prescribed opioids. The percentage of opioid prescriptions >3 days decreased from 41% to 13.2% (P < .0001), codeine prescription dropped from 1.1% to 0% (P = .09), opioid discharge instructions increased 0% to 100% (P < .0001), and all physicians enrolled in the prescription drug monitoring program. There was no change in return visits for uncontrolled analgesia compared with the baseline (P = .79).

CONCLUSIONS

A comprehensive opioid stewardship program can improve opioid prescribing practices of ED physicians and deliver information on safe storage and disposal of prescription opioids with a negligible effect on return visits for uncontrolled pain.
Stiff-person syndrome with sensorimotor polyneuropathy – case report
Authors:   Department of Neurology and Stroke, Medical University of Lodz, Łódź, Poland, Jastrzębski Karol ,   Military Medical Academy University Teaching Hospital, Łódź, Poland,   Specialist Neurological Practice Karol Jastrzębski, Łódź, Poland, Romanowska Nina ,   Military Medical Academy University Teaching Hospital, Łódź, Poland, Rek-Pacześ Marta ,   Military Medical Academy University Teaching Hospital, Łódź, Poland, Kępczyński Łukasz ,   Polish Mother’s Memorial Hospital – Research Institute, Łódź, Poland, Plucińska Agnieszka ,   Military Medical Academy University Teaching Hospital, Łódź, Poland, Gałecka-Kowalska Monika ,   Military Medical Academy University Teaching Hospital, Łódź, Poland, Pacześ Krzysztof ,   Polish Mother’s Memorial Hospital – Research Institute, Łódź, Poland
Published: November 2021

Stiff-person syndrome (SPS) is a rare disorder with an estimated prevalence in the general population of 1–2 cases/1,000,000. It is 2–3 times more common in females, with symptom onset at the age of 20–50 years in most cases. Although stiff-person syndrome is associated with antibodies against glutamic acid decarboxylase and amphiphysin, their presence is not necessary for the diagnosis. The treatment should be multidirectional and include immunomodulation, symptomatic treatment as well as monitoring and treatment of overlapping autoimmune, and surgery. We present a case report of a patient diagnosed with stiff-person syndrome overlapping with axonal and demyelinating sensorimotor polyneuropathy. The diagnostic workup indicated diabetes-related polyneuropathy. About 30% of patients diagnosed with stiff-person syndrome also have diabetes. Polyneuropathy alone is rarely reported to overlap with the disorder. In our opinion, polyneuropathy may have a beneficial effect on the clinical presentation of stiff-person syndrome.
Promoting the future of innovative higher education through thousands of master's programmes
Authors: Feher Katalin , Géring Zsuzsanna , Király Gábor
Published: November 2021

This paper discusses how leading innovative universities and their master's programmes reflect rapidly changing social-economic technological trends. The increasing focus on the STEM subjects, the changing profile of business and MBA programmes, and the ratio of interdisciplinarity provide insights into the development of future-oriented higher education. In the scope of this study, 2,708 master's programmes were surveyed globally based on their online representation, and 1,750 training programmes from this list were analysed in terms of employability rankings. According to our findings, Western Europe offers the largest number of master's programmes. STEM studies are overrepresented at the top innovative universities, and interdisciplinary studies account for fifteen percent of the programmes. Additionally, business studies with interdisciplinary programmes were identified in a higher proportion as compared to business-only studies. The findings signal the labour market's preferences toward future-oriented, personalised and responsive knowledge. The present study contributes to future education through a global analysis, and supports the strategy creation of higher education institutions (HEIs). Therefore, this article is especially informative to representatives, policy makers or researchers at future-oriented HEIs.