bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of Alcohols: Streamlined C1 to Cn Hydroxyalkylation through Photoredox Catalysis
Authors: Pasca Francesco , Gelato Yuri , Andresini Michael , Romanazzi Giuseppe , Degennaro Leonardo , Colella Marco , Luisi Renzo
Published: March 2024

Naturally occurring and readily available α-hydroxy carboxylic acids (AHAs) are utilized as platforms for visible light-mediated oxidative CO2-extrusion furnishing α-hydroxy radicals proved to be versatile C1 to Cn hydroxyalkylating agents. The decarboxylative direct Giese reaction (DDGR) is operationally simple, not requiring activator or sacrificial oxidants, and enables the synthesis of a diverse range of hydroxylated products, introducing connectivity typically precluded from conventional polar domains. Notably, the methodology has been extended to widely used glycolic acid resulting in a highly efficient and unprecedented C1 hydroxyhomologation tactic. The use of flow technology further facilitates scalability and adds green credentials to this synthetic methodology.
Python-Based Interactive RDKit Molecule Editing with rdEditor
Authors: Bjerrum Esben Jannik , Palunas Kovas , Menke Janosch
Published: March 2024

RDKit is a widely used toolkit for cheminformatics, renowned for its fast C++ backend and versatile Python API. However, in many cases, users find themselves needing to create or edit molecules in external programs, as the majority prefer not to manipulate raw SMILES strings. Unfortunately, most available tools for this purpose are either proprietary, deprecated, or not Python-based. Here we introduce rdEditor, a molecular editor entirely written in Python 3 using PySide2 graphical user interface widgets. The application is programmed in an object-oriented fashion, and the custom PySide2 widgets can be easily reused in other applications. It's important to note that this application is an editor, not a drawing program. In other words, RDKit handles the layout of the molecule entirely, and the user interacts with the molecular graph object directly, rather than drawing on a canvas with subsequent conversion to molecular format. While reusing functionality from RDKit contributes to an efficient codebase, there are some drawbacks if end-users expect to have control over the precise placement of atoms. The code is released as open-source and is available on GitHub at: https://github.com/EBjerrum/rdEditor.
PromptSMILES: Prompting for scaffold decoration and fragment linking in chemical language models
Authors: Thomas Morgan , Ahmad Mazen , Tresadern Gary , de Fabritiis Gianni
Published: March 2024

SMILES-based generative models are amongst the most robust and successful recent methods used to augment drug design. They are typically used for complete de novo generation, however, scaffold decoration and fragment linking applications are sometimes desirable which requires a different architecture, a different training dataset and therefore, re-training of a new model. In this work, we describe a simple procedure to conduct constrained molecule generation with a SMILES-based generative model to extend applicability to scaffold decoration and fragment linking by providing SMILES prompts, without the need for re-training. In combination with reinforcement learning, we show that pre-trained, decoder-only models adapt to these applications quickly and can further optimize molecule generation towards a specified objective. We compare the performance of this approach to a variety of orthogonal approaches and show that performance is comparable or better. This approach enables the unification of de novo generation, scaffold decoration, and fragment linking into one chemical language model, without the need to use a bespoke grammar, curate a custom dataset or train a separate model. For convenience, we provide an easy-to-use python package to facilitate model sampling which can be found on GitHub and the Python Package Index.
Determination of Reasons for the Exclusion of Kidney Transplant Candidates from the Organ Offer List
Authors: SOYLU Dilek , SOYLU Ayse , YÜZBAŞIOĞLU Mehmet Fatih
Published: March 2024

Objective: The study aims to determine why kidney transplantation candidates are excluded from the organ offer list.

Materials and Methods: The study was conducted as a retrospective screening of archived records. The data of 228 patients who met the study criteria were included. Evaluations were made concerning sociodemographic characteristics, blood group, dialysis type and time, panel reactive antibody results, duration of waiting for an organ, and the recipient's current status (on the active waiting list, transplanted, or deceased).

Results: Of the candidates on the organ transplantation waiting list, 14.9% could not be contacted at the telephone number in the records, and 6.1% could not attend the centre because of transport problems. A statistically significant difference was determined between the age range, the time since starting dialysis, and the candidate's current status according to the waiting duration.

Conclusion: Through collaboration with dialysis and transplantation centres and the Regional Health Authority, nurses can update the contact telephone numbers and resolve transplant candidates' transport problems, thereby allowing those receiving dialysis treatment to be added to the organ transplantation waiting list without losing time.
Reason for Discontinuing the Drug in Patients Using Statins
Authors: TATAR Sefa , OKTAY İrem , YAVUZ Yunus Emre , ALSANCAK Yakup , SERTDEMİR Ahmet Lütfü , ÇELİK Mustafa
Published: March 2024

Objective: In recent years, there has been a lot of news about the negative effects of statin use on patients. Our study aimed to investigate the reasons for drug discontinuation in patients with indications for statin use.

Materials and Methods: 180 patients who were indicated to start statin treatment for any reason were included in the study. Demographic and clinical characteristics of the patients, cardiovascular disease risk factors, and lipid levels at admission were determined.

Results: It was determined that 81.1% of the patients were started on statin treatment. It was observed that patients using regular medication had lower LDL (low-density lipoprotein) and total cholesterol levels than those who did not use medication regularly (p
Broadening the Discourse on Death Anxiety: Unexplored Dimensions and Holistic Perspectives
Authors: ÖZDEMİR Serdar
Published: March 2024

Understanding death anxiety among patients is crucial for healthcare professionals to provide personalized care and support strategies. Cultural and social norms play a significant role in shaping an individual's perception of death. While some cultures accept death as a natural and cyclical process, others tend to avoid it. Therefore, healthcare professionals must consider these factors to develop effective assistance strategies. This our discourse emphasizes the importance of comprehensively evaluating death anxiety to contribute to the study of Özpancar Şolpan et al. on this subject.
Financial Confidence in Financial Satisfaction Through Financial Behavior for Ciputra School of Business Makassar Students
Authors: Chandra Aldrichnan Aprilio , Manggala Felysia , Phurnama Richard , Karystin Yuyun , Suade Meilisa , Nurfadilah Nurfadilah
Published: March 2024

Financial literacy can lead to financial satisfaction (Henager & Anong, 2014). However, the majority of educated people are less content (Grable, J. E., Britt, S., & Cantrell, J., 2007). A person with greater financial literacy is more likely to excercise caution when making financial decisions and, therefore, less likely to feel confidence with their finances. This is also supported by studies by Hira, Fawslow, and Mugenda (cited in Robb & Woodyard, 2011). This study aims to empirically test the causal relationship of financial confidence and financial satisfaction use in relation to financial behavior. This study is an explanatory study aimed at discovering and explaining the causal relationship between variables (Sujarweni, 2019). The results of the study partially indicate a significant effect of financial satisfaction on financial behavior. Financial satisfaction has a positive relationship with financial behavior, Thus, it is concluded that hypothesis one is supported and tested by data (received) that financial satisfaction has a positive effect on financial behavior.
The Role of Women’s Farmer Groups as An Alternative Solution to Food Insecurity during The Covid -19 Pandemic
Authors: Amalia Fisy , Mayndarto Eko Cahyo
Published: March 2024

Research on the Az Zahra Women's Farmer Group in the Buaran South Tangerang area which was carried out from March 2021 to August 2021 with the title The Role of Women's Farmer Groups as Alternative Solutions to Food Insecurity during the Covid-19 Pandemic in Buaran, Serpong, South Tangerang. The data taken are primary and secondary data, primary data is taken from observations and interviews with officials, supervisors and members of the women's farmer group. The results of environmental observations and interviews conducted can be seen that the group has succeeded in achieving group managerial effectiveness. The results of the observations are seen from the data at the time of the initial formation (in 2018) and the data at the time the research was conducted (in 2021). The initial data for the formation of the Women Farmers Group are: The area of cultivated land is 300m2, with 29 members, 2 types of plants that can be harvested, the value of the harvest is Rp. 1,740,000. a year. While the results of operations in 2021, the number of plants will be 25 types of plants, the area of land being cultivated will be 10,000 m2 and the welfare level of members will be Rp. 12,500,000 a year. In terms of organizational management, this group has proven that it has carried out managerial effectiveness in order to achieve the group's goals as indicated by the increasing area of land planted, growing crop yields and increasing welfare of members although they do not have the land. This group that has performed its management functions well, such as planning, organizing, directing and controlling. The role of the Women Farmers group in preventing food insecurity is very effective, because the harvest obtained can prevent food insecurity in the family as well as the surrounding community by providing food in the form of vegetables and health plants, as well as by making donations to local residents in need.
Camino hacia la Regeneración Humana:
Authors: Jimena Alcaide Jorge
Published: March 2024

Este artículo incluye una contextualización del actual estado de crisis sociopolítica y económica que estamos viviendo a nivel global, generado a consecuencia de la pandemia del Covid-19 y de los enfrentamientos bélicos que actualmente se viven en el este de Europa y en la franja de Gaza. Estas tensiones son el culmen de diversos hitos, como la globalización o el incesante desarrollo tecnológico que, desde los inicios del siglo XXI, nos han ido dirigiendo sin freno hacia un tensionamiento espacio-temporal en diferentes ámbitos de nuestra vida (social, político, económico), y a una situación cada vez mayor de insostenibilidad. La revisión realizada tiene como objetivo establecer un conjunto de líneas maestras para un cambio educativo que priorice un nuevo tipo de formación basada en la educación para una ciudadanía de índole global, que desde la comunicación y el diálogo pueda favorecer un cambio global hacia la mejora. El método de investigación utilizado descansa sobre el análisis del contenido de diversidad de fuentes secundarias, principalmente artículos de investigación, informes de organizaciones internacionales y noticias de prensa, mediante los cuales hemos llegado al establecimiento de las bases para posibilitar este cambio de rumbo social y educativo. Nuestras recomendaciones son incluidas tanto en los temas sometidos a discusión como en las conclusiones y propuestas de mejora que se formulan, a través de las cuales se exige un redireccionamiento hacia un necesario humanismo guiado por parámetros de carácter pedagógico, emancipador y transformador; estos últimos que puedan dirigirnos como sociedad hacia una nueva revolución social que nos salve de, o al menos logre frenar, una anunciada extinción.
Exploring Effective Ways of Green Printing to Reduce Harmful Volatile Organic Compounds Emissions
Authors: Li Yizhe , Wang Yao
Published: March 2024

This paper delves into the transformative shift in the printing industry from traditional petroleum-based inks to sustainable alternatives, focusing on soy ink. Initially, it examines the environmental and health hazards associated with conventional printing, highlighting the detrimental impact of volatile organic compounds (VOCs) and toxic substances in inks. The emergence of soy ink as an eco-friendly solution is then explored. Derived from soybeans, soy ink significantly reduces the release of harmful VOCs and enhances the recyclability of printed materials. The paper discusses not only the environmental benefits of soy ink but also its operational and economic advantages, such as improved deinking capabilities and waste reduction. A notable development in soy ink technology is the use of soy methyl ester, which addresses the challenges of slow drying and penetration associated with traditional inks. The paper concludes by emphasizing the need for continued innovation in sustainable practices within the printing industry, positioning soy ink as a key player in aligning economic goals with environmental responsibility. The shift to soy-based inks exemplifies a broader trend towards sustainability, pivotal for the future health of the planet.
Systematic Risk Analysis of Listed Financial Institutions from the Perspective of Complex Network
Authors: Li Shiyun
Published: March 2024

Based on the complex network theory, this paper studies the systemic financial risks in China’s financial market. According to the industry classification of the China Securities Regulatory Commission in 2012, the daily closing prices of 45 listed financial institutions are collected and the daily return rates of each financial institution are measured according to the logarithmic return rate calculation formula. In this paper, the risk spillover value ΔCoVaR is used to measure the contribution degree of each financial institution to systemic risk. Finally, the relationship between the risk spillover value ΔCoVaR and the node topology index of the risk transmission network is investigated by using a regression model, and some policy suggestions are put forward based on the regression results.
Pemberdayaan Bumdes Bojonegoro Melalui Kemandirian Pengelolaan Website
Authors: Putra, S.E., MSA Rediyanto , Kusumaningtias Rohmawati , Pujiono Pujiono , Siregar Cantika Sari , Hidayat Rendra Arief , Prasetyo Eko
Published: March 2024

Kegiatan pengabdian ini akan dilakukan pada BUMDES yang terletak di Desa Kapas, Kecamatan Kapas Kabupaten Bojonegoro Jawa Timur. Kelompok ini mengalami beberapa masalah yaitu rendahnya pengetahuan tentang penggunaan Teknologi Informasi dan Komunikasi bagi usaha BUMDES dan belum tersedianya media website BUMDES yang dapat digunakan untuk mengelola dan menyebarluaskan informasi kepada publik. Oleh karena itu, kegiatan ini memberikan solusi sebagai berikut pelatihan mengenai penggunaan Teknologi Informasi dan Komunikasi kepada para pengelola BUMDES dan pembuatan website dan akun YouTube sebagai media BUMDES untuk pengelolaan dan penyebaran informasi secara digital. Metode yang digunakan dalam kegiatan pengabdian kepada masyarakat ini adalah survey lapangan, ceramah, demonstrasi, praktik, diskusi, dan penyebaran kuesioner. Kegiatan PkM ini telah berjalan dengan baik yang ditunjukkan dari hasil survei kegiatan PkM yang telah diberikan kepada peserta. Kegiatan PkM ini berhasil memberikan sejumlah luaran yang diberikan ke mitra berupa produk website, akun youtube, dan aplikasi keuangan sederhana berbasis excel. Selain itu, PkM ini juga memberikan mitra ilmu pengetahuan yang dapat digunakan untuk mengelola usaha BUMDES yang telah dijalankan agar menjadi lebih baik lagi.
PENINGKATAN SOSIOEKONOMI MASYARAKAT MELALUI PELATIHAN DISPLAY TOKO BAGI GALERI UMKM TP PKK KABUPATEN LUMAJANG
Authors: Fahrullah A’rasy , Yasin Ach . , Ridlwan Ajib , Fikriyah Khusnul , Indrarini Rachma , Anwar Moch. Khoirul
Published: March 2024

Usaha Mikro Kecil Menengah atau biasa disebut UMKM merupakan salah satu penggerak roda perekonomian di Indonesia khususnya di kabupaten lumajang. Meningkatnya jumlah UMKM dari tahun ke tahun menunjukkan bahwa mayoritas masyarakat di lumajang  mulai berkeinginan untuk membuat bisnisnya sendiri. Namun kendala yang sering dihadapi oleh pelaku usaha di lumajang adalah kurangnya kemampuan mereka dalam mendispaly produknya. Pengetahuan yang rendah mengenai display produk menjadi masalah tersediri dan berdampak pada nilai produk yang rendah dan kurang diminati. Untuk mengatasi hal tersebut dilakukan pelatihan display produk. Metode yang digunakan adalah pelatihan yang disampaikan secara luring. Hasil dari kegiatan ini berupa peningkatan pengetahuan dan kemampuan peserta dalam mendisplay produk. Hal ini diketahui dari respon peserta pada kuesioner yang diberikan yang menunjukkan hasil bahwa seluruh peserta setuju bahwa materi yang diberikan bermanfaat dan berdampak pada peningkatan pengetahuan peserta
Pendampingan Pendaftaran Nomor Induk Berusaha (NIB) pada UMKM Brownis D’Morena Kelurahan Gununganyar
Authors: Bayu M Rizky Bayu Pratama , Wikartika Ira
Published: March 2024

Usaha Mikro, kecil dan menengah atau UMKM merupakan kategori bisnis yang mencakup skala kecil hingga menengah dalam hal prodeuksi, omset ataupun tenaga kerja. UMKM menjadi tulang punggung yang menunjang perkembangan perekonomian negara. UMKM menjadi salah satu faktor pembangkit ekonomi dengan menyediakan lapangan kerja sendiri, sehingga dapat mengurangi angka pengangguran dan kemiskinan di indonesia. Namun salah satru faktor yang harus diperhatikan ketika mendirikan sebuah usaha merupakan legalitas usaha, para pelaku UMKM harus terdaftar secara resmi di pemerintahan dan memiliki surat izin berusaha, jenis legalitas usaha yang paling tidak harus dimiliki adalah sertifikat Nomor Induk Berusaha, pendaftaran NIB sendiri dapat dilakukan melalui website Online Single. Dengan memiliki Sertifikat Nomor Induk Berusaha, maka usaha tersebut telah secara resmi terdaftar dipemerintahan. Adapun manfaat memiliki Nomor Induk Berusaha adalah memperoleh perlindungan hukum serta mempermudah akses keuangan karena banyak lembaga keuangan yang menjadikan NIB sebagai syarat untuk mengajukan pinjaman modal. Oleh karena itu mahasiswa UPN veteran Jawa timur yang mengikuti program Bina desa dikelurahan Gununganyar, surabaya memiliki inisiatif untuk melakukan pendampingan dan sosialisai kepada UMKM kelurahan gununganyar, salah satunya adalah usaha Brownies D’morena untuk mendapatkan sertfikat NIB dengan tujuan meningkatkan kesejahteraan UMKM.
Inovasi Produk Herbal Telang Panjare Untuk Peluang Usaha Warga Kelurahan Gunung Anyar
Authors: Yudha Tengku Sandi Yudha , Soebiantoro Ugy
Published: March 2024

The butterfly flower, usually call the Telang flower, is a type of plant that grows like beans and has purple leaves. Butterfly pea flowers contain anthocyanin compounds, so when used as a solvent, they produce a purple color in food products. The anthocyanin compounds used as natural dyes also have antioxidant properties, which function to ward off free radicals and prevent premature aging and degenerative diseases. In this activity, the community RW1 Gunung Anyar Village, especially the KSH Cadres, were accompanied and given counseling regarding the manufacture and benefits of Telang Panjare Syrup, which can be used as a business opportunity by developing innovative products that can increase the sales value of consumer herbal drinks and create new market share so that this product can become a sustainable business. Panjare Telang Syrup is a beverage product made from herbal ingredients made from Telang flowers, which have a characteristic blue color. Also, the blue color dissolves in water, so the packaging looks attractive. UPN's "veteran" East Java village development team saw a business opportunity and experimented with producing Terang He Panjare His syrup. This idea was finally implemented well in socialization activities with the theme "Business Management Strategies for MSMEs."
Pelatihan Pegembangan Produk dan Teknik Pemasaran Pada Peternak Lebah Madu Kelulut
Authors: Eriawaty Eriawaty , Rahman Rahman , Putra Kharisma Nugraha , Sintani Dea , Hariansono Hendry Wahyu
Published: March 2024

Kegiatan pelatihan pengembangan produk dan teknik pemasaran pada peternak lebah madu kelulut ini bertujuan untuk menambah pengetahuan dan keterampilan bagi masyarakat, dengan melihat begitu besarnya potensi di kelurahan Kereng Bengkirai yang dapat dikelola oleh masyarakat sekitar sebagai sumber penghasilan. Metode yang digunakan dalam kegiatan pengabdian masyarakat ini yaitu partisipatif. Melalui pendekatan yang difokuskan pada peningkatan peran masyarakat secara aktif dalam proses pelatihan yang diberikan. Teknik pelatihan dilakukan secara bervariasi melalui ceramah, tanya jawab, dan demonstrasi. Teknik pengumpulan data dilakukan dengan observasi, wawancara, serta dokumentasi. Hasil pelatihan yang telah dilakukan menunjukan adanya peningkatan pengetahuan dan keterampilan masyarakat mulai dari pengembangan budidaya lebah hingga pemasaran hasil pengelolaan madu dari lebah tersebut.
Pengenalan Manajemen Investasi dan Pasar Modal Bagi Masyarakat Migran Indonesia Di Malaysia
Authors: Bhilawa, SE, Ak, M.Si, CA Loggar , Hariyati Hariyati , Satyawan Made Dudy , Laksono Bayu Rama
Published: March 2024

Tujuan dari kegiatan pengabdian ini adalah untuk memberikan edukasi dan pendampingan kepada masyarakat khususnya warga Indonesia yang bermukim di Malaysia akan pentingnya menginvestasikan sebagian pendapatan mereka miliki dan memberikan pelatihan edukasi tentang salah satu bentuk investasi yaitu pasar modal. Artinya sekembalinya dari perantauan PMI dapat menjadi wirausaha dan mengembangkan ekonomi keluarga secara mandiri. Walaupun modal yang diperoleh telah cukup, tanpa dorongan keluarga dan keterampilan pengelolaan keuangan yang cukup tidak akan mendorong para PMI untuk tidak kembali merantau. Keterampilan membangun usaha dengan melihat potensi, peluang, modal, manajemen dan prospek yang baik akan sangat dibutuhkan bagi para PMI di tanah air, Perencanaan keuangan yang kuat dan keterampilan pengelolaan yang memadai membuat kendala dalam pengembangan untuk jangka panjang dalam hal keuangan dapat termitigasti secara optimal. Target khusus melalui pendampingan dan pelatihan ini diharapkan masing-masing mitra akan dapat mengetahui pentingnya berinvestasi dibandingkan menabung, mengubah paradigm saving society menjadi investment society, dan menjadi investor individu untuk meningkatkan kekayaan dan ekonomi keluarga mitra di masa depan. Metode yang akan dipakai dalam pencapaian tujuan tersebut adalah tutorial, pelatihan pengenalan pasar modal serta pelatihan dan pendampingan cara bertransaksi saham, memilih saham, bagaimana menentukan saham yang baik dan buruk, strategi bertransaksi saham, serta menjaga kestabilan psikologis seorang investor individu.

Kata Kunci: investasi, pasar modal, pendampingan, PMI, Malaysia
Cooperação militar e fronteiras na Amazônia: O caso do Brasil e da Colômbia
Authors: Medeiros Filho Oscar
Published: March 2024

O presente artigo se propõe a analisar os desafios militares e as oportunidades de cooperação em áreas fronteiriças, tendo como estudo de caso a fronteira entre o Brasil e a Colômbia. A hipótese defendida é a de que, diante do desafio do exercício pleno da soberania territorial e de demandas por gestão compartilhada desses territórios fronteiriços, tem-se constituído em um considerável canal de cooperação e de confiança mútua entre militares dos dois países. Para tanto, o artigo está dividido em cinco seções. A primeira é uma breve introdução sobre o tema. A segunda analisa as peculiaridades relacionadas à fronteira entre Brasil e Colômbia e suas implicações para as questões de defesa e segurança. A terceira seção discute as dinâmicas territoriais e os desafios militares naquela fronteira. A quarta seção discute elementos da cooperação entre os dois países na área de fronteira com destaque para os conceitos de vizinhança e cooperação militar. Por fim, são apresentas breves considerações finais.
Cooperação policial internacional transfronteiriça: o caso do Amapá e da Guiana Francesa
Authors: Correa Paulo Gustavo Pellegrino , Farias Borges Carlos Alberto
Published: March 2024

O objetivo deste artigo é avaliar a atuação do Centro de Cooperação Policial (CCP) em suas ações de cooperação policial internacional que ocorrem na fronteira franco-brasileira. A cooperação policial transfronteiriça entre Brasil e a França através do Amapá e da Guiana Francesa ocorre desde 2010, com a criação e entrada em funcionamento do CCP na cidade de Saint-Georges, na Guiana Francesa. O CCP tem como objetivo a troca de informações entre os órgãos de segurança pública da fronteira de forma ágil, segura e com amparo legal em a cordostratados internacionais. As ações de integração e cooperação envolvem altos investimentos em recursos públicos: recursos humanos, financeiros, materiais, etc. Nesse contexto, emerge a seguinte questão da pesquisa: ao longo destes dez anos de cooperaçãopolicial internacional, como se deu a contribuição do Centro de Cooperação Policial para o enfrentamento da criminalidade transfronteiriça? Trata-se de uma pesquisa aplicada, exploratória e descritiva, de abordagem qualiquantitativa, coletando dados no período de 2010 a 2019. A pesquisa documental foi realizada por meio da análise de documentos conservados em órgãos públicos que fazem parte do CCP: no Brasil, Polícia Federal; na Guiana Francesa, junto à Polícia de Fronteiras (PAF) e na Gendarmerie Nationale, tendo o Centro de Cooperação Policial de Saint-Georges como mediador do acesso aos dados internacionais
Mapemaneto das iniciativas sobre segurança na fronteira do Brasil e do Paraguai
Authors: Guimarães Vaz Luísa , De Franciscis Ramos Carlos Eduardo
Published: March 2024

O presente trabalho tem como objetivo mapear as iniciativas legais e operativas sobre segurança na fronteira no Brasil e no Paraguai e analisar a assimetria legal, institucional, econômica e de desenvolvimento existente entre ambos países a fim de pontuar como essa questão afeta a região analisada. Para isto, será realizada uma a revisão de literatura de fonte primária, sendo o mapeamento em questão, e uma revisão de literatura de fonte secundária, que trabalha a teoria, os conceitos e a conjuntura da fronteira Brasil-Paraguai. No primeiro momento, visualiza-se que essa assimetria dificulta a cooperação regional no combate ao crime organizado transnacional na região, tornando-a, cada vez mais, terreno fértil para as atividades ilícitas como o tráfico de armas, drogas e contrabando. Por fim, espera-se que o trabalho possa contribuir para os estudos de defesa bem como os de segurança nacional, regional e, consequentemente, internacional, dessa forma, contribuindo para os Estudos de Segurança.

Palavras-chaves: Crime organizado transnacional; Estudos de Segurança; Fronteira; Segurança nacional.
Projetos de defesa e spin-offs no Brasil: uma análise dos efeitos do Projeto F-X2
Authors: Correa Gilberto Mohr , Soto Urbina Ligia Maria
Published: March 2024

O investimento na defesa é frequentemente justificado pelo impacto positivo, tanto tecnológico quanto econômico, que a base industrial de defesa exerce sobre o desenvolvimento nacional. Essa premissa está ligada à expectativa de que as tecnologias originadas no âmbito militar possam se transferir para aplicações civis, fenômeno conhecido como spin-off. Entretanto, a divergência de perspectivas em correntes de pesquisa sobre o real impacto dos spin-offs, mantém a questão controversa. Esta pesquisa tem como objetivo examinar empiricamente a ocorrência de spin-offs no contexto contemporâneo brasileiro. Para isso, um estudo de caso é delineado para avaliar os spin-offs resultantes do Projeto F-X2, relacionado à aquisição de aeronaves de caça. O Projeto F-X2, com sua tecnologia avançada, oferece uma oportunidade singular para avaliar os spin-offs no Brasil. O estudo baseia-se em referencial teórico sobre transferência de tecnologia e transbordamento de conhecimento, além de análises de spin-offs em contextos internacionais e nacionais. Os resultados indicam spin-offs localizados em atividades tecnológicas de empresas envolvidas no F-X2, porém sem impactos significativos em outros setores da economia.
PENGARUH KUALITAS PELAYANAN TERHADAP KEPUASAN PELANGGAN J&T EXPRESS DROP POINT TAKKALALA DI KECAMATAN LILIRILAU KABUPATEN SOPPENG
Authors: Aprilia Tasia
Published: March 2024

Penelitian ini mengkaji tentang pengaruh kepuasan pelanggan terhadap kualitas pelayanan J&T Express. Tujuan penelitian ini adalah untuk mengetahui gambaran kualitas pelayanan pada jasa pengiriman J&T Express, untuk mengetahui tingkat kepuasan pelanggan pada jasa pengiriman J&T Express, dan untuk mengetahui pengaruh kepuasan pelanggan terhadap kualitas pelayanan J&T Express. Pendekatan penelitian ini adalah kuantitatif dengan metode penelitian korelasional. Penelitian ini dilaksanakan di Kecamatan Lilirilau Kabupaten Soppeng. Sumber data dalam penelitian adalah pelanggan J&T Express Drop Point Takkalala pada bulan April sampai Juni 2021. Teknik pengumpulan data berupa observasi, wawancara, dan kuesioner. Teknik analisis data berupa uji normalitas, analisis deskriptif, analisis regresi linier sederhana, uji T, analisis koefisien korelasi, dan analisis koefisien determinasi. Hasil penelitian menunjukkan bahwa indikator yang digunakan pada setiap variable tersebut menunjukkan dimana kualitas pelayanan berada pada kategori sangat baik. Indikator pada variabel kepuasan pelanggan berada pada kategori sangat baik. Berdasarkan uji korelasi terjadi hubungan yang sangat tinggi diantara kedua variable tersebut. Dapat disimpulkan bahwa terdapat pengaruh yang signifikan antara kealitas pelayanan terhadap kepuasan pelanggan J&T Express Drop Point Takkalala di Kecamatan Lilirilau Kabupaten Soppeng.
Pengaruh Online Custumer Review dan Rating terhadap Kepercayaan Pembelian Produk Kecantikan pada Online Shop Shopee (Studi pada Konsumen Perempuan di Kota Makassar)
Authors: Afif Qalby , Akib Haedar , Baharuddin Aris
Published: March 2024

Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh online Costumer review dan rating terhadap Kepercayan pembelian Produk kecantikan pada online Shop Shopee baik secara simultan maupun secara parsial dimana Konsumen Perempuan di Kota Makassar menjadi objek Penelitiannya. Penelitian ini menggunakan metode penelitian kuantitatif. Teknik pengumpulan data yang digunakan adalah melalui pengumpulan data primer (kuisioner dan observasi) dan pengumpulan data sekunder (kajian pustaka dan dokumentasi). Sampel yang digunakan yaitu sampel yang dirumuskan oleh Slovin dengan tingkat kepercayaan 90 persen sampel, yaitu sebanyak 100 Responden. Data diperoleh dari hasil penelitian yang diolah dengan menggunakan analisis data dan menggunakan bantuan program perangkat lunak SPSS versi 25 yang terdiri dari uji validitas, reliabilitas terhadap instrumen  Penelitian serta teknik analisis data deskriptif dan analisis statistik inferensial terhadap data yang telah diperoleh.Hasil penelitian menunjukkan bahwa indikator yang digunakan untuk setiap variabel menunjukkan bahwa variabel online Costumer Review dan rating berpengaruh secara signifikan terhadap Keprcayaan pembelian Konsumen produk kecantikan pada belanjan Online di marketplace Shopee. Hal itu dibuktikan Berdasarkan uji korelasi serta uji T dan Uji F serta uji Kofisien Determinasi terhadap data yang telah diperoleh.
Pengaruh Selebgram Endorsement Terhadap Minat Beli Produk Kuliner di Kota Makassar
Authors: Saputrakarim Khaerul , S Muh Rizal , Baharuddin Aris
Published: March 2024

Penelitian ini bertujuan untuk mengetahui, Pengaruh Selebgram Endorsement terhadap Minat Beli produk kuliner di Kota Makassar. Variabel bebas dalam penelitian ini adalah selebgram endorsement dengan indikatornya dapat dipercaya, keahlian, daya tarik, rasa hormat, dan kesamaan. Sedangkan variabel terikatnya adalah minat beli dengan indikatornya adalah perhatian, ketertarikan, keinginan, keyakinan, dan tindakan. Untuk mencapai tujuan penelitian tersebut maka peneliti menggunakan teknik pengumpulan data melalui kuesioner dan dokumentasi. Sampel yang digunakan dalam penelitian ini adalah pengikut akun instagram @fadelaustyn yaitu sebanyak 100 akun instagram yang telah diambil dengan menggunakan rumus slovin. Data yang telah diperoleh dari hasil penelitian diolah dengan menggunakan analisis kuantitatif dengan menggunakan aplikasi SPSS 25 yang terdiri dari uji validitas dan reliabilitas, analisis data deskriptif, dan analisis statistik inferensial. Hasil penelitian menunjukkan bahwa indikator yang digunakan pada setiap variabel yang menunjukkan bahwa variabel selebgram endorsement berada pada kategori sangat baik dan variabel minat beli berada pada kategori baik. Berdasarkan dengan uji korelasi terjadi hubungan sangat tinggi diantara kedua variabel tersebut. Sehingga dapat disimpulkan bahwa terdapat pengaruh antara selebgram endorsement terhadap minat beli produk kuliner di kota Makassar.
ENVIRONMENTAL DISCOURSE AFTER THE ENVIRONMENTAL TURN. UN CLIMATE CONFERENCES
Authors:   independent researcher, Kuleshova Anastasia A.
Published: March 2024

The article is devoted to the analysis of modern environmental discourse in the global public space. Multilateral conferences on environmental issues are becoming a recognized platform with a high degree of conventionality and legitimacy. The article examines elements and markers that make it possible to judge the value foundations of discursive statements and the relationships that arise between subjects. Studies of environmental discourse, conducted in the humanities from the perspective of an environmental cognitive turn, make it possible to present the complexity of modern public ideas about nature and man and form a new view on the content of discussions about the environment in the public field.
Developing an intervention to manage professional isolation among emergency nurses working in Lesotho: an action research approach.
Authors:   , Kutoane Mahlomola
Published: March 2024

Introduction: Professional isolation is described as a deficiency in one’s network of social relations at work and is associated with compromised health service delivery and quality of life among health professionals, particularly those working in low-resource environments. Aim: to develop an intervention for managing professional isolation among emergency nurses working in Lesotho. Method: A mutually collaborative action research study, with an exploratory-descriptive qualitative design, was conducted in the emergency departments of five selected hospitals in Lesotho, with 25 purposively sampled registered nurses. A needs assessment was conducted through a scoping review and focus group discussions, followed by the establishment of a three-member research team (Cycle One). Thereafter, 13 individual interviews were conducted to explore the perceptions of professional isolation among emergency nurses (Cycle Two). The intervention, a Digital Community of Practice, was developed (Cycle Three) and facilitated through WhatsApp platform, then was implemented and evaluated in Cycle Four. Results: The scoping review highlighted there is limited literature on professional isolation among health professionals and the focus group discussions revealed that participants acknowledged that there was a need for such a study. Qualitative interviews exploring professional isolation resulted in an overarching theme of ‘feeling like an island’ and three categories; lack of interprofessional collaboration and consultation, skills mismatch, and enforced loneliness. Following consultation with the research team, a digital community of practice was developed for emergency nurses using the WhatsApp platform and then implemented. Conclusion This study revealed that emergency nurses in Lesotho do experience professional isolation and a digital community of practice developed using social media, such as WhatsApp, as a communication tool, could be considered as an intervention strategy for managing professional isolation among emergency nurses working in low-resource environments. However, it is recommended that a larger-scale study be undertaken to encourage the motivation for developing contextual interventions for addressing professional isolation in emergency care settings.
Molecular mechanisms of regulation of anthocyanine biosynthesis, photosynthesis, and frost resistance of winter wheat seedlings treated with the 5-aminolevulic acid
Authors: Averina N. G. , Savina S. M. , Yemelyanava A. V. , Dremuk I. A. , Prischepchik Yu. V.
Published: March 2024

It was found that in anthocyanin-enriched coleoptiles of winter wheat EtW5 variety, the exogenous 5-aminolevulinic acid (ALA) increased the content of anthocyanins by a factor of 1.5 and the expression level of structural (PAL, CHS) and regulatory (PAP-1) genes of the anthocyanin biosynthesis pathway. In coleoptiles of Vladi plants containing 33 times less anthocyanins compared to EtW5, the expression of CHS and PAP-1 was reduced and additionally inhibited by ALA. Thus, the genetic activity of the phenylpropanoid and flavonoid sites of the anthocyanin biosynthesis pathway shows distinct variety specificity and a dependence on the level of anthocyanins. ALA significantly reduced the thermal dissipation of excitation energy in PSII complexes in the EtW5 variety enriched with anthocyanins and significantly increased the level of these processes in the Vladi variety. Variety-specificity was noted in the levels of frost resistance of two varieties – high (88 % of surviving plants exposed to a temperature of –8 °С for 5 hours) in the EtW5 variety and lower (80 %) in the Vladi variety. ALA increased the frost resistance of both varieties due to an increase in the content of anthocyanins and proline in the coleoptiles of the EtW5 variety and a higher proline content in the Vladi variety.
Cannulated prolactin test in the diagnosis of the hyperprolactinemia syndrome
Authors: Karlovich N. V. , Shishko O. N. , Malyshko M. A. , Yurenya E. V. , Mokhort T. V.
Published: March 2024

Hyperprolactinemia (HP) is a persistent pathological increase in a prolactin serum concentration amounting to more than 20 ng/ml in males and 25 ng/ml in females and leads to developing the pathological symptom complex of HP primarily from the reproductive system. To confirm the persistent etiology of HP and to eliminate physiological short-term hormone enhancement, a number of recommendations, including Russian and Belarusian, were proposed to make several prolactin measurements.

This study included 120 patients with HP (96 females, 78.0 %) and (27 males, 22.0 %) aged 18–50 years who sought medical help at the Health Institution “Minsk City Clinical Endocrinology Center” in the period from December 2022 to September 2023. After catheterizing the vein, a venous cannula was inserted and blood was taken immediately after cannulating (T0), and then in 60 minutes (T1) and 120 minutes (T2). The cannulated prolactin test results were considered positive – with HP remaining in all three samples (T0, T1, T2), questionable – if HP was kept at T0 and T1, and negative if HP was only at T0. When evaluating the cannulated test results, true HP is 36.7 %. Patients with a positive cannulated test had a higher prolactin at T0, which was 888.5 mME/L (U = 97.0; z = 7.92; p < 0.001). Patients with stress-induced HP (negative test) and patients with true HP (positive test) had no statistically significant differences in age and occurrence frequency of specific and non-specific complaints and symptoms for HP.
Variant models for the development of large-scale agroindustrial enterprises, taking into account their specialization and location
Authors: Artyushevsky N. , Gusakov E. , Rusakovich A. , Bashko D.
Published: March 2024

The scientific and practical significance of the our variants models lies in the development of tools that allow assessing the effectiveness of using the production potential of a large-scale agroindustrial enterprise, justifying cost standards as indicators of planning target indicators, when developing measures to reduce cost intensity. The presentes variable models will be used in assessing the achieved level of use of production potential, for comparative analysis, as well as for shortand long-term planning agroindustrial complex organizations.
The Verbal Influence of Husband and Wife on The Verbal of Couple and Children in The Family
Authors: Defina Defina
Published: March 2024

Interaction among family members can be in the form of verbal interaction. A bad verbal partner has an impact on verbal in the family. The purpose of this study was to examine the relationship and test the influence of family characteristics, husband-wife verbal, on partner and child verbal. This study used a cross-sectional design. The population of this research is husband/wife in Indonesia. The number of respondents was 113 people. The results show that the income of one husband and wife has a significant positive relationship with verbal affection for their partner and their children. Verbal violence of one partner has a significant positive relationship with verbal abuse of their children. A husband/wife's verbal affection for a partner has a significant positive relationship with verbal affection for children. Respondents' verbal violence to their partners had a significant positive effect on verbal violence toward children. Respondents' verbal affection for their partner has a significant positive effect on verbal affection for children. The negative diction used is stupid, and the positive meaning is dear. In conclusion, husband/wife's verbal relationship and influence on their verbal to their children.
PELATIHAN TEKNOLOGI PENGOLAHAN PAKAN KOMPLIT BERBASIS GREEN PROTEIN LOKAL SERTA MANAJEMEN AGRIBISNIS UNTUK MENINGKATKAN PRODUKTIVITAS SUSU KAMBING
Authors: Sukarne  , Sutaryono Yusuf Akhyar , Fahrullah  , Nursan Muhammad
Published: March 2024

Program pengabdian ini dilatarbelakangi oleh melimpahnya sumber pakan hijauan lokal dari jenis leguminosa yang sangat potensial untuk dikreasikan menjadi pakan kambing penghasil susu. Beberapa jenis hijauan yang dimaksud adalah: Turi (Sesbania grandiflora), Lamtoro (Leucaena leucocephala) dan limbah kulit nanas yang kaya nutrisi. Di sisi lain, permasalahan rendahnya suplai nutrisi di masyarakat pedesaan menjadi isu penting penyebab stunting. Sedangkan, sudah dimaklumi bahwa susu kambing sangat potensial sebagai sumber protein hewani bagi masyarakat. Pengabdian ini bertujuan untuk memberikan pendampingan pembuatan dan penerapan pakan komplit kaya nutrisi berbasis protein hijau. Tujuan berikutnya adalah menata manajemen agribisnis yang masih belum berjalan secara optimal. Mulai dari manajemen tim hingga manajemen produksi. Metode pelaksanaan menggunakan Participatory Rural Appraisal (PRA) dengan menjadikan CRF sebagai tempat pelaksanaan pendampingan penerapan pakan komplit dan melibatkan masyarakat mitra CV. CRF sebanyak 20 orang untuk mendapatkan manfaat dari program. Tahapan kegiatan meliputi tahap persiapan, pelaksanaan dan evaluasi kegiatan. Hasil kegiatan pengabdian menunjukkan bahwa adanya peningkatan pengetahuan dan keterampilan masyarakat dalam memahami dan membuat pakan komplit untuk meningkatkan produktivitas susu kambing. Hal ini ditunjukkan dari keterlibatan mereka secara aktif dalam proses pembuatan pakan serta peningkatan pengetahuan berdasarkan pengolahan hasil pre-test dan post-test. Berdasarkan hasil percobaan pakan pada ternak kambing juga diperoleh data peningkatan sebanyak 200 ml/ekor. Sebelumnya ternak kambing yang menjadi materi demplot hanya menghasilkan susu 500 ml/ekor meningkat menjadi 700ml/ekor). Pengetahuan dan keterampilan tentang manajemen agribisnis ternak kambing perah yang lebih efektif dan efisien menjadi bertambah setelah mengikuti kegiatan pengabdian.
PELATIHAN PENYUNTIKAN, PEMANENAN DAN PENANGANAN PASCAPANEN GAHARU PADA Gyrinops versteegii DI PUYUNG, LOMBOK TENGAH
Authors: Mulyaningsih Tri , Muspiah Aida , Hidayati Ernin , Julisaniah Nur Indah , Nadia Ahsanu , Hamidia Baiq Zulifa , Pradita I Made Nanda , Ibadurahman Lalu Faqih , Adhawati Laela , Prazali Arianteza , Sunarwidhi Anggit L. , Takamatsu Sakura , Supiatin
Published: March 2024

Secara alami gaharu diproduksi oleh pohon   gaharu yang mengalami luka atau terinfeksi jamur. Agar pohon gaharu sehat dapat menghasilkan gubal gaharu harus ada perlakuan khusus: seperti perlukaan, memasukan bakteri atau jamur penyebab atau agensia kimia. Tujuan kegiatan ini memberi pengetahuan dan ketrampilan kepada masyarakat yang memiliki pohon  ketimunan (Gyrinops versteegii)  siap suntik di Desa Puyung, Kecamatan  Jonggat, Lombok Tengah, dalam menginokulasi, memanen, mengolah  pasca panen gaharu. Pelaksanana “Pengabdian Pada Masyarakat” terbagi menjadi 2 periode, yaitu: periode 1: penyuntikan dan periode 2: pemanenan dan penanganan pasca panen. Metode penyuntikan pohon ketimunan digunakan dengan metode cairan fermentasi jamur penyebab (CFJP), yang dilaksanakan pada tanggal 19 Februari 2023. Masa inkubasi infeksi sekitar 6 bulan. Pelatihan periode 2: pelatihan pemanenan dan pengolahan pasca panen dilakukan 6 bulan setelah penyuntikan. Pemanenan dilakukan pada ranting yang berdiameter 2,5 cm, sebagai contoh pengolahanan pasca panen. Pelatihan dan praktek pemanenan gaharu dan penangannya pasca panen pada tanggal 17 September 2023. Masyarakat yang telah memiliki pohon gaharu siap suntik mendapatkan pengetahuan dan ketrampilan tentang pemilihan pohon yang telah siap disuntik, membuat pola lubang suntik dan membuat lubang inokulasi serta cara melakukan inokulasi pada batang dan cabang pohon G. versteegii. Selain itu masyarakat juga mendapatkan pengetahuan dan ketrampilan tentang pengecekan batang yang telah siap dipanen, cara pemanenan dan cara penanganan pasca panen gaharu, cara pengklasifikasian gaharu serta cara pemasaran gaharu. Dengan diperolehnya penngetahuan dan ketrampilan cara produksi gaharu dan pemasarannya, masyarakat menjadi terpacu menjadi influenser dalam konservasi gaharu secara ex-situ di kebun dan pekarangannya sendiri.