bluuebunny/crossref_metadata_2025 huggingface dataset:
Suppl. Fig. 1: Experimental design. from Combined PET Imaging of the Inflammatory Tumor Microenvironment Identifies Margins of Unique Radiotracer Uptake
Authors: Zinnhardt Bastian , Pigeon Hayet , Thézé Benoit , Viel Thomas , Wachsmuth Lydia , Fricke Inga B. , Schelhaas Sonja , Honold Lisa , Schwegmann Katrin , Wagner Stefan , Faust Andreas , Faber Cornelius , Kuhlmann Michael T. , Hermann Sven , Schäfers Michael , Winkeler Alexandra , Jacobs Andreas H.
Published: March 2023

Gli36dEGFR cells were implanted. Thereafter, two imaging sequences were conducted: In sequence 1, T2w MRI and PET with [18F]DPA-714 was performed, while [18F]BR-351 PET and [18F]FET PET were conducted at day 13 and 14, respectively. In imaging sequence 2, T2w MRI and [18F]FET PET were conducted at day 12, followed by [18F]BR-351 and [18F]DPA-714 at day 13 and 14, respectively. After the last imaging experiment, mice were sacrificed and the brains immediately harvested for further analysis.
Supplementary Figure S2 from Myeloid Cells That Impair Immunotherapy Are Restored in Melanomas with Acquired Resistance to BRAF Inhibitors
Authors: Steinberg Shannon M. , Shabaneh Tamer B. , Zhang Peisheng , Martyanov Viktor , Li Zhenghui , Malik Brian T. , Wood Tamara A. , Boni Andrea , Molodtsov Aleksey , Angeles Christina V. , Curiel Tyler J. , Whitfield Michael L. , Turk Mary Jo
Published: March 2023

Tumor size comparisons between group.
Figure S3 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Authors: Grossberg Aaron J. , Vichaya Elisabeth G. , Christian Diana L. , Molkentine Jessica M. , Vermeer Daniel W. , Gross Phillip S. , Vermeer Paola D. , Lee John H. , Dantzer Robert
Published: March 2023

This file contains correlations between wheel running and each of tumor volume and plasma IL-6 levels. Also, inflammasome and IL-1 response genes in the brain and liver are presented here.
Supplementary Figure S4 from LSD1 Stimulates Cancer-Associated Fibroblasts to Drive Notch3-Dependent Self-Renewal of Liver Cancer Stem–like Cells
Authors: Liu Chungang , Liu Limei , Chen Xuejiao , Cheng Jiamin , Zhang Heng , Zhang Chengcheng , Shan Juanjuan , Shen Junjie , Qian Cheng
Published: March 2023

SIRT1 is an important histone deacetylase for regulates LSD1 expression and stability.
Supplementary Figure S3 from LSD1 Stimulates Cancer-Associated Fibroblasts to Drive Notch3-Dependent Self-Renewal of Liver Cancer Stem–like Cells
Authors: Liu Chungang , Liu Limei , Chen Xuejiao , Cheng Jiamin , Zhang Heng , Zhang Chengcheng , Shan Juanjuan , Shen Junjie , Qian Cheng
Published: March 2023

Lysine acetylation modification in LSD1 protein.
Figure S6 from Mutational Mechanisms That Activate Wnt Signaling and Predict Outcomes in Colorectal Cancer Patients
Authors: Hankey William , McIlhatton Michael A. , Ebede Kenechi , Kennedy Brian , Hancioglu Baris , Zhang Jie , Brock Guy N. , Huang Kun , Groden Joanna
Published: March 2023

Predictive Value for Candidate Genes.
Figure S6 from Inhibition of Translesion DNA Synthesis as a Novel Therapeutic Strategy to Treat Brain Cancer
Authors: Choi Jung-Suk , Kim Casey Seol , Berdis Anthony
Published: March 2023

Dose response curves for 3-Eth-5-NIdR against U87 cells.
Figure S1 from Inhibition of Translesion DNA Synthesis as a Novel Therapeutic Strategy to Treat Brain Cancer
Authors: Choi Jung-Suk , Kim Casey Seol , Berdis Anthony
Published: March 2023

Plots showing the cell killing effects of 5-NIdR and TMZ alone and in combination in two glioblastoma cell lines (A172 and SW1088).
Movie 5 from Spatial Heterogeneity and Evolutionary Dynamics Modulate Time to Recurrence in Continuous and Adaptive Cancer Therapies
Authors: Gallaher Jill A. , Enriquez-Navas Pedro M. , Luddy Kimberly A. , Gatenby Robert A. , Anderson Alexander R.A.
Published: March 2023

Comparing CT, AT1, and AT2 treatment schedules for a heterogeneous sensitive tumor when cells can migrate. Tumors were initialized by a normal distribution with a mean sensitivity s=100% and standard deviation Ïƒs=25%.
Figure S5_S6 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
Authors: Singh Priyanka , Jenkins Laura M. , Horst Ben , Alers Victoria , Pradhan Shrikant , Kaur Prabhjot , Srivastava Tapasya , Hempel Nadine , Győrffy Balázs , Broude Eugenia V. , Lee Nam Y. , Mythreye Karthikeyan
Published: March 2023

Figure S5: Representative western blot of 6 hr serum starved HMEC-1 cells treated with CM from either shControl or shINHA SKOV3 cells. Anti-INHA (polyclonal; 10 µg/ml; #sc22048, Santa Cruz) antibody was used as indicated. Samples were immunoblotted for phospho-Smad1/5, total Smad1/5 and GAPDH. Quantitation from two independent trials is presented (right graph). Figure S6: (i) Western blotting of lysates from HMEC-1 (above) or MEECs (below) incubated with recombinant 20pM Inhibin A for indicated times or increasing doses of recombinant Inhibin A as indicated for 30 min followed by immunoblotting. (ii) Smad1/5 phosphorylation was analyzed in response to 20 pM Inhibin A over time, or increasing doses of Inhibin A at a fixed time point of 30 min in SKOV3 epithelial cancer cells. Lysates were immunoblotted for phospho-Smad1/5, Smad1/5 and GAPDH. HMEC-1 cells with 100pM Inhibin A treatment were tested side-by-side for comparison.
Figure S4 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
Authors: Singh Priyanka , Jenkins Laura M. , Horst Ben , Alers Victoria , Pradhan Shrikant , Kaur Prabhjot , Srivastava Tapasya , Hempel Nadine , Győrffy Balázs , Broude Eugenia V. , Lee Nam Y. , Mythreye Karthikeyan
Published: March 2023

: Growth curves of (i) HMEC-1 and MEEC cells in the presence or absence of 100pM recombinant Inhibin A over 7 days or (ii) HMEC-1 migration through fibronectin coated transwells for 6 hrs towards control serum free media or media containing 300 pM recombinant Inhibin A. Data are average of three independent biological trials. ***p<0001.(iii) Endothelial spheroids were prepared as described in Methods and plated on 24-well plates coated with growth factor reduced Matrigel and treated as indicated. Sprouts were digitally imaged after overnight treatment as indicated and the number and length of sprouts per spheroid quantitated. (iv) Growth curves of shControl and shINHA SKOV3 cells. (v) Indicated tumor cells invasion through matrigel coated transwells (vi) Sample images of nude mice injected intraperitoneally with 5x106 shControl or shINHA SKOV3 cells. Animals were sacrificed at 7 weeks and/or if body weight loss reached 20% as a humane endpoint. Ascites and metastatic burden were examined at necropsy. Dotted circles indicate the ovary. Block arrows indicate metastatic lesions.
Table S1 from Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis
Authors: Sarvi Sana , Patel Hitesh , Li Jun , Dodd Georgia L. , Creedon Helen , Muir Morwenna , Ward Jocelyn , Dawson John C. , Lee Martin , Culley Jayne , Salter Donald M. , Sims Andrew H. , Byron Adam , Brunton Valerie G.
Published: March 2023

Table S1 provides annotation of the Kindlin-1 dependent secretome
Table S4-S6 from A Large-Scale, Exome-Wide Association Study of Han Chinese Women Identifies Three Novel Loci Predisposing to Breast Cancer
Authors: Zhang Bo , Chen Men-Yun , Shen Yu-Jun , Zhuo Xian-Bo , Gao Ping , Zhou Fu-Sheng , Liang Bo , Zu Jun , Zhang Qin , Suleman Sufyan , Xu Yi-Hui , Xu Min-Gui , Xu Jin-Kai , Liu Chen-Cheng , Giannareas Nikolaos , Xia Ji-Han , Zhao Yuan , Huang Zhong-Lian , Yang Zhen , Cheng Huai-Dong , Li Na , Hong Yan-Yan , Li Wei , Zhang Min-Jun , Yu Ke-Da , Li Guoliang , Sun Meng-Hong , Chen Zhen-Dong , Wei Gong-Hong , Shao Zhi-Min
Published: March 2023

Table S4-S6 include the information of 125 previously reported SNPs, 23 reported SNPs covered by Exome_Asian Array, and genotype distribution of the three new SNPs.
Supplementary figure S1-S19 from A Large-Scale, Exome-Wide Association Study of Han Chinese Women Identifies Three Novel Loci Predisposing to Breast Cancer
Authors: Zhang Bo , Chen Men-Yun , Shen Yu-Jun , Zhuo Xian-Bo , Gao Ping , Zhou Fu-Sheng , Liang Bo , Zu Jun , Zhang Qin , Suleman Sufyan , Xu Yi-Hui , Xu Min-Gui , Xu Jin-Kai , Liu Chen-Cheng , Giannareas Nikolaos , Xia Ji-Han , Zhao Yuan , Huang Zhong-Lian , Yang Zhen , Cheng Huai-Dong , Li Na , Hong Yan-Yan , Li Wei , Zhang Min-Jun , Yu Ke-Da , Li Guoliang , Sun Meng-Hong , Chen Zhen-Dong , Wei Gong-Hong , Shao Zhi-Min
Published: March 2023

Supplementary figure S1-S19 present the results of EWAS analysis and association information of the three novel loci. The data also show the functional and clinical evidence of the three loci associated genes
Table S4 from ERα-Mediated Nuclear Sequestration of RSK2 Is Required for ER+ Breast Cancer Tumorigenesis
Authors: Ludwik Katarzyna A. , McDonald Oliver G. , Brenin David R. , Lannigan Deborah A.
Published: March 2023

Small molecule inhibitors screened for inhibition of RSK2 nuclear localization
Supplementary Tables 1-3 from STAT3/PIAS3 Levels Serve as “Early Signature” Genes in the Development of High-Grade Serous Carcinoma from the Fallopian Tube
Authors: Saini Uksha , Suarez Adrian A. , Naidu Shan , Wallbillich John J. , Bixel Kristin , Wanner Ross A. , Bice Jason , Kladney Raleigh D. , Lester Jenny , Karlan Beth Y. , Goodfellow Paul J. , Cohn David E. , Selvendiran Karuppaiyah
Published: March 2023

Role of STAT3 in high-grade serous carcinoma
Supplementary case reports from Utility of Single-Cell Genomics in Diagnostic Evaluation of Prostate Cancer
Authors: Alexander Joan , Kendall Jude , McIndoo Jean , Rodgers Linda , Aboukhalil Robert , Levy Dan , Stepansky Asya , Sun Guoli , Chobardjiev Lubomir , Riggs Michael , Cox Hilary , Hakker Inessa , Nowak Dawid G. , Laze Juliana , Llukani Elton , Srivastava Abhishek , Gruschow Siobhan , Yadav Shalini S. , Robinson Brian , Atwal Gurinder , Trotman Lloyd C. , Lepor Herbert , Hicks James , Wigler Michael , Krasnitz Alexander
Published: March 2023

A PDF file containing Supplementary case reports
Supplementary Table S4 from Utility of Single-Cell Genomics in Diagnostic Evaluation of Prostate Cancer
Authors: Alexander Joan , Kendall Jude , McIndoo Jean , Rodgers Linda , Aboukhalil Robert , Levy Dan , Stepansky Asya , Sun Guoli , Chobardjiev Lubomir , Riggs Michael , Cox Hilary , Hakker Inessa , Nowak Dawid G. , Laze Juliana , Llukani Elton , Srivastava Abhishek , Gruschow Siobhan , Yadav Shalini S. , Robinson Brian , Atwal Gurinder , Trotman Lloyd C. , Lepor Herbert , Hicks James , Wigler Michael , Krasnitz Alexander
Published: March 2023

Summary of downsampling study
Tables S1 to S3 from Nkx2-2as Suppression Contributes to the Pathogenesis of Sonic Hedgehog Medulloblastoma
Authors: Zhang Yimeng , Wang Ting , Wang Shan , Xiong Yanlu , Zhang Rui , Zhang Xiang , Zhao Jing , Yang An-Gang , Wang Lei , Jia Lintao
Published: March 2023

This file contains supplementary tables showing the nucleotide sequences for miRNAs, siRNA target sites and primers, as well as all antibodies used in the present study.
Supplementary Data from Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets
Authors: Basu Sandip K. , Lee Sook , Salotti Jacqueline , Basu Srikanta , Sakchaisri Krisada , Xiao Zhen , Walia Vijay , Westlake Christopher J. , Morrison Deborah K. , Johnson Peter F.
Published: March 2023

Supplementary Figures S1-7
Figure S8 from Type I IFN Receptor Signaling Controls IL7-Dependent Accumulation and Activity of Protumoral IL17A-Producing γδT Cells in Breast Cancer
Authors: Patin Emmanuel C. , Soulard Daphnée , Fleury Sébastien , Hassane Maya , Dombrowicz David , Faveeuw Christelle , Trottein François , Paget Christophe
Published: March 2023

Effect of IFN-beta on CD127 expression by Î³Î'T cells
Figure S6 from Type I IFN Receptor Signaling Controls IL7-Dependent Accumulation and Activity of Protumoral IL17A-Producing γδT Cells in Breast Cancer
Authors: Patin Emmanuel C. , Soulard Daphnée , Fleury Sébastien , Hassane Maya , Dombrowicz David , Faveeuw Christelle , Trottein François , Paget Christophe
Published: March 2023

IL-7 is not secreted by AT-3 breast cancer line in vitro and early IL-7 neutralization significantly reduces 4T1.2 tumor growth
Table S6C from Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses
Authors: Niklasson Mia , Maddalo Gianluca , Sramkova Zuzana , Mutlu Ercan , Wee Shimei , Sekyrova Petra , Schmidt Linnéa , Fritz Nicolas , Dehnisch Ivar , Kyriatzis Gregorios , Krafcikova Michaela , Carson Brittany B. , Feenstra Jennifer M. , Marinescu Voichita D. , Segerman Anna , Haraldsson Martin , Gustavsson Anna-Lena , Hammarström Lars G.J. , Jenmalm Jensen Annika , Uhrbom Lene , Altelaar A.F. Maarten , Linnarsson Sten , Uhlén Per , Trantirek Lukas , Vincent C. Theresa , Nelander Sven , Enger Per Øyvind , Andäng Michael
Published: March 2023

RNA sequencing data penitrem A vs control (DMSO)
Table S6A from Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses
Authors: Niklasson Mia , Maddalo Gianluca , Sramkova Zuzana , Mutlu Ercan , Wee Shimei , Sekyrova Petra , Schmidt Linnéa , Fritz Nicolas , Dehnisch Ivar , Kyriatzis Gregorios , Krafcikova Michaela , Carson Brittany B. , Feenstra Jennifer M. , Marinescu Voichita D. , Segerman Anna , Haraldsson Martin , Gustavsson Anna-Lena , Hammarström Lars G.J. , Jenmalm Jensen Annika , Uhrbom Lene , Altelaar A.F. Maarten , Linnarsson Sten , Uhlén Per , Trantirek Lukas , Vincent C. Theresa , Nelander Sven , Enger Per Øyvind , Andäng Michael
Published: March 2023

RNA sequencing data A23187 vs control (DMSO)
Table S3 from Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses
Authors: Niklasson Mia , Maddalo Gianluca , Sramkova Zuzana , Mutlu Ercan , Wee Shimei , Sekyrova Petra , Schmidt Linnéa , Fritz Nicolas , Dehnisch Ivar , Kyriatzis Gregorios , Krafcikova Michaela , Carson Brittany B. , Feenstra Jennifer M. , Marinescu Voichita D. , Segerman Anna , Haraldsson Martin , Gustavsson Anna-Lena , Hammarström Lars G.J. , Jenmalm Jensen Annika , Uhrbom Lene , Altelaar A.F. Maarten , Linnarsson Sten , Uhlén Per , Trantirek Lukas , Vincent C. Theresa , Nelander Sven , Enger Per Øyvind , Andäng Michael
Published: March 2023

Proteomics and phosphoproteomics data
Supplementary Figure S4 from Perioperative, Spatiotemporally Coordinated Activation of T and NK Cells Prevents Recurrence of Pancreatic Cancer
Authors: Brooks Jennifer , Fleischmann-Mundt Bettina , Woller Norman , Niemann Julia , Ribback Silvia , Peters Kristin , Demir Ihsan Ekin , Armbrecht Nina , Ceyhan Guralp O. , Manns Michael P. , Wirth Thomas C. , Kubicka Stefan , Bernhardt Gunter , Smyth Mark J. , Calvisi Diego F. , Gürlevik Engin , Kühnel Florian
Published: March 2023

Analysis of CD4+CD25+ cells in immune cell populations isolated from primary tumors after neoadjuvant treatment.
Supplementary Texts from Combination Therapy and the Evolution of Resistance: The Theoretical Merits of Synergism and Antagonism in Cancer
Authors: Saputra Elysia C. , Huang Lu , Chen Yihui , Tucker-Kellogg Lisa
Published: March 2023

SI Text S1. Reversibility of cellular alterations. SI Text S2. Derivation of the equation for quantifying the effect of combination therapy. SI Text S3. Alternative definitions of drug-effect parameters. SI Text S4. Approximation of TRR, the time until double resistance arises. S4.1. Derivation of the equation for the approximation of TRR S4.2. Agreement between analytical approximation and stochastic simulation S4.3. Comparisons to other models
Supplementary Table and Figures from Combination Therapy and the Evolution of Resistance: The Theoretical Merits of Synergism and Antagonism in Cancer
Authors: Saputra Elysia C. , Huang Lu , Chen Yihui , Tucker-Kellogg Lisa
Published: March 2023

SI Table S1. Treatment parameters for the antagonistic, additive, and synergistic combinations displayed in Fig. 6. SI Fig S1. The trends of TRR and Tlethal according to the Constant-Dose and the Constant-Efficacy Methods, if drug effect is exclusively anti-proliferative or exclusively pro-apoptotic. SI Fig. S2. Changes in key parameters between the Constant-Dose Method and the Constant-Efficacy Method. SI Fig. S3. The relative advantages of synergism and antagonism are consistent across simulations with random numbers of pre-existing singly-resistant cells. SI Fig. S4. A hybrid of Constant-Dose Method and Constant-Efficacy Method, analogous to Fig. 5. SI Fig. S5. The relative advantages of synergism and antagonism are consistent across a range of alteration rates, but all strategies deteriorate in the presence of fast alteration. SI Fig. S6. Giving fitness penalties to drug-resistance magnifies the relative benefits of synergism and antagonism. SI Fig. S7. Simulations of the 4-state system, if a direct leap from sensitive (SS) to doubly-resistant (RR) phenotype is permitted.
Figures S1, S2, S3, S4 from Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF
Authors: Shao Wenlin , Mishina Yuji M. , Feng Yun , Caponigro Giordano , Cooke Vesselina G. , Rivera Stacy , Wang Yingyun , Shen Fang , Korn Joshua M. , Mathews Griner Lesley A. , Nishiguchi Gisele , Rico Alice , Tellew John , Haling Jacob R. , Aversa Robert , Polyakov Valery , Zang Richard , Hekmat-Nejad Mohammad , Amiri Payman , Singh Mallika , Keen Nicholas , Dillon Michael P. , Lees Emma , Ramurthy Savithri , Sellers William R. , Stuart Darrin D.
Published: March 2023

Figure S1: pMEK and pERK suppression in KRAS mutant and BRAFV600E cells by dabrafenib or RAF709. Figure S2: pMEK and pERK suppression in NRAS mutant and BRAFV600E cells by dabrafenib or RAF709. Figure S3: Cell cycle and apoptotic effects of RAF709 in KRASmut cells. Figure S4: Antiproliferative activity of RAF709 in HPAFII cells.
Supplemental Figures from Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis
Authors: Valerio Daria G. , Xu Haiming , Chen Chun-Wei , Hoshii Takayuki , Eisold Meghan E. , Delaney Christopher , Cusan Monica , Deshpande Aniruddha J. , Huang Chun-Hao , Lujambio Amaia , Zheng YuJun George , Zuber Johannes , Pandita Tej K. , Lowe Scott W. , Armstrong Scott A.
Published: March 2023

Extra data to support the central hypothesis.
Table S2 from Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma
Authors: Reap Elizabeth A. , Suryadevara Carter M. , Batich Kristen A. , Sanchez-Perez Luis , Archer Gary E. , Schmittling Robert J. , Norberg Pamela K. , Herndon James E. , Healy Patrick , Congdon Kendra L. , Gedeon Patrick C. , Campbell Olivia C. , Swartz Adam M. , Riccione Katherine A. , Yi John S. , Hossain-Ibrahim Mohammed K. , Saraswathula Anirudh , Nair Smita K. , Dunn-Pirio Anastasie M. , Broome Taylor M. , Weinhold Kent J. , Desjardins Annick , Vlahovic Gordana , McLendon Roger E. , Friedman Allan H. , Friedman Henry S. , Bigner Darell D. , Fecci Peter E. , Mitchell Duane A. , Sampson John H.
Published: March 2023

Patient weight distribution and weight-based ATCT infusion counts.
Supplemental Figure S2: Tumors are infiltrated by more T cells in mice with Nrp1 deficient GAMs from Deletion of Neuropilin 1 from Microglia or Bone Marrow–Derived Macrophages Slows Glioma Progression
Authors: Miyauchi Jeremy Tetsuo , Caponegro Michael D. , Chen Danling , Choi Matthew K. , Li Melvin , Tsirka Stella E.
Published: March 2023

Flow cytometric analysis of purified tumor extracts from WT and KO mice, stained for CD3+CD4+ and CD3+CD8+ T cells.
Figure S3 from Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma
Authors: Reap Elizabeth A. , Suryadevara Carter M. , Batich Kristen A. , Sanchez-Perez Luis , Archer Gary E. , Schmittling Robert J. , Norberg Pamela K. , Herndon James E. , Healy Patrick , Congdon Kendra L. , Gedeon Patrick C. , Campbell Olivia C. , Swartz Adam M. , Riccione Katherine A. , Yi John S. , Hossain-Ibrahim Mohammed K. , Saraswathula Anirudh , Nair Smita K. , Dunn-Pirio Anastasie M. , Broome Taylor M. , Weinhold Kent J. , Desjardins Annick , Vlahovic Gordana , McLendon Roger E. , Friedman Allan H. , Friedman Henry S. , Bigner Darell D. , Fecci Peter E. , Mitchell Duane A. , Sampson John H.
Published: March 2023

DC vaccination enhances the proportion of CMV pp65-specific CD8+ T cells with multiple effector functions
Figure S1 from Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma
Authors: Reap Elizabeth A. , Suryadevara Carter M. , Batich Kristen A. , Sanchez-Perez Luis , Archer Gary E. , Schmittling Robert J. , Norberg Pamela K. , Herndon James E. , Healy Patrick , Congdon Kendra L. , Gedeon Patrick C. , Campbell Olivia C. , Swartz Adam M. , Riccione Katherine A. , Yi John S. , Hossain-Ibrahim Mohammed K. , Saraswathula Anirudh , Nair Smita K. , Dunn-Pirio Anastasie M. , Broome Taylor M. , Weinhold Kent J. , Desjardins Annick , Vlahovic Gordana , McLendon Roger E. , Friedman Allan H. , Friedman Henry S. , Bigner Darell D. , Fecci Peter E. , Mitchell Duane A. , Sampson John H.
Published: March 2023

Patient schematic.
Table S1 from Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation
Authors: Tommelein Joke , De Vlieghere Elly , Verset Laurine , Melsens Elodie , Leenders Justine , Descamps Benedicte , Debucquoy Annelies , Vanhove Christian , Pauwels Patrick , Gespach Christian P. , Vral Anne , De Boeck Astrid , Haustermans Karin , de Tullio Pascal , Ceelen Wim , Demetter Pieter , Boterberg Tom , Bracke Marc , De Wever Olivier
Published: March 2023

Supplementary Table S1: patient characteristics including age, sex, tumor type, and treatment
Supplementary Figure 2 from Rapid Intraoperative Diagnosis of Pediatric Brain Tumors Using Stimulated Raman Histology
Authors: Hollon Todd C. , Lewis Spencer , Pandian Balaji , Niknafs Yashar S. , Garrard Mia R. , Garton Hugh , Maher Cormac O. , McFadden Kathryn , Snuderl Matija , Lieberman Andrew P. , Muraszko Karin , Camelo-Piragua Sandra , Orringer Daniel A.
Published: March 2023

Random forest model 2. A) Example decision tree from random forest model 2. B) Out-of-bag, low-grade, and high-grade tumor classification error across 500 grown decision trees. C) Image feature importance for model 2. Similar to model 1, nuclei density and TAM density are the most important predictors; however, nuclear morphology parameters and detection of anaplasia play a more important predictive role for classifying low-grade and high-grade tumors.
Supplemental figure legends and experimental procedures from PTBP3-Mediated Regulation of ZEB1 mRNA Stability Promotes Epithelial–Mesenchymal Transition in Breast Cancer
Authors: Hou Pingfu , Li Lin , Chen Fang , Chen Yansu , Liu Hui , Li Jingjing , Bai Jin , Zheng Junnian
Published: March 2023

Supplemental figure legends and experimental procedures
Figure S3 from miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense
Authors: Pajic Marina , Froio Danielle , Daly Sheridan , Doculara Louise , Millar Ewan , Graham Peter H. , Drury Alison , Steinmann Angela , de Bock Charles E. , Boulghourjian Alice , Zaratzian Anaiis , Carroll Susan , Toohey Joanne , O’Toole Sandra A. , Harris Adrian L , Buffa Francesca M. , Gee Harriet E. , Hollway Georgina E. , Molloy Timothy J.
Published: March 2023

miR-139-5p overexpression significantly increased radiation sensitivity in 10 BC cell lines (A-I), and also sensitivity to ROS generator menadione (J).
Figure S4 from PTBP3-Mediated Regulation of ZEB1 mRNA Stability Promotes Epithelial–Mesenchymal Transition in Breast Cancer
Authors: Hou Pingfu , Li Lin , Chen Fang , Chen Yansu , Liu Hui , Li Jingjing , Bai Jin , Zheng Junnian
Published: March 2023

Figure S4 shows the cellular location of PTBP3 in breast cancer cells
Supplementary legends from Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma
Authors: Makinoshima Hideki , Umemura Shigeki , Suzuki Ayako , Nakanishi Hiroki , Maruyama Ami , Udagawa Hibiki , Mimaki Sachiyo , Matsumoto Shingo , Niho Seiji , Ishii Genichiro , Tsuboi Masahiro , Ochiai Atsushi , Esumi Hiroyasu , Sasaki Takehiko , Goto Koichi , Tsuchihara Katsuya
Published: March 2023

Supplementary figure legends
Supplementary Tables from Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma
Authors: Makinoshima Hideki , Umemura Shigeki , Suzuki Ayako , Nakanishi Hiroki , Maruyama Ami , Udagawa Hibiki , Mimaki Sachiyo , Matsumoto Shingo , Niho Seiji , Ishii Genichiro , Tsuboi Masahiro , Ochiai Atsushi , Esumi Hiroyasu , Sasaki Takehiko , Goto Koichi , Tsuchihara Katsuya
Published: March 2023

Supplementary Table S1. The pathway classification of metabolites used for the MSEA Supplementary Table S2. Genetic profiles in 42 SCLC cell lines Supplementary Table S3. Quantitative phospho-peptide analysis in H1048 cells with or without Gedatolisib treatment Supplementary Table S4. Quantitative phosphatidyl lipids analysis in SCLC cell Supplementary Table S5. Quantitative phosphatidyl lipids analysis in H1048 cells Supplementary Table S6. 116 metabolites in SCLC cells with or without Gedatolisib treatment Supplementary Table S7. 116 metabolites in H1048 and SBC5 with or without Gedatolisib treatment Supplementary Table S8. Metabolite set enrichment analysis (MSEA) to identify significantly enriched metabolic pathways related to gedatolisib Supplementary Table S9. Amount of 116 metabolites in SCLC tissues
Table S2 from Genetic Hitchhiking and Population Bottlenecks Contribute to Prostate Cancer Disparities in Men of African Descent
Authors: Lachance Joseph , Berens Ali J. , Hansen Matthew E.B. , Teng Andrew K. , Tishkoff Sarah A. , Rebbeck Timothy R.
Published: March 2023

Risk allele frequencies of 68 CaP SNPS in 64 global populations.
Table S1 from Genetic Hitchhiking and Population Bottlenecks Contribute to Prostate Cancer Disparities in Men of African Descent
Authors: Lachance Joseph , Berens Ali J. , Hansen Matthew E.B. , Teng Andrew K. , Tishkoff Sarah A. , Rebbeck Timothy R.
Published: March 2023

List of 64 study populations, including geographic location and sample size.
Supplementary Material and Methods from Lapatinib Resistance in Breast Cancer Cells Is Accompanied by Phosphorylation-Mediated Reprogramming of Glycolysis
Authors: Ruprecht Benjamin , Zaal Esther A. , Zecha Jana , Wu Wei , Berkers Celia R. , Kuster Bernhard , Lemeer Simone
Published: March 2023

Supplementary Material and Methods
Supplementary Figures including Figure legends from Lapatinib Resistance in Breast Cancer Cells Is Accompanied by Phosphorylation-Mediated Reprogramming of Glycolysis
Authors: Ruprecht Benjamin , Zaal Esther A. , Zecha Jana , Wu Wei , Berkers Celia R. , Kuster Bernhard , Lemeer Simone
Published: March 2023

Figure S1. Quality of phospho(proteomic) dataset acquired. Figure S2. (Phospho)proteomic analysis of lapatinib mode of action in parental cells. Figure S3. Signaling reprogramming in lapatinib resistance. Figure S4. Identification of pharmacologically actionable targets and phenotypes based on a breast cancer model of lapatinib resistance. Figure S5. Metabolic changes in lapatinib resistant cell line model.
Supplemental Figures 1 to 4 from MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels
Authors: Lu Yunqi , Hu Zhongyi , Mangala Lingegowda S. , Stine Zachary E. , Hu Xiaowen , Jiang Dahai , Xiang Yan , Zhang Youyou , Pradeep Sunila , Rodriguez-Aguayo Cristian , Lopez-Berestein Gabriel , DeMarzo Angelo M. , Sood Anil K. , Zhang Lin , Dang Chi V.
Published: March 2023

Figure S1. The expression of DANCR is upregulated by MYC activation in P493-6 cells Normalized expression of DANCR (KIAA0114) in MYC-OFF or MYC-ON P493-6 cells measured by exon microarrays (PLoS One 6, e26057). Three independent array experiments were performed. Figure S2. Human-mouse sequence alignment analysis of DANCR and mDancr Figure S3. The mRNA expression of the DANCR adjacent protein-coding genes in cells transduced with DANCR-specific siRNA Control and DANCR siRNAs were transduced into PC3 cells. After 48 and 72 hours, the mRNA expression levels of the DANCR adjacent protein-coding genes (ERVMER34-1 and UPS46) were analyzed by qRT-PCR. Figure S4. Effects of two DANCR targeting antisense morpholinos on P493-6 cell proliferation and p21 expression. A. RT-PCR analysis of DANCR expression in P493-6 after being treated by various concentrations of the two DANCR antisense morpholinos. B. Effects of two different morpholinos targeting DANCR on proliferation of P493-6 cells as compared with control morpholino. C. Induction of P21 by loss of DANCR expression in P493-6 cells treated by two concentrations of the two DANCR antisense morpholinos.
Filtered and normalized proteome dataset from Lapatinib Resistance in Breast Cancer Cells Is Accompanied by Phosphorylation-Mediated Reprogramming of Glycolysis
Authors: Ruprecht Benjamin , Zaal Esther A. , Zecha Jana , Wu Wei , Berkers Celia R. , Kuster Bernhard , Lemeer Simone
Published: March 2023

Phosphorylation site abundance dataset containing filtered, processed and annotated phosphorylation sites; STRING phosphoprotein input and output data for the lapatinib mode of action network and two dimensional enrichment analysis comparing lapatinib treatment of parental cells to phosphorylation changes in resistance (only significant terms).
Filtered and normalized phosphoproteome dataset from Lapatinib Resistance in Breast Cancer Cells Is Accompanied by Phosphorylation-Mediated Reprogramming of Glycolysis
Authors: Ruprecht Benjamin , Zaal Esther A. , Zecha Jana , Wu Wei , Berkers Celia R. , Kuster Bernhard , Lemeer Simone
Published: March 2023

Phosphorylation site abundance dataset containing filtered, processed and annotated phosphorylation sites; STRING phosphoprotein input and output data for the lapatinib mode of action network and two dimensional enrichment analysis comparing lapatinib treatment of parental cells to phosphorylation changes in resistance (only significant terms).
Supplementary Figure S5 from CD163 Is Required for Protumoral Activation of Macrophages in Human and Murine Sarcoma
Authors: Shiraishi Daisuke , Fujiwara Yukio , Horlad Hasita , Saito Yoichi , Iriki Toyohisa , Tsuboki Junko , Cheng Pan , Nakagata Naomi , Mizuta Hiroshi , Bekki Hirofumi , Nakashima Yasuharu , Oda Yoshinao , Takeya Motohiro , Komohara Yoshihiro
Published: March 2023

Immune cell infiltration in tumor tissues. The percentage of CD11b+Gr-1+ myeloid derived suppressor cells (MDSCs), EMR1+ TAMs, and CD3+ T cells in MCA205 tumor nodules were evaluated by flow cytometry.
Figure S1 from Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells
Authors: Walser Tonya C. , Jing Zhe , Tran Linh M. , Lin Ying Q. , Yakobian Natalie , Wang Gerald , Krysan Kostyantyn , Zhu Li X. , Sharma Sherven , Lee Mi-Heon , Belperio John A. , Ooi Aik T. , Gomperts Brigitte N. , Shay Jerry W. , Larsen Jill E. , Minna John D. , Hong Long-sheng , Fishbein Michael C. , Dubinett Steven M.
Published: March 2023

Figure S1 provides additional evidence that Snail is expressed during pulmonary premalignancy.
Figure S5 from Photodynamic Priming Mitigates Chemotherapeutic Selection Pressures and Improves Drug Delivery
Authors: Huang Huang-Chiao , Rizvi Imran , Liu Joyce , Anbil Sriram , Kalra Ashish , Lee Helen , Baglo Yan , Paz Nancy , Hayden Douglas , Pereira Steve , Pogue Brian W. , Fitzgerald Jonathan , Hasan Tayyaba
Published: March 2023

Endpoint primary metastatic burdens were comparable mice treated with 'nal-IR' and 'PDT + nal-IRI'.
Supplementary Figure Legends from NKG2D-Based CAR T Cells and Radiotherapy Exert Synergistic Efficacy in Glioblastoma
Authors: Weiss Tobias , Weller Michael , Guckenberger Matthias , Sentman Charles L. , Roth Patrick
Published: March 2023

revised supplementary figure legends in clean version
Supplemetal data from Genetic Ablation of Rbm38 Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating PTEN
Authors: Zhang Jin , Xu Enshun , Ren Cong , Yang Hee Jung , Zhang Yanhong , Sun Wenqiang , Kong Xiangmudong , Zhang Weici , Chen Mingyi , Huang Eric , Chen Xinbin
Published: March 2023

Supplemental Fig. S1 represents analysis of TLBL. Supplemental Fig. S2 contains representative images of H.E.-stained tumors. Supplemental Fig. S3 contains RT-PCR analysis of various genes (Tbet, NFAT1,NFAT2, IFNG, IL6) in thymus and TLBLs. Supplemental table S1-4 contains gender, survival, and tumor information of the mice.
Table S5 from microRNA-1246 Is an Exosomal Biomarker for Aggressive Prostate Cancer
Authors: Bhagirath Divya , Yang Thao Ly , Bucay Nathan , Sekhon Kirandeep , Majid Shahana , Shahryari Varahram , Dahiya Rajvir , Tanaka Yuichiro , Saini Sharanjot
Published: March 2023

List of primers used for cloning of luciferase reporter constructs
Supplementary Methods and Data from TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer
Authors: Byrd Tiara T. , Fousek Kristen , Pignata Antonella , Szot Christopher , Samaha Heba , Seaman Steven , Dobrolecki Lacey , Salsman Vita S. , Oo Htoo Zarni , Bielamowicz Kevin , Landi Daniel , Rainusso Nino , Hicks John , Powell Suzanne , Baker Matthew L. , Wels Winfried S. , Koch Joachim , Sorensen Poul H. , Deneen Benjamin , Ellis Matthew J. , Lewis Michael T. , Hegde Meenakshi , Fletcher Bradley S. , St. Croix Brad , Ahmed Nabil
Published: March 2023

Information about methods and data that further support the claims made in this article. This includes, but is not limited to TEM8 distribution in normal tissues, CAR T cell normalization, additional control groups and CAR toxicity studies.
Supplementary Table S4 from ER Stress Signaling Promotes the Survival of Cancer “Persister Cells” Tolerant to EGFR Tyrosine Kinase Inhibitors
Authors: Terai Hideki , Kitajima Shunsuke , Potter Danielle S. , Matsui Yusuke , Quiceno Laura Gutierrez , Chen Ting , Kim Tae-jung , Rusan Maria , Thai Tran C. , Piccioni Federica , Donovan Katherine A. , Kwiatkowski Nicholas , Hinohara Kunihiko , Wei Guo , Gray Nathanael S. , Fischer Eric S. , Wong Kwok-Kin , Shimamura Teppei , Letai Anthony , Hammerman Peter S. , Barbie David A.
Published: March 2023

Gene list for customized mini-screen
Figure S5 from TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer
Authors: Byrd Tiara T. , Fousek Kristen , Pignata Antonella , Szot Christopher , Samaha Heba , Seaman Steven , Dobrolecki Lacey , Salsman Vita S. , Oo Htoo Zarni , Bielamowicz Kevin , Landi Daniel , Rainusso Nino , Hicks John , Powell Suzanne , Baker Matthew L. , Wels Winfried S. , Koch Joachim , Sorensen Poul H. , Deneen Benjamin , Ellis Matthew J. , Lewis Michael T. , Hegde Meenakshi , Fletcher Bradley S. , St. Croix Brad , Ahmed Nabil
Published: March 2023

No overt toxicity detected in mice receiving TEM8 CAR T cells.
Supplementary Table S3 from ER Stress Signaling Promotes the Survival of Cancer “Persister Cells” Tolerant to EGFR Tyrosine Kinase Inhibitors
Authors: Terai Hideki , Kitajima Shunsuke , Potter Danielle S. , Matsui Yusuke , Quiceno Laura Gutierrez , Chen Ting , Kim Tae-jung , Rusan Maria , Thai Tran C. , Piccioni Federica , Donovan Katherine A. , Kwiatkowski Nicholas , Hinohara Kunihiko , Wei Guo , Gray Nathanael S. , Fischer Eric S. , Wong Kwok-Kin , Shimamura Teppei , Letai Anthony , Hammerman Peter S. , Barbie David A.
Published: March 2023

Ranked gene list by STARS algorithm
Figure S2 from TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer
Authors: Byrd Tiara T. , Fousek Kristen , Pignata Antonella , Szot Christopher , Samaha Heba , Seaman Steven , Dobrolecki Lacey , Salsman Vita S. , Oo Htoo Zarni , Bielamowicz Kevin , Landi Daniel , Rainusso Nino , Hicks John , Powell Suzanne , Baker Matthew L. , Wels Winfried S. , Koch Joachim , Sorensen Poul H. , Deneen Benjamin , Ellis Matthew J. , Lewis Michael T. , Hegde Meenakshi , Fletcher Bradley S. , St. Croix Brad , Ahmed Nabil
Published: March 2023

L2 CAR T cells reduce mammosphere formation when compared to irrelevant CAR control cells.
Figure S1 from TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer
Authors: Byrd Tiara T. , Fousek Kristen , Pignata Antonella , Szot Christopher , Samaha Heba , Seaman Steven , Dobrolecki Lacey , Salsman Vita S. , Oo Htoo Zarni , Bielamowicz Kevin , Landi Daniel , Rainusso Nino , Hicks John , Powell Suzanne , Baker Matthew L. , Wels Winfried S. , Koch Joachim , Sorensen Poul H. , Deneen Benjamin , Ellis Matthew J. , Lewis Michael T. , Hegde Meenakshi , Fletcher Bradley S. , St. Croix Brad , Ahmed Nabil
Published: March 2023

TEM8 distribution in normal tissues
Figure S6 from IRAK1 Augments Cancer Stemness and Drug Resistance via the AP-1/AKR1B10 Signaling Cascade in Hepatocellular Carcinoma
Authors: Cheng Bowie Y. , Lau Eunice Y. , Leung Hoi-Wing , Leung Carmen Oi-Ning , Ho Nicole P. , Gurung Shilpa , Cheng Lily K. , Lin Chi Ho , Lo Regina Cheuk-Lam , Ma Stephanie , Ng Irene Oi-Lin , Lee Terence K.
Published: March 2023

Knockdown of AKR1B10 suppressed liver T-IC properties including sphere formation, sorafenib resistance and expression of T-IC markers
Supplemental Fig 5 from Aberrant Phosphorylation of SMAD4 Thr277-Mediated USP9x–SMAD4 Interaction by Free Fatty Acids Promotes Breast Cancer Metastasis
Authors: Wu Yong , Yu Xiaoting , Yi Xianghua , Wu Ke , Dwabe Sami , Atefi Mohammad , Elshimali Yahya , Kemp Kevin T. , Bhat Kruttika , Haro Jesse , Sarkissyan Marianna , Vadgama Jaydutt V.
Published: March 2023

Figure S5 USP9x is responsible for TGF-beta-induced SMAD4 deubiquitination, Related to Figure 5. MDA-MB-231 cells were transfected with WT-SMAD4, HA-ubiquitin, and the indicated shRNAs and incubated with BSA or PA in the presence or absence of 3 ng/ml TGF-beta1 for 2 h. The effective knockdown of USP9x was confirmed by Western blot analysis before ubiquitination assays. Nuclear SMAD4 monoubiquitination (Mono-Ub) was detected by anti-SMAD4 immunoprecipitation and immunoblot with HA-ubiquitin. The blot is a representative of 3 blots from 3 independent experiments. *P<0.05 vs Control (shControl/-TGF-beta/-PA); #P<0.01 vs shControl/-PA; $P<0.05 shControl/+PA.
Figure S4 from IRAK1 Augments Cancer Stemness and Drug Resistance via the AP-1/AKR1B10 Signaling Cascade in Hepatocellular Carcinoma
Authors: Cheng Bowie Y. , Lau Eunice Y. , Leung Hoi-Wing , Leung Carmen Oi-Ning , Ho Nicole P. , Gurung Shilpa , Cheng Lily K. , Lin Chi Ho , Lo Regina Cheuk-Lam , Ma Stephanie , Ng Irene Oi-Lin , Lee Terence K.
Published: March 2023

IRAK1/4-Inh at low dose shows suppressive effect on sphere formation and sensitization to sorafenib and doxorubucin
Figure S2 from IRAK1 Augments Cancer Stemness and Drug Resistance via the AP-1/AKR1B10 Signaling Cascade in Hepatocellular Carcinoma
Authors: Cheng Bowie Y. , Lau Eunice Y. , Leung Hoi-Wing , Leung Carmen Oi-Ning , Ho Nicole P. , Gurung Shilpa , Cheng Lily K. , Lin Chi Ho , Lo Regina Cheuk-Lam , Ma Stephanie , Ng Irene Oi-Lin , Lee Terence K.
Published: March 2023

qPCR and western blot analyses show no correlation between mRNA and protein levels of IRAK4
Supplementary Figure S1, S2, S3, S4, S5, S6, S7, S8, S9 from Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3
Authors: Delwar Zahid M. , Kuo Yvonne , Wen Yan H. , Rennie Paul S. , Jia William
Published: March 2023

Supplementary method and supplementary figures
Supplemental figures from Loss of NDRG2 Expression Confers Oral Squamous Cell Carcinoma with Enhanced Metastatic Potential
Authors: Tamura Tomohiro , Ichikawa Tomonaga , Nakahata Shingo , Kondo Yudai , Tagawa Yuri , Yamamoto Koji , Nagai Kentaro , Baba Takashi , Yamaguchi Ryoji , Futakuchi Mitsuru , Yamashita Yoshihiro , Morishita Kazuhiro
Published: March 2023

Supplemental Figure 1. Keratin staining of cervical lymph nodes from Ndrg2-deficient mice treated with 4-NQO. Supplementary figure related to Figure 2; Supplemental Figure 2. Effect of 4-NQO treatment on an OSCC cell line was observed through the activation of the AKT signalling pathway and cell migration ability. Supplementary figure related to Figure 4; Supplemental Figure 3. Immunofluorescence staining of E-cadherin, Vimentin, and NDRG2 in OSCC cell lines for determining EMT progression by treatment with 4-NQO. Supplementary figure related to Figure 5; Supplemental Figure 4. Activation of NF-kappaB signalling in SAS/OSCC cell line treated with 4-NQO. Supplementary figure related to Figure 6; Supplemental Figure 5. Hypothetical model for the molecular mechanism of EMT progression in OSCC cells. Supplementary figure related to Figure 6 and Discussion.
Supplementary Table 3 from Cyp24a1 Attenuation Limits Progression of BrafV600E-Induced Papillary Thyroid Cancer Cells and Sensitizes Them to BRAFV600E Inhibitor PLX4720
Authors: Zou Minjing , Baitei Essa Y. , BinEssa Huda A. , Al-Mohanna Futwan A. , Parhar Ranjit S. , St-Arnaud René , Kimura Shioko , Pritchard Catrin , Alzahrani Ali S. , Assiri Abdullah M. , Meyer Brian F. , Shi Yufei
Published: March 2023

Supplementary Table 3. Top 100 differentially expressed genes in BVECyp24a1-null cells
File S1 from Bivalent Chromatin Domains in Glioblastoma Reveal a Subtype-Specific Signature of Glioma Stem Cells
Authors: Hall Amelia Weber , Battenhouse Anna M. , Shivram Haridha , Morris Adam R. , Cowperthwaite Matthew C. , Shpak Max , Iyer Vishwanath R.
Published: March 2023

sequencing statistics for all datasets in this study.
Figure S2 from Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression
Authors: Kumar Dhruv , New Jacob , Vishwakarma Vikalp , Joshi Radhika , Enders Jonathan , Lin Fangchen , Dasari Sumana , Gutierrez Wade R. , Leef George , Ponnurangam Sivapriya , Chavan Hemantkumar , Ganaden Lydia , Thornton Mackenzie M. , Dai Hongying , Tawfik Ossama , Straub Jeffrey , Shnayder Yelizaveta , Kakarala Kiran , Tsue Terance Ted , Girod Douglas A. , Van Houten Bennett , Anant Shrikant , Krishnamurthy Partha , Thomas Sufi Mary
Published: March 2023

CAF secreted HGF mediates HNSCC glycolysis.
Supplementary Figures and Tables from Forkhead Box F2 Suppresses Gastric Cancer through a Novel FOXF2–IRF2BPL–β-Catenin Signaling Axis
Authors: Higashimori Akira , Dong Yujuan , Zhang Yanquan , Kang Wei , Nakatsu Geicho , Ng Simon S.M. , Arakawa Tetsuo , Sung Joseph J.Y. , Chan Francis K.L. , Yu Jun
Published: March 2023

Forkhead box F2 suppresses gastric cancer through a novel FOXF2-IRF2BPL-β-catenin signaling axis
Sup Fig 6 from New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging
Authors: Brighton Hailey E. , Angus Steven P. , Bo Tao , Roques Jose , Tagliatela Alicia C. , Darr David B. , Karagoz Kubra , Sciaky Noah , Gatza Michael L. , Sharpless Norman E. , Johnson Gary L. , Bear James E.
Published: March 2023

mRNAseq pathway signature analysis reveals gene expression reprogramming on MEKi.
Supplementary Figure 4 from Atypical G Protein β5 Promotes Cardiac Oxidative Stress, Apoptosis, and Fibrotic Remodeling in Response to Multiple Cancer Chemotherapeutics
Authors: Chakraborti Sreemoyee , Pramanick Arnab , Saha Sudipta , Roy Somnath Singha , Chaudhuri Arnab Ray , Das Madhusudan , Ghosh Sujoy , Stewart Adele , Maity Biswanath
Published: March 2023

Figure S4. Gβ5 knockdown obviates mobilization of antioxidant defense systems in VCM exposed to chemotherapeutic drugs.
Sup Fig 1 from New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging
Authors: Brighton Hailey E. , Angus Steven P. , Bo Tao , Roques Jose , Tagliatela Alicia C. , Darr David B. , Karagoz Kubra , Sciaky Noah , Gatza Michael L. , Sharpless Norman E. , Johnson Gary L. , Bear James E.
Published: March 2023

Achievement of reproducible spatial and temporal control of melanoma growth with <400 initiating cells
Supplementary Figure 2 from Atypical G Protein β5 Promotes Cardiac Oxidative Stress, Apoptosis, and Fibrotic Remodeling in Response to Multiple Cancer Chemotherapeutics
Authors: Chakraborti Sreemoyee , Pramanick Arnab , Saha Sudipta , Roy Somnath Singha , Chaudhuri Arnab Ray , Das Madhusudan , Ghosh Sujoy , Stewart Adele , Maity Biswanath
Published: March 2023

Figure S2. Validation of Gβ5-targeted shRNA constructs.
Figure S4 from Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints
Authors: Gourdin Nicolas , Bossennec Marion , Rodriguez Céline , Vigano Selena , Machon Christelle , Jandus Camilla , Bauché David , Faget Julien , Durand Isabelle , Chopin Nicolas , Tredan Olivier , Marie Julien C. , Dubois Bertrand , Guitton Jérôme , Romero Pedro , Caux Christophe , Ménétrier-Caux Christine
Published: March 2023

Impact of CD39 or CD73 inhibitor (ARL67156, APCP) on ATP-mediated inhibition of CD73+ or CD73neg CD4+ Teff in the presence of Treg based on the proliferation markers profiles (Cell trace Violet or CFSE)
Supplementary Materials and Methods from Fibrinolytic Enzyme Cotherapy Improves Tumor Perfusion and Therapeutic Efficacy of Anticancer Nanomedicine
Authors: Kirtane Ameya R. , Sadhukha Tanmoy , Kim Hyunjoon , Khanna Vidhi , Koniar Brenda , Panyam Jayanth
Published: March 2023

Description of additional methods and procedures used in the study.
Figure S5 from The E3 Ligase RING1 Targets p53 for Degradation and Promotes Cancer Cell Proliferation and Survival
Authors: Shen Jiajia , Li Pengyu , Shao Xuejing , Yang Yang , Liu Xiujun , Feng Min , Yu Qiang , Hu Ronggui , Wang Zhen
Published: March 2023

Knockdown of RING1 suppresses cancer cell migration and inhibits tumor growth in vivo
Supplementary Figure S6 from Fibrinolytic Enzyme Cotherapy Improves Tumor Perfusion and Therapeutic Efficacy of Anticancer Nanomedicine
Authors: Kirtane Ameya R. , Sadhukha Tanmoy , Kim Hyunjoon , Khanna Vidhi , Koniar Brenda , Panyam Jayanth
Published: March 2023

Intra-organ and intratumoral distribution of Doxil with and without tPA.
Supplementary Figure S1 from Fibrinolytic Enzyme Cotherapy Improves Tumor Perfusion and Therapeutic Efficacy of Anticancer Nanomedicine
Authors: Kirtane Ameya R. , Sadhukha Tanmoy , Kim Hyunjoon , Khanna Vidhi , Koniar Brenda , Panyam Jayanth
Published: March 2023

Fibrin(ogen) staining in human lung carcinomas.
Figure S4. from PADI2-Mediated Citrullination Promotes Prostate Cancer Progression
Authors: Wang Lin , Song Guanhua , Zhang Xiang , Feng Tingting , Pan Jihong , Chen Weiwen , Yang Muyi , Bai Xinnuo , Pang Yu , Yu Jindan , Han Jinxiang , Han Bo
Published: March 2023

Effects of truncate PADI2 on AR activity. Various truncated PADI2 were constructed and their cytoplasmic/nuclear locations differ. PADI2 in its different lengthen could activate AR signaling through citrullination.
Figure S1. from PADI2-Mediated Citrullination Promotes Prostate Cancer Progression
Authors: Wang Lin , Song Guanhua , Zhang Xiang , Feng Tingting , Pan Jihong , Chen Weiwen , Yang Muyi , Bai Xinnuo , Pang Yu , Yu Jindan , Han Jinxiang , Han Bo
Published: March 2023

Characterization of PADI2 and PADI4 in PCa cells with the stimulation of androgen and the effect of siPADI4 on cell viability of PCa cells. Androgen suppresses the expression of PADI2, but not PADI4 in PCa cells and silencing PADI4 makes no obvious effect on cell viability of PCa cells.
Supplementary Information from A p53-Responsive miRNA Network Promotes Cancer Cell Quiescence
Authors: La Ting , Liu Guang Zhi , Farrelly Margaret , Cole Nicole , Feng Yu Chen , Zhang Yuan Yuan , Sherwin Simonne K. , Yari Hamed , Tabatabaee Hessam , Yan Xu Guang , Guo Su Tang , Liu Tao , Thorne Rick F. , Jin Lei , Zhang Xu Dong
Published: March 2023

Supplementary Table 1. A summary of miRNAs that are expressed at higher levels in G0 cells than G1 cells. Supplementary Table 2. List of antibodies. Supplementary Table 3. List of Reagents. Supplementary Table 4. siRNA and shRNA sequences. Supplementary Table 5. Lists of plasmids obtained commercially. Supplementary Table 6. Lists of plasmids constructed in house. Supplementary Table 7. List of primers for qPCR, ChIP and plasmids construction.