bluuebunny/crossref_metadata_2025 huggingface dataset:
Successful Identification of Key Phytoconstituents of Emblica officinalis as Potential Multitargeting Anti-Inflammatory and Antifungal Agents
Authors: Choudhary Diksha , Rani Nidhi , Kaur Rajwinder
Published: August 2024

Introduction:

Fungal infections are growing more rapidly and becoming a public
health concern worldwide. The use of herbal medicines is now increasing due to their many
functional properties with fewer side effects. Emblica officinalis, an important medicinal plant,
exhibits many therapeutic properties.

Methods:

In this article, the active phytoconstituents of Emblica officinalis were explored for
their multitargeting activity as anti-inflammatory and antifungal by computational analysis.

Results:

A total of nine phytoconstituents including 3,6-di-O-galloyl-D-glucose, Mucic acid-
1,4-lactone-2-O-gallate, Mucic acid-1,4-lactone-5-O-gallate, Mucic acid-1,4-lactone-3-O-gallate,
Mucic acid-1,4-lactone-3,5-di-O-gallate, 2,6-dimethoxy-4-(2-hydroxyethyl)phenol-1-Obeta-
D-glucopyranoside, Apigenin-7-O-(6'-butyryl-beta-glucopyranoside), S-eriodictoyl-7-O-
(6'-O-trans-p-coumaryl)-beta-D-glucopyranoside, and 1,2,3,4,6-penta-O-galloyl glucose
showed better results as compared to standard drugs taken in the study.

Conclusion:

Further, these constituents indicated good ADME properties during the SwissADME
online analysis.
Management of Rheumatoid Arthritis By Development of Nanocarriers
and their Significance Over Conventional Dosage Forms
Authors: khan Hafsa , Yadav Nita , Sharma Shipra , Rawat Reetika
Published: August 2024

Background:

Rheumatoid Arthritis is one of the most common auto-immune diseases
that cause inflammation. It is characterized by pain, stiffness, tenderness, and swelling in joints,
which may even lead to heart, lungs, or brain-related problems where age is the major factor involved,
as around 55% older adults have been affected by it. Treatments including non-steroidal anti-
inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs) etc., that are
modified and formulated as nanocarriers for enhanced bioavailability, majorly aim at enhancing the
rate and extent of drug reaching the bloodstream such as solid-lipid nanoparticles, liposomes, polymeric-
micelles, polymeric nanoparticles etc. are used in the management of rheumatoid arthritis.

Methods:

The following tools (Pubmed, Scopus, Google search engine, Google Scholar, Medline
Search Engine, Elsevier) were used in the literature search.

Results:

Through the literature review, the development of nanocarrier shows a promising approach
in the management of rheumatoid arthritis as compared to the conventional drug treatment such as
biologic agents and non-steroidal anti-inflammatory drugs etc.

Conclusion:

Rheumatoid Arthritis is a condition that occurs when the immune system, which normally
helps to protect the body from infection and disease, attacks its own tissues. The disease
causes pain, swelling as well as loss of function in joints. Therefore, life-long management is required
by reducing the dose frequency and dosage regimen, which can be effectively approached by
the development of a nano-carrier for significant drug uptake and low toxicity.
MiRNA Dysregulation in Brain Injury: An In Silico Study to Clarify the
Role of a MiRNA Set
Authors: Sessa Francesco , Pomara Cristoforo , Schembari Flavia , Esposito Massimiliano , Capasso Emanuele , Pesaresi Mauro , Osuna Eduardo , Ulas Efehan , Zammit Christian , Salerno Monica
Published: August 2024

Background:

The identification of specific circulating miRNAs has been proposed as a
valuable tool for elucidating the pathophysiology of brain damage or injury and predicting patient outcomes.

Objective:

This study aims to apply several bioinformatic tools in order to clarify miRNA interactions
with potential genes involved in brain injury, emphasizing the need of using a computational approach
to determine the most likely correlations between miRNAs and target genes. Specifically, this study
centers on elucidating the roles of miR-34b, miR-34c, miR-135a, miR-200c, and miR-451a.

Methods:

After a careful evaluation of different software available (analyzing the strengths and limitations),
we applied three tools, one to perform an analysis of the validated targets (miRTarBase), and
two to evaluate functional annotations (miRBase and TAM 2.0).

Results:

Research findings indicate elevated levels of miR-135a and miR-34b in patients with traumatic
brain injury (TBI) within the first day post-injury, while miR-200c and miR-34c were found to
be upregulated after 7 days. Moreover, miR-451a and miR-135a were found overexpressed in the serum,
while miRNAs 34b, 34c, and 200c, had lower serum levels at baseline post brain injury.

Conclusion:

This study emphasizes the use of computational methods in determining the most likely
relationships between miRNAs and target genes by investigating several bioinformatic techniques to
elucidate miRNA interactions with potential genes. Specifically, this study focuses on the functions of
miR-34b, miR-34c, miR-135a, miR-200c, and miR-451a, providing an up-to-date overview and suggesting
future research directions for identifying theranomiRNAs related to brain injury, both at the
tissue and serum levels.
Exploring the use of translanguaging in the EFL Classroom: Students’ feelings and attitudes on the role of first language and English-only instruction
Authors: Bouguerra Mohamed Amine
Published: August 2024

This study investigates the perspectives and attitudes of students in an English as a Foreign Language (EFL) classroom towards the use of their first language (L1) and English-only instruction. The aim is to understand how students perceive translanguaging and the role of their first language in the classroom and whether they believe incorporating it alongside English (L2) enhances their ability to express themselves and understand the content. This research took place in an adult high school in Indianapolis, IN USA. The findings reveal that students generally value the opportunity to use their first language in the classroom, as it helps them feel more comfortable, secure, and able to ask questions and seek clarification. However, there is also a preference among some students for English-only instruction, as they believe it facilitates language learning and immersion. These results suggest that incorporating students' first language in the EFL classroom may have pedagogical benefits, particularly in terms of improving students' confidence and understanding. The findings also highlight the importance of striking a balance between English-only instruction and incorporating students' first language to create an inclusive and supportive learning environment.
PENGARUH REVITALISASI TERHADAP PENURUNAN TINGKAT KEKUMUHAN DI KAMPUNG MELAYU, KOTA SEMARANG
Authors: Flandi Tito Pratama  , Mussadun
Published: August 2024

Kampung Melayu merupakan satu dari empat kampung bersejarah yang ada di Kota Semarang, namun kondisinya saat ini sedang mengalami degradasi dari berbagai aspek yang menyebabkan kawasan ini menjadi marginal, kumuh, tidak produktif, serta menjadi beban bagi Pemerintah Kota Semarang. Oleh sebab itu pada tahun 2021 Pemerintah Kota Semarang melakukan kegiatan revitalisasi yang bertujuan untuk menangani permasalahan kekumuhan yang ada di Kampung Melayu. Sehingga tujuan dari penelitian ini adalah untuk mengetahui pengaruh kegiatan revitalisasi terhadap kondisi tingkat kekumuhan yang ada di Kampung Melayu. Sasaran penelitian ini meliputi identifikasi tahapan revitalisasi dan analisis tingkat kekumuhan di Kampung Melayu baik sebelum dan sesudah revitalisasi. Metode analisis yang digunakan adalah metode kuantitatif dengan teknik analisisnya yakni analisis statistik deskriptif dan analisis skoring. Hasil dari penelitian ini diketahui bahwa kegiatan revitalisasi berpengaruh terhadap penurunan tingkat kekumuhan yang ditunjukkan pada variabel-variabel yang meliputi Kondisi Jalan Lingkungan, Kondisi Drainsae Lingkungan, dan Kondisi Pengelolaan Persampahan. Sedangkan kegiatan Revitalisasi ternyata tidak atau kurang berpengaruh terhadap penurunan tingkat kekumuhan yang ditunjukkan pada variabel-variabel yang meliputi Kondisi Bangunan Gedung, Kondisi Penyediaan Minum, Kondisi Pengelolaan Air Limbah, dan Kondisi Pengaman Kebakaran.
Catarsis: una purificación emocional desde la experiencia artística
Authors: Vargas Rodríguez Félix Alberto
Published: August 2024

Concebida por el grupo de danza Patojos Getdown de la ciudad de Popayán, Colombia, Catarsis es una puesta en obra dancística que integra diversos estilos de danza moderna y danzas urbanas con el teatro y la voz humana, configurando una forma expresiva conocida como danza teatro. Partiendo de la experiencia colectiva y las vivencias personales de los protagonistas en el entorno de su ciudad, y sustentada en referentes filosóficos como la categoría estética catarsis, formulada por el filósofo griego Aristóteles, y psicológicos como la teoría del inconsciente colectivo, propuesta por el médico psiquiatra Carl G. Jung, la obra propone, en el transcurso de nueve escenas, una reflexión sobre algunos rituales sociales propios de muchas ciudades colombianas, en los que se arraigan estructuras paternalistas con sus secuelas de intolerancia y exclusión del otro diferente. También plantea la posibilidad de resiliencia y emancipación por medio de la experiencia artística.
Healthy snack quartet education on knowledge and sodium intake in overweight early adolescents
Authors: Sapang Ferliani Fransisca , Andayani Tri Rejeki , Muthmainah Muthmainah
Published: August 2024

Background: Child and adolescent obesity cases are estimated to reach 49.5 million cases worldwide by 2030. Nutrition education interventions to increase knowledge about healthy snacks in adolescents are important as a form of obesity prevention in adolescents. Healthy snacks quartet is an educational media that is carried out with a group game method so that adolescents feel comfortable in the learning process.

Objective: To determine the effect of healthy snacks quartet education on knowledge and sodium intake in overweight early adolescents.

Methods: This study is a quasi-experimental study with pre-posttest with control group design. The sample was purposively selected and 54 overweight adolescents were divided into a control group and two intervention groups. Education using healthy snacks quartet was conducted for 21 days from September to October 2023 in Makassar City. Data analysis was performed using Wilcoxon singed ranks test.

Results: There was a significant difference in adolescent knowledge with a p-value <0.05 in P1 (p=0.001) and P2 (p=0.000). However, there was no significant difference in sodium intake variables both in the control group (p=0.948), P1 (p=0.170) and P2 (p=0.170).

Conclusion: Education using healthy snacks quartet can increase knowledge about healthy snacks in overweight early adolescents but does not have a significant impact on sodium intake of overweight adolescents.

KEYWORDS: Natrium Intake; Nutrition Education; Knowledge; Overweight Adolescent
Influence of Breast Cancer Awareness Month on Public Interest of Breast Cancer in High-Income Countries Between 2012 and 2022: Google Trends Analysis
Authors: Ramadan Majed , Aboalola Doaa , Aouabdi Sihem , Alghamdi Tariq , Alsolami Mona , Samkari Alaa , Alsiary Rawiah
Published: August 2024

Background

Breast cancer is the most common cancer among women worldwide. High-income countries have a greater incidence and mortality rate of breast cancer than low-income countries. As a result, raising awareness about breast cancer is crucial in increasing the chances of early detection and treatment. Social media has evolved into an essential tool for Breast Cancer Awareness Month campaigns, allowing people to share their breast cancer stories and experiences while also providing a venue for education and support.

Objective

The aim of this study was to assess the level of public interest in searches linked to breast cancer among a sample of high-income nations with a sizable internet user base from 2012 to 2022. We also sought to compare the proportional search volume for breast cancer during Breast Cancer Awareness Month with that during other months of the year.

Methods

Google Trends was used to retrieve data on internet user search behaviors in the context of breast cancer from 2012 to 2022. Seven countries were evaluated in this study: Australia, Canada, Ireland, New Zealand, the United Kingdom, Saudi Arabia, and the United States, in addition to global data. Breast cancer relative search volume trends were analyzed annually, monthly, and weekly from 2012 to 2022. The annual percent change (APC) was calculated for each country and worldwide. Monthly and weekly data were used to identify potential trends.

Results

A fluctuating pattern in APC rates was observed, with a notable increase in 2018 and a significant decrease in 2020, particularly in Saudi Arabia. Monthly analysis revealed a consistent peak in search volume during October (Breast Cancer Awareness Month) each year. Weekly trends over a 20-year period indicated significant decreases in Australia, Canada, New Zealand, and the United States, while increases were noted in Ireland. Heatmap analysis further highlighted a consistent elevation in median search volume during October across all countries.

Conclusions

These findings underscore the impact of Breast Cancer Awareness Month and suggest potential influences of governmental COVID-19 pandemic control measures in 2020 on internet search behavior.
Barriers and Facilitators to the Use of Wearable Robots as Assistive Devices: Qualitative Study With Older Adults and Physiotherapists
Authors: Reicherzer Leah , Scheermesser Mandy , Kläy Adrian , Duarte Jaime E , Graf Eveline S
Published: August 2024

Background

Light wearable robots have the potential to assist older adults with mobility impairments in daily life by compensating for age-related decline in lower extremity strength. Physiotherapists may be the first point of contact for older adults with these devices.

Objective

The aims of this study were to explore views of older adults and physiotherapists on wearable robots as assistive devices for daily living and to identify the barriers and facilitators to their use.

Methods

Six older adults (aged 72‐88 years) tested a wearable robot (Myosuit) and participated in semistructured interviews. A focus group with 6 physiotherapists who had a minimum of 5 years of professional experience and specialized in geriatrics was conducted. Data were analyzed using thematic qualitative text analysis.

Results

Older adults perceived benefits and had positive use experiences, yet many saw no need to use the technology for themselves. Main barriers and facilitators to its use were the perception of usefulness, attitudes toward technology, ease of use, and environmental factors such as the support received. Physiotherapists named costs, reimbursement schemes, and complexity of the technology as limiting factors.

Conclusions

A light wearable robot—the Myosuit—was found to be acceptable to study participants as an assistive device. Although characteristics of the technology are important, the use and acceptance by older adults heavily depend on perceived usefulness and need.
Debate and Dilemmas Regarding Generative AI in Mental Health Care: Scoping Review
Authors: Xian Xuechang , Chang Angela , Xiang Yu-Tao , Liu Matthew Tingchi
Published: August 2024

Background

Mental disorders have ranked among the top 10 prevalent causes of burden on a global scale. Generative artificial intelligence (GAI) has emerged as a promising and innovative technological advancement that has significant potential in the field of mental health care. Nevertheless, there is a scarcity of research dedicated to examining and understanding the application landscape of GAI within this domain.

Objective

This review aims to inform the current state of GAI knowledge and identify its key uses in the mental health domain by consolidating relevant literature.

Methods

Records were searched within 8 reputable sources including Web of Science, PubMed, IEEE Xplore, medRxiv, bioRxiv, Google Scholar, CNKI and Wanfang databases between 2013 and 2023. Our focus was on original, empirical research with either English or Chinese publications that use GAI technologies to benefit mental health. For an exhaustive search, we also checked the studies cited by relevant literature. Two reviewers were responsible for the data selection process, and all the extracted data were synthesized and summarized for brief and in-depth analyses depending on the GAI approaches used (traditional retrieval and rule-based techniques vs advanced GAI techniques).

Results

In this review of 144 articles, 44 (30.6%) met the inclusion criteria for detailed analysis. Six key uses of advanced GAI emerged: mental disorder detection, counseling support, therapeutic application, clinical training, clinical decision-making support, and goal-driven optimization. Advanced GAI systems have been mainly focused on therapeutic applications (n=19, 43%) and counseling support (n=13, 30%), with clinical training being the least common. Most studies (n=28, 64%) focused broadly on mental health, while specific conditions such as anxiety (n=1, 2%), bipolar disorder (n=2, 5%), eating disorders (n=1, 2%), posttraumatic stress disorder (n=2, 5%), and schizophrenia (n=1, 2%) received limited attention. Despite prevalent use, the efficacy of ChatGPT in the detection of mental disorders remains insufficient. In addition, 100 articles on traditional GAI approaches were found, indicating diverse areas where advanced GAI could enhance mental health care.

Conclusions

This study provides a comprehensive overview of the use of GAI in mental health care, which serves as a valuable guide for future research, practical applications, and policy development in this domain. While GAI demonstrates promise in augmenting mental health care services, its inherent limitations emphasize its role as a supplementary tool rather than a replacement for trained mental health providers. A conscientious and ethical integration of GAI techniques is necessary, ensuring a balanced approach that maximizes benefits while mitigating potential challenges in mental health care practices.
Toward Safe and Confident Silver Drivers: Interview Study Investigating Older Adults’ Driving Practices
Authors: Kim Sunyoung , Sivangula Phaneendra
Published: August 2024

Background

As the aging population in the United States continues to increase rapidly, preserving the mobility and independence of older adults becomes increasingly critical for enabling aging in place successfully. While personal vehicular transport remains a popular choice among this demographic due to its provision of independence and control over their lives, age-related changes may heighten the risk of common driving errors and diminish driving abilities.

Objective

This study aims to investigate the driving practices of older adults and their efforts to maintain safe and confident driving habits. Specifically, we sought to identify the factors that positively and negatively influence older adults’ driving performance and confidence, as well as the existing efforts put into sustaining their driving abilities.

Methods

We recruited 20 adults aged ≥65 years who remained active drivers during the recruitment from the greater New York area. Then, we conducted semistructured interviews with them to examine their perceptions, needs, and challenges regarding safe and confident driving.

Results

Our findings uncovered a notable disparity between older adults’ self-perceived driving skills and the challenges they face, particularly caused by age-related limitations and health conditions such as vision and memory declines and medication routines. Drawing on these findings, we proposed strategies to bridge this gap and empower older adults to drive safely and confidently, including fostering a realistic understanding of their capabilities, encouraging open dialogue regarding their driving, encouraging regular assessments, and increasing awareness of available resources.

Conclusions

This study uncovered a noticeable disparity between the perceived driving competence of older adults and the actual challenges they confront while driving. This divergence underscores a significant need for better support beyond the existing aid available to preserve older adults’ driving skills. We hope that our recommendations will offer valuable insights for practitioners and scholars committed to enhancing the overall well-being and quality of life for older adults as they age in their homes.
Advancing Public Health Surveillance in Child Care Centers: Stakeholder-Informed Redesign and User Satisfaction Evaluation of the MCRISP Network
Authors: Gribbin William , Dejonge Peter , Rodseth Jakob , Hashikawa Andrew
Published: August 2024

Leveraging user feedback, we redesigned a novel disease monitoring utility to allow for bidirectional data flow and in this letter offer insights into that process as well as lessons learned.
The Impact of a Gamified Intervention on Daily Steps in Real-Life Conditions: Retrospective Analysis of 4800 Individuals (Preprint)
Authors: Mazéas Alexandre , Forestier Cyril , Harel Guillaume , Duclos Martine , Chalabaev Aïna
Published: August 2024

BACKGROUND

Digital interventions integrating gamification features hold promise to promote daily steps. However, results regarding the effectiveness of this type of intervention are heterogeneous and not yet confirmed in real-life contexts.

OBJECTIVE

This study aims to examine the effectiveness of a gamified intervention and its potential moderators in a large sample using real-world data. Specifically, we tested (1) whether a gamified intervention enhanced daily steps during the intervention and follow-up periods compared to baseline, (2) whether this enhancement was higher in participants in the intervention than in nonparticipants, and (3) what participant characteristics or intervention parameters moderated the effect of the program.

METHODS

Data from 4819 individuals who registered for a mobile health Kiplin program between 2019 and 2022 were retrospectively analyzed. In this intervention, participants could take part in one or several games in which their daily step count was tracked, allowing individuals to play with their overall activity. Nonparticipants were people who registered for the program but did not take part in the intervention and were considered as a control group. Daily step counts were measured via accelerometers embedded in either commercial wearables or smartphones of the participants. Exposure to the intervention, the intervention content, and participants’ characteristics were included in multilevel models to test the study objectives.

RESULTS

Participants in the intervention group demonstrated a significantly greater increase in mean daily steps from baseline than nonparticipants (P<.001). However, intervention effectiveness depended on participants’ initial physical activity. The daily steps of participants with <7500 baseline daily steps significantly improved from baseline both during the Kiplin intervention (+3291 daily steps) and the follow-up period (+945 daily steps), whereas participants with a higher baseline had no improvement or significant decreases in daily steps after the intervention. Age (P<.001) and exposure (P<.001) positively moderated the intervention effect.

CONCLUSIONS

In real-world settings and among a large sample, the Kiplin intervention was significantly effective in increasing the daily steps of participants from baseline during intervention and follow-up periods compared to nonparticipants. Interestingly, responses to the intervention differed based on participants’ initial steps, with the existence of a plateau effect. Drawing on the insights of self-determination theory, we can assume that the effect of gamification could depend of the initial motivation and activity of participants.
Influence of Breast Cancer Awareness Month on Public Interest of Breast Cancer in High-Income Countries Between 2012 and 2022: Google Trends Analysis (Preprint)
Authors: Ramadan Majed , Aboalola Doaa , Aouabdi Sihem , Alghamdi Tariq , Alsolami Mona , Samkari Alaa , Alsiary Rawiah
Published: August 2024

BACKGROUND

Breast cancer is the most common cancer among women worldwide. High-income countries have a greater incidence and mortality rate of breast cancer than low-income countries. As a result, raising awareness about breast cancer is crucial in increasing the chances of early detection and treatment. Social media has evolved into an essential tool for Breast Cancer Awareness Month campaigns, allowing people to share their breast cancer stories and experiences while also providing a venue for education and support.

OBJECTIVE

The aim of this study was to assess the level of public interest in searches linked to breast cancer among a sample of high-income nations with a sizable internet user base from 2012 to 2022. We also sought to compare the proportional search volume for breast cancer during Breast Cancer Awareness Month with that during other months of the year.

METHODS

Google Trends was used to retrieve data on internet user search behaviors in the context of breast cancer from 2012 to 2022. Seven countries were evaluated in this study: Australia, Canada, Ireland, New Zealand, the United Kingdom, Saudi Arabia, and the United States, in addition to global data. Breast cancer relative search volume trends were analyzed annually, monthly, and weekly from 2012 to 2022. The annual percent change (APC) was calculated for each country and worldwide. Monthly and weekly data were used to identify potential trends.

RESULTS

A fluctuating pattern in APC rates was observed, with a notable increase in 2018 and a significant decrease in 2020, particularly in Saudi Arabia. Monthly analysis revealed a consistent peak in search volume during October (Breast Cancer Awareness Month) each year. Weekly trends over a 20-year period indicated significant decreases in Australia, Canada, New Zealand, and the United States, while increases were noted in Ireland. Heatmap analysis further highlighted a consistent elevation in median search volume during October across all countries.

CONCLUSIONS

These findings underscore the impact of Breast Cancer Awareness Month and suggest potential influences of governmental COVID-19 pandemic control measures in 2020 on internet search behavior.
Resilience Informatics: Role of Informatics in Enabling and Promoting Public Health Resilience to Pandemics, Climate Change, and Other Stressors (Preprint)
Authors: Iyengar M Sriram , Block Ngaybe Maiya G , Gonzalez Myla , Arora Mona
Published: August 2024

UNSTRUCTURED

Climate change, local epidemics, future pandemics, and forced displacements pose significant public health threats worldwide. To cope successfully, people and communities are faced with the challenging task of developing resilience to these stressors. Our viewpoint is that the powerful capabilities of modern informatics technologies including artificial intelligence, biomedical and environmental sensors, augmented or virtual reality, data science, and other digital hardware or software, have great potential to promote, sustain, and support resilience in people and communities. However, there is no “one size fits all” solution for resilience. Solutions must match the specific effects of the stressor, cultural dimensions, social determinants of health, technology infrastructure, and many other factors.
Behavioral Intervention for Adults With Autism on Distribution of Attention in Triadic Conversations: A/B-Tested Pre-Post Study (Preprint)
Authors: Tepencelik Onur Necip , Wei Wenchuan , Luo Mirabel , Cosman Pamela , Dey Sujit
Published: August 2024

BACKGROUND

Cross-neurotype differences in social communication patterns contribute to high unemployment rates among adults with autism. Adults with autism can be unsuccessful in job searches or terminated from employment due to mismatches between their social attention behaviors and society’s expectations on workplace communication.

OBJECTIVE

We propose a behavioral intervention concerning distribution of attention in triadic (three-way) conversations. Specifically, the objective is to determine whether providing personalized feedback to each individual with autism based on an analysis of their attention distribution behavior during an initial conversation session would cause them to modify their orientation behavior in a subsequent conversation session.

METHODS

Our system uses an unobtrusive head orientation estimation model to track the focus of attention of each individual. Head orientation sequences from a conversation session are analyzed based on five statistical domains (eg, maximum exclusion duration and average contact duration) representing different types of attention distribution behavior. An intervention is provided to a participant if they exceeded the nonautistic average for that behavior by at least 2 SDs. The intervention uses data analysis and video modeling along with a constructive discussion about the targeted behaviors. Twenty-four individuals with autism with no intellectual disabilities participated in the study. The participants were divided into test and control groups of 12 participants each.

RESULTS

Based on their attention distribution behavior in the initial conversation session, 11 of the 12 participants in the test group received an intervention in at least one domain. Of the 11 participants who received the intervention, 10 showed improvement in at least one domain on which they received feedback. Independent t tests for larger test groups (df>15) confirmed that the group improvements are statistically significant compared with the corresponding controls (P<.05). Crawford-Howell t tests confirmed that 78% of the interventions resulted in significant improvements when compared individually against corresponding controls (P<.05). Additional t tests comparing the first conversation sessions of the test and control groups and comparing the first and second conversation sessions of the control group resulted in nonsignificant differences, pointing to the intervention being the main effect behind the behavioral changes displayed by the test group, as opposed to confounding effects or group differences.

CONCLUSIONS

Our proposed behavioral intervention offers a useful framework for practicing social attention behavior in multiparty conversations that are common in social and professional settings.

CLINICALTRIAL
Changes in compliance and microbial composition with smartphone-based telemonitoring for better oral health with toothbrushes: A 6-month randomized controlled trial (Preprint)
Authors: Kim Jaeyeon , Choi Yiseul , Song Yoolbin , Park Wonse
Published: August 2024

BACKGROUND

A toothbrush device that telemonitors toothbrushing is a technologically advanced toothbrushes that provide personalized feedback on an individual's toothbrushing habits and oral hygiene.

OBJECTIVE

This 6-month prospective randomized controlled trial aimed to verify the clinical effectiveness of using a telemonitoring toothbrush, an oscillating-rotating power toothbrush, and a manual toothbrush.

METHODS

This study was conducted at the Department of Advanced General Dentistry between January 2021 and May 2022 A total of 150 participants were enrolled and randomly divided into three groups (Oral-B® Genius 8000, ORT; Mombrush, ITT, and Manual toothbrush, MT). The relative plaque removal efficacy, reduction in halitosis, and changes in the oral microbiota were compared between the groups at four timepoints: at baseline and at one, three, and six months.

RESULTS

The Simple Plaque Score was decreased in the ITT group compared to that in the MT group (P<0.05); the Quigley-Hein Plaque Index was also decreased in the ITT group compared to that in the ORT and MT groups at different time points (P=0.000). However, there were no significant differences in halitosis (H2S and CH3SH) or high-risk periodontal microbiota between the groups at any timepoint. The ratio of caries-risk microbiota significantly increased in the MT group, whereas the ratio of anti-caries microbiota decreased (P<0.05).

CONCLUSIONS

Smart toothbrushes enable proper oral hygiene management for longer periods than manual toothbrushes. However, the interest in smart tooth brushing declined in recall after three months, and further research is needed to determine the appropriate feedback cycle and compliance with the application. Thus, smart toothbrushes with application and feedback interaction enable proper oral hygiene management than manual toothbrushes.

CLINICALTRIAL

Clinical Research Information Service (CRIS), Republic of Korea, KCT0009094.
Assessment of Land Capability and Zoning for Sustainable Urban Development in Ambon City
Authors: Lasaiba Mohammad Amin
Published: August 2024

The optimization strategy replaces ability-useful land with conservation-source power land, which may help with problem degradation. Investigate this to determine the level of land ability and the function area designation for good protection and cultivation in the Satuan Wilayah Pengembangan (SWP). The research method is descriptive and quantitative, with stepwise data collection and processing. Data collection is carried out through studies and literature from several agencies. Temporary spatial data analysis was conducted using Geographic Information System (GIS) software. The research findings underscore a significant aspect regarding land analysis, specifically about allocating areas for settlement purposes. The documented 3687.35 hectares identified as suitable for settlement development, alongside the approximately 11755.27 hectares allocated as buffer zones, highlight a limited portion of land deemed suitable for urban expansion within the studied region. This observation underscores the challenge of finding suitable and adequate spaces for urban development initiatives in Ambon City. Identifying such a confined area underscores the need for strategic urban planning that considers land constraints, such as the predominantly hilly terrain, to ensure balanced development, efficient land use, and the preservation of environmental integrity. Efforts toward optimizing these available areas for urban growth while concurrently focusing on conservation and ecological sustainability become imperative for Ambon City's future urban development trajectory. They created a barrier to physical land where hilly areas dominate the characteristics of the Ambon City area
Analisis Kriteria Jamak dan AHP untuk Evaluasi Kesesuaian Lokasi Pengembangan Kawasan Industri di Kabupaten Wonogiri
Authors: Salsabila Fadiya , Santosa Purnama Budi
Published: August 2024

Kabupaten Wonogiri merupakan kabupaten yang menempati urutan kelima sebagai kabupaten/kota terluas di Provinsi Jawa Tengah dengan area seluas kurang lebih 1800 km². Namun, pertumbuhan industri di wilayah ini belum begitu pesat sehingga perlu adanya pengembangan kawasan industri yang memenuhi standar dan arahan tata ruang wilayah. Penelitian ini dilakukan untuk menentukan lokasi yang sesuai untuk pengembangan kawasan industri kemudian mengevaluasi kesesuaiannya terhadap Rencana Tata Ruang Wilayah (RTRW). Metode yang digunakan adalah analisis spasial berbasis Sistem Informasi Geografis (SIG) serta pengambilan keputusan dengan metode Analytical Hierarchy Process (AHP). Kriteria penentuan lokasi yang digunakan dalam penelitian ini mengacu pada ketentuan dalam Peraturan Perindustrian Nomor 40/M-IND/PER/6/2016 tentang Pedoman Teknis Pembangunan Kawasan Industri. Proses analisis AHP dilakukan untuk mengetahui nilai bobot masing-masing kriteria. Pembobotan dilakukan dengan menggunakan perangkat lunak Expert Choice 11 dan menghasilkan rasio konsistensi sebesar 0,08. Hasil analisis menunjukkan bahwa terdapat lahan seluas 1356,806 ha yang berpotensi dikembangkan menjadi kawasan industri. Sedangkan overlay dengan RTRW menunjukkan bahwa lahan paling potensial terletak di Kecamatan Ngadirojo dengan luas 276,756 ha dan proporsi 99,240% dari seluruh kawasan peruntukan industri di wilayah tersebut.
In Vitro Evaluation of Cholesterol Lowering Properties of Plant Extract, Trigonella Foenum Graecum L.
Authors: Senthilkumar A. , Padayappa M. , Moorthi M.
Published: August 2024

Atherosclerosis is a disorder that causes the inner lining of arterial walls to accumulate lipids, cholesterol, and other chemicals. This restriction of blood flow results in high cholesterol, high blood pressure, high triglycerides, diabetes, obesity, and associated cardiovascular disorders. The current study sought to evaluate the ability of plant extract Trigonella foenum graecum ability to decrease cholesterol in vitro. Plant extracts were used at varying doses to block the activities of enzymes pancreatic lipase, glucose-6-phosphate dehydrogenase, and malic dehydrogenase. The extracts were then sequentially extracted using solvents including methanol, hexane, ethyl acetate, ethanol, and dichloromethane. According to the findings, the ethanol extract had the greatest significant hypolipidemic impact by reducing enzyme activities, and this was followed by the extracts of hexane, dichloromethane, and methanol. The ethyl acetate extracts showed the lowest hypolipidemic activity. These findings imply that the administration of several Trigonella foenum graecum plant extracts may have unique potential cholesterol-lowering qualities for reducing fat absorption via inhibiting pancreatic lipase.
Multi-criteria Decision Making Methods and sustainable Appliations in the Digital Age
Authors: Sutar Chandarani
Published: August 2024

Abstract: Designing a sustainable electrification system for remote places in developing countries is very complex while considering various factors such as technical, economic, environmental and social (TEES). Development of an efficient, rational, coherent and a translucent framework is required to address issues related to the requirement of energy needs based on the end user. The main goal of this research is to design a methodological framework based on decision analysis and optimized model with locally available energy sources. The new optimal renewable energy options are required to be used to minimize the fossil fuel dependency of electrical generation. Initially, suitable energy alternatives are selected by considering different criterion with multiple scenarios for decision analysis. The further optimal combination of energy sources evaluated for different possibilities. The new methodology of hybrid renewable optimization is applied to a rural place, Himachal Pradesh to illustrate its effectiveness based on metrological data
Regiones genómicas, genes y polimorfismos de un solo nucleótido en la resistencia a nematodos gastrointestinales en ovinos. Revisión
Authors: Villegas-Castañeda Marcela , Castañeda-Bustos Vielka Jeanethe , Bello-López Juan Manuel , Cruz-Cruz Clemente
Published: August 2024

Existen diversos factores que pueden modificar la productividad en los hatos ovinos, uno de ellos es la parasitosis gastrointestinal (GI) por nematodos, la cual puede generar pérdida de peso, retrasos en el crecimiento y en situaciones extremas la muerte. Las infecciones de parásitos involucran al sistema inmune para la resistencia o susceptibilidad, por lo que actualmente se buscan estrategias que sean eficientes a largo plazo para disminuir esta afectación. Una de estas estrategias es la ganadería de precisión, la cual consiste en la identificación y selección de animales genéticamente más resistentes, empleando para ello marcadores moleculares. El objetivo de esta revisión es reunir información novedosa en rasgos cuantitativos (QTL) y estudios de asociación del genoma completo (GWAS), que confirman la relevancia de algunas regiones o genes en la resistencia a la parasitosis gastrointestinal ovina. Así mismo, se analizó la posible relevancia de nuevas regiones para realizar mapeos más finos y encontrar conjuntos de polimorfismos que permitan una selección más eficiente, considerando al mismo tiempo, las condiciones particulares de los hatos ovinos.
Resistencia a la ivermectina en Rhipicephalus microplus (Acari: Ixodidae) en el noreste de México y factores de riesgo asociados
Authors: Moreno-Linares Samantha Abigail , García-Ponce Romario , Hernández-Escareño Jesús Jaime , Rodríguez-Ramírez Heidi Giselle , Villarreal-Villarreal José Pablo
Published: August 2024

Rhipicephalus microplus, es la especie parasitaria que más daño genera a la ganadería mexicana y global debido a las pérdidas directas e indirectas, como lo es el incremento de la multirresistencia y la resistencia cruzada. En la actualidad, son pocos los estudios que se tienen sobre la resistencia a lactonas macrocíclicas en México, siendo su mayoría en el sur. El presente estudio tuvo como objetivo evaluar el estado de la resistencia a ivermectina en R. microplus, en el noreste de México y factores de riesgo asociados a ésta. Se colectaron 20 poblaciones de Rhipicephalus microplus, en los estados de Veracruz, Nuevo León, Tamaulipas y San Luis Potosí, y se analizaron con la prueba de inmersión de larvas. Los datos de mortalidad se sometieron a un análisis Probit, estimándose las concentraciones letales (CL) del 50% y 99% y sus respectivos intervalos de confianza del 95% (IC95%) y para la determinación de los posibles factores de riesgo se realizó un análisis multivariado y tablas de contingencia de 2 x 2 para las variables de exposición, con un intervalo de confianza del 95%, y un modelo de regresión logística binomial para aquellas variables con una P≤0.05. El 80 % de las poblaciones analizadas presentaron resistencia con rangos de RR50= 2.07-11.14 y RR99= 3.03-47.93 (P≤0.05) y mediante la regresión logística binomial, se pudo observar que la variable frecuencia de tratamientos obtuvo una P≤0.0134, resultado que mostró ser significativo.
Modelo alternativo para medir la adopción de innovaciones: aplicación en el sistema apícola poblano
Authors: Farrera-Vázquez Irving César , Martínez-González Enrique Genaro , Santoyo-Cortés Vinicio Horacio , Aguilar-Gallegos Norman , Luna-Olea Reyna Azucena , Omaña-Silvestre José Miguel
Published: August 2024

Este trabajo tuvo como objetivo adaptar una herramienta metodológica capaz de mejorar la forma de obtener el Índice de Adopción de Innovaciones en el sistema apícola poblano. Se diseñó y aplicó un cuestionario a una muestra de 62 apicultores de donde se obtuvo información sobre el uso de innovaciones de manejo, genética, alimentación y sanidad, de la cual se definieron 32 variables originales y siete categorías de innovación. Se rediseñó y adaptó el índice de adopción de innovación (InAI) utilizando el proceso analítico jerárquico (PAJ), lo que facilitó la identificación de aspectos sociales de los apicultores y las innovaciones que contribuyen a mejorar la productividad de miel. Los resultados muestran que las innovaciones que más contribuyen a la producción son las contenidas en las categorías de ubicación del apiario y sanidad. Por otro lado, la evaluación del InAIalt, mostró ser una alternativa pertinente para la explicación del comportamiento del rendimiento por colmena, además de mostrar los porcentajes de aportación específicos sobre las innovaciones evaluadas, con lo cual se pueden calcular estimaciones más precisas y consistentes con los rendimientos esperados de la región.
Ensino de matemática: propostas pedagógicas, historiografia e diretrizes curriculares
Authors: Gutierre Liliane dos Santos , González Fredy Enrique , Silva Suzy Kelly da , Cury Fernando Guedes , Farias Raene Galvão , Flôr Anildo Soares , Medeiros Letícia de Azevêdo , Oliveira Adriel Gonçalves , Sousa Edson Silva de
Published: August 2024

Aqui encontram-se 5 encantadores artigos, que trazem contribuições relevantes para a formação inicial e continuada do professor de Matemática. Ele são resultados de pesquisas de alguns dos membros do Grupo Potiguar de Estudos e Pesquisas em Educação Matemática (GPEP) da Universidade Federal do Rio Grande do Norte (UFRN). A “coluna vertebral” de cada um dos artigos apresentados é: propostas pedagógicas, historiografia e diretrizes curriculares. Posto isto, o que mais dizer? Agora, é só desejar votos de uma boa leitura, pois as pesquisas no/do GPEP estão cada vez mais contribuindo com a Educação Matemática no RN e certamente no restante do país.
De Re Toponímica. Comunicaciones en Cantabria
Authors: Sojo y Lomba Fermín de , Villegas Cabredo Luis
Published: August 2024

Previo al texto completo de Sojo y Lomba se encuentra el estudio preliminar dividido en cuatro apartados: en el primero se hace un bosquejo biográfico de Fermín de Sojo y Lomba; seguidamente, se presenta ordenada por bloques temáticos su obra publicada, un total de 17 trabajos, y se comenta de un modo sintético las especificidades de los más importantes; en la tercera parte, se analiza detalladamente la singular obra sobre las comunicaciones en Cantabria que se recoge en este libro; finalmente, se mencionan los textos editados por Sojo y las referencias bibliográficas utilizadas en esta memoria.
Development of an Inclusive Visual Dictionary for Autistic Children Using Human-Computer Interaction
Authors:   Department of Computer Science  University of Ibadan Ibadan, Nigeria., Abiola Oladimeji A , Ojukwu, Enoch O.  , Ogunseye, Elizabeth O.  , Akinola, Solomon O.
Published: August 2024

Autism Spectrum Disorder (ASD) often face challenges in social interaction and communication. ASD communication resources will help in comprehensiveness, user-friendliness, and individual customization which this research addresses by developing a comprehensive Visual Dictionary (VD) designed specifically for their ASD needs. The research leverages on the visual strengths of children with ASD by creating a visually engaging and interactive dictionary using Figma tool due to its flexibility. The Visual Dictionary will provide a wide range of vocabulary and concepts relevant to children with ASD, promoting communication development, language skills, by employing Human-Computer Interaction (HCI) principles, the dictionary was designed in a user-friendly manner and accessible for children with varying abilities. The Visual Dictionary has the potential to improve communication skills, social interaction, and cognitive development in children with ASD. Keywords: Autism Spectrum Disorder (ASD), Visual Dictionary, Human Computer Interaction (HCI). Journal Reference Format: Abiola, O. A., Ojukwu, E.O., Ogunseye, E.O.& Akinola, S.O. (2024): Development of an Inclusive Visual Dictionary for Autistic Children Using Human-Computer Interaction. Social Informatics, Business, Politics, Law, Environmental Sciences & Technology Journal. Vol. 10, No. 2. Pp 31-41. www.isteams/socialinformaticsjournal. dx.doi.org/10.22624/AIMS/SIJ/V10N2P4
Clinical study of implant supported removable partial dentures
Authors: Park Won-Hee
Published: August 2024

OBJECTIVE The purpose of clinical study was to evaluate the survival of dental implants used in restoring patients with implant supported removable partial dentures (ISRPDs) of different configurations. MATERIALS AND METHODS The sample consisted of 20 consecutively treated partially edentulous patients, who, between 2003 and 2008, had a total of 84implants placed in different arch sites and who were treated with ISRPDs. The mean age was 57 years. Mean follow up time from delivery of ISRPDs was 3 years 2 months (range, 1 to 6 years). Osseointegration failure, postoperative complication of dental prosthesis, and the success rate of ISRPDs were retrospectively evaluated using clinical and radiographic examination. RESULT The overall implant survival rate was 100%. During follow up, the one clasp of removable partial denture was broken in 1 year11 months after prosthesis delivery. All patients were satisfied with their prosthesis. CONCLUSIONS Implant supported removable partial dentures could serve as favorable prognosis. Careful patient selection, with an appropriate maintenance and recall system, is recommended to obtain satisfactory results.