bluuebunny/crossref_metadata_2025 huggingface dataset:
PECULIARITIES OF COMORBID PAIN SYNDROME AND COGNITIVE DYSFUNCTION IN PATIENTS WITH MULTIPLE SCLEROSIS
Authors: Moskovko S.P. , Moskovko G.S. , Andriievska M.I. , Spivak Ya.V.
Published: January 2021

In this paper, we reviewed scientific sources on multiple sclerosis, analyzed the latest data on the peculiarities of cognitive dysfunction and comorbid pain syndrome in patients with multiple sclerosis. Multiple sclerosis belongs to the group of chronic progressive demyelinating diseases with a predominant lesion of the central nervous system. It affects over 2.5 million people worldwide and is considered as one of the most disabling neurological disorders. Symptoms range from physical ones including loss of vision, spasticity, bladder and bowel dysfunction, problems with walking and balance, fatigue and pain, to mental problems such as cognitive impairment, depression, and anxiety. Comorbid conditions have a significant impact on the quality of life of patients with multiple sclerosis. This evokes considerable scientific interest, since their presence can cause a delay in diagnosis, change the progression of neurological deficits, reduce physical activity and increase the severity of symptoms of the underlying disease. One of the most common comorbid conditions associated with multiple sclerosis is pain. The prevalence of pain syndrome ranges from 29% to 86%. Patients can consider pain as one of the first symptoms of multiple sclerosis. Moreover, in the treatment and diagnosis of multiple sclerosis, in most cases, the state of cognition is missed or neglected, but it always accompanies the patients in the form of cognitive disorders of varying severity. Cognitive function is understood as the most complex mechanism by which the process of rational cognition of the environment and interaction with it is carried out. Both a series of cognitive tests for multiple sclerosis and an MRI evaluation of gray matter atrophy can help to assess the state of cognition. Also, an additional diagnostic method is transcranial magnetic stimulation, with which it is possible to create a model for mapping the cerebral cortex using evoked motor potentials. Thus, the analysis of the literature has shown that the issues of the influence of comorbidity and cognitive dysfunction on the course of multiple sclerosis, the relationship of the onset of multiple sclerosis with comorbid conditions, and the correlation of neurological deficit with the cognitive ability of patients are not studied completely yet.
THIOZOLIDINEDIONES IN THE TREATMENT OF PATIENTS WITH EXTENSIVE PSORIASIS AND CONCOMITANT ALIMENTARY OBESITY
Authors: Yemchenko Ya.O. , Ishcheikin K.Ye. , Kaidashev I.P.
Published: January 2021

Psoriasis is one of the most common chronic recurrent systemic autoimmune multifactorial diseases, affected the skin, joints, internal organs and systems of the body. Despite the significant prevalence of psoriasis and a large number of studies devoted this problem there is still no single view on the pathogenesis of this dermatosis. To clear up the pathogenesis of psoriasis, it seems to be reasonable to focus on the common comorbidities or multimorbidities, which may occur in the course of psoriasis, as this issue is still insufficiently studied. Recent reports have proven the evidences of indisputable link between psoriasis and obesity. The scientific literature extensively covers the issues of identical pathogenetic mechanisms of inflammatory processes in psoriasis and obesity. Given the current data on the role of systemic inflammation underlying the development of both psoriasis and obesity, the study of molecular mechanisms of its development and in particularly the role of proinflammatory nuclear transcription factors, thiazolidinediones have been found out as pathogenetically justified medicine of choice for the therapy of these diseases. In this study, we determined the effectiveness of using 30 mg of pioglitazone daily for 6 months in the course of treatment for patients with extensive psoriasis vulgaris of moderate severity, who were also diagnosed as having concomitant grade І-ІІ alimentary obesity that was supported by clinical and immunological findings evidenced of systemic inflammation. Analyzing the results obtained, we have found out the prolonged therapy with pioglitazone leads to a decrease in systemic inflammation and contributes to a milder recurrent course of psoriasis.
Računalniško podprta stilometrična analiza pripovedne literature Janeza Ciglerja in Christopha Schmida v slovenščini
Authors: Žejn Andrejka
Published: January 2021

V
tridesetih letih 19. stoletja je nastala prva (izvirna) slovenska pripoved Sreča v nesreči (1836) avtorja Janeza
Ciglerja. Raziskovalci slovenske literature so velik vpliv na nastanek tega
dela pripisovali bavarskemu pisatelju Christophu Schmidu, tako v vsebini kot
strukturi, ideji in pripovednemu slogu, pa tudi sledenju duhu časa in
upoštevanju tradicije. Podrobneje so se posvečali zlasti vsebinskim
primerjavam, ne pa tudi analizam podobnosti stila. S paketom Stylo v
statističnem programskem okolju R za napredne stilistične analize zbirk besedil
smo zato izvedli stilometrično analizo Ciglerjevih in Schmidovih prevedenih del
ter nekaterih prevodov pripovedne literature obravnavanega obdobja. Ob
upoštevanju določenih omejitev, kot so omejena količina besedil, prevedena in
izvirna literatura in žanrska raznolikost, je analiza potrdila izviren
Ciglerjev slog in odprla nova vprašanja glede avtorstva nekaterih del.
Revisionism in Poetry
Authors: Sorel Sanjin
Published: January 2021

The article identifies the ways/procedures of revisionism in poetry. Not only does the exclusion of the poetry of Goran Babić from the national corpus not correspond with its poetic complexity and value, but it is also ethically inconsistent. Revisionism follows a national identity path according to which literature with clearly expressed views on socialism cannot fully exist within the history of poetry. Politics has taken the place of poetics.
Nogomet kao sredstvo nacionalne identifikacije Hrvata u Kraljevini SHS-u/Jugoslaviji i socijalističkoj Jugoslaviji
Authors: Kovačić Davor
Published: January 2021

Pogrješno je razmišljanje da je nogomet samo tjelesno kretanje, grubo natjeravanje suparnika, jer je on često više od igre. Nogomet je suvremeni socijalni fenomen i stanje u nogometu često je pokazatelj stanja u društvu i politici. Na hrvatskim i općenito južnoslavenskim prostorima nogomet je od samoga početka bio najpopularniji sport i privlačio je najveći broj gledatelja te izazivao veliko zanimanje javnosti. Nogomet nikada nije samo nogomet, uvijek je politiziran i kroz njega se zrcale odnosi u društvu uopće te je na neki način rendgen svega onoga što se u društvu događa. U članku je prikazano kako je nogomet u Kraljevini SHS-u/Jugoslaviji i u socijalističkoj Jugoslaviji bio sredstvo za izražavanje hrvatskoga etničkoga i nacionalnoga identiteta uslijed političkih sporova i podjela.
Adsorption behaviors of salivary pellicle proteins onto denture base metals using 27-MHz quartz crystal microbalance
Authors: Hirota Masatsugu , Hayakawa Tohru
Published: January 2021

BACKGROUND: The adsorption of salivary pellicle proteins onto the material surface is key for denture plaque formation. OBJECTIVE: We aimed to investigate the adsorption of bovine serum albumin (BSA) and mucin (MCN) onto denture base metal materials using a 27-MHz quartz crystal microbalance (QCM) method. METHODS: A gold (Au), titanium (Ti), and cobalt chromium alloy (Co–Cr) sensors were employed for QCM measurements. Adsorbed amounts of BSA or MCN were calculated by observing the frequency decrease, and the apparent reaction rate, kobs, was obtained by the curve fitting of the frequency shift against the adsorption time. RESULTS: The adsorbed amounts of BSA on Ti were significantly lower than those on Au and Co–Cr. For MCN adsorption, Au showed significantly greater amounts of adsorption than Co–Cr. The kobs of Ti for BSA adsorption was significantly smaller than for the Co–Cr. The kobs of Ti, and Co–Cr for MCN adsorption were significantly smaller than for the Au. A clear correlation was not determined between adsorbed amounts of BSA or MCN onto each sensor and the surface topography or contact angles. CONCLUSIONS: The difference of denture base metals and the difference of salivary proteins influences the adsorption behavior of salivary proteins.
Sixty Years – and More – of Data Modelling
Authors: Jaakkola Hannu , Thalheim Bernhard
Published: January 2021

Data (conceptual, data, information, knowledge) modelling is still the work of an artisan, i.e. an art in the best case, made by humans, because of the need for human intelligence. Data modelling is an essential part of Information System (IS) design, specifying how data is implemented as part of an IS. The principles of data modelling follow the evolution of IS development paradigms, and these in turn follow the progress of technological changes in computing. Although technology has changed a lot during the decades of commercial use of computers – since the early 1950s to now, close to 70 years – data modelling is still based on the same basic principles as decades ago. Or is it really so? Finding the answer to this question was the main motivation to start writing this paper. Since the future is more interesting than the past, we set our research problem to be “What are the challenges for data modelling in the future?”. The reason for this is that we see some significant changes in the future in the data modelling sector which we wanted to examine. However, the future is a continuum of the past. The future cannot be fully understood without understanding the past. Humans also tend to forget the details of the past. Even the most remarkable innovations from the past have become part of the new normal. Consequently, at the beginning of our paper we look shortly at the progress of data modelling during the era of commercial computing. Our focus is on the recent past and we look at the technological changes that have been of key importance in data modelling in the role of triggers and enablers. To find the answer to our research question, we retrieved some recent studies handling the future of data modelling and analyse the challenges found in these sources. The paper is concluded by some future paradigms. In general, the big changes seem to be the growing importance of Artificial Intelligence (AI) and machine learning (ML) as its fuel. AI not only conducts algorithmic rule-based routines, it has learning capability, which makes it more intelligent and adaptable, and able to compete with human intelligence, even in data management tasks.
A Cross-Cultural Newspaper Content Analysis: Smart Cities in Japanese and Slovenian Newspapers
Authors: Sato Yukiko , Brückner Stefan , Pušnik Maja
Published: January 2021

The realisation of smart cities has attracted much attention in recent years from private and governmental actors, as a means to make cities more efficient, climate friendly and socially inclusive through the use of modern technology. However, few studies examine how smart cities are framed and understood within the public sphere. The aim of this study is to compare how domestic smart city initiatives are reported in the news of their respective countries, and to clarify the differences and similarities in media content. In this paper, we present the initial findings of our planned long-term comparative news content analysis. As a first step, we analysed national newspaper articles published between 2011 and 2019 in Japan and Slovenia. Our corpus consists of 41 Japanese and 20 Slovenian articles, written in relation to domestic smart city initiatives. In total, we identified 14 themes, five of which were common in both countries, while the remaining nine appeared exclusively in the news of one country. Our conclusions indicate that the news in both countries differ in what application domains of Smart Cities are discussed (e.g. natural resources and energy, transportation and mobility). We establish a procedure for further cross-cultural analyses, necessary to understand how smart cities are framed in the public sphere. Thereby, we contribute to further discussion on the nature and definition of smart cities and how they are communicated.
Age-Related Tau Burden and Cognitive Deficits Are Attenuated in KLOTHO KL-VS Heterozygotes
Authors: Driscoll Ira , Ma Yue , Gallagher Catherine L. , Johnson Sterling C. , Asthana Sanjay , Hermann Bruce P. , Sager Mark A. , Blennow Kaj , Zetterberg Henrik , Carlsson Cynthia M. , Engelman Corinne D. , Dubal Dena B. , Okonkwo Ozioma C.
Published: January 2021

Background:

Identification of new genetic variants that modify Alzheimer’s disease (AD) risk will elucidate novel targets for curbing the disease progression or delaying symptom onset.

Objective:

To examine whether the functionally advantageous KLOTHO gene KL-VS variant attenuates age-related alteration in cerebrospinal fluid (CSF) biomarkers or cognitive function in middle-aged and older adults enriched for AD risk.

Methods:

Sample included non-demented adults (N = 225, mean age = 63±8, 68% women) from the Wisconsin Registry for Alzheimer’s Prevention and the Wisconsin Alzheimer’s Disease Research Center who were genotyped for KL-VS, underwent CSF sampling and had neuropsychological testing data available proximal to CSF draw. Covariate-adjusted multivariate regression examined relationships between age group (Younger versus Older; mean split at 63 years), AD biomarkers, and neuropsychological performance tapping memory and executive function, and whether these relationships differed between KL-VS non-carriers (KL-VSNC) and heterozygote (KL-VSHET).

Results:

In the pooled analyses, older age was associated with higher levels of total tau (tTau), phosphorylated tau (pTau), and their respective ratios to amyloid-β (Aβ)42 (ps ≤ 0.002), and with poorer performance on neuropsychological tests (ps ≤ 0.001). In the stratified analyses, KL-VSNC exhibited this age-related pattern of associations with CSF biomarkers (all ps ≤ 0.001), and memory and executive function (ps ≤ 0.003), which were attenuated in KL-VSHET (ps ≥ 0.14).

Conclusion:

Worse memory and executive function, and higher tau burden with age were attenuated in carriers of a functionally advantageous KLOTHO variant. KL-VS heterozygosity seems to be protective against age-related cognitive and biomolecular alterations that confer risk for AD.
Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort
Authors: Atkins Janice L. , Pilling Luke C. , Heales Christine J. , Savage Sharon , Kuo Chia-Ling , Kuchel George A. , Steffens David C. , Melzer David
Published: January 2021

Background:

Brain iron deposition occurs in dementia. In European ancestry populations, the HFE p.C282Y variant can cause iron overload and hemochromatosis, mostly in homozygous males.

Objective:

To estimate p.C282Y associations with brain MRI features plus incident dementia diagnoses during follow-up in a large community cohort.

Methods:

UK Biobank participants with follow-up hospitalization records (mean 10.5 years). MRI in 206 p.C282Y homozygotes versus 23,349 without variants, including T2* measures (lower values indicating more iron).

Results:

European ancestry participants included 2,890 p.C282Y homozygotes. Male p.C282Y homozygotes had lower T2* measures in areas including the putamen, thalamus, and hippocampus, compared to no HFE mutations. Incident dementia was more common in p.C282Y homozygous men (Hazard Ratio HR = 1.83; 95% CI 1.23 to 2.72, p = 0.003), as was delirium. There were no associations in homozygote women or in heterozygotes.

Conclusion:

Studies are needed of whether early iron reduction prevents or slows related brain pathologies in male HFE p.C282Y homozygotes.
Correlation Between Brain 18F-AV45 and 18F-FDG PET Distribution Characteristics and Cognitive Function in Patients with Mild and Moderate Alzheimer’s Disease
Authors: Jing Jiaojiao , Zhang Feng , Zhao Li , Xie Jinghui , Chen Jianwen , Zhong Rujia , Zhang Yanjun , Dong Chunbo
Published: January 2021

Background:

Florbetapir (AV45) and fluorodeoxyglucose (FDG) PET imaging are valuable techniques to detect the amyloid-β (Aβ) load and brain glucose metabolism in patients with Alzheimer’s disease (AD).

Objective:

The purpose of this study is to access the characteristics of Aβ load and FDG metabolism in brain for further investigating their relationships with cognitive impairment in AD patients.

Methods:

Twenty-seven patients with AD (average 70.6 years old, N = 13 male, N = 14 female) were enrolled in this study. These AD patients underwent the standard clinical assessment and received detailed imaging examinations of the nervous system by using Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MOCA), 18F-AV45, and 18F-FDG PET scans.

Results:

Of 27 AD patients, 22 patients (81.5%) showed significantly increases in Aβ load and 26 patients (96.3%) had significantly reductions in FDG metabolism. The moderate AD patients had more brain areas of reduced FDG metabolism and more severe reductions in some regions compared to mild AD patients, with no differences in Aβ load observed. Moreover, the range and degree of reduced FDG metabolism in several regions were positively correlated with the total score of MMSE or MOCA, whereas the range of Aβ load did not. No correlation was found between the range of Aβ load and the range of reduced FDG metabolism in this study.

Conclusion:

The reduction in FDG metabolisms captured by 18F-FDG imaging can be used as a potential biomarker for AD diagnosis in the future. 18F-AV45 imaging did not present valuable evidence for evaluating AD patient in this study.
The R-package surveysd: Estimating standard errors for complex surveys with a rotating panel design
Authors: Gussenbauer Johannes , de Cillia Gregor
Published: January 2021

Surveys with a rotating panel design are a prominent tool for producing more efficient estimates for indicators regarding trends or net changes over time. Variance estimation for net changes becomes however more complicated due to a possibly high correlation between the panel waves. Therefore, these estimates are quite burdensome to produce with traditional means. With the R-package surveysd, we present a tool which supports a straightforward way for producing estimates and corresponding standard errors for complex surveys with a rotating panel design. The package uses bootstrap techniques which incorporate the panel design and thus makes it easy to estimate standard errors. In addition the package supports a method for producing more efficient estimates by cumulating multiple consecutive sample waves. This method can lead to a significant decrease in variance assuming that structural patterns for the indicator in question remain fairly robust over time. The usability of the package and variance improvement, using this bootstrap methodology, is demonstrated on data from the user database (UDB) for the EU Statistics on Income and Living Conditions of selected countries with various sampling designs.
Penerapan Akuntansi Kewajiban Provisi Lingkungan Pada Perusahaan Sektor Industri Semen
Authors: Guntara Ronald , Ardiani Ni Luh Gede Desy
Published: January 2021

Penelitian ini bertujuan untuk mengulas penerapan akuntansi kewajiban provisi lingkungan pada perusahaan sektor industri semen dengan mengambil objek PT Indocement Tunggal Prakarsa Tbk, PT Semen Baturaja Tbk, dan PT Semen Indonesia Tbk. Tinjauan yang dilakukan dalam penelitian ini meliputi pengakuan, pengukuran, pencatatan, dan penyajian kewajiban provisi lingkungan pada perusahaan sektor industri semen sesuai dengan standar akuntansi yang berlaku di Indonesia. Metode penelitian yang digunakan dalam penelitian ini adalah menggunakan metode kualitatif dengan content analysis dan menggunakan data informasi laporan keuangan perusahaan yang diakses melalui laman Bursa Efek Indonesia (www.idx.co.id). Penelitian ini menyimpulkan bahwa perlakuan akuntansi yang diterapkan oleh PT Indocement Tunggal Prakarsa Tbk, PT Semen Baturaja Tbk, dan PT Semen Indonesia Tbk secara umum sudah sesuai dengan perlakuan akuntansi kewajiban provisi lingkungan yang terdapat pada Pernyataan Standar Akuntansi Keuangan (PSAK) Nomor 57 (2014) seperti pengukuran, pencatatan, dan penyajian kewajiban provisi lingkungan. Tetapi dalam pengakuan hanya PT Semen Baturaja Tbk yang mengakui provisi tersebut pada laporan posisi keuangan konsolidasian sebagai provisi reklamasi dan pasca tambang. PT Indocement Tunggal Prakarsa Tbk dan PT Semen Indonesia Tbk mengakui provisi tersebut sebagai provisi jangka panjang, sehingga pembaca tidak langsung tahu bahwa provisi tersebut adalah provisi lingkungan.
EVALUATION OF SERUM INTERLEUKIN-10 LEVELS AS A BIOMARKER OF GLYCEMIC ALTERATION IN CHRONIC PERIODONTITIS AND TYPE 2 DIABETES MELLITUS: BIO-CHEMICAL STUDY
Authors: Yadav Aditi , Shukla Pradeep , Dahiya Varun , Malhotra Gaurav , Kataria Prerna , Dagar Mona
Published: January 2021

Aim: Chronic periodontal disease (CPD) and type 2 diabetes mellitus (T2DM) share common pathogenic pathways. This study was aimed to estimate levels the of serum interleukin (IL?10), an anti?inflammatory cytokine also associated with T2DM and evaluate its association with hyperglycemia.

Materials and Methods: This investigation involved seventy five participants (55 males, 20 females, 30-55 age group) divided into three groups comprising 25 participants each: Group 1 (healthy controls), Group 2 (CPD patients) and Group 3 (T2DM patients with CPD) . Plaque index, gingival index, probing pocket depths (PPD), clinical attachment loss, bleeding on probing, random blood sugar, glycosylated hemoglobin (HbA1c), and serum IL?10 was measured.

Results: Interleukin?10 was detected in all three groups. Statistically significant (P < 0.05) differences were observed in most of the variables in all groups. IL?10 correlated significantly with PPD in Group 1 and with HbA1c in Group 3. IL?10 levels were lowest in Group 2.

Conclusion: Low IL?10 levels associated with high HbA1c. Pathogenic mechanisms of CPD seem to regulate IL?10. Serum IL?10 levels may be one of the predictors of hyperglycemia.

Key words: Chronic periodontitis, diabetes mellitus, glycosylated, hemoglobin A, interleukin?10, type 2 diabetes mellitus
General Requirements for Secret Investigative (Search) Actions: Procedural Characteristics
Authors: Конюшенко Я. Ю.
Published: January 2021

A comprehensive study of the provisions of the Criminal Procedural Code of Ukraine, which regulate the general requirements for secret investigative (search) actions, has been carried out. A comparative analysis of the legislative provisions on the issue has been carried out, which made it possible to distinguish seven groups of general requirements for the implementation of secret investigative (search) actions. The first general requirement of secret investigative (search) actions includes restrictions on their use in criminal proceedings, as they are carried out only in cases where information about the criminal offense and the person who committed it, cannot be obtained in any other way. The second general requirement for conducting secret investigative (search) actions includes restrictions on their use in criminal proceedings, in particular the fact that they are conducted exclusively in criminal proceedings for grave or especially grave offenses. The third general requirement for conducting secret investigative (search) actions is that the legal basis for their implementation is a lawful, reasoned and motivated decision of the investigating judge, issued at the request of the prosecutor or investigator, agreed with the prosecutor. The fourth general requirement for conducting secret investigative (search) actions is that the investigating judge of the appellate court has the right to make the decision to implement them, where the pre-trial investigation agency is within the territorial jurisdiction of that judge. The fifth general requirement includes rules concerning the content of the application for a permit to conduct secret investigative (search) action, the procedure for its consideration by the investigating judge and the content of the decision of the investigating judge. The sixth general requirement for conducting secret investigative (search) actions includes rules that set deadlines for their implementation. The seventh general requirement for conducting secret investigative (search) action includes the rule that the investigator, the interrogator conducting the pre-trial investigation, or, on his behalf or on behalf of the prosecutor, authorized operative units have the right to conduct secret investigative (search) actions.
Legal Principles of Procedural Activity and Interaction of Employees of Operative Divisions at Execution of Instructions of Interrogators, Investigators, Prosecutors in Regard to Carrying out Secret Investigative (Search) Actions
Authors: Юхно О. О.
Published: January 2021

The author of the article provides a retrospective analysis of the provisions of legislative acts of Ukraine, decisions of the Constitutional Court of Ukraine and the European Court of Human Rights, as well as some national criminal procedural legislation and departmental regulations on legal grounds for procedural activities and interaction of operative units to execute written instructions of interrogators, investigators, prosecutors on investigative (search) actions and secret investigative (search) actions. The author has made a retrospective analysis of the introduction of this amendment to the Criminal Procedural Code of Ukraine since 2012, as well as the legal grounds for its use in pre-trial investigation and has focused on the conclusions about its significant prevalence in law enforcement activities of pre-trial investigation, and in connection with recent amendments in the legislation also in the initial practice of the inquiry agencies of the National Police of Ukraine. The author researched positions of scholars and representatives of scientific schools in relation to the conceptual apparatus and the essence of the concept of “interaction” in general, as well as “interaction” between pre-trial investigation and inquiry agencies and operative police units in this direction. Special attention has been paid to the study of the peculiarities of forms of interaction and its subjects in criminal proceedings, as well as the existing legislative and practical issues concerning the compliance with operative deadlines of police orders of interrogators, investigators and prosecutors and has suggested the ways to solve them in practice and, in particular, at the legislative level.

Additionally, it has been established, substantiated and focused on theoretical and applied improvement of the use of such a feature in law enforcement activities that operative staff, in carrying out written instructions of interrogators, investigators and prosecutors on the conduction of investigative and secret investigative actions, has procedural rights of the investigator and interrogator. Based on this, the author also offers propositions and recommendations in this area.
Estimation of Monthly Total Dissolved Solids Using ANN and LS-SVM Techniques in the Aji Chay River, Iran
Authors: JannatKhah Mahdieh , Akbari Abolghasem , Bagheri Basmanji Aida , Rahmani Ebrahim , Peter Cox Jonathan
Published: January 2021

This research follows on from diverse international efforts to safeguard one of the largest natural lakes in the world, Urmia lake in North West Iran. In this research two new numerical packages based on Artificial Neural Networks (ANN) and the Least Square Support Vector Machine (LS-SVM) models were developed to estimate monthly Total Dissolved Solid (TDS) in the Aji Chay River, one the main tributaries of Urmia lake, Iran. A feed forward back propagation (FFB) model was used to obtain a set of coefficients for a linear model, and the radial basis function (RBF) kernel was employed for the LS-SVM model. The input data sets of both the ANN and LS-SVM models consists of six water quality parameters: TDS, Mg2+, Na+, Ca2+, Cl-, and SO4 2-, all collected on a monthly time scale over a period of 30 years from the Vanyar and Zarnagh stations, in the Aji Chay watershed. The research demonstrated that both models can effectively predict the variability of TDS, but for the Vanyar station with the ANN model (giving an R2 value of 0.913 and RMSE of 0.0032, a Nash-Sutcliffe Efficiency (NSE) coefficient 0.812 and as such has a more efficient and accurate estimation when compared to the LS-SVM model with R2=0.871 and RMSE =0.097 and NSE=0.86. The analysis of Zarnagh station data shows R2=0.853 and RMSE=0.0162, NSE= 0.854 for SVM and R2=0.903 and RMSE =0.0091 and NSE=0.85 for ANN.
Aplikasi Model Keperawatan Levine Pada Asuhan Keperawatan Pada Anak Dengan Masalah Oksigenasi
Authors: Mawaddah Ely , Nurhaeni Nani , Wanda Dessie
Published: January 2021

Masalah oksigenasi merupakan kondisi yang sering ditemui pada anak. Infeksi saluran nafas, kondisi sistem respirasi yang masih immatur, usia anak dan perubahan musim mempengaruhi penyakit pernafasan pada anak sehingga menyebabkan anak membutuhkan perawatan di rumah sakit. Perawat membantu pemenuhan masalah pemenuhan kebutuhan oksigenasi agar tubuh mampu melanjutkan fungsi. Aplikasi Model Konservasi Levine bertujuan untuk memberikan tindakan keperawatan berdasarkan empat prinsip: konservasi energi, konservasi integritas struktur, konservasi integritas personal dan konservasi integritas sosial.  Studi ini menggunakan desain studi kasus. Kasus yang diambil berjumlah 5 kasus di ruang infeksi anak RSUPN Cipto Mangunkusumo. Sampel yang diambil adalah anak dengan masalah oksigenasi. Data diambil dari catatan medis dan perawatan pasien serta pemeriksaan fisik dan observasi pasien. Hasil yang diperoleh menunjukkan bahwa Model konservasi Levine memberikan panduan berpikir yang sistematis dalam pemberian asuhan keperawatan dan dapat diterapkan dalam perawatan anak dengan masalah oksigenasi. Perawat dapat menerapkan model konservasi levine dan digabungkan dengan model lainnya.
PENGARUH KEPUASAN KERJA DAN KOMUNIKASI TERHADAP KINERJA KARYAWAN
Authors: D Galih Arisca , Firdaus Muhammad Azis , Rinda Rachmatullaily Tina Kartika
Published: January 2021

Penelitian ini bertujuan untuk Kepuasan Kerja dan Kesiapan Karyawan yang dilakukan oleh karyawan Bank BJB Cabang Kota Depok. Metode survei dalam penelitian ini menggunakan data primer yang diperoleh dari kuesioner dan data sekunder dari resmi Bank BJB Cabang Kota Depok di internet. Sampel dalam penelitian ini adalah 50 responden menggunakan teknik Quota Sampling. Metode penelitian menggunakan uji validitas dan reliabilitas, koefisien determinasi, regresi linier sederhana, berganda, uji normalitas dengan uji hipotesis simultan (F) dan parsial (T) dengan mengolah menggunakan aplikasi komputer. Hasil penelitian ini menunjukkan bahwa Kepuasan Kerja dan Komunikasi secara simultan berpengaruh positif terhadap Kinerja Karyawan.
PENGARUH KURS VALUTA ASING DAN INFLASI TERHADAP PENDAPATAN EKSPOR
Authors: Zulfikar Ahmad , Suharti Titing , Yudhawati Diah
Published: January 2021

Penelitian ini dilakukan untuk mengetahui pengaruh Kurs Valuta Asing dan Inflasi terhadap Pendapatan Ekspor periode tahun 2010 – 2018. Populasi penelitian ini adalah Bank Indonesia, Badan Pusat Statistik, Kementerian Perdagangan Republik Indonesia periode tahun 2010 – 2018. Variabel yang digunakan dalam penelitian ini adalah kurs valuta asing dan inflasi, sebagai variabel independen; pendapatan ekspor sebagai variabel dependen. Analisis data yang digunakan untuk menguji hipotesis dalam penelitian ini adalah analisis regresi sederhana, analisis regresi linier berganda, analisis koefisien korelasi, analisis koefisien determinasi dan uji hipotesis.
Hasil penelitian ini menunjukkan bahwa (1) Kurs Valuta Asing secara parsial tidak berpengaruh secara signifikan terhadap Pendapatan Ekspor. (2) Inflasi secara parsial tidak berpengaruh secara signifikan terhadap Pendapatan Ekspor. (3) Kurs Valuta Asing dan Inflasi secara simultan tidak berpengaruh secara signifikan terhadap Pendapatan Ekspor.
PENGARUH STRES KERJA DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN
Authors: Valendra Yosa , Agung Syahrum , Firdaus Muhamad Azis
Published: January 2021

Tujuan penelitian ini untuk mengetahui adakah pengaruh stres kerja dan lingkungan kerja terhadap kinerja karyawan. Dalam mengukur kinerja karyawan menggunakan skala dan indikator sebagai bahan dalam mengolah data. Metode penelitian yg digunakan adalah metode kuantitatif. Penelitian kuantitatif merupakan suatu penelitian yang analisisnya secara umum memakai analisis statistik. Pada penelitian ini juga digunakan jenis penelitian survey, yaitu penelitian yang mengambil sampel yang digunakan pada penelitian ini sebanyak 72 responden sesuai dengan rumus slovin. Dengan hasil penelitian kedua variabel (Stres Kerja dan Lingkungan Kerja) saling mempengaruhi kinerja karyawan. Hal ini dapat dibuktikan dengan hasil persamaan regresi yang di dapat oleh aplikasi pengolahan data SPSS adalah Y = 0.382+ -0,874 X1 + 0,001 X2. Dan sebesar 0,264 atau (0,264%) memberikan arti bahwa rendah peranan stress kerja lingkungan kerja berpengaruh terhadap kinerja selebihnya sebesa 73,6% berasal dari faktor-faktor lain yang juga mempengaruhi kinerja. Karena f-hitung sebesar 8082.488> F-tabel 3,13, maka Ha diterima. Maka dapat disimpulkan bahwa terdapat hubungan yang signifikan antara insentif dan lingkungan kerja secara simultan terhadap kinerja karyawan pada Dinas Pertanian Provinsi Kepulauan Bangka Belitung.
ANALISI RASIO KEUANGAN UNTUK MENGUKUR KINERJA KEUANGAN PADA BANK
Authors: Sari Nurmala , Supramono Supramono , Aminda Renea Shinta
Published: January 2021

Tujuan penelitian ini adalah untuk mengetahui dan mengevaluasi rasio keuangan dalam menilai kinerja keuangan pada PT. Bank Bukopin Tbk dan Bank Danamon Indonesia Tbk. Yang terdaftar di Bursa Efek Indonesia. Adapun pendekatan penelitian yang digunakan adalah pendekatan deskriptif. Sedangkan jenis data yang digunakan adalah data kuantitatif berupa angka dan sumber data yang digunakan yaitu Laporan Keuangan PT. Bank Bukopin Tbk dan PT Bank Danamon Indonesia Tbk. Dalam usaha mengatasi masalah keuangan tersebut, maka para pemimpin perusahaan tidak terlepas dari pengambilan keputusan. Sedangkan untuk mengambil suatu keputusan diperlukan data dan informasi yang relevan dan akurat, salah satu sumber informasi yang cukup penting dan dapat dipercaya yaitu laporan keuangan, berdasarkan laporan keuangan tersebut, manajemen atau pemimpin perusahaan dapat mengetahui kinerja keuangan perusahaan yang mereka pimpin, selain itu laporan keuangan merupakan data yang dapat dipakai untuk mengetahui posisi keuangan suatu perusahaan pada periode tertentu, biasanya dalam satu tahun buku. Berdasarkan Analisis Kinerja Rasio Keuangan bahwa secara keseluruhan kinerja keuangan PT Bank Bukopin Tbk dan Bank Danamon Indonesia Tbk pada umumnya cukup baik, hal ini dikarenakan hasil dari perhitungan ketiga rasio yang digunakan selalu fluktuatif, Akan tetapi laba bersih yang dihasilkan oleh perusahaan selalu menurun.
PENGARUH KERAGAMAN PRODUK DAN PELAYANAN TERHADAP LOYALITAS KONSUMEN
Authors: Lindawati Lindawati , Sume Syahlan A. , Muniroh Leny
Published: January 2021

Penelitian ini dilakukan di toko Makaroni Ngehe, bisnis yang bergerak di bidang kuliner. Hasil evaluasi dalam penelitian ini menunjukan bahwa langkah-langkah yang dilakukan oleh toko Makaroni Ngehe dalam mempertahankan loyalitas konsumen dengan memberikan keragaman produk dan pelayanan yang sesuai dengan kebutuhan konsumen. Hasil penelitian diperoleh persamaan regresi berganda Y = 11,737 + 0,046 X1 + 0,235 X2. Hasil analisis simultan (uji f) di dapatkan f hitung sebesar 3,478 dengan tingkat signifikan 0,035. Sedangkan dari hasil uji parsial (uji t) diperoleh t hitung untuk variabel Keragaman Produk 0,520 dan pelayanan 2,578. Simpulan dan saran dari penelitian ini adalah ada pengaruh secara parsial pada variabel Keragaman Produk (X1) terhadap Loyalitas Konsumen (Y), sedangkan pada variabel Pelayanan (X2) terhadap variabel Loyalitas Konsumen (Y) tidak ada pengaruh secara parsial.
PENGARUH HARGA, ULASAN, DAN TAMPILAN PRODUK TERHADAP KEPUTUSAN PEMBELIAN SECARA ONLINE
Authors: Pramono Agung , Eldine Achyar , Muniroh Leny
Published: January 2021

Penelitian ini bertujuan untuk mengetahui pengaruh harga, ulasan produk dan tampilan produk terhadap keputusan pembelian secara online (Studi kasus pada produk casing custom Rendevous Industries di Tokopedia). Jenis penelitian ini adalah kuantitatif dan teknik pengumpulan data survei dengan penyebaran kuesioner online. Sampel dalam penelitian ini sebanyak 96 responden yang diambil dengan teknik sampling purposive. Metode analisis data menggunakan analisis regresi linier berganda disertai uji F (simultan) dan uji t (parsial), koefisien determinasi dan uji hipotesis dengan menggunakan aplikasi komputer SPSS 24.0. Hasil pengujian menunjukan bahwa harga, ulasan dan tampilan produk berpengaruh secara positif dan signifikan terhadap keputusan pembelian secara online pada produk casing custom Rendevous Industries di Tokopedia. Faktor yang sangat berpengaruh terhadap keputusan pembelian secara online pada produk casing custom Rendevous Industries di Tokopedia adalah harga.
ANALISIS ECONOMIC VALUE ADDED (EVA) DAN MARKET VALUE ADDED (MVA DALAM MENILAI KINERJA KEUANGAN PERUSAHAAN PERUSAHAANASURANSI YANG GO PUBLIC
Authors: Yulyawati Suci , Nurhayati Immas , Yudhawati Diah
Published: January 2021

Penelitian dengan judul Analisis Economic Value Added (EVA) dan Market Value Added (MVA) Dalam Menilai Kinerja Keuangan Perusahaan Asuransi yang Go Public ini bertujuan (1) mengetahui kinerja keuangan perusahaan jika dukur dengan menggunakan metode Economic Value Added (EVA); (2) mengetahui kinerja keuangan perusahaan jika dukur dengan menggunakan metode Market Value Added (MVA). Periode yang digunakankan adalah periode 2013 – 2017. Populasi dalam penelitian ini adalah perusahaan asuransi yanggo public periode 2013-2017. Metode pengambilan sampel dengan teknik purposive sampling maka jumlah sampel penelitian ini sebanyak dua perusahaan. Berdasarkan hasil penelitian ini menunjukan bahwa (1) perolehan Economic Value Added (EVA) PT. Asuransi Bina Dana Arta Tbk dan PT. Lippo General Insurance Tbk pada umumnya mampu memberikan nilai tambah ekonomis bagi perusahaan dilihat dari EVA yang positif, meskipun PT. Lippo General Insurance Tbk sempat mengalami nilai EVA yang negatif pada tahun 2016 namun pada tahun selanjutnya terus menunjukan kinerja keuangan yang membaik (2) PT. Lippo GeneralInsurance Tbk dan PT. Asuransi Bina Dana Arta Tbk periode 2013 sampai 2016 mampu menghasilkan nilai MVA yang positif sehingga kedua perusahaan tersebut dinyatakan mampu menambah nilai pasar perusahaan serta menciptakan kekayaan bagi para pemegang saham (investor).
GAMBARAN PEMBERIAN ASI EKSKLUSIF TERHADAP KEJADIAN STUNTING PADA BALITA UMUR 24-60 BULAN DI KELURAHAN TANAH BARU BOGOR TAHUN 2018
Authors: Chairani Leila siti , Sari Merry maeta , Nasution Andreanda , Prastia Tika noor
Published: January 2021

Stunting merupakan kondisi kekurangan gizi secara kronis dimulai dari 1000 hari pertama kehidupan sehingga anak mengalami gangguan pertumbuhan dan perkembangan yang terlihat dari tinggi badan menurut umur di bawah batas normal. Stunting diakibatkan oleh asupan nutrisi yang tidak adekuat, praktek makan yang buruk dan seringnya terkena penyakit. Asupan nutrisi terbaik didapatkan dari pemberian ASI secara eksklusif. Tujuan penelitian ini adalah melihat gambaran karakteristik ibu dan balita, pemberian ASI eksklusif dan kejadian stunting pada balita umur 24-60 bulan di Kelurahan Tanah Baru Kota Bogor tahun 2018. Metode penelitian ini adalah studi deskriptif dengan teknik pengambilan data secara purposive sampling. Penelitian ini menggunakanuji univariat untuk melihat gambaran variabel. Hasil penelitian didapatkan ibu sebagian besar berada di sekitar umur 29 tahun, pendidikan terakhir ibu paling banyak adalah tamat SD sebesar 34,8%, pekerjaan ibu paling banyak sebagai ibu rumah tangga sebanyak 92,4%. Sebanyak 52,2%balita berjenis kelamin perempuan dan sebagian besar berumur di sekitar usia 39 bulan. Didapatkan cakupan pemberian ASI eksklusif sebesar 31,5% dan angka kejadian stunting sebesar 33,7% yangberarti kejadian stunting di Kelurahan Tanah Baru sudah menjadi masalah kesehatan masyarakat.
HUBUNGAN MUTU PELAYANAN KESEHATAN DENGAN KEPUASAN PASIEN PESERTA BPJS DI UNIT RAWAT INAP PUSKESMAS CIBUNGBULANG KABUPATEN BOGOR TAHUN 2018
Authors: Maulina Lisna , Madjid T. Abdul , Chotimah Indira
Published: January 2021

Kepuasan pasien adalah tingkat perasaan pasien yang timbul sebagai akibat dari kinerja pelayanan kesehatan yang diperolehnya setelah pasien membandingkan dengan apa yang diharapkannya. Service quality yang tinggi merupakan faktor terpentingnya agar tercapainya mutu pelayanan kesehatan di Puskesmas Cibungbulang Kabupaten Bogor. Tujuan penelitian ini untuk mengetahuihubungan mutu pelayanan kesehatan dengan kepuasan pasien di instalasi rawat inap. Penelitian ini menggunakan metode kuantitatif dengan desain penelitian cross sectional. Sampel yang diambil menggunakan teknik purposive sampling didapatkan 1,864 pasien di instalasi rawat inap. Intrumen penelitian menggunakan kuesioner. Data dianalisis mengunakan uji statistik Chi Square dengan tingkat kemaknaan p-value ? 0,05. Lokasi penelitan dilakukan pada Puskesmas Cibungbulang. Hasil penelitian ini menunjukan bahwa faktor tangible (p-value=0,125), faktor reliability (p-value = 0,285), dan faktor assurance (p-value = 0,702) tidak terdapat hubungan dengan kepuasan pasien di puskesmas cibungbulang. Sedangkan faktor responsiveness (p-value = 0,000) dan faktorempathy (p-value = 0,000) terdapat hubungan dengan kepuasan pasien di puskesmas cibungbulang.
EVALUASI PENERAPAN SISTEM INFORMASI MANAJEMAN PUSKESMAS (SIMPUS) MELALUI METODE PIECES LAYANAN KUNJUNGAN RAWAT JALAN PUSKESMAS BOGOR UTARA TAHUN 2018
Authors: Fikri Rahmatia Laelatul
Published: January 2021

Sebagai salah satu pelayanan kesehatan masyarakat pemerintah, Puskesmas Bogor Utara telah menggunakan Informasi Rekam Medis. Sistem untuk mencatat semua informasi dan data kesehatanmasyarakat. Puskesmas Bogor Utara menerapkan Sistem Informasi Manajeman Puskesmas (SIMPUS) pada bulan April 2016. Tujuan penelitian ini adalah untuk melakukan evaluasi Sistem Informasi Manajeman Puskesmas (SIMPUS) melalui metode PIECES Information, Economic, Control, Effeciency, Service kunjungan rawat jalan puskesmas Bogor utara tahun 2018. Jenis penelitian adalah penelitian deskriftif kuantitatif digunakan melalui kuesioner dengan pendekatancross sectional. Populasi dalam penelitian ini adalah 42 orang tenaga puskesmas. Sampel yang digunakan dalam penelitian ini didapat dengan teknik pengambilan sampel (teknik sampling) Nonprobability Sampling, Analisis data dilakukan secara univariat dan bivariat uji Chi Square padatingkat kemaknaan 95% (? = 0,05). Hasil penelitian menunjukan sistem informasi manajeman puskesmas memiliki keamanan kurang terkontrol, pelayanan yang dilakukan kurang maksimal karenapada saat proses pengambilan resep obat belum dilakukan secara cepat yang mengakibatkan pasien menunggu saat berobat. Penerapan Sistem Informasi Manajeman Puskesmas di Bogor Utara telah berjalan dengan baik. Peneliti menyarankan agar sistem informasi puskesmas lebih meningkatkanproses pelayanan kepada pasien agar pasien tidak menunggu terlalu lama dalam pengambilan resep obat. Untuk itu perlu ditingkatkan pelayanan SIMPUS agar lebih baik untuk kedepannya.
GAMBARAN SISTEM MANAJEMEN DALAM PELAKSANAAN PROGRAM ASI EKSKLUSIF DI WILAYAH KERJA PUSKESMAS BOGOR UTARA KOTA BOGOR TAHUN 2019
Authors: Amelia Elsa Novemi , Hidana Rachma , Pujiati Suci
Published: January 2021

Puskesmas Bogor Utara adalah salah satu Puskesmas dengan cakupan ASI eksklusif masih rendah yaitu pada tahun 2017 sebesar 34,6%, cakupan tersebut belum memenuhi target pemberian ASI 80%. Penelitian ini bertujuan untuk mengetahui sistem manajemen dalam pelaksanaan program ASIEksklusif di wilayah kerja Puskesmas Bogor Utara. Jenis penelitian ini adalah kualitatif. Populasi dalam penelitian ini adalah seluruh pelaksana program ASI eksklusif di Puskesmas Bogor Utara Kota Bogor. Sampel dalam penelitian ini menggunakan Purposive Sampling, yaitu salah satu tekniksampling non random sampling dimana peneliti menentukan pengambilan sampel dengan cara menetapkan ciri-ciri khusus yang sesuai dengan tujuan penelitian. Informan dibagi menjadi 2 kriteria yaitu Informan Kunci adalah 4 orang ibu yang memiliki bayi 0-6 bulan yang tinggal di wilayah kerja Puskesmas Bogor Utara. Informan inti adalah Kepala Puskesmas, Petugas Gizi danBidan koordinator pemegang program KIA (Kesehatan Ibu dan Anak) di Puskesmas Bogor Utara. Total sampel dalam penelitian ini berjumlah 7 informan. Teknik pengambilan data menggunakan teknik wawancara, observasi, dan dokumentasi. Hasil penelitian menunjukkan aspek input sudahmemadai, aspek proses sudah berjalan dengan baik, aspek output belum memenuhi target karena kurangnya kesadaran masyarakat. Saran yang diberikan meningkatkan peran dan fungsi petugasterutama petugas gizi, promkes dan KIA terutama dalam memberikan informasi tentang ASI eksklusif dan diharapkan semua pihak dapat mendukung pelaksanaannya
FAKTOR- FAKTOR YANG BERHUBUNGAN DENGAN PEMILIHAN METODE KONTRASEPSI SUNTIK PADA PESERTA KB AKTIF DI KELURAHAN MEKARWANGI KECAMATAN TANAH SAREAL KOTA BOGOR TAHUN 2019
Authors: Kusnadi Nadya Resti , Rachmania Wina , Pertiwi Fenti Dewi
Published: January 2021

Kontrasepsi suntik merupakan metode kontrasepsi yang mengandung hormone progestin dan esterogen yang merupakan salah satu cara atau alternative untuk mencegah ataupun menunda kehamilan. Penelitian ini bertujuan untuk mengetahui faktor- faktor yang berhubungan dengan pemilihan kontrasepsi suntik pada peserta KB aktif di Kelurahan Mekarwangi Kecamatan TanahSareal Kota Bogor tahun 2019. Penelitian ini adalah penelitian kuantitatif, menggunakan desain studi cross sectional dengan cara penyebaran kuesioner. Sampel dalam penelitian ini adalah 110 responden yang merupakan peserta Kb aktif di wilayah Kelurahan Mekarwangi dengan metode acak sederhana(system random sampling). Hasil penelitian ini menunjukkan 72, 7% memilih memakai kontrasepsi suntik.Analisis Bivariat yang berhubungan dengan pemilihan kontrasepsi suntik adalah umur denganp value= 0,006, Jumlah anak dengan p value= 0,001, dan Biaya pelayanan dengan p value = 0,007. Berdasarkan hasil dari penelitian ini, disarankan bagi PLKB Kelurahan Mekarwangi diharapkanuntuk membuat progam yang berkaitan dengan partisipasi suami dan peran gender dengan meningkatkan akses suami terhadap informasi, konseling dan pelayanan KB
GAMBARAN PELAKSANAAN SURVEILANS EPIDEMIOLOGI DI RUMAH SAKIT UMUM DAERAH LEUWILIANG KABUPATEN BOGOR TAHUN 2018
Authors: Akbar Putri Sholihat , Parinduri Siti Khodijah , Hidana Rachma
Published: January 2021

Rumah sakit merupakan unit pelaksana teknis Dinas Kesehatan yang bertanggung jawab menyelenggarakan pembangunan kesehatan di sebagian wilayah. Pelaksanaan surveilans epidemiologi merupakan salah satu upaya untuk mengatasi masalah penyakit menular maupun penyakit tidak menular, mengurangi kesakitan, mencegah kematian, penyembuhan penderita danmencegah terjadinya peningkatan penyakit. Tujuan penelitian ini adalah mendeskripsikan pelaksanaan surveilans epidemiologi di RSUD Leuwiliang Tahun 2018. Jenis penetian ini adalah penelitian kualitatif. Informan dalam penelitian ini adalah petugas yang melaporkan data surveilansdengan jumlah informan 4 orang. Rancangan analisa menggunakan triangulasi data, triangulasi sumber dan triangulasi metode. Hasil penelitian komponen masukan masih belum memadai dan cukup untuk mendukung kegiatan surveilans, tenaga surveilans yang masih memegang tugasrangkap, belum adanya buku pedoman. Komponen proses masih terdapat kendala terutama dalam proses pelaporan surveilans, laporan yang tidak lengkap sebanyak 75% dan ketepatan laporan yangtepat hanya 25% di tahun 2018. Komponen keluaran mengumpulkan menggunakan sofcopy.