bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimation of Adsorption Isotherm for Iron Ion on Three Different Active Carbon Types
Authors: Salem Isam A.B. , Alshoukry Abdulhameed O. , Ismael Bashaar F. , Imayof Abdulhakeem H.
Published: June 2023

The purpose of this experimental study is to estimate a suitable isotherm for the adsorption of iron ions from an aqueous solution onto three different types of active carbon. Three types of active carbons were selected, they include granular activated carbon prepared from date stone (GACD), granular active carbon prepared from charcoal (GACCH), and granular active carbon bought from the market (GACM) used for home desalination unit. The experiments were performed in a batch system at a constant temperature 20 oC and pH 7. Iron solutions of different concentrations were prepared from ferrous chloride. At equilibrium, linear forms of Langmuir isotherm, Freundlich isotherm, Timken isotherm, Dubinin-Radushkevich isotherm, and Elovich isotherm were tested with adsorption data to find the best-fit model. Freundlich and Langmuir were found to be good model for GACM, Freundlich isotherm was good model for GACCH and Langmuir isotherm best fits experimental data for GACD.
معدل الإصابة بسرطان عنق الرحم(Cervical Cancer) بمستشفى صبراتة للأورام
Authors: البب حنان الهادي
Published: June 2023

يعتبر سرطان عنق الرحم Cervical Cancer من بين الأورام الخبيثة، ومن الضروري جداً الفحص بشكل دوري وفعال للوقاية منه، ونظرا لخطورة الإصابة بسرطان عنق الرحم تمت هذه الدراسة الإحصائية لمعرفة مدى الإصابة به بين نساء من فئات عمرية مختلفة لمرضى سرطان عنق الرحم من النساء المصابات واللاتي يترددن على مستشفى صبراتة للأورام، تراوحت أعمارهن بين (18-83) خلال الفترة (2014-2017) وفق سجلات مستشفى صبراتة للأورام في الغرب الليبي، وتم تحليل البيانات باستخدام التحليل الوصفي. خلصت نتائج الدراسة إلى أن عدد الحالات المصابة بسرطان عنق الرحم بلغت 79 حالة من بين 105 حالة للعدد الكلى للمرضى، حيث أشارت النتائج إلى أن النسبة عالية للمصابات بمرض سرطان عنق الرحم المنتشر بين فئات عمرية مختلفة من النساء حيث بلغت (75%). ومن خلال هذا يوصى بالفحص الدوري المستمر واستخدام مسحة عنق الرحم في المرافق الصحية العامة والخاصة، مع حملات التوعية والتثقيف عن المرض.
Compressive Strength Improvement of Lightweight Concrete by Incorporation Waste Materials: An Experimental Investigation
Authors: Elmasri Mabrooka A. , Alaribe Ahmed Abdulqadear , Amami Mustafa M.
Published: June 2023

In the world of depletion of resources, using recycled materials is getting more and more interesting, since recycling generally reduces the need for extracting, refining, and processing raw materials. In this study, attempts to investigate the effect of two types of steel fibers (staples) on concrete compressive strength have been experimentally accomplished. The different fibers at constant fractions of 0.5%, 1%, 1.5%, and 2 % by the weight of cement are used as reinforced agents with different curing duration times of steel fibers-normal concrete samples. The results obtained by the compressive strength test showed a significant improvement in the concrete compressive strength up to 47.8 MPa could be on hand with such simple reinforcement.
TEM Image Analysis of Fracture Surfaces of P91 Steel and Comparison with Mechanical Properties
Authors: Hemer Abubkr Mohamed , Milovic L.J. , Ben Isa Muammar M. , Sharf Abdusalam M.
Published: June 2023

In order to improve the efficiency of steam boilers in modern power plants, engineers have to use contemporary materials that enable exploitation at higher parameters, primarily operating temperature and pressure, with resistance to different forms of corrosion at the same time. For that purpose, contemporary 9-12Cr martensitic steels, designated P91, P92, E911, VM12-SHC, and SHM12, were developed.

The paper analyzes experimental research on the behavior of commercial ferritic steel P91 samples. Behavior data on the heat affect zone (HAZ) of welded joints were obtained by testing smooth specimens produced by simulation of the new material welding. A survey of testing hardness and tensile properties is given and images of the fracture surfaces of the samples were processed. Image analysis with ImagePro Plus confirmed experimental testing results for the grain size measured by the circle method and a comparative relationship between the percentage of carbides, precipitates, and lamellar diameters with respect to temperature is provided.  The material that was PWHT (post-weld heat treatment) has the highest mean value of lamellar diameter, which indicates increased toughness and decreased hardness compared to BM and material without PWHT i.e (The higher lamellar diameter, the smaller material hardness).
تقييم تأثير إضافة غبار الإسمنت على بعض خصائص الإسمنت البورتلاندي
Authors: القهواجي أسامة , هرام إبراهيم , شنينة عبد الباسط , دخيل أحمد
Published: June 2023

تعتبر صناعة الإسمنت إحدى الصناعات الكبرى والاستراتيجية في ليبيا وكذلك الحال في عديد من دول العالم وتتجه الدول إلى الاهتمام بهذه الصناعة نظراً لتوجهها لإنشاء وتوفير مزيد من فرص العمل والاستثمار وإنعاش حركة الاقتصاد، ولكنها كأي صناعة أخرى لها من الجوانب ما هو سلبي خاصة على الصعيد البيئي عندما يكون هناك غازات وجُسيمات دقيقة (غبار) تطرح كنواتج عرضية من عملية التصنيع أهمها ما يطلق عليه غبار الإسمنت (Cement Dust, CD). ولغرض الاستفادة من هذه المخلفات والنواتج العرضية وتحقيق مردود بيئي واقتصادي، تناولت هذه الدراسة تقييم إمكانية الاستفادة من غبار الإسمنت (CD) من خلال إعادة تدويره وإضافته بنسب مئوية عدة (2، 4، 6، 8) % وزناً مع مادة الإسمنت البورتلاندي المنتج، وإجراء بعض الاختبارات على المكون النهائي مثل (اختبار الشك الابتدائي والشك النهائي، اختبار الضغط، وأخيراً اختبار التمدد). حيث آلت النتائج النهائية إلى أن إضافة نسبة وقدرها 6% من غبار الإسمنت (CD) إلى الإسمنت تؤدي إلى إنتاج منتج نهائي جيد يطابق المواصفات القياسية الليبية.
Effectiveness of the Presidential Secondary School Bursary (PSSB) on Education of Orphans and Vulnerable Children in Selected Sub-Counties in Nairobi City County, Kenya
Authors:   Mount Kenya University, Kenya, Sanganyi Noah M. O. , Nyandoro Kepha , Ontita Edward Gizemba , Gakunga Harrison Ng’ang’a , Onyango Eric Ater , Muhingi Wilkins Ndege i , Ndung'u Esther Mugure ,   University of Nairobi,   Directorate of Children’s Services,   Muliro University of Science and Technology, Kenya,   Pan Africa Christian University
Published: June 2023

The Presidential Secondary School Bursary (PSSB) was initiated as a complementary service to support Orphans and Vulnerable Children (OVC) in Secondary education in Kenya. However, there is limited evidence on the impact of the scheme on the enrolment, retention, and transition of OVC into higher and tertiary level education. This study examined the contribution of PSSB to the education of OVCs in Nairobi. The study anchored on the Theory of Socialist Economics of Education and Human Capital Theory. The study deployed a qualitative research design. Using purposive sampling, Nairobi County and Kasarani, Westlands, and Langata Sub-Counties were selected respectively. In each Sub-County, student beneficiaries, Principals, and Children’s Officers were the respondents. The sample size consisted of 7 students, 5 Principals, and 6 Children’s Officers selected using a purposive sampling method. In-depth interviews were conducted and data analysed using content and thematic analysis. The results show that the profile of student beneficiaries fit with the selection criteria of OVC benefitting from the scheme and that the PSSB was not adequate as most beneficiary absenteeism from schools was due to fee balances. Deserving students were left out due to non-observance of scheme procedures and guidelines. In terms of its impact, the beneficiaries’ psycho-social wellbeing was good leading to improvement in academic performance. The retention of students also improved. The study recommends an increase in the annual allocation of funds to the PSSB
Updates on the Management of Immunotherapy-Related Toxicities
Authors: Davies Marianne , McPherson Jordan , Thompson John A.
Published: June 2023

With the increased use of immune checkpoint inhibition (ICI) comes an increase in the number of patients being treated for immune-related adverse events (irAEs). At the NCCN 2023 Annual Conference, presenters discussed 3 different types of irAEs, namely immune-mediated pneumonitis, major adverse cardiac events including myocarditis and myositis/myasthenia gravis overlap syndrome, and oral toxicities including mucositis and sicca syndrome. They emphasized the importance of considering comorbidities and infectious causes when treating immune pneumonitis. In the context of cardiac events during ICI therapy, the presentation highlighted the need for early detection and vigilance in recognizing insidious, nonspecific symptoms, particularly in cases involving myocarditis with myositis/myasthenia gravis overlap syndrome. Finally, the increasing recognition of oral toxicities was discussed, in addition to the importance of timely intervention to prevent long-term morbidity.
Evaluation of Stryphnodendron polyphyllum (Mart.) pollen as antioxidant and antibacterial potential
Authors: Oliveira Albuquerque Rafael Nogueira , Martins Carlos Henrique Gomes , Souza Jonathan Henrique , Sacramento Verônica de Melo , Oliveira Dario Alves de , Melo-Júnior Afrânio Farias de , Souza Elytania Veiga , Fernandes Souza Luciano , Royo Vanessa de Andrade
Published: June 2023

El polen de Stryphnodendron polyphyllum (Mart.), típicamente conocido como barbatimão, es un problema para los apicultores con apiarios cerca de la planta, debido a toxicidad del polen para las abejas. El objetivo fue evaluar la actividad antioxidante, antibacteriana, determinar fenoles totales y taninos en el extracto etanólico. La actividad antioxidante se evaluó por método DPPH. La actividad antibacteriana se realizó por método de microdilución. Los taninos totales y fenoles se determinaron por método espectrofotométrico. Tuvimos resultados con actividad inhibitoria y bactericida para Escherichia coli, Pseudomonas aeruginosa, Streptococcus mutans, Streptococcus sobrinus, Streptococcus sanguinis, Streptococcus salivarius y Lactobacillus paracasei. Se determinó EC50 de 7.42mg/mL en la actividad antioxidante. Para compuestos fenólicos y tánicos los resultados comparados con la curva de calibración son 3,12±0,005g/100g de muestra expresados como ácido gálico y 7,3±0,03g/100g de muestra expresados como ácido tánico.

Pollen from the Stryphnodendron polyphyllum (Mart.), typically known as barbatimão, is a problem for beekeepers who have apiaries close to the plant, due to pollen toxicity for bees. The objective was to evaluate the antioxidant, antibacterial activity, determine the total phenols and tannins present in the ethanolic extract. Antioxidant activity was evaluated by the DPPH method. Antibacterial activity was performed by the microdilution method.Total tannins and phenols were determined by the spectrophotometric method. We had results with inhibitory and bactericidal activity for Escherichia coli, Pseudomonas aeruginosa, Streptococcus mutans, Streptococcus sobrinus, Streptococcus sanguinis, Streptococcus salivarius and Lactobacillus paracasei. It was determined EC50 of 7.42mg/mL in the antioxidant activity. For phenolic and tannic compounds the results compared to the calibration curve are 3.12±0.005g/100g of sample expressed as gallic acid and 7.3±0.03g/100g of sample expressed as tannic acid.
La construcción del posicionamiento lector en una narrativa digital interactiva. Una discusión a la luz de la teoría de las multiliteracidades
Authors: Gil Maitê Moraes , Pires Pereira Iris Susana , Sylla Cristina
Published: June 2023

En este artículo nos proponemos realizar una aportación a la caracterización de la multimodalidad de los textos digitales, específicamente en lo que se refiere a la comprensión de cómo funcionan las modalidades de representación en la construcción del posicionamiento lector en una narración digital interactiva. Presentamos el análisis del discurso multimodal de los significados construidos en una storyapp cuyo objetivo es promover el diálogo intercultural entre infantes. El análisis se apoya en las categorías de la Lingüística Sistémico-Funcional, la Semiótica Social y el análisis narratológico visual, se centra en la descripción de significados interpersonales representados en las modalidades verbal, visual y auditiva, y en las relaciones intermodales significativas que establecen entre sí. Los resultados revelan que la representación de significados interpersonales en el texto digital interactivo analizado, en el que destaca la promoción de sentimientos positivos de aceptación hacia la cultura representada, constituye un complejo multimodal. La discusión de la mencionada aplicación sirve, además, como ilustración de los supuestos centrales de la teoría de las multiliteracidades, evidenciando la necesidad de una nueva pedagogía en línea con las características propias de la interacción entre el lenguaje y la tecnología.
Polarización en periódicos españoles: significado y contextos de uso
Authors: Porto Requejo M. Dolores
Published: June 2023

La palabra polarización se ha popularizado en los últimos años, extendiendo su significado más allá del ámbito político a situaciones de enfrentamiento en cualquier otro contexto. Este trabajo presenta un estudio pormenorizado de la frecuencia de uso, contextos y extensión del significado en un corpus de noticias publicadas en los dos periódicos españoles más leídos, El País y El Mundo, durante el año 2021. Para ello se han combinado metodologías de la Lingüística de Corpus y del Análisis Crítico y Socio-cognitivo del Discurso, analizando tanto las frecuencias, colocaciones y construcciones sintácticas, como los contextos, los esquemas de imagen y las metáforas conceptuales que conforman su significado. Los resultados apuntan a un posible abuso del término por parte de los medios y a la confirmación de la palabra polarización como una palabra clave, que juega un papel esencial en el discurso político y mediático y que ayuda a definir el actual contexto social y cultural en España.
Pædagogers arbejde med børn og unge i fritidspædagogikken : Fritidspædagogikkens betydning for børn og unges trivsel, udvikling og livsmuligheder
Authors: Petersen Kirsten Elisa , Rose Pernelle , Damkjær-Ohlsen Sebastian , Duncan-Bendix Jennifer
Published: June 2023

Denne rapport formidler centrale resultater fra et forskningsprojekt, der har haft fokus på fritidspædagogikkens betydning for børn og unges trivsel, udvikling og livsmuligheder. Rapporten tager afsæt i et forskningsprojekt, der økonomisk er støttet af BUPL’s Forskningsfond, og som har forløbet over et år i perioden 2021-2023. I denne periode har pædagoger, ledere samt børn og unge bidraget med vigtig viden til at udforske, hvordan det fritidspædagogiske arbejde rummer muligheder for at arbejde med børn og unges trivsel, men også, hvordan det fritidspædagogiske arbejde rummer muligheder for at skabe trivsel og forebygge oplevelser af mistrivsel.
ПРИМЕНА ГИС-А У ПРОЦЕНИ ПОТЕНЦИЈАЛА СОЛАРНЕ ЕНЕРГИЈЕ У ОПШТИНИ КУРШУМЛИЈА
Authors: Tešić Dajana
Published: June 2023

Загађење животне средине и глобално загревање актуелне су теме последњих неколико деценија. Соларна енергија је најраспрострањенији обновљиви извор енергије и није ограничен у времену и простору. Стога, постоји ве- лика потреба за инсталирањем производних погона који користе обновљиве изворе енергије, а нарочито соларну енер- гију. Одабир најпогодније локације за инсталацију соларних постројења је основни предуслов за економски оправдану инвестицију. У Србији је највећи потенцијал соларне енергије у источном, јужном и југоисточном делу земље, те је за истраживано подручје изабрана општина Куршумлија. У овом раду применом географских информационих система (ГИС), извршена је идентификација погодних локација за примену соларне енергије у општини Куршумлија. За ана- лизу потенцијала соларне енергије у општини Куршумлија изабрано је 5 фактора: соларна радијација, нагиб терена, начин коришћења земљишта, експозиција терена и удаљеност од путева. У анализи фактора је коришћена Analytic Hiearchy Process (AHP) метода како би се одредила важност сваког фактора. Након тога је извршено преклапање слоје- ва помоћу алата Weighted Overlay Method (WOM) у ArcGIS Pro софтверу. Резултати ове анализе указују на то да је уку- пно 19 % истраживаног подручја изузетно погодно за изградњу соларних електрана, 46 % површине спада у умерено погодна подручја за изградњу, док је 20.4 % подручја маргинално погодно. Преосталих 14.6 % подручја су заштићена подручја која су искључена из анализе. Резултати овог рада могу користити соларним комуналним предузећима, енер- гетским компанијама и креаторима политике да одаберу потенцијална места за изградњу соларних електрана.
CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance
Authors: Li Yu , Guaman Tipan Pablo , Selden Hilary J , Srinivasan Jayashree , Hale Laura P , Ehrlich Lauren IR
Published: June 2023

Central tolerance ensures autoreactive T cells are eliminated or diverted to the regulatory T cell lineage, thus preventing autoimmunity. To undergo central tolerance, thymocytes must enter the medulla to test their T-cell receptors (TCRs) for autoreactivity against the diverse self-antigens displayed by antigen-presenting cells (APCs). While CCR7 is known to promote thymocyte medullary entry and negative selection, our previous studies implicate CCR4 in these processes, raising the question of whether CCR4 and CCR7 play distinct or redundant roles in central tolerance. Here, synchronized positive selection assays, two-photon time-lapse microscopy, and quantification of TCR-signaled apoptotic thymocytes, demonstrate that CCR4 and CCR7 promote medullary accumulation and central tolerance of distinct post-positive selection thymocyte subsets in mice. CCR4 is upregulated within hours of positive selection signaling and promotes medullary entry and clonal deletion of immature post-positive selection thymocytes. In contrast, CCR7 is expressed several days later and is required for medullary localization and negative selection of mature thymocytes. In addition, CCR4 and CCR7 differentially enforce self-tolerance, with CCR4 enforcing tolerance to self-antigens presented by activated APCs, which express CCR4 ligands. Our findings show that CCR7 expression is not synonymous with medullary localization and support a revised model of central tolerance in which CCR4 and CCR7 promote early and late stages of negative selection, respectively, via interactions with distinct APC subsets.
Comprehensive characterization of tumor microenvironment in colorectal cancer via molecular analysis
Authors: Wu Xiangkun , Yan Hong , Qiu Mingxing , Qu Xiaoping , Wang Jing , Xu Shaowan , Zheng Yiran , Ge Minghui , Yan Linlin , Liang Li
Published: June 2023

Colorectal cancer (CRC) remains a challenging and deadly disease with high tumor microenvironment (TME) heterogeneity. Using an integrative multi-omics analysis and artificial intelligence-enabled spatial analysis of whole-slide images, we performed a comprehensive characterization of TME in colorectal cancer (CCCRC). CRC samples were classified into four CCCRC subtypes with distinct TME features, namely, C1 as the proliferative subtype with low immunogenicity; C2 as the immunosuppressed subtype with the terminally exhausted immune characteristics; C3 as the immune-excluded subtype with the distinct upregulation of stromal components and a lack of T cell infiltration in the tumor core; and C4 as the immunomodulatory subtype with the remarkable upregulation of anti-tumor immune components. The four CCCRC subtypes had distinct histopathologic and molecular characteristics, therapeutic efficacy, and prognosis. We found that the C1 subtype may be suitable for chemotherapy and cetuximab, the C2 subtype may benefit from a combination of chemotherapy and bevacizumab, the C3 subtype has increased sensitivity to the WNT pathway inhibitor WIKI4, and the C4 subtype is a potential candidate for immune checkpoint blockade treatment. Importantly, we established a simple gene classifier for accurate identification of each CCCRC subtype. Collectively our integrative analysis ultimately established a holistic framework to thoroughly dissect the TME of CRC, and the CCCRC classification system with high biological interpretability may contribute to biomarker discovery and future clinical trial design.
De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness
Authors: Koh Jaemoon , Woo Yeon Duk , Yoo Hyun Jung , Choi Jun-Pyo , Kim Sae Hoon , Chang Yoon-Seok , Jung Kyeong Cheon , Kim Ji Hyung , Jeon Yoon Kyung , Kim Hye Young , Chung Doo Hyun
Published: June 2023

Invariant natural-killer T (iNKT) cells play pathogenic roles in allergic asthma in murine models and possibly also humans. While many studies show that the development and functions of innate and adaptive immune cells depend on their metabolic state, the evidence for this in iNKT cells is very limited. It is also not clear whether such metabolic regulation of iNKT cells could participate in their pathogenic activities in asthma. Here, we showed that acetyl-coA-carboxylase 1 (ACC1)-mediated de novo fatty-acid synthesis is required for the survival of iNKT cells and their deleterious functions in allergic asthma. ACC1, which is a key fatty-acid synthesis enzyme, was highly expressed by lung iNKT cells from WT mice that were developing asthma. Cd4-Cre::Acc1fl/fl mice failed to develop OVA-induced and HDM-induced asthma. Moreover, iNKT cell-deficient mice that were reconstituted with ACC1-deficient iNKT cells failed to develop asthma, unlike when WT iNKT cells were transferred. ACC1 deficiency in iNKT cells associated with reduced expression of fatty acid-binding proteins (FABPs) and peroxisome proliferator-activated receptor (PPAR)γ, but increased glycolytic capacity that promoted iNKT-cell death. Furthermore, circulating iNKT cells from allergic-asthma patients expressed higher ACC1 and PPARG levels than the corresponding cells from non-allergic-asthma patients and healthy individuals. Thus, de novo fatty-acid synthesis prevents iNKT-cell death via an ACC1-FABP-PPARγ axis, which contributes to their homeostasis and their pathogenic roles in allergic asthma.
Eradication of Helicobacter pylori Infection Using 7-day PCR-based Tailored Therapy
Authors: Kim Youngwoo , Kang Heejun , Moon Sang-Gon , Kim Bohyoung , Lee Hyeyeon , Lim Chul-Hyun , Oh Jung-Hwan
Published: June 2023

Background/Aims: Standard triple therapy (STT; proton pump inhibitor [PPI]+clarithromycin+amoxicillin) used for Helicobacter pylori (H. pylori) eradication has shown low treatment success rates in recent years, which is most likely attributable to increased clarithromycin resistance. In this study, we compared treatment success rates of tailored therapy (TT) using real-time polymerase chain reaction (RT-PCR) and empirical STT.Methods: This retrospective study included 650 patients with H. pylori infection, who visited Eunpyeong St. Mary’s Hospital in Korea; 343 patients received TT based on RT-PCR assays, and 307 patients received STT. Eradication success was defined as a negative 13C-urea breath test result 4~8 weeks after treatment completion. Patients who failed first-line therapy and those with clarithromycin resistance received bismuth-containing quadruple therapy (BQT; PPI+bismuth+metronidazole+tetracycline).Results: Intention-to-treat analysis showed that H. pylori eradication rates were higher in patients who received RT-PCR–based TT than in those who were treated using empirical STT (80.5% [190/236] vs. 70.4% [216/307], P=0.069). Per-protocol (PP) analysis showed similar results (84.4% [190/225] vs. 74.7% [216/289], P=0.007). PP analysis showed that 7-day TT treatment was associated with a higher eradication rate than that observed with 10- to 14-day STT (85.2% [178/209] vs. 73.8% [59/80], P=0.029). The clarithromycin resistance rate was 27.9% (87/312). The eradication success rate was 89.2% (74/83) in patients with clarithromycin resistance, who received BQT as first-line therapy.Conclusions: The treatment success rate was higher in patients who received 7-day RT-PCR–based TT than in those who were administered 10- to 14-day empirical treatment.
Planejamento, programação e controle da produção na indústria
Authors: Nogueira Nelrian de Brito , Roberto José Carlos Alves , Souto Sistina Pereira , De Lima Orlem Pinheiro , De Araújo Paulo César Diniz
Published: June 2023

O PPCP é uma ferramenta utilizada para acompanhar todas as atividades necessárias para que uma empresa transforme os insumos em produtos, atendendo aos pedidos realizados pelos clientes. O planejamento e controle da produção é uma área central na administração das empresas manufatureiras. Sobretudo quando a produção se efetua por lotes ou em pequenas séries, seja para encomendas, seja para estoque, a programação tem que atender a objetivos conflitantes, devendo entregar todas as ordens de produção no prazo prometido, ao mesmo tempo que mantém as máquinas e os homens ocupados a plena capacidade e minimiza os níveis de estoques de materiais e produtos em fase de processamento.  O sistema de produção enxuta foi criado no Japão pela empresa Toyota a qual inseriu em sua metodologia a ergonomia. O sucesso do toyotismo se baseia na predominância da ergonomia em seu sistema de produção que nada mais é do que o bem-estar dos seus empregados que consequentemente trabalham mais motivados gerando mais produtividade e eficiência em seus produtos produzidos demonstrando que a ergonomia melhora a condição de trabalho humano e com isso aumenta a produtividade. Os modelos de produção taylorista/fordista não são tão produtivos quanto o modelo de produção enxuta, pois possuem perdas ergonômicas acarretadas pelo seu sistema de produção baseado nos ideais tayloristas como, por exemplo, os trabalhos repetitivos e monotonos que podem prejudicar a saúde dos trabalhadores e a sua produtividade. No modelo fordista, o pioneiro da na produção automobilística, era um modelo de produção em massa onde os funcionários sofriam maus tratos e trabalho quase escravo. Nesses sistemas de produção a saúde dos funcionários era esquecida e a importância era somente a corrida pela produtividade.
B Lymphoblastic Lymphoma of Thigh: A Case of an Unusual Location
Authors: Nair Pallavi , Sugeeth MT , Jayasudha AV
Published: June 2023

B-Lymphoblastic Lymphoma (B-LBL) is a malignancy of immature B lymphoid cells. They have a low propensity for bone marrow involvement. They typically present as generalised lymphadenopathy, bone lesions, mediastinal or skin lesions. They present with more skin and soft tissue involvement than acute lymphatic leukaemias. They are treated with systemic chemotherapy similar to their leukaemic counterparts. They have a favourable prognosis with a survival of 90%, although it worsens with age. Here, we present the case of a 23-year-old gentleman who was evaluated for a swelling in the posterior aspect of right thigh clinically resembling a sarcoma. Imaging studies showed a lesion in the posterior compartment of right thigh which showed contrast enhancement and hyperintensity in T2 images. Pelvic and inguinal node was enlarged. Ultrasound guided biopsy from the lymph node was suggestive of B-LBL. There was no bone marrow involvement. He was treated according to Berlin-Frankfurt-Munster (BFM) 95 protocol and attained remission post induction. He completed induction, consolidation and reinduction and is currently on maintenance treatment.
The Role of Teaching and Learning Theories in Preparing Student Teachers to Teach Mathematics and Enhancing Learners' Readiness to Learn: A Case Study of Bia Lamplighter College of Education in Ghana
Authors: Adams Alfred Kofi , Asemnor Felix
Published: June 2023

Aim: The study aimed to investigate the role of teaching and learning theories in preparing teachers to teach mathematics and in enhancing students' readiness to learn. Specifically, the study explored the application of constructivist and pedagogical content knowledge (PCK) theories in a teacher preparation program and in classroom instruction.

Study Design: The study employed a case study design and involved pre-service teachers and their students in a mathematics classroom. Data was collected through interviews, observations, and document analysis.

Methodology: The study employed a case study design to investigate the application of constructivist and PCK theories in a teacher preparation program and in classroom instruction. The study involved pre-service teachers and their students in a mathematics classroom. A purposive sampling technique was used to select ten (10) final year student teachers who can provide rich and detailed information about their readiness to teach and learn mathematics, as well as their understanding and application of learning and teaching theories. Also, one hundred (100) students were purposively selected for the study. Data was collected through interviews, observations, and document analysis and was analyzed using thematic analysis.

Results: The findings revealed that pre-service teachers who were exposed to constructivist and PCK-based instruction in their teacher preparation program were better equipped to design and deliver mathematics lessons that promote active learning and deep understanding of mathematical concepts. Moreover, students who were taught in a constructivist and PCK-based learning environment demonstrated higher levels of readiness to learn mathematics. The study provides insights into the effectiveness of using learning and teaching theories in mathematics education and highlights the importance of incorporating these theories in teacher preparation programs.

Conclusions: Based on the findings and analysis of this study, it can be concluded that the application of constructivist and PCK-based instruction in mathematics teacher preparation programs has a positive impact on pre-service teachers' readiness to teach mathematics.

To successfully incorporate constructivist and PCK-based instruction in mathematics teacher preparation programs, it is important to provide adequate support and training for instructors and to engage in ongoing evaluation and refinement of these programs. By doing so, we can help to ensure that future mathematics teachers are prepared to effectively facilitate learning and promote mathematical understanding in their classrooms.
gr-connectedness in Topological Spaces
Authors: Vithyasangaran K. , Sathaananthan S. , Sriranganesan J.
Published: June 2023

We discuss about gr -connectedness and different properties of it, such as remarks, examples and theorems.
Exact Solutions for Some Singular Linear Ordinary Differential Equations of High Orders via NB1 Polynomials
Authors: Assabaai Mobarek A. , Kherd Ahmed
Published: June 2023

In this study, we numerically solve the singular linear ordinary differential equations (SLODEs) of higher order using the collocation method based on the NB1 polynomial. An operational matrix form of the given ordinary differential equations (ODEs), the relations of various solutions and the derivatives are obtained from NB1 polynomials. The proposed method reduces the given problem to a linear algebraic equation system, which removes the singularity of ordinary differential equations. The inverse matrix method is used to solve the resulting system to obtain the coefficients of NB1 polynomials. The obtained exact solutions to different problems of high orders show the reliability and accuracy of the presented method.
Biological Control of Early Blight of Tomato (Solanum lycopersicum L.) by the Use of Pseudomonas fluorescens (Flugge and Migula) under Field Condition
Authors: Dobariya K. G. , Pandya J. R. , Pandya R. P. , Joshi S. H.
Published: June 2023

Tomato is the second most important vegetable crop. It is widely grown on all over the world. Diseases are the major constraint in economic crop production as they inflict heavy loss in tomato. Among the various fungal diseases, early blight was reported severe as it causes heavy damage to the crop. The main aim of this study is to explore the potentiality of native and most efficient isolate of P. fluorescens as biocontrol agent. A total 30 Pseudomonas fluorescens isolates were isolated from soil samples of different villages of Navsari district by serial dilution method on King’s B medium. The isolates were purified by observing under UV light. A field experiment was conducted for evaluation of P. fluorescens against diseases of tomato. Among the different treatments of P. fluorescens, treatment T8 i.e. combined use of all treatments recorded with minimum per cent disease intensity (37.78%) against early blight disease and maximum per cent disease intensity (69.33%) was recorded in the control (T9, water spray).
A Vision toward Regenerative Organic Agriculture to Sustain Climate Change and Combat Global Warming
Authors: Banerjee Shubhanjali , Verma Shivani , Regmi Rabin , Kaushal Shilpa
Published: June 2023

Regenerative Agriculture (RA) could be considered as a part of acquiring and maintaining sustainability. RA depends on Sustainable Development Goals (SDGs) for functioning and enhancements related to all kinds of natural resources. The existence of Air and Water Quality Acts and capitalizing on the benefits of the soil-water-air nexus depends on implementing a "Soil Quality Act". The rate of the annual increase in soil C is only transient, even if soil organic matter rises as a result of better management. The rate of carbon accumulation slows as a new equilibrium is reached. Under cultivation at a lower level than a natural vegetative cover. Most intergovernmental panel on climate change (Intergovernmental Panel on Climate Change) scenarios incorporate net-negative emission technologies to maintain global warming to a maximum of 1.5°C, over pre-industrial levels given present trends in greenhouse gas emissions. Vermicompost has proven to be a "miracle plant growth enhancer". It promotes 30-40% over chemical and organic fertilizers and protects plants from pests and diseases. Studies have shown that composting earthworm waste significantly reduces total greenhouse gas emissions in the form of CO2 equivalents, especially nitrous oxide (N2O), which is 296-310 times greenhouse gas than CO2. The study showed that the vermicomposting system emitted an average of 463 CO2-e/m2/h. This is significantly less than the landfill emissions of 3640 CO2-e /m2 /h. Vermicomposting released at least N2O – 1.17 mg/m2/h compared to aerobic and anaerobic compost (1.48 and 1.59 mg/m2/h, respectively). Therefore, earthworms can play a good role in greenhouse gas reduction and mitigation strategies in  municipal solid waste disposal. Organic systems show a nearly 30% increase in soil carbon over 27 years.
An Economic Analysis of Climate Change in Dry Lands of Maduri District, Tamil Nadu, India
Authors: Amarnath J. S. , Yogitha P. , Sivasankari B.
Published: June 2023

The study was conducted in dry lands of Madurai district with a sample size of 150 to study the vulnerability, resilience and adaptation strategies to climate change and also to assess the sustainability of dry land farming and livelihood security of dry land farmers. The results revealed that Thirumangalam block was highly vulnerable to climate change with the index value of 0.689. In ecological sustainability, sorghum was more sustainable. Economic viability analyses showed that cotton was more sustainable The dependency on local inputs was higher for both cotton and sorghum with comparative higher usage of local inputs, such as labour, seed and Farm Yard Manure. Migration percentage was relatively high in dry land agro ecosystem due to low employment generation in this system. Thus, the resilience analysis showed that the migration has to be checked, savings has to be enhanced. Farm Yard Manure was the most important green technology adopted by the farmers with a proportion of 50.00 per cent.  The livelihood security analyses that farmers in dry land system were much secure in habitat and social network security. Farmers’ perceived decline in yield was the most important impact of climate change and labour shortage was the most important constraint in adoption of climate resilient technologies. Policy implication suggested include suitable technological interventions should be given to sorghum farmers to make the crop more economically viable. Government should initiate agricultural development and welfare programmes for dryland farmers in the region.
Performance of Pearl Millet and Pulses Based Intercropping System under Rainfed Condition
Authors: Victor V. Preethi , Sharmili K. , Kumar P. Dinesh , Minithra R. , Balaganesh B.
Published: June 2023

A field experiment was conducted during rabi season of 2022 at Karunya Institute of Technology and Sciences, Coimbatore to study the performance of different pearl millet-based intercropping with legumes under rainfed condition. Greengram (Vigna radiata), cowpea (Vigna unguiculata) and redgram (Cajanus Cajan) were sown as intercrops in replacement series of 4:1 and 6:1 row ratio. The result of the study indicated that intercropping of blackgram and redgram with pearl millet in 4:1 gave higher total grain yield (25503.0 kg/ha) and stover yield (4927.1 kg/ha) compared to the sole cropping of pearl millet under rainfed condition. Other intercropping indices like grain equivalent yield, land equivalent ratio, relative crowding coefficient, competition index and income equivalent ratio were calculated. Intercropping system of pearl millet + blackgram (4:1) recorded the higher net returns (Rs. 81,621/ha) and B:C ratio (2.42).
Physicochemical and Organoleptic Characterization of Flavoured Pineapple Candy (Ananas comosus L.)
Authors: Vaiphei Ch Muanlem , Joseph Annjoe V.
Published: June 2023

An experiment was conducted at the Post Harvest Technology, Department of Horticulture, SHUATS, Prayagraj (Uttar Pradesh) during the year 2022-2023. The pineapple (Ananas comosus L.) is a popular tropical fruit in India. It is well-known for its nutritional and therapeutic properties, but it is not an easy food to consume on its own. It has a lot of potential in processed forms like candy. Attempts are being made to create products that are not only nutritionally delicious but also consumer-acceptable. The medicinal, nutritional, and organoleptic quality of pineapple candy can be improved by mixing in different syrups such as mint syrup, rose syrup, tulsi syrup, ginger syrup, and cardamom syrup. The study followed a completely randomised design with three replications. The pineapple candy samples were examined for physicochemical changes after preparation and sensory evaluation was performed on a panel of 7 experts using a 9-point hedonic scale. These candies were kept at room temperature for around 90 days. The storage experiments demonstrated that total soluble solids and pH gradually increase till the end of the experiment, whereas titratable acidity and ascorbic acid decrease in decreasing order. Based on the organoleptic test results, treatment T3 (Pineapple + Sugar syrup @ 60% + Rose extract @ 10%) was determined to be the best-flavoured pineapple candy.
Characterization and Functional Properties of Lactic Acid Bacteria Isolated from Fermented Maize Dough Used for the Preparation of Doklu
Authors: Assohoun Wilson L. A. , Assohoun-Djeni Christelle M. N. , Aka-Gbezo Solange , Djeni Théodore N. , Dje Marcellin K.
Published: June 2023

Lactic acid bacteria (LAB) has long been safely applied in the production of fermented foods and beverages. These bacteria are important for their contribution to food quality and also for their undeniable effects on health. In Africa, despite the abundance of isolated food sources and the diversity of identified microorganisms, the market for probiotics and functional foods based on selected local strains is almost non-existent. This paper aims to determine some technological properties of LAB isolates from fermented maize dough used for doklu production for potential application in food and probiotic products. A total of 25 LAB strains isolated from maize dough fermentation processes during doklu production were identified by 16S rDNA gene sequencing. Technological studies such as growth and acidification kinetics, diacetyl production, hydrogen peroxide production, and proteolytic activity were carried out. Their survival and growth under unfavorable conditions of temperature, salt concentration and pH were also analyzed. The isolates were identified as Pediococcus acidilactici (56%), Lactobacillus fermentum (24%), Pediococcus pentosaceus (12%) and Lactobacillus plantarum (8%). The technological properties of the LAB strains showed that 10 of them rapidly acidify the medium with pH variation (ΔpH) greater than 1 after 6 hours of fermentation. Good production of diacetyl and hydrogen peroxide, as well as good proteolytic activity, were obtained for several strains. Pediococcus acidilactici S15, S55, S56; Lactobacillus plantarum S32, S121 and Lactobacillus fermentum S44 showed the best technological properties. However, only 5 of them obtained good resistance following the various survival and growth under unfavorable conditions of temperature, salt concentration, and pH. This work has therefore demonstrated that the lactic acid bacteria involved in the natural fermentation of maize dough have interesting properties for various applications whether in the processing of food products as well as in the development of probiotic products.
Compounded Biological Soil Conditioner for Soybean Crop Production at Brazil
Authors: Bacilieri Fernando S. , Nichio Bruno , Lemes Ernane M. , Gurski Bruno C.
Published: June 2023

Aim: To evaluate the agronomic efficiency of Bacillus-based soil conditioner on soybean crop development and productivity in different cropping areas.

Study Design: Randomized complete block design with six treatments and eight replications.

Place and Duration of Study: Municipalities of Uberlândia, Paracatú, Araxá and Guarda Mor, all in Minas Gerais State, Brazil, during the 2019/20 season.

Methodology: The treatments consisted of untreated control, 300 kg ha-1 of mineral fertilizer, 2.0, 2.5, 3.0, 3.5 L ton-1 of Bacillus-based soil conditioner applied to mineral fertilizer (BSC2.0; BSC2.5; BSC3.0; BSC3.5). Leaf and grain P and K concentration, soybean yield components (grains per pod, pods per plant, weight of a thousand grains) and grain yield were evaluated. Data were subject to ANOVA at P = 0.10. Treatments means were separated using the Duncan test at a 0.10 level of significance. 

Results: The biological soil conditioner (BSC) had a statistically superior response than mineral fertilizer in all evaluated doses. In Uberlândia, the BSC2.0 treatment was more efficient in increasing the foliar P concentration in soybean. In Araxá, BSC3.0 provided greater grain yield, as it increased the number of pods per plant and soybean yield. BSC3.5 obtained higher grain yield in Paracatú and Guarda Mor. The average soybean yield achieved in all areas was higher than that obtained in the state of Minas Gerais.

Conclusion: This study revealed that using Bacillus-based soil conditioner on soybean crops is a valuable strategy to increase the soil activity, development and crop yield.
DEVELOPING A SUSTAINABLE TOURISM VILLAGE MODEL: AN EXPLORATORY STUDY
Authors: Suharti Lieli , Sirine Hani , Martono Samuel
Published: June 2023

Studies on sustainable tourism villages (STV) development highlighted the role of community-based tourism (CBT) and social entrepreneurship (SE). Previous studies mostly focused on com­mu­ni­ty and social entrepreneurship but neglected tourism management, which became the research gap of this study. The aim of this study was to investigate the contributions of CBT, SE, and tourism management in sustaining a tourism village. This study used a qualitative method, so the data were collected through focus group discussions and in-depth interviews with key players of Kaki Langit Mangunan Tourism Village, Yogyakarta. The results showed that the involvement and integration of CBT and SE were crucial in achieving STV. Finally, STV also required professionalism in ma­na­gement.
The Stories We Tell Ourselves
Authors: Chammas Danielle
Published: June 2023

In this narrative medicine essay, a palliative care physician discusses how the simple choice of words and the act of listening can redirect a patient’s despair to hope in helping them rewrite their narratives.
Effect of a Continuous Bedside Pressure Mapping System for Reducing Interface Pressures
Authors: Ho Chester , Ocampo Wrechelle , Southern Danielle A. , Sola Darlene , Baylis Barry , Conly John M. , Hogan David B. , Kaufman Jaime , Stelfox Henry Thomas , Ghali William A.
Published: June 2023

Importance

Continuous bedside pressure mapping (CBPM) technology can assist in detecting skin areas with excessive interface pressure and inform efficient patient repositioning to prevent the development of pressure injuries (PI).

Objective

To evaluate the efficacy of CBPM technology in reducing interface pressure and the incidence of PIs.

Design, Setting, and Participants

This parallel, 2-group randomized clinical trial was performed at a tertiary acute care center. The study started to enroll participants in December 2014 and was completed in May 2018. Participants included adults partially or completely dependent for bed mobility. Statistical analysis was performed from September 2018 to December 2022.

Intervention

Nursing staff using visual feedback from CBPM technology for 72 hours.

Main Outcomes and Measures

Absolute number of sensing points with pressure readings greater than 40 mm Hg, mean interface pressure across all sensing points under a patient’s body, proportion of participants who had pressure readings greater than 40 mm Hg, and pressure-related skin and soft tissue changes.

Results

There were 678 patients recruited. After attrition, 260 allocated to the control group (151 [58.1%] male; mean [SD] age, 61.9 [18.5] years) and 247 in the intervention group (147 [59.5%] male; mean [SD] age, 63.6 [18.1] years) were included in analyses. The absolute number of sensing points with pressures greater than 40 mm Hg were 11 033 in the control group vs 9314 in the intervention group (P = .16). The mean (SD) interface pressure was 6.80 (1.63) mm Hg in the control group vs 6.62 (1.51) mm Hg in the intervention group (P = .18). The proportion of participants who had pressure readings greater than 40 mm Hg was 99.6% in both the control and intervention groups.

Conclusions and Relevance

In this randomized clinical trial to evaluate the efficacy of CBPM technology in the reduction of interface pressure and the incidence of PIs in a tertiary acute care center, no statistically significant benefit was seen for any of the primary outcomes. These results suggest that longer duration of monitoring and adequately powered studies where CBPM feedback is integrated into a multifaceted intervention to prevent PI are needed.

Trial Registration

ClinicalTrials.gov Identifier: NCT02325388