bluuebunny/crossref_metadata_2025 huggingface dataset:
Helenistik ve Roma Dönemlerinde Ezoterik Bir Yahudi Topluluk
Authors: AÇIL Okan
Published: December 2022

MÖ II. yüzyıl ila MS I. yüzyıl aralığında Yahudiye’de yaşamış olan Esseniler, modern araştırmacılar tarafından Antik döneme ait bir Yahudi mezhebi olarak kabul edilmektedir. Türkçe literatürde fazla müstakil çalışmaya konu olmamış bu grubu incelemeyi amaçladığımız çalışmada birincil kaynaklardan istifade etmeye azami ölçüde gayret gösterilmiştir. Bunun yanında bir takım ikincil kaynaklardan da faydalanılmıştır. Çalışmada Esseniliğin tanımı, coğrafyası, inanç ve yaşam biçimleri ile teşkilat ve toplumsal yapıları incelenmeye çalışılmıştır. Sonuç olarak şunlar söylenebilir; Esseniler, tek bir cemaat değildir. Aksine, Ölü Deniz’in batı kıyıları yakınlarında bulunan ana cemaatin dışında Yahudiye’de dağınık halde yaşayan başka cemaatlerden oluşmaktadır. Esseni nüfusu MS I. yüzyılda yaklaşık dört bin kişi kadardır. Esseniler, inanç ve yaşayış bakımından çeşitli sebeplerin etkisiyle II. Tapınak Dönemi Yahudiliğinden oldukça farklılaşmıştır. Esseniliğe ait cemaatler ve üyeler içerisinde idari ve mali alanlar başta olmak üzere teşkilatlanmaya gidildiğine dair emareler bulunmaktadır. Esseniliğe aday olanların topluluk kriterleri doğrultusunda çeşitli aşamalardan oluşan bir elemeye tabi tutulması ile eğitim ve bilgi aktarım metotları inisiyasyona başvurulduğu ihtimalini akla getirmektedir. Var olduğu düşünülen inisiyasyon, Essenilere ait derin bilgi ve sırların dışa kapalılığı ve bu bilgilere sadece ehil görülen kimselerin erişebilmesi, katı gizlilik ilkesi ile derin bilgilerin tahrif edilmeden yeni üyelere aktarılması ise Essenileri ezoterik bir topluluk olarak değerlendirilmesinin temelini oluşturmaktadır.
Balance de la legislación de urgencia emitida en el marco de la emergencia sanitaria por la Covid 19 en el Perú y propuesta de reforma
Authors: Ponce Rivera Carlos A. , Hidalgo Salas Darwin E.
Published: December 2022

La pandemia producida por el virus del SARS COV 2, es el episodio más importante a nivel mundial durante los últimos años por cuanto además de sus efectos sanitarios ha cambiado aspectos muy sensibles de la vida social y económica de las sociedades en todo el mundo. La necesidad de enfrentar los efectos de la enfermedad ha obligado a los Estados a recurrir a la emisión de normas de urgencia dictadas en el marco de prerrogativas excepcionales establecidas en la Constitución Política pero que no están diseñadas para enfrentar eventos de la magnitud y características de una emergencia sanitaria de proporciones mundiales. Por esa razón es necesario evaluar la pertinencia de dicha legislación en un contexto en donde la posibilidad de un nuevo episodio similar al vivido desde el 2020 no es un cálculo ajeno a la realidad, y en donde fenómenos como el calentamiento global, la contaminación y la sobre explotación de recursos naturales hacen pensar en la posibilidad de la presentación de emergencias sanitarias que con mayor recurrencia afecten a las sociedades. En esa línea de pensamiento, el siguiente artículo pretende aportar en ese análisis a partir de la descripción de las acciones que el Estado peruano implementó durante los años 2020 y 2021 para concluir en la necesidad de una reforma constitucional que permita al Poder Ejecutivo enfrentar eventos como los vividos en un marco de legalidad y respecto al equilibrio de poderes.
La figura del colaborador eficaz como componente del Derecho Penal Premial
Authors: Momblanc Liuver Camilo , Sosa Zúñigas Alianna
Published: December 2022

En el artículo se presenta una sistematización de los fundamentos generales que caracterizan el Derecho Penal Premial, la evolución histórica de esta modalidad del Derecho Penal moderno y los aspectos fundamentales que se han esgrimido en relación a ello. Igualmente, contiene las nociones elementales en torno a la figura del colaborador eficaz, que sustentan la incorporación de esta nueva institución en las prácticas legales modernas. Es por ello que constituyó el objetivo principal sistematizar, desde una perspectiva teórica, exegética y jurídico-comparada, los elementos que sustentan la colaboración eficaz como expresión del Derecho Penal Premial. Se utilizaron como métodos el histórico-lógico, análisis-síntesis, Derecho comparado e inducción-deducción.
Management of patients with acute radiation dermatitis. Current trends and clinical examples
Authors: Balaeva D. A. , Romanov D. S.
Published: December 2022

Nowadays radiotherapy is one of the main methods of cancer treatment. According to the WHO, more than 50% of patients with diagnosed malignancies need radiation therapy. However, there are a number of side effects of the latter, which are as much the task of the radiotherapist as the actual treatment of the tumor. Skin reactions are one of the most common side effects of radiation therapy, affecting up to 85-95% of patients. Radiation dermatitis is a unique pathology compared to other forms of skin damage, such as traumatic, because the radiation spreads from the epidermis to the deep tissue layers consistently. Such skin reactions can cause some discomfort in cancer patients and even real problems, including interruptions in treatment, decreased aesthetic appeal and decreased quality of life. Recent technological advances and new radiodermatitis treatment regimens represent an opportunity to alleviate the side effects of radiation therapy. Despite a variety of techniques for conservative treatment of radiation dermatitis, the most severe cases may require complex surgical reconstruction of the damaged skin, which is why correction and prevention of skin reactions is a priority in patient care. Despite the large number of trials in this area, there are few qualitative comparative studies that can provide a clear picture of the efficacy of individual radiodermatitis-relieving agents. This literature review reviews the current agents used to treat and prevent acute radiation dermatitis, as well as their mechanisms of action. Three electronic databases, including PubMed, Cochrane, and Embase, were used to find information for the systematic review.
First results of durvalumab after chemoradiotherapy in locally advanced non-small-cell lung cancer in Russia
Authors: Yudin D. I. , Laktionov K. K. , Moiseenko F. V. , Ponomarenko D. M. , Chekh E. A. , Chubenko V. A. , Levchenko N. V. , Kozlov V. V. , Stepanova E. О. , Sarantseva K. A. , Denisova E. S. , Ardzinba M. S. , Yukalchuk D. Yu.
Published: December 2022

Introduction. The addition of durvalumab after chemoradiation therapy in unresectable stage III non-small-cell lung cancer (NSLC) is a new standard of care.

Aim. Study the features and outcomes of durvalumab maintenance treatment after chemoradiotherapy in patients with unresectable stage III NSCLC in the real-world clinical practice in Russia.

Materials and methods. 50 patients with unresectable III stage NSCLC after concurrent or sequential chemoradiotherapy (CRT) were enrolled in this observational retrospective study. Median follow up time at primary analysis was 12.4 months.

Results. A mean age of the patients in the study was 61.2 years (58.4-64.1; 95% CI). Most of the patients had received sequential CRT (76%, n = 38). Median time of durvalumab start from the end of CRT varied from 22 to 50 days (overall - 35 days). Estimated median PFS and OS were 10.86 months (7.78-14.01, 95% CI) and 26 months (20.19-31.81, 95% CI), respectively. There was a trend toward increased PFS in patients with smoking history: 12 months (9.79-14.2; 95% CI) versus 4,9 months (0.0-12.47; 95% CI), p = 0.2. Half of the patients without smoking history (5/10) had targetable mutations (EGFR ex 19, ALK, ROS1, cMET). Most common reported adverse events of special interest were pneumonitis grade 1-2 (36%, n = 18), leading permanent treatment discontinuation to in 6% of patients (n = 3). There were no reported cases of grade 3-4 adverse events.

Conclusions. Real-world characteristic of patients in our study were different from PACIFIC trial. Sequential CRT is the most frequent treatment option in locally advanced unresectable NSCLC in Russia. Estimated PFS was shorter than in PACIFIC, but there were less cases of pneumonitis.
Optimal choice of drug antitumor treatment in patients with Fibrolamellar liver carcinoma
Authors: Antonova E. Yu. , Moroz E. A. , Dzhanyan I. A. , Volkov A. Yu. , Laktionov K. K. , Breder V. V.
Published: December 2022

Introduction. Fibrolamellar hepatocellular carcinoma (FlC) is a rare subtype of hepatocellular carcinoma (HCC). Drug antitumor treatment of FlC has not been studied sufficiently due to the rarity of the pathology and requires further research to choose an effective treatment.

Aim. The choice of effective drug antitumor treatment in patients with fibrolamellar liver carcinoma.

Materials and methods. The retrospective study included 31 patients with FlC who received drug antitumor therapy at the N.N. Blokhin National Research Center of Oncology of the Ministry of Health of the Russian Federation in the period from 2005 to 2020. The patients were divided into comparison groups: “targeted therapy” (mainly sorafenib), “chemotherapy” (mainly gemcitabine + cisplatin). A comparative intergroup analysis of the effectiveness of drug antitumor treatment in the 1st and 2nd lines of therapy was carried out. Adjuvant chemotherapy was evaluated for time without progression. The correlation of the number of treatment lines in the anamnesis with the prognosis of the disease was also evaluated.

Results. Analysis of the effect of adjuvant therapy on relapse-free survival did not prove significant differences between the comparison groups (p = 0.112; log-rank test). Therapy with multikinase inhibitors (mainly sorafenib) allows to achieve a better time without progression compared to chemotherapy (mainly gemcitabine + cisplatin / oxaliplatin) (p = 0.000; log-rank test) in patients in the 1st line of FlC treatment. OS did not significantly differ between the groups (p = 0.417; log-rank test). In line 2, time without progression in patients receiving targeted therapy (p = 0.042; log-rank test) is higher compared to patients receiving chemotherapy in line 2. A longer duration of OV was recorded in the groups of patients who underwent 2 lines of drug antitumor treatment and in the group of 3 or more lines compared with the use of only 1st line of treatment (p = 0.024) and (p = 0.003), respectively.

Conclusion. The results of the work demonstrate an advantage in the appointment of targeted therapy as the 1st and 2nd lines of drug antitumor treatment, while the appointment of chemotherapy remains a less prognostically favorable option. Adjuvant therapy administration did not demonstrate a statistically significant difference in relapse-free survival.
PIK3CA-mutated breast cancer: from research to clinical practice
Authors: Kornietskaya A. L. , Bolotina L. V. , Evdokimova S. F. , Savchina V. V. , Karagodina Yu. B. , Kachmazov A. A.
Published: December 2022

Mutation or amplification in the PIK3CA gene is one of the most frequent somatic mutations in hormone-dependent Her2neu-negative breast cancer (HR+ Her2neu- breast cancer) and is associated with an increased risk of relapse, progression or death. Understanding the mechanisms leading to hyperactivation of the PI3K-mediated signaling cascade has led to a new class of drugs aimed at inhibiting/suppressing it. Studies of the efficacy of the pan-PI3K inhibitor buparlisib and the beta isoform inhibitor taselisib were formally positive and reached their planned primary sites, but were discontinued due to high levels of toxicity. To date, the only phosphatidylinositol 3-kinase (PI3K) inhibitor approved in clinical practice is alpelsib, which selectively inhibits the alpha isoform of the enzyme's catalytic subunit. The efficacy and safety of alpelisib in combination with fulvestrant for the treatment of postmenopausal women and men with HR+ HER2- PIK3CA-mutated advanced or metastatic breast cancer after prior therapy with aromatase inhibitors was demonstrated in the SOLAR-1 study. The next step proving the efficacy of combination therapy in patients previously treated with endocrine therapy in combination with CDK4/6 inhibitors was the open, multicenter, noncomparative three-arm study BYLieve. The current accumulated clinical experience confirms and complements the findings. In this article, we review clinical cases of the use of alpelisib in patients who previously received hormone therapy, including CDK4/6 inhibitors.
Therapy of BRCA-associated metastatic breast cancer. Efficacy and safety of talazoparib in the real-world clinical practice
Authors: Lubennikova E. V. , Kornietskaya A. L. , Dorofeeva N. S. , Rossokha E. I. , Markarova E. V. , Yudina I. V. , Bazaeva I. Y. , Bolotina L. V. , Deshkina T. I. , Zhulikov Ya. A. , Stasenko E. V. , Ustinova T. V. , Tsareva A. S. , Artamonova E. V.
Published: December 2022

Introduction. PARP inhibitors demonstrated high efficacy in BRCA1/2-associated Her2-negative metastatic breast cancer (BC). They were included in the current standard chemotherapy regimen and recognized as a priority option for the treatment of such tumours following the results of clinical studies.

Aim. Review the experience with talazoparib (Talzenna) in the real-world clinical practice of 6 medical centers in Russia.

Materials and methods. The review included data from 29 patients with HER2-negative metastatic breast cancer associated with a gBRCA mutation, who have been receiving talazoparib therapy in 6 medical centers of Russia since April 2021. Talazoparib was given at the standard dose 1 mg once daily, the dose was reduced, if any adverse event developed.

Results. The median age of the patients was 50 years. 23 patients had a BRCA1 mutation, 5 patients had a BRCA2 mutation and one of the patients had a PALB2 mutation. Prior to starting talazoparib therapy, patients had received up to 9 lines of therapy for metastatic disease, the median was 1 line. The median follow-up period at that time was only 4.6 months. The median recurrence-free survival (RFS) was not reached. Progression was observed in 10 patients with a treatment period of 1 to 7.5 months, 19 patients continued to receive PARP inhibitor therapy without signs of disease progression, with a treatment period of 2 to 18 months. The objective response rate (ORR) was 57.2%, the clinical efficacy was confirmed in 85.7% of cases. The subgroup analysis showed that the lowest efficacy of therapy was reported in the group of patients, who had received prior therapy with platinum-based drugs, the median progression-free time (mPFT) was 4.5 months. (95% CI: 1.79-9.2). While for patients who had not received the prior platinum drug regimens, the median was not reached. Haematologic toxicities were common adverse events (AEs) for the talazoparib therapy, which were reported in 34.5% of cases. Transfusions of blood components were required in 3 patients, one of them required them repeatedly. All dose modifications were due to hematological toxicities. 7 patients (24.1%) required a dose reduction and 3 patients (10.3%) - repeated dose reduction.

Conclusions. Testing for BRCA1/2 mutations in Her2-negative mBC should be a mandatory diagnostic procedure. Talazoparib therapy is an effective and safe treatment option for patients with gBRCAmut HER2-mBC.
Real clinical practice patterns of palbociclib usage in Russian Federation
Authors: Frolova M. A. , Stenina M. В.
Published: December 2022

Introduction. Current treatment of metastatic luminal Her2-negative breast cancer includes combination of endocrine therapy (ET) with CDK4/6 inhibitors. This type of therapy demonstrated impressive efficacy over mono ET in early lines of treatment in phase III randomized clinical trials. Treatment patterns in real clinical practice (RCP) are of great interest. We represent the first available local data for all CDK 4/6 inhibitors in RCP in Russian Federation in accordance with the number of patients (pts).

Aim. Analysis of the patterns of palbociclib administration in RCP.

Materials and methods. One hundred and 5 pts from 12 regions of Russian Federation were included in this analysis and received palbociclib in combination with ET from 2017 to 2020. Median age was 57 years (29-75), 31/105 (29.5%) of pts were < 50. De novo metastatic disease was observed in 16 (15.2%) pts, 89 pts progressed after radical treatment. Visceral metastases (mts) at palbociclib initiation had 61/105 (58.1%) of pts.

Results. Only 22/105 (21%) of pts received palbociclib as 1st line treatment of metastatic disease. The majority of pts was treated with palbociclib in 2nd and 3rd lines (28.5% and 30.5% respectively). In 26/105 (24.8%) pts palbociclib was combined with aromatase inhibitors, in other cases - with fulvestrant. Median follow-up time was 6.5 (1.1-31.9) months, median progression free survival - 6.0 (1.0-28.0) months. Most common adverse events (AE) were leukopenia, neutropenia and thrombocytopenia. Only in 3 cases palbociclib was completely stopped due to toxicity.

Conclusions. Our data indicates that there is a need to move palbociclib initiation in first two lines of treatment to get maximal improvement in survival and to increase its usage in young women.
Reactualization of sunitinib in the treatment of metastatic renal cell carcinoma
Authors: Gritskevich A. A. , Baitman T. P. , Popov A. Yu. , Rusakov I. G. , Karelskaya N. A. , Chevina A. A. , Zholboldu P.
Published: December 2022

In recent years, the approach to the treatment of advanced renal cell carcinoma (RCC) has undergone significant changes. The introduction of targeted drugs in the systemic therapy of RCC in the 2000s began with tyrosine kinase inhibitors that replaced cytokines and had a revolutionary effect. Then the therapeutic arsenal was expanded with the introduction of doublets consisting of a combination of immune checkpoint inhibitors or immune checkpoint inhibitors and tyrosine kinase inhibitors. Tyrosine kinase inhibitors continue to represent an effective treatment option for metastatic RCC (mRCC), maintaining their position as first-line therapy in patients with a favorable prognosis. According to the CheckMate study, targeted therapy is highly effective, and the incidence of complications is generally lower than with nivolumab/ipilimumab combination therapy. Unlike dual immunotherapy, sunitinib does not expose patients with a favorable prognosis to undue risk of adverse events, while leaving more options for subsequent lines of therapy, and it's also often more cost-effective. The presented clinical observation is an example of successful monotherapy with sunitinib in a previously untreated mRCC patient with a favorable prognosis. This case is of particular interest due to the lesion of a single kidney and the patient's polymorbidity. Effective targeted therapy in the postoperative period had a positive effect on the quality and life expectancy.
Osmanlı’dan Cumhuriyete Anadolu’da Karga İstilaları ve Kargalara Karşı Yürütülen Mücadeleler (1860-1965)
Authors: OLGUN Said
Published: December 2022

Ekonomisi tarıma dayanan toplumlar çekirge ve domuz başta olmak üzere tarımsal üretime zarar veren çeşitli hayvanlara karşı yüzyıllar boyunca mücadele etmek zorunda kalmışlardır. Tarlalardaki ekinlere, bağ ve bahçelerdeki meyvelere zarar veren kargalar da tarım toplumlarının mücadele ettiği hayvanlardan biri olagelmiştir. Bu mücadele çoğu zaman çiftçiler ve halk eliyle sürdürülmüş; yerel ve mahalli yönetimler almış oldukları kararlar ve çıkarmış oldukları kanunlarla mücadelenin yasal ve idarî zeminini hazırlamışlardır. İdarî ve yasal düzenlemelerle mücadelenin kimler tarafından hangi şartlar altında nasıl gerçekleştirileceği belirlenmiş; ödül ve ceza mekanizması işletilerek halkın yürütülen mücadeleye katılımı teşvik edilmiştir. Kargalar yalnızca kırsal alanda geçimini çiftçilikle temin eden köylülerin değil aynı zamanda şehir ve şehirliler için de büyük bir sorun olabilmişlerdir.

Çalışmanın ilk kısmında Osmanlı Arşiv belgeleri üzerinden Osmanlı Devleti’nin son dönemlerinde Edirne ve İstanbul çevresinde karşılaşılan karga istilaları ve bunlara karşı alınan önlemler ve yürütülen mücadelelere değinilmiştir. İkinci kısımda ise Cumhuriyet döneminde Anadolu’nun çeşitli şehirlerinde yapılan mücadeleler dönemin ulusal gazeteleri ve Meclis Tutanakları üzerinden aktarılmaya ve değerlendirilmeye çalışılmıştır. Bu çalışmada Anadolu topraklarında bir zararlı olarak kargalara karşı yürütülen mücadeleler, halkın şikayetleri, alınan önlemler, idarî ve yasal düzenlemeler ile mücadele yöntemleri ve elde edilen sonuçlar aracılığıyla anlatılmaya ve değerlendirilmeye çalışılmıştır.
Abidin Özmen’in Maarif Vekilliği ve Faaliyetleri (1934-1935)
Authors: ORUN Özkan , YUCA İrşad Sami
Published: December 2022

Abidin Özmen, çöken bir devletin son yıllarında doğmuş olup eğitim ve bürokrasi hayatının ilk evresini bu kaotik süre zarfında yaşamıştır. Milli Mücadele ve Cumhuriyet dönemlerinde gerçekleşen askeri, siyasi, ulusal, laik ve modernleşmeye yönelik gelişmeler onun tutum ve düşünce dünyası üzerinde yeni ve kalıcı etkiler bırakmıştır. Özmen’in, Osmanlı’dan Cumhuriyet’e geçişte önemli görevlerde bulunmuş olmasının yanı sıra birçok toplumsal ve siyasal olaya da şahitlik etmiş olması onu yakın dönem Türkiye’sinin önemli bir profili kılmaktadır. Ayrıca görevleri icabıyla farklı bölge, şehir ve taşrada bulunup buraların toplumsal, kültürel ve yerel yaşantılarına tanık olması bir kez daha onun geride bıraktıklarını önemli kılmaktadır. Özellikle tek partili yıllarda ismi sıklıkla anılan, çalışkan bir siyasetçi ve bürokrat olmasının ötesinde devrin egemen ideolojisi olan Kemalist inkılâplara sadık birisi olduğu bir gerçektir. Kaymakamlık, mebusluk, umumi müfettişlik, valilik, maarif vekilliği ve Türk Dil Kurumu Başkanlığı gibi önemli vazifeleri üstlenmiştir. Özmen ile ilgili akademik ve genel çalışmalarda geniş bir literatür ortaya çıkarılmasına karşın bilhassa 1934-1935 yılları arasında gerçekleşen Maarif Vekilliği süresince eğitim ve öğretimin yaygınlaşması ve sorunlarının giderilmesi ile ilgili yürütmüş olduğu çalışmaların yeterince ele alınmadığı tespit edilmiştir. Bu çalışmada, Özmen’in hayatı, düşünce dünyası, bürokrasi ve siyasi hayatı bir bütün halinde kısaca ele alınmıştır. Ancak çalışmanın daha fazla odaklanacağı konu ise siyasi ve bürokratik hayatı içerisinde erken cumhuriyet yıllarının ilk yıllarında Türk maarifinin gelişmesine ve sorunlarının çözümünde yapmış olduğu çalışmalar üzerinedir.
Anadolu Türk Beyliklerinde Askerî Gelenekler-1 (Savaş Öncesinde ve Savaş Sırasında Uygulanan Gelenekler)
Authors: KAYA Kerim Köksal
Published: December 2022

İkinci devir Anadolu Türk beylikleri dönemi Anadolu Türk tarihinin önemli bir merhalesini teşkil etmekle birlikte genellikle bu hususta yapılan çalışmalar beyliklerin siyasî hayatları ve sanat tarihleri üzerinde durmaktadır. Bununla birlikte kaynakların sınırlılığına rağmen bu dönemin tarihi biraz irdelendiğinde Türk gelenekleri ve kültür tarihine dair son derece kıymetli malumata ulaşmak mümkündür. Nitekim ilgili beylikler Orta Asya Türk gelenekleri ve kültürüyle, ilk Müslüman Türk devletlerinin geleneklerinin ve kültürlerinin Anadolu üzerindeki taşıyıcıları ve hâmileri olmuştur. Yapılan bu çalışmada Türkiye Selçuklularının yıkılış sürecine girmesiyle birlikte Anadolu’nun muhtelif sahalarında ortaya çıkan beyliklerin askerî yapılarının bir tezahürü olan askerî gelenekleri ele alınacaktır. Bu konu hakkında yapılacak tam çalışma bir makale çalışması için oldukça hacimli olacağından burada sadece ilgili Anadolu Türk beyliklerinin savaş öncesinde ve savaş sırasında uyguladığı askerî gelenekler hakkında bazı örneklerle değerlendirmeler yapılacaktır.

Çalışma kapsamındaki beyliklerin ilk zamanlarında Türkiye Selçuklularına bağlı uç beylikleri oldukları göz önüne alındığında zaten onların mevcudiyetinin asıl amacının askerî faaliyetler olduğu (sınırları korumak, gazalara çıkmak vb.) anlaşılmaktadır. Bu amaç doğrultusunda teşkil edilen ve başlıca faaliyetleri askerlikle ilgili olan beyliklerin Türk askerî kültüründen uzak kalması pek olası değildir. Bu bağlamda Anadolu Türk beyleri hem Türkiye Selçuklularının hâkimiyeti altında ve hem de bağımsız oldukları dönemde sefer ve savaşların her aşamasında Türk askerî kültürüne sahip çıkmışlar ve bu kültürü zenginleştirmişlerdir.
Regional Identity in Strategy
Authors: Leukhova Maria , Gritskevich Tatiana
Published: December 2022

The article features the concept of regional identity in Kuzbass. On the one hand, regional identity is based on the policy of strategizing the management and promotion as part of the Regional Development Strategy through 2035. On the other hand, it reveals various semantic identity structures in the long-term strategic initiative of Kemerovo State as part of The Kuzbass Development Strategy through 2071. The analysis involved the challenges of systemic and functional problems of regional development that appeared as a result of socio-economic changes in the digital economy. It also described the projects of innovation and leadership centers. The authors believe that the traditional values and social meanings transform as a result of the state strategy aimed at increasing the competitive advantages of the regions. The theoretical and methodological basis of the study relied on the fundamental provisions of V.L. Kvint’s theory of strategy, certain methodological provisions of regional strategizing, the theory of social identity, and the mission of the region. The authors performed a selective OTSW analysis as an effective tool for monitoring and substantiating strategic opportunities. They constructed a model of regional development component that consisted of a system of social meanings. This system determined the joint efforts in achieving goals and the basic principles of ecology of interaction between flexible business strategies of regional companies, social movements, the youth, ambassadors of investment projects, etc. The approach provided a holistic vision of semantic orientation, which incorporated every stakeholder. Sustainable innovative strategies of regional development define the region as a unique territory with a unique socio-economic organization. They provide a single cognitive environment and a stable regional identity in determining the priority socio-economic bases for the integrative structures that trigger innovations. Strategic priorities in these areas ensure unique long-term development of the regions, as well as give the multiplicative impulse to the socio-economic development of the entire macroregion.
Strategic Analysis of International Trade Conflicts: Leading Economies and Their IT Industries
Authors: Evdokimov Dmitry
Published: December 2022

The difficult-to-control processes caused by trade wars and sanctions can be analyzed only post factum, since the large-scale state-level decisions need time to take effect. Modern trade-war methods usually include a collective pressure on the competing country, and the economic leverage is accompanied by the power politics. In recent years, national economies have undergone many crises, trade conflicts, and black swan events. The International Monetary Fund predicts no return to former economic growth rates. The IT industry is an advanced digitalization driver and a promising direction for state investments. The sphere of IT technologies will also have to adjust to the new circumstances. This study focuses on the IT industries of the world’s leading economies and the sanctions policy of the recent years. The research relied on domestic and international scientific papers, analytical reports, statistical collections, and expert assessments related to the topic of international trade wars, political sanctions, and the IT industry. The author considered international trade conflicts both diachronically and synchronically. The current state of the leading economies was described in terms of their GDP. Some experts report the low effectiveness of full-scale sanctions in defending political and economic interests. Since Western Europe and the United States were responsible for most trade wars in the past, they probably find this mechanism beneficial in conducting a dialogue with their opponents. The author believes that the IT industry will be able to adapt to the new economic reality as the era of the unipolar world imposed by the United States is fading into history, triggering inevitable changes in the international economic relations.
¿Se requieren direcciones de enfermería en Colombia?
Authors: Torres Panesso Martha Cecilia , Agudelo Agudelo Yurley María , Berbesi Fernandez Dedsy Yajaira
Published: December 2022

En la actualidad son diversas las necesidades que surgen ante los cambios políticos y gubernamentales en el sistema de salud, lo que exige para el profesional de enfermería, de una formación a profundidad que le permita la gerencia del cuidado en las diferentes áreas de desempeño, buscando la gestión de los recursos humanos, físicos y financieros para dar respuesta a las demandas del entorno, conservando en su marco de actuación los referentes de un cuidado humanizado, y una participación activa en la toma de decisiones en el nivel estratégico de las organizaciones, así como un liderazgo con el personal comprometido en los procesos de cuidados de los pacientes, sin dejar de analizar el escenario y contexto de incertidumbre actual.
Por ello, este artículo presenta una reflexión acerca de la necesidad imperante de fortalecer las direcciones de enfermería en Colombia como un factor esencial para el desarrollo de las organizaciones de salud, en la medida que integra acciones de gerencia del cuidado en el ámbito organizacional, teniendo en cuenta los elementos que caracterizan la profesión de enfermería y la necesidad de la formación post gradual en profundidad en esta área para contribuir al desarrollo de la profesión y al mejoramiento de los indicadores de enfermería durante la atención en salud.
FACTOR INFLUENCING COMPLIANCE OF MASK USAGE AMONG BANGKALAN SUB-DISTRICT COMMUNITY DURING COVID-19 PANDEMIC
Authors:   Bachelor's Degree Study Program of Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia, Asmy Hatimul , Setijowati Nanik ,   Departement of Public Health and Preventive Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia, Novita Khuznita Dasa ,   Departement of Family Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia
Published: December 2022

Bangakalan Sub-district occupies with the most patients infected by COVID-19 in Bangkalan Regency. Meanwhile, Bangkalan Regency itself has a significant number of COVID-19 patients. Various efforts are continuously have been done to control the rate of COVID-19 transmission, and one of the efforts is mask usage. Mask usage compliance can be influenced by several factors. This study aimed to find out which factors can significantly influence mask usage among the Bangkalan Sub-district community. This study used an analytical observation with a cross-sectional approach and obtained 100 samples. The number of respondent who compliant were 32 people (32%) (male 8 (8%), female 24 (24%), moderately compliant 33 people (9% male (9%), female 24 (24%)) and 35 people less compliance (male 13 (13%), female 22 (22%)). Based on the crosstab analysis Chi square test, only enabling and reinforcing factor that correlated with mask usage compliance. In enabling factor, there are two elements that are significantly related to mask usage compliance : providing spare masks whenever leaving the house (p-value=0,027) and good mask maintenance (p-value=0,000). In reinforcing factor, there are two elements that are significantly related to mask usage compliance : receiving warnings on mask usage from co-workers/schoolmates/college friends (p-value=0,002) and receiving warnings on mask usage from community leaders (p-value=0,040). The ordinal regression analysis showed factors that did not significantly influence mask usage compliance were predisposing factor (p-value = 0,452) and enabling factor (p-value = 0,527). Meanwhile, reinforcing factor (p-value = 0,001) significantly influenced mask usage compliance. When these three factors were described, the results of the ordinal regression showed ease of getting mask (p-value = 0,000), good mask maintenance (p-value = 0,037), receive warnings through social media (p-value = 0,043), and recieving warnings from the community leaders (p-value = 0,046) significantly influenced mask usage compliance among Bangkalan Sub-district community during COVID-19 pandemic.
Women and nationalism in Poland: Defending the dignity of Polish women
Authors: Sygnowska Aleksandra
Published: December 2022

This article aims to explain the role of women involved in right-wing political parties and explore how women themselves legitimise the politics of exclusion through their political involvement. Its main assumption is that, on the one hand, Polish women in politics eagerly benefit from the feminist legacy in their own political careers, and, on the other, as representatives of right-wing political parties with traditionally antifeminist agenda, they significantly contribute to the radicalisation of politics.To show the discursive intersections of gender and nationalism and their impact on the public discourse, I analyse narrative strategies applied by Polish right-wing female politicians in their public, media, and parliamentary appearances. I claim that, having access to and control over public discourse, Polish right-wing female politicians play a prominent role in social mobilisation and, thereby, make an important contribution to the nationalist surge that sweeps Poland.
Staycation: A Domestic Wellness Tourism among Malaysian and Singaporean
Authors: Chong Kim Mee , Tan Tze Horng , Ating Rashid , Fong Sook Fun , Ong Yi Xuan
Published: December 2022

One phenomenon observed during the pandemic was increased staycation in most countries. This study focuses on wellness tourism through staycation in Malaysia and Singapore. A self-administered online questionnaire was completed by 109 Malaysians and 60 Singaporeans. Using IBM SPSS and SmartPLS, the determinants examined were the sense of presence, experience quality, hedonic motivation, and psychological detachment and mediated by family involvement towards the gratification of wellness tourism. This study contributes to theory and practices for Malaysia and Singapore's domestic tourism and the United Nations' Sustainable Development Goals 8 and 12 for mental well-being and responsible consumption.
Keywords: staycation, wellness tourism, use and gratification, domestic tourism
eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under the responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v7i22.4156
Implication of Personalized Advertising on Personal Data: A Legal Analysis of the EU General Data Protection Regulation
Authors: Basarudin Noor Ashikin , Raji Ridwan Adetunji
Published: December 2022

p>The accelerating emergence of personalised advertising is mostly driven by data. Accordingly, algorithmic profiling has become a constant experience for every online user in predicting preference and interest. The profiling process raises several issues of human privacy and personal data invasion. Therefore, this study adopts the doctrinal legal method through the analysis of International Instruments and the European Union General Data Protection Regulation as legal avenue to safeguard and protect online activities of the data subjects. The findings of this paper discuss the main principles to be observed by the data controller in ensuring the legality of personal data profiling. This paper suggests the profiling process to be design-based security due to unavailability of system procedure to human knowledge.   
Keywords: Personalised Advertising; Algorithmic Targeting; Personal Data Profiling; EU General Data Protection Regulation
eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v7i22.4160
Environmental Noise in Residential Environments: The Case for Quality of Life in Minna, Nigeria
Authors: Akande Oluwafemi Kehinde , Yusuf Abdullahi
Published: December 2022

Environmental noise pollution lowers the quality of life and is a public health concern in residential areas. In Minna, Nigeria, the effects of exposure to noise pollution on inhabitants' health and well-being were examined in this study. The indicated maximum limits for tolerable noise levels for quality of life in a home context were exceeded by the noise data measured using a sound level meter, a hand-held geographic positioning system, and a structured questionnaire (N = 880). The study recommended the design of noise-absorbing buildings, improved urban and infrastructure planning, and noise-regulating measures
 for a considerable increase in the quality of life of people.
Keywords: Environmental noise; Public health; Quality life; Residential environment
eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v7i22.4161
Establishing Infodemic Management in Germany: A Framework for Social Listening and Integrated Analysis to Report Infodemic Insights at the National Public Health Institute (Preprint)
Authors: Boender T Sonia , Schneider Paula Helene , Houareau Claudia , Wehrli Silvan , Purnat Tina D , Ishizumi Atsuyoshi , Wilhelm Elisabeth , Voegeli Christopher , Wieler Lothar H , Leuker Christina
Published: December 2022

BACKGROUND

To respond to the need to establish infodemic management functions at the national public health institute in Germany (Robert Koch Institute, RKI), we explored and assessed available data sources, developed a social listening and integrated analysis framework, and defined when infodemic management functions should be activated during emergencies.

OBJECTIVE

We aimed to establish a framework for social listening and integrated analysis for public health in the German context using international examples and technical guidance documents for infodemic management.

METHODS

This study completed the following objectives: identified (potentially) available data sources for social listening and integrated analysis; assessed these data sources for their suitability and usefulness for integrated analysis in addition to an assessment of their risk using the RKI’s standardized data protection requirements; developed a framework and workflow to combine social listening and integrated analysis to report back actionable infodemic insights for public health communications by the RKI and stakeholders; and defined criteria for activating integrated analysis structures in the context of a specific health event or health emergency.

RESULTS

We included and classified 38% (16/42) of the identified and assessed data sources for social listening and integrated analysis at the RKI into 3 categories: social media and web-based listening data, RKI-specific data, and infodemic insights. Most data sources can be analyzed weekly to detect current trends and narratives and to inform a timely response by reporting insights that include a risk assessment and scalar judgments of different narratives and themes.

CONCLUSIONS

This study identified, assessed, and prioritized a wide range of data sources for social listening and integrated analysis to report actionable infodemic insights, ensuring a valuable first step in establishing and operationalizing infodemic management at the RKI. This case study also serves as a roadmap for others. Ultimately, once operational, these activities will inform better and targeted public health communication at the RKI and beyond.
High levels of Cyber-Addiction among female physical education Students: Insights and Implications from a Pilot
Cross-Sectional Study (Preprint)
Authors: Bragazzi Nicola
Published: December 2022

UNSTRUCTURED

Background: Cyber-addiction has become a particularly serious problem among students around the world. However, few researchers have investigated cyber-addiction and its impact on Tunisian university students. Aims: Our study aimed to assess the presence and severity of internet addiction among Tunisian university students. Methods: 540 students from Sfax, Tunisia (191 males, 35.4% and 349 females, 64.6%) aged from 18 to 30 years, with a mean age of 21.72 ± 1.93 years, participated voluntarily to our study. They were administered the French version of the "Internet Addiction Test" (IAT). Results: Mean IAT score resulted 65.02 ± 19.71 (median 68). Exploratory and confirmatory factor analyses enabled to discover a 1-factor structure. Overall reliability proved excellent, as shown by the Cronbach’s alpha (0.93) and by the test-retest correlation (0.73). Almost half of the students (42.8%) were found to be cyber-addicted, with females being much more affected than males (respectively 30.9% versus 11.9%). Together with gender, age was found to be another determinant of cyber-addiction, with students aged less than 20 years exhibiting a higher risk than students aged 20 years and older. Conclusion: The IAT proved to be a reliable instrument that can be administered to Tunisian students. Moreover, our results showed that cyber-addiction has become a widespread phenomenon also among Tunisian university students.
Title: Characterizing the most influential voices driving Twitter discourse about tobacco regulatory policy from September 2019 – July 2021 (Preprint)
Authors: Silver Nathan , Feng Miao , Kierstad Elexis , Tran Hy , Binns Steven , Emery Sherry , Schillo Barbara
Published: December 2022

BACKGROUND

Twitter is an important avenue through which tobacco regulation evolves in the public consciousness. That said, prior research has identified the spread of mis and dis-information regarding tobacco products on Twitter and a possibly disproportionate influence of e-cigarette advocates on the platform taking an anti-regulatory stance.

OBJECTIVE

To examine the most influential users discussing tobacco regulation on Twitter.

METHODS

We used a keyword filter (F1 = .91) to identify N=3,159,807 tobacco-policy tweets by n=58,369 users from the full corpus of tobacco-related content between the vaping-associated lung injury outbreak starting in August 2019, continuing through the period before (period 1), during (period 2), and after pandemic stay-at-home orders (period 3), and through the months following vaccination rollout, up to July 2021. Top users by retweets and sustained influence (H index) were identified and coded.

RESULTS

Total posts and retweets received were heavily concentrated among the top 100 users at each of three time periods. The top 100 most retweeted users posted 8.5%, 21.4% and 34.6% of all original tweets during periods 1, 2 and 3, respectively and 56%, 48%, and 70% of all retweets. The 100 users with the top H index posted 8.3% of all content, 17.5%, and 27.3% with those posts accounting for 23.1%, 37.5%, and 16.9% of all retweets received during each period respectively. After coding user profiles, e-cigarette advocates comprised 44.5% (n=146) of top H index unique users across all three time periods.

CONCLUSIONS

While both the number of posts and number of users discussing tobacco policy on Twitter declined sharply with the onset of the COVID-19 pandemic, e-cigarette advocates continued to dominate both top 100 retweet and top 100 H index groups revealing the strong influence of anti-tobacco regulation advocates on Twitter.
Spiritual Leadership dalam Organisasi : Faktor Pengaruh dan Arah Penelitian Masa Depan
Authors: Yulianti Padmi Dhyah , Suhariadi Fendy , Hadi Cholichul , Surjaningrum Endang Retno , Sugiharto DYP
Published: December 2022

Organisasi dalam menyongsong era industri 4.0 memiliki beragam tantangan. Salah satu tantangan sosial yang dihadapi berkaitan dengan kepemimpinan. Dari banyak teori kepemimpinan, spiritual leadership merupakan salah satu gaya baru kepemimpinan yang dapat diterapkan karena lebih berorientasi pada nilai–nilai kesejahteraan. Penelitian ini bertujuan untuk : 1) mengidentifikasi berbagai macam faktor spiritual leadership, serta 2) rekomendasi penerapan spiritual leadership untuk penelitian masa depan. Metode yang dipergunakan adalah telaah literatur. Hasil penelitian menyebutkan spiritual leadership memengaruhi beberapa variabel seperti misalnya: kualitas kehidupan kerja, kepuasan kerja, perilaku etis, penyimpangan perilaku di tempat kerja, spiritualitas di tempat kerja, perilaku keselamatan karyawan, budaya sekolah, kesuksesan akademis, kelelahan, keterlibatan kerja, niat karyawan untuk tetap bersama organisasi, serta rasa panggilan kerja. Rekomendasi penelitian spiritual leadership pada masa depan pada kajian metodologis serta pengembangan teori.
Mismatch Negativity (MMN): Komponen Event-Related Potentials (ERP) sebagai Penanda Aktivitas Otomatis Otak dalam Mendeteksi Perubahan
Authors: Khakim Zulfikri , Honbolygó Ferenc
Published: December 2022

Agar dapat berinteraksi secara efisien terhadap banyaknya informasi sensori, otak memiliki strategi heuristis yang dapat menyaring informasi sekaligus mengarahkan atensi ketika muncul informasi yang penting dan krusial. Penelitian tentang otak telah mengungkapkan salah satu penanda atas sistem tersebut, yang disebut sebagai Mismatch Negativity (MMN). MMN merupakan salah satu komponen dari Event-Related brain Potentials (ERP) yang diasosiasikan dengan penanda sistem pendeteksi perubahan dan pelanggaran tiba-tiba terhadap aturan abstrak dari stimulus suara, dan dapat digunakan sebagai indikator objektif mengenai akurasi diskriminasi suara, sensori memori, maupun proses praatensi. Komponen MMN muncul sebagai gelombang negatif yang terpicu oleh stimulus yang menyimpang dari keteraturan. Metode MMN telah banyak digunakan dalam berbagai bidang penelitian hingga konteks klinis. MMN juga merupakan metode yang sangat bermanfaat untuk menyelidiki mekanisme pemrosesan kognitif pada populasi yang memiliki kesulitan untuk mengikuti prosedur eksperimen, misalnya pada anak-anak, atau pasien klinis karena sifatnya yang otomatis dan tidak membutuhkan atensi. Artikel ini bertujuan untuk memberikan pengenalan mengenai konsep dan prinsip dasar dalam MMN, paradigma eksperimen, hingga contoh aplikasi, dan potensi penelitian yang dapat dilakukan menggunakan metode ini.