bluuebunny/crossref_metadata_2025 huggingface dataset:
Experience in the use of low-temperature plasma in the therapy of radiation reactions.
Authors: Evstigneeva Inna S. , Kozyreva Valeriia O. , Gerasimenko Marina Yu.
Published: September 2022

The use of low-temperature plasma is a modern and developing direction in medicine, including rehabilitation. Low-temperature plasma (LTP) has a high antiseptic, wound-healing activity, and is also a safe method of physical exposure. In the in-patient facility of clinical unit of Federal State Budgetary Educational Institution of Further Professional Education Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation named after Prof. Yu.N. Kasatkinа, a patient was treated with low-temperature argon plasma after selective right cervical lymph node dissection, resection of the mandible, and tissues of the oral floor with defect plasty with a fibular autograft for cancer of the gingival mucosa of the mandible on the right pT4aN0M0, stage IVa. In the process of EBRT (external beam radiation therapy), the patient developed a complication in the form of a local radiation reaction with the formation of a fistulous opening in the area of the postoperative scar. The fistulous opening and the affected area were treated with a cooled air-plasma flow. During the continued use of LTP, the termination of pyorrhea, a decrease in hyperemia and edema in the area of tissues damaged by ionizing radiation were noted. The patient was promptly continued radiation therapy.
Thus, the use of this therapeutic factor in the program of medical rehabilitation is an effective way of local impact on the pathological focus, allows you to achieve a quick reparative effect, eliminates and prevents the development of bacterial complications. In addition, the use of an air-plasma flow contributes to the rapid relief of manifestations of radiation reactions, having a beneficial effect on damaged tissues, as well as shortening the rehabilitation period for severe cancer patients in the postoperative period and during the course of EBRT. The results of LTP action have a positive effect on the general condition of patients and improve their quality of life.
Low-frequency magnetotherapy with a running magnetic field of the POLYMAG-02M apparatus in the rehabilitation of patients after COVID-19
Authors: Larinsky Nikolay E. , Larinskaya Irina K. , Byalovsky Yuriy Yu.
Published: September 2022

BACKGROUND: COVID-19 is an infectious viral disease caused by SARS-CoV-2 virus with high morbidity and mortality, especially among the elderly and those with concomitant factors such as diabetes mellitus, chronic lung and heart disease. For patients who have undergone coronavirus pneumonia, given the severity of the disease, rehabilitation measures are needed to restore the consequences of the disease.
AIMS: To evaluate the effectiveness of the use of low-frequency magnetic therapy with a running magnetic field in the complex of rehabilitation treatment of patients who have undergone pneumonia caused by SARS-CoV-2 (COVID-19) at the stage of convalescence.
MATERIAL AND METHODS: Examination and treatment of 42 patients (24 men and 18 women) aged 40 to 65 years, who had community-acquired pneumonia (J16.8) caused by the new coronavirus SARS-CoV-2 (COVID-19), were carried out. The first (main) group of patients included 22 people who underwent physical therapy, aeroinotherapy, low-frequency oscillatory massage of the chest in an electrostatic field, intravenous laser blood irradiation, high-frequency oscillation of the chest and carbon dioxide baths. Against this background, starting from the 20th day after discharge from the hospital, this group of patients received low-frequency, low-intensity magnetotherapy from the POLIMAG-02M apparatus. The second (control group) included 20 patients who received the same treatment, except for magnetotherapy from the POLIMAG-02M apparatus.
RESULTS: The course of rehabilitation treatment led to an increase in the functional capabilities of the cardio-respiratory system in patients of both groups, an increase in chest excursions, an increase in the vital capacity of the lungs, the normalization of the act of breathing and ventilation of the lungs, and an improvement in the psychosomatic status of patients. In the main group, these changes are more pronounced than in the control group, which is associated with the inclusion of low-frequency magnetotherapy with a running magnetic field in the complex treatment.
CONCLUSION: The use of low-frequency magnetic therapy with a running pulsed magnetic field in the complex of rehabilitation measures for patients who have undergone pneumonia caused by the COVID-19 virus significantly improves the somatic status of patients, increases exercise tolerance, and optimizes the function of external respiration. The data obtained make it possible to recommend the inclusion of the factor in clinical guidelines for the rehabilitation of patients who have undergone COVID-19.
terror, a piedade e a verossimilhança
Authors: Amaral Leonardo Brandão de Oliveira , Martins Edson Soares
Published: September 2022

Para além de reconhecer a permanente relevância de uma das obras precursoras dos estudos voltados ao problema da criação literária, a Arte Poética, de Aristóteles (1993), este artigo dispõe-se a explorar pontos de interesse e aproximações conceituais entre as teorias do fantástico e o texto do filósofo grego. Propõe-se, a caminho de uma compreensão do quadro, um alinhamento comparativo de suas semelhanças, a fim de demonstrar a recorrência e a pertinência que alguns elementos críticos assumem nessas duas diferentes tradições da poética. Nota-se, nesse processo, três elementos recorrentes nas propostas teóricas e em seus objetos: o terror, como efeito a ser alcançado no receptor; a piedade, como relação desejada entre o interlocutor e a realidade das personagens representadas; e a verossimilhança, como elemento necessário para a realização dos dois efeitos anteriores.
Luís Gama e a Pretidão de Amor
Authors: Camilo Vagner
Published: September 2022

O ensaio examina um poema erótico-amoroso de Luís Gama não incluído no único livro que ele chegou a publicar em vida. A análise se ocupa do intertexto camoniano, buscando demonstrar como Gama subverte de forma ainda mais radical a convenção petrarquista em comparação com as “Endechas a Bárbara escrava”, do renomado poeta português, com as quais dialoga de perto.
último soneto de Manoel Botelho de Oliveira (ca. 1706)
Authors: Rodrigues-Moura Enrique
Published: September 2022

Este artigo apresenta um soneto pouco conhecido de Manoel Botelho de Oliveira (Salvador da Bahia, 1636-1711), escrito em louvor ao folheto Patrocínio empenhado pelos clamores de um preso, de autoria de Félix de Azevedo da Cunha e impresso em Lisboa em 1706. Portanto, além da comédia em castelhano Hay amigo para amigo (Coimbra, 1663) e do livro de versos poliglotas Música do Parnaso (Lisboa, 1705), que também inclui duas comédias em castelhano, este soneto é o terceiro texto de Botelho de Oliveira que chegou a ser impresso em vida. Edita-se e comenta-se este soneto, a partir de dados históricos e por meio de uma interpretação filológica, na linha da crítica textual. Os dados históricos conhecidos e o estudo filológico do poema permitem afirmar que Botelho de Oliveira passou os últimos anos da sua vida desfrutando da sua condição de homem da governança da Cidade de Salvador da Bahia, enquanto se preocupava por deixar um legado literário para a posteridade.
The role of parental involvement and mathematics self-concept of elementary school students in online mathematics learning
Authors: Purnomo Y. W. , Apriyanti N. , Mubarokah S. A. , Susilowati . , Anggraheni W. A.
Published: September 2022

Introduction. Learning mathematics from home during the COVID-19 pandemic is a challenge for both parents and students to manage to engage in learning. Therefore, it is important to examine the involvement of parents in learning mathematics from home and students’ mathematics self-concepts and their relationship to mathematics performance.

Aim. This study is aimed to analyse parental involvement and students’ mathematical self-concept, the relationship between the two, and their effect on students’ mathematical performance in online learning.

Methodology and research methods. A cross-sectional survey was used to achieve the research objectives. There were 56 elementary school students in rural areas who were involved in this study. To assess parental involvement and mathematics self-concept, the authors employed questionnaires. Meanwhile, the results of the mid-semester test were used to assess student math performance. The answers to the research questions were reported using descriptive analysis, correlation, regression, and the t-test.

Results. Based on the results of the analysis, parental involvement, both in terms of support and control aspects, has a significant influence on mathematics performance. On the other hand, mathematics self-concept and performance positively influence each other. The findings of the present research also show that the gender group and grade level group did not have significant differences for each variable.

Practical significance. This study has implications for schools to maximise parental involvement in their children’s mathematics learning effectively. Communication between schools, teachers, and children, in particular, becomes critical to maximise children’s potential, including their math self-concept.
Abraham Flexner: trayectoria de vida de un educador
Authors: Spinelli Hugo
Published: September 2022

Este trabajo se enfoca en la trayectoria de vida de Abraham Flexner, conocido en el campo de la salud por el Informe Flexner, publicado en 1910, considerado como una de las discusiones teóricas más importantes en la historia de la educación médica. Flexner fue ante todo un educador, perteneciente al movimiento progresista de educación en EEUU, encabezado por John Dewey. A lo largo del texto se analiza el momento histórico en que se inicia la conformación del campo de la salud en EEUU, sus actores, los intereses en juego, la constitución de la doxa, el rol de las fundaciones filantrópicas y de la American Medical Association. Las críticas de Flexner en el campo de la educación se centraron en los métodos pedagógicos en los diferentes niveles educativos, siendo especialmente crítico de la universidad, los posgrados y la ausencia de una formación humanista, desplazada por la investigación. La pregunta final del artículo es si los problemas enunciados por Flexner sobre la educación en general y la educación médica en particular entre fines del siglo XIX y principios del siglo XX, tienen aún vigencia en las escuelas de medicina y universidades de los países de América Latina.
Challenges in the New Norm for Water Consumption in Thermal Power Stations in India – A Review of Strategies for Adoption
Authors: Kumarasamy M.
Published: September 2022

No Abstract.
Applied Research on Underpinning Technology for Protection of Structure Closed to Deep Excavation
Authors: Shao Guangbiao , Zhou Jialin
Published: September 2022

Building structures are insecurity when it is closed to foundation pit, which likely to collapse or produce large deformation due to design or construction faults. Dead loads of structures applied on the top of pit slope and add the probability of circular sliding of slope. Underpinning technology can transfer loads to the deeper soil layer and deformation had been restrained effectively. With the development of foundation underpinning technique, more and more mini-pile should be drilled through the foundation inner or outer buildings structures. When the structures protected by underpinning method, the foundation pit supporting project can be designed more easily and flexibly. By one engineering example, underpinning technology and foundation pit supporting technology are combined and applied to protect the stability of structures near the pit. Using the united method, the loads of structures are transferred vertical and pressure on the top is reduced highly, active earth pressure is lower at the same time, so that the excavation stability can be achieved more easily. The engineering examples provide better technical references for similar projects.
Self-Powered Skin Electronics for Energy Harvesting
Authors: Bhattacharya Jayanta
Published: September 2022

No Abstract.
The Turning Point in Indian Environment
Authors: Thangamuthu A.
Published: September 2022

The human life in the earth may be continued without water for few days, without food for few weeks. However the human life in the earth may not be continued for few minutes without air. Air comes under. 24 ? 7 in our human system. In such condition, air plus sulphur dioxide is harmful to respiratory system which leads to premature deaths and reduction in life expectancy. It is a big shock to the nation that India becomes the highest emitter of sulphur dioxide of the world, surpassing the China. It is not a encouraging trend for us. Under these circumstances MOEF and CC has notified the norms for various pollutants including sulphur dioxide emission from thermal power plants in December 2015. The norms cover various size plants for various periods with various levels of emission, with a timeframe of two years as implementation schedule. This notification is a correct notification in correct direction, but with some time delay. This notification has put about 1800000 MW in study mode, mainly of coal fired units in nature. The sulphur dioxide emission may be well controlled by installing flue gas desulphurisation (FGD) system in boiler flue gas path. By injecting lime in the flue gas path, sulphur dioxide is converted to calcium sulphite and then by reacting with oxygen, it is converted to calcium sulphate. Thus the flue gas is purified from sulphur dioxide. India has to import this technology. Technology transfer is a difficult task especially on commercial terms. This article narrates the various happenings in the country after the publication of notification.so that the reader gets the overall picture in single presentation. The implementation of the flue gas desulphurisation (FGD) system in Indian thermal power plants as early as possible, may improve the environment prevails in the country. This paper deals with various issues related to Sulphur dioxide emission and reduction measures.
Environmental Issues and Challenges for Coal/Lignite based Thermal Power Plants and Mitigation Measures
Authors: Raghuthaman S.
Published: September 2022

The world is undergoing a massive energy transition. Over the next decades, there will be radical changes in the way we produce and consume energy. The conventional energy infrastructure being set up now would be abandoned ever before their economic life is over. A quarter of India’s population have no access to electricity and our per capita consumption of electricity is very low at almost one third of world average with millions getting power a few hours a day. Surprisingly the plant load factor (PLF) for thermal power plant have steadily declined over the last four years and was only 63.6% in Sep. 2015. Breakthrough in solar plant technology posed a challenge for fossil fuel based thermal power plants. In April 2017, the tariff of utility connected large solar power projects in India hit a record low of Rs.3/kWh. This is the same as the average tariff of coal based power. At this tariff, solar plants are cheaper than a large number of new and old coal fired power plants in India.Stringent pollution norms add to the cost of generation of thermal power. Several projects in the power sector have become unviable on account of states like Andhra Pradesh, Uttar Pradesh and Karnataka have either cancelled the power purchase agreement or reworking on them. Few more states may follow in cancellation of power purchase agreement (PPA). Distribution Companies (DISCOMS) are reluctant to sign PPA because of high tariff, demand uncertainties, long duration of PPA and need to take the responsibility of fixed charges for the life of PPA. This will lead to creation of non-performing asset (NPA) worth Rs.1.5 lakh crores and to the extent the bank loans will be at risk.Some mitigation measures are suggested to meet the challenges in operation of coal/lignite based thermal power plants.
Analysis of Evolutionary Game on Construction of Dynamic Alliance of Engineering Project
Authors: Wei Sun , Zhang Yujuan , Ma Xiaoli
Published: September 2022

The paper constructs an evolutionary game model on dynamic alliance of engineering project and analyzes the process of the game. Finally, it is concluded that the expected return, risk and alliance resources are the important factors that affect dynamic alliance of engineering project. On the basis, a solution of dynamic alliance is proposed to accelerate the development of the construction.
Grid Solar Installations can be Anti-Micro/Macro Biological Environment, and What are the Choices
Authors: Bhattacharya Jayanta
Published: September 2022

No Abstract.
Recent Developments of Inductive Pad for Charging of Electric Vehicles (EV)
Authors: Bhattacharya Jayanta
Published: September 2022

No Abstract.
Exploring the Leading Role of Government in Renewable Energy Financing
Authors: Ahuja Nupur
Published: September 2022

No Abstract.
Internet of Things (IoT) Role Play in Energy Management System
Authors: Coumarane M. , Manoharan V.
Published: September 2022

Internet of things (IoT) is the network of physical object-devices. IoT connects billion of devices via internet in the present network scenario. Interoperability, data exchange and communication features bring the devices in a network. IoT plays a vital role in energy management system (EMS). Online monitoring of remote energy meter through internet and sending SMS message to operator in case of power failure are the attractive feature of the EMS-IoT. Energy management system is the today need of the day in the context of energy security and global warming issues. Energy conservation and energy efficient measures are the key objective of energy management system.
Innovative Modifications in LHS and ESP Controls with a View to Improve Reliability, Availability and O&M Efficiency
Authors: Kamalraj D. , Ganesan P.
Published: September 2022

No Abstract.
Integration and Flexibilization of Steam Power Plants with Growing Renewable Energy Systems
Authors: Srinivasan G.
Published: September 2022

Increasing the flexibility of conventional power plants is one key challenge for the massive integration of highly volatile renewable energy resources into the Indian power system. Flexible power plants ensure the security of supply by compensating fluctuations in the electrical grid caused by intermittent renewable energy production from wind and sun. In this paper, the future development of the Indian electricity market is predicted and evaluated in terms of the future flexibility demand of coal and Lignite-fired power plants. As the flexibility measures for coal-fired power plants generally use inherent capabilities of the existing power plant systems, they are usually restricted by limiting factors. Here, the limiting factors for reducing the minimum load and increasing load change rates are discussed and potential measures to mitigate their influence are presented. An alternative way to increase the flexibility lies in properly integrating thermal energy storages. Integrating this storage concept the electrical minimum load can be reduced while simultaneously increasing the load change rate.
Measures to use Electroceuticals and Secure Social Reliability in Korea: A Narrative Review
Authors: Park Sam-Hun , Shim Jiwon
Published: September 2022

Background: The purpose of this study was to present a plan for utilizing electroceuticals to secure social reliability in Korea by investigating and analyzing the trends of humanities and social science research in Korea regarding electroceuticals. 
Methods: The present situation of academic papers in the fields of humanities and social sciences that had researched electroceuticals in Korea and the topics that were directly related to electroceuticals had been reviewed and analyzed.
Results: Regarding researches related to electroceuticals in the fields of humanities and social sciences in Korea, they were insufficient quantitatively. Qualitatively, they had leaned too much toward theoretical and abstract discourses regarding neuroethics and neurophilosophy. 
Conclusion: If researches in the fields of humanities and social sciences known to play a role in preparing practical guidelines could be carried out sufficiently while preparing a base for solving actual problems raised by electroceuticals, they could actually help plan a specific electroceuticals policy and a law to secure social reliability. Among principles of general life medical ethics (principles of biomedical ethics), when considering the principle of justice, the investment by the Korean government regarding research and development of electroceuticals, the rationalization of electroceuticals regulations, the application of electroceuticals of public health insurance benefit, and voluntary efforts of electroceuticals corporations are important in order to have strong plans for securing the social reliability of electroceuticals.
Spleen Stiffness on Magnetic Resonance Elastography for the Detection of Portal Hypertension: A Systematic Review and Meta-Analysis
Authors: Yiyi Ma , Xiaoqin Qian , Lei Zhang
Published: September 2022

Background: Chronic liver disease, complicated by portal hypertension (PH), may alter the extra-hepatic hemodynamic condition and spleen stiffness (SS). We aimed to evaluate the diagnostic accuracy of MRI-based elastographic methods (MRE) for detecting PH.
Methods: Seven studies were included with reference to SS with regard to the prediction of PH patients. Major outcomes considered for data extraction were diagnostic parameters for MRI for concluding mild PH, clinically significant PH and severe PH. PubMed, Scopus, Google Scholar, Cochrane and Science Direct databases were used to extract the published literature through to May, 2021Using the Rayyan Zotero and R softwares.
Results: Out of 587 studies extracted, 7 were selected based on inclusion and exclusion criteria. A QUADAS-2 assessment showed that all studies were clear in terms of patient selection and reference standard. A funnel plot showed that all the selected studies were outliers, indicating a low level of accuracy for the studies included. Subgroup analysis, with reference to SS as a predictor of PH, revealed raw mean difference (RMD) of 7.78% (95% CI 5.23-10.34, P<0.01). The corresponding RMD observed for <60 years and >60 yr were 34.26% (95% CI 9.33- 59.20, I2=100%,  T2=646.7688, P=0), and 46.92% (95% CI 20-59.33, I2=97%, T2=1003.023, P=0) respectively. The specificity and sensitivity noted for MRI in determining SS were 0.721 and 0.747, respectively with an area-under the curve of 0.788. The estimated random effect models for specificity and sensitivity were 0.938 and 0.842, respectively.
Conclusion: The real-time MRE has acceptable specificity and sensitivity for diagnosing SS.
Milk as a Non-Invasive and Alternative Sample for Serum in the Diagnosis of Animal Toxoplasmosis: A Systematic Review
Authors: Nayeri Tooran , Sarvi Shahabeddin , Abedian Rohallah , Gohardehi Shaban , Hosseini Seyed Abdollah , Daryani Ahmad
Published: September 2022

Background: Toxoplasmosis is one of the most important zoonotic parasitic diseases worldwide with a high impact on human and animal health. Body fluids such as milk are used to diagnose many parasitic diseases, including toxoplasmosis. Therefore, this study aimed to investigate the role of milk as a non-invasive and alternative sample for serum in the diagnosis of animal toxoplasmosis.
Methods: Five English-language databases (ScienceDirect, PubMed, ProQuest, Scopus, and Web of Science) were explored for published articles before Dec 2020.
Results: In total, 42 out of 2256 published articles were included in this systematic review. In 21 articles, serum and milk samples were evaluated simultaneously with serological or molecular tests, and the results were compared. The results of descriptive studies and a review of nine experimental studies showed that milk could be used as a non-invasive and alternative sample for the serum in the diagnosis of toxoplasmosis.
Conclusion: Due to the relatively high prevalence of Toxoplasma gondii (T. gondii) infection in milk, consumption of raw milk from infected animals can be a potential source of human infection and a significant threat to public health. On the other hand, due to the ease and cheapness of collecting milk samples, the use of milk is recommended for the diagnosis of toxoplasmosis.
Iran's Health Transformation Plan; Main Issues and Opportuni-ties for Improvement: A Systematic Review
Authors: Ghasemyani Shabnam , Raoofi Samira , Hamidi Hadi , Khodayari-Zarnaq Rahim
Published: September 2022

Background: The Health Transformation Plan (HTP), as the latest reform of Iran's health system, has been implemented gradually in several phases to facilitate the achievement of universal health coverage. We aimed to identify the achievements and challenges of the HTP from the beginning of its implementation in Iran health system.
Methods: In this qualitative systematic review, English papers were searched in PubMed, Scopus, Web of science, and Google Scholar search engines in addition to Persian databases such as Magiran and SID from 2014-2020. The Mixed-Methods Appraisal Tool (MMAT) checklists were used to assess the quality of the studies. Study selection, quality assessment, data extraction, and data analysis were done independently by two people. For analyzing the data, the Framework Analysis Method, based on the health system function framework of the WHO, was used.
Results: Overall, 32 papers were included based on the inclusion criteria. The results were divided into four main themes: stewardship, financing, resource generation and service delivery, and20 sub-themes in the form of achievements and challenges. Regulatory and standardization, service packages, medical equipment and supplies, and the quality of health services were more repetitive. Considering the challenges of HTP, purchase process, motivational factors, and health services capacity were more repetitive.
Conclusion: The administrative challenges in the implementation of the HTP have prevented the sustainability of the outcomes and their main goals. The use of strategic dynamic planning, anticipating sustainable financial resources, and strengthening the monitoring mechanisms could lead to further achievements.
Factors Influencing Suicide Attempts of Adolescents with Suicidal Thoughts in South Korea: Using the 15th Korean Youth Risk Behavior Web-Based Survey (KYRBS)
Authors: Kwon Myoungjin , Kim Sun Ae , Seo Kawoun
Published: September 2022

Background: Adolescence is a period of physical and psychological change that causes adolescents to experience anxiety, stress, and loss of control. These experiences can lead to thoughts about suicide. However, not all adolescents with suicidal thoughts attempt suicide. This study aimed to identify the factors that influence suicide attempts among adolescents with suicidal thoughts, and to prepare a theoretical basis for a method to prevent suicide among adolescents.
Methods: In this descriptive cross-sectional study, the 15th Korean Youth Risk Behavior Web-Based Survey (2019) was used. The participants were 7,498 adolescents aged 12-18 yr with thoughts of suicide. Factors influencing suicide attempts among adolescents with suicidal thoughts were analyzed using a complex sample logistic analysis.
Results: Gender, age, academic performance, and economic level were the general factors associated with suicide attempts of adolescents with suicidal thoughts. Physical and psychological factors included smoking, alcohol use, drug use, sex-related experience, experiencing violence, efforts to reduce weight, level of physical activity, and depression.
Conclusion: Age and gender should be taken into consideration when designing suicide prevention activities. In addition, in order to lower the suicide rate of adolescents in Korea, an effective system of prevention and intervention strategies should be implemented, which attend to the issues of adolescents from low-income families, adolescent weight and body image concerns, and adolescent depression.
Diabetes Education in Children and Adolescents with Type 1 Diabetes in China
Authors: Chen Xiaochun , Dai Yangli , Zheng Yan , Yuan Ting , Dong Guanping , Wu Wei , Huang Ke , Yuan Jinna , Fu Junfen , Chen Xuefeng
Published: September 2022

Background: The prevalence of Type 1 Diabetes is increasing in pediatrics and diabetes education plays one of the most important role in the management of diabetes, especially in children. However, the related evidence concerned diabetes education is rare in children and adolescents. Therefore, we aimed to investigate the status of diabetes education in hospital, which could help us know the reality of diabetes education.
Methods: We choose a nurse who is mainly responsible for diabetes education and management in each hospital to fill out the questionnaire. Overall, 98 nurses were enrolled from tertiary children's specialized hospitals and pediatric wards of general tertiary hospitals from Jan 2018 to Dec 2019.
Results: Of 98 nurses enrolled, 61 (63.3%) nurses from 98 hospitals responded, 39 (63.9%) of them received specialized training in diabetes. There were no differences in education characteristics among regions of China. There were 26(42.6%) hospitals have a full-time nurse for diabetes education or nurses with endocrinology training increased with the number of cases/year (P=0.02 and P=0.009). The use of game-based education, knowledge assessment at discharge did not vary among hospital volumes, and the presence of a psychiatrist (P=0.41, P=0.65, and P=0.85, respectively). Diet management education is the most common (23.0%) difficulty in children diabetes education.
Conclusion: The level of diabetes education in children and adolescents varied among hospitals, but not among regions in China. There was a lack of resources provided for children and adolescents diabetes education in terms of training and specialized services.
A Psychological Nursing Intervention for Patients with Breast Cancer on Inflammatory factors, Negative emotions and Quality of Life
Authors: Li Mo , Xie Xianxin , Xu Hui , Li Hui
Published: September 2022

Background: We aimed to evaluate the effect of a psychological nursing intervention on inflammatory factors, negative emotions and quality of life in patients with breast cancer.
Methods: Patients at the Cancer Hospital of China Medical University from January 2017 to January 2020 were stratified into two groups based on the way of nursing. Patients in the control group received routine care, and the experimental group received appropriate psychological care interventions in addition to routine care. We compared the inflammatory factors (interleukin-6 (IL-6) and C reactive protein (CRP)), negative emotions (self-rating depression scale (SDS) and self-rating anxiety scale (SAS)) and quality of Life (short form-36 survey (SF-36)) between two groups.
Results: A total of 226 patients with breast cancer were enrolled in this study. Before the intervention, the CRP, IL-6, SAS and SDS between two groups were not significantly different (t=0.205, 0.971, 0.590, 1.579; P=0.838, 0.332, 0.556, 0.116). After the intervention, the CRP, IL-6, SAS and SDS between two groups were decreased and significantly different (t=-17.648, -18.079,-18.267,-18.613; P<0.05) 
Besides, the social function , physiological function, mental health, physical pain, physical limitation, vitality, emotional functions and overall health were improved and  significantly different between two groups after intervention (P<0.05).
Conclusion: A psychological nursing Intervention has the beneficial effect on the inflammatory factors, negative emotions and quality of life in patients with breast cancer.
Compound Homozygous Rare Mutations in PLCE1 and HPS1 Genes Associated with Autosomal Recessive Retinitis Pigmentosa in Pakistani Families
Authors: Babar Masroor Ellahi , Ali Akhtar , Abbas Syed Hassan , Hasnain Mirza Jawad Ul , Babar Nida , Babar Hira , Hussain Tanveer , Nadeem Asif , Ayub Namra , Shahid Sundus , Tariq Pervez Muhammad
Published: September 2022

Background: Retinitis pigmentosa (RP) belongs to pigmentary retinopathies, a generic name for all retinal dystrophies with a major phenotypical and genotypical variation, characterized by progressive reduction of photoreceptor functionality of the rod and cone. Global prevalence of RP is ~ 1/4000 and it can be inherited as autosomal dominant (adRP), autosomal recessive (arRP) or X- linked (xlRP). We designed this study to identify causative mutations in Pakistani families affected with arRP.
Methods: In 2019, we recruited two unrelated Pakistani consanguineous families affected with progressive vision loss and night blindness from Punjab region. Clinical diagnosis confirmed the; bone spicule pigmentation of the retina, and an altered electroretinogram (EGR) response. Proband and healthy individual from each family were subjected for whole-exome sequencing (WES).  Various computational tools were used to analyze the Next Generation Sequencing (NGS) data and to predict the pathogenicity of the identified mutations.
Results: WES data analysis highlighted two missense homozygous variants at position c.T1405A (p.S469T) in PLCE1 and c.T11C (p.V4A) in HPS1 genes in proband of both families. Healthy individuals of two families were tested negative for p.S469T and p.V4A mutations. The variant analysis study including molecular dynamic simulations predicted mutations as disease causing. 
Conclusion: Compound effect of mutations in rarely linked PLCE1 and HPS1 genes could also cause RP. This study highlights the potential application of WES for a rapid and precise molecular diagnosis for heterogeneous genetic diseases such as RP.
Epidemiological Characteristics of Hand, Foot and Mouth Disease Reinfection in Guangzhou, Southern China from 2012 to 2017
Authors: Zhong Xuan , Wang Hui , Chen Chun , Zou Xiaoni , Li Tiegang
Published: September 2022

Background: Hand, foot and mouth disease (HFMD) reinfection is common because of the limited cross-protection from infections of different enterovirus. We aimed to investigate the epidemiological characteristics and its influential factors of HFMD reinfection in Guangzhou, China.
Methods: Data on HFMD patients aged ≤5 yr from 2012 to 2017 were extracted from surveillance system. Influential factors of reinfection were assessed using the logistic regression model.
Results: Of 369,054 HFMD patients, 11,321 patients (3.07%) were classified as reinfection. The reinfection rate in male was higher than in female (χ2=60.11, P<0.001). The reinfection rate in patients ≤1 yr was 3.86%, which showed a downward trend with age (Z=37.37, Ptrend<0.001). The highest reinfection rate was observed in the scattered children (3.38%), followed by nursery care children and others (χ2=514.75, P<0.001). Besides, higher risk of reinfection was detected among those who were male, lower age group, rural residence and other enteroviruses infection compared with their respective counterparts. Seasonality was illustrated according to the number of reinfections peaked from April to July. Time intervals curves revealed the number of reinfections gradually increased after 13 months from the initial infection.
Conclusion: Male ≤4 yr, living rural area, especially those lived scattered and infected with other enteroviruses were more likely to be reinfection.
The Long-Term Associations of Objective and Subjective Health Status on Mortality
Authors: Jeon Moon-Ju , Kim Jae-Hyun , Bae Sung-Man
Published: September 2022

Background: The aim of this study was to reveal the longitudinal associations of health status (HS) and Self-rated Health (SRH) on mortality.
Methods: Data from the Korea Longitudinal Study of Ageing were used in this study. The baseline data (2006) included 10,239 participants. The Cox proportional hazard model was used to verify the hypothesis.
Results: The mortality was high when the health status was Bad and higher when the SRH was Bad. The HS‑Bad–SRH‑Bad group had the highest mortality. Middle-aged people with diseases had higher mortality than older people who perceived themselves as in Bad health. For older people, mortality was high for SRH‑Bad people of all health statuses.
Conclusion: The results predict a high rate of mortality for middle-aged and older people with a combination of HS‑Bad and SRH‑Bad, with SRH being relatively more influential in mortality
LncRNA LOC285758 Induced Non-Small Cell Lung Cancer Development through Up-Regulating CDK6 by Sponge Adsorption of miRNA-204
Authors: Yu Xiangtao , Liu Dianjun , Wang Lin , Wang Liguo
Published: September 2022

Background: Non-coding RNA played one pivotal role in NSCLC in terms of pathogenesis and progression. We aimed to determine the LncRNA, which can be one new potential target for NSCLC treatment and its possible mechanisms from Jan 2017 to Aug 2020.
Methods: Gene LOC285758, which produced new cells in tumor cellular system, was knocked out. Its specific effects were tested in terms of cellular phenotype. LOC285758 was chosen to target for miRNA as well as downstream mRNA targeted by miRNA, which verified the combination predicted before. Specific impacts brought from miRNA on NSCLC cells were examined. At last, dynamic impacts produced through miRNA and LOC285758 on mRNA expression and NSCLC cellular phenotype were examined.
Results: LOC285758 expression was up-regulated in tissues and cells from NSCLC. Knocking out gene LOC285758 could repress cellular survival and migration of A549 and H292 cells. miRNA-204 was repressed via LOC285758 targeting. miRNA-204 over-expressing repressed invasion ability of NSCLC cells and CDK6 targeted by miRNA-204. CDK6 knocking out suppressed survival and migration of NSCLC cells. The influence brought from gene LOC285758 knocking out could be reversed through suppressing miRNA-204, causing up-regulated CDK6 as well as LOC285758 expression in NSCLC tissues. miRNA-204 was negatively correlated with CDK6 as well as LOC285758, respectively. Nonetheless, CDK6 possessed the positive relationship with LOC285758.
Conclusion: An axis of lncRNA LOC285758/miRNA-204/CDK6 can modulate NSCLC cells in terms of migration as well as survival.
Evaluation of Our Rabies Prevention Practices: Is Our Approach Correct?
Authors: Yıldırım Arzu Altunçekiç , Doğan Ahmet , Kurt Celali , Çetinkol Yeliz
Published: September 2022

Background: Rabies disease is zoonotic disease-causing encephalitis and resulting in death. It is possible to prevent the disease with suitable prophylaxis approaches. This study examined the compliance of post-exposure prophylaxis approaches with the guidelines and the reasons for non-compliance in contact cases at risk of rabies.
Methods: This retrospective cross-sectional study includes patients who continued the vaccination program from 2014-2018 at the Ordu University Medical Faculty Hospital Rabies Vaccination Center in Ordu, Turkey. Cases were assessed in terms of sociodemographic features, previous rabies vaccination history, features of the contact with rabies risk, attendance duration after contact, and whether all stages of prophylaxis were completed after contact.
Results: Of the 748 cases attending the vaccination center, the age range was 1- 91 yr, with a mean age of 28.12 ± 21.60 yr. Of cases, 62.3% were male (n =466) and 37.7% were female (n =282). Of risky contact, 60% comprised stray animals. Of recorded cases, 55.2% displayed approaches compatible with guidelines. Among incompliant approaches, the most frequent was administering vaccines even though observation was sufficient. (n = 174, 52%).
Conclusion: Contact with risk of rabies may result in insufficient administration of the stages in prophylaxis after contact, or contrarily, mistaken administration based on acting with a sense of excessive safety. Stray dogs or domestic animals without sufficient vaccinations comprise a significant risk despite all efforts. In order to prevent risky contact, there is a need for the development of correct strategies and to ensure continuity of in-service training for health professionals.
Awareness and Knowledge of Statutory Health Law 1751 of 2015 among Patients in Colombia
Authors: Olivera Mario Javier , Alenxandra Fory Alenxandra Fory Johana
Published: September 2022

The Article Abstract is not available.
Importance of Injury Prevention and Management for Youth Handball Athletes
Authors: Lee Eunjae , Lim Seung-Taek , Cho Ji-Hoon
Published: September 2022

The Article Abstract is not available.
An Analysis of Korean University Students’ Smartphone Use Situation and Lateral Spinal and Pelvic Tilt Indicators for Posture Evaluation
Authors: Kim Sang Soo , Ju Sung Bum
Published: September 2022

The Article Abstract is not available.
Health Education About Self-Care Management for Type 2 Diabetes Mellitus Patients During the COVID-19 Pandemic: A Case Study in Nursing
Authors: Prasetyo Yoyok Bekti , Nur'afini Dhea Dwinda
Published: September 2022

Diabetes mellitus (DM) is a risk factor for COVID-19 and is a comorbid condition that can lead to death in these patients. Health education for DM patients needs to be done to prevent serious complications. This study aimed to describe nursing problems experienced by DM patients during the COVID-19 pandemic. This research used an exploratory case study method. The sample of this research was one case of a DM patient who was treated at home, recruited by purposive sampling. Data were collected through interviews, physical examination, environmental observation, and the Friedman’s family nursing assessment instrument. The implementation of health education about self-care management in DM patients during the COVID-19 pandemic made the family feel significantly informed and supported, so that the family started to be careful in carrying out activities during the pandemic that could endanger the patient’s health.
Keywords: health education, self-care management, diabetes mellitus, nursing, COVID-19
Medical Waste Management at the Muhammadiyah University General Hospital of Malang During the COVID-19 Pandemic
Authors: Nur Subchi Thontowi Djauhari , Syamsiah Anwar Jamilatus , Fajri Ro'di Nur , Maudu'ah Siti
Published: September 2022

Medical waste in hospitals increased during the COVID-19 pandemic. Medical waste management is very important and includes sorting, transporting, weighing, temporarily storing, and handing over waste to third parties. The Muhammadiyah University General Hospital of Malang (RSU UMM) is a referral hospital for COVID-19. This study aimed to evaluate medical waste management at the RSU UMM during the COVID-19 pandemic. This was an observational, retrospective and descriptive study that was conducted from March 2020 until July 2021. The secondary data were taken from the environmental health unit reports at RSU UMM. The collected data included weights of COVID-19 and non-COVID-19 medical waste. Over the study period, there were 1762 COVID-19 patients. The solid waste included disposable waste and personal protective equipment. The medical waste at RSU UMM during the COVID-19 pandemic was more substantial than before the pandemic. The different treatments of medical waste before and during the pandemic were classified by type, weight and frequency of transport. Over the 16 months, 46,649 kg of hospital waste was managed.
Keywords: medical waste, COVID-19, weight of waste
Relationship Between Knowledge and Behavior in Facing the COVID-19 Pandemic in a Rural Community
Authors: Masruroh Nur Lailatul , Novinda Sari Riyya , Kurnia Anggraini Dwi , Melizza Nur , Prasetyo Yoyok Bekti
Published: September 2022

The best way to prevent COVID-19 transmission is to be well-informed about the virus, its symptoms, and how it spreads. It is important to protect ourselves and others from infection by implementing health protocols. However, many people ignore the health protocols. This could be due to a lack of knowledge about this disease. The aim of this study was to determine the relationship between knowledge and community behavior in dealing with the COVID-19 pandemic. This was a descriptive study with a cross-sectional approach. The sample included 153 households in Manggisari Village, a rural area in Malang Regency, who were chosen by simple random sampling. Data analysis involved the Spearman Rank correlation test. The results showed that the community had a moderate level of knowledge (71.8%) with moderate risk behavior towards COVID-19 transmission (65.5%). There was a significant relationship between knowledge and community behavior in facing the pandemic (p = 0.02).
Keywords: knowledge, behavior, COVID-19 pandemic, rural comunity
Characteristics, Antioxidant Activity, and Sun Protection Factor of Black Pomegranate Peel Ethanolic Extract Hydrogel
Authors: Ermawati Dian
Published: September 2022

Solar UV radiation can inactivate the SARS-CoV-2 virus and indirectly accelerate the recovery rate of Covid-19 patients by converting pro-vitamin D3 in the skin into pre-vitamin D. On the other hand, prolonged exposure to UV radiation might be harmful to skin health, making it necessary to use sunscreen. Synthetic chemical sunscreens can have adverse side effects, and alternatives utilizing natural ingredients are needed. The peel of the black pomegranate has strong antioxidant properties and it also has the potential as a sunscreen by making it into a topical hydrogel preparation. The purpose of this study was to examine the characteristics, antioxidant activity, and sun protection factor (SPF) capacity of the ethanol extract of black pomegranate peel hydrogel preparations. Hydrogel was created containing black pomegranate peel ethanolic extract at concentrations of 0.5%, 1.0%, and 1.5%. Then, the characteristic properties were determined, the antioxidant power was examined using DPPH (2,2′-diphenyl-1-picrylhydrazyl radical) assay, and the SPF was investigated by the spectrophotometry method. The hydrogel containing extracts of 0.5%, 1.0%, and 1.5% had characteristics that fulfilled the specified requirements, having an inhibition percentage of 27.39%, 54.90%, and 83.91%, respectively, at the sample concentration of 600 ppm, and the SPF of this hydrogel was 2.67, 4.36, and 6.65, respectively. Therefore, according to the findings, hydrogel of black pomegranate peel ethanolic extract is good as a topical antioxidant but is less effective as SPF sunscreen.
Keywords: antioxidant, hydrogel, SPF, black pomegranate peel ethanolic extarct
Interaction Between Exercise and Sleep Quality Through Melatonin Synthesis: A Literature Review
Authors: Mashfufa Erma Wahyu , Prisca Marina Navy Sealsi Adinda , Sari Ranti Kurnia , Dwi Marta Ollyvia Freeska , Setyowati Lilis , Aini Nur , Alifatin Aini
Published: September 2022

Irregular exercise or insufficient physical activity may disrupt the biological clock and secretion of the melatonin hormone, which is important in sleep regulation. Regular exercise with a certain intensity and duration can help the body to increase melatonin production which can reduce sleep disorders. A search of full-text articles relevant to exercise and sleep quality was conducted in this literature review. We used four international databases: PubMed, PMC, Wiley Library, and ProQuest. We searched for articles published from 2017 to 2021. After screening the collected articles, only 12 articles were included. The articles were assessed using the JBI appraisal tools and the data were analyzed using descriptive methods. It was found that regular exercise at a certain intensity and duration affects the production of the melatonin hormone in humans. 6 out of the 12 articles revealed that melatonin levels changed in the study participants after doing exercise. Furthermore, 6 other articles mentioned that exercise had an impact on improving sleep quality.
Keywords: physical activity, exercise, sleep quality, melatonin hormone