bluuebunny/crossref_metadata_2025 huggingface dataset:
Kewajiban Notaris melakukan Pembacaan dan Penandatanganan Akta di Depan Semua Pihak secara Bersama-Sama
Authors: Putri Kerina Maulidya , Anwary Ichsan , Haiti Diana
Published: May 2022

Tujuan dilakukannya penelitian ini adalah untuk menganalisa mengenai kriteria prinsip kehati-hatian notaris selaku pejabat umum dalam melaksanakan tugasnya terutama dalam hal pembacaan dan penandatanganan akta serta menganalisa mengenai bentuk pertanggungjawaban bagi notaris yang dalam pembuatan aktanya tidak memenuhi ketentuan Pasal 16 ayat (1) huruf m Undang-Undang Jabatan Notaris. Dalam hal ini penelitian ini menggunakan jenis penelitian hukum normatif, penelitian ini bersifat preskriprif analitis yaitu penelitian yang bersifat secara alamiah dengan suatu metode yang bertujuan untuk mempelajari satu atau beberapa gejalan dengan jalan menganalisanya dan dengan mengadakan pemeriksaan yang mendalam terhadap fakta tersebut untuk kemudian mengusahakan suatu pemecahan masalah-masalah yang ditimbulkan oleh fakta tersebut. Hasil Penelitian Pertama: Kriteria prinsip kehati-hatian notaris selaku pejabat umum dalam melaksanakan tugasnya dalam pembacaan dan penandatanganan akta ialah pengenalan terhadap identitas penghadap, memverifikasi data subjek dan objek penghadap, memberikan tenggang waktu dalam proses pembuatan akta, bertindak hati-hati, cermat dan teliti notaris wajib memeriksa kata demi kata yang tertuang dalam akta untuk meminimalisir kesalahan dalam penulisan akta, memenuhi syarat formiil dan syarat materiil dari pembuatan akta notaris berdasarkan Undang-Undang Jabatan Notaris, Pembacaan, Penandatanganan dan pembubuhan cap jempol. Apabila notaris melaksanakan prinsip kehati-hatian dengan memenuhi, mentaati peraturan yang ada di dalam undang-undang, maka notaris akan mendapatkan perlindungan, perlindungan hukum diberikan kepada mereka yang mentaati aturan-aturan undang-undang. Kedua: Tanggung jawab notaris yang melakukan perbuatan melawan hukum dalam bidang perdata, sanksinya berupa penggantian biaya, ganti rugi, dan bunga akibat yang akan diterima Notaris atas tuntutan para penghadap jika akta yang bersangkutan hanya mempunyai kekuatan pembuktian sebagai akta di bawah tangan atau akta menjadi batal demi hokum. Tanggung jawab notaris yang melakukan perbuatan melawan hukum dalam bidang administrasi, sanksinya berupa teguran lisan, teguran tertulis, pemberhentian sementara, pemberhentian dengan hormat, sampai pemberhentian dengan tidak hormat. Sedangkan pertanggungjawaban dalam konteks kode etik profesi notaris berupa pemberian sanksi teguran, peringatan, pemecatan sementara (schorsing), pemecatan (onzetting) dan pemberhentian dengan tidak hormat dari keanggotaan perkumpulan. Dan, pertanggungjawaban secara pidana, Undang-Undang Jabatan Notaris tidak mengatur sanksi pidana untuk Notaris yang melanggar Undang-Undang Jabatan Notaris. Jika terjadi hal seperti itu maka terhadap Notaris tunduk kepada tindak pidana umum.
Pengaruh Stres Kerja, Lingkungan Kerja, Motivasi, Loyalitas Dan Kepemimpinan Terhadap Kinerja Perawat Di Era Covid19
Authors: Raya Yuni , Hendarwan Harimat
Published: May 2022

ABSTRAK

 

 

Kinerja  seorang  perawat  dapat dilihat   dari   mutu   asuhan   keperawatan   yang diberikan  kepada  pasien,  karena  pada  dasarnya yang dijadikan acuan dalam menilai kualitas pelayanan  keperawatan  adalah  dengan menggunakan standar praktik keperawatan. Tujuan penelitian untuk mengatahui pengaruh stres kerja, lingkungan kerja, motivasi, loyalitas dan kepemimpinan terhadap kinerja perawat di era covid19 perawat di  Rumah Sakit dr. Minthohardjo Jakarta Tahun 2020. Jenis penelitian ini adalah penelitian kuantitatif. Desain penelitian yang digunakan adalah cross-sectional. Sampel dalam penelitian ini menggunakan purposive sampling adalah sebanyak 103 responden. Berdasarkan hasil penelitian menunjukan ada pengaruh stres kerja (Pvalue 0.028 OR =< α (0.05), lingkungan kerja (Pvalue<= 0.005; OR  = 3.086), motivasi  (Pvalue<= 0.05; OR = 4.643), loyalitas (Pvalue<= 0.05; OR= 3.247), dan kepemimpinan (Pvalue<= 0.05; OR = 3.38) terhadap    perawat di Rumah Sakit dr Minthohardjo Jakarta Tahun 2020.Disarankan bagi Rumah Sakit dapat mengontrol kinerja pelayanan perawat agar terciptanya hubungan yang baik antara perawat dengan pasien serta meningkatkan kinerja untuk tujuan pelayanan kesehatan rumah sakit yang lebih baik serta melakukan tindakan inpeksi kerja kepada perawat dalam melakukan tindakan keperawatan.
Analysis of Compressive Strength of Sulfur Concrete
Authors: Romadhon Eri S. , Hanif Achmad
Published: May 2022

One of the best concrete mixes to reduce environmental impact is using sulfur concrete. The use of sulfur, as a waste material for enterprises, for the production of building materials is efficient due to the disposal of waste and its contribution to environmental protection. Sulfur concrete material has high compressive strength, low hydraulic conductivity, and high resistance to water permeation and is particularly resistant to corrosion in acid and salt environments. Sulfur concrete is more resistant to corrosion. Waterproofing reduces fatigue under repetitive load, develops strength very high start, fast hardens, saves time to manufacture, and holds to an aggressive environment. The aims of this study were 1) To determine the compressive strength of sulfur-bonded concrete with an aggregate ratio, 2) To determine the compressive strength of concrete based on the percentage of sulfur binding material from the combined aggregate weight and specific gravity of the concrete 3) To determine the strength of the sulfur-bonded concrete with a maximum age of 28 days. The research method used is an experimental method based on calculating the density of concrete specimens and the volume of the mould for sulfur concrete specimens. The results showed that 1) the best percentage of mixed material was aggregate fine and coarse 40%: 60%. 2) With use pro percentage sulfur 25%, 27.5%, 30%, 32.5%, 35%, 37.5% and 40% of heavy aggregate combined and weight type concrete 2400 kg/m3. 3) Research results obtained maximum strength sulfur concrete 28 days old of 429.5 kg/cm2 at 32.5% sulfur percentage and the lowest 250.5 kg/cm2 at the percentage of sulfur 25%.
Sosialisasi Pengenalan dan Penerapan Clean, Health, Safety dan Environmental Sustainability (CHSE) pada Masyarakat Desa Wisata Sukajadi, Kabupaten Bogor, Jawa Barat
Authors: Kusumawardhani Yuviani
Published: May 2022

Tourism development can stimulate an increase in the number of tourist visits to tourist destinations. The benefits and advantages of tourism development can be felt from an economic, socio-cultural and environmental perspective as well as an alternative to poverty alleviation. Tourism village is a tourism product with cultural value by considering carrying capacity factor. Tourist villages with the principle of carrying capacity are considered.  Tourist villages with the principle of carrying capacity are considered suitable to meet tourism needs during the pandemic. Sukajadi Village is one of the villages located in Bogor Regency. Sukajadi Village has natural potential and strong cultural elements. In addition to local uniqueness, tourist villages must be able to adapt quickly to global developments, especially during a pandemic like today. Tourism villages with the CHSE principle are able to accommodate health protocols so that tourists can feel safe when visiting. The Sukajadi Tourism Village community does not yet have the competence, knowledge, awareness, and motivation to go to a CHSE-based tourism village. Based on these facts, the socialization of the implementation of CHSE in the Sukajadi Tourism Village was given to the village community and Pokdarwis. The outcome of this activity is to increase the competence, knowledge, awareness, and motivation of the village community to jointly coordinate, integrate, and synchronize through a commitment to involvement, communication, and leadership in building a CHSE-based tourism
Microfinance program and food security: A Review in the Indonesian context
Authors: Purnawan Endar , Brunori Gianluca
Published: May 2022

This paper addresses the way microfinance programs affect food security, whic h is compiled based on a literature review of a total of 58 pieces of literature, from 1995 to 2020. Its paper sheds light on microfinance in rural areas in Indonesia, microfinance and food security, and critics related to microfinance programs based on a literature review. The result indicates that when the program’s impact on participants’ families’ food security and nutrition is measured, the results could be different. Most of the results stated a positive impact, but it might depend on many other factors. Taken together, the paper findings highlight the importance of a cycle of innovation, experimentation, and evaluation that must be carried out to build a robust financial institution to answer challenges and provide solutions to all the various conditions experienced by low-income families, involving various institutional structures, modes, and mechanisms. Other supporting factors are also important, including community involvement, the availability of safety nets, and non-financial support in many fields, such as increasing institutional capacity, business development, technology utilization, procurement, production, and, most importantly, marketing.
Detection of financial and non-financial factors affecting the acceptance of going concern opinion
Authors: Yanto, S.E., Ak., M.Ak. Ery , Monifa Stasya
Published: May 2022

Financial statements are source of information for investors in determining which companies to invest in. Therefore, the reliability of financial statements has an important role. In order for financial reports to be reliable, there are two important things, namely reporting quality and earning quality factors. The auditor gives a fair opinion as a form of reporting quality. Thus, the going concern opinion is one of the opinions given by the auditor on earning quality. This study tries to examine what factors encourage the auditor to give going concern opinion to the company. The method used is a quantitative method using inferential statistics. In particular, the instrument used is logistic regression. The findings of this study are that companies that tend to get a going concern opinion have certain characteristics, among others, are large companies that have profits and have a fairly high level of debt. This finding can then be used by investors to identify companies that have the potential to get a going concern opinion.

 
«Fuir la Shoah. Ma rencontre avec des témoins». Une application numérique pour enseigner la Shoah avec des témoignages audiovisuels
Authors: Fink Nadine , Masungi Nathalie
Published: May 2022

The educational application «Fleeing the Holocaust. My encounter with witnesses» enables a sensitive topic to be addressed in the classroom - the teaching of the genocide of European Jews - with the help of audiovisual testimonies. It gives access to the stories of five witnesses who tell, with courage and strength, of their lives overhelmed by the Holocaust and the way they were able to survive, to build themselves as individuals capable of keeping faith in life and in humanity. Aimed at young people from the age of 14, it is based on an innovative digital device that scripts the student’s learning path. In addition to a unique encounter between young people and witnesses, the application offers a series of tasks based on original documents that lead students to become familiar with the theme and to explore it in greater depth.
Inclure les femmes dans l’histoire enseignée. Quelles difficultés et remédiations pour la construction d’une séquence d’histoire mixte?
Authors: Bolay Morgane
Published: May 2022

This article examines the persistent inequalities in the representation of men and women in the history taught. Indeed, this discipline remains focused on a historical vision created by and for men. Based on this observation, it is a question of studying the possibilities of constructing sequences of mixed gender history, which take into account women as well as men in the historical narrative, which include gender history and deal with struggles leading to the acquisition of new rights. On the basis of an analysis grid presenting fundamental criteria related to this approach, different ways of remedying the imbalance found and the difficulties that could hinder it are identified.
Travail frontalier et développement transfrontalier au sein de la Grande Région Saar-Lor-Lux
Authors: Belkacem Rachid , Pigeron-Piroth Isabelle
Published: May 2022

Cet article s’intéresse aux effets du travail frontalier sur le développement économique et social des territoires situés au sein de la Grande Région Saar-Lor-Lux. Il montre que pour les territoires de résidence de ces travailleurs, le travail frontalier a permis d’amortir la crise économique locale à la suite des fermetures des usines et des mines. Pour les territoires d’emploi, il a constitué un facteur de développement économique en fournissant à la fois de la main d’œuvre et des compétences.
Avoir une place dans la « proximité urbaine ». Ethnographie d’un centre commercial
Authors: Besozzi Thibaut , Marchal Hervé
Published: May 2022

Partant de l’étude ethnographique d’un centre commercial situé dans le cœur d’une agglomération de l’Est de la France, nous montrons que des modes de vie de proximité s’y déploient et renferment des enjeux identitaires pour les personnes qui s’y inscrivent. La proximité urbaine, à la fois spatiale et sociale comme nous le verrons, peut être perçue comme un support de sens pour les « habitués » qui s’approprient l’espace intérieur du centre commercial et y développent les usages non conventionnels que sont l’appropriation de l’espace et l’entretien de relations de sociabilité primaires.
Les mises en ambiance de la ville apaisée Paradoxes et risques d’une aseptisation programmée
Authors: Thomas Rachel
Published: May 2022

En trente ans, l’engouement pour la marche en ville a nourri l’espoir d’un modèle d’urbanité plus apaisé. Cet article examine ce modèle, en portant plus particulièrement son attention sur le travail de mise en ambiance des espaces publics au Québec et en France. Après en avoir retracé les tendances fortes et exposé les critiques qu’il suscite, je m’interrogerai sur la façon dont il s’incarne dans le quotidien du piéton. À partir de deux exemples issus d’enquêtes de terrain menées à Montréal et à Grenoble, je qualifierai le paradoxe des ambiances de l’apaisement ainsi que les arts de se mouvoir et les impressions qu’elles dessinent.
Représentations plurielles de l’enseignement de la géographie au gymnase et comparaison des plans d’études à travers l’exemple de trois cantons romands
Authors: Bangerter Nicola
Published: May 2022

La Suisse, modèle du fédéralisme en Europe, accorde aux cantons une certaine autonomie en termes d’enseignements et de plans d’études appliqués dans leurs établissements du post-obligatoire en prenant soin de se baser sur des recommandations cadres. Cet article est basé sur un travail de mémoire professionnel qui part de ce constat pour tenter de mettre à jour les différences jalonnant les plans d’études de la géographie de trois cantons romands: Vaud, Berne et Neuchâtel. Un intérêt est également porté à l’influence de ces différences cantonales sur les discours qu’ont les enseignants de leurs pratiques au sein des écoles de maturité concernées.
DEVELOPMENT OF DAKON GAME INTERACTIVE E-BOOK MEDIA TO IMPROVE MATHEMATICS LEARNING OUTCOME OF ELEMENTARY SCHOOL STUDENTS
Authors: Maulidiyyah Aisyah , Nafiah Nafiah , Hartatik Sri , Rahayu Dewi Widiana
Published: May 2022

The low student learning outcomes in the concept of learning addition and subtraction in learning Mathematics, especially for grade 1 in Elementary School, is still not optimal. This is one of the contributing factors is the lack of mathematics learning materials developed by the teachers, and not many teachers involve students in the learning process so that students are less active in responding to the ongoing Mathematics learning. This study is intended to design learning media that can improve student learning outcomes in learning Mathematics through the development of interactive e-book media for the Dakon game. The formulation of this problem is how is the process of developing the Dakon Game Interactive E-Book Media to Improve Mathematics Learning Outcomes of Elementary School Students and How is the feasibility of developing Dakon Game Interactive E-Book Media to Improve Mathematics Learning Outcomes of Elementary School Students, this study uses the R&D development method only at level 1 with the stages of collecting potentials and problems, literature study and information gathering, product design, design validation, and tested design. With the results of the linguist validation test, the percentage of eligibility of 85% was declared very feasible to use, then the material validation test with a feasibility percentage of 83% was also declared very feasible to use, and the last one was the empirical scale test with a feasibility percentage of 86% indicating that the e-book media Dakon student interactive game is very feasible to use.
OVERVIEW SELF-EFFICACY AND SELF-ACCEPTANCE IN TUBERCULOSIS SUFFERERS
Authors: Setiyowati Eppy , Hardiyanti Hardiyanti , Setiawan Ferry Agus , Susilo Priyo
Published: May 2022

Background: Tuberculosis is still a major health problem in Indonesia, especially in the working area of the East Health Center in Surabaya, the long treatment of tuberculosis causes sufferers to have low self-efficacy and poor self-acceptance.
Objective: This study aims to analyze the relationship between self-efficacy and the self-acceptance of patients with Tb.
Method: The design research is an analytic study with a cross-sectional approach. The study population of 46 patients with active treatment for the last 3 months in the work area of the community Health Center in Surabaya by 46 patients.
Results: A sample of 41 respondents taken by simple random sampling technique. The independent variable is self-efficacy, the dependent variable is self-acceptance. The instrument uses a questionnaire. Data analysis used the Chi-Square test with significance value α = 0.05. The results showed that of 41 respondents the majority (57.3%) had low self-efficacy, and the majority (57.3%) had poor self-acceptance. Chi-Square statistical test results obtained value ρ = 0.008 < a = 0.05 shows there is a relationship of self-efficacy with self-acceptance of patients with TB in the work area of the East Perak Health Center in Surabaya.
Conclusions: Conclusions of the study that the lower the self-efficacy in patients with Tb the worse the self-acceptance and vice versa. Patients with TB should further improve their efficacy by always obeying health workers' advice and treatment regularly. The role of nurses in improving self-efficacy by providing education to sufferers and families, working together to care more, and motivate patients so that treatment success.
“Hacemos trabajar el dinero” (We Make the Money Work): Power among Ecuadorian migrant women in England who maintain transnational remittance management relations
Authors: Velasquez-Hoque Shirley
Published: May 2022

This study positions itself within the mixed results of remittances for migrant women’s empowerment, exploring the power dynamics of an under-researched diaspora - Ecuadorian migrant women in England who engage in transnational Remittance Management Relations (RMRs). Two contributions are made. First, embracing the Gender Geographies of Power framework, this paper argues that power needs to be conceptualised as a dynamic and multidimensional process, giving prominence to the various expressions, realms, and forms of power within these RMRs, dimensions which have not been previously emphasised in this framework. Second, findings suggest that remittances can have positive power implications for migrant women who engage in RMRs as they convert remittances into different forms of power (capital), gain various forms of power (including empowerment), and decision-making capabilities. However, RMRs are not always free of conflict. The mismanagement of remittances and/or the abuse of implementation power by remittance managers, can result in the loss of economic power for women remitters, and in changes to their remittance practices.
Wages in the Manufacturing Sector and Remittances Outflows from High-Income Countries
Authors: Gnangnon Sèna Kimm
Published: May 2022

This paper has investigated the effect of wages in the manufacturing sector on remittances outflows from High-Income Countries (HICs). The main theoretical hypothesis of the analysis is that changes in the wages in the manufacturing sector in HICs would affect wages in other sectors of the economy, and hence the amounts of remittances sent by migrants residing in these countries. The study has been performed on a set of 47 HICs, of which 22 old-industrialized countries, and uses both the fixed effects approach as well as the Least Squares Dummy Variables Corrected (LSDVC) estimator. Results have suggested for the full sample, that an increase in the real wages in the manufacturing sector is associated with higher remittances outflows. Interestingly, the magnitude of this positive effect is higher for remittances sent from old-industrialized countries than for remittances sent from other HICs. Moreover, the analysis has revealed that the magnitude of the positive remittances outflows effect of wages in the manufacturing sector increases as this sector expands, that is, as manufacturing export values increase. An important implication of the analysis is that by lowering wages both in the manufacturing sector and in other sectors of the economy, the shrinking of the manufacturing sector in HICs is likely to reduce the income of migrants residing in these countries and consequently lead to lower remittances outflows. The decline in the remittances outflows would severely affect the ability of receiving countries (i.e., developing countries) to tap on this important source of financial flows to finance their development.
Impact of Covid-19 pandemic on Remittance Inflow-Economic Growth Nexus in India: Lessons from an Asymmetric Analysis
Authors: Makun Keshmeer , Jayaraman TK
Published: May 2022

The relentless spread of the Covid-19 pandemic from the first quarter of 2020 and the emergence of new variants since early 2021 have caused a steep decline in economic activities in all countries. The forecast by international agencies including World Bank is that remittances (REM) on a global scale would decline by 20 percent in 2021; and to South Asia in particular would decrease by 25 percent. India, a low-middle-income country, which has been among the top ten REM recipient countries, is expected to be adversely affected much more. This study examines the asymmetric effects of REM on India’s per capita GDP by using a nonlinear methodology. Additionally, factors like ICT and the financial sector are considered in an extended version of the remittance-growth relationship. The study findings reveal that the impact of the negative partial sum of decomposition of REM is higher than the impact of positive partial sum decomposition of REM, implying a greater adverse effect of declining remittances on per capita GDP growth. The findings are expected to be of substantial importance in designing appropriate policies that affect economic growth through the interaction of remittances with ICT, and financial markets.
Is vulvar purpura a component of plasma cell vulvitis or mucosal porosis?
Authors: KAVAK Ayşe , SAKIZ Damlanur , YILMAZ Murat , GÜNAY Nimet Yeşim , YAŞAR Levent
Published: May 2022

Here, we presented six women with isolated vulvar purpura. No associated lesions such as sclerosis, atrophy, or hypopigmentation were observed. All patients were in postmenopausal period. In this case series, we discussed if a non-blanching purpura could be a component of plasma cell vulvitis or “mucosal porosis”. The possibility of vulvar purpura was questioned as a mucosal equivalent of dermatoporosis which is an age-related degenerative process in the skin. While senile purpura is one of the morphological findings of dermatoporosis, vulvar purpura might be a part of “mucosal porosis”. Rapid response to topical estrogen was remarkable in all patients.
Severe bullous pemphigoid after Vaxzevria COVID-19 vaccination
Authors: COWAN Timothy , WALLMAN Lucinda , MURRELL Dedee
Published: May 2022

Bullous pemphigoid has been described in a small number of cases secondary to the Pfizer and Moderna COVID-19 vaccinations. This is the first reported case of bullous pemphigoid triggered by the Oxford-AstraZeneca Vaxzevria COVID-19 vaccination. His first symptoms occurred four weeks after his first dose, and were confirmed on direct immunofluorescence and with positive BP180 antibodies.
APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis
Authors: Stritt Simon , Nurden Paquita , Nurden Alan T. , Schved Jean-François , Bordet Jean-Claude , Roux Maguelonne , Alessi Marie-Christine , Trégouët David-Alexandre , Mäkinen Taija , Giansily-Blaizot Muriel
Published: May 2022

Vascular homeostasis is impaired in various diseases thereby contributing to the progression of their underlying pathologies. The endothelial immediate early gene Apolipoprotein L domain-containing 1 (APOLD1) helps to regulate endothelial function. However, its precise role in endothelial cell biology remains unclear. We have localized APOLD1 to endothelial cell contacts and to Weibel-Palade bodies (WPB) where it associates with von Willebrand factor (VWF) tubules. Silencing of APOLD1 in primary human endothelial cells disrupted the cell junction-cytoskeletal interface, thereby altering endothelial permeability accompanied by spontaneous release of WPB contents. This resulted in an increased presence of WPB cargoes, notably VWF and angiopoietin-2 in the extracellular medium. Autophagy flux, previously recognized as an essential mechanism for the regulated release of WPB, was impaired in the absence of APOLD1. In addition, we report APOLD1 as a candidate gene for a novel inherited bleeding disorder across three generations of a large family in which an atypical bleeding diathesis was associated with episodic impaired microcirculation. A dominant heterozygous nonsense APOLD1:p.R49* variant segregated to affected family members. Compromised vascular integrity resulting from an excess of plasma angiopoietin-2, and locally impaired availability of VWF may explain the unusual clinical profile of APOLD1:p.R49* patients. In summary, our findings identify APOLD1 as an important regulator of vascular homeostasis and raise the need to consider testing of endothelial cell function in patients with inherited bleeding disorders without apparent platelet or coagulation defects.
Microbial quality evaluation of fresh vegetables from distinct markets in urban areas of Bangladesh
Authors: Ohiduzzaman  , Islam SM Akramul , Arif Mohammad , Saddam Md Jahidul Islam , Hossain Muhammad Tofazzal , Kabir SM Lutful , Uddain Jasim
Published: May 2022

This study was carried out from January to May 2018 to isolate, identify, and determine microbial loads (E. coli; Salmonella spp.; Staphylococcus aureus; Campylobacter spp.) in fresh-marketed vegetables sold at several marketplaces in the districts of Netrokona, Kishoregonj, and Jamalpur. In this study, 126 samples were collected, 90 of which were unique (tomatoes 18, carrot 18, cucumber 18, coriander leaf 18, green chili 18) and 36 of which were composite (made by combining the individual samples). The spread plate dilution method was utilized for this work, and the organisms were cultivated on selected culture media. Microbes that were expected were discovered utilizing culture and staining procedures. The number of Salmonella, E. coli, S. aureus and Campylobacter was found from all tomato (100%), cucumber (100%) and green chili (100%). In carrot samples, the number (%) of E. coli, S. aureus and Campylobacter was found 100% except Salmonella (88.88%). The number of Salmonella (77.77%), E. coli (100%), S. aureus (94.44%) and Campylobacter (100%) was found in coriander leaf. In conclusion, the high bacterial load and presence of these organisms, particularly Escherichia coli, Campylobacter spp., Salmonella spp., and Staphylococcus aureus, in salad vegetable samples could serve as an indicator of the need to raise awareness about the potential health hazards caused by improper handling of these vegetables.
Asian Australas. J. Food Saf. Secur. 2022, 6 (1), 1-9
Modulation of Rage and CD147 in Cerebral Amyloid Angiopathy in vitro
Authors: Mosiagina A. I. , Boytsova E. B. , Khilazheva E. D. , Teplyashina E. A. , Morgun A. V. , Salmina A. B.
Published: May 2022

Introduction. In the study of Alzheimer’s disease (AD), the cause-and-effect relationship between neurodegenerative changes and the accompanying amyloid angiopathy is becoming increasingly important. The accumulated clinical data indicates that an important contribution to the pathogenesis of AD is made by neurovascular unit dysfunction, including disruption in permeability of the blood-brain barrier (BBB), microcirculation, and metabolic coupling of cells.

Aim. To study the molecular mechanisms of disturbed brain microcirculation and the structural and functional integrity of the BBB in experimental models of AD in vitro under the modulation of CD147 and RAGE.

Materials and methods. The study was carried out on C57BL/6 mice. First, we formed an AD model in animals of the experimental group. Then, we isolated and cultured primary cells of the brain, modulated the activity of CD147 and RAGE in endothelial cells using siRNA CD147, siRNA RAGE, cyclophilin A and Aβ1-42, and formed a BBB model in vitro. Further, we assessed transendothelial electrical resistance in the BBB model in vitro, registered the marker molecules of angiogenesis and analyzed the expression of APP in endothelial cells. Statistical processing of the obtained data was carried out using the methods of nonparametric statistics: the Mann – Whitney U test for comparing independent samples and the Wilcoxon test for comparing dependent samples. The level of statistical significance of differences was p ≤ 0.05.

Results and discussion. Knockdown of RAGE led to a statistically significant increase in TEER, an intensification of neoangiogenesis, and a decrease in the level of APP expression. At the same time, although CD147 knockdown led to an increase in TEER, it also led to controversial effects on angiogenesis and an increase in APP expression.

Conclusion. Analyzing the data obtained, it can be concluded that RAGE and CD147 silencing in the cells of cerebral microvessels can become a promising method for reducing their pathological permeability.
Erken çocukluk dönemine yönelik fen temalı bilgi veren resimli çocuk kitaplarının incelenmesi
Authors: GÜNŞEN Gülşah , UYANIK Gülden
Published: May 2022

Fen temalı bilgi veren resimli çocuk kitaplarının çocukların fen kavramlarını doğru tanıma ve öğrenme, bilimsel kelime dağarcığını geliştirme ve en önemlisi de merak duygularını tetiklemesinde önemli katkıları bulunmaktadır. Bu noktada fen temalı bilgi veren resimli çocuk kitaplarının hazırlanma süreçlerinde fiziksel özelliklerinin yanı sıra çocukların gelişim seviyelerine uygun anlaşılır bir dille yazılması, uygun resimlemelerin yapılması gibi içerik özellikleri de önem arz etmektedir. Bu noktadan hareketle yapılan bu araştırmanın amacı erken çocukluk dönemine yönelik olarak hazırlanmış fen temalı bilgi veren resimli çocuk kitaplarının fiziksel açıdan, bilim resimlemesi açısından, fen içerik standart alanları açısından, yazım, doğruluk ve içerik özellikleri açısından incelenmesidir. Araştırma betimsel araştırma türlerinden tarama modeline uygun şekilde gerçekleştirilmiştir. Araştırma kapsamına dahil edilen kitapların seçiminde Türkiye’de okul öncesi öğretmenlerinin ve okul öncesi dönem çocuklarının ailelerinin kolaylıkla ulaşabileceği yayınlar olmasına ve fen temalı bilgi veren resimli çocuk kitaplarına yönelik en fazla yayına sahip yayınevi olması kriterlerine dikkat edilmiştir. Bu kriterler doğrultusunda TUBİTAK yayınlarının okul öncesi döneme yönelik olarak hazırlamış olduğu 118 fen temalı bilgi veren resimli çocuk kitabı araştırmanın çalışma grubunu oluşturmaktadır. Veri toplama aracı olarak araştırmacılar tarafından ulusal ve uluslararası alan yazın incelenerek hazırlanan ve uzman görüşü alınarak son hali verilmiş bulunan Fen Temalı Bilgi Veren Resimli Çocuk Kitaplarını İnceleme Kriterleri Formu ile incelenmiştir. Elde edilen bulgular doğrultusunda kitaplarda içerik açısından önerilerde bulunulmuştur.
Türkiye'de okul öncesinde kodlama eğitimine ilişkin yapılan çalışmaların incelenmesi
Authors: ZURNACI Burcu , TURAN Zeynep
Published: May 2022

Bu çalışmanın amacı, okul öncesi dönemde kodlama eğitimine ilişkin Türkiye’de yapılan bilimsel çalışmaların sistematik inceleme yöntemi ile incelenerek, konu ile ilgili araştırmaların yöntemsel eğilimlerinin, konularının, incelenen değişkenlerinin ve temel bulgularının ortaya çıkarılmasıdır. Bu doğrultuda, YÖK Tez Merkezi, TR Dizin ve Google Akademik veri tabanları üzerinde yapılan aramalar sonucunda belirlenen 30 çalışma (14 Tez, 14 Makale ve 2 Konferans Bildirisi), içerik analizi yöntemi ile analiz edilmiştir. Çalışma sonucunda, okul öncesi dönemde kodlama eğitimine ilişkin Türkiye’de yapılan çalışma sayısında istenen düzeyde olmasa da son yıllarda artış olduğu tespit edilmiştir. İncelenen çalışmalarda en çok nitel ve nicel araştırma desenlerinin kullanıldığı ve örneklem grubu olarak genellikle 5-6 yaş arasındaki okul öncesi öğrencilerinin seçildiği belirlenmiştir. İncelenen çalışmaların, çoğunlukla sınıf ortamında, kodlama derslerinde ve 8 ile 10 hafta arasında süren uygulamalarla gerçekleştirildiği tespit edilmiştir. Ayrıca çalışmalarda kodlama eğitimi ile genellikle algoritma tasarımı, sıralama, döngü, komut ve koşul gibi kodlama sürecinin temel kavramlarının öğretildiği görülmüştür. Bunlara ek olarak, çalışmalarda en çok problem çözme becerisi değişkeninin araştırıldığı ve sıklıkla bilgisayarsız kodlama etkinliklerinin kullanıldığı tespit edilmiştir. Ayrıca, robotik kodlamada en çok Bee-Bot aracının, blok tabanlı kodlamada ise en çok code.org platformunun kullanıldığı belirlenmiştir. İncelenen çalışmalar sonucunda, okul öncesi dönemde kodlama eğitiminin en sık belirtilen avantajının öğrencilere problem çözme becerisinin kazandırılması, en sık belirtilen zorluğunun ise döngü yapıları konusunun öğrencilerin anlamakta zorluk yaşamaları olduğu tespit edilmiştir. Son olarak sistematik incelemeden elde edilen bulgular doğrultusunda uygulayıcılara ve araştırmacılara yönelik çeşitli öneriler sunulmuştur.
The difficult clinical diagnosis of erythropoietic protoporphyria
Authors: Wahlin S , Floderus Y , Ros A-M , Broomé U , Harper P
Published: May 2022

We give a short survey of the Swedish erythropoietic protoporphyria patients (EPP) with respect to the lapsed time between symptom debut and diagnosis. With two examples we illustrate the consequence of undiagnosed EPP for the patient and also the family. We recall efforts to spread information among health workers in order to investigate patients suffering from extreme sun-exposure intolerance for this uncommon kind of porphyria as well.
Pilates Exercise Impact on Functional Movements, Core Stability and Risk of Injuries in Handball Players
Authors: Šniurevičienė Veronika , Baumann Laura , Žlibinaitė Laura
Published: May 2022

Background. Handball is a dynamic and physically demanding sport, especially due to the excessive contact of players during the game. The high velocity of the game, high number of matches and the athletic conditioning puts a strain on the musculoskeletal system, leading to a high risk of injury. Prior research substantiates the belief that a better spinal stabilization function due to the application of Pilates exercises would help to achieve better sports results and reduce the risk of injuries.

The aim. To evaluate the impact of a Pilates exercise program on functional movements, core stability and risk of injuries in young handball players.

Methods. 12 professional handball players aged 18.25 ± 0.45 years participated in the study. A Pilates exercise program was applied in addition to the regular handball training. The program lasted for 8 weeks, with the sessions organized on-line, twice a week for 60 minutes. Before and after the program, functional movements were assessed using the Functional Movement Screen (FMS) method, core stability was assessed by McGill core muscle isometric endurance tests, dynamic stability and associated injury risk was assessed by modified star excursion balance test.

Results. After the application of the Pilates exercise program, the evaluation of functional movements according to FMS scores significantly improved (p < 0.05). The isometric endurance ratio of the right and left side core muscles significantly improved (p < 0.05), and the isometric strength endurance ratio between the right side and back muscles also improved (p < 0.05). No significant change in either the total index of dynamic stability of the arms or legs, which indicates the risk of injury was found after the Pilates exercise program.

Conclusion. This study illustrates the idea that a Pilates exercise program improved quality of the handball players’ functional movements and the isometric strength of some core-stabilizing muscles, while the risk of injuries did not change.

Keywords: movement quality, static endurance, dynamic stability, athletes, core stabilization exercise.
Effect of “IPPON” and “Judo 9+” Interventions on Balance and Coordination in Young Judo Athletes
Authors: Naudžiūnaitė Eglė , Aleknavičiūtė-Ablonskė Vaida , Bubelis Justinas
Published: May 2022

Background. One of the most important skills for judo players is coordination. In judo it is standard to focus more on strength and endurance rather than coordination. Recently coordination of judo players has become a popular topic, and the importance of coordination development has been introduced to researchers. There is a lack of research about the effect of coordination training on balance and coordination changes in judo athletes.

The aim. To determine the effect of “IPPON intervention” and “Judo 9+” intervention on balance and coordination.

Methods. Seven (5 boys, 2 girls) judo athletes aged 13.5±1.6 yrs., height 1.6±0.13 m, weighs 57.6±14.6 kg with training experience exceeding 9 months (3.7±2.4 years) were recruited for the intervention. A coordination training program formed out of two programs (“IPPON” intervention and “Judo 9+”) was applied for 4 weeks. Static and dynamic balance, coordination of athletes was tested before and after the intervention.

Results. Statistically significant differences in coordination, static and dynamic balance of judo athletes were not found after 4 weeks of coordination training. While comparing test results before and after coordination training, we found increases (p > 0.05) of posterolateral reach in right leg (4.14 cm), anterior (0.71 cm) and posteromedial (1.14 cm) reach in left leg in a modified star excursion test, an improvement was found in the Harre coordination test (0.72 s).

Conclusion. The four-week IPPON intervention and Judo 9+ exercise program was too short to significantly improve the coordination and dynamic balance of the judo sport.

Keywords: static balance, dynamic balance, coordination
CONFUCIUS INSTITUTE IN ST PETERSBURGAS A SOFT POWER TOOL IN THE CONTEXT OF THE “ONE BELT, ONE ROAD” INITIATIVE
Authors:   St. Petersburg State University, St. Petersburg, Russian Federation, CHANG QU
Published: May 2022

In today’s world, the process of global economic integration has accelerated, and the integration of the world’s countries in the political, economic and cultural fields has further deepened. Language is not only a tool of communication that allows countries to understand each other, but also an important component of national “soft power”. Today, “soft power” is increasingly included in the foreign policy strategies of states, which has a positive impact on their internal development and contributes to the spread of their influence on other countries. As the Chinese language and culture become more and more popular abroad, interest in the Chinese language is growing among Russians as well. The promotion of Chinese culture and language in St. Petersburg, Russia’s second largest city and the center of the western part of the country, is especially important. The Confucius Institute in St. Petersburg was chosen for this work. Based on a theoretical analysis of the concept of soft power, the article begins with the Confucius Institute as a tool for developing soft power. It analyzes the opportunities and challenges facing the Confucius Institute in St. Petersburg through case method, comparative analysis, and literature search, and then suggests countermeasures for the Confucius Institute’s intercultural communication in countries along the “One Belt, One Road”. From this the author concludes that the success of the Confucius Institute in St. Petersburg is inseparable from the political, economic and cultural support of Russia and China, but its development is also accompanied by problems in systems and politics.
CONSTRUCTION OF THE EURASIAN SYMBOLIC SYSTEM IN THE CONTEXT OF DISINTEGRATION/INTEGRATION AND DISCONNECTION/CONNECTION WITH THE SOVIET SYMBOLS
Authors:   Financial University under the Government of the Russian Federation, Moscow, Russian Federation, TEN JULIA
Published: May 2022

The author offers the symbolic approach to understanding the nature of the construction of the Eurasian identity in the framework of the EAEU as the result of (dis-)integration and (dis-)connection with the Soviet symbols. The goal of the research is to provide the interdisciplinary analysis of shaping the EAEU’s symbolic identity. The symbolic and dialectic approaches are used. The main idea consists in the suggestion that the symbols are social technology of creating EAEU’s identity. The article argues that EAEU’s symbolic system is shaping on the logic of (dis-)connection and (dis)integration with the meanings of the symbolic system of the USSR. The dialectic logic of integration and connection means greater interaction of Belarus, Kazakhstan, Kyrgyzstan, Armenia and Russia. A logic of history of integration and connection is determined on the attempt to revive the Soviet symbols which can be the basis for the construction of common symbolic system. The inner strength of such integrative process lies in the fact that the new phenomenon of the EAEU is not seeking the reincarnation of the old symbols of the Soviet era, serving the expression of utopian ideas. The key findings of the research can be the basis for the practical recommendations in terms of the Eurasian cultural policy.
HUMANITARIAN KNOWLEDGE AT THE ENTREPRENEURIAL UNIVERSITY: STRATEGIES OF «JUSTIFICATION»
Authors:   Belgorod State Technological University named after V.G. Shukhov, Belgorod, Russian Federation, BINKOVSKAYA LARISA , MALTSEV KONSTANTIN , MALTSEVA ANNA
Published: May 2022

Humanitarian knowledge and “liberal education” have been a problem for the modern innovative/entrepreneurial university as a commercial firm for the last fifty years: “impact” as an imperative of the university’s public discourse in liberal democracies and university policy apparently contradicts the statements about the “self-worth” or “uselessness” of humanitarian knowledge. The purpose of the article is to consider the main directions of the “justification” of the “humanitarian component” of the university, the ways of its politicization (the term U. Beck): appeals to values (culture), to the public good, civic education, to the methodological function of philosophy and the humanities, undertaken in this regard. The absence of grounds for the above-mentioned methods of politicization to matter is demonstrated: both in connection with their own inconsistency of such values, and as an argument for the prevailing public discourse of the university. It is concluded that the prevailing liberal interpretation of humanitarian knowledge necessarily provides for its transformation into a product whose price is determined by the market. The actual “problem situation” is not related to the “nature of humanitarian knowledge”, but to the “struggle for status”, that is, it is a question of power and prestige in connection with their redistribution in an entrepreneurial university as a commercial company.
TRANSFORMATION OF THE POLITICAL REGIME IN KAZAKHSTAN
Authors:   Financial University under the Government of the Russian Federation, Moscow, Russian Federation, OKUMBEKOV RINAT
Published: May 2022

The purpose of the article is to study the topic problem of the power political transit. The main components of the neopatrimonial regime are highlighted, the analysis of some legislative acts and initiatives of the President, as well as the Dossier on the draft Constitutional Law of the Republic of Kazakhstan “On introducing amendments and additions to some constitutional laws of the Republic of Kazakhstan”. As a result of which, by comparing the main components of the neopatrimonial regime on the one hand, and the legislative initiatives of the President on the other hand, the basis for the rejection of neopatrimonial practices in Kazakhstan was revealed. The conditions for the transformation of its post-crisis democratic development are formulated and substantiated. This article is a continuation of the previous research devoted to the analysis of political transformations in the transitional period of the Republic of Kazakhstan (Voprosy politologii. 2022. Vol. 12. № 2 (78)), in which, within the framework of the transformation theory of political regimes the process of neopatrimonial regime transition to democracy is considered.