bluuebunny/crossref_metadata_2025 huggingface dataset:
THE PRESENCE OF COLLABORATION SKILL IN ELT CLASS
Authors: Sudinpreeda Hakim , Mutohhar Mutohhar , Nurcahyo Agung Dwi , Kartika Fajar
Published: December 2020

One of the skills that must be possessed in the 21st century is collaboration skill. It requires teachers to present or provide it in the learning process, so that later students are expected to be able to implement it in their real life. The study reported in this paper aims to describe the implementation of collaboration skill in the process of teaching and learning. The data collected by means of close-ended questionnaires and guided interview that were administered to 125 freshman students of the English Education Department of Universitas Muria Kudus. The result shows that 84% of the students said that the teacher has implemented the collaboration skill, however from 84%, only 48% is categorized as instructionally effective. It is suggested that the teachers should manage some instructions and control how the instructions are executed. Keywords: 21st century skills, collaboration skill, effective instruction.
THE USE OF SOCIAL MEDIA FOR LEARNING ENGLISH
Authors: Handayani Rahmawati Dwi , Syafei Muh , Utari Aisyah Ririn Perwikasih
Published: December 2020

abstract. The objective of the research is to find out the kinds of social media used by fourth semester students of English Education Department of Universitas Muria Kudus for learning English. The researchers used descriptive qualitative research and the data was collected by the use of questionnaire. The participants are 50 students of English Education Department of Universitas Muria Kudus. The result showed that social media the students use for learning English are YouTube (94%),, Instagram (72%0, WhatsApp (62%), Twitter (32), Facebook (30%), Line (10%), Manwha (6%), Telegram  (2%), Google (2%),  Tik Tok (1%), Cake English App  (1%), Quora (1%) and Discord (1%)
What is the diagnosis?
Authors: Birdal Oğuzhan , Koza Yavuzer , Altınkaya Onur , Taş Hakan
Published: December 2020

Paced right bundle branch block pattern in an elderly woman
Epistemologias marginais: Ciências da Religião em perspectiva descolonizadora e intercultural | Marginal epistemologies: Science of Religion in a decolonizing and intercultural perspective
Authors: Borges Ângela Cristina , Senra Flávio
Published: December 2020

Qual o lugar das epistemologias marginais e das teorias interseccionais na Ciências da Religião? Para responder a essa questão, o presente artigo se estrutura em três partes. A primeira traz a concepção de epistemologia marginal, ressaltando sua característica principal, a saber, a crítica ao monismo epistemológico ocidental. Na segunda parte, apresentam-se duas formulações teóricas que, a despeito de suas diferenças, propõem o diálogo intercultural como ferramenta teórica e prática que pode, enquanto subversão ao Sistema Mundial Moderno, fazer sucumbirem estruturas hierárquicas entre regiões, populações e culturas no planeta, na medida em que são propostas políticas e éticas frente aos desafios mencionados. Uma e outra reconhecem a necessidade de novas lógicas para se pensar o mundo, bem como trazer à tona lógicas anteriores à modernidade, a exemplo das narrativas religiosas. Por fim, na terceira parte, o artigo apresenta o culto aos orixás, especificamente no Candomblé, com o propósito de demonstrar que religiões marginais, constituídas de elementos culturais pré-modernos, podem ser descolonizadoras, porquanto atuam como agentes do diálogo intercultural. Aqui se revela uma perspectiva para a Ciências da Religião à luz das epistemologias marginais. Em rituais afrorreligiosos, corpos ritmados em som e palavra cantada encarnam elementos culturais anteriores à modernidade.
Russian organizations social capital formation external factors
Authors: Igumnov O. A.
Published: December 2020

The scientific approach presented in this article is based on the understandingof social capital and corporate culture as intersecting organizational phenomenahowever irreducible to each other. At the same time corporate culture is understoodinstrumentally and it is considered as a factor in the social capital formation, development and using process mediating its organizational and managerial effects. This doesnot negate the fact of complex iterative relations between them but allows to place theemphasis correctly both theoretical and practical, emphasizing the more fundamentaland comprehensive nature of social capital directly arising from the laws of socialinteraction and developing regardless of the purposeful management efforts to form asingle corporate culture.The analysis of various studies of social capital in Russia and abroad characterizingthe level of generalized trust in Russia as low and noting the multidirectional dynamicsbetween different types of social capital which are not typical for developed countries.These differences are interpreted in terms of differences in social relations types underlyingsocial capital: affiliation, hierarchy and exchange. From this point of view the high levelof declared institutional trust (with a certain degree of assumption) can be interpreted asa manifestation of the rational (“calculation”) mechanism of social capital constructionin modern Russian society. The conclusion about insufficient account in foreign scientistsof social, cultural and spiritual components researches is made.The analysis of the problems that have a negative impact on modern Russian societyin the process of social capital formation at the micro, meso- and macrolevels is made.The main problems are the lack of social unity and the spread of the Russian version ofindividualism associated with severe problems of survival and increasing the level ofinterpersonal and institutional distrust.
AI334, AQ806, AR222, AR249, AS274, AS708, RB572, RB574 and RB596 antibodies recognize SARS-CoV-2 viral particles by dot blot
Authors: Lacombe Jerome , Zenhausern Frederic , Cosson Pierre
Published: December 2020

The recombinant antibodies AI334, AQ806, AR222, AR249, AS274, AS708, RB572, RB574 and RB596 detect inactivated SARS-CoV-2 viral particles by dot blot.
Percepção dos estudantes em relação à sala de aula invertida
Authors: Jeffman dos Santos Mirela
Published: December 2020

O presente estudo teve por objetivo analisar a percepção dos estudantes do ensino superior em relação ao seu processo de aprendizagem e aos procedimentos pedagógicos adotados em uma proposta de sala de aula invertida. A motivação para esse estudo surgiu a partir da necessidade de repensar o formato tradicional da aula, que prioriza a exposição de conteúdos, especialmente na era digital. A sala de aula invertida propõe que as atividades anteriormente desenvolvidas em casa sejam realizadas em aula e vice versa, isto é, o estudante se apropria do conteúdo em casa e comparece à aula para debater, experienciar e esclarecer dúvidas sobre o conteúdo. Esse estudo foi conduzido por meio de uma abordagem quantitativa com 142 estudantes de disciplinas do curso de administração em uma universidade do sul do país, que foram expostos a procedimentos de sala de aula invertida em, pelo menos, um momento do semestre letivo. Os resultados revelaram a percepção favorável dos estudantes em relação ao seu aprendizado, aos materiais utilizados, às tarefas propostas e aos professores; demonstrando que o seu aprendizado nessas disciplinas foi significativo, que a realização de atividades práticas contribuiu para o seu conhecimento e que o papel do professor foi fundamental nesse processo.
Policy on the Development of Doctor's Functional Officials in the State Civil Apparatus Against Violation of the Doctor's Code of Ethics
Authors: Apriyanto Apriyanto
Published: December 2020

A doctor of the State Civil Apparatus (ASN) in the implementation of medical practice has the potential to be subject to ethical sanctions by his professional organization in the form of a recommendation to revoke the Practice License which causes loss of authority to practice. Based on this, the loss of authority will at least raise the question of whether losing the authority to carry out the medical profession will have implications for his functional position as an ASN doctor and what is the coaching policy as an ASN doctor functional official in relation to violations of doctor ethics. The research was conducted with a statue approach and a case approach. The result of the research is that the loss of formal authority due to ethical violations does not have implications for the functional position of doctors and the guidance carried out by ASN doctors who have been sanctioned for ethical violations in the form of re-competency tests, transfers, and dismissals. Suggestions are needed by laws and regulations that explain the stipulative meaning of the relationship between ethical violations and the application of disciplinary sanctions to make it easier for ASN doctors who are sanctioned by violations of the Code of Ethics
Audit of BPK RI Performance on the Cooperation Scheme Agreement between the Government and Business Entities (KPBU)
Authors: Riyanda Irdham
Published: December 2020

The scheme of the Government Partnership Agreement with Business Entities (KPBUS) or known as the Public Private Partnership (PPP). It is a model agreement between the government as the owner of the land and the business entity as the business manager to carry out the socio-economic functions of the government with the size of the rights and obligations attached to each party. The implementation of the PPP agreement cannot be separated from the various legal aspects that underlie it, namely the legal aspects of the agreement, the legal aspects of state land use and the legal aspects of state finance. The existence of this legal aspect of state finance is inherent in the function and authority of BPK RI to conduct an examination of it. The type of inspection that is most appropriate for assessing the series of PPP agreement management processes, from planning to monitoring and evaluation is the type of performance inspection. Furthermore, in conducting a preliminary examination the performance of the examiner is required to be able to identify the problem before carrying out a detailed examination. There are several basic problems described in this paper, starting from the planning process to monitoring and evaluation that need to be followed up by preparing concrete audit steps and a recommendation that can be applied by the institution.
Claim for Damages in Criminal Actions to Achieve Justice for Victims
Authors: Pramana Gatra Yudha
Published: December 2020

Settlement of criminal cases, the criminal justice system pays more attention to the rights of the accused by law, while the victim's right to obtain justice in the form of compensation has not been maximally realized. This paper aims to see the implementation of the claim for compensation in criminal offenses. This study uses normative and empirical juridical methods. The results showed that the position of the victim in the Criminal Justice System, both according to the Criminal Code (KUHP) and the Criminal Procedure Code (KUHAP) are currently not equivalent to the perpetrators of criminal acts. So to file a claim for compensation, the victim of a criminal offense has not received legal certainty. Even though the Criminal Procedure Code and the Criminal Code have given a little room for victims to get true justice as a result of acts or criminal acts committed by criminals.
Effectiveness of pretrial decisions on the implementation of confiscation and its legal implications
Authors: Gunawan Ricky Indra
Published: December 2020

Pretrial is a control over the actions of investigators and public prosecutors in carrying out their duties and authority in the criminal justice process whether it has been done properly or not. The method used in this paper is a method with a juridical approach to Empirical and Normative Juridical.  The effectiveness of pretrial efforts towards the implementation of the confiscation process according to the researchers 'level of effectiveness is still questionable because as far as researchers' observations are concerned with the influence of the Constitutional Court's ruling, no community has yet filed a pretrial suit related to searches and seizures carried out by law enforcers. / PUU-XII / 2014 more people filed lawsuits for judicial petition related to the determination of suspects, this is evidenced by the number of pretrial claims against the determination of suspects and the implications in pretrial decisions regarding the implementation of foreclosures with the ruling Number 21/PUU-XII / 2014  , where the confiscation action is the tip of the investigator's action in order to prove the trial, so with the decision Number 21/PUU-XII/ 2014, the implications of the investigator are required to be more careful and  lam foreclosure. The implication is also in this case that the judge in deciding and considering a pretrial object in the form of confiscation in a case will also certainly have different views because the judge can interpret the law as long as the ruling of the Constitutional Court Number 21 / PUU-XII / 2014 which stipulates the seizure as a pretrial object has not been determined explicitly in the legislation.
Legal Protection of Children as Commercial Sex Workers in Human Trafficking Crime
Authors: Syapriyani Intan
Published: December 2020

Child protection is any effort made to create conditions so that every child can carry out their rights and obligations for the development and growth of children naturally, physically, mentally and socially. Child protection activities bring legal consequences, both in relation to written law and unwritten law. But in Indonesia the enforcement of human rights does not seem to pay much attention to aspects of child protection. The high crime rate of child trafficking shows that the government's efforts to protect child protection are not yet serious. The research method used is a normative juridical approach. The data used in this paper is data obtained from library materials. The results of this study note that the form of protection provided by Law No. 35 of 2014 concerning Child Protection is stipulated in Article 68 which states that special protection for child victims of abduction, sale and / or trafficking is carried out through surveillance, protection, prevention efforts, care and rehabilitation. While the protection of children as victims of trafficking in persons, based on the law. Number 21 of 2007 concerning Eradication of Trafficking in Persons Crimes regulates the protection of witnesses and victims, criminal acts carried out under the Law. Number 13 of 2006 concerning Protection of Witnesses and Victims. The protection model based on Law Number 21 Year 2007 regarding PTPPO does not differentiate between children and adults. Victim witnesses and reporters in child cases must receive protection and legal assistance. The implementation of the Child Protection Act (UUPA) in Indonesia is still very difficult to be taken seriously and is still an obstacle. The reason is none other than the number of people who have become consumers or users of child sex worker services.
Police Discretion in Traffic Criminal Cases Committed by Children
Authors: Agustina Sylvia Claudia , Siswanto Heni , Rosidah Nikmah
Published: December 2020

Traffic crimes committed by children generally occur because of negligence. The problem of this research is how the implementation of police discretion in traffic criminal cases committed by children and why there are obstacles in the implementation of police discretion in traffic criminal cases carried out by children. The problem approach in this study uses a normative juridical approach. Data collection is done by library research. Data were analyzed qualitatively to obtain research conclusions. The results showed that the implementation of police discretion in traffic criminal cases by children is a form of settlement of cases outside the court carried out with a peace process based on good faith between the parties involved in traffic accidents to pursue settlement in a family way. The settlement of a traffic accident case does not have to be a criminal punishment or the imposition of a criminal sanction, in this case based on the occurrence of an act, if it occurs due to negligence and error not on the suspect. Factors that impede the implementation of police discretion in traffic criminal cases committed by children are the limited number of members of the Metro Police Traffic Satlantas in handling traffic cases, incomplete data and information submitted by the perpetrators and victims involved in traffic criminal cases, so that the perpetrators and victims only provide data deemed not potentially detrimental to their party. Cultural Factors, namely the personal character of the offender, victim and his family who do not support the settlement of cases outside the court.
El impacto de experiencias de práctica pedagógica y educativa en la formación inicial de docentes de un programa de licenciatura en inglés
Authors: Fernández David Fernando
Published: December 2020

La educación erigida a partir del conocimiento es fundamental para el desarrollo y progreso de las sociedades modernas; de ahí la necesidad de comprender el alcance que tienen las prácticas pedagógicas en la formación inicial de futuros maestros (Lopes & Blázquez, 2012; MEN, 2013). Por un lado presentamos un estudio mixto que incluye análisis de corte cualitativo y cuantitativo para medir y caracterizar el impacto en el entorno educativo de las prácticas pedagógicas de la Licenciatura en Inglés de una Universidad estatal en Colombia. En segundo lugar, se analizan las opiniones y percepciones de rectores, coordinadores académicos, profesores cooperadores, practicantes y asesores de práctica involucrados en el proceso de práctica del programa a través de cinco instrumentos tipo encuesta con escala de Likert (Campoy & Gómez, 2009). Finalmente, se presentan los resultados y las recomendaciones a la comunidad académica interesada en promover una reestructuración de los procesos de prácticas pedagógicas en los programas de lenguas extranjeras. Reformas en línea con políticas públicas de formación pedagógica inicial, expectativas y necesidades de formación docente con miras a superar el insularismo asignaturista en los planes de estudio actuales.
Prácticas de los estudiantes en el espacio de la cafetería de un colegio público
Authors: Monsalve Flórez Jhon Alexánder
Published: December 2020

Este artículo de reflexión surge de una investigación cualitativa, orientada desde el modelo hermenéutico-interpretativo, que utiliza la técnica de observación directa de las Ciencias Sociales. La pesquisa se enmarca dentro de la línea “Prácticas pedagógicas” del Grupo de Investigación Cultura y Narración en Colombia (Cuynaco), adscrito a la Escuela de Idiomas de la Universidad Industrial de Santander; así mismo, recibe el apoyo metodológico de la Maestría en Métodos y Técnicas de Investigación Social, de la Escuela de Historia de la misma universidad. El objetivo de la pesquisa es analizar las prácticas de los estudiantes cuando utilizan el espacio de la cafetería en un colegio público de Girón, Santander. Para ello, se propone, luego de la observación, el proceso de categorización de la información recolectada, mediante el análisis de contenido. Los hallazgos se describen en función de cuatro categorías: a) Comportamientos habituales de los sujetos en las filas para compra de productos, b) Comportamientos habituales de los sujetos que no compran en cafetería, pero utilizan el espacio, c) Relaciones de poder y d) Inestabilidad de la concurrencia estudiantil en la cafetería. Se concluye, entre otras cosas, que la práctica más común de los estudiantes en el espacio de la cafetería es el juego, aunque, por su naturaleza, este sea valorado negativamente por los docentes y directivos de la institución.
Proximate composition and GC-MS analysis of ethanol extract of Solanum spirale Roxb.
Authors: Payum Temin
Published: December 2020

Solanum spirale Roxb. is abundantly grown in eastern Himalayan regions. The shoot is used as a vegetable as well as medicine to control high blood pressure. The present study was carried out to profile the phytochemical compositions, mineral contents and proximate composition of the Solanum spirale shoot. GC-MS was used for the identification of phytochemicals and methods described in standard protocols were used to study minerals and proximate composition. A total of 40 phytochemicals were recorded from the ethanol extract. Mineral contents of the sample 0.115 (Fe), 0.07 (Mn), 0.015 (Cu), 0.040 (Zn), 2.25 (Mg), 3.08 (Na) and 16.7 (K) mg/g  while proximate composition were  76.25± 0.093 % (moisture)3.82±0.26 % (Carbohydrate), 12.54±0.08% (Total ash), 0.39±0.98% (Crude protein), 6.12±1.07 % (Crude fibre), 0.37±0.07 % (Crude fat). (Z,Z)-6,9-Cis-3,4-epoxy-nonadecadiene occupied highest area percentage in TIC peak report with 24.55%, followed by Pentadecanoic acid with 18.81 percent, with Pentadecane with 9.99%, Hexadecanoicacid, Ethyl ester with 8.64%, (2E)(7R,11R)-3,7,11,15-Tetramethylhexadec-2-en-1-ol with 7.75%. Useful phytocompounds related to health problems including anticancer, anti-inflammatory, antioxidant, antitumor, cardioprotective, hypocholesterolemic, increase zinc bioavailability, inhibit uric acid formation, antibacterial, anti-inflamatory, antioxidant etc. are major components and such findings advocate Solanum spirale as a nutraceutical herb.
Molecular markers of genes Pl6, Pl13 and Plarg for sunflower breedomg on resistance to downy mildew
Authors:   V.S. Pustovoit All-Russian Research Institute of Oil Crops (VNIIMK), Ramazanova S.A. , Badyanov E.V. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops (VNIIMK), Guchetl S.Z. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops (VNIIMK)
Published: December 2020

One of the most dangerous diseases on sunflower is downy mildew caused by oomycete Plasmopara halstedii. Introduction of dominant genes of resistance to this pathogen into a host-plant is the most effective economic and ecologically safe method of this pathogen control. The current DNA-technologies allow controlling these genes presence at the any stage of breeding. Currently, the genes Pl6, Pl13 and Plarg are the most effective ones controlling resistance to the most races of P. halstedii. We approbated known from the literary sources two STS and two SSR-markers of these genes on the lines and breeding samples. Three studied molecular markers – HаP3 (locus Pl6), ORS1008 (locus Pl13) and ORS509 (locus Plarg) – allowed us identifying the mentions genes in lines and breeding samples of VNIIMK. The studied DNA-markers can be interested in marker-associated sunflower breeding on resistance to a downy mildew pathogen.
Impact of temperature and air moisture on pollen viability
Authors:   V.S. Pustovoit All-Russian Research Institute of Oil Crops (VNIIMK), Starikova D.V. , Syrova Yu.D. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops (VNIIMK), Gorlova L.A. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops (VNIIMK)
Published: December 2020

The environments have a direct impact on formation and functioning of the generative organs in plants. Parameters characterizing viability of pollen grains are closely linked with weather conditions, especially temperature and air moisture. Very often a phase of a beginning of flowering of winter rapeseed (end of March – beginning of April) lasts in unfavourable conditions. In April 2020, we studied influence of the main weather factors (frosts, low moisture) on germination of pollen grains of the varieties Loris, Sarmat and hybrids 40059 × Jesper 16– 132 and 40008 × INRA of winter rapeseed bred in VNIIMK. Pollen viability was determined by B.A. Trankovsky’s method, accounting amount of germinating pollen grains on the artificial nutrient medium, calculating a percentage of germinating pollen grains to their total quantity. We determined optimal concentration of sucrose solution (20%) in a nutrient medium for germination of pollen of winter rapeseed varieties and hybrids. Due to our results, lowered air temperatures (from -0.5 to -1.9 оС) combined with air moisture from 39 to 86% in a period of beginning of crop flowering negatively influenced on germination of pollen grains. Viability of pollen of the varieties Loris and Sarmat was in average 47 and 37%, respectively. Pollen grains of the hybrids (F1 40059 × 52 Jesper 16-132 and F1 40008 × INRA) had less viability – 38 and 21%, respectively, this certifies higher susceptibility of tissues of the reproductive organs to low temperature and moisture.
Örgüt yararına ahlaki olmayan davranışın belirleyicileri: duygusal bulaşıcılığın düzenleyicilik rolü
Authors: GÜRSOY Ali , KÖKSAL Kemal , TOPCU Mustafa Kemal
Published: December 2020

Örgüt yararına ahlaki olmayan davranışlar, sosyal ve etik kuralları yok sayan fakat örgüt için fayda yarattığı düşünülen davranışlar olarak ifade edilebilir. Bu davranışlar kısa dönemde örgüt yararına gibi görünse de uzun dönemde örgüte zarar verebilmektedir. Araştırma, çalışanların örgüt yararına ahlaki olmayan davranışlarının belirleyicilerini tespit etmek amacıyla yöneticiye duyulan güven ve örgütsel bağlılığın bu davranışlar üzerindeki etkisini belirlemek ve duygusal bulaşıcılığın bu ilişkideki rolünü ortaya çıkarmak amacıyla yapılmıştır. Bunun için bir kamu kuruluşundaki 198 çalışandan veri toplanmıştır. Kamu kurumu eğitim alanında hizmet veren bir kurumdur. Veriler kolayda örnekleme yöntemiyle toplanmıştır. Ölçeklerin geçerlilikleri ve güvenilirlikleri kontrol edildikten sonra, değişkenler arasındaki ilişki korelasyon ve regresyon temelli yol analiziyle incelenmiştir. Yöneticiye duyulan güven ve örgütsel bağlılığın örgüt yararına ahlaki olmayan davranışları olumlu ve anlamlı bir şekilde etkilediği, örgütsel bağlılığın yöneticiye duyulan güvenle örgüt yararına ahlaki olmayan davranış arasındaki ilişkide kısmi aracılık rolüne sahip olduğu; ayrıca, yöneticiye duyulan güven ve örgütsel bağlılığın örgüt yararına ahlaki olmayan davranış üzerindeki etkisinde duygusal bulaşıcılığın düzenleyicilik etkisinin olduğu tespit edilmiştir. Duygusal bulaşıcılık, yöneticiye güven ve örgütsel bağlılığın örgüt yararına ahlaki olmayan davranış üzerindeki pozitif ve anlamlı etkisini güçlendirmektedir.
PASSer: Prediction of Allosteric Sites Server
Authors: Tian Hao , Jiang Xi , Tao Peng
Published: December 2020

Allostery is considered important in regulating protein's activity. Drug development depends on the understanding of allosteric mechanisms, especially the identification of allosteric sites, which is prerequisite in drug discovery and design. Many computational methods have been developed for allosteric site prediction using pocket features and dynamics information. Here, we provide a novel ensembled model, consisting of eXtreme gradient boosting (XGBoost) and graph convolutional neural network (GCNN) to predict allosteric sites. Our model can learn both physical properties and topology structure without any prior information and exhibited good performance under several indicators. Prediction results have shown that 84.9% of allosteric pockets in the testing proteins appeared in the top 3 positions. The PASSer: Protein Allosteric Sites Server (https://passer.smu.edu), along with a command line interface (CLI, https://github.com/smutaogroup/passerCLI) provide insights for further analysis in drug discovery.
Powerful Statistical Tests for Ordered Data
Authors: Koefinger Juergen , Hummer Gerhard
Published: December 2020

The inference of models from one-dimensional ordered data subject to noise is a fundamental and ubiquitous task in the physical and life sciences. A prototypical example is the analysis of small- and wide-angle solution scattering experiments using x-rays (SAXS/WAXS) or neutrons (SANS). In such cases, it is common practice to check the quality of a fit by using Pearson's chi-square test, which ignores the order of the data. We usually plot the residuals and check visually for systematic deviations without quantifying them. To quantify these deviations, we developed test statistics based on the distributions of the lengths of the runs of the signs of the residuals. Specifically, we use the probability of run-length distributions, for which we provide analytical expressions, to rank them and to calculate their P-values. We introduce the Shannon information distribution as an elegant and versatile tool for calculating P-values. We find that these distributions follow shifted gamma distributions, such that they are summarized by three parameters only. We show for a set of six models that our test statistics are more powerful than Pearson's chi-square test and common sign-based tests. We provide an open source Python 3 implementation of our tests free of charge at https://github.com/bio-phys/hplusminus.
A Floating Mould Technique for the Programmed Assembly of Protocells into Protocellular Materials Capable of Non-Equilibrium Biochemical Sensing
Authors: Galanti Agostino , Tortolero Rafael Moreno , Azad Raihan , Cross Stephen , Davis Sean , Gobbo Pierangelo
Published: December 2020

Despite important breakthroughs in bottom-up synthetic biology have recently been achieved, a major challenge still remains the construction of free-standing, macroscopic and robust materials from protocell building blocks that are stable in water and capable of emergent behaviours. Herein we report a new floating mould technique for the fabrication of millimetre- to centimetre-sized protocellular materials (PCMs) of any shape that overcomes most of the current challenges in prototissue engineering. Significantly, this technique also allowed us to generate 2D periodic arrays of PCMs that displayed an emergent non-equilibrium spatiotemporal sensing behaviour. These arrays were capable of collectively translating the information provided by the external environment and encoded in the form of propagating reaction-diffusion fronts into a readable dynamic signal output. Overall, our methodology opens up a route to the fabrication of macroscopicand robust tissue-like materials with emergent behaviours, providing a new paradigm of bottom-up synthetic biology and biomimetic materials science.
Beyond Generative Models: Superfast Traversal, Optimization, Novelty, Exploration and Discovery (STONED) Algorithm for Molecules using SELFIES
Authors: Nigam AkshatKumar , Pollice Robert , Krenn Mario , dos Passos Gomes Gabriel , Aspuru-Guzik Alan
Published: December 2020

Inverse design allows the design of molecules with desirable properties using property optimization. Deep generative models have recently been applied to tackle inverse design, as they possess the ability to optimize molecular properties directly through structure modification using gradients. While the ability to carry out direct property optimizations is promising, the use of generative deep learning models to solve practical problems requires large amounts of data and is very time-consuming. In this work, we propose STONED – a simple and efficient algorithm to perform interpolation and exploration in the chemical space, comparable to deep generative models. STONED bypasses the need for large amounts of data and training times by using string modifications in the SELFIES molecular representation. We achieve comparable performance on typical benchmarks without any training. We demonstrate applications in high-throughput virtual screening for the design of drugs, photovoltaics, and the construction of chemical paths, allowing for both property and structure-based interpolation in the chemical space. We anticipate our results to be a stepping stone for developing more sophisticated inverse design models and benchmarking tools, ultimately helping generative models achieve wide adoption.
GENDER AS THE OBJECT OF EVALUATION IN MEDIA DISCOURSE (on English and Russian mass media)
Authors: Цветкова Ольга Дмитриевна
Published: December 2020

В статье рассматриваются различные формы оценки в дискурсе СМИ гендерных характеристик участников общественно-политических процессов в англоязычных странах и России. Определена ретроспективная динамика содержания данной оценки, а также формы - скрытые и открытые - ее выражения.

The article debates various forms of evaluation of gender in media in Anglo-Saxon and Russian press. The retrospective dynamics of its content, as well as the forms of this evaluation, are disclosed.
Taxonomic updates to Artocarpus subgenus Pseudojaca (Moraceae), with a particular focus on the taxa in Singapore
Authors: Gardner E.M. , Zerega N.J.C.
Published: December 2020

The breadfruit genus (Artocarpus J.R.Forst. & G.Forst., Moraceae) has 16 species in Singapore, 14 of them native. The following taxonomic changes in Artocarpus subgenus Pseudojaca Trécul, based on recent phylogenetic work, are presented with diagnostic characters. Artocarpus griffithii (King) Merr. is reinstated as distinct from A. lamellosus Blanco (which is called A. nitidus Trécul in the earlier literature), also requiring the reinstatement of the following taxa not found in Singapore: A. borneensis (Merr.) F.M.Jarrett, A. humilis Becc., A. vrieseanus Miq. var. subsessilis F.M.Jarrett and A. xanthocarpus Merr. Artocarpus dadah Miq. is reinstated as distinct from A. lacucha Roxb. ex Buch.-Ham., thereby necessitating the reinstatement of the following taxa not found in Singapore: A. fretessii Teijsm. & Binn. ex Hassk., A. ovatus Blanco, and A. vrieseanus var. refractus (Becc.) F.M.Jarrett. Artocarpus gomezianus Wall. ex Trécul is restricted to the type subspecies, and A. zeylanicus (F.M.Jarrett) E.M.Gardner & Zerega, formerly a subspecies, is elevated to species level. Thirteen lectotypes and two neotypes are designated.
MODELO PARA ESTUDIAR LA ANEMIA EN RESTOS OSEOS PREHISPANICOS CON INDICENCIA EN MATERIAL CULTURAL
Authors: Espino David Gonzáles
Published: December 2020

Las enfermedades prehispánicas han sido estudiadas bajo diversos formatos que han recurrido a; metodologías, máquinas y otros recursos. Nuestro objetivo es determinar un modelo que permita garantizar el estudio de una enfermedad prehispánica como la anemia, por cuanto se proponen las dimensiones: paleopatología, restos óseos, materiales culturales y análisis de laboratorio. Debemos incidir en buscar una relación entre las enfermedades y los materiales culturales. Restos líticos, minerales, cerámica y tierras encaminan propuestas complementarias para combatir la anemia, se determinan como indicadores la criba orbitalia e hiperostosis porotica que son materia de estudio de disciplinas como la Paleopatología y Bioarqueología, finalmente debemos destacar que, en el Perú, la anemia es un grave problema de salud que afecta al 35.6% de los niños entre 6 y 59 meses de edad.
NECESIDAD DE PLAN DE INTERVENCIÓN PARA MEJORAR LA PREVENCIÓN EN SALUD BUCAL EN ESCUELAS PÚBLICAS EN PERÚ
Authors: Portocarrero Mondragón Katia Roxana , Portocarrero Mondragón Juan Pablo , La Serna Solari Paola Beatriz
Published: December 2020

El objetivo fue relacionar el nivel de conocimientos y actitudes en salud bucal en los maestros. Para lo cual dirigimos una encuesta virtual a maestros de reconocidas instituciones educativas públicas en Perú para determinar los niveles de conocimiento y los hábitos en prevención de salud bucal. Estudio descriptivo, observacional de corte transversal. Utilizamos la escala de Likert para determinar los niveles de conocimientos y actitudes en los maestros. Prueba estadística utilizada para relacionar las variables fue Coeficiente de Pearson. Tuvo como resultados que 586 maestros peruanos de Instituciones educativas públicas, quienes completaron el cuestionario virtual. De los cuales, 311 (53.07%) fueron mujeres, 325(55 %) con edades de 41 a 61 años. El nivel de conocimiento y las actitudes de prevención en salud bucal fueron 47. 06% (inadecuado) y 26.47% (adecuado), respectivamente. El coeficiente de correlación de Pearson utilizado arrojó 0.5 Se tiene como conclusión los maestros peruanos de instituciones educativos públicas presentaron inadecuados conocimientos y actitudes en cultura de prevención en salud bucal, lo que nos muestra la necesidad de elaborar un plan de intervención para mejorar dicho panorama. Se presentó relación directa entre las variables estudiadas, según el coeficiente de Pearson.
GASTO DE BOLSILLO EN SALUD Y RIESGO DE POBREZA EN HOGARES PERUANOS. PERÚ 2017
Authors: Guerrero-Ojeda Guillermo Arturo
Published: December 2020

El objetivo fue determinar la relación entre gasto de bolsillo en salud y riesgo de pobreza mediante una regresión logística multinomial en el año 2017 Fue un estudio  descriptivo, no experimental transversal, la muestra de estudio son los hogares con gasto de bolsillo de las viviendas seleccionadas de la Encuesta Nacional de Hogares, la variable dependiente fue Pobreza con tres categorías: pobre extremo, pobre no extremo y no pobre, se utilizó la metodología de Xu K en el estudio de las variables en salud. Como resultados se obtuvo que el aseguramiento fue: 44,2% al SIS, 28,3% a EsSALUD, 24,2% no asegurados y 3,3% a otro tipo de seguro, el gasto de bolsillo en salud fue de 63,0%. Las variables que relacionan salud y pobreza en forma directa son: gasto catastrófico, gasto de bolsillo y número de asegurados del hogar. El gasto en medicinas es del 39,2%. El índice Gini para este gasto es 0,690 Se concluye que según lo contemplado en la ley Nº 29344, aún no se cumple por el no aseguramiento. El gasto de bolsillo es alto aproximadamente el triple de lo recomendado por la OMS, es desigual y concentrado en los quintiles de gasto 4 y 5, que son los de mayor capacidad de pago y es la principal fuente de financiamiento de la salud de los hogares. EsSALUD y el SIS contribuyen con la tercera parte de los cuidados de salud. Los hogares destinan mayor gasto en medicinas, servicio dental y consultas médicas originando gastos catastróficos (40% en gasto de bolsillo del gasto familiar), aumentando la probabilidad de empobrecimiento.
RELACIÓN ENTRE LA PERIODONTITIS Y ARTRITIS EN UN PACIENTE CON DIABETES MELLITUS. PARTE I. REPORTE DE CASO Y REVISIÓN DE LITERATURA
Authors: Ojeda Gómez Roberto Carlos , López Monja Martha Aurora , Soto Ramirez Carmen Elena Sarahi
Published: December 2020

La enfermedad periodontal es un proceso inflamatorio crónico activado por bacterias periodonto patógenas con una alta carga microbiana. Ésta inicia por una serie de microorganismos complejos, así como la susceptibilidad del individuo; con varios factores sistémicos, siendo la diabetes mellitus, la más común.
En esta revisión se resume la evolución de la teoría de la infección focal para el conocimiento actual de la fisiopatología de la enfermedad periodontal y se presenta una actualización de los mecanismos y las relaciones entre la periodontitis crónica y enfermedades sistémicas que incluyen artritis reumatoide y diabetes mellitus.
Para la revisiónn de la literatura, se diseñó un estudio descriptivo basado en la búsqueda sistemática de literatura en la base de datos: PUBMED y se reporta un caso atendido en una clínica universitaria, donde describe a una paciente femenino de 60 años de edad, que acudió al centro de prácticas pre clínica y clínica de Estomatología de una universidad privada del norte del país, la cual la paciente presenta diabetes mellitus tipo I con 10 años de evolución, la paciente también refiere gastritis con el mismo tiempo de evolución que la diabetes, y artritis con un tiempo de evoluciónn de 4 años y sin ningún tipo de medicación. Al examen clínico la paciente presenta una prótesis total removible superior en mal estado, presenta edentulismo parcial en el maxilar inferior, caries dental en las piezas dentarlas 31, 32, 34, 35, 41, 42, 43, 45, 47 y a la vez presenta lesiones no cariosas.
NILAI PENDIDIKAN KARAKTER DALAM CERITA ANAK "DOA UNTUK AMANG KANI" KARYA SITI MAKIAH
Authors: Jahdiah Jahdiah
Published: December 2020

Cerita anak  termasuk dalam sastra anak yang disajikan khusus untuk anak-anak. Tulisan ini bertujuan mendeskripsikan tentang nilai-nilai pendidikan karakter dalam cerita anak Doa untuk Amang. Masalah yang diangkat dalam penelitian ini adalah nilai-nilai pendidikan karakter apa saja yang ada dalam cerita anak Doa untuk Amang  Kani dan indikator apa saja yang ada dalam setiap nilai pendidikan karakter tersebut. Penelitian ini termasuk penelitian kuantitatif dengan menggunakan metode deskriptif. Teknik yang digunakan dalam penelitian ini adalah teknik catat. Hasil analisis data bahwa dalam cerita anak Doa untuk Amang Kani terdapat lima nilai pendidikan karakter, yaitu (1) Keimanan dan ketakwaan, (2) Kejujuran. (3) Kecerdasan (4) Ketangguhan. (5) Kepedulian. Kelima nilai pendidikan karakter tersebut masing-masing mempunyai indikator.
CODE-MIXING OF JAVANESE LANGUAGE AND BAHASA INDONESIA IN THE FRIDAY PRAYER SERMON AT MIFTAHUL HIDAYAH MOSQUE, PENDEM VILLAGE, CITY OF BATU, EAST JAVA
Authors: Muslimin Afif Ikhwanul
Published: December 2020

Code-mixing phenomenon which appears in different settings and contexts creates interest for investigation. This research is aimed to analyze the elements of code mixing in Friday prayer sermon, the reasons underlying speaker to mix code, and the responses of audience. This is a qualitative research by implementing content analysis. Based on the analysis, the elements of code mixing in the sermon were in the form of words, phrases, and clauses. The reasons causing speaker mixing the code are making the sermon easy listening, making his sermon accepted, understanding listener that old man preferred local language in sermon, matching sermon with social condition, making himself accepted, making ease to deliver the sermon, making sermon more communicative, and making the sermon get in touch with the listeners. Then, based on the questionnaires which were given to 25 respondents, there were 22 people understood the sermones. However, 10 people of them said that the sermones should be delivered in Bahasa Indonesia only. They thought that the sermon would be more easy listening, more understandable, and created more comfortable listening. On the other hand, they thought many listeners were the outsiders of the village. Hence, it is concluded that phenomenon appears to consider context, goal, and audience.
Environmental Disclosures and Environmental Management Strategies – A study of Pakistani Listed companies
Authors: Waris Ali  , Muhammad Abdul Basit Memon  , Muhammad Mudassar Anwar  , Rehana Kouser
Published: December 2020

The main purpose of this paper is to understand the environmental disclosure by listed companies of Pakistan in the light of legitimacy theory. Furthermore, it highlights the environmental management strategies pursued by them. This research used a content analysis research method to codify the reported information in the annual reports into the environment related themes. The data analysis results revealed that the sampled companies appear to give little importance to environmental issues. The companies which have disclosed mainly reported about ‘environmental pollution’, ‘energy’, and ‘conservation of natural resources’ themes; and provided declarative types of disclosure about them. As for as environmental strategies are concerned only a few non-financial companies have followed proactive environmental strategies and made real efforts to address environmental issues. These results seem to reflect that the companies have disclosed environment related information in the annual reports in order to legitimize their existence.
Impact of adjuvant intrabladder therapy on quality of life in patients, suffering musculo-noninvasive cancer of the bladder
Authors: Коstyev F. І. , Bondar О. V. , Chystiakov R. S. , Lysenko V. V.
Published: December 2020

Objective. Comparative estimation of quality of life in patients with a high-risk musculo-noninvasive cancer of the bladder was accomplished while conduction of adjuvant intrabladder hyperthermic chemotherapy and immunotherapy with BCG vaccine.
Маterials and methods. Depending on kind of treatment, the patients were distributed into two groups: Group I - 44 patients, to whom adjuvant intrabladder immunotherapy with BCG vaccine was applied, and Group II - 41 patients, to whom intrabladder chemotherapy was conducted, using the system for local hyperthermy Combat BRS.
Results. The data from the patients interviewed, using EORTC QLQ-30 questionnaires, confirmed better quality of life in patients of Group II, who obtained intrabladder hyperthermic chemotherapy, peculiarly in accordance to indices of physical status, social adaptation and intoxication. In accordance to data of the patients’ interviewed with the help of FACT-BL questionnaire, also better results were obtained in patients of Group II in accordance to the social and functional well-being status, the urination quality and values of indices of the «Cancer of the Bladder» scale.
Conclusion. Higher quality of life was noted in patients of Group II, who obtained intrabladder hyperthermic chemotherapy. The lower quality of life in patients of Group I, who obtained immunotherapy with BCG vaccine, was connected with multiple side effects and enhanced toxicity of this therapy, accordingly.
АSSOCIATION OF COLOPROCTOLOGISTS OF UKRAINE. NATIONAL RECOMMENDATIONS OF ASSOCIATION OF COLOPROCTOLOGISTS OF UKRAINE FOR MANAGEMENT OF PATIENTS WITH HEMORRHOIDS, аdаpted for Guidelines of European Society of Coloproctologists (ЕSСP)
Authors: Zakharash М. P. , Usenko О. Yu. , Poyda О. І. , Boyko V. V. , Таmm Т. І. , Мylytsya М. М. , Gaponov V. V. , Zakharash Yu. М. , Bakhar G. А. , Lozynska L. Yu. , Paliyenko R. К. , Balytskyi V. V. , Sargosh І. D. , Аndriyets V. S.
Published: December 2020

АSSOCIATION OF COLOPROCTOLOGISTS OF UKRAINE. NATIONAL RECOMMENDATIONS OF ASSOCIATION OF COLOPROCTOLOGISTS OF UKRAINE FOR MANAGEMENT OF PATIENTS WITH HEMORRHOIDS, аdаpted for Guidelines of European Society of Coloproctologists (ЕSСP)
Long Progression-free-survival Pancreatic Carcinosarcoma Under Gemcitabine-nabpaclitaxel First Line Chemotherapy
Authors:   Medical Oncology Service, Virgen de la Salud Hospital, Toledo, Spain
Published: December 2020

Carcinosarcoma of the pancreas is a rare entity with short case series reported in the literature. Diagnosis is established by immunohistochemical examination including both carcinomatous and sarcomatous components. Prognosis is usually limited to 6-9 months life expectancy. Standard chemotherapy regimen is not well defined. We present a case of pancreatic carcinosarcoma with long-time progression-free-survival under first line chemotherapy treatment with gemcitabine-nabpaclitaxel combination. Tumor histopathological and clinical characteristics are reviewed.
Roma Health Mediators: A Neocolonial Tool for the Reinforcement of Epistemic Violence?
Authors: Petraki Ioanna
Published: December 2020

Scientific articles in medical journals regarding Roma have produced a type of problematic consensus narrative that is reinforced through its formulaic repetition. Roma health mediator (RHM) programs seem to have evolved from and currently be part of this consensus narrative. In this article I examine the potential use of RHMs, even if unintended, as a neocolonial tool for the reinforcement of epistemic violence against Roma, using a critical analysis of four empirical stories from the field. I explore the above hypothesis through critical reflexive anthropology, and postcolonial and intersectional studies, as well as by using elements of the self-ethnographic approach. I argue that the epistemic violence can be seen as resulting from the interplay between the Subject (i.e., health professional or researcher), the Object (i.e., Roma as “Other”), and the practices that result (i.e., discourse or consensus narrative production through the interpretation of the scientific data). I conclude with tools that could help reduce the epistemic violence against Roma within the health sector, suchas cross-disciplinary collaboration, participatory action research (PAR), (self-)reflection, critical theory, and the dialogic creation of scientific knowledge.