bluuebunny/crossref_metadata_2025 huggingface dataset:
A formação continuada de professores de Educação Física a partir de um espaço coletivo escolar: uma experiência no Brasil
Authors: Vedovatto Dijnane , Rubino Marília
Published: May 2021

A prática docente exige diversos saberes, que não se esgotam na formação inicial, isso foi percebido por meio da experiência de uma das autoras ao iniciar a carreira docente, levantando muitos questionamentos, que desencadearam em uma pesquisa de mestrado profissional em educação sobre a temática. Assim, a formação continuada é de grande importância para a prática profissional, tendo como desafio abordagens baseadas na realidade dos professores. Este artigo teve como objetivo identificar e analisar os processos formativos no local de trabalho realizado dentro do Horário de Trabalho Pedagógico Coletivo – HTPC, da área específica de Educação Física, ofertado pela Secretaria Municipal de Educação do interior do estado de São Paulo, bem como investigar as percepções de 30 professores e uma coordenadora sobre possíveis influências destes processos formativos no exercício da docência. Tal pesquisa é de natureza qualitativa, possui características de estudo de caso, tendo como instrumentos da coleta de dados a análise documental, questionários e entrevista semi estruturada. Apresenta como orientação teórica a literatura que fundamenta a discussão sobre a aprendizagem e desenvolvimento profissional da docência, na perspectiva da profissionalização do ensino. Os resultados indicam que as ações desenvolvidas no HTPC promovem diversos saberes que contribuem para os múltiplos desafios da prática pedagógica, uma vez que a proposta do HTPC prevê estreita relação com a prática dos professores, bem como um protagonismo, o que gera um movimento de constante reflexão entre a prática desenvolvida nas escolas, e a formação continuada no HTPC. A criação e manutenção do HTPC em questão permitiu significativo desenvolvimento profissional, o que contribuiu para o trabalho docente nas escolas, e para o processo de profissionalização do ensino.
Preparación deportiva en el Goalball: una revisión sistemática
Authors: Fernández Muñoz Mónica Paulina , Campos Campos Kevin , Luarte Rocha Cristian , Castelli Luis Felipe
Published: May 2021

El objetivo del estudio fue describir el conocimiento científico producido en los últimos 10 años, respecto a la preparación deportiva (PD) con énfasis en el sistema de entrenamiento en atletas de Goalball de diferentes niveles competitivos. Para eso, fue realizada una revisión sistemática en las principales bases de datos: Web Of Science, Scopus, PubMed, SciELO y LILACS entre enero de 2010 hasta enero de 2021. Se identificó un total de 136 estudios donde posterior a la eliminación de duplicados, aplicación de los criterios de exclusión e inclusión, conforme procedimientos presentados en el flujograma PRISMA, se seleccionaron 15 artículos originales para su análisis cualitativo. Los principales resultados evidenciaron que el metabolismo anaeróbico aláctico es determinante en la modalidad, existiendo una fuerte relación entre la fuerza/potencia de extremidades superiores e inferiores con el lanzamiento del balón. Por otro lado, existen patrones repetitivos en la técnica de lanzamiento según género, así como también efectividad según tipo de lanzamiento, recalcando que la velocidad del lanzamiento es necesaria para la consecución de un gol. De igual forma, existen funciones predominantes según las posiciones dentro del campo de juego que son necesarias considerar. Finalmente, el entrenamiento mental favorece la adquisición de técnicas que ayudan a superar obstáculos imprevistos durante una competición. Se observa la necesidad de mayores evidencias y conocimientos acerca de la PD en dicha modalidad ya que constituyen factores imprescindibles que deben ser contemplados por los entrenadores, en función de optimizar el rendimiento competitivo de sus atletas.
In vitro inhibitory potential of avocado fruits, Persea americana (Lauraceae) against oxidation, inflammation and key enzymes linked to skin diseases
Authors: M. Hürkul Muhammed , Sarialtin Sezen Yilmaz , Köroğlu Ayşegül , Çoban Tülay
Published: May 2021

Avocado (Persea americana Mill.) is a member of Lauraceae with one-seeded berry fruit and cultivated in all tropical, subtropical regions in the world and in the Southern coast region of Turkey. Oxidative damage caused by UV can trigger inflammation, resulting in serious inflammatory skin diseases including eczema, seborrheic dermatitis, hyperpigmentation and ageing. Enzyme inhibitors involved in melanogenesis, such as tyrosinase, have been used recently for hyperpigmentation and skin diseases in cosmetic products. Objective: This study aimed to evaluate the antioxidant, anti-inflammatory, anti-tyrosinase activities and total polyphenolic contents of the different parts of P. americana fruit. Methods: The fruit was divided into exocarp, mesocarp, seed, and then methanol and n-hexane extracts were prepared. DPPH and ABTS free radical scavenging capacities and inhibitory potentials on lipid peroxidation were determined to investigate the antioxidant potentials of the extracts. Anti-inflammatory activities of the extracts were evaluated by measuring the stabilization level of the human red blood cell membrane. The tyrosinase inhibitory activities of the samples were determined using mushroom tyrosinase. Results: In general methanol extracts possessed remarkable higher DPPH free radical scavenging activities than n-hexane extracts. The highest activity was determined in methanol extracts of seed (4.17 ± 0.04 mg/mL) followed by exocarp (5.25 ± 0.05 mg/mL). Overall methanol extracts possessed higher ABTS free radical scavenging activities than n-hexane extracts. The greatest ABTS free radical scavenging activity was obtained in methanol extracts of seed (0.03 ± 0.01 mg/mL). In the anti-lipid peroxidation assay, the greatest activity was noticed in methanol extracts of seed (7.71 ± 0.36 µg/mL) followed by exocarp (12.12 ± 0.34 µg/mL), while all n-hexane extracts were inactive. Overall methanol extracts exhibited higher anti-inflammatory and antioxidant properties than n-hexane extracts. However, the maximum anti-tyrosinase activity was determined in n-hexane extracts of exocarp (0.40 ± 0.01 mg/mL) followed by seed (0.46 ± 0.01 mg/mL). Conclusions: These extracts are promising candidates for use as natural products-based antioxidant and anti-inflammatory properties in inflammation-related disease, and also anti-tyrosinase properties in dermatological applications.
Potential distribution in Colombia of the introduced fish Pangasianodon hypophthalmus (Siluriformes: Pangasiidae) and implications for endangered local fish
Authors: Castellanos-Mejía María Camila , Herrera Pérez Juliana , Noguera-Urbano Elkin A , Parra Edison , Jiménez-Segura Luz Fernanda
Published: May 2021

Introducción: Una de las grandes amenazas a los ecosistemas acuáticos es la introducción de especies foráneas en los ambientes naturales, lo que representa una de las principales causas de pérdida de biodiversidad en el mundo. P. hypophthalmus es una especie introducida en Colombia que comparte características de vida y hábitat con especies nativas como A. pardalis, S. cuspicaudus y P. magdaleniatum, sin embargo, su distribución es poco conocida y los efectos que tiene sobre la fauna nativa son poco explorados. Objetivos: Evaluar el potencial invasivo de P. hypophthalmus en algunas de las cuencas de la vertiente al Mar Caribe. Métodos: Utilizando registros disponibles en bases de datos, realizamos un análisis de conservadurismo de nicho entre el rango nativo e introducido de P. hypophthalmus en el programa Ecospat. Posteriormente, el área potencial de invasión de la especie no nativa y las áreas de distribución de las tres especies nativas se modelaron utilizando el algoritmo de Maxent en el programa R. Finalmente, se realizó una sobreposición de nicho geográfico entre el área de invasión potencial de la especie no nativa y el área de distribución de las especies nativas. Resultados: El análisis espacial de nicho indica que la especie no nativa presenta conservadurismo de nicho, por lo que la proyección de MNE para estimar el área de invasión es posible. Los MNE demuestran las cuatro especies analizadas prefieren zonas bajas y poco rocosas. Finalmente, la sobreposición geográfica de los nichos ecológicos de las tres especies nativas y la especie introducida arrojan valores que superan el 80 %. Conclusiones: La especie P. hypophthalmus tiene las condiciones adecuadas en las cuencas de estudio para un establecimiento pleno, además, supone un alto riesgo para los ecosistemas acuáticos y la ictiofauna nativa siendo esto fundamental para implementar control de la especie.
First pediatric case of osteomyelitis caused by Robinsoniella peoriensis
Authors: İnal Neşe , Karagöz Alper , Turhan Egemen , Hazirolan Gülşen
Published: May 2021

Robinsoniella peoriensis is a gram-positive, spore-forming, anaerobic rod. In our study, we isolated R. peoriensis from an open fracture of the left distal tibia of a three-year-old male patient. Tissue anaerobic culture was positive for R. peoriensis. It was identified with both matrix-assisted laser desorption ionization time-of-flight mass spectrometry and confirmed via 16S rRNA gene sequencing. The patient responded to ampicillin-sulbactam and amikacin antibiotic therapy. Antimicrobial susceptibility testing should be performed to guide the choice of treatment. To the best of our knowledge, this is the first report of R. peoriensis osteomyelitis in a pediatric patient and first report from Turkey.
Strategi Dinas Penerangan Kodam III/Siliwangi dalam Meningkatkan Citra Positif
Authors: Nuswantoro Gandung , Abidin Yusuf Zaenal , Paryati Paryati
Published: May 2021

Pendam III/Siliwangi dalam menjalankan tugas adalah menyampaikan informasi secara benar dan profesional. Memberikan tanggapan yang simpatik manakala ada suatu informasi yang dianggap dapat merugikan citra positif Kodam III/Siliwangi. Selain itu sebagai institusi yang sekaligus agen informasi, bertugas mengolah informasi, mengelola informasi, baik untuk pihak internal maupun eksternal. Tujuan dari penelitian ini adalah untuk mengetahui strategi yang dilaksanakan oleh Pendam III/Siliwangi dalam meningkatkan citra positif. Metode penelitian yang digunakan adalah metode studi kualitatif. Adapun teknik pengumpulan data dalam penelitian ini dilakukan dengan wawancara, observasi dan dokumentasi. Kerangka berfikir atau landasan teori yang digunakan dalam penelitian ini, yaitu menggunakan teori strategi yaitu formulasi misi, tujuan dan objektif dasar perusahaan, program dan kebijakan untuk mencapainya dan metode yang diperlukan untuk memastikan bahwa strategi di implementasikan untuk mencapai tujuan-tujuan perusahaan. teori citra di dalamnya terdapat jenis-jenis citra (mirror image, current image, wish image, multiple image). Hasil dari penelitian ini menunjukan bahwa strategi yang dilakukan Pendam III/Siliwangi yaitu melaksanakan program-progam kegiatan dalam rangka untuk meningkatkan citra positif. Dalam meningkatkan citra memperhatikan unsur citra yaitu (mirror image, current image, wish image, multiple image) sebagai acuan meningkatkan citra positif.

Pendam III/Siliwangi in carrying out the duty is to convey information correctly and professional. Provide sympathetic responses when there is information that is considered to harm the positive image of Kodam III/Siliwangi. In addition, as an institution as well as an information agent, in charge of processing information, managing information, both for internal and external parties. The purpose of this research is to know the strategy implemented by Pendam III/Siliwangi in improving the positive image. The research method used is qualitative study method. The data collection technique in this research is done by interview, observation and documentation. The framework of thinking or the theoretical basis used in this research, which is using strategy theory is mission formulation, objective and basic objective of company, program and policy to achieve it and method needed to ensure that strategy implemented to achieve company goals. image theory in it there are types of images (mirror image, current image, wish image, multiple image). The result of this research shows that the strategy of Pendam III/Siliwangi is to carry out activities programs in order to improve the positive image. In improving the image pay attention to the image element that is (mirror image, current image, wish image, multiple image) as a reference to improve the positive image.
Manajemen Humas dalam Memelihara Citra Perusahaan
Authors: Rimayanti Rimayanti , Ruhiyat Ruhiyat , Rasib Abdul
Published: May 2021

Tulisan ini menjelaskan tentang proses manajemen humas yang dilakukan oleh humas PT.Pindad (Persero) dalam rangka memelihara citra perusahaan memalui program penerimaan kunjungan industri. Penelitian yang dilakukan menggunakan paradigma konstruktivisme, metode kualitatif dan pendekatan studi kasus yang bertujuan untuk mengetahui proses pemeliharaan citra melalui kunjungan industri secara mendalam dan menyeluruh. Konsep yang digunakan adalah konsep four steps public relations dari Cutlip, Center and Broom, dengan menggunakan teknik pengumpulan data observasi partisipatori pasif, dan wawancara mendalam. Teknis analisis yang digunakan adalah reduksi data dan penyajian data. Hasil dari penelitian ini menunjukan bahwa manajemen yang dilakukan oleh Humas PT.Pindad (Persero) dalam mengelola program kunjungan industri memiliki pengaruh terhadap pemeliharaan citra yang dilakukan oleh perusahaan dan sesuai dengan konsep four steps public relations dari Cutlip, Center and Broom yakni proses perencanaan dengan menetapkan tujuan, melakukan operasionalisasi persuratan, menyiapkan tempat, membuat schedule dan rundown acara dan melakukan briefieng. Proses implementasi dengan melakukan pemaparan materi dan plant tour. Proses evaluasi beserta pencarian data dan fakta dengan mewawancarai pengunjung dan evaluasi tahunan perusahaan.

This paper describes the public relations management process carried out by public relations of PT. Pindad (Persero) in order to maintain the company's image through the industrial visit acceptance program. The research was conducted using the constructivism paradigm, qualitative methods and case study approaches that aim to find out the image maintenance process through in-depth and comprehensive industrial visits. The concept used is the concept of four steps public relations from Cutlip, Center and Broom, using passive participatory observation data collection techniques, and in-depth interviews. The analysis technique used is data reduction and data presentation. The results of this study indicate that the management carried out by Public Relations PT.Pindad (Persero) in managing industrial visit programs has an influence on image maintenance carried out by the company and in accordance with the concept of four steps public relations from Cutlip, Center and Broom namely the planning process by setting purpose, operationalize correspondence, prepare a place, make a schedule and rundown of the event and do a briefieng. The implementation process is by presenting material and plant tour. The evaluation process along with data and fact searches by interviewing visitors and annual evaluations of the company.
Kampanye Bank Indonesia dalam melawan Hoax mengenai Rupiah Emisi 2016
Authors: Rinaldi Aldi , Astuti Dyah Rahmi , Amin Dang Eif Saiful
Published: May 2021

ABSTRAK

Kampanye PR merupakan hal yang penting dilaksanakan oleh humas dalam sebuah organisasi, karena dengan kegiatan tersebut organisasi dapat mengenalkan suatu hal dengan tujuan tertentu. Humas Bank Indonesia melakukan sebuah kegiatan kampanye PR yang unik dan menarik dalam upaya mengenalkan uang Rupiah tahun emisi 2016, peneliti tertarik melakukan penelitian ini dengan tujuan untuk mengetahui bagimana proses yang dilaksanakan oleh humas Bank Indonesia Jawa Barat dalam melaksanakan dan memilih strategi yang tepat dalam memberikan informasi lengkap mengenai ciri-ciri keaslian uang. Penelitian ini menggunakan metode penelitian studi kasus yang berusaha menggambarkan kegiatan melalui pertanyaan penelitian yaitu, pertama bagaimana perencanaan kampanye PR, selanjutnya adalah bagaimana pelaksanaan kegiatan kampanye PR tersebut dan terakhir adalah mengapa humas menjadikan hasil penyebaran informasi sebagai indikator keberhasilan dan evaluasi kegiatan Kampanye ciri-ciri keaslian uang rupiah tahun emisi 2016. Berdasarkan data penelitian kegiatan Kampanye ini melewati berbagai macam tahapan, yang pertama tahap perencanaan yang terdiri dari penentuan anggaran kegiatan,narasumber dan tujuan yang ingin dicapai dalam kegiatan Kampanye tersebut, kedua adalah tahapan pelaksanaan yang diberikan kepada sumber daya yang telah dipilih dan diberikan pelatihan khusus agar saat melakukan kegiatan kampanye dapat memberikan informasi yang menyeluruh, ketiga merupakan proses menilai keberhasilan dan evaluasi kegiatan.

ABSTRACT

Campaign pr it is important to carry out by public relations in an organization, as by these activities organization can introduce a thing with a certain goal. Public relations of bank Indonesia conduct a unique and interesting activity of the PR campaign in an effort to introduce rupiah currency 2016 emission, researcher interested to do this research for the purpose of knowing how the process carried out by public relations officer of Bank Indonesia West Java of implementing and choosing a proper strategy in providing a complete information about the characteristics of the authenticity money. This research uses a study of case method that tries to describe activities through questions of research, first is how to planning pr campaign, next is how the activities of  pr campaign and last is why public relations officer made the results of the information dissemination as an indicator of success and evaluation activities of characteristics the authenticity money rupiah campaign 2016 emission. Based on the research data of this Campaign activity through various phases, the first is the planning phase which consists of determining the budget of activities, the source of information and purpose to be achieved in the activities of campaign, second is the implementing phase given to the selected resources and given special training so when carrying out campaign activities can provide comprehensive information, the third is the process of assessing the success and evaluation of activities
Strategi DKM Masjid Raya PT. Dirgantara Indonesia dalam Optimalisasi Kegiatan Keagamaan
Authors: Hartati Ida , Anwar Saeful , Marfuah Lukluk Atin
Published: May 2021

Penelitian ini bertujuan untuk mengetahui strategi perencanaan, strategi pengorganisasian, dan strategi evaluasi DKM Masjid Raya Habiburrahman PT. Dirgantara Indonesia dalam optimalisasi kegiatan keagamaan. Adapun metode penelitian yang digunakan adalah metode deskriptif dengan pendekatan kualitatif. Pengumpulan data dilakukan dengan menggunakan teknik observasi, studi dokumentasi, wawancara, dan studi kepustakaan. Berdasarkan hasil penelitian di Masjid Raya Habiburrahman, strategi DKM dalam optimalisasi kegiatan keagamaan yaitu dalam strategi perencanaan dilaksanakan dengan membuat rencana kerja yang disebut dengan Garis-garis Besar Haluan Program. Strategi pengorganisasian yang diterapkan adalah dengan melibatkan karyawan PTDI untuk menjadi pengurus DKM. Kemudian strategi evalusi yang diterapkan yaitu melaksanakan rapat evaluasi rutin untuk mengetahui program kerja yang dilaksanakan dan keberhasilan penerapan strategi yang diterapkan. Dalam penelitian ini, dapat disimpulkan bahwa strategi DKM dalam optimalisasi kegiatan keagamaan berhasil diterapkan.

This study aims to determine how the planning strategy, organizing strategy, and evaluation strategy of the DKM Habiburrahman in optimizing religious activities. The research method used is descriptive method with a qualitative approach. In collecting data, it is done by using observation techniques and interviews. Based on the results of research, the DKM strategy in optimizing religious activities, namely in the planning strategy, is implemented by making a work plan called GBHP. The organizing strategy adopted was to involve PTDI employees to become DKM. Then the evaluation strategy that is applied is to carry out routine evaluation meetings to determine the work program of implementing the strategy applied. In this study, DKM strategy in optimizing religious activities was successfully implemented.
Implementasi Fungsi Manajemen pada Kegiatan Sertifikasi Pembimbing Manasik Haji
Authors: Irawati Novita , Setiawan Asep Iwan
Published: May 2021

This article aims to find out an implementasion of management function on the certification of the hajj pilgrims of the VII generation conducted by the hajj pilgrims of west java. The research used descriptive method with qualitative approach. The results showed on the hajj manasik guider certification program in the office of Religion Ministry West Java VII generation. There are managemen activity fungtions such as planning, organizing, mobilization and supervision that implemented well by meeting the standard procedure operational, this means that every process or stage contained in these activities has been implemented quite as well. Plans are done from the administrative stage of activities such as done from the design of activitiy budget, place, resource and material. The organizing organized well. The successful implementasion of management is seen from the implementation of the activity as well. In terms of supervision is done directedly by the team from the ministry of religious of West Java.
Oral food challenge in IgE mediated food allergy in eastern Mediterranean children
Authors: Unsal Hilal , Ozyilmaz Bozat Gokce , Ocak Melike , Akarsu Aysegul , Murat Sahiner Umit , Soyer Ozge , Enis Şekerel Bülent
Published: May 2021

Background: The oral food challenge (OFC) in IgE mediated food allergy causes anxiety both in parents and in patients due to its inherent risks.Objective: Documentation of the rate, spectrum, and predictors of positive reactions is instructive.Methods: Children, who underwent OFC between January 1, 2017 and December 31, 2019 were analyzed.Results: A total of 1361 OFCs in 613 cases were reviewed. Most of them were performed in preschool children (≤2 years 50%) and 55% of them had more than one OFC. Mainly consid-ered food groups were cow’s milk (31.8%), hen’s egg (28.5%), tree nuts (20%), legumes (7%), seeds (4.9%), and wheat (2.7%). The overall OFC positivity was 9.6%, whereas 6.7% with cow’s milk, 4.9% with hen’s egg, 16.1% with tree nuts, 21.6% with wheat, and 32.8% with seeds. The severity scoring revealed grade I (24.4%), II (45.8%), and III (29.7%) reactions. Fifty (38%) cases required epinephrine and four cases required hospitalization. OFCs with sesame seeds (odds ratio [OR]: 7.747, [confidence interval (CI) 95%: 4.03–14.90]), wheat (OR: 3.80, [CI: 1.64–8.84]), and tree nuts (OR: 2.78, [CI: 1.83–4.23]) predicted a positive OFC while a concomitant asthma (OR: 3.61 [CI: 1.27–10.28]) was more likely to elicit anaphylaxis.Conclusion: In OFC practice, priority is given to basic nutritional sources and the most frequent food allergens, where preschool children with multiple sensitizations are the primary subjects. Increased risks of positive reactions with sesame, tree nut, and wheat and increased risk of anaphylaxis with concomitant asthma should be considered while performing OFC.
Treatment with proton pump inhibitors as a cofactor in adverse reactions of patients undergoing oral food immunotherapy
Authors: García Vega Marta , Bellón Alonso Sara , Pérez España Amelia , Quevedo Teruel Sergio José , Fernández Fernández Sonia , Bracamonte Bermejo Teresa , Echeverría Zudaire Luis
Published: May 2021

Background and objectives: Based on previous studies revealing acid-suppression medication as a risk factor for food allergy tolerance induction, we aimed to establish the importance of those findings in patients undergoing oral immunotherapy (OIT).Materials and methods, results: We describe a case series of four patients who underwent milk OIT with a concomitant use of proton pump inhibitor (PPI) medication and who developed anaphylaxis after a known, previously tolerated dose of milk.Conclusions: PPIs may act as a cofactor in patients undergoing OIT, triggering adverse reac-tions, irrespective of the PPI used or the dosage. It would be necessary to separate the admin-istration of drug from food intake.Since OIT is a new form of treatment, long-term adverse events arising from PPI treatment and other possible triggers are still uncertain. Consequently, monitoring of patient must be prolonged over time. Additional investigations on the influence of different drugs in OIT main-tenance phase are required.
Retinol-binding protein 4 and plasminogen activator inhibitor-1 as potential prognostic biomarkers of non-allergic asthma caused by obesity in adolescents
Authors: Leija-Martínez José J. , Patricio-Román Karla L. , Del-Río-Navarro Blanca E. , Villalpando-Carrión Salvador , Reyes-Garay Juan Antonio , Vélez–Reséndiz Juan Manuel , Romero-Nava Rodrigo , Sanchéz-Muñoz Fausto , Villafaña Santiago , Muñoz-Hernández Onofre , Hong Enrique , Ocharan Esther , Huang Fengyang
Published: May 2021

Background: Non-allergic asthma caused by obesity is a complication of the low-grade chronic inflammation inherent in obesity. Consequently, the serum concentrations of adipokines such as retinol-binding protein 4 (RBP4) and plasminogen activator inhibitor-1 (PAI-1) increase. No gold standard molecule for the prediction of non-allergic asthma among obese patients has been identified.Objective: To evaluate RBP4 and PAI-1 as prognostic biomarkers of non-allergic asthma caused by obesity.
Methods: A cross-sectional study between four groups of adolescents: (1) healthy (n = 35), (2) allergic asthma without obesity (n = 28), (3) obesity without asthma (n = 33), and (4) non-aller-gic asthma with obesity (n = 18).Results: RBP4 was higher in the non-allergic asthma with obesity group than in the obesity without asthma group (39.2 ng/mL [95% confidence interval (CI): 23.8–76.0] vs. 23.5 ng/mL [95% CI: 3.2–33.5], p < 0.01), and PAI-1 was higher in the non-allergic asthma with obesity group than in the obesity without asthma group (21.9 ng/mL [95% CI: 15.7–26.5] vs. 15.9 ng/mL [95% CI: 9.4–18.2], p < 0.05). Receiver operating characteristic (ROC) curve analysis demonstrated that the serum RBP4 cut-off value was >42.78 ng/mL, with an area under the ROC curve (AUC) of 0.741 (95% CI: 0.599–0.853, p = 0.001), considered acceptable. The PAI-1 cut-off value was >12.0 ng/mL, with an AUC of 0.699 (95% CI: 0.554–0.819, p = 0.008), considered fair.Conclusions: RBP4 may be useful to predict non-allergic asthma among obese adolescents in clinical practice.
Association of the rs17250932, rs4794067 and rs2240017 polymorphism in the TBX21 gene with autoimmune diseases
Authors: Wang Haili , Wang Hong , Wu Yue , Ling Hua-yun , Wu Ling-ling , Ye Dong-Qing , Wang Bin
Published: May 2021

Objective: To evaluate systematically the association between TBX21 gene polymorphisms (rs17250932, rs2240017, and rs4794067) and the risk of autoimmune diseases in Asian populations. Methods: The Medline, Web of Science, and Chinese Biomedical Literature Database were used to retrieve eligible studies that were published before July 2020. Pooled odds ratios (OR) and 95% confidence intervals (95% CI) were calculated by using the dominant model, heterozygote contrast model, and allelic contrast model. Publication bias was evaluated using contour-enhanced funnel plots and Egger’s regression test. Sensitivity analysis was conducted to assess the robustness of this meta-analysis.Results: A total of 12 eligible studies, including 3834 patients and 4824 healthy controls, were recruited in this meta-analysis. The pooled data demonstrated that TBX21 rs2240017 and rs4794067 polymorphisms were significantly associated with the risk of autoimmune diseases in Asian populations in allelic contrast model (OR: 1.456, 95% CI: 1.131–1.875, P = 0.004; OR: 0.766, 95% CI: 0.615–0.954, P = 0.017), heterozygote comparison model (OR: 1.647, 95% CI: 1.239–2.189, P = 0.001; OR: 0.796, 95% CI: 0.634–0.999, P = 0.049), and dominant model (OR: 1.572, 95% CI: 1.194–2.071, P = 0.004; OR: 0.767, 95% CI: 0.607–0.970, P = 0.027). The G allele of rs2240017 may be a risk factor for autoimmune diseases, and the T allele of rs4794067 may increase the risk of autoimmune diseases. However, we failed to find evidence of the association between TBX21 rs17250932 polymorphism and susceptibility to autoimmune diseases. No publication bias was established in this meta-analysis.Conclusion: This meta-analysis indicated that TBX21 rs2240017 and rs4794067 polymorphism confer susceptibility to autoimmune diseases, but not rs17250932.
Does sugammadex suppress allergic inflammation due to rocuronium in animal model of rat?
Authors: Yeşiltaş Serdar , Nur Orhon Zeynep , Cakır Hasan , Dogru Mahmut , Gura Celik Melek
Published: May 2021

Introduction and Objectives: There are a few reports in the literature about the successful use of sugammadex in the treatment of hypersensitivity reactions caused by rocuronium; however, the pathophysiological mechanism is still unknown. This study aims to investigate the changes caused by rocuronium in the lung and the effect of sugammadex on these changes with bio-chemical, light microscopic and immunohistochemical parameters on a rat model.Materials and Methods: For the study, 28-male Sprague-Dawley rats were randomly divided, seven of each, into four groups. Group C (control) received only 0. 9 % NaCl without any drug. Group R received rocuronium alone 1mg/kg. Group S received sugammadex alone 96 mg/kg. Group RS received rocuronium 1mg/kg and sugammadex 96 mg/kg. After 24 h later, the ani-mals were sacrificed and their tissues were removed. Biochemical (IgE/CRP), light microscopic and immunohistochemical findings were recorded.Results: Immunoglobulin E and CRP levels, peribronchial, alveolar septal lymphocytic infiltra-tion, thickening of the alveolar membranes and bleeding sites in Group R were significantly higher than all the other groups. In Group RS, while these parameters were significantly lower than that of Group R and Group S, it was significantly higher than that of Group C. Total mast cells and tryptase-positive mast cells counts were significantly higher in Group R than in all other groups. In Group RS, these parameters were statistically lower than that of Group R and Group S, but higher than that of Group C.Conclusions: This study shows that allergic inflammatory changes due to rocuronium in the lungs of rats are reduced with sugammadex. These results support cases of anaphylaxis due to rocuronium which improved with sugammadex.
Long-chain non-coding RNA n337374 relieves symptoms of respiratory syncytial virus-induced asthma by inhibiting dendritic cell maturation via the CD86 and ERK pathway
Authors: Sun Shuning , Yao Ming , Yuan Lifen , Qiao Jianou
Published: May 2021

Background: In this study, we investigated the relationship between long-chain non-coding RNAs (lncRNAs) and respiratory syncytial virus (RSV)- exacerbated asthma.

Methods: Transcriptome microarray was used to detect differentially expressed lncRNAs in dendritic cells (DCs) co-cultured with RSV-infected human airway epithelial cells and DCs infected with RSV. The identified downregulation of lncRNA n337374 was validated using fluorescence RT-qPCR. LncRNA n337374-overexpressing DCs and RSV-exacerbated asthmatic mouse models were established. Airway hyperreactivity and bronchoalveolar lavage fluid (BALF) were examined, and pathological changes in lung tissues were observed in mice. Surface molecules in DCs were detected by flow cytometry and RT-qPCR and the expression of CD86 and mitogen-activated protein kinases was determined by western blot.

Results: In an RSV-exacerbated asthmatic mouse model, the airway wall was thickened, luminal stenosis was observed, a large number of inflammatory cells were infiltrated in the lung tissue, lung function was impaired, and counts of inflammatory cells in the BALF were increased. The overexpression of lncRNA n337374 ameliorated these pathological changes and improved impaired lung function and inflammation in an asthmatic mouse model. In DCs co-cultured with RSV-infected human airway epithelial cells, CD86 expression was promoted and ERK was markedly phosphorylated. When lncRNA n337374-overexpressing DCs were used in the co-cultures, the expression of CD86 and phosphorylated ERK was decreased.

Conclusion: The results suggest that lncRNA n337374 overexpression may suppress DC maturation by downregulating the CD86 and ERK pathway, subsequently relieving the symptoms of RSV-induced asthma. LncRNA n337374 may be a promising target in the treatment of RSV infection-induced asthma.
Acute pericarditis: A peculiar manifestation of common variable immune deficiency
Authors: Ramzi Nasim , Yazdani Shahrooz , Talakoob Hamed , Karim Hossein , Jamee Mahnaz , Azizi Gholamreza
Published: May 2021

Common variable immune deficiency (CVID) is known as the most prevalent symptomatic inborn error of immunity associated with autoimmune and inflammatory complications in addition to recurrent infections. In this study, we investigated the prevalence of acute pericarditis as a complication in the past medical history of 337 CVID patients. We found five patients (1.5%) that had experienced acute pericarditis, and described the medical history of three patients.
The Multiple Benefits of Urban Agriculture
Authors: Oldani Camille
Published: May 2021

Urban agriculture has emerged as a solution to food insecurity and other issues faced by underserved communities in urban areas. This study compares four urban food initiatives to highlight differences in implementation and success across different agricultural practices. The study also examines the varying levels of support for these initiatives in the United States and Cuba. The comparison shows that different initiatives within the urban food movement meet a unique intersection of multifaceted societal needs beyond the main goal of hunger alleviation. The main intersecting social needs that urban food initiatives can address are food accessibility, public health, and sustainable development. Moreover, different forms of governmental or non- governmental support for these initiatives influence their success and the scope of their outreach. Broader implications of this study include the importance of utilizing urban food not only as a remedy to hunger and food insecurity problems but also as a way to address public health and sustainable development goals in cities. The main findings imply a necessity for local governments to include urban agriculture initiatives in sustainability and food security plans for cities to encourage sustainable development, health, and increased food access for city residents.
Green Eyes: Corporate Surveillance of Environmental Activists
Authors: Irigoyen Emily
Published: May 2021

This analysis examines contemporary examples of corporate surveillance and offers new questions to guide future research on the role of privacy, social media, and grey intelligence on surveillance of environmental activist groups. In particular, this study explores different cases of activist monitoring, both online and in person, to demonstrate that the increase of activism on social media, while seemingly beneficial, has also made activists more vulnerable to surveillance by corporations because of the public nature of their personal information. The paper also proposes that grey intelligence, which is the phenomena of corporations colluding with former and current government actors to carry out their activist surveillance, is a rising phenomenon that should be the subject of future research. To provide background of these topics, this analysis investigates the various conceptions of privacy and surveillance and discusses how they have been defined previously in both philosophical and legal terms. This section covers how the definition of privacy and the requisites of the US legal system may pose a barrier to activists seeking recourse in the court system for corporate monitoring. This investigation also discusses the drivers of corporate surveillance and connects this phenomenon to reputational capital and corporate strategy literature.
Viable Prediction for Atrial Fibrillation Recurrence After Catheter Ablation
Authors: Baljepally Vinila , Raffa Jesse , Zhao Xiaopeng
Published: May 2021

Introduction: Atrial fibrillation (AF) is the most common heart rhythm abnormality and the leading cause of stroke. Radiofrequency catheter ablation is used to treat AF but recurrence can occur after the ablation procedure, requiring repeat procedure. A new model to predict AF recurrence after ablation was developed through multivariate analysis.
Methods: The variables include demographic, electrocardiographic, echocardiographic, and clinical parameters. In a retrospective review (n=82), 41 patients who underwent repeat ablation for recurrent AF were compared to 41 controls that underwent ablation only once.
Results: Of the analyzed parameters, age, female gender and left atrial enlargement were not predictive, but P wave duration (PWD) and obstructive sleep apnea (OSA) were significant predictors of repeat ablation (p-value = 0.0003 and 0.0023, respectively). Based on the analyses, a simple decision tree model was developed, achieving a prediction accuracy of 87% (sensitivity=83%, specificity=90%).
Conclusion: The developed PWD and OSA 2-predictor model has good accuracy and sensitivity, both of which make it a viable prediction model for AF recurrence after catheter ablation. The developed model will help doctors: 1) Avoid repeat procedure in patients at high risk of recurrence by exploring alternative treatments (2) Reduce costs by avoiding repeat procedure (3) Correct underlying issues prior to procedure in those at high risk (4) Objectively inform patients about recurrence so they can make an informed decision about whether to undergo the procedure. Adopting predictive models such as ours may therefore improve quality care and reduce costs for AF patients undergoing ablation.
Front Matter: Cover Page, Table of Contents, and a Letter from the Editors
Authors: Sastry Skanda K , Jung Jong Eun , Martinez Catherine , Hong Seok Hee
Published: May 2021

After a 5 year hiatus since 2016, we are proud to present Volume 11 of the Vanderbilt Undergraduate Research Journal. Our mission was to showcase the brilliant work of Vanderbilt students from any discipline and we are thrilled to publish this volume after over a year and a half of work. Despite our infancy as an organization, we were grateful to receive 32 submitted manuscripts this year due to the tireless work from our Publicity committee. In this volume, we are pleased to present papers from the Natural Sciences, Social Sciences, Humanities, Political Sciences, and Education, with many papers combining methods of study from different fields.
Mujeres y movimiento negro afromexicano a través de la historia de vida
Authors: Huerta Itza Amanda Varela
Published: May 2021

Resumen: El objetivo de este artículo es describir y analizar el proceso de construcción de una subjetividad política negra-afromexicana a partir de la historia de vida de la activista e intelectual negra-afromexicana Juliana Acevedo (1979). Esta narración se enmarca en el proceso político por el cual algunas mujeres afro construyeron desde 2012 un espacio de enunciación política generizado respecto a la identidad etnizada a finales del siglo XX y XXI en la Costa Chica mexicana. Pretendo dar cuenta de que Acevedo, como un ejemplo de las mujeres activistas e intelectuales, construye su diferencia dentro y fuera del movimiento afrodescendiente en cuanto a las intersecciones de racialización, clase y género para cuestionar las formas históricas y políticas mediante las cuales han sido representadas, así como exponer las marcas del discurso feminista en su narración.
Dormancy-breaking treatments and soil types on Chamaecrista rotundifolia emergence and initial development
Authors: Gomes Josilene do Nascimento , Abreu Natan Lima , Nascimento Angélica Lucélia da Silva , Rocha Sara Muniz , Quadros Barbara Rodrigues de , Faria Letícia de Abreu
Published: May 2021

Abstract Chamaecrista rotundifolia is a legume of high yield and nutritional value for livestock; however, it presents high seed dormancy. The aim of this study was to evaluate dormancy-breaking methods and the influence of soil texture on seedling emergence and initial development of C. rotundifolia. The experiment was performed in a greenhouse in a split-plot design with five replications. There were three treatments including dormancy-breaking techniques with immersion of the seeds in (1) hot water at 80°C for 30 s followed by 12 h in water at room temperature (25 °C; HW); (2) water at room temperature (25 °C) for 24 h (EW); and (3) hydrochloric acid (0.05 mol L-1) for 15 min (HA) (4) and a control group with no seed intervention, disposed in the main plots in randomized blocks. Seeds were cropped in two types of soil as subplots. Seedling emergence was evaluated daily to calculate the percentage emergence and emergence speed index. Plant performance was evaluated (21 days after sowing) through measurements of mass and length of components. Chamaecrista rotundifolia showed a high degree of dormancy in the seeds, and the treatment using HW had greater efficiency in seedling emergence (p < 0.01) and emergence speed index (p < 0.05). Total dry mass was superior in sandy soil (p < 0.05). Soil texture and dormancy treatments influenced the initial performance of plants, which performed better in sandy soil.
Flora fanerogâmica do litoral centro-norte do Rio Grande do Sul, Brasil
Authors: Gonzatti Felipe , Valduga Eduardo , Scur Luciana , Wasum Ronaldo Adelfo
Published: May 2021

Resumo Um inventário de fanerógamas da planície costeira da região centro-norte do Rio Grande do Sul, Brasil é apresentado. Durante dois anos, todas as fitofisionomias dos municípios de Cidreira, Balneário Pinhal e Palmares do Sul foram amostradas. As espécies foram classificadas quanto ao ambiente de ocorrência, hábito preferencial, naturalidade e grau de ameaça. Foram coletadas 383 espécies de 92 famílias, sendo 365 (95%) nativas e 18 (5%) exóticas. As famílias de maior riqueza foram Asteraceae (45), Poaceae (30), Cyperaceae (24) e Fabaceae (23). As formações campestres apresentaram a maior riqueza florística (146), seguidas pelas florestais (132) e lacustres (17). Os hábitos preferenciais foram herbáceo/arbustivo (68%), árvore (20%), trepadeiras (6%), epífitas (6%) e parasitas (1%). Ao todo, foram registradas 18 espécies em alguma categoria de ameaça. Os dados encontrados representam uma alta riqueza de espécies para região sendo compatíveis às estimativas e ao encontrado por outros autores em áreas costeiras, e devem-se basicamente pelo mosaico fitofisionômico e geográfico da região e pela influência dos biomas Mata Atlântica e Pampa. Ameaças à flora local foram evidenciadas, principalmente relacionadas à degradação dos habitats naturais pelos cultivos agrícola e silvícola.
Presumed cytomegalovirus retinitis late after kidney transplant
Authors: Silva Filipa , Ficher Klaus Nunes , Viana Laila , Coelho Inês , Rezende Juliana Toniato , Wagner Daniel , Vaz Maria Lúcia , Foresto Renato , Silva Junior Helio Tedesco , Pestana José Medina
Published: May 2021

Abstract Cytomegalovirus (CMV) retinitis is a rare manifestation of CMV invasive disease and potentially threatening to vision in immunocompromised individuals. Clinical suspicion is fundamental since it is an unusual entity with a progressive and often asymptomatic installation over a long period. The authors report a 70-year-old man with diabetic nephropathy who underwent a kidney transplant (KT) in August 2014 with good clinical evolution. No previous CMV infection or episodes of acute rejection were reported. Five years after transplant, he was admitted due to a reduced visual acuity of the left eye with seven days of evolution with associated hyperemia, without exudate. The ophthalmologic evaluation was compatible with acute necrosis of the retina and presumed associated with CMV infection. He had a progressive improvement after ganciclovir initiation. CMV retinitis is one of the most serious ocular complications in immune-suppressed individuals and can lead to irreversible blindness, and because of that, early diagnosis and treatment remains crucial in obtaining the best visual prognosis in affected patients. Secondary prophylaxis with ganciclovir is not consensual, neither is the safety of reintroducing the antimetabolite in these cases.
Orthodontic treatment pause during COVID-19 outbreak: Are we overlooking potential harms to our patients and their treatment outcomes?
Authors: ABED AL JAWAD Feras , ALHASHIMI Najah
Published: May 2021

ABSTRACT Introduction: The global outbreak of coronavirus disease 2019 (COVID-19) has led all dental governing bodies across the world to minimize or cancel routine/elective dental procedures and limit dental services to only acute emergency situations. Orthodontic treatment is a long-term treatment that necessitates several appointments. However, if patients are left unsupervised during this pandemic, serious harms might arise apart from acute orthodontic emergencies. Objective: In this article we highlight these harms and their negative impact on patients and the overall success of their treatment. Conclusion: We briefly presented actions needed to be undertaken by orthodontists to gradually allow for recalling patients according to the stage of their treatment to avoid any potential harms to the treatment outcome and avoid any subsequent medicolegal consequences.
DOCENTES EN FORMACIÓN: REFLEXIONES SOBRE SU PRÁCTICA EN SITUACIONES REALES DE TRABAJO EN LA ESCUELA SECUNDARIA
Authors: Gutiérrez Álvarez Edith
Published: May 2021

Actualmente, los estudiantes normalistas de la Ciudad de México que cursan el último ciclo de su formación como docentes para la escuela secundaria, llevan a cabo sus prácticas docentes encarando situaciones reales de trabajo, donde la docencia reflexiva se convierte en uno de los pilares fundamentales. El objetivo del presente artículo es analizar las situaciones problemáticas, las actividades que ponen en marcha para darles solución y las reflexiones que se derivan de tales experiencias. La investigación que dio origen al artículo toma en cuenta la propuesta del método biográfico-narrativo. Adopta como instrumento de acopio de información las narrativas documentadas por cuatro estudiantes normalistas en sus respectivos documentos recepcionales; ahí relatan sus conflictos y reflexiones sobre las experiencias adquiridas durante su interacción en las aulas de una escuela secundaria, lo que constituye un estudio de caso, con cuatro unidades de análisis. Los resultados reflejan procesos reflexivos que van desde llamados de apoyo que apuntan hacia la constitución de equipos de trabajo para concentrarse en tareas de colaboración, hasta realidades cotidianas y tensiones que se desencadenan entre los actores del proceso de enseñanza aprendizaje.
Making a film to share traditional engineering techniques to tackle the global water crisis
Authors: Bingham Louise , Hetherington David
Published: May 2021

Civil engineers in the UK have teamed up with a water charity to make an educational film that helps communities in semi-arid climates manage their water. The team learnt how to construct simple dams, known in India as ‘johads’, that harvest seasonal rainfall, reducing flood and drought risk. They then built a new dam and restored another in Rajasthan district, recording the process to enable others to replicate the work. A language-neutral educational film was then produced and tested with other communities in India and Colombia to ensure applicability to a variety of geographies, cultures and environments. Educating communities on water management in this way will help to achieve the United Nations sustainable development goal 6: clean water and sanitation for all.