bluuebunny/crossref_metadata_2025 huggingface dataset:
Electric vehicle wireless charging system for the foreign object detection with the inducted coil with magnetic field variation
Authors: Alshammari Abdulaziz , Chabaan Rakan C.
Published: October 2023

Foreign object detection is one of the most critical issues in electric vehicle wireless charging systems. This article proposes a foreign object detection scheme with an induced coil in the charging system. The proposed method uses a multifunctional tunneling resistance sensor matrix to detect the presence of a foreign metal object between the coils. An asymmetrical induction coil design scheme is proposed to eliminate the blind area. The suggested method utilizes size-modulated c-shaped coil units to remove invisible zones that result from the magnetic field’s axial uniformity. The induced voltage in the transmission coil is measured using ANSYS/MAXWELL software. The experimental results show that the suggested method has a number of benefits over regular even-sensing coils, including higher uniformity in the induced current, position-dependent detection sensitivity, and detection accuracy. It provides a feasible and affordable way to get around the drawbacks of the traditional detecting coil.
Investigating effects of Lorentz forces and convective heating on ternary hybrid nanofluid flow over a curved surface using homotopy analysis method
Authors: Lone Showkat Ahmad , Allehiany F. M. , Anwar Sadia , Shahab Sana , Saeed Anwar , Eldin Sayed M.
Published: October 2023

This work investigates the ternary hybrid nanofluid flow over an extending curved surface. The surface is impermeable and convective with hot working fluid water. Additionally,

TiO

2

{\text{TiO}}_{\text{2}}

,

CoFe

2

O

4

{\text{CoFe}}_{\text{2}}{\text{O}}_{\text{4}}

, and

MgO

\text{MgO}

nanoparticles are suspended with water to form a tri-hybrid nanofluid. The modeled equations are presented in the partial differential equation form and are then converted to ordinary differential equations with appropriate similarity variables. The semi-analytical solution is determined by homotopy analysis method. The impacts of magnetic field, Joule heating, chemical reaction, Brownian motion, and thermophoresis on flow profiles, Nusselt number, and Sherwood number are determined using tables and figures. The findings of this study demonstrated that as the magnetic parameter upsurges, the velocity distribution shrinkages, while the temperature distribution escalates. The greater curvature factor boots the velocity, thermal, and volumetric fraction distribution. The thermal and volumetric fraction distributions are the increasing functions of thermophoresis factor. The higher magnetic factor, Eckert number, and thermal Biot number increase the Nusselt number, while they reduce the higher Brownian and thermophoretic factors. The higher thermophoresis and Brownian motion factors heighten the Sherwood number. Furthermore, it has been noted that using nanofluid (TiO2-water) and hybrid nanoliquid (TiO2-CoFe2O4/water), the transfer of energy rate increases by up to 17.31 and 31.72% as the nanoparticle parameter increases from 0.01 to 0.04, respectively. However, the energy transference rate in case of ternary hybrid nanoliquid (TiO2-MgO-CoFe2O4/water) is 47.972%.
Thermo-solutal Marangoni convective Darcy-Forchheimer bio-hybrid nanofluid flow over a permeable disk with activation energy: Analysis of interfacial nanolayer thickness
Authors: Mohanty D. , Mahanta G. , Byeon Haewon , Vignesh S. , Shaw S. , Khan M. Ijaz , Abduvalieva Dilsora , Govindan Vediyappan , Awwad Fuad A. , Ismail Emad A. A.
Published: October 2023

The Marangoni convective phenomena have a unique impact on industries and medical tools. These phenomena are more prominent in the presence of dual nanoparticles (NPs) over base fluids such as blood that are surrounded by a thin interfacial nanolayer, an important feature to control the physical and thermal properties of the NP. In this problem, we have analysed the thermo-solutal Marangoni convective Darcy-Forchheimer flow of nanomaterials with the impact of the interfacial nanolayer. The results of the system of an exponential heat source, non-linear radiation, joule heating, and activation energy are discussed. An appropriate transition is applied to rationalise the substantially paired and nonlinear governing equations and then processed by the Galerkin finite element method (G-FEM). The impression of different governing parameters on the governing systems in conjunction with entropy and Bejan number is demonstrated through graphical and tabular form. Graphs are drawn with an evaluation of general and hybrid nanofluids (HNFs) and different nanolayer thicknesses of NPs. Activation energy and chemical reaction parameters restrict the Sherwood number, and the same is observed for the Nusselt number with an increase in the Brinkman and Eckert numbers. The thickness of the interfacial nanolayer of the NPs restricts the entropy generation of the system, while the entropy is higher for the HNF than the nanofluid. An opposite feature was observed for the Bejan number.
FTO génpolimorfizmus, obezitás, 2-es típusú cukorbetegség és rákkockázat viszonya. Onkodiabetológiai összefüggések
Authors:   ,   PTE ETK Egészségtudományi Doktori Iskola, Bánhegyi Róbert János
Published: October 2023

Alaphipotézisem szerint az elhízás, a 2-es típusú diabetes és a malignus daganatok epidemiológiája, metabolizmusa, genetikai háttere számtalan ponton kapcsolódik, ami terápiás konzekvenciával jár. Első vizsgálatunkban az obezitáshoz közvetlenül, a cukorbetegséghez közvetve asszociált FTO génpolimorfizmus tápanyagkínálat függvényében változó kockázati szerepét igyekeztünk meghatározni az elhízásra és a 2-es típusú diabetesre vonatkozóan. Eredményeink alapján a tápanyagbevitellel korreláló, magasabb éhomi vércukor- és trigliceridszint az FTO genotípusától függően befolyásolja a szervezet zsírraktározását, ezáltal elhízáshoz vezethet, ami a diabetes nagyobb rizikójával járhat. Második vizsgálatunkban onkológiai betegeken elemeztük a glikémiás és tápláltsági állapot kapcsolatát a tumorprogresszióval, illetve a metformin rákellenes effektusát igyekeztünk megerősíteni. Kutatásunkban igazoltuk, hogy áttétes stádiumban a glikémiás kontroll általában rosszabbodik, illetve magasabb vércukorszint esetén gyakrabban jelentkezhet metasztázis. A vizsgált populációban 23,28%-ban észleltünk obezitást és 20,34%-ban diabetest. Primer májsejtes, hasnyálmirigy-, húgyhólyag-, prosztata- és endometrium-karcinóma, valamint posztmenopauzális emlőrák esetében ennél is nagyobb diabetes-arányt találtunk. Metasztázis a metformin alkalmazása mellett fordult elő legritkábban. Az alaphipotézist mindkét vizsgálatunk alátámasztotta, ami újabb bizonyítékként szolgálhat a diabeteses rákbetegek komplex terápiájának jelentőségére.
Revealing observatory networks through object stories: Introduction
Authors: Higgitt Rebekah
Published: October 2023

This paper introduces a group of three articles that bring together object stories relating to observatory history and networks. The three articles (‘Instrumental networks’, ‘Object itineraries’ and ‘Observatory audiences’) each bring together three object stories by different authors that contribute to the article theme. Here the genesis of the collection at the workshops of the Observatory Sites and Networks project is discussed, along with the approaches taken and the kind of insights that studies of material culture can shed on histories of observatories and the observatory sciences. The arrangement of the stories into three themes is outlined while common threads and recurring motifs that create connections and synergies across the thematic sections are highlighted. Together the collected papers make an argument for the use of objects in research, demonstrating the fruitfulness of investigating their histories and showing how they can expand our understanding of the networks of people, organisations and objects that were interested in or essential to the successful functioning of observatories. They also demonstrate the breadth and variety of interests and resources that were drawn into these networks, offering new ways of understanding and interpreting both observatory sites and museum objects.
Revealing observatory networks through object stories: Instrumental networks
Authors: Akkermans Emily , Wilder Kelley , Thompson Samantha
Published: October 2023

This paper presents three pieces that use objects, or object types, to reveal the material, personal, institutional and commercial networks that surrounded the introduction and successful use of instruments, systems and techniques. The objects explored are: the Hourly Signal Relay, used within the time signal system of the Royal Observatory, Greenwich, from the mid-nineteenth century; photographic glass plates from the British 1874 transit of Venus expeditions; and an electronic imaging tube, Lallemand’s camera, developed in Paris and used at the Lick Observatory in California in the 1960s. Each story uses examples of failure as a means of highlighting a lack of robustness in or effort required to maintain these networks. Once created, however, such networks could, as the second two stories note, go on to develop and support alternative approaches, helping to create success from apparent failure. Nevertheless, complexity, failure and fragility have also led to the underrepresentation or obscurity of these objects in museum collections, until given focused attention in these studies. The paper forms part of a collection of articles: Revealing observatory networks through object stories. The other papers in the collection are ‘Object itineraries’, and ‘Observatory audiences’ and the genesis of the collection is discussed in the ‘Introduction’.
Tinkering with nature: craft, domesticity and female labour in F Percy Smith’s ‘Data’ notebooks (1925–1944)
Authors: Long Max
Published: October 2023

This article examines two notebooks belonging to the scientific filmmaker F Percy Smith, labelled ‘Data A’ and ‘Data B’, which are held at the National Science and Media Museum (NSMM) in Bradford. These notebooks offer valuable insights into Smith’s working process in the last two decades of his life – between 1925 and 1945 – and they detail the wide array of materials, tools and equipment that he used to produce his films. The article suggests some of Smith’s uses for the notebooks, such as noting down locations for collecting specimens or describing how to construct tanks and troughs for filming individual organisms. Using a wide range of supplementary sources, including images, videos and an interactive map, I argue that Smith’s work amounted to a form of scientific ‘craft’, which blended across his experimentation with photographic media and scientific observation. Dismantling the long-held belief that F Percy Smith worked entirely alone, the article uses the notebooks as an opportunity to highlight for the first time the role that two women played in Smith’s studio-laboratory: his wife, Kate Smith, and his assistant, Phyllis Bolté. The notebooks are a key source for understanding the production of natural history films of the interwar period, including the popular Secrets of Nature (1922–1933) series. The article reflects on what media scholars can learn from taking a closer look at the materials and methods used for making films of this kind.
Photography and electroplate in 1840s Birmingham
Authors: Gane Jo
Published: October 2023

Industrial improvements to silver plating through the work of electroplating firms such as Elkington, Mason and Co are an important part of our industrial heritage, bridging art, science and industry to form a significant portion of museum collections. However, the impact of this development of silverplating technology upon photography has not previously been explored. This article details the improvements that electroplated silver brought to the daguerreotype photographic process and to the manufacture of daguerreotype plates in Birmingham, offering a material reappraisal of the inventive qualities of the daguerreotype within a wider narrative of industrial manufacture. Chemists in 1840s Birmingham were developing photographic techniques and silverplating processes at the Birmingham Royal School of Medicine and Surgery, later Queens College on Paradise Street. These scientists – George Shaw (1818–1904) and John Percy (1817–1889) – had detailed, tactile knowledge of the convergent chemistry and processes in both arenas. Developments in the industrial manufacture of silverplate in 1840s Birmingham created significant improvements to the materials used in the daguerreotype photographic process, making photography more viable as a commercial venture. Shaw planned an early portrait studio and worked with early innovators in electroplating techniques the Marrian brothers (Francis (1802–1893) and Benjamin James Pratt Marrian (1811–1891)) using magneto-plate technology developed by another Birmingham industrial entrepreneur John Woolrich (c. 1791–1843). This potential studio did not emerge due to restrictive patenting and licensing restrictions around the practice of daguerreotype photography, yet extant daguerreotypes tell a story of improvements stemming from technical innovation. These daguerreotypes situate industrial Birmingham as a place of innovation and invention and place the daguerreotype photographic process within narratives of industrial improvements and radically inventive manufacturing practices. Key to the analysis presented here is the role of the recreation of historic techniques in historical research and the value of acquiring tactile knowledge of the behaviour of materials during the processes explored. Here practical experiments allowed the author to look beyond the surviving daguerreotypes via material knowledge to the circumstances and social environment of production. This approach revealed new knowledge which offers an alternative reading of the history of objects through their materials.
A. C. SPONVİLLE'İN AHLAK ANLAYIŞI, KAMU YÖNETİMİNDE ETİK İLKELER VE ÇALIŞMA AHLAKI
Authors: EKEN İhsan
Published: October 2023

Etik ve ahlak, birbirleri ile karıştırılan, aralarında doğrudan ilişki bulunan fakat farklı anlamlara sahip kavramlardır. Her ikisi de hayatın her alanında olduğu gibi çalışma alanında da gerekli olan ve başvurulan iki olgudur. Kamu yönetimi ve kamu yöneticileri açısından hakkaniyetle uygulandığı durumlarda kamu yönetimini birçok olumsuz yönlerinden arındırabilecek niteliğe sahiptirler. Kuşkusuz bu alanda belirlenmiş ve uygulamaya konmuş bir çok kriter ve ilke de bulunmaktadır. A.C. Sponville, etik ve ahlak konularına farklı bir felsefi bakış açısı ile yaklaşmıştır. “Ahlakın evrensel yalnızlığı” kavramı ile ahlakın bireyselliğini vurgulamıştır. Her ne kadar çeşitli prensipler, kurallar ve cezalar düzenlenmişse de ahlak açısından belirleyici olanın insan olduğunu vurgulamıştır. Kamu yönetimi alanında da bu bakış açısı göz önünde bulundurularak, insana odaklanılması ve ahlakın zorunluluklardan değil içten gelen bir istekle uygulanması durumunda daha etkili olunacağı düşünülmektedir. Çalışmada A.C.Sponville’in ahlak anlayışı çerçevesinde, kamu yönetiminde etik ve çalışma ahlakı sorunu irdelenmiştir. Çalışma neticesinde, var olan etik kodlara ve yasal düzenlemelere rağmen, çalışanların sahip olduğu bireysel ahlaki yapının, çalışma ahlakında belirleyici temel unsur olduğu görüşüne varılmıştır. Çalışmada betimsel analiz ve metin analizi yöntemlerinden yararlanılmıştır.
Dynamic Changes in Local Activity and Network Interactions among the Anterior Cingulate, Amygdala, and Cerebellum during Associative Learning
Authors: Halverson Hunter E. , Kim Jangjin , Freeman John H.
Published: October 2023

Communication between the cerebellum and forebrain structures is necessary for motor learning and has been implicated in a variety of cognitive functions. The exact nature of cerebellar–forebrain interactions supporting behavior and cognition is not known. We examined how local and network activity support learning by simultaneously recording neural activity in the cerebellum, amygdala, and anterior cingulate cortex while male and female rats were trained in trace eyeblink conditioning. Initially, the cerebellum and forebrain signal the contingency between external stimuli through increases in theta power and synchrony. Neuronal activity driving expression of the learned response was observed in the cerebellum and became evident in the anterior cingulate and amygdala as learning progressed. Aligning neural activity to the training stimuli or learned response provided a way to differentiate between learning-related activity driven by different mechanisms. Stimulus and response-related increases in theta power and coherence were observed across all three areas throughout learning. However, increases in slow gamma power and coherence were only observed when oscillations were aligned to the cerebellum-driven learned response. Percentage of learned responses, learning-related local activity, and slow gamma communication from cerebellum to forebrain all progressively increased during training. The relatively fast frequency of slow gamma provides an ideal mechanism for the cerebellum to communicate learned temporal information to the forebrain. This cerebellar response-aligned slow gamma then provides enrichment of behavior-specific temporal information to local neuronal activity in the forebrain. These dynamic network interactions likely support a wide range of behaviors and cognitive tasks that require coordination between the forebrain and cerebellum.

SIGNIFICANCE STATEMENTThis study presents new evidence for how dynamic learning-related changes in single neurons and neural oscillations in a cerebellar–forebrain network support associative motor learning. The current results provide an integrated mechanism for how bidirectional communication between the cerebellum and forebrain represents important external events and internal neural drive. This bidirectional communication between the cerebellum and forebrain likely supports a wide range of behaviors and cognitive tasks that require temporal precision.
Accentuated Paralimbic and Reduced Mesolimbic D2/3-Impulsivity Associations in Parkinson's Disease
Authors: Stark Adam J. , Song Alexander K. , Petersen Kalen J. , Hay Kaitlyn R. , Lin Ya-Chen , Trujillo Paula , Kang Hakmook , Collazzo Jenna M. , Donahue Manus J. , Zald David H. , Claassen Daniel O.
Published: October 2023

Impulsivity is a behavioral trait that is elevated in many neuropsychiatric disorders. Parkinson's disease (PD) patients can exhibit a specific pattern of reward-seeking impulsive-compulsive behaviors (ICBs), as well as more subtle changes to generalized trait impulsivity. Prior studies in healthy controls (HCs) suggest that trait impulsivity is regulated by D2/3autoreceptors in mesocorticolimbic circuits. While altered D2/3binding is noted in ICB+PD patients, there is limited prior assessment of the trait impulsivity–D2/3relationship in PD, and no prior direct comparison with patterns in HCs. We examined 54 PD (36 M; 18 F) and 31 sex- and age-matched HC (21 M; 10 F) subjects using [18F]fallypride, a high-affinity D2/3receptor ligand, to measure striatal and extrastriatal D2/3nondisplaceable binding potential (BPND). Subcortical and cortical assessment exclusively used ROI or exploratory-voxelwise methods, respectively. All completed the Barratt Impulsiveness Scale, a measure of trait impulsivity. Subcortical ROI analyses indicated a negative relationship between trait impulsivity and D2/3BPNDin the ventral striatum and amygdala of HCs but not in PD. By contrast, voxelwise methods demonstrated a positive trait impulsivity–D2/3BPNDcorrelation in ventral frontal olfactocentric-paralimbic cortex of subjects with PD but not HCs. Subscale analysis also highlighted different aspects of impulsivity, with significant interactions between group and motor impulsivity in the ventral striatum, and attentional impulsivity in the amygdala and frontal paralimbic cortex. These results suggest that dopamine functioning in distinct regions of the mesocorticolimbic circuit influence aspects of impulsivity, with the relative importance of regional dopamine functions shifting in the neuropharmacological context of PD.

SIGNIFICANCE STATEMENTThe biological determinants of impulsivity have broad clinical relevance, from addiction to neurodegenerative disorders. Here, we address biomolecular distinctions in Parkinson's disease. This is the first study to evaluate a large cohort of Parkinson's disease patients and age-matched healthy controls with a measure of trait impulsivity and concurrent [18F]fallypride PET, a method that allows quantification of D2/3 receptors throughout the mesocorticolimbic network. We demonstrate widespread differences in the trait impulsivity–dopamine relationship, including (1) loss of subcortical relationships present in the healthy brain and (2) emergence of a new relationship in a limbic cortical area. This illustrates the loss of mechanisms of behavioral regulation present in the healthy brain while suggesting a potential compensatory response and target for future investigation.
Having a Positive Attitude or Doing Good Deeds? An Experimental Investigation of Poker Players’ Responses to the Gambling Fallacies Measure
Authors: Newall Philip , Torrance Jamie
Published: October 2023

Gambling fallacies are irrational beliefs about how gambling works, which are common among disordered gamblers, and measured by questionnaires such as the Gambling Fallacies Measure (GFM). Less is known about the potentially rational cognitions of some skilled gamblers, such as professional poker players. The present research experimentally manipulated item 5 from the GFM, “A positive attitude or doing good deeds increases your likelihood of winning money when gambling”, by comparing two new versions focusing only on a “positive attitude” or “doing good deeds” to the original version (control). Item 5 is scored so that “disagree” is the non-fallacious correct answer, but it was hypothesized that the words “a positive attitude” might increase rates of poker players selecting “agree” in a non-fallacious manner. Online experiments were conducted on samples of professional poker players (N = 379), and a broad sample of poker players with no inclusion criteria (N = 1,510). Participants’ responses to item 5 were associated with the rest of their GFM scores (GFM-9). Participants in both samples were more likely to disagree with the good deeds version, and less likely to disagree with the positive attitude version, compared to control. In comparison to the other conditions, good deeds responses were most strongly associated with GFM-9 scores among professionals, while positive attitude responses were least strongly associated with GFM-9 scores among the broad sample. The good deeds version of item 5 has advantageous measurement properties among professional poker players. New approaches are needed to better understand the potentially rational cognitions of skilled gamblers.
Canalisation and plasticity on the developmental manifold of Caenorhabditis elegans
Authors: Jordan David J , Miska Eric A
Published: October 2023

How do the same mechanisms that faithfully regenerate complex developmental programmes in spite of environmental and genetic perturbations also allow responsiveness to environmental signals, adaptation and genetic evolution? Using the nematode Caenorhabditis elegans as a model, we explore the phenotypic space of growth and development in various genetic and environmental contexts. Our data are growth curves and developmental parameters obtained by automated microscopy. Using these, we show that among the traits that make up the developmental space, correlations within a particular context are predictive of correlations among different contexts. Furthermore, we find that the developmental variability of this animal can be captured on a relatively low‐dimensional phenotypic manifold and that on this manifold, genetic and environmental contributions to plasticity can be deconvolved independently. Our perspective offers a new way of understanding the relationship between robustness and flexibility in complex systems, suggesting that projection and concentration of dimension can naturally align these forces as complementary rather than competing.
From qualitative to quantitative: the state of the art and challenges for plant synthetic biology
Authors: Tian Chenfei , Li Jianhua , Wang Yong
Published: October 2023

The flourishing plant science promotes the exploding number of data and the expansion of toolkits. Plant synthetic biology is still in its early stages and requires more quantitative and predictable study. Despite the challenges, some pioneering examples have been successfully demonstrated in model plants.

Backgrounds

As an increasing number of synthetic switches and circuits have been created for plant systems and of synthetic products produced in plant chassis, plant synthetic biology is taking a strong foothold in agriculture and medicine. The ever‐exploding data has also promoted the expansion of toolkits in this field. Genetic parts libraries and quantitative characterization approaches have been developed. However, plant synthetic biology is still in its infancy. The considerations for selecting biological parts to design and construct genetic circuits with predictable functions remain desired.

Results

In this article, we review the current biotechnological progresses in field of plant synthetic biology. Assembly standardization and quantitative approaches of genetic parts and genetic circuits are discussed. We also highlight the main challenges in the iterative cycles of design‐build‐test‐learn for introducing novel traits into plants.

Conclusion

Plant synthetic biology promises to provide important solutions to many issues in agricultural production, human health care, and environmental sustainability. However, tremendous challenges exist in this field. For example, the quantitative characterization of genetic parts is limited; the orthogonality and the transfer functions of circuits are unpredictable; and also, the mathematical modeling‐assisted circuits design still needs to improve predictability and reliability. These challenges are expected to be resolved in the near future as interests in this field are intensifying.
Avances en el desarrollo de la lengua escrita de los pueblos yine, shipibo y ashaninka
Authors: Alonzo Sutta Alicia
Published: October 2023

En los últimos dos años, los hablantes de las lenguas yine, shipibo y ashaninka han decidido proponer alfabetos que representen a su lengua oral en forma escrita, con el fin de que se elaboren materiales educativos para las escuelas bilingües.
Yatiribeitani tsamiri: “el paujil cuando era una persona”
Authors: Cabello Chiricente Caleb
Published: October 2023

En la cosmovisión ashaninka se considera que al inicio de los tiempos, la tierra estuvo poblada por ashaninkas, los que luego se transformaron en animales. Este es un relato que antiguamente narraban nuestros abuelos. El paujil (ave) antes era una persona, que vivía en la cima del monte juntamente con sus familiares en una casa. Cierto día un ashaninka descubre el lugar donde el paujil bebe y a partir de entonces se establece el contacto con el hombre que era paujil. En la conversación entre el paujil y el cazador ashaninka, este último le solicita que ya no provoque más daño a los ashaninkas. Al despedirse, el ashaninka recibió una pituca (tubérculo) de regalo, la que al llegar a su casa se convirtió en un paujil.
Comprensión de oraciones con cláusulas relativas en niños de 6 a 11 años hablantes del español rioplatense
Authors: Zamora Dolores , Barreyro Juan-Pablo , Sánchez María-Victoria , Martínez-Cuitiño Macarena
Published: October 2023

La comprensión de oraciones relativas ha sido el objeto de numerosas investigaciones en la población infantil, pero pocas logran establecer la etapa en la que se adquieren y los estudios en español son escasos. El objetivo de esta investigación es comparar el desempeño de niños hablantes de español rioplatense en la comprensión de oraciones relativas. Para ello, 105 niños de tres grupos etarios: 6-7, 8-9 y 10-11 años, respectivamente, fueron evaluados una tarea de comprensión oral de oraciones relativas de sujeto y de objeto. Los resultados muestran diferencias significativas en el rendimiento de los grupos. Los niños de todas las edades tienen dificultades para comprender oraciones relativas de objeto, mientras que el desempeño en  oraciones relativas de sujeto varía según la posición en la que se encuentra incrustada la cláusula subordinada.
Variación léxica en la aplicación Whatsapp en estudiantes castellanohablantes de educación secundaria
Authors: Castillo Reyes Analí Corina
Published: October 2023

En el mundo de la virtualidad en que estamos inmersos, encontramos diversidad de grupos virtuales que para facilitar la comunicación entre ellos crean su propio lenguaje simplificado. Este lenguaje simplificado, lo encontramos en los grupos virtuales conformados por los estudiantes de secundaria. El presente trabajo tiene como objetivo identificar los tipos de simplificación más usados en esta aplicación por estudiantes de secundaria. El presente documento tiene como objetivo identificar los tipos de simplificación más empleados en esta aplicación por estudiantes de secundaria. La investigación es de tipo cualitativo. El corpus de la investigación se basa en dos grupos virtuales, Experimento y Barrio, de los cuales se recopilaron 52 conversaciones. El estudio concluye que hay tres tipos de simplificación de unidades lingüísticas y la más predominante es la elisión de vocales en el interior de la palabra. Para explicar e interpretar los datos, se aplicará el enfoque variacionista.
How Do Teachers Differentiate Instruction Through Materials in a Colombian Rural Zone?
Authors: Castiblanco Valentina , Pelaez Laura , Santana Melany , Tibaná Danna
Published: October 2023

This research study aims to investigate how teachers implement strategies of  differentiated instruction through materials in their classrooms by taking into consideration the diverse students’ profiles. In this phenomenological qualitative article a total of six (6) EFL educators from Pensilvania (Caldas) participated in this investigation, and data was collected through class observations and semi-structured interviews. The results explore the teachers' level of understanding about differentiation, the training they had received on materials' development and the variety of resources provided for each institution, the aspects they contemplate when creating/designing and adapting materials, and the way in which differentiation through materials was carried out in the classroom. In the conclusion of the article, the importance of providing teachers with the necessary resources is emphasized, as well as the necessity for professional development opportunities, and ongoing support to help them meet the student’s needs.
Outcomes of Surgical Treatment for Localized Tenosynovial Giant-Cell Tumor of the Foot and Ankle: A Case Series
Authors: Ipponi Edoardo , Ruinato Alfio Damiano , Lombardi Leonardo , Cordoni Martina , De Franco Silvia , D'Arienzo Antonio , Andreani Lorenzo
Published: October 2023

Background: Giant cell tumor of the tendon sheath (GCTTS), also termed Tenosynovial giant cell tumor (TGCT), is a locally aggressive tumor which originates from tendon sheaths or bursas. Around 3–5% of these tumors arise from foot and ankle. Localized lesions in this area are often manifested as firm masses or nodules with slow but continuous progression through months and years. Pain associated with weight-bearing, as well as limitations in joint motions, may be reported, depending on tumor’s location. Surgery is the treatment of choice for the definitive removal of GCTTSs with the aim to eradicate the neoplasm and restore the lower limb’s functionality.Methods: Thirteen cases suffering from GCTTS of the foot and ankle underwent surgical resection at our institution between 2017 and 2022. For each case we recorded pre-operative and post-operative symptoms, as well as their pre-operative and post-operative functional status according to both MSTS and AOFAS scores. Eventual complications and local recurrences were reported.Results: Each patient experienced an at least mild pain before surgical treatment. The mean pre-operative MSTS and AOFAS scores were 22.8 and 70.7, respectively. The mean tumor size was 17.7 mm. Each patient received a resection with wide margins. Two cases (15.4%) had local recurrences. None had major complications at their latest follow-up. After the surgery, the mean post-operative MSTS and AOFAS scores increased to 28.3 and 92.2, respectively.Conclusion: Resection with wide margins for foot and ankle GCTTS is effective in restoring the patients’ lower limb functionality and is associated with reasonable local recurrence rates.
Riemann–Hilbert boundary value problem for multidimensional elliptic systems of equations
Authors: Paliokas Eugenijus
Published: October 2023

Multidimensional analogues of Cauchy–Riemann quations and of Riemann–Hilbert boundary value problem are studied. Their relation to the scalar boundary value problem is demonstrated.
Platonic Politics of Moderation and Contemporary Civic Theory
Authors: Bartninkas Vilius
Published: October 2023

This paper examines Plato’s later model of civic participation in relation to contemporary civic theories. It argues that, although the Platonic model satisfies such common criteria for civic theories as equality, autonomy, and empowerment, the key concept to understand this project is moderation. It is moderation that structures and unifies the constituent elements of this model (the rule of law, the persuasion of the preambles, the empowering economy and education). It also explains what kind of personal disposition is central to achieving a stable and rational political order.
Leaving the Dream Behind: Why the Metaphysics of Consciousness cannot be Unveiled by Conceivability Arguments
Authors: Murillo-Lara Luis Alejandro
Published: October 2023

In this paper, I present a novel objection to Chalmers’s “master argument” against the privileged strategy of ‘type B’ physicalists to account for the explanatory gap (the “phenomenal concepts strategy”). Specifically, I argue that the second horn of the master argument gets wrong why zombies cannot have our epistemic situation with regard to consciousness. Zombies cannot have a kind of mental state that we have. If something must have all of our psychological attributes to share our epistemic situation, then zombies cannot serve the purpose of the second horn of the dilemma. By way of background, I begin by briefly outlining a related argument against physicalism, also advanced by D. Chalmers – the “conceivability argument.” I highlight some of the primary challenges with this argument and present additional criticisms. Finally, through a brief examination of panprotopsychism, I consider what lies ahead if Chalmers’s arguments are conceded. I conclude that the phenomenal concept strategy is a sound explanation for why the conceivability of zombies likely does not imply their metaphysical possibility.
Mask Detection App Uses Haar Cascade and Convolutional Neural Network to Alert Comply with Health Protocols
Authors: Rahmad Cahya , Nurfaidah Nurfaidah , Adhisuwignjo Supriatna , Hani’ah Mamluatul
Published: October 2023

This study aims to identify the face of a person whether wearing a mask or not wearing a mask accompanied by an appeal to the importance of wearing a mask. The contribution of this paper to science is to provide an overview of the results of accuracy, precision, recall used by the method used with data that can be accessed by many people, so that it can be developed further or can be compared. This system uses two techniques, namely the classification of whether a person is wearing a mask or not using the Convolutional Neural Network (CNN) model. The architecture used is DenseNet-12 to detect human face objects. The data used has a total of 2332 data sets, 200 of which were retrieved manually as research objects, and the rest were obtained from Kaggle. All data is evaluated using the camera in real-time. The test results show that testing scenario one has the highest score with an accuracy of 85% while testing scenario two gets results of 80%, the precision value in testing scenario one gets results of 75%, and testing scenario two has results of 88%. Scenarios 1 and 2 also have the same recall value of 100%. Based on the data analysis, it can be concluded that the use of the Haar Cascade approach and the Convolutional Neural Network with the DenseNet-121 architecture produces good performance in the case of real-time detection of masked and non-masked facial objects.
Inhibitory effect of theaflavin-3,3′-digallate can involve its binding to the “stem” domain of α-hemolysin of Staphylococcus aureus
Authors: Goc Anna , Sumera Waldemar , Rath Matthias , Niedzwiecki Aleksandra
Published: October 2023

Infections caused by Staphylococcus aureus are currently a worldwide threat affecting millions of individuals. The pathogenicity of S. aureus is associated with numerous virulence factors, including cell surface proteins, polysaccharides, and secreted toxins. The pore-forming α-hemolysin, known as α-toxin, is produced by nearly all virulent strains of S. aureus and is implicated in several diseases including skin and soft tissue infections, atopic dermatitis, and pneumonia. There are currently no vaccines available for the prevention of S. aureus infections and the efficacy of available antibiotics has been fading. In this study we examined the mode of antihemolytic activity of theaflavin-3,3′-digallate against α-hemolysin of methicillin-resistant S. aureus by molecular docking using AutoDock Vina as the molecular docking tool. The theaflavin-3,3′-digallate docked the molecular sequence of the Hla (PDB ID:7ahl). The scores of the top 10 binding modes obtained were between −9.0 and −8.5 kcal mol−1, and the best binding mode was −9.0 kcal mol−1. Direct binding sites of theaflavin-3,3′-digallate to the “stem” domain of Hla were revealed which primarily targeted of the residues Met113, Thr117, Asn139. The disclosure of this potential binding mode warrants further clinical evaluation of theaflavin-3,3′-digallate as an anti-hemolytic compound in order to practically validate our results.
A hajas sejtes leukémia és kezelése
Authors: Demeter Judit
Published: October 2023

A hajas sejtes leukémia (HSL) típusos klinikai, morfológiai, immunhisztokémiai és genetikai jellemzőkkel rendelkező splenikus B-sejtes lymphoma. Ezen indolens lymphomában szenvedő betegek többségének a várható élettartama ma a purinnukleozid analóg kezelés révén már megegyezik az egészséges populációval. Mivel azonban szinte minden betegen bekövetkezik a visszaesés, és ezek a betegek újabb gyógyszeres kezelésre szorulnak, különösen fontos az új, kemoterápia-mentes terápiás lehetőségek ismerete. A Covid–19 infekcióban vagy egyéb aktív fertőzésben szenvedő és tüneteket okozó, progresszív HSL-ben szenvedő betegek kezelésére a molekulárisan célzott, BRAF-gátló kezelések, ill. a pegilált alfa-interferon adnak lehetőséget.
A haemophagocytás lymphohistiocytosis jellemzőinek, diagnosztikájának és kezelési lehetőségeinek áttekintése egy T-sejtes lymphomás beteg bemutatása kapcsán
Authors: Számel Anna , Földeák Dóra Melinda , Modok Szabolcs , Krenács László , Bagdi Enikő , Borbényi Zita
Published: October 2023

Bevezetés

A haemophagocytosis egy agresszív, életet veszélyeztető, megfelelő kezelés ellenére is gyakran halálos kimenetelű kórkép, melyben az immunrendszer túlzott aktivációja a haemopoietikus sejtek pusztulásához vezet. A kórkép kiváltó tényezője lehet többek között bármilyen malignus betegség, infekció, valamint szerzett vagy örökölt immunhiányos állapot jelenléte. Általában akut lázas kórkép formájában jelentkezik, többszervi érintettséggel. A leggyakoribb klinikai tünetei a láz, hepatosplenomegalia, cytopenia, májfunkciós eltérések, alvadási zavarok, emelkedett triglicerid, ferritin és laktát-dehidrogenáz szint. A diagnosztikai kritériumok a fentiek mellett tartalmazzák a csontvelő biopsziát és különböző immunológiai teszteket is.

Eredmények

A diagnózis felállítását, illetve a kezelési lehetőségeket egy agresszív citotoxikus T-sejtes lymphoma miatt gondozott betegünk esetén keresztül mutatjuk be. Több vonalbeli kemoterápiás kezelést követően sürgősségi felvételére láz, májelégtelenség miatt került sor. Laborjában emelkedett májfunkciós értékeket, gyulladásos paramétereket, laktát-dehidrogenáz, triglicerid és ferritin szinteket, beszűkült vesefunkciót, valamint anemiát és thrombocytopeniát láttunk. Hasi ultrahang-vizsgálat során hepatosplenomegalia ábrázolódott. A csontvelővizsgálat eredménye pedig a klinikai adatok alapján sejthető haemophagocytosist alátámasztotta, valamint a lymphoma relapszusát mutatta. Elsőként intravénás szteroid- és nagy dózisú vénás immunglobulin-kezelést adtunk. Ezt követően a csontvelő-biopszia eredményének ismeretében a beteg kezelését etopoziddal egészítettük ki, mely mellett a klinikai tünetek és a laborparaméterek jelentős, de csak átmeneti javulását észleltük.

Következtetés

A haemophagocytosis egy életet veszélyeztető kórkép, ami a T-sejtes lymphomás betegek nehéz sorsát tovább ronthatja. A korai diagnózis és a kiváltó oknak megfelelő kezelés késleltetheti a többszervi elégtelenség kialakulását, ugyanakkor a prognózist a lymphoma lefolyása határozza meg.
Realny system rządów w Polsce po akcesji państwa do Unii Europejskiej
Authors:   Uniwersytet Warmińsko-Mazurski w Olsztynie, Tomaszewski Waldemar
Published: October 2023

The subject of research presented in the article is the system of government in Poland. The considerations concern the relationship between the normative solutions defined in the Constitution of the Republic of Poland of 1997 and the influence of the EU on the modification of political solutions in Poland. It was hypothesized that after Poland’s accession to the EU, the system of government in Poland changed in terms of political practice. It has been shown that functioning in the EU resulted in a departure from the characteristic rationalization of the system of government and bringing it closer to the parliamentary model. The prediction presents possible further directions of modification of the system of governance depending on the evolution of the EU. The research was based on the following methods: institutional-legal, systemic and comparative.
Modelling COVID-19 Fluctuation in Nigeria Using Fractional Integrated Garch Model
Authors: Wiri Leneenadogo , Sibeate Pius U.
Published: October 2023

This study applied a fractionally integrated GARCH (FIGARCH) process in modelling daily cases of COVID-19 in Nigeria from 28 February 2020 to 23 March 2022. The time plot of the series showed the constant fluctuation in the study variable. The daily COVID-19 data was tested for stationarity
using Augmented Dickey-Fuller (ADF), the series was not stationary. The Geweke and Porter-Hudak (GPH) method was used to estimate the long memory parameter d of the FIGARCH model. The daily series was stationary at a fractional differencing of order (d=0.97). The presence of long memory was
also detected using the autocorrelation function. The fractionally integrated GARCH model was used to detect the period of high and low crisis. The crisis period was identified by volatility clustering and the leverage effect process. However, four models were estimated for FIGARCH models.
The best model was selected based on the information criteria. Finally, the most adequate model for estimating the volatility of COVID-19 in Nigeria was the FIGARCH (1,0.97, 1) model.
TURNOVER STABILITY CAUSED BY GAPS IN A BADMINTON SHUTTLECOCK
Authors: Hasegawa Hiroaki , Nakagawa K.
Published: October 2023

The badminton shuttlecock is an airborne projectile with high turnover stability. The angle of attack
of a shuttlecock immediately changes after its initial contact with a racket. The flipping shuttlecock
quickly shifts to stable flight. The purpose of this study was to investigate the shuttlecock's turnover
stability by examining the unsteady flow fields during flip movements. Wind tunnel experiments were used to model the flipping motion, and the particle image velocimetry measurement was applied to visualize the unsteady flow field around the shuttlecock. In this study, a shuttlecock without gaps was also used to demonstrate the effect of the flow through the gap on the turnover stability. The turnover stability of the standard shuttlecock (with gaps) was better than that of the shuttlecock without gaps. The flow through the gaps in the standard shuttlecock produced a vortex behind it, which increased the pressure difference between the shuttlecock's front and back sides and enhanced the restoring force. This restoring force actively contributed to the turnover stability of the shuttlecock.
When is Aquatic Resource Type Conversion Appropriate: A Framework for Cleaning Sand out of the Gears and a Case Study for McInnis Marsh
Authors:   US EPA, Region 9, San Francisco, CA, Siul Jennifer , Stein Eric ,   Southern California Coastal  Water Research Project, Costa Mesa, CA, Brown Jeff ,   Southern California Coastal  Water Research Project, Costa Mesa, CA
Published: October 2023

Wetland and stream restoration projects may sometimes involve converting one “type” of aquatic habitat to another “type” (e.g., managed salt ponds into tidal marshes, depressional wetlands into streams, marsh into transition zone habitat). This “type conversion” may be necessary and beneficial in the context of addressing watershed plans or regional restoration goals, or in achieving resiliency to climatic changes (Goals Project 2015). Conversion can also occur through other large-scale, complex actions (e.g., mitigation banking initiatives). Whether driven by habitat restoration goals or compensatory mitigation needs or both, regulatory oversight typically governs the process. Holistically assessing such conversion through the regulatory lens is challenging for permitting programs. To address this challenge, an interagency team of federal and state regulators and resource managers in California developed a structured and transparent approach for evaluating the appropriateness of aquatic resource type conversion. The resulting framework can support project planning and inform regulatory evaluation by helping to answer: 1) what loss or gain of function is expected from various aquatic resource type conversions, and 2) whether conversion might be ecologically (or functionally) appropriate. The intent is to support agencies’ technical and regulatory decisions by providing a standardized, transparent set of tools and approaches that can inform discussions between agencies and with project proponents during the project evaluation phase, with a goal of ensuring that projects are not only permittable, but environmentally beneficial.