bluuebunny/crossref_metadata_2025 huggingface dataset:
Identifying Novel Targetable Chromosomal Alterations in Ovarian Cancer: Using Germline Copy Number Variation Association Analysis
Authors: Abd Elmoneim Hanan , Mohammed Rehab , Abd El-Meguid Reda , Tawfik Heba , Abd Elghany Manal , Albar Halah , Basalamah Mohammed , Toni Nisreen
Published: September 2022

The heterogeneity of ovarian cancer (Ov Ca) is attributed to multiple genetic and epigenetic changes, rendering it difficult to detect the most relevant molecular alterations. Identifying copy number variations (CNVs) will be helpful in screening patients with a familial history and will ultimately facilitate early diagnosis. This work aims to determine germline CNVs that may be associated with risks for different subtypes of ovarian cancer. Using Affymetrix genome-wide human SNP 6.0 arrays, 138 germline DNA samples of non-familial ovarian cancer were analysed using Golden Helix (SVS7) software. CNVs overlapping the EYA2 (20q13.12) and WNK1 (12p13.33) genes are the top hits with a significant p-value (<0.05). Deletion is more frequent in normal and low-grade carcinomas. Commonly, ovarian cancer is copy neutral (CN2) or has copy number gains (CN3). Amplification at these locations is associated with high-grade cases, which have worse overall survival rates. A CN3 in the WNK1 gene is associated with a higher expression of mRNA. It could be concluded that ovarian cancer is associated with CN3s where the segments of DNA overlap WNK1 and EYA2. The oncogenic effect of WNK1 and EYA2 on ovaries may serve as prognostic markers for ovarian cancer.
IRON PRODUCTION IN THE NKAR ETHNIC GROUP OF THE GRASSFIELDS OF CAMEROON: THE PLACE OF TRADITIONAL MEDICAL PRACTICES
Authors: DZEAWONI ATLEE , TANTO TALLA RICHARD , NGU CHEO VICTOR
Published: September 2022

In the production chain of the African iron working industry, symbolism was present all through these processes. The environmental and cultural context in which these operations took place, were reflected in the type of furnaces, and techniques used in each iron working agglomerate. Symbolism in this study is linked to traditional medical practice, which was identified in the iron working agglomerates in the Nkar polity. Nkar is found in the higher plateau of the Grassfields of Cameroon. This paper made use of primary and secondary sources; together with archaeological techniques as methodology. The study revealed that, in the Nkar ethnic group, traditional medical and pharmaceutical practices were absorbed by iron workers on part time basis. This probed up because, accidents occurred in iron, kaolin and flux mines, and in the dangerous activity of smelting and smiting. These incidents needed first aid treatment. The ability of iron workers to effectively handle these ailments; linked them to traditional medical practitioners as a societal phenomenon. This paper concludes that, the ability of iron workers to handle medical conditions demonstrates an element of symbolism in the African metallurgy, and that, smelters could experiment and implement pharmaceutical/medical procedure. They however, remained mystical in approach.
EFFECT OF PACKAGING ON CONSUMER BUYING BEHAVIOUR IN COSMETIC INDUSTRY (A STUDY OF SELECTED CONSUMERS IN ANAMBRA STATE)
Authors: NGWUBE ANGEL CHINENYE , O. NANA GOODLUCK , IKENNA MADUMERE HUMPHREY
Published: September 2022

This paper seeks to bring an overview of the effect of packaging on consumer buying behaviour in the cosmetics industry. The study focused on packaging elements (colour, design wrapper, package material, printed information and innovation), and how they affect consumer buying behaviour. A structured questionnaire was developed to measure the variables used for the study. A survey research design was adopted and the Topman formula was used to determine the sample size of 246. Copies of questionnaires were distributed to the respondents and 240 were retrieved. Pearson correlation and linear regression were used to test the hypotheses, the findings revealed that colour, package material, design wrapper, printed, information and innovation have a significant effect on customer buying behaviour. Based on the results, the study recommended among others that manufacturers of cosmetics should give attention to good packaging elements; the container should be of good value to avoid product damage.
DETERMINATION OF THE FUNCTIONAL FIRE HAZARD CLASS OF THE OBJECT OF PROTECTION
Authors: Лагозин Андрей Юрьевич , Земский Геннадий Тимофеевич , Ильичев Александр Валерьевич , Кондратюк Наталья Валентиновна
Published: September 2022

В настоящее время определение класса функциональной пожарной опасности объектов защиты осуществляется по усмотрению пользователей интуитивно без возможности экспертной проверки, из-за отсутствия правила отнесения зданий, сооружений и пожарных отсеков к классам функциональной пожарной опасности (ФПО). Между тем от правильного определения класса ФПО зависит выбор средств и способов противопожарной защиты. Целью данной публикации является расширение перечня объектов, относящихся к каждому классу ФПО, с использованием данных классификатора объектов капитального строительства, а также разработка предложений по усовершенствованию классификации ФПО.

At the present time the determination of the functional fire hazard class of the objects of protection is carried out at the discretion of users intuitively without the possibility of expert verification, due to the absence of a rule for assigning buildings, structures and fire compartments to functional fire hazard classes. The selection of means and methods of fire protection depends on the correct definition of the functional fire hazard class. The purpose of the paper is to expand the list of objects belonging to each functional fire hazard class using data from the classifier of capital construction objects, as well as to develop proposals for improving the classification of functional fire hazard.
Institutional Restructuring and Reforms for National Development
Authors: Baridam Don M. , Don-Baridam Letam Q. , Usoro Malachi
Published: September 2022

This paper argues that weak national institutions cannot be relied upon to produce successful restructuring and reform packages that can lead to accelerated national development and higher living standards for the Nigerian people. The paper further identifies weak national institutions, the pursuit of pecuniary individual and group interests, ethnic cleavages and intra-ethnic rivalries among the elite class, including the extractive nature of politics and economic pursuits, as major factors militating against successful restructuring and meaningful institutional reforms in Nigeria, which are hinged on accelerated technological innovation, political development and wealth creation. The paper concludes that only strong and functional institutions, inclusive political and economic policies, and innovative leadership can bring about accelerated national development in Nigeria.
A Review On Self-Confidence and How to Improve It
Authors: Messaoud Houssem Eddine Ben
Published: September 2022

Self confidence is one of the most important traits a person can possess, and it is something we all strive to achieve. In fact, if you ask anyone who has achieved great success in their life what they think are the key ingredients to being successful, they will tell you “Self-confidence”. There are many different types of self confidence but here I am going to focus on the kind that comes from within yourself as opposed to the kind that comes from outside sources like others’ opinions or even your own past experiences.
Assessing the Relationship Between Hiring Practice and Quality Service Delivery in Counties of the Lake Region Economic Bloc Kenya
Authors: Olala Gordon Odongo , Kimutai Geoffrey , Ngacho Christopher
Published: September 2022

Human Resource management practices like hiring is some of the practices which made County governments in Kenya to be inaugurated in the year 2013 to help deliver quality services. Since then, it has been evident that County governments have been experiencing a myriad of problems that constrain their delivery capabilities. This study aimed at assessing the relationship between hiring practice and quality service Delivery in Lake Region economic bloc county governments in Kenya. This study was anchored on objective factor theory supported by expectancy and human capital theories. The study used an explanatory design. The target population was nine hundred and eighty-five counties resource officials. A sample size of 356 through Yamane‟s (1979) sample size formula at a 95% confidence level, p=0.5 formula was used. Stratified and simple random sampling was applied. Data collection was through questionnaire. Results for the objective, hiring practice was positively significant in relationship to quality service delivery. The study recommended that, County government should always engage professional associations in hiring process and ensure appropriate hiring methods.
The abundance and distribution patterns of sea urchins in Botubarani waters, Tomini Bay, Indonesia
Authors: Kadir Wiyanti Abd , Hamzah Sri Nuryatin , Nane La
Published: September 2022

This study aims to determine the abundance and distribution patterns of sea urchins in Botubarani Waters, Kabila Bone District, Bone Bolango Regency. This research was conducted from July to August 2020. A total of three research stations were established, namely West Tamboa, Central Tamboa and East Tamboa. The abundance of sea urchins was calculated using a quadrant transect measuring 1 × 1 m, which was laid 25 m perpendicular to the coastline using a line transect. Sea urchin species found were identified in situ and the distribution pattern of sea urchins was calculated using the morista dispersion index. The results showed that there were 5 types of sea urchins in Botubarani Beach, namely Echinometra mathaei, Diadema setosum, Echinotrix calamaris, Echinotrix diadema and Tripneustes gratilla. The sea urchin type Echinometra mathaei is the species with the highest abundance in all research stations, namely 25 ind./m2 at Tamboa Barat station, 9 ind./m2 at Tamboa Tengah station and 7 ind./m2 at Tamboa Timur station. The distribution patterns of sea urchins found in Botubarani waters include clusters for Echinometra mathaei and uniform patterns for sea urchins Diadema setosum, Echinotrix calamaris, Echinotrix diadema and Tripneustes gratilla. ANOVA analysis results show that there is no significant difference between sea urchin abundance and water quality parameters in all research stations. This indicates that there is no difference in environmental conditions at the three sampling locations.
Development strategy for marine ecotourism area in Pohuwato District (a case study at Pohon Cinta Beach and Tanjung Maleo Beach)
Authors: Arman Veggy , Olii Abdul Hafidz , Hasim Hasim
Published: September 2022

This research aims to know the marine ecotourism suitability, carry capacity of the area, and to formulate a strategy for managing ecotourism areas in Pohuwato District. This research is conducted at the Pohon Cinta beach and Tanjung Maleo beach. The data analysis is done by measuring the land suitability index, area carrying capacity, and SWOT Analysis. The result of the suitability analysis of beach tourism shows that the Pohon Cinta beach tourism area is suitable for beach recreational activities, boating, banana boating, and jet skiing as well as is suitable for swimming. Tanjung Maleo beach area is suitable for all activities, such as beach recreational activities, swimming, boating, banana boating, and jet skiing. Pohon Cinta beach tourism area can accommodate around 9.840 people/day, and Tanjung Maleo can accommodate around 2.640 people/day. Strategy for managing the tourism area of Pohuwato District, including promoting tourist attraction, formulating policies, determining coastal areas that need protection, coordinating each related party, inviting the community and visitor to take part in preserving the environment, improving the quality of torism area, improving coordination between the district government and the community, socialization of coaching and educational campaigns, increasing natural disaster mitigation efforts, the government monitoring, adding tourist facilities, and developing non-govermental activities.
Kwandang waterfront city development study against the water conditions of north gorontalo regency
Authors: Djau Bambang
Published: September 2022

Kwandang Waterfront City is a directive on urban development plans by Government Regency of North Gorontalo where there is a plan for coastal reclamation with beachfront conditions are dense settlements. However, it has not been stated in the Zoning Plan of Coastal Areas and Small Islands (RZWP3K) in Gorontalo Province. This paper aims to explore the feasibility of Kwandang Waterfront City development to changes in the physical condition of the aquatic environment of the North Gorontalo Regency through spatial analysis and weighting methods. The results of this paper can be taken into consideration in conducting a review of Coastal Spasial Plan, as a form of support for the Kwandang Waterfront City urban development plan.
Prediction of Erotion Rate in Two Elbows for Coal-Air Flow Based on Computational Fluid Dynamics Simulation
Authors: Bayu Triwibowo  , Heni Wahyu Widayanti  , Miftakhul Indra Rukmanasari
Published: September 2022

Corrosion is one of the problems cause the material fail, leaks in the equipment and pipe systems in the industry which caused distrub in productivity of production in industry. There are some ways to prediction erosion in pipes, with the conventional or manual and CFD. CFD is to prediction erosion in turbulent air flows with variations in coal particle size and velocity of flowing air. The results of prediction erotion based on CFD is numerical and graphic, by displayed numerical results into visual results. These results include about the velocity, pressure, and temperature distribution in the air flow. So, CFD can be used to prediction pipe because it has wide coverage and effective in display numerical and visual results. Discreate Phase Model is the model of CFD with a variable stream velocity of 10 m/s, 15 m/s, 20 m/s and a solid loading of 5%, 10%, 15%, 20%, 25%. From the results, the maximum erosion rates increased with increasing sizes of particles and stream velocities. However, the location of the maximum erosion rate in the elbows region was independent on those mentioned parameters.
The bees of the genus Andrena Fabricius, 1775 (Hymenoptera, Andrenidae) described by Ferdinand Morawitz from the collection of Aleksey Fedtschenko
Authors: Astafurova Yulia V. , Proshchalykin Maxim Yu. , Sidorov Dmitry A.
Published: September 2022

The type specimens of the genus Andrena Fabricius, 1775, described by Ferdinand Morawitz from the collection of Aleksey Fedtschenko deposited in the Zoological Museum of the Moscow State University and in the Zoological Institute, Russian Academy of Sciences, St. Petersburg (Russia), are critically reviewed. Precise information with illustrations of types for 52 taxa is provided; of these 39 species are valid and thirteen are invalid (ten synonyms and three homonyms). Lectotypes are here designated for the following 24 nominal taxa: Andrena acutilabris Morawitz, 1876, A. aulica Morawitz, 1876, A. bicarinata Morawitz, 1876, A. combusta Morawitz, 1876, A. comparata Morawitz, 1876, A. corallina Morawitz, 1876, A. discophora Morawitz, 1876, A. fedtschenkoi Morawitz, 1876, A. initialis Morawitz, 1876, A. laeviventris Morawitz, 1876, A. leucorhina Morawitz, 1876, A. mucorea Morawitz, 1876, A. nitidicollis Morawitz, 1876, A. oralis Morawitz, 1876, A. planirostris Morawitz, 1876, A. ravicollis Morawitz, 1876, A. rufilabris Morawitz, 1876, A. sarta Morawitz, 1876, A. smaragdina Morawitz, 1876, A. sogdiana Morawitz, 1876, A. subaenescens Morawitz, 1876, A. tuberculiventris Morawitz, 1876, A. turkestanica Morawitz, 1876, and A. virescens Morawitz, 1876.
Travail relationnel et travail de sens dans l’activité de professionnel·les de l’accompagnement. Reconnaissance et dilemmes au cœur du métier
Authors: Cardoso Stéphanie , Muller Mirza Nathalie
Published: September 2022

L’évolution des réglementations suisses pour l’intégration de réfugié·es affecte les activités d’accompagnement. Le cœur du métier est défini par la relation avec les bénéficiaires, mais celle-ci place les professionnel·les dans des enjeux de divers ordres. Cet article vise à examiner la manière dont les professionnel·les de l’accompagnement donnent sens à leur activité dans un contexte instable. Nos résultats montrent que des dilemmes sont perçus par les professionnel·les, qui mettent en lumière des enjeux de reconnaissance.
Regularity criteria for a two dimensional Erying-Powell fluid flowing in a MHD porous medium
Authors: Palencia José Luis Díaz , Rahman Saeed Ur , Hanif Saman
Published: September 2022

The intention and novelty in the presented study were to develop the regularity analysis for a parabolic equation describing a type of Eyring-Powell fluid flow in two dimensions. We proved that, under certain general conditions involving the space of bounded mean oscillation ($ BMO $) and the Lebesgue space $ L^2 $, there exist bounded and regular velocity solutions under the $ L^{2} $ space scope. This conclusion was additionally supplemented by the condition of a finite square integrable initial data (also some of the obtained expressions involved the gradient and the laplacian of the initial velocity distribution). To make our results further general, the proposed analysis was extended to cover regularity results in $ L^{p}\left(p > 2\right) $ spaces. As a remarkable conclusion, we highlight that the solutions to the two dimensional Eyring-Powell fluid flow did not exhibit blow up behaviour.
Utilisation of phosphogypsum along with other additives in geo- engineering- A review
Authors: Anamika B. , Debabrata G.
Published: September 2022

Various adverse effects and hydro-mechanical failures of soil are the dominant effects of global warming. At the same time, rapid industrial development has produced several by-products on a large scale. The reuse of industrial residues in different engineering fields without compromising the technical characteristics is propitious from the engineering, environmental, ecological and economic points of view. Phosphogypsum (PG) can be used as an alternative civil engineering material as it is rich in calcium sulphate, although it contains some radioactive molecules. Researchers are continuing to investigate the utilisation of PG by mixing it with other traditional materials to convert into alternative materials when the radioactive minerals are within the permissible limits. However, the contamination effect can be reduced by treating with citric acid. This review paper presents details of the increase in strength parameters and permeability of PG when combined with other wastes materials used in different geotechnical fields.
Psychological Consequences and Coping Strategies of Health-Care Workers in COVID Section of a Tertiary Hospital: A Qualitative Study
Authors: Thaper Kashish , Datar Manjiri , Shetty Jyoti , Bhattacharya Anshumi
Published: September 2022

Background:

Health-care workers (HCWs) working in COVID care are vulnerable to various psychological stressors. The novel nature of infection and exponential increase in cases add to the workload and psychological distress. Hence, assessing the psychological consequences and methods of coping in these HCWs is important. The detection can help in devising appropriate psychological interventions for them.

Aim:

The aim of this study was to assess the psychological reactions, symptoms, and coping strategies of HCWs in COVID section of a tertiary hospital.

Objectives:

The objectives of this study were as follows: (1) to explore various psychological reactions, stressors, psychological symptoms, and coping skills of doctors, nurses, and support staff working in COVID section of a tertiary care hospital and (2) to correlate the psychological reactions, stressors, and psychological symptoms with sociodemographic factors.

Methodology:

This was a qualitative study. A total of 100 HCWs including doctors, nurses, and support staff working in COVID section of hospital were interviewed for psychological consequences and their coping strategies. Their narratives were coded into themes and analyzed.

Statistical Analysis:

Frequency and percentages for quantitative variables were used for statistical analysis. Chi-square test was used for correlation of qualitative variables.

Results:

The HCWs reported various psychological reactions of worries about their own health which was significant in HCWs in intensive care unit (χ
2 = 12.35, P = 0.002) and had concern of nature of work, which was a significant concern in doctors (χ
2
= 9.59, P = 0.008). The stressor of uncomfortable personal protective equipment was found to be reported more significantly by support staff (chi2 = 11.1, P = 0.03), and that of long and burdensome work reported more significantly by females (chi2 = 4.64, P = 0.03). They had prominent psychological symptoms of irritability significantly reported by doctors (χ
2
= 9.91, P = 0.007), sleep disturbances significantly reported by unmarried (χ
2
= 6.76, P = 0.009), and by nurses (χ
2
= 9.7, P = 0.008). The most common coping strategies used were acceptance, problem-solving strategies, and communicating with family members and colleagues.

Conclusion:

The HCWs in COVID section had stressors with psychological reactions and symptoms and used various coping strategies to deal with them.
Role of inhaled levosimendan in peripartum cardiomyopathy
Authors: Kaur Parminder , Kundra Tanveer S.
Published: September 2022

Levosimendan is an inodilator agent, which was initially widely used in low contractility states. However, its use has been restricted because of the invariable need to use a vasoconstrictor like norepinephrine, since it causes a marked fall in systemic vascular resistance (SVR). Hence its beneficial effects on the heart are compromised by the excessive fall in SVR. The inhalational route provides a better opportunity to exploit the positive cardiac effects, with a minimal effect on SVR. In this case report, we present a postpartum patient presenting with heart failure, in which inhalational levosimendan improved the hemodynamics and cardiac function, which was associated with relief of symptoms, with no need for other inotropes. As per our knowledge and extensive literature search, this is the first documented use of inhaled levosimendan in peripartum cardiomyopathy.
Evaluation of risk factors for unanticipated hospital admission following ambulatory surgery – An observational study
Authors: Alharthi Ahmed A. , Mohammed Alshaqha , Jamil Mohammad , Mehboob Amjad , Huda Anwar U.
Published: September 2022

Context:

Unanticipated admissions following ambulatory surgery significantly affect hospital admission and operation room flow. Most of the factors responsible for unanticipated admission following ambulatory surgery were preventable. It is, therefore, crucial to improve patient selection criteria and to identify the risk factors for unanticipated admission during preoperative period. These unanticipated admissions have now been considered as quality care indicator and a target to improve healthcare costs.

Aims:

To assess the reasons and risk factors for unanticipated hospital admission after ambulatory surgery.

Settings and Design:

Security Forces Hospital, Riyadh, Kingdom of Saudi Arabia.

Methods and Materials:

In this case-control study, cases who were re-admitted within 48 hours following ambulatory surgery were included. The convenience sampling was used to identify controls. Data including patients' demographics, type of anesthesia and surgery, any intraoperative or postoperative complications, etc., were extracted.

Statistical Analysis Used:

Descriptive statistics is used to summarize the study variables. Mean and standard deviation were used for quantitative variables. Percentage and frequencies were used for qualitative variables. Univariate and multivariate logistic regressions were used to assess risk factors for unanticipated hospital admission after ambulatory surgery.

Results:

There were 153 cases and 147 controls in this study. The study found postoperative pain as the most common reason for re-admission after ambulatory surgery followed by bleeding, fever, and asthma exacerbation. Multivariate logistic regression showed age, BMI more than 40, and presence of respiratory disease as risk factors (P < 0.05).

Conclusions:

Age, high BMI more than 40, and presence of respiratory disease increase the risk of unanticipated hospital admission after ambulatory surgery.
Write a Scientific Paper course – Utility or otherwise?
Authors: Grech Victor , Cuschieri Sarah , Eldawlatly Abdelazeem A.
Published: September 2022

Background:

Publish or perish is a cliched mantra but publishing requires the acquisition of a wide set of disparate skills that are typically learned in a completely ad-hoc manner in an early period of one's career. The Write a Scientific Paper (WASP) course is delivered online by an experienced, international faculty of academics, including several medical journal editors. This study retrospectively analyzed the attendees' perceptions of the usefulness and the utility of WASP.

Methods:

An email questionnaire of 11 questions was sent to all previous WASP attendees, 370 subjects, in May 2022. The questions included the geographical locations of the subjects as well as the number of published articles before and since WASP course. Besides a couple of questions on rating and recommending the WASP course, some other related questions were also asked.

Results:

There were 68 responses (18%) with high agreement (Cronbach α = 0.92). The WASP course fared well across the different research-oriented dimensions and expectations and is mostly welcomed by young career professionals. Following WASP, a 9% increase in scientific writing and published articles engagement was reported.

Discussion:

WASP is an international and unique course that emphasises presentation skills using newspaper media theory. It highlights to the delegates the importance of understanding the conflicting tripod of forces that govern publishing. Authors wish to publish more; readers are inundated, wishing to read less, whereas journal editors' primary aims are to elevate their journals' impact factors. WASP endorsements and the testimonials are invariably positive. The transition to online barely affected satisfaction rates with WASP while permitting the enrolment of a more international faculty that includes even more journal editors. WASP's ultimate objective is to impart the faculty's collective experience to the delegates in this crucial, early aspect of career progress.
Validation of translated Obstetric Quality of Recovery (ObsQoR-10A) score after nonelective cesarean delivery (CD) in an Arabic-speaking population
Authors: Mukarram Shumaila , Ali Shoukat , Zulqurnain Muhammad , Alkadi Ibtihal A. M. , Alhatlan Abdulelah I. , Abbasi Mohammed Z. H. , Mushtaq Muhammad Q. , AbuHammad Ahmed Y. , Shahid Khalida , Waqas Asghar , Shafqat Atif
Published: September 2022

Background:

The ObsQoR-11 is a validated scale that assesses recovery after cesarean delivery (CD). This observational study aimed to evaluate the psychometric properties of its Arabic version.

Methods:

The original ObsQoR-11 was translated into an Arabic version (ObsQoR-10A). All participants completed the ObsQoR-10A at 24 h and 48 h postoperatively after CD. Validity, reliability, responsiveness, and feasibility were assessed.

Results:

The ObsQoR-10A correlated with Global Health Numerical Rating Scale (NRS) at 24 h (R = 0.68, 95% CI: 0.56–0.80, P < 0.001) and at 48 h (R = 0.66, 95% CI: 0.54–0.78, P < 0.001) and differentiated between good and poor recovery (median scores at 24 h 88 vs. 71, P < 0.001; at 48 h 95.5 vs. 70, P < 0.001). ObsQoR-10A correlated with hospital length of stay at 24 h (R = −0.21, 95% CI: −0.40 to −0.02, P = 0.03) and at 48 h (R = −0.21, 95% CI: −0.40 to −0.03, P = 0.02); gestational age at 24 h (R = 0.22, 95% CI: 0.03–0.40, P = 0.02); change in hemoglobin at 24 h (R = −0.30, 95% CI: 0.51 to −0.10, P < 0.01); and total opioids at 48 h (R = −0.45, 95% CI: −0.62 to −0.27, P < 0.001). There was a significant difference between 24 h and 48 h postoperative ObsQoR-10A scores (median difference: −18; P < 0.001 which shows responsiveness). Other key measures included a Cronbach's alpha of 0.87, split-half 0.75, and intra-class correlation >0.62 with no floor or ceiling effects. Median (IQR) completion time was 3 (3-5) and 3 (2.5-3.5) minutes at 24 h and 48 h.

Conclusions:

ObsQoR-10A is a valid, reliable, responsive, and a clinically feasible tool in an Arabic-speaking obstetric population.
Pulmonary artery catheter knot in a liver transplantation, a rare complication
Authors: Silva Felipe L. , Gomes José L. U. M. , Boas Walkiria W. V. , de Freitas Gabriela V.
Published: September 2022

The pulmonary artery catheter (PAC) measures hemodynamic parameters in real time, providing valuable data for the management of the critical patient. Nevertheless, its use is associated with several complications. Knot formation is a rare complication related to PAC insertion. A 51-year-old patient with complicated ethanolic liver cirrhosis underwent orthotopic liver transplantation. Invasive hemodynamic monitoring was performed using a Swan–Ganz pulmonary artery catheter (PAC) inserted through the right internal jugular vein. Chest X-ray in the immediate postoperative period showed the presence of a possible knot adjacent to the tip of the sheath in the internal jugular vein. The patient was then referred to the hemodynamics room, where, through fluoroscopy, a true knot was successfully removed after femoral vein dissection. The medical team should weigh the risk and benefit of using the PAC, taking into account the patient's clinical conditions, the benefits, and possible complications of the procedure.
Engineering of the Highest Caliber: Kazimierz Siemienowicz and the Culmination of the Military Revolution
Authors: Wlodkowski Paul
Published: September 2022

The interregnum between the death of Galileo and the publication of Newton’s Principia produced great advances in military science and technology. Particularly noteworthy are Kazimierz Siemienowicz’s contributions to artillery and to the field of rocketry. The dominating nature of these weapon systems remain as relevant today as it did in 1650 with the publication of his opus, The Great Art of Artillery. Rocket technology defines power relations, whether fired indiscriminately across a national border or positioned menacingly in a silo as an intercontinental ballistic missile. Siemienowicz’s designs, namely his multi-stage rockets with delta-wing stabilizers and ejection nozzles, became instruments of state power. The standardization of the caliber scale, the writing of the science of artillery, the optimization of gunpowder quality, and the pioneering work in rocketry, which became his legacy, qualify him as principal in the culmination of the military revolution.
Kontakty AU/PAU z instytucjami kanadyjskimi w latach 1872–1952 w świetle Roczników Akademii
Authors: Petelska Michalina
Published: September 2022

Dotychczas w literaturze naukowej stosunków polsko-kanadyjskich nie rozpatrywano w kontekście historii nauki. Niniejszy artykuł stanowi rekonesans badawczy. Zagadnienie zostało zbadane na podstawie „Roczników Polskiej Akademii Umiejętności” – jednej z najważniejszych polskich instytucji naukowych. Analiza materiału źródłowego wykazała, że pierwsze kontakty nawiązano już w latach osiemdziesiątych XIX wieku. W kolejnych latach Akademia rozwijała wymianę publikacji naukowych z kanadyjskimi uniwersytetami, muzeami i towarzystwami naukowymi.
Juda Kreisler (1904–1940s?): A Bio-Bibliographical Sketch of a Lviv Physicist and a Popularizer of Science
Authors: Rovenchak Andrij , Rovenchak Olha
Published: September 2022

We present a detailed biographical account and analysis of works of Juda Kreisler (1904–1940s?), a theoretical physicist from Lviv. He was born in Tlumach (Ukrainian: Тлумач, Polish: Tłumacz, Yiddish: טאלמיטש ), nowadays a town in Ivano-Frankivsk oblast in the western part of Ukraine. In 1923, Juda Kreisler finished a gymnasium in Stanislaviv and entered the Philosophical Faculty of the University of Lviv (Wydział Filozoficzny Uniwersytetu Jana Kazimierza [UJK] we Lwowie) in order to study physics. In 1932, he was promoted to the doctoral degree in physics under the supervision of Professor Stanisław Loria. For a short period in the 1930s, Juda Kreisler worked at the Department for Theoretical Physics of the University of Lviv, and returned to the University in 1940, after the Soviets had reorganized it upon taking over Lviv in September 1939. His fate remains unknown: he is listed among murdered by Nazis Jewish employees of the University of Lviv in 1941–43.

Dr. Kreisler authored four scientific papers and four abstracts of conference presentations delivered at the Congresses of Polish Physicists in 1932–36. There is, however, another field, where he was extremely prolific in the late 1930s. We have discovered 122 of his popular articles in “Chwila” (English: “Moment”), a local daily newspaper published by the Jewish community in Lviv during 1919–39. These articles covered various subjects, that can be tentatively divided into the following major topics: chronicles and personalia; history of science; discoveries, new studies and inventions; the applied value of science (for medicine and economy in particular); interconnection between science and war; organization of scientific life; Hitler’s Germany and the problem of so-called ‘Aryan science’. While various branches of physics formed the largest part within disciplines reflected in Juda Kreisler’s articles, he also discussed biology, chemistry, meteorology, and geology. The latter field is closely related to his professional career at Lviv’s Geophysical Institute of “Pionier”, a joint-stock company for the exploration and exploitation of bituminous materials, where he spent nine months in 1936.
Abram Slutskin and Radiophysics in Ukraine of the First Half of the 20th Century: World Dimension
Authors: Tverytnykova Elena , Gutnyk Maryna
Published: September 2022

The article discusses the scientific and pedagogical activity of the outstanding Ukrainian radiophysicist Abram Slutskin in the context of the development of world radiophysical research. It is substantiated that the theoretical works of the scientist defined a new direction of research in Ukraine, namely the radar, and were important for the development of ultrahigh frequency physics. Innovative research initiated by Abram Slutskin found application in new defense technologies, military equipment, and special devices for medicine, biology, navigation, communications, household television and the radio industry. The article proves that Abram Slutskin had priority in launching research in the field of biophysics in Ukraine. The research on the use of ultrahigh frequencies for treatment of oncological patients carried out by scientists were unique for that time. Abram Slutskin᾽s graduate students became well-known specialists, who further developed the scientist’s ideas by initiating innovative areas of research and creating new institutions. We have grounds to consider Abram Slutskin as one of the founders of the Ukrainian scientific radio-physical school.
Wykaz czasopism historycznych oparty na nowym modelu ewaluacji czasopism
Authors: Kozłowska Dorota
Published: September 2022

W artykule przedstawiono wyniki badań nad osiągnięciami techniczno-bibliometrycznymi czasopism polskich z dziedziny historia i archiwistyka, dyscyplina historia i porównano je z punktacją Wykazu czasopism naukowych i recenzowanych materiałów z konferencji międzynarodowych MEiN z dnia 21 grudnia 2021 r.
Celem takich badań jest dokonanie zintegrowanej, transparentnej oceny techniczno-bibliometrycznej czasopism historycznych i stworzenie nowego Wykazu czasopism historycznych przygotowanego przez Pracownię Naukoznawstwa IHN PAN.
Wszystkie zasady tego Wykazu będą wyraźnie określone i umożliwią redakcjom / instytucjom naukowym samodzielne wyznaczanie punktacji, a także pozwolą na poprawę działalności redaktorskiej i recenzyjnej oraz stworzenie przejrzystej strony internetowej czasopisma zawierającej wszelkie niezbędne dane dla ewentualnego autora i czytelnika.
Punktacja czasopism z historii nauki w Wykazach czasopism MNiSW (25.01.2017), MEiN (21.12.2021) oraz PN IHN PAN (2022)
Authors: Kokowski Michał
Published: September 2022

W artykule opisano typy czasopism z historii nauki, kryterium wyboru czasopism z historii nauki, transparentne kryteria ewaluacyjne czasopism naukowych przyjęte w „Wykazie czasopism Pracowni Naukoznawstwa IHN PAN” (2022) oraz podano punktację czasopism z historii nauki w Wykazach czasopism MNiSW (25.01.2017), MEiN (21.12.2021) oraz Pracowni Naukoznawstwa IHN PAN (2022).
Relationships between cytokines and the amounts of microsymbionts in microecological disorders of the human intestine
Authors: Bondarenko Taisiay A. , Ivanova Elena V. , Bekpergenova Anastasia V. , Chaynikova Irina N. , Chelpachenko Olga E. , Nikiforov Igor A. , Zdvizhkova Irina A.
Published: September 2022

Cytokines and chemokines, as well as gut microsymbionts, are sufficient participants in the intercellular communications, thus supporting homeostasis of gut mucosa. However, these components may be of key significance for intestinal inflammation and damage to epithelial barrier. This work expands the understanding of the relationships between intestinal microbial communities and the local cytokine network of the host. The paper presents the results of the correlation analysis between total microbial number of intestinal microsymbionts and the level of pro- (TNF, IFN, IL-8) and anti-inflammatory cytokines (IL-10, IL- 1ra) in coprofiltrates obtained from clinically healthy people examined for gut dysbiosis. Determination of cytokines in coprofiltrates was carried out by ELISA technique (JSC Vector-Best, Russia). The study of 65 microsymbiocenoses of the human gut was carried out by classical bacteriological methods. Identification of obligate-anaerobic, facultative-anaerobic bacteria and fungi was carried out by time-of-flight mass spectrometry using MALDI TOF-MS Microflex LT series (Bruker Daltonians, Germany). These studies have revealed the leading role of associations between enterobacteria, fungi and representatives of the Staphylococcus genus in gut dysbiosis. In general composition of the obligate-anaerobic association, we have observed a change of consortia from several types of Bifidobacteria and Lactobacilli in eubiotic state to a monoid variant in dysbiosis. At the same time, the number of associations that included Clostridia was increased. The analysis of correlations between cytokine indices and the number of gut microbiota showed persistance of significant associations established during eubiosis under dysbiosis conditions, with an increase in their correlation coefficient: Bifidobacterium spp., Enterobacteriaceae, Staphylococcus spp., Candida spp. and TNF. At the same time, in dysbiosis, the direction of the connections changed, and new correlations were determined: for Staphylococcus spp. and IFN; Staphylococcus spp. and IL-8; Enterobacteriaceae and IL-1ra, IFN. The established features of correlations between indices of microsymbiocenosis and quantitative changes in cytokines allow us to consider the number, composition of microsymbiocenosis and cytokine profile as factors that may affect the state of gut homeostasis in eu- and dysbiosis.
Human endogenous retrovirus HERV-E λ 4-1 in immunopathogenesis of affective disorder
Authors: Goldina Irina A. , Goldin Boris G. , Markova Evgeniya V.
Published: September 2022

The aim of this work was to study a dependence between the production level of some pro-inflammatory cytokines by peripheral blood mononuclear cells, and activation of human endogenous retrovirus HERV-E 4-1 in the patients with recurrent depression. Patients and methods: the study included 30 patients with an verified diagnosis of recurrent depression (F 33.0) aged 26-45 years, with a disease duration of at least 3 months prior to inclusion into the study. Peripheral blood mononuclear cells were isolated by centrifugation in Ficoll density gradient (1.078 g/cm3). The human endogenous retrovirus HERV-E 4-1 env gene expression was determined by polymerase chain reaction using paired oligonucleotide primers. To assess the cytokine production, peripheral blood mononuclear cells were cultured for 24-72 hours, depending on the experimental conditions. Quantitative determination of spontaneous cytokine production was carried out by a sandwich variant of ELISA method in conditioned media from the cell cultures, according to the manufacturer instructions. Results: our data reveal higher production of IL-1 and IFN in peripheral blood mononuclear cells from those patients with recurrent depression who showed detectable HERV-E 4-1 env expression compared to the patients in whom the HERV-E 4-1 env gene expression was not detected. When studying correlation between HERV-E 4-1 env expression and production of IL-1 and IFN, a positive correlation between the studied parameters was established. Thus, taking into account our earlier data on HERV-E 4-1 immunomodulatory properties, as well as literature data concerning the HERV transcripts found in brains of mentally ill patients, along with increase of IL-1 and IFN production in the patients with recurrent depression and positive HERV-E 4-1 env gene expression, and a positive correlation between the HERV-E 4-1 env gene expression and increased level of cytokines involved in formation of pathological events in the nervous system in the patients with depression, one may conclude that activation of HERV-E 4-1 could participate in immunopathogenesis of recurrent depression by stimulating the synthesis of pro-inflammatory cytokines.
Ein mathematisches Modell für einen partiellen demographischen Übergang
Authors: Bacaër Nicolas , Inaba Hisashi , Moussaoui Ali
Published: September 2022

Wir schlagen ein System gewöhnlicher Differentialgleichungen mit homogenen nichtlinearen Termen des ersten Grades vor, um den demografischen Übergang zu modellieren. Es gibt zwei Altersgruppen und zwei Fruchtbarkeitsstufen. Eine geringe Fruchtbarkeit erstreckt sich durch Mimikry auf Erwachsene mit hoher Fruchtbarkeit. Wenn der Mimikry-Koeffizient zunimmt, überschreitet die Bevölkerung zwei Schwellenwerte. Zwischen diesen beiden Schwellenwerten nimmt die Population mit einer stabilen Mischung der beiden Fertilitätsraten exponentiell zu oder ab. Dieser teilweise demografische Übergang ist in einigen Ländern Afrikas südlich der Sahara zu beobachten.

We study a mathematical model for the demographic transition. It is a homogeneous differential system of degree one. There are two age groups and two fertility levels. Low fertility extends by mimicry to adults with high fertility. When the mimicry coefficient increases, the system crosses two thresholds between which the population increases or decreases exponentially with a stable mixture of the two fertility rates. This partial demographic transition is reminiscent of the situation in some countries of sub-Saharan Africa.

On propose un système d'équations différentielles ordinaires avec des termes non linéaires homogènes de degré un pour modéliser la transition démographique. Il y a deux classes d'âge et deux niveaux de fécondité. La fécondité faible s'étend par mimétisme aux adultes avec une fécondité élevée. Lorsque le coefficient de mimétisme augmente, la population traverse deux seuils. Entre ces deux seuils, la population croît ou décroît exponentiellement avec un mélange stable des deux fécondités. Cette transition démographique partielle s'observe dans certains pays d'Afrique subsaharienne.
A Teaching Material of Critical Thinking－Les Misérable
Authors: Choi Yongho
Published: September 2022

Critical thinking, in educational practice, can be more easily approached and trained for students by use of informal contents such as literature, movie, or story telling than by formal logical contents. In this paper, I suggest that Les Misérable, as an example, is one of good teaching materials of critical thinking education. The rationale for this is that familiar literary works arouse common interests of students who have a variety of majors. And critical thinking education with arguments can exert its true value only when it leads students to motivation, theoretical understanding, embodying, and practical application. To show that Les Miserables satisfies this standard, I have introduced first person view summery of the novel and illustrated how various arguments and fallacies can be extracted from the classical literature.
A Study on the Development and Effectiveness of a Psychology Liberal Arts Class Incorporating Self-Directed Learning
Authors: Kang Kyunglee
Published: September 2022

The purpose of this study is to develop a psychology liberal arts class incorporating self-directed learning and to analyze the effects of its implementation. In this study, a psychology liberal arts class connected with the self-directed learning factors was developed for self-directed learning. In order to analyze the effects of liberal arts class, data were collected and analyzed using reflection journal writing and in-depth interviews with 17 university students. The results are as follows. First, at the beginning of the liberal arts class, the process of students attempting to learn was found to be of significant importance regarding the learning process itself, as well as the trial and error process based on past experiences. From the perspective of the Galaxy model, this process is related to cognitive self-directed learning. From the perspective of the education subject, the intention of the learner is founded in education. Second, at the mid point of the liberal arts class, the process of realization among the students in regards to their learning was found to lie in an understanding of the learning phenomenon based on psychology, solving problems related to learning through the connection between psychology and learning science, and the use of teaching media for effective learning. From the perspective of the Galaxy model, this process is related to educational self-directed learning. From the perspective of the education subject, the intentions of learners and instructors are implemented in education. Third, at the end of the liberal arts class, the students’ growth process through learning was found to rest in the areas of their pursuit of value and their pursuit of change. From the perspective of the Galaxy model, this process is related to existential self-directed learning. From the perspective of the education subject, the intention of the learner becomes central in education.
The conclusions are as follows. First, it is necessary for us to develop a liberal arts class with self-directed capabilities that will be required in the era of the 4th Industrial Revolution. Second, such classes need to reflect the learner’s intentions that take into consideration the self-directed learning elements of time, space, exchange, and body elements in the design process of the liberal arts class for self-directed learning capabilities. Third, we need to discuss the appropriate role of the instructor in the operational process of the liberal arts class that possess self-directed learning capabilities.