bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of the Two-Phase Flow Characteristics of a Damping Orifice in an Oleo-Pneumatic Shock Absorber
Authors: Du Siyuan , Zhang Changming , Zhou Ke , Zhao Zhixin
Published: November 2022

The oleo-pneumatic shock absorber involves a complex two-phase flow in the working process. In this paper, a simple oleo-pneumatic shock absorber model was established, and the volume-of-fluid (VOF) two-phase flow model was adopted to accurately simulate the distribution of the two-phase flow field in the shock absorber through the commercial software FLUENT 2020 R2. The accuracy of the simulation model was verified by the method of engineering damping force estimation, and the error of the numerical simulation results compared with the engineering estimation results was 7–8%. By numerical simulation, the influence of different orifice lengths and diameters on the maximum pressure, temperature, velocity and oil damping force inside the shock absorber was studied. The results showed that with the increase of the orifice length, the maximum pressure, flow rate and oil damping force in the shock absorber decreased. The temperature decreased first and then increased, but the overall effect was small. However, according to the oil volume fraction contour, the gas–liquid distribution in the shock absorber with an orifice larger than 15 mm was more chaotic. Increasing the diameter of the orifice had a great impact on the shock absorber. The maximum pressure, flow rate and damping force of the oil inside the shock absorber were sharply reduced, and the temperature continued to rise. These research results can provide reference for the optimization design of oleo-pneumatic shock absorbers.
Modal Selection for Inclined Darcy-Bénard Convection in a Rectangular Cavity
Authors: Rees D. Andrew S. , Barletta Antonio
Published: November 2022

Nonlinear free convection in an inclined rectangular porous cavity heated from below has been studied using a two-dimensional spectral decomposition. The code uses pseudo-arclength continuation to follow solution curves around fold bifurcations. The evolution with inclination of the pattern of convection is complicated and it relies strongly on both the Darcy–Rayleigh number and the aspect ratio of the cavity. When the inclination is large it is generally true that only one cell appears, and that it has a circulation that is consistent with the direction of the buoyancy forces along the heated and cooled boundaries. However, as the inclination decreases back towards the horizontal, this unicellular pattern evolves, sometimes initially via fold bifurcations, into patterns with different numbers of cells. Such evolutions always conserve the parity of the number of cells (such as one cell becoming three and then five, or two cells becoming four), but bifurcations also arise between patterns with different parities. These phenomena are illustrated using a suitable selection of solution curves that show the dependence of the Nusselt number on the inclination.
An Experimental Investigation of Trusting Behaviour
Authors: Mazzoni Clelia , Sbriglia Patrizia
Published: November 2022

In this paper, we present the results of an experiment conducted in Italy on trusting behaviour. Our subjects participated in a trust game and filled in a questionnaire on trust and trustworthiness based on the attitudinal questions reported in the European Value Survey. The aims of the research are twofold. Firstly, using the experimental dataset, we construct two measures of trustworthiness among all recipients in the experiment, one based on the questionnaires’ answers and another based on the strategy method. We then compare the ex-ante behavioural decision to trust (before participants are allocated to a group) with the ex-post decision to trust (after participants are allocated to a group and trustors are informed of the level of trustworthiness of all the recipients who have been randomly allocated to each group). Our main finding is that trust strongly varies once the information is disclosed to trustors. The effect on trust is greater when the strategy method is used. Secondly, we compare the behavioural measure of trust with the attitudinal measures of trust and trustworthiness and find that there is only a weak correlation between the two measures, thus confirming, for the Italian case, similar findings in country-based studies on trust.
Babchi Oil-Based Nanoemulsion Hydrogel for the Management of Psoriasis: A Novel Energy Economic Approach Employing Biosurfactants
Authors: Alam Aftab , Alqarni Mohammed H. , Foudah Ahmed I. , Raish Mohammad , Salkini Mohamad Ayman
Published: November 2022

The current research aimed to assess the Babchi oil nanoemulsion-based hydrogel prepared using biosurfactants through a low-energy emulsification process for the topical management of psoriasis. The emulsification capacity and solubilities of many nanoemulsion constituents such as surfactants, co-surfactants, and oil were considered to determine the range of concentration of the constituents. Pseudoternary phase diagrams were created using the method of titration. Nanoemulgel structure, morphology, micromeritics, conductivity, and viscosity were all optimized. The assessment of the Babchi oil nanoemulgel included particle size, polydispersity index (PDI), drug content, pH, spreadability, rheological management, ex vivo drug study, 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging ability, in vitro drug release, release kinetics, and dermatokinetics. The selected ratios of the surfactant mixture (Smix) taken were 3:1. The entrapment efficiency estimated was 91.298%. The zeta potential of Babchi oil was observed to be −24.93 mV at 25 °C with water as a dispersant, viscosity as 0.887 cP, and material absorption as 0.01 nm. The size distribution of the particle was 108 nm by the intensity and the conductivity observed was 0.03359 mS/cm. The cumulative amount of Babchi oil penetrated and fluxed by nanoemulgel was considered larger (p ≤ 0.05) than the conventional formulations. Skin retention was observed to be good with decreased lag time. The formulation followed the Higuchi Korsmeyer for Fickian Peppas model for in vitro drug release studies. The oil was most effective on the epidermal layer of the skin for treatment. It was established that the Babchi oil nanoemulgel formulation had superior permeability capabilities for topical and transdermal administration and is a viable alternative to traditional formulations.
Complete Chloroplast Genome Sequences of Four Species in the Caladium Genus: Comparative and Phylogenetic Analyses
Authors: Ye Yuanjun , Liu Jinmei , Zhou Yiwei , Zhu Genfa , Tan Jianjun , Xu Yechun
Published: November 2022

Caladiums are promising colorful foliage plants due to their dazzling colors of the leaves, veins, stripes, and patches, which are often cultivated in pots or gardens as decorations. Four wild species, including C. bicolor, C. humboldtii, C. praetermissum, and C. lindenii, were employed in this study, where their chloroplast (cp) genomes were sequenced, assembled, and annotated via high-throughput sequencing. The whole cp genome size ranged from 162,776 bp to 168,888 bp, and the GC contents ranged from 35.09% to 35.91%. Compared with the single large copy (LSC) and single small copy (SSC) regions, more conserved sequences were identified in the inverted repeat regions (IR). We further analyzed the different region borders of nine species of Araceae and found the expansion or contraction of IR/SSC regions might account for the cp genome size variation. Totally, 131 genes were annotated in the cp genomes, including 86 protein-coding genes (PCGs), 37 tRNAs, and eight rRNAs. The effective number of codons (ENC) values and neutrality plot analyses provided the foundation that the natural selection pressure could greatly affect the codon preference. The GC3 content was significantly lower than that of GC1 and GC2, and codons ending with A/U had higher usage preferences. Finally, we conducted phylogenetic relationship analysis based on the chloroplast genomes of twelve species of Araceae, in which C. bicolor and C. humboldtii were grouped together, and C. lindenii was furthest from the other three Caladium species occupying a separate branch. These results will provide a basis for the identification, development, and utilization of Caladium germplasm.
White Sponge Nevus Caused by Keratin 4 Gene Mutation: A Case Report
Authors: Qiao Yahui , Liu Binjie , Bai Ruiqi , Cai Jingwen , Peng Qian
Published: November 2022

White sponge nevus (WSN) is a rare autosomal dominant disease with a family history, often caused by mutations of the keratin 4 (K4) and keratin 13 (K13) genes in patients. It is characterized by frequently occurred white corrugated folds in the bilateral buccal mucosa with soft texture. On histopathological examination, hyperkeratosis of epithelial cells, edema, and vacuolar changes in the spinous cells are observed in the lesions, despite a normal layer of basal cells. WSN should be differentiated from other oral white spot diseases, mainly oral lichen planus, oral candidiasis, oral white edema, and Heck’s disease, to reduce misdiagnosis and unnecessary treatment. At present, there is no specific treatment method. The purpose of this study was to report the clinical data of four WSN patients of the same family with the K4 gene mutation. The occurrence of WSN in a pair of monozygotic twins with very similar clinical presentations was identified for the first time. The gene sequencing results showed that there was a heterozygous deletion (C. 438_440delCAA) in exon 1 of the K4 gene, resulting in an aspartic acid loss in both the proband and his father. Finally, the etiology, pathogenesis, pathological manifestations, clinical manifestations, diagnosis, differential diagnosis, and related treatment methods are discussed to provide a reference for clinical treatment of the disease.
Tonsillectomy in Children with 22q11.2 Deletion Syndrome
Authors: Arganbright Jill M. , Hankey Paul Bryan , Tracy Meghan , Narayanan Srivats , Noel-MacDonnell Janelle , Ingram David
Published: November 2022

Tonsillectomy is one of the most common procedures performed in children, however there are currently no published studies evaluating tonsillectomy in children with 22q11.2 deletion syndrome (22q11DS). With this study, our goal was to investigate the indications, efficacy, and complications of tonsillectomy in a pediatric cohort of patients with 22q11DS. This is a retrospective chart review of patients in our 22q Center’s repository. Inclusion criteria were a diagnosis of 22q11DS and a history of tonsillectomy or adenotonsillectomy. Data collected included: indications for tonsillectomy, preoperative and postoperative polysomnography (PSG) results, and surgical complications. In total, 33 patients were included. Most common indications for tonsillectomy were facilitation with speech surgery (n = 21) and sleep-disordered breathing (SDB)/obstructive sleep apnea (OSA) (n = 16). Average length of stay was 1.15 days. Most patients (69%) had some degree of persistent OSA on postoperative PSG. Complications occurred in 18% of patients and included respiratory distress, hemorrhage, and hypocalcemia. This study demonstrates tonsillectomy was a commonly performed procedure in this cohort of patients with 22q11DS. These data highlight the potential need for close postoperative calcium and respiratory monitoring. The data were limited with respect to PSG outcomes, and future studies are needed to better characterize OSA outcomes and complications in this patient population.
Attitude towards Older People According to Sociodemographic and Educational Variables in Students of a Chilean University
Authors: Yáñez-Yáñez Rodrigo , Parra-Rizo Maria Antonia , McArdle-Draguicevic Nelson , Valdés-Valdés Nathalie , Rojas Gabriel A. , Gamín Leslith , Lorca Paulina , Acevedo-Carrizo Francisca , Zapata-Lamana Rafael , Diaz-Vargas Caterin , Cigarroa Igor
Published: November 2022

Current evidence suggests that attitude towards older people may be associated with sociodemographic and educational variables; hence, a positive attitude towards older people is key when training new university professionals. However, there is little evidence of this association in Chilean university students. The objective was to analyze students from a Chilean university’s attitudes towards older people, according to sociodemographic and educational variables. Analytical and cross-sectional study; 515 students from a Chilean university were consulted online about their attitude towards older people using Kogan’s Attitudes towards Old People scale. Additionally, sociodemographic and educational variables were recorded. The average score for positive attitude was 70.8 (±9.7), while the negative attitude score was 68.3 (±11.6). The total score was 139.1 (±16.6). Mostly, university students perceive themselves with a low-level positive attitude (61.2%). Additionally, older university students (26–42 years old); women; Chileans; students of law, speech therapy, and occupational therapy; students in their final years of the programs; and those who had training in older people outside the university have a more positive attitude towards older people. In Conclusion, a profile of sociodemographic and educational characteristics of students with a lower and higher attitude towards older age was investigated. These results are relevant since the way of seeing the aging process could regulate the training of future professionals and consequently generate changes in dealing with older people. Young people’s perception of ageing would affect the treatment and incorporation of the older people in society and the adaptation of policies in this age group.
Smoking Status and Risk Awareness of Heated Tobacco Product Use among General Dental Practitioners Belonging to the Aichi Dental Association, Japan
Authors: Oya Yukie , Inagaki Koji , Tokumaru Keiji , Watanabe Toshiyuki , Segawa Nobuhiro , Yamamoto Yohei , Takaki Shinsuke , Nimi Takahiro , Okai Makoto , Uchibori Noriyasu , Tabuchi Takahiro , Mitani Akio , Nagao Toru
Published: November 2022

The awareness of healthcare practitioners concerning heated tobacco product (HTP) use risks has been evaluated; however, few studies have investigated general dental practitioners’ awareness regarding HTP-use risks. In this cross-sectional study, we investigated dentists’ awareness of the risks of smoking, particularly HTP use. A self-administered questionnaire, including eight questions on conventional cigarette and HTP smoking/using status and both knowledge and awareness of HTP-use risks, was posted to 3883 dentists belonging to the Aichi Dental Association, Japan, in August 2019. Statistical analysis was performed using the Statistical Package for Social Sciences; statistical significance was set at p < 0.05. We analyzed the data of 1317 dentists (participation rate, 41.6%). The study group included cigarette smokers (11.5%) and HTP users (8.5%), among whom 41.1% were dual users. HTP users were more likely than never smokers/users to correctly perceive HTP-use risks (p < 0.05). This study indicates that in Japan, the proportion of HTP users is higher than that of the general population. It is important to educate not only smokers/users but also never smokers/users on the risks of smoking and using HTPs. Smoking cessation, including ceasing HTP use, and aiming to quit smoking and HTP use among dentists would contribute to appropriate smoking cessation among patients.
Automatic Identification of a Depressive State in Primary Care
Authors: Liu Xiaoqian , Wang Xiaoyang
Published: November 2022

The Center for Epidemiologic Studies Depression Scale (CES-D) performs well in screening depression in primary care. However, people are looking for alternatives because it screens for too many items. With the popularity of social media platforms, facial movement can be recorded ecologically. Considering that there are nonverbal behaviors, including facial movement, associated with a depressive state, this study aims to establish an automatic depression recognition model to be easily used in primary healthcare. We integrated facial activities and gaze behaviors to establish a machine learning algorithm (Kernal Ridge Regression, KRR). We compared different algorithms and different features to achieve the best model. The results showed that the prediction effect of facial and gaze features was higher than that of only facial features. In all of the models we tried, the ridge model with a periodic kernel showed the best performance. The model showed a mutual fund R-squared (R2) value of 0.43 and a Pearson correlation coefficient (r) value of 0.69 (p < 0.001). Then, the most relevant variables (e.g., gaze directions and facial action units) were revealed in the present study.
Effect of Ethylene Sletr1-2 Receptor Allele on Flowering, Fruit Phenotype, Yield, and Shelf-Life of Four F1 Generations of Tropical Tomatoes (Solanum lycopersicum L.)
Authors: Anas Anas , Wiguna Gungun , Damayanti Farida , Mubarok Syariful , Setyorini Dwi , Ezura Hiroshi
Published: November 2022

A longer shelf-life for tomatoes without pleiotropic effects is one of the main goals of breeding programs in tropical countries. Therefore, this study aimed to evaluate the effect of the Sletr1-2 mutant allele on flowering, fruit phenotype, shelf life, and yield-related traits in four F1 hybrids from four tropical tomato genetic backgrounds. The study consisted of four tropical strains, namely ‘Intan’, ‘Mirah’, ‘Ratna’, and ‘Mutiara’, as females crossed with wild type ‘Micro-Tom’ (WT-MT) and mutant Sletr1-2 as males. Each was given three treatments and analyzed separately using a randomized block design with four replications of five samples each. The next test used was the Tukey Alpha 0.05 test. The genetic background of tropical tomatoes affects the phenotype and shelf-life. F1 mutants ‘Intan’ and ‘Ratna’ showed significant results, with a longer shelf-life than F1 WT (10.2 and 14.6 days, respectively). In addition, there were no side effects of the Sletr1-2 mutant allele in the heterozygous form on flowering, fruit phenotype, and yield. In conclusion, the Sletr1-2 allele has the potential to be used in tomato breeding programs in tropical countries.
A Protracted Course of Periorbital Oedema in Infectious Mononucleosis Caused by Epstein–Barr Virus
Authors: Ricardo Daryl
Published: November 2022

Infectious mononucleosis (IM) is a viral disease most commonly caused by the Epstein–Barr virus (EBV). The triad of fever, pharyngitis, and cervical chain lymphadenopathy classically describe this benign condition. Ocular association is also possible, although less commonly reported, and manifests as bilateral periorbital oedema presenting early in the disease process. A case of a fit and well 18-year-old female patient who developed periorbital oedema before the classic triad is presented. Furthermore, her case describes a significantly longer duration of periorbital tissue involvement, contrary to what is described in the current literature. Clinicians should not only recognise periorbital oedema as an initial manifestation of IM but also be alerted of its possible protracted course.
Narrative Review of the COVID-19 Pandemic’s First Two Years in Italy
Authors: Beccia Flavia , Di Pilla Andrea , Causio Francesco Andrea , Federico Bruno , Specchia Maria Lucia , Favaretti Carlo , Boccia Stefania , Damiani Gianfranco
Published: November 2022

Italy was the first country in the western world to be affected by the COVID-19 pandemic, arguably among the worst-affected ones, counting 12 million cases and 150 thousand deaths two years since the first case. Facing new challenges, Italy has enacted different strategies and policies to limit the spread of the SARS-CoV-2 virus and treat those affected by COVID-19. This narrative review provided an overview of factors, measures, and actions that shaped Italy’s first two years of the COVID-19 pandemic by investigating epidemiological data and using a mixed-method approach. This narrative review aimed to summarize the most relevant aspects and measures and analyze available data to provide policymakers and healthcare providers with the instruments to learn from this pandemic and improve their preparedness for future pandemic events. The first two years of the pandemic differ in that, during the first year, significant necessary changes to the way health systems were organized were implemented, increasing healthcare spending and adopting social and physical distancing measures that were stricter than the ones adopted in the second year. However, as the pandemic progressed, increased knowledge of the virus and related variants, as well as the introduction of highly effective vaccines, which were not equally available to the whole population, resulted in a stratification of COVID-19 infections and deaths based on factors such as age, vaccination status, and individual susceptibility to the virus.
A Mixed-Methods Outcomes Evaluation Protocol for a Co-Produced Psychoeducation Workshop Series on Recovery from Psychosis
Authors: Lee Ying Ying , Koo Wei Ler , Tan Yi Fong , Seet Vanessa , Subramaniam Mythily , Ang Suying , Tang Charmaine
Published: November 2022

Co-production in mental health is a relatively new approach to designing and delivering mental health services, which involves collaboration amongst professionals, persons in recovery, and their caregivers to provide services. The aim of this protocol paper is to detail the implementation and evaluation of a co-produced workshop series named Broken Crayons. Collaborating with an early intervention program for first-episode psychosis, the study team and peer volunteers generated a co-production framework based on their experience of co-producing 11 workshops. This paper also outlines a protocol to evaluate Broken Crayons, a psychoeducation workshop series co-created and co-delivered by mental health professionals, persons in recovery, and their caregivers. Indicators on personal recovery, mental wellbeing, community integration, etc., are included as outcomes. Two-tailed, paired t-tests will be used to compare pre- and post-workshop survey data. Focus group discussions will also be conducted to gather subjective experiences of participants of the Broken Crayons workshops. Cost-savings of co-production by Recovery Colleges are discussed. The implications of using co-production to foster citizenry in persons living with first-episode psychosis are discussed in the context of social causation and social drift theories. Taken together, we argued that co-production is not just a passing trend, but a moral imperative for inclusive and equitable mental health service design and delivery.
The Relationship between Physical Activity, Sleep Quality, and Stress: A Study of Teachers during the COVID-19 Pandemic
Authors: Fontana Fabio , Bourbeau Kelsey , Moriarty Terence , da Silva Michael Pereira
Published: November 2022

The COVID-19 pandemic prompted chaotic changes in the daily lives of K-12 teachers, resulting in increased stress and other mental health problems. Limited evidence regarding the relationship between physical activity, sleep, and perceived stress among teachers during the COVID-19 pandemic exists. Therefore, the purpose of this study was to investigate the association between physical activity, sleep quality, and perceived psychological stress among teachers during the COVID-19 pandemic. An online survey measuring physical activity, sleep quality, and perceived psychological stress was distributed across 47 US states between September and October of 2020. Data provided by 635 teachers (mean age: 42 ± 18 years, 74.6% female) were included in the present analysis. Results suggested a negative association between physical activity and perceived psychological stress. Mediation analyses indicated that teachers engaging in high levels of physical activity were more likely to have good quality sleep and, in turn, were less likely to report high levels of perceived stress. Physical activity and sleep-related interventions could help curtail the rising levels of psychological distress amongst K-12 teachers during stressful times such as the COVID-19 pandemic. Teachers, especially those that self-report as female and/or young, report high levels of stress. These high levels of stress are a serious challenge for school districts in terms of attracting and retaining qualified teachers in K-12 classrooms.
Integrated Care Model Salut+Social Assessment by Professionals, Informal Caregivers and Chronic or Social Dependent Patients: A Qualitative Study
Authors: Gavaldà-Espelta Ester , Lleixà-Fortuño Maria del Mar , Aguilar Martín Carina , Pozo Macarena , Ferré-Ferraté Maria , Tomàs-Navarro Begoña , Curto-Romeu Claudia , Lucas-Noll Jorgina , Baucells-Lluis Jordi , Gonçalves Alessandra Queiroga , Ferré-Grau Carmen
Published: November 2022

We explored the views of the professionals (from primary care and social services) and users (caregivers and patients) who participated in the clinical trial of the Salut+Social integrated care model to identify the implementation barriers and facilitators, to assess the impact on health and wellbeing and to obtain an assessment of the program. A qualitative descriptive study with a pragmatic, utilitarian approach was performed. Participants were recruited by purposive and convenience sampling. A focus group (FG) and in-depth interviews were conducted with professionals and users, respectively. Thematic content analysis was employed. A total of 11 professionals and 8 users participated in the FG and interviews, respectively. Seven themes were identified: (1) contextualizing the previous scenario; (2) achievements of the program from the professionals’ perspective; (3) facilitators and barriers of the integrated care model; (4) proposals for improving the integrated care model; (5) users’ assessment of the care received within the program framework; (6) users’ perception of the impact on health and wellbeing; (7) users’ demands for better care. Professionals reported improved coordination between services and highlighted the need for a protocol for emergencies and to strengthen community orientation. Users proposed more frequent home visits. This study shows the acceptability of the new model by professionals and the users’ satisfaction with the care received.
A Preliminary Assessment of Health and Safety in the Automobile Industry in Brunei Darussalam: Workers’ Knowledge and Practice of Organic Solvents
Authors: Hasylin Hazimah , Abdul-Mumin Khadizah H. , Pg-Hj-Ismail Pg-Khalifah , Trivedi Ashish , Win Kyaw Naing
Published: November 2022

Automobile industries worldwide extensively use organic solvents. Yet, limited studies have examined the health and safety of handling these solvents, which can only be assured if workers have appropriate knowledge and demonstrate safe practices. A cross-sectional study was conducted to preliminary explore the knowledge and practice among workers who are involved in handling organic solvents in the automobile industry in the largest urban district in Brunei Darussalam. Qualitative data were sourced from open-ended questions, observations, and pictorial evidence through still photographs. Quantitative analysis showed that 75% of the workers practice reading labels, 94.1% use fully covered clothes, 82.4% wear gloves, and 98.5% practice proper hand washing. Furthermore, 98.5% of workers cover container lids. The qualitative analysis illustrated that workers have general knowledge of materials containing solvents but could not identify the exact solvents, the harmful effects of the solvents, pathophysiology, and harmful effects on specific body systems. Health and safety were found to be practiced, albeit not consistently. Health and Safety Authorities in Brunei Darussalam must review and enforce specific policies on the use of organic solvents so that they can be practiced consistently and safely in the automobile industry. Cooperation and collaboration in adhering to the policies are mandatory to ensure health and safety at work.
Effect of Normalization Methods on Accuracy of Estimating Low- and High-Molecular Weight PAHs Distribution in the Soils of a Coking Plant
Authors: Yuan Yumin , Yang Kai , Cheng Lirong , Bai Yijuan , Wang Yingying , Hou Ying , Ding Aizhong
Published: November 2022

Mapping spatial distribution of soil contaminants at contaminated sites is the basis of risk assessment. Hotspots can cause strongly skewed distribution of the raw contaminant concentrations in soil, and consequently can require suitable normalization prior to interpolation. In this study, three normalization methods including normal score, Johnson, and Box-Cox transformation were performed on the concentrations of two low-molecular weight (LMW) PAHs (i.e., acenaphthene (Ace) and naphthalene (Nap)) and two high-molecular weight (HMW) PAHs (i.e., benzo(a)pyrene (BaP) and benzo(b)fluoranthene (BbF)) in soils of a typical coking plant in North China. The estimating accuracy of soil LMW and HMW PAHs distribution using ordinary kriging with different normalization methods was compared. The results showed that all transformed data passed the Kolmogorov-Smirnov test, indicating that all three data transformation methods achieved normality of raw data. Compared to Box-Cox-ordinary kriging, normal score-, and Johnson-ordinary kriging had higher estimating accuracy of the four soil PAHs distribution. In cross-validation, smaller root-mean-square error (RMSE) and mean error (ME) values were observed for normal score-ordinary kriging for both LMW and HMW PAHs compared to Johnson- and Box-Cox-ordinary kriging. Thus, normal score transformation is suitable for alleviating the impact of hotspots on estimating accuracy of the four selected soil PAHs distribution at this coking plant. The findings can provide insights into reducing uncertainty in spatial interpolation at PAHs-contaminated sites.
Fault Diagnosis and Maintenance Countermeasures of Transverse Drainage Pipe in Subway Tunnel Based on Fault Tree Analysis
Authors: Liu Shiyang , Zhang Xuefu
Published: November 2022

Transverse drainage pipe, one of the main channels of groundwater behind the lining of subway tunnels, plays an important role in the safety and stability of the tunnel lining structure. For the problem of blocked transverse drainage pipe in a subway tunnel, a fault tree model of blocked transverse drainage pipe in Chongqing subway tunnel was constructed in this paper, the quantitative and qualitative analysis of fault tree was conducted, and countermeasures for maintenance of transverse drainage pipe were proposed. The study finds that, (1) the chemical type of groundwater was mainly CaHCO3; most of the groundwater is strongly alkaline with pH greater than 8; the groundwater temperature is 20 ± 3 °C; (2) the basic events of blocked transverse drainage pipe have 3 minimum cut sets, and the basic events concrete slurry enters the drainage pipe; groundwater temperature, groundwater pH value, and concentration of anions and cations in groundwater were the main fault factors of blocked transverse drainage pipe; (3) preventive maintenance of transverse drainage pipe during tunnel construction includes construction quality control of drainage pipe and application of anti-crystallized blocking drainage pipe; preventive maintenance of transverse drainage pipe during tunnel operation includes monitoring of groundwater ion concentration, pH, and temperature; and maintenance treatment of transverse drainage pipe during tunnel operation includes physical treatment techniques, such as ultrasonic resonance, and chemical treatment techniques, such as acid-base neutralization reaction. The results of the study have certain guiding significance for the design, construction, and operation of transverse drainage pipe in subway tunnels.
Effects of Multi-Component Exercise on Sleep Quality in Middle-Aged Adults
Authors: Ai Jing-Yi , Kuan Garry , Juang Linda Ya-Ting , Lee Ching-Hsiu , Kueh Yee-Cheng , Chu I-Hua , Geng Xiao-Ling , Chang Yu-Kai
Published: November 2022

Sleep is a crucial factor in healthy aging. However, most middle-aged adults experience high levels of sleep disorders. While previous findings have suggested exercise training could benefit the quality of sleep, the effects of multi-component exercise on sleep quality are less examined. Accordingly, the current study aimed to assess the effectiveness of a multi-component exercise program on the quality of sleep among middle-aged adults. Twenty-four middle-aged adults were randomly assigned either to a multi-component exercise (MCE) group or a control group. The participants in the MCE group attended a 90-min session per week for 12 weeks. The control group was instructed to maintain their daily routine for 12 weeks. The primary outcome was the sleep quality evaluated by the Pittsburgh Sleep Quality Index (PSQI). The secondary outcome was physical fitness, including muscular strength and endurance, balance, and flexibility. Regarding sleep quality, the global mean score (p = 028), sleep disturbances (p = 011), and sleep efficiency (p = 035) of the PSQI scores were significantly reduced in the MCE group after the 12-week intervention. Regarding physical fitness, the flexibility of the MCE group improved significantly after the intervention (p = 028), yet, no significant change was observed in the control group. Additionally, the muscular strength of the control group declined significantly after the 12-week period (p = 034). Our results revealed the effectiveness of the MCE intervention in improving sleep quality and physical fitness in middle-aged adults. Further studies using larger sample sizes, objective measures of sleep quality, different types of exercise training, as well as different populations, are warranted to extend our current findings.
Assessment of the Functional Level of Independence in Individuals with Mental Disabilities as Part of Special Education Diagnostics: Case Studies
Authors: Vostrý Michal , Lanková Barbora , Pešatová Ilona , Müllerová Lenka , Vomáčková Helena
Published: November 2022

In this study we focus on the application of standardized tests aimed at evaluating the functional degree of independence in children (client 1, WeeFIM test; and client 2, FIM test) in special education diagnostics. The target group consisted of two clients with a diagnosis of mental functional diversity (n = 2; client 1: mild mental retardation, according to ICD-10: F70, aged 6.5 years; and client 2: moderate mental retardation, according to ICD-10: F71, aged 13.4 years). Special pedagogical intervention was primarily applied to the clients, focusing on identified deficits in the areas of cognitive, motor, and social skills. The presented results demonstrate the importance of the application of these tests in special pedagogy. An improvement in the observed indicators of the given tests was demonstrated for both probands after the intervention. The aim of this article was to draw attention to the suitability of using functional independence tests in special pedagogical practices. The authors discuss the further implications of this application for future practice.
Burden and Risk Factors of Melioidosis in Southeast Asia: A Scoping Review
Authors: Selvam Kasturi , Ganapathy Thanasree , Najib Mohamad Ahmad , Khalid Muhammad Fazli , Abdullah Nor Azlina , Harun Azian , Wan Mohammad Wan Mohd Zahiruddin , Aziah Ismail
Published: November 2022

This scoping review aims to provide a comprehensive overview of human melioidosis in Southeast Asia as well as to highlight knowledge gaps in the prevalence and risk factors of this life-threatening disease using available evidence-based data for better diagnosis and treatment. Preferred Reporting Items for Systematic Review and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) was used as the guideline for this review. The literature search was conducted on 23 March 2022 through two electronic databases (PubMed and Scopus) using lists of keywords referring to the Medical Subject Headings (MeSH) thesaurus. A total of 38 articles related to human melioidosis were included from 645 screened articles. These studies were carried out between 1986 and 2019 in six Southeast Asian countries: Thailand, Cambodia, Malaysia, Myanmar, Singapore, and Vietnam. Melioidosis has been reported with a high disease prevalence among high-risk populations. Studies in Thailand (48.0%) and Cambodia (74.4%) revealed disease prevalence in patients with septic arthritis and children with suppurative parotitis, respectively. Other studies in Thailand (63.5%) and Malaysia (54.4% and 65.7%) showed a high seroprevalence of melioidosis among Tsunami survivors and military personnel, respectively. Additionally, this review documented soil and water exposure, diabetes mellitus, chronic renal failure, thalassemia, and children under the age of 15 as the main risk factors for melioidosis. Human melioidosis is currently under-reported in Southeast Asia and its true prevalence is unknown.
Parental Educational Anxiety during Children’s Transition to Primary School in China
Authors: Liu Qianqian , Hong Xiumin , Wang Mei
Published: November 2022

Children’s transition from preschool to primary school has long been recognized as a particularly challenging period that can induce parental educational anxiety. As a true portraiture of Chinese parenting, educational anxiety during this transition has attracted considerable attention, given its detrimental effects on children’s development and education. This study was aimed at identifying the characteristics of parental educational anxiety and its influencing factors during children’s transition to primary school in China. We examined parental educational anxiety and parental educational experience through a questionnaire survey. The sample comprised 26,295 families with children in grade one distributed across nine cities in five provinces. The results indicate that (1) Chinese parents experience some degree of educational anxiety during their children’s transition to primary school and are more worried about their children’s learning and social adaptation processes than about how the curriculum is taught; (2) scores for parental educational anxiety varied significantly across different regions and urban/rural areas; (3) family socioeconomic status, parents’ educational concepts, preschools’ entrance preparation work, and primary school enrollment adaptation work are all important factors influencing parental educational anxiety during this transition. Our findings highlight the prevalence of parental educational anxiety in China and the need for effective measures to facilitate a smooth transition.
Effect of COVID-19 Lockdown on Cardiovascular Health in University Students
Authors: Bielec Grzegorz , Kwaśna Anna
Published: November 2022

Background: A decrease in physical activity levels among university students during the COVID-19 pandemic is well-documented in the literature. However, the effect of lockdown restrictions on cardiovascular fitness has not been thoroughly investigated. Methods: The aim of the study was to assess the possible changes in cardiovascular fitness among university students during a 14-week period of the COVID-19 pandemic. Thirteen female and seven male tourism and recreation students participated in the study. Examinations were conducted in November 2020 and in February/March 2021. Students performed the PWC170 test on a cycling ergometer. Maximal oxygen consumption was calculated based on the PWC170 test results. Blood pressure and heart rate were measured at rest, as well as in the 1st and 5th minute of post-exercise recovery. Results: No substantial changes were observed in maximal oxygen consumption level when comparing autumn and winter indices. Male students presented elevated blood pressure whereas female students presented normal blood pressure. Heart-rate and blood-pressure indices did not show substantial alternations in examined students during analyzed period. Conclusions: Fourteen weeks of lockdown had little effect on the cardiovascular health of tourism and recreation students.
Impact of Sleep Fragmentation on Cognition and Fatigue
Authors: Benkirane Oumaïma , Delwiche Bérénice , Mairesse Olivier , Peigneux Philippe
Published: November 2022

Sleep continuity and efficacy are essential for optimal cognitive functions. How sleep fragmentation (SF) impairs cognitive functioning, and especially cognitive fatigue (CF), remains elusive. We investigated the impact of induced SF on CF through the TloadDback task, measuring interindividual variability in working memory capacity. Sixteen participants underwent an adaptation polysomnography night and three consecutive nights, once in a SF condition induced by non-awakening auditory stimulations, once under restorative sleep (RS) condition, counterbalanced within-subject. In both conditions, participants were administered memory, vigilance, inhibition and verbal fluency testing, and for CF the TloadDback, as well as sleep questionnaires and fatigue and sleepiness visual analog scales were administered. Subjective fatigue increased and sleep architecture was altered after SF (reduced sleep efficiency, percentage of N3 and REM, number of NREM and REM phases) despite similar total sleep time. At the behavioral level, only inhibition deteriorated after SF, and CF similarly evolved in RS and SF conditions. In line with prior research, we show that SF disrupts sleep architecture and exerts a deleterious impact on subjective fatigue and inhibition. However, young healthy participants appear able to compensate for CF induced by three consecutive SF nights. Further studies should investigate SF effects in extended and/or pathological disruption settings.
Conflicting HIV/AIDS Sex Education Policies and Mixed Messaging among Educators and Students in the Lower Manya Krobo Municipality, Ghana
Authors: Ocran Benedict , Talboys Sharon , Shoaf Kimberley
Published: November 2022

While school-based comprehensive sex education (CSE) is effective in HIV prevention among young people ages 10–24 years, Ghana’s national sexual and reproductive health education policy promotes abstinence. Meanwhile, the Ministry of Health’s HIV prevention programs provide more comprehensive school-based education. This qualitative study evaluated the HIV/AIDS education program in the Lower Manya Krobo Municipality to assess the perspectives of students and educators in 10 schools on school-based sexual and reproductive health programs, including HIV/AIDS education and conflicting HIV/AIDS sex education policies. HIV prevalence in the Lower Manya Krobo Municipality of Ghana was more than twice the national average at 5.64% in 2018, and prevalence among youth in the municipality aged 15–24 was the highest in the nation at 0.8%. Educators have mixed feelings regarding abstinence-based and CSE approaches. However, students generally endorse abstinence and describe the limitations of condom use. Ambiguity in overarching policies is identified as a factor that could influence the orientation of school-based health educators, create disharmony in sex education interventions, introduce confusing sex education messages to young people, and create a potentially narrow curriculum that limits the gamut of HIV/AIDS sex education to exclude young people’s risky sexual behaviours and diverse teaching and implementation strategies. Policies and the scope of sex education should be realigned to ensure the transparent implementation of HIV/AIDS sex education programs in Ghana.
Incentives behind and Experiences of Being Active in Working Life after Age 65 in Sweden
Authors: Bjuhr Marie , Engström Maria , Welmer Anna-Karin , Lindberg Magnus , Sjölund Britt-Marie
Published: November 2022

Since individual and societal expectations regarding the possibility of an extended working life after the expected retirement age are increasing, research on sustainable working life combined with healthy ageing is needed. This study explores the incentives behind and experiences of an extended working life after the expected retirement age of 65 among Swedish people. The inductive qualitative content analyses are based on 18 individual semi-structured interviews among persons 67–90 years old with varying characteristics and varying experiences of extended working lives. The analyses revealed that working contributed to (1) sustained internal resources, i.e., cognitive function, physical ability and increased vigor; (2) sustained external resources, i.e., social enrichment, better daily routines and economic benefits; (3) added meaningfulness to life, i.e., being needed, capability and satisfaction with working tasks. Meanwhile, having flexible working conditions enabled a satisfying balance between work and leisure. Altogether, these different aspects of overall health and working life were interpreted as contributing to increased feelings of vitality, the innermost dimension of health. Conclusions: regardless of biological age, our results indicate that being able to remain active in working life can be beneficial to vitality and could make these results valuable for both health-care personnel and employers.
The Effect of Resistance Training on the Rehabilitation of Elderly Patients with Sarcopenia: A Meta-Analysis
Authors: Zhao Haotian , Cheng Ruihong , Song Ge , Teng Jin , Shen Siqin , Fu Xuancheng , Yan Yi , Liu Chang
Published: November 2022

Resistance training is considered to be an efficient treatment for age-related sarcopenia and can improve muscle strength and quality in patients. However, there are currently no recommendations on resistance training parameters to improve muscle strength and quality in elderly patients with sarcopenia. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) and included 13 eligible RCTs. Resistance training significantly improved grip strength, gait speed, and skeletal muscle index in patients with age-related sarcopenia, and kettlebell was found to be the most effective modality. However, it is noteworthy that the elastic band is also a recommended form of resistance training considering that the kettlebell intervention was tested in only one study, while the elastic band was confirmed by multiple studies. Elastic band training (Hedges’s g = 0.629, 95%CI = 0.090–1.168, p < 0.05) (40–60 min per session, more than three times per week for at least 12 weeks) was the most efficient training method. Thus, resistance training can significantly improve muscle strength and muscle quality in elderly patients with sarcopenia. In addition, moderate-intensity resistance training using elastic bands may be the best training prescription for elderly patients with sarcopenia.
Deleterious Effect of Air Pollution on Human Microbial Community and Bacterial Flora: A Short Review
Authors: Gupta Nishant , Yadav Virendra Kumar , Gacem Amel , Al-Dossari M. , Yadav Krishna Kumar , Abd El-Gawaad N. S. , Ben Khedher Nidhal , Choudhary Nisha , Kumar Pankaj , Cavalu Simona
Published: November 2022

A balanced microbiota composition is requisite for normal physiological functions of the human body. However, several environmental factors such as air pollutants may perturb the human microbiota composition. It is noticeable that currently around 99% of the world’s population is breathing polluted air. Air pollution’s debilitating health impacts have been studied scrupulously, including in the human gut microbiota. Nevertheless, air pollution’s impact on other microbiotas of the human body is less understood so far. In the present review, the authors have summarized and discussed recent studies’ outcomes related to air pollution-driven microbiotas’ dysbiosis (including oral, nasal, respiratory, gut, skin, and thyroid microbiotas) and its potential multi-organ health risks.