bluuebunny/crossref_metadata_2025 huggingface dataset:
ВОПРОСЫ ЦИФРОВОЙ ТРАНСФОРМАЦИИ В ТРАСПОРТНОЙ ОТРАСЛИ: АКТУАЛИЗАЦИЯ РАЗВИТИЯ СПРОСА НА ЦИФРОВЫЕ ТЕХНОЛОГИИ
Authors: К.В. Борзенко
Published: November 2024

Предметом выступает уточнение ситуации с глубиной цифровых преобразований в отрасли транспорта в России и имеющихся в данном отношении перспективах. Целью статьи является детализация прогноза прироста спроса на цифровые технологии в отрасли транспорта с детерминацией возможных барьеров и направлений их преодоления. Метод: сопоставление мнений экспертов, специализированных организаций в отношении глубины цифровых изменений в отрасли транспорта, анализ реализованных проектов, оценка тренда прироста спроса на цифровые технологии в отрасли. Результаты статьи имеют прикладное значение, они состоят в обосновании преобразований инфраструктуры, развития нормативных требований и предоставления финансовой помощи в виде активизации льготных кредитов для малых и средних предпринимателей, предприятий, которые успешно внедрили и/или разработали востребованные цифровые решения, возможные к масштабированию в отрасли.

Subject is to clarify the situation with depth of digital transformations in transport industry in Russia and prospects available in this regard. Purpose of article is to detail the forecast of increase in demand for digital technologies in transport industry with determination of possible barriers and ways to overcome them. Method: comparison of opinions of experts, specialized organizations regarding the depth of digital changes in transport industry, analysis of implemented projects, assessment of trend of growth in demand for digital technologies in industry. Results of work are of applied importance, they consist in substantiating infrastructure transformations, development of regulatory requirements and provision of financial assistance in form of activation of preferential loans for small and medium-sized entrepreneurs, enterprises that have successfully implemented and/or developed in-demand digital solutions that can be scaled in industry.
РАЗВИТИЕ ЛОГИСТИЧЕСКОЙ СИСТЕМЫ ВЕТРОЭНЕРГЕТИКИ В РОСТОВСКОЙ ОБЛАСТИ
Authors: М.А. Мацедонский
Published: November 2024

В статье охарактеризовано моделирование процесса развития логистической системы ветроэнергетики на юге России, проанализирована ситуация с несколькими функционирующими а также проектируемыми для возведения в будущем в эксплуатацию ветропарками в Ростовской области; представлено мнение, согласно которому новые объекты генерации на основе возобновляемых источников энергии, должны заполнить выбытие устаревших фондов; рассмотрены новые фонды генерации смежных регионов а так же перспективы развития логистической системы ветроэнергетики на исследуемой территории.

Article describes the modeling process of development of wind energy logistics system in south of Russia, analyzes the situation with several functioning and projected for future construction of wind farms in Rostov region; presented the view that new generation facilities based on renewable energy sources, should fill the retirement of obsolete funds; considered new generation funds adjacent regions as well as prospects for development of logistics system of wind energy in study area.
РЕГУЛЯТОРЫ ЗЕРНОВОГО РЫНКА РОССИЙСКОЙ ФЕДЕРАЦИИ В 2023 Г.
Authors: Т.А. Салтанова , И.А. Митина
Published: November 2024

Регулирование зернового рынка страны представляет собой дискуссионный вопрос, поскольку затрагивает интересы всех участников национальной агропродовольственной системы. Необходимо соблюдение таких зависимостей, как обеспечение продовольственной безопасности страны и экспорт зерна, увеличение доходности зернового сектора и стимулирование развития животноводства. Несбалансированность данных процессов негативно отражается на достижении целевых установок в развитии агропромышленного комплекса в целом. В статье рассмотрены основные аспекты регулирования зернового рынка России в ситуации расширения предложения, роста затрат растениеводов. Статья посвящена практическим вопросам функционирования и регулирования зернового рынка в условиях расширенного предложения, стабилизации цен на уровне предшествующих периодов без учета роста затрат производителей. Обоснована необходимость применения административных и экономических регуляторов зернового рынка в целях повышения эффективности его функционирования и поступательного развития всей агропродовольственной системы.

Regulation of country's grain market is debatable issue, since it affects the interests of all participants in national agro-food system. It is necessary to comply with such dependencies as ensuring the country's food security and grain exports, increasing the profitability of grain sector and stimulating the development of animal husbandry. Imbalance of these processes negatively affects the achievement of targets in development of agro-industrial complex as a whole. Article examines the main aspects of regulating the grain market of Russia in situation of expanding supply, rising costs of plant growers. Article is devoted to practical issues of regulating the functioning and regulation of grain market in conditions of expanded supply, price stabilization at the level of previous periods without taking into account the growth of producers' costs. Necessity of applying administrative and economic regulators of grain market in order to increase the efficiency of its functioning and progressive development of entire agro-food system is substantiated.
Integration of Reading and Writing: Curriculum Logic and Practical Pathways
Authors: Sun Qiming , Liang Yanlong
Published: November 2024

Integration of reading and writing refers to the organic interaction between reading and writing, wherein both mutually promote and enhance quality and efficiency. Implementing this integration in Chinese language instruction aims to cultivate students' language literacy. From a curriculum development perspective, integrated reading and writing is increasingly favored by curriculum standards, textbooks, and high school entrance exams. In practice, using texts as models can guide students to learn observational techniques, choose appropriate modes of expression centered around a theme, and master basic textual structures. Meanwhile, writing can clarify the purpose of reading, enhance reading interest, and deepen reading comprehension.
Influence of nursing interns’ resilience on burnout: Mediating effects of well-being
Authors: Li Juan , Li Minrui , Ye Junli , Zhai Huimin
Published: November 2024

Objective: This study examined the relationship between well-being, psychological resilience, and burnout among nursing interns in China.Methods: A cross-sectional study was carried out at 2 tertiary hospitals in Guangdong Province, China. Data were collected from 360 nursing interns using a structured questionnaire, and structural equation modeling was used to analyze the correlation between well-being, resilience, and burnout.Results: Participants’ burnout score was in the upper range (mean [M]=12.748, standard deviation [SD] = 6.654). Burnout was negatively correlated with resilience (r = -0.477, p < .01) and well-being (r = -0.573, p < .01). Well-being mediated the relationship between resilience and burnout.Conclusions: Resilience and well-being are inversely correlated with burnout, and well-being mediates the relationship between resilience and burnout. Improving well-being can reduce burnout risk and improve resilience among nursing interns. To prevent burnout among nursing interns, nursing managers should aim to improve their well-being by optimizing the work environment, promoting the cohesion of the nursing team, actively guiding and providing necessary help, and supporting the development of each intern’s nursing career.
Determination of Vitamin C Concentration in Various Fresh Orange and Lemon Samples from Janzour Region Using Volumetric Titration
Authors: Fatma Hebail
Published: November 2024

Vitamin C is an essential nutrient crucial for human health, playing a vital role in numerous physiological processes, including immune system support and collagen synthesis. Citrus fruits, such as oranges and lemons, are recognized as rich sources of this vitamin. The primary purpose of this study is to determine the vitamin C concentration in various fresh orange and lemon juices. The samples were randomly collected from the local market in Janzour. The study included 18 samples representing 6 different citrus varieties (3 samples per variety). Vitamin C concentration was statistically estimated using a titrimetric method with a standardized solution of 2,6-dichlorophenolindophenol (DCPIP) as the titrant. The obtained results revealed some kind of variations in vitamin C content among different citrus varieties and even within samples of the same variety. Abu Surah orange samples exhibited the highest vitamin C concentration (mean range: 38.9-41.6 mg/dl), while sweet orange samples had the lowest (mean range: 5.1- 8.5 mg/dl). Vitamin C concentrations in other varieties ranged as follows: Sour orange: 9.22-24.9 mg/dl, Mandarin: 9.0 -16.2 mg/dl, Tarocco: 28.2-33.3 mg/dl, and Lemon: 14.5-15.8 mg/dl. These results showed evidently that vitamin C levels were varied even within the same sample type. Such variations would draw attention to the importance of choosing varieties when searching for food sources of this vital nutrient.
SOLUSI PENANGANAN PENCEMARAN AIR SUNGAI AKIBAT SISTEM SANITASI YANG BURUK DI KAMPUNG ANYAR, BULELENG,BALI
Authors: I Wayan Selva Paryanta , Tamiarta Kori , Pradnyaningrum Siskha
Published: November 2024

Kampung Anyar merupakan salah satu dari 8 permukiman yang ditetapkan sebagai permukiman kumuh di kabupaten Buleleng menurut surat keputusan bupati Nomor 050/74/HK/2016. Tergolongnya sebagai permukiman kumuh dikarenakan karakteristik dan permasalahan-permasalahan permukiman kumuh ada pada Kampung Anyar ini, baik secara fisik maupun non fisik. Lokasi yang berdekatan dengan pantai/laut menyebabkan posisi air tanah menjadi lebih tinggi, sekitar 2 meter dari permukaan tanah sehingga warga kesulitan dalam membuat saluran pembuangan tinja dan tidak memungkinkan untuk penggalian septik tank. Maka warga  di kampung anyar menggunakan toilet umum yang posisinya berada di atas sungai dan tinja/kotoran manusia akan langsung dibuang ke sungai, sehingga menimbulkan pencemaran terhadap lingkungan sungai. Maka dari itu, tujuan dari penulisan jurnal ini adalah untuk memberikan solusi dari permasalahan sanitasi (septic tank) tersebut dan sistem pembuangan yang lebih ramah lingkungan. Metoda penelitian yang digunakan adalah kualitatif dengan cara pengumpulan data melalui survei lapangan, wawancara dan studi literatur, serta metoda analisis menggunakan pendekatan kualitatif. Hasil dari penelitian ini adalah penggunaan septic tank biofilter, dimana posisinya tidak perlu terlalu dalam sehingga masih aman dari air tanah dan untuk meminimalkan dampak terhadap lingkungan, karena menggunakan metode pengolahan aerob / anaerob dengan sistem filtrasi, yang memungkinkan tinja diolah dan diurai di dalam tabung septic tank biofil tanpa memerlukan rembesan seperti septic tank konvensional biasa, sehingga air tanah maupun air sungai tidak tercemar.
TIPOLOGI TATA RUANG DALAM RUMAH ADAT DESA NUALAIN BELU
Authors: Solissa Arfie , Kaat Yosua Yusuf , Hakeng Louis SPP
Published: November 2024

Abstrak: Nualaian adalah salah satu desa yang terletak di kecamatan Lamaknen selatan kabupaten Belu Provinsi Nusa Tenggara Timur. Nualain, yang kini menjadi situs budaya Belu, sejak dahulu dihuni 32 suku yang berasal dari tiga rumah suku atau dalam bahasa Bunak disebut Gamal, dimulai dari rumah suku raja yang disebut Gamal Mone Sogo, rumah suku wakil raja atau Gamal Mone Walu dan rumah suku panglima perang yang disebut Gamal Suba. Setiap Gamal menggambarkan kasta dan ciri khas dari setiap suku yang sudah ada di desa adat Nualain. Tujuan penelitian ini adalah untuk memperoleh pemahaman yang lebih baik dan mendalam mengenai tipologi tata ruang dalam rumah adat desa Nualain. Metode yang digunakan dalam penelitian Tipologi Tata Ruang dalam Rumah Adat Desa Nualain ini adalah metode penelitian deskriptif kualitatif, dengan pendekatan fenomenologi yaitu pendekatan yang melihat dan merekam fenomena yang terjadi di lokasi penelitian. Hasil penelitian terdapat 2 pola ruang yaitu pembagian pola ruang secara horizontal dan vertikal.
PENILAIAN KUALITAS RUMAH BANTUAN PASKA TSUNAMI DI BANDA ACEH, INDONESIA SETELAH SATU DEKADE DITEMPATI
Authors: Adamy Aulina , Meillyta Meillyta , Fata Abrarul , Sukena Ilham
Published: November 2024

Dari seluruh kabupaten atau kota di Aceh, Banda Aceh sebagai ibu kota merupakan daerah yang paling parah terkena dampak gempa dan tsunami pada tahun 2004. Perumahan merupakan proyek bantuan dengan jumlah terbesar dan desain yang beragam karena bersumber dari berbagai bantuan. Setelah 15 tahun, kelayakan perumahan tersebut terlihat lebih jelas. Tujuan dari penelitian ini adalah untuk mengetahui kualitas rumah yang dihuni setelah lebih dari satu dekade melalui pengukuran kualitas lingkungannya. Umumnya, rumah bantuan terlihat bagus pada saat serah terima, tetapi kualitas sebenarnya perlu diuji setelah beberapa tahun ditempati. Penelitian dilakukan di Kecamatan Meuraxa dengan memilih lima desa secara acak. Sebanyak 45 hunian dengan 9 jenis desain dievaluasi. Metode penelitian kuantitatif dengan pengukuran mekanis untuk intensitas cahaya, kelembaban, dan suhu. Hasil penelitian menunjukkan bahwa secara umum rumah bantuan belum memenuhi standar lingkungan rumah sehat yang ditetapkan pemerintah. Rumah yang dibangun oleh P2KP menunjukkan kinerja lingkungan dan kualitas bangunan yang lebih baik, sedangkan rumah dari YLKI dan BRR justru sebaliknya. Setelah lebih dari satu dekade, nampaknya kombinasi bantuan perumahan berkualitas rendah dan penduduk berpenghasilan rendah berkontribusi terhadap terbentuknya permukiman kumuh. Untuk mendapatkan pemahaman yang komprehensif mengenai rekonstruksi rumah di Aceh dan Nias pasca Tsunami, penelitian di masa depan perlu mencakup lebih banyak variasi desain rumah dengan cakupan wilayah yang lebih luas. Tingginya angka kejadian Infeksi Saluran Pernafasan Akut (ISPA) di Banda Aceh kemungkinan disebabkan oleh buruknya kualitas lingkungan rumah bantuan sehingga diperlukan kajian korelasi khusus di masa depan.
Major considerations of gingivoplasty: a concise systematic review
Authors: Evangelista Iasmim Milene , Candido Lauani Regina , Araújo José Janci Siqueira de , Scriboni Andreia Borges
Published: November 2024

Introduction: In the scenario of gingivoplasty, well-being is directly related to health, people with a balanced smile, between health and beauty, tend to smile more and this generates a condition of well-being. In gingival correction, process-specific techniques are used for each case, thus individualizing the patient and the proposed treatment, correcting not only the aesthetics but also the patient as a whole. Objective: This systematic review study described the techniques used to correct a gummy smile, with the gingivoplasty technique being selected. Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from March to June 2024 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: 78 articles were found and 15 articles were evaluated in full and 06 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 25 studies with a high risk of bias and 22 studies that did not meet GRADE and AMSTAR-2. Most studies did not show homogeneity in their results, with X2=87.5%>50%. It was concluded that applications of injectable platelet-rich fibrin have shown positive effects on epithelial wound healing after gingivectomy and gingivoplasty operations. A patient with a meso facial profile, compatible with hypertonic lips, improves our favorable prognostic acceptability with a lower risk of relapse and dissatisfaction. Bone-removing gingivoplasty is indicated for cases where removal of the gingival band only reduces the gingival sulcus invading the biological distance and thus needs to remove the bone for soft tissue stability.
Major approaches oral cancer and bucomaxillofacial surgical procedures: a concise systematic review
Authors: Freitas Ricardo Barbosa de , Aredes Gisele Delmaschio Amigo , Beneti Igor Mariotto
Published: November 2024

Introduction: In oral neoplasms, squamous cell carcinomas (SCCs) account for more than 90% of cases. SCCs can have several levels of differentiation and often give rise to lymph node metastases. Clinical recognition and evaluation of oral mucosal lesions can detect up to 99% of oral cancers. Objective: It was sought to list the main approaches to treating oral cancer, both in early identification and in bucomaxillofacial surgical procedures. Methods: The systematic review rules of the PRISMA Platform were followed. The search was conducted from July to August 2024 in the Web of Science, Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 115 articles were found. 23 articles were fully evaluated and 14 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 35 studies with a high risk of bias and 32 that did not meet GRADE and AMSTAR-2. Most studies presented homogeneity in their results, with X2=88.8%>50%. It was concluded that oral mucosa cancer is one of the most common oral cancers and has a poor prognosis. This can confirm that the planned dental treatment performed during oral cancer treatment produces an improvement in the quality of life of oral cancer patients. The indication for bucomaxillofacial surgery should be meticulously planned. In addition, dentists should consider a patient's ongoing cancer therapy for those patients who come to the dentist while receiving cancer treatment. The use of nomograms in clinical practice should bring significant benefits to patients with oral mucosa cancer.
A novel tucker decomposition driven taxi travel demand forecasting algorithm
Authors: Chu Benjia , Yan Hongyu
Published: November 2024

This research aims to enhance taxi travel demand forecasting for sustainable urban traffic management and planning. We extend the Seasonal Autoregressive Integrated Moving Average model into a high-dimensional tensor form by treating the urban transport network as a Euclidean space and introducing Tucker decomposition. This novel approach, both theoretically significant and practically applicable, represents time series data as tensors to better capture multimodal structures and correlations, improving predictive accuracy. Tucker decomposition reduces computational complexity and memory requirements, making it ideal for large-scale urban traffic network prediction. Experiments on six real-world datasets show that the model’s MAE and RMSE are reduced by about 39.43% and 27.01% on average, respectively, compared to the baseline model. Notably, the model is computationally very efficient and takes only a relatively short time to train., suitable for real-time traffic management, congestion mitigation, and resource optimization. In summary, this work innovates time series analysis, providing an efficient and precise tool for urban traffic management and planning, contributing to sustainable urban transportation advancement.
Effect of Provenance Variation on Growth Performance of Indigenous Highland Bamboo Species (Arundinaria alpina), in Bore District, Southern Ethiopia
Authors: Emire Aschalew , Demise Sintayo , Giri Temesgen
Published: November 2024

Bamboo is widely recognized as a highly renewable, fast-growing, economic raw material. Moreover, bamboo has the capability of mitigating climate change as it restores degraded land , act as carbon sequesters and protects from soil erosion. The study evaluated the effects of provenance variation on growth performance of indigenous highland bamboo species (Arundinaria alpina) in Bore District, Southern Ethiopia. Three provenances of indigenous highland bamboo species (Arundinaria alpina) such as Dimtu Hambela, Injibara and Shanan were collected from different parts of the country. Those collected provenances were planted in Bore Agricultural Research Center, on station in a Randomized Complete Block Design in three replications. Dimtu Hambela provenance had higher survival rate (85.1%) followed by Shanan (65.6%) and Injibara (64.8%) provenances. The maximum number of new emerged shoots (21.3) and number of nodes (29.9) were recorded in Dimtu Hambela provenance. In terms of root collar diameter and diameter at breast height, Dimtu Hambela provenance had (3.01cm) and (3.56cm) respectively. However, root collar diameter (2.23cm) and (2.12cm) and diameter at breast height (1.72cm) and (2.36cm) were recorded from Injibara and Shanan provenances respectively. Moreover, the highest internode length (32cm) and culm height growth (5.7cm) was recorded from Dimtu Hambela provenance followed by Shanan and Injibara provenances. Therefore, based on their growth performances Dimtu Hambela and Shanan provenances of indigenous highland bamboo species (Arundinaria alpina) were recommended and they could be demonstrated and popularized around Bore district and in similar climatic condition. Furthermore, vegetative propagation study of the recommended provenances should be mandatory in order to expand the indigenous highland bamboo resources.
Grade 10 Students’ Experiences with Catch-Up Fridays
Authors: Saro Jeffry M. , Hunt Jovelyn C. , Dequia Francis Rex M. , Mancera Joliemar C.
Published: November 2024

This study investigated Grade 10 students’ experiences with Catch-Up Fridays at Prosperidad National High School during the 2023-2024 academic year. Utilizing a phenomenological approach, the research aimed to understand how students engaged with the program and its impact on their reading proficiency. A total of 30 Grade 10 students from Prosperidad National High School in Prosperidad District I, Agusan del Sur, were selected through purposive sampling for in-depth interviews. The study employed thematic analysis following Braun and Clarke’s (2006) guidelines, beginning with detailed readings of interview and focus group discussion transcripts. The findings revealed both challenges and benefits associated with the Catch-Up Fridays program. Students encountered significant issues with time management and task overload, which led to stress and decreased academic focus. The lack of engagement and relevance in some activities further diminished motivation, while limited teacher support exacerbated these difficulties. However, the program also demonstrated notable benefits, such as improved reading skills, increased engagement with diverse texts, and enhanced motivation and attitudes toward reading. These outcomes were consistent with the Theory of Student-Driven Learning, which emphasized the importance of student autonomy, relevant learning activities, robust support systems, and peer collaboration. The study highlighted the need for balancing workload, tailoring activities to student needs, ensuring effective support, and fostering a collaborative learning environment to improve the effectiveness of Catch-Up Fridays. Future research should explore integrating structured peer collaboration to enhance the program’s impact on student learning and confidence.
Strategies for Supporting Teacher’s Professional Development and Retention in Parayao Centro Elementary School
Authors: Galeng Rovelyn R.
Published: November 2024

This study investigates effective strategies to support teachers’ professional development and retention in a mid-career teaching staff sample. It explores demographics, educational qualifications, and professional development preferences, highlighting teachers’ challenges. The sample consists of 60% aged 35-44, with 50% having 11-20 years of teaching experience, and is predominantly female (90%), with half holding a Bachelor’s degree and 40% possessing a Master’s degree. Despite high engagement in professional development activities such as reskilling, cross-skilling, and upskilling, significant barriers remain, including time constraints and program costs. The findings reveal a preference for collaborative learning, mentoring, and in-person workshops, while independent study and online courses are less favored. These insights emphasize the need for practical, interactive professional growth opportunities that align with teachers’ learning styles. Educational institutions and policymakers must address the time and cost barriers, offering flexible and accessible development programs that cater to teachers’ preferences. Recommendations focus on fostering reskilling and cross-skilling through interactive, collaborative formats, minimizing common barriers to enhance the professional development experience. By accommodating teachers’ preferred learning styles and minimizing obstacles, educational institutions can contribute to improved teacher retention and overall effectiveness in the classroom. This study provides actionable insights for developing teacher-focused professional development strategies that align with their career stages and preferences, ultimately contributing to more effective retention efforts and fostering long-term success in educational settings.
Comparative Antibody Responses of Four Turkey Strains to Attenuated Salmonella Vaccine: A Path to Enhanced Poultry Production
Authors: Efienokwu Jude Ngozichukwuka , Ekerette Ekerette Emmanuel
Published: November 2024

The increasing demand for turkey as a protein source necessitates effective management practices, particularly in combating Salmonella infections. This study evaluated the immune response of four turkey strains (black, white, exotic, and lavender) to a Salmonella gallinarum-9R strain vaccine. A total of 180 samples of day-old poults (45 from each strain) were used for the experiment. Following initial blood sampling at four weeks, all birds were vaccinated orally with the Salmonella vaccine. Monthly blood samples were collected over four months to assess antibody titres using a serial dilution method. Results revealed significant differences in the mean antibody responses among the strains. The black strain exhibited the highest mean antibody titre (1.38), followed closely by the exotic (1.32) and white (1.30) strains, while the lavender strain showed the lowest titre (1.17). The antibody titres significantly increased post-vaccination compared to pre-vaccination values (p < 0.05). These findings highlight the effectiveness of vaccination in enhancing immunity in turkeys, suggesting that selective breeding of more responsive strains could improve flock health and reduce the risk of Salmonella infection.
Orally disintegrating tablets: formulation, preparation, and quality control assessment
Authors: Mohamed Asmaa
Published: November 2024

Orally disintegrating tablets (ODTs) are a new formulation that dissolves in saliva within seconds, and there is no need to drink water. Due to its many benefits, this dosage form is an effective way to administer active pharmacological substances, especially for pediatric, geriatric, psychiatric, paralyzed, and bedridden patients. ODTs have been shown to have superior patient compatibility and drug solubility in numerous studies that have compared this tablet form with conventional forms in vitro and in vivo. There are many substances used to achieve enhanced characteristics, including super disintegrants such as croscarmellose sodium and crospovidone to achieve rapid disintegration and dissolution, and selection of appropriate diluent, binder, sweetening agents, flavoring materials, and lubricant are required to make tablets dissolve quickly. This dosage type can be prepared in several techniques, including direct compression, sublimation, freeze-drying, lyophilization, spray drying, molding, Process of cotton candy, Massextrusion, phase extrusion, and Melt Granulation. Formulation and selection of appropriate excipients are discussed, and ODTs' preparation techniques are illustrated in this review. Laboratory evaluation and quality control measures, including precompression (micromeritics parameters) to adjust formulation and obtain the optimized formulations to be produced and scale up and post-compression parameters for ODTs, are also discussed in this review.
Correlation of LaboratoryParameters Between Subgroups of "Wild Type", Mutated, Heterozygous Patients Based on the Presence of Rs231775 CTLA-4 Gene Polymorphisms in Pluriglandular Autoimmune Syndrome (PAS III)
Authors: Beslic Vanja , Burekovic Azra , Bostandzic Amela , Balic Sefkija , Surkovic Ismana
Published: November 2024

Background: Autoimmune thyroid disease and diabetes mellitus type 1 are multifactorial diseases, in which there are several common, suspect genes, as well as environmental factors that contribute to the etiology of the disease. These genes were nominated as common susceptibility genes for PAS-III. Family and population studies have shown that PAS IIIA has a strong genetic background. Objective: In this work, gene polymorphisms were examined in 50 patients with PAS-IIIA. It is about polymorphism CTLA-4 gene polymorphism: rs231775. Rs231775, also known as + 49 A/G (or CTLA-4 A49G), is a common nonsynonymous CTLA-4 polymorphism. So far, it has been linked to several autoimmune diseases, especially autoimmune thyroiditis, as well as several other disorders. Methods: Peripheral blood of 50 patients was used as clinical material for the study. DNA was isolated from the collected peripheral blood samples using the Qiamp DNA mini kit, using the attached protocol and manufacturer's instructions. We also performed laboratory blood tests: Hba1c values as a parameter of glycoregulation in the last 3 months, fasting and 2-hour glycemia values, total cholesterol and triglyceride values, anti-TPO and anti-Tg thyroid antibodies. We were interested in the difference in laboratory tests in subgroups GWT, GM and GH. Results: Using the chi-square test, the association between the rs231775 polymorphism and PAS-III was proven. The values of GUK, HbA1C, cholesterol, triglycerides, antibodies to thyroglobulin and antibodies to thyroperoxidase were not statistically significantly different in all three subgroups of patients suffering from PAS III. Conclusion: It has been previously shown that people with a mutation in one allele of CTLA-4 are highly susceptible to autoimmunity, which raises the possibility that more subtle variations in the level of CTLA-4 in the general population can influence the response to therapy. Non-pathogenic polymorphisms in CTLA-4 that alter CTLA-4 expression may affect an individual's lifetime risk for the development of autoimmune and malignant disorders..
Visually guided actions of urban traffic users
Authors:   , Chiozi Gotardi Gisele
Published: November 2024

This thesis investigates visually guided actions of urban traffic users, specifically drivers and cyclists, through different theoretical frameworks. It is divided into two parts, each employing distinct guides to discovery.
Part 1: The focus is on drivers' gaze behaviour during virtual navigation grounded in cognitivist approaches. Three experiments investigate the relationship between visual attention and driving performance among vulnerable driver groups. Study 1 explores the impact of anxiety on attention and performance in driving, revealing that while anxiety impairs processing efficiency and performance effectiveness for both inexperienced and experienced drivers, it shows that attentional shifts differ based on experience level. Study 2 investigates how race gaming experience influences gaze behaviour and driving performance, showing that drivers with gaming experience allocate more attention to task-relevant source of information, highlighting how virtual experience can be used as good training for enhancing gaze behaviour and driving performance. Study 3 examines gaze behaviour and driving performance among drivers with Parkinson's disease (PD) and healthy older and younger adults, finding that PD affects performance and gaze behaviour negatively. PD drivers had more collisions and spent less time within the speed zone. Their gaze behaviour was more random, with increased fixations on irrelevant areas and higher visual entropy. Older drivers concentrated their visual search on the lane to detect threats.
Part 2: I shift my guide to discovery to the ecological concept of affordances, investigating the role of perceiving affordances in movement control. Study 4 investigates whether the visual control of braking in cycling is affordance-based. Maximum achievable deceleration was manipulated by adding weights to the bike, and two approach distances are used to vary speed. Participants increased brake adjustments as they approached the action boundary, indicating an affordance-based control strategy. Active cyclists predominantly used the aggressive style, suggesting experience influences braking strategies. Finally, Study 5 explores action scaling in braking relative to preferred and maximum deceleration in cycling on different terrain slopes. Participants began braking earlier with lower deceleration on the downhill slope. Aggressive braking style was more prevalent during the uphill than the downhill slope. Both styles adjust braking magnitude as deceleration increases, supporting the affordance-based approach.
In summary, this thesis advances our understanding of visually guided actions in urban traffic through the study of different theoretical frameworks. Due to its greater ecological representativity and more parsimonious explanation, the affordance-based control approach emerges as the most appropriate perspective for investigating visual perception-action coupling in traffic navigation.
Implications of Wet Leasing to Paper Airlines: Generating Capacity Outside an Air Service Agreement
Authors: Haffey Connor
Published: November 2024

Operating aircraft under leasing has increased greatly over the past twenty years. One type of aircraft leasing, wet leasing, is the practice of providing not only the aircraft to the lessee but also at least some of the crew, and potentially the maintenance, and insurance for the aircraft. In a wet lease agreement, because the lessor usually provides the majority of the aircraft’s servicing functions, the lessor is typically considered the operator of the aircraft but the aircraft is flown under the lessee’s designator code. In states where substantial ownership regulations are less restricted, an airline in one state can own a paper airline in another state. In such a scenario, the lessor may own the foreign airline that it wet leases to and use the lessee’s traffic rights.This paper focuses on the implications of a lessor wet leasing to a foreign paper airline in which the lessor has a financial stake. One such implication includes how the lessor can use the lessee’s traffic rights to generate a route between the lessor airline’s state of registry and a third state without an air service agreement between the states. The primary, and seemingly only, example of this innovation is the TACA airlines arrangement with LACSA that created a route between El Salvador and Canada from 2006 to 2010, when El Salvador and Canada did not have an air service agreement. Other implications of similarly innovative wet leasing arrangements to a paper airline or struggling airline are also analysed, such as an expansion of capacities beyond that provided in an air services agreement (ASA).
The Legal Regime of the Areas Beyond National Jurisdiction in the BBNJ Agreement and Lessons Learned for Space Law
Authors: Eryavuz Feriha Beyza , Burger Merve Erdem
Published: November 2024

As a result of the discussions on ocean pollution in recent years, the ‘Agreement under the United Nations Convention on the Law of the Sea on the Conservation and Sustainable Use of Marine Biological Diversity of Areas Beyond National Jurisdiction’ (also known as the BBNJ Agreement) was signed on 4 March 2023. One of the most notable aspects of the Agreement in question is that it imposes certain responsibilities on states in a region that are not subject to the sovereignty of any state, while states may extend their jurisdictional authority to these regions only in the case of certain exceptions such as registration.This development can serve as a significant illustrative record of the interaction between environmental protection and state accountability in places like Antarctica or outer space, which are also not under state jurisdiction. This study addresses the lessons learned from the BBNJ Agreement for the environmental protection of outer space by examining benefit-sharing mechanisms, area management tools, and environmental impact assessment in the BBNJ Agreement and makes suggestions on how to strengthen the protection of the space environment through these mechanisms.
Protection of Children's Rights to Obtain Quality Education in the Era of Elementary School Zoning System Policy in Semarang City
Authors: Ardiansyah Rico , . Kunarto
Published: November 2024

The research objective in this writing is to determine the implementation of Minister of Education and Culture Regulation Number 1 of 2021 on the process of accepting new students using the zoning system in Semarang City; to find out the process of fulfilling children's rights to educational justice in the zoning system in Semarang City and to find out the factors that become obstacles in the implementation of the school zoning system. This research uses empirical juridical methods with a descriptive analytical approach. The data sources in this research use primary data and secondary data. Data collection methods were carried out by interviews, observation and document study. Education is a human right so it has an important role in social life. The aim of implementing education is to educate and develop the morals of the nation so that it becomes better and more dignified. The right to education is a human right for every individual so that every individual has the right to obtain higher education. The results of this research show that the implementation of the New Student Admission (PPDB) zoning system at SD Negeri Srondol Wetan 06 Semarang, SD Negeri Srondol Wetan 04 Semarang and SD Negeri Srondol Wetan 02 Semarang have implemented the Implementation of New Student Admission (PPDB) zoning system in accordance with the Ministry of Education and Culture Regulation (Permendikbud) Number 1 of 2021 and Semarang Mayor Regulation Number 25 of 2023.
Sustainability and Operational Efficiency in Air Cargo: Insights from Turkish Cargo's Management Practices
Authors: Macit Armağan
Published: November 2024

This study examines the concepts of sustainability management and efficiency in air cargo companies. In particular, the impacts of sustainability-focused activities carried out by Turkish Cargo between 2018 and 2023 on operational efficiency were evaluated. Based on THY Inc.’s sustainability reports, we conducted a qualitative analysis by evaluating and interpreting Turkish Cargo’s sustainability management and efficiency-focused initiatives. By extracting cargo data from the general reports published by THY Inc. between 2018 and 2023 and Turkish Cargo’s sustainable management policies, we determined that the company primarily focuses on sustainable growth, environmental sustainability, social sustainability, and efficiency. We also found that Turkish Cargo aims to achieve efficiency through digitalization and fleet management during this period. This study addresses a gap in existing research by focusing on the evaluation of sustainability management and efficiency concepts in air cargo transportation. Our analysis of Turkish Cargo provides a unique example at both the sectoral and organizational levels by revealing the tangible results of sustainability management. Offering a new perspective on the integration of sustainability management with efficiency, this study contributes to the literature at both theoretical and practical levels.
Applications and Future Perspectives of Swarm Intelligence in Unmanned and Autonomous Systems
Authors: Yazıcı Ayşe Meriç , Akdemir Ömür Gökçe , Askun Celik Duysal
Published: November 2024

This paper examines the potential implications of the principles of swarm intelligence and collective behavior in nature for unmanned systems and autonomous organizational structures. Swarm intelligence is inspired by natural systems in which individual units interact according to simple rules to form a complex and organized whole. These principles can be observed in a wide range of situations, from the synchronized flight of flocks of birds to the harmonized swimming behavior of schools of fish. The study emphasizes that swarm intelligence principles have the potential to create more flexible, resilient and efficient systems with decentralized control mechanisms and autonomous decision-making processes. Furthermore, it is suggested that these approaches can find applications in many fields, from military operations to agricultural and environmental monitoring, from disaster response to urban planning. The study provides a detailed analysis of swarm behavior in nature and discusses how these behaviors can be emulated and optimized in unmanned systems. In this context, the potential impacts of swarm intelligence and collective behavior principles on unmanned systems are evaluated in terms of increasing their adaptability, optimizing energy efficiency and maximizing mission success. It is also argued that these principles can contribute to making unmanned systems more resilient to contingencies and changing environmental conditions. Swarm intelligence principles can be used to provide more effective coordination in unmanned air, land and sea vehicles. In digitalizing sectors, the flexibility of businesses can be increased and resource usage can be optimized by creating decentralized decision-making mechanisms.
Design of Miniaturized Ion-Selective Electrodes and Practical Applications
Authors: Březnová Hana , Broncová Gabriela , Shishkanova Tatiana V.
Published: November 2024

Miniaturized membrane ion-selective electrodes are introduced. The body of electrode is made of a poly(vinyl chloride) tube with an internal porous frit, which is a mechanical support for the membrane. The membrane is created by a one-time or repeated dipping of the electrode tip into the membrane cocktail dissolved in tetrahydrofuran (THF). The thickness of the membrane is controlled by the number of dipping and/or the viscosity of the membrane cocktail, or the amount of THF. The electrodes were characterized in term of repeatability, dynamic response properties, working ranges, and sensitivity. Their analytical performance was compared with literature data for conventional membrane ion-selective electrodes. This electrode design can be a simple alternative to classical/traditional membrane electrodes for various analytical applications.
Voltammetric Determination of the Drug Metronidazole Using a Solid Bismuth Drop Electrode
Authors: Jarošová Johanka , Vyskočil Vlastimil
Published: November 2024

Solid bismuth drop electrode (SBiDE) is a new working electrode commercially available on the Czech market since 2020 by the company Metrohm. The aim of this work was to verify the applicability of SBiDE for the voltammetric determination of a model organic substance representing electrochemically reducible biologically active compounds, namely, the drug metronidazole (an antibiotic used to treat diseases caused by both Gram-positive and Gram-negative anaerobic bacteria). To the best of our knowledge, this is the very first published research work using SBiDE. Under optimum conditions (Britton-Robinson buffer of pH 12.0 was used as the supporting electrolyte and the working electrode surface was not electrochemically regenerated), a linear calibration dependence of metronidazole was obtained using differential pulse voltammetry (DPV) in the concentration range from 1 to 600 μmol L–1, with the limits of detection (LOD) and quantification (LOQ) of 0.41 μmol L–1 and 1.4 μmol L–1, respectively. Cyclic voltammetry (CV) on SBiDE was used to characterize the electrode process of the irreversible reduction of metronidazole. The newly developed DPV method was also successfully applied for the determination of metronidazole in authentic drinking water samples (LOD = 1.8 μmol L−1 and LOQ = 5.8 μmol L−1) and in various dosage forms (UV-Vis spectrophotometry was used as a comparative analytical method).
Full text English translation is available in the on-line version.
Flora of Guaramacal(Venezuela) II: Gymnosperms, Angiosperms(Chloranthales, Magnoliids)
Authors: Dorr Laurence J. , Niño S. Miguel
Published: November 2024

The present volume is a taxonomic study of the Gymnosperms and Angiosperms (Chloranthales and Magnoliids) that occur in Guaramacal National Park(officially Parque Nacional “General Cruz Carrillo en Guaramacal”), which protects the Ramal de Guaramacal, an outlier of the more extensive Cordillera de Mérida in the Venezuelan Andes. The park covers 215 km2 in Trujillo and Portuguesa states and includes cloud forest and páramo found between 1,600 and 3,150 m elevation. In all, nine families, 23 genera, and 97 species are treated; the greatest species diversity occurs in Piperaceae (50 species), Lauraceae (31 species), and Chloranthaceae (7 species). The most species-rich genera treated in this volume are Peperomia (31 species), Piper (18 species), and Ocotea (12 species). Five species treated here were described from collections made in the park and are currently known only from Guaramacal. One new combination, Piper morii (Steyerm.) Dorr & S. M. Niño, is made.
Кластерне управління проєктами: підходи, виклики та перспективи
Authors: Старченко Г. В.
Published: November 2024

The article examines cluster project management as a modern innovative approach to organizing and coordinating projects. It establishes that cluster management is based on the consolidation of interrelated projects into clusters for the joint use of resources, enhancing the efficiency of innovative potential utilization, and stimulating innovation. Cluster management allows for resource optimization, improved communication, the development of synergy between projects, and decision-making flexibility. The article analyzes the main types of clusters, including geographical, sectoral, vertical, and horizontal, and their impact on the success of project management and the productivity of individual projects. It also discusses the key advantages of cluster management, including resource optimization, improved coordination among participants, increased overall productivity, and flexibility. The study reveals that the cluster approach helps reduce costs, avoid duplication of efforts, promotes rapid market response, and allows organizations to effectively adapt to market challenges. In addition to the advantages, the article highlights the challenges organizations face when applying the cluster approach. These include the need to adapt to external changes, competition among cluster participants, and intellectual property protection, which can pose a threat to innovation. A new approach to cluster project management is proposed, which integrates vertical and horizontal clusters with modern digital technologies, such as monitoring and management tools. This approach enhances the effectiveness, resilience, and innovativeness of projects in the context of globalization and digitalization. The article also explores successful examples of clusters, such as the Silicon Valley technology cluster and the California wine cluster, which illustrate the benefits of collaboration within a cluster system. The article emphasizes the importance of flexibility and continuous updating of management methodologies to ensure the success of clusters in today's competitive environment.