bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular investigation of effects of probiotic on papG and iutA genes in different strains of E.coli isolated from urinary tract infection
Authors: Romina Rezaei , Mona Mohammad Aliha , Roudabeh  Behzadi Andouhjerdi , Maryam Tajabadi Ebrahimi
Published: October 2023

Escherichia coli-induced urinary tract infections (E.coli-UTIs) are considered one of the most prevalent infections in Iran. One of the important factors of pathogenicity, particularly in its binding to epithelial cells, is the presence of iutA and papG virulence genes in Escherichia coli (E.coli). Lactobacilli, as a group of probiotics, play a vital role in the body and are useful in some cases due to their therapeutic effects. The aim of this study was to evaluate how the molecular activity of Lactobacillus casei PTCC1608 influences different strains of pathogenic E.coli isolated from urinary infections through PCR. In this study, the pathogenic strain of E.coli was isolated from the patients with Urinary Tract Infections (UTIs) and analyzed by the use of the PCR method. Then, the strains with positive genotypes were isolated and the antimicrobial effect of Lactobacillus casei was evaluated through the disc diffusion and dilution methods in liquid medium. The antimicrobial effect of Lactobacillus casei on E.coli bacteria isolated from urine samples from 40 patients with UTI was studied. In addition, the results of the antibiotic sensitivity test at 1:10 dilution showed a growth inhibition zone of 9 mm. The results indicated that the isolated bacterium was not resistant to the ampicillin and the antibiotic treatment was effective for this strain. Moreover, the probiotic also plays a therapeutic role and can improve urinary infections.
Physicochemical characterization and biological activity of polysaccharides from the seeds of the turnip brassica rapa
Authors: Yuliya I Oshchepkova , Мunojat J Oripova , Zulfizar N Kuzieva , Barno B Koraboeva , Dilnoza G Abdugafurova , Dilfuza Amanlikova , Shavkat I Salikhov
Published: October 2023

Analysis of the monosaccharide composition showed that the composition of the neutral polysaccharide BSP-1-1 is represented by monosaccharides in the following composition: ribose – 5.05%, arabinose – 56.38%, mannose – 5.87%, glucose – 8.63% and galactose – 24.05%. The composition of the anionic polysaccharide BSP-2-1 is represented by monosaccharides: ribose – 6.35%, arabinose – 60.15%, mannose – 7.19%, glucose – 4.12% and galactose – 22.16%. It was determined that the isolated polysaccharides consist mainly of arabinose (BSP-1-1 – 56.3%, BSP-2-1 – 60%) and galactose (BSP-1-1 – 24%, BSP-2-1 – 22%). Based on the data obtained, it can be assumed that the studied polysaccharides from the seeds of the turnip Brassica rapa belong to the type of arabinogalactans. According to the results of studying the properties of acute toxicity of the BSP polysaccharide from the seeds of the turnip Brassica rapa, it was found that this substance belongs to class V compounds - practically non-toxic substances. With intragastric administration of inulin at doses of 25, 50, and 75 mg/kg and BSP polysaccharide from the seeds of the turnip Brassica rapa at doses of 10, 20 and 30 mg/kg 14 days after the induction of diabetes mellitus, the indicator was close to that of the intact group of animals (intact - 3.07 ± 0.25, inulin 2.99 - 3.14 ± 0.23, and BSP polysaccharide from the seeds of the turnip Brassica rapa 2.53-3.14 ± 0.20), while the indicator of the control group was - 8.40 ± 0.35. This study will provide an opportunity to plan and conduct studies to study the action of substances in the metabolism of glucose and lipids, which examines the enzymes that regulate the lipid activity of the liver, as well as the morphology of the liver and adipose tissue.
Visualization of the obscure inhalation stage in inhalation therapy
Authors: Hiroyuki Ohbayashi
Published: October 2023

The flow of the inhalation procedure during inhalation therapy can be divided into three successive stages: a pre-inhalation preparatory stage, a drug inhalation stage, and a post-inhalation stage. Among these, the second stage, drug inhalation, is the most important and obscure. Using ambiguous verbal expression, the drug inhalation method is communicated to the patient using terms such as strongly, deeply, and slowly. Patients usually determine their optimal method of drug inhalation device independently, based on their own interpretation and understanding of the verbal instructions. This may make the precise inhalation using an inhalation device unpredictable. The Tokico Inhalation Monitor TM (TIM) was developed to resolve the unpredictability of this second (drug inhalation) stage. The TIM can simultaneously measure the inhalation flow rate, duration, and total volume, and display them on the screen in real-time. This mini-review demonstrates the effects of inhalation instruction using TIM, which allows the second stage of therapy, drug inhalation, to be displayed on a screen in real-time.
Thyroid profile prognostic value on disease severity and mortality in COVID-19
Authors: Naglaa M Farag , Nehal I Abbas , Mahmoud Mousa , Ragaa Matta , Alyaa E , Samar Mansour
Published: October 2023

Background: Precise accurate triage of Coronavirus disease 2019 (COVID-19) patients during hospitalization for early identification of individuals at risk of developing severe disease is essential as Intensive Care Units (ICUs) are overwhelmed by the pandemic burden. The aim of this study was to evaluate thyroid function in patients with COVID-19. Methods: 60 healthy controls and 180 patients were admitted to a cardiothoracic hospital, Minia University, Egypt, between March 2020 and September 2021 without a history of thyroid disease. Patients divided as 60 non-COVID pneumonia patients with a similar degree of severity were included as another control group to find any unique effects of COVID-19 on thyroid function, 120 positive COVID-19 divided according to clinical classifications into moderate (n = 58), severe (n = 21), and critical (n = 41), Critical group were admitted to ICU and classified to survivors (n = 33) and non-survivors (n = 8). COVID patients also were divided into tertiles according to their FT3 levels. Lowes tertile (n = 45), middle tertile (n = 37) and highest tertile (n = 38). All participants underwent routine physical checkups, acute physiology, and chronic health evaluation (APACHE-II) scores. The outcome measure was death during hospitalization; intensive care admission, mechanical ventilation, and length of hospitalization. We analyzed the ability of each parameter to predict mortality in participants. Further, we also evaluated whether the combination of free triiodothyronine (FT3) level with APACHE-II score could improve the mortality prediction. Results: Thyroid Stimulating Hormone (TSH) was lower than normal range in 56.7% (68/120) of patients with COVID-19. TSH and serum-free triiodothyronine (FT3) were significantly lower in COVID-19 patients than healthy control and non-COVID-19 pneumonia patients. TSH and FT3 were lower in severe COVID-19 with statistical significance (p < 0.001) and both positively correlated with the severity. The free thyroxine (FT4) in COVID-19 patients was not significantly different from the control group. Patients in the lowest FT3 tertile had significantly higher rates of mortality (18/40), mechanical ventilation (24/53.3), and intensive care unit admission (20/44.4). In univariate analyses, FT3 remained the most significant independent predictor of death. Conclusion: The changes in serum TSH and FT3 levels may be important manifestations of COVID-19 courses.FT3 levels can serve as a prognostic tool for disease severity in early presentation of COVID-19.
hsqc_metab.nan v1
Authors: KB NAN , Glushka John , Uchimiya Mario , Al Jawad Saraa , Esselman Christopher , I Ponce Leandro , Morris Laura , Edison Arthur
Published: October 2023

This is a protocol for running the Bruker pulse program "hsqcetgpsisp2".
DengueSeq: A pan-serotype whole genome amplicon sequencing protocol for dengue virus v2
Authors: Vogels Chantal
Published: October 2023

Version 3 updates: Updated abstract Included link to preprint and bioinformatics pipeline Added links to additional library prep kits Included DENV2 and DENV4 sylvatic reference genomes and BED files Changed primer names in BED files DengueSeq preprint: https://www.medrxiv.org/content/10.1101/2023.10.13.23296997v1 Bioinformatics pipeline: https://github.com/grubaughlab/DENV_pipeline/tree/v1.0 Background The increasing burden of dengue virus on public health due to more explosive and frequent outbreaks highlights the need for improved surveillance and control. Genomic surveillance of dengue virus not only provides important insights into the emergence and spread of genetically diverse serotypes and genotypes, but it is also critical to monitor the effectiveness of newly implemented control strategies. Here, we present DengueSeq, an amplicon sequencing protocol, which enables whole-genome sequencing of all four dengue virus serotypes. Results We developed primer schemes for the four dengue virus serotypes, which can be combined into a pan-serotype approach. We validated both approaches using genetically diverse virus stocks and clinical specimens that contained a range of virus copies. High genome coverage (>95%) was achieved for all genotypes, except DENV2 (genotype VI) and DENV 4 (genotype IV) sylvatics, with similar performance of the serotype-specific and pan-serotype approaches. The limit of detection to reach 70% coverage was 10-100 RNA copies/μL for all four serotypes, which is similar to other commonly used primer schemes. DengueSeq facilitates the sequencing of samples without known serotypes, allows the detection of multiple serotypes in the same sample, and can be used with a variety of library prep kits and sequencing instruments. Conclusions DengueSeq was systematically evaluated with virus stocks and clinical specimens spanning the genetic diversity within each of the four dengue virus serotypes. The primer schemes can be plugged into existing amplicon sequencing workflows to facilitate the global need for expanded dengue virus genomic surveillance. Link to DengueSeq preprint.
Immunohistochemistry on free-floating cryosections v1
Authors: not provided Nuriapenuelas
Published: October 2023

Immunochemistry protocol on rodent brain cryosections
Bulk RNASeq Delivery v2
Authors: Stahl Tyler
Published: October 2023

This protocol will give an overview of the grc data delivery structure and results files
Digital Engraving Digital Art Design Analysis Based on Spatial Expression Techniques
Authors: Chu Zichen , Han Bo
Published: October 2023

Aiming at the problems of poor transmission effect and serious data loss in digital engraving, this paper puts forward a digital modeling model from the perspective of spatial expression. First, in-depth analysis of the original digital art design can not solve the problem of digital carving accuracy, and analysis of the reasons for the poor calculation accuracy of digital carving. Using wireless network technology and WIFI technology to obtain digital information of digital engraving, through the Internet design scheme statistics, according to the digital features to judge the form and result of engraving, remove irrelevant spatial information. Then, according to the Internet data monitoring, the change rate and engraving method of the engraving data are calculated, and compared with the actual engraving requirements, the parameters and indicators of digital art design are adjusted. MATLAB simulation test analysis shows that in the case of wireless communication and Internet monitoring, the digital engraving model of spatial expression technique can improve the accuracy of artistic design, and the accuracy rate is greater than the actual design requirements. According to the design requirements of different wireless networks and network communications, the time and compliance rate of digital engraving can meet the needs of artistic design.
Prevalence and Incidence of Type-2 Diabetes Mellitus Among the Rural Population of Erode District of Tamil Nadu, South India
Authors: Theivasigamani Kumutha , Palaniappan Senthilkumar
Published: October 2023

Diabetes mellitus is a group of metabolic disorders characterised by hyperglycaemia, caused by elevation of blood glucose level. A sedentary lifestyle is the most common cause of diabetes and has a wide range of long-term effects, including cardiovascular disease, kidney disease, blindness, and disability. Over the last two decades, diabetes has become more widespread in low and middle-income countries than in high-income countries. The study was aimed to determine the prevalence and incidence of type 2 diabetes mellitus among the rural population of Erode district, Tamil Nadu, India. A cross-sectional study was conducted for a period of one year. Data was collected from 870 individuals using a predesigned structured questionnaire covering the individual’s demographics, History of DM, finding, lab variables, comorbidities, problems of DM, and therapy provided. Most of the diabetic individuals were females (n= 493; 56.66%), Married (n=824; 94.71%), Un employed (n= 208; 49.06%) and Illiterate (n=238; 27.35%). Most of them aged between 56-65 years (272; 31.26%), having Past Medical History of Type-II DM (n=255; 29.31%), High blood pressure (n=486; 55.86%), and hyperlipidaemia (n=20; 2.29%). Most of the respondents were having the co morbidities of diabetes mellitus with high blood pressure (n=483; (55.51%), followed by diabetes mellitus alone 258(n= 29.65), All the individuals in this present study were diagnosed with type-2 diabetes mellitus (n=487; 100%), taking oral hypoglycaemic agents (n=755; 86.78%), 108 (12.41%) patients were treated with insulin plus Oral Hypoglycaemic agents, whereas only 7 (0.80%) patients were treated with insulin alone. Women are more likely to have diabetes, and married, obese, and overweight people are more likely to have it. Metformin was the most often used single drug therapy to treat DM, and OHA was the recommended option for antidiabetic medication. The incidence and prevalence of diabetes among this demographic increased as a result of incorrect way of living and an absence of knowledge about dm and its effects. This is a critical health issues, and it may raise the morbidity and death if not resolved right way. A well-structured health comprehensive programme must be executed in order to decrease detrimental health results and enhance quality of life for the research population.
Russian–African cooperation and summit diplomacy. Challenges and opportunities
Authors: Fedorchenko A. , Krylov A. , Morozov V. , Shebalina E. , Loshkarev I.
Published: October 2023

The article examines the perspectives of summit diplomacy in relations between Russia and the countries of the African region. Summit diplomacy in the context of this article can be considered as an integral part of multi-vector network diplomacy, which is an effective addition, and sometimes an alternative to traditional diplomacy, despite the fact that officials also take part in the summits. The authors note that in studies on the diplomacy of summits, insufficient attention is paid to the substantive aspects of the relations between their participants. Thus, the summits imply consideration of a wide range of tasks, including those of a domestic political nature. At the same time, as an instrument of foreign policy, the effectiveness of summit diplomacy depends not only on the structural characteristics of relations, but also on the dynamics of interaction between the participants. The countries of the African region have rich mineral deposits, vast areas that could potentially be suitable for highly productive agriculture; forests, including the most valuable species of trees, as well as a huge population, which can become the basis for one of the world's largest markets for goods and services. It is African countries that occupy the first places in terms of GDP growth prospects and the rapidly growing economy as a whole. Transnational corporations have long been fighting for control over resources, access to cheap labor and the population's money, increasing their presence on the continent. In this regard, Africa has become the object of special attention of leading international players, including Russia. Thus, at present, a certain return of Russia's real interest in Africa is being ascertained. In the first part of the article, the authors analyze the economic opportunities of Russia and its main interests in relations with the countries of the African region. The second part deals with the development of Africa and the negotiating agenda of African states. The third part deals with new points of growth and promising areas of interaction between Russia and Africa.
Inflation in the context of geopolitics in France and the eurozone
Authors: Klinova M. , Sidorova E.
Published: October 2023

The article seeks to examine the relationship between the current surge in inflation in the eurozone in general and in France in particular, the economic growth problems and the resulting erosion of the population purchasing power. It was found that the surge in inflation began even before the geopolitical tensions of early 2022 and was associated with large-scale packages of State assistance to the population and businesses to combat the economic downturn caused by the outbreak of COVID-19. The rise in inflation at the end of 2021 was linked to monetary factors, and inflation in 2022 became a more complex phenomenon when its acceleration began to acquire a mixed monetary and non-monetary character. This is due to geopolitical transformations that have led to an increase in prices for energy and other raw materials. It is shown that inflation undermines economic growth prospects and erodes household purchasing power. It is concluded that the anti-inflationary monetary policy of the European Central Bank will affect the inflation rate. Yet, at the same time, economic growth will also slow down in the medium term. Not only France, but also other eurozone countries as a whole are interested in stimulating it. Simultaneously, the situation regarding income and purchasing power will display positive, but insignificant dynamics. The article evaluates measures aimed at propping up purchasing power in France as one of the leading countries of the European Union. The French State possesses and employs a wide range of opportunities to underpin the economy.
Minería de datos de los medios sociales: herramientas para recopilar datos de Twitter
Authors: Benítez Andrades José Alberto
Published: October 2023

En la actualidad la minería de datos de los medios sociales suele estar centrada en recopilar información procedente de Twitter. Uno de los principales problemas en el análisis de redes sociales en estos casos es la adquisición de los datos en forma de grafo. La posibilidad de hacer esta labor «a mano», es impensable cuando se tratan redes de cientos o miles de nodos en constante comunicación entre ellos. Twitter, además, es un ejemplo muy claro de esta problemática. De cualquier trending topic se pueden generan cientos de tweets en una hora. Es necesario herramientas de adquisición de todos esos datos de una forma automatizada utilizando las posibilidades que la propia red social ofrece. Un ejemplo de herramienta que ofrece una obtención de datos, con limitaciones, es la herramienta Netlytic. No es la única, pero es sencilla de utilizar. En este documento se muestra un caso de uso de un proyecto recopilado con Netlytic y graficado mediante Gephi
Psychological distress of inmates at a women’s prison in Lima after the first wave of COVID-19 in November 2020
Authors: Esteban-Febres Silvia , Guzmán-Gamarra Santos , La Cunza-Peña Melisa , Quispe-Gutiérrez Yovana
Published: October 2023

Objectives: A descriptive study was carried out to establish the levels of psychological distress amongst female inmates at a high-security prison in Lima in November 2020, after the first wave of COVID-19. Material and method: The Brief Symptoms Inventory-18 (BSI-18) was applied to a representative sample of 314 female inmates who agreed to participate in the study. Results: Results showed that 34.6% of the inmates could be considered as cases of psychological distress. Moreover, the depression subscale had the highest score, followed by the anxiety and the somatisation subscales. The most prevalent symptom was “feeling blue”. Discussion: The prevalence of distress symptoms was analyzed, taking into account the effects of the first wave of COVID-19, the suspension of family visits, the restriction of treatment and leisure activities, etc. Gender aspects were also taken into consideration.
Clinico-microbiological study of dermatophytosis in a tertiary care center and emergence of multi-drug resistant dermatophyte Trichophyton tonsurans in the sub-population of West Bengaluru, Karnataka
Authors: Samaddar Suman , Shantharaju Sanjana Agrahara , Kumaraswamy Bhargavi , Okade Rajendra , Koneri Raju , Joshua Lincy
Published: October 2023

Antifungal susceptibility is an effective technique in managing clinical dermatophytosis due to an upsurge in resistant dermatophytes.

The intention of this research was to investigate the antifungal susceptibility profile of clinically significant dermatophytes in a tertiary care setting.

A total of 330 clinical samples were isolated from patients with superficial mycoses. Macroscopic characterization was done by examining the growth period, culture topography and synthesis of pigment on the reverse. The recovered strains were identified at the species level by ribosomal DNA (rDNA) internal transcribed spacer (ITS) regions sequencing. Antifungal susceptibility and MIC (Minimum Inhibitory Concentration) were determined using the Ezy MIC Strips (Himedia) on eight antifungals viz, Griseofulvin, Amphotericin B, Fluconazole, Itraconazole, Ketoconazole, Posaconazole, Terbinafine and Voriconazole,

Out of 330 clinical isolates, 253 isolates were recovered and grown in culture, and identified by PCR sequencing. Tinea corporis was most predominant (65.15%) in the age group of 21-30 years. was the most abundant dermatophyte (47.83%), followed by30.43%) and (19.76%). Posaconazole and voriconazole exhibited highest ctivity followed by itraconazole and fluconazole. yielded highest number of antifungal-resistant isolates (89.61%), followed by (86.78%) and (76%). Posaconazole was found to be the most potent antifungal while amphotericin B was the least. emerged as an important dermatophyte with significant resistant isolates.

Analysis of our data revealed distressing existence of multi-drug resistant dermatophytes in the sub-population and also a prominent shift in the prevalence from resistant to . The emergence of a less prevalent dermatophyte in India, , was witnessed in the study population.
Coexistence of pigmentary demarcation line type B and congenital vitiligo: A unique case report and exploration of potential association
Authors: Sahoo Bijaylaxmi , Monalisa Kumari , Wadhwa Priyanka
Published: October 2023

This case report describes a rare occurrence of coexisting Pigmentary Demarcation Line (PDL) type B and congenital vitiligo in a 4-year-old girl. The patient presented with linear band of hyperpigmentation along the blaschko line on the inner sides of bilateral thighs and lower abdomen, accompanied by depigmented patches on the knees, since birth. The clinical history, examination findings, and histopathological analysis supported the diagnosis. The case sheds light on a potential association between PDL and congenital vitiligo, which is not well-documented in the existing literature. Further research and long-term follow-up are recommended to investigate the underlying mechanisms and potential genetic predisposition, providing a deeper understanding of association between these conditions.
Ephydrosis tincta - “Think Pink, but don’t wear it” – An interesting case report
Authors: Rajagopalan Rajesh
Published: October 2023

Chromhidrosis or ephydrosis tincta is a rare sweat gland disorder with a characteristic presentation of the secretion of colored sweat, first reported by Yonge in 1709. This condition can be subdivided into apocrine chromhidrosis, eccrine chromhidrosis and pseudo-eccrine chromhidrosis. Treatment depends on type and cause. Pseudochromhidrosis is the change of color of normal eccrine sweat on the skin by surface compounds, molecules or chromogenic bacteria. Here we report a case of pink coloured sweat and marked staining of clothes and under garments in a previously asymptomatic young male soft wear engineer without any underlying co morbidities that affected his quality of life. He responded well to oral antibiotics. Though unharmful, it lead to social embarrassment and psychological issues.
Unstable solar lentigo mimicking lentigo maligna melanoma: A case report
Authors: Achar Arun , Hakim Benazir , Dutta Oindrila , Sarkar Madhobendra Nath , Davis Chinjitha T , Biswas Soumi , Choudhary Smriti , Mitra Bhaskar
Published: October 2023

Solar lentigo (SL) is a hyperpigmented macule that develops due to chronic ultraviolet exposure. A 35-year-old housewife, presented with an asymptomatic pigmented patch on the right side of her nose for the last 10 years, with a rapid increase in size and variability in pigmentation over the last 3 years. She had no history of excessive sun exposure. Upon examination, there was a solitary, hyperpigmented, well to ill-defined patch of irregular shape and margin, measuring 3 cm * 2.5 cm, with variability in colour and areas of regression, almost covering Right side of nose. The patch appeared light brown with areas of dark brown and black. Differential diagnoses considered were Lentigo maligna melanoma (LMM), Solar Lentigo (SL), and flat seborrheic keratosis. Dermoscopy (Polarised illuco IDS-1100 dermoscope) revealed diffuse brown pigmentation with a faint pigmented network, along with dark brown to black globules and blotches. Due to the asymmetry of pigmentation, a punch biopsy was performed from the area of darkest pigmentation to rule out LMM. In Histology, the epidermis exhibited hyperkeratosis, follicular plugging, acanthosis, and downward elongation of the rete ridges. There was hyperpigmentation of the basal layer, an increased number of melanocytes, and the presence of melanophages in the papillary dermis. The biopsy report was consistent with Solar Lentigo (SL), and we concluded it as unstable solar lentigo (USL). This case is presented due to its clinical and dermoscopic resemblance to LMM and to increase awareness of USL and the importance of periodic surveillance.
Retrospective study of occurrence of pressure ulcers among the patients admitted in rural tertiary care hospital and their outcome
Authors: Shetti Akshaya Narayan , Chowdary Ch. Chandana , Mustilwar Rachita
Published: October 2023

This retrospective study addresses the pivotal role of pressure ulcer prevention in evaluating the quality of care within critical care units. The incidence of pressure ulcers serves as a crucial indicator, impacting patient recovery and complicating treatment.

In this data based retrospective study we assessed the prevalence of pressure ulcers for a duration of 6 years. In this data we included the patients from surgical, medical, respiratory and cardiac critical care units who were admitted between 01/06/16 to 01/06/22. All male and female patients aged above 18 years were included. Patients who got discharge within 48 hours were excluded.

Total of 35 patients were noted to have bedsores in intensive care unit from June 2016-June 2022 admitted under both medical and surgical branches. Out of which 34.3% were in age group above 70yrs where 87.9% were male patients. Most commonly 1-2 bedsores (97.1%) were present involving mostly buttock area (82.9%) of 2-5cm size (45.7%). Most of the patients admitted under medical branch developed bedsores more often than surgical branch and appeared after admission (77.1%) with 15-30 days hospital stay (31.4%).

This study has illuminated our path forward in improving patient care and preventing pressure ulcer development among patients admitted to our medical and surgical Intensive Care Units in our Rural Tertiary hospital. The findings have paved the way for targeted interventions, underlining our commitment to raising the standard of care for our critically ill patients.
Pulmonary melioidosis misdiagnosed as pulmonary tuberculosis
Authors: Sheet Chandan Kumar , Ghosh Saibal , Chatterjee Subhankar , Chandra Biplab
Published: October 2023

is a facultative Gram-negative saprophytic bacterium commonly found in soil or contaminated water causing melioidosis. Melioidosis can mimic various other disease due to its heterogenous clinical manifestations and different organ involvement. Because of its versatility it is called as “the great imitator” and remains challenging to diagnose. We report a case of melioidosis misdiagnosed and treated as pulmonary tuberculosis.

A 54-year-old male non-smoker with history of diabetes admitted with persistent cough, breathlessness and hemoptysis for 5 months. Initially there was pleuritic chest pain and high-grade fever. He was treated with multiple intravenous broad-spectrum antibiotics and anti-tubercular therapy multiple times in the local hospitals based on clinical symptoms and radiological manifestation though Sputum examination for AFB and Gene xpert for Mycobacterium tuberculosis was negative. Chest radiology showed multiple thick-walled cavities with pericavitary consolidation along with patchy infiltrative opacities. BALF culture identified . The respiratory morbidity was resolved using antibiotics based on antibiotic susceptibility tests.

This case study described a case of melioidosis in adult male with diabetes and engaged in farming presented with diverse and indistinct clinical manifestations that mimics many other diseases. Definitive diagnosis was made by isolation , in culture collected through bronchoscopic examination.
Is Energy Planning Consistent with Climate Goals? Assessing Future Emissions from Power Plants in Latin America and the Caribbean
Authors: Marinkovic Catalina , Vogt-Schilb Adrien
Published: October 2023

At least ten Latin American and Caribbean countries have pledged to achieve carbon neutrality. Has electricity planning in the region evolved towards reaching these goals? We compare power generation capacity in 2023 to announced plans in 2019. We then estimate committed emissions from existing and planned power plants that is emissions that would result from the normal operations of these plants during their typical lifetime and compare them to emissions from power generation in published IPCC scenarios. We find that fossil fuel planned capacity has decreased by 47% since 2019, mainly due to the cancellation of 50% of coal and 40% of gas projects, compared to only 32% of renewable energy projects. But existing plants in the region will emit 6.7 GtCO2 during their lifespan, and if all planned plants are built, they will add 4.9 GtCO2, totaling 11.6 GtCO2, exceeding median carbon budgets for 1.5 and 2C-consistent IPCC pathways (2.3 and 4.3 GtCO2). Natural gas power plants are the largest contributor to existing (62%) and planned (75%) emissions (versus 24% and 23% for coal). We evaluate emissions reduction strategies to achieve carbon budgets. Assuming no new coal plants comes into operation, announced gas and oil projects are canceled at the same rate as in the past four years, all fossil fueled plant lifetimes are reduced by 10 years, and all new natural gas displaces existing coal, committed emissions fall by 59%, almost meeting the 2C budget, but still twice as large as the median 1.5C budget. Our results suggest that while progress is being made, energy planning in the region is not yet consistent with global climate goals as reflected by the IPCC scenario database.
Canada's 1927 Election to the Council of the League of Nations: Imperial Unity and National Interests
Authors: Zhukovskaya Natalia
Published: October 2023

The activities of universal international organizations (the League of Nations and the UN) have always influenced the dynamics of world processes. In the article, the author examines the election of Canada to the Council of the League of Nations in 1927. This event influenced the principle of the formation of the system of electoral groups, reflected on the transformation of relations between the Empire and the Dominions, determined the vector of development of Canadian foreign policy in the framework of the concept of "middle power".
The Anxieties of Canadians in the Post-pandemic Period
Authors: Kuzmina Tatyana
Published: October 2023

The author examines the factors of concern of the Canadian population in the post-pandemic period. The analysis of the parameters of the national mood of Canadians mainly uses data for 2022 and 2023. Emotions such as anxiety, sadness, depression, disappointment, etc. are considered. The author shows how these feelings and emotions affect the overall social picture of Canadian society.
At the dawn of multiculturalism: the 50th anniversary of publishing Margaret Atwood’s “Survival”
Authors: Fedosyuk Olga
Published: October 2023

In 1972, Margaret Atwood published her book “Survival: A Thematic Guide to Canadian Literature”. Using a big number of facts, Atwood made a deep insight into the history of both English and French-Canadian literatures, compared them with American and European literary traditions as well as based her observations on an original concept, thus creating an invaluable introduction to Canadian literature for a wider public. In this article, we are going to give a brief review of the book which is practically unknown in Russia, focusing on the way Atwood interpreted such multicultural and quite little-known then issues as images of the First Nations and immigrants.
SINOPSIS PRELIMINAR DE LOS GÉNEROS HERPYZA C. WRIGHT Y DIOCLEA K. KUNTH (LEGUMINOSAE-PAPILIONOIDEAE) EN CUBA
Authors: Beyra Matos Ángela , Reyes Artiles Grisel , Hernández Valdés Laura
Published: October 2023

Se presenta una sinopsis preliminar de los géneros Herpyza C. Wright y Dioclea K. Kunth para Cuba. Se incluyen claves dicotómicas, descripciones taxonómicas, ilustraciones y datos químicos, cromosómicos, palinológicos, etnobotánicos, así como de distribución y ecología de los 4 taxones que se registran en el país dentro de dichos géneros. Aunque los resultados definen los caracteres de cada género se requiere de un posterior análisis molecular y biogeográfico de Herpyza junto con otros taxones de Phaseoleae para poder dilucidar las relaciones filogenéticas de dicho género con otros de Leguminosas.
EL MÉTODO MONTE CARLO COMO HERRAMIENTA PARA EVALUAR POROSIDAD EN CARBONES ACTIVADOS
Authors: Orrego Juan F. , Fernández Jhon J. , Mondragón Fanor
Published: October 2023

Se construyó un algoritmo Monte Carlo (MC) para obtener isotermas simuladas de la adsorción de nitrógeno sobre carbones activados, usando un modelo de poro tipo grieta cuyas paredes son láminas de carbono tipo grafito. Se evaluó el efecto de algunas variables como la densidad del material y el número de láminas de carbono. Las isotermas simuladas se utilizaron para obtener la distribución de tamaño de poro de algunos carbones activados preparados, los resultados fueron similares a los obtenidos usando un programa comercial basado en teoría de funcionales de densidad (DFT).
PTERIDÓFITOS DE COLOMBIA V. EL GÉNERO ANEMIA (SCHIZAEACEAE) EN COLOMBIA
Authors: Murillo-Pulido María Teresa , Murillo-A José
Published: October 2023

Se presenta una sinopsis de las especies de Anemia en Colombia: El género, formado por 14 especies y un híbrido, se distribuye ampliamente en el país desde el nivel del mar hasta ca 2500 m de altitud, con la mayor concentración de taxones en la región andina. Las especies más ampliamente distribuidas son A. ferruginea, A. phyllitidis y A. villosa. Se presenta una clave para las especies y para cada una se hace una descripción corta; además, se hacen anotaciones sobre la distribución geográfica y altitudinal.
EFECTO DEL CADMIO Y EL COBRE SOBRE EL FLUJO DE NITRÓGENO Y FÓSFORO EN LA INTERFASE AGUA-SEDIMENTO EN UNA LAGUNA COSTERA TROPICAL
Authors: Castro-González Maribeb , Campos Néstor Hernando
Published: October 2023

Se determinó el efecto del cadmio y el cobre sobre la circulación de amonio, nitrito y ortofosfato entre el sedimento y la columna de agua en la laguna costera tropical Ciénaga Grande de Santa Marta en el Caribe Colombiano; en el laboratorio se incubaron núcleos de sedimento tomados en dos sitios de muestreo con características contrastantes de salinidad, contenido de materia orgánica total y granulometría; durante cuatro períodos de muestreo, entre 1996 y 1997. El cadmio afectó los procesos de amonificación y de nitrificación en la mayoría de las épocas para los dos sitios de muestreo; el cobre afectó levemente la desnitrificación en río Sevilla, y el flujo de ortofosfatos no fue afectado por la adición de metales. Por otra parte, la densidad bacterial determinada en los sedimentos estuvo estrechamente relacionada con la salinidad, el contenido de materia orgánica, el tipo de sedimento y los flujos de nutrientes inorgánicos en la interfase agua-sedimento.
TRANSFORMACIÓN GENÉTICA DE PLANTAS PARA RESISTENCIA A VIRUS
Authors: Hodson de Jaramillo Elizabeth
Published: October 2023

El desarrollo de técnicas de manipulación genética constituye un valioso apoyo a los sistemas de mejoramiento convencional, principalmente en aquellas situaciones en las cuales el acceso a genes de interés se encuentra limitado. La utilización de cultivos transgénicos comerciales se ha expandido en el mundo en forma acelerada desde cuando se aprobó su uso en 1994, y son numerosos los beneficios que se han determinado para el agricultor y para el ambiente. El presente artículo presenta el contexto general de la manipulación genética de cultivos, un ejemplo de desarrollos en Colombia, relativos a la transformación genética de Passiflora edulis para darle resistencia a virus y también hace referencia a aspectos de bioseguridad.
CAMBIOS EN LA VEGETACIÓN DE SABANA OCASIONADOS POR LA PLANTACIÓN DE PINUS CARIBAEA EN VICHADA-COLOMBIA
Authors: Cortés-Pérez Francisco , Dueñas-Gómez Hilda del Carmen , Cardozo Hernán
Published: October 2023

En el Centro Las Gaviotas, en medio de la sabana no inundable, se ha establecido una plantación de pino (Pinus caribaea var. hondurensis), especie propia del Caribe y América Central. Con el fin de evaluar su efecto sobre la vegetación natural se efectuaron seis levantamientos de vegetación ubicados en la altillanura, sobre suelos de la serie Gaviotas, uno dedicado a ganadería extensiva y 5 plantados con pino de 4, 7, 10, 12 y 15 años de edad. Mediante comparaciones, análisis de variables estructurales y composición de la vegetación, se demuestra una modificación sustancial en la composición florística, fisionomía y estructura de la altillanura. Los principales cambios son: disminución en el número de especies y cobertura de gramíneas, ciperáceas y leguminosas, aumento del número de especies y cobertura de melastomatáceas, dilleniáceas, rubiáceas e hipericáceas y aparición de cuatro niveles de vegetación (herbáceo, arbustivo, arbolito y arbóreo) frente al herbáceo de sabana. En total se encontraron 186 especies; 80 en sabana y 159 en las plantaciones entre 4 y 15 años.
MODELOS DINÁMICOS DE GUERRA: EL CONFLICTO COLOMBIANO
Authors: Isaza D José Fernando , Campos R Diógenes
Published: October 2023

Se proponen algunos modelos de sistemas dinámicos deterministas que tienen como propósito describir conflictos armados, regulares e irregulares. Se hace énfasis especial en el caso de Colombia, en la que el conflicto involucra tres actores armados: Ejercito, guerrilla y paramilitares. Se sugiere un modelo que relaciona el número de efectivos ilegales (guerrilla y paramilitares) con el tamaño de la población susceptible de ingresar a grupos armados. Se concluye que es posible lograr un decrecimiento real del número de ilegales actuando política y económicamente en las zonas más vulnerables del país.
Methods of Order Diagnostic of Organizational Culture
Authors:   Saratov State University, Aksenovskaya L.N.
Published: October 2023

The author's technique of socially-psychological diagnostics of the organizational culture, developed on the basis of the order concept of organizational culture is presented. The general descriptions of a technique, forms of questionnaires are given. The way of use of questionnaires for diagnostics of organizational culture is shown.
Relation of the Emotional Burnout Syndrome and of the Value Sphere of a Personality in the Process of the Professional Socialization in the Extreme Conditions
Authors:   Saratov State University, Malyshev I.V.
Published: October 2023

The relation of the emotional burnout syndrome and of the value sphere of a personality on the basis of the dates of the factor analysis is considered in this paper. The social-psychological aspect of the burnout problem of a personality in the process of its professional socialization in the extremal conditions is substantiated.
META-ETIKA POLITIK DI ERA POST TRUTH (Studi Prilaku Elit politik Perspektif Etika Emotivis Bertrand Russell)
Authors: Huda Nurul , Maharani Septiana Dwiputri
Published: October 2023

AbstrakOrkestrasi politik di era post truth selain menyajikan kontestasi antar kelompok yang berkepentingan dengan menampilkan visi pembangunan ke depan, juga diramaikan penggunaan bahasa omong kosong (bullshit) dan berita palsu (fake news) oleh elit politik lewat berbagai media sosial. Tindakan etis para elit politik dengan menggunakan bullshit dan fake news di era post truth ini secara aksiologis tetap bisa dianalisis dalam perdebatan arus utama filsafat nilai yaitu obyektivisme dan subyektivisme yang berbeda dengan epistemologis yang umumnya dimaknai hanya sebagai akibat menurunnya relevansi teori-teori kebenaran. Melalui meta-etika Bertrand Russell, artikel ini berusaha membahas asal-usul etika, makna kebaikan, dan penilaian terhadap tindakan etis para elit politik. Pada akhirnya teori subyektif-emotivis  Russell memberikan legitimasi dalam menilai baik buruknya tindakan etis elit politik sebebas dan sebatas pada keinginan masing-masing.
ISTIADAT PERTABALAN DIRAJA SEBAGAI MEKANISME KE ARAH SISTEM PEMERINTAHAN BERDAULAT
Authors: Abd. Rahim Rahimin Affandi
Published: October 2023

Hugh Clifford  pernah menulis dalam catatannya The Court and Kampung -   ‘Until British interference changed the conditions which existed in Pahang, that country was the best type of an independent Malay State in the Peninsula, and much that was to be seen and learned in Pahang, in the days before the appointment of a British Resident, cannot now be experienced in quite the same measure anywhere else’. Kenyataan ini menyokong kuat wujudnya pentadbiran yang baik di negeri Pahang sebelum kedatangan British ke negeri ini. Mempunyai landskap geografi sebagai negeri paling luas di Semenanjung Malaysia, sudah pasti negeri ini memerlukan satu  sistem pentadbiran yang  berkesan dan kedaulatan raja memerintah yang hebat agar ia mampu berdiri teguh menyantuni sekian ramai rakyatnya. Periode Kesultanan Pahang Moden membuktikan mereka sebagai pendukung institusi ini begitu menghargai amalan istiadat nenek moyang sehingga ia menjadi premis asas pemerintahan di setiap generasi. Kajian ini bakal  mengupas istiadat pertabalan diraja negeri Pahang dengan penelitian terhadap  tatacara, falsafah dan akhirnya menjurus kepada satu dapatan bagaimana istiadat pertabalan diraja ini mampu berfungsi sebagai satu mekanisme kearah mewujudkan pemerintahan berdaulat. Metode yang digunakan ialah kaedah analisis kandungan  dengan memperinci falsafah disebalik tatacara istiadat pertabalan diraja yang diamalkan di negeri Pahang. Turut dihuraikan isi kandung sistem adat istiadat diraja yang diamalkan melalui catatan dari naskah-naskah  klasik. Hasilnya dapatlah disimpulkan, hebatnya sesebuah pemerintahan bukan sahaja ditandai oleh pembangunan fizikal malah ia turut digagaskan oleh sebuah institusi pemerintahan yang berdaulat dan mendapat kesetiaan penuh dari rakyat jelata.
NILAI TASAWUF PESANTREN DAN TRADISI SYAWIR SEBAGAI STRATEGI CULTURAL PROTECTION DARI LONE-WOLF TERRORISM
Authors: Hujatulatif Adha , Naim Chanif Ainun
Published: October 2023

AbstractThis article aims to present a fundamental element of pesantren culture which is considered capable of being a cultural strategy in responding to the shift in the modus operandi of terrorism which has reached the stage of lone-wolf terrorism. Pesantren education with the ethical values of Sufism that is owned places the kyai as a central figure who teaches the journey of life and is filled with metaphysical, cosmological, and psycho-religious doctrines which are expected to bring humans to perfection and life peace in total servitude to God through cleansing the heart of despicable qualities, adorn oneself with praiseworthy qualities and spread affection. The tarekat al-Ta'lim wa al-Ta'allum adopted makes pesantren focus on efforts to love science by learning and teaching as the highest position in life. Besides, the bahtsul masail method that is implemented in pesantren trains students to be able to accept differences of opinion as something natural. The three of them form a package of elements of the pesantren that are deeply rooted so that the pesantren and students indirectly have a strategy of resistance against extreme religious understanding.
TABU PERKAWINAN DALAM BUDAYA BANJAR
Authors: Sholihin Rahmat
Published: October 2023

AbstractThere are several prohibitions (taboos) in marriage according to Islamic law as confirmed in the Al-Quran and Hadith, such as: prohibition of marriage because of blood relations (nasab), breastfeeding or marriage. However, in Banjar culture, there are some additional taboos that people think are not good to do because they can have negative consequences. Viewing tradition from a Qur'anic perspective is an attempt to collaborate local traditions with universal religious teachings. This paper attempts to discuss the taboo issues surrounding marriage in Banjar culture according to the perspective of the Koran. This research method is qualitative with a field research model and uses an anthropological approach. The research locations are in three areas, namely: Banjarmasin, Martapura and Amuntai. The results of this study indicate that the prohibitions related to marriage contained in the Qur'an are universal and principled, while the prohibitions in Banjar culture are conditional and full of local wisdom. Understanding it wisely as a custom that contains benefits and benefits because it is loaded with good moral messages and does not violate religious teachings is a necessity, although not all Banjar people believe and practice it in the social reality of society.Keywords: Marriage taboo, Banjar culture, Al-Quran AbstrakAda beberapa larangan (tabu) dalam perkawinan menurut hukum Islam sebagaimana ditegaskan dalam Al-Quran dan Hadits, seperti: larangan kawin karena hubungan darah (nasab), sesusuan atau semenda. Namun dalam budaya Banjar ada beberapa pantangan tambahan yang menurut anggapan masyarakat tidak baik untuk dikerjakan karena dapat berakibat yang negatif. Memandang tradisi dari perspektif Qur’ani merupakan upaya untuk mengkolaborasikan tradisi lokal dengan ajaran agama yang bersifat universal. Tulisan ini berupaya untuk membahas masalah tabu sekitar perkawinan dalam budaya Banjar menurut perspektif Al-Quran. Metode penelitian ini bersifat kualitatif dengan model penelitian lapangan (field research) dan menggunakan pendekatan antropologi. Adapun lokasi penelitian di tiga wilayah, yaitu: Banjarmasin, Martapura dan Amuntai. Hasil dari penelitian ini menunjukkan bahwa larangan terkait perkawinan yang ada dalam Al-Quran bersifat universal dan prinsipil, sedangkan larangan dalam budaya Banjar bersifat kondisional dan sarat dengan kearifan lokal. Memahaminya dengan bijaksana sebagai adat yang mengandung maslahat dan manfaat karena sarat dengan pesan moral yang baik dan tidak menyalahi ajaran agama merupakan sebuah keniscayaan, walaupun tidak semua orang Banjar mempercayai dan mempraktekkannya dalam realitas sosial bermasyarakat.  Kata kunci: Tabu perkawinan, budaya Banjar, Al-Quran