bluuebunny/crossref_metadata_2025 huggingface dataset:
A review on the role of novel adipokine Isthmin-1 and Subfatin in human type 2 diabetes mellitus
Authors: Ahmed abed Baydaa , Othman Farhan Layla , Noori Salman Isam , Ehssan Safaa
Published: December 2023

Adipokines are essential for maintaining cardiovascular and metabolic balance. The term "adipokines" refers to peptides in the pancreas, brain, vascular system, liver, immune system and muscle. adipokines regulate  numbers of factors, such as energy expenditure, hunger, satiety, insulin sensitivity, and blood pressure, insulin secretion, adipogenesis and fat distribution, and that might make them  play a role in future pharmacological treatment strategies for obesity and metabolic diseases. Isthmin-1 (Ism-1) is a recently discovered insulin-like adipokine that suppresses hepatic lipids. According to recent research, Ism-1 can enhance lipid metabolism and treat metabolic disorders linked to type 2 diabetic mellitus (T2DM). The primary source of the protein subfatin (SUB) is white adipose tissue. Subfatin (SUB) is expressed in these following tissues:  adipose tissue, brain tissue, thymus gland, liver, activated human monocytes, spleen, omental adipose tissue, muscle, salivary glands and heart tissues. The SUB lowers insulin resistance to control glucose metabolism.  Isthmian-1 is a novel biomarker for early management and diagnosis of T2DM and has a beneficial effect in glucose homeostasis and might be therapeutic for diabetes. Subfatin also plays a role in glucose metabolism and insulin sensitivity, so it has significant effect in pathogenesis and complication of diabetes.
Polyphenylene Impregnated with Fullerene C60-Containing Oligophenylenes for CO2 Adsorption
Authors:   Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, str. 1, Moscow, 119334 Russia, Revizorova N. S. , Romanova V. S. ,   Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, str. 1, Moscow, 119334 Russia, Kovalev A. I. ,   Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, str. 1, Moscow, 119334 Russia, Kupriyanova D. V. ,   Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, str. 1, Moscow, 119334 Russia, Kharitonova V. G. ,   Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, str. 1, Moscow, 119334 Russia, Dorofeev А. S. ,   Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, str. 1, Moscow, 119334 Russia, Filatov S. N. ,   Mendeleev University of Chemical Technology, Miusskaya pl. 9, str. 1, Moscow, 125047 Russia, Khotina I. A. ,   Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, str. 1, Moscow, 119334 Russia
Published: December 2023

A network porous polyphenylene and fullerene-containing branched oligophenylenes have been synthesized to produce the polyphenylenes impregnated with the fullerene-containing compounds for CO2 adsorption. The resulting compounds were studied by IR spectroscopy and X-ray photoelectron spectroscopy (XPS). The analysis of the specific surface area was performed using the Brunauer–Emmett–Teller (BET) theory. The samples were tested tested for the efficiency of carbon dioxide adsorption. The most effective carbon dioxide adsorbent is found to be the polyphenylene impregnated with a triphenylamine-containing fullerene derivative.
Interfaith Tolerance in Tafsir Fath Al-Qadir and Tafsir of the Ministry of Religious Affairs of the Republic of Indonesia
Authors: Nando Etra , Jalwis Jalwis , Satria Oga
Published: December 2023

This article is based on the reality of life, especially Muslims in general, where there are still many Muslims who do not pay attention to religious tolerance in the life of the state and society. It can be seen from the reality that happened recently in Indonesia. The aim of this article is to look at the meaning and essence of tolerance in the Qur'an through the comprehension put forward by the tafsir experts by comparing the tafsir of Fath al-Qadir and the tafsir of the Ministry of Religious Affairs of Indonesia. The comparative method is carried out on the work of Imam Shaukani in the interpretation of Fath al-Qadir and the Qur'an and its Tafsir by the Ministry of Religious Affairs. This article finds that these two works of interpretation both emphasize that tolerance between religious communities only applies in the sociological aspect, not in the theological context. This argument was found through various verses in the Qur'an that talk about inter-religious relations, such as Q.S. Al-Baqarah: 256, Al-An'am: 108 and Al-Kafirun 1-6. In these verses, it is then illustrated that first, in the context of the da'wah passage there is no compulsion for non-Muslims to embrace Islam and it is strictly forbidden to hurt non-Muslims by mocking their God; second, there is no compromise for non-Muslims to invite to worship idols, because theological issues or monotheism are the identities and characteristics of a Muslim.
Pengetahuan Meningkatkan Pemberian Asi Eksklusif Pada Ibu di Makassar
Authors: Sundari Sundari , Masnilawati Andi
Published: December 2023

ASI merupakan makanan terbaik bagi bayi karena mengandung semua zat gizi yang dibutuhkan bayi dalam jumlah yang sesuai dan zat imunologik yang melindungi bayi dari infeksi. Hal ini disebabkan adanya antibodi yang terkandung dalam kolostrum ASI. Bayi yang diberi ASI dapat mengatur asupan energi berhubungan dengan respon internal dalam menyadari rasa kenyang. Tujuan dari penelitian ini untuk mengetahui gambaran tingkat pengetahuan dan pekerjaan dengan pemberian ASI eksklusif pada ibu di Makassar. Desain penelitian ini merupakan penelitian analitik dengan menggunakan rancangan cross sectional. Data kuantitatif kemudian dianalisis secara deskriptif berupa distribusi frekuensi karakteristik ibu yang memiliki anak 7-12 bulan. Analisis chi square digunakan untuk membandingkan data kategorik pengaruh meliputi pengetahuan dan status pekerjaan terhadap pemberian ASI eksklusif dengan menggunakan uji chi square dengan bantuan program komputer. Pengetahuan responden yang baik tentang ASI eksklusif (67,9%) dan pengetahuan tentang ASI eksklusif kurang (32,1%). Distribusi ibu yg bekerja (54%) dan distribusi ibu yang tidak bekerja (45,7%). Ibu yang tidak bekerja memilih tidak menyusui sebanyak 37,8%. Pengetahuan terhadap pemahaman ASI eksklusif ibu berhubungan dengan tindakan nyata ibu untuk memberikan ASI secara eksklusif pada bayi di Makassar. Pekerjaan ibu tidak berhubungan terhadap tindakan nyata ibu untuk memberikan ASI secara eksklusif pada bayi di Makassar. Kesimpulan penelitian menunjukkan bahwa pengetahuan yang baik tentang ASI eksklusif meningkatkan pemberian ASI eksklusif.
Pengaruh Pemberian KurmaAjwa (Phoenix dactylifera) terhadap Perubahan Tekanan Darah Ibu Hamil Hipertensi
Authors: Husaida Siti , Ikhtiar Muhammad , Nurlinda Andi
Published: December 2023

Hipertensi merupakan penyumbang kematian kedua ibu hamil di Indonesia setelah perdarahan. Kejadiannya masih meningkat setiap tahun.Penelitian ini bertujuan untuk menganalisis pengaruh pemberian kurma Ajwa terhadap perubahan tekanan darah pada ibu hamil yang hipertensi. Jenis penelitian ini adalah quasy eksperiment dengan pre-post test control design. Populasi penelitian adalah semua ibu hamil di RSIA Masyita dan Puskesmas Kassi-Kassi Kota Makassar. Sebanyak 40 orang ibu hamil dibagi menjadi dua kelompok intervensi, masingmasing 20 orang kelompok perlakuan dan 20 orang kelompok intervensi. Kelompok intervensi diberikan kurma Ajwa selama 30 hari dengan dosis 7 butir/hari (100 gr/hari), sedangkan kelompok kontrol diberikan penyuluhan nutrisi ibu hamil. Data dianalisis menggunakan uji Paired Samples Test dan uji Independent Samples Test. Hasil penelitian menunjukkan ada perbedaan yang signifikan sebelum dan setelah pemberian kurma Ajwa pada kelompok intervensi, baik pada tekanan darah sistol maupun diastol. Sementara pada kelompok perlakuan, diperoleh hasil tidak ada perbedaan yang signifikan sebelum dan setelah diedukasi tentang nutrisi kehamilan. Disimpulkan bahwa ada pengaruh pemberian kurma Ajwa terhadap perubahan tekanan darah pada ibu hamil yang hipertensi, sehingga disarankan pada ibu hamil rutin mengkonsumsi kurma Ajwa agar terhindar dari hipertensi kehamilan, dimulai saat trimester kedua kehamilan.
Keselamatan dan Kesehatan Kerja (K3) Sebelum Melaut pada Nelayan Penangkap Ikan di Kelurahan Lappa Kecematan Sinjai Utara
Authors: Rahman Irfandi , Mallapiang Fatmawaty , A.Fachrin Suharni , Abbas Hasriwiani Habo
Published: December 2023

Nelayan penangkap ikan adalah sebuah pekerjaan di atas permukaan perairan, dimana nelayan penangkap ikan berisiko tinggi untuk mengalami kecelakaan akibat kerja ataupun penyakit akibat kerja. Penelitian ini bertujuan untuk mengkaji penerapan keselamatan kerja pada nelayan penangkap ikan di Kelurahan Lappa dan mengkaji penerapan kesehatan kerja pada nelayan penangkap ikan di Kelurahan Lappa. Penelitian ini mengunakan metode penelitian kualitatif dengan pendekatan fenomenologi. Informan penelitian ini sebanyak 6 orang dengan kriteria nelayan penangkap ikan. Teknik pengumpulan data menggunakan wawancara mendalam, telaah dokumen dan obsevasi. Hasil penelitian menunjukkan bahwa keselamatan kerja sebelum melaut (memiliki pengalaman dan pengetahuan cuaca, berdoa, memeriksa kondisi perahu dan mesin, peralatan keselamatan). Sedangkan kesehatan kerja pada nelayan penangkap ikan sebelum melaut (memiliki kartu nelayan, mengetahui fungsi dan manfaat kartu nelayan, melakukan pemeriksaan kesehatan). Kesimpulan (1) Nelayan penangkap ikan penting mempersiapkan keselamatan sebelum melaut. (2) Nelayan penangkap ikan perlu menyiapkan alat kesehatan seperti kotak P3K, kartu nelayan, program penyuluhan kesehatan dan unit-unit kesehatan untuk nelayan penangkap ikan di Kelurahan Lappa Kecamatan Sinjai Utara Kabupaten Sinjai.
Upaya Peningkatan Harga Diri Rendah Dengan Terapi Aktivitas Kelompok (Stimulasi Persepsi) di Ruang Sub Akut Laki RSKD Provinsi Maluku
Authors: Tuasikal Hani , Siauta Moomina , Embuai Selpina
Published: December 2023

Harga diri rendah merupakan keadaan dimana individu mengalami evaluasi diri negatif tentang kemampuan dirinya. Pemberian TAK stimulasi persepsi yang efektif didukung dengan lingkungan tempat terapi diberikan, dan kemauan untuk berpartisipasi dalam kegiatan, maka diharapkan dapat mengatasi harga diri rendah juga dapat mempersepsikan yang di paparkan dengan baik dan tepat. Tujuan penelitian yaitu untuk menerapkan asuhan keperawatan jiwa pada Tn.Y dengan harga diri rendah dalam upaya meningkatkan harga diri dengan terapi aktivitas kelompok. Metode penelitian yang digunakan adalah metode penelitian deskriptif dengan studi kasus.. Hasil penelitian ini didapatkan bahwa sebelum dilakukan intervensi skor HDR Pasien 19 meningkat menjadi 24 yang diukur menggunakan kuisioner Rosenberg Self Esteem Scale. Kesimpulan penelitian yaitu terapi Aktivitas Kelompok (Stimulasi Persepsi) dapat meningkatkan harga diri klien.
Isolasi Bakteri Rhizosfer Tanaman Nilam (Pogostemon Cablin Benth.) Yang Berpotensi Sebagai Penghasil Senyawa Antibakteri Terhadap Bakteri Penyebab Infeksi Saluran Pencernaan
Authors: Maulidiyah Zakiya , Seniwati Seniwati , Rusli Rusli , Naid Tajuddin
Published: December 2023

Penelitian tentang isolasi bakteri rhizosfer pada tanaman nilam (Pogostemon cablin Benth.) telah dilakukan. Penelitian ini bertujuan untuk memperoleh isolat bakteri rhizosfer tanaman nilam yang berpotensi sebagai penghasil senyawa antibakteri terhadap bakteri penyebab infeksi saluran pencernaan. Tahap pertama, dilakukan isolasi bakteri yang berasal dari rhizosfer tanaman nilam. Uji skrining antibakteri dengan metode tanding, diperoleh isolat IBRN-3 dan IBRN-5 menghambat pertumbuhan semua bakteri uji. Isolat IBRN-3 dan IBRN-5 difermentasi. Hasil fermentasi diesktraksi dengan pelarut etil asetat menghasilkan ekstrak etil asetat fermentat kering. Dilakukan identifikasi Kromatografi Lapis Tipis terhadap ekstrak etil asetat IBRN-3 dan IBRN-5 menggunakan eluen kloroform: metanol (8:1) dan diilanjutkan dengan uji KLT-Bioautografi. Diperoleh hasil bercak pada IBRN-3 dengan nilai Rf 0.93 menghambat bakteri E. coli, S. aureus, nilai Rf 0.82 menghambat B. subtillis, S. dysenteriae, nilai Rf 0.64 menghambat S. aureus dan S. thypii, nilai Rf 0.89, 0.36, 0.24 menghambat S. dysenteriae, nilai Rf 0.84 dan 0.74 menghambat S. aureus. Sedangkan untuk IBRN-5, diperoleh bercak dengan nilai Rf 0.91 menghambat B. subtillis, E. coli S. thypii, nilai Rf 0.95 menghambat S. aureus, S. dysenteriae, nilai Rf 0.84 menghambat B. subtillis, S. thypii, nilai Rf 0.83 menghambat S. dysenteriae, dan nilai Rf 0,74 menghambat S. thypii. Disarankan menggunakan dosis isolat bakteri rhizosfer tanaman nilam yang sesuai untuk mencegah infeksi saluran pencernaan.
Perilaku Petani Padi dalam Penggunaan Pestisida di Desa Mandalahurip Kecamatan Jatiwaras Kabupaten Tasikmalaya
Authors: Suryani Dyah , Pratamasari Rossy , Suyitno Suyitno , Maretalinia Maretalinia
Published: December 2023

Pestisida merupakan senyawa kimia, organisme renik, virus, dan zat lain-lain yang digunakan untuk melindungi bagian tanaman. Petani mengharapkan hasil dari produk pertanian meningkat sehingga petani menggunakan pestisida untuk menghilangkan hama dan gulma. Akan tetapi, penggunaan pestisida memiliki efek samping yang negatif yaitu berkurangnya keanekaragaman hayati dan dapat membunuh makhluk yang bukan sasarannya. Penelitian ini bertujuan mengetahui hubungan pengetahuan, sikap, umur, tingkat pendidikan, dan masa kerja dengan perilaku penggunaan pestisida. Jenis penelitian adalah penelitian analitik observasional dengan pendekatan cross sectional. Subjek penelitian adalah petani Desa Mandalahurip yang berjumlah 96 petani. Instrumen penelitian yaitu kuesioner. Analisis data menggunakan analisis bivariar dengan uji Fisher’s. Hasil analisis menunjukkan ada hubungan antara pengetahuan dengan perilaku penggunaan pestisida (p-value=0.019), ada hubungan antara sikap dengan perilaku penggunaan pestisida (p-value=0.000), tidak ada hubungan antara umur dengan perilaku penggunaan pestisida (p-value=0.531), tidak ada hubungan antara tingkat pendidikan dengan perilaku penggunaan pestisida (p-value=0.353), ada hubungan antara masa kerja dengan perilaku penggunaan pestisida (p-value=0.015). Kesimpulan penelitian ini adalah terdapat hubungan antara pengetahuan, sikap, dan masa kerja dengan perilaku penggunaan pestisida pada petani padi dan tidak ada hubungan antara umur dan tingkat pendidikan dengan perilaku penggunaan pestisida pada petani padi. Disarankan tidak selalu menggunakan pestisida kimia, dan selalu menggunakan APD secara lengkap pada saat melakukan kegiatan pengaplikasian pestisida.
Pelaksanaan Fungsi Manajemen Dan Kondisi Kerja Berhubungan Dengan Kepuasan Kerja Perawat
Authors: Mita Mita , Ali Maulana Muhammad
Published: December 2023

Kepuasan kerja merupakan bagian dari pengintegrasian sumber daya manusia, menjadi salah satu respon emosional atas pekerjaan yang telah dilakukan. Tujuan penelitian ini untuk menganalisa hubungan antara pelaksanaan fungsi manajemen, kondisi kerja dan kepuasan kerja perawat di ruang rawat inap rumah sakit daerah kota Baubau. Jenis penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross sectional study. Sampel sdalam penelitian ini adalah 153 perawat yang bekerja diruang rawat inap, yang di peroleh dengan menggunakan teknik total sampling. Pengumpulan data menggunakan kuesioner dengan skala likert. Analisa data univariat melalui tabel frekuensi dan analisa bivariat menggunakan uji Spearman. Hasil penelitian menunjukan ada hubungan antara fungsi manajemen dan kepuasan kerja (p=0,001) dan ada hubungan antara kondisi kerja dan kepuasan kerja (p=0,036). Pelaksanaan fungsi manajemen yang baik oleh kepala ruangan dan kondisi kerja yang mendukung perawat dalam menjalankan tugas dan tanggungjawab bagi pelayanan keperawatan, akan mempengaruhi kepuasan kerja perawat. Hasil penelitian diharapkan dapat menjadi pertimbangan bagi rumah sakit terutama pihak manajemen rumah sakit untuk memperhatikan kondisi kerja perawat dan pelaksanaan manajemen diruangan sehingga dapat mempertahankan kepuasan kerja perawat.
Pengetahuan, Sikap, Kebiasaan Merokok, Aktifitas Fisik, dan Kepatuhan Minum Obat Berhubungan Dengan Pengedalian Hipertensi
Authors: Hia Jaya , Trisman Triasman , Simajorang Simajorang , J Hadi Anto
Published: December 2023

Hypertension is the highest cause of death and illness. History of hypertension along with unhealthy lifestyles such as smoking, physical activity and medication adherence. This study aims to determine the factors associated with controlling hypertension in the Working Area of â€‹â€‹UPT Puskesmas Padang Bulan Kota Medan. This type of research is quantitative with a cross sectional study design. Population and sample are patients who come to visit and have their health checked by sampling technique using accidental sampling as many 100 people and univariate, bivariate and multivariate data analysis. The results of research that have been carried out obtained that there is a significant relationship of knowledge (p = 0.006), attitudes (p = 0.011), smoking habits (p = 0.018), physical activity (p = 0.017), compliance with taking medication (p = 0,000) with controlling hypertension. Compliance with medication drinks is most dominant with hypertension control (Sig 0.001 and Exp 24.048). The conclusion is that there is a relationship between knowledge, attitude, smoking habits, physical activity, medication adherence with hypertension control. It is expected that the puskesmas make prevention efforts, or overcome the problem of hypertension by conducting hypertension counseling / counseling to patients.
Sustainable Finance: A study on Malaysia’s Regulatory Framework on Sustainable Banking and its Implementation By Selected Islamic Banks in Malaysia in Support of Sustainable Development Goals
Authors: Rastam Shahrom Zuraida , Sherin Kunhibava
Published: December 2023

In 2018, Bank Negara Malaysia (BNM), the central bank of Malaysia issued the Strategy Paper on Value-based Intermediation (VBI). VBI aims to deliver the intended outcomes of Shariah through practices, conduct and offerings by Islamic financial institutions (IFI)s that generate positive and sustainable impact to the economy, community, and environment. To assist IFIs to translate VBI into real banking practices and offerings BNM also issued guidance documents, one of which is the guidance document on Value-based Intermediation Financing and Investment Impact Assessment Framework (VBIAF). BNM has also issued the Climate Change and Principle-based Taxonomy (CCPT) which specifically addresses climate change. This article examines the VBI, VBIAF and the CCPT and investigates the adoption of the VBI, VBIAF and CCPT by three Islamic banks (IB)s in Malaysia. It aims to provide an understanding of the regulatory frameworks and how the adoption of the frameworks has influenced the offerings, practices, and operations of these banks towards the triple bottom line approach in support of sustainable development goals. From the study it is found that the IBs have initiated the implementation of an impact-based risk assessment and management consistent with the VBIAF and assessment of climate risk based on the CCPT, however these are still at the preliminary stages for the IBs. Nonetheless, what is encouraging is that all the three IBs have implemented various VBI-related initiatives in line with the underpinning thrusts of VBI. This paper illustrates how these various VBI-related initiatives by the IBs have assisted the banks in supporting sustainable development.
Religious Commitment and Gratitude as a Strategy for Promoting Student Mental Health
Authors: Sholichatun Yulia , Mangestuti Retno , Suryani Suryani , Huroniyah Fuadatul , Marwing Arman
Published: December 2023

Despite global students' mental health problems being prevalent, adequate attention and resources to treat mental health problems are still lacking. Meanwhile, several studies found that religious commitment and gratitude can play an essential role in addressing the issue of mental health problems. This study explored religious commitment to promote mental health and gratitude as moderating variables to address this gap. This study used the Brief Scale of Mental Health 12, the General Mental Health Questionnaire (GHQ-12), the Gratitude Resentment and Appreciation Test (GRAT), and the Religious Commitment Inventory (RCI–10) scales. Data were taken from 320 students of four state Islamic Universities in East Java, Indonesia. This study utilized descriptive and regression analysis techniques. The result of the data analysis demonstrated three main findings as follows. First, the students had a high level of mental health. Second, religious commitment positively affected mental health. Third, gratitude could become a variable that strengthens the relationship between religious commitment and mental health. Research implication in education is attempting to improve mental health among students not merely on the religious commitment but also on emphasizing systematic ways to develop gratitude in students' daily lives as a moderator that plays a role in maintaining the relationship between mental health and religious commitment. This study was based solely on a quantitative approach; therefore, a mixed-method model is recommended for further investigation to understand the process of improving mental health through religious commitment and students' gratitude better.
Mindfulness and Academic Resilience of Suburban High School Students
Authors: Putra Ivandro Arsena , Huwae Arthur
Published: December 2023

Being a suburban high school student is complicated. They must overcome numerous challenges, obstacles, and risks to fulfil their role as high school students. High school students need more facilities and infrastructure to develop their full potential, which can result academic setbacks. Academic resilience and mindfulness are two factors that can assist individuals in avoiding experiencing setbacks during the learning process. This study aimed to examine the correlation between mindfulness and academic resilience among suburban high school students. The research employed a quantitative method and correlational design. The study utilized the incidental sampling technique in which the sample comprised of 535 suburban high school students in Semarang Regency. The employed research instruments were the Five Facet Mindfulness Questionnaire (FFMQ) (α = .914) and the Academic Resilience Scale (ARS-30) (α = .958). The data were analysed using Spearman's Rho correlation test. The study demonstrated weak significant positive correlation between mindfulness and academic resilience (r = .162 and sig = .000). This demonstrated that mindfulness was one of the factors associated with increased academic resilience among suburban high school students.
ANALISIS HUBUNGAN ANTARA REKRUTMEN GURU HONORER DAN KINERJA GURU PNS TERHADAP PROFESIONALISME GURU DI PROVINSI MALUKU UTARA JENJANG PENDIDIKAN SMA, SMK, DAN SLB
Authors: Karim Wahid Abd , Hasyim Wahab , Fahri Johan
Published: December 2023

Guru adalah orang yang memiliki keahlian khusus dan berprofesi sebagai pendidik profesional yang terlibat dalam dunia pendidikan, di mana tugasnya tidak hanya sekedar mentransfer ilmu ke peserta didiknya, akan tetapi lebih dari itu. Guru mempunyai beban atau tugas untuk menumbuhkan kemampuan peseta didik agar dapat meningkatkan dan mencerdaskan kehidupan bangsa. Hasil verifikasi data guru oleh bidang GKT DIKBUD provinsi Maluku Utara per-tanggal 31 desember 2021, menunjukan bahwa terjadi peningakatan jumlah guru honorer pada jenjang pendidikan SMA, SMK, dan SLB, bila dibandingkan dengan tahun 2020 yang lalu, yaitu dengan rincian jumlah guru PNS dan gur honorer di tahun 2020 sebanyak 2.403 orang guru PNS, dan 2.749 orang guru non PNS, sedangkan di tahun tahun 2021 sebanyak 2.511 guru PNS dan 3.296 guru honorer, yang tersebar di 10 kabupaten dan kota di Provinsi Maluku Utara.Penelitian ini bertujuan untuk melihat hubungan antara rekrutmen guru honorer dengan profesionalisme guru dan hubungan antara kesejahteraan guru dengan profasionalisme guru. Penelitian dilakukaan kepada guru honorer dan guru PNS yang berjumlah 86 guru sebagai responden menggunakan Teknik angket dengan analisis regresi ganda menggunakan aplikasi SPSS.25. hasil penelitian yang diperoleh adalah terdapat hubungan yang positif maupun negated dan signifikan antara rekrutmen guru honorer, kesejahteraan guru dengan profesionalisme guru.
Leadership Evaluation of David Brailer: Insights From Health Informatics and Public Service
Authors: Gransberry Christopher K.
Published: December 2023

This study assesses the leadership style and impact of David Brailer, the former United States National Health Information Technology Coordinator, renowned for his contributions to health informatics. The study employs several methodologies: an examination of both positive and negative leadership attributes, an analysis of his leadership style, and an exploration of his vision-defining abilities. Central to this investigation is the analysis of organizational leadership, undertaken through an innovative leadership theory and guiding principles, which are designed to uncover strategies for enhancing leadership in a rapidly evolving society. Brailer’s extensive background in health informatics, coupled with his tenure at the U.S. Department of Health and Human Services, provides a rich foundation for this study. In 2004, President George W. Bush appointed him as the inaugural Health Information Technology Czar, marking a historic moment in advancing electronic health records and the digitization of healthcare information, health informatics and public service.
PENGARUH BRAND AWARENESS DAN BRAND IMAGE TERHADAP PURCHASE INTENTION PADA WULING AIR EV MELALUI MEDIASI CUSTOMER TRUST.
Authors:   Universitas Katolik Widya Mandala Surabaya, Verado Vegga , Budiarsi Sri Yunan ,   Universitas Katolik Widya Mandala Surabaya, Handayani Yuliasti Ika ,   Universitas Katolik Widya Mandala Surabaya
Published: December 2023

Nowadays technology has developed very rapidly and over time is able to produce products that are more environmentally friendly, for example in the automotive industry one of the contributors to pollution is motorized vehicles but with technological developments they are now able to present electric motorized vehicles that are environmentally friendly. The purpose of this study is to determine the effect of brand awareness and brand image on purchase intention at Wuling Air EV through mediation of customer trust. The population used in this study were people who knows and have interest in Wuling Air EV in Surabaya. The sampling technique uses non-random sampling with a purposive sampling technique. The number of samples obtained was 200 respondents. The variables examined in this study are brand awareness, brand image, customer trust and purchase intention.
Jogos e brincadeiras no ensino de Matemática: análise de um Livro do PNLD 2022
Authors: Silva Kemilly Layane da , Alencar Edvonete Souza de
Published: December 2023

Essa investigação tem como objetivo identificar os jogos e brincadeiras potencializadores para o ensino de Matemática apresentados em um livro didático da Educação Infantil do Programa Nacional do Livro e do Material Didático (PNLD) 2022. A metodologia utilizada foi de caráter qualitativo do tipo documental. Com esta pesquisa, pretendeu-se contribuir com os estudos sobre a temática, de forma a acrescentar e ampliar os conhecimentos adquiridos referentes ao ensino de Matemática, evidenciando principalmente os jogos e brincadeiras. Conforme os resultados da presente pesquisa, o livro analisado já trabalha com a ludicidade no ensino da Matemática, no qual foi possível identificar que contempla em seus conteúdos, os jogos e brincadeiras. Consequentemente, ele também contribui para a formação de estratégias na aprendizagem.
Methodology for entities’ non-financial reporting quality assessment
Authors:   SESE “The Academy of Financial Management”, IEFYMENKO Tetiana , LOVINSKA Ljudmyla ,   Kyiv National Economic University named after Vadym Hetman, OLIINYK Yana ,   SESE “The Academy of Financial Management”, KUCHERIAVA Maria ,   SESE “The Academy of Financial Management”, KORYTNYK Liliya ,   SESE “The Academy of Financial Management”
Published: December 2023

Introduction. Currently, the task of harmonizing domestic legislation in the field of accounting and reporting with the directive requirements of the EU has arisen, in particular in terms of conceptual and terminological differences, the mechanism for collecting and processing data from non-financial reports of enterprises and the lack of a proper system for ensuring their quality. Problem Statement. The existence of a wide variety of approaches to the preparation of non-financial reporting by enterprises ,on the one hand , and the lack of regulation in domestic legislation of approaches to disclosure of information on sustainable development by business entities lead to a decrease in the quality of reporting data (comparability, transparency, reliability), on the other hand. The purpose is to scientifically substantiate the methodological tools for assessing the quality of non-financial reporting of enterprises. Methods: bibliographic analysis, graphical method as well as analysis and synthesis methods were used. Results. In the context of the development of the concept of quality of non-financial reporting and its reflection in regulatory documents of various levels, it has been identified that, despite the global level of its distribution, there is currently no clear understanding of the definition of quality of non-financial reporting as the basis for building a system for its assessment. The authors have developed the conceptual and categorical apparatus in the studied area by formulating a definition of the concept of “quality of non-financial reporting”. Conclusions. The paper proposes a draft Methodology for entities’ non-financial reporting quality assessment with regard to disclosure of information to justify the provision of state support to overcome the consequences of the pandemic of particularly dangerous infectious diseases (draft Methodology) is an attempt to solve it. The document is based on internationally recognised standards for corporate sustainability disclosures: IFRS S1 “General Requirements for Disclosure of Sustainability-related Financial Information”; IFRS S2 “Climate-related Disclosures”; European Sustainability Reporting Standards (ESRS 1 “General Principles”). The draft Methodology proposed in this paper includes three sections: General provisions; Procedure for assessing the quality of non-financial reporting; Organisation of the quality assessment of non-financial reporting at the enterprise.
Justification of some measures to minimize macrofiscal risks in Ukraine
Authors:   SESE “The Academy of Financial Management”, KULYK Volodymyr
Published: December 2023

Introduction. Measures to minimize macro-fiscal risks in Ukraine are substantiated, based on the reduction of volatility of incomes formed as a result of the reproduction of the national economy, quality assurance of macroeconomic proportions. Problem Statement. Comparative analysis of reproductive processes in the national economy in the context of the formation of the system of gross and net income of consolidated national accounts with the application of economic and statistical methods of analysis.Justification of the results of comparative analysis to minimize macro-fiscal risks. Purpose. Justification of measures to minimize macro-financial risks in Ukraine based on the study of the formation of the income system in the national economy and the risks associated with them. Methods. The basis of the study was official statistical data - dynamic series of indicators of consolidated national accounts. The balance method and methods of economic and statistical analysis were used. Results. A system of indicators is proposed for statistical assessment of the volatility of the reproduction processes of the national economy. The formation of the income system and related risks for the economy of Ukraine and Germany has been studied. Measures to minimize macro-financial risks in Ukraine are substantiated. Comparative studies between countries on a single methodological basis made it possible to determine the strengths and weaknesses of the economic cycle of the compared countries, to identify the problems of economic reproduction. Conclusions. Minimization of macro-fiscal risks lies in the maintenance of macroeconomic proportions favourable to economic stability and economic growth, stability and consistency of revenue and expenditure items of the state budget.
Status of Pesticide Use among Thyme (Thymus vulgaris) Crop Farmers in North West Bank, Palestine
Authors: Alimari Abdallah Issam
Published: December 2023

The data were collected to diagnose the current status of pesticide use on thyme crops (Thymus vulgaris). In total, 111 questionnaires were used to calculate the means, standard deviation, and percentages of farmers’ responses. Chi-square (χ2) and T-tests were employed to test the associations between pesticide application practices and demographic variables, recipients of extension, sources of farmer information, production, and marketing. The results showed that 69.7% of farmers used 23 insecticides, and 11.8% of the pesticides were not suitable for pest control. Additionally, 73.5% were not compatible with the safety period. There was a 29.2% increase in pesticide concentration from the recommended amount and a 32.4% increase in the number of spraying times during the season. Farmer commitment to pesticide use instructions was moderate, with a mean of 2.8 ± 0.68. In total, 51.4% of farmers received extension services, and 47.2% relied on their local experience for pesticide practices. Extension services influenced the overused dose. Most farmers did not participate in specialized courses or field days, and no regulatory extension was carried out by institutions for them. They did not adhere to a production guide or obtain a quality certificate. The application of different pesticides did not increase the productivity of thyme. The study findings revealed alarming trends in current farmer practices, with significant implications for crop, farmers, and consumer safety. They underscore the pressing need for targeted interventions, including improved extension services and increased farmer awareness to promote responsible pesticide use.
The age and sources of stream water in a boreal forest watershed in the permafrost region: a case study of a watershed in northeast China
Authors: Xiao Xiang , Cai Tijiu , Duan Liangliang
Published: December 2023

Determining the age and sources of stream water is critical for understanding the watershed hydrological processes and biogeochemical cycle. In this study, daily isotope data of rainfall and runoff, as well as continuously monitored conductivity data from June to October in 2019 in-Laoyeling(LYL) watershed located in permafrost region of northeastern China were used to separate streamflow components through the application of two independent methods: isotope-based hydrograph separations (IHS) and the conductivity mass balance (CMB) methods. The results showed that stream water in a boreal forest watershed with permafrost of the Daxing’an Mountains is mainly composed of pre-event water. Although the IHS method is more sensitive and provides more details than the CMB method, the results of both methods show a similar trend. The average value of the young water fractions (Fyw) for those aged less than 65 days is 5.6%, while the mean transit time (MTT) was calculated to be 3.33 years. These findings enhance our understanding of the fundamental characteristics of runoff generation mechanisms and changes in runoff components in permafrost regions. Such knowledge is crucial for effective regional water resource management under the context of climate change, such as construction of water conservancy facilities and prediction of flood and drought disasters.
Economic loss assessment of typhoon-induced storm surge disasters in the South China Sea based on GSA-BP model
Authors: Zhang Yuxuan , Zhang Tianyu , Shen Wenqi , Ou Zijing , Zhang Junping
Published: December 2023

In the context of global climate warming and rising sea levels, the frequency of tropical cyclones in the South China Sea region has shown a significant upward trend in recent years. Consequently, the coastal areas of the South China Sea are increasingly vulnerable to storm surge disasters induced by typhoon, posing severe challenges to disaster prevention and mitigation in affected cities. Therefore, establishing a multi-indicator assessment system for typhoon storm surges is crucial to provide scientific references for effective defense measures against disasters in the region. This study examines 25 sets of typhoon storm surge data from the South China Sea spanning the years 1989–2020. A comprehensive assessment system was constructed to evaluate the damages caused by storm surges by incorporating the maximum wind speed of typhoons. To reduce redundancy among multiple indicators in the assessment system and enhance the stability and operational efficiency of the storm surge-induced disaster loss model, the entropy method and bootstrap toolbox were employed to process post-disaster data. Furthermore, the genetic simulated annealing algorithm was utilized to optimize a backpropagation neural network intelligent model (GSA-BP), enabling pre-assessment of the risks associated with storm surge disasters induced by typhoon and related economic losses. The results indicate that the GSA-BP model outperforms the genetic algorithm optimized BP model (GA-BP) and the simulated annealing algorithm-optimized BP model (SA-BP) in terms of predicting direct economic losses caused by storm surges. The GSA-BP model exhibits higher prediction accuracy, shorter computation time, and faster convergence speed. It offers a new approach to predicting storm surge losses in coastal cities along the South China Sea.
Analysis and quantitative identification of guided wave propagation mechanism in concrete
Authors: Su Chenhui , Zhang Yuhang , Tang Lin , Zhang Wenchao
Published: December 2023

Concrete is widely used in bridges, tunnels, nuclear power plants and other buildings, the damage of concrete will bring significant safety hazards for the building, therefore, detecting concrete damage is of great significance. In this paper, the propagation characteristics of guided waves in concrete plates are investigated, and finite element simulation is used to analyze the sensitivity of guided waves to the damage of concrete materials under different excitation frequencies. Simulation experiments on guided wave propagation are performed on concrete materials containing damage in the excitation frequency range from 25 to 100 kHz. The signals received by the sensors are analyzed in the time domain, while the reflected wave signals resulting from the contact of the signals with the damage are analyzed in the frequency domain. The results show that the excitation frequencies of 25 and 60 kHz are more sensitive to damage, and the quantitative identification of damage without reference can be realized by using the peak signals in the frequency domain at different excitation frequencies.
Ultrasonographic manifestations and misdiagnosis analysis of ovarian leiomyoma
Authors: Zhang Min , Hong Yan , Wang Li , Qin Ling-Ling , Jing Xiang-xiang
Published: December 2023

Objectives

Ovarian leiomyomas (OLs) are rare and account for only 0.5 to 1% of benign ovarian tumors. This study investigated the ultrasonographic manifestations of OL and the potential reasons for misdiagnosis.

Methods

Between July 2018 and July 2023, 7 patients diagnosed with OL by surgical pathology and immunohistochemistry were enrolled in this retrospective analysis. Ultrasound (US) examinations were performed before surgery. Clinical characteristics, pathological findings, ultrasonographic manifestations, and treatment were reviewed.

Results

The mean age of the 7 patients was 39.0 ± 11.57 years, with a disease course of 0.1 to 24 months. All ovarian leiomyomas were unilateral. Four cases occurred in the right ovary, and three cases occurred in the left ovary. All lesions presented as hypoechogenic, well-circumscribed, round or oval in shape, and regular in morphology. No significant blood flow signal was detected peripheral to or inside the mass in 3 cases (42.8%), and a minimal flow signal was detected peripheral to or inside the mass in 4 cases (58.2%). A total of 7 ultrasonographic images of OL were misdiagnosed: 1 patient was misdiagnosed with subserosal uterine leiomyoma, and 6 patients were misdiagnosed with a tumor in the ovarian thecoma–fibroma group.

Conclusion

The imaging manifestation of OL lacks specificity; thus, preoperatively distinguishing OL from other ovarian tumors and subserosal uterine leiomyomas is difficult. Immunohistochemistry may be helpful for the definitive diagnosis of OL. The possibility of ovarian leiomyoma should be considered in patients with uterine leiomyomas coexisting with an adnexal ovarian solid mass.
Pemphigus: trigger and predisposing factors
Authors: Moro Francesco , Sinagra Jo Linda Maria , Salemme Adele , Fania Luca , Mariotti Feliciana , Pira Anna , Didona Biagio , Di Zenzo Giovanni
Published: December 2023

Pemphigus is a life-threatening autoimmune blistering disease affecting skin and mucous membranes. Despite its etiopathogenesis remains largely unknown, several trigger and predisposing factors have been reported. Pemphigus is caused by autoantibodies that target desmoglein 1 and desmoglein 3, impacting desmosome function. However, circulating autoantibodies are often the consequence of a precipitating factor that occurs in predisposed individuals. This review aims to describe and discuss almost all trigger and predisposing factors reported as possible or probable cause of the disease. Among the reported trigger factors that may induce or exacerbate pemphigus, we have found of particular interest: drug intake (especially thiol- and phenol-containing compounds), vaccines, infections, as well as some reports about pregnancy, radiations, emotional stress, pesticides and physical trauma. Moreover, we discuss the possible role of food intake in pemphigus onset and particular attention is given to dietary factors containing thiol, phenol and tannin compounds. A trigger factor is “the straw that breaks the camel’s back,” and often acts together with predisposing factors. Here we discuss how pemphigus onset may be influenced by genetic susceptibility and comorbidities like thyroid diseases, malignancies and other autoimmune disorders.

To identify other hitherto unknown trigger and predisposing factors, well designed prospective studies are needed. In this context, future research should explore their connection with the aim to advance our understanding of pemphigus pathogenesis.
Research on the quality markers of antioxidant activity of Kai-Xin-San based on the spectrum–effect relationship
Authors: Shan Xiaoxiao , Yang Xuan , Li Dawei , Zhou Lele , Qin Shaogang , Li Junying , Tao Wenkang , Peng Can , Wei Jinming , Chu Xiaoqin , Wang Haixuan , Zhang Caiyun
Published: December 2023

Background: Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern pharmacological research has found that KXS has significant therapeutic efficacy on nervous system diseases, which is related to its antioxidant activity. However, the antioxidant material basis and quality markers (Q-makers) of KXS have not been studied. Objective: The objective of this study is to explore the Q-makers of antioxidant activity of KXS based on spectrum-effect relationship.

Methods: Specifically, the metabolites in KXS extracts were identified by UPLC-Q-Exactive Orbitrap MS/MS. The fingerprint profile of KXS extracts were established by high-performance liquid chromatography (HPLC) and seven common peaks were identified. Meanwhile, 2, 2-diphenyl-1-picrylhydrazyl (DPPH) test was used to evaluate the free radical scavenging ability of KXS. The spectrum-effect relationship between its HPLC fingerprint and DPPH free radical scavenging activity was preliminarily examined by the Pearson correlation analysis, grey relation analysis (GRA), and orthogonal partial least squares discrimination analysis (OPLS-DA). Further, the antioxidant effect of KXS and its Q-makers were validated through human neuroblastoma (SH-SY5Y) cells experiment.

Results: The results showed that 103 metabolites were identified from KXS, and the similarity values between HPLC fingerprint of twelve batches of KXS were greater than 0.900. At the same time, the results of Pearson correlation analysis showed that the peaks 8, 1, 14, 17, 18, 24, 16, 21, 15, 13, 6, 5, and 3 from KXS were positively correlated with the scavenging activity values of DPPH. Combined with the results of GRA and OPLS-DA, peaks 1, 3, 5 (Sibiricose A6), 6, 13 (Ginsenoside Rg1), 15, and 24 in the fingerprints were screen out as the potential Q-makers of KXS for antioxidant effect. Besides, the results of CCK-8 assay showed that KXS and its Q-makers remarkably reduced the oxidative damage of SH-SY5Y cells caused by H2O2. However, the antioxidant activity of KXS was decreased significantly after Q-makers were knocked out.

Conclusion: In conclusion, the metabolites in KXS were successfully identified by UPLC-Q-Exactive Orbitrap MS/MS, and the Q-makers of KXS for antioxidant effect was analyzed based on the spectrum-effect relationship. These results are beneficial to clarify the antioxidant material basis of KXS and provide the quality control standards for new KXS products development.
Variety ACEs and risk of developing anxiety, depression, or anxiety-depression co-morbidity: the 2006–2022 UK Biobank data
Authors: Yu Peilin , Jiang Zhou , Zheng Chu , Zeng Ping , Huang Lihong , Jin Yingliang , Wang Ke
Published: December 2023

Objectives

Adverse childhood experiences (ACEs) and anxiety-depression co-morbidity are attracting widespread attention. Previous studies have shown the relationship between individual psychiatric disorders and ACEs. This study will analyze the correlation between anxiety-depression co-morbidity and different levels of ACEs.

Methods

Seven categories of ACE and four classifications of psychiatric disorders were defined in a sample of 126,064 participants identified by the UK Biobank from 2006–2022, and correlations were investigated using logistic regression models. Then, to explore nonlinear relationships, restricted spline models were developed to examine differences in sex and age across cohorts (n = 126,064 for the full cohort and n = 121,934 for the European cohort). Finally, the impact of the category of ACEs on psychiatric disorders was examined.

Results

After controlling for confounders, ACEs scores showed dose-dependent relationships with depression, anxiety, anxiety-depression co-morbidity, and at least one (any of the first three outcomes) in all models. ACEs with different scores were significantly positively correlated with the four psychiatric disorders classifications, with the highest odds of anxiety-depression co-morbidity (odds ratio [OR] = 4.87, 95% confidence intervals [CI]: 4.37 ~ 5.43), p = 6.08 × 10−178. In the restricted cubic spline models, the risk was relatively flat for females at ACEs = 0–1 and males at ACEs = 0–2/3 (except in males, where ACEs were associated with a lower risk of anxiety, all other psychiatric disorders had an increased risk of morbidity after risk smoothing). In addition, the risk of having anxiety, depression, anxiety-depression co-morbidity, and at least one of these disorders varies with each category of ACEs.

Conclusion

The prevalence of anxiety-depression comorbidity was highest across ACE scores after controlling for confounding factors and had a significant effect on each category of ACEs.