bluuebunny/crossref_metadata_2025 huggingface dataset:
THE СOURSE AND OUTCOMES OF TREATMENT OF PATIENTS WITH TYPICAL HEMOLYTIC-UREMIC SYNDROME
Authors: Музуров Александр Львович , Эмирова Хадижа Маратовна , Панкратенко Татьяна Евгеньевна , Абасеева Татьяна Юрьевна , Генералова Галина Анатольевна , Бабаев Бобо Домуллаевич , Кварацхелия Малхаз Викторович , Попа Анатолий Валентинович , Мстиславская Софья Александровна , Майоров Алексей Дмитриевич
Published: February 2023

Статья посвящена важной проблеме детской реаниматологии и нефрологии - типичному гемолитико уремическому синдрому (тГУС). Проведено ретроспективное исследование 267 больных с тГУС за последние 5 лет. Проведена оценка клинико лабораторных данных больных и результатов лечения. Летальность составила 2,27%. Выявлено, что заместительная почечная терапия потребовалась 74,5% пациентам, основным методом заместительной почечной терапии (55,3%) был перитонеальный диализ. Анурия в дебюте заболевания являлась неблагоприятным фактором, ассоциированным с повышенным риском полиорганного поражения, вовлечения центральной нервной системы, летального исхода, а также длительной заместительной почечной терапии и неполного восстановления функций почек. С анурией ассоциирован более высокий уровень маркеров воспаления, гемолиза, тромбообразования и более низкий уровень компонента комплемента С3, а также большая длительность тромбоцитопении, что позволяет рассматривать эти показатели как предикторы тяжести тГУС. Развитие острого повреждения почек с анурией у больных с тГУС по большинству показателей значительно ухудшает прогноз пациентов и является фактором неблагоприятного прогноза у больных с тГУС.

The article is devoted to an important problem of pediatric resuscitation and nephrology - a typical hemolytic uremic syndrome (tHUS). A retrospective study of 267 patients with tHUS over the past 5 years was carried out. The evaluation of clinical and laboratory data of patients and treatment results was carried out. Mortality was 2.27%. It was revealed that renal replacement therapy was required in 74.5% of patients, the main method of renal replacement therapy (55.3%) was peritoneal dialysis. Anuria at the onset of the disease was an unfavorable factor associated with an increased risk of multiple organ damage, CNS damage, death, as well as prolonged renal replacement therapy and incomplete recovery of kidney function. Anuria is associated with a higher level of markers of inflammation, hemolysis, thrombosis) and a lower level of the C3 component of complement, as well as a longer duration of thrombocytopenia, which allows us to consider these indicators as predictors of the severity of tHUS. The development of acute kidney injury with anuria in patients with tHUS, according to most indicators, significantly worsens the prognosis of patients and is a factor in an unfavorable prognosis in patients with tHUS.
The Investigation of Vortex Motion in the YBCO Devices Manufactured Utilizing a Gaussian-shaped Optical Spot from a Continuous-wave Laser
Authors: JUKNA Arturas
Published: February 2023

The current report focuses on the analysis of the investigation results of the Abrikosov vortex motion in the YBa2Cu3O7-d (YBCO) device, which is a c-axis textured 0.3 ´ 50 ´ 100 µm3 (thickness ´ width ´ length) stripe of YBCO superconductor deposited on a LaAlO3 substrate. A laser beam focused in a Gaussian-shape optical spot of 5 mm in diameter modifies the stripe, initiating the oxygen out-diffusion and its uneven distribution in illuminated areas and in this way causing the appearance of a higher level of deoxygenation in the spot center and a lower level at its edges (slopes of weak superconductivity region). At temperatures below the temperature of the superconducting transition Tc, the current-self-produced magnetic field penetrates the optically modified area of the stripe in a form of Abrikosov magnetic vortices, and due to the current-self-produced Lorentz force, the vortices move toward their annihilation line resulting in energy dissipation. The vortices pinned on the slopes experience strong pinning and exert a magnetic drag force on moving vortices, which is confirmed by the stepped current-voltage dependences of the YBCO devices measured at temperatures 0.933·Tc £ T £ 0.958·Tc. Our results demonstrate the advantages of partially deoxygenated YBCO material for the development of superconducting electronic devices with electronic properties controlled by the motion of Abrikosov vortices at temperatures below Tc of the superconductor.
SRI Adoption through Innovative Alliance-Building: Learning from the SRI-LMB
Authors:   Leader, Regenerative Farming, RoundGlass Wellbeing Pvt. Ltd., Mohali, India, Mishra Abha ,   Former Director, ACISAI, AIT, Thailand
Published: February 2023

Given the challenges presented by climate change, water shortage, and land degradation, sustainable agriculture strategies that increase farming systems’ resilience are needed more than ever. This is especially true for sustaining rice production which is the staple food for hundreds of millions of people. Agroecology-based System of Rice Intensification (SRI) is seen as a way forward in transforming food and agriculture systems, especially for the smallholder farmers to build an inclusive, safe, sustainable and resilient society. The findings reported here are based on the engagement that the Asian Center of Innovation for Sustainable Agriculture Intensification (ACISAI), Asian Institute of Technology (AIT), Thailand had in the Lower Mekong River (LMB) basin countries (Cambodia, Laos, Thailand, and Vietnam) using a regional project commonly known as “SRI-LMB”. Using a local, national and regional innovation platform that was designed to systematize engagement and strengthen communication for fuelling innovation, more than 15 institutions were involved in the six-year-long farmers’ participatory action research (FPAR) trial located in the 33 districts of 11 provinces in the LMB. The SRI was used as an ‘entry point’ for such engagement-led-transition. Average yield along with factor productivity increased by more than 50% with a significant reduction in cultivation costs, energy use, and greenhouse gas emission. The purpose of this paper is to share results, and also to detail three key processes that led to innovations in different areas for better adoption: 1. the multi-stakeholder platforms used for action; 2. The FPAR that led to community development; the evidence-based policy and strategies that can support the sustainability of rural livelihoods.
The Major Challenges and Scope for Sustainable Agriculture Development in India
Authors:   ICAR-Indian Institute of Rice Research, Hyderabad, V Ravindra Babu , P Madhu Babu ,   ICAR-Indian Institute of Rice Research, Hyderabad, K Suman ,   ICAR-Indian Institute of Rice Research, Hyderabad, CN Neeraja ,   ICAR-Indian Institute of Rice Research, Hyderabad
Published: February 2023

Globally the demand for organic farming is increasing and farmers need to adopt novel technologies to resolve the challenges during the practicing of organic farming. Organic agriculture includes sustainability of agricultural production, supporting the rural economy, maintaining ecological and environmental strength within agricultural systems, and also establishing sustainable human health. Improving crop productivity and income of the farmers is to be based on soil health management, pest and disease control, and adapting novel marketing strategies. The utilization of farmyard manure, vermicompost, and biofertilizers in organic farming develops soil health and plant growth that can be benefited by farmers by increasing crop yield and ecosystem health. The application of biopesticide and biocultural agents for controlling pest and diseases on the crop in organic farming will enhance crop yield and also reduces environmental pollution. Organic farmers need to adapt novel marketing strategies to sell their farm produce and to get higher economic benefits. The food produced from sustainable farming increases the health of the human, soil, and environment.
Improvement of Local Speciality Rices as a Boon to Health, Wealth and Export Diversity: Case of Kalanamak Rice
Authors:   Participatory Rural Development Foundation (PRDF), 59 Canal Road, Shivpur – Shahbazganj, Gorakhpur 273014, India, Chakraborty Ram Chet , - Ravindra Kumar ,   Participatory Rural Development Foundation (PRDF), 59 Canal Road, Shivpur – Shahbazganj, Gorakhpur 273014, India, - Shiv Badan Mishra ,   Participatory Rural Development Foundation (PRDF), 59 Canal Road, Shivpur – Shahbazganj, Gorakhpur 273014, India, - Anjali Sahani ,   Participatory Rural Development Foundation (PRDF), 59 Canal Road, Shivpur – Shahbazganj, Gorakhpur 273014, India, Srivastava Ashok Kumar ,   Participatory Rural Development Foundation (PRDF), 59 Canal Road, Shivpur – Shahbazganj, Gorakhpur 273014, India
Published: February 2023

A blessing from Lord Buddha some 3,000 years ago, and now a heritage rice of Uttar Pradesh, India is valued for its aroma, taste and nutritive quality. Its cultivation declined from 50,000 ha to less than 2,000 ha and was at the verge of extinction. No attention was paid for improving Kalanamak and it survived as landrace due to the mercy of the farmers. PRDF collected, catalogued and conserved 250 accessions of Kalanamak, and the best one, through Pureline selection, was released in 2007 and notified in 2010 as KN 3. Mutation breeding using gamma rays and EMS gave many academically interesting mutants but no high yielding dwarfs. Hybridization of KN 3 with Swarna Sub1 and Improved Sambha Mahsuri yielded varieties like Bauna Kalanamak 101, Bauna Kalanamak 102 and Kalanamak with shorter duration and 50% higher yield, released and notified in years 2016, 2017 and 2019 respectively. Protocol for organic production with higher yield was developed and certification under PGS arranged. Kalanamak is sugar-free with 49 to 52% Glycemic Index, 11% protein, 3 times higher Iron and 4 times higher Zinc. It is unique rice to have Vitamin A in form of Beta Carotene. Kalanamak is backed by Geographical Indication and PPV and FRA, and selling at five times higher price of common rice tripling farmers’ income. Now exported to Singapore, Nepal and Dubai has opened door to prosperity and added diversity to Basmati for export. This success story can be repeated for other land rices of speciality status.
Policy Options for Scaling-Up SRI
Authors:   Additional Chief Secretary/Executive Director, ITPO, Ministry of Commerce and Industry,  Government of India, New Delhi, India, - Vibhu Nayar , VK Ravichandran ,   Part time Climate Smart Agriculture Specialist, FAO, Tamil Nadu, India.
Published: February 2023

The challenge of increasing food production, in the context vertical expansion through improved productivity per unit of land area under the situation of adapting to the changing climatic conditions that impose water scarcity and Green House Gases (GHG) emissions from the rice fields. Many research findings showed that SRI method outperforming in terms of yield and reduction in cost of cultivation along with several perceived ecosystem benefits. Finally, the researchers suggest for further promotion and scaling up of the SRI method in suitable regions of India is highly imperative. SRI is knowledge and experience-based method of rice production than input centric technology. The SRI method has been piloted in most of the countries and a section of farmers realized its full or partial potential but they are reluctant to spread their success with their fellow farmers. It is right time to undertake a few studies by the behavioural scientists to nudge this innovative method of SRI among farmers to the niche paddy growing areas. Grain yields reported from field experiments carried out in different parts of India showed yield increases ranging from 9.3% to 68% as compared with conventional practice. The Ministry of Agriculture that included SRI as part of the National Food Security Mission in 133 food-insecure districts. The research wing of SAU should evolve new or modify the available transplanters and weeders for the exclusive mechanization under SRI method. The beneficial effects of SRI like water-saving, use of less inputs and reaping higher benefits by SRI technology should be made aware among farmers through demonstration. The scaling up of SRI needs to be buoyed out by the joint efforts of State Agricultural University Researchers, ministry of Extension personnel’s, not for profit organizations with farmers. Upscaling of SRI strategy will help achieve national as well as household food-security. This paper clearly describes the role of every institutional responsibility in reaching the unreached.
Lotus Foods’ Experience Developing Value Chains for SRI Rice
Authors:   Co-founders and Co-CEOs, Lotus Foods, California, USA, Lee Ken , Levine Caryl ,   Co-founders and Co-CEOs, Lotus Foods, California, USA
Published: February 2023

Since 2008, Lotus Foods, a US-based importer of heirloom and pigmented rice produced on family farms, has been sourcing marketable surpluses of rice grown by farmers using System of Rice Intensification (SRI) practices. It presently sources SRI-grown rice in Cambodia, India, Indonesia, and Thailand. Lotus Foods’commitment is based on the recognition that SRI is a more efficient, environmentally responsible, and equitable way to grow rice, especially for smallholder producers. In the countries where it sources rice, it works with long-term business partners who aggregate the rice and process it for shipment, handling also certifications and quality control. In the US, Lotus Foods has the job of ensuring final quality, packaging, marketing, sales and distribution. While the company has increased the amount of SRI rice it imports over the past 10 years, it had expected to be importing a lot more. This is due to challenges on both the supply and demand side. This includes supply chain partners’ initial lack of experience in processing, business skills, and export, as well as access to credit and modern equipment. The price of Lotus Foods’ SRI rice in the marketplace is thus at the upper range due to premiums paid for organic and fair-trade certifications and supply chain inefficiencies. Nonetheless, pro-active outreach to educate American consumers and the food industry about the benefits of SRI has resonated with both and generated growing support for the company’s pioneering efforts to help “change how rice is grown around the world”.
ANGRAU’s Contribution to the State and National Rice Baskets
Authors:   Vice Chancellor, ANGRAU, Lam, Guntur, A Vishnuvardhan Reddy , L Prashanti ,   Director of Research ANGRAU, Guntur, A Subbirami Reddy ,   Director (Seeds) ANGRAU Guntur, G Raghunadh Reddy ,   Principal Scientist &Head CARP, ANGRAU, Guntur, PV Satyanarayana ,   Principal Scientist and Head, ARS, Ragolu, T Srinivas ,   Principal  Scientist (Rice) RARS, Maruteru, BNVSR Ravikumar ,   Principal Scientist Maruteru, LV Subba Rao ,   PS & Head, Crop Improvement, PI-AICRP on Rice, ICAR-IIRR Hyderabad
Published: February 2023

ANGRAU is a pioneer in rice research in India. It has the credit of releasing 123 rice varieties in 58 years of its inception which include 91 HYVs, 30 pure line varieties and 2 hybrids. ANGRAU has the credit of developing first BPH tolerant rice variety MTU 5249 (Vajram) way back in 1986. Developed two rice hybrids for first time in the country in 1993 – APHR1 and APHR 2. Out of 45 mha of rice area in India, ANGRAU rice varieties occupy 14 mha of area, producing 38 mt of production accounting for 33.15% of total rice production in India. By cultivating ANGRAU rice varieties, a revenue of Rs 62317 crores is generated annually in the form of returns accounting for 2.22 percent of India’s Agricultural GVA.
Spatial Products for Crop Monitoring and Sustainable Agriculture
Authors:   Geospatial and Big Data Sciences, (ICRISAT), Patancheru, India, - Murali Krishna Gumma
Published: February 2023

The spatial cropland products are of great importance in water and food security assessments, especially in India, which is home to nearly 1.4 billion people and 160 million hectares of net cropland area. In India, croplands account for about 90% of all human water use. Cropland extent, cropping intensity, crop watering methods and crop types are important factors that have a bearing on the quantity, quality and location of production. Currently, cropland products are produced using mainly coarse-resolution (250-1000 m) remote sensing data., our study was aimed at producing three distinct spatial products at 30m and 250m resolution that would be useful and needed to address food and water security challenges. The first of these, Product 1, was to assess irrigated versus rainfed croplands in India using Landsat 30 m data in GEE platform. The second, Product 2, was to map major crop types using MODIS 250 m data. The third, Product 3, to map cropping intensity (single, double and triple cropping) using MODIS 250 m data. For the kharif season (the main cropping season in India, Jun-Oct), 9 major crops (5 irrigated crops: rice, soybean, maize, sugarcane, cotton and 5 rainfed crops: pulses, rice, sorghum, millet, groundnut) were mapped. For the rabi season (post rainy season, Nov-Feb), 5 major crops (3 irrigated crops: rice, wheat, maize and 2 rainfed crops: chickpea, pulses) were mapped. The irrigated versus rainfed 30 m product showed an overall accuracy of 79.8% with the irrigated cropland class providing a producer’s accuracy of 79% and the rainfed cropland class 74%. The overall accuracy demonstrated by the cropping intensity product was 85.3% with producer’s accuracies of 88%, 85% and 67% for single, double, and triple cropping respectively. Crop types were mapped to accuracy levels ranging from 72% to 97%. A comparison of the crop type area statistics with national statistics explained 63-98% variability. The study highlights production of multiple cropland products to support food security studies using multiple satellite sensor big-data, and RF machine learning algorithm that were coded, processed and computed.
Scaling Up SCI: Social Capital-Centered Integrated Strategy for Enhancing Production with Equity and Climate Resilience
Authors:   Agriculture strategy specialist, Auckland, New Zealand, CM Wijayaratna
Published: February 2023

The major barriers associated with the scaling up of SCI, especially in the small farm sector, are interwoven. These include lack of proper coordination of activities of many farmers operating on small holdings, inadequate economic capacity & poor input-output services. Therefore, up-scaling efforts should not focus only on a single barrier or just on knowledge building and dissemination. Moreover, environmental degradation such as erosion and pollution are caused by the cumulative effects of non-point sources or the individual decisions by many small farmers. These cannot be effectively dealt with through point source control mechanisms. For example, unless these users are informed, motivated, and organized to collectively adopt conservation-based production, environmentally inappropriate decisions will continue to be made. Therefore, investing in Social Capital is beneficial for managing Natural Capital. FO-managed Collective Action, CA would capture economies of scale, initiate a commercialization process, and develop mutually beneficial partnerships with the private sector promoting small farmers to actively engage in market economy while maintaining equity. Hence, the paper explores the scope for enhancing resource use efficiency and overall production to ensure equitable food security and climate resilience through the combined effects of SCI and CA by farmers. Organized CA and an integrated approach can play a key role in widening SCI adoption through coordination and minimizing conflicts. In this context, the paper proposed an integrated strategy centered around social capital for enhancing production with equity and climate resilience.
DETERMİNATİON OF SOME VALIDATION INDICATORS OF HPLC METHOD FOR QUANTITATIVE ANALYSIS OF TRIAMCINOLONE IN "POLCORTOLONE" TAB-LETS
Authors:   Azerbaijan Medical University, Department of Pharmaceutical Chemistry, Baku, Azerbaijan, Suleymanov Tahir , Yusifova Jamila ,   Azerbaijan Medical University, Department of Pharmaceutical Chemistry, Baku, Azerbaijan, Balayeva Emilya ,   Azerbaijan Medical University, Department of Pharmaceutical Chemistry, Baku, Azerbaijan
Published: February 2023

The article presents the results of a study conducted to determine some validation indicators for the quanti-tative determination of HPLC of triamcinolone in “Polcortolone” tablets, such as correctness, accuracy, linearity and compatibility of the system. The studied method is characterized by high efficiency, stability and specifici-ty. The limits of the accuracy of the method vary from 98.77% to 100.53%; standard deviation of accuracy 0.128%, reliability interval ±0.135; linear indicator 0.05-0.4 mg / ml with density interval R2 = 0.998, linear re-gression function y = 20770.91x-187.12; The number of theoretical levels in the system was 8305, and the rela-tive remainder of the peak was 1.13. The proposed method has such indicators as correctness, accuracy, linearity and system compatibility and allows you to control the quality of the drug "Polcortolone" at the stages of production and sale.
INTRANASAL COMPARISION OF THERMOREVERSIBLE SALMON CALCITONIN GEL AND SPRAY FORM
Authors:   1Istinye University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Istanbul, Türkiye, Alparslan Levent
Published: February 2023

In the current study, we developed original thermoreversible nasal gel (solgel) formulations of salmon calci-tonin (sCT). The effects of solgel have been confront with histologically with the original intranasal spray in sep-tums of rabbits. Solgel form has ability for a reversible adequate fluidity in the temperature of nasal area in pH 3 and 4. The residence time of the solution, which turns into a gel form, may be longer. Analytical assay was validated to determine the amount of sCT. Histopathological findings of the mucous membranes from rabbit septums were examined by light microscope. Inflammatory cell infiltration in the lamina propria, increase in Goblet cells, decrease in cilia loss and epithelial layer thickness were enumerated. The statistical evaluation were calculated by Krusskal-Wallis test. In the electron microsco py tissue samples were examined and developed formulations were found better than commercial spray histologically. Solgels are formulated to become gels according to the temperature of nasal mucosa (32-34 °C). Content uniformity of each application dose was provided as 450 µg sCT in sprays. Nasal mucosa grading of the groups was evaluated and statistically the dif-ferences were significant (p<0.05). In each deformation group commercial spray had significant changes than our formulations. Also in electron microscop examination, commercial spray group had intense separation of respiratory epithelial cells and ciliary loss however developed formulations were normal. Solgel formulations were comfortable and easy to use. they may be a good alternative for intranasal administrations. Developed solgels were evaluated less harmful to nasal mucosa histologically.
STUDY AND ANALYSIS OF ORGANIC ACIDS OF ANNUAL FLEABANE
Authors:   National University of Pharmacy, Kharkiv,Ukraine, Golovach Alena , Kovalev Sergey ,   National University of Pharmacy, Kharkiv,Ukraine, Kovalev Vladimir ,   National University of Pharmacy, Kharkiv,Ukraine
Published: February 2023

In the 21st century, plants continue to remain a source of obtaining new biologically active substances, cre-ating prerequisites for the combination of creating new promising drugs of various directions of action. The aim of this work is to study the organic acids of the herb of the Annual fleabane (Erigeron annuus). For the first time, using the method of gas chromatography with mass spectrometry (GC/MS), an extract from the herb of the Erigeron annuus flora of Ukraine was investigated and analyzed for the presence of organ-ic acids. 14 organic acids were found in the studied raw materials, which creates the prerequisites for the use of raw materials in the medical, pharmaceutical, cosmetic, food and agricultural industries.
MEASUREMENT AND MODELING OF SILDENAFIL CITRATE SOLUBILITY IN THE MIXTURES OF CHOLINE CHLORIDE/PROPYLENE GLYCOL AND WATER AT VARIOUS TEMPERATURES
Authors:   1 Student Research Committee, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran 2Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran, Nemati Arshin , Moradi Milad ,   3 Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran 4Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran, Rahimpour Elaheh ,   2Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran, Jouyban Abolghasem ,   2Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Published: February 2023

In this study, a shake-flask method was employed to measure the equilibrium solubility of sildenafil citrate in the mixtures of a choline-based solvent and water at different temperatures. The obtained data were then correlated with several well-known co-solvency models (e.g. the van't Hoff, the Jouyban-Acree, the Jouyban-Acree-van't Hoff, the mixture response surface and the modified Wilson models) and their accuracy was inves-tigated using mean relative deviations of the back-calculated data. Furthermore, the apparent thermodynamic values for sildenafil citrate dissolution process containing entropy, enthalpy and Gibbs free energy were calcu-lated by applying the van’t Hoff and Gibbs equations.
ChatGPT and Big Data: Enhancing Text-to-Speech Conversion
Authors: Hatim Abdelhak Dida  , DSK Chakravarthy  , Fazle Rabbi
Published: February 2023

Converting text into voice (TTS) has many important uses in fields as diverse as accessibility, instruction, and recreation. As big data continues to expand at a dizzying rate, TTS conversion systems must adapt to new difficulties in terms of data amount and variety. To improve TTS conversion for huge data, we propose here to employ the cutting-edge language model ChatGPT. We begin with a brief history of text-to-speech (TTS) conversion and big data, before discussing the current state of TTS conversion technology and its limitations. We then go on to detail how ChatGPT was built and how it was taught to perform TTS conversion. We conclude by comparing the results of the ChatGPT-based TTS conversion system to those of existing TTS systems and analysing the results on a massive real-world big data dataset. Our experiments show that using ChatGPT improves the quality and efficiency of TTS conversion for huge data by a significant margin.
Large Scale Data Using K-Means
Authors: Raheela zaib  , OURLIS Ourabah
Published: February 2023

Because of the exponential growth of high-layered datasets, conventional database querying strategies are inadequate for extracting useful information, and analysts must now devise novel techniques to meet these demands. Such massive articulation data results in a plethora of new computational triggers as a result of both the rise in data protests and the increase of elements/ascribes. Preprocessing the data with a reliable dimensionality reduction method improves the efficacy and precision of mining operations on densely layered data. Therefore, we have compiled the opinions of numerous academics. Cluster analysis is a data analysis tool that has recently acquired prominence in a number of different disciplines. K-means, a common parceling-based clustering algorithm, looks for a fixed number of clusters that can be identified using only their centroids. However, the outcomes depend heavily on the starting points of the clusters' focuses. Again, there is a dramatic rise in the number of distance calculations with increasing data complexity. This is due to the fact that assembling a detailed model typically calls for a substantial and distributed amount of preliminary data. There may be a substantial time commitment involved in preparing a broad collection of ingredients. For huge data sets in particular, there is a cost/benefit analysis to consider when deciding how to create orders: speed vs. accuracy. The k-means method is commonly used to compress and sum vector data, as well as cluster it. For precautious k-means (ASB K-means), we present No Concurrent Specific Clumped K-means, a fast and memory-effective GPU-based method. Our method can be adjusted to use much less GPU RAM than the size of the full dataset, which is a significant improvement over earlier GPU-based k-means methods. Datasets that are too large to fit in RAM may be clustered. The approach uses a clustered architecture and applies the triangle disparity in each k-means focus to remove a data point if its enrollment task or cluster it belongs to remains unaltered, allowing it to efficiently handle big datasets. This reduces the number of data guides that must be transferred between the CPU's Slam and the GPU's global memory.
Between areolated and band-shaped spots: a revision of Lacronia Strand, 1942 (Opiliones, Gonyleptidae).
Authors: Carvalho Rafael N. , Kury Adriano B.
Published: February 2023

The genus Lacronia Strand, 1942 is herein revised, and a maximum parsimony phylogenetic analysis of morphological characters (30 taxa, 115 characters, 2962 scorings) is performed to test its monophyly. As a result, Lacronia is herein made monophyletic by means of the inclusion of Discocyrtus boraceae B. Soares, 1942, Discocyrtus niger Mello-Leitão, 1923 and Discocyrtus tenuis Roewer, 1917. Lacronia including those species is the sister group of Discocyrtus s. str. inside the DRMN-clade, and should be removed from Pachylinae Sørensen, 1884, although without a new subfamilial assignment for now. Four new junior subjective synonyms are detected for the first time (Discocyrtus rarus B. Soares, 1944 = Discocyrtus fazi Piza, 1942 = Discocyrtus niger Mello-Leitão, 1923; Discocyrtus infelix Mello-Leitão, 1940 = Discocyrtus nigrolineatus Mello-Leitão, 1923 = Discocyrtus tenuis Roewer, 1917). Accordingly, the following new combinations are proposed: Lacronia boraceae (B. Soares, 1942) comb. nov., Lacronia nigra (Mello-Leitão, 1923) comb. nov. and Lacronia tenuis (B. Soares, 1942) comb. nov. Lacronia is endemic to the Atlantic province of Brazil, with verified records from the states of Rio de Janeiro, Santa Catarina and São Paulo. As a geographic note, the record of ‘D. fazi’ for Chile is here discussed and considered incorrect.
МЕТА ТА ЗАВДАННЯ УПРАВЛІННЯ АКТИВАМИ В ЗАКЛАДАХ ОХОРОНИ ЗДОРОВ`Я
Authors:   Вінницький соціально-економічний інститут університету «Україна», Балахонова Олеся , Масленчук Микола ,   Вінницький соціально-економічний інститут університету «Україна»
Published: February 2023

Досліджено, що до активів закладів охорони здоров’я належать ресурси, які ними контролюються і повинні принести їм економічну вигоду шляхом використання в процесі надання нематеріальних послуг, при обміні на інші активи чи під час погашення зобов’язань установи. Необоротні активи – це матеріальні та нематеріальні ресурси, які належать установі та забезпечують її функціонування й строк корисної експлуатації яких, як очікується, становить більше одного року. До оборотних активів належать засоби, призначені для невиробничого споживання або використання в процесі господарської діяльності протягом одного року. Метою управління активами в закладах охорони здоров’я є: виявлення нестач, розтрат, крадіжок та інших порушень; попередження порушень; виявлення та мобілізація резервів; контроль за достовірністю даних фінансової звітності; вивчення причин та умов, що породжують безгосподарність та марнотратство; виявлення відповідності господарювання нормативам, положенням; виявлення та визначення суми збитку, нанесеного порушенням. Оцінка ефективності управління активами в закладах охорони здоров’я здійснюється за допомогою методів аналізу фінансово-економічного стану установи.
МЕТОДИ ТА ПРИНЦИПИ УПРАВЛІНСЬКИХ РІШЕНЬ В ІНВЕСТИЦІЙНІЙ ДІЯЛЬНОСТІ
Authors:   Вінницький соціально-економічний інститут університету «Україна», Балахонова Олеся , Павлюк Тетяна ,   Вінницький соціально-економічний інститут університету «Україна»
Published: February 2023

Досліджено, що в діяльності підприємства важлива роль приділяється методам та принципам прийняття управлінського рішення. Завдяки методам та принципам, які використовує керівник у прийнятті рішень, рішення краще приймаються. Наведено основні вимоги у процесі прийняття управлінських рішень, а саме: наукова обґрунтованість, цілеспрямованість, правомірність, оптимальність, своєчасність, системність, комплексність. Зазначено, що методи управлінських рішень – це послідовність певних управлінських операцій і різних процедур, які необхідно прийняти для вирішення проблеми підприємства. Досліджені методи управлінських рішень: постановки проблеми, виявлення способів вирішення проблеми, оцінки варіантів і вибір найкращого рішення, реалізації рішення, прогнозування, збору інформації, ключових запитань, інверсій, вільних асоціацій, морфологічного аналізу, номінальної групової техніки, Дельфі, мозкового штурму, конференції ідей, сценаріїв.
ОСНОВНІ ЗАВДАННЯ ТА ЕТАПИ ОРГАНІЗАЦІЇ ПРАЦІ НА ПІДПРИЄМСТВІ
Authors:   Вінницький соціально-економічний інститут університету «Україна», Балахонова Олеся , Паліга Анастасія ,   Вінницький соціально-економічний інститут університету «Україна»
Published: February 2023

У статті відмічено, що організація праці являється формою, у якій реалізуються економічні результати трудової діяльності. Наведено основні три види організаційної діяльності, а саме, організація праці, організація виробничо-торгівельної діяльності та організація управління. Виділено основні напрями організації праці, а саме, розподіл та взаємозв’язок праці, проектування трудових процесів, розподіл робочих місць, проектування систем обслуговування, режимів праці та відпочинку, створення сприятливих санітарно-гігієнічних, психологічних та соціальних умов праці, формування працездатних трудових колективів (зокрема відділів). Наведено основні групи завдань організації праці, а саме, техніко-технологічні, економічні, психофізіологічні, соціальні. Запропоновано основні елементи організації праці на підприємстві.
ВІКТИМНА ПОВЕДІНКА ЖЕРТВ ЗЛОЧИНІВ, МОДЕЛЬ ПОВЕДІНКИ ПОТЕНЦІЙНОЇ ЖЕРТВИ
Authors:   Вінницький соціально-економічний інститут університету «Україна», Плаксивий Олег , Олійник Олеся
Published: February 2023

Дане дослідження виявляє основні поведінкові особливості жертви, її емоційний стан та характеристики за якими її ідентифікує злочинець. Воно спрямоване на визначення ключових моментів, якими оперується злочинець під час вибору жертви, її психологічного портрету та причини її віктимної поведінки.
АНАЛІЗ ДІЯЛЬНОСТІ ПІДПРИЄМСТВ БУДІВЕЛЬНОЇ ГАЛУЗІ
Authors:   Вінницький торговельно-економічний інститут ДТЕУ, Лобачева Ірина , Китайчук Тетяна ,   Вінницький торговельно-економічний інститут ДТЕУ, Покиньчереда Віталій ,   Вінницький торговельно-економічний інститут ДТЕУ
Published: February 2023

У статті досліджено теоретико-методологічні аспекти аналізу діяльності будівельних підприємств. Спорудження будь-якої будівлі є досить масштабним і довгостроковим інвестиційним проектом, тому замовнику будівництва або його інвестору необхідний інструмент перманентного якісного моніторингу всіх процесів, як суто технічних і технологічних, так й обліково-аналітичних. Особливості аналізу будівельних підприємств обумовлені специфікою ціноутворення у цій галузі та обліку собівартості підготовчих й будівельних робіт, а також достатньо складною, як правило, багаторівневою системою розрахунків між учасниками процесу будівництва об'єкта нерухомості. Аналіз будівництва дозволяє здати об’єкт нерухомості вчасно і без зміни запланованої якості та перевищення встановленого бюджету. В умовах сьогодення для підприємства важливими питаннями є розширення мережі будівництва та зростання прибутковості основної діяльності.
Literasi Mitigasi Risiko dan Asuransi Perjalanan Wisata
Authors: Kurniawan Yohanes Jhony , Julianto Heppy , Suhartono
Published: February 2023

This Community Service Takes the Title of Risk Mitigation Literacy and Travel Insurance. This Community Service aims to produce PKM Outcome Materials that will be published in Premium journals or journals of community service and entrepreneurship, Risk Mitigation Literacy Materials and travel insurance made in, zoom recordings, and disseminate via YouTube, and Increase literacy to the public through Management Sharing Sessions, posters and expansion of the idea of ​​Risk Mitigation, Travel Insurance, and the importance of understanding the underwriting process in insurance coverage. The method of this research is Implementation Time. The implementation time of the activity is April - August 2022. In the form of designing Literacy Materials for Risk Mitigation and Travel Insurance, publishing the idea of ​​Risk Mitigation and Travel Insurance, and conducting literacy by holding Zoom meetings in Management Sharing Sessions activities underwriting process insurance coverage. The result of this Community Service is the availability of literacy materials, posters, literacy activities in the 7.08th Management Session.
Influence of the microbiome on the quality of human life
Authors: Stępień–Słodkowska Marta , Bolach Bartosz , Ryterská Karina , Kozubal Katarzyna , Bolach Eugeniusz
Published: February 2023

The World Health Organization defines human health as physical, mental and social well-being. However, the contemporary challenges of health care systems in the world, dedicated to various health problems, are more and more often characterized by a holistic approach to health. Therefore, they require many definitions of health in various aspects of maintaining health and the pursuit of health. Health is the physiologically correct functioning of systems and organs, and the ability to maintain it is an active process involving distinct adaptive mechanisms that coordinate interactions between the body's systems and organs. Homeostasis is the body's ability to maintain health and the proper functioning of the body in the face of changing external or internal factors. One is the human microbiome, which is made up of microbes that make up a biocenosis, which can vary from person to person. Various types of microflora inhabit the human skin, mouth, nose and intestines, playing a role in the immune system and human metabolism. The literature review shows the relationship between the human microbiome and nutritional needs, metabolic rate and other measures of health. Research in this direction will contribute to the identification of ways to modify lifestyle elements in order to prevent civilization diseases.
Perspektif Hukum Islam Tentang Hiburan Organ Tunggal (Keyboard)
Authors: Munthe Mahyudin
Published: February 2023

This research is an attempt to find out the basic habits of people in doing keyboard entertainment. The main questions to be answered through this research are: 1) What according to Islamic law regarding a single organ (keyboard)? 2) What are the effects of a single organ (keyboard)? This study aims to determine Islamic law regarding a single organ (keyboard) and to determine the impact that arises from a single organ (keyboard) on the surrounding community. To answer this question, this research uses a type of library research. From the research, the majority of people in carrying out keyboard entertainment is a habit that is often done by the community and based on a strong tradition. even though keyboard entertainment is not in accordance with Islamic teachings (haram). And as for the impact of a single organ (keyboard), namely the number of sins that arise such as drunkenness, displaying genitalia, disturbances, disturbing balance, making the center of courtship, even causing lives to be lost.Penelitian ini merupakan usaha untuk mengetahui dasar kebiasaan masyarakat dalam melakukan hiburan keyboard. Pertanyaan utama  yang ingin di jawab melalui penelitian ini adalah: 1) Bagaimana tinjauan hukum islam tentang organ tunggal (keyboard)? 2) apa saja dampak  yang di timbul kan organ tunggal (keyboard)? Penelitian ini mempunyai tujuan yaitu untuk mengetahui hukum Islam tentang organ tunggal (keyboard) dan untuk mengetahui dampak yang di timbulkan dari organ tunggal (keyboard) kepada masyarakat sekitar. Untuk menjawab pertanyaan tersebut, maka penelitian ini menggunakan jenis penelitian pustaka. Berdasarkan dari penelitian, mayoritas masyarakat dalam melaksanakan hiburan keyboard merupakan suatu kebiasaan yang sering di lakukan oleh masyarakat dan di jadikan sebagai tradisi yang kuat. padahal hiburan keyboard tidak sesuai dalam ajaran islam (haram). Dan adapun dampak organ tunggal (keyboard) yaitu banyaknya dosa  yang di timbulkan seperti mabukan, menampilkan aurat, perkelahian, mengganggu ketenangan tetangga, menjadikan pusat pacaran, bahkan sampai melakukan kerusuhan yang mengakibatkan nyawa melayang.
Money Laundering through Cryptocurrency and Its Arrangements in Money Laundering Act
Authors: Wardani Andhira , Ali Mahrus , Barkhuizen Jaco
Published: February 2023

The development of the modus operandi of money laundering become a major concern. Cryptocurrency technology has the potential to become a new media for money laundering because law enforcement officials still use to this technology, this technology which has a pseudonymous and even anonymous character is a new means for money laundering perpetrators to disguise their crimes. This study aims to examine how cryptocurrency is used as the modus operandi of money laundering and how is the readiness of regulations in Indonesia, especially Law No. 8 of 2010 in prosecuting money laundering offenders with the cryptocurrency modus operandi. This study uses a normative juridical method with legal materials from literature studies and uses a statutory regulation approach. The results of this study are the use of crypto as a mode of money laundering due to peer-to-peer networks, namely the absence of third parties to supervise crypto transactions, high user privacy, and transaction flexibility.

Abstrak. Berkembangnya modus operandi pencucian uang menjadi perhatian utama. Teknologi cryptocurrency berpotensi menjadi media baru TPPU dikarenakan masih awamnya teknologi tersebut oleh aparat penegak hukum, teknologi yang memiliki karakter pseudonymous bahkan anonymous ini menjadi sarana baru bagi pelaku TPPU untuk menyamarkan kejahatannya. Penelitian ini bertujuan untuk mengkaji bagaimana pemanfaatan cryptocurrency sebagai modus operandi TPPU dan bagaimana kesiapan regulasi di Indonesia khususnya Undang-Undang Nomor 8 Tahun 2010 dalam menjerat pelaku TPPU dengan modus operandi cryptocurrency. Penelitian ini menggunakan metode yuridis normatif dengan bahan hukum studi kepustakaan dan menggunakan pendekatan peraturan perundang-undangan. Hasil penelitian ini adalah pemanfaatan kripto sebagai modus pencucian uang dikarenakan jaringan peer-to-peer yaitu tidak adanya pihak ketiga yang melakukan pengawasan transaksi kripto, privasi pengguna yang tinggi, dan fleksibilitas transaksi.

Kata kunci: Modus Operandi, Cryptocurrency, Pencucian Uang, Indonesia
Open-pit time scale optimisation in a truck scheduling problem
Authors:   University of Mining and Geology “St. Ivan Rilski”, Asenovski Simeon , Kaikov Dimitar ,   University of Mining and Geology “St. Ivan Rilski”
Published: February 2023

In the present economic situation, the open-pit mining processes require flexible solutions for achieving the set goals. The aim of the study is to consider a comprehensive mathematical model for a short and long term open-pit mine optimisation in a truck scheduling problem. The model can be applied in different situations with various number of units and trajectories depending on the landscape of the area in question. Significant amount of parameters modulating the discussed processes is analysed.
Laboratory model of a magnetic levitation system
Authors:   University of Mining and Geology “St. Ivan Rilski”, Gorbounov Yassen , Peychinov Petar ,   University of Mining and Geology “St. Ivan Rilski”
Published: February 2023

The magnetic levitation consists of balancing the forces of attraction and repulsion of a ferromagnetic object located in a foreign magnetic field in such a way as to keep a desired distance between the object and the magnet. This technology is receiving increasing attention because it helps to eliminate the frictional losses due to the lack of mechanical contact. This makes it possible to reduce the wear of critical machine parts and achieve high speeds with increased positioning accuracy. Advanced applications include the high-speed Maglev trains, magnetic bearings and suspension, electromagnetic cranes, high-accuracy positioning of wafers in photolithography in the manufacturing of integrated circuits, and other high-precision contactless positioning devices. Positive results are also observed in applications from the mining and processing industry in the extraction and processing of raw materials, which makes the topic relevant. The paper presents a laboratory model of a single degree of freedom electromagnet-based system intended to aid the studying of the effect of magnetic levitation. The possibilities for the implementation of different positional feedback types are discussed together with the power circuit that drives the electromagnet. A mathematical model and implementation of a fully digital algorithm that uses the PID control law are presented. Experiments are conducted that could aid in building a sensorless control system. The elaborated laboratory model allows for easy upgrade and can be used in disciplines in the field of measurement, control, and automation as a whole.
Jet fans efficiency in tunnel emergency situations
Authors:   University of Mining and Geology “St. Ivan Rilski”, Kostadinova Nadezhda
Published: February 2023

Tunnel construction has become an important and growing activity. Tunnelling is an important part of transport infrastructure and is a part of the sustainable development of the country. The tunnel ventilation during construction and operation is part of the whole design procedure. Although ventilation might be performed with different approaches, longitudinal ventilation with jet fans is most often employed. The efficiency of such devices depends on several factors – design parameters, location in the tunnel, interaction with main current. The last one is crucial in emergency situations, especially during fires when both temperature and density of main current change. One important point in normal and emergency ventilation design is the downwind influence of jet fans. This paper presents a longitudinal scheme with jet fans. Based on energy and mass conservation, the interaction between the jet fan and the main current is considered, leading to expressions for areas of impact. Several models for fire temperature distribution downstream are presented, outcomes are compared and suggestions for use are made. Additionally, jet fan efficiency coefficients are adjusted due to modelling results.
CONTROL OF BLAST-INDUCED SEISMIC ACTION GENERATED BY TECHNOLOGICAL BLASTINGS
Authors:   University of Mining and Geology “St. Ivan Rilski”, Mollova Zdravka , Penev Vladimir ,   University of Mining and Geology “St. Ivan Rilski”
Published: February 2023

This article presents some of the studies on drilling and blasting technologies applied in the Assarel copper mine. The main emphasis is on examining the seismic effects on a particular engineering facility, located on the territory of the mine - CPT-3. The assessment of the blastinduced seismic loading on the structure is based on an analysis of the registered data on the site. Recommendations for the design of blasting parameters are provided.