bluuebunny/crossref_metadata_2025 huggingface dataset:
Sistem Informasi Pengecekan Data Barang Keluar dengan Barcode berbasis Android
Authors: Nadya Ayu , Tanti Lili
Published: June 2023

Besarnya kepuasan konsumen terhadap pelayanan suatu toko sangat dipengaruhi oleh persediaan barang dalam suatu kegiatan transaksi. Pada CV Abadi Amanah khususnya pada area sistem inventory dan verifikasi barang masuk dan keluar masih dilakukan secara manual dengan cara memeriksa setiap produk yang ada baik barang datang maupun barang keluar, sehingga jika mencari data akan terkendala dan memakan banyak waktu diperlukan sistem. dibangun dengan bantuan komputer sebagai alat untuk membantu dan mengatasi permasalahan yang ada. Teknologi informasi digunakan dalam sistem inventaris karena pencatatan inventaris berdampak signifikan pada bisnis dan memudahkan pelaporan inventaris di gudang untuk barang masuk dan keluar, yang mendukung pengambilan keputusan dan meningkatkan standar sistem saat ini. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana data barang yang ada dapat dikumpulkan secara cepat dan elektronik sehingga menghasilkan data dan informasi pergudangan yang akurat. Setelah itu akan dikembangkan sistem pendataan barang masuk dan keluar berbasis Android agar lebih efektif dan efisien dengan menggunakan teknologi barcode.
Implementasi Metode Cosine Similarity Dalam Mendeteksi Kemiripan Dan Perbedaan Gambar Hasil Scan Berbasis Android
Authors: Telaumbanua Kristiawan , Nababan Labuan
Published: June 2023

Umumnya orang-orang dapat menghasilkan sebuah gambar dari kamera, akan tetapi dapat juga melakukan scan terhadap gambar yang sudah di cetak sehingga mendapatkan hasil scan yang mirip dengan gambar asli. Masalah yang terjadi adalah terkadang munculnya keraguan akan gambar hasil scan apakah sudah mirip atau bagus hasilnya dan sesuai dengan gambar aslinya. Sehingga dari permasalahan tersebut diperlukan suatu konsep untuk mengetahui persentasi kesamaan pada sebuah gambar hasil scan sehingga dapat mengetahui keberhasilan untuk menyamakan gambar hasil scan dengan yang asli. Pada analisa ini penulis menggunakan metode CS perlu mendeteksi kesamaan dan perbedaan dari citra gambar hasil scan menggunakan android yang dibuat menggunakan platform eclipse juno. Gambar yang merupakan hasil scan diupload dari folder penyimpanan gambar kemudian dilakukan perhitungan dengan menerapkan metode Cosine Similarity menggunakan nilai RGB pada setiap pixel yang terdapat dalam gambar untuk mendapatkan hasil kemiripan dan perbedaan citra gambar. Sehingga dengan adanya implementasi metode Cosine Similarity dapat mendeteksi kemiripan dan perbedaan citra gambar dengan mudah.
Metode Single Exponential Smoothing untuk sistem informasi peramalan pengelolaan stok vaksin
Authors: Fadillah Nur , Fitrianto Rahmad Iwan
Published: June 2023

Vaksin adalah bahan yang dibuat dari bakteri atau virus suatu penyakit yang telah dilemahkan atau dilumpuhkan sedemikian rupa sehingga dengan sengaja dimasukkan ke dalam tubuh seseorang untuk merangsang tubuh orang tersebut menghasilkan zat anti penyakit. Seperti pandemi saat ini, dimana vaksin merupakan hal yang sangat penting yang dibutuhkan dan diprioritaskan oleh pemerintah dalam menghadapi pandemi yang juga menjadi perhatian banyak negara saat ini. Salah satu penerima manfaat dari pengelolaan stok vaksin adalah Puskesmas Sentosa yang mencatat pemakaian vaksin setiap hari dan melaporkan hasil pemakaiannya setiap bulan. Di Puskesmas Sentosa Baru permasalahannya proses pendaftaran pengurusan penggunaan vaksin saat ini masih dilakukan dengan pembukuan dan pemakaian bulanan dengan menggunakan microsoft excel. Karena vaksin merupakan barang yang memiliki nilai jual, pencatatan stok masuk dan stok keluar. harus benar mencocokkan data gudang keluar antara pengelola stok vaksin Puskesmas Sentosa Baru dengan data yang tercatat oleh penyedia layanan vaksin yang tidak sesuai dengan aturan provinsi.
Penerapan Metode Teorema Bayes dan Certainty Factor Untuk Menentukan Penyakit Mers, Sars dan Covid 19
Authors: Jelita Oktaviani Putri , Meizar Abdul
Published: June 2023

SARS, MERS dan COVID-19 adalah penyakit pernapasan yang disebabkan oleh keluarga virus yang sama. Ketiga penyakit tersebut merupakan infeksi pernapasan akibat virus yang dapat menyebabkan kematian. Ketiga penyakit tersebut memiliki gejala yang mirip dan membutuhkan penanganan yang tepat untuk mencegah efek samping lebih lanjut, serta akses terhadap layanan kesehatan yang semakin sulit pada masa pandemi, sehingga dapat menunda diagnosis awal ketiga penyakit tersebut. Sistem pakar yang dikembangkan dapat berfungsi sebagai alat bantu diagnosa untuk mengidentifikasi potensi infeksi saluran pernapasan dan memberikan solusi yang paling tepat. Sistem Pakar untuk Diagnosis Infeksi Saluran Pernapasan dapat digunakan untuk mendukung para profesional yang menyelidiki infeksi saluran pernapasan. Sistem pakar yang dikembangkan untuk diagnosis infeksi saluran pernapasan ini menggunakan Teorama Bayes dan Certainty Factor. Oleh karena itu, dengan adanya penelitian ini, peneliti merekomendasikan pengembangan aplikasi sistem pakar yang bertujuan untuk mengurangi kecemasan pasien dengan gejala-gejala tersebut. Solusi dari permasalahan tersebut adalah dengan membuat sistem pakar yang dapat mendiagnosa penyakit infeksi saluran pernafasan dengan menggunakan Teorama Bayes dan Certainty Factor, sehingga dapat dilakukan pencegahan sedini mungkin.
Rancang Bangun Sistem Informasi UMKM Di Tebing Tinggi Berbasis Web
Authors: Hasanah Nur , Triandi Budi
Published: June 2023

Penggunaan dan penyelenggaraan sistem informasi yang efektif harus mendukung sistem informasi Usaha Mikro Kecil dan Menengah (UMKM) Kota Tebing Tinggi. Alhasil, diharapkan para pelaku usaha mampu menerapkan rencana operasional yang efektif yang didukung oleh pemanfaatan teknologi informasi. Salah satu UMKM yang lebih canggih yang menawarkan informasi tentang UMKM lainnya yang terintegrasi satu sama lain adalah industri perdagangan. UMKM di Kota Tebing Tinggi berjuang dengan kurangnya pengetahuan tentang keberadaan mereka dan populasi besar yang tidak mengetahui keberadaan mereka. Oleh karena itu, tujuan dari proyek ini adalah untuk mengembangkan sistem informasi UMKM secara online. Sistem ini dibuat oleh para ilmuwan menggunakan metodologi air terjun. menyelesaikan pengembangan sistem sesuai dengan kebutuhan pengguna. Sistem informasi UMKM ini memungkinkan untuk menyusun dan memantau dengan benar semua operasi dan keberadaan pengusaha UMKM.
Mendeteksi Persamaan Gambar Citra Digital Dengan Menggunakan Metode Levensthein Distance
Authors: Noval Pradana Yoga , Ayoe Elhias NST Mas
Published: June 2023

Orang yang mencurigai gambar yang diedit harus membandingkannya dengan gambar aslinya karena perangkat lunak pengedit gambar memungkinkan untuk ditiru. Masalahnya adalah mereka yang menyamakan kesamaan gambar tidak dapat memberikan persentase kesamaan dengan spesifik. Deteksi kesamaan gambar dapat menghasilkan persentase kesamaan dengan rinci. Algoritma levenshtein distance memperbandingkan dua kata yang kemudian diukur berdasarkan berdasarkan kata masing-masing yang kemudian dihitung dengan menggunakan matrik yang dibangun dengan baris dan kolom dapat digambarkan dengan n dan m yang berisi kata per karakter masing-masing. Memakai fungsi yang mengembalikkan nilai 0 jika karakter yang dicocokkan sama dan sebaliknya memberikan nilai 1 jika karakter yang dicocokkan tidak sama.Dengan adanya aplikasi deteksi kesamaan gambar berdasarkan citra digital gambar menggunakan metode levensthein distance maka deteksi kesamaan gambar dapat menghasilkan persentase kesamaan dengan rinci.Sebaiknya aplikasi yang telah dibuat sebaiknya dapat menggunakan dua metode sehingga dapat mengetahui hasil dari dua metode.
Pendekatan Fault Tree Analysis Pada Keselamatan Kerja Sebagai Usaha Meningkatkan Produktivitas Kerja di PT. XYZ
Authors: Prastio Fikri , Ismail
Published: June 2023

PT. XYZ merupakan sebuah perusahaan jasa konstruksi masalah yang terjadi adalah dalam pengoperasiannya sangat rentan akan kecelakaan seperti kaki atau kepala yang tertimpa benda berat, luka bakar, tangan luka sobek karena mesin dan benda, iritasi pada mata akibat pengelasan atau penggrendahan yang dapat mengakibatkan kecelakaan yang mengakibatkan menurunnya tingkat produktivitas kerja. Pada PT. XYZ belum adanya analisis kecelakaan kerja sehingga tidak diketahui akar dari penyebab kecelakaan kerja dengan ini penulis menggunakan metode Fault Tree Analysis (FTA) sehingga analisis kecelakaan kerja dengan menggunakan metode ini dapat diketahui akar dari penyebab kecelakaan kerja. Dalam analisis ini Dapat diketahui pengaruh tingkat kecelakaan kerja terhadap produktivitas Terlihat bahwa semakin sedikit kecelakaan yang terjadi, maka semakin kecil pula hari kerja yang hilang dan mengakibatkan semakin tingginya tingkat produktivitas kerjanya dengan adanya peningkatan produktivitas kerja maka akan mendapatkan keuntungan baik bagi perusahaan maupun karyawan dan diketahui bahwa nilai produktivitas pada tahun 2019 sebesar 0,9899, pada tahun 2020 sebesar 0,9934, dan pada tahun 2021 0,9958.
Evaluasi Postur Kerja Menggunakan Metode RULA Pada Aktivitas Bongkar Muat di CV. Karyatama Perintis Fajar
Authors: Dicky Dicky Alfiansyah , Marikena Nita
Published: June 2023

Satu di antara proses logistik yang utama adalah kegiatan proses bongkar muat ( manual material handling ), Proses manual material handling pada aktivitas bongkar muat terbagi atas 2 proses yaitu proses bongkar barang dan proses muat barang. Pada penelitian ini difokuskan pada proses bongkar barang sebaliknya. Aktivitas ini rentan terhadap terjadi nya cidera pada pekerja.  beresiko pada  muskuloskeletal yang biasa disebut dengan musculoskeletal disorders (MSDs) Tujuan penelitian ini untuk mengidentifikasi dan mengevaluasi postur kerja akibat dari aktvitas bongkar barang Metode yang digunakan adalah RULA (Rapid Upper Limb Assessment), menilai postur, gerakan dan gaya pada aktivitas kerja berdasarkan penilaian dari RULA untuk gangguan pada anggota tubuh bagian atas yaitu postur (pergelangan tangan, lengan atas, lengan bawah, perputaran pergelangan tangan, posisi kaki, leher dan punggung) setelah itu menentukan level resiko berdasarkan hasil dari skor akhir bahwa postur tubuh tersebut diperlukan perbaikan atau tidak. Hasil dari perhitungan dengan metode RULA diperoleh bahwa pekerja untuk postur tubuh memiliki nilai 4 pada penilaian skor akhir maka dari itu dalam katagori level resiko 2 yang menunjukan adanya penyelidikan dan perbaikan dibutuhkan. Hal tersebut dipengaruhi oleh postur tubuh yang tidak ergonomis (membungkuk dan menahan beban yang berat ). Kesimpulan dari hasil penelitian ini ialah postur kerja MMH pada CV. Karyatama Perintis Fajar diperlukan adanya penyelidikan dan perbaikan dibutuhkan. Saran yang dapat penulis berikan yaitu mengadakan evaluasi metode dan sistem kerja dan perancangan fasilitas kerja.
Penerapan Material Requirement Planning Pada Perencanaan Kebutuhan Bahan Baku Terhadap Produk Springbed di CV.VWX
Authors: Riza Muhammad , Marwan
Published: June 2023

Penerapan Material Requirement Planning pada perencanaan kebutuhan bahan baku terhadap produk springbed di CV. VWX di penelitian ini bertujuan untuk (1) mengetahui permintaan produk springbed dengan menggunakan peramalan, (2) mengetahui kapasitas maksimal setiap pemesanan bahan baku dalam sekali pesan, serta (3) mengetahui jumlah pemesanan bahan baku springbed. Teknik pengumpulan data pada penelitian ini menggunakan data primer dan data sekunder. Adapun hasil dari penelitian yaitu (1) hasil peramalan permintaan produk springbed pada periode berikutnya pada Maret 2023 per 2 bulan sebesar 1125 unit dengan MAPE (Mean Absolute Percent Error) sebesar 0,11, (2) pada satu kali pemesanan bahan baku periode berikutnya pada bulan Maret 2022 sebesar 5625 meter kain, 13500 kg busa, 28125 buah penjepit peer, 1740 pcs kawat kumparan, 1740 pcs slicon dan 56250 Pcs ram peer, dan (3) terdapat 12 kali frekuensi pemesanan bahan baku pembuatan springbed dengan biaya pemesanan Rp 2.400,00 lebih kecil dibandingkan metode perusahaan dengan frekuensi pemesanan sebanyak 48 kali sebesar Rp, 18.000,00
Interaction of Lipase with Lipid Model Systems
Authors: Zaitsev Sergei Yu. , Zaitsev Ilia S. , Milaeva Irina V.
Published: June 2023

The aim of this work was to study the interaction of lipases (as an important biopolymer) with models of biomembranes based on the phospholipid and cholesterol. Lipases (triacylglycerolacyl hydrolases) are widely distributed enzymes and well-known by their hydrolytic activity. The study of the lipase interactions with lipid vesicles in aqueous dispersions is of fundamental and practical interest. The pure phosphatidylcholine from egg yolk (ePC) and cholesterol (Chol) were obtained from Sigma-Aldrich. Lipase was obtained from hog pancreas. Measurements of the current and equilibrium surface tension (ST and eST) values were carried out using a BPA-1P device and ADSA program. The particle sizes in the prepared colloidal solutions were determined by the method of dynamic light scattering. An addition of lipase led to some decrease both, of ST and eST for the samples of ePC:Chol (in the ratios from19:1 to 1:1). The mean particle diameter (MPD) and effective particle diameter (EPD) values for the samples of ePC:Chol changed drastically by lipase addition. The EPD/MPD ratios increased from 1.7 to 2.0, from 1.8 to 2.6, from 2.3 to 6.5, from 1.5 to 2.9 for the samples of ePC:Chol at the ratios of 19:1, 14:1, 9:1, 7:1, respectively by lipase concentration increase. This general tendency can be explained by strong interaction of lipase with lipid membrane that leads to the formation of the mixed particles ePC:Chol:lipase with more narrow particle size distribution as compared to the initial EPD/MPD ratio (for the ePC:Chol mixture without lipase).
Real-World Implementation of Best-Evidence Cancer Distress Management: Truly Comprehensive Cancer Care
Authors: Ehlers Shawna L. , Gudenkauf Lisa M. , Kacel Elizabeth L. , Hanna Sherrie M. , Sinicrope Pam S. , Patten Christi A. , Morrison Eleshia L. , Snuggerud Jill , Bevis Danielle , Kirsch Janae L. , Staab Jeffrey P. , Price Katharine A.R. , Wahner-Hendrickson Andrea E. , Ruddy Kathryn J.
Published: June 2023

Background: Cancer distress management is an evidence-based component of comprehensive cancer care. Group-delivered cognitive behavioral therapy for cancer distress (CBT-C) is the first distress treatment associated with replicated survival advantages in randomized clinical trials. Despite research supporting patient satisfaction, improved outcomes, and reduced costs, CBT-C has not been tested sufficiently within billable clinical settings, profoundly reducing patient access to best-evidence care. This study aimed to adapt and implement manualized CBT-C as a billable clinical service. Patients and Methods: A stakeholder-engaged, mixed-methods, hybrid implementation study design was used, and the study was conducted in 3 phases: (1) stakeholder engagement and adaptation of CBT-C delivery, (2) patient and therapist user testing and adaptation of CBT-C content, and (3) implementation of practice-adapted CBT-C as a billable clinical service focused on evaluation of reach, acceptability, and feasibility across stakeholder perspectives. Results: A total of 40 individuals and 7 interdisciplinary group stakeholders collectively identified 7 primary barriers (eg, number of sessions, workflow concerns, patient geographic distance from center) and 9 facilitators (eg, favorable financial model, emergence of oncology champions). CBT-C adaptations made before implementation included expanding eligibility criteria beyond breast cancer, reducing number of sessions to 5 (10 total hours), eliminating and adding content, and revising language and images. During implementation, 252 patients were eligible; 100 (40%) enrolled in CBT-C (99% covered by insurance). The primary reason for declining enrollment was geographic distance. Of enrollees, 60 (60%) consented to research participation (75% women; 92% white). All research participants completed at least 60% of content (6 of 10 hours), with 98% reporting they would recommend CBT-C to family and friends. Conclusions: CBT-C implementation as a billable clinical service was acceptable and feasible across cancer care stakeholder measures. Future research is needed to replicate acceptability and feasibility results in more diverse patient groups, test effectiveness in clinical settings, and reduce barriers to access via remote delivery platforms.
Predicting All-Cause Mortality in Women With and Without Breast Cancer Using the Schonberg Index: A Women’s Health Initiative Study
Authors: Nelson Rebecca A. , Soto-Perez-de-Celis Enrique , Chlebowski Rowan T. , Schonberg Mara , Mortimer Joanne , Pan Kathy , Hou Lifang , Neuhouser Marian L. , Reding Kerryn W. , Saquib Nazmus , Wactawski-Wende Jean , Wolfson Emily , Sedrak Mina S. , Kruper Laura
Published: June 2023

Background: When treating older women with breast cancer, life expectancy is an important consideration. ASCO recommends calculating 10-year mortality probabilities to inform treatment decisions. One useful tool is the Schonberg index, which predicts risk-based all-cause 10-year mortality. We investigated the use of this index in women aged ≥65 years with breast cancer in the Women’s Health Initiative (WHI). Methods: We calculated 10-year mortality risk scores for 2,549 WHI participants with breast cancer (“cases”) and 2,549 age-matched breast cancer–free participants (“controls”) using Schonberg index risk scoring. Risk scores were grouped into quintiles for comparisons. Risk-stratified observed mortality rates and 95% confidence intervals were compared across cases and controls. Observed 10-year mortality rates in cases and controls were also compared with Schonberg index–based predicted 10-year mortality rates. Results: Compared with controls, cases were more often white (P=.005), had higher income and education levels (P<.001 for both), more often lived with their husband/partner (P<.001), scored higher on subjective health/happiness (P<.001), and needed less assistance in activities of daily living (P<.001). Participants with breast cancer had similar risk-stratified 10-year mortality rates compared with controls (34% vs 33%, respectively). Stratified results showed that cases had slightly higher mortality rates than controls in the lowest risk quintile and lower mortality rates in the 2 highest risk quintiles. Observed mortality rates in cases and controls were similar to Schonberg index–predicted mortality, with model c-indexes of 0.71 and 0.76, respectively. Conclusions: Among women aged ≥65 years with incident breast cancer, the Schonberg index–based risk-stratified 10-year mortality rates were similar to those in women without breast cancer, demonstrating a similar performance of the index among both populations. Along with other health measures, prognostic indexes can help predict survival among older women with breast cancer and support geriatric oncology guidelines that promote using life expectancy calculation tools for shared decision-making.
Las tecnologías digitales en un contexto de escasez de recursos: análisis de la competencia digital del profesorado de español en Benín
Authors: Legba Sètongnon Mélaine Prisca
Published: June 2023

With the advent of COVID-19, the world faced a number of challenges, including the continuity of education despite the closure of training centers and schools. As a solution, several countries in a situation of scarce resources have been forced to introduce digital technologies in their teaching practice, requiring teachers to be proficient in their use. The aim of this research is to analyse whether teachers of Spanish as a second language in Benin (Africa) are digitally competent to be able to introduce these technologies in their classes and to take stock of the technology at their disposal in order to be able to offer a proposal for improvement adapted to their needs. In order to do this, we have used a mixed methodology in which we have used information gathering techniques such as questionnaires and interviews with a sample of 85 Spanish teachers. Among the main results we can highlight the low knowledge of digital tools and in general a low level of digital competence. In the context analysed, a comprehensive proposal for improvement is needed, ranging from teacher training to a better provision of digital resources.

Con la llegada del COVID-19, el mundo se enfrentó a varios desafíos, incluida la continuidad de la educación a pesar del cierre de centros de formación y escuelas. Como solución, varios países que se encuentran en una situación de escasez de recursos se han visto abocados a introducir las tecnologías digitales en su práctica docente siendo necesario que el profesorado dominara el uso de las mismas. El objetivo de esta investigación es analizar si los profesores de español como segunda lengua en Benín (África) son competentes digitalmente para poder introducir estas tecnologías en sus clases y hacer un balance de la tecnología a su disposición para poder ofrecer una propuesta de mejora adaptad a sus necesidades. Para ello hemos empleado una metodología mixta en la que se han utilizado técnicas de recogida de información como el cuestionario y la entrevista contando con una muestra de 85 profesores de español. Entre los resultados principales podemos destacar el bajo conocimiento de las herramientas digitales y en general un bajo nivel de competencia digital. En el contexto analizado se hace necesaria una propuesta integral de mejora que vaya desde la formación del profesorado a una mejor dotación de recursos digitales.
The cation channel mechanisms of subthreshold inward depolarizing currents in the VTA dopaminergic neurons and their roles in the depression-like behavior
Authors: Wang Jing , Su Min , Zhang Dongmei , Zhang Ludi , Niu Chenxu , Li Chaoyi , You Shuangzhu , Sang Yuqi , Zhang Yongxue , Du Xiaona , Zhang Hailin
Published: June 2023

The slow-intrinsic-pacemaker dopaminergic (DA) neurons originating in the ventral tegmental area (VTA) is implicated in various mood- and emotion-related disorders, such as anxiety, fear, stress and depression. Abnormal activity of projection-specific VTA DA neurons is the key factor in the development of these disorders. Here, we describe the crucial role for the NALCN and TRPC6, non-selective cation channels in mediating the subthreshold inward depolarizing current and driving the firing of action potentials of VTA DA neurons in physiological condition. Otherwise, we demonstrate that downregulation of TRPC6 protein expression in the VTA DA neurons likely contributes to the reduced activity of projection-specific VTA DA neuron in CMUS depressive mice. Furthermore, selective knockdown of TRPC6 channels in the VTA DA neurons conferred mice with depression-like behavior. This current study suggests down-regulation of TRPC6 expression/function is involved in reduced VTA DA neuron firing and depression-like behavior in the mouse models of depression.
On evidentiality in American Spanish and Brazilian Portuguese
Authors: Martínez Vera Gabriel
Published: June 2023

This paper discusses the indirect evidential markers dizque in American Spanish and Brazilian Portuguese by focusing on the Spanish varieties of Guayaquil (Ecuador) and Lima (Peru), and the Brazilian Portuguese variety of São Paulo (Brazil). I adopt a comparative approach in which I discuss their syntax and semantics. To thoroughly document their properties in a theoretically driven approach, a comprehensive questionnaire building on previous literature was used, and data from five consultants per variety were gathered— fieldwork practices were followed. The purpose of such an approach is to complement previous studies, which have mainly focused on corpora. As for the syntactic properties, I discuss their distribution in connection to a number of different elements, such as modal and evidential adverbs, among many others; the use as an illocutionary evidential is, in general, disallowed in these varieties. As for the semantic properties, I discuss the types of evidence with which these evidentials are compatible, the at-issue vs. not-at-issue distinction and the doubt implication that sentences with these elements normally have. This study attempts to provide a comprehensive overview of these evidentials in these varieties, so that future research can build on it to single out different properties in controlled (e.g., experimental) settings.
A multi-class classification algorithm based on hematoxylin-eosin staining for neoadjuvant therapy in rectal cancer: a retrospective study
Authors: Wu Yihan , Liu Xiaohua , Liu Fang , Li Yi , Xiong Xiaomin , Sun Hao , Lin Bo , Li Yu , Xu Bo
Published: June 2023

Neoadjuvant therapy (NAT) is a major treatment option for locally advanced rectal cancer. With recent advancement of machine/deep learning algorithms, predicting the treatment response of NAT has become possible using radiological and/or pathological images. However, programs reported thus far are limited to binary classifications, and they can only distinguish the pathological complete response (pCR). In the clinical setting, the pathological NAT responses are classified as four classes: (TRG0-3), with 0 as pCR, 1 as moderate response, 2 as minimal response and 3 as poor response. Therefore, the actual clinical need for risk stratification remains unmet. By using ResNet (Residual Neural Network), we developed a multi-class classifier based on Hematoxylin-Eosin (HE) images to divide the response to three groups (TRG0, TRG1/2, and TRG3). Overall, the model achieved the AUC 0.97 at 40× magnification and AUC 0.89 at 10× magnification. For TRG0, the model under 40× magnification achieved a precision of 0.67, a sensitivity of 0.67, and a specificity of 0.95. For TRG1/2, a precision of 0.92, a sensitivity of 0.86, and a specificity of 0.89 were achieved. For TRG3, the model obtained a precision of 0.71, a sensitivity of 0.83, and a specificity of 0.88. To find the relationship between the treatment response and pathological images, we constructed a visual heat map of tiles using Class Activation Mapping (CAM). Notably, we found that tumor nuclei and tumor-infiltrating lymphocytes appeared to be potential features of the algorithm. Taken together, this multi-class classifier represents the first of its kind to predict different NAT responses in rectal cancer.
Desacatos de la mirada, lecturas en torno a imágenes y colectivos en la revuelta chilena de 2019
Authors: Veraguas Caripan Ignacio , Astorga Espinosa Amanda
Published: June 2023

No presenta resumen
Reseñas: Des/aparecer de Paula Anguita. La exposición el ciclo del carbono de Cristian Silva
Authors: Busch Verni Eva , Reynolds Olivia
Published: June 2023

No presenta resumen
Complicidad por omisión: análisis doctrinal y propuesta
Authors: Bustos Cárdenas Alejandra Elisabet
Published: June 2023

La relegación de la complicidad por omisión al alero de la figura del autor, dada principalmente por la comprensión de las funciones que cumple la posición de garantía, es el resultado derivado del habitual tratamiento que la doctrina propone en esta materia. Ello ha traído consigo que no sea posible apreciar claramente cuáles son las características de una eventual participación omisiva y que en muchos casos la presencia de la posición de garante descarte automáticamente toda forma de intervención que no sea la autoría. El objetivo de este trabajo es hacer una recopilación de dichas circunstancias y concebir una concepción de cómplice por omisión con características de garante. Lo anterior, se logra mediante la aplicación del reconocido sinalagma libertad/responsabilidad sumada a la unificación de criterios doctrinales dispersos en la literatura los que, aplicados de una manera ordenada y sistemática, pueden ser de utilidad a la praxis jurídica.
Brazilian autocratic infra-legalism: a response to Kim Lane Scheppele
Authors: Marina Slhessarenko Fraife Barreto
Published: June 2023

Kim Lane Scheppele claims that “autocratic legalism” is a new form of political authoritarianism, characterized by the use of laws and constitutional engineering. I argue that the Brazilian case provides two counterarguments to this thesis, first refuting the idea that lessons learned from past authoritarianism do not involve the use of law for non-democratic purposes, and then arguing that there are other legal instruments suitable for the implementation of political authoritarianism besides constitutions and laws. To this end, I divide the article into five parts. First, I sketch the theoretical approach and methodology. Second, I consider a broader literature on the significance of law in non-democratic regimes. Next, I report the importance of the use of law in the Brazilian military dictatorship (1964-1985). Fourth, I explain the use of administrative legal tools in contemporary Brazil and how this use evidences the existence of an “autocratic infra-legalism.” Finally, I present some concluding remarks, and a postscript written in the light of the presidential elections of 2022.
Militarismo, racismo y sensibilidades bárbaras: sociogénesis del autoritarismo de control social y punitivo en el Cono Sur
Authors: Bogo Chies Luiz Antônio
Published: June 2023

Se analizan el militarismo, el racismo y las sensibilidades bárbaras como peculiaridades socioculturales que, producto de procesos sociales de larga duración en el Cono Sur de América Latina, inciden en características y claves de interpretación de los sistemas de control social y castigo que se encuentran en la actualidad. Se trata de uma investigación exploratoria com base bibliográfica, referenciada em la sociología procesual de Norbert Elias. Sus resultados contribuyen tanto a resaltar elementos de amalgamas autoritarias y microdespotismos sociales, como a la elaboración de una agenda de investigaciones em el campo de la Sociología Histórica de la Pena.
Recuperando el rol de la mujer y la familia en la unión del Chacha-Warmi en la cultura aymara del altiplano peruano desde la perspectiva del Derecho de Género
Authors: Espinoza Coila Michael , Casazola Ccama Juan , Ccari Churquipa Ana Mercedes , Casazola León Johnn Adrian , Rojas Bellido Kelly Cindy , Chambi Ochoa Yaneth Soledad
Published: June 2023

Los grandes esfuerzos de la resistencia intelectual, así como su capacidad de incidencia en la teoría y funciones del Derecho, en las reformas legales que se ven opacadas en su implementación práctica por parte de los Estados, ocultaron la realidad de la marginación de las mujeres. Propiciaron una desigualdad que instaló a la mujer en una situación donde se incrementó su vulnerabilidad, y los Estados no han logrado establecer medios efectivos que permitan prevenir, investigar, sancionar acciones que contravengan con el respeto de los derechos que emanan en la legislación peruana. Este problema se ha ido asentando en nuestra realidad, ya desde épocas pasadas, siendo relativamente una postura heredada a partir de nuestra herencia occidental, quienes por la gran influencia que mantenían de la religión, posturas filosóficas antropocentristas y una crianza patriarcal, lograron expandir esta ideología hasta los años ochenta donde se dio una revolución doctrinal que ocasionó diversos cambios en la sociedad, por ende, en las normas y el Estado. Como resultado, consideramos que el Perú, usando su potestad normativa, está intentado mejorar la situación de desprotección a la mujer. Empero concluimos que es necesario conseguir la convergencia de una pluralidad de culturas, en las que se resalta la forma en como se ha desarrollado el matrimonio, siendo la concepción del Chacha-warmi una manifestación de la cultura aymara y andina, en donde, por la aplicación de los principios que caracterizan su cosmovisión cultural, pueden servirnos para revalorar el rol de la mujer tanto en su desempeño en la familia y en la sociedad.
Sosyal Bilgiler Öğretmenliği Lisans Programı Nasıl Olmalı? Öğretmenlerin Deneyimleri, Görüşleri ve Önerileri
Authors: YILMAZ Cevdet , KARADAĞ Yıldıray , BAYRAM Fatma Özge
Published: June 2023

Bu araştırmada Sosyal Bilgiler öğretmenlerinin Sosyal Bilgiler lisans programına ilişkin deneyim, görüş ve önerileri incelenmiştir. Araştırmada temel nitel araştırma yöntemi kullanılmıştır. Katılımcı grubunun belirlenmesinde ölçüt örnekleme yöntemi kullanılmış ve ölçütleri sağlayan 14 Sosyal Bilgiler öğretmeniyle araştırma yürütülmüştür. Veri toplama aracı olarak araştırmacılar tarafından geliştirilen standartlaştırılmış açık-uçlu mülakat formu kullanılmış ve veriler içerik analizi yöntemiyle analiz edilmiştir. Elde edilen bulgularda Sosyal Bilgiler lisans programının öğretim strateji, yöntem ve teknik, alan bilgisi, farklı bakış açıları kazanma, öğretim materyalleri ve öğretmenlik deneyimleri gibi konularda avantajlara; sınıf ve okul yönetimi, alan bilgisi, öğretmenlik deneyimi, öğretim strateji, yöntem ve teknik, öğrenci profillerini tanıma ve plan geliştirme gibi konularda ise dezavantaja neden olduğunu tespit edilmiştir. Bununla birlikte Sosyal Bilgiler öğretmenlerinin küresel gelişmeler ve yeniliklerden haberdar olma, alan bilgisi, iletişim, öğretim teknolojileri, milli ve manevi değerler gibi birtakım yeterliliklere sahip olması gerektiği sonucuna ulaşılmıştır. Ayrıca katılımcıların zorunlu, seçmeli ve programdan kaldırılacak derslere ilişkin çeşitli önerileri olduğu tespit edilmiştir. Sosyal Bilgiler lisans programına Göç ve Göçmen Eğitimi, Okul Yönetimi, Z ve Alfa Kuşağının Psikolojisi ve Eğitimi, Anayasa, Diksiyon ve Hitabet Eğitimi, İklim Değişikliği ve Çevre Sorunları gibi derslerin eklenmesine ihtiyaç duyulduğu bulunmuştur. Lisans programında öğretmenlik uygulaması, sınıf ve okul yönetimi, öğretim strateji, yöntem ve teknikleri ve uygulamalı derslerin sayılarının artırılması gibi düzenlemeler yapılması gerektiği tespit edilmiştir. Araştırma sonuçlarından yola çıkarak Sosyal Bilgiler Öğretmenliği lisans programının uygulamaya dönük ve alan konularının yoğunlukta olduğu bir yapıya kavuşturulması, teknoloji uygulamalarına ilişkin yenilikleri takip etmeye fırsat verecek niteliğe getirilmesi ve güncel olay ve sorunları içeren çağdaş konuların yer aldığı derslerin eklenmesi önerilmiştir.
Okul Öncesi Dönem Çocuklarının Duygu Düzenleme Becerileri ile Öğretmen-Çocuk İlişkisi Üzerine Bir Değerlendirme
Authors: ZEMBAT Rengin , YILMAZ Hilal
Published: June 2023

Okul öncesi dönemde çocuklar okul yaşamıyla birlikte yeni bir çevreye girerler ve bu çevre ile etkileşim sonucu duygusal olarak farklı deneyimler elde etmeye başlarlar. Bu duygular çocuğun içinde bulunduğu duruma yönelik olumlu ve olumsuz olarak değişebilmektedir. Çocuğun duygularının farkında olup, yaşadığı olaya ilişkin duygularını ifade etmesi desteklendiğinde çocuğun duygusal gelişiminde ve öğretmeni ile olan ilişkisinde etkili bir ilerleme sağlanabilecektir. Duygu düzenleme süreci çocuk ve çevresel değişkenlerin içinde yer aldığı bir süreçtir ve çocuğun yakın çevresindeki kişilerin karakterleri ve davranışlarının etkileşimi, duygu düzenlemenin gelişiminde önemlidir. Bu süreçte çocuğun öğretmeniyle kuracağı sağlıklı ve etkili iletişimin niteliğinin duygu düzenleme becerileri ile olan ilişkisinin ortaya konulması önemlidir. Bu nedenle araştırmada, okul öncesi dönem çocuklarının duygu düzenleme becerileri ile öğretmen-çocuk ilişkisi arasındaki ilişkinin incelemesi amaçlanmıştır. Araştırma nicel araştırma yöntemlerinden ilişkisel tarama modelinde tasarlanmıştır. Araştırmanın çalışma grubu İstanbul ilinde Milli Eğitim Bakanlığı’na bağlı okul öncesi eğitim kurumlarına devam eden 186 çocuktan oluşmaktadır. Araştırmanın çalışma grubu olasılığa dayalı olmayan örnekleme yöntemlerinden uygun örnekleme yöntemi ile seçilmiştir. Veri toplama aracı olarak “Duygu Düzenleme Ölçeği” ve “Öğrenci-Öğretmen İlişki Ölçeği” kullanılmıştır. Araştırmanın sonucunda okul öncesi dönem çocuklarının duygu düzenleme ve öğretmen-çocuk ilişki düzeylerinin yüksek düzeyde olduğu tespit edilmiştir. Duygu düzenleme ve öğretmen-çocuk ilişkilerinde kız çocukları lehine anlamlı bir farklılık olduğu ortaya konulmuştur. Okul öncesi dönem çocuklarının duygu düzenleme ve öğretmen-çocuk ilişkilerinin yaşlarına göre farklılık göstermediği tespit edilmiştir. Okul öncesi eğitim alma süresi 1 yıldan fazla olan çocukların duygu düzenleme ve öğretmen-çocuk ilişki düzeylerinin diğerlerinden yüksek olduğu ve çocukların duygu düzenleme becerileri ile öğretmen-çocuk ilişkisi arasında orta düzeyde, pozitif yönlü ve anlamlı bir ilişki olduğu tespit edilmiştir.
Efficiency of Bimanual Hand Coordination among Type 2 Diabetes Mellitus Adults: A Case-control Study
Authors: Jakhar Taitiksh , KShetty Ashwini , Aswathappa Jagadamba , Srinivasa SV
Published: June 2023

Introduction: Distal Peripheral Neuropathy (DPN), which first affects the lower limbs and then the upper limbs, is one of the common complications of Type 2 Diabetes Mellitus (T2DM). In addition to DPN, diabetic patients have lower muscle quality than non diabetic patients, which is exacerbated by longer duration of diabetes and poor glycaemic control. Diabetic induced peripheral neuropathy and changes in the muscle strength may interfere with bimanual coordination, which refers to a wide range of situations in which the brain must control multiple movements at the same time such as performing a task with two hands. Aim: To assess and compare Efficiency Index (EI) of bimanual coordination in T2DM and controls. Materials and Methods: This case-control study was conducted conducted in the Department of Physiology at Shri RL Jalapa Hospital, Kolar, Karnataka, India, from August 2019 to September 2019. The study included 50 participants, 25 with T2DM and 25 age matched controls. The bimanual hand coordination test apparatus was used to assess the efficiency of bimanual hand coordination. The data obtained was analysed using Statistical Package for Social Sciences (SPSS) version 20.0. Results: The mean age of the study participants was 57.16±9.54 years and controls was 54.15±5.52 years and were age matched with p-value >0.426. Mean HbA1C of the cases was 8.36±1.88 mmol/mol. There was significant decrease in efficiency of bimanual coordination among type 2 diabetics as compared to non diabetics (p-value <0.001). Conclusion: The findings of the present study showed a decrease in bimanual coordination efficiency among diabetics, indicating the importance of performing hand function tests in T2DM alongside other routine examinations.
Comparison of Dexmedetomidine and Fentanyl as an Adjuvant to Ropivacaine in Ultrasoundguided Supraclavicular Brachial Plexus Block: A Prospective Observational Study
Authors: Sanjeevan Aavani , Rajanigandha V , Harikumar A
Published: June 2023

Introduction: Upper limb surgeries are mostly performed under supraclavicular brachial plexus blocks which provide intraoperative and postoperative analgesia. Ultrasound provides clinicians with real-time images which are useful for better identification of the anatomical structures, safe needle placement, and adequate local anaesthetic spread. Adding adjuvants to local anaesthetic drugs prolong the duration of anaesthesia without concomitantly increasing the risk of complication. Aim: To compare fentanyl and dexmedetomidine when added as an adjuvant to ropivacaine for Ultrasound-guided supraclavicular brachial plexus block. Materials and Methods: A prospective observational, doubleblinded study was conducted in the Department of Anaesthesia, at Government Medical College, Kottayam, Kerala, India, on 52 patients undergoing orthopaedic upper limb surgeries over a period of one year from April 2019-March 2020. Patients were divided into two groups of 26 subjects each. Group A received ropivacaine 0.5% (20 mL)+dexmedetomidine 1 mcg/kg and group B received ropivacaine 0.5% (20 mL)+Fentanyl 1 mcg/kg. Onset, time to complete sensory and motor block, duration of sensory and motor block, duration of analgesia, adverse effects and haemodynamic status were monitored. Statistical analysis was done using t-test and Chi-square test. Results: The demographic variables, onset of sensory and motor block were comparable in both the groups. Mean duration of sensory block in group A and B were 638.08±52.001 minutes and 568.85±36.478 minutes respectively. The mean duration of motor block in group A was 605.77±58.8 minutes and group B was 513.46±14.982 minutes. The mean duration of analgesia in group A and B were 722.3±58.13 and 615.00±48.19 minutes, respectively. Mean duration of sensory block, motor block and analgesia were found more in group A which was statistically significant with p-value=<0.05. There was no significant difference in haemodynamic parameters. Conclusion: Dexmedetomidine was a better adjuvant to 0.5% ropivacaine as compared to fentanyl in Ultrasound-guided supraclavicular brachial plexus block in terms of duration of sensory block, motor block and analgesia.
Effect of Intravenous Etomidate versus Propofol on Seizure duration and Haemodynamic Response during Modified Electroconvulsive Therapy: A Randomised Clinical Trial
Authors: Vishwas GK , Ashwini GS , Deepak RS , Sanikop CS , Shivavanand LK , Edwin Suzanne Sonali
Published: June 2023

Introduction: Seizure duration in Electro convulsive Therapy (ECT) is a clinically important factor in managing psychiatric patients subjected to the procedure. Various induction agents are being used with varying efficacy on seizure duration and haemodynamic response like thiopentone, propofol, ketamine and etomidate. As repeated ECT sessions pose significant risk of general anaesthesia and its complications, in this study the efficacy of etomidate and propofol was compared. Aim: To assess the seizure duration and compare haemodynamic variables using etomidate and propofol. Materials and Methods: A randomised clinical trial was done in the Department of Anaesthesiology, at tertiary care hospital between July 2021 to June 2022 on 40 patients of age group 18 to 60 years of either sex, belonging to American Society of Anaesthesiologists (ASA) Grade-I and II scheduled for ECT. Patients were allocated into two groups. Preinduction baseline values of Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP) and Mean Arterial Pressure (MAP) were recorded using pulse oximeter and Non Invasive Blood Pressure (NIBP). Patients were induced with either, inj. etomidate 0.2 mg/ kg (Group E) or inj. propofol 1 mg/kg (Group P). HR, SBP, DBP and MAP were recorded soon after induction, after application of stimulus and at one minute interval after electric 156 shock for five minutes and then at five minutes interval. Statistical analysis was done by using the unpaired Student’s t-test for quantitative data. The p-value <0.05 was considered significant. Results: Demographic data were similar in both the groups. The mean seizure duration in Group E (51.25±9.01 seconds) was greater than in Group P (38.30±9.92 seconds) and was statistically significant. There was significant increase in the HR in both groups and the HR did not reach the baseline even after 10 minutes. There was a rise in the mean SBP by approximately 7 mm Hg in the Group P compared to 4 mm Hg in the Group E. The mean DBP rise in the propofol group was 6 mm Hg as compared to 5 mm Hg in the Group E. The MAP in both the groups increased by 7 mm Hg. The parameters reached the baseline earlier with Group P compared to Group E. Conclusion: The study concludes etomidate has a distinct advantage over propofol in producing seizures of adequate duration during ECT whereas propofol blunts the sympathetic response to ECT more effectively than etomidate.
Marketing Cost, Producer's Share, and Marketing Efficiency in Different Marketing Channels of Persimmon Crop in Kullu District of Himachal Pradesh
Authors: Thakur Devashish , Maurya Mukesh Kumar , Tiwari Madhusudan
Published: June 2023

This study examines the marketing channels and associated costs in the persimmon industry, focusing on the producer's share in consumer rupees and marketing efficiency. The research analyzes different marketing channels involving wholesalers, retailers, and pre-harvest contractors. The findings reveal the marketing costs incurred by various stakeholders, with variations observed across channels. The producer's marketing cost ranged from ₹187.40 to ₹245.86 per quintal, while wholesalers, pre-harvest contractors, and retailers incurred significant costs in terms of commissions, transportation, taxes, and other expenses. The analysis of price spread among channels highlights the net price received by the producer, consumer's price, and marketing margins. Moreover, the study evaluates the marketing efficiency of each channel, indicating their effectiveness in terms of cost management and value delivery. The marketing efficiency values obtained for Channel-1, Channel-2, and Channel-3 are 5.48, 3.10, and 2.44, respectively. These results provide insights into the distribution of profits and costs among different stakeholders in the persimmon industry, aiding in understanding the overall performance of marketing channels.
Characteristics (Yield, Moisture Content, Water Absorption, Ph, and Organoleptic) of Catfishflour (Pangasius hypophthalmus)
Authors: Junianto  , Rakan Ditidewa Aristia , Zaenal Ajid , Imani Ratu Farra Haifa , Alphareza Ijlal Akmal , Pratama Lucky Mahesa Anugrah , Khansa Deswita
Published: June 2023

Fish meal is a dry solid product, produced by removing most of the liquid and some or all of the fat contained in the body of the fish. This research aims to analyze the characteristics of catfish flour that is given preliminary treatment, namely steamed and boiled and control (without heating) before the drying process. This research is divided into 2 stages, namely phase I research on making fish meal from Patin Fish (Pangasius hypopthalmus) with 3 treatments, namely control, boiling, and steaming and phase II research, namely the test characteristics on catfish meal such as yield tests, organoleptic tests, absorption, water content, and pH.Based on the results of research on the characteristics of catfish flour obtained from the first treatment, control on fish meat before drying is as follows: flour yield 21.7 ± 0.54%; moisture content 5.9 %; absorbency 1.28 %; pH 5.93; and very pungent aromatic organoleptic character, coarse powder and brownish color. Thecharacteristics of catfish flour obtained from the second treatment, namely boiling on fish meat before drying, are as follows: flour yield 12.33%; moisture content 1.8%;absorbency 1.6%; pH5.8; and fish-scented organoleptic character in general, semi-fine, yellowish in color. Thecharacteristic of catfish flour obtained from the third treatment, namely steaming on fish meat before drying, is as follows: flour yield 13.37%; moisture content 2.2%; absorbency 1.8%; pH 5.5; and organoleptic character of non-pungent aroma, fine powder, and yellowish-whitecolor.
Spatial Characteristics of Public Active Recreational Facilities in Uyo Urban, Akwa Ibom State, Nigeria
Authors: Ofem B. I. , Ufot-Akpabio A. M.
Published: June 2023

In recent times there has been increasing use of active recreational facilities in urban centers the world over. However, in Nigeria, patronage is hindered by their location and distribution. The study aimed to assess the spatial characteristics of active recreational facilities in Uyo urban, Akwa Ibom State. Empirical and exploratory methods were employed. Questionnaire was administered and field observations were conducted to gather data for analysis. A random sampling technique was used to determine a total sample size of 400 for questionnaire distribution. There were nine (9) active recreational facilities within the study area whose locations and pattern were determined using the Nearest Neighbourhood Analysis technique. The study revealed that characteristically, the active recreational facilities were located dispersed, which was a pointer to a lack of order and planning in their location. Based on the findings, it is recommended that; more active recreational facilities should be provided, optimally and equidistantly located to enhance usage.