bluuebunny/crossref_metadata_2025 huggingface dataset:
Extended composite index of anthropometric failure in Argentinean preschool and school children
Authors: Bejarano IF , Oyhenart EE , Torres MF , Cesani MF , Garraza M , Navazo B , Zonta ML , Luis MA , Quintero FA , Dipierri JE , Alfaro E , Román EM , Carrillo R , Dahinten S , Lomaglio DB , Menecier N , Marrodán MD
Published: October 2019

Objective:

The Composite Index of Anthropometric Failure (CIAF) can only be applied to children under 5 years of age and does not contemplate obesity. The aim of this study was to propose an Extended CIAF (ECIAF) that combines the characterization of malnutrition due to undernutrition and excess weight, and apply it in six Argentine provinces.

Design:

ECIAF excludes children not in anthropometric failure (group A) and was calculated from a percentage of children included in malnutrition categories B: wasting only; C: wasting and underweight; D: wasting, stunting and underweight; E: stunting and underweight; F: stunting only; Y: underweight only; G: only weight excess; and H: stunting and weight excess.

Setting:

Cross-sectional study conducted in Buenos Aires, Catamarca, Chubut, Jujuy, Mendoza and Misiones (Argentina).

Participants:

10 879 children of both sexes aged between 3 and 13·99.

Results:

ECIAF in preschool children (3 to 4·99 years) was 15·1 %. The highest prevalence was registered in Mendoza (16·7 %) and the lowest in Misiones (12·0 %). In school children (5 to 13·99 years) ECIAF was 28·6 %. Mendoza also recorded the highest rate (30·7 %), while Catamarca and Chubut had the lowest values (27·0 %). In the whole sample, about 25 % of the malnutrition was caused by undernutrition and 75 % by excess weight.

Conclusions:

The ECIAF summarizes anthropometric failure by both deficiency and excess weight and it highlights that a quarter of the malnutrition in the Argentine population was caused by undernutrition, although there are differences between Provinces (P < 0·05). ECIAF estimates are higher than those of CIAF or under-nutrition.
Implementing dementia risk reduction in primary care: a preliminary conceptual model based on a scoping review of practitioners’ views
Authors: Godbee Kali , Gunn Jane , Lautenschlager Nicola T , Curran Eleanor , Palmer Victoria J
Published: October 2019

Primary care practitioners (PCPs) do not routinely promote dementia risk reduction. The purpose of this study was to map the published literature on the views of PCPs about dementia risk reduction, in order to identify implementation constructs and strategies crucial to the development of an implementation intervention to support dementia risk reduction in primary care. We undertook a scoping review of the PCPs’ views about promoting brain health for reducing dementia risk. We searched MEDLINE, PsycINFO, CINAHL, and Embase for English-language articles published between 1995 and December 2017. We then applied the Consolidated Framework for Implementation Research (CFIR) and matched Expert Recommendations for Implementing Change to the scoping review findings in order to develop a preliminary implementation model. Eight articles reported views of PCPs about dementia prevention. Study findings were mapped to 5 of the 39 CFIR constructs: (i) knowledge and beliefs about dementia risk reduction, (ii) evidence strength and quality, (iii) relative priority, (iv) available resources, and (v) external policy and incentives. The findings suggest implementation strategies to consider in our preliminary model include (i) educational meetings, (ii) identifying and preparing champions, (iii) conducting local consensus discussions, (iv) altering incentive structures, and (v) capturing and sharing local knowledge. There have been few studies about the views of PCPs about dementia risk reduction. Implementation in the primary care setting is fundamental to early identification of risk and supporting preventive practices, but it needs to focus on more than just education for PCPs. We need more up-to-date and in-depth data on the views of PCPs about dementia risk reduction and context-specific analyses of implementation needs. Further research into effective primary care interventions to reduce dementia risk is expected to support implementation efforts.
FinnTwin12 Cohort: An Updated Review
Authors: Rose Richard J. , Salvatore Jessica E. , Aaltonen Sari , Barr Peter B. , Bogl Leonie H. , Byers Holly A. , Heikkilä Kauko , Korhonen Tellervo , Latvala Antti , Palviainen Teemu , Ranjit Anu , Whipp Alyce M. , Pulkkinen Lea , Dick Danielle M. , Kaprio Jaakko
Published: October 2019

This review offers an update on research conducted with FinnTwin12 (FT12), the youngest of the three Finnish Twin Cohorts. FT12 was designed as a two-stage study. In the first stage, we conducted multiwave questionnaire research enrolling all eligible twins born in Finland during 1983–1987 along with their biological parents. In stage 2, we intensively studied a subset of these twins with in-school assessments at age 12 and semistructured poly-diagnostic interviews at age 14. At baseline, parents of intensively studied twins were administered the adult version of the interview. Laboratory studies with repeat interviews, neuropsychological tests, and collection of DNA were made of intensively studied twins during follow-up in early adulthood. The basic aim of the FT12 study design was to obtain information on individual, familial and school/neighborhood risks for substance use/abuse prior to the onset of regular tobacco and alcohol use and then track trajectories of use and abuse and their consequences into adulthood. But the longitudinal assessments were not narrowly limited to this basic aim, and with multiwave, multirater assessments from ages 11 to 12, the study has created a richly informative data set for analyses of gene–environment interactions of both candidate genes and genomewide measures with measured risk-relevant environments. Because 25 years have elapsed since the start of the study, we are planning a fifth-wave follow-up assessment.
Tracking-Systeme bei Menschen mit Demenz in der stationären Langzeitpflege
Authors: Hülsken-Giesler Manfred , Peters Miriam , Müller Kathrin
Published: October 2019

Zusammenfassung. Hintergrund: Tracking-Systeme werden in der stationären Langzeitpflege zunehmend eingesetzt. Ihr Einsatz ist jedoch fachlich umstritten. Fragestellung: Der Beitrag geht der Frage nach, wie Tracking-Systeme für das Monitoring von Menschen mit Demenz in Einrichtungen der stationären Langzeitpflege angewendet werden und welche Konsequenzen sich daraus für Bewohnerinnen und Bewohner sowie für das Personal ergeben. Methode: Es wurde eine systematische Literaturrecherche in den Datenbanken PubMed, CINAHL, Livivo und ScienceDirect und eine Handsuche durchgeführt. Eingeschlossen wurden Studien, Reviews und Forschungsberichte in deutscher und englischer Sprache ab 2013. Ergebnisse: Insgesamt wurden acht Referenzen in die Analyse einbezogen. Die Ergebnisse verweisen auf einen ambivalenten Umgang mit Tracking-Systemen in der Pflege. Für Pflegefachpersonen zeigen sich Herausforderungen im Spannungsfeld von Vertrauen und Misstrauen sowie Autonomie und Sicherheit. Für Bewohnerinnen und Bewohner ergeben sich neue Freiräume für Mobilität und Selbstbestimmung, andererseits aber neue Belastungen durch kontinuierliche Kontrolle. Schlussfolgerungen: Die Ergebnisse zeigen, dass sich die Debatte um den Einsatz von Tracking-Systemen bei Menschen mit Demenz in der stationären Langzeitpflege derzeit stark auf ökonomische Aspekte konzentriert, Aspekte der personenzentrierten Pflege, ethische Konflikte oder das Erleben der Betroffenen dagegen weniger thematisiert werden. Eine zentrale Erkenntnis besteht darin, dass sich über den Technologieeinsatz die Arbeitsprozesse und Rollen von professionell Pflegenden verändern.
Mantle Melting and Intraplate Volcanism Due to Self‐Buoyant Hydrous Upwellings From the Stagnant Slab That Are Conveyed by Small‐Scale Convection
Authors: Long Xiaogang , Ballmer Maxim D. , Córdoba Antonio M.‐C. , Li Chun‐Feng
Published: October 2019

The mechanisms sustaining basaltic continental intraplate volcanism remain controversial. Continental intraplate volcanism is often geographically associated with slab stagnation in the mantle transition zone (MTZ), for example, in eastern Asia, central Europe, and western North America. Using 2‐D geodynamic models, we here explore the role of the stagnation of a slab and an associated hydrous layer in the MTZ on the formation and evolution of intraplate volcanism. Due to the intrinsic buoyancy of the hydrous layer atop the stagnant slab, upwellings develop within a few million years and rise to ~410‐km depth. At these depths, they partly lose their intrinsic buoyancy due to dehydration and stall intermittently. However, they are readily entrained by sublithospheric small‐scale convection to reach the base of lithosphere, sustaining mantle melting and intraplate volcanism. Water contents of >0.3 wt.‐% in a ≥ 60‐km‐thick layer atop the slab are sufficient for an early (<~20 Myr) onset of melting to account for volcanism, for example, in NE China. Thus, significant amounts of hydrous materials are not expected to remain stable in the MTZ for geological timescales, consistent with geophysical estimates. To explain the geochemical signatures of the Cenozoic basaltic volcanism in northern China, a mixed composition of the hydrous layer, including an enriched mantle‐type and a hybrid depleted mid‐ocean ridge basalts mantle/high μ‐type component, is required.
Added Value of a Dynamical Downscaling Approach for Simulating Precipitation and Temperature Over Tianshan Mountains Area, Central Asia
Authors: Chen Shuying , Hamdi Rafiq , Ochege Friday Uchenna , Du Haoyang , Chen Xi , Yang Weikang , Zhang Chi
Published: October 2019

Progresses in climatological, ecological, and hydrological studies that focused on the Tianshan mountains area (known as “the water tower of central Asia”) have been restricted by the availability of station observations as well as high resolution and quality data set. With the aim to overcome some of these difficulties, the high‐resolution Weather Research and Forecasting (WRF) regional climate model is run over the Tianshan mountains area driven by the ERA‐Interim reanalysis. Double nesting method was used with a horizontal resolution of 40 and 8 km covering the period 1980–2018. A decade of simulation from 1980 to 1989, a period when most abundant station observations are available, is considered for validation. These downscaled results are compared against station observations, ERA‐Interim reanalysis, and three widely used spatially interpolated products in order to investigate the added value of the dynamical downscaling approach. Results of these comparisons show that the WRF‐downscaled data outperform and add significant details to ERA‐Interim reanalysis. A remarkable improvement of the WRF simulation is found at reproducing the observed seasonal cycle of daily extreme temperatures and precipitation. Due to better representation of orography, WRF simulations are able to capture extreme precipitation events that are missing in the high‐quality interpolated products. Refining the resolution from 40 to 8 km further improves the model performance, particularly at depicting orographic enhancement of precipitation. The validated WRF model can be used in future climate projections studies, and this high‐resolution as well as high‐quality climatological data set we present here is useful for impact and further downstream studies.
Correction to: Myocardin regulates mitochondrial calcium homeostasis and prevents permeability transition
Authors: Mughal Wajihah , Martens Matthew , Field Jared , Chapman Donald , Huang Jianhe , Rattan Sunil , Hai Yan , Cheung Kyle G. , Kereliuk Stephanie , West Adrian R. , Cole Laura K. , Hatch Grant M. , Diehl-Jones William , Keijzer Richard , Dolinsky Vernon W. , Dixon Ian M. , Parmacek Michael S. , Gordon Joseph W.
Published: October 2019

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Correction to: Nrf3 promotes UV-induced keratinocyte apoptosis through suppression of cell adhesion
Authors: Siegenthaler Beat , Defila Claudia , Muzumdar Sukalp , Beer Hans-Dietmar , Meyer Michael , Tanner Sandra , Bloch Wilhelm , Blank Volker , Schäfer Matthias , Werner Sabine
Published: October 2019

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Correction: Salvador–Warts–Hippo pathway regulates sensory organ development via caspase-dependent nonapoptotic signaling
Authors: Wang Lan-Hsin , Baker Nicholas E.
Published: October 2019

Following publication of this article, it was brought to our attention that there was a typo in the References (reference number 43) whereby the first author’s name was misspelled. The correct citation is provided below. We apologize for the inconvenience.
Knickpoints in Martian channels indicate past ocean levels
Authors: Duran Sergio , Coulthard Tom J. , Baynes Edwin R. C.
Published: October 2019

On Mars, the presence of extensive networks of sinuous valleys and large channels provides evidence for a wetter and warmer environment where liquid water was more abundant than it is at present. We undertook an analysis of all major channel systems on Mars and detected sharp changes in elevation along the river long profiles associated with steep headwall theatre-like valleys and terraces left downstream by channel incision. These breaks in channel longitudinal slope, headwalls and terraces exhibit a striking resemblance with terrestrial fluvial features, commonly termed ‘knickpoints’. On Earth, such knickpoints can be formed by more resistant bedrock or where changes in channel base-level have initiated erosion that migrates upstream (such as tectonic uplift or sea level change). We observed common elevations of Martian knickpoints in eleven separate channel systems draining into the Martian Northern lowlands. Numerical modeling showed that the common elevations of some of these knickpoints were not random. As the knickpoints are spread across the planet, we suggest that these Martian knickpoints were formed in response to a common base level or ocean level rather than local lithology. Thus, they potentially represent a record of past ocean levels and channel activity on Mars.
A nanofluidic memristor based on ion concentration polarization
Authors: Bu Yang , Ahmed Zisun , Yobas Levent
Published: October 2019

The very first nanofluidic memristor based on the principle of ion concentration polarization (ICP).
Inhibiting guanine oxidation and enhancing the excess-electron-transfer efficiency of a pyrene-modified oligonucleotide by introducing an electron-donating group on pyrene
Authors: Okuda Takumi , Kawashima Yusuke , Kasahara Yuuya , Takagi Tatsuya , Yamamoto Junpei , Iwai Shigenori , Obika Satoshi
Published: October 2019

PipPyU and OMePyU enhance the reduction efficiency without oxidizing guanine in DNA-mediated electron transfer.
Uricase-containing coacervate microdroplets as enzyme active membrane-free protocells for detoxification of uric acid in serum
Authors: Zhuang Miaomiao , Zhang Yanwen , Zhou Shaohong , Zhang Yun , Wang Kemin , Nie Jinfang , Liu Jianbo
Published: October 2019

Based on the unique property of preferential sequestration of guest molecules, coacervate microdroplets are proposed as enzyme active membrane-free protocells, in which uricase is loaded for efficient detoxification of uric acid in serum.
A novel Mn/Co dual nanoparticle decorated hierarchical carbon structure derived from a biopolymer hydrogel as a highly efficient electro-catalyst for the oxygen reduction reaction
Authors: Cao Lujie , Wang Zhenyu , Liu Jinlong , Wang Bingxue , Wang Zhiqiang , Yang Mingyang , Pan Hui , Lu Zhouguang
Published: October 2019

A Mn/Co dual nanoparticle-decorated hierarchical carbon structure was derived from a Zn/Mn/Co/chitosan composite hydrogel as a highly efficient electro-catalyst for the oxygen reduction reaction.
Insights into the electrochemical capacitor performance of transition metal–vertical graphene nanosheet hybrid electrodes
Authors: Sahoo Gopinath , Polaki S. R. , Anees P. , Ghosh Subrata , Dhara Sandip , Kamruddin M.
Published: October 2019

The enhanced electrochemical capacitance of the transition metal-vertical graphene nanosheet hybrid electrodes are correlated with the increase in charge transfer supported ab initio DFT calculations and increase in electrical conductivity.
Correction: Epoxide ring-opening reaction promoted by ionic liquid reactivity: interplay of experimental and theoretical studies
Authors: Chen Shengxin , Zeng Guixiang , Li Yingwei , He Bin , Liu Ruixia , Zhang Suojiang
Published: October 2019

Correction for ‘Epoxide ring-opening reaction promoted by ionic liquid reactivity: interplay of experimental and theoretical studies’ by Shengxin Chen et al., Catal. Sci. Technol., 2019, DOI: 10.1039/c9cy00953a.
The red and blue luminescence in silicon nanocrystals with an oxidized, nitrogen-containing shell
Authors: Galář Pavel , Popelář Tomáš , Khun Josef , Matulková Irena , Němec Ivan , Newell Kateřina Dohnalova , Michalcová Alena , Scholtz Vladimír , Kůsová Kateřina
Published: October 2019

Upon exposure to nitrogen, blue photoluminescence of silicon nanocrystals is observed to diminish, while red photoluminescence is preserved.
Irreversibility of arsenic trioxide induced PML/RARα fusion protein solubility changes
Authors: Maimaitiyiming Yasen , Shao Yi Ming , Chen Wei Zhong , Jiang Yu , Bu Na , Ma Li Ya , Wang Qian Qian , Lu Xiao Yang , Naranmandura Hua
Published: October 2019

Arsenic trioxide induced PML/RARα fusion protein solubility change is an irreversible process, and the insoluble protein can be further degraded by the proteasomal pathway even without continuous exposure to arsenic.
HClO4 catalysed aldol-type reaction of fluorinated silyl enol ethers with acetals or ketals toward fluoroalkyl ethers
Authors: Tian You-Ping , Gong Yi , Hu Xiao-Si , Yu Jin-Sheng , Zhou Ying , Zhou Jian
Published: October 2019

A highly efficient metal-free catalytic aldol-type reaction of fluorinated enol silyl ethers and acetals/ketals toward functionalized fluoroalkyl ethers is developed by using less than 1.0 mol% HClO4 (70 wt%, aq.).
A Sc(OTf)3 catalyzed dehydrogenative reaction of electron-rich (hetero)aryl nucleophiles with 9-aryl-fluoren-9-ols
Authors: Zhou Chen , Hu Chen , Hong Gang , He Yuchen , Tang Zhicong , Wang Limin
Published: October 2019

New pyrenyl substituted 9,9-diarylfluorene with nonplanar conformations, high fluorescence quantum yield and excellent thermal and morphological stability was synthesized by our current protocol.
Autonomic Nervous System Response to Speech Production in Stuttering and Normally Fluent Preschool-Age Children
Authors: Tumanova Victoria , Backes Nicole
Published: October 2019

Purpose

We studied speech-related sympathetic nervous system arousal of preschool-age children who do (CWS) and do not stutter (CWNS) and its association with children's proclivity to experience negative emotions and children's self-reported attitudes toward speaking.

Method

Electrodermal activity measures were collected from 32 preschool-age children while they engaged in a picture description and a nonword repetition task. Children's proclivity to experience negative emotions was assessed with a parent report questionnaire. Children's communication attitude was assessed with a self-report questionnaire.

Results

CWS did not differ from CWNS in their sympathetic arousal during a picture description task. However, during a more challenging nonword repetition task, preschool-age CWS had a higher sympathetic arousal level than CWNS. Although CWS were rated by their caregivers as more fearful and prone to sadness, children's tendency to experience stronger and more frequent negative emotions was not associated with their sympathetic arousal during speaking. Lastly, although CWS had a more negative communication attitude than CWNS, it was not associated with their level of sympathetic arousal during speaking.

Conclusions

Our findings suggest that age-appropriate social communication tasks are not inherently more stressful for preschool-age CWS and are not associated with state-related stress or anxiety that is often reported for adults who stutter. However, speaking tasks that place a higher demand on children's cognitive–linguistic system may be more taxing and challenging to preschool CWS than CWNS, leading to a higher level of arousal.
Observational constraints on the origin of the elements
Authors: Gallagher A. J. , Bergemann M. , Collet R. , Plez B. , Leenaarts J. , Carlsson M. , Yakovleva S. A. , Belyaev A. K.
Published: October 2019

Context. The pursuit of more realistic spectroscopic modelling and consistent abundances has led us to begin a new series of papers designed to improve current solar and stellar abundances of various atomic species. To achieve this, we have begun updating the three-dimensional (3D) non-local thermodynamic equilibrium (non-LTE) radiative transfer code, MULTI3D, and the equivalent one-dimensional (1D) non-LTE radiative transfer code, MULTI 2.3.

Aims. We examine our improvements to these codes by redetermining the solar barium abundance. Barium was chosen for this test as it is an important diagnostic element of the s-process in the context of galactic chemical evolution. New Ba II + H collisional data for excitation and charge exchange reactions computed from first principles had recently become available and were included in the model atom. The atom also includes the effects of isotopic line shifts and hyperfine splitting.

Methods. A grid of 1D LTE barium lines were constructed with MULTI 2.3 and fit to the four Ba II lines available to us in the optical region of the solar spectrum. Abundance corrections were then determined in 1D non-LTE, 3D LTE, and 3D non-LTE. A new 3D non-LTE solar barium abundance was computed from these corrections.

Results. We present for the first time the full 3D non-LTE barium abundance of A(Ba) = 2.27 ± 0.02 ± 0.01, which was derived from four individual fully consistent barium lines. Errors here represent the systematic and random errors, respectively.
The climate change influences and trends on the grapevine growing in Southern Romania: A long-term study
Authors: Bucur G.M. , Cojocaru G.A. , Antoce A.O.
Published: October 2019

The topography and pedoclimatic conditions in Romania are diverse and in many places highly favourable for viticulture. In the past 21 years it was observed that the climate slowly changed, with a visible impact on grape quality. The influence of climate change on grape growing depends however on the vineyard location, relief and soil, multiple combination of varieties and rootstocks, water supply, as well as viticultural practices. The influence of the climate change was studied during a long period of time, between 1998 and 2018, in our experimental vineyard at UASVM Bucharest (N Lat.: 44∘47′07′′; E Long.: 26∘076′28′′; elevation 87 m), located in the Southern part of Romania. The observations made during last twenty one years on qualitative and quantitative parameters of the most widespread Romanian grape variety, Fetească regală grafted on the Kober 5 BB rootstock, along with the calculated values for the usual climatic indices describing viticultural climate, showed some significant climate changes in comparison with a reference period between 1961 and 1997 taken from the existent scientific literature. Our observations during past twenty years reveal a trend of increase in all studied temperature-dependent climatic indices during the grape growing season, with a large variation in the absolute minimum temperatures during winter, which suggests a shift towards an increased thermal amplitude between summer and winter temperatures in certain years. Compared with the reference period (1961–1997), an increase in the following temperature-dependent indices was observed: +0.75 ∘C for the average annual temperature; +0.78 ∘C for average temperature in the growing season; +2.37 ∘C for average maximum temperature in the warmest month; +2.11 ∘C for average maximum temperature in the summer; +234 units in Huglin index; + 173 units in Winkler index and +0.35 ∘C in Cool night index. These climate changes bring important variations of grape yield due to the minimum temperatures during winter and significant reduction of total acidity, along with a significant increase of sugar concentration. This study aids to understand and anticipate the rate of climate change in Southern Romania, the extent of the changes in grape quality and the interventions required to maintain constant grape and wine quality.
Evoluzione della tecnica d'innesto su barbatella radicata
Authors: Perniola R. , Forleo L.R. , Marsico A.D.
Published: October 2019

In viticoltura, per la realizzazione di nuovi impianti sono utilizzate piante bimembri ottenute in vivaio o direttamente in campo. Negli ultimi anni, allo scopo di ottenere rapidamente nuovi impianti, si sta diffondendo la tecnica dell'innesto su barbatella radicata. Tale tecnica, realizzata in vivaio, prevede l'innesto a tavolino delle marze della varietà scelta su barbatelle radicate di portainnesto di specie diVitisamericane. Dopo un periodo di forzatura e ambientamento in vivaio, le piantine vengono messe a dimora in campo, nello stesso anno di realizzazione dell'innesto. Al fine di valutare tale tecnica, presso il CREA – Viticoltura ed enologia sede di Turi, è stata sperimentata la possibilità di utilizzare due differenti tipologie d'innesto su diversi portinnesti. Per assicurare una buona resistenza del punto d'innesto ed una buona protezione dalla contaminazione e dalla disidratazione è stato utilizzato un materiale di saldatura costituito da una pellicola elastica e semitrasparente. La sperimentazione è stata condotta per due anni, su 12 varietà di uve da tavola di recente costituzione. I risultati hanno mostrato buoni attecchimenti e saldatura dei bionti. Alcune differenze sono state riscontrate sui portinnesti utilizzati e sui tempi di germogliamento dopo l'innesto.
The emergent diseases in grapevine nursery: Critical point analysis for developing a protected and sustainable propagation process
Authors: Battiston E. , Di Marco S. , Angelini E. , Mugnai L.
Published: October 2019

The diffusion of emergent pathogens in grapevine nursery is increasingly compromising the sanitary quality of the propagation material. The complexity of the problem lies on the plurality of plant diseases involved and on the high environmental and economic impact of the conventional methods applied to comply the phytosanitary standards. By a critical point analysis, the study suggests the development of nursery strategies focused on the sanitary quality of the production and on its long-term environmental sustainability.
A tool for technical and economic evaluation of dieback in wine-growing holdings
Authors: Mahé H. , Riou C. , Longepierre P. , Imberti M.-H. , Mahé L. , Prêtet-Lataste C.
Published: October 2019

Dieback in the vineyards is causing a long-term decline in the productivity of the vine stock and/or its sudden or gradual premature death, related to a number of different factors. It is a problem in all wine regions around the world. Its economic importance was estimated to represent €2 billion turnover in 2020 if the trend in yield loss continues at the same pace. How do we diagnose dieback in the wine-growing holdings to provide a better understanding of the risks and to respond? The aim of the work is to identify the factors to be taken into consideration in the development of a dieback self-diagnosis tool for wine growers. The first study takes into account all aspects of the wine-growing system in very mixed French conditions of production. The survey was fielded in 124 wine-growing and contains over a hundred questions. The analysis and classification of the holdings are based on yield and longevity which are constructed from socio-technical and economic data, complementing the agronomic aspects. These parameters have been combined to create a classification of wine-growing holdings affected by dieback. The finished tool is based on the answers to 30 questions identified by the survey. We can calculate a score that places the winery in relation to other wineries in the same situation.
Preservation, innovation and governance: Geographical indication of grapes in Jundiaí (Brazil)
Authors: Verdi A.R.
Published: October 2019

The formation of the grape growing area of Jundiaí was influenced by Italian immigration and the diffusion of cultivar Isabella. After 1930, the coffee economy crisis, the destructuring of the large monoculture property and the emergence of the Niagara Rosada cultivar allowed for the specialization of the Jundiaí grape growing agglomeration. The diffusion of this cultivar characterized the physiognomy of the regional vineyard with the practice of the “espalier” conduction system, and developed the intangible heritage based on the religious character of the cultural manifestations and harvest celebrations. Currently, urban and industrial expansion provides negative externalities of the geographic proximity between the diverse uses of the agricultural space, a fact that imposes threats to the sustainability of the traditional grape growing activities. This work is based on the hypothesis that the Geographical Indication of the Niagara Rosada grape presupposes governance among the agents and constitutes a project of valuation of the traditional landscape and the cultural heritage, in order to contribute to adding value to the grape and to territorial development. The specific resources, even outside the market sphere, can contribute to the commercial valuation of the Niagara Rosada grape and wealth generation beyond the classic notion of “productivity”.
“EnoAventura na Serra Catarinense” – the game: Rural tourism as a fortress to leverage enotourism and winemaking education in the region with the lowest human development index in the state of Santa Catarina, Brazil
Authors: de Vasconcellos Dullius M. , da Silva I.R. , Santa Rosa B.R.
Published: October 2019

In the state of Santa Catarina (SC), south of Brazil, extends the region of “Planalto Catarinense”, which is divided into 18 municipalities comprised within the geographic limits of the “Serra Catarinense”. The vine, in the “Planalto Catarinense” is the second fruit cultivation of commercial relevance, and it is boosting the tourism in the region. Exploring the enotourism is perhaps one of the most promising attractions connecting the incipient wine region with the unique landscape. With the purpose of contributing to the enotouristic complex cluster, this work aimed at creating a board game highlighting featured tourist points of each of the 18 municipalities of “Serra Catarinense”. The game presents itself as a playful tool that brings concepts of viticulture and oenology and incorporates the tourist and gastronomic attributes of mountainous region, notoriously lacking in economic development strategies that generate employment, income and life improvement. The game is a bet and it seeks to offer new insights into the classic themes surrounding grape and wine production, professional education and promising economic development for the “Serra Catarinense”.
Physicien célèbre : Max von Laue
Authors: Bonod Nicolas
Published: October 2019

Max von Laue est un physicien théoricien allemand spécialiste de la diffraction des ondes, de la relativité et de la superconductivité. Il propose en 1912 de sonder l’arrangement périodique de la matière avec des faisceaux de courtes longueurs d’onde, les rayons X ; et sera récompensé par le prix Nobel de Physique en 1914. La découverte de la diffraction des rayons X par des cristaux sera à l’origine d’avancées majeures dans les 100 ans qui suivirent, de la découverte de la structure de l’ADN à celle des quasi-cristaux.
Le Lignon retrouve son cours naturel (Haute-Loire)
Authors: Darne E. , Louche K.
Published: October 2019

L’action, conduite à Fay-sur-Lignon en Haute-Loire, a permis au Lignon de retrouver son lit d’origine et de nouvelles fonctionnalités. Situé en tête du bassin versant du Lignon du Velay, un plan d’eau avait été créé sur une ancienne zone humide en barrant la rivière. À la suite d’une destruction par une crue centennale, il a été reconstruit à la même place, mais le Lignon a été détourné de son tracé naturel. Cette mise en dérivation du Lignon a entraîné un déséquilibre morphodynamique tandis que la présence du plan d’eau générait plusieurs perturbations sur les milieux : perte d’habitats naturels, impact sur la qualité et le réchauffement de l’eau, limitation du rôle de soutien d’étiage et d’expansion de crue, perturbation de la continuité écologique. Le plan d’eau avait, par ailleurs, un attrait et un usage limité, bien que ce soit le développement touristique local qui ait motivé initialement sa création. Pour réduire ces perturbations ainsi qu’un risque de rupture d’une digue, un projet de réhabilitation du Lignon dans son lit historique a été étudié puis mis en œuvre par le Sicala de Haute-Loire (Syndicat d’aménagement de la Loire et ses affluents). Grâce à l’engagement des acteurs locaux, ce plan d’eau a pu être effacé et le Lignon a pu retrouver le cours qu’il empruntait 45 ans plus tôt à quelques ajustements près. Le projet a ainsi permis d’ouvrir un nouvel espace de liberté pour la rivière, favorable à la restauration d’une zone alluviale et de milieux associés, et à la recolonisation par les espèces emblématiques de cette tête de bassin (Salmo trutta Linneaus, 1758, Castor fiber Linnaeus, 1758). Dans un esprit de développement durable, le site réhabilité servira aussi d’espace récréatif pour l’accueil du public tout en préservant les écosystèmes et les zones refuges pour la biodiversité.
Opération de restauration d’une roselière dans le marais noir de Saint-Coulban (35)
Authors: Hemon A. , Drouyer F.
Published: October 2019

En périphérie de la baie du Mont-Saint-Michel, le site du « Bois de la mare » dans le marais noir de Saint-Coulban est un ensemble de 16 hectares de terrains boisés dans les années 1960 en peupliers et épicéas, jamais exploités et présentant peu d’intérêt patrimonial, sylvicole ou paysager. Une opération de restauration de roselière en faveur de l’avifaune paludicole a été réalisée sur ce site. Ce projet est porté par la Fédération des chasseurs d’Ille-et-Vilaine, gestionnaire des terrains, et le Syndicat mixte Baie du Mont-Saint-Michel, maître d’ouvrage de l’opération de rétablissement du caractère maritime du Mont-Saint-Michel. La collaboration entre ces deux organismes repose sur des objectifs convergents. Dans le marais, la fédération procède depuis 1983 à des opérations d’acquisition et de restauration de milieux humides, à des fins d’accueil de l’avifaune. De son côté, le syndicat mixte est chargé de la mise en oeuvre d’un ensemble de mesures compensatoires ciblant l’habitat « roselière » et l’avifaune paludicole à l’échelle de la baie du Mont-Saint-Michel, en lien avec la suppression de roselière lors de travaux de curage du fleuve Couesnon. Le projet a consisté à ouvrir le milieu pour dynamiser la phragmitaie et à constituer des mosaïques d’habitats fonctionnels pour l’avifaune paludicole. Une instruction réglementaire particulièrement lourde a été nécessaire et a inclus la réalisation d’un boisement compensateur sur d’autres terrains. Le chantier s’est déroulé sur deux saisons sèches en 2015 et 2016. Le site a été déboisé par coupe et dessouchage, rognage et évacuation des résidus, terrassement de mares et création d’un accès à la parcelle enclavée. Un suivi écologique reposant sur une méthode standardisée a débuté en 2017. Les premiers résultats sont déjà très encourageants à la fois sur le développement de la phragmitaie, le fonctionnement hydraulique du site et l’accueil des espèces cibles.
Changes in Flexibility and Force are not Different after Static
Versus Dynamic Stretching
Authors: Matsuo Shingo , Iwata Masahiro , Miyazaki Manabu , Fukaya Taizan , Yamanaka Eiji , Nagata Kentaro , Tsuchida Wakako , Asai Yuji , Suzuki Shigeyuki
Published: October 2019

In this study, we examined the effects of static and dynamic stretching on range
of motion (ROM), passive torque (PT) at pain onset, passive stiffness, and
isometric muscle force. We conducted a randomized crossover trial in which 16
healthy young men performed a total of 300 s of active static or dynamic
stretching of the right knee flexors on two separate days in random order. To
assess the effects of stretching, we measured the ROM, PT at pain onset, passive
stiffness during passive knee extension, and maximum voluntary isometric knee
flexion force using an isokinetic dynamometer immediately before and after
stretching. Both static and dynamic stretching significantly increased the ROM
and PT at pain onset (p<0.01) and significantly decreased the passive
stiffness and isometric knee flexion force immediately after stretching
(p<0.01). However, the magnitude of change did not differ between the
two stretching methods for any measurements. Our results suggest that
300 s of either static or dynamic stretching can increase flexibility
and decrease isometric muscle force; however, the effects of stretching do not
appear to differ between the two stretching methods.
A Chemoenzymatic Formal Synthesis of Epoxyquinols A and B
Authors: Collins Jonathan A. , Gerry Christopher J. , Duncan Madeleine M.
Published: October 2019

A formal synthesis of epoxyquinols A and B was completed in nine steps starting from benzoic acid. Enantioselectivity was established through an enzymatic arene dihydroxylation reaction performed by whole cells of Ralstonia eutropha B9 expressing benzoate dioxygenase. Subsequent formation of the enone core was facilitated by a Dauben–Michno-type oxidative transposition of an allylic tertiary alcohol.
Direct Synthesis of N-Functionalized Dipropargylamine Linkers as Models for Use in Peptide Stapling
Authors: Renzetti Andrea , Rutherford Ryan N. , Fukumoto Kozo , Kunciw Dominique , Sore Hannah F. , Spring David R.
Published: October 2019

N-Substituted dipropargylamines that are suitable as functionalized linkers for peptide stapling can be synthesized in one step under mild conditions from commercially available starting materials (41% to quantitative yield).
Free-Hand Pedicle Screw Insertion of Thoracic Spine Using Fennell Technique: Initial Results and Review of Literature
Authors: Satapathy Ayusman , Dash Chinmaya , Sharma Arunav , Sahu Rabi Narayan
Published: October 2019

Aim of the Study This article aims to study the safety and feasibility of Fennell technique of free-hand pedicle screw insertion in thoracic spine.

Methods Consecutive 10 patients in whom 40 thoracic pedicle screw were inserted using Fennell’s technique were included in the study. Postoperative computed tomography scan was done in all the patients. Breach in individual pedicle was analyzed using Gertzbein classification.

Results A total of 40 screws were placed in the thoracic spine in 10 patients by free-hand technique described by Fennell et al. Out of 40 pedicle screws, 26 were placed at the D10 to D12 level, 8 screws were placed at the D7 to D9 level, and 6 screws were placed at the D1 to D6 level. There was one pedicle with grade 1 lateral breach and one pedicle with grade 1 medial breach as per Gertzbein classification. All other screws were contained within the pedicle (Gertzbein grade 0). None of the patients had any added deficits or wound complications in the postoperative period.

Conclusion Thoracic pedicle screw insertion is challenging in nature because of the anatomic variability and proximity of critical structures to the pedicles. Our experience suggests that Fennell technique is a reliable technique, which can be used to place thoracic pedicles consistently, with acceptable rates of pedicle breach. A study involving larger number of patients might prove to establish this technique as an easily reproducible and safe technique for free-hand pedicle screw insertion in thoracic spine.
Multiple cardiac masses and distant metastatic foci in a patient with high grade pleomorphic sarcoma of the heart revealed by follow-up FDG PET/CT
Authors: Uslu L. , Asa S. , Sager S. , Halaç M.
Published: October 2019

Undifferentiated high grade pleomorphic sarcoma of the heart is a rare clinical entity and efficiency of FDG PET/CT in this tumour was not well studied.
Three dimensional ion-acoustic rogons in quantized anisotropic magnetoplasmas with trapped/untrapped electrons
Authors: Irfan M. , Ali S. , El-Tantawy S. A. , Ismaeel Sherif M. E.
Published: October 2019

Three-dimensional (3D) modulational instability (MI) and ion-acoustic (IA) envelopes are studied in a quantized degenerate magnetoplasma, whose constituents are the trapped/untrapped electrons and anisotropic positive ions. By using quantum hydrodynamic equations and the multiscale reductive perturbation technique, a 3D nonlinear Schrödinger equation is derived to account for electron quantization and ion pressure anisotrophy effects. The potential excitations are shown stable (unstable) against the perturbations for Kc<0 (Kc>0), where Kc is a critical parameter that accounts for the longitudinal (transverse) dispersion(s) and nonlinearity effects. Numerically, the nonlinear evolution of IA wavepackets into a 3D MI may be revealed in the ranges of low and high frequencies 0<ω≤0.05 and 0.75≤ω≤1.1. The quantizing magnetic field reduces (enhances) the group speed (wave frequency) of IA excitations, concentrating the wave energy to favor the modulational instability. Finite electronic temperature (viz., Te≤10keV) enhances the untrapped electrons and significantly widens the instability domain Kc>0. The ionic pressure anisotropy increases the wave frequency (ω), piles up the harmonics under Kc>0, and give rise to modulational instability. The quantized magnetic field and anisotropic pressure reduce the amplitude and spatial extension of the IA rogons. This study is important for understanding the 3D MI and unstable excitations in degenerate plasmas, relevant to white dwarfs, neutron stars, and high-energy density experiments, where strong magnetic field quantizes the dynamics of trapped/untrapped electrons.
Asymmetrical voltage response in resonant neurons shaped by nonlinearities
Authors: Pena R. F. O. , Lima V. , Shimoura R. O. , Ceballos C. C. , Rotstein H. G. , Roque A. C.
Published: October 2019

The conventional impedance profile of a neuron can identify the presence of resonance and other properties of the neuronal response to oscillatory inputs, such as nonlinear response amplifications, but it cannot distinguish other nonlinear properties such as asymmetries in the shape of the voltage response envelope. Experimental observations have shown that the response of neurons to oscillatory inputs preferentially enhances either the upper or lower part of the voltage envelope in different frequency bands. These asymmetric voltage responses arise in a neuron model when it is submitted to high enough amplitude oscillatory currents of variable frequencies. We show how the nonlinearities associated to different ionic currents or present in the model as captured by its voltage equation lead to asymmetrical response and how high amplitude oscillatory currents emphasize this response. We propose a geometrical explanation for the phenomenon where asymmetries result not only from nonlinearities in their activation curves but also from nonlinearites captured by the nullclines in the phase-plane diagram and from the system’s time-scale separation. In addition, we identify an unexpected frequency-dependent pattern which develops in the gating variables of these currents and is a product of strong nonlinearities in the system as we show by controlling such behavior by manipulating the activation curve parameters. The results reported in this paper shed light on the ionic mechanisms by which brain embedded neurons process oscillatory information.
Modeling and control methodology for an XYZ micro manipulator
Authors: Tian Yanling , Ma Yue , Lu KangKang , Yang Mingxuan , Zhao Xiaolu , Wang Fujun , Zhang Dawei
Published: October 2019

This paper presents the modeling and control methodology for a piezoactuated compliant XYZ manipulator toward precision positioning. The manipulator was fabricated using a wire electrical discharge machining technique, and the system identification was conducted to obtain the dynamic model based on the frequency response. To reduce the effects of hysteresis, creep, and external disturbances, a feedforward/feedback hybrid controller is proposed, which contains a dynamic dependent Prandtl-Ishlinskii (DDPI) hysteresis model and a novel sliding mode controller. The DDPI hysteresis model has excellent modeling accuracy at high operating frequencies with consideration of the dynamic characteristics of the micromanipulator. The novel sliding mode controller integrated with uncertainty and disturbance estimation (SMCUDE) technique is developed, which has the advantages of fast response, strong robustness, and resistance to chattering. The performance of the DDPI hysteresis model and the novel sliding mode controller is validated and compared using experimental tests. The experimental results indicate that the DDPI model provides better positioning accuracy than the traditional Prandtl-Ishlinskii (P-I) model and the rate-dependent P-I model, and furthermore, the SMCUDE controller can improve the response speed without loss of stability, which demonstrates that precision positioning operations can be implemented by the developed manipulator using the proposed control strategy.
Combining DC and AC electric fields with deterministic lateral displacement for micro- and nano-particle separation
Authors: Calero Victor , Garcia-Sanchez Pablo , Ramos Antonio , Morgan Hywel
Published: October 2019

This paper describes the behavior of particles in a deterministic lateral displacement (DLD) separation device with DC and AC electric fields applied orthogonal to the fluid flow. As proof of principle, we demonstrate tunable microparticle and nanoparticle separation and fractionation depending on both particle size and zeta potential. DLD is a microfluidic technique that performs size-based binary separation of particles in a continuous flow. Here, we explore how the application of both DC and AC electric fields (separate or together) can be used to improve separation in a DLD device. We show that particles significantly smaller than the critical diameter of the device can be efficiently separated by applying orthogonal electric fields. Following the application of a DC voltage, Faradaic processes at the electrodes cause local changes in medium conductivity. This conductivity change creates an electric field gradient across the channel that results in a nonuniform electrophoretic velocity orthogonal to the primary flow direction. This phenomenon causes particles to focus on tight bands as they flow along the channel countering the effect of particle diffusion. It is shown that the final lateral displacement of particles depends on both particle size and zeta potential. Experiments with six different types of negatively charged particles and five different sizes (from 100 nm to 3 μm) and different zeta potential demonstrate how a DC electric field combined with AC electric fields (that causes negative-dielectrophoresis particle deviation) could be used for fractionation of particles on the nanoscale in microscale devices.