bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Synthesis and Characterization of La11+xHg45‐x and RE11Hg44.5 (RE: Nd, Sm) as Hettotypes of the Sm11Cd45 Structure Type
Authors: Tambornino Frank , Schwaerzer Kuno , Hoch Constantin
Published: October 2016

The Hg‐rich amalgams La11,7Hg44,03 (I), Nd11Hg44.5 (II), and Sm11Hg44.5 (III) are prepared by dissolving the lanthanoid metals in a Hg surplus (evacuated glass ampoule, 300 °C, 12 h) followed by removal of excess Hg via distillation.
ChemInform Abstract: Crystal Growth, Structure, and Optical Properties of LiGaGe2Se6.
Authors: Yelisseyev Alexander P. , Isaenko Ludmila I. , Krinitsin Pavel , Liang Fei , Goloshumova Alina A. , Naumov Dmitry Yu. , Lin Zheshuai
Published: October 2016

The title compound is prepared from the elements (750 °C, 2 d) and large single crystals are obtained by the Bridgman‐Stockbarger method.
ChemInform Abstract: Reduction of Manganese Dioxide by Dissolved Lithium in Liquid Ammonia for Li‐Mn‐O Spinels.
Authors: Xu Minwei , Zhang Yin , Que Wenxiu , Song Xiaoping , Zhou Chao , Yang Sen
Published: October 2016

Li1.12Mn1.88O4 spinel is synthesized by reduction of MnO2 by lithium dissolved in liquid ammonia (‐33 °C) and subsequent heat treatment (600—700 °C, 5—10 h).
ChemInform Abstract: Solid Solution Photocatalyst with Spontaneous Polarization Exhibiting Low Recombination Toward Efficient CO2 Photoreduction.
Authors: Zhou Peng , Wang Xin , Yan Shicheng , Zou Zhigang
Published: October 2016

In view of efficient separation of photogenerated carriers, growth of a polar GaN:ZnO solid solution single crystal along its polarization axis is performed by molten salt ion exchange (space group P63mc, powder XRD).
ChemInform Abstract: Two‐Dimensional Inorganic Cationic Network of Thorium Iodate Chloride with Unique Halogen—Halogen Bonds.
Authors: Lu Huangjie , Wang Yaxing , Wang Congzhi , Chen Lanhua , Shi Weiqun , Diwu Juan , Chai Zhifang , Albrecht‐Schmitt Thomas E. , Wang Shuao
Published: October 2016

The new compound [Th3O2(IO3)5(OH)2]Cl is hydrothermally synthesized from an aqueous mixture of Th(NO3)4, HIO3, and KCl (autoclave, 230 °C, 3 d).
ChemInform Abstract: Ruthenium‐Catalyzed Hydroarylation and One‐Pot Twofold Unsymmetrical C—H Functionalization of Arenes.
Authors: Ghosh Koushik , Rit Raja K. , Ramesh E. , Sahoo Akhila K.
Published: October 2016

Methyl phenyl sulfoximine is used as a directing group in the ruthenium‐catalyzed intramolecular hydroarylation of alkene‐tethered benzoic acid derivatives to afford dihydrobenzofurans and indolines.
ChemInform Abstract: Efficient Trapping of 1,2‐Cyclohexadienes with 1,3‐Dipoles.
Authors: Lofstrand Verner A. , West Frederick G.
Published: October 2016

1,2‐Cyclohexadienes are transient intermediates that undergo rapid dimerization and intermolecular trapping with activated olefins and heteroatomic nucleophiles.
ChemInform Abstract: The Highly Selective Metal‐Free Oxidation of Sulfides, Tellurides and Phosphines Using Sodium Bromate in the Presence of Recyclable Ionic Liquid [bmim]HSO4, at 80 °C.
Authors: Rajeswari M. , Lumb Anshika , Khurana Jitender M.
Published: October 2016

A range of sulfones, telluroxides, and phosphine oxides is prepared under metal‐free conditions.
ChemInform Abstract: Tetrahydroxydiboron‐Mediated Palladium‐Catalyzed Transfer Hydrogenation and Deuteriation of Alkenes and Alkynes Using Water as the Stoichiometric H or D Atom Donor.
Authors: Cummings Steven P. , Le Thanh‐Ngoc , Fernandez Gilberto E. , Quiambao Lorenzo G. , Stokes Benjamin J.
Published: October 2016

The hydrogenation of alkenes and alkynes to the corresponding saturated hydrocarbons is achieved in high yields using tetrahydroxydiboron B2(OH)4 as the reagent and water as hydrogen source.
ChemInform Abstract: Copper‐Mediated Aromatic 1,1‐Difluoroethylation with (1,1‐Difluoroethyl)trimethylsilane (TMSCF2CH3).
Authors: Li Xinjin , Zhao Jingwei , Wang Yunze , Rong Jian , Hu Mingyou , Chen Dingben , Xiao Pan , Ni Chuanfa , Wang Limin , Hu Jinbo
Published: October 2016

The practical title reaction tolerates various functional groups, including complex steroids.
ChemInform Abstract: Eosin Y (EY) Photoredox‐Catalyzed Sulfonylation of Alkenes: Scope and Mechanism.
Authors: Meyer Andreas Uwe , Strakova Karolina , Slanina Tomas , Koenig Burkhard
Published: October 2016

Alkyl‐ and aryl vinyl sulfones are obtained by eosin Y (EY)‐mediated visible‐light photooxidation of sulfinate salts and reaction of the resulting S‐centered radicals with alkenes.
ChemInform Abstract: Intramolecular Oxidative Palladium‐Catalyzed Diamination Reactions of Alkenyl Sulfamates: An Efficient Synthesis of [1,2,5]Thiadiazolo‐fused Piperazinones.
Authors: Chiacchio Ugo , Broggini Gianluigi , Romeo Roberto , Gazzola Silvia , Chiacchio Maria A. , Giofre Salvatore V. , Gabriele Bartolo , Mancuso Raffaella , Floresta Giuseppe , Zagni Chiara
Published: October 2016

An intramolecular diamination of N‐allylic glycine‐derived sulfamates leads to thiadiazolo‐fused piperazinones in good yields.
ChemInform Abstract: Visible‐Light‐Induced Photocatalytic Azotrifluoromethylation of Alkenes with Aryldiazonium Salts and Sodium Triflinate.
Authors: Yu Xing‐Long , Chen Jia‐Rong , Chen Dong‐Zhen , Xiao Wen‐Jing
Published: October 2016

The reaction tolerates variously functionalized aryl diazonium salts as well as terminal, 1,1‐ and cyclic or acyclic 1,2‐disubstituted alkenes.
ChemInform Abstract: One‐Pot Synthesis of α‐Amino Acids Through Carboxylation of Ammonium Ylides with CO2 Followed by Alkyl Migration.
Authors: Mita Tsuyoshi , Sugawara Masumi , Sato Yoshihiro
Published: October 2016

The method comprises four efficient consecutive transformations, namely ammonium salt formation, carboxylation, esterification and alkyl migration in a simple one‐pot manner.
ChemInform Abstract: Silver‐Mediated anti‐Markovnikov and Markovnikov‐Selective Hydrotrifluoromethylthiolation of Terminal Alkynes.
Authors: Wu Wei , Dai Wenpeng , Ji Xinfei , Cao Song
Published: October 2016

The direct oxidative hydrotrifluoromethylthiolation of terminal alkynes yields vinyl trifluoromethyl thioethers as anti‐Markovnikov and Markovnikov adducts in moderate to good yields depending on the reaction conditions.
ChemInform Abstract: Dearomatizing Spirocyclization Reactions of Alkynyl Cyanamides.
Authors: Singh Ravi P. , Spears Jada A. , Dalipe Alfonso , Yousufuddin Muhammed , Lovely Carl J.
Published: October 2016

Propargylic cyanamide (I) is found to be a competent substrate in the electrophile‐initiated dearomatizing spirocyclization with halogens, sulfur and selenium reagents.
ChemInform Abstract: Friedel—Crafts Alkylation of Arenes with 2‐Halogeno‐2‐CF3‐styrenes under Superacidic Conditions. Access to Trifluoromethylated Ethanes and Ethenes.
Authors: Sandzhieva Maria A. , Kazakova Anna N. , Boyarskaya Irina A. , Ivanov Alexandr Yu. , Nenajdenko Valentine G. , Vasilyev Aleksander V.
Published: October 2016

The hydroarylation reaction proceeds via benzyl cations formed under protonation in a superacid as proved by NMR spectroscopy and theoretical DFT calculations.
ChemInform Abstract: Synthesis of Indole‐Substituted Indanones via Palladium(II)‐Catalyzed Tandem Reaction of ortho‐Electron‐Deficient Alkynyl‐Substituted Aryl Aldehydes with Indoles.
Authors: Zhang Jianbo , Han Xiuling , Lu Xiyan
Published: October 2016

This efficient and economical cyclization reaction of ortho‐alkynyl aromatic aldehydes with indoles provides indolylindanones.
ChemInform Abstract: Discogens Possessing Aryl Side Groups Synthesized by Suzuki Coupling of Triphenylene Triflates and Their Self‐Organization Behavior.
Authors: Zhao Ke‐Qing , Gao Yue , Yu Wen‐Hao , Hu Ping , Wang Bi‐Qin , Heinrich Benoit , Donnio Bertrand
Published: October 2016

Pd‐catalyzed Suzuki cross‐coupling reactions between arylboronic acids and bromoarenes is applied in the synthesis of liquid‐crystalline materials.
ChemInform Abstract: 1‐Methylimidazolium Trifluoroacetate Efficiently Catalyzed Three Component Synthesis of Diazaspiro[5.5]undecane‐1,5,9‐trione Derivatives under Solvent‐Free Conditions
Authors: Xu Zhaohui , Zhang Houfu , Lin Chunhua , Liu Deyong
Published: October 2016

by reaction of various aromatic aldehydes with urea and dioxanedione
ChemInform Abstract: Acid‐Catalyzed Ring‐Opening Cyclization of Spirocyclopropanes for the Construction of a 2‐Arylbenzofuran Skeleton: Total Synthesis of Cuspidan B.
Authors: Nambu Hisanori , Ono Naoki , Yakura Takayuki
Published: October 2016

The utility of this method is demonstrated in the first total synthesis of cuspidan B (V).
ChemInform Abstract: Transition‐Metal‐Free TBAI‐Facilitated Addition—Cyclization of N‐Methyl‐N‐arylacrylamides with Arylaldehydes or Benzenesulfonohydrazides: Access to Carbonyl‐ and Sulfone‐Containing N‐Methyloxindoles.
Authors: Ji Peng‐Yi , Zhang Ming‐Zhong , Xu Jing‐Wen , Liu Yu‐Feng , Guo Can‐Cheng
Published: October 2016

In comparison to previously developed methods, the presented protocol offers a safe and environmentally friendly approach to carbonyl and sulfone‐containing oxindoles in moderate to high yields.
ChemInform Abstract: Aerobic Radical‐Cascade Alkylation/Cyclization of α,β‐Unsaturated Amides: An Efficient Approach to Quaternary Oxindoles.
Authors: Biswas Promita , Paul Subhasis , Guin Joyram
Published: October 2016

An unprecedented method for the aerobic radical alkylarylation of electron‐deficient amides through dual C—H functionalization under metal‐ and peroxide‐free conditions is presented.
ChemInform Abstract: Regioselective Synthesis of Pyrazole and Pyridazine Esters from Chalcones and α‐Diazo‐β‐ketoesters.
Authors: Nair Deepa , Pavashe Prashant , Katiyar Savita , Namboothiri Irishi N.N.
Published: October 2016

Base mediated deacylation of title compounds (II) generates diazoester anion, a reactive 1,3‐dipol, which undergoes [3 + 2] annulation with chalcones (I) to afford pyrazole ketoesters (III).
ChemInform Abstract: Synthesis of Oxazolidinones from Epoxides and Isocyanates Catalyzed by Aluminium Heteroscorpionate Complexes.
Authors: Castro‐Osma Jose A. , Earlam Amy , Lara‐Sanchez Agustin , Otero Antonio , North Michael
Published: October 2016

The reaction has a broad substrate scope, thus tolerating functionalized aryl and alkyl substituted epoxides and arylisocyanates, but no alkyl isocyanates.
ChemInform Abstract: Sustainable Synthesis of 2‐Arylbenzoxazoles over a Cobalt‐Based Nanocomposite Catalyst.
Authors: He Jian , Lin Fu , Yang Xufang , Wang Di , Tan Xiaohua , Zhang Shujun
Published: October 2016

The new cobalt‐based heterogeneous catalyst is prepared by adsorbing in situ produced nitrogen‐ligated cobalt(II) acetate complexes on commercially available SiO2 and subsequent pyrolysis at 800 °C for 2 h under N2 atmosphere.
ChemInform Abstract: Design, Synthesis and Characterization of New 1,2,3‐Triazolyl Pyrazole Derivatives as Potential Antimicrobial Agents via a Vilsmeier—Haack Reaction Approach.
Authors: Bhat Manjunatha , Nagaraja G. K. , Kayarmar Reshma , Peethamber S. K. , Shafeeulla R. Mohammed
Published: October 2016

Some of the title pyrazole derivatives are found to be potent and broad spectrum antibacterial agents.
ChemInform Abstract: The Study of [4 + 2] Cycloaddition Reactions of Some Unactivated Aldehydes with a Simple Diene: Role of Various Iron(III) Porphyrins as Catalysts.
Authors: Singh Manoj Kumar , Kumar Manoj , Bandyopadhyay Debkumar
Published: October 2016

The [4+2] cycloaddition reaction of aromatic aldehydes with 2,3‐dimethyl‐1,3‐butadiene catalyzed by various iron(III) porphyrins is studied.
ChemInform Abstract: Efficient Access to Alkynylated Quinalizinones via the Gold(I)‐Catalyzed Aminoalkynylation of Alkynes.
Authors: Shinde Popat S. , Shaikh Aslam C. , Patil Nitin T.
Published: October 2016

Further derivatization of the products via Sonogashira‐coupling or azide‐alkyne cycloaddition of the alkyne moiety is demonstrated.
ChemInform Abstract: Nano‐CuCr2O4: An Efficient Catalyst for a One‐Pot Synthesis of Tetrahydrodipyrazolopyridine.
Authors: Shahbazi‐Alavi Hossein , Safaei‐Ghomi Javad , Eshteghal Fahime , Zahedi Safura , Nazemzadeh Seyed Hadi , Alemi‐Tameh Fatemeh , Tavazo Maryam , Basharnavaz Hadi , Lashkari Mohammad Rasool
Published: October 2016

The title compounds are prepared by multicomponent cyclocondensation of ethyl acetoacetate, benzaldehydes, ammonium acetate, and hydrazine hydrate in short times and with good to high yields.
ChemInform Abstract: Samarium‐Mediated Intramolecular Cross‐Couplings of an α,β‐Unsaturated N‐Acylpyrrole.
Authors: Law Katherine R. , McErlean Christopher S. P.
Published: October 2016

Title compound (I) is shown to be a suitable substrate for SmI2‐mediated reductive cyclization to give a trans,syn,trans‐fused tetrahydropyran (II).
ChemInform Abstract: Catalytic Asymmetric [3 + 3] Annulation of Cyclopropanes with Mercaptoacetaldehyde.
Authors: Fu Xuan , Lin Lili , Xia Yong , Zhou Pengfei , Liu Xiaohua , Feng Xiaoming
Published: October 2016

The highly diastereoselective and enantioselective title reaction of aryl substituted cyclopropyl ketones with mercaptoacetaldehyde is described.
ChemInform Abstract: Zn‐Catalyzed Hydrohydrazination of Propargylamides with BocNHNH2: A Novel Entry into the 1,2,4‐Triazine Core.
Authors: Lukin Alexey , Vedekhina Tatiana , Tovpeko Dmitry , Zhurilo Nikolay , Krasavin Mikhail
Published: October 2016

The convenient one‐pot protocol allows the synthesis of triazines via a sequential hydroazination/cyclodehydration/oxidation process.
ChemInform Abstract: Gold(I)‐Catalyzed Azepine Synthesis from Propargyl Acetals and Aryl Azides.
Authors: Evjen Sigvart , Fiksdahl Anne
Published: October 2016

The reaction proceeds by a sequential two‐step pathway via an activated Z‐2‐methoxy vinyl imine intermediate, with a final [4+3] cycloaddition.
ChemInform Abstract: Asymmetric Aza‐Morita—Baylis—Hillman Reactions of Chiral N‐Phosphonyl Imines with Acrylates via GAP Chemistry/Technology.
Authors: Yang Bing , Ji Xiaozhou , Xue Yunsheng , Zhang Haowei , Shen Minxing , Jiang Bo , Li Guigen
Published: October 2016

The atom‐economical reaction proceeds with excellent diastereo and enantioselectivity.
ChemInform Abstract: Asymmetric Syntheses of (+)‐Preussin B, the C(2)‐Epimer of (‐)‐Preussin B, and 3‐Deoxy‐(+)‐preussin B.
Authors: Buchman Marek , Csatayova Kristina , Davies Stephen G. , Fletcher Ai M. , Houlsby Ian T. T. , Roberts Paul M. , Rowe Sam M. , Thomson James E.
Published: October 2016

Efficient de novo asymmetric syntheses of the title antifungal alkaloids are described.
ChemInform Abstract: Flexible Total Synthesis of (.+‐.)‐Aureothin, a Potent Antiproliferative Agent.
Authors: Henrot Matthias , Jean Alexandre , Peixoto Philippe A. , Maddaluno Jacques , De Paolis Michael
Published: October 2016

The synthesis of (.+‐.)‐aureothin (I) as well as imino (Ib,c) or keto group (Id) derivatives thereof is presented.
ChemInform Abstract: Synthesis, Characterization, and Properties of Metal Phosphide Catalysts for the Hydrogen‐Evolution Reaction
Authors: Callejas Juan F. , Read Carlos G. , Roske Christopher W. , Lewis Nathan S. , Schaak Raymond E.
Published: October 2016

Review: 200 refs.
ChemInform Abstract: Role of Metal Oxide Electron‐Transport Layer Modification on the Stability of High Performing Perovskite Solar Cells
Authors: Singh Trilok , Singh Jai , Miyasaka Tsutomu
Published: October 2016

Review: 80 refs.
ChemInform Abstract: Novel Properties and Potential Applications of Functional Ligand‐Modified Polyoxotitanate Cages
Authors: Li Ning , Matthews Peter D. , Luo He‐Kuan , Wright Dominic S.
Published: October 2016

Review: 72 refs.
ChemInform Abstract: Recent Developments for the Photoinduced Ar—X Bond Dissociation Reaction
Authors: Qiu Guanyinsheng , Li Yuewen , Wu Jie
Published: October 2016

Review: 56 refs.
ChemInform Abstract: Recent Advances in Copper‐Mediated Chelation‐Assisted Functionalization of Unactivated C—H Bonds
Authors: Rao Wei‐Hao , Shi Bing‐Feng
Published: October 2016

Review: 70 refs.
ChemInform Abstract: Synthesis and Applications of Fluorous Phosphines
Authors: Law Chung‐kay Edwin , Horvath Istvan T.
Published: October 2016

Review: 63 refs.
ChemInform Abstract: Recent Developments in Intermolecular Radical Arylations of Arenes and Heteroarenes
Authors: Hofmann Josefa , Heinrich Markus R.
Published: October 2016

Review: [77 refs.
ChemInform Abstract: Iridium‐Catalyzed Diastereo‐, Enantio‐, and Regioselective Allylic Alkylation with Prochiral Enolates
Authors: Hethcox J. Caleb , Shockley Samantha E. , Stoltz Brian M.
Published: October 2016

Review: 33 refs.
ChemInform Abstract: Catalytic Asymmetric Reactions with N,O‐Aminals
Authors: Huang Yi‐Yong , Cai Chen , Yang Xing , Lv Zong‐Chao , Schneider Uwe
Published: October 2016

Review: 179 refs.
ChemInform Abstract: Synthetic Approaches to Trifluoromethoxy‐Substituted Compounds
Authors: Tlili Anis , Toulgoat Fabien , Billard Thierry
Published: October 2016

Review: [62 refs.
ChemInform Abstract: Ring‐Opening Reactions of Oxetanes: A Review of Methodology Development and Synthetic Applications
Authors: Ahmad Sajjad , Yousaf Muhammad , Mansha Asim , Rasool Nasir , Zahoor Ameer Fawad , Hafeez Freeha , Rizvi Sayyad Muhammad Ali
Published: October 2016

Review: 53 refs.
ChemInform Abstract: B=N Units as Part of Extended π‐Conjugated Oligomers and Polymers
Authors: Helten Holger
Published: October 2016

Review: [39 refs.
ChemInform Abstract: 3D Self‐Supporting Porous Magnetic Assemblies for Water Remediation and Beyond
Authors: Du Ran , Zhao Qiuchen , Zheng Zhe , Hu Wenping , Zhang Jin
Published: October 2016

Review: 140 refs.
ChemInform Abstract: Importance and Challenges of Electrochemical in Situ Liquid Cell Electron Microscopy for Energy Conversion Research
Authors: Hodnik Nejc , Dehm Gerhard , Mayrhofer Karl J. J.
Published: October 2016

Review: 93 refs.
Isolation and Identification of Two Novel Alkaligenous Arsenic(III)‐Oxidizing Bacteria From a Realgar Mine, China
Authors: Yang Zhihui , Liu Yi , Liao Yingping , Chai Liyuan , Li Qingzhu , Liao Qi
Published: October 2016

Two novel As(III)‐oxidizing bacterial strains were isolated from highly arsenic‐contaminated (2938.6 mg/kg) soils. The phylogenetic tree based on the bacterial 16S rRNA sequences indicated that the two strains were closely related to Brevibacterium yomogidense and Bacillus beijingensis strain YMD‐2, respectively, and were therefore named Brevibacterium sp. YZ‐1 (YZ‐1) and Bacillus beijingensis YZ‐2 (YZ‐2). The strains YZ‐1 and YZ‐2 with vigorous tolerance to As(III) (1500 mg/L) can oxidize 73.5 and 66 mg/L As(III) in 72 h, respectively. Moreover, the two strains were alkaligenous and YZ‐2 increased the pH in the culture medium more effectively than YZ‐1 in 3 days. The optimum culture initial pH and temperature to oxidize As(III) were 8 and 30–31°C, respectively. The results indicate that it is promising to develop a cost‐effective and eco‐friendly bioremediation strategy to alkaline arsenic‐contaminated soils with the two strains, Brevibacterium sp. YZ‐1 and B. beijingensis YZ‐2.
Impact of chronic disease on emotional distress in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
Authors: Vuotto Stefanie C. , Krull Kevin R. , Li Chenghong , Oeffinger Kevin C. , Green Daniel M. , Patel Sunita K. , Srivastava Deokumar , Stovall Marilyn , Ness Kirsten K. , Armstrong Gregory T. , Robison Leslie L. , Brinkman Tara M.
Published: October 2016

BACKGROUND

The current study was performed to examine associations between childhood cancer therapies, chronic health conditions, and symptoms of emotional distress in adult survivors of childhood cancer.

METHODS

Participants included 5021 adult survivors of childhood cancer (mean age, 32.0 years [standard deviation, 7.6 years] with a time since diagnosis of 23.2 years [standard deviation, 4.5 years]) who completed measures assessing symptoms of anxiety, depression, and posttraumatic stress. Cardiac, pulmonary, and endocrine conditions were graded using the National Cancer Institute Common Terminology Criteria for Adverse Events (version 4.03; grades 1‐4). Structural equation modeling was used to examine hypothesized pathways between cancer treatment exposures, chronic health conditions, and symptoms of emotional distress. Multivariable models were used to estimate relative risks (RRs) for associations between chronic health conditions and distress.

RESULTS

Survivors with cardiovascular, endocrine, or pulmonary conditions were found to have a significantly higher prevalence of emotional distress symptoms. In path analyses and multivariable models, significant effects were observed between endocrine (β = .12 [P = .002] and RR, 1.3 [95% confidence interval (95% CI), 1.1‐1.6]) and pulmonary (β = .13 [P<.001] and RR, 1.4 [95% CI, 1.1‐1.7]) conditions and depression, and between cardiac (β = .13 [P = .001] and RR, 1.5 [95% CI, 1.2‐1.8]) and pulmonary (β = .15 [P<.001] and RR, 1.6 [95% CI, 1.3‐2.0]) conditions and anxiety. All treatment‐related chronic health conditions were found to be associated with posttraumatic stress symptoms (cardiac: β = .09 [P = .004] and RR, 1.3 [95% CI, 1.2‐1.5]; endocrine: β = .12 [P<.001] and RR, 1.3 [95% CI, 1.2‐1.5]; and pulmonary: β = .13 [P<.001] and RR, 1.4 [95% CI, 1.2‐1.6]).

CONCLUSIONS

Chronic health conditions resulting from childhood cancer therapies contribute to emotional distress in adult survivors. Targeted mental health screening efforts in this at‐risk population appear warranted. Therapeutic approaches should consider the complex interplay between chronic health conditions and symptoms of emotional distress. Cancer 2017;123:521–528. © 2016 American Cancer Society.
Enzymatic Bioelectrosynthetic Ammonia Production: Recent Electrochemistry of Nitrogenase, Nitrate Reductase, and Nitrite Reductase
Authors: Milton Ross D. , Minteer Shelley D.
Published: October 2016

As an essential component of amino acids and nucleic acids, nitrogen (N) is a key element of life. For atmospheric (dinitrogen, N2) and environmental (nitrate and nitrite, NO3− and NO2−) sources of N to be utilized in amino acid synthesis in various forms of life, it must first be reduced to ammonia (NH3). The Haber–Bosch process, in which N2 is reduced to NH3 at elevated temperature and pressure, represents a major NH3 production process that has had a great impact on the agricultural crop industry. This Minireview discusses the recent electrochemistry of three key enzymes of the global biogeochemical N cycle (nitrogenase, nitrate reductase, and nitrite reductase), in view of moving toward the creation of alternative NH3 production biotechnologies.
Feasibility and Acceptability of the ‘HABIT’ Group Programme for Comorbid Bipolar and Alcohol and Substance use Disorders
Authors: Biseul Isabelle , Icick Romain , Seguin Perrine , Bellivier Frank , Scott Jan
Published: October 2016

Objectives

We investigated the feasibility and acceptability of an integrated group therapy (called HABIT) for comorbid bipolar disorder (BD) and alcohol and substance use disorders (ASUD) (BD‐ASUD), a disabling clinical presentation for which no specific treatment has been validated. The 14‐session HABIT programme employs psychoeducation‐oriented cognitive‐behaviour therapy (CBT) followed by mindfulness‐based relapse prevention (MBRP) therapy.

Method

Potential group participants were recruited from adult clients with a DSM‐IV diagnosis of BD and an ASUD who were referred by their treating clinician. Observer‐rated changes in mood symptoms and ASUD, attendance rates and subjective feedback are reported.

Results

Eight of 12 clients referred to the programme initially agreed to join the group, six attended the first group session and five clients completed the programme. Group mean scores for mood symptoms improved over time, with slightly greater reductions in depression during the first module. About 50% of individuals showed clinically significant improvement (≥30% reduction) in alcohol and substance use. Attendance rates showed some variability between individuals and across sessions, but the average attendance rate of the group was marginally higher for the first module (86%) as compared with the second module (77%). Most clients reported high levels of general satisfaction with a group specifically targeted at individuals with BD‐ASUD.

Conclusion

This small pilot study suggests our intensive group therapy is acceptable and feasible. If findings are replicated, we may have identified a therapy that, for the first time, leads to improvement in both mood and substance use outcomes in clients with difficult‐to‐treat comorbid BD‐ASUD. Copyright © 2016 John Wiley & Sons, Ltd.

Key Practitioner Message

Comorbidity between bipolar and alcohol and substance use disorders (BD‐ASUD) is frequent and highly disabling;

Therapeutic research on approaches that can simultaneously help BD and ASUD is lacking;

Previous research highlights the need for integrated treatment of both conditions but showed improvements limited to either element of the comorbid disorder;

This pilot study supports the feasibility and acceptability of an intensive, 14‐session group therapy programme that integrates CBT and mindfulness approaches.
Don't Forget Product Recovery in Catalysis Research—Check the Distillation Resistance
Authors: Lange Jean‐Paul
Published: October 2016

When investigating a new catalytic reaction, scientists may wonder if the crude reaction product can be easily separated and purified. We present here a new concept—distillation resistance—to assess the potential of distillation as a purification technique and to guide catalyst formulation or operation at the very early stage of the research. Distillation resistance, which has been developed from the analysis of 15 industrial distillation trains, can be quickly calculated with knowledge of only the product composition and atmospheric boiling points of the components. It can be directly converted into a preliminary distillation cost that considers investment and energy cost. Its application and its potential guidance in catalysis research are illustrated through a few cases studies derived from biorefinery processes.
Cool habitats support darker and bigger butterflies in Australian tropical forests
Authors: Xing Shuang , Bonebrake Timothy C. , Tang Chin Cheung , Pickett Evan J. , Cheng Wenda , Greenspan Sasha E. , Williams Stephen E. , Scheffers Brett R.
Published: October 2016

Morphology mediates the relationship between an organism's body temperature and its environment. Dark organisms, for example, tend to absorb heat more quickly than lighter individuals, which could influence their responses to temperature. Therefore, temperature‐related traits such as morphology may affect patterns of species abundance, richness, and community assembly across a broad range of spatial scales. In this study, we examined variation in color lightness and body size within butterfly communities across hot and cool habitats in the tropical woodland–rainforest ecosystems of northeast Queensland, Australia. Using thermal imaging, we documented the absorption of solar radiation relative to color lightness and wingspan and then built a phylogenetic tree based on available sequences to analyze the effects of habitat on these traits within a phylogenetic framework. In general, darker and larger individuals were more prevalent in cool, closed‐canopy rainforests than in immediately adjacent and hotter open woodlands. In addition, darker and larger butterflies preferred to be active in the shade and during crepuscular hours, while lighter and smaller butterflies were more active in the sun and midday hours—a pattern that held after correcting for phylogeny. Our ex situ experiment supported field observations that dark and large butterflies heated up faster than light and small butterflies under standardized environmental conditions. Our results show a thermal consequence of butterfly morphology across habitats and how environmental factors at a microhabitat scale may affect the distribution of species based on these traits. Furthermore, this study highlights how butterfly species might differentially respond to warming based on ecophysiological traits and how thermal refuges might emerge at microclimatic and habitat scales.
Classification of California streams using combined deductive and inductive approaches: Setting the foundation for analysis of hydrologic alteration
Authors: Pyne Matthew I. , Carlisle Daren M. , Konrad Cristopher P. , Stein Eric D.
Published: October 2016

Regional classification of streams is an early step in the Ecological Limits of Hydrologic Alteration framework. Many stream classifications are based on an inductive approach using hydrologic data from minimally disturbed basins, but this approach may underrepresent streams from heavily disturbed basins or sparsely gaged arid regions. An alternative is a deductive approach, using watershed climate, land use, and geomorphology to classify streams, but this approach may miss important hydrological characteristics of streams. We classified all stream reaches in California using both approaches. First, we used Bayesian and hierarchical clustering to classify reaches according to watershed characteristics. Streams were clustered into seven classes according to elevation, sedimentary rock, and winter precipitation. Permutation‐based analysis of variance and random forest analyses were used to determine which hydrologic variables best separate streams into their respective classes. Stream typology (i.e., the class that a stream reach is assigned to) is shaped mainly by patterns of high and mean flow behavior within the stream's landscape context. Additionally, random forest was used to determine which hydrologic variables best separate minimally disturbed reference streams from non‐reference streams in each of the seven classes. In contrast to stream typology, deviation from reference conditions is more difficult to detect and is largely defined by changes in low‐flow variables, average daily flow, and duration of flow. Our combined deductive/inductive approach allows us to estimate flow under minimally disturbed conditions based on the deductive analysis and compare to measured flow based on the inductive analysis in order to estimate hydrologic change.
Planktonic equatorial diversity troughs: fact or artifact? Latitudinal diversity gradients in Radiolaria
Authors: Boltovskoy Demetrio , Correa Nancy
Published: October 2016

In contrast to the classical notion of an increasing biodiversity from the poles to the equator, a number of studies concluded that the diversity of marine species is highest at the middle latitudes, and decreases at the equator. Using a worldwide database critically compiled from 72 surveys (307 species, 4,807 water column and surface sediment samples), we analyzed the latitudinal gradients in species richness (LGSR) of a highly diversified group of marine holoplanktonic protists, the polycystine Radiolaria. Species richness values were corrected for uneven sample coverage and sample size, and contrasted with gradients in 11 environmental variables. Radiolarian species richness decreases from the equator to the poles both in the water column and in the surface sediments and is tightly coupled with temperature throughout the entire thermal range of marine waters. In the tropical Pacific Ocean, a conspicuous east‐west gradient in diversity is also associated with temperature. Globally, diversity is negatively correlated with mean annual concentrations of nutrients (N, P, Si) and chlorophyll a. Disagreements with results reported for many other oceanic plankton may stem from the reduction of 3D distributional patterns onto 2D or 1D spaces, to the intermittent mixing of Subtropical and Subpolar species at the middle latitudes, and to a Mid‐Domain Effect. The fact that radiolarian LGSR do not show this drop at the equator is partly due to methodological and database‐related differences, and probably also in part a reflection of taxon‐specific traits.
Controlled Voltage Source Vector Control for Switched Reluctance Motors Using PWM Method
Authors: NAKAO NORIYA , AKATSU KAN
Published: October 2016

This paper proposes controlled voltage source vector control for switched reluctance motors using the pulse width modulation method. This proposed technique can achieve high controllability for variable speed drives, low current ripple and low noise operation, and high motor efficiency at high speed. Moreover, its implementation is easy because the controller design does not require complicated offline data such as the magnetization characteristics. To verify the effectiveness, an experiment was conducted to compare the performances of the proposed technique and a conventional unipolar drive using the hysteresis comparator method.
Experimental Verification for Practical Application of Inductive Power Transfer System for Railway
Authors: SHIMODE DAISUKE , MURAI TOSHIAKI , SAWADA TADASHI
Published: October 2016

Inductive Power Transfer systems (IPT systems) for moving Electrical Vehicles (EVs) are often discussed. However, an IPT system for moving railway vehicles has not been sufficiently examined. In order to employ the IPT system for railway vehicles, this paper examines the characteristics of railway IPT systems, such as efficiency, temperature rise, and durability. Because the required characteristics of the IPT system for railway are different from those of EV, one example of a railway IPT system is proposed, and the verification items for practical use are examined. Moreover, we manufactured test equipment that can imitate the field environment in order to verify these items before practical use in the field. The test procedure and test results demonstrate the possibility of practical use of a railway IPT system.
Performance of Dead‐Time Compensation Methods in Three‐Phase Grid‐Connection Converters
Authors: MANNEN TOMOYUKI , FUJITA HIDEAKI
Published: October 2016

This paper discusses the performance of compensation methods for dead‐time voltage error in voltage‐source grid‐connection pulse‐width modulation converters. The theoretical analysis in this paper reveals the relationship between the voltage error and the current ripples through the converter. The analytical results imply that the voltage error is strongly affected by the amplitude of the current ripples as well as the source power factor. This paper proposes a new compensation method which makes it possible to use two lookup tables to reduce the calculation time in the controller. The compensation characteristics are compared by using a 200‐V 5‐kW three‐phase grid‐connection converter. As a result, conventional approximation‐based compensation methods exhibit an acceptable performance in a restricted power‐factor operation range. In contrast, the turn‐off transition‐based compensation method and the proposed method have a good compensation performance all over the power factor.
Phthalocyanine Derivatives with Eight Peripheral Long‐Chain n‐Alkylseleno Substituents
Authors: Reintanz Philipp M. , Guthardt Robin , Bruhn Clemens , Mohr Fabian , Siemeling Ulrich
Published: October 2016

4,5‐Bis(n‐octylseleno)phthalodinitrile and 4,5‐bis(n‐dodecylseleno)phthalodinitrile were efficiently synthesised from 4,5‐dichlorophthalodinitrile and the corresponding selenolate RSeMgBr (prepared in situ from elemental selenium and RMgBr; R = n‐octyl, n‐dodecyl). Lithium chloride was essential for achieving the substitution of both chloro substituents. The crystal structures of the monosubstitution product 4‐chloro‐5‐n‐octylselenophthalodinitrile and both disubstitution products were determined by single‐crystal X‐ray diffraction, with that of 4,5‐bis(n‐dodecylseleno)phthalodinitrile exhibiting intermolecular C–H···Se contacts compatible with hydrogen bonds. Cyclotetramerisation of these 4,5‐bis(n‐alkylseleno)phthalodinitriles under Tomoda conditions afforded the corresponding 2,3,9,10,16,17,23,24‐octakis(n‐alkylseleno)phthalocyanines PcSeRH2 (R = n‐octyl, n‐dodecyl). The phthalocyaninatomanganese(III) complexes [MnCl(PcSeR)] were obtained from the cyclotetramerisation in the presence of manganese(II) chloride after aerobic workup. The use of terbium(III) chloride as metal salt in the cyclotetramerisation furnished the “double‐decker” complexes [Tb(PcSeR)2].
Synthesis and Biological Evaluation of Migrastatin Macrotriazoles
Authors: Gabba Adele , Robakiewicz Stefania , Taciak Bartłomiej , Ulewicz Katarzyna , Broggini Gianluigi , Rastelli Giulio , Krol Magadalena , Murphy Paul V. , Passarella Daniele
Published: October 2016

The synthesis of three macrotriazoles that are analogues of migrastatin is reported. The synthesis is based on copper(I)‐ and ruthenium‐catalyzed azide–alkyne cycloaddition reactions. The enantiopure terminal alkyne derivatives were prepared by using the Trost desymmetrization, Brown alkoxyallylation and an efficient Colvin reaction. Biological evaluation of the products revealed a promising efficiency in reducing the ability of MDA‐MB‐361 cell lines to migrate.
Missing data imputation for paired stream and air temperature sensor data
Authors: Li Han , Deng Xinwei , Smith Eric
Published: October 2016

Stream water temperature is an important factor in determining the impact of climate change on hydrologic systems. Near continuous monitoring of air and stream temperatures over large spatial scales is possible due to inexpensive temperature recorders. However, missing water temperature data commonly occur due to the failure or loss of equipment. Missing data creates difficulties in modeling relationships between air and stream water temperatures. It also imposes challenges if the objective is an analysis, for example, clustering streams in terms of the effect of changes in water temperature. In this work, we propose to use a novel spatial–temporal varying coefficient model to impute missing water temperatures. Modeling the relationship between air and water temperature over time and space increases the effectiveness of imputing the missing water temperatures. A parameter estimation method is developed, which utilizes the temporal covariation in the relationship, borrows strength from neighboring stream sites, and is useful for imputing sequences of missing data. A simulation study is conducted to examine the performance of the proposed method in comparison with several existing imputation methods. The proposed method is applied to cluster streams with missing water temperatures into groups from 156 streams with meaningful interpretations.
Stormy geomorphology: an introduction to the Special Issue
Authors: Spencer Tom , Naylor Larissa , Lane Stuart , Darby Stephen , Macklin Mark , Magilligan Francis , Möller Iris
Published: October 2016

The degree to which the climate change signal can be seen in the increasing frequency and/or magnitude of extreme events forms a key part of the global environmental change agenda. Geomorphology engages with this debate through extending the instrumental record with palaeogeomorphological research; studying resilience and recovery of geomorphic systems under extreme disturbance; documenting the mediation by catchment organisation of transport processes during extreme events; applying new monitoring methods to better understand process‐response systems; and illustrating how process, experimental and modelling insights can be used to define the buffering of geomorphic systems and human assets from the effects of extremes, providing practical outcomes for practitioners. Copyright © 2016 John Wiley & Sons, Ltd.
Cessation of oil exposure in harlequin ducks after the Exxon Valdez oil spill: Cytochrome P4501A biomarker evidence
Authors: Esler Daniel , Ballachey Brenda E. , Bowen Lizabeth , Miles A. Keith , Dickson Rian D. , Henderson John D.
Published: October 2016

The authors quantified hepatic hydrocarbon-inducible cytochrome P4501A (CYP1A) expression, as ethoxyresorufin-O-deethylase (EROD) activity, in wintering harlequin ducks (Histrionicus histrionicus) captured in Prince William Sound, Alaska (USA), during 2011, 2013, and 2014 (22–25 yr following the 1989 Exxon Valdez oil spill). Average EROD activity was compared between birds from areas oiled by the spill and those from nearby unoiled areas. The present study replicated studies conducted from 1998 to 2009 demonstrating that harlequin ducks using areas oiled in 1989 had elevated EROD activity, indicative of oil exposure, up to 2 decades post spill. In the present study, it was found that average EROD activity during March 2011 was significantly higher in wintering harlequin ducks captured in oiled areas relative to unoiled areas, which the authors interpret to indicate that harlequin ducks continued to be exposed to residual Exxon Valdez oil up to 22 yr after the original spill. However, the 2011 results also indicated reductions in exposure relative to previous years. Average EROD activity in birds from oiled areas was approximately 2 times that in birds from unoiled areas in 2011, compared with observations from 2005 to 2009, in which EROD activity was 3 to 5 times higher in oiled areas. It was also found that average EROD activity during March 2013 and March 2014 was not elevated in wintering harlequin ducks from oiled areas. The authors interpret these findings to indicate that exposure of harlequin ducks to residual Exxon Valdez oil abated within 24 yr after the original spill. The present study finalizes a timeline of exposure, extending over 2 decades, for a bird species thought to be particularly vulnerable to oil contamination in marine environments. Environ Toxicol Chem 2017;36:1294–1300. Published 2016 Wiley Periodicals Inc. on behalf of SETAC. This article is a US government work and, as such, is in the public domain in the United States of America.
Visualizing dispersion interactions through the use of local orbital spaces
Authors: Wuttke Axel , Mata Ricardo A.
Published: October 2016

The interpretation of chemical properties/phenomena can often be aided through the use of imagery. The mapping of molecular electrostatic potentials is a prime example, serving as a guideline in the design of novel compounds or understanding transition state stabilization effects. It is today a common tool for theoreticians and experimentalists alike. With the emergence of concepts such as dispersion energy donors, and the overall importance of dispersion in chemical systems, representations targeting such a class of interactions are warranted. In this work, we make use of local orbital analysis to extract dispersion interactions and represent them in a scalar quantity, the Dispersion Interaction Density (DID). A particular advantage of the method is the possibility to represent at the same footing intermolecular and intramolecular interactions in a straightforward fashion from wave function calculations. We present examples for the benzene dimer, several substituted benzenes and a coupled diamondoid molecule. © 2016 Wiley Periodicals, Inc.
Dermal‐Epidermal Cross‐Talk: Differential Interactions With Microvascular Endothelial Cells
Authors: Bassino Eleonora , Vallariello Edoardo , Gasparri Franco , Munaron Luca
Published: October 2016

The biological importance of circulatory blood supply and angiogenesis for hair growth is now well recognized, but the their regulatory mechanisms require more mechanistic investigation. In vitro cocultures and tricultures can be successfully employed to greatly improve our knowledge on paracrine crosstalk between cell types that populate the dermal‐epidermal interface and cutaneous vasculature. Here we report that human dermal fibroblasts (NHDF) promote viability and proliferation of microvascular endothelial cells (HMVEC), while HMVEC are not mitogenic for NHDF. In triculture setup, conditioned media (CM) obtained by cocultures (HMVEC/NHDF or HMVEC/follicle fibroblasts) differently modulate growth and proliferation of keratinocytes and alter the expression of metabolic and pro‐inflammatory markers. In conclusion, tricultures were successfully employed to characterize in vitro dermal‐epithelial and endothelial interactions and could integrate ex vivo and in vivo approaches by the use of high‐throughput and standardized protocols in controlled conditions. J. Cell. Physiol. 232: 897–903, 2017. © 2016 Wiley Periodicals, Inc.
Temperature extremes in the Argentina central region and their monthly relationship with the mean circulation and ENSO phases
Authors: Rusticucci Matilde , Barrucand Mariana , Collazo Soledad
Published: October 2016

The aim of this study is to analyse the interannual variability of monthly climatic indices of extreme daily temperature in the central‐north region of Argentina throughout a year and its relationship with the atmospheric circulation. The impact of El Niño‐Southern Oscillation (ENSO) over different temperature indices throughout the year is specially analysed. Globally used indices in the 1970–2010 period are utilized for this purpose. The trends of temperature extremes show warming conditions in several months, especially in October and November. In order to find possible forcings of extreme temperature in the region at monthly scale, the co‐variability with other circulation monthly time series such as changes in the intensity of Southern Hemisphere semi‐permanent anticyclones and the intensity of the subtropical jet were studied. The main finding was a systematic shift of the South Atlantic anticyclone towards the west over the decades in June and August, which might hinder the cold advections over the region surveyed. Moreover, the influence of the variation on the intensity of the subtropical jet over extreme events showed significant positive (negative) correlations between the intensity of the jet and the frequency of cold (warm) indices in a great number of months. Finally, the influence of the ENSO phases on each of the temperature extremes analysed was studied. It was found that under El Niño conditions, minimum temperatures are affected quite evenly throughout the year, fostering the occurrence of warm nights. The impact of the El Niño event on the maximum extreme temperatures, however, shows seasonal differences. Between July and September warm days conditions are fostered, while between November and February the opposite (cold days) can be seen. This results in a decrease in the temperature range in the region surveyed during the summer months under El Niño conditions.
Cultural Effects on English Language Teachers’ Judgments of Metaphoric Creativity: A Mixed‐Methods Approach
Authors: Wang Hung‐Chun , Cheng Yuh‐Show , Chen Po‐Hsi , Su Shao‐Zu
Published: October 2016

This study explored cultural influences on English language teachers’ judgments of English metaphors created by Taiwanese learners of English. Based on a mixed‐methods approach, it delved into the rating severity and implicit evaluation criteria of two cultural groups of teachers: Taiwanese and Americans. Ten Taiwanese teachers and 10 American teachers evaluated 120 novel metaphoric expressions using the Consensual Assessment Technique (Amabile, 1996).Creativity in context: Update to the social psychology of creativity. They further filled out a creativity evaluation survey, which was designed to bring to light what qualities within the metaphors influenced their judgments of metaphoric creativity. With the teachers’ ratings being analyzed by means of many‐facet Rasch measurement, this study first indicated that the American teachers were more severe raters than the Taiwanese teachers, but no significant difference was found between them. Analysis of the evaluation survey further demonstrated that both cultural groups shared largely similar evaluation criteria; yet, two contrasts emerged between them. Specifically, the American teachers seemed to favor metaphors that expressed the creator's thoughts; by contrast, the Taiwanese teachers preferred metaphors that relied on readers’ imagination to work out the meanings. These findings shed light on implications for teaching creativity in English L2 classrooms and assessing learners’ creative language artifacts in an English L2 context.