bluuebunny/crossref_metadata_2025 huggingface dataset:
The Safety of Ethnic Foods in Campania Region: A Preliminary Study
Authors: Biondi Loredana , Fulgione Andrea , De Lella Assunta , Cutarelli Anna , Nappa Morena , Garofalo Francesca , Cavallo Stefania , Nava Donatella
Published: March 2023

Ethnic food is produced by an ethnic group—using their familiarity with local ingredients of plants and/or animal origin—and it is consumed in a country other than the country of origin. In Italy, the ethnic food market has expanded over the last three decades. The aim of this study was to evaluate the correct labeling, the microbiological communities and the allergens present in 50 ethnic foods. The visual inspection of labels and microbiological and allergen analyses have been carried out for evaluating their food safety. The visual inspection of labels revealed the absence of labeling in Italian and/or a failure to specify the place of origin. Microbiological analyses showed the absence of pathogens (i.e., Salmonella spp., Listeria monocytogenes and E. coli 0157:H7) in all matrices, but the presence of process hygiene indicator bacteria (total bacterial count, Coagulase-positive Staphylococci, Bacillus cereus, coliforms, yeasts and molds) was found in 37 samples. With regard to allergens, 12 samples were non-compliant for the presence of at least one allergen, while only two products were of species different from those declared on the label. This research highlights the need to increase the control of ethnic foods and also to improve the labeling system by standardizing international regulations.
The Anti-Fatigue Effect of Glycoprotein from Hairtail Fish (Trichiurus lepturus) on BALB/c Mice
Authors: Lu Xiaodan , Chen Jiaqi , Huang Luyao , Ou Yujia , Wu Jingru , Guo Zebin , Zheng Baodong
Published: March 2023

Fatigue is related to a variety of chronic diseases and has become a hot research topic in recent years. Various bioactive components have been extracted from hairtail fish (Trichiurus lepturus); however, none of these studies involved the anti-fatigue activity of hairtail fish glycoprotein (HGP). Thus, antioxidant experiments were conducted in vitro, and the anti-fatigue activity of HGP was further evaluated in BALB/c mice. The effects of HGP on the behavior of BALB/c mice were verified by classical behavioral experiments, and the indicators related to anti-fatigue activity were detected. The results showed that the antioxidant capacity in vitro of HGP increased gradually in the concentration range of 10 to 100 mg/mL. HGP improved the exercise ability of the mice. HGP was also found to significantly (p < 0.05) reduce the serum levels of lactate dehydrogenase (LDH), blood lactic acid (BLA), blood urea nitrogen (BUN), and creatine kinase (CK). The contents of liver glycogen (LG) and muscle glycogen (MG) were also significantly (p < 0.05) increased by HGP. Malondialdehyde (MDA) content in the serum and brains of the mice was significantly (p < 0.05) reduced and catalase (CAT), glutathione peroxidase (GPX), and superoxide dismutase (SOD) were significantly (p < 0.05) increased by HGP, especially in the middle- and high-dose groups. These results enhance our understanding of the anti-fatigue function of HGP and lay an important foundation for the further development and utilization of hairtail fish resources.
Extended Convergence of Two Multi-Step Iterative Methods
Authors: Regmi Samundra , Argyros Ioannis K. , John Jinny Ann , Jayaraman Jayakumar
Published: March 2023

Iterative methods which have high convergence order are crucial in computational mathematics since the iterates produce sequences converging to the root of a non-linear equation. A plethora of applications in chemistry and physics require the solution of non-linear equations in abstract spaces iteratively. The derivation of the order of the iterative methods requires expansions using Taylor series formula and higher-order derivatives not present in the method. Thus, these results cannot prove the convergence of the iterative method in these cases when such higher-order derivatives are non-existent. However, these methods may still converge. Our motivation originates from the need to handle these problems. No error estimates are given that are controlled by constants. The process introduced in this paper discusses both the local and the semi-local convergence analysis of two step fifth and multi-step 5+3r order iterative methods obtained using only information from the operators on these methods. Finally, the novelty of our process relates to the fact that the convergence conditions depend only on the functions and operators which are present in the methods. Thus, the applicability is extended to these methods. Numerical applications complement the theory.
On Discrete Weighted Lorentz Spaces and Equivalent Relations between Discrete ℓp-Classes
Authors: Agarwal Ravi P. , Rabie Safi S. , Saker Samir H.
Published: March 2023

In this paper, we study some relations between different weights in the classes Bp,Bp*,Mp and Mp* that characterize the boundedness of the Hardy operator and the adjoint Hardy operator. We also prove that these classes generate the same weighted Lorentz space Λp. These results will be proven by using the properties of classes Bp,Bp*,Mp and Mp*, including the self-improving properties and also the properties of the generalized Hardy operator Hp, the adjoint operator Sq and some fundamental relations between them connecting their composition to their sum.
Polymorphisms and mRNA Expression Levels of IGF-1, FGF5, and KAP 1.4 in Tibetan Cashmere Goats
Authors: Song Tianzeng , Tan Yao , Cuomu Renqing , Liu Yacheng , Ba Gui , Suo Langda , Wu Yujiang , Cao Xiaohan , Zeng Xianyin
Published: March 2023

The Tibetan cashmere goat is a precious breed in China and its cashmere is widely used in clothing and textiles. The genes IGF-1, FGF5, and KAP 1.4 have been shown to be crucial regulators of cashmere growth. In this study, we examined mRNA expression levels of these three genes and detected IGF-1, FGF5, and KAP 1.4 SNP loci in the Tibetan cashmere goat. After amplification and sequence alignment of the genes IGF-1, FGF5, and KAP 1.4 among 206 Tibetan cashmere goats, two new SNP loci were detected in gene KAP 1.4, while no SNP loci were found in amplified fragments of genes IGF-1 and FGF5. The expression levels of gene IGF-1 in Baingoin and Nyima counties were significantly higher than in other counties (p < 0.05). Moreover, the expression level of gene FGF5 in Gêrzê was significantly higher than in Rutog. The expression levels of mRNA in KAP 1.4 showed significant variation among seven counties. There were no significant differences in mRNA expression levels of IGF-1, FGF5, and KAP 1.4 in Tibetan cashmere goats when analysed by sex. The gene IGF-1 was slightly up-regulated in one to five-year-old cashmere goats, except in those that were 4 years old. The mRNA expression levels of FGF5 in one and two-year-old cashmere goats was lower compared with those in three to five-year-old cashmere goats. KAP 1.4 was up-regulated across one to five-year-old cashmere goats. In this study, SNP detection and mRNA expression analysis of IGF-1, FGF5, and KAP 1.4 genes was able to add data to genetic evolutionary analysis. Further studies should be carried out in SNPs to detect other fragments in genes IGF-1 and FGF5, as well as signal pathways and gene functions in protein levels of genes IGF-1, FGF5, and KAP 1.4 in the Tibetan cashmere goat.
Investigation of the Geological Structure of the Tramutola Area (Agri Valley): Inferences for the Presence of Geofluids at Shallow Crustal Levels
Authors: Olita Fabio , Giampaolo Valeria , Rizzo Enzo , Palladino Giuseppe , Capozzoli Luigi , De Martino Gregory , Prosser Giacomo
Published: March 2023

The Tramutola area in the High Agri Valley represents a key for the Southern Apennines fold and thrust belt. There, natural oil seeps from small carbonate reservoirs located at shallow depths that have been historically known since the 19th century, and hypothermal water was discovered during hydrocarbon exploration. From a geological point of view, the study area, extending for about 11 km2, is characterized with the presence of a complete section of the tectonic units of the southern Apennines and a complex structural framework that has not yet been fully clarified. In this work, geological analysis is based on new lithological and structural data, acquired during a detailed geological survey, compared with well logs obtained during exploration for hydrocarbons. Furthermore, a new geophysical investigation down to a 1 km depth (deep electrical resistivity tomography) allowed inference of buried structural and geological characteristics of the studied area. Through combining surface and subsurface data, some preliminary considerations about the structural setting and geofluid presence down to a 1 km depth have been made. Furthermore, geological–structural cross-sections have been constructed with the purpose of depicting the geometries of structures affecting the Apennine nappe pile in the subsurface, possibly favoring early uprising of hydrocarbons as well as circulation of hypothermal fluids and associated gases rising from deeper reservoirs.
From Global Studies to Global Humanities
Authors: Amirell Stefan
Published: March 2023

In contrast to the field of global studies, which has seen spectacular expansion and institutionalisation since the turn of the twenty-first century, there have to date been only a few attempts to promote or institutionalise global humanities as a field of study or research. Moreover, even though several disciplines in the humanities have undergone global turns in recent years, the humanities, with the exception of a certain brand of global history, are not prominent within the field of global studies. Against this background, this article surveys the various attempts that have been made in recent years to promote the concept of global humanities in the form of international scholarly networks, departments, and study programs, and the handful of attempts to sketch the outlines of a research agenda for global humanities. The strengths and limitations of the current approaches are discussed, and the articles advocating the notion of global humanities as a field or framework of research are brought into conversation with one another. Some common themes are identified in the literature on global humanities to date, such as the ambition for the field to be globally inclusive, critical, and transdisciplinary. Building on the recent global turns in some of the humanities disciplines and the steps that have been taken to purge these of traditional national and Eurocentric biases, global humanities should aim to develop frameworks of analysis that can be used to study all cultural expressions of humankind and to foster intercultural dialogue and understanding. Such an undertaking goes beyond the study of modern globalisation, which is the subject matter of global studies.
A Survey on Scabies Inpatients in South Korea Based on Health Insurance Claims Data from 2010 to 2019
Authors: Kim Hyung-Seon , Bang Jji-Ya , Cha Kyung-Sook
Published: March 2023

Due to the growing aging population and the increased number of long-term patients staying in nursing facilities, the prevalence of scabies has recently been increasing, even in developed countries. This study aimed to identify the actual status of hospitalized patients with scabies in South Korea using the national health insurance claims data. From 2010 to 2019, 2586 patients were hospitalized with scabies (B86) as the primary diagnosis. There were more females than males (χ2 = 31.960, p < 0.001) and patients aged 80 years or older in long-term care hospitals (χ2 = 431.410, p < 0.001). Scabies patients were mainly hospitalized in internal medicine, family medicine, and dermatology for all provider types (χ2 = 170.033, p < 0.001). In long-term care hospitals, the rate of accompanying dementia was 31.9% (χ2 = 193.418, p < 0.001), cerebral infarction was 10.4% (χ2 = 106.271, p < 0.001), and cancer was 2.1% (χ2 = 17.963, p < 0.001), which was higher than other provider types. Additionally, 20.6% in general hospitals (χ2 = 198.952, p < 0.001) had an indwelling catheter, while 49.1% in hospitals and 41.1% in general hospitals were administered steroids (χ2 = 214.440, p < 0.001). The KOH smear test was performed in 11.3% of all inpatients with scabies. We suggest recognizing these characteristics of scabies patients and thoroughly checking the skin lesions during physical examination for early diagnosis and prevention of scabies infection.
Development and Testing of the Smart Healthcare Prototype System through COVID-19 Patient Innovation
Authors: Chiu Po-Chih , Su Kuo-Wei , Wang Chao-Hung , Ruan Cong-Wen , Shiao Zong-Peng , Tsao Chien-Han , Huang Hsin-Hsin
Published: March 2023

Since the outbreak of the novel coronavirus disease 2019 (COVID-19), the epidemic has gradually slowed down in various countries and people’s lives have gradually returned to normal. To monitor the spread of the epidemic, studies discussing the design of related healthcare information systems have been increasing recently. However, these studies might not consider the aspect of user-centric design when developing healthcare information systems. This study examined these innovative technology applications and rapidly built prototype systems for smart healthcare through a systematic literature review and a study of patient innovation. The design guidelines for the Smart Healthcare System (SHS) were then compiled through an expert review process. This will provide a reference for future research and similar healthcare information system development.
Validity and Reliability of a Questionnaire on the Knowledge, Attitudes, Perceptions and Practices toward Food Poisoning among Malaysian Secondary School Students: A Pilot Study
Authors: Ramu Pawitra , Osman Malina , Abdul Mutalib Noor Azira , Aljaberi Musheer A. , Lee Kuo-Hsin , Lin Chung-Ying , Hamat Rukman Awang
Published: March 2023

Children in school settings are at risk of contracting food poisoning due to inadequate food safety practices and safe eating behaviors. This research aimed to develop a valid and reliable questionnaire on the knowledge, attitudes, perceptions, and practices (KAP2) toward food poisoning and its prevention among secondary school students. The questionnaire was developed by considering the Health Belief Model (HBM). A pilot study using a cross-sectional survey was conducted in Tangkak, Johor, among 30 selected students using a convenience sampling method. A pre-test was conducted on 15 secondary school students aged 13–17 years old prior to the pilot study, and they were excluded from the pilot study. The constructed knowledge was assessed using the difficulty and discrimination indices. Meanwhile, the reliability of the attitude, practice, and perception components in the questionnaire were assessed using Cronbach’s alpha. Regarding knowledge (34 items), the difficulty index showed that most items (n = 28) were easy, while one was difficult, and the remaining five were within an acceptable range. In addition, the discrimination index of the knowledge component (34 items) showed that twenty-two, three, and one had good, acceptable, and excellent ranges, respectively. Only eight items had a low discrimination power. All items of the attitude and practice components (10 items for each) showed a corrected item-total correlation value of >0.30. Only four out of twenty-one items of the perception component showed an unacceptable range of <0.30. However, following a discussion with the experts, all items were retained. With the incorporation of the HBM, the 75-item adapted food poisoning KAP2 questionnaire is valid and reliable. It can be utilized to measure and generate food poisoning KAP2 among secondary school students in Malaysia.
Factors Influencing the Use of Walking Aids by Frail Elderly People in Senior Day Care Centers
Authors: Sakano Yuya , Murata Shin , Goda Akio , Nakano Hideki
Published: March 2023

Background: Senior day care centers in Japan are the most commonly used insurance service for frail elderly people, and it is important to examine the factors that influence the use of walking aids at these centers. We aimed to investigate the factors affecting the use of walking aids by frail elderly patients in senior daycare centers. Methods: A total of 131 frail elderly people (mean age 82.7 ± 6.4 years) formed our study population. They were divided into two groups: solo walking (n = 87) and walking aid (n = 44). Individuals with cognitive decline were excluded. All participants were assessed using Functional Independence Measure Motor (FIM-M) sub-scores. Grip strength, knee extension strength, the 10 s Chair Stand test for Frail elderly (Frail CS-10), Single Leg Standing (SLS), and Timed Up and Go (TUG) tests were measured and compared between the two groups. Results: The walking aid group scored significantly lower than the solo walking group for five items: FIM-M, knee extension muscle strength, Frail CS-10, SLS, and TUG (p < 0.05). Logistic regression analysis revealed that knee extension muscle strength was the only factor that affected the use or disuse of walking aids (p < 0.05). The cut-off value of the knee extensor muscle strength-to-weight ratio for walking alone was 28.5%. Conclusions: Knee extensor muscle strength was the most important factor in determining the use of a walking aid.
Reticulocyte Hemoglobin as a Screening Test for Iron Deficiency Anemia: A New Cut-Off
Authors: Aedh Abdullah I. , Khalil Mohamed S. M. , Abd-Elkader Alaa S. , El-Khawanky Mohamed M. , Alshehri Hamdan M. , Hussein Amr , Alghamdi Ali A. Lafi , Hasan Abdulkarim
Published: March 2023

Introduction: Latent iron deficiency (LID), in which iron stores in the body are depleted without incidental anemia, poses a key diagnostic challenge. Reticulocyte hemoglobin content (Ret-Hb) is directly correlated with the functionally available iron for heme synthesis in erythroblasts. Consequently, Ret-Hb has been proposed as an efficient iron status marker. Aim: To assess the importance of Ret-Hb in detecting latent iron deficiency as well as its use in screening for iron deficiency anemia. Materials and Methods: A study involving 108 individuals was conducted at Najran University Hospital, 64 of whom had iron deficiency anemia (IDA) and 44 of whom had normal hemoglobin levels. All patients were subjected to complete blood count (CBC), reticulocyte percentage, Ret-Hb, serum iron, total iron binding capacity (TIBC), and serum ferritin measurements. Results: A significant decrease in Ret-Hb level was observed in IDA patients compared to non-anemic individuals, with a cut-off value of 21.2 pg (a value below which indicates IDA). Conclusion: The measurement of Ret-Hb, in addition to CBC parameters and indices, provides an accessible predictive marker for both iron deficiency (ID) and IDA. Lowering the Ret-Hb cut-off could better allow for its use as a screening parameter for IDA.
Marble Architectural Elements and Liturgical Furniture of the Santa Giustina Basilica in Padova: New Archaeometric Data on the Importation of Proconnesian Marble in the Late Antique Adriatic
Authors: Vedovetto Paolo , Antonelli Fabrizio , Secco Michele , Artioli Gilberto
Published: March 2023

This paper examines eight marble samples from the architectural elements and liturgical furniture of the ecclesiastical complex of Santa Giustina in Padova (Italy), founded by the Rufus Venantius Opilio before AD 524. The provenance determination of the marbles was carried out by means of a multi-analytical approach combining mineralogical–petrographic investigations, performed by microscopic observations of thin sections, and the measurement of the ratios of stable carbon and oxygen isotopes. The results obtained were compared with up-to-date petrographic and isotopic databases (Antonelli and Lazzarini 2015), and they showed that the analyzed marbles come from the quarries of the island of Proconnesus in Asia Minor, modern Marmara Adası (Turkey). Archaeometric evidence, together with the stylistic and functional analysis of the pieces, suggests the direct importation of a complete set of sculptures, shipped at different stages of workmanship from the workshops of Constantinople and expressly ordered by a single patron, who can be identified as Opilio, founder of the basilica of Santa Giustina and praetorian prefect at the court of King Theodoric.
Identification and Expression Analysis of the bHLH Gene Family Members in Diospyros kaki
Authors: Han Weijuan , Zhang Qi , Suo Yujing , Li Huawei , Diao Songfeng , Sun Peng , Huang Lin , Fu Jianmin
Published: March 2023

Basic helix–loop–helix (bHLH) proteins belong to one of the largest families involved in plant growth, development, signal transduction, and secondary metabolism. Although bHLH genes have been previously identified in persimmon (Diospyros kaki), systematic studies have not been reported. A total of 59 bHLH family members have been identified from the “Xiaoguotianshi” persimmon transcriptome. These proteins were clustered into 12 groups from I to XII based on their phylogenetic relationships with Arabidopsis thaliana. Combined with the phylogenetic analysis, in silico expression patterns of five developmental stages, the protein–protein interaction analysis between DkbHLH and DkMYB proteins showed that the bHLH_Cluster-15548.1 protein sequence was identified to be highly similar to the AtGL3 (AT5G41315.1) protein, which is associated with flavonoid and proanthocyanidin (PA) biosynthesis. This study presents the systematic analysis of bHLH genes from D. kaki and provides valuable information for further research on the involvement of bHLH protein in anthocyanin biosynthesis.
Chemical Characterization, Antioxidant Activity, and Cytotoxity of Wild-Growing and In Vitro Cultivated Rindera umbellata (Waldst. and Kit.) Bunge
Authors: Todorović Slađana , Perić Marija , Nikolić Biljana , Mandić Boris , Cvetković Stefana , Bogdanović Milica , Živković Suzana
Published: March 2023

The aim of this study was to comparatively analyze chemical composition and biological activity of wild- and in vitro grown Rindera umbellata. Explants were cultivated on 0.003–0.3 M sucrose, fructose, or glucose. HPLC-DAD for quantifying rosmarinic (RA) and lithospermic B (LAB) acids and GC-MS/FID for qualitative pyrrolizidine alkaloids (PAs) detection were used. Antioxidant activity (DPPH and ABTS assays) and cytotoxicity (MTT test) were monitored. Identified PAs were 7-angeloyl heliotridane, lindelofine, 7-angeloyl heliotridine, 7-angeloyl-9-(+)-trachelanthylheliotridine, punctanecine, and heliosupine, with higher variability reported in wild-growing samples. Total phenolic contents (TPCs) were comparable in wild-growing and in vitro samples, but total flavonoid (TFC) and RA levels were multifold higher in in vitro samples. Notably, high concentration of LAB was detected in wild-growing roots. Amounts of 0.3 M and 0.1 M of sucrose were optimal for TFC and RA production, while maximal antioxidant activity was monitored in plants grown on 0.3 M sucrose. The MTT test indicated colorectal HT-29 as more sensitive than A549 lung adenocarcinoma and normal MRC-5 cells, showing selective sensitivity to wild-growing and 0.3 M sucrose samples. In conclusion, PAs in vitro, as well as TPC, TFC, RA, and LAB in both growing conditions were detected for the first time in R. umbellata.
The Construction of Volatile Profiles of Eight Popular Peach Cultivars Produced in Shanghai Using GC-MS and GC-IMS
Authors: Wang Xia , Li Xiongwei , Su Mingshen , Zhang Minghao , Hu Yang , Du Jihong , Zhou Huijuan , Zhang Xianan , Ye Zhengwen , Yang Xuelian
Published: March 2023

Peach (Prunus persica L.) is an economically important fruit crop worldwide due to its pleasant flavor. Volatile organic compounds (VOCs) are vital factors for assessing fruit quality. Here, we constructed the VOC profiles for the top eight popular commercial peach cultivars produced in Shanghai by combining gas chromatography-mass spectrometry (GC-MS), odor activity value and gas chromatograph-ion mobility spectrometry (GC-IMS). Seventy VOCs were detected using GC-MS, of which twenty-three were commonly found in eight peach cultivars, including hexanal, nonanal, benzaldehyde, 2-hexenal, butyl acetate, hexyl acetate, (Z)-3-hexen-1-yl acetate, linalool, β-myrcene, D-limonene, 1-hexanol, 3-hexenol, 2-hexenol, 2-ethyl-1-hexanol, γ-octalactone, δ-decalactone, γ-hexalactone, γ-decalactone, γ-dodecalactone, β-ionone, 2-octanone, 2-ethyl furan and 2,4-ditert-butyl phenol. A total of 17 VOCs were screened on the basis of OAV ≥ 1 and the top 5 of this contribution were γ-decalactone, β-ionone, hexanal, 2-hexenal and linalool. Lactones had the highest OAV in HJML and terpenoids had the highest OAV in JC. JXIU had the lowest OAV of lactones and terpenoids. Based on the range of their OAV values, the flavor evaluation standard of Shanghai high-quality peach cultivars can be established, which is also a reference for breeding excellent offspring. Twenty-six VOCs were detected using GC-IMS, and the largest proportion were aldehydes. Principal component analysis (PCA) showed that Hikawa Hakuho (HH) and Jinchun (JC) were distant from the other samples, indicating that their volatiles were more distinct. These results provide a foundation for improving our understanding of aroma compositions in these high-quality peach cultivars, which might also provide a reference for future design breeding to improve fruit flavor.
A Multimethodological Approach for the Valorization of “Senatore Cappelli” Wheat Milling By-Products as a Source of Bioactive Compounds and Nutraceutical Activity
Authors: Vinci Giuliana , Prencipe Sabrina Antonia , Armeli Federica , Businaro Rita
Published: March 2023

Wheat is the third most cultivated cereal in the world and represents the major contributor to human nutrition. Milling wheat by-products such as husks (17–20% of the total processing output weight), even if still containing high-value-added bioactive compounds, are often left untreated or unused, thus resulting in environmental and human health burdens. In these regards, the present study is aimed at evaluating in a multimethodological approach the nutraceutical properties of durum wheat husks belonging to the ancient cultivar “Senatore Cappelli”, thus assessing their potential as bioactive compound sources in terms of phytochemical, cytotoxic, and nutraceutical properties. By means of HPLC-FD analyses, wheat husk samples analyzed revealed a higher content of serotonin, amounting to 35% of the total BAs, and were confirmed to occur at biogenic amines quality index (BAQI) values <10 mg/100 g. In addition, spectrophotometric assays showed a significant variable content in the phenolic (189.71–351.14 mg GAE/100 g) and antioxidant compounds (31.23–37.84 mg TE/100 g) within the wheat husk samples analyzed, according to the different cultivar areas of origin. Considering wheat husk extracts’ anti-inflammatory and antioxidant activity, in vitro analyses were performed on BV-2 murine microglia cells cultured in the presence or absence of LPS, thus evaluating their ability to promote microglia polarization towards an anti-inflammatory phenotype. Cytotoxicity assays showed that wheat extracts do not affect microglia viability. Wheat husks activity on microglial polarization was assessed by analyzing the expression of M1 and M2 markers’ mRNA by RT-PCR. Wheat husk antioxidant activity was assessed by analysis of NRF2 and SOD1 mRNA expression. Moreover, the sustainability assessment for the recovery of bioactive components from wheat by-products was carried out by applying the life cycle assessment (LCA) methodology using SimaPro v9.2.2. software.
Do Individuals with High Climate Anxiety Believe That They Will Die Earlier? First Evidence from Germany
Authors: Hajek André , König Hans-Helmut
Published: March 2023

Objectives: To examine the association between climate anxiety and perceived longevity in the general adult German population (also stratified by age group). Study design: Nationally representative survey. Methods: Data were used of the general adult German population, with n = 3015 individuals (18 to 74 years; data collection: March 2022). Climate anxiety was assessed using the validated Climate Anxiety Scale. It was adjusted for a wide array of covariates in linear-log regression analysis. Results: Even after adjusting for various covariates, there was an association between higher (log) climate anxiety and a lower perceived longevity in the total sample (β = −1.41, p < 0.01). Stratified by age group, a significant association was only present among individuals aged 18 to 29 years (β = −3.58, p = 0.01), whereas it was not present in the other age groups (i.e., individuals aged 30 to 49 years, individuals aged 50 to 64 years, and individuals aged 65 years and over). Conclusions: This study showed an association between higher climate anxiety and lower perceived longevity, particularly among younger individuals. More clearly, younger individuals with a higher climate anxiety think they will die earlier. This is the first study on this topic and could serve as a foundation for upcoming research. For example, longitudinal studies are needed to confirm our findings.
Digital Eye Strain among Peruvian Nursing Students: Prevalence and Associated Factors
Authors: Huyhua-Gutierrez Sonia Celedonia , Zeladita-Huaman Jhon Alex , Díaz-Manchay Rosa Jeuna , Dominguez-Palacios Albila Beatriz , Zegarra-Chapoñan Roberto , Rivas-Souza María Angélica , Tejada-Muñoz Sonia
Published: March 2023

There has been a high prevalence of digital eye strain (DES) among students who have received distance-learning lessons due to COVID-19. However, in low- and middle-income countries, there are few studies that have analyzed its associated factors. This study aimed to determine the prevalence of DES and its associated factors among nursing students during COVID-19 distance learning. This was a cross-sectional analytical study conducted between May and June 2021 in six Peruvian universities. The sample comprised 796 nursing students. DES was measured using the Computer Vision Syndrome Questionnaire (CVS-Q). A bivariate logistic regression analysis was performed. DES was found in 87.6% of nursing students. Sitting upright (OR, 0.47; 95% IC, 0.30–0.74), using electronic devices for more than four hours a day (OR, 1.73; 95% IC, 1.02–2.86), not following the 20-20-20 rule (OR, 2.60; 95% IC, 1.25–5.20), having the screen brightness very high (OR, 3.36; 95% IC, 1.23–11.8), and not wearing glasses (OR, 0.59; 95% IC, 0.37–0.93) are factors associated with DES. The prevalence of DES among nursing students is high. Improving the ergonomics of study environments, reducing the time of exposure to electronic devices, adjusting the screen brightness, and taking eye-care measures are key to controlling computer vision syndrome in virtual learning.
Triage Algorithms for Mass-Casualty Bioterrorism: A Systematic Review
Authors: Zhao Feida , Zhao Chao , Bai Song , Yao Lulu , Zhang Yongzhong
Published: March 2023

Objectives: To understand existing triage algorithms, propose improvement measures through comparison to better deal with mass-casualty incidents caused by bioterrorism. Study Design: Systematic review. Methods: Medline, Scopus and Web of Science were searched up to January 2022. The studies investigating triage algorithms for mass-casualty bioterrorism. Quality assessment was performed using the International Narrative Systematic Assessment tool. Data extractions were performed by four reviewers. Results: Of the 475 titles identified in the search, 10 studies were included. There were four studies on triage algorithms for most bioterrorism events, four studies on triage algorithms for anthrax and two studies on triage algorithms for mental or psychosocial problems caused by bioterrorism events. We introduced and compared 10 triage algorithms used for different bioterrorism situations. Conclusion: For triage algorithms for most bioterrorism events, it is necessary to determine the time and place of the attack as soon as possible, control the number of exposed and potentially exposed people, prevent infection and determine the type of biological agents used. Research on the effects of decontamination on bioterrorism attacks needs to continue. For anthrax triage, future research should improve the distinction between inhalational anthrax symptoms and common disease symptoms and improve the efficiency of triage measures. More attention should be paid to triage algorithms for mental or psychosocial problems caused by bioterrorism events.
Government as a Facilitator versus Inhibitor of Social Entrepreneurship in Times of Public Health Emergencies
Authors: Kamran Shah Muhammad , Nassani Abdelmohsen A. , Abro Muhammad Moinuddin Qazi , Khaskhely Mahvish Kanwal , Haffar Mohamed
Published: March 2023

COVID-19 established the need for even more social entrepreneurship globally. It is important for keeping society together in times of crises because it creates an environment that improves the quality of life during hard times and public health emergencies such as COVID-19. Even though it plays a unique role in returning things back to normal after a crisis, it faces opposition from many parts of society, especially the government. Still, there are not many studies that look at what the government should do to help or stop social enterprise during public health emergencies. That is why the goal of this study was to find out how the government has helped or hindered social entrepreneurs. Content analysis was conducted on the carefully mined data from the internet. The research found that regulations for social enterprises should be loosened, especially during and after pandemics and disasters. This could also make it easier to accomplish things in the government. It was also found that, in addition to financial help, capacity building through training can help social enterprises do more and make a bigger difference. This research provides broader guidelines for policymakers and new entrants in the field.
Developing Medication Review Competency in Undergraduate Pharmacy Training: A Self-Assessment by Third-Year Students
Authors: Westerholm Aleksi , Leiman Katja , Kiiski Annika , Pohjanoksa-Mäntylä Marika , Mistry Anita , Airaksinen Marja
Published: March 2023

Pharmacists are increasingly involved in medication history taking, medication reconciliation, and review in their daily practice. The objectives of this study were to investigate third-year pharmacy students’ self-assessed competency in medication reviews and gather their feedback for further development of medication review training in their curriculum. The study was conducted as a self-assessment of third-year pharmacy students at the completion of their second three-month internship period in a community pharmacy in 2017–2018. The students were assigned to review medications of a real patient under the supervision of a medication review accredited pharmacist during their internship. The self-assessment was carried out via an e-form, which was created for this study. Recently established national medication review competence recommendations for pharmacists were used as a reference. Students (n = 95, participation rate: 93%) self-assessed their competency as good or very good in 91% (n = 28) of the competency areas listed in the self-assessment. The highest proportion of competencies that were self-assessed as good or very good included using medication risk management databases and evaluating the clinical importance of the information (97%, n = 92). The lowest proportion of competencies was found in applying clinical information from the key laboratory tests to patient care and knowing which laboratory tests are most important to monitor in each condition and medication (36%, n = 34). The students suggested that their pharmacy education should contain more medication review assignments as group work and that an elective course on medication reviews should be compulsory for all pharmacy students.
Drop Jump Performance Improves One Year Following Anterior Cruciate Ligament Reconstruction in Sportsmen Irrespectively of Psychological Patient Reported Outcomes
Authors: Legnani Claudio , Del Re Matteo , Peretti Giuseppe M. , Macchi Vittorio , Borgo Enrico , Ventura Alberto
Published: March 2023

Our study aims to prospectively report the functional outcomes of 31 sportsmen following anterior cruciate ligament (ACL) reconstruction, up to 12 months after surgery, with regards to subjective tests and drop jump performance, and to investigate the correlations between these variables, to be used for determining the return to sports after ACL reconstruction. Lysholm score, Tegner activity level, and the ACL–Return to Sport after Injury (ACL-RSI) scale were evaluated preoperatively, at 6 months, and at 12 months after surgery. Drop vertical jump was recorded using an infrared optical acquisition system. Lysholm and ACL-RSI scores significantly improved at the 12-month follow-up compared to the baseline and 6-month evaluations (p < 0.001). Concerning Tegner activity level, no statistically significant differences were reported between pre- and post-operative status (p = 0.179). Drop jump limb symmetry index significantly improved at 12 months, with the mean value improving from 76.6% (SD: 32,4) pre-operatively to 90.2% (SD: 14.7; p < 0.001) at follow-up. Scarce positive correlation was reported between the ability to perform drop jumps and activity level in athletes one year after ACL reconstruction. In addition, subjective knee score and psychological readiness were not related to jumping performance.
The Effects of High-Altitude Mountaineering on Cognitive Function in Mountaineers: A Meta-Analysis
Authors: Li Lun , Zhou Yun , Zou Shisi , Wang Yongtai
Published: March 2023

Background: Nowadays, with the convenience of international traveling and driven by many individuals’ fond dreams of challenging high-altitude exercises, high-altitude mountaineering is becoming increasingly popular worldwide. Therefore, we performed a meta-analysis to determine the effects of high-altitude mountaineering on cognitive functions in mountaineers before and after climbing. Methods: After a thorough electronic literature search and selection, eight studies were included in this meta-analysis, and the conducted test cycles ranged from 8 to 140 days. Eight variables were included in this meta-analysis: the Trail-Making Test (TMB), Digit Span-Forward (DSF), Digit Span-Backward (DSB), Finger Tapping Test-Right (FTR) Finger Tapping Test-Left (FTL), Wechsler Memory Scale Visual (WMSV), the Aphasia Screening Test (Verbal Items) (AST-Ver), and the Aphasia Screening Test (Visual Motor Errors) (AST-Vis). The effect sizes (ES) and forest plots of these eight variables were generated. Results: Five variables (TMB, ES = 0.39; DSF, ES = 0.57; FTR, ES = 0.50; FTL, ES = 0.16; WMSV, ES = 0.63) out of eight were significantly improved after high-altitude mountaineering, whereas the ES values of DSB, AST-Ver, and AST-Vis did not show significant improvement after climbing. Conclusion: Despite two limitations, namely, methodological issues inherent in the meta-analysis and the inability to explain high heterogeneity between studies, this study is the first meta-analysis that has attempted to specify and compare the cognitive functions of mountaineers before and after high-altitude mountaineering. Furthermore, as a short-term plateau exercise, high-altitude mountaineering has no significant negative impacts on the cognitive functions of climbers. Future research is needed for a long period of high-altitude mountaineering.
Retinal Microvasculature and Neural Changes and Dietary Patterns in an Older Population in Southern Italy
Authors: Tatoli Rossella , Lampignano Luisa , Donghia Rossella , Niro Alfredo , Castellana Fabio , Bortone Ilaria , Zupo Roberta , Tirelli Sarah , Lozupone Madia , Panza Francesco , Alessio Giovanni , Boscia Francesco , Sborgia Giancarlo ,   on behalf of the Eye Clinic Research Group, Sardone Rodolfo
Published: March 2023

Background: Like other parts of the body, the retina and its neurovascular system are also affected by age-related changes. The rising age of populations worldwide makes it important to study the pathologies related to age and their potential risk factors, such as diet and eating habits. The aim of this study was to investigate the predictive power of food groups versus retinal features among noninstitutionalized older adults from Southern Italy using a machine learning approach. Methods: We recruited 530 subjects, with a mean age of 74 years, who were drawn from the large population of the Salus in Apulia Study. In the present cross-sectional study, eating habits were assessed with a validated food frequency questionnaire. For the visual assessment, a complete ophthalmic examination and optical coherence tomography-angiography analyses were performed. Results: The analyses identified 13 out of the 28 food groups as predictors of all our retinal variables: grains, legumes, olives-vegetable oil, fruiting vegetables, other vegetables, fruits, sweets, fish, dairy, low-fat dairy, red meat, white meat, and processed meat. Conclusions: Eating habits and food consumption may be important risk factors for age-related retinal changes. A diet that provides the optimal intake of specific nutrients with antioxidant and anti-inflammatory powers, including carotenoids and omega-3 fatty acids, could have beneficial effects.
Greening China’s Growth: Assessing the Synergistic Impact of Financial Development and Technological Innovation on Environmental Pollution Reduction—A Spatial STIRPAT Analysis
Authors: Peng Jiachao , Fu Shuke , Gao Da , Tian Jiali
Published: March 2023

To achieve sustainable economic development in China, it is crucial to balance economic growth and environmental protection. Financial capital and technology can contribute positively to environmental pollution control. This study employs the Cournot model to examine the impact of financial development and technological innovation on environmental pollution at the micro level. It utilizes the spatial STIRPAT model to analyze inter-provincial panel data from China between 2005 and 2020. The results show that China’s ecological environment pollution exhibits significant spatial dependence, and heavily polluted areas tend to agglomerate. While improving financial development can increase regional environmental pressure, positive spatial spillover improves environmental quality in neighboring areas. Conversely, technological innovation reduces local ecological pressure, with negative spatial spillover effectively curbing environmental pollution in surrounding regions. The results support the environmental Kuznets curve (EKC) hypothesis, which posits an inverted U-shaped relationship between economic growth and environmental pressure, while population growth increases environmental pressure. The findings are robust and have important policy implications.
Remote Sensing-Based Yield Estimation of Winter Wheat Using Vegetation and Soil Indices in Jalilabad, Azerbaijan
Authors: Karimli Nilufar , Selbesoğlu Mahmut Oğuz
Published: March 2023

Concerns about the expanding human population’s adequate supply of food draw attention to the field of Food Security. Future-focused analysis and processing of agricultural data not only improve planning capabilities in this field but also enables the required precautions to be taken beforehand. However, given the breadth and number of these regions, field research would be an expensive and time-consuming endeavour. With the advent of remote sensing and optical sensors, it is now possible to acquire diverse data remotely, quickly, and inexpensively. This study investigated the limitations and capabilities of remote sensing data application in the field of planning Food Security. As a result, Sentinel 2 and Shuttle Radar Topography Mission (SRTM) data were used to estimate winter wheat yields with a high degree of accuracy (98.03%) using the Mamatkulov technique and the MEDALUS model, which was both free and widely available. This method can make it possible to make predictions about the productivity of newly created crop fields or for which we do not have information about the productivity of previous years, without the need to wait for building regression models or any field studies. Considering the outcome, wide-range and larger analyses on this topic can be carried through.
Localization of False Data Injection Attack in Smart Grids Based on SSA-CNN
Authors: Shen Kelei , Yan Wenxu , Ni Hongyu , Chu Jie
Published: March 2023

In recent years, smart grids have integrated information and communication technologies into power networks, which brings new network security issues. Among the existing cyberattacks, the false data injection attack (FDIA) compromises state estimation in smart grids by injecting false data into the meter measurements, which adversely affects the smart grids. Current studies on FDIAs mainly focus on the detection of its existence, but there are few studies on its localization. Most attack localization methods have difficulty locating the specific bus or line that is under attack quickly and accurately, have high computational complexity and are difficult to apply to large power networks. Therefore, this paper proposes a localization method for FDIAs that is based on a convolutional neural network and optimized with a sparrow search algorithm (SSA–CNN). Based on the physical meaning of measurement vectors, the proposed method can precisely locate a specific bus or line with relatively low computational complexity. To address the difficulty of selecting hyperparameters in the CNN, which leads to the degradation of localization accuracy, a SSA is used to optimize the hyperparameters of the CNN so that the hyperparameters are optimal when using the model for localization. Finally, simulation experiments are conducted on IEEE14-bus and IEEE118-bus test systems, and the simulation results show that the method proposed in this paper has a high localization accuracy and can largely reduce the false-alarm rate.
Smart Machine Health Prediction Based on Machine Learning in Industry Environment
Authors: Yeruva Sagar , Gunuganti Jeshmitha , Kalva Sravani , Salkuti Surender Reddy , Kim Seong-Cheol
Published: March 2023

In an industrial setting, consistent production and machine maintenance might help any company become successful. Machine health checking is a method of observing the status of a machine to predict mechanical mileage and predict the machine’s disappointment. The most often utilized traditional approaches are reactive and preventive maintenance. These approaches are unreliable and wasteful in terms of time and resource utilization. The use of system health management in conjunction with a predictive maintenance strategy allows for the scheduling of maintenance times in such a way that device malfunction is avoided, and thus the repercussions are avoided. IoT can help monitor equipment health and provide the best outcomes, especially in an industrial setting. Internet of Things (IoT) and machine learning models are quite successful in providing ongoing knowledge and comprehensive study on infrastructure performance. Our suggested technique uses a mobile application that seeks to anticipate the machine’s health status using a classification method utilizing IoT and machine learning technologies, which might benefit the industry environment by alerting the appropriate maintenance team before inflicting significant harm to the system and disrupting normal operations. A comparison of decision tree, XGBoost, SVM, and KNN performance has been carried out. According to our findings, XGBoost achieves higher classification accuracy compared to the other algorithms. As a result, this model is selected for creating a user-based application that allows the user to easily check the state of the machine’s health.