bluuebunny/crossref_metadata_2025 huggingface dataset:
Colour Image Segmentation using Background Subtraction with Global and Local Threshold
Authors: Kaur Amanpreet
Published: June 2021

Image segmentation is one of the fundamental and essential steps in all the major applications of digital image processing. In this process the digital image is divided into various regions which are also known as segments. These segmented parts of the digital image could be used for further processing like detection of types of objects present in the segmented region, various tumors present in the digital images or the scene understanding process. Usually segmentation is classified as local segmentation and the global segmentation. Image segmentation is also classified on the basis of digital image properties also. In this case it is of two types. First one is non continuity detection and second one is the continuous detection. Various image segmentation techniques are proposed by researchers which have various limitations. Some techniques do not split the region uniformly and other techniques take enough time and memory for the processing of digital image. In this research work both the local and global thresholding concept is used to get the segmented regions of the image. The proposed technique will be able to extract the segmented objects from the digital image. To check the authenticity and efficiency of the proposed technique, it will be compared with other well known techniques of image segmentation using background subtraction of colored digital images. Time of computation, sensitivity and accuracy are used as objective parameters for the performance evaluation of the techniques. For the subjective evaluation visual quality of the digital image is used for performance evaluation.
Contention Mitigation based Level Shifter Architecture
Authors: Jakkannavar Shravan M
Published: June 2021

Energy efficiency is one of the most important issues that needs to be solved in the current system on chip design. To overcome this issue, many circuits inside the chip run at low power. However there are some blocks like memories that run at relatively higher voltages. This means, modern day SOC contains different voltages running through it. The problem arises when two blocks operating at different voltages want to communicate with each other. This problem is solved by using Level Shifters as an interfacer between the blocks. The function of Level Shifter is to convert voltage level of input signal to that of the output. In this paper a cross coupled architecture of Level Shifter is proposed which operates between 1.5v and 5v. The speciality of this architecture is there is less contention between pull up network and pull down network, which reduces the rise and fall delay significantly. The proposed design is simulated at different operating conditions and the functionality is checked.
Cone Shaped Multiband Antenna for Wireless Applications
Authors: Rajauria Vaishali
Published: June 2021

In this paper multi-band microstrip-fed monopole antenna is proposed to apply Satellite communication, GSM 860 & GSM 1800. A cone-shaped defected patch antenna with the reduced ground plane is proposed to build a multi-band antenna. Because of the defective patch, the antenna resonating in triple bands 860MHz, 1.8GHz &2. 1GHz.The size of the antenna is 72*1.6*100 mm3. The antenna simulation is done on CST software using FR-4 substrate.
Artificial Intelligence based BOT to Manage and Administer Cloud Services
Authors: Muzzamil P. Z
Published: June 2021

In the era of cloud computing, every company uses cloud technology for its applications and other infrastructure to provide a highly available and easily accessible user experience. While monitoring and managing these assets becomes a hectic work for the IT admins. On which the Level of Effort (LOE) of the resource allocated will be high and the resource must reach different console for different information. Introducing an AI-powered bot which can monitor and manage the cloud assets will reduce the manpower drastically. Most enterprises currently have very rudimentary systems of resource management where someone in the role of an Azure or resource administrator log on to the Admin Portal of their resources and have to apply filters and search through multiple screens to find even the most basic information regarding utilization and cost. This leads to inefficient management of resources and almost leads to overspending in resources that are being underutilized. The implementation of the project will involve creating a cloud services management bot that can be integrated with an enterprise’s collaboration suite as a way to enhance the enterprise’s modern workspace. The bot is to be trained on a set of query data as part of the artificial intelligence process using the natural language processing packages that are included in the Azure Cognitive Services suite. Once queries are processed, the system will connect with the respective endpoints of the Azure Resource Management REST APIs to retrieve relevant resource utilization information and show that to the end-user.
Health & Environmental Impact of Ultraviolet Radiation Exposure used in Currency Sanitizer
Authors: Mude Er. S. K.
Published: June 2021

Many of the ultraviolet (UV) sources used emit high intensities of UV light, capable of producing painful eye and skin burns. This paper provides information about the hazards associated with UV exposure and the safety precautions to take when working with these sources. Ultraviolet (UV) disinfection technology has existed for many years, but chemicals are still very prominent in disinfection applications today. UV disinfection does, however, provide many benefits over chemical options. It cannot be overdosed, and does not produce by-products, toxins, or volatile organic compound (VOC) emissions. It does not require the storage of hazardous materials and will not affect smell or taste in water and food disinfection applications. In addition, UV light is known to kill more waterborne microbes than chlorination. UV-C currency sanitizer is a fluid less device which can be used to perform the disinfection of various bacteria and viruses, it is based on UV-C light technology. It provides a portable ultraviolet disinfecting device for currency notes which comprises an acrylic case. The light is arranged in the top and bottom and inner layer coated with aluminum foil to increase the utilization of light rays.
Mixing Behavior and Pressure Drop Analysis of Micromixer with Different Geometric Conditions
Authors: Kadam Suraj S.
Published: June 2021

A 3-D design of and analysis of fluid flow in the micromixer with different configurations is carried out in this dissertation. The main purpose of this research is to obtain minimum mixing length as rapid mixing is essential in many of the micro-fluidic systems used in biochemistry analysis, drug delivery, sequencing, or synthesis of nucleic acids. Also effect on various parameters such as mixing behavior, volume arrow, mixing length, maximum velocity, maximum pressure, pressure drop, and velocity distribution were analyzed by changing the mixing angle between inlets. Micromixers with square cross-section rectangular mixing chamber with various types of obstacle place in fluid flow paths such as rectangular obstacles, elliptical obstacle, and circular obstacle in split and recombination manner were designed for the analysis. The micromixer has 3 inlets and 1 outlet. Water and ethanol were used as working fluids. For computational fluid dynamics analysis, COMSOL Multiphysics 5.0 is used. From various results, we have found that size, the geometry of mixing chambers and obstacles, and mixing angle effect mixing length, pressure, and velocity. With a decrease in mixing angle mixing length, pressure drop, and maximum velocity decrease i.e it gives better mixing performance. Also with an increase in the number of obstacles mixing length and maximum velocity decreases and pressure drop increases. Micromixer with mixing angle 60 degree and circular obstacles gives minimum mixing length than any other models consisting rectangular or elliptical obstacle and mixing angle greater than 60 degrees.
Alcohol Detection to Lock Engine and Incident Reporting
Authors: Navya Odde
Published: June 2021

Most of the road accidents are occurring due to drunk-driving. We hear about a lot of accidents these days that are caused by drunk driving. Drunk drivers are not in a stable state, and as a result, rash driving occurs on the roadways, endangering the lives of everyone on the road, including the driver. Thousands of traffic accidents were reported by the Indian Ministry of Statistics in 2016. Our project presents the design and implementation of “Alcohol Detection to Lock Engine and incident reporting” using alcohol sensor, arduino UNO, GSM Module. The system will continuously monitor level of alcohol concentration using MQ-3 alcohol sensor and thus turn off the engine of vehicle if the alcohol concentration is above threshold level. The LCD display is used to display the stat us of the vehicle. This model will send the message of whereabouts of the vehicle through GSM module thus reporting the incident .the project provides an efficient solution to control road accidents due to drunk driving.
Solar Tracking using Arduino
Authors: Singh Harshit
Published: June 2021

Solar energy is one of the most popular renewable energy sources. In this era, every country is trying to push its boundaries for more efficient renewal energy source. Every nation is concerned to minimize their carbon emission especially the develop countries like USA, Europe, Japan etc. Energy is everyone’s need and clean source of energy is important for no pollution. Solar trackers has been gaining popularity all around the world because of its maximizing efficiency of solar energy. Solar trackers have simple mechanism and easy to operate. It is able to track the sun in the sky for maximum sunlight throughout day. Sun is an ultimate source of energy to the earth and also a green source of energy. It is important and can wisely use to solve our energy crisis. Solar trackers can be best alternative to this. The power generated by panels can be used for domestic works and the rest can be transferred to the grid for energy distribution. The hardware of this project can be implemented by using few components like LDR (Light Dependent Resistor),motor, Arduino microcontroller and battery. .There are so still many villages that do not get any electricity supply. This project help to provide electricity in rural areas.
Lightweight Authentication Protocol for NFC based Anti-Counterfeiting System in IoT Infrastructure
Authors: N Dr. Rekha
Published: June 2021

Counterfeit medications are known as the medications that were manufactured for the purpose of deceptively representing as authentic, effective and original in the market. Such medications cause severe health issues for patients. Counterfeited drugs have an inimical effect on the human health. The legal manufacturing companies also face threats to their revenue loss due to these counterfeited medicines. In this paper, we introduce a novel authentication protocol for anti-counterfeited drugs systems based on Internet of Things (IoT) to help checking the validity of drugs ‘‘unit dosage’’. Our protocol uses the near-field communication (NFC) as it is convenient for mobile environment. The protocol also offers reliable update phase for NFC. Furthermore, our scheme is complemented with performance evaluation along with the use of random oracle model for formal security analysis.
Brain Tumor Detection with Deep Learning on MRI Image Dataset
Authors: Rakesh S.
Published: June 2021

Tumor is an unusual growth of the tissues in any part or organ of the human body. A brain tumor is an abnormal growth of cells in the brain or central spine canal. Brain tumors can be malignant (cancerous) or benign (non-cancerous) and have different treatments. Any extra growth of cells in the brain can result in pressure inside the skull as it is rigid and hence damages the brain. In the recent years, a progressive research has been done in this medical imaging field to more accurately detect the brain tumors. This is very important for early treatment. The proposed model detects the location and dimensions of the tumor present in the brain of a patient accurately using deep convolutional neural networks. In this paper we have presented the two models, Inception V3 and VGG-Net. The main aim of this paper is to find the best technique to detect the brain tumor from the MRI scanned images. The proposed models have given good results with good accuracy.
X-RAY-morphological features of the current COVID-19 and HIV infection
Authors: Gaus A. A. , Klimova N. V.
Published: June 2021

Infection of HIV-infected with a new coronavirus infection, due to its high contagiousness, is inevitably growing all over the world. According to estimates of Chinese scientists, their number is currently more than 500 thousand people. Considering that COVID-19 leads to suppression of immunity and the emergence of opportunistic infections in HIV-negative patients, the activation of secondary diseases in patients with HIV is natural. In view of this, the study of the features of the X-ray morphological picture of inflammatory changes in the lungs according to MSCT data in patients with COVID-19/HIV became the goal of this study. 13 patients who underwent treatment at the Surgut Regional Clinical Hospital during the period from March to July 2020 underwent MSCT of the chest organs upon admission, before discharge, as well as in case of deterioration or lack of effect from the therapy — every 3 days. The detection of pathognomonic CT signs of COVID-19 in the lungs in patients with HIV (the nature of the lesion, the stage of the disease, the severity of the inflammatory process) was carried out in parallel with the diagnosis of opportunistic infections. During the examination, atypical clinical and X-ray morphological signs of the course of COVID-19/HIV coinfection were identified. In HIV-infected people, COVID-19 proceeds more easily and in disguise, while opportunistic infections both in clinical and radiological manifestations have priority signs. They are the reasons for the aggravation of the course of the disease, as well as the development of complications in these patients.
Creation of integrated energy supply systems
Authors: Andreev Vyacheslav M. , Barinov Valentin A. , Varfolomeev Sergei D. , Lachuga Yurii F. , Matyukhin Vladimir F. , Panchenko Vladislav Ya. , Redko Ivan Ya. , Sigov Alexander S. , Stennikov Valery A.
Published: June 2021

A brief description of the State Electrification Plan of Russia (GOELRO plan), developed on the initiative of V.I. Lenin by the GOELRO commission headed by G.M. Krzhizhanovsky and adopted on December 22, 1920 by the 8th All-Russian Congress of Soviets, as well as key directions of a long-term plan for research on the problem of the creation of the Unified Power System of the Country (UPS), developed by the commission under the leadership of G.M. Krzhizhanovsky in 1957, which laid the foundation for the formation of the UPS - the largest in the world at the end of the 80s centrally managed interconnected power system, is presented. The indicators of development and efficiency of the country's electric power industry are given. The essential part of the reforms in the electric power industry of Russia carried out at the beginning of the 21st century, their shortcomings that led to a decrease in the efficiency of the industry and the emergence of various kinds of bottlenecks and imbalances are analyzed. The processes of transformation of energy systems in the world are considered, as a result of which a new architecture of energy systems is created. The primary tasks facing the Russian power industry in these conditions are formulated.
Multijunction solar arrays for space and terrestrial applications
Authors: Andreev Viacheslav M.
Published: June 2021

Photovoltaic conversion of the solar energy is the most prospective direction of the renewable power engineering. Solar arrays ensure power supply of spacecrafts and are gaining increasingly more application on the Earth. In the majority of developed countries, laws on state support of the green power engineering assisted in a substantial increase of power of the solar photovoltaic systems have been adopted. The main barrier to increasing the terrestrial solar photovoltaics development rates is a relatively high cost of the solar electric power. The ways for reducing the cost are the rise of the efficiency of power systems and the reduction of the material consumption for arrays based on multijunction solar cells. Results of multijunction solar cells and modules developments for space and terrestrial solar arrays are discussed in the article. In the last years, a significant experience on creation of multijunction solar cells was accumulated. Cascade solar cells and solar photovoltaic installations on their base with sunlight concentrators have been developed. At present, the terrestrial cascade solar cell efficiency exceeds 45%, which is substantially higher than that in conventional Si and thin-film solar arrays. The cascade solar cell efficiency increase has been achieved at the expense of splitting the sunlight spectrum into several intervals by the solar cell semiconductor structure fulfilling more effective photon energy conversion of each of these intervals in a definite parts of this structure. It is shown that multijunction solar cells provide the highest efficiency and they are the basic components of space arrays. Multijunction solar cells provide the highest conversion efficiency of concentrated sunlight as well. It opens prospects for decreasing the solar cell area and cost proportionally to the sunlight concentration. Developed concentrated photovoltaic installations are promising for wide applications in the high scale terrestrial solar photovoltaic energetics.
State Electrification Plan of Russia - an example of a systematic approach to the long-term development of the national electric power industry
Authors: Vorotnitsky Valery E.
Published: June 2021

A brief history of the State Electrification Plan of Russia (GOELRO plan) development, established in 1920, and its execution during 15 years is considered. It is shown that the basic statements of the GOELRO plan were developed and discussed in pre-revolutionary Russia, and actually it was a state plan for the development of the country's economy for a long-term period. The analysis of the main trends of development in the world and national electric power industries based on the use of new technologies and techniques for the production, transmission and distribution of electricity is also presented. A list of key systemic problems in the modern Russian electric power industry aroused as a result of its reform in the post-Soviet period is discussed. The conclusion about the need of more active state government participation in the industry management, in the creation of a new regulatory framework to improve the efficiency of the management was done based on the analysis of the mentioned problems. It is suggesting the developing of a new GOELRO plan, which has to take into account modern trends in the development of world energy, the achievements of the Fourth Industrial Revolution; the positive experience of many years in the functioning of the Unified Power System of Russia and the prospects for the economic development of its regions.
“Trivial Nonsense” of the Poor Heroes of Dostoevsky (Materials for “Dostoevsky’s Language Dictionary: Idioglossary”)
Authors: Chulkina Nina L.
Published: June 2021

The paper represents lingvo-cultural and semiotic description of the vocabulary, which introduces the everyday life of the poor characters of the F. Dostoevskys novels. In this case the procedure of the construction of text associative fields and the concept of idiogloss are used. Associative text fields are built, from one side, around the base concepts of daily activity - HOUSE/DWELLING; CLOTHING; FOOD; MONEY, DEBTS, LOAN; DISEASE, DEATH; WORK, BUSINESS; and idioglosses POVERTY; SHAME; FEAR; PRIDE, THE PINCHED PRIDE; GENTLENESS - on the other hand. These two measurements - semantic and pragmatic - make it possible to reconstruct on the texts of Dostoevsky the everyday world of poor characters, to reveal those specific idiosenses, which are concluded in the lexical items being investigated. Besides, the author hopes that such description can become additional material for the creation of the corresponding articles of the Dostoevskys Language Dictionary, which is making now in the V.V. Vinigradov Russian Language University (Russian Science Academy). At the V.V. Vinogradov Russian Language University University of Russian Science Academy in the sector of experimental lexicography under the guidance of Corresponding Member of the Russian Science Academy, Professor Y.N. Karaulov, work on creation of the F.M. Dostoevskys Language Dictionary has been conducted for many years. At the same time, collections of articles are published - The Word of Dostoevsky, viewed as a kind of extension of Dostoevskys Language Dictionary. The authors of the collection should implement the overall thrust of the research results as a guide - the solution of interpretational, hermeneutic tasks. Meanwhile it is also important to identify and describe the vocabulary that is significant for interpretation of Dostoevskys texts and idioglosses in particular, i.e. such lexical units that are important for understanding, for deciphering and interpreting of the meaning of his literary works, for characterizing his authors style (idiostyle), for recreating his picture of the world, his universal and national ideals .
Contemporary Philosophy of the East: Tradition and Innovations
Authors: Al-Janabi Maythem M. , Lukyanov Anatoly E.
Published: June 2021

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Bodily Contemplation: On the Question of the Truth of the Perception of Physical Objects in Chinese Landscape Painting
Authors: Wang Yiqun
Published: June 2021

This article analyzes the views of representatives of the scientific community on ancient Chinese landscape painting, emphasis is mainly placed on views that concern the spiritual qualities of landscape painting, as well as rethinking concepts that ignore the significance of sensual perception. Landscape painting is usually considered as a spiritual work of Taoism: landscape painting developed from Taoist thought, Taoist philosophy determined the identity of the artistic style and the inherent spirit of landscape painting. Moreover, some researchers even believe that bodily contemplation of landscape painting means setting the very original nature of mountains and waters, and the "knowledge of the truth" is a spiritual process that is more blocked by the human capacity for sensual perception. Some of the scientists completely deny the possibility and truth of sensual perception of physical objects in landscape painting. The author of this article believes that the spiritual component of landscape painting lurks precisely in the value of sensual perception, and bodily contemplation of mountains and waters is impossible without the participation of the body, clear confirmation of which we find in the ancient Chinese theory of arts. Ancient Chinese works of art traditionally had a close connection with sensual perception through bodily contemplation. This process is not simply about capturing object information, but when the subject takes an active part in the vision of the object, when the subject gives feedback to the object, and through acquiring the object its meaning is transmitted. Only through bodily contemplation, the individual can fully feel the artistic value of landscape painting, and Taoist philosophy thus gains a real existence in landscape painting, becoming a kind of emotional thinking.
Vidzemes muižniecības un luterāņu garīdzniecības vīzija par zemnieku kārtas izglītošanu pēc dzimtbūšanas atcelšanas
Authors:   Latvijas Nacionālā bibliotēka, Daukšte Vija
Published: June 2021

Raksts ir veltīts Latvijas skolu vēsturē maz pētītam aspektam – valdošās laicīgās un garīgās elites vīzijai par zemnieku kārtas izglītošanu pēc dzimtbūšanas atcelšanas Vidzemē 1819. gadā. Rakstā ir sniegts ieskats Krievijas impērijas plānos 19. gadsimta sākumā reformēt izglītības sistēmu, parādīts, kā iecerētās reformas mainīja pastāvošo lietu kārtību Baltijas guberņās, kā arī analizēts zemnieku skolu un izglītības regulējums Vidzemes zemnieku likumā 1819. gadā. Rakstā detalizēti apskatītas likuma normas, kas nosaka zemnieku skolu tipus, organizāciju, pārvaldības, ierīkošanas un uzturēšanas jautājumus, kā arī izglītības saturu. Izsekots diskusijai muižniecības un garīdzniecības forumos – landtāgos un sinodēs, kā arī periodiskajos izdevumos par mērķiem un uzdevumiem, kādi būtu nospraužami zemnieku kārtas izglītošanā sociālo un saimniecisko pārmaiņu kontekstā pēc dzimtbūšanas atcelšanas. Hronoloģiski raksts aptver laiku no 1819. gada, kad likumdošanas ceļā tika noteikti skolu regulējumi, līdz 19. gadsimta vidum, konkrēti, 1844. gadam, kad tika izveidota Vidzemes zemnieku skolu – laukskolu jeb tautskolu pārvalde un sākās darbs pie detalizētu normatīvo aktu izveides, kas var tikt uzskatīti par pirmajām tautskolu programmām. Ar to iesākās jauns posms valdošās politiskās elites uzskatu evolūcijā un skolu politikā.
The Concept of E-Voting Mechanism Based on Law of General Election and Information Security
Authors: Sujadmiko Bayu , Panggar Iskardo P , Sofyansah Ade , Meutia Intan Fitri
Published: June 2021

The development of technology has made transformation in the world; one of them is the implementation of e-voting systems in general elections. This research aims to dig deeper into the utilization of e voting in Indonesia's general election according to the Law on General Election, and research on the e-voting safety aspect in Indonesia's general election with the Law on ITE, government regulation on One Data Indonesia, and the Bill of Personal Data Protection Law. The research method is normative, which is delivered with an analytic-descriptive method. The results show that Indonesia has arranged elections with e-voting mechanisms for multiples of times, for example, in Jembrana Regency. Based on the General Election Law, e voting could be implemented in Indonesia. However, there are still considerations in terms of technology and preparation that should prevent unwanted burden. There needs to be a regulation for voters' data management to prevent violations against human rights. Data management must pay attention to safety aspects guided by the Law on ITE, government regulation on One Data Indonesia, and the Bill of Personal Data Protection Law
Visioner er der nok af, men handlekraft?
Authors: Melander Preben
Published: June 2021

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Managementideer som en virus – hvad består det organisatoriske immunsystem af?
Authors: Madsen Søren Obed
Published: June 2021

På baggrund af Røviks virusteori (2007, 2011), virologi (Cann, 2005) og Morgans metafor for organisationer som organismer (1986), udvikler denne artikel organisatorisk virusteori til at omfatte, hvordan det organisatoriske immunforsvar fungerer. Virusteori er teorier om organisatorisk udvikling, der udforsker systemiske og politiske påvirkninger, der ændrer organisationernes livsforløb, deres praksis og eksistensberettigelse. Artiklen har tre bidrag til virusteori. For det første gør den sig nogle refleksioner om alle ideer om styring og ledelse er lige sunde for organisationer og undersøger, hvilke effekter management ideer har på organisationer. Derved bygger den videre på en tidligere artikel om strategi som virus (Obed Madsen, 2011), men udvider perspektivet ved konceptuelt at undersøge, hvordan immunforsvaret fungerer, når virussen er trængt ind i organismen. For det andet udforsker artiklen, hvilke forsvar som organisationer har mod skadelige ideer. For det tredje gør artiklen sig overvejelser om, hvordan immunforsvaret kan vedligeholdes, så vi kan sikre os sunde organisationer. Virusteori giver derfor et nyt perspektiv på et gammelt fænomen, der handler om organisatorisk udvikling og kan udfordre og kvalificere grundlæggende antagelser om management-ideer. Virusteori supplerer dermed dele af den institutionelle teori, der anser management ideer som et modefænomen, hvor det er muligt at undgå, at ideerne får en påvirkning på organisationens praksis. Denne artikels udgangspunkt er det modsatte: at ideer påvirker vores organisationer, fordi det ikke altid er muligt at dekoble sig fra dem. De inficerer os, muterer, går i dvale, inkuberer og spreder sig, hvilket har konsekvenser for vores praksis. Ligesom virus, så er det ikke alle ideer, der er godartede, og derfor bør vi overveje, hvordan vores organisatoriske immunsystem virker, samt hvordan det kan vedligeholdes.
Nitrite as a causal factor for nitrate-dependent anaerobic corrosion of metallic iron induced by Prolixibacter strains
Authors: Iino Takao , Shono Nobuaki , Ito Kimio , Nakamura Ryuhei , Sueoka Kazuo , Harayama Shigeaki , Ohkuma Moriya
Published: June 2021

Microbially influenced corrosion (MIC) may contribute significantly to
overall corrosion risks, especially in the gas and petroleum industries.
In this study, we isolated four Prolixibacter strains, which belong to
the phylum Bacteroidetes, and examined their nitrate-respiration- and
Fe0-corroding activities, together with two previously isolated
Prolixibacter strains. Four of the six Prolixibacter strains reduced
nitrate under anaerobic conditions, while the other two strains did not.
The anaerobic growth of the four nitrate-reducing strains was enhanced
by nitrate, which was not observed in the two nitrate-non-reducing
strains. When the nitrate-reducing strains were grown anaerobically in
the presence of Fe0 or carbon steel, the corrosion of the materials was
enhanced by more than 20-fold compared to that in aseptic controls. This
enhancement was not observed in cultures of the nitrate-non-reducing
strains. The oxidation of Fe0 in the anaerobic cultures of
nitrate-reducing strains occurred concomitantly with the reduction of
nitrite. Since nitrite chemically oxidized Fe0 under anaerobic and
aseptic conditions, the corrosion of Fe0- and carbon-steel by the
nitrate-reducing Prolixibacter strains was deduced to be mainly enhanced
via the biological reduction of nitrate to nitrite, followed by the
chemical oxidation of Fe0 to Fe2+ and Fe3+ coupled to the reduction of
nitrite.
Phase I randomized, placebo-controlled, cross-over dose-finding pharmacokinetic study of Coenzyme Q10 during one cycle of doxorubicin treatment for breast cancer.
Authors: Greenlee Heather , Crew Katherine , Maurer Matthew , Kalinsky Kevin , Cremers Serge , Naini Ali , Tsai Wei Yann , Shi Zaixing , Brogan Frances , Hershman Dawn
Published: June 2021

Aim: To determine the safety of Coenzyme Q10 (CoQ10) in breast cancer
patients receiving doxorubicin treatment. Methods: Phase I randomized,
placebo-controlled, cross-over, dose-finding pharmacokinetic study among
women with stage I-III breast cancer receiving 4 cycles of doxorubicin
plus cyclophosphamide. The study was designed to test the maximum
tolerated dose of CoQ10 using up to 1200 mg/day. Eligible patients were
randomized to Arm A (CoQ10 after Cycle 3, followed by placebo after
Cycle 4) or Arm B (placebo after cycle 3, followed by CoQ10 after cycle
4). CoQ10 concentrations and total antioxidant capacity (TAC) were
measured before and after chemotherapy cycles. Non-compartmental
pharmacokinetic parameters of doxorubicin and its active metabolites
were measured with and without CoQ10. Paired t-tests assessed
intra-patient differences in pharmacokinetic parameters, serum CoQ10
concentrations, TAC and adverse events. Results: Six patients received
300 mg/day of CoQ10 [Arm A (n=3), Arm B (n=3)]. One patient received
600 mg/day of CoQ10 but was discontinued due to non-adherence. Serum
CoQ10 concentrations were increased in patients receiving 300 mg/day
(mean±SD change: CoQ10, 1.6±0.9 ug/mL; placebo, -0.01±0.3 ug/mL;
P=0.01). There were no clinically significant pharmacokinetic
interactions between 300 mg/day CoQ10 and doxorubicin and no differences
in TAC or adverse events during treatment and nontreatment periods. The
trial was closed early due to slow accrual. Conclusions: 300 mg/day of
CoQ10 with doxorubicin did not change doxorubicin pharmacokinetics and
was not associated with treatment-related adverse events. Future studies
should evaluate the long-term effects of CoQ10 at 300 mg/day and safety
studies should examine higher doses.
Efficacious Tactics, Mechanics and Heuristics for Progressive Social Engineering
Authors: Dhami Ujas
Published: June 2021

With increasing digitalization and company infrastructure over the
years, the attack vectors in computer security have been enormously
metastasizing. In scope, several breaches and intrusions have been
dominantly carried out by one common tactic, Social Engineering. The
domain has gained momentum over the years in successful compromisation
of assets. Metrically, Social Engineering proportionately, has been
considered one of the most dangerous weapons of any threat actor and
consecutively, one of the most dangerous threats to any company’s human
resources. As per Cobalt’s Cybersecurity Statistics of 2021, 61% of
organizations globally, have faced breaches carried out by Social
Engineering attacks. Moreover, proofproint 2021 State of the Phish
Report recognizes Social Engineering attacks as emerging attacks with
devastating potential. These type of attacks are often undervalued by
employees and the IT staff for majority of the companies. This paper
will brief about the new tactics I used, as a threat actor, endeavouring
to make the most out of a persuasive conversation, involving (i)
physical hooking, (ii) telephonic attacks, and (iii) neuro-anatomical
deductions briefing how the existing Social Engineering attacks can
emulate the neurochemical processes inside the brain.
Safe implementation of index telephone clinic appointments for patients with suspected lower gastrointestinal cancer with concurrent financial and environmental benefits.
Authors: Wanigasooriya Kasun , Sarma Diwakar , Woods Peter , O'Connor Paul , Matthews Adrian , Aslam Muhammad Imran , Dando Carolyn , Ferguson Henry , Francombe James , Lal Neeraj , Murphy Paul , Papettas Trifonas , Ramcharan Sean , Busby Karen
Published: June 2021

Aims: The COVID-19 pandemic led to hospitals in the United Kingdom
substituting face-to-face (FtF) clinics with virtual clinic (VC)
appointments. We evaluated the impact of virtual two-week wait (2-ww)
lower gastrointestinal (LGI) consultations on stakeholders at a district
general hospital in England. Methods: Patients undergoing index
outpatient 2-ww LGI clinic assessment between 01/06/2019-31/10/2019 (FtF
group) and 01/06/2020-31/10/2020 (VC group) were identified. Relevant
data were obtained using electronic patient records. Compliance with
national cancer waiting time targets (WTT) was assessed. Environmental
and financial impact analyses were performed. Results: In total, 1531
patients were analysed (median age=70, male=852, 55.6%). Of these, 757
(49.4%) were assessed virtually via telephone; the remainder were seen
FtF (n=774, 50.6%). Ninety two (6%, VC=44, FtF=48) patients had
malignant pathology and 64 (4.2%) had colorectal cancer (CRC); of
these, 46 (71.9%, VC=26, FtF=20) underwent treatment with curative
intent. The median waiting times to index appointment, investigation and
diagnosis were significantly lower following VC assessment
(p<0.001). The cancer detection rates (p=0.749), treatments
received (p=0.785) and median time to index treatment for CRC patients
(p=0.156) were similar. A significantly higher proportion of patients
were seen within two weeks of referral in the VC group
(p<0.001). VC appointments saved patients a total of 9288
miles, 0.7 metric tonnes of CO2 emissions and £7482.97. Taxpayers saved
£80,242.00 from VCs. No adverse events or complaints were reported in
the VC group. Conclusion: Virtual 2-ww LGI clinics were effective, safe
and were associated with tangible environmental and financial benefits
for stakeholders.
Cardiac Tissue Factor Regulates Inflammation, Hypertrophy and Heart Failure in Mouse Model of Type 1 Diabetes
Authors: Cibi Dasan Mary , Sandireddy Reddemma , Bogireddy Hanumakumar , Tee Nicole , Ghani Siti Aishah Binte Abdul , Singh Brijesh K. , Mackman Nigel , Singh Manvendra K. , Singh Anamika
Published: June 2021

Diabetes patients
have an increased risk of heart failure (HF). Diabetes is highly prevalent in HF with preserved ejection fraction
(HFpEF), which is on the rise worldwide. The role of diabetes in HF is less
established and available treatments of HF are not effective in HFpEF patients.
Tissue factor (TF), a transmembrane receptor, plays an important role in immune-cell
inflammation and atherothrombosis in diabetes. However, its role in diabetes-induced
cardiac inflammation, hypertrophy, and HF has not been studied. Here, we have
utilized Wildtype (WT), heterozygous, and Low-TF (with 1% human TF) mice to
determine TF’s role in Type1 diabetes-induced
HF. We found significant upregulation of cardiac TF mRNA and protein levels in
diabetic WT hearts compared to non-diabetic controls. WT diabetic hearts also
exhibited increased inflammation and cardiac hypertrophy versus controls. However,
these changes in cardiac inflammation and hypertrophy were not found in
diabetic Low-TF mice compared to their non-diabetic controls. TF deficiency
was also associated with improved
cardiac function parameters suggestive of HFpEF, which was evident in diabetic
WT mice. The TF regulation of inflammation and cardiac remodeling was further
dependent on downstream ERK1/2 and STAT3 pathways. In summary, our study
demonstrated an important role of TF in regulating diabetes-induced
inflammation, hypertrophy, and remodeling of the heart leading to HF with
preserved ejection fraction.
The Hidden Heritage of Ankara Citadel: an Ambigous Future between Conservation and Transformation
Authors:   Ankara Yildirim Beyazit University, Ismail Salah
Published: June 2021

Although Ankara gained international attention mainly after its declaration as Capital of the Turkish Republic in 1923, the city hosts many buildings and monuments from different historical eras. The remains of Roman, Byzantine, Seljuk and Ottoman Empires discovered in the center of the city, clearly bear witness to the rich and diverse heritage of the capital. However, this heritage appears as less documented, studied and even not properly conserved. The citadel of Ankara, which dominates the narrow streets of the old city has withstood its long history very well and today houses a small neighborhood made up of valuable Ottoman wooden buildings. The link to the Roman and Medieval periods is still tangible. The Roman theatre remains at the foot of the hill are still observable, while the stone columns and beams used in the construction of the walls in a later era. The aim of this paper is to document and present the different historical eras of the castle, focusing on the remains of the medieval era. Analyzing the key features of the castle and the previous intervention on it will support the identification of the potentials of the site. Finally, recommendations for future work of architectural preservation will be elaborated on the basis of national and international conservation guidelines.
Economic accessibility of food in the context of a new global challenge
Authors: Reshetnikova Elena Gennadievna
Published: June 2021

The article deals with the study of the mechanism ensuring the economic accessibility of food, substantiating the areas for improving its most important blocks associated with the transformation of state revenue and tax policy, and the development of market mechanisms forming affordable prices for food products. The study aimed to substantiate the ways to adapt the mechanism ensuring the economic accessibility of food in the context of the new global challenge associated with the COVID-19 pandemic. The authors have considered the theoretical, methodological, and institutional aspects of ensuring the economic accessibility of food through state support of consumer demand in the context of declining actual revenues, increasing unemployment, and problems in the field of small business caused by the impact of a new global challenge.
Trends in developing the jury institution in the Russian Federation
Authors: Pshava Veronika Viktorovna , Babenko Irina Andreyevna , Pletnev Vyacheslav Vitalievich , Sokolov Aleksandr Borisovich , Sadikova Julia Vladimirovna
Published: June 2021

The article considers various forms of participating in the administration of justice in criminal cases in the constituent entities of the Russian Federation, the Federal Republic of Germany and the United States of America. A 30-year long development of the jury institution in Russia and its active reforming since 2016 necessitate a scientific analysis of various forms of people's participation, identification of their features, positive and negative experience. Despite the expanded jurisdiction of the jury considering criminal cases, the introduction of this institution at the level of district courts and the reduction of jury members, there is an acute issue of forming jury boards (the unwillingness of citizens to participate in the administration of justice) and a large number of repealed sentences passed in this form of legal proceedings. The positive experience of other democratic federal states can serve as an example of ensuring the functioning of the jury institution in Russia.
The new laws in the order of formation of the federation council of the federal assembly of the Russian Federation
Authors: Adygezalova Gyulnaz Eldarovna , Kovtun Olga Andreevna , Tereshchenko Natalia Dmitrievna , Dzidzoev Ruslan Mukharbekovich , Shapiro Irina Valerievna
Published: June 2021

The purpose of this work is to study the constitutional and legal basis for the formation of the Upper House of the Federal Parliament in connection with the adoption of the Law of the Russian Federation on the Amendment to the Constitution of the Russian Federation of March 14, 2020, No. 1-FKZ "On Improving the Regulation of Certain Aspects of the Organisation and Functioning of Public Authority". Thus, the method of analyzing legal documents allowed concluding the gradual legal consolidation of the order of formation of the Federation Council of the Federal Assembly of the Russian Federation in the conditions of building a legal democratic state. Having studied the theoretical and legal aspects of the formation of the Federation Council, the authors note that the current order reflects the socio-political realities, corresponds to the foundations of the constitutional system, and allows for a more complete reflection of the constitutional foundations of democracy, popular representation, and the principles of parliamentarism.
Tackling hypoglycemia in children: teams, targets and technology
Authors: Danne Thomas
Published: June 2021

On the occasion of the Somogyi Award lecture this review focusses on the current advances in tackling hypoglycemia in pediatric patients with type 1 diabetes providing evidence for the importance of multidisciplinary teams, ambitious glycemic targets and implementation of diabetes technology. Meal-related intensified insulin replacement with differential substitution of basal- and bolus insulin is the therapy of choice in the care of children and adolescents with type 1 diabetes. The use of insulin pumps and continuous glucose monitoring devices is increasing rapidly, with the type of insulin therapy (insulin pen or pump) depending on the age of the patients and family preference. Education appropriate to the age and current challenges is essential for the children's participation in everyday life as undisturbed as possible. New parameters like time in range and time below range suitable for identifying high glycemic variability as risk factor for severe hypoglycemia complement the HbA1c targets and the ambulatory glucose profile (AGP) in a shared decision making on therapeutic adjustments between the diabetes team and people with diabetes. Automated insulin delivery as a hybrid closed loop or dosing advice using artificial intelligence are becoming a clinical reality. However, diabetes education as a team approach, defining clear targets with outcomes evaluated in multinational registries like SWEET remain important for shaping the future of pediatric diabetology.
GLP-1-receptoragonista-kezelés diabeteses vesebetegségben
Authors: Fülöp Gábor , Dezső László , Wittmann István
Published: June 2021

A közlemény a glukagonszerű peptid-1 receptoragonistáinak (GLP-1-RA) a vesekimenetelre gyakorolt hatását tárgyalja 2-es típusú cukorbetegségben. A diabeteses vesebetegség, amelyet a csökkenő glomeruláris filtrációs ráta és a fokozott vizeletfehérje-ürítés jellemez, gyakori szövődménye a cukorbetegségnek. A diabetes a fő oka a krónikus vesebetegségnek és a végstádiumú veseelégtelenségnek. A diabeteses vesebetegség független kockázati tényezője a szív-érrendszeri betegségeknek. A diabeteses vesebetegség kórfolyamata összetett, többtényezős. Ilyenek a hyperglykaemia, a magas vérnyomás, a dyslipidaemia, elhízás, inzulinrezisztencia, magas húgysavszint, amelyek hozzájárulhatnak a vese glomeruláris és tubuláris károsodásához. A STENO-2 vizsgálatban a több támadáspontú gyógyszeres beavatkozás – törekedve a glykaemiás státusz javítására, a vérnyomás csökkentésére, a dyslipidaemia javítására – jobb kimenetelhez vezetett diabeteses vesebetegségben, de a vesebetegség reziduális kockázata magas maradt. Az újabb antidiabetikumcsoport, a GLP-1-receptoragonisták kedvező hatást mutatnak a kardiovaszkuláris betegségek és a diabeteses vesebetegség kimenetelére. A GLP-1-receptoragonistákkal végzett kardiovaszkuláris biztonságossági vizsgálatok másodlagos, feltáró jellegű vesevégpontjai a GLP-1-RA-k vesevédő hatására utalnak, azonban a GLP-1-RA-k renális hatását kemény vesevégpontokon még nem igazolták.
MANAJEMEN ASUHAN KEBIDANAN PADA NY ”M” DENGAN PERDARAHAN POSTPARTUM PADA TANGGAL 12 SEPTEMBER S.D. 25 OKTOBER DI RSUD SYEKH YUSUF GOWA TAHUN 2019
Authors: Sahid Riski , Darmawansyih Darmawansyih
Published: June 2021

Pendahuluan Perdarahan Postpartum merupakan penyebab kematian terbesar pada ibu yang ditandai dengan kehilangan darah lebih dari 500 ml. Salah satu penyebab Perdarahan yaitu Retensio Plasenta. Retensio Plasenta adalah tertinggalnya Plasenta di dalam uterus 30 menit setelah bayi lahir yang menyebabkan Perdarahan dan perlu dilakukan tindakan segera seperti Manual Plasenta. Metode Karya tulis ilmiah ini bertujuan untuk melaksanakan Manajemen Asuhan Kebidanan pada Ibu dengan Perdarahan Postpartum di RSUD Syekh Yusuf Kabupaten Gowa Tahun 2019 sesuai dengan 7 langkah Varney dan SOAP. Hasil Penanganan yang diberikan kepada Ibu dengan Retensio Plasenta yakni dengan melakukan tindakan pemasangan infus RL + drips Oxytosin 2 ampl, kolaborasi dengan dokter untuk melakukan Manual plasenta, pemberian antibiotik, melakukan Pemeriksaan USG serta memantau Kala IV di RSUD Syekh Yusuf Kab. Gowa Tahun 2019 Kesimpulan dari studi kasus dengan Manajemen Asuhan Kebidanan 7 Langkah Varney dan SOAP yakni dari hari pertama sampai hari ketiga berlangsung normal yang ditandai dengan Plasenta dapat lahir tanpa ada sisa Plasenta, anemia teratasi, syok tidak terjadi, tanda-tanda infeksi tidak tampak serta tanda-tanda vital dalam batas normal. Maka dapat disimpulkan bahwa tidak ada kesenjangan antara tinjauan kasus dan tinjauan teori.