bluuebunny/crossref_metadata_2025 huggingface dataset:
Safety of Repeated Administration of Xenogeneic Human Apoptotic State (Allocetra-Ots) in Sprague Dawley Rats
Authors: Ankri Chen , Hershkovitz Oren , Hershkovitz Liat , Brami Meital , Levy Ronnie , Sarig Hadar , Souli Einat , Reicher Barak , Amor-Baroukh Veronique , Mevorach Dror , Nyska Abraham
Published: March 2024

Apoptotic cells possess immunomodulatory effects that can be utilized to treat imbalanced immune conditions. Information on the preclinical safety of such treatment is sparse. In this study, the safety of apoptotic cells (Allocetra-OTS) was assessed in a GLP toxicological study on Sprague Dawley rats. Three doses of Allocetra-OTS or vehicle were administered intravenously (IV) for 3 consecutive days. Animals in the Main study were sacrificed on day 4, while animals from the Recovery groups were kept for 14 or 28 days. Allocetra-OTS was well tolerated, and no adverse effects were observed in body weight, clinical signs, food consumption or ophthalmologic observation. Thus, the No Observed Adverse Effect Level (NOAEL) dose was determined as the highest dose administered. An observed elevation in immune cells was suspected to be due to Allocetra-OTS; similarly to other clinical chemistry parameters, however, it was resolved in the Recovery phases. Splenomegaly and a dose-related Extramedullary Hematopoiesis (EMH) in the red pulp were observed, with no adverse events, and were considered to be a normal and expected reaction following IV administration of cell-based therapies. In conclusion, under the conditions of this study Allocetra-OTS was concluded to be safe, further supporting its potential candidacy for clinical studies
Experience Economy Perspective on Recreational Fishing Tourism Travelers’ Reviews: A Data Science Approach
Authors: Yfantidou Georgia , Yfantidou Sofia , Karanatsiou Dimitra , Liontakis Angelos , Maniopoulou Mairi , Balaska Panagiota , Papaioannou Alkistis , Vassilopoulou Vassiliki
Published: March 2024

This study explores the Experience Economy dimensions within fishing tourism, adopting a data science perspective by employing web crawling for extensive data gathering on reviewer profiles from TripAdvisor. Utilizing Natural Language Processing (NLP) techniques, it scrutinizes the relationship between Experience Economy dimensions and user profiling aspects. Findings reveal "Entertainment" as the predominant dimension in tourist reviews, followed by "Aesthetic," "Educational," and "Escapist." Particularly notable are the frequent co-occurrences of "Entertainment"-"Aesthetic" and "Educational"-"Entertainment" pairs. The practical implications underscore the potential socioeconomic benefits of fishing tourism for local communities and fishermen, emphasizing the necessity for governmental support in terms of infrastructure, leadership, legislation, and financial backing to foster sustainable development in this sector. Notably, this research stands as a pioneering effort in its focus on Experience Economy dimensions and user profiling within the context of fishing tourism, drawing data from business pages and user profiles.
Prediction and Transition of Vegetation Vulnerability in the Mara River Basin under Different SSP Scenarios
Authors: Zhu Wanyi , Zhang Zhenke , Feng Shouming , Ren Hang
Published: March 2024

The Mara River basin (MRB) has a world-famous ecosystem, but the vegetation has been damaged due to economic development in recent years, and there is little known about the area that will experience severe vegetation damage in the future. Based on the vegetation vulnerability system, principal component analysis, and three CMIP6 scenarios (SSP1-2.6, SSP2-4.5, SSP5-8.5), vegetation vulnerability was calculated in the base period (2010-2019), near-term period (2020-2059) and long-term period (2060-2099) in the MRB. The spatial cluster of vegetation vulnerability was revealed by spatial correlation analysis, and the transition of vegetation vulnerability of different periods was analyzed by stochastic matrix. The results showed that in all periods, the vulnerability showed a high-high cluster in the east, and a low-low cluster midstream and downstream. From the stochastic matrix, the area of high vulnerability increased the least under the SSP1-2.6, while it increased the most under the SSP5-8.5. The vegetation vulnerability upstream increased the most from the base period to the near-term period and long-term period in the MRB. By comparing the vegetation vulnerability under different scenarios, and pointing out the areas with the highest vulnerability increase, this study can better provide comprehensive decision-making for vegetation protection in the MRB.
Research on Fault Detection by Flow Sequence Algorithm with Deep Learning Model for Industrial Internet of Things
Authors: Lei Dongfeng , Zhao Liang , Chen Dengfeng
Published: March 2024

Classifying network flow subsequences in an Industrial IoT gateway is an effective method for identifying Industrial IoT faults. This paper proposes a subsequence classification algorithm SSGBUL-IKNN based on unsupervised learning encoding to address the problem of low classification accuracy. Firstly, we built a network module based on unsupervised learning to encode the flow sequence of the Industrial IoT gateway. In the encoding module, a subsequence calibration algorithm controls the increasing error during the coding process. Then, the specific fault type is obtained through an improved KNN classification algorithm based on the indication distance source from the integrated coding sequences converted by multi-dimensional network flow sequences. The test result on three Industrial IoT datasets of a sewage treatment plant shows that the accuracy of SSGBUL-IKNN in this paper exceeds 92%, significantly higher than the algorithm DTW and TSF. It reaches the classification requirements of Industrial IoT fault diagnosis.
Intraphagosomal Free Ca2+Changes during Phagocytosis
Authors: Hallett Maurice B. , Dewitt Sharon , Laffafian Iraj , Lewis Kimberly J , Green Joanna
Published: March 2024

Phagocytosis (and endocytosis) is an unusual cellular process which results in the formation of a novel subcellular organelle, the phagosome. This phagosome contains not only the internalised target of phagocytosis, but also the external medium, creating a new border between extracellular and intracellular environments. The boundary at the plasma membrane is, of course, tightly controlled and exploited in ionic cell signalling events. Although there has been much work on the control of phagocytosis by ions, notable Ca2+ ions influxing across the plasma membrane, increasing our understanding of the mechanism enormously, very little work has been done exploring the phagosome/cytosol boundary. In this paper, we have explored the changes in the intra-phagosomal Ca2+ ion content which occur during phagocytosis and phagosome formation in human neutrophils. Measuring Ca2+ ion concentration in the phagosome is potentially prone to artefacts as the intra-phagosomal environment experiences changes in pH and oxidation. However, by excluding such artefacts, we conclude that there are open Ca2+ channels on the phagosome, which allow Ca2+ ions to ‘drain’ into the surrounding cytosol. This conclusion was confirmed by monitoring the translocation of intracellularly expressed YFP-tagged C2 domain of PKC-γ. This approach marked regions of membrane at which Ca2+ influx occurred, the earliest being the phagocytic cup, and then the whole cell. This paper therefore presents data which has novel implications for understanding phagocytic Ca2+ signalling events, such as peri-phagosomal Ca2+ hotspots, and other phenomena.
Predicting the Occurrence of Forest Fire in the Central-South Region of China
Authors: Hai Quansheng , Han Xiufeng , Vandansambuu Battsengel , Bao Yuhai , Gantumur Byambakhuu , Bayarsaikhan Sainbuyan , Chantsal Narantsetseg , Sun Hailian
Published: March 2024

Grasping the spatial and temporal patterns of forest fires, along with the key factors that drive them and the ability to forecast such events accurately, is essential for the successful management of forests. In China's southern region, forest fires significantly endanger the ecological system, public safety, and economic well-being. Through the application of Geographic Information Systems (GIS) and LightGBM (Light Gradient Boosting Machine) model, this study investigates the determinants of fire incidents and formulates a predictive model for forest fire occurrences, alongside a zoning strategy, within the Central-South area. The results indicate: (i) Spatially, fire points exhibit significant clustering and autocorrelation characteristics; (ii) The Central-South Forest Fire Prediction Model shows exceptional accuracy, reliability, and predictive power, with high performance metrics across training and validation sets, including over 85% accuracy, precision, recall, and F1 scores, along with AUC values above 89%, underscoring its efficacy in forecasting forest fires and distinguishing between fire events; (iii) Throughout the year, forest fire risks in the Central-South region of China vary by region and season, with risk spikes from March to May in Guangdong, Guangxi, Hunan, Hubei, and Hainan. From June to August, localized risks are observed in Heyuan and Huangshi, while from September to November, an increase in risk is noted in Guangdong (Meizhou, Heyuan, Shaoguan), Guangxi (Nanning, Hezhou, Yulin), and Hunan (Binzhou, Yongzhou, Hengyang) due to cooler, drier conditions and leaf litter accumulation. From December to February, the risk continues in specific areas across Guangdong, Guangxi, Hunan, and Hubei.
Navigating The Terrain of Digital Transition: Ghana’s Journey of Developing a Digital Land Information System
Authors: Owusu Ansah Rosemond , Abubakari Zaid , Quaye Benjamin Armah , Todorovski Dimo , Lemmen Christiaan
Published: March 2024

This paper explores Ghana's two-decade journey in developing a digital land information system (LIS), exemplified by Ghana Enterprise Land Information System (GELIS) and Enterprise Land Information System (ELIS). Despite advancements by Ghana’s Lands Commission, manual processes persist and coexist with digital ones. Our study uses a qualitative approach to assess the effectiveness of the LIS implemented in Accra. The study found that Accra’s LIS is highly aligned with clear institutional mandates, roles, and responsibilities as well as the availability of laws and policies to support analogue to digital conversion. Furthermore, a robust approach for protecting data, operating system and software underpins the system. Subsequently, the integration of a digital LIS has enhanced service delivery and accountability. Nonetheless, Accra’s LIS is still at the beginning of a comprehensive learning and development curve. To sustain the LIS requires furtherance in the implementation plan, funding, law implementation, ICT strategy, divisional integration, work processes, data quality, and communication strategy. These findings will inform the next steps of improvement for Accra's LIS and guide its nationwide scaling, contributing to discussions on technology acceptance dynamics in predominantly analogue environments.
Towards a Long-Term UAV Monitoring Framework/Strategy for Post-mining Effects: Prosper-Haniel Case
Authors: Pawlik Marcin , Haske Benjamin , Flores Hernan , Bernsdorf Bodo , Rudolph Tobias
Published: March 2024

Direct and indirect effects after mine operations cease must ideally be subject to perpetual monitoring routines in order to detect possible risks or avoid adverse effects on the surrounding ecosystems at an early stage. In this contribution, mining subsidence lakes created inside the nature reserve Kirchheller Heide and Hilsfeld Forest are subjected to analysis for a long-term monitoring scheme. For this purpose, we employ high-resolution unmanned aerial system (UAS)-based multispectral and thermal mapping tools to provide a fast, non-invasive and multitemporal environmental monitoring method. Specifically, we propose to monitor vegetation evolution through multispectral analysis, biotypes identification using machine learning algorithms, and water surface extent detection, together with their thermal behavior. The aim of this contribution is to present the proposed workflow and first results to establish a baseline for future analyses and subsequent surveys for longterm multi-temporal monitoring
Resumes Classification Using Neural Network Approaches Combined with Bert and Gensim: CVS of Moroccan Engineering Students
Authors: Qostal Aniss , Moumen Aniss , Lakhrissi Younes
Published: March 2024

Deep Learning (DL) oriented document processing is widely used in different fields for extraction, recognition, and classification processes from raw corpora of data. The article examines the application of deep learning approaches, based on different neural network methods, including Gated Recurrent Unit (GRU), Long Short-Term Memory (LSTM), and Convolutional Neural Networks (CNN). The compared models were combined with two different word embedding techniques, namely: Bidirectional Encoder Representations from Transformers BERT and Gensim Word2Vec. The models are designed to evaluate the performance of architectures based on neural network techniques for the classification of CVs of Moroccan engineering students at ENSAK(National School of Applied Sciences of Kenitra, Ibn Tofail University). The used dataset included resumes collected from engineering students at ENSAK in 2023 for a project on the employability of Moroccan engineers in which new approaches were applied, especially machine learning, deep learning, and big data. Accordingly, 867 resumes were collected from five specialties of study (Electrical Engineering, Networks and Systems Telecommunications, Computer Engineering, Automotive Mechatronics Engineering, Industrial Engineering). The results revealed good performance of the proposed models based on the BERT embedding approach compared to models based on the Gensim Word2Vec embedding approach. Accordingly, the CNN-GRU/Bert model achieved slightly better accuracy with 0.9251 compared to other hybrid models.
Packet Scheduling Algorithms in LTE/LTE-A
Authors: Ranswal Shubham
Published: March 2024

Cellular Technology came into existence in Japan in 1979. From that time, we have seen many advances in technology. Currently, most of the person uses either 4G or 5G, among which 5G is a newer technology. 4G network was the first network to use LTE. LTE stands for Long Term Evaluation. Most people get confused between 4G and LTE, they assume both to be the same. In reality, LTE has evolved on the 4G technology. It was first introduced in 2008 to provide higher efficiency and data rates to the cellular network. It was designed to evolve the performance of the networks which includes the evolution of hardware components, optimization of software, power and cost efficiency. This work presents a study on LTE, LTE-A and VoLTE technology. We also discussed about the several packet scheduling algorithms that are being used for transmission of packets. It brings out new opportunities for the researchers to work on increasing the efficiency of those algorithms by modifications.
Functional Analysis of Forkhead Transcription Factor Fd59a in Spermatogenesis of Drosophila melanogaster
Authors: Tang Ting , Pei Mengyuan , Xiao Yanhong , Deng Yingshan , Lu Yuzhen , Yu Xiao-Qiang , Wen Liang , Hu Qihao
Published: March 2024

Spermatogenesis is critical for insect reproduction and is regulated by many different genes. In this study, we found that Forkhead transcription factor Fd59a functions as a key factor in spermatogenesis of Drosophila melanogaster. Fd59a contains a conversed Forkhead domain, and it is clustered to the FoxD subfamily with other FoxD members from some insect and vertebrate species. Mutation in Fd59a caused swelling in the apical region of the testis. More importantly, only a few mature sperm were present in the seminal vesicle of Fd59a mutant flies compared to the control flies, and the fertility of Fd59a2/2 mutant males was significantly lower than that of the control flies. Immunofluorescence staining showed that the homeostasis of testis stem cell niche in Fd59a2/2 mutant and Fd59a RNAi flies was disrupted, and apoptosis of sperm bundles was increased. Furthermore, results from RNA-sequencing and qRT-PCR suggest that Fd59a can regulate expression of genes related to reproductive process and cell death. Taken together, our results indicated that Fd59a plays a key role in the spermatogenesis of Drosophila.
Analysis of Intensity Limits for Light Emitting Diodes Used in Toys and Consequences for Children's Visual Health
Authors: Martinsons Christophe , Enouf Olivier , Behar-Cohen Francine , Torriglia Alicia , Vienot Francoise , Attia Dina
Published: March 2024

The analysis of the current safety standards for electric toys showed that the normative intensity limits for visible light emitted by LEDs integrated in toys are overestimated. These limits were originally set in a scientific article published in 2012 that was adapted into the international safety standard published in 2017, and into the subsequent European and national standards, all published in 2020. The overestimation of the intensity limits results from several errors made in the original article. Accordingly, the current normative intensity limits for visible light used in toys do not protect the children’s eyes against adverse effects of exposure to high intensity LEDs which may compromise their visual health. Updating the safety standards for electric toys using a method based on robust scientific data is recommended to protect children's visual health and ensure their long-term well-being.
Renaming ‘Chemosensory’ Proteins (CSPs): ‘Lipoid-Binding Proteins’ — Molecular Nomenclature, Structure, Expression, Evolution, and Intracellular Functions
Authors: Liu Guoxia , Sun Botong , Fan Wei , Yue Shousong , He Qiuxia , Picimbon Jean-François
Published: March 2024

This is a brief critique of the functions—particularly olfactory functions—specified for the “Chemosensory Protein” (CSPs) molecule family. On the basis of these proteins’ presence in the sensory antennal lymph of locusts, odor chemosensory ligand binding functions have been hypothesized. According to this hypothesis, the entire protein molecule superfamily is referred to as “CSPs”. However, new information and developments in the field of CSP molecular research, such as the expression of CSP genes in the gut, brain, fat body, wings, epidermis, and pheromone gland, as well as gene expression profiling from most early developmental stages—that is, CSP expression well in advance of the appearance of chemical sense nerve cells—strongly suggest that the protein molecule has other roles that are unrelated to chemosensing. Moreover, CSPs are found in bacterial microbial prokaryote organisms in addition to insects and all other arthropods. Thus, we examine the molecule’s name, definition, RNA editing, protein structure, lipid binding properties, DNA interaction, and evolutionary characteristics in brief before referring to this protein family as “Chemosensory Proteins”. As a means of renaming this protein family, this review article discusses the latest findings (“CSP” is attached to the tail of bigger intracellular proteins) and attempts to compel all the data. Because of its highly conserved molecular distinctive feature (four adjacent cysteines), we propose renaming “CSPs” as “4CSPs” (4 Cysteines Soluble Proteins) and use at least for abbreviations for distinctive animal proteins the common peptide 5-letter code, such as “Bommo-4CSPs”.
Fluoxetine and Sertraline Potently Neutralize the Replication of Distinct SARS-CoV-2 Variants
Authors: Thümmler Laura , Beckmann Nadine , Sehl Caroline , Soddemann Matthias , Braß Peer , Bormann Maren , Brochhagen Leonie , Elsner Carina , Hoertel Nicolas , Cougoule Céline , Ciesek Sandra , Widera Marek , Dittmer Ulf , Lindemann Monika , Horn Peter A. , Witzke Oliver , Kadow Stephanie , Kamler Markus , Gulbins Erich , Becker Katrin Anne , Krawczyk Adalbert
Published: March 2024

The pandemic caused by SARS-CoV-2 is still a major health problem. Newly emerging variants and long-COVID-19 represent a challenge for the global health system. In particular, individuals in developing countries with insufficient health care need easily accessible, affordable and effective treatments of COVID-19. Previous studies have demonstrated the efficacy of functional inhibitors of acid sphingomyelinase (FIASMA) against infections with various viruses, including early variants of SARS-CoV-2. This work investigated whether the acid sphingomyelinase inhibitors fluoxetine and sertraline, usually used as antidepressant molecules in clinical practice, can inhibit the replication of the former and recently emerged SARS-CoV-2 variants in vitro. Fluoxetine and sertraline potently inhibited the infection with pseudotyped virus like particles and SARS-CoV-2 variants D614G, alpha, delta, omicron BA.1 and omicron BA.5. These results highlight fluoxetine and sertraline as priority candidates for large-scale phase 3 clinical trials at different stages of SARS-CoV-2 infections, either alone or in combination with other medications.
Eco-Friendly Microencapsulation of Lacticaseibacillus Paracasei Using Cissampelos pareira Leaf Extract as Natural Encapsulating Materials
Authors: Vimon Sasi , Romyasamit Chonticha , Chanpakdee Rawiwan , Boonplu Sumaree , Nuengjamnong Chackrit , Makkliang Fonthip , Sangkanu Suthinee , Nissapatorn Veeranoot , Saengsawang Phirabhat , Dalgaard Tina S. , Mitsuwan Watcharapong
Published: March 2024

Microencapsulation using polymer materials is a potent process to protect and prolong the survival of probiotics. Cissampelos pareira leaf contains natural gelling agents that possess solidifying properties. This study aimed to investigate the development of microencapsulation containing Lacticaseibacillus paracasei using C. pareira extract as a natural encapsulating material. The absorption bands near 1603 cm−1 and 1725 cm−1 detected by Infrared spectroscopy (FTIR) were identified as pectin in C. pareira structure. The L. paracasei-C. pareira microcapsules (LP-CP) showed high encapsulation efficiency by 90.5% which was confirmed by the evaluation of their survival rate. Under thermal conditions (85oC), bacterial viability detected in the microcapsules was 69% as opposed to non-encapsulated bacteria where viability was as low as 5%. Furthermore, the microcapsule presented 75% bacterial viability whereas the free cells showed 30% under acidic conditions (pH 2). During storage conditions, LP-CP viability remained at 50% when the storage time was extended to 90 days whereas, the survival rate of free cells significantly decreased by 100% after 90 days. This information suggests that C. pareira is a potent polymer which can be used as an eco-friendly material for the microencapsulation of probiotics relevant as dietary supplementation for humans or animals.
Hox Gene Collinearity with Pulling Physical Forces Create a Hox Gene Clustering in Embryos of Vertebrates, Invertebrates, Complete or Split Clutters
Authors: Papageorgiou Spyros
Published: March 2024

Hox gene clusters are crucial in Embryogenesis. It was observed that some Hox genes are located in order along the telomeric to centromeric direction of the DNA sequence: Hox1, Hox2, Hox3…. These genes are expressed in the same order in the ontogenetic units of the Drosophila embryo along the Anterior-Posterior axis. The two entities (genome and embryo) differ significantly in linear size and in-between distance. This strange phenomenon was named Spatial Collinearity (SP). Later, it was observed that, particularly in the Vertebrates, a Temporal Collinearity (TC) coexists: first is Hox1 expressed, later Hox2 and even later Hox3,…,. According to a Biophysical Model (BM), pulling forces act at the anterior end of the cluster while a cluster fastening applies at the posterior end. Hox clusters are irreversibly elongated along the force direction. During Evolution, the elongated Hox clusters are broken at variable lengths thus split clusters may be created. An Empirical Rule was formulated distinguishing development due to a complete Hox cluster from development due to split Hox clusters. BM can ‘explain’ this Empirical Rule. In a spontaneous mutation where the cluster fastening is dismantled, a weak pulling force automatically shifts the cluster inside the Hox activation domain. This cluster translocation can probably explain the absence of Temporal Collinearity in Drosophila.
Nest Design and Breeding Success: Replicability of Methodologies and Research Findings in Avian Model Species
Authors: Lambrechts Marcel , Deeming Charles
Published: March 2024

Abstract: More than 40 hypotheses predict associations between features of nest architecture and at least one measure of reproductive success. However, quantitative studies of reproductive consequences of nest characteristics remain scarce. In addition, most studies were conducted on model species of which nests can be easily monitored with artificial nest-boxes. Here we review the replicability of research protocols and findings in model species with many repeat studies focusing mainly on nest-size components, animal-derived nest material, or fresh greenery in blue tits (Cyanistes caeruleus), great tits (Parus major), tree swallows (Tachycineta bicolor), and starlings (Sturnus spp.). The studies looked for correlations between nest traits and aspects of breeding performance that can be easily quantified in the field, such clutch size, brood size at hatching or fledging, the % of eggs that hatch or fledge, or nestling characteristics assumed to reflect qualities associated with survival probabilities (e.g., morphometry, body condition, blood profiles). We discuss the consequences of poor replicability of research methodologies and provide explanations for why many of these studies reported poor associations between nest design and breeding success at different spatiotemporal scales. We also make suggestions for future research.

Keywords: Nest design, Breeding success, Nest-box, Cavity-nesting birds, Replicability
Human Health Impacts of Urban Air Pollution in Cameroon
Authors: Andigema Angyiba Serge , Tania Cyrielle NGNOTOUOM NGNOKAM
Published: March 2024

It is concerning that Cameroon's urban centers are experiencing an alarming rise in air pollution as a result of urbanization, population growth, industrial activity, and transportation emissions. We examined the causes, health impacts, research methodology, case studies, and government measures to address the urgent issue of air pollution in Cameroon's urban regions. We have emphasized how Cameroon's air pollution levels have significantly increased as a result of causes like population expansion, urbanization, industrial emissions, and automobile exhaust A thorough discussion of the negative health impacts of extended exposure to air pollution is included, with special attention to the sensitivity of the old and young. These effects include respiratory disorders, cardiovascular ailments, and early mortality. We emphasized the pressing need for all-encompassing strategies to address air pollution, such as increased public awareness campaigns, stronger emissions regulations, the development of renewable energy sources, and better waste management. The techniques employed in studies on air pollution, like as epidemiological research and air quality monitoring, are also explained to provide light on the unique health dangers that Cameroonian urban dwellers must contend with. We emphasized in our conclusion the significance of joint efforts by legislators, medical professionals, and the general people to reduce air pollution and protect public health in Cameroon in order to create a cleaner and healthier future. In order to protect public health in the future, it is imperative that Cameroon's air pollution be addressed.
Port Scanning Techniques Tools and Detection
Authors: Coyle Sam
Published: March 2024

This review aims to consolidate varied information regarding Port Scanning, and examine the tools, techniques, and detection algorithms used. It explores TCP SYN, Full TCP, UDP, and stealth scans, and shows their functions and abilities. Paired with these techniques, it also shows the tools that they can be used by, such as NMap, Zmap, and MASSCAN. It discusses the various detection techniques such as Signature and Anomaly based detection, and discusses the real world impact of this technology, while commenting on the legal and ethical issues posed.
Lathyrus Aphaca Extract MnO Nanoparticles: Synthesis, Characterization, and Photocatalytic Degradation of Methylene Blue Dye
Authors: Haris Muhammad , Hassan Amir , Khan Sana Ullah , Khan Istikhar , Akif Muhammad , Akhtar Naveed
Published: March 2024

Our environment has been impacted by man-made pollutants mainly industries make substantial use of synthetic dyes which exhibit cytotoxicity and have significant environmental consequences. Effective photocatalyst-based approaches for degrading synthetic dyes into less toxic chemical are of great interest. Synthesizing NPs using biological approaches, particularly plant-based approaches offer advantages, decreasing the risk of NPs losing biocompatibility during synthesis, cost-effectiveness, and eco-friendliness. In this study, we employed a green synthesis method to produce manganese oxide nanoparticles (MnO NPs) utilizing leaf extract from the Lathyrus Aphaca plant. The synthesized MnOx NPs were characterized through various techniques; X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), Fourier-transform infrared spectroscopy (FTIR), and UV–visible spectroscopy. XRD analysis showed distinct peaks, indicated the presence crystallographic planes within the MnO2 nanoparticles, thus confirming their crystalline structure. SEM study highlighted closely packed configurations with average size of approximately ≥ 50-70 nm, with well-defined boundaries. EDX analysis showed the presence of elemental manganese (Mn) in the samples, with peaks corresponding to Mn detected at lower energy levels, predominantly represented by MnO. FTIR, showed the presence of the O-O stretching mode at a frequency of 719 cm-1, the presence of MnO6 oxides of manganese, and peak at 548 cm-1 corresponded to the Mn-O stretching mode. Furthermore, the green-synthesized manganese oxide nanoparticles exhibited promising photocatalytic and adsorption capabilities against Methylene Blue (MB) dye, leading to approximately 93.21% degradation of MB when treated with the green-synthesized MnO nanoparticles derived from plant extract. This highlights the efficacy and potential of these nanoparticles in environmental remediation applications, particularly in the degradation of methylene blue contaminants.
Improved Production of Marandu Palisade Grass (Brachiaria brizantha) with Mixed Gelatin Sludge Fertilization
Authors: Ferreira Eduardo André , De Abreu Joadil Gonçalves , Da Silva Wininton Mendes , Müller Danielle Helena , Dos Santos Dalilhia Nazaré , Cremon Cassiano , Dos Santos Weber Oscarlina Lúcia , Hoshide Aaron Kinyu , De Abreu Daniel Carneiro , Gonçalves Maybe Lopes , Júnior José Advan Pereira Pedrosa
Published: March 2024

Gelatin industry residues are increasingly used as fertilizer and soil conditioner. However, correct residue dosage is critical for grass development and minimizing environmental impacts. This randomized block design study determined adequate dosage of Mixed Gelatin Sludge (MGS) for Marandu grass production in wet/dry seasons in Brazil. Five MGS levels (0%–200% of required nitrogen) were compared to mineral fertilizer. Agronomic/productivity characteristics, bromatological composition, macro/micro-nutrient composition of leaves, and soil chemical attributes were evaluated. Agronomic/productivity characteristics were influenced by MGS dose in both dry/rainy seasons, except for leaf blade pseudostem ratio and percentage of leaves/pseudostem. Bromatological composition was influenced by MGS doses in dry/rainy seasons except for dry/mineral material quantities. Marandu leaf tissue chemical composition was significantly influenced by MGS dose, except for potassium, boron, and iron. Chemical composition of four soil layers between 0–50 cm influenced GMS dose, except for pH, organic matter, magnesium, copper, manganese, and zinc. GMS dose for Marandu production should be 200% of nitrogen (N) requirement. GMS application increased productivity/quality of Marandu grass. Macronutrients (N, phosphorus) and micronutrients (Ca, Mg, S, Cu, and Zn) increased in Marandu grass and in the soil (Ca, S, and Na). Increased sodium (Na) level was not limiting.
Vertical Transmission and Treatment of HIV/AIDS Epidemic with Saturation Dynamics Modeling
Authors: Francesco Zolar
Published: March 2024

This study presents a dynamic modeling approach to investigate the impact of saturation dynamics on HIV/AIDS transmission in the presence of vertical transmission and treatment strategies. The proposed model incorporates disease-free and endemic equilibria, with a focus on analyzing the basic reproduction number and conducting stability analysis. Results indicate that the disease-free equilibrium is locally asymptotically stable under certain conditions. The findings suggest that a combination of treatment interventions and awareness campaigns, along with other control measures, may play a crucial role in curbing the spread of the HIV/AIDS virus. This research contributes to understanding the complex dynamics of HIV/AIDS epidemics and highlights the importance of considering saturation effects in epidemic modeling.
Assessment of iodine supply of vegetarian children
Authors:   M.Gorky Donetsk National Medical University, Donetsk, Russian Federation, Nalyotov A.V. , Svistunova N.A. ,   M.Gorky Donetsk National Medical University, Donetsk, Russian Federation, Masyuta D.I. ,   M.Gorky Donetsk National Medical University, Donetsk, Russian Federation
Published: March 2024

Objective. To study the iodine supply of children on a vegetarian diet and to evaluate the effectiveness of iodized salt for the prevention of iodine deficiency. Methods. 65 vegetarian children( from 7 to 11 years) were examined. The control group included 40 healthy children of the same age which had no any dietary restrictions. All children lived in the Donetsk Republic. The study of iodine supply was carried out by determining the median of ioduria in the group. Taking into account the identified changes in the iodine supply of children of the surveyed groups, we prescribed them the prevention of iodine deficiency using iodised salt. The effectiveness was evaluated in 6 months. Results. In the main group, the median iodine was 68.4 μg/L, which is mild iodine deficiency. At the same time, 33.9% of children of the main group had a level of ioduria <50 μg / l. In the control group, the median iodine was 97.1 μg/L. Ioduria <50 μg/L had 25.0% of children. In 6 months from the beginning of iodised salt use in the main group, the median iodine was 107.8 μg/L, which is normal iodine supply, and the proportion of children with an iodine concentration in the urine <50 μg/L was 16.9%. In turn, in the control group, after preventive use, the median iodine was 122.5 μg/L, and the proportion of children with ioduria <50 μg/L decreased to 12.5%. Conclusion. The children living in the Donbass have a mild iodine deficiency. Vegetarianism without the use of iodised salt leads to an even more pronounced iodine deficiency. The received data allows to consider that vegetarian children have a risk of iodine deficiency. Regular iodized salt use is an effective prevention of iodine deficiency not only in traditionally fed children, but also in vegetarian children. Key words: vegetarianism, iodine, iodine deficiency, children, iodised salt
Vitamin D in the treatment of autoimmune diseases on the example of a clinical case of diffuse toxic goiter
Authors:   Professor Kalinchenko Clinic, Moscow, Russian Federation, Kalinchenko S.Yu. ,   Peoples' Friendship University of Russia (RUDN), Moscow, Russian Federation, Samburskaya O.V. ,   Professor Kalinchenko Clinic, Moscow, Russian Federation,   Peoples' Friendship University of Russia (RUDN), Moscow, Russian Federation, Vorslov L.O. ,   Professor Kalinchenko Clinic, Moscow, Russian Federation,   Peoples' Friendship University of Russia (RUDN), Moscow, Russian Federation, Sviderskaya T.A. ,   Professor Kalinchenko Clinic, Moscow, Russian Federation
Published: March 2024

The article presents a rare clinical case of treatment of diffuse toxic goiter with the use of antioxidant preparations, preparations containing cholecalciferol, B vitamins, iron preparations and omega-3 polyunsaturated fatty acids with positive dynamics. The clinic and pathogenesis of Graves' disease and the effect of vitamin D on the pathogenetic pathways of autoimmune diseases are discussed. Key words: autoimmune diseases, Graves–Bazedov disease, vitamin D, diffuse toxic goiter, calcidiol, calcitriol, cholecalciferol
Analysis of Musytarak Al-Lafdzi the Word “Kutiba” in the Qur'an: A Study of Semantic Analysis
Authors: Dinia Hima Roiku , Nikmah Unzilatun , Ila Ifawati Nur
Published: March 2024

The diversity of meanings in Musytarak lands in the Al-Qur'an is a challenge in the translation process, which causes ambiguity and the potential for multiple understandings if it needs to be translated or understood correctly. An example is lafadz, "kutiba," which has various meanings in the Qur'an that are very different from the original. This research aims to identify the meaning of the mustard lafdzi phenomenon, especially the lafadz “khutba" in the Al-Qur'an. This research is descriptive and qualitative using the literature review method. The data in this research comes from the Al-Qur'an, translations from several sources, and scientific works in relevant journals or books. The data was then analyzed descriptively to conclude a brief description. This research shows that Lafadz khutba is a lafa lafdzi repeated 11 times in the Koran and has several meanings. Lafadz kutiba means furidha (Required) found in Surah Al-Baqarah verses 178,180, 183, 216, 246, and An-Nisa' verse 77. Lafadz Kutiba means ju'ila (Made), found in Surah Ali Imron verse 154 and At-Taubah verses 120-121. The lafadz kutiba, meaning qudhiya (Determined or determined), is in Surah An-Nisa's verse 127 and Al-Hajj's verse 4. Thus, these results contribute to understanding the complexity of the meaning of "Kutiba" in the Al-Qur'an, emphasizing the importance of context in interpretation and translation to avoid misunderstandings.
Epistemologi Pemikiran Gabriel Said Reynolds tentang Konsep Homili Al-Qur’an
Authors: Haiva Satriana Zahrah
Published: March 2024

Studi ini mencoba melihat epistemologi pemikiran Reynolds yang menggagas konsep homili untuk membaca (memahami) Al-Qur’an. Reynolds melakukan formulasi baru dalam melihat pola keterhubungan antar teks dan mencoba mematahkan argumentasi yang menganggap Al-Qur’an sebagai teks imitasi dari tradisi Yahudi dan Kristen. Adapun tujuan dari penelitian ini ialah untuk mendeskripsikan konsep homili yang digagas Reynolds, kemudian meninjau epistemologi pemikirannya dan menjelaskan implikasi konsep tersebut. Penelitian ini merupakan studi kualitatif berupa studi kepustakaan (library research) dengan menggunakan buku the Qur’an and its Biblical Subtext sebagai sumber data primer dan  menggunakan pendekatan hermeneutika teoritis sebagai pisau analisis dalam mengkaji buku tersebut. Hasil penelitian ini menunjukkan bahwa Al-Qur’an dengan teks-teks pra-Quranic  memiliki genre  sastra yang berbeda, di sisi lain Al-Qur’an memiliki sifat homili dalam mengembangkan nilai-nilai religiusnya. Konsep homili ini membawa konsekuensi metodologis untuk membaca atau menafsirkan Al-Qur’an dengan teks-teks sebelumnya yiatu Alkitab apokrifa dan karya eksegesis Yahudi dan Kristen. Secara metodologis, Reynolds menggunakan teori aludding dan menggunakan pendekatan sastra. Konsep homili berimplikasi pada penilaian terhadap Alkitab agar mencurigainya secara buta dan penggunaan Alkitab sebagai sumber atau rujukan dapat menjadi alternatif dalam memahami Al-Qur’an.
The Sunlight in the Qur'an and Its Use in Health According to Tantawi Jauhari
Authors: Mujahidin Afif Askar
Published: March 2024

وجدنا بأن الكثير من البحوث حول القرآن من حيث جوانب العلم. بدأ هذا البحث منذ بدء التطور التفسير الذي له لون علمي. من الأمور التي تمت بحثها في هذه القضية، هو البحث الشمس في القرآن. والشمس هي مصدر للطافة. ولكن عندما فتشنا هذا البحث أي "الشمس في القرآن بدراسة العلمية" غالبا يتعلق حول الأمور الكونية وليس بكثير في هذا البحث الذي يتعلق بالدريسة العلمية مع أن نفس الإنسان أقرب من الكون في الآفاك. من ناحية أخرى، فإن اهتمام الإنسان بأهمية الشمس لنفسه غير موجود أيضا. بناء على المشكلة المذكورة أعلاه ، يقدم الباحث أفكار  طنطاوي  جوهري فيما يتعلق بالشمس في القرآن والتي ينظر إليها من منظور العلم الذي يركز على جوانب النفس أو في هذه الحالة الأشياء المتعلقة بالصحة. يستخدم هذا البحث منهجا وصفيا في التحليل مع المنهج المستخدم هو الإعجاز القرآن. ثم من حيث جمع البيانات يقوم الباحث بجمع البيانات المستمدة من الكتب الأولية والمجلات والمقالات، لذلك فإن هذا البحث هو بحث مكتبي (Library Research) لشرح وبحث في مفاهيم الشمس في القرآن وعلاقتها بالصحة من حيث تفسير طنطاوي  جوهري وزغلول راغب النجار .بعد تحليل هذه الدراسة من كتب التفسير العلمي ، أوضحت نتائج هذه الدراسة أن الله خلق الشمس كما شرحه في القرآن لفوائد كثيرة للمخلوقات جميعا بالإضافة إلى فوائد الكونية وهناك أيضا فوائد صحية للناس ، انطلاقا مما شرح طنطاوي ‏ جوهري سورة يونس الآية 5 ، يستنتج المفسر أن ضوء الشمس له فوائد كثيرة للإنسان مثل القدرة على زيادة القوة والصحية، والقضاء على فقد الدم، وتحفيظ النساء الحوامل وزيادة مناعة الجسم. بالإضافة إلى ذلك، الشمس نفسها هي منبه نمو هرمون الميلاتونين الذي يتم إنتاجه في الغدة الصنوبرية. Pineal gland—
INVESTIGATION OF SUBSURFACE GROUNDWATER USING THE VES METHOD AROUND DENDAM LAKE, BENGKULU CITY, INDONESIA
Authors: Maghribi Faritz Bagda , Refrizon Refrizon , Suhendra Suhendra , Fadli Darmawan Ikhlas , Halauddin  , Idris Beni Syakban , Johan Henny , Putriani Eli
Published: March 2024

Concerns have been raised over the availability of water in the Dendam Lake neighborhood of Bengkulu City and the areas surrounding it. The location is characterized by a number of unsuccessful water wells. These issues are the direct and indirect results of the geological formations that are present in the region, specifically Aluvium (which consists of boulders, clasts, sand, silt, mud, and clay). A MAE X-612 EM resistivity meter was utilized in order to get a total of twenty Vertical Electric Sounding (VES) measurement points. Using the software programs Progress and Surfer, the data that was gathered was plotted on a two-log graph. The geoelectric layer and layer parameter maps that were made were prepared with the use of quantitative and qualitative interpretations. It was determined that there were between three and five geoelectric layers. It has been demonstrated that the resistivity of the subsurface shallow groundwater zone ranges from 10 to 20 Ωm at a depth of 4 to 15 meters. According to the findings of this research project, employing the VES geo-electrical exploration approach is likely capable of effectively outlining the subsurface and shallow groundwater. In addition, there is no information available regarding the precise depth of the groundwater table in the region. On the other hand, the underground groundwater at this location has a depth that is shallower than the norm.
AIRCRAFT TRAFFIC NOISE ANALYSIS AT KUALANAMU INTERNATIONAL AIRPORT MEDAN
Authors: Indrayani Indrayani , Rajagukguk Juniastel , Rahayu Tri , Siregar Rizky , Rajagukguk Juniastel , Dirza Risvan
Published: March 2024

This study was conducted to analyze and evaluate the noise generated by aircraft traffic at Kualanamu airport. Data collection was carried out by conducting a survey directly in the field by asking airport officials about the flight frequency at Kualanamu airport and measuring ground handling noise with a sound level meter. Furthermore, the data obtained were analyzed using Excel software. From the results of data processing, it is known what variables most affect ground handling noise at Kualanamu airport. Noise measurements were taken by PT. Angkasa Pura II (Persero) in an open area at Kualanamu airport, the noise that occurs is below the specified quality standard value, which is <80 dB based on the Minister of Transportation Decree No. 17 of 2005 (Sultan Syarif Kasim International Airport, while for Kualanamu International Airport there has not been a Ministry of Transportation Decree. Because both airports are international class and are located in the coastal area of Sumatra Island, it can be assumed that they have the same noise quality standards). Furthermore, noise measurements were taken by PT. Angkasa Pura II (Persero) in the domestic and international waiting room area that the noise that occurs is above the specified quality standard value, namely (45-55) dB Zone B, according to the regulation of the minister of health 718 of 1987.
Pengaruh Inflasi dan Nilai Tukar terhadap Ekspor Produk Halal Indonesia Periode 2016-2020
Authors: Sovia Zahrianti Erika , Wirawan Fadly
Published: March 2024

The potential for halal products in the global market is currently experiencing rapid development, marked by an increase in demand every year. However, as the largest Muslim country is still in the spotlight because of the low export of halal products and even far behind non-Muslim countries. It may be influenced by inflation and exchange rate fluctuations in Indonesia. This study uses time-series data for the period January 2016-December 2020 with the Auto-Regressive Distributed Lag Models (ARDL) analysis method. The results show that (1) Inflation has no significant effect on exports of halal products in the short and long term. (2) The exchange rate has a negative and significantly effect on exports of halal products in the short term, but has no significant effect in the long term. (3) Inflation and exchange rates simultaneously have a significant effect on the export of halal products with a contribution of 32.06%.
Progresivitas Hukum Pembebanan Nafkah Pasca Cerai Gugat Di Pengadilan Agama Magetan
Authors: Wafiroh Siti , Purnomo Agus , Maulidia Rohmah
Published: March 2024

Based on the Magetan Religious Court Decision Number 716/Pdt.G/2021/PA. Mgt, whohanded down the verdict, said one of the reasons was to impose a living on the husband. Thedecision is contrary to Article 149 of KHI, which states that the wife who filed for divorcedoes not get a living because the wife is considered nusuz. This research was conducted witha qualitative approach where the data source was taken from direct interviews with theMagetan Religious Court Judge and the Magetan Religious Court decision. The researchresults were described descriptively using words. The results of this study are the basis forconsideration in deciding case Number 716/Pdt.G/2021/PA. Mgt based on the SupremeCourt Circular Number 3 of 2018, the wife in a divorce case can be given mut'ah and iddahas long as it is not proven nusuz and in its proof that it is not proven that the Plaintiff hascommitted nusuz to the Defendant so that the Panel of Judges grants the Plaintiff's claimand in determining the amount of income that the amount of mut'ah is adjusted to theetiquette and ability of the husband so that it does not occur the judgment not executed wasdue to the incompetence of the Defendant. The panel of judges adheres to the progressive legalparadigm and has the courage not to want to mouthpiece the law. This reflects thecharacteristics of progressive law, namely the Judge's decision to follow the situation andcondition of thePlaintiff.