bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficacy and Safety of a Tubeless AID System Compared With Pump Therapy With CGM in the Treatment of Type 1 Diabetes in Adults with Suboptimal Glycemia: A Randomized, Parallel-Group Clinical Trial
Authors: Renard Eric , S. Weinstock Ruth , Aleppo Grazia , W. Bode Bruce , A. Brown Sue , Castorino Kristin , B. Hirsch Irl , S. Kipnes Mark , M. Laffel Lori , A. Lal Rayhan , Penfornis Alfred , Riveline Jean-Pierre , N. Shah Viral , Thivolet Charles , T. Ly Trang
Published: October 2024

Objective: To examine the efficacy and safety of the tubeless Omnipod® 5 Automated Insulin Delivery (AID) System compared with pump therapy with a continuous glucose monitor (CGM) in adults with type 1 diabetes with suboptimal glycemic outcomes. Research Design and Methods: In this 13-week multicenter, parallel-group, randomized controlled trial in the United States and France, adults aged 18-70 years with type 1 diabetes and HbA1c 7-11% (53-97mmol/mol) were randomly assigned (2:1) to intervention (tubeless AID) or control (pump therapy with CGM) following a two-week standard therapy period. The primary outcome was a treatment group comparison of time in range (TIR; 70-180mg/dL) during the trial period. Results: A total of 194 participants were randomized; 132 to intervention and 62 to control. TIR during the trial was (mean difference (95% CI)) 17.5% (14.0%, 21.1%) (4.2 hours per day) higher in the intervention compared with the control arm (P<0.0001). The intervention arm had a greater reduction in HbA1c from baseline compared with control (mean±SD) (-1.24±0.75% [-13.6±8.2mmol/mol] vs. -0.68±0.93% [-7.4±10.2mmol/mol], respectively) (P<0.0001), accompanied by significantly lower time <70mg/dL (1.18±0.86% vs. 1.75±1.68%, P=0·005) and >180mg/dL (37.6±11.4% vs. 54.5±15.4%, P<0.0001). All primary and secondary outcomes were met. No instances of diabetes-related ketoacidosis or severe hypoglycemia occurred in the intervention arm. Conclusions: Use of the tubeless AID system led to improved glycemic outcomes compared with pump therapy with CGM among adults with type 1 diabetes, underscoring the clinical benefit of AID and bolstering recommendations to establish AID systems as preferred therapy for this population.
Early mobilization in patients with aneurysmal subarachnoid haemorrhage may im-prove functional status and reduce cerebral vasospasm rate: a systematic review with meta-analysis
Authors: Foudhaili Adéla , Leclere Brice , Martinache Florence , Chauvin Anthony , Vitiello Damien , Chousterman Benjamin
Published: October 2024

Objective: The primary aim of this study was to evaluate the safety and efficacy of early mobilization in patients with aneurysmal subarachnoid haemorrhage.
Design: Systematic review with meta-analysis of randomized controlled studies and observational studies.
Patients: Patients with aneurysmal subarachnoid haemorrhage.
Methods: PubMed, Embase, CINAHL, Web of Science, Pedro, and the Cochrane Library databases were searched. A systematic review and meta-analysis were performed. Screening and data extraction were performed by 2 independent reviewers.
Results: Sixteen studies involving 1,757 patients were included. Meta-analysis of the data estimated that early mobilization improved mRS score at discharge (mean difference –1.39, 95% CI –2.51 to –0.28, I2 = 86%) and at 3 months (mean difference –1.10, 95% CI –1.54 to –0.66, I2 = 7%). Early mobilization was associated with a reduction in cerebral vasospasm rate, both radiological (OR 0.66, 95% CI 0.45 to 0.96, I2 = 7%) and clinical (OR 0.44, 95% CI 0.27 to 0.72, I2 = 8%); 6% of mobilization sessions involved adverse events, mostly haemodynamic changes.
Conclusion: This review found moderate-quality evidence supporting the safety and effectiveness of early mobilization in patients with SAH. Further randomized controlled trials are needed to identify the appropriate mobilization strategy and confirm these results.
Bacterial Adhesion and In Situ Biodegradation of Preheated Resin Composite Used as a Luting Agent for Indirect Restorations
Authors: Bezerra ALCA , Gonçalves GGA , Alves LC , Stamfor TCM , De Brito OFF , Monteiro GQdeM
Published: October 2024

Objective:

To evaluate surface roughness and bacterial adhesion after in situ biodegradation of the cementation interface of indirect restorations cemented with preheated resin composite.

Methods and Materials:

Resin composite blocks (Z250XT/3M ESPE) were cemented to bovine enamel (7 × 2.5 × 2 mm) using preheated microhybrid resin composites: (1) Filtek Z100 (3M ESPE) (Z100); (2) Gradia Direct X (GC America) (GDX); and (3) Light-cured resin cement RelyX Veneer (3M ESPE) (RXV) (n=21). The resin composites were preheated on a heating device (HotSet, Technolife) at 69°C for 30 minutes. Disk-shaped specimens (7 × 1.5 mm) were made for biodegradation analysis with the luting agents (n=25). The in situ phase consisted of 20 volunteers’ using an intraoral palatal device for 7 days. Each device had six cylindrical wells for the blocks and the disk-shaped specimens. Biodegradation was evaluated through surface roughness (Ra), scanning electron microscopy (SEM) micromorphological analysis, and colony-forming unit (CFU) count. The film thickness of the luting agents was also measured under stereomicroscopy.

Results:

Increased surface roughness was observed after the cariogenic challenge without differences between the luting agents. Higher variation and surface flaws suggestive of particulate detachment were observed for Z100. No differences were observed in CFU counts.

Conclusions:

All materials underwent surface biodegradation, and the surface roughness of the resin cements was similar to or lower than that of the preheated resin composites. The resin composites’ film thickness was thicker than that of the resin cement. Clinicians should be aware of these factors when choosing the use of preheated resin composite since it can lead to reduced longevity of the cementation interface and, therefore, restorations.
Is It Possible for Single-shade Composites to Mimic the Color, Lightness, Chroma, and Hue of Other Single-shade Composites? An In Vitro Study
Authors: Buldur M , Ayan G
Published: October 2024

Objectives:

This study aimed to assess color matching post-repair using the same or different single-shade composites of three distinct composite resin materials (Omnichroma-OM, ZenChroma-ZC, and Charisma Topaz One-CTO) following aging in coffee solution and distilled water. Evaluation focused on color change parameters (∆E00, ∆L00, ∆C00, and ∆H00).

Methods and Materials:

Specimens were prepared in disk shape with a diameter of 8 mm and a height of 2 mm (n=180). Half of each composite group was immersed in distilled water, while the other half was immersed in coffee solution for 12 days each (n=90). After aging, cylindrical cavities with a diameter of 4 mm and a depth of 1 mm were prepared at the center of the specimens. The cavities were repaired with both themselves and other composite resins (n=10). Color measurements of the specimens were performed using VITA Easyshade 5 (VITA Zahnfabrik, Bad Säckingen, Germany) at the following time points: baseline (T0), after aging (12 days) (T1), immediately after repair (T2), one day after repair (T3), one week after repair (T4), and one month after repair (T5).

Results:

Statistically significant differences were found in the mean ΔE00 measurements among the study groups at all time points for each of the three composite resins (p<0.05). Similarly, statistically significant differences were found in the mean ΔE00 measurements over time for each of the three composite resins in each study group (p<0.05). The baseline measurements of materials repaired with themselves in the distilled water groups and the final measurements of materials repaired with themselves in the coffee groups were found to be within acceptable ∆E00limits. At the end of the study, only CTO repaired with OM showed acceptable color matching with different composites in both coffee and distilled water groups.

Conclusions:

Acceptable color matching was achieved when using the same material for repair in specimens aged in distilled water and coffee. However, variations in matching were observed when different materials were used for repair, indicating the need for ongoing monitoring. Contributions of ΔL00, ΔC00, and ΔH00 values to color differences vary depending on the resins and repair process and change over time.
POLÍTICAS PÚBLICAS E ALIMENTAÇÃO SAUDÁVEL: A RELAÇÃO ENTRE O PNAE E AGRICULTURA FAMILIAR A PARTIR DE UMA REVISÃO SISTEMÁTICA DA LITERATURA
Authors: Vitorino-Santos Daiane Flores , Silva Danielle Wagner , Lustosa Denise Castro , Alves Helionora da Silva , Vieira Thiago Almeida
Published: October 2024

O objetivo deste artigo foi analisar o processo de implementação do Programa Nacional de Alimentação Escolar (Pnae), após a criação da Lei 11.947/2009, e a sua relação com a Agricultura Familiar para a promoção da alimentação saudável dos alunos da rede pública de ensino, por meio de uma revisão sistemática na literatura. Realizou-se buscas de artigos publicados nas bases de dados Scopus e Web of Science, sendo consideradas publicações a partir do ano de 2010. Os resultados demonstram que os trabalhos analisados têm em comum o reconhecimento de que a política pública do Pnae é de fato um passo importante para a Agricultura Familiar, no que diz respeito a promoção de hábitos alimentares saudáveis e do desenvolvimento sustentável, bem como o seu caráter transversal e multidisciplinar, tendo em vista as dimensões da educação, saúde e sustentabilidade ambiental que envolve esta política. É importante que haja o aprimoramento do Programa no intuito de viabializar, de forma eficiênte e eficaz, a sua razão de existir, que é a promoção de hábitos alimentares saudáveis no ambiente escolar, bem como a promoção do diálogo entre os diferentes tipos de saberes, para uma melhor implementação e gestão.
POLÍTICAS DE INCLUSÃO OU A INFÂNCIA DISCIPLINARIZADA? POSSIBILIDADES DE INSURGÊNCIAS EPISTEMOLÓGICAS
Authors: Silva Adriana Duarte de Souza Carvalho da , Valentim Rayane Emanuelle de Oliveira , Carvalho Enderson Rodrigues de , Cavalcante Patrícia Cristina , Martins Roberta Alice Januzzi
Published: October 2024

As políticas de inclusão educacional no Brasil avançam enquanto possibilidades de ingresso de corpos tipicamente subalternizados na escola, garantindo, assim, o direito à educação. Contudo, ao adentrar a escola, esses corpos são moldados para se adaptarem às demandas escolares e são, dessa forma, subalternizados a um discurso da disciplina. Diante desse contexto, esse trabalho tem como objetivo discutir o caráter das políticas de inclusão no Brasil a partir das abordagens de Foucault e Han. Essa pesquisa se organizará em uma perspectiva de relato de experiência, por meio da qual uma das autoras dessa investigação vai narrar sua trajetória como psicopedagoga, analisando como a demanda por “corpos escolarizados” está presente nas políticas de inclusão brasileiras, que não rompem efetivamente com o discurso psiquiátrico Ao final, relataremos que em uma sociedade da disciplina e do desempenho, as políticas de inclusão são tomadas pela lógica biomédica e de adestramento de corpos.
Important Practical Conditions for Getting the High-Quality Foam Concretes
Authors: Morgun L. V.
Published: October 2024

Introduction. The most important reasons justifying the relevance of the research on the practical methods of reducing the consumption of materials in construction industry have been distinguished. The priorities of the Russian Federation referring to the foam concrete technology have been outlined. The level of reliability of the Internet resources describing properties of the dispersedly reinforced foam concretes has been briefly evaluated. The aim of the study is to establish the relationships between the individual properties of fiber, its quantity to the mass of cement ratio, and the most important operational properties of foam concrete manufactured using a single-stage technology.

Materials and methods. The types and properties of raw materials used in the experimental research, the methods for controlling the properties of mixes and hardened foam concretes have been defined.

Results. The relationship between the speed of phase transition of the viscoplastic properties of the foam concrete mixes into the elastic ones and the possibility of getting a high-quality structure of the hardened foam concrete have been briefly theoretically justified. The physical reasons influencing the direction and speed of forming the raw material dispersed particle clusters in the structure of the interpore partitions of foam concrete mixes have been revealed, which are the important factors to be considered in practice to get the high-strength foam concretes. Depending on the fiber concentration in the concrete mixture composition, the specifics of the fiber physical nature influence on the speed of phase transition from viscoplastic to elastic state have been established. It has been proved that the synergetic effect of dispersed reinforcement is achieved when fiber concentration is enough to provide the significant acceleration of the phase transition. New experimental data on the influence of the individual properties of fiber on the rheological and physico-mechanical properties of D500 foam concrete has been obtained.

Discussion and Conclusion. The scientific explanation of the reasons for emergence of the electret effect on the surface of synthetic fiber has been given. It has been revealed that the discovered effect is induced by the specifics of the foam concrete mixture preparation using a single-stage technology. The most important practical conditions due to be met to get the high-strength foam concrete have been determined.
On the Numerical Solution of Linear and Non-Linear Dirichlet Boundary Value Problems of Ordinary Differential Equations: The Shooting Method
Authors: Odongo Benard Audi , Opiyo Richard Otieno , Owego Dancun Okeso , Onyango Thomas Mboya
Published: October 2024

In this article, a numerical technique called shooting which entails the solution of initial value problems with the single-step fourth-order RungeKutta method together with the iterative root finding secant method is formulated for use on both linear and non-linear boundary value problems of ordinary differential equations with Dirichlet boundary conditions. Two examples are illustrated. One, the solution of the linear case with its analytic counterpart is compared, and two, the non-linear case. Graphical outputs of the solutions from two MATHEMATICA codes are presented.
THE DYNAMICS BETWEEN VULNERABILITY AND FAITH IN MARK 5:25-34: INSIGHTS FROM IGNATIAN PEDAGOGY
Authors: Dirgaprimawan Bernadus , Ariyanto Yohanes Ferry
Published: October 2024

This article employs an exegetical approach to examine the story of a woman afflicted with a 12-year hemorrhage who finds healing through her faith in Jesus. The objective is to identify the multifaceted vulnerabilities she confronts, encompassing physical, emotional, cognitive, and social dimensions. Despite societal marginalization, her story challenges societal norms and religious laws, emphasizing her deep faith and the transformative impact of encountering Jesus. This study, informed by Ignatian pedagogy, focuses on the holistic understanding of human nature and on the character development of the woman in that story. The analysis illuminates the woman's profound physical affliction, emotional distress, cognitive challenges, and social marginalization. Furthermore, it investigates how her unwavering faith in Jesus transcends societal norms, leading to personal healing and human maturity. The results highlight how faith and compassion can bring about significant change, showing how Ignatian spirituality offers valuable insights into addressing vulnerability and encouraging empathy for those facing challenges in life.
PERAN INTEGRATIF PENDIDIKAN JESUIT DALAM FORMASI KEPEMIMPINAN IGNATIAN
Authors: Witono Odemus Bei
Published: October 2024

This article explores through a qualitative approach the guiding principles and educational philosophy of Jesuit institutions, focusing on their holistic approach to personal and intellectual development. Key elements include the integration of faith and reason, the commitment to social justice, and the formation of students as conscientious and competent leaders. Central to this philosophy are the concepts of finding God in all things, the transience and immanence of God, and the dedication to the greater glory of God (AMDG) and the principle of "Magis." Keywords: Jesuit education, school, character development, faith and reason, social justice, leadership, Magis, Cura Personalis, reflective practices.
Sustainability of Hospital Accreditation Programs in Low and Middle-Income Countries: Lessons learned from Sri Lanka
Authors: Dharmagunawardene Dilantha , Avery Mark , Bowman Paula , Greenfield David , Hinchcliff Reece
Published: October 2024

Objective: Many hospital accreditation programs developed for or implemented in Low and Middle-Income Countries (LMICs), including Sri Lanka, have been discontinued due to multiple factors. This study was conducted to elicit and analyse factors influencing the Sri Lankan hospital accreditation program that was initiated in 2015.
Design: This case study employed document reviews and 18 key informant interviews with stakeholders involved in Sri Lanka's accreditation program. Collected data were thematically analysed.
Setting: Sri Lankan healthcare system.
Main outcome measures: Data extraction was guided by the constructs of the ACES-GLEAM Framework, which was developed based on the results of a scoping review.
Results: Barriers identified were frequent changes in the leadership and strategic plans, lack of awareness and competencies on accreditation among local stakeholders, and non-alignment of accreditation standards with the local health system context hampered by resource and infrastructure constraints. Enablers for program development commonly raised were the commitment of stakeholders, the availability of institutional structures for quality assurance, donor funding from the World Bank, and technical expertise and surveyor training by the Australian Council on Healthcare Standards International.
Conclusions: The study identified that multiple factors contributed to the poor sustainability of the Sri Lankan accreditation program. These findings can be useful reflections and guidelines for the accreditation stakeholders to establish sustainable and effective programs in LMICs.
On Fω-covering subgroups of finite groups
Authors: Sorokina M.M. , Novikova D.G
Published: October 2024

In this paper, we study Fω-covering subgroups in the case when F coincides with the direct product X×H of a non-empty hereditary class of groups X closed with respect to homomorphic images and a hereditary ω-local formation of groups H. Only finite groups are considered. A subgroup H of a group G belonging to the class of groups F is called an Fω-covering subgroup of a group G, where ω is a non-empty set of primes, if from the fact that H is contained in the subgroup U of G and U/V ∈F , where V is a normal ω -subgroup of U, it follows that U=HV. Conditions under which for the class F = X×H an ω-solvable group G has at least one F ω-covering subgroup are established.
Coherence of religious conversion with the problems of the aspect of Islamic national identity
Authors: Sinyakov O.V.
Published: October 2024

In modern conditions, the structure of Muslim identity under the influence of religious conversion undergoes weakening, loses its integrity, and undergoes homogenization. Moreover, as a result of the transition from one religion to another, there is a mutation, transformation and modification of the identity of the convertit's personality, which ultimately can lead to a change in the identity of society. The analysis of the identity of Muslims living in foreign countries, the post-Soviet space and Kazakhstan is carried out. The author suggests a number of measures to prevent adherents from falling into destructive pseudo-religious organizations.
Possibility and actuality in the structure of objective reality
Authors: Loskutov Yu. V.
Published: October 2024

On the material of general philosophy and social philosophy it is substantiated that possibility lies at the basis of actuality in the structure of objective reality. The general philosophical argument in defense of this thesis is the paradox of the shadow system. The key role of abilities and needs in the structure of essential powers of a man serves as a socio-philosophical argument.
Nonequilibrium critical behavior of weakly diluted three-dimensional anisotropic Heisenberg model
Authors: Prudnikov V.V. , Prudnikov P.V. , Khitrintseva V.V.
Published: October 2024

The results of a Monte Carlo study of weakly structural disorder influence onnonequilibrium critical behavior of three-dimensional anisotropic Heisenberg models with spin concentration p = 0.9 are presented with its evolution from high temperature initial state. It is shown that presence of even weakly disorder changes characteristics of nonequilibrium critical behavior of anisotropic model with easy axis anisotropy type in comparison with both pure anisotropic and isotropic Heisenberg models.
Naturalness in the philosophy of Jean baudrilland
Authors: Dobronravov K.O.
Published: October 2024

The article presents an analysis of the concept of “natural” in the philosophy of J. Baudrillard, which is of key importance for understanding his heritage. Concepts close in a circle that are found in the author's work, such as “naturalization”, “naturalness”, “naturalness”, “naturalness”, are analyzed. Based on the study of works, we single out the forms of its natural existence in modern culture: as a simulacrum “aturalness” at the level of consumption, as a natural reference of a sign, as a false scientific connotation. It is also naturally the key to reflecting on the foundations of the evolution of simulacra in European culture: a fake, a robot, a code. The conclusion is made about the importance of the process of naturalization of functions as phenomena of modern culture, blurring between naturalness and unnaturalness.
Higher education in Russia: catch-up or forward-looking of the development?
Authors: Puzikov V.G.
Published: October 2024

The article claims that as a result of ineffective reform, the quality of higher education is reduced. The main reason for the occurrence of such a situation is the old paradigm of the catchy development of the education system of Russia. The necessity of replacing the old paradigm to the new one is justified. The strategy of the new paradigm of the advanced development of education has two basic source principles - continuity and integitivity.
Language change and media literacy: perspectives on Russian as a foreign language teaching in the digital age
Authors: Bacher S. , Howanitz G. , Stadler W.
Published: October 2024

An analysis of recent publications offers either a bleak or a bright perspective on Russian as a foreign language teaching: While some authors paint a dark future changing the face of humans into an artificial synthesis with a robot, others indulge in mobile technologies of language learning projects, transforming the analogue classroom into a digital space with virtual learning tools where native-speaker teachers work with foreign language learners from generation Z. There is no doubt that Russian language classrooms are adapting to the use of the Internet, social media and e-textbooks. In view of the above, an important question is how to support (future) teachers and learners in the digitalisation process. A basic prerequisite for the purposeful use of new media in the classroom is media literacy for both teachers and students. The aim of our research is how to teach Russian language learners media literacy, linguistic behaviour, and how to motivate them in a new dynamic era where English dominates global communication. In this context, we refer to the achievements of Internet research. Subject sciences and language pedagogy can work together to point out the overlapping processes of a globalised Internet, on the one hand, and a Russian-speaking Runet, on the other hand - processes which emphasise the importance of the knowledge of the Russian language. The results of our study demonstrate how the cultural characteristics of the Runet can help teachers to connect to the learners' experience and to explain media-didactic issues at the same time (online counterpublics, "fake news", etc.).
Sports podcasts in the aspect of dialogical communication
Authors: Malysheva E.G. , Rogaleva O.S.
Published: October 2024

The relevance of studying the communicative and pragmatic characteristics of podcast is determined by the ever-increasing popularity of this media format. The object of research in this article is a podcast - a media format whose communicative dominant is an orientation towards dialogic interaction both between the addressees of the mass media discourse - journalists, presenters, and between the addresser and the addressee. The purpose of the article was to identify the thematic, genre and communicative-pragmatic specificity of sports podcasts on the example of the podcast about figure skating "Chistyi khvost" ("Clean Tail"; Sports.ru). The degree of study of the stated topic is explicated in the review of scientific literature, the theoretical research of researchers is supplemented by the authors: the systematization of existing podcast typologies is proposed, new grounds for classifying the format are identified, and the definition of the concept of "podcast" is given. The use of an interconnected set of methods and techniques of media linguistics and media stylistics (content analysis, thematic, genre, contextual, linguostylistic, pragmatic analysis of media texts) made it possible to identify the communicative and pragmatic features of a sports podcast, the communicative types of its presenters, the means and methods of dialogization. It has been established that the sports podcast "Chistyi khvost" is a modification of the genre of radio discussion with elements of a phatic radio conversation, colloquial polylogue. It is concluded that genre hybridization makes it possible to implement the intentions of informing, influencing and entertaining in a podcast. Genre diffusion leads to significant changes in the communicative and pragmatic characteristics of the media text. The discursive personalities of the podcast hosts are characterized as communicative types of sports commentators - "jokers" with elements of "analysts" and "fans". Their discussion on the podcast "Chistyi khvost" has a relaxed and natural conversation that meets the needs of the target audience - the sports community of figure skating fans.
Media framing and media detectives construction: a case About corruption
Authors: Radina N.K. , Iakupova K.R.
Published: October 2024

This study analyzes how media narratives about investigating corruption crimes are created. It is assumed that such a media narrative is built according to the rules of a detective story in fiction. The theoretical framework of the research is frame analysis in media research. Materials for the research are the texts of Russian media sources that participated in covering the story of the ex-minister Alexey Ulyukaev corruption crime (2016-2018). The results show that contemporary media sources use frames typical of literary works to represent events to the audience (detective frame for this case). Using media framing, the topic of corruption crimes in the media is transformed into a detective story and turns into entertainment. The study proposes to consider the modern media detective story as a narrative distributed among several media. The study develops the idea of combining news and entertainment in the media discourse in order to manage the opinions of readers (distract them from political problems).
REVIEW ON: Klyukanov, I.E. (2022), Communication. A House Seen from Everywhere, Foreword by J.D. Peters, New York, Berghahn Books, 246 p., 8 ill. DOI: 10.3167/9781800735248
Authors: Protassova E.Yu.
Published: October 2024

The article presents a review of the book by Igor Engelevich Klyukanov, specialist in intercultural communication. The reviewer notes that the author gives in his monograph a qualitative overview of latest works in the field under consideration and illuminates them in line with the chosen theory.
ConvAtt Network: A Low Parameter Approach For Sign Language Recognition
Authors: Rios Gaston Gustavo , Dal Bianco Pedro , Ronchetti Franco , Quiroga Facundo , Ponte Ahón Santiago , Stanchi Oscar , Hasperué Waldo
Published: October 2024

Despite recent advances in Large Language Models in text processing, Sign Language Recognition (SLR) remains an unresolved task. This is, in part, due to limitations in the available data. In this paper, we investigate combining 1D convolutions with transformer layers to capture local features and global interactions in a low-parameter SLR model. We experimented using multiple data augmentation and regularization techniques to categorize signs of the French Belgian Sign Language. We achieved a top-1 accuracy of 42.7% and a top-10 accuracy of 81.9% in 600 different signs. This model is competitive with the current state of the art while using a significantly lower number of parameters.
An Agent-Based "Virtual Clinical Trial" for the Analysis and Evaluation of COPD Patients Cohorts Behavior
Authors: Hallaj Asghar Mohsen , Wong Alvaro , Epelde Francisco , Taboada Manel , Rexachs Dolores , Luque Emilio
Published: October 2024

Chronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory condition characterized by inflammation and narrowing of the airways, leading to symptoms such as shortness of breath, coughing, and chest tightness. Treatment typically involves lifestyle adjustments, medication, and pulmonary rehabilitation to improve lung function and quality of life. This study presents a model examining COPD patient behavior within cohort-based strategies, focusing on how environmental factors impact vital signs across the entire cohort. We developed a comprehensive virtual clinical trial model that encompasses study protocol design, participant recruitment, virtual data collection, outcome analysis, and conclusions. This includes remote symptom monitoring, virtual healthcare consultations, treatment adherence assessments, and research data collection. Additionally, we explore the influence of external variables such as environmental conditions, comorbidities, and lifestyle factors on chronic disease symptoms and disease stability. We used an Agent-Based Model(ABM) to incorporate these factors to assess COPD progression and treatment efficacy. Individual agents represent COPD patients, each characterized by attributes such as age, smoking history, lung function, comorbidities, and treatment plans.
SOSYAL BİLGİLER ÖĞRETMENLERİNİN VATANDAŞLIK ANLATISI: VATANDAŞLIK EĞİTİMİ VE İNŞASI
Authors: Akarsu Ali Haydar
Published: October 2024

Bu araştırma, Türkiye’deki devlet okullarında nasıl bir vatandaşlık eğitimi kavramsallaştırmasının hâkim olduğunu, vatandaşlığın inşasında kritik aktörler olan sosyal bilgiler öğretmenlerinin perspektifleri üzerinden keşfetmeyi amaçlamaktadır. Bu kapsamda, Türkiye genelinde farklı sosyo-ekonomik statülerden kamu ortaokullarında görev yapan en az beş yıllık mesleki deneyimine sahip altı sosyal bilgiler öğretmeniyle yarı-yapılandırılmış görüşmeler gerçekleştirilmiştir. Araştırma nitel türde olup ‘anlatı sorgulaması’ deseni kullanılmıştır. Veriler yarı yapılandırılmış fenomenolojik görüşmelerle toplanmıştır. Öğretmen anlatıları ‘geleneksel vatandaşlık anlatısı’ ve ‘demokratik vatandaşlık anlatısı’ olmak üzere iki ana tema etrafında şekillenmiştir. Geleneksel anlatıda öğretmenler iyi vatandaşı, kolektif bütünün yararı ve iyiliği bağlamında işlevsel olan duygusal kişiler olarak tanımlamışlardır. Bu anlatıya göre, ülkeye, millete ve devlete bağlılık gösteren bireyler iyi vatandaşlar olarak kabul edilmektedir. Karşıt bir anlatı olarak ortaya çıkan demokratik vatandaşlık anlatısı ise; fikir özgürlüğü, kültürel çeşitlilik ve katılım gibi temalar etrafında inşa edilmiştir. Anlatılar, öğretmenlerin vatandaşlık eğitimi anlayışlarında, öğrencilerin haklarından ziyade sorumluluklarını vurgulama eğiliminde olduklarını ve milli değerlerin öğretilmesine önem verdiklerini göstermektedir. Bulgular, vatandaşlık eğitimi anlatılarında öğretmelerin, öğrencilerin toplumun sorunsuz bir parçası olarak yaşama katılmaları için kurallara uymaları ve otoriteye saygı göstermelerinin önemli derecede kabul gördüğünü göstermektedir. Daha çok topluma uyuma odaklanan öğretmen anlatılarında, öğrencilerin çeşitlilik ve farklılıklarının çok fazla dikkate alınmadığı görülmektedir.
Examining Parents' Opinions on Safe School
Authors: Kaya Deniz , Balyer Aydın
Published: October 2024

The aim of this study is to examine the views of parents on safe schools and to develop solutions to the problems encountered in a safe school environment based on these views. The research was conducted with phenomenology design, one of the qualitative research methods. The study group of the research consists of 16 parents selected by criterion sampling and maximum sampling method. The research was carried out with volunteer parents who have at least one student in primary school, secondary school, high school age, high school, bachelor's or master's degree graduates in Fatih district of Istanbul province. The data of the study were collected by semi-structured interview technique and analysed with descriptive analysis method. According to the results obtained, parents' views on safe school were categorised under 6 themes. These themes are safe school ecosystem, social relations and educational safety, health and safety balance in education, resources and implementations for safety and governance, communication and solidarity, safe behaviour and moral values. As a result, it has been determined that parents' views on safe school environment are mainly gathered around physiological and psychological safety for students and school climate based on mutual trust of stakeholders. Based on these results, it is recommended that policy makers and implementers in education should prioritise measures to ensure school safety.
Recent data of the biology of the twaite shad, Alosa fallax returning for spawning to the Szczecin Lagoon (southern Baltic Sea)
Authors: Więcaszek Beata , Czerniejewski Przemysław , Dąbrowski Jarosław , Korzelecka Agata , Formicki Krzysztof , Tański Adam
Published: October 2024

In 2022–2023 specimens of A. fallax are recorded for the first time in approximately 17 years in Szczecin Lagoon. We collected 11 specimens of juveniles, 9 premature and mature females, and 9 premature and mature males (20.3–40.7 cm of total length, aged from 1+ to 4+). The 2+ aged fish was slightly dominated (34.5% of the whole sample). Females in the Szczecin Lagoon were ready to spawn in the age of 3+ and 4+ years, while males partly in 2+, and in the age of 3+ and 4+. Fulton’s condition factor of this fish was 0.93±0.14 and Clark’s 0.78±0.14. Analysis of correlations between the total length and individual weight of fish revealed that the growth of A. fallax was allometric (b < 3.0). The range of gonadosomatic index (GSI) was 0.12–26.59%, while the mean of the absolute and relative fecundity was 58,756 eggs per female and 139,650 eggs per kilogram of body weight. The obtained results indicate the occurrence of an anadromous population of Alosa fallax in the studied water areas. However, there is still a need to obtain detailed information on the population status and the biology of A. fallax in these areas in order to designate special conservation areas (SACs) for their protection, especially taking into account spawning habitats.
Silage harvesting for small farms by using vacuum sealing in flexible polymer containers on a converted trailer
Authors: Khazimov Kanat , Zhumagaliyev Yelaman , Khazimov Zhanat , Khazimov Marat
Published: October 2024

The article presents an analysis of milk production in Kazakhstan and identifies the reason for its low level, which is due to deficient feed, especially in small farms and in the private sector. The difficulty of saving the limited silage volume is due to the lack of preparation technology for preventing spoilage. The objective of this work is to complete the necessary equipment of a mobile tractor-trailer to reduce the specific energy consumption when preparing silage in flexible containers using a vacuum seal to increase the productivity of dairy cattle farming in smallholder and the private sector of the Republic. The basic rational parameters for sealing the silage by vacuum in the field on a mobile tractor-trailer for ease of transport and storage are obtained: silage weight in a flexible container – 769.6 kg, geometric dimensions of the sealed container by height (0.90 m), width (0.85 m) and length (0.85 m). The efficiency of the specific energy consumption of the proposed method for silage preparation is established at 35% compared with the traditional method. The recommended technology of silage preparation in flexible containers will be possible when conventional tractor-trailers are retrofitted with standard portable equipment (internal combustion engine-based (ICE) electric generator, vacuum pump, film welder).
In silico prediction of physicochemical properties and drug-likeness of omega-3 fatty acids
Authors: Staneva Yordanka , Iliev Ivelin , Georgieva Svetlana , Merdjanova Albena
Published: October 2024

Omega-3 fatty acids, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), are recognized for their crucial roles in human health, particularly cardiovascular and cognitive function. In this study, we employed computational methodologies, leveraging the SwissADME platform and ADMETLab 3.0, to predict and cross-validate the physicochemical properties and drug-likeness of these essential fatty acids. SwissADME predictions indicated molecular weights of 278.43 g/mol for ALA, 302.45 g/mol for EPA, and 328.49 g/mol for DHA, with consensus Log Po/w values of 5.09, 5.50, and 5.72 respectively, and varying degrees of water solubility. However, predictions from ADMETLab 3.0 were almost similar: ALA with a molecular weight of 278.22 g/mol, EPA at 302.22 g/mol, and DHA at 328.24 g/mol. Significant discrepancies were observed in lipophilicity, with ADMETLab 3.0 predicting Log Po/w values of 6.461 for ALA, 6.477 for EPA, and 7.006 for DHA, higher than those from SwissADME. Additionally, water solubility predictions from ADMETLab 3.0 showed ALA with a Log S of −5.034, EPA at −4.4, and DHA at −4.638, which differed from SwissADME’s estimates. These differences reflect variations in computational approaches and algorithms. Comparison with literature data revealed general alignment in physicochemical properties, such as water solubility and lipophilicity. Furthermore, assessment of drug-likeness according to Lipinski’s rule demonstrated compliance for all three fatty acids, albeit with variations in other criteria such as Ghose, Veber, Egan, and Muegge rules. These findings underscore the reliability and applicability of computational approaches in elucidating the physicochemical properties and drug-likeness of omega-3 fatty acids, offering valuable insights for pharmaceutical research and therapeutic applications.
Approach regarding the biosafety evaluation of black and red currant pomace extracts using Allium cepa test
Authors: Grosu Luminiţa , Ferenţ Elisa , Nicuţă Daniela , Alexa Irina-Claudia
Published: October 2024

In the present work, biosafety evaluation of black and red currant pomace extracts was conducted using in vivo plant test system, such as Allium cepa, a sustainable method which can provide valuable information on the cytotoxic and genotoxic effect of extracts from natural sources in relation with their phytochemical composition. In this view, different aqueous and hydroethanolic extractions from black and red currant pomaces were carried out. For revealing the differences in the phytochemical profile of the studied extracts, rapid, efficient and easy-to-operate analytical techniques such as colorimetry, UV-Vis spectrometry and electrometry were used. Cytogenetic analysis of pomace extracts was achieved using Allium cepa test by scoring the mitotic index, the limit value of cytotoxicity, the phase index of mitosis and presence of chromosomal aberrations for all samples and comparing to the control (tap water). The results have shown that the cytogenetic response depends both on the type of pomaces and on the experimental extraction conditions. Compared to the control sample (22.58 %), a decrease in mitotic index for each analyzed sample was observed. As well, an increase in the cells with chromosomal aberrations was detected in onion root tips exposed to the tested extracts compared to the control (0.69 %). The lowest value of mitotic index (12.44 %) and the highest value of chromosomal aberrations (1.91 %) were recorded from the root tip cells of onion bulbs exposed to the hydroalcoholic extract obtained from red currants pomace using water/ethanol (60:40 v/v). Even if the mitotic index decreased, the limit value of cytotoxicity was higher than 50 %, level considered as a sublethal condition for the organisms. At the same time, the increase of the frequency of chromosomal aberrations is not so significant, and in correlation with the cytotoxicity limit, it does not indicate a genotoxic effect on onion cells. Following these results, it can be concluded that black and red currant pomace extracts can be safely used for possible therapeutic benefits.
The efficiency of bankruptcy proceedings and the severity of insolvency regulations in view of the implementation of the New Opportunity Policy
Authors: Banasik Przemysław , Morawska Sylwia , Prusak Błażej , Łukowski Michal , Pustułka Katarzyna
Published: October 2024

The article investigates the relationship between the efficiency of insolvency proceedings, as measured by their duration, and measures the severity of bankruptcy law toward debtors in 27 countries, of which 23 are EU. This objective was achieved using quantitative methods – Pearson’s correlation, pooled panel regression and Granger causality. Research shows no direct correlation between the two variables mentioned above. The increase in sanctions in bankruptcy law contributed to a decrease in the efficiency of insolvency proceedings. In addition, less stringent conditions concerning the time taken to file a bankruptcy petition translated into a shorter duration of insolvency proceedings. Therefore, supporting the New Opportunity Policy, we recommend that regulators focus on softening the legal requirements for filing a bankruptcy petition, for setting a time limit for filing and on reducing the sanctions for honest debtors, including those imposed for failure to file for bankruptcy within the period prescribed by law.
Woody Species Composition, Structure, and Diversity of Parkland and Coffee-Based Agroforestry Systems, Habro District, Eastern Ethiopia
Authors: Fantaye Yosef , Estifanos Solomon , Feyissa Samuel
Published: October 2024

Agroforestry practices in eastern Ethiopia are renowned for their multifunctional landscapes, contributing significantly to biodiversity conservation and enhancement. However, there is a lack of comprehensive studies on the diversity and structure of woody species within coffee-based and parkland agroforestry systems documented in a single study. This research aimed to evaluate the composition, diversity, and structure of woody species in these agroforestry systems. Conducted in the Habro district of eastern Ethiopia, the study involved randomly selecting sixteen plots for each agroforestry system. Inventory assessments of woody species were carried out using 40×40 and 20 m*20-meter plots for parkland and coffee-based systems respectively, and 5×5-meter plots for coffee shrubs. For trees with a diameter at breast height (DBH) of ≥2.5 cm, measurements of tree heights were taken. The study computed basal area, stem density, diameter, and height class distribution to characterize the structure of woody communities, and species diversity was also assessed. The findings revealed a total of 57 woody species across 31 families. Specifically, 38 woody species were recorded in parkland agroforestry, while 43 species were found in coffee-based agroforestry systems. Significant differences were observed in species diversity indices and structural parameters between the two agroforestry systems. The Shannon diversity index and richness were higher in coffee-based agroforestry compared to parkland systems. Additionally, the density and basal area of woody species were greater in coffee-based systems than in parkland agroforestry. Overall, both agroforestry systems were found to conserve a significant number of woody species, highlighting their potential to contribute to biodiversity conservation and informing future agroforestry management strategies in national programs.
Analysis of reconstructive interventions in case of failures in hiatal hernia surgery
Authors: Fedorov V. I. , Burmistrov M. V. , Sharapov T. L. , Sigal E. I.
Published: October 2024

INTRODUCTION. The method of laparoscopic fundoplication for hiatal hernia is today the most common surgical intervention for this pathology. However, there are a significant number of complications, one of the most severe is relapse of the disease. Today, according to the world literature, there is not enough information about the causes of relapse, methods of prevention and long-term postoperative results of reconstructive operations.

The OBJECTIVE was to analyze of reconstructive surgeries in patients who underwent surgery for gastroesophageal reflux disease associated with hiatal hernia.

METHODS AND MATERIALS. The work was performed on the basis of data from two clinics – Oncology Department ¹ 2 of the RCOD of the Ministry of Health of the Republic of Tatarstan and Thoracic Department ¹ 2 of the RCB of the Ministry of Health of the Republic of Tatarstan. 1,661 laparoscopic interventions were performed in patients with hiatal hernia. The basis of the work is the analysis of reconstructive operations in 99 patients.

RESULTS. The most common reasons for reconstructive operations were relapses of diseases in gastroesophageal reflux disease associated with a hiatal hernia: destruction and (or) migration of the fundoplication cuff – 77 (77 %) cases, recurrence of paraesophageal hiatal hernia – 10 (11 %). Reconstructive surgery in patients with relapse of hiatal hernia remains the method of choice and leads to positive results in 83 % of cases.

CONCLUSION. Surgical treatment of hiatal hernia should be carried out in a specialized hospital and experienced surgeons who own both laparoscopic and open methods of treating this pathology.