bluuebunny/crossref_metadata_2025 huggingface dataset:
Nuclear transport under stress phenocopies transport defects in models of C9Orf72 ALS
Authors: Semmelink Marije F.W. , Jafarinia Hamidreza , Wolters Justina C , Gheorghe Teodora , Mouton Sara N. , Steen Anton , Onck Patrick R. , Veenhoff Liesbeth M.
Published: April 2022

The nucleus is the hallmark of eukaryotic life and transport to and from the nucleus occurs through the nuclear pore complex (NPC). There is a multitude of data connecting the nuclear transport machinery – i.e. the NPCs and associated nuclear transport factors - to neurodegenerative diseases, but the mechanisms are not well understood. Using Saccharomyces cerevisiae, we systematically studied how the expression of polyPR and polyGA related to C9Orf72 amyotrophic lateral sclerosis impacts the nuclear transport machinery. We measured the abundance and localization of NPC components and transport factors, and assessed the kinetics of import and export by four transport receptors. PolyPR and polyGA cause distinct, and transport receptor dependent effects. We compared the specific changes in transport to those obtained when cells were exposed to different stress situations or mutations. This comparison showed similar patterns of transport defects in cells lacking specific NTRs and cells expressing polyPR. In contrast, polyGA expressing cells bear resemblance to stress conditions where energy maintenance is decreased. The similarity of the patterns of transport deficiencies suggests that polyPR has a direct effect on nuclear transport via NTRs, while polyGA impacts the energy state of the cell and subsequently changes transport.
Multiscale modeling of polymers filled with MWCNTs: the effect of dispersion, waviness, interphase and agglomerations
Authors: Polydoropoulou Panagiota , Tserpes Konstantinos , Pantelakis Spiros , Katsiropoulos Christos
Published: April 2022

Purpose

The purpose of this paper is the development of a multiscale model which simulates the effect of the dispersion, the waviness, the interphase geometry as well as the agglomerations of multi-walled carbon nanotubes (MWCNTs) on the Young’s modulus of a polymer filled with 0.4 Vol.% MWCNTs.

Design/methodology/approach

For the determination of the homogenized elastic properties of the hybrid material representative unit cells (RUCs) have been used. The predicted homogenized elastic properties were used for the prediction of the Young’s modulus of the filled material by simulating a finite element (FE) model of a tensile specimen. Moreover, the model has been validated by comparing the predicted values of the numerical analysis with experimental tensile results.

Findings

As the MWCNT agglomerates increase, the results showed a remarkable decrease of the Young’s modulus regarding the polymer filled with aligned MWCNTs while only slight differences on the Young’s modulus have been found in the case of randomly oriented MWCNTs. This might be attributed to the low concentration of the MWCNTs (0.4 Vol.%) into the polymer. For low MWCNTs concentrations, the interphase seems to have negligible effect on the Young’s modulus. Furthermore, as the MWCNTs waviness increases, a remarkable decrease of the Young’s modulus of the polymer filled with aligned MWCNTs is observed. In the case that MWCNTs are randomly dispersed into the polymer, both numerical and experimental results have been found to be consistent regarding the Young’s modulus.

Practical implications

The methodology used can be adopted by any system containing nanofillers.

Originality/value

Although several studies on the effect of the MWCNTs distribution on the Young’s modulus have been conducted, limited results exist by using a more realistic RUC including a periodic geometry of more than 20 MWCNTs with random orientation and a more realistic waviness of MWCNTs with aspect ratio exceeding 150.
Internet of things and consumer engagement on retail: state-of-the-art and future directions
Authors: Ajayi Samson , Loureiro Sandra Maria Correia , Langaro Daniela
Published: April 2022

Purpose

The growing complexity of consumer engagement (CE) due to the impact of Internet of things (IoT) has been attracting significant attention from both academics and industry practitioners especially in recent times. Hence, understanding this phenomenon remains very crucial to the body of knowledge. This study conducted a systematic review on IoT and CE with the aim of proposing future research opportunities using the TCCM model.

Design/methodology/approach

Extant literature studies were systematically examined by sourcing high ranking ABS journals from EBSCO, ScienceDirect and Emerald. A total of 58 articles were included in the final analysis of this research.

Findings

The analysis established the need to conduct more research on CE due to the impact of new technological implementation in retail. The results further suggest the need for extensive research across African countries and emerging markets to enable broader empirical generalizations of research outcomes. Using the TCCM framework, the authors indicated directions for future empirical research.

Originality/value

This study exposes the current trends in CE and IoT. The results and analysis are both compelling and verifiable, hence, establishing a firm base of reference for future research in related fields.
Green intellectual capital and green HRM enabling organizations go green: mediating role of green innovation
Authors: Ullah Sami , Mehmood Tariq , Ahmad Tooba
Published: April 2022

Purpose

This study aims to investigate the complex relationship between green intellectual capital (GIC), green human resource management (GHRM) and green innovation (GI) for improvement in the environmental performance (EP) of an organization.

Design/methodology/approach

The data collected from 456 food manufacturing firms in Pakistan was used for structural equation modeling through SmartPLS. Hypotheses were tested through path analysis, predictive relevance and effect size of variables.

Findings

The findings show that GIC and GHRM have no direct impact on EP; instead, GI plays a mediating role to make GIC and GHRM helpful in improving an organization’s EP. Also, the environmental strategies play a significant role in the EP and act as a moderator in the relationship between GI and EP.

Originality/value

The Global Climate Risk Index has ranked Pakistan as the fifth most vulnerable to climate change. Industrial activities are contributing significantly to carbon emissions, and therefore, it is vital to mitigate and adapt to climate change to improve the organization’s EP. The findings of this study show that GIC, GHRM and GI can significantly enhance the EP of food manufacturing firms in Pakistan.
Politics of governing NPM-led agencies in Pakistan: influence of contextual factors on agency autonomy and control
Authors: Rizwan Aisha , Salman Yaamina , Naveed Shabana
Published: April 2022

Purpose

This article aims to empirically investigate the influence of socio-cultural and political factors and actors on the perceived autonomy and control of state agencies in Pakistan. Taking an institutional perspective, which envisages a diverse course of agency reforms, owed to varied national cultures, historical paths and traditional mindsets, the authors argue that the institutional theory provides an explanation to the autonomy and control status of the agencies.

Design/methodology/approach

Data were collected from 39 senior public officials and governing board members in federal agencies by conducting in-depth semi-structured interviews. Thematic analysis was performed using NVivo-12 for data analysis.

Findings

The results disclose that the agencies operate within an overriding politico-administrative culture of intervention and supremacy of the central government. There is a close relationship between the political actors and actors' implementing agents, the bureaucrats. Although the disaggregated public agencies are created under the agency model, a culture of political influence and control still prevails within them. Among the socio-cultural factors, corruption is reported as a critical influencing factor for agency autonomy.

Research limitations/implications

The study emphasizes the need to adapt and modify agencification practices in developing countries based on the political, socio-cultural and administrative contextual factors and actors and the varying degrees of influence the practices exercise over the Government machinery.

Originality/value

This study unveils the implications of the new public management (NPM)-led agency model in Pakistan, which was primarily adopted as a part of the structural adjustment program (SAP) under loan conditionality from international donor agencies and explores the indigenous doctrines that govern agencies functioning under ministries.
National Innovation Demonstration Zone policy and city innovation capability – a quasi-natural experimental analysis
Authors: Aisaiti Gulizhaer , Xie Jiaping , Zhang Tingting
Published: April 2022

Purpose

This paper aims to understand the relationship between the National Innovation Demonstration Zone policy and city innovation capability and the underlying mechanisms.

Design/methodology/approach

This paper collects panel data of 283 Chinese cities from 2006 to 2018 for the quasi-natural experiment of National Independent Demonstration Zone (NIDZ) policy. It applies the difference-in-difference (DID) method to study the impact of NIDZ policy on city innovation capability and its underlying mechanism to enhance it.

Findings

The empirical result indicates that the establishment of NIDZ significantly enhances the city's innovation capability, which was verified through a series of robustness tests. The mechanism analysis shows that the NIDZ promote the inflow and outflow of knowledge, which implies NIDZ enhances the innovation capability of cities by facilitating the innovation sharing impact. Heterogeneity analysis indicates that the higher degree of digitalization, the higher the government service level induce a more favourable policy effect. The policy effect is more significant in the cities with a higher marketization or the eastern developed region.

Practical implications

This study’s empirical findings suggest that it is essential to improve the digital infrastructure to accomplish the digital transformation and upgrading of NIDZ. The government should improve the service efficiency and reshape the city market environment to ensure the fair competition of science and technology enterprises.

Originality/value

The paper first proposed and empirically tested that innovation sharing is an important mechanism that can significantly enhance the city innovation capability. The authors analyse the heterogeneity of NIDZ from four aspects: digitalization level, marketization level, government service level, and regional development and expanded research boundaries.
A multi-level, time-series network analysis of the impact of youth peacebuilding on quality peace
Authors: Taylor Laura K. , Bähr Celia
Published: April 2022

Purpose

Over 60% of armed conflicts re-occur; the seed of future conflict is sown even as a peace agreement is signed. The cyclical nature of war calls for a focus on youth who can disrupt this pattern over time. Addressing this concern, the developmental peace-building model calls for a dynamic, multi-level and longitudinal approach. Using an innovative statistical approach, this study aims to investigate the associations among four youth peace-building dimensions and quality peace.

Design/methodology/approach

Multi-level time-series network analysis of a data set containing 193 countries and spanning the years between 2011 and 2020 was performed. This statistical approach allows for complex modelling that can reveal new patterns of how different youth peace-building dimensions (i.e. education, engagement, information, inclusion), identified through rapid evidence assessment, promote quality peace over time. Such a methodology not only assesses between-country differences but also within-country change.

Findings

While the within-country contemporaneous network shows positive links for education, the temporal network shows significant lagged effects for all four dimensions on quality peace. The between-country network indicates significant direct effects of education and information, on average, and indirect effects of inclusion and engagement, on quality peace.

Originality/value

This approach demonstrates a novel application of multi-level time-series network analysis to explore the dynamic development of quality peace, capturing both stability and change. The analysis illustrates how youth peace-building dimensions impact quality peace in the macro-system globally. This investigation of quality peace thus illustrates that the science of peace does not necessitate violent conflict.
The value of informal workplace learning for police education teachers’ professional development
Authors: Holmgren Robert , Sjöberg David
Published: April 2022

Purpose

The purpose of this study is to explore Swedish police education teachers’ informal workplace learning and its perceived value for their professional development. Two categories of teachers, police teachers and university teachers, with different professional knowledge and experience, work together at the police education unit.

Design/methodology/approach

The method used was in-depth interviews with teachers working at a Swedish police education unit.

Findings

Informal workplace learning was perceived by both teacher groups to be of great value for gaining knowledge about the local practice and for their professional development. Their learning emerged in discussions, observations and practically oriented activities in their daily work. Four conclusions: firstly, the teachers’ informal workplace learning was socially and practice-oriented and learning emerged in a collaborative, reciprocal and active process. Secondly, the embodied nature of the learning is evident in the teachers’ joint activities in the teaching practice. Thirdly, it takes time and active involvement in the local practice to become a professional teacher in this kind of education. Fourthly, an educational structure where academic knowledge and experience can be integrated with police knowledge and experience constitutes an important basis for teachers’ professional development in police education and training.

Originality/value

The study’s focus on police education and the professional development of teachers in this specific practice contributes to increased knowledge of the social, practice-oriented and embodied nature of informal workplace learning.
A methodological framework for quantitative risk analysis in container shipping operations
Authors: Nguyen Son , Chen Peggy Shu-Ling , Du Yuquan
Published: April 2022

Purpose

Container shipping is a crucial component of the global supply chain that is affected by a large range of operational risks with high uncertainty, threatening the stability of service, manufacture, distribution and profitability of involved parties. However, quantitative risk analysis (QRA) of container shipping operational risk (CSOR) is being obstructed by the lack of a well-established theoretical structure to guide deeper research efforts. This paper proposes a methodological framework to strengthen the quality and reliability of CSOR analysis (CSORA).

Design/methodology/approach

Focusing on addressing uncertainties, the framework establishes a solid, overarching and updated basis for quantitative CSORA. The framework consists of clearly defined elements and processes, including knowledge establishing, information gathering, aggregating multiple sources of data (social/deliberative and mathematical/statistical), calculating risk and uncertainty level and presenting and interpreting quantified results. The framework is applied in a case study of three container shipping companies in Vietnam.

Findings

Various methodological contributions were rendered regarding CSOR characteristics, settings of analysis models, handling of uncertainties and result interpretation. The empirical study also generated valuable managerial implications regarding CSOR management policies.

Originality/value

This paper fills the gap of an updated framework for CSORA considering the recent advancements of container shipping operations and risk management. The framework can be used by both practitioners as a tool for CSORA and scholars as a test bench to facilitate the comparison and development of QRA models.
The impact of role overload on job crafting from the perspective of construal level theory
Authors: Chen Long , Du Yana
Published: April 2022

Purpose

Previous studies have vague views about whether employees who are required to complete large amounts of work (i.e. role overload) would proactively create a change in their job characteristics (i.e. job crafting), because the cognitive mechanism underlying the nexus between role overload and job crafting is unclear. The aim of this study is to identify why and when role overload has an impact on job crafting.

Design/methodology/approach

This study builds a second-stage moderated mediation model. Using a two-wave panel field study of 213 employee–supervisor matched data, this study examines the proposed hypotheses.

Findings

Results show that role overload decreases construal level, which can determine the tendency of employees to focus on the feasibility (low level of construal) or desirability (high level of construal) of behaviors. Goal self-concordance is the degree to which employees pursue their personal goals based on feelings of personal interests and values. The authors find that goal self-concordance guides employees who have higher levels of construal to exert more effort in job crafting. The authors further find that goal self-concordance moderates the mediating role of construal level. Specifically, for employees in pursuit of self-concordant goals, role overload reduces their construal level, resulting in less effort in job crafting. For employees who do not pursue self-concordant goals, role overload decreases their construal level, thereby improving job crafting.

Originality/value

The findings of this study enrich the literature on role overload and job crafting by revealing the mechanism and boundary conditions of the relationship between role overload and job crafting.
Job crafting, meaningfulness and affective commitment by gig workers towards crowdsourcing platforms
Authors: Mousa Mohamed , Chaouali Walid
Published: April 2022

Purpose

Through focusing on gig workers registered in three crowdsourcing platforms, the authors investigate how individual and collaborative job crafting may be positively related to the meaningful work and affective commitment those gig workers develop towards the crowdsourcing platforms they register in.

Design/methodology/approach

The authors employed a quantitative research method in which they focused on date from surveys completed by 327 gig workers. They tested the hypotheses using SmartPLS 3, which is more suitable when dealing with complex models, non-normal data, small samples and higher-order constructs.

Findings

The results showed that the proactive behaviour embedded within both individual and collaborative job crafting may lead to a sense of meaningfulness for gig workers and subsequently, their affective commitment towards the crowdsourcing platforms they register in. Specifically, the more gig workers undertake individual (H1) and collaborative (H2) job crafting behaviour, the greater the sense of meaningfulness they develop. Moreover, meaningfulness for gig workers positively affects their affective commitment towards the crowdsourcing platforms they register with (H3).

Originality/value

To the best of the authors' knowledge, this study is the first of its kind in the context of France and the European Union to focus on job crafting and its effect on both meaningful work and the affective commitment of non-traditional workers. This paper contributes by filling a gap in human resource (HR) management, in which empirical studies that address gig work have been limited so far.
Tryst with the unknown: navigating an unplanned transition to online examinations
Authors: Mumtaz Sabiha , Parahoo Sanjai K. , Gupta Namrata , Harvey Heather L.
Published: April 2022

Purpose

This paper aims to investigate the major challenges faced and lessons learned during the unplanned transition to online examinations (OE) at a traditional university following the COVID-19 pandemic.

Design/methodology/approach

This exploratory study involved two distinct samples (110 students and 30 instructors) drawn from a large public university and triangulated the qualitative and quantitative data to analyze how the university navigated the unplanned transition to OE.

Findings

The university faced several challenges related to a lack of proper institutional infrastructure, non-familiarity of the stakeholders with OE, lack of effective communication, limited student access to technology resources because of socio-economic impediments and academic integrity issues.

Practical implications

Short- and medium-term recommendations are proposed to enable continuity of teaching and learning in future emergency situations, including the establishment of technology-enabled exam centers, as well as strategies to assure instructor readiness for OE, academic integrity among students and the validity of the evaluation procedure for future OE.

Originality/value

This study shows how the unplanned transition to OE in a public university exposed new challenges for conducting OE, particularly in resource challenged emerging countries, where full integration of OE was a new experience and prior knowledge of potential issues was lacking.
Reconciling stakeholder demands: a social dominance perspective
Authors: Orudzheva Leyla
Published: April 2022

Purpose

The purpose of this study is to investigate how a higher status of one stakeholder group relates to the outcomes of stakeholder–organization relationship with other lower status stakeholder groups.

Design/methodology/approach

This conceptual paper uses insights from resource dependence theory while applying the tenets of social dominance theory (SDT) to develop a model with testable propositions explaining the variability with regard to stakeholder dominance and the resulting outcome in terms of (un)favorable organizational responsiveness to other stakeholder demands.

Findings

Firm’s behavior or decisions regarding a particular stakeholder group may be influenced by dominant hierarchical status of another stakeholder group if the latter considers that their respective interests are misaligned and is not willing to compromise. The argument build in this paper indicates that it is likely that the influence of the dominant stakeholder group will undermine stakeholders from a subordinate group.

Originality/value

This paper contributes to two distinct literature streams. First, this paper extends research on stakeholder responsiveness exploring the triadic relationship, particularly focusing on stakeholders’ perspective that has been given much less attention in prior literature. Second, this paper extends the application of the SDT to a stakeholder relationship context potentially allowing for a more parsimonious theory.
Joint inversion of muon tomography and gravity gradiometry for improved monitoring of steam‐assisted gravity drainage reservoirs
Authors: Pieczonka Sara , Schouten Doug , Braun Alexander
Published: April 2022

Steam‐assisted gravity drainage reservoirs require an immense amount of energy and water resources, and proper monitoring of steam evolution and depletion patterns is integral to the economic and environmental efficiency of the operation. Muon tomography is a passive sensing technique, which has proven to successfully model density anomalies in a variety of applications but has not yet been applied to the oil and gas field. A previous study simulated muon intensity data to model density changes in a realistic steam‐assisted gravity drainage reservoir at 1.25 and 5 years after initial production. The results showed that muon tomography is a promising technique for monitoring steam‐assisted gravity drainage reservoirs with high spatial resolution and over short time intervals of weeks to months. Here we demonstrate the advantage of using vertical gravity gradient data and muon tomography data in a joint inversion to improve the muon‐only inverse models. Forward models for simulated muon and gravity gradient data are jointly inverted for a realistic steam‐assisted gravity drainage reservoir at 230 and 130 m total vertical depth at 1.25 years after initial production. Results show that the addition of gravity gradient data helps to constrain the density change models mainly in depth and to a smaller extent laterally. For a sparse muon sensor array of 48 sensors over a reservoir at depth, the joint inversion using gravity gradient data reduces the difference between the inverse and true model by 12% compared to a muon‐only inversion. The improvement is smaller at depth with 6%. The improvement in resolvability metrics is summarized, and limitations are discussed. The addition of multiple data types in a joint inversion improves the resulting models leading to an overall decrease in model uncertainty which can be used for improved operational efficiency in steam‐assisted gravity drainage operations.
Autism: an ‘epidemic’ of contemporary times?
Authors: de Araujo Ceres Alves
Published: April 2022

The text discusses the growing incidence of autism in the world, presents an understanding of autism from the point of view of analytical psychology, and reflects on the treatment of autistic patients. Today, it is understood that autism is part of a continuum of characteristics on a spectrum with biological and congenital causes. It is a non‐specific picture resulting from multiple causations of non‐linear factors. Autism is a neuro‐developmental disorder characterized by a triad of symptoms: persistent deficits in social communication and social interaction, and restricted and repetitive patterns of behaviours, interests, or activities. Autism spectrum disorder must be considered as a clinical entity, with current clearly defined characteristics. It is an extremely complex condition, which requires multidisciplinary approaches aiming at the possibility of prognosis and effective therapeutic approaches. This paper explores how a disturbance may occur from the intra‐uterine phase, in which matriarchal experiences do not constellate. The structuring function of the patriarchal organization can then become dominant, and people with autism need understanding and help to organize their world and learn to live in it. As they don't have the capacity to structure consciousness through the matriarchal archetype, they rely entirely on the structuring and organizing capacity of the Father archetype.
Migratory phenomenon and expressive sandwork in vulnerable populations
Authors: Deligiannis Ana , Pinilla Mónica
Published: April 2022

In these times the migratory phenomenon is a crisis with alarming dimensions worldwide. Wars, human rights violations and violence within borders have pushed many people to seek asylum or have forced internal displacement. We approach this phenomenon taking into account the cultural complexes, understanding it as a process with multiple psychological, social and existential effects for those who suffer it. We find these effects symbolized in many of the processes of the children participating in Expressive Sandwork projects. Expressive Sandwork is a transcultural, non‐verbal method of therapeutic care that offers psychological support to children from vulnerable populations where psychotherapy is deficient or non‐existent. The aim is to allow the emergence of images that favour reconnection with the child’s creative potential, activating the process of self‐regulation of the psyche. Its basis in symbolic processes and empathetic accompaniment makes it a Jungian psychosocial intervention for these times of transition. In Latin America, Expressive Sandwork projects have been implemented in Colombia and Argentina. Two examples of the participating children are presented.
Assisted dying: reflections on the psychological process
Authors: Kelly Tom
Published: April 2022

This paper explores the question of assisted dying from both a legal and psychological perspective within the legal parameters in place at the time of writing of this paper. Links are made between Kohut’s notion of an acceptance of the finiteness of existence and of transience as one of several indicators of the maturation and transformation of archaic narcissism, and Jung’s notion of the readiness and ability to ‘die with life’ as the goal of the second half of life. The author raises awareness of the importance of the need for clarity with regard to these issues on the part of therapists who may be required to provide an evaluation of a patient’s admissibility to a service of assisted dying.
Exile and the kingdom: integration of an exiled family
Authors: Porto Bráulio
Published: April 2022

The subject of exile is a ubiquitous global theme. The result of multiple factors, it insinuates itself into events affecting people’s daily lives and the development of countries. Beyond politics, a psychological reading enables us to reflect on its impact, not only on the individual or group but also in relation to the exiled family. The concept of a mythical or archetypal family can help us to clarify what emerges from contact between two communities and the challenges in their encounter. The study of a specific case – Portuguese families adjusting to life in a French‐speaking region of Switzerland – reveals a pattern reproduced elsewhere, even though separate in time and space. The cultural shock emanating from a background and approach of different dynamics leads to psychological resistance on both sides – and to a negative prognosis for cultural integration. Analytical work with exiled children and adolescents allows us to glimpse how this theme intertwines with personal psychologies, pointing to its creative solution through the resolution of conflict and openness to diversity – as carried forward by new generations. It is they who are open to multicultural values, showing simultaneously a respect for ancestry and a desire for renewal.
Civilization within the heart: the image and meaning of ‘civilization’ and ‘culture’ in Chinese characters
Authors: Shen Heyong
Published: April 2022

‘Civilization in Transition’ was the theme of the JAP conference in 2021, and also the reality we are facing today, especially amidst the pandemic of COVID‐19. From an oriental perspective, within the context of Psychology of the Heart, the author presents his thoughts in this paper, ‘Civilization within the heart: the image and meaning of “civilization” and “culture” in Chinese characters’. The meaning of the heart is at the core of Chinese culture, as well as Chinese philosophy and psychology. Most of the basic psychological terms in Chinese characters are formed originally with the images of the heart; even the Chinese character for ‘culture’ and ‘civilization’. C.G. Jung learned Chinese characters, and named them with I Ching symbols as readable archetypes. Today in world affairs we are confronted with highly turbulent and uncertain conditions that threaten any sense of coherent meaning, both personally and collectively. Jung’s insights gained from the I Ching and his reflections on analytical psychology are still inspiring us. The images and meaning of the hexagrams which C.G. Jung used: ‘Ting’ (The Cauldron), ‘Bi’ (Grace), and ‘Chin’ (Progress), are the main threads of this paper and presentation, ‘Civilization within the Heart’, responding to the theme ‘Civilization in Transition’.
Innocents, psychopaths and the imagination
Authors: Wahba Liliana Liviano
Published: April 2022

This article reflects on the manipulative practices of autocratic populist leaders in North and South America and looks at their speeches, which appeal to followers who desire love and protection, or who seek an outlet for aggressive impulses. Jung’s considerations regarding the annihilation of the other, evil and the unconsciousness of the masses – manipulated for purposes of subjugation – are important for understanding the risks that threaten society. The behaviour of unscrupulous leaders seized by power complexes, reinforced by psychopathic traits in clinic and culture, creates an increasing number of victims. A lack of imagination for evil is behind the absence of malice as a defence and the idealization which opens doors to the violence of totalitarian leaders and of dominant figures in social and family relationships. The polarities evil‐innocence and dominator‐dominated are severely dissociated in contemporary society, endorsing Jung’s vision as a warning against destructiveness.
The ‘Oscar curse’ or the price of women’s development
Authors: Gimenez Ramos Denise
Published: April 2022

This article aims to reflect on the unconscious dynamics that sustain the shocking increase in feminicide in the world. It is observed that psychological and physical violence by the intimate partner has numerous facets, especially when the woman gains more or has more professional success than her partner. This violence can take a subtle form as rejection and betrayal in order to hurt the woman and destroy her self‐esteem and success. Based on numerous studies and bibliography it is demonstrated that the main cause of violence by the intimate partner is the fear of the power of the feminine that has been present throughout history. Despite the evolution of women, historical violence reverberates in the 21st century as an intergenerational trauma causing great suffering in families and disturbances in interpersonal relationships.
On Mystery: explorations on the experience of the numinous
Authors: Benchín Federico
Published: April 2022

The present work aims to present ideas about the notion of ‘Mystery’, based on the contributions of various thinkers from different areas of knowledge. It will focus especially on the experience itself, that is, on the human possibility of generating the mystical experience and conceptualizing the dimension from contact with it. Concepts such as ‘Homo Mysticus’ (Erich Neumann), ‘Numinous’ (Rudolf Otto), ‘Synchronicity’ and ‘Self’ (Carl G. Jung) will be developed, approaching them from a psychological perspective. A distinction between two different categories of contact is proposed in the article: violent experiences and subtle experiences.

The referential framework of analytical psychology enables the possibility of a transcendent and immaterial realm creatively linked to psychic reality, as well as an attempt to understand it. The conceptualization of the symbolic from the Jungian worldview allows us to understand the experience of Mystery from a psychological point of view in relation to the surrounding world. The idea is even raised that the ultimate (and implicit) purpose of the analysis is the manifestation of Mystery, a general name that could encompass the different phenomenological experiences.

Is it possible that such experiences occur in the cultural circumstances of the present? What place does Mystery occupy in these times? What forms could it take? By observing dreams, imaginations and synchronicities, experiences of the mysterious will be explored in the context of contemporary Jungian analysis.
Creating our own Black Books: keeping a journal as a loom of life
Authors: Pinilla Pineda Mónica
Published: April 2022

Jung’s The Black Books are annotations of his inner world after his process of self‐experimentation, which he called his ‘confrontation with the unconscious’. They preceded The Red Book in which, as a scribe, he reworked his initial notes and drawings. This was the raw material for the work that Jung developed over the rest of his life. From his experimentation, he formulated the method of active imagination and the concept of the transcendent function, a psychological function that creates symbols and integrates the unconscious contents in consciousness. Jung invites us, with his experience, to write and paint our own Black Books and to explore our inner images. With this proposal to keep a journal as a loom of life, we welcome his invitation, which allows us to weave and integrate the visible and invisible substances of our lives. Our intention for the journalling is to provide a space for the unfolding of the individuation process. In Jung’s invitation we see that a life that does not confront itself cannot be realized as such.
The analyst as user illusion: therapy in the time of COVID‐19
Authors: Leutrum Matthias
Published: April 2022

In his essay The Spiritual Problem of Modern Man, Jung states that ‘The spiritual problem of modern man is one of those questions which are so much part of the age we live in that we cannot see them in proper perspective. Modern man is an entirely new phenomenon; a modern problem is one which has just arisen and whose answer still lies in the future’ (Jung 1928, para. 148). During the pandemic, analytic treatment largely moved to online platforms. I propose an examination of the implications of video therapy for our experience and understanding of the analytic frame and container. Through the introduction of Marina Abramović’s performance piece entitled The Artist is Present, which took place at MoMA, New York, in 2010, I explore some reverberations of technologically‐mediated sessions. By putting Abramović’s piece in context with some of my experiences, I draw conclusions regarding a technologically‐mediated therapeutic paradigm. Supported by writings from authors André Sassenfeld, Tor Nørretranders and Iain McGilchrist, I introduce the concept of ‘exformation’ and investigate different neuroscientific presets of human perception and communication. I will ask how they might affect online therapeutic work and our experience of an embodied versus a virtual co‐presence.
Clinical algorithms for identification and management of delay in the progression of first and second stage of labour
Authors: Pasquale J , Chamillard M , Diaz V , Gialdini C , Bonet M , Oladapo OT , Abalos E , Algorithms Working Group for the WHO Intrapartum Care
Published: April 2022

Aim

To develop clinical algorithms for the assessment and management of slow progress of labour.

Population

Low‐risk singleton, term, pregnant women in labour.

Setting

Institutional births in low‐ and middle‐income countries.

Search strategy

We systematically reviewed the literature on normal labour progression, and guidance on clinical management of abnormally slow progression from 1 December 2015 to 1 October 2020 from relevant international guidelines, Cochrane reviews and primary research studies in PubMed by searching for international and national guidance documents, electronic databases and published systematic reviews using relevant keywords.

Case scenarios

We developed two clinical algorithms: one for abnormally slow labour progression and arrest during first stage and one for the second stage. The algorithms provide definitions of suspected and confirmed slow progress of labour or arrest, initial assessment and ongoing monitoring, differential diagnosis, and management of the abnormalities, as well as links to other algorithms for labour management.

Conclusions

Identifying abnormal progress of labour is often challenging. These algorithms may help healthcare providers identify abnormal labour progress and institute prompt management or referral where needed but also reduce misdiagnosis and unnecessary use of interventions to accelerate labour.

Tweetable abstract

Evidence‐based clinical algorithms may help and standardize early identification and management of abnormally slow labour progress or arrest.

Tweetable abstract
Structural characterization and immunomodulatory effects of extracellular polysaccharide from Lactobacillus paracasei VL8 obtained by gradient ethanol precipitation
Authors: Liu Yuwei , Mao Kemin , Zhang Nan , Chitrakar Bimal , Huang Pimiao , Wang Xianghong , Yang, Bing , Sang Yaxin
Published: April 2022

In this study, gradient ethanol precipitation method was applied to obtain the extracellular polysaccharides of Lactobacillus paracasei VL8 (VL8‐EPS). The yields, physicochemical properties, and immunomodulatory effects of VL8‐EPS obtained by precipitation at different ethanol concentrations (30%, 50%, and 70%, v/v) were compared. The results showed that VL8‐EPSs were high molecular weight sulfated heteropolysaccharides, composed mainly of glucose and galactose, and the alteration of ethanol concentration had an effect on their chemical compositions, molecular weight distributions, monosaccharide composition, and surface structure, while the primary structure remained the same. Among the three polysaccharide fractions, VL8‐EPS50 displayed better immunomodulatory activities compared with VL8‐EPS30 and VL8‐EPS70. VL8‐EPS50 was found to exert immunomodulatory effects by enhancing the phagocytic activity of RAW264.7 cells and to promote their secretion of more nitric oxide; it also showed stronger thermal and solution stability. In summary, there was a correlation between the structural characteristics of polysaccharides and their immunomodulatory activity, and VL8‐EPS50 was preferentially used for in vivo immunomodulatory activity.

Practical Application

This study opens up the source of raw materials for functional foods, which can provide some theoretical basis for the research and development of extracellular polysaccharides of lactic acid bacteria and promote their application in the future development of food industry.
A comparative study of acute heat tolerance and meat quality in three chicken breeds
Authors: Liang Hsiao‐Mei , Chang Ti‐Chun , Lin Der‐Yuh , Yang Kuo‐Tai , Cheng Fu‐Yuan
Published: April 2022

In order to breed a strain that has heat tolerance and meat productivity, the commercial red‐feathered Taiwan native chickens were male (F group), and heat stress resistant strain Taiwan native chickens (Taishu‐9, bred by the Taiwan Livestock Research Institute) were female (TR9 group) to hybridize to generate offspring (F9 group). Three breeds of birds (male) were conducted to compare acute heat stress and meat quality. At 12 weeks of age, TR9 group showed the significantly lowest activity of plasma creatine kinase upon acute heat stress which indicated heat stress resistant in TR9 group as expected. In addition, only limited thermoregulation was obtained in F9 group, while F group exhibited almost no acute heat stress tolerance ability. After slaughtered at 16 weeks of age, the F group revealed poor meat quality in breast meat as pale, soft, and exudative (PSE)‐like muscle samples according to CIE L* and pH value. The F9 group was an offspring of TR9 group with heat tolerance, but it only demonstrated limitation of heat resistance. However, the improve meat quality was obtained in F9 group compared to F group, and that may be contributed from better anti‐stress as like as TR9 group during slaughtering process.
International guidelines regarding the role of IVIG in the management of Rh‐ and ABO‐mediated haemolytic disease of the newborn
Authors: Lieberman Lani , Lopriore Enrico , Baker Jillian M. , Bercovitz Rachel S. , Christensen Robert D. , Crighton Gemma , Delaney Meghan , Goel Ruchika , Hendrickson Jeanne E. , Keir Amy , Landry Denise , La Rocca Ursula , Lemyre Brigitte , Maier Rolf F. , Muniz‐Diaz Eduardo , Nahirniak Susan , New Helen V. , Pavenski Katerina , dos Santos Maria Cristina Pessoa , Ramsey Glenn , Shehata Nadine ,   for the International Collaboration for Transfusion Medicine Guidelines (ICTMG)
Published: April 2022

Haemolytic disease of the newborn (HDN) can be associated with significant morbidity. Prompt treatment with intensive phototherapy (PT) and exchange transfusions (ETs) can dramatically improve outcomes. ET is invasive and associated with risks. Intravenous immunoglobulin (IVIG) may be an alternative therapy to prevent use of ET. An international panel of experts was convened to develop evidence‐based recommendations regarding the effectiveness and safety of IVIG to reduce the need for ETs, improve neurocognitive outcomes, reduce bilirubin level, reduce the frequency of red blood cell (RBC) transfusions and severity of anaemia, and/or reduce duration of hospitalization for neonates with Rh or ABO‐mediated HDN. We used a systematic approach to search and review the literature and then develop recommendations from published data. These recommendations conclude that IVIG should not be routinely used to treat Rh or ABO antibody‐mediated HDN. In situations where hyperbilirubinaemia is severe (and ET is imminent), or when ET is not readily available, the role of IVIG is unclear. High‐quality studies are urgently needed to assess the optimal use of IVIG in patients with HDN.
Invasive cervical cancer audit: What lessons can we learn locally and where would we stand with regard to duty of candour?
Authors: Burgess Helen , Ellis Kay , Gillespie Alan M. , Macdonald Madeleine C. , Palmer Julia E.
Published: April 2022

Objective

To identify lessons learned locally from the invasive cervical cancer audit. To estimate the impact that the application of ‘Duty of Candour’ may have upon our future service provision.

Methods

Retrospective cohort study with interval analysis of all women diagnosed with cervical cancer at Sheffield Teaching Hospitals NHS Foundation Trust between 1 April 2007 to 31 December 2019. Data were collected prospectively with retrospective categorisation by screening history and invasive cervical cancer audit outcomes as satisfactory, satisfactory with learning points, and unsatisfactory.

Statistical analysis was performed using the chi‐squared test and paired t‐test.

Results

Cervical cancer was diagnosed in 344 women. Seventy‐eight (23%) had no record of prior cervical cytology, 108 (31%) had delayed attendance to the screening programme, 102 (30%) were detected by routine screening, and 56 (16%) were screening programme compliant. Satisfactory management was undertaken in 301 (87.5%) cases, 26 cases (7.5%) were satisfactory with learning points, and 17 cases (5%) were considered as unsatisfactory.

Conclusions

Seventeen cases were applicable to the Duty of Candour process equating to 1.3 cases per year, incurring minimal impact upon future service provision. Invasive audit categorisation is subject to bias, however, with the potential for considerable intra‐ and inter‐observer variation; the authors accordingly recommend that a further study be conducted to investigate both the consistency and reproducibility of the invasive cervical cancer audit categorisation.
Epidemiology of skin diseases in Germany: systematic review of the current state of research – part 2: non‐infectious skin diseases
Authors: Hansen Inga , Augustin Matthias , Schäfer Ines , Mohr Nicole
Published: April 2022

The aim of this work was to systematically collect all previously published population‐based epidemiological data on skin diseases in Germany. The present part 2 of the publication series deals with non‐infectious skin diseases. The results on cutaneous tumor diseases (part 1) and infectious skin diseases (part 3) form the other parts of this publication series.

A systematic literature search was performed using PubMed/MEDLINE for the period of the last 15 years. With the aim of including all dermatologic diseases, a diagnostic list was developed based on the ICD‐11 catalogue. This list included 1,347 skin diseases and formed the basis for the search.

The literature search yielded 4,650 hits, of which 72 were included in the synthesis. Among them were 37 publications on non‐infectious skin diseases. Among these, psoriasis and atopic eczema were the most common. The highest lifetime prevalence was found for acne.

This work is the first systematic literature review that aimed to report all available epidemiological data on skin diseases in Germany. It was found that representative data on many non‐infectious diseases are not yet available. Among the included studies, there was a high heterogeneity regarding the methodology. Nevertheless, the utility of these epidemiological data is wide‐ranging and can serve as a reference of various epidemiological questions.