bluuebunny/crossref_metadata_2025 huggingface dataset:
The macroprolactinemia phenomenon: origin and clinical diagnostic significance
Authors: Bulatov A. A.
Published: September 2019

The authors discuss the experimental and clinical data on the origin, properties, and diagnostic value of serum immunoreactive prolactin (irPRL) with a high molecular mass (macroprolactin, 100K-PRL). This form predominates in the blood of about 25% of women of a reproductive age with hyperprolactinemia. Comparison of the biochemical, immunochemical, and functional characteristics of the blood serum 100K-PRL and the monomeric fraction irPRL (23K-PRL) showed them to differ in principle. A low biological activity of 100K-PRL explains the absence of typical clinical signs of hyperprolactinemia in many women with macroprolactinemia. In contrast to 23K-PRL, 100K.-PRL weakly reacts to stimulants and inhibitors of PRL secretion by the pituitary. PRL-binding protein, apparently an immunoglobulin, is the basis of fraction 100K-PRL. The authors consider that analysis of not only total irPRL in the blood, but of its high and low-molecular forms be included in the algorithm of diagnostic search in some forms of hyperprolactinemia. This will help determine the treatment policy, because moderate hyperprolactinemia with predominating 100K- PRL as a rule cannot be corrected by dopamine agonists.
Aprender desde la experiencia histórica. Representaciones del profesorado sobre el uso de la historia oral como estrategia didáctica
Authors: Meneses Varas Belén , González-Monfort Neus , Santisteban Fernández Antoni
Published: September 2019

El artículo aborda la experiencia histórica (EH) como un aspecto fundamental en la construcción del conocimiento histórico escolar. El objetivo del estudio es definir el significado de EH desde la didáctica de las ciencias sociales, reconocer su relación con la formación del pensamiento histórico y las formas de desarrollarla en los procesos de enseñanza y aprendizaje. Para ello se indaga en las representaciones del profesorado sobre el concepto de EH a partir de las reflexiones sobre sus prácticas de aula al utilizar la historia oral. Es una investigación cualitativa de tipo interpretativa, basada en un estudio de casos, que utiliza métodos mixtos para el análisis de los datos obtenidos de 33 cuestionarios y 8 entrevistas en profundidad.Las representaciones del profesorado revelaron que la EH se asocia a tres dimensiones: vivencial, cognitiva y aplicada. En los procesos de enseñanza y aprendizaje las tres dimensiones deben actuar de manera dinámica e interrelacionadas para considerarse como EH. Es posible vincularla al pensamiento histórico como un aspecto indispensable para el desarrollo de sus competencias y para propiciar el protagonismo histórico del estudiante en la construcción de su conocimiento histórico. Las formas de desarrollar la EH en los procesos de enseñanza y aprendizaje son mediante el uso de recursos de tipo testimonial, la interpretación histórica y mediante metodologías activas orientadas a la participación ciudadana.
Os lugares do conceito de nação na narrativa de jovens estudantes da cidade de Ponta Grossa: passado, presente e futuro
Authors: Klüppel Giuvane de Souza
Published: September 2019

Parte de um projeto de pesquisa guarda-chuva de âmbito nacional intitulado «o país e o mundo em poucas palavras: narrativas de jovens sobre seus pertencimentos – implicações para o ensino de Ciências Humanas», este texto traz os resultados da análise de 277 respostas de alunos inseridos em quatro etapas de educação formal da cidade de Ponta Grossa, Paraná, Brasil. A consigna «por favor, conte a história do seu país» foi direciona a alunos matriculados em instituições de Ensino Fundamental, Médio, Superior e Pós-Graduação e coletada a partir de questionários de caráter qualitativo. A análise das respostas se deu a partir da disposição dos dados coletados em uma rede semântica de grafos elaborado para visualização em nuvem, possibilitando o exame de evocações e relações estabelecidas entre as palavras-chave dentro do conjunto narrativo. Os sentidos dados ao passado, os agentes da história e o lugar dos próprios narradores foram os elementos enfocados na investigação, que dialoga com os conceitos de consciência histórica (Rüsen, 2007) e narrativa mestra (Carretero; Van Alphen, 2014). Como resultado trazemos um panorama abarcando os elementos que são mobilizados nessa narrativa: suas características gerais, os sentidos dados à história e o lugar em que os alunos colocam a nação no passado (história), no presente (narrativa) e no futuro, a partir de suas expectativas e anseios.
Sistemas interétnicos, mirada etnográfica e investigación histórica en el Nororiente de Venezuela durante la época colonial
Authors: Tiapa Francisco
Published: September 2019

La región del Nororiente de Venezuela, durante la época colonial, estuvo caracterizada por el contraste entre diferentes grupos étnicos y culturales. La reconstrucción de estas divergencias ha requerido de la proyección de las bases teóricas del método etnográfico hacia ámbitos que implican no solo la alteridad en el tiempo, sino alteridad en el espacio. En este trabajo se ilustra cómo este método, más que ser una técnica de recolección de datos es en sí una mirada que permite la relativización de la cultura de referencia y la aproximación hacia visiones de mundo divergentes con el punto de vista del observador. En la primera parte, se argumenta la relevancia de la mirada etnográfica para la crítica a la cultura de referencia del analista y de su proyección hacia el estudio histórico de fronteras multiculturales. En la segunda parte, se ilustra la aplicación de esta perspectiva en las fronteras étnicas del Nororiente de Venezuela durante la época colonial. En esta sección, el énfasis se establece sobre su importancia como recurso de auto-crítica cultural, la configuración de la mirada desde la alteridad, la aprehensión de otras formas de irreflexividad cultural y el reconocimiento de las diversas formas de complejidad social. Finalmente, se abre la reflexión en torno a los límites analíticos derivados de la separación entre la mirada histórica y la antropológica, debido a sus potenciales sesgos etnocéntricos al abordar el estudio de las diferencias culturales en el tiempo.
Resistencias. La oposición interior del nacionalismo vasco a la dictadura de Franco (1937-1959)
Authors: Almeida Díez Adrián
Published: September 2019

Este artículo de investigación tiene por objetivo estudiar los procesos de resistencia al régimen franquista desarrollados por el nacionalismo vasco en el interior del País Vasco entre los años 1937 (año de la caída de Bilbao en manos franquistas) y 1959 (año de la aparición del grupo ETA). Basándose en la doble tipologización de las resistencias al poder desarrollada por el antropólogo James C. Scott en la ya clásica obra de Los Dominados y el Arte de la Resistencia, el artículo pretende realizar un análisis histórico que examine tanto las resistencias públicas y activistas (actos de sabotaje, preparación guerrillera, propaganda, etc.), como las resistencias basadas en el discurso oculto y centralizadas en la creación de los espacios de reproducción de una cultura disidente al poder (la cuadrilla, los grupos corales y folklóricos, la parroquia, etc.). La documentación consultada en los archivos especializados, fundamentalmente prensa y correspondencia de militantes y distintos grupos políticos nacionalistas (especialmente los colectivos juveniles), ha permitido descubrir la importancia del primer tipo de resistencia nacionalista al franquismo en el interior de los territorios vascos peninsulares, así como trazar una secuencia histórica entre esta resistencia activista y la primigenia formación del grupo Ekin, más adelante reconvertido en ETA.
Lʼarte come gioco: Bruno Munari e lʼinvenzione della video˗didattica
Authors: Articoni Angela
Published: September 2019

Nel copioso elenco di attività alle quali Bruno Munari si è dedicato nel corso della sua carriera, quella attinente alla didattica attiva attuata tramite video non è mai stata approfondita in modo articolato. In pochi si sono occupati di analizzare le metodologie adottate dall’artista in un’ottica che non sia impaludata soltanto nell’ambito dell’educazione artistica stricto sensu ma che esplori tutti i territori battuti da Munari. Il saggio si propone pertanto di esaminare la pioneristica trasmissione Costruire è facile della «TV dei ragazzi» e i video Lʼarte come gioco, frutto di una lunga attività didattica svolta in collaborazione con scuole e musei di tutto il mondo. Unʼanalisi dei video è imprescindibile per dimostrare sia la personalità di Munari, il suo trascendere ogni regola didattica affermata, sia il suo approccio ludico e fintamente disimpegnato nei confronti dei piccoli allievi: i bambini apprendono manipolando la materia, disegnando, creando collage e oggetti, e svolgendo altre piacevoli occupazioni che stimolano la loro creatività, attuando quello che è lʼapplicazione del «Metodo Bruno Munari», ancora allʼavanguardia.
Epileptic seizure recognition using EEG wavelet decomposition based on nonlinear and statistical features with support vector machine classification
Authors: Nabil Dib , Benali Radhwane , Bereksi Reguig Fethi
Published: September 2019

Epileptic seizure (ES) is a neurological brain dysfunction. ES can be detected using the electroencephalogram (EEG) signal. However, visual inspection of ES using long-time EEG recordings is a difficult, time-consuming and a costly procedure. Thus, automatic epilepsy recognition is of primary importance. In this paper, a new method is proposed for automatic ES recognition using short-time EEG recordings. The method is based on first decomposing the EEG signals on sub-signals using discrete wavelet transform. Then, from the obtained sub-signals, different non-linear parameters such as approximate entropy (ApEn), largest Lyapunov exponents (LLE) and statistical parameters are determined. These parameters along with phase entropies, calculated through higher order spectrum analysis, are used as an input vector of a multi-class support vector machine (MSVM) for ES recognition. The proposed method is evaluated using the standard EEG database developed by the Department of Epileptology, University of Bonn, Germany. The evaluation is carried out through a large number of classification experiments. Different statistical metrics namely Sensitivity (Se), Specificity (Sp) and classification accuracy (Ac) are calculated and compared to those obtained in the scientific research literature. The obtained results show that the proposed method achieves high accuracies, which are as good as the best existing state-of-the-art methods studied using the same EEG database.
Assimilation, hybridity and encountering. The cinematic representation of queer migrants from Muslim backgrounds living in Europe
Authors: Coll-Planas Gerard
Published: September 2019

Muslim migrants are the counter-figures through whom the modern Western identity is shaped. In Islamophobic discourses, they are constructed as inherently sexist and homophobic. In this ideological context, queer migrants coming from Muslim countries occupy an intersectional social location between Islamophobia and homophobia. In this paper we analyze the cinematic representation of queer migrants living in Europe coming from Muslim backgrounds. The aim of the paper is to analyze whether the films reproduce or subvert the Western “gay narrative”. The corpus of analysis is made up of 19 films which were studied through a process of categorization of the relevant fragments in a matrix. The films are classified in three categories according to their approach. The first gathers those films that hold an assimilationist discourse, according to which queer migrants should embrace the Western “gay narrative” and abandon the values of the communities of origin. In the second category, the films propose a hybrid perspective in which characters merge elements from both the country of residence and the cultural background of origin in the exploration of their sexuality and gender. The films in the third category revolve around a metaphorical relationship between a queer migrant and a native person, promoting a reflection on the possibilities of transformative encounters that break the boundaries between supposedly opposed social groups.
Die Frage nach dem wirklichen Julius Cäsar – und warum sie immer noch aktuell ist
Authors: Cardani Michele , Tamborini Marco
Published: September 2019

This paper takes into account Bertrand Russell’s, Francis H. Bradley’s, and Immanuel Kant’s arguments about “what is the real Julius Caesar” to examine (i) Russell’s characterization of analytic philosophy as a “new philosophy”, born as a revolt against idealism, and (ii) the actual relationship between Bradley and Kant. In order to understand who Russell was actually revolting against, we analyse the features of Bradley’s idealism and investigate how he understood and interpreted Kant’s transcendental revolution. By using the notion of Julius Caesar as a cogent comparative case study, we show that Bradley’s reading of Kant was not well-grounded. Therefore, we argue that Bradley’s interpretation of Hegel’s idealism was also unconventional. This misunderstanding in turn shaped and characterised Russell’s revolt against idealism. As a result, we show that analytic and continental philosophy began to part ways with the birth of what Russell calls new philosophy much earlier than their encounter at Davos. The reasons for this parting can be found in British idealists’ erroneous interpretation of Kant’s transcendental philosophy.
Das Hypothesenwesen
Authors: Hufendiek Rebekka
Published: September 2019

There is an eye-catching similarity in structure between Paul Rée’s Origin of Moral Sensations and Nietzsche’s Genealogy of Morals. Accordingly, the Genealogy has been understood as a riposte to Rée. I will argue in this paper that Nietzsche distances himself from Rée not only by developing alternative genealogies for moral concepts and institutions. Nietzsche’s main aim in criticizing Rée is to develop his own genealogical method that aims for historical adequacy, psychological adequacy, distinction of cause and function, acceptance of partial historical opacity and perspectivism.
A colorimetric method to measure oxidized, reduced and total glutathione levels in erythrocytes
Authors: Alisik Murat , Neselioglu Salim , Erel Ozcan
Published: September 2019

Background

The most important antioxidant for erythrocytes is glutathione. In this study, a non-enzymatic recycling spectrophotometric method was developed to measure oxidized and reduced glutathione (GSH) levels in erythrocytes. The newly developed method consists of two steps. In the first step, the levels of GSH were determined in the sample. Subsequently, total glutathione levels were measured by reducing the oxidized glutathione (GSSG) with sodium borohydride (NaBH4). Half of the difference between total glutathione and GSH gives the GSSG.

Results

The new method was linear between 0 and 3000 μmol/L (r2 = 0.999). The percentage recovery measured by the developed method was 100.2 ± 2.4%. The total precision of the total glutathione, GSH and GSSG was 1.26%, 1.02% and 6.65%, respectively. GSH levels were significantly lower in patients with type 2 diabetes mellitus (DM), while GSSG levels were significantly higher (p < 0.05). Hemoglobin A1c(HbA1c) levels were negatively correlated with GSH levels, whereas positively correlated with GSSG (p < 0.05).

Conclusions

In conclusion, this method is easy to apply in routine practice with high accuracy, precision and reproducibility.
The Coldness of Forgetting: OOO in Philosophy, Archaeology, and History
Authors: Harman Graham
Published: September 2019

This article begins by addressing a critique of my book Immaterialism by the archaeologists Þóra Pétursdóttirr and Bjørnar Olsen in their 2018 article “Theory Adrift.” As they see it, I restrict myself in Immaterialism to available historical documentation on the Dutch East India Company (VOC), and they wonder how my account might have changed if I had discussed more typical archaeological examples instead: wrecked and sunken ships, released ballast, deserted harbors, distributed goods, and derelict fortresses. In response, I argue that my account was not therefore non-archaeological, since ruins are the topic of archaeology only by accident: the real subject of the discipline is what Marshall McLuhan describes as “cold media,” in the sense that they are low in information. McLuhan’s distinction between hot and cold media is shown to be surprisingly analogous to Aristotle’s difference between continua and discrete substances, and some consequences are drawn from this analogy.
Surface features on aged 238Pu-doped Eu-monazite
Authors: Shiryaev Andrey A. , Burakov Boris E. , Nickolsky Maximillian S. , Yapaskurt Vasily O. , Pavlushin Anton D. , Grigoriev Mikhail S. , Vlasova Irina E.
Published: September 2019

Several 238Pu-doped Eu monazite single crystals stored at ambient conditions are monitored for 15 years using Scanning and Transmission electron microscopy, spectroscopy, diffraction and optical microscopy. Despite preservation of high crystalline quality, mechanical cracking and formation of small flakes is observed. After several month of aging, a new phase appeared on surfaces of the crystals, which later formed a continuous shell of most crystallographic faces. Electron diffraction indicated that the shell consists of submicron Pu-containing rhabdophanes. Its formation likely occurs due to combined action of atmospheric moisture and recrystallisation of radiation damage in monazite domains adjacent to external and internal surfaces. Extent of the rhabdophane formation appears to be influenced by crystallography and Pu content of corresponding growth sectors of the parent monazite. Whereas macroscopic rhabdophanes and monazites are relatively stable against irradiation, formation of sub-microscopic particles is a point of concern for development of monazite-based ceramic forms for actinide immobilization.
Oral Questions in the European Parliament: A Network Analysis
Authors: Jäckle Sebastian , Metz Thomas
Published: September 2019

Internal working structures within parliaments are notoriously hard to capture. While analyses based on bill co-sponsorship work for the US Congress, this approach is not feasible in many parliamentary systems. Drawing on data from the European Parliament’s legislative term of 2009–2014 this article shows that parliamentary questions can be another option. Members of the European Parliament may demand information from the Council or the Commission through oral questions. We take advantage of the fact that these questions are signed by their authors and construct a social network of members of the Parliament that support each other’s oral questions. This allows investigating how members and their groups and committees cooperate to control both Council and Commission. Our approach helps to map out the internal structure of the party groups and explore which forces shape the global network. We find that cooperation is mostly driven by party group membership with ALDE, Green/EFA, and GUENGL turning out as the most cohesive groups while SD is internally rather loosely connected. The second strongest clustering characteristic is a legislators’ native country.
Mobilität und Tourismus, ein Überblick über die Entwicklung in Österreich
Authors: Molitor Romain
Published: September 2019

Mobilität und Tourismus hängen zusammen; insofern werden auch die Treibhausgas-Emissionen im Tourismus maßgeblich vom Verkehr verursacht, wobei das Ausmaß der Treibhausgas-Emissionen vom gewählten Verkehrsmittel bei der Anreise abhängt. Für die Anreise der Österreich-Urlaubenden dominiert der Pkw. In Österreich werden von Destinationen, von Landestourismusorganisationen und von ministerieller Seite seit einigen Jahren Maßnahmen gesetzt, den Umweltverbund bei der Anreise und für die Mobilität vor Ort zu stärken. Diese reichen vom Einsatz bedarfsorientierter Verkehre bis zur Stärkung der Bahnanreise.
LAST MILE
Authors: Zehetgruber Christine
Published: September 2019

Damit nachhaltige Mobilität im Tourismus nicht nur eine Vision bleibt, benötigt es maßgeschneiderte Mobilitätsangebote, die auch die „letzte Meile“ mit berücksichtigen. Dies ist der Schwerpunkt des Interreg Europe Projektes LAST MILE, das unter österreichischer Leitung regionale Strategien für ländliche touristische Regionen beleuchtet. Innovativ ist darin die intensive Auseinandersetzung mit den notwendigen rechtlichen, institutionellen und ökonomischen Rahmenbedingungen. Darauf aufbauend entwickeln die Projektregionen nun konkrete Strategien um Barrieren für die Realisierung niederschwelliger flexibler Lösungen abzubauen.
СПЕЦИФІКА НАВЧАННЯ НІМЕЦЬКОЇ МОВИ ЯК СПЕЦІАЛЬНОСТІ В УМОВАХ ШТУЧНОГО СУБОРДИНАТИВНОГО БІЛІНГВІЗМУ
Authors: MARUNEVYCH Bozhena
Published: September 2019

Стаття присвячена дослідженню проблеми навчання німецької мови як спеціальності в умовах міжмовної взаємодії рідної та іноземної мов. На основі детального аналізу психологічного аспекту штучного субординативного білінгвізму обґрунтовано доцільність урахування фактора двомовності як об’єктивної реальності в навчальному процесі; виділено психолінгвістичну концепцію взаємодії мовних кодів у свідомості білінгва як визначальну для розробки сучасної методики навчання німецької мови в умовах штучного білінгвізму.
КАДРОВЕ ЗАБЕЗПЕЧЕННЯ ЗАПОЧАТКУВАННЯ ТА ПРОВАДЖЕННЯ ОСВІТНЬОЇ ДІЯЛЬНОСТІ У СФЕРІ ВИЩОЇ ОСВІТИ УКРАЇНИ
Authors: HELESH Anna
Published: September 2019

У статті представлено нормативно-правові документи, що регулюють сучасний порядок процедури ліцензування у сфері вищої освіти України, як виду господарської діяльності. Обґрунтовано зміст поняття процедури ліцензування освітньої діяльності та окремих її складових. Охарактеризовано освітні послуги, що підлягають ліцензування у сфері вищої освіти. Автором систематизовано та упорядковано кадрові вимоги щодо започаткування та провадження освітньої діяльності у процедурі ліцензування у сфері вищої освіти. Також на основі власного досвіду узагальнено окремі дискусійні питання щодо кадрового забезпечення, виявлені під час проходження процедури ліцензування освітньої діяльності у сфері вищої освіти.
ІНТЕРПРЕТАЦІЯ ПОЕТИЧНИХ ТЕКСТІВ ЯК ЗАСІБ РОЗВИТКУ ЛІНГВОСОЦІОКУЛЬТУРНОЇ КОМПЕТЕНТНОСТІ СТУДЕНТІВ
Authors: KARBASHEVSKA Oksana , BILIANSKA Iryna
Published: September 2019

У статті представлено загальний зміст елективної навчальної дисципліни «Інтерпретація поетичного тексту». Описано такі теми курсу, як «поезія у колі красних мистецтв», «образність і символізм у поезії», «англо-шотландська фольклорна балада». Зазначено, що художні твори мають високий естетичний, виховний і розвивальний потенціал, а інтерпретація закладеної у них інформації стимулює аналітичне мислення студентів, розвиває їх художньо-естетичне сприйняття, збагачує духовний світ. Зроблено висновок про те, що сформувати лінгвосоціокультурну компетентність студентів можливо засобами тлумачення поетичних творів, оскільки опосередкована міжкультурна комунікація зумовлює розширення кругозору студентів лінгвосоціокультурними знаннями, які є необхідними для досягнення порозуміння у ситуаціях міжкультурного спілкування та розвитку їх здатності до медіації в усній чи письмовій формі. Наголошено, що інтерпретація поетичних творів сприятиме вихованню любові та інтересу до естетики художнього слова, фаху філолога.
ДУХОВНО-МОРАЛЬНІ ЦІННОСТІ У ПРОФЕСІЙНОМУ СТАНОВЛЕННІ ОСОБИСТОСТІ МАЙБУТНЬОГО СОЦІАЛЬНОГО ПРАЦІВНИКА
Authors: SABAT Nadia , SABAT Natalia
Published: September 2019

У статті розкрито роль духовно-моральних цінностей у професійному становленні особистості майбутнього соціального працівника. Охарактеризовано соціальну роботу як особливий вид діяльності, що базується на принципах гуманізму, віри у власні сили людини, визнання права кожного на самовизначення, створення рівних можливостей. Доведено, що у практичній діяльності соціального працівника разом з професійними знаннями вагому роль відіграють особистісно-моральні якості: чесність, совість, об’єктивність, справедливість, тактовність, пильність і спостережливість, толерантність, витримка і самовладання, доброта, любов до людей, терпіння, комунікабельність, оптимізм; розкрито сутність основних з них. Простежено зв’язок духовно-моральних цінностей соціального працівника з його ціннісними орієнтаціями. Охарактеризовано засоби формування духовно-моральних цінностей у процесі фахової підготовки майбутнього соціального працівника.
THE DEVELOPMENT OF TECHNICAL EDUCATION OF NADDNIPRYANSHCHYNA IN THE FIRST TWENTY YEARS OF THE XX CENTURY
Authors: CHUMAK Mykola
Published: September 2019

The subject of the article is focused on the analysis of the peculiarities of the development of technical education in the areas of the Dnieper region under the influence of historical milestones of the first half of the twentieth century.

The basis of the influence of scientific and technological progress of the European states on the trajectory of development of the national education of the studied period is systematized.

It was noted that historical events in the territory of Ukraine that affected all spheres of society's life (in particular, socio-economic, political, cultural and educational) had a significant influence on socio-cultural "crystallization" of domestic technical education.

On the basis of the author's generalizations, the socio-cultural progress of the educational branch was reflected, which was possible due to: the progressiveness of educational initiatives, the diversification of didactic tools, the growing authority of progressive and intelligent circles in the international arena, and the high effectiveness of research developments.
Visualization and Quantification of Transposon Activity inCaenorhabditis elegansRNAi Pathway Mutants
Authors: Wallis Dylan C , Nguyen Dieu An H , Uebel Celja J , Phillips Carolyn M
Published: September 2019

RNA silencing pathways play critical roles in maintaining quiescence of transposons in germ cells to promote genome integrity. However the precise mechanism by which different types of transposons are recognized by these pathways is not fully understood. Furthermore, the location in the germline where this transposition occurs after disruption of transposon silencing was previously unknown. Here we utilize the spatial and temporal organization of the Caenorhabditis elegans germline to demonstrate that transposition of DNA transposons in RNA silencing pathway mutants occur in all stages of adult germ cells. We further demonstrate that the double-strand breaks generated by transposons can restore homologous recombination in a mutant defective for the generation of meiosis-specific double-strand breaks. Finally, we detected clear differences in transposase expression and transposon excision between distinct branches of the RNA silencing pathway, emphasizing that there are multiple mechanisms by which transposons can be recognized and routed for small-RNA-mediated silencing.
Congenital Syphilis Misdiagnosed as Suspected Nonaccidental Trauma
Authors: Jacobs Kimberley , Vu David M. , Mony Vidya , Sofos Elvera , Buzi Nadav
Published: September 2019

Congenital syphilis (CS) is a preventable infection, yet the incidence has surged to the highest rates in 20 years. Because 50% of live-born infants with CS are asymptomatic at birth, there is an increasing likelihood that pediatric providers will encounter older infants whose diagnoses were missed at birth, emphasizing the importance of timely prenatal screening and treatment. We present one such case of an infant admitted twice at 3 and 4 months of age with long bone fractures and suspected nonaccidental trauma. On her second presentation, several additional symptoms prompted evaluation for and eventual diagnosis of CS. In this case, it is demonstrated that an isolated long bone fracture can be a first presentation of CS, with other classic findings possibly appearing later. Pediatric providers should be familiar with the varied presentations of CS in older children, including the radiographic findings that we describe. The rising rates of CS reveal deficiencies in our current strategy to prevent CS and, thus, we recommend reconsideration of universal syphilis screening in the third trimester and at delivery, with timely treatment to prevent CS during pregnancy.
Statistical analysis of breast cancer data in a 3 years period (2016-2018) in Republic of North Macedonia and the Eastern region
Authors: Jihe Zhu, Blagica Arsovska,Kristina Kozovska*
Published: September 2019

Breast cancer is on the first place of malignant disease in women. By mortality it is4th most common and the incidence is constantly increasing in the world, in NorthMacedonia as well. Unfortunately, the exact number for cancer patients in NorthMacedonia is not known, but it is estimated that there are about 800 to 1 000 patientsper year. Stress is a serious risk factor and with most of the cancer patients in theanamnesis it is found that they were exposed to extreme stress. After the Bosnian warin the 90s, there was a sudden incidence of breast cancer. The rate of healing in theearly A1 stadium is from 98 to 100%. The problem in North Macedonia is that thescreening it’s not performed often, which causes the disease to be diagnosed in thelater stages. Most common is adenocarcinoma. In North Macedonia of all malignantneoplasms in women, breast cancer is first in mortality. Breast cancer mostly affectswomen aged 55 to 64 years at the level of the North Macedonia and the Easternregion. Compared to previous years, every year the number of breast cancer patientsis increasing, which means that the incidence of cancer is increasing. Work plansshould be directed to: health education of the population, education of women forproper and regular breast self-examination, education for regular screening for bothwomen and the general practitioners who should support and educate the populationon regular screening exams, as well as programs designed to support women who arebeing treated for breast cancer.Key words: breast cancer–oncology–analysis
A gyermekpszichodráma módszere Magyarországon
Authors: Szebeni Viola
Published: September 2019

Az írásom elméleti háttere a Kende B. Hanna által oktatott gyermekpszichodráma. Ennek a módszernek egyik alappillére a morenói pszichodráma. Részletesen taglalom, melyek azok a technikák, amelyek módosulnak a bemutatott módszerben, melyek a gyermekpszichodráma sajátos koordinátái. Áttekintő tanulmányom célja az elmúlt öt év adatainak az ismertetése: hány ilyen jellegű csoport működött a jelenlegi munkahelyemen, hány gyerek játszott a csoportokban, milyen korúak a gyerekek és problematikájukat tekintve, milyen tartalmakat lelhetünk fel. Fontosnak tartom a csoportok bemutatásakor azok sajátosságainak a megismertetését: korcsoportokra lebontva, valamint külön hangsúlyozva a különleges csoportok szerveződésekor megismert jellegzetességeket. Ilyen csoport a kamasz csoport. A Nemzetközi Gyermek- és Serdülő pszichodráma Konferencia, Közös nyelv – szimbolikus játék (Budapest, 2018. szeptember 28-30.; Kende Hanna Gyermekpszichodráma Egyesület szervezésében) során megfogalmazódott az Alfons Aichingerrel való együtt gondolkodás és együtt játszás során annak szükségessége, hogy minél szélesebb körben ismertessük a Magyarországon (is) játszott gyermekpszichodrámát, mert nagy a nemzetközi érdeklődés a Kende B. Hanna által oktatott módszer iránt. Ebben a tanulmányban néhány, több konferencián már bemutatott, kamaszokkal jól játszható, gyermekpszichodráma technikát szeretnék részletesen leírni és közkinccsé tenni. A módszer elsajátítása és alkalmazása a tanácsadási kompetenciával jól összeegyeztethető, többen vannak a módszerben képződött tanácsadó szakpszichológusok, akik a különböző korú gyermekcsoportokkal való foglalkozások során újításokkal, kreatív ötletekkel gazdagítják a gyermekpszichodrámát. Az innovációk szakmai körökben, rendszerint bemutatásra kerülnek. Nemzetközi együttműködés is fémjelzi az eddigiek során a technikák népszerűsítését. A gyermekpszichodráma terjedését illetően beszédesek azok az adatok, amelyek arról adnak számot, hogy egyre többen képződnek a módszerben, egyre több gyermekpszichodráma csoport működik az országban. Jelzem a hiányterületeket, főként a kamasz csoportok hiányát. Gyakran szakambulanciák működnek csoportterápiás ellátás nélkül. Feltárom az erőforrásokat, azokat a fórumokat, ahol megjelenhet a gyermekpszichodráma, bemutathatjuk technikáinkat, és azt is feltérképezem, ahol ennek még nincs tere. Célom a Kende B. Hanna által megteremtett és évtizedek óta oktatott módszer minél szélesebb körben való terjesztése, valamint olyan, kamaszokkal jól játszható technikák leírása, amelyek a gyakorlatban már használtak, beváltak, népszerűsítésre várnak.
Context Vectors are Reflections of Word Vectors in Half the Dimensions
Authors: Assylbekov Zhenisbek , Takhanov Rustem
Published: September 2019

This paper takes a step towards theoretical analysis of the relationship between word embeddings and context embeddings in models such as word2vec. We start from basic probabilistic assumptions on the nature of word vectors, context vectors, and text generation. These assumptions are supported either empirically or theoretically by the existing literature. Next, we show that under these assumptions the widely-used word-word PMI matrix is approximately a random symmetric Gaussian ensemble. This, in turn, implies that context vectors are reflections of word vectors in approximately half the dimensions. As a direct application of our result, we suggest a theoretically grounded way of tying weights in the SGNS model.
Perspectives on integrated water resource management and its relevance in understanding the water-energy-climate change nexus in South Africa
Authors: Mathetsa Steven Matome , Simatele Mulala Danny , Rampedi Isaac T. , Gericke Gerhard
Published: September 2019

It is increasingly acknowledged that the water-energy-climate change (WECC) nexus is one of the synergies that pose a significant risk to achievement of sustainable development goals (SDGs), specifically numbers six, seven and thirteen. There are suggestions that climate change outcomes such as increased temperature and drought episodes have implications for water availability, which in turn affects energy production in countries dependent on hydropower, pump-storage or coal-generated electricity, including South Africa. This development therefore calls for improved understanding of how to effectively manage the challenges that arise from this nexus, to mitigate the impacts it may have on achieving the associated SDGs. This study, which is based on an in-depth appraisal of existing developments, assessed the potential of the integrated water resource management framework in understanding the WECC nexus and its implications for South Africa’s sustainable development endeavours, particularly in the context of water resource management and utilisation. The study revealed South Africa’s lack of integrated, effective, and efficient institutions and policy framework to comprehensively manage the challenges emanating from this nexus. It identified an urgent need to develop systems and processes through which South Africa can handle the challenges as well as capture the benefits that may be obtained from this nexus.
Improving accuracy of wind resource assessment through feedback loops of operational performance data: A South African case study
Authors: Pullinger D. , Ali A. , Zhang M. , Hill N. , Crutchley T.
Published: September 2019

This study addresses two key objectives using operational performance data from most of the Round 1 wind farms connected to the grid in South Africa: benchmarking of wind farm performance and validation of the pre-construction energy yield assessments. These wind farms were found to perform in line with internationally reported levels of wind farm availability, with a mean energy-based availability of 97.8% during the first two years of operation. The pre-construction yield assessments used for financing in 2012 were found to over-predict project yield (P50) by 4.9%. This was consistent with other validation studies for Europe and North America. It was also noted that all projects exceed the pre-construction P90 estimate. The reasons for this discrepancy were identified, with the largest cause of error being wind flow and wake-modelling errors. Following a reassessment using up to date methodologies from 2018, the mean bias in pre-construction predictions was 1.4%.
Theoretical evaluation of valeraldehyde
Authors: Aziz Muhammad , Anwar Muhammad , Iqbal Shazia
Published: September 2019

The aim of this study was to compute the theoretical (software-based) spectroscopic properties of valeraldehyde as a member of the aldehyde family. The structural, thermochemical, electrical and spectroscopic properties of valeraldehyde were investigated using a quantum calculation approach. The infrared, ultraviolet-visible, Raman, and vibrational self-consistent field calculations and thermochemistry were calculated using the computational software GAMESS (General Atomic and Molecular Electronic Structure System) and the nuclear magnetic resonance predictions were calculated. The calculated energy gap between the lowest unoccupied molecular orbital (LUMO) and the highest occupied molecular orbital (HOMO) was 164.892.eV, which means valeraldehyde is a poor electrical conductor. The band gap is a non-neglected parameter for optical material. Results of the current computational analysis are useful to predict even a complex aldehyde precursor.
Significance:

The computational strategy used successfully here could also be useful for investigation of other aldehyde polymers.
A male-specific association between AGTR1 hypermethylation and coronary heart disease
Authors: Li Xiaojing , Wu Nan , Ji Huihui , Huang Yi , Hu Haochang , Li Jiyi , Mi Siyu , Duan Shiwei , Chen Xiaomin
Published: September 2019

The AGTR1 gene encodes angiotensin II receptor type 1, which is involved in cardiovascular diseases such as coronary heart disease (CHD). In the current study, we analyzed AGTR1 methylation level in a Han Chinese population by SYBR green-based quantitative methylation-specific PCR (qMSP). We collected blood samples from 761 CHD patients and 398 non-CHD controls at the Ningbo First Hospital. A data mining analysis was also performed to explore the association between AGTR1 methylation and AGTR1 gene expression, using datasets from the cBioPortal for Cancer Genomics and the Gene Expression Omnibus (GEO) database. Our results showed a significantly higher percentage of methylated reference (PMR) of AGTR1 in male CHD patients compared with male non-CHD controls (median PMR: 2.12% vs. 0.59%, p = 0.037). The data mining analysis showed that AGTR1 expression was significantly increased in human hepatoma HepG2 cells treated with the demethylation agent 5-aza-2'-deoxycytidine (fold = 3.12, p = 0.009). Further data mining analysis using the cholangiocarcinoma (TCGA, PanCancer Atlas) data indicated an inverse association between AGTR1 methylation and AGTR1 expression (r = -0.595, p = 1.29E-04). Overall, our results suggest that AGTR1 methylation is involved in the regulation of AGTR1 gene expression and that AGTR1 hypermethylation is associated with CHD in males. These findings may provide new clues about the pathogenesis of CHD.
The Method of League Analysis and Its Application in Comparing Global University Rankings and Russia’s University Performance Monitoring
Authors: Navodnov Vladimir , Motova Galina , Ryzhakova Olga
Published: September 2019

A new technique called Method of Analysis of Leagues (MethALeague) is proposed for comparing performance of higher education institutions measured by different assessment methods. The MethALeague uses the convolution operations from the theory of small-group decision making to create aggregate charts of university leagues based on the performance indicators obtained with different assessment techniques. Specifically, researchers are given the opportunity to bring widely divergent university performance indicators into unified assessment charts and carry out comparative analysis of different assessment approaches. The MethALeague was applied successfully to compare the performance indicators of the Project 5–100 universities reflected in three major global rankings, Academic Ranking of World Universities, QS World University Rankings, and Times Higher Education World University Rankings. A formalized concept of “world ranking” proposed in the article makes it possible to visualize the performance dynamics of Russia’s top universities and compare it to that of the top universities in other countries (United States, Great Britain, Australia, Germany, and China). Suggestions are made on using a modified version of the MethALeague at the national level to analyze the results of university performance monitoring and compare them to the universities’ global ranking positions. The method described in the article could be applied by educational authorities, researchers and higher education institutions to determine the frameworks of strategic development, both for specific universities and for Russia’s higher education system as a whole.
Psychological Well‐being in First‐ to Fifth‐Graders in the Context of Contemporary Social Situation of Development
Authors: Andreeva Alla , Moskvitina Olga
Published: September 2019

Psychological well-being of children in elementary school and during the transition to middle school is analyzed in the sociocultural context of the post-industrial society from the perspective that Russian psychology has on the social situation of development, its objective and subjective components, and its influence on school students’ educational outcomes and mental health. Level of aspiration, self-esteem and age satisfaction serve as integral indicators of students’ psychological well-being in this study, providing the basis for judging whether the social situation of development meets children’s age-specific needs. The method of comparative-historical research allows observing the dynamics of a child’s psychological life as a function of the social situation of development. It is shown that the age structure of both self-esteem and the level of aspiration in contemporary first to fifth-graders differs dramatically from that of their age-mates observed in studies of the last quarter of the 20th century, while age satisfaction has remained positive throughout the age period analyzed. Age crises adequate to the current social situation of development are found to bring down all the analyzed parameters of school students’ psychological well-being in Grade 4, which then rebound in Grade 5. The findings illustrate psychological well-being of contemporary school students in the context of the drastically changing social situation of development of the post-industrial society. Some gender differences have been observed in psychological readiness for middle school. The temporal structure of age satisfaction shows that girls prefer retaining their familiar social position in the teacher–student system, while boys experience the end of elementary school as a crisis of relationship that cannot foster their personal development anymore.
Age Peculiarities of Taking Initiative in Learning among Preschool Children
Authors: Klopotova Ekaterina , Yaglovskaya Elena
Published: September 2019

The article presents the results of an experimental study designed to identify the age peculiarities of taking initiative in learning among preschool children. Empirical data was obtained through non-participant observation of a teacher-guided group of children performing various productive tasks. A total of 480 preschoolers aged between 3 and 7 years were observed. Since teacher-guided peer learning prevails in preschool classrooms, we assume that child initiative could be determined as behaviors directed at co-participants in such learning. In this study, children’s initiative during interaction with adults and peers is defined as questions and suggestions that children raise in connection to the learning process, instigated by the need to coordinate joint actions. Analysis of the empirical data obtained allows determining the age dynamics and age-specific characteristics of preschoolers taking initiative while interacting with teachers. The number of self-initiated statements made by children is found to decrease and change in both direction and content throughout the preschool years.
Do School Social Studies Textbooks Need to Be Changed?
Authors: Chernobay Elena , Tuchkova Daria
Published: September 2019

Expected learning outcomes have changed following the adoption of the new Federal State Educational Standards of General Education. New organizational forms, teaching methods and tools are required to achieve the new learning outcomes, which affects functionality of conventional learning aids, school textbooks in particular. New interrelation mechanisms are being developed between the textbook and the other components of learning environment, transforming the textbook from the “communicator of ready-to-consume knowledge” into a “navigator for independent learning”. Under such circumstances, it is important to evaluate teachers’ attitudes towards the textbooks used, their perception of the changing role of textbooks in the learning process, and their satisfaction with textbook content, namely the methodological apparatus and its potential for achieving the new learning outcomes.

This article presents the results of a survey assessing school teachers’ perceptions of the system of learning tasks in some widely assigned social studies textbooks from the series edited by Leonid Bogolyubov, Anatoly Nikitin and Tatyana Nikitina, Gennady Bordovsky, and Yevgeniya Korolkova. The survey covered thirteen regions of the Russian Federation: Moscow Oblast, Voronezh, Tambov, Bryansk, Tver, Smolensk, Omsk, Krasnoyarsk, Rostov-on Don, Volgograd, Kazan, Nizhny Novgorod, and Saransk. The interview questionnaire included six themed modules: target audience profile analysis, teachers’ usage of different textbooks, the role of social studies textbooks in the learning process, textbook influence on the achievement of the new learning outcomes (formation of key 21st century competencies), teachers’ assessment of teaching guidebooks, and availability of social studies teaching packages in schools.

The article only explores the findings obtained for one questionnaire module, which explored how the methodological apparatus of social theory textbooks affected the creation of conditions for achieving metadisciplinary learning outcomes by school students, and offers recommendations on improving this apparatus.
The Catalogues of Textbooks for Secondary Schools of the Ministry of Public Education: On the Issue of Their Introduction (1830s – 1860s)
Authors: Pashkova Tatiana , Kameneva Ekaterina , Karasev Egor , Kutsevalov Nikita , Russkova Darya
Published: September 2019

The article is devoted to the study of the prerequisites and historical context of the emergence of a special type of official documentation of the Ministry of Public Education of the Russian Empire — catalogues of textbooks for secondary schools. The lists of study guides and manuals approved by the Ministry have become an important control instrument of the teaching of school subjects. Their content and structure were drawn up gradually from about the 1830s. An important stage in the process of reviewing and cataloging textbooks has been reached in 1865, when the first complete catalogue appeared, based on new rules.
How “Different School” Will Change the World. Review of the book: Murashev A. Different School. Where Normal People Come From
Authors: Lyubzhin Aleksey
Published: September 2019

The article speculates on the concept of “different school”, as illustrated by Alexander Murashev through the example of certain teachers, schools, school networks and systems that he studied by means of personal visits and face-to-face interviews with employees and students. The school model proposed by the author could take its small but rightful place in a schooling system that offers a choice of education patterns. “Different school” is a good option for highly sensitive children who shrink from facing the harsh social reality of regular schools and have limited ambitions and capabilities. However, as the only schooling system available, or even as a regular one, this model would have huge unwanted effects.