bluuebunny/crossref_metadata_2025 huggingface dataset:
SURVIVAL OF BACTERIA IN A SIMULATION OF SURROUNDING SURFACES OF CONSTRUCTIONS FOR SALT THERAPY
Authors: Kuznetsova Marina V. , Mammaeva M. G. , Barannikov V. G. , Kirichenko L. V.
Published: December 2019

Introduction. Ground constructions for salt therapy, which differ in the composition of minerals and in the modification of therapeutic surfaces, are actively used in Russia and abroad. The abiotic surfaces of these devices are susceptible to microbial contamination, the sources of which are the upper respiratory tract, the skin of patients and medical staff. The aim of the work is to assess the viability of microorganisms on abiotic surfaces identical to the material for the manufacture of salt physiotherapy constructions. Material and methods. 6 and 24 hours after application to abiotic surfaces with different relief there was evaluated the survival rate of reference gram-positive and gram-negative cultures of microorganisms and isolated ones from salt rooms. Viable cells were determined by the method of decimal dilutions in terms of the number of colonies-forming units (CFU). Results. It was found that bacterial cells can preserve at the halite and various surfaces of sylvinite for at least 24 hours. The viability of microorganisms was independent of the ratio of minerals (halite/sylvin) in the samples. The structure of the surface of sylvinite: the largest number of microorganisms was retained on crushed sylvinite (7.98E+02 ± 1.62E+03 CFU/ml was a significant factor for the survival of bacteria. Despite a great survival of staphylococci in comparison with gram-negative opportunistic pathogenic bacteria on all the surfaces studied, no significant differences between the groups were detected. In this case, bacteria isolated from salt structures were more resistant to salt load due to adaptive modification of microorganisms, including increasing the hydrophobicity of the cell wall, increasing their ability to survive. Bacteria grown on a solid agar medium proved to be more tolerant of the conditions of osmotic stress. Conclusion. The obtained data confirm the dependence of the adaptive mechanisms on the environmental conditions and the initial physiological state of cells. The results of studies on the survival of bacteria on salt surfaces of various types indicate their resistance to high concentrations of salts, which raises the question of special methods for treating fences of salt therapy structures.
Social experience of personality: an interdisciplinary categorical analysis
Authors: Pakhomov Ilya
Published: December 2019

We present a detailed analysis of the “social experience” concept from the point of view of philosophy, sociology, psychology and pedagogy. When considering social experience as an in-tegral concept, we carry out a separate analytical interpretation of the “experience” and “socialization” categories in the context of various scientific disciplines. The analysis of the designated concepts from the point of view of philosophy contains a historical digression that reveals the position of the phenomena studied in different philosophical schools. Sociology is considered as a source of the concept of “socialization” in its contemporary meaning. Psychology is considered as a discipline in which the study of human experience and interaction with it occupies a central place. Socialization is considered in the context of pedagogy as a science with its own unique specificity focusing on work with the educational process and its subjects: we analyze the basic pedagogical concepts of understanding socialization as a process of mastering social experience, and variative interpretations of this concept in scientific and pedagogical sources are considered. As a result of the analysis, we conclude that social experience should be understood as the experience of human participation in joint activities, which determines the level of knowledge and skills, as well as understanding of life in general. We also reveal the position of this phenomenon in a contemporary pedagogy.
Career Development of Indonesian National Police: The Case Study Analysis of Police Grand Comissioner Rank
Authors: Hari Kuncoro Mustafa , Tunas Billy , Wibowo
Published: December 2019

It was important for Indonesian National Police organizations to be able to managed their human resources through good management by giving employees or members the opportunity to advance. Human resources in one organization had an important role of Indonesian National Police experiences a surplus of members with the position of Police Grand Commissioner. As of the beginning of 2019, this institution had around 1,400 members serving as middle officers. Most of these officers did not get outside structural positions. The development system of the right police career pattern was able to provide direction for individual police officers to developed themselves. The purposed of this research was to analyzed case studies related to the career development of the Police Grand Commissioner ranked that took place at the Institution of Indonesian National Police. This research used a qualitative approach with a case study method. This study concluded that career development was an police's efforts to achieve a career plan. In this case, there were organizational efforts in the form of programs and activities to assisted the career development of Police Grand Commissioner personnel. Another important thing was related to education and training provided to Police Grand Commissioner personnel must be in accordance with the requirements needed, so that the quality improvement of Police Grand Commissioner personnel would be truly fulfilled and aimed to developing police competencies and careers in accordanced with the needs and challenges of Grand Commissioner Police personnel performance.
La crisis de Tarteso y el problema del siglo V a.C. en el ámbito geográfico turdetano
Authors: FERRER ALBELDA EDUARDO , GARCÍA FERNÁNDEZ FRANCISCO J.
Published: December 2019

La crisis del siglo VI a.C. originó transformaciones, como el fin de la economía colonial y de la aristocracia orientalizante, precipitadas por conflictos internos interpretados como la expresión de movimientos contra la población fenicia y la aristocracia local. El nuevo panorama se caracteriza por unas bases sociopolíticas y económicas diferentes que han dejado huella en el registro arqueológico, más por sus ausencias (necrópolis, santuarios, artesanía de lujo) que por la evidencia arqueológica. Así mismo, el siglo V a.C. ha sido definido como un doble fenómeno de transformación y continuidad: transformación en los fundamentos políticos de la coexistencia social –decadencia de la aristocracia gentilicia y emergencia de los valores cívicos– y la consolidación de la ciudad-estado, y continuidad en la estructura de los territorios, aunque fue entonces cuando empezaron a definirse las “fronteras” de las más importantes ciudades, como Carmo.
El marmor en los fora de la provincia Baetica
Authors: MARFIL VÁZQUEZ FRANCISCO
Published: December 2019

El estudio de los distintos elementos marmóreos conservados y adscritos a los foros de la Baetica ha permitido la jerarquización de los componentes del paisaje arquitectónico público de sus ciudades. Un ordenamiento que vendrá determinado por el uso de mármoles de distinta procedencia dependiendo de factores como la pieza que se pretendía elaborar, su ubicación dentro del escenario forense, la dignitas de la ciudad, el poder económico de sus élites urbanas o la posible conexión entre dicha comunidad y el emperador. La llegada al poder de Augusto supondrá una verdadera revolución que abarcará todos los aspectos políticos, religiosos, sociales y culturales; una nueva era en la cual la arquitectura pública se pondrá al servicio del princeps y que en el territorio bético vivirá una segunda y última renovación estilística tras la ascensión de la dinastía Ulpia-Aelia.
El mosaico de las Termas Marítimas de Baelo Claudia: contexto, iconografía, arqueometría y restauración
Authors: PASCUAL SÁNCHEZ MARÍA ÁNGELES , BERNAL-CASASOLA DARÍO , DOMÍNGUEZ-BELLA SALVADOR , DURANTE MACÍAS ANA , EXPÓSITO ÁLVAREZ JOSÉ ÁNGEL , DÍAZ RODRÍGUEZ JOSÉ J. , MILLÁN SALGADO MARÍA LUISA
Published: December 2019

En este trabajo se presenta un estudio interdisciplinar del mosaico de las Termas Marítimas de Baelo Claudia, activas entre el s. II e inicios del IV d.C., aunando la problemática del contexto arqueológico de hallazgo (contexto secundario fechado en el s. VI d.C. aparecido en el interior de una bañera de agua fría), su análisis iconográfico (motivos marinos), la caracterización arqueométrica de sus teselas y las tareas de restauración de los fragmentos de mosaico, el cual puede considerarse un hallazgo excepcional en esta zona del conventus Gaditanus.
Psychometric Properties of the Self-Report Version of the Strengths and Difficulties Questionnaire in Iranian young Adolescents
Authors: shirinbayan peymaneh , Salavati Mahyar , Soleimani Farin , Saeedi Ahmad , Hemmati Sahel , Asghari-Jafarabadi Mohammad , Vameghi Roshanak
Published: December 2019

Background: The Strengths and Difﬁculties Questionnaire (SDQ), is a brief behavioral screening tool, widely used for assessing mental health problems in adolescents. The present study evaluated the psychometric properties of the Persian version of the self-report SDQ (P-SDQ) in Iranian young adolescents. Methods: In this cross-sectional study, 244 young adolescents participated from 4 different geographic regions of Tehran and completed the questionnaire. The reliability of P-SDQ scores was determined by Cronbach’s alpha coefficient. The face validity was assessed qualitatively. The construct validity of the test scores was evaluated by Confirmatory Factor Analysis (CFA). Results: The internal consistency of P-SDQ scores was confirmed for all subscales (alpha values ranged from 0.62 to 0.69) and the whole questionnaire (alpha=0.80), except for the peer relationship problems subscale scores (alpha=0.45). CFA supported a five-factor structure in the first order (relating the items to the subscales), except for the peer relationship problems subscale, and a one-factor structure in the second order (relating the subscales to the whole SDQ), except for the peer relationship problems subscale. In addition, the results of CFA revealed that the peer relationship problems subscale was showed; item-scale relations were significant in all subscales, except for the peer relationship problems subscale. Conclusions: The obtained results supported t desirable reliability and validity for all P-SDQ subscale scores and the overall score, except for the peer relationship problems subscale. It seems that the peer relationship problems subscale of the P-SDQ requires further modifications prior to being considered as appropriate for assessing mental health in Iranian young adolescents.
IMP-2005: an injury mortality prediction according to the Abbreviated Injury Scale 2005
Authors: Wang Muding , Qiu Wusi , Zeng Yunji , Fan Wenhui , Wang Xueming , Shen Yi
Published: December 2019

Background: It has been 45 years since the injury severity score (ISS) was first introduced. The method is flawed in traumatic death prediction but still widely used. Based on the abbreviated injury scale 1998 (AIS_98), there is a relatively more accurate trauma scoring method that assesses the injury mortality prediction (IMP) and trauma mortality prediction model (TMPM) with the regression model. Currently, AIS 2005 (AIS_05) is widely used around the world for trauma scores. This article assesses whether the IMP-2005, an AIS_05 based model, is better than the ISS in predicting trauma results. Methods: Retrospective cohort study is based on the data of 1,239,404 injured patients in the National Trauma Data Bank hospitalized from 2012 to 2014. We established an injury mortality prediction (IMP-2005) model using AIS trauma codes (version 2005) and compared its performance with that of ISS by examining area under the receiver operating characteristic (ROC) curve, the Hosmer-Lemeshow (HL) statistic, and the Akaike information criterion.Results: IMP-2005 behaves significantly both better discrimination (ROCIMP-2005, 0.904; 95% confidence interval (CI), 0.900 to 0.909 and ROCISS, 0.844; 95% CI, 0.839 to 0.850) and calibration (HLIMP-2005, 15.2; 95% CI, 8.5 to20.2 and HLISS, 221; 95% CI, 167 to 268) compared with ISS. Both models showed changes after the extension of gender, age, GCS, mechanism of injury, and mechanical ventilator, but the expansion of IMP-2005 still dominated ISS in every performance.Conclusions: The IMP-2005 provides far improvement in discrimination and calibration compared with the ISS and accurate predictions of mortality. Therefore, we believe that this is a new and feasible scoring method of trauma research and should replace the ISS.
Outcomes of operative versus non-operative interventions on rectus abdominis diastasis: a combination of a retrospective analysis and a systematic review
Authors: yuan sue , Li Yunxia , Li Qi , Fan Lu , Zhou Jie
Published: December 2019

Background There is no current consensus on the treatment of Rectus abdominis diastasis (RAD). This study aimed to assess the recurrence rates and adverse events after operative or non-operative intervention.Methods We performed a retrospective study and a systematic review. Patients with a diagnosis of RAD who underwent the mesh placement procedure were eligible. Data were collected from The Research Patient Data Registry. Then, a systematic literature search of Pubmed, Embase, and The Cochrane Library databases was performed. A modified Downs and Black checklist for randomized and non-randomized studies of healthcare interventions (DB) was used to evaluate the methodological quality of the studies.Results Data of 82 patients was collected. The 5-year cumulative incidence of recurrence of abdominal hernia was high (females 37.0% vs males 43.4%, P = 0.557). Of 3908 citations, 27 studies describing 2,372 patients were included into the systematic review. In non-operative group, seven studies (25.93%) with a total of 603 subjects reported no patient relapsed after a follow-up of 12 months; a 40% recurrence rate was reported after a follow-up of 5 years in one study, the adverse events associated with operation mainly included seroma (5.13%), a sensibility disorder of the abdominal skin (2.26%), and minor scarring (1.56%). Muscle strength training, such as training of the pelvic floor muscles, abdominal muscles, rectus abdominis, internal/external oblique, or transverse abdominal muscles, was performed in all included non-surgery studies, neither adverse events nor recurrence was reported.Conclusion Operative intervention may be effective at restoring the functions of the rectus muscles and at improving the stability of abdominal wall in the short-term, while non-operative intervention has a limited effect, especially for those RAD combined with hernia.
Safety and efficacy of intravenous oxycodone in geriatric patients undergoing general anesthesia for ophthalmic surgeries:a randomized controlled trial
Authors: Li Shuangshuang , Yao Dongdong , Hu Xiao , Li Wenxian , Tan Fang
Published: December 2019

BackgroundThe present study aimed to compare the safety and efficacy of intravenous oxycodone with fentanyl in geriatric patients undergoing general anesthesia for ophthalmic surgeries.Methods107 geriatric patients (age 65-79 years old) with the ASA physical status 1 or 2 undergoing general anesthesia for glaucoma or retina surgeries between May 2016 and November 2017 were divided into three groups: Group O1, Group O2, and Group F. After exclusion, 105 patients were included for the final analysis, with 35 patients in each group. Oxycodone (0.1 mg/kg in Group O1, or 0.2 mg/kg in Group O2) or fentanyl (2 mcg/kg in Group F) was administered intravenously during induction of general anesthesia. Patient demographics, surgical time and anesthesia time, perioperative hemodynamic parameters and requirement of vasoactive medication, postoperative pain and requirement of rescue analgesics, postoperative sedation level and recovery time, and perioperative complications were recorded.ResultsPatients in Group O1 experienced less clinically significant hypotension compared to either Group F or Group O2. Consistently, patients in Group O1 required less intraoperative vasoactive medication (ephedrine) than those in Group F. The postoperative pain on extubation was more severe and more patients required rescue analgesia in Group F compared to Group O2, but not Group O1. The recovery time was longer and sedation level was higher in Group O2 than Group F or O1. The incidence of hypoxia during postoperative recovery was higher in Group O2 than Group F or O1.ConclusionOxycodone at 0.1mg/kg can be a safe and effective application for geriatric patients undergoing general anesthesia for ophthalmic surgeries, with adequate pain control and less side effects.
Clinical Safety and Efficacy of Nasogastric Tube placement after Gastrectomy
Authors: Wu Zhouqiao , Wang Qi , Shi Jinyao , Hou Shiyang , Shan Fei , Li Shuangxi , Zhang Yan , Li Ziyu , Ji Jiafu
Published: December 2019

Background: Enhanced recovery after surgery (ERAS) program has become the main trend in gastrointestinal surgery. The aim of this study is to investigate factors influencing the decision-making of nasogastric tube (NGT) placement and its safety and efficacy in clinical practice. Methods: We analyzed our prospectively maintained database including 287 patients underwent elective gastrectomy in our department from January 1 to December 31, 2017. All cases were divided into two groups, namely, the non-nasogastric tube group and the nasogastric tube group. Logistic regression was used to analyze the factors that affect the decision of nasogastric tube placement, and propensity score matching (PSM) was later applied to balance those factors for the analysis of the safety outcomes between the groups. Results: Multivariate analysis showed that resection range (p=0.004, proximal gastrectomy: OR=4.555, 95%CI=1.392-14.905, p=0.016; total gastrectomy: OR=1.990, 95%CI=1.205-3.287, p=0.009) was the only independent risk factors of nasogastric tube placement. NGT was omitted in the majority (58.8%) of distal gastrectomy, but only in 42.5% and 25% in total and proximal gastrectomy. After PSM, we found no significant differences between patients with or without NGT in postoperative hospital stay, time to first flatus and defecation, time to fluid and semi-fluid diet, rate of reinsertion, or hospitalization expenditure (p>0.05 respectively). The incidence of postoperative complications in the two groups were 21.7% and 23.5% respectively (p=0.753), and the incidence of major complications were 7.0% and 9.6% (p=0.472). Conclusions: The decision-making of NGT placement is mainly influenced by the resection range. Omitting NGT is a safe approach in all types of gastrectomy but was not able to enhance the recovery in our practice.
Evaluation of Nine Canadian Retail Consumer Potting Mixes for Growing Container Plants
Authors: Clark Mary Jane , Zheng Youbin
Published: December 2019

Commercially available Canadian retail potting mixes were evaluated for physical and chemical properties, as well as for plant performance of petunia (Petunia ×hybrida ‘Storm Pink’), tomato (Solanum lycopersicum ‘Better Bush’), and zonal geranium (Pelargonium ×hortorum ‘Savannah Red’) plants grown outdoors at the Vineland Research and Innovation Center in the Niagara Peninsula in Ontario, Canada. Chemical properties, but no physical properties, resulted in significant correlation with plant growth index, overall appearance, and yield (i.e., flower, fruit, or inflorescence number for petunia, tomato, and zonal geranium, respectively). The performance of all species was best when initial potting mix pH and electrical conductivity (EC) values were in the ranges of 5.20 to 6.17 and 2.76 to 4.33 mS·cm−1, respectively. The physical properties of the container capacity, total porosity, air space, and bulk density were acceptable for all plants in this study and ranged from 71% to 80%, 78% to 96%, 8% to 20%, and 0.08 to 0.22 g·cm−3, respectively. The minimum concentrations of the initial nitrate (NO3−), ammonium (NH4+), phosphorus (P), and potassium that were acceptable were 104.4, 61.3, 47.9, and 150.5 ppm for petunia and 96.8, 61.3, 51.7, and 143.3 ppm for tomato, respectively. The minimum concentration of NO3− that was acceptable was 66.1 ppm for zonal geranium. Overall appearance at 4, 8, and 10 weeks after transplanting was correlated with initial potting mix EC, NO3−, and calcium for all species, with pH, NH4+, and P for petunia, with P for tomato at all time points, and with P for zonal geranium after 10 weeks. Although it is difficult to discern how each nutrient impacts plant performance, this study indicated that it is essential to have a balanced and adequate supply of nutrients in consumer potting mixes. The ability of a potting mix to maintain an appropriate pH for the duration of the growing season may prevent nutrient deficiency symptoms, especially for pH-sensitive species like petunia. This study is the first to provide a benchmark of currently available retail potting mixes for Canadian consumers.
Presentación Lámpsakos número 22
Authors: Torres Pardo Ingrid Durley
Published: December 2019

Lámpsakos, en su número 22, abre su publicación con una editorial relacionada con la “Transformación digital en instituciones de educación superior” [1]. Un tema de interés y actualidad, escrito por uno de los expertos más reconocidos en el ámbito de la academia. Esta editorial es la antesala del valioso contenido que la publicación presenta a nuestros lectores en esta nueva edición.
La responsabilidad internacional de los estados
Authors: Barbero Natalia
Published: December 2019

Los Estados, por solo ser miembros de la Organización de Naciones Unidas —en virtud de las obligaciones derivadas de su Carta—, pero más aún por sus compromisos convencionales, tienen el deber de cumplir con normas internacionales y responder ante la comunidad internacional. En particular, los Estados tienen el deber de respetar y garantizar los derechos humanos previstos en cada tratado, lo cual incluye la obligación de no violación y de prevención, investigación y sanción en caso de incumplimiento. Queda incluido también en este marco el deber de tutela judicial efectiva, y queda prohibido, a su vez, invocar disposiciones de Derecho interno que impidan el cumplimiento de las obligaciones asumidas. Solo así se da un marco integral a la protección de los derechos humanos.
Justicia transicional en Ecuador: la justicia más allá de la justicia
Authors: Vargas Yangua Jeny
Published: December 2019

Este texto presenta una reflexión del proceso de justicia transicional que emprendió Ecuador desde el año 2007 con la creación de la Comisión de la Verdad, desde una mirada académica en sintonía con las acciones encaminadas a reivindicar el derecho a la verdad, la justicia y la reparación de las víctimas documentadas en el informe realizado por esta comisión “Sin Verdad no hay Justicia.”
Preliminary study on stimulatory and inhibitory effects of aldehydes from the green leaf volatiles family on beneficial and pathogenic bacteria from the intestine
Authors: GOKER GAMZE , DEMIRTAS AHU
Published: December 2019

The balance between beneficial and pathogenic bacteria in the intestine has a great importance in terms of gut physiology and immunity. The aim of the study was to investigate the stimulatory and inhibitory effects of aldehydes from the green leaf volatiles family (trans-2-hexenal, cis-3-hexenal, trans-2-nonenal, and trans-2- decenal) on beneficial (Bifidobacterium bifidum, Bifidobacterium longum subsp. infantis, Lactobacillus acidophilus, and Lactobacillus casei) and pathogenic bacteria (Fusobacterium nucleatum subsp. nucleatum, Clostridium perfringens, Staphylococcus aureus subsp. aureus, Escherichia coli, and Salmonella enterica subsp. enterica serovar Typhimurium) from the intestine. The growth of B. bifidum was stimulated by trans-2-hexenal and trans-2-decenal at 3.9-250 μg/mL, by cis-3-hexenal at 15.6 and 31.3 μg/mL, and by trans-2-nonenal at a dose of 3.9-500 μg/mL (p < 0.05). Trans-2-decenal also moderately stimulated L. acidophilus at concentrations of 31.3 and 62.5 (p < 0.05). Trans-2-hexenal, cis-3-hexenal, and trans-2-nonenal did not inhibit beneficial intestinal bacteria, with the exception of B. infantis. Trans-2-decenal was the most effective aldehyde on pathogens, with growth-inhibitory effect on C. perfringens, F. nucleatum, and S. aureus at the concentration of 500 μg/mL. Trans-2-decenal also protected beneficial bacteria at the dose at which it inhibited pathogenic ones. All the used aldehydes at a concentration of 500 μg/mL inhibited the growth of F. nucleatum as one of the agents of colorectal cancer. Among the pathogens, E. coli and S. Typhimurium were resistant to all aldehydes while S. aureus was inhibited only by trans-2-decenal. In conclusion, the use of aldehydes from the green leaf volatiles family might have beneficial effects on gut health by regulating beneficial bacteria and inhibiting pathogenic bacteria.
PERFIL DE URGÊNCIAS ODONTOLÓGICAS NO ESTADO DA PARAÍBA: UMA ANÁLISE DO PMAQ-AB
Authors: Wanderley Gomes Freire Deborah Ellen , Cavalcanti Yuri Wanderley , Freire Aldelany Ramalho , Gomes de Lucena Edson Hilan
Published: December 2019

Objetivo: Avaliar os fatores associados à procura por atendimentos de urgência odontológica na Atenção Primária à Saúde. Metodologia: Foi realizado estudo transversal analítico, a partir dos microdados do 2° ciclo de avaliação externa do Programa de Melhoria do Acesso e da Qualidade da Atenção Básica (PMAQ-AB) no estado da Paraíba. Dados de relato de casos de urgência odontológica (n=1.531) e da procura por atendimento após episódio de urgência (n=824) foram avaliados segundo características sociodemográficas (sexo, idade, estado civil, cor da pele, analfabetismo, renda e cadastro no bolsa família). Os dados foram analisados por meio de regressão logística multivariada, pela qual foram obtidas as medidas de razão de chances (OR) e intervalo de confiança (IC95%), considerando-se p<0,05. Resultados: Indivíduos que informaram não saber ler apresentaram maior chance (OR=1,430, IC95%= 1,113-1,836) de relatar alguma urgência odontológica. As variáveis idade e renda compuseram o modelo ajustado de regressão, porém sem significância (p>0,05). Entre os indivíduos que relataram urgência odontológica, 57,9% informaram procurar atendimento odontológico após o episódio de urgência. A procura por atendimento odontológico em casos de urgência se deu preferencialmente por indivíduos com maior idade (OR=1,014, IC95%= 1,003-1,026). Conclusões: As urgências odontológicas foram mais frequentes entre indivíduos que não sabem ler, o que reflete uma iniquidade em saúde. A maior procura dos idosos por serviços odontológicos nos casos de urgência revela o acesso preferencial dessa população via SUS.
MODEL PEMBELAJARAN ASAM BASA BERBASIS SCS (SCIENCE PROCESS SKILLS) MELALUI KEGIATAN LABORATORIUM SEBAGAI WAHANA PENDIDIKAN SAINS SISWA MTS
Authors: Hidayah Malikhatul
Published: December 2019

Tujuan  penelitian  ini  adalah  untuk    memperkenal- kan dan mengetahui efektivitas Model Pembelajaran SCS ( Science Process Skills ) melalui kegiatan Laboratorium Sebagai Wahana Pendidikan Sains yang cocok bagi siswa MTs agar meningkatkan: penguasaan konsep kimia, ke- mampuan berpikir kreatif, dan keterampilan  sains siswa. Metode yang digunakan adalah metode penelitian kelas, dan difokuskan pada pokok bahasan asam basa. Penelitian ini dilakukan di salah satu MTs Negeri di kota Semarang dengan subyek sebanyak 40 siswa kelas III. Instrumen yang digunakan dalam penelitian ini meliputi model pembelaja- ran, soal-soal tes, pedoman wawancara, pedoman obser- vasi dan angket, sedang LKS digunakan pada saat kegiatan laboratorium. Dalam model pembelajaran dikembangkan empat jenis konsep yaitu konsep kongkret, konsep yang menyatakan sifat, konsep yang melibatkan penggambaran simbol, dan konsep berdasarkan prinsip. Model pembela- jaran ini dapat meningkatkan pemahaman konsep pada setiap kelompok kemampuan siswa, mengembangkan ke- mampuan berpikir kreatif dengan hasil tertinggi pada as- pek membangun konsep di atas pengetahuan yang telah ada pada diri siswa dan terendah pada aspek memilih hal- hal yang mungkin tidak relevan, serta keterampilan sains mengatasi kurangnya waktu pembelajaran, bagian-bagian pembelajaran tertentu dapat dilaksanakan di luar jam ke- las.
Copper and Neurotoxicity in Autism Spectrum Disorder
Authors: Santos Gesivaldo , Borges Julita M.P. , Avila-Rodriguez Marco , Gaíno Silvana B. , Barreto George E. , Rúbio Érika P. , Aguiar Rosane M. , Galembeck Eduardo , Bromochenkel Cattiúscia B. , de Oliveira Djalma M.
Published: December 2019

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Free radicals (FR) act on living organisms and present unpaired electrons in the molecular orbitals of oxygen or nitrogen species. They are classified as redox reactions and account for a wide range of processes in biological systems. Genetic and environmental factors may alter the levels of FR in the cell, leading to deleterious consequences such as membrane lipid peroxidation, protein nitration, enzyme, carbohydrate and DNA damage, ultimately resulting in premature aging and a pro-inflammatory microenvironment as observed in Alzheimer’s disease (AD) and autism spectrum disorder (ASD). O2 radical ability to act as a Lewis base and to form a complex with metal transition such as iron and copper (Lewis acids) leads to biomolecules oxidation at physiological pH, thus increasing the possibility of injury and oxidative damage in biological tissues. In this review, we discuss the role of metals, like copper, and the amyloid precursor protein (APP) derivative (s-APP-alpha) as an antioxidant and a possible adjuvant in the treatment of some autistic spectrum disorder symptoms (ASD).
El momento óptimo para invertir en una empresa de la agroindustria del café\\ (Una Aplicación de la Teoría de las Opciones Reales)
Authors: Hernández Álvarez Zenón , Ramos Álvarez María De Jesús
Published: December 2019

La alta volatilidad del precio real del café en el mercado internacional hace que la valoración tradicional sea insuficiente para valorar proyectos de inversión en la agroindustria de café. El presente trabajo muestra como cuantificar e incorporar la incertidumbre en la valoración para determinar el momento más oportuno en el cual una empresa de café invertiría para comercializar su café como café oro verde y tostado en el mercado nacional. La teoría de las opciones reales a través del modelo del momento de inversión óptima permite decidir si invertir o no mediante un valor crítico. Para la empresa social en estudio, se encontró que la inversión se debe llevar acabo puesto que, el valor del proyecto ( ) es superior al valor crítico ( ). Si la empresa vendiera solo café oro verde ( ) su decisión sería no invertir ( ). Cuando la volatilidad es alta la inversión debe ser diferida. Al tomar en cuenta la volatilidad de la inversión se podría estimar su “verdadero valor” permitiendo a la directiva tomar mejores decisiones.
Doctors online – when the personal and professional collide: a proposed model to cope with the status quo (Preprint)
Authors: Shepherd Rajendra
Published: December 2019

UNSTRUCTURED

The online environment has created a need to define online medical professionalism. Its current definition is complicated by advice in tension with public expectations.

This paper surveys the advice and offers a model that postulates the online space as having a personal-professional duality. The model accommodates the concept of phases: totally ‘private’, totally ‘professional’ or ‘private-professional’ shifted by societal pressures.

I argue that the model works along two dimensions – that of Information to Advice (I-A) and personal disclosure (PD) – and that a doctor should consider whether her post is likely to be seen as ‘general’ or ‘expert’ to better predict public acceptability.
Mobile Apps for Mental Health Issues: Meta-Review of Meta-Analyses (Preprint)
Authors: Lecomte Tania , Potvin Stéphane , Corbière Marc , Guay Stéphane , Samson Crystal , Cloutier Briana , Francoeur Audrey , Pennou Antoine , Khazaal Yasser
Published: December 2019

BACKGROUND

Mental health apps have great potential to help people needing support to cope with distress or specific symptoms. In fact, there is an exponential increase in the number of mental health apps available on the internet, with less than 5% being actually studied.

OBJECTIVE

This study aimed to assess the quality of the available evidence regarding the use of mental health apps and to summarize the results obtained so far.

METHODS

Systematic reviews and meta-analyses were searched, specifically for mobile apps on mental health issues or symptoms, and rated using the Grading of Recommendations Assessment, Development and Evaluation system.

RESULTS

A total of 7 meta-analyses were carefully reviewed and rated. Although some meta-analyses looked at any mental health issue and analyzed the data together, these studies were of poorer quality and did not offer strong empirical support for the apps. Studies focusing specifically on anxiety symptoms or depressive symptoms were of moderate to high quality and generally had small to medium effect sizes. Similarly, the effects of apps on stress and quality of life tended to offer small to medium effects and were of moderate to high quality. Studies looking at stand-alone apps had smaller effect sizes but better empirical quality than studies looking at apps with guidance. The studies that included follow-ups mostly found a sustained impact of the app at an 11-week follow-up.

CONCLUSIONS

This meta-review revealed that apps for anxiety and depression hold great promise with clear clinical advantages, either as stand-alone self-management or as adjunctive treatments. More meta-analyses and more quality studies are needed to recommend apps for other mental health issues or for specific populations.
The limited role and risky profile of Rituximab in nephritis associated with Henoch-Schönlein purpura
Authors: El-Reshaid Kamel , Al-Bader Shaima
Published: December 2019

Adult-onset IgA vasculitis or Henoch-Schönlein purpura (HSP) is a systemic vasculitis characterized by IgA1-dominant deposits.  The symptoms include cutaneous purpura, ankle arthritis, enteritis and nephritis.  HSP nephritis (HSPN) can be severe and refractory to corticosteroids with/without immunosuppressive agents.  The concept of depletion of antibody producing B cell with Rituximab is appealing despite the uncertainity of HSP pathogenesis.  In the present case report; we describe our experience with Rituximab treatment in a patient with this disease.  Our patient had different triggering factors for her relapses and lately Rituximab itself.  Review of the literature indicates that autoantibodies to Gd-IgA1 did not decrease with Rituximab therapy and others indicated an inherited predisposition for higher levels in patients with progressive disease.  Our findings confirm the limited role and risky profile of Rituximab in treatment of HSP. 

Keywords: HSP, IgA, Rituximab, vasculitis.
Impact of a Discussion Series on Race on Medical Student Perceptions of Bias in Health Care
Authors: Bright H. Reeve , Nokes Keith
Published: December 2019

Background and Objectives: Racial bias in health care is increasingly recognized as a factor in health inequities, yet there is limited research regarding medical school education around race and racism and its impact on medical students. The purpose of this study was to understand attitudes of medical students on race and racism in health care and to study the impact of participation in a voluntary structured program on race and racism.
Methods: First-year medical students had the opportunity to participate in a series of discussions (10 hours total) on race and racism. A 10-question survey addressing comfort, knowledge, and the adequacy of education on race and racism was sent to all first-year medical students (n=61/180, response rate 34%), and was administered to series participants (n=23/25, response rate 92%) in a pre/post format.
Results: Participant and nonparticipant attitudes were similar at baseline, with the exception that participants were less likely to feel that the medical school curriculum provided adequate education on race and racism, and reported higher levels of knowledge around these issues. Following the discussion series, participants showed significant changes regarding knowledge and awareness, as well as comfort level discussing race and racism.
Conclusions: Participants were more likely than nonparticipants to think that the curriculum should include more discussion on race and racism. Postparticipation analysis demonstrated significant increases in comfort level, knowledge, and awareness in discussion of race and racism.
O TECIDO COLORIDO NA DANÇA-TEATRO DE PINA E BARBA: Uma Dramaturgia Plural de Subjetivação
Authors: Piva Bruno Leal
Published: December 2019

O presente artigo tem o intuito de relacionar a composição dramatúrgica de Pina Bausch e Eugênio Barba em sua dança-teatro, a partir do envolvimento dos atores-dançarinos na criação cênica, levando em consideração suas experiências pessoais e suas participações na construção de uma narrativa plural, envolvidas por suas subjetividades ou subpartituras, num processo contínuo de subjetivação.
A DANÇA DOS OUTROS
Authors: Luciane Ramos-Silva
Published: December 2019

Entendendo movimento como prática social, cultural e política, percebemos que nestes tempos sombrios algumas danças têm possibilitado o surgimento de poderosos atos criativos. A partir da observação de um conjunto de artistas negras e negros, que criam na contramão da engrenagem compressora de desejos, discutimos, à luz de alguns intelectuais basilares para a luta antirracista e a crítica cultural, fundamentos e formas de escritas de si que desconstroem estigmas coloniais, inserem a discussão crítica da diferença e possibilitam uma abordagem das identidades não como “pautas”, mas como reelaboração de existências e disputa de narrativas.
Lugares de escuta e de acolhimento nas pesquisas sobre sertanidades
Authors: Veiga Ana Maria , Pereira Vasconcelos Vânia Nara
Published: December 2019

Este texto se propõe a mapear o surgimento de um campo de estudos que vem se consolidando a partir de pesquisas individuais e pontuais que tratam das relações entre gênero, história das mulheres e sertanidades. Em 2018 foi criado o grupo de pesquisa ProjetAH,reunindo professoras e estudantes de universidades diversas que atuam no campo acadêmico e/ou em movimentos relacionados com a temática. O grupo passou a se constituir como um “lugar de escuta” de histórias e da produção de memórias de mulheres e da população LGBTQI+. O campo de estudos sobre gênero, mulheres e sertanidades entra em diálogo com as teorias pós/decoloniais, assim como incorpora o conceito de interseccionalidades, dando visibilidade a sujeitas/os ausentes de uma historiografia que tradicionalmente não considera sujeitos em situação de margem, que vivem em territorialidades sertanejas.
Željezničke prometnice u obalnom pojasu Nezavisne Države Hrvatske do kapitulacije Kraljevine Italije
Authors: Barić Nikica
Published: December 2019

U članku se, znatnim dijelom na temelju novih arhivskih izvora, prikazuje stanje željezničkih prometnica u obalnom pojasu Nezavisne Države Hrvatske. Talijanska vojska preuzela je početkom rujna 1941. upravu u tom pojasu. Članak prati stanje na tim prometnicima do talijanske kapitulacije u rujnu 1943. godine. Kroz ovo istraživanje može
se doći do određenih novih spoznaja o odnosima Nezavisne Države Hrvatske i Kraljevine Italije, ali i do novih spoznaja kada je riječ o prometnim vezama, u konkretnom slučaju željezničkim, koje su u ratnim okolnostima povezivale krajeve uz jadransku obalu sa zaleđem, odnosno Zagrebom i drugim krajevima sjeverno od rijeke Save.
Revisiting simulation functions via interpolative contractions
Authors: Karapinar Erdal
Published: December 2019

In this paper, introduce the notion of an interpolative Hardy-Rogers type
Z-contraction and we revisit the renowned Hardy-Rogers contraction in the
framework of interpolation. We investigate the existence of fixed points for
such mappings in the context of metric spaces and list immediate consequences that covers some existing results in the literature.
Peran Teacher Autonomy Support terhadap Engagement Siswa melalui Pemenuhan Kebutuhan Psikologis Dasar
Authors: Rohinsa Meilani , Cahyadi Surya , Djunaidi Achmad , Iskandar Zulrizka
Published: December 2019

Penelitian ini bertujuan untuk menginvestigasi apakah pemenuhan kebutuhan psikologis dasar memediasi pengaruh teacher autonomy support terhadap engagement. Responden dalam penelitian ini 213 siswa SMA (Wanita=126, 59.2%; M = 87, 40.8%). Usia responden antara 15-18 tahun dengan mean 15.41 (SD=0.53). Alat ukur yang digunakan adalah kuesioner Autonomy support, Feeling I Have  dan Engagement. Data dianalisis dengan uji regresi berganda. Hasil penelitian ini menunjukkan pemenuhan kebutuhan psikologis dasar memediasi pengaruh teacher autonomy support terhadap engagement. Implikasi dari temuan ini bahwa guru harus menyadari bahwa setiap siswa memiliki kebutuhan psikologis dasr yang dapat dipenuhi oleh perlakuan guru berupa autonomy support dan hal ini akan membentuk engagement siswa terhadapa aktivitas belajar di kelas.Keyword Teacher autonomy support, Pemenuhan kebutuhan psikologis dasar, Engagement
Be Mindful, Less Stress: Studi Tentang Mindful Parenting Dan Stres Pengasuhan Pada Ibu Dari Anak Usia Middle Childhood Di Jakarta
Authors: Gani Izmiyah Afaf , Kumalasari Dewi
Published: December 2019

Mengasuh anak usia sekolah dasar merupakan salah satu tugas ibu yang penuh tantangan sehingga jika ibu tidak mampu mengatasi tantangan ini, maka ibu rentan mengalami stres pengasuhan. Penelitian ini bertujuan untuk menguji peran mindful parenting terhadap stres pengasuhan pada ibu yang memiliki anak usia sekolah dasar. Penelitian menggunakan pendekatan penelitian kuantitatif dengan desain asosiatif. Partisipan penelitian berjumlah 110 ibu berusia 28-46 tahun. Teknik pengambilan data yang digunakan adalah sampling insidental. Alat ukur Parental Stress Scale (PSS) memiliki reliabilitas 0,906 dan digunakan untuk mengukur stres pengasuhan kemudian alat ukur Mindfulness in Parenting Scale (MIPQ) memiliki reliabilitas 0,818 digunakan untuk mengukur mindful parenting. Hipotesa penelitian diuji dengan menggunakan teknik statistik Uji Regresi Linear Sederhana. Hasil uji hipotesa menunjukkan bahwa terdapat peran signifikan mindful parenting terhadap stres pengasuhan. Hasil penelitian ini dapat dijadikan sebagai suatu rujukan untuk mengatasi stres pengasuhan yang dialami oleh ibu yang memiliki anak usia sekolah dasar melalui edukasi masyarakat mengenai peran mindful parenting terhadap stres pengasuhan.
Hubungan Intensitas Penggunaan Smartphone Dengan Disiplin Belajar Siswa Kelas X SMA 2 Pariaman
Authors: Septiani Hanifa , Sylvia Ike
Published: December 2019

Penelitian ini bertujuan untuk melihat hubungan intensitas penggunaan Smartphone dengan disiplin belajar siswa kelas X SMA N 2 Pariaman. Maka jenis penelitian ini adalah penelitian ex-post facto yang bersifat korelasional. Teknik pengambilan sampel yang digunakan dalam penelitian ini proporsional random sampling, Jumlah siswa kelas X SMA N 2 Pariaman berjumlah 354. Penelitian ini menggunakan tingkat kesalahan sebesar 10% sehingga sampel yang diperlukan yaitu 78 orang. Penelitian ini penggunakan dua macam variabel yaitu: 1) variabel bebas: intensitas penggunaan smartphone (X) 2) variabel terikat: disiplin belajar (Y). Pengumpulan data untuk variabel intensitas penggunaan smartphone dan disiplin belajar menggunakan metode angket dengan skala Likert. Keabsahan data diperoleh melalui uji validitas dan reliabelitas. Teknik analisis data yang digunakan adalah analisis deskriptif untuk melihat (mean,mediam,modus, dan standar deviasi). Teknik analisis data yang digunakan antara lain kategoris persentase, uji normalitas, analisis untuk uji hipotesis menggunakan rumus korelasi product moment.
Обратный меридиональный циклодиализ ab interno в лечении открытоугольной глаукомы — предварительные результаты
Authors: Кумар В. , Фролов М. А. , Душина Г. Н. , Шрадка А. С. , Беззаботнов А. И. , Абу Заалан К. А.
Published: December 2019

Увеосклеральный путь оттока внутриглазной жидкости (ВГЖ) представляет большой интерес в хирургическом лечении глаукомы. Суть операции циклодиализа заключается в создании прямого сообщения между передней камерой (ПК) глаза и супрахориоидальным пространством (СХП), главным звеном увеосклерального пути оттока ВГЖ. Целью нашего исследования было оценить безопасность и эффективность обратного меридионального циклодиализа ab interno (ОМЦai) в снижении внутриглазного давления (ВГД) у пациентов с первичной открытоугольной глаукомой (ПОУГ) и рефрактерной глаукомой (РГ). У 14 пациентов с ПОУГ (11 мужчин и 3 женщины в возрасте 77,3 ± 7,8 лет) был проведен ОМЦai с помощью специально разработанного шпателя. Шпателем создавали циклодиализную щель шириной 2,0–2,5 мм и глубиной 6,0–6,5 мм. Критериями оценки успеха операции были динамика ВГД, потребность в дополнительной гипотензивной терапии и повторном хирургическом вмешательстве, а также наличие осложнений. Успех считали полным, если ВГД снижалось более чем на 20% и оставалось в переделах 6–21 мм рт. ст. без применения гипотензивных средств. Признанный успех связывали с потребностью в гипотензивной терапии. Лечение считали неудачным, если возникала необходимость в повторном хирургическом вмешательстве. Пациенты оставались под наблюдением не менее трех месяцев. Исходное ВГД и количество используемых гипотензивных препаратов составляли 22,0 ± 8,5 мм рт. ст. и 2,6 ± 0,9 соответственно. Через 3, 6, 12, 18 и 24 месяца после операции полный успех был достигнут в 64,3, 77,8, 55,6, 37,5 и 40% случаев соответственно, признанный — в 14,3, 22,2, 44,4, 50 и 60% случаев. Повторная операция потребовалась 4 пациентам. Причиной неудачи стала фиброзная облитерация циклодиализной щели. Было установлено, что ОМЦai безопасен и эффективен в снижении ВГД у пациентов с ПОУГ и РГ.
Development of state support tools for small innovative business
Authors: Barkovskaya Viktoria
Published: December 2019

The article analyzes the concept and main directions of small business in the Russian Federation. In the framework of innovation support directions, direct and indirect methods of stimulating the industry have been identified. The results of financing small businesses in 2018 are presented. The study reflects the features of the regulatory framework in the field of state regulation

of small innovative business. Some changes in fiscal policy since 2019 have been noted. The De-crees of the RF Government “Strategy for Small Enterprises in Russian Federation for the period up to 2030” and “Digital Economy of the Russian Federation” are the fundamental regulatory documents in the field of improving the support of small innovative businesses. Creating and operation of business incubators, coworking centers and cooperation with universities were highlighted as available forms of support. The experience of foreign countries testifies to the attention of the private sector as a source of support for small businesses. Foreign structures for promoting the development of small business innovative activities are presented, such as Small Business Financing Corporation in Japan, Federation of Industrial Research Associations in Germany, Technological Innovation Fund in Italy, National Agency for the Implementation of Research Results in France, etc. Based on the results of the analysis, principles and measures have been developed to improve the activities of state bodies in developing tools for state support of small innovation entrepreneurship. It is proposed to analyze the events in the context of three constituent elements: methodological, regulatory and functional resource blocks. The proposed system for developing state support tools for small innovative businesses covers all levels of government: federal, regional and municipal.