bluuebunny/crossref_metadata_2025 huggingface dataset:
Digestion activator MegaBoost Rumen in feeding of highly productive cows
Authors:   Federal State Budgetary Educational Institution of Higher Education “Kostroma State Agricultural Academy”, Russia, Kostroma region, Kostroma district, Karavaevo, Baranova N. S. , Khoshtaria G. E. ,   Federal State Budgetary Educational Institution of Higher Education “Vologda State Dairy Farming Academy named after N. V. Vereshchagin”, Russia, Vologda, Molochnoye
Published: September 2024

Improvement of standardized feeding of cows with record milk yields is carried out by optimizing rumen digestion with the inclusion of effective feed additives in the rations. In the Vologda region and in the country as a whole herds of cows with a high genetic potential for productivity have been bred the implementation of which is impossible without improving their feeding by using eff ective feed products that contribute to the optimization of metabolic processes of digestion. The purpose of the work was to determine the eff ect of the digestion activator MegaBoost Rumen on the digestibility of nutrients in cows with a milk yield of 9000–10000 kg of milk on their daily milk yield, milk composition, and health status. Inclusion of two dosages of the biological product MegaBoost Rumen into the rations of highly productive cows during the transition period such as 50 g/head/day to the 1st experimental group and 100 g/head/ day to the 2nd experimental group, and from the 22nd to the 150th day of lactation 100 g/head/day to both experimental groups, had a positive eff ect on the palatability of feed mixtures, the digestibility of nutrients, including fi ber and nitrogen-free extractive substances. Higher retention of nutrients in cows when using the digestion activator caused an increase in milk yield by 7.9 and 10.9 % with a decrease in feed costs for production and maintaining high nutritional properties of milk. Normalization of metabolic processes in cows of the experimental groups was experimentally confi rmed by biochemical blood tests. Animal science and economic analysis of the results of scientifi c and economic experiment convincingly showed that the most acceptable dosage of the additive was that used in the 2nd experimental group ensuring an increase in the level of profitability of milk production in the fi rst half of lactation to 25.5 %.
Efficiency of use of land and feed resources to increase milk productivity of cows
Authors:   Kurgan State Agricultural Academy named after T. S. Maltsev – a branch of the Federal State Budgetary Educational Institution of Higher Education “Kurgan State University”, Russia, Kurgan region, Lesnikovo, Nazarchenko O. V. , Khairullina N. I. ,   Bashkir Research Institute of Agriculture is a separate structural unit of the Federal State Budgetary Scientifi c Institution “Ufa Federal Research Center of the Russian Academy of Sciences”, Russia, Republic of Bashkortostan, Ufa, Chanyshev I. O. ,   Bashkir Research Institute of Agriculture is a separate structural unit of the Federal State Budgetary Scientifi c Institution “Ufa Federal Research Center of the Russian Academy of Sciences”, Russia, Republic of Bashkortostan, Ufa, Sabitov M. T. ,   Bashkir Research Institute of Agriculture is a separate structural unit of the Federal State Budgetary Scientifi c Institution “Ufa Federal Research Center of the Russian Academy of Sciences”, Russia, Republic of Bashkortostan, Ufa, Shamsutdinov D. Kh. ,   Bashkir Research Institute of Agriculture is a separate structural unit of the Federal State Budgetary Scientifi c Institution “Ufa Federal Research Center of the Russian Academy of Sciences”, Russia, Republic of Bashkortostan, Ufa
Published: September 2024

The purpose of the research was to study the effi ciency of using land and feed resources to increase milk productivity of cows. Research on the quality of soil and prepared silage was carried out under the conditions of JSC Agrofi rma Pravda, Sterlibashevsky district, Republic of Bashkortostan. The quality of silage was studied on cowsof Simmental dreed, which were selected based on the principle of pairs-analogues, taking into account age and physiological condition. Three groups of cows were formed per 10 heads in each group. In the experiment, cows of the 1st control group have received silage mass without preservatives, the 2nd experimental group received silage with the addition of the bio-preservative Lactobifadolin a dose 150 g/t into the silage mass and the 3rd experimental group received silage with the bio-preservative Lactoenterolin the dose 150 g/t. It was found as a result that the content of nutrients in the soils of the farm increases. Thus, the humus content increased by 1.4 abs.% over 5 years, mobile phosphorus by 13.5 %, exchangeable potassium by 4.6 %. A uniform situation was observed for other elements. Feeding lactating cows with silage prepared with bio-preservatives contributed to a more favorable course of mineral, fat and protein metabolism, and accordingly to the complete absorption of nutrients in the digestion process. Cows in the experimental groups had higher milk productivity during the fi rst 100 days of lactation, and used biologically active substances to a better extent for the synthesis of milk components. The inclusion of bio-preservatives in silage made it possible to accelerate the fermentation process in the ensiled mass, reduce nutrient losses and increase its energy and protein value.
Use of bio-preservatives to increase the nutritional value of silage and haylage
Authors:   Federal State Budgetary Educational Institution of Higher Education «Saint-Petersburg State Agrarian University», Russia, Saint-Petersburg, Pushkin, Laptev G. Yu. , Bikonya S. N. ,   Federal State Budgetary Educational Institution of Higher Education «Saint-Petersburg State Agrarian University», Russia, Saint-Petersburg, Pushkin
Published: September 2024

It is important when preparing bulky feed to use various types of bio-preservatives that help reduce nutrient losses and improve the organoleptic and quality properties of preserved feed. The purpose of the research was to study the use of bio-preservatives to increase the nutritional value of silage and haylage. During the research the Hattori method was used to determine the physiological state of bacteria in bio-preservatives; NGS sequencing of silage prepared with the Biotrof® 2+ starter was carried out; an analysis of the expression of genes synthesizing L-lactate dehydrogenase and D-lactate dehydrogenase by the microbiota of silage laid with the multi-strain biopreservative Biotrof® 2+ was carried out. Under production conditions, tests of the new bio-preservative for silage Biotrof®-AC were carried out and recommendations for its use were given. It has been established that the use of silage prepared with the starter Biotrof® 2+ in the rations of lactating cows was cost-effective. The revenue from the use of the liquid bio-preservative Biotrof® 2+ was higher compared to the use of the dry preparation Best-Sil dry and the dry preparation Silo Feedtech® M20XCE by 2.3 and 5.6 %, respectively. The profi t received from the sale of milk in the group of cows fed silage with the starter Biotrof® 2+ was higher than in the groups fed silage with the fermentation starters Best-Sil dry and with Silo Feedtech® M20XCE by 4.8 and 12.0 %, respectively. The use of the fermentation starter culture Biotrof®2+ contributed to an increase in the level of profitability in the 1st group by 1.1 and 2.7 absolute% compared to the 2nd and 3rd groups.
Identitas Visual Karakter Animasi Sebagai Representasi Multikultural Labuan Bajo
Authors: Julianto I Nyoman Larry , Mudana I Gede , Putra Adnyana Yasa Gede Pasek , Sustiawati Ni Luh , Ardini Ni Wayan , Sumerjana Ketut , Andreani Ni Putu Elvian
Published: September 2024

The visual identity of the animated characters of the Bugis, Flores and Bima tribes in Labuan Bajo is a creative manifestation of the cultural diversity that characterizes the region. Through meticulous design, these characters become strong visual representations of the rich ethnic and cultural heritage that coexists. The use of local cultural symbols, colors, and motifs provide a deep introduction to the cultural identity of each tribe, while a modern twist on the design acknowledges the changing times without sacrificing respect for tradition. This abstract discusses how the visual identity of the animated characters creates a narrative of inclusiveness and acceptance of diversity, creating an image of Labuan Bajo as a place that blends in multicultural harmony. Overall, the animated characters become a window into the beauty and complexity of the region, and contribute positively to the image of Labuan Bajo as a fascinating multicultural destination.
Los ambientes de aprendizaje y su relación con las prácticas pedagógicas inclusivas
Authors: Villalba Cristian García , Prieto Margie Lisseth Marroquín , Resles Jennifer Paola Olivella
Published: September 2024

Esta investigación tiene como objetivo determinar el nivel de inclusión de las prácticas pedagógicas de los docentes de la Fundación Universitaria Monserrate y la Escuela Militar de Suboficiales “Sargento Inocencio Chincá” EMSUB y la correspondencia con los ambientes de aprendizaje, esto, aunado a la política de inclusión de ambas instituciones. Se toma como componente teórico la pedagogía crítica y se basa en la teoría de la educación inclusiva. Lo anterior, se sustenta desde una investigación cuantitativa formulada a partir de la aplicación de un cuestionario a los docentes de ambas universidades y la aprehensión de su nivel de inclusión. En lo que respecta, se encuentra que, los docentes responden a escenarios medianamente incluyentes y se reconoce en la investigación la aplicación de un ambiente de aprendizaje de tipo cooperativo.
Uso de Inteligência Artificial para interpretação de tomografias e raio x: comment crítica
Authors: Alves Sabrina Martins , Figueiredo Maria da Conceição Gonçalves de , Morão Bruno Felipe Fernandes , Silva Vithor Alves da , Aquino Mykaelle Rezende Almeida de , Prata Júnior José Rômulo Cavalcante , Landim José Marcondes Macedo , Sousa Danilo Ferreira de
Published: September 2024

Este estudo tem como objetivo realizar uma análise crítica sobre o uso da inteligência artificial na interpretação de tomografias e raios-X, avaliando suas potencialidades, limitações e desafios enfrentados na prática clínica. N Método: Foi realizada uma revisão da literatura para identificar estudos relevantes que investigam o uso de IA em imagens médicas. Foram considerados aspectos como algoritmos utilizados, conjuntos de dados, desempenho comparado com diagnóstico humano e aplicabilidade clínica. Além disso, foram analisadas as questões éticas, regulatórias e de segurança associadas ao uso da IA nesse contexto. Resultados: Os resultados destacam avanços significativos no desenvolvimento de algoritmos de IA para interpretação de imagens médicas, com desempenho comparável ou até superior ao diagnóstico humano em algumas condições. No entanto, ainda existem desafios importantes a serem superados, como a interpretação de casos complexos, a necessidade de conjuntos de dados representativos e diversificados, além de questões éticas relacionadas à responsabilidade e transparência dos algoritmos. Considerações Finais: O uso da inteligência artificial na interpretação de tomografias e raios-X apresenta um grande potencial para melhorar a precisão e eficiência do diagnóstico médico. No entanto, é fundamental abordar questões relacionadas à validação clínica, regulamentação e ética para garantir sua integração segura e eficaz na prática clínica.
Estudo da detecção de traços de composto modelo por espectroscopia SERRS e SERS utilizando nanopartículas de prata e ouro
Authors: Oliveira Arthur Antoniassi Ota de , Koenig Leandro , Batista Aline Domingues , Santana Henrique de
Published: September 2024

O trabalho teve como objetivo avaliar as melhores condições de amostragem para detecção de traços de composto modelo por meio da técnica Raman, através do emprego de soluções coloidais de prata e ouro. Os espectros de absorção UV-Vis demostraram que o coloide de prata não apresentou perda de propriedades óticas quando diluído em solução aquosa, embora foi verificado um alargamento nas bandas observadas nos espectros após a diluição em solução contendo 0,1 mol L-1 de KCl.  Foram realizados experimentos de espectroscopia Raman com o cristal violeta (CV) em diferentes concentrações e soluções, diluído nos coloides de prata. Foi observado que a excitação do espectro Raman próximo à transição eletrônica permitida da molécula causou o efeito Raman ressonante (RR), intensificando o sinal Raman mesmo em baixas concentrações da molécula, que se somou ao efeito SERS ocasionado pelas nanopartículas. Este efeito conjugado foi denominado de Espectroscopia Raman ressonante intensificação por superfície (SERRS). A detecção de traço do CV com o colóide de prata, por SERRS, foi favorecida na presença de KCl, demostrando que a relação entre a intensidade dos espectros Raman e a concentração de CV seguiu um modelo linear, proporcionando uma descrição simplificada da sensibilidade da curva. Entretanto, o coloide de ouro não apresentou mesmo comportamento, porém, viabiliza a detecção de traços do CV a baixas concentrações pelo efeito SERS. Esses experimentos demonstraram a estabilidade do coloide de prata em diferentes diluições e a eficácia da técnica SERRS para a intensificação do sinal Raman em baixas concentrações de CV.
Avaliação das alterações glicêmicas baseadas na hemoglobina glicada e glicemia média estimada em pacientes do Centro de Atendimento Comunitário do CEUB (CAC)
Authors: Pereira Anna Luiza Pompéia de Souza , Bittar Fadi Amado , Andrade Tania Cristina Santos
Published: September 2024

A diabetes mellitus (DM) é uma doença crônica não transmissível (DCNT) de grande importância mundial e de saúde pública que tem se tornado cada vez mais frequente e vem desencadeando diversas patologias secundárias e, consequentemente, aumentando o número de mortes dentro da população. Tal distúrbio possui algumas formas de diagnóstico, podendo ser através da glicemia de jejum (GJ), testes de sobrecarga glicêmica ou pela hemoglobina glicada (HbA1c). A hemoglobina glicada é formada a partir da ligação da glicose à hemoglobina dentro das hemácias e, com isso, é possível avaliar a glicemia de pacientes com até 4 meses de antecedência, através do cálculo da glicemia média estimada (GME). Esse método é considerado padrão ouro para controle da glicemia e tem grande relevância, precisão e facilidade de execução. O objetivo desse estudo foi calcular a glicemia média estimada de pacientes do Laboratório Escola do CEUB através da hemoglobina glicada e correlacionar com resultados da glicemia de jejum (GJ) para avaliar as alterações glicêmicas evidenciadas pelo resultado dos dois exames e verificar a possibilidade de avaliação glicêmica sem a necessidade do jejum para a coleta de material biológico. Para a análise estatística, foi utilizada a plataforma Bioestat 5.3 que comparou GJ com a GME através do teste T. Foi evidenciado que o descarte do jejum não é possível para os pacientes, apesar dos valores para glicemia de jejum igual ou acima de 126 g/dL ter apresentado valor de correlação um pouco mais expressivo, diferente dos resultados mostrados em outras comparações examinadas.
Integração de realidade aumentada no marketing digital 360: uma abordagem para engajamento de consumidores
Authors: Souza Felipe Thyago Tellini de , Marcon Gilberto Brandão , Antunes Neto Joaquim Maria Ferreira
Published: September 2024

Este estudo explora a integração da Realidade Aumentada (AR) como uma estratégia inovadora no contexto do Marketing Digital 360, com foco na potencialização do engajamento de consumidores. A AR oferece às marcas a capacidade de criar experiências interativas e imersivas, permitindo aos consumidores visualizar produtos virtualmente em seu ambiente real, experimentar serviços antes da compra e participar de narrativas envolventes. A abordagem integrada proposta destaca como a AR não apenas enriquece a experiência do usuário, mas também fortalece a conexão emocional com a marca, resultando em maior fidelidade. Também se discute a integração da AR com outras estratégias de marketing digital, como SEO, mídias sociais e e-mail marketing, destacando a importância de uma abordagem holística e coesa para maximizar o impacto e o retorno sobre o investimento. Por fim, são apresentadas perspectivas sobre as tendências emergentes da AR e suas potenciais evoluções, reforçando seu papel como uma ferramenta estratégica essencial para as marcas na era digital atual.
METHOD FOR PLACING SHOES PARTS TEMPLATES FOR THE ARK 1500 CUTTING COMPLEX WITH ASSESSMENT OF THE PERCENTAGE OF MATERIAL AREA USE
Authors: Tarasov Sergey D. , Staroverov Boris A. , Lapshin Valery V. , Levykin Mikhail P.
Published: September 2024

This article discusses the method of placing templates for shoe parts for the ARK 1500 cutting complex. The technique was developed to automate the operation of the ARK 1500 cutting complex and increase the percentage of use of the material being cut. The object of study in this article is the placement of shoe parts templates on a sheet of material. The subject of the research is methods for rational placement of templates and increasing the percentage of material used. The developed methodology is implemented in the form of a computer program. The article provides an example of using the technique of placing templates on part templates used in production.
METHODS OF WORKING WITH INTERNATIONAL INFORMATION OWN CORRESPONDENTS OF RUSSIAN TV CHANNELS
Authors: Mirimanov D. A. , Kalinina V. S.
Published: September 2024

With the development of international relations and the institution of diplomacy, world chronicles become key in television news programs and benefit the mass reader. As a result, of the last few changes, there has been a significant transformation in the meaning of international information: television companies and agencies have begun to actively cover events occurring in foreign countries. In our study, we analyzed the work methods of journalists from the central Russian television channels “Channel One,” “Russia-1,” and “NTV.” A detailed description was obtained through in-depth interviews with television reporters - Alexey Kruchinin, Sergey Iezuitov, Alexey Veselovsky, Alexander Gurnov. The article describes the activities of correspondents from the point of view of technical, everyday and cultural features; the difference in approaches to presenting international information is analyzed. The article for the first time demonstrates the systematic specificity of the approach in the work of its own correspondents, based on an analysis of their activities.
Assessing The Influence of Board of Commissioners, Audit Committees, and Company Scale on Business Performance
Authors: Lasmi Ni Wayan , P Komang Widhya Sedana Putra , Sukarnasih Desak Made
Published: September 2024

In this study, experts aimed to identify variables influencing organizational performance, focusing on the size of the audit committee and the composition of the board of commissioners as two indicators of corporate governance (GCG). These variables are crucial for achieving organizational goals and implementing effective GCG practices. The Board of Commissioners, working closely with the organization, oversees internal operations, with the Audit Committee assisting in fulfilling its responsibilities. The Audit Committee is responsible for financial reporting, internal auditing, and ensuring GCG compliance. Company size and performance are closely linked, with larger organizations often performing better in operational activities. This study investigates the impact of company size, the board of commissioners, and the audit committee on business performance. Utilizing data from annual financial reports of the food and beverage subsector for the years 2020-2022, sourced from the official IDX website, the study analyzed 99 samples using multiple regression analyses. The findings shed light on how organizational performance is influenced by company size, the audit committee's composition, and the board of commissioners.
Das atopische Ekzem – weit mehr als eine Hautkrankheit
Authors: Comte Krieger Emilie , del Río Sancho Sergio , Christen-Zaech Stéphanie
Published: September 2024

Das atopische Ekzem (AE) ist eine chronische Hautkrankheit, die durch Xerodermie, Juckreiz und wiederkehrende Entzündungsschübe gekennzeichnet ist. Pathophysiologisch liegen dem AE eine Beeinträchtigung der Hautbarriere, eine überschiessende Immunantwort sowie genetische und umweltbedingte Faktoren zugrunde.
AKTIVITAS ANTIRADIASI KRIM EKSTRAK METANOL BUNGA GUMITIR (TAGETES ERECTA)
Authors: Ekayanti Ni Wayan Sri , Wijaya Putu Austin Widyasari
Published: September 2024

Radiasi sinar matahari yang tinggi dapat mengaktifkan Reactive Oxygen Species yang berdampak buruk pada kesehatan tubuh dan dapat mempercepat terjadinya proses photoaging. Upaya pencegahan dapat dilakukan dengan penggunaan tabir surya berbahan dasar alami. Bunga gumitir sebagai produk lokal diketahui memiliki aktivitas antioksidan yang memiliki kandungan flavonoid, fenolik dan karotenoid.  Kebaruan dalam penelitian ini adalah aktivitas antiradiasi krim ekstrak bunga gumitir dengan konsentrasi yang berbeda. Tujuan dari penelitian ini untuk menganalisis aktivitas antiradiasi krim ekstrak metanol bunga gumitir. Metode yang digunakan adalah eksperimental dengan rancangan acak kelompok yang terdiri dari 5 kelompok perlakuan dengan konsentrasi ekstrak yang berbeda (0, 10%, 20%, 30%, 40%). Sampel diuji dengan metode in vitro dengan spektrofotometer UV-Vis, tiap 5 nm dari panjang gelombang 292,5– 372,5 nm. Hasil menunjukkan krim ekstrak metanol bunga gumitir 40% pada konsentrasi 1000 ppm memiliki nilai SPF dengan kategori perlindungan maksimal. Krim ekstrak bunga gumitir dengan konsentrasi 30% dan 40% memiliki kategori fast tanning terhadap UVB dan total block terhadap UVA. Kesimpulan penelitian ini menunjukkan krim ekstrak metanol bunga gumitir memiliki aktivitas antiradiasi.
Evaluating the Impact of Healthcare Access on Maternal and Child Mortality in a Rural Region of Myanmar
Authors: Kwee Than Phyu , Thet Hnin , Khaing Yaung Hlaing
Published: September 2024

This study evaluates the impact of healthcare access on maternal and child mortality rates in the rural region of Kayin State, Myanmar, where disparities in healthcare services significantly affect vulnerable populations. Utilizing a cross-sectional study design from February to July 2024, the research employs both quantitative and qualitative methodologies. Quantitative data is gathered from government health records and local healthcare facilities, including maternal and child mortality rates, healthcare facility availability, and healthcare worker distribution. Qualitative insights are obtained through semi-structured interviews with healthcare providers, mothers, and local stakeholders, focusing on barriers to healthcare access. The findings reveal alarming maternal mortality rates of 250 per 100,000 live births and child mortality rates of 80 per 1,000 live births in rural areas, compared to urban counterparts. Major barriers identified include geographic isolation, economic challenges, and cultural factors limiting healthcare utilization. This study underscores the urgent need for targeted interventions to improve healthcare access in rural communities. Future research should investigate longitudinal impacts of healthcare interventions and the effectiveness of health education programs to further understand and mitigate healthcare disparities in rural Myanmar.
Unveiling Antimicrobial Resistance Trends in Malaysia: A Comparative Study with Global Pattern
Authors: Ismail Andi Regina Acacia , Lisa Guymer , Diana Katharina , Vasso Nicola , Kylie Anna
Published: September 2024

This research explores the patterns of antimicrobial resistance (AMR) in Malaysia, with a focus on major bacterial strains such as MRSA, E. coli, Klebsiella, and Pseudomonas. Data from clinical microbiology laboratories in both public and private hospitals was collected using a cross-sectional, observational study design. Analysis of resistance rates indicated that MRSA showed a resistance rate of 45%, which was notably greater than the global standard of 30% (p < 0.01). Likewise, E. coli, Klebsiella, and Pseudomonas displayed resistance rates of 55%, 40%, and 35%, respectively. These results emphasize the increasing problem of AMR in Malaysia, especially in urban healthcare settings, where resistance rates were higher than in rural areas. In the future, researchers need to enhance AMR monitoring systems and encourage responsible use of antibiotics in Malaysia. Comparison with worldwide databases like WHO GLASS and CDDEP indicates that focused efforts in urban areas are needed to address the increasing resistance rates. This research highlights the need to tackle AMR promptly by collaborating among policymakers, healthcare providers, and public health institutions. Additional research is required to assess the efficiency of existing methods and discover innovative ways to address AMR within the area.
Development of Mobile Application for Accounting Subject
Authors: Hakim Azammullah Muhammad Akmal , Ahmad Zaki Nadia Akma , Manaf Abdi
Published: September 2024

This study aims to develop a mobile application called "On-Lejar" to assist Form 4 students in learning the Ledger (Lejar) topic in accounting. The application addresses the limited availability of online study aids for accounting, which has led to difficulties in mastering the Ledger topic. Traditional teaching methods, which often rely solely on direct instruction from teachers, can hinder student engagement and interest in accounting. By incorporating multimedia and information technology elements, the On-Lejar application seeks to enhance the learning experience for both students and educators. The Agile Model guided the application’s development, and functionality tests conducted with 10 respondents through questionnaires indicated high satisfaction with the app's overall performance, encouraging further learning and use. Additionally, the study highlights the role of Open Distance Learning (ODL) in ensuring continuity in education, especially during the COVID-19 pandemic. Educational applications, including the On-Lejar app, have become vital in facilitating home teaching and learning activities, promoting student engagement and flexible access to resources. Future recommendations include continuous innovation in educational applications to maintain user interest. Overall, the research underscores that engaging learning experiences can be achieved beyond the traditional classroom setting through well-developed mobile applications.
Annual Variations of PM10, PM2.5 and PM1.0 Fraction at an Urban Site in Ansan, Korea
Authors: Kim Pilho , Shin Su Hyun , Kim Chang Hyeok , Park Jong-Sung , Hwang Kyucheol , Kim Jong Bum , Park Jungmin , Kim Jeongho
Published: September 2024

This study examines particulate matter (PM) concentrations, specifically PM10, PM2.5, and PM1.0, at an urban site in Ansan, South Korea. Three BAM-1020 continuous monitors measured PM10, PM2.5, and PM1.0 hourly from January to December 2021, with data acquisition rates of 97.1%, 97.3%, and 93.4%, respectively. Average annual concentrations were 45.7±48.4 µg/m³ (PM10), 26.4±22.7 µg/m³ (PM2.5), and 18.5±14.5 µg/m³ (PM1.0). PM10 was 91% of the annual air quality standard, while PM2.5 exceeded this standard by 176%, indicating severe pollution. Statistical analyses using probability density function (PDF) and cumulative distribution function (CDF) showed 98.5% of data converged at 150 µg/m³ (PM10), 75 µg/m³ (PM2.5), and 50 µg/m³ (PM1.0), with the remaining 1.5% corresponding to approximately 131 hours, annually. In 2021, all six observed yellow dust events occurred in spring (March to May). PM10, PM2.5, and PM1.0 concentrations increased from January to March, peaked in March, decreased until September, and rose again. The coarse fraction ratio increased stepwise from February to May, likely due to yellow dust and episodes of high PM concentration in the spring. The PM1.0 concentration was higher in summer and fall compared with that in spring and winter. The PM1.0/PM2.5 ratio was highest in summer and fall even though the annual PM1.0concentration was lowest, suggesting a higher secondary formation rate of fine particles during these periods. This underscores the need for further scientific investigation on PM1.0. The study provides insights into the simultaneous observation and distribution characteristics of PM10, PM2.5, and PM1.0, highlighting the mass concentration, distribution, and ratio of PM1.0. These findings are crucial for understanding PM distribution in Ansan, an industrial complex, and can serve as essential data for chemical composition comparisons, data validation, public health strategies, and cost-benefit analyses for regional PM improvement.
Analysis of the Governance Maturity of Intangible Assets and Processes as a Tool for Implementing Knowledge Management in a Pharmaceutical Industry
Authors: Magalhães Jorge , De Souza Antunes Adelaide Maria , Santos Sandro
Published: September 2024

Information and Knowledge Management is used to improve the performance of companies' innovative activities. Before implementing a management process, organizations must analyze its aspects related to the dynamics of internal knowledge, whether tacit or explicit. Thus, information management for maturity monitoring constitutes a tool capable of enabling and implementing initiatives in a systematic and structured way. They allow us to continually improve the governance of innovation and projects. In this way, this article contributes to improving information management through a maturity level model and with proposals for improvement for acting and sustainability of the strategic governance of its intellectual assets. Interviews conducted based on the model proposed by Batista (2012) but applied in a pharmaceutical company. After identifying the scenario, the relationship between the critical success factors of managing its processes and knowledge innovation was evaluated. With the degree of maturity obtained, it was compared against the “ideal” degrees and a management plan for projects and processes proposed.
Educação Continuada sobre Terminologias Clínicas no Contexto da Saúde Digital
Authors: Galvão Maria Cristiane Barbosa , Santos Silvana de Lima Vieira dos , Braga Renata Dutra , Ricarte Ivan Luiz Marques , Oliveira Thais Lucena de
Published: September 2024

The workforce of a health system is multidisciplinary, requiring interprofessional training and specific knowledge to work in the context of digital health, such as those about health terminologies. Thus, the study aimed to present the creation, implementation and evaluation process of a course on health terminologies focused on professionals working in the Brazilian Health System. For that, documentary research was developed associated with data obtained from an opinion poll. The health terminology course included the development of an e-book, video lessons and other teaching materials, being implemented via Moodle. Its first offer was held in 2022 and had the participation of 136 health professionals who, as a whole, stated that the course contributed to expanding their knowledge of health terminologies. Overall satisfaction with the course and with the didactic material was higher among participants over 31 years old. It is recommended that distance learning initiatives on the topic of health terminologies be developed, as well as a longitudinal follow-up of graduates to better understand the impact of the knowledge acquired in the daily lives of these professionals.
Hermenêutica e Organização e Representação da Informação
Authors: Oliveira Walter Clayton de , Augusto Chaves Guimarães José
Published: September 2024

This article addresses the intersection between Hermeneutics and Information Organization and Representation, emphasizing the importance of transversality and verticality in the context of Information Science. Hermeneutics, as an interpretative approach, is essential to comprehend the complexity of information, considering cultural, historical, and social contexts. Simultaneously, Information Organization and Representation aim to structure and give meaning to data, facilitating access and understanding. Transversality refers to the integration of these elements horizontally, while verticality involves depth in the analysis and interpretation of information. The combination of these approaches enriches research in Information Science, providing a more comprehensive and contextualized understanding of the crucial role of information in contemporary society.
25 anos do PPGCI Unesp
Authors: Santos Plácida Leopoldina Ventura Amorim da Costa
Published: September 2024

Desde a sua instalação há 25 anos, o Programa de Pós-Graduação em Ciência da Informação (PPGCI), da Unesp, tem sido uma referência na formação de profissionais altamente qualificados e na produção de pesquisas de relevância científica e, ao longo dessas duas décadas e meia, a equipe de pesquisadores acadêmicos e o PPGCI enfrentaram diversos desafios, superaram obstáculos e celebraram conquistas notáveis.
Ao procurar reconstruir a trajetória percorrida pelo PPGCI evidencia-se a importância de descrever a capacidade de regência dos fatores de precedência, no momento de construção de uma proposta para a criação de um Programa Acadêmico de Pós-Graduação.
AVALIAÇÃO DA ATIVIDADE CITOTÓXICA E ANTITUMORAL IN VITRO E IN VIVO DE EXTRATOS DA Urtica dioica L.:
Authors: Lopes Yoná Christina de Andrade , Sousa Francisca Jennifer Carvalho de
Published: September 2024

Introdução: A Urtica dioica é uma planta perene comestível muito utilizada desde a antiguidade na medicina tradicional para o tratamento de diversas doenças, tais como diabetes, reumatismo, coadjuvante no tratamento de hiperplasia prostática, na prevenção de doenças do sistema cardiovascular, como antimicrobiano, dentre outros. Objetivo: realizar uma revisão com as informações disponíveis na literatura científica dos extratos obtidos de partes vegetais de U. dioica com atividade anticâncer e citotóxica, bem como elucidar a ação antioxidante dos extratos sobre as células tumorais tanto em modelos animais quanto in vitro.  Metodologia: A busca de dados foi realizada por meio das bases de dados Web of Science, LILACS e MEDLINE via PubMed, para a coleta de estudos publicados anteriormente à agosto de 2024. Para a pesquisa foi utilizado os termos e palavras-chave, como: “Cytotoxicity”, “Cancer”, “Medicinal plants”, “Urtica dioica” e “Phytotherapy”, utilizando a estratégia de busca com a combinação de operadores booleanos “AND”. Após a análise dos critérios, foram selecionados 10 artigos para constituir a discussão dos resultados. Resultados: As informações disponíveis na literatura científica acerca de compostos bioativos com atividade citotóxica e antitumoral, observando os resultados de tratamentos com extrato de U. dioica a nível celular e molecular em várias linhagens de células cancerosas em modelos experimentais in vitro e in vivo. Considerações: Os extratos estudados da U. dioica podem agir como anticancerígeno em vários mecanismos através da ação do metabolismo, na inibição do crescimento celular, na indução das expressões de genes pró-apoptóticos, antiapoptóticos e nas proteínas envolvidas na via apoptótica em diferentes linhagens de células cancerosas in vitro e de modelos animais de câncer, devido a suas propriedades citotóxicas e antitumoral. No entanto, observou-se a escassez de estudos que tenham foco na atividade antioxidante, desse modo, mais investigações são necessárias para identificar o(s) composto(s) ativo(s) nos extratos da U. dioica.
Artrite Reumatoide: Patogênese, Diagnóstico e Abordagens Terapêuticas
Authors: Claudia Mascari Anna , Zanin Caldas Julia , Ferreira Rocha de Aguiar Alberto , Suhre Cadore Leonardo , Henrique de Oliveira Aurich João , Carvalho Couto Eduardo , Claudia Nogueira Saraiva Maria , Auceliano Coelho Pinheiro Lucas , Soares França Costa e Silva Paola , Andrade Afonso Luana , Marinho Porto Lima Davi , PAZA FERREIRA GUILHERME
Published: September 2024

Introdução: A artrite reumatoide (AR) é uma doença inflamatória autoimune que afeta principalmente articulações, causando dor e perda funcional. Com prevalência entre 0,5% e 1%, é mais comum em mulheres, com pico de incidência entre 40 e 60 anos. O diagnóstico precoce e tratamentos modernos, como DMARDs e inibidores de JAK, são essenciais para melhorar a qualidade de vida. Metodologia: O estudo sobre "Artrite Reumatoide: Patogênese, Diagnóstico e Abordagens Terapêuticas" realizou buscas em bases científicas de 2014 a 2024, utilizando critérios específicos. Foram priorizados artigos sobre patogênese, diagnóstico e tratamento multidisciplinar. A análise crítica dos dados avaliou a qualidade dos estudos, identificando práticas clínicas eficazes e colaborativas para melhorar o manejo da doença. Resultados e discussões: A artrite reumatoide afeta articulações e tecidos sistêmicos. Fatores genéticos, como o HLA-DRB1, combinados com influências ambientais, promovem a produção de autoanticorpos, inflamação crônica e destruição articular. O diagnóstico precoce e tratamentos inovadores, como DMARDs e inibidores de JAK, melhoram o prognóstico. Abordagens personalizadas e intervenções de estilo de vida, como dietas anti-inflamatórias, complementam a terapia, oferecendo um manejo mais eficaz e holístico. Considerações finais: Avanços na compreensão dos mecanismos moleculares e no uso de biomarcadores, como ACPA e fator reumatoide, têm permitido diagnóstico precoce e tratamentos mais eficazes na artrite reumatoide. Terapias biológicas e inibidores de JAK revolucionaram o manejo, enquanto abordagens personalizadas e holísticas contribuem para melhor qualidade de vida. Desafios persistem na busca por novos biomarcadores e terapias inovadoras.
Improving the Efficiency of Applying Thermal Energy into the Formed Protective Coatings Based on Rubber Mastic
Authors: Сапелкин Р.И. , Матренинский С.И. , Мищенко В.Я. , Бредихина Н.В.
Published: September 2024

Постановка задачи. Для устройства защитного покрытия трубного металла из низкомолекулярного олигодиена (каучуковой мастики) необходимо обеспечить внесение в материал покрытия требуемого количества тепловой энергии, что посредством вулканизации каучуковой мастики формирует высокие физико-механические и эксплуатационные характеристики защитного слоя. Данный результат может быть достигнут путем разработки и применения высокоэффективных теплогенерирующих устройств. Результаты. Предложен способ эффективного внесения тепловой энергии в каучуковую мастику методом индукционного нагрева трубного металла, а также разработано и сконструировано опытное теплогенерирующее устройство, реализующее данный способ и обеспечивающее необходимые режимы термообработки композиционного материала покрытия. Выводы. Сконструированное теплогенерирующее устройство, реализующее эффективный способ внесения тепловой энергии в каучуковую мастику, позволяет обеспечить необходимый температурный режим в целях формирования защитного покрытия с необходимым набором физико-механических и эксплуатационных характеристик.

Statement of the problem. For the device of a protective coating of tubular metal made of low molecular weight oligodiene (rubber mastic), it is necessary to ensure that the required amount of thermal energy is introduced into the coating material, which, through vulcanization of rubber mastic, forms high physical, mechanical and operational characteristics of the protective layer. This result can be achieved through the development and application of highly efficient heat generating devices. Results. A method for the effective introduction of thermal energy into rubber mastic by induction heating of tubular metal is proposed, and an experimental heat generating device has been developed and constructed that implements this method and provides the necessary heat treatment modes for the composite coating material. Conclusions. The designed heat generating device, which implements an effective method of introducing thermal energy into rubber mastic, allows to ensure the necessary temperature regime in order to form a protective coating with the necessary set of physical, mechanical and operational characteristics.
Prefab: New Technologies and Prospects of the Construction Industry
Authors: Евсевнина Е.Д. , Воробьев В.С.
Published: September 2024

Состояние проблемы. Основными факторами в строительной отрасли являются: стоимость реализации проекта, его продолжительность и уникальность. Их достижению способствует развиваемая в настоящее время префабрикация, суть которой сводится к фабричному или заводскому изготовлению деталей с последующей их сборкой в конструктивные элементы, модули и в целом объекты. Вместе с тем до настоящего времени не отработаны технологии, организация строительства и управление префаб-процессами. Результаты. Предложен системный обзор реализации зданий по префаб-технологии с высокой фабричной готовностью. Приведен обзор модулей, которые могут быть интегрированы в проекты, построенные на месте, с меньшим количеством отходов и более высоким контролем качества по сравнению с проектами, в которых используется традиционный тип строительства. Подчеркнуто отличие метода префабрикации от модульной сборки строительного объекта. Дан обзор префаб-продуктов, представленных на рынке в настоящее время. Выводы. Обоснованы направления повышения качества производимых зданий, присущих префаб-технологиям, а также экологичность и энергоэффективность данной технологии. Приведен фрагмент BIM-модели с календарно-строительным графиком строительства префаб-дома, префаб-технологии, применяемых в России и, в частности, в г. Новосибирске.

Statement of the problem. The main factors in the construction industry are: the cost of the project, its duration and uniqueness. Their achievement is facilitated by the currently developing pre-fabrication, the essence of which is reduced to the factory or factory manufacture of parts with their subsequent assembly into structural elements, modules and objects in general. At the same time, technologies, organization of construction and management of prefab processes have not been worked out to date. Results. A systematic review of the implementation of buildings using prefab technology with high factory readiness is proposed. An overview of modules that can be integrated into on-site projects with less waste and higher quality control compared to projects that use a traditional type of construction is provided. The difference between the prefab method and the modular assembly of a construction object is emphasized. An overview of the prefab products currently on the market is given. Conclusions. The article substantiates the directions of improving the quality of manufactured buildings inherent in prefab technologies, as well as the environmental friendliness and energy efficiency of this technology. A fragment of a BIM model with a calendar and construction schedule for the construction of a prefab house, prefab technologies used in Russia and in particular in Novosibirsk, is presented.
Analysis of a Design Solution for the Bearing Structure of an Industrial Building Using the LIRA-SAPR Software Complex
Authors: Пушкарев И.А. , Рычина С.А.
Published: September 2024

Постановка задачи. Проведен анализ конструктивного решения несущей конструкции производственного здания по двум вариантам расчетных схем при использовании программного комплекса «ЛИРА-САПР». Результаты. С помощью программного комплекса «ЛИРА-САПР» были рассмотрены два варианта конструирования, что создало полное представление о работе профиля и подтвердило необходимость проверки элементов фермы с учетом возникновения изгибающего момента в случае жесткого сопряжения стержней. Стремительное развитие программных комплексов дает возможность рассчитать различные варианты схем конструкций и сократить время данной операции. Принимая в расчетных моделях различные типы соединения, пользователь может наглядно увидеть наиболее выгодное напряженно-деформированное состояние стержней ферм, что, в свою очередь, позволит избежать негативных последствий при эксплуатации производственного здания. Выводы. Построены мозаики усилий с жестким и шарнирным сопряжением стержней в узлах фермы, которые показали, что в элементах верхнего пояса и восходящих раскосах наибольший процент использования сечений соответствует проверке на устойчивость, а в элементах нижнего пояса и нисходящих раскосах наибольший процент использования сечений приходится на проверку по нормальным напряжениям. В ферме с жестким сопряжением стержней в узле процент использования сечения выше, чем при шарнирном соединении, как при проверке по нормальным напряжениям, так и по устойчивости.

Statement of the problem. An analysis of the design solution of the load-bearing structure of an industrial building was carried out using two variants of design schemes, using the LIRA-SAPR software package. Results. Using the Lyra-SAPR software package, two design options were considered, which created a complete picture of the operation of the profile and confirmed the need to check the truss elements taking into account the occurrence of a bending moment in the case of a rigid coupling of the rods. The rapid development of software systems makes it possible to calculate various options for structural schemes and reduce the time of this operation. By accepting various types of connections in the calculation models, the user can clearly see the most favorable stress-strain state of the truss rods, which in turn will help avoid negative consequences during the operation of the industrial building. Conclusions. Mosaics of forces with rigid and hinged coupling of rods in the truss nodes were constructed, which showed that in the elements of the upper chord and ascending braces the largest percentage of the use of sections corresponds to the stability test, and in the elements of the lower chord and descending braces the largest percentage of the use of sections falls on the normal test stress. In a truss with a rigid coupling of bars in a node, the percentage of section utilization is higher than with a hinged connection, both when tested by normal stresses and by stability.