bluuebunny/crossref_metadata_2025 huggingface dataset:
New Strategies for the Delivery of Some Natural Anti-oxidants with Therapeutic Properties
Authors: Esposito Elisabetta , Drechsler Markus , Puglia Carmelo , Cortesi Rita
Published: March 2019

Nature offers tremendous potential in the medicine field. Natural antioxidant molecules inhibit or quench free radical reactions and delay or inhibit cellular damage. In the last few years, researchers have been focusing on the health benefits of natural products. Particularly some dietary nutrients, such as curcumin, crocin, resveratrol, quercetin, coenzyme Q10, vitamin C, as well as some polysaccharides have been evaluated for their numerous and unique therapeutic properties. This review focuses on examples of pharmaceutical applications of natural anti-oxidants, with special regards to their encapsulation in micro- and nano- delivery systems. In vitro and in vivo studies have been conducted to investigate the physicochemical and pharmacological properties of different delivery systems containing antioxidant molecules. For instance, ethosomes, organogels, monoolein aqueous dispersions and solid lipid nanoparticle have been considered. It was found that micro and nanoencapsulation strategy can improve the solubility of lipophilic molecules and the chemical stability of labile antioxidants, thus prolonging their efficacy. In vitro and in vivo studies have highlighted that antioxidant encapsulation prolongs release kinetics, bioavailability and antioxidant effects. Noticeably, some encapsulated antioxidants effectively inhibit cancer cell proliferation, cell migration and colony formation, thus suppressing cancer progression.
Screening of Anti-mycobacterial Phytochemical Compounds for Potential Inhibitors against Mycobacterium Tuberculosis Isocitrate Lyase
Authors: Tiwari Ashish , Kumar Akhil , Srivastava Gaurava , Sharma Ashok
Published: March 2019

Conclusion:

Phytochemical based anti-mycobacterial compound can further developed into effective drugs against persistence tuberculosis with lesser toxicity and side effects.

Results:

Docking and MD simulation studies of top hit compounds have identified shinjudilactone (quassinoid), lecheronol A (pimarane) and caniojane (diterpene) as potential MtbICL inhibitors.

Methods:

Virtual screening, molecular docking and MD simulation study has been integrated for screening of phytochemical based anti-mycobacterial compounds. Docking study of reported MtbICL inhibitors has shown an average binding affinity score -7.30 Kcal/mol. In virtual screening, compounds exhibiting lower binding energy than calculated average binding energy were selected as top hit compounds followed by calculation of drug likeness property. Relationship between experimental IC50 value and calculated binding gibbs free energy of reported inhibitors was also calculated through regression analysis to predict IC50 value of potential inhibitors.

Background and Introduction:

Tuberculosis (TB) is a leading infectious disease caused by Mycobacterium tuberculosiswith high morbidity and mortality. Isocitrate lyase (MtbICL), a key enzyme of glyoxylate pathway has been shown to be involved in mycobacterial persistence, is attractive drug target against persistent tuberculosis.
Psychosocial Risk Factors and Ischemic Heart Disease: A New Perspective
Authors: Roncella Adriana
Published: March 2019

Background:

Cardiovascular disease is the most common cause of morbidity and mortality
worldwide, with ischemic heart disease (IHD) accounting for roughly 50% of these events in industrialized
nations.

:

In recent years, the relative importance of IHD in less industrialized countries is also rising at an
alarming and steadily-increasing rate.

Objective:

Many experimental, observational and epidemiological studies have demonstrated the
importance of psychosocial risk factors in the development and clinical manifestations of IHD. They
act both indirectly, associated with an unhealthy lifestyle; and directly, through the activation of inflammatory
cascades and the sympathetic nervous system. They also cluster with biological risk factors
to increase the incidence and clinical manifestations of IHD. From these assumptions, there
emerges the potential that an integrated approach that incorporates psychological therapy in various
forms might reduce IHD patients’ symptoms and maladaptive behaviors, and thereby enhance their
prognosis.

Methods:

To date, three psychotherapeutic approaches have been utilized within cardiac psychology
practice: (1) cognitive-behavioral psychotherapy; (2) psychodynamic psychotherapy; and (3) ontopsychological
psychotherapy. The current article briefly describes these three approaches and how
their use might enhance the care of IHD patients.

Results:

A range of psychological characteristics influence the development, course and management
of cardiac patients’ IHD. Among others, these include patients’ emotions, attitudes, behaviors, relationships,
and stressors. State-of- the-art literature suggests that psychological interventions should
be considered in much the same way as medical interventions, in terms of their relevance to both patient
management and outcomes.

Conclusion:

For this reason, it is essential that professional psychological and psychotherapeutic
support be rendered available to cardiology patients, as a means to enhance both the effectiveness
and efficiency of care.
Psychotropic Medication of Acute Episodes of Mood Disorders: Current Prescription Attitude in Two Psychiatric Wards in Cagliari, Italy
Authors: Baggiani Gioia , Ambrosiani Luca , Trincas Pierfranco , Burrai Caterina , Bocchetta Alberto
Published: March 2019

Background:

Medication of acute episodes of mood disorders has changed over the last decades following the results of randomized clinical trials.

Objective:

The aim of this study was to analyze medication prescribed at discharge from two psychiatric wards. We focused on hospitalization as one of the best opportunities to start prophylaxis.

Methods:

We examined retrospectively the clinical records of 357 patients hospitalized for mood episodes in two psychiatric wards in the Cagliari area (SPDC-1 and SPDC-2) between 1 January and 31 December 2016. We focused on the psychotropic medication prescribed at discharge from the hospital.

Results:

Most patients were discharged with antipsychotics (86%) and/or benzodiazepines (89%). Combined medication was frequent, including various co-administration of first-generation and/or second-generation antipsychotics (26% of patients), or antipsychotics combined with mood-stabilizers (51% of patients). There was a preferential prescription of first-generation antipsychotics in SPDC-1, and of second-generation antipsychotics in SPDC-2. Prescription of lithium was significantly more frequent in SPDC-1.

Conclusion:

Although the treatment was in line with randomized clinical trials, the choice of individual psychotropic agents differed significantly between the two wards. Different prescription attitudes can have consequences on the long-term outcome of patients discharged from the hospital after an acute mood episode.
Synthesis and Characterization of Valacyclovir HCl Hybrid Solid Lipid Nanoparticles by Using Natural Oils
Authors: Chacko Archana , Newton Amaldoss M.J.
Published: March 2019

Background:

The Jojoba Simmondsia Chinensis oil is used as one of the main ingredients
which has an antioxidant, moisturizing and stabilizing activity. Likewise, grape seed (Vitis vinifera) oil
is also used in this preparation which also has some remarkable medicinal properties such as antioxidant,
astringent and is also used as a moisturizer. The Valacyclovir Solid Lipid Nanoparticles (SLN)
are prepared in combination.

Objective:

The prime objective of the study was to prepare a nanodispersion with good stability indicating
zeta potential. The formulations were prepared by varying concentrations of jojoba oil and grape
seed oil which form the hybrid nanoparticles with the drug.

Methods:

The high-pressure hot-homogenization technique was used to prepare the nanoparticles. The
prepared nanoparticles were subjected to characterization analysis such as Mean particle size, Zaverage,
and Zeta potential by using Dynamic Light Scattering (DLS) and Photon Correlation Spectroscopy
(PCS). The best formulation was subjected to Transmission Electron Microscopy (TEM)
technique for surface morphology and other characterizations. The crystalline pattern of the drug alone,
drug-loaded nanoparticles and nanoparticles without the drug was studied by XRD. The drug excipients
compatibility studies were performed by using Fourier-Transform Infrared Spectroscopy (FTIR)
Differential Scanning Calorimetry and (DSC). The other factors such as in vitro drug release, and %
drug entrapment efficiency were studied by using suitable methods.

Results:

The results demonstrated that the particles are in nano range with good stability with appreciable
Zeta potential (-48.2±mV). The selected formulations were analyzed for MPS which demonstrated
the value of 306.7±183.4 and 416.5±289.3. The best formulation VNP5 demonstrated the Bellshaped
curve and confirmed the uniform distribution.

Conclusion:

Based on the patents, it was demonstrated that valacyclovir is widely used in the treatment
and prophylaxis of viral infections in human, particularly infections caused by the herpes group
of viruses. Valacyclovir is an effective drug for the treatment of cold sores.
How New Technologies Can Improve Prediction, Assessment, and Intervention in Obsessive-Compulsive Disorder (e-OCD): Review
Authors: Ferreri Florian , Bourla Alexis , Peretti Charles-Siegfried , Segawa Tomoyuki , Jaafari Nemat , Mouchabac Stéphane
Published: March 2019

Background

New technologies are set to profoundly change the way we understand and manage psychiatric disorders, including obsessive-compulsive disorder (OCD). Developments in imaging and biomarkers, along with medical informatics, may well allow for better assessments and interventions in the future. Recent advances in the concept of digital phenotype, which involves using computerized measurement tools to capture the characteristics of a given psychiatric disorder, is one paradigmatic example.

Objective

The impact of new technologies on health professionals’ practice in OCD care remains to be determined. Recent developments could disrupt not just their clinical practices, but also their beliefs, ethics, and representations, even going so far as to question their professional culture. This study aimed to conduct an extensive review of new technologies in OCD.

Methods

We conducted the review by looking for titles in the PubMed database up to December 2017 that contained the following terms: [Obsessive] AND [Smartphone] OR [phone] OR [Internet] OR [Device] OR [Wearable] OR [Mobile] OR [Machine learning] OR [Artificial] OR [Biofeedback] OR [Neurofeedback] OR [Momentary] OR [Computerized] OR [Heart rate variability] OR [actigraphy] OR [actimetry] OR [digital] OR [virtual reality] OR [Tele] OR [video].

Results

We analyzed 364 articles, of which 62 were included. Our review was divided into 3 parts: prediction, assessment (including diagnosis, screening, and monitoring), and intervention.

Conclusions

The review showed that the place of connected objects, machine learning, and remote monitoring has yet to be defined in OCD. Smartphone assessment apps and the Web Screening Questionnaire demonstrated good sensitivity and adequate specificity for detecting OCD symptoms when compared with a full-length structured clinical interview. The ecological momentary assessment procedure may also represent a worthy addition to the current suite of assessment tools. In the field of intervention, CBT supported by smartphone, internet, or computer may not be more effective than that delivered by a qualified practitioner, but it is easy to use, well accepted by patients, reproducible, and cost-effective. Finally, new technologies are enabling the development of new therapies, including biofeedback and virtual reality, which focus on the learning of coping skills. For them to be used, these tools must be properly explained and tailored to individual physician and patient profiles.
The Impact of an Electronic Patient Bedside Observation and Handover System on Clinical Practice: Mixed-Methods Evaluation (Preprint)
Authors: Lang Alexandra , Simmonds Mark , Pinchin James , Sharples Sarah , Dunn Lorrayne , Clarke Susan , Bennett Owen , Wood Sally , Swinscoe Caron
Published: March 2019

BACKGROUND

Patient safety literature has long reported the need for early recognition of deteriorating patients. Early warning scores (EWSs) are commonly implemented as “track and trigger,” or rapid
response systems for monitoring and early recognition of acute patient deterioration. This study presents a human factors evaluation of a hospital-wide transformation in practice, engendered by the deployment of an innovative electronic observations (eObs) and handover system. This technology enables real-time information processing at the patient’s bedside, improves visibility of patient data, and streamlines communication within clinical teams.

OBJECTIVE

The aim of this study was to identify improvement and deterioration in workplace efficiency and quality of care resulting from the large-scale imposition of new technology.

METHODS

A total of 85 hours of direct structured observations of clinical staff were carried out before and after deployment. We conducted 40 interviews with a range of clinicians. A longitudinal analysis of critical care audit and electronically recorded patient safety incident reports was conducted. The study was undertaken in a large secondary-care facility in the United Kingdom.

RESULTS

Roll-out of eObs was associated with approximately 10% reduction in total unplanned admissions to critical care units from eObs-equipped wards. Over time, staff appropriated the technology as a tool for communication, workload management, and improving awareness of team capacity. A negative factor was perceived as lack of engagement with the system by senior clinicians. Doctors spent less time in the office (68.7% to 25.6%). More time was spent at the nurses’ station (6.6% to 41.7%). Patient contact time was more than doubled (2.9% to 7.3%).

CONCLUSIONS

Since deployment, clinicians have more time for patient care because of reduced time spent inputting and accessing data. The formation of a specialist clinical team to lead the roll-out was universally lauded as the reason for success. Staff valued the technology as a tool for managing workload and identified improved situational awareness as a key benefit. For future technology deployments, the staff requested more training preroll-out, in addition to engagement and support from senior clinicians.
Методы анализа редких и благородных металлов – пути развития
Authors: Родинков О.В. , Журавлева Г.А.
Published: March 2019

В обзорной статье по материалам доклада на 76-х Курнаковских чтениях (декабрь 2018 года) описаны этапы развития методов аналитической химии редких и благородных металлов, начиная с середины 19 века. Показана эволюция физических методов анализа, в основе которых лежит теория измерения аналитического сигнала, строго специфичного для каждого химического элемента. За прошедшее столетие сформировались инструментальные методы неорганического анализа – атомно-спектральные, рентгеновские, масс-спектральные и радиоаналитические, которые в принципе пригодны для решения задач по анализу редких, редкоземельных, благородных металлов и материалов на их основе. Обсуждаются проблемы, значение и масштабы использования редких элементов и благородных металлов в науке и производстве. Отмечен вклад выдающихся ученых 20 века – академиков Н. П. Сажина, Н. С. Курнакова, И. П. Алимарина и др. в теорию химического анализа и изучения состава, строения и свойств редких элементов и благородных металлов. Затронут вопрос становления новых методов аналитической нанодиагностики. Намечены пути и перспективы развития этого направления аналитической химии.
Особенности концентрирования полярных биологически активных соединений на сверхсшитом полистироле
Authors: Дмитриенко С.Г. , Апяри В.В. , Толмачева В.В.
Published: March 2019

Систематизированы сведения об особенностях концентрирования полярных биологически активных соединений на сверхсшитом полистироле (ССПС) – коммерчески доступном микропористом полимерном сорбенте – в целях химического анализа. Даны общие характеристики сверхсшитых полистиролов. Приведены примеры сорбции на сорбентах этого типа соединений разных классов – метилксантинов, сульфаниламидов, тетрациклинов, флавоноидов и др. Обсуждены различные приемы аналитического концентрирования с применением ССПС и сочетания концентрирования с методами последующего определения. Показаны возможности группового концентрирования органических соединений на ССПС, а также прямого (без пробоподготовки) извлечения целевых аналитов из анализируемых объектов.
Uso de las ciencias ómicas para el mejoramiento genético de cultivos
Authors: Botero O. Kelly , Arias Tatiana
Published: March 2019

El crecimiento de la población, el cambio climático y la pérdida de los servicios ecosistémicos, son algunos de los desafíos que enfrenta el sector agrícola en las últimas décadas para garantizar la seguridad alimentaria a largo plazo. Los programas de mejoramiento genético son un frente de acción que puede contribuir al desarrollo de materiales genéticos adaptados a nuevas condiciones ambientales. El desarrollo y la implementación de tecnologías de secuenciación de alto rendimiento han permitido acelerar dichos programas en cultivos que alimentan a la mayoría de la población mundial. El propósito de este artículo es revisar algunos de los desarrollos tecnológicos de las ciencias ómicas para el estudio de mejoramiento genético de cultivos. En este trabajo se discuten cuatro enfoques de las ciencias ómicas y sus aplicaciones en la agricultura: la filogenómica, la genómica comparativa, la transcriptómica comparativa y la selección asistida por marcadores moleculares. Estos enfoques permiten comprender la historia evolutiva de cultivos y sus parientes silvestres, identificar la estructura y función de los genes de interés en la agricultura, revelar la expresión de los genes importantes en el proceso de domesticación y caracterizar molecularmente individuos de especies agrícolas, con el fin de evidenciar variaciones genéticas que permitan agilizar procesos de selección. Es necesario implementar programas de mejoramiento genético que incluya el uso de algunas, o todas estas tecnologías con el propósito de acelerar los resultados de dichos procesos y contribuir a los desafíos del sector agrícola.
Accounting values and metrics for the sustainable exploitation of intangible heritage assets related to food and agriculture
Authors: Pavone Pietro
Published: March 2019

This research paper is focused on corporate groups, one of the most widespread corporate organisational solutions in managing global business deals. We analyse the changes in the organisation of companies that have completed their internationalisation process or that are about to do so. We focus on how the tasks and responsibilities of the main internal control staff have changed and the relationship with the various management bodies. In particular, we will try to discover how corporate groups with an international vocation reconcile the need to manage tax variables with the need to ensure that the group’s central management team does not merely pursue interests that are common to all the group’s subsidiaries but, rather, manages a real enterprise comprising various legal entities. The paper culminates by proposing certain operational tools designed on the logic of enterprise risk management that can guarantee advanced and strategic management of the tax risks associated with international business.
The effects of crypto-currencies on financial market and monetary policy
Authors: Chun Se-Hak
Published: March 2019

The emergence of crypto-currency breaks the concept of existing currency. Against this backdrop, there is a move to issue Central Bank Digital Currency. In addition to the regulation on crypto-currency, it is to distribute the crypto-currency example directly so as not to confuse the financial policy with private crypto-currency. This study examines the effects of crypto-currency on financial markets, especially its effects on monetary policy, and discusses implications for central bank’s issuing digital currency
The relationship between innovation and the financial structure with consideration of the moderating role of the generational stage of family businesses
Authors: Chibani Faten , Henchiri Jamel Eddine , Kefi Mohamed Karim
Published: March 2019

This research aims to empirically test the relationship between the financial structure and innovation in family businesses. The notion of innovation is, indeed, a sustainability factor for family businesses which favors the conceptual incorporation into the capital structure of family businesses. This paves us the way to analyze the relationship by mobilizing the theory of resources. This research also enables us to verify the moderating role of the generational stage in this relationship. The model estimates are based on a sample of panel data collected over the period 2003-2012 for 100 unlisted French Family firms. The main results indicate that all the traditional determinants of the financial structure, except ROA, play an important role in the financing policy of these firms. We can perceive that innovation can affect the choice of financing and can, also, play a significant role in the choice of debt maturity. Moreover, the financial structure of these family businesses slowly but surely converges towards its target level
35 years of literature on corporate governance in banks: Risk management, ownership and compensation
Authors: Lagasio Valentina
Published: March 2019

This paper provides a systematic literature review on the literature on corporate governance in banks. The review is conducted over academic papers published in the period 1980-2015, identifying 35 years of evolution in the core aspects of banking corporate governance: risk management, ownership structure and executive compensation of banks. Best practices for increasing performance and reducing risk in banks are commented, when identified. Gaps in the literature and lack of univocal consensus on the different implementation of corporate governance in the selected topic are also identified
Corporate governance of banks, performance, market and capital structure
Authors: Lazarides Themistokles
Published: March 2019

Many scholars have linked Corporate Governance (CG) and performance or CG, capital structure of banks or market structure. The decision to use the capital market or debt in order to obtain the necessary capital to finance firms’ operations is a critical factor for the formulation of corporate environment, because it contributes to the ownership concentration or diffusion and to corporate risk exposure level. The paper’s goal is to link all these three dimensions and to address the issue of whether performance and capital structure are the decisive factors of good corporate governance or vice versa and whether these dimensions are the drivers of banks’ financial health, strategic robustness and survival effectiveness. Furthermore, the paper is seeking to detect the differences (if any) among banking systems across Europe. To do that a double sample is selected (covering the period from 2004 to 2013). The first sample is comprised by European banks that merged. The second sample is comprised by European banks that survived the last merger & acquisition wave and the systemic shock of the double crises of 2002 and 2008. A combined ratio of performance (ROAA or ROEA) and debt to equity (DE or debt aggravation) is used to determine if there is a connection between capital structure and CG quality of banks. Panel data methodology is used. The econometric results show that there are no significant differences between the strata that are used for this research. There is no common factor or driver between the banking systems of Europe. This is an indication that the convergence theory of corporate governance systems is yet confirmed
Role of taste perception in white spot lesion formation during orthodontic treatment
Authors: Alanzi Abrar , Velissariou Marianna , Al-Melh Manal Abu , Ferguson Donald , Kavvadia Katerina
Published: March 2019

Objectives:

To investigate the role of individual's taste sensitivity using 6-n-propylthiouracil (PROP) in the development of white spot lesions (WSLs) in adolescent orthodontic patients.

Materials and Methods:

44 healthy adolescents, aged 12 to 16 years old, who were in fixed-appliance orthodontic treatment for at least 6 months, consented to participate in this cross-sectional study. Data regarding participants' demographic information, oral hygiene practices, and dietary habits were obtained by a questionnaire. An oral clinical examination was performed to determine the oral hygiene status, the presence of WSLs and dental caries experience. The taste phenotype of the participants was evaluated through PROP test and they were accordingly divided into PROP nontasters and PROP tasters.

Results:

The sample consisted of 24 subjects in the WSL group and 20 subjects in the WSL-free group. The WSL group demonstrated higher mean plaque score (48.2), mean decayed, missing, and filled surfaces (2.38), and mean decayed, missing, and filled teeth (1.96) scores compared to the WSL-free group (38.7, 0.85, and 0.55, respectively), but no significant differences were found. Most subjects in the WSL group were PROP nontasters (66.6%) whereas most subjects in the WSL-free group were PROP tasters (75%); a significant difference was observed between the groups (P = .006).

Conclusions:

The prevalence of white spot lesions was significantly higher in adolescent orthodontic patients who were PROP nontasters compared to PROP tasters. A PROP taste perception could be a potential risk factor for the formation of WSLs during fixed orthodontic treatment that warrants further attention.
PENATAAN RUANG HALTE TRANS JOGJA DI BANDARA ADISUCIPTO YANG BERBASIS ERGONOMI DENGAN PROGRAM THE SIMS 3
Authors: Anggraeni Dhita Wahyu
Published: March 2019

Trans Jogja Shelter in Yogyakarta Adisucipto airport is one of the shelters, which is in great public demand, because it integrates with other transport modes. The airport bus shelter is full of passengers with different human dimensions and their luggage. Based on initial observations about movement circulation during rush hour, it was found such difficulties in movement system and led to insecurity for the passengers. The purpose of this study is to analyze the circulation layout based on ergonomic needs at the Trans Jogja shelter in Adisucipto Airport area, which may contributes to the circulation moving system. Criteria of the study are four aspects, i.e the anthropometric, kinetic, physiology, and psychology. This study used behavioral mapping and simulation methods. The Sims 3 program is used for the simulation of human movement in the shelter. The analysis found that the shelter does not meet the need of standard dimensional human motion. In order to improve the quality of a better layout of the shelters, the ergonomic movement system is indispensable to be taken into consideration.Keywords: circulation space, ergonomics, The Sims 3 programAbstrak: Halte Trans Jogja di Bandara Adisucipto Yogyakarta adalah salah satu halte yang banyak dibutuhkan oleh masyarakat karena terintegrasinya berbagai jalur tranportasi yang memberi kemudahan bagi masyarakat dalam memilih tujuan perjalanan. Halte bandara dipenuhi oleh calon penumpang bus dengan bermacam dimensi ukuran tubuh dan barang bawaan. Berdasarkan pengamatan awal ditemukan permasalahan sirkulasi dan gerak terutama pada saat kondisi jam sibuk, banyaknya pengguna halte menyebabkan kesulitan bergerak dan mengakibatkan rasa tidak aman bagi calon penumpang bus. Tujuan penelitian ini adalah mengkaji permasalahan ergonomi pada tata ruang sirkulasi Halte Trans Jogja di Bandara Adisucipto melalui studi gerak sesuai ergonomi. Hasil kajian memberi konstribusi terhadap kenyamanan gerak bagi pengguna halte khususnya masyarakat Yogyakarta. Tolok ukur dalam penelitian ada empat aspek yaitu anthropometri, kinetik, fisiologi dan psikologi. Metode yang digunakan dalam penelitian ini adalah dengan metode pemetaan perilaku (behavioral mapping) dan metode simulasi dengan menggunakan program The Sims 3 yaitu simulasi alur pergerakan manusia di dalam halte. Dari hasil  analisis ditemukan bahwa halte yang sekarang tidak memenuhi standar kebutuhan dimensi gerak manusia, maka untuk meningkatkan kualitas halte yang ergonomis dibutuhkan penataan sirkulasi yang lebih baik.Kata kunci: tata ruang sirkulasi, ergonomi, program The Sims 3
ANALOGI MUSIK-ARSITEKTUR MELALUI PROSES TRANSFORMASI PADA SIMULASI PERLUASAN GEREJA KATEDRAL BOGOR
Authors: Herliana Emmelia Tricia
Published: March 2019

The selection of appropriate approaches for specific design project is the most creative step in a design process. In the recent research report (Herliana 2010), the approach which is derived from auditorial sensation through a conceptual interpretation of the characteristics of liturgical music in the Catholic Church explores the analogy of the musical composition elements and the architectural elements of design. The aim of this study is to implement the interpretation of the analogous of musical composition elements to the simulation in designing the extension of Cathedral Church in Bogor. The synthetic process explores a new configuration pattern of form and space - through the superimposition method of site-pattern interpretation and sound-pattern interpretation - to create a new order. The result is the re-arrangement of the form and space configuration through the process of creating “musical composition” in site, such as maintaining the hierarchy of site and the building structure, creating melodies, elaborating modulations, giving the ornaments, adding accents, and making rhyme; by strengthening dominant patterns and weakening sub-dominant patterns.Keywords: conceptual interpretation, analogy in Architecture, musical elements, superimposition methodAbstrak: Proses pencarian dan pemilihan pendekatan yang paling tepat untuk suatu kasus proyek yang spesifik adalah tahap yang memerlukan kreatifitas dan paling menentukan di dalam proses merancang. Pada artikel hasil penelitian penulis (Herliana 2010), telah disebutkan mengenai pendekatan yang bersumber dari sensasi bunyi melalui interpretasi konseptual karakteristik musik liturgi pada Gereja Katolik untuk merumuskan analog dari unsur-unsur komposisi musikal terhadap unsur-unsur arsitektural pada perancangan perluasan Gereja Katedral. Tulisan yang merupakan hasil penelitian mengenai proses desain ini bertujuan untuk menerapkan analog-analog dari unsur komposisi musikal pada simulasi perancangan perluasan bangunan Gereja Katedral di Bogor. Proses sintesis dilakukan dengan mencari konfigurasi ruang dan bentuk yang baru melalui metoda superimposisi dari interpretasi pola lahan dan interpretasi pola bunyi yang terjadi pada lahan untuk menciptakan keteraturan. Hasilnya adalah penataan ulang terhadap konfigurasi ruang dan bentuk melalui proses menciptakan “komposisi musikal” pada lahan, seperti dengan mempertahankan hirarki ruang pada struktur bangunan dan “site”, pembentukan melodi, pengolahan modulasi, pemberian ornamen, menambahkan aksen, dan membuat syair; dengan memperkuat pola yang dominan.Kata kunci: interpretasi konseptual, analogi dalam Arsitektur, unsur-unsur musikal, metoda superimposisi
RENOVASI AKUSTIK GEDUNG KONSER PASCASARJANA INSTITUT SENI INDONESIA (PS-ISI) YOGYAKARTA
Authors: Satwiko Prasasto
Published: March 2019

Abstract: This paper reports an acoustical research project conducted as a scientific base for the renovation of the Concert Hall of Postgraduate Program, Indonesia Art Institute, Yogyakarta. The concert hall is intended mostly for classical music performances. The renovation has been limited by the form of the existing building, tight time schedule, budget, material provision as well as low labors’ skill. The research applied digital simulation method using Ecotect 5.5 and CATT v8. Testing conducted after construction process found that the simulation results could be reproduced well in the real world. The sound of the played music instrument fulfills the hall with clear details.Keywords: Classical music, acoustics, concert hall, computer simulationAbstrak: Makalah ini menyajikan hasil penelitian akustik sebagai landasan ilmiah renovasi gedung konser musik klasik Pascasarjana Institut Seni Indonesia Yogyakarta. Renovasi dibatasi oleh bentuk gedung yang sudah ada, waktu, biaya, bahan yang tersedia serta kemampuan dan keterampilan yang dimiliki oleh pekerja lokal. Metoda utama yang dipakai adalah simulasi digital dengan memakai software Ecotect 5.5 dan CATT v8. Uji coba yang dilakukan setelah proses konstruksi selesai menunjukkan bahwa hasil simulasi dapat diaplikasikan pada keadaan nyata dengan baik. Bunyi musik terasa hidup dan detail terdengar dengan baik.Kata kunci: Musik klasik, akustik, gedung konser, simulasi komputer
ANALISIS PENGARUH PEMBANGUNAN JALAN LAYANG JANTI TERHADAP PERKEMBANGAN TATA RUANG KAWASAN JANTI STUDI KASUS : KAWASAN JANTI, DESA CATURTUNGGAL, KABUPATEN SLEMAN, D. I. YOGYAKARTA
Authors: El Boru Jeky
Published: March 2019

Abstract: This research aims to analyze the impact of Janti Flyover Construction toward the growth of layout at Janti Urban Area, including structured space, open space, and linkage. Method used for data collecting are observation, air photograph monitoring, and interview, whereas the analysis method is qualitative description, which is the superimposed method of two layers, that are the layout condition before and after flyover construction. The result shows that the impact of Janti Flyover construction can be seen on building mass (solid), the increasing number of open spaces, including the road network, parking place, and park, whereas the relation between spaces, visually and structurally, can be seen on the growth of buildings which have new shapes and styles, therefore the performance of the overall building does not have a proportional shape. Considering Janti Street at the collective relation, its role is getting stronger as the main frame road network.Keywords: Flyover construction, layout changing, Janti AreaAbstrak: Penelitian ini bertujuan untuk menganalisis pengaruh pembangunan Jalan Layang Janti terhadap perkembangan tata ruang Kawasan Janti, meliputi ruang terbangun, ruang terbuka, serta hubungan antar ruang (“linkage”). Metode pengumpulan data dilakukan melalui observasi, pengamatan foto udara, dan wawancara; sedangkan metode analisis melalui deskripsi secara kualitatif yang berupa “superimposed method” dari dua lapisan kondisi lahan, yakni kondisi tata ruang sebelum dan sesudah pembangunan jalan layang. Hasil penelitian menunjukkan bahwa pengaruh pembangunan Jalan Layang Janti terdapat pada massa bangunan (“solid”), pertambahan ruang terbuka yang berupa jaringan jalan, parkir, dan taman; sedangkan pada hubungan antar ruang ̶ secara visual dan struktural ̶ yakni tumbuhnya bangunan dengan bentuk dan gaya baru, sehingga bentuk tampilan bangunan secara keseluruhan tidak proporsional. Pada hubungan kolektif, Jalan Janti semakin kuat perannya sebagai kerangka utama jaringan jalan.Kata kunci : Pembangunan jalan layang, tata ruang, Kawasan Janti
TANTANGAN PELESTARIAN DAN PERUBAHAN TERHADAP MANFAAT RUANG TRADISIONAL AKIBAT PENGARUH KEGIATAN INDUSTRI RUMAH TANGGA; STUDI KASUS : RUMAH TINGGAL TRADISIONAL KUDUS
Authors: Tarigan Riandy
Published: March 2019

Abstrak: Perkembangan kegiatan industri kecil dan rumah tangga serta kegiatan perdagangan sangat pesat sebagai upaya masyarakat dalam memenuhi kebutuhan hidup. Kegiatan tersebut dilakukan di dalam rumah tangga karena keterbatasan modal untuk menyewa tempat untuk kegiatan industri dan perdagangan. Rumah tinggal tradisional merupakan rumah dengan berbagai konsep tradisi yang turun temurun yang diwujudkan kedalam tata ruang dan bentuk bangunan. Kebudayaan awal mula rumah sebagai fungsi hunian untuk berlindung serta sebagai citra dari nilai sosial dan budaya telah berkembang dan berubah menjadi kegiatan ekonomi-produktif. Perkembangan ini merupakan fenomena evolutif yang menarik karena berpengaruh ke dalam sistem tata ruang tradisional yang berkaitan dengan guna dan citra. Kegunaan terkait dengan perubahan fungsi dan tata ruang tradisional dan citra ruang yang diwujudkan ke dalam makna tata letak ruang tersebut terkait dengan kebudayaan. Kajian ini diarahkan kepada penelitian terhadap rumah yang mempunyai ciri  tradisional yang telah berkembang kegiatan industri. Dengan tumbuhnya kegiatan industri, secara hipotesis akan terjadi perubahan fungsi dan makna ruang untuk menyesuaikan kebutuhan terhadap kegiatan industri tersebut. Penelitian ini untuk melihat tantangan  perubahan cara pandang masyarakat terhadap makna rumah tradisional dan bagaimana penghuni mengantisipasi makna tradisional tersebut ke dalam perubahan tata ruang sebagai akibat dari adanya kegiatan industri didalamnya. Metode penelitian adalah metode deskriptif-kualitatif dengan melakukan indepth interview terhadap penghuni rumah tradisional di Kudus yang terdapat kegiatan industri dan perdagangan didalamnya. Analisa dilakukan dengan membandingkan melalui peta perubahan fungsi ruang saat ini dengan makna ruang tradsioan masa lalu. Dari analisa ini akan ditetapkan mana ruang yang mempunyai sifat dan kedudukan pola ruang tradisional  yang tetap dan yang telah berubah.  Penelitian ini bertujuan untuk mendapatkan temuan bagaimana konflik antara  perubahan kegiatan yang terjadi dalam rumah sekaligus tantangan terhadap upaya untuk melestarikan ruang tradisional tersebut yang diwujudkan dalam penataan ruang.Kata kunci : perubahan, pelestarian, ruang tradisional, kegiatan industri dan perdagangan, Kota Kudus.
‘DISPLACEMENT’, KRITERIA DEKONSTRUKSI PETER EISENMAN
Authors: Mubarrok Noor Zakiy
Published: March 2019

Abstract: The implementation of deconstruction in architecture presents an extraordinary building, that no rarely lob the name of the designer, no exception for an American architect and theorists, Peter Eisenman. ‘Displacement’ is the notion of Peter Eisenman contains some criteria to implement deconstruction in architecture. The purpose of this research is to explore the thoughts and views of Peter Eisenman about deconstruction in architecture, especially about the notion of ‘displacement’, and its application in the design.Keywords: architecture deconstruction, displacement, peter eisenman Abstrak: Penerapan dekonstruksi dalam arsitektur, menghasilkan karya arsitektur yang luar biasa, yang tak jarang melambungkan nama perancangnya, tak terkecuali Peter Eisenman, seorang arsitek dan teoritikus kebangsaan Amerika. Displacement, merupakan ide yang dicetuskan Peter Eisenman berisi kriteria-kriteria yang harus dipenuhi sebagai upaya menerapkan dekonstruksi dalam arsitektur. Tujuan dari penelitian ini adalah untuk mengeksplorasi pemikiran serta pandangan Peter Eisenman tentang dekonstruksi dalam arsitektur terutama tentang ide Displacement, serta aplikasinya pada rancangan.Kata kunci: dekonstruksi dalam arsitektur, displacement, peter eisenman
PENGEMBANGAN KONSEP PARIWISATA SUNGAI BERBASIS MASYARAKAT ; Studi Kasus: Kawasan Bantaran Sungai Gadjah Wong Yogyakarta
Authors: Tisnawati Endah , Ratriningsih Desrina
Published: March 2019

Abstract: Gajah Wong River is one of three rivers that pass through the city of Yogyakarta in the east, the length is 20 km. This river entered the city of Yogyakarta through the District Umbulharjo and Kotagede District. Gajah Wong riverside region has great potential as a river tourism area. This paper describes the effort to develop the river area into a community-based tourism area. The method used is qualitative. As a result, the diversity of river attractions, access to the area, and community participation has the potential to increase the attractiveness of the riverside area as a riverside tourism area to create community welfare.Keywords: river tourism, community-basedAbstrak: Sungai Gajah Wong merupakan salah satu dari tiga sungai yang melintas di Kota Yogyakarta di bagian timur, panjangnya 20 km. Sungai ini menembus Kota Yogyakarta melalui Kecamatan Umbulharjo dan Kecamatan Kotagede. Kawasan bantaran sungai Gajah Wong menyimpan potensi besar sebagai wisata sungai. Tulisan ini memaparkan upaya pengembangan kawasan sungai menjadi kawasan wisata berbasis masyarakat. Metode yang digunakan adalah kualitatif. Hasilnya, keragaman aktraksi sungai, akses ke kawasan, dan partisipasi masyarakat berpotensi meningkatkan daya tarik kawasan sebagai kawasan wisata sungai untuk menciptakan kemakmuran masyarakat.Kata Kunci: wisata sungai, berbasis masyarakat.
SETING ALAMI SEBAGAI SARANA ANAK UNTUK MENGATASI TEKANAN LINGKUNGAN DI KAMPUNG KOTA
Authors: Sativa Sativa , Setiawan Bakti , Wijono Djoko , Adiyanti MG
Published: March 2019

Abstract: Nowadays, the majority of Indonesian people live in the dense urban kampungs. Some of those kampungs laid on the riverside, as a marginal area -- due to their low economic value of the land. They have specific conditions especially on the limitation of infrastructures and facilities for children activities in the settlement area. This research is a part of my dissertation paper, which aims to gain how children (mainly school-age children) coping with such condition. This study is a qualitative exploratory research, meanwhile, observation and interview were used as collecting data methods. Kampung Ngampilan in Yogyakarta, Indonesia, was chosen as a case area, because of its unique characteristics: located on the riverside of Winongo River, had a high density, and most people have low economics. As the result, this study found that natural setting, especially river area and its surrounding vegetation, is a focus location for children to release live stress in their settlement, due to two space aspects: thermal comfort and visual comfort. This condition was triggered by the limited area of their house so that the children prefer to go out from their house especially after attending school in the afternoon. This results will be useful as a reference for urban kampung planning, especially in riverfront area.Keywords: children, kampung, environmental press, natural settingAbstrak: Mayoritas penduduk kota Indonesia tinggal di kampung berkepadatan tinggi. Sebagian dari kampung -kampung berada di bantaran sungai sebagai salah satu area kota yang dianggap marginal karena nilai ekonomi lahan rendah. Kampung-kampung umumnya berkondisi khas dan memiliki keterbatasan infrastruktur termasuk fasilitas untuk kegiatan anak-anak di permukiman. Studi ini merupakan bagian dari disertasi penulis, yang bertujuan mengetahui bagaimana anak-anak (terutama anak usia sekolah dasar) menghadapi tekanan lingkungan. Kampung Ngampilan dipilih karena merupakan kampung kota yang sangat padat, terletak di tepi sungai, berkontur curam, dan warganya termasuk kelompok ekonomi menengah ke bawah. Kajian ini menggunakan metode kualitatif eksploratif, dan penggalian data dilakukan dengan metode observasi lapangan dan wawancara. Penelitian menemukan, seting alami kampung, khususnya sungai dan vegetasi di sekitarnya, merupakan area pilihan utama anak bermain, karena memiliki dua aspek kenyamanan, yaitu kenyamanan termal dan kenyamanan visual. Pilihan anak-anak dipicu oleh kondisi rumah mereka yang sempit, sehingga mereka lebih memilih keluar rumah sepulang sekolah atau sore hari. Temuan ini dapat menjadi acuan bagi pengembangan kampung kota Indonesia yang lebih kondusif untuk anak, khususnya kampung tepi sungai.Kata kunci: seting alami, tekanan lingkungan, kampung kota, anak
PENILAIAN KONDISI FISIK RUMAH TRADISIONAL JOGLO DI KELURAHAN JAGALAN, KOTAGEDE
Authors: Kusuma Gianny Angger , Cahyandari Gerarda Ida Orbita
Published: March 2019

Abstract: Kotagede is the capital of the First Mataram Kingdom and the cultural heritage area in Yogyakarta. In the Kotagede area there are several traditional houses, namely Javanese houses, Kalang houses, and Colonial houses. In Jagalan Village, Kotagede found Joglo houses that still exist today. Joglo houses have a diverse history of ownership. Some houses are added with the arrangement of the space layout, the development of the times and the development of the activities of their owners. Joglo houses in Kotagede were mostly earthquakes due to the tectonic earthquake in 2006. An assessment of the physical condition of traditional buildings is the focus of this study. The method used is the method in this study. This study uses primary data and secondary data at three Joglo Houses in Jagalan Village, Kotagede. The three joglo houses have been subjected to repeated excavations. This study aims to maintain and preserve Joglo Traditional Houses in the Kotagede Cultural Heritage Area, precisely the Jagalan Village. Keywords: Joglo House, Jagalan, Kotagede, conservationAbstrak: Kotagede adalah ibukota Kerajaan Mataram pertama dan kawasan cagar budaya di Yogyakarta. Di dalam kawasan Kotagede terdapat beberapa rumah tradisional yaitu rumah Jawa, rumah Kalang, dan rumah Kolonial. Pada Kelurahan Jagalan, Kotagede terdapat rumah-rumah Joglo yang masih ada hingga saat ini. Rumah-rumah Joglo memiliki sejarah kepemilikan yang beragam. Beberapa rumah mengalami perubahan dan penambahan tata letak ruang, mengikuti perkembangan zaman dan perkembangan aktivitas pemiliknya. Rumah-rumah joglo di Kotagede sebagian besar direnovasi akibat gempa tektonik tahun 2006. Penilaian kondisi fisik bangunan-bangunan tradisional yang mengalami renovasi menjadi fokus penelitian ini. Metode kualitatif adalah metode yang digunakan dalam penelitian ini. Penelitian ini menggunakan data primer dan data sekunder pada tiga Rumah Joglo di Kelurahan Jagalan, Kotagede. Ketiga rumah joglo sudah mengalami renovasi berulang kali. Penelitian ini bertujuan untuk mempertahankan dan melestarikan Rumah tradisional Joglo pada Kawasan Cagar Budaya Kotagede, khususnya Kelurahan Jagalan.Kata kunci: Rumah joglo, Jagalan, Kotagede, konservasi
PANDANGAN PEMILIH PEMULA TERHADAP PEMILIHAN UMUM DI INDONESIA (Kajian terhadap pandangan siswa SMA Pangudi Luhur Van Lith Muntilan terhadap Pemilu Legislatif dan Pemilu Presiden)
Authors: Hartono Y. , Putri E.Mery Christian
Published: March 2019

INTISARIPenelitian ini hendak menganalisis bagaimana Pandangan Pemilih Pemula Terhadap Pemilihan Umum Di Indonesia. Penelitian ini adalah penelitian juridis empiris yang hendak mengamati dan menganalisis pandangan pemilih pemula terhadap pemilu lagislatif dan pemilu presiden. Responden yang dimintakan pandangan adalah seluruh siswa yang baru pertama kali memiliki hak pilih karena telah memenuhi syarat dari segi usia. Mendasarkan pada analisis, dapat disimpulkan bahwa; sebagian besar siswamemahami bahwa pemilihan umum dengan segala aspek-aspeknya dalam rangka memilih anggota legislatif dan presiden pada tahun 2014 ini merupakan sarana demokrasi dengan alasan-alasan yang menunjukkan aspek-aspek penting dalam negara demokrasi. Sebagian besar siswa juga memandang bahwa anggota legislatif (DPR, DPD dan DPRD) dan presiden yang ada sekarang belum mampu melaksanakan tugas dan fungsinya seperti yang diharapkan. Meskipun demikian, sebagian besar siswa yang semuanya adalah pemilih pemula memastikan akan menggunakan hakpilihnya dalam pemilihan umum legislatif maupun pemilihan umum presiden(66,86%) yang jumlahnya bisa bertambah mengingat masih ada 16.87 % yang belum menentukan pilihan. Rekomendasi yang dapat diberikan, adalah bahwa perlu dilakukan pendidikan politik secara lebih intensif di kalangan siswa, utamanya di SMA Pangudi Luhur Van Lith, baik secara formal melalui pelajaran di kelas, maupun secara informal dengan pembelajaran ke lembaga-lembaga legislatif atau mendatangkan praktisi sehingga siswa mengetahui secara empiris kinerja wakil-wakil rakyat guna mendapatkan pemahaman dan gambaran yang lebih faktual. untuk meningkatkankinerjanya pada penyelenggaraan pemilu yang akan datang, khususnya pada tahap pendaftaran pemilih dan penentuan pemilih tetap, sehingga tidak menghilangkan hak konstitusional warga negara dalam menggunakan hak pilihnya. Hal ini sangat penting untuk mewujudkan legitimasi yang kuat bagi wakil rakyat atau presiden terpilihKata Kunci: Pandangan, Pemilih Pemula, Pemilu Legislatif, Pemilu Presiden