bluuebunny/crossref_metadata_2025 huggingface dataset:
Armazenamento de sementes de Mimosa ophthalmocentra Mart. Ex. Benth em diferentes embalagens e ambientes no Cariri Paraibano.
Authors:   , Bezerra de Freitas Valéria
Published: May 2023

A Mimosa ophthalmocentra Mart. ex Benth. pertencente a família Fabaceae, é facilmente encontrada no Bioma Caatinga e possui grande importância econômica pelo seu potencial energético. No entanto, ainda são escassos estudos relacionados com a qualidade fisiológica de suas sementes, por isso, são considerados de grande importância estudos que promovam o conhecimento do ciclo biológico das espécies nativas, pois permitirão uma melhor compreensão de como estas se comportam. Portanto, o objetivo da pesquisa foi estudar a qualidade fisiológica e o armazenamento de sementes de jurema de imbira (Mimosa ophthalmocentra Mart. ex Benth), previamente selecionadas na região do cariri Paraibano. O trabalho foi realizado no Laboratório de Ecologia e Botânica e no Laboratório de Anato- fisiologia Vegetal (CDSA/UFCG). As sementes foram coletadas de matrizes localizadas no município de Sumé-PB e levadas para o laboratório, onde foram homogeneizadas, e acondicionadas em diferentes embalagens (saco de papel do tipo Kraft e embalagem plástica) e armazenadas em ambientes de laboratório (sem controle da temperatura e umidade relativa do ar) e frezzer (condições controladas de temperatura e umidade), por um período de sete meses. Em cada mês de armazenamento foram avaliados os seguintes parâmetros: teor de água, emergência, índice de velocidade de emergência, comprimento e massa seca de plântulas. Assim, foi possível verificar que, durante o armazenamento, os ambientes e embalagens influenciaram na diminuição do vigor das sementes, onde a redução foi mais acentuada quando as sementes estavam acondicionadas em embalagem de papel em ambiente de laboratório, aumentando a velocidade da sua deterioração. Já quando as sementes estavam acondicionadas em embalagem plástica (PET) em ambiente controlado de umidade e temperatura, observou-se um melhor comportamento da sua viabilidade. Deste modo, a melhor condição para a conservação das sementes foi obtida na embalagem plástica e em ambiente freezer durante um período de 180 dias.
Fenologia de Cenostigma pyramidale (Tul.) Gagnon & G.P.Lewis em Sistema Ecológico de Caatinga no Cariri Ocidental Paraibano.
Authors:   , Alexandre da Silva Jessica
Published: May 2023

Considerando a importância dos estudos relacionados a fenologia para a definição do comportamento de espécies vegetais e dos seus ecossistemas, objetivou-se com este trabalho avaliar as fenofases de Cenostigma pyramidale (Tul.) Gagnon & G.P.Lewis em uma área de Caatinga no Semiárido paraibano. O estudo foi realizado no Espaço Experimental Reservado para Estudos de Ecologia e Dinâmica da Caatinga – Área I do Laboratório de Ecologia e Botânica – LAEB/CDSA/UFCG (7°39’38.8’’ S e 36°53’42.4’’ W; 538 m de altitude). Este espaço possui uma área de 1,05ha e nele foram dispostas 96 parcelas de 10 X 10m. Para o monitoramento das fenofases da espécie buscou-se identificar um indivíduo por parcela, entretanto, considerando que duas parcelas não tiveram a ocorrência da espécie, foram selecionados no total 94 indivíduos. Os monitoramentos foram realizados mensalmente no período de março de 2019 a fevereiro de 2020, registrando-se dados de brotamento, senescência, botão floral, floração e frutificação. Foram analisados o percentual de intensidade de Fournier e o índice de atividade. No período de monitoramento a fenofase de brotamento apresentou maior intensidade quando se evidenciou o aumento gradativo da precipitação. Considerando a fenofase de senescência esta teve os maiores picos da intensidade evidenciado nos meses outubro, novembro e dezembro/2019 sendo estes meses apresentando ausência ou níveis reduzidos de precipitação. No comportamento das fenofases de botão floral e floração, observou-se na intensidade que ocorreu um sincronismo entre essas fenofases, expressando-se praticamente iguais em todos os meses de monitoramento. Relacionado a frutificação, a maior intensidade ocorreu em abril/2019, sendo que no mesmo mês a precipitação também alcançou o maior valor. Quanto ao índice de atividade para brotamento, entre janeiro e fevereiro de 2020 todos os indivíduos expressaram esta fenofase. Nos meses de junho/2019 a outubro/2019 foi observado o maior sincronismo da fenofase de senescência, desta forma, foi constatado que 100% dos indivíduos expressaram esta atividade durante o início do período seco. O pico de atividade das fenofases botão floral e floração, ocorreu em abril/2019, quando observou-se o maior registro de precipitação. A frutificação teve maior índice de atividade em abril/2019. Portanto, foi observado que a precipitação possui grande influência sobre os eventos fenológicos, especialmente, os reprodutivos, os quais possuem maior exigência desse recurso.
Estudo etnobotânico de plantas medicinais em cinco comunidades rurais do município de Ouro Branco / RN.
Authors:   , Hidalina de Lucena Eva
Published: May 2023

LUCENA, Eva Hidalina de. Estudo etnobotânico de plantas medicinais em cinco comunidades rurais do município de Ouro Branco / RN. 2023. 36f. (Trabalho de Conclusão de Curso – Monografia), Curso Superior de Tecnologia em Agroecologia, Centro de Desenvolvimento Sustentável do Semiárido, Universidade Federal de Campina Grande, – Sumé - Paraíba – Brasil, 2023.
Superação de dormência em sementes de Mimosa ophthalmocentra Mart. Ex Benth. Durante o armazenamento.
Authors:   , Alexandre da Silva Viviane
Published: May 2023

A utilização de técnicas apropriadas para superação de dormência tegumentar presentes nas sementes são considerados de grande importância, pois permitem a obtenção do aumento da capacidade germinativa. Assim, tem-se como objetivo determinar o melhor método para superação da dormência de sementes de Mimosa ophthalmocentra Mart. ex Benth. previamente selecionadas durante o armazenamento. O trabalho foi realizado no Laboratório de Ecologia e Botânica e no Laboratório de Anato-fisiologia Vegetal (UFCG-CDSA). As sementes foram coletadas de matrizes no município de Sumé-PB no Sítio Riacho das Porteiras. Em seguida levadas para o laboratório, foram homogeneizadas, acondicionadas em garrafa PET e armazenadas em freezer (Condições controladas, a 5°C e 15°C) por um período de 90 dias. Para os testes de dormência foram utilizados quatro tratamentos pré-germinativos: T1: Testemunha – sementes intactas; T2: escarificação manual em lixa no 80 oposta ao hilo e em seguidas as sementes foram embebidas em água por um período de 24h; T3: escarificação manual em lixa no 80 oposta ao hilo e T4: Desponte – realizado o corte no lado oposto ao hilo com o auxílio de uma tesoura. Foram avaliados a emergência (%), índice de velocidade de emergência, comprimento de plântulas (cm) e massa seca de plântulas. O delineamento experimental foi instalado em delineamento inteiramente casualizado, em quatro repetições de vinte e cinco sementes para cada teste. Verificou-se após o armazenamento que o desponte (T4) e a escarificação com lixa (T3) foram os tratamentos que promoveram os melhores resultados para os parâmetros avaliados com valores de emergência 96% e 94%; IVE de 1,92 e 1,8; comprimento de plântulas de 15,1cm e 12,6cm e massa seca 12,5g e 11,6g, respectivamente. Assim, o desponte e a escarificação com lixa 80 são considerados métodos adequados para a superação da dormência de sementes de M. ophthalmocentra na região do cariri paraibano.
Discourse Marker in Research Seminar
Authors: Pujalinda Mandarsari  , Fredy Akbar K
Published: May 2023

Discourse markers is a word or a phrase that useful in communication. This paper investigates the use of discourse markers in research seminar. The objectives of this study are to find out the types and the functions of Discourse Markers used by the participants in the research seminar. The researcher analyzed the use of discourse markers based on Brinton Theory that are Brinton’s Inventory and Brinton’s Function Inventory. The results of the study contain two finding. First, there are eleven types of DMs that found based on Brinton’s Inventory, they are well, okay, and, if, but, because, I mean, oh, right, so and yes (DM yes is in Indonesian form like iya and in south Sulawesi form that is iye.). While, DMs that does not contain in Brinton’s Inventory, that is DM ya. Second, the function of discourse markers used by participants in research seminar have several functions that is based on the context. Based on Brinton’s Function Inventory, there are two function of discourse markers are textual function and interpersonal function.
Keywords: Brinton theory, discourse markers, research seminar
YouTube-Based Materials: Students’ Perception in English Listening Classroom
Authors: Syaripuddin Rahmatullah , Roni  , Rasyid Asriadi
Published: May 2023

Half of the students had difficulty mastering their English listening skills because the instructional facilities did not adequately cover the learning process and the media and method were uninteresting. This study aims to find out students’ perceptions toward the use of YouTube applications implemented in teaching English listening. The sample of the study was Biological students of Universitas Muhammadiyah Parepare, Indonesia. The research instrument used was a questionnaire consisting of three indicators. The indicators measured to know the students' perception were the module, video clips, and materials. Microsoft Excel was used to analyze the data and interpreted using a Likert scale. The result showed that the students' positive perception toward the use of the YouTube application was a very good value. The students' distorted perceptions also showed a very good category. In conclusion, youtube-based material was a very good medium for teaching Listening skills.
Keywords: YouTube Application, Students’ Perception, English Listening Skill
Authentication of Medicinal Chemicals in Traditional Herbal Products (Jamu) by UV-Vis Spectrophotometry
Authors: HUSAIN Fadli , YSRAFİL Ysrafil , DAUD Rizka Pusji Astuti , AISYAH Andi Nur , FADRI Alfat , NUR Syamsu
Published: May 2023

Traditional medicine "Jamu" is becoming very popular used by the community as an alternative treatment that can minimize side effects. However, it is profitable for manufacturers who are not responsible for herbal products by adding medicinal chemicals (BKO) to traditional herbal products. The samples used in this study were samples of traditional herbal medicine coded A1, A2; B1, B2; C1, C2; D1, D2; E1, E2; and F1, F2, which were analyzed qualitatively and quantitatively using thin-layer chromatography (TLC) and UV-Vis spectrophotometry. Based on the results obtained from the analysis using the TLC method, the herbal samples with code A1 A2 had a staining profile, Rf value, and chromatographic peak that were almost the same as the comparison standard for sodium metamizole with levels of 51.99% (A1) and 53.06% (B). the herbal medicine samples with codes B1, B2, and C1, C2 had stain profiles, Rf values, and spectrophotometric chromatography peaks that were almost the same as the comparison standard for paracetamol with paracetamol levels contained in the “Jamu” samples of 81.31% (B1), 81.66% (B2), 89.59% (C1) and 81.62% (C2). The results obtained from this study can be concluded that the samples of traditional herbal products with codes A1 and A2 contain sodium metamizole with levels of >50%. Samples of traditional herbal products B1, B2, C1, and C2 contain paracetamol with paracetamol levels contained > 50%, while the traditional herbal medicine samples with codes D1, D2, E1, E2, F1, and F2 have been identified as containing no medicinal chemicals in the traditional herbal medicine samples.
Novel treatment strategies for Triple-negative breast cancers: A comprehensive review
Authors: NAİK Jivika , KUCHEKAR Bhanudas , KUCHEKAR Ashwin , PUJARİ Rohini
Published: May 2023

Breast cancer has remained a serious health concern globally for women despite the healthcare advances which have enabled early diagnosis and treatment. Due to its metastatic ability and development of resistance to chemotherapies, triple-negative breast cancer is an extremely challenging subtype to treat. Targeted and optimized therapy is imperative as these tumors have higher recurrence rates than other types of breast cancers. This review is focused on the novel therapeutic strategies that have been proposed for the treatment of these aggressive cancers including alternative approaches like patient selection using biomarkers, metabolic reprogramming and development of smart drug delivery systems (SDDS) using targeted nanoparticles to treat the tumors as well as ensure prevention of recurrence. All of these approaches are aimed towards removing and treating the malignancies of triple-negative breast cancer (TNBC) and optimizing the therapies according to the patient cohorts. Further research is, however, necessary for the designing of an effective therapeutic regimen for patient sub-groups suffering from TNBC.
Öksüz İlaçlar ve Öksüz İlaçların Yeni İlaç Geliştirilmesindeki Yeri
Authors: TARI Özden , AKKAL Adem
Published: May 2023

Son yıllarda yeni ilaç geliştirme çalışmaları kapsamında yapılan araştırmalarda, öksüz ilaçların çok önemli bir yerinin olduğu görülmektedir. Öksüz ilaçların geliştirilmesiyle, nadir hastalıkların tedavisinde kullanılacak yararlı yeni ilaçların elde edilmesi mümkün olabileceği gibi, etkinliği kanıtlanmış bu ilaçların, henüz tedavisi mümkün olmayan pek çok hastalığın tedavisi için de öncü olması beklenmektedir. Bu çalışmada, öksüz ilaçların, mevcut durumuna ilişkin araştırma ve değerlendirme yapılması amaçlanmıştır. Çalışma kapsamında yapılan literatür taramaları sonucunda, öksüz ilaçlar hakkında yaşanan son gelişmeler ve bu ilaçlarla ilgili araştırma-geliştirme çalışmalarının artmasını sağlayan yasa ve programlar detaylı olarak sunulmuştur. Öksüz ilaçlarla ilgili sunulan sayısal veriler, bu ilaçların yeni ilaç geliştirilmesindeki yerinin önemini göstermektedir.
The Leadership Knowledge Among School Principals on Teacher’s Work Discipline
Authors: Ismail Mohd Zukifli , Md Rami Ahmad Aizuddin , Muhamad Mohd Mokhtar , Abdul Aziz Nor Azni
Published: May 2023

This study was to examine the principal's leadership level of understanding on the teacher's work discipline in one school at Federal Territory of Labuan, Malaysia. A total of 131 people were included in the sample, which included all teachers in one school at Federal Territory of Labuan, Malaysia. A series of questionnaires adapted from prior research that cover the scope of this investigation, as well as survey questions generated based on operational definitions and literature reviews, were employed in this study. The most common approaches to analyzing the research objective are descriptive analysis and factor analysis. The results showed that there is a significant relationship between the level of knowledge of the principal's leadership and the teacher's discipline on demography. The implications of this study are to identify the level of knowledge of teachers regarding the ethics of the teaching profession and the discipline of teachers working within the organization. This will help the relevant parties in organizing each mechanism to further enhance the knowledge level of the principal's leadership in the profession. This study is still relevant today and will be carried out in the future with increasing issues such as integrity and value in the teaching profession.
Biztonságra törekvő betegellátás
Authors: Mikos Borbála , Tamásné Bese Nóra , Sebők Ibolya , Závodi Edit , Velkey György János
Published: May 2023

Az egészségügyi ellátás során számos betegbiztonságot veszélyeztető tényező ronthatja a betegség kimenetelét. Bár a teljes biztonságra törekvés utópisztikus, azonban a tevékenységben bekövetkező hibák, nemmegfelelőségek, kockázatok döntő többsége proaktív cselekvési tervvel kiküszöbölhető. A menedzsment technikák következetes működtetése szignifikánsan javítja mind a betegek, mind az ellátók biztonságát, egyben költséghatékony. A közlemény a Magyarországi Református Egyház Bethesda Gyermekkórházában folyó gyógyító tevékenység során alkalmazott egyes betegségbiztonsági módszerek mellett a génpótló terápia kockázatának csökkentésére irányuló programját ismerteti.
Egészségügyi végzettségű intézményvezetők arányának vizsgálata a hazai szociális idősellátásban
Authors: Schutzmann Réka , Kozák Anna , Járay Márton
Published: May 2023

Tanulmányunkban egy, a hazai szociális ágazat intézményvezetői körében végzett vizsgálat eredményeiről számolunk be az egészségügyi végzettséggel rendelkező szociális intézményvezetőkre fókuszálva. A szociális intézményvezetők alapvető szakmai paramétereiről hazai viszonylatban rendkívűl kevés ismerettel rendelkezünk, ez az információhiány a teljes ágazati dolgozói állományra egyaránt jellemző. Eredményeink reflektálnak a szakmáról alkotott tapasztalati tudásra, miszerint a szociális vezetői állomány szakvégzettség szerinti eloszlása rendkívül heterogén, az ágazathoz kapcsolódó releváns végzettségek mellett jelentős az egészségügyi végzettségűek aránya. Elemzésünk szerint a mintába (N=547 fő) került szociális intézményvezetők több mint egy ötöde rendelkezik közép- vagy felsőfokú egészségügyi végzettséggel, közöttük pedig kiemelkedően magas a felsőfokú (főiskolai/egyetemi végzettségű) ápolók aránya. Átlagéletkoruk és munkában eltöltött éveik száma szignifikánsan magasabb a mintában szereplő eltérő végzettségű vezetőhöz képest. Az ellátástípusokat tekintve markánsan felülreprezentáltak a szociális szakellátásban, ezen belül is az idősotthonok vezetésében. Az egészségügyi szakvégzettségek ilyen fokú jelenléte a szociális vezetők körében mind az egészségügy, mind a szociális szféra szemszögéből fontos kérdéseket vet fel.
Kihívások és hajtóerők az első magyar blockbuster molekula nemzetközi fejlesztési folyamatában
Authors: Németh György , Gulácsi Gábor
Published: May 2023

A közlemény egy gyógyszer – a cariprazine – fejlesztési folyamatában keresi azokat a tényezőket, amelyek lehetővé tették, hogy egy magyar székhelyű cég a nemzetközi gyógyszerpiacokon globális sikert tudjon elérni és molekulája ún. blockbuster készítménnyé váljon. Kiindulópontja az, hogy a globális sikerhez a molekula felfedezésének, a gyógyszerkészítmény különböző terápiás indikációi fejlesztésének, továbbá a gyógyszer piaci bevezetésének és promóciójának egymásra épülő mindhárom szakaszában világszínvonalú teljesítmények szükségesek, tehát magában a fejlesztési folyamatban is. A fejlesztési folyamat farmakológiai és orvostudományi szakmai aspektusainak részleteit a közlemény nem tárgyalja, de hivatkozik rá[i]. Konklúziója, hogy a siker alapját az amerikai Forest Laboratories-zal kötött licenszbe adási és együttműködési szerződés képezte, a gyógyszer-fejlesztési kihívások teljesítéséhez, a buktatók átlépéséhez és egy kivételes siker eléréséhez pedig nélkülözhetetlen volt a gyógyszeripari környezet mélyreható ismerete és elemzése, továbbá az eredményes nemzetközi kollaboráció, a nehézségeken átlendítő csoport flow és kreativitás.
 
[i] Laszlovszky I, Barabássy Á, Németh Gy: Cariprazine, a Broad-Spectrum Antipsychotic for the Treatment of Schizophrenia: Pharmacology, Efficacy and Safety, Advances in Therapy, https://doi.org/10.1007/s12325-021-01797-5
Practices Regarding Safe Urinary Catheterization among Healthcare Workers
Authors: Aftab Amina , Jan Sadiq , Khan Sabeen , Rukh Lala
Published: May 2023

Objective: To assess the knowledge and practices regarding safe urinary catheterization among health care workers Study Design: It was a Cross sectional observational study. Methodology: Ninety two health care workers were interviewed in two hospitals from April 2022 to July 2022. A questionnaire was designed about individual and departmental practices of urinary catheterization, including the practice of hand hygiene, wearing gloves, maintaining a sterile barrier and using a non-touch gentle insertion technique and post insertion catheter care. Results: Fifty respondents were doctors, while 42 were paramedics. Hand washing and using sterile gloves were reported by 67.3% and 91.2% respectively. 71.7% cleaned the area with antiseptic but only 56.5% practiced appropriate method. 67.3% had a separate sterile catheterization tray. 68.5% respondents inserted the catheter without touching its tip. Other safety measures including arrangement of prefilled syringe for inflation of balloon (89.1%), clear visualization of urethral meatus (90%), gentle insertion (84.7%), confirmation of urine flow (86.9%), and holding the catheter in place while balloon inflation (82.6%) were variably practiced. 61.9% had mistakenly passed the catheter into vagina instead of urethra at some occasion in life. 83.6% thought it necessary to hang the urine bag on bed side for safe care, but more than 84% frequently found the urine bags on the floor in their wards. Conclusion: Safe urinary catheterization practices need to be improved. Units must develop set protocols to reduce the incidence of catheter associated morbidity. This can be achieved by continuous training and audit within the department. Keywords: urinary catheter, urinary tract infection, patient safety.
Attitude and Perception of Undergraduate Medical and Dental Students towards Problem-Based Learning in Karachi
Authors: Qamar Naqvi Syeda Saima , . Mahrukh , Zaidi Yasmeen Fatima , Akram Badar , Orakzai Gulmina Saeed , Islam Aliya
Published: May 2023

Objective: The goal of this study is to assess students' attitudes and perceptions of problem-based learning sessions. Methods: A cross-sectional survey study was conducted at Medical College of Karachi from February to May 2022 with preclinical medical and dental students. Students' attitudes towards and perceptions of problem-based learning sessions were examined using an electronic questionnaire.. SPSS 21 was used to analyze the data. Results: Overall, the students had a positive attitude towards all of the items, including self-directed learning, critical thinking, integrating basic concepts into clinical science, identifying knowledge gaps, and improved problem-solving skills. Despite the fact that PBL took a lot of time, the majority of students found PBL interesting. Conclusion: Most of the preclinical students favored PBL and believe it should be included in the curriculum alongside other teaching methods. Keywords: Problem-based learning (PBL), Medical students, Dental students, Perception, Attitude
Impact of Universal Donor History Questionnaire in Pre-Donation Deferrals a Tertiary Care Hospital Experience
Authors: Shaikh Farhan Ahmed , Noureen Aqsa , Saboor Rukhsana , . Sidrah , Ali Azhar , Memon Kiran , Aamir Kiran , Ramzan Aamir
Published: May 2023

Objective: The purpose of this research was to better understand the factors that lead to pre-donation deferral at a tertiary care hospital's Blood bank. Understanding the factors that lead donors to decline can inform more effective selection criteria. Study Design: Cross-sectional/Descriptive study Place and Duration: Diagnostic and research laboratory Liaquat university of Medical and Health Sciences Jamshoro Hyderabad. January 2022-December 2022 Methods: This study comprised of 2200 donors at blood bank of LUMHS. The UDHQ included 25 questions to assess donors' backgrounds in regards to things like injections, medicines, time since last donation, tattoos, general health, dental work, sexual relationships, malaria/T.B., surgery, jaundice, vaccination, positive viral markers, etc. Haemoglobin (Hemacue 50/Diaspect Hb with daily quality control), Heart rate/rhythm, Blood pressure, Body temperature, Weight/Height, and Jaundice were all part of the physical exam. Results: There were majority 1578 (71.7%) males and 622 (28.3%) female donors among all cases. Donors mean age was 26.12±9.88 years and mean weight was 61.3±8.49 kg. 1435 (65.2%) cases were from urban areas. Among all, 1650 (75%) donors were accepted and 550 (25%) donors were deferral. Most common cause of deferral was low hemoglobin followed by anemia, HCV, HBV, inappropriate pulse rate, low BP, jaundice, active infection, malaria, syphilis, allergy, aspirin intake, drugs, last donation, skin/eye colour and sexual relationship. There were 1870 (85%) cases of replacement donors among all cases. Conclusion: The selection of healthy blood and the reduction of donor injury will be made possible by a thorough pre-donation screening interview and physical examination. Our setup has a somewhat higher blood donor deferral rate because to stringent donor sector requirements and extra attention paid to donor selection processes. The increased replacement donor deferral rate is a result of refusals for past injection history and poor hemoglobin levels. Keywords: Donors, Deferrals, Hemoglobin, Infection, HCV
Association of Radial Artery Access with Reduced Incidence of Acute Kidney Injury in Patient Undergoing Percutaneous Coronary Intervention
Authors: Shinwari Muhammad Ikram , Khan Muhammad Idrees , Hasan Tooba , Khan Raza Muhammad , Ziyad Muhammad
Published: May 2023

Introduction: Percutaneous Coronary Intervention (PCI) is a commonly performed procedure for treating coronary artery disease. However, one of the potential complications of this procedure is Acute Kidney Injury (AKI), which can result in significant morbidity and mortality for patients. Objectives of the study: The main objective of the study is to find the association of radial artery access with reduced incidence of acute kidney injury in patient undergoing percutaneous coronary intervention. Material and methods: This was a retrospective cohort study conducted at Medical Teaching Institute-Hayatabad Medical Complex, Peshawar between January 10, 2022 and June 13, 2022. The study was approved by the institutional review board. Data were collected from electronic medical records, including demographic information, medical history, procedural details, laboratory values, and outcomes. The primary outcome was the incidence of acute kidney injury (AKI), defined as an increase in serum creatinine of ≥0.3 mg/dL or ≥50% within 48 hours after the procedure. Results: Based on a study of 300 patients undergoing cardiac catheterization, there was a significant association between the use of radial artery access and reduced incidence of acute kidney injury (AKI). The odds ratio for radial artery access was 0.59 (95% CI 0.32-1.09), indicating a lower risk of AKI with this approach. This finding is consistent with the results presented in Table 3, which also showed a lower incidence of AKI in the radial artery access group. However, the p-value for radial artery access was 0.09, indicating that this association did not reach statistical significance. Conclusion: Based on the results of the study, it can be concluded that radial artery access may be associated with a lower incidence of acute kidney injury (AKI) and fewer bleeding complications compared to femoral artery access in patients undergoing cardiac procedures such as percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG).
Probiotic Effectiveness in Children Less than Five Years Old with Perennial Allergic Rhinitis: A Randomized Controlled Trial
Authors: Qadir Abdul , Manzoor Ammara , Khan Abdul Ghaffar , . Ibrahim , Khan Zarmast , Rafique Aummara
Published: May 2023

Objective: The purpose of this study was to evaluate the effectiveness of probiotics in treating perennial allergic rhinitis in children younger than five and to compare them to cetirizine. Study Design: A randomized controlled trial Place and Duration: This study was conducted at Mohtarma Benazir Bhutto Shaheed Medical College Mirpur & Child specialist New City Teaching Hospital Mirpur AJK in the duration from July, 2022 to December, 2022. Methods: There were 160 children with allergic rhinitis had age 3-60 months were included in this study. After getting informed written consent from the parents of children detailed demographics were recorded. Symptoms of presented cases were recorded. Patients were equally divided in two groups. Group I received cetirizine in 80 cases and in group II 60 cases received probiotics LP-33 for 5-weeks. Post treatment efficacy and adverse events among both groups were compared. SPSS 23.0 was used to analyze all data. Results: Mean age of the cases was 27.6±8.53 months with mean weight 12.6±11.81 kg. among 160 children, 94 (58.8%) cases were males and 66 (41.2%) children were females. Majority 82 (51.3%) cases had nasal blocking, sneezing in 80 (50%) cases, coughing in 75 (46.9%) cases, sleeping difficulties in 72 (45%) and feeding difficulties in 69 (43.1%) cases. After 5 weeks, in group I efficacy found in 72 (90%) cases and in group II 69 (86.3%) cases showed improvement, difference was insignificant (p>0.05P).Post treatment adverse outcomes in group I was 2 (2.5%) and in group II there was no any side effect found. Conclusion: In this study, we found that probiotic (LP-33) was just as effective as cetirizine in treating perennial allergic rhinitis in children less than five years old. The study found that unlike conventional treatments, probiotics had no negative effects on children with allergic rhinitis. Keywords: Allergic Rhinitis, Probiotic, Cetirizine, Perennial, Rhinorrhea
Urdu Translation and Cross-Cultural Validation of Short Fall Efficacy Scale International
Authors: Amir Sajal , Hanif Ahsan , Javed Hafiza Rabia , Tariq Fatima , Buhari Amna , Shafique Warda , Yasmin Naila , Rafi Saimoon , Rafique Hira
Published: May 2023

Background: In 2008 a tool named Short Fall efficacy international (Short FES-I) was developed by kampen et al to assess fear of fall in older adult’s Short fall efficacy scale was consisted on seven items. It is four points Likert scale. The total score is 28 which shows the high concern of fall and 7 score shows the minimum concern of fall. Objective: The Aim of the study was to translate and validate short fall efficacy scale international in Urdu language. Methods: it was a descriptive cross-sectional study. The study was completed in 2 phases in first phase forward and backward translation process was performed according to proFaNE guidelines. Secondly, the psychometric properties of Urdu version short FES-I were statistically analyzed using a sample of 110 community dwelling older adults at 2 Private hospitals of Shahdara Lahore. Participants completed the Urdu versions of Short FES-I and ABC scale. They also performed TUG. Reliability and validity of short FES-I Urdu version was evaluated by calculating Cronbach’s alpha, intra-class correlation co-efficient and Pearson/ Spearman rank correlation co-efficient. SPSS 21 was used for data analysis. Results: Content validity analyzed by content validity index ranged from (0.92- 1). Reliability and validity of Urdu Version Short FES-I was evaluated by calculating Cronbach’s alpha (α=0.93), intra-class correlation co-efficient (ICC=0.96) and Pearson rank correlation co-efficient (p= -0.90) Short FES-I to ABC scale and to TUG scale its (P=0.82). SPSS 25 was used for data analysis. Conclusion: Urdu version of Short FES-I was designed, tested for its validity and reliability on older adults. Urdu version was linguistically accurate and acceptable. It showed good content, and convergent validity. It also presented high internal consistency and test retest reliability. As an outcome, the Urdu version of short FES-I can be useful for Urdu speaking population. Keywords: Fear of fall, fall efficacy, Urdu version, Reliability, Validity
Long-Term Outcomes of Patients Undergoing Percutaneous Coronary Intervention (PCI) for Chronic Total Occlusions
Authors: Khan Bahauddin , Khan Amir Taj , Muhammad Afnan , Sawar Shah , Rahman Fouzia , Hassan Mahmood Ul
Published: May 2023

Introduction: Percutaneous coronary intervention (PCI) is a minimally invasive procedure used to treat patients with coronary artery disease. Chronic total occlusions (CTO) occur when a coronary artery is completely blocked for more than 3 months. Objectives: The main objective of the study is to find the long-term outcomes of patients undergoing percutaneous coronary intervention (PCI) for chronic total occlusions. Material and methods: The retrospective cohort study was conducted at the Hayatabad Medical Complex in Peshawar, Pakistan from June 2019 to June 2020. The study included 384 patients who underwent PCI for chronic total occlusions. Data were collected from patient records and follow-up visits. The primary outcome of the study was all-cause mortality, while the secondary outcomes included major adverse cardiovascular events (MACE), repeat revascularization, and quality of life. Data were analyzed using descriptive statistics and survival analysis. Result: The results of the retrospective cohort study investigating the long-term outcomes of patients who underwent PCI for chronic total occlusions showed that the study included 384 patients who underwent PCI for at least one chronic total occlusion. The mean age of the patients was 60.3 years, and 76.3% were male. Conclusion: In conclusion, this study suggests that percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) can provide good long-term outcomes with an overall success rate of 87.5%.
Predilation Ballooning in High Thrombus Laden STEMIs: An Independent Predictor of Slow Flow in Patients Undergoing Emergent Percutaneous Coronary Revascularization
Authors: Uddin Imad , Waleed Muhammad , Ghaffar Shakir , Rauf Muhammad Abdur , Khan Muhammad Idrees , Khan Muhammad Ishaq
Published: May 2023

Introduction: Predilation ballooning in high thrombus-laden ST-elevation myocardial infarctions (STEMIs) is a technique used during emergent percutaneous coronary revascularization (PCI) to improve blood flow and reduce clot burden in the coronary artery. Objectives: The main objective of the study is to find the predilation ballooning in high thrombus laden STEMIs as an independent predictor of slow flow in patients undergoing emergent percutaneous coronary revascularization. Material and methods: The study was a retrospective analysis of 280 consecutive patients who underwent emergent PCI for STEMI at Hayat Abad Medical Complex. Data were collected from electronic medical records of patients who met the inclusion criteria, which were patients with STEMI who underwent emergent PCI and had high thrombus burden as assessed by angiography. Patients who did not undergo predilation ballooning or who had missing data were excluded from the analysis. The collected data included demographics, clinical characteristics, laboratory values, angiographic findings, procedural details, and outcomes. Results: The results of the study show that predilation ballooning is an independent predictor of slow flow in patients undergoing emergent percutaneous coronary revascularization for high thrombus burden STEMI in the sample of 280 patients. Data presents a comparison between two groups of patients who underwent emergent percutaneous coronary revascularization with and without predilation ballooning. The comparison is based on demographic, clinical, and angiographic characteristics, as well as postprocedure in-hospital complications and outcomes. The two groups were propensity-matched in a 1:1 ratio to account for potential confounding factors. Conclusion: In conclusion, our study suggests that predilation ballooning may be an independent predictor of slow flow in patients undergoing emergent percutaneous coronary revascularization. The comparison of demographic, clinical, and angiographic characteristics between the predilation ballooning (+) and predilation ballooning (-) groups did not reveal any significant differences, indicating that the two groups were similar in terms of baseline characteristics.
Uçak Kanadı Tasarımı, Analizi ve Yapı Elemanlarının Topoloji Optimizasyonu
Authors: KORKUT Hasan , ALTAY Meryem , AYDIN Hakan
Published: May 2023

Havacılık ve uzay endüstrisinde yapısal bir parçanın üretiminde tasarım, yük, analiz süreçlerinin eş zamanlı olarak yürütülmesi gerekmektedir. Konsept tasarım sürecinde en önemli unsur parçanın en hafif şekilde görevini yerine getirebilmesidir. Bu çalışmada uçak kanat tasarımı Catia yazılımı kullanılarak yapılmıştır, alüminyum 7050 ve HexplyAS4/8552 kompozit malzemeleri için analizler gerçekleştirilmiştir. Sonlu Elemanlar Yöntemi yaklaşımı kullanılarak Hypermesh yazılımı yardımıyla Topoloji Optimizasyonu gerçekleştirilmiştir; birçok iterasyon uygulanarak tasarımda hafifletme çalışmaları için geometrik değişikliklere karar verilmiştir. Optimizasyon sonucunda ortaya çıkan kanat geometrisi yapısal olarak analiz edilip mukavemet kontrolü yapılmıştır. Geometrinin bütünlüğünü sağlayan bağlantı elemanlarının statik hesaplamaları da gerçekleştirilmiştir. İncelenen malzemeler için müsaade edilebilir tasarım değerlerine uygun sonuçlar elde edilmiştir. HexplyAS4/8552 kompozit malzeme hafiflik açısından ön plana çıksa da kullanılabilirlik ve üretime uygunluk açısından alüminyum 7050 malzemesi seçilmiştir.
Rezension von: Kretzschmar, Robert u.a. (Hrsg.), Nichtstaatliche und audiovisuelle Überlieferung
Authors: Kozlik Andreas , Kretzschmar Robert
Published: May 2023

Robert Kretzschmar, Edgar Lersch, Eckhard Lange, Dieter Kerber (Hrsgg.), Nichtstaatliche und audiovisuelle Überlieferung. Gefährdungen und Lösungswege zur Sicherung (Werkhefte der Staatlichen Archivverwaltung Baden-Württemberg, Serie A, Bd. 8), Stuttgart (Kohlhammer) 1997. 174 S.
Rezension von: Steuer, Peter (Bearb.), Vorderösterreichische Regierung und Kammer 1753-1805, Oberamt Altdorf
Authors: Ehrmann Peter , Steuer Peter
Published: May 2023

Peter Steuer (Bearb.), Gesamtinventar der Akten und Amtsbücher der vorderösterreichischen Zentralbehörden in den Archiven der Bundesrepublik Deutschland. Vorderösterreichische Regierung und Kammer 1753-1805: Oberamt Altdorf (Veröffentlichungen der Staatlichen Archivverwaltung Baden-Württemberg, Bd. 50/5), Stuttgart (Kohlhammer) 1998. 561 S.
Rezension von: Keim, Wolfgang, Erziehung unter der Nazi-Diktatur
Authors: Ehrmann Peter , Keim Wolfgang
Published: May 2023

Wolfgang Keim, Erziehung unter der Nazi-Diktatur, Bd. 1: Antidemokratische Potentiale, Machtantritt und Machtdurchsetzung, Bd. 2: Kriegsvorbereitung, Krieg und Holocaust, Darmstadt (Primus Verlag) 1997. 218 u. 505 S.
Rezension von: Haug, Brigitte, "... auf dem neuen Turnplatz der Politik ..."
Authors: Kozlik Andreas , Haug Brigitte
Published: May 2023

Brigitte Haug, „..auf dem neuen Turnplatz der Politik..“. Turnvereine in Baden und Württemberg in der Revolution 1848/49 (Wissenschaftliche Schriftenreihe, Institut für Sportgeschichte Baden-Württemberg, Bd. 5), Schorndorf (Hofmann) 1998. 212 S., zahlr. Abb.
Rezension von: Kolb, Peter; Krenig, Ernst-Günter (Hrsg.), Vom Beginn des konfessionellen Zeitalters bis zum Ende des Dreißigjährigen Krieges
Authors: Stockert Harald , Kolb Peter , Krenig Ernst Günther
Published: May 2023

Peter Kolb, Ernst-Günter Krenig (Hrsgg.), Unterfränkische Geschichte, Band 3: Vom Beginn des konfessionellen Zeitalters bis zum Ende des Dreißigjährigen Krieges, Würzburg (Echter Verlag) 1995. 752 S., mehrere Karten, Tabellen, Schaubilder und Abbildungen.
Rezension von: Landesarchivdirektion Baden-Württemberg (Hrsg.), Der Landkreis Reutlingen
Authors: Kozlik Andreas , Landesarchivdirektion Baden-Württemberg
Published: May 2023

Der Landkreis Reutlingen. Hrsg, von der Landesarchivdirektion Baden-Württemberg (Kreisbeschreibungen des Landes Baden-Württemberg), Sigmaringen (Thorbecke) 1997. 2 Bände, 2168 S., 187 Abb., 29 Kartenbeilagen.
Rezension von: Archäologische Ausgrabungen in Baden-Württemberg 1998
Authors: Stihler Daniel
Published: May 2023

Archäologische Ausgrabungen in Baden-Württemberg 1998. Hrsg, vom Landesdenkmalamt. Baden-Württemberg, dem Archäologischen Landesmuseum, der Gesellschaft für Vorund Frühgeschichte in Württemberg und Hohenzollem und dem Förderkreis Archäologie in Baden, Stuttgart (Theiss) 1999. 312 S., 16 Farbtaf., 211 Abb.
Rezension von: van Loock, Ingeborg; Gräter, Carlheinz, Rebenlandschaften
Authors: Wieland Dieter , Loock Ingeborg van , Gräter Carlheinz
Published: May 2023

Ingeborg van Loock, Carlheinz Gräter, Rebenlandschaften, Freiburg i. Br. (Eulen Verlag Harald Gläser) 1999. 48 S., 21 Aquarelle.
Rezension von: Schneidmüller, Bernd; Weinfurter, Stefan (Hrsg.), Otto III. - Heinrich II.
Authors: Lubich Gerhard , Schneidmüller Bernd , Weinfurter Stefan
Published: May 2023

Bernd Schneidmüller, Stefan Weinfurter (Hrsg.), Otto III. - Heinrich II. Eine Wende? (Mittelalter-Forschungen, Bd. 1), Sigmaringen (Thorbecke) 1997. 438 S., 16 z. T. farbige Abb.
Rezension von: Weiß, Barbara, Das Stuttgarter Rumpfparlament
Authors: Kohl Herbert , Weiß Barbara
Published: May 2023

Barbara Weiß, Das Stuttgarter Rumpfparlament. Das Tagebuch von Emil Adolph Roßmäßler und das Selbstverständnis der Abgeordneten (Veröffentlichungen des Archivs der Stadt Stuttgart, Bd. 80), Stuttgart (Klett-Cotta) 1999. 124 S„ 10 Abb.
Rezension von: Bahn, Peter (Hrsg.), "Als ich ein Kind war ..."
Authors: Schulze Ute , Bahn Peter
Published: May 2023

Peter Bahn (Hrsg.), „Als ich ein Kind war..." Bretten 1497 - Alltag im Spätmittelalter. Begleitbuch zur Ausstellung, Übstadt-Weiher (Verlag Regionalkultur) 1997. 198 S., 89 teilw. färb. Abb.
Rezension von: Bauer, Markus, Der Münsterbezirk von Konstanz
Authors: Schulze Ute , Bauer Markus
Published: May 2023

Markus Bauer, Der Münsterbezirk von Konstanz. Domherrenhöfe und Pfründhäuser der Münsterkapläne im Mittelalter (Konstanzer Geschichts- und Rechtsquellen, NF der Konstanzer Stadtrechtsquellen, Bd. 35), Sigmaringen (Thorbecke) 1995. 335 S., 1 Plan.
Rezension von: Maisch, Andreas (Hrsg.), Die zweite Heimat
Authors: Ehrmann Peter , Maisch Andreas
Published: May 2023

Andreas Maisch (Hrsg.), Die zweite Heimat. Heimbachsiedlung und Teurershof 1949-1998 (Veröffentlichungen des Stadtarchivs Schwäbisch Hall, Bd. 6) Schwäbisch Hall (Stadtarchiv Schwäbisch Hall) 1998. 156 S., zahlr. Abb.
Rezension von: Vogel, Thomas, Fehderecht und Fehdepraxis im Spätmittelalter am Beispiel der Reichsstadt Nürnberg (1404-1438)
Authors: Pusch Alexander , Vogel Thomas
Published: May 2023

Thomas Vogel, Fehderecht und Fehdepraxis im Spätmittelalter am Beispiel der Reichsstadt Nürnberg (1404-1438) (Freiburger Beiträge zur mittelalterlichen Geschichte, Bd. 11), Frankfurt (Peter Lang Verlag) 1998. 324 S.
Rezension von: Gräter, Carlheinz; Lusin, Jörg, Steinkreuz und Bildstock in Kunst und Literatur
Authors: Göpfert Eberhard , Gräter Carlheinz , Lusin Jörg
Published: May 2023

Carlheinz Gräter, Jörg Lusin: „dem got genat“ – Steinkreuz und Bildstock in Kunst und Literatur. Würzburg (Echter) 2008. 125 S., Abb.
Rezension von: Rückert, Maria Magdalena (Hrsg.), Württembergische Biographien unter Einbeziehung hohenzollerischer Persönlichkeiten Bd. II
Authors: Beutter Wilfried , Rückert Maria Magdalena
Published: May 2023

Württembergische Biographien unter Einbeziehung hohenzollerischer Persönlichkeiten. Bd. II. Im Auftrag der Kommission für geschichtliche Landeskunde in Baden-Württemberg hg. von Maria Magdalena Rückert . Stuttgart (Kohlhammer) 2011. 358 S.
Rezension von: Krumrein, Frieder, Suhlburg und Wittighausen
Authors: Beutter Wilfried , Krumrein Frieder
Published: May 2023

Frieder Krumrein: Suhlburg und Wittighausen. Hofgeschichten aus 2 Weilern der Gemeinde. Mit Beiträgen von Horst Jäger. Hg. vom Kultur- und Förderverein Rößler-Museum Untermünkheim e. V. (Untermünkheimer Ortsgeschichte Bd. 6). 2010. 189 S., zahlr. Abb.
Rezension von: Behr, Hartwig, Der Verlust der Residenz und der Weg zum Weltbad
Authors: Bittel Christoph , Behr Hartwig
Published: May 2023

Hartwig Behr: Der Verlust der Residenz und der Weg zum Weltbad. Skizzen zur Geschichte Bad Mergentheims. Mit einem Geleitwort von Dr. Thomas Schnabel, Leiter des Hauses der Geschichte Baden-Württemberg. Bad Mergentheim (Verein Deutschordensmuseum Bad Mergentheim e.V.) 2010. 66 S., 51 Abb.
Rezension von: Beutter, Herta (Hrsg.), Der Panoramamaler Louis Braun (1836–1916)
Authors: Glück Christa , Beutter Herta
Published: May 2023

Der Panoramamaler Louis Braun (1836–1916). Vom Skizzenblatt zum Riesenrundbild. Hg. vom Historischen Verein für Württembergisch Franken e.V. und dem Förderkreis Hällisch- Fränkisches Museum e.V. – Schwäbisch Hall (Mahl) 2012. 240 S., zahlr. Abb., teilw. farbig.
Rezension von: Maisch, Andreas (Hrsg.), Schwäbisch Hall 1914-1918
Authors: Brehmer Jörg , Maisch Andreas
Published: May 2023

Andreas Maisch (Hrsg.): Schwäbisch Hall 1914-1918. Eine Stadt und ihre Region im Ersten Weltkrieg. Schwäbisch Hall (Verlagsdruckerei Schmidt) 2014. 556 S., zahlr. Abb.
Specifics of Energy Management in the Republic of Moldova
Authors: Suslenco Alina , Corbu Viorel
Published: May 2023

This study analyses the management specifics of the enterprises in the energy sector of the Republic of Moldova, as well as elucidates the most pressing problems and challenges they face. Thus, the purpose of this article is to analyse the specifics of energy management in the Republic of Moldova. The methodology of the research is focused on the use of theoretical analysis, gravitating with the epicentre towards empirical research, whose specific is a qualitative one, characteristic of content analysis. As a result of the observations made, we can mention that the energy management in the Republic of Moldova is deficient and very complex, given that in this field, in the last 20 years (2001-2021), very few changes have been made that would have positively influenced its development.
Visiones constitucionales de la Organización Mundial del Comercio: entre el desarrollo, el libre mercado y la marginalidad. El caso de Colombia
Authors: Parra Rosas Juan Felipe , Cumbe Figueroa Alexandra , Jaramillo Vargas Diego Andres
Published: May 2023

Este artículo presenta al lector un análisis de la norma de segundo plano que utiliza la Corte Constitucional colombiana cuando menciona y recurre a las fuentes de la Organización Mundial del Comercio (OMC) en sus fallos. Siendo esto examinado a la luz de dos marcos conceptuales: “la Síntesis del Siglo xx” y las “reglas de fondo que condicionan” la resolución de un caso.  Para ello, a través de la metodología de revisión jurisprudencial, analizamos 60 sentencias de constitucionalidad proferidas por la Corte Constitucional Colombiana entre 1995 y 2022, en las que existía una mención directa a la OMC. Dentro de esta búsqueda encontramos que de los 60 fallos únicamente 19 fallos mencionan a la OMC en su raciocinio de manera central o al menos utilizan alguna de sus fuentes o consideraciones normativas para sustentar las decisiones tomadas. En nuestros hallazgos encontramos que la mención a la OMC es utilizada por la Corte para justificar y respaldar constitucionalmente el libre mercado que, bajo una premisa de ausencia de ejercicios de poder, se comprende como un proyecto económico que promueve y fortalece el desarrollo social y económico de los Estados.
Los factores subyacentes y la probabilidad de medidas sanitarias y fitosanitarias del sector agropecuario del Perú notificadas a la Organización Mundial del Comercio
Authors: Valverde Arevalo Marcelo Alonso
Published: May 2023

Previamente se han identificado una serie de determinantes de la actividad regulatoria de asuntos sanitarios y fitosanitarios, tales como las capacidades científicas, legales, la producción nacional, entre otros. Si bien las principales determinantes se orientan a aspectos regulatorios, no es posible descartar que sean utilizadas como barreras al comercio.

En el caso del Perú, siendo uno de los Miembros de la OMC que más notificaciones ha emitido, no se ha analizado previamente los factores subyacentes relacionados a este tipo de medidas. En ese sentido, mediante modelos Probit y Logit se ha podido identificar los factores que inciden en la probabilidad de que el Perú notifique medidas sanitarias y fitosanitarias. Los resultados indican que, contrariamente a lo esperado, en el caso peruano el aumento de las capacidades científicas y legales generarían una menor cantidad de medidas sanitarias. Esto sugeriría que este país aplica más medidas de las necesarias, pudiendo ser utilizadas como barreras al comercio.