bluuebunny/crossref_metadata_2025 huggingface dataset:
Factors Associated with Days Alive and at Home within 30 Days (DAH30) Scores Following Surgery: A Systematic Review
Authors: Bartyn Jenna , Morkaya James , Karunaratne Sascha , Chen Tian You , Solomon Michael , Koh Cherry , Sandroussi Charbel , Steffens Daniel
Published: October 2024

Background/Objectives: Days Alive and at Home within 30 days (DAH30) is a patient-centred measurement tool designed to assist with the decision-making and management of patients undergoing surgery. Thus, identifying factors associated with better DAH30 scores would support healthcare providers to optimise patient care and outcomes. This systematic review aimed to determine factors associated with DAH30 scores following surgery. Methods: A sensitive electronic search was conducted in MEDLINE, Embase, Scopus, Web of Science and CINAHL databases in September 2022. Eligible studies included patients undergoing surgery and reporting the association of preoperative and/or postoperative factors and DAH30. Risk of bias was assessed using the QUIPs tool. Results: Of the 14 studies identified, the majority (n = 13, 93%) were cohort studies, presenting moderate or high (n = 8, 60%) risk of bias. This review identified a number of factors influencing DAH30 scores in patients undergoing surgery. ASA Physical Status and surgery duration were the most common factors influencing DAH30 scores. Conclusions: Optimising patients’ health prior to surgery and reducing surgical time have the potential to improve patients’ recovery.
Inhibitory Effects of Reynoutria japonica Houtt. on Pain and Cartilage Breakdown in Osteoarthritis Based on Its Multifaceted Anti-Inflammatory Activity: An In Vivo and In Vitro Approach
Authors: Jo Hee-Geun , Baek Chae Yun , Lee Juni , Hwang Yeseul , Baek Eunhye , Song Aejin , Song Ho Sueb , Lee Donghun
Published: October 2024

In the past 30 years, the number of years lived with disability due to osteoarthritis (OA) has doubled, making it an increasing global health burden. To address this issue, interventions that inhibit the progressive pathology driven by age-related low-grade inflammation, the primary mechanism of OA, are being actively pursued. Recent investigations have focused on modulating the age-related low-grade inflammatory pathology of this disease as a therapeutic target. However, no agent has successfully halted the disease’s progression or reversed its irreversible course. Reynoutria japonica Houtt. (RJ), a promising East Asian herbal medicine, has been utilized for several diseases due to its potent anti-inflammatory activity. This study aims to determine RJ’s capacity to inhibit OA symptoms and associated inflammation, exploring its potential for further development. In vivo and in vitro experiments demonstrated RJ’s anti-OA activity and modulation of multifaceted inflammatory targets. RJ significantly inhibited pain, gait deterioration, and cartilage destruction in a monosodium iodoacetate-induced OA rat model, with its analgesic effect further confirmed in an acetic acid-induced writhing model. RJ exhibited consistent anti-inflammatory activity against multiple targets in serum and cartilage of the OA rat model and lipopolysaccharide-induced RAW 264.7 cells. The inhibition of inflammatory cytokines, including interleukin-1β, interleukin-6, matrix metalloproteinase-13, tumor necrosis factor-α, and nitric oxide synthase 2, suggests that RJ’s alleviation of OA manifestations relates to its multifaceted anti-inflammatory activity. These results indicate that RJ merits further investigation as a disease-modifying drug candidate targeting OA’s inflammatory pathology. To further characterize the pharmacological properties of RJ, future studies with expanded designs are warranted.
Exploring the Antibacterial and Antiparasitic Activity of Phenylaminonaphthoquinones—Green Synthesis, Biological Evaluation and Computational Study
Authors: Lopez-Mercado Sussan , Enríquez Cinthya , Valderrama Jaime A. , Pino-Rios Ricardo , Ruiz-Vásquez Liliana , Ruiz Mesia Lastenia , Vargas-Arana Gabriel , Buc Calderon Pedro , Benites Julio
Published: October 2024

Organic compounds with antibacterial and antiparasitic properties are gaining significance for biomedical applications. This study focuses on the solvent-free synthesis (green synthesis) of 1,4-naphthoquinone or 2,3-dichloro-1,4-naphthoquinone with different phenylamines using silica gel as an acid solid support. The study also includes in silico PASS predictions and the discovery of antibacterial and antiparasitic properties of phenylaminonaphthoquinone derivatives 1–12, which can be further applied in drug discovery and development. These activities were discussed in terms of molecular descriptors such as hydrophobicity, molar refractivity, and half-wave potentials. The in vitro antimicrobial potential of the synthesized compounds 1–12 was evaluated against a panel of six bacterial strains (three Gram-positive: Staphylococcus aureus, Proteus mirabilis, and Enterococcus faecalis; and three Gram-negative bacteria: Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae). Six compounds (1, 3, 5, 7, 10, and 11) showed better activity toward S. aureus with MIC values between 3.2 and 5.7 μg/mL compared to cefazolin (MIC = 4.2 μg/mL) and cefotaxime (MIC = 8.9 μg/mL), two cephalosporin antibiotics. Regarding in vitro antiplasmodial activity, compounds 1 and 3 were the most active against the Plasmodium falciparum strain 3D7 (chloroquine-sensitive), displaying IC50 values of 0.16 and 0.0049 μg/mL, respectively, compared to chloroquine (0.33 μg/mL). In strain FCR-3 (chloroquine-resistant), most of the compounds showed good activity, with compounds 3 (0.12 μg/mL) and 11 (0.55 μg/mL) being particularly noteworthy. Additionally, docking studies were used to better rationalize the action and prediction of the binding modes of these compounds. Finally, absorption, distribution, metabolism, excretion, and toxicity (ADMET) predictions were performed.
The Expression of Vitamin D Receptor on Peripheral Blood Mononuclear Cells in Patients with Psoriasis
Authors: Zanghaneh Azin Jasmin , Elmelid Andrea , Gillstedt Martin , Ahmic Omar , Andersson Bengt , Osmancevic Amra
Published: October 2024

Vitamin D plays an important role in psoriasis, but its involvement in pathogenesis remains unclear. This study aimed to evaluate vitamin D receptor (VDR) expression on peripheral blood mononuclear cells (PBMCs) in patients with psoriasis and healthy controls and to study the effects of the Etanercept treatment on VDR expression on PBMCs in patients with psoriasis. Twenty patients with moderate to severe psoriasis received treatment with Etanercept for 24 weeks. The age- and sex-matched controls did not receive any intervention. VDR expression on CD3+ lymphocytes and CD14+ monocytes, and serum levels of total and free 25-hydroxyvitamin D (25(OH)D) and 1,25-dihydroxy vitamin D (1,25(OH)2D) were analyzed at baseline, after 10–12 weeks, and after 24 weeks in both groups. VDR expression was analyzed using flow cytometry. We observed higher expression of the VDR on CD14+ monocytes in psoriasis patients compared to healthy controls at baseline. This difference was no longer significant after 24 weeks of the Etanercept treatment. The patients with psoriasis improved clinically. However, VDR expression was unaltered during the Etanercept treatment, and there was no correlation between VDR expression and disease severity.
Real-Time Bus Departure Prediction Using Neural Networks for Smart IoT Public Bus Transit
Authors: Rashvand Narges , Hosseini Sanaz Sadat , Azarbayjani Mona , Tabkhi Hamed
Published: October 2024

Bus transit plays a vital role in urban public transportation but often struggles to provide accurate and reliable departure times. This leads to delays, passenger dissatisfaction, and decreased ridership, particularly in transit-dependent areas. A major challenge lies in the discrepancy between actual and scheduled bus departure times, which disrupts timetables and impacts overall operational efficiency. To address these challenges, this paper presents a neural network-based approach for real-time bus departure time prediction tailored for smart IoT public transit applications. We leverage AI-driven models to enhance the accuracy of bus schedules by preprocessing data, engineering relevant features, and implementing a fully connected neural network that utilizes historical departure data to predict departure times at subsequent stops. In our case study analyzing bus data from Boston, we observed an average deviation of nearly 4 minutes from scheduled times. However, our model, evaluated across 151 bus routes, demonstrates a significant improvement, predicting departure time deviations with an accuracy of under 80 s. This advancement not only improves the reliability of bus transit schedules but also plays a crucial role in enabling smart bus systems and IoT applications within public transit networks. By providing more accurate real-time predictions, our approach can facilitate the integration of IoT devices, such as smart bus stops and passenger information systems, that rely on precise data for optimal performance.
Synthesis of a New Composite Material Derived from Cherry Stones and Sodium Alginate—Application to the Adsorption of Methylene Blue from Aqueous Solution: Process Parameter Optimization, Kinetic Study, Equilibrium Isotherms, and Reusability
Authors: Grigoraș Cristina-Gabriela , Simion Andrei-Ionuț
Published: October 2024

Purifying polluted water is becoming a crucial concern to meet quantity and quality demands as well as to ensure the resource’s sustainability. In this study, a new material was prepared from cherry stone powder and sodium alginate, and its capacity to remove methylene blue (MB) from water was determined. The characterization of the resulting product, performed via scanning electron microscopy (SEM) and Fourier-transform infrared spectroscopy (FTIR), revealed that the raw material considered for the synthesis was successfully embedded in the polymeric matrix. The impact of three of the main working parameters (pH 3–9, adsorbent dose 50–150 g/L, contact time 60–180 min) on the retention of MB was evaluated through response surface methodology with a Box–Behnken design. In the optimal settings, a removal efficiency of 80.46% and a maximum sorption capacity of 0.3552 mg/g were recorded. MB retention followed the pseudo-second-order kinetic and was suitably described by Freundlich, Khan, Redlich–Peterson, and Sips isotherm models. The experimental results show that the synthesized composite can be used for at least three successive cycles of MB adsorption. From these findings, it can be concluded that the use of the cherry-stone-based adsorbent is environmentally friendly, and efficacious in the removal of contaminants from the water environment.
Locomotion and Postural Control in Young Adults with Autism Spectrum Disorders: A Novel Kinesiological Assessment
Authors: Di Giminiani Riccardo , La Greca Stefano , Marinelli Stefano , Attanasio Margherita , Masedu Francesco , Mazza Monica , Valenti Marco
Published: October 2024

Background/Objectives: The purposes of the present study were to assess gait by using a novel approach that plots two adjacent joint angles and the postural control in individuals with autism (ASD) and individuals with typical neurodevelopmental (TD). Methods: The surface electromyography (sEMG) activity was measured synchronously with the other variables. Twenty young adult men, 10 with TD and 10 with a diagnosis of ASD, took part in this study. Results: There was a significant difference between ASD and TD groups in the area described by the knee–ankle diagram (p < 0.05). The sEMG activity recorded from the lateral gastrocnemius (LG) during the contact phase of gait was significantly lower in the ASD group compared with the TD group (p < 0.05). The sEMG activity recorded in the different postural conditions showed differences in LG and tibialis anterior (TA) between the ASD and TD groups (p < 0.05). Conclusions: The knee–ankle diagram provided a sensitive and specific movement descriptor to differentiate individuals with ASD from individuals with TD. The reduced LG activation is responsible for the reduced area in the knee–ankle diagram and ‘toe-walking’ in individuals with ASD and represents the common denominator of an altered ankle strategy during locomotion and postural control.
Dynamic Mechanical Performance of Glass Microsphere-Loaded Carbon Fabric–Epoxy Composites Subjected to Accelerated UV Ageing
Authors: Shaker Khubab , Asim Anas , Asghar Muhammad Ayub , Jabbar Madeha , Nasreen Adeela , Siddique Amna
Published: October 2024

This study investigates the effects of incorporating glass microspheres (GMSs) as fillers in carbon fabric–epoxy composites (CFECs) on their degradation behavior under environmental conditions such as moisture and ultraviolet rays. The GMS-filled composites were subjected to accelerated ageing and evaluated using dynamic mechanical analysis (DMA), the Charpy impact test, and inter-laminar shear strength (ILSS) tests. The results indicate that the addition of GMS fillers significantly improves the stiffness and viscoelastic behavior of the composites. However, the impact strength of the composites decreases with the addition of GMS fillers and accelerated ageing. The ILSS results demonstrate that the addition of GMS fillers improved the interfacial bonding between the carbon–epoxy matrix and fillers. This study provides insights into the mechanical properties of GMS-filled carbon–epoxy composites.
Study on the Compressive and Tensile Properties of Latex-Modified Cement Stone
Authors: Yang Lianzhi , Zhang Jie , Shen Jiyun , Ji Hongfei
Published: October 2024

The integrity of wellbores is essential for the safe and efficient operation of drilling activities. Cement plays a critical role in this process, serving as a primary barrier that isolates the casing from the surrounding formation. To ensure the proper application of cement in wells, a thorough understanding of its mechanical properties is essential. Latex-modified cement stone (LMCS) offers significant advantages due to its anti-channeling, anti-corrosion, and mechanical characteristics. This study examined the mechanical properties of LMCS through uniaxial and triaxial compression and Brazilian splitting tests. Under uniaxial compression, the elastic modulus, Poisson’s ratio, and compressive strength of LMCS were found to range from 4.08 to 8.29 GPa, 0.05 to 0.46, and 15.82 to 22.21 MPa, respectively. In triaxial compression tests with confining pressures of 2 MPa, 4 MPa, 6 MPa, 8 MPa, and 10 MPa, the elastic modulus ranged from 4.48 to 6.87 GPa, Poisson’s ratio from 0.05 to 0.16, and compressive strength from 27.38 to 39.58 MPa. The tensile strength of LMCS ranged from 2.34 to 3.72 MPa. Moreover, the compressive strength of LMCS increased with confining pressure, showing enhanced resistance to failure due to the confining effect. However, the rate of increase gradually diminished. Strength criteria for LMCS, including Mohr–Coulomb and Drucker–Prager parameters, were derived from the triaxial compression tests. These strength criteria parameters provide a useful reference for developing the constitutive model of LMCS and for simulating triaxial compression conditions. The findings of this research offer valuable insights that can guide the construction of oil and gas wells.
Modeling of Sedimentation of Particles near Corrugated Surfaces by the Meshless Method of Fundamental Solutions
Authors: Povitsky Alex
Published: October 2024

The velocity and trajectory of particles moving along the corrugated (rough) surface under the action of gravity is obtained by a modified Method of Fundamental Solutions (MFS). This physical situation is found often in biological systems and microfluidic devices. The Stokes equations with no-slip boundary conditions are solved using the Green’s function for Stokeslets. In the present study, the velocity of a moving particle under the action of the gravity force is not known and becomes a part of the MFS solution. This requires an adjustment of the matrix of the MFS linear system to include the unknown particle velocity and incorporate in the MFS the balance of hydrodynamic and gravity forces acting on the particle. The study explores the combination of the regularization of Stokeslets and placement of Stokeslets outside the flow domain to ensure the accuracy and stability of computations for particles moving in proximity to the wall. The MFS results are compared to prior published approximate analytical and experimental results to verify the effectiveness of this methodology to predict the trajectory of particles, including their deviation from the vertical trajectory, and select the optimal set of computational parameters. The developed MFS methodology is then applied to the sedimentation of a pair of two spherical particles in proximity to the corrugated wall, in which case, the analytical solution is not available. The MFS results show that particles in the pair deviate from the trajectory of a single particle: the particle located below moves farther away from vertical wall, and the particle located above shifts closer to the wall.
Amikacin Liposomal Inhalation Suspension for Non-Tuberculous Mycobacteria Lung Infection: A Greek Observational Study
Authors: Loukeri Angeliki A. , Papathanassiou Evgenia , Kavvada Aikaterini , Kampolis Christos F. , Pantazopoulos Ioannis , Moschos Charalambos , Papavasileiou Apostolos
Published: October 2024

Background and Objectives: Intravenous amikacin, recommended for severe or recurrent M. avium complex (MAC) infections and as initial treatment for M. abscessus lung disease, is often limited by serious adverse effects such as renal and auditory toxicities. Inhaled Amikacin Liposome Inhalation Suspension (ALIS) enhances pulmonary drug deposition while minimizing systemic adverse effects, and it has recently been introduced as an add-on therapy for refractory MAC infections or when other standard treatments are inadequate. This study aims to retrospectively describe the outcomes of Greek patients with difficult-to-treat non-tuberculous mycobacterial (NTM) lung disease following the addition of ALIS to guideline-based therapy. Materials and Methods: Seventeen consecutive patients (median age: 66 years) treated with ALIS as an add-on therapy to a standard regimen at “Sotiria” General Hospital of Chest Diseases (Athens, Greece) from 2020 to 2023 were enrolled in this study. These patients had recurrent or refractory NTM lung disease and/or limited treatment options due to prior treatment-related adverse effects. Clinical, radiological, and microbiological data on treatment response and overall outcomes after ALIS initiation were recorded for each patient. Results: By the end of 2023, 14 out of 17 patients had either successfully completed or were continuing their ALIS therapy. At 6 months, 85.7% (12/14) showed clinical, microbiological, and radiological improvement. However, 25% (3/12) of treated patients, primarily those with monomicrobial or combined M. abscessus lung disease, experienced disease relapse after therapy completion. The most frequent adverse effects related to ALIS were mild and localized to the respiratory tract, with only one patient discontinuing therapy due to hypersensitivity pneumonitis. Conclusions: Adding ALIS to standard regimens was effective and safe in a small group of Greek patients with refractory or recurrent NTM lung disease, particularly those who had discontinued intravenous aminoglycosides due to significant adverse effects, with notable responses observed in MAC lung disease. Further research is needed to validate these findings in clinical practice and to investigate ALIS’s role in NTM lung disease caused by other species.
Synthesis of an Ethylenediaminetetraacetic Acid-like Ligand Based on Sucrose Scaffold and Complexation and Proton Relaxivity Studies of Its Gadolinium(III) Complex in Solution
Authors: Zhang Ping , Barbot Cécile , Gandikota Ramakrishna , Li Cenxiao , Gouriou Laura , Gouhier Géraldine , Ling Chang-Chun
Published: October 2024

Sucrose constitutes a non-toxic, biodegradable, low-cost and readily available natural product. To expand its utility, we developed total synthesis for a ligand based on a sucrose scaffold for potential use as a metal chelation agent. The designed target (compound 2) has a metal-chelating functionality at both the C-6 and C-6’ positions, which can provide a first coordination sphere of eight valencies. The designed total synthesis was highly efficient. To demonstrate the utility of the ligand, we studied its complexation with Gd(III). Using potentiometric titration and high-resolution mass spectrometry, we confirmed the formation of a 1:1 complex with Gd(III), which has a respectable formation constant of ~1013.4. Further NMR relaxivity studies show that the Gd(III) complex has a relaxivity (r1) of 7.6958 mmol−1 s−1.
Liposome-Assisted Drug Delivery in the Treatment of Multiple Sclerosis
Authors: Greco Giuliana , Sarpietro Maria Grazia
Published: October 2024

Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the nervous system that leads to neurological dysfunctions and severe disabilities. It is worth noting that conventional pharmacotherapy is poorly selective and causes toxicity problems and several systemic side effects. Thus, there is a need to develop new approaches to this medical challenge. The use of nanocarriers for drug delivery represents a good strategy to overcome several issues such as high therapeutic drug doses with side effects, such as diarrhea, nausea, and abdominal pain, and drug degradation processes; in addition, nanocarriers can provide controlled and targeted drug release. This review describes the application of liposomes for the delivery of pharmaceutical actives to target MS. Firstly, MS is explained. Then, liposomes are described along with their preparation, characterization, and stability. The literature about the use of liposomes for the treatment of MS is then analyzed.
Click to Correction: Interactive Bidirectional Dynamic Propagation Video Object Segmentation Network
Authors: Yang Shuting , Yuan Xia , Luo Sihan
Published: October 2024

High-quality video object segmentation is a challenging visual computing task. Interactive segmentation can improve segmentation results. This paper proposes a multi-round interactive dynamic propagation instance-level video object segmentation network based on click interaction. The network consists of two parts: a user interaction segmentation module and a bidirectional dynamic propagation module. A prior segmentation network was designed in the user interaction segmentation module to better segment objects of different scales that users click on. The dynamic propagation network achieves high-precision video object segmentation through the bidirectional propagation and fusion of segmentation masks obtained from multiple rounds of interaction. Experiments on interactive segmentation datasets and video object segmentation datasets show that our method achieves state-of-the-art segmentation results with fewer click interactions.
WiFi-Based Human Identification with Machine Learning: A Comprehensive Survey
Authors: Mosharaf Manal , Kwak Jae B. , Choi Wooyeol
Published: October 2024

In the modern world of human–computer interaction, notable advancements in human identification have been achieved across fields like healthcare, academia, security, etc. Despite these advancements, challenges remain, particularly in scenarios with poor lighting, occlusion, or non-line-of-sight. To overcome these limitations, the utilization of radio frequency (RF) wireless signals, particularly wireless fidelity (WiFi), has been considered an innovative solution in recent research studies. By analyzing WiFi signal fluctuations caused by human presence, researchers have developed machine learning (ML) models that significantly improve identification accuracy. This paper conducts a comprehensive survey of recent advances and practical implementations of WiFi-based human identification. Furthermore, it covers the ML models used for human identification, system overviews, and detailed WiFi-based human identification methods. It also includes system evaluation, discussion, and future trends related to human identification. Finally, we conclude by examining the limitations of the research and discussing how researchers can shift their attention toward shaping the future trajectory of human identification through wireless signals.
When to Measure Accessibility? Temporal Segmentation and Aggregation in Location-Based Public Transit Accessibility
Authors: Lindner Anna , Kühnel Fabian , Schrömbges Michael , Kuhnimhof Tobias
Published: October 2024

Accessibility analyses are important for public transit (PT) planning, as they reveal possible deficits in PT services. Since such accessibility analyses are highly time-dependent, the Modifiable Temporal Unit Problem (MTUP) should be considered. In this context, one approach is to calculate accessibility continuously for an entire day and aggregate it appropriately. However, this approach is complex and computationally intensive and is therefore rarely, if ever, applied. Instead, practitioners and researchers rely on simplified methods without considering temporal effects in detail. This paper bridges this gap by developing a simple yet representative method to account for the temporal variability of PT services. For this purpose, we calculate and compare PT accessibility for different time windows and through different aggregation methods for Germany. The results show that PT analyses between 9–11 a.m. were most representative. Alternatively, the time windows between 7–9 a.m. and between 1–3 p.m. adequately reflected accessibility. The median was suitable for aggregating individual time intervals into a representative value for the PT service throughout a day, while the maximum or mean value distorted the results. For practical planning purposes, we therefore recommend using the 9–11 a.m. time window.
VR-technologies in medical education
Authors:   Innovative Academy of Professional Development «Docstarclub», Demkina A.E. , Korobeynikova A.N. ,   Center of Cardiology and Neurology
Published: October 2024

The introduction of IT technologies is one of the important aspects of the successful development of the healthcare industry. Digitalization will affect various fields of medicine: from scientific research and development of new equipment to the system of training professional personnel and ways of interacting with patients. The need to practice the skills of a doctor, on the one hand, and the deontological and ethical aspects of training on real patients, on the other hand, gave impetus to the introduction of VR technologies (virtual reality technologies) into medical education. The prospects for a variety of plot content of programs, the development of practical competencies to automatism, reducing the burden on a teacher or mentor — all these advantages of VR technologies make them convenient to use and enable a specialist for continuous development. However, on the other hand, there are factors that signifi cantly limit the implementation of this innovative tool: the need for additional technical support, the need for teaching staff training and the lack of high-quality software content. The emergence of relevant experience in using technology in practice, the development of new software products, and the expansion of virtual reality applications — all this will allow for a more in-depth and versatile assessment of the possibilities of using VR technologies in medical pedagogy.
GLOBALTRADE AND ECONOMIC TRANSFORMATIONS - PREREQUISITES FOR THE REENGINEERING OF TRANSNATIONAL LOGISTICS COMMUNICATIONS IN RUSSIA (USING THE EXAMPLE OF THE EASTERN POLYGON)
Authors:   The State Duma, Eremin Sergei Vasilievich
Published: October 2024

The article deals with topical issues of the modern national and transnational system of movement of goods and cargoes. Using the example of transportation of general raw materials along the Siberia - Far East latitudinal route, options for creating alternative cargo distribution hubs with a system of meridian corridors are proposed. Attempts have been made to integrate the tasks of stra-tegic development of the country's transport complex until 2030 with the tasks of economic diversification of the domestic economy and redistribution of commodity logistics.
ROBOTIC-TECHNICAL METHOD FOR CONTROL OF EMERGENCY OPERATING MODES OF FIRE ENGINES
Authors:   St. Petersburg University of the State Fire Service of the Ministry of Emergency Situations of Russia, Lozhkin Vladimir Nikolaevich , Satsuk Ivan Vladimirovich ,   St. Petersburg University of the State Fire Service of the Ministry of Emergency Situations of Russia
Published: October 2024

In the aspect of the development of motor transport intelligent systems, a method for diagnosing environmental, fire and hazardous operating conditions of piston engines with compression ignition (diesels) is proposed. The method is based on the use of a robotic manipulator, which sets the free acceleration mode of the required standard intensity using the processor device according to the original program. The method identifies dangerous modes of technical operation using analysis of the exhaust gas composition and was tested on a model full-size diesel engine 4Ch11/12.5 in bench conditions.
HUBUNGAN PERSEPSI SISWA TENTANG MANAJEMEN KURIKULUM DAN KECERDASAN SPIRITUAL SISWA DENGAN HASIL BELAJAR SISWA PADA MATA PELAJARAN AQIDAH AKHLAK
Authors: Khasanah Khasanah , Ispurwanti Ispurwanti
Published: October 2024

This study aims to determine the positive relationship between students' perceptions of curriculum management on Aqidah Akhlak Learning Outcomes. To find out the positive relationship between students' spiritual intelligence on Aqidah Akhlak Learning Outcomes. To find out the positive relationship between students' perceptions of curriculum management and students' spiritual intelligence together with the Aqidah Akhlak Learning Outcomes at Madrasah Aliyah Bekasi Regency. This type of research is a descriptive correlation research. The population is by taking class XI students from three Madrasah Aliyah, namely 30 students of Class X1 Mas Nur Al Ghozy, 30 students of Class X1 Mas Al Ajhariyah, 30 students of Class X1 Mas Plus Roudhotul Muhibbin Bekasi, the sample in this study was 90 people. The analysis technique used is a quantitative analysis technique using the statistical program SPSS (Statistical Product and Service Solutions) version 20 by processing linearity test data, homogeneity test. and statistical hypothesis. The results of the study show that there is a positive relationship between curriculum management and the learning outcomes of Aqeedah Akhlak students of class XI Madrasah Aliyah, Bekasi Regency. There is a positive relationship between spiritual intelligence and the learning outcomes of Aqidah Akhlak students of class XI Madrasah Aliyah, Bekasi Regency. There is a positive relationship between curriculum management and spiritual intelligence with the learning outcomes of Aqeedah Akhlak students of class XI Madrasah Aliyah, Bekasi Regency..
Estudio de las características léxicas y morfosintácticas de un corpus de maternés en español de la ciudad de Córdoba (Argentina)
Authors: Paolantonio María Patricia , Di Gregorio Gabriela , Menti Alejandra Beatriz , Manoiloff Laura María Victoria
Published: October 2024

El objetivo de esta investigación ha sido construir un corpus de maternés en español rioplatense dirigido a bebés entre 3-6 meses de edad, a partir de sesiones de interacción semiestructurada en laboratorio y analizar las características léxicas y morfosintácticas de esta particular modalidad discursiva. Se observó que, en el lenguaje dirigido a bebés de 3 meses, la cantidad de morfemas por palabra, la ratio de palabras distintas y la diversidad léxica son significativamente menores en comparación con otras edades. La duración media del enunciado materno aumentó hacia los 4 meses de edad infantil y disminuyó hacia los 5 y 6 meses de edad infantil, con una media entre 2.3 (3 meses) y 3.5 (4-6 meses) de morfemas por emisión. Respecto a las repeticiones, se observó un aumento progresivo hasta alcanzar su pico máximo a los 5 meses de edad infantil y una leve disminución a los 6 meses. Este estudio permitió ampliar el conocimiento sobre las características del input lingüístico que reciben los bebés en los primeros momentos de la etapa prelingüística en una variante del español poco estudiada hasta el momento.
A prevalência de Policitemia Secundária em portadores de Doença Pulmonar Obstrutiva Crônica (DPOC) e suas implicações na Capacidade de Difusão do Monóxido de Carbono (DLCO): revisão de literatura
Authors: Melo Maria Beatriz Meneses , Nogueira Danilo Brito , Melo Saulo Maia d’Avila
Published: October 2024

A Doença Pulmonar Obstrutiva Crônica (DPOC) é uma das principais causas de morbidade e mortalidade no mundo e representa um enorme desafio da saúde pública. A policitemia secundária é reconhecida como uma complicação importante da DPOC que é pouco estudada, tornando-se um admirável objetivo de pesquisa. Nossa revisão narrativa da literatura teve como objetivos demonstrar a prevalência de policitemia secundária na DPOC, determinar os mecanismos pelos quais a DPOC produz policitemia e como a Capacidade de Difusão do Monóxido de Carbono (DLCO) sofre alterações na policitemia secundária, e se a correção da hemoglobina é utilizada na DLCO. Concluímos que a prevalência de policitemia secundária na DPOC, mesmo com a evolução do tratamento desta patologia, ainda é tema importante e significativo na prática clínica, e sua prevalência oscila de 2 a 10%, sofrendo influência da gravidade da doença, utilização de oxigenoterapia domiciliar, hábito tabágico, coexistência de comorbidades, residir em regiões de alta altitude e da redução da DLCO. Diversos mecanismos estão envolvidos na policitemia secundária causada pela DPOC e suas implicações na DLCO. Apesar da policitemia secundária alterar os resultados da DLCO pelos níveis altos de hemoglobina, existem falhas na utilização da correção da hemoglobina na DLCO, resultando em um valor da DLCO artificialmente alterado que pode influenciar significativamente na interpretação clínica da DLCO.
A utilização da drenagem linfatica no pós-cirúrgico de lipoaspiração em abdome
Authors: Borges Vanessa , Braga Cristina , Cavalcante Fabrício Vieira , Ocon Carlos Alberto , Cunha Márcio Fernandes da , Lazzareschi Leandro , Aragão Neylor Rodrigo Oliveira , Santos Gleyce Kelly de Brito Brasileiro , Fernandes Antônio de Olival , Vieira Marina Provinciali Mendonça , Almeida Jacqueline Cunha Cabral Azevedo , Ribeiro Filho Alfredo , Filoni Eduardo
Published: October 2024

Atualmente a busca pelo corpo perfeito e a forma estética ideal vem aumentando significativamente a procura por procedimentos cirúrgicos estéticos e reparativos com o intuito de um corpo harmoniosa e saudável. E assim recorrem a inúmeros tratamentos estéticos e cirúrgicos, dentre estes a lipoaspiração, que corresponde atualmente a uma técnica simples, rápida, pouco dispendiosa e, quando bem indicada, apresenta excelentes resultados. No entanto, esta técnica, mesmo sendo segura, pode apresentar algumas complicações pós cirúrgico, como aderências teciduais, fibroses, equimoses e edemas, e consequentemente, dor, o que incomoda bastante os pacientes. Desta forma, a qualidade do resultado de uma cirurgia plástica não depende apenas do seu planejamento operatório, mas também da intervenção e cuidados pós e pré cirúrgicos. No intuito de tratar tais complicações e potencializar a intervenção de lipoplastia, médicos cirurgiões, enfermeiros, esteticistas e fisioterapeutas utilizam se da técnica de drenagem linfática manual (DLM) como um dos procedimentos primordiais para a obtenção de melhores resultados. Este estudo tem o objetivo de descrever a resposta fisiológica dos principais recursos utilizados na prática clínica do profissional fisioterapeuta, bem como analisar os efeitos da DLM (Drenagem Linfática Manual) no tratamento pós-operatório imediato de lipoaspiração de abdômen. Para o desenvolvimento deste foram revisados artigos precedentes das bases de dados eletrônicas LILACS, MEDLINE/Pubmed, Biblioteca Cochrane, Scielo, com o tema proposto a importância da drenagem linfática no pós-cirúrgico de lipoaspiração de abdome. Mediante a esta afirmativa, esta pesquisa se propôs através de revisão bibliográfica integrativa descrever quais os benefícios da drenagem linfática manual no pós-operatório de lipoplastia abdominal, espera se que este estudo possa contribuir de maneira positiva para ampliação do conhecimento dos profissionais que atuam ou pretendem atuar na área dermato-funcional.
O que se sabe sobre a influência da luz azul na saúde ocular? Uma revisão integrativa
Authors: Zaki Isabela Bicalho , Sobral Marcelo Luiz Peixoto , Nunes Thomaz Silva , Yokoya Márcio , Conceição Júlia Horta Vianna Souza da
Published: October 2024

Introdução: A era da informática trouxe benefícios significativos, para a humanidade, incluindo acesso à internet e home-office. No entanto, trouxe problemas relacionados ao uso excessivo de produtos tecnológicos. Apresenta estatísticas sobre o tempo que os brasileiros passam conectados à internet e destaca os efeitos da luz azul nos tecidos celulares, incluindo o risco de comprometer o funcionamento celular e problemas relacionados à saúde ocular, como a degeneração macular relacionada à idade, miopia, síndrome do olho seco e lentidão para focar. Objetivo: Analisar o efeito da luz azul na saúde ocular. Metodologia: Este estudo caracteriza-se como uma revisão bibliográfica do tipo integrativa, tendo como base, produções científicas de 2018-2023, dando preferência àqueles publicados nas seguintes bases de dados: National Library of Medicine (PubMed), Scientific Eletronic Library On-line (SciELO) e US National Library of Medicine (NCBI). Resultados: O resultado apresentado em relação ao estudo feito demonstra as principais complicações oculares, sendo elas: degeneração macular relacionada à idade (DMRI), miopia, catarata, síndrome do olho seco, hiperemia, irritação/ardor compatível com a Síndrome da Visão de Computador (SVC), lentidão para focar, entre outras. Graças a isso, é possível informar e também alertar a sociedade para que tenham uma melhor compreensão sobre os danos de curto, médio e longo prazo do uso excessivo de aparelhos eletrônicos por um longo período do dia, no olho humano. Conclusão: A luz azul traz ao olho as seguintes complicações: degeneração macular relacionada à idade (DMRI), miopia, catarata, síndrome do olho seco, hiperemia, irritação/ardor compatível com a Síndrome da Visão de Computador (SVC) e lentidão para focar entre outras. O aumento da ingesta ou suplementação dos carotenóides tem efeito benéfico considerável na progressão das doenças oculares. É necessário que pesquisas futuras sejam realizadas, com o intuito de expandir as descobertas sobre novas influências e patologias ocasionadas pelo uso indiscriminado da luz azul na saúde ocular.
Incorporação do óleo essencial de capim-limão na produção de queijo petit suisse
Authors: Rocha Maurílio Vieira da , Cardoso Polyana de Faria , Rosa Fernanda Coutinho Pinheiro da , Boas Brígida Monteiro Vilas , Aparecido Lucas Eduardo de Oliveira , Silva Délcio Bueno da
Published: October 2024

Produtos funcionais têm ganhado destaque no mercado devido à crescente demanda por uma alimentação saudável. Este estudo teve como objetivo avaliar a adição do óleo essencial de capim-limão, que contém a substância bioativa citral, nas características físico-químicas, microbiológicas e reológicas do queijo Petit Suisse. Foram produzidas seis formulações de queijo Petit Suisse, cada uma em quatro repetições, com concentrações variáveis de óleo essencial: T1 (ausência de óleo essencial), T2 (27 mg/L), T3 (53 mg/L), T4 (108 mg/L), T5 (161 mg/L) e T6 (215 mg/L). Os parâmetros avaliados aos 1, 15, 30 e 45 dias após a fabricação incluíram pH, teor de umidade, teor de proteina, teor de gordura, viscosidade, contagem de coliformes totais e termotolerantes, contagem de S. aureus coagulase positiva, contagem de bactérias láticas e contagem de leveduras e fungos filamentosos. A confirmação do teor da substância bioativa citral no óleo essencial foi realizada por meio de cromatografia gasosa. O delineamento estatístico utilizado foi inteiramente casualizado em esquema fatorial (6 x 4). Apenas o pH médio aos 45 dias apresentou diferença significativa em comparação às demais amostras, sendo menor em todos os tratamentos. Os outros parâmetros não mostraram interferência significativa devido à adição do óleo essencial. Conclui-se que o óleo essencial de capim-limão pode ser utilizado como fonte de citral na produção de queijo Petit Suisse, sem alterar os padrões de identidade e qualidade estabelecidos pela legislação vigente.
Prevalência de alterações torácicas em doenças obstrutivas crônicas - uma revisão bibliográfica
Authors: Silva Danielle Cristine da , Zupirolli Beatriz Beraldo , Pavanello Audrei , Rampinelli Amanda Paixão , Brocco Ana Lara , Arnold Beatriz , Malagutti Dayader Batista , Sermidi Maíra Peres , Vasconcellos Pedro Henrique Diniz Venancio
Published: October 2024

Introdução: De acordo com evidências atuais as doenças respiratórias tem alta relevância em todas as faixas etárias brasileiras, assim como é notável os sinais e sintomas presentes em pacientes com alterações torácicas. Dessa forma, o atual estudo investiga a relação do desenvolvimento da asma e DPOC pós alterações torácicas ou o contrário disso, se tais alterações nas vias aéreas impactam a anatomia torácica dos pacientes afetados. Objetivos: O objetivo deste estudo foi analisar como as alterações pulmonares e torácicas influenciam a qualidade de vidas dos pacientes e como elas estão sendo apresentadas na prática clínica, trazendo ou não benefícios aos doentes. Metodologia: O estudo trata-se de uma revisão bibliográfica de literatura, foi realizado a coleta em diversas bases de dados de nacionalidades distintas. Conclusão: Foi identificado que não existe uma relação clara entre o pectus excavatum e o desenvolvimento da asma brônquica, o que a literatura atual nos trás é que a mudança da caixa torácica desenvolve asma induzida por exercícios em pacientes com tal deformação. Já a DPOC trás alterações torácicas significativas aos pacientes acometidos, principalmente em âmbito de musculatura torácica e músculos auxiliares da respiração, expandindo a caixa torácica desses pacientes.
Anastomose coloanal primária com reservatório colônico e ileostomia protetora versus anastomose coloanal com maturação tardia à Simonsen: comparação, resultados perioperatórios e da qualidade de vida
Authors: Silveira Thiago Rezende , Mesquita Rafael Marques de , Silva Emerson Abdulmassih Wood da , Ferraz Pedro Brum da Silveira , Pelegrinelli Luciano Ricardo , Souza Gabriela Corrêa de , Oliveira Gustavo Aguiar de
Published: October 2024

Os avanços técnicos na cirurgia colorretal e a melhoria dos princípios oncológicos, como a diminuição das margens cirúrgicas, permitiram a melhora da performance das anastomoses coloanais e reduziram a incidência de colostomias definitivas, tornando o tratamento possível sem comprometer os objetivos oncológicos. Desse modo o presente estudo tem como objetivo avaliar dois métodos cirúrgicos, a anastomose coloanal primária com a confecção de ileostomia protetora versus a anastomose coloanal com maturação tardia à Simonsen. Para tanto, realizamos uma análise retrospectiva de dados de prontuários de pacientes em um hospital-escola do interior de Minas Gerais, submetidos aos respectivos procedimentos cirúrgicos. Posteriormente, aplicamos o Score Lars nos pacientes selecionados para obtermos dados sobre a morbidade dor procedimento e a qualidade de vida após o tratamento. Como resultado, pudemos observar grande morbidade em ambos os grupos, sendo que complicações mais severas, como a deiscência de coto foi significativamente menos prevalente no segundo grupo e apresentou melhor prognóstico, no entanto, dentro do quadro geral, concluímos que a escassez de alguns dados dificultaram a análise, sendo necessário ampliar o estudo para melhorar sua acurácia e delinear melhor os riscos e benefícios de cada procedimento.
Vasculite leucocitoclástica cutânea com acometimento sistêmico: relato de caso e revisão de literatura
Authors: Teixeira Kamyla Mascena , Sena Savio Ricardo Bezerra , Rodrigues Neimar
Published: October 2024

A Vasculite Leucocitoclástica, conhecida também como vasculite de hipersensibilidade, é uma doença que acomete vasos de pequeno calibre, sobretudo vênulas. A fisiopatologia está associada à deposição de imunocomplexos e, sob análise histopatológica, apresenta as seguintes características: fragmentação de núcleos de neutrófilos, edema de células endoteliais, extravasamento de hemácias e necrose fibrinoide. O acometimento é comumente restrito a região cutânea, entretanto, em torno de 50% dos portadores da doença também apresentam acometimento sistêmico. No geral, o paciente apresenta lesões dermatológicas com evolução progressiva e um quadro clínico complexo e inespecífico, tornando a investigação difícil. O diagnóstico é confirmado pelo exame histopatológico e o tratamento basea-se no uso de corticosteroides. O tipo de estudo é um relato de caso. Ao observar inúmeras publicações na literatura, é consensual a elevada complexidade da investigação etiológica, ocasionando demora excessiva, elevado custo, retardo no início do tratamento e, consequentemente, pior prognóstico para o paciente, motivo pelo qual é imprescindível conhecer tal patologia. O objetivo é relatar o caso de Vasculite Leucocitoclástica Cutânea com acometimento sistêmico e realizar um levantamento bibliográfico, através de uma descrição de um relato de caso de uma paciente do sexo feminino, do interior de Minas Gerais, internada por quadro de lesões dermatológicas. Pesquisa bibliográfica da literatura nacional e internacional, abrangendo relatos de caso, estudo de casos, artigos de revisão, artigos originais e metanálises. Os resultados serão analisados em forma de discussão entre o relato de caso e revisão realizada na literatura
طبيعة وأسباب التهكم التنظيمي بين الموظفين العراقيين: دراسة تجريبية حقلية باستخدام السيناريوهات
Authors: العطوي عامر علي
Published: October 2024

تهدف هذه الدراسة إلى استكشاف طبيعة ظاهرة التهكم التنظيمي لدى الموظف العراقي والتعرف إلى أهم العوامل التي تسبب إيقادها من خلال اعتماد المدخل التجريبي المستند على السيناريوهات. وعلى نحوٍ محدد فإن التحقيق التجريبي والمفاهيمي لهذه الدراسة يتساءل إن كانت حالة التهكم التنظيمي لدى الموظف العراقي نابعة من إدراك موقف أو ظاهرة تنظيمية معينة، أو ناشئة عن موقف متزمت تجاه المنظمات والإدارات العليا التي تقودها، أو أنها مزية لديه تجاه الطبيعة الإنسانية بشكل عام. كما تسلط الدراسة الضوء على اختبار دور بعض المتغيرات التي تؤثر في التهكم التنظيمي: وهي التسييس التنظيمي، وفشل مساعي التغيير التنظيمي السابقة، والنفاق التنظيمي. وقد صممت الدراسة سيناريوهات مختلفة تحاكي وجود هذه الظواهر في المنظمات الحكومية العراقية. وقد وزعت هذه السيناريوهات على عينة من دوائر حكومية مختلفة في محافظة القادسية. واستخدمت الدراسة مجموعة من الأدوات الإحصائية المناسبة تضمنت على سبيل المثال تحليل (MANOVA) وتحليل (ANOVA). وقد أظهرت النتائج صحة معظم فرضيات الدراسة، وفي ضوئها صيغت مجموعة من التوصيات الهادفة.