bluuebunny/crossref_metadata_2025 huggingface dataset:
PBX1 Participated in Estrogen Mediated Bladder Cancer Progression and Chemo-Resistance through Affecting Estrogen Receptors
Authors: Zhao Yang , Che Jizhong , Tian Aimin , Zhang Gang , Xu Yankai , Li Shuhang , Liu Songlin , Wan Yinxu
Published: August 2021

Bladder cancer (BCa) is a common cancer associated with high morbidity and mortality worldwide. Pre-B-cell leukemia transcription factor 1 (PBX1) has been reported to be involved in tumor progression. The aim of the study was to explore the specific role of PBX1 in BCa and its underlying mechanisms. The relative expressions of PBX1 in muscle-invasive BCa tissues and cell lines were analyzed through RT-qPCR and Western blotting. Kaplan–Meier analysis was used to analyze the relationship between PBX1 levels and survival status. Co-immunoprecipitation (CO-IP) and chromatin immunoprecipitation (ChIP)-qPCR assay were adopted to verify the interaction between PBX1 and Estrogen receptors (ERs), and explore the ER-dependent genes transcription. The results shown that PBX1 was upregulated in invasive BCa patients and BCa cells, positively associated with tumor size, lymph node metastasis, distant metastasis and poorer survival status. Overexpression of PBX1 promoted cell growth, invasion, epithelial-mesenchymal transition (EMT) process and cisplatin resistance in BCa cells, while the silence of PBX1 showed opposite effects. Further, PBX1 interacted with Estrogen receptors (ERs) and was required for the ER function. Overexpression of PBX1 aggravated the tumor-promoting effect of estrogen on BCa cells, while partially suppressed the inhibitory effects of ER antagonist AZD9496 on BCa cells. In summary, this study revealed that PBX1 participated in estrogen mediated BCa progression and chemo-resistance through binding and activating estrogen receptors. Hence, PBX1 may serve as a potential prognostic and therapeutic target for BCa treatment.
Response Surface Methodology for Optimization of Rotating Biological Contactor Combined With An External Membrane Filtration
Authors: Waqas Sharjeel , Harun Noorfidza Yub , Bilad Muhammad Roil , Samsuri Taufik , Nordin Nik Abdul Hadi
Published: August 2021

A large amount of wastewater is directly discharged into water bodies without treatment causing surface water contamination. Conventional treatment techniques produce lower effluent quality and are energy extensive. Rotating biological contactor (RBC) is an attractive biological wastewater treatment that offers a low energy footprint. However, its unstable removal efficiency makes it less popular. This study optimizes operating parameters in RBC combined with external membrane filtration (RBC-ME) in which the latter acts as a post-treatment step to stabilize the biological performance. Response Surface Methodology (RSM) was employed to optimize the biological and filtration performance by exploiting three parameters of disk rotational speed, hydraulic retention time (HRT), and sludge retention time (SRT). Results show that RBC-ME exhibits excellent biological treatment capacity and higher effluent quality. It attained 87.9 ± 3.2% of chemical oxygen demand, 45.2 ± 0.7% total nitrogen, 97.9 ± 0.1% turbidity, and 98.9 ± 1.1% ammonium removals. The RSM data demonstrated that the experimental data and model predictions agreed well. Under the most optimum parameters, the permeability of 144.6 L/m2 h bar could be achieved at 36.1 rpm disk rotational speed, 18 h HRT, and 14.9 d SRT. This work demonstrates the effective use of statistical modeling to enhance RBC-ME system performance to obtain a sustainable and energy-efficient treatment process to prevent human health and the environment.
Altered Intestinal Microbiomes and Lipid Metabolism in Patients With Chronic Disorders of Consciousness
Authors: Luo Benyan , Yu Jie , Cheng Qisheng , He Fangping , Meng Fanxia , Yu Yamei , Xu Chuan , Wen Xinrui , Hong Lirong , Gao Jian , Li Jingqi , Pan Gang , Li Ming D.
Published: August 2021

Intestinal microbiotas regulate brain function of the host through the production of a myriad of metabolites and are associated with various neurological diseases. Understanding intestinal microbiome of patients in chronic disorders of consciousness (DoC) is important for the evaluation and treatment of the disease. To investigate the difference of intestinal microbiome and short-chain fatty acids (SCFAs) among the patients in vegetative state (VS), minimally conscious state (MCS) and emerged from minimally conscious state (EMCS), as well as the influence of antibiotics on these patients, 16S rRNA sequencing and targeted lipidomics were performed on their fecal samples and EEG signals analysis were used to evaluate their brain function. Our results showed that intestinal microbiome among the three groups differed greatly and some microbial community with its production of SCFAs were reduced in VS patients compared to the other two groups. Moreover, reduced microbial communities and five major SCFAs along with attenuated brain functional connectivity were observed in MCS patients treated with antibiotics compared to those received no antibiotic treatment, but not in the other pairwise comparisons. Finally, three genera level of microbiota, Faecailbacterium, Enterococcus and Methanobrevibacter, were considered as potential biomarkers to distinguish patients in MCS from VS with high accuracy both in the discovery cohorts and validation cohorts. Together, our findings improved the understanding of patients with chronic DoC from intestinal microbiome and provided a new reference for therapeutic targets exploration.
Adsorption Behavior of Cationic Dye on Bentonite Functionalized With 3-aminopropyltriethoxysilane
Authors: BELHADRI MAZOURI , Mokhtar Adel , Bengueddach Abdelkader Bengueddach , sassi mohamed
Published: August 2021

The current study focused on the modification of Algerian bentonite clay (Bent) with the product of hydrolysis of 3-aminopropyltriethoxysilane (APTES) using the intercalation process. The modified clay (Bent-APTES) was investigated as an adsorbent solid for methylene blue dye (MB) removal from wastewater.The Bent-APTES was characterized by X-ray diffraction (XRD), chemical analyses, Fourier-transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). The cationic exchange capacity was also determined. Several adsorption parameters were evaluated on the adsorption performance. The results showed that the equilibrium adsorption data was found to fit better to the Langmuir adsorption model, and the adsorption capacity for the removal of MB on Bent-APTES was 217.39 mg g-1. The kinetic process of adsorption could be described by the pseudo-second order model. Consequently, the modified clay could be served as an efficient adsorbent for cationic dyes in wastewater treatment.
Effect of Pulsed Electric Fields on Enhanced Extraction and Cytotoxicity of Poly-Herbal Mixtures Against Estrogen Receptor-Positive Breast Cancer Cell Lines
Authors: Sadasivam Poompavai , Varadara Gowri Sree
Published: August 2021

The mixture of different bioactive constituents from plant extracts and several other natural products produces synergistic effects. This synergistic activity aids in treating and preventing various diseases by reducing the usage of conventional drugs. The present investigation aimed to study the effect of poly-herbal formulations of selected plants (Turmeric, Pepper, Neem, Vinca rosea ) on improved biological activity with and without pulsed electric fields(PEF). Selected plant extracts were combined in different proportions(1% to 3%) to formulate a poly-herbal mixture. Ethanolic crude extracts were extracted by Soxhlet method and their phenolic activity and antioxidant activity were quantified. Further, to enhance the recovery of intracellular components, electrical fields of different parameters were used. The effect of PEF on formulated mixtures was compared with untreated extracts, which exhibited higher phenolic and antioxidant activity than untreated extracts. Out of all combinations, turmeric with pepper showed higher phenolic and antioxidant activity, and hence, these combinations were checked for their potential cytotoxicity against MCF-7 Estrogen breast cancer cells. In addition, different electrical ((EP1)High intensity,short duration & (EP2)Low intensity,long duration) pulses were used to enhance the uptake of extracts into the cell membrane. Lowest cell viabilities of 19.41%(raw extract),14.75%(pulsed extract),13.28%(pulsed extract+EP1) and 9.982%(Pulsed extract+EP2) after 72hrs of treatment for 1000μg/ml concentration of turmeric(97%) and pepper(3%) mixture was observed. This shows the potential of the synergistic effect of electrical pulses and poly-herbal mixture, achieving phenolic and antioxidant-rich extracts causing higher cell death. This technique can be used as an effective method to treat breast cancer avoiding undesirable side effects due to higher doses of synthetic drugs and single herb.
Clinical Study on the Intervention of Coptis Root and Ginseng on gut microbiota in Type 2 Diabetes: a study protocol for a randomized controlled and double-blinding trial
Authors: Jiang Li , Fu Qiang , Huang Weijun , Chen Yu , Li Jiayue , Xiao Yonghua , Shen Esther Aijia , Wang Junheng , Li Zhuang , Liu Jiangteng , Fu Xiaozhe , Liu Yuanyuan , Zhao Yu , Su Guanxun , Wang Shidong , Zhao Jinxi
Published: August 2021

Background: Type 2 Diabetes Mellitus (T2DM) is a complex metabolic disease caused by complicated factors, the pathogenesis of which has not been determined. Traditional Chinese medicine(TCM) could effectively regulate blood sugar and influence gut microbiota in T2DM patients. Preliminary studies showed that the coptis root and ginseng (RG) formula could relieve insulin resistance and regulate the progression of diabetes in mice. The purpose of this study is to explore the efficacy and safety of RG formula in the treatment of adult patients with T2DM, as well as observing its effects on gut microbiota.Methods and analysis: This trial is a randomized, double-blind, placebo-controlled study. A total of 60 participants will be randomized in a 1:1 ratio into an experiment group (RG formula) and a control group (placebo). Patients in both groups will be given diabetes education and basic blood glucose control. Glucose-lowering drugs with significant influence on gut microbiota will be avoided. This trial will last 25 weeks including 1 week run-in, 12 weeks intervention and 12 weeks follow-up visit. The primary outcome is the change in the HbA1c. The secondary outcomes comprise the change in the fasting blood glucose(FBG), postprandial blood glucose(PBG) fasting insulin(FIL), fasting C-peptide(C-P), insulin resistance index(IRI), inflammatory factors and species abundance of gut microbiota between the two groups. Safety in medication will also be evaluated. The correlation analysis will be explored between the glycemic indicators,inflammatory factors and abundance of gut microbiota.Discussion: This study will provide the clinical evidence for the efficacy of RG formula in regulating blood sugar and influencing gut microbiota, which will be beneficial to form the integrated therapeutic regimen in T2DM with TCM.Trial registration: “Clinical Study on the Intervention of Coptis Root and Ginseng”, Chinese Clinical Trials Registry ChiCTR 2100042126. Registered on 14 January, 2021, http://www.chictr.org.cn/edit.aspx?pid=42669&htm=4
FAKTOR YURIDIS YANG MEMPENGARUHI PENAMBAHAN JUMLAH DAFTAR PEMILIH KHUSUS PADA PEMILU 2019 DI KABUPATEN TULUNGAGUNG
Authors: Shobahah Nurush , Rifai Much Anam
Published: August 2021

The relatively high number of Registered Special Voters in the 2019 Election became a problem. Since Registered Special Voters are people who qualifi as voters but they are not listed in the Registered Fixed Voters, it can be concluded that the voter registration conducted by General Election Comission is not as qualifying as it should be. However, there is an opinion that basically Registered Special Voters are not pure as it is listed. Some voters have already been registered as Registered Fixed Voters. Through this qualitative descriptive research with a case-approach, the research purpose is to reveal factors making people as Registered Special Voters in Tulungagung Regency. The result was that there were 23 percent of voters in the Registered Special Voters in Tulungagung who were already registered as Registered Fixed Voters. They are registered as Registered Special Voters presumably due to the following factors: First, problem arised when voters are mistakenly put in the polling station. Second, problem due to administrative error in recording the presence of the voters. Third, problem caused by the residence exchange. In order to solve this problem, electoral regulation reconstruction is needed, especially in relation to updating registered voter and/or voting-count mechanisme.

 Keywords: Election, Registered Special Voters, Reconstructing Regulation.
POLIGAMI DI DUNIA ISLAM
Authors: Hakim Abdurrahman , Aibak Kutbuddin
Published: August 2021

This paper compares the legal verses of polygamy in Saudi Arabia, Pakistan, and Indonesia. Apart from the controversy considered as detrimental and degrading to women, term of polygamy is not as easy as Westerners think in the license process. This study compares legal verses, licensing procedures, fines, either imprisonment or punishment, to husbands who violate the applicable regulations. Therefore, this research serves as evidence talthough polygamy is permitted, the procedures and requirements regulated by Saudi Arabia, Pakistan, and Indonesia contain elements of protection and respect for women. The method is qualitative with the library type. This research is classified as a co-comparative approach, which is a study that compares one legal case between several countries. The results are: 1) in Saudi Arabia, polygamy is still based on the classical Islamic fiqh school of Imam Hambali. Therefore, polygamy is not so much a concern in parliament that there is no legal reform there. As a result, polygamy is very free and tends to harm women. 2) in Pakistan, polygamy is also based on Islamic teachings, it's just that there is a legal reform that states that there must be written permission from the Arbitration Council if a husband wants to do polygamy. 3) in Indonesia, polygamy is very complicated, because basically the Marriage Law No. 16 of 2019 concerning Marriage contains the principle of monogamy. In addition, polygamy can be carried out by the husband if  he has received permission from the wife and the board of judges in court.
Administering Shingles Vaccine Prior to Initiation of Biologics Therapy
Authors: Ryan Alicia , Soo Alex , O’Rourke Niall , Nasrudin Ayub , Khan Dan , Lafferty Fiona , Kelly James , Byrne Nicola , Semenov Serhiy
Published: August 2021

BackgroundShingles, also known as herpes zoster, is a viral infection caused by the varicella zoster virus. The classic feature is a painful dermatomal rash. Although the disease is often self-limiting, complications such as postherpetic neuralgia can cause long-lasting morbidity. Patients who are immunosuppressed are more susceptible to developing shingles, and disease may be more severe. The purpose of this paper is to systematically review the evidence for prophylactic use of the shingles vaccine prior to initiating biological therapy.
Objectives To evaluate the evidence for shingles vaccine prophylaxis prior to initiating biologics therapy.
Methods We performed a comprehensive Boolean search of PubMed and EMBASE for the following terms: prophylaxis, prior, shingles vaccine, varicella zoster, infliximab, biological therapy, guidelines. Eligible studies met the following criteria: published in English, published since 2000, any shingles vaccine type and dose, vaccine monotherapy, autoimmune disease biological therapy. There was no specific target for gender, age or population. Randomised controlled trials, meta analyses and systematic reviews were included. Studies were excluded based on the following criteria: duplicate studies, non-English language papers, papers not addressing autoimmune disease therapy, clinical trials and cohort studies.
Results 32 studies met the search criteria, of which 8 were selected for the literature review. All studies had generally differing conclusions as to whether shingles vaccination in autoimmune patients undertaking biologic therapy was safe and effective.
Conclusions Patients with autoimmune disease should be considered for the herpes zoster vaccine prior to initiating biological therapy, though the specifics of vaccination administration is unclear. Our findings support the use of the live attenuated vaccine, Zostavax or the non-live vaccine, Shingrix. However, further research is required to evaluate specific autoimmune conditions and specific biological agents with a view to the formulation of national clinical guidelines on the use of the herpes zoster vaccine in the immunocompromised.
Value of Newborn Screening Programs for Severe Combined Immunodeficiency
Authors: Pirozzi Elisa
Published: August 2021

Severe Combined Immunodeficiency Disease (SCID) is life-threatening disease of infancy and childhood characterized by recurrent infections and failure to thrive. Given the modern medical progress made available for treating SCID, early identification of these children is paramount to their wellbeing and overall survival into adulthood. Newborn screening (NBS) programs provide the opportunity to identify SCID patients before life-threatening infections can manifest. The T-cell receptor excision circles (TRECs) assay currently used for SCID screening has been shown to satisfy all parameters of an effective screening test.  Its widespread use is indicated by the time-sensitive nature of the disease, its efficacy in reducing morbidity and mortality in these patients, and the cost-effectiveness of prompt recognition versus long-term management. While immensely beneficial, screening tests still hold limitations that require analyzing. Follow-up measures for SCID identification programs have identified ambiguity and inconsistency among testing algorithms across facilities and technical errors that have causes inaccurate results. Considering fewer than 20% of SCID patients report a positive family history and the lethal consequences of disease if left untreated, a screening program is a highly valuable tool for early diagnosis and prompt intervention.
BATI MUHAYYİLESİNDE TÜRKOFOBİK UNSURLAR VE ÖTEKİLEŞTİRME SÜRECİ
Authors: YARDIM Müşerref
Published: August 2021

Batı'da oluşan ve bugün hala kullanılmaya devam edilen Türk imajının kökenleri tarihsel gelişmelerle bağlantılıdır. Her ne kadar Türklerin Avrupa'ya yerleşmeleri İkinci Dünya Savaşından sonra olsa da Batı'nın Türklerle tanışması eski tarihlere dayanmaktadır. Farklı tarihlerde Batılılar ve Türkleri karşı karşıya getiren savaşlar ve özellikle Haçlı Seferleri sonrası Türkler hakkında olumsuz imaj oluşmaya başlamaktadır. Oryantalist düşünce çerçevesinde Türkler, Doğulu ve Müslüman olarak tanımlandığından Batı'nın algısında Türk ve Müslüman kavramlarının aynı anlamı taşıdığı görülmektedir. İlişkiler, "Türkler her şeyden önce bir düşmandır" algısı üzerine kurulmaktadır. Batı dillerinde Türkler hakkında oluşmuş ötekileştirici ve küçümseyici türkofobik deyimler de tarihten gelen Türk korkusuna vurgu yapmaktadır. Türkiye ve Türklere yönelik önyargılar aynı zamanda Türkiye'nin Avrupa Birliğine üyelik sürecini de etkilemektedir.
An Empirical Analysis of The Impact of Islamic Banking on Real Output in Indonesia
Authors: Sasana Hadi , Ramdani Deni , Novitaningtyas Ivo
Published: August 2021

Abstract: The role and contribution of Islamic finance on economic growth in Indonesia has increased gradually and steadily. This is because the Islamic economy's universal and comprehensively basic principle is the primary foundation of Islamic banking. This research aimed to analyze the role of Islamic Banking on Indonesia's real sector during 2007.01 – 2016.04. This study used the Vector Error Correction Model (VECM) as a tool to analyze secondary data. The result showed that in Indonesia, sharia deposit positively and significantly influenced actual output in the short term. In addition, in the long-term, sharia financing positively and significantly influenced actual output. Moreover, Granger Causality Test proved the occurrence of one-way causality between actual output and inflation. Thus, Islamic banking can encourage actual output in Indonesia. The results of this study become a consideration for stakeholders and policymakers to pay more attention to strategies and policies that support economic growth in Indonesia.Abstrak: Perkembangan keuangan syariah di Indonesia semakin meningkat setiap tahunnya. Prinsip-prinsip dasar ekonomi syariah yang universal dan komprehensif merupakan landasan utama perbankan syariah. Tujuan penelitian ini untuk menginvestigasi peran perbankan syariah terhadap sektor riil di Indonesia selama periode 2007.01 – 2016.04. Penelitian ini menggunakan Vector Error Correction Model (VECM) sebagai alat untuk menganalisis data sekunder. Hasil penelitian menemukan bahwa dalam jangka pendek deposito syariah berpengaruh positif dan signifikan terhadap output rill. Selain itu, dalam jangka panjang pembiayaan syariah berpengaruh positif dan signifikan terhadap output riil di Indonesia. Lebih lanjut, Uji Kausalitas Granger membuktikan terjadinya kausalitas satu arah antara output riil dan inflasi. Dengan demikian, perbankan syariah mampu mendorong output riil di Indonesia. Hasil penelitian ini menjadi bahan pertimbangan bagi para pemangku kepentingan dan pengambil kebijakan untuk lebih memperhatikan strategi dan kebijakan yang mendukung pertumbuhan ekonomi di Indonesia.
Determinant Market Power of Sharia Banking in Indonesia
Authors: Fauzi Muchamad
Published: August 2021

Abstract: This study aims to analyze the level of market power and determinants of Sharia banking in Indonesia, using the Bresnahan-Lau model approach. This study is explanatory research using a quantitative approach. The data used are secondary, including one dependent variable, namely Market Power (MP), with five independent variables, namely Equivalent Rate (ER), 3-month Bank Indonesia Syariah Certificates (SBIS3), Number of Branches (CAB), Gross Domestic Product (GDP) ), Inflation (INF), and one control variable that is the historical aspect (MPt-1) by using time series data on the annual financial statements of Bank Syariah Mega Indonesia (BSMI), Bank Syariah Mandiri (BSM), Bank Muamalat Indonesia (BMI). The results show market power in the Sharia banking industry in Indonesia, with a significance level of ER and GDP interaction testing of 0,000.Abstrak: Penelitian ini bertujuan untuk menganalisis tingkat market power serta determinan market power perbankan syariah di Indonesia, dengan menggunakan pendekatan Bresnahan-Lau model. Penelitian ini merupakan penelitian explanatory research menggunakan pendekatan kuantitatif. Sumber data yang digunakan adalah data sekunder, meliputi satu variabel tergantung yaitu Market Power (MP), dengan lima variabel bebas yaitu Equivalent Rate (ER), Surat Berharga Indonesia Syariah 3bulan (SBIS3), Jumlah Cabang (CAB), Produk Domestik Bruto (PDB), Inflasi (INF), serta 1 variabel kontrol yaitu aspek historis (MPt-1). menggunakan data time series laporan keuangan tahunan Bank Syariah Mega Indonesia (BSMI), Bank Syariah Mandiri (BSM), Bank Muamalat Indonesia (BMI). Hasilnya menunjukkan bahwa terdapat market power pada industri syariah banking yang berkedudukan di Indonesia dengan tingkat signifikansi pengujian interaksi ER dan PDB sebesar 0,000.
Comparing Credit Risk in Islamic and Conventional Banking Using Bank-Level Panel Data
Authors: Susamto Akhmad Akbar , Octavio Danes Quirira , Wardani Dyah Titis Kusuma
Published: August 2021

Abstract: This paper investigates if there is a difference in the level of the credit risk of Islamic as compared to the level of credit risk of conventional banks. This paper further investigates the importance of various credit risk determinants and possible differences in how such determinants affect credit risk in Islamic and conventional banking industries. This paper employs dynamic panel regressions using system GMM estimators. The sample includes 11 Islamic and 95 conventional banks in Indonesia throughout 2003-2018. Based on the results, it is concluded that there is no difference in the level of the credit risk of Islamic as compared to that of conventional banks. It is also concluded that credit risk is significantly affected by current and lagged asset size, lagged financing, current profitability, lagged economic growth, and current inflation. The effect of lagged financing, current profitability, and lagged economic growth is different in Islamic and conventional banking.Abstrak: Makalah ini menganalisis apakah terdapat perbedaan antara tingkat risiko kredit pada perbankan syariah dan tingkat risiko kredit pada perbankan konvensional. Makalah ini selanjutnya juga menganalisis signifikansi faktor-faktor yang diduga mempengaruhi risiko kredit dan kemungkinan perbedaan pengaruh faktor-faktor tersebut terhadap risiko kredit pada perbankan syariah dibandingkan pada perbankan konvensional. Makalah ini menggunakan regresi panel dinamis dengan system generalized method of moments (GMM) estimator. Sampel dalam makalah ini mencakup 11 bank syariah dan 95 bank konvensional di Indonesia selama periode 2003-2018. Berdasarkan hasil analisis, dapat disimpulkan bahwa tidak terdapat perbedaan perbedaan antara tingkat risiko kredit pada perbankan syariah dan tingkat risiko kredit pada perbankan konvensional. Begitu pula, dapat disimpulkan bahwa risiko kredit secara signifikan dipengaruhi oleh ukuran aset tahun ini dan tahun lalu, pembiayaan tahun lalu, profitabilitas tahun ini, pertumbuhan ekonomi tahun lalu dan inflasi tahun ini. Pengaruh pembiayaan tahun lalu, profitabilitas tahun ini, dan pertumbuhan ekonomi tahun lalu, secara khusus berbeda pada perbankan syariah dibandingkan pada perbankan konvensional.
ZISWAF Digital Payment as An Effort to Reach Millennials
Authors: Hasyim Fuad , Awwal Muhammad Al-Farido , Al Amin Nur Hidayah
Published: August 2021

Abstract: ZISWAF is an Islamic-led fundraising instrument aimed at wealth distribution. The existence of technological developments allows the adaptation of payments with all its acceleration. This study aims to determine the digital payment strategy to maximize ZISWAF’s revenue potential in Indonesia. This study uses the TAM, and TPB modification approaches. The methodology used is structural equation modeling (SEM) with a partial least square (PLS) approach. The sample used is the Y generation as a representation of the millennial generation. The results showed that all the variables forming the TAM theory (perceived usefulness, perceived ease of use, attitude) and all the variables creating the TPB theory (subjective norms and perceived behavior control) significantly affect the Intention (INT) of individuals pay for online ZISWAF (sig. 0.05, α=5%). Furthermore, attitude is a mediating variable in a partial/ quasi modification model that links perceived usefulness (PU), perceived ease of use (PEoU) to Intention (INT) (VAF=49.87%).Abstrak: ZISWAF adalah instrumen pengumpulan dana yang dipelopori Islam dengan tujuan untuk distribusi kekayaan. Adanya perkembangan teknologi memungkinkan adaptasi pembayaran dengan segala akselerasinya. Penelitian ini bertujuan untuk mengetahui strategi pembayaran digital untuk memaksimumkan potensi pendapatan ZISWAF di Indonesia. Penelitian ini menggunakan pendekatan modfikasi TAM dan TPB. Metodologi yang digunakan adalah structural equation modeling (SEM) dengan pendekatan partial least square (PLS). Sampel yang digunakan merupakan generasi Y sebagai representasi generasi milenial. Hasil menunjukkan seluruh variabel pembentuk teori TAM yakni perceived usefulness (PU), perceived ease of use (PEoU) dan attitude (ATT) dan seluruh variabel pembentuk teori TPB yakni subjective norms (SN) dan perceived behavior control (PBC) berpengaruh terhadap intention (INT) individu dalam membayar ZISWAF secara online (sig. 0.05, α=5%).  Attitude (ATT) merupakan variabel pemediasi dalam model modifikasi yang bersifat partial/ quasy yang menghubungkan perceived usefulness (PU), perceived ease of use (PEoU) terhadap intention (INT) (VAF=49.87%)
Uso seguro e racional de produtos naturais e fitoterápicos:
Authors: Dantas-Medeiros Renato , Bezerra Alan Soares , De Oliveira Renata Borges , De Lima Juliana Bessa Figueiredo , Da Silva Luanna Valéria , Oliveira Gilberto , Zucolotto Silvana Maria
Published: August 2021

O presente artigo é resultante de um projeto de extensão que objetivou a criação do perfil @fitoterapia.com.ciencia no Instagram como ferramenta didática para promover a participação e interação entre profissionais de saúde e a sociedade sobre o tema “Uso seguro e racional de produtos naturais e fitoterápicos". O perfil soma um total de 5.550 seguidores e até a presente data foram realizadas 139 publicações sobre conceitos, atualizações, Fake News e eventos na área de produtos naturais e fitoterápicos. Semanalmente o perfil tem um alcance superior a 2.400 visualizações e um total de 5.617 impressões. Em conclusão, observou-se que o uso do Instagram foi uma ferramenta tecnológica promissora para a comunicação virtual na divulgação de informações científicas seguras aos profissionais de saúde e à sociedade de forma simples, acessível e interativa.
Aile sağlığı merkezine başvuran hastalarda Helicobacter pylori sıklığı
Authors: SAKMAN Abdullah , BAYRAM Yasemin , PARLAK Mehmet , GÜDÜCÜOĞLU Hüseyin
Published: August 2021

Giriş: H. pylori’nin görülme sıklığı, özellikle düşük sosyo-ekonomik durum, sağlık önlemlerinin yetersizliği, toplu yaşam koşulları ve su kaynaklarındaki sorunlarla ilişkili olarak artış göstermektedir. H. pylori ile enfekte ve aşırı asit salgılanması olan kişiler mide ülseri, mide kanseri ve duodenum ülseri açısından büyük risk taşırlar. Çalışmada, Aile Sağlığı Merkezine başvuran erişkin hastaların dışkı örneklerinde H. pylori antijen varlığı araştırılmıştır. H. pylori tespit edilen kişilerin, Gastroenteroloji Kliniğine yönlendirilmesi ve ileri tetkikler uygulanması neticesinde, teşhisin kesinleştirilmesi ve erken teşhis konulması suretiyle, tedavi planına katkı sağlanması amaçlanmıştır. Yöntem: Çalışma, Kasım 2016-2017 tarihleri arasında Van il merkezinde bulunan Aile Sağlığı Merkezimize başvuran hastalardan, rastgele seçilen 189’u kadın ve 129’u erkek olmak üzere 17-83 yaş aralığındaki (yaş ort. 45) toplam 318 kişi üzerinde yürütülmüştür. Dışkıda H. pylori antijenlerini tespit etmek için, H. pylori hızlı antijen test (One Step Rapid Test, Çin) kullanılmıştır. Çalışma sonunda hastaların gastrik şikâyetlerinin olup/olmadığı, H. pylori mikrobuna etki eden ilaç kullanımının olup-olmadığı cinsiyet, yaş ve test sonucu bilgilerinin SPSS programı yardımı ile istatistik çalışması yapılarak sonuçlar değerlendirilmiştir. Bulgular: Çalışmamızda, 75’i (%58) kadın ve 54’ü (%42) erkek olmak üzere 129 (%41) kişinin dışkısında H. pylori pozitif olarak tespit edilmiştir. Cinsiyetlerin kendi içindeki test sonucu, pozitifliği oranı açısından; kadınların %40’ında ve erkeklerin %42’sinde H. pylori pozitif olarak tespit edilmiştir. Cinsiyetler arasında farklılık, istatistiksel olarak anlamlı bulunmamıştır. H. pylori’nin her yaşta görülebileceği, H. pylori antijen pozitifliğinde yaş ilerlemesine paralel olarak artış gösterdiği tespit edilmiştir. Test sonucu pozitif olanların 91’inde (%70,5) gastrik şikâyetlerin olduğu gözlenmiştir Proton pompa inhibitörü kullanımının (PPI), kadınlarda erkeklere göre daha fazla olduğu görülmüştür. Sonuç: Ülkemizde yapılmış diğer çalışmalar ile kıyas edildiğinde, bu çalışmamızda H. pylori pozitifliğinin düşük olması önemlidir. Gastrik şikâyeti olan kişilerde, test pozitiflik oranı daha yüksektir ve PPI kullanımının H. pylori eradikasyonu üzerinde etkisi açıktır.
Are Patients Losing Their Chance of Survival Because They Are Unaware of Having a Myocardial Infarction? A Phenomenological Study
Authors: ÇİÇEK Hatice , BAYRAK Damla , TOSUN Nuran
Published: August 2021

Objective: The aim of this study was to explore the experiences of patients with myocardial infarction and their relatives. Methods: This qualitative and phenomenological study was conducted with 20 patients hospitalized due to the diagnosis of myocardial infarction and 15 relatives. A semi-structured interview form and data collection form including socio-demographic characteristics were used. The data of the study were collected using the in-depth individual interview method and were assessed using the phenomenological approach developed by Colaizzi. The researchers analyzed statements of the participants regarding their experiences and prepared categories and themes. Results: Three categories and seven themes emerged as a result of the data analysis. These categories included symptom experiences, views about death, transportation to health care facility. The statements of participants revealed that patients experienced various symptoms including sweating, chest pain, gastrointestinal system symptoms, shortness of breath, yellow and purple skin tone. It was also determined that they generally had a lack of knowledge about myocardial infarction symptoms, could not associate symptoms with myocardial infarction, attributed myocardial infarction to other matters, used various ineffective methods to cope with symptoms. The majority of the patients arrived at the health care facility by self-transport and some patients even drove themselves to the health care facility. Conclusion: Participants had a lack of knowledge about the symptoms of myocardial infarction and appropriate transport to the health care facility, for example, utilizing an ambulance. This, in turn, prolongs the period of prehospital delay that has an effect on the chance of survival and receiving an effective treatment.
Traditional Mosque Architecture: Portrayal of society sociology
Authors: Sujak Ilyana , Mazlan Ida Marlina , Azman Nor Syawallina , Alias Nur Ulfah Awatif Umairah
Published: August 2021

Mosque architecture built to reflect the physical environment in which Muslim society manifest their beliefs and behaviours. This research attempts to discover the portrayal of society sociology in traditional mosque architecture. It analyses the social beliefs and behaviours manifestation in the design and construction of the traditional mosque. The case study method is applied, consisting of on-site building measurement, on-site observation, and interview with expert informants on the old Kampung Tuan Mosque. The findings from this research conclude a significant portrayal of society sociology found in the aspect of design and construction of the mosque.
Keywords: Architecture, Traditional Mosque, Society, Sociology
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6i17.2804
Role of Diffusion and Socio-cognitive towards Intention to use Health Portal among Health Consumers in Malaysia
Authors: Mohd Tobi Siti Noraini , Kassim Erne Suzila , Ghazali Norfazlina , Kadang Hendrikus
Published: August 2021

The paper aims to examine the critical success factors that influence the attitude of health consumers and their intention to use the national health portal (MyHEALTH Portal). The study was constructed from two behavioral models; Diffusion of Innovation and Theory of Reasoned Action. It utilized an online survey hosted on the official portal website with a convenience sampling technique of 223 respondents. Results showed complexity did not significantly contribute towards attitude, while trialability and relative advantage showed significant contributions. Meanwhile, attitude influenced health consumers' intention to use the portal, while subjective norms indicated otherwise.  
Keywords: Diffusion; socio-cognitive; health portal, health consumer
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6i17.2809
Employers’ Perceptions in Hiring Decisions Pertaining to People with Disability
Authors: Mat Yusoff Norhayati , Saripin Sofia Sarmimi , Muhammad Rosmaliza , Sudono Agus
Published: August 2021

This study aimed to analyze hotels employers’ perceptions in hiring decisions on people with disability (PWD). A total of 35 samples out of 72 employers among the 4 and 5-star hotels in Kuala Lumpur were selected based on the census sampling method. It is found that employer perceptions to hire PWDs are influenced by gender, type of disability, work performance concerns, and co-worker and guest concerns. Interestingly, employers are discovered to have more positive perceptions towards female PWDs. They are also interested to hire PWDs who meet the requirements of the job regardless of their disability.
Keywords: Employers’ perceptions; hiring decisions; people with disability; hotel industry.
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6i17.2810
Reward and Satisfaction: Keeping hospitality employees loyal
Authors: Mazlan Nurfatihah , Sumarjan Norzuwana , Nazlan Nadia Hanin , Suhartanto Dwi
Published: August 2021

Employee loyalty is influenced by job satisfaction which stems from various factors such as reward, work environment, or leadership. Due to the importance of loyal employees in maintaining the competitive advantage of organisation, this study examines how reward in upper-upscale hospitality organisations in Selangor influences job satisfaction and employee loyalty. Structural equation modelling using SmartPLS found significant paths between financial rewards, job satisfaction, and employee loyalty. The same could not be said for non-financial rewards. The findings provide insights into how hoteliers can strategise their financial reward and maximise non-financial reward usage to retain the employees, especially during turbulences.
Keywords: Financial reward; non-financial reward; job satisfaction; employee loyalty
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6i17.281
Ecovillages, Environment and Sustainability Practice
Authors: Rohana Sham , Mohammad Imran , Csabai Doleres , Nik Mohammad Nik Mastura
Published: August 2021

This paper focuses on the Ecovillages operation, environment, and sustainable practices implemented among the current operating Ecovillages worldwide. The main objective is to examine the critical factors affecting the sustainability of Ecovillages and their practice in managing their surroundings and environment. This study proceeds with a quantitative research method to further investigate the sustainability practice issues among the existing Ecovillages in the world. The data were collected through a self-administered questionnaire using an online platform. This study test four independent variables, namely energy efficiency, organic food, telework, and social media, towards the sustainability practice of the Ecovillages operation worldwide.
Keywords: Ecovillages; Environment; Sustainable; Practice
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6i17.2819
Recovery of Corrupt Assets via Unexplained Wealth Order
Authors: Abdul Raof Nurazlina binti Abdul Raof , Abdul Aziz Norazlina , Abdul Raof Nurazhani
Published: August 2021

The Unexplained Wealth Order in the United Kingdom allows the confiscation of corruptions' assets without conviction. The burden of proof lies on the asset owner to prove its legitimate source. This study addresses the applicability of the Unexplained Wealth Order in Malaysia. A qualitative methodology based on doctrinal study supported by an opinion of an academician in the United Kingdom is adopted. Analysis of the Unexplained Wealth Order is required as part of civil means to recover the proceeds of corruption in Malaysia. The study may assist the stakeholders in Malaysia in understanding the concept of the Unexplained Wealth Order.
Keywords: corruption; civil mechanism; proceeds of corruption; recovery of assets
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6i17.2828
The Influence of Socio-Economics on Travel Behavior of Public Transportation in Malaysia
Authors: Ngah Rohana , Abdullah Jamalunlaili , Khalique Muhammad , Goyipnazarov Sanjar Bakhodirovich
Published: August 2021

This paper explores the influence of socioeconomics on travel behavior among public transport commuters to increase modal share. A face-to-face survey was carried out, and 904 usable questionnaires were analyzed using SPSS. The findings showed that level of education strongly influences travel behavior while there is not much difference in gender, age, income, and occupation. However, the categories in the groups provide good information relating to travel behavior. Suggestions and recommendations are provided to help the public transport service provider setting more strategic plans to encourage more individual riders to switch to public transport and sustain existing users.
Keywords: Socio-economics, travel behavior, public transport
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI:  https://doi.org/10.21834/ebpj.v6i17.2833
COVID-19 Pandemic: Youth Compliance Behaviors towards Movement Control Order (MCO)
Authors: Zur Raffar Izzah Nur Aida , Ibhrim Zuriani , Mujani Wan Kamal , Hayati Najmi
Published: August 2021

This analysis aims to investigate Muslim youths' compliance behavior towards the Standard Operating Procedures throughout the Malaysian government's Movement Control Order, which was implemented to contain and mitigate the cases of the COVID-19. The design of this study is a survey study using a questionnaire instrument on 545 respondents who were purposefully selected among Muslim youth aged 15 to 30 years in Malaysia. Meanwhile, the data was analyzed using descriptive statistical techniques using IBM SPSS. The findings of this study can provide information to the youth, particularly regarding the COVID-19 prevention procedure and the needs of following it.
Keywords: COVID-19 pandemic, behavior, youth, Movement Control Order (MCO).
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6i17.2850
Environmental Management Accounting System and Value Creation: An institutional perspective
Authors: Mat Yusoh Nirman Noor Afiqi , Tuan Mat Tuan Zainun , Abdullah Azizah , Marimuthu Ferina
Published: August 2021

The emergence of environmental issues has increased environmental protection awareness among society and pushed organizations to become environmentally responsible. Many companies currently consolidate environmental matters into their corporate strategic plan by adopting a comprehensive Environmental Management Accounting System (EMAS) to create more value. However, a lack of understanding on the institutional pressures persuading EMAS adoption within the organizations has reduced the urgency for the company to adopt the EMAS. This paper aims to explain the management's behavioral issues towards accepting EMAS adoption and how this behavior would lead to value creation.  
Keywords: Environmental Management Accounting System (EMAS), behavioral barriers, value creation, institutional theory
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6i17.2866