bluuebunny/crossref_metadata_2025 huggingface dataset:
On the issue of dynamic loading of the Kirovets K-4 tractor transmission
Authors: Василевский М.Р. , Александров В.А.
Published: November 2020

Данное исследование имеет прикладной характер и направлено на решение проблемы, возникшей на АО «Петербургский тракторный завод» (далее – АО «ПТЗ»). Была поставлена задача – теоретически определить динамическую нагруженность трансмиссии трактора Кировец К-4, чтобы исключить возможность неправильной конструкторской компоновки трансмиссии трактора, вследствие чего могло бы возникать разрушение карданного вала между двигателем внутреннего сгорания и коробкой передач. Исследование проведено на трехмассовой математической модели. Математической описание составлено в форме уравнений Лагранжа II рода.

This research is of a direct applied nature and is aimed at solving the problem that arose at JSC «Peterburgsky Traktotny Zavod» (hereinafter referred to as JSC "PTZ"). The task was set to theoretically determine the dynamic load of the Kirovets K-4 tractor transmission, in order to exclude the possibility of incorrect design layout of the tractor transmission, in consequence of which, there could be a destruction of the driveshaft between the internal combustion engine and the transmission. The study was conducted on a three-mass mathematical model. The mathematical description is in the form of Lagrange equations of the second kind.
„Handle, wie Dir Dein Dämon vorschreibt!“
Authors: Smiljanić Damir
Published: November 2020

U članku će biti riječi o burnom životu njemačkog pisca, esejista i satiričara Oskara Panizze (1853. – 1921.), kao i o njegovu sukobu sa zakonom i vlašću, zbog čega je morao provesti godinu dana u zatvoru. Balansirajući na granici između stvarnog i iluzornog, genijalnosti i ludila, ovaj karizmatični autor proživio je život pun proturječja: započeo je kao liječnik za mentalne bolesti, postao pisac, a svoju životnu odiseju okončao kao pacijent u sanatoriju. Nadovezujući se na Maxa Stirnera, Panizza je zastupao iluzionizam kao legitiman pogled na svijet: halucinacija je ono stvarno, a stvarnost samo umišljena. U članku će se pokazati da se ne radi o stvaratelju pomračenog uma, već o nekome tko je preispitivao granicu između normalnog i nenormalnog, u izvjesnom smislu anticipirajući nadolazeću kritiku normativnih postavki institucionalne psihijatrije.
Wang Yangming’s Notions of Primary Knowledge and Primary Ability
Authors: Ott Margus
Published: November 2020

Rad najprije utvrđuje da iz pojma prvobitnog znanja (liangzhi 良知) Wanga Yangminga王陽明 (1472. – 1529.) ne slijedi subjektivni idealizam te da je vezan za transcendentalnu subjektivnost u smislu fenomenologije. Zatim, raspravlja se o pitanju ima li Wang pojam prvobitne sposobnosti (liangneng 良能). Argumentira se da se može naći u dvije glavne Wangove teme – »znanje i radnja jedno su« (zhixing heyi 知行合一) te »razmatrati Nebo i Zemlju i mnoštvo stvari kao jedno (rizomatično) tijelo« (以天地萬物為一體) ili ih smatrati »izvorno jednim s mojim (rizomatičnim) tijelom« (本吾一體). Pokazuje se da su prvobitno znanje i sposobnost dva aspekta isto fenomena. Istinito je na razini virtualnog »rizomatskog tijela« (ti 體), a ne na razini stvari razmatranih kao potpuno oblikovane
i aktualizirane (xing 形), kako se pojavljuju u empirijskom umu, zamagljeni žudnjama (yu 欲) koje postaju fiksirane na razini aktualnog. Te se žudnje mogu razriješiti putem »proširenja (prvobitnog) znanja« zhi
(liang)zhi 致(良)知. Usporedni pojam »proširenja (prvobitne) sposobnosti« (zhi liangneng 致良能), koji Wang Yangming ne koristi, može se unijeti u sustav.
Rorty’s Metaphilosophy and the Critique of Epistemology
Authors: Pešić Boško , Uzunić Mislav
Published: November 2020

Richard Rorty suvremeni je filozof analitičke filozofijske tradicije koji je svoje karijerno usmjerenje skrenuo na metafilozofijsku kritiku epistemologije. Osnova Rortyjeve kritike leži u njegovu odbijanju kartezijanskog dualizma, što ga dovodi do zaključka da je svaki pokušaj dosezanja istine putem znanja o bitima osuđen na propast. Umjesto toga, Rorty argumentira u korist traženja razumijevanja putem razgovora – postupka koji zove eidifikacija – koji bi vodio do potpunog uklanjanja epistemologijskog problema znanja. Njegov metafilozofijski poduhvat želi
hermeneutikom zamijeniti epistemologiju i time je uspostaviti kao temeljni filozofijski pristup. Međutim, Rorty nedovoljno naglašava važnost istine za hermeneutiku. To je manjak koji će ovo istraživanje pokušati nadoknaditi da bi pokazalo kako je Rortyjev skepticizam po pitanju istine problematičan za njegovu vlastitu poziciju bliskosti s hermeneutikom. Nakon opisivanja Rortyjeva metafilozofijskog programa, temeljno uspostavljenog u Filozofija i ogledalo prirode, rad istražuje (ne)kompatibilnost Rortyjeve pozicije s hermeneutikom, prvenstveno s Gademerovom. Dolazimo do zaključka da bi pogrešno bilo smatrati Rortyjevu (meta)filozofiju izdankom hermeneutike ili potpuno kompatibilnu s njome, uzimajući u obzir da prednost pred istinom daje društvenim problemima.
Intercomparing the robustness of machine learning models in simulation and forecasting of streamflow
Authors: Loganathan Parthiban , Mahindrakar Amit Baburao
Published: November 2020

The intercomparison of streamflow simulation and the prediction of discharge using various renowned machine learning techniques were performed. The daily streamflow discharge model was developed for 35 observation stations located in a large-scale river basin named Cauvery. Various hydrological indices were calculated for observed and predicted discharges for comparing and evaluating the replicability of local hydrological conditions. The model variance and bias observed from the proposed extreme gradient boosting decision tree model were less than 15%, which is compared with other machine learning techniques considered in this study. The model Nash–Sutcliffe efficiency and coefficient of determination values are above 0.7 for both the training and testing phases which demonstrate the effectiveness of model performance. The comparison of monthly observed and model-predicted discharges during the validation period illustrates the model's ability in representing the peaks and fall in high-, medium-, and low-flow zones. The assessment and comparison of hydrological indices between observed and predicted discharges illustrate the model's ability in representing the baseflow, high-spell, and low-spell statistics. Simulating streamflow and predicting discharge are essential for water resource planning and management, especially in large-scale river basins. The proposed machine learning technique demonstrates significant improvement in model efficiency by dropping variance and bias which, in turn, improves the replicability of local-scale hydrology.
Value of a made-in-Ontario management system standard for municipal wastewater and stormwater utilities
Authors: Tovilla Edgar
Published: November 2020

This paper builds on previous research to address the question of whether there is practical value for a made-in-Ontario municipal management system standard (MSS) for wastewater and stormwater related activities, in addition to the Drinking Water Quality Management System Standard (DWQMS) that is already statutorily required. This research specifically addressed the questions: is there value in a mandatory or voluntary MSS; are there neutral, positive, or negative effects of having an MSS; and what standard is more adequate? Through a focus group method, this research finds evidence in support of and wide recognition of the practical value an MSS in assisting municipalities in meeting their environmental objectives, addressing property damage risks, providing an additional mechanism of public accountability, and improving alignment with the legal structure. It was also apparent that there is no political appetite in the provincial government to embark on a mandated MSS, so the preferred option at this time appears to be a provincially endorsed, voluntary, sector-specific standard for wastewater and for stormwater, which could constitute a catalyst to boost voluntary uptake of MSS by small to medium municipalities (as is already occurring with large municipalities). This standard could be based on a customized variation of the ISO 14001 and DWQMS.
Storm at the Time of Corona: A Glimpse at the Current Understanding and Therapeutic Opportunities of the SARS-CoV-2 Cytokine Storm
Authors: Torabi-Rahvar Monireh , Rezaei Nima
Published: November 2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to severe disease in some
cases, leading to acute respiratory distress syndrome, multi-organ failure, and death. This severe phenotype
seems to be associated with a cytokine storm and immune dysregulation. Increased pro-inflammatory cytokines
and CD14+CD16+ inflammatory monocytes, lymphopenia, and decreased levels of regulatory T cells are some
of the immunological features that are seen in patients with SARS-CoV-2. As the outcome of SARS-CoV-2 is
influenced by both viral virulence and dysregulated inflammatory response, a combination therapy approach
using antiviral drugs plus anti-inflammatory treatments, such as corticosteroids, monoclonal antibodies against
the IL-6 and IL-1β pathways, and JAK inhibitors are under clinical trials.
Chalcone Scaffolds as Anticancer Drugs: A Review on Molecular Insight in Action of Mechanisms and Anticancer Properties
Authors: Shukla Shefali , Sood Anantpreet K. , Goyal Kartika , Singh Ambika , Sharma Vaidehi , Guliya Neha , Gulati Shikha , Kumar Sanjay
Published: November 2020

Cancer is the deadliest disease worldwide and the development of safer chemical entities to treat
cancer is one of the major challenges of medicinal chemistry. The emergence of new cases every year and the
development of multiple drug resistance against available molecular entities have turned the focus of researchers
towards natural products. Chalcones are pharmacologically active compounds, present in plants, which have been
derivatized and screened by many researchers for the treatment of cancer. Chalcones, consist of 1,3-diaryl-2-
propen-1-one, is one such class exhibiting broad anticancer activities against various cancerous cell lines.

The objective of this review article is to analyze the antitumor activity of the reported chalcones via distinct
mechanisms adopted by these molecules underlying their inhibitory activity. The primary focus of this review is
to bring the attention of researchers towards the latest and important chalcones and their derivatives having
potent anticancer activity adding their possible action of mechanisms against cancerous cell lines The recent
literature was surveyed and it was found that chalcone analogs with electron donating groups, indolyl, quinolone,
pyrazol-ol, hydroxyaminobenzamide, hydroxamic acid and pyridyl- indole groups have shown promise as
potential anticancer agents following various mechanisms. Most chalcones were found to induce significant cell
cycle arrest at G2/M phase hence leading to apoptosis. A number of synthetic chalcones exhibited higher efficacy
due to their ability of potent tubulin polymerization as well as dynamic enzyme inhibitory activity. This review is
an immense compilation of research regarding the mechanism of action of chalcones and their identification as a
promising anticancer agent for future drug developments. Thus, this review article would pave the way and
provide ample opportunities to design future generations of novel, highly efficacious anticancer molecules with
minimal toxicity.
Baricitinib in Rheumatoid Arthritis – Real World Cross-Sectional Study
Authors: Sagdeo Amol , Askari Ayman , Morrissey Hana , Ball Patrick A.
Published: November 2020

Introduction:

Rheumatoid Arthritis (RA) is the most common cause of inflammatory polyarthritis. In RA, increased circulating levels of pro-inflammatory cytokines contribute to the overall symptomatology of fatigue, pain, and joint stiffness. Baricitinib is an orally administered biologic DMARD, used in RA patients, inhibiting signaling via JAK1/JAK2 inhibition, reducing the release of pro-inflammatory cytokines.

Objective:

To explore the efficacy and tolerability for baricitinib in a local population.

Methods:

A cross-sectional study was carried out to review data of RA patients on Baricitinib from the researchers’ own clinic, since its approval in August 2017. The data was collected from an anonymized electronic patient records report. The clinical response was then classified into mild, moderate, and significant improvement.

Results and Discussion:

Overall, 27 out of 37 patients (72.9%) showed clinical improvement with baricitinib. In 9(24.3%) out of 37 patients, the dose had to be reduced to either 2mg/day or 2mg/day - 4mg/day on alternate days. In four of the 9 patients’ where the dose was reduced due to infections (UTI or sinuses), they subsequently experienced fewer infections while maintaining moderate improvement in their RA.

Conclusion:

There is a need for longer-term and larger studies to evaluate the full side effects profile of baricitinib in the local population.
Oral Mucosal Lesions and DMFT Index Assessment in Rheumatoid Arthritis Patients in Birjand, Iran, in 2018
Authors: Parvaei Parvin , Dorri-giv Afsaneh , Sharifzadeh Gholamreza , Malakimoghadam Hakimeh , Atabati Elham
Published: November 2020

Introduction:

Rheumatoid Arthritis (RA) may cause malfunction in the immune system and the inability to observe oral hygiene in patients due to physical deficits. A bacterial infection caused as such can constitute a significant risk factor for the development of systemic infection. The present study aimed to investigate the oral mucosal lesions, the DMFT index, and the Modified Gingival Index (MGI) in RA patients treated in Birjand city.

Materials and Methods:

This descriptive cross-sectional study was performed with 80 RA patients referred to rheumatology clinics of Birjand in 2018. Data were collected through observation, clinical examination, information forms, and medical records. After the patients were informed about the research purposes and signed consent forms for participation, they were examined at the rheumatology clinics. The collected data were analyzed in SPSS software (version 19).

Results:

Of the 80 patients, n = 64 (80%) had oral mucosal lesions. Dry mouth (66.3%) was the most common finding. The mean DMFT index score was 18.7.

Conclusion:

Oral mucosal lesions and the mean DMFT index score seem to be at high levels in RA patients, possibly due to the complications of the disease or the consumed medications.
Analysis of the Influence of Osteosynthesis Technique and Patient-specific Factors on the Outcome of Subtrochanteric Fracture Treatment
Authors: Schulze Christoph , Kollig Erwin , Estel Katharina , Hacke Claudia , Gutcke Andre , Bieler Dan
Published: November 2020

Objective:

The number of subtrochanteric femoral fractures will continue to grow on account of demographic developments. The treatment of choice is reduction and surgical stabilisation. Intramedullary (IO) and extramedullary (EO) techniques are available for this purpose. A final assessment has not been made of which technique is superior with regard to treatment outcome, complication rates, and revision rates. The objective of this retrospective study was to compare surgical procedures with regard to weight bearing, length of hospital stay, the occurrence of complications, and the necessity of surgical revisions.

Methods:

This retrospective study included 77 patients (74.9 ± 14.9 years; 42.9% male). Associations between surgical procedures and treatment outcomes, complications and revision rates were calculated by linear and logistic regression analysis. To investigate the effect of surgical procedure within patients with fracture type 2 B according to Russel-Taylor classification, a subgroup analysis was performed.

Results:

In case of fracture type 2 B, according to Russell-Taylor classification, EO took 80 minutes longer on average than the intramedullary technique (p = 0.001), although surgeon experience plays an important role. Common complications were more frequently associated with IO than with EO. Surgical revisions were required more often in the extramedullary group (OR 4.5; 95% CI: 0.87 – 23.19). Patients in the intramedullary group were discharged 3.4 days earlier from the hospital (p = 0.024). Older patients had a higher risk for the occurrence of complications, but BMI and the experience of the surgeon did not. Patients with intramedullary stabilisation frequently showed better postoperative weight-bearing stability.

Conclusion:

The intramedullary technique offers advantages to both patients and hospitals with regard to outcome, duration of surgery, and length of stay in the hospital. Although, extramedullary implants are less expensive, this advantage is clearly reduced by the longer duration of surgery and hospital stays.
Efficient Technique for PAPR and BER Reduction in Downlink Large Scale MU-MIMO-OFDM System
Authors: Singh Jagtar , Kedia Deepak
Published: November 2020

Background & Objective:

The Orthogonal Frequency Division Multiplexing (OFDM)
based large scale multiuser multiple input multiple output (LS-MU-MIMO) system is a preferred
choice for signal transmission because it can substantially enhance the spectral and energy efficiency
of the next-generation wireless systems. However, there are several practical issues in implementing
large multiuser-MIMO-OFDM systems and one of the critical issues is the high Peak-to-Average-
Power Ratio (PAPR). Due to the use of a large number of antennas at the Base Station (BS) of an LSMU-
MIMO-OFDM system, it requires a large number of Power Amplifiers (PAs) which are needed
to be connected to each antenna element. The high PAPR in an OFDM based LS-MU-MIMO system
results in the decrease in the efficiency of PAs and enhancement in nonlinear signal distortions. This
work is concerned with the reduction in PAPR of LS-MU-MIMO-OFDM systems using the SCFDMA
scheme for the downlink transmission. The reduction in PAPR is achieved on the basis of discrete
Fourier transform spreading (DFT-S) scheme known as DFT-SC-FDMA. The SC-FDMA
scheme can achieve the reduction in PAPR of MIMO-OFDM signal up to the level of single-carrier
transmission. Further, the reduction in PAPR is achieved with the sub mapping schemes such as localized
FDMA (LFDMA) and distributed FDMA (DFDMA), Interleaved FDMA (IFDMA).

Result:

In this work, we propose to perform jointly multiuser MMSE precoding, SC-IFDMA and antenna
reservation technique to reduce the PAPR and Bit Error Rate (BER) of the large MU-MIMO
system. To show the effectiveness of the proposed scheme in the reduction of PAPR with different
modulation techniques, subcarriers, and subcarrier mapping schemes, the results are compared with
the existing OFDM based large MU-MIMO system.

Conclusion:

The MATLAB simulation results confirm that our proposed combination of MMSE MUprecoding,
SC-IFDMA and antenna reservation technique is able to reduce PAPR and BER to a significant
extent for LS-MU-MIMO-OFDM systems.
Potential Phytotherapeutic Approaches for the Treatment of Alzheimer’s Disease: An Overview
Authors: Kaushik Chetna , Yadav Prarthna
Published: November 2020

Alzheimer’s disease is one of the most prevailing age-dependent neurodegenerative diseases
and the most common cause of dementia. The pharmacological therapies available for the disease
provide only symptomatic relief. Plants are being extensively investigated for Alzheimer’s as
they are relatively safer and cheaper. This review summarizes recent findings suggesting anti-
Alzheimer potential of the plants along with compounds or mechanisms responsible for their efficacy
and their therapeutic targets. The findings of recent studies have revealed that the plants or the
compounds isolated from them exhibit mitigative potential in Alzheimer’s disease by targeting
amyloid beta, tau protein, cholinergic pathways via various enzymes like beta secretase, gamma
secretase, acetylcholinesterase or receptors involved in these pathways. A number of putative compounds
revealed from these studies can be investigated further for the mitigation of Alzheimer’s
disease.
A Serious Game Designed to Promote Safe Behaviors Among Health Care Workers During the COVID-19 Pandemic: Development of “Escape COVID-19”
Authors: Suppan Mélanie , Catho Gaud , Robalo Nunes Tomás , Sauvan Valérie , Perez Monique , Graf Christophe , Pittet Didier , Harbarth Stephan , Abbas Mohamed , Suppan Laurent
Published: November 2020

Background

As many countries fear and even experience the emergence of a second wave of COVID-19, reminding health care workers (HCWs) and other hospital employees of the critical role they play in preventing SARS-CoV-2 transmission is more important than ever. Building and strengthening the intrinsic motivation of HCWs to apply infection prevention and control (IPC) guidelines to avoid contaminating their colleagues, patients, friends, and relatives is a goal that must be energetically pursued. A high rate of nosocomial infections during the first COVID-19 wave was detected by IPC specialists and further cemented their belief in the need for an engaging intervention that could improve compliance with COVID-19 safe behaviors.

Objective

Our aim was to develop a serious game that would promote IPC practices with a specific focus on COVID-19 among HCWs and other hospital employees.

Methods

The first 3 stages of the SERES framework were used to develop this serious game. A brainswarming session between developers and IPC specialists was used to identify the target audience and acquisition objectives. Nicholson’s RECIPE mnemonic (reflection, engagement, choice, information, play, exposition) for meaningful gamification was used to guide the general design. A common and simple terminology was used to suit the broad target audience. The game was tested on various platforms (smartphones, tablets, laptops, desktop computers) by different users during each development loop and before its final release.

Results

The game was designed to target all hospital staff who could be in direct contact with patients within the Geneva University Hospitals. In total, 10 acquisition objectives were defined by IPC specialists and implemented into the game according to the principles of meaningful gamification. A simple storyboard was first created using Microsoft PowerPoint and was progressively refined through multiple iteration loops. Articulate Storyline was then used to create two successive versions of the actual game. In the final version, a unique graphic atmosphere was created with help from a professional graphic designer. Feedback mechanisms were used extensively throughout the game to strengthen key IPC messages.

Conclusions

The SERES framework was successfully used to create “Escape COVID-19,” a serious game designed to promote safe IPC practices among HCWs and other hospital employees during the COVID-19 pandemic. This game can be obtained free of charge for research and educational purposes. A SCORM (shareable content object reference model) package is available to facilitate results and completion tracking on most current learning management systems.
Jaya Ant Lion Optimization-Driven Deep Recurrent Neural Network for Cancer Classification Using Gene Expression Data (Preprint)
Authors: Majji Ramachandro
Published: November 2020

BACKGROUND

Cancer is one of the deadly diseases prevailing worldwide and the patients with cancer are rescued only when the cancer is detected at the very early stage. Early detection of cancer is essential as, in the final stage, the chance of survival is limited. The symptoms of cancers are rigorous and therefore, all the symptoms should be studied properly before the diagnosis.

OBJECTIVE

Propose an automatic prediction system for classifying cancer to malignant or benign.

METHODS

This paper introduces the novel strategy based on the JayaAnt lion optimization-based Deep recurrent neural network (JayaALO-based DeepRNN) for cancer classification. The steps followed in the developed model are data normalization, data transformation, feature dimension detection, and classification. The first step is the data normalization. The goal of data normalization is to eliminate data redundancy and to mitigate the storage of objects in a relational database that maintains the same information in several places. After that, the data transformation is carried out based on log transformation that generates the patterns using more interpretable and helps fulfill the supposition, and to reduce skew. Also, the non-negative matrix factorization is employed for reducing the feature dimension. Finally, the proposed JayaALO-based DeepRNN method effectively classifies cancer-based on the reduced dimension features to produce a satisfactory result.

RESULTS

The proposed JayaALO-based DeepRNN showed improved results with maximal accuracy of 95.97%, the maximal sensitivity of 95.95%, and the maximal specificity of 96.96%.

CONCLUSIONS

The resulted output of the proposed JayaALO-based DeepRNN is used for cancer classification.
Development, Popularization and Application of An Online OvAge Calculator: Qualitative Study Based on the WeChat Mini Program (Preprint)
Authors: Xu Wenwen , Wang Hui , Zhu Zheng , Wang Quan , Jin Jing , Zhao Haiyang , Shao Fang , Ren Qingling
Published: November 2020

BACKGROUND

At present, there are many clinical markers and models to assess ovarian reserve, but none of them are ideal. The number of clinical samples is a key factor limiting the specificity and sensitivity of the markers and models, and traditional methods of subject recruitment are time and vigor. In addition, the model of ovarian reserve assessment for Chinese women need to be further explored.

OBJECTIVE

To explore the possibility of self-reporting for subjects through the WeChat mini program, and provide more data support for further optimization of the OvAge model, and to develop a predictive model of ovarian reserve that is specific to Chinese women.

METHODS

In this paper, with reference to the existing OvAge model, we developed an online OvAge calculator based on the WeChat mini program for data collection, and then applied the generalized linear model theory to obtain a predictive model of ovarian reserve which is in line with the characteristics of Chinese women.

RESULTS

Compared to traditional recruiting methods, the online OvAge calculator is able to collect a large number of samples in a short period of time, which is efficient and convenient. Optimized model of estimated OvAge =exp (3.5254-0.001*PRL-0.0231*AMH). This model showed a high statistical significance for each marker included in the equation. We applied the final equation on diminished ovarian reserve and polycystic ovary syndrome datasets and obtained a mean of predicted ovarian age significantly different from the mean of chronological age in both groups.

CONCLUSIONS

The OvAge calculator based on the WeChat mini program is a novel online subject self-reporting system that can collect many samples in a short period of time, continuously optimize the model and update the mini program version, which is economical, time-saving and efficient., and is worthy of promotion. In addition, the optimized OvAge model is suitable for Chinese women and provides a reference for clinical assessment of ovarian reserve.

CLINICALTRIAL

The study was approved by Chinese Clinical Trial Registry (registration No. ChiCTR2000037522) and Medical ethics committee of Jiangsu Province Hospital of Chinese Medicine (approved No. 2019NL-152-02).
Smartphone applications for the detection of atrial fibrillation in primary care: a review (Preprint)
Authors: Fraser Nicholas
Published: November 2020

BACKGROUND

Smartphone technology continues to advance at a fervid pace. In the field of cardiology, traditional physical tests recommended to detect cardiac arrhythmias may soon be superseded by low-cost, convenient and reliable smartphone apps. We aimed to determine the screening test accuracy of smartphone apps in detecting atrial fibrillation (AF) in patients within primary care.

OBJECTIVE

The aim of this review was to determine the screening test accuracy of smartphone apps in detecting atrial fibrillation (AF) in patients within primary care.

METHODS

Systematically searched MEDLINE, PUBMED, Web of Science, CINAHL and Cochrane Library until 01 February 2019. Articles were screened, and evaluated before relevant data extracted and study quality appraised using the QUADAS-2 tool. The raw test accuracy data was constructed into a 2x2 contingency table and the test accuracy statistics were calculated, and organised in descriptive plots.

RESULTS

Seven cross-sectional studies tested one, or two smartphone apps including the AliveCor 1-lead 30 sec ECG (seven studies; n=16,359), and the Cardiio Rhythm PPG (one study; n=1,012). The prevalence of AF ranged from 1.17%-12.29%, with a mean of 2.65%. The AliveCor 1-lead device reported a sensitivity ranging from 0.92 to 0.99, and specificity from 0.99 to 1.00. Sensitivity and PPV showed the greatest heterogeneity, with results ranging from suboptimal to excellent. The Cardiio Rhythm PPG app recorded a sensitivity of 0.71 (95% CI 0.51-0.87) and specificity of 0.99 (95% CI 0.98-1.00).

CONCLUSIONS

Community screening for AF using smartphone electrocardiography (ECG) or photoplethysmography (PPG) is feasible. Smartphone apps that screen for AF in primary care demonstrate excellent specificity, but suboptimal sensitivity. Further optimisation of detection algorithms, to accommodate the spectrum of disease seen within the community, should be considered before such devices are used as a tool for systematic auto-screening.
The Clinician satisfaction and experience with the use of Teleconsultation during the pandemic of COVID-19: A Cross Sectional Study (Preprint)
Authors: Zahoor Al-Wardha , Khan Zainab , Khan Amna , Qamar Naveed , Farooqui Sumaira , Allana Raheel , Khan Zeeshan
Published: November 2020

BACKGROUND

In the pandemic of COVID-19, the rise in consultation through telemedicine became common as it is the need of time. Due to the sudden change in traditional health care providing systems, the clinician should address its positive and negative experiences.

OBJECTIVE

This study evaluates the clinician’s satisfaction and experience with the use of teleconsultation provided during the pandemic of Novel Coronavirus and their willingness to continue tele-health after the pandemic.

METHODS

This cross-sectional survey was conducted online in the peak pandemic of COVID-19 in Pakistan. The data was collected on Google form questionnaire from 115 health consultants of different disciplines recruited through social media. The questionnaire contains 15 questions regarding clinician’s satisfaction, quality of treatment and intention to continue providing telehealth-services after the pandemic. Descriptive and inferential statistics were obtained by analyzing the data using SPSS software version 20.

RESULTS

One hundred and fifteen consultants, 28 male and 87 females participated in the study in which 62% were found to have an average and 34% at a high level of satisfaction. Kruskal-Wallis test showed a significant difference among different medical specialist in the continuation of telehealth services after the pandemic of COVID-19 (P=.003) and its recommendation to friends and family (P=.02) with high mean rank in endocrinologist and dermatologist.

CONCLUSIONS

Telemedicine can revamp the quality of care being provided through it. To optimize the innovation in technology, it is important to consider the other side of the perspective that belongs to caregivers. A great number of participants reported a good response for continuation in telemedicine services in their daily routine even after the pandemic situation. However, there is an urgent need to find the solution for the difficulties and drawbacks faced by healthcare providers.

CLINICALTRIAL
Mullaney, Thomas S. The Chinese Typewriter: A History. MIT Press, 2017.
Authors: Mercier Edad
Published: November 2020

N/a
A Clinical Case Study on the Developmental Process of Addictive Behaviors from a Psychological Perspective: Proposal of Early Prevention Probability
Authors: Uji Masayo
Published: November 2020

This article aimed at building a comprehensive hypothesis on the origin and developmental process of addictive behaviors based on facts obtained from the author’s clinical experience. A woman with a variety of addictive behaviors was introduced as an instance. Not only childhood adversity which contribution already had been proven in the development of addiction, the author also focused on psycho-social obstruction during adolescence, more specifically, that of constructing peer relationships as well as that of renewing the relationship with parents crucial for passing through the second individuation process (Blos, 1967). Furthermore, how the obstruction related to the adversity during early life was discussed. At the end of the article, reference was made to possible benefits in adulthood brought about by intervening with adolescents who are at high risk of addictive behaviors.
ASGAR (Animasi Software Geogebra Dan Alat Peraga) untuk Mendukung Proses Pembelajaran Matematika di Kelas
Authors: Aripin Usman , Setiawan Wahyu , Hendriana Heris , Masruroh Ani Ainun
Published: November 2020

Perkembangan teknologi mempengaruhi semua aspek kehidupan, begitupun di dunia pendidikan. Tuntutan guru menjadi lebih banyak, selain administrasi yang harus diselesaikan, ditambah dengan keharusan untuk mampu menggunakan teknologi. Salah satu alternatif solusinya adalah dengan menerapkan pelatihan ASGAR yang bertujuan untuk mendukung kegiatan guru-guru dalam pembelajaran matematika. Metode yang digunakan yaitu berupa workshop dan pelatihan secara langsung menggunakan ASGAR kepada guru mulai dari tingkatan SD, SMP dan SMA yang ada di pangalengan. Hasil pelatihannya yaitu pelatihan ASGAR ini mndapat respon positif dari para guru peserta pelatihan.mengetahui bahwa pembelajaran matematika bisa dilakukan dengan menarik sehingga pembelajaran tidak akan terasa membosankan, dan menggunakan media tersebut dalam penyampaian konsep dari suatu materi dengan efisien dan efektif, mengeksplorasi media tersebut sesuai dengan materi yang ingin disampaikan oleh guru.
Program Kreativitas Mahasiswa Kewirausahaan Cheewings
Authors: Kamiliya Eka Putri  , Shazrin Daniyah Khansa  , Rizka Herlina  , Dini Safitri
Published: November 2020

Perkembangan dunia kuliner saat ini menuntut kita untuk berpikir secara kreatif dalam menghasilkan sebuah produk baru oleh sebab itu, inovasi sangat dibutuhkan. Tujuan dari Program Kreativitas Mahasiswa Kewirausahaan cheeWings ini adalah untuk berkontribusi meningkatkan kekreativitasan serta untuk memotivasi masyarakat untuk selalu berinovasi di bidang kewirausahaan agar tetap dapat bersaing di era yang semakin maju ini. Program Kreativitas Mahasiswa ini kami jalankan dengan cara membagikan sepuluh buah produk kepada keluarga dan orang sekitar. Hasil yang kami peroleh cukup baik, mereka berkomentar bahwa produk ini sudah cukup baik dari segi rasa.
PKM Strengthening Organizations through Edupreneurship and the Establishment of a Cooperative for Karang Taruna Balekambang Village - East Jakarta
Authors: Ariwibowo Prasetio , Djuhartono Tjipto
Published: November 2020

This community service activity aims to increase the knowledge and spirit of entrepreneurship (Edupreneurship) for the people of Balekambang - East Jakarta (specifically the Youth Organization management) and the entire Balekambang community - East Jakarta (especially the Youth Organization management) is expected to understand the principles and have a Cooperative in under the auspices of a legal entity foundation and the adoption of technology throughout the Balekambang community - East Jakarta. This training method (PKM) is in the form of entrepreneurship training, business management training (Edupreneurship). Participants (youth organization and community in Balekambang, East Jakarta) participated in this activity with enthusiasm, this was indicated by questions and responses regarding the material provided. During the training activities, in addition to participating as participants, partners played a role in providing training venues, participated in socializing training programs that would be carried out to the youth committee and community members in Balekambang, East Jakarta. So that the participation of partners is very supportive of the overall implementation of the PKM program activities.
Pemeriksaan Golongan Darah dan Rhesus Pada Siswa Kelas X SMA Negeri 11 Bengkulu Utara
Authors: Dian Fita Lestari  , Fatimatuzzahra Fatimatuzzahra , Jarulis Jarulis
Published: November 2020

Golongan darah bersifat herediter dan sangat penting untuk diketahui karena terkait dengan keberhasilan transfusi darah, transplantasi organ, maupun penyakit herediter. Pada sistem golongan darah yang sering digunakan adalah sistem ABO, berdasarkan keberadaan antigen A dan B yang terdapat di permukaan sel darah merah. Serta sistem golongan darah rhesus merupakan terbesar kedua setelah sistem ABO, yang ditentukan berdasarkan keberadaan antigen D. Karena pentingnya mengetahui golongan darah dan rhesus sehingga perlu adanya pemeriksaan golongan darah dan rhesus siswa kelas X di SMA Negeri 11 Bengkulu Utara. Metode yang digunakan dalam kegiatan pengabdian ini meliputi persiapan alat bahan yang digunakan untuk pemeriksaan golongan darah serta pelaksanaan kegiatan sehingga didapatkan hasil golongan darah setiap siswa. Pemeriksaan golongan darah diikuti oleh siswa sebanyak 34 orang, 13 laki-laki dan 21 perempuan. Berdasarkan hasil pemeriksaan, persentase siswa yang memiliki golongan darah A 29,4%, golongan darah B sebanyak 29,4%, golongan darah O sebanyak 29,4%, serta golongan darah AB yang paling sedikit yaitu 11,8%. Berdasarkan hasil pemeriksaan rhesus, menunjukkan bahwa semua siswa memiliki rhesus positif (Rh+).
Penerapan Teknologi Closed system Pada Pembudidaya Udang Vaname (Litopenaeus vannamei) Kelompok “Laut Mina Budidaya” Bireuen, Aceh
Authors: Akmal Yusrizal , Rindhira Humairani  , Mandasari  , Ilham Zulfahmi
Published: November 2020

Desa Lipah Rayeuk merupakan salah satu daerah yang terletak di pesisir Kabupaten Bireuen yang memiliki potensi sumber daya perikanan laut dan payau khususnya tambak udang vaname, namun permasalahan pada tambak udang vaname adalah kurangnya pemahaman pengeloaan kualitas air, masih menggunakan sistem pengelolaan air untuk tambak masih open system, teknologi dan manajemen budidaya udang belum dipahami sehingga menyebabkan produksi setiap panen menurun. Program pengabdian masyarakat dilaksanakan pada  kelompok Laut Mina Budidaya di Desa Lipah Rayeuk, Kabupaten Bireuen. Metode yang digunakan dalam kegiatan ini adalah pendampingan perbaikan teknologi budidaya yang diterapkan adalah closed system yang danaplikasi probiotik pada air. Tahapannya pertama dimulai dari persiapan kolam tandon, kolam pemeliharaan, pengapuran, pemupukan, dan sterilisasi air. Tahapan kedua melakukan penambahan probiotik pada air di tendon penampungan. Hasil kegiatan pengabdian kepada masyarakat peningkatan kepatuhan mitra terhadap SOP pengontrolan kualitas air sudah tinggi, ini merupakan kunci dari keberhasilan usaha budidaya udang vaname. Peningkatan pemahaman mitra tentang pengetahuan dan praktikal aplikasi closed system sebesar 3,53 % sampai dengan 10,91%. Untuk pelaksanaan pengabdian masyarakat berikutnya kegiatan difokuskan untuk membantu mitra dalam proses proses pembutan pakan dengan menerapkan teknologi fermentasi dan pelet dan mengupayakan untuk meningkatkan produksi udang vaname.
Optimalisasi Peran Kader Laktasi Berbasis Lactation Training sebagai Penunjang Keberhasilan ASI
Authors: Nuari Nian Afrian , Kartika Sari Melani , Nur Aini Efa
Published: November 2020

Cakupan pemberian ASI eksklusif di Indonesia masih belum optimal karena beberapa faktor.  Hal ini perlu mendapatkan perhatian akan pentingnya keberhasilan ASI eksklusif  . Tujuan dari kegiatan  ini meningkatkan optimalisasi peran kader laktasi berbasis lactation training sebagai penunjang keberhasilan asi.  Metode dalam pengabdian ini  meliputi pelatihan  peran kader laktasi dan mendemontrasikan cara menyusui yang benar dan mendemonstrasikan cara penggunaan metode breast pump untuk meningkatkan keberhasilan ASI pada ibu yang bekerja.  Kegiatan ini dilakukan dengan melibatkan mitra kader laktasi yang terdiri dari  20 orang.  Dari hasil kegiatan ini terdapat 20 kader laktasi yang mayoritas berusia 40 tahun, berpendidikan SMA, dan pernah mendapatkan informasi tentang keberhasilan ASI eksklusif sebelumnya. Berdasarkan uji T Test terdapat pengaruh tingkat pengetahuan setelah dilakukan lactation training yang mampu menunjang keberhasilan ASI eksklusif. Peran kader laktasi ini diharapkan mampu meningkatkan upaya keberhasilan ASI eksklusif dan mendukung ibu bekerja tetap memberikan asi eksklusif kepada bayinya.
Experimental Comparison of Bohm-like Theories with Different Primary Ontologies
Authors: Pang Arthur O. T. , Ferretti Hugo , Lupu-Gladstein Noah , Tham Weng-Kian , Brodutch Aharon , Bonsma-Fisher Kent , Sipe J. E. , Steinberg Aephraim M.
Published: November 2020

The de Broglie-Bohm theory is a hidden-variable interpretation of quantum mechanics which involves particles moving through space along deterministic trajectories. This theory singles out position as the primary ontological variable. Mathematically, it is possible to construct a similar theory where particles are moving through momentum-space, and momentum is singled out as the primary ontological variable. In this paper, we construct the putative particle trajectories for a two-slit experiment in both the position and momentum-space theories by simulating particle dynamics with coherent light. Using a method for constructing trajectories in the primary and non-primary spaces, we compare the phase-space dynamics offered by the two theories and show that they do not agree. This contradictory behaviour underscores the difficulty of selecting one picture of reality from the infinite number of possibilities offered by Bohm-like theories.
Transformation of civil service employees’ professional development system
Authors:   Russian Presidential Academy of National Economy and Public Administration, EVAROVICH SVETLANA A. , LAVROVA TATYANA B. ,   Russian Presidential Academy of National Economy and Public Administration, POLYAKOVA ALEXANDRA G. ,   Russian Presidential Academy of National Economy and Public Administration
Published: November 2020

Since maintaining and improving the qualification level by the civil servant is implemented through the professional development, the study identifies main changes affecting this area, including those caused by the changes in the legal regulation.
Evaluation of management tools for stimulating the investment climate in Russian regions
Authors:   Russian Presidential Academy of National Economy and Public Administration, KONDRATENKO OLEG I.
Published: November 2020

The influence of management tools on the development of the territorial investment climate is assessed ambiguously by scientists and experts, as evidenced by the literature review conducted in the article. Analysis of thematic works revealed a significant scatter of scientists’ opinions regarding the role of management in the development of the investment climate. The lack of methodological unity significantly complicates the possibility of a comprehensive valid assessment of managerial tools of the regional investment economy. Assuming the possibility of the influence of the managerial factor on the development of the business climate of the Russian regions, the article proposed and tested a comprehensive approach, including, in particular, a survey of investors, entrepreneurs and employees of regional project offices regarding the state of the investment climate management system in the regions. The study showed that the importance of the managerial factor in the regional investment policy of Russia is significant, but it manifests itself most explicitly during large-scale crises and turbulence of the economy. A growing degree of satisfaction with the state of the regional investment climate, as well as an increase in user complaints about the efficiency, speed and quality of functioning of the established management institutions were also revealed. A survey conducted by the author of the staff of the regional project offices made it possible to determine the difficulties of the performers in managing the development of the regional investment climate, namely: insufficiency of material and technical and technological support for the work of design offices; low competence of employees with their functional congestion; lack of involvement in the work of attracting investments of specialized organizations, municipal administrations; different level of regional digitalization.
Miniforums as an effective way to attract investment in small and medium-sized business projects
Authors:   Russian Presidential Academy of National Economy and Public Administration, GAPONENKO ALEXANDER L. , SOBLIROV AZAMAT A. ,   Community ‘Business Angels of Russia’
Published: November 2020

An important factor in the development of small and medium-sized businesses is consulting support that helps to attract investment. According to studies, investment advice prefers to follow a large business, while highly relevant issues of interaction between investors and small and medium-sized business project initiators often remain out of sight. The article reviews and analyzes the best practices for holding mini-forums aimed at creating sustainable links between project initiators in need of investment and private investors willing to invest in highly efficient business projects. This kind of interaction format increases the productivity of consulting activities in the field of helping small and medium-sized business project initiators in finding investments. Holding domestic mini-forums today is concentrated in the framework of the ‘Business Angels of Russia’ Community. Within the framework of mini-forums, investors can get detailed information about several projects at once, and project initiators find their investor faster and easier. Consultants, in turn, expand the range of potential clients. In general, the practice of holding mini-forums contributes to the activation of potential and existing investors and the development of small and medium-sized businesses in Russia.
Macro- and microelements occurence in soil and plant (leaves) samples of a representative and potentially sustainable Mediterranean vineyard
Authors: JIMENEZ-BALLESTA RAIMUNDO , Bravo Sandra , Reyes Caridad Pérez de los , AMOROS JOSE A. , Garcia-Pradas Jesus , Sánchez Monica , GARCIA-NAVARRO FRANCISCO
Published: November 2020

The study reported here concerns the geochemical distributions of macro-
and trace elements (including potentially toxic elements, PTEs) in the
vineyard soils of Alcubillas, which is one of the oldest, albeit not
world-reknowned, wine-growing areas in La Mancha (Central Spain). Soil
and leaf samples were analyzed by X-ray fluorescence spectrometry to
ascertain the levels of various elements in the soil and the plant. The
potential toxicity of the elements was assessed with regard to the
development of the vineyard. Despite the fact that fertilizers and
pesticides are employed in the vineyards in this area, the results
showed that the levels of trace elements in the soil samples did not
exceed the reference values according the pedogeochemical values for the
region and Spain. This finding suggests that the study area is not
polluted. The Biological Absortion Coefficient (BAC) was calculated to
assess the assimilation of various elements from the soil to the leaves,
and differences were found in the element absorption capacity of the
vines. Some elements were not taken up by Vitis vinifera despite
elements like Zr and Rb being present in relatively high concentrations
in the soil. The production in these soils of grapes and wine does not
represent a threat to human health or the ecosystem, because the farmers
in this area are extremely careful to preserve the environment and they
only farm to achieve moderate yields of grapes per hectare.