bluuebunny/crossref_metadata_2025 huggingface dataset:
The Addition Effects of Glucose as a Co-substrate on Xylitol Production by Candida guilliermondii
Authors: Ambarsari Laksmi , Suryani Suryani , Gozales Steffanus , Puspita Puspa Julistia
Published: August 2020

High cost production is one of the constraints of the commercial xylitol production due to high energy needed and pure raw materials. Therefore, it is necessary to improve the xylitol production eficiently with lower production cost by using microorganisms. The research objectives were to determine the optimum xylitol production from xylose by metabolism of C. guilliermondii and effect of glucose as a co-substrate in fermentation medium. The ratio of glucose : xylose (g/L) was 1:25, 1:12, 1:5 and 1:2.5 respectively. The xylitol concentration was measured by spectrophotometer method (D-sorbytol/D-xylitol kit). The result showed that the exponential phase of Candida guilliermondii was 12 h to 36 of incubation and optimum of incubation time to produce the highest xylitol was 72 h. The best ratio- of glucose : xylose to produce xylitol was 9 g/L glucose : 45 g/L xylose (1 : 5). The xylitol concentration produced from medium with the addition of glucose was 2.85 g/L. This concentration increased five times compared to that in the medium without addition of glucose that only reached 2.85 g/L. According to this study, the addition of glucose as a co-substrate could increase the xylitol production.
Isolation and Characterization of Endophytic Bacteria from Tembelekan (Lantana camara L.) as Antibacterial Compounds Producer
Authors: Saputri Dina Dyah , Bintang Maria , Pasaribu Fachriyan H
Published: August 2020

Endophytic bacteria are microorganisms that live in the internal tissues of plants and have symbiotic mutualism with their host plants. Endophytic bacteria may produce secondary metabolites that can be developed for medical, agricultural, and industrial purposes. Lantana camara is a medicinal plant that has therapeutic potential to treat a variety of diseases such as fever, tuberculosis, rheumatism, asthma, and skin disease. The purpose of this study was to isolate and characterize endophytic bacteria from Lantana camara which has potential to produce antibacterial compounds. The method of this research include isolation of endophytic bacteria of Lantana camara. Antibacterial activity assay was done against four types of pathogenic bacteria i.e. Bacillus cereus, Escherichia coli, Staphylococcus aureus, and Salmonella enteritidis. Characterization of endophytic bacteria was by 16S rRNA gene analysis and identification of antibacterial compounds by GC-MS analysis. Isolation of endophytic bacteria from Lantana camara resulted in BT22 as a potential isolate. Analysis of 16S rRNA gene showed that the BT22 isolate was similar to Bacillus amyloliquefaciens YB-1402 with 99% identity. The results of GC-MS analysis showed some antibacterial compounds such as: Cyclohexanone, 2-[2-(1,3-dithiolan-2-yl)propyl]-6-methyl-3-(1-methylethyl), Octadecane (CAS) n-Octadecane and Tetracosane (CAS) n-Tetracosane.
Molecular Interaction Analysis of COX-2 against Curcuminoid and Xanthorizol Ligand as Anti Breast Cancer using Molecular Docking
Authors: Pratama Ridho , Ambarsari Laksmi , Sumaryada Tony Ibnu
Published: August 2020

Breast cancer is one of the most common cancer in the world that occurs in women. Thedevelopment process of cancer is regulated by a variety of pathways that involve various enzymes. COX-2 is an enzyme involved in the inflammatory process in further stages that will play importantroles in breast cancer cells progression. The uses of natural compound from plants give new hope forbreast cancer treatment with minimal side effects. Temulawak is a potential breast cancer drugs because it contains curcuminoid and xanthorizol. Curcumin and xanthorizol has been reported to have chemopreventive effect on colon cancer development. The drug that has same functions of these compounds needed to be examined with various approaches. One of the approach used in this research is molecular docking. Based on ligand analysis with Lipinski and toxicity test using ADMET, curcuminoid and xanthorizol met criteria as medicinal compounds. Curcumin had the highest binding affinity(?G) with the value -9.3 kcal/mol but still under commercial drug celecoxib binding affinity (?G) = -12,5. There were three hydrogen bonds in amino acid Arg106 and Tyr341 His75 which were amino acids in the active side of COX-2. There were 15 amino acids that have similar ties with commercial drug celecoxib. Based on the binding affinity and binding similiarity, curcuminoid and xanthorizol were predicted as compounds that have potential as competitive inhibitor of COX-2 enzyme.
Toxicity Extract and Faction of Surian Toona sinensis Leaf and Bark against Shrimp Larvae Artemia salina L.
Authors: Theresia Rori , Falah Syamsul , Safithri Mega , Assyar Muhammad
Published: August 2020

Surian (Toona sinensis) is one of the herbs that contain many bioactive compounds. Part of surian plants that can be utilized as therapy is leaf and bark. This study aims to determine the toxicity of leaf and bark extract of Surian through Bhrine Shrimp Lethality Test (BSLT), then compare toxic concentration of water extract, and ethanol 70 %, and n-hexane, diethyl ether and ethyl acetate fractions to shrimp larvae (Artemia salina L). The results showed that water content of leaves simplicia was 8.08 % and bark was 6.26 %. The highest extract rendement value by ethanol solvent was 23 %. The result of BSLT test probit analysis showed that the extract of ethyl acetate bark fraction had the highest toxicity with LC50 value 405.641 ppm, while leaf water extract had the lowest toxicity with LC50 value 707.787 ppm.
Antioxidant Status of Sprague-Dawley Female Rat with Curcuminoids Nanoparticles of Balittro Curcuma
Authors: Ambarsari Laksmi , Febrianti Riska , Purwakusumah Edy Djauhari
Published: August 2020

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Quinba R-TC: nueva variedad de jamaica tipo criolla de alto rendimiento
Authors: Ariza Flores Rafael , Gálvez Marroquín Luis Antonio
Published: August 2020

Los cultivadores de jamaica siembran genotipos criollos que se cosechan en el mes de diciembre con rendimientos bajos que promedian de 250 a 300 kg ha-1 en asociación con maíz y de 500 a 600kg ha-1 en unicultivo. Con el propósito de ampliar la oferta de genotipos, aumentar los rendimientos y disminuir las importaciones se ofrece la variedad mejorada Quinba R-TC que conserva el color, sabor y fecha de floración de la criolla regional y se mejoró el tamaño del cáliz, por lo que es una opción para incrementar los rendimientos y la rentabilidad de este cultivo en casi 20 mil hectáreas que se siembran a nivel nacional. Quinba R-TC, es producto de la cruza entre plantas de jamaica tipo Sudán (JTS) colectadas y seleccionadas en 2008 de un lote establecido en la zona jamaiquera del Estado de Guerrero y plantas provenientes de la variedad Tecoanapa conocida como criolla regional (CR). Con la F2 se inició la selección individual purificando en cada ciclo. La línea purificada se obtuvo en F7 y en 2013 se inició su evaluación y caracterización. Los descriptores básicos de selección fueron: uniformidad de la planta, tamaño y color rojo intenso del cáliz y rendimiento, el resultado fue una planta con siete días más precoz, los de cálices de color similar a la criolla regional y con 70% más grandes y de mínima pubescencia. Los rendimientos promedio fueron 80% mayores a la variedad de referencia; por lo tanto, es possible aumentar la producción de 4 500 a 8 000 t año-1.
Productividad del agua y rendimiento de maíz bajo diferente disponibilidad de humedad
Authors: Sánchez Homero Alonso , Robledo Margarita Tadeo , Calderón Alejandro Espinosa , Esparza Job Zaragoza , López Consuelo López
Published: August 2020

La experimentación con híbridos para condiciones con escasez de agua es fundamental para la seguridad hídrica y alimentaria, integrando el manejo de cultivos con el de los recursos hídricos. El objetivo en este trabajo fue definir la productividad del agua, el rendimiento de grano y el peso hectolítrico en tres ambientes con diferente disponibilidad de humedad: riego y temporal en la FESC-UNAM y riego en Texcoco, Estado de México; utilizando cinco híbridos de maíz de la UNAM y cinco del INIFAP, con dos densidades de siembra. Se estableció el experimento en bloques completos al azar y se registraron variables durante el ciclo y a la cosecha; la productividad total del agua se calculó como el volumen total de agua entre el rendimiento de grano a 14% de humedad. Utilizando SAS se realizó el ANOVA para el análisis de los factores y sus interacciones, se separaron las medias con la prueba de Tukey al 5%. Se encontró efecto de la interacción ambiente x híbrido e híbrido x densidad de siembra en la productividad total del agua. En el rendimiento de grano se encontró efecto de la interacción ambiente x híbrido, ambiente x densidad e híbrido x densidad. Se encontró efecto altamente significativo en el peso hectolítrico del ambiente y del tipo de híbrido. La interacción del híbrido Atziri Puma con los ambientes y con la densidad de siembra mostraron los valores máximos de productividad total del agua y del rendimiento de grano.
PENTINGNYA PENCATATAN DALAM MENINGKATKAN KINERJA KEUANGAN BADAN USAHA MILIK DESA (BUMDes) DI DESA BANTENGPUTIH
Authors: Ismiyah Elly
Published: August 2020

Secara geografis Desa Bantengputih adalah salah satu desa yang terletak di wilayah Kecamatan Karanggeneng Kabupaten Lamongan yang mana Desa Bantengputih ini terdapat 3 dusun, yaitu Dusun Koloputih, Dusun Setrobanteng, dan Dusun Bekanang. Sebagian besar masyarakatnya mempunyai ladang yang cukup luas untuk bertani padi. Desa Bantengputih memilki Badan Usaha Milik Desa (BUMDes) yang di nantinya akan menambah pendapatan desa. Badan Usaha Milik Desa (BUMDes) yang ada di desa Bantengputih mempunyai tujuan untuk menyejahterakan masyarakat di desa Bantengputih dengan memberikan modal kepada petani yang nantinya akan di gunakan sebagai modal untuk mengolah lahan pertanian dan juga memberikan modal untuk para pelaku usaha mikro. Oleh karena itu, untuk mengatur kegiatan administrasi keuangannya Badan Usaha Milik Desa (BUMDes) harus melakukan pencatatan dan pembukuan yang baik dan benar dengan membagikan pembukuan sederhana seperti buku kas dan buku pembantu utang untuk nantinya mempermudah pecatatan yang dilaksanakan pada tanggal 16 Agustus 2019. Kegaiatan ini dilakukan dengan metode sosialisai kepada para pengurus Badan Usaha Milik Desa (BUMDes) dengan tujuan untuk meningkatkan kinerja keuangan dari Badan Usaha Milik Desa (BUMDes).
PEMASANGAN SENSOR CAHAYA OTOMATIS UNTUK PENERANGAN JALAN UMUM DI DESA KARANGSEMANDING
Authors: Syaiful Syaiful
Published: August 2020

Sensor cahaya adalah komponen elektronika yang dapat memberikan perubahan besaran elektrik pada saat terjadi perubahan intensitas cahaya yang diterima oleh sensor cahaya tersebut. Sensor cahaya dalam kehidupan sehari-hari dapat kita temui pada penerima remote televisi dan pada lampu penerangan jalan otomatis. Sensor cahaya tipe fotokonduktif akan memberikan perubahan resistansi pada terminal outputnya sesuai dengan perubahan intensitas cahaya yang diterimanya. Sensor cahaya tipe fotovoltaik ini ada beberapa jenis diantaranya adalah LDR (Light Depending Resistor), Photo Transistor dan Photo Dioda. LDR adalah sensor cahaya yang memiliki 2 terminal output, dimana kedua terminal output tersebut memiliki resistansi yang dapat berubah sesuai dengan intensitas cahaya yang diterimanya. Photo transistor adalah suatu transistor yang memiliki resistansi antara kaki kolektor dan emitor dapat berubah sesuai intensitas cahaya yang diterimanya. Photo transistormemiliki 2 terminal output dengan nama emitor dan colektor, dimana nilai resistansi emeitor dan kolektro tersebut akan semakin rendah apabila intensitas cahaya yang diterim photo transistor semnakin tinggi. Photo dioda adalah suatu dioda yang akan mengalami perubahan resistansi pada terminal anoda dan katoda apabila terken cahaya. Nilai resistansi anoda dan katoda pada photo dioda akan semakin rendah apabila intensitas cahaya yang diterima photodioda semakin tinggi.
Sulla centralità di spazio e territorio nel progetto di rigenerazione delle montagne e delle aree interne
Authors: De Rossi Antonio , Mascino Laura
Published: August 2020

The crisis brought on by Covid-19 has dramatically highlighted how the territorial dimension has long been excluded from national policies to be reduced to a mere diagrammatic and abstract space to be reduced in a mere diagrammatic and abstract space. An unphysicality of things that also goes through philosophies of smart or replicable best practices, in the idea that it is enough to follow a procedure to solve the complexities of contemporary life.
The crisis has also brought to light the theme of internal, mountain and marginal areas, which have already received strong and growing attention in recent years.
All the researches of the last few years demonstrate how the frontier of innovation is placed along the margin lines, in territories such as the Alpine and Apennine ones: regeneration projects based on culture, community cooperatives, resettlement that arises on the recovery of legacy and on the new technologies. These are experiments as fragile as the places they insist on, but where the territorial and spatial dimension plays an active and new role, which should be carefully observed thanks to the new openings it can offer.
The essay identifies some nodes that arise from a long process of analysis and field experiences, and which intertwine two strategic issues: on the one hand, the need for policies capable of actively addressing the issue of territories – overcoming the contrast between socio-economic and spatial disciplines –, and on the other hand the project of reactivation and regeneration of mountain and marginal spaces.
Sobre performance e historicidade: uma abordagem estética e cultural da MTV Brasil
Authors: Gutmann Juliana Freire
Published: August 2020

O artigo apresenta uma proposta de articulação conceitual para a apreensão, numa perspectiva histórica, do desempenho da MTV Brasil, seus modos de fazer, de se relacionar com a audiência e contextos culturais, processo aqui traduzido pela ideia de performance televisiva. Examina a emissora enquanto uma ambiência de experiência televisual, constituída por um contínuo processo de disputas por valores e sentidos, por continuidades e rupturas materializadas em seus programas e nos modos de convocação de marcas de gênero (televisivos e musicais). Projeta-se aqui uma expectativa mais ampla de pesquisa: discutir procedimentos para a análise de uma organização midiática, pela articulação entre os conceitos de gênero, performance e estrutura de sentimento, como possibilidade de promover diálogo entre a estética e os estudos culturais
Teoria das mediações sociais: refinamento ou obsolescência?
Authors: Maio Ana Maria Dantas de
Published: August 2020

O artigo propõe um mergulho nas origens e concepções recentes da teoria das mediações sociais, proporcionando reflexões a respeito de sua aplicabilidade. Aponta fragilidades metodológicas e resgata críticas conceituais fundamentadas no afastamento da teoria do campo da comunicação. Relaciona pesquisas atuais sobre as mediações ao conceito de midiatização, tendência seguida por pesquisadores brasileiros e estrangeiros. Por meio da pesquisa bibliográfica, conclui que a teoria está em permanente construção e potencialmente consegue responder a alguns questionamentos comunicacionais.
As sedutoras da camiseta: mito, conflito e imaginário em jogo
Authors: De Siqueira Euler David , Siqueira Denise da Costa Oliveira
Published: August 2020

O objetivo deste artigo é investigar a produção de sentidos sobre o corpo feminino a partir de um imaginário de gênero posto em evidência por meios de comunicação. Partindo de um referencial teórico que inclui Durand, Wunenberger e Breton, fazemos uma leitura da polêmica desencadeada pelo lançamento de produtos referentes à Copa do Mundo realizada no Brasil contendo imagens de caráter ambíguo sobre a mulher brasileira. A questão teve destaque na imprensa internacional instaurando um campo polifônico e polissêmico repleto de tensão. Metodologicamente, esta é uma pesquisa de natureza qualitativa orientada pelos princípios da sociologia compreensiva. Por meio de pesquisa documental de material midiático, assim como da leitura das falas, relacionamos mitos, imaginários e conflitos tendo em vista sua oposição e complementaridade. Finalmente, fazendo uso da distinção entre problema social e problema sociológico, buscamos compreender a situação em termos de interação social.
A Saúde da Nossa Gente: a popularização da ciência nos veios da educação não formal
Authors: Oliveira Antonio José Silva , De Araújo Ana Lourdes Alves
Published: August 2020

Este artigo é resultado do trabalho desenvolvido no grupo de Pesquisa Cultura Científica e Produção de Conhecimentos Educacionais, do Programa de Pós-Graduação em Educação da Universidade Federal do Maranhão, que centra sua investigação na divulgação científica, popularização da ciência ou compreensão pública da ciência, termos usados neste trabalho com o mesmo sentido, a fim de buscar aproximações entre as ações de divulgar e educar. Para tanto, utilizou-se a História Oral como metodologia, uma vez que por esse aspecto da pesquisa qualitativa é possível explorar as relações entre história e memória, que se constitui na essência desta pesquisa. A construção da história e memória dos programas Alimentação é Vida e A Saúde da Nossa Gente veiculados na Rádio Educadora Rural do Maranhão, nas décadas de 1980 e 1990 foram realizadas por meio do diálogo com as fontes coletadas: narrativas das pessoas, gravações em fitas dos programas, entre outras, sob o veio teórico da Educação Popular de Paulo Freire e de estudiosos da educação não-formal, como Maria da Gloria Ghon, possibilitaram constatar que esses programas radiofônicos constituíram-se importantes instrumentos de educação não-formal, pelo fato de tornarem dinâmicas as ações que tratavam o conhecimento científico como prática social, permitindo que, por um curto espaço de tempo, a ciência fizesse parte do cotidiano das pessoas da periferia e da comunidade rural do Maranhão.
Vốn tâm lý và tính cách cá nhân tác động đến sự gắn kết của nhân viên khách sạn tại TPHCM
Authors: Giao Ha Nam Khanh , Anh Huynh Diep Tram , Ngan Nguyen Thi Kim , Dong Doan Quang , Phuc Nguyen Pham Hanh , Vuong Bui Nhat
Published: August 2020

Nghiên cứu nhằm xác định sự ảnh hưởng của vốn tâm lý, tính cách cá nhân đến sự gắn kết công việc của nhân viên khách sạn tại Thành phố Hồ Chí Minh (TPHCM) bằng việc khảo sát 378 nhân viên hiện đang làm việc tại các khách sạn từ 3 sao trở lên, trên địa bàn TPHCM. Các phương pháp thống kê mô tả, phân tích nhân tố khám phá, phân tích hồi quy được sử dụng với sự hỗ trợ của phần mềm SPSS 20. Kết quả cho thấy cả 4 yếu tố thuộc vốn tâm lý: sự hy vọng, sự tự tin, khả năng thích ứng và tính lạc quan đều có tác động cùng chiều đến sự gắn kết công việc của các nhân viên khách sạn. Bên cạnh đó, nghiên cứu cũng đưa ra sự tác động của các yếu tố thuộc tính cách cá nhân đến sự gắn kết trong công việc của nhân viên. Nghiên cứu cũng đề xuất một số hàm ý quản trị mà nhà quản trị có thể vận dụng trong ứng xử về vốn tâm lý, tính cách cá nhân nhằm nâng cao sự gắn kết trong công việc của nhân viên khách sạn tại TPHCM.
Experimental Epistemology and "Gettier" Cases
Authors: Turri John
Published: August 2020

This chapter reviews some faults of the theoretical literature and findings from the experimental literature on “Gettier” cases. Some “Gettier” cases are so poorly constructed that they are unsuitable for serious study. Some longstanding assumptions about how people tend to judge “Gettier” cases are false. Some “Gettier” cases are judged similarly to paradigmatic ignorance, whereas others are judged similarly to paradigmatic knowledge, rendering it a theoretically useless category. Experimental procedures can affect how people judge “Gettier” cases. Some important central tendencies in judging “Gettier” cases appear to be robust against demographic variation in biological sex, age, language, and culture, although there could be some interesting differences related to culture and personality traits. Some remaining questions regarding Gettier’s cases, “Gettier” cases, and “the Gettier problem” concern the psychology and sociology of contemporary anglophone theoretical epistemology. Some remaining questions regarding the empirical study of knowledge judgments concern mechanisms underlying observed behavioral patterns.
Tháng 8-2020, ISR với Nature, RePEc và Springer
Authors: Ho Manh-Toan
Published: August 2020

ISR | Phenikaa Uni (URL: https://isr.phenikaa-uni.edu.vn/chitiet/tin- tuc_2019_2_22_7_58_84/thang-8-2020-isr-voi-nature-repec-va-springer) — COVID-19 bùng phát lần 2 đang gây lo lắng ở Việt Nam. Ảnh hưởng tiêu cực của dịch bệnh có thể cảm nhận được rất rõ trong công việc. Ngoài cản trở và đình trệ với sản xuất, công việc biên tập bình duyệt cũng bị tồn đọng, dẫn đến chờ đợi kéo dài. Tỷ lệ từ chối cũng có khuynh hướng tăng vọt.
Assessing the reliability of an online behavioural laterality battery: A pre-registered study.
Authors: Parker Adam James , Woodhead Zoe Victoria Joan , Thompson Paul Andrew , Bishop Dorothy Vera Margaret
Published: August 2020

Studies of cerebral lateralisation often involve participants completing a series of perceptual tasks under laboratory conditions. This has constrained the number of participants recruited in such studies. Online testing can allow for much larger sample sizes but limits the amount of experimental control that is feasible. Here we considered whether online testing could give valid and reliable results on four tasks: a rhyme decision visual half-field task, a dichotic listening task, a chimeric faces task, and a finger tapping task. We recruited 392 participants, oversampling left-handers, who completed the battery twice. Three of the tasks showed evidence of both validity and reliability, insofar as they showed hemispheric advantages in the expected direction and test-retest reliability of at least r= .75. The reliability of the rhyme decision task was less satisfactory (r= .62). We also confirmed a prediction that extreme left-handers were more likely to depart from typical lateralisation. Lateralisation across the two language tasks (dichotic listening and rhyme judgement) was weakly correlated, but unrelated to lateralisation on the chimeric faces task. We conclude that three of the tasks, dichotic listening, chimeric faces and finger tapping, show considerable promise for online evaluation of cerebral lateralisation.
Klein Gordon Field in FLRW Space-Time
Authors: Sharma S.K. , Dhungel P.R. , Khanal U.
Published: August 2020

As a continuation of solving the equations governing the perturbation of the Friedmann-Lemaitre-Robertson- Walker (FLRW) space-time in Newman-Penrose formalism, the behaviour of the massive Klein-Gordon (KG) field coupled to the FLRW has been investigated. The Equation of Motion has been written and solved separately for radial and temporal parts. The former solution has come to be in terms of the Gegenbauer polynomials and spherical harmonics and the latter being in the WKB approximation. The particle current, energy momentum tensor and potential have also been obtained.
Identification of Asbestos Content in Bulk Materials Imported in Nepal
Authors: Pathak Arvind , Giri Manbir , Pokhrel Bishnu , Wagle Manoj Nidhi
Published: August 2020

The bulk materials include the construction materials such as plaster sand gravel and cement as well as raw materials. Asbestos is the naturally occurring magnesium silicate mineral fibers which has high tensile strength, flexibility and resistance to chemicals, high temperature and stress; this is why it has been considered and used in bulk materials. These mineral fibers are needle shaped and can stick to lung tissue when inhaled and cause inflammation and serious health problems such as asbestosis, mesothelioma and lung cancer or internal fibrosis. It can be detected by simple microscopic method using mineral acid and heat treatment. The method would help in quality analysis of asbestos fiber and save from asbestos induced disease and to develop alternative materials of asbestos fiber material.
A new species of the genus Cymatopus (Diptera: Dolichopodidae) from Madagascar
Authors: Grichanov I.Ya.
Published: August 2020

A new species Cymatopus madagascarensis is described from Madagascar. It belongs to the C. tibialis group of species, being remarkably similar to Oriental C. thaicus Grootaert et Meuffels, 2001, and differs mainly in the morphology of the male fore tarsus.
Cerebral venous thrombosis in traumatic brain injury: a cause of secondary insults and added mortality
Authors: Netteland Dag Ferner , Mejlænder-Evjensvold Magnus , Skaga Nils O. , Sandset Else Charlotte , Aarhus Mads , Helseth Eirik
Published: August 2020

OBJECTIVE

Cerebral venous thrombosis (CVT) is increasingly recognized in traumatic brain injury (TBI), but its complications and effect on outcome remain undetermined. In this study, the authors characterize the complications and outcome effect of CVT in TBI patients.

METHODS

In a retrospective, case-control study of patients included in the Oslo University Hospital trauma registry and radiology registry from 2008 to 2014, the authors identified TBI patients with CVT (cases) and without CVT (controls). The groups were matched regarding Abbreviated Injury Scale 1990, update 1998 (AIS’98) head region severity score 3–6. Cases were identified by AIS’98 or ICD-10 code for CVT and CT or MR venography findings confirmed to be positive for CVT, whereas controls had no AIS’98 or ICD-10 code for CVT and CT venography or MR venography findings confirmed to be negative for CVT. All images were reviewed by a neuroradiologist. Rates of complications due to CVT were recorded, and mortality was assessed both unadjusted and in a multivariable logistic regression analysis adjusting for initial Glasgow Coma Scale score, Rotterdam CT score, and Injury Severity Score. Complications and mortality were also assessed in prespecified subgroup analysis according to CVT location and degree of occlusion from CVT. Lastly, mortality was assessed in an exploratory subgroup analysis according to the presence of complications from CVT.

RESULTS

The CVT group (73 patients) and control group (120 patients) were well matched regarding baseline characteristics. In the CVT group, 18% developed venous infarction, 11% developed intracerebral hemorrhage, and 19% developed edema, all representing complications secondary to CVT. Unadjusted 30-day mortality was 16% in the CVT group and 4% in the no-CVT group (p = 0.004); however, the difference was no longer significant in the adjusted analysis (OR 2.24, 95% CI 0.63–8.03; p = 0.215). Subgroup analysis by CVT location showed an association between CVT location and rate of complications and an unadjusted 30-day mortality of 50% for midline or bilateral CVT and 8% for unilateral CVT compared with 4% for no CVT (p < 0.001). The adjusted analysis showed a significantly higher mortality in the midline/bilateral CVT group than in the no-CVT group (OR 8.41, 95% CI 1.56–45.25; p = 0.032).

CONCLUSIONS

There is a significant rate of complications from CVT in TBI patients, leading to secondary brain insults. The rate of complications is dependent on the anatomical location of the CVT, and midline and bilateral CVT is associated with an increased 30-day mortality in TBI patients.
Gamma Knife central lateral thalamotomy for the treatment of neuropathic pain
Authors: Franzini Andrea , Attuati Luca , Zaed Ismail , Moosa Shayan , Stravato Antonella , Navarria Pierina , Picozzi Piero
Published: August 2020

OBJECTIVE

The goal of this study was to assess the safety and efficacy of stereotactic central lateral thalamotomy with Gamma Knife radiosurgery in patients with neuropathic pain.

METHODS

Clinical and radiosurgical data were prospectively collected and analyzed in patients with neuropathic pain who underwent Gamma Knife central lateral thalamotomy. The safety and efficacy of the lesioning procedure were evaluated by neurological examination and standardized scales for pain intensity and health-related quality of life. Visual analog scale (VAS) for pain, McGill Pain Questionnaire (MPQ), EuroQol–5 dimensions (EQ-5D), and the 36-Item Short Form Health Survey, version 2 (SF-36v2) were measured during baseline and postoperative follow-up evaluations at 3, 6, 12, 24, and 36 months.

RESULTS

Eight patients with neuropathic pain underwent Gamma Knife central lateral thalamotomy. Four patients suffered from trigeminal deafferentation pain, 2 from brachial plexus injury, 1 from central poststroke facial neuropathic pain, and 1 from postherpetic neuralgia. No lesioning-related adverse effect was recorded during the follow-up periods. All patients had pain reduction following thalamotomy. The mean follow-up time was 24 months. At the last follow-up visits, 5 patients reported ≥ 50% VAS pain reduction. The overall mean VAS pain score was 9.4 (range 8–10) before radiosurgery. After 1 year, the mean VAS pain score decreased significantly, from 9.4 (range 8–10) to 5.5 (mean −41.33%, p = 0.01). MPQ scores significantly decreased (mean −22.18%, p = 0.014). Statistically significant improvements of the SF-36v2 quality of life survey (mean +48.16%, p = 0.012) and EQ-5D (+45.16%, p = 0.012) were observed. At 2 years after radiosurgery, the VAS pain score remained significantly reduced to a mean value of 5.5 (p = 0.027). Statistically significant improvements were also observed for the MPQ (mean −16.05%, p = 0.034); the EQ-5D (mean +35.48%, p = 0.028); and the SF-36v2 (mean +35.84%, p = 0.043). At the last follow-up visits, pain had recurred in 2 patients, who were suffering from central poststroke neuropathic pain and brachial plexus injury, respectively.

CONCLUSIONS

Safe, nonpharmacological therapies are imperative for the management of refectory chronic pain conditions. The present series demonstrates that Gamma Knife central lateral thalamotomy is safe and potentially effective in the long term for relieving chronic neuropathic pain refractory to pharmacotherapy and for restoring quality of life.
How do high preoperative pain scores impact the clinical course and outcomes for patients undergoing lumbar microdiscectomy?
Authors: Virk Sohrab , Vaishnav Avani S. , Mok Jung Kee , McAnany Steven , Iyer Sravisht , Albert Todd J. , Gang Catherine Himo , Qureshi Sheeraz A.
Published: August 2020

OBJECTIVE

Preoperative pain assessment is often used to gauge the amount of disability in patients with lumbar disc herniation. How high preoperative pain scores impact the clinical course and outcomes of patients after lumbar microdiscectomy is not always clear. Here, the authors aimed to determine whether patients reporting higher preoperative pain scores have worse outcomes after lumbar microdiscectomy than those reporting lower preoperative scores.

METHODS

The authors performed a retrospective review of patients with symptomatic lumbar disc herniations that had failed to improve with nonsurgical methods and who had undergone tubular lumbar microdiscectomy. Health-related quality of life (HRQOL) scores had been collected in the preoperative and postoperative period. The anatomical severity of disease was graded based on lumbar disc health (Pfirrmann classification), facet degeneration, thecal sac cross-sectional area, and disc herniation grade. Data on each patient’s narcotic consumption and length of stay were collected. A Student t-test and chi-square test were used to compare patients with high preoperative pain scores (HP cohort) and those with lower preoperative scores (non-HP cohort).

RESULTS

One hundred thirty-eight patients were included in this analysis. The 47 patients in the HP cohort had taken more preoperative opioids (12.0 ± 21.2 vs 3.6 ± 11.1 morphine equivalent doses, p = 0.01). However, there was no statistically significant difference in Pfirrmann classification (p > 0.15), facet grade (p > 0.11), thecal sac cross-sectional area (p = 0.45), or disc herniation grade (p = 0.39) between the HP and non-HP cohorts. The latter cohort had statistically significant higher preoperative PROMIS scores (36.5 ± 7.0 vs 29.9 ± 6.4, p < 0.001), SF-12 mental component summary scores (48.7 ± 11.5 vs 38.9 ± 16.1, p < 0.001), and SF-12 physical component summary scores (PCS; 32.4 ± 8.6 vs 27.5 ± 10.0, p = 0.005), but a lower Oswestry Disability Index (56.4 ± 22.1 vs 35.4 ± 15.5, p < 0.001). There were only two time points after microdiscectomy when the HP cohort had worse HRQOL scores: at the 2-week follow-up for SF-12 PCS scores (32.4 ± 8.6 vs 29.3 ± 7.1, p = 0.03) and the 12-week follow-up for PROMIS scores (45.2 ± 9.5 vs 39.5 ± 7.1, p = 0.01). All other postoperative HRQOL measurements were similar between the two cohorts (p > 0.05).

CONCLUSIONS

A patient’s perceived severity of disease often does not correlate with the actual clinical pathology on imaging. Although patients who report high pain and have a symptomatic lumbar disc herniation may describe their pain as more extreme, they should be counseled that the outcomes of microdiscectomy are positive.
PENGARUH METODE PEMBELAJARAN MIND MAPPING DENGAN MOTIVASI BELAJAR TERHADAP KEMAMPUAN MENULIS TEKS LAPORAN INVESTIGASI SISWA KELAS VI SD YAYASAN IBA PALEMBANG
Authors: Holiyani Holiyani
Published: August 2020

Tujuan penelitian ini untuk mengetahui pengaruh metode pembelajaran mind mapping terhadap kemampuan menulis teks laporan investigasi pada siswa yang memiliki motivasi belajar tinggi dan rendah. Metode penelitian ini adalah metode eksperimen faktorial 2x2. Populasi penelitian adalah siswa kelas VI berjumlah 132 orang yang menjadi sampel sebanyak 32 sebagai kelas eksperimen dan 32 sebagai kelas kontrol dengan teknik penarikan sampel two stage cluster sampling. Teknik pengumpulan data angket dan tes. Teknik analisis yang digunakan adalah uji t dan Anava dua jalur. Hasil penelitian ini dapat disimpulkan bahwa terdapat pengaruh metode pembelajaran mind mapping terhadap kemampuan menulis teks laporan investigasi, terdapat perbedaan kemampuan menulis teks laporan investigasi pada siswa yang memiliki motivasi belajar tinggi dan rendah antara siswa yang diajarkan menggunakan metode pembelajaran mind mapping dengan pembelajaran konvensional, dan terdapat pengaruh interaksi antara metode pembelajaran dan motivasi belajar terhadap kemampuan menulis teks laporan investigasi siswa kelas VI SD Yayasan IBA Palembang.
Analisis Novel Senja di Mata Bintang Karya Dhea Chandra (Kajian Stilistika)
Authors: Susanti Susi
Published: August 2020

Penelitian ini bertujuan untuk mendeskripsikan pemilihan dan penggunaan kosa kata , gaya bahasa, dan keterkaitan sastra dan stilistika dalam novel senja di Mata Bintang Karya Dhea Chandra. Metode yang digunakan ialah metode deskriptif kualitatif digunakan untuk mengolah karakteristik data yang berkaitan dengan analisis, dan menyajikan data yang menarik, dan mudah dibaca. Data berupa dokumen digolongkan sebagai data kualitatif. Berdasarkan hasil analisis isi dokumen di dapatkan keunikan atau kekhasan pemakaian bahasa pada novel Senja di Mata Bintang karya Â Dhea Chandra dilatarbelakangi oleh faktor sosial budaya dan pendidikan penulis yang diungkapkan melalui deskripsi ceritanya Melalui analisis novel ini, diharapkan mahasiswa dapat melakukan kegiatan ekspresi sastra dengan mengungkapkan gaya pengarang dalam menulis sebuah novel, serta mengungkap ruang lingkup yang menjadi latar belakang pengarang menggunakan gaya tertentu dalam menciptakan hasil tulisan yang cukup populer di masyarakat pencinta karya novel
Model of developing students' subject activity in teaching geography
Authors: Belovolova Elena A.
Published: August 2020

The relevance of the article is due to systemic changes in the design and organization of schoolchildren’s activities in teaching geography. In accordance with the requirements of the Federal state educational system, basic General geographical education needs to expand the activity potential, which can be provided by implementing a modern model for the development of students ‘ subject activities. The article reveals the main components of the model, which is formed by the target, theoretical and methodological, content, procedural, evaluative and effective blocks. The article reflects some results of the experimental part of the research, including on the basis of scientific and educational platforms of the Department of methods of teaching geography of the Moscow Pedagogical State University.
A STUDY TO COMPARE THE EFFICACY, FEASIBILITY AND DURABILITY OF CONSERVATIVE & PHYSICAL THERAPY, CORTICOSTEROID THERAPY AND PLATELET RICH PLASMA THERAPY IN PATIENTS SUFFERING FROM DE QUERVAIN’S TENOSYNOVITIS: A PROSPECTIVE COHORT STUDY
Authors: Debasish Deb  , Yumnam Nandabir Singh  , Naorem Bimol Singh  , Rakesh Das
Published: August 2020

Background: de Quervain’s stenosing tenosynovitis (dQSTS) is a tenosynovial disorder which is characterized by impaired gliding of the tendons of the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) muscles over the tendon sheath covering these tendons. The most sensitive clinical test to diagnose dQSTS is Finkelstein's manoeuvre. The management of the disease differs based on the severity of the condition.

Objectives: To prospectively review and compare the efficacy, feasibility and durability of conservative & physical therapy, corticosteroid therapy and platelet rich plasma therapy in the view of (1) symptomatic pain relief, (2) improved the visual analogue scale (VAS) score and functional Mayo’s wrist scores, (3) durability of treatment given and (4) alleviation of need of surgery in patients with de Quervain’s tenosynovitis.

Materials and Methods: After screening of cases, 217 cases entered into the study and the cases were randomized into three groups according to our study protocol. Group a cases were treated with conservative & physical therapy, Group B cases were treated with corticosteroid therapy and Group C cases were treated with autologous platelet rich plasma injection with due pre and post procedural care. The cases were followed up on day 0, at the end of 1st week, 1st and 6th month for pain and range of movements. The patients were followed up for complications and the data were analysed statistically.

Results: A total of 25 (30.06%) cases in group A, 48 (69.56%) cases in group B and 64 (95.52%) cases in group C had recovered from disease at the end of 2nd dose of treatment. At the end of 6th month follow up, a total of 39 (60.93%) cases in group A, 21 (30.43%) cases in group B and 3 (4.47%) cases in group C had recurrence. All these patients were followed up for 1 year which showed a statistical difference with P value of <0.001 in VAS score and 0.001 in Mayo’s wrist scores among all three groups. No adverse reactions and serious complications are noted in the study participants.

Conclusion: Percutaneous needling with autologous PRP injection is the superior modality for de Quervain’s tenosynovitis which minimise the pain and improve the functional quality of life.

Keywords: Platelet rich plasma; de Quervain's stenosing tenosynovitis; Corticosteroid; Percutaneous needling
O2O混合教学模式中塑造高职学生工匠精神研究---以《连锁经营管理》为例
Authors: 刘 娇 , 杨 敬江
Published: August 2020

O2O混合教学模式中《连锁经营管理》课程的工匠精神培养，具有内容多样、形式灵活等特点。文章分别阐述了工匠精神在O2O混合教学模式中融入的意义、工匠精神融入教学设计、工匠精神融入教学资源、工匠精神融入课堂教学、以及工匠精神融入评价体系等内容，为工匠精神融入高职O2O混合教学模式提供了具体的思路和方法，以期促进高职院校的课堂教学改革，提升学生的职业能力和职业素养。
中国优秀传统文化在大学生思想政治教育中的价值及其实现
Authors: 王 刚 , 明 宗超 , 曹 明
Published: August 2020

高校作为传承和发扬中国优秀传统文化的主要阵地，更需要把握好传统文化的基本内涵和特点，在教学过程中渗透中国优秀传统文化，更好实现传统文化教育。本文在分析传统文化基本内涵与特点的基础上，就中国优秀传统文化在大学生思想政治教育中的价值体现和实现路径进行分析，以期更好继承和发扬中国优秀传统文化，构建一个高效的大学生思想政治教育课堂。
00后大学生手机媒介依赖现状及对策分析
Authors: 崔 楠
Published: August 2020

随着移动互联网技术的快速发展，手机媒介已成为00后大学生不可缺少的设备。但是，00后大学生身心发展不成熟，他们在享受手机媒介带来便利的同时，学习求知、社会认知和社会交往也受到了严重的影响，这与新时代本科教育思想中“学生回归刻苦读书学习”是背道而驰的。本文采用问卷调查方法，研究00后大学生对手机媒介依赖的现状及原因，提出可行的干预措施，以引导他们养成正确使用手机媒介的习惯，这也是新时代本科教育思想的践行要求。
A temática indígena nos livros didáticos de Sociologia
Authors: Araújo Ellen Fernanda
Published: August 2020

O presente artigo apresenta uma análise do tratamento da temática indígena em dois livros didáticos da disciplina de Sociologia do Ensino Médio, incluídos nas avaliações do Programa Nacional do Livro Didático dos triênios 2015/2017 e 2018/2020. Trata-se das obras Sociologia Hoje e Sociologia para jovens do século XXI. A escolha por analisar essas duas obras em específico deve-se ao fato de serem aquelas que contém maior volume de referências a temática indígena em suas páginas, em relação às demais constantes no PNLD. O objetivo do trabalho é apresentar a maneira como a temática indígena se articula aos conceitos e teorias das Ciências Sociais presentes no currículo mínimo da disciplina de Sociologia, conforme orientações e parâmetros curriculares estabelecidos pelo Ministério da Educação e diferentes maneira de fazer tal abordagem.
A primeira semana da Consciência Negra do CAP-UERJ sob a ótica da participação de licenciandas/os em Ciências Sociais da UERJ
Authors: Ferreira Walace , Mello Aymara Montezuma , Garcia Daniela Freitas , Souza Charles Rodrigo Alves , Vieira Marcos Antônio , Campagnucci Sebastião Almeida
Published: August 2020

A 1ª Semana da Consciência Negra (SCN) do Instituto de Aplicação Fernando Rodrigues da Silveira (CAp-UERJ) ocorreu no dia 23 de novembro de 2019 em homenagem a intelectual, política e professora negra Lélia Gonzalez. A iniciativa, organizada pelo Departamento de Ciências Humanas e Filosofia (DCHF), contou com a participação da comunidade escolar e de convidados externos. O presente artigo é resultado de ações desenvolvidas pelas/os estudantes e pelo docente da disciplina Estágio Supervisionado III do curso de licenciatura em Ciências Sociais da Universidade do Estado do Rio de Janeiro (UERJ), ocorrida no segundo semestre de 2019, no que se refere à participação de todas/os na 1ª SCN. Nosso objetivo consiste no relato de observações do evento, assim como nas reflexões oriundas de experiências de ensino-aprendizagem obtidas durante esta disciplina de Estágio, quando aproveitamos a 1ª SCN para que licenciandas e licenciandos tivessem uma experimentação prática de elaboração, aplicação e avaliação de uma atividade sociológica e ao mesmo tempo com diálogo interdisciplinar. Ao longo do dia do evento, estivemos frente à apresentação de trabalhos sobre personalidades negras e aspectos da cultura afro-brasileira que nos ajudaram a refletir sobre o lugar do negro na sociedade brasileira, articulando nossas observações junto a conceitos e teorias sociológicas estudadas tanto durante o Estágio Supervisionado III quanto nas aulas de Sociologia no ensino médio do CAp-UERJ.
Relato de experiência a partir do PIBID: Ensino de Sociologia e a Lei 11.645
Authors: Lima Victor Romero
Published: August 2020

O presente trabalho é fruto de um relato de experiência sobre as experiências vivenciadas no Colégio Estadual Professor Ernesto Faria (CEPEF) através do Programa Institucional de Bolsas de Iniciação à Docência (PIBID), com duração de 18 meses, entre Agosto de 2018 e Janeiro de 2020. O objetivo do PIBID é aproximar o licenciandos da escola no universo da licenciatura articulando a prática com a teoria. Durante os dezoitos meses os pibidianos realizaram oficinas, eventos e aulas juntamente com a supervisora da equipe, além de adquirir experiência na área de pesquisa através da observação e aplicação de um formulário. Nesse artigo, apresento uma análise das atividades realizadas com as turmas de primeiro ano do Ensino Médio sobre cultura e identidade afro-brasileira, tendo em vista o cumprimento da lei 11.645/2008.
O ensino de humanidades nas escolas
Authors: Souza Maciana de Freitas , Raposa Patrícia Lorena
Published: August 2020

BODART, Cristiano das Neves (Org.). O ensino de Humanidades nas escolas, 1º ed., Maceió: Editora Café com Sociologia, 2019.
PSICOMOTRICIDADE: ALFABETIZAÇÃO E LETRAMENTO POR MEIO DO MOVIMENTO
Authors: Andrade de Souza Jean Cesar , Cunha dos Santos Amanda , Andrade de Souza Joana Roseli
Published: August 2020

Introdução: Desde o início da vida até os últimos dias de existência mundana, os seres humanos estão em constante movimento de aprendizagem. Diante disso, inúmeros são os conhecimentos adquiridos e ressignificados à nossa vontade. Dentre estes, a alfabetização apresenta papel de destaque no exercício da cidadania. Objetivo: Analisar a relação entre a psicomotricidade e os processos de letramento e alfabetização, com o intuito de ampliar o entendimento dos profissionais da educação à respeito dessa etapa importante à cidadania. Método: Adotou-se a pesquisa de revisão sistemática de literatura, com base em artigos científicos publicados nos últimos 10 anos nas bases de dados: Google Acadêmico, Periódicos Capes e SCIELO (Scientific Electronic Library Online). Para busca e seleção dos artigos científicos utilizou-se os descritores: letramento, alfabetização e psicomotricidade (literacy, literacy and psychomotricity), limitando-se em artigos nas Línguas Portuguesa e Inglesa. Após a aplicação dos filtros de seleção, realizou-se a leitura dos resumos de maior relevância, e aqueles com pertinência ao tema foram lidos na íntegra e fichados, e os resultados elencados em tabela. Resultados: Foram fichados total de 10 artigos. Verificou-se que todos os estudos defendem o uso da psicomotricidade, não só como uma alternativa, mas sim, como parte vital no processo de alfabetização. Também foi observado que deficiências psicomotoras, podem causar atraso e dificuldade de aprendizagem. Considerações Finais: Os elementos psicomotores quando bem organizados entre si e estimulados por atividades livres ou organizadas, de maneira lúdica e intencional, apresentam associação positiva à alfabetização.
Determination of Optimum Condition of Lead (Pb) Biosorption Using Dried Biomass Microalgae Aphanothece sp.
Authors: Keryanti Keryanti , Mulyono Edi Wahyu Sri
Published: August 2020

Contamination of lead (Pb) in water due to domestic and industrial activities can endanger the environment and human health. One of the heavy metal waste treatments is adsorption using microorganisms (biosorption). In this study, dried microalgae Aphanothece sp. used as biosorbent for binding Pb in aqueous solution. Biosorbent was prepared from the 14 days cultivation of microalgae in a photobioreactor system which was then dried and mashed to the size of 45 mesh. Pb metal biosorption experiments were carried out in a batch system at various initial concentration variations (3.9–18.6 mg/L) and contact times (30–180 minutes) to find the optimum conditions of the biosorption process. The concentration of Pb in solution was analysed using the Atomic Absorption Spectroscopy (AAS). The results of the experiment showed that the highest removal efficiency of Pb metal in the initial concentration variation of 18.6 mg/L and contact time of 30 minutes was 99.9 % with an absorption capacity of 185.64 mg/g. Pb metal adsorption data at equilibrium conditions follows the Langmuir isotherm model equation with R2>0.9. Biosorption kinetics using dried biomass of Aphanothece sp. following the pseudo second-order kinetics model. The results of this study provide an overview of the potential microalgae as Pb metal biosorbent in wastewater treatment on a larger scale.
Helle Prosdam and Thomas Elholm (eds.), Dialogues on Justice: European Perspectives on Law and Humanities (Berlin: de Gruyter, 2012)
Authors: Coffey Donal
Published: August 2020

This recent volume is the result of an outgrowth of the Nordic Network of Law and Literature. It is structured around four themes: Law and Humanities, History, Memory and Human Rights, Forgiveness and Law, and Justice, Culture and Copyright. Each of these themes attracts contributions from two distinguished authors, and there is a further Prologue and Epilogue that adds to the discussion on the four themes.
Anne Quinney (ed.), Paris – Bucharest, Bucharest – Paris, Francophone Writers from Romania (Amsterdam: Rodopi, 2012)
Authors: Brodeala Elena
Published: August 2020

I was born, raised and I am currently living in post-communist Romania.
A reply to the reviewer of “Totalitarismo, democrazia, etica pubblica. Scritti di filosofia morale, filosofia politica, etica”
Authors: Sollazzo Federico
Published: August 2020

Dear Professor Baruchello, I thank you for your articulate review, yet permit me to specify some points with which I disagree.