bluuebunny/crossref_metadata_2025 huggingface dataset:
Representasi Konsep Uchi-Soto pada Penerjemahan Teineigo dalam Subtitle Drama Jepang
Authors: Salsabila Dhia Ardhina , Hariri Tatang
Published: May 2024

This study uses a qualitative descriptive method to analyze the representation of the uchi-soto concept as a form of teineigo in Japanese and its translation into Indonesian. The uchi soto concept as an in-group and out-group concept has a very strong influence on language in Japanese society. This study aims to find out how the concept of uchi soto is represented as a form of honorific, to analyze the form of teienigo translation and changes in meaning that occur in the translation. The results of the study shown that the concept of soto is more often used in the -masu form while the concept of uchi is more often used in the -desu form. Translation results contained in the drama subtitles of The Journalist (2022) and Pretty Proofreader (2015) shown that there are several changes in meaning made by the translator. This is caused by the different translators in each drama and translator's lack of understanding of these two concepts. The analysis of the form of honorific translation illustrates the complexity of the translation process which affects the equivalence of the translation.
Matahara dan Patahara: Tantangan Hak Cuti Mengurus Anak Dalam Budaya Korporasi Jepang
Authors: Dehars Rizky Aurelia Putri
Published: May 2024

This research discusses about maternity harassment and paternity harasement that is happening in Japanese work environment which linked to Japan;s declining population. The writer used qualitative method and literature study from Japanese ministries websites, Japanese and international news article,as well as local and international journal. From teh data that has been gathered and analyzed, it can be concluded that maternity harassment and paternity harassment was caused by Japanese corporations long-hours work environment. Those who can’t comply to the rules were seen as incompetent and jeopardized the company. However, this mistreatment and the Japanese work environment were also causing Japanes population to decline.
Understanding the Cultural Reality of Shinobi through the Anime Series of Naruto & Naruto Shippūden
Authors: Budiarto Gema
Published: May 2024

Naruto and Naruto Shippūden are the anime series adapted from Masashi Kishimoto’s manga. The Naruto series aired in Japan from 2002-2007, while Naruto Shippūden was from 2007-2017. These animes are interconnected, Naruto is part one and Naruto Shippūden is part two. These animes took some of the original traditions of the Shinobi though not the same. Indeed, Shinobi is real and not a myth. If studied historically, Shinobi were considered ancient warriors of Japan other than the Samurai-侍. Nevertheless, the theory about the birth of the Shinobi is complicated to trace, but Shinobi existed in feudal Japan, especially during the Sengoku Jidai-戦国時代. This research tries to examine the cultural reality and facts of the Shinobi in the Naruto and Naruto Shippūden series. The method used in this research is descriptive qualitative. The result of this study shows that Naruto and Naruto Shippūden adopted the reality of the Japanese Shinobi. Some of the original Shinobi elements were adopted in this anime such as the use of weapons, hand seals, the use of nature elements, and so on. Through these animes, viewers are invited to recognize the traditions of the Japanese Ninja world.
THE TRANSFORMATION MODEL OF ISLAMIC BOARDING SCHOOLS IN CURRICULUM DEVELOPMENT SEEN FROM LOCAL RELIGIOSITY TOWARDS GLOBAL IDEALITY AT THE RAUDLOH AL THOHIRIYAH ISLAMIC BOARDING SCHOOL KAJEN PATI
Authors: Syafiq Abdullah , Rahardja Edy
Published: May 2024

The transformation model of pesantren education in curriculum development is seen from local religiosity towards global ideality at the Raudloh Al Thohiriyah Kajen Pati Islamic boarding school. Regarding the transformation of education in curriculum development, based on the description and existing problems, this study has the following objectives: 1). To knoweducational transformation model of the Raudloh Al Thohiriyah Kajen Pati Islamic boarding school, and 2) To find out the implementation in the development of the Raudloh Al Thohiriyah Kajen Pati Islamic boarding school curriculum seen from local religiosity towards global ideals. The data collection method in this thesis in this study will later use a qualitative research methodology with a participatory approach through multilevel stages,then EngineeringAnalysis of this data using analysis (Triangulation) is described. Triangulation analysis is an attempt to synthesize and group data from observations, interviews, and FGDs.in this research is descriptiveanalytical.The results of this study conclude that 1) Transformation of the educational curriculum has a very important role and use, because this curriculum transformation directs all educational activities carried out by an institution. 2) The main factor inhibiting educational transformation is the conservative view. The meaning is that the current situation is the best and does not need to be changed. This view is still held by some Islamic boarding school caretakers, resulting in setbacks. 3) Development of curriculum materials to improve the quality of education at the Raudloh Al Thohiriyah (Al Mardliyah) Islamic Boarding School of Kajen Pati comes from the curriculum components and learning completeness, curriculum content, local content, self-development, life skills education, study load regulation.
EFFECT OF SUSTAINABILITY DISCLOSURE PERFORMANCE INDICATORS ON PROFIT MANAGEMENT WITH COMPANY SIZE AS A CONTROL VARIABLE
Authors: Hanifah Risti Ulfi , Wijayanti Provita
Published: May 2024

Sustainability disclosure is a disclosure that can communicate to all stakeholders about economic, environmental, and social performance in realizing sustainable development goals. Stakeholder demands to meet the need for more transparent and accountable disclosure by organizations and pressures companies to collect, process, manage, and publish sustainability information. This will be reflected in a more accountable and transparent management of the cost of capital, which can affect the level of revenue management in the company's historical reports. The interesting question is the disclosure of sustainability with the level of profit management in the company over the company's more transparent revenue and the absence of profit manipulation practices carried out by management. The concept of discretionary accruals gives the understanding that management can manipulate accrual income and is usually used to achieve the desired income.This study aims to test empirical evidence regarding the influence of sustainability report indicators on profit management through discretionary accruals with company size as a control variable carried out on companies listed on the Indonesia Securities Exchange in 2018-2021. The samples in this study used non-financial companies with a total sample of 82 selected companies with purposive sampling techniques. This study used Partial Least Squares (PLS) based on variance as a measuring instrument. The data obtained were analyzed using the WarpPLS 5.0 application.Based on the findings, it shows the importance of the role of sustainability reports in terms of each aspect in their influence on profit management. It was concluded that the sustainability report consisting of economic and social aspects has a positive effect on profit management, while the environmental aspect negatively affects profit management, profit management negatively affects the size of the company as a control variable.
THE EFFECT OF CUSTOMER REVIEWS, PRODUCT PRICE, AND SERVICE QUALITY ON PURCHASE DECISIONS WITH MODERATED BRAND IMAGE IN E-COMMERCE APPLICATIONS
Authors: Wikantari Maria Assumpta
Published: May 2024

This study aims to analyze the effect of customer reviews, product prices and service quality on purchasing decisions moderated by brand image. The population in this study is 100 residents of the city of Jakarta, whose criteria have been determined. The sample selection was carried out using a purposive sampling method, by taking 100 Jakarta residents with an age range of 20-40 years as the sample in this study.The analytical techniques used in this study are: 1) Validity Test, 2) Reliability Statistics, 3) Classical Assumption Test consisting of Normality Test, Multicollinearity Test, Heterocystista Test, Autocorrelation Test, 4) Multiple Linear Regression, 5) Hypothesis Test consisting of from Coefficient Test and Partial Influence Test (t) and MRA.The results of this study indicate that customer reviews have no effect on purchasing decisions, this is evidenced by the t value of 0.747. Product prices have a significant effect with a t-value of 0.460. Service quality has a partial effect on purchasing decisions with a t value of 3.378. Customer reviews, product prices and service quality simultaneously influence purchasing decisions with an f value of 4.451. Brand image cannot mediate the relationship between customer reviews, product prices, service quality on purchasing decisions, and none of them are significant
On some 𝑝-adic and mod 𝑝 representations of quaternion algebra over ℚ𝑝
Authors: Hu Yongquan , Wang Haoran
Published: May 2024

Let 𝐷 be the nonsplit quaternion algebra over

Q
p

\mathbb{Q}_{p}

.
We prove that a class of admissible unitary Banach space representations of

D
×

D^{\times}

of global origin are topologically of finite length.
Recent mortality rates due to complications of medical and surgical care in the US
Authors: Mattiuzzi Camilla , Plebani Mario , Lippi Giuseppe
Published: May 2024

Objectives

Medical errors and complications pose a major threat to the safety of healthcare systems worldwide. This article was hence aimed at determining the current burden of complications of medical and surgical care in the US.

Methods

We searched the latest version of the US Centers for Disease Control and Prevention (CDC) WONDER online database (years 2018–2022) using ICD-10 codes Y40-Y84 (complications of medical and surgical care).

Results

The age-adjusted death rate for complications of medical and surgical care increased from 1.17 × 100,000 in 2018 to 1.49 × 100,000 in 2021, but then declined to 0.85 × 100,000 in 2022. The gender-specific analysis showed a similar trend, with the age-adjusted death rate values always being higher in men than in women. A clear age-dependent relationship was also found in the crude mortality rate for complications of medical and surgical care, as higher death rates were observed in older patients.

Conclusions

This analysis reveals that the burden of complications of medical and surgical care has increased over time, especially during the COVID-19 pandemic, but has then considerably declined in 2022. However, root cause analysis and actions are still needed for preventing the still noticeable consequences of medical complications.
Bees (Hymenoptera: Apoidea) diversity and synanthropy in a protected natural area and its influence zone in western Mexico
Authors: Razo-León Alvaro E. , Huerta-Martínez Francisco M. , Moya-Raygoza Gustavo , Muñoz-Urias Alejandro
Published: May 2024

Mexico’s wild bee richness includes 1,800 species, however, there is a lack of studies on this group in the country. Therefore, it is of extreme importance to intensify the study on this group of insects, so this research aimed to compile an inventory of the melittofauna of Sierra de Quila, Jalisco, Mexico, to evaluate alpha diversity in different types of vegetation, and assess which of the most abundant bee species are synanthropic (organisms that live near and benefit from humans and their environmental modifications). Bees were collected and recorded over two years between 10:00 and 16:00 h, in the flora and fauna protection area of Sierra de Quila and its region of influence, using entomological nets. A total of 15,641 individuals of 233 species belonging to 66 genera and five families were recorded, of which Apidae is the best represented family with 88 species, followed by Halictidae with 54 species, Megachilidae with 49 species, Andrenidae with 24 species, and Colletidae with 18 species. Tropical dry forest showed a higher richness of wild bees than the pine-oak forest, eight species were asynanthropic and only five species were eusynanthropic. Our results show that Sierra de Quila is one of the richest areas in bee species for the state of Jalisco, making it an important area for the conservation of this group of native pollinators.
An experimental validation of diffusion-based devolatilization models in extruders using post-industrial and post-consumer plastic waste
Authors: Chung Chi Nghia , Marschik Christian , Akhras Mohamad Hassan , Höftberger Thomas , Burgstaller Christoph , Steinbichler Georg
Published: May 2024

Extrusion is a key process in mechanical recycling. In a degassing step, volatile components, including all impurities and moisture, are removed from a polymer melt to ensure consistently high quality of the recyclates. Predicting devolatilization performance is therefore of interest in the design of degassing screws; in the plastics industry, it also plays an important role in the transition from a linear to a circular economy. Using two different devolatilization models, we first modelled the degassing process of a lab-scale twin-screw extruder and an industrial-scale recycling single-screw extruder. We then predicted the devolatilization performance of both machines, validated the results with experimental data obtained from emissions tests carried out with post-industrial and post-consumer polypropylene materials and performed linear regression analysis to compare our two models in terms of predictive quality. Our results showed that both models are equally suitable for reliable prediction of the devolatilization performance.
Guiding light with surface exciton–polaritons in atomically thin superlattices
Authors: Elrafei Sara A. , Raziman T. V. , de Vega Sandra , García de Abajo F. Javier , Curto Alberto G.
Published: May 2024

Two-dimensional materials give access to the ultimate physical limits of photonics with appealing properties for ultracompact optical components such as waveguides and modulators. Specifically, in monolayer semiconductors, a strong excitonic resonance leads to a sharp oscillation in permittivity from positive to even negative values. This extreme optical response enables surface exciton–polaritons to guide visible light bound to an atomically thin layer. However, such ultrathin waveguides support a transverse electric (TE) mode with low confinement and a transverse magnetic (TM) mode with short propagation. Here, we propose that realistic semiconductor–insulator–semiconductor superlattices comprising monolayer WS2 and hexagonal boron nitride (hBN) can improve the properties of both TE and TM modes. Compared to a single monolayer, a heterostructure with a 1-nm hBN spacer separating two monolayers enhances the confinement of the TE mode from 1.2 to around 0.5 μm, while the out-of-plane extension of the TM mode increases from 25 to 50 nm. We propose two simple additivity rules for mode confinement valid in the ultrathin film approximation for heterostructures with increasing spacer thickness. Stacking additional WS2 monolayers into superlattices further enhances the waveguiding properties. Our results underscore the potential of monolayer-based superlattices as a platform for visible-range nanophotonics with promising optical, electrical, and magnetic tunability.
Happiness and the Biopolitics of Knowledge: From the Contemplative Lifestyle to the Economy of Well-Being and Back Again
Authors: Cimino Antonio
Published: May 2024

The article explores the relationship between two different approaches to happiness and knowledge, that is, the contemplative model and the economistic and instrumental model. Whereas the former equates happiness with the contemplative life, the latter separates happiness from knowledge and subordinates both to what present-day policy-makers call “the economy of well-being.” While biopolitical modernity seems to have rendered the contemplative model obsolete and purposeless, the article suggests reviving the contemplative lifestyle, by putting forward three arguments. First, it contends that we should challenge the economistic and instrumental model, by reaffirming the principle that knowledge and happiness are primarily intrinsic values and ends in themselves. Second, the two models do not necessarily exclude each other and we should strive to combine them. Third, the envisaged integration of the two models requires that we revise them significantly. The elitist and metaphysical character of the traditional contemplative model must be abandoned as it is no longer palatable to modernity. Also, the primacy of economic and instrumental rationality that defines the modern biopolitics of knowledge must be questioned.
Segmentation of multivariate autoregressive sequences
Authors: Lipeika Antanas , Lipeikienė Joana
Published: May 2024

There is not abstract.
Reasons that induce driving while intoxicated young adult
Authors: Casique Leticia Casique , Aguiire Alicia Alvarez , Santana Mercedes Velasco , Azúa Maria Vargas Cleopatra , Leon Armando Rico
Published: May 2024

Alcohol consumption is one of the leading causes of death, disease and accidents. Driving a vehicle under the influence of alcohol, causes a great risk, to do because this is needed for the coordination of all the senses and is known that spirit you reduce the responsiveness of the brain. In this analysis, some of the young adult Reasons that induce driving while intoxicated is described. It is evident that alcohol causes feelings of power, superiority and freedom, which favors the young adult run the risk of driving while intoxicated endangering Their own physical integrity and of third persons not to mention property damage.
Medical treatments for incurable diseases, palliative therapy
Authors: Lu Da-Yong , Wu Hong Yig , Shen Ying , Xu Bin , Lu Ting-Ren
Published: May 2024

Chronic and aggressive diseases are commonly incurable. Palliative and nursery care are newly practiced that aims to disease managements outside normal therapy. Better medical service and symptom alleviations of incurable congenital diseases can satisfy patients with reduce therapeutic costs and a long period of times. In this article, relevant medical disciplines and drug developments are provided—from technique detail to medical knowledge as well as clinical applications in a broader-range.
Egg quality traits, phenotypic correlations, egg and yolk weights prediction using external and internal egg quality traits of Japanese quails reared in Calabar, Nigeria
Authors: B Okon , LA Ibom , A Dauda , VN Ebegbulem
Published: May 2024

Three hundred freshly laid eggs collected from 12 weeks old brown Japanese quails on deep litters fed 18% CP and 2700 kcal ME/kg ration and water ad libitum. External egg quality traits measured included egg (weight and width) and yolk (weight, height and width). Data collected were used to estimate descriptive statistics, phenotypic correlations and to predict egg and yolk weights. Results of phenotypic correlation of external egg traits investigated expressed mostly non-significant (p>0.05) both positive and negative low values with the exceptions of two higher, negative significant (p<0.01) correlations observed between egg weight and egg length (r= – 0.721) and egg weight and shell thickness (r= – 0.616). Similarly, results of phenotypic correlations of internal egg traits expressed mostly non-significant (p>0.05) both positive and negative low values with the exceptions of very high negative correlation coefficient (r= – 0.802) between yolk weight and albumen width and moderate negative correlation coefficient (r= – 0.561) between albumen height and albumen width. The only moderate positive significant correlation (r=0.519) obtained in this study was between yolk weight and albumen height. The regression estimates of parameters and coefficient of determination for simple (one trait) and multiple (two traits and for predicting egg and yolk weight sh6wed very low non-significant associations/interrelationship. But with three to five traits fitted into the multiple linear regression equations, highly significant (p<0.001) associations/interrelationships were obtained for egg and yolk weights. Egg and yolk weights can be predicted using external and internal egg traits measurements with two external traits (egg length and egg width) and two internal traits (albumen height and albumen width) best predicted egg and yolk heights respectively.
Biogenesis and function of microRNAS from plants, animals and fungi applicable in health and food biotechnology
Authors: Gutiérrez Sehom Rivera , Durán Noé Valentín
Published: May 2024

MicroRNAs are small non-coding RNAs found in plants, animals and fungi. They are involved in developmental, metabolic, growth and reproduction processes. They modulate these processes by regulating target mRNAs by binding to them through base complementarity, and with the help of an enzymatic complex, they cleave the mRNA, or interrupt its translation into protein. Its biogenesis in plants occurs within the nucleus, to later be exported to the cytoplasm where it will take its regulatory action. In animals, biogenesis begins in the nucleus, but unlike plants, it is completed in the cytoplasm. A biosynthetic mechanism has not been established in fungi, although it could be similar to that in plants due to the nature of the fungal transcripts. MicroRNAs can be used as key biomolecules in the solution of health problems, in the improvement of plants of agronomic interest and in the optimization of bioprocesses to obtain industrial products of food interest. Furthermore, they have been proposed as strategic biomolecules in the design of nutritional tables that offer a better quality of life to people. Agronomically, its study focuses mainly on improving the characteristics of crops of commercial interest, as well as combating pests that affect the production of fruits, vegetables and grains. For this reason, microRNAs are being proposed as cutting-edge molecules for solving health food problems worldwide.
Issues of prevalence, pathogenesis, clinical features, diagnosis and treatment of the associated course of non-alcoholic fatty liver disease and diagnosis of growth hormone deficiency: Brief overview of articles
Authors: ShA Khudaybergenov , RT Khaydarova , DA Alieva , YuM Urmanova
Published: May 2024

Growth hormone deficiency (GHD) is associated with insulin resistance, visceral obesity, type 2 diabetes, dyslipidemia, and NAFLD. The diagnosis of GHD should be suspected in all patients with hypothalamic-pituitary axis disorders. If GHD is not adequately treated before or after transplantation, the presence of NAFLD can lead to rapid progression of NASH to cirrhosis. Future research should focus on developing early detection strategies as well as biochemical and imaging techniques to monitor patients with PG for progression of NAFLD and NASH. Randomized controlled trials should evaluate optimal treatment strategies in this cohort and balance the effects on NAFLD, glucose metabolism, and diabetes risk, as well as the long-term effects on fibrosis and cancer risk. The potential of GH therapy in patients with NAFLD without GH deficiency needs to be further studied with long-term follow-up. It is important to note that the standard treatment for these patients should be a multidisciplinary approach with close collaboration between hepatologists and endocrinologists, focused on the needs of the individual patient.
Canine Leishmaniasis (CanL); a public health threat in Ghana
Authors: Razak Mohammed Raji Abdul
Published: May 2024

Canine Leishmaniasis (CanL) is a protozoal disease caused by Leishmania species and transmitted by the female phlebotomine sand fly (which serves as a vector for the parasite) among animals and humans. The disease is of great importance to public health, due to its zoonotic nature, and the role of dogs as the natural reservoir of the disease. An important factor that helps in the continuous perpetuation of the parasite and for that matter the disease is the ability of the infective form of the parasite (metacyclic promastigote) to transform into amastigote in the host cells, and outsmart the host’s immune mechanism. These phenomena among other factors, poses a great risk of spreading the disease to susceptible hosts (humans and animals). Three forms of the disease have been identified, namely; visceral (VL), cutaneous (CL) and mucocutaneous (MCL). Leishmaniasis control has been categorized into direct method, targeted at infectious dogs and indirect method, targeted at the vector. In conclusion, human cutaneous leishmaniasis (HCL) is endemic in certain areas of the country, however, there is no data on cases of canine leishmaniasis in the country. It is recommended that, in discussing strategies to curb human leishmaniasis, stake-holders should factor in the role of dogs and for that reason, canine leishmaniasis (CanL).
Migratory foreign body of hypopharynx
Authors: Gupta Nitin , Gulati Ankit , Singhal Surinder K , Sharma Jyotika , Seigell Sunakshi
Published: May 2024

A 22-year-old male, tailor by profession presented to Ear Nose Throat (ENT) emergency with accidental ingestion of needle while cleaning his teeth which was associated with difficulty in swallowing (more for solids than liquids) and irritation in throat. On clinical examination no foreign body was seen. Diagnosis of extraluminal migration can be done with the help of Computed tomograms (CT) scans which can provide exact location of foreign body before surgical exploration. C-arm can be utilized specially in metallic foreign bodies to localize during the surgery. In our case both CT and C-Arm were used and foreign body was removed by transcervical route without any complication. In case of absence of foreign body on intraluminal assessment, possibility of migration of foreign body should be completely ruled out and patient should be investigated accordingly.
Volanesorsen and familial chylomicronemia syndrome
Authors: Barros C Trigo , Varela R Boente , González, A Martínez , Sas Fojón M De
Published: May 2024

Objective: To reduce severe hypertriglyceridaemia and episodes of pancreatitis in patients with familial chylomicronemia syndrome (FCHS), in whom the response to diet and triglyceride (TG) lowering treatment has not been sufficient. Method: A 46-year-old woman diagnosed with genetically confirmed FFCS, with heterozygous presence of two variants and very severe elevation of triglycerides (≥2000 mg/dL), multiple admissions for acute pancreatitis since the age of 19, with associated side effects such as pancreatoprive Diabetes Mellitus with need for insulin and severe hepatic steatosis with grade I fibrosis diagnosed by liver biopsy. Given the intolerance to fibrates and insufficient response to diet and high doses of ω-3 fatty acids, we started treatment with Volanesorsen. Result: After 6 admissions for acute pancreatitis from January to April 2020, treatment with Volanesorsen was started on 7 August. Platelets at the start of treatment were 283x103/mm3 and triglycerides 1878 mg/dL. Platelet monitoring was performed every 2 weeks and at all times the figure remained >140x103/mm3. The treatment was well tolerated and after three months, the targets for continuing Volanesorsen were reached, reducing TG by more than 25% and reaching 624 mg/dL with platelets in the normal range. Conclusion: Volanesorsen is indicated as an adjunct to diet in adult patients with genetically confirmed FQS at high risk of pancreatitis, in whom the response to diet and triglyceride-lowering treatment has not been sufficient.
Agenesis of the gallbladder, a rare congenital anomaly that can mimic chronic cholecystitis: case report
Authors: Marzouk Sawssen Ben , Ferjaoui Wael , Jelassi Adel , Hedi Mannai Mohamed , Bechir Khalifa Mohamed
Published: May 2024

Agenesis of the gallbladder is a rare congenital malformation caused by the failure of the cystic bud to develop in the gallbladder, which may or may not be associated with other biliary malformations. It is an anomaly of variable symptomatology, with 50% of patients presenting symptoms mimicking biliary colic; it may be discovered by chance during surgery, while 15% may present fatal fetal malformations. When symptomatic, it is interpreted as chronic cholecystitis, with a narrowed appearance of the gallbladder on abdominal ultrasound, as the biliary structures may resemble those of a gallbladder, demonstrating the need for radiologists and surgeons to be aware of this diagnosis and its management, in order to avoid unnecessary surgery. In this article, we present a case of gallbladder agenesis in a young man who presented with hepatic colic-like symptoms suggestive of cholecystitis. The gallbladder was not well visualized on ultrasound, simulating chronic cholecystitis, and a Bili MRI concluded that the gallbladder was absent, thus avoiding surgery.
Prediction of remaining service life for flexible pavement in the Southern Central States using FWD parameters
Authors: Bastola Nitish R , Souliman Mena I , Dessouky Samer , Daoud Raja
Published: May 2024

Various Departments of Transportation (DOTs) in the South-Central States and abroad have extensively used Non-Destructive Testing (NDT) surface deflection bowl data. The primary purpose of using deflection-based NDTs in network-level assessment is to identify a section of pavement in need of further investigation at the project level. The falling weight deflectometer (FWD) test is a common NDT-based test that is used by transportation agencies to assess the performance of flexible pavement.This research concentrates on simulating the deflection produced by FWD devices using 3-D Move software. Simulations based on software will decrease the need for lengthy FWD testing in the field. In the study, ninety-seven (97) pavement sections from Arkansas, Louisiana, New Mexico, Oklahoma, and Texas are used for simulation, analysis, and verification of FWD testing. The deflection values produced from software simulations were found to be strongly correlated with field test findings. In addition, the simulated deflection values were used to develop and validate various deflection bowl parameters. In this study, the normalized comprehensive deflection ratio and the normalized comprehensive area ratio are two key characteristics that were validated and produced. Eventually, load-induced impacts using these parameters are effectively analyzed in order to anticipate the remaining service life of flexible pavement structures. The prediction of the remaining service life will be an efficient tool for different DOTs and transportation agencies to initiate the rehabilitation work in time and economically.
Piezo1-dependent inhibition of background potassium current in the rat bladder smooth muscle cells
Authors:   Bogomoletz Institute of Physiology National Academy of Sciences of Ukraine, Kyiv, Ukraine, Yeliashov S.I. , Sharopov B.R. ,   Bogomoletz Institute of Physiology National Academy of Sciences of Ukraine, Kyiv, Ukraine, Shuba Y.M. ,   Bogomoletz Institute of Physiology National Academy of Sciences of Ukraine, Kyiv, Ukraine
Published: May 2024

The smooth muscle layer of the urinal bladder (detrusor), along with the urothelium, has autonomous mechanosensitivity and serves as a main sensitive receptor in the organ. Piezo1, together with TREK-1 channel, could play a role of local mechanoreceptors in bladder detrusor smooth muscle (DSM) cells. Piezo1 is a so-called “true” mechanosensitive calcium-permeable ion channel, sensitive to pressure, shear stress, and is activated by pharmacological agonist Yoda1. Using patch-clamp and microfluorescence calcimetry, an unexpected effect from Yoda1 was shown, that is inhibition of rest K+ currents at depolarizing command voltage up to +80 mV. The functional presence of Piezo1 is confirmed by Yoda1-induced rise of intracellular Ca2+ concentration in DSM cells, this was visualized using a Ca2+ sensitive dye Fluo-4 AM, and polymerase cyclic reaction with reverse transcription. In conclusion, Piezo1 channels present in DSM cells and are selectively activated with Yoda1, that causes the inhibition of resting potassium currents.
The total saponins from Chinese onion exert pronounced anti-hypercholesterolaemia activity in mice
Authors: Li L. , Wang L.T. , Wang Y.H. , Xu J.W. , He X.J.
Published: May 2024

Chinese onion (Allium chinense G. Don) is an edible vegetable as well as a traditional Chinese medicine. It is rich in steroidal saponins and possesses broad health benefits. In this study, the optimal extraction protocol of the total saponins from Chinese onion (ACS) was explored, and the content of the total steroidal saponins in ACS reached 56.62%. Network pharmacology was applied to predict the related signalling pathways and targets between the main phytochemicals in ACS and hypercholesterolaemia. Enrichment analysis showed that ACS might intervene hypercholesterolaemia through the PI3K-Akt signalling pathway. Meanwhile, cholesterol-lowering effects were verified by ACS intervention in high-cholesterol diet-induced hypercholesterolaemia in Kunming mice. Compared with the model group, the TC and LDL-C levels of mice were decreased and the HDL-C level increased significantly after administration of ACS at a dose of 200 mg kg−1 day−1. The body weight gain, liver index, and atherosclerosis index all decreased dramatically. ACS could significantly reduce the fat content in the liver and reduce the number of fat droplets from the haematoxylin and eosin (H&E) staining of mouse liver. The immunohistochemical staining indicated that ACS could up-regulate the expression of PI3K protein in the liver, thus playing an anti-hypercholesterolaemic role. This study indicated that ACS exhibited significant therapeutic and preventive effects on hypercholesterolaemia, and exerted anti-hypercholesterolaemia through the PI3K-Akt signalling pathway.
An epidemic and economic growth. A medium-term perspective
Authors: Bolińska Monika , Dykas Paweł , Tokarski Tomasz , Wisła Rafał
Published: May 2024

The described model of economic growth under conditions of an epidemic does not directly refer to the social and economic situation in the years 2020 and 2021, i.e. to the COVID-19 pandemic. It is aimed to identify the consequences of any epidemic leading to severe social losses (high percentages of the infected and dead, limited interpersonal contacts as a result of lockdown, a lowered level of general individual and social well-being) and economic losses (a fall in production as a result of the collapse of aggregate demand and a reduction in the supply capacity of the economy, and consequently a decreased rate of capital accumulation). The described epidemiological-economic model combines the SIR epidemiological model from 1927 (with its modification proposed in 2020 by Bärwolff) and the neoclassical growth model proposed by Solow in 1956. The authors expanded the concept by lockdown restrictions with various levels of their severity, considering specific rules for their implementation, and by guidelines for scenario analyses of changes in the value of social and economic activity index, in the value of aggregate production, in the capital stock accumulated in the economy and in social utility. The effect of an epidemic on medium-term economic growth was also considered, for various levels of economic development (measured by the distance of input capital stock from that formed in a long-term equilibrium in the Solow model). The principal conclusions drawn from the discussion are listed below. First, the introduction of the same restrictions imposed on social and economic activity throughout the territory of a country poses a considerable risk of error in assuming a uniform spread of the epidemic. Second, a rapid introduction of lockdown measures has a stronger effect on accumulated social and economic activity than a continual process of gradual imposing and lifting restrictions on that activity. Third, a scenario of a rapidly imposed severe lockdown has the most drastic consequences for the economy, causing both the sharpest drop in production, the longest time of remaining on the path of relatively lowest growth, and the most dramatic expected accumulated decrease in production. Similar conclusions are drawn as to the changes in social utility.
Reductions in payments to the State Fund for the Rehabilitation of Persons with Disabilities (PFRON) as a tool to reduce non-wage labour costs in enterprises
Authors: Koza Andrzej , Politaj Adriana
Published: May 2024

In this study, the authors attempted to identify employment costs, with particular emphasis on non-wage employment costs in terms of payments to the State Fund for the Rehabilitation of Persons with Disabilities (PFRON) and the possibility of their reduction. The main purpose was to identify and verify the effectiveness of legal and financial solutions aimed at stimulating Polish enterprises to employ workers with reduced competitiveness on the labour market and constituting a form of compensation for their employment in the context of reducing non-wage labour costs. The following research hypothesis was formulated: applying financial penalties for not employing persons with disabilities is not severe enough for enterprises to significantly change their attitude towards employing such persons, even in the context of their systematically growing number, because the multidimensional costs of employing persons with disabilities are more severe than the penalties paid for not employing them. The conducted research and literature review allowed for identifying the basic factors and correlations between the severity of penalties and the employment level of persons with disabilities. A strong positive correlation was observed between their employment rate and the increase in the basis for imposing penalties. Employers, having noticed the increasing amounts of penalties, tried at least not to increase the basis for their calculation and systematically aimed at supplementing employment or obtaining reductions in payments as a result of a lower ratio or the amount of payments made to the Fund owing to the cooperation with the employers of people with disabilities authorised to provide them. The research covered the years from 2018 to 2022, the subjective scope included enterprises with at least 25 full-time employees and subject to the obligation of employing persons with disabilities. The following research methods were used: critical analysis of source literature and legal acts, descriptive method, statistical analysis and correlation analysis based on the Pearson correlation coefficient.
Strategie wspierania zdolnych podopiecznych pieczy zastępczej
Authors:   Akademia Bialska im. Jana Pawła II, Ruszkowska Marzena
Published: May 2024

The issue of gifted children growing up in a natural family environment has been addressed quite widely. However, small amount of research regarding gifted children residing in the foster care environment is noticeable. At the same time, the issue of having, developing and supporting abilities is extremely significant, especially with regard to pupils of foster care environments deprived of their primary developmental environment, which is the family. Foster care environments can also effectively support the potential of their pupils. The publication is an attempt to answer the question of what support activities are undertaken in the foster care environment in relation to gifted pupils? The research method is case studies. The research indicates various forms of support for gifted pupils: the organization of additional activities, depending on the interests or abilities of the pupil or the financial support as the one they need for the future process of independence, as well as emotional support and others. At the same time, some differences are visible between the activities of institutional and family care, as the latter definitely more often uses the help of psychological and pedagogical counseling centers or organizations supporting gifted students, even if in the form of funded scholarships.
Karierowiczka i egoistka: opór polskich „bezkidek” wobec presji społecznej posiadania dzieci. Analiza przekazów na platformie TikTok
Authors:   Uniwersytet Warmińsko-Mazurski w Olsztynie, Ryndzionek Monika
Published: May 2024

This article delves into the phenomenon of intentional childlessness within the context of many societal pressures prevalent on he Internet and specifically on the social platforms. It encompasses an exploration of recent scientific research and inquiries into the choice of childlessness, with a focus on the #childfree movement on TikTok. The presented study of an author covers an analysis of Polish content related to intentional childlessness on TikTok, dissecting the methods of social shaming directed at individuals opting for a child-free lifestyle, the defensive strategies employed by the child-free community, and the psychological phenomenon of the “authority rule”. This research approach sheds some light on the complex social dynamics surrounding the decision to remain child-free in the face of societal expectations, offering significant insights into contemporary attitudes towards this contentious topic within the TikTok community. This particularly concerns childless women who are almost expected to embrace motherhood as an obligation. TikTok is their space for spreading their views and defending their own position.
O ROSTO, O NOME E A FALA: POÉTICAS E POLÍTICAS DA ESPECTRALIDADE NO ESCADÃO MARIELLE FRANCO
Authors: Palma Daniela
Published: May 2024

RESUMO O artigo propõe refletir sobre a espectralidade como efeito de sentido político produzido por meio da arte urbana na montagem de um monumento popular em homenagem a Marielle Franco, na cidade de São Paulo. Para isso, o estudo buscou observar como algumas forças periféricas acionadas no movimento de luto e memória por Marielle foram moldadas semioticamente na intervenção artístico-ativista. As análises focam em três elementos que compõem o monumento: o rosto de Marielle no retrato fotográfico, o nome próprio e uma fala citada. Em termos teóricos, o texto articula discussões sobre luto, agência, espectralidade, memória, alteridade e perspectivas periféricas sobre referências e legado. O trabalho interpretativo mostra como esses elementos projetam a ideia de legado, indicializam a indignação, estimulam a mobilização por justiça e igualdade e promovem o confronto ético com a alteridade.
Sociologia do trabalho e desigualdade social: o “valor social da força de trabalho”
Authors: Voswinkel Stephan
Published: May 2024

Resumo Este artigo visa contribuir para uma redefinição da relação entre a sociologia do trabalho e a teoria social, conectando percepções do marxismo e da teoria do reconhecimento com as da sociologia da cultura. Trabalho está sempre inserido em culturas do trabalho e em uma economia moral e deve ser analisado no contexto de vida no qual pessoas se confrontam com constrangimentos, normas e expectativas sociais e desenvolvem também, nesse trabalho de identidade, as suas orientações de trabalho. Este artigo defende uma referenciação mútua e mais forte entre a sociologia do trabalho e a sociologia da desigualdade social, o que torna necessária a reflexão sobre a importância da concepção de “classe”. O artigo esboça um conceito duplo de classe – no sentido de desacoplar a compreensão deste conceito como contradição entre capital e trabalho daquela de uma categoria sociocultural. Com o “valor social da força de trabalho” propõe-se aqui uma concepção que medeie categorias de reconhecimento e as percepções interseccionais da relação entre capital e trabalho.◊
Conhecimento, confiança e experiência clínica dos fisioterapeutas e equipe multiprofissional sobre reabilitação pulmonar
Authors: Faria Isabella Diniz , Mendes Liliane Patrícia de Souza , Schettino Renata de Carvalho , Rocha Bianca Louise Carmona , Alison Jennifer A. , Velloso Marcelo
Published: May 2024

RESUMO O déficit de conhecimento dos profissionais de saúde tem sido uma barreira para a expansão e implementação dos serviços de reabilitação pulmonar (RP), apesar dos seus benefícios comprovados para indivíduos com doença respiratória crônica (DRC). Objetivo: avaliar o preparo dos profissionais de saúde de dois municípios brasileiros para fornecer a RP no sistema público de saúde. Esse estudo, do tipo survey, foi parte de um projeto maior para implementação da RP no sistema público de saúde brasileiro. Foi utilizado um questionário autoaplicável para avaliar o conhecimento (19 questões), o treinamento (7 questões), a confiança (10 questões) e a experiência clínica (8 questões) dos fisioterapeutas (FT) e da equipe multiprofissional (EM), aplicado antes de um workshop sobre RP. No total, 44 FT e 231 EM responderam o questionário. A pontuação média de conhecimento foi de 10±3 para FT e 6±3 para EM. Poucos FT referiam ter “muita” experiência (25%) e confiança (22,7%) para realizar RP, bem como treinamento suficiente para realizar o teste de caminhada de seis minutos (27,3%). Ainda menos profissionais da EM relataram ter “muita” experiência (10%) e treinamento suficiente (4,8%) para realizar RP, assim como para planejar o programa educacional dos pacientes (10%) e ter confiança para encaminhar pacientes para a RP (6,5%). Este é o primeiro estudo a avaliar o preparo dos profissionais da rede pública de saúde no Brasil para fornecer RP. Notavelmente, tanto FT quanto EM têm baixo preparo para realizar RP nos municípios estudados, reforçando a necessidade de realização de educação continuada.
Physical therapy performance in post-COVID-19 rehabilitation: knowledge and experience of physiotherapists
Authors: Oliveira Ana Paula Santana de , Contelli Sthefani de Souza , Sanches Thifani Pessoa , Benatti Leandra Navarro , Trevisan Iara Buriola
Published: May 2024

ABSTRACT After the acute phase of COVID-19, many patients have persistent symptoms or develop sequelae, which leads them to seek physiotherapy rehabilitation services. Therefore, this study aimed to investigate the knowledge and experience of physiotherapists on the assessment and treatment of post-COVID-19 patients. The cross-sectional observational study was carried out with 73 physiotherapists using an online questionnaire about academic background, areas of expertise, knowledge about COVID-19, and knowledge and experience of assessment and treatment resources in post-COVID-19 rehabilitation, in addition to barriers to the care of these patients in the ambulatory care. Most physiotherapists had heard of post-COVID-19 syndrome, however, only 44% felt sufficiently informed about post-COVID-19 rehabilitation. There was a discrepancy between the degree of importance and experience with the frequency of use of assessment resources, especially the use of specific assessment instruments for skeletal muscle strength, mobility, and respiratory function, in addition to scales and questionnaires to assess disabilities, quality of life, and sleep quality. On the other hand, most reported the importance and had sufficient experience to treat post-COVID-19 patients using cheap and accessible resources. However, less than half use techniques related to respiratory muscle training and/or more sophisticated equipment. Thus, we conclude that most physiotherapists recognize the importance and report sufficient experience to assess and treat post-COVID-19 patients, however, there is a discrepancy between the assessment in the biopsychosocial context of the patient and the treatment process.