bluuebunny/crossref_metadata_2025 huggingface dataset:
„Klatka bez drzwi i bez klucza”. Analiza aspektów poznawczych i etycznych wybranych przedstawień artystycznych niepełnosprawności i osób z niepełnosprawnościami
Authors: Zamojska Eva
Published: September 2018

The aim of my paper is to analyze cognitive and ethical aspects of selected literary and film depictions of disabilities. Based on theoretical and methodological assumptions of sociology of literature and critical discourse analysis I set out to demonstrate how selected literary and film works depict situations and problems with social inclusion of people with disabilities. I concentrate on two questions: 1) How do artistic creations build non-disabled people's knowledge of the social situation and position of people with disabilities? 2) What ethical problems can such depictions involve?
Osoba z niepełnosprawnością w rozmowach kazachskich rodziców z dziećmi
Authors: Kulesza Ewa , Butabayewa Laura
Published: September 2018

The paper presents the issue of social transmission by Kazakh parents concerning disability, especially their knowledge of disability and content of conversations with their children. Diagnostic survey method, survey technique and the author's questionnaire with open-ended questions were used. The analysis of content of the written statements shows that the parental message in the inclusive group compared to the general population more strongly emphasizes the attitude of tolerance and nondiscrimination of the disabled peer. Research confirms the impact of social context on the knowledge, attitudes and the image of a person with a disability and these results are consistent with those of other authors.
Osoby niepełnosprawne w sytuacji podwójnego wykluczenia w wybranych krajach Afryki Południowej
Authors: Belzyt Joanna Iza
Published: September 2018

In South African countries education plays the important role in the context of double exclusion occurance of people with disabilities living in those areas. Factors like race, gender, social origin or disability affect social inequalities which powerful strength in society is strictly connected with a dominant ideology or state policy (eg. apartheid in South Africa). People with disabilities undergoing social exclusion caused by their social origin as African natives, simultaneously undergo exclusion caused by disability. In this context, apart from (the exclusion rooted in) the “heritage” of apartheid, one can also find a very meaningful factor folk beliefs, healers and shamans. Hence, disability, according to the particular area of the country and local folk beliefs, is perceived and understood as punishment or a thrown charm which eventually makes families being ashamed of their disabled children or relatives, force them to hide them for fear of ostracism, violence, ritual mutilation or death.
New organic-inorganic hybrid composites based on cellulose nanofibers and modified Laponite
Authors: Silva Jhonatan M. , Maturi Fernando E. , Barud Hernane S. , Constantino Vera R.L. , Ribeiro Sidney J.L.
Published: September 2018

The combination of cellulosic materials and clays, such as Laponite, can provide composites with superior optical and mechanical properties compared to pristine cellulose. Synthetic clays can also be used as a host matrix for the immobilization of luminescent complexes, as the incorporated complexes may present enhanced emission quantum efficiency, photo and thermostability compared to the non-immobilized ones. In this way, we, herein, report the preparation of luminescent composites through the incorporation of a Eu(III) complex [Eu3+(tta)n] containing Laponite (Lap) into cellulose nanofibers (CNF). The thermogravimetry results show that the obtained CNF/Lap@[Eu3+(tta)n] films present higher thermal resistance than the CNF film. The Eu3+(tta)n species were found in the composite structure with preserved luminescence characteristics, and no leaching or degradation of the organic ligand was observed with the preparation of the composites.
The Motherhood Penalty: Is It a Wage-Dependent Family Decision?
Authors: Gafni Dalit , Siniver Erez
Published: September 2018

Recent studies have shown that even highly skilled women suffer a motherhood wage penalty, resulting in reduced pay relative to childless women. We use a unique dataset of all Israeli women who graduated college or university during the period 1995–2008 and their husbands to investigate whether the motherhood penalty is the result of a household decision. Thus, we investigate whether the wage gap between husband and wife before they have children affects the decision of which spouse will be the main provider and which will have the main responsibility for childrearing. We find that the couple’s initial wage ratio does not affect this decision, since a woman almost always bears the opportunity cost of childrearing even if she has a much higher starting wage than her husband.
Did capital replace labor? New evidence from offshoring
Authors: Choi Paul Moon Sub , Kim Kee Beom , Seo Jinyoung
Published: September 2018

Neoclassical theory explains the global decline of the labor income share by capital-labor substitution due to the affordable relative price of capital. Based on the Morishima elasticities of substitution among capital, labor disaggregated into high-, medium-, and low-skill groups, and imported and domestic intermediate inputs, offshoring appears to disproportionately affect job polarization globally and in developed economies. These findings in favor of the globalization hypothesis are buttressed by multivariate panel regressions. Lastly, offshoring might reinforce technological changes, a double-edged sword that can boost productivity growth but exacerbate wage inequality.
A novel method for site-specific chemical SUMOylation: SUMOylation of Hsp90 modulates co-chaperone binding in vitro
Authors: Wolmarans Annemarie , Kwantes Allison , LaPointe Paul
Published: September 2018

SUMO is covalently attached to lysine side chains in target proteins by the action of a cascade of E1, E2, and E3 ligases. Unlike ubiquitin, SUMO does not target proteins for degradation but rather plays a regulatory role in activating target proteins or directing them to multiprotein complexes. Isolating SUMOylated proteins from native sources is challenging because of the low stoichiometry of SUMOylation that occurs for any given target protein in cells. Here we report a novel strategy to couple SUMO to the site of a target lysine for the purpose of in vitro study. Introduction of a single cysteine after the C terminal diglycine motif and a cysteine in place of a target lysine in a substrate protein allows for efficient and specific crosslinking of SUMO using a homo-bifunctional maleimide crosslinker. We demonstrate that SUMO can be crosslinked in this manner to amino acid position 178 in the dimeric molecular chaperone, Hsp90. Chemically SUMOylated Hsp90 has very similar ATPase activity compared to unmodified Hsp90 but displays preferential co-chaperone binding in vivo. Our novel strategy can easily be applied to other SUMOylated or ubiquitinated target protein in vitro.
Selectivity Analysis for Networks Comprising Consecutive Reactions of Second and First Order
Authors: Murzin Dmitry Yu. , Simakova Irina L. , Wärnå Johan
Published: September 2018

Coupling of second and first order reactions in one pot fashion through a cascade process is an often encountered process. Consecutive reactions of this type are considered and selectivity analysis is performed demonstrating dependence of selectivity pattern on reaction parameters.
Noteworthy records and ecological niche modeling of the rare and endangered Goldman’s diminutive woodratNelsonia goldmani(Rodentia: Cricetidae) endemic to central Mexican highlands
Authors: León-Tapia M. Ángel , Cervantes Fernando A.
Published: September 2018

Nelsonia goldmaniis an uncommon rodent, endemic to highland microhabitats in central Mexico. Few individuals have been reported in scarce localities after being discovered in 1903 resulting in a lack of knowledge about its geographic distribution and actual presence in its habitat; such situation makes this species of national interest priority for conservation. Therefore, the aim of this study was to summarize collecting records, confirm the presence of this species in the field and estimate its ecological niche. We searched specimens in biological collections, carried out an ecological niche modeling (ENM) analysis and looked for individuals ofN. goldmaniin the field over a 2-year period. Our results identified only 43 specimens in biological collections, whose collecting localities had not been reported previously. The ENM analysis showed that the environmental suitability areas for this species are restricted and isolated with an apparent lack of environmental connectivity. Regarding fieldwork, we collected only five individuals in two localities. The possible environmental specificity and the lack of sampling focused on specific microhabitats could explain the low detection of the species thus far. Further research is needed to plan conservation actions to protect its populations.
Photonic welding points for arbitrary on-chip optical interconnects
Authors: Yu Zejie , Ma Yang , Sun Xiankai
Published: September 2018

Photonic integrated circuits (PICs) are an ideal platform for chip-scale computation and communication. To date, the integration density remains an outstanding problem that limits the further development of PIC-based photonic networks. Achieving low-loss waveguide routing with arbitrary configuration is crucial for both classical and quantum photonic applications. To manipulate light flows on a chip, the conventional wisdom relies on waveguide bends of large bending radii and adiabatic mode converters to avoid insertion losses from radiation leakage and modal mismatch, respectively. However, those structures usually occupy large footprints and thus reduce the integration density. To overcome this difficulty, this work presents a fundamentally new approach to turn light flows arbitrarily within an ultracompact footprint. A type of “photonic welding points” joining two waveguides of an arbitrary intersecting angle has been proposed and experimentally demonstrated. These devices with a footprint of less than 4 μm2 can operate in the telecommunication band over a bandwidth of at least 140 nm with an insertion loss of less than 0.5 dB. Their fabrication is compatible with photonic foundry processes and does not introduce additional steps beyond those needed for the waveguides. Therefore, they are suitable for the mass production of PICs and will enhance the integration density to the next level.
Genome as (hyper)text: From metaphor to theory
Authors: Zolyan Suren T. , Zhdanov Renad I.
Published: September 2018

The similarity between language and genetic information transmission processing has been recognized since molecular genetics was founded. Numerous attempts have been made to use linguistics techniques to decipher protein genes. The modest informational impact of various approaches to decoding the “protein language” was predictable: this type of technique is limited by the processes of encoding and at best helps compile a dictionary of units. However, this technique cannot describe a language and identify the semantic and textual structures that are decisive for communication. Thus, the functions of a large amount of non-coding DNA remain unclear. A text (but not a sign) should be regarded as an artefact of the creation, transmission, conservation and transformation of information. A general theory of text should be capable of describing linguistic texts and the process of their structuring, functioning and transformation. It should also be able to represent the biochemical structure of a genome as a hypertext that consists of an ordered subset of other texts. A text can be considered to be a quasi-organism that possesses memory, creative-cognitive characteristics and communicative force, and a cell can be considered as a quasi-intelligence capable of manipulating abstract semiotic entities. Such an approach requires the construction of a new, multimodal, and text-oriented version of semiotics (next-generation semiotics), in which text and context are the basic concepts and signs and meanings are considered to be context-dependent variables and, simultaneously, context-forming operators.
Muscle relaxant activities of pistagremic acid isolated from Pistacia integerrima
Authors: Rauf Abdur , Bawazeer Saud , Uddin Ghias , Siddiqui Bina S. , Khan Haroon , Ben Hadda Taibi , Mabkhot Yahia Nasser , Shaheen Usama , Ramadan Mohamed Fawzy
Published: September 2018

The aim of the current work was to explore the muscle relaxant effect of pistagremic acid (PA) isolated from Pistacia integerrima in various animal paradigms. In a rotarod test, PA caused a significant (p<0.05) muscle relaxant potential in a dose-dependent manner. When studied in the inclined plane test, pretreatment with PA (5 and 10 mg/kg) caused promising activity (p<0.05) after treatment for 30, 60 and 90 min. The muscle relaxant potential of PA was strongly complimented by the traction and chimney tests, showing a dominant effect after 60 min of treatment. In conclusion, PA possesses strong muscle relaxant activity in various animal-based models.
Relationships and Reliability Between a Drive Block Test and Traditional Football Performance Tests in High School Offensive Line Players
Authors: Collins Kyle S. , Coburn Jared W. , Galpin Andrew J. , Lockie Robert G.
Published: September 2018

Collins, KS, Coburn, JW, Galpin, AJ, and Lockie, RG. Relationships and reliability between a drive block test and traditional football performance tests in high school offensive line players. J Strength Cond Res 32(12): 3432–3441, 2018—The offensive line (OL) is a specialized football position responsible for blocking tasks. Little research exists on OL-specific movements and relationships to performance tests in high school players. This study investigated the reliability of the average and peak velocity (avgV, peakV) and momentum (avgM, peakM) of a drive block test (DBT) in 15 high school OL and relationships to performance tests. A linear position transducer attached to the OL waist measured the DBT from a 3-point stance into a blocking pad. Linear speed was measured by a 36.58-m sprint. Change-of-direction (COD) ability was measured by the pro-agility shuttle (first COD, second COD, and total time) and COD deficit from the first (COD deficit 1) and second COD (COD deficit 2) of the pro-agility shuttle. Vertical jump, standing broad jump (SBJ), and 1 repetition maximum (1RM) back squat were also measured. Pearson's correlations (p < 0.05) investigated relationships between the DBT and performance tests. Intraclass correlation coefficients (ICCs), dependent t-tests, and coefficient of variation (CV) assessed DBT reliability. Drive block test variables were reliable (ICC > 0.90; CV = 6.46–8.29%) and correlated with the second pro-agility shuttle COD and COD deficit 2 (r = −0.515 to −0.721). One repetition maximum back squat correlated with avgM and peakM (r = 0.551–0.582); SBJ correlated with avgV and peakV (r = 0.557–0.571). The pro-agility shuttle splits, COD deficit, and SBJ may provide useful information about DBT qualities important for high school OL. It is recommended high school OL training focus on strength, COD performance, and jumping ability to aid drive block performance.
Pre-exhaustion Exercise Differentially Influences Neuromuscular Fatigue Based on Habitual Physical Activity History
Authors: Harlan Kenneth G. , Merucci Roberto B. , Weaver Jalen J. , Windle Thomas C. , Malek Moh H.
Published: September 2018

Harlan, KG, Merucci, RB, Weaver, JJ, Windle, TC, and Malek, MH. Pre-exhaustion exercise differentially influences neuromuscular fatigue based on habitual physical activity history. J Strength Cond Res 35(3): 739–745, 2021—Although there is anecdotal evidence of a potential physiological benefit of pre-exhaustion exercise to enhance muscular recruitment, few studies have systematically examined the effect on neuromuscular activity. Moreover, a subject's habitual physical activity history may, in part, contribute to the muscle's response on a subsequent workbout after a single pre-exhaustion workbout. To date, no studies have examined the effect of pre-exhaustion exercise on the electromyographic fatigue threshold (EMGFT). The purpose of this study, therefore, is to determine whether pre-exhaustion exercise influences the EMGFT. Specifically, we were interested in determining whether or not there is a dichotomous response to pre-exhaustion exercise based on the individual's habitual physical activity history. Thus, we hypothesized that healthy active subjects would have reduced EMGFT values, whereas elite runners would have increased EMGFT values as a result of the pre-exhaustion exercise. Eight healthy college-aged men (mean ± SEM, age = 24.5 ± 0.3 years; body mass = 83.1 ± 3.0 kg; and height = 1.80 ± 0.02 m) and 9 elite runners (mean ± SEM, age = 23.4 ± 0.7 years; body mass = 70.3 ± 2.7 kg; and height = 1.79 ± 0.03 m) participated in current study. Each subject visited the laboratory on 2 occasions separated by 7 days and performed the single-leg knee-extensor ergometry test. For one of the visits, the subjects performed the Thorstensson test (50 continuous, concentric knee extensions) before the single-leg knee-extensor ergometry. The EMGFT was measured on both visits for all subjects. For healthy subjects, we found that the EMGFT was significantly reduced after performing the 50 isokinetic knee extensions (control: 27 ± 6 W vs. Thorstensson: 21 ± 6.0 W; p = 0.001), whereas for elite runners, there was no significant mean differences between the 2 visits (control: 38 ± 3 W vs. Thorstensson: 39 ± 2 W; p = 0.813). These results suggest that 50 repetition of isokinetic muscle action, as a method of pre-exhausting the quadriceps femoris muscles, may be influenced by the subject's habitual exercise history.
Muscle Activation During Power-Oriented Resistance Training: Continuous vs. Cluster Set Configurations
Authors: Morales-Artacho Antonio J. , García-Ramos Amador , Pérez-Castilla Alejandro , Padial Paulino , Gomez Angel M. , Peinado Antonio M. , Pérez-Córdoba Jose L. , Feriche Belén
Published: September 2018

Morales-Artacho, AJ, García-Ramos, A, Pérez-Castilla, A, Padial, P, Gomez, AM, Peinado, AM, Pérez-Córdoba, JL, and Feriche, B. Muscle activation during power-oriented resistance training: continuous vs. cluster set configurations. J Strength Cond Res 33(7S): S95–S102, 2019—This study examined performance and electromyography (EMG) changes during a power training protocol comprising continuous or clustered set configurations. Eighteen active males completed 6 sets of 6 repetitions during the loaded (20% 1 repetition maximum) countermovement jump (CMJ) exercise, continuously (n = 9) or with a 30-second pause every 2 repetitions (cluster; n = 9). Power output, vastus lateralis (VL), vastus medialis (VM), and rectus femoris (RF) EMG were recorded during all CMJs. Relative changes from the first repetition were assessed on the EMG root mean square (RMS), median frequency (Fmed), and a low- to high-frequency ratio index of fatigue (FInsmk). Greater power output decrements were observed during the continuous set configuration (p = 0.001,

JOURNAL/jscr/04.03/00124278-201907001-00011/inline-formula1/v/2023-08-19T002824Z/r/image-tiff

< 0.01). Greater RMS increments in VL (6.8 ± 11.3 vs. −1.7 ± 5.8%) and RF (9.3 ± 14.2 vs. 1.9 ± 6.9%), but not VM (2.0 ± 4.7 vs. 2.6 ± 7.3%), were also observed in the continuous compared with the cluster sets (p = 0.033,

JOURNAL/jscr/04.03/00124278-201907001-00011/inline-formula2/v/2023-08-19T002824Z/r/image-tiff

= 0.06). Progressive decrements in Fmed and increments in FInsmk were observed across repetitions in both set configurations. In conclusion, although clustering sets between repetitions clearly maintained power output, mixed responses were observed on the examined EMG parameters.
Use of Functional Movement Screen Scores to Predict Dynamic Balance in Physically Active Men and Women
Authors: Scudamore Eric M. , Stevens Sandra L. , Fuller Dana K. , Coons John M. , Morgan Don W.
Published: September 2018

Scudamore, EM, Stevens, SL, Fuller, DK, Coons, JM, and Morgan, DW. Use of functional movement screen scores to predict dynamic balance in physically active men and women. J Strength Cond Res 33(7): 1848–1854, 2019—The primary focus of this study was to determine whether scores obtained from the Functional Movement Screen (FMS) can predict dynamic balance in young, healthy adults. Thirty-four physically active participants completed the FMS, and balance was assessed using measures of composite reach (CR) distance and overall stability indices (OSI) derived from Y Balance and Biodex Balance System testing, respectively. Results indicated that higher overall FMS scores were associated with better CR and OSI, and participants with FMS composite scores greater than 14 exhibited better CR compared to those with composite scores less than or equal to 14. In addition, lasso penalized regression demonstrated that (a) scores of 2 on the deep squat and 3 on the trunk stability push-up movements predicted a greater CR and (b) higher shoulder mobility scores and a rotary stability score of 3 predicted better OSI. We conclude that dynamic balance in young, active men and women can be predicted by specific FMS item scores.
Body Composition Variables by Sport and Sport-Position in Elite Collegiate Athletes
Authors: Fields Jennifer B. , Merrigan Justin J. , White Jason B. , Jones Margaret T.
Published: September 2018

Fields, JB, Merrigan, JJ, White, JB, and Jones, MT. Body composition variables by sport and sport-position in elite collegiate athletes. J Strength Cond Res 32(11): 3153–3159, 2018—To assess body composition measures by sport and sport-position. Elite collegiate athletes participated (n = 475): men's and women's soccer (MSOC, n = 67; WSOC, n = 110); men's and women's swimming (MSWIM, n = 26; WSWIM, n = 22); men's and women's track and field (MTF, n = 29; WTF, n = 24); women's lacrosse and volleyball (WLAX, n = 84; WVB, n = 73); and baseball (BASE, n = 40). One-way analysis of variances assessed differences across sport and sport-position. Post hoc analysis was Tukey honestly significant difference (p ≤ 0.05). For men, BASE and MSWIM had the highest body fat percentage (BF%) (BASE: 16.3 ± 5.2%; MSWIM: 14.2 ± 3.5%). MSOC (11.5 ± 5.3%, 0.13 ± 0.72 kg) and MTF (9.8 ± 5.1%, 0.11 ± 0.08 kg) had the lowest BF% and fat mass (FM)-to-fat-free mass (FFM) ratio (FM:FFM). Fat mass did not differ between MSOC (9.1 ± 4.9 kg), MTF (7.7 ± 5.9 kg), and MSWIM (11.1 ± 3.1 kg). Fat mass for MSOC and MTF was lower than BASE (14.1 ± 5.2). For women, WVB displayed the highest BF% (25.4 ± 5.1%), FM (18.5 ± 5.2 kg), FFM (53.3 ± 5.1 kg), and body mass (BM) (71.8 ± 8.4 kg), but did not differ from WSWIM in BF%, FM, FFM, and BM. WTF had the lowest BF% (12.9 ± 4.0%), FM (7.5 ± 2.5 kg), BM (58.2 ± 4.4 kg), and FM:FFM (0.15 ± 0.05 kg). VB had the highest FFM (53.3 ± 5.1 kg). Body composition differences were observed between sport-positions (p < 0.01). Body composition differed across sport and sport-position, which may be attributed to sport-specific physiological demands.
Energy Investigation in Serpentine Heat Exchanger Using Aluminum Oxide Nanofluid on Solar Photovoltaic/Thermal System
Authors: Ramadass Geetha , Vijayalakshmi M. M. , Natarajan E.
Published: September 2018

A solar photovoltaic thermal system (SPV/T) is a hybrid technology that produces electrical power and thermal energy simultaneously with better overall performance. The objective of this study is to evaluate the effects of utilizing a nanofluid as one of the coolants in the performance of an SPV/T system. The working fluids considered in this evaluation of the system are pure water and aluminum oxide (Al2O3) nanoparticles of φ = 0.1 % and 0.2 % concentration in (w/v)%, mixed in milli-Q water as the base fluid. The study focuses on the heat transfer characteristics of working fluids through a serpentine flow copper tube heat exchanger in comparison with water. This experimental setup consists of an SPV/T system with 100 W capacity and a collector area of 0.914622 m2. For the flow supplied by the pump to the SPV/T system for the nanofluids with φ = 0.1 % and 0.2 % and water at mass flow rates of 0.015, 0.0133, and 0.0117 kg/s, the electrical (PV) efficiency for water was between 10.82 % and 11.06 %—for Al2O3 0.1 %, 12.19 %–13.13 %, and for Al2O3 0.2 %, 12.47 %–13.41 %. The thermal efficiency for water was between 53.61 % and 54.07 %; for Al2O3 0.1 %, it was 69.45 %–69.67 %, and for Al2O3 0.2 %, it was 70.76 %–71.02 %, respectively.
Superpave Design Aggregate Structure Considering Uncertainty: II. Evaluation of Trial Blends
Authors: Easa Said M.
Published: September 2018

The current evaluation of Superpave design aggregate structure is deterministic. The design involves evaluation of selected trial blends based on volumetric, compaction, and dust proportion requirements. This article incorporates the uncertainties of all 17 variables involved in the process, measured by the coefficient of variation (CV), and develops a revised procedure for comparing mixture properties with the performance-based criteria. The uncertainties of eight measured properties are propagated through the calculation and make the uncertainty of some variables very large. Issues related to the reliability of some variables (CV > 25 %) are discussed and criteria to resolve them are established. The developed mathematical formulas of uncertainty were verified using Monte Carlo simulation. The results show that the potentially unreliable variables are as follows: volume of absorbed asphalt, percentage of absorbed asphalt, and percent voids in total mix at the design compaction level. A tool is provided to help the designer trace the uncertainty of the unreliable variables back to the measured properties so that their precisions may be revised. The current National Cooperative Highway Research Program–recommended precisions for specific gravities were found to be generally satisfactory. However, further research should continue to improve the precision of specific gravity measurements as some intermediate variables may still become unreliable.
Predictive Model Markup Language (PMML) Representation of Bayesian Networks: An Application in Manufacturing
Authors: Nannapaneni Saideep , Narayanan Anantha , Ak Ronay , Lechevalier David , Sexton Thurston , Mahadevan Sankaran , Lee Yung-Tsun Tina
Published: September 2018

Bayesian networks (BNs) represent a promising approach for the aggregation of multiple uncertainty sources in manufacturing networks and other engineering systems for the purposes of uncertainty quantification, risk analysis, and quality control. A standardized representation for BN models will aid in their communication and exchange across the web. This article presents an extension to the predictive model markup language (PMML) standard for the representation of a BN, which may consist of discrete variables, continuous variables, or their combination. The PMML standard is based on extensible markup language (XML) and used for the representation of analytical models. The BN PMML representation is available in PMML v4.3 released by the Data Mining Group. We demonstrate the conversion of analytical models into the BN PMML representation, and the PMML representation of such models into analytical models, through a Python parser. The BNs obtained after parsing PMML representation can then be used to perform Bayesian inference. Finally, we illustrate the developed BN PMML schema for a welding process.
PATOLOGIA EM LAJES MACIÇAS: UM ESTUDO DE CASO EM UM EDIFÍCIO EMPRESARIAL
Authors: Da Costa Ronaldo Garcia , Da Silva Rebecca Alves , Domingues José Ricardo , De Farias Bruno Matos
Published: September 2018

Na elaboração de projetos arquitetônicos, particularmente em edificações, engenheiros e arquitetos defrontam-se com diversas alternativas de lajes. Constitui-se, pois, em uma importante decisão, pois poderá representar sensíveis resultados no custo e qualidade da edificação. O objetivo deste trabalho é apresentar as manifestações patológicas observadas em uma laje de cobertura de uma construção localizada no Rio de Janeiro.  A metodologia do estudo é uma pesquisa de campo. Como resultado, observou-se uma laje de concreto armado maciça, com idade próxima aos trinta anos, parcialmente coberta, revestida em sua parte superior por manta asfáltica e uma camada de argamassa, exposta às ações do tempo como intempéries e condições climáticas. Para a análise da estrutura foi realizada a inspeção visual da laje em estudo pela face superior onde as manifestações patológicas foram identificadas. Evidenciou-se que o programa de manutenção foi negligenciado, além da laje ter sido constituída por concreto insuficiente e cujo processo de execução também apresentou vícios construtivos.
Dynamics and Functional Role of Dopaminergic Neurons in the Ventral Tegmental Area during Itch Processing
Authors: Yuan Lei , Liang Tong-Yu , Deng Juan , Sun Yan-Gang
Published: September 2018

Itchiness triggers a strong urge to engage in scratching behavior, which could lead to severe skin or tissue damage in patients with chronic itch. This process is dynamically modulated. However, the neural mechanisms underlying itch modulation remain largely unknown. Here, we report that dopaminergic (DA) neurons in the ventral tegmental area (VTA) play a critical role in modulating itch-induced scratching behavior. We found that the activity of VTA DA neurons was increased during pruritogen-induced scratching behavior in freely moving male mice. Consistently, individual VTA DA neurons mainly exhibited elevated neural activity during itch-induced scratching behavior as demonstrated byin vivoextracellular recording. In behavioral experiments, the transient suppression of VTA DA neurons with the optogenetic approach shortened the pruritogen-induced scratching train. Furthermore, the DA projection from the VTA to the lateral shell of the nucleus accumbens exhibited strong activation as measured with fiber photometry during itch-elicited scratching behavior. These results revealed the dynamic activity of VTA DA neurons during itch processing and demonstrated the modulatory role of the DA system in itch-induced scratching behavior.

SIGNIFICANCE STATEMENTItchiness is an unpleasant sensation that evokes a scratching response for relief. However, the neural mechanism underlying the modulation of itch-evoked scratching in the brain remains elusive. Here, by combining fiber photometry, extracellular recording, and optogenetic manipulation, we show that the dopaminergic neurons in the ventral tegmental area play a modulatory role in itch-evoked scratching behavior. These results reveal a potential target for suppressing excessive scratching responses in patients with chronic itch.
MicroRNA-93 mediates cabergoline resistance by targeting ATG7 in prolactinoma
Authors: Wu Zerui , Cai Lin , Lu Jianglong , Wang Chengde , Guan Jiaqing , Chen Xianbin , Wu Jinsen , Zheng Weiming , Wu Zhebao , Li Qun , Su Zhipeng
Published: September 2018

To date, the management of dopamine agonist (DA)-resistant prolactinomas remains a major clinical problem. Previously, we determined that miRNA-93 expression increases in DA-resistant prolactinomas; however, the role of miRNA-93 in the DA resistance remains largely unexplored. Hence, this study aimed to investigate the susceptibility of tumor cells to cabergoline (CAB) and the autophagy changes in MMQ and GH3 cells after miRNA-93 overexpression or inhibition. We used bioinformatics to identify the potential target of miRNA-93. Subsequently, we analyzed the correlation between miRNA-93 and autophagy-related 7 (ATG7) using protein expression analysis and luciferase assays. Furthermore, the change in the effect of miRNA-93 was measured after ATG7 overexpression. miRNA-93 expression was elevated in DA-resistant prolactinomas, whereas the expression of its identified target, ATG7, was downregulated. miRNA-93 overexpression suppressed the cytotoxic effect of CAB in MMQ and GH3 cells. In contrast, miRNA-93 downregulation enhanced CAB efficiency and promoted cell autophagy, eventually resulting in apoptosis. These results were further confirmed in in vivo xenograft models in nude mice. ATG7 overexpression could reverse the inhibitory effect of miRNA-93 on CAB treatment. Taken together, our results suggest that miRNA-93 mediates CAB resistance via autophagy downregulation by targeting ATG7 and serves as a promising therapeutic target for prolactinoma.
Pengaruh Job Embeddedness Dan Work Engagement Terhadap Intensi Turnover
Authors: Lestari Ayu , Dewi Mulia Sari
Published: September 2018

Human resources is a major asset that can support the achievement of company objectives. Therefore, the company continually strives to develop and maintain employees in order not to affect the movement of employees (turnover). This study aims to examine the effect of job embeddedness and workengagement on turnover intention. These samples included 200 employees of PT Medco E & P Indonesia taken with nonprobability sampling technique. Test the validity of the instrument turnover intention, scale job embeddedness, and Utrecht Work Engagement Scale (Uwes) was done by using confirmatory factor analysis (CFA). Results of multiple regression analysis is that there is significant influence job embeddedness and work engagement against turnover intention with R = 0.43. There are two dimensions of job embeddedness of variables that provide significant and negative effect terhadapintensi turnover, the fit organization and sacrifice organization DOI: 10.15408/tazkiya.v20i2.9171
Impact Of Social Support, Psychological Capital, And Workplace Spirituality To Employee Engagement At Company
Authors: Herlina Alviyanti , Mujib Abdul
Published: September 2018

All companies expect their employees better in terms of work performance, able to adapt to changes inEmployee engagement, Social Support, Modal Psychologis, Workplace, Spiritualitythe working environment, able to adapt the organizational culture so that employees are able tocommit the company to achieve its goals. In other words, companies need a lot of employees are tiedto the company.This study was conducted to determine the effect of social support, psychologicalcapital, and workplace spirituality to the company's employee engagement. The total population of280 employees of PT Tunas Jaya Makmur Abadi and sampled 266 employees of production takenusing purposive sampling technique.The results showed that the four dimensions of social support (areal support, information support, emotional support, and implicit support) not significant effect onemployee engagement, three-dimensional psychological capital (self-efficacy, optimism, andresilience), two dimensions of workplace spirituality (inner life and belonging to a community) thatsignificantly influence employee engagement. Researchers hope the implications of this study can bereviewed and could be developed in future studies. For example, by adding other variables related toemployee engagement that may have a bigger impact on employee engagement. DOI: 10.15408/tazkiya.v22i1.8151
Studies Of Interpersonal Communication In Adolescents Seen Form The Aspect Of Selfconcept And Self Disclosure
Authors: Qudrotin Lilih , Mulyono Rachmat
Published: September 2018

This study was conducted to determine the dimensions of self concept (self image, selfevaluation, ideal-self, and social self) and self- disclosure (amount, valance, accuracy & honesty, intention, and intimacy) on communication interpersonal adolence. The samples used in this study are 284students in SMPN 1 Rajeg. This study used quantitative method with multiple regression analysis. The results of this study show that self-concept and selfdisclosure have significant influence on self adjustment of new immigrant students in college (R square = 17.6 %, sig = 0,000). The results of minor hypothesis testing show that ideal-self,amount, and valensi significantly influence communication interpersonal of students inSMPN 1 Rajeg. The implications of the findings in terms of providing interventions forincreasing levels of communication interpersonal among students in SMPN 1 Rajeg werediscussed. DOI: 10.15408/tazkiya.v22i1.8161
Pengaruh Variabel Terkait Email, Kepribadian Dan Demografi Terhadap Stres Kerja
Authors: Aini Nurul , Nisa Yunita Faela
Published: September 2018

This study was conducted to determine the significance of the influence of related variables email (the email work importance, email volume, email management tactics, email overload), type D personality and demographics (gender, occupation, age) against work stress. Participants in this study were employees who use email as a medium job taken with non- probability sampling technique that is convenience sampling. CFA Technique (Confirmatory Factor Analysis) was used to test the validity of measuring instruments and multiple regression analysis was used to test the research hypothesis.This research showed that is significantly related variables email, type D personality, anddemographics (gender, occupation and age) as an influence on work stress. A large proportion of thevariance of work stress described by all independent variables by 46.4%, while the remaining 53.6% isinfluenced by other variables outside of this study. There are three variables that significantly to jobstress, type D personality, gender and occupation. While the variable related to email (email workimportance, email volume, email management tactics, email overload), and age did not significantlyinfluence work stress. Researchers suggest the company should have the data of employees who havepersonality type D, in order to minimize the stress of work on employees. DOI: 10.15408/tazkiya.v22i1.8163
Feminismo e o anarquismo pelas bordas: a resistência enquanto ação política
Authors: Dell'Aglio Daniela Dalbosco , Machado Paula Sandrine
Published: September 2018

Esse artigo coloca em questão o conceito de resistência para pensar o feminismo anarquista, anarca-feminismo, ou ainda, as políticas queer, e os modos de fazer política que consideramos que escapam do esperado, não percorrem caminhos institucionais e que utilizam estratégias fora do alcance do Estado. A partir de conceitos que envolvem a analítica de poder, do Foucault, compreendemos como o Estado está imbricado nas construções dos modos de vida, opressões e hierarquias. A partir desta análise, abordaremos o anarquismo enquanto uma estratégia atrelada à resistência, que deve ser compreendida enquanto uma prática de liberdade e, ainda, enquanto uma forma de rejeição da tutoria e autoridade que controlam as subjetividades.
As bases da nova direita: estudo de caso do Movimento Brasil Livre na cidade de São Paulo
Authors: Duda da Silva Ederson
Published: September 2018

O presente artigo é o resultado de pesquisas bibliográficas e de observação de campo realizada durante as manifestações em favor do impedimento de Dilma Rousseff. A finalidade deste artigo é compreender a formação de um movimento social de direita no Brasil, analisando os processos e as mudanças estruturais que impulsionaram a atuação do que veio a ser denominado como “nova direita”. Para tal, utilizaremos os conceitos de repertório e performance de Charles Tilly. Entendemos que o que caracteriza esta nova direita hoje é a inovação em sua ação política, passando a assimilar novas táticas ao seu repertório patriota, como protestos de rua. Estudaremos especificamente o Movimento Brasil Livre (MBL), grupo que se destacou durante os protestos pró-impeachment, investigando sua atuação entre 2013 a 2016, resgatando o cenário em qual surgiu e se fortaleceu.
Dinâmicas contemporâneas das mobilizações sociais
Authors: Espíndula Brenda , Silva Camila Farias da , Rech Carla Michele , Silva Marcelo Kunrath da
Published: September 2018

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Checklist of medium-sized to large mammals of Campos Gerais National Park, Paraná, Brazil
Authors: Pereira Alan Deivid , Bazilio Sergio , Orsi Mário Luís
Published: September 2018

Campos Gerais National Park lies within the Brazilian Atlantic Rainforest, a biodiversity hotspot and a priority for conservation. Current analysis, featuring a list of large and medium-sized mammal species in the park, was conducted between July 2013 and July 2014 and between May 2016 and April 2017. With a 780-hour sampling effort in active research and 157,516 hours in camera traps, 31 species of 17 families and 8 orders were recorded. Furthermore, 42% of recorded mammals in the park proved to be endangered species at state, national, or international levels. Two exotic and 1 domestic species were reported in the park. Results contribute towards an in-depth knowledge of the fauna in south Brazil and may help in further research work and management, complying with conservation proposals in the biodiversity of the Campos Gerais region in the state of Paraná, Brazil.
PENGARUH WARNA WADAH PADA PERTUMBUHAN DAN PERKEMBANGAN LARVA IKAN RAINBOW KURUMOI (Melanotaenia parva)
Authors: Rahmawati Riani , Tutik Kadarini Tutik Kadarini
Published: September 2018

Rainbow kurumoi (Melanotaenia parva) merupakan salah satu ikan endemik Indonesia yang berasal dari Danau Kurumoi, Papua. Ikan ini merupakan salah satu komoditas potensial untuk perdagangan ikan hias. Akan tetapi, pemenuhan permintaan ikan rainbow masih mengandalkan hasil tangkapan alam. Rekayasa lingkungan diperlukan untuk meningkatkan produksi ikan rainbow ini. Penelitian ini bertujuan untuk mengetahui warna wadah yang sesuai untuk optimalisasi pemeliharaan larva ikan rainbow kurumoi. Perlakuan dalam penelitian ini adalah: A) warna wadah merah; B) warna wadah biru; dan C) warna wadah hijau. Larva dipelihara dalam wadah volume 4 L dengan kepadatan 20 ekor/L selama 28 hari. Pakan yang diberikan berupa infusoria, Rotifer, Artemia, dan Moina secara bertahap dengan metode ad libitum. Hasil penelitian menunjukkan bahwa larva yang diberikan perlakuan beda warna wadah tidak berbeda nyata (P>0,05) terhadap pertumbuhan dan sintasan. Perlakuan A (warna wadah merah) menunjukkan laju pertumbuhan spesifik panjang tertinggi yaitu sebesar 2,2 ± 0,1%/hari; dilanjutkan perlakuan B (2,1 ± 0,7%/hari); dan terakhir perlakun C (1,8 ± 0,7%/hari). Untuk laju pertumbuhan spesifik berat pada perlakuan A sebesar 6,7 ± 1,2%/hari; diikuti perlakuan C (6,4 ± 0,3%/hari) dan perlakuan B (5,5 ± 1,6%/hari). Perkembangan sirip sudah lengkap pada umur 27 hari setelah menetas dengan panjang total tubuh (TL) berkisar antara 8,0-8,6 mm.Rainbow kurumoi (Melanotaenia parva) is one of endemic fish from Kurumoi Lake, Papua, Indonesia. The fish is considered one of the potential commodities in the ornamental fish market. However, to supply the demand for rainbow fish still relies on wild capture. Environmental manipulation is needed to improve the production of rainbow fish. The aim of this study was to evaluate the effects of tank color on the growth of kurumoi rainbow larvae. The treatments in this study were: A) red; B) blue; and C) green tanks. The larvae were reared in the 4 L volume tanks with a density of 20 ind./L for 28 days. The larvae were fed, in stages, with infusoria, Rotifer, Artemia, and Moina with ad libitum method. The results showed that the red tank (A) had the highest specific growth rate of length (2.2 ± 0.1%/day) followed by blue (B) (2.1 ± 0.7%/day) and green (C) (1.8 ± 0.7%/day) tanks. The red tank (A) had the highest specific weight growth rate (6.9 ± 1.2%/day) followed by the green (C) (6.4 ± 0.3%/day) and the lowest was blue (B) (5.5± 1.6%/day) tanks. The larvae maintained in the red tanks showed brighter color than that of the other two tanks. The fins development has completed on 27 days after hatching (8.0-8.6 mm TL) [ FOR WHICH TANK]. This research indicates that the tank colors do not have any influence on the growth and survival (P>0.05) of rainbow kurumoi larvae.
DAYA DUKUNG EKOLOGI UNTUK BUDIDAYA IKAN KAKAP DALAM KERAMBA JARING APUNG, STUDI KASUS DI PERAIRAN BIAK-NUMFOR
Authors: Andayani Ariani , Hadie Wartono , Sugama Ketut
Published: September 2018

Kabupaten Biak-Numfor merupakan salah satu lokasi yang ditetapkan sebagai Sentra Kelautan dan Perikanan Terpadu (SKPT), yang memiliki potensi untuk pengembangan budidaya laut, sehingga perlu dilakukan kajian kesesuaian lokasi dan daya dukung lingkungannya. Penelitian ini bertujuan untuk mengkaji kesesuaian perairan dan estimasi daya dukung lingkungan (ekologi) untuk pengembangan budidaya ikan kakap (Lates calcarifer). Kajian ini dilakukan di dua lokasi yaitu Pulau Nusi dan Teluk Urfu. Pengumpulan data primer dilakukan melalui survai lapangan dan pengumpulan data sekunder melalui Dinas terkait. Data survai lapangan yang dikumpulkan meliputi: arus, kedalaman, pH, suhu, salinitas, dissoloved oxygen (DO), amonia, nitrit, nitrat, fosfat, total suspended solid (TSS), dan kecerahan. Data sekunder yang dikumpulkan antara lain: Peta RBI dan data spasial dari Rencana Zonasi Wilayah Pesisir dan Pulau-Pulau Kecil RZWP3K Kabupaten Biak-Numfor 2015. Analisis kesesuaian perairan dilakukan dengan perangkat lunak Quantum GIS (QGIS). Analisis spasial berbasis raster. Hasil analisis kesesuaian perairan untuk budidaya ikan kakap dalam keramba jaring apung (KJA), di sekitar Pulau Nusi memiliki potensi yang sesuai seluas 324,11 ha dari total area seluas 2.643 ha, sedangkan di Teluk Urfu area yang sesuai seluas 0,247 ha dari total area 33 ha. Hasil perhitungan daya dukung ekologi, Teluk Urfu tidak direkomendasikan adanya kegiatan budidaya ikan, kenyataannya saat ini telah terpasang 12 lubang KJA. Sedangkan di Pulau Nusi potensi pengembangan budidaya laut khususnya ikan kakap cukup luas. Daya dukung ekologinya adalah 158 lubang KJA (3 m x 3 m x 3 m) dengan terget panen per lubang adalah 175 kg.Biak-Numfor Regency has been designated as one of the locations of Integrated Marine and Fisheries Center (SKPT). The region has the potential to be developed as mariculture area. Thus, it is necessary to determine the site suitability and calculate the environmental carrying capacity of the area for mariculture development. This study aimed to assess the site suitability and estimate the environmental carrying capacity (ecology) of the region waters for Asian seabass/barramundi (Lates calcarifer) mariculture. The study was carried out in two locations: Nusi Island and Urfu Bay. Primary data were collected from a field survey and secondary data was gathered from the local fisheries extension office in Biak