bluuebunny/crossref_metadata_2025 huggingface dataset:
Using Synthetic Biological Approaches to Solve Yellow Water Wastage Problems
Authors: Liu Runlin , Chen Jun
Published: January 2025

This project is focused on engineering the pET-32(a) vector to insert the CDS region, enabling the expression of TAG lipase in E. coli BL21 (DE3). The primary objective is to produce TAG lipase in large quantities, which can then be used to catalyze the esterification of alcohols and organic acids present in yellow water, converting them into ester flavor compounds. This conversion process aims to reduce waste and enhance the flavor profile of fermented products. The project employs benching software to accurately manipulate the pET-32(a) vector in the intended insertion and expression of the target gene. In this way, through the improved generation of TAG lipase, it provides a green solution to the yellow water waste issue in Baijiu production and also has a wide application in the field of aroma improvement and waste minimization in the fermentation industry.
The Impact of Different Fertilization Methods on Soil Heavy Metal Pollution and Restoration Methods
Authors: Cai Yantong
Published: January 2025

Soil heavy metal contamination, exacerbated by the long-term use of phosphate and organic fertilizers, poses a significant threat to agriculture and global ecosystems. Accumulation of heavy metals such as arsenic (As), cadmium (Cd), lead (Pb), and mercury (Hg) in soils can endanger human health and ecosystem services. This paper evaluates the content of heavy metals in various fertilizers and reviews existing remediation technologies. Among these, plant-microbe collaborative remediation shows promise for mitigating heavy metal pollution, although its effectiveness in multi-pollutant environments remains underexplored. Current research reveals a gap between laboratory results and practical applications, with limited studies on long-term ecological impacts. Future research should prioritize addressing complex pollution scenarios and developing efficient, eco-friendly remediation strategies to promote sustainable agriculture and environmental protection
Using CRISPR/Cas9 Technology to Target TP53 Related Cancers
Authors: Hsieh Man Ho Damien
Published: January 2025

Tumor protein 53 (TP53) is a tumor repressor gene that is highly responsible for activating cell cycle arrest in the event of DNA damage, stopping the replication of damaged cells, which may cause cancer. However, when mutated, TP53 is an oncogene, with mutated variants of it being seen in over half of all cancers diagnosed including the aforementioned four. With groundbreaking CRISPR-Cas9 gene editing technology coming to the forefront of biotechnological research, the applications to cancer research and gene therapy have been increasing. This review explores CRISPR-Cas9 and its uses for treatment and medication investigation in various cancers, including lung, prostate, breast, and bone cancer through the lens of the TP53 gene. Due to TP53s commonality in cancer, CRISPR-Cas9 gene editing technology can be used to its maximum potential in this context as a treatment or investigative tool, with it yielding positive results in reverting tumor growth, as well as great versatility when it comes to screening related genes that inhibit or encourage tumor growth which can be targeted by drugs, or even the screening of the drugs effectiveness themselves. Thus, CRISPR-Cas9s applications in TP53-related cancer treatment and chemotherapeutic fields prove this technology to be successful.
Research Progress and Future Development Directions of Alzheimers Disease
Authors: Jin Juan
Published: January 2025

Alzheimer's disease (AD) is a neurodegenerative disorder marked by the deterioration of neuronal cells, resulting in dementia and a reduction in cognitive abilities and autonomy in daily tasks. AD is a multifactorial disease impacted by numerous factors, including the cholinergic and amyloid hypotheses, advancing age, genetic predispositions, head trauma, vascular disorders, infections, and environmental influences. Present therapies, such as cholinesterase inhibitors and N-methyl-D-aspartate (NMDA) receptor antagonists, merely offer symptomatic alleviation without altering the advancement of the disease. Despite decades of research, no curative treatments exist, and numerous clinical trials have failed to demonstrate significant improvements in disease progression. While recent advancements, including the evaluation of drugs like aducanumab, offer hope, the journey toward effective disease-modifying therapies remains ongoing. This review discusses the current state of available treatments, the challenges they face, and future research directions aimed at developing disease-modifying therapies (DMTs) that target abnormal tau protein metabolism, -amyloid accumulation, inflammatory responses, and other underlying mechanisms.
Circadian rhythms and depression: A review of mechanisms, effects and treatment strategies
Authors: Angqin Talin
Published: January 2025

Circadian rhythms play an important role in the temporal co-ordination of many physiological processes such as the sleep-wake cycle, hormone release or metabolism. Major depressive disorder is associated with severe disruption of these rhythms. This review discusses the basic functions of circadian rhythms and how they control various physiological systems and maintain homeostasis in the body. It also explores epidemiological data linking circadian rhythm disruptions such as insomnia, jet lag, and shift work to a high risk of depression. The review also notes that circadian rhythm disruption can exacerbate depression, reduce treatment response, and lead to more frequent relapses. The review identifies treatments such as phototherapy, melatonin supplements, and sleep stage interventions as potential strategies for restoring circadian rhythm function in patients with depression, thereby improving clinical care. The aim of this review is to provide direction for future research and development of circadian rhythm-based treatments for depression.
Exploring the Relationship Between Fiscal Policy and the Technological Innovation Ability of New Energy Enterprises
Authors: Shi Yi
Published: January 2025

Faced with unprecedented changes, the emergent energy sector has evolved the new high ground of international competition, among which the development of the new energy vehicle industry is particularly crucial and of great significance to the global energy transformation. To strengthen the role of fiscal policy in promoting innovation in new energy technologies, this article has introduced a sequence of fiscal policies to promote the development of high-tech, while using tax incentives and subsidies to guide new energy enterprises to increase their research and development efforts and achieve technological innovation. This article takes the strategic emerging industry represented by the new energy vehicle industry as an example, analyzes the role and constraint mechanism of fiscal policy on enterprise innovation, explores how fiscal policy affects the technological innovation capability of new energy enterprises, and analyzes the differentiated impact of fiscal policy on different new energy enterprises. Finally, this article proposes strategic recommendations for coordinating fiscal policies to promote innovation in strategic emerging industry enterprises, which has practical significance for the development of China's strategic emerging industries
Research on the Competitive Development and Prospects of Nvidia
Authors: Wang Jinchuan
Published: January 2025

With the rapid development of technologies such as artificial intelligence (AI), deep learning and high performance computing (HPC), Nvidia has gradually become the technology company with the upper hand in the world in the last decade with its technical advantages in the graphics processing unit (GPU) field. The purpose of this article is to analyze the future development prospects of Nvidia and explore its competition and challenges in the AI and GPU markets. Through the review and analysis of existing literature, combined with NVIDIA's financial data, SWOT analysis and industry environment assessment, the main opportunities and threats facing the company are revealed. The research shows that despite Nvidia's dominant position in GPU technology and AI, its future growth faces challenges from different aspects, including competitive pressure in the core market (GPU), bottlenecks in technological progress, saturation of the gaming graphics card market, and supply chain risks. The conclusion is that Nvidia's long-term growth prospects remain strong, especially in high-potential areas such as artificial intelligence and autonomous driving. However, with the rise of competitors such as AMD and Intel, as well as uncertainties in the global economy and supply chain, Nvidia will face fierce market competition. Therefore, Nvidia should continue to increase its technological innovation efforts, optimize supply chain management, and strengthen its strategic positioning in new technology areas. Nvidia may encounter many challenges in the next few years, but relying on its strong technological innovation capabilities, extensive market applications and strategic layout, it still has huge development potential
The Impact of Argentina's Fiscal Policy on Its Economy after the Foreign Debt Crisis and Its Implications for Other Developing Countries
Authors: Yang Zili
Published: January 2025

After experiencing the foreign debt crisis in the early 21st century, Argentina's overall economic downward trend is obvious. During the Kirchner government from 2003 to 2015, the Kirchners switched from using economic recovery to gain public support to using welfare, which eventually led to a high debt. The Macri government from 2016 to 2019 actively promoted trade liberalization and opened financial and capital markets by rebuilding the free market mechanism. In the end, the reform failed due to the public's distrust of the government and the central bank and the withdrawal of foreign capital. The excessive money issuance of the Fernandez government from the end of 2019 to the end of 2023 seems to have become the last straw that overwhelmed the Argentine economy. Despite the replacement of several governments, Argentina has been slow to get out of the predicament of inflation and the difficulty of developing its economy. The reason is that Argentina's domestic industry is backward and lacks refined control over foreign exchange, and its government cannot completely gain the trust of the people. In the short term, it is difficult for Argentina to break the current deadlock
The Impact of Green Trade Barriers on Developing Countries Exports and Policy Responses Taking Chinas Export of Agricultural Products as an Example
Authors: Zhang Yifan
Published: January 2025

The paper examines the significance and implications of green trade barriers, particularly in the aftermath of the 2008 Global Financial Crisis, during which protectionism tendencies among developed countries were intensified. It focuses on how these barriers affect international trade, with a particular emphasis on agricultural exports, especially for developing nations such as China. The study highlights the challenges faced by Chinese agricultural enterprises in adapting to strict international environmental standards, resulting in increased operational costs and reduced competitiveness in global markets. Findings reveal that while green trade barriers aim to promote environmental protection, they may inadvertently hinder the export capabilities of developing countries, thereby reducing market share. The paper proposes several recommendations, including the need for governments to establish stringent but fair environmental regulations that align with international standards, provide financial support for green innovation, and actively engage in multilateral trade negotiations to create consistent environmental requirements. It also underscores the importance for enterprises to adopt sustainable practices and diversify their market strategies to mitigate the adverse effects of these trade barriers
Research on the Development of New Energy Vehicle Industry from the Perspective of ESG
Authors: Tian Enhui
Published: January 2025

Against the backdrop of increasingly prominent global environmental issues, the importance of ESG concepts is becoming more apparent. The new energy vehicle industry is thriving due to its crucial role in addressing climate change. This article believes that the new energy vehicle industry is making significant progress in the environmental dimension. In the production process, enterprises actively adopt energy-saving and pollution-reduction measures to reduce their impact on the environment. In terms of usage, new energy vehicles become an important force in promoting green travel due to their efficient and clean characteristics; In the recycling process, the potential for the recycling and utilization of new energy vehicle batteries is enormous, providing strong support for the advancement of the circular economy. These efforts promote the green and circular development of the new energy vehicle industry. At the level of social responsibility, the new energy vehicle industry focuses on safeguarding employee rights, optimizing consumer services, and actively engaging in public welfare undertakings, which effectively promotes employment and environmental awareness. In terms of corporate governance, the internal structure of the enterprise continues to be optimized, risk management is effective compliant operations are good, and information disclosure is proactive. Furthermore, ESG performance exhibits a notable positive influence on corporate innovation outcomes, the stability of supply chains, as well as financial performance
A Study on the Historical Roots and Coping Strategies of Argentina's External Debt Crisis
Authors: Wu Hao
Published: January 2025

At present, the scale and impact of the external debt crisis in debt-troubled countries worldwide have gradually become the focus of international attention. Among them, Argentina's external debt crisis has become a widely discussed economic issue due to its severity and recurrence. This paper combs and studies the 2001 Argentine external debt crisis, analyzes in detail the historical roots and current situation of the crisis, and proposes corresponding solutions based on this. First, this paper combines domestic and international backgrounds to discover the imbalanced economic structure, imperfect financial system, and structural problems in fiscal policy and debt implied by the external debt crisis. Secondly, this paper analyzes the details and impact of the 2001 external debt crisis from the perspective of debt scale, debt structure, and debt restructuring. Finally, based on the historical roots and details of that crisis, a coping strategy with debt optimization as the premise and economic reform as the core is proposed. This study not only helps to deepen the understanding of the Argentine external debt crisis but also provides important guidance for debt-troubled countries worldwide to deal with external debt crises
Using SWOT Analysis to Assist Chinese Enterprises in Establishing Green Supply Chain Management
Authors: Feng Ziqi
Published: January 2025

Green Supply Chain Management (GSCM) is an innovative management approach that integrates environmental protection and resource efficiency into supply chain management, playing a significant role in enhancing the greening level of supply chains and achieving sustainable development. By reviewing the origins, development, and current state of GSCM, this paper highlights that, compared to developed countries such as those in Europe, the United States, and Japan, Chinese enterprises still have a substantial gap in establishing green supply chain management. SWOT analysis is a widely used tool in strategic planning and decision-making processes. By systematically assessing the strengths, weaknesses, opportunities, and threats of a project, enterprise, or industry, it helps decision-makers comprehensively understand both internal and external environments, enabling them to formulate more scientifically sound strategies. This paper aims to use the SWOT analysis framework and specific case studies to help enterprises thoroughly assess internal and external environmental factors in the process of implementing GSCM. It also provides strategic recommendations, offering theoretical support and practical references to aid Chinese enterprises in making informed decisions on establishing green supply chain management
The Driving Force for Sustaining Future Competencies for University Students in the Digital Era: Learning Strategies
Authors: Zheng Jie , Kim Kyu Tae
Published: January 2025

This study explores how learning strategies act as key drivers in strengthening sustainable competencies among university students in the digital age. As issues such as misinformation, cyberbullying, and online fraud increasingly threaten personal and societal well-being, digital literacy has become a critical competency. Learning strategies, particularly metacognitive self-regulation and resource management, play a crucial role in enhancing digital literacy by facilitating the critical evaluation of information and ethical decision-making. These strategies interact with digital literacy to foster core competencies—encompassing cognitive, emotional, and social abilities—which enable students to navigate complex digital environments responsibly and ethically. In this way, students not only enhance their capacity for critical thinking and problem-solving but also contribute to societal progress and pursue personal well-being in an increasingly digital world. This study employs a quantitative research design, using surveys with university students and random sampling to examine the relationship between learning strategies and digital literacy. The findings reveal that while cognitive strategies alone had limited effects, metacognitive self-regulation and resource management strategies were essential in translating digital literacy into practical skills. These skills empower students to critically assess information, identify credible sources, and navigate ethical challenges in both academic and real-world contexts. The results underscore the importance of embedding targeted learning strategies, particularly metacognitive self-regulation and resource management, within educational frameworks. These strategies help cultivate resilient, responsible digital citizens who are capable of addressing the ethical and practical challenges posed by the digital era. By equipping students with the necessary tools to engage responsibly and ethically in digital spaces, higher education institutions can foster the development of autonomous, reflective learners prepared for the complexities of the digital world.
Vendor Seleection in E-Commerce Using the Analytical Hierarchy Process Method
Authors: Yosiyanto Robi , Handayani Sri , Rahardjo Sri , Ricardianto Prasadja , Indrawan Rully , Fachrial Peppy
Published: January 2025

The development of the e-commerce business is an opportunity for logistics service providers as third parties who deliver goods sold by the seller to the location intended by the buyer. This study aims to analyze the behavior of fashion e-commerce customers in choosing the best vendor. Data were collected by in-depth interviews with five selected informants for vendor criteria and sub-criteria, then a survey was conducted on 100 respondents. The data were analyzed using the Analytical Hierarchy Process method to determine criteria and sub-criteria in selecting the preferred vendor. The first criterion was reliability of delivery, with the sub-criteria of timeliness, accuracy of delivery destination, and security of the condition of the goods. The second criterion was price. The next criterion was products with regular delivery, express, and same-day sub-criteria. The last criterion was shipping features with its sub-criteria shipping tracking, wide delivery area, and customer service. For the case of Indonesia in this study, the best vendor in delivering products from e-commerce to customers is obtained by Si Cepat in the first place, followed by J&T and JNE in second and third places.
Keputusan Konsumen Menggunakan Maskapai Penerbangan di Indonesia
Authors: Tatiana Yana , Sihombing Theresia Glory Sarce , Adi Erman Noor , Majid Suharto Abdul , Ichwan Gema Akbar
Published: January 2025

The main problem of the research is the lack of security system and the low level of trust that could affect the decision to use an airline. The purpose of the study is to analyze the security, safety and trust variables directly on passengers’ decision to use Garuda Indonesia airline. This study used a multiple linear regression approach with validity, reliability, t-test, F-test and hypothesis testing. The research sample was 80 respondents taken from Garuda Indonesia flight service users in Soekarno-Hatta International Airport. The key findings of this study are the safety and trust variables directly have a positive effect on the passengers’ decision, while the safety variable does not have a positive effect on the passengers’ decision to use Garuda Indonesia airline.
Multi Atribut Model Fishbein pada Ojek Online di Kabupaten Lombok Timur
Authors: Ruslin Ruslin , Ramli Chairul Aly , Supiarmo M Gunawan , Faqihi Ahmad , Ma'ruf M , Prayogi Galih Rio , Hermansyah Hermansyah , Langit Wahyu Gutama Detha Sekar
Published: January 2025

The main objective of this research is to analyze customer preferences of online motorcycle services in East Lombok using the Fishbein multi-attribute model. A deep understanding of the attributes most valued by customers is essential for service providers and local government to improve service quality of the community's needs. The research was conducted using purposive sampling with data collected over three months through interviews, questionnaires, observations, and literature reviews. The results indicate that all evaluation importance levels is categorized as important, with the highest score of 4.24 attributed to the safety and comfort attributes. On the other hand, the evaluation of belief levels (bi) falls into the good category, with the highest score of 3.83 attributed to driver experience. Based on the customers’ attitude analysis, several attributes receive positive scores: the safety and comfort attributes receive the highest attitude score of 15.94, followed by the driver’s experience attribute with a score of 15.87, and finally the ease of use of the online motorcycle application with a score of 15.61. In conclusion, deeper understanding of customers’ preferences could assist service providers and local government to improve the quality of online motorcycle services in East Lombok Regency.
Zona Bahaya Di Jalan Raya: Analisis Mendalam Kecelakaan Lalu Lintas di Jalur Bontang-Samarinda
Authors: Zainul L.M , Abdisa Hapnal , Maslina Maslina , Hardiyono Hardiyono , Rusba Komeyni , Nurhidayati Wa Ode
Published: January 2025

This study examines the characteristics of traffic accidents on Bontang-Samarinda route during the period of 2018-2020 to identify the accident patterns, causal factors, and accident-prone locations. The data were collected from the police records including time of occurrence, type of casualty, type of vehicle, type of collision, and causal factors. The analysis shows that accidents tend to occur in the afternoon and evening, with a pre-dominance of accidents involving two-wheeled vehicles. The most common type of casualty was minor injuries, but there was an increase in cases of serious injuries in 2020. The main contributing factors were high-speed and road marking violations, with straights and turns being common maneuver. Most crashes occurred in certain segments, especially at KM 22-28 and KM 64-70. This research methods is EAN weighting. The study concludes that prevention efforts should focus on the speed regulation, the driver awareness, and the infrastructure improvement in high-risk road segment. These results provide important guidance for policy makers and relevant authorities to develop more effective road safety strategies on Bontang-Samarinda route.
CONFLITOS FUNDIÁRIOS URBANOS:
Authors: Mota Andrea Bezerra de Melo Girão , Lemos Rafael Diogo Diógenes , Tassigny Mônica Mota
Published: January 2025

Neste trabalho, serão estudadas as raízes e os contornos jurídicos dos conflitos fundiários urbanos no Brasil e os métodos utilizados para sua solução. Busca-se averiguar se o ordenamento jurídico brasileiro tem instrumentos efetivos para a solução destes conflitos e se o Poder Judiciário está apto para aplicá-los, de forma a solucionar estes conflitos. Para isso, serão analisados, como exemplos de atuação do Poder Judiciário, dois processos judiciais que têm como questão subjacente ocupação de índios da tribo Kaingang no Município de Londrina, no Estado do Paraná, em que serão apreciados os instrumentos processuais e extraprocessuais tomados para a solução deste conflito fundiário. A pesquisa foi realizada a partir do método de abordagem dedutivo e a natureza foi teórica. O objetivo foi explicativo e, quanto ao objeto, a pesquisa foi bibliográfica e documental, com abordagem qualitativa
TECNOLOGIAS VESTÍVEIS E SUPERÁVIT COMPORTAMENTAL
Authors: Arantes Tobbin Raissa , Silva Galdino Cardin Valeria
Published: January 2025

O presente trabalho tem por objetivo analisar a utilização das tecnologias vestíveis no meio ambiente de trabalho e as consequências aos direitos da personalidade do trabalhador, especialmente à privacidade e ao direito à proteção de dados. Como resultado, a pesquisa verificou que os wearables, que coletam dados sobre saúde, são dispositivos que permitem o acesso a um superávit comportamental do trabalhador, representando técnica invasiva de privacidade no cenário do capitalismo de vigilância, especialmente quando utilizados para aferir produtividade, desempenho e incentivar o engajamento em tarefas por meio de gamificação, sendo essencial a tutela do direito à proteção de dados e da autodeterminação informativa do trabalhador, sob pena de imposição de comportamento e enrijecimento/tolhimento da personalidade. O artigo utilizou o método hipotético-dedutivo, fundamentado em pesquisa e revisão bibliográfica de obras, artigos de periódicos, legislação e doutrina aplicável ao tema.
A EMENDA CONSTITUCIONAL. N. 87/2015 E O DIFERENCIAL DE ALÍQUOTA DO ICMS:
Authors: Campos da Silva Maria Stela , Fraiha Pegado Daniel , Da Fonseca Pereira Luiz Felipe
Published: January 2025

A Emenda Constitucional n. 87/2015 provocou significativas alterações na sistemática de incidência do diferencial de alíquotas do ICMS. Contudo, alguns atos normativos ao tratarem da mudança constitucional acabaram por revelar lógicas distintas às operações e às prestações interestaduais de bens e serviços de transporte e de comunicação, destinados a consumidores finais não contribuintes do ICMS, localizados no Estado do Pará. Nesse sentido, à luz do construtivismo lógico-semântico, serão analisadas as incompatibilidades normativas veiculadas nas disposições do Convênio CONFAZ n. 93/2015 e na Lei Estadual n. 8.315/2015, que ensejam grave insegurança jurídica aos sujeitos integrantes dessa relação jurídico-tributária.
EXECUTAR OU NÃO EXECUTAR?
Authors: Capucho Pablo Henrique Paschoal , Amâncio Vieira Saulo Fabiano , Tieko Suguihiro Vera Lucia
Published: January 2025

O objetivo deste artigo é apurar o custo mínimo da execução fiscal na gerência de execução fiscal no município de Londrina/PR com a finalidade de estabelecer uma política tributária que considere o custo-benefício do ajuizamento de executivos fiscais, para que seja coerente buscar outros meios de cobrança mais céleres e menos custosos. Para o cálculo, foi considerado a movimentação dos processos de Execução Fiscal e a remuneração dos servidores. Encontrou-se duas classificações de processos predominantes, com custos distintos por processo. Para os processos de IPTU um custo de R$ 1.210,83 e para os processos de ISS R$ 1.204,76. Caso o município não executasse judicialmente os processos abaixo desse valor, ele poderia ter economizado R$ 14.458.940,33 entre 2016 e 2018. Com o estudo, foi elaborada e aprovada uma legislação para autorizar o não ajuizamento e a desistência de ações judiciais com valores inferior ao custo mínimo. O artigo contribui com a possibilidade de transferibilidade dos achados para outros municípios, otimizando a Execução Fiscal municipal.
REFLEXÕES SOBRE A UTILIZAÇÃO DO MODELO DISTRITAL MISTO DE SUPERPOSIÇÃO NO PLEITO PARA O PARLAMENTO MUNICIPAL
Authors: Júnior Clóvis , Da Silveira Sebastião Sergio
Published: January 2025

O presente artigo tem como objetivo demonstrar a possibilidade da adoção do sistema eleitoral distrital misto por superposição nas eleições para o Parlamento municipal como uma das soluções para a crise de representatividade experimentada em nosso país. Se a democracia é um trilho a ser percorrido, entendida como um processo, a cidadania é sua locomotiva. Sem ela, a democracia perde qualquer sentido. A participação popular nas decisões políticas precisa ser resgatada, especialmente quanto aos representantes do povo. Diante da ineficácia do sistema proporcional nesse sentido, que só tem colaborado para o aumento da distância entre os eleitores e os eleitos, apresenta-se a hipótese da mudança do sistema eleitoral como um experimento constitucional. Isso porque, na teoria, a proposta trazida parece superar suas principais críticas, de maneira que apenas a prática demonstrará eventuais imperfeições. Para elaboração da pesquisa, utilizou-se as bases bibliográfica e documental, de abordagem qualitativa, sendo os dados levantados e analisados pelo método científico hipotético-dedutivo.
O FILTRO INVISÍVEL
Authors: Maso Borba Navolar Ana Lúcia
Published: January 2025

Eli Pariser, ativista e autor, apresenta em “O Filtro Invisível” uma análise do impacto da personalização algorítmica na maneira como informações são consumidas na internet. Partindo de um contexto histórico e técnico, o autor explora como plataformas digitais utilizam algoritmos para criar universos informacionais exclusivos, moldando não apenas as experiências individuais, mas também dinâmicas sociais amplas. A obra é estruturada em torno da ideia central da "bolha dos filtros", conceito que descreve o isolamento informacional gerado pela hiperpersonalização de conteúdos.
Psicologia escolar e gênero: uma revisão sistemática
Authors: Linhares Santos Isabele , Alves de Moraes Aline , Negreiros Fauston , Borges Formiga Sobrinho Asdrúbal
Published: January 2025

O debate sobre gênero sofreu ataques expressivos por movimentos político-religiosos ultraconservadores nos últimos anos. A Psicologia, embora tenha contribuído historicamente com perspectivas e práticas normatizantes e disciplinares, é convocada a posicionar-se diante de tais questões. Esta investigação exploratório-descritiva realizou uma revisão sistemática, com base nos critérios do PRISMA, acerca da produção científica em psicologia escolar e gênero nos últimos 10 anos. Utilizou-se como fonte de dados as bases Scopus, PubMed, Scielo e Web of Science. As publicações foram selecionadas em inglês, português e/ou espanhol, indexadas entre janeiro/2012 e dezembro/2022. Encontrou-se 40 artigos e, somente, 08 atenderam aos critérios de elegibilidade. O estudo revelou que, embora gênero na Psicologia Escolar venha sendo pensado em uma perspectiva crítica e decolonial, existem lacunas no número de produções, modalidades de pesquisas e abordagem de diferentes níveis educacionais. Espera-se que esses dados possam evidenciar a necessidade de que os discursos se materializem em produções científicas.
Atuação do psicólogo (a) escolar e educacional: relato de experiência em iniciação científica
Authors: Lessa Patricia Vaz de , Armelin Rafael Guillardi
Published: January 2025

O contexto escolar é um ambiente social complexo, no qual as relações se estabelecem, e se faz profícuo para a formação dos estudantes em psicologia. O objetivo deste artigo é apresentar um relato de experiência de iniciação científica sobre a atuação do psicólogo escolar e educacional na perspectiva da Psicologia Histórico-Cultural em uma escola do estado do PR. As atividades foram desenvolvidas por duas estudantes em uma escola municipal, no norte do Paraná, em uma sala de 3º ano, realizada em grupos. Após o período de observação participante, foi realizado uma análise institucional e elaboração de um plano de ação que foi implementado na sala de aula. Como resultados, foi possível observar, estudantes engajados na realização das propostas, nas atividades de rotina escolar, propiciando melhor socialização, exercitando a expressão, as habilidades sociais e, o reconhecimento das próprias emoções nas diversas situações.
Bioconstrução como Alternativa Sustentável para a Ocupação do Espaço Urbano
Authors: Aristides Rodrigo Lourenço , Nabarro Sergio Aparecido
Published: January 2025

A partir de breves comentários sobre o déficit habitacional brasileiro, o grande passivo envolvendo resíduos de construção civil nas cidades, as políticas públicas de habitação ainda ineficientes, bem como a característica ainda despreocupada da arquitetura atual com a sustentabilidade, este artigo propõe pensar a bioconstrução como novo modelo de construção, baseado na utilização de materiais mais econômicos e sustentáveis, ao mesmo tempo em que resgata o saber fazer dos sujeitos (mutirão e autoconstrução) como alternativa para o acesso a moradia. Por meio da apresentação de um dos princípios da permacultura, da necessidade de adequação da ocupação humana no lugar e da insuficiente existência de normas técnicas brasileiras (NBR´s) que envolvam novos formatos de construção civil, percebe-se que a existência de construções não convencionais e/ou sustentáveis ainda é insuficiente já que demanda apoio governamental, carência possivelmente justificada pela falta de profissionais técnicos com aptidão para tal modalidade de construção. Por essas razões a ocupação dos cidadãos no espaço urbano deve ser pensada a partir da preocupação social e ambiental, bem como da viabilidade econômica, objetivos esses potencialmente alcançáveis por meio da bioconstrução, que se mostra como uma alternativa viável e sustentável para ocupação de espaços urbanos.
Semiárido Nordestino
Authors: Santana Helton Costa , Santos Simone Ribeiro
Published: January 2025

O presente artigo tem como objetivo socializar experiências de práticas de ensino vivenciadas durante as aulas de Geografia nas turmas do  7° ano do Ensino Fundamental II da Escola Municipal Dr. Luiz Navarro de Britto, que faz parte da rede pública de educação no Município de Saúde - BA, cuja temática envolve a região Nordeste do Brasil. A questão que mobiliza esta escrita é: Como o professor de Geografia do Ensino Fundamental II pode abordar temáticas vinculadas ao Nordeste brasileiro de modo a desconstruir estereótipos sobre esta região? Trata-se, portanto, de um relato de experiência, cuja prática de ensino esteve ancorada no estudo do semiárido nordestino, a partir de textos e imagens que retratam a referida temática que compõe o currículo da Geografia escolar, o que possibilitou perceber o ponto de vista dos discentes no que concerne ao seu imaginário sobre o sertão nordestino. Esta experiência permite afirmar que, por meio de uma educação contextualizada e crítica, o professor deve promover uma prática pedagógica que construa saberes não estereotipados que permitam formar estudantes capazes de compreender reflexivamente a   realidade em que se encontram, com consciência crítica em relação ao que ensina e ao que se aprende.
O Método Pressão-Estado-Impacto-Resposta (PEIR) Aplicado em Estudos Ambientais: uma revisão sistemática
Authors: Ribeiro Maria Teresa , Rodrigues Gelze Serrat de Souza Campos
Published: January 2025

A Organização para a Cooperação e Desenvolvimento Econômico (OCED) formulou, em 1993, os indicadores ambientais Pressão-Estado-Resposta (PER). Posteriormente, o Programa das Nações Unidas para o Meio Ambiente (PNUMA) adaptou esse método que passou a ser chamado PEIR. É um método de avaliação de impactos ambientais baseado no conceito de causalidade, pois propõe que a análise ambiental ocorra a partir do estudo dos fatores que exerçam PRESSÃO sobre determinado meio causando seu ESTADO atual, caracterizado por meio de indicadores. Com isso é possível avaliar IMPACTOS ambientais decorrentes de determinada situação. Para lidar com o estado ambiental a sociedade oferece RESPOSTAS, incluindo ações individuais e coletivas, visando mitigar, adaptar ou prevenir impactos negativos no ambiente. Este artigo apresenta uma revisão sistemática acerca desse método, realizada por meio de um levantamento de literatura utilizando a plataforma ‘Portal de Periódicos da Capes’. O objetivo foi levantar informações sobre a aplicabilidade desse método em estudos ambientais referentes a atividades econômicas e contextos diversos. Os resultados apontam para o caráter adaptável do método PEIR para diferentes locais e contextos geográficos, e sua utilidade é observada em processos de gestão ambiental e identificação de impactos ambientais e suas causas, a qual possibilita a compreensão do ambiente enquanto sistema de múltiplas interações.
Crônicas do barro e contornos do lugar periférico em Criolo e Sérgio Vaz
Authors: Fernandes João Paulo
Published: January 2025

É objetivo do artigo analisar o lugar periférico nas vozes de Criolo na canção “Não existe amor em SP” em diálogo com o livro que tangencia os versos “Literatura, pão e poesia: histórias de um povo lindo e inteligente”, de Sérgio Vaz, com ênfase na crônica “Mil graus na terra da garoa”. Posto o relevo na escrita de entremeio aos versos produzidos por Vaz, surge não menos poética a memória em crônicas, as quais fecundam um eu já conhecido da e na periferia paulista que reverbera, especialmente, os espaços da comunidade e da escola em oficinas de poesia e saraus; flertando com outro poeta urbano, que para além das palavras, comunga no ritmo e cadência do sobreviver em espaços marginalizados, o Criolo; e ambos norteiam a metodologia de análise crítica das produções litero-cancional as quais se volta nosso olhar. Tais diálogos são exemplos de hibridez artística que se dão pela linguagem, matéria de realização do pensamento, e podem ser compreendidos pelas contribuições teórico-críticas de Paulo Leminski (2011), quando reflete sobre o prazer da linguagem, enquanto que Charles A. Perrone (2008) contextualiza a canção brasileira em interface com a linguagem poética concebida por Octavio Paz (2012), refletindo as nuances sociológicas nas palavras de Heloisa Buarque de Holanda (2020) acerca dos limites da periferia. Ancorados nesses vieses, reconhecemos os autores, suas vozes e ecos do (r)existir na projeção dos lugares que foram ambientes de nascimento, identidade e luta de corpos invisibilizados, na ambivalência da linguagem que redimensiona o lugar em intercâmbio com o centro urbano e seus contornos, que tornam a poesia alimento sustentável aos sujeitos empobrecidos pela sociedade.
Effectiveness of Bupivacaine Infiltration in Reducing Postoperative Pain in Patients Undergoing Percutaneous Nephrolithotomy
Authors: Raza Ali , Khursheed Sana , Ahmed Waqas , Rajpar Zakir Hussain , Soomro Naveed , Kumar Raj , Shah Syed Zulfiquar Ali
Published: January 2025

Percutaneous Nephrolithotomy is a standard way to treat large renal calculi because it is slightly invasive. One big problem with normal percutaneous nephrolithotomy, though, is that patients often have discomfort and pain at the nephrostomy place after the surgery. Objective: To evaluate the effectiveness of bupivacaine infiltration in reducing postoperative pain in patients undergoing percutaneous nephrolithotomy. Methods: The quasi-study lasted for six months at Liaquat National Hospital in Karachi. A total of 60 patients were recruited as Group A=30 patients (20ml/50mg of 0.25% bupivacaine) and Group B=30 patients (20ml of normal saline). All the patients had percutaneous nephrolithotomy and at the end of the operation; a 12 Fr nephrostomy tube was put in place. All patients were carefully watched, and their pain levels were measured using a visual analogue scale and computed as mean ± SD. Results: Group A had a mean age of 39.9 ± 12.9 years, and Group B had a mean age of 39.4 ± 11.2 years. There were 16 men (53.3%) and 14 women (46.7%) in Group A, and 20 men (66.7%) and 10 women (33.3%) in Group B. The average amount of pain after surgery was 2.07 ± 0.78 in Group A and 4.80 ± 0.92 in Group B. The p-value was found to be extremely significant, which means it was 0.0001. Conclusion: It was concluded that the postoperative pain score was significantly better in bupivacaine infiltration as compared to placebo in percutaneous nephrolithotomy.
Cellular and Molecular Mechanisms of Salivary Gland Development and Regeneration: Implications for Tissue Engineering and Regenerative Medicine
Authors: Ahmed Zain-Ud-Din , Rao Maheen , Jawad Fatima , Khan Safi Ullah , Rehman Taha , Rahim Majida
Published: January 2025

Salivary glands are essential for oral health, but their function can be compromised by cancer, autoimmune disorders, infections, and physical traumas, severely impacting quality of life. There is currently no cure for salivary gland dysfunction, and treatment is symptomatic. Objective: To explore the cellular and molecular mechanisms involved in the development, maturation, and regeneration of salivary glands, with a focus on tissue engineering and regenerative medicine. Methods: A comprehensive review was conducted using PRISMA and information was fetched through PUBMED, EMBASE, Medline, and Google Scholar databases. Results: The FGF pathway, part of the growth factor family, plays a significant role in salivary gland homeostasis, while the Wnt pathway is crucial for gland maturation. Various receptors and signaling molecules are involved in the gland's functioning. Recent advancements in regenerative medicine have demonstrated that activating endogenous stem cells can lead to positive outcomes in restoring injured salivary glands. Technological advancements in 3D tissue culturing using patient cells have enabled the creation of functional artificial salivary gland organs. However, no cell line completely mimics natural salivary gland cells, and their inherent tumorigenic potential delays their therapeutic application. Conclusions: Understanding these mechanisms is vital for developing effective therapies. While recent advancements show promise, further research is necessary to create safe, accurate cell lines for therapeutic use. This knowledge is crucial for establishing therapeutic avenues that could potentially lead to direct regeneration, reconstruction, and replacement of functioning salivary glands.
A Comparative Study of Perioperative Blood Loss in Monopolar Versus Bipolar Transurethral Resection of the Prostate: Quasi Experimental Study
Authors: Ali Rao Nouman , Irfan Muhammad , Mahmood Athar , Ahmad Muhammad Zahid , Irfan Sohaib , Shahzad Shafqat
Published: January 2025

Transurethral Resection of the Prostate (TURP) is frequently performed for Benign Prostatic Hyperplasia (BPH), and the choice between monopolar and bipolar diathermy influences blood loss. Minimizing blood loss is crucial for reducing complications and improving recovery, with bipolar diathermy generally offering better hemostasis than monopolar diathermy. Objective: To compare perioperative blood loss in monopolar versus bipolar transurethral resection for benign prostatic hyperplasia. Methods: Quasi experimental study was conducted at the Department of Urology and Renal Transplantation, DHQ Hospital Gujranwala, from December 11, 2018, to June 11, 2019. Patients were assigned to either Group A, which received monopolar diathermy, or Group B, which received bipolar diathermy, using convenience sampling technique. Each group comprised 40 patients. Hematocrit levels were assessed 24 hours’ post-surgery; hematocrit, the proportion of blood volume occupied by red blood cells, serves as an indirect measure of blood loss. Blood loss during surgery was estimated by comparing pre-operative and post-operative hematocrit readings, and the data were analyzed using SPSS version 23. Results: Perioperative blood loss was significantly higher in patients who underwent monopolar diathermy compared to those treated with bipolar diathermy (monopolar: 325.22 ml vs. bipolar: 240.0 ml, p-value = 0.0001). Similar findings were observed when stratifying by age and prostate size, indicating that bipolar TURP consistently resulted in less perioperative blood loss. Conclusions: A significant reduction in perioperative blood loss with bipolar TURP compared to monopolar TURP in BPH patients. Reduction is clinically relevant, as it may lead to lower morbidity and improved recovery times.
Gender based Correlation between Hand measurement and Height in Medical Students of Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Sindh
Authors: Ram Hari , Talpur Mir Ghulam Ali , Abro Farooq Ahmed , Qayyum Sadia Abdul , Kazi Salman Ahmed Farsi , Qadri Naveed Ali
Published: January 2025

Anthropometry was an organized measurement procedure used in physical anthropology. Hand dimensions can represent an individual’s identity. Stature, a complex of linear dimensions, correlates with various body parts. Objective: To explore the gender-wise correlation between hand measurement and stature across a diverse population for estimating the stature of MBBS Medical Students of Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Sindh. Methods: It was descriptive cross- sectional study and its sample size was calculated by using Open-epi online calculator. Non convenience sampling method adopted while collecting the data. Research invitations were extended to MBBS students of SMBBMU to participate in a research project and only 354 voluntarily agreed to participate out of which 169 (47.7%) males and 185 (52.3%) females fulfilled the inclusion criteria and written informed consent were taken before proceeding of data collection. Results: For both males and females, hand breadth measurements were strongly correlated with each other. The height of hands was also strongly correlated between left and right hands, particularly in males. Those who were involving age or overall height, were generally weaker and not always statistically significant. Males show more significant and stronger correlations between hand measurements and other variables compared to females, who have some significant but generally weaker correlations. Conclusion: The findings underscore that taller individuals generally possess larger hand dimensions, and marked differences exist in hand measurements between males and females