bluuebunny/crossref_metadata_2025 huggingface dataset:
MELINDUNGI ANAK DARI KONTEN NEGATIF INTERNET: STUDI TERHADAP PERAMBAN WEB KHUSUS ANAK
Authors: Ulinnuha Masyari
Published: September 2017

Dunia teknologi dan internet berkembang sangat pesat di dunia, tak terkecuali Indonesia. Imbasnya, jumlah pengguna internet saat ini semakin besar dan bertambah terus setiap harinya. Sebagian dari pengguna internet tersebut adalah anak-anak. Sementara banyak sekali situs web yang tidak layak men­jadi konsum­si anak-anak. Untuk itu diperlukan pembatasan bagi anak-anak dalam mengakses situs web.Tulisan ini mem­bahas be­berapa peramban web khusus anak. Ada 4 peramban yang dibahas yaitu KidZui, Hoopah Kidview Computer Explorer, Peanut Butter PC dan NoodleNet. Keempat peramban tersebut dengan segala ke­lebihan­nya bisa menjadi alternatif untuk mem­batasi anak dari dunia internet yang sangat luas. Namun keempat peram­ban tersebut tetap mempunyai kelemahan se­hingga peran orang tua tetap di­perlu­kan agar anak tidak ter­jebak ke dalam situs yang tidak layak.
Stage IB Endometrioid Type Endometrial Cancer: The Role of Lymphadenectomy and Adjuvant Radiation Therapy
Authors: Turkmen Osman , Tasci Tolga , Basaran Derman , Comert Kimyon Gunsu , Karalök Alper , Ureyen Isin , Turan Taner
Published: September 2017

Objective: Both performances of lymphadenectomy and benefit of adding adjuvant radiotherapy are controversial for patients with International Federation of Gynecology and Obstetrics stage IB endometrioid type endometrial cancer. We aimed to identify the role of lymphadenectomy and adjuvant radiation therapy as well as clinicopathological prognostic factors for this group of patients.Study Design: Records of all patients (n=132) with stage IB endometrioid endometrial cancer who were referred to or treated in our institution between Jan 1992 and Dec 2013 were retrospectively reviewed. Cox Proportional Hazard Regression Analysis was used to determine the effects of lymphadenectomy and adjuvant radiation as well as other clinicopathological factors on disease free survival and overall survival.Results: Mean age was 59.9 years (range, 45-82). Lymphadenectomy didn't perform in 36 (27.3%) patients and 23 (17.4%) patients did not have any kind of adjuvant treatment. Mean lymph node count was 18.8 (range, 3-67). Federation of Gynecology and Obstetrics grade, lymphovascular space invasion, lymphadenectomy, receiving adjuvant treatment and type of received adjuvant therapy were not associated with disease free survival and overall survival for the entire cohort. In a subgroup of patients with grade1&2 tumor, 5-year disease free survival rates were 80% and 50% (p=0.4), respectively and overall survival rates were 94.8% and 93.8% (p=0.2), respectively for patients who had or didn't have adjuvant radiotherapy. While performance of lymphadenectomy was not significantly associated with disease free survival in this subgroup (p=0.56), this association was statistically significant for overall survival (97.9% vs. 86.4%, p=0.04) Conclusion: Benefit of adjuvant radiotherapy in regard to prevention of recurrence needs to be confirmed by further studies. Lymphadenectomy had a survival benefit for patients with myometrial invasion greater than a half of myometrial thickness.
Prosthodontic Rehabilitation of Arabic Speaking Individuals with Velopharyngeal Incompetence: A Preliminary Study
Authors: Bibars Abdel Rahim M. , Alfwaress Firas S.D. , Hamasha Abed Al-Hadi , Al-Hourani Zeid A. , Almhdawi Khader
Published: September 2017

Background:

Hypernasality is a frequently encountered problem in the speech of individuals with velopharyngeal incompetence. The use of palatal lift appliance (PLA) is the main treatment option for correction of velopharyngeal incompetence. The literature on the outcomes of using prosthetics treatment for Arabic speaking patients is scarce.

Objective:

The aim of this study was to investigate the effect of using PLA on hypernasality of Arabic speaking patients with velopharyngeal incompetence.

Methods:

Six participants with age ranging from 9 to 61 years (4 males and 2 females) were recruited between October 2013 and August 2014. Written informed consents were taken from all the adult participants/the guardians of under-aged participants. All patients exhibited hypernasality with different etiologies for velopharyngeal incompetence (head injury, cerebrovascular accident, and neurological disorders). They were treated with PLAs which were constructed to elevate the dysfunctional soft palate. Nasalance scores and perceptual speech acceptability ratings were measured/evaluated in both situations; with and without appliances. Paired t-test was used to analyze the perceptual ratings and nasalance scores in order to detect any significant change in hypernasality pre and post insertion of PLA.

Results:

There was a statistically significant decrease (p>0.05) in nasalance scores (Pa, Pi, Ma, Mi, a, i) after PLA insertion. The subtest /u/ showed insignificant change (p= 0.056). Perceptual ratings showed significant reduction in hypernasality which was consistent with nasalance measurements.

Conclusion:

PLAs can reduce hypernasality in Arabic speaking patients who suffer from velopharyngeal impairment.
Sexually Transmitted Infections in the PReP Era. Are Family Doctors Ready to Give Advice?
Authors: Rodríguez Cerdeira Carmen , Blanco E Sánchez , Blanco B Sánchez , Gregorio M Carnero
Published: September 2017

Background:

Pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) as a method of HIV prevention is not without controversy, and there has been concern that it may lead its users to think that they no longer need other preventive measures such as condoms. Thus, healthcare providers are convinced that PrEP decreases condom use and increases sexually transmitted infections (STIs). This treatment has been studied in men who have sex with men, men and women in heterosexual HIV-discordant couples, and heterosexual men and women.

Objective:

The objective of this study was to review the current state of evidence on the association of PrEP with condom use, the incidence of STIs, and the change in sexual behaviours in populations with risky practices.

Materials and Methods:

PubMed (National Center for Biotechnology Information, Bethesda, MD, USA), Science Direct (Elsevier Ltd., Oxford, UK), and Google Scholar (Google Inc., Mountain View, CA, USA) search engines were used during the study. We used the terms HIV, PrEP, sexually transmitted infections (STIs), MSM, condom, heterosexual men / women to search the databases.

Results:

Here, we present evidence that daily oral treatment is safe and effective in these populations studied, especially when medication adherence is high. STI testing should include extra-genital testing regardless of PrEP use to prevent health deficits and onward transmission.

Conclusion:

Despite this safety and efficacy, we strongly advise that patients continue to use condoms as a prophylactic measure against other sexually transmitted diseases. This update addresses the benefits and precautions that must be taken when establishing PrEP treatment, focusing mainly on family doctorswho are best positioned to provide follow-up and advice to patients and their relatives.
Analisa Postur Kerja Menggunakan Metode OWAS dan RULA
Authors: Bintang Alfin Nur , Dewi Shanty Kusuma
Published: September 2017

Material handling activities of sugar in PG Tjoekir storage warehouse is done manually. Continuous material handling activity can cause musculoskeletal disorders to workers. The distribution of questionnaires Nordic Body Map known some complaints experienced by workers in the process of material handling sugar. The OWAS and RULA methods are methods for evaluating and analyzing worker attitudes that can cause musculoskeletal disorders. Some activities in the storage warehouse PG Tjoekir is ranging from lifting, moving and putting sugar. OWAS method calculation results obtained risk level score 3. Risk level risk of RULA method 4. The calculation results show some worker posture causing musculoskeletal risk so that need improvement. Proposed repair work posture is to design two-wheeled hand truck. Hand trucks help reduce the risk of musculoskeletal injuries for workers.
La conciencia fonológica en el aprendizaje de la lectura convencional en un grupo de niños de 5 a 8 años
Authors: Muñoz Sánchez Yessica , Melenge Escudero James Alexander
Published: September 2017

Objetivo: evaluar el nivel de conciencia fonológica de los niños y niñas del grado primero de la Institución Educativa Rural José Antonio Galán, sedes Bajo Corinto y Maracas, como prerrequisito para el aprendizaje de la lectura convencional. Metodología: investigación de enfoque cuantitativo con diseño descriptivo, mediante la aplicación de la prueba EGRA (Early Grade Reading Assessment), que permite valorar el dominio de competencias indispensables para el aprendizaje de la lectura convencional. Hallazgos: ha sido posible determinar cómo los bajos niveles de desarrollo de la conciencia fonológica se relacionan con el nivel de adquisición del proceso de lectura convencional alcanzado por cada sujeto. Conclusiones: el nivel de desarrollo de la conciencia fonológica en la mayoría de la población evaluada, es silábico. Es necesario dar continuidad desde el área de psicología a la indagación en este contexto por las situaciones emergentes sobre la población y las problemáticas identificadas desde sus dinámicas relacionales.
Technologia building information modeling w pracy inspektora nadzoru inwestorskiego
Authors: Zima Krzysztof
Published: September 2017

The aim of the article is to present the possibilities of using BIM in the work of supervision inspector. In the article were analyzed the activities that must performed supervision inspector. Activities are summarized based on studies of contractual clauses in the tender procedures for the investor’s supervision service. Identified activities are divided into those that do not require a support of BIM technology and those in which this assistance is possible to use and can bring quantifiable benefits. Then were presented possibilities and potential benefits of supporting selected activities with use of BIM technology.
Drafting the Substance Materials of The Regional Regulation of Badung Regency on Public Service
Authors: Astariyani Ni Luh Gede , Nurmawati Made
Published: September 2017

The Government of Badung Regency provides public services, both in the forms of services and goods, to its community as part of its duty in performing governance. In the implementation, such public services are regulated in regulation which is derived from the existence of policy in the delegation of authority. The regional regulation as such is containing what so called the substance materials. The substance materials of Regency/City Regional Regulation mean that such regulation contains typical substance materials that are not contained in other Laws and Regulation both in the local and central level. The formulations of legal norms in the Regional Regulation are conducted by using the single and pairs formulations. The targets that will be realized, the scope of regulation and drafting direction of Regional of Badung Regency on Public Services, among others: scope of public services, integrated service system, guidelines for the standrad services preparation, the proportion of community groups and categories in a tiered services and community participation in performing the service.
A Anotação ao Acórdão do STJ de 13 de Setembro de 2007 o Problema da Qualificação e Regime dos Contratos de Instalação de Lojista em Centro Comercial
Authors: Afonso Ana
Published: September 2017

O caso submetido ao julgamento do Supremo Tribunal de Justiça recoloca o problema da qualificação e definição do regime jurídico dos contratos de exploração de loja em centro comercial. Apesar de não se tratar de um problema recente, e que foi já amplamente debatido pela doutrina e pela jurisprudência, justifica-se mais uma vez a respectiva análise. Assim, propomo-nos abordar aqui as questões conexionadas com o tema, que foram concretamente objecto de litígio perante o Supremo Tribunal.
Revisitando a Problemática do Efeito Directo do Acordo Sobre Contratos Públicos (OMC)
Authors: Santos José Alvaro Poças
Published: September 2017

A problemática genérica do efeito directo das normas de acordos internacionais concluídos pela Comunidade Europeia tem sido amplamente estudada e constitui um dos temas clássicos acerca das relações entre o Direito Internacional, a Ordem Jurídica Comunitária e os ordenamentos internos de cada um dos Estados-Membros. Não se pretende com o presente relatório tratar, ainda que perfunctoriamente, esse vasto campo de estudo, o que seria de todo descabido e desproporcionado face ao escopo e à natureza do estudo que ora se introduz.
Learning Chemistry by ICT (Virtual Animation) at Maumere High School, East Nusa Tenggara
Authors: Yusuf Yusnidar
Published: September 2017

This research was aimed to create attractive learning atmosphere which can make students excited inside theclass.Education was a right for every nation. It had to be given to improving a nation. Chemistry subject, especially in hydrocarbon chapter, was less-favorable by most students due to its difficulty level. Learning outcomes score were low. Many research showed that various method, strategy or another approach in teaching chemistry subject had significantlyimproved towards learning theoutcome of students.  One of the approaches was by virtual animation as part of ICT. Based on data result analysis from this research, there was 0,000 < α = 0.05 significance. As result, H0 was rejected. Itmeans that there was significant improve learning outcome using multimedia animation. The role of ICT as learning model should be utilised for granted by teachers to enriched chemistry science in school’s scope.
The Implementation of Icloud System Based on Knowledge Sharing at The University of Maarif Hasyim Latih Sidoarjo
Authors: Rodli Achmad Fathoni
Published: September 2017

This article presents the results of the analysis on the development of knowledge sharing processes and absorbs knowledge sharing activity, it is to increase the ability of the head of Departement at the University of Maarif Hasyim Latif and in innovating and in managing the Departement. The role of Information Technology in accommodating the knowledge sharing process is the development of the activities of managing and absorbing science courses to improve performance and provide added value and a competitive advantage in improving the quality performance of the head of Departement.  Design research is to find out how the problems that arise in the process of knowledge sharing and absorbing. Data collected by the identification of issues related to knowledge management based on Information Technology at the University of Maarif Hasyim Latif through observation, interviews, and documentation. Results of this study were to prove that iCloud system model developed at the University of Maarif has been contributing to 1) the implementation of the knowledge sharing process of the development activity of sharing and absorbing knowledge at the University Maarif Hasyim Latif to improve the innovation of ability. 2) Information technology has a major role in supporting the process of knowledge sharing on the development and absorbs knowledge sharing activities.
Comparing Tolerance of Ambiguity in Veterinary and Medical Students
Authors: Hancock Jason , Hammond Jennifer A. , Roberts Martin , Mattick Karen
Published: September 2017

Current guidelines suggest that educators in both medical and veterinary professions should do more to ensure that students can tolerate ambiguity. Designing curricula to achieve this requires the ability to measure and understand differences in ambiguity tolerance among and within professional groups. Although scales have been developed to measure tolerance of ambiguity in both medical and veterinary professions, no comparative studies have been reported. We compared the tolerance of ambiguity of medical and veterinary students, hypothesizing that veterinary students would have higher tolerance of ambiguity, given the greater patient diversity and less well-established evidence base underpinning practice. We conducted a secondary analysis of questionnaire data from first- to fourth-year medical and veterinary students. Tolerance of ambiguity scores were calculated and compared using the TAMSAD scale (29 items validated for the medical student population), the TAVS scale (27 items validated for the veterinary student population), and a scale comprising the 22 items common to both scales. Using the TAMSAD and TAVS scales, medical students had a significantly higher mean tolerance of ambiguity score than veterinary students (56.1 vs. 54.1, p<.001 and 60.4 vs. 58.5, p=.002, respectively) but no difference was seen when only the 22 shared items were compared (56.1 vs. 57.2, p=.513). The results do not support our hypothesis and highlight that different findings can result when different tools are used. Medical students may have slightly higher tolerance of ambiguity than veterinary students, although this depends on the scale used.
Assembly FG: An Education Case Study Using QuickBooks as the AIS for a Small Manufacturing Business
Authors: Lambert S. Lane , Bee Sara
Published: September 2017

This education case is the first to use QuickBooks Premier Accountant to teach students foundation functionalities common to all Enterprise Resource Planning (ERP) systems that support discrete manufacturing. Students learn how to configure QuickBooks so that direct materials, direct labor and applied manufacturing overhead costs charged to work-in-process parts manufactured at lower levels of the BOM are rolled up into the costs of higher-level work-in-process parts and, ultimately, into the costs of the finished goods parts. Students set up raw materials, work-in-process and finished goods part numbers so that quantities and costs of parts on-hand are tracked in inventory on the Perpetual Inventory System to provide an inventory subsidiary ledger that continuously matches the manufacturing inventory account balances in the Chart of Accounts. Students learn the importance of configuring Off the Shelf (OTS) manufacturing systems in accurately costing manufactured discrete products, including setting up manufacturing accounts, employees, part numbers, and the BOM. As such, the case is designed to be used in Accounting Information Systems (AIS) courses that are already using QuickBooks to help students' better understand the general concepts covered in AIS textbooks on the Production Cycle that are not addressed in extant textbooks on QuickBooks.
One Ticket to the Matinee Please: A Case Designed to Teach Students Accounting Software (Peachtree) Skills
Authors: Hayes David C. , Cook Megan , LaRosa David
Published: September 2017

The purpose of this article is to provide a practical case (in a movie theatre setting) where students can become familiar with the functionality and utility of Peachtree Accounting Software. Students will learn how to set up a new company and track a month of financial information. Additionally, the project identifies potential weaknesses in the software's design and demonstrates how to set some user security levels to help mitigate the chances for misuse or theft. What makes this case unique is that it was designed by students for the purpose of instructing their peers on the features, as well as deficiencies or limitations, of the software package.
Integrating IT Frameworks into the AIS Course
Authors: Qian Jing , Ward Kerry , Blaskovich Jennifer
Published: September 2017

The contemporary business and regulatory environment dictate that accountants develop greater expertise in information technology, particularly in its risk and control aspects. Several approaches exist to assist with these aspects of information technology, with the primary ones being COSO ERM, COBIT, ITIL, and the ISMS family of standards, each developed by different groups with different objectives. While accounting students likely receive training in COSO ERM and COBIT, exposure to ITIL and the ISMS family is less common. This paper is motivated from the view that all four approaches are vital to the accountant's professional toolbox and should be incorporated into the AIS course. In this paper, we provide AIS instructors with a concise overview of the four approaches and offer an integrated framework that can guide teaching plans. We discuss how the approaches should not be viewed as separate and redundant bureaucratic models, but as complementary approaches that help an organization manage risks and controls.
Modeling the Budgeting Process: Enriching the Learning Environment Using Monte Carlo Simulations
Authors: Mensching Jim , Adams Steven J. , Gardiner Lorraine , Jones Nancy
Published: September 2017

This paper discusses the development and use of a budgeting case study and an object-oriented modeling tool to introduce the concept of uncertainty and risk in financial analysis to students in upper-division accounting information systems classes. The emphasis is on teaching the concepts involving probabilistic budgeted financial statements using an object-oriented, discrete event, Monte Carlo simulation model of a simplified business environment. Teaching materials have been developed and tested in an advanced AIS course typically taught to senior or graduate-level students. Assignments are designed to assist students in understanding probabilistic models of business planning, and specifically, in development of budgeted financial statements, to create a stronger understanding of the interrelation of business processes and to expose students to business modeling via simulations.
Implementing Generalized Audit Software in the Classroom
Authors: Matherly Michele , Watson Marcia Weidenmier , Ivancevich Susan
Published: September 2017

This paper describes resources designed to help instructors easily integrate the leading generalized audit software (GAS) packages, Audit Command Language (ACL) and Interactive Data Extraction and Analysis (IDEA), into their classes. Specifically, we provide project assignments, exam questions, as well as teaching notes describing implementation issues. The projects require students to: (1) evaluate sales and accounts receivable data, and then create confirmation letters by exporting data from GAS and then importing it into word processing software for a mail merge, (2) use inventory, accounts payable, and payroll data to work with expressions, filters, data extractions, and relations between tables, and (3) import a database and prepare several reports. We also present student self-assessment data on their ability to use GAS as well as their understanding of the general benefits and applications of GAS. The evidence suggests that hands-on projects can improve perceived knowledge of GAS regardless of student background, course format (group versus individual projects), or teaching method (self-study versus lab-time).
Registration of ‘NS Presser CLP’ Hard Red Spring Wheat
Authors: Heo H.-Y. , Blake N. K. , Lanning S. P. , Lamb P. F. , Nash D. , Wichman D. M. , Kephart K. D. , Stougaard R. N. , Miller J. H. , Reddy G. V. P. , Eckhoff J. L. , Chen C. , Menalled F. , Davis E. , Talbert L. E.
Published: September 2017

‘NS Presser CLP’ (Reg. No. CV‐1132, PI 679964) hard red spring wheat (Triticum aestivum L.) was developed by the Montana Agricultural Experiment Station and released in 2016 to the commercial partner Northern Seed LLC. NS Presser CLP is a two‐gene Clearfield wheat intended for use with the selective imidazolinone herbicide imazamox (Beyond, BASF Corp.). NS Presser CLP was developed by a single backcross of alleles for resistance to the imidazolinone herbicide class into the recurrent parent ‘Vida’. Vida has been the most widely grown hard red spring wheat cultivar in Montana since 2010. Alleles for herbicide resistance at TaAHAS1D and TaAHAS1B were selected during the backcrossing process and line derivation using polymerase chain reaction markers developed by BASF. Three years of replicated yield trials at a total of 23 sites showed that NS Presser CLP has yield potential under dryland production similar to Vida. NS Presser CLP showed tolerance to a 2× rate of imidazolinone herbicide (87.6 g a.i. ha−1) applied at three testing sites in each of 2 yr. It provides a high‐yielding Clearfield cultivar for dryland production in Montana and surrounding areas.
Registration of ‘Lariat’ Peanut
Authors: Chamberlin K. D. , Bennett R. S. , Damicone J. P.
Published: September 2017

‘Lariat’ (Reg. No. CV‐134, PI 676980) is a high‐oleic runner‐type peanut (Arachis hypogaea L. subsp. hypogaea var. hypogaea) that has enhanced Sclerotinia blight (caused by Sclerotinia minor Jagger) resistance when compared to the cultivar Red River Runner. Lariat was released cooperatively by the USDA‐ARS and the Oklahoma Agricultural Experiment Station in 2016. Lariat (experimental designation ARSOK‐R35) is the result of a cross between cultivar Red River Runner × PI 274193 in the USDA germplasm collection. In advanced line disease trials conducted over 5 yr, Lariat averaged only 12% incidence of Sclerotinia blight, whereas Red River Runner averaged 20% and the susceptible runner‐type check cultivar Flavor Runner 458 averaged 47%. Furthermore, Lariat does not exhibit a yield boost or significant reduction in disease incidence on fungicide application, as does Red River Runner. Thus, Lariat is greatly enhanced in resistance to Sclerotinia blight compared with Red River Runner and will not require fungicide application to increase yields. Results from Oklahoma state variety trials demonstrated that Lariat is indistinguishable from Red River Runner with regards to yield and grade, thus maintaining those highly desirable traits. Production of Lariat in fields where Sclerotinia blight is present will increase profits for the grower by $200 to $500 ha−1.
Improvement of Early Strength of Cement Mortar Containing Granulated Blast Furnace Slag Using Industrial Byproducts
Authors: Kim Jin-Hyoung , Lee Han-Seung
Published: September 2017

In the field of construction, securing the early strength of concrete (on the first and third days of aging) has been an important problem in deciding the mold release time (i.e., shortening the construction time period). Therefore, the problem of reduced compressive strength in the early aging stage caused by mixing granulated blast furnace slag (GBFS) with concrete must certainly be resolved. In this study, we conduct experiments to explore methods for generating a concrete that develops an early strength equivalent to that of 100% OPC. The objective of this study is the development of an early-strength accelerator (ESA) made from an industrial by-product, for a GBFS-mixed cement mortar. This study also analyzes the mechanism of the early-strength generation in the concrete to evaluate the influence of the burning temperature of ESA on the optimal compressive strength of the concrete. According to the results of the experiment, GBFS, whose ESA is burnt at 800 °C, shows an activation factor of 102.6–104.7% in comparison with 100% OPC on the first and third days during early aging, thereby meeting the target compressive strength. The results of the micro-analytic experiment are as follows: ESA showed a pH of strongly alkaline. In addition, it was found that the content of SO3 was high in the chemical components, thus activating the hydration reaction of GBFS in the early age. This initial hydration reaction was thought to be due to the increase in the filling effect of the hydrate and the generation of C-S-H of the early age by the mass production of Ettringite.
Typhonium giganteum Lectin Exerts A Pro-Inflammatory Effect on RAW 264.7 via ROS and The NF-κB Signaling Pathway
Authors: Wang Wei , Wu Hao , Yu Hongli , Zhang Xingde , Cui Guojing , Wang Kuilong , Mao Shanhu , Pan Yaozong
Published: September 2017

Typhonii rhizoma, a widely used herb in traditional Chinese medicine, has acute irritating toxicity related to Typhonium giganteum lectin (TGL). TGL exhibits acute inflammatory effects, but the underlying molecular mechanisms are largely unknown. This paper is designed to assess the pro-inflammatory response of TGL on RAW 264.7 cells. RAW 264.7 treated with 6.25, 12.5, 25, and 50 µg/mL TGL showed elevated levels of inflammatory factors (TNF-α, IL-1β) and of p-IκB and p-p65, all dose-dependent, indicating that TGL had a substantial inflammatory effect and mobilized the nuclear factor-κB (NF-κB) pathway. All four TGL treatments also induced the up-regulation of reactive oxygen species (ROS) and cytosolic free Ca2+ and down-regulation of mitochondrial membrane potential (MMP). The production of cytokines and p-IκB, p-p65 were reduced by N-acetylcysteine (NAC), an ROS scavenger, which somewhat abrogated ROS production. The results showed the TGL-activated inflammatory signaling pathway NF-κB to be associated with the overproduction of ROS. Moreover, 50 μg/mL treatment with TGL led to cell apoptosis after 1 h and increased necrosis over time. These results provided potential molecular mechanisms for the observed inflammatory response to TGL including up-regulation of ROS and cytosolic free Ca2+, down-regulation of MMP, the mobilization of the NF-κB pathway, and the subsequent overproduction of pro-inflammatory factors resulting in apoptosis. Long-term stimulation with TGL resulted in strong toxic effects related to inflammation that induced necrosis in macrophages.
Properties of Neutrino-driven Ejecta from the Remnant of a Binary Neutron Star Merger: Pure Radiation Hydrodynamics Case
Authors: Fujibayashi Sho , Sekiguchi Yuichiro , Kiuchi Kenta , Shibata Masaru
Published: September 2017

We performed general relativistic, long-term, axisymmetric neutrino radiation hydrodynamics simulations for the remnant formed after a binary neutron star merger, which consists of a massive neutron star and a torus surrounding it. As an initial condition, we employ the result derived in a three-dimensional, numerical relativity simulation for the binary neutron star merger. We investigate the properties of neutrino-driven ejecta. Due to the pair-annihilation heating, the dynamics of the neutrino-driven ejecta are significantly modified. The kinetic energy of the ejecta is about two times larger than that in the absence of pair-annihilation heating. This suggests that the pair-annihilation heating plays an important role in the evolution of merger remnants. The relativistic outflow, which is required for driving gamma-ray bursts, is not observed because the specific heating rate around the rotational axis is not sufficiently high, due to the baryon loading caused by the neutrino-driven ejecta from the massive neutron star. We discuss the condition for launching the relativistic outflow and the nucleosynthesis in the ejecta.
CANDELS: Elevated Black Hole Growth in the Progenitors of Compact Quiescent Galaxies at z ∼ 2
Authors: Kocevski Dale D. , Barro Guillermo , Faber S. M. , Dekel Avishai , Somerville Rachel S. , Young Joshua A. , Williams Christina C. , McIntosh Daniel H. , Georgakakis Antonis , Hasinger Guenther , Nandra Kirpal , Civano Francesca , Alexander David M. , Almaini Omar , Conselice Christopher J. , Donley Jennifer L. , Ferguson Harry C. , Giavalisco Mauro , Grogin Norman A. , Hathi Nimish , Hawkins Matthew , Koekemoer Anton M. , Koo David C. , McGrath Elizabeth J. , Mobasher Bahram , Pérez González Pablo G. , Pforr Janine , Primack Joel R. , Santini Paola , Stefanon Mauro , Trump Jonathan R. , van der Wel Arjen , Wuyts Stijn , Yan Haojing
Published: September 2017

We examine the fraction of massive (

) compact star-forming galaxies (cSFGs) that host an active galactic nucleus (AGN) at

. These cSFGs are likely the direct progenitors of the compact quiescent galaxies observed at this epoch, which are the first population of passive galaxies to appear in large numbers in the early Universe. We identify cSFGs that host an AGN using a combination of Hubble WFC3 imaging and Chandra X-ray observations in four fields: the Chandra Deep Fields, the Extended Groth Strip, and the UKIDSS Ultra Deep Survey field. We find that

(65/166) of cSFGs at

host an X-ray detected AGN. This fraction is 3.2 times higher than the incidence of AGN in extended star-forming galaxies with similar masses at these redshifts. This difference is significant at the

level. Our results are consistent with models in which cSFGs are formed through a dissipative contraction that triggers a compact starburst and concurrent growth of the central black hole. We also discuss our findings in the context of cosmological galaxy evolution simulations that require feedback energy to rapidly quench cSFGs. We show that the AGN fraction peaks precisely where energy injection is needed to reproduce the decline in the number density of cSFGs with redshift. Our results suggest that the first abundant population of massive quenched galaxies emerged directly following a phase of elevated supermassive black hole growth and further hints at a possible connection between AGN and the rapid quenching of star formation in these galaxies.
Giant Metrewave Radio Telescope Monitoring of the Black Hole X-Ray Binary, V404 Cygni during Its 2015 June Outburst
Authors: Chandra Poonam , Kanekar Nissim
Published: September 2017

We report results from a Giant Metrewave Radio Telescope (GMRT) monitoring campaign of the black hole X-ray binary V404 Cygni during its 2015 June outburst. The GMRT observations were carried out at observing frequencies of 1280, 610, 325, and 235 MHz, and extended from June 26.89 UT (a day after the strongest radio/X-ray outburst) to July 12.93 UT. We find the low-frequency radio emission of V404 Cygni to be extremely bright and fast-decaying in the outburst phase, with an inverted spectrum below 1.5 GHz and an intermediate X-ray state. The radio emission settles to a weak, quiescent state ≈11 days after the outburst, with a flat radio spectrum and a soft X-ray state. Combining the GMRT measurements with flux density estimates from the literature, we identify a spectral turnover in the radio spectrum at ≈1.5 GHz on ≈ June 26.9 UT, indicating the presence of a synchrotron self-absorbed emitting region. We use the measured flux density at the turnover frequency with the assumption of equipartition of energy between the particles and the magnetic field to infer the jet radius (≈4.0 × 1013 cm), magnetic field (≈0.5 G), minimum total energy (≈7 × 1039 erg), and transient jet power (≈8 × 1034 erg s−1). The relatively low value of the jet power, despite V404 Cygni’s high black hole spin parameter, suggests that the radio jet power does not correlate with the spin parameter.
Meterwavelength Single-pulse Polarimetric Emission Survey. III. The Phenomenon of Nulling in Pulsars
Authors: Basu Rahul , Mitra Dipanjan , Melikidze George I.
Published: September 2017

A detailed analysis of nulling was conducted for the pulsars studied in the Meterwavelength Single-pulse Polarimetric Emission Survey. We characterized nulling in 36 pulsars including 17 pulsars where the phenomenon was reported for the first time. The most dominant nulls lasted for a short duration, less than five periods. Longer duration nulls extending to hundreds of periods were also seen in some cases. A careful analysis showed the presence of periodicities in the transition from the null to the burst states in 11 pulsars. In our earlier work, fluctuation spectrum analysis showed multiple periodicities in 6 of these 11 pulsars. We demonstrate that the longer periodicity in each case was associated with nulling. The shorter periodicities usually originate from subpulse drifting. The nulling periodicities were more aligned with the periodic amplitude modulation, indicating a possible common origin for both. The most prevalent nulls last for a single period and can be potentially explained using random variations affecting the plasma processes in the pulsar magnetosphere. On the other hand, longer-duration nulls require changes in the pair-production processes, which need an external triggering mechanism for the changes. The presence of periodic nulling puts an added constraint on the triggering mechanism, which also needs to be periodic.
SÍGAME Simulations of the
,
, and
Line Emission from Star-forming Galaxies at
Authors: Olsen Karen , Greve Thomas R. , Narayanan Desika , Thompson Robert , Davé Romeel , Rios Luis Niebla , Stawinski Stephanie
Published: September 2017

Of the almost 40 star-forming galaxies at

(not counting quasi-stellar objects) observed in

to date, nearly half are either very faint in

or not detected at all, and fall well below expectations based on locally derived relations between star formation rate and

luminosity. This has raised questions as to how reliable

is as a tracer of star formation activity at these epochs and how factors such as metallicity might affect the

emission. Combining cosmological zoom simulations of galaxies with SÍGAME (SImulator of GAlaxy Millimeter/submillimeter Emission), we modeled the multiphased interstellar medium (ISM) and its emission in

, as well as in [O i] and [O iii], from 30 main-sequence galaxies at

with star formation rates ∼3–23

, stellar masses

, and metallicities

. The simulations are able to reproduce the aforementioned

faintness of some normal star-forming galaxy sources at

. In terms of [O i] and [O iii], very few observations are available at

, but our simulations match two of the three existing

detections of [O iii] and are furthermore roughly consistent with the [O i] and [O iii] luminosity relations with star formation rate observed for local starburst galaxies. We find that the

emission is dominated by the diffuse ionized gas phase and molecular clouds, which on average contribute ∼66% and ∼27%, respectively. The molecular gas, which constitutes only

of the total gas mass, is thus a more efficient emitter of

than the ionized gas, which makes up ∼85% of the total gas mass. A principal component analysis shows that the

luminosity correlates with the star formation activity of a galaxy as well as its average metallicity. The low metallicities of our simulations together with their low molecular gas mass fractions can account for their

faintness, and we suggest that these factors may also be responsible for the

-faint normal galaxies observed at these early epochs.
Damage caused by exposure to propofol during gestation of mice
Authors: Sensiate Lucimara Aparecida , Bispo Ana Clara Cerato , Guarido Karla Lorena , Freckleton Joelle Toni-Ann Venice , Salles Maria José
Published: September 2017

Literature shows that surgical procedure could be necessary at any stage of pregnancy and can cause adverse effects on the mother and fetus. One of the most used anesthetics in surgical centers is propofol however; the safety during pregnancy has not been completely established. The objective of this study was to investigate the possible toxic and teratogenic effects on the intrauterine and post-natal development of mice exposed to the dose of 15 mg kg-1 propofol on the caudal vein fifth, tenth and fifteenth day of gestation. A significant reduction in weight gain was observed in female mice who received a 15 mg kg-1 dose of propofol on the fifth gestational day. A higher rate of embryonic loss post implantation and resorption was also observed in this group. In regards to physical development, the anesthetic increased significantly the offspring weight gain, the time in which pinna detachment occurred, and the anogenital distance of pups whose females received propofol on the fifteenth day of gestation. Based on these results, we concluded that administration of propofol in the beginning stages of gestation increases the number of abortions and promotes alterations in the physical development of pups whose mothers were anesthetized in the final stages of gestation.
Factores asociados a la respuesta de Pocillopora spp. (Anthozoa: Scleractinia) durante un proceso de restauración en la costa del Pacífico mexicano
Authors: Muñiz Anguiano Daniela , Verduzco Zapata Manuel , Liñán Cabello Marco A.
Published: September 2017

Durante un proceso de restauración de Pocillopora spp., usando corales de oportunidad (CO), fueron evaluados diversos atributos bióticos en dos sitios a lo largo de un año, de manera bimensual fueron determinadas las concentraciones de aminoácidos tipo micosporina (AAMs) y niveles de clorofila a (Cl a). De manera específica, en el último muestreo se realizó un análisis de malonaldehido (MDA) y se calcularon las relaciones ARN/ADN y proteína/ADN como indicadores de estrés oxidativo y actividad trascripcional en simbionte y cnidario de todos los morfotipos. En sitio Carrizales (SC) la técnica de restauración de ramilletes coralinos (RC) promovió la integración de COs registrando signos de recuperación y altas tasas de supervivencia (90%); no obstante, en el Sitio Juluapan (SJ), se observó una falta de respuesta a los indicadores bióticos y moleculares asociados a la recuperación. Por lo tanto, los CO provenientes de Carrizales no fueron capaces de aclimatarse a un sitio en el que imperan distintas condiciones ambientales. Altas concentraciones de Cl a, AAMs, y una alta relación ARN/ADN fueron características de una condición saludable de corales, que a su vez, estuvieron asociados a los indicadores de restauración y mejor supervivencia observada.
A reappraisal of investigations into strata permeability changes associated with longwall mining
Authors: Aston T R C , Singh R N
Published: September 2017

Longwall mining results in a redistribution of strata stresses, which affect the natural insitu permeability regime. After a brief review of current conceptual models used to explain this phenomena, a comprehensive examination is made of all results obtained from
investigations undertaken by Nottingham University to monitor insitu permeability changes under field conditions. To facilitate a unified approach, all the original results, where available, have been re-analysed using cumulative difference analysis. The results are discussed with respect to three
identifiable areas which occur around a longwall panel: ahead of the face line, the face end and the ribside pillar.
Preventive geotechnical engineering and its application to the Lingan-Phalen and Donkin-Morien development projects: a discussion paper
Authors: Cain P
Published: September 2017

The need for the application of the concepts of preventive geotechnical engineering to major mine developments is emphasized. An approach suitable for adoption at the Donkin-Morien and Lingan-Phalen development projects is described, based on the development of a
trial retreat system.
The computer modelling of surface coal mining operations
Authors: Srajer V
Published: September 2017

In 1982 the CANMET/Calgary Coal Research Laboratory and the National Research Council in Ottawa established a joint federal/industrial research group to develop and test various computer models for application in surface coal mining operations in western Canada.
This paper summarizes the experience if the group, with respect to: - Defining model specifications and industrial requirements. - Developing a general mine model for the TransAlta Utilities Highvale Mine in Alberta. Potential model appliations for other mining companies are discussed. An overall
structure for interactive dynamic event-based models of surface mining operation is introduced. A discussion of logic diagrams for some selected events is also presented. In conclusion, a plan for future activities involving the use of computer models in both planning and decision-making is
described.
SF? tracer gas used to trace airflow through abandoned mine workings
Authors: Stokes A W
Published: September 2017

The tracer gas Sulphur Hexafluoride (SF?) was used to confirm the continued existence of the underground connection between two abandoned collieries in the Sydney Coalfield. This report outlines the investigation and the results obtained.
Gob leakage in 8 east at Lingan Colliery
Authors: Stokes A W
Published: September 2017

The high losses of ventilation air through 8 East's gob provided a good opportunity to perform a detailed ventilation survey in which the pressure profile and air leakages were measured. Some simple assumptions were made about the leakage flows so that
"equivalent resistances" of leakage corridors in the gob area could be calculated. These values lead to a better understanding of the leakage of air around the longwall district and of the consolidation and compaction which occurs in the gob. Some theories are developed to explain the large
variation in the resistance of the gob corridors. The future work which will to be conducted to confirm these theories is discussed.
The time studies of truck/shovel system at Highvale Mine in Alberta
Authors: Srajer V
Published: September 2017

A time study of the Highvale mine operation was under way during 1983. This report summarizes the travel times for four different types of off-highway trucks at the mine, evaluate truck performance, ton-kilometer-hour ratings for truck tires, fuel consumption,
dumping and loading times, etc. The travel times are evaluated for each truck, each group of trucks and for each pit operation separately. The data evaluated in this report will be used for validation of truck/shovel computer model, presently under development at the National Research Council in
Ottawa.
Strength log of an open borehole from index testing of cuttings
Authors: Cain P , O'Leary L S
Published: September 2017

A method of determining the strength log of an open borehole from the index testing of cuttings is described with an example from the Sydney Coalfield, Nova Scotia. Work currently in progress to assess this method as an alternative to testing of cored borehole
samples is described.
An analysis of air leakage through longwall wastes in Lingan Colliery
Authors: Hamilton D M , Stokes A W
Published: September 2017

In the Lingan Colliery ventilation air is lost through the caved wastes behind advancing longwall coalf aces. The airflow in the intake and return airways which service the face can be measured and the leakage determined. This paper presents an analysis of the
air leakage in Lingan Colliery's 4W longwall. Reynolds number of the leakage flow was calculated by two independent methods. One utilizes Kozeny's hydraulic model for flow through a porous medium and the other treats the caved gob area as a system of parallel smooth pipes. Both methods provide a
better understanding of the flow characteristics of the air leakage.
Auxiliary duct airflow determination in Lingan Phalen using SF?
Authors: Stokes A W
Published: September 2017

An experiment was conducted to compare the measurements of airflow in an auxiliary duct using a pitot tube and tracer gas. This report briefly describes the methodology and results of the test.
Evaluation of shovel/loader operation at Highvale Mine in Alberta
Authors: Srajer V
Published: September 2017

Site specific and also common operating practices applicable to shovel and loader operation at the Highvale mine in Alberta are summarized in this report. The production data of shovel and loader were also collected and are evaluated here. The summary of mine
data are evaluated and tabled to determine average cycle times, bucket fill factors, time to fill different trucks employed at the mine, their total productive and delay times. The bucket fill factors and correction factors for depth of cut and the swing angle were calculated. The shovel
availability and utilization data were evaluated and are presented in graphs, showing operating and delay hours for the fourteen months period. Several parameters needed in development of the shovel and loader computer simulation model were identified.