bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimal control of a viscous generalized θ-type dispersive equation with weak dissipation
Authors: Fan Guobing , Yang Zhifeng
Published: December 2020

In this paper, we investigate the problem for optimal control of a viscous generalized

θ

\theta

-type dispersive equation (VG

θ

\theta

-type DE) with weak dissipation. First, we prove the existence and uniqueness of weak solution to the equation. Then, we present the optimal control of a VG

θ

\theta

-type DE with weak dissipation under boundary condition and prove the existence of optimal solution to the problem.
(p,Q) systems with critical singular exponential nonlinearities in the Heisenberg group
Authors: Pucci Patrizia , Temperini Letizia
Published: December 2020

The paper deals with the existence of solutions for(p,Q)(p,Q)coupled elliptic systems in the Heisenberg group, with critical exponential growth at infinity and singular behavior at the origin. We derive existence of nonnegative solutions with both components nontrivial and different, that is solving an actual system, which does not reduce into an equation. The main features and novelties of the paper are the presence of a general coupled critical exponential term of the Trudinger-Moser type and the fact that the system is set inℍn{{\mathbb{H}}}^{n}.
The lncRNA UBE2R2-AS1 suppresses cervical cancer cell growth in vitro
Authors: Liu Chunyan , Li Huajun , Yin Qinan
Published: December 2020

Purpose

This study explores the effects and mechanisms of the long noncoding RNA (lncRNA) UBE2R2-AS1 activity in the cervical cancer development.

Methods

Thirty-four pairs of normal adjacent and cancer tissues were collected from cervical cancer patients. Pathology was evaluated by HE staining, and UBE2R2-AS1 expression was evaluated by in situ hybridization assays. HeLa and SiHa cells were respectively divided into negative control, pcDNA 3.1 vehicle control and lncRNA-expressing groups. Cell proliferation and apoptosis were measured by CCK8 expression and flow cytometry. The number of invading cells and the wound healing rate were measured by transwell and wound healing assays, respectively. Relative protein levels (caspase-3, caspase-8, MMP-2 and MMP-9) were measured by Western blot.

Results

Compared with adjacent normal tissues, UBE2R2-AS1 expression was significantly suppressed in cancer tissues correlated with the increasing stage. UBE2R2-AS1 suppressed cell proliferation and enhanced apoptosis, as well as decreased cell invasion and wound healing in cervical cancer cell lines. UBE2R2-AS1 overexpression significantly upregulated caspase-3 and caspase-8 protein expressions and significantly downregulated MMP-2 and MMP-9 protein expressions by Western blot.

Conclusion

UBE2R2-AS1 suppressed cervical cancer cell biological activities and might represent an antitumor factor in cervical cancer.
Die Mobilmachungs- und Kriegsvorbereitungen der Sowjetunion in den 1950er und 1960er Jahren
Authors: Uhl Matthias
Published: December 2020

Der Aufsatz möchte eine Antwort darauf geben, wie die Wirtschaftsplaner der Staatlichen Plankommission der UdSSR (Gosplan) die sowjetischen Streitkräfte im Kriegsfall mit den vom Militär geforderten Waffen und Rüstungsgütern ausstatten wollten. Gefragt wird deshalb, welche Mengen von welchen Waffen für den Ernstfall bereitzustellen waren. Zudem wird versucht festzustellen, ob die Mobilmachungsplanungen mit der Militärstrategie der Sowjetunion in den 1950er und 1960er Jahren übereinstimmten oder ob Rüstungsmanager und Militärs unterschiedliche Vorstellungen von einem künftigen Krieg und seiner Vorbereitung besaßen. In einem zweiten Abschnitt werden die Planung der materiellen Versorgung der Bündnispartner des Warschauer Vertrages mit der benötigten Bewaffnung im Ernstfall betrachtet. So wird beispielsweise untersucht, ob die Rüstungsindustrie der Sowjetunion in der Lage war, die Bündnispartner im Falle eines Krieges ausreichend mit Waffen und Gerät auszustatten. Abschließend widmet sich der Beitrag der Zivilverteidigung der UdSSR unter den Bedingungen eines allumfassenden Raketen-Kernwaffenkrieges.
Kriegs-BND: Planungen für die Mobilmachung des Bundesnachrichten-dienstes von 1953 bis 1968
Authors: Keßelring Agilolf
Published: December 2020

Der Bundesnachrichtendienst (BND) war im Untersuchungszeitraum 1953 bis 1968 ein Auslandsnachrichtendienst mit Fähigkeiten eines Militärnachrichtendienstes. Im Kriegsfall wäre dieser mobilisiert und seine Zentrale nach Spanien verlegt worden. Dieser »Kriegs-BND« wäre seinen Aufgaben nach ein Militärnachrichtendienst gewesen. Mit Aufbau der Bundeswehr wäre er auf über 12 000 Mitarbeiter aufgewachsen. Er wäre, in sechs jeweils von einem aktiven oder Brigadegeneral der Reserve der Bundeswehr geführten Abteilungen gegliedert sowie von Generalleutnant der Reserve Gehlen geführt, der amerikanischen CIA unterstellt worden. Dies zeigt, wie die Bundesrepublik Deutschland in der Nachkriegszeit für den potenziellen Kriegsfall Regelungen anstrebte, um trotz des angenommenen Verlustes weiter Teile des Staatsterritoriums ein Höchstmaß an staatlicher Souveränität zu bewahren.
S. Grovus und Aya Yani – Zwei verschwundene Konstantinopeler Kirchen
Authors: Effenberger Arne
Published: December 2020

This paper examines reports of Eremya Çelebi Kömürcüyan (1637 – 1695) and Luigi Fernando Marsili (1679/80 in İstanbul) on three churches still existing in the late seventeenth century. Their topographical informations are compared with early pictorial representations of Constantinople/İstanbul (Hartmann Schedel, 1493; Giovanni Andrea Vavassore, c. 1530/50; Onufrio Panvinio, 1600; Pîrî Reis, 16th century; Franceso Scarella, c. 1686) in order to check whether the churches can be identified with those depicted here. The church of Aya Yani (St John) mentioned by Eremya Çelebi must have been located south of the Stable Gate (Ahırkapı). Marsili describes a church near the Sultan’s stables and a further one inside the Seraglio Garden. The location of the stables can be determined using the İstanbul-view from Matrakçı Nasuh (1537). The church of Aya Yani and „the church near the stables“ must therefore be identical. In Schedel’s illustration, the church in the Seraglio is erroneously designated as S. Grovus, whereas on the Düsseldorf copy after Buondelmonti’s Liber insularum Archipelagi (1485/90) it is labelled s. Maria. The building can be identified with the church of the Theotokos of the Hodegoi Monastery. Regarding the church depicted on the vedute of Vavassore and Panvinio in the former area of the imperial palace, the thesis already established by Cyril Mango is maintained, according to which the remains of the Nea Ekklesia can be seen here. Little is known about the original form of the Nea Ekklesia, but there is evidence from written sources that it was erected above substructures with underground spaces that were open to the public. If the church that Eremya Çelebi saw south of the Stable Gate, while Marsili located it near the Sultan’s stables, can be identified with the Nea Ekklesia, as suggested in this essay, then considerable remains of the building must have been still present at the end of the seventeenth century.
Contesting Hyperglobal Framings: An Analytical Approach
Authors: Harvey Rachel
Published: December 2020

Since the term globalization erupted in public and academic discourses in the late-1980s, the hyperglobal perspective has been a prominent framing offered to understand global phenomena. Despite important challenges, it has remained extremely popular with its rhetoric exerting a powerful influence across the political spectrum, and in business and policy circles. This article argues that one reason for this durability is its inadvertent reproduction by the traditional understandings of “local” and “global” utilized in frameworks critiquing the hyperglobal perspective. More specifically, as scholars have noted, the global-local tends to be marked by dichotomous binaries and placed in a scalar hierarchy where the global overpowers the local. To side-step the issues emerging from the global-local approach, a conceptual rubric focusing on the “global-particular” relationship is offered as an alternative. This orientation helps prevent the importation of the dichotomous binaries and scalar hierarchies that reproduce hyperglobal imaginaries. As a result, it is easier to retain the complexity and contingency of global dynamics, and by extension, challenge hyperglobal framings. A case study of the global foreign exchange market is used to elaborate on the framework and to show why it provides a stronger point of departure for researching and theorizing globalization.
Outsourcing and Networking: Similar Trends in Local State-NPO Cooperation in Germany and China
Authors: Levy Katja , Ketels Anja
Published: December 2020

This paper presents results of a German-Chinese comparative research project on the provision of services by non-profit organizations (NPOs) in the field of migration. It argues that NPOs and local governments deploy similar strategies in their joint attempt to tackle social problems, regardless of their political backgrounds. From a top-down perspective German and Chinese local governments show similar outsourcing modes, while from a bottom-up perspective NPOs show similar practices of network governance.
Preparation and characterization of cellulose bromo-isobutyl ester based on filter paper
Authors: Wu Rina , Wang Qiuyu , Liu Huayu , Wang Gaosheng , Lu Peng
Published: December 2020

Cellulose bromo-isobutyl ester was prepared using filter paper as raw material through esterification reaction with 2-Bromoisobutyryl bromide (BIBB) in N, N-Dimethyl-formamide (DMF). Cellulose esters with different degree of substitution were obtained. FTIR result indicated the successful introduction of bromo isobutyryl group in cellulose to obtain cellulose ester (Cell-Br). The surface of modified filter paper become rough and grooves could be observed by SEM. The thermal stability of the cellulose ester decreased in comparison with unmodified filter paper. Besides, the hydrophobicity of the filter paper was improved and the water contact angle increased from 73.4° to 116.5° with increasing degree of substitution. The water vapor barrier property was improved by 26 %. Furthermore, it was also found the modified filter paper possessed antibacterial activity against S. aureus bacteria. The modified filter paper obtained could be potentially used in food packaging fields and the results provide a simple method to prepare functional filter paper.
Constructing subject-specific lists of multiword combinations for EAP: A case study
Authors: Khamkhien Attapol , Wharton Sue
Published: December 2020

This study combines a corpus-based approach and intuition-based judgements to develop a set of multiword combinations for research publications in academic journals. To obtain a representative sample, a corpus of four internal sections of 120 Applied Linguistics research articles indexed in the TCI (Thai Citation Index) database was systematically compiled and investigated. To identify n-grams which occur frequently in the corpus, a corpus-based approach was used. First, a list of 49 content-based strings, likely to be the most useful for pedagogic purposes, was derived. Based on their grammatical and semantic relationships, 3-grams were further investigated. For multiword sequences to occur frequently in the corpus, some pragmatic functionality is required which contributes to pedagogical use. Five EAP instructors were therefore invited to select the useful multiword combinations from the list of identified n-grams. A list of 289 phraseological patterns was finally created successfully. The list can provide additional evidence-based and corpus-informed instructional resources which support English teachers with the planning of lessons as well as materials design and development, particularly for advanced language courses which target scholarly writing.
The spatial conceptualization of time in Spanish and Chinese
Authors: Pamies-Bertrán Antonio , Yuan Wang
Published: December 2020

There is a general consensus about the existence of a cognitive transfer by which we conceive time in terms of space, witnessed by the recurrence of this metaphor in many languages. We can distinguish two theoretical trends in the treatment of this conceptual metaphor: those based on universalistic apriorisms and those based on more relativistic and empirical assumptions. While the first tend to extrapolate from English, reducing this metaphor to very few basic models with a natural motivation, the second privilege Amerindian languages, with empirical data which do not fit in such speculative universals. This contrastive work on the two typologically distant languages Spanish and Chinese confirms the cross-linguistic productivity of other space-to-time associations (reversed time, mirror time, vertical time, cyclic time). Though our results show more similarities than differences in the overall available inventory, some specific divergences between Chinese and Spanish are also noted.
Das semantische Potential der Idiome aus kognitiver Perspektive
Authors: Sulikowska Anna
Published: December 2020

Idioms are especially complicated language units from a semantic point of view. They are motivated, expressive, ambigue, imagic and imaginistic, and contain a semantic added value. This corpus-based research on idioms shows that their meanings are not as stable as it has been presumed until now and that dictionary definitions contain many shortcomings. The aim of this article is to reveal the semantic potential of idioms in use and to explain it from a cognitive perspective. It is argued that the semantic complexity of idioms results from two aspects: (i) their ambiguity based on interaction between the literal and the lexicalized meaning, (ii) their polylexicality – the semantic derivations can occur not only on the level of the word group but also concern the individual components. As this research shows, the most important mechanisms of meaning constitution are metonymy, metaphor and metaphtonymy.
Review on analytical methods for quantification of ADHD drugs in human biological samples
Authors: Sundari J. , Amuthalakshmi S. , Nalini C.N.
Published: December 2020

Attention deficit hyperactivity disorder (ADHD) is a common neuro-developmental disorder. The symptoms of ADHD include difficulty in attention, memory and impulse control. Many pharmaceutical formulations (stimulants and non-stimulants) are available on the market to treat ADHD symptoms. The most commonly used drugs for treatment are amphetamine, methylphenidate, atomoxetine, bupropion, guanfacine and clonidine. In the field of pharmaceuticals, bioanalysis is an important tool used for the quantification of drugs and their metabolites present in biological samples using various analytical methods. Although a number of analytical methods were reported for the quantification of these drugs in biological samples of experimental animals, due to species differences, it is important to develop analytical methods to quantify these drugs in human biological samples to aid forensic and pharmacokinetic studies. In this review, we compile the bio-analytical methods such as spectrophotometry, spectrofluorimetry, mass spectrometry, electrophoresis, liquid chromatography and gas chromatography used for the quantification of ADHD drugs in human biological samples such as blood, plasma, serum, oral fluids, sweat, hair and urine based on earlier published articles from various journals.
Harnack-type inequality for linear fractional stochastic equations
Authors: Boufoussi Brahim , Mouchtabih Soufiane
Published: December 2020

Using the coupling method and Girsanov theorem, we prove a Harnack-type inequality for a stochastic differential equation with non-Lipschitz drift and driven by a fractional Brownian motion with Hurst parameter

H
<

1
2

{H<\frac{1}{2}}

. We also investigate this inequality for a stochastic differential equation driven by an additive fractional Brownian sheet.
RAP-method (random perturbation method) for minimax G-filter
Authors: Girko Vyacheslav L. , Shevchuk B. V. , Shevchuk L. D.
Published: December 2020

The spectral equations for the minimax estimates of the parameters of some systems are obtained.
Therapeutic approaches on the interaction between SARS-CoV2 and ACE2: a biochemical perspective
Authors: Baskol Gulden , Mazicioglu Mumtaz M. , Özel Merve
Published: December 2020

The current conditions in the progression of the SARS-CoV2 pandemic changed the current scientific paradigm, and we now observe a novel rhythm and way of evaluating the collected information. Previous experiences in epidemics with similar viruses (viz., SARS-CoV1, and MERS-CoV) and collected information about the viral transmission and replication can be used to overcome the SARS-CoV2 pandemic. Although SARS-CoV2 emerged very recently, there are plenty of scientific studies about similar viruses to comment on the current situation. Inhibition of SARS-CoV2 spike protein activation, inhibition of virus endocytosis, using a soluble form of ACE2, peptide or non-peptide analogs of ACE2, and sustaining ACE2/Angiotensin-(1–7)/Mas receptor pathway activation can be proposed for use in therapeutic studies. In this review, the biochemical mechanism of SARS-CoV2 and ACE2 binding, virus-cell membrane fusion, and endocytosis of virus to host cells are discussed according to the currently available literature. The significant contribution of this review may be to provide useful information to researchers into the SARS-CoV2 outbreak.
Zion, Jakob und Abraham
Authors: Spieckermann Hermann
Published: December 2020

Ps 46–48, eine bewusst gestaltete Komposition, spiegeln den Weg der Zionstheologie in den Psalmen mindestens durch drei Jahrhunderte hindurch wider. Ps 48 wird als Hymnus auf Zion aus vorexilischer Zeit vor dem Einfluss der neuassyrischen Großmacht beurteilt, der in frühnachexilischer Zeit durch Ps 46 ein erläuterndes Vorwort erhalten hat. Dies ist nach der Katastrophe von 587/6 v. Chr. und dem anschließenden Exil als notwendig erachtet worden. Ps 46 wirbt im erschütterten Gottesvolk um neues Vertrauen, indem mit Jhwh Zebaoth der Titel »Gott Jakobs« verbunden wird, eine Erinnerung an die verheißungsvollen Anfänge des Gottesvolkes. In der Perserzeit ist später Ps 47 als weiteres Vorwort komponiert und dazwischen gestellt worden. Um Jhwh, den einzigen König, sind die Edlen aller Völker zum gemeinsamen Lob versammelt und empfangen den Ehrentitel »Volk des Gottes Abrahams«. In diesem Lichte kann der Kampf der Könige in Ps 48 gegen den Großkönig Jhwh nur noch als Ausnahme gegenüber der wechselseitigen Zuwendung von Jhwh und den Völkern erscheinen.
Three Evil Kings and One Promise: Another Look at the Doctrine of Retribution and the Question of the Eternal Reign of the Davidic Dynasty in the Book of Chronicles
Authors: Amar Itzhak
Published: December 2020

One of the most widely studied subjects in scholarship on the book of Chronicles is the question of the Eternal Reign of the Davidic dynasty. Most scholars have adopted the same methodic approach: analyzing sources in the book connected to the promise of the Davidic dynasty. This article addresses this issue from a novel angle–through a discussion of the three most wicked kings described in the book of Chronicles, Jehoram, Ahaziah, and Ahaz. It seems that the question whether the rule of a certain king, and the succession of his son after him, can be justified, arises only in cases where the king has no merits whatsoever. The comparison between these three kings uncovers numerous connections between them, especially the motif of the death of their children.
David und Moab – Eine schwierige Verhältnisbestimmung
Authors: Gaß Erasmus
Published: December 2020

Mit einer nördlichen Lage von Horonajim und einer Verbindung dieses Ortes mit der Daviddynastie (KAI 181:31) kann man einen historischen Kern der biblischen Texte bestimmen, die eine Beziehung Davids zu Moab behaupten. Die Dynastie Davids wäre somit von den Omriden im Ostjordanland eingesetzt worden, um einen Teil Moabs zu kontrollieren. Die biblische Erzählung hat die kriegerischen Erfolge des 9. Jh. v. Chr. mit David verbunden. Im Rutbuch könnte sich zudem die Tradition erhalten haben, dass die Daviddynastie irgendwann in Moab residierte und von dort wieder nach Jerusalem zurückgekehrt ist.
Narrative Mikrostruktur
Authors: Eckardt Regine
Published: December 2020

Text comprehension is based on the literal content of sentences and pragmatic enrichment. Theories of pragmatic enrichment in the literature include enrichment of narrative texts, but also pragmatic content conveyed by presupposition triggers. Taking texts by Ror Wolf as my test case, I illustrate that our capacity of pragmatic enrichment can be abused to understand paradoxical content, even though the literal content of the text seems coherent at the surface level. This shows that pragmatic enrichment in narration is a genuine part of language processing and must not be equated with commonsense reasoning.
In search of hyperchaos in a high dimensional unmagnetized quantum plasma
Authors: Mandi Laxmikanta , Natiq Hayder , Chatterjee Prasanta , Ali Rustam , Banerjee Santo
Published: December 2020

The hyperchaos and multistability of electron acoustic waves in a quantum plasma model comprising of nondegenerate cold and degenerate hot electrons and stationary ions are investigated. A six-dimensional dynamical system is constructed from the fluid equations of the model considering traveling wave transformation. The stability analysis of the system is done by finding out the equilibria in the inertia frame. It is interesting to investigate that though the novel system is conservative, it can produce hyperchaos for a set of associated parameters. We have also reported the coexistence of many hyperchaotic attractors as the system is extremely sensitive to the initials. The signature of hyperchaos and coexisting hyperchaos in a conservative quantum plasma system has never been reported before.
Pseudoaneurysm with Median Nerve Injury Caused by Right Radial Artery Puncture: A Case Report
Authors: Li Yachao , Xue Zengming , Ma He , Zhang Wei , Nie Shaoping , Ma Changsheng
Published: December 2020

Background: Pseudoaneurysm with median nerve injury is a serious complication of radial artery puncture. It is very important to summarize the prevention and treatment experience of this complication through case discussion.

Case report: A 66-year-old woman was admitted to the hospital because of “paroxysmal chest tightness and suffocation for 5 days.” Coronary angiography was performed. During insertion of the arterial sheath, the patient experienced severe pain in the right forearm, which radiated to the palm. The puncture sheath did not return blood after the sheath core was withdrawn. The sheath was removed and local compression was used to stop bleeding. There was no obvious bleeding at the puncture point, and the compression was removed 6 hours after the procedure. Local swelling and increased tension were seen in the right forearm. At the 1-week follow-up she exhibited swelling, high local tension, small blisters, and bluish-purple skin of the right forearm, with an acceptable right radial artery pulsation. She had severe pain in the affected limb, which radiated to the thumb, index finger, and middle finger.

Case discussion: We discuss the causes of and treatment measures for pseudoaneurysm with median nerve injury caused by radial artery puncture.
Semantic Dimensions of Sound Mass Music
Authors: Noble Jason , Thoret Etienne , Henry Max , McAdams Stephen
Published: December 2020

We combine perceptual research and acoustic analysis to probe the messy, pluralistic world of musical semantics, focusing on sound mass music. Composers and scholars describe sound mass with many semantic associations. We designed an experiment to evaluate to what extent these associations are experienced by other listeners. Thirty-eight participants heard 40 excerpts of sound mass music and related contemporary genres and rated them along batteries of semantic scales. Participants also described their rating strategies for some categories. A combination of qualitative stimulus analyses, Cronbach’s alpha tests, and principal component analyses suggest that cross-domain mappings between semantic categories and musical properties are statistically coherent between participants, implying non-arbitrary relations. Some aspects of participants’ descriptions of their rating strategies appear to be reflected in their numerical ratings. We sought quantitative bases for these associations in the acoustic signals. After attempts to correlate semantic ratings with classical audio descriptors failed, we pursued a neuromimetic representation called spectrotemporal modulations (STMs), which explains much more of the variance in semantic ratings. This result suggests that semantic interpretations of music may involve qualities or attributes that are objectively present in the music, since computer simulation can use sound signals to partially reconstruct human semantic ratings.
Beyond the IFIs, beyond USAID in Chavista Venezuela
Authors: Gill Timothy M.
Published: December 2020

Many scholars assert that the U.S. state promotes free market economic policies abroad through the leverage it wields within international financial institutions (IFIs), such as the International Monetary Fund and the World Bank. Other scholars have focused on U.S. bilateral aid programs, such as those implemented by USAID, and their emphasis on free market economic policies. In many middle-income countries, though, IFIs and U.S. development agencies do not maintain economic development programs. If the U.S. state cannot promote free market policies through IFIs and its bilateral development agencies, how does it promote them at all in middle-income countries? In this paper, I provide a case study of U.S. foreign policy toward Venezuela, a middle-income country, under the government of President Hugo Chávez (1999–2013). I draw on interviews with U.S. state elites, including several former ambassadors and State Department employees, and U.S. state documents to show how the U.S. encourages free market economic reforms through its support for civil society organizations that embrace these reforms. In particular, I focus on the work of the Center for International Private Enterprise, which has explicitly linked political freedom with economic freedom. Through this organization, the U.S. works with free market think tanks and promotes free market initiatives, all in the form of political rather than economic assistance.
Projection lateral bands and lateral retracts
Authors: Kamińska A. , Krasikova I. , Popov M.
Published: December 2020

A projection lateral band $G$ in a Riesz space $E$ is defined to be a lateral band which is the image of an orthogonally additive projection $Q: E \to E$ possessing the property that $Q(x)$ is a fragment of $x$ for all $x \in E$, called a lateral retraction of $E$ onto $G$ (which is then proved to be unique). We investigate properties of lateral retracts, that are, images of lateral retractions, and describe lateral retractions onto principal projection lateral bands (i.e. lateral bands generated by single elements) in a Riesz space with the principal projection property. Moreover, we prove that every lateral retract is a lateral band, and every lateral band in a Dedekind complete Riesz space is a projection lateral band.
EFFECT OF NATURAL AND SYNTHETIC PHYTOHORMONES ON GROWTH AND DEVELOPMENT OF HIGHER BASIDIOMYCETES
Authors:   Ukrainian State University of Chemical Technology, Dnipro, KUZNETSOVA O.
Published: December 2020

The paper is aimed to analyze the current data on the influence of exogenous growth stimulators on growth and development of higher Basidiomycetes. The historical aspects about discovery and role of phytohormones in fungi physiology are reviewed. The taxa of the basidiomycetes, which are capable of synthesizing phytohormones of all known types, including Aphyllophorales, Boletales, Agaricales, Sclerodermales, Hymenogastrales, Uredinales, Ustilaginales are described. The data from different sources describing the effects of natural and synthetic growth stimulators on the development of basidiomycetes are summarized and compared. It is noted that various concentrations of phytohormones (auxins, gibberellins, cytokinins) from 0.01 to 400 mg/ml were used in the experiments to study their effects on mycelial growth. Possible causes of conflicting results obtained by different authors, such as application of diverse methods of mushroom cultivation, different media and methods of substrate sterilization, are described.
RETINOIDS IN DERMATOLOGY:FUNCTIONAL ACTIVITY AND PROSPECTS OF SYNTHETIC ANALOGUES
Authors:   National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, KOVTUN V. B.
Published: December 2020

The aim of the work was to analyze and summarize information on the functional activity of known retinoids, as well as to determine the directions of their modification and prospects for the use of their synthetic analogues in dermatology. The literature on retinoids metabolism stages in the human body, the mechanisms of their action and the properties that determine their use in various medical fields was considered and analyzed. Information on dermatological diseases treatment with natural retinoids and their synthetic analogues was summarized. The modern classification of retinoids based on the peculiarities of their chemical structure and functional activity is given, the relationship between these characteristics and the direction of use of such drugs in dermatology and cosmetology is shown. Prospects for the practical application of synthetic retinoids represented mainly by polyaromatic compounds are due to their higher stability and efficiency, as well as reduced irritant effect due to selectivity for nuclear receptors.
INTERACTION OF OBLIGATE ANAEROBIC DESTROYER OF SOLID ORGANIC WASTE Clostridium butyricum GMP1 WITH SOLUBLE COMPOUNDS OF TOXIC METALS Cr(VI), Mo(VI) AND W(VI)
Authors:   Zabolotny Institute of Microbiology and Virology of the National Academy of Sciences of Ukraine, Kyiv, Hovorukha V. M.
Published: December 2020

Increasing pollution of environment by toxic metals is the urgent problem requiring effective solution worldwide. The goal of the work was to study the dynamics of the interaction of Cr(VI), Mo(VI), W(VI) compounds with obligate anaerobic microorganisms Clostridium butyricum GMP1, which ferment organic compounds with the synthesis of hydrogen. The standard methods were used to determine рН and redox potential (Eh), the gas composition, and the concentration of metals. The application Clostridium butyricum GMP1 was showed to be useful to investigate its interaction with toxic metals. The higher redox potential of metal provided the opportunity for its faster and more effective reduction. The patterns of the reduction of toxic metals Cr(VI), Mo(VI) and W(VI) by obligate anaerobic strain Clostridium butyricum GMP1 were obtained. The experimental data confirmed the thermodynamically calculated correlation between the redox potential of the metal reduction to insoluble form and effectiveness of its removal. Obtained results can serve as the basis for further optimization and development of environmental biotechnologies for wastewater treatment with the simultaneous destruction of solid organic waste and hydrogen synthesis.
Strategic Approaches to Activating Academic Entrepreneurship in Modern Mega-Universities: Prospects for Ukraine
Authors:   Taras Shevchenko National University of Kyiv, Novikova I.E. , Zhylinska O.I. ,   Taras Shevchenko National University of Kyiv, Osetsky V.L. ,   Taras Shevchenko National University of Kyiv, Bediukh O.R. ,   Taras Shevchenko National University of Kyiv
Published: December 2020

Introduction. Currently, R&D activity is the main in all the top universities in the world because it is focused on the acquisition of new knowledge, while educational is only on the use of acquired knowledge. However, in Ukraine, the trend of academic entrepreneurship development has not yet taken on proper significance. Problem Statement. The implementation of the idea of intensifying the innovation-investment movement in Ukrainian universities involves upgrading the existing innovation-oriented infrastructure and developing an effective plan of action for those universities in which material and technical and intellectual foundation till have a well-preserved. Purpose. formulate strategic approaches to the commercialization of research products in modern mega-universities, which generally involves the intensification of research activities in the context of international academic entrepreneurship education as an imperative for the development of a high-tech, export-oriented and socially responsible model of economy. Materials and Methods. The methods of economic (in particular PEST- and SWOT-analyzes) and logic-structural analysis, methods of comparison, synthesis, forecasting, theoretical generalization, as well as economicstatistical methods of analysis of actual data are used. Results. A result of this initiative is to formulate recommendations and steps to increase the non-budgetary sources of funding for university research and innovation activities in Ukraine, in particular by raising the profitability of intellectual property and the creation of small innovative enterprises. Conclusions. The results obtained will allow us to formulate strategic principles in the development of a new methodological paradigm for the commercialization of the results of intellectual work in universities, taking into account the development trends of the world and the features of national science.
Modeling Communication Between the Public and the Authorities while Implementing Innovative Projects in the Context of E-Democracy and Public Administration
Authors:   Vinnytsia National Technical University, Shyian A.A. , Azarova A.O. ,   Vinnytsia National Technical University, Nіkіfоrоvа L.O. ,   Vinnytsia National Technical University, Tkachuk L.M. ,   Vinnytsia National Technical University, Azarova V.V. ,   Vinnytsia National Technical University
Published: December 2020

Introduction. E-democracy and e-government become an increasingly common attribute of people's lives, since they give is an opportunity to attract population masses to the discussion of both economic and social, as well as managerial innovations. The society urgently requires innovation in the organization of public and regional administration. Problem Statement. Adjemoglu and Robinson have shown that the necessary factor for the success of public or region development is the presence of inclusive political and economic institutions. Inclusive institutions involve the widest possible population in decision-making. Moreover, namely the political institutions (which are crucial for involving as much as possible the public to making decision) determine successful development of society. Innovative projects are the driver of economic development, so the involvement of the general public in their discussion, decision-making, implementation and analysis of the results is an extremely important factor. Many authors have emphasized that the digitalization of information is an important factor for the formation and development of a developed society. Purpose. The purpose of this research is to develop approaches to modeling the communication channels of the public and authorities under the conditions of innovation project implementing in the context of e-democracy and public administration. Materials and Methods. The research uses the methods of system analysis, game theory, structural, functional, and logical analysis. Results. Innovative projects are supported primarily by the middle class, as evidenced by the Hotelling model (the median voter model). The analysis of existing in Ukraine functional model of communication between the public and the authorities while implementing innovation projects has revealed a number of its shortcomings. To correct them, a scheme for optimizing the communication between the authorities and the public by means of e-democracy while implementing an innovation project has been proposed. The necessity of attracting media, experts, and analysts at each stage of the implementation of the innovation project has been justified. Conclusions. The described communication channel includes electronic media and the community of experts and analysts as compulsory components. It enables the creation an effective system of feedbacks between the authorities and the public which allows making optimal decisions and monitoring the socio-economic development of society.
Object Relations as “Whole General Effect” in Management
Authors:   National University of Bioresources and Use of Natural resources of Ukraine, Morozov O.F. , Shevchenko M.M. ,   Presidium of the NAS of Ukraine
Published: December 2020

Introduction. The socio-economic structure and the structure of economic production in Ukraine are get increasingly subjected to the consumption of goods and services. Problem Statement. In the outlined conditions, the problem is that in most cases, the economy has been already controlling the human being, not vice versa. Purpose. The development of a systematic approach to the problem of revealing the essence of the relationship between the “subject” of economic space management, the human being, and the “object” of management, the economic space, in order to find ways to return to human-centered socio-economic structure of the country. Materials and Methods. For the first time, a new concept of “social effect” has been introduced. It is an analog of the well-known lexicographic effect proposed at the beginning of the 21st century by Full Member of the NAS of Ukraine V. Shirokov, which may be regarded as a phenomenological framework of the theory of complexity and the corresponding specific theory of economic information, on the one hand. On the other hand, the complexity theory, the Kolmogorov information, and the Levenheim-Skolem theorem may be considered formal correlates of the lexicographic effects in economic systems. Results. This approach is considered system-creating to describe the holistic processes of relations of economic systems of five levels with the phenomenal property of self-compensation of complexity. The separation of structural, substantive, and subjective properties, as well as the relationships between them gives the analyzed economic reality the property of being a system. Conclusions. Based on the above assumptions and general theoretical and informational ideas about socio-economic systems of five levels as formal correlates of the lexicographic effect, it has been proposed to coordinatize and to unify information in the economic space of these management systems as a basis for establishing the “source — form — content” equilibrium in accordance with the rule of "common goals".
The Policy of Village Web-Based Land Affairs Administration Management as Prior Evidence in Land Registration in Indonesia
Authors: Yulianti Rina , Ikhwan Mufarrijul
Published: December 2020

Indonesia has not had good land affairs administration management yet at Village Government Level. Land conflict or dispute derives from village’s very limited, manual, and outdated data. Data at village level still refers to data inherited from East Indie government time. The data available cannot meet the modern need today. Relatively inadequate human resource at village level and low awareness of land affair administration discipline within society make the change of prior data supply difficult. This research will study the utilization of village web in providing prior evidence of land registration and the juridical construction of web-based land affairs administration management to the organization of village government. The normative juridical research method with statute and conceptual approaches was used to address the problem of research. The result of research showed that the data of land affairs presented by village web can be the prior evidence as governed in Government Regulation about Land Registration and the provision without changing the source of evidence that can be either written evidence or testimony. The juridical construction of village web-based land affairs administration management derived from Village Law, Archive Law, and Information and Electronic Transaction Law. Village government can present the web-based land affairs data and make it electronic evidence. Keywords: Management, Administration, Land Affairs, Village Web
Reconstruction to Prove Elements of Detrimental to State Finances in the Criminal Act of Corruption in Indonesia
Authors: Firmansyah Firmansyah , Santoso Topo , Febrian Febrian , Nashriana Nashriana
Published: December 2020

State financial loss is one of the elements of the criminal act of corruption in Article 2 paragraph (1) and Article 3 of Law No. 31 of 1999 in conjunction with Law No. 20 of 2001 concerning the Eradication of Corruption Crime. The formulation of the element of detrimental to state finances in the two articles at the level of evidence still raises various obstacles because it is an obscure norm and is multi-interpretative in nature. The results of the research show that proving that the element of detrimental to state finances in the criminal act of corruption is still understood as a formal crime so that the proof is sufficient by fulfilling the act and there is no need for consequences, whether potential loss of state finances or actual loss, the perpetrator can be convicted. After the Constitutional Court through its decision Number 25/PUU-XIV/2016 stated that the word "can" in Article 2 paragraph (1) and Article 3 is unconstitutional and has fundamentally changed the qualification of corruption to become a material crime, but in its application there are different views of law enforcement officials in proving that the element is detrimental to state finances, giving rise to legal uncertainty. In the upcoming reform of the criminal law of corruption, a more appropriate model of proof is to use the concept of state financial loss in the sense of material crime. Through this concept, a new act can be seen as fulfilling the elements of a corruption crime on the condition that there must be an effect that the state loss is real and occurs (actual loss). The concept of proving state financial losses in a material sense ensures fair legal certainty. Keywords  : Reconstruction, Evidence, State Financial Losses, Corruption Crime.
Foreign Science of Administrative Law and Possible Areas of Its Adaptation in Ukraine
Authors: Haran Olha Volodymyrivna , Maksimentseva Nadiia , Кhrystynchenko Nadiia , Povydysh Vladyslav Volodymyrovych
Published: December 2020

AbstractThe purpose of the article is to study the foreign science of administrative law and to determine certain areas of its adaptation in Ukraine. To achieve this purpose, we have used such methods of scientific cognition as: dialectical, historical, formal and logical, system and structural. The authors of the article have studied the content and specific features of foreign administrative and legal science, as well as have suggested possible ways to implement it into scientific and legal system of Ukraine. It has been stated that the effective development of the national system of public administration is impossible without the quality functioning of science, which deals with studying forms and methods of administration, and an effective management system is essential for the success of any country. It has been noted that in order to achieve high results in the work of state agencies, their staff must be well educated on the use of optimal forms and methods of administration activity. Professionals who represent the state or local self-governments while performing their professional duties must have all the necessary skills (means) to achieve the tactical and strategic objectives set before them. The leadership of such agencies must be able to think globally and be able to set specific and objective tasks, as well as to provide the most effective means for their implementation. The historical aspects of the formation and development of administrative and legal science as a key element of administrative system in different countries have been studied. Keywords: Administrative Law, Legal Regulation, Administrative and Legal Science, Administrative Activity, Legislative Provision.
Criminological Study of Domestic Violence in Iran
Authors: Ziya Rashin , Ahmadi Ahmad
Published: December 2020

Violence against women is a common and unfortunate phenomenon whose widespread dimensions cause a lot of personal and social harm to them, family and society. This study was conducted by library method. The study was performed aimed at investigating the violence against women in Iranian society with a criminological approach. Many women have traditionally accepted some violence or are unaware that it is violent because the law does not criminalize it and has the support of custom and religion to legitimize it. In this study, the types of domestic violence and its examples that occur against women and most of them may not even be considered violent were first mentioned. Moreover, legal and criminal laws effective in creating or exacerbating violence against women and the role of common traditions in Iranian culture as well as harmful customs and habits were examined. Women's rights organizations argue that legal weaknesses need to be addressed and eliminated, and that governments should to be encouraged to comply with the law and change inappropriate laws. At lower levels, violence against women must be curbed socially by helping to grow women's NGOs, and thus raising women's awareness of their rights to violence. However, the presence and role of men in eliminating violence against women is essential, and violence cannot be eradicated without the cooperation of men. Men must also be forced to break their silence and enter this arena.Keywords: domestic violence, criminology, domestic violence.