bluuebunny/crossref_metadata_2025 huggingface dataset:
STRUCTURES AND FUNCTIONS OF PENLECTINS AND THEIR INVOLVEMENT IN GASTROINTESTINAL IMMUNE SYSTEM OF BLACK TIGER SHRIMP Penaeus monodon
Authors:   , Angthong Pacharaporn
Published: November 2023

Tachylectin5A and Tachylectin5B, both contain a fibrinogen-related domain (FReD) and have been studied in japanese horseshoe crabs, Tachypleus tridentatus and shown to be involved in host defense. Here, we demonstrate the presence of tachylectin5- like genes in the shrimp, P. monodon, which we have named as Penlectin5-1 (PL5-1), Penlectin5-2 (PL5-2) and Penlectin5-3 (PL5-3). All three lectins contain a signal peptide and a single FReD with an acetyl group and a calcium binding sites. They are structurally similar to japanese horseshoe crab tachylectin5. The PL5-1, PL5-2 and PL5-3 transcripts were expressed in various shrimp tissues in normal shrimp, and its expression was up-regulated in tissues such as hemocytes, posterior intestine or stomach following challenge with pathogenic V. harveyi or V. parahaemolyticus (3HP). The PL5-1, PL5-2 and PL5-3 proteins were expressed in a bacterial expression system and they were expressed as non-soluble proteins. Only the PL5-2 protein was possible to isolate and purify from shrimp plasma using affinity chromatography, and therefore, the PL5-2 protein was used for functional studies of this protein. The PL5-2 protein was detected in various tissues as well as in cell-free hemolymph. The biological function of the PL5-2 protein is to recognize some Gram-positive and Gram-negative bacteria regardless whether they are non-pathogenic or pathogenic. This lectin had hemagglutination activity towards all types of human erythrocytes including A, B and O type, and it had also a bacterial agglutination activity to both Gram-negative and Gram-positive bacteria. Possible binding sites of PL5-2 to bacteria could be at the N-acetyl moiety of the GlcNAc-MurNAc cell wall of the peptidoglycan, since the binding could be inhibited by GlcNAc or GalNAC. To further understand the functions and the involvements of PL5-1, PL5-2 and PL5-3 in response to AHPND in shrimp, knockdown of the PL5 genes using RNAi was performed prior to an oral administration of Vibrio parahaemolyticus (VP3HP) causing AHPND. The results suggest that PL5-1, PL5-2 or PL5-3 silencing in shrimp challenged with VP3HP showed higher increases in mortality as well as more severity of histopathological changes. The presence of PL5-2 protein in both circulating hemolymph and gastrointestinal tract, where host and microbes are usually interacting, may suggest that the physiological function of shrimp tachylectin-like proteins is to recognize and bind to invading bacteria to immobilize and entrap these microbes and subsequently clear them from circulation and the host body. It is also probably possible that the Penlectins are involved in controlling and maintaining the normal flora in the intestine.
Development of paper-based devices for detection of Vibrio parahaemolyticus DNA from loop-mediated isothermal amplification
Authors:   , Tipchote Jutaporn
Published: November 2023

Vibrio parahaemolyticus (V. parahaemolyticus) is a gram-negative, halophilic marine bacterium and marine seafood-borne pathogen causing gastrointestinal disorders to humans. In this work, colorimetric paper-based device was employed for the determination of V. parahaemolyticus DNA amplified by loop-mediated isothermal amplification (LAMP). LAMP was performed using a set of six specially designed primers which is specific to V. parahaemolyticus DNA. The optimal isothermal amplification was at 65°C for 45 min. After DNA amplifyed by LAMP, colorimetric assay was carried out on paper-based device for DNA determination using silver nanoparticles (AgNPs) as colorimetric agent. It was found that the color of AgNPs did not change in the presence of amplified DNA, whereas color of AgNPs changed from yellow to red in the presence of unamplified DNA. The results of the assay can be easily evaluated by naked eyes.  The limit of detection (LOD) was found to be 11.15 CFU mL-1. Therefore, the developed method was used for the determination of V. parahaemolyticus DNA in seafood (shrimps and oysters). Comparison of the results obtained from this proposed method to those obtained by the plate count method (TCBS) and LAMP-gel electrophoresis proved that this developed method has good agreement with the conventional method in terms of accuracy for practical applications. Hence, LAMP-AgNPs on PADs serves as a rapid, inexpensive and simple assay without the need for complicated instrumentation.
MORPHOPHONEMIC ALTERNATIONS OF EKEGUSII NOMINAL DERIVATION: AN OPTIMALITY APPROACH
Authors: Everlyne Onkwani
Published: November 2023

The study examined the morphophonemic alternations in derivation of nouns in Ekegusii to describe the types of derived nouns, the phonological processes involved in the nominal derivation and to formulate phonological constraints of prefixation. A descriptive research design was employed to collect, analyze and describe data. A list of 50 derived nominal was generated, Rogooro dialect speakers of Ekegusii in Moi University were identified to verify data. Sample data were obtained from each noun class through purposive sampling which were analyzed and coded into semantic classes and explained using Transderivational AntiFaithfulness (TAF) Theory. Findings of the study indicate that nominal derivation forms deverbal, deadjectival, diminutive and abstract nominals. Noun Class prefixes induce vowel deletion, alternation and lengthening, consonant mutation, deletion and nasal assimilation because of unfaithful mappings of inputs to the outputs as a result of the interaction of markedness and faithfulness constraints in Optimality and TAF Theories.
WOKENAM: JUAN'S NEW DOGMA
Authors: R. Parrucho Rowella , M. Francisquete David Francis , E. Gulle Kaye Marie , A. Saberon Guile
Published: November 2023

The call to stay woke emerged in the early 19th century as a metaphor for social justice. However, despite early exposure, this globally perceived culture was obscured in some communities. The proponents utilized Creative Research and interviewed active individuals in this echo chamber: one public historian and a professor, one journalist who writes primarily on pop culture to debunk the roots of this culture, and five participants from different universities and organizations in the Philippines who are actively participating in the social and political discourses. The researcher found that the term woke is more prevalent within left politics while the critics are right-winged. However, both could be a target, especially if their political stance no longer favors the government. With the help of existing studies and respondents, the proponents have magnified the idea; contrary to the widespread presumptions, the wokeness of Filipinos is the effect of social realities, and activism is a norm in such culture. Furthermore, the creation is apparent in Philippine democracy; it has been subject to democratic pitfalls because of political polarization resulting from canceling culture. Today, slang embraces progressive activism and is evident in our information ecosystems. This study is vital to human society regardless of their stance and affiliated circle.
Definitional Problems, Indefinite Solutions: Revisiting the ICC's Conception of Gender in a Gender-Critical World
Authors: Lasharie Neiha
Published: November 2023

Article 7(3) of the International Criminal Court’s Rome Statute defines gender as “the two sexes, male and female, within the context of society.” It further notes that “‘gender’ does not indicate any meaning different from the above.” The product of heated negotiations between States, this definition reifies a binary view of gender, excluding from the court’s ambit whole swaths of people who do not conform to simply male or female. This Comment argues that revisiting the definition of gender is necessary in an increasingly transphobic world where violence against gender variant persons is reaching a fever pitch. Such violence may rise to the level of gender persecution—a crime against humanity—if not worse. This Comment traces the history of negotiations on Article 7(3) of the Rome Statute, identifies three approaches towards the “gender” question, and suggests a path forward. For the court to truly hold perpetrators of crimes accountable, it cannot hold to such a narrow, exclusionary understanding of gender.
Profiling, Targeting, Algorithmen, künstliche Intelligenz – über die Irrwege einer Debatte in der Arbeitsmarktpolitik
Authors: Bachberger-Strolz Kerstin
Published: November 2023

Der Text behandelt die Möglichkeiten und Grenzen von Profiling in der Arbeitsmarktpolitik: Ausgehend von den Erfahrungen in den USA seit den 1990er Jahren wird gezeigt, dass beim Profiling viele Probleme seit Beginn ungelöst blieben, wie etwa die fehlende Schätzgenauigkeit, der geringe Nutzen von Profiling-Ergebnissen für die Zuweisung zu Programmen, die Widerstände von BeraterInnen, etc. Damit bleibt die zentrale Erkenntnis für die österreichische Arbeitsmarktpolitik, dass Profiling für das Targeting beim AMS wenig hilfreich ist. Über die genannten Problem hinaus muss festgehalten werden, dass mit der intransparenten Vorgangsweise des AMS und mit der Wahl des Unternehmens, das Profiling im AMS entwickeln und implementieren soll, der Sache des Profiling kein guter Dienst erwiesen wurde. Daraus folgt, dass die österreichische Arbeitsmarktpolitik besser heute als morgen den unglücklichen Versuch der Implementierung von Profiling beenden sollte.
Geschlechtsspezifische Pensionslücke in Österreich
Authors: Mayrhuber Christine
Published: November 2023

Österreich ist gekennzeichnet durch mehrere geschlechtsspezifische Nachteile („Gender Gaps“). Zum einen haben wir im europäischen Vergleich einen überdurchschnittlich hohen Gender Pay Gap: Abhängig von den verwendeten Einkommensdaten liegt er zwischen 15,6% (bereinigte Stundenlöhne, 2015) und 36,7% (unbereinigte Jahreseinkommen, 2018).
Zum anderen ist auch der Versorgungsgap, also der geschlechtsspezifische Unterschied bei den Anteilen von Personen im Pensionsalter mit autonomen Pensionseinkommen, hoch: 11,4% der Frauen haben keine eigenständigen oder abgeleiteten Alterseinkünfte (Männer: 1,3%), der Versorgungsgap der Frauen im Pensionsalter liegt damit bei 10,1 Prozentpunkten. Schließlich beträgt der Pensionsnachteil, der Gender Gap bei Pensionen (kurz GGP) für Frauen, die 2019 in eine Alterspension übertraten, im Durchschnitt 39,4% und im Median 46,1%. Vergleichbare europäische Zahlen aller Alterseinkommen der 65- bis 79-Jährigen weisen den österreichischen Pensionsgap mit 38,8% aus, er liegt um 9,7 Prozentpunkte über dem EU-28-Schnitt. Hauptursache des GGP ist in erster Linie das geringe Erwerbseinkommen und in zweiter Linie die geringere Anzahl an Versicherungsjahren von Frauen. Eine forcierte Gleichstellung am Arbeitsmarkt, allen voran bei den Erwerbseinkommen, ist somit die Grundvoraussetzung für eine Verringerung des frauenspezifischenPensionsnachteils.
CO2-relevante Besteuerung und Abgabenleistung der Sektoren in Österreich
Authors: Schnabl Alexander , Gust Sarah , Mateeva Liliana , Plank Kerstin , Wimmer Lorenz , Zenz Hannes
Published: November 2023

Das Ziel der vorliegenden Studie ist die Untersuchung des österreichischen Steuer- und Abgabensystems im Zusammenhang mit CO2-Emissionen. Ein zusätzlicher Fokus liegt dabei auf entsprechenden Steuerbefreiungen, Förderungen und Subventionen, die den CO2-Ausstoß in Österreich monetär begünstigen. Methodisch kommt eine um Umweltfaktoren erweiterte Input-Output-Analyse zur Anwendung. Als Datenbasis dienen die Energiebilanzen, die Luftemissionsrechnung, Förderberichte des Bundes und verschiedene Vorgängerstudien. Die Studie ist in drei Teile unterteilt. Der erste Teil befasst sich mit den bereits existierenden direkten Steuern und Förderungen. Dabei liegt ein starker Fokus auf der unterschiedlichen Verteilung zwischen den Wirtschaftssektoren und den Haushalten. Die Analyse zeigt, dass Letztere einen Großteil (5,3 Mrd. Euro) der CO2-relevanten Steuern und Abgaben bezahlen, während der Unternehmenssektor weitaus geringer belastet wird (3,5 Mrd. Euro). Darüber hinaus sind die existierenden Subventionen so ausgestaltet, dass hauptsächlich die Unternehmen davon profitieren (2,67 Mrd., Haushalte 0,65 Mrd. Euro). Der zweite Teil erweitert den ersten Teil um die sogenannten indirekten Effekte, indem auch die Steuerbelastung über die Vorleistungsverflechtungen in den einzelnen Sektoren mit in die Analyse genommen werden. Sowohl in der direkten, als auch in der indirekten Betrachtung zeigt sich, dass sich die Steuerlast deutlich zugunsten der Unternehmen über die Sektoren verteilt. Die Haushalte tragen die Hauptlast der existierenden CO2-relevanten Steuern und Abgaben, während sie von Förderungen kaum profitieren. Im Schnitt zahlen die Haushalte 127 Euro pro direkt verursachter Tonne CO2, während die Unternehmen nur 41 Euro zahlen. Im dritten Teil werden drei fiktive CO2-Steuerszenarien für Österreich berechnet. Werden die gesamten CO2-Emissionen als Berechnungsbasis herangezogen, so würde in der kurzen Frist die Steuerlast verglichen mit den existierenden Energiesteuern je nach Szenario um 2,2 Mil., 5,2 Mil. oder 6,9 Mil. Euro ansteigen. Werden nur die klimaschädlichen Emissionen als Berechnungsbasis einer Steuer herangezogen, so verringert sich die Steuerlast je nach Szenario auf 1,5 Mrd., 3,1 Mrd. oder 3,4 Mrd. Euro. Die Haushalte würden in allen Szenarien die Hauptlast tragen, auch wenn die indirekten Effekte betrachtet werden.
Die Verteilungseffekte einer CO2-Bepreisung im Haushaltssektor: Ein systematischer Überblick über die bestehende Literatur
Authors: Bernhofer Dominik
Published: November 2023

Die Verteilungswirkung einer CO2-Bepreisung und der damit verbundenen Rückerstattung der Einnahmen an die Wirtschaftsakteure ist eine der zentralen Fragen der Ökologisierung unserer Steuersysteme und der Klimapolitik insgesamt. Der vorliegende Artikel versucht auf Basis der bestehenden Literatur, mit speziellem Fokus auf Österreich, die wesentlichen Verteilungseffekte und -kanäle systematisch zu diskutieren. Dabei wird insbesondere zwischen den statischen Verteilungseffekten auf Basis konstanter Einkommen und Warenkörbe und den dynamischen Verteilungseffekten unter Berücksichtigung der Anpassungsreaktionen unterschieden. Die Analyse zeigt, dass die statischen Verteilungseffekte einer CO2-Bepreisung für Österreich klar regressiv sein dürften, der Gesamteffekt aber stark von der gewählten Art der Rückerstattung abhängt. In dynamischer Hinsicht ist ein Rückgang der Steuerbelastung über die Zeit durch Verhaltensanpassungen zu erwarten. Die regressiven Verteilungseffekte könnten sich über die Zeit aber noch verschärfen, weil die Verhaltensanpassungen zB der Heizungstausch nicht für alle Einkommensgruppen gleich erschwinglich sind.
 
Abstract
The distributional effects of carbon pricing the associated revenue recycling to economic agents is one of the central questions of ecological taxation and climate policy more generally. Based on the existing literature with a special focus on Austria, this article tries to provide a systematic discussion of the central distributional effects and channels. Thereby, the article distinguishes between static distributional effects, given constant household incomes and consumption baskets and dynamic distributional effects, taking behavioural responses into account. The analysis shows that a carbon price for Austria has regressive distributional consequences, whereby the overall effect crucially depends on the form of revenue recycling. From a dynamic perspective, the tax burden should diminish over time due to behavioural responses. The regressive distributional effects however could increase as behavioural responses like changing heating systems are not equally affordable for all income groups.
Angebot an Öffentlicher Kinderbetreuung und Einkommenseinbussen bei Mutterschaft
Authors: Zweimüller Josef , Kleven Henrik , Landais Camille , Posch Johanna , Steinhauer Andreas
Published: November 2023

Der Artikel diskutiert den Effekt der Ausweitung des Angebots an öffentlicher Kinderbetreuung auf den child penality, die Einkommenseinbussen bei Mutterschaft. Die hier präsentierten Ergebnisse basieren auf der Arbeit von Kleven, Landais, Posch, Steinhaer und Zweimüller (2020), welche den Effekt der Familienpolitik auf diese Einkommenseinbussen untersucht. Diese Studie kommt unter anderem zum Ergebnis, dass der starke Ausbau öffentlicher Betreuungsangebote für Kinder im Vorschulalter (Kindergrippen und Kindergärten) sich nicht in einer Reduktion des child penalty niedergeschlagen hat. Das Ziel der vorliegenden Arbeit ist eine leicht zugängliche Darstellung dieses Ergebnisses sowie der zugrunde liegenden Messkonzepte und Methoden. Am Ende der Arbeit zeihen wir Schlussfolgerungen für die Familienpolitik.
Grundlagen feministischer Ökonomie: Silvia Federicis zentrale Texte aus 40 Jahren.
Authors: Schultheiss Jana
Published: November 2023

Buchbesprechung von Silvia Federicis "Revolution at Point Zero. Hasurabeit, Reproduktion und feministischer Kampf". Im Jahr 2012 hat Federici zentrale Texte ihrer Arbeit, die zwischen 1975 und 2010 veröffentlicht wurden, in einem Sammelband herausgegeben. Dieser ist 2021 im UNRAST Verlag im Rahmen der Reihe „Theorien und Kämpfe der sozialen Reproduktion“ auf Deutsch erschienen. Gegenüber der ersten Ausgabe wurde der Band um drei Beiträge aus den Jahren 2011 und 2016 ergänzt. Der Sammelband ist in drei Abschnitte untergliedert: 1) Theorie und Politik der Hausarbeit, 2) Globalisierung und soziale Reproduktion, 3) Die Commons reproduzieren.
Die Europäische Mindestlohnrichtlinie – Paradigmenwechsel hin zu einem Sozialen Europa
Authors: Müller Torsten , Schulten Thorsten
Published: November 2023

Die Mindestlohn-Richtlinie gehört zu den wichtigsten arbeits- und sozialpolitischen Maßnahmen, die auf europäischer Ebene verabschiedet wurden. Sie kann zu einem Gamechanger im Kampf gegen Erwerbsarmut und soziale Ungleichheit werden. Sowohl durch Maßnahmen, die auf ein angemessenes (gesetzlichen) Mindestlohnniveaus abzielen, als auch jene die eine Stärkung der Tarifverhandlungen fördern. Der erhebliche Legitimationsverlust des europäischen Integrationsprojekts in der europäischen Bevölkerung hat dabei eine wichtige Rolle gespielt. Die Kommission hat erkannt, dass sie mit dem Krisenmanagement 2008/2009 den neoliberalen Bogen überspannt hat und dass maßgebliche Korrekturen notwendig sind, um der europakritischen Stimmung zu begegnen. Auch die Konstellation im Rat trug dazu bei; einerseits wollte die französische Regierung die Mindestlohn-Richtlinie noch während ihrer Ratspräsidentschaft abschließen, andererseits stellte der Regierungswechsel in Deutschland die Weichen dafür, dass die die Richtlinie sicher ins Ziel gelangte. Die konkrete Bedeutung der Mindestlohn-Richtlinie entscheidet sich letztlich in ihrer Umsetzung auf nationaler Ebene. Sowohl in Ländern mit gesetzlichen als auch in jenen mit tarifvertraglich festgelegten Mindestlöhnen.
Postkeynesianismus: Eine Einführung
Authors: Marterbauer Markus
Published: November 2023

John E. Kings Standardwerk über den Postkeynesianismus ist nun auf Deutsch erschienen. Es bietet einen exzellenten Überblick über die zentralen Elemente der Theorie, die Abgrenzung zu anderen ökonomischen Lehrmeinungen und Ansatzpunkte für eine moderne Wirtschaftspolitik.
Manual de Sutura - Edição I
Authors: Alisson Melo de Souza Borges John , Yasmin mapurunga perdigao Ana , Villena Teixeira Santos Silva Paula , Veras Araujo Santos Rodrigo , Alves Melquiades de Lima Marília , neves Mont’Alverne Napoleão Raffaela , Diógenes Queiroz Luísa , de Melo Desiderio Miguel , Hellen Pedrosa Souto Geovanna , Christina Botelho Dantas Marília , Coelho de Souza Júnior Klayton , Rafaella Cavalcante de Oliveira Zuila , Anne Melo Albuquerque Jullie , Maurício Muniz Rodrigues Cláudio
Published: November 2023

Este livro foi concebido pela Liga Acadêmica de Cirurgia Plástica da
Unichristus (LIPLAST), possui caráter didático e educativo, integrando o
conhecimento adquirido nas disciplinas de anatomia, fisiologia e técnica
operatória à vivência prátic
D-Day: going on the offensive over public access
Authors: Taylor Mike
Published: November 2023

A few weeks ago, software developer and pioneering blogger Joel Spolsky made an important point about SOPA/PIPA which has stayed with me: And of course the same thing applies to the RWA.
Sideshow Collectibles Apatosaurus maquette, Part 4: body, tail, limbs, base, and skull
Authors: Wedel Matt
Published: November 2023

This is the fourth in a series of posts in which I review the  Apatosaurus  maquette from Sideshow Collectibles. Other posts in the series are: Part 1: intro Part 2: the head Part 3: the neck Part 5: posture Part 6: texture and color Part 7: verdict A long-running theme here at SV-POW!
A lesson we don’t want to learn
Authors: Taylor Mike
Published: November 2023

Matt just wrote this, in an email exchange.  It struck a chord in me, and I thought it deserved a wider audience: Rats. Cervical vertebra V (from an unknown position in the anterior part of the neck) of the STILL undescribed Tendaguru brachiosaurid NHM R5937, "The Archbishop", in right lateral view. The posterior portion is missing in action.
Tutorial 16: giving good talks, part 4: delivery
Authors: Taylor Mike
Published: November 2023

And so we come, rather belatedly, to the fourth and final part of this series on preparing and giving talks at scientific conferences.  If you’ve followed the previous installments, you should have figured out a clear, compelling story that you want to tell from your research; you should have clear slides with striking, relevant images and no visual distractions;
Can you identify these five sauropod cervicals?
Authors: Taylor Mike
Published: November 2023

Sorry to have written so much about publishing politics recently, and so little about sauropod vertebrae!  That stuff is important, and I give you fair warning I will be returning to it soon.
Authors versus publishers
Authors: Wedel Matt
Published: November 2023

You don’t need to read this. You can read Scott Aaronson’s Review of  The Access Principle  and Tim O’Reilly’s Piracy is Progressive Taxation and connect the blindingly obvious dots. OTOH, Aaronson and O’Reilly wrote their pieces for the same reason I’m writing this one: some things are not blinding obvious to everyone. And sometimes the situation makes me mad enough to take a swing. So here goes.
Skulls … Ah, they’re not all bad
Authors: Taylor Mike
Published: November 2023

Every now and then, you come across a sauropod skull so beautiful, it’s almost enough to distract you from the vertebrae that it was attached to.  One such is the  Giraffatitan brancai  skull HMN T1, which you’ve seen here before if you’ve been around for a while.
Notifications: Prizes past and future, sauropods on Jurassic CSI
Authors: Wedel Matt
Published: November 2023

It’s been a little quiet around here lately. Mike has been slammed with day-job work, Darren is terminally busy as always, and I’m in my fall teaching block so I’ve been too busy to think. But life rolls on and there are announcements that need making. To wit: – My post on the long nerves of sauropods was chosen as one of ten blog posts for the Science Writer Tip Jar at Not Exactly Rocket Science, back in May.
Blog citations are better than pers. comms.
Authors: Wedel Matt
Published: November 2023

Here’s an excerpt from a Google chat conversation that Mike and I had last May. I’m posting it now as a break from the OA Wars, and because it’s annoying to have to keep track of stuff that we know about but haven’t talked about publicly.  Matt:  Something occurred to me the other day, and I can’t remember whether I’ve discussed it with you or not. So sorry in advance if it’s a dupe.  Mike:  np.
Brontomerus in magazines: preparing for the media
Authors: Taylor Mike
Published: November 2023

With our baby’s appearance in  National Geographic  this week, she’s now been in four mainstream magazines: That’s  National Geographic  at top left,  Macleans  next to it;  The Scientist  at bottom left, and  National Geographic Kids  next to that.
On a lighter note…
Authors: Wedel Matt
Published: November 2023

Something about this photo from the last post has been bugging me all week. It’s the expression on my face. The set jaw, the thrust forward chin, the cocked eyebrow…I knew I had seen these things before. It took me a while, but I was finally able to place it. My doppelganger: If this is an omen, I have no idea what it means. Science will resume shortly.
Brontomerus in National Geographic
Authors: Wedel Matt
Published: November 2023

Brontomerus by Mauricio Antόn, copyright National Geographic The October 2011 issue of  National Geographic  is out, and in the ‘Now’ section near the front there is a one-page feature on  Brontomerus  (in the US version anyway).  The whole thing is can be viewed online here.  It’s page 30 in the hardcopy, but  NG  seems pretty cavalier about printing page numbers.
The Elephant in the Cave: Accurate vs Familiar vs Usual in Paleoart
Authors: Wedel Matt
Published: November 2023

Photo copyright Derek Bromhall, borrowed from ARKive. Let’s say you want to paint an elephant. Where will you locate your elephant, and what will it be doing? If you depict an elephant standing on a glacier at 14,000 feet, your depiction is accurate, because elephants have been caught doing that. Elephant, standing in a dunescape with no water or vegation in sight: accurate, for the same reason.
Vulvar sarcoma in a young patient with neurofibromatosis syndrome with missed opportunities: A case report
Authors: Kihagi Consolata , Cheserem Eunice , Kamau John , Ndayisaba Dorel , Mokomba Alfred , Kosgei Rose
Published: November 2023

Background: Vulvar malignancies are the fourth commonest of genital malignancies. The sarcoma type is associated with neurofibromatosis disease.

Case presentation: A 29-year-old nulliparous presented to the outpatient gynecological clinic with a five-year history of a recurrent right vulvar mass. The mass was initially excised without histological analysis. Histological examination of a reexcised mass diagnosed a spindle cell sarcoma. She was then lost to follow-up for one year. The mass recurred and she received external beam radiation. On admission, she was in good general status with generalized café-au-lait spots and neurofibromas. Perineal examination revealed an ulcerated right vulvar mass. Toilet vulvectomy and diversion colostomy were performed followed by chemotherapy. She was discharged after five months with a well-granulated wound. Colostomy was reversed six months later.

Conclusion: Vulvar sarcoma is a rare vulvar malignancy type usually associated with neurofibromatosis. This case highlights the missed opportunities in its management. A high suspicion threshold is critical for early diagnosis and management to curb the morbidity and mortality rate.
El matrimonio como amistad
Authors: Adame Goddard Jorge
Published: November 2023

El matrimonio es amistad, es decir amor recíproco y pleno entre varón y mujer. Los novios tienen una clara y dichosa experiencia de lo que es su amistad, y por ella pueden disponerse a comprometerse, a asumir públicamente, ante la sociedad civil y la sociedad religiosa, que mantendrán su amistad durante toda su vida, pase lo que pase. Si no han soñado con amar para siempre es que no han tenido una plena amistad matrimonial, y se conforman con algo menos valioso, la amistad meramente útil. La amistad plena con visión de futuro es la esencia del noviazgo. Quienes quieren progresar en ella hacen un compromiso, se casan públicamente. El compromiso matrimonial fortalece la amistad de los novios para que dure toda su vida. Hecho el compromiso, el matrimonio sigue siendo amistad de dos que se procuran recíprocamente, con todas sus fuerzas, ayudarse para alcanzar la felicidad temporal y eterna y para recibir y educar en la amistad a los hijos que lleguen a procrear. Este trabajo explica lo que es la amistad honesta, y cómo prepara, conserva y fortalece el matrimonio.
El verdadero secreto de la evolución. Del conflicto a la colaboración.
Authors: Valerio Bellieni Carlo , Velazquez Lourdes
Published: November 2023

El evolucionismo sigue evolucionando. Este libro cuenta con un lenguaje claro y muchos ejemplos, como lo que sabemos del cambio de vida en la tierra sigue siendo poco. Pero lo poco que sabemos debe hacernos humildes al no sacar conclusiones radicales, sino también abiertas a las novedades encontradas por la ciencia. Y la mayor novedad es que la colaboración entre las especies tiene un peso al menos igual que la lucha entre ellas, para explicar la evolución de la vida. El neodarwinismo, que vino ideológicamente después de las ideas claras de Darwin, quiere pensar que prevalece lo más adecuado, y en esto parece querer justificar varias formas de supremacía y colonialismo. Inconscientemente, esto está representado por el clásico símbolo iconográfico en el que se ve el mono y del mono nace el mono màs grande, y del mono màs grande el Nehanderthal, y al fin el hombre ... pero siempre es y solo blanco y varòn; casi para representar con estas características el sumo nivel de evolución. En cambio, hoy descubrimos que las especies hablan y se confunden entre sí; que el árbol de la vida tiene ramas que se separan, y que se fusionan, se enredan y se separan nuevamente; que el entorno afecta cómo habla el ADN. Y sabemos que el secreto de la vida es la colaboración y la solidaridad. Dos académicos, un médico y una filosofa, ambos bioéticos de renombre, explican aquí en detalle este proceso. Es un libro que debería llevarse a las escuelas y a las universidades para reabrir un debate que la costumbre y la pereza han mantenido firme durante décadas.
En busca del cuerpo personal. Más allá de la naturaleza y la subjetividad
Authors: Armida Diego , I. Vargas Alberto
Published: November 2023

"Hoy vivimos el reino de los iguales en el que el sí mismo gobierna para sí mismo y la relación se presenta como una extrajera indeseable. Es por esto que la diferencia mujer-varón se ha vuelto prohibida y la profundización en la complementariedad y dualidad de los sexos queda censurada en los espacios públicos e inexplorada en los campos del saber. Sin referente para fundar los datos científicos al respecto, en el mundo de los iguales no se encuentran alternativas para resolver esta crisis identitaria abandonando al hombre contemporáneo a la perplejidad ante la propia vida y las de los demás. Cada época tiene un tema al que enfrentarse y posiblemente el de nuestra época sea el asunto del propio cuerpo. Tanto en el ámbitos de la vida cotidiana como en el de las ciencias, el tema del cuerpo se presenta especialmente efervescente y esquivo en orden a encontrar respuestas sobre las cuales fundar la organización de la vida pública y privada. En esta investigación se ofrece una panorámica de las tres grandes comprensiones antropológicas sobre la corporalidad humana: la clásica griega, la cristiana y la moderna contemporánea. Los autores pretenden detectar las ventajas y limitaciones de los diversos planteamientos de los grandes pensadores de la historia en búsqueda de una articulación integral que por un lado, dé respuesta al enigma del propio cuerpo y a su sentido más trascendente y que, además, abra la esperanza de encontrar manifiesta en él la novedad de cada quién. Estamos pues ante una panorámica introductoria a este apasionante tema en orden a servir de plataforma para futuras investigaciones."
Socialismo democrático e de mercado
Authors: Rodrigues Castilho Sergio Ricardo
Published: November 2023

A crise da esquerda diz respeito, entre outras coisas, a sua incapacidade tanto de compreender historicamente a resiliência do capitalismo quanto de estabelecer um programa de ação que seja capaz de mobilizar amplas massas na resistência e construção de alternativas. O artigo pretende apresentar alguns marcos teóricos iniciais que possam servir para a construção de alternativas programáticas. Esses marcos programáticos estão relacionados às questões relativas ao tipo de corpo político (a democracia socialista) e às fundações econômicas e sociais (o socialismo de mercado) que pretendemos construir. Para tal, faremos uma revisão crítica sintética do legado marxiano e marxista. Em seguida, revisitaremos a questão da democracia, procurando reconstruir uma concepção que integre socialismo e democracia, dialogando não apenas com o marxismo, mas também com o liberalismo. Por último, trataremos da questão das fundações socioeconômicas da sociedade pós-capitalista, argumentando que uma concepção equivocada do que seja "mercado" acaba por solapar qualquer possibilidade real de superação do capitalismo. Nas conclusões trataremos da articulação entre as dimensões econômicas e políticas na luta pelo socialismo e apresentaremos algumas ideias para a reforma do Poder Legislativo.
O desafio da esquerda ante o Brasil pós-católico
Authors: Arenari Brand
Published: November 2023

Este artigo de tom ensaístico trata da possibilidade de a esquerda se adaptar ou não ao novo ambiente (ecossistema político) de um Brasil pós-católico. Descreveremos o novo meio ambiente (Brasil pós-católico) gerado pela chegada de uma nova espécie/tipo social “invasor” (neopentecostais), para em seguida analisar os impactos e reações do campo da esquerda a esses novos desafios, especialmente sua principal força eleitoral, o Partido dos Trabalhadores. No que se refere ao Partido dos Trabalhadores, destacaremos e descreveremos dois elementos constitutivos de sua formação e desenvolvimento que, segundo nossa análise, se apresentam como impedimentos iniciais (não determinísticos) a sua adaptação à nova ordem pós-católica: (1) o papel do catolicismo e (2) a intelectualidade acadêmica na sua formação e desenvolvimento.
A crise da esquerda e sua superação
Authors: Sávio Teixeira Carlos , Dutra Roberto
Published: November 2023

A esquerda experimenta hoje estagnação intelectual e política. Tem sido incapaz de apresentar alternativas críveis de reorganização das estruturas da vida social que tanto critica. E, mesmo rebaixando suas expectativas a ponto de muitas vezes quase não se distinguir programaticamente do centro – e até da direita –, vê-se com dificuldades eleitorais e assiste, atônita, em muitos lugares, a seus adversários “populistas de extrema direita” ascenderem ao poder com apoio de parte significativa de classes e grupos sociais cujos interesses e ideias a esquerda sempre pretendeu representar. Os limites do redistributivismo das políticas de ganhos marginais e da lógica da compensação parecem ter ficado patentes, pelo menos para a maioria das pessoas comuns. A falta de alternativas estruturais e institucionais parece se alimentar do encurtamento dos horizontes teóricos e práticos sobre o que é possível em termos de transformação e reorganização da vida social em suas diferentes esferas. É como se o futuro e o novo tivessem deixado de ser aliados para serem adversários.
Basal Cell Skin Cancer, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology
Authors: Schmults Chrysalyne D. , Blitzblau Rachel , Aasi Sumaira Z. , Alam Murad , Amini Arya , Bibee Kristin , Bordeaux Jeremy , Chen Pei-Ling , Contreras Carlo M. , DiMaio Dominick , Donigan Jessica M. , Farma Jeffrey M. , Ghosh Karthik , Harms Kelly , Ho Alan L. , Lukens John Nicholas , Mark Lawrence , Medina Theresa , Nehal Kishwer S. , Nghiem Paul , Olino Kelly , Park Soo , Patel Tejesh , Puzanov Igor , Rich Jason , Sekulic Aleksandar , Shaha Ashok R. , Srivastava Divya , Thomas Valencia , Tomblinson Courtney , Venkat Puja , Xu Yaohui Gloria , Yu Siegrid , Yusuf Mehran , McCullough Beth , Espinosa Sara
Published: November 2023

Basal cell carcinoma (BCC) is the most common form of skin cancer in the United States. Due to the high frequency, BCC occurrences are not typically recorded, and annual rates of incidence can only be estimated. Current estimated rates are 2 million Americans affected annually, and this continues to rise. Exposure to radiation, from either sunlight or previous medical therapy, is a key player in BCC development. BCC is not as aggressive as other skin cancers because it is less likely to metastasize. However, surgery and radiation are prevalent treatment options, therefore disfigurement and limitation of function are significant considerations. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) outline an updated risk stratification and treatment options available for BCC.
Association Between Pretreatment Chest Imaging and Immune Checkpoint Inhibitor Pneumonitis Among Patients With Lung Cancer
Authors: Wong Alexander , Riley Maria , Zhao Songzhu , Zimmer Jessica , Viveiros Matthew , Wang Jing Gennie , Esguerra Vincent , Li Mingjia , Lopez Gabrielle , Kendra Kari , Carbone David P. , He Kai , Alahmadi Asrar , Kaufman Jacob , Memmott Regan M. , Shields Peter G. , Brownstein Jeremy , Haglund Karl , Welliver Meng , Otterson Gregory A. , Presley Carolyn J. , Wei Lai , Owen Dwight H. , Ho Kevin
Published: November 2023

Background: Immune checkpoint inhibitors (ICIs) are a first-line and perioperative treatment for lung cancer. Pneumonitis is a potentially life-threatening complication of ICI treatment in 2% to 5% of patients; however, risk factors for developing ICI pneumonitis (ICI-p) remain undefined. Methods: We conducted a retrospective cohort study of consecutive patients with lung cancer who received at least one dose of ICI from 2015 through 2020 at The Ohio State University. Pneumonitis cases were documented by the treating oncologist and retrospectively evaluated for agreement between an oncologist and a pulmonologist. Patient demographic and clinical characteristics were recorded and summarized between those with and without pneumonitis for the overall cohort. Univariate and multivariable survival analyses using the Fine-Gray competing risk model were used to examine the associations. Results: A total of 471 patients with lung cancer were included, of which 402 had non–small cell lung cancer and 69 had small cell lung cancer; 39 (8%) patients in the overall cohort developed ICI-p. Preexisting interstitial abnormalities and prior chest radiation were both significantly associated with ICI-p on univariate analysis (hazard ratio [HR], 8.91; 95% CI, 4.69–16.92; P<.001; and HR, 2.81; 95% CI, 1.50–5.28; P=.001). On multivariable analyses, interstitial abnormalities remained a strong independent risk factor for ICI-p when controlling for chest radiation and type of immunotherapy (HR, 9.77; 95% CI, 5.17–18.46; P<.001). Among patients with ICI-p (n=39), those with severe (grade 3–5) pneumonitis had worse overall survival compared with those with mild (grade 1 or 2) pneumonitis (P=.001). Abnormal pulmonary function test results at both 12 and 18 months prior to ICI initiation were not significantly associated with ICI-p. Conclusions: Preexisting interstitial abnormalities on chest CT and prior chest radiation are independent risk factors that are strongly associated with ICI-p in patients with lung cancer. These findings highlight a potential need for closer observation for ICI-p among patients with these risk factors.
Smoking Cessation and Pancreatic Cancer Risk in Individuals With Prediabetes and Diabetes: A Nationwide Cohort Study
Authors: Park Joo-Hyun , Hong Jung Yong , Shen Jay J. , Han Kyungdo , Park Young Suk , Park Joon Oh
Published: November 2023

Background: Individuals with diabetes and prediabetes are at increased risk of pancreatic cancer. However, little is known about the effects of smoking or smoking cessation on pancreatic cancer risk in individuals with diabetes and prediabetes. We investigated the association between smoking status (particularly smoking cessation) and pancreatic cancer risk according to glycemic status. Patients and Methods: This nationwide cohort study included 9,520,629 adults without cancer who underwent the Korean National Health Screening in 2009 and were followed until 2018. Hazard ratios and 95% confidence intervals for pancreatic cancer were estimated after adjusting for potential confounders. Results: During the 78.4 million person-years of follow-up, 15,245 patients were newly diagnosed with pancreatic cancer. Among individuals with diabetes and prediabetes, current smoking synergistically increased pancreatic cancer risk (all P<.01). However, quitters with diabetes and prediabetes had a pancreatic cancer risk comparable to that of never-smokers (all P>.05). For pancreatic cancer in current smokers, quitters, and never-smokers, respectively, the hazard ratios were 1.48 (95% CI, 1.40–1.58), 1.11 (95% CI, 1.03–1.19), and 1.00 (reference) among individuals with normoglycemia; 1.83 (95% CI, 1.70–1.97), 1.28 (95% CI, 1.18–1.39), and 1.20 (95% CI, 1.14–1.26) among individuals with prediabetes; and 2.72 (95% CI, 2.52–2.94), 1.78 (95% CI, 1.63–1.95), and 1.63 (95% CI, 1.54–1.72) among individuals with diabetes. There were no differences in risk between quitters with a <20 pack-year smoking history and never-smokers in all glycemic status groups. Conclusions: Pancreatic cancer risk synergistically increased in current smokers with diabetes and prediabetes. However, smoking cessation reduced the synergistically increased risk of pancreatic cancer to the level of never-smokers, especially when smoking history was <20 pack-years. More individualized and intensive cancer prevention education should be underscored for individuals at an increased risk of pancreatic cancer beyond the one-size-fits-all approach.
Protocolo de autocuidado para pacientes con psoriasis desde la farmacia comunitaria
Authors: Paradas Palomo Teresa , Valverde Merino Maria Isabel , Martinez Martinez Fernando , Zarzuelo Romero Maria Jose
Published: November 2023

Introducción: Debido a la baja calidad de vida y adherencia al tratamiento de los pacientes con psoriasis se plantea desarrollar un protocolo de empoderamiento que conduzca a un mayor conocimiento del autocuidado en pacientes con esta patología, acorde a sus necesidades, siendo importante el papel del farmacéutico para la mejora de ambos. 
Método: Se administró el test Morisky Green-4 items y el cuestionario Dermatology Life Quality Index a 40 pacientes con psoriasis que acudían a una farmacia comunitaria. Con estos datos, la información de las guías clínicas y la colaboración con un dermatólogo, se diseñó un protocolo de autocuidado.
Resultados: Se observó falta de adherencia en el 100% de los pacientes y una calidad de vida leve/moderada (5,3±4,2), en las preguntas relacionadas con: los síntomas cutáneos afectan mucho/muy al 50% de los pacientes y la sensación de vergüenza y dificultad con su tratamiento entre poco y mucho en el 60%. Con estos resultados se diseñaron dos dípticos. A los 3 meses la calidad de vida mejoró a 3,98±2,05, p=0,048, y se observó falta de adherencia en el 70% de los pacientes.
Conclusiones: Los protocolos de autocuidado son necesarios para mejorar la calidad de vida de los pacientes crónicos. El papel del farmacéutico es importante a través de un protocolo de autocuidado en pacientes con psoriasis, ayudando a mejorar la adherencia al tratamiento y la calidad de vida.
PELAKSANAAN 5R DI BENGKEL TKR SMK NEGERI 2 LINGSAR DALAM MEWUJUDKAN SEKOLAH BERBASIS INDUSTRI
Authors: SUWARDI SUWARDI
Published: November 2023

Tujuan penelitian ini adalah untuk mendeskripsikan implementasi ringkas, rapi, resik, rawat, rajin (5R) di bengkel teknologi kendaraan ringan SMK Negeri 2 Lingsar, meliputi (1) perencanaan implementasi 5R dalam pengelolaan bengkel, 2) implementasi 5R dalam pengelolaan bengkel, (3) Pengawasan pelaksanaan 5R dalam pengelolaan bengkel. Penelitian ini menggunakan metode penelitian deskriptif kualitatif. Subyek penelitian ini adalah kepala sekolah, ketua jurusan, teknisi, guru dan siswa kelas jurusan teknologi kendaraan ringan SMK Negeri 2 Lingsar. Pengumpulan data dalam penelitian ini melalui observasi, wawancara dan dokumen. Dari hasil penelitian disimpulkan bahwa (1) perencanaan penerapan sikap kerja 5S dalam pengelolaan bengkel dilaksanakan dengan baik. Kepala sekolah, ketua jurusan dan teknisi terlibat dalam perencanaan implementasi 5S. Perencanaan implementasi 5R meliputi perencanaan 5R, pembentukan PIC dan perencanaan kegiatan untuk mendukung implementasi 5R, (2) pelaksanaan manajemen bengkel yang ringkas, rapi, resik, rawat dan rajin berjalan baik (3) Pengawasan implementasi 5R melibatkan ketua jurusan, teknisi dan guru. Pengawasan yang dilakukan dalam pengelolaan bengkel berupa pemeliharaan alat dan bahan praktik serta pengisian control checklist, (4) ) hambatan dalam pelaksanaannya penyediaan perangkat pendukung yang belum maksimal. Cara mengatasi dengan melakukan sosialisasi 5R secara berkala, membentuk tim manajemen yang solid, dan memelihara alat dan bahan praktik secara berkala.
Optimasi Akses Informasi Sekolah Negeri Pao-Pao melalui Pengembangan Website Interaktif
Authors: Fadhil Irlan  , Mappangara Surianto
Published: November 2023

At SDN Pao-Pao Makassar the process of conveying and obtaining information is carried out in the same way as usual, namely by waiting and having to come directly to school. To solve this problem, the author has a desire to make it easier for teachers, students or parents/guardians of students to know and convey school information. So the solution to this problem is to build a school information system website that can be accessed via the internet. The existence of this website can make it easier for teachers, students and parents/guardians of students to find school information quickly and practically. The mechanism of this information system is that the administrator manages and regulates the course of the school information system, the teacher manages the learning outcomes of students, while students or parents/guardians of students can see the results of student learning activities. Meanwhile, visitors can only see information about the school. The analysis and design tools used in the development of this website are system development methodologies, namely Use Case Diagrams. The information provided by SDN Pao-Pao using the internet is expected to make it easier for the general public to obtain up to date information.
Sosialisasi Literasi Keuangan Pada Generasi Muda
Authors: Aslam Annisa Paramaswary , Aswar Nurul Fadilah , Mustafa Muhammad Yushar , Abadi Rahmat Riwayat , Pratiwi Andi Citra
Published: November 2023

Literasi keuangan mempunyai peran penting dalam mendukung pembangunan keuangan di suatu negara terutama pada negara berkembang seperti Indonesia. Pelaksanaan sosialisasi materi literasi keuangan dilakukan dengan materi seperti pengertian dan tujuan dari literasi keuangan, bagaimana merencanakan keuangan, mengatur pengeluaran dan pendapatan serta contoh instrument investasi keuangan di masyarakat. Kegiatan pengabdian ini dilakukan pada tanggal 28 Mei 2023 dan dilakukan secara daring melalui aplikasi zoom. Pengabdian ini dihadiri oleh 42 peserta yang hadir dalam zoom ini, dimana latar belakang peserta terdiri dari mahasiswa, karyawan swasta, guru, dokter, dan lain-lain yang berasal dari 3 kota di Indonesia yaitu Jakarta, Makassar, dan Surabaya. Tujuan ini pengabdian ini  untuk mendukung kebijakan pemerintah mengenai peningkatan literasi inklusi keuangan termasuk meningkatkan pemahaman masyarakat tentang keuangan pribadi, termasuk pengelolaan hutang, perencanaan keuangan, dan investasi.