bluuebunny/crossref_metadata_2025 huggingface dataset:
Cold War Contexts: Pawlikowski in Film, Television, and European History
Authors: White Jerry
Published: February 2019

Jerry White compares Paweł Pawlikowski's new film Zimna wojna (Cold War, 2018) to Karpo Godina's classic Slovenian film Rdeči boogie ali Kaj ti je deklica (Red Boogie, 1982), discussing the narrative and thematic continuities between the two films in the context of Cold War history and cinema. White also explores Pawlikowski's prior incarnation as a British documentary filmmaker named Paul to suggest a curious evolution; that in returning to his native Poland in his most recent films (Cold War and Ida), Pawlikowski has gone astray, abandoning the authenticity of his early British films such as Last Resort for a muddled romantic vision.
Bilateral Internal Thoracic Artery Grafting in Women: A Word of Caution
Authors: Schoell Thibaut , Genser Laurent , Clément Marina , Amour Julien , Leprince Pascal , Lebreton Guillaume , Tavakoli Reza
Published: February 2019

Background: Despite the superior hemodynamic performance of internal thoracic arteries, total arterial revascularization with exclusive bilateral internal thoracic arteries (BITA) is less frequently used especially in specific subsets of patients, including females. We report our experience with total arterial revascularization with exclusive BITA regardless of sex and analyze the impact of female sex on the early and midterm outcomes.
Methods: Total arterial revascularization with exclusive BITA was performed with equal frequency in females (79/99, 80%) and males (392/477, 82%; P = .68) undergoing isolated CABG for 3-vessel disease. Pre, intra and postoperative data were compared between these two groups.
Results: Complete revascularization was achieved in 77% of females and 72% of males (P = .08). Early mortality did not differ between the groups (6.3% versus 4.6%, P = .7). The incidence of re-sternotomy for bleeding, postoperative stroke, myocardial infarction, new onset atrial fibrillation, and hemofiltration for renal failure did not differ between the two groups. However, there were significantly more wound revision for combined superficial and deep sternal wound infection in females (26.5% versus 5.1%, P = .0001). Nevertheless, midterm survival, freedom from repeat revascularization, myocardial infarction, stroke, and major adverse cardiovascular and cerebral events at five years were very good and compared favorably between females and males.
Conclusions: Our findings suggest that total arterial myocardial revascularization with exclusive internal thoracic arteries in females carries the same midterm benefits as in males. Early outcomes are comparable except for a higher incidence of wound revision for combined superficial and deep sternal wound infections in females compared to males. Benefits of bilateral internal thoracic artery grafting in females should be weighed against increased risk of early wound revision.
You Are the Perfect Age: An Inquiry into Surgical Ethics during the Arc of a Career
Authors: Tribble Curt G
Published: February 2019

There is an old saying that history only makes sense in retrospect. I am sure that I am as susceptible to this adage as any other person. However, I will tell the story of my long history as an amateur medical ethicist, which is, to this day, how I would describe myself. My interest in the ethics of medicine, particularly as these ethical principles apply to interventions or procedures, started at a young age, fairly frequently going to the hospital with my father, a General and Thoracic Surgeon. I think that I found myself agreeing to accompany him, when invited, presuming that doing so would be a chance to spend some time with my dad, who was, throughout my childhood, either a surgical resident or a busy practicing surgeon. I will admit that I probably also figured that, at least late at night on the way home, we would stop by some establishment where we could get burgers and fries.
However, I will start my reminiscences and reflections on these issues with a more recent story, as it prompted me to think back on my perceptions of those experiences of my youth.
Geoprocessamento aplicado a análise geoambiental no Município De Vitória da Conquista-Bahia
Authors: Andrade Martínez Everardo , De Niz-Lara, Ingeniera Emma María , Benítez-Muñoz Miguel Ángel , Olguín-López José Luis , Guevara-Gutiérrez Rubén Darío , Meza-Rodriguez Demetrio , Villalvazo-López Víctor Manuel
Published: February 2019

En la actualidad existe escasa investigación sobre la identificación de áreas aptas para implementar la actividad agrícola de temporal utilizando los cultivos de maíz y frijol en la cuenca de Autlán. Para delimitar superficies idóneas en la zona de estudio, se empleó la metodología multicriterio (Proceso Analítico Jerárquico) y los Sistemas de Información Geográfica utilizando como fuente principal la información procedente de las encuestas semi-estructuradas. Los parámetros obtenidos reúnen las condiciones ideales de suelo y clima para el desarrollo del maíz y frijol en superficies con actividad agrícola de temporal; identificando áreas aptas en el 38.08% de la superficie total de la cuenca. Para el 14.23% se sugiere implementar una agricultura efectuando prácticas de conservación de suelo y agua tomando en cuenta la existencia en el incremento de la pendiente del terreno y presencia de suelos poco profundos, estas características pueden aumentar el riesgo de erosión. El área restante debe ser identificada como zona de protección por distribuirse en zonas de montaña.
Análisis multiespectral para la estimación de la turbidez como indicador de la calidad del agua en embalses del estado de Chihuahua, México
Authors: Amado-Alvarez Jesús , Pérez-Cutillas Pedro , Alatorre-Cejudo Luis Carlos , Olguín-López José Luis , Ramírez-Valle Orlando , Segovia-Ortega Elsa Fabiola , Alarcón-Cabañero Juan José
Published: February 2019

La cuenca del río Conchos, situada en el Estado de Chihuahua (México), ha sufrido un notable deterioro por el desarrollo de las actividades humanas. El crecimiento urbano, la industrialización y la agricultura han degradado de manera notable los recursos hídricos de esta cuenca. Para examinar la calidad de sus aguas se han analizado los embalses de la presa de Las Vírgenes, el lago Colina y la presa la Boquilla, determinando los parámetros de Oxígeno Disuelto, pH, Nitratos, Sólidos Totales Disueltos, Turbidez y Temperatura a partir de muestras de agua. Mediante estos datos y la información espectral de imágenes del satélite Landsat 5 se evaluaron 30 modelos de regresión lineal de los cuales, la turbidez obtuvo el mejor ajuste. Las regiones del espectro 0,52 – 0,6 μm y 0,63 - 0,69 μm, aportados por la variable predictora, se mostraron como los rangos de mayor correlación con los valores de turbidez. El modelo empleado para representar la turbidez espacialmente distribuida muestra que la presa la Boquilla obtiene los valores más altos, relacionados con la suspensión de sedimentos aportados por cauces efímeros a lo largo de todo el embalse.
Fisonomía y diversidad del bosque secundario de Prosopis caldenia. Provincia de la Pampa, Argentina
Authors: S. Duval Valeria , M. Benedetti Graciela , M. Campo Alicia
Published: February 2019

El bosque de caldén (Prosopis caldenia) es una formación vegetal endémica de la Argentina distribuido, principalmente, en la provincia de La Pampa. El valor económico de la madera del caldén fue una de las causas por las que este bosque esta actualmente degradado y fragmentado. Es por ello, que la existencia de áreas protegidas que preserven esta masa forestal es fundamental para su conservación. El objetivo del trabajo fue analizar la fisonomía y diversidad de la vegetación en el bosque de caldén en la Reserva Provincial Parque Luro, provincia de La Pampa, Argentina. Para ello, se aplicaron metodologías de relevamiento de vegetación, índices de diversidad, valor de importancia y NDVI. Los resultados mostraron un cambio de fisonomía en relación con el bosque prístino. Se reconoce que el estrato arbustivo adquirió mayor cobertura, aunque el caldén continúa siendo la especie con mayor valor de importancia en el bosque.
Descompresión medular mediante abordaje lateral transtorácico mínimamente invasivo. Reporte de un caso. [Spinal cord decompression by minimally invasive transthoracic lateral approach. Case report]
Authors: Martínez Augusto Esteban , Lanari Subiaur Felipe Jose , Mounier Carlos María , Prina José Ricardo , Gutiérrez Ramiro , Gobbi Enrique Augusto
Published: February 2019

Existen múltiples técnicas para la descompresión medular en la columna torácica, cada una con sus ventajas y desventajas y con distintos requerimientos de destrezas quirúrgicas. Se han desarrollado técnicas mínimamente invasivas que disminuyen las tasas de morbilidad, con buenos resultados funcionales. Se presenta el caso de un hombre de 64 años, con clínica de compresión medular, una hernia de disco central, calcificada a nivel del quinto disco torácico, migrada hasta el borde inferior de la sexta vértebra torácica, con franca compresión medular. Se realizó un abordaje lateral transpleural mínimamente invasivo, con una corpectomía parcial posterior de la sexta vértebra, sin fijación adicional. El paciente tuvo una buena evolución, sin progresión del cuadro neurológico ni dolor costal residual.Los abordajes laterales mínimamente invasivos son técnicas válidas para tratar patologías compresivas de la columna torácica, con bajas tasas de morbimortalidad y una rápida recuperación. AbstractThere are multiple techniques for spinal cord decompression in the thoracic spine, each with its advantages and disadvantages, and requiring different surgical skills. Recently, minimally invasive techniques have been developed, reducing morbidity rates and achieving good functional results.We present the case of a 64-year-old male with spinal compression symptoms, central disc herniation calcified at the fifth thoracic vertebra, which migrated to the lower end of the sixth thoracic vertebra. Diagnosis was clear for spinal cord compression. Partial posterior corpectomy of the sixth vertebra was performed with a minimally invasive transthoracic transpleural lateral approach and without additional fixation. The patient had a good outcome on follow-up, without progression of neurological symptoms or residual rib pain.Minimally invasive lateral approaches are valid techniques for the treatment of compression disorders of the thoracic spine, with low rates of morbidity and mortality, and a rapid recovery.
Giant Congenital Melanocytic Nevus Treated With Trametinib
Authors: Mir Adnan , Agim Nnenna G. , Kane Alex A. , Josephs Shellie C. , Park Jason Y. , Ludwig Kathleen
Published: February 2019

Giant congenital nevi are melanocytic proliferations of the skin that may be complicated by melanoma, neurocutaneous melanocytosis, pain, pruritus, and disfigurement. Current treatment options include surgical resection and medical management of associated symptoms. There is limited efficacy in these modalities. No effective pharmacologic treatments are available for the treatment of these lesions. We present the case of a 7-year-old girl with a giant congenital melanocytic nevus that had an AKAP9-BRAF fusion and was treated with trametinib, which resulted in rapid resolution of the patient’s lifelong, intractable pain and pruritus as well as dramatic improvement in the extent of her nevus.
Subclinical Left Ventricular Dysfunction During Chemotherapy
Authors: Nicol Martin , Baudet Mathilde , Cohen-Solal Alain
Published: February 2019

Subclinical left ventricular dysfunction is the most common cardiac complication after chemotherapy administration. Detection and early treatment are major issues for better cardiac outcomes in this cancer population. The most common definition of cardiotoxicity is a 10-percentage point decrease of left ventricular ejection fraction (LVEF) to a value <53%. The myocardial injury induced by chemotherapies is probably a continuum starting with cardiac biomarkers increase before the occurence of a structural myocardial deformation leading to a LVEF decline. An individualised risk profile (depending on age, cardiovascular risk factors, type of chemotherapy, baseline troponin, baseline global longitudinal strain and baseline LVEF) has to be determined before starting chemotherapy to consider cardioprotective treatment. To date, there is no proof of a systematic cardioprotective treatment (angiotensin-converting enzyme inhibitor and/or betablocker) in all cancer patients. However, early cardioprotective treatment in case of subclinical left ventricular dysfunction seems to be promising in the prevention of cardiac events.
Biomarkers in Routine Heart Failure Clinical Care
Authors: Nadar Sunil K , Shaikh Muhammad Mujtaba
Published: February 2019

Heart failure is a clinical condition with complex pathophysiology that involves many different processes. Diagnosis is often difficult in patients presenting for the first time with breathlessness. Many biomarkers have been identified that are elevated in heart failure and their role in assessing prognosis has also been investigated. However, at present the natriuretic peptides appear to be the gold standard biomarker against which the other biomarkers are compared. In this review we will examine the evidence behind the other biomarkers for use in heart failure patients and the current guidelines for their use.
Exercise Training and Heart Failure: A Review of the Literature
Authors: Morris Jacqueline H , Chen Leway
Published: February 2019

Exercise and cardiac rehabilitation have been underused therapy options for patients with congestive heart failure despite being recommended in international guidelines and being covered by Medicare in the US. This article reviews the evidence behind this treatment strategy and details current trials that will contribute to the evidence base.
Construyendo mejores sociedades: los grupos escolares y el proceso de inclusión-exclusión educativa
Authors: Batista Sardain Patricia , Torralbas Oslé Jorge Enrique
Published: February 2019

La escuela tiene el reto de ser el espacio donde se decide el rumbo de nuestras sociedades. En el empeño de sociedades más justas e inclusivas es preciso comprender el entramado socioeducativo y su impacto de forma más compleja, especialmente el grupo escolar como espacio de mediación. Para ello se propone, como alternativa teórica para el análisis de los procesos de inclusión-exclusión educativa, un marco conceptual que comprende las desigualdades desde la subjetividad social/grupal y coloca la mirada sobre la responsabilidad institucional. En este ensayo discutiremos sobre la responsabilidad de las instituciones escolares en las garantías para la inclusión, el papel del personal docente en el diseño de la actividad escolar y el funcionamiento de los grupos escolares desde su relación con el proceso de inclusión-exclusión educativa. Se presentan algunas características para entender la articulación de estas dimensiones y la forma en que cada una de ellas favorece o dificulta la inclusión. De este modo, se muestra que, junto a los elementos estructurales y políticas educativas, la subjetivación del proceso en la vida cotidiana de la escuela garantiza mayores o menores niveles de inclusión. El ensayo defiende la noción de grupo para trabajar con una perspectiva más social de la educación y sus ventajas en el proceso de formación. Muestra cómo, en el proceso de inclusión-exclusión educativa, influyen de forma articulada las decisiones y las estrategias institucionales que organizan y estructuran la vida de los grupos escolares, sentando las pautas para la experiencia escolar.
Investigación en la Universidad de Holguín: compromiso con la Agenda 2030 para el desarrollo sostenible.
Authors: León Pupo Neysi Ileana , Castellanos Domínguez María Isabel , Curra Sosa Dagnier , Cruz Ramírez Miguel , Rodríguez Palma Maura Isabel
Published: February 2019

Las universidades son agentes de cambio buscando espacios en los que fomentar la investigación interdisciplinar para lograr estilos de vida sostenibles encaminados al cumplimiento de los Objetivos de Desarrollo Sostenible (ODS) de la Agenda 2030. En este artículo se realiza un estudio de la contribución de la Universidad de Holguín (UHo) en Cuba, al cumplimiento de los ODS a partir de la situación actual de la gestión de investigación en Ciencia, Tecnología e Innovación (CTI) y sus resultados en el período 2015-2017. Se utilizó un procedimiento que combina los análisis cualitativo y cuantitativo. Los datos fueron recuperados a través de la triangulación de fuentes de información que provienen de análisis de documentos oficiales del Ministerio de Educación Superior y de la UHo, entrevistas, observaciones y análisis estadístico. Se entrevistaron al vicerrector, director y especialistas en gestión de CTI, presidente del consejo científico asesor, vicedecanos y jefes de proyectos. Dentro del análisis cuantitativo se introduce el cálculo del indicador Coeficiente de Resultados por Proyectos para conocer la contribución de los proyectos a los ODS. Los resultados obtenidos demostraron que la mayor contribución de la UHo es en los objetivos de educación, crecimiento económico e instituciones sólidas y que no se aprovechan las oportunidades del entorno y las potencialidades de su capital humano especialmente en los temas de energías renovables, agua y saneamiento, ciudades y comunidades sostenibles, industria, innovación e infraestructura. Este estudio contribuye a trazar nuevas estrategias que permitan a la UHo anticiparse con mentalidad innovadora a las necesidades del entorno.
Actividad gastroprotectora del extracto etanólico de hojas de Licania platypus (Hemsl.) Fritish.
Authors: Orozco Aguilar Josue , Chavarría Rojas Marianela , Alvarado Barboza Gilbert , Cordero García Eugenia , Morales Acuña Juan Alberto , Retana Salazar Axel , González Camacho Sara
Published: February 2019

La especie Licania platypus, localmente conocida como “sonzapote” se encuentra ampliamente distribuida en países tropicales. Tradicionalmente, en América Central se han utilizado diferentes partes de la planta para diversos problemas de salud, especialmente gastrointestinales. Objetivo: Investigar la posible actividad antiulcerosa gástrica del extracto etanólico de hojas de Licania platypus. Métodos: Las lesiones gástricas fueron inducidas por los modelos de etanol e indometacina. También, se evaluó el extracto con el modelo modificado de Shay. El extracto se administró por vía oral y se midió el área dañada. Además, se analizaron otros parámetros en el modelo de ligadura pilórica. Resultados: La administración oral de una dosis única del extracto (500 mg/kg) redujo significativamente el área de las lesiones gástricas (p < 0.05) en los modelos de inducción de etanol e indometacina. Además, se observó un incremento significativo en la secreción de moco gástrico en el modelo modificado de Shay (p < 0.05). Conclusión: El extracto etanólico de Licania platypus ejerce un efecto gastroprotector en diferentes modelos de inducción de úlceras agudas. Este trabajo brinda la primera evidencia de especies pertenecientes al género Licania con actividad gastroprotectora y permite promover la realización de estudios para elucidar un mecanismo de acción específico.
Sistema integrado de gestión para las IPS de alta complejidad de la ciudad de Barranquilla basado en los estándares de acreditación en salud, el modelo European foundation for quality management y el Balanced Scorecard/Integrated management system for...
Authors: KAFRUNI JÚBIZ NATALY
Published: February 2019

Este artículo presenta el diseño de un Sistema Integrado de Gestión basado en los Estándares de Acreditación en Salud, el EFQM (European Foundation for Quality Management) y el BSC (Balance Scorecard), con el fin de intervenir las necesidades y problemáticas que se presentan durante la prestación del servicio en las Instituciones Prestadoras de Salud de alta complejidad de la ciudad de Barranquilla.Se aplicó como instrumento de recolección de la información, una encuesta dirigida a quince (15) IPS, la cual permitió conocer el estado de gestión de la muestra seleccionada, identificando que a pesar de que se evidencia en la mayoría de las IPS, el compromiso gerencial con la planeación estratégica y la importancia del mejoramiento continuo, una de las principales falencias que se presentan, es el debilitamiento del factor Recursos Humanos, evidenciando la poca motivación y capacitación de los colaboradores.Con la articulación de los tres modelos de gestión se logró obtener una herramienta de gestión efectiva que permite evaluar la gestión integral de la organización, tanto administrativa como operativamente, y de esta forma mejorar la prestación del servicio y garantizar la satisfacción del cliente.
Technical and economic design of a photovoltaic solar test bank for power generation off-grid/Diseño técnico y económico de un banco de prueba solar fotovoltaico para generación de energía eléctrica de forma aislada
Authors: Salas Reyes Yuranis , Gómez Blanco Hismary Ines , Vanegas Chamorro Marley , Valencia Ochoa Guillermo , Villicaña Ortíz Eunice
Published: February 2019

En este artículo se presenta el diseño técnico y económico de un banco de prueba solar fotovoltaico para suministro de energía eléctrica de forma aislada la cual fue motivada principalmente por la importancia que tiene el desarrollo de las energías renovables en la región Caribe colombiana, y la necesidad de implementar en la Universidad del Atlántico un programa integral para la evaluación y aprovechamiento del recurso renovable, en este caso el recurso solar. El proyecto se inicia con el análisis detallado de la información fundamental disponible en las diferentes bases de datos acerca de investigaciones afines, posteriormente se utilizaron datos de radiación solar de la zona de estudio para proceder a aplicar un método de dimensionado del sistema fotovoltaico aislado y por último se realiza el análisis económico del sistema. Los resultados obtenidos muestran que para el diseño de un sistema de este tipo es primordial un análisis de disponibilidad solar en el lugar de la instalación con el fin de dimensionar adecuadamente todos sus componentes y que éste sea apto para funcionar de forma eficiente supliendo la corriente adecuada para mover las cargas tenidas en cuenta en el diseño. El análisis económico indica que se deben tener en cuenta los diferentes incentivos tributarios para que estos proyectos puedan ser viables y se pueda recuperar su inversión en el menor tiempo posible.
Kusma ve hipokalemi ile başvuran çocuk olguda bilateral renal arter darlığı
Authors: GEMİCİ Atilla , ATMIŞ Bahriye , ATMIŞ Anıl
Published: February 2019

Çocuklarda hipertansiyon nedenleri arasında sekonder
nedenler ön plandadır.  Bu nedenle
hipertansiyonun erken tanınması ve tedavi altına alınması, çocukların ilerleyen
yaşlarında yaşam kalitesinin artması ve kronik hastalıklardan korunması açısından
öncelikli hedeftir. Hipertansiyonu olan çocuklar farklı klinik bulgular ile
başvurabilir. Bu yazıda20 gündür olan kusması nedeniyle tetkik edilirken hipokalemi
saptanan, fizik muayene esnasında ölçülen kan basıncı 205/115 mmHg olan ve yapılan
tetkiklerinde bilateral renal arter darlığı tespit edilen 10 yaşındaki erkek
olguyu sunmayı amaçladık. Bu sunumda çocukluk çağında kan basıncı ölçümünün
rutin fizik muayenenin bir parçası olması gerektiğini ve hipertansif çocuk
olguların farklı klinik bulgular ile gelebileceğini vurgulamak, ayrıca
hipertansiyon tanı algoritmasını gözden geçirmek amaçlanmıştır.
Anjioödem
Authors: ERTEKİN Ayşe
Published: February 2019

Anjioödem (AÖ) genellikle subkutan
dokuda belirginleşen, ayrıca solunum ve gastrointestinal sistem submukozal
tabakasında geçici, lokalize ödem ile karakterize bir hastalıktır. AÖ, vücudun
herhangi bir yerinde görülse de en çok ekstremiteler, yüz, genital organlar,
hava yolları ve gastrointestinal sistemde görülür. AÖ tanısı hızlı bir ön
değerlendirme, ayrıntılı anamnez ve fizik muayene ile konulur. Akut atakta
morbidite ve olası mortaliteyi azaltmak için, hastaya en erken zamanda müdahele
edilmelidir.
“RUSSIAN WORLD” PROPAGANDA AS A THREAT TO NATIONAL SECURITY OF UKRAINE
Authors: Zaporozhets O.
Published: February 2019

The article studies the concept “Russian World” in terms of national security of Ukraine. Based on publications of Ukrainian and Russian experts the author shows that the“Russian World” is aimed to justify Russia’s geopolitical ambitions and in particular its dominance in post-soviet countries. According to this project Russia is a unique country-civilization that, due to its historical, cultural and intellectual potential, goes far beyond the state borders. The Russian geopolitical concept is very dangerous for Ukraine because due to historical manipulations the national identity, sovereignty and integrity of the country are artificially devaluated and completely erased. In Russian propaganda Ukraine is labelled as the artificially created country that cannot be the successor of Kievan Rus, doesn’t have its own statehood traditions, culture, language and other attributes of the true nation. Russia tries to appropriate Ukraine’s historical and cultural heritage because without it the RM is ideological construct based on myths that is unable to contribute to strengthening and extending Russia's influence on the international arena.
THE PRINCIPLES OF THE TRANSNATIONAL CRIMINAL LAW IN THE COURSE OF INTERNATIONAL LAW
Authors: Popko V.
Published: February 2019

The article highlights systematic aspects of the major principles of transnational criminal law within the framework of international law transformation. The article is dedicated to the examination of the fundamental principles of international law and international criminal law, in particular, which are viewed systematically and in complex and tight connection with the principles of domestic criminal and criminal procedural law. The necessity of legal enshrinement of its principles is noted. The content of the fundamental principles of criminal law is overviewed, in particular, nullum crimen sine lege (No crime without a previous penal law), principle of individual criminal responsibility, principle of non-reference to the official or professional status of a person, prohibition of repetition of punishment for the same crime under international criminal law, execution of judicial power only by courts, equality of persons before the law and the court, local and temporal principles of criminal law (non-application of terms of limitation, territorial principle of criminal law etc.) Special attention is paid to the content of the universal criminal jurisdiction principle concerning transnational crimes, enshrined in the 2000 UN Convention against Transnational Organized Crime. The author comes to the conclusion that the principles of transnational criminal law are coordinated as between themselves and determine the main characteristics of transnational criminal law and directions of criminal policy.
PRACTICE OF INTERNATIONAL INVESTMENT ARBITRATIONS ON IMPLEMENTATION OF CERTAIN PROVISIONS OF THE ENERGY CHARTER TREATY
Authors: Tropin Z.
Published: February 2019

Practice of international arbitrations on implementation of investment provisions of Energy Charter Treaty («ECT») is considered in the article. Certain investment disputes which appeared on the earliest period of operation of this international agreement are considered. Respectively they are interesting when one would like to forecast application of ECT's provisions. Conclusions of arbitration tribunals in cases Ioannis Kardossopoulos (Greece) v. Georgia, Petrobart Ltd. (Gibraltar) v. Kirgizia, Plama Consortium Ltd. (Cyprus) v. Bulgaria and Nykomb Synergetics Technology Holding AB (Sweden) v. Republic of Latvia are analyzed in the article. Among other things author investigates such problematic issues of implementation of ECT investment provisions as: responsibility of state for the violations performed by state enterprises; interrelation of jurisdiction of national courts and international arbitration tribunals on settlement of international disputes under the ECT; provisional application of ECT and possibility to consider violation of investment provisions on the jurisdictional stage. An author shows that ECT investment arbitrations act on the general trend of investment dispute settlement. On the other hand and taking into account peculiarities and importance of ECT respective decisions may become significant for the general practice of investment dispute settlement.
Fever-induced epileptic encephalopathy in children (FIRES)
Authors: Sсhugareva Ludmila M. , Poteshkina Oksana V. , Kruchina Marina K. , Rusak Mikhail A.
Published: February 2019

Fever infection-related epilepticy syndrome, FIRES — rare severe epileptic encephalopathy infection or fever-induced refractory epileptic status developing in a previously healthy child. The etiology of FIRES remains unknown; post-inflammatory and autoimmune mechanisms are assumed. Recovery is possible, but the majority of children develop significant cognitive failure and refractory epilepsy.
Figurações poéticas da vida rural nas Geórgicas
Authors: Trevizam Matheus
Published: February 2019

Neste artigo, desejamos mostrar que as Geórgicas de Virgílio, embora apresentem evidentes pontos de contato com as práticas rurais em Roma Antiga, não podem ser realmente consideradas um documento sobre a ruralidade romana. Alguns elementos que nos permitem pensar nessa obra, sobretudo, como produto de criação poética são a falta de detalhamento e a “seletividade” dos tópicos que se incorporam à abordagem técnica do “professor”. Além disso, análises feitas por Philip Thibodeau (2011) provam que, embora os cativos não sejam de todo omitidos no âmbito da preceituação de Virgílio, a eliminação do uilicus – administrador rural – permite ao público interagir com o texto de maneira mais decorosa, pondo-se como discipulus na posição de um agricola (“cultivador livre”), não de algum tipo de escravo.

Palavras-chave: poesia didática; agricultura; ficção; poesia; Virgílio.

Keywords:
Evaluación de métodos de extracción de ADN bacteriano en muestras fecales de pacientes diagnosticados con infección por Helicobacter pylori
Authors: García Cuan Aracely , Miranda Cárdenas Anny
Published: February 2019

La identificación de microorganismos a través de técnicas moleculares ha tomado gran popularidad en los últimos años gracias a su precisión. La Reacción en Cadena de la Polimerasa (PCR) es una técnica de diagnóstico molecular sumamente valorada por su rapidez de resultados, alta sensibilidad y especificidad, sin embargo, el rendimiento de esta técnica dependerá de la calidad del ADN extraído. Las muestras fecales contienen una gran cantidad de sustancias, como sales que pueden comportarse como inhibidores para la PCR, por esta razón, se llevó a cabo este estudio donde se evaluaron algunas modificaciones a técnicas de extracción de ADN bacteriano por medio de la metodología fenol-cloroformo en 10 muestras fecales tomadas de pacientes diagnosticados con infección por Helicobacter pylori en el departamento del Atlántico. En el método final se obtuvo una concentración promedio de ADN de 1.501,0 ng/µl.
CONDICIONES DE SALUD Y TRABAJO ASOCIADAS AL DOLOR LUMBAR EN LOS OPERARIOS DEL ÁREA DE PRODUCCIÓN DE UNA EMPRESA DE LÁCTEOS EN BARRANQUILLA
Authors: Arrazola David Mónica , Hoyos Otero Ana , Perdomo Ramos Isaura , Quintero Hernández Karina , Rubio Bravo Mayra
Published: February 2019

Introducción: El dolor lumbar de origen laboral, es considerado uno de los problemas más comunes en salud pública, afectando de tal forma el bienestar y la calidad de vida de los trabajadores. Objetivo: Identificar las condiciones de salud y trabajo asociadas al dolor lumbar en los operarios del área de producción de una empresa de lácteos en la ciudad de Barranquilla. Metodología: El tipo de estudio que se realizó es descriptivo de corte transversal. Se tomó una muestra aleatoria de 80 individuos del área de producción, quienes a través de un consentimiento informado dieron el aval para que se aplicara el Cuestionario Nórdico de autorreporte de molestias o síntomas, instrumento diseñado y validado por Kuorinka. Resultados: Se identificó que el 59% del total de los trabajadores encuestados reportaron dolor lumbar durante el último año, seguido de dolor en muñecas con un 40% del total. El 43% de los trabajadores reporta que el dolor en la columna lumbar les ha impedido realizar actividades en casa o en el trabajo. El 82% de los síntomas reportados por los trabajadores están localizados en la columna lumbar. De los 31 operarios sintomáticos de columna lumbar, el 67.74% este en sobrepeso con IMC igual o mayor a 25. Conclusiones: Los resultados del estudio demuestran que el dolor lumbar es un problema de gran impacto, por ende se deben realizar intervenciones preventivas, enfocadas en mejorar el sistema de trabajo a través del diseño de herramientas y equipos que disminuyan el esfuerzo físico de los trabajadores.
Use of the routine complete blood count to predict steroid resistance in patients with chronic obstructive pulmonary disease
Authors: Kadushkin A. G. , Taganovich A. D. , Movchan L. V. , Shman T. V. , Panasyuk V. K. , Novskaya G. K.
Published: February 2019

The aimof the present study was to investigate the significance of complete blood count, lymphocyte subpopulations, and cytokines in the peripheral blood in order to evaluate steroid resistance in patients with chronic obstructive pulmonary disease (COPD).

Methods.Forty five patients with acute exacerbation of COPD (AECOPD) who underwent bronchoscopy the next day after hospital admission were included in the study. The patients were considered as steroid-sensitive or steroid-resistant according to the ability of dexamethasone to inhibit 50% of interleukin-8 production by alveolar macrophages. Complete blood count, lymphocyte subpopulations, cytokines, immunoglobulin E, and hormone level were measured in the peripheral blood of all patients with COPD.

Results.Macrophage migration inhibitory factor (MIF) level, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) were higher, and absolute and relative eosinophil numbers were lower in steroid-resistant patients with COPD compared to steroid-sensitive COPD patients. Absolute eosinophil number below the cut-off value of 0.126 × 109/L was predictive for steroid resistance with the sensitivity of 83.3%, the specificity of 55.6% and the area under ROC curve (AUC) of 0.677. Relative eosinophil number below 1.2% predicted steroid resistance with sensitivity, specificity and AUC of 83.3%, 63.0%, and 0.751, respectively. NLR, PLR, and MIF higher than 2.75, 116, and 2.24 ng/mL, respectively, predicted steroid resistance with the sensitivities of 66.7%, 61.1%, and 72.2%, respectively; the specificities of 74.1%, 77.8%, and 70.4%, respectively; and the AUCs of 0.731, 0.678, and 0.740, respectively. The combination of relative eosinophil number, NLR and PLR increased the sensitivity to 83.3%, specificity to 77.8%, and AUC to 0.805. The combination of relative eosinophil number, PLR and MIF increased the sensitivity to 83.3%, specificity to 88.9%, and AUC to 0.889.

Conclusion.Steroid-resistant and steroid-sensitive COPD patients differ in absolute and relative eosinophil numbers, LNR, PLR, and MIF level. These parameters could be used to predict steroid resistance in COPD.
Prescribing pattern and adverse drug effects monitoring of anti-rheumatoid drugs in rheumatoid arthritis patients in a tertiary care hospital
Authors: Venkateswaran M. , Dhanasekaran M. , Rajavelu S.
Published: February 2019

Background: Rheumatoid arthritis (RA) is a common disease that causes substantial morbidity in most patients and premature mortality in many. All the drugs used in the treatment of rheumatoid arthritis show significant toxicity and hence it is important to monitor the drugs for adverse drug reaction. This study will estimate the prescribing pattern and bring out the possible adverse drug reactions in patients with rheumatoid arthritis.Methods: This study included 200 patients with rheumatoid arthritis who fulfilled the study criteria were observed for three months. Their prescriptions were collected and analysed. The symptoms of adverse drug reaction were documented through questionnaire. The causality assessment was done by WHO-UMC assessment scale and severity by using modified Hartwig-Seigel severity assessment scale.Results: This study showed most of the patients were female (86%). Majority of them were in age group of 51-60 years. Average number of drugs per prescription was 10.57. Out of 200 patients, 2% were on single DMARD and 50.5% were on two DMARDs. 40% and 7.5% were taking three and four DMARDs respectively. A total of 450 adverse drug reactions were reported, out of which 68.4% due to steroid,12.5% due to DMARDs and 19.1 due to use of NSAIDs, DMARDs and glucocortisteroids. Chloroquine maculopathy occurred in 3 patients and elevated liver enzymes due to methotrexate in 3 patients, which necessitated DMARD withdrawal. Most patients had 1-3 ADRs. 6% of ADRs were severe and 54% belongs to probable category of causality assessment.Conclusions: Treatment of rheumatoid arthritis is mainly based on DMARDs, glucocorticosteroids and NSAIDs. So, occurrence of ADR is much common. Proper monitoring of therapy and timely modification of drugs and lifestyle can reduce the ADR occurrence.
THE EQUIPMENT FOR PRECISE TEMPERATURE MONITORING
Authors: Kazantsev S. A. , Duchkov A. D.
Published: February 2019

The article describes the modern version of the equipment for the autonomous temperature monitoring in boreholes and reservoirs. To characterize the capabilities of the equipment, the results of the long-term measurements of the temperature of Vasyugan swamp (Tomsk region) peatlands and the bottom (water and sediment) of lakes Baikal and Teletskoye are presented.
O que ensinam livros didáticos de Artes do Ensino Médio sobre arte dos povos indígenas
Authors: Thomas Mariana Schnorr , Bonin Iara Tatiana
Published: February 2019

Este artigo discute formas de representação das práticas artísticas dos povos indígenas em dois livros didáticos de Arte para o ensino médio, selecionados para distribuição em escolas públicas por meio do Programa Nacional do Livro Didático de 2015. Sob a perspectiva teórica dos Estudos Culturais em Educação, que orienta o presente estudo, livros didáticos são vistos como artefatos que constituem e propagam conhecimentos e também promovem uma regulação na cultura, à medida que incluem ou excluem aspectos e práticas, nesse caso, dos povos indígenas. A análise mostra que arte indígena é um conceito em disputa, sendo flexionada ora por concepções eurocêntricas, ora por discursos multiculturalistas, quando integrada aos livros didáticos.
Exploring Professional Development for New Investigators Underrepresented in the Federally Funded Biomedical Research Workforce
Authors: Hemming, PhD Japera , Eide Kristin , Harwood Eileen , Ali Ratib , Zhu Zhu , Cutler Jason
Published: February 2019

Objective: The National Research Mentor­ing Network (NRMN) is a strategic partner­ship whose goals include remedying docu­mented disparities by race and ethnicity in the awarding of National Institutes of Health research grants. Our objectives were to offer a profile of early-career investigators who applied to NRMN’s Grantsmanship Coach­ing Programs (GCP) and test for differences in the research productivity, professional obligations, research resources, and motiva­tions of applicants from underrepresented groups (URGs) compared with applicants from well-represented groups (WRGs). We also evaluated how employment at a minority serving institution (MSI) influenced access to research resources and profes­sional obligations.Participants: 880 investigators who submit­ted online applications to join an NRMN GCP between August 1, 2015 and February 1, 2018.Methods: We used two-sample tests of pro­portions and logistic regression to explore differences in applicants’ characteristics and local research environment by group (URG vs WRG) and institution type (MSI vs Other).Results: URG and WRG applicants did not differ in grant application submission history. However, URG applicants had published fewer articles than WRG peers (9.8 vs 15.3, P<.001) and fewer articles as first/last author (4.4 vs 6.9, P<.001). URG appli­cants reported less access to core facilities to conduct research (74% vs 81%, P<.05). Investigators at MSIs reported less access to collaborators (P<.01) and departmental colleagues with federal funding (P<.001) and spent less time on conducting research (P<.001). URGs were more motivated to seek professional development support to expand their peer networks (P<.05) and advance their careers (P<.001).Conclusions: Our findings identified several points of intervention to help applicants from URGs to improve their future chances of obtaining competitive funding.Ethn Dis. 2019;29(Suppl 1): 123-128; doi:10.18865/ed.29.S1.123.
Strategic Opportunities for Leveraging Low-cost, High-impact Technological Innovations to Promote Cardiovascular Health in India
Authors: Prabhakaran Dorairaj , Ajay Vamadevan S. , Tandon Nikhil
Published: February 2019

Accelerated epidemiological transition in India over the last 40 years has resulted in a dramatic increase in the burden of cardio­vascular diseases and the related risk factors of diabetes and hypertension. This increase in disease burden has been accompanied by pervasive health disparities associated with low disease detection rates, inadequate awareness, poor use of evidence-based interventions, and low adherence rates among patients in rural regions in India and those with low socioeconomic status.Several research groups in India have devel­oped innovative technologies and care-delivery models for screening, diagnosis, clinical management, remote-monitoring, self-management, and rehabilitation for a range of chronic conditions. These innova­tions can leverage advances in sensor tech­nology, genomic tools, artificial intelligence, big-data analytics, and so on, for improving access to and delivering quality and afford­able personalized medicine in primary care. In addition, several health technology start-ups are entering this booming market that is set to grow rapidly. Innovations outside bio­medical space (eg, protection of traditional wisdom in diet, lifestyle, yoga) are equally important and are part of a comprehensive solution.Such low-cost, culturally tailored, robust innovations to promote health and reduce disparities require partnership among multi-sectors including academia, industry, civil society, and health systems operating in a conducive policy environment that fosters adequate public and private investments.In this article, we present the unique op­portunity for India to use culturally tailored, low-cost, high-impact technological in­novations and strategies to ameliorate the perennial challenges of social, policy, and environmental challenges including poverty, low educational attainment, culture, and other socioeconomic factors to promote cardiovascular health and advance health equity. Ethn Dis. 2019;29(Suppl 1):145- 152; doi:10.18865/ed.29.S1.145.
Histopathological Changes in the Wistar Rats Liver Treated with Bangle (Zingiber cassumunar Roxb.) Rhizome Ethanol Extract during Acute Toxicity Test
Authors: Handani Kesy Sasta , Utami Wiwien Sugih , Hermansyah Bagus , Normasari Rena
Published: February 2019

Malaria is still an infectious disease that can not be eradicated. The presence of antimalarial drug resistance case encourages the research on herbal plants that are expected to be a complementary therapy drug of malaria, one of them is bangle (Zingiber cassumunar Roxb.). This research aimed to investigate the effect of bangle (Zingiber cassumunar Roxb.) rhizome ethanol extract to the histopathological changes of Wistar rats liver during acute toxicity test. This research type was true experimental laboratories with posttest only control group design using four treatment groups (given dose 42,609 mg/200gBW + Tween 1%, 213,045 mg/200gBW + Tween 1%, 426,09 mg/200gBW + Tween 1%, and 852.18 mg/200gBW + Tween 1%) and one control group (given 1% Tween). Each treatment groups consisted of five male rats and five female rats. The final mean score of hepatocyte damage as the research data was analyzed by One-Way ANOVA test and showed that p=0,084. It indicated that there was no significant difference of liver histopathology results between groups.

 Keywords: malaria, bangle rhizome, acute toxicity test, liver histopathology
Correlation between Quick of Blood and Intradialytic Hypertension on Chronic Kidney Disease Stage V Patients in dr. Soebandi Jember Hospital
Authors: Muharrom Novail Alif , Suryono Suryono , Komariah Cicih
Published: February 2019

Intradialytic hypertension is one of the complications of chronic kidney disease patients (CKD) stadium V undergoing routine hemodialysis. There is still no definite data on incidence of intradialytic hypertension in Indonesia. Therefore, it is important to do further research about the relationship between factors of intraialytic hypertension with incident intradialytic hypertension as preventionefforts morbidity and mortality in patients CKD stadium V undergo hemodialysis. One of the factors is quick of blood (QB). The purpose of this research is to know the connection between QB with intradialytic hypertension on patients PGK stadium V at RSD dr. Soebandi Jember. This research is a type of observational analytic study with cross sectional method which is implemented in the dialysis unit at RSD dr. Soebandi Jember in October 2017. Population and sample in this research are all patients who undergo PGK stadium V routine hemodialysis in RSD dr. Soebandi Jember at a number of 82samples. The data obtained were tested normalitasnya with the Kolmogorov-Smirnov test with the results of the significance of 0.71, indicating the data is distributed normally. Pearson test generates the value of significance (p) 0.032 and strong relationship (r) 0.237 indicating that there is a meaningful relationship with the powerful relationship between weak QB with the incidence of hypertension in patients intradialisis CKD stadium V at RSD dr. Soebandi Jember.

Keywords: CKD, intradialytic hypertension, quick of blood
The Difference Of Visual Acuity And Macular Thickness Post Bevacizumab Therapy In Secondary Macular Edema Retinal Vein Occlusion
Authors: Rahmadani Citra , Fatmawati Nur Khoma , Bakhtiar Rahmat
Published: February 2019

Retinal vein occlusion is the second most common cause of blindness in retinal vascular disease after diabetic retinopathy and may lead to complications of macular edema. Bevacizumab is an influential treatment as an anti vascular endothelial growth factor (VEGF). This study aims to determine the difference of visual acuity and macular thickness before and after treatment of Bevacizumab. This is a quasi experimental study in patients with secondary macular edema retinal vein occlusion who meets the inclusion criteria. Visual acuity and macular thickness were evaluated after one month of treatment. This study was conducted for two months since May-June 2017 by collecting secondary data from medical record at SMEC Samarinda from January 2016 – June 2017. Data were analyzed using Wilcoxon. Sixteen eyes from 16 patients were diagnosed with macular edema secondary retinal vein occlusion given bevacizumab treatment. The mean visual acuity before therapy was 1.106 LogMAR ± 0.509 and increased to 0.889 logMAR ± 0.608 (p = 0.116) after treatment while the mean macular thickness before therapy was 504.06 μm ± 301.273 and decreased to 348.81 μm ± 181.17 (p = 0.017) after treatment. There was a significant effect on the decrease in macular thickness but no significant effect on visual acuity improvement in patients with macular edema secondary retinal vein occlusion at SMEC Samarinda.

 Keywords: Retinal vein occlusion, macular edema, bevacizumab