bluuebunny/crossref_metadata_2025 huggingface dataset:
In Vitro Propagation Method for Production of Phenolic-Rich Planting Material of Culinary Rhubarb ‘Malinowy’
Authors: Wojtania Agnieszka , Mieszczakowska-Frąc Monika
Published: August 2021

Culinary rhubarb is a popular vegetable crop, valued for its long, thickened stalks, very rich in different natural bioactive ingredients. Tissue cultures are a useful tool for vegetative propagation of virus-free rhubarb plants and rapid multiplication of valuable selected genotypes. The aim of this study was to develop an effective method for in vitro propagation of selected genotypes of Polish rhubarb ‘Malinowy’ characterized by high yield and straight, thick and intensive red stalks. Identification and quantification of anthocyanins and soluble sugars by the HPLC method in shoot cultures and ex vitro established plantlets were also performed. Shoot cultures were established from axillary buds isolated from dormant, eight-year-old rhizomes. Effective shoot multiplication of rhubarb ‘Malinowy’ was obtained in the presence of 6.6 µM benzylaminopurine or 12.4 µM meta-topolin. Both cytokinins stimulated shoot formation in a manner that depended on sucrose concentration. Increasing the sucrose concentration from 59 to 175 mM decreased the production of shoots and outgrowth of leaves by 3-fold but enhanced shoot length, single shoot mass and callus formation at the base of shoots. This coincided with increased accumulation of soluble sugars (fructose, glucose) and anthocyanins-cyanidin-3-O-rutinoside (max. 208.2 mg·100 g−1 DM) and cyanidin-3-O-glucoside (max. 47.7 mg·100 g−1 DM). The highest rooting frequency (94.9%) and further successful ex vitro establishment (100%) were observed for shoots that were earlier rooted in vitro in the presence of 4.9 µM indole-3-butyric acid. Our results indicated that anthocyanin contents in leaf petioles were influenced by developmental stage. Under in vitro conditions, it is possible to elicit those pigments by sucrose at high concentration and meta-topolin.
Influence of Modification of the Geometry of the Wave-Plate Mist Eliminators on the Droplet Removal Efficiency—CFD Modelling
Authors: Makowski Łukasz , Łaskowski Jakub , Tyrański Mariusz
Published: August 2021

This study is concerned with droplet separation using wave-plate mist separators. The influence of continuous phase velocity, droplet size, and geometry on droplet removal efficiency has been investigated. The following modifications were analysed: drainage channel presence, length, angle, and modification to the streamlined shape. Furthermore, the influence of the physical parameters of the separated substances on separator efficiency was investigated. Calculations were conducted using computational fluid dynamics (CFD). The results were compared with the experimental data from the literature. Based on the results obtained, a new shape of drainage channels was proposed, which is characterised by high droplet removal efficiency with relatively low pressure drop.
Analysis of the Effects of Process Parameters on Start-Up Operation in Continuous Wet Granulation
Authors: Matsunami Kensaku , Ryckaert Alexander , Peeters Michiel , Badr Sara , Sugiyama Hirokazu , Nopens Ingmar , De Beer Thomas
Published: August 2021

Toward further implementation of continuous tablet manufacturing, one key issue is the time needed for start-up operation because it could lead to lower product yield and reduced economic performance. The behavior of the start-up operation is not well understood; moreover, the definition of the start-up time is still unclear. This work investigates the effects of process parameters on the start-up operation in continuous wet granulation, which is a critical unit operation in solid drug manufacturing. The profiles of torque and granule size distribution were monitored and measured for the first hour of operation, including the start-up phase. We analyzed the impact of process parameters based on design of experiments and performed an economic assessment to see the effects of the start-up operation. The torque profiles indicated that liquid-to-solid ratio and screw speed would affect the start-up operation, whereas different start-up behavior resulted in different granule size. Depending on the indicator used to define the start-up operation, the economic optimal point was significantly different. The results of this study stress that the start-up time differs according to the process parameters and used definition, e.g., indicators and criteria. This aspect should be considered for the further study and regulation of continuous manufacturing.
Integration of Regression Analysis and Monte Carlo Simulation for Probabilistic Energy Policy Guidelines in Pakistan
Authors: Sajid Zaman , Javaid Asma , Khan Muhammad Kashif , Sadiq Hamad , Hamid Usman
Published: August 2021

Forecasting energy demand and supply is the most crucial concern for energy policymakers. However, forecasting may introduce uncertainty in the energy model, and an energy policy based on an uncertain model could be misleading. Without certainty in energy data, investors cannot quantify risk and trade-offs, which are compulsory for investments in energy projects. In this work, the energy policies of Pakistan are taken as a case study, and flaws in its energy policymaking are identified. A novel probabilistic model integrated with curve fitting methods was proposed and was applied to 17 different energy demand and supply variables. Monte Carlo simulation (MCS) was performed to develop probabilistic energy profiles for each year from 2017 to 2050. Results show that the forecasted energy supply of Pakistan in the years 2025 and 2050 would be 70.69 MTOE and 131.65 MTOE, respectively. The probabilistic analysis showed that there is 14% and 6% uncertainty in achieving these targets. The research shows the expected energy consumption of 70.33 MTOE and 189.48 MTOE in 2025 and 2050, respectively, indicating uncertainties of 65% and 31%. Based on the results, eight energy policy guidelines and recommendations are provided for sustainable energy resource management. This study recommends developing a robust and sustainable energy policy for Pakistan with the help of transparent governance.
Bitcoin as an Investment and Hedge Alternative. A DCC MGARCH Model Analysis
Authors: Rudolf Karl Oton , Ajour El Zein Samer , Lansdowne Nicola Jackman
Published: August 2021

Volatility and investor sentiment have been factors for the slow adoption rate of Bitcoin (BTC) that was first recognized in 2008 as a potential store of value, investment vehicle and a hedge alternative to gold during a recession. The purpose of this applied mathematics study will use a multivariate DCC GARCH model. Bitcoin holds its ground in volatility. This study examines Bitcoin as an investment and hedge alternative to gold as well as the major stock index. To perform the research to explore the viability of Bitcoin as an investment and hedge alternative to gold, the authors conducted a DCC GARCH model analysis. The findings of this research paper confirm Bitcoin’s cyclical performance between volatility and adoption. The findings give a strong ground for Bitcoin as the new digital currency, store of value, medium of exchange, and a unit of account and incentivize further research by theorists, scholars and examiners. The significance of this applied mathematics research and analysis will allow an unstoppable, incorruptible, and uncontrollable store of value, and investment vehicle, without governmental or institutional intervention. This study contributes by comparing and contrasting volatility stability based on the return levels of each Bitcoin on major indexes traded with BTC (based on fiat currencies) and gold.
Robert B. Sim—Tribute
Authors: Erdei Anna
Published: August 2021

I met Bob in 1985, when I moved with my family to Oxford for a two-year EMBO fellowship at the MRC Immunochemistry Unit [...]
Viral Toxin NS1 Implication in Dengue Pathogenesis Making It a Pivotal Target in Development of Efficient Vaccine
Authors: Lebeau Grégorie , Lagrave Alisé , Ogire Eva , Grondin Lauriane , Seriacaroupin Soundary , Moutoussamy Cédric , Mavingui Patrick , Hoarau Jean-Jacques , Roche Marjolaine , Krejbich-Trotot Pascale , Desprès Philippe , Viranaicken Wildriss
Published: August 2021

The mosquito-borne viral disease dengue is a global public health problem causing a wide spectrum of clinical manifestations ranging from mild dengue fever to severe dengue with plasma leakage and bleeding which are often fatal. To date, there are no specific medications to treat dengue and prevent the risk of hemorrhage. Dengue is caused by one of four genetically related but antigenically distinct serotypes DENV-1–DENV-4. The growing burden of the four DENV serotypes has intensified both basic and applied research to better understand dengue physiopathology. Research has shown that the secreted soluble hexameric form of DENV nonstructural protein-1 (sNS1) plays a significant role in the pathogenesis of severe dengue. Here, we provide an overview of the current knowledge about the role of sNS1 in the immunopathogenesis of dengue disease. We discuss the potential use of sNS1 in future vaccine development and its potential to improve dengue vaccine efficiency, particularly against severe dengue illness.
Prevalence and Drivers of COVID-19 Vaccine Hesitancy among Czech University Students: National Cross-Sectional Study
Authors: Riad Abanoub , Pokorná Andrea , Antalová Natália , Krobot Martin , Zviadadze Nutsa , Serdiuk Iryna , Koščík Michal , Klugar Miloslav
Published: August 2021

Background: university students are believed to retain the highest levels of health literacy. They are perceived as the opinion leaders within their communities; therefore, their health-related beliefs and attitudes are deemed important for public health campaigns. This study aimed to investigate the COVID-19 vaccine hesitancy drivers among university students in the Czech Republic. Methods: a cross-sectional study using a self-administered questionnaire was carried out in the weeks before the unrestricted vaccine deployment to Czech adults. The questionnaire had 21 multiple-choice items stratified in 4 categories; demographic characteristics, COVID-19-related anamnesis and influenza vaccine experience, attitudes towards COVID-19 vaccination, and the possible drivers of COVID-19 vaccine hesitancy suggested by the WHO-SAGE. Results: out of the 1351 included students, 66.8% were females, 84.5% were Czech nationals, and 40.6% enrolled in healthcare programs. The overall COVID-19 vaccine acceptance level was 73.3%, 19.3% of participants were vaccine-resistant, and only 7.4% were vaccine-hesitant. Trust in the pharmaceutical industry, trust in healthcare providers, and perceived knowledge sufficiency predicted higher odds of vaccine acceptance. In contrast, media and social media, personal beliefs, immunity misconception, previous COVID-19 infection, and suspicions about novel vaccines and the local availability predicted higher odds of vaccine hesitancy. Conclusions: The findings of this study predict a fair probability to achieve community immunity (herd immunity) among the target population group. The primary prevention strategies in the Czech Republic need to be culturally sensitive and inclusive for foreign nationals. As one-quarter of the participating students are dependent on vaccine safety data, this study findings support the call for independent studies evaluating the side effects of COVID-19 vaccines.
Advantages and Disadvantages of Using e-Learning in University Education: Analyzing Students’ Perspectives
Authors: Al Rawashdeh Alaa Zuhir , Mohammed Enaam Youssef , Al Arab Asma Rebhi , Alara Mahmoud , Al-Rawashdeh Butheyna , Al-Rawashdeh Butheyna
Published: August 2021

: The architecture of a learning system implies a heavy task for e-learning to be integrated into a complicated system that is flexible, time scalable, and capable of lasting, even though there are many diverse tools. Currently, higher education in United Arab Emirates is experiencing a major transformation, considering increased accessibility. Therefore, the study aims to identify the advantages and disadvantages of e-learning in university education in United Arab Emirates. A descriptive study design was used to randomly select students from Ajman university, who were enrolled in 2018/2019 academic year. A close-ended structured questionnaire was constructed to collect data from students. Frequencies and percentages were used to analyse the data collected. 81% students stated that e-learning provides scientific material in an interesting way. Similarly, 80% students have responded that e-learning increases the possibility of contact between students among themselves and between the students and the teacher. 73% students indicated that due to increasing social isolation, they spend more time in front of the technical means of social interaction account and face-to-face with others. 70% students have indicated that there is a presence of electronic illiteracy among parents, which reduces their ability to follow their children electronically. It is essential for potential e-learners to understand the differences between an e-learning classroom setting and a conventional classroom setting as there are both advantages and disadvantages of e-learning to both environments that can probably influence their overall performance as a student.
The Convergence of Online Teaching and Problem Based Learning Modules amid the COVID-19 Pandemic
Authors: Bumblauskas Daniel , Vyas Nick
Published: August 2021

There is a convergence unfolding between two formerly unique and separate areas of teaching research methodology: distance education and problem-based learning (PBL) environments.  Much has been published on each field independently, however, in the modern-era of online, distance, and hybrid educational programs there is a need for more case and experiential-based learning activities which can effectively measure stated learning objectives.  Trends in education have led to the development of various methods to instruct courses and conduct research online. Teaching research methodology and pedagogy have evolved to include video capture, remote conferencing, and other real-time communications techniques allowing faculty and students to collaborate across great distances. Meanwhile, PBL environments have been used extensively in teaching medicine, clinical practice, law, business/management, and many other disciplines to improve student learning.  This has been further accelerated during the COVID-19 pandemic through the use of technologies like Zoom, WebEx, GoToMeeting, Google Hangout Meet, etc. and the availability of PBL-ready environments in breakout rooms and asynchronous simulated projects.  Student preference data from 2020 are reported as part of this study.  One example of this merger between online delivery and PBLs was the development of a PBL statistical process control (PBL-SPC) module.  A cross-functional academic team was created across both a college of business and college of education in which a PBL-SPC module was developed based on a real-life situation in which students immerse themselves in a potato chip factory environment.  The motivation for the PBL-SPC was that this is a challenging topic to cover which students often find difficult to relate to and/or boring.  Three different scenarios were developed and students, as individuals or in teams, must traverse the simulated factory to assess the situation.  Learning outcomes are measured by the course instructors and the PBL environment is being used by faculty around the world. Additionally, the PBL-SPC module has now been scaled to other applications such as six-sigma simulated project training during the COVID-19 pandemic. Pedagogical methods should be interactive, stimulate learning, improve the learning outcomes / critical thinking, and enhance student experience. This paper proposes that merging the effective and tech-friendly pedagogical methods of PBL-SPC, with the right modalities and model of online delivery, can help achieve these aforesaid goals. Even more, it can deliver a great opportunity to educators and institutions worldwide for advancing the reach of education.
Attitudes and Practices of Educators Towards e-Learning During the COVID-19 Pandemic
Authors: Karasneh Reema , Al-Azzam Sayer , Muflih Suhaib , Hawamdeh Sahar , Muflih Mohammad , Khader Yousef
Published: August 2021

Background The novel coronavirus outbreak is now shifting the way educational institutions operate around the world. This study aims to assess the online learning experience during the pandemic and recognize its perceived barriers according to university professors in Jordan. Methods This is a questionnaire-based, cross-sectional, and descriptive study. A web-based survey was distributed to all university professors and lecturers in public universities across Jordan. Results A total of 508 educators responded to this study. Males (67.5%, n=343) dominated the study population compared to females (32.5%, n=165). Educators spent an average of 20.2 ± 15.9 hours/week using the internet for educational purposes during the pandemic. Positive attitudes towards online teaching were seen, as 65.7% reported being prepared for online teaching, while 40.8% were comfortable communicating with students via online platforms. Institutional support for online learning also appears to have increased following the coronavirus outbreak. An overwhelming majority (81.9%, n=416) stated that their universities supported online education during the pandemic, compared to 56.5% (n=287) before. The main recognized barriers for online teaching were poor internet connection (78.3%, n=398), disadvantages in old learning tools (e.g., uploading capacity) (70.9%, n=360), and family atmosphere (69.3%, n=352). Participants also recognized technical (74.0%, n=376) and computer skills (49.2%, n=250) as areas requiring development. Conclusion Despite the positive attitudes of educators towards online teaching, many barriers need to be overcome before the shift from traditional learning is implemented. Faculty training and inter-departmental communication are warranted for the success of online teaching during the COVID-19 pandemic.
Psychology in kilaviyal – Kalithogai
Authors: P Thamilarasi , P Sumana
Published: August 2021

Kilavi - individual word is combined to form a language. Communication took place even when language did not originate and develop. In the early days, he changed the information by making sounds, smoking and gestures. Language is still a tool to convey its opinion to others. The concept of a man's characteristic interests revolves among the community through the words he can speak.  Man is distinguished from other species by his ability to speak and discern. The thoughts in the heart take the form of sound and become the language. This language has many internal material concepts.
The Influence of Corporate Governance and Investment Opportunity Set on Firm Value: CSR as Moderating Variable
Authors: Weni Weni Apriliana , Yulia Yosi , Sanjaya Sigit
Published: August 2021

AbstractThe object of this study is a manufacturing company listed on the Indonesia Stock Exchange for the period 2016-2020 with a total population of 196 companies. The sample of this research is 44 companies that meet the criteria based on purposive sampling. The analysis technique uses multiple linear regression.The results of this study there is a significant relationship between the independent board of commissioners on firm value. Institutional ownership has no effect on firm value. There is a significant relationship between the audit committee and the investment opportunity set on firm value. The results of other studies indicate that there is an influence of the CSR moderating variable between the independent board of commissioners' relationship to firm value. It is different with institutional ownership that has no effect on the value of the company which is moderated by CSR. There is a significant effect between the audit committee and the investment opportunity set on firm value moderated by CSR in manufacturing companies listed on the Indonesia Stock Exchange for the 2016-2020 period.Keywords: CSR, independent board of commissioners, investment opportunity set, institutional ownership. audit committee, firm value.
On Commandment as Refuge: Exploring the Politics of Health and Indigenous African Religion on Covid-19
Authors: Molapo Sepetla
Published: August 2021

This paper explores the significance of the turn to the religion of the family and the clan (i.e., indigenous African religion) taking place under the contemporary conditions of Covid-19 in many African countries. It does this in order to exhibit the Africanity that is hidden by this otherwise pragmatic turn. The paper explores this Africanity by drawing from the classical African story of Seila-Tsatsi, which it argues has its roots in religious education. The key aim of its examination of this Africanity is interrogate a politics of health it claims the World Health Organisation advances. The paper does not explore this turn by accounting for the meanings individuals attribute to it but is rather abstract and conceptual in its approach. The argument it makes is that the contemporary turn to the religion of the family and the clan exhibits desire for an inclusive form of relationality that ought to inform fair, equitable and just health outcomes. It argues that the WHO’s politics of health is blind to this model because it stubbornly upholds binary thought.
Reflections on the proceedings of the 19th Congress of the Chinese Communist Party (CCP) on Sino-Africa and Sino-BRICS relations
Authors: Phaahla Elias
Published: August 2021

Beijing’s economic diplomacy has, since the dawn of the millennium, sought to reconfigure the world by championing a new economic order that is predicated on the principles of multipolarity and fairness. The last policy conference of the Chinese Communist Party (CCP) shed some light into how these policy ideals are to be carried out by Beijing and how they will bear on her relationship with countries from the Global South. This paper considers the policy statements of the CCP during its 19th congress held in October 2017 as a sneak peek into the future of China’s economic diplomacy and the implications for Africa’s own economic future from the context of Brazil, Russia, India, China and South Africa (BRICS). It argues that China’s role as the leader of the BRICS fulcrum reflects her goal to have a global influence that will see erstwhile economic backwaters such as Africa turning their focus away from the West to the East in search of sustainable solutions to their economic challenges.
The Responsibility of Government and Society Towards Social Cohesion: A Family Perspective
Authors: Bidandi Fred
Published: August 2021

Social cohesion, the foundation that keeps society together, is influenced by various inter-related factors such as education social, cultural, religious, and business, among others. Current debates indicates that unless social cohesion in its various dimensions is addressed, be it through reconciliation, tackling inequality, crafting a national identity, or bridging rural-urban divides, the implementation of any Southern African Development Plan will be challenging. In this paper, social cohesion is viewed as an intervention for coexistence; as an invitation to find common ground and allowing the sharing of social spaces; and to forge a common identity whilst recognising societal diversity. This paper postulates that although social cohesion is intended to contribute towards nation-building and national unity, government policies are fundamental to the advancement thereof. The paper defines, unpacks, and identifies the challenges of social cohesion using South Africa as a case study. The paper argues that the family is instrumental in building social cohesion. Government through its policies processes has an important role to play in strengthen the family. The lessons learnt could contribute to the role of family towards social cohesion on the African continent.
Manufacturing Consent Revisted: China’s image in selected South African media in the opening phase of the Covid-19 pandemic
Authors: Pillay Anton
Published: August 2021

The absence of any real substantial critique of China in South Africa media in the aftermath of Covid-19 is cause of concern given the increasing evidence to suggest that China is exporting its authoritarian press censorship culture abroad. South Africa, a strategic partner of China, offers insight into this “export.” In developing a methodology which asks if “China is crafting its image”, this research examines a sample of South African media between March- July 2020 to ascertain if censorship occurred. Deploying the theoretical framework of the Propaganda Model (PM) developed Herman and Chomsky’s “Manufacturing Consent” theory, the research cross analyzes via five filters to determine if China is “Manufacturing Consent” within the South African media.
ADMINISTRATIVE-TERRITORIAL REFORM: TRANSFORMATION OF LOCAL SELF-GOVERNMENT IN THE REGIONAL CONTEXT (A CASE STUDY OF THE UDMURT REPUBLIC)
Authors: Yamilov R.M.
Published: August 2021

Within the framework of this article, the transformation of local self-government in the regional context (on the example of the Udmurt Republic) is considered with some reservations. Two main tasks of the administrative-territorial reform are identified: the unification of municipal districts into enlarged municipal districts; and the level-by-level reconfiguration of management processes based on functional optimization. It is proposed to create six enlarged municipal districts in the Udmurt Republic. Mixed municipal areas are identified as a result of the combination of urban settlements and rural areas. Excessive administrative-territorial management in relation to rural areas of the Udmurt Republic is revealed. An enlarged scheme of functional optimization of administrative processes of administrative-territorial management is proposed. Quantitative optimization and qualitative (functional) optimization of administrative-territorial management are distinguished. The necessity of a single digital management platform as the basis of administrative-territorial reform is shown. The transition from a fractal management system to an antifractal management system is proposed through the functional optimization of management processes, in relation to which administrative and territorial management should be built. The necessity of compliance of administrative-territorial reform with digital management is shown. Brief examples of functional optimization in relation to regional educational social processes and in relation to regional agricultural social processes are given. The possible reduction of budget expenditures by 5.8 billion rubles relative to the expenditures of the consolidated budget of the Udmurt Republic for 2019 is calculated, which is 5.99 % of this budget in the traditional version of the regional reconfiguration of management processes
THE CONCEPT AND STRUCTURE OF THE IMPLEMENTATION OF PROSECUTOR's SUPERVISION OVER THE ACTIVITIES OF LAW ENFORCEMENT AGENCIES
Authors: Nasonov A.A. , Nasonova O.A.
Published: August 2021

The article proves that the concept of "Prosecutor's supervision over the activities of law enforcement agencies" is used in several aspects. This approach allows us to consider this phenomenon as a system of norms regulating public relations for checking the implementation of laws by law enforcement agencies; as criminal procedural relations; as criminal procedural activities of the prosecutor's office. The article examines the structure of the implementation of prosecutor's supervision over law enforcement agencies, which includes the following elements: the subject of implementation, the object of implementation, the means of implementation. Arguments are given in favor of the fact that the object of implementation of the prosecutor's supervision over the activities of law enforcement agencies is the activities of the prosecutor's office aimed at verifying the accuracy of the law enforcement agencies, including the application of measures of the prosecutor's response to them. The subject of implementation of the prosecutor's supervision of law enforcement agencies, which is represented by the prosecutor's office, is being studied. The article describes the means of implementing prosecutor's supervision over the activities of law enforcement agencies. The definition of this implementation process is formulated and its features are revealed, which include: the course of this implementation within the framework of prosecutor-supervisory relations; implementation in the interests of society, the state and the individual; manifestation in the form of lawful actions; reliance on a complex legal framework, the core of which is the Law on the Prosecutor's Office.
Evaluation of the Kostroma Breed Bull-Sires According to the Genotypes of Casein and Fertilizing Ability
Authors: Королев А.А. , Баранова Н.С.
Published: August 2021

Представлен анализ носительства ценных генотипов по каппа-казеину (ВВ) и бета-казеину (А2А2) у быков-производителей костромской породы. У этих быков изучена их оплодотворяющая способность. Материалом для исследования послужили геномные паспорта, племенные свидетельства на быков-производителей костромской породы и базы СЕЛЭКС двух племенных хозяйств. Быки заводских линий имеют относительно невысокую кровность по бурой швицкой породе (от 7 до 41%). Носителями ценного генотипа для производства сыра (ВВ) являются 11 быков (55,0%). Генотип по бета-казеину А2А2 выявлен у 9 быков (45,0%). Быки-производители Лечо 667, Кагор 41, Клим 996, Залив 9220, Маневр 8589 имеют одновременный гомозиготный генотип по каппа-казеину (ВВ) и бета-казеину (А2А2). Среди быков костромской породы отсутствуют генотипы по каппа-казеину (AA) и бета-казеину (А1А1). Для характеристики оплодотворяющей способности семени брали данные по быкам, семенем которых осеменено не менее 80–100 коров и тёлок. Быки-производители Буран 95 и Залив 9220 имели высокие индексы осеменения тёлок (1,5–1,6) в обоих хозяйствах. В племенном хозяйстве СПК «Гридино» высокий индекс осеменения коров выявлен у быка Залива 9220 (1,6), что превосходит показатели (при Р < 0,01) других быков: Бурана 95 (на 0,2) и Лечо 667 (на 0,4). Данные исследования могут использоваться при закреплении быков-производителей в хозяйствах с целью совершенствования качественных показателей молока, необходимых для производства сыра и молочных продуктов.

The analysis of valuable genotypes carrier by kappa-casein (BB) and beta-casein (A2A2) in bull-sires of the Kostroma breed is presented. The fertilizing ability of these bulls has been studied. The material for the study was genomic passports, breeding certificates for bulls-sires of the Kostroma breed and CELEX bases of two breeding farms. Bulls of factory lines have a relatively low blood along the Brown Swiss breed (from 7 to 41%). The carriers of the valuable genotype for cheese (BB) production are 11 bulls (55.0%). The beta-casein genotype A2A2 was found in 9 bulls (45.0%). Bull-sires Lecho 667, Kagor 41, Klim 996, Zaliv 9220, Manevr 8589 have a simultaneous homozygous genotype for kappa-casein (BB) and beta-casein (A2A2). Among the bulls of the Kostroma breed, there are no genotypes for kappa-casein (AA) and beta-casein (A1A1). To characterize the fertilizing ability of the semen, data on bulls were taken, the semen of which was inseminated at least 80–100 cows and heifers. Bull-sires Buran 95 and Zaliv 9220 had high insemination indices for heifers (1.5–1.6) in both farms. In the breeding farm of the APC Gridino, a high cow insemination index was found in the bull Zaliv 9220 (1.6), which exceeds the indicators (at P < 0.01) of other bulls: Buran 95 (by 0.2) and Lecho 667 (by 0.4). The research data can be used in fixing bull-sires in farms in order to improve the quality indicators of milk necessary for the production of cheese and dairy products
Effects of Veterinary Preparations Based on Microelement Nanoparticles on Animal Health and Product Quality
Authors: Лебедева Т.И. , Красочко И.А. , Красочко П.А.
Published: August 2021

При интенсивном развитии животноводства и ветеринарной медицины от фармацевтической отрасли требуется создание новых эффективных ветеринарных препаратов, направленных на поддержание биохимических механизмов гомеостаза и повышение продуктивности у животных. При этом большая роль отводится макро- и микроэлементам, поступающим в организм животным. Однако в составе различных кормовых и витаминно-минеральных добавок эти вещества не всегда полностью усваиваются организмом и не оказывают должного воздействия на органы и системы. Макро- и микроэлементы способны значительно изменять свои химические свойства и реакционную способность в зависимости от количества атомов – в виде наночастиц, которые обладают высокой химической активностью и способны вступать в реакции с другими веществами фактически без участия дополнительной энергии. Препараты, содержащие наночастицы макро- и микроэлементов, по сравнению с традиционными формами, обладают экологичностью, биодоступностью и эффективностью действия при использовании на практике. Препараты на основе наночастиц металлов являются альтернативой использования антибиотиков, не способствуют эволюции бактерий и возникновению резистентности, а вновь созданные ветеринарные препараты и кормовые добавки на основе наноструктур жизненно важных для организма животных химических элементов позволят более эффективно и с наименьшими затратами лечить и профилактировать многие болезни у животных, а также получать больше продукции животноводства с наименьшими экономическими затратами.

With the intensive development of animal husbandry and veterinary medicine, the pharmaceutical industry requires the creation of new effective veterinary drugs aimed at maintaining the biochemical mechanisms of homeostasis and increasing productivity in animals. At the same time, a large role is given to macro- and microelements entering the body of animals. However, in the composition of various fodder and vitamin-mineral supplements, these substances are not always fully absorbed by the body and do not have a proper effect on organs and systems. Macro- and trace elements are able to significantly change their chemical properties and reactivity depending on the number of atoms – in the form of nanoparticles, which have high chemical activity and are able to react with other substances with virtually no additional energy. Preparations containing macro- and trace-element nanoparticles, compared to traditional forms, have environmental friendliness, bioavailability and effectiveness when used in practice. Preparations based on metal nanoparticles are an alternative to the use of antibiotics, do not contribute to the evolution of bacteria and the emergence of resistance, and newly created veterinary drugs and feed additives based on nanostructures of chemical elements vital to the animal body will more effectively and with the least cost treat and prevent many diseases in animals, as well as receive more livestock products with the lowest economic costs.
A survey: blockchain utilization for securing healthcare system
Authors: DADVAR Elnaz , KALKAN Kubra
Published: August 2021

Nowadays healthcare systems have started to be integrated with Internet of Things (IoT) in order to deliver some benefits in diagnosis and treatment process, such as remote patient monitoring and data usage for analytics and fast treatment. With the rise of IoT healthcare devices, number of electronic health records are increased to a rate that it is estimated to exceed billions in the next few years. Although cloud computing is a practical solution for processing this kind of data, healthcare records contain confidential and sensitive patient data which makes this system very vulnerable to the security and privacy threats, so it needs more investigation. For making this critical information more secure, researchers have come up with a solution of applying blockchain technology in healthcare. In this paper, we review the latest literature of blockchain application in healthcare from the security and privacy perspective. Several existing works have been discussed and a comparative study is done among the published works, along with potential future perspectives.
Faktor-Faktor Yang Berhubungan Dengan Motivasi Pasien Kanker Menjalani Kemoterapi Di Rumah Sakit X
Authors: Banga Allo Kartika
Published: August 2021

Kanker merupakan penyakit kronis yang membutuhkan penanganan yang kompleks dan cukup panjang. Salah satu terapi kanker adalah pemberian kemoterapi yang sering menumbulkan efek samping, sehingga pasien membutuhkan motivasi dalam terapi. Tujuan penelitian   untuk menganalisis faktor-faktor yang berhubungan dengan motivasi pasien kanker menjalani kemoterapi.   Desain penelitian cross sectional dengan pendekatan deskriptif kolerasional. Sampel sebanyak 40 orang pasien kanker yang menjalani kemoterapi, diambil secara  total sampling dengan purposive sampling. Alat pengumpul data berupa kuesioner. Hasil Univariat mayoritas usia responden ? 47 tahun yaitu sebanyak 55%, jenis kelamin perempuan sebanyak 100%, pengetahuan baik sebanyak 85%, memiliki efek samping sebanyak 100%, siklus kemoterapi ? 4 siklus sebanyak 57%, dukungan keluarga baik sebanyak 85%, dukungan perawat baik sebanyak 90%, motivasi kuat sebanyak 77,5%.   Hasil Uji Bivariat Chi-Squre didapatkan secara statistik terdapat hubungan antara dukungan perawat dengan motivasi pasien kanker menjalani kemoterapi di Rumah Sakit X p=0,000 (p<0,05); tidak ada hubungan  yang signifikan antara usia p=0,258, pengetahuan    p=0,884,   siklus kemoterapi   p=0,328,   dan dukungan keluarga   p=0,634: (p>0,05) dengan motivasi menjalani kemoterapi. Simpulan, dukungan perawat   berhubungan dengan motivasi pasien kanker yang menjalani kemoterapi. Sarannya perawat mengembangkan kemampuan dan pengetahuan terkait manajemen pasien kemoterapi sehingga dapat memberikan motivasi bagi pasien kanker menjalani kemoterapi.
PERAN TOKOH AGAMA DALAM PECEGAHAN PENULARAN COVID-19
Authors: Prasetyaningrum Oktalia
Published: August 2021

Kasus positif infeksi Virus Corona 19 di Indonesia masih menunjukkan pertambahan dari hari ke hari. Terdapat 161 kasus ODP dan 3 kasus PDP pada 22 Maret 2020 di Kabupaten Gunungkidul, Yogyakarta dan dan  meningkat dengan angka hampir mencapai 700 kasus  dengan  695 kasus merupakan ODP pada 1 April 2020. Jumlah tersebut menjadi yang tertinggi di Yogyakarta. Fenomena peningkatan angka kejadian infeksi COVID-19 tersebut tentu menjadi kekhawatiran Pemerintah Indonesia dan masyarakat, oleh karena itu diperlukan metode-metode dan pendekatan kepada masyarakat guna mencegah penularan infeksi virus. Salah satu metode yang dapat dilakukan adalah pendekatan kepada masyarakat melalui tokoh agama. Kenyataanya di masyarakat, seringkali peran tokoh agama kurang optimal dilaksanakan dalam pembinaan masyarakat. Terbukti masih ada beberapa kelompok masyarakat yang menggelar ibadah secara berkelompok dalam masa pandemic COVID-19 secara sembunyi-sembunyi. Metode penelitian ini adalah kuantitatif deskriptif  dengan  112 responden melalui tehnik accidental sampling.  Penelitian dilakukan pada Bulan Juni 2020 di Yogyakarta dengan alat ukur kuesioner dalam bentuk formulir online. Analisa univariate dilakukan dengan komputerisasi. Hasil penelitian menunjukkan bahwa sebanyak 92,85% responden masuk dalamkategori peran optimal. Saran: melibatkan tokoh agama dalam mengkampanyekan program pencegahan penularan COVID-19
Kerja Sambilan Mempengaruhi Ketidakhadiran Pelajar Tingkatan 3
Authors: Mat Daud Nurul Farhana , Mat Yusoff Nur Asma Suzianti , Mohd Azmi Nurul Hazlin , Mohd Asri Siti Zulaikha Khairunnisa , Manisha Zaidi Nur Zalikha , Husin Moh Razimi
Published: August 2021

Gejala ponteng sekolah semakin hari semakin menular dalam kalangan pelajar di sekolah. Walaupun kita sudah mencapai era globalisasi, namun gejala ponteng ini amat sukar untuk diatasi. Oleh sebab yang demikian, satu kajian telah dijalankan terhadap masalah ponteng yang berlaku di sebuah Sekolah Menengah sekitar Kepong, Kuala Lumpur. Kajian ini bertujuan untuk mengenal pasti faktor kerja sambilan dan faktor lain punca pelajar ponteng sekolah. Selain itu, kajian ini juga dijalankan bertujuan untuk menghuraikan kesan-kesan gejala ponteng kepada pelajar dan sekolah serta menjelaskan langkah-langkah yang boleh diambil untuk mengurangkan gejala ponteng dan mengenalpasti tindakan yang diambil oleh pihak sekolah terhadap pelajar yang terlibat dalam gejala ponteng sekolah. Penyelidik menggunakan kaedah kajian temubual semi struktur bersama seorang responden yang merupakan guru disiplin di sekolah tersebut. Hasil kajian menunjukkan bahawa peringkat umur pelajar yang kerap ponteng adalah pelajar dari tingkatan 3. Dapatan kajian menunjukkan faktor utama pelajar ponteng ialah faktor kerja sambilan dan faktor sikap pelajar, faktor latar belakang, serta faktor rakan. Dapatan kajian juga menunjukkan bahawa peranan ibubapa, peranan sekolah serta peranan media massa merupakan langkah yang boleh diambil bagi mengatasi masalah tingkah laku ponteng sekolah.

Part -Time Work Affects Absenteeism the Student Form 3

Abstract: Symptoms of skipping school are becoming more and more contagious among students at school. Although we have reached the era of globalization, but this symptom of skipping is very difficult to overcome. For this reason, a study was conducted on the problem of skipping that occurred in a Secondary School around Kepong, Kuala Lumpur. This study aims to identify the factors of part -time work and other factors that cause students to skip school. In addition, this study was also conducted to describe the effects of truancy symptoms to students and schools and explain the steps that can be taken to reduce truancy symptoms and identify actions taken by the school against students involved in truancy symptoms. The researcher used a semi -structured interview research method with a respondent who is a discipline teacher in the school. The results showed that the age group of students who often skipped were students from Form 3. The findings showed that the main factors of students skipping were part -time work factors and student attitude factors, background factors, as well as peer factors. The findings also show that the role of parents, the role of the school and the role of the mass media are steps that can be taken to overcome the problem of skipping school behavior.

Keywords: Part-Time Work, Student Form 3, Absenteeism.
Automatic Detection of 3D Joint Erosion in Hand HR-pQCT: A Level Set-Based Approach
Authors: Zhang Xuechen , Cheng Isaac , Liu Shaojun , Li Chenrui , Xue Jinghao , Tam Laishan , Yu Weichuan
Published: August 2021

In this paper, we propose a 3D fully automatic joint erosion algorithms for hand HR-pQCT, and its performance can reach consensus with human specialist.
A inter-relação do acidente de consumo e assistência à saúde: revisão integrativa
Authors: Lima Thaís Pereira , Sousa Thais Vilela de , Bezerra Maria Luiza Rêgo , Carvalho Filha Francidalma Soares Sousa , Lima Lucas Monteiro , Vilanova Jaiane de Melo , Pereira Mayara Cândida , Moraes Filho Iel Marciano de
Published: August 2021

Objetivo: Analisar a produção científica acerca da inter-relação entre consumidor, produto e assistência à saúde. Método: Trata-se de uma Revisão Integrativa da Literatura realizada nas bibliotecas e bases de dados: BVS, PubMed, Scielo e Portal de Periódicos CAPES. Foram arrolados dez estudos após a aplicação dos descritores não controlados: “consumidor/ consumer”, “acidente / acident” combinados pelo operador booleano “AND” e dos respectivos critérios de inclusão e exclusão. Resultados: A análise dos estudos selecionados possibilitou que três categorias emergissem: Principais fatores que levam a ocorrência de acidentes de consumo; Métodos de prevenção dos acidentes de consumo; e, O papel da equipe de saúde na prevenção dos acidentes de consumo. Conclusão: Nesse viés, compreende-se a importância da articulação para estratégias de prevenção de acidentes de consumo, sobretudo, no que se refere ao promissor papel da equipe de saúde neste âmbito, no que tange à educação para prevenção e avaliações para aperfeiçoamento dos produtos.
INVESTIGATION OF WIND ENERGY POTENTIAL OF FOUR DIFFERENT SITES OF LIBYA BY USING WEIBULL DISTRIBUTION
Authors: SELİMLİ Selcuk , SHTEWI Fauzi Ammar , FAHED Abdel Karim Amar , YAMAN KOYMATCIK Çagıl , ÖZKAYMAK Prof. Dr. Mehmet
Published: August 2021

Bu çalışmada, Libyanın Espiaa, Msallata, Alqatrun ve Adirsiyah bölgesinin rüzgâr enerjisi kapasitesi Weibull dağılımı ile değerlendirilmiştir. Justus'un Ampirik Yöntemi (EMJ), Grafik Yöntemi (GM) ve Maksimum Olabilirlik Yöntemi (MLM) olmak üzere üç farklı Weibull dağılımı yöntemi kullanılmıştır. Sonuç olarak, en iyi hız tahmin performansı grafiksel ve maksimum olabilirlik yöntemleri ile elde edilmiştir. Güç yoğunluğu tahminlemesine göre Msallata'nın rüzgâr gücü potansiyelinin 60 m yükseklikte 444.743 W/m² güç yoğunluğu ile en iyi olduğu ve Espiaa'da ise 414.98 W/m² potansiyel ile ikinci sırada olduğunu görülmüştür. Alqatrun 184.134 W/m² güç yoğunluğu ile üçüncü sırada, sonuncu sırada ise 101.201 W / m² potansiyeli ile Adirsiyah belirlenmiştir. 20 m yükseklik için Msallata'nın güç yoğunluğu 418.502 W/m², Espiaa'da 414.873 W/m², Alqatrun'da 137.736 W/m² ve Adirsiyah'da 77.993 W/m² olarak belirlenmiştir. Maksimum güç potansiyeli Msallata'da, minimum ise Adirsiyah'da belirlenmiştir. Gerçek sonuçlara en yakın değerler sağlayan en uygun istatistiksel yöntemi belirlemek için varyans (R²), kök ortalama kare hata (RMSE), ortalama sistematik hata (MBE) ve ortalama mutlak hata (MAE) değerleri hesaplanmış ve değerlendirilmiştir. Adirsiyah'ta 20 m yükseklik için en iyi sonuçlar GM yöntemi ile elde edilmiştir. Bu durum hesaplanan 0.9948 maksimum R² ve minimum 0.0245, 0.00037 RMSE ve MAE değerleri ile değerlendirilmiştir. Alqatrun'da MLM yöntemi 0.9899 R², 0.0335 RMSE, 0.00049 MAE ile en uygun yöntem olarak ve en düşük karşılaştırma değeri olan 1.7e-5 MBE ile belirlenmiştir. Espiaa için GM yöntemi 0.9984 R², 0.0186 RMSE, 1.23e-06 MBE ve 0.00033 MAE değerleri ile en uygun yöntem olarak belirlendi. Msallata için EMJ yöntemi 0.9985 R², 0.0146 RMSE, 2,4e- 07 MBE ve 0.00022 MAE değerleri ile en iyi yöntem olarak belirlendi.60 m yükseklik için Adirsiyah'ta EMJ yöntemi 0,9957 R², 0.0221 RMSE ve 0,00027 MAE değerleri ile en uyumlu sonuçları vermiştir. Alqatrun'da MLM yöntemi 0,9979 R², 0,0151 RMSE, 2,63e-06 MBE ve 0.00024 MAE değeri ile en yakın sonuçları sağlamıştır. Espiaa için MLM yöntemi 0,9988 R², 0,0163 RMSE, 1,21e-06 MBE ve 0,00029 MAE değeri ile en uygun yöntem olarak belirlenmiştir. Msallata için EMJ yöntemi 0,9986 R², 0,0163 RMSE, 1,83e-07 MBE ve 0,00019 MAE ile en uygun yöntem olarak belirlenmiştir.