bluuebunny/crossref_metadata_2025 huggingface dataset:
ВПЛИВ НАХИЛУ ФАСАДУ НА ПРОЦЕСИ ПОШИРЕННЯ ПОЖЕЖІ ЗОВНІШНІМИ ОГОРОДЖУВАЛЬНИМИ КОНСТРУКЦІЯМИ
Authors: Балло Ярослав
Published: August 2023

На основі результатів експериментальних досліджень з оцінювання поширення пожежі зовнішніми вертикальними конструкціями будівель визначено характер змін температурних розподілів на поверхні досліджуваного фрагмента фасаду залежно від значення його нахилу. Здійснено аналіз проблемних аспектів під час проведення оцінювання поширення пожежі зовнішніми огороджувальними конструкціями складної форми та обґрунтовано актуальність проведених експериментальних натурних досліджень. Наведено етапи організації експерименту, підготовки випробувальної установки та обладнання вимірювальної техніки під час проведення імітаційних випробувань на базі пожежно-випробувального полігону. Описано характер поширення полум’я досліджуваним фрагментом фасадної системи для кожного етапу досліджень. На основі отриманих даних щодо температурного режиму на поверхні досліджуваного фрагмента фасаду побудовано графіки температурних залежностей в часі щодо кожного етапу експериментальних досліджень, а також відповідні поліноміальні регресійні залежності. Здійснено аналіз можливості поширення пожежі зовнішніми вертикальними огороджувальними конструкціями на вище розташовані поверхи на основі міжнародних критеріїв та особливостей конструктивного виконання фасадних систем. Порівняння отриманих закономірностей дало змогу зробити висновки щодо впливу нахилу фасаду під різними кутами на процеси поширення пожежі зовнішніми огороджувальними конструкціями, а також визначити подальші напрями досліджень щодо забезпечення якісного оцінювання процесів поширення пожежі фасадами будівель. Отримані результати можуть бути передумовою для зміни підходів щодо оцінювання процесів поширення пожежі зовнішніми вертикальними огороджувальними конструкціями, в яких на сьогодні не враховуються такі конструктивні характеристики фасадів, як кути їх можливого нахилу.
ПОРІВНЯЛЬНИЙ АНАЛІЗ ДІЯЛЬНОСТІ ГАЗОДИМОЗАХИСНИКІВ РІЗНИХ ВІКОВИХ ГРУП
Authors: Скоробагатько Тарас , Єременко Сергій , Пруський Андрій , Савельєв Ігор , Стрілець Віктор , Сидоренко Володимир
Published: August 2023

З огляду на проведений аналіз важливою та невирішеною частиною проблеми підвищення ефективності ліквідації надзвичайних ситуацій, пов’язаних з оперативною діяльністю пожежників-рятувальників у непридатному для дихання середовищі, є брак відомостей щодо того, як вік газодимозахисника впливає на показники, зокрема фізіологічні, які характеризують результати виконання професійно-важливих завдань. Проведено порівняльні експериментальні дослідження результатів діяльності газодимозахисників двох вікових груп в апаратах на стисненому повітрі (АСП) на мобільному тренажері контейнерного типу виробництва компанії MAW GmbH (мобільний тренажер), який найбільш повно відтворює умови роботи рятувальників у непридатному для дихання середовищі, з їх подальшим статистичним аналізом. Статистичний аналіз отриманих даних здійснено з рівнем значущості a=0,05. Визначено, що для газодимозахисників усіх вікових груп сам процес включення в АСП та очікування роботи в екстремальних умовах є значущим стрес-фактором для особового складу всіх вікових груп. Запропоновано відповідні практичні рекомендації, зокрема: під час проведення газодимозахисниками практичних занять в апаратах на стисненому повітрі особливу увагу варто звертати на пожежників-рятувальників старшої вікової групи, у яких частота серцевих скорочень (ЧСС) починає перевищувати 150 уд./хв, для молодшої вікової групи такого контролю потребує особовий склад, у якого ЧСС починає перевищувати 165 уд./хв; у процесі оперативного контролю та планування діяльності газодимозахисників на посту безпеки доцільно враховувати, що час виконання оперативного завдання в непридатному для дихання середовищі у особового складу старшої вікової групи може бути більшим на 15–20%; на посту безпеки під час попередніх розрахунків часу роботи в АСП для газодимозахисників усіх вікових груп доцільно використовувати показник легеневої вентиляції wл » 80 л/хв; на посту безпеки доцільно використовувати спрощені розрахунки часу роботи в АСП. Так, у разі роботи в АСП з об’ємом балона 8 л загалом можна використовувати показник швидкості падіння тиску, також на посту безпеки доцільно планувати діяльність ланок ГДЗС таким чином, щоб вони змінювались, якщо є необхідність у довготривалому проведенні аварійно-рятувальних робіт, через 15–20 хвилин.
ЕКСПЕРИМЕНТАЛЬНІ ДОСЛІДЖЕННЯ ЩОДО ЗАСТОСУВАННЯ ГОРИЗОНТАЛЬНИХ ЗРОШУВАЧІВ ДЛЯ ПРОТИПОЖЕЖНИХ ВОДЯНИХ ЗАВІС
Authors: Бенедюк Вадим , Стилик Ігор , Тимошенко Олексій , Онищук Андрій , Маладика Лариса
Published: August 2023

Анотація. Наведено результати аналізу публікацій щодо досліджень водяних завіс. Попередньо було визначено, що відомі горизонтальні зрошувачі, які призначені, перш за все, для стандартного горизонтального настінного монтажу для гасіння пожеж по площі підлоги, при нестандартному вертикальному положенні, розеткою вниз, можуть бути використані для створення водяних завіс. Але аналіз технічних характеристик зрошувачів такого типу, від різних виробників, показав, що наведені паспортні дані щодо розподілу води зі зрошувачів, навіть для горизонтального положення, мають наближені, орієнтовні траєкторії потоків та моделі зрошування. Для вертикальної орієнтації цих зрошувачів такі дані взагалі відсутні. У ДСТУ EN 12259-1:2019 передбачена методика випробувань горизонтальних зрошувачів на розподіл води по площі підлоги та змочування стін тільки для їхнього горизонтального положення. Тому експериментальні дослідження наведених зрошувачів для водяних завіс виконувались по розробленій робочій методиці випробувань, на прикладі, одиночного горизонтального спринклера, яка передбачає визначення такої його орієнтації (горизонтальної чи вертикальної), за якої досягається найбільш ефективний захист від пожежі віконного прорізу заданого розміру. Критеріями оцінки були: отримані величини інтенсивності розподілу води по горизонтальній площі, розміри цієї площі та її межі відносно зрошувача та вікна. За результатами проведених досліджень були визначені інтенсивності розподілу води по горизонтальній поверхні та побудовані 3D моделі інтенсивності розпилу води зі зрошувача відносно його розташування до вікна. Дослідження показали, що найбільш ефективний захист віконного прорізу може бути досягнутий при нестандартній - вертикальній орієнтації зрошувача. Тобто, підтверджена можливість більш ефективного застосування зрошувачів указаного типу для створення водяних завіс. Але зазначене потребує подальших досліджень, зокрема, з визначення та оцінки фактичної екранувальної здатності такої завіси від проникнення небезпечних факторів пожежі, зокрема, теплового потоку.
Menjaga kepastian dan perlindungan kepemilikan tanah masyarakat
Authors: Junarto Rohmat , Mujiati Mujiati , Juliyani Agelliyah
Published: August 2023

Pengelolaan lahan (aset tanah) secara fisik, administratif dan yuridis mampu memberikan kemanfaatan bagi pemiliknya secara ekonomi dan sosial. Sebaliknya, penelantaran aset tanah menghambat tujuan program pembangunan, kedaulatan pangan, ketahanan ekonomi serta terganggunya harmoni sosial. Makalah ini bertujuan untuk menyajikan temuan studi tentang pentingnya kegiatan pengabdian masyarakat dengan tema sosialisasi dan supervisi gerakan pemasangan patok batas bidang tanah di Dusun Kemesu dan Gegerbajing, Desa Pagerharjo Kecamatan Samigaluh Kabupaten Kulonprogo. Gerakan tersebut menjadi salah satu upaya bersama untuk mencegah penelantaran aset tanah masyarakat. Kami menggunakan metode participatory action research dengan beberapa forum seperti: focus group discussion dan wawancara. Kemudian, kami menuliskannya kembali secara deskriptif berdasarkan data-data yang telah terkumpul pada saat kegiatan pengabdian berlangsung agar jelas dan runtut. Temuan studi menunjukkan bahwa sosialisasi dan supervisi gerakan pemasangan patok batas bidang tanah mampu menggerakkan masyarakat untuk sadar dan tertib di bidang pertanahan. Penelantaran tanah pun terhindarkan karena terdapat pengelolaan aset tanah dalam bentuk pemasangan batas bidang tanah secara permanen, mengadministrasikan nama pemilik tanah atau kuasanya yang terkini serta membuat berita acara kesepakatan pemasangan tanda batas tanah. Pada akhirnya, kesiapan masyarakat dalam mengelola kepemilikan atas aset tanah mampu mempermudah terselenggaranya pendaftaran tanah sistematis lengkap.
Pengembangan desain logo dan kemasan untuk meningkatkan daya saing usaha kecil menengah
Authors: Khalifaturofi'ah Sholikha Oktavi , Ayu Sekarsari Larasati , Hiqmah Faizatul , Adi Suminto Miftahul , Delonix Renzina Yudha , Ulum Achmad Saiful
Published: August 2023

Kegiatan pengabdian masyarakat ini dilakukan pada UKM Bluder Aisha 99. UKM ini telah berdiri sejak tahun 2000an. Awal mulanya UKM ini memproduksi beberapa jenis kue dan akhirnya mulai fokus ke bluder. Sejak fokus di usaha bluder, mitra menghadapi beberapa kendala. Diantaranya adalah kue bluder belum banyak dikenal oleh masyarakat sehingga banyak kue bluder yang kembali akibat tidak terjual. Selain itu, saluran pemasaran yang dilakukan UKM hanya berkisar ke pemasaran tradisional dan belum merambah ke digital marketing. Kegiatan pengabdian ini bertujuan untuk mengembangkan desain logo dan kemasan untuk meningkatkan daya saing UKM bluder Aisha 99. Metode yang dilakukan adalah dengan participatory learning and action (PLA) yang memiliki ciri-ciri sosialisasi, diskusi, dan praktik secara langsung. Hasil pengabdian masyarakat adalah pendekatan PLA ini berlangsung dengan baik. Dari pengabdan ini diperoleh desain stiker, kartu nama digital untuk whatsapp bisnis, dan banner yang menarik sebagai salah satu solusi respon pasar yang kurang. Hasil yang mitra rasakan adalah terdapat peningkatan dalam hal pesanan kue bluder dan respon pasar terhadap kue bluder membaik. Dapat disimpulkan bahwa desain logo dan kemasan berpengaruh terhadap daya beli konsumen.
Penerapan sistem jaminan produk halal pada UMKM untuk meningkatkan daya saing produk
Authors: Munawar M. Soleh Al , Rohmah Miftakhur , Anton Rahmadi  , Marwati  , Rachmawati Maulida
Published: August 2023

Usaha Mikro Kecil dan Menengah (UMKM) adalah salah satu usaha untuk yang cukup populer di masyarakat Indonesia. Salah satu usaha yang berkembang pesat di Indonesia adalah usaha dibidang pangan.  Namun demikian, dalam perkembangannya terdapat kendala untuk meningkatkan daya saing produk UMKM, yaitu tidak dimilikinya sertifikat halal. Di Indonesia, kewajiban sertifikasi halal diatur dalam Undang-Undang Nomor 33 Tahun 2014 terkait jaminan kehalalan produk, khususnya produk yang masuk, beredar dan diperdagangkan di wilayah Indonesia harus bersertifikat halal. Pengabdian kepada masyarakat ini bertujuan melakukan pendampingan penyiapan persyaratan dan implementasi pemenuhan dokumen Sistem Jaminan Produk Halal (SJPH) terhadap UMKM Koperasi Kukar Idaman Lestari untuk memperoleh sertifikat halal melalui sosialisasi dan pendampingan sertifikasi halal agar produk yang dihasilkan terjamin kualitasnya dan dapat membantu melihat potensi usaha agar unggul dalam persaingan. Metode yang digunakan dalam kegitan ini adalah PAR (Participatory Action Research) dengan melibatkan partisipasi dan kolaborasi aktif antara pengabdi dan masyarakat atau pihak lain yang meliputi beberapa tahapan yaitu: (1) observasi dan wawancara; (2) identifikasi gap; (3) sosialisasi kepada UMKM; dan (4) penyiapan dokumen persyaratan dan pendaftaran sertifikat halal kategori self declare. Hasil pendampingan pelaku UMKM telah mengetahui pentingnya menghasilkan produk halal dan melakukan implementasi SJPH sehingga telah mendapatkan Sertifikat Halal melalui self declare sebagai pengakuan kehalalan produk. Manual SJPH yang dihasilkan dapat dijadikan pedoman untuk menerapkan sistem jaminan halal secara konsisten dari kegiatan yang telah dilaksanakan sehingga jika ditemukan ketidaksesuaian pelaku usaha akan melakukan tindakan perbaikan.
Implementasi sistem monitoring kebisingan berbasis web di pelabuhan terminal peti kemas
Authors: Subekti Arief , Santoso Mochamad Yusuf , Arninputranto Wibowo , Khairansyah Mades Darul , Khumaidi Agus
Published: August 2023

Salah satu misi Program Studi Teknik Keselamatan dan Kesehatan Kerja (K3) Politeknik Perkapalan Negeri Surabaya adalah melaksanakan kegiatan kemasyarakatan secara aktif dan produktif untuk mengembangkan Teknologi Keselamatan dan Kesehatan Kerja bidang industri umum maupun maritim. Pada kegiatan pengabidan masyarakat ini, kerjasama dilakukan dengan Pelabuhan Terminal Teluk Lamong untuk menyelesaikan permasalahan pemantauan kebisingan di pelabuhan. Menurut peraturan ketenagakerjaan, perusahaan wajib melakukan pemantauan lingkungan kerja, salah satunya kebisingan. Namun, pelabuhan tersebut memiliki area yang luas sedadngkan sumber daya K3 yang ada masih terbatas. Sehingga, aktivitas monitoring kebisingan belum dilakukan secara maksimal. Dari permasalahan tersebut, diusulkan solusi berupa perancangan dan implementasi Sistem Monitoring Kebisingan Lingkungan Kerja Berbasis Web. Kegiatan diawali dengan diskusi permasalahan mitra yang dilanjutkan ke tahap perancangan sistem. Perancangan dilakukan untuk perangkat keras dan perangkat lunak berbasis web. Sistem yang telah dirancang kemudian dipasang pada area dermaga pelabuhan peti kemas yang dilanjutkan dengan tahap monitoring dan evaluasi. Hasil pengujian pengukuran kebisingan menunjukkan bahwa alat yang dipasang pada area dermaga mampu memberikan pengukuran dengan tingkat presisi sebesar 91,59%. Sistem pengukuran kebisingan yang dirancang dapat menampilkan grafik pengukuran yang bisa dipantau melalui peramban desktop maupun mobile. Laman web mampu menampilkan grafik pengukuran secara real-time dengan sampling rate yang dapat disesuaikan oleh pengguna.
Peningkatan motivasi dan manajemen sumber daya manusia menuju kualitas kinerja perusahaan
Authors: Devi Nourma Ulva Kumala , Septiandika Verto , Tantri Revanggi Ayu
Published: August 2023

Kualitas SDM penting sebagai modal dasar perusahaan dalam pencapaian tujuan. Keberhasilan perusahaan tidak terlepas dari kerjasama seluruh pegawai baik pemimpin dan bawahan. Pemimpin yang tidak menjalin hubungan komunikasi yang harmonis dengan pegawai akan berpengaruh kepada kinerja yang diberikan. Kinerja dapat diartikan sebagai hasil kerja secara kuantitas dan kualitas yang diperoleh karyawan melalui penyelesaian tugas yang diberikan dengan rasa tanggung jawab dan sungguh-sungguh. Kinerja yang baik akan diperoleh apabila SDM mempunyai motivasi kerja yang tinggi. Motivasi mendorong karyawan untuk bertindak. Perlu dilakukan usaha-usaha untuk meningkatkan kinerja dan motivasi agar tujuan perusahaan dapat tercapai. Salah satu usaha yang dapat dilakukan adalah dengan kegiatan gathering dan pemberian motivasi. Kegiatan ini menggunakan metode ABCD (Asset-Based Community Development) dengan lima tahapan yaitu menemukan (discovery), impian (dream), merancang (design), menentukan (define) dan melakukan (destiny). Setelah diadakan kegiatan tersebut persentase karyawan tidak masuk menurun dari 59% ke 33%. Persentase pencapaian target oleh karyawan meningkat dari 48% menjadi 72%. Persentase prestasi yang dicapai oleh karyawan meningkat dari 29% menjadi 50%. Dan tingkat keyakinan karyawan untuk menyelesaikan masalah meningkat dari 61% ke 84%. Dari kegiatan tersebut karyawan memiliki motivasi untuk meningkatkan kinerja sehingga berdampak pada perusahaan. Melalui kegiatan tersebut diharapkan seluruh karyawan memiliki motivasi yang tinggi sehingga dapat meningkatkan kinerja yang diberikan.
PENGARUH CORPORATE GOVERNANCE TERHADAP VALUE OF THE FIRM DENGAN COST OF CAPITAL SEBAGAI VARIABEL INTERVENING
Authors: Gunawan Anita Jessica
Published: August 2023

Penelitian ini bertujuan untuk membuktikan pengaruh variabel-variabel corporate governance terhadap value of the firm. Variabel-variabel tersebut adalah ukuran dewan komisaris, ukuran dewan direksi, dan komisaris independen. Penelitian ini juga dilakukan untuk mengetahui pengaruh langsung maupun tidak langsung dari variabel cost of capital sebagai variabel mediasi dalam penelitian ini. Sampel yang digunakan dalam penelitian ini adalah perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia periode tahun 2017—2021. Sampel yang diperoleh dalam penelitian ini sebanyak 213 perusahaan. Jenis data yang digunakan dalam penelitian ini adalah data sekunder berupa laporan keuangan perusahaan yang dipublikasikan oleh Bursa Efek Indonesia. Teknik pengumpulan pada penelitian ini dilakukan dengan teknik dokumentasi yang diperoleh dari laporan keuangan perusahaan yang dipublikasikan. Teknik analisis data penelitian ini menggunakan Partial Least Squares Structural Equation Modeling (PLS-SEM) dengan basis analisis regresi. Alat analisis data yang digunakan adalah SmartPLS 4.0. Hasil penelitian ini menunjukkan bahwa variabel komisaris independen berpengaruh positif terhadap nilai perusahaan, sedangkan variabel ukuran dewan komisaris dan ukuran dewan direksi tidak berpengaruh. Variabel biaya modal berpengaruh positif terhadap nilai perusahaan. Di sisi lain, variabel ukuran dewan komisaris, ukuran dewan direksi, dan komisaris independen tidak berpengaruh terhadap biaya modal. Demikian pula, variabel biaya modal tidak memberikan pengaruh efek mediasi terhadap hubungan antara corporate governance terhadap value of the firm.
PEMEDIASIAN ANTARA PENGARUH E-WOM TERHADAP REPURCHASE INTENTION DENGAN MEDIASI BRAND IMAGE PADA PRODUK SKINCARE MEREK LOKAL INDONESIA YANG ADA DI E-COMMERCE
Authors: Putri Meilisa Regina , Sienarta Krismi Budi
Published: August 2023

Industri kecantikan di Indonesia mengalami pertumbuhan pesat sejak awal tahun 2020 karena tingginya permintaan masyarakat terhadap produk kecantikan. Produk skincare dengan merek lokal banyak bermunculan. Produk skincare mere lokal tersebut berlomba-lomba membangun citra positif melalui media sosial agar ulasan-ulasan positif bermunculan dari para pengguna produk skincare tersebut. Ulasan positif dari berbagai kanal e-commerce diharapkan menimbulkan minat beli yang berulang. Tujuan dari penelitian ini adalah untuk meneliti pengaruh Electronic Word-of-Mouth (E-WOM) terhadap niat pembelian dan dampaknya terhadap citra merek produk skincare lokal Indoensia. Dengan mengkaji hubungan antara E-WOM dan niat pembelian, penelitian ini bertujuan untuk mengetahui bagaimana rekomendasi dan diskusi online mempengaruhi kecenderungan konsumen untuk membeli produk. Penelitian ini dilakukan dengan menggunakan pendekatan penelitian kuantitatif. Populasi dalam penelitian ini adalah seluruh masyarakat yang menggunakan aplikasi e-commerce seperti shopee atau tokopedia dalam membeli produk. Sebanyak 90 orang responden diambil sebagai sampel untuk penelitian ini. Teknik pengambilan sampel yang digunakan adalah non probability purposive sampling, di mana responden dipilih secara sengaja berdasarkan kriteria tertentu yang relevan dengan penelitian. Data yang diperoleh dari responden kemudian dianalisis menggunakan teknik Partial Least Square (PLS) Hasil penelitian ini menunjukkan bahwa brand image memiliki pengaruh signifikan terhadap purchase intention. Ulasan konsumen di internet memainkan peran penting dalam membentuk citra merek, meskipun tidak memiliki pengaruh yang signifikan terhadap minat pembelian konsumen.

 

Kata kunci: E-WOM, minat pembelian kembali, Citra Merek
Plasticity of neural networks
Authors:   , Vink Jord Jan-Teunis
Published: August 2023

Despite improvements in acute stroke therapies and rehabilitation strategies, many stroke patients are left with long-term upper limb motor impairment, making stroke the leading cause of adult disability. Repetitive transcranial magnetic stimulation (rTMS) is a promising treatment for the promotion of upper limb recovery after stroke. rTMS is a non-invasive brain stimulation method that can modulate brain activity through electromagnetic induction. Before rTMS treatment can be applied in clinical rehabilitation programs, its long-term clinical efficacy needs to be evaluated, its working mechanism needs to be better understood, and patient selection criteria need to be defined.
The first chapters of this thesis describe fundamental research on how TMS can be used to modulate brain networks to target them therapeutically. The second part of this thesis focuses on the development of rTMS therapy for upper limb recovery after stroke. We show that rTMS treatment promotes upper limb recovery after stroke, reduces disability and dependence, and shortens the length of stay in a phase 2 randomized controlled trial in sixty stroke patients. We identified two potential treatment mechanisms that operate independently: normalization of motor cortex physiology and reorganization of the motor area in the affected brain hemisphere. Finally, we found that treatment efficacy is associated with residual motor function and intact corticospinal tract integrity. Therefore, selecting patients for rTMS treatment based on residual motor function or CST integrity may improve upper limb outcome. These results form the basis for a phase-3 multi-center clinical trial on the efficacy of rTMS treatment for the promotion of upper limb recovery after stroke.
Electrostatic manipulation of colloidal clusters
Authors:   , Rogier Faranaaz
Published: August 2023

In this thesis, we show that external electric fields can be used to manipulate clusters of colloidal particles. A cluster of particles can be expanded in a controlled fashion, can be arranged in a ring, and can have a negative Poisson’s ratio if there is significant anisotropy in the particle interactions.

The induced electric forces on the particles depend on the electric field and can be determined experimentally by the particle position. An electric field induces an electric dipole moment in metallic and dielectric media if there is a difference in dielectric constant between an object and its surrounding. It is shown that the induced electric dipole moment can be used in various ways to manipulate colloidal particles.

In this thesis, two set-ups are discussed to manipulate colloid clusters with an induced electric force. In the first set-up, the particles are adsorbed on a curved water-oil interface in an electric device. While the curved interface promotes particle movement towards the lowest position on the interface, the electrically induced forces act against the movement in this direction. This provides a method to control the position of the particles.
In the second part of this thesis, the particles contain a permanent magnetic dipole moment, which causes the particles to cluster into a rhombic-like structure. An induced electric dipole moment causes repulsion between particles, this breaks up the rhombic-like structure and causes the cluster to expand. When considering the cluster as a material, this material has a negative Poisson’s ratio.
ANALISIS DAMPAK DAYA TARIK WISATA MENGGUNAKAN PARTIAL LEAST SQUARE STRUCTURAL EQUATION MODELING (PLS-SEM)
Authors: Zazilah Auda Nuril , Hidayati Sri , Isnaeni Fajar
Published: August 2023

This study aims to analyze the impact of the tourist attraction of Oling River Food Banyuwangi on the social, economic and environmental fields. By using Partial Least Square – Structural Equation Modeling (PLS-SEM) which is based on the Ordinary Least Square (OLS) method, it is found that tourist attraction to the economy has a significant positive effect with a path coefficient of 0.75, a positive effect on the environment and a significant effect with a path coefficient of 0.67 , as well as a positive and significant social effect with a path coefficient of 0.832. The tourist attraction variable is significantly influenced by the environment, social, economy by 69.2%. This means that if the tourist attraction of oling river food is getting better and growing, the community's economy will increase, the environment will be better maintained and the social relations of the surrounding community will get better.
Analisis Regresi Faktor-Faktor Yang Mempengaruhi Hasil Produksi Padi Di Indonesia Bagian Barat
Authors: Loban Jeni Marianti
Published: August 2023

This study aims to measure the influence of factors affecting rice production in the western part of Indonesia. Data analysis used multiple linear regression analysis, using the independent variable X1 = land area (Ha), X2 = rainfall (mm) and X3 = rainy days (days) on the dependent variable, namely the amount of rice production (Y). In this study, it was analyzed how much influence the land area (Ha), rainfall (mm), rainy days (days) had on the amount of rice production (tons). Data analysis using the help of RStudio software. The regression model obtained is Y=61.6+0.000007917X_1-0.1541X_2+0.0002555X_3 with a value of R2=0.9268.
PENGEMBANGAN BAHAN AJAR UNTUK MENUNJANG PEMBELAJARAN KURIKULUM MERDEKA PADA MATERI BENTUK MOLEKUL FASE F SMA/MA
Authors: Farras Aulia Sugria  , Mawardi Mawardi , Isnaeni Fajar
Published: August 2023

After the pandemic, the Ministry of Culture, Research and Technology issued a solution to overcome learning lag, namely the implementation of an Merdeka Curriculum. In its implementation, the current Merdeka Curriculum still has obstacles regarding the availability of incomplete teaching materials, especially in Phase F chemistry learning. This study aims to develop and determine the level of validity of teaching materials on molecular shapes so that they can support the Merdeka Curriculum in Phase F chemistry learning SMA / MA. Teaching materials were developed based on the Plomp model developed by Tjeerd Plomp. There are 3 stages, namely initial investigation, prototype development, and assessment. Data were collected through primary data derived from the results of interviews, validity, and practicality. The results of individual interviews with students show that teaching materials have attracted the attention of students, the results of validity derived from 5 UNP chemistry lecturers obtained a score v = 0.82 with a valid category, while the results of practicality derived from 2 teachers of SMAN 2 Padang obtained a score NP = 88% and and 9 students obtained a score NP = 95% so that both are categorized as very practical. Based on this, this teaching material is suitable for use to support the Merdeka Curriculum. Teaching materials are expected to be a solution for teachers in carrying out chemistry learning in accordance with the Merdeka Curriculum to create students who have critical thinking, careness and complex problem solving skills.
Focal Onset Seizures: New Treatment Options in The Clinical Practice
Authors: Steinhoff Bernhard J. , Carreño Mar , Taylor Jennifer
Published: August 2023

This symposium took place during the 2023 Congress of the European Academy of Neurology (EAN). Mar Carreño, Director, Epilepsy Unit, Hospital Clínic and Instituto Clavel, Barcelona, Spain, presented the definition of drug-resistant epilepsy (DRE), and stressed that uncontrolled epilepsy does not necessarily indicate DRE. Before a diagnosis of DRE is made in a patient not responding to medication, questions should be asked regarding the initial epilepsy diagnosis. Carreño discussed paroxysmal events that may mimic epilepsy, and presented three cases of misdiagnosed DRE that were subsequently correctly identified as cardiac syncope, a psychogenic event, and use of inappropriate medication in a patient with generalised epilepsy. The second part of Carreño’s presentation focused on patients with confirmed DRE. They outlined the complications of DRE, including sudden unexpected death in epilepsy (SUDEP), which should be discussed with the patient. Carreño finished their lecture with a discussion of comorbid conditions, including neuropsychiatric comorbidities, which affect one in three patients with epilepsy. Bernhard J. Steinhoff, Medical Director, Kork Epilepsy Center, Kehl, Germany, then discussed the clinical approach to patients with DRE, including treatment options, the range of anti-seizure medications (ASM), and the reasons for failure of first-line treatment, noting that the probability of achieving seizure freedom decreases with each failed ASM. Steinhoff explored the options of substitution monotherapy or combination therapy after failure of the first ASM, before describing cenobamate (CNB) add-on therapy. A randomised, placebo-controlled, dose-response trial showed that adjunctive CNB reduced focal (partial)-onset seizure frequency in a dose-related fashion. Several papers have been published providing real-world evidence to show that adjunctive CNB therapy is associated with improved seizure outcomes, and that the number of concomitant ASMs could be reduced. The symposium concluded with a question and answer session.
Mitochondrial DNA Maintenance Disorders: Impact of Impaired Deoxynucleoside Triphosphates Metabolism
Authors: Martí Ramon , Boyes Bronwyn
Published: August 2023

The maintenance of mitochondrial DNA (mtDNA) is dependent upon several nuclear gene-encoded proteins including enzymes forming the replisome needed to synthesise mtDNA. These enzymes need to be present in balanced quantities to function properly. In addition, mtDNA synthesis requires a balanced supply of nucleotides that is achieved by nucleoside recycling inside the mitochondria, and nucleotide import from the cytosol. Mitochondrial DNA maintenance defects are a group of diseases caused by pathogenic variants in the nuclear genes involved in mtDNA maintenance, and result from impaired mtDNA replication. Pathogenic nuclear gene variants identified to date include genes that encode enzymes of mtDNA replication machinery (such as POLG), genes that encode proteins that help to maintain a balanced mitochondrial nucleotide pool (such as TK2), and genes that encode proteins involved in mitochondrial fusion. Here, the presentation provided by Ramon Martí, Research Group on Neuromuscular and Mitochondrial Diseases, Vall d’Hebron Institut de Recerca, Barcelona, Spain, and CIBERER, Madrid, Spain, is summarised. A leading expert on mitochondrial pathology, Martí presented at the Euromit 2023 International Conference on Mitochondrial Disease, which took place in Bologna, Italy, in May 2023.
Study for Assessment of Mental Health in Survivors of COVID-19
Authors: Meena Priyanka , Deopujari Kuldeep , Agrawal J.P. , Dube Simmi
Published: August 2023

Background: The authors aimed to study the levels of anxiety, depression, and stress in survivors of COVID-19, and to correlate their level with severity of COVID-19 infection.

Methodology: This study was conducted on a total of 200 survivors of COVID-19 as an observational cross-sectional study. The cohort reported to the Hamidia Hospital, Bhopal, India, during the study period of 21 months. The Depression Anxiety Stress Scale-21 (DASS21) was used for assessment of mental health.

Results: Overall, depression, anxiety, and stress were observed in 38.5% of cases, 38.5% of cases, and 11.0% of cases, respectively. The authors reported a significant association of worst saturation recorded with depression and severity of depression (p<0.05); significant association of depression and severity, and anxiety and its severity; and severity of stress with moderate-to-severe high-resolution CT findings (p<0.05). The authors also documented a medium positive and significant correlation of the severity of COVID-19 infection with stress and DASS21 overall score (analysis of variance: r=>0.40; p<0.05). However, a weak positive but significant correlation of severity with depression and anxiety was noted (r=0.20–0.40; p<0.05). The authors reported a weak positive correlation of worst saturation with depression and anxiety, as well as overall DASS21 score (r=0.20–0.40; p<0.05).

Conclusion: COVID-19 has long-term effects, especially in the form of psychological morbidity. Patients have recovered from the physical illness, but psychological distress and mental problems are still persistent among the survivors as the prevalence of depression, anxiety, and stress is reported to be high among them.
Defining Meaningful Outcomes for Patients with Spinal Muscular Atrophy in the Era of Gene Therapy
Authors: Haberlová Jana , Muntoni Francesco , Mercuri Eugenio , Roberts Eleanor
Published: August 2023

Spinal muscular atrophy (SMA) occurs due to a mutation in the SMN1 gene. It most typically has an onset in early childhood and presents as impairment in motor, bulbar, and respiratory function. In a symposium at the European Paediatric Neurology Society’s (EPNS) 2023 congress, three leading experts in SMA discussed the findings of real-world evidence (RWE) studies of the first gene therapy approved in NMD, in 2019 in the USA, and 2020 in Europe. Onasemnogene abeparvovec combines an adeno-associated virus (AAV9) vector with a functional copy of SMN complementary DNA, and is delivered in a single infusion. While clinical trials of onasemnogene abeparvovec show its efficacy and safety in populations with SMA who are symptomatic and pre-symptomatic, RWE studies have expanded the understanding of this therapy to wider SMA patient groups in the real-world clinical practice setting. Combined, such studies show how administration of onasemnogene abeparvovec in patients with symptomatic SMA can lead to motor and respiratory function improvement or stabilisation and achievement of motor milestones in naïve or pre-treated patients, while in patients who are pre-symptomatic, administration may lead to a normal development. The experts also discussed how understanding the benefit/risk profile of this gene therapy can help with decision-making over its use in patients with SMA. They highlighted how onasemnogene abeparvovec efficacy and safety can be affected by clinical status, disease severity, weight, age, and previous treatment at the time of infusion. Recently published RWE points to improvements being best predicted by baseline Children’s Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP-INTEND) score and age at treatment initiation, and in regard to safety and tolerability profile, liver enzyme elevation is the most predominant treatment-emergent adverse event (TEAE) with onasemnogene abeparvovec; hence, a prednisolone (or equivalent) dosing regimen is administered prior to, during, and for at least 3 months following infusion. The experts discussed how careful monitoring and adequate multidisciplinary team discussion, including colleagues from other specialities, such as hepatologists and paediatric immunologists, is advised in all cases of SMA receiving an onasemnogene abeparvovec infusion.
Development of the Clinical Myotonia Rating Scale and a Mexiletine Prescribing and Monitoring Algorithm for Patients with Non-Dystrophic Myotonia
Authors: Vicart Savine , Roberts Eleanor
Published: August 2023

The two most common forms of non-dystrophic myotonia (NDM) are myotonia congenita (Thomsen disease or Becker-type) and paramyotonia congenita. Symptoms, including muscle stiffness, cramps, and transient weakness, can affect a person’s quality of life. An unmet need for a validated tool to assess myotonia symptom severity and frequency, as well as disability caused by myotonia, led to the development of the Clinical Myotonia Rating Scale (CMRS). At the 9th Congress of the European Academy of Neurology (EAN), Budapest, Hungary, 1st–4th July 2023, a poster was presented regarding validation and reliability testing of the CMRS, the results of which are discussed here. Such a tool is needed when first assessing myotonia symptoms in a patient with NDM, as well as when assessing their response to myotonia-targeting medication. One such drug is mexiletine, a Class 1B antiarrhythmic agent that is approved for the treatment of myotonia symptoms in adults with NDM. Although a number of studies, including clinical and real-world trials in people with NDM, have not found mexiletine to be associated with impaired cardiac function, but as an antiarrhythmic drug, cardiac assessment is required with mexiletine prescription. Also presented at the 2023 EAN meeting is an algorithm to aid prescribers in understanding patients in whom mexiletine may be contraindicated, tests needed prior to mexiletine prescribing, and cardiac monitoring under treatment in patients with NDM. This algorithm was developed utilising expert opinion, the mexiletine summary of product characteristics, and a literature review of mexiletine safety data in NDM.
Lymphoma of Nervous System or the Great Imitator in Neurology
Authors: Cholakova Maria , Mihnev Nikolay , Staikov Ivan
Published: August 2023

Background: Lymphoma of the central nervous system (CNS), both primary and secondary, represents a very rare part of patients with non-Hodgkin lymphoma.

Methods: Exams included a neurological exam, laboratory blood tests, МRI, biopsy, and electromyography.

Results: Three different clinical cases of patients with lymphoma of the nervous system are presented. The first patient is a 44-year-old male admitted to the emergency room because of neck stiffness, with MRI data for a tumour in the left cavernous sinus area. Biopsy was performed 3 months prior to hospitalisation, showing connective tissue, partially hyalinised. Lumbar tap was performed to exclude CNS infection. Cerebrospinal fluid (CSF) examination showed lymphocytic pleocytosis, atypical cells in different phases of mitosis, and the result did not confirm lymphocytic choriomeningitis. Flow cytometric measurement (FCM) of CSF led to the diagnosis of T-lymphoblastic lymphoma of CNS.

The second patient is a 50-year-old female hospitalised in the authors’ neurological department because of lower limb weakness and decreased sensation, dysphagia, and facial nerve palsy. Brain MRI showed no abnormal lesions. Guillain–Barré syndrome was considered after performing electromyography and electroneurography. CSF showed lymphocytic pleocytosis and 47% of them were atypical. FCM of CSF helped the authors diagnose the patient with B-lymphoblastic lymphoma.

The third case presents a 63-year-old male with right sided hemiparesis and progressive cognitive impairment. Previously performed CTs and MRIs of the brain showed both hemispheres and left cerebellar peduncle diffuse lesions. Ischaemic stroke, tumour, and CNS infectious disease were considered. Most of these were excluded because CSF showed no pathological findings. Brain tissue biopsy of one of the lesions was performed, and the patient was diagnosed with diffuse large B cell lymphoma.

Conclusion: Lymphoma of the CNS is rare disease. Differential diagnoses include different conditions. FCM of CSF and biopsy could be useful in complicated patients and unknown diagnosis affecting the CNS.
PENGARUH KEPEMILIKAN APLIKASI MOBILE BANKING DAN KONDISI EKONOMI ORANG TUA TERHADAP PERILAKU KONSUMTIF DI KALANGAN MAHASISWA FKIP UGJ CIREBON
Authors: Febianti Yopi Nisa , Umaroh Umaroh , Rusdiyana
Published: August 2023

This study aims to determine whether there is an effect of ownership ofapplications mobile banking and the economic condition of parents on consumptive behavior among students of FKIP UGJ Cirebon. The research methodology used is a quantitative approach with a survey method. The population of this study were all active FKIP students with a sample of 71 students. Sampling technique using Accidental Sampling. Data collection techniques using a questionnaire and then data processing using SPSS software version 25.0. Data analysis used multiple linear regression. The results showed that there was a significant effect of ownership ofapplications mobile banking on consumptive behavior among FKIP students, this evidenced by the t-value  of 7.677 which was greater than the t-table which was 1.99495 and the significance value of 0.000 was smaller than the error level of 0, 05. The economic condition of parents on consumptive behavior among FKIP students has a significant influence, this is evidenced by the t-value  of 7.090 which is greater than the t-table which is 1.99495 and the significance value of 0.000 is smaller than the error level of 0.005. Ownership ofapplications mobile banking and the economic conditions of parents have a significant effect on consumptive behavior among FKIP students, as evidenced by the coefficient of determination of 0.681 or 68.1% while the rest is influenced by other factors. Thus, ownership ofapplications mobile banking and the economic condition of parents have a positive effect on consumptive behavior among students of FKIP UGJ Cirebon.
DESAIN BAHAN AJAR BERORIENTASI PEMBELAJARAN BERBASIS MASALAH UNTUK MENINGKATKAN KEMAMPUAN MEMECAHKAN MASALAH
Authors: Indri Rochmatika
Published: August 2023

This study aims to determine the development of teaching materials oriented to problem-based learning models to improve problem-solving skills. To find out student responses to module teaching materials that are oriented to problem-based learning models. Knowing the increase in students' problem-solving skills after using module teaching materials in the learning process. The sample in the study was IPS class X students at SMAN 1 Tukdana, Indramayu Regency with a total of 24 students. This research is a product development research or Research and Development (R&D). The research design that the authors use is the ADDIE development model. The results of the feasibility test showed that the module teaching materials were suitable for use in the learning process by obtaining a percentage of 89%, including the very valid category. The results of student responses to the module teaching materials were good, with a percentage of 83.38%. The N-gain results of the use of teaching materials in the learning process can increase students' problem-solving abilities by 0.49, included in the medium category, the t-test results show t_count≥t_table or 13.482 ≥ 2.093 then Ha is accepted and Ho is rejected, thus the teaching material is oriented problem-based learning can improve the problem-solving skills of class X IPS SMA Negeri 1 Tukdana, Indramayu Regency.
Counter Effect of Trichoderma harzianum Rifai. Against Cr (VI)
Authors: Akhtar Sundus , Shafqat Ayesha , Sherazi Syeda Mariam , Aslam Sonia , Khalil Habiba , Shakir Rubina , Khan Muhammad Arslan
Published: August 2023

Industrial and sewage water ejection in river and streams on daily basis and wide use of heavy metal is contaminating our surroundings. Among all the valences, Cr (VI) is regarded as a hazardous ion, which contaminates groundwater and can be transferred through the food chain In-vitro study was carried out in laboratory in which impact of Cr (VI) on Trichoderma harzianum was studied. For those two experiments i.e., solid medium assay and liquid broth assay were conducted. In solid medium assay, the radial growth, morphological alterations (appearance of colony, changes in the morphologies of spores and hyphae) in T. harzianum and inhibition zone under the stress of Cr (VI) at different doses i.e., 0, 1000, 2000, 3000, 4000 and 5000 ppm were studied. The results showed that radial growth was insignificantly reduced at highest dose (5000 ppm) i.e., 3.3% as compared to control. Moreover, no inhibition zone formed, and the mycelial pattern of tested fungi was crossing the disc zones. However, at 5000 ppm of Cr (VI), about 0.2 mm of concentric zone was observed. While no phialides were observed at higher doses of Cr (VI). Furthermore, in liquid broth experiment, mycelial growth, and biochemical attributes [Total protein content (TPC), Peroxidase (POX) and Catalase (CAT) activities] were studied after 7 days of incubation. The results revealed that the fresh and dry weight of T. harzianum was increased up to -200% comparison to control. The level of TPC, POX AND CAT increased by -10 % to -94% with the increasing concentration of Cr (VI) i.e., 1000 to 5000 ppm. Thus, the findings showed that T. harzianum could be used as bioremidier against Cr (VI). Further in- situ studies need to be taken to eradicate the presence of heavy metals in the environment by using fungus for bioremediation purpose in future.
Ultra-shallow fluorine implantation from r.f. plasma as a method for improvement of electro-physical properties of MIS structures with PECVD gate dielectric layers
Authors: Kalisz M. , Mroczynski R.
Published: August 2023

In this work a comprehensive analysis of changes in electrical and reliability parameters, which are introduced by the presence of a fluorine-rich layer in the gate structure based on MOS (Al/SiO2/Si) and MIS (Al/SiOxNy/Si) system, has been carried out. The surface of silicon substrates prior to the test structure execution was subjected to the processes of ultra-shallow ion implantation from CF4 plasma, different, than those usually found in the literature. To this end, the conventional plasma reactors were utilized to carry out a plasma enhanced chemical vapour deposition process PECVD and reactive ion etching RIE. To perform gate dielectric layers the PECVD method was used. The conducted analysis of the electrical properties was complemented by spectroscopic measurements (SIMS), which allowed the identification of causes and effects of observed changes in electro-physical parameters.
Plasma polymers used for controlled interphase in polymer composites
Authors: Cech Vladimir , Babik Adam , Knob Antonin , Palesch Erik
Published: August 2023

The performance of fiber-reinforced composites is strongly influenced by the functionality of composite interphases. Sizing, i.e. functional coating (interlayer), is therefore tailored to improve the transfer of stress from the polymer matrix to the fiber reinforcement by enhancing fiber wettability, adhesion, compatibility, etc. The world market is dominated by glass reinforcement in unsaturated polyester. However, commercially produced sizing (wet chemical process) is heterogeneous with respect to the thickness and uniformity, and hydrolytically unstable. Companies search for new ways of solving the above problems. One of the alternative technologies is plasma polymerization. Plasma polymer films of hexamethyldisiloxane, vinyltriethoxysilane, and tetravinylsilane, pure and in a mixture with oxygen gas, were engineered as compatible interlayers for the glass fiber/polyester composite. The interlayers of controlled physicochemical properties were tailored using the deposition conditions with regard to the elemental composition, chemical structure, and Young’s modulus in order to improve adhesion bonding at the interlayer/glass and polyester/interlayer interfaces and tune the cross-linking of the plasma polymer. The optimized interlayer enabled a 6.5-fold increase of the short-beam strength compared to the untreated fibers. The short-beam strength of GF/polyester composite with the plasma polymer interlayer was 32% higher than that with commercial sizing developed for fiber-reinforced composites with a polyester matrix. The progress in plasmachemical processing of composite reinforcements enabled us to release a new conception of composites without interfaces.
Linking cell cycle to hematopoietic stem cell fate decisions
Authors: Treichel Sydney , Filippi Marie-Dominique
Published: August 2023

Hematopoietic stem cells (HSCs) have the properties to self-renew and/or differentiate into any blood cell lineages. In order to balance the maintenance of the stem cell pool with supporting mature blood cell production, the fate decisions to self-renew or to commit to differentiation must be tightly controlled, as dysregulation of this process can lead to bone marrow failure or leukemogenesis. The contribution of the cell cycle to cell fate decisions has been well established in numerous types of stem cells, including pluripotent stem cells. Cell cycle length is an integral component of hematopoietic stem cell fate. Hematopoietic stem cells must remain quiescent to prevent premature replicative exhaustion. Yet, hematopoietic stem cells must be activated into cycle in order to produce daughter cells that will either retain stem cell properties or commit to differentiation. How the cell cycle contributes to hematopoietic stem cell fate decisions is emerging from recent studies. Hematopoietic stem cell functions can be stratified based on cell cycle kinetics and divisional history, suggesting a link between Hematopoietic stem cells activity and cell cycle length. Hematopoietic stem cell fate decisions are also regulated by asymmetric cell divisions and recent studies have implicated metabolic and organelle activity in regulating hematopoietic stem cell fate. In this review, we discuss the current understanding of the mechanisms underlying hematopoietic stem cell fate decisions and how they are linked to the cell cycle.