bluuebunny/crossref_metadata_2025 huggingface dataset:
Phenotypic Similarities Within The Morphologic Spectrum Of DICER1-Associated Sarcomas and Pleuropulmonary Blastoma -- Histopathologic Features Suggesting Genetic Testing and Counselling
Authors: Roy Paromita , Das Anirban , Singh Angad , Panda Joyshree , Bhattacharya Arpita , Gehani Anisha , Parihar Mayur , Sukumaran Reghu , Achari Rimpa , Alaggio Rita , Field Amanda , Hill Ashley , Dehner Louis , Schultz Kris Ann
Published: June 2021

Context - DICER1-associated sarcomas are rare. These are currently
described under a wide variety of appellations; morphologic
characterizations in reported cases and sites of occurrence have also
been disparate. Design – We aimed to review pediatric sarcomas
associated with DICER1-mutation reported at our center, along with
literature review, to identify histologic hallmarks for diagnosis.
Results - A 12 year old girl with intracranial sarcoma mimicking
mesenchymal chondrosarcoma, a 16 year old girl with broad ligament
sarcoma mimicking fibrosarcoma and a 5 month old girl with vaginal
sarcoma mimicking embryonal rhabdomyosarcoma showed DICER1-mutation. All
three tumors though seemingly diverse, had an uncanny resemblance,
comprising of a primitive mesenchyme-like spindle cell component with
rhabdomyoblastic differentiation on immunohistochemistry. Primitive
blastema, chondroid differentiation and foci of anaplasia mimicking
pleuropulmonary blastoma histology were variably present. One case
showed primitive neuroblastic differentiation. Though the constellation
of features reported in literature is quite varied, rhabdomyoblastic
differentiation has been ubiquitously reported in tumours across sites.
Molecular testing showed gain of chromosome 8 in 2 cases. All 3 cases
responded to alternating Vincristine, doxorubicin and cyclophosphamide /
Cisplatin, etoposide and ifosfamide (VDC/PEI) backbone followed by
maintenance chemotherapy. Conclusion - We highlight this morphologic
hallmark of rhabdomyoblastic differentiation with or without chondroid
differentiation, in primitive appearing pediatric sarcomas, especially
of female genital tract and brain, which should raise a flag to test for
DICER1 pathogenic variation. This is crucial in low / middle income
countries where sequencing is not done routinely. Timely diagnosis can
ensure appropriate treatment and implementation of surveillance
protocols for those with germline mutation.
Impaired function of PD-1+ follicular regulatory T cells in systemic lupus erythematosus
Authors: Kurata Izumi , Mikami Natsuko , Ohyama Ayako , Osada Atsumu , Kondo Yuya , Tsuboi Hiroto , Sumida T , Matsumoto Isao
Published: June 2021

Aberrant autoantibody production is characteristic of systemic lupus
erythematosus (SLE), but follicular regulatory T (TFR) cells potentially
can suppress this abnormality. We investigate functional changes in TFR
cells from SLE patients. Circulating TFR cells were collected from 19
SLE patients and 14 healthy controls (HC) to compare molecular
expression and in vitro suppressive capacity of follicular helper T
(TFH) cell proliferation. To reveal the stability of Foxp3 in TFR,
pyrosequencing of conserved non-coding sequence (CNS) 2 at the Foxp3
gene locus was performed. We then tested IL-2 in SLE-TFR cells to check
restoration of suppressor function. Programmed death-1 (PD-1) expression
in SLE-TFR cells was positively correlated with anti-DNA antibody levels
and disease activity. These cells had impaired suppressive function for
TFH cells with decreased expression of suppression mediators forkhead
box p3 (Foxp3), cytotoxic T-lymphocyte antigen 4 (CTLA4), and IL-2
receptor alpha (IL2Rα). Pyrosequencing identified hyper-methylation in
CNS2 region of SLE-TFR cells comparing to HC. With In vitro IL-2
stimulation, PD-1 expression of TFR cells significantly decreased along
with increased expression of Foxp3 and CTLA-4, especially in low-dose.
Thus, SLE-TFR cells have functionally defective to TFH suppression, but
low-dose IL-2 therapy might be useful to restore this ability.
Practical application of surveying methods for determination of volume quarry mining
Authors: Celms Armands , Pukite Vivita , Reke Ilona , Balevičius Giedrius , Ozolina Sandija
Published: June 2021

Nowadays, various types of geodetic measuring instruments are available in surveying. When conducting a survey of a terrain, surveyor must choose a survey method that is capable of providing high precision measurements. In the surveying process, it is possible to use the following measurement methods - tachymetric survey method, positioning method and remote sensing method. Each of the methods produces data formats that can be used further for volume calculations.
The paper analyses the volume differences that are obtained when using various survey methods and volume calculation programs to obtain the surface model. The use of such a tool is important for useful mineral miners, so that surveyors make qualitative surveys and obtain accurate and reliable volumes.
Useful minerals miners are required to report annually on their mining volume for a specified period. The useful minerals miners shall at all times keep records of the quantities of minerals actually extracted. Regardless of the type of accounting, topographic surveying and the calculation of volumes, if mineral is extracted in mineral deposits of national importance, more than 50 000 m3, are required (Augstas detalizācijas topogrāfiskās…, 2012). High-quality and accurate topographic survey is needed to create the most realistic surface model appropriate to the terrain. It is defined that the difference between the volumes obtained from the recording of vehicle loads should not be more than 5% when comparing the result of the mineral extraction from topographic surveys (Derīgo izrakteņu ieguves…, 2012; Noteikumi par valsts…, 2018). Nowadays, various measurement methods can be used to obtain data from which a surface model can be generated, and this model can then be used for volume calculations. The surface model is a set of points where, in addition to plane coordinates (x and y), there is also altitude (z) known (Luukkonen, 2011). Each measurement method has its own different measuring instruments that can be used, each method has its own operating principles, on which the quality and accuracy of the obtained data depends.
Is the Consensual Threshold for Defining High Glucose Variability Implementable in Clinical Practice?
Authors: Julla Jean-Baptiste , Jacquemier Pauline , Fagherazzi Guy , Vidal-Trecan Tiphaine , Juddoo Vanessa , Jaziri Asma , Mersel Hanane , Venteclef Nicolas , Roussel Ronan , Massin Pascale , Couturier Aude , Gautier Jean-François , Riveline Jean-Pierre
Published: June 2021

OBJECTIVE

Estimating glycemic variability (GV) through within-day coefficient of variation (%CVw) is recommended for patients with type 1 Diabetes (T1D). High GV (hGV) is defined as %CVw > 36%. However, continuous glucose monitoring (CGM) devices provide exclusively total CV (%CVT). We aimed to assess consequences of this disparity.

RESEARCH DESIGN AND METHODS

We retrospectively calculated both %CVT and %CVw of consecutive T1D patients from their CGM raw data during 14 days. Patients with hGV with %CVT >36% and %CVw ≤36% were called the “inconsistent GV group”.

RESULTS

A total of 104 patients were included. Mean ± SD %CVT and %CVw were 42.4 ± 8% and 37.0 ± 7.4% respectively (P < 0.0001). Using %CVT, 81 patients (73.6%) were classified as having hGV, whereas 59 (53.6%) using %CVw (P < 0.0001) corresponding to 22 patients (21%) in the inconsistent GV population.

CONCLUSIONS

Evaluation of GV through %CV in patients with T1D is highly dependent on the calculation method and then must be standardized.
Accuracy of Dexcom G6 Continuous Glucose Monitoring in Non–Critically Ill Hospitalized Patients With Diabetes
Authors: Davis Georgia M. , Spanakis Elias K. , Migdal Alexandra L. , Singh Lakshmi G. , Albury Bonnie , Urrutia Maria Agustina , Zamudio-Coronado K. Walkiria , Scott William H. , Doerfler Rebecca , Lizama Sergio , Satyarengga Medha , Munir Kashif , Galindo Rodolfo J. , Vellanki Priyathama , Cardona Saumeth , Pasquel Francisco J. , Peng Limin , Umpierrez Guillermo E.
Published: June 2021

OBJECTIVE

Advances in continuous glucose monitoring (CGM) have transformed ambulatory diabetes management. Until recently, inpatient use of CGM has remained investigational, with limited data on its accuracy in the hospital setting.

RESEARCH DESIGN AND METHODS

To analyze the accuracy of Dexcom G6, we compared retrospective matched-pair CGM and capillary point-of-care (POC) glucose data from three inpatient CGM studies (two interventional and one observational) in general medicine and surgery patients with diabetes treated with insulin. Analysis of accuracy metrics included mean absolute relative difference (MARD), median absolute relative difference (ARD), and proportion of CGM values within 15, 20, and 30% or 15, 20, and 30 mg/dL of POC reference values for blood glucose >100 mg/dL or ≤100 mg/dL, respectively (% 15/15, % 20/20, % 30/30). Clinical reliability was assessed with Clarke error grid (CEG) analyses.

RESULTS

A total of 218 patients were included (96% with type 2 diabetes) with a mean age of 60.6 ± 12 years. The overall MARD (n = 4,067 matched glucose pairs) was 12.8%, and median ARD was 10.1% (interquartile range 4.6, 17.6]. The proportions of readings meeting % 15/15, % 20/20, and % 30/30 criteria were 68.7, 81.7, and 93.8%, respectively. CEG analysis showed 98.7% of all values in zones A and B. MARD and median ARD were higher in the case of hypoglycemia (<70 mg/dL) and severe anemia (hemoglobin <7 g/dL).

CONCLUSIONS

Our results indicate that CGM technology is a reliable tool for hospital use and may help improve glucose monitoring in non–critically ill hospitalized patients with diabetes.
Kirken som organisme og organisasjon. Ekklesiologiske og organisasjonsteoretiske perspektiver på kirken som felleskap
Authors: Sirris Stephen , Askeland Harald
Published: June 2021

Due to the complexity of its functions, the church can be understood in various disciplines which offer different perspectives, concepts and metaphors. This chapter explores how theology and organizational sociology conceptualize the church as a collective. We aim at establishing a dialogue on the collective notion of the church as a religious organization using the concepts organism and organization as applied in the theological discipline of ecclesiology and utilizing insights from organization theory. Both hold that the church is a gathering of people coming together for religious purposes. Starting with a shared understanding of the collective, we present relevant insights from both domains. We analyze selected contributions in each tradition that enable an ongoing dialogue between them. The chapter argues that cross-disciplinary perspectives are beneficial to developing church organization.
PENENTUAN TIPE ISOTERM SORPSI ZAT WARNA REMAZOL GOLDEN YELLOW 6 MENGGUNAKAN JAMUR MATI RHIZOPUS SP HASIL ISOLASI DARI TEMPE
Authors: Rusmaya Deni , Nugroho Fadjari Lucia , Purwanti Tita
Published: June 2021

Industri tekstil biasanya menghasilkan limbah berwarna yang berasal dari proses pembilasan/pencucian kain. Seringkali limbah cair industri tekstil langsung dibuang ke sungai pada saat-saat tertentu. Penanganan permasalahan yang timbul dari pencemaran limbah cair tekstil dapat dilakukan melalui pengolahan secara biosorpsi. Biosorpsi merupakan suatu alternatif dalam proses pengolahan zat warna dari air buangan. Biosorpsi adalah serapan yang dilakukan oleh mikroorganisme. Dalam penelitian ini, zat warna yang diolah secara biosorpsi oleh suatu biakan murni jamur mati Rhizopus sp adalah zat warna RGY 6 yang merupakan zat warna reaktif dengan kromofor dari gugus azo. Biakan murni jamur mati Rhizopus sp merupakan jamur hasil isolasi dari tempe. Kapasitas adsorpsi menggunakan persamaan isoterm yang terpilih. Biosorpsi terhadap zat warna RGY 6 oleh jamur mati Rhizopus sp dilakukan dengan variasi konsentrasi zat warna 60 mg/L, 80 mg/L dan 100 mg/L, serta variasi berat jamur 0,05 gr; 0,14 gr; 0,23; gr 0,32 gr; 0,41 gr dan 0,5 gr. Isoterm penyisihan zat warna RGY 6 menggunakan jamur mati Rhizopus sp mengikuti pola isoterm Langmuir. Kapasitas adsorpsi jamur mati Rhizopus sp terhadap penyisihan zat warna RGY 6 pada konsentrasi 60 mg/L, 80 mg/L dan 100 mg/L masing-masing sebesar 70,922 mg/gr; 156,25 mg/gr dan 243,902 mg/gr. Kenaikan konsentrasi zat warna memberi pengaruh pada kapasitas adsorpsi yaitu dengan meningkatnya kapasitas adsorpsi. Konsentrasi awal memberikan suatu daya pendorong yang penting untuk mengatasi semua perlawanan perpindahan massa zat warna dari fase larutan ke fase padat (adsorben), sehingga konsentrasi zat warna yang lebih tinggi dapat mempertinggi kapasitas adsorpsi. Kata kunci : biakan murni jamur mati Rhizopus sp, biosorpsi, isoterm sorpsi, zat warna tekstil RGY 6
Turvallisuuden edistäminen iäkkäiden tehostetussa palveluasumisessa
Authors: Kiljunen Outi , Välimäki Tarja , Partanen Pirjo , Kankkunen Päivi
Published: June 2021

Turvallisuus on olennainen osa sosiaali- ja terveydenhuollon palvelujen laatua. Asumispalveluyksiköissä asuvien iäkkäiden turvallisuuden edistäminen edellyttää monenlaisia toimia, sillä huomioon tulee ottaa asumisen, hoidon, hoivan ja tukipalvelujen turvallisuus. Kattava kuvaus asukasturvallisuuden edistämisen toimista asumispalveluyksiköissä puuttuu. Tässä artikkelissa kuvataan asukasturvallisuuden edistämistä iäkkäiden tehostetussa palveluasumisessa dokumenttianalyysin pohjalta. Tutkimusaineisto koostui iäkkäiden palveluja ja asumispalveluyksiköitä Suomessa koskevista laeista, suosituksista, määräyksistä ja ohjeista (n = 26). Aineisto analysoitiin temaattisella analyysillä. Tulosten mukaan asukasturvallisuutta edistetään iäkkäiden tehostetun palveluasumisen yksiköissä suunnitelmallisella omavalvon-nalla ja omatoimisella varautumisella, moniammatillisella yhteistyöllä sekä lupa- ja valvontaviranomaisten toimilla ongelmatilanteissa. Asukasturvallisuuden edistämisessä korostuu johdon vastuu, mutta omavalvonta kuuluu jokaiselle yksikön työntekijälle. Lisäksi tulisi hyödyntää omaisten ja asukkaiden palaute, näkemykset ja huomiot asukasturvallisuudesta. Moniammatillista yhteistyötä tarvitaan asumisen ja palvelujen turvallisuuden takaamiseksi. Esimerkiksi terveydenhuollon asiantuntemusta tulee olla käytettävissä riittävästi. Pyrittäessä edistämään iäkkäiden asumispalveluyksiköissä asuvien turvallisuutta on tärkeää tiedostaa eri tahojen roolit sekä varmistua riittävästä osaamisesta ja resurssista asukasturvallisuustyössä.
Development of Speaking Skills Assessment Criteria for Engineering Students
Authors: Kornieva Zoia , Vashchylo Olha
Published: June 2021

The purpose of the article is to put forward English monologue production assessment criteria to verify the efficiency of the devised methodology of teaching English for future mechanical engineers. In the course of the research, theoretical, empirical, and statistical methods have been used. Various approaches to identifying the assessment criteria have been thoroughly analyzed. Seven criteria to assess the monologue production skills, five primary and two secondary ones, have been suggested. The allocation of the points by every criterion according to the devised scales have been elucidated. The proposed assessment criteria were used in the methodological experiment that was held at Igor Sikorsky Kyiv National Technical University. The experiment in question aimed to verify the efficiency of the devised methodology of teaching English monologue production to students majoring in mechanical engineering. Three experimental groups, 34 students in total, studying in their final year of Bachelor studies within the Subject Areas of Applied Mechanics and Industrial Engineering, participated in the methodological experiment. The conducted experiment confirmed the efficiency of the methodology proposed.
INTERTEXTUALITY REALIZATION IN SARI MATUA CEREMONY
Authors: Hutagalung Dyan Yosephin , Pulungan Anni Holila , Husein Rahmad .
Published: June 2021

ABSTRACTThis study aims to describe the realization of intertextuality occurences in sari matua ceremony. This research is conducted qualitatively by applying technique analysis of Bazerman. The data are utterances which delivered by the speakers in the ceremony and transcribed into transcription. Sari Matua is one kind of death ceremony in batak toba culture and has been studied in other particular field of study. In this study, intertextuality occurrence are studied on oral discourse in Sari matua batak toba ceremony. Sari matua batak toba ceremony consisted of two sessions which are Martonggo Raja and  main ceremony and this study focuses on these two sessions. The result of this study shows that there were 50 specific data found from 82 specific data which included kinds of intertextuality namely qutotation, reference, and allusion. The realization of intertextuality occurences in sari matua Batak Toba ceremony is realized by some elements of intertextuality itself. The realization  Quotation is identified through the presence of lexical expressions such as mandok, manungkun, hatahononku, di dok, pinasihat. Reference is identified by seeing clause which reflected to, re-contextualized to dan re-accentuated to. Allusion is  identified by clause complex which referring the text to literature, historical art, story, person even place. The intertextuality occurences realized in sari matua Batak Toba ceremony because the text which quoted, referred to and alluded to from the past time can be reflected in ourlives in the present time. Key words:  Intertextuality, Oral Discourse, Batak Toba Ceremony, Sari Matua
REALIZATION OF INTERTEXTUALITY IN EDITORIALS OF PRESIDENTIAL ELECTION 2019
Authors: Hasibuan Elsi Revita , Pulungan Anni Holila , Murni Sri Minda
Published: June 2021

ABSTRACTA text can be only interpreted through a background information of other text, and this is where intertextuality emerged, to shape another text. This study investigates the realization of intertextuality in articles of opposite editorials related to Presidential Election 2019. The objectives of the study is to evaluate the ways of the intertextuality realized. This research applied qualitative research design. The data were complex clauses which contained of intertextuality from opposite editorials of four newspapers, namely Kompas, Media Indonesia, Analisa, and Waspada started from January 2nd until April 17th 2019. The data were analyzed by using content analysis technique proposed by Elo and Kyngas (2007). The findings showed that; there were five elements those caused intertextuality realized in opposite editorials, they were; paraphrasing, patchwriting, making implicit meaning, putting contrastive conjunction, and last, image building. Keywords: Intertextuality, Realizations, Editorials, Presidential Election, Content Analysis
THE EFFECT OF COLLABORATIVE WRITING TECHNIQUE AND BRAINSTORMING TECHNIQUE AND STUDENTS CURIOSITY ON STUDENTS WRITING ACHIEVEMENT
Authors: Nasution Dina Maryadi , Pulungan Anni Holila , Ginting Siti Aisyah
Published: June 2021

ABSTRACTThe objective of this research is to explain wheter are students’ writing achievement taught by using collaborative writing technique is higher than that taught by using brainstorming writing technique. Because students more than active to make writing cooperatively. While the brainstorming writing technique ordered the students to make writing individually. The research design was experimental with research by using factorial design 2 x 2. There were 34 students from 2020/2021 academic year of Madrasah Aliyah Swasta Awashliyah 30 Binjai as the sample of this research.the students were divided into two groups. The first group was treated by using collaborative writing technique and the second group was treated by using brainstoring writing technique in writing achievement. The data were analyzed by applying ANNOVA. The result of the research that student’s writing achievement high curiosity with the mean score 83.35 higher than those with low curiosity eith the mean score is 82,29 and the Fobserved = 65.680 > Ftable 0.002.  It means that students with high curiosity affect students writing achievement higher than students with low curiosity.Keywords: Writing TeachingTechniques, Students’ Curiosity, Writing Achievement
CONVERSATION IMPLICATURE OF ARSY AND ARSYA IN YOUTUBE CHANNEL
Authors: Auliyah Nia . , . Sumarsih . , Saragih Amrin .
Published: June 2021

ABSTRACTThe aims of this study were to describe the kinds of  Conversational Implicarture, to explain the ways of performing implicature  and to describe the contex of implicature by Arsy And Arsya in Youtube channel. This research was conducted by using qualitative descriptive design. The data were the utterences of  Arsy and Arsya in Youtube Channel. The data analyzes by using theory of conversational implicature.the result of this study were 1) the kinds of conversational implicatures used by Arsy and Arsya  found in the text, they are Qualitative Maxim, Quantitative Maxim, Relevant Maxim, and Mannner Maxim. The analysis has found that Quantitative appeares in Arsy and Arsya YouTube Channel. (2)The process of conversational implicatures used by Arsy and Arsya in Wonderland YouTube Channel is realized through politeness strategies. (3) The reasons of the realization of conversational implicatures used by Arsy and Arsya in Wonderland YouTube Channel is realized through the system of tenor formed as [unequal/informal/positive/frequent]. It is found that there are are four. They are involved Bald on Record, Positive Politeness, Negative Politeness, and Off the Record. Off the record is the higher result found. Since she give codes to the hearer to get what her intentions, and it sometimes coded by gesture. . While in Arsya’s utterances, the types of politeness implicatures found are three. They are involved Bald on Record,Positive Politeness, and Off the Record. Off the record is the higher result found. Since she give codes to the hearer to get what her intentions, and it sometimes coded by gesture.  Keywords: Implicature, Conversational Implicatur, Politeness, Tenor, Interaction
As Comunidades Rurais da Gália Tardo-Romana: consumo, ascensão social e crise
Authors: Silva Uiran Gebara da
Published: June 2021

Este artigo tem como problema central a compreensão dos padrões de vida das comunidades rurais do Norte da Gália tardo-romana. Inicialmente apresenta uma reflexão teórica sobre as definições conceituais utilizadas e o impacto da mudança de paradigma no estudo da sociedade e economia tardo-romana (do “Declínio e Queda” para o da “Continuidade da Romanitas”) sobre o estudo das comunidades rurais. Em seguida problematiza a cultura material das regiões rurais em termos de fenômenos visíveis e invisíveis e, a seguir, analisa dados oriundos de estabelecimentos rurais observando e propondo alguns modelos de interpretação das relações sociais, econômicas e culturais em algumas regiões da Gália romana. O artigo conclui propondo a elaboração de modelos e categorias que, a partir de uma compreensão mais fina das comunidades rurais, possam representar também de forma mais complexa suas formas de organização comunitária.
Considerações sobre o conceito de campesinato para Alta Idade Média
Authors: Cardoso Daflon Eduardo
Published: June 2021

Para abordar uma série de realidades rurais, temporal e espacialmente diversas, é frequente a mobilização do termo “camponês” que tem uma larga tradição de estudos existente nas Ciências Humanas que remonta pelo menos ao século XIX. Porém, desde os anos 1980 houve uma redução expressiva no número de trabalhos com foco nesses agentes sociais. Para o mundo pré-capitalista em geral – e o medieval em particular – temos a existência de sociedades cuja absoluta maioria da população vive no campo e tira seu sustento majoritariamente do trabalho agrícola. Por sua vez, esses longevos anos de reflexão sobre o campesinato não encontraram eco marcante nos estudos do medievo, com aqueles que trabalhavam o solo merecendo de medievalistas comparativamente muito menos atenção que a aristocracia.  Apesar disso, o termo “camponês” não é raro, aparecendo normalmente desprovido de uma reflexão conceitual mais aprofundada. O presente trabalho busca argumentar que a aplicação de uma conceituação mais precisa do campesinato permitirá ganhos analíticos e de compreensão historiográfica desse grupo internamente e historicamente heterogêneo. Para tanto, elabora-se uma breve revisão da bibliografia disponível e com base nela propõe-se uma maneira de abordar teoricamente o campesinato (alto)medieval.
Cikkismertetés: Vajon a tejtermékek fogyasztása csökkenti a szív- és érrendszeri betegségek kockázatát és az ebből adódó halálozást?
Authors: Erdei Gergő
Published: June 2021

A „The Prospective Urban Rural Epidemiology (PURE)” vizsgálat egy nagy epidemiológiai kohorsz tanulmány, 35-70 éves személyek részvételével. A vizsgálat 5 kontinens 21 országban valósult meg. A vizsgálatban 136 384 fő élelmiszerfogyasztási gyakoriság kérdőívének eredményét értékelték. A közlemény elsődleges célja, hogy értékelje a tejtermék fogyasztása – ide értve a tejet, joghurtot, sajtot – valamint a szív- és érrendszeri megbetegedések és a mortalitás közötti összefüggést. Az eredmények alapján a tejtermékek jelentős bevitele (>2 adag/ nap vs. 0 adag/nap) alacsonyabb kockázatot jelent többek között a teljes mortalitás (0,83, 0,72–0,96; ptrend=0,0052), a főbb szív- és érrendszeri betegségek (0·78, 0·67–0·90; ptrend=0·0001), és a stroke (0·66, 0·53–0·82; ptrend=0·0003) esetében. Ugyanakkor nem figyelhető meg szignifikáns összefüggés a miokardiális infarktus esetében (HR 0,89, 95% CI 0,71–1,11; ptrend=0,163). Az eredmények között említik, hogy a vajbevitel alacsony volt és nem mutat szignifikáns összefüggést a klinikai kimenetelekkel (HR 1·09, 95% CI 0·90–1·33; ptrend=0·4113). Jelen vizsgálat eredményei azt mutatják, hogy a tejtermékek jelentős bevitele alacsony kockázatot jelent a mortalitással, szív- és érrendszeri betegségekkel kapcsolatban, különös tekintettel a stroke-ra. TANULSÁGOK A HAZAI SZAKEMBEREK SZÁMÁRA Jelen vizsgálat, összhangban hazai és nemzetközi táplálkozástudományi ajánlásokkal, javasolja a tej és a tejtermékek fogyasztásának növelését. A tanulmány felhívja a figyelmet arra, hogy különösen az alacsony és közepes jövedelemmel rendelkezők csoportjában szükséges a tej és tejtermék fogyasztásának növelése, ahol a beviteli mennyiségek jóval a javasolt fogyasztási mennyiségek alatt vannak.
Cikkismertetés: A haldokló baktériumok lehetővé teszik a növekedést és a túlélést mások számára antimikrobiális vegyületek felszívásával
Authors: Gajdács Márió
Published: June 2021

A kórokozó baktériumok számos stratégiával rendelkeznek az antibiotikumok pusztító hatásának túlélésére: rezisztenciájukat többféle molekuláris mechanizmuson keresztül képesek kifejezni (többek között a szer lebontása, kipumpálása vagy a célpontjának megváltoztatása mutációk által), vagy biofilmekbe ágyazva élik túl a gyógyszerek hatását. A Princeton és a Kalifornia Állami Egyetem (CSUN) kutatóinak új eredményei rávilágítottak egy újabb lehetséges mechanizmusra: az önfeláldozásra a baktériumpopuláción belül.
Cikkismertetés: Hogyan növelhetjük egyszerű változtatásokkal a gyermekek iskolai gyümölcsfogyasztását?
Authors: Devosa Iván
Published: June 2021

A felmérések szerint a legtöbb gyermek zöldség- és gyümölcsfogyasztása elmarad az étrendi ajánlásoktól. A szerzők egyszerű, alacsony költségvetésű magatartástudományi kísérlettel kívánták ösztönözi a gyermekeket arra, hogy az iskolai étkezdében több zöldséget és gyümölcsöt fogyasszanak ebédre.
Cikkismertetés: Az iskolai klíma és az egészségi állapot javítása középiskolában
Authors: Kis Bernadett
Published: June 2021

Az iskolai klíma egyaránt befolyásolja az egészséget és a teljesítményt, ezért az iskolai társas környezet javítása kiemelt jelentőségű lehet a serdülők egészségének és jóllétének fejlesztésében, különösen az alacsony és közepes jövedelmű országokban, ahol nagy a középiskolai évismétlések aránya.
Incidence of skeletal deformities in induced triploid rainbow trout Oncorhynchus mykiss (Walbaum, 1792)
Authors: Jagiełło Krzysztof , Polonis Marcin , Ocalewicz Konrad
Published: June 2021

Due to the cytogenetic incompatibility, triploid fish are usually infertile and are not affected by a decline in growth, survival and meat quality, which accompanies the process of sexual maturation in diploid specimens. Thus, artificial triploidization has been proposed for fish production in the case of species with early sexual maturation, such as rainbow trout. However, the use of this technique is limited by increased ratios of skeletal deformities observed in triploid specimens. The main objective of this research was to compare the proportion and variety of body abnormalities in diploid and triploid 14-month-old rainbow trout from commercial stocks, using external body shape examination, radiography and whole-mount skeletal staining. Individuals with externally observed body deformities (scoliosis, humpback, shortened tail and jaw deformities) accounted for 0.45% of the diploid stock and 3.83% of the triploid stock. X-rays and whole-mount skeletal staining of deformed individuals showed spine deformities, including compressions and fusions of vertebrae. Abnormalities observed in diploid and triploid rainbow trout examined during this study were non-lethal, however, they may negatively affect the condition of fish. Fish with skeletal deformities are not aesthetically pleasing, thus an increased ratio of such deformations in fish produced for commercial purposes may result in real economic losses.
Analisa dan Perbandingan PLTS on Grid yang Terpasang di Atap Gedung Utama PT Subur Semesta dengan Plts On Grid yang Bergerak Mengikuti Arah Matahari
Authors: Almanda Deni , Muttaqin Moh Akhsin Zaenal
Published: June 2021

Berdasarkan Permasalahan kebutuhan listrik di kalangan industri maka energi surya di pilih sebagai salah satu energi alternatif untuk menghasilkan energi listrik. Energi surya yang di hasilkan di siang hari bisa membuat penghematan daya berdasarkan cara pemasangan modul surya, pemakaian inverter yang sesuai dan instalasi standar yang terpasang. Pemasangan modul surya di atap gedung dengan pemasangan yang mengikuti arah matahari sangat berpengaruh pada energi listrik yang di hasilkan maka dari itu memaksimalkan keluaran listrik dari modul surya sangat di perlukan. Based on the problem of electricity demand in the industry, solar energy is chosen as an alternative energy to produce electrical energy. Solar energy generated during the day can make power savings based on how to install solar modules, use the appropriate inverter and standard installation installed. Installation of solar modules on the roof of the building with an installation that follows the direction of the sun is very influential on the electrical energy produced, therefore maximizing the electrical output of the solar module is very necessary.
Monitoring Suhu Kelembaban dan Polusi Udara Berbasis Raspberry Pi 3 dengan Menggunakan Transmisi Radio Frekuensi
Authors: Muchtar Husnibes , Hakiki Rahmat Sabar
Published: June 2021

Perkembangan ilmu pengetahuan teknologi saaat ini di tandai dengan bermunculan nya alat-alat yang menggunakan sistem kontrol digital dan otomatis, teknologi menjadi hal yangan sangat berguna bagi kehidupan manusia, mulai dari teknologi mekanik, listrik dan komunikasi yang sangat membantu aktivitas manusia agar lebih mudah dan lebih efisien.Penggunaan teknologi komunikasi sistem kontrol dan monitoring. Dalam hal ini pengontrolan menggunakan Handy talky sebagai komunikasi dan raspberry PI 3 sebagai pengontrolnya. Sensor untuk mendeteksi lingkungan sekitar dan LCD untuk menampilkan hasil sensor. The development of science and technology is currently marked by the emergence of tools that use digital and automatic control systems, technology is becoming a very useful thing for human life, ranging from mechanical, electrical and communication technology which greatly helps human activities to be easier and more efficient. efficient.Use of communication technology control and monitoring systems. In this case the controller uses Handy talky as communication and raspberry PI 3 as the controller. Sensors to detect the surrounding environment and LCD to display sensor results.
Monitoring Cuaca Berbasis Raspberry dengan Menggunakan Modul Lora
Authors: Bahri Saeful , Arif Andia Ridho
Published: June 2021

Cuaca merupakan faktor penting untuk kegiatan manusia dalam beraktivitas setiap hari oleh karena itu dibutuhkan pengamatan unsur cuaca. Dari pengamatan unsur cuaca  tersebut kita dapat mendapatkan informasi cuaca yang terjadi di wilayah tersebut sehingga masyarakat dapat mengetahui keuntungan maupun kerugian yang terjadi dengan kondisi cuaca tersebut. Saat ini masih terbatasnya alat monitoring  cuaca di masyarakat terutama pada wilayah yang tidak terjangkau internet. Oleh sebab itu pada penelitian ini dibuat sistem monitoring cuaca yang mengukur suhu,kelembapan,tekanan udara,arah angin dan deteksi hujan dengan menggunakan protokol nirkabel   Lora, Lora merupakan protokol nirkabel yang memiliki jarak jangkau lebih jauh dalam pengiriman data dibandingkan dengan teknologi nirkabel lainya sehingga cocok ditempatkan pada wilayah yang tidak terjangkau internet. Pada pengujian kinerja sistem monitoring cuaca ini Lora mampu mengirimkan data pada kondisi LOS sebesar 899 meter sedangkan pada kondisi NLOS sebesar 174 meter.Weather is an important factor for human activities in daily activities, therefore it is necessary to observe weather elements. From observing the weather elements, we can get weather information that occurs in the area so that people can find out the advantages and disadvantages that occur with these weather conditions. Currently, there are still limited weather monitoring tools in the community, especially in areas that are not covered by the internet. Therefore in this study a weather monitoring system was created that measures temperature, humidity, air pressure, wind direction and rain detection using the Lora wireless protocol, Lora is a wireless protocol that has a longer range in data transmission than other wireless technologies so it is suitable placed in areas that are not covered by the internet. In testing the performance of this weather monitoring system, Lora is able to transmit data at LOS conditions of 899 meters while in NLOS conditions of 174 meters.
Kontrol dan Monitoring Stop Kontak Berbasis Android
Authors: Dwisaputra Indra , Yudhi Yudhi , Anggrainy K’K , Novaldy Steven
Published: June 2021

Pertumbuhan konsumsi listrik semakin banyak dikarenakan pertumbuhan penduduk dan ekonomi dunia. Monitoring dan kontrol konsumsi energi listrik diharapkan dapat membantu efisiensi. Salah satu perangkat yang  digunakan menghubungkan sumber listrik ke perangkat listrik adalah elektrik soket. Penelitian ini dilakukan dengan cara eksperimen dan memodifikasi stop kontak yang umum di pasaran. Stop kontak ditambahkan sensor tipe PZEM-004T yang dapat membaca tegangan, arus dan daya. Data yang diambil dari sensor kemudian dibandingkan dengan alat power quality analyzer untuk mengetahui tingkat kepresisian pengukuran. Real time clock tipe DS3231 digunakan untuk menghitung pemakaian beban secara real time. Data diolah oleh mikrokontroller kemudian mengirimkannya ke Smart phone. Pengguna dapat memonitor biaya pemakaian dalam rupiah (Rp). Komunikasi stop kontak ke Smart phone menggunakan bluetooth tipe HC-05 dengan jarak maksimal 10 m. Relay dipasang untuk memutuskan aliran listrik sesuai dengan timer yang telah diatur. Berdasarkan hasil pengujian alat data yang dimonitoring memiliki perbedaan dengan persentase 0,13% untuk tegangan, 2,26% untuk arus dan 1,75% untuk daya. Aplikasi yang dibuat bekerja dengan baik dan dapat mengontrol ON/OFF sumber listrik pada stop kontak.The growth in electricity consumption is increasing due to population growth and the world economy. Monitoring and controlling the consumption of electrical energy is expected to help efficiency. One of the devices used to connect a power source to an electrical device is an electric socket. This research was conducted by experimenting and modifying common sockets on the market. The socket is added with a sensor type PZEM-004T which can read voltage, current and power. The data taken from the sensor is then compared with a power quality analyzer to determine the level of measurement precision. Real time clock type DS3231 is used to calculate load usage in real time. The data is processed by the microcontroller and then sends it to the smartphone. Users can monitor usage fees in rupiah (Rp). Communication socket to smartphone using bluetooth type HC-05 with a maximum distance of 10 m. Relay is installed to cut off electricity according to the timer that has been set. Based on the test results, the monitored data tool has a difference with a percentage of 0.13% for voltage, 2.26% for current and 1.75% for power.
Rancang Bangun Wastafel dan Portal Otomatis dengan Mempertimbangkan Antropometri Guna Mencegah Penularan COVID19
Authors: Hakim Muhammad Hanifuddin , Irmawanto Rudi , Poniman Poniman
Published: June 2021

Coronavirus yang merajalela pada tahun 2019 (Covid19) mempunyai karakteristik mudah menular, sehingga menjadikan virus ini sangat berbahaya. Meskipun Vaksin sudah ditemukan, protokol kesehatan masih harus diterapkan setidaknya selama 4 tahun kedepan. Salah satu protokol kesehatan yaitu selalu mencuci tangan dengan air mengalir dan sabun. Akan tetapi pada saat mencuci tangan, orang akan tetap menyentuh keran air dan botol sabun, padahal hal ini sangat berpotensi menjadi salah satu media penularan virus. Oleh karena itu penelitian ini bertujuan untuk menghindari sentuhan fisik saat mencuci tangan. Alat ini dilengkapi dengan portal pendeteksi suhu yang berfungi melakukan screening untuk memastikan orang yang akan masuk tidak sedang mengalami demam. Pengembangan teknologi dalam penelitian ini menggunakan metode rancang bangun (research and development). Desain yang dibuat mempertimbangkan Antropometri orang Indonesia. Sehingga Teknologi Tepat Guna (TTG) tersebut dapat memberikan rasa nyaman dan aman saat digunakan. Dari hasil pengujian alat, menunjukkan sensor MLX90614 (temperatur) memiliki tingkat kesalahan rata-rata pengukuran sebesar 0.213ºC atau sekitar 0.58%, sedangkan sensor PIR (jarak) memiliki tingkat sukses 90%. Secara keseluruhan sistem otomatis pada wastafel dan portal dapat berjalan dengan baik.The Coronavirus spread in early 2019 (Covid19) has characteristics of being easily transmitted, making this virus very dangerous. Even though the vaccines has been found, health protocols still have to be implemented for at least the next 4 years. One of the health protocols is washing hands with running water and soap. However, when washing hands, people still touch the water tap and soap bottles, even though this could potentially be a virus transmission media. Therefore, this study aims to avoid physical touch when washing hands. This tool is equipped with a temperature detector portal that functions to ensure that people who enter, do not have a fever. The technology development in this research uses research and development methods. The sink design is made considering Indonesian Anthropometry. Thus Appropriate Technology (TTG) can provide a sense of comfort and safety when used. From the test results, it shows that the MLX90614 sensor (temperature) has an average measurement error rate of 0.213ºC or about 0.58%. while the PIR (distance) sensor has a success rate of 90%. Overall the automatic system on the sink and portal can work well.
Rancang Pengolah Air Limbah Rumah Tangga Menggunakan Sistem Elektrokoagulasi
Authors: Isyanto Haris , Ibrahim Wahyu , Rizky Ahmad
Published: June 2021

Ketersediaan air tanah di beberapa kawasan hunian dan tempat tinggal mengalami penurunan setiap tahunnya, Seiring dengan banyaknya jumlah penduduk ini berpengaruh pada tingkat jumlah limbah cair terbuang, baik digunakan setelah digunakan mandi, maupun saat mencuci baju atau peralatan rumah tangga lainnya. Meningkatnya jumlah akan pembuangan limbah cair ini tidak diimbangi dengan kualitas dan kuantitas pengolahan air limbah, hal ini di buktikan dengan kasus-kasus pencemaran air yang terjadi di Indonesia. Untuk mengatasi hal tersebut diatas dibuat suatu rancangan pengolahan air limbah rumah tangga menggunakan sistem Elektrokoagulasi. Elektrokoagulasi adalah proses penggumpalan dan pengendapan pertikel halus yang terkandung pada air dengan menggunakan energi listrik. Proses ini dapat mengurangi kandungan supaya limbah air rumah tangga jika dibuang tidak mencemari lingkungan dan output dari hasil ini sesuai standarisasi limbah cair. Dari hasil pengujian Proses Elektrokoagulasi ini diperoleh bahwa pada pengujian tegangan berbeban pada proses Elektrokoagulasi didapatkan rata-rata Tegangan 8,97 Volt, Arus 5,42 A, Daya 48,63 Watt. Dan pada pengujian air didapatkan PH 6.5-8.7, dan TDS 389-556 mg/L. Dari hasil pengujian tersebut diperoleh hasil kadar kualitas air sudah sesuai memenuhi strandar, maka kadar air ini aman untuk dibuang tanpa mencemari lingkungan sekitar.The availability of groundwater in several residential and residential areas has decreased every year. Along with the large population, this has an effect on the level of wastewater that is wasted, whether used after bathing, or when washing clothes or other household utensils. The increasing number of wastewater discharges is not balanced with the quality and quantity of wastewater treatment, this is evidenced by cases of water pollution that have occurred in Indonesia. To overcome this, a design for household wastewater treatment using the electrocoagulation system was made. The electrocoagulation process is applied through coagulation processing with electrical energy in the electrolysis process to reduce ions in metals and particles in water. This process can reduce the content so that household water waste if disposed of does not pollute the environment and the output of this is according to the standardization of liquid waste. From the test results of the Electrocoagulation Process, it was found that the load voltage test in the Electrocoagulation process obtained an average Voltage of 8.97 Volts, Current 5.42 A, Power 48.63 Watts. And in the water test, the pH was 6.5-8.7, and the TDS was 389-556 mg / L. From the results of these tests, it was found that the water quality content was in accordance with the standards, so this water content was safe to dispose of without polluting the surrounding environment.
Rancang Bangun Alat Pendeteksi Medan Listrik Portable untuk Keamanan Manusia
Authors: Muchtar Husnibes , Sobirin Ridwan
Published: June 2021

Medan listrik yang ditimbulkan oleh peralatan listrik memiliki dampak buruk bagi manusia, medan listrik tidak dapat dilihat dengan mata manusia namun dampaknya dapat dirasakan oleh tubuh manusia, untuk mengetahui adanya medan listrik dan jarak terjauh medan listrik pada suatu peralatan listrik, maka diperlukan alat pendeteksi medan listrik. Metode yang digunakan Pada proyek akhir ini adalah menggunakan IC CMOS CD 4093 dan sistem mikrokontroller AtMega 328 P. Adapun langkah-langkah yang digunakan yaitu identifikasi kebutuhan alat, perancangan perangkat keras, perancangan perangkat lunak, dan pembagian data. Perencanaan sistem ini terdiri dari 4 bagian : sistem sensor, sistem pengolah data, sistem penampil data dan rangkaian Catu Daya.Sistem sensor menggunakan IC CMOS CD 40493 yang berfungi untuk mendeteksi keberadaan medan listrik pada peralatan yang menggunakan sumber listrik. Sistem pengolah data berupa sistem minimum menggunakan mikrokontroller Atmega 328 P untuk mengolah data yang dihasilkan oleh IC CMOS CD 4093, kemudian bagian berikutnya adalah penampil data berupa LCD (Liquid Cristal Display) dengan type modul M1632 LCD,  berfungsi untuk menampikan data yang ditangkap oleh sensor dan kemudian diolah pada sistem mikrokontroller Atmega 328 P kemudian ditampilkan pada LCD, Bagian terakhir yaitu rangkaian Power Supply, bagian ini sebagai penyedia catu daya agar rangkaian dapat bekerja semestinya.The electric field generated by electrical equipment has a bad impact on humans, the electric field cannot be seen with the human eye but its impact can be felt by the human body, to determine the presence of an electric field and the farthest distance from the electric field in an electrical equipment, an electric field detector is needed. . The method used in this final project is to use IC CMOS CD 4093 and AtMega 328 P microcontroller system. The steps used are identification of equipment requirements, hardware design, software design, and data sharing. This system planning consists of 4 parts: sensor system, data processing system, data display system and power supply circuit. The sensor system uses the CMOS CD 40493 IC which functions to detect the presence of an electric field in equipment that uses a power source. The data processing system in the form of a minimum system uses an Atmega 328 P microcontroller to process the data generated by the IC CMOS CD 4093, then the next part is a data viewer in the form of an LCD (Liquid Cristal Display) with the M1632 LCD module type, functions to display data captured by sensors and then processed on the Atmega 328 P microcontroller system then displayed on the LCD, the last part is the Power Supply circuit, this section serves as a power supply provider so that the circuit can work properly.
Rancang Bangun Sistem Pembangkit Listrik Tenaga Air Menggunakan Konsep Hydrocat
Authors: Anwar Syaiful , Tamam Muhamad Taufiq , Kurniawan Itmi Hidayat
Published: June 2021

Seiring perkembangan jaman, saat ini energi listrik telah menjadi salah satu kebutuhan primer dalam kehidupan sehari-hari, baik untuk melakukan pekerjaan ataupun kegiatan yang lainnya. Pembangkit Listrik Tenaga Air atau PLTA dengan menggunakan konsep hydrocat merupakan sebuah konsep pembangkit listrik yang diciptakan untuk aliran jalur irigasi yang memiliki ukuran tidak terlalu besar dan tingkat kedalamannya yang rendah. Oleh karena itu dibuatlah rancang bangun sistem pembangkit listrik menggunakan konsep hydrocat. Pada penelitian ini menggunakan generator DC sebagai sumber tenaga listrik dan menggunakan jenis turbin undershot. Penelitian ini dilakukan di Desa Karang Cegak Kecamatan Kutasari Kabupaten Purbalingga. Beban pada penelitian ini menggunakan lampu LED SMD 1,2 Watt, 2,4 Watt 3,6 Watt, dan 4,8 Watt. Alat ini mampu menghasilkan putaran pulley turbin air sebesar 69,2 rpm, 60,8 rpm, 59,0 rpm, 58,7 rpm, 57,1 rpm, dan 56,7 rpm. Putaran pulley generator DC sebesar 595,9 rpm, 586,1 rpm, 520,1 rpm, 506,2 rpm, dan 496,0 rpm. Besar tegangan yang dihasilkan 31,86 Volt, 9,20 Volt, 8,61 Volt, 8,38 Volt, dan 8,25 Volt. Besar arus yang dihasilkan sebesar 0,02 Ampere, dan besar daya yang dihasilkan sebesar 0,1836 Watt, 0,1718 Watt, 0,1671 Watt, dan 0,165 Watt.Along with the development of the times, nowadays electrical energy has become one of the primary needs in everyday life, both for doing work or other activities. Hydroelectric Power or Hydroelectric Power using the hydrocat concept is a power generation concept created for irrigation channel flow that is not too large and has a low depth level. Therefore, a power plant system design using the hydrocat concept was made. In this study using a DC generator as a source of electricity and using a type of undershot turbine. This research was conducted in Karang Cegak Village, Kutasari District, Purbalingga Regency. The load in this study uses 1.2 Watt SMD LED lamps, 2.4 Watt 3.6 Watt, and 4.8 Watt. This tool is capable of producing water turbine pulley rotation of 69.2 rpm, 60.8 rpm, 59.0 rpm, 58.7 rpm, 57.1 rpm, and 56.7 rpm. DC generator pulley rotation of 595.9 rpm, 586.1 rpm, 520.1 rpm, 506.2 rpm, and 496.0 rpm. The resulting voltages are 31.86 Volts, 9.20 Volts, 8.61 Volts, 8.38 Volts, and 8.25 Volts. The amount of current generated is 0.02 Ampere, and the amount of power generated is 0.1836 Watt, 0.1718 Watt, 0.1671 Watt, and 0.165 Watt.