bluuebunny/crossref_metadata_2025 huggingface dataset:
PRIVAÇÃO DO SONO E A SUSCETIBILIDADE A INFECÇÕES
Authors: Cipriano Sérgio Eduardo Miranda , Sousa Henrique Lima de
Published: December 2024

ABSTRACT

Insomnia is one of the most common complaints among individuals with psychiatric illnesses, including adults with depressive and anxiety disorders. Insomnia is not only a mental health problem, but also contributes independently to the risk of infectious and inflammatory diseases, as well as mortality from many causes. Therefore, this study aims to investigate the relationship between sleep deprivation and susceptibility to infections. The methodology used was a literature review, which involved searching for bibliographic materials in various databases, such as Scielo, PubMed and Google Scholar. A total of 12,100 publications were found, of which 12,086 were excluded, leaving 13 publications included in this study - 12 articles and one doctoral thesis. In the end, a significant and notable relationship between sleep and the immune system was observed, with sleep deprivation negatively affecting immune system function, making insomniacs more vulnerable to infectious conditions and pro-inflammatory states.
POR QUE HÁ UMA BAIXA ADESÃO AO DIU ENTRE AS MULHERES JOVENS?
Authors: Malta D. S , Santos F.C.F.F , Maximiano I.C , Costa L. F , Messora M. C , Ferneda M. E. B. G. R
Published: December 2024

This article aims to discuss the low adherence to the IUD contraceptive method, once the high PEARL Index has been proven. A survey was carried out with young women aged 18 to 25, to understand the factors that lead to the choice of another contraceptive method.
O USO EXCESSIVO DE TELAS E O DESENVOLVIMENTO NEUROPSICOMOTOR DE CRIANÇAS: UMA REVISÃO INTEGRATIVA
Authors: Giuberti Antonia Daniela Silva , Silva Antonia Dara Alves Da , Coelho Sara Ferreira
Published: December 2024

O uso excessivo de telas na infância está associado a impactos negativos no desenvolvimento neuropsicomotor, comprometendo habilidades sociais, atenção, sono e motricidade. Este estudo realizou uma revisão integrativa utilizando as bases de dados MEDLINE, LILACS, PEDro e SciELO, abrangendo artigos publicados entre 2019 e 2024. Os descritores utilizados foram “telas digitais” e “desenvolvimento infantil”. Os critérios de inclusão consideraram estudos primários publicados em inglês, português ou espanhol, enquanto textos duplicados e anteriores a 2019 foram excluídos. Os resultados demonstraram que a exposição prolongada às telas está associada a atrasos cognitivos, motores e emocionais, além de condições como obesidade e distúrbios do sono. O uso inadequado de dispositivos digitais prejudica a interação social e o aprendizado infantil. Estratégias como a limitação do tempo de tela e a promoção de práticas saudáveis são fundamentais. Este estudo destaca a necessidade de conscientizar pais, educadores e profissionais da saúde para incentivar um desenvolvimento infantil equilibrado.
Validity and Reliability of Self-administered Thai Pediatric Bleeding Assessment Tool (Pediatric-BAT) Application to Predict the Risk of Bleeding in Pediatric Bleed-ing Disorders
Authors: Suwanwijit Sisrimas , Chaweephisal Phumin , Sosothikul Darintr
Published: December 2024

Background: Congenital and acquired bleeding disorders present with various symptoms ranging from mild to severe manifestation. In recent years, attempts have been made to apply bleeding histories in questionnaires to predict the risk of bleeding and describe the symptoms’ severity. The Pediatric Bleeding Assessment Tool (BAT) is a pediatric-specific bleeding checklist set that has been accepted worldwide and was translated to multiple languages including Thai.
Objectives: (a) The study aimed to test the validity and reliability of the self-administered BAT and compare with the professional-administered BAT among Thai children with bleeding disorders, and (b) to descriptively evaluate severity using the self-administered BAT.
Method: This is a descriptive study of patients receiving a diagnosis of bleeding disorders treated at the King Chulalongkorn Memorial Hospital between 2019 and 2020. The patients were interviewed by a physician using the Thai version of the BAT application followed by a self-administered assessment over the next two weeks. Results were analyzed using mean and test-retest reliability by intra-class correlation (ICC).
Result: Totally, 41 eligible pediatric and adolescent patients, a median age of 10 years (ranged 2-20) were enrolled (17 with von Willebrand disease (VWD), 8 with severe hemophilia A, 3 with congenital factor VII deficiency and 13 with immune thrombocytopenia (ITP)). The total mean scores of self- and professional-administered BAT were 8.88 and 8.98 respectively (p = 0.819). However, subgroup analysis showed statistically significant differences between the two groups in diseases that have high BAT scores (severe hemophilia A and chronic ITP). The mean duration of the interview was 9.68 and 3.51 minutes, respectively (p <0.001). The score was also shown to depend on the disease and severity descriptively.
Conclusion: Self-administered BAT application is comparable with interviews by physicians in identifying the bleeding disorders and evaluating severity, but higher score need to be interpreted more carefully. The nondiagnosed mild bleeder may be encouraged to find medical attention, and known bleeders could also assess any severity change by themselves.
Work Motivation of Persons With Disabilities in UMKM Arsyadina Surabaya (Descriptive Qualitative Study)
Authors: Gendut Sukarno  , Mulik Khabibah
Published: December 2024

This study uses a descriptive qualitative method to analyze the intrinsic and extrinsic work motivation of individuals with disabilities at UMKM Arsyadina in Surabaya. Data was collected through interviews, observations, and documentation involving several informants, including the owner, non-disabled employees, and employees with disabilities who have worked for approximately two years. The data obtained was then analyzed using data condensation techniques, data presentation, and conclusion drawing. The results of the analysis indicate that individuals with disabilities have high motivation to work, driven by both internal and external factors. Moreover, the inclusive and adaptive work environment at UMKM Arsyadina contributes significantly to enhancing their work enthusiasm. These findings provide valuable insights into the motivational factors that enable individuals with disabilities to perform well in the workplace.
Strategies for Managing Non-Halal Funds in Sharia-Compliant Hotels Within the Context of CSR: A Perspective from Islamic Economic Law
Authors: Laras Annisa Ulfitri Nedi  , Nita Astuti  , Santi Susanti
Published: December 2024

One critical component in the rapidly expanding halal tourism industry is the existence of hotels catering to the needs of Muslim travelers, known as Sharia-compliant hotels. Operating within the framework of Islamic law, these hotels bear the responsibility of managing funds in accordance with Sharia principles. The management of non-halal funds within such establishments presents a complex challenge that necessitates careful consideration to ensure compliance with Islamic values while addressing financial and social aspects. This study aims to provide insights into strategies for managing non-halal funds in Sharia-compliant hotels within the framework of Corporate Social Responsibility (CSR) and from the perspective of Islamic economic law. Using a qualitative research approach with descriptive analysis through a literature review, the findings indicate that the legal status of non-halal funds may be permissible if allocated for general public welfare. Recommended management strategies include adherence to the PSAK 101 accounting standard and the application of Tafriq Shafqah principles through CSR initiatives. Non-halal funds are optimally distributed for social welfare (maslahah wa tashrif al-‘ammah) such as empowering local communities through education and training, supporting zakat and charity programs, promoting sustainable environmental management, ensuring fair employment opportunities, fostering local economic development, and enhancing public education and awareness. These efforts not only enhance the positive reputation of Sharia-compliant hotels but also contribute significantly to the economic, environmental, and social well-being of the broader community.
Building A Training Programme On The Dimensions Of Accountants' Professional Motivation And Its Impact On The Development Of Technical Literacy
Authors: Kadhim Al-Abboodi Mohammed , Fakhfakh Mondher
Published: December 2024

The research aims to build a training programme according to the dimensions of the professional motivation of accountants and its impact on the development of technical Literacy by verifying the validity of the following null hypothesis: "There is no statistically significant difference at the level of significance (0.05) between the average scores of accountants of the experimental group and those who will subject accountants to the training programme based on the dimensions of professional motivation and the average scores of accountants for the control group who will not subject accountants to training in the training programme in technical Literacy.To achieve the objectives of the research, the researchers used the experimental design with two equivalent groups (experimental and control), as 42 accountants were randomly selected (by lot) as a sample for research from the accountants of the General Directorate of Education of Qadisiyah for the academic year 2024-2025, by 21 accountants for the experimental group and 21 accountants for the control group.The training programme was built according to three stages (planning, design, evaluation), and then trained accountants of the experimental group for a period of (11) days by two sessions per day using the training programme according to the dimensions of professional motivation, and the researcher prepared a scale for technical Literacy of the type of multiple choice (40 items), and their sincerity and stability were verified, as the stability coefficient for testing the scale reached (90, 0) and the stability coefficient of the observation card was (0.86), for the scale test (0.89) and they were applied after the end of the experiment. And the researcher used the statistical programme SPSS.The accountants of the experimental group outperformed the accountants of the control group in the scale test, and in light of the results of the research, the researcher recommended the possibility of adopting the training programme prepared according to the dimensions of professional motivation.
Competency Analysis In Improving Government Financial Accountability: Literature Review
Authors: Devi Pertiwi Ananda Putri  , Indrawati Yuhertiana
Published: December 2024

This study aims to analyze competency in improving accountability. This study uses the System Literature Review method using data sources from Mendeley, Publish or Perish 8 and Google Scholar with journal indexes Sinta 1, Sinta 2 and Sinta 3 as well as reputable international journals over a period of 5 years starting in 2019-2024. Article collection was carried out using the keywords competency and accountability. The results of this study indicate that competency formed by intellectual and physical abilities affects accountability and transparency, especially in village governance. Inadequate competency in village officials can hinder effective fund allocation, impact accountability and risk misallocation of funds due to weak monitoring and evaluation systems. Human resources are the main asset, and increasing competency in financial management among village officials is related to increasing accountability, in line with management theory, which emphasizes responsible and honest governance.
Design and Implementation of an Electronic Administration (E-Admin) System for the Registry Unit of Federal Polytechnic, Ile Oluji, Nigeria
Authors: Ibiyomi Michael Adeniyi , Ajinaja Micheal Olalekan , Akeem Abiona Adekunle
Published: December 2024

The Registry Unit at Federal Polytechnic Ile Oluji currently relies on manual processes to manage critical staff, student, and council data. This approach is inefficient and prone to errors, emphasizing the need for an automated solution. This project aims to design and implement an Electronic Administration (E-Admin) system to streamline operations within the Personnel, Academic, and Council Affairs sub-units of the Registry Unit. The system was developed using web-based technologies to ensure easy access and seamless integration. Specific modules were designed for each sub-unit: The Personnel Unit manages staff information, the Academic Unit oversees student records, and the Council Affairs Unit coordinates council member activities. A user-friendly interface facilitates efficient data management. The E-Admin system automates key administrative functions, reducing manual paperwork and enhancing data accuracy. It enables effective management of staff appointments, student registrations, and council activities, improving coordination across sub-units. The implementation of the E-Admin system significantly enhanced operational efficiency, communication, and data accuracy within the Registry Unit. By digitizing administrative processes, the system increased productivity and streamlined data management, benefiting both staff and students at Federal Polytechnic Ile Oluji, Nigeria.
Modeling the Impact of Disease Transmission and Treatment Timing on Honey Bee Population and Honey Production
Authors: Shen Eric
Published: December 2024

Numerous complex dynamics exist within honey bee colonies regarding their population and honey production. Honey bees are essential for pollination and food security, but their populations are declining due to various factors such as disease, parasites, and environment. stresses. While there are numerous models for bee population and disease dynamics, few models also consider honey production. This study presents a mathematical model that integrates honey bee population dynamics, disease transmission, and honey production into a single comprehensive framework. Building off existing models, this model simulates the interactions between susceptible and infected hive and forager bees, along with honey resources. The results demonstrate how disease impacts the population of bees and the honey they produce. This model simulates the active and winter seasons, accounting for disease transmission and the effects of various types of treatment. Results show that early treatment leads to higher bee populations, while late treatment is more effective in eradicating the infection, but it also results in lower honey production.
Analysis of Interests in the Context of Security Needs. The Example of 'Corridor No.8'
Authors: Atanasov Plamen
Published: December 2024

This article proposes a methodology to identify key actors within the network of interests arising from specific challenges. Drawing from Niklas Luhmann's concept, this analysis emphasizes the importance of societal connections. An example is presented regarding the development of interests related to the construction of Corridor No. 8, as a challenge to regional security in the Balkans.
Калибриране на стратегическия компас за нова ера в европейската отбрана
Authors: Panayotova Monika
Published: December 2024

The publication aims on the one hand to show the strategic priority for a new era in European defence in the starting mandate of the European institutions (2024-2029), and on the other hand to draw certain conclusions about the Common Security and Defence Policy (CSDP) and the need to calibrate its Strategic Compass, taking into account the "inclination and deviation" in the course towards building the European Defence Union. Emphasis is placed on the need for an exponential way of strategic thinking, taking into account AI, climate, security and defence issues as cross-cutting elements for all EU policies.
TRAFFICKING AND VULNERABILITY OF THE GIRL-CHILD EDUCATION IN NIGERIA
Authors: OBI ALFRED IDIBHAR  , ZIPREBO TONYE
Published: December 2024

This paper investigates human trafficking and girl-child education in Nigeria. It is the practice whereby people, children and women are taken away from their homes to provide domestic labour or sexual services to people either within or outside of their country. Negative peer influence, depressed and poor national economy, Poverty, unemployment, ignorance on the part of victims of human trafficking, lack of parental guidance and control, greed, illiteracy/lack of education, and inadequate punishment for offenders are some drivers of the illegal act. Secondary sources of data were used for the analysis. Feminism theory was adopted as the theoretical framework. It has led the girl-child into hawking, prostitution, poverty, early and forced marriage as well as low self-concept. The following recommendations were made; fostering of social, economic and political stability, and the reduction both of migration caused by deep poverty, improve children’s access to educational and vocational opportunities, in particular by girls, enhancing job opportunities for women by facilitating business opportunities for small and medium-sized enterprises (SMEs). Developing programmes that offer livelihood options and include basic education, literacy, communication and other skills, and reduce barriers to entrepreneurship, and encouraging gender sensitization and education on equal and respectful relationships between the sexes, thus preventing violence against women.
Análisis ampliado del género, espacio y Geografía Feminista con perspectivas interseccionales y decoloniales
Authors: Herrera Vargas Lady Johanna
Published: December 2024

Este trabajo presenta una revisión ampliada de las contribuciones de la Geografía Feminista a la comprensión del género y el espacio. 
A partir de un análisis bibliográfico de tres artículos científicos, un libro y una tesis de maestría, se identificaron diez categorías de análisis clave y se construyó una conceptualización del género y el espacio desde la perspectiva de la Geografía Feminista. Se incorporan perspectivas interseccionales y decoloniales para enriquecer la discusión y ofrecer una visión más completa de las relaciones de poder en el espacio.
Resultados de Aprendizaje en Administración de Empresas: Análisis comparativo en las Modalidades Presencial y a Distancia en la Fundación Universitaria San Martín
Authors: Villamizar Berdugo Samuel Leonardo
Published: December 2024

La investigación se llevó a cabo en la Fundación Universitaria San Martín sede Bogotá, Colombia, y comparó los resultados de aprendizaje de los programas de Administración de Empresas en modalidades presencial y a distancia durante el primer semestre de 2023. 
Se analizaron 61 espacios académicos, encontrándose que, aunque ambas modalidades comparten similitudes en sus dinámicas académicas, existen oportunidades de mejora en la alineación de los resultados de aprendizaje con el perfil profesional deseado. 
En particular, se observó la necesidad de fortalecer habilidades de nivel superior como "Crear", "Evaluar", "Analizar" y "Aplicar".
Además, se identificó que los resultados en la categoría de "Recordar" no se ajustan a las metas para los graduados, sugiriendo la necesidad de redimensionar los perfiles profesionales para incorporar competencias relacionadas con la era digital y la industria 4.0.
Cultura organizacional - comunicacional y gestión de calidad, Universidad de Guayaquil, Ecuador, 2023
Authors: Cortez Corozo Joyce , Mármol Córdova María
Published: December 2024

El presente artículo se enfoca en el estudio de los valores en la organización, y la información que existe para el ordenamiento regular en la Universidad de Guayaquil.
Se trata del "Buen vivir" argumentando el bienestar de las personas y la sostenibilidad ambiental, rescatando el proceso innovador del Estado.
Del orden Institucional, los cuales proponen las IES, que la prioridad es lograr la calidad educativa con profesionales eficientes que facilitan el desarrollo en las organizaciones, con base a la idea prioritaria, que demuestra el estado activo y correlacional entre la docencia-organización e investigación-organización.
Del modelo educativo, en Latinoamérica ha contribuido al empoderamiento digital complementándose con la Inteligencia Artificial, pero demostrando la conexión ambigua tecnológica, comprometiéndose con la actualización de fuentes de la información; que con el tiempo se convierten en las áreas de estudio. 
Aplicando la rapidez de los contenidos que parcialmente demuestran la educación práctica, técnica y eficiente para la sociedad.
Entonces, el control de la comunicación, gestionando con frecuencia la información interna y externa en la organización, colaborando con cumplir los objetivos establecidos permanentemente para poder llegar a los públicos de acuerdo a la planificación de la Institución.
În loc de prefață
In memoriam Corneliu Pădurean (1952–2024).
O viață în slujba oamenilor și a istoriei
Authors:   Facultatea de Științe Umaniste și Sociale, Universitatea „Aurel Vlaicu” Arad, Pădurean Alina Nicoleta
Published: December 2024

In the following pages one can read about the life and career of prof. dr. Corneliu Pădurean, born in Arad in 1952. Professor Pădurean dedicated most of his life to the study of history, to population studies and demography, being one of the most important historians Arad ever had. A remarkable teacher, historian and researcher, Professor Pădurean pursued his childhood dream to become a respectable member of his community. He worked as teacher, school inspector, professor at “Aurel Vlaicu” University of Arad and the Doctoral School of the University of Oradea. He published books, studies, organized conferences and other scientific events, fighting to put his home town, Arad, on the map of academic cities in Romania. He was distinguished for his tireless work with several medals and distinctions, accepted as member in professional organizations and associations. Besides his outstanding professional activity, Corneliu Pădurean was a great father for his two children and an amazing grandfather for his nieces whom he loved deeply till the end of his days.
Mythology versus historical reality about the ideal of national unity during the Revolution of 1848-1849 in Transylvania
Authors:   Academia Română, Bolovan Ioan
Published: December 2024

In 1848, a series of simultaneous revolutions swept across Europe, moving from France towards the east, inflaming Germany, Italy, the Habsburg Empire, and the Romanian countries. Although the 1848–1849 Revolution was a manifestation of the entire Romanian nation, because of the specific circumstances in each province, it did not break out simultaneously, nor did it know the same development or intensity in all of them. Alongside the 2nd half of the 19th century and during the 20th century, several clichés which need to be amended developed in the Romanian historiography.
Scriitori români din anii comunismului național
în luptă cu iredentismul maghiar
Authors:   Facultatea de Istorie și Filosofie, Universitatea „Babeș Bolyai” Cluj Napoca, Mitu Sorin
Published: December 2024

This article deals with the attitude shown towards Hungarians by some Romanian writers form the period of national communism. Passages from the writings of Adrian Păunescu, Corneliu Vadim Tudor and Ion Lăncrănjan are analyzed. Demonizing the Hungarian enemy served as a useful ideological diversion for the Ceaușescu regime.
THE EFFECT OF APPLICATION TOWARDS CADETS’ ENGLISH ABILITY: A GREEN PLANET SUISTAINABILITY
Authors: Dewi Irma Shinta , Fatimah Fatimah , Fauziningrum Endah
Published: December 2024

There are many things should be prepared for the Human Resource (HR), to guarantee the promise future and career. The 5.0 era hopes that technology and human are going to live harmoniously in order to improve the quality of human life on an ongoing basis and facilitate the human interest. Meanwhile, in 4.0 era, the social ecosystem accesses a database in cyberspace from the internet and searches, retrieves and analyzes information or data. The society 5.0 is very dependent on cyberspace (visual room) and physical space.  In this era, the English ability is very important to achieve. Moreover, there should be any efforts to improve it. The purpose of this study is to describe the efforts of maritime educational institutions in facing the 5.0 era using applications affecting the cadet’s competence of English at PIP Semarang. This type of research is quantitative method with ‘one group pre-test post-test pre-experimental (non-design)’. To complete the data, it could be done by using observation, documentation and library research. Meanwhile the analysis of research data used validity and reliability. The results of the study showed that an application has affected to improve the cadet’ English ability. The conclusion is the application is one of the efforts of maritime education to face 5.0 era in education technology as consequently green planet sustainability.
PELUANG DAN TANTANGAN PENGUATAN PERAN PELABUHAN ACEH DALAM JARINGAN LOGISTIK LOKAL DAN NASIONAL
Authors: Kurniawan Dedi , Muzaroddin Ihrof , Azis Muhammad , Sabaruddin Sabaruddin
Published: December 2024

Pelabuhan memainkan peran penting dalam memastikan bahwa jaringan logistik nasional berjalan dengan baik. Pengembangan pelabuhan saat ini menjadi masalah utama dalam meningkatkan daya saing perekonomian lokal dan nasional karena meningkatkan ekonomi di Pelabuhan laut. Namun demikian pelabuhan di provinsi Aceh belum mengalami kemajuan yang signifikan yang ditunjukkan dengan aktivitas ekonomi yang masih sangat rendah. penelitian ini menggunakan deskripsi kualitatif melalui wawancara mendalam, kuesioner, dan survei lapngan langsung ke pelabuhan-pelabuhan di Aceh.Hasil penelitian menunjukkan bahwa sejumlah Pelabuhan di Aceh memerlukan peningkatan fasilitas untuk memenuhi standar nasional karena keterbatasan infrastruktur ini berpotensi menghambat pertumbuhan ekonomi lokal dan integrasi Pelabuhan Aceh ke dalam jaringan logistik nasional. Strategi utama dalam pengembangan pelabuhan di Provinsi Aceh adalah dengan menciptakan pusat pertumbuhan ekonomi di wilayah penyangga dengan mengembangkan sektor perikanan, pertanian, kehutanan, pertambangan dan penggalian, serta sektor industri untuk meningkatkan konektivitas jaringan logistik pelabuhan-wilayah penyangga dengan cara meningkatkan kualitas infrastruktur penghubung, meningkatkan kerja sama antar sektor seperti operator pelabuhan dengan eksportir dan penyedia jasa logistik, serta membangun terminal barang menjadi sangat penting untuk meningkatkan efisiensi.
ANALYSIS OF THE SUCCESS LEVEL OF DIRECT DISCHARGE QUARANTINE ON THE AMOUNT OF TARIFF TO BE PAID BY SERVICE USERS AT INDONESIAN CONTAINER TERMINAL COMPANY
Authors: Bahagianti Wenny Yovi , Sihaloho Otri Wani , Ratnaningsih Dyah , Beno Jose
Published: December 2024

Direct Discharge Quarantine is a code at Indonesian Container Terminal Company for the activity of unloading imported containers that have received a quarantine inspection flag by direct dischrage (direct unloading) to the quarantine inspection block (TPFT-Karantina). Accelerating the movement of containers during Direct Discharge Quarantine is very important in reducing the high stacking rates that must be paid by service users. This research aims to determine the percentage success rate of Direct Discharge Quarantine, determine the factors that hinder the success rate of Direct Discharge Quarantine, and analyze the comparison of the stacking rates when containers are subjected to quarantine inspection by Direct Discharge and Non-Direct Discharge.
This research uses mixed methods. Quantitative methods using descriptive statistical analysis techniques are used to obtain the percentage success rate of Direct Discharge Quarantine and a comparison of the amount of stacking rates when containers are subjected to quarantine checks via Direct Discharge and Non-Direct Discharge Quarantine. Qualitative methods using fishbone diagram analysis techniques were used to look for factors that influence the percentage success rate of Direct Discharge Quarantine. Based on the results of data processing in this research, it was found that the percentage success rate for Quarantine Direct Discharge was 71% and was included in the high success rate category. Factors that influence the percentage success rate for Quarantine Direct Discharge include machine, method, facility, measurement, and mother nature, the calculation results show that the quarantine inspection package rates and container stacking rates for both dry and reefer types using the Direct Discharge Quarantine mechanism are much cheaper with a difference of 30% when compared to Non-Direct Discharge Quarantine.
Blastocystosis And Iron Deficiency Anemia in Pregnant Women. A Call to Deep in A Little-Known Association
Authors:   Department of Parasitology, Institute of Tropical Medicine “Pedro Kouri”, Havana, Cuba, Fonte Luis
Published: December 2024

During the last twenty-five years, in parallel with the demonstration of
a rapid increase of the global prevalence of blastocystosis, it has been
documented the association between this parasitic infection and iron
deficiency anemia in general population. More recently, it has been
evidenced the high prevalence of blastocystosis in pregnant women
and its association with iron deficiency anemia. Herein, we revise
the most recent progress in the understanding of this association,
the possible mechanisms that support it, including the Blastocystis
subtypes involved, and its clinical consequences and public health
significance. Taken in consideration the adverse impacts of anemia
on the health of mothers and progeny, an adequate prevention and
control of this parasitism during pregnancy may be mandatory. At
the same time, and looking the problem from a more holistic multidiseasebased perspective, the current initiatives to improve the
prevention and control of intestinal parasitism in endemic areas may
include in their communication strategies actions to inform, both at
academic and community levels, about the possible adverse effects of
blastocystosis on pregnancy evolution.
Ziprasidone Does not appear to be Able to Modify the Rise in Blood Lipids Caused by Olanzapine in a Randomised Study
Authors:   Zhjiang province mental health center, Hangzhou, Zhejiang, China, Fengli Sun
Published: December 2024

observe the differences of blood lipids between
ziprasidone combined olanzapine and single ziprasidone in inpatients
with schizophrenia.
Swadhin Kalam Nepali
Authors: Chaudhary Divakar
Published: December 2024

Gopal Singh Nepali was a free-spirited person. He never compromised with principles in his life. This characteristic of his personality is definitely considered a weakness of his personality in the present opportunistic environment where even a donkey is made a father if needed. His personality has both fire and passion. He was a free-spirited person, self-respecting, a writer and a patriot. The expression of which is not only seen in his writings but also on the hard ground of behavior. His personality had its own mark among his contemporaries. Due to the qualities like simplicity, spontaneity, calmness of his personality, he had to face many kinds of crises in life. Even then his personality kept getting stronger and stronger, improving. He never compromised with wrong at the ideological and practical level. Many kinds of allegations were made on his personality, even then he did not stop, yes, he was definitely hurt. Even then he kept singing-

'The one who gave the sword to Shiva,

Gave the light on loan to Diva.

I gave the rudder to the waves,

Gave the edge of the dagger to the air.

The same creator of the world,

I put the pen under my control.

My wealth is the free pen.
‘Here, Kitty, Kitty, Kitty’
Authors: Schubart Rikke
Published: December 2024

This article explores the motifs of pet and play in the Alien franchise.It is grounded in biocultural theory and draws on play research fromanthropology, ethology, and linguistics (Huizinga, Burghardt, Bateson)and research in pets from animal studies and philosophy (Melson,Tuan, Fudge). The article develops three levels of play to discuss theaudience’s engagement: immersed play (play1), shifting in and outof a play frame (play2), and distanced looking-at-play (play3). Thepet function in the Alien series is performed by various beings, suchas the cat Jonesy and dog Spike, the Alien, the clone Ripley 8, andthe androids David and Walther. Pet and play have until now beenoverlooked in analyses of the franchise, but this article develops a newperspective that concludes with a reflection on the Alien as an animal"’good to think’" (Lévi-Strauss) with, in that the audience can use theAlien as play pivot in a game of pet domestication, domination, andmastery.
Wyłączenia stosowania dyrektywy w sprawie udzielania zamówień przez podmioty działające w sektorach gospodarki wodnej, energetyki, transportu i usług pocztowych – przegląd prawa i orzecznictwa unijnego w zarysie
Authors:   Uniwersytet w Bergen: Wydział Prawa, Herrera-Anchustegui Ignacio , Kraśniewski Marcin ,   Uniwersytet Łódzki: Wydział Prawa i Administracji, Katedra Europejskiego Prawa Gospodarczego (Zakład Prawa Gospodarczego Publicznego)
Published: December 2024

W niniejszym opracowaniu przedstawiono dotychczasową praktykę w zakresie przyznawania wyłączeń od stosowania dyrektywy Parlamentu Europejskiego i Rady z dnia 26 lutego 2014 r. w sprawie udzielania zamówień przez podmioty działające w sektorach gospodarki wodnej, energetyki, transportu i usług pocztowych, uchylającej dyrektywę 2004/17/WE. Zauważalna jest wzrastająca liczba pozytywnych decyzji Komisji w tym zakresie. Autorzy przyjmują, że z czasem pojedyncze wyłączenia dyrektywy sektorowej doprowadzą do wyłączenia całego sektora energetycznego lub jego znacznej części spod unijnych zasad udzielania zamówień publicznych. W artykule dokonano analizy podstaw prawnych przyznawania wyłączeń oraz wydanych na ich podstawie decyzji Komisji Europejskiej dla podmiotów prowadzących działalność gospodarczą w sektorze energetycznym.
Status prawny hulajnóg elektrycznych i ich użytkowników – projektowane rozwiązania i wzorce zagraniczne
Authors:   Uniwersytet Łódzki: Wydział Prawa i Administracji, Groblewski Maciej , Pater Michał ,   Uniwersytet Łódzki: Wydział Prawa i Administracji
Published: December 2024

W niniejszym artykule podjęto się próby analizy i oceny rozwiązań proponowanych w projektowanych ramach prawnych dla hulajnóg elektrycznych pod kątem uzyskania odpowiedzi na pytania dotyczące: statusu użytkowania hulajnogi, sposobu określenia praw i obowiązków użytkowania hulajnogi, statusu hulajnogi elektrycznej, czy proponowane rozwiązania są zgodne z trendami występującymi w ustawodawstwie innych państw, jaki model regulacji powinien przyjąć polski ustawodawca, czy projektowana ustawa jest kompletna. W niniejszej pracy autorzy wyróżniają cztery aspekty, które spowodowały potrzebę uregulowania: społeczny, technologiczny, ekologiczny, ubezpieczeniowy. Po omówieniu tych aspektów, w dalszej kolejności, autorzy poświęcają uwagę przebiegowi procesu legislacyjnego oraz proponowanym rozwiązaniom prawnym, co stanowi kluczowy punkt opracowania. Omówiony zostaje status urządzeń transportu osobistego, ich użytkowników, kwestie wymogów technicznych oraz obowiązków usługodawców z zakresu zapewnienia bezpieczeństwa wypożyczanych lub sprzedawanych przez nich urządzeń. Dalsza część opracowania, poświęcona jest omówieniu i analizie regulacji zagranicznych, dotyczących środków transportu osobistego, ze wskazaniem na występowanie w tym zakresie dwóch tendencji – konserwatywnej oraz liberalnej. Na zakończenie, autorzy starają odpowiedzieć się na pytanie badawcze postawione na wstępie, mając na uwadze, że inicjatywa ustawodawcza w tym zakresie była niezbędna i stanowi właściwą odpowiedź na zapotrzebowanie gospodarcze oraz społeczne. Rosnąca liczba hulajnóg elektrycznych, a także przedsiębiorstw, które zajmują się ich wynajmem sprawia, że koniecznym było wprowadzenie przepisów jednoznacznie określających status hulajnóg i ich użytkowników.
Projection neurons are necessary for the maintenance of the mouse olfactory circuit
Authors: Sánchez-Guardado Luis , Razavi Peyman , Wang Bo , Callejas-Marín Antuca , Lois Carlos
Published: December 2024

The assembly and maintenance of neural circuits is crucial for proper brain function. Although the assembly of brain circuits has been extensively studied, much less is understood about the mechanisms controlling their maintenance as animals mature. In the olfactory system, the axons of olfactory sensory neurons (OSNs) expressing the same odor receptor converge into discrete synaptic structures of the olfactory bulb (OB) called glomeruli, forming a stereotypic odor map. The OB projection neurons, called mitral and tufted cells (M/Ts), have a single dendrite that branches into a single glomerulus, where they make synapses with OSNs. We used a genetic method to progressively eliminate the vast majority of M/T cells in early postnatal mice, and observed that the assembly of the OB bulb circuits proceeded normally. However, as the animals became adults the apical dendrite of remaining M/Ts grew multiple branches that innervated several glomeruli, and OSNs expressing single odor receptors projected their axons into multiple glomeruli, disrupting the olfactory sensory map. Moreover, ablating the M/Ts in adult animals also resulted in similar structural changes in the projections of remaining M/Ts and axons from OSNs. Interestingly, the ability of these mice to detect odors was relatively preserved despite only having 1–5% of projection neurons transmitting odorant information to the brain, and having highly disrupted circuits in the OB. These results indicate that a reduced number of projection neurons does not affect the normal assembly of the olfactory circuit, but induces structural instability of the olfactory circuitry of adult animals.
Amoeboid cells undergo durotaxis with soft end polarized NMIIA
Authors: Kang Chenlu , Chen Pengcheng , Yi Xin , Li Dong , Hu Yiping , Yang Yihong , Cai Huaqing , Li Bo , Wu Congying
Published: December 2024

Cell migration towards stiff substrates has been coined as durotaxis and implicated in development, wound healing, and cancer, where complex interplays between immune and non-immune cells are present. Compared to the emerging mechanisms underlying the strongly adhesive mesenchymal durotaxis, little is known about whether immune cells - migrating in amoeboid mode - could follow mechanical cues. Here, we develop an imaging-based confined migration device with a stiffness gradient. By tracking live cell trajectory and analyzing the directionality of T cells and neutrophils, we observe that amoeboid cells can durotax. We further delineate the underlying mechanism to involve non-muscle myosin IIA (NMIIA) polarization towards the soft-matrix-side but may not require differential actin flow up- or down-stiffness gradient. Using the protista Dictyostelium, we demonstrate the evolutionary conservation of amoeboid durotaxis. Finally, these experimental phenomena are theoretically captured by an active gel model capable of mechanosensing. Collectively, these results may shed new lights on immune surveillance and recently identified confined migration of cancer cells, within the mechanically inhomogeneous tumor microenvironment or the inflamed fibrotic tissues.
CCDC113 stabilizes sperm axoneme and head-tail coupling apparatus to ensure male fertility
Authors: Wu Bingbing , Long Chenghong , Yang Yuzhuo , Zhang Zhe , Ma Shuang , Ma Yanjie , Wei Huafang , Li Jinghe , Jiang Hui , Li Wei , Liu Chao
Published: December 2024

The structural integrity of the sperm is crucial for male fertility, defects in sperm head-tail linkage and flagellar axoneme are associated with acephalic spermatozoa syndrome (ASS) and the multiple morphological abnormalities of the sperm flagella (MMAF). Notably, impaired head-tail coupling apparatus (HTCA) often accompanies defects in the flagellum structure, however, the molecular mechanisms underlying this phenomenon remain elusive. Here, we identified an evolutionarily conserved coiled-coil domain-containing (CCDC) protein, CCDC113, and found the disruption of CCDC113 produced spermatozoa with disorganized sperm flagella and HTCA, which caused male infertility. Further analysis revealed that CCDC113 could bind to CFAP57 and CFAP91, and function as an adaptor protein for the connection of radial spokes, nexin-dynein regulatory complex (N-DRC), and doublet microtubules (DMTs) in the sperm axoneme. Moreover, CCDC113 was identified as a structural component of HTCA, collaborating with SUN5 and CENTLEIN to connect sperm head to tail during spermiogenesis. Together, our studies reveal that CCDC113 serve as a critical hub for sperm axoneme and HTCA stabilization in mice, providing insights into the potential pathogenesis of infertility associated with human CCDC113 mutations.
Stirring up the muck: the systematics of soft-sediment Fionidae (Nudibranchia: Aeolidina) from the tropical Indo-Pacific
Authors: Kim Ashley Y. , Donohoo Samantha A. , Gosliner Terrence M.
Published: December 2024

The tropical Indo-Pacific aeolid nudibranchs of the Fionidae are poorly known and have not been studied in a concerted manner. Many undescribed species are found throughout the Indian and Pacific Oceans and are concentrated in the Coral Triangle. With the recent publication of a revised systematic arrangement of the Fionidae, documentation and description of new taxa of Fionidae is especially warranted. Here we describe Tenellia bughaw Kim & Gosliner sp. nov., Tenellia puti Kim & Gosliner sp. nov., Tenellia nakapila Kim & Gosliner sp. nov., Abronica payaso Kim & Gosliner, sp. nov. and Abronica turon Gosliner & Kim sp. nov. from the waters of the Coral Triangle. Their phylogenetic placement in Fionidae is reviewed using three genes: cytochrome oxidase I (COI), 16s rRNA, and histone 3 (H3) in a Bayesian and maximum likelihood framework. A redescription of Tenellia yamasui (Hamatani, 1993) is also provided to clarify its distinctiveness from T. bughaw and T. puti. This study confirms that all four known species of Abronica are characterized by having an acutely pointed curved penial stylet, thus confirming a unique morphological synapomorphy for members of this genus. A discussion on conflicts in the classification of fionid aeolid nudibranchs addresses concerns with extreme splitting based on novel innovations that emphasize evolutionary novelty over phyletic kinship. Instead, a more conservative approach is suggested, especially within the context of taxa that still have much undocumented primary diversity.
Adiposity and body fat distribution based on skinfold thicknesses and body circumferences in Czech preschool children, secular changes
Authors: Vážná Anna , Novák Jan M. , Daniš Robert , Sedlak Petr
Published: December 2024

Background

The long-standing widespread prevalence of obesity includes issues of its evaluation. Nutritional status may be assessed using various tools and methods; among others simple anthropometric measurements are well established. Widely used body mass index (BMI), presents an obstacle of needing to calculate a standard deviation score (SD) for correct use in the child population. As BMI overlooks body composition, it is necessary to evaluate fat and muscle mass with different methods. Established skinfolds and circumferences are used in many variations and equations to accomplish that goal; however, the parameters used in these methods also undergo secular changes. Furthermore, secular changes have been documented in fat mass distribution. The aim of the study is to assess secular changes of skinfolds thickness and body circumferences and evaluate their validity for use in clinical practice and population research.

Methods and sample

Our database consisted of a recent (2016–2022) sample with 594 participants (298 males) and a reference sample (from 1990) with 2,910 participants (1,207 males). Both cohorts comprised Czech preschool children, aged 4.00 to 6.99 years. With standard methodology, anthropometric parameters were obtained for 13 skinfolds and eight circumferences, by trained staff. The equations of Slaughter, Durnin and Deurenberg were correspondingly calculated. Statistical evaluation was conducted in the R programming language, using Welch’s test, Cohen’s d and the Bland–Altman method.

Results

Our study found significant increases in skinfold thickness on the abdomen, chest I. and forearm, with high clinical relevance (p ≥ 0.01; d = range from 0.20 to 0.70). Contrastingly, apart from the abdominal area, a decrease of circumferences was observed. The body fat percentage estimation equations were tested for bias in the recent sample in the context of bioimpedance analysis with the Bland–Altman method. All equations are suitable for application in clinical use.

Discussion

Documented secular changes in fat mass distribution are only part of a contemporary accelerating trend of obesity prevalence. Our findings support the trend of a decline of circumferences and rise of skinfold thickness in corresponding areas, especially on the limbs, that is evidenced by the trend of latent obesity. The results of the study show the need to complement established diagnostic procedures in childhood obesitology with abdominal and midthigh circumferences and optionally even the maximal circumference of the forearm. These circumferences should always be measured alongside the skinfold thickness of the region. Only in this way can the overall adiposity of an individual with regard to secular changes, including the detection of latent obesity, be objectively evaluated.
Espacialização da probabilidade de ocorrência de veranicos extremos em regiões de Minas Gerais: uma abordagem bayesiana
Authors: Reis Claudiana Goulart dos , Beijo Luiz Alberto , Butturi-Gomes Davi
Published: December 2024

O presente trabalho tem como objetivo principal espacializar a probabilidade de ocorrência de veranicos máximos para as estações chuvosa e seca em diferentes regiões de Minas Gerais via inferência Bayesiana, comparando-se diferentes estruturas de distribuição a priori para o ajuste da distribuição Generalizada de Valores Extremos (GEV) aos conjuntos de dados de veranico máximo anual. Para obtenção das marginais das distribuições a posteriori, foi aplicado o método Monte Carlo via Cadeia de Markov por meio do software R e do freeware OpenBugs. Posteriormente, foi aplicada a estrutura de priori mais eficiente para calcular a probabilidade de ocorrência de veranicos extremos para diferentes níveis de retorno e, assim, construir mapas a partir da espacialização. Foi observado que a incorporação de informação a priori fundamentados aos dados de Belo Horizonte ou Lavras permitiu que melhores resultados fossem obtidos na análise de veranicos máximos na maioria dos municípios analisados. Os valores mais expressivos de probabilidade de ocorrência de veranicos máximos na estação seca ocorreram predominantemente na porção próxima ao limite entre as mesorregiões Central Mineira e Metropolitana de Belo Horizonte, enquanto para a estação chuvosa os maiores valores de probabilidade ficaram concentrados nas regiões Campo das Vertentes, Metropolitana de Belo Horizonte e Sul/Sudoeste de Minas. A região com maior vulnerabilidade para a produção agrícola em função da ocorrência de veranicos com duração acima de 70 dias sem uma precipitação superior 5 mm na estação seca está localizada junto aos municípios de Bom Despacho, Curvelo e Sete Lagoas.