bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of Spectral-Domain Optical Coherence Tomography Findings with Visual Outcome of Macula-Off Rhegmatogenous Retinal Detachment Surgery
Authors: Kang Hae Min , Lee Sung Chul , Lee Christopher Seungkyu
Published: May 2015

Purpose: To identify prognostic factors for the visual outcome for patients with macula-off rhegmatogenous retinal detachment (RRD). Methods: The medical records of 27 patients (27 eyes) with macula-off RRD were retrospectively investigated. In addition to clinical characteristics, spectral-domain optical coherence tomography (SD OCT) images were analyzed. Results: The central foveal thickness at baseline was 923 ± 499.5 µm, and the mean height of the subretinal fluid was 697.8 ± 463.6 µm. Dropout of backreflection at the fovea was detected on preoperative SD OCT in 8 patients (29.6%). The external limiting membrane was disrupted in 5 patients (18.5%) as was the photoreceptor integrity in 9 patients (33.3%) at 12 months. On multiple regression analysis, backreflection integrity was the only predictive factor for postoperative visual outcome (B = 0.179, p = 0.020). Conclusions: Backreflection integrity on preoperative SD OCT seems to be helpful in predicting the postoperative visual outcome in macula-off RRD patients.
A Case of Complete Adult-Onset Kawasaki Disease: A Review of Pathogenesis and Classification
Authors: Drago Francesco , Javor Sanja , Ciccarese Giulia , Cozzani Emanuele , Parodi Aurora
Published: May 2015

Kawasaki disease (KD) is an acute systemic vasculitis that occurs primarily in children and rarely in adults, possibly after bacterial or viral infections in genetically susceptible hosts. KD may frequently be undiagnosed especially in adult patients without the presence of all the classical clinical criteria (incomplete or atypical KD). In addition, many differential diagnoses could be considered. Here, we report a case of KD in an adult patient with clinical features characteristic of the classical form. KD requires a long-term management in both paediatric and adult patients, in order to avoid complications that could follow both the acute and retrospective diagnoses of KD.
Molecular Analysis of the B Microchromosome in Steindachnerina insculpta (Characiformes: Curimatidae) by Microdissection
Authors: Sampaio Tatiane R. , Gouveia Juceli G. , da Silva Carlos R.M. , Dias Ana L. , da Rosa Renata
Published: May 2015

B chromosomes are additional elements to standard karyotypes observed in different species of fishes, especially in Curimatidae. However, despite studies demonstrating the occurrence of Bs, little is known about their origin and evolution. To better understand the genomic composition and evolutionary processes involving B chromosomes, microdissection of B microchromosomes in Steindachnerina insculpta was conducted. Chromosome painting revealed the totally hybridized B and markings on A chromosomes both in S. in sculpta and in Cyphocharax spilotus, demonstrating a strong homology between these different species. In specimens of C. modestus, which do not have Bs, the signals were observed on A chromosomes. Cloning and sequencing of some B fragments revealed that the B microchromosome in S. insculpta is composed of repetitive elements, homologous to the DIRS-4 LTR retrotransposon of Xenopus (Silurana) tropicalis. FISH with clone pSi48 with the DIRS-4 retroelement revealed signals on all A chromosomes in the 2 species and also on the B, suggesting the insertion of repetitive elements in these species.
Historical Evolution of the Frontal Lobe Syndrome
Authors: Krudop Welmoed A. , Pijnenburg Yolande A.L.
Published: May 2015

The function of the frontal lobes and the related frontal lobe syndrome have not been described in detail until relatively late in history. Slowly, the combination of knowledge from animal models, the detailed examination of symptoms after traumatic frontal lobe injuries, and the rise and fall of psychosurgery has led to increasing insight into frontal lobe function. The frontosubcortical circuits have been described and increasingly related to clinical syndromes, confirmed by the latest developments in functional connectivity networks.
Association of Macrophage Migration Inhibitory Factor Polymorphisms with Gestational Diabetes Mellitus in Han Chinese Women
Authors: Li Chao , Qiao Binglong , Qi Weihong , Zhan Ying , Ma Chunling , Zhao Lei , Li Guiyu
Published: May 2015

Objective: The purpose of the study was to investigate the association between macrophage migration inhibitory factor (MIF) gene polymorphisms and gestational diabetes mellitus (GDM) in Han Chinese women. Methods: In this study, 915 unrelated pregnant women were recruited, among whom 430 had GDM and 485 served as controls. The rs755622 in the MIF gene (MIF-173G/C) was detected by the polymerase chain reaction Tm-shift genotyping method with fluorescence melting curve analysis. The associations of rs755622 in MIF variants with plasma glucose and insulin levels in the oral glucose tolerance test (OGTT) as well as with with blood fat levels were investigated. Results: The frequencies of genotypes and allele types of rs755622 in MIF were significantly different between women of the GDM and control groups (all p < 0.001). Moreover, the single nucleotide polymorphism (SNP) was significantly associated with increased glucose levels at 0, 60 and 120 min during the OGTT (all p < 0.0038) and with the increased homeostasis model assessment of insulin resistance (p < 0.001) in the GDM group. Conclusion: Genetic polymorphism of rs755622 in MIF is associated with increased risk of GDM and insulin resistance in Han Chinese women.
Towards the Critical Edition of the Rutbat al-ḥakīm: A Few Preliminary Observations
Authors: de Callataÿ Godefroid , Moureau Sébastien
Published: May 2015

This article is focused on the manuscript tradition of the Rutbat al-ḥakīm, an alchemical treatise written in al-Andalus by Maslama b. Qāsim al-Qurṭubī in 339/950-342/953. The authors also describe new manuscripts of the work, including one among the earliest in the tradition of the Rutba, remained unknown until now. At the end of the article, new elements are provided about the dating of the Rutba as found in manuscripts.
The genus Luticola D.G.Mann (Bacillariophyta) from the McMurdo Sound Region, Antarctica, with the description of four new species
Authors: Kohler Tyler J , KOPALOVÁ KATEŘINA , VAN DE VIJVER BART , PATRICK KOCIOLEK J.
Published: May 2015

A revision of the freshwater diatom genus Luticola from the McMurdo Sound Region, including the McMurdo Dry Valleys and Cape Royds, Antarctica, was made to contribute to a consistent flora for the entire Antarctic Region. Detailed light and scanning electron microscopic observations, review of pertinent literature, and examination of historical and type material lead to the identification of 12 Luticola species. Four new species and one new combination are proposed, including L. bradyi sp. nov., L. spainiae, sp. nov., L. macknightiae, sp. nov., L. transantarctica, sp. nov., and L. elegans, comb. nov. stat. nov. Several of these taxa were previously identified as part of the L. muticopsis (Van Heurck) D.G.Mann complex; Navicula muticopsis f. evoluta W. & G.S. West, L. muticopsis f. reducta (W. & G.S. West) Spaulding, and N. muticopsis f. capitata Carlson, or mistaken for the similar L. mutica (Kützing) D.G.Mann and L. cohnii (Hilse) D.G.Mann. Morphological features of all new species were compared to the closest morphologically similar taxa, and their ecology and biogeography are discussed. All Luticola species considered here show restricted Antarctic distributions, and 8 of the 12 reported species are known only from the Antarctic continent.
First occurrence of Gracilaria chilensis, and distribution of Gracilariopsis lemaneiformis (Gracilariaceae, Gracilariales) in Peru on the basis of rbcL sequence analysis
Authors: Arakaki Natalia , SCHMIDT WILLIAM E. , CARBAJAL PATRICIA , FREDERICQ SUZANNE
Published: May 2015

The terete taxa Gracilariopsis (hereafter Gp.) lemaneiformis (Bory) Dawson, Acleto & Foldvik and Gracilaria (hereafter G.) chilensis Bird, McLachlan & Oliveira resemble each other in branching pattern. This study aims to analyze samples attributed to G. chilensis from a southern locality in Peru using molecular tools, in order to differentiate it from Gp. lemaneiformis samples collected along the Peruvian coast. Species identification of the Gracilariaceae, especially of the terete forms, is notoriously difficult due to morphological plasticity and convergence of their thalli, and the correct taxonomic identification of non-reproductive, cylindrical specimens remains a difficult task (Gurgel & Fredericq 2004). Utilizing traditional morphometric techniques, Edding et al. (2006) concluded that G. chilensis, comprising a single morphotype, is the main species of Gracilaria present along the Chilean coast, in which natural populations are distributed between 30°S and 45°S, from Coquimbo to Southern Chiloe (Bird et al. 1986), with farms extending further north to Antofagasta (24°S) (Santelices & Ugarte 1990). Hoffmann & Santelices (1997) found the establishment of G. chilensis on the coast of Coihaique (45°S) mainly due to aquaculture introduction. This species also occurs in the western Pacific Ocean, ranging from southeastern Australia to New Zealand (Nelson 1987). Gracilariopsis Dawson was long merged into Gracilaria until Fredericq & Hommersand (1989) resurrected Gracilariopsis on the basis of lack of nutritive cells in the cystocarp, and with chorda-type surface spermatangia. Gp. lemaneiformis has a geographical range from Paita, Peru to Antofagasta in northern Chile (Ramírez & Tapia 1991). DNA sequence analysis has been the most reliable and widely used molecular technique to infer phylogenic relationships at the species level within the Gracilariaceae (Gurgel & Fredericq 2004), and recognition of Gracilariopsis as a genus distinct from Gracilaria received strong support from the molecular studies of Bird et al. (1994), and Gurgel et al. (2003), among others. According to Gurgel et al. (2003), Gp. lemaneiformis is shown not to have a worldwide distribution but to be restricted to the vicinity of Peru, whereas the species going under the name Gp. “lemaneiformis” from North and South Carolina is now referred to as Gp. carolinensis Liao et Hommersand, and Gp. “lemaneiformis” from China and Japan constitutes an undescribed species that is related to Gp. heteroclada Zhang et Xia.
Editorial Essay
Authors: Davis Gerald F.
Published: May 2015

Organizational research is guided by standards of what journals will publish and what gets rewarded in scholarly careers. This system can promote novelty rather than truth and impact rather than coherence. The advent of big data, combined with our current system of scholarly career incentives, is likely to yield a high volume of novel papers with sophisticated econometrics and no obvious prospect of cumulative knowledge development. Moreover, changes in the world of organizations are not being met with changes in how and for whom organizational research is done. It is time for a dialogue on who and what organizational research is for and how that should shape our practice.
Ego-Oriented Preaching
Authors: Dearing Richard N.
Published: May 2015

Ego-oriented and superego-oriented preaching styles are strikingly different in their methodology and in their understanding of human motivation. Long-term, constructive results are the product of ego-oriented preaching while superego-oriented preaching yields quick but ineffective results. The objective of ego-oriented preaching is the formation of an identity in which persons know themselves loved in spite of their faults and in which they use their abilities productively within the world as it is given.
An Experimental Course for Clergymen in Suicidodolgy and Crisis Intervention
Authors: Strunk Orlo , Jordan Merle R.
Published: May 2015

A pilot course in suicidology for clergymen is described and evaluated. Various instruments designed to evaluate curricular and instructional modes yielded essentially positive results. It is suggested that a course in suicidology and self-destructive behavior might well be a viable and significant aspect of a clinical pastoral education quarter, a summer institute, a continuing education experience, as well as a course in a theological seminary. The strength of this kind of course rests especially in the utilization of a variety of instructional modes and a wide range of resources, personal and community.
Death and Dying: A Psychoanalytic Perspective
Authors: Benson George
Published: May 2015

Modern man does not view death as a natural phenomenon, but as an enemy to be conquered or a reality to be denied. Freud's understanding of death, however, reestablishes death as a natural phenomenon rather than an artificial catastrophe. Death as it is usually experienced is not frightening. It is the inescapably personal opportunity for growth which death thrusts upon one that is terrifying because growth involves loss. The decision open to man in death is to affirm or deny that death is beyond righteousness, retribution, and understanding. When all of these things are given up, then death is man's first and last chance to embrace the utter humanness of his condition.
The Parent–Young Adult Conference as a Diagnostic Tool
Authors: Cox Richard H.
Published: May 2015

A psychologist in collaboration with a psychiatrist utilizes a joint parent—young adult conference as a tool for diagnosis and suggesting treatment. The two professionals allow the youth to set the stage for explaining his problem to his parents and employ observation, interpretation, and support as a means of finding an appropriate treatment plan and motivating the family members toward getting help.
Intentionality and the Ministry
Authors: Mills Edgar W.
Published: May 2015

Intentionality is one basic work style among ministers today, and it can be fruitfully cultivated. Intentional ministry involves three levels: intentions such as planning, setting priorities, creating one's role and mobilizing resources; vocation as a sense of an underlying direction, movement and meaning in one's life; and the shared consciousness of the possibility of change, taking the form of collaborative problem-solving. The central issue is to define areas of initiative consistent with one's vocation and to enter into supportive relationships and shared effort which will broaden and strengthen the intentional base of one's ministry.
Innocents Aboard: Clinical Training in the Early Days
Authors: French Porter
Published: May 2015

Clinical training in 1932 was an exposure to the primary living material of theology. The rationale for the program was that students, enabled to observe and empathize with patients at the acute level of pathological behavior, would be able to recognize the same problems in the “normal” state in the parish; and, in the process, become more mature and helpful themselves.
Law and Gospel in Pastoral Care
Authors: Hunter Rodney J.
Published: May 2015

A concern for the demands of the Law and for the message of the forgiveness of sins does not characterize the way most modern, progressive, clinically educated pastors tend to view or practice their ministry with troubled persons. But if our pastoral care is to become more fully responsive and responsible to our theological heritage, and more profoundly related in a Christian way to the persons we serve, it will be necessary to recover the centrality of the doctrine of Law and Gospel in pastoral care and counseling. This article attempts to show why and how it might be done.
An Exploration into the Reasons People Choose a Pastoral Counselor Instead of Another Type of Psychotherapist
Authors: Posavac Emil J. , Hartung Bruce M.
Published: May 2015

The results of several approaches to understanding the laymen's perception of fulltime pastoral counselors are reported. No striking differences among the respondents' views of various types of psychotherapists were found. However, 20% of the clients of a pastoral counseling center gave clear religious reasons for choosing the center rather than seeking help from another source of therapy. Also important was the finding that the rate of clergy referrals to the center (about half of all clients) is far in excess of published clergy referral rates to psychiatrists, psychologists or psychoanalysts. The importance of ties between pastoral counseling centers and community parishes is stressed.
The Impact of the Seminary Experience on the Marital Relationship
Authors: Brightman Lloyd A. , Malette Theodore A.
Published: May 2015

A sample of married seminarians and their wives was surveyed at a northeastern seminary where individuals were going into the ministry as a second career. The survey focuses on perceived changes in the marital relationsip as a result of the seminary experience and suggests the need for future research.
A Ceremony for the Divorced
Authors: Norman Sam R.
Published: May 2015

There is a religious ritual or ceremony for every other crisis of life; marriage, birth, and death. This author is suggesting that the church needs to recognize and give support to those persons going through the crisis of divorce. One way the church can do this is to offer a ceremony of divorce—a ceremony that acknowledges the need to express the feelings of anger, guilt, grief, acceptance and forgiveness.
Effects of Authentication Method and System Properties on Authentication Decisions and Performance
Authors: Nehmadi Liron , Meyer Joachim
Published: May 2015

Knowledge-based authentication is the oldest and most widely used form of authentication, but it is still problematic. We present a model of the effects of usage cost variables (e.g., code length, required motion precisions) on authentication performance (time for authentication, error rate) and on the decision to use authentication. We tested model predictions in two experiments in which participants played an investment game and had to use authentication to change their investment. We manipulated the authentication method (personal identification number vs. graphical password), the required precision for authentication, the code length, and time pressure. The variables affected authentication decisions and performance, but the effects were not the same. Also, when the graphical password required greater response precision, performance and subjective ratings decreased dramatically, much more than predicted by combining the effects of the variables independently. These results point to a number of issues that must be considered when designing authentication procedures.
One Century of Global IQ Gains
Authors: Pietschnig Jakob , Voracek Martin
Published: May 2015

The Flynn effect (rising intelligence test performance in the general population over time and generations) varies enigmatically across countries and intelligence domains; its substantive meaning and causes remain elusive. This first formal meta-analysis on the topic revealed worldwide IQ gains across more than one century (1909–2013), based on 271 independent samples, totaling almost 4 million participants, from 31 countries. Key findings include that IQ gains vary according to domain (estimated 0.41, 0.30, 0.28, and 0.21 IQ points annually for fluid, spatial, full-scale, and crystallized IQ test performance, respectively), are stronger for adults than children, and have decreased in more recent decades. Altogether, these findings narrow down proposed theories and candidate factors presumably accounting for the Flynn effect. Factors associated with life history speed seem mainly responsible for the Flynn effect’s general trajectory, whereas favorable social multiplier effects and effects related to economic prosperity appear to be responsible for observed differences of the Flynn effect across intelligence domains.
Formation mechanism of coarse grained zone in annealed high Nb–TiAl–xB ingots
Authors: Zhang Z. Y. , Xu X. J. , Liang Y. F. , Zhang L. Q. , Lin J. P.
Published: May 2015

High Nb–TiAl ingots with various boron levels (0, 0.2, 0.5, 0.7 and 1.0 at-) were investigated using annealing in a single α phase field for various lengths of time, and a coarse grained zone (CGZ) was observed when the boron content was greater than 0.5 at-. Scanning electron microscopy and transmission electron microscopy were used to study microstructural evolution and boride transformation. Experimental results show that the width of CGZ is closely related with the boron addition and the cooling rate. The formation mechanism is discussed for various nucleation behaviors of boride at the ingot scale during solidification caused by the temperature induced supercooling and the boron induced compositional supercooling, which lead to dissimilar pinning effects of borides at high temperature.
Heat transfer coefficient evolution of boron steel during hot forming die quenching
Authors: Gu Z.-W. , Lv M.-M. , Lu G.-H. , Xu H. , Li X.
Published: May 2015

Based on a novel calculation model that considers microstructural changes and latent heat release, evolution of heat transfer coefficients of boron steel in different metallographic states during hot forming die quenching are investigated. Results demonstrate that the evolution of the coefficients in the different metallographic states is significantly different in each state. As blank temperature decreases, no evident fluctuations emerge in the austenitic state, a significant sharp increase followed by a gradual decrease is detected in the multiphase state during martensitic transformation and a slight decrease is observed in the martensitic state. A simulation model for temperature predicting is established by integrating the coefficient data with the finite element software ABAQUS. The numerical results showed good agreement with the experimental results.
Kinetic analysis of direct current field enhanced salt bath nitriding
Authors: Zhou Z. S. , Hu J.
Published: May 2015

A novel rapid salt bath nitriding technology based on normal salt bath nitriding was primarily developed by additionally applying a direct current field (DCF) of 7·5 V between the treated samples, and the corresponding kinetics was investigated. The results showed that DCF could significantly enhance the nitriding efficiency, shorten the holding duration and decrease the treatment temperature. Meanwhile, the diffusion coefficient of nitrogen was increased about two times, and the activation energy was decreased from 184 to 159 kJ mol− 1. The main enhancement mechanism was discussed as well.
Intracranial hemorrhage in patients with brain metastases treated with therapeutic enoxaparin: a matched cohort study
Authors: Donato Jessica , Campigotto Federico , Uhlmann Erik J. , Coletti Erika , Neuberg Donna , Weber Griffin M. , Zwicker Jeffrey I.
Published: May 2015

Key Points

Significant intracranial hemorrhage occurs in 20% to 50% of patients with metastatic brain tumors. Therapeutic anticoagulation in patients with brain metastasis did not increase the risk for intracranial hemorrhage.
RETRACTED ARTICLE: Protective role of p120-catenin in maintaining the integrity of adherens and tight junctions in ventilator-induced lung injury
Authors: Gu Changping , Liu Mengjie , Zhao Tao , Wang Dong , Wang Yuelan
Published: May 2015

Background

Ventilator-induced lung injury (VILI) is one of the most common complications for patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). Although p120 is an important protein in the regulation of cell junctions, further mechanisms should be explored for prevention and treatment of VILI.

Methods

Mouse lung epithelial cells (MLE-12), which were transfected with p120 small interfering (si)RNA, p120 cDNA, wild-type E-cadherin juxtamembrane domain or a K83R mutant juxtamembrane domain (K83R-JMD), were subjected to 20 % cyclic stretches for 2 or 4 h. Furthermore, MLE-12 cells and mice, which were pretreated with the c-Src inhibitor PP2 or RhoA inhibitor Y27632, underwent 20 % cyclic stretches or mechanical stretching, respectively. Moreover, wild-type C57BL/6 mice were transfected with p120 siRNA-liposome complexes before mechanical ventilation. Cell lysates and lung tissues were then analyzed to detect lung injury.

Results

cyclic stretches of 20 % actived c-Src, which induced degradation of E-cadherin, p120 and occludin. However, loss of p120 increased the degradation and endocytosis of E-cadherin. Immunoprecipitation and Immunofluorescence results showed a decrease in the association between p120 and E-cadherin, while gap formation increased in p120 siRNA and K83R-JMD groups after 20 % cyclic stretches. Loss of p120 also reduced the occludin level and decreased the association of occludin and ZO-1 by enhancing RhoA activity. However, the altered levels of occludin and E-cadherin were reversed by PP2 or Y27632 treatments compared with the cyclic stretch group. Consistently, the expression, redistribution and disassociation of junction proteins were all restored in the p120 overexpression group after 20 % cyclic stretches. Moreover, the role of p120 in VILI was confirmed by increased wet/dry weigh ratio and enhanced production of cytokines (tumor necrosis factor-α and interleukin-six) in p120-depleted mice under mechanical ventilation.

Conclusions

p120 protected against VILI by regulating both adherens and tight junctions. p120 inhibited E-cadherin endocytosis by increasing the association between p120 and juxtamembrane domain of E-cadherin. Furthermore, p120 reduced the degradation of occludin by inhibiting RhoA activity. These findings illustrated further mechanisms of p120 in the prevention of VILI, especially for patients with ALI or ARDS.
Partial protein domains: evolutionary insights and bioinformatics challenges
Authors: Kelley Lawrence A , Sternberg Michael JE
Published: May 2015

Protein domains are generally thought to correspond to units of evolution. New research raises questions about how such domains are defined with bioinformatics tools and sheds light on how evolution has enabled partial domains to be viable.
Non-steroidal anti-inflammatory drugs and their benefits and harms: the challenge of interpreting meta-analyses and observational data sets when balanced data are not analyzed and reported
Authors: Simon Lee S.
Published: May 2015

A multitude of reports have delineated the risks of using non-steroidal anti-inflammatory drugs but have not been totally congruent. Meta-analyses of randomized controlled trials sometimes concur regarding gastrointestinal risk and cardiovascular risk but rarely report a balance of these risks for any one drug. Benefits measured in these studies are usually not reported. Observational data sets, supposedly reflective of ‘real world’ patients, do not always agree with the randomized controlled trial reports. Clinicians need assessments measuring the balance of harms and benefits so that better decisions based on their patients’ unique risk factors can be reached.
On the capacity of MIMO correlated Nakagami- m fading channels using copula
Authors: Gholizadeh Mohammad Hossein , Amindavar Hamidreza , Ritcey James A
Published: May 2015

In this paper, a novel approach is proposed based on the probability density function (PDF) concept to achieve the capacity of a correlated ergodic multi-input multi-output (MIMO) channel with Nakagami-m fading. In our proposed method, channel parameters are unknown, and they are initially estimated by using the PDF of the received samples in the receiving antennas. The copula theory is employed to estimate the parameters of the channel in the proposed PDF-based approach. By appealing to copula, the notion of PDF estimation is simplified in the computation technique when we are faced with correlated signals. Since we are working on a correlated channel, the copula concept results in a powerful estimation approach for the PDF of the signals in the receivers. Accurate PDF estimation leads to having a precise calculation for channel parameters. Hence, the new approach guarantees that the capacity of a correlated ergodic channel is predicted reliably. In the previous works, either the capacity of simple uncorrelated Nakagami-m channels is presented or an asymptotic formulation is suggested for a correlated Nakagami-m channel. However, our proposed method introduces an analytic expression for the capacity of the MIMO correlated Nakagami-m fading channel relying on copula. All the results in both channel parameter estimation and channel capacity prediction are validated with some simulations.
Regions-based two dimensional continua: The Euclidean case
Authors: Hellman Geoffrey , Shapiro Stewart
Published: May 2015

We extend the work presented in [7, 8] to a regions-based, two-dimensional, Euclidean theory. The goal is to recover the classical continuum on a point-free basis. We first derive the Archimedean property for a class of readily postulated orientations of certain special regions, “generalized quadrilaterals” (intended as parallelograms), by which we cover the entire space. Then we generalize this to arbitrary orientations, and then establishing an isomorphism between the space and the usual point-based R × R. As in the one-dimensional case, this is done on the basis of axioms which contain no explicit “extremal clause” (to the effect that “these are the only ways of generating regions”), and we have no axiom of induction other than ordinary numerical (mathematical) induction. Finally, having explicitly defined ‘point’ and ‘line’, we will derive the characteristic Parallel’s Postulate (Playfair axiom) from regions-based axioms, and point the way toward deriving key Euclidean metrical properties.
Colocation Still Matters: Conformance Quality and the Interdependence of R&D and Manufacturing in the Pharmaceutical Industry
Authors: Gray John V. , Siemsen Enno , Vasudeva Gurneeta
Published: May 2015

This study investigates the conformance quality benefits of colocating manufacturing with research and development (R&D) activities. Findings from a panel data set of U.S.-based pharmaceutical plants over a 13-year period reveal that colocation of manufacturing and R&D relates to better conformance quality, on average, across the entire sample. We find that these benefits of colocation persist throughout the time period we study (1994–2007), which is surprising, given the rapid development of information and communication technologies during that time. These benefits are particularly enhanced for manufacturing plants operating with processes that involve a high level of tacit process knowledge and that belong to large firms. Our findings highlight the importance of matching organizational design with process and firm characteristics in settings involving knowledge interdependence. They also highlight the continued value of physical proximity through geographical colocation between manufacturing and R&D activities to achieve desired quality outcomes.

This paper was accepted by Serguei Netessine, operations management.
Effects of ions traces on the dissolution of bioceramics composed of hydroxyapatite and Î²-tricalcium phosphate
Authors: Jamil Mohamed , Abida Fatima , Hatim Zineb , Elassfouri Mostafa , Gourri Elhassan
Published: May 2015

The aim of this work is to study the effect of trace ions as Mg2+, Sr2+, (SiO4)4- and Al3+, brought by the raw material, on the dissolution of the calcium-phosphate bioceramics. Â The precursor powders prepared by aqueous precipitation with molar ratio Ca / P = 1.630 Â± 0.002, were calcined at 1100Â°C resulting in the formation of a mixture of hydroxyapatite (Ca10(PO4)6(OH)2) and Î²-tricalcium phosphate (Î²-Ca3(PO4)2). Â Two mixtures which differ by the content of trace ions were characterized for phase purity, chemical composition and morphology. Â The dissolution tests were performed at 37 Â°C in acidic buffers solution at pH 4.8. Â The results showed that the dissolution of calcium ions is more important in the presence of ions trace while the phosphor ions were not affected. Â The dissolution and dissolution-reprecipitation observed of various ions trace can modify the surface properties of calcium phosphate bioceramics and therefore the properties of biological products, such as resorbtion and reactivity can be affected.
Biosorption of Copper (Cu 2+) in aqueous solution by an adsorbent materiel prepared from marine algae (Bifurcaria bifurcata): Equilibrium and kinetic studies
Authors: Khamliche Layachi , Bakkas Salem , Benzidia Nawal , Salhi Anas
Published: May 2015

Morocco is a country influenced by the 3500 km of coastline, with the presence of many marine species. Among these species, there is a wide variety of marine algae that have been specifically used in pharmacological studies, but also environmental. Among these seaweed species Bifurcaria bifurcata having a very large biomass was used as a novel adsorbent for the removal of copper in aqueous solution. Adsorption tests showed that the equilibrium is established after 60 minutes. Various experimental parameters were analyzed: pH, adsorbent mass and initial concentration of copper. Experimental results have shown that the adsorption of copper on seaweed pH dependent of the solution and the initial concentration of copper.The adsorption capacity was determined using the Langmuir and Freundlich isotherms. The maximum adsorption capacity is 101.9 mg.g-1. The kinetic study of the adsorption of copper on the algae showed that the adsorption process follows the pseudo-second order kinetic model with high R2 values.Â Â
New substituted indene derivatives from bicyclic Baylis-Hillman acetate
Authors: AMRI Hassen
Published: May 2015

A convenient protocol for the synthesis of highly functionalized indenes 4 has been developed. The coupling reaction of bicyclic Baylis-Hillman acetate 2 with nitroalkane salts in basic conditions led to the corresponding substituted indenes in good yields and high purity.
Corrosion Inhibition of AISI 316L and Modified-AISI 630 Stainless Steel by the New Organic Inhibitor [(CH3)2N]3PSe in Chloride Media:Electrochemical and Physical Study
Authors: ZARGOUNI Yafa , SASSI Wafa , ALOUANI Khaled
Published: May 2015

We evaluate the effect of the Tris-dimethylaminoselenophosphoramide (SeAP)on the corrosion inhibition of modified-AISI 630 and AISI 316L stainless steel (SS) in 3 wt. % NaCl. The electrochemical behaviors of tested SS samples are investigated before and after adding the Seep into the chloride media by potentiodynamic polarization technique. The adsorption of SeAP onto both SS surfaces is verified by global discharge optical emission spectroscopy (GDOES).Â  SeAP is found to be a good inhibitor for SS corrosion, especially when added at a concentration of 0.5 wt. %.
Application of cooling, heating loads in an autonomous microgrid as a control strategy
Authors: Vahedipour Dahraie Mostafa , Rashidizadeh Kermani Homa , Najafi Hamid Reza
Published: May 2015

In this paper, a control scheme is proposed for a microgrid. In the proposed scheme, by controlling cooling, heating loads (C/H loads), balance between generation and consumption power is kept, and the frequency remains within its nominal value. Application of storage systems imposes costs, operating and maintenance problems to the microgrid owners. Moreover, the charge and discharge process of batteries causes reduction in their lives time. The dominant concept of this scheme is to control frequency without any storage. In this case, the coincidence of generation and consumption in C/H load technology is not necessary. This control system changes the consumption power of C/H loads and responses to unbalance power of microgrid, fast. Moreover, two indices are defined to assess the performance of the microgrid.
The Art and Science of Consultations in Bovine Medicine: Use of Modified Calgary – Cambridge Guides
Authors: Petrovski Kiro R. , McArthur Michelle
Published: May 2015

This article describes few steps of the application of the modified Calgary-Cambridge Guides (CCG) to consultations in bovine medicine. A review of pertinent clinical communication skills literature in human medicine was integrated with the burgeoning research within veterinary medicine. In particular, there are more recent studies examining companion animal veterinarian’s communication skills and outcomes which can be extrapolated to practitioners. This was integrated into a teaching example of a reproductive case consultation. The first article deals with the 1) Preparation, 2) Initiating the Session and 3) Gathering Information sections. The aim of the modified CCG is to provide a set of skills to facilitate a relationship-centred approach to consultations in bovine medicine, both at the individual animal and population level. They were initially developed for human medicine and expanded recently for use in veterinary medicine. The CCG enable the practitioner to facilitate interacting with that particular client at the time of the consultation. It is likely that the majority of practitioners do use many of the skills recommended by the modified CCG. These skills are often gained through experience. However, they may not use the skills intentionally and with purpose for a specific communication goal or outcome. Practitioners can improve their communication skills using the set of skills as recommended by the modified CCG. They allow the practitioner to gain insight into the client’s understanding of the problem, including underlying aetiology, epidemiology and pathophysiology. The guides also provide opportunity to understand client’s expectations regarding the outcome, motivation and willingness to change and adherence.
Information on huchen, Hucho hucho (L.), from historical Polish sources
Authors: Cios Stanisław
Published: May 2015

This paper presents historical information on the Danube huchen, Hucho hucho (L.), in Polish sources from the sixteenth to early twentieth centuries in the Danube, Prut, Dniester, and Vistula river basins. These accounts concern the historical distribution of the species and its economic importance, culinary value, fishing methods, and artificial reproduction and propagation. The occurrence of huchen in the Dniester River basin until the beginning of the eighteenth century merits special interest, because this river is not mentioned by any modern source on the natural distribution of this species. The extinction of the huchen in this river can likely be attributed to anthropogenic changes in the environment that were associated mainly with agricultural development.
Modeling of a UASB Reactor by NARX Networks for Biogas Production
Authors: Jain Vinod , Sambi Surinder , Kumar Shashi , Kumar Brajesh , Kumar Surendra
Published: May 2015

An Artificial Neural Network model of a UASB Reactor has been developed. The reactor treats bagasse wash water (containing organics), generated after washing of stored bagasse prior to its use in paper manufacture. In the process, biogas, a renewable source of energy is produced. As the UASB reactors (2×5,000 m3 volume) operate mostly with feed having varying characteristics, therefore a special type of dynamic networks, called NARX networks have been used to model it for predicting biogas production rate. The input to the model is influent flow rate, inlet and outlet COD. Model is based upon 576 days plant data. NARX model architecture consists of input, output, and 2 hidden layers each having 10 neurons and utilizes 4 days delay. The developed ANN model represents the dynamic behavior of UASB reactor and recursively predicts and forecasts the biogas production rate with acceptable deviation with respect to actual production rate.
Optimal Dispatch of Unreliable Electric Grid-Connected Diesel Generator-Battery Power Systems
Authors: Xu D. , Kang L.
Published: May 2015

Diesel generator (DG)-battery power systems are often adopted by telecom operators, especially in semi-urban and rural areas of developing countries. Unreliable electric grids (UEG), which have frequent and lengthy outages, are peculiar to these regions. DG-UEG-battery power system is an important kind of hybrid power system. System dispatch is one of the key factors to hybrid power system integration. In this paper, the system dispatch of a DG-UEG-lead acid battery power system is studied with the UEG of relatively ample electricity in Central African Republic (CAR) and UEG of poor electricity in Congo Republic (CR). The mathematical models of the power system and the UEG are studied for completing the system operation simulation program. The net present cost (NPC) of the power system is the main evaluation index. The state of charge (SOC) set points and battery bank charging current are the optimization variables. For the UEG in CAR, the optimal dispatch solution is SOC start and stop points 0.4 and 0.5 that belong to the Micro-Cycling strategy and charging current 0.1 C. For the UEG in CR, the optimal dispatch solution is of 0.1 and 0.8 that belongs to the Cycle-Charging strategy and 0.1 C. Charging current 0.1 C is suitable for both grid scenarios compared to 0.2 C. It makes the dispatch strategy design easier in commercial practices that there are a few very good candidate dispatch solutions with system NPC values close to that of the optimal solution for both UEG scenarios in CAR and CR.
A Socio-Demographic Analysis of Responses to Terrorism
Authors: Salvatore Christopher , Rubin Gabriel
Published: May 2015

Extensive research has found that there are differences in reported levels of fear of crime and associated protective actions influenced by socio-demographic characteristics such as race and gender. Further studies, the majority of which focused on violent and property crime, have found that specific demographic characteristics influence fear of crime and protective behaviors. However, little research has focused on the influence of socio-demographic characteristics on perceptions, and protective actions in response to the threat of terrorism. Using data from the General Social Survey, this study compared individual level protective actions and perceptions of the effectiveness of protective responses to the 9/11 terrorist attacks among Americans for demographic factors that have been found to influence fear of crime and protective actions. Results indicated that several socio-demographic factors including race and gender do exhibit some differences in perceptions of the effectiveness of responses to terrorism, although not all achieved statistical significance. Results are discussed in relation to their implications for criminological theory, security, and terrorism preparedness.
Language and Hume’s Search for a Theory of the Self
Authors: Schwerin Alan
Published: May 2015

In his Treatise Hume makes a profound suggestion: philosophical problems, especially problems in metaphysics, are verbal. This view is most vigorously articulated and defended in the course of his investigation of the problem of the self, in the section “Of personal identity.” My paper is a critical exploration of Hume’s arguments for this influential thesis and an analysis of the context that informs this 1739 version of the nature of philosophical problems that anticipates the linguistic turn in philosophy.
Preparation and characterization of poly(MMA-EGDMA-AMPS) microspheres by soap-free emulsion polymerization
Authors: Xu Jingshui , Chen Denglong , Hu Xianglong , Ke Yangchuan , Zhou Qian , Gao Wensuai , Zeng Zheling , Zhang Guoliang
Published: May 2015

The poly(methyl methacrylate-ethylene glycol dimethacrylate-2-acrylamido-2-methylpropanesulfonic acid) [poly(MMA-EGDMA-AMPS)] microsphere was produced by a soap-free emulsion polymerization of MMA, EGDMA and AMPS. The chemical composition, morphology, particle size distribution and properties of the obtained microspheres were characterized by energy dispersive spectrometer (EDS), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), a laser particle analyzer and thermogravimetric analysis (TGA). Results showed that the microspheres had a high-quality spherical morphology, irrespective of the components, and their particle sizes mainly ranged from 10 μm to 70 μm. The microspheres were thermally stable up to 190°C. As the AMPS loading was increased, the synthetic yield rate decreased and the water uptake increased. The optimum synthetic yield rate and water uptake were obtained at a 2.0 wt% AMPS. In addition, the selected microspheres with a diameter of approximately 25 μm provided an effective plugging, and the plugging rate was up to 80%. This study demonstrated that the plugging behavior of microspheres was due to their deformation, migration and aggregating properties in the plugging process, which made them potential materials for modifying the porous reservoir to enhance oil recovery in petroleum engineering.
On the origin of indentation size effects and depth dependent mechanical properties of elastic polymers
Authors: Han Chung-Souk , Sanei Seyed H.R. , Alisafaei Farid
Published: May 2015

Indentation size effects have been observed in both polymers and metals but, unlike in metals, the origin of size effects in polymers is not well understood. To clarify the role of second order gradients of displacements, a model polymer is examined with spherical and Berkovich tips at probing depths between 5 and 25 μm. Applying different theories to determine the elastic modulus, it is found that with a pyramidal tip, the elastic modulus increases with decreasing indentation depth, while tests with the spherical tip yielded essentially constant values for the elastic modulus independent of indentation depth. The differences between these tips are attributed to second order displacement gradients, as they remain essentially constant with a spherical tip while they increase in magnitude with decreasing indentation depth applying a Berkovich tip.
Die aktuelle Situation der Gesundheit von Kindern und Jugendlichen
Authors: Poethko-Müller Christina , Schmitz Roma , Ellert Ute
Published: May 2015

In der Epidemiologie dienen Kriterien wie Prävalenz, Krankheitsschwere, Risikopotenzial für Folgekrankheiten im Erwachsenenalter und Chronifizierung, aber auch der individuelle und familiäre Leidensdruck der thematischen Schwerpunktsetzung in der Kinder- und Jugendgesundheitsforschung. Übergewicht und Adipositas, psychische Störungen, allergische Erkrankungen und Unfälle haben eine hohe Prävalenz im Kindes- und Jugendalter, bergen das Risiko für Folgekrankheiten und Chronifizierung (z.B. Übergewicht, Adipositas und Allergien), schränken die ungestörte Entwicklung der Kinder ein und belasten betroffene Familien (z.B. psychische Störungen, Allergien, Unfälle) und zählen deshalb in diesem Kontext zu den bedeutsamsten Themen. Nachfolgend wird ein kurzer Überblick hierzu gegeben (ausführlicher siehe Schwerpunkthefte zur KiGGS-Studie im Bundesgesundheitsblatt Heft 5/6 (2007) bzw. Heft 7 (2014)).