bluuebunny/crossref_metadata_2025 huggingface dataset:
Cloud Based Intelligent Decision Support System for Disaster Management Using Fuzzy Logic
Authors: Areej Fatima  , Sagheer Abbas  , Muahmmad Asif
Published: March 2022

Field of cloud computing is an emerging field in computer science. Computational intelligence and Decisions Supports Systems (DSS) have to gained concerns as a computing solution to planned and unplanned problems of organizations in order to progress decision-making tasks in a better way. In today era, Disaster management is a big problem. To overcome this problem, a real time computation is required. Cloud computing is a tool to offer promising support to decision support system in a real time environment. In this paper, a fuzzy based decision support system is proposed to meet all the requirements using fuzzy logic inference system.
Dengue Fever: How Aware Are We? A Qualitative Study of the Knowledge and Preventive Measures Against Dengue in Lahore
Authors: Aqsa Iftikhar
Published: March 2022

Dengue fever is an emerging contagious disease which has proved to be potentially life-threatening. It is significant to uphold good personal and environmental hygiene in order to inhibit the outbreak of such a disease. Dengue fever (DF) is a severe febrile disease which is caused by dengue virus transferred by the female Aedes mosquito. This is one of the leading causes of death in Asian countries. The natural science of dengue infections is sturdily related with human activities and habits. The paper is designed across a study which was intended to evaluate the knowledge, attitude, and practice of people regarding dengue disease in Lahore, including the urban and sub-urban regions. A suitable sample of 200 residents (of Lahore city) is considered as contributors in study. Most of the respondents had good acquaintance with the causes, indications, mode of transmission of the virus as well as precautionary measures about dengue fever. Most prevalent precautionary method was the use of coils, liquid vaporizers. Health professional and television /radio proved to be the significant sources of information for the disease. Outcomes proposed that better awareness does not essentially lead to improved practice of dengue measures. Government educational campaigns should give more importance in providing variety of information sources, skills and support to improve dengue awareness among residents.
DESIGN AND DEVELOPMENT OF ROWING BIKE TO OPTIMIZE COST
Authors:   D. Y. Patil College of Engineering, Pune,, Ingale Adesh D.
Published: March 2022

In our day-to-day life, we all have seen bikes, cycles. Some work on diesel, petrol while some work on physical efforts. Regular exercise is not possible for many people so we have innovated this row bike which is different from the other cycles. Regular Cycles help in exercising the lower side of the body but this row bike can exercise you a whole body workout. This row bike can be used by all the sportsmen who are always craving fitness. The mechanism used in this project is seen in the Gymnasium all the time, what we called it a rowing machine and the second thought is the process of rowing a boat. The action steps mentioned further continue the transmission process and drive the bike forward or transmit power to the rear wheel, we have used a coil spring to rotate the wheel, and power is transmitted. Keywords: Design, 3D Modelling, Manufacturing, Material Selection, Rowing Bike
Límites a la autotutela de la TGSS respecto de altas indebidas.
Authors: Sempere Navarro Antonio V.
Published: March 2022

La sentencia comentada considera que la Tesorería General de la Seguridad Social (TGSS) no puede anular un alta previamente aceptada. De ese acto de encuadramiento derivan diversos derechos para la persona afectada y solo es posible dejarlo sin efecto presentando una demanda ante el Juzgado de lo Social. En el caso concreto de persona extranjera que no manifiesta la ausencia de autorización para residir en España la TGSS tampoco puede anular el alta indebida pues ella era quien debía de haber solicitado y comprobado la existencia de tal requisito.
The commented sentence considers that the General Treasury of the Social Security (TGSS) cannot cancel a previously accepted registration. Various rights for the affected person derive from this framing act and it is only possible to render it without effect by filing a lawsuit before the Social Court. In the specific case of a foreign person who does not state the absence of authorization to reside in Spain, the TGSS cannot cancel the improper registration either, since she was the one who should have requested and verified the existence of such a requirement.
Derecho a la protección de datos y monitorización del trabajo: juego de incumplimientos.
Authors: Rivas Vallejo Pilar
Published: March 2022

No existe vulneración del derecho fundamental a la privacidad de los datos si se constata, a través de monitorización del trabajo, consistente en la atención telefónica, un incumplimiento reiterado, que permite conceder válidamente efectos disciplinarios a la monitorización pese a que se pactó colectivamente lo contrario, asumiendo la empresa el compromiso de no darle a las grabaciones uso disciplinario, sino formativo; primacía del valor del incumplimiento y la identificación de su corrección con un aspecto "formativo" sobre la eficacia del pacto colectivo.
No violation of the fundamental right to data privacy can be found if it due to work monitoring (on telephone attention), a repeated breach by the worker which allows valid disciplinary effects to be granted to the monitoring, despite the fact that there's a collective agreement that commits the company not to give the recordings disciplinary use, but rather formative; primacy of the value of worker misconduct and identification of its correction with a "formative" aspect on the effectiveness of the agreement.
Incidencia del reconocimiento por el trabajador de la infracción laboral cometida en el cómputo del plazo de prescripción de las faltas laborales.
Authors: Arias Domínguez Ángel
Published: March 2022

El reconocimiento por el trabajador de la infracción laboral cometida no obra el efecto de principiar el cómputo del plazo de prescripción de las faltas laborales si dicha asunción no es completa, o si la decisión extintiva empresarial se argumenta en hecho parcialmente diferentes.
The recognition by the worker of the labor offense committed does not have the effect of beginning the computation of the statute of limitations for labor absences if said assumption is not complete, or if the termination of the business decision is argued in fact partially different.
INVASIVE EXOTIC PLANT SPECIES AND THEIR INFLUENCE ON THE ENVIRONMENT, ECOSYSTEM SERVICES, ECONOMY AND HEALTH: A SEARCH
Authors: Premakumari Pradeep Damodaran , Sarayu Manoj Gopal , Das Greeshma Geetha Mohan , Babu Kalekkal Vasupillai Dinesh , Krishnan Remya , Lawarence Bosco , Siraj Sumayya Sabira , Pillai Arathy Rajendran , Syamala Sunu Kumar Soman , Murugan Kumaraswamy
Published: March 2022

Invasive exotic plant species (IEPS) is recognized as threat to the native biodiversity and leads to the loss of habitat for the indigenous species on the earth. Invasions not only tear down the native plant species but have adverse impacts on economy and human health. Many documented records from Western countries connected with alien species revealed altered ecosystem services and socio-economic conditions via diverse mode of actions. Even though, the ecological impacts of alien species were documented, there is a dearth of analysis regarding their economic quantification, livelihood considerations, biotechnological aspects and human health risk assessments are the need of the hour. The noxious exotic invasive plants in India were Ageratum conyzoides, Eupatorium adenophorum, Parthenium hysterophorus, Lantana camara, Mikania micrantha, Argemone mexicana and Eichhornia crassipes. In this context, an attempt was made to enlist the alien species of Kerala and a review to account the impacts of invasive exotic plant species on various aspects of the environment globally. Results regarding the alien species search revealed the following species such as Chromolaena odorata, Senna spectabilis, Hypoestes sanguinolenta, Maesopsis eminii, Eupatorium cannabinum, Mikania micrantha, Sphagneticola trilobata and Acacia mearnsii were intruded in to various ecosystems of Kerala after the repeated floods. They directly affect the germination and survival of local species, damage the quality of soil and affect ground water availability. Nearly 80 species were noted as alien species in Kerala by many state level surveys. Research in the direction of impact of alien species on socio-economic cultural aspects of life and derailment of ecosystem is not yet seriously carried from Kerala. Further, there is a paucity of the ecological models/indicators to establish interrelationship among global environmental changes, biodiversity and health, warranting future researches.
EVALUATION OF ANTIOXIDANT, ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF AQUEOUS METHANOLIC EXTRACT OF LINUM USITATISSIMUM
Authors: Daddala Guna Bhushana , Rani A. Swaroopa , Kumar A. Kiran
Published: March 2022

The present study was carried out to evaluate the antioxidant, antimicrobial study and phytochemical assessment of 80% v/v aqueous methanol extract of Linum usitatisimum. Flax seeds (Linum usitatisimum) are an ample source of lignans, which have antioxidant properties and promisingly reduce the effects of free radicals. The antioxidant activity of the extract was determined by free radical scavenging activity using DPPH radical and the activity was in the range of 26.7% to 98.6%. The average inhibitory concentration (IC50) was calculated. According to DPPH method, the IC50value of 80% v/v aqueous methanol extract of flax seeds was 5.56mg/ml. An in vitro antimicrobial assay by disc diffusion method was carried out. The results showed that 80% v/v aqueous methanol extract of seeds were effective against various test microorganisms. This paper also presents total phenolic assessment of 80% v/v aqueous methanol extract of flax seeds; the content was 20.91%. Furthermore, 80% v/v aqueous methanol extract was examined for qualitative phytochemical analysis and the results illustrate the presence of alkaloids, flavonoids, phenols, glycosides, steroids, terpenoids and proteins.
OXIDATION KINETICS OF ANILINE BY ZINC DICHROMATE
Authors: Subathra M. , Vellaisamy M.
Published: March 2022

The kinetics of oxidation of aniline by Zinc Dichromate (ZDC) has been studied in 50% acetic acid-water medium. The reaction shows unit order dependence each with respect to oxidant and substrate. The rate of reaction increases with increase in the [H+]. The rate of oxidation increases with decrease in dielectric constant of solvent suggests ion-dipole interaction. Increase in ionic strength by the addition of sodium perchlorate has no effect on the rate constant. There is no polymerization with acrylonitrile and absence of free radical is proved. The rate of the reaction has been conducted at four different temperatures. Thermodynamic parameters have been calculated. Based on the kinetics results, a suitable mechanism has been proposed.
STUDY OF COLLAGENASE PRODUCTION BY PENICILLUM SP. ISOLATED FROM DETERIORATED LEATHER SAMPLE
Authors: Kate Savita , Pethe Archana
Published: March 2022

Collagenase production by Penicillium sp. isolated from deteriorated leather sample was studied. The isolate produced collagenase 802.43±15.81U/ml at optimum temperature 30ºC and at pH 6.5 within 5 days using 1% collagen peptide type I as a substrate. Ca++ ions were found to be the best activator whereas EDTA and β-mercaptoethanol inhibited collagenase production. The isolate was also found to produce caseinase, gelatinase and keratinase. Experimental results propose that the isolate having ability to produce broad range of enzymes can be effectively used as a tool for leather industry waste treatment.
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF SOFOSBUVIR AND VELPATASVIR IN BULK AND TABLET DOSAGE FORM
Authors: Srawanthi Pinnoju , Dodda Sireesha , Battineni Jainendra Kumar
Published: March 2022

A simple, accurate, sensitive reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the simultaneous estimation of the Sofosbuvir and Velpatasvirin bulk and tablet dosage form. Separation of the analytes was carried out by using Kromasil C18 (250 x 4.6mm, 5μm) column with HPLC grade methanol as mobile phase at aflow rate of 1.0mL/min within the run time of 4 min. The detection wavelength selected was 261nm for Sofosbuvir (SOF) and 303nm for Velpatasvir (VEL).The retention times of SOF and VEL were 2.57 min and 2.86 min, respectively. The linearity of the method was found in the concentration range of 2.0-40.0μg/mL for SOF and 2.0- 25.0μg/mL for VEL with correlation coefficient (R2) >0.99. The method was validated according to ICH guidelines. This method was also successfully employed for the simultaneous estimation of SOF and VEL in marketed formulation.
BOBİ FRS’DE GERÇEĞE UYGUN DEĞER YAKLAŞIMI
Authors: İPEK Ayşegül
Published: March 2022

Günümüz ekonomik koşulları altında, finansal bilgi kullanıcılarının işletmelere ait finansal tablolarave bu tablolarda yer alan bilgilerin gerçeğe uygun bir şekilde sunulmasına olan ihtiyacının artması,Uluslararası Muhasebe ve Finansal Raporlama Standartları (UMS/UFRS)’nin kullanım alanının genişlemesininde etkisiyle gerçeğe uygun değer kavramının ön plana çıkmasına neden olmuştur.Ülkemizde 2005 yılından beri yürürlükte olan UMS/UFRS kapsamında gerçeğe uygun değer, genelolarak tarihsel maliyet anlayışını da içeren karma bir ölçüm sistemi olarak uygulanmaktadır. Ancakbu standartları uygulayan işletmeler Kamu Yararını İlgilendiren Kuruluşlar (KAYİK) ile sınırlandırılmıştır.Bu sınırlandırmaya ortadan kaldırmak ve Avrupa Birliği Muhasebe direktifine uymak amacıyla2017 yılında Büyük ve Orta Boy İşletmeler için Finansal Raporlama Standartları (BOBİ FRS) yayımlanmışve 2018 yılı itibariyle yürürlüğe girmiştir.Çalışma, TMS/TFRS kapsamında etkili olan gerçeğe uygun değer yaklaşımının BOBİ FRS kapsamındagerekliliğinin araştırılması ve hangi durumlarda, nasıl kullanılması gerektiğininin belirlenmesiamacıyla yapılmıştır. Bu amaçla tüm bölümler incelenmiş ve özellikli durumlarda yapılması gerekenmuhasebe kayıtları örneklendirilerek açıklanmıştır.
EFFECT OF NEBULIZED LIDOCAINE ON THE PERMEABILITY OF THE ALVEOLOCAPILLARY MEMBRANE UNDER EXPERIMENTAL MODEL OF VENTILATOR INDUCED LUNG INJURY IN RATS
Authors: Решетняк Н.А. , Колесников А.Н.
Published: March 2022

Цель работы: определить влияние небулизированного лидокаина на проницаемость альвеолокапиллярной мембраны в условиях экспериментальной модели вентилятор - индуцированного повреждения легких.

Aim: to determine the effect of nebulized lidocaine on the permeability of the alveolocapillary membrane in the experimental model of ventilator-induced lung injury.
Een nieuwe weg naar Rome?
Authors: Nelissen Nico , Verheul Wouter Jan
Published: March 2022

A new road to Rome? Alternative form of citizen participation in urban improvement

Municipalities are in a new phase of development. This requires rethinking how citizens can be involved in these developments. Instead of asking citizens to respond to municipal project initiatives, one of the (new) ways is to let citizens have their say about where, what and how urban improvements can be made. In this essay, the authors discuss what they mean by ‘areas for improvement’ and discuss two experiments – in two of the oldest Dutch cities: Maastricht and Nijmegen – of citizen participation that are intended to address such areas. In their view, in this way ‘a new, but obviously not the only, way to Rome is created’ in terms of citizen participation.
Geografia: ciência e profissão
Authors: Oliveira Emanuel dos Santos de
Published: March 2022

Este estudo objetivou analisar a relação entre a Ciência Geográfica e o exercício profissional da Geografia dando enfoque à correspondência deste com o processo formativo. Através de pesquisas bibliográfica e documental fez-se o levantamento e a leitura dos textos que abordam, orientam e/ou regulamentam a Ciência Geográfica, o processo formativo e o exercício profissional da Geografia no Brasil. Após enunciar as três profissões da Geografia, as especificidades e as correlações entre elas foram explicadas. Concluiu-se que o profissional da Geografia é definido conforme a modalidade de sua formação científica e as atividades que desempenhará. Dentre os resultados apresentados estão: um quadro comparativo das categorias profissionais da Geografia no Brasil e uma seção apresentando propostas para a superação dos seus desafios formativos e laborais.
Geodiversidade, turismo e educação: a divulgação científica virtual no período de pandemia
Authors: Araujo Raphaela A. de Oliveira , Vieira Gabriel Flora , Souza Paulo Henrique de , Santos Clibson Alves dos
Published: March 2022

Os estudos concernentes a Geodiversidade tem sua gênese na década de 1990, tendo a convenção de Malvern como marco conceitual, desde então, os mesmos vêm se consolidado em pesquisas em todo o globo, possibilitando novas interpretações da natureza e dos sistemas ambientais inerentes a vida humana. Este artigo tem por finalidade apresentar uma breve análise sobre os conceitos da Geodiversidade, Geoconservação e Geoturismo, os entendendo como uma tríade para o conhecimento e preservação do meio abiótico. Desta forma, também se busca neste trabalho evidenciar a importância da divulgação geocientífica neste período de pandemia, o qual trouxe a imposição de um novo paradigma para a comunicação e distribuição de informações, se apropriando deste para proporcionar o conhecimento acerca da diversidade abiótica. Ainda neste artigo será também analisado o aparecimento destes termos na educação básica por meio da Base Nacional Comum Curricular, documento que norteia as competências e habilidades a serem desenvolvidas na etapa de ensino. Em consequência à importância empregada à divulgação geocientífica voltada ao Geoturismo, este artigo conta com diversos exemplos de iniciativas pioneiras que buscam explicitar possibilidades de interligação do lazer e o conhecimento científico.
Patrimonialização, território usado e processo de registro da feira livre de domingo de Alfenas (MG) como bem cultural imaterial do município
Authors: Porto Gil Carlos Silveira
Published: March 2022

O presente texto é um ensaio geográfico que busca explicar o processo de patrimonialização da feira livre de domingo de Alfenas (MG) considerando o conceito de território usado. Para tanto, discorreu-se inicialmente sobre o conceito de feira livre, para em seguida apresentar uma breve recomposição de sua origem enquanto atividade de diferentes grupos. Após a composição desse quadro conceitual e genético, foram apresentados processos de registro de feiras no Brasil, como parte do processo de patrimonialização global, ao qual se insere o registro da feira de Alfenas como bem cultural intangível, ocorrido em 2019. Em seguida, buscou-se abordar a feira livre como território usado, bem como lugar constituído por feirantes, consumidores e frequentadores e apontar significados construídos com o processo de registro. Para a construção deste texto foram consultados livros, artigos, dossiês e outros documentos que possibilitaram caracterizar o fenômeno e operacionalizá-lo a partir de conceitos geográficas. Pretendeu-se com a discussão produzida valorizar a dimensão espacial das feiras livres, discutir a possibilidade de que outras feiras brasileiras se tornem patrimônios imateriais culturais e contribuir para ampliação de políticas do governo voltadas para a preservação do patrimônio cultural.
As conquistas da Educação do Campo e o avanço da extrema-direita: desafios e perspectivas
Authors: Almeida Martins Maria de Fátima , Bruna da Cruz Abigail , Lencioni Mattos Santos Leonardo , Nunes Jefferson
Published: March 2022

A pressão dos movimentos socioterritoriais de luta pela terra, em articulação com diferentes instituições da sociedade civil organizada e, associada a isso, um governo de esquerda, que assumiu a educação para as escolas do campo como política pública, contribuíram para o fortalecimento da Educação do Campo. Neste compromisso coletivo, o objetivo foi garantir a criação e manutenção das escolas em espaços rurais com uma proposta pedagógica vinculada à sua realidade, investir na formação de professores voltados para atender essas escolas rurais e a elaboração de materiais didáticos destinados a essa população. Essas ações foram garantidas por políticas públicas constituídas por dentro do Programa Nacional de Educação do Campo (PRONACAMPO), sendo uma dessas políticas o Programa Nacional do Livro Didático do Campo (PNLD Campo). Mas, com o fortalecimento da extrema-direita e da bancada ruralista na política brasileira desde 2016, está em curso um ataque às políticas voltadas ao campo, resultando em fechamento e até mesmo a destruição de algumas escolas rurais, corte de verbas na política de formação de professores para o campo, o encerramento do PNLD Campo e a desarticulação do Programa Nacional de Educação na Reforma Agrária (PRONERA). Esse contexto favorece o fortalecimento do movimento organizado por setores do agronegócio, com objetivo de controlar a educação no espaço agrário brasileiro. Neste sentido, discute-se nesse trabalho um breve histórico da Educação do Campo e das políticas públicas educacionais voltadas ao meio rural. Aponta-se algumas das disputas atuais que abarcam a educação do/no campo, bem como a relação dessas disputas com o aumento do poder das elites agrárias a partir de 2016, demonstrando como a concentração fundiária está na base desses processos.
Measuring the Root Length of Peanuts Grown in Rhizotrons Using Computer Vision
Authors: Stefanello Leonardo Michalski , Silva Leonardo Paillo da , Dayrell Luís Henrique Soares , Ferrari Neto Jayme , Pistori Hemerson , Nucci Higor Henrique Picoli
Published: March 2022

Peanut is one of the most grown leguminous crops in the world, but it can suffer during water deficit periods. In this paper, a new method to help monitoring root growth for laboratory experiments with this plant is proposed. By using a new combination of smoothing, thresholding, morphological filtering and skeletonization, our method has achieved a correlation of 0.968 with the Tennant's standard approach.
Application of Convolutional Neural Network in Coffee Capsule Count Aiming Collection System for Recycling
Authors: Silva Henrique Wippel Parucker da , Santos Gilmário Barbosa dos
Published: March 2022

The coffee capsules brought practicality and speed in the preparation of the drink. However, with its popularization came a major environmental problem, the generation of a large amount of garbage, which for 2021 has an estimated 14 thousand tons of garbage, only coming from the capsules. To avoid this disposal it is necessary to recycle them, however it is not a trivial job, since they are composed of various materials, as well as the collection of these capsules presents challenges. Therefore, a collection system is of great value, which, in addition to being automated, generates bonuses proportional to the quantity of discarded capsules. This work is dedicated preliminary tests on the development of such a system using a convolutional neural network for the detection of coffee capsules. This algorithm was trained with two image sets, one containing images with reflection and the other without, which presented an accuracy of approximately 97%.
This Article Corrects: “Gender-based Barriers in the Advancement of Women Leaders in Emergency Medicine: A Multi-institutional Qualitative Study”
Authors: Graham Emily , Ferrel Meganne , Wells Katie , Egan Daniel , MacVane Casey , Gisondi Michael , Burns Boyd , Madsen Troy , Fix Megan
Published: March 2022

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Foglar v nás: Záhada hlav a lomu
Authors: Jirásek Ivo , Němec Jiří , Macků Richard
Published: March 2022

The presentation of the personality, work and influence of Jaroslav Foglar is not limited to a historical biographical sketch, but seeks, among other things, on the basis of an empirical survey (n = 1174), to provide a comprehensive professional treatment of a relatively complex social phenomenon. The evidence of the influence of the reading experience usually acquired in childhood on the whole future life, as well as the interest of several scientific disciplines (comic studies, literary science, religious studies, pedagogy) in the specific methods of the scout educator, writer of boys’ literature and editor of several children’s magazines is thus the first book venture going beyond theoretical considerations and hypotheses towards evidence based on surveys of readers and fans of Foglar’s texts.
Perceived Racial/Ethnic Discrimination and Depressive Symptoms among Adolescents Living in the Cherokee Nation
Authors: Barry Caroline M. , Garrett Brady A. , Livingston Melvin D. , Kominsky Terrence K. , Livingston Bethany J. , Komro Kelli A.
Published: March 2022

The objective of this study was to examine the longitudinal relationship between perceived racial/ethnic discrimination and depressive symptoms among adolescents living in the Cherokee Nation, as well as the potential moderating roles of race and social support. Self-reported survey data were analyzed from a sample of high school students (n = 1,622) who identified as American Indian only, American Indian and White, and White only. Compared to students who reported no discrimination on the basis of race, those who reported ever having experienced discrimination scored, on average, 1.62 units higher on the depressive symptoms scale six months later (p = .0001, 95% CI: 0.90, 2.33), while adjusting for age, race, gender, baseline depressive symptoms, enrollment in a free/reduced-price lunch program, and social support. Discrimination intensity did not significantly predict depressive symptoms among those reporting some frequency of discrimination. Race and social support did not modify either effect. These findings may inform development of interventions to promote mental health among American Indian adolescents.
Peirce en España: panorama bibliográfico
Authors: Castañares Wenceslao
Published: March 2022

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Materiales para una semiótica de la cultura española (siglos XVI a XIX)
Authors: Abad Francisco
Published: March 2022

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Luis Beltrán Almería: Palabras transparentes. La configuración del discurso del personaje en la novela. Madrid: Cátedra. 1992
Authors: Vilavedra Dolores
Published: March 2022

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Bajtín y la teoría de la historia literaria: el caso de la picaresca
Authors: Cabo Aseguinolaza Fernando
Published: March 2022

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J. Romera Castillo, A. Yllera, M. García-Page y R. Calvet, Escritura autobiográfica. Actas del II Seminario Internacional del Instituto de Semiótica Literaria y Teatral. (Madrid: Visor Libros, 1993)
Authors: Torres Lara Agustina
Published: March 2022

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Re-Evaluating Sharpe Ratio in Hedge Fund Performance in Light of Liquidity Risk
Authors:   Poznan University of Economics and Business, Van Horne Richard , Perez Katarzyna
Published: March 2022

This paper demonstrates how the Sharpe Ratio can be modified by altering the measure of “total risk” in the denominator of the Sharpe Ratio (i.e., the standard deviation) to include liquidity risk, a major risk for investors in hedge funds that is missing from the standard Sharpe Ratio formulation. We refer to our liquidity-risk-adjusted performance ratio as the LRAPR. The results of our analysis of 1186 hedge funds alive in 2012-2020 show that funds with higher liquidity risk exhibit higher Sharpe Ratios and higher Alphas (as estimated in a 7-factor model that does not incorporate liquidity risk). We posit that analysts and investors should not necessarily take these higher Sharpe Ratios and higher Alphas as indications of fund superiority; what appears to be superior manager skill may rather be a compensation for bearing liquidity risk. Our LRAPR is a tool that analysts or investors could use to compare funds on a more equal footing, adjusting for differential liquidity risk across funds.
How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition
Authors: Goodman Kerry Marie , Katsamba Phinikoula S , Rubinstein Rotem , Ahlsén Göran , Bahna Fabiana , Mannepalli Seetha , Dan Hanbin , Sampogna Rosemary V , Shapiro Lawrence , Honig Barry
Published: March 2022

The stochastic expression of fewer than 60 clustered protocadherin (cPcdh) isoforms provides diverse identities to individual vertebrate neurons and a molecular basis for self-/nonself-discrimination. cPcdhs form chains mediated by alternating cis and trans interactions between apposed membranes, which has been suggested to signal self-recognition. Such a mechanism requires that cPcdh cis dimers form promiscuously to generate diverse recognition units, and that trans interactions have precise specificity so that isoform mismatches terminate chain growth. However, the extent to which cPcdh interactions fulfill these requirements has not been definitively demonstrated. Here, we report biophysical experiments showing that cPcdh cis interactions are promiscuous, but with preferences favoring formation of heterologous cis dimers. Trans homophilic interactions are remarkably precise, with no evidence for heterophilic interactions between different isoforms. A new C-type cPcdh crystal structure and mutagenesis data help to explain these observations. Overall, the interaction characteristics we report for cPcdhs help explain their function in neuronal self-/nonself-discrimination.
Growth, maturity, and diet of the pearl whipray (Fontitrygon margaritella) from the Bijagós Archipelago, Guinea-Bissau
Authors: Clements Owen N. , Leurs Guido , Witbaard Rob , Pen Ido , Verkuil Yvonne I. , Govers Laura L.
Published: March 2022

The pearl whipray Fontitrygon margaritella (Compagno & Roberts, 1984) is a common elasmobranch in coastal western African waters. However, knowledge on their life-history and trophic ecology remains limited. Therefore, we aimed to determine the growth, maturity and diet of F. margaritella from the Bijagós Archipelago in Guinea-Bissau. Growth was modelled with: von Bertalanffy, Gompertz and logistic functions. Model selection revealed no model significantly outperformed another. The sampled age ranged from less than 1 to 7 years (1.8 ± 1.9 cm, mean ± standard deviation) and size (disc width) ranged from 12.2 to 30.6 cm (18.7 ± 5.2 cm). Size-at-maturity was estimated at 20.3 cm (95% CI [18.8–21.8 cm]) for males and 24.3 cm for females (95% CI [21.9–26.5 cm]), corresponding ages of 2.2 and 3.9 years. The diet differed significantly among young-of-the-year (YOY), juveniles and adults (p = 0.001). Diet of all life stages consisted mainly of crustaceans (27.4%, 28.5%, 33.3%) and polychaetes (12.5%, 26.7%, 20.3%), for YOY, juveniles and adults respectively. This study shows that F. margaritella is relatively fast-growing, matures early and experiences ontogenetic diet shifts. These results contribute to status assessments and conservation efforts of F. margaritella and closely related species.
Rotas de bebidas e turismo cervejeiro
Authors: Munhoz Janete Probst , Paixão Dario Luiz Dias , Caldas Lia Maura , Molteni Angélica da Cunha
Published: March 2022

A evolução mundial das cervejarias artesanais é notória, assim como a das rotas de bebidas e do segmento turismo cervejeiro, pois de acordo com Coelho-Costa (2015), a cerveja se caracteriza como um elemento indispensável para que um destino possa desenvolver atividades no turismo cervejeiro. No estado do Paraná, um dos maiores produtores do Brasil, levanta-se a problemática sobre a exis-tência de atratividade de seus empreendimentos para conformar circuitos turísticos. O presente es-tudo buscou evidenciar o potencial do turismo cervejeiro no Paraná, a partir da caracterização de suas microcervejarias artesanais, assim como a sua atratividade para a visitação e a conformação de rotas de bebidas. Como metodologia, desenvolveu-se uma pesquisa exploratória por meio de levantamento bibliográfico e documental sobre os temas. Também, realizou-se a identificação das rotas de bebidas do Brasil, a partir da análise do Mapa do Turismo Brasileiro, de páginas eletrônicas oficiais de divulgação e do site de comercialização Tripadvisor. Para a pesquisa de campo, utilizou-se um questionário estruturado para identificar, mapear e caracterizar os 65 pequenos produtores cervejeiros do estado paranaense em uma parceria com o Sebrae/PR e a Procerva –Associação das Microcervejarias do Paraná. Como resultado, identificou-se que os empreendimentos analisados possuem atratividade por sua inovação, produção, diversidade e qualidade, constituindo potencial favorável ao desenvolvimento de novos produtos, tais como rotas de bebidas e outrasatividades de visitação, aproveitando o amplo crescimento do turismo cervejeiro no Brasil, apontado pelo Ministé-rio de Agricultura, Pecuária e Abastecimento (MAPA, 2020), que exibe um crescimento no número de estabelecimentos cervejeiros.
Prevalence of Female Pelvic Pathologies: Cross-sectional Study among Patients Undergoing Magnetic Resonance Imaging for Pelvic Assessment
Authors: Kulkarni Devendra Vikas , Bhadane Sushant Hari , Bani Ajay Mrutyunjaya , Jagdale Amol Murlidhar
Published: March 2022

Introduction: A wide variety of pathologies affect the female genital tract. Magnetic Resonance Imaging (MRI) has recently become a useful tool for the evaluation of female pelvic pathologies owing to certain benefits over ultrasonography. This modality, in the long run would be helpful in improving early diagnosis and clinical management of many patients. Aim: To demonstrate the wide spectrum of female pelvic pathologies that can be diagnosed using MRI. Materials and Methods: It was a cross-sectional study carried out at Department of Radiodiagnosis among 75 patients referred to the MRI department for assessment of female pelvic organ pathologies. Appropriate MRI sequences and multiplanar imaging were performed for every patient and findings noted in a pre-designed proforma. Results: On MRI, 46 (61.3%) patients had Uterine and Cervical pathology and 32 (42.7%) patients had Adnexal pathology among others. Vaginal pathologies were noted in 10 (13.3%) patients. Rectal and urinary bladder pathologies were seen in 5 (6.7%) and 1 (1.3%) patients respectively. Conclusion: The study shows that MRI was especially useful in detecting a wide spectrum of female pelvic pathologies including benign lesions such as fibroids, congenital mullerian anomalies, adenomyosis and endometriosis; and malignancies.
Diagnostic Performance of ElastPQ Point Shear Wave Elastography for Hepatic Fibrosis in Hepatitis B and Hepatitis C Patients
Authors: Pradeep Hagalahalli Nagarajegowda , Mahesh Seetharam , Rashmi Nagaraju K , Pradeepkumar Nagarajaiah Chandandur , Nanjaraj Chakenahalli Puttaraju , Prathibha Shivadas P , Ravindra Hanji , Supraja Moorthy
Published: March 2022

Introduction: Chronic viral hepatitis is a condition of hepatotropic viral infection associated with chronic inflammation, hepatocyte injury and progressive fibrosis. Non-invasive assessment of liver fibrosis in chronic hepatitis B and C patients has been increasing and used instead of liver biopsy. Aim: To assess the diagnostic performance of ElastPQ Point Shear Wave Elastography (ElastPQ PSWE) with liver biopsy as the gold standard and comparing these results with other serum fibrosis markers namely Aspartate to Platelet Ratio Index (APRI), Fibrosis-4 Score (FIB4). Materials and Methods: A cross-sectional study was carried out in which 73 patients underwent ElastPQ PSWE and Histopathological Examination (HPE) with METAVIR Scoring system staging. Serum fibrosis indices including APRI and FIB4 values were calculated. The diagnostic performance of ElastPQ PSWE, APRI and FIB4 was evaluated using Area Under Receiver Operating Characteristic (AUROCAUROC) curve analysis, correlations of ElastPQ PSWE, APRI and FIB4 ratio index with histopathological findings (as the reference standard) were determined using Spearman’s correlation coefficient. Results: Study included 73 patients with chronic hepatitis B and hepatitis C, of which 8 (10.96%) were no/early fibrosis (F0- F1); 20 (27.40%) were significant fibrosis (F2); 22 (30.13%) were severe fibrosis (F3), and 23 (31.51%) were cirrhosis (F4). There was a significant positive correlation between different stages of liver fibrosis by liver biopsy and liver stiffness detected by ElastPQ PSWE (r=0.912, p <0.0001). ElastPQ PSWE exhibited higher diagnostic accuracy than the APRI and FIB4 for the diagnosis of F0-F1 AUROC 0.980, 0.730, 0.710, respectively; F2 AUROC 0.840, 0.662, 0.669 respectively; F3 0.564, 0.528, 0.500 AUROC, respectively; and F4 0.967, 0.783, 0.751 AUROC, respectively. Using AUROC curve, the optimal cut-off of ElastPQ PSWE for stages F0-F1 is ≤3.9 kilopascals (kPa); F2 is ≤7.2kPa; F3 is ≥7.2kPa and F4 is≥10kPa. Conclusion: ElastPQ PSWE is a promising non-invasive method used for the evaluation of liver fibrosis, with high diagnostic performance, high Negative Predictive Value (NPV) and good specificity in evaluation of hepatitis B and hepatitis C patients.
Perception and Practices of COVID-19 in Rural Areas of Southeastern Nigeria: A Community-based Cross-sectional Survey
Authors: I. Nnamonu Emmanuel , C. Ani Ogonna , Okafor Love C. , C. Nwosu Godwin , A. Okeke Obiageli , Ikwuegbu Pauline N. , P. Ota Chukwudi , F. Egwim Chukwuemeka , L. Agu Chukwuemeka , U. Ononye Benjamin
Published: March 2022

Aims: Despite all efforts made globally by governments of various nations and all concerned agencies through preventative measures, quick testing, isolation, shutting down of societies and economy, the virus still succeeded in spreading through communities perhaps due to the wrong perspective, in addition to surveillance, prevention and management challenges. This study evaluated the perception and practices of covid-19 in rural areas of southeastern Nigeria.

Study Design: The study adopted a community-based cross-sectional survey design that investigated awareness, perspective, surveillance challenges, prevention, management and economic impact in rural settlement areas of south-east, Nigeria.

Place and duration of study: This study was be conducted in rural settlement areas of south-east Nigeria (Abia, Anambra, Ebonyi, Enugu, and Imo states). February – April, 2021.

Methodology: Data was collected by the use of the questionnaire. Five hundred copies were administered per state.

Results: Most participants (2464, 98.6%) heard first of COVID-19 through radio/television (1409, 56.3%), social media (539, 21.5%) and their friends/relatives (418, 16.7%); 1896 (75.8%) believed in the existence of COVID-19 infection. However, the majority in Ebonyi state (309, 61.8%) had their disbelief on the existence of COVID-19. Participants confirmed having knowledge of COVID-19 testing (2319, 92.8%) and isolation centers (2299, 92.0%), however, a major challenge was lack of (1698, 67.9%) or no awareness (550, 22.0%) of masses testing centre in their areas. A few individuals (392, 15.7%) reported having experienced one or two COVID-19 symptoms about 3 months ago. Knowledge on how to prevent contracting COVID-19 is relatively high (66.7%) among the respondents. COVID-19 induced economic burden amongst residents were mainly as a result of the imposition of lockdown to movements and businesses (1098, 43.9%), disruption of studies (959, 38.4%), increased hunger (950, 38.0%), high expenditure (894, 35.8%) and loss of job/income (816, 32.6%).

Conclusion: It is concluded that the majority of the people in southeast Nigeria are aware of the possible existence of Covid-19 in their area.
Alternative Substrate with Cupuaçu Bark Promotes Morphophysiological Quality in Yellow Passion Fruit Seedlings
Authors: Da Silva Sandra Bezerra , Nascimento Luan De Oliveira , Oliveira Roger Ventura , Andrade Neto Romeu De Carvalho , Oliveira Martins Marcio De , Silva De Souza Clemeson , Souza e Souza Luís Gustavo De
Published: March 2022

The use of agricultural residues for the production of alternative substrate is essential to reduce seedling production costs, as well as to reduce the environmental impacts resulting from the use of commercial substrates. Thus, the objective of this study was to evaluate the morphological and physiological performance of Passiflora edulis fruit seedlings as a function of alternative Theobroma grandiflorum bark substrates. The experiment was carried out in a screened nursery with sombrite of 50%, with a randomized block design with three replications and five plants per plot. The treatments consisted of the combination of ground and crushed cupuaçu bark in percentages of 20%, 40%, 60% and 80%. Liquid photosynthesis, stomatal conductance, internal CO2 concentration, transpiration, plant height, stem diameter, main root length, number of leaves, dry and fresh shoot and root weight and Dickson Quality Index were evaluated. The morphological and physiological performance of passion fruit plants was influenced by the cupuaçu bark concentration. Substrates containing 20 to 40% cupuaçu bark resulted in better seedlings, as they promoted increased net photosynthesis, gas exchange, leaf number, higher root growth and development, and larger stem diameter and shoot height. Consequently, the Dickson quality index showed excellent values, which shows an improvement in the biometric and physiological characteristics of the passion fruit seedlings produced with substrates based on cupuaçu bark.
Oral mucosal Cryoglobulin [ICD-10-CM Diagnostic Code D89.9 Cryoglobulin], Oral Mucosal Herd Immunity and the Immune Herd Plots among Periodontal Disease Patients
Authors: Shnawa Ibrahim M. S. , AL-Amedie Baha H. H. , AL-Fatlawi Zainab H.
Published: March 2022

Forty five patients were diagnosed by specialist dentist of the team as periodontal disease patients. Basically they were found to be chronic periodontitis and chronic gingivitis. The study male and female patient groups [25 males and 20 females] were subjected to the detection of oral mucosal cryoglobulin and tempts to use cryoglobulin as a marker for oral mucosal herd immunity among these patients. Oral mucosal cyoprotein solutions were separated and characterized as oral mucosal cryoglobulin [ICD-10-CM Diagnostic code, D89.9 Cryglobulin]. Mucosal cryocrit percentages were ranged from one to seven percent. Oral mucosal cryoglobulin concentrations were ranged between 0.13 up to 2 mg/dl. In chronic periodontitis patients and 0.15 up to1.96 mg/dl.in chronic gingivitis patients. The individuals Mucosal herd immunity constitutes three basic immune fractions; low, moderate and high cryoglobulin responders. The immune herd plot types were matched as Gaussian distribution plot types. The findings of oral mucosal cryoglobulin among these patients in clinically indicative concentrations for the potential role may be played in the pathogenesis of chronic gingivitis and chronic periodontitis as it may cause precipitates in the local blood vessels of gum and periodotium.
Comparative Analysis of Nutritional and Antioxidant Characteristics of Different Pakistani and Exotic Almonds
Authors: Rizwan Muhammad , Butt Masood Sadiq , Rakha Allah , Hussain Fatma
Published: March 2022

Health boosting potential of almonds is attributed to its antioxidant potential and rich nutritional profile containing a blend of multifarious nutrients and phytochemicals. These traits considerably vary amongst different genotypes and varieties. Hence, current research was planned to explore the basic nutritional composition and antioxidant potential of four different almond genotypes i.e. Patasa & Talwar (Pakistani) and Abdul Wahidi & Katha (Afghani). Amongst, Talwar and Abdul Wahidi showed better nutritional profile followed by Patasa and Katha. Proximate analysis revealed higher quantities of oil in Talwar and Abdul Wahidi i.e. 51.12±0.97 and 50.64±0.86%, respectively. Katha contained higher ash contents. Likewise, Abdul Wahidi and Talwar were also high in fiber content as 13.11±0.39 and 12.45±0.37, correspondingly. Substantial amount of protein was quantified in Abdul Wahidi. Talwar almonds were proved as a good source of potassium and magnesium, 14.02±1.12 mg/g and 3.10±0.24 mg/g, respectively. Likewise, Abdul Wahidi contained higher amount of phosphorous, 9.17±1.10 mg/g. However, Patasa were high in calcium. High performance liquid chromatography (HPLC) based quantification showed that vitamin-E (α-tocopherol) was highest in Patasa trailed by Abdul Wahidi and Talwar. However, Katha almonds were low in vitamin-E. In vitro analysis exhibited Talwar and Abdul Wahidi with the highest flavonoids contents. Whereas, Patasa and Abdul Wahidi almonds had promising amounts of total phenolics. Antioxidant assays (DPPH and ABTS) explicated better radical scavenging activity by Talwar and Abdul Wahidi almonds whilst Katha almonds showed better performance for FRAP assay.
Sodium Silicate Catalyst for Synthesis Monoacylglycerol and Diacylglycerol-Rich Structured Lipids: Product Characteristic and Glycerolysis–Interesterification Kinetics
Authors: Wangi Inasanti Pandan , Supriyanto Supriyanto , Sulistyo Hary , Hidayat Chusnul
Published: March 2022

Sodium silicate as heterogeneous base catalysts is more environmentally friendly and easily separated by filtration. The objective of this research was to evaluate the activated sodium silicate as catalyst for synthesis of monoacylglycerol (MAG) and diacylglycerol (DAG)-rich structured lipids (SLs) from a palm olein-stearin blend. Sodium silicate was activated and functional group was characterized. Reaction was performed using 5% catalyst (w/w) at various reaction temperature (70–120 °C) for 3 h in a batch stirred tank reactor. Physical properties of SLs, such as melting point, slip melting point, and hardness of SLs were determined. Reaction kinetics were also evaluated. The results show that Si−O bending was reduced and shifted to a Si−O−Na and Si−O−Si functional groups after sodium silicate activation. Temperature had a significant effect on SLs composition at higher than 90 °C. An increase in temperature produced more MAG, resulting in better product physical properties. The best reaction condition was at 110 °C. Rate constants and the Arrhenius equation were also obtained for each reaction step. In summary, the activated sodium silicate catalyzed glycerolysis-interesterification reaction, which produced MAG and DAG at temperature higher than 90 °C. Therefore, the physical properties of SLs were improved. Copyright © 2022 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Interdomain electron transfer in flavohaemoglobin from Candida norvegensis with antibiotic azole compounds
Authors: Kobayashi Kazuo , Igarashi Jotaro , Kozawa Takahiro
Published: March 2022

Flavohaemoglobins (FlavoHbs) function as nitric oxide dioxygenases, oxidizing nitric oxide with nitrite and shuttling electrons from NAD(P)H via FAD and O2. Here, using pulse radiolysis, we investigate intramolecular electron transfer between FAD and haem b in FlavoHbs. We found that reduction of FlavoHb with hydrated electrons proceeded via two phases: an initial fast phase and a second slower process. Absorbance measured at 600 nm revealed fast flavin reduction followed by a slower decrease corresponding to reoxidation of FAD. The slower process was partially lost in FlavoHbs lacking FAD. These results suggest that the slower phase is attributable to intramolecular electron transfer from FAD to the haem iron. The rate constant in the absence of azole compound (3.3 × 103 s‐1) was accelerated ~ 10‐fold (2.7 × 104 s‐1) by the binding of econazole, reflecting a conformational change in the open‐to‐closed transition.