bluuebunny/crossref_metadata_2025 huggingface dataset:
Dexamethasone intravitreal implant (Ozurdex) in diabetic macular edema: real-world data versus clinical trials outcomes
Authors:   Department of Ophthalmology, Centro Hospitalar de Setúbal, Setúbal 2910-549, Portugal, Neves Pedro , Matias Inês ,   Department of Ophthalmology, Centro Hospitalar de Setúbal, Setúbal 2910-549, Portugal, Rodrigues João ,   Department of Ophthalmology, Hospital Beatriz Ângelo, Loures 2674-514, Portugal, Santos Margarida ,   Department of Ophthalmology, Hospital da Luz Setúbal, Setúbal 2900-722, Portugal, Dutra-Medeiros Marco ,   Department of Ophthalmology, Centro Hospitalar Lisboa Central, Faculdade de Ciências Médicas, NOVA University of Lisbon, Lisbon 1990-237, Portugal, Martins David ,   Department of Ophthalmology, Hospital da Luz Setúbal, Setúbal 2900-722, Portugal
Published: September 2021

AIM: To investigate the safety and efficacy of intravitreal dexamethasone implants (Ozurdex®/DEX) in patients with diabetic macular edema (DME) either naïve or non-naïve to anti-VEGF therapies who switched to DEX implant independent of response to anti-vascular endothelial growth factors (anti-VEGFs).
METHODS: This was an audit retrospective review of medical records of patients with DME who switched to the DEX intravitreal implant. Patients were divided into 2 groups: patients naïve to antiangiogenic therapy and patients who were previously treated with anti-VEGFs. Data regarding demographics, changes in mean best-corrected visual acuity (BCVA), central macular thickness (CMT), and intraocular pressure (IOP) was collected over 6mo. The demographic data mean changes in BCVA, CMT, and IOP were compared. Six-month follow-up data of 47 patients (57 eyes), who either switched to DEX implant irrespective of response to previous treatments or were treatment naïve before receiving DEX implant, was collected.
RESULTS: Improvement in mean BCVA was observed from 1-4mo after injection with a decreased effect at month 6 as expected, with better outcomes in naïve compared to non-naïve patients. A statistically relevant decrease in mean CMT was observed during the follow-up period. An increase in mean IOP was observed in the first 2mo after DEX therapy. The mean number of injections of the overall population during the 6mo was 1.3. A subgroup analysis showed no relevant difference between phakic versus pseudophakic patients relative to measured outcomes. There was no cataract progression during the follow-up period and no adverse events reported.
CONCLUSION: This real-life setting study shows that intravitreal DEX implant is effective and safe. The timings of greater therapeutic impact are concordant with previous studies and suggest that earlier treatment with corticosteroids may have an additional benefit in naïve patients.
Visual differences in topography-guided versus wavefront-optimized LASIK in the treatment of myopia: a Meta-analysis
Authors:   Department of Ophthalmology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing 400010, China, Hu Peng-Cheng , Wu Xian-Hui ,   Department of Ophthalmology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing 400010, China, Li Yan-Qing ,   Department of Ophthalmology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing 400010, China, Li Ke-Wei ,   Department of Ophthalmology, the First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing 400016, China
Published: September 2021

AIM: To investigate the potential differences between topography-guided (TG) and wavefront-optimized (WFO) laser in situ keratomileusis (LASIK) for the treatment of myopia.
METHODS: A systematic literature search was performed to determine relevant trials comparing LASIK with TG and WFO from the time of library construction to August 2020, and The PubMed, Cochrane, Web of Science, EMBASE and Chinese databases (i.e. CNKI, CBM, WAN FANG and VIP) were accessed. The data on visual acuity, refractive status and wavefront aberration were retrieved and evaluated from three to six months after surgery. STATA (version 14.0) software was used for statistical analysis. A cumulative Meta-analysis was simultaneously performed.
RESULTS: Eleven studies with a total of 1425 eyes were incorporated. No statistically significant differences were evident between TG and WFO ablation in the proportion of eyes achieving an uncorrected distance visual acuity (UCVA) of 20/20 or better (P=0.377), gaining one line or more (P=0.05), postoperative cylinder (P=0.40), vertical coma (P=0.593) and horizontal coma (P=0.957). After TG ablation, the proportion of the patients’ eyes of which postoperative refraction is within ±0.5 diopter of the target refraction was significantly higher than that undergoes WFO (P=0.003). As opposed to the WFO group, manifest refraction spherical equivalent (MRSE; P=0.000) was lower, and UCVA (P=0.005) was better in the TG group. The higher-order aberrations (HOAs; P=0.000), spherical aberration (P=0.000) and coma (P=0.000) were significantly lower in TG group. The cumulative Meta-analysis illustrated that the proportion of eyes achieving UCVA of 20/20 or better, postoperative refraction within ±0.5 diopter, and MRSE has steady between the two groups.
CONCLUSION: Both TG-LASIK and WFO-LASIK are safe, effective, and predictable for correcting myopia. TG-LASIK may produce fewer aberration and is more precise than WFO-LASIK.
Between functionalism and semiotics: two ways to change the functions and meanings of technical objects
Authors: Yastreb Natalya A.
Published: September 2021

The article is devoted to the analysis of practices and ways of inventing new functions of technical objects. The purpose of the work is to identify, classify and describe practices that cause new functions of technical objects. The function of a technical object (artifact) is understood as the work performed by an artifact and aimed at realizing a certain purpose set by a person. The authors analyze the duality of the nature of the artifact, due to its physical structure and its involvement in purposeful human activity. The functional and semiotic approaches to understanding technology are compared. The differences between function and meaning of artifacts are identified. The case method is used to analyze how new artifact functions appear. Reinterpretation is defined as a way to create new meanings for an artifact without changing its physical structure of the artifact. Adaptation is considered as the adaptation of technical objects to the needs of the user.It is shown that new functions appear in artifacts both on the physical level, through the introduction of constructive changes, and on the semiotic level, through the transformation of the semantic content of objects. In the final part of the article, a conclusion about the possibility of applying the results obtained in the field of marketing and promotion of technical systems and devices is made.
Elements of expressionism in the story of A. Green «Gray Car»
Authors: Pozdnyakov Konstantin S.
Published: September 2021

The topic of the work is relevant, since at present the Russian literary criticism is rediscovering the features of the artistic expression of Soviet literature of the 1920s. The aim of the study was to discover the features of the poetics of Greens text that allow us to identify the novel under consideration as expressionist. Research methods used in the article: comparative-historical and semantic analysis of texts. At the beginning of the article, the research of the novella Gray Car by A.V. Polupanova and L.U. Zvonareva is considered, inaccuracies and obvious factual errors are noted, indicating a lack of understanding of the text, a mixture of such forms of expression of the authors position (according to B.O. Korman) as hero-narrator and author-narrator. As an empirical material, in addition to the novel by A. Green, the works of G. Mayrink, F. Kafka and L. Perutz were used. As a result of consideration of the novels the Golem, Castle, the Cossack and the Nightingale, the Wizard of judgment was allocated with the following features art in the world of the expressionist literary works: a) the problem of identity associated, as a rule, the main character; 2) semema madness, which became a constant for expressionist texts; 3) mysterious (hidden) order of a seemingly chaotic world; 4) the lack of success of speech acts. All these features were found in the story of A. Green, so it seems that the new approach to the work of the writer as a representative of Russian expressionism, demonstrates its consistency and can be contrasted with the more traditional consideration of the authors prose as a super-textual unity.
The concepts «modern», «new» and «timely»
in the literary consciousness of the 1920s
Authors: Golubkov Sergei A.
Published: September 2021

In this article, we are talking about how the time of radical changes transforms the literary situation, changes the very content of modernity. This content includes a change in the types of artistic thinking, the interaction of style trends, the emergence of relevant topics, the change in the very forms of existence of a literary work, the change in the writer's status in society, the birth of new reader requests. Literary modernity is considered as a polyvector process, which includes various creative groups and writing communities. They offer their own innovations. The essence of the novelty of the next epoch can be expressed in an active dispute with the previous literary models. Contemporaries can put different content into the concept of a new one. So, in a highly political 1920-ies features of the new could suddenly acquire focus not on the ideological dominance of creativity and talent on the aesthetic quality of its products, to update the art forms (Serapion's brothers, Pass). Under the new one, we understood the variants of a fruitful synthesis of fiction and everyday life, realism and symbolism, realism and expressionism, point specifics and broad abstraction. The fate of individual genres (for example, the novel) was considered. The new could manifest itself in the very understanding of the timeliness (relevance) of a literary work. With the gradual introduction of strict regulation in the literary process, the understanding of such relevance changed (the theory of social order). The non-obviousness of the new (hidden timeliness) allows us to reevaluate the literature of the 1920s, to look at it from a century-old distance. The true innovations of this time are revealed.
Classics and modernity in the creative consciousness of Mikhail Bulgakov
Authors: Korablyov Alexander A.
Published: September 2021

The article presents the experience of analytical reading of M.A. Bulgakovs novel The Master and Margarita. The purpose of the work is to clarify the authors attitude to modern literature and to the forms of its implementation in the modern ideological context. Based on the structural and typological relationships, the author reveals the architectonic scheme of the novel, which determines the plot features of the composition. Concepts and activators of the plot action are the images of Bezdomny, Berlioz and the Master. They associatively focus on other characters comparable to them (writers, ideologists, mystics, etc.), as well as numerous prototypes, including V. Mayakovsky, S. Yesenin, M. Gorky, V. Lenin, etc. The prototypes of the novel are organized in such a way that they denote not only the contextual contour of the work, but also its conceptual certainty. The cryptological reading of the novel, taking into account the ratio of contour and conceptual prototypes, clarifies the authors attitude to modern phenomena and to modernity itself as a holistic phenomenon. The authors criterion of historical, social and cultural manifestations of modernity is the classical measure.
Semiotics as methodology and ontology
Authors: Nesterov Alexander Yu.
Published: September 2021

The article formulates the categories of general semiotics: sign, meaning, semiosis, layer and vector of semiosis. The purpose of the reasoning is to show the methodology of semiotic research as such, and general semiotics as ontology. The result of the reasoning is to demonstrate the semiotic circle of cognition and activity, which includes objects of perception as signs of sensory perception, objects of mind as signs of language and concepts of reason as complexly organized signs of reflexivity. The receptive and projective vectors of semiosis are introduced as direct cognition and reflexive activity respectively. The transition from cognition to activity - as intuition, organized via the models of aphorism, dialogue or system as philosophical inventions in the sense of I.I. Lapshin. The problem of the new that arises in intuition is considered as a question of the transformation of a specific semantic, syntactic or pragmatic rule in the layer of perception, mind or reason. The ontological thesis supported in the reasoning is that objects, subjects or concepts are not entities, but the rules of semiosis from the standpoint of general semiotics. By virtue of the fact that the conditions for the possibility of sign activity are the rules, by virtue of the rules constitute an objective unsigned meaning extracted by semiotic reflexivity, insofar as they objectively exist in the interaction of the environment and the subject.
Self-Identification of the character in the modernist novel by Lena Etlang «Pobeg kumaniki»
Authors: Poleva Elena A.
Published: September 2021

Lena Eltangs novel Pobeg kumaniki (Escape (Sprout) of the Brambles) is interpreted as a modern modernist prose that inherits the principles of the poetics of the stream of consciousness literature. The theoretical and methodological basis of the study was the work of A.A. Zhitenev, Ya.V. Soldatkina, N.T. Rymar, T.L. Rybalchenko.The self-identification of the main character in the novel by Lena Etlang Pobeg Kumaniki is complicated because of the absence of external supports of existence (home, communication with relatives, the name given to him at birth is not mentioned). Moras defines himself as a guest and a ubiquist, that is, a person who can exist in different conditions, but this does not answer the question Who am I?. The second thing that complicates self-identification is the inability to relate yourself to any particular Other (both in culture and in the environment), since situationally there are contradictory auto-associations with a variety of images from mythology and literature. The third challenge is the desire to combine not only different, but opposite (male and female, and depraved innocent, naive and wise, etc.). Pragmatism and the multidimensionality of identity, the desire to realize in my life more options (which gives the writing, creation of the text itself as others) that make the process of identity complex and unfinished. Another reason for the difficulty of identifying oneself is the limited epistemological possibilities and the inability of a person to take a position of non-necessity in order to see himself holistically. Eltang uses the Eastern parable of the cart, which illustrates the inability of a person to describe anything holistically, authentic to the essence of the described phenomenon. The main artistic principle of image-building in the novel is ambivalence, and the basic ideas are the multiplicity of consciousness and the incompleteness of a persons self-identification in the course of life.
Pandemic COVID-19 and measures to limit its spreading in Bulgaria: aftermaths and conclusions
Authors: Mantarova Anna I.
Published: September 2021

Since the beginning of 2020, the world has suddenly found itself in a unique situation - the spreading of the coronavirus has caused serious consequences in all areas and at all levels of society and required a radical change in peoples lives. The purpose of this article is, after presenting and analyzing the economic and social consequences of the spreading of COVID-19 and the measures taken by the government, to show that they have had an impact on all areas of the social system and that they will have a further reflection over time. The analysis used a sociological approach that interprets society as an integral system of interrelated and interdependent elements.The analysis showed that, especially in spring, instead of looking for options that balance safety and the ability to work, introducing fewer measures, but more carefully thought out, and strictly monitor their compliance, in fact, too many measures were taken. As the result, the control over their observance was weak. It is difficult to deny the lack of a systematic approach and thinking in perspective. The focus was exclusively on the results characterizing the spread of the coronavirus, ignoring the effects in other areas of public life, as well as in relation to diseases other than coronavirus. The epidemic highlighted problems and gaps in the countrys health care system and showed that there is a need to rethink the universality of market principles, whether they are applicable to health care system, and whether cost-effectiveness is the most important indicator for it, or the criteria for it effectiveness are different.
Discourse analysis of young people regional identity (based on empirical research executed in Togliatti)
Authors: Tsvetkova Irina V. , Ivanova Tatyana N.
Published: September 2021

Scientific approaches to social identity consider it as a dynamic structure, the result of social construction. The purpose of the article is a discursive analysis of the image of the city, which characterizes the features of the structure of the regional identity of young people. The novelty of the approach is to develop a methodology for analyzing the discourse of regional identity based on the study of the image of the city in the minds of young people. Materials and methods: The empirical base of the study includes essays written by young residents of Togliatti about their attitude to the city, its history, past, present and future (N=25). Text analysis involves the study of structures of discourse that characterize the perception of the youth of the citys history, the modern image of the city, and ideas about its future. The results of the research: The results of the discursive analysis revealed the specifics of the description of the image of Togliatti by young people in three time dimensions: in the past, present and future. The analysis of the image of the historical past of the city shows that it includes the contrast of the Stavropol stage to the period of the second half of the twentieth century, when Togliatti was formed. The Soviet past of Togliatti has a value for young people as an era of great achievements. The modern image of Togliatti is constructed as a contrast to this period; the authors demonstrate critical attitude to it. The image of the future city is presented as optimistic but uncertain. Discussion and conclusions: The development of discursive analysis is a promising area of scientific research of regional identity. The methodology makes it possible to identify and describe the dynamic structures of images that shape the attitude of young people to the region.
«Song about Volga» by V. Vysotsky: text and context
Authors: Perepelkin Mikhail A.
Published: September 2021

This article is devoted to the Song about Volga by V. Vysotsky and its place in the development of the Volga plot in Russian culture and literature. In order to indicate the context, the Volga works of I. Kondratiev and A. Navrotsky are studied; the main meanings fixed in the culture relating to the Volga in the late XIX and early XX centuries are revealed. Furthermore, we study the transformation of these meanings in the literature of the first decades of the twentieth century (A. Shiryaevets, Artem Vesely) and in the cinema (G. Alexandrovs feature film Volga-Volga). A special place is given to the studying of the story of A.N. Tolstoy Extraordinary Adventures on the Volga Steamer, in which a new version of the Volga plot, picked up and developed by other authors, appears and forms on the ruins of the former robber-Barge Haulers Volga myth. The historical review of the Volga texts concludes with a review of the revision of the image of the Volga and related subjects in the culture of the 1960s and 70s. The carried out historical and literary research becomes the basis for the analysis of the artistic structure of V. Vysotskys Songs about the Volga. This analysis allows us to conclude that, while restoring some of the connotations lost by the image of the Volga and the Volga plot, V. Vysotsky at the same time tried to create a text that would be as protected as possible from ideological and other restrictions, remaining alive any time and on condition of any ideology.
Molevich Yevgeny Fomich: Man of the Century
(for the 90th anniversary of the Scientist and Remarkable Man)
Authors: Avdoshina Natalya V. , Bocharov Vladislav Y.
Published: September 2021

Evgeniy Fomich Molevich turned 90 years old on the 25th of April 2021. He is an extraordinary man whose biography is a reflection of an entire era in the history of our country. The purpose of this article is to introduce the reader to human qualities and the main stages of life path, as well as scientific interests of a well-known scientist. There have been analyzed his sociological concept of the three-pronged structure of the modern sociological knowledge; the characteristic aspects of the approach regarding the labor activity analysis and its structure; the labor concept in a post-industrial society; the prospects for the construction of a modern society as a new social and information reality. Moreover, there has been make an emphasis on the applied aspects of E.F. Molevichs activities as the organizer of the sociological laboratory (1969), the director of the Research Institute of Social Technologies of Samara University (1995-2009) and the head of Sociology and Political Science Department. Conclusions concerning the reasons for widespread recognition in the scientific environment and successes in teaching and social activities have been drawn.
Employment transformation in digital capitalism: myths and realities of the social consequences of the global economy digitalization
Authors: Arseienko Anatoliy G.
Published: September 2021

The article is devoted to the study of the social consequences of the employment transformation in the world of capital in the context of the modern expansion of global capitalism and the digitalization of the global economy. Particular attention is paid to proving the inconsistency of the current mythologization of the digital economy in order to cover up the anti-labor orientation of various forms of non-standard, informal employment, which has become widespread in all three worlds of the modern world-system within the framework of digital capitalism. At the center of the analysis of the digital economy impact on the workers socio-economic situation is the digitalization of the world of work and social and labor relations in the United States, that serve as a role model throughout the world, especially in the economically developed countries of the global North. The digitalization of labor in the Golden Billion countries, as well as in the Third World countries with a transition economy instead of the promised reduction of the contradictions between labor and capital led them to an even greater exacerbation and gave rise to a new type of social inequality digital inequality both inside all countries and between them. The author concludes that there has been a significant increase in the labor exploitation intensification as a result of the digital revolution and the need to search for and introduce new forms of world order under the slogan of the alterglobalists social movement People are higher than profits.
Cardiac Manifestation among Patients with Hypothyroidism - A Cross-Sectional Study in North Karnataka
Authors: Lakshetty Swetha Rajshekar , Devru Nandini
Published: September 2021

BACKGROUND Hypothyroidism is the second most common endocrinopathy next to diabetes mellitus (DM). Hypothyroidism is associated with increased cardiovascular mortality and morbidity. Cardiovascular complications are some of the most profound, reproducible and reversible clinical findings associated with thyroid disease1 . Hence this study was undertaken to assess the cardiac dysfunction among patients with hypothyroidism by electrocardiogram (ECG) and echocardiogram (ECHO) so as to provide a proper treatment guideline even among milder cases. METHODS This was a cross sectional study carried among 50 new patients of hypothyroidism who presented to Navodaya Hospital, Raichur during 2015 to 2017. They were clinically evaluated and underwent relevant investigations, including thyroid profile estimation, cardiac evaluation using ECG and 2D ECHO. RESULTS Most cases fell in the age group of 31 - 40 years. There was an overall female preponderance (76 %) over all age groups with mean age of 42.02 years. Goiter was found in 8 % of patients, bradycardia and hypertension was seen in 30 % and 22 % respectively. Central nervous system (CNS) examination revealed delayed ankle jerk in 40 % followed by hoarseness of voice in 38 % of patients. Lipid analysis showed increase of total cholesterol (TC), low density lipoprotein (LDL), very low-density lipoprotein (VLDL), triglycerides (TGL) and decrease of highdensity lipoprotein (HDL). Normal ECG was found in 26 % of patients. Bradycardia was most common finding seen in 30 % (15) of patients. 24 % (12) of patients exhibited low voltage complexes. While, 46 % cases showed normal ECHO findings. 24 % of cases presented with pericardial effusion. 18 % cases presented with diastolic dysfunction among which majority were mild. None of the cases had severe diastolic dysfunction. Only a meagre 10 % cases showed intraventricular septum (IVS) thickness. CONCLUSIONS Pericardial effusion was seen among 24 % of patients while diastolic dysfunction was seen in 18 % patients. Thus, any unexplained pericardial effusion should be screened for hypothyroidism. KEYWORDS Hypothyroidism, Cardiac Dysfunction, 2D ECHO, ECG, Thyroid Stimulating Hormone (TSH)
Validation and Verification of Cavitation in Microchannels by using an Open Source Computational Tool
Authors: ÖZKAZANÇ Gökçe , ÜNLÜSOY Levent , ERDEM Emine Yegan
Published: September 2021

Cavitation is mostly unwanted in applications due to its unpredictable and distorting effect on fluid flow. On the other hand, its modelling is expensive in terms of time and computational power in general. Regarding this a tendency for using an open source software such as OpenFOAM is emerging as a promising tool for both predicting and analyzing cavity formation. With this tool, an effective reduction in license expenses is obtained. In this study, validation and verification of an OpenFOAM solver is investigated for cavitation in microchannels. Experiments are carried out as well for comparison with computational results. During the experiments, fluorescent particles were introduced in the flow and cavity formation was observed under a fluorescent camera. Therefore, motion of the cavity was also efficiently captured. Overall, computational and experimental results are compared and contrasted to investigate the capability of OpenFoam for the chosen conditions.
Investigation of the effects on dose calculations of correction-based algorithms in different tissue medium
Authors: ARAS Serhat
Published: September 2021

The aim of this study is to determine the effects of correction-based algorithms on dose distributions in the inhomogeneous medium and dosimetric parameters depending on the algorithms preferred in breast and lung treatment plans. In the treatment planning system (TPS) in which the Pencil Beam Convolution (PBC) dose calculation algorithm is used, dose calculations were performed in different correction-based algorithms Modified Batho and Equivalent Tissue-Air Ratio (ETAR) for soft tissue, bone and air medium. Rectilinear virtual phantoms were created in TPS for soft tissue, bone and air materials, and deep dose values and dose distribution profiles at lateral depth were obtained. Intensity modulated radiotherapy (IMRT) treatment planning technique was applied to 20 patients with breast and lung cancer diagnosis on computed tomography (CT) sections, and dose calculations were performed. Different dosimetric parameters obtained within the target volume were calculated. Although the effects of correction-based algorithms on dose values depending on the depth and dose distribution profiles in lateral depth were calculated below 1% in dose calculations performed on soft tissue virtual phantom, dose profiles were obtained as approximately 20% in bone and air medium. It was concluded that correction-based algorithms in the different inhomogeneous mediums have a significant effect on the dose values calculated in TPS.
Surveillance analysis and microbiological profiles of nosocomial infections in a palliative care center
Authors: AKDOĞAN Doğan
Published: September 2021

Objective: The growing geriatric population and increasing prevalence rates of chronic diseases increase the need for palliative care globally. Despite the wide availability of palliative care units in several countries, they have been founded in our country recently. This study aimed to contribute to the development of appropriate treatment protocols by determining the causes of hospitalizations, comorbidities, infection rates, and causative microorganisms in a palliative care center.

Material and Method: A total of 457 patients admitted to palliative care were evaluated. Blood cultures were taken from the patients suspected to have developed nosocomial infections. Samples for cultures were taken from the foci that were thought to be the origin of infection. Identification of isolates was performed using automated systems and standard manual methods. The numbers of patients and patient days, and the numbers and rates of nosocomial infections were retrieved from the infection control unit data records and were analyzed. The rates and incidences of nosocomial infections in our hospital and the palliative care unit were calculated.

Results: Of the patients, 51% were men and 49% were women. The mean age was 72±12.6 years. Nosocomial infection rates were 6.3% in 2019, 9.1% in 2020, and 3.3% in the first six months of 2021. Urinary system infections ranked first with a rate of 58.6%. The most common cause of hospital admissions was malignancy with a rate of 25.9%. The most commonly isolated microorganism was Klebsiella spp with a rate of 27.5%.

Conclusion: Palliative care is a multidisciplinary practice requiring strong coordination and collaboration. Palliative care aims to improve symptoms and the quality of life of patients. Our study has contributed to developing practical solutions by documenting prognostic factors, infections, causative microorganisms, and issues experienced in palliative care patients.
ЗІСТАВНИЙ АНАЛІЗ КОНЦЕПТУАЛЬНО-ФРЕЙМОВОГО КОНСТРУЮВАННЯ ЖІНОЧОЇ ІДЕНТИЧНОСТІ (НА МАТЕРІАЛІ РОМАНУ Ш. БРОНТЕ «ДЖЕЙН ЕЙР»)
Authors: ПАРАХОНЬКО Людмила В'ячеславівна
Published: September 2021

Мета статті — провести зіставний аналіз концептуально-фреймового конструювання жіночої ідентичності на матеріалі роману Ш. Бронте «Джейн Ейр». Об’єкт аналізу — акцентування концептуально-когнітивного фрейму «Ідентичність жінки» в англійській і російській лінгвокультурах. Предмет аналізу — зіставний аналіз оригінального і перекладеного текстів. У роботі використано методи контрастивного та контекстуального аналізу. Результатом проведеного дослідження є розгляд амбівалентності у ставленні до жіночої ідентичності, яку сприймають як закріплення жіночого індивіда за певною особистісною і соціальною позицією, підкреслена важливість тавтологічних і плеонастичних компонентів, що виражають певні смисли, виявлено проблематичний аспект дослідження, окреслено перспективи рішень. Висновки. Переклад роману «Джейн Ейр» відображає мовну свідомість І. І. Введенського, яка відрізняється від досвіду і знань автора оригінального твору. Це дає змогу ідентифікувати мовну особистість самого перекладача, що вважається неприйнятним, бо переклад спотворює розуміння жіночої суті, домисел перекладача частково нівелює задум автора. Практичне застосування результатів роботи полягає в тому, що вони можуть знайти використання в курсах з лінгвокультурології, теорії перекладу, у практиці перекладацької діяльності.
КОДОВІ ПРОСТОРИ ТА ЛІНГВОКУЛЬТУРНІ КОДИ ЯК СПОСІБ ОРГАНІЗАЦІЇ КУЛЬТУРНОЇ ІНФОРМАЦІЇ (на матеріалі фразеології російських говірок Півдня України)
Authors: АРЕФЬЄВА Наталія Георгіївна
Published: September 2021

Мета статті полягає у визначенні методологічного апарату, який сприяє виявленню та опису етно- та лінгвокультурного змісту мовних одиниць на прикладі російської діалектної фраземіки Півдня України. Предмет дослідження становлять кодові простори й лінгвокультурні коди, планом вираження яких є культурно значущі мовні одиниці, зокрема фразеологізми, що існують у російських говірках Півдня України. Методологічною основою дослідження стали сучасні розробки й основні положення лінгвосеміотики, лінгвокультурології, етнолінгвістики, концептології, діалектології, фразеології. Як спосіб виявлення, систематизації та подальшого опису культурного знання запропоновано класифікацію, яка передбачає виокремлення трьох кодових просторів: антропного, природного та ірраціонального — і лінгвокультурних кодів, що їх наповнюють. Класифікацію проілюстровано конкретними прикладами; відзначено перетини лінгвокультурних кодів і кодових просторів. Результатом дослідження стали висновки, згідно з якими фразеологічна, мовна, концептуальна картини світу можуть бути реконструйовані за допомогою кодових просторів і лінгвокультурних кодів, що їх наповнюють. Складовими лінгвокультурних кодів є знаки культури, закріплені в мові: архетипи, концепти, стереотипи, еталони, символи.
Resenha - SANTOS, Boaventura de Sousa A cruel pedagogia do vírus [recurso eletrônico]. 1. ed. São Paulo: Boitempo, 2020, 47p
Authors: Dias Marly de Jesus Sá
Published: September 2021

O livro A Cruel Pedagogia do Vírus foi escrito pelo doutor em Sociologia do Direito pela Universidade Yale, professor catedrático jubilado da Faculdade de Economia da Universidade de Coimbra e Distinguished Legal Scholar da Universidade de Wisconsin-Madison Boaventura de Sousa Santos, no ano de 2020. Publicou variados trabalhos, entre os quais: A crítica da razão indolente: contra o desperdício da experiência. São Paulo: Cortez, 2000; Reinventar a democracia. Lisboa: Gradiva, 1998; Pela Mão de Alice: o social e o político na pós-modernidade, Porto: Afrontamento, 1994; O direito dos oprimidos. São Paulo: Cortez, 2014; A gramática do tempo: para uma nova cultura política. Porto: Afrontamento, 2006. Também publicado no Brasil, São Paulo: Editora Cortez, 2006.
PROGRAMA NACIONAL DE HABITAÇÃO RURAL E CONDIÇÕES DE MORADIA EM PEQUENAS CIDADES NA AMAZÔNIA PARAENSE
Authors: Silva Walkiria Maria Sousa da , Santana Joana Valente , Melo Katia Maria dos Santos , Soares Pedro Paulo de Miranda Araujo
Published: September 2021

O artigo analisa o direito à moradia rural em pequenos municípios paraenses (Abaetetuba, Santa Izabel do Pará e Soure), por meio do Programa Nacional de Habitação Rural (PNHR), considerando aspectos socioeconômicos das famílias. A pesquisa é orientada pelo materialismo histórico e dialético, realizando levantamento bibliográfico, documental e de campo, com formulários e entrevistas semiestruturadas. Os resultados mostram que o PNHR oferece o acesso à nova casa; o sentimento de segurança; a existência de banheiro interno; os serviços de saúde e de educação. Por outro lado, as famílias relatam problemas de infraestrutura da casa e do entorno, além da dificuldade de pagamento da mensalidade. Conclui que o PNHR desconsidera as particularidades regionais, como a necessidade de compartimentos amplos de cozinha e pátio, com vistas à preservação da sociabilidade do modo de vida rural amazônico.NATIONAL RURAL HOUSING PROGRAM AND HOUSING CONDITIONS IN SMALL CITIES IN THE AMAZONAbstractThe article analyzes the right to housing in rural areas of small cities in Pará, Brazil (Abaetetuba, Santa Izabel do Pará and Soure), considering the socioeconomic characteristics of the beneficiaries of the National Rural Housing Program (PNHR). It draws upon the historical dialectical materialism and relies on bibliographic, documentary, and field surveys, when the authors conducted interviews. Data suggests the access to the new house, the feeling of security, the inside bathroom, the presence health and education services are positive aspects of the PNHR. Moreover, the downsides are the lack of urban infrastructure, poor quality of house construction, and difficulties in affording the monthly fee. It concludes the PNHR disregards regional particularities as the need for large kitchen and patio compartments, in order to preserve the sociability of the Amazonian rural way of life.Keywords: Rural housing in Pará. Right to housing. Housing policy. National Rural Housing Program.
​​Effect of Environmental Heavy Metal Pollution on Metabolic Profile of Buffaloes in Ludhiana
Authors: Yeotikar Pranesh V. , Nayyar Shashi , Singh Chanchal , Mukhopadhyay C.S. , Jindal Rajesh , Chhabra Sushma
Published: September 2021

Background: The industrial hub of Punjab, Ludhiana is polluted with heavy metals. The dairy animals experience stress due to pollution of heavy metals as well as the hot summer season. The stressors lead to disturbance in metabolic profile and affect milk production. The present study aimed at evaluation of detrimental effect of environmental heavy metal pollution on the metabolic profile of buffaloes during summer and winter seasons in Ludhiana district of Punjab, India. A total of 100 buffaloes were randomly selected from heavy metal exposed (n=60) and control area (n=40) during summer and winter seasons. Methods: The location of the experimental area surveyed on the basis of levels of heavy metals. The dairy farms are located in and around Ludhiana, Punjab were identified with levels of heavy metal above the permissible limits (FSSAI, 2010) viz. Chromium-0.05 µg /ml; Nickel-0.02 µg /ml; Arsenic-0.05 µg /ml and Lead -0.05µg /ml. The plasma samples were analyzed for metabolic profile. The water levels of heavy metals were below the permissible limits; therefore, it was taken as uncontaminated or control area. Result: Buffaloes of heavy metal exposed areas exhibited significantly (P less than 0.05) higher levels of glucose, total cholesterol, triglycerides, BUN, creatinine, AST, ALT, GGT, ALP and CK levels as compared to control area. A significant (P less than 0.05) decrease was observed in plasma total protein, albumin, A:G ratio, BUN: creatinine ratio in the buffaloes of exposed area as compared to the control area. However, significantly (P less than 0.05) higher levels of plasma glucose, BUN, creatinine, AST, ALT, GGT, ALP and CK levels were observed during summer as compared to winter season in both exposed and control areas. Significantly (P less than 0.05) decreased levels of plasma total cholesterol, triglycerides, total protein, albumin and BUN: Creatinine ratio were observed in the buffaloes during summer as compared to winter in both exposed and control areas. The Cr, Ni, As and Pb levels showed highly significant (P less than 0.01) positive correlation with plasma levels of glucose, total cholesterol, creatinine, ALT, AST, CK and GGT. Highly significant positive relationship (P less than 0.01) was observed among plasma levels of glucose, total cholesterol, creatinine, BUN, ALT, AST, ALP, CK and GGT whereas, plasma BUN had highly significant (P less than 0.01) negative correlation with plasma total protein and A:G ratio considering both the areas together. Plasma levels of total protein showed significant (P less than 0.01) negative correlation with all other metabolic profile constituents of both control and heavy metal exposed areas. Thus it may be concluded that the metabolic disturbance in heavy metal exposed buffaloes may have been mediated by heavy metal pollution.
PCR-RFLP Analysis of Single Nucleotide Polymorphism (SNP) C-2402T at the Promoter Region of Prolactin Gene and its Association with Positively Correlated Production Traits in White Leghorn Chicken
Authors: Manoharan Azhaguraja , Sankaralingam S. , Anitha P. , Chacko Binoj , Aravindakshan T.V.
Published: September 2021

Background: The avian prolactin gene is highly conserved, located on chromosome number 2 and most sequence polymorphisms occurs in the 5’ flanking region, 3’ flanking region, and the coding region of signal peptide. The present study was aimed at the identification of SNP C-2402T of prolactin gene and its association with production traits in White Leghorn chicken. Methods: A total of 200 birds of White Leghorn were selected from All India Co-ordinated Research Project on Poultry improvement (AICRP) farm, Mannuthy. Genomic DNA was isolated from venous blood. Polymerase chain reaction (PCR) followed by restriction fragment length polymorphism (RFLP) analysis was done to identify the SNP C-2402T of prolactin gene. Result: All the birds were observed with the same genotype CC and the frequency of the C allele was one.
A National Reassessment: Exploring Variables that Predispose People with Disabilities to Vocational Rehabilitation Acceptance
Authors: Wilson Keith B. , Gines Jason E.
Published: September 2021

Vocational rehabilitation (VR) acceptance has been explored by many research teams over the last 30 years. However, none of the prior studies explored the multitude of demographic variables that may influence VR acceptance and the possible interactions of those variables with VR acceptance. Extrapolating demographic variables from the national RSA-911 database of persons who sought vocational rehabilitation services, a Chi-squared Automatic Interaction Detector (CHAID) and the backwards elimination method of entry were used as the test statistic. Race, education, monthly public assistance at application, and marital status, respectively, were significantly correlated to VR acceptance. Implications for VR counselors and educators are discussed.
Examining Sexual Orientation Differences in the Utilization of the Human Papillomavirus Vaccine, Human Papillomavirus Test, and Cervical Papanicolaou Test in Allegheny County, Pennsylvania
Authors: Corey Stephanie L. , Haggerty Catherine L. , Soliman Amr S. , Coulter Robert W. S.
Published: September 2021

Despite sexual minorities' (SMs) increased risk for contracting human papillomavirus (HPV) and developing related cancers compared to their heterosexual peers, we know little about SM disparities in uptake of HPV vaccines and routine screenings. Therefore, this study examined sexuality differences in HPV preventive interventions and related screenings. From 2015 to 2016, Pennsylvania's Allegheny County Health Department commissioned a health survey of 9,026 adults in their catchment area using probability-based sampling. Multivariable models tested differences by sexual identity separately for cisgender men and women (heterosexual versus gay/lesbian, bisexual, and other) for lifetime receipt of HPV vaccine and number of HPV vaccines. Among women, we examined sexuality differences in HPV and cervical Pap tests, adjusting for age, race/ethnicity, education, marital status, and income. No differences in prevention utilization emerged when comparing heterosexual women to all SM women. However, exploratory analyses comparing heterosexual women to subgroups of SM women found lesbians had higher odds (adjusted odds ratio [AOR] = 5.27; 95% confidence interval [CI] = 1.15–24.09) of never receiving an HPV vaccine. Women who reported their sexuality as “other” had higher odds (AOR = 5.65; 95% CI = 1.03–31.02) of never receiving a cervical Pap test compared to heterosexual women. “Other” women had higher odds (AOR = 19.80; 95% CI = 1.64–239.16) of never receiving a cervical Pap test when compared to heterosexual women receiving one within the recommended screening guidelines. SM men's utilization was not significantly different from heterosexual men, though vaccination uptake for both groups was low. These findings highlight the need for additional public health surveillance to understand cancer prevention utilization among this underserved population.
The Role of LGBTQ Identity Pride in the Associations among Discrimination, Social Support, and Depression in a Sample of LGBTQ Adolescents
Authors: Chang Cindy J. , Feinstein Brian A. , Meanley Steven , Flores Dalmacio D. , Watson Ryan J.
Published: September 2021

The current study examined the role of LGBTQ identity pride in the associations among discrimination, social support, and depressive symptoms in a sample of LGBTQ youth. As part of a larger study, 13,440 LGBTQ youth completed a survey assessing depressive symptoms, past-year bullying, family rejection, general and LGBTQ-specific teacher support, general and LGBTQ-specific family support, and LGBTQ identity pride. Findings showed that greater bullying and family rejection were associated with lower LGBTQ identity pride and, in turn, greater depression. Conversely, greater general and LGBTQ-specific teacher support and greater general and LGBTQ-specific family support were associated with greater LGBTQ identity pride and, in turn, lower depression. All of the indirect effects were significant when the predictors were examined in separate models and most remained significant when the predictors were examined simultaneously. LGBTQ identity pride may be a mechanism linking discrimination and social support to depression among LGBTQ youth.
The Effects of Social Location and Situational Factors on Young Women’s Disclosure of Intimate Partner Violence Across Relationships
Authors: Kennedy Angie C. , Bybee Deborah , Adams Adrienne E. , Moylan Carrie A. , Prock Kristen A.
Published: September 2021

The goal of the study was to examine disclosure of physical and sexual intimate partner violence (IPV) victimization across abusive relationships within a sociodemographically diverse sample of young women. We recruited 283 participants, ages 18 to 24, from a university, a 2-year college, and community sites serving low-income young women, and assessed physical and sexual IPV victimization, and related disclosure, across each of their abusive relationships (415 total). We used multilevel modeling to examine the effects of social location and situational factors on the odds of any disclosure of abuse during first relationships and across relationships. The rate of physical IPV disclosure was 50%, vs. 29% for sexual IPV. Multilevel model results indicated setting, IPV type, high frequency sexual IPV, and fear were significantly related to any disclosure.