bluuebunny/crossref_metadata_2025 huggingface dataset:
The frequency of detection of anti-HBc in blood donors from four regions of Russia
Authors: Abakarov R. R. , Tikhomirov D. S. , Tupoleva T. A. , Ignatova E. N. , Kulikov S. M. , Garmaeva T. Ts. , Tkachenko L. L. , Seitibragimov F. I. , Gilmutdinov R. G. , Mostovaya N. A. , Makedonskaya O. G. , Romashkina T. V. , Davydova L. E. , Gerasimova V. V. , Gaponova T. V.
Published: September 2021

Introduction. Occult hepatitis B virus (HBV) revelation in HBV nuclear antigen testing is of particular importance to prevent transfusion infection.

Aim — the identification of factors affecting the anti-HBc detection rate in donated transfusable blood components from different regions of Russia.

Materials and methods. A cohort screening single-stage epidemiological study was conducted with 2,000 donor blood samples, 500 samples per each of four regions of the country, the Republics of Crimea (Simferopol) and Sakha (Yakutia), the cities of Saransk and Orenburg. Data on 968 blood samples from the National Research Center for Hematology’s donor bank were used as reference. The testing targeted HBV nuclear antigen antibodies. Positive donated blood samples were additionally tested for IgM and virus surface antigen antibodies using Abbott and Vector-Best commercial reagent kits.

Results. Donor demographic profiles differed insignificantly across members of the Russian Federation. Males predominated among the donors (69.6 %). Anti-HBc was detected in 219 of 2,000 samples examined (10.9 %). The donor blood sample anti-HBc detection rate ranged from 6.0 to 21.6 %, depending on the region. Anti-HBc-positive proportions in Orenburg, Crimea, Mordovia and Sakha comprised 8.2, 8.0, 6.0 and 21.6 %, respectively (p < 0.01). First-time donors had anti-HBc in 8.06, regular donors — in 11.29 % cases. The anti-HBc detection rate varied with donor’s age, being zero or near 1 % in 20-yo or younger people. Acute HBV antibodies had zero rate in Orenburg at zero or low-titre (< 100 mIU/mL) protective antibodies; 31 total samples, 15 low-titre and 16 negative for protective antibodies. In Simferopol, acute phase antibodies were negative in 7 blood samples containing high-titre protective antibodies (> 100 mIU/mL) and in 5.0 % samples with their low or zero levels. In Yakutian donors, acute phase antibodies were revealed only at protective antibodies negative. In Saransk, this marker was equal-proportion at zero and high-titre protective antibodies (3.3 % each).

Conclusion. Transfusion component procurement from younger donors should be prioritised as enhancing haemotransfusion viral safety. Positive occult HBV tests were less common in regions with low HBV incidence.
National clinical recommendations for the diagnosis and treatment of mastocytosis
Authors: Melikyan A. L. , Subortseva I. N. , Shuvaev V. A. , Morozova E. V. , Lukina K. A. , Artemieva S. I. , Livov A. N. , Baykov V. V. , Vinogradova O. Yu. , Galstyan G. M. , Gilyazitdinova E. A. , Dvirnyk V. N. , Zhukova O. V. , Kovrigina A. M. , Kohno A. V. , Kuzmina L. A. , Lomaia E. G. , Lukina E. A. , Martynkevich I. S. , Mitina T. A. , Potekaev N. N. , Sudarikov A. B. , Shatokhina E. A. , Frigo N. V. , Savchenko V. G.
Published: September 2021

Introduction. Recommendations cover the current state of diagnosis and treatment of mastocytosis.

Aim — а consolidation of the Russian experts’ opinion on treatment for adult mastocytosis.

Main findings. The recommendations have been developed taking into account foreign literature, national experience and world clinical evidence on therapy for systemic and cutaneous mastocytoses, mast cell leukaemia and other mastocytosis forms. The significance of bone marrow and peripheral blood molecular genetic testing for the presence of KITD816V gene variants is demonstrated. The treatment regimens described are based on midostaurin, imatinib, cladribine, hydroxycarbamide, interferon alfa and haematopoietic stem cell transplantation. Prognosis in different forms of mastocytosis is provided.
Quality Assurance in Nigeria’s Education System: Prospect and Challenges
Authors: Usman Yunusa Dangara , Chinyere Madudili Geraldine
Published: September 2021

The study was conducted with the aim of establishing the relevance and challenges affecting quality assurance in Nigerian education system. Secondary data analysis methodology was adopted for the study. To easily achieve the objectives, the concept of quality assurance, strategies for building quality assurance into the education system and parameters for measuring quality assurance and challenges were discussed. The study identified some challenges affecting quality assurance to include shortage of funds, insecurity, policy inconsistency, and lack of regular training of staff etc. The paper concludes that since the essence of education is to make an individual useful quality assurance strategies should be monitored and evaluated   on regular basis in order to improve the quality of the educational system in Nigeria. The study therefore recommends amongst others improved funding of the education sector, regular training and retraining of staff and provision of adequate security for learning environment in the country as a way forward.
Improving Mathematics Learning Outcomes With The Application of Cooperative Learning Model For XII MIPA of SMAN 8 Takalar
Authors: Fatwa Inayanti , Harjuna Hariani
Published: September 2021

This research is a Classroom Action Research (CAR) which aims to determine the improvement of mathematics learning outcomes with specialization by applying the cooperative learning model of class XII MIPA students at SMAN 8 Takalar. From the results of this study, it can be seen the percentage of classical completeness from the initial test (pre-test), cycle I, and cycle II. In the initial test before getting the cooperative learning model treatment on specialization mathematics subjects, the average score of the student learning outcomes test reached 60.21. Furthermore, in the first cycle learning outcomes test increased to 71.39. This means an increase of 11.18. Then in the second cycle of learning outcomes test, the average value of the class reached 78.12. This means that there is an increase of 6.73 from cycle I. Before the action treatment was held, the number of students who achieved the minimum completeness criteria indicator (KKM) namely ≥72 was 14 students or 42.42%, while seen from the activities of the first cycle the number of students who achieve the KKM score increased to 20 students or 60.60%. The increase was also seen in the second cycle, the number of students who achieved the KKM score was 26 students or 78.78%.
Review: Sustainable Water Resources Engineering and Management; Nigerian Perspective
Authors: Gana A. J , Amodu M. F.
Published: September 2021

Water resources sustainability is essential to life because all living things and some non-living things need it to complete their processes. The water usage is rising, hence pressure on the availability, and some instances rose to crisis level. These pressures were due to population growth, increases in irrigated land, deforestation, soil and land degradation, and wastages. Engineering is one of the majors’ components in tackling water resources sustainability. Therefore, this paper reviews the general concepts of sustainable water resources from an engineering and management perspective. The method adopted to realize the aim of the research was a thorough literature review. Engineering has three sub-components, these are Ecological, Economic, and social sustainability. Failure in one of these sub-components is a failure of the component. The literature revealed that Water resources sustainability is a multifaceted discipline therefore, engineering discipline alone would not solve it. However, this paper proffered some recommendations and the way forward. These recommendations are the steps required at the watersheds level, the engineering strategies aspects, and the management strategy. It concluded that a holistic approach where all shareholders will be involved is an ideal approach.
Promoter Analysis of Public Water Supply Facilities in Southwest Nigeria
Authors: Iji J. O
Published: September 2021

Sustainable water supply system is a necessity in growing communities. This study identified Governments, NGO’s (Donor and Joint Partnership), and Private Sector (Communities) as the three major promoters of public water supply facilities in a developing country like Nigeria. Secondary data retrieved from the National Water Supply and Sanitation database in the six States of South-West Nigeria was used for the study. The Kruskal-Wallis Test was adopted for the data analysis and description which showed an indication of performance mean rank of promoters. The results indicated that the promoters with highest percentages of operational facilities in the six States are: Communities (ranging between 89% and 100%); and NGO’s which comprises of both Joint Partnership between two or more promoters and Donor (ranging between 75% and 100%, and 56%) respectively. The federal government has the highest percentage of non-operational facilities in five of the six States ranging between 46% and 73%. In the other remaining State (Osun), LGA (Local Government Authority) had the highest percentage of non-operational facilities of 34.1%. There were more operational facilities in 50% of the States compared to the non-operational. The non-operational facilities are grounded due to broken down machines, poor construction or lack of maintenance and supervision.
Evaluation of Locational and Environmental Effects of Religious Centres on Adjoining Development in Ibadan, Nigeria
Authors: Odunola O. O.
Published: September 2021

This study assesses locational and environmental effects of religious centres on adjourning development in Ibadan South-East Local Government, Oyo State, Nigeria. Primary and secondary data were utilized. Geographic coordinates of religious centres were collected using GPS for a location-based mapping and nearest neighbour analysis in ArcGIS 10.3. A Multi-stage sampling technique was employed and systematic sampling procedure was used to administered 210 copies of questionnaires to respondents. The data were analysed using descriptive statistics which were frequency distribution and absolute mean in SPSS. Results showed that the nearest neighbour index (Rn) is 0.01 with critical value of <-2.58, p-value is 0.704138 and the nearest neighbour ratio equals 0.61799. Most religious centres were located without planning development permits and therefore are restricted by law to operate in the residential areas they were sited. Other key findings were based on three indices that were developed which are Proliferation Influencing Index (PII), Environmental Impact Index (EII) and Precaution Measures Index (PMI). The highest PII of 3.82 indicated that the proliferation of religious centres is majorly caused by “beliefs and practices”. An EII of 4.03 showed that environmental impact is highly due to “non-compliance with conditions of existing consents already in place” while “payment of fine by defaulters” with the highest PMI of 3.85 is the most used control measure. This study concludes that religious centres have been encouraged in residential areas by use of fines as against the enforcement of planning regulations as contained appropriately in urban and planning regional law.
Dynamic Routing and Spectrum Assignment based on the Availability of Consecutive Sub-channels in Flexible-grid Optical Networks
Authors: Lohani Varsha
Published: September 2021

Variable bandwidth channels can be created in Flexible Grid Optical Networks using Optical Orthogonal Frequency Division Multiplexing (O-OFDM). This allows more efficient use of spectrum by allocating integral multiple of basic bandwidth slot to the lightpath requests. In these networks, the constraint of keeping all the allocated slots together is added when deciding the routes for the requests. This constraint is called the contiguity constraint, which makes the routing and spectrum arrangement algorithms more challenging. In any network, the lightpath requests will arrive and depart dynamically and invariably lead to spectrum fragmentation. Hence network will have to reduce the maximum possible utilization as well as increased blocking probability. In this paper, we have presented an improvised Routing and Spectrum Assignment (RSA) algorithm using consecutive spectrum slots that leads to lesser fragmentation. It is evident from the results that the presented RSA algorithm uses adaptive parameters to reduce the blocking probability and fragmentation compared to the other algorithms reported in the recent past.
Gobierno de Gabinete
Authors: Portillo Arévalo Melvin Giovanni
Published: September 2021

OBJETIVO: presentar un análisis crítico con la finalidad de realizar conclusiones, aportes y criterios del libro “El Gobierno de Gabinete” del jurista Diego Valadez, que tiende a explicar la propuestas del nuevo sistema de gobierno que se propone para México. MÉTODO: el método utilizado fue selectivo debido a que se seleccionó la bibliografía a estudiar, correspondiente al tema “Gobierno de Gabinete” del del autor constitucionalista Diego Valadez. RESULTADOS: la reforma del Estado, especialmente de las libertades y responsabilidades de quienes nos gobiernan, así como entender que una democracia no sólo son derechos de los ciudadanos y libertades políticas sino que también debe  existir una responsabilidad de los gobernantes, considero que son aspectos  relevantes  del tema. CONCLUSIÓN: es una etapa  que se está  refiriendo a los gobernantes y no sólo a los gobernados, ya que ahora no sólo se habla del derecho de elegir a nuestras autoridades sino que también cómo podemos pedirle a los gobernantes algún tipo de respuestas cuando  incurren  en contra  de una norma constitucional o contra los intereses generales  y el bien común. Para lo anterior, es necesario un análisis de los representantes del pueblo, construyendo nuevas instituciones que permitan que los electores puedan ratificar el voto con dignidad y eficacia; pero también poder negarlo cuando esa representación no responde a los intereses del pueblo.
Interceptaciones telefónicas y la vulneración de derechos fundamentales
Authors: Ruiz Villeda Meylin Surany
Published: September 2021

OBJETIVOS: presentar el estudio interceptaciones telefónicas y la vulneración de derechos fundamentales. de lo que es la delincuencia organizada, la evolución que la misma ha manifestado, las formas en que el Estado de Guatemala, ha adecuado su legislación para poder contrarrestar ese flagelo, por medio de la implementación de Métodos Especiales de Investigación, específicamente el relacionado a las interceptaciones telefónicas. MÉTODO: se utilizó el método analítico, inductivo, bibliográfica, jurídica, y documental. RESULTADOS: para la aplicación o ejecución de las Interceptaciones Telefónicas, la Policía Nacional Civil integrará un equipo especial de técnicos y seleccionará al personal policial que se va a encargar de la ejecución de las interceptaciones de las comunicaciones; el fiscal encargado del caso, posteriormente a realizar una evaluación del informe de la investigación preliminar y determinar la necesidad de la utilización de ese método especial, debiendo realizar la solicitud de autorización al juez competente. CONCLUSIÓN: las interceptaciones telefónicas es un método especial que está regulado en la Ley de delincuencia organizada, que si bien es cierto limita un derecho fundamental como lo es la secretividad de las comunicaciones, también es importante afirmar que tiene formas y procedimientos que deben de cumplirse para la validez y legalidad de la obtención de la información, siendo una herramienta eficaz y sobre todo científica que nos permite el esclarecimiento de la verdad.
La programación neurolingüística en los directivos de las organizaciones educativas peruanas en tiempos de pandemia
Authors: Romero Chacín Jorge Luis , Romero Parra Rosario Mireya , Barboza Arenas Luis Andres
Published: September 2021

La PNL se proyecta como una herramienta de perfeccionamiento colectivo e individual en el marco de la excelencia, que favorece la humanización y sensibilidad de este mundo neurotizado por las diferentes barreras comunicacionales y paradigmas culturales y sociales; con el objetivo de optimizar nuestras esferas de actuación. La finalidad del presente artículo fue analizar el conocimiento acerca de la Programación Neurolingüística que posee el personal directivo de las escuelas de Educación Básica del distrito los olivos de la provincia de lima, Perú en los actuales tiempos de pandemia. El estudio se fundamentó con los planteamientos teóricos de Douat (2017), Deminco (2019), Muñoz (2019), Redford (2017), Romero et al. (2015), entre otros. Se utilizó una metodología descriptiva con diseño no experimental. La muestra estuvo constituida por 58 sujetos, a los cuales se les aplicó un cuestionario. Los resultados muestran que los directivos poseen un mediano conocimiento de la PNL y con respecto a la comunicación, la media aritmética es de 0,188 categorizándose en muy baja, según el baremo establecido, lo cual indica que el personal directivo de los colegios nacionales de educación primaria del distrito Los Olivos de la provincia de Lima, poseen muy bajo conocimiento acerca de la comunicación, resultando un aspecto negativo en cuanto al desenvolvimiento gerencial del personal referido, ya que no conocen en su totalidad esta característica fundamental para el desarrollo de la PNL en todos los ámbitos. Por ello se propone, el uso de la PNL, para que posibilite el desarrollo de habilidades con las que se puedan concebir resultados que optimicen la comunicación del personal directivo de los colegios referidos en los actuales tiempos de pandemia.
La crítica al marxismo en el pensamiento de Carlos Rangel
Authors: Favio Osorio Leonardo
Published: September 2021

Carlos Rangel fue un intelectual que hizo agudas críticas a las sociedades latinoamericanas y del tercer mundo en general, entre otras razones, por no asumir la responsabilidad en su falta de prosperidad y en su lugar atribuir a factores externos como el imperialismo americano la causa de su pobreza. Eso dio lugar a que aceptaran ideologías como el marxismo, con un plan preconcebido de redención social para los pueblos oprimidos. En ese sentido, el objetivo de este artículo es analizar el texto de Carlos Rangel (1988) “Marx y los socialismos reales”, en el cual se hace una crítica a lo que ha sido el marxismo -socialista. Este texto viene a complementar lo que fueron sus obras anteriores: Del Buen Salvaje al Buen revolucionario (2006), y el tercermundismo (1982). Fue empleada la hermenéutica que implica un proceso de reflexión textual y contextual a partir del análisis del texto de Rangel para extraer sus conclusiones y aportes principales. Asimismo, la heurística sirvió para la comprensión de su obra. Se concluye, que Rangel asume el marxismo como una teoría con innumerables fallas teóricas y con resultados eminentemente negativos en los países donde se ha aplicado, pero que ha logrado sobrevivir a su fracaso producto de su buena propaganda política en un contexto donde se han rechazado las ideas capitalistas.
Rendimiento académico de estudiantes en Educación Superior: predicciones de factores influyentes a partir de árboles de decisión
Authors: Díaz-Landa Brenda , Meleán-Romero Rosana , Marín-Rodriguez William
Published: September 2021

El artículo tuvo como objetivo predecir el rendimiento académico de estudiantes de maestrías en educación, teniendo como autores principales a Camborda Zamudio (2014), Candia Oviedo (2019), Castrillón et al. (2020), Hussain et al. (2018), Yarlequé Wong (2019). Se empleó la técnica de árbol de decisión y minería de datos y herramientas que provee la inteligencia artificial para construir un modelo con el algoritmo J48 del software WEKA, teniendo en cuenta factores educacionales, familiares, socioeconómicos, de hábitos y costumbres. La muestra estuvo constituida por 237 estudiantes de una universidad pública en Perú, obteniendo mediante el coeficiente Kappa de Cohen un nivel de acierto del 66%. Los resultados dan cuenta de una metodología capaz de entrenar un sistema para clasificar a un estudiante, a partir de una de las categorías del rendimiento académico. Esta clasificación puede identificar a priori a los estudiantes con posibles problemas de rendimiento académico. Como resultado de ello, las medidas de acompañamiento y mitigación se pueden implementar de inmediato.
Driving and restraining forces of female Latin American entrepreneurship
Authors: Flores-Novelo Anel , Bojórquez Carrillo Ana Laura , Cuadrado Barreto Gabriela Carla
Published: September 2021

Women in Latin America present unique challenges and opportunities due to the family responsibilities they assume because of their gender role. The article focuses on examining the driving forces for Latin American entrepreneurship as empowerment and family support, and the restraining forces as their exclusion from males spheres, labor discrimination, lack of support, and families responsibilities from an intersectionality approach. The study includes the implications of how the entrepreneurial phenomenon develops in the context of women in Latin American. Studies of this type in this context being scarce. Likewise, an analysis of entrepreneurial femininity is carried out to identify the most appropriate Latin context. Equally, an analysis model is proposed that integrates these driving and restrictive forces. The methodology is qualitative, cross-sectional, integrates the case study, semi-structured in-depth interviews, and discourse interpretation. The conclusion presents the women barriers face in startup businesses and how their family responsibilities limit them, being the key support for their development, especially in Latin American when they face a macho atmosphere and a social representation associated with femininity (seems to be contrary to entrepreneurial spirit), the main role of women in the home, without economic support, with financial responsibility for taking care of their families, is shown as a cause for businesses not to grow.
The Nature, Prospect and Challenges of e-commerce:
Authors: Zaman Farhana , Tasnim Sadia
Published: September 2021

Recent studies have suggested that e-commerce has opened up a window of opportunities for the national economy of Bangladesh with minimum capital investment by digitalizing the information. Thereby, it is important to unravel the ontology of e-commerce for deepening the understanding of this digital revolution. To serve this purpose the study has conducted a small-scale survey on 29 females and 21 males, ranging in age from 16 to more than 55, who are all online shoppers both in the form of buyers and sellers. To supplement data to the survey, 10 in-depth interviews, five sellers and five buyers, are also taken. The study finds that e-commerce is gradually getting popular among the growing young generation of 24-34 age groups. Almost 100% of female shoppers prefer clothing, personal products to buy while male shoppers prefer electronic goods more. E-commerce creates a substitute marketing channel by terminating the manipulative role of middleman. Moreover, it serves as an empowering tool for women entrepreneurs. On the contrary, a few shoppers perceive e-commerce negatively for de-socializing people and creating false needs among young generation. In addition, a lot of virtual risks are explored associated with online business. Despite having these risks, e-commerce has made people’s life easier and thereby people should welcome the positive sides to underwrite the gradual development of e-commerce for keeping pace with this fast-moving world.
The study of primary DNA damage in the bone marrow of mice under the combined action of pesticides
Authors: Averianova Nataliya S. , Kara Liliya A. , Egorova Olga V. , Ilyushina Nataliya A.
Published: September 2021

Introduction. The study of the potential negative effects of combinations of several pesticide active ingredients is an important and understudied area of toxicological and hygienic research. The initial phase of the genotoxicant action on the genetic structures in cells is the primary DNA damage, the identification of which makes it possible to assess the early stages of the genotoxic effect of xenobiotics and their mixtures. The DNA comet assay is widely used for these purposes. The aim of the research is to assess the primary DNA damage under the combined action of pesticides. Materials and methods. To assess DNA damage the experiments on CD-1 mice of both sexes were performed using alkaline comet analysis. The concentration of active products reacting with thiobarbituric acid (TBA) in the blood serum of white outbred rats was assessed as a marker of lipid peroxidation. Results. It was found that mixtures of 2,4-D-acid + glyphosate and thiram + carbendazim did not cause the formation of breaks and alkali-labile sites in the DNA of mice bone marrow cells. Exposure to the combination of the technical grade active ingredients captan and fludioxonil induced the breaks and alkali-labile sites in the DNA of animal bone marrow cells. The comparison of the genotoxicity assessment results obtained by the comet assay and results of analysis of the TBA-active product concentrations in the rat blood serum suggests that the observed primary DNA damage upon exposure to the captan and fludioxonil combination can be mediated by the induction of lipid peroxidation and subsequent interaction of the resulting products with nucleic acids. Conclusion. The results indicate that some pesticides in combination can damage hereditary material in mammalian cells. Therefore, in order to ensure the safe use of pesticides for public health it is necessary to take into account the data on the genotoxicity not only of individual pesticide technical grade active ingredients but also their combinations.
Cytogenetic analysis in exfoliated buccal epithelial cells of the workers who come into contact with pesticides
Authors: Ilyushina Nataliya A. , Demidova Yulia V. , Makarova Mariya A. , Ilyushin Alexey Grigoryevich , Egorova Olga V. , Bereznyak Irina V. , Revazova Yulia A.
Published: September 2021

Introducton. Due to the increasing volumes of toxic substances entering the environment, including genotoxicants, it becomes necessary to conduct studies to assess their impact on people living in areas with high levels of pollutants, as well as people working in hazardous conditions. Epidemiological studies, in which damage to hereditary structures in human cells is assessed, in peripheral blood lymphocytes and buccal epithelial cells mainly, are carried out to determine the real genetic risk. Materials and methods. Samples of buccal epithelium were used. The study involved 69 people: 28 in the control group and 41 in the group of persons who were in contact with pesticides. The cytomorphological analysis took into account the following indicators: cytogenetic, cell proliferation, early and late destruction of nuclei. Results. The frequency of occurrence of the cells with micronuclei and protrusions in persons who were in contact with pesticides during their professional activities was increased 2.2 times, the frequency of cells with atypical nuclei - 2.5 times (differences in cytogenetic parameters between the groups were statistically insignificant). Statistically significant changes in the proliferation indicator were revealed - the frequency of cells with two nuclei (1.6 times), as well as the destruction indicators - karyorrhexis (4.5 times more often in nonsmokers and 8.2 times more often in smokers who work with pesticides) and karyolysis (the frequency of cells with initial karyolysis was increased by 3.4 times and 3.2 times with complete karyolysis). The index of accumulation of damage disorders was shown to be 4 times higher. Conclusion. The obtained data indicate an increased risk of damage to the genetic apparatus of cells in persons whose professional activities are associated with testing and using pesticides.
Analysis of banned or severely restricted chemicals and pesticides entering the Russian market under the Rotterdam Convention on the prior informed consent procedure for certain hazardous chemicals and pesticides in international trade
Authors: Khamidulina Khalidya Kh. , Tarasova Elena V. , Proskurina Angelina S. , Guseva Ekaterina A.
Published: September 2021

Introduction. In recent years, due to the stricter requirements for compliance with the provisions of the Rotterdam Convention, the volume of export notifications on the permission to import dangerous chemicals into the Russian Federation has increased significantly. Therefore, the purpose of our research was to analyze the nomenclature, volume, toxicity and danger of industrial chemicals and pesticides entering the Russian market, despite prohibitions or restrictions on their use at the international and national levels. Materials and methods. The materials used are applications for the import of chemical products (export notifications) of the National Designated authorities of the European Union, China, Great Britain, Serbia to the Russian Register of Potentially Dangerous Chemical and Biological Substances-a branch of the Federal State Scientific Research Center named after F.F. Erisman - in the period from 2018 to 2020. The year 2019 was considered in the most detail. Results and discussion. The analysis of applications showed an ever-increasing number of chemical supplies; for example, 130 notifications were received in 2018, 539 in 2019, and 565 in 2020. In 2019, the number of tin compounds prevailed in the nomenclature of imported products to the territory of the Russian Federation. As for the substances from Annex III of the Rotterdam Convention, most of the imported chemicals by tonnage were substances included in this document - 1,2-dibromoethane (EDB), carbofuran, ethylene oxide, ethylene dichloride (1,2-dichloroethane), which are imported for industrial use, and not for use as pesticides, as they are declared in the convention. Chemicals and pesticides imported into the country under the PIC procedure, with the exception of numerous derivatives of dibutyl - and dioctyltin, creosote, have an established hygienic standard in at least one human habitat. In most cases, they are assigned to hazard classes 1 and 2 according to the maximum permissible concentration. Conclusion. Chemical products that are highly dangerous for human health and the environment, which are banned or severely restricted in many states, caused specific and long-term effects on the body, and having high toxicity to natural biota are used in the Russian Federation economy. In this regard, there is a need to develop regulatory decisions at the national level and within the framework of the Eurasian Economic Commission on the prohibition or restriction of the circulation of substances and pesticides characterized by an unacceptable risk of exposure.
On the issue of analytical control of quinone derivatives in habitats
Authors: Grechina Marina S. , Suslova Alena V. , Belitskaya Viktoriya V.
Published: September 2021

Introduction. In the direction of normative and methodological assurance of the safety of environmental objects and imported food products, analytical approaches to the determination of a fungicide of the quinone class - dithianone in the air and citrus fruits were optimized. Materials and methods. Measurements were performed by tandem liquid mass spectrometry with a triple quadrupole mass detector (HPLC-MS/MS) in multiple reaction monitoring (MRM) mode using electrostatic spray as the ionization source. The substance from the air was concentrated on Tenax TA sorption tubes based on a porous polymer sorbent, followed by extraction of dithianone from the tubes with acetone. The preparation of samples of citrus fruits was carried out by extraction of acidified acetonitrile (selected optimal pH 2) in the presence of salts of magnesium sulfate, sodium chloride and sodium citrate two- and three-substituted, followed by centrifugation and filtration of the extract through disposable syringe membrane filters (QuEChERS technology). Results. The developed techniques were tested on real samples using the pesticide in agricultural practice. The revealed levels of dithianon do not exceed the lower limit of quantitative determination: 0.000071 mg/m3 in ambient air (with an RISL value of 0.0001 mg/m3) and 0.01 mg/kg in citrus fruits (with an established MRL value of 3 mg/kg). Conclusion. The developed methods are approved as official documents and supplement the base of analytical methods in terms of control of atmospheric air and imported food products.
On the issue of nongenotoxic cancerogenes
Authors: Revazova Yulia A. , Ilyushina Nataliya A.
Published: September 2021

Introduction. Chemical, physical or biological factors that can cause the formation and expansion of cancer cells are diverse in terms of both activity and mechanisms of action, which leads to the complexity of assessing the risk of developing malignant neoplasms. The aim. Discussion of the classification of carcinogens based on their ability to interact with DNA cell and possible mechanisms of genetic control of carcinogenesis processes induced by non-genotoxic carcinogens. Core content. The article draws attention to some controversial points related to the attribution of factors acting on the body to genotoxic or non-genotoxic carcinogens. The terminology used in the literature to describe genotoxic (mutagenic) and carcinogenic factors is presented. The mechanisms of action of non-genotoxic carcinogens are discussed. The important role of experts determining the danger to public health of factors with potential genotoxicity and carcinogenicity is noted. Conclusion. Non-genotoxic carcinogens are capable of inducing malignant growth through mechanisms not associated with direct damage to genetic structures in the cell. However, the realization of carcinogenic effects caused by such factors is determined by various mechanisms of genetic control.
Matemática Dinâmica e Raciocínio Hipotético-dedutivo: estudo envolvendo quadriláteros com o Geogebra
Authors: Molon Jaqueline , Siqueira Claudiomir Feustler Rodrigues de , Franco Sérgio Roberto Kieling , Basso Marcus Vinicius de Azevedo
Published: September 2021

Este artigo analisa a integração de Tecnologias Digitais de Comunicação e Informação (TDICs) na formação docente, em especial, a contribuição de um ambiente de Geometria Dinâmica (GD) no ensino, aprendizagem e avaliação de uma proposta pedagógica sobre quadriláteros e suas propriedades. A intervenção foi realizada com 18 participantes, licenciandos em matemática, em duas etapas, a primeira sem o auxílio de recurso tecnológico digital e a segunda com a construção geométrica dinâmica. Através desse estudo exploratório, discute-se como o pensamento geométrico pode ser favorecido pelo dinamismo das construções através da manipulação, da observação de invariantes, da elaboração de conjecturas, da argumentação lógico-matemática e prova matemática. Os resultados indicam que atividades voltadas ao pensar sobre conceitos geométricos num cenário de GD contribuem para o uso do raciocínio hipotético-dedutivo e o desenvolvimento de habilidades matemáticas, auxiliando a superar obstáculos tanto de natureza empírica quanto conceitual.
Cyberformação, produtos cinematográficos e produção de aulas de matemática
Authors: Souza Marília Franceschinelli de , Rosa Maurício
Published: September 2021

Esse artigo tem como objetivo analisar a experiência vivida por uma professora em um curso de Cyberformação com professoras/professores/professories de matemática, o qual buscava discutir e refletir sobre a responsabilidade social frente às macro/micro exclusões/inclusões na educação matemática por meio de Tecnologias Digitais (produtos cinematográficos, softwares, aplicativos). Para isso, o foco é dado nas produções realizadas por ela durante o curso, para compreendermos o movimento formativo vivenciado. Assim, consideramos que o curso de Cyberformação possibilitou repensar o ensino de matemática, encorajando-a a inserir discussões sociais e políticas em suas práticas. A experiência coloca luz à urgência de repensarmos o ser e o formar professoras/professores/professories de matemática, de forma a contribuir para uma formação docente crítica, cidadã e voltada à responsabilidade social.
Conceptions des enseignants du fondamental I dans le traitement des Situations-problèmes de proportionnalité
Authors: Alpha Ousmane , Almouloud Saddo Ag
Published: September 2021

RÉSUMÉ

Le présent article est tiré de nos travaux de thèse portant sur l’écologie et la proportionnalité dans l’enseignement fondamental au Mali de 1960 à nos jours. Notre problématique est centrée d’une part sur la persistance de la technique de la règle de trois malgré les différentes évolutions du curriculum prescrit de 1960 à nos jours au Mali et d’autre part sur les conceptions que les enseignants entretiennent avec la notion. À travers l’analyse des productions des enseignants soumis à un questionnaire, nous constatons que la règle de trois reste le modèle dominant dans le traitement de la proportionnalité et que les conceptions des enseignants influent beaucoup sur les comportements des élèves face à un problème de proportionnalité. En effet de 1960 à nos jours, nos résultats révèlent que la règle de trois a joué un rôle prépondérant dans le traitement des problèmes de proportions et de proportionnalité. Notre étude a révélé que cette restriction de la vie de la proportionnalité au détriment des règles qui rattachent les situations de proportionnalité au concept de référence la fonction linéaire est en grande partie liée à la conception que les enseignants de terrain (aussi acteurs de la noosphère) se font de la proportionnalité.
APPLICABILITY OF THE THESAURUS APPROACH TO MODELLING THE LEXICALSEMANTIC STRUCTURE OF A TERMINOLOGICAL FIELD
Authors:   Samara State Technical University, Zhuravlev A.P.
Published: September 2021

This article is the first part of the research focused on the applicability of the thesaurus approach as one of the instruments for building a lexical-semantic model of terminological fields belonging to various subject areas. Among other issues the article points out that the way of researching linguistic facts has changed from their analysis and description to modelling. After reviewing a number of scientific works by various linguists, the author proves the applicability of the thesaurus approach to a corpus of scientific lexis for its proper description, particularly for revealing the most characteristic types of semantic relations for every given terminological field. The applicability of the thesaurus approach is also proved in terms of the current stage of IT development. From this prospective, the potential of the thesaurus approach is determined in terms of analysis and structuring large amounts of text information for further automatic processing. With all this being said, the author, however, draws the conclusion that the complete formalization of a natural language lexis is essentially impossible.
LETTER RIDDLES AND LEGENDS ABOUT ALPHABET
Authors:   GITR Film & Television School, Pimonov V.I.
Published: September 2021

Object of the article: letter riddles based on splitting a word into parts by progressive removal of letters from it. Subject of the article: the structure of letter riddles. Purpose of research: to compare the structure of letter riddles with legends about the origin of alphabet. Research methods: structural and semantic. Results: the author argues that there is a structural similarity between letter riddles and legends about the origin of letters from parts of the dismembered human body. Field of application: literary and cultural studies. Conclusion: letter riddles based on breaking down the words into parts by progressive eliminations of the initial letter of each resultant word convey the motif of bodily fragmentation (“dismembered body”), which goes back to a sacrificial ritual. The author is indebted to Svetlana Gracheva, Dan Whitman and Oleg Zaslavsky for stimulating discussion and helpful advise.
System Diagnostics of Supporting-Rod Porcelain Insulation at Digital Substations
Authors: Tynchenko V. S. , Lukovenko A. S. , Kukartsev V. V. , Antamoshkin O. A. , Tynchenko S. V. , Sergienko R. B. , Mikhalev A. S. , Panfilov I. A.
Published: September 2021

This article is dedicated to an important problem of increasing the reliability of supporting-rod porcelain insulation at electric power substations. Porcelain insulation is installed on open switchgears (OSGs) of substations as part of the main switching equipment. Obsolescence and physical wear results in the destruction of supporting-rod porcelain insulators (SRIs), which often leads to serious consequences: shutdown of substation bus systems, emergency shutdown of substation equipment, reduction of power plant loads, as well as they pose a threat to operational personnel during operational switching. When supporting-rod insulation is replaced in due time, it significantly increases the reliability of the main substation equipment. Possible causes of failures were analysed using a graphical technique (Ishikawa diagrams). It has been established that sudden temperature changes of the ambient air are an important negative aspect, especially the transition of temperature values through 0ºC. The work represents a mathematical model of the development of microfractures in the insulation body of a ceramic insulator. The influence of external forces on the insulator leads to the appearance of additional stresses in it, to the destruction of new particles and to the sudden growth of microfractures. The article gives main SRI diagnostic techniques currently used in the electric power industry. According to statistics, it has been established that a relevant approach is the transition to digital technologies, which provides an automated information processing process without deactivating a piece of equipment. The article describes and proves that the proposed system of diagnostics of supporting-rod porcelain insulation at digital substations without deactivating a piece of equipment is a relevant area of scientific development. Within the framework of this scientific study, a patent for invention No. 2743887 dated 20 April 2020 was obtained.
The EVAL framework: Developing impact evaluation scholars
Authors: Strong Robert , Dooley Kim , Murphrey Theresa , Strong Jen , Elbert Chanda , Baker Matt
Published: September 2021

The complexities of food, agriculture, natural resources, and human sciences (FANH) programs and   projects require faculty to write and secure funding in addition to mastering skills such as evaluation competencies that integrate abilities in quantitative and qualitative research methods and evaluation theory and practice. The EVAL Framework was developed to advance skill development among FANH graduates to include these competencies and increase the pipeline of students who have the essential skills needed to advance FANH initiatives and priorities. The EVAL Framework includes four primary constructs: (a) Evaluation, (b) Value, (c) Active and Experiential Learning, and (d) Leadership. The purpose of EVAL is to build relationships with untapped FANH fields to develop a pipeline for graduates to become evaluation leaders for advancing food and agricultural sciences. This experiential learning and development model focuses on foundational and enrichment experiences, through formal coursework, project-based learning, and contextually rich environments. Mentoring, individualized development plans, scholarly learning communities, collaboration, transferable skills, and career planning and guidance activities are integrated into the EVAL framework to enhance skill development among EVAL scholars.
Profile of Snake Bite Deaths in South India: An Autopsy based Stud
Authors: Shanmugam K  , Gerard Pradeep Devnath S
Published: September 2021

Background: The burden due to the morbidity and mortality of snake bite in India is significantly higher. Itis estimated around 1.2 million snakebite deaths (average 58,000/year) has occurred in India from the year2000 to 2019. However the real burden of snake bite is unknown due to under reporting. This study aims tobring out region specific data on fatal snake bitesResults: The study was conducted at the dep of forensic medicine from 2016 to 2020. A total of 75 cases offatal snake bite cases were autopsied. The number of female cases 39 (52.3) and males were 36 (48.0). Themaximum no 52 (69.4%) cases were reported between the months of April to September. The common timefor snake bite was in the night 40 (53.3%) followed by the daytime 33 (44.0%). The place of incidence wheremost of the bites happened was in and around the homes of the victims 46 (61.3) followed by the workplaces29 (38.7%). The commonest site were the bite mark was noted in the lower limbs 33 (44%) cases. Around 22(23.9%) cases were seen in age groups of 45 to 59 years and 19 (25.3%) cases in 35 to 44 years. The speciesof snake in majority of the cases i.e., 65 (86.7%) was unknown. Around 40 (53.3%) cases of kidney samplesshowed acute tubular followed by congestion.Conclusion: The number of fatal bites were comparatively higher than that of the statistics available. Most ofthe findings of our study was consistent with the similar studies. The species of snake was largely unknownin this study because new snake species like hump nose pit viper can inflict fatal bites and are difficult toidentify. Region specific data on snake bite will reflect the exact volume of snake bites in the country andwould largely help in drafting policies to reduce mortality
Retrospective Study of Profile of Medico-legal Cases at Basaveshwara Medical College, Chitradurga
Authors: Shreedhar N.C  , Chandan.V  , Shreekrishna H K
Published: September 2021

Casualty department of any hospital is an important area, because most of the medical emergencies andalmost all medico legal cases report first to causality of hospital. The prime duty of doctor is to treat andsave the life of patient, however once stabilizedthe same doctor has to carry out exhaustive documentationof medico legal cases. This puts on extra burden on duty Doctor. The present study is carried out with a viewto understand the pattern and magnitude of Medico legal cases in this region. Two years retrospective datawas collectedbetween 1st January 2018 to 31st December 2019 from the casualty, Basaveshwara MedicalCollege, Chitradurga. Study revealed that Poisoning (40.04%) constituted majority of medico legal casesfollowed by road traffic accidents (31.12%) with male preponderance (3.32:1); majority of victims werebetween 21-30 years (32.5%); large number of victims were urban inhabitants (57.4%); most of the caseswere from Hindu community (90.4%); majority of cases (58.9%) reported to casualty within 1 hour fromthe time of incidence;maximum number of cases (40.50%) were reported between 6 pm - 12 am of the day;maximum number of cases was treated on the IPD basis (64.30%);more number of MLC was reported inmonth of August (48 cases).