bluuebunny/crossref_metadata_2025 huggingface dataset:
Vjerska problematika u pravaškom tjedniku Hervatska 1871. godine
Authors: Turkalj Jasna
Published: December 2023

U radu se na osnovi literature i periodike, prvenstveno priloga u pravaškom tjedniku Hervatska, daje pregled shvaćanja Ante Starčevića, Eugena Kvaternika, mladih suradnika u uredništvu i dopisnika pravaškoga lista o raznim pitanjima vezanim uz crkvenu i vjersku problematiku. U Hervatskoj će se pod utjecajem zbivanja na unutrašnjopolitičkoj sceni i u Europi tematizirati ukidanje Papinske Države i papina svjetovna vlast, izbor biskupa u Hrvatskoj, a osuda biskupa Strossmayera zbog njegovih istupa na Prvom vatikanskom koncilu bit će začetak žestokoga sukoba koji će se sljedećih mjeseci, a napose u vrijeme izbora za Hrvatski sabor i nakon njih, rasplamsati između pravaša i katoličkoga svećenstva koje je slijedilo strossmayerovsku Narodnu stranku. Prva opća hrvatska učiteljska skupština otvorila je u pravaškom tjedniku pitanje kontrole i nadzora Crkve nad javnim školama, dok je Pariška komuna iznijela na vidjelo različita shvaćanja o ulozi vjere u društvu, napose između Kvaternika i mladih suradnika Hervatske.
Relationship between subjectively-rated and objectively-tested physical function across six different medical diagnoses
Authors: Benz Thomas , Lehmann Susanne , Sandor Peter S. , Angst Felix
Published: December 2023

Objective: To quantify and compare associations and relationships between self-rated and tested assessments of mainly mobility-related physical function in different diagnoses.
Design: Six longitudinal cohort studies before and after inpatient rehabilitation.
Patients: Patients with whiplash-associated disorder (n = 71), low back pain (n = 121), fibromyalgia (n = 84), lipoedema (n = 27), lymphoedema (n = 78), and post-acute coronary syndrome (n = 64).
Methods: Physical function was measured with the self-rated Short-Form 36 Physical functioning (SF-36 PF) and with the tested 6-Min Walk Distance (6MWD) and assessed by correlation coefficients. Across the 6 cohorts, the relationship between the 2 scores was compared using the ratio between them.
Results: The correlations between the 2 scores were mostly moderate to strong at baseline (up to r = 0.791), and weak to moderate for the changes to follow-up (up to r = 0.408). The ratios SF-36 PF to 6MWD were 1.143–1.590 at baseline and 0.930–3.310 for the changes, and depended on pain and mental health.
Conclusion: Moderate to strong cross-sectional and moderate to weak longitudinal correlations were found between the 6MWD and the SF-36 PF. Pain and mental health should be considered when interpreting physical function. For a comprehensive assessment in clinical practice and research, the combination of self-rated and tested physical function measures is recommended.
Energy Alterations in Patients with Benign Prostatic Hyperplasia and How can we Treat this Condition without Using Surgery?
Authors: WL Huang
Published: December 2023

Introduction: Benign prostatic hyperplasia is an obstructive of urine flow very common in elderly patients. The Purpose of this study is to demonstrate that patients with benign prostatic hyperplasia have energy deficiency inside the five internal massive organs and the treatment of this condition is of paramount importance to treat the cause of the formation of this problem and not just treating the symptoms, that it is the problem in the prostate itself. Methods: through three case reports. All of them have prostatic hyperplasia diagnosis according to Western medicine doctors but they were not improving their symptoms using the medications prescribed by them. They went to my clinic to treat another condition but told me that they also were having urinating problems mainly in the morning. I measured the energy of the five internal massive organs (Liver, Heart, Spleen, Lungs, and Kidney) using a crystal pendulum. Results: All internal massive organs of the three patients were in the lowest level of energy, rated one out of eight. The treatment of this condition changing dietary habits according to Chinese dietary counseling, auricular acupuncture with apex ear bloodletting and systemic acupuncture, and replenishing the internal organs’ energy using highly diluted medications according to the theory of Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine and using crystal-based medications was of paramount importance to treat the cause of benign prostatic hyperplasia and not just treating the symptoms. The Conclusion of this study was to demonstrate that patients with benign prostatic hyperplasia have energy deficiency inside the five internal massive organs of the five elements theory of Traditional Chinese Medicine. The treatment of this condition rebalancing the internal energy using Chinese dietary counseling, auricular acupuncture with apex ear bloodletting, and systemic acupuncture and replenishing the internal massive organs energy using highly diluted medications according to the theory of Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine and crystal-based medications is very important to treat the cause of hyperplasia prostatic benign in the energy level, invisible by the naked eyes.
Primary Reconstruction of Bladder Neck Transection and Vaginal Laceration Post Blunt Abdominal Injury a Case Report
Authors: A Khalid
Published: December 2023

Blunt abdominal injury is not uncommon in the paediatric population. The presentation can be immediate or delayed, and if not promptly recognized may be attended with complications such as septicaemia, shock or death. Simple, readily available and cheap imaging techniques such as abdominal radiograph and ultrasound scan still remain relevant in the diagnosis of blunt abdominal injuries where abdominal computerized tomography is unavailable or unaffordable. This can expedite the decision for an early surgical exploration. In girls, complete bladder neck transection with vaginal wall injury is a rarely reported and unusual association of blunt abdominal injury more so with delayed presentation in the absence of an associated pelvic fracture. This rare trauma entity in a child can pose a diagnostic difficulty leading to delayed presentation. This is a case of 3 year old girl with 3 weeks history of trauma to the abdomen from collapsed building fence during a heavy downpour. She later developed progressive abdominal distension with pain, constipation, vomiting, fever and drainage of clear fluid per vaginam. She had visited several hospitals but was managed non-operatively. Over the period the patient had some relief of symptoms until she presented to our facility with poorly defined features of peritonitis following a referral from a peripheral hospital. Abdominal ultrasound scan revealed intraperitoneal fluid collection. She was resuscitated and had exploratory laparotomy with primary reconstruction of the bladder neck transection and vaginal wall laceration. She did well immediate postoperative except for the superficial surgical site infection and during follow-up visits. Primary repair of traumatic bladder neck transection and vaginal wall laceration in paediatric patients with delayed presentation of blunt abdominal injury is a feasible option of management. However, long term follow up is recommended as secondary procedures may become necessary.
Pattern and Clinical Characteristics of Cystic Kidney Disease Patients in a Tertiary Centre, South-West Nigeria: A Retrospective Study
Authors: S Dada
Published: December 2023

Background: Cystic kidney disease is a group of disorders that are characterized by the formation of cysts in the kidneys.It is a major cause of end-stage renal disease (ESRD) worldwide. Objectives: This study aimed to determine the pattern and clinical characteristics of patients with cystic kidney disease who presented at a tertiary hospital in South-West Nigeria. Methods and Materials: We reviewed the records of patients admitted with cystic kidney disease over an 8-year period at Ekiti State University Teaching Hospital. Data extracted included patients’ demographics, clinical presentations, and treatment outcomes. We compared the data between patients with ADPKD and other types of kidney cysts and summarised the treatment outcomes among the patients. Result: The prevalence of cystic kidney disease was 9.2% and the mean age of the patients was 52.87 years with a male predominance. The most common type of kidney cyst was simple renal cysts (53.2%), followed by ADPKD (40.4%). Incidental findings with no symptoms were the most common mode of presentation (61.7%), followed by abdominal pain (38.3%) and palpable abdominal swelling (36.2%). Nephrolithiasis was documented in 4.3% while the frequency of hypertension, haematuria and urinary tract infection was 55.3%, 14.9% and 8.5 %respectively. More than one in five ADPKD patients (21.1%) developed end-stage renal disease. Overall, the majority 41(87.2%) were managed conservatively. Conclusion: This study contributes valuable insights into the pattern and clinical features of cystic kidney disease in SouthWest Nigeria, further enriching the existing data on this condition within the region.
Genetic Variability and Association Analysis for Yield and its Components in Alkaline and Inland Saline Stress in Rice (Oryza sativa L.)
Authors: Kandibanda Sai Kylash , Gaddam Shiva Prasad , Satturu Vanisri , Saida Naik D
Published: December 2023

The experiment was conducted at Agricultural Research Station, Kampasagar, Nalgonda, Telangana, India during the rabi season (December, 2020 to May, 2021) to identify suitable lines tolerant to alkalinity and inland salinity stress in rice. Analysis of variance evinced plenteous quantum of variability in all the 36 genotypes investigated. Phenotypic coefficients of variation were higher than genotypic coefficients demonstrating the effect of the prevalent stress environment. High estimates of genotypic coefficient of variation, phenotypic coefficient of variation, heritability, and genetic advance as percent mean was observed for the traits, seedling mortality, number of filled grains panicle-1 and sterility %. These findings suggested the preponderance of additive gene action for these characters. The remaining traits were mostly under the influence of non-additive gene effects as they recorded low to moderate estimates of genetic advance.  Studies from association analysis showed that number of productive tillers hill-1 and number of filled grains panicle-1 had a positive significant correlation with yield whereas, seedling mortality and sterility % had a negative significant association with yield. Path analysis revealed that traits number of productive tillers hill-1, number of grains panicle-1 and 1000 grain weight had a positive direct effect on yield.  Hence primacy should be given to the above-mentioned traits to develop alkalinity and inland saline tolerant and high yielding rice cultivars. Lines CT 118911, Sahel 177, M 202 and KPS 10654 were found to be promising entries and can be used tolerant parents in the breeding programme. Three principal components combined could explain 68.86% of the total variation.
WAYS OF RATIONAL USE OF WATER RESOURCES IN THE CONDITIONS OF POST-WAR RECLAMATION SYSTEMS IN THE SOUTH OF UKRAINE
Authors:   Kyiv National University of Construction and Architecture, Marshall Daniil , Zhukova Olena ,   Kyiv National University of Construction and Architecture
Published: December 2023

After the explosion of the Kakhovka hydroelectric power station, the problem of restoring damaged areas of reclamation systems and rational use of water resources in the de-occupied territories of southern Ukraine is extremely relevant today. An integral part of solving this problem is the theoretical justification and assessment of filtration losses in damaged areas of open drainage channels with interception of this flow by drainage structures. This study presents a methodology for calculating the filtration losses of water from a main canal that runs in an excavation with a channelside pipe drainage. The calculations take into account the pressure drop on the canal lining. The filtration water losses per linear metre of the main channel of the Ingulets irrigation system were determined, taking into account the filtration resistance of the screen, which is economically feasible to restore from local water-resistant natural materials. In this case, the channel drainage performs two functions. Firstly, it prevents flooding of the territory; secondly, it is possible to use innovative technologies to return part of the filtration effluent for use in various water supply sectors of the region. The research results will allow us to further develop recommendations for effective engineering protection of water resources from pollution and depletion in this region.
VALORIZATION OF PHOSPHOGYPSUM IN UKRAINE BY CREATING COMPOSITE MATERIALS FOR STRUCTURAL LAYERS OF ROAD PAVEMENT
Authors:   Lviv Polytechnic National University, Novytskyi Yurii , Topylko Nataliia ,   Lviv Polytechnic National University, Rainchuk Nataliia ,   Lviv Polytechnic National University
Published: December 2023

Ukraine's transition to an energy-efficient economy as part of its overall transformation to EU standards is a difficult but crucial challenge. The country's post-war recovery will involve modernizing the entire infrastructure in line with EU sustainable development standards. In particular, the road sector, being the most resource-intensive in construction, must be in line with the goals of the European Green Deal, namely: reducing greenhouse gas emissions resulting from the extraction and processing of natural resources, implementing the principles of the circular economy, achieving economic growth by maximizing the substitution of natural materials for man-made waste, minimizing negative environmental impact and using advanced green technologies (Natsionalna ekonomichna stratehiia, 2021). Promoting the principles of the circular economy and implementing the best European practices in the reuse of industrial waste is not only a requirement for Ukraine's successful accession to the EU, but also a prerequisite for the effective implementation of infrastructure projects, especially during the post-war reconstruction of the country. However, such ambitious goals can be a huge challenge for our country, particularly in environmental recycling projects in construction, where the most important issue is to eliminate the simplest and most attractive solution of using natural materials rather than replacing them with industrial waste. The article contains research materials on solving the problem of utilization of phosphogypsum waste by using it in the structural layers of road pavements. For this purpose, composite mixtures based on raw dump phosphogypsum (SE "Sіrka", Novyi Rozdil) were prepared. Laboratory tests have established that composite materials based on phosphogypsum meet the requirements of the State Standard of Ukraine for structural layers of road pavement.
DRYING OF CENOSPHERES RECOVERED BY THE WET-BASED METHOD FROM COAL FLY ASH FOR THEIR RATIONAL USE
Authors:   Lviv Polytechnic National University, Kindzera Diana , Atamanyuk Volodymyr ,   Lviv Polytechnic National University, Hosovskyi Roman ,   Lviv Polytechnic National University, Mitin Ihor ,   Lviv Polytechnic National University
Published: December 2023

Since slag and coal fly ash (CFA) are major global pollutants produced by thermal power plants (TPPs), special attention should be paid to their rational disposal. Scanning electron microscopy (SEM) was used to study the morphology of CFA and it was suggested that the use potential of CFA is high due to the presence of a large number of cenospheres (CSs), that can be recovered mostly by wet methods for the production of the wide range of products with improved properties. However, such decisions regarding the application of the cenospheres are largely related to the problem of their drying after removal. The article is devoted to the investigation of the filtration method as less energy-consuming for the drying of cenospheres. The effect of the drying agent velocity on the mass transfer intensity has been established. The values of mass transfer coefficients have been calculated based on the thin-layer experimental data and equation . Calculated mass transfer coefficients for cenospheres have been correlated by the dimensionless expression , based on which equation has been proposed to calculate the mass transfer coefficients, which is important at the filtration drying equipment design stage.
Uso de Ellansé® (Policaprolactona) em terço médio e inferior da face - relato de caso
Authors: Pinola Vitória Otero , Oliani Sílvia Aparecida Gimenes Cantele , Feitosa Pedro Carvalho , de Biasi Daniela Borges , Miyahira Alexandre
Published: December 2023

Nos últimos anos, diante do crescente cenário de busca pelo rejuvenescimento facial funcional e cosméti co, o uso de biomateriais percutâneos indutores de colágeno fez-se relevante, sendo uma importante ferramenta biotecnoló gica de reparo e prevenção do envelhecimento. O envelhecimento leva a perda de volume em todas as camadas da estrutura anatômica da face devido à remodelação óssea e consequente caimento dos coxins superfi ciais de gordura. Esse processo se inicia no fi nal da segunda década e início de terceira década de vida e está associada ao aparecimento de vários sinais de envelhecimento. O uso de preenchedores pode corrigir os sinais do envelhecimento por restaurar volume às camadas de tecido mole e a nível supra periostal. O bioesti mulador a base de Policaprolactona é um preenchedor composto por microesferas de Policaprolactona (30%) suspensos em um veículo de carboximeti lcelulose (70%). O Ellansé® é considerado o padrão ouro, ati vando os fi broblastos para que produzam colágeno ti po I, deixando a pele mais fi rme, melhorando a textura e o brilho e deixando o seu contorno mais defi nido devido ao seu efeito preenchedor. Neste trabalho é apresentado um relato de caso que fez uso do Ellansé® em uma paciente de 53 anos, onde se espera que haja uma reposição do volume perdido pela idade e melhora da qualidade dérmica.
BIOSKOP DAN MASYARAKAT KOTA PALU, 1950-1998
Authors: Aditama Muhammad Reza
Published: December 2023

This article aims to answer the following 3 questions: 1) How is the development of cinema in Palu City?; 2) How is the influence of cinema on the people of Palu City?; and 3) Why does the presence of cinema produce a new cultural identity in the people of Palu City? The problems in this article are solved using historical methodologies and anthropological approaches. The results of this study indicate that: 1) In the period between 1951-1990 the development of cinema was only in the form of an increase in number, then in 1991 there was one cinema that was different from previous cinemas so that it could create a discourse on traditional and modern cinema and the difference was the shape of the building, facilities, and film distribution network. However, without distinguishing between traditional and modern cinemas, all of them stopped operating at the end of 2000 because there were so many alternative media for film screenings; 2) Cinema as popular culture can increase and have an influence on the consumption of fashion, music, and especially films to the behavior of the people in Palu City; 3) Cinema, in the process of presenting a new cultural identity there are several phases in certain periods in society, namely initially only as popular culture (1951–1989), the second learning space (1984–1998), the third non-privacy space (1990–2000), then these three things become markers that cinema, which is only space, can form a new cultural identity in society.
PEREMPUAN DAN LALAMPA: PERKEMBANGAN KEHIDUPAN SOSIAL EKONOMI PENJUAL LALAMPA DI TOBOLI
Authors: Wahyudi Imam
Published: December 2023

The problems in this paper are (1) What are the reasons women in Toboli choose to become lalampa sellers? (2) How is the development of the lalampa culinary business in Toboli? (3) How is the socio-economic development of lalampa sellers in Toboli? This study uses a descriptive qualitative method with a historical approach. Data collection techniques used are literature studies and field studies consisting of observations, interviews, and documentation. This research was conducted in Toboli Village, North Parigi District, Parigi Moutong Regency. The results of this study found three conclusions, namely: First, there are five factors that cause women to become sellers of lalampa, which are driven by increasing economic needs, women's educational background, domestic roles inherent in women, the background of life raised in a merchant environment, and being motivated or having a desire to follow the previous successful lalampa sellers; Second, Toboli lalampa is a culinary commodity that has become an economic commodity for women in Toboli and has become the identity of Toboli itself; Third, the development of Toboli's lalampa culinary business has changed the roles, duties, and functions of women in the family. Now, the women selling lalampa in Toboli have become the economic support for their families and also they have contributed greatly to raising the socio-economic status of their families.
GERAKAN MADI DI SALENA
Authors: Nofian
Published: December 2023

This article attempts to answer the following 3 questions: 1) what is the background of the Madi Movement in Salena?; 2) How was the development process of the Madi Movement?; 3) How did the Madi Movement end? The research questions were solved using a historical methodology through a sociological and anthropological approach with analysis tools of Movement theory supported by several religious movement concepts. Source searches were carried out at government offices, regional libraries, Tadulako University libraries, and were completed with observations and interviews. The results of this study found three things, namely; First, the emergence of the movement in Salena as a form of social protest for remote communities as a result of social changes that occurred in Palu City. The second development of the movement in Salena was led by Madi as a shaman (sando) and also as a silat teacher (kantau) who founded a college called "Dente Sepuluh". Third, the peak of the movement in Salena stems from a clash between the police and Madi's group that killed three police officers. Madi's death and the detention of a number of his groups marked the end of the Salena Movement.
PENGGARAMAN TALISE DALAM LINTASAN SEJARAH PALU, 1840-2018
Authors: Jefrianto Jefrianto
Published: December 2023

Kawasan penggaraman yang terletak di wilayah Talise telah menjadi saksi perjalanan sejarah Palu. Penggaraman Talise diperkirakan telah ada sejak akhir abad 19, bertahan dalam kepungan perkembangan pariwisata pantai di Teluk Palu, bahkan bertahan setelah dilanda bencana gempa bumi dan tsunami 28 September 2018. Tulisan ini berangkat dari dua pertanyaan mendasar: Pertama, bagaimana peran kawasan penggaraman Talise dalam sejarah Palu? Kedua, bagaimana kawasan penggaraman Talise mampu bertahan hingga saat ini? Metode penelitian yang digunakan adalah metode sejarah, meliputi heuristik, kritik sumber, interpretasi, serta historiografi. Batas awal tulisan ini adalah tahun 1840 yang ditandai dengan kedatangan penduduk dari Cikoang ke Palu yang memperkenalkan pengetahuan pengolahan garam kepada masyarakat, sedangkan batasan akhir yakni 2018, menandai peristiwa bencana gempa bumi dan tsunami 28 September 2018 yang melanda Palu yang menyebabkan kerusakan di kawasan penggaraman Talise.

Kata Kunci: Penggaraman, Talise, Palu
"Soja = Glifosato + Paramilitares": Agro-extractivism and environmental violence in Paraguay
Authors: Ezquerro-Cañete Arturo
Published: December 2023

This article examines the different forms of structural, everyday, and symbolic violence brought about by the sweeping expansion of agribusiness in Paraguay over the past few decades. This discussion is framed around the protest slogan of the organized campesino movement: "Soja = Glifosato + Paramilitares" ["Soy = Glyphosate + Paramilitary"]. The banner encapsulates the twin forces of environmental violence and toxic dispossession faced by the peasant and Indigenous communities who live near soybean fields. On the one hand, the quotidian violence caused by agrochemical drifts – accumulation by fumigation – that leads to various forms of toxification, slow death and corporeal attrition that reduce populations through ill health, infertility, and furtive modes of displacement. On the other hand, the more open, direct, and deadly violence involving the assassination of peasant activists and local leaders along with the criminalization of social protests. The adamant and visceral dismissals by agribusiness elites of the grievances of campesinos represents another form of symbolic violence, highlighting the obstacles that rural communities and peasant social movements face in addressing toxic landscapes and environmental violence of the agro-extractivism. 
Normativity and Body: Efficient Control Mechanisms in Society and School
Authors: Santos Welson Barbosa , Martins Rone Rosa , Castejon Mariângela , Motta Maria Carolina Carvalho , De Souza Thomas Magno Barbosa
Published: December 2023

Objectives: The objective of this discussion is to establish a relationship between concepts and historicity of the body, sexuality and domination, from the perspective of Michel Foucault. This is because we understand the body as involved in existing power relations, from and in the various instances of society. In this sense, biopower presents itself as a control mechanism, once well instituted and established in society it is diluted in micro relationships.
 
Methodology: as part of the challenges of the Education in the Cerrado and Citizenship Research Group, a set of debates were carried out by members of the group. Using Discourse Analysis from a Foucauldian perspective as a tool, the search was to explain historical aspects specific to the constitution of subjects in different sociocultural positions, thus, we sought to make an ethical and aesthetic approach.
 
Results and conclusion: sexual discourse covered in disguise is no longer supported by mechanisms of oppression, but by mechanisms of ideology that cannot be escaped, as they are everywhere. In this way, we understand that the discourse on the modern repression of sex is sustained by micro relationships and no longer by oppression, an ideological bias passed from father to son, reinforced at school, endorsed by the teacher-student relationship.
 
Implications of the research: the research leaves questions: will schools being restricted from dealing with the dilemmas of sexuality and gender identities contribute to this move towards freedom of sexual language and the understanding of the real meaning of sex, if restricted to family cultural values? Would it be a return to the values ​​and customs of the traditional Brazilian family?
Sustainable Management for oat Grain Yield and Quality Based on Nitrogen Supply and Seeding Density
Authors: Da Rosa Juliana Aozane , Da Silva José Antonio Gonzalez , Alessi Odenis , Peter Cibele Luisa , Magano Deivid Araújo , Panozzo Luís Eduardo , Jung Márcia Sostmeyer , Zardin Natália Guiotto
Published: December 2023

Purpose:  The objective of this study is to evaluate a sustainable management for oat crops with high nitrogen use efficiency combined with high seeding density to improve grain yield and quality while increasing oat competitive ability against ryegrass.
 
Method/design/approach: The experiment was carried out in the years 2020, 2021 and 2022, with an experimental design of randomized blocks with four replications, in a 4 x 3 factorial arrangement, for sowing densities (100, 300, 600 and 900 viable seeds m-2) and form of nutrient supply: [single dose, (100%) at phenological stage V4 (fourth expanded leaf); fractional (70/30%) at the V4/V6 phenological stage (fourth and sixth expanded leaves) and; fractionated (70/30%) at phenological stage V4/R1 (beginning of anthesis)], respectively. Indicators of productivity and chemical quality of oat grains were analyzed, and lodging and ryegrass inflorescences exposed on oat plants were analyzed in the field.
 
Results and conclusion: The application of a single dose of nitrogen at the V4 stage resulted in higher grain and oat straw yields, without changes in the crude protein and crude fiber content of the grains. The combination of this nitrogen application method with a sowing density of 490 seeds m-2 increased the competitive capacity of white oat plants, reducing the number of ryegrass inflorescences.
 
Originality/value: This study contributes to more sustainable management practices in the use of nitrogen and the contribution of plant density in promoting competitive ability, reducing dependence on agrochemicals in ryegrass control and promoting food security and environmental protection.
Place of Allogeneic Hematopoietic Stem Cell Transplantation in the First Complete Remission in Ph-positive Acute Lymphoblastic Leukemia in Adults
Authors: Afanaseva K. S. , Smirnova A. G. , Vlasova Yu. Yu. , Moiseev I. S. , Bondarenko S. N.
Published: December 2023

Introduction. Ph-positive acute lymphoblastic leukemia (ALL) is a high risk group of B-lineage acute lymphoblastic leukemia (B-ALL). Since tyrosine kinase inhibitors (TKIs) were introduced, controversial data have been obtained on the efficacy of allogeneic hematopoietic stem cell (allo-HSCT) in the first complete remission.

The objective was to evaluate the efficacy of allo-HSCT in the first complete remission of Ph-positive ALL in adult patients after remission induction with continuous chemotherapeutic exposure in combination with TKIs.

Methods and materials. The retrospective analysis included 74 patients with a median age of 32 years (range 18–59) after allo-HSCT in the first complete remission and 58 patients with a median age of 39 years (range 18–65) in the first complete remission after conservative therapy. Ninety-one per cent and 83 % of patients received imatinib as TKIs in remission induction in the allo-HSCT and conservative therapy groups, respectively. The median time from the first complete remission to allo-HSCT was 7 months (range 2–33). Thirty-six patients (49 %) had positive minimal residual disease (MRD) status prior to allo-HSCT. Eighteen patients (14 %) over 40 years underwent allo-HSCT in the first complete remission.

Results. Allo-HSCT improves overall survival (OS) and relapse-free survival (RFS) and by 9 months since the achievement of the first complete remission, they were 70.1 (95 % CI 56.4–88.6) in the allo-HSCT group versus 45.1 (95 % CI 33.4–61.0) in the conservative group, p=0.025 and 63.3 % (95 % CI 47.6–84.1) in the allo-HSCT group versus 44.8 % (95 % CI 33.2–60.4) in the conservative therapy group, p=0.04, respectively. Allo-HSCT in patients over 40 years does not improve 5-year OS and RFS and were 57.2 % (95 % CI 30.0–84.4) versus 59.8 % (95 % CI 36.9– 82.7), p=0.69, and 42.6 % (95 % CI 14.0–71.2) vs. 50.9 % (95 % CI 29.5–72.3), p=0, 88, respectively.

Conclusion. Allo-HSCT performed before 9 months from achievement of the first complete remission after induction with imatinib is the preferred method of remission consolidation in patients from 18 to 40 years old. The optimal therapy for patients older than 40 years in the first complete remission is a conservative approach in combination with TKIs.
Pathomorphology of the heart in COVID-19
Authors: Rybakova M. G. , Kuznetsova I. A. , Azanchevskaya S. V. , Vysotsky V. E. , Vlasova M. T.
Published: December 2023

Cardiovascular system is a significant target for SARS-CoV-2.

The objective was to study morphological changes in the heart in patients who died from COVID-19.

Materials and methods. Autopsy material of the heart of those who died from COVID-19 (700 autopsies) was analyzed. The analysis of autopsy protocols was carried out, macroscopic changes were assessed, histological preparations stained with hematoxylin and eosin, van Gieson stain, Schiff’s reagent, the results of immunohistochemistry with antibodies to CD68, CD3, CD4, CD8, CD45 were analyzed.

Results. The leading pathomorphological changes in the heart in COVID-19 are acute discirculatory changes with predominant disorders in small intramyocardial vessels. Lymphocytic myocarditis was confirmed in 1 % of cases.

Conclusion. Damage to cardiomyocytes in COVID-19 is multifactorial and associated with manifestations of the underlying cardiovascular pathology, changes in intramyocardial vessels due to the action of SARS-CoV-2, and hypoxia due to progressive lung damage.
High Density Lipoproteins: Metabolism, Biological Functions and Risk of cardiovascular pathology
Authors: Smirnova N. N. , Kuprienko N. B. , Urazgildeeva S. A.
Published: December 2023

High levels of high-density lipoproteins (HDL) in blood plasma have traditionally been considered an anti-atherogenic factor, but this opinion is not always supported by epidemiological and genetic studies. The functions of lipoproteins are of much greater importance, the main of which is the implementation of the reverse cholesterol transport (RCT) from cells to the liver. The part 1 of the review presents the sequence of passage of cholesterol in HDL, shows the importance of each link in this chain for the development of atherosclerosis; the main methods for determining RCT are given. Changes in the structure and function of HDL, which play the important role in the pathogenesis of a number of chronic diseases that in one way or another stimulate the development of atherosclerosis, are considered in part 2 of the review.
Noninvasive method of monitoring the functional state of living cells
Authors: Parkhomenko T. V. , Galibin O. V. , Tomson V. V.
Published: December 2023

The article is devoted to the generalization of information on the use of potential-sensitive probes (PSP) to assess the viability and functional state of an entire cell. Usage of membrane PSP is of great importance for assessing both the viability and functional integrity of the cells and their structural components (mitochondria, nuclei, cytoplasmic membranes, ion channels). Potential advantage of this approach includes studies of native viable cells in order to assess functional state of donor hematopoietic cells before transplantation as well as upon their storage and cultivation. These staining tools allow to assess the state of cellular bioenergetics, i.e., the balance between production and consumption of energy in living cells. The production of energy in mitochondrial structures ensures the cell viability, whereas its impairment leads to the development of different disorders and aging. In clinical medicine, this method can be used to assess the condition of donor cells before their transplantation, primarily in oncohematology, the treatment of patients with severe ischemic myocardial lesions.

The purpose of the work: to study the results of the research of the use of PSP to assess the energy potential and viability of cells.
تحديات تطبيق التقويم الذاتي ومعايير الاعتماد المدرسي في المدارس الأهلية بمحافظة جدة والحلول المقترحة
Authors: السلمي سارة
Published: December 2023

هدف البحث الحالي إلى التعرف على تحديات تطبيق التقويم الذاتي ومعايير الاعتماد المدرسي في المدارس الأهلية بمحافظة جدة من خلال استخدام المنهج الوصفي للتعرف على هذه التحديات والحلول المقترحة، ولتحقيق أهداف الدراسة قامت الباحثة باستخدام المقابلة والاستبانة كأداة لجمع المعلومات، وتكون مجتمع الدراسة من عينة عشوائية من مديرات ووكيلات المدارس الأهلية للمدارس التي تشرف عليها الباحثة في محافظة جدة في الفصل الدراسي الأول للعام الدراسي (1445هـ) وقد بلغت عينة الدراسة (35) مديرة ووكيلة.
فاعلية البحث العلمي في الاستدامة للمنتج الملبسي والأزياء وأثرها في حماية البيئة
Authors: صدرالدين إيمان
Published: December 2023

إن التطور التكنولوجي، والعولمة، والتغير في السلوك الشرائي للمستهلك يؤدي إلى ظهور أسلوب انتاج أسمي بالموضة السريعة للأزياء، كما اعتمد هذا الأسلوب على سرعة نسخ كل ما تقدمة دور الأزياء العالمية الكبرى من تصميمات وتصنعها بأسرع وقت بأقل تكلفة وتوفر أحدث صيحات الموضة للمستملك بأعداد كبيرة وبأقل الأسعار؛ وهناك الكثير من الأثار السلبة عل البيئة والمجتمع والعمالة وحتى المستملك الذي أصبح يبتعد عن جودة السلعة بسب اقتناء الموضة الحديثة. بثمن رخيص وإن ذلك الأسلوب في الإنتاج مضاد للاستدامة والتي تعتمد في الأساس على الالتزام بأخلاقيات التصميم والإنتاج والحفاظ على البيئة وحقوق العمالة. يهدف البحث الحالي على التركيز على البحث العلمي في مجال الاستدامة وخاصة في مجال الأزياء والملبس لما لها اثار ضارة على البيئة بشكل كبير إلقاء الضوء على الأثار السلبية للموضة السريعة للأزياء. وتحدد أخلاقيات الاستدامة في مجال الازياء وإنتاجها. وابراز الممارسات الخاطئة التي تظهر من شركات الموضة السريعة. كما يجب اقتراحات لتطبيق قواعد والمعايير في الاستدامة في الموضة السريعة للأزياء. وتتحدد مشكلة البحث في التساؤل التالي ما مدى فاعلية البحث العلمي في الاستدامة في مجال الملابس؟ وما أثرها على البيئة؟ واتبعت الدراسة المنهج التحليلي لتحلل لتأثير الموضة السريعة للأزياء والملابس على البيئة، والمنهج التطبيقي بتقدم الأفكار والمقترحات التي تجعل من البيئة نظيفة للاستدامة وتطبيقها في مجال الملابس. واجراء مقابلات للخبراء ومتخذي القرار في مصانع وشركات الملابس الجاهزة لاستطلاع آرائهم من خلال مقياس لمعرفة هل الاستدامة في الملابس واستخدام خامات امانة لها تأثير على البيئة نحو الدراسة المقترحة والتوصل الى النتائج. وتوصلت نتائج الدراسة الى ووجود علاقة ذات دلاله إحصائية بين الاستدامة في مجال الملابس والمستهلك وبين الحفاظ على البيئة بنسبة 83% متوسط الارتباط. كما توجد علاقة ذات دلالة احصائية بين العاملين في تصنيع الملابس والمحافظة على معايير الاستدامة لحماية البيئة بين الاستدامة 73%. وتوصي الباحثة بالاهتمام بالبيئة واستخدام خامات صديقة لبيئة كما توصي بالعديد من الدراسات التي تهتم بمجالات الاستدامة للمحافظة على البيئة.
From Urban Vulnerabilities to Resilience: Lessons from Messina's Integrated Risk Approach
Authors: Ferramosca Giovanna , Terracciano Anna
Published: December 2023

In the city of Messina, the multiplicity of vulnerable situations is a distinctive feature and is representative of the pervasiveness of the risk conditions present in the Italian territory. The critical residential tissues are part of an extended geography in which, to the conditions of seismic and hydro geomorphological vulnerability, are added additional criticalities including altered natural resources, abandoned infrastructure, brownfields, quarries, and unregulated landfills, etc. Despite this, for Messina, there is still no urban planning tool capable of interpreting in an integrated way the risks present, which instead continue to be addressed on an emergency basis and individually, without considering the interactions that are generated and of further damage. For these reasons, Messina was chosen as a prototypical case study, at the national level, to start an experimentation aimed at developing an urban planning tool capable of a new integrated approach to risk interpretation and management. In this process, a decisive role was aimed at building an updated knowledge of the territory through the identification of widespread critical conditions using multiple GIS tools and thanks to the interaction of some analytical-specialist readings from different sources. The results of this process are represented in a system of maps that are strongly integrated with each other and constitute a working document for the interdisciplinary group drafting the General Urban Plan.
Liveability Considerations: Towards Designing Sustainable Public Housing in Niger State, Nigeria
Authors: Haruna Paul Baba , Zubairu Stella , Olagunju Remi Ebenezer , Akande Oluwafemi Kehinde
Published: December 2023

This study investigates liveability in the context of sustainable public housing in Niger State, Nigeria, where existing housing efforts have fallen short of residents' satisfaction. Recognizing the critical link between liveability indicators and environmental sustainability, this research aims to identify key liveability variables that could be integrated into the design and construction of sustainable public housing. Employing a mixed-method approach, the study involved cluster sampling for selecting housing estates and units, followed by the administration of 910 questionnaires containing 102 questions on liveability variables. Analytical techniques, including Hierarchical Cluster Analysis, Factor Analysis, and Multiple Regression Analysis, were used to group, refine, and validate the liveability variables. The results revealed 21 significant variables that collectively could achieve a 92.9% satisfaction rate among residents if incorporated into public housing design. These findings underline the potential of addressing liveability in the pursuit of sustainable housing solutions, offering insights for urban planners, architects, and policymakers. By focusing on the residents' perspectives, the study contributes to a more user-centred approach in public housing development, promoting long-term satisfaction and reducing the need for post-occupancy alterations.
Pelatihan Senam Pencegahan Osteoporosis dan Penyuluhan Kesehatan Gigi Mulut pada Masyarakat Pre dan Lanjut Usia Anggrek 3
Authors: Astuti Luki , Hanin Isya , Aryadi  , Tanjung Rizki
Published: December 2023

Living a healthy life as a senior is the desire of everyone. However, keeping an elderly healthy is not easy. There are many challenges to face, because the elderly are susceptible to a variety of diseases. As you age, your body undergoes many changes or aging processes, and the changes you feel cover the entire limb. Vascular problems such as hypertension and other heart problems are common. Not only that, the elderly are also at risk of suffering from bone diseases such as osteoporosis, which can be dangerous because it can result in bone fractures and inhibit the activity of the elders because they have to lie more. Osteoporosis is often associated with periodontitis, as both are diseases of the bone caused by inflammation and old age. Both osteoporosis and periodontitis have similar risk factors such as smoking, poor nutritional status, age and immune deficiency. Osteoporosis can be prevented by eating foods rich in calcium, avoiding smoking and alcoholic beverages, having regular and regular physical activity, and exposure to sufficient sunlight. Preventing osteoporosis can reduce the risk of periodontitis in the elderly. This  community service (PkM) is held for the elderly living in Grand Depok City Depok Residential, West Java. It is hoped that these activities will raise awareness of the elderly in particular, and the general public of the importance of health. It is expected that osteoporosis gymnastics for the elderly can be performed on a regular basis at Posbindu Anggrek 3.
Penyuluhan Penanganan Kedaruratan Gigi dan Mulut Terhadap Anak Usia Sekolah pada Orang Tua dan Guru SDI Al-Ikhlas Cipete - Jakarta Selatan
Authors: Wirahadikusumah Andy , Teguh Sharren , Juliani Hardja Buntara Magdalena , Sandra Ferry , Cloudya Panjaitan Caesary
Published: December 2023

Dental emergency is associated with immediate measures that are carried out with the aim to alleviate pain. Dental trauma is one of dental emergencies, which is injury to the teeth and or the supporting tissues of the teeth. Dental injuries are often experienced by school-aged children, in which the majority of traumatic dental injuries occur at home or school, hence it is hoped that parents and school teachers can provide appropriate treatment when dental emergencies occur in children. This community service counseling aims to increase knowledge and skills in the management of dental emergencies. Counseling was carried out by the Trisakti University Faculty of Dentistry Team to parents and teachers of Al-Ikhlas Islamic Elementary School, Cipete, Jakarta Selatan on March 11, 2023. Counseling includes learning materials regarding the management of dental emergencies and dental health education through powerpoint presentation, video, and live demonstration. Final questionnaire shows an increase in knowledge and understanding regarding the management of dental emergencies. Therefore, it can be concluded that after the counseling activity, there is an increase in the level of knowledge among parents and teachers of Al-Ikhlas Islamic Elementary School regarding the management of dental emergencies. Further training is needed to improve the ability to handle dental emergencies better.
JOURNALISTS OR INFLUENCERS? THE APPROPRIATION OF DIGITAL INFLUENCERS PRACTICES AS A TOOL OF JOURNALISTIC VALUE
Authors: Karhawi Issaaf , Camargo Isadora Ortiz de
Published: December 2023

This article answers two main questions: What are the similarities and differences between journalists' online practices and that of digital influencers’? How have social media and the intimate perspective shortened the distances between journalists and their audience? To understand this scenario, a trio of Brazilian television journalists was investigated to comprehend their digital presence. The authors elaborated an exploratory methodology for qualitative analysis of Instagram publications. Based on elements that characterize the digital influencers and journalistic practices, a score was also created to understand the potentials of their discourse, performances and content strategies online.
SOCIAL CAPITAL IN KNOWLEDGE MANAGEMENT SYSTEMS FOR THE CREATIVE INDUSTRY SECTOR
Authors: Khaksar Amin
Published: December 2023

The primary aim of this scholarly article is to examine the significance of social capital within the context of knowledge management systems (KMS) in the creative industry literature. The research adopts a comprehensive approach by employing both conceptual and literature analysis and empirical quantitative and qualitative investigations for validation purposes. According to existing literature, KMS is an essential organizational process and tool for acquiring, converting, applying, and safeguarding knowledge from internal and external sources, facilitating its utilization, development, and effective management.

The findings of this study reveal that specific organizations acquire knowledge primarily through internal research and development (R&D) processes. However, in contrast, the creative industry heavily relies on knowledge stemming from social capital, including the social environment and community interactions. This social capital plays a pivotal role in providing the necessary knowledge required for the existence of the creative industry and its ability to generate innovative products that reflect the prevailing social context within which it operates. To analyze and classify prior research on the role of social capital for KMS in the creative industry, this study utilizes a meta-analysis as a robust analytical tool, building upon earlier works that have served as foundational pieces for this investigation.

Previous research in the creative industry has demonstrated that knowledge acquisition within this domain results from a synergistic interplay between tacit knowledge and explicit knowledge obtained through diverse creative classes conducted within the industry. As a renewable resource-driven sector, the creative industry capitalizes on creativity, skill, and talent as valuable assets that can be leveraged for wealth generation, not only for significant enterprises but also for micro, small, and medium economies (UMKM), often orchestrated by local communities. This endeavor aims to stimulate employment opportunities by strategically exploiting intellectual property. Consequently, the creative industry can be regarded as a knowledge-based sector, necessitating the adept implementation of Knowledge Management Systems (KMS) in its operational framework.