bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis and Antioxidant Properties of Organoselenium Compounds
Authors: Mamgain Ritu , Kostic Marina , Singh Fateh V.
Published: August 2022

Background:

The chemistry of organoselenium reagents provides an asset for
organic synthesis. The versatility of these reagents as electrophiles and nucleophiles
makes them one of the key components of organic synthesis. Various synthetic transformations
such as oxyselenenylations, selenocyclization and selenoxide elimination have
been successfully achieved using organoselenium reagents under mild reaction conditions.
The presence of selenocysteine in a few mammalian enzymes was the key information for
selenium chemists to explore the biochemistry of selenium compounds. Glutathione peroxidase
(GPx), a mammalian selenoenzyme, is well known for maintaining redox equilibrium
by detoxifying reactive oxygen species.

Objective:

The aim is to critically analyze the recent development and prospects of synthesis
and antioxidant properties of organoselenium compounds.

Method:

In this review, we summarised research and review papers from the PubMed
and Scopus databases. The primary themes were linked to the synthesis of organoselenium
compounds and their capacity to maintain cellular redox equilibrium when exposed to
oxidative stress.

Result:

The study reveals that diselenide compounds synthesised by various methods
showed a better antioxidant activity profile compared to selenides. In a few cases, the
activity was found better than the standard compound ebselen. Moreover, the synthesis
and antioxidant activity of Selenium-based nanoparticles have been also included.

Conclusion:

In the past two decades, various biological properties of organoselenium
compounds have been extensively studied, including the antioxidant properties. This review
article will give insight into the synthesis of different types of recently synthesised
organoselenium compounds. The review would be helpful to the researchers working in
the field of medicinal chemistry in directing the synthesis of new organoselenium compounds
as antioxidants.
A Recent Update on the Epigenetic Repertoire and Chromatin Modifying
Therapy in Diabetes Mellitus: A Comprehensive Review
Authors: Wang Xin , Zhao Di , Beeraka Narasimha Murthy , Tatineni Spandana , Sri Chiriki Devi , Nishanth Veera Venkata , Uthiah Chinnappa Apatira , Leihang Zonunsiami , Sugur Kavya , Liu Junqi , Nikolenko Vladimir Nikolaevich , Fan Ruitai
Published: August 2022

Several epigenome studies reported the ability of genes to modulate the lipogenic
and glucogenic pathways during insulin signaling as well as the other pathways involved
in cardiometabolic diseases. Epigenetic plasticity and oxidative stress are interrelated
in the pathophysiology of insulin resistance (IR) and cardiometabolic disease conditions.
This review aims to ascertain the previous research evidence pertaining to the role
of the epigenome and the variations of histone and non-histone proteins during cardiometabolic
disease conditions and insulin signaling to develop effective disease-based
epigenetic biomarkers and epigenetics-based chromatic therapy. Several public databases,
including PubMed, National Library of Medicine, Medline, and google scholar, were
searched for the peer-reviewed and published reports. This study delineates the consistent
body of evidence regarding the epigenetic alterations of DNA/histone complexes
pertinent to oxidative stress, insulin signaling, metabolic cardiomyopathy, and endothelial
dysfunction in patients with cardiometabolic diseases. It has been described that both
DNA methylation and post-translational histone alterations across visceral and subcutaneous
adipose tissue could facilitate gene transcription to modulate inflammation, lipogenesis,
and adipogenesis as the complex network of chromatin-modifying enzymatic proteins
involved in the defensive insulin signaling across vasculature in patients with cardiometabolic
diseases. Resveratrol, vorinostat, trichostatin, and apabetalone are reported
to have significant implications as epigenetic modulators. Based on the epigenetic alterations,
a wide range of protein/gene markers, such as interleukin-4 (IL-4) and interferon-γ
(IFNγ) genes, may be considered as biomarkers in these patients due to their ability to
the polarization of immune cells involved in tissue inflammation and atherosclerosis.
Hence, it is crucial to unravel the cell-specific epigenetic information to develop individual
risk assessment strategies for chromatin-modifying therapies in patients with cardiometabolic
diseases.
Herbal Medicines as Potential Inhibitors of SARS-CoV-2 Infection
Authors: Rostami Soodabeh , Gharibi Shima , Yaghoobi Hajar , Nokhodian Zary , Shoaei Parisa , Bahrami Armina Alagheband , Ahangarzadeh Shahrzad , Alibakhshi Abbas
Published: August 2022

Coronavirus disease 2019 (COVID-19) is the result of infection with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). Understanding molecular pathogenesis is an essential factor for the allocation
of effective preventive measures and the development of targeted therapeutics against COVID-19. The
genome of SARS-CoV-2 encodes structural and nonstructural proteins, which can be targets for compounds
with potential therapeutic ability. On the other hand, the virus life cycle has stages susceptible to targeting by
drug compounds. Many natural antiviral compounds have been studied and evaluated at the cellular and molecular
levels with antiviral potential. Meanwhile, many studies over the past few months have shown that plant
polysaccharides have a good ability to target proteins and stages of the virus life cycle. In this regard, in this review
study, the virus specifications and infectious process and structural and functional components of SARSCoV-
2 will be reviewed, and then the latest studies on the effect of plant compounds with more focus on polysaccharides
on viral targets and their inhibitory potential on the infectious process of COVID-19 will be discussed.
Isolation and Identification of Bioactive Compounds with Antimicrobial
Activity from Marine Facultative Anaerobe, Bacillus subtilis
Authors: Marappan Makesh , Kotakonda Muddukrishnaiah , Dharmar Prabaharan , Sakthivel Balasubramaniyan , Sunnapu Prasad
Published: August 2022

Introduction:

The marine ecosystem contains many microbial species that produce
unique, biologically active secondary metabolites with complex chemical structures. We aimed to
isolate and identify bioactive compounds with antimicrobial properties produced by a facultative
anaerobic strain of Bacillus subtilis (AU-RM-1), isolated from marine sediment.

Methodology:

We optimized the AU-RM-1 growth conditions, analyzed its growth kinetics and its
phenotypic and genotypic characteristics. Extracts of the isolate were studied for antimicrobial
activity against three clinically important microorganisms and the structure of the active compound
was identified by spectroscopy.

Results:

Antimicrobial activity of the AU-RM-1 DMSO extract was evaluated by disc diffusion
assay and by serial dilution. The AU-RM-1 DMSO extract showed antimicrobial activity against
Candida albicans, Escherichia coli, and Klebsiella pneumoniae. The bioactive fraction of the AURM-
1 DMSO extract was separated by TLC-bioautography at Rf = 0.49. We then used scanning
electron microscopy (SEM) and transmission electron microscopy (TEM) to study the morphological
changes in the bacterial cells treated with the isolated compound. It was observed that cells
seemed to shrink, and the cell walls appeared to be damaged. A bioactive compound was identified,
and its structure was examined by spectroscopic analysis: a LC-MS molecular ion peak (ESI)
m/z (% of relative abundance) was calculated for C19H22O3: 298.38, and found to be C19H22O3
+1:
299.51 [M+1]. The chemical structure of the compound (2-(2-{8-methoxy-5aH,6H,7H,8H,9H,
9aH-naphtho[2,1-b]furan-7-yl}ethyl)furan) was determined using 1HNMR and 13CNMR, and its
purity was confirmed by HPLC. Fifteen known and previously reported compounds were also
identified, in addition to the novel compound; these were lipopeptides, antibiotics and chemical
moieties.

Conclusion:

The facultative anaerobic marine organism Bacillus subtilis (AU-RM-1) produces a
novel bioactive secondary metabolite with antimicrobial and antifungal activity.
An Overview Regarding Pharmacogenomics and Biomarkers Discovery:
Focus on Breast Cancer
Authors: Scandolara Thalita Basso , Barreto Pires Bruno Ricardo , Vacario Beatriz , de Amorim Isis Salviano Soares , Siqueira Priscyanne Barreto , Serpeloni Juliana Mara , Mencalha André Luiz , Bonvicino Cibele Rodrigues , Panis Carolina
Published: August 2022

Breast cancer represents a health concern worldwide for being the leading cause of can-cer-related women's death. The main challenge for breast cancer treatment involves its heterogene-ous nature with distinct clinical outcomes. It is clinically categorized into five subtypes: luminal A; luminal B, HER2-positive, luminal-HER, and triple-negative. Despite the significant advances in the past decades, critical issues involving the development of efficient target-specific therapies and overcoming treatment resistance still need to be better addressed. OMICs-based strategies have marked a revolution in cancer biology comprehension in the past two decades. It is a consensus that Next-Generation Sequencing (NGS) is the primary source of this revolution and the development of relevant consortia translating pharmacogenomics into clinical practice. Still, new approaches, such as CRISPR editing and epigenomic sequencing are essential for target and biomarker discoveries. Here, we discuss genomics and epigenomics techniques, how they have been applied in clinical management and to improve therapeutic strategies in breast cancer, as well as the phar-macogenomics translation into the current and upcoming clinical routine.
Childhood Obesity: An Updated Review
Authors: Leung Alexander K.C. , Wong Alex H.C. , Hon Kam Lun
Published: August 2022

Background:

Childhood obesity is an important and serious public health problem worldwide.

Objective:

This article aims to familiarize physicians with the evaluation, management, and prevention of childhood.

Methods:

A PubMed search was conducted in May 2021 in Clinical Queries using the key terms "obesity" OR “obese”. The search included clinical trials, randomized controlled trials, case control studies, cohort studies, meta-analyses, observational studies, clinical guidelines, case reports, case series, and reviews. The search was restricted to English literature and children. The information retrieved from the above search was used in the compilation of the present article.

Results:

Most obese children have exogenous obesity characterized by a growth rate for height above the 50th percentile, normal intelligence, normal genitalia, and lack of historical or physical evidence of an endocrine abnormality or a congenital syndrome. Obese children are at risk for dyslipidemia, hypertension, diabetes mellitus, non-alcoholic fatty liver disease, obstructive sleep apnea, psychosocial disturbances, impaired quality of life, and shorter life expectancy. The multitude of serious comorbidities necessitates effective treatment modalities. Dietary modification, therapeutic exercise, and behavioral modification are the fundamentals of treatment. Pharmacotherapy and/or bariatric surgery should be considered for obese individuals who do not respond to the above measures and suffer from a serious comorbid condition.

Conclusion:

Childhood obesity, once established, is often refractory to treatment. Most treatment programs lead to a brief period of weight loss followed by rapid re-accumulation of the lost weight after termination of therapy. As such, preventive activity is the key to solve the problem of childhood obesity. Childhood obesity can be prevented by promoting healthy diet, regular physical activity, and lifestyle modification. Parents should be encouraged to become involved in school and community programs that improve nutritional status and physical activity in their children.
Artificial Intelligence in Accelerating Drug Discovery and
Development
Authors: Tripathi Anushree , Misra Krishna , Dhanuka Richa , Singh Jyoti Prakash
Published: August 2022

Drug discovery and development are critical processes that enable the treatment
of wide variety of health-related problems. These are time-consuming, tedious, complicated,
and costly processes. Numerous difficulties arise throughout the entire process of drug
discovery, from design to testing. Corona Virus Disease 2019 (COVID-19) has recently
posed a significant threat to global public health. SARS-Cov-2 and its variants are rapidly
spreading in humans due to their high transmission rate. To effectively treat COVID-19,
potential drugs and vaccines must be developed quickly. The advancement of artificial intelligence
has shifted the focus of drug development away from traditional methods and
toward bioinformatics tools. Computer-aided drug design techniques have demonstrated
tremendous utility in dealing with massive amounts of biological data and developing efficient
algorithms. Artificial intelligence enables more effective approaches to complex
problems associated with drug discovery and development through the use of machine
learning. Artificial intelligence-based technologies improve the pharmaceutical industry's
ability to discover effective drugs. This review summarizes significant challenges encountered
during the drug discovery and development processes, as well as the applications of
artificial intelligence-based methods to overcome those obstacles in order to provide effective
solutions to health problems. This may provide additional insight into the mechanism
of action, resulting in the development of vaccines and potent substitutes for repurposed
drugs that can be used to treat not only COVID-19 but also other ailments.
The Multifaceted Interface Between the Host Immune Cell and Mycobacterium Tuberculosis - Mitochondria at the Crux of the Matter
Authors: Santos Dilvani Oliveira , Zuquim Antas Paulo Renato
Published: August 2022

Tuberculosis (TB) is a contagious infectious disease that is a major cause of
morbidity, being one of the top 10 causes of death worldwide, and the leading one from
a single infectious agent. Also called “White Plague” in the past, TB is an airborne
disease, propagated when multibacillary people spread M. tuberculosis by coughing or
sneezing. The disease typically affects the lungs (pulmonary TB), but can also affect
other sites (extrapulmonary TB). TB is curable and preventable: about 85% of the
people who develop the disease may be successfully treated with a 6-month multidrug
regimen. The treatment has the additional benefit of preventing onward transmission.
Macrophages are the first host cell to get in contact with M. tuberculosis. They also
have important effector functions, regardless of whether the infection evolves to a
chronic or latent form. However, M. tuberculosis evades host cell innate defense
mechanisms, manipulates organelles and cell metabolism, as well as host cell death
pathways. This complex interaction between the host cell and the bacillus determines
the outcome of the infection. In this context, mitochondria and mitochondrial DNA
(mtDNA) contribute to triggering cell death by necrosis. However, excessive necrosis
may lead to tissue damage, which disrupts granulomas and benefits M. tuberculosis
transmission. We intend to revisit the major aspects of this intricated and multifaceted
interface between the host immune cell and M. tuberculosis and discuss how
mitochondria are the crux of the matter
PENGARUH DUKUNGAN SOSIAL DAN HARAPAN TERHADAP RESILIENSI PADA MAHASISWA DIMASA PANDEMI COVID-19
Authors: Febriana Layla Ika
Published: August 2022

Pandemi covid-19 dalam pembelajaran secara online membuat mahasiswa membutuhkan dukungan sosial yang lebih dari orang terdekatnya untuk tetap dapat mempertahankan harapan yang telah dimiliki jauh sebelum pandemi covid-19 datang, sehingga daya reseliensi yang dimiliki dapat bertahan dengan baik. Subjek penelitian ini mahasiswa aktif S1, berjumlah 260 orang mahasiswa. Analisis regresi ganda digunakan untuk menguji hipotesis dalam penelitian ini. Hasil penelitian menunjukkan bahwa terdapat pengaruh yang signifikan terhadap nilai R2 sebesar 0,528. Hal ini berarti 52,8% variabel resiliensi pada mahasiswa dimasa pandemi covid-19 dapat dijelaskan oleh variabel dukungan sosial dan harapan, sedangkan sisanya 47,2% dipengaruhi dari faktor lain diluar penelitian dengan nilai Sig. 0,000 ( Sig. < 0.05).
STUDI KUALITATIF GAMBARAN KEPUASAN WANITA INDONESIA ATAS UKURAN PAYUDARA: FAKTOR SOSIAL & DAMPAK PSIKOLOGISNYA
Authors: Yumni Syarafina Zata , Putri Cindy Tiara , Mamarimbing Naomi Marsha Abigail
Published: August 2022

Ketidakpuasan wanita akan bagian tubuhnya dapat berdampak buruk pada kualitas hidup dan beberapa masalah psikologis lainnya. Salah satu bentuk ketidakpuasan yang dialami oleh banyak wanita adalah terkait ukuran payudara yang secara natural dimilikinya. Tujuan dari penelitian ini adalah untuk mengetahui gambaran kepuasan wanita Indonesia atas ukuran payudara yang mereka miliki secara natural beserta faktor sosial yang dapat memengaruhi rasa kepuasan tersebut dan dampak psikologis yang dirasakan sebagai akibatnya. Penelitian ini menggunakan pendekatan kualitatif pada sembilan wanita Indonesia yang dipilih dengan metode convenience sampling. Kriteria partisipan yang diambil adalah wanita berusia 18-24 tahun. Pengambilan data dilakukan dengan wawancara mengenai faktor sosial yang memengaruhi kepuasan partisipan akan ukuran payudaranya dan dampak psikologis yang dirasakan sebagai akibat kepuasan ataupun ketidakpuasannya. Data pada penelitian ini dianalisis dengan cara mengkoding jawaban partisipan berdasarkan analisis tematik. Adapun hasil dari penelitian ini adalah terdapat dua faktor sosial yang memengaruhi kepuasan wanita akan ukuran payudaranya, yaitu pengalaman yang baik dan paparan media sosial. Dampak psikologis yang dirasakan karena rasa puas tersebut adalah meningkatnya self-esteem, kepuasan akan penampilan, dan kepercayaan diri. Sedangkan faktor sosial yang memengaruhi ketidakpuasan wanita akan ukuran payudaranya adalah pengalaman buruk, paparan media sosial, standar kecantikan, dan konstruksi sosial terkait gender. Ketidakpuasan tersebut berpengaruh pada beberapa dampak psikologis seseorang, diantaranya adalah rasa keberhargaan diri, rasa tidak percaya diri, ketidakpuasan akan penampilan, kecemasan, dan trauma.
Patrones de actividad de mamíferos medianos en fragmentos de bosque de Marquetalia (Caldas, Colombia)
Authors: Fonseca Prada Katiuska Andrea , Botero Henao Nicolás , Mendoza Mora Alexander , Tunarrosa Echeverría Eliana Marcela
Published: August 2022

Los patrones de actividad constituyen un aspecto importante del comportamiento y la ecología de los mamíferos, y su estudio puede ofrecer información relevante para su conservación; no obstante, este tema ha sido poco estudiado en múltiples especies neotropicales. Con el fin de entender estos patrones, el fototrampeo se destaca como una de las técnicas que permiten obtener información de diversas especies de mamíferos, incluyendo algunas difíciles de registrar o estudiar con otros métodos. En el presente estudio, documentamos información sobre los patrones de actividad de diez especies de mamíferos medianos registrados en fragmentos de bosque en Marquetalia (Caldas), municipio ubicado en los Andes centrales, cuyos ecosistemas naturales enfrentan diversas amenazas como la expansión de los territorios agrícolas y ganaderos y la urbanización. Para ello se instalaron cámaras trampa en tres fragmentos de bosque y se analizaron los datos de acuerdo con la frecuencia de registros obtenidos a través del día, clasificando las especies como diurnas, nocturnas o crepusculares. Para las especies con el mayor número de registros (Didelphis marsupialis, Dasyprocta punctata y Syntheosciurus granatensis) se graficó el patrón diario de actividad, evidenciando poca variabilidad frente a lo reportado por otros autores en áreas con diversos grados de intervención. Estos hallazgos son relevantes para contribuir a entender algunos de los factores que influyen sobre aspectos comportamentales de los mamíferos terrestres y la influencia de diversas presiones y amenazas sobre éstos.
Incentivizing Alternative Fuel Vehicle Transactions: Analysis of Cash-for-Clunkers Transactions for New Alternative Fuel Vehicles
Authors:   Schar School of Policy and Government, George Mason University, Arlington, VA 22201 USA, Zolnik Edmund
Published: August 2022

Monetary incentives to accelerate the transition of private vehicle fleets to zero emissions promote sustainability in the transportation sector. Clean Cars for America to incentivize transactions for new battery power vehicles is a program in furtherance of sustainable transportation goals in the United States. Unfortunately, data on transactions for new alternative fuel vehicles (AFVs) are scarce so empirical research to explore the costs and/or the benefits of such programs is also scarce. Analysis of transactions for new AFVs from a past, national vehicle retirement program known as Cash for Clunkers provides a rare glimpse into the economic costs and into the environmental benefits of monetary incentives. Analysis of transactions for new AFVs also provides an empirical context for a future, national retirement program such as Clean Cars for America. To that end, the analysis estimates Greenhouse Gas (GHG) emission reduction from a subsample of Cash-for-Clunkers transactions for new AFVs. Overall, incentivizing AFV transactions effectively decreases GHG emissions though regional differences may necessitate dynamic, rather than static, voucher amounts so as to harmonize such differences.
DO AUTONOMY SUPPORTS IMPROVE MEDICAL STUDENTS’ MOTIVATION IN A DEVELOPING COUNTRY?
Authors: Nugraheni Elizabeth Sulastri , Widyandana Doni , Hidayah Rachmadya Nur
Published: August 2022

Background: Medical students in private schools are mostly high school graduates, ages are around 17 to 18. They were so diverse, the background of the former school, culture, motivation, and study skills. Students from rural might have different motivation and study skills from students of big cities. To give autonomy support to the new medical students, we planned the motivational workshop and study skills mentoring. We assume those will increase their motivation.Aims: To know - What types of motivation do first-year medical students have? Secondly, to evaluate - Whether motivational workshops and mentoring about study strategies can help to increase students’ autonomous motivation based on the Self-Determination Theory.Methods: A mixed-methods research was conducted in this study. The first step was the quantitative study using the Academic Motivation Scale (AMS) to measure the students’ pre and post intervention motivation and the Intrinsic Motivation Inventory (IMI) post intervention, then followed by the qualitative study to capture students’ responses and reflections with convenience sample.Results: The autonomous motivation was high among the male students, home-schooling, does not belong to medical profession family, and students from lower middle income. Quantitative data showed that this approach significantly decreased the amotivation scale of participants (p=0.025). Descriptively, there was an increase in the autonomous motivation of participants after following motivational workshop and study strategies mentoring.Conclusion: Motivational workshops and mentoring on study strategies were found to be valuable, interesting, and facilitate autonomous motivation. Results showed that those activities increased the students’ autonomous motivation.
Equality Agenda Sustainable Development Goals and Muslim Countries’ Acceptance For LGBTQ
Authors: Nurdyawati Tika Tazkya , Mardiah Anne , Rizal Raden Radhitya
Published: August 2022

Sustainable Development Goals are the agendas that formulated by world leaders that aim to reduce and protect the collective global world. One of its points is to seek gender empowerment in the 5th point of the SDGs. Many narratives related to the rights of the LGBTQ community often occur and even experience threats in several Islamic countries that still adhere to Islamic sharia. This article aims to examine how the SDGs can influence Muslim countries’ policies towards the acceptance LGBTQ community in their country. This article uses Robert Dahl's one-dimensional power concept. This research uses a qualitative approach and collects the data taken from many sources to be analysed by Atlas.ti application. The findings from this research are the fact that the 5th point of SDGs agenda still cannot be implemented in Muslim countries’ policy for accepting the LGBT community because it collides with sharia law that has been held for a long time. The pros and cons are indeed a very natural thing, and first the SDGs agenda cannot immediately change the policies that have existed for a long time, especially those related to the ideology of a country that forbids LGBT.
A Study of Gurnah’s Memory Narrative and Diaspora Identity
Authors: Du Yujin , Cui Dan
Published: August 2022

The Nobel Prize for Literature has been won by 70-year-old Tanzanian novelist Abdulrazak Gurnah for “his uncompromising and compassionate penetration of the effects of colonialism and the fate of the refugees in the gulf between cultures and continents”. “Refugees” highlights the issue of identity, while the transferring of cultural continent highlights diaspora, and memory narrative is a characteristic of his writing, which can be adopted to explore the symptoms of identity exfoliation and diaspora. This paper, by focusing on the theories of memory and diaspora identity from the perspective of Gurnah’s memory narrative, aims to explore the racial identity, focusing on the antagonism and hatred between races in the post-colonial context, the hybrid identity in the context of family diaspora, the social identity in the context of group culture, and the female identity in the development of individuality.Memory is an important texture that underlines Gurnah’s writing and his perception and deep thinking on identity provides a multidimensional entry point for the international literary world with unique personal characteristics and humanistic care in the global context. Racial identity, focusing on the antagonism and hatred between races; hybrid identity, the impotence of immigrants, unable to establish their own identity; social identity, the alienation of marginalized people and the young generation’s powerless sense of colonial culture; female identity, women’s weightlessness under gender pressure.
Tranquilizing Forgivable Feuds between Frank Chin and Maxine Hong Kingston to Establish the Group Identities of Chinese Americans
Authors: Yinhua He , Jun Luo
Published: August 2022

In the midst of seeking for the true cultural identification of entire Chinese Americans, imaginative discrepancies cropped up in the actual aesthetic and artistic production of Chinese American literature due to the inconsistent insistence of the cultural stances exemplified in the aesthetic and artistic articulation of the true cultural values and cultural virtues in the diverse and distinctive production of Chinese American literary works. Among those discrepancies between either two of various Chinese American writers, those between Frank Chin and Maxine Hong Kingston has stirred a great sensation in the forum of Chinese American literature because of the persistence of the former in positive protection of the masculinity of Chinese American men and the ongoing insistence of the latter on the negative promotion of it from the perspective of feminism without knowing in a very clear fashion that their inconsistence led to the strong feud between them and the harm it has done to the establishment of the cultural identity of Chinese Americans. Indebted to the insights carried in the group identities proposed by Henry Tajfel and John Turner (1979), this article will make a rational comparison between what they have sticked to in a respective fashion and come up with the point that the feud between them are forgivable and forgettable as what they have done is very valuable for the improvement of the true social, cultural, and, ethnic identities of Chinese Americans who are composed of both Chinese American men and Chinese American women to deal with the great danger into which all Chinese Americans have been thrown into due to the excessive popularization of the social, cultural, and, ethnic discrimination of the entire ethnic group of Chinese Americans in Chinese American community.
ASSESSMENT OF LAPAROSCOPIC APPENDECTOMY IN PATIENTS OF COMPLICATED APPENDICITIS IN TERTIARY CARE TEACHING HOSPITAL OF CENTRAL INDIA
Authors: AKHILESH KUMAR YADAV  , SHIV KUMAR YADAV  , PIYUSH KUMAR SINHA  , DWIVEDI MK  , SUNIL KUMAR SINGH  , RAHUL RANJAN
Published: August 2022

Background: Appendicitis is the commonest abdominal surgical emergency in the world which may lead to complications like appendicular abscess or mass, gangrene, perforation and peritonitis. Present research aimed to evaluate the wellbeing and the effectiveness of laparoscopy for managing complicated appendicitis.

Material and methods: Present study was carried out on 50 patients at tertiary care institution of Chhattisgarh in Central India for the period of 2 year. This study is including patients of complicated appendicitis undergoing laparoscopic management. Parameters studied included Age, Gender, WBC count, wound infection and hospital stay.

Results: There was increase of total leucocytic count in most of the patients; Mean WBCs was 12.71±5.37. 33 patients had pus free IPF collection and perforated appendicitis (PA), 11 patients had turbid free IPF collection with AA (highly inflamed appendix), 2 case was mucocele of the appendix, 2 cases of appendicular abscess (3.3%) and 2 cases of gangrenous appendix.

Conclusion: Management of complicated appendicitis laparoscopically is practicable, secure and can present a small occurrence of infectious impediments, fewer post-operative pain, fast revival and improved cosmesis on the cost of extended operating time than Open Appendectomy
Cobertura y composición arbórea en las áreas verdes de Hermosillo, Sonora: aportaciones al urbanismo sustentable
Authors: Ortega Rosas Carmen Isela , Martínez Salido Jazmín , Sánchez Duarte Nancy Esmeralda , Morales Romero Daniel
Published: August 2022

Objetivo: analizar la condición actual de los parques y jardines del municipio de Hermosillo, Sonora, teniendo en cuenta su cobertura arbórea y la proporción que hay entre las especies nativas y las especies introducidas. Metodología: se seleccionaron al azar espacios de jurisdicción municipal que tienen un área superior a 170 m2, donde se calcularon la cobertura arbórea, la cantidad de especies nativas y la de especies introducidas. Resultados: se constató la presencia de 29.2% de especies nativas y de 70.8% de especies introducidas. En ninguno de los espacios la cobertura arbórea superó 33%. Valor: se presenta información indispensable para el manejo del desarrollo urbano con enfoque en calidad ambiental. Limitaciones: no se incluyeron las áreas verdes de los fraccionamientos privados ni de los camellones públicos. Conclusiones: se demuestra que la condición actual es la falta de cobertura vegetal y la poca presencia de especies nativas en las áreas verdes urbanas y que necesitan recuperación ecológica para mejorar la calidad de vida poblacional.
Dynamics of a second order three species nonlinear difference system with exponents
Authors: Mathew Smitha Mary , Dilip D. S.
Published: August 2022

In this paper, we study the persistence, boundedness, convergence, invariance and global asymptotic behavior of the positive solutions of the second order difference system xn+1 = α1 + ae−xn−1 + byne−yn−1 , (0.1) yn+1 = α2 + ce−yn−1 + dzne−zn−1, zn+1 = α3 + he−zn−1 + jxne−xn−1, n = 0, 1, 2,.... Here xn, yn, zn can be considered as population densities of three species such that the population density of xn, yn, zn depends on the growth of yn, zn, xn respectively with growth rate b, d, j respectively. The positive real numbers α1, α2, α3 are immigration rate of xn, yn, zn respectively, while a, c, h denotes the growth rate of xn, yn, zn respectively, and the initial values x−1, y−1, z−1, x0, y0, z0 are nonnegative numbers.
Irony, Nostalgia, and the Postmodern: A Dialogue
Authors: Hutcheon Linda , Valdés Mario J.
Published: August 2022

Linda Hutcheon says that this article is a dialogue that was initially provoked by some ruminations on her part over why she had resolutely insisted that the postmodern was more ironic than nostalgic. This dialogue with Mario Valdés represents her attempt to deal with this unfinished business to try to understand why she had earlier chosen the nostalgic dimension of the postmodern in favor of the ironic. It also represents Valdés response to this position and his critical testing of it on the field of contemporary Spanish cinema.
Borges y Sartre: ¿senderos que se bifurcan?
Authors: Brescia Pablo A. J.
Published: August 2022

El autor propone un cruce imaginario entre Borges y Sartre, más imaginario que el que se dio en 1952 cuando Etiemble publicó en Les tempes modernes, la revista dirigida por Sartre, un ensayo que trazaba el elogio de la obra borgeana y su significado en las letras latinoamericanas. La supuesta divergencia en el uso del material filosófico y literario por parte de Borges y de Sartre constituye el punto de partida desde donde se intenta trazar una convergencia que considera el «primer» Borges y el «primer» Sartre, o sea, ciertos pasajes de su producción inicial.
Sara und Simón, de Erich Hackl: reflejo literario de las dictaduras latinoamericanas
Authors: Eckart Gabriele
Published: August 2022

Gabriele Eckart hace una comparación entre Sara und Simón de Erich Hackl y El Señor Presidente de Miguel Ángel Asturias, quienes reflejan con diferentes estrategias narrativas el mecanismo de las dictaduras latinoamericanas.
CertiSafe: A Blockchain Based Certificate Validation and Safety System
Authors: Samanthula Sri Bhuvaneswari
Published: August 2022

Abstract: In every career progression, we receive certificates of degrees and achievements. In the recent times as the technology advances, we also have people cheating by forging and duplicating certificates. We see people duplicating certificates by forging their names on the genuine certificates. As mostly institutions have digitalised the paper certificates and now by adding this system at the issuing and receiving party can make the entire process safe and reliable. This paper proposes a system where the issuing party of the certificate can use this system to safeguard the certificates from duplication and the third party or receiving party can reupload and check if the certificate is genuine and not tampered.
Consumer Preferences and Purchasing Pattern towards Fruits and Vegetables Purchased Through E-Commerce Sector
Authors: N Ms. Lavanya
Published: August 2022

Abstract: The present study “Consumer perception towards fruits and vegetables purchased through e-commerce sector” was aimed to identify the consumer preferences, purchasing pattern, faced by consumers during the purchase of fruits and vegetables through online. E-Commerce business of selling fruits and vegetables through internet has been recently introduced in some metropolitan cities. Online retail outlets of fruits and vegetables like ninjakart, bigbasket, Freshmigo, jiomart etc.., which have been expanding. A representative sample of 80 consumers from Bengaluru and Tirupati cities were selected purposively for the present study. The data collected was analysed using both quantitative and qualitative research techniques. Mainly the data collected was tabulated and analysed using appropriate statistical tools such as percentage analysis, likert scale analysis. Online shopping stores need to provide more variety and quality of products in order to attract more customers. New methods should be adopted by the companies to fulfil the requirements of the customers. It is required to provide a wide variety of products to satisfy the needs and wants of customers because consumers were not convinced with the range of product available with online stores. The staff in the fruits and vegetables division should be given appropriate training on handling perishables and presenting them without damp to customers all the time.
A Survey on Approach for Efficient and Secure Data Encryption Scheme for Spatial Data
Authors: D P Sneha
Published: August 2022

Abstract: In spatial applications location data of the users continuously processed in un-trusted servers, this may cause to user privacy. Location information of the users is very sensitive data like their meeting information, residential and official location information’s. In present solutions of the un-trusted servers may have the several problems and limitation like data security, data availability, request processing etc. In general cloud environment provides lot of features to solve many problems with low cost. Elastic cloud environment will provide successful solutions for spatial data and user’s data. Many security algorithms were proposed and for cloud data security and many Locations Based services (LBS) security functionalities were proposed in many researches. In this paper we survey on various secure location-based techniques and cloud data security architectures.
Review Study on Concept of Sharir in Ayurveda
Authors: Madhukar Dr. Lahange Sandeep
Published: August 2022

Abstract: The word 'Sharir' stands for Rachana (anatomy) along with Kriya (physiology). The science which deals with the knowledge of Sharir i.e. human body is called as Sharir. It is also known as Sharira Rachana Vigyana or Sharira Shastra. For better understanding of etiopathogenesis and treatment of various disorders, the knowledge of Sharir is absolute vital and necessary Ayurveda classics give emphasis on applied aspects of science and thus instead of describing micro structures, they described Sharir' wherever required. Birth i.e. Formation of fetus and diseases i.e. various Vikruti (deformities) or Vikara (diseases) which lead to destruction of the body; it is all mentioned in this part of the science. The detailed knowledge of the human body is necessary for the well-being of the body. After getting knowledge about the entities of the body, one is able to know about the factors which are useful to the body; hence the detailed knowledge of the body is recommended by the experts. The physician having good knowledge of Sharira can enlighten the Ayurveda for the welfare of the universe. In the knowledge of Ayurveda, Sattva, Aatma and Sharir- these three are tripods for the life. The entire universe is based on these three basic units. The Sharir a branch of medical science that deals with the structural and functional aspects of a living body is importance for the achievement of the goals of the medical branches and the prevention and the treatment of diseases of entire human kind.
Advancement in Diagnosis of Ovarian Cancer
Authors: Sijwali Jyoti
Published: August 2022

Abstract: Epithelial ovarian cancer is usually found in the advanced stage. The current state of the art surgery and chemotherapy leads to complete release; However, the repetition rate is high. in many patients, the disease ends up being a continuous period without symptoms and episodes of recurrence. A variety of targeted therapies and biological drugs, currently under development, offer the promise of transforming ovarian cancer, the latest major studies in a variety of new conventional therapies, and new therapies, recently approved and / or clinical trials
Efficacy of Bacterial Concrete with Conventional Concrete
Authors: Hritik Deore
Published: August 2022

Abstract: Concrete is one of the maximum used building substances. But, it is one of the predominant manufacturers of carbon dioxide (CO2) that's immediately contributing to destroying our surroundings. Not to say that significant costs are being spent each year to keep concrete structures. Cracks of numerous sizes shape in all concrete structures which need to be sealed manually shortening the life of a particular construction. However, Self-healing concrete (SHC) is a innovative constructing material that has the answer to these kind of troubles and is the constructing fabric of the near destiny. Therefore, we want to apprehend its homes and mechanism and foresee how it impacts the architectural designs of the time to come back, and which standers are had to create useful and aesthetic homes and buildings. It's been proven that a number of the present day concrete remedy strategies together with the software of chemical substances and polymers are a supply of fitness and environmental dangers, and greater importantly, they are powerful best within the quick term. As a result, treatment techniques which are environmentally pleasant and lengthy-lasting are in high call for. A microbial self-restoration method is distinguished by way of its capacity for long-lasting, fast, and lively crack restore, even as also being environmentally pleasant.
Hackers cívicos: tecnologias digitais como construção coletiva do meio urbano no Brasil
Authors: Fariniuk Tharsila Maynardes Dallabona , Firmino Rodrigo José , Luque-Ayala Andrés
Published: August 2022

Este estudo visa analisar teórica e conceitualmente o movimento civic hacking no Brasil, com base na diferenciação de tipologias e objetivos dos grupos na construção de ambientes urbanos digitais. A metodologia estabelece um levantamento empírico do fenômeno, seguido por agrupamento de conceitos e categorizações e pelo entendimento dos níveis de atuação da prática hacktivista, o que resultou em um modelo interpretativo que procura definir panoramicamente e de modo flexível a atuação do hackeamento cívico no Brasil. Observou-se que nesse contexto a prática hacker emerge como algo além da quebra de códigos, uma vez que passa a figurar como forma de subversão da utilização tradicional do digital, visibilizando e dando voz a diferentes narrativas. Concluiu-se que a lógica do “sistema a ser invadido” permanece, em alguma medida, de maneira empírica e iterativa, pautada nas tentativas, erros e improvisos.
Comprehensive Review on Phytosomes: A Novel Drug Delivery System of Phytoconstituents
Authors: Poudyal Abhilash , Subba Barsha , Bhattarai Abhishek , Regmi Dinesh , Tiwari Bishal , Pradhan Aditya , Bhutia Sonam
Published: August 2022

Phytosomes are referred to as novel compounds containing lipophiliccomplexes of components of different plants which are composed of glycerophospholipids. In the novel drug delivery system, it is a need of the hour to search for such a novel delivery system that can provide more bioavailability and efficacy for any extract containing phytoconstituents or Phyto extracts. The present study data were collected from extensive literature surveys from different esteemed scientific repositories such as Pubmed, Science direct, Research gate, Cochrane, Google scholar, Willey, Core, 1Library, etc. Many phytoconstituents that are obtained from nature have high biological activities in many chronic diseases and has the best therapeutic efficacy. The main advantage of using phytoconstituents is that it does not have most adverse side effects. Phytosome is used for phytopharmaceutical formulations, herbal formulations, and in Ayurveda. It improves the bioavailability of medicaments and absorption of drug molecules. It has a better pharmacokinetic and pharmacodynamic profile as compared to the normal traditional medicinal plant extracts. The objective of this comprehensive review work is, to provide a combination of all the scientific aspects regarding the phytosomes (phyto-phospholipids complexes) point of view that were missed by some articles by highlighting the history, technology, characterization, chemical properties, its preparation, formulation, interactions, solvents systems, therapeutic utilization with dosages forms, side effects, latest patented technology, the difference between phytosome and liposome, Phyto-phospholipid complexes, Lamellarity and Stability, Solubility and partition coefficient, SEM & TEM, FTIR spectroscopy, bioavailability, advantages, other lipid-based nano-carriers; similarities and differences, biological or pharmacological properties, interactions between active constituents and phospholipids, vesicular systems for phytosome development, commercial marketed phytosomes products, recent advancements and limitations in this review paper
CORPO-ESPAÇO AO CORPO-TERRITÓRIO
Authors: Oliva Victoria Ferreira
Published: August 2022

O presente artigo visa discutir sobre a renovação de conceitos e categorias centrais para a Geografia a partir de uma perspectiva que não seja somente feminista, mas também decolonial. Para isso, foi traçado um caminho que começa na crítica feminista à criação de um conhecimento não situado e universal. Alcança o debate sobre o corpo-espaço, que é trabalhado como uma primeira rodada de percepção entre a relação entre corpo e espaço em uma perspectiva feminista. Em seguida, um “giro descolonial” é proposto, apontando para uma relação coletiva entre o corpo e o território: o corpo-território, insígnia de feministas de base comunitária. Para isso, foi necessário realizar um denso levantamento bibliográfico sobre os conceitos de espaço, território e sobre a escala do corpo em suas epistemes, além das abordagens feministas, tanto as mais tradicionais, quanto as comunitárias (e outras dissidências).
El Seminario de Comillas y «el arte cristiano»
Authors: Aramburu-Zabala Higuera Miguel Ángel , Losada Varea Celestina
Published: August 2022

The construction of the Seminary of Comillas (1883-1893) is a spectacular late manifestation and adapted to the Spanish environment of what in Europe was known as the movement of «Christian Art», a declared «secession» of the development of contemporary artistic movements, considered by this movement as products of paganism, positivism or atheism. lnfluences of German and French «Christian Art», and a determined will to Spanishize the movement, come together in the Seminary of Comillas, under the spiritual and intellectual direction of the Society of Jesus and the patronage of the Marquises of Comillas, Antonio López y López and Claudio López Bru. To this is added the participation of a large group of Catalan architects and artists: Juan Martorel, Luis Doménech y Montaner, Cristóbal Cascante, Eduardo Llorens Masdeu, José María Tamburini, Juan Llimona, Eusebio Arnau… New documentation and a detailed analysis of the iconography and context of the artistic works of the Seminary provide a thorough explanation of each of them and of the whole of the Seminary, inserting it into the whole of Spanish and European art of the late nineteenth century.
“A Year in the North” by S.V. Maksimov as a Document of the Era
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Akimova Maria S.
Published: August 2022

The article is devoted to the history of S.V. Maksimov’s “literary expedition” to the North of the Russian Empire, which resulted in the book of essays “A Year in the North”, interesting from artistic and historical points of view. The book was written in the middle of the 19th century and recorded important events and phenomena of this period, which are of great ethnographic interest today. The article reveals the main stages of the expedition, its causes and results, the book “A Year in the North” is considered in the context of S.V. Maksimov’s era, as well as in the context of modernity.
Documentary in L.N. Tolstoy’s Folk Literature
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Sizova Irina I.
Published: August 2022

The article considers the correlation of documentary as a kind of fiction with folk works by L.N. Tolstoy. The biographical material shows how the writer creatively comprehends the key features of this genre: expresses the actual events, enriches the applied function of the document, captures in specific phenomena the socio-typical properties, aesthetically evaluates the depicted realities in historical perspective, reliably uses the facts, entiches poetic imagery with publicistic pathos, describes the wanderings of the characters.