bluuebunny/crossref_metadata_2025 huggingface dataset:
O ESTABELECIMENTO DO JUIZ DE GARANTIAS PELO PACOTE ANTICRIME: UMA BATALHA ENTRE PUNITIVISMO E DIREITOS FUNDAMENTAIS
Authors: Silva Ivan Luiz da , Lemos José Alexandre Silva
Published: November 2024

O presente artigo tem por objetivo analisar como as recentes alterações realizadas na legislação penal e processual penal, pela Lei nº 13.964/2019, denominada pacote anticrime, que estabeleceu, dentre outras medidas, o juiz de garantias, reforçam o sistema acusatório e densificam a proteção aos direitos fundamentais. Partiu-se da análise do contexto da elaboração da nova legislação e o efeito provocado pelo estabelecimento de novas garantias processuais que aumentam a imparcialidade do julgador no desenvolvimento do processo penal. Observou-se, contudo, a resistência de alguns núcleos de opinião, com influência nos meios de comunicação, notadamente nas redes sociais, que buscam limar os objetivos da novel legislação, sob o argumento de um afrouxamento no combate ao crime, de modo a mobilizar a opinião pública e exercer um fator de pressão social sobre os Tribunais. Diante de tal estado de coisas, necessário demonstrar a validade do juízo de garantias aliado ao aprofundamento da interpretação racional do direito, como forma de conter e limitar um ativismo judicial na seara do processo penal. A opção metodológica foi por uma pesquisa exploratória, descritiva e reflexiva, que recorreu à análise da revisão bibliográfica e análise documental, diante da necessidade de investigação em fontes de natureza teórica e em documentos legais.
APONTAMENTOS SOBRE A FLEXIBILIZAÇÃO DA REGRA DA IMPENHORABILIDADE SALARIAL
Authors: Silva José Erick Gomes da , Dantas Frederico Wildson da Silva , Araújo Aurélio Ramos de
Published: November 2024

O artigo examina a impenhorabilidade da remuneração do executado, debruçando-se sobre alguns dos seus principais aspectos: natureza jurídica, ônus da prova e posicionamentos doutrinários e jurisprudenciais sobre hipóteses de flexibilização dessa regra. Tem como objetivo, em suma, sistematizar o atual estágio da discussão acerca da aplicação do artigo 833, inciso IV, do Código de Processo Civil. Adota o método dialético e utiliza as técnicas de pesquisa bibliográfica e análise de jurisprudência para a exploração de argumentos distintos sobre o tema. Apresenta reflexões úteis tanto à práxis forense quanto ao aprofundamento teórico de estudos que se empenham no desvendar do sentido e do alcance de normas jurídicas que circunscrevem limitações à tutela jurisdicional executiva.
ENTRE A LÓGICA E A EXPERIÊNCIA: O CAMINHO DA NORMA JURÍDICA DE RESPONSABILIDADE TRIBUTÁRIA DO ADMINISTRADOR
Authors: Nunes Danyelle Rodrigues de Melo
Published: November 2024

O problema da presente pesquisa é: qual a espécie de responsabilidade tributária prevista no inciso III do artigo 135 do Código Tributário Nacional? Trabalha-se com a hipótese de que se trata de uma espécie de responsabilidade tributária subsidiária, por mais que o texto legal tenha conduzido a caminhos tão diversificados. Esse estudo tem o objetivo de descrever a teoria do filósofo Oliver Wendell Holmes Jr., a fim de revelar as nuances que acompanham a norma jurídica de responsabilidade tributária do administrador e propor uma interpretação que não se confunda com o interesse de certas categorias, mas que seja condizente com as demais normas do sistema, o contexto e a política de Estado. A metodologia utilizada foi a bibliográfica, do tipo dedutiva, tendo como referência as premissas instituídas na obra intitulada The Path of the Law. A conclusão é a de que a lógica e a experiência caminham juntas para a fundamentação e a legitimação da aplicação normativa, o que conduzem à responsabilidade tributária subsidiária do administrador.
A DEFINIÇÃO DA NATUREZA JURÍDICA DAS MEDIDAS PROTETIVAS DE URGÊNCIA PREVISTAS NA LEI N. 11.340/06 COMO PRESSUPOSTO PARA DEFINIÇÃO DO PROCEDIMENTO APLICÁVEL À ESPÉCIE
Authors: Tenório Marta Diana Lucindo , Paiva André Luís Parizio Maia
Published: November 2024

O presente trabalho visa discutir a natureza jurídica das medidas protetivas de urgência previstas na Lei n. 11.340/06, a fim de definir procedimento aplicável que se mostre mais consentâneo com o que dispõe a Constituição Federal e as leis infraconstitucionais que versem sobre prevenção e coibição à violência doméstica e familiar contra a mulher. A pesquisa se justifica pela necessidade de unificar o procedimento aplicável às medidas protetivas, de modo a assegurar maior segurança jurídica aos processos judiciais referentes à matéria e evitar a revitimização da mulher vítima de violência doméstica e familiar.
BOTULISMO EM BOVINO DE CORTE (Bos indicus) EM BRASÍLIA / DF – RELATO DE CASO
Authors: Mota Pablo Luiz Marins , Ferrer Daniela Mello Vianna , Mendes Fernando Luíz Fernandes , Fernandes Neto Nilo , Martins André Vianna
Published: November 2024

O botulismo é uma doença tóxica grave, não contagiosa, altamente letal, que acomete bovinos. Esta ocorre pela ingestão da toxina botulínica, tipo C ou D, que é formada por uma bactéria, Clostridium botulinum, que pode estar presente tanto no alimento quanto na água. É desenvolvido em ambientes de anaerobiose, como corpos de animais em decomposição que morrem próximo de aguadas ou no pasto, alimento podre ou em água parada, além da osteofagia em bovinos mantidos em áreas deficientes em fósforo, sem a adequada suplementação mineral. Esse trabalho visa relatar um caso de Botulismo em um bovino da raça Nelore em Brasília/DF, visando conscientizar a importância da prevenção e controle da doença no ponto de vista econômico. Um bovino, fêmea, 2 anos, foi encontrado isolado do rebanho com dificuldades para se levantar. Durante o exame foi constatado consciência normal, diminuição do tônus da língua e da cauda e temperatura corporal normal. Os animais roíam os ossos de animais mortos que ficavam pelo pasto e não eram vacinados para Botulismo. O diagnóstico foi confirmado através do exame laboratorial, da amostra de sangue e fezes, com resultado positivo para Clostridium botulinum tipo D. O animal veio a óbito. Para prevenção e controle, foi realizada a vacinação de todo o rebanho, o recolhimento de todos os ossos de animais que ficavam pelo pasto, enterrando-os em um local distante da propriedade. O botulismo causa diversos prejuízos econômicos, necessitando adoção de medidas preventivas como vacinação dos bovinos, remoção de carcaças, entre outros.
ELABORAÇÃO DE PRODUTO LÁCTEO DE CABRA ANÁLOGO AO DOCE DE LEITE COM ADIÇÃO DE XILITOL
Authors: Neves Victoria Gonzalez , Fernandes Thamara Dias , Ferrer Daniela Melo Vianna , Silva Polyanne Martins da , Bobany Denise de Mello
Published: November 2024

Com a demanda consumidora crescente vem aumentando a necessidade de novos derivados lácteos de cabra que sejam saudáveis e práticos. O objetivo do presente trabalho foi a elaboração de um derivado lácteo de cabra análogo ao doce de leite com a adição de xilitol, diminuindo os estigmas relacionados ao leite de cabra e mostrando como seus produtos podem trazer vantagens para a saúde do consumidor e ainda assim ser algo saboroso. Utilizando a metodologia empregada na produção do doce de leite, uma vez que não há regulamentação específica para o produto neste estudo, foram empregados bicarbonato de sódio, xilitol e leite de cabra em pó, resultando em um produto final satisfatório. A receita consistiu em 1 litro de leite de cabra, 13de xilitol e de bicarbonato de sódio, alcançando um rendimento final de 24%, totalizando 247g.
Percibiendo las invasiones biológicas: interés de las comunidades rurales en participar en programas de control comunitario de Pinus Radiata.
Authors:   , Sánchez Fuentes Pabla Catalina
Published: November 2024

Las zonas templadas se enfrentan actualmente a una crisis generalizada, relacionada con fenómenos climáticos extremos, sequías y graves incendios forestales que favorecen el establecimiento y la propagación de árboles no nativos invasores utilizados comercialmente, como el Pinus radiata, afectando tanto a la biodiversidad como al bienestar de las comunidades locales. Ante este escenario, es crucial comprender la percepción de los árboles invasores y el conocimiento que tienen las comunidades de las invasiones de árboles y plantas, así como su disposición a gestionarlas. El objetivo de esta investigación fue evaluar las características demográficas y los factores que influyen en la percepción e interés de las comunidades rurales de la zona central de Chile para participar en programas comunitarios de control de Pinus radiata; una especie invasora y comercial. Para ello, se realizaron 220 encuestas cara a cara en tres zonas rurales afectadas por incendios forestales de diferentes intensidades; Santa Juana (n=62), Constitución (n=78) y Tucapel (n=80).
Las comunidades que viven en las zonas afectadas por mega incendios forestales mostraron mayor interés en participar en estrategias comunitarias de control de Pinus radiata. También, las personas entre 25 y 50 años, las mujeres, quienes piensan que las especies no nativas impactan en la biodiversidad, quienes piensan que la presencia de Pinos afecta a las tradiciones de la comunidad y quienes creen que la responsabilidad del control es individual, estatal y empresarial. Mientras que, quienes se benefician del uso de los pinos como combustible, material de construcción y zonas recreativas mostraron bajo interés. Nuestros resultados sugieren que, para promover los programas de control de Pinus radiata, deberían llevarse a cabo actividades en las zonas afectadas por mega incendios, dirigidas a personas jóvenes y a mujeres. Estos talleres deberían abordar los beneficios e impactos negativos de la especie en el ecosistema y el bienestar humano, su uso como combustible, material de construcción y recreativo, y las responsabilidades personales, estatales y empresariales asociadas a su gestión.
Convivencia de discursos respecto a apropiación de la naturaleza y procesos de comunalización, en relación a la gobernanza del ecosistema Laguna Junquillar.
Authors:   , SANTIBÁÑEZ RODRÍGUEZ FRANCISCA ANDREA
Published: November 2024

Laguna Junquillar es un ecosistema periurbano ubicado al sur de la comuna de San Pedro de la Paz. Forma parte de los lagos Nahuelbutanos y, dada su ubicación, es un ecosistema sometido a distintas presiones antrópicas. A pesar de ello, se reconoce un fuerte vínculo de distintos grupos con este lugar, sobre todo, como un espacio de reconexión con la naturaleza. Esta relativa dicotomía expresa la diversidad de relaciones que se pueden establecer con Laguna Junquillar y el proceso de comunalización que está atravesando, reconociéndose la urgencia de su gobernanza. Para el abordaje de lo problematizado se recurrió a distintos campos teóricos. Se recurrió a desarrollos teóricos relacionados a apropiación de la naturaleza, discurso, ambientalismos, comunes, procesos de comunalización y (co) diseño de gobernanza. Gracias a esta construcción teórica la investigación logró analizar la convivencia de discursos respecto a la apropiación de la naturaleza y procesos de comunalización, en relación a la gobernanza del ecosistema Laguna Junquillar. Para lograr dicho objetivo, el diseño metodológico se enfocó desde la investigación acción participativa, ya que facilita la interacción y reciprocidad durante su desarrollo. Su alcance fue propositivo y la muestra se diseñó en base a los actores que se movilizan en torno a Laguna Junquillar con énfasis en la subcuenca, realizando entrevistas semiestructuradas y un encuentro participativo. Otra cuestión relevante, son las consideraciones éticas que se tuvieron, con el fin de transparentar el desarrollo de la investigación. Respecto a los resultados, destacan como la relación con este ecosistema configura geometrías de poder entre los actores movilizados. Además, se identifica la presencia de distintos discursos expresados en ambientalismos, destacando el hallazgo del ambientalismo de desastre y el ambientalismo pedagógico. Por otra parte, respecto al proceso de comunalización, se reconoce la vulnerabilidad socioecológica en la que se encuentra y las oportunidades presentes en la acción colectiva para avanzar en su gobernanza. Respecto a esto último, se proponen áreas de gobernanza factibles, con figuras de participación claras y la necesidad de desarrollar un plan que identifique áreas de trabajo para realizar lo comunal.
Relación entre la autocompasión, desregulación emocional y mindfulness en adolescentes con diabetes tipo 1.
Authors:   , STUARDO ÁLVAREZ MARCIA
Published: November 2024

La diabetes tipo 1(DM1) en un problema a nivel mundial que genera un impacto psicoemocional importante en quien es diagnosticado. El objetivo es establecer la relación entre la autocompasión, el mindfulness disposicional y la regulación emocional en un total de 27 adolescentes entre 12 a 17 años diagnosticados con diabetes tipo 1. Estudio de tipo correlacional, descriptivo y de corte transversal, con muestreo no probabilístico por conveniencia. Se realizó la prueba linguística de la Escala de Autocompasión para Diabetes SCS-D, aplicándose junto a las Escala de Dificultades en la Desregulación Emocional (DERS-E), Mindful Attention Awareness Scale – Adolescents (MAAS-A) y la Escala de Preferencias de Control (CPS). Se encontraron diferencias de género en cuanto al nivel de autocompasión entre hombres y mujeres (U=129.000; p= .01), en la escala de desregulación emocional (U=35.500; p= .02), los hombres presentaron mejores puntajes en ambas escalas. En cuanto a los perfiles de adherencia, el colaborativo fue el predominante en los adolescentes, en cuanto a género, se observó el estilo colaborativo como predominante en los hombres, mientras que en las mujeres predominaron el estilo colaborativo y pasivo. No se encontraron diferencias significativas por género. Se encontró una asociación positiva entre desregulación emocional y buena adherencia (U=15.000; p= .01) según su hemoglobina glicosilada. Existen una relación positiva entre autocompasión y mindfulness disposicional (rho= .39; p=.04), mientras que se da una relación negativa entre autocompasión y la desregulación emocional (rho= -.51; p=.007); y entre el mindfulness disposicional y la desregulación emocional (rho= -.46; p=.02). En el modelo de regresión múltiple mostró que un 69% de la desregulación emocional puede ser explicada en función de las variables de mindfulness disposicional y sexo femenino.
En conclusión, existe una relación entre las variables de autocompasión, mindfulness disposicional y desregulación emocional en adolescentes con diabetes tipo 1. Esto abre una línea de investigación para que se continúe estudiando la relación entre estas variables.
Experimental confirmation of the bactericidal action of the domestic antiseptic “Anolit” in surgical practice
Authors: Styazhkina S. N. , Kuklin D. N. , Tikhonova V. V. , Gushchin S. G. , Bazhina Y. S. , Gaynetdinova I. I. , Tulynin S. B.
Published: November 2024

Background. Antimicrobial resistance is one of the most serious threats to modern clinical medicine. Despite the significant successes of modern pharmacology, the search for effective antiseptics that can influence wound processes continues. In our study, an experimental study of the effect of Anolit solution on pathogenic microorganisms Pseudomonas aeruginosa and Proteus mirabilis was conducted.The aim. To evaluate the antimicrobial activity of the domestic antiseptic “Anolit” against gram-negative pathogens of nosocomial infections using the example of P. aeruginosa and P. mirabilis.Methods. To assess the quality of the effect of “Anolit” on the studied colonies of microorganisms, experimental studies were performed in vitro. The bacteriological study was carried out in three stages using the Koch method.Results. “Anolit” is a modern antiseptic agent with a pronounced antimicrobial effect based on the electrolysis of aqueous solutions. Its ability to lyse pathogenic microorganisms (P. aeruginosa and P. mirabilis) has been confirmed by experimental research.Conclusion. The bactericidal effect of “Anolit” on the growth of gram-negative bacteria is shown, proving its high antimicrobial efficacy.
Metabolic syndrome associated with hyperandrogenism in the reproductive age. Hormonal profile in different ethnicities women
Authors: Darenskaya M. A. , Belenkaia L. V. , Kolesnikov S. I. , Sholokhov L. F. , Danusevich I. N. , Lazareva L. M. , Nadeliaeva Ia. G. , Kolesnikova L. I.
Published: November 2024

Background. Metabolic syndrome (MS) with hyperandrogenism comorbidity in women is considered a common concept; however, the contribution of the neuroendocrine regulation system indicators to this in reproductive age remains unclear.The aim. To analyze the activity of neuroendocrine regulation system in women of reproductive age of different ethnic groups with metabolic syndrome associated with hyperandrogenism.Materials and methods. The groups of women with MS of Russian (n = 209) and Buryat (n = 84) ethnic groups and a group of women with MS and polycystic ovary syndrome (PCOS) of Russian (n = 23) and Buryat (n = 10) ethnic groups were formed.Results. In women of reproductive age of the Russian ethnic group with MS and PCOS the study noted higher levels of anti-Müllerian hormone (AMH) (p = 0.030), testosterone (Ts) (p = 0.026), free androgen index (FAI) (p < 0.0001), dehydroepiandrosterone sulfate (DHEA-S) (p < 0.0001), and reduced levels of sex hormone-binding globulin (SHBG) (p < 0.0001) in relation to the control; in relation to the group with MS, we discovered increased values of AMH (p < 0.001), Ts (p = 0.030), FAI (p < 0.001), DHEA-S (p < 0.0001), and decreased values of SHBG (p = 0.001). In women of the Buryat ethnic group with MS and PCOS the study recorded increased values of AMH (p = 0.045), Ts (p = 0.002), FAI (p < 0.0001), DHEA-S (p = 0.033), decreased SHBG (p = 0.016) and 17-OH-progesterone (p = 0.027) levels in comparison with the control; in comparison with the group with MS we noted a higher level of DHEA-S (p = 0.006) and a decreased level of SHBG (p = 0.028).Conclusion. Women with metabolic syndrome associated with hyperandrogenism showed more intense changes in the neuroendocrine regulation system relative to control values regardless of ethnicity. In Russian women, the combined syndrome (MS with PCOS) was accompanied by a greater number of hormonal changes compared to the monosyndrome (MS) than in Buryat women. The data obtained indicate the need to assess and control the content of these metabolites in women with MS and PCOS, taking into account ethnicity.
Current epidemiological characteristics of cervical cancer in the Russian Federation
Authors: Kuleshova O. B. , Domonova E. A. , Akimkin V. G.
Published: November 2024

Background. The prevalence of cervical cancer (Cca) in Russian women makes it crucial to study modern epidemiological characteristics and adjust control measures accordingly.The aim. To analyze trends in the incidence of cervical cancer in the Russian Federation.Materials and methods. A retrospective epidemiological study was conducted on cervical cancer incidence in Russian Federation from 2008 to 2021. The materials of annual statistical data “Malignant neoplasms in Russia (morbidity and mortality)” and “Status of oncological assistance to the population of Russia” (2008–2022), data of the federal statistical reporting form No. 5 “Information about preventive vaccinations” (2021), data on the number of studies conducted (cytological study and HPV-test based on RT-PCR) in the clinical diagnostic laboratory of Central Research Institute of Epidemiology of Rospotrebnadzor (2013–2021) were used.Results and discussion. The trends of Cca incidence varied depending on the women’s age. Starting in 2016, there was a stabilization of the level of morbidity in women aged 30–49 with the subsequent decrease from 2019 due to the strengthening of secondary prevention measures, including the active introduction of HPV-test into the diagnostic schemes conducted in the Russian Federation. Increased control of cervical cancer caused a rise in the proportion of cases diagnosed at an early stage (carcinomas in situ and I–II stages Cca), the increase of detection rate of in situ carcinomas per 100 cases of Cca, the growth of the proportion of carcinomas in situ to I–II stages Cca, rise of the percentage of the cases detected actively, decrease of the number of Cca cases detected at later stages and one-year mortality index.Conclusion. The epidemiological analysis of cervical cancer incidence shows that preventive measures are effective and that there is a need to intensify and increase their coverage.
Indicators of oxidative stress and tissue hypoxia in various phases of Graves’ orbitopathy activity
Authors: Taskina E. S. , Kharintseva S. V. , Karavaeva T. M.
Published: November 2024

Graves’ orbitopathy (GO) is an extrathyroid complication of thyroid dysfunction characterized by chronic autoimmune inflammation of soft retrobulbar tissues. The data on the role of oxidative and hypoxic stress in GO are heterogeneous, which necessitates further research.The aim of the study. To evaluate the indicators of oxidative stress and tissue hypoxia at various phases of Graves’ orbitopathy activity.Material and methods. Examination of patients with GO (n = 32), with autoimmune thyroid pathology (n = 18) and healthy individuals (n = 15) was performed. The study included ophthalmological examination and blood sampling to determine the concentration of antibodies to the thyroid-stimulating hormone receptor, interleukin 17A (IL-17A), hypoxia inducible factor 1a (HIF-1a), TBK-active products and calculation of total antioxidant activity.Results. An increase in the concentration of TBK-active products in the clinical group was revealed compared with the control (p < 0.001). The total antioxidant activity was reduced at all phases of GO activity than in the control (p < 0.001). The level of HIF-1α did not differ in the study groups (H = 3.29; p = 0.51). Direct moderate correlations were found between the concentration of IL-17A and the level of TBA-active substances (p = 0.001), as well as inverse moderate correlations with the value of total antioxidant activity (p = 0.007). The activity of GO had weak correlations with total antioxidant activity (p < 0.001). Significant correlations between indicators of oxidative stress and tissue hypoxia were not found.Conclusion. In GO, regardless of the activity phase, there is an imbalance between the parameters of the “lipid peroxidation – antioxidant protection” system, which is manifested by an increase in TBA-active substances while reducing the total antioxidant activity. The indicators of tissue hypoxia did not differ in the study groups. The revealed correlations between the autoimmune inflammation activity in the orbit and oxidative stress emphasize the pathogenetic conditionality of the antioxidant drugs appointment in the therapy of GO.
Cloning of the Thermus thermophilus methionine aminopeptidase gene and confirmation of the enzyme functional activity
Authors: Bykov V. V. , Vologzhannikova A. A. , Trunilina M. V. , Kudryashov T. A. , Sokolov A. S. , Lapteva Yu. S.
Published: November 2024

Background. Methionine aminopeptidases (MAPs) are a class of enzymes that catalyze the removal of the N-terminal initiator methionine from a polypeptide chain. Bacterial MAPs are considered as targets for the development of broad-spectrum antibacterial drugs, and using MAPs in biotechnology necessitates the search for new MAPs and the study of their functioning and inhibition mechanisms.The aim of the study. To identify methionine aminopeptidase in the Thermus thermophilus genome (Tt-MAP) and to confirm its functional activity.Materials and methods. To identify Tt-MAP, we analyzed the Thermus thermophilus genome in the GeneBank database. Modern genetic engineering techniques (polymerase chain reaction, restriction, transformation, heterologous expression) were used to clone the putative open reading frame (ORF) encoding Tt-MAP in the pHUE vector. Various chromatography techniques (affinity, ion exchange, and size-exclusion) were used to obtain a purified enzyme preparation. The fluorogenic substrate L-methionine 7-amino-4-methylcoumarin (Met-AMC) was used to confirm the specific functional aminopeptidase activity of the enzyme.Results. An ORF encoding MAP was identified in the Thermus thermophilus bacterium genome. Oligonucleotide primers were designed based on the nucleotide sequence. The ORF was cloned in the vector, and the recombinant enzyme was produced in E. coli cells. A method for purifying the enzyme to a homogeneous state was developed using a series of sequential chromatographies, allowing up to 30 mg to be obtained from 1 liter of culture. Using the fluorogenic substrate Met-AMC, the specific functional activity of the enzyme was demonstrated (the enzyme cleaves methionine from the substrate).Conclusion. We have identified the Thermus thermophilus MAP and tested its functional activity. It has been shown that the ORF product TTHA1670 encodes a methionine-specific aminopeptidase, i. e. methionine aminopeptidase. The enzyme can be used in various fields of biotechnology and scientific research.
MEREC, Veri Zarflama Analizi ve EATWIOS Yöntemlerinin Hibrit Kullanımı ile Afrika Ülkelerinin Lojistik Performanslarının Değerlendirilmesi
Authors: Güçlü Pembe , Oudoum Mohamed Mohamed
Published: November 2024

Bu çalışmanın amacı, Afrika ülkelerinin lojistik etkinliklerinin Veri Zarflama Analizi (VZA), EATWIOS ve MEREC yöntemleri ile çok kriterli olarak değerlendirilmesidir. Ülkelerin etkinliklerinin analizi için literatür incelemesine dayalı olarak dört girdi (lojistik altyapı, konteyner liman trafiği, gümrükleme sürecinin verimliliği, uluslararası gönderi maliyetleri) ve beş çıktı değişkeni (gayri safi yurtiçi hasıla (GSYH), karbondioksit (CO2) emisyonu, zamanındalık, izleme ve takip, lojistik hizmetlerin yetkinliği ve kalitesi) belirlenmiştir. Elli dört Afrika ülkesi arasından, belirlenen girdi çıktı değişkenlerinde tam veriye sahip olan 18 ülke değerlendirmeye alınmıştır. Bu bağlamda, Afrika ülkelerinin lojistik performanslarına göre sıralamaları önce kriter ağırlıkları eşit varsayılarak daha sonra da kriterler MEREC yöntemi ile ağırlıklandırılarak boşluk tabanlı VZA ve EATWIOS hibrit yöntemi kullanılarak elde edilmiştir. MEREC analizi sonucunda lojistik performansının değerlendirilmesinde en önemli girdi değişkenlerinin konteyner liman trafiği skoru ile lojistik alt yapı olanaklarının olduğu; en önemli çıktı değişkenlerinin ise GSYİH ülke payı ve ulaşım ve lojistik kaynaklı CO2 emisyonu olduğu bulgulanmıştır. Nihai analiz sonuçlarına göre performansı en yüksek ülkenin Demokratik Kongo Cumhuriyeti, en düşük ülkenin Benin olduğu tespit edilmiştir.
Role of immunomodulation in childhood asthma and pediatrics: A case series
Authors: Andrew Kiboneka  , RonnieMwesigwa
Published: November 2024

The definition of immunomodulation refers to the action undertaken by the medication on autoregulating processes that steer the immunological defense system. Immunomodulation is modulation (regulatory adjustment) of the immune system. It has natural and human-induced forms, and thus the word can refer to the following:
· Homeostasis in the immune system, whereby the system self-regulates to adjust immune responses to adaptive rather than maladaptive levels (using regulatory T cells, cell signaling molecules, and so forth)
· Immunomodulation as part of immunotherapy, in which immune responses are induced, amplified, attenuated, or prevented according to therapeutic goals
Skrining Penyakit Tidak Menular di Desa Hutumuri, Ambon
Authors: Hutagalung Ingrid , Seipalla Gillian Elvira Belinda , Latuconsina Vina Zakiah , Latief Rahmi Rifany , Tiro Steven Rifany , Pattiasina Firensca , Rapa Yunita
Published: November 2024

Non-communicable diseases (NCDs) have a long duration and generally develop slowly.  In 2016, about 71% of the world's causes of death were NCDs, killing 36 million people per year. WHO data in 2018 states that 73% of deaths are currently caused by non-communicable diseases, 35% of which are due to heart and blood vessel diseases, 12% by cancer, 6% by chronic respiratory diseases, 6% by diabetes, and 15% by other NCDs. Community Service activities were carried out to screen NCDs in the Ambon City community, especially in Hutumuri Village, precisely at the Hutumuri Village Health Center, South Leitumur sub-district, Ambon City. The activities were blood glucose, cholesterol, and uric acid checks. Screening were carried out on 90 participants, and the examination results showed that 81% of participants had normal blood glucose levels. The cholesterol examination found that most experienced an increase in cholesterol from the expected levels (64.4%). Furthermore, for the uric acid examination, it was also found that most experienced an increase from the normal levels (72%). This community service initiative underscores the critical importance of early detection and intervention in managing NCDs, thereby contributing valuable insights into the prevalence of these conditions within specific demographic locales. Such endeavours are pivotal in shaping public health strategies and facilitating the allocating of healthcare resources towards mitigating NCDs' impact on global health.
Keamanan Dan Keselamatan Kerja (K3) Di Laboratorium IPA Pada SMP Negeri 7 SATAP
Authors: Lapu Petrus , Riupassa Pieter Agusthinus , Pesik Anneke , Kaihena Martha , Patty Kristi Lenci , Hiariej Adriana
Published: November 2024

Keamanan dan keselamatan kerja (K3) Laboratorium adalah semua upaya untuk menjamin keselamatan dan kesehatan pekerja laboratorium dari risiko-risiko yang ada di laboratorium. Kecelakaan di laboratorium dapat terjadi akibat kurangnya pengawasan, pengguna laboratorium kurang memahami bahaya dan cara menanganinya ketika terjadi kecelakaan yang dapat berdampak fatal bagi praktikan dan lingkungan sekitarnya. Kegiatan pengabdian kepada masyarakat kepada guru dan siswa SMP Negeri 7 SATAP Leihitu berupa sosialisasi pentingnya keaemanan dan keselamatan kerja (K3) di laboratorium dengan tujuan untuk meningkatkan pemahaman tentang pentingnya K3 di laboratorium sehingga dapat meminimalkan kecelakaan yang terjadi di laboratorium.
Pemberdayaan Ekonomi Kelompok Tani Tunas Baru Desa Sejahtra Astra Dusun Telaga Kodok Desa Hitu Lama, Maluku Tengah
Authors: Muspida Muspida , Ega L , Ferdinandus Stenly J , Christianty Restia , Wenno Meiske , Faisal Muhammad , Sinay Lexy Janzen , Borel Aryanto , Regar Erfendi , Arifin Hasmia Melati , Souhoka Semuel
Published: November 2024

Agricultural development, as a component of national development, has an important role in the recovery of the national economy. This strategic function focuses on increasing regional income, providing food and industrial raw materials, increasing exports and foreign exchange, creating jobs and business opportunities, increasing farmers' income, and improving community welfare. One of the challenges farmers face is a lack of negotiating power. Consolidating farmers into one forum can strengthen negotiating power and integrate economic movements from pre-production to marketing. The activities carried out also experienced several business obstacles experienced by the business group, including climate and weather and Hurricane Lanina, which hit the Central Maluku region and its surroundings, causing disruption to organic vegetable production. DSA Telaga Kodok does not yet have a post-harvest packaging house, so it is difficult to obtain organic certification. The organic certificate has expired, so currently, farmer market partners have not received vegetables from DSA Telaga Kodok.
Validity and Reliability of Mathematical Reasoning Ability Instruments in High Schools with Winsteps
Authors: Syahwa Keysha Alifia , Gustia Satria Kamal , Faradillah Ayu , Ulfah Syafika
Published: November 2024

The mathematical reasoning ability in understanding mathematical material in high school students still has not touched perfect scores. A valid and reliable instrument is needed in measuring mathematical reasoning skills in students. Validity and reliability testing of the instrument is carried out to ensure whether an instrument can be used to provide accurate results in a measurement being performed. Therefore, this study aims to determine the level of validity and reliability of mathematical reasoning skills in students using Winsteps. The method used in this study is a quantitative survey method, with 252 respondents in high schools in Jakarta. This study uses 3 indicators that are a reference in measuring the mathematical reasoning ability possessed by students. The validity test on the instrument shows that all items on the instrument are valid because they meet the criteria of MNSQ, ZSTD, and Pt Mean Corr except for item 1 which has a ZSTD value of > 2.0 and item 3 has a ZSTD value of < -2.0. Meanwhile, the reliability test obtained an Alpha Cronbach calculation of 0.74 which means that the value of the reliability item is high so that the instrument is declared reliable for use. The DIF analysis using winsteps shows that all question items used in the instrument are valid because none of the question items contain bias referring to the DIF Analysis criteria, namely the DIF Contrast value > 0.5 and the probability value < 0.05 where all the value of the question items actually obtained a DIF Contrast value of < 0.5 and a probability value > 0.05.
Application of Max-Plus Algebra for Time Optimization of Wooden Furniture Production System “Berkah Usaha” Jepara Regency
Authors: Khulda Ifrikhatul , Isnarto Isnarto
Published: November 2024

This research aims to provide a periodic schedule on the Berkah Usaha wood furniture production system in Jepara using Max-Plus Algebra. The data required in the research is data on the flow and processing time of each project work unit. In this research, the main focuses on the Berkah Usaha wooden furniture dining table production system whose processing stages consist of raw material preparation, measurement, wood cutting, wood smoothing, measurement of puruses and holes, table floor manufacturing, puruses and holes manufacturing, table floor smoothing, assembling, sanding, and finishing. The techniques of data collection used in this research are interviews and field observations. Then, a directed graph and model of the Berkah Usaha wood furniture production system were compiled based on the flow data, processing time for each project work unit, and the rules for applying Max-Plus Algebra to the scheduling system. Analysis of the Max-Plus Algebra model of the Berkah Usaha wooden furniture production system using the Power Algorithm with Scilab software assisted. The results of the analysis obtained the production time period of the Berkah Usaha wooden furniture for 253 minutes and the optimal time to start production on each processing unit are 0, 11, 46, 92, 115, 117, 127, 137, 155, 195, 223 time units (in minutes).
Penggunaan Konteks Budaya Ramayana Ballet Prambanan Untuk Soal Literasi Matematika Bagi Siswa SMP
Authors: Gunawan Monica Tiara , Julie Hongki , Ruditho M. Andy
Published: November 2024

The purpose of this research is to develop and classify mathematical literacy questions using the context of Ramayana Ballet Prambanan Ballet for junior high school students. The type of research used is design research. The data collection methods used were observation, test, and interview. The instrument validation process used by researchers is expert validation and the technique used to test data validity is triangulation technique. The data analysis process used was reducing data, presenting data, and drawing conclusions. The results obtained were from the context of the Ramayana Ballet Prambanan Ballet could be made eight questions in the domain of numbers, data and probability analysis, algebra, measurement, and geometry for cognitive levels (1) knowing with a counting indicator, (2) applying with interpreting, applying/executing indicators, and (3) reasoning with a making justification indicator.
Insights on Psychedelics: A Systematic Review of Therapeutic Effects
Authors: Kugel Joshua Maurice , Laukkonen Ruben Eero , Yaden David Bryce , Yucel Murat , Liknaitzky Paul
Published: November 2024

Insights are a common and powerful subjective experience that frequently occur during psychedelic experiences, and are often considered by clinicians and patients to be central to the therapeutic value of psychedelics, but this has not been systematically assessed. Insight refers to a sudden acquisition of knowledge or understanding that is strongly felt to be true or real. In this systematic review, we analysed data from 98 studies reporting insight following a psychoactive dose of a classic-psychedelic, to elucidate several aspects of psychedelic-catalysed insight (PCI), including its prevalence, relationship to dose, time-course, and relationship to therapeutic outcomes in the context of mental health and wellbeing. Experiences of PCI were positively correlated with dose, and reached statistical significance in 43 of 46 (93%) studies that compared psychedelic and placebo conditions. Crucially, 25 of 29 studies (86%) found that PCI was associated with positive therapeutic outcomes, and this relationship was often stronger than mystical-type experiences, which have received more research attention. This systematic review contributes to our understanding of the aspects of subjective experiences that drive psychedelic-related outcomes, and suggests that PCI is an important topic for the clinical practice of psychedelic therapies and for understanding the mechanisms of psychedelic therapy more broadly.
Measuring Social Ties from Roll Call Votes: A Fused Latent Factor and Social Network Approach
Authors: Lee Hane , Davison Andrew , Ying Zhiliang
Published: November 2024

Congressional literature suggests that the motivations behind roll call votes are complex, spanning the legislator's ideology, party strategies, and social influences. In terms of methodology, latent factor models have dominated roll call analysis, where the estimated "ideal points" are interpreted as the legislators' partisan-ideological positions, but these models do not account for partisan or social motivations behind the votes. On the other hand, some researchers have explored the social influence behind these votes using network models, but this approach often overlooks the role of ideology or parties. We address this gap by integrating the partisan-ideological and social approaches through a fused latent factor and social network model. This model decomposes the effects of partisan-ideology and social connections on roll call votes while giving priority to the former. Additionally, our method provides a direct measurement of social ties from roll call votes, rather than relying on proxies such as cosponsorship to first estimate the social effect and later make connections to political outcomes. We apply our model to the 101st Senate and find that the model successfully decomposes ideology and partisanship from social ties. The estimated social network captures notable friendships and geographical communities. We also demonstrate that cosponsorship and shared committee membership, commonly viewed as indicators of social connections, are either closely aligned with the legislator's revealed partisan-ideological preferences or have minimal legislative impact.
The Power of Developmental Thinking: Social-Cognitive Complexity of Urban Secondary Teachers’ Pedagogical Narratives Predicts the Quality of Their Classroom Practices
Authors: Kundrak Christina , Immordino-Yang Mary Helen , Candaux Emily , Knecht Douglas , Garrett Jeffrey
Published: November 2024

Adolescents undergo critical neuropsychological development, but this rarely meaningfully informs pedagogy. Do teachers with developmentally informed perspectives enact higher quality practices? We interviewed 40 public secondary teachers from schools serving low-SES urban communities, nominated for excellence by their administrators, about their teaching practices. Four characteristic “pedagogical narratives” emerged from qualitative analysis and were ordered by the social-cognitive complexity with which teachers integrated discussions of students’ personal and intellectual development. An independent team rated participants’ teaching. The complexity of participants’ narratives statistically predicted the quality of their teaching practices, suggesting that how teachers understand the coordinated nature of adolescents’ academic learning and personal development relates to how effectively they teach—an important finding for reforming secondary education and educator preparation.
Spatial funding frameworks in the UK since 2010
Authors: MacKinnon Danny , Haisell Eleanor , Pike Andy , Vethuis Sanne , Tomaney John
Published: November 2024

Over the past fifteen years, a succession of funding programmes have been establishedto address spatial inequality in the UK. This encapsulates the problem of policy churn andreinvention as new programmes often have very similar objectives to their predecessors.Aggregate funding levels over the 2010-33 period are substantial, but short-termist andinadequate to the scale of the problem.
The Interrelationship between English Language, Christianity, and Colonization: The gift of the Second Babylon
Authors: GOLBAN VARVARA
Published: November 2024

The English language has evolved significantly, expanding from the British Isles to become aglobal lingua franca, largely due to colonization and Christianity. Christianity's reliance onlanguage facilitated its spread, as translations of the Bible into various vernaculars broke downcultural and linguistic barriers. Colonization often suppressed indigenous languages, imposingdominant languages for economic development and religious conversion. This resulted inlinguistic imperialism, where the colonizers' language furthered the spread of Christianity.Additionally, interactions between indigenous peoples and colonizers led to linguistic hybridity,shaping local languages and cultures. Understanding the historical trajectories of the Englishlanguage reveals how colonization and Christianity influenced its rise, highlighting the need for abalanced approach to language policy and cultural identity that respects both global and locallinguistic heritage.
Online Tools to Promote Sustainable Behaviours: A Content Analysis
Authors: Woodhouse Sarah , Doughty Faye , Rodrigues Angela
Published: November 2024

Objective: Immediate and drastic action is required to combat the urgent issue of climate change. Engaging in sustainability behaviours, such as using public transport and eating less meat, can help towards saving the environment. Due to the accessibility and widespread use of the internet, online sustainability tools (websites) may be a scalable and affordable way to promote behaviour change. Therefore, the aim of this study was to find, describe, and assess a range of online tools that aim to encourage sustainable behaviours. Methods: The online sustainability tools were identified by means of systematic searches on Google, as well as from the existing literature. Those that were included in this study were reviewed and coded based on Behaviour Change Techniques (BCT) Taxonomy (v1) and the principles of Persuasive Systems Design (PSD). The Health-Related Website Evaluation Form (HRWEF) was also used to assess the quality of the online tools, and readability scores were generated. Results: The 11 websites included in the final analysis mapped onto a total of 22 BCTs. Of these, the most frequently identified were ‘5.3: Information about social and environmental consequences’ (100%, 11/11), ‘4.1: Instruction on how to perform a behaviour’ (81.82%, 9/11), and ‘9.1: Credible source’ (72.73%, 8/11). 19 PSD principles overall were identified in the included websites, with ‘ClimateHero’, Get Greener’ and ‘WWF Footprint Calculator’ displaying the most (n=14 PSD principles), and all of the websites were categorised as being of either ‘excellent’ or ‘adequate’ quality. Conclusion: This study helped identify the commonly used BCTs and PSD principles in online sustainability tools. ‘ClimateHero’, ‘Get Greener’, and ‘WWF Footprint Calculator’ were identified as the top 3 websites. Using this coding and the subsequent results of the quality analysis, recommendations to improve future online interventions have been made in order to increase engagement.
Comparing Discriminatory Behavior Against AI and Humans
Authors: Zhuang Mike , Turel Ofir , Deschrijver Eliane , Ramsey Richard
Published: November 2024

Although discrimination is typically believed to occur from well-defined categories like ethnicity, disability, and sex, studies have found that discrimination persists in minimal conditions lacking such categories. Participants have been found to preferentially allocate resources based on seemingly arbitrary shared characteristics such as dot estimation choices. Here, we use a preregistered experiment (n = 500) to investigate whether humans discriminate in a similar manner when interacting with artificial intelligence (AI) agents that ostensibly made dot estimations. We hypothesized that because humans harbor prejudice against algorithms relative to other humans (otherwise known as algorithm aversion), the strength of discriminatory behavior may be greater against AI than humans. Surprisingly, we found that participants distributed resources in a similar manner, albeit unequally, to both human and AI agents. Specifically, participants favored the other agent when decisions were aligned. Our findings suggest that discriminatory behavior is less influenced by the recipient’s identity and more shaped by choice congruency.
Adaptive Neural Contextualization for Expansive Knowledge Representation
Authors: Canus Samuel , Torrington William , Northfield Mia , Weatherstone Charlotte
Published: November 2024

Adaptive approaches to context modeling have emerged as critical mechanisms for addressing the limitations of static representation techniques, particularly in tasks requiring complex understanding of linguistic dependencies. The proposed framework introduces a dynamic contextualization mechanism that enhances the representational capabilities of transformer-based architectures through iterative refinement of context-sensitive embeddings. Quantitative evaluations demonstrated significant improvements in accuracy, contextual coherence, and perplexity reduction across multiple linguistic benchmarks, establishing the robustness of the approach under diverse input conditions. Qualitative assessments highlighted the framework's ability to maintain semantic alignment in domain-specific tasks, particularly within highly specialized or noisy datasets. The methodology incorporated adaptive layers seamlessly into an open-source transformer model, enabling efficient long-sequence processing without imposing excessive computational demands. Cross-lingual evaluations further validated its capacity to generalize effectively across typologically diverse languages, highlighting its potential for multilingual applications. The integration of hierarchical attention mechanisms facilitated the capture of long-range dependencies, while cross-attention modules ensured precise alignment with task-specific queries. Results also demonstrated robust performance under adversarial scenarios, showcasing adaptability to unstructured and incomplete inputs. Memory utilization analyses revealed that the framework maintained scalability across large datasets, balancing computational efficiency with enhanced performance metrics. The proposed framework redefines the boundaries of contextual modeling through its ability to dynamically adjust representations, offering a scalable and efficient solution for diverse linguistic challenges. These findings establish Adaptive Neural Contextualization as a foundational innovation that addresses critical gaps in current methodologies while advancing the field of language modeling through its dynamic adaptability and efficiency.