bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Different Zn Concentrations on Crop Growth and Root Nodulation in Yard-Long Bean (Vigna unguiculata L.)
Authors: B.S.K.Bhagya  , Geretharan T. , Srikrishnah S.
Published: November 2024

An experiment was conducted to study the effect of Zinc (Zn) as a micronutrient on growth and nodulation in Vigna unguiculata L. The experiment was carried out as a pot experiment in the Crop Farm, Faculty of Agriculture, Palachcholai, Eastern University, Sri Lanka from August to November 2023. The experiment was laid out in Complete Randomized Design with six treatments and four replicates. The treatments are T1 (Control), T2 (50 mg ZnSO4/kg soil), T3 (100 mg ZnSO4/kg soil), T4 (150 mg ZnSO4/kg soil), T5 (200 mg ZnSO4/kg soil) & T6 (250 mg ZnSO4/kg soil). The experiment used source of Zinc in the form of Zinc Sulphate (ZnSO4,5H2O) which yard-long bean plants can grow. The experiment results showed that, T2 treatment, the soil treated with 50 mg ZnSO4/kg soil significantly increase the Plant height, Chlorophyll content, Leaf area, Fresh weight of shoot & root, Dry weight of shoot & root, Number of nodules, Effective nodule percentage, as well as Soil respiration compared to the other treatments. However, beyond the level of 200 mg ZnSO4/kg soil, reduces the growth & nodulation of Vigna unguiculata L. and this shows that the level 200 mg ZnSO4/kg soil and beyond that level were the toxic level to the Vigna unguiculata L. Accordingly, the treatment T2 (50 mg ZnSO4/kg soil) was at the micronutrient level of Zn concentration which involved in many key cellular functions and show the best positive effect on growth and nodulation in Vigna unguiculata L. The results clearly indicate that, Zn can be use as a micronutrient up to a trace level in inducing plant growth and nodulation. However, at higher levels of Zn may act as heavy metal and cause phyto-toxicity in plants.
Impact of Fruit Order on Cucurbits Yield Components: A Case of Lagenaria siceraria (Molina) Standl
Authors: KOMENAN Any Olivier , KOUAKOU Adjoua Dorcas , ANOMAN Tchimonbié Messikely , TOFANGUY Jean-Clément , KOFFI Kouamé Kévin
Published: November 2024

Lagenaria siceraria is a trendy plant in Ivory Coast for its seeds. However, production of this plant remains relatively low. One of the underlying reasons for poor yields is poor control of crop techniques. This study is part of the improvement of L. siceraria production. It was conducted on the experimental farm of Nangui Abrogoua University in Abidjan. The study focused on the effect of fruit order on agronomic parameters related to fruits and seeds. To this end, a series of experiments was conducted. Fruits formed on the same plant were classified into three groups: J0 for the first generation, J8 for the second and J15 for the third generation. The results obtained indicate that for all agronomic parameters, the weight of the fruit (PoFr), the volume of the fruit (VoFr), the volume of the seed lodge (VLGr), the number of seeds per fruit (NoGr), the weight of 100 seeds (P100), the highest values are obtained for fruits of the first generation of fruit (J0). Thus, the fruits that appear first have a better agronomic quality. Farmers should use seeds from first-generation fruits for planting.
Assessment of Plasma Levels of Calcium, Creatinine and Glucose among Hypertensive Patients in Edo State, Nigeria
Authors: Umeche Ijeoma Evangeline , Nwoka Nkiruka Chinenye , Osahenye Precious Chukwunonso , Obi Collins Uchechukwu , Ogueze Anthonia Chinenye
Published: November 2024

The present study needs to assess the plasma levels of calcium, creatinine and blood glucose among hypertensive patients in Edo State, Nigeria in order to ascertain whether plasma levels of these parameters are associated with hypertension in this population which will provide improved insight on proper management of hypertensive conditions. Several hereditary and lifestyle factors, including nutrition, influence blood pressure. In this regard, sodium is an important mineral that, in addition to its functions in fluid balance, action potential generation, digestive secretions, and nutrient absorption, also plays a key role in blood pressure regulation, with lower sodium intake linked to lower systolic and diastolic blood pressure. patients compared with their non-hypertensive counterparts. This could be as a result of an overactive parathyroid gland leading to excessive secretion of parathyroid hormone and the attendant increase in plasma calcium level. Regular screening for the plasma level of calcium, creatinine and blood glucose should be considered as routine tests for hypertensive patients. Adequate awareness of the risk of ignoring these parameters in hypertensive patients should be ensured.
Defluoridation of Groundwater Using Low-cost Adsorbents
Authors: Jothimani Palanisamy , Velu Sai Akshitha Singara , G Sabesh Vagul
Published: November 2024

Excessive fluoride in groundwater poses significant health risks to millions of people worldwide, necessitating effective and accessible defluoridation methods. This study investigates the use of column filtration for removing fluoride from groundwater. The study employs a systematic approach to evaluate the performance of different adsorbent materials in a fixed-bed column setup. Various materials were tested as adsorbents in column, including Brick powder, Neem leaf powder, Lime, Sawdust, and Vetiver. The research examines the effects of key operational parameters such as bed depth, flow rate, and initial fluoride concentration on the overall removal efficiency. Experiments were conducted using groundwater to assess the method's effectiveness. Results indicated that column filtration can effectively reduce fluoride concentrations to below the World Health Organization's recommended limit of 1.5 mg/L. This report contributes to the development of efficient, cost-effective, and sustainable solutions for groundwater defluoridation. All adsorbents used were inexpensive materials, available easily in nature and locally at village or rural level. Some of the adsorbents were very effective in removal of fluoride ion and can be used as defluoridating agents but they impart color and turbidity to the groundwater. Among all the adsorbents used, Vetiver demonstrated higher removal efficiency of 78% followed up by limestone 77% removal but hindered by its precipitation. Sawdust and brick powder were also efficient up to a certain extent of 72% and 69% respectively in adsorbing fluoride ions. Neem leaves powder was found to be least effective in adsorbing showing about 50% removal efficiency.
Bacteriology and Physicochemical Analysis of Borehole Water in Some Hostels of a Tertiary Institution in Port Harcourt, Nigeria
Authors: Sampson T. , Baranu B. S. , Ekiamene T. A. , Ikpokpo E.
Published: November 2024

Several factors influence the quality of water for human consumption. Most of these factors are more of anthropogenic origin than nature and thus exercises an untold health effect on the end-users of such water body. Bacteriology and Physicochemical Analysis of Borehole Water in Some Hostels of a Tertiary Institution in Port Harcourt, Nigeria. Water samples were collected from six (6) hostels for each study period, and subjected to standard laboratory procedures to analyze for parameters such as pH, nitrite, nitrate, dissolved oxygen (DO), electrical conductivity (EC), Phosphate, as well as standard procedures for antibiotics susceptibility and molecular characterization. Result of the physicochemical parameters showed that the parameters ranged from 5.26±3.53 mg/L to 7.61±0.01 mg/L forpH; 0.61±0.01 to 2.56±0.01 mg/L for Dissolved Oxygen (DO); 96±1.41 μS/cm to 503.5±0.71μS/cm for electrical conductivity; 4.56±0.03 mg/L to 20.3±0.01 mg/L for nitrate; 0.003±0mg/L to 0.03±0mg/L for nitrite; 0.12±0mg/L to 0.17±0mg/L for phosphate. Statistical evaluation showed there was a significant difference (p < 0.05) between the mean values of physicochemical parameters studied, except for pH that recorded no statistical difference (p > 0.05). From the study, 5.6% of Staphylococcus species were resistant to Pefloxacin and Rocephin, while 5.9% of Bacillus species were resistant to Ampiclox. Similarly, 3.33% of Salmonella species were resistant to Augmentin, while the rest of the gram negative isolates were either susceptible or within an intermediate range of susceptibility to the antibiotics tested. Molecular characterization of some bacterial species isolated had pairwise identity with Klebsiella pneumonia strain CP27 and Escherichia coli strain RIZHAO 498.1, Staphylococcus haemolyticus strain SH1. The study has shown that the physicochemical water quality variables were all within the WHO limits, with bacterial species having high percentage susceptibility to the antibiotics tested. Regular water quality monitoring is however recommended to ensure continuous access to water of good quality in hostels within the university community.
Vetiver [Chrysopogon zizanioides (L.) Roberty]: An Aromatic Root Crop for Soil and Water Conservation
Authors: Sharma Yashaswini
Published: November 2024

Khus grass or vetiver (Chrysopogon zizanioides (L.) Roberty) is a hardy perennial aromatic grass with long enormous tufted fibrous root system. Commercially, dry roots are used for extraction of essential oil that acts as a fixative in perfumery industry worldwide. Besides, vetiver roots are used in medicinal and pharmaceutical industries to treat rheumatism, arthritis, gouty joints, paralysis and indigestion. Roots and root oil have strong anti-oxidant, stimulant, carminative and cooling properties and used in Ayurvedic medicines. Traditionally, vetiver plants are being used to cultivate across hill slopes, waterways and wastelands to reduce runoff and soil conservation. During 1990’s World bank was promoting use of vetiver grass as contour vegetative barrier in upland farming systems of Asian and African countries. Further, recent studies report the use of vetiver in phytoremediation, reclamation of mined lands and soil and water detoxification in addition to carbon sequestration. Due to introduction of modern cultivation practices, traditional soil conservation practices are being vanished gradually over a period of time. In this regard, an attempt has been made to review the scientific evidence for use of vetiver grass as a soil and water conservation measure along with phytoremediation.
Assessing the Zinc, Boron and Rhizobium Inoculation on Yield and Economics of Kharif Mungbean (Vigna radiata L.)
Authors: Singh Ajai , Dubey Digvijay
Published: November 2024

The present experiment was carried out during kharif season of 2021 and 2022 at Instructional farm, Kamla Nehru Institute of Physical and Social Sciences Sultanpur, U.P. India. Four levels of zinc (0, 2.5, 5.0 and 7.5 Kg Zn ha-1), three levels of boron (0, 0.5 and 1.0 Kg B ha-1) and two levels of rhizobium i.e. Uninoculated (Control) and inoculated. A split-split plot design with three replications was used. Zinc levels were allocated to the main plots, boron levels in the sub-plot, while Rhizobium inoculation in the sub-sub plot. Results revealed that dry weight and seed and stover yield was observed that Rhizobium inoculation with application of zinc 7.5 kg ha-1 and Application of boron 1.0 kg ha-1. Obtaining seed yield from Rhizobium inoculation (8.53 and 8.71 q/ha-1) with application of zinc (8.53 and 8.79 q/ha-1) and Application of boron (8.45 and 8.70  q/ha-1). The highest net return (Rs. 58211.0 and 65488.50 ha-1) and benefit cost ratio (1.75 and 1.97) were obtained with 7.5kg Zn ha-1 + 1 kg B ha-1 + seed inoculation with rhizobium. It could be recommended for cultivation of mungbean.
Sustainable Management of Root-knot Nematodes in Tomatoes: Effects of Inoculum Levels under Polyhouse Conditions in Northeast India
Authors: Nongbri Euphema , H Jeevan. , Kadam Veronica , Patidar Raghubir Kumar , Dutta Pranab , Thakuria Dwipendra , Thangjam Rojeet
Published: November 2024

The study aims to evaluate the impact of different inoculum levels of root-knot nematodes (Meloidogyne spp.) on tomato plants under polyhouse conditions in Northeast India. The research provides early predictions of nematode infestation severity and guides farmers on sustainable management practices, including biological control, to keep nematode populations below the economic threshold. Soil samples from key tomato-growing areas in Nongpoh, East Khasi Hills, and West Jaintia Hills districts of Meghalaya were collected, and inoculum levels ranging from 500 to 8000 J2 were tested using completely randomized design. The study found a significant increase in root gall index, egg mass production, and nematode population with higher inoculum levels. Even low inoculum levels (500 J2) caused notable damage to the plants. These findings underscore the importance of managing nematode populations early to reduce crop losses and highlight the need for efficient, low-inoculum control strategies. This study contributes to the sustainable management of nematodes in agricultural practices.
Genetic Divergence Analysis for Quantitative Traits in Rice (Oryza sativa L.) Germplasm under Irrigated Conditions
Authors: Sneha Malikedi , Lal Gaibriyal M. , Bara Bineeta M. , Rasagnya Nagothu
Published: November 2024

The present study was with the aim of knowing genetic divergence analysis for quantitative traits among the rice genotypes for agronomical and yield traits. The experimental material consists of 36 rice genotypes sown in a Randomized Block Design with three replications and observations recorded on randomly selected five plants for 13 quantitative traits. The results indicated that the genotype Nagarjuna shows greater yield among the genotypes. The genetic parameters show high GCV and PCV in grain yield per plant, and according to D2 analysis, the 36 genotypes were grouped into 6 clusters based on Tocher's method of cluster formation. Cluster I is the largest cluster, consisting of 29 genotypes, while Cluster II has 3 genotypes. Cluster III, IV, V, and VI were the smallest, with only a single genotype. The maximum intra-cluster distance was found in cluster II (39.19), followed by cluster I (30.15), and the maximum inter-cluster distance was shown in between cluster VI and cluster II (178.97), followed by cluster VI and cluster V (151.75). Based on cluster means, Cluster III (39.67) shows greater among 6 clusters for grain yield per plant as contributing the highest among all the quantitative characters. Hence, these traits could be focused on for selection while improving seed yield and seed quality. On the basis of their greater inter-cluster distance, high value of cluster means, and performance of the individual germplasms for the character, the germplasm could be used in improving seed yield and seed quality programs for improvement of different plant characters of the rice.
Evaluation of the Suitability of Horticultural Crops under Prevailing Environmental Conditions - A Case Study of Punjab
Authors: Nagdev Ritu , Meena R.K. , Kumar Ashok , Joon Vikas , Surya Jaya N.
Published: November 2024

Alternate land use options such as horticultural crops help in ensuring efficient land resource utilization. Thus, it is essential to evaluate the agri-environmental conditions for economically viable and sustainable horticultural production. A study was carried out for land use planning of Rajpura block in Patiala district of Punjab. Under this study, soil-site suitability of horticultural crops were evaluated by considering key soil parameters such as texture, depth, slope, EC, pH, organic carbon content, erosion, drainage, and climate factors viz., rainfall and temperature, etc. The soils of the block were interpreted to assess their suitability for various horticultural crops viz., mango, grapes, banana, sapota, guava, pomegranate and citrus fruits. The mango cultivation was found suitable for almost 50% area and moderately suitable for 34% area. Soil-site suitability characteristics evaluation for grape cultivation revealed that around 34% area of the block is suitable while 50% area is moderately suitable. The banana and sapota crop cultivation was found to be highly suitable for approximately 45% area, whereas moderately suitable for 40% area. In context of guava and pomegranate, nearly 34% area was covered under suitable class and 50% area was covered under moderately suitable class, respectively. The citrus crops are highly suitable for this block which covers the maximum area of the block about 61% and moderately suitable for almost 23% area, respectively. The small fraction of the block, only 1.68% (476 ha) exhibits marginal suitability for the cultivation all fruit crops. The horticultural crop suitability maps were generated by using remote sensing and GIS tools. Hence, it can be concluded, the Rajpura block has vast dimensions for the horticultural farming which will lead to land resource management, sustainable land use planning and livelihood security of farmers of the block. This study will also help policy makers and stake holders for the horticultural developmental planning of this block.
A Cross-Sectional Study To Assess The Stress And Anxiety Of Antenatal Mothers On Pregnancy Induced NonCommunicable Diseases In A Selected Tertiary Care Hospital
Authors: C Ms. Kowsalya. , K Mrs. Vanitha.
Published: November 2024

Background: Pregnancy-induced Non communicable diseases (NCDs), also known as chronic diseases, are not passed from person to person. They are of long duration and generally slow progression in pregnant periods. The pregnancy-induced non communicable diseases are primarily anemia, thyroid disorders, gestational diabetes mellitus, and pregnancy-related hypertension. The main factor in global maternal mortality and morbidity in noncommunicable diseases. Maternal mortality is one of the health indicators that illustrates the burden of sickness and death. Each year, more than 150 million women become pregnant in developing countries, and an estimated 500, 000 of them die from pregnancy-related causes. Apart from health issues, the majority of women in underdeveloped nations die owing to a lack of access to maternity health care services. Aim: The present study aims to assess the stress and anxiety of antenatal mothers on pregnancy induced noncommunicable diseases in a selected tertiary care hospital. Methods: The study conducted with descriptive approach.134 antenatal mothers in their 28 to 38 weeks of gestation were selected tertiary care hospital by purposive sampling technique. The data were collected from the participant using self-administered questionnaire. The data analyzed using descriptive and inferential statistics. Results: The analysis revealed that distribution of pregnancy induced non communicable diseases among the participant were 43 had GDM,37 had PIH,14 had thyriodism,6 to have anemia. The majority 73%,58.9% of antenatal mother with pregnancy induced non communicable diseases had severe stress and anxiety respectively. There was a strong correlation between stress and anxiety with pregnancy induced non communicable diseases (r=0.67) Conclusions: The findings of this study suggest Early screening and intervention may have great significance for reducing mental disorders of pregnancy induced non communicable diseases antenatal women and in which further help us teach to antenatal mother’s pregnancy induced non communicable diseases and reducing stress and anxiety coping strategies
Inflamação, Exercício Aeróbico E Depressão: Uma Revisão Narrativa
Authors: Silva Katiely Santiago Da , Nascimento Graciella Sales , Silva Kerolayne Mendes Da , Maia Raquel Da Rocha Paiva , Bezerra Jader De Andrade
Published: November 2024

Introdução: a depressão, uma das principais causas de incapacidade no mundo todo, é caracterizada por sentimentos persistentes de tristeza, perda de interesse e alterações no apetite ou no sono. Embora a etiologia exata da depressão permaneça complexa, evidências crescentes sugerem que a inflamação crônica desempenha um papel significativo em sua patogênese. Objetivo: realizar uma revisão de literatura sobre a influência do exercício físico aeróbico na modulação da depressão, principalmente à associada a inflamação. Materiasi e métodos: trata-se de uma revisão de literatura narrativa de estudos publicados entre 2010 e 2024 em bases eletrônicas como PubMed, Google Acadêmico e Medline. Foram utilizados os descritores, exercício aeróbico; atividade física; inflamação e depressão em português e inglês. Resultados: as pesquisas demonstram uma forte ligação entre depressão e inflamação. O tratamento tradicional para depressão inclui farmacoterapia e psicoterapia, nem sempre respondem adequadamente ou causam efeitos colaterais adversos. O exercício aeróbico, como uma abordagem não farmacológica, é promissor no gerenciamento da depressão, modulando a resposta inflamatória, levando a reduções nas citocinas próinflamatórias, dessa forma, esse efeito anti-inflamatório pode contribuir para os benefícios antidepressivos. Conclusão: O exercício físico aeróbico como um tratamento multifacetado, principalmente o exercício de intensidade moderada, é capaz de modular tanto a saúde mental quanto a resposta inflamatória
Patient Perceived Quality Of Care And TheAssociated Factors For Selected InvasiveDiagnostic Procedures In Outpatient Departments
Authors: (N) Ancymol M.C, M.Sc , Ph.D Punitha Ezhilarasu,
Published: November 2024

Background: Continuous assessment is essential for delivering high-quality care, particularly in outpatient departments, which serve as the gateway to hospital services. It is crucial to evaluate the quality of care provided during diagnostic procedures in this setting. This study aims to assess patient-perceived quality of care and the associated factors for selected invasive diagnostic procedures in the outpatient department of CMC Vellore. Materials and Method: A descriptive cross-sectional study was conducted to evaluate patient-perceived quality of care in the Medical, Surgical, and Orthopaedic Departments of Christian Medical College. Using Total Enumerative Sampling Technique, 140 subjects were enrolled and assessed through a Patient Perception Scale and a checklist developed by the investigator. Results: More than half of the patients (55%) reported receiving high-quality care during their procedure, while 34.29% perceived moderate quality, and only 10.71% indicated low overall care quality. A statistically significant association was found between the type of procedure, doctor's gender, and the quality of care perceived by patients. Additionally, there was a negative correlation between perceived quality of care and waiting time (r = -0.211)
Effect of an Educational Training Program for Nurses Regarding Triage System Working Competency
Authors: Goda Abeer A. , Ali Zienab H. , Mahmoud Forat H.
Published: November 2024

Background: The term "triage" means sorting out. Medically, it's a process used to prioritize who needs emergency medical attention first, whether injured or sick people or disaster survivors. Aim: The current study aimed to evaluate the effect of an educational training program for nurses regarding Triage System working competency. Design: Quasi experimental research design was used in this study. Setting: The study was conducted at Ain-Shams Specialized Hospital. Subject: Consist of a convenience sample (50) of emergency nurses. Data collection: three tools were used in this study as 1st tool: Self-administered Questionnaire that consisted of two parts, part 1: nurses' demographic data, part 2: Self administrated sheet for nurses' knowledge about triage system. 2nd tool: Nurse's Observational checklist.3rd tool: Nurse's communication and interpersonal relationships Observation Checklist. Results: The majority of nursing personnel had good level of knowledge regarding triage system in post program and slightly decline at follow up as compared with preprogram phase and there were statistical significant differences between pre- training program implementation and immediately, as well 2 months post training program implementation among the studied nurses regarding total level of practice at P-value ≤ 0.05 also the majority of them had satisfactory level of communication skills practice post educational training program implementation. Conclusion: The study concluded that there was highly statistically significant positive correlation between total knowledge among the studied nurses and total nurse’s performance regarding triage system. Recommendations: Continuous training programs or sessions must emphasize on all aspects of triage system for nurses, increasing and applying for the triage training program, information and research findings should be disseminated online
Achieving The Nutritional Goal Of Burn Patients In A Referral Hospital In The Northern Region Of Brazil
Authors: Almeida Taianara Tocantins Gomes , Nascimento Alex Francisco Pinto , Vieira Geovana Parra , Fernandez Raissa , Lopes Edilssa Carla Dias
Published: November 2024

Background: Burns represent a significant health challenge, not only due to the pain and suffering they cause, but also due to metabolic complications. Oral nutritional therapy is a powerful tool in the recovery of these patients, as the burn requires double the energy demands. Therefore, achieving the nutritional goal in burn patients should be considered a priority in clinical management. Materials and Methods: Patients admitted to the Burn Treatment Center at a reference hospital in the North region were evaluated. For nutritional diagnosis, the gold standard tools for nutritional risk analysis were applied, Nutritional Risk Screening (NRS-2002) for adults and Screening Tool for Risk on Nutritional Status and Growth (Strongkids, 2012) for children. These are validated low-cost and non-invasive methods. Monitoring the achievement of VET and protein was carried out through food records and the percentages achieved in accordance with the prescribed calories and proteins were calculated. Results: 22 adult patients were evaluated. Of these, 15 men and 7 women, with an average age of 35.8 years. The assessment revealed 7% malnourished, 67% eutrophic, 33% obese and 13% obese. Adults averaged 2026 cal/day with 112% VET attainment and 90g protein with 125% intake. It is worth highlighting the joint action of nutrition professionals with the prescription of hypercaloric and hyperprotein preparations to adapt to the needs recommended for burn patients, in addition to Oral Nutritional Therapy (ONT), with an increase of 600cal/day and 40g of proteins. The use of hypercaloric and hyperprotein supplementation in burn patients is a strong ally in diet therapy, given the catabolic state and high risk of depletion. Among the children's audience, 7 children were served: 4 boys and 3 girls, an average age of 4.4 years. The nutritional diagnosis showed 85% in eutrophy, and 15% in nutritional risk. The VET of this group was on average 1215 cal and 39g of protein. Children achieved an average of 142% of daily VET and 175% of protein needs. To this end, 85% used TNO, accounting for 300 cal and 7.6 g of additional protein to the oral diet. Conclusion: Achieving the nutritional goals prescribed for burn patients has a significant impact on the meffectiveness of treatment
N-terminal Glycine Analysis for the Determination of the Proteolytic Activity of Thrombin
Authors: Magnusson Staffan
Published: June 2018

In the method presented in this paper for the assay of thrombin activity, N-terminal amino acids are determined with the phenylisothiocyanate method of Edman. Highly purified bovine fibrinogen is proteolyzed by thrombin under strictly defined conditions. The increase in N-terminal glycine is then directly proportional to the activity of the thrombin. Five different thrombin preparations were standardized with this N-terminal method and with a clotting method. The results obtained with the two methods are in good agreement. Because the N-terminal method is accurate and highly specific for thrombin it is proposed as standard method for the chemical determination of thrombin activity. One NIH unit of thrombin was found to make 0.4 μimoles of glycine appear in N-terminal position.
Factor VII: its Turnover Rate and its Possible Role in Thrombogenesis
Authors: Loeliger E. A , Esch B. v. d , ter Haar Romeny-Wachter C. Ch , Booij H. L
Published: June 2018

The range of the hourly turnover rate of factor VII, found in 17 normal individuals, 14 patients with thrombo-embolic diseases and 3 patients with congential hypoproconvertinaemia, was 11.1—16.6% of the total body pool of factor VII (mean normal value 13.8%). The possible significance of this rapid turnover rate of factor VII in prophylactic anticoagulant treatment with 4-hydroxycoumarin derivatives is stressed.
Haploinsufficiency of A20 and other paediatric inflammatory disorders with mucosal involvement
Authors: Aeschlimann Florence A. , Laxer Ronald M.
Published: June 2018

Purpose of review

This review aims at summarizing the current knowledge of A20 haploinsufficiency and other paediatric inflammatory disorders with mucosal involvement.

Recent findings

A20 haploinsufficiency is a newly described autoinflammatory disease caused by loss-of-function mutations in TNFAIP3 that result in the activation of the nuclear factor (NF)-kB pathway. Patients may present with dominantly inherited, early-onset systemic inflammation and a Behçet-like disease, or a variety of autoinflammatory and autoimmune features. In Behçet disease, recent literature provides insights into genetic susceptibility and emerging treatment options; in addition, the first paediatric classification criteria were published. Recent advances in periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA) suggest that the disease has a complex underlying genetic mechanism and in some cases is inherited in an autosomal dominant pattern with reduced penetrance phenotype in many family members. Activation of the pyrin inflammasome through the RoA signalling pathway uncovers an interesting molecular connection between hyperimmunoglobulinemia D syndrome and familial Mediterranean fever. The description of new monogenic types of inflammatory bowel disease (IBD) may provide novel insights into disease pathogenesis. Finally, recent studies highlighted the role of gut microorganisms and dysbiosis in IBD.

Monogenic diseases such as A20 haploinsufficiency may help to advance our understanding of disease pathogenesis and to develop targeted therapies for more common, multifactorial disorders with mucosal inflammation.
A 12-Month Open-Label Extension Study of the Safety and Tolerability of Lisdexamfetamine Dimesylate for Major Depressive Disorder in Adults
Authors: Richards Cynthia , Iosifescu Dan V. , Mago Rajnish , Sarkis Elias , Geibel Brooke , Dauphin Matthew , McIntyre Roger S. , Weisler Richard , Brawman-Mintzer Olga , Gu Joan , Madhoo Manisha
Published: June 2018

Purpose/Background

Psychostimulant augmentation is considered a potential treatment strategy for individuals with major depressive disorder who do not adequately respond to antidepressant monotherapy. The primary objective of this 12-month open-label extension study was to evaluate the safety and tolerability of lisdexamfetamine dimesylate (LDX) as augmentation therapy to an antidepressant in adults with major depressive disorder.

Methods/Procedures

Eligible adults who completed 1 of 3 short-term antecedent LDX augmentation of antidepressant monotherapy studies were treated with dose-optimized LDX (20–70 mg) for up to 52 weeks while continuing on the index antidepressant (escitalopram, sertraline, venlafaxine extended-release, or duloxetine) assigned during the antecedent short-term studies. Safety and tolerability assessments included the occurrence of treatment-emergent adverse events and vital sign changes.

Findings/Results

All 3 antecedent studies failed to meet the prespecified primary efficacy endpoint, so this open-label study was terminated early. Headache (15.5% [241/1559]), dry mouth (13.6% [212/1559]), insomnia (13.1% [204/1559]), and decreased appetite (12.1% [189/1559]) were the most frequently reported treatment-emergent adverse events. The greatest mean ± SD increases observed for systolic and diastolic blood pressure and for pulse were 2.6 ± 10.85 and 1.7 ± 7.94 mm Hg and 6.9 ± 10.27 bpm, respectively. Monitoring determined that less than 1% of participants experienced potentially clinically important changes in systolic blood pressure (10 [0.6%]), diastolic blood pressure (8 [0.5%]), or pulse (6 [0.4%]).

Implications/Conclusions

The overall safety and tolerability of long-term LDX augmentation of antidepressant monotherapy was consistent with the profiles of the short-term antecedent studies, with no evidence of new safety signals.
Anemia in conventional hemodialysis: Finding the optimal treatment balance
Authors: Hasegawa Takeshi , Koiwa Fumihiko , Akizawa Tadao
Published: June 2018

Renal anemia is a serious and common complication in hemodialysis (HD) patients. The introduction of erythropoiesis‐stimulating agents (ESAs) has dramatically improved hemoglobin levels and outcomes. Several interventional studies reported that excessive correction of anemia and the massive use of ESA can trigger cardiovascular disease (CVD), and consequently may worsen the prognosis of patients undergoing HD. Therefore, it has been widely recognized that large doses of ESA should be used with caution. An effective use of iron preparations is required to yield the optimal effect of ESA. It is well‐known that iron utilization is inhibited under pathological conditions, such as chronic inflammation, resulting in ESA resistance. It is postulated that a new class of therapeutic agents for renal anemia, hypoxia inducible factor prolyl hydroxylase (HIF‐PH) inhibitors, will have beneficial treatment effects in patients on HD. HIF is induced by hypoxia and promotes erythropoietin production. In the absence of a hypoxic state, HIF is decomposed by the HIF catabolic enzyme. HIF‐PH inhibitors inhibit this degrading enzyme and stimulate endogenous erythropoietin production via HIF induction. Additionally, HIF‐PH inhibitors promote effective utilization of iron and raise erythropoietin to physiological concentrations. Accordingly, HIF‐PH inhibitors improve anemia and iron metabolism. It appears that this effect persists irrespective of chronic inflammatory conditions. HIF‐PH inhibitors do not overshoot erythropoietin above physiological concentrations like ESAs. Therefore, it is hypothesized that HIF‐PH inhibitors would not increase the risk of CVD in patients undergoing HD.
Wild Chinook salmon productivity is negatively related to seal density and not related to hatchery releases in the Pacific Northwest
Authors: Nelson Benjamin W. , Walters Carl J. , Trites Andrew W. , McAllister Murdoch K.
Published: June 2018

Predation risk and competition among conspecifics significantly affect survival of juvenile salmon, but are rarely incorporated into models that predict recruitment in salmon populations. Using densities of harbour seals (Phoca vitulina) and numbers of hatchery-released Chinook salmon (Oncorhynchus tshawytscha) smolts as covariates in spatially structured Bayesian hierarchical stock–recruitment models, we found significant negative correlations between seal densities and productivity of Chinook salmon for 14 of 20 wild Chinook populations in the Pacific Northwest. Changes in numbers of seals since the 1970s were associated with a 74% decrease (95% CI: −85%, −64%) in maximum sustainable yield in Chinook stocks. In contrast, hatchery releases were significantly correlated with Chinook productivity in only one of 20 populations. Our findings are consistent with recent research on predator diets and bioenergetics modeling that suggest there is a relationship between harbour seal predation on juvenile Chinook and reduced marine survival in parts of the eastern Pacific. Forecasting, assessment, and recovery efforts for salmon populations of high conservation concern should thus consider including biotic factors, particularly predator–prey interactions.
The Right of the Child for Survival and Healthy Development and Problems of its Realization in the Russian Federation
Authors: KVITKOVSKAYA Angelina Anatolievna , MEYLIS Ekaterina Borisovna , PROKHOROVA Larisa Viktorovna , RABETS Anna Maximovna , TCHINARYAN Elena Olegovna
Published: June 2018

The paper is devoted to the problems of implementation and protection of children's rights to life and to health which are highly relevant in the world community, including the Russian Federation. The authors investigate the norms of all the branches of law, within the legal system of the Russian Federation, where measures of protection of this right and responsibility for its violation are established. In addition, the current Russian legislation on health protection, compulsory health insurance, circulation of medicines, transplantation of organs, tissues, and other aspectsare analyzed thoroughly and comprehensively. The international and foreign experience in rights regulation and the opinions of Russian and foreign scientists on various contentious issues relating to understanding of the juvenile's right to survival and healthcare are thoroughly revealed in the paper. Researchers conclude about the apparent lack and low efficiency of legal tools ensuring the realization and protection of this right in the national legislation of the Russian Federation. The study is intended for scholars, professors, graduate students and law students as well as for specialists, whose activities are directly related to the protection of the rights and interests of juveniles.
Az autoimmun thyreoiditis, a kétoldali papillaris pajzsmirigy-carcinoma, a nyaki thyreolipoma és a diabetes mellitus együttes előfordulása
Authors: Steiner Tamás , Péter Ilona , Pogány Péter , Lantos András , Sándor Zsuzsa , Téglás Melinda , Koltai Pál
Published: June 2018

Abstract:

Thyrolipoma or thyroid adenolipoma is an extremely rare form of thyroid adenoma, which also contains mature adipose tissue and follicles covered with fibrous capsule. We present the case of the growing cervical lesion of a 52-year-old female with diabetes, which was removed during total thyreoidectomy. Autoimmune thyroiditis, bilateral papillary carcinoma and cervical thyrolipoma have been identified by the histopathological examination of the thyroid gland. Orv Hetil. 2018; 159(25): 1024–1032.
Кто и как оценивает выборы: особенности экспертного опроса качества региональных выборов 13 сентября 2015 года в России
Authors: Завадская Маргарита Андреевна , Бедерсон Всеволод Дмитриевич
Published: June 2018

Маргарита Андреевна Завадская – старший научный сотрудник, Лаборатория сравнительных социальных исследований, Национальный исследовательский университет «Высшая школа экономики»; научный сотрудник, Европейский университет в Санкт-Петербурге. Адрес: 191187, Санкт-Петербург, ул. Седова, д. 55, к. 1. E-mail: mzavadskaya@hse.ru

Всеволод Дмитриевич Бедерсон – кандидат политических наук, младший научный сотрудник, Институт философии и права УрО РАН, сотрудник Центра сравнительных исторических и политических исследований ПГНИУ, старший преподаватель кафедры политических наук ПГНИУ. Адрес: 620990, Екатеринбург, ул. Софьи Ковалевской,  д. 16. E-mail: vsbederson@gmail.com

Цитирование: Завадская М.А., Бедерсон В.Д. (2018) Кто и как оценивает выборы: особенности экспертного опроса качества региональных выборов 13 сентября 2015 года  в России // Мир России. Т. 27. № 3. С. 82–106. DOI: 10.17323/1811-038X-2018-27-3-82-106

 

Метод оценки с помощью экспертных опросов весьма распространен в современных сравнительных исследованиях, однако возникает вопрос, насколько надежными и валидными являются результаты подобных опросов, полученных в условиях (1) политизации предмета исследования (проблема чувствительности), (2) политического режима, характеризуемого экспертами как «электоральный авторитаризм», и (3) продолжающегося процесса профессионализации экспертного сообщества. Основываясь на материалах экспертного опроса проекта Electoral Integrity Project, авторы исходят из предположения о том, что эти три фактора будут систематически влиять на характер экспертных оценок, оставаясь источниками смещения (bias), которые необходимо учитывать при использовании результатов экспертных опросов в дальнейших исследованиях. Цель исследования – выявить, есть ли систематические смещения в экспертных оценках, и если они есть, то каковы их источники. Результаты анализа показывают, что в экспертных оценках в качестве источников смещения имеют значение степень персональной «лояльности» или «оппозиционности» эксперта (голосования за партию власти или оппозицию), а также степень доверия телевидению.
Relative potential of seed yield component traits as selection criteria in the segregating generations of a desi × kabuli cross of chickpea
Authors: Santosh H. B. , Bharadwaj C. , Hegde V. S. , Savitha S. , Angadi C. , Kumar J.
Published: June 2018

To assess the response to early generation selection in chickpea, a total of 150 F4 progenies derived from selection for total branches per plant, pods per plant, seeds per pod, seed yield per plant and 100-seed weight as independent selection criteria in F2 population of Pusa 362 (desi) × PG 0515 (kabuli) cross were evaluated along with their parents and unselected F2 bulk. The F2 population revealed high variability for all the yield components and transgressive segregation for all traits except 100-seed weight. Mean of the F4 families relative to the corresponding F2 plants was high, indicating effectiveness of early generation selection for all characters studied except branch number per plant. Significant correlated response for seed yield was also observed in F4. Based on realized response to selection as percentage of mean, realized heritability and realized generalized response values, we suggest utilization of pods per plant, seed yield per se and 100-seed weight as selection criteria in desi-kabuli introgression breeding for higher genetic gains.
Influence of seed priming and different irrigation levels on growth parameters of cowpea [Vigna unguiculata (L.) Walp)
Authors: Arun M. N. , Hebbar S. Shankara , Bhanuprakash K. , Senthivel T. , Nair A. K. , Pandey D. Pratima
Published: June 2018

A field study was conducted during summer season of 2012 and 2013 at Indian Institute of Horticultural Research in Bangalore, India to evaluate if priming could improve grain yield and water use efficiency of cowpea under limited water supply condition through drip system. Seed variety Arka Garima received the following priming treatments: they were soaked in GA3,CaCl2, ammonium molybdate, KBr, MgNO3, ZnSO4 solutions and water (hydropriming) for 24 hours at 15o C. Crop was subjected to three irrigation intervals in which the irrigation was applied at 0.9, 0.7, 0.5 Epan Replenishment of evaporation. Plant height, number of trifoliate leaves, total dry matter accumulation, number of pods per plant, number of seeds per pod, 1000 seed weight and grain and biological yield were increased by different priming treatments compared to control. Seed priming increased the LAI, RGR, CGR and NAR at all irrigation regimes. Results suggest that the use of seed priming with either GA3 (100ppm) or ammonium molybdate (10-3 M) for 24 hours at low concentration can be helpful in cowpea under both optimum as well as limited water conditions.
Purwarupa Alat Kalibrasi Kerataan Bidang Kerja menggunakan Laser Sensor
Authors: SUGANDI BUDI , WIYONO SURADI
Published: June 2018

ABSTRAKSalah satu elemen teknologi pendukung dari industri manufaktur elektronika adalah mesin Die Attach. Mesin ini digunakan pada proses assembly komponen dengan metode pick and place komponen pada material. Sebagai proses yang penting dalam industri manufaktur, mesin ini memerlukan kalibrasi secara reguler dan tepat yang akan menjadi kunci sukses dari kualitas suatu produksi. Penelitian ini bertujuan membuat suatu purwarupa alat yang digunakan sebagai pengontrol kalibrasi dengan menggunakan laser sensor. Proses kalibrasi dilakukan dengan cara mengukur kerataan titip sisi work holder menggunakan laser sensor. Kerataan didapatkan dengan membandingkan jarak yang terukur oleh laser sensor pada tiap titik uji. Jarak yang sama pada tiap titik uji menunjukkan kerataan dari work holder. Pergerakan laser sensor dikontrol oleh dua buah motor yang bergerak ke arah sumbu X dan Y. Alat ini telah diuji dengan mengkalibrasi pada empat sisi work holder. Hasil pengujian kemudian dibandingkan dengan pengukuran manual dan didapatkan error rata-rata pengukuran sekitar 4%.Kata kunci: Laser sensor, kerataan, kalibrasi, die attach machine ABSTRACTOne of the element technology supporting an industrial manufacturing is Die Attach machine. This machine is used at component assembly using component pick and place. As an important process, this machine requires regular and precise calibration to support quality of the product. This research aims to build a prototype system using laser sensor which can be used as calibration instrument. The callibration proses was done by measuring the flatness of each side of work holder using laser sensor. The flatness was obtained by comparing the distance of each testing point. The same distance on each testing point represented the flatness of the wrok holder. The movement of laser sensor was controlled by two motors which moved to X and Y axis. The system has been tested to calibrate each side of work holder. The experimental results were then compare with manual measurement and showed the measurement error about 4%.Keywords: Laser sensor, flatness, callibration, die attach machine.
IBM PEMBANGUNAN SARANA BELAJAR RUMAH CERDAS QURAN DI DESA PERAWANG DAN DESA WONOSARI PROVINSI RIAU
Authors: Nazrantika Nazrantika , Rosmida Rosmida
Published: June 2018

Tujuan IbM Pembangunan Sarana belajar Rumah Cerdas Qur’an (RCQ) untuk memfasilitasi para remaja dan anak-anak muslim (santri) untuk belajar dalam meningkatkan keahlian membacaal-Qur’an dengan tartil, yaitu membangun sarana belajar. Metode pelaksanaan dimulai dari persiapan dengan melakukan rapat koordinasi bersama kedua mitra, penyuluhan jadwal pelaksanaan kegiatan. Hasil dari pelaksanaan IbM ini adalah kedua mitra mendapatkan sarana tempat belajar berupa Gazeebo. Desa Perawang memperoleh 1 unit gazebo ukuran 3x3m dan Desa Wonosari memperoleh 2 unit gazebo ukuran 3,5x3,5m dan 1 unit 4x6m.
Da mídia de massa às novas mídias: aspectos evolutivos da comunicação em Marketing
Authors: Schaeffer Cristian Luis , Luce Fernando Bins
Published: June 2018

O objetivo deste artigo consiste em analisar, com base no levantamento de artigos e bibliografias da área, os aspectos evolutivos e o papel da comunicação em marketing com o surgimento das novas mídias. Foram estudados conceitos como Marketing, Mix de Marketing, promoção/comunicação, mídia de massa e novas mídias, além do impacto causado pela tecnologia. A análise dessas informações permitiu traçar um quadro geral com as principais características de ambas as categorias de mídias e os fatores que contribuíram para essa evolução, além de avaliar os desafios para a comunicação em Marketing. As novas mídias exigiram uma mudança no papel e no pensamento do Marketing, já que a comunicação impessoal cedeu espaço para a interatividade. E cabe aqui destacar que a área de Marketing está se esforçando para acompanhar essas mudanças.  The purpose of this article is to analyze, based on the gathering of articles and bibliographies of the area, the evolutive aspects and the role of communication in marketing with the emergence of new media. Concepts such as Marketing, Marketing Mix, promotion/ communication, mass media and new media were studied, as well as the impact caused by technology. The analysis of this information allowed to chart a general framework with the main characteristics of both categories of media and the factors that contributed to this evolution, besides evaluating the challenges for communication in Marketing. The new media required a change in the role and thinking of Marketing, since impersonal communication gave way to interactivity. And it should be noted here that the Marketing area is striving to keep up with these changes.