bluuebunny/crossref_metadata_2025 huggingface dataset:
Oceanographic Determinants of the Abundance of Common Dolphins (Delphinus delphis) in the South of Portugal
Authors: Castro Joana , Couto Ana , Borges Francisco O. , Cid André , Laborde Marina I. , Pearson Heidi C. , Rosa Rui
Published: August 2020

Off mainland Portugal, the common dolphin (Delphinus delphis) is the most sighted cetacean, although information on this species is limited. The Atlantic coast of Southern Portugal is characterized by an intense wind-driven upwelling, creating ideal conditions for common dolphins. Using data collected aboard whale-watching boats (1929 sightings and 4548 h effort during 2010–2014), this study aims to understand the relationships between abundance rates (AR) of dolphins of different age classes (adults, juveniles, calves and newborns) and oceanographic [chlorophyll a (Chl-a) and sea surface temperature (SST)] variables. Over 70% of the groups contained immature animals. The AR of adults was negatively related with Chl-a, but not related to SST values. The AR of juveniles was positively related with SST. For calves and newborns, although the relationship between SST and AR is similar to that observed for juveniles, the effect could not be distinguished from zero. There was no relationship between Chl-a levels and the AR of juveniles, calves and newborns. These results corroborate previous findings that common dolphins tend to occur in highly productive areas demonstrating linkages between their abundance and oceanographic variables, and that this region may be a potential nursery ground.
Transcriptomic Analysis of a Susceptible African Maize Line to Fusarium verticillioides Infection
Authors: Lambarey Humaira , Moola Naadirah , Veenstra Amy , Murray Shane , Suhail Rafudeen Mohamed
Published: August 2020

Maize (Zea mays L.) is a staple crop providing food security to millions of people in sub Saharan Africa. Fusarium verticillioides, an important fungal pathogen, infects maize causing ‘Fusarium Ear Rot’ disease, which decreases maize kernel yield and the quality of the crop harvested. Currently, no African maize line is completely resistant to infection by F. verticillioides. This study investigated an African maize line, Zea mays CML144, infected with F. verticillioides. Analysis of morphological characteristics showed significant differences between mock-infected and infected plants. RNA-sequencing (RNA-seq) was conducted on plants 14 days post-inoculation to identify differentially expressed genes (DEGs) involved in F. verticillioides infection. Analysis of RNA-seq data revealed DEGs that were both significantly up- and down-regulated in the infected samples compared to the mock-infected control. The maize TPS1 and cytochrome P450 genes were up-regulated, suggesting that kauralexins were involved in the CML144 defense response. This was substantiated by kauralexin analyses, which showed that kauralexins, belonging to class A and B, accumulated in infected maize tissue. Gene ontology terms relating to response to stimulus, chemical stimulus and carbohydrate metabolic processes were enriched, and the genes belonging to these GO-terms were down-regulated. Quantitative real-time PCR was performed on selected DEGs and measurement of phytoalexin accumulation validated the RNA-seq data and GO-analysis results. A comparison of DEGs from this study to DEGs found in F. verticillioides (ITEM 1744) infected susceptible (CO354) and resistant (CO441) maize genotypes in a previous study, matched 18 DEGs with 17 up-regulated and one down-regulated, respectively. This is the first transcriptomic study on the African maize line, CML144, in response to F. verticillioides infection.
Understory Vegetation Change Following Woodland Reduction Varies by Plant Community Type and Seeding Status: A Region-Wide Assessment of Ecological Benefits and Risks
Authors: Monaco Thomas A. , Gunnell Kevin L.
Published: August 2020

Woodland encroachment is a global issue linked to diminished ecosystem services, prompting the need for restoration efforts. However, restoration outcomes can be highly variable, making it difficult to interpret the ecological benefits and risks associated with woodland-reduction treatments within semiarid ecosystems. We addressed this uncertainty by assessing the magnitude and direction of vegetation change over a 15-year period at 129 sagebrush (Artemisia spp.) sites following pinyon (Pinus spp.) and juniper (Juniperus spp.) (P–J) reduction. Pretreatment vegetation indicated strong negative relationships between P–J cover and the abundance of understory plants (i.e., perennial grass and sagebrush cover) in most situations and all three components differed significantly among planned treatment types. Thus, to avoid confounding pretreatment vegetation and treatment type, we quantified overall treatment effects and tested whether distinct response patterns would be present among three dominant plant community types that vary in edaphic properties and occur within distinct temperature/precipitation regimes using meta-analysis (effect size = lnRR = ln[posttreatment cover/pretreatment cover]). We also quantified how restoration seedings contributed to overall changes in key understory vegetation components. Meta-analyses indicated that while P–J reduction caused significant positive overall effects on all shrub and herbaceous components (including invasive cheatgrass [Bromus tectorum] and exotic annual forbs), responses were contingent on treatment- and plant community-type combinations. Restoration seedings also had strong positive effects on understory vegetation by augmenting changes in perennial grass and perennial forb components, which similarly varied by plant community type. Collectively, our results identified specific situations where broad-scale efforts to reverse woodland encroachment substantially met short-term management goals of restoring valuable ecosystem services and where P–J reduction disposed certain plant community types to ecological risks, such as increasing the probability of native species displacement and stimulating an annual grass-fire cycle. Resource managers should carefully weigh these benefits and risks and incorporate additional, appropriate treatments and/or conservation measures for the unique preconditions of a given plant community in order to minimize exotic species responses and/or enhance desirable outcomes.
Displacement Analysis and Design of a (2–RRU)–URR Parallel Mechanism Performing 2R1T Output Motion for Thumb Rehabilitation
Authors: Choi Woo-hyeok , Takeda Yukio
Published: August 2020

The thumb assists other fingers, and any damage in its functionality prevents the human hand from performing dexterous functions. In this paper, the kinematic design of the (2–RRU)–URR parallel mechanism as the application of the thumb rehabilitation device is proposed. This mechanism is an over-constrained mechanism capable of achieving the required mobility with fewer joints. Three degrees of freedom exist—two rotational and one translational mobility—that are related to each thumb movement: adduction–abduction and flexion–extension. Considering the narrow space of the hand, actuators are designed to divide its placement into the surface of the palm. To avoid the collisions between the device and the hand, an offset was adopted. The displacement analysis problem is solved by dividing it into two parts: the planar motion generator (PMG) and orientation generator (OG), according to each functional motion, and the corresponding equations and procedures are presented. To clarify the basic characteristics of this mechanism, the reachable workspace of the PMG and rotational ability and sensitivity of the OG is demonstrated numerically. Because a large input torque difference is dangerous in the rehabilitation mechanism, the effective workspace is determined according to the magnitude of the input torque differences and compared with the measured thumb movements.
Assessing Climate Change Impact on Soil Salinity Dynamics between 1987–2017 in Arid Landscape Using Landsat TM, ETM+ and OLI Data
Authors: Bannari Abderrazak , Al-Ali Zahra M.
Published: August 2020

This paper examines the climate change impact on the spatiotemporal soil salinity dynamics during the last 30 years (1987–2017) in the arid landscape. The state of Kuwait, located at the northwest Arabian Peninsula, was selected as a pilot study area. To achieve this, a Landsat- Operational Land Imager (OLI) image acquired thereabouts simultaneously to a field survey was preprocessed and processed to derive a soil salinity map using a previously developed semi-empirical predictive model (SEPM). During the field survey, 100 geo-referenced soil samples were collected representing different soil salinity classes (non-saline, low, moderate, high, very high and extreme salinity). The laboratory analysis of soil samples was accomplished to measure the electrical conductivity (EC-Lab) to validate the selected and used SEPM. The results are statistically analyzed (p ˂ 0.05) to determine whether the differences are significant between the predicted salinity (EC-Predicted) and the measured ground truth (EC-Lab). Subsequently, the Landsat serial time’s datasets acquired over the study area with the Thematic Mapper (TM), Enhanced Thematic Mapper Plus (ETM+) and OLI sensors during the last three decades over the intervals (1987, 1992, 1998, 2000, 2002, 2006, 2009, 2013, 2016 and 2017) were radiometrically calibrated. Likewise, the datasets were atmospherically and spectrally normalized by applying a semi-empirical line approach (SELA) based on the pseudo-invariant targets. Afterwards, a series of soil salinity maps were derived through the application of the SEPM on the images sequence. The trend of salinity changes was statistically tested according to climatic variables (temperatures and precipitations). The results revealed that the EC-Predicted validation display a best fits in comparison to the EC-Lab by indicating a good index of agreement (D = 0.84), an excellent correlation coefficient (R2 = 0.97) and low overall root mean square error (RMSE) (13%). This also demonstrates the validity of SEPM to be applicable to the other images acquired multi-temporally. For cross-calibration among the Landsat serial time’s datasets, the SELA performed significantly with an RMSE ≤ ± 5% between all homologous spectral reflectances bands of the considered sensors. This accuracy is considered suitable and fits well the calibration standards of TM, ETM+ and OLI sensors for multi-temporal studies. Moreover, remarkable changes of soil salinity were observed in response to changes in climate that have warmed by more than 1.1 °C with a drastic decrease in precipitations during the last 30 years over the study area. Thus, salinized soils have expanded continuously in space and time and significantly correlated to precipitation rates (R2 = 0.73 and D = 0.85).
IHS-GTF: A Fusion Method for Optical and Synthetic Aperture Radar Data
Authors: Shao Zhenfeng , Wu Wenfu , Guo Songjing
Published: August 2020

Optical and Synthetic Aperture Radar (SAR) fusion is addressed in this paper. Intensity–Hue–Saturation (IHS) is an easily implemented fusion method and can separate Red–Green–Blue (RGB) images into three independent components; however, using this method directly for optical and SAR images fusion will cause spectral distortion. The Gradient Transfer Fusion (GTF) algorithm is proposed firstly for infrared and gray visible images fusion, which formulates image fusion as an optimization problem and keeps the radiation information and spatial details simultaneously. However, the algorithm assumes that the spatial details only come from one of the source images, which is inconsistent with the actual situation of optical and SAR images fusion. In this paper, a fusion algorithm named IHS-GTF for optical and SAR images is proposed, which combines the advantages of IHS and GTF and considers the spatial details from the both images based on pixel saliency. The proposed method was assessed by visual analysis and ten indices and was further tested by extracting impervious surface (IS) from the fused image with random forest classifier. The results show the good preservation of spatial details and spectral information by our proposed method, and the overall accuracy of IS extraction is 2% higher than that of using optical image alone. The results demonstrate the ability of the proposed method for fusing optical and SAR data effectively to generate useful data.
Vibration Data Processing for Bedload Monitoring in Underwater Environments
Authors: Vasile Gabriel
Published: August 2020

This paper proposes a novel data processing framework dedicated to bedload monitoring in underwater environments. After calibration, by integration the of total energy in the nominal bandwidth, the proposed experimental set-up is able to accurately measure the mass of individual sediments hitting the steel plate. This requires a priori knowledge of the vibration transients in order to match a predefined dictionary. Based on unsupervised hierarchical agglomeration of complex vibration spectra, the proposed algorithms allow accurate localization of the transients corresponding to the shocks created by sediment impacts on a steel plate.
A Dual-Connectivity Mobility Link Service for Producer Mobility in the Named Data Networking
Authors: Choi Ju-Ho , Cha Jung-Hwan , Han Youn-Hee , Min Sung-Gi
Published: August 2020

With the exponential growth of Cyber-Physical Systems (CPSs) technologies, the Internet of Things (IoT) infrastructure has evolved from built-in static infrastructure to a flexible structure applicable to various mobile environments. In this Internet of Mobile Things (IoMT) environment, each IoT device could operate simultaneously as a provider and consumer of information, and could provide new services through the exchange of such information. Named Data Networking (NDN), which could request data by content name rather than location (IP address), is suitable for such mobile IoT environments. However, in the current Named Data Networking (NDN) specification, producer mobility is one of the major problems in need of remedy. Previously proposed schemes for producer mobility use an anchor to hide the producer’s movement from consumers. As a result, they require a special anchor node and a signaling procedure to track the current locations of contents. A few anchorless schemes have also been proposed, but they still require mobility signaling and all NDN routers on the signaling path must understand the meaning of the signaling. We therefore propose an anchorless producer mobility scheme for the NDN. This scheme uses a dual-connectivity strategy that can be expressed as a soft handover. Whenever a producer changes its NDN Access Router (NAR), the new mobility link service located on the mobile producer’s old NDN face repairs the old link so that the connectivity with the pNAR can be maintained for a while. The old NDN face is removed after the new location information on the contents of the producer is disseminated over the NDN network by the Named-data Link State Routing Protocol (NLSR) routing protocol at the nNAR. The new mobility link service decouples connection and transaction to hide the collapse of the link. Therefore, the NDN’s mobility procedure could be simplified as the handover is defined as transaction completion as opposed to a breakdown of links. The proposed scheme prevents the routing information from being abruptly outdated due to producer mobility. Our simulation results show seamless handover when the producer changes its default access router.
Sub-Millisecond Phase Retrieval for Phase-Diversity Wavefront Sensor
Authors: Wu Yu , Guo Youming , Bao Hua , Rao Changhui
Published: August 2020

We propose a convolutional neural network (CNN) based method, namely phase diversity convolutional neural network (PD-CNN) for the speed acceleration of phase-diversity wavefront sensing. The PD-CNN has achieved a state-of-the-art result, with the inference speed about 0.5 ms, while fusing the information of the focal and defocused intensity images. When compared to the traditional phase diversity (PD) algorithms, the PD-CNN is a light-weight model without complicated iterative transformation and optimization process. Experiments have been done to demonstrate the accuracy and speed of the proposed approach.
In-Ear SpO2: A Tool for Wearable, Unobtrusive Monitoring of Core Blood Oxygen Saturation
Authors: Davies Harry J. , Williams Ian , Peters Nicholas S. , Mandic Danilo P.
Published: August 2020

The non-invasive estimation of blood oxygen saturation (SpO2) by pulse oximetry is of vital importance clinically, from the detection of sleep apnea to the recent ambulatory monitoring of hypoxemia in the delayed post-infective phase of COVID-19. In this proof of concept study, we set out to establish the feasibility of SpO2 measurement from the ear canal as a convenient site for long term monitoring, and perform a comprehensive comparison with the right index finger—the conventional clinical measurement site. During resting blood oxygen saturation estimation, we found a root mean square difference of 1.47% between the two measurement sites, with a mean difference of 0.23% higher SpO2 in the right ear canal. Using breath holds, we observe the known phenomena of time delay between central circulation and peripheral circulation with a mean delay between the ear and finger of 12.4 s across all subjects. Furthermore, we document the lower photoplethysmogram amplitude from the ear canal and suggest ways to mitigate this issue. In conjunction with the well-known robustness to temperature induced vasoconstriction, this makes conclusive evidence for in-ear SpO2 monitoring being both convenient and superior to conventional finger measurement for continuous non-intrusive monitoring in both clinical and everyday-life settings.
CeO2-Based Two-Dimensional Layered Nanocomposites Derived from a Metal–Organic Framework for Selective Electrochemical Dopamine Sensors
Authors: Ge Chengjie , Ramachandran Rajendran , Wang Fei
Published: August 2020

In this work, we demonstrate the incorporation of two-dimensional (2D) layered materials into a metal–organic framework (MOF) derived from one-dimensional (1D) cerium oxide (CeO2) for the electrochemical detection of dopamine. Ce-MOF was employed as a sacrificial template for preparing CeO2 with 2D materials by the pyrolysis process. The influence of the pyrolysis temperature was studied to achieve a better crystal structure of CeO2. Siloxene improved the dopamine sensing performance of CeO2 compared with graphitic carbon nitride (g-C3N4) due to the basal plane surface oxygen and hydroxyl groups of 2D siloxene. Under optimal conditions, the fabricated CeO2/siloxene electrode exhibited a detection limit of 0.292 μM, with a linear range from 0.292 μM to 7.8 μM. This work provides a novel scheme for designing the CeO2 material with siloxene for excellent dopamine sensors, which could be extended towards other biosensing applications.
Control Methods for Transradial Prostheses Based on Remnant Muscle Activity and Its Relationship with Proprioceptive Feedback
Authors: Grushko Stefan , Spurný Tomáš , Černý Martin
Published: August 2020

The loss of a hand can significantly affect one’s work and social life. For many patients, an artificial limb can improve their mobility and ability to manage everyday activities, as well as provide the means to remain independent. This paper provides an extensive review of available biosensing methods to implement the control system for transradial prostheses based on the measured activity in remnant muscles. Covered techniques include electromyography, magnetomyography, electrical impedance tomography, capacitance sensing, near-infrared spectroscopy, sonomyography, optical myography, force myography, phonomyography, myokinetic control, and modern approaches to cineplasty. The paper also covers combinations of these approaches, which, in many cases, achieve better accuracy while mitigating the weaknesses of individual methods. The work is focused on the practical applicability of the approaches, and analyses present challenges associated with each technique along with their relationship with proprioceptive feedback, which is an important factor for intuitive control over the prosthetic device, especially for high dexterity prosthetic hands.
Towards Sustainability in E-Banking Website Assessment Methods
Authors: Chmielarz Witold , Zborowski Marek
Published: August 2020

Nowadays, banking services have evolved from offline financial services to online platforms available in the form of websites and mobile applications. While multiple methods exist for evaluation of generic-purpose websites, the appraisal of banking services requires a more sophisticated approach. Multiple factors need to be taken into consideration, revolving not only around technical and usability aspects of the sites, but also considering the economic and anti-crisis factors. Moreover, due to the fact that one of the groups of people interested in banking services assessment are potential clients, which might or might not be technically and theoretically literate, a sustainable approach to banking services evaluation is needed. The main contribution of this paper is a sustainable approach balancing the evaluation accuracy with usage simplicity and computational complexity of evaluation methods. Also, a reference model for banking services evaluation is provided. In practical terms, a set of all significant commercial banking services in Poland is assessed. Last, but not least, a preliminary study of practical applicability of various evaluation methods amongst computer-literate banking clients is performed.
Agroforestry Benefits and Challenges for Adoption in Europe and Beyond
Authors: Sollen-Norrlin Maya , Ghaley Bhim Bahadur , Rintoul Naomi Laura Jane
Published: August 2020

Soil degradation is a global concern, decreasing the soil’s ability to perform a multitude of functions. In Europe, one of the leading causes of soil degradation is unsustainable agricultural practices. Hence, there is a need to explore alternative production systems for enhanced agronomic productivity and environmental performance, such as agroforestry systems (AFS). Given this, the objective of the study is to enumerate the major benefits and challenges in the adoption of AFS. AFS can improve agronomic productivity, carbon sequestration, nutrient cycling, soil biodiversity, water retention, and pollination. Furthermore, they can reduce soil erosion and incidence of fire and provide recreational and cultural benefits. There are several challenges to the adoption and uptake of AFS in Europe, including high costs for implementation, lack of financial incentives, limited AFS product marketing, lack of education, awareness, and field demonstrations. Policies for financial incentives such as subsidies and payments for ecosystem services provided by AFS must be introduced or amended. Awareness of AFS products must be increased for consumers through appropriate marketing strategies, and landowners need more opportunities for education on how to successfully manage diverse, economically viable AFS. Finally, field-based evidence is required for informed decision-making by farmers, advisory services, and policy-making bodies.
Lessons Learned from Teaching Nursing Students about Equality, Equity, Human Rights, and Forced Migration through Roleplay in an Inclusive Classroom
Authors: Okenwa-Emegwa Leah , Eriksson Henrik
Published: August 2020

Inclusive education, sustainable development, and core nursing values all share common goals of promoting diversity, equity, social justice, and inclusion. However, prevailing norms of exclusion may shape health systems and healthcare workers’ attitudes and threaten inclusive patient care. Ongoing global conflicts and violence resulting in growing patient diversity in terms of ethnicity and migration status have led to questions regarding healthcare systems’ preparedness for inclusive nursing. Diversity-rich classrooms and collaborative learning methods, like role play, are inclusive strategies that may be useful in nursing education. The purpose of this paper is to present lessons learned from incorporating role play about forced migration in inclusive nursing classrooms. Various diversity-rich nursing student groups participated in a two-hour role play on forced migration facilitated by youth volunteers from the Swedish Red Cross Society between 2017 and 2019. This study is based on the amplified analysis of qualitative data materials, in the form of notes and summarized feedbacks, obtained from evaluating the role play as a teaching-learning activity. Three themes were identified, specifically, knowledge exchange, existential reflections, and empathy evoked. Findings suggest that working collaboratively in an inclusive environment may improve nursing students’ understanding of the vulnerabilities created by forced migration and to be better prepared for promoting social justice for this group in health care settings.
Does Financial Development Increase Urban Electricity Consumption? Evidence from Spatial and Heterogeneity Analysis
Authors: Liu Shiwen , Li Hongyuan
Published: August 2020

The role of financial development (FD) in China’s environment has attracted extensive attention from scholars, but few studies involved the effect of FD on urban electricity consumption (EC). This paper constructs two spatial panel models to explore the interaction between FD and EC on the basis panel data of 278 cities in China from 2005 to 2016. The results show that electricity consumption of urban residents and industrial sector in China has obvious spatial correlation and unbalanced spatial distribution. Secondly, FD can promote urban industrial electricity consumption (IEC) and urban residential electricity consumption (REC), and it has a greater impact on REC than IEC. Thirdly, spatial heterogeneity is established, and the imbalance of REC and IEC among different regions and urban scales deserves more attention. FD is conducive to enhance REC and IEC in the eastern and western regions. Meanwhile, FD plays an important role in the increase of REC and IEC in small cities, large cities, and megacities of China. Considering the above results, this paper puts forward targeted policy recommendations.
Data Acquisition System for the Characterization of Biomechanical and Ergonomic Thresholds in Driving Vehicles
Authors: Dols Juan F. , Girbés-Juan Vicent , Luna Álvaro , Catalán Javier
Published: August 2020

Directive (EU) 2015/653 on driving licenses has involved the modification of different codes that must appear on driver’s licenses. The definition of specific codes (20.07 and 40.01) compels measurement of the braking and steering forces. Performing practical tests to assess the driving fitness of special drivers will help to determine the maximum force that a driver can apply on primary controls when driving. From that point, definition of car control adaptations required to supply their functional deficiencies can be stated. This article describes a data acquisition system designed and developed for obtaining data from experimental tests based on the execution of habitual driving manoeuvres (braking, lane change and roundabouts). The data gathered will allow for definition of the thresholds of biomechanical values (forces on the steering wheel and brake pedal) and ergonomic values (driver’s upper extremity mobility ranges) necessary for driving motor vehicles. The results have shown that application in real driving tests of the data acquisition system designed provides valid and suitable results for the case studied. Therefore, it will contribute to substantially improving the assessment procedure for drivers in general and for disabled people in particular when obtaining or renewing their driving licenses.
MapOnLearn: The Use of Maps in Online Learning Systems for Education Sustainability
Authors: Liu Sannyuya , Guo Dongpo , Sun Jianwen , Yu Jie , Zhou Dongbo
Published: August 2020

Online learning and teaching have become the primary forms of education during the global pandemic, and online learning systems, which can provide fair educational opportunities for everyone, are increasingly important for sustainability in education. The amount of time a student spends on online learning systems affects the fairness and persistence of sustainability in education. To support personalized learning opportunities, interactive learning, and easy-to-access resources, we propose a map organization and visualization method called MapOnLearn for online learning systems. First, we converted tree-like hierarchical course units (HCUs) and knowledge points (KPs) into a fundamental two-dimensional (2D) map of hierarchically divided polygons and used the map to form containers to manage all learning resources. Then, we used the zoom feature of the map to express the hierarchical structures of knowledge and formulated corresponding rules for displaying information at different levels. Path analysis was applied to express the learning process, and topological processing was adapted to represent the relationships among HCUs and KPs. We developed maps for a high-level math course, a course on data structures, and an English course at a university in China and investigated 264 students and 27 teachers for a semester by using the technology acceptance model (TAM). We found that the map visualization and organization method had a positive impact on the way teachers and students use online learning systems and improved the online learning experience. To attract more students to spend more time on online learning, we hope our method can promote the sustainable development of education.
Momentum Investment Strategy Using a Hidden Markov Model
Authors: Ryou Hosun , Bae Han Hee , Lee Hee Soo , Oh Kyong Joo
Published: August 2020

There has been a growing demand for portfolio management using artificial intelligence (AI). To sustain a competitive advantage for portfolio management, stock market investors require a strategic investment decision that can realize better returns. In this study, we propose a momentum investment strategy that employs a hidden Markov model (HMM) to select stocks in the rising state. We construct an HMM momentum portfolio that includes 890 Korean stocks and analyze the performance of the stocks over the period of January 2000 to December 2018. By identifying states of stocks, sectors, and markets through HMM, our strategy buys shares in the rising state and proceeds with rebalancing after the holding period. The HMM momentum portfolio is determined to earn higher returns than traditional momentum portfolios and to achieve the best performance under the conditions of a short holding period (one week) and a short formation period (one month). In addition, our strategy exhibits competitive performance in market and sector index investment compared with market returns. This study implies that the momentum investment strategy using HMM is useful in the Korean stock market. Based on our HMM momentum strategy, future research can be enriched by applying the HMM to developing a new AI momentum strategy that can be utilized for other portfolios containing various types of financial assets on the global market.
Strong Sustainability in Public Transport Policies: An e-Mobility Bus Fleet Application in Sorrento Peninsula (Italy)
Authors: Cartenì Armando , Henke Ilaria , Molitierno Clorinda , Di Francesco Luigi
Published: August 2020

Sustainability can be defined as the capacity to satisfy current needs without compromising future generations. Sustainable development clashes with the transport sector because of the latter’s high fossil fuels usage, consumption of natural resources and emission of pollutant and greenhouse gases. Electric mobility seems to be one of the best options to achieve both the sustainability goals and the mobility needs. This paper critically analysed weaknesses, strengths and application fields of electric mobility, proposing a real case application of an e-mobility bus fleet in Sorrento peninsula (Italy). The aim and the originality of this research was to propose a public transport design methodology based on a “strong sustainability” policy and applied to a real case study. To be precise, the renewing of the “old” bus fleet with a diesel plug-in hybrid one charged by a photovoltaic system was proposed, aiming to both improve environmental sustainability and perform an investment return for a private operator in managing the transport service. The proposed case study is particularly suitable because the peculiar morphology of the Sorrento peninsula in Italy does not allow other types of public transport services (e.g., rail, metro). Furthermore, this area, rich in UNESCO sites, has always been an international tourist destination because of the environment and landscape. Estimation results show that the new e-mobility bus service will be able to reduce the greenhouse gases emissions up to the 23%, with a financial payback period of 10 years for a private investor.
Effect of Perfluorooctanoic Acid on the Epigenetic and Tight Junction Genes of the Mouse Intestine
Authors: Rashid Faizan , Ahmad Saeed , Irudayaraj Joseph Maria Kumar
Published: August 2020

Perfluorooctanoic acid (PFOA) has been implicated in various toxicities including neurotoxicity, genotoxicity, nephrotoxicity, epigenetic toxicity, immunotoxicity, reproductive toxicity, and hepatotoxicity. However, information on the accumulation of PFOA in the intestine and its toxic effects on intestinal epigenetics and tight junction (TJ) genes is sparse. CD1 mice were dosed with PFOA (1, 5, 10, or 20 mg/kg/day) for 10 days, and its accumulation and induced alterations in the expression of epigenetic and tight junction genes in the small intestine and colon were evaluated using LC–MS and qPCR techniques. PFOA reduced the expression levels of DNA methyltransferases (Dnmt1, Dnmt3a, Dnmt3b) primarily in the small intestine whereas, in the colon, a decrease was observed only at high concentrations. Moreover, ten-eleven translocation genes (Tet2 and Tet3) expression was dysregulated in the small intestine, whereas in the colon Tets remained unaffected. The tight junction genes Claudins (Cldn), Occludin (Ocln), and Tight Junction Protein (Tjp) were also heavily altered in the small intestine. TJs responded differently across the gut, in proportion to PFOA dosing. Our study reveals that PFOA triggers DNA methylation changes and alters the expression of genes essential for maintaining the physical barrier of intestine, with more profound effects in the small intestine compared to the colon.
One of the Triple Poly(A) Signals in the M112-113 Gene Is Important and Sufficient for Stabilizing the M112-113 mRNA and the Replication of Murine Cytomegalovirus
Authors: Cruz-cosme Ruth , Armstrong Najealicka , Tang Qiyi
Published: August 2020

The M112-113 gene is the first early gene of the murine cytomegalovirus (MCMV), and its expression is activated by the immediate-early 3 (IE3) protein during MCMV infection in permissive cells. At its 5′ terminus, a 10-bp motif, upstream of the TATA box of the M112-113 gene, was identified to bind to IE3, and it is necessary for IE3 to activate M112-113 gene expression (Perez KJ et al. 2013 JVI). At the 3′ terminus of the M112-113 gene, three poly(A) signals (PASs) are arranged closely, forming a PAS cluster. We asked whether it is necessary to have the PAS cluster for the M112-113 gene and wondered which PAS is required or important for M112-113 gene expression. In this study, we mutated one, two, or all three PASs in expressing plasmids. Then, we applied bacterial artificial chromosome (BAC) techniques to mutate PASs in viruses. Gene expression and viral replication were analyzed. We found that not all three PASs are needed for M112-113 gene expression. Moreover, we revealed that just one of the three poly(A)s is enough for MCMV replication. However, the deletion of all three PASs did not kill MCMV, although it significantly attenuated viral replication. Finally, an mRNA stability assay was performed and demonstrated that PASs are important to stabilize M112-113 mRNA. Therefore, we conclude that just one of the PASs of the M112-113 gene is sufficient and important for MCMV replication through the stabilization of M112-113 mRNA.
Characterization of the Maternally Derived Antibody Immunity against Rhdv-2 after Administration in Breeding Does of an Inactivated Vaccine
Authors: Baratelli Massimiliano , Molist-Badiola Joan , Puigredon-Fontanet Alba , Pascual Mariam , Boix Oriol , Mora-Igual Francesc Xavier , Woodward Michelle , Lavazza Antonio , Capucci Lorenzo
Published: August 2020

Inactivated strain-specific vaccines have been successfully used to control rabbit haemorrhagic disease (RHD) caused by RHDV-2 in the rabbit industry. It is unknown whether and how vaccination of breeding does contributed to protect the population of young susceptible rabbit kits. The present study investigates whether the immunity against RHDV-2 produced by vaccination of breeding does is transmitted to their progeny and its dynamic once inherited by kits. For this purpose, New Zealand female rabbits of 8–9 weeks of age were allocated into 2 groups of 40 subjects each and bred during 6 reproductive cycles. The first experimental group was vaccinated with a commercially available inactivated vaccine against RHDV-2 whereas the second group was inoculated with PBS. Moreover, the present study was also meant to identify the mechanisms of transmission of that maternal immunity. For this reason, rabbit kits of vaccinated and non-vaccinated breeding does were cross-fostered before milk uptake. The RHDV-2 antibody response was monitored in the blood serum of breeding does and of their kits by competition ELISA (cELISA) and solid-phase ELISA (spELISA). Since it has been clearly demonstrated that cELISA positive rabbits are protected from RHD, we avoided the resorting of the challenge of the kits with RHDV-2. Results showed that RHDV-2 antibodies were inherited by kits up to one year from vaccination of breeding does. Once inherited, the maternally derived antibody response against RHDV-2 lasted at least until 28 days of life. Finally, the study also elucidated that the major contribution to the maternal derived immunity against RHDV-2 in kits was provided during gestation and probably transmitted through transplacental mechanisms although lactation provided a little contribution to it. The present study contributed to elucidate the characteristics of the maternal antibody immunity produced by vaccination and its mechanisms of transmission.
Can Immunization of Hens Provide Oral-Based Therapeutics against COVID-19?
Authors: Pérez de la Lastra José M. , Baca-González Victoria , Asensio-Calavia Patricia , González-Acosta Sergio , Morales-delaNuez Antonio
Published: August 2020

In the current worldwide pandemic situation caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the newest coronavirus disease (COVID-19), therapeutics and prophylactics are urgently needed for a large population. Some of the prophylaxis strategies are based on the development of antibodies targeting viral proteins. IgY antibodies are a type of immunoglobulin present in birds, amphibians, and reptiles. They are usually obtained from egg yolk of hyper-immunized hens and represent a relatively inexpensive source of antibodies. Specific IgY can be produced by immunizing chickens with the target antigen and then purifying from the egg yolk. Chicken IgY has been widely explored as a clinical anti-infective material for prophylaxis, preventive medicine, and therapy of infectious diseases. Administered non-systemically, IgY antibodies are safe and effective drugs. Moreover, passive immunization with avian antibodies could become an effective alternative therapy, as these can be obtained relatively simply, cost-efficiently, and produced on a large scale. Here, we highlight the potential use of polyclonal avian IgY antibodies as an oral prophylactic treatment for respiratory viral diseases, such as COVID-19, for which no vaccine is yet available.
An Absence of Epstein–Barr Virus Reactivation and Associations with Disease Activity in People with Multiple Sclerosis Undergoing Therapeutic Hookworm Vaccination
Authors: Maple Peter A. C. , Gran Bruno , Tanasescu Radu , Pritchard David I. , Constantinescu Cris S.
Published: August 2020

Background: Epstein–Barr virus (EBV) infection is strongly associated with multiple sclerosis (MS). Helminth infection can downregulate antiviral immune responses, potentially protecting against MS, but with a theoretical risk for reactivating latent EBV infection. Objective: To investigate parameters of EBV infection and their relationship with disease activity in people with MS (PwMS) therapeutically vaccinated with Necator americanus (hookworm). Methods: Sequential serum samples from 51 PwMS; 26 therapeutically infected (25 larvae) with N. americanus and 25 controls were tested for EBV virus capsid antigen (VCA) IgG and IgM, EBV nuclear antigen-1 (EBNA-1) IgG, and EBV early antigen (EA) IgG. Disease activity was assessed by periodic MRI. Significance was set at p < 0.05. Results: All PwMS were EBV VCA IgG and EBNA-1 IgG positive, and 35.2% were EBV EA IgG positive. EBV antibody levels were generally stable, and EBV reactivation in PwMS was not demonstrated by significant increases in IgG titre over 12 months. Disease activity was most frequent in PwMS possessing high levels of EBV VCA IgG (>600 units/mL) or EBNA-1 IgG (>150 units/mL); however, there was no association with hookworm treatment. Interpretation: Therapeutic hookworm vaccination was not associated with EBV reactivation. Multiple sclerosis disease activity was associated with high levels of EBV VCA IgG or EBNA-1 IgG.
Development and Sensitivity Analysis of an Empirical Equation for Calculating the Amplitude of Pressure Head Loss of Oscillating Water Flow in Different Types of Pipe
Authors: Zhang Kai , Zhang Baoxu , Zhu Delan
Published: August 2020

Low pressure oscillating water flow can reduce the investment and energy consumption of irrigation. It is also effective in reducing the clogging of an emitter and improving the spraying quality of sprinklers. In order to overcome the problem of the complex process in calculating the amplitude of the pressure head loss of oscillating water flow in different types of pipes, in this study, an empirical equation for the amplitude of the pressure head loss of oscillating water flow in different types of pipe has been developed. Further, validation experiments have been conducted to verify the accuracy of the calculated amplitudes of the pressure head loss by the empirical equation. The results show that average relative error between the measured and the calculated amplitudes of the pressure head loss by the empirical equation is 10.77%. Since the relative errors are small, it is an indication that the amplitudes of the pressure head loss calculated by the empirical equation are accurate. For the empirical equation developed in this study, the sensitivity of the model parameters has been analyzed. The results show that the amplitude of velocity, the internal pipe diameter, and the length of pipe are classified as highly sensitive. The average velocity, the period of oscillating water flow, and the modulus of elasticity of the pipe material are classified as sensitive. The thickness of the pipe wall is classified as medium sensitive. Compared with the calculation models of the existing researches, the empirical equation reduces the number of parameters required to be calculated, by which many complicated calculations are avoided, which greatly improves the computing efficiency. This is conducive to the efficient operation and management of oscillating water flow in irrigation pipe networks and also provides help for the optimal design of irrigation pipe networks.
Establishment of a chart of accounts for management accounting for interorganizational cooperation among agribusiness enterprises
Authors: Khoruzhy Lyudmila , Katkov Yury , Romanova Anastasiya
Published: August 2020

The article, based on theoretical analysis, defines inter-organizational cooperation, inter-organizational management accounting. The algorithm of setting the system of inter-organizational management accounting of agricultural organizations has been developed, advantages of implementation of this type of accounting have been identified, possible difficulties of implementation of such a system have been determined. The concept of the business process is presented, its classification is given. On the example of livestock production, the structure and content of management accounting accounts for use in inter-organizational cooperation are disclosed.
Application of the COSO model of internal control in the system of personnel security of agro-formations
Authors: Khoruzhy  , Katkov Yury , Katkova Ekaterina
Published: August 2020

The article considers methodological and organizational approaches to internal control. The COSO internal control model has been adapted to the human resources security system of agribusiness with key performance indicators. The decomposition of the goals of increasing the net profit of the agricultural organization is given. Key indicators of agroforming activity efficiency are disclosed, as well as criteria of their achievement are identified. Responsible officials for achieving key indicator values are identified. The application of the COSO internal control model in the personnel security system, using key performance indicators, will create a clear and correct methodology for collecting and processing information that meets the strategic and tactical reasons of the agricultural organization.
Effects of Radiation on Protein
Authors: Zhang Rong Ke , Lyu Jia Hua , Li Tao
Published: August 2020

Radiotherapy is one of the most common treatments used for solid tumors. Proteins are important components of all cells and tissues, and the main material basis of life. In the present research, more attention has been paid to the relationship between tumor radiotherapy and glycolipid metabolism, but less attention has been paid to the post-radiation effect of proteins. This article discusses the direct and indirect effects of radiation on proteins. The direct effects include changes in the structure and function of proteins, as well as to their synthesis and degradation, with the most specific effects observed on the post-translational modification of proteins. Indirect effects include changes in the whole-body nutrition level of patients, including the process of protein intake, digestion, absorption and metabolism. This article also addresses the impact of advanced radiotherapy technology, such as proton therapy and heavy ion therapy on proteins, and emphasizes the importance and feasibility of protein-supplying nutritional treatment during the “peri-radiotherapy period”.