bluuebunny/crossref_metadata_2025 huggingface dataset:
Key geological factors controlling oil displacement efficiency of CO2 injection in low-permeability reservoirs
Authors: Wang Zhaosheng , Zeng Lianbo , Yu Jiangtao , Zhang Zhenguo , Yang Siyu , Liu Yuncheng
Published: February 2021

Carbon dioxide (CO2) flooding is an effective method to enhance oil recovery in low-permeability reservoirs. Studying key geological factors controlling oil displacement efficiency is of great significance to the CO2 injection scheme design in low-permeability reservoirs. Focusing on low-permeable H reservoir in Songliao Basin, China, this paper describes the contact and connection of sand bodies, natural fractures and high-permeability zones with core samples, log data and experiment firstly. After that, the impact of interaction of sand body connection, natural fracture and high-permeability zone on oil displacement efficiency is determined by using geological and dynamic data in CO2 injection area. Results indicate that the connection of single sand bodies between injectors and producters wells primarily controls CO2 flooding in low-permeability reservoirs. Furthermore, coupling of sand body connection, natural fractures and high-permeability zones is the key geological factor governing oil displacement efficiency of CO2 injection in low-permeability reservoirs, where well or generally-connected sand bodies can improve the efficiency significantly. Meanwhile, the dominant seepage channels in other directions have no influence on producers, which is beneficial to improve CO2 flooding efficiency.
Effect of Chronic Kidney Disease on Olfactory Function: A Case–Control Study
Authors: Yusuf T. , Raji Y. R. , Daniel A. , Bamidele O. T. , Fasunla A. J. , Lasisi O. A.
Published: February 2021

Background:

Olfactory function of patients with chronic kidney disease (CKD) has been found to be defective, and patients are often unaware of it. This predisposes them to malnutrition with consequence on health recovery and quality of life.

Aim:

To assess the olfactory function and determine the pattern of olfactory dysfunction in patients with CKD attending the University College Hospital, Ibadan.

Materials and Methods:

This was a prospective, hospital-based case–control study of adult patients with CKD. The control group were age- and sex-matched individuals without CKD. Olfactory threshold (OT), odor discrimination (OD), and odor identification (OI) tests were carried out in participants using the “Sniffin Sticks.”

Results:

There were 100 patients with CKD and 100 healthy controls, age ranges between 19 to 86 years (mean ± SD = 46.3 ± 13.9 years) and 20 to 85 years (mean ± SD = 43.4 ± 14.9 years), respectively. There was no statistically significant difference between cases and control gender distribution ( P = .57). The mean olfactory scores were significantly lower among the cases than control, OI 11.2 ± 2.3 and 13.1 ± 1.2 ( P < .001), OD 8.5 ± 2.4 and 10.9 ± 1.5 ( P < .001), OT 6.4 ± 2.5 and 9.6 ± 1.9 ( P < .001), and threshold discrimination and identification 26.0 ± 5.7 and 33.6 ± 3.3 ( P < .001), respectively. Prevalent olfactory dysfunction among patients with CKD was 77% (hyposmia 72%, anosmia 5%), and the control was 16% (all hyposmia; P < .001).

Conclusion:

There was high prevalence of olfactory dysfunction among patients with CKD, and the affectation is more at the central olfactory pathway.
SARS-CoV-2 Nasopharyngeal Swab as a Foreign Body: A Case Report
Authors: Stevens Madelyn N. , Lin George T. , Tittman Sarah M. , Motz Kevin M.
Published: February 2021

The SARS-CoV-2 pandemic response utilizes nasopharyngeal swabbing as a prolific testing method for presence of viral RNA. The depth of the swab to the nasopharynx coupled with breakpoints along the shaft leads to a risk for foreign body retention. Here, we present a case of a nasopharyngeal swab that became a retained foreign body during routine swabbing to test for the SARS-CoV-2 virus. Bedside flexible fiberoptic endoscopy was performed and did not reveal a foreign body in the nasopharynx or larynx. Subsequent computed tomography (CT) scan demonstrated the radiopaque retained foreign body at the distal gastroesophageal junction. The patient remained asymptomatic and did not have any upper airway or gastrointestinal symptoms. This unique case demonstrates a potential risk associated with SARS-CoV-2 nasopharyngeal swab testing and highlights management strategies that serve the patient while adequately protecting health care providers. A standardized approach to evaluation optimally includes bedside flexible endoscopy with appropriate personal protective equipment, prompt airway evaluation if aspiration is suspected, and noncontrasted CT imaging if the known foreign body is not identified via other modalities.
Racializing American Authenticity: Mexican Americans’ Perceptions of the Foreign Other
Authors: Silva Angela J. , Murga Aurelia Lorena
Published: February 2021

Anti-Mexican sentiment in the United States has long plagued the lives of people of Mexican descent. Since their incorporation, Mexican Americans have experienced processes of racialization as second-class citizens while a continuous anti-immigrant climate continues to impact them. This has influenced their use of a white racial frame resulting in their distancing of themselves from perceived foreign-ness. Drawing on 15 in-depth interviews with self-identified Mexican Americans along the U.S.-Mexico border, we find that divisions between the two nations have become embedded in the lived experiences of those residing in the borderland region. The themes raised by our respondents illustrate how Mexican Americans use notions of illegality, belonging to a nation, and the dangerous other to differentiate themselves from foreign-born Mexicans and the ways they address immigration. We argue that Mexican Americans living in a transnational border space navigate their everyday lives as racialized beings, resulting in their search for ways to situate themselves apart from the foreign other. We argue that the larger implications for understanding how Mexican Americans use the white racial frame is significant since their embedded ideas and beliefs are founded upon racist nativist differences that are used to create and support policies that target racialized others.
Extensions after Man: Race, Counter/insurgency and the Futures of Media Theory
Authors: Litwack Michael
Published: February 2021

This article returns to the geopolitical scene and racial logics that provide the underacknowledged conditions of Marshall McLuhan’s Understanding Media and, specifically, its well-known proposition that media should be understood foremost as ‘outerings’ or ‘extensions of man’. Attending to the structuring inheritances of racial slavery and the plantation system in this founding statement of mid-twentieth-century media theory, as well as its debt to the literary and intellectual movement of the Southern Agrarians, I consider how the racializing figure of ‘Man’ conserved by the nascent field of media studies was contemporaneously brought to crisis by black (and) anticolonial freedom struggles. Arguing for the need to reread the career of western media theory through its political vocation in attempting to manage this crisis, the article concludes by turning briefly to a revisionary account of media and exteriority also circulated in 1964: the revolutionary intellectual James Boggs’s ‘The Negro and Cybernation’. Boggs’s writings, which situate emergent forms of computing and cybernation within a longer materialist genealogy of race, capitalism and technology, offer both a proleptic critique of the early disciplinary formation of media theory and a divergent set of coordinates for approaching media technology on the terrain of black political struggle.
Plantar hyperhidrosis associated with primary palmar hyperhidrosis: Outcome following video-assisted thoracoscopic sympathectomy
Authors: Abu Arab Walid Salah , Elhamami Moustafa Mohamed
Published: February 2021

Introduction

Primary palmar hyperhidrosis is an abnormal over-sweating of palms. It is usually associated with plantar hyperhidrosis. Video-assisted thoracoscopic sympathectomy is the treatment of choice for palmar hyperhidrosis; however, it may affect plantar hyperhidrosis.

Objectives

The aim of this study was to evaluate the effect of thoracoscopic sympathectomy on plantar hyperhidrosis.

Methods

This prospective study included patients who presented to the Cardiothoracic Surgery Department with primary palmo-planter hyperhidrosis and received thoracoscopic sympathectomy between January 2014 and December 2018. Preoperatively, patients scored subjectively the degree of palmar and plantar hyperhidrosis on Visual Analogue Scale. Following surgery, scoring was performed at three intervals: 7, 30, and 180 days. Presence of compensatory sweating and its scoring was obtained at the same intervals. Complications and patient satisfaction were recorded.

Results

A total of 518 patients were included. Complication rate, excluding compensatory hyperhidrosis, was 2.7%. Preoperative Visual Analogue Scale score for palmar hyperhidrosis was 9.9 ± 3.8 that following thoracoscopic sympathectomy decreased to 0.041 ± 0.2 on the seventh postoperative day. Further decrease to 0.3 ± 0.16 was noted on the 30th day and 180th day postoperatively. Preoperative Visual Analogue Scale score for plantar hyperhidrosis was 9.54 ± 0.66 that following sympathectomy decreased to 2.27 ± 1.67 on the seventh postoperative day. However, slight insignificant increase was noted to become 2.73 ± 1.65 on the 30th day and 6th month postoperatively. Compensatory hyperhidrosis was recorded in 3.9% of patients at 6th month postoperatively.

Conclusion

Palmar hyperhidrosis is usually associated with plantar hyperhidrosis. Thoracoscopic sympathectomy is an effective and safe treatment for palmar hyperhidrosis. It may completely or partially cure plantar hyperhidrosis.
An unusual penetrating shrapnel in the heart
Authors: Khakural Prabhat , Baral Ravi , Bhattarai Anil , Koirala Bhagawan
Published: February 2021

Penetrating heart trauma is a surgical emergency and can be fatal. However, cardiac penetration occurring due to non-explosive shrapnel is a rare occurrence. We report a case of a 20-year-old man, who sustained a laceration in his left chest, while he was breaking a rock with a chisel and a hammer. He was diagnosed to have an intramyocardial foreign body in his left ventricle. He underwent left ventriculotomy, foreign body localization under fluoroscopic guidance and successful extraction of the shrapnel from the left ventricular cavity.
Risk factors and outcomes of pediatric extracorporeal membrane oxygenation
Authors: Taka Hiroshi , Kotani Yasuhiro , Kuroko Yosuke , Iwadou Susumu , Iwasaki Tatsuo , Kasahara Shingo
Published: February 2021

Background

Congenital heart disease (CHD) is the most common neonatal and pediatric cardiac indication for extracorporeal membrane oxygenation (ECMO). Risk factors of survival and neurologic complication were different in many centers. We sought to evaluate survival and neurological outcome after ECMO in patients with CHD.

Methods

We retrospectively reviewed the medical records of 37 patients (<16 years old) who received ECMO. Indications for ECMO were failure to wean from cardiopulmonary bypass in 18 patients, extracorporeal cardiopulmonary resuscitation (ECPR) in 13 patients, and others in 6 patients. The median cardiopulmonary resuscitation (CPR) duration in ECPR patients was 48 min (interquartile range: 38–53 min). Neurological outcomes were evaluated using the Pediatric Cerebral Performance Category (PCPC) scale one year after hospital discharge.

Results

The median ECMO duration was 160 (91–286) h. Twenty-nine patients (78%) were successfully weaned off ECMO. Overall survival to hospital discharge was 59%. Risk factors of mortality were as follows: ECMO duration >1 week and urine output <1 mL/kg/h in the first 24 h after ECMO induction by multivariable analysis. Of the 22 survivors, 15 (68%) patients had a favorable outcome (PCPC ≤2). Risk factors for unfavorable outcomes (PCPC ≥3) included ECPR as indication and CPR of longer than 40 min.

Conclusions

Longer ECMO duration and lower urine output were associated with increased mortality. Neurologic outcomes were not satisfactory when CPR was required for a longer period before ECMO establishment.
Readiness of individuals with visual impairments for participation in distance education
Authors: Koustriava Eleni
Published: February 2021

Individuals with visual impairments (VI) may face difficulties fitting in a distance education (DE) program mainly because of accessibility issues and a pervading lack of readiness. The main question was which difficulties and, specifically, which specific aspects of participants’ readiness could jeopardize their attendance in a DE program. The aims of this study were to examine the readiness of individuals with VI for participation in DE and the possible relationships between participants’ readiness for participation and their personal characteristics. A 42-item questionnaire has been developed to examine readiness for participation through five sub-scales referring to motivation, skills, self-management, interaction, and access to technological means (including means of assistive technology). The findings revealed a slightly positive degree of readiness as far as participants’ motivation, perception of their skills, and self-management are concerned and an approximate neutral degree of readiness regarding the aspects of interaction and access to technological means in the context of a DE program. The greater the educational level and the frequency of computer usage, the more positive the readiness for participation.
To sext or not to sext. The role of social-cognitive processes in the decision to engage in sexting
Authors: Wilson Claire , van Steen Tommy , Akinyode Christabel , Brodie Zara P. , Scott Graham G.
Published: February 2021

Technology has given rise to online behaviors such as sexting. It is important that we examine predictors of such behavior in order to understand who is more likely to sext and thus inform intervention aimed at sexting awareness. We used the Theory of Planned Behavior (TPB) to examine sexting beliefs and behavior. Participants (n = 418; 70.3% women) completed questionnaires assessing attitudes (instrumental and affective), subjective norms (injunctive and descriptive), control perceptions (self-efficacy and controllability) and intentions toward sexting. Specific sexting beliefs (fun/carefree beliefs, perceived risks and relational expectations) were also measured and sexting behavior reported. Relationship status, instrumental attitude, injunctive norm, descriptive norm and self-efficacy were associated with sexting intentions. Relationship status, intentions and self-efficacy related to sexting behavior. Results provide insight into the social-cognitive factors related to individuals’ sexting behavior and bring us closer to understanding what beliefs predict the behavior.
Phase I study of intraperitoneal bevacizumab for treating refractory malignant ascites
Authors: Kou Furong , Gong Jifang , Li Yan , Li Jian , Zhang Xiaotian , Li Jie , Shen Lin
Published: February 2021

Objective

This prospective, dose-escalation phase I study evaluated the safety and efficacy of intraperitoneal bevacizumab in managing refractory malignant ascites and explored the recommended dose of bevacizumab for further study.

Methods

Patients with refractory malignant ascites were enrolled. Bevacizumab was intraperitoneal administered weekly at an initial dose of 2.5 mg/kg, with dose escalation to 5 and 7.5 mg/kg performed following the standard “3 + 3” rule. The total duration of treatment was 2 or 3 weeks.

Results

Between December 2013 and September 2014, 13 patients (2.5 mg/kg, n = 4; 5 mg/kg, n = 3; 7.5 mg/kg, n = 6) with refractory malignant ascites were enrolled. Bevacizumab was well tolerated, and the most common treatment-related adverse events were abdominal pain (5/13), abdominal distension (2/13), and fatigue (2/13). The dose-limiting toxicity at 7.5 mg/kg was grade 3 bowel obstruction (1/13). The maximum tolerated dose (MTD) was not reached. The overall response and disease control rates were 7.7 and 61.5%, respectively.

Conclusions

Intraperitoneal bevacizumab safe and well tolerated for treating malignant ascites, and the MTD was not reached at doses of 2.5 to 7.5 mg/kg. Intraperitoneal bevacizumab at 7.5 mg/kg weekly is recommended for further study to verify its anti-tumor activity. Trial registration: Clinical Trials NCT01852409.
Case report of new-onset obstructive sleep apnea after carbon monoxide poisoning
Authors: Yang Xiaorong , Xie Min , Tan Lu , Li Taomei , Tang Xiangdong
Published: February 2021

Obstructive sleep apnea (OSA) is characterized by repetitive intermittent oxygen desaturation during sleep. Carbon monoxide poisoning (COP) is the second most common cause of death among non-medicinal poisonings, and oxygen therapy is the current standard of treatment for COP. We herein report a case of a 50-year-old woman diagnosed with severe OSA associated with COP. Both the OSA and COP gradually resolved by automatic continuous positive airway pressure (CPAP) therapy. New OSA symptoms appeared following the development of delayed encephalopathy after acute COP (DEACMP) 3 weeks later. Severe OSA was diagnosed 76 days after COP with an apnea–hypopnea index of 66 events/hour, and CPAP therapy was immediately administered. The patient’s DEACMP symptoms and OSA both improved with CPAP therapy (her apnea–hypopnea index decreased to 32.4 and 16.5 events/hour at 161 and 204 days after COP, respectively). To our knowledge, this is the first case report of OSA caused by COP based on the occurrence and disappearance of OSA symptoms and laboratory findings associated with the emergence and improvement of DEACMP.
Two hundred and forty-eight cases of visual snow: A review of potential inciting events and contributing comorbidities
Authors: Mehta Dev G , Garza Ivan , Robertson Carrie E
Published: February 2021

Objective

To review characteristics and outcomes of all cases of visual snow seen at our institution, with attention to possible triggering events or comorbidities.

Methods

This is a retrospective case series of patients seen at our tertiary care center from January 1994 to January 2020. Charts were reviewed if they contained the term “visual snow”.

Results

Of the 449 charts reviewed, 248 patients described seeing visual snow in part or all of their vision. Thirty-eight reported transient visual snow as their typical migraine aura. Of the remaining 210 patients, 89 were reported to have either an inciting event or contributing comorbidity for their visual snow symptoms, including: Post-concussion (n = 15), dramatic change in migraine or aura (n = 14), post-infection (n = 13), hallucinogen persisting perception disorder (n = 10), ocular abnormalities (n = 7), idiopathic intracranial hypertension (n = 4), neoplastic (n = 1), and posterior cortical atrophy (n = 1). Some patients had partial improvement with benzodiazepines (n = 6), lamotrigine (n = 5), topiramate (n = 3) and acetazolamide (n = 3). Presenting characteristics were similar, but patients with visual snow attributed to an inciting event or contributing comorbidity were more likely to have some improvement in their symptoms by last follow-up compared to spontaneous visual snow ( p < .001).

Conclusions

Though most cases of visual snow are spontaneous, potential secondary causes should be recognized by clinicians. Patients who develop visual snow after an inciting event or related to an underlying comorbidity may have a better prognosis than those in whom it develops spontaneously. In select cases, treatment of the suspected underlying cause may significantly alleviate the otherwise typical intractable visual disturbances associated with visual snow.
Clinical Outcomes, Structure, and Function Improve With Both Heavy and Moderate Loads in the Treatment of Patellar Tendinopathy: A Randomized Clinical Trial
Authors: Agergaard Anne-Sofie , Svensson Rene B. , Malmgaard-Clausen Nikolaj M. , Couppé Christian , Hjortshoej Mikkel H. , Doessing Simon , Kjaer Michael , Magnusson S. Peter
Published: February 2021

Background:

Loading interventions have become a predominant treatment strategy for tendinopathy, and positive clinical outcomes and tendon tissue responses may depend on the exercise dose and load magnitude.

Purpose/Hypothesis:

The purpose was to investigate if the load magnitude influenced the effect of a 12-week loading intervention for patellar tendinopathy in the short term (12 weeks) and long term (52 weeks). We hypothesized that a greater load magnitude of 90% of 1 repetition maximum (RM) would yield a more positive clinical outcome, tendon structure, and tendon function compared with a lower load magnitude of 55% of 1 RM when the total exercise volume was kept equal in both groups.

Study Design:

Randomized clinical trial; Level of evidence, 1.

Methods:

A total of 44 adult participants with chronic patellar tendinopathy were included and randomized to undergo moderate slow resistance (MSR group; 55% of 1 RM) or heavy slow resistance (HSR group; 90% of 1 RM). Function and symptoms (Victorian Institute of Sport Assessment–Patella questionnaire [VISA-P]), tendon pain during activity (numeric rating scale [NRS]), and ultrasound findings (tendon vascularization and swelling) were assessed before the intervention, at 6 and 12 weeks during the intervention, and at 52 weeks from baseline. Tendon function (functional tests) and tendon structure (ultrasound and magnetic resonance imaging) were investigated before and after the intervention period.

Results:

The HSR and MSR interventions both yielded significant clinical improvements in the VISA-P score (mean ± SEM) (HSR: 0 weeks, 58.8 ± 4.3; 12 weeks, 70.5 ± 4.4; 52 weeks, 79.7 ± 4.6) (MSR: 0 weeks, 59.9 ± 2.5; 12 weeks, 72.5 ± 2.9; 52 weeks, 82.6 ± 2.5), NRS score for running, NRS score for squats, NRS score for preferred sport, single-leg decline squat, and patient satisfaction after 12 weeks, and these were maintained after 52 weeks. HSR loading was not superior to MSR loading for any of the measured clinical outcomes. Similarly, there were no differences in functional (strength and jumping ability) or structural (tendon thickness, power Doppler area, and cross-sectional area) improvements between the groups undergoing HSR and MSR loading.

Conclusion:

There was no superior effect of exercising with a high load magnitude (HSR) compared with a moderate load magnitude (MSR) for the clinical outcome, tendon structure, or tendon function in the treatment of patellar tendinopathy in the short term. Both HSR and MSR showed equally good, continued improvements in outcomes in the long term but did not reach normal values for healthy tendons.

Registration:

NCT03096067 (ClinicalTrials.gov identifier)
Coronal Lateral Collateral Ligament Sign: A Novel Magnetic Resonance Imaging Sign for Identifying Anterior Cruciate Ligament–Deficient Knees in Adolescents and Summarizing the Extent of Anterior Tibial Translation and Femorotibial Internal Rotation
Authors: Mitchell Brendon C. , Siow Matthew Y. , Bastrom Tracey , Bomar James D. , Pennock Andrew T. , Parvaresh Kevin , Edmonds Eric W.
Published: February 2021

Background:

Incompetence of the anterior cruciate ligament (ACL) confers knee laxity in the sagittal and axial planes that is measurable with clinical examination and diagnostic imaging.

Hypothesis:

An ACL-deficient knee will produce a more vertical orientation of the lateral collateral ligament (LCL), allowing for the entire length of the LCL to be visualized on a single coronal slice (coronal LCL sign) on magnetic resonance imaging.

Study Design:

Cohort study (diagnosis); Level of evidence, 3.

Methods:

Charts were retrospectively reviewed from April 2009 to December 2017 for all patients treated with ACL reconstruction (constituting the ACL-deficient cohort). A control cohort was separately identified consisting of patients with a normal ACL and no pathology involving the collateral ligaments or posterior cruciate ligament. Patients were excluded for follow-up <2 years, incomplete imaging, and age >19 years. Tibial translation and femorotibial rotation were measured on magnetic resonance images, and posterior tibial slope was measured on a lateral radiograph of the knee. Imaging was reviewed for the presence of the coronal LCL sign.

Results:

The 153 patients included in the ACL-deficient cohort had significantly greater displacement than the 70 control patients regarding anterior translation (5.8 vs 0.3 mm, respectively; P < .001) and internal rotation (5.2° vs −2.4°, P < .001). Posterior tibial slope was not significantly different. The coronal LCL sign was present in a greater percentage of ACL-deficient knees than intact ACL controls (68.6% vs 18.6%, P < .001). The presence of the coronal LCL sign was associated with greater anterior tibial translation (7.2 vs 0.2 mm, P < .001) and internal tibial rotation (7.5° vs –2.4°, P = .074) but not posterior tibial slope (7.9° vs 7.9°, P = .973) as compared with its absence. Multivariate analysis revealed that the coronal LCL sign was significantly associated with an ACL tear (odds ratio, 12.8; P < .001).

Conclusion:

Our study provides further evidence that there is significantly more anterior translation and internal rotation of the tibia in the ACL-deficient knee and proves our hypothesis that the coronal LCL sign correlates with the presence of an ACL tear. This coronal LCL sign may be of utility for identifying ACL tears and anticipating the extent of axial and sagittal deformity.
Optimal parameters of abrasive flow finishing for hip joint implants
Authors: Choopani Yahya , Khajehzadeh Mohsen , Razfar Mohammad Reza
Published: February 2021

Total hip arthroplasty (THA) is one of the most well-known orthopedic surgeries in the world which involves the substitution of the natural hip joint by prostheses. In this process, the surface roughness of the femoral head plays a pivotal role in the performance of hip joint implants. In this regard, the nano-finishing of the femoral head of the hip joint implants to achieve a uniform surface roughness with the lowest standard deviation is a major challenge in the conventional and advanced finishing processes. In the present study, the inverse replica fixture technique was used for automatic finishing in the abrasive flow finishing (AFF) process. For this aim, an experimental setup of the AFF process was designed and fabricated. After the tests, experimental data were modeled and optimized to achieve the minimum surface roughness in the ASTM F138 (SS 316L) femoral head of the hip joint through the use of response surface methodology (RSM). The results confirmed uniform surface roughness up to the range of 0.0203 µm with a minimum standard deviation of 0.00224 for the femoral head. Moreover, the spherical shape deviation of the femoral head was achieved in the range of 7 µm. The RSM results showed a 99.71% improvement in the femoral head surface roughness (0.0007) µm under the optimized condition involving the extrusion pressure of 9.10 MPa, the number of finishing cycles of 95, and SiC abrasive mesh number of 1000.
Now You Hear Me, Later You Don’t: The Immediacy of Linguistic Computation and the Representation of Speech
Authors: Caplan Spencer , Hafri Alon , Trueswell John C.
Published: February 2021

What happens to an acoustic signal after it enters the mind of a listener? Previous work has demonstrated that listeners maintain intermediate representations over time. However, the internal structure of such representations—be they the acoustic-phonetic signal or more general information about the probability of possible categories—remains underspecified. We present two experiments using a novel speaker-adaptation paradigm aimed at uncovering the format of speech representations. We exposed adult listeners ( N = 297) to a speaker whose utterances contained acoustically ambiguous information concerning phones (and thus words), and we manipulated the temporal availability of disambiguating cues via visually presented text (presented before or after each utterance). Results from a traditional phoneme-categorization task showed that listeners adapted to a modified acoustic distribution when disambiguating text was provided before but not after the audio. These results support the position that speech representations consist of activation over categories and are inconsistent with direct maintenance of the acoustic-phonetic signal.
An integrative approach to estimating productivity in past societies using Seshat: Global History Databank
Authors: Turchin Peter , Currie Thomas , Collins Christina , Levine Jill , Oyebamiji Oluwole , Edwards Neil R , Holden Philip B , Hoyer Daniel , Feeney Kevin , François Pieter , Whitehouse Harvey
Published: February 2021

This article reports the results of a collaborative effort to estimate agricultural productivities in past societies using Seshat: Global History Databank. We focus on 30 Natural Geographic Areas (NGAs) distributed over 10 major world regions (Europe, Africa, Southwest Asia, South Asia, Southeast Asia, East Asia, Central Eurasia, North America, South America, and Oceania). The conceptual framework that we use to obtain these estimates combines the influences of the production technologies (and how they change with time), climate change, and effects of artificial selection into a Relative Yield Coefficient, indicating how agricultural productivity changed over time in each NGA between the Neolithic and the 20th century. We then use estimates of historical yield in each NGA to translate the Relative Yield Coefficient into an Estimated Yield (tonnes per hectare per year) trajectory. We tested the proposed methodology in two ways. For eight NGAs, in which we had more than one historical yield estimate, we used the earliest estimate to anchor the trajectory and compared the ensuing trajectory to the remaining estimates. We also compared the end points of the estimated NGA trajectories to the earliest (the 1960s decade) FAO data on crop productivities in the modern countries encompassing Seshat NGAs. We discuss the benefits of this methodology over previous efforts to estimate agricultural productivities in world history.
Self-Cultivation as the Basis of Person Making: A Confucian Perspective Illustrated by a Case Study of Zeng Guofan
Authors: Yongli Liu , Yiping Liu
Published: February 2021

As a model of self-cultivation in accordance with the Confucian theory of Xinxing-Gongfu (心性-功夫论), Zeng Guofan (1811–1872), a well-renowned Confucian scholar and successful minister of the Qing Dynasty (1636–1912) in China, is a prime exemplar of ‘self-cultivation as the basis of person-making’ (修身为本). Considerable historical data proves he consciously strove to perfect himself in a systemic way. By examining his Diaries, Family Letters, and Reading Records, this study identifies that he had three interrelated practices of self-cultivation: (a) The establishment of the moral self. With the proposition that ‘if you are not a sage, you are a beast’, Zeng advocated improving one’s character through self-reflection, self-blame, self-discipline and self-encouragement. (b) Individual moral practice and the learning of moral knowledge. Zeng believed that one could strengthen one’s moral cultivation by keeping a diary, meditating, reading Confucian classics, extracting and reciting famous quotes from former sages, writing essays and practicing calligraphy. (c) The construction of family and cultural community. Zeng’s experience provides illustration that cultural communities can be constructed through the process of a father delivering life experiences to his children, friends and colleagues, and that self-criticism can be used in the service of self-enhancement in Confucian psychology.
Corruption Measurements: Caught Between Conceptualizing the Phenomenon and Promoting New Governance Agenda?
Authors: Perumal Kannan
Published: February 2021

The work ‘Corruption Measurements: Caught Between Conceptualizing the Phenomenon and Promoting New Governance Agenda?’ is a qualitative study based on reviewing the literature available on the subject. It starts with the introduction that explains the evolution of the idea of measuring corruption, its relevance to governance and associated theoretical issues. The topic, ‘Evolution of Corruption Measurements’ gives an overview about different corruption indices. While the topic ‘Challenges to Corruption Measurements’ briefly introduces the challenges faced by corruption measurements, the topics ‘Conceptualizing Corruption’ and ‘Methodological Issues’ give insight into the contentions faced by corruption measurements from different theoretical perspectives. Also, explained in these sections are how the corruption measurements have conceptualized corruption over the period of three decades; and how do they keep evolving their methods in order to become more relevant in policy advocacy. Issues associated with data aggregation also are explained in-depth in this work. This work demonstrates that though continuous methodological evolution and empirical research have helped corruption measurements to improve their acceptance level, the gap that exist between corruption control framework and practice will remain a challenge to address in future if corruption measurements do not genuinely account the contextual realities.
Entrepreneurial Competencies and Microenterprises Sustainability
Authors: Fazal Syed Ali , Al Mamun Abdullah , Ahmad Ghazali Bin , Al-Shami Sayed Samer Ali
Published: February 2021

In this article, we report a study undertaken to measure the effects of selected competency dimensions on the microenterprise sustainability in Malaysia under the premise of the resource-based view (RBV). We adopted a cross sectional approach. Quantitative data were collected from 300 micro-entrepreneurs in Malaysia who were selected using a random sampling technique. Commitment, conceptual, opportunity recognizing, organizing and relationship competencies had significant positive impacts on microenterprise sustainability. The empirical evidence forwarded in this article extends the current micro-entrepreneurship literature in Malaysia and recommends that relevant policy measures need to be enforced for improving microenterprise sustainability based on key entrepreneurial competencies.
Impact of COVID-19 on FDIs, Remittances and Foreign Aids: A Case Study of Nepal
Authors: Bhattarai Gaurav , Subedi Binita
Published: February 2021

The global economy has been severely paralysed, owing to the unprecedented crisis triggered by the COVID-19 pandemic, and different studies have indicated that the crisis is relatively more maleficent to the lower-income and middle-income economies. Methodologically, this study relied on the review and analysis of the grey literature, media reporting and data published by the Asian Development Bank, United Nations Conference on Trade and Development (UNCTAD), United Nations (UN), World Bank, International Monetary Fund (IMF) among others. The article begins by describing the impact of the pandemic on low-income and middle-income countries, and it discusses how they have responded to the crisis. While discussions have surfaced regarding whether COVID-19 will reverse the process of globalization, what will be its impact on the low-income country like Nepal? The study also highlights that with foreign direct investments speculated to shrink and foreign assistance and remittance taking a hit, how is Nepal struggling to keep its economy afloat? Analysing the new budget that the government unveiled in 2020, this study concludes with a note that instead of effectively implementing the plans and policies directed by the budget, Nepal is unnecessarily engaged in political mess and is needlessly being dragged into the geopolitical complications.
A phenomenological constitutive model for one-dimensional shape memory alloys based on artificial neural network
Authors: Wang Fan , Wang Lin-Xiang
Published: February 2021

Shape Memory Alloys (SMA) have become a material with great application prospects because of their unique characteristics and superior properties. A phenomenological constitutive model for SMA is constructed in the current paper. The proposed constitutive model is based on the phenomena observed in the experiment, and Artificial Neural Networks (ANN) are used to simulate part of the characteristics of SMA. The parameter identification method is also proposed, where Back-Propagation (BP) algorithm and the nonlinear optimisation algorithm are used at the same time. The numerical experiment has been carried out, which can well capture the constitutive relationship curve obtained from uniaxial tension and compression experiments of SMA, thus the model can be verified. The model can also describe the phase transformation characteristics of SMA well.
Hysteresis modeling and feedforward compensation of a flexible structure actuated by macro fiber composites using bias bipolar Prandtl-Ishlinskii model
Authors: Xu Jinqiu , Lou Junqiang , Yang Yiling , Chen Tehuan , Chen Hairong , Cui Yuguo
Published: February 2021

As a novel fiber-based piezoelectric composite material, macro fiber composites (MFC) affords notable advantages of good flexibility, high deformability, and large actuation ability. However, the intrinsic hysteresis behavior of the MFC decreases the positioning precision and performance of the flexible structure actuated by MFC actuators. A bias bipolar Prandtl-Ishlinskii (BBPI) model is presented to describe the bias bipolar hysteresis nonlinearity of a MFC-actuated flexible cantilever. The BBPI hysteresis model is composed of two parts: a superposition of the weighted play operators of the classical Prandtl-Ishlinskii (PI) model is employed to characterize the symmetric hysteresis. And a superposition of the weighted dead-zone operators is cascaded to deal with the bias bipolar behavior. Experimental identification results demonstrate that the presented BBPI model exhibits better modeling performance than the classical PI model. A feedforward compensation strategy based on the inverse BBPI hysteresis model is proposed. Experiments on trajectories tracking subject to a triangular wave, sinusoidal wave, and triangular wave with random amplitudes are carried out. Experimental results demonstrate the feasibility and effectiveness of the proposed BBPI model and the inverse feedforward compensator.
“I put diabetes on the shelf”: African-American Women’s Perceptions of Risk for Diabetes Complications
Authors: Ochieng Judith Muhonja , Crist Janice D.
Published: February 2021

The purpose of this study was to describe the perceptions of African American (AA) women with Type 2 diabetes mellitus (T2DM) about developing diabetes mellitus (DM) complications and explore how their perceived risk influenced DM self-management. Ten ( N = 10) AA women participated in the qualitative description study through semi-structured interviews. Thematic analysis informed by the Health Belief Model and Risk Perception Conceptual Model revealed the perceived probability of DM complications by AA women with T2DM and how they made judgments regarding the seriousness, extent, or severity of complications. Those with high levels of DM knowledge perceived themselves at high risk of developing DM complications and those with low DM knowledge perceived themselves at low risk of DM complications. Risk perceptions and health literacy also influenced DM self-management behaviors.
Pathologic Determination of Multifocality in pT1a1 Squamous Cell Carcinoma of the Cervix: A Retrospective Analysis
Authors: Hu Jingjing , Rawish Kojo R. , Leivo Mariah , Adams Dennis , Zare Somaye Y. , Fadare Oluwole
Published: February 2021

When more than one focus of stromal invasion is present in a superficially invasive cervical squamous cell carcinoma (SCC), determination of the tumoral lateral extent/horizontal extension, and hence tumor-nodes-metastases (TNM) staging, can be problematic. In recent years, a diagnostic approach to distinguish multifocal pT1a1 from pT1b cases has gained increased attention. These criteria call for classifying SCC as multifocal when invasive foci are separated by blocks of uninvolved cervical tissues, and/or are located on separated cervical lips in a tumor that is discontinuous, and/or are situated far apart (≥2 mm) from each other. In this study, we assess our experience with multifocal stage pT1a1 cervical SCC that was retrospectively classified as such using these criteria. Slides from the loop electrosurgical excision or conization specimens, comprising 212 pT1a1, 173 pT1a2, and 206 pT1b cases, were reviewed. Twenty-four (11%) of the 212 pT1a1 cases were classified as multifocal after review. The 24 multifocal pT1a1 cases were compared with the 188 unifocal pT1a1 cases regarding a variety of clinicopathologic parameters. Notably, these 2 groups showed no significant differences regarding all parameters that were evaluated, including patient age, recurrence rate, primary tumoral features in the primary excision specimen (rate of positive margins, median depth of stromal invasion, frequency of lymphovascular invasion), and frequency of residual disease in additional excisions. In summary, we demonstrate comparably favorable patient outcomes in both unifocal and multifocal cases of pT1a1 SCC of the cervix, and, accordingly, we conclusively affirm the validity of the aforementioned criteria for establishing multifocality.
Acute Disseminated Encephalomyelitis (ADEM): A Demyelinating Disease with Specific Morphological Features
Authors: Cordier Fleur , Velthof Lars , Creytens David , Van Dorpe Jo
Published: February 2021

Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated inflammatory and demyelinating disorder of the central nervous system. Its characteristic perivenular demyelination and inflammation aid in the differential diagnosis with other inflammatory demyelinating diseases. Here, we present a clinical case of ADEM, summarize its histological hallmarks, and discuss pitfalls concerning the most important neuropathological differential diagnoses.
Description of the role of pharmacist independent double checks during cognitive order verification of outpatient parenteral anti-cancer therapy
Authors: Booth Jennifer P , Kennerly-Shah Julie M , Hartman Amber D
Published: February 2021

Introduction

To describe pharmacist interventions as a result of an independent double check during cognitive order verification of outpatient parenteral anti-cancer therapy.

Methods

A single-center, retrospective analysis of all individual orders for outpatient, parenteral anti-cancer agents within a hematology/oncology infusion center during a 30 day period was conducted. The primary endpoint was error identification rates during first and second verification. Secondary endpoints included the type, frequency, and severity of errors identified during second verification using a modified National Coordinating Council for Medication Error Reporting and Prevention Index.

Results

A total of 1970 anti-cancer parenteral orders were screened, from which 1645 received an independent double check and were included. The number of errors identified during first and second verification were 30 (1.8%) and 10 (0.6%) respectively; second verification resulted in a 33.3% increase in corrected errors. The 10 errors identified during second verification included: four rate transcriptions to optimize pump interoperability, three rate and/or volume modifications, two dosage adjustments, and one treatment deferral due to toxicity. The severity was classified as Category A for four (40%), Category C for three (30%), and Category D for three (30%) errors. This correlated to a low capacity for harm for seven (70%) and a serious capacity for three (30%) errors.

Conclusions

Second verification of outpatient, parenteral anti-cancer medication orders resulted in a 33.3% increase in corrected errors. Three errors detected during second verification were determined to have a serious capacity for harm, supporting the value of independent double checks during pharmacist cognitive order verification.
A Cross-National Service Strategy to Manage Product Returns: E-Tailers’ Return Policies and the Legitimating Role of the Institutional Environment
Authors: Gäthke Jana , Gelbrich Katja , Chen Shan
Published: February 2021

Global e-tailers face product returns from across the world, but research on service strategies for successful product return handling in culturally diverse markets is virtually nonexistent. This study examines the drivers of product return–related customer behavior across Western and Eastern cultures. Using a multimethod approach comprising two surveys and one experiment, results from the major Western (United States) and Eastern (China) retail markets show varying patterns for product return behavior and a uniform pattern for repurchase intention. Specifically, return policies that imply high effort restrictiveness decrease product returns in Western but not Eastern cultures, while the perceived customer-oriented institutional environment increases product returns in Eastern but not Western cultures. For repurchase intention, we find that effort restrictiveness in both cultures decreases repurchase intention, while the perceived customer-oriented institutional environment increases repurchase intention. We also find self-interest and legitimacy as the mechanisms responsible for the effect of perceived institutional environment, an important context variable in international marketing that has been neglected in the product return context. These findings enhance our understanding of product returns in different cultural environments and offer valuable insights for an adequate service strategy in product return management by global e-tailers.
Therapeutic Effectiveness of AxioBionics Wearable Therapy Pain Management System in Patients with Chronic Lower Back Pain
Authors: Muccio Philip , Schueller Josh , van Emde Boas Miriam , Howe Norm , Dabrowski Edward , Durrant David
Published: February 2021

Chronic lower back pain is one of the most common medical conditions leading to a significant decrease in quality of life. This study retrospectively analyzed whether the AxioBionics Wearable Therapy Pain Management (WTPM) System, a customized and wearable electrical stimulation device, alleviated chronic lower back pain, and improved muscular function. This study assessed self-reported pain levels using the visual analog scale before and during the use of the AxioBionics WTPM System when performing normal activities such as sitting, standing, and walking (n = 69). Results showed that both at-rest and activity-related pain were significantly reduced during treatment with the AxioBionics WTPM System (% reduction in pain: 64% and 60%, respectively; P < .05). Thus, this study suggests that the AxioBionics WTPM System is efficacious in treating chronic lower back pain even when other therapies have failed to sufficiently decrease reported pain levels.