bluuebunny/crossref_metadata_2025 huggingface dataset:
Sémio-significativité du paradigme "race" et (a)perceptions de la croix dans La Croix du Sud de Joseph Ngoué
Authors: EYENGA ONANA Pierre Suzanne
Published: April 2022

Quel sens attribue Joseph Ngoué au paradigme race tant ce dernier entretient un commerce fructueux avec la symbolique de la croix dans le drame scénarisé ? En trois parties adossées à la sémiologie théâtrale de Patrice Pavis, la présente étude entend tour à tour disséquer le sens que revêt l’allégorie de l’ombre et de la lumière dans le tracé du destin des personnages cibles du texte. Ensuite, questionner l’esthétique à l’œuvre dans la pièce avant de montrer comment le double drame y noué porte le stigmate d’un plaidoyer fécond : reconstruire une humanité sacrifiée à l’autel des égoïsmes racistes inopérants.
De la pensée à la violence verbale
Authors: ATOUBA Jean Pierre
Published: April 2022

Le présent article s’intéresse à l’incidence de la violence verbale sur le personnage. En se fondant sur la sémiotique discursive, il montre comment la parole constitue un outil d’exclusion dans l’œuvre circonscrite et relève la façon dont son auteure projette sur scène des personnages en situations discursives. Destination Biafra regorge de ces espaces troubles où le personnage se retrouve en situation de dysphorie avec son environnement. Cette dysharmonie se justifie par la quête d’un mieux-être, l’envie de concrétiser certains fantasmes et le besoin d’assouvir des velléités utopiques. Ponctué de propos injurieux méprisants et blessants, le discours de l’être anthropomorphe vise bien souvent la mise à l’écart ou le rejet systématique de l’autre. Buchi Emecheta crée-t-elle autour de ses protagonistes des espaces favorables au dialogue et à la tolérance ou alors les expose-t-elle aux propos attentatoires de leurs semblables ? Quelle rhétorique (poétique d’inclusion ou d’exclusion) utilisent les acteurs anthropomorphes au sein de leurs tissus relationnels ? L’analyse des discours invectiveurs et la fréquence de leur utilisation amènent à observer que les affronts verbaux constituent des poisons rhétoriques qui visent à réduire l’être mal apprécié au silence.
Intersémioticité et narrativité dans le roman contemporain
Authors: NOMO FOUDA Floribert
Published: April 2022

La présente étude, qui s’inscrit dans le domaine de la narratologie, interroge la contribution des codes sémiotiques exogènes à l’expression de la narrativité du récit romanesque contemporain, en l’occurrence L’Enfant de la révolte muette de Camille Nkoa Atenga. Ce dernier intègre à sa texture des médias tels que les proverbes, la légende, le texte biblique, le téléphone, la danse et la musique. Références à l’altérité par rapport au code sémiotique romanesque, ces systèmes de signes saturent et irradient le schéma narratif, dans sa paradigmatique et sa syntagmatique. Il en résulte que l’intersémioticité est un outil fécond d’exégèse narrative du récit romanesque contemporain.
Направления развития инновационно-инертных регионов
Authors: Павлова Татьяна Сергеевна
Published: April 2022

Цель: работа посвящена системному исследованию проблем управления инновационным развитием регионов на основе применения сценарного подхода, обоснования направления развития инновационно-инертных регионов РФ. Обсуждение: сценарии управления развитием инновационной среды региона. Стратегические направления инновационного развития территорий с целью повышения инновационного потенциала регионов и их инновационной активности. Результаты: в статье обоснована точка зрения авторов на управление развитием инновационно-инертных регионов с точки зрения сценарного подхода. Обоснованы направления развития инновационно-инертных регионов Северо-Кавказского федерального округа, к которым относятся Карачаево-Черкессия, Дагестан, Кабардино-Балкария, Чечня, Ингушетия.
Эффект кражи бизнеса. О равновесном и оптимальном числе фирм в эндогенной олигополии
Authors: Макольская Яна Сергеевна , Филатов Александр Юрьевич
Published: April 2022

Цель: статья посвящена сопоставлению равновесного и общественно эффективного числа фирм на олигопольном рынке со свободным входом, в том числе выявлению формальных условий, при которых ограничение избыточной конкуренции приводит к росту общественного благосостояния и к его падению. Обсуждение: равновесное число фирм в эндогенной олигополии находится в условии нулевой прибыли. Как было доказано ранее, при выполнении ряда очевидных и, на первый взгляд, всегда выполняющихся предположений равновесное число фирм является избыточным. Причиной этого является так называемый «эффект кражи бизнеса», связанный с тем, что входящие на рынок новички вынуждают укоренившиеся фирмы сокращать производство. Результаты: авторами показано, что вопреки устоявшемуся мнению эффект кражи бизнеса не наблюдается для многих используемых на практике спецификаций модели, в т.ч. для постоянно эластичного спроса. Это означает противоположные выводы и необходимость государственного стимулирования входа на рынок по причинам, отличным от стимулирования разнообразия и конкуренции. Также в работе изучается проблема целочисленности и вносимые ею особенности.
Переход «учеба — работа» студентов и выпускников программ среднего профессионального образования
Authors: Дудырев Федор , Рожкова Ксения , Романова Ольга , Травкин Павел
Published: April 2022

В информационном бюллетене анализируется текущее состояние перехода «учеба – работа» студентов и выпускников системы среднего профессионального образования, исследуются их карьерные и образовательные планы. Рассмотрены аспекты трудоустройства выпускников организаций СПО, в частности следующие вопросы: совмещение студентами учебы и работы, соответствие специализации выполняемой работе, способы поиска работы, финансовые ожидания, самооценка студентами и выпускниками своих профессиональных знаний и навыков и др.
[RETRACTED] TrimLab Keto Gummies - Reduce Your Body Fat Or A Real Weight Loss Product? v1
Authors: Keto Gummies Reviews TrimLab
Published: April 2022

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TrimLab Keto Gummies Reviews
[RETRACTED] Vermont Pure Hemp CBD Gummies Reviews: (Works Or Hoax)Alleviating The Symptoms of Depression and Anxiety! v1
Authors: not provided lilianspooner
Published: April 2022

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Vermont CBD Gummies
[RETRACTED] Second Century CBD Gummies Reviews - SCAM ALERT! Peruse The Real Fact Before Buy? v1
Authors: Century CBD Gummies Second
Published: April 2022

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Second Century CBD Gummies
[RETRACTED] Lisa Laflamme CBD Gummies Canada RESULT REVIEWS, 100% SAFE & RISK FREE! v1
Authors: not provided marthaboosh
Published: April 2022

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Assuming you're experiencing joint agony that even medications can't give recuperation thenLisa Laflamme CBD Gummies are the arrangement that you expect to enjoy your life. This item has the affinity to furnish fundamental supplements with key fixing is CBD. This item has made an unrest in the clinical field on the grounds that the quantity of advantages that this single item gives isn't quantities of medication ready to do as such. It is an exceptionally powerful recipe to take out ongoing torment, nervousness, and sadness inside a short span by focusing on the main driver.
[RETRACTED] K1 Keto Life Reviews - Is It Legitimate Or Scam Pills? v1
Authors: Life Keto Reviews Trim
Published: April 2022

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K1 Keto Life Reviews - Is It Legitimate Or Scam Pills?
[RETRACTED] Visiprime - SCAM ALERT? READ MY PERSONAL EXPERIENCE! v1
Authors: H H
Published: April 2022

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Visiprime:No one will handily encounter the evil impacts of weight gain and weariness. This is the consequence of the manner in which we experience nowadays.
[RETRACTED] Lisa Laflamme CBD Gummies - The Real Reason Everyone Is Buying! v1
Authors: H H
Published: April 2022

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Lisa Laflamme CBD Gummiesconstipation. The lactose and vitamin D in the milk help to enhance calcium absorption.
Karanlık Sosyal Medya ve Sosyal Medyanın Karanlık Yüzü: Kavramlar, Araştırmalar ve Stratejiler
Authors: ERDOĞAN İlker
Published: April 2022

Sosyal medya araştırmalarının pek çoğu, sosyal medyanın hem bireylere (tüketicilere) hem de şirketlere sağladığı avantajlardan bahsederken sosyal medyanın aydınlık yüzüne odaklanmaktadır. Ancak, sosyal medyanın sağladığı sayısız avantaja rağmen, sosyal medyanın karanlık yüzüne odaklanan sosyal medya araştırmalarının sayısı giderek artmaktadır. Türkçe alanyazında ise hem “karanlık sosyal medya” kavramına hem de sosyal medyanın karanlık yüzüne odaklanan çok az sayıda örnek olay araştırması ya da ampirik araştırma bulunmaktadır. Bu bağlamda, Türkiye’de akademik bir boşluk söz konusudur. Bu makalenin amacı, “karanlık sosyal medya” ve sosyal medyanın karanlık yüzü ile ilgili uluslararası alanyazın taraması yapmaktır. Bu amaçla, makale, “karanlık sosyal medya”ya ilişkin kavramsal yaklaşımlara odaklanmakta ve sosyal medyanın işlevselliğine (paylaşım, mevcudiyet, sohbetler, kimlik, ilişkiler, gruplar ve itibar) dayanan kavramsal ve teorik bir çerçeveyi irdelemektedir. Makalede, sosyal medyanın karanlık yüzüne odaklanan araştırmaların bulgularına yer verilmekte ve sosyal medyanın neden olduğu tahribat gözler önüne serilmektedir. Ayrıca, makalede hem bu araştırmaların geleceğine ışık tutan önermeler hem de sosyal medyadan kaynaklanan riskleri azaltmak için geliştirilmiş stratejiler vurgulanmaktadır.
Ability of the Saccharomyces cerevisiae Y904 to tolerate and adapt to high concentrations of selenium
Authors: Amorim Mota Layna , Maria da Silva Ana Paula , Alberto da Silva Eric , Maria Ferreira Lima Leite Gabriela , Perez Calegari Rubens , Sampaio Baptista Antonio
Published: April 2022

The alcoholic fermentation industry generates a large surplus of yeasts, which, in turn, have the ability to bioaccumulate minerals and enable their bioavailability after cell autolysis. Among these minerals, selenium (Se) stands out, which participates in the formation of antioxidant enzymes. The objectives of the work were to define the minimum and maximum concentration of Se that yeasts (Saccharomyces cerevisiae – Y904) support and the concentrations that they tolerate once adapted. To this end, a test of tolerance to Se was carried out, using treatments with different concentrations of Se. The adaptive process started at the maximum concentration obtained in the tolerance test of 60 mg mL-1, with increasing addition of 6 mg mL-1, reaching up to 246 mg mL-1 of Se. The macromorphological characteristics and number of colony forming units (CFU) were evaluated. It was identified that yeasts without adaptation grew on substrate containing up to 60 mg mL-1 of Se and those adapted, up to 246 mg mL-1 of Se. In addition to the reduction in yeast growth speed, from the concentration of 84 mg mL-1 of Se in the medium, morphological changes in colony color were observed. It is concluded that non-adapted yeasts support up to 60 mg mL-1 of Se and, after the adaptive process, they support 246 mg mL-1 of Se in the medium after the adaptive process, which adds value to the final product, and makes yeasts suitable for human nutrition as a supplement or even in the formulation of probiotics.
BORSA, FAİZ, DÖVİZ KURU, ALTIN, PETROL VE BİTCOİN ARASINDAKİ VOLATİLİTE YAYILIMLARI
Authors: ŞENOL Zekai , KOÇ Selahattin
Published: April 2022

Bu çalışmada temel piyasalar arasındaki volatilite yayılımları Diebold ve Yılmaz (2012) tekniğiyle araştırılmıştır. Temel piyasaları temsilen MSCI dünya endeksi, ABD 2 yıllık devlet tahvil faizi, dolar endeksi, ons altın, brent petrol ve bitcoin kullanılmıştır. Çalışmada 2 Ocak 2015 – 29 Haziran 2021 dönemine ait günlük verilerden elde edilen volatiliteler kullanılmıştır. Çalışmada, temel piyasalar arasındaki volatilite yayılım endeksinin %30,9 olduğu, faiz ve MSCI dünya endeksinin volatilite yayıcısı buna karşın dolar endeksi, altın, petrol ve bitcoinin volatilite alıcısı oldukları, faizin temel piyasalarda önemli volatilite yayıcısı olduğu, bitcoinin temel piyasalarla volatilite ilişkisinin zayıf olduğu ve temel piyasalar arasındaki volatilite yayılımlarının COVID-19 sürecinde yükseldiği belirlenmiştir. Elde edilen sonuçlar, portföy yönetimi, risk yönetimi, yatırımlar, ekonomi yönetimleri açısından kullanılabilirlik taşımaktadır.
CHALLENGES IN THE IMPLEMENTATION OF CLINICAL PATHWAY: A QUALITATIVE STUDY AT PRIVATE HOSPITAL IN JAKARTA
Authors: Fushen Fushen , Tj Hery Winoto , Lie Steffe
Published: April 2022

In the universal health coverage era, clinical pathways are generally applied in hospitals for quality and cost control. The utilization of clinical pathways has been widely used and researched. However, limited qualitative research has analyzed the phenomena and challenges for implementing the clinical pathway in Indonesia. This study aims to explore a depth perspective about the challenges in the implementation of the clinical pathway. The results of this study offer alternatives that can complement existing studies and encourage improvement in the use of clinical pathways in Indonesia. This study uses a single case study qualitative approach and descriptive method to describe the challenges of implementing clinical pathways in private hospitals. The challenges encountered were awareness problems, workload imbalances, different perceptions of doctors, and suboptimal hospital management.
Analisa Kualitas Pelayanan Publik: Studi Terhadap Pelayanan Surat Ijin Mengemudi Di Polres Bantul Tahun 2021
Authors: Ardiyanti Anita , Triputro R. Widodo
Published: April 2022

Peningkatan kualitas pelayanan kepada masyarakat selalu ditingkatkan, tidak terkecuali pada pelayanan SIM oleh Kepolisian Republik Indonesia khususnya di Satpas Polres Bantul, Polda DIY. Pelayanan SIM selalu ditingkatkan karena SIM merupakan alat kontrol dan pengendalian penggunaan kendaraan bermotor di jalan raya sebagai identitas diri para pengemudi kendaraan bermotor yang telah dinyatakan mampu mengemudikan, dan sebagai bentuk tanggung jawab bagi Polri maupun pengemudi kendaraan bermotor. Pengendara kendaraan bermotor yang ingin memiliki SIM harus memenuhi prosedur dalam pembuatan SIM. Kesadaran hukum masyarakat yang telah terbentuk harus dapat diimbangi dengan kualitas pelayanan penerbitan SIM yang baik Meskipun peningkatan kualitas pelayanan selalu ditingkatkan, masih terdapat kendala, serta faktor penghambat dan pendukung dalam peningkatan pelayanan. Jenis penelitian ini adalah kualitatif. Hasil penelitian menunjukan, upaya peningkatan kualitas pelayanan pembuatan dan perpanjangan SIM di Polres Bantul adalah sarana dan prasarana yang ada di ruang pelayanan SIM Polres Bantul selalu ditingkatkan demi pelayanan yang lebih baik kepada masyarakat. Di sisi lain, keterbatasan ruang pelayanan SIM Polres Bantul menyebabkan adanya hambatan dalam upaya peningkatan kualitas pelayanan pembuatan dan perpanjangan SIM oleh Satpas SIM Polres Bantul. Selanjutnya data tentang faktor pendukung dalam peningkatan kualitas pelayanan pembuatan dan perpanjangan SIM di Polres Bantul adalah kemampuan petugas Satpas Polres Bantul dalam memberikan pelayanan kepada pemohon SIM di Polres Bantul sudah sangat baik. Petugas di Satpas Polres Bantul sopan dan ramah dalam memberikan pelayanan kepada pemohon SIM. Empati dan simpati yang ditunjukkan oleh petugas di Satpas Polres Bantul dapat dirasakan oleh masyarakat yang sedang mengurus perpanjangan maupun penerbitan SIM baru.
Evaluation of Antioxidant and Antimicrobial Potential of Green Synthesized Ag Nanoparticles from Ethanolic Leaf Extract of Thespesia populnea
Authors: Charulatha S. , Dharrunya H. V. , Dhanamurugan R. , Devadharshini R. , Paul Debanjoy , Sinduja M. E. , Bindhu J.
Published: April 2022

Thespesia populnea is a variety of small tree found mostly in the tropical regions of the world belonging to the family of Malvaceae. According to ancient and traditional medicine such as Ayurveda this plant is used to treat various diseases such as bloody diarrhea, fracture healing, urinary tract problem, abdomen swelling, pleurisy, skin disorders, high fever and menstrual issues. This study focuses on the evaluation of antioxidant and antimicrobial activities of synthesized silver nanoparticles from aqueous leaf extract of Thespesia populnea plant. Reducing capability of synthesized nanoparticles was examined by carrying out various antioxidant assays such as reduction of DPPH substrate through radical scavenging. It showed the maximum reduction of DPPH as 92.77% at 120 ?g/mL concentration. At 120 ?g/mL concentration, phosphomolybdenum showed highest contraction percentage ranging 51.47 % and followed by Fe3+ reduction at 28.78 %. Studies on antimicrobial activity has revealed that the maximum zone of inhibition was exhibited by Proteus vulgaris with distinct zone formation up to 19 mm diameter.
Electro-Homeopathy based COVID-19 Safe-home Medical Management Study
Authors: Taki G. S. , Kumar Mallick Asok , Chakraborty Bishu , Pal Prithwiraj , Biswas Chaitanya , Samanta Chiranjit
Published: April 2022

In the middle of April 2021, the infection rate due to 2nd wave of COVID-19 attained a peak alarming level. Total COVID-19 hospital accommodation became inadequate with respect to the demand of COVID-19 patients. Several unused schools, community halls and auditoriums were converted to safe-homes for COVID-19 patients and home isolated accommodations. Two local clubs at Salt Lake, Sector 4, Kolkata was collaborated to run a COVID-19 Safe-home at Basanti Devi Vidyapith, Basanti Devi colony, at the beginning of May 2021. On behalf of the coordinators, a few Electro-Homeopathy (EH) practitioners were voluntarily engaged themselves to look after the patients. A complete report on the successful management of COVID-19 patients using Electro-Homeopathy treatment has been presented here in details. The efficacy of Electro-Homeopathy for COVID-19 treatment and in-depth details of the philosophy of EH along with EH treatment methodology has been discussed.
In Silico Screening of Triphala Churna against Bacterial Agents
Authors: Dhivya L. S. , Haritha M. , Anjana G. V. , Priya D.
Published: April 2022

Triphala Churna consisting Triphala and its constituents have been revealed to have antibacterial properties against human pathogens. The phenolic ring of phytochemicals has been confirmed to be toxic against microorganisms and hence responsible for antibacterial effect. It has also been found to possess antimicrobial, anti-inflammatory, anti-oxidant, and other properties. The objective of this project is to investigate which bioactive compounds of Triphala churna have antibacterial action and can protect humans from infection. The majority of the molecules in phytochemical examination were positive for ethanolic and acetone extracts and the physicochemical characteristics were within the acceptable limits. In silico data clearly explains that the compounds of Triphala churna follows Lipinski’s rule of five. The toxicity profile and ADME parameters of the compounds revealed that most of the compounds were nontoxic towards carcinogenicity, mutagenicity, and reproductive effect. Based on the energy type of interaction between these molecules and the study protein, molecular docking revealed that the three compounds from Triphala churna own the highest docking score against InhA protein: Terflavin B (-9.67 Kcal/mol), Ellagic acid (-9.37 Kcal/mol), and Corilagin (-8.57 Kcal/mol).
Concerning the Article - A Perspective Review on Siddha System of Medicine in the Management of Corona Virus Disease 2019
Authors: Karunanithi Samraj , Shanmugam Rajalakshmi
Published: April 2022

No Abstract.
Evaluation and Assessment of the Acute Toxic Potential of Sansevieria cylindrica and Plumeria obtusa Plant Extracts in Wistar Albino Rats
Authors: Shewale Sunil , Undale Vaishali , Bhalchim Vrushali , Desai Shivani , Shelar Maruti , Padole Shubham , Chitlange Sohan , Wawale Vikas , Parekh Sameer , Pujari Pramod
Published: April 2022

Sansevieria cylindrica (SC) Bojer ex Hook. (Asparagaceae) and Plumeria obtusa (PO) L. (Apocynaceae) are indoor and outdoor ornamental plants respectively. These plants are traditionally used by the local healers during accidental injuries. However, their toxicological properties are very poorly explored over folkloric usage. Therefore, the present study evaluated the toxic potencies of SC leaves and PO seed Hydro-Alcoholic Extract (SCPOHAE) through acute oral dose (14-days) administration in female Wistar rats. Safety of the SCPOHAE was evaluated as per Organization for Economic Co-operation and Development (OECD) Acute Oral Toxicity study guidelines 423. The female Wistar rats were divided into three groups (n=3). A single oral dose of 2000 mg/kg of body weight of individual extract and 1:1 blend was administered to each animal. The animals were closely observed for clinical signs, neurobehavioral changes, morbidity, and mortality if any for the first half an hour and then every hour for the first four hours followed by observation every 24–hours for 14 days. Changes in food and water consumption, body weight were monitored daily during the study. On day 1 and day 15 blood samples were collected to evaluate changes in the hematology and biochemistry parameters. The urine samples were also collected for urine analysis parameters. Animals were sacrificed on day 15 and organ samples of liver and kidney were collected for histopathological findings. The SCPOHAE individually and also as 1:1 blend at the limit dose (2000 mg/kg, body weight) did not cause death and did not induce any remarkable and abnormal clinical signs, indicative of systemic toxicity, in rats during the treatment period of 14–days. The statistically non-significant small differences in the body weight were observed. Conclusion: The oral administration of SCPOHAE did not cause any systemic toxic effects. In conclusion, the No-observed-Adverse-Effect Level (NOAEL) of these extracts in rats was found to be greater than 2000 mg/kg.
Political alignment and the allocation of the COVID-19 response funds - evidence from municipalities in Poland
Authors: Matuszak Piotr , Totleben Bartosz , Piątek Dawid
Published: April 2022

This paper aims to analyse the allocation of the COVID-19 response funds from the perspective of the political alignment hypothesis. The authors focus on the allocation of the second and third rounds of the Governmental Fund for Local Investments (part of the COVID-19 Response Fund) in Poland. Using the logit and OLS models and the regression discontinuity design the authors show that mayors aligned with the central government were significantly more likely to receive the funds, as well as in higher per capita values, than mayors aligned with the opposition or unaligned with any party in parliament when the allocation was based on a discretionary decision. The results support the political alignment hypothesis and highlight the danger of partiality in the allocation of the COVID-19 response funds.
Histomorphological Study of Thymus in Japanese Quail (Coturnix coturnix japonica)
Authors: Kadam S.D. , Waghaye J.Y. , Thakur P.N.
Published: April 2022

Background: Thymus is the primary lymphoid organ in avian. It is a site of differentiation and maturation of T lymphocytes. Quail thymus showed age related involution with decrease in its volume and cellular contents. It is a lymphoepithelial organ and thus plays a major role in the anti-infection defense mechanism. Methods: For the present study 48 Japanese quail birds reared and thymus was collected from 12 birds each at end of first week, second week, third week and fourth week. The tissue was processed for routine paraffin embedding and processed for different staining procedures for histomorphological studies. Result: In all age group of birds, each thymic lobe was enclosed by thin connective tissue capsule. Thymic lobule was found to be composed of outer cortex and inner medulla. Cortex was composed of lymphocytes, lymphoblasts, myoid cells, macrophages, plasma cells and epithelial reticular cells and that of medulla was composed of lymphocytes, lymphoblast, epithelial reticular cells, myoid cells, macrophages, plasma cells, cyst and Hassall’s corpuscles. The cyst of various shapes and sizes were observed in cortex and medulla. In all age group of birds, unilamilar and multilamilar Hassall’s corpuscles were observed. Number of Hassall’s corpuscles and macrophages were increased with the advancement of age.
Terminal de Autobuses Interprovinciales Sur
Authors:   , Castro Feria Jose Manuel
Published: April 2022

El proyecto es una infraestructura de transporte interprovincial en el sur de la capital, especificamente en el distrito de San Juan de Miraflores, el cual se plantea para complementar la red de terminales terrestres en Lima Metropolitana. La propuesta se enfoca en un proyecto que posea las características de estándares de terminales de autobuses y/o infraestructuras de uso similar contemporáneo, cumpliendo con todos las normas y requerimentos establecidos para su habilitación y adecuado funcionamiento. Asimismo, la propuesta busca proporcionar amplios espacios de facil comprensión visual, áreas y circulaciones claramente diferenciadas y en general enfatizar el uso de la fluidez espacial como elemento principal apoyado por la idea de generar el suficiente confort en sus diversos espacios que vienen a ser el resultado del analisis de los flujos que intervienen en él. Por otro lado, el proyecto al estar ubicado en una zona de gran potencial comercial se ve la necesidad de integrar otras actividades que complementen y se requieran según las características fisicas y funcionales de el usuario y el lugar. Por ello, como parte del programa arquitectonico se ha propuesto que se integre a él un hall comercial que cuente con pequeñas tiendas, cafeterias y/o establecimientos comerciales similiares a ello, un centro de negocios acompañado de pequeñas agencias bancarias y oficinas gubernamentales que en cojunto funcionen y se complementen entre si, y por último un hotel que ofresca todas las comodidades para que el pasajero sienta total placer durante su estadía dentro del edificio.
Escuela de Educación Especial y Centro de Rehabilitación para niños y jóvenes con retraso mental en San Juan de Lurigancho
Authors:   , Caballero Gárate André
Published: April 2022

El tema de tesis presentado es una “Escuela de Educación Especial y Centro de Rehabilitación para Niños & Jóvenes con retraso mental” ubicado en el distrito de San Juan de Lurigancho en la provincia de Lima en el Departamento de Lima. La propuesta arquitectónica resuelve un problema existente en la educación especial de la ciudad de Lima. Debido a la gran población del distrito de San Juan de Lurigancho, se eligió ubicar allí el centro, y de esta manera mejorar la calidad de vida y aumentar la inserción de las personas con habilidades especiales en la sociedad. Mediante la investigación, se logró identificar en el distrito áreas de influencia de los centros de educación especial existentes demostrando las carencias en este servicio para la población. Además, de las deficiencias existentes tanto de la infraestructura como curricularmente. Por esto, el proyecto se unifica bajo una sola administración el CEBE 1 (Retardo Mental) y CEBE 5 (Educación Ocupacional) con un centro de rehabilitación, creando un ambiente propicio y con todas las comodidades para que el alumnado se desarrolle y crezca cada día.
El impacto económico que genera ser anfitrión de los juegos panamericanos
Authors:   , Espinoza Saavedra Bruno , Grigoletto Quevedo Angelo Giuseppe
Published: April 2022

El trabajo de investigación se basa en modelos económicos utilizados por distintos autores para medir el impacto económico que le generaría realizar juegos olímpicos al país anfitrión. Este modelo de mínimos cuadrados ordinarios es replicado en el escenario de juegos panamericanos. Los estudios existentes sugieren que juegos de esta magnitud pueden generar un aumento del empleo; sin embargo, alcanzan poco consenso sobre la magnitud o duración de ese impacto. El propósito de este estudio es determinar si el hecho de ser sede de un juego panamericano impacta positivamente en el PBI per cápita y la tasa de desempleo del país anfitrión. Para evaluar el impacto económico, las naciones anfitrionas no solo serán analizadas en sí mismas, sino que también se las comparará con las naciones que quedaron en el proceso de licitación.
Correlación entre la Auscultación Dinámica Ligera (DPL) y el Ensayo de Penetración Estándar (SPT) para suelos arenosos de origen aluvial ubicados en el distrito de Chilca, provincia de Cañete – departamento de Lima
Authors:   , Flores Perez Waldo , Chávez Cerdeña Jorge Augusto
Published: April 2022

En aplicaciones geotécnicas, el ensayo de penetración dinámica ligera (DPL) es un método alternativo a la Prueba de Penetración Estándar (SPT) para la determinación de los parámetros del suelo. La exigencia de diversas normativas para correlacionar ambos ensayos in situ y no establecer una metodología para realizarlo, limita el alcance práctico del DPL. La presente investigación desarrolla una metodología y una ecuación de correlación entre el ensayo de penetración dinámica ligera (DPL) y la Prueba de Penetración Estándar (SPT) específicamente para suelos arenosos (SP y SP-SM) ubicados en una zona del distrito de Chilca, provincia de Cañete, departamento de Lima. Para el análisis se utilizaron hasta 393 pares de datos, obteniendo correlaciones lineales entre el número de golpes obtenidos de la prueba de Penetración Estándar-NSPT y del ensayo de penetración dinámica ligera-N10; obteniendo un coeficiente de determinación (R2) entre 84% y 87%. La correlación obtenida se puede aplicar para obtener parámetros del suelo cuando el DPL se utiliza como complemento en investigaciones geotécnicas.
LAS CÁRCAVAS DE BURUJÓN A CONTRACORRIENTE
Authors: Tejela Matías Daniel
Published: April 2022

El rodaje del videoclip “A contracorriente”, de los dos famosos cantantes Álvaro Soler y David Bisbal, se ha localizado en las Cárcavas de Burujón en la provincia de Toledo, para aquéllos que no lo conozcan se trata de uno entre otros muchos de esos lugares donde apetece perderse.
Así se creó Tierra y Tecnología, la revista del Colegio de Geólogos
Authors: Pampliega Higueras Enrique
Published: April 2022

Esta primavera, Tierra y Tecnología, la revista del Colegio de Geólogos cumple 25 años. Es tiempo de mirar atrás y hacer un breve recorrido por aquellos primeros meses de 1991 cuando la Junta de Gobierno del momento decidió acometer el proyecto.
Desierto de la Tatacoa: Marte en Colombia
Authors: Bueno Prieto Jorge Enrique , Martínez Frías Jesús
Published: April 2022

Los análogos planetarios existentes en la Tierra, principalmente los de Marte, son de especial importancia para cubrir distintos objetivos geológicos y astrobiológicos, desde la búsqueda de huellas de vida pasada o presente, a la prueba de prototipos, sensores, espectrómetros,rovers, la validación de modelos científicos y, por supuesto, la preparación de futuras misiones tripuladas al planeta rojo. A esto hay que añadir, su indudable valor educativo y de comunicación social a través del diseño de rutas, más o menos especializadas, dependiendo del nivel didáctico que se pretenda proporcionar.
LA GEODA DE PULPÍ, EL MONUMENTO NATURAL QUE NO TE PUEDES PERDER
Authors: Jordá Bordehore Rafael
Published: April 2022

El pasado 15 de febrero la Geoda de Pulpí y Mina Rica de Pilar de Jaravía (donde se localiza la geoda) fueron declarados Monumento Natural por la Junta de Andalucía. Una figura de protección que se suma a la de Bien de Interés Cultural del que ya disponían las minas de Pilar de Jaravía desde el año 2004.
Investigation of the Control Effect of Single Structural Plane on Stability of Rock Mass Based on Barton-Bandis Criterion
Authors: Kang Jingyu , Pang Xin , Sheng Qian , Fu Xiaodong , Wan Daochun , Xia Luqing , Zhang Shaojun
Published: April 2022

The structural plane plays a decisive role in the development processes of rockburst. In this paper, Barton-Bandis criterion of structural plane and its conversion relationship with Mohr-Coulomb criterion are discussed in detail. Firstly, when the structural plane obeys Barton-Bandis criterion, the value range of the dip angle of the structural plane when it is yield is deduced theoretically, and the yield function of the structural plane is proposed: F=sinA−2β+PsinA. The correctness of the theoretical derivation result is verified by a mapping method and numerical simulation method. Secondly, based on the result of theoretical derivation and assuming that rock obeys Mohr-Coulomb criterion, a fast identification method for the failure modes of rock mass is proposed. The failure modes of rock mass are divided into “no failure”, “failure along structural plane”, “failure along rock”, and “failure along both rock and structural plane”, and the correctness of the fast identification method is verified by numerical simulation. Finally, from the perspective of structural plane failure, a new method for converting Barton-Bandis criterion to Mohr-Coulomb criterion is proposed. Based on the yield of structural plane and relative error of displacement, the differences between the new method and existing conversion methods are compared. The results show that the yield condition determined by the new method is consistent with those determined by Barton-Bandis criterion, and the relative error of displacement is less than the tangent regression method and linear fitting method. In summary, the relevant methods and conclusions of this paper provide theoretical support and technical guidance for the mutual conversion between different criteria and the prediction and identification of rock mass failure modes in rockburst.
CHARACTERIZATION OF GLYCOCUNJUGATE DISTRIBUTION IN THE EPIDIDYMIS OF THE JAVAN MUNTJACS (Muntiacus muntjak muntjak)
Authors: Wahyuni Sri , Sofyan Hamny , Hafizuddin Hafizuddin , Adnyane I Ketut Mudite , Gholib Gholib , Jalaluddin Muhammad , Gani Fadli A. , Adam Mulyadi , Siregar Tongku Nizwan , Agungpriyono Srihadi
Published: April 2022

The presence of glycoconjugates in caput, corpus, and cauda epididymis of the Javan muntjacs was performed using lectin histochemical method. The epididymis organs were obtained from two adult male Javan muntjacs in hard antler stage and then immediately fixed in Bouin’s solution and processed in histological manner. Six types of biotinylated lectins namely Peanut agglutinin (PNA), Soybean agglutinin (SBA), Wheat germ agglutinin (WGA), Ricinus communis agglutinin (RCA), Concanavalin A (Con A), and Ulex europaeus agglutinin I (UEA I) were applied to detect the specific glycoconjugates in the epididymal tissue of muntjacs. The result showed the presence of glycoconjugates were detected by five types of lectins except UEA I in caput, corpus, and cauda epididymis with specific distribution and also the intensity of lectins binding. Glycoconjugates β-galactose, β-glucose, mannose, N-acetyl-galactosamine, N-acetyl-glucosamine, and sialic acid were stained with various intensity in epithelial cells, basal cells, stereocilia, spermatozoa, and stroma of caput, corpus, and cauda epididymis. The presence of sialic acid on the surface of spermatozoa detected by WGA are thought to be play a role on sperm protection during their maturation and transit along epididymal lumen. In conclusion, the difference of glycoconjugates distribution pattern and lectin binding in the epididymal caput, corpus, and cauda of the Javan muntjac indicates the regional differences in epididymal function in spermatozoa maturation.
Remote Monitoring of Well Production Performance Based on Machine Learning
Authors: Wang Biao , Han Guoqing , Lu Xin , Tan Shuai , Zhu Zhiyong , Xiang Huizhu
Published: April 2022

A set of dynamic remote monitoring method of production performance based on Machine Learning is proposed for the production process of electric submersible pump (ESP) well with multi-dimensional parameters. Aiming at dealing with the characteristics of multi-dimensional parameters in the complex production system, to implement dynamic monitoring of production performance. Helping the engineers at data centers to find the anomaly remotely and make response in a timely manner.

It puts forward a procedure for large amount, high dimension and low information density production data in complex production system, using the dimensionality reduction algorithm to reduce the dimensionality into one comprehensive parameter changing over time, time series analysis algorithm for the production anomaly detection and prediction based on Machine Learning. The Principal Component Analysis (PCA) is used to reduce the dimensionality and extract the crucial information. The Autoregressive Integrated Moving Average (ARIMA) model is used to conduct timing anomaly detection, and fbProphet model is used to analyze the dimensionality reduced data to provide prediction of the production.

With the dimensionality reduction, time series comprehensive parameter analysis and anomaly detection method based on Machine Learning, more than 40 ESP wells with 15 dimensions production daily parameters up to 1,000 days were analyzed, which realized the comprehensive description of ESP wells with multiparameter. Although the PCA retained only 47.73% of the information in the first principal component, which may be related with the low information density of industrial big data, the subsequent analysis proved the effectiveness. The time series analysis realized many times anomaly detection during the life period of each ESP well, and visualized the production data and the anomalous events. More than 100 anomalous events were detected in advance and which were robust corresponding to the subsequence real production events, among which 95% agreement rate is achieved. The procedure proposed reported the anomaly events with high confidence up to 90%, and low misstatement rate and omission rate, realized the production perception and abnormal detection in a timely manner. Based on this algorithm, the best time for the well intervention is determined, so that the loss of production is avoided and the revenue is maximized.

The novelty of the procedure of Machine Learning using the multiple production data is in the ability to provide a solution of dealing with the low information density and high noise in the complex multi- dimensional production data of production wells, realize the comprehensive description, analysis and prediction of the production. It is helpful for engineers find the abnormalities in time, and will support the decision making of production, optimization and well intervention for the production.
Downhole Chemical Remediation Via Microencapsulated Media
Authors: Dietz Charles H
Published: April 2022

Objectives/Scope

A new revolutionary method of delivering remedial chemical downhole has been developed. The modality involves utilizing microencapsulated chemical compounds and packaging them in a tubular body which is placed at the base of the bottom hole assembly. Results are compared to conventional downhole chemical treatment methods.

Methods, Procedures, Process

This new approach is based on the established practice of providing pharmacological remediation via a microencapsulated chemical compound that is targeted to a designated location prior to the release of the active chemicals. The method of microencapsulation, packaging and placement of the tool will be discussed. Case studies will also be considered that demonstrate the long-term release rate, the inhibition efficiency of phosphonic acid-based compounds, and the corrosion and paraffin reduction efficacy of the hydrocarbon based encapsulated compounds in the downhole tool. Information will also be presented concerning the modified use of the apparatus on the surface to provide remediation at the wellhead location.

Results, Observations, Conclusions

Historically, managing and inhibiting corrosion, scaling and paraffin deposition downhole required surface chemical applications via a conduit to deliver the remedial chemical compounds. More recent advancements have been made to integrate the inhibitors with ceramic beads which effectively replace a portion of the proppants during the fracturing stage or even during the squeeze application where chemical inhibitor is injected downhole under high pressure to lodge in the formation for short term extended release. A modification of this principle involves dropping solid chemical compounds, in the form of pellets, down the wellbore and ultimately into the long cylindrical cavity below the tubing string called the rathole, where the accumulated mass can rapidly dissolve. There are numerous limitations to this mode of application, not the least of which is rapid dissolution of the chemical compound.

A patented method of microencapsulating the standard array of chemical remedial agents used in the oilfield has been developed. The encapsulation process involves initiating an exothermic, complex organic reaction under controlled conditions. The encapsulated compound is then extruded under pressure to create a solid chemical stick of various proportions. These sticks are then placed inside a metal tube that is perforated and jacketed with screen. This design allows for slow targeted release of the chemical compounds at the placement site of the tool.

New, Additive Information

The novelty of this type of chemical application is in the ability to place one-hundred percent of the active chemical compounds at the exact location downhole where the issues of, scale nucleation, corrosion penetration/impingement and paraffin agglomeration begin. This stands in contrast to surface chemical applications that routinely use diluted chemical remedial agents and apply larger quantities using injection pump scenarios.
Produced Water Treatment and Utilization: Challenges and Future Directions
Authors: Eyitayo Stella I. , Watson Marshall C. , Kolawole Oladoyin
Published: April 2022

Produced water is naturally occurring water that is produced as a byproduct during the exploration and production of oil and natural gas from the subsurface system. Produced water brought to the surface contains high saline content and may also contain Naturally Occurring Radioactive Material (NORM). Therefore, the efficient treatment, use, and disposal of produced water remain a critical issue for the energy industry with environmental and human health implications. Over the years, researchers have presented numerous treatment technologies ranging from physical, chemical, and biological perspectives. Some industries have combined one or two of these methods to improve the treatment quality of produced water required for distinct purposes, and these practices have been extended to the energy industry. As the energy industry strives to sustain production capacities and maintain or increase profitability in this energy-transition era, water production is also rising while there is a reduction in its re-purposing and utilization for energy and environmental industries. Our study focuses on over 100 studies conducted over the past five decades. This study presents a comprehensive overview of the produced treatment methods, challenges regarding the execution and implementation of these methods in the energy industry. We highlight the important fundamental questions that are yet to be addressed and propose new directions for more environmentally friendly and economically viable solutions for the treatment and use of produced water.
Evaluation of the effects of pigments produced by environmental bacteria on cancer cells
Authors: bani Nazanin Hashemi , moazamian Elham , Rezaei Aliakbar
Published: April 2022

Cancers are a collection of incapacitating diseases in which cells initiate to divide and spread to adjacent tissues in an uncontrolled manner. Many researches demonstrated the potential of bacterial pigments as promising anticancer agents Therefore, in this study, the cytotoxic effects of bacterial pigments were evaluated in breast and colon cancer cell lines. In this study, a total of 90 samples were collected from air, water, and soil from 28 different geographical areas of Iran. Forty isolates were selected based on differences in colony color and geographic regions. The MTT assay was used to evaluate the effect of pigment on MCF-7 and SW-48 cells. Bacteria whose pigment had the highest cytotoxic effect on cell lines were selected. Accurate identification was performed using PCR, and their relative purity was measured using TLC. Bacteria isolated from any three ecosystems are capable of producing pigments. Pigment-producing bacteria are more abundant in the soil than air and water. Among pigment-producing bacteria, 3 isolates had the highest cytotoxicity on MCF-7 cells, and 3 isolates had the greatest effect on SW-48 cells. The results of sequencing of isolates at the BLAST site showed that 6 isolates with cytotoxic effects were identified (Micrococcus xinjiangensis, Dietzia, Arthrobacter agilis, Exigubacterium mexicanum, Bacillus beijingensis). Chromatography shows that these pigmented bacteria have different pigment components.Pigment extraction from bacteria can be used as a complementary therapy or other therapies for breast and colon cancer in the future.
Influence of the time discrepancy (TD) between the first grinding wheel cut-out and the second cut-in of two-pass grinding on the hardened layer
Authors: Zhao XiaoFeng , Liu Judong , Xu Kai
Published: April 2022

In this paper, grind-hardening experiment on nodular cast iron QT400 was done with a surface grinder. The effects of the time discrepancy(TD) between the first cut-out of the grinding wheel and the second cut-in of the two-pass grinding on the grinding force, microstructure, micro-hardness and uniformity of the hardened layer depth were studied. Then, by using the measured tangential grinding force, the simulation model of grinding temperature field is established. We concluded that, with the same grinding parameters, increasing TD can reduce micro-hardness and harden layer depth, but the uniformity of the hardened layer increases. However, the change of TD has no noticeable influence on the grinding force and microstructure of the hardened layer. The simulation results show that with the same grinding parameters, reducing the TD can increase the temperature of the workpiece in the second grinding. The experimental results are consistent with the simulation results, and the relative error of the hardened layer depth is 9%. Under the consistent grinding parameters, when TD =6s, the hardened layer depth is moderate and its uniformity is good.
En-Block resection of Renal Cell Carcinoma with tumour thrombus propagating into the intrapericardial Inferior Vena Cava: A transabdominal approach.
Authors: Sidiropoulos Theodoros A , Smyrniotis Vassilios , Parasyris Stavros , Ntella Vassiliki , Margaris Ioannis , Theodoraki Kassiani , Vassiliu Pantelis , Arkadopoulos Nikolaos
Published: April 2022

Background: Renal cell carcinoma (RCC) is the most common primary kidney cancer. In up to 4-10% of patients, the tumor is complicated with malignant thrombus extending to the inferior vena cava (IVC). Complete surgical excision of the RCC and the neoplastic thrombus can be curative. We aim to present a safe alternative transabdominal operative technique applied in six patients diagnosed with RCC and IVC thrombus.Methods: This retrospective analysis was conducted in a tertiary academic center in Athens, Greece. All six patients, that were operated for RCC and level-IV malignant thrombus in our department from January 2009 until March 2020, were screened. Intraoperatively, the infrarenal and intrapericardial IVC were clamped simultaneously with the renal and liver blood inflow. Access to the intrapericardial IVC was obtained via the central tendon of the diaphragm. Results: During the study period 6 patients presented with RCC and level-IV IVC thrombus. All patients underwent radical nephrectomy combined with IVC thrombectomy, without the need for a thoracotomy. Operative and hospital mortality was 0%.Conclusions: The proposed surgical technique may be curative in patients with advanced intracaval thrombus and helps reduce the associated morbidity, mortality, and the overall cost of more extended operations.