bluuebunny/crossref_metadata_2025 huggingface dataset:
The protein tyrosine kinase SYK regulates the alternative p38 activation in liver during acute liver inflammation
Authors: Bang Bo-Ram , Han Kyung Ho , Seo Goo-Young , Croft Michael , Kang Young Jun
Published: November 2019

Two distinct p38 signaling pathways, classical and alternative, have been identified to regulate inflammatory responses in host defense and disease development. The role of alternative p38 activation in liver inflammation is elusive, while classical p38 signaling in hepatocytes plays a role in regulating the induction of cell death in autoimmune-mediated acute liver injury. In this study, we found that a mutation of alternative p38 in mice augmented the severity of acute liver inflammation. Moreover, TNF-induced hepatocyte death was augmented by a mutation of alternative p38, suggesting that alternative p38 signaling in hepatocytes contributed more significantly to the pathology of acute liver injury. Furthermore, SYK-Vav-1 signaling regulates alternative p38 activation and the downregulation of cell death in hepatocytes. Therefore, it is suggested that alternative p38 signaling in the liver plays a critical role in the induction and subsequent pathological changes of acute liver injury. Collectively, our results imply that p38 signaling in hepatocytes plays a crucial role to prevent excessive liver injury by regulating the induction of cell death and inflammation.
Origin of Fresnel problem of two dimensional materials
Authors: Wang Xiaodong , Chen Bo
Published: November 2019

Reflectance, transmittance, and absorption of materials are also known as materials’ Fresnel problem. It is widely accepted that Interface model can be utilized to solve Fresnel problem of two dimensional materials. Here, we question the validity of Interface model. Theoretical and experimental results of two dimensional materials are analyzed, and theoretical optical response of two dimensional materials is derived based on thin film model. A new simple, approximate formula of 4πnkd/λ is proposed for calculation of absorption of two dimensional materials. It is found that, in essence, Interface model is a kind of approximate style of thin film model, the main difference between two models is term of (n2 − k2) at normal incidence. A significant error is introduced into reflectance calculation of two dimensional materials when Interface model is utilized. Thus, it is not correct to use Interface model to solve Fresnel problem of two dimensional materials. Thin film model rather than Interface model can be used to universally solve Fresnel problem of two dimensional materials, and exhibit a better agreement with experimental reflectance results than Interface model. Unexpectedly, on contrary to other remarkable, intriguing properties, two dimensional materials exhibit an ordinary Fresnel optical response, which is same with thin film.
Super Damping of Mechanical Vibrations
Authors: Au-Yeung Ka Yan , Yang Brian , Sun Liang , Bai Kehang , Yang Z.
Published: November 2019

We report the phenomenon of coherent super decay (CSD), where a linear sum of the displacement of several damped oscillators can collectively decay much faster than the individual ones in the first stage, followed by stagnating ones after more than 97% of the energy has been dissipated. The parameters of the damped oscillators for CSD are determined by the process of response function decomposition, which is to use several slow decay response functions to approximate the response function of a fast decay resonator. Evidence established in experiments and in finite element numerical simulations not only strongly supported the numerical investigations, but also uncovered an unexplored region of the tuned mass damper (TMD) parameter space where TMD’s with total mass less than 0.2% of a stainless steel plate can damp its first resonance at 100 Hz up to a damping ratio of 4.6%. Our findings also shed light onto the intriguing underline relationships between complex functions with different singular points.
Copy Number Variations in a Cohort of 420 Individuals with Neurodevelopmental Disorders From the South of Brazil
Authors: Chaves Tiago Fernando , Baretto Nathacha , Oliveira Luan Freitas de , Ocampos Maristela , Barbato Ingrid Tremel , Anselmi Mayara , De Luca Gisele Rozone , Barbato Filho Jorge Humberto , Pinto Louise Lapagesse de Camargo , Bernardi Pricila , Maris Angelica Francesca
Published: November 2019

Chromosomal microarray (CMA) is now recommended as first tier for the evaluation in individuals with unexplained neurodevelopmental disorders (ND). However, in developing countries such as Brazil, classical cytogenetic tests are still the most used in clinical practice, as reflected by the scarcity of publications of microarray investigation in larger cohorts. This is a retrospective study which analyses the reading files of CMA and available clinical data from 420 patients from the south of Brazil, mostly children, with neurodevelopmental disorders requested by medical geneticists and neurologists for diagnostic purpose. Previous karyotyping was reported for 138 and includes 17 with abnormal results. The platforms used for CMA were CYTOSCAN 750K (75%) and CYTOSCAN HD (25%). The sex ratio of the patients was 1.625 males :1 female and the mean age was 9.5 years. A total of 96 pathogenic copy number variations (CNVs), 58 deletions and 38 duplications, were found in 18% of the patients and in all chromosomes, except chromosome 11. For 12% of the patients only variants of uncertain clinical significance were found. No clinically relevant CNV was found in 70%. The main referrals for chromosomal microarrays (CMA) were developmental delay (DD), intellectual disability (ID), facial dysmorphism and autism spectrum disorder (ASD). DD/ID were present in 80%, facial dysmorphism in 52% and ASD in 32%. Some phenotypes in this population could be predictive of a higher probability to carry a pathogenic CNV, as follows: dysmorphic facial features (p-value = < 0.0001, OR = 0.32), obesity (p-value = 0.006, OR = 0.20), short stature (p-value = 0.032, OR = 0.44), genitourinary anomalies (p-value = 0.032, OR = 0.63) and ASD (p-value = 0.039, OR = 1.94). The diagnostic rate for CMA in this study was 18%. We present the largest report of CMA data in a cohort with ND in Brazil. We characterize the rare CNVs found together with the main phenotypes presented by each patient, list phenotypes which could predict a higher diagnostic probability by CMA in patients with a neurodevelopmental disorder and show how CMA and classical karyotyping results are complementary.
Surgical fat removal exacerbates metabolic disorders but not atherogenesis in LDLR−/− mice fed on high-fat diet
Authors: Liu Lin , Liang Chenxi , Wang Xiaowei , Ding Xiayu , Lu Yingjing , Dong Jinghui , Han Mei , Yang Hongyuan , Gao Mingming , Liao Jiawei
Published: November 2019

Lipodystrophy is a severe adipose dysfunction that can be classified as congenital or acquired lipodystrophy, in term of the etiology. Previous knowledge about the metabolic disorders and cardiovascular consequences were mostly obtained from lipodystrophic mice with genetic defects. To completely rule out the genetic influence, we established a mouse model of acquired generalized lipodystrophy by surgical removal of multiple fat depots, including subcutaneous fat in the inguinal, visceral fat in the epididymis and brown fat in the scapula, in atherosclerosis-prone LDLR−/− mice which were fed with a high-fat diet (HFD). It was observed that fat removal increased diet-induced hyperlipidemia, especially hypercholesteremia, as early as 2 weeks after HFD and till the end of HFD feeding. After 12 weeks on the HFD, the residual fats of fat-removed mice were found expanded. Although fat removal aggravated diet-induced lipid deposition in the liver and systemic insulin resistance, there was no significant difference in atherogenesis in fat-removed mice compared with sham-operated control mice. Acquired generalized lipodystrophy by surgical fat removal promoted metabolic disorders but not atherogenesis in LDLR−/− mice fed on HFD.
Exposure to linguistic labels during childhood modulates the neural architecture of race categorical perception
Authors: Timeo Susanna , Mento Giovanni , Fronza Erica , Farroni Teresa
Published: November 2019

Perceptually categorizing a face to its racial belonging may have important consequences on interacting with people. However, race categorical perception (CP) has been scarcely investigated nor its developmental pathway. In this study, we tested the neurolinguistics rewiring hypothesis, stating that language acquisition modulates the brain processing of social perceptual categories. Accordingly, we investigated the electrophysiological correlates of race CP in a group of adults and children between 3 and 5 years of age. For both groups we found a greater modulation of the N400 connected with the processing of between category boundaries (i.e., faces belonging to different race groups) than within-category boundaries (i.e., different faces belonging to the same race group). This effect was the same in both adults and children, as shown by the comparable between-group amplitude of the differential wave (DW) elicited by the between-category faces. Remarkably, this effect was positively correlated with racial-labels acquisition, but not with age, in children. Finally, brain source analysis revealed the activation of a more modularized cortical network in adults than in children, with unique activation of the left superior temporal gyrus (STG) and the inferior frontal gyrus (IFG), which are areas connected to language processing. These are the first results accounting for an effect of language in rewiring brain connectedness when processing racial categories.
Author Correction: Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes
Authors: Diamanti Klev , Cavalli Marco , Pan Gang , Pereira Maria J. , Kumar Chanchal , Skrtic Stanko , Grabherr Manfred , Risérus Ulf , Eriksson Jan W. , Komorowski Jan , Wadelius Claes
Published: November 2019

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Perioperative Transthoracic Lung Ultrasound for Assessment of Pulmonary Outcome in Adolescent Idiopathic Scoliosis Patients: Prospective, Observational Pilot Study
Authors: Chang Hae Wone , Won Young Ju , Lim Byung Gun , Suh Seung Woo , Lee Dong Kyu , Lee Il Ok , Ji Sul Gi , Kim HeeZoo
Published: November 2019

The purpose of study was to evaluate the perioperative lung ultrasound findings of patients undergoing scoliosis correction. LUS examination was performed examined three 3 times for each patient: 20 min after starting mechanical ventilation of the lungs(preoperative), after surgery when the patient was placed in the supine position(postoperative), and 20 min after arrival in the post-anaesthesia care unit. Arterial blood gas analyses, mechanical ventilation parameters, peripheral oxygen saturation(SpO2) were also checked. Twenty-six patients completed the study. The changes of LUS score(20 min) was significantly negatively correlated with the partial pressure of arterial oxygen(PaO2)/fraction of inspired oxygen(FiO2) ratio change(P = 0.039, r = −0.40). The change in mean convex side LUS score was significantly greater than that of the concave side as determined by two-factor repeated measures analysis of variance(p = 0.001). Multiple regression analysis revealed perioperative LUS change was the significant factor related to the oxygen index change (p = 0.042). One case of pneumothorax was diagnosed and pleural thickening more than 5 mm was detected in 8 patients and five patients of those were diagnosed pleural effusion and performed thoracentesis after surgery. Postoperative increase of LUS score was related with deteriorating of oxygenation at one day after surgery, and it suggests that lung ultrasound allows prediction of postoperative hypoxia and facilitates the diagnosis of pulmonary complications at operation room in AIS patients.
Non-contact acquisition of brain function using a time-extracted compact camera
Authors: Ando Takamasa , Nakamura Tatsuya , Fujii Toshiya , Shiono Teruhiro , Nakamura Tasuku , Suzuki Masato , Anzue-Satoi Naomi , Narumi Kenji , Watanabe Hisashi , Korenaga Tsuguhiro , Okada Eiji , Inoue Yasunori
Published: November 2019

A revolution in functional brain imaging techniques is in progress in the field of neurosciences. Optical imaging techniques, such as high-density diffuse optical tomography (HD-DOT), in which source-detector pairs of probes are placed on subjects’ heads, provide better portability than conventional functional magnetic resonance imaging (fMRI) equipment. However, these techniques remain costly and can only acquire images at up to a few measurements per square centimetre, even when multiple detector probes are employed. In this study, we demonstrate functional brain imaging using a compact and affordable setup that employs nanosecond-order pulsed ordinary laser diodes and a time-extracted image sensor with superimposition capture of scattered components. Our technique can simply and easily attain a high density of measurement points without requiring probes to be attached, and can directly capture two-dimensional functional brain images. We have demonstrated brain activity imaging using a phantom that mimics the optical properties of an adult human head, and with a human subject, have measured cognitive brain activation while the subject is solving simple arithmetical tasks.
Sodium fluorocitrate having inhibitory effect on fatty acid uptake ameliorates high fat diet-induced non-alcoholic fatty liver disease in C57BL/6J mice
Authors: Hong Seung A. , Jung Ik-Rak , Choi Sung-E. , Hwang Yoonjung , Lee Soo-Jin , Son Youngho , Heo Yu Jung , Cui Rihua , Han Seung Jin , Kim Hae Jin , Lee Kwan Woo , Kang Yup
Published: November 2019

Non-alcoholic fatty liver disease (NAFLD) is excessive fat build-up in the liver without alcohol consumption and includes hepatic inflammation and damage. Excessive influx of fatty acids to liver from circulation is thought to be a pathogenic cause for the development of NAFLD. Thus, inhibition of fatty acid intake into hepatocyte would be a maneuver for protection from high fat diet (HFD)-induced NAFLD. This study was initiated to determine whether sodium fluorocitrate (SFC) as a fatty acid uptake inhibitor could prevent palmitate-induced lipotoxicity in hepatocytes and protect the mice from HFD-induced NAFLD. SFC significantly inhibited the cellular uptake of palmitate in HepG2 hepatocytes, and thus prevented palmitate-induced fat accumulation and death in these cells. Single treatment with SFC reduced fasting-induced hepatic steatosis in C57BL/6J mice. Concurrent treatment with SFC for 15 weeks in HFD-fed C57BL/6J mice prevented HFD-induced fat accumulation and stress/inflammatory signal activation in the liver. SFC restored HFD-induced increased levels of serum alanine aminotransferase and aspartate aminotransferases as hepatic injury markers in these mice. SFC treatment also improved HFD-induced hepatic insulin resistance, and thus ameliorated HFD-induced hyperglycemia. In conclusion, inhibition of fatty acid mobilization into liver through SFC treatment can be a strategy to protect from HFD-induced NAFLD.
Deletion of PLCγ1 in GABAergic neurons increases seizure susceptibility in aged mice
Authors: Kim Hye Yun , Yang Yong Ryoul , Hwang Hongik , Lee Ha-Eun , Jang Hyun-Jun , Kim Jeongyeon , Yang Esther , Kim Hyun , Rhim Hyewhon , Suh Pann-Ghill , Kim Jae-Ick
Published: November 2019

Synaptic inhibition plays a fundamental role in the information processing of neural circuits. It sculpts excitatory signals and prevents hyperexcitability of neurons. Owing to these essential functions, dysregulated synaptic inhibition causes a plethora of neurological disorders, including epilepsy, autism, and schizophrenia. Among these disorders, epilepsy is associated with abnormal hyperexcitability of neurons caused by the deficits of GABAergic neuron or decreased GABAergic inhibition at synapses. Although many antiepileptic drugs are intended to improve GABA-mediated inhibition, the molecular mechanisms of synaptic inhibition regulated by GABAergic neurons are not fully understood. Increasing evidence indicates that phospholipase Cγ1 (PLCγ1) is involved in the generation of seizure, while the causal relationship between PLCγ1 and seizure has not been firmly established yet. Here, we show that genetic deletion of PLCγ1 in GABAergic neurons leads to handling-induced seizure in aged mice. In addition, aged Plcg1F/F; Dlx5/6-Cre mice exhibit other behavioral alterations, including hypoactivity, reduced anxiety, and fear memory deficit. Notably, inhibitory synaptic transmission as well as the number of inhibitory synapses are decreased in the subregions of hippocampus. These findings suggest that PLCγ1 may be a key determinant of maintaining both inhibitory synapses and synaptic transmission, potentially contributing to the regulation of E/I balance in the hippocampus.
Inverse Correlation Between Left Atrial Appendage Function and CHA2DS2-VASc Score in Patients with Atrial Flutter
Authors: Wu Mei-Yao , Lin Yen-Nien , Wu Hung-Pin , Huang Ying-Ying , Chen Jan-Yow , Lin Kuo-Hung , Chang Kuan-Cheng
Published: November 2019

Impaired left atrial appendage ejection fraction (LAA-EF) and peak LAA flow velocity (LAA-FV) are associated with high thromboembolic risks in patients with atrial fibrillation (AF). Herein, we examined LAA function among patients with atrial flutter (AFL) stratified by the CHA2DS2-VASc score using transesophageal echocardiography (TEE). Of 231 consecutive patients with typical AFL, 84 who fulfilled the inclusion criteria were enrolled. Among them, 57 had ongoing AFL and were divided into the isolated AFL (n = 38) and AFL with paroxysmal AF (PAF) (n = 19) groups, depending on whether they had sporadic AF before TEE. The remaining 27 patients with spontaneous sinus rhythm during TEE were designated as controls. Both the LAA-FV (31.9 cm/s vs. 51.5 cm/s, P = 0.004) and LAA-EF (28.4% vs. 36.5%, P = 0.024) measured during AFL were significantly lower in the AFL + PAF group than in the isolated AFL group. Significant inverse correlations between the CHA2DS2-VASc score and LAA-EF were identified in the AFL (P = 0.008) and AFL + PAF (P = 0.032) groups. We observed progressive LAA dysfunction in patients with AFL + PAF compared with that in patients with isolated AFL, and the LAA-EF was inversely correlated with the CHA2DS2-VASc score in these patients. Our findings may have implications on the application of thromboprophylactic therapy in patients with AFL.
Real-time monitoring of newly acidified organelles during autophagy enabled by reaction-based BODIPY dyes
Authors: Liu Hanzhuang , Song Wenting , Gröninger Delia , Zhang Lei , Lu Yinghong , Chan Kin Shing , Zhou Zhikuan , Rurack Knut , Shen Zhen
Published: November 2019

Real-time monitoring of newly acidified organelles during autophagy in living cells is highly desirable for a better understanding of intracellular degradative processes. Herein, we describe a reaction-based boron dipyrromethene (BODIPY) dye containing strongly electron-withdrawing diethyl 2-cyanoacrylate groups at the α-positions. The probe exhibits intense red fluorescence in acidic organelles or the acidified cytosol while exhibiting negligible fluorescence in other regions of the cell. The underlying mechanism is a nucleophilic reaction at the central meso-carbon of the indacene core, resulting in the loss of π-conjugation entailed by dramatic spectroscopic changes of more than 200 nm between its colorless, non-fluorescent leuco-BODIPY form and its red and brightly emitting form. The reversible transformation between red fluorescent BODIPY and leuco-BODIPY along with negligible cytotoxicity qualifies such dyes for rapid and direct intracellular lysosome imaging and cytosolic acidosis detection simultaneously without any washing step, enabling the real-time monitoring of newly acidified organelles during autophagy.
Controlled strong excitation of silicon as a step towards processing materials at sub-nanometer precision
Authors: Dinh Thanh-Hung , Medvedev Nikita , Ishino Masahiko , Kitamura Toshiyuki , Hasegawa Noboru , Otobe Tomohito , Higashiguchi Takeshi , Sakaue Kazuyuki , Washio Masakazu , Hatano Tadashi , Kon Akira , Kubota Yuya , Inubushi Yuichi , Owada Shigeki , Shibuya Tatsunori , Ziaja Beata , Nishikino Masaharu
Published: November 2019

Interaction of a solid material with focused, intense pulses of high-energy photons or other particles (such as electrons and ions) creates a strong electronic excitation state within an ultra-short time and on ultra-small spatial scales. This offers the possibility to control the response of a material on a spatial scale less than a nanometer—crucial for the next generation of nano-devices. Here we create craters on the surface of a silicon substrate by focusing single femtosecond extreme ultraviolet pulse from the SACLA free-electron laser. We investigate the resulting surface modification in the vicinity of damage thresholds, establishing a connection to microscopic theoretical approaches, and, with their help, illustrating physical mechanisms for damage creation. The cooling during ablation by means of rapid electron and energy transport can suppress undesired hydrodynamical motions, allowing the silicon material to be directly processed with a precision reaching the observable limitation of an atomic force microscope.
The effect of additives and intermediates on vanadia-based catalyst for multi-pollutant control
Authors: Huang Xu , Liu Zhan , Wang Dong , Peng Yue , Li Junhua
Published: November 2019

The influence of additives, WO3 and MoO3, on the activity of V2O5/TiO2 catalyst for NOx and chlorobenzene (CB) removal (multi-pollutant control, MPC) was investigated.
Mn2O3/Al2O3 cathode material derived from a metal–organic framework with enhanced cycling performance for aqueous zinc-ion batteries
Authors: Gou Lei , Mou Ke-Liang , Fan Xiao-Yong , Zhao Ming-Juan , Wang Yue , Xue Dong , Li Dong-Lin
Published: November 2019

Rechargeable aqueous zinc-ion batteries (ZIBs) are considered to be potential candidates for large-scale energy storage due to their high capacity, low cost, high safety and environmental friendliness.
Two-fold interpenetrated Mn-based metal–organic frameworks (MOFs) as battery-type electrode materials for charge storage
Authors: Wang Kuaibing , Lv Bo , Wang Zikai , Wu Hua , Xu Jiangyan , Zhang Qichun
Published: November 2019

Two novel interpenetrated 2-fold Mn-MOFs were successfully prepared and applied for the first time in a charge-storage field. As a result, the bulk electrodes behave as alkaline batteries and deliver high capacities of 1004 and 619 C g−1 at 1 A g−1.
The structures and luminescence properties of Sr4Gd3Na3(PO4)6F2:Ce3+,Tb3+ green phosphors with zero-thermal quenching of Tb3+ for WLEDs
Authors: Jiao Mengmeng , Dong Langping , Xu Qinfeng , Zhang Lichun , Wang Dehua , Yang Chuanlu
Published: November 2019

UV excited, green-emitting Sr4Gd3Na3(PO4)6F2:Ce3+,Tb3+ phosphors with zero-thermal quenching of Tb3+ emission have been obtained and investigated in detail.
Identification and physiological comparison of plant species that show positive or negative co-occurrence with selenium hyperaccumulators
Authors: Reynolds R Jason B , Jones Rachel R , Stonehouse Gavin C , El Mehdawi Ali F , Lima Leonardo W , Fakra Sirine C , Pilon-Smits Elizabeth A H
Published: November 2019

In these studies we identified and compared the properties of plant species that showed positive or negative co-occurrence with selenium (Se) hyperaccumulators in their natural habitat. The main questions addressed were: which species are most abundant directly adjacent to hyperaccumulators, and which are absent? How do Se accumulation and tolerance compare in species found to positively or negatively co-occur with hyperaccumulators? Approaches included field surveys, X-ray microprobe analysis of field samples, and a lab Se tolerance and accumulation study. When 54 hyperaccumulators across two naturally seleniferous sites were surveyed for their five nearest neighboring species, and the relative abundance of these species around hyperaccumulators compared to that in the overall vegetation, some species were identified to positively or negatively co-occur with hyperaccumulators. Several positively co-occurring species showed high Se accumulation capability (up to 900 mg Se per kg dry weight), which may reflect Se tolerance. Leaf X-ray microprobe analysis found relatively more organic forms of Se in two positively co-occurring species than in a negatively co-occurring one. There were elevated soil Se levels around Se hyperaccumulators, and neighbors of Se hyperaccumulators had a higher tissue Se concentration as compared to when the same species grew elsewhere in the area. The elevated soil Se levels around Se hyperaccumulators – likely resulting from litter deposition- may significantly affect the local plant community, facilitating Se-tolerant plant community members but lowering the fitness of Se-sensitive members.
Roles of interfaces in the ideality of organic field-effect transistors
Authors: Wu Xiaofeng , Jia Ruofei , Pan Jing , Zhang Xiujuan , Jie Jiansheng
Published: November 2019

The roles of interfaces in determining the ideality of organic field-effect transistors (OFETs) are comprehensively summarized.
A redox-responsive organogel based on a selenium-containing low molecular mass gelator
Authors: Zhang Haojie , Lu Xiuping , Chen Zhao , Jiang Jianzhong , Chen Yukai
Published: November 2019

A redox-responsive low molecular mass gelator (Chol-Se) with selenium as its redox-active center was designed and synthesized. Responsive transformation of Chol-Se in ethyl acetate between the gelation and solution was achieved.
Triptycene walled glycoluril trimer: synthesis and recognition properties
Authors: Ndendjio Sandra Zebaze , Liu Wenjin , Yvanez Nicolas , Meng Zihui , Zavalij Peter Y. , Isaacs Lyle
Published: November 2019

The synthesis, characterization, and molecular recognition properties of 1 toward organic ammonium ions in water is reported.
Addressable DNA nanotubes with repetitive components
Authors: Bai Tanxi , Wei Bryan
Published: November 2019

We present a new strategy to produce DNA nanotubes based on canonical SSTs with addressability available along the axial direction of the self-assembled tubes, which are also programmably repetitive along the lateral direction.
Theoretical insight on the origin of anelasticity in zinc oxide nanowires
Authors: Tawfik Sherif Abdulkader , Osborne Dale A. , Spencer Michelle J. S.
Published: November 2019

The anelasticity of zinc oxide nanowires is unravelled using density functional theory.
Perylene monoimide and naphthalene-annulated [3,3,3]propellanes: synthesis and device applications
Authors: Lv Lingling , Sun Wenda , Jia Zhenmei , Zhang Guowei , Wang Fuzhi , Tan Zhan'ao , Zhang Lei
Published: November 2019

3D polycyclic aromatic hydrocarbons are synthesized, and their applications for organic field-effect transistors and organic light-emitting diodes are explored.
Synthesis and anion recognition studies of new oligomethylene bis(nitrophenylureylbenzamide) receptors
Authors: García-Elías José , Ochoa-Terán Adrián , Yatsimirsky Anatoli K. , Santacruz Ortega Hisila , Ochoa-Lara Karen , López-Martínez Luis Miguel , Castro-Riquelme Christian L. , García Ángel L. , Madrigal-Peralta Domingo , Labastida-Galván Victoria , Ordoñez Mario
Published: November 2019

Synthesis and supramolecular interaction of new oligomethylene bis(4-nitrophenylureylbenzamide) receptors with different anions.
Cd(ii) removal by Fe(ii) surface chemically modified layered double hydroxide–graphene oxide: performance and mechanism
Authors: Liao Wei , Wang He , Li Hui-qiang , Yang Ping
Published: November 2019

Fe(ii)-decorated LDH–GO composites had a high capacity for Cd(ii) removal. The mechanisms were controlled by surface-induced precipitation and complex formation.
Conformational control of Pd2L4 assemblies with unsymmetrical ligands
Authors: Lewis James E. M. , Tarzia Andrew , White Andrew J. P. , Jelfs Kim E.
Published: November 2019

Steric and geometric constraints were used to design unsymmetrical ditopic ligands that form single Pd2L4 cage isomers with high fidelity.
Harpagide, a natural product, promotes synaptic vesicle release as measured by nanoelectrode amperometry
Authors: Tang Yun , Yang Xiao-Ke , Zhang Xin-Wei , Wu Wen-Tao , Zhang Fu-Li , Jiang Hong , Liu Yan-Ling , Amatore Christian , Huang Wei-Hua
Published: November 2019

Nanoelectrode amperometry was used to monitor DA release inside single DAergic synapses, and demonstrated that harpagide effectively enhances synaptic DA release by reducing intracellular ROS generation and inhibiting α-Syn phosphorylation.
Mechanism of lignocellulose modification and enzyme disadsorption for complete biomass saccharification to maximize bioethanol yield in rapeseed stalks
Authors: Deng Jun , Zhu Xiaobo , Chen Peng , He Boyang , Tang Shang-wen , Zhao Wenyue , Li Xianliang , Zhang Ran , Lv Zhengyi , Kang Heng , Yu Li , Peng Liangcai
Published: November 2019

An integrated strategy for complete lignocellulose saccharification to maximize bioethanol yield under a cost-effective and green-like biomass process in rapeseed stalk.
Nitrogen and phosphorus modification to enhance the catalytic activity of biomass-derived carbon toward the oxygen reduction reaction
Authors: Han Lei , Cui Xingyu , Liu Yanyan , Han Guosheng , Wu Xianli , Xu Chunbao (Charles) , Li Baojun
Published: November 2019

N, P heteroatoms are doped into the carbon derived from Fructus azedarach precursor. The successful application in zinc–air battery illustrates that the N, P synergistic effect makes a bright future for the development of catalytically active carbon.
A combination of glioma in vivo imaging and in vivo drug delivery by metal–organic framework based composite nanoparticles
Authors: Pan Yuan-Bo , Wang Siqi , He Xiuchao , Tang Weiwei , Wang Jianhua , Shao Anwen , Zhang Jianmin
Published: November 2019

Metal–organic framework based composite nanoparticles (Mn-ZIF-8/5-Fu) was used for glioma treatment with high drug loading rate and pH responsive drug delivery capacity. Mn-ZIF-8/5-Fu demonstrated good magnetic resonance imaging capacity.
Bis(benzothiophene-S,S-dioxide) fused small molecules realize solution-processible, high-performance and non-doped blue organic light-emitting diodes
Authors: Hu Liwen , Liu Siyang , Xie Guohua , Yang Wei , Zhang Bin
Published: November 2019

A series of solution-processible blue small molecules based on bis(benzothiophene-S,S-dioxide) fused polycyclic aromatics (FBTO) are synthesized, which show the high EL performance with the maximum current efficiency of 6.37 cd A−1.
Quantifying the composition dependency of the ground-state structure, electronic property and phase-transition dynamics in ternary transition-metal-dichalcogenide monolayers
Authors: Chen Mingwei , Zhu Linggang , Chen Qifan , Miao Naihua , Si Chen , Zhou Jian , Sun Zhimei
Published: November 2019

Structural and electronic transition in the ternary TMD monolayer via doping.
Realising the potential of thermoelectric technology: a Roadmap
Authors: Freer Robert , Powell Anthony V.
Published: November 2019

Thermoelectric generators have the potential to convert heat to electrical power in a range of industrial sectors.
Improved compound image segmentation using automatic pixel block classification with SVM
Authors: Juliet Selwyn Ebenezer , Velayutham Selvi Shunmuga , George Jemi Florinabel Deva
Published: November 2019

Computer screen images such as wallpaper, web pages and powerpoint images are compound images. As these images contain a mixture of textual, graphical, pictorial and smooth regions, compression of computer screen images necessitates accurate classification and segmentation of these regions. In this study, an improved compound image segmentation using automatic block classification with support vector machine (SVM) is presented. First, the input compound image is divided into several non‐overlapping blocks, and then the statistical features embedded in each block are mined after applying discrete wavelet transform. Then, the SVM model is trained effectively by using the informative samples of fuzzy c‐means clustering, which takes block‐level edge features and block neighbourhood information as input. Finally, the compound image is classified into two classes such as text/graphics and picture/background with the trained SVM model. Experimental results show that the proposed method performs automatic block classification with high accuracy. As the proposed classifier uses both structural and contextual information as features, block classification accuracy has been improved to a great extent. Hence, the proposed method has made ∼6.2% improvement in block classification accuracy while comparing with existing approaches.
Frequency reconfigurable slot antenna using metasurface for cognitive radio applications
Authors: Chatterjee Joysmita , Mohan Akhilesh , Dixit Vivek
Published: November 2019

A dual‐port antenna system designed for cognitive radio applications is presented in this study. The structure comprises of an ultra‐wideband (UWB) sensing antenna and a reconfigurable communicating antenna. The former is a stepped slot structure with an offset feed, which covers the whole UWB frequency band from 3 to 10.6 GHz, whereas the latter is a dual‐band slot antenna (DBSA) fed with a fork‐shaped microstrip‐line feed and loaded with two identical layers of meandered metasurfaces (MSs). Frequency agility is realised by rotating the MS layers for the DBSA antenna. The dual‐band communicating antenna has three switchable states with tuning ranges of 28 and 45% in the lower‐ and upper‐frequency bands, respectively. The degree of isolation and gain in all three states are appreciable. The proposed structure is fabricated and measured, which has a good agreement with the simulated results.
Target detection method using multipath information in an underwater waveguide environment
Authors: Yu Ge , Zhao Dexin , Piao Shengchun
Published: November 2019

Interface scattering in the ocean environment consistently results in reverberation and multipath echo, thereby decreasing the detection probability of moving targets. In this work, a new detection method which fully uses underwater acoustic channel characteristics to realise high detection probability for moving targets is proposed. First, this method combines fractional Fourier transform and fractional convolution theory to build a delay time–Doppler shift matrix related to multipath echoes. Second, the insensitivity of linear modulated frequency signal and distribution of multipath echo analysis are utilised to detect the moving target in a severe environment. Simulation results show that the proposed method can obtain higher detection probability and more accurate parameter estimation than the traditional method. Experimental results also verify that the proposed method has favourable performance even in strong reverberation environment.
Application of hydraulic press for testing powered roof prop supports
Authors: Kipczak Piotr , Władzielczyk Krzysztof
Published: November 2019

The report presents the possibility of using press forging, used in a smelter in the crushing and forming steel ingots processes, to the operation of compression powered roof supports. Press have been redeveloped which is to construct, to produce and to exchange handles so that they can be mounted in these housing racks in an upright position. Given the capability of measured quantities, measurement procedure and methodology of the study. There were presented some exemplary results of the tests.
Enhancement of Open-Pit Mining Efficiency by Means of Quality Improvement of Open-Pit Excavators Design and Operating In Specified Conditions
Authors: Zykov Pyotr , Zvarych Evgeny , Karasev Andrei , Weber Dieter
Published: November 2019

The objective set in the research is the following: to develop the methodology and application tools for assessment of the open-pit excavators engineering level when selecting and designing them for specific mining-geological and technical service conditions. To achieve the objective, the methods of statistical data analysis, methods of regression models and of mathematical experimentation building, analysis and synthesis, methods of comprehensive assessment of the engineering level indicators, as well as mathematical modeling and appliance of linear algorithm were used. As a result, there was developed the methodology of comprehensive assessment of engineering level and parameters optimization of open-pit shovel excavators, there was also developed a software package, based on the methodology mentioned above, that allows science-based selection of excavators that possess optimum parameters for the specified conditions.
Computer model of electric drive of 1L100K conveying unit
Authors: Zolkin Denis , Petrov Vadim
Published: November 2019

The paper deals with the problems of vibration damping and limiting dynamic loads in the electromechanical system of a belt conveyor by means of an adjustable electric drive. A conveying unit is represented as a three-mass ring system, which corresponds to a conveying unit with cinematically closed tape. The development of the structure of the control system for electric drives of belt conveyors with limited dynamic loads in elastic elements will reduce the dynamic loads on the belt and therefore the wear of the belts. Conditions of damping of oscillations in electromechanical system of belt conveyors are defined.
Application potential analysis of heat accumulator for mining mechanisms
Authors: Rybár Radim , Beer Martin
Published: November 2019

The paper deals with the application potential analysis of heat accumulators for mining machines working in cold climatic conditions. The proposed concept works with the idea of accumulating waste heat generated by the operation of an internal combustion engine, with use of exhaust heat, heat from the radiator and heat from the drive of the hydraulic system. An important innovative element is the use of the heterogeneous structure of phase change material - sodium acetate as a storage substance and a metal foam matrix. The use of sodium acetate enable to store heat for a long period of time without heat loss and the metal foam matrix significantly increases the thermal conductivity. The presented paper deals with the analysis of the functionality of the heat accumulator prototype and with the description of the key phase of the working cycle - heat accumulation.
Allocation of the geo-dynamically hazardous zones during intensive mining of flat-lying coal seams in the mines of SUEK-Kuzbass JSC
Authors: Yutiaev Evgeny , Meshkov Anatoly , Popov Anton , Shabarov Arcady
Published: November 2019

Hazardous and ineffective mines were closed, and a number of underground and strip mines of a modern technological level were built as a result of the restructuring of the coal industry in Russia. However, safety in the coal mines continues to be one of the urgent issues nowadays. In underground coal mining, the main types of risks are processes occurring in the rock mass as a result of mining operations. It is necessary to realize timeous and the most accurate prediction of harmful events, which occur during a development of coal fields, to increase the efficiency and reduce the cost of coal mining. The most optimal and, at the same time, comprehensive approach to predicting possible natural hazardous events in the process of modern coal mining are considered in this article. The results of implementation of integration of different methods of geodynamic and geomechanics researches are presented in this paper.
Research of characteristics of PJSC “Koks” coal and coke dust fuel briquettes
Authors: Solodov Vyacheslav , Cherkasova Tatyana , Kolmakov Nikolay , Subbotin Sergey , Radchenko Yuriy
Published: November 2019

Known methods for the production of fuel briquettes are studied and an analysis of their qualitative characteristics is carried out in the present work. Based on the analysis of existing methods, pilot briquetting of a mixture of PJSC “Koks” coal and coke dust with various types of binder was carried out. Within the framework of studies, the main requirement for raw materials was the absence of demand for it in the market and in the technological processes of existing industries. It has been established that substandard urea is the best binder of the considered ones, since briquettes with its use have high strength and low sulfur content. Comparative briquetting by single and impulse pressing methods was carried out. It is shown that greater briquette strength is achieved by impulse pressing method. It has been established that the process of utilizing finely dispersed carbon-containing wastes is aimed not only at obtaining a new marketable type of fuel and at saving natural resources, but also at improving the environmental situation through the rational use of secondary material resources.
Resource Regions as an Initial Base for Transformation of the Russian Commodity-Based Rental Economy Model
Authors: Kusurgasheva Ludmila , Lubyagina Lydia , Stefanek Pawel , Lapinskas Arunas
Published: November 2019

The article analyzes the current commodity-based rental model of economical growth in Russia. In the conditions when the Russian economy faced serious challenges and risks both within the country and on the outer contour, the question of inertial development possibility and the need to modernize the existing model has become particularly relevant. The aim of the work is to demonstrate the inefficiency, the exhaustion of the commodity-based rental model in relation to growth of opportunities and the futility in relation to the capitalist world-system laws of the development. The article shows that at the present stage the transition from the commodity-based rental model of economical growth to a nationally oriented model of development is possible through the implementation of a new industrialization policy, whereby the resource regions should shift to a sustainable inclusive growth.
Ecological Consciousness in a Shift of Scientific Paradigms
Authors: Yazevich Mariya , Kalinina Oksana , Zhironkina Olga
Published: November 2019

The analysis of the relationship between environmental conscious and scientific paradigms in different Western civilization development periods is presented in the article. The peculiarities of the influence of classical, non-classical and post-non-classical science on the types of environmental conscious characteristic of modern and postmodern societies are studied. The provision on the existence of the connection between the logical and philosophical attitudes of the New European (classical) science and the formation of the principles of anthropocentric environmental conscious that have ensured the formation of the anthropogenic civilization is proved. It is determined that within the framework of the non-classical paradigm the theoretical and philosophical foundations of the eco-centric model of environmental conscious begin to take shape. In the post-non-classical era the model of eco-centrism and worldview orientations directed to the development of the strategy for the safe interaction of nature and man is being formed on the basis of the theories of postmodernism and under the influence of modern cognitive practices. The influence of ontological and epistemological attitudes dominating within the framework of scientific paradigms on the formation of principles of nature management in anthropocentric and eco-centric systems of ecological conscious is traced.
Expert Evaluation of the Risks in Coal-Mining Enterprises Based on Fuzzy Logic
Authors: Raevskaya Elena , Pimonov Alexander , Mihailov Vladimir
Published: November 2019

The article is about a complex approach based on the method of analyzing hierarchies and using of fuzzy logics for assessment of risks deals with innovations in coal mining industry. This approach allows evaluating both quantitative and qualitative risk indicators of compared alternative innovative projects, does not depend on a field of expertise, thus it makes possible to attract specialists with competencies in various fields of knowledge. Such kind of approach allows making a qualitative assessment of the situation on the basis of formalized logical conclusions, making decision making comfortable and accessible to any specialist. The proposed methodology is implemented as part of a decision support system.
The Unity of the Trajectory of Sustainable Development of the Mining Region and Ensuring its Environmental Safety
Authors: Sheveleva Oksana , Slesarenko Ekaterina , Kudrevatykh Natalia , Mamzina Tatiana
Published: November 2019

Environmental safety can be considered as an integral and one of the most important parts of the concept of sustainable development of a coal-mining region, since the environmental risks occupy one of the leading places among the risks of backbone enterprises of such regions due to the particularities of the coal industry and its impact on the environment. In the article, environmental safety is assessed through indicators of the quality of atmospheric air and water, as well as investments in the restoration and protection of the environment; discrepancies were revealed between the amount of financial investments allocated to nature restoration measures and the results of the anthropogenic impact of coal mining enterprises on the biosphere; emphasis was placed on the need to improve the efficiency of funds allocated for environmental protection and rational use of natural resources. Considered priority areas of environmental activities implemented in the framework of the environmental policy of JSC SUEK-Kuzbass. The effectiveness of the system of environmental remediation measures developed by the Company, their adequate funding, makes it possible to place the Company among the industry leaders in environmental and social responsibility for its activities.
Digital ecosystem of the region and the competitiveness of Kuzbass coal enterprises
Authors: Samorodova Lyudmila , Shut’ko Larisa , Yakunina Yulia , Lyubimov Oleg , Kovacs Péter
Published: November 2019

The issues related to the formation of the digital ecosystem in the coal-mining region within the framework of the world project “industry 4.0” are investigated. It is proved that the prospects for the development of the coal-mining region are associated with its export orientation and diversification of the economy, its complication. Technological momentum based on the use of digitization and cyber-physical systems will lead to a significant reduction in the cost of time for the implementation of manufacturing operations, which enhances the market potential of manufactured production, its competitiveness by reducing production costs, the energy costs of its manufacture and, accordingly, offered prices. The most active processes are the formation of the digital ecosystem and the use of the “Internet of Things” in the mining industry, which indicates a new stage of restructuring in this industry. Russia has accumulated “positive” experience related to the implementation of projects “smart mine” and “intellectual open-cast mine” in Kuzbass mines and coal cuts. The increasing complexity of the regional ecosystem through digitalization and automation of production will contribute to the growth of competitive advantages and competitiveness of Kuzbass coal-mining enterprises.