bluuebunny/crossref_metadata_2025 huggingface dataset:
Pembuatan Website Untuk Meningkatan Pelayan Bidang Informasi Dan Komunikasi Publik Di Diskominfotik Provinsi Bengkulu
Authors: Soba Aldo Lata , Syahputra Deo , Adriansyah Muhammad
Published: March 2024

Diskominfotik Provinsi Bengkulu telah melakukan upaya untuk meningkatkan pelayanan di bidang Informasi dan Komunikasi Publik (IKP). Salah satu solusi yang diambil adalah dengan pembuatan website yang dikelola langsung oleh bidang IKP. Website ini dirancang untuk memberikan akses mudah dan cepat kepada masyarakat dalam mendapatkan informasi terkini seputar kegiatan dan program pemerintah provinsi Bengkulu. Pembuatan website tersebut dilakukan dengan menggunakan teknologi terbaru dan desain yang modern, sehingga memberikan tampilan yang menarik dan user-friendly bagi pengunjung. Selain itu, website tersebut juga dilengkapi dengan fitur-fitur yang memudahkan akses dan interaksi dengan masyarakat, seperti sistem pengaduan online dan ruang diskusi untuk mengajukan pertanyaan atau memberikan masukan. Dengan adanya website yang dikelola langsung oleh bidang IKP, diharapkan dapat meningkatkan pelayanan dan efisiensi dalam memberikan informasi kepada masyarakat. Selain itu, website ini juga diharapkan dapat menjadi sarana promosi bagi potensi-potensi yang dimiliki oleh Provinsi Bengkulu, sehingga dapat menarik minat investasi dan wisatawan untuk berkunjung ke daerah tersebut.
The Science Student Electronic Exit Ticket (SEET) System
Authors: Raza Ali , Sumner Tamara , Penuel William R.
Published: March 2024

This study examined the ways in which an equity analytics tool — the SEET system — supported middle school science teachers’ reflections on the experiences of diverse students in their classrooms. The tool provides teachers with “equity visualizations” — disaggregated classroom data by gender and race/ethnicity — designed to support teachers to notice and reflect on inequitable patterns in student participation in classroom knowledge-building activities, as well as “whole class visualizations” that enable teachers to look at participation patterns. The visualizations were based on survey data collected from students reflecting on the day’s lessons, responding to questions aligned with three theoretical constructs indicative of equitable participation in science classrooms: coherence, relevance, and contribution. The study involved 42 teachers, divided into two cohorts, participating in a two-month professional learning series. Diary studies and semi-structured interviews were used to probe teachers’ perceptions of the visualizations’ usability, usefulness, and utility for supporting their reflections on student experiences and instructional practices. A key result is that only the “equity visualizations” prompted teacher reflections on diverse student experiences. However, despite the support equity visualizations provided for this core task, the teachers consistently ranked the whole class visualizations as more usable and useful.
As árvores e a música brasileira
Authors:   Universidade Federal de São Carlos – UFSCar Araras Brasil, Viani Ricardo Augusto Gorne
Published: March 2024

As árvores influenciam e permeiam a vida de todos nós, assim como a música. O Brasil é o campeão mundial em diversidade de árvores, que têm sido uma inspiração a muitos músicos, desde tempos longínquos até os dias atuais. Este livro traz canções da música brasileira que abordam ou citam árvores e as árvores que estas citam. O livro tem três seções. Primeiro são trazidas canções generalistas que falam de árvores sem citar espécies, depois são apresentadas canções que falam concomitantemente de múltiplas espécies de árvores e por último são trazidas canções específicas sobre 125 árvores, as quais são descritas e representadas por fotografias de mais de 220 espécies. QRCodes disponíveis em cada seção do livro conduzem os leitores a playlists, permitindo a audição das centenas de canções citadas. Espera-se que o livro contribua para que pessoas conectadas à música conheçam melhor árvores nativas e exóticas presentes no Brasil, passando a valorizar a abastada natureza que temos. Aos já conhecedores das árvores, o livro apresenta parte do nosso diversificado cancioneiro popular, abrindo as portas para o apreço por novos sons e artistas.
Anti-Gender Backlash: Where is Philanthropy?
Authors: VeneKlasen Lisa
Published: March 2024

This working paper explores how philanthropic institutions with a history of supporting women’s and LGBTQI+ rights and democracy are seeing and responding to anti-gender backlash, and the background dynamics shaping the struggle. It is based on a scan commissioned by the Countering Backlash, Reclaiming Gender Justice research programme. The paper seeks to contribute to an analysis of the dynamics of patriarchal backlash by looking at the perspectives and priorities of the private philanthropic institutions on which many of the groups and initiatives affected by and challenging anti-gender backlash depend for their survival.
Üretim Farklılıkları Ve Bölgesel Etkenlerin Orta Çağ Avrupa’sında Tuz Ticaretine Etkisi
Authors: YAVAŞ Halil
Published: March 2024

Bu çalışmada, Orta Çağ Avrupası’nda tuz üretim yöntemleri ve tuz ticareti ele alınacaktır. Bu amaçla öncelikle tuzun dönem toplumları açısından önemi üzerinde durulacaktır. Saklama koşullarının çok zor olduğu çağlarda gıdadan, cenazelerin muhafazasına kadar geniş bir kullanım alanına sahip olan tuz, bir değişim aracı ve ticari emtia olarak da karşımıza çıkmaktadır. Bu hususlar değerlendirildikten sonra konunun daha iyi izah edilebilmesi için dönemin Avrupası’ndaki tuz üretim teknikleri ele alınacak ve mukayese edilecektir. Bu süreçte özellikle kaya tuzu ile denizden elde edilen tuz arasındaki farklılıklar irdelenecek, devamında tuz üretim bölgeleri tek tek incelenecek, üretim tekniklerinin bölgesel koşullar ile bağlantısı örnekler verilerek araştırılacaktır. Bütün bu başlıklar, kuzeyden güneye bir sıralamaya tabi tutularak, her bölgenin fonksiyonları ve önemi üzerinde değerlendirmelerde bulunulacaktır. Bu noktada özellikle Orta Çağ’ın ikinci yarısından itibaren Avrupa’da yükselen tuz ticareti üzerinde durulacak, Alman ticaret örgütü Hansa Birliği ve İtalyan devletlerinin tesiri ele alınacaktır. Bunun yanında manastırların tuz üretimindeki etkileri ve vergilendirme hususunda bazı değerlendirmeler olacaktır. Akabinde elde edilen bulgulardan yola çıkılarak sonuç bölümünde çıkarımlar sunulacaktır.
Barriers and Strategies in the Implementation of Virtual Learning Modalities Amid COVID-19 among Students in Nursing Schools at Sulu Province, Philippines
Authors: Mukattil Nursidar , Pangandaman Hamdoni
Published: March 2024

Introduction: The COVID-19 pandemic prompted a significant shift toward virtual learning modalities in nursing education. However, this transition has been marked by various challenges, including faculty and student unfamiliarity with online platforms and the need to adapt curricula rapidly. The purpose of this study to examine the barriers and strategies in the implementation of virtual learning among students in nursing schools at sulu province, philippines during the COVID-19 pandemic.
Methods: Quantitative research study with a focus on descriptive analysis was employed to collect and analyze data from 95 nursing students across three higher education institutions in the Sulu Province. A questionnaire was used to assess sociodemographic factors, technology usage, and barriers experienced during virtual learning. Data were analyzed using frequency, percentage, mean, and standard deviation.
Results: The results revealed that most participants were between 19 and 20 years old, with a higher percentage of females. The majority of students reported owning and using various online technologies, including online videos, social media platforms, mobile apps, and email. Key barriers to virtual learning included the absence of face-to-face interaction, poor internet connectivity, limited technical support, restricted access to clinical simulations, and distracting home environments. Language barriers, technical jargon in learning materials, limited access to required software, insufficient opportunities for collaboration, and privacy and security concerns were also identified as barriers.
Conclusion: The findings underscore the importance of implementing key strategies to enhance virtual learning modalities in nursing education. These strategies can significantly improve the quality and effectiveness of virtual learning in nursing education, especially in challenging contexts like the Sulu Province.
Quantifying of surface urban heat island intensity in Isfahan metropolis using MODIS\Terra\LST data
Authors: Montazeri Majid , Abolfazl Masoodian Seyed
Published: March 2024

Heat island characteristics depend on the background climate of the site where the city is located. Therefore, an index was defined for the Isfahan metropolitan area to quantify the surface urban heat island intensity. This new index is based on the representative pixels of urban and non-urban areas. For this purpose, MODIS land cover type product (MCD12Q1) data were used to distinguish between urban and non-urban areas. Also, data from the MODIS/Terra land surface temperature product (MOD11A1) from 2000 to 2018 were utilized for daytime and nighttime to study the surface heat island intensity. Then, the representative pixels of urban and non-urban areas were identified using the spatial correlation method, and the heat island index was calculated for the metropolitan area of Isfahan. The study showed that the frequency distribution of the nighttime heat island index follows a normal distribution and is often 3.5 to 4º K above the temperature of the surrounding areas of the city. The 365-day floating mean of the surface urban heat island reveals that this index has increased in recent years. The research of temporal behavior showed that the intensity of the surface urban heat island reaches its maximum in January and becomes weaker in summer, while the survey of spatial behavior showed that the core of the surface urban heat island extends towards downtown areas, where the oldest part of the city is located.
PENERAPAN KONSEP TQM DALAM MENINGKATKAN MUTU PENDIDIKAN SD ISLAM DAARUL MUWAHIDIN SEMARANG
Authors: Ibadillah Banna Irfan
Published: March 2024

Munculnya Total Quality Management (TQM) dewasa ini dirasa sebagai jawaban atas problem lembaga pendidikan dalam meningkatkan mutu pendidikan. Makalah ini bertujuan untuk mendeskripsikan beberapa konsep-konsep TQM yang diterapkan oleh SD Islam Daarul Muwahidin yaitu (1) orientasi pada kepuasan konsumen, (2) komunikasi dan kerjasama antar karyawan, (3) dan upaya dalam meningkatkan SDM karyawan. Metode yang digunakan adalah pendekatan kualitatif dalam ranah studi kasus dan penulis menganalisis data dengan 4 langkah: mengumpulkan data, mengklasifikasi, memaparkan, lalu menyimpulkan. Sedangkan hasil dari makalah ini menunjukkan bahwa SD Islam Daarul Muwahidin menerapkan konsep TQM dalam meningkatkan mutu pendidikan yang ditawarkan. Terutama dalam mengintegrasikan antara ilmu-ilmu umum dengan nilai-nilai keislaman. Dari 3 konsep TQM yang dibahas sebagai rumusan masalah, ditemukan adanya keterikatan antara konsep-konsep TQM lainnya yang diterapkan oleh SD Islam Daarul Muwahidin Semarang.
A formalist analysis in how Lewis Carroll portrays Alice character in "Alice's Adventures in Wonderland"
Authors: Asgar Widhasworo Rochmansyah Putra  , Alifian Kusuma Bahtiar  , Wahyu Indah Mala Rohmana
Published: March 2024

The researcher of this study article presents a formalist analysis of Alice's characterization in the novel "Alice's Adventures in Wonderland" from the point of view of the author of the fictional work Lewis Caroll. This research article explores how Alice's actions, dialogues, and interactions contribute to her characterization, emphasizing the traits of curiosity, open-mindedness, empathy, and assertiveness. It also investigates the role of each episode in shaping Alice's journey and highlights the importance of dreams, growth, and her encounter with the Caterpillar. The article concludes by emphasizing the formalist perspective and references various dissertations, conference proceedings, and books related to the analysis of Alice's character in the novel.
The Impact of Productive Zakat on the Development of Mustahiq Businesses in Kecamatan Tualang
Authors: Marsa Salsabila , Arsyianti Laily Dwi
Published: March 2024

The Covid-19 pandemic had a significant impact on the development of microbusiness. The restrictions of social activities decrease sales which have affected the capitalist economy. Productive zakat funds can be a solution in dealing with these problems. This research aims to determine the characteristics of mustahiq and their business and analyze the factors affecting mustahiq total revenue after distributing productive zakat during the Covid-19 pandemic and its impact. The contribution of research related to the effect of productive zakat can be helpful for several parties, such as the government, zakat management organizations, especially BAZNAS Siak Regency, and academics. The method used is descriptive analysis, multiple linear regression analysis, and paired t-test. The results showed a difference in the total revenue of business before and after productive zakat distribution during the Covid19 pandemic. The factors that positively and significantly affect business total revenue after the issuance of productive zakat during the Covid-19 are capital, the number of zakat funds, dummy education, and dummy business type. The business duration affects negatively and significantly; however, the respondents' age doesn't affect total revenue increments significantly.
Antecedents of e-WOM and Revisit Intention in Sharia Hotels: Application of Social Exchange Theory
Authors: Dinisa Dinda , Gayatri Gita
Published: March 2024

Revisit intention is one of the most important factors in determining a hotel’s long-term success, as well as the spread of positive feedback by guests through electronic word-of-mouth (e-WOM). Sharia-compliant hotels, in comparison to conventional ones, face limitations in number and require substantial development. Hence, the primary objective of this study is to examine the factors that influence the creation of eWOM and the intention of guests to revisit, considering the direct, indirect, and moderating influence of guests’ religiosity levels. This study was conducted by distributing questionnaires to 312 respondents, employing the Structural Equation Model- Partial Least Square (PLS-SEM) method for data analysis. The results of this study provide insight into the significant influence of guests’ religious levels in Sharia-compliant hotels on their intention to revisit, directly or indirectly. These findings have significant implications for understanding the essential determinants for attracting returning guests and fostering the more effective growth of Sharia-compliant hotels in Indonesia, contributing to both theoretical insights and practical applications.
Surgical Treatment of Late Developmental Dysplasia of the Hip in Bladder Exstrophy
Authors: Alhussainan Thamer S. , Alahmari Mousa Saeed , Essa Ahmed Faris , Alshwieer Mohammed A. , Aloqail Tariq Sulaiman A.
Published: March 2024

Case:

We present a case of an 8-year-old boy with classical bladder exstrophy and a neglected right hip dislocation, exemplifying the risk of missed developmental dysplasia of the hip (DDH) in patients with exstrophy requiring careful orthopaedic oversight.

Conclusions:

When treating patients with bladder exstrophy, physicians and surgeons should be vigilant not to miss associated DDH. If this condition requires surgical treatment, preoperative planning with computed tomography scans is vital to uncovering the complexities arising from abnormal pelvic and acetabular anatomy and ensuring successful treatment outcomes.
Diagnosis and Management of Lower Extremity Chronic Exertional Compartment Syndrome in the Active Adult Population
Authors: Jensen C. Taylor , Stonerook Ethan , Andreski Allie , Goldsmith Kimberly , Vallejo Cynthia Solis , Tran Lan Michelle , Wade Erin , Gillette Chris
Published: March 2024

Chronic exertional compartment syndrome can significantly alter the quality of life and level of physical activity participation in active adults. This lesser known and understood condition requires diligent physical examinaion and linear diagnostic progression to appropriately diagnose. Although surgical intervention is the definitive treatment modality, there are multiple surgical approaches which could be considered and several nonoperative conservative therapies which can be trialed to meet patients' physical performance goals.
Intrabulbar, Intraorbital and Intracranial Perforating Eye Injury with Foreign Body: A Case Report
Authors: Shoshi Mire , Shoshi Flaka , Shoshi Fitore
Published: March 2024

Ocular trauma is a significant cause of preventable blindness and visual impairment worldwide. Eye globe perforation can happen due to work with sharp tools or different particles that are spread during work with metals, wood, and other solid substances.We present the case of a 14-year-old male patient admitted as an urgent case at the Ophthalmology Department in 2014 due to a perforating eye injury with a foreign body – a 7 cm rusty metallic nail in the right eye. The X-ray of the orbit revealed that the foreign body had penetrated the eyelid, the eye eyeball, and through the orbit and its posterior wall, penetrated the skull and 2 cm in the brain. Under general anesthesia, we performed the anterior chamber lavage, excision of the prolapsed iris, and pupilloplasty. The anterior chamber was reconstructed using a saline solution (0.9% NaCl) and air. The patient was treated conservatively with antibiotics and steroids for 10 days; there were no signs of wound filtration, hypotonia, or endophthalmitis. Due to the limited resources for the posterior segment surgery, the patient was referred to another center for pars plana vitrectomy (PPV) after 10 days of hospitalization in the Department of Ophthalmology at the University Clinical Center of Kosovo. After PPV with silicon oil and cataract surgery, the patient could see the light and its projections (BCVA = L+P+). We followed up on the patient until September 2022, there were no signs of bulbus atrophy, and the visual acuity remained the same, BCVA = L+P+. The correct diagnosis and treatment at the right time play a leading role in achieving one of the main goals of surgical treatment of perforating eye injuries, which is the preservation of the anatomical structure and the physiology of the eye.
Mutation Detection in MYO15A Gene in an Iranian Family with Non-Syndromic Hearing Loss
Authors: Mostafa Neissi Mostafa Neissi , Mohammadi-Asl Misagh , Roghani Mojdeh , Al-Badran Adnan , Mohammadi-Asl Javad
Published: March 2024

Hearing loss, recognized as one of the most prevalent sensory disorders, encompasses both syndromic and non-syndromic manifestations, with the identification of 87 genes and over 100 genetic loci in autosomal recessive non-syndromic hearing loss marking significant progress in understanding its genetic basis. In this case report, we showcase a non-syndromic hearing loss scenario involving a 21-year-old man experiencing progressive hearing loss. Through whole-exome sequencing, we unveiled a previously unreported homozygous mutation, c.1178_1179delAC; p.Tyr393Serfs*38, located in exon 2 (NM_016239.4) of the MYO15A gene in the proband. The newly identified mutation, causing a new reading frame (p.Tyr393Serfs*38), results in an early encounter with a stop codon, leading to the formation of a shortened protein. These findings advance our understanding of the molecular mechanisms involved in autosomal recessive non-syndromic hearing loss, contributing to broader scientific knowledge and potential breakthroughs in hearing loss research.
Diagnostic Performance of 18F-fluorocholine PET/CT Compared to 99mTc-Sestamibi Scintigraphy in Diagnosis of Parathyroid Adenoma
Authors: Mansour Sahar , Alanazi Anwar , Alshammari Arwa , Almutairi Farah , Dalilah Juna , Hakami Reham , Alhumaidan Safiah , Khaled Shomoukh , Faden Ola , Albatly Abdulrahman
Published: March 2024

Background: In most hyperparathyroidism cases, the disease is related to parathyroid adenoma (PTA). Owing to the inconsistencies of currently approved imaging methods, novel methods for detecting PTA are being evaluated. This study aimed to compare 18F-fluorocholine PET/CT with 99mTc-sestamibi SPECT/CT in identifying PTA in Saudi patients.Methods and Results: The study included 40 adult patients with PTA diagnosed by histopathological findings. 99mTc-sestamibi SPECT/CT and 18F-fluorocholine PET/CT examinations were performed for each patient, and parathyroid hormone (PTH) levels and histologic findings were recorded. The diagnostic ability of 18F-fluorocholine PET/CT (AUC=0.720; P=0.029) was superior to 99mTc-sestamibi SPECT/CT (AUC=0.623; P=0.214) in identifying PTA. The sensitivity and accuracy of 18F-fluorocholine PET/CT (81.5% and 75%, respectively) were significantly (P<0.05) higher than that of 99mTc-sestamibi SPECT/CT (63% and 62.5%, respectively). 18F-fluorocholine PET/CT findings were correlated significantly (P=0.023) with PTH results. Conclusion: 18F-fluorocholine PET/CT is a diagnostic imaging method superior to conventional modality 99mTc-sestamibi SPECT/CT in the detection of PTA and, thus, allows for accurate preoperative localization.
Assessment of Sperm Morphometry in Evaluating Male Infertility
Authors: Hussein Ramadan , Mohamed Essam-Eldeen , Mohamed Refaat , Abdelbasset Walid , Morsy Wessam , Elsayed Shereen
Published: March 2024

Background: Infertility is a complex issue affecting 15% of couples of reproductive age, with men accounting for 40%-50% of infertility cases. Semen analysis comprises various descriptive measures of sperm and seminal fluid to determine semen quality. Transforming qualitative descriptions of sperm deformities and shape changes into quantitative terms can aid in identifying sub-visual abnormalities. This study aimed to evaluate sperm morphometry parameters in both infertile and fertile men. Methods and Results: The study enrolled a total of 101 participants, divided into three groups: Group A included 38 subfertile patients with varicocele, Group B included 33 patients with idiopathic infertility (23 with asthenozoospermia and 10 with oligozoospermia), and Group C (the control group) included 30 healthy fertile men. The mean age of patients was 31.6±5.81, 31.3±6.0, and 29.47±4.27 years in Groups A, B, and C, respectively. Scrotal duplex examinations were performed to identify the presence of varicocele. Semen samples were collected following WHO Manual (2010). Semen dynamic and morphological analyses were conducted using CASA (Computer-Assisted Semen Analysis, MIRALAB, ISO9001, ISO13485). We found that sperm concentration, total sperm count, sperm progressive motility, and sperm progressive+non-progressive motility were significantly lower in Group A and Group B than in Group C (P=0.000 in all cases); however, there were no differences between Group A and Group B regarding these parameters (Table 5). The sperm morphology index was significantly lower in Group A than in Group C (P=0.0024); no differences were found between Group B and Group C and Group B and Group A. The mean value of the sperm deformity index was significantly lower in Group A than in Group C P=0.004). Conclusion: Our study highlights the significant association between sperm morphology and male infertility in varicocele and idiopathic subfertile males.
Levels of Stress, Anxiety and Depression among Students at Alma Mater Europaea Campus College “Rezonanca,” Kosovo
Authors: Hoxha Valë , Cakolli Vlorë , Bajgora Valmira
Published: March 2024

Background: This study aims to assess the prevalence of psychological well-being, the level of psychological stress and perceived anxiety among dental students at the Alma Mater Europaea Campus College “Rezonanca.” Methods and Results: We evaluated the stress and anxiety levels of 70 students in the fourth year of dentistry studies at the Alma Mater Europaea Campus College “Rezonanca” in Kosovo in the school year 2022/2023. The distribution of students was equal in terms of gender. Participants were surveyed using the DASS-21 questionnaire. A questionnaire with 25 questions was used to determine the most frequent causes of stress. This questionnaire was distributed to the students at the same time as the DASS-21 questionnaire. The questionnaire had 25 questions about stress. Students had the opportunity to choose the level of stress for the respective statement from 1 to 4. The evaluation was done on a Likert scale. Then, the answers were converted into points by multiplying the given answer by 10. There was no statistically significant difference among female and male students on the mean points of depression, anxiety, and stress sub-scales. At the normal range of depression scores were 78.6% of students, followed by 67.1% for normal anxiety levels, and 92.9% for normal stress scores. We found no statistically significant difference in the distribution of the severity rating of depression, anxiety, and stress scores between female and male students. Conclusion: Dental students are exposed to various sources of stress. Stress in DS begins before they are accepted into the dental program and continues until they graduate. To reduce the stress levels among dental students, it is recommended that dental faculties, their clinical mentors, their peers, and colleagues make an effective plan to reduce stress among their students.
Prevalence and Correlation between High-Risk HPV Genotypes and Pap Smear Findings in Bahrain: A Retrospective Approach
Authors: Alnoaimi A , Feda T , Azam Mariam , Syed Saba , Hafiz Khadija , Saad H , Roohi Mahera , Mohammed M
Published: March 2024

Background: Human papillomavirus (HPV) is currently the most common pathogen responsible for cervical cancer (CC), a major cause of cancer-related deaths in women. This study aimed to estimate the current HPV prevalence in Bahrain and to determine the association of high-risk HPV (HR-HPV) genotypes with cytological findings, age, and clinical history of the patients. Methods and Results: Our study used a retrospective approach. Convenience sampling was used to gather 100 cases of HPV-positive women with abnormal and normal Pap smear findings from January 2017 to April 2023 in the Cytology Department at King Hamad University Hospital. Out of 100 HR-HPV positive cases, non-16/18/45 HR-HPV was found in 62%, and 73% had abnormal Pap smear findings. Among Pap smear findings, ASC-US/ASC-H (P=0.038) and LSIL/HSIL(P=0.017) were significantly associated with HR-HPV genotypes.ASC-US was found to be more frequently associated with HPV16+non-16/18/45 HR-HRV and LSIL with HPV18/45+non-16/18/45 HR-HRV. Most HR-HPV cases (59%) were aged ≤40 years, 25% - from 41 to 50 years old, while only 16% were >50. The age group ≤40 had the highest peak with non-16/18/45 HR-HPV genotype (35%) and HPV16 (19%). The predominant genotypes for age groups 41-50 and >50 were non-16/18/45 HR-HPV types (19% and 8%, respectively). Conclusion: In Bahrain, non-16/18/45 HR-HPV infection is becoming more prevalent, with ASC-US being the most common abnormal Pap finding and the highest HPV infection in women aged 40 years or younger.Based on our findings, we recommend effective screening and vaccine programs for women aged 40 years and younger, as early detection can lower infection rates and improve recovery.
Dual RNA-seq analysis unveils the molecular interactions between coconut (Cocos nucifera L.) and Phytophthora palmivora, the bud rot pathogen
Authors: P. Gangaraj K. , K. RAJESH M. , Jangam Ashok Kumar , H. Prathibha V. , V. Ramesh S. , Antony Ginny , Habeeb Jasmin , K. Amritha K. T. , S. Muralikrishna K. , B. Rajitha P. , N. Hemalatha
Published: March 2024

Background
The bud rot pathogen Phytophthora palmivora poses a significant threat to coconut production worldwide. Effective management strategies against this devastating pathogen are lacking due to the absence of resistant cultivars and limited knowledge about its pathogenicity mechanisms. To address this, we conducted dual RNA-seq analyses at three time points (12, 24, and 36 hours post-infection) during the initial progression of the disease, using a standardized in vitro assay. This study aimed to identify transcriptional regulation following infection and decipher the system-level host response to P. palmivora.
Results
Differential gene expression (DGE) analysis between control and infected samples revealed extensive modulation of stress-responsive genes in coconut. In contrast, P. palmivora showed differential expression of genes encoding effector and carbohydrate-active enzymes (CAZy). Pathway enrichment analysis highlighted the up-regulation of genes associated with plant-pathogen interaction pathway and plant hormone signal transduction in coconut. To validate our findings, we selected ten candidate differentially expressed genes (DEGs) from both coconut and P. palmivora for quantification using qRT-PCR at the three time points. The expression trends observed in qRT-PCR confirmed the reliability of the dual RNA-seq data, further supporting the comprehensive outlook on the global response of coconut to P. palmivora infection.
Conclusions
This study highlights the significant modulation of stress-responsive genes in coconut and differential expression of effector and carbohydrate-active enzyme genes in P. palmivora during bud rot infection. The findings provide valuable insights into the molecular interactions and transcriptional regulation underlying the coconut-P. palmivora pathosystem, aiding in the development of effective management strategies against this devastating pathogen.
HVDFusion: An effective fusion framework based on Hilbert vibration decomposition for multi-focal and multi-sensor images
Authors: Choudhary Gaurav , Sethi Dinesh
Published: March 2024

Image fusion (IF) due to its cost-effectiveness and applicability in a broader range of applications makes it an emerging area in research. However, it is seen from the literature that most of the existing fusion algorithms are application-specific. As a result, the results obtained for different applications are limited. So, in this work, we propose an effective algorithm for better outcomes for different applications. For this, an adaptive image decomposition tool known as Hilbert vibration decomposition (HVD) is used. HVD decomposes an image into instantaneous energy components having amplitudes (image amplitudes) and frequencies. Unlike traditional multi-scale decomposition, the adaptive decomposition strategy used by HVD does not require any fixed cut-off frequency or pre-defined function basis and offers better spatial resolution. Then, we compute instantaneous detailed image amplitudes that generally contain significant information. These are obtained by subtracting the instantaneous image amplitudes from the source images. Further, we find the optimized weights with the help of a statistical approach, i.e., by using unbiased estimates and eigenvalues related to these instantaneous detailed image amplitudes. After this computation, the optimized weights are integrated with source images to generate the final fused image. The simulation of the proposed work is carried out in MATLAB software for multi-focus, medical, and visible-infrared (VI-IR) image samples and compared with existing methods. It is seen that in comparison to traditional as well as some deep learning-based fusion works, the proposed work not only provides better/comparative outputs qualitatively and quantitatively but there is also less computational time complexity.
Analysis of flexural behavior of beams and retrofitting using wire mesh and MS plates
Authors: Shahmir Nadeem Gulzar , Wani Tawfeeq Ahmad , Mushtaq Jasir
Published: March 2024

This research reflects the study about the flexural behavior of plain concrete beams and beams retrofitted with Mild steel(MS) plate and wire meshes. The load vs deflection behavior of the plain Concrete beams, MS plate retrofitted beams, and beams retrofitted with steel meshes is compared. Initially, the analytical analysis of the normal beam was studied with the aid of STAAD pro (v8i), and the STAAD RCDC was used for a complete reinforcement design and detailing. Later, the reinforcement provided in the form of steel bars was provided as per the output obtained in STAAD. To study the final flexural behavior, a total number of 9 beams of rectangular cross-sections were cast having uniform cross-sections. The length of the beam was kept at 1200 mm. The width and depth of the beam were kept at 150 and 200 mm respectively. Out of 9 beams, 6 beams were retrofitted, out of which 3 were retrofitted with externally bonded MS(Mild steel) plate and 3 were retrofitted wrapped wire mesh. As per the results obtained, comparing the load vs deflection models of all specimens, this research manifests that retrofitting with mild steel plates and wire mesh leads to a significant increase in the flexural capacity of the beam and due to superior strength-to-weight ratio of wire meshes the beams retrofitted with wire meshes proved more cost-effective.
Transcriptome Profiling Reveals the Molecular Mechanisms Governing Postharvest Senescence in Fresh Bamboo Shoots (Chimonobambusa quadrangularis) upon SNP Treatment
Authors: Xu Jinyang , Ji Ning , Wang Rui , Zhang Ni , Liu Renchan , Li Yuxin , Lei Jiqing
Published: March 2024

Nitric oxide (NO) is a crucial physiological molecule that plays a regulatory role in maintaining the postharvest quality of fruits and vegetables. While previous studies have acknowledged the potential of NO in preserving the postharvest quality of bamboo shoots, the precise mechanism behind this regulatory function remains elusive. In this particular investigation, we aimed to elucidate the underlying mechanism by identifying key genes involved in NO-mediated regulation of postharvest senescence in bamboo shoots (Chimonobambusa quadrangularis). To achieve this, we integrated physiological data with transcriptome data. Notably, our study employed a 0.25 mmol·L− 1 SNP (NO) soaking treatment, which significantly demonstrated its capability to delay senescence, as well as inhibit browning and lignification in bamboo shoots. Transcriptome analysis revealed a total of 5077 genes exhibiting differential expression between the NO treatment group and the control group. Several of these genes were associated with the biosynthesis of lignin, ethylene, and abscisic acid, all of which were notably suppressed. In addition, the expression of genes linked to reactive oxygen metabolism was significantly altered, resulting in a reduction in reactive oxygen species accumulation. Based on our experimental findings, it is evident that NO treatment effectively retards the postharvest lignification and browning of fresh bamboo shoots. This is achieved through the inhibition of lignin biosynthesis, regulation of related plant hormone synthesis, and reduction of reactive oxygen species accumulation, collectively contributing to the delay of postharvest senescence in fresh bamboo shoots. The implications of our study shed light on the potential application of NO treatment in preserving the quality of perishable produce during postharvest handling.
Individual Differences in the Effects of Neighborhood Socioeconomic Deprivation on Economic Decision Making and Psychotic Risk in Children
Authors: Cha Jiook , Park Junghoon , Cho Minje , Lee Eunji , Kim Bo-Gyeom , Kim Gakyung , Joo Yoonjung
Published: March 2024

Understanding how a child's social and economic surroundings influence their mental development and potential for psychological disorders is essential for unpacking the origins of mental health issues. This study, using up-to-date machine learning-based causal inference methods, tested the relationships between neighborhood socioeconomic deprivation, delay discounting, and psychotic-like experiences (PLEs) in 2,135 children considering the wide range of covariates. We found that a greater neighborhood deprivation led to steeper future reward discounting and a higher psychosis risk, evident over 1-year and 2-year follow-ups. We also discovered, across children, significant individual differences in the effect of neighborhood adversity on childhood PLEs, particularly hallucinational symptoms. Children particularly vulnerable to PLEs in adverse neighborhoods exhibited steeper future reward discounting, higher cognitive performance polygenic scores, notable neuroanatomical alterations, including reduced volume, surface area, and white matter in limbic regions. Furthermore, these children displayed increased BOLD reactivity within the prefrontal-limbic system during Monetary Incentive Delay tasks across various reward/loss versus neutral conditions. These findings underscore the intricate interaction between the brain's reward processing mechanisms and external socioeconomic elements in shaping the risk of psychosis in children.
Key Issues in Quantitative Analysis of Physical Energy Consumption
Authors: xing yu , zhou xiaojun , wang zhaohui , zhang jun , wang jian
Published: March 2024

Understanding and mastering the characteristics and laws of physical energy consumption can not only improve work efficiency, but also ensure safety. Currently, physical energy consumption remains at the level of inferring physiological load conditions through changes in exercise load. According to the literature and previous experimental data, it is found that blood pressure and heart rate are highly consistent with the exercise process. Based on the differential and integral results of B.P. and H.R. multiplier curves at different exercise intensities, the rate and amount characteristics of physical energy consumption are analyzed. It is concluded that the key problem of quantitative analysis of physical energy consumption is real-time high-frequency collection of B.P. and H.R., and accurate heat consumption. Consider collecting data on B.P., H.R., heat consumption, and tissue oxygen in various states from different populations, professions, and genders, and construct models for physical energy assessment, exercise risk detection, and physical energy training.
Drug Screening and Contrasting Sensitivities: Adenoid Cystic Carcinoma Cancer Stem Cells and Tumor Cells Differentially React to Histone Modifier Drugs
Authors: Emerick Carolina , Silva Luan César , Jang Yeejin , Squarize Cristiane H. , Castilho Rogerio M.
Published: March 2024

Background
adenoid cystic carcinoma (ACC), a rare malignancy often treated through a multidisciplinary approach, is noted for its slow progression and aggressive behavior. This study focuses on the impact of histone modification drugs (HMD) on ACC tumors and the implications for treatment. Methods: by analyzing the effects of HMD on Cancer Stem Cells (CSC) and non-CSC tumor cells, we investigated the inhibitory effect of various histone-modifying compounds on ACC tumor cells. Our dual-pronged approach used reductions in sphere size and increased cell death as indicators of drug efficacy, employing diverse compounds targeting histones. Results: subsequent validation revealed promising results, with specific drugs showing significant cytotoxicity. Moreover, several as-yet untried in ACC clinical trials showed potential, notably UNC0638, a histone methyltransferase inhibitor, and ITF2357 (Givinostat), an HDAC inhibitor that exhibited significantly high cell-death percentages. Also examined was the specific application of distinct HMD to non-cancer stem cells within ACC tumors. Conclusions: the findings underline the importance of identifying drugs capable of targeting CSC independently from non-CSC tumor cells, as both populations of cells present contrasting sensitivities.
Removal of anionic dyes utilizing Box-Behnken design and cloud point extraction coupled with derivative spectrophotometry
Authors: Sargazi Shahnaz , Ebrahimi Ali Asghar , Ghaneian Mohammad Taghi , Rahmani Mashaallah
Published: March 2024

Cloud point extraction (CPE) was used in this work to eliminate anionic dyes, Cresol red and Methyl orange, in the form of binary combinations. To remove these dyes from aqueous solutions, Triton X-100 was utilized. We chose wavelengths of 365 nm and 520 nm for Cresol red and Methyl orange, respectively, using a derivative spectrophotometer and first-order derivatives. The response surface methodology was then utilized to ascertaint he effect of surfactant concentration, temperature, and time on the dyes' elimination processes. The quadratic mathematical model obtained from the Box-Behnken design (BBD) matrix was used and developed to estimate the influence of each variable and its relationship with the elimination parameters. Using model equations and comparison between predicted and empirical values, coefficients of determination (R2) bigger than 0.97 were obtained. By applying variance analysis, significance and anticipation of models were validated, and process variables were estimated. The data demonstrate that the mentioned dyes adsorption may be described using the model of pseudo-first-order in kinetic modelling. The data illustrates that the analyzed dyes adhere to the Langmuir model, with a correlation value of 0.86 for Cresol red and 0.87 for Methyl orange. The monolayer capacity (Qmax) was determined to be 0.77 mol/mol for Cresol red and 26.41 mol/mol for Methyl orange.
Efficacy and safety of intra-aortic balloon pump in acute myocardial infarction with cardiogenic shock phase B
Authors: Li Mengxian , Hu Liqun , Li Lei
Published: March 2024

Objective
This study was designed to evaluate intra-aortic balloon pump supports interventional therapy in acute myocardial infarction with cardiogenic shock phase B. Methods Two hundred and twenty patients with acute myocardial infarction with cardiogenic shock phase B treated in our hospital from January 2019 to December 2022 were divided into two groups: control group (110 patients receiving interventional therapy) and observation group (110 patients receiving interventional therapy supported by IABP). The length of stay, cardiac function indexes, MACE events and the occurrence of adverse reactions were compared between the two groups. Results There was no statistically significant difference in general data between the two groups (P > 0.05), no statistically significant difference in cardiac function indexes before treatment (P > 0.05), no statistically significant difference in TIMI blood flow level 3 standards and various slow blood flow and non-reflow phenomena between the two groups (P > 0.05). After treatment, left ventricular ejection fraction (LVEF), cardiac output (CO) and cardiac index (CI) in observation group were significantly higher than those in control group, while cardiac function grade, length of stay, N-terminal B-type diuretic pronatriuretic peptide (NT-proBNP), left ventricular work (LVW) and peripheral vascular resistance (PVR) in observation group were significantly lower than those in control group, with statistical significance (P < 0.05). Conclusion IABP supported interventional therapy showed obvious advantages in patients of acute myocardial infarction with cardiogenic shock phase B, with significant improvement in cardiac function, decrease in length of stay, and no increase in the incidence of MACE events and adverse reactions. The early clinical application is worthy of consideration.
Involution Feature Extraction Network Based Human Posture Recognition in Martial Arts Movement Recognition
Authors: Zhang Sifang
Published: March 2024

With the development of computers in recent years, human body recognition technology has been vigorously developed and is widely used in motion analysis, video surveillance and other fields. As the traditional human action recognition relies on video decomposition frame-by-frame, artificially designed motion features to achieve the role of recognition, this approach is both energy-consuming recognition efficiency is also very low. Thanks to the advent of deep learning, computers can automatically extract features from movements and then recognize and classify them. This research is based on deep learning to improve human pose estimation. Firstly, Involution's feature extraction network is proposed for lightweight human pose estimation, which is combined with existing human pose estimation models to recognize human pose. Each joint of the human body is labelled and classified, weights are added to each part, features are extracted between the joints at each moment, and the extracted features are then fed into a long and short term memory neural network for recognition. Experimental results show that the number of parameters and computational effort of the improved human pose estimation model is reduced by around 40% compared to the original model, while still providing a slight improvement in accuracy. The performance of the model under each algorithm is compared with the model proposed in this study, and the results show that the proposed model has better performance in recognizing different martial arts movements.
Binding Energies and Hydrogen Bonds Effects on DNA-cisplatin Interactions: A DFT-xTB Study
Authors: Ludwig Valdemir , Ludwig Zélia M. Costa , Modesto Marlon , Rocha Arthur Augusto
Published: March 2024

xTB and DFT-CAM-B3LYP were used to study hydrogen bonds in DNA basepairs and DNA-cisplatin complexes. Structure, binding energies and electrondensity are analyzed. xTB has proven to be an accurate method of obtainingstructures and binding energies in DNA structures. Our xTB values for DNA basebinding energy the pairs were in the same order and in some cases better thanthe CAM-B3LYP values compared to the experimental values. Double-strandedDNA-cisplatin structures have been calculated and the hydrogen bonds of watermolecules are a decisive factor contribution to the preference for the cisplatin-Guanine interaction. Higher values of the water hydrogen binding energies wereobtained in cisplatin-guanine structures. Furthermore, the electrostatic potentialwas used to investigate and improve the analyzes of the DNA-cisplatin structures.
Effect of Biomin F Toothpaste and Diode Laser on Remineralization of White Spot Lesions (In Vitro Study)
Authors: Eldeeb Amira Ibrahim , Tamish Nazla O. , Madian Ahmed M.
Published: March 2024

Background: White-spot lesions are considered an initial carious stage characterized by an outer enamel layer with significantly reduced mineralization. This study was conducted to assess the combined effect of Biomin F toothpaste and Diode laser on remineralization of white spot lesions.
Materials and methods: An invitro study conducted on a total of 30 premolars divided into three groups; Group A (Biomin F Tooth paste), Group B (Biomin F with laser application for 30 sec), Group C (Negative control).The three groups were submitted to three stages; stage 1:Baseline,stage 2:After demineralization ,and stage 3:After remineralization .In each stage, elemental analysis(calcium, phosphorus, and fluoride)was measured quantitatively using Energy Dispersive X-ray (EDX) analysis and qualitatively by micrographs using scanning electron microscope. The data were tested to find significant difference between mineral changes during stages by using (ANOVA) test and Bonferroni test.
Results: Calcium, phosphorus and fluoride ions decreased in all groups after demineralization. In stage 3, after application of remineralizing agents, Calcium ions increased significantly in groups A and B where P˂.05. As regards to the phosphorus ions, a significant increase was observed in all groups with group A showed the highest gain as phosphorus level percentage change (%mass) was 56.52±18.02 . Fluoride ions increased significantly in groups A and B (p˂0.05) but decreased significantly in group C. There was no statistical significant difference between group A and B (p≥.05) in calcium, phosphorus, and fluoride level after remineralization.
Conclusion: Within the limitation of the present study, we concluded that Biomin F toothpaste is promising in the repairing of white spot lesions on the surface of the demineralized enamel. Diode laser didn’t affect the remineralizing ability of Biomin F toothpaste which add hazard without benefit.