bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploration of key ferroptosis-related genes and immune infiltration in Crohn’s disease using bioinformatics
Authors: Tang Xiaoting , Hu Weitao , You Wei , Fang Taiyong
Published: August 2023

Crohn's disease (CD) is a type of inflammatory bowel disease (IBD) that manifests mainly as chronic inflammation in different parts of the gastrointestinal tract, and its incidence has come to be increasing in recent years. Ferroptosis, a novel type of programmed cell death, it seems the role of ferroptosis-related biomarkers in CD has not been mentioned. Thus, the role of ferroptosis in CD and its relationship with immune infiltration were explored in this study. The CD dataset was downloaded from the Gene Expression Omnibus database. The validated ferroptosis genes (FRGs) were retrieved from the public FerrDb database. The gene expression matrix of the CD dataset was analyzed with the “limma” package in R language to obtain differentially expressed genes (DEGs) between diseased and healthy samples. Then, intersecting genes between DEGs and FRGs were identified as differentially expressed ferroptosis-associated genes (DE-FRGs). Protein–protein interaction (PPI) network analysis and visualization were carried out with STRING and Cytoscape, and key CD ferroptosis-related genes (CD-FRGs) were identified along with their Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways using the clusterProfiler package. Immune cell infiltration was analyzed with CIBERSORT. The correlation between key CD-FRGs and immune-infiltrated cells in CD was studied by Spearman's correlation method. A total of 37 DE-FRGs and 6 key CD-FRGs (CAV1, CD44, HIF1A, IFNG, TIMP1 and TLR4) were identified. GO and KEGG functional analysis indicated these genes enrichment in programmed cell death and apoptotic process, HIF-1 signaling pathway and IBD. Infiltration matrix analysis of immune cells showed abundant T cells CD4 memory activated, M1 macrophages, M2 macrophages, Mast cells activated and Neutrophils in CD intestinal tissues. The 6 key CD-FRGs were correlated with immune-infiltrated cells in CD based on correlation analysis. Taken together, immune cells with abnormal infiltration can be implicated in CD due to ferroptosis. This study identified 6 key CD-FRGs that may be key biomarkers of ferroptosis in CD; they include CAV1, CD44, HIF1A, IFNG, TIMP1 and TLR4. These findings suggest that the immune response is critical in CD caused by ferroptosis through the interaction between key CD-FRGs and immune infiltrating cells.
Cognitive behavioral therapy for lifestyle changes in patients with obesity and type 2 diabetes: a systematic review and meta-analysis
Authors: Kurnik Mesarič Katja , Pajek Jernej , Logar Zakrajšek Bernarda , Bogataj Špela , Kodrič Jana
Published: August 2023

The aim of this systematic review and meta-analysis was to examine the contribution of cognitive behavioral therapy (CBT) to the implementation of lifestyle changes, considering health-related and behavioral outcomes. A systematic literature review was performed using multiple databases (PsycInfo, PubMed and MEDLINE). The inclusion criteria comprised randomised controlled trials of CBT for lifestyle changes in patients with obesity and/or type 2 diabetes. The quality of study reporting was assessed with the revised Cochrane Collaboration’s risk of bias tool. A meta-analysis was conducted on studies with appropriate outcomes. Nine randomised controlled trials, with a total sample size of 902 participants, met the inclusion criteria. The meta-analysis has shown a medium, significant effect size of CBT interventions for weight loss and weight maintenance, and a low, non-significant effect size of CBT interventions for reducing glycated hemoglobin (HbA1c) levels. A separate, combined, meta-analysis for all nine calculated effect sizes has yielded a medium and significant overall effect size for the model. Our review of the studies about the effectiveness of CBT in implementing lifestyle changes has, in comparison to usual control groups, proven the efficacy of CBT interventions in implementing lifestyle changes, especially for weight loss and weight maintenance.
Asparagine restriction enhances CD8+ T cell metabolic fitness and antitumoral functionality through an NRF2-dependent stress response
Authors: Gnanaprakasam J. N. Rashida , Kushwaha Bhavana , Liu Lingling , Chen Xuyong , Kang Siwen , Wang Tingting , Cassel Teresa A. , Adams Christopher M. , Higashi Richard M. , Scott David A. , Xin Gang , Li Zihai , Yang Jun , Lane Andrew N. , Fan Teresa W.-M. , Zhang Ji , Wang Ruoning
Published: August 2023

Robust and effective T cell immune surveillance and cancer immunotherapy require proper allocation of metabolic resources to sustain energetically costly processes, including growth and cytokine production. Here, we show that asparagine (Asn) restriction on CD8+ T cells exerted opposing effects during activation (early phase) and differentiation (late phase) following T cell activation. Asn restriction suppressed activation and cell cycle entry in the early phase while rapidly engaging the nuclear factor erythroid 2-related factor 2 (NRF2)-dependent stress response, conferring robust proliferation and effector function on CD8+ T cells during differentiation. Mechanistically, NRF2 activation in CD8+ T cells conferred by Asn restriction rewired the metabolic program by reducing the overall glucose and glutamine consumption but increasing intracellular nucleotides to promote proliferation. Accordingly, Asn restriction or NRF2 activation potentiated the T cell-mediated antitumoral response in preclinical animal models, suggesting that Asn restriction is a promising and clinically relevant strategy to enhance cancer immunotherapy. Our study revealed Asn as a critical metabolic node in directing the stress signaling to shape T cell metabolic fitness and effector functions.
Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms
Authors: Grockowiak Elodie , Korn Claudia , Rak Justyna , Lysenko Veronika , Hallou Adrien , Panvini Francesca M. , Williams Matthew , Fielding Claire , Fang Zijian , Khatib-Massalha Eman , García-García Andrés , Li Juan , Khorshed Reema A. , González-Antón Sara , Baxter E. Joanna , Kusumbe Anjali , Wilkins Bridget S. , Green Anna , Simons Benjamin D. , Harrison Claire N. , Green Anthony R. , Lo Celso Cristina , Theocharides Alexandre P. A. , Méndez-Ferrer Simón
Published: August 2023

Aging facilitates the expansion of hematopoietic stem cells (HSCs) carrying clonal hematopoiesis-related somatic mutations and the development of myeloid malignancies, such as myeloproliferative neoplasms (MPNs). While cooperating mutations can cause transformation, it is unclear whether distinct bone marrow (BM) HSC-niches can influence the growth and therapy response of HSCs carrying the same oncogenic driver. Here we found different BM niches for HSCs in MPN subtypes. JAK–STAT signaling differentially regulates CDC42-dependent HSC polarity, niche interaction and mutant cell expansion. Asymmetric HSC distribution causes differential BM niche remodeling: sinusoidal dilation in polycythemia vera and endosteal niche expansion in essential thrombocythemia. MPN development accelerates in a prematurely aged BM microenvironment, suggesting that the specialized niche can modulate mutant cell expansion. Finally, dissimilar HSC-niche interactions underpin variable clinical response to JAK inhibitor. Therefore, HSC-niche interactions influence the expansion rate and therapy response of cells carrying the same clonal hematopoiesis oncogenic driver.
How Australian environmental non-governmental organisations frame and enact climate justice
Authors: Gulliver Robyn E. , Vachette Astrid , Boddington Sarah
Published: August 2023

This paper seeks to examine how Australian environmental non-governmental organisations (ENGOs) communicate about and mobilise their supporters for climate justice. ENGOs play an important role in raising awareness and changing values, attitudes and behaviours related to climate justice. However, while many Australian ENGOs have begun incorporating language around climate justice in their communications, it remains unclear how this concept is framed and enacted in practice. Using data collected from 619 ENGO websites and 149 grant applications, we examine how ENGOs describe climate justice and the collective action frames they use to mobilise action. We found that while few ENGOs provided detailed explanations of climate justice on their websites, they primarily framed climate injustice as a procedural and distributive problem. The fossil fuel sector was most commonly identified as the cause of climate injustice, and First Nations communities most commonly affected. ENGOs linked different climate justice dimensions to diverse causes, issues and actions, indicating a nuanced understanding of how climate justice can be enacted in different contexts. However, they primarily proposed incremental tactics involving education, solidarity and allyship behaviours rather than radical actions through which to drive a transformative agenda of social, political or economic change. We conclude the paper with a discussion of applied implications for ENGOs and suggestions for future research.
MFM-300(Sc): a chemically stable Sc(iii)-based MOF material for multiple applications
Authors: López-Cervantes Valeria B. , Obeso Juan L. , Yañez-Aulestia Ana , Islas-Jácome Alejandro , Leyva Carolina , González-Zamora Eduardo , Sánchez-González Elí , Ibarra Ilich A.
Published: August 2023

A summary of the applications of MFM-300(Sc), as well as some emerging advanced applications, have been discussed.
Electrocatalytic hydrogen evolution with a copper porphyrin bearing meso-(o-carborane) substituents
Authors: Peng Xinyang , Han Jinxiu , Li Xialiang , Liu Guijun , Xu Yuhan , Peng Yuxin , Nie Shuai , Li Wenzi , Li Xinrui , Chen Zhuo , Peng Haonan , Cao Rui , Fang Yu
Published: August 2023

A new Cu porphyrin bearing meso-(o-carborane) substituents is designed and synthesized and displays much higher activity than o-carborane-free analogues for the electrocatalytic hydrogen evolution reaction in both organic and aqueous solutions.
Tetrel bonding stabilization of a new coordination polymer constructed from lead(ii) azide and 1-(pyridin-2-yl)ethylidenepicolinohydrazide
Authors: Mahmoudi Ghodrat , Zangrando Ennio , Gurbanov Atash V. , Eftekhari-Sis Bagher , Mitoraj Mariusz P. , Sagan Filip , Safin Damir A.
Published: August 2023

A coordination polymer[Pb3L2(N3)4]nconstructed from Pb(N3)2and 1-(pyridin-2-yl)ethylidenepicolinohydrazide (HL), and computational studies of non-covalent interactions and their physical contributions (Pb⋯N, N⋯N, C–H⋯N and π⋯π) are reported.
Exploring the local work function of metallic materials at the nanoscale: the influence of neighboring phases
Authors: Zhou Wenjie , Dong Chaofang , Chen Dihao , Wang Li , Cheng Xuequn , Li Xiaogang
Published: August 2023

Theoretical calculations and formula derivation have been used to determine the local work function distribution near the surface of metallic materials.
Modulating the resistive switching stability of HfO2-based RRAM through Gd doping engineering: DFT+U
Authors: Zhang Dong-lan , Wang Jiong , Wu Qing , Du Yong
Published: August 2023

Oxide-based resistive random access memory (RRAM) is standing out in both non-volatile memory and the emerging field of neuromorphic computing, with the consequence of increasing performance demands.
Spin-induced electron transmission through metal–organic chiral crystals
Authors: Kumar Das Tapan , Mondal Amit Kumar , Tiwari Om Shanker , Makam Pandeeswar , Leitus Gregory , Gazit Ehud , Claudio Fontanesi , Naaman Ron
Published: August 2023

Metal–organic Co(ii)-phenylalanine crystals were studied and were found to possess magnetic properties and long-range spin transport.
Tuning catalytic activity with steric and electron-withdrawing effects of a porphyrin substituent
Authors: Jiang Lulu , Imanaka Yosuke , Fujii Hiroshi
Published: August 2023

The reactivity, spectroscopic, and kinetic studies of the catalytic reactions showed that the catalytic activity is determined by the balance of the rates of the formation, reaction, and decomposition reactions of the reactive intermediate.
Ferromagnetically coupled single-chain magnets exhibiting a magnetic hysteresis of 0.42 Tesla in cyano-bridged FeIII2MII (M = Ni, Fe) coordination polymers
Authors: Wang Jin-Hua , Javed Mohammad Khurram , Li Jia-Xin , Zhang Yi-Quan , Li Zhao-Yang , Yamashita Masahiro
Published: August 2023

We report a ferromagnetically coupled [FeIII2NiII] single-chain magnet that exhibits a coercive field of 0.42 T, which is the largest value reported to date among cyano-bridged 3d transition-metal-based single-chain magnets at 1.8 K.
Investigation of in situ sulfide/nitride/phosphide treatments of hematite photoanodes for improved solar water oxidation
Authors: Xing Xiu-Shuang , Zhou Zhongyuan , Song Peilin , Song Xin , Ren Xiaofei , Zhang Daojun , Zeng Xuyang , Guo Yao , Du Jimin
Published: August 2023

Integrating the advantages of in situ sulfide/nitride/phosphide treatments on the surface of a hematite photoanode achieves a remarkably enhanced PEC-WS performance, attributed to the synergistic effect of FeOOH/FeSx and N/P coordination complexes.
Correction: Iridium-(κ2-NSi) catalyzed dehydrogenation of formic acid: effect of auxiliary ligands on the catalytic performance
Authors: Gomez-España Alejandra , Lopez-Morales Jorge L. , Español-Sanchez Belinda , García-Orduña Pilar , Lahoz Fernando J. , Iglesias Manuel , Fernández-Alvarez Francisco J.
Published: August 2023

Correction for ‘Iridium-(κ2-NSi) catalyzed dehydrogenation of formic acid: effect of auxiliary ligands on the catalytic performance’ by Alejandra Gomez-España et al., Dalton Trans., 2023, 52, 6722–6729, https://doi.org/10.1039/d3dt00744h.
Paradoxical role of structural degradation of nickel-rich layered oxides in capacity retention upon storage of lithium-ion batteries
Authors: Hyun Hyejeong , Yoon Hyojung , Choi Subin , Kim Juri , Kim So Young , Regier Tom , Arthur Zachary , Kim SeokKoo , Lim Jongwoo
Published: August 2023

The storage-induced aging mechanism is comprehensively demonstrated. Prolonged idle storage of a Li-ion battery triggered a unique degradation process of layered oxide cathodes, which played a paradoxical role in capacity retention.
Impact of the surface aging of potable water plastic pipes on their lead deposition characteristics
Authors: Hadiuzzaman Md , Ladner David A. , Salehi Maryam
Published: August 2023

The use of plastic potable water pipes to replace corroded metallic plumbing and construct new potable water plumbing systems is rapidly increasing due to the low cost, noncorrosive characteristics, and easy installation of plastic water pipes.
Identification of dietary components in association with abdominal aortic calcification
Authors: Li Wenxiang , Huang Guangyi , Tang Ningning , Lu Peng , Jiang Li , Lv Jian , Qin Yuanjun , Lin Yunru , Xu Fan , Lei Daizai
Published: August 2023

The findings of this study indicate that adopting a dietary pattern characterized by high levels of protein and plant-based foods, as well as reduced levels of fat, may offer potential advantages for the prevention of AAC.
Advancements and challenges in the production of low-carbon fuels via catalytic fast pyrolysis of biomass through refinery integration and co-product generation
Authors: Yung Matthew M. , Mukarakate Calvin , Iisa Kristiina , Wilson A. Nolan , Nimlos Mark R. , Habas Susan E. , Dutta Abhijit , Unocic Kinga A. , Schaidle Joshua A. , Griffin Michael B.
Published: August 2023

Creating pathways to renewable fuels, chemicals, and materials through improved catalyst formulations and integrated process development.
Renewable and water-degradable polyimide-esters from citric acid
Authors: Su Yu-Kai , Short Gabriel N. , Miller Stephen A.
Published: August 2023

Polyimide-esters derived from sustainable citric acid and glycine exhibit commercially-relevant glass transition temperatures and environmentally-relevant water-degradability.
Photoinduced synthesis of C2-linked phosphine oxides via radical difunctionalization of acetylene
Authors: Li Kangkui , Deng Jiazhen , Long Xianyang , Zhu Shifa
Published: August 2023

A photocatalyzed radical difunctionalization of acetylene was achieved, which enables the green synthesis of C2-linked phosphine oxides.
Recent advances in carbohydrate-based gelators
Authors: Tyagi Rajdeep , Singh Kavita , Srivastava Nitin , Sagar Ram
Published: August 2023

This review presented an overview of carbohydrate-based (Glu, Gal, GlcNAc, Rib, Ara) gelators as new materials and their potential applications in various emerging fields such as drug delivery, environmental remediation, antibacterial agents, tissue engineering, thixotropy and wound healing etc.
Dipole moment as the underlying mechanism for enhancing the immobilization of glucose oxidase by ferrocene-chitosan for superior specificity non-invasive glucose sensing
Authors: Ting Jo-Han , Lin Po-Chuan , Gupta Shivam , Liu Ching-Hao , Yang Tzuhsiung , Lee Chi-Young , Lai Yi-Ting , Tai Nyan-Hwa
Published: August 2023

This study showcases the integration of experimental and theoretical approaches for optimizing the biosensor.
Defect-rich carbon-coated nickel–cobalt alloy nanoparticles enhanced the OER catalytic activity through surface reconstruction
Authors: Liu Jiajia , Wang Xiao , Min Yulin , Li Qiaoxia , Xu Qunjie
Published: August 2023

The development of cheap but high activity and strong stability OER electrocatalysts is of great significance to improve electrochemical energy storage and conversion efficiency.
Amine-assisted ionothermal synthesis of in-plane oriented AEL molecular sieve corrosion-resistant coatings
Authors: Wu Wenche , Han Yinuo , Yu Xiaoming , Li Nan , Cao Yuanxin , Chen Qiang , Yu Tongwen
Published: August 2023

An amine-assisted ionothermal strategy for the in-plane oriented molecular sieve coatings with enhanced anti-corrosion performance.
New dinuclear arene Ru(ii) benzilbis(furoylhydrazone) complexes: synthesis, structure, and anticancer activity
Authors: Monika Sankar , Ramesh Rengan
Published: August 2023

Dinuclear Ru(ii) furoylhydrazone complexes are synthesized and characterized. Further, the cytotoxicity of the complexes is explored. The apoptotic cell death pathway is confirmed with aid of AO-EB, DAPI staining and quantified by flow cytometry.
Role of helicity in the nonenzymatic template-directed primer extension of DNA
Authors: Park Sung Joon , Callaghan Kimberley Laura , Ellis Amanda Vera
Published: August 2023

A 2-fold (2AI-dA) and 4.5-fold (2AI-dC) increase in nonenzymatic template-directed primer extension of DNA was observed when a conformational shift was induced by RNA binding.
Emerging functional materials in solid-contact potentiometric sensing, a field full of vitality
Authors: Qu Ke , Li Jinghong
Published: August 2023

A variety of functional materials have been utilized as solid contacts in all-solid-state potentiometric sensors to realize ion-to-electron transduction.
Visible light-mediated syntheses of unsymmetrical methylene-bridged bis-heterocycles via an alkoxy radical relay reaction
Authors: Yuan Ting-Ting , Chen Jing , Pham Le Nhan , Paul Sayan , White Lorenzo V. , Li Jialong , Lan Ping , Coote Michelle L. , Banwell Martin G. , He Yu-Tao
Published: August 2023

Efficient syntheses of unsymmetrical methylene bridged bis-heterocycles have been developed involving light-promoted radical relay reactions.
Facile fabrication of boron and nitrogen co-doped carbon dots for “ON–OFF–ON” fluorescence sensing of Al3+ and F− ions in water samples
Authors: Alqahtani Yahya S. , Mahmoud Ashraf M. , Mahnashi Mater H. , Ali Ramadan , Shahin Reem Y. , El-Wekil Mohamed M. , Batakoushy Hany A.
Published: August 2023

New carbon dots derived from caffeine and boric acid were fabricated for “ON–OFF–ON” determination of aluminum and fluoride. Advantages are simplicity, high quantum yield, and low detection limit.
First-principle computation of some physical properties of half-Heusler compounds for possible thermoelectric applications
Authors: Husain Mudasser , Albalawi Hind , Al Huwayz Maryam , Khan Rajwali , Rahman Nasir
Published: August 2023

Using the density functional theory (DFT) method, we investigate the properties of LaXSi (X = Pt, Pd) half-Heusler compounds.
A novel “turn-off” photoelectrochemical aptasensing platform for selective detection of tobramycin based on the Ti3C2–MoS2/BiOI heterojunction
Authors: Qi Xuejun , Zhao Xing
Published: August 2023

Tobramycin (TOB), as a widely used antibiotic, poses severe unpredictable risks to ecology and health.
Pathway selection by an active droplet
Authors: Dixit Shiva , Chotalia Aarsh , Shukla Shantanu , Roy Tanushree , Parmananda P.
Published: August 2023

Movement of an active 1-pentanol drop within a Y-shaped channel subjected to geometrical and chemical asymmetry is reported. A model is constructed, wherein the particle is subjected to a net force from: Yukawa-like repulsive interaction force, a self-propulsion force, a drag and a stochastic force.
Reaction-driven assembly: controlling changes in membrane topology by reaction cycles
Authors: Häfner Gregor , Müller Marcus
Published: August 2023

Exploring how reaction cycles direct the non-equilibrium self-assembly of amphiphilic molecules into cell-like compartments by computer simulations.
Isolation of hydroxyapatite from Atlantic salmon processing waste using a protease and lipase mixture
Authors: Boudreau Sarah , Hrapovic Sabahudin , Liu Yali , Leung Alfred C. W. , Lam Edmond , Kerton Francesca M.
Published: August 2023

An endoprotease and a lipase were used together for enzymatic treatment of waste salmon frames to produce hydroxyapatite. This environmentally friendly treatment uses mild conditions readily employable in seafood processing plants.
Covalent organic framework derived synthesis of Ru embedded in carbon nitride for hydrogen and oxygen evolution reactions
Authors: Gao Tianyu , Kumar Kilaparthi Sravan , Yan Zhen , Marinova Maya , Trentesaux Martine , Amin Mohammed A. , Szunerits Sabine , Zhou Yong , Martin-Diaconescu Vlad , Paul Sébastien , Boukherroub Rabah , Ordomsky Vitaly
Published: August 2023

Ru embedded in carbon nitride is prepared by pyrolysis of a COF with coordinated RuII for highly efficient HER and OER.
A novel 1D/2D core/shell CdS@SnS2 heterostructure for efficient piezocatalytic hydrogen evolution and pollutant degradation
Authors: Xiong Renzhi , Song Yanjie , Li Kunjiao , Xiao Yanhe , Cheng Baochang , Lei Shuijin
Published: August 2023

A CdS@SnS2 core/shell heterostructure is constructed by in situ growth of SnS2 nanosheets on CdS nanorods for boosting piezocatalytic activity of H2 production and dye degradation.
Achieving a dendrite-free Zn anode at high current densities via in situ polymeric interface design
Authors: Zhong Zhipei , Ren Wenhao , Wang Suqing
Published: August 2023

The Zn5(OH)8Cl2·H2O-doped PAM skeleton is distributed closely and orderly on the surface of the pristine Zn foil, which provides a site for electroplating Zn2+. A part of plated Zn present in the form of “lying flat” on this skeleton. While Zn dendrites grow arbitrarily without additive.
Ammonium fluoride induced barrier-free and oxygen vacancy enhanced LLZO powder for fast interfacial lithium-ion transport in composite solid electrolytes
Authors: Pan Ziwen , Cao Shiyu , Lu Xinqi , Zhang Gang , Shen Qiang , Mao Chong , Dai Xiaobing , Chen Fei
Published: August 2023

Carbonate-free LLZO powder with oxygen vacancies was induced by DMSO solution of NH4F. Composite solid electrolytes with modified powder as a filler exhibit enhanced interfacial lithium-ion transport and an extended electrochemical window.
Distinguishing photo-induced oxygen attack on alkyl chain versus conjugated backbone for alkylthienyl-benzodithiophene (BDTT)-based push–pull polymers
Authors: Anderson Michael A. , Hamstra Anna , Larson Bryon W. , Ratcliff Erin L.
Published: August 2023

The photo-degradation of five push–pull donor polymers depends primarily on kinetically favorable reactions and not redox properties. We present reaction pathways and a methodology for evaluating the light-air stability of photoabsorbing materials.
Continuous wet chemical synthesis of Mo(C,N,O)x as anode materials for Li-ion batteries
Authors: Abdirahman Mohamed Mana , Arnold Stefanie , Janka Oliver , Quade Antje , Schmauch Jörg , Presser Volker , Kickelbick Guido
Published: August 2023

Inorganic–organic hybrid materials synthesized in the microjet reactor by a facile precipitation reaction at room temperature serve as precursors for mixed anionic carbide-nitride-oxides. These materials were used as LIB anode materials.
Revisiting molecularly conformation-planarized organic dyes for NIR-II fluorescence imaging
Authors: An Lei , Zheng Liangyu , Zhao Ziqi , Qu Xinyu , liang Chen , Ou Changjin , Mou Xiaozhou , Dong Xiaochen , Cai Yu
Published: August 2023

Conformation-planarized NIR-II dyes were developed to prolong the maximum absorption wavelength over 950 nm and maintain high fluorescence efficiency of 2% in nanoparticles.
Magnetic and electrical bistability in hybrid composites of conducting organic polymers with [Fe(NH2-trz)3]n[SO4]n
Authors: Nieto-Castro David , Graf Anna Weronika , Gispert-Guirado Francesc , Galán-Mascarós José Ramón
Published: August 2023

Spin crossover (SCO) materials are potential building blocks for multifunctional hybrids. Mechanochemical processing appears as a promising tool to achieve bistable conducting composites with synergic magnetic and electrical bistability.
High-loading ultrastable CsPbBr3 perovskite quantum dots in hierarchical silicalite-1 by elimination of co-templates for multimodal optical applications
Authors: Yu Xiandi , Zhang Yuchi , Han Le , Xu Yan
Published: August 2023

Hierarchical silicalite-1 co-templated by carbon nanotube and tetrapropylammonium hydroxide was used to confine CsPbBr3 PQDs, showing multiple functions for optical thermometry, fingerprint identification, Fe3+ detection and anti-counterfeiting.
Perceptual Assessment of Cleft Palate Speech—Bridging the Gap From Research to Clinical Practice—the Swedish Perspective
Authors: Klintö Kristina , Lohmander Anette
Published: August 2023

Purpose:

The purpose of this tutorial is to describe an evidence-based scientifically sustainable perceptual assessment of cleft palate speech and how standardized assessment methods for research on cleft palate speech have been implemented in clinical practice in Sweden, which makes it possible to carry out research on clinical data.

Method:

This tutorial is based on a literature review and own research on how to perform a valid and reliable perceptual cleft palate speech assessment and the description of clinical practice in Sweden. Perceptual speech assessment of cleft palate speech is discussed in terms of speech material, documentation, perceptual speech analysis, speech outcome measures, cross-linguistic comparisons, calculation of reliability, interpretation of results, and subject selection. We also describe the conditions that have made it possible to integrate research and clinic in cleft palate speech-language pathology in Sweden.

Conclusions:

Knowledge acquired from national and international research has had a great impact on the development of cleft palate speech assessment procedures in Sweden and has contributed to standardized evaluation of treatment results. This has enabled open comparisons of treatment results from the different Swedish cleft lip and palate (CLP) centers to provide a basis for improved CLP care.
Uncertainty‐aware iterative learning for noisy‐labeled medical image segmentation
Authors: Hao Pengyi , Shi Kangjian , Tian Shuyuan , Wu Fuli
Published: August 2023

Medical image segmentation from noisy labels is an important task since obtaining high‐quality annotations is extremely difficult and expensive. There are a lot of approaches proposed for such task. However, some issues like the overfitting on noisy annotations, the limited learning of boundary features, and no consideration of the corrupted local pixels are still not solved. Therefore, a novel approach named uncertainty‐aware iterative learning (UaIL) is proposed for medical image segmentation with noisy labels. UaIL iteratively and jointly trains two deep networks using the original images and their argumented ones through a joint loss function including softened label loss, hard label loss and consistency loss, which encourages UaIL to produce segmentations that are robust to the perturbations in arbitrary semantic space. The uncertainty of labels is estimated based on the predictions in iterative learning, then the original labels are refined, which improves the learning of boundary features in segmentation. To avoid overfitting, a stopping strategy is designed based on the dice coefficient in iterative learning. Experiments on two public datasets verify the effectiveness of UaIL under different levels of annotation noise. Especially, when there are serious noises in the labels, the dice achieved by UaIL is 1.43% to 15.03% higher than the competing approaches on the two public datasets. The UaIL is further verified on a private dataset, which shows its ability of applying in the real application with noisy labels.
Tensor surface impedance modelling of metasurfaces with printed elements
Authors: Shavit Reuven , Tzabari Yarden
Published: August 2023

Two methods for extraction of the effective tensor surface impedance representing metasurfaces with printed elements and arbitrary geometry are presented. The surface impedance can be modelled as a shunt admittance on a transmission line. The extracted surface impedance combined with transmission line theory enables to compute easily and efficiently the transmission coefficient through a multilayer metasurface structure. The metasurface modelling as a shunt admittance enables to conduct a multi‐parameter study on the transmission and reflection performance through the metasurface structure. The results of the proposed methods are compared, and very good agreement was obtained up to 30° incident angle. Beyond 30° it is suggested to recalibrate the model or upgrade it. For model validation purposes, a 2D flat lens antenna with patch elements loaded with capacitors was designed, fabricated, and measured. Simulation and experimental results of the lens near and far‐field are presented.
Ultraviolet electronic spectroscopy of heavily substituted naphthalene derivatives
Authors: Fréreux J. N. , Godard M. , Dartois E. , Pino T.
Published: August 2023

Context. The so-called bump spectral signature observable on interstellar extinction curves, peaking at 217.5 nm, is commonly assigned to π* ← π transitions from carbonaceous carriers, but the exact nature of the carbonaceous carriers remains debated.

Aims. To constrain the chemical structures associated with the bump carriers, we record and compare the UV spectra of a large variety of carbonaceous molecules to this interstellar feature.

Methods. Large carbonaceous molecules, such as polycyclic aromatic hydrocarbons (PAHs), were produced by a combustion process stabilized at low pressure under rich flame conditions. Species were extracted and probed through resonance enhanced multiphoton ionization spectroscopy coupled to a time-of-flight mass spectrometer. Masses and absorption profiles of the carbonaceous molecules were measured, and their spectra were compared to the bump feature.

Results. Species showing a specific mass progression starting at mass 128 u visible up to mass 394 u with a characteristic progression of +14 u present a common electronic absorption band profile peaking asymptotically around 220 nm. The first masses were assigned to a naphthalene C10H8 molecule and two of its derivatives: C10H7CH3 and C10H7C2H5. The mass progression of +14 u is explained by successive H atom substitutions by CH3 functional groups. This mass distribution was thus assigned to naphthalene derivatives with large aliphatic carbon substitution. This derivative family shows an electronic band assigned to S3 ← S0 transitions involving electron promotion within the π aromatic orbitals of the naphathlene chromophore. More importantly, after a few substitutions, the position of the band converges asymptotically to a value close to the interstellar bump signature, independent of the molecule size.

Conclusions. Based on the asymptotic behavior of the larger members in the species distribution, a similar band position is expected from double aromatic ring substructures within hydrogenated amorphous carbons (HACs). Similar to the conclusions of previous works, we find substituted naphthalene units as substructures of interstellar HACs to be good candidates as carriers of the bump feature.
3D Stagger model atmospheres with FreeEOS
Authors: Zhou Yixiao , Amarsi Anish M. , Aguirre Børsen-Koch Victor , Karlsmose Klara G. , Collet Remo , Nordlander Thomas
Published: August 2023

Three-dimensional radiation-hydrodynamics (3D RHD) simulations of stellar surface convection provide valuable insights into many problems in solar and stellar physics. However, almost all 3D near-surface convection simulations to date are based on solar-scaled chemical compositions, which limits their relevance when applied to stars with peculiar abundance patterns. To overcome this difficulty, we implement the robust and widely used FreeEOS equation of state and our Blue opacity package into the Stagger 3D radiation-magnetohydrodynamics code. We present a new 3D RHD model of the solar atmosphere, and demonstrate that the mean stratification as well as the distributions of key physical quantities are in good agreement with those of the latest Stagger solar model atmosphere. The new model is further validated by comparisons with solar observations. The new model atmospheres reproduce the observed flux spectrum, continuum centre-to-limb variation, and hydrogen line profiles at a satisfactory level, thereby confirming the realism of the model and the underlying input physics. These implementations open the prospect for studying other stars with different α-element abundance, carbon-enhanced metal-poor stars, and population II stars with peculiar chemical compositions using 3D Stagger model atmospheres.
The star formation history of the Sco-Cen association
Authors: Ratzenböck Sebastian , Großschedl Josefa E. , Alves João , Miret-Roig Núria , Bomze Immanuel , Forbes John , Goodman Alyssa , Hacar Álvaro , Lin Doug , Meingast Stefan , Möller Torsten , Piecka Martin , Posch Laura , Rottensteiner Alena , Swiggum Cameren , Zucker Catherine
Published: August 2023

We reconstructed the star formation history of the Sco-Cen OB association using a novel high-resolution age map of the region. We developed an approach to produce robust ages for Sco-Cen’s recently identified 37 stellar clusters using the SigMA algorithm. The Sco-Cen star formation timeline reveals four periods of enhanced star formation activity, or bursts, remarkably separated by about 5 Myr. Of these, the second burst, which occurred about 15 million years ago, is by far the dominant one, and most of Sco-Cen’s stars and clusters were in place by the end of this burst. The formation of stars and clusters in Sco-Cen is correlated but not linearly, implying that more stars were formed per cluster during the peak of the star formation rate. Most of the clusters that are large enough to have supernova precursors were formed during the second burst around 15 Myr ago. Star and cluster formation activity has been continuously declining since then. We have clear evidence that Sco-Cen formed from the inside out and that it contains 100-pc long chains of contiguous clusters exhibiting well-defined age gradients, from massive older clusters to smaller young clusters. These observables suggest an important role for feedback in forming about half of Sco-Cen stars, although follow-up work is needed to quantify this statement. Finally, we confirm that the Upper-Sco age controversy discussed in the literature during the last decades is solved: the nine clusters previously lumped together as Upper-Sco, a benchmark region for planet formation studies, exhibit a wide range of ages from 3 to 19 Myr.
Hydraulic parameters of well of Pskom hydroelectric power plant in Uzbekistan
Authors: Sharopov Sharifjon , Abduraimov Abdulaziz , Donoboyev Jumaniyoz , Ostyakova Aleksandra
Published: August 2023

In arid regions, the construction of hydraulic structures is relevant due to the shortage of water resources. Using the example of the Pskov hydroelectric power station, the results of the hydraulic calculation of the end structure of the energy spillway, made in the form of a water well of a unique design, are presented. A culvert wall, made with an initial expanding part and a sloping spillway part forming an oblique spillway, forms the well. The depths and speeds in each part of the water well and the parameters of the hydraulic jump are calculated. It is shown how significant damping of the water flow energy occurs in the selected water well design. The water velocity at the outlet of the water well becomes less eroded, decreasing several times. The critical depth is calculated when the width of the stream changes, the depth of water in the waterhole, the pressure on the waterhole wall, the height of the waterhole wall located along the spillway face of variable width, the interface of the water flows behind the waterhole wall.
Transport capacity of flow in earthline channels
Authors: Arifjanov Aybek , Samiyev Luqmon , Xoshimov Sardor , Shaymardanov Samandar , Tadjiboyev Suhrob
Published: August 2023

The theory of river flow transport is the major cause of the development of the irrigation sector and largely determines the stability of the irrigation scheme. Crop water requirements vary due to climate and crop growth stages. For this reason, the flow of sediments changes during the irrigation season. In this article, to evaluate the canals’ carrying capacity, research in natural field conditions was carried out in the Amuzang canal belonging to the “Amu-Surkhan Irrigation Systems” basin administration. Flow transportability in natural channels was calculated for particles with d=0.05 mm by S.Kh.Abalyans, A.Zamarin, A.M.Arifzhanov, and Engelund and Hansen methods. A histogram of the dependence of flow capacity, channel depth, and average speed on the Amuzang channel was obtained, according to which it was determined that the flow capacity is 1.5-1.8 kg/m3in the range of 0.6-0.8 m/s.
Practice of permanent presence and equipment of Karshi main canal
Authors: Glovatskiy Oleg , Ergashev Rustam , Kurbonov Ilhom , Kholbutaev Boybek , Pirnazarov Ilkhom , Rajabov Adkhamjon
Published: August 2023

The research aims to develop new energy-saving modes of operation of the Karshi main canal with a cascade of pumping stations designed to irrigate the virgin lands of the Karshi steppe with water from the Amudarya River. The article discusses some calculation methods and control parametric tests of pumps by measuring the main parameters: flow, pump head, electric motor power, NPSH, and pump efficiency. Normal operation of pumping stations requires compliance with cavitation conditions of pumps of certain levels downstream. The authors have given recommendations on the use of a new floodwater design and obtained the flow's main characteristics in the section under consideration, taking into account the hydrometric characteristics. Further work continues to improve the scheme of water supply facilities by introducing new means of regulating the operation of pumping station elements into the scheme.
Simulation testing of traffic flow delays in bus stop zone
Authors: Dashdamirov Fuad , Abdurrazzokov Umidulla , Ziyaev Kamoliddin , Verdiyev Turan , Javadli Ulvi
Published: August 2023

Traffic flows are subject to certain delays due to the maneuvering of buses entering and leaving the stop. The study of how these delays change depending on the frequency of arrival of buses to a stop and, the change of lanes on the road, the intensity of the traffic flow on the road is important in organizing traffic and planning the movement of buses along the route. The article uses simulation models built in the PTV VISSIM program to estimate the delay time of the traffic flow on 2, 3, and 4 lane roads for 4 different values of the intensity of the traffic flow and 5 different values of the bus arrival frequency at the stop. The results obtained are analyzed. The changing nature of traffic flow delays in various scenarios has been studied.
Correction of ted field weakening switching diagram for mainline diesel locomotives of te type
Authors: Djanikulov A. T. , Safarov U. I.
Published: August 2023

The processes are considered when the stages of weakening of the TED magnetic field are switched on on diesel locomotives of the TE10 type. The analysis of the unstable operation and automatic switching on of the transition relay at partial loads corresponding to the locomotive's speed at the rated load in operation is carried out. TED current algorithms are proposed for correcting the scheme for switching on the relay of transitions from a full field to a weakened field. A variant of the correction circuit is proposed to check its operation during operation. This principle has been violated since the creation of the TE10 diesel locomotive. It is still violated on TE10 diesel locomotives, except for diesel locomotives equipped with the USTA system.
Shear oscillations of bridge on sliding foundation during earthquake
Authors: Mirzaev Ibrakhim , Askarova Dilbarkhon , Turdiev Malikjon , Shomurodov Jakhongir
Published: August 2023

The article investigates the vibration of the railway bridge on the sliding foundation with dry friction under the action of real earthquake records at the intensity of 7, 8, 9, and over 9 on the MSK-64 scale. Dynamic dry friction problems are non-linear since each slip's start and end times are determined during the problem-solving process; they depend on many design parameters and external influences. The simplified model of vertical and shear deformation of the bridge is proposed as oscillating intermediate support with the mass of the span connected to the girth rail by a rubber bearing part. In this case, all elements in the structural model are connected to each other, taking into account eccentricities. The finite element method discretizes the coordinate variables and the Newmark time method with matrices built at each step. Structural vibrations are studied based on four real earthquake records. It is shown that using a sliding foundation can significantly reduce the shear forces in the bridge supports depending on the structure mass, the dry friction coefficient, and the nature of the seismic effect.
Substantiation of actual and forecast reclamation situation in assessing effectiveness of artificial drainage in irrigated areas in management of water resources
Authors: Amanov Bakhodirjon
Published: August 2023

In the context of this work, when evaluating the effectiveness of artificial drains on irrigated lands in modern conditions, irrigation networks, reclamation regime, irrigation, salt washing, drainage, agricultural technology (not considered here), and land use in a specific composition and high flow rates, as well as one-dimensional differential equations that provide the necessary water-salt regimes by substantiating the actual and predicted reclamation state using the WASTER computer program. The amount of drainage is taken from the methodology of the water-salt balance of the Research Institute of Irrigation and Water Problems (RIIWP) and is set in the WASTER computer program. For example, artificial drainage was used on irrigated lands in the Pakhtakor district of the Jizzakh region. Irrigation regimes and rates are considered in 2 variants, considering drainage in the WASTER computer program for these areas. These models take into account the absorption of moisture and salts from the soil into the root layer of the plant, taking into account the work of artificial drainage in boundary conditions. The calculated criteria for each option are compared and analyzed. In addition, the volumetric moisture content and salinity are observed and analyzed in the layers. In addition, we considered the experiments and methods carried out by other scientists.
Ore-containing data of lyalyagun mineralized zone of malguzar mountains
Authors: Abdullaev Abror , Khaliyorov Kholmurod , Shanazarov Sunnat , Ziyayeva Paraxat , Ruziyev Ilkhom , Muminov Mahmud
Published: August 2023

An analysis of the Malguzar Mountains allows us to note that Silurian formations (sandstones, gravestones, shale) are ore-bearing here, crumpled into folds, which are complicated by a series of faults with a northwest strike. These structures are rectilinear; their zone is characterized by the presence of small discontinuous structures and areas of swelling. Within the Lyalyagun zone, the localization sites of mineralized zones of gold mineralization were identified based on established direct and indirect cosmogeological features.
Charvak reservoir modeling based on geoinformation systems
Authors: Ikramova M. , Umarova Sh. , Ahmedkhodjaeva I. , Akhmedkhodjaeva K.
Published: August 2023

The article describes the Charvak reservoir morphological map development, created using the softs capable of processing, analyzing, and visualizing high-resolution satellite geodata. The study determined the amount of useful volume change during the reservoir's operation. The map was designed to be interactive and processed in real time using GoogleEarth and ArchGIS analytical tools. The study aims to improve effective monitoring of the changes in water reservoir capacity and forecasting the further operational period of the reservoir. The research demonstrates the potential of geoinformation technologies to improve water resources management.
Modeling release and distribution of harmful substances in river
Authors: Muhamediyeva Dilnoz , Khujaev Otabek
Published: August 2023

The development and analysis of a computational algorithm for mathematical models of the release and spread of harmful substances is an important area of research that can help mitigate the impact of pollution on the environment and human health. Mathematical models of the distribution of harmful substances in the river are useful for predicting the spread of pollutants and identifying potential environmental and public health risks. The computational algorithm for the problem of diffusion of harmful substances can help researchers and policymakers to understand the mechanisms of pollutant dispersion and identify effective strategies for mitigating the impact of pollution. The algorithm can simulate the release and spread of harmful substances in various scenarios, including accidental spills, industrial discharges, and natural disasters. The results of a computational experiment can provide valuable insights into the behavior of pollutants in different environmental conditions and help identify potential risks and areas of concern. By analyzing the results of a computational experiment, researchers can develop effective strategies for managing and mitigating the impact of pollution on the environment and public health.