bluuebunny/crossref_metadata_2025 huggingface dataset:
De novo Ser72Leu mutation in the peripheral myelin protein 22 in two Polish patients with a severe form of Charcot-Marie-Tooth disease.
Authors: Kochański Andrzej , Kabzińska Dagmara
Published: December 2024

To date, 12 cases of heterozygous Ser72Leu mutations in the peripheral myelin protein 22 have been reported in patients suffering from severe demyelinating form of Charcot-Marie-Tooth disease (CMT1) and congenital hypomyelinating neuropathy (CHN) [MIM# 605253]. In the present study we report two cases of de novo S72L mutations in the PMP22 gene detected in patients of Polish origin suffering from CMT1 disease.
An Effective Hybrid Feature Selection Method Based on an Improved Artificial GTO Algorithm for Medical Datasets
Authors: Saabia Abd Al-Baset Rashed , Frikha Mondher
Published: December 2024

Feature subset selection is considered as the most essential pre-processing step. Metaheuristic approaches may be employed to discover a solution to difficulties in feature selection, which can be viewed as an optimisation problem. The aim of the system is to provide a hybrid binary metaheuristic algorithm that combines gorilla troop optimisation and genetic algorithm to handle the feature selection issue effectively. This new method is called GTO-GA. To ensure that the optimisation technique converges fast and properly and to enhance the exploration process, the GA were used. The suggested technique is tested for stability and robustness using 16 medical datasets taken from the Kaggle and UCI repositories. To evaluate the chosen features’ performance in classification issues further. The results show that the algorithm outperforms 10 top-tier optimisation methods, including PSO, ALO, the original GTO and the SCA algorithm. The results highlighted the statistical difference, superiority and importance of the suggested feature selection strategies.
Applications of Generative Artificial Intelligence in the Software Industry
Authors: Damyanov Ivo , Tsankov Nikolay , Nedyalkov Iliya
Published: December 2024

The increasing demands on software development are putting serious pressure on its pace. To assist software developers, an increasing number of tools powered by generative artificial intelligence are being introduced. This paper aims to investigate how the use and integration of generative AI have evolved among professionals in the software industry, based on a study involving 104 individuals working in Bulgarian software companies. Data was collected in April 2024 through an online questionnaire with four separate groups of questions related to the use of generative AI at work. The study found that 2/3 of the respondents use generative AI actively in their daily work. They highly value the practical benefits of this type of technology, which most often consist of automating routine activities, accessing information quickly, generating initial code, and writing documentation. As a result of these benefits, developers are increasingly moving towards using generative AI at the expense of professional support platforms. The main benefits they cite include faster solutions, more specific and relevant answers, and significantly shorter time to reach the desired outcome.
Proposed Approach for Overcoming the Impact of Unbalanced Distribution in Predicting Students' Performance
Authors: Dimić Gabrijela , Pecić Ljiljana
Published: December 2024

The paper presents a method for mitigating the impact of an unbalanced distribution of multidimensional class features on grade prediction accuracy. For the purposes of the case study, an educational data set named APOD was created by integrating data from heterogeneous sources. The input features and the multidimensional class feature were defined. The effectiveness of adopting the Synthetic Minority Over-Sampling Technique (SMOTE) to handle data imbalance issues was explored using various classification methods. To determine which algorithm performed best in terms of minority class distribution, three experiments were carried out. The SMOTE approach with automatic minority class detection and a 100% sampling factor demonstrated a considerable improvement in model performance for four out of five classifiers that were tested. The primary objective of the study described in this paper is to address the problem of predicting students' final grades in situations where a small dataset causes data imbalance. Small datasets provide insufficient representation of instances within specific classes, resulting in unreliable models with poor performance in predicting student success. The proposed approach for implementing SMOTE is based on an algorithm for identifying minority classes, with a predetermined minimum number of samples per class. This approach enables the development of precise models for predicting students' final test results, even with small educational datasets. The contribution of the proposed research lies in achieving greater accuracy in predicting students' final grades, regardless of dataset size and the presence of minority classes.
Analysis of Robotic Joints` Motion for Dental Handling Operations Using RoboDK Simulator
Authors: Duplák Ján , Dupláková Darina , Yeromina Maryna , Mikuláško Samuel
Published: December 2024

Industrial automation and robotics are currently a strong field of engineering that is continuously developing and bringing with it significant technological advances. As information technology advances, so too do the processes using elements of this industry, helping to increase both productivity and efficiency. In the creation of robotic environments, simulation tools are used in the design phase through which all the necessary tasks, layouts can be created in detail while minimizing time and financial resources. Currently, the robotic simulator tools market is expanding, which brings with it the solution of several application decisions. The decisionmaking focuses on determining the appropriate simulator with a wide range of capabilities for simulating handling operations in the process of different types of manufacturing. This paper focuses on the study, analysis and testing of a robotic simulator that could be implemented in the context of dental manufacturing, which has several specificities associated with it. RoboDK software was reviewed as part of the study. After creating a model corresponding to a real workplace, analysis plots of the movements of the robot's joints and gripper during manipulation operations were created.
Detection of Digital Currency Fraud through a Distributed Database Approach and Machine Learning Model
Authors: Abdiwi Faisal Ghazi
Published: December 2024

The world is witnessing a noticeable increase in financial exchange in digital currencies such as Bitcoin, Ethereum, and others, as transactions in electronic markets have begun to rise recently, which increases the difficulty of maintaining security and trust in decentralized financial systems that use distributed databases and the technologies that interact with them in Ethereum networks, blockchain, etc. This study presents a hybrid model based on the PyCaret library and includes 12 machine learning classifiers, with the aim of identifying fraudulent activities in Bitcoin transactions and enhancing the security of Ethereum networks and blockchain technology. The results reveal the effectiveness of different models in identifying fraudulent activities on the Ethereum network through a comprehensive performance comparison. The classifiers that showed the highest accuracy scores, which ranged from 0.9814 to 0.9862, were the Random Forest classifier, the visual gradient boosting machine, and the additive tree classifier. It is important to note that both Gradient Boosting Classifier and K Neighbors Classifier performed well, with accuracies above 0.96 and AUC scores above 0.99. However, some models, such as Naive Bayes, showed lower accuracy and AUC scores, suggesting that they have limitations in terms of accurately detecting fraudulent transactions. These results highlight the importance of choosing appropriate machine learning models for fraud detection tasks in general, with ensemble techniques such as Extra Trees and Random Forest showing great promise in this regard.
A Bibliometric Analysis of Women’s Entrepreneurship to Sustainable Economic Growth
Authors: Ma’ruf Aminudin , Chalifatunnisa Cut Meutia , Nabila Nevinda Salsa
Published: December 2024

Towards economic development, women have the right to maximise their potential to achieve economic growth. This study aims to analyse research trends that can develop and provide implications for women's business empowerment. The outline literature published between 2000 and 2020 adopted bibliometric indicators and a literature review approach to visualise research developments and see opportunities to improve studies on women's entrepreneurship. A total of 317 research articles were generated based on keywords from the Scopus database. The study shows a process of empowering women to increase the potential complicity of women entrepreneurs in entrepreneurial activities. In this case, the suitable activities are from SMEs, which are HBBs (Home-based businesses). The paper humbly encourages future research to explore more on the topic of women’s entrepreneurship following its untapped potential. Consequently, the analysishighlighted some areas of the study in the field of women’s entrepreneurship, motivating future research. This study is expected to motivate the government, economic activists, and researchers to delveinto the potential of women’s entrepreneurship to strengthen the economy.
Evaluation of Free Software Use in Learning Environments
Authors: Piñón-Howlet Laura Cristina , Sapién-Aguilar Alma Lilia , Chávez-Acosta Humberto
Published: December 2024

Open-source software in the educational field aims to contribute to rethinking a different learning strategy model. The goal was to assess whether the use of open-source software can contribute to improving learning environments in a higher secondary education institution in Mexico. A quantitative, non-experimental, transactional, descriptive, and correlational research method was employed. The results showed that open-source software is a valuable support in developing new didactic strategies. The findings revealed confidence among teachers in using open-source software as a didactic strategy, and students considered starting to use open-source software from the first semesters. This research is original as open-source software supports the development of new didactic strategies. The limitation was that teachers use proprietary software, and it is likely more challenging for them to use opensource software.
Five to Five: Sex-Disaggregated Issues in Bicol Region (V), Philippines Through the Lens of SDG 5
Authors: Rañon Dennis N.
Published: December 2024

The paper examines the sex-disgregated issues affecting men and women in Bicol Region (5), Philippines, through the lens of Sustainable Development Goals (SDG 5) indicators. Utilizing qualitative-evaluative research methodologies such as comparative data analysis and documentary analysis, the study analyzes data from various government agencies to identify persistent gender disparities in labor market participation, health, and political representation. Findings revealed that significant challenges remain unsolved despite gradual improvements in women's engagement in public life, including cultural barriers, income inequalities, and limited access to leadership roles. The paper emphasizes the necessity of generating sex-disaggregated data to inform policy-making and recommends that Local Government Units, NGOs, and private sectors institutionalize SDG localization to address identified issues effectively. The study also advocates for inclusive policies that promote gender equality and enhance women's societal roles, contributing to a more equitable and harmonious society.
Control Disciplinario en las Policías de (La Ciudad y la Provincia de) Buenos Aires. Un análisis jurídico de su sistema disciplinario policial
Authors: Laguian Rodrigo H.
Published: December 2024

En este artículo efectuaremos un análisis jurídico de las normas que regulan el régimen disciplinario aplicable en las policías de la Ciudad y la Provincia de Buenos Aires; previo a ello, y en primer lugar, esbozaremos aquellos antecedentes que permitieron la creación tanto de la Policía de la Provincia de Buenos Aires como de la Policía de la Ciudad de Buenos Aires. Ello nos permitirá adentrarnos a desarrollar el sistema disciplinario de cada una de estas agencias policiales, aplicados por la Auditoría General de Asuntos Internos (en el caso de la Policía de la Provincia) y por la Oficina de Transpa­rencia y Control Externo (en el caso de Policía de la Ciudad). En ese marco, abordaremos los antecedentes previos (fácticos y normativos) que posibilitaron la creación de estos órganos civiles de control en lo disciplinario policial, así como también sus funciones, composición, dependencia jerárquica y estructura interna (organigrama).
Finalmente, analizaremos el procedimiento administrativo sumarial que se aplica en cada una de estas instituciones policiales, especificando qué autoridades se encuentran facultadas para investigar y sancionar al personal involucrado, qué sanciones les corresponderían en cada caso y cuáles son los recursos adminis­trativos que pueden interponer. Culminaremos el presente trabajo acercando algunas reflexiones finales.
Cuba y la República de Corea. Del reconocimiento del Estado a las relaciones diplomáticas (1949-2024)
Authors: González Saez Ruvislei
Published: December 2024

Cuba fue el último país en establecer las relaciones diplomáticas con la República de Corea, el 14 de febrero de 2024; sin embar­go, fue el primer país de América Latina y el Caribe en reconocer a la nación asiática, antes que Brasil, que también lo hizo en 1949. La no evidencia física de los momen­tos en que se establecieron oficialmente los lazos diplomáticos el 12 de julio de 1949, y la ruptura (probable cese de facto por reconocimiento de la República Popular Democrática de Corea) tras el triunfo de la Revolución Cubana en 1959 llevaron a evaluar el término establecimiento y no restablecimiento en el año 2024 por las dos naciones. Justamente, el año 2024 marca el 75 aniversario del reconocimiento oficial de la República de Cuba por parte de la República de Corea y el inicio de los vínculos diplomáticos bilaterales.
El artículo se propone explicar la evolución de las rela­ciones entre las dos naciones, desconocida en su mayoría y que ha sido resultado de una investigación profunda iniciada en el año 2022. En este sentido, algunos de los elementos que se publicarán en este artículo serán socializados académicamente por pri­mera vez, mientras otros ya han sido previa­mente publicados por el autor en artículos en la República de Corea. Los dos países, en sus históricos vínculos, tienen la pecu­liaridad de nunca haber tenido diferencias bilaterales, sobre la base de los históricos lazos que se abrirán hacia una nueva etapa.
Cirurgias plásticas na Coreia do Sul: a perspectiva da Teoria Feminista das Relações Internacionais
Authors: Carvalho Sertori Beatriz , Silva Geraldello Camilla
Published: December 2024

El fenómeno de la cirugía plástica ha aumentado a nivel mundial, este aumento puede atribuirse a la creciente presión que enfrentan las personas debido a los están­dares de belleza actuales. En este sentido, Corea del Sur es considerada líder mundial en procedimientos quirúrgicos, debido a su popularidad y normalización dentro de la sociedad surcoreana. La apariencia externa es de gran importancia cultural en Corea del Sur, especialmente para un grupo some­tido a las normas de belleza más rígidas: las mujeres. Este artículo pretende comprender la construcción del estándar de belleza occi­dental y cómo se fusiona en la cultura surco­reana. De esta manera, la Teoría Feminista de las Relaciones Internacionales, junto con el sesgo decolonial, operará como una “lente” para investigar cómo esta norma de belleza controla y limita la imagen de la mujer en una sociedad patriarcal. Además, esta investigación también busca cuestio­nar el estándar de belleza internacional, basado exclusivamente en rasgos europeos, que se ha propagado globalmente como el arquetipo de belleza. Este fenómeno tiene consecuencias tremendas para las mujeres, sobre todo para aquellas que no se ajustan a este estándar occidental, e impacta negati­vamente en la formación de sus identidades. En última instancia, las mujeres surcorea­nas experimentan las crecientes presiones impuestas por los estándares occidentales, lo que las predispone a someterse a proce­dimientos quirúrgicos.
Viðmerking: Mannarættindi og heimspekiligar avbjóðingar
Authors: Hansen Jógvan Dalbø
Published: December 2024

The idea that human beings have some fundamental rights goes back a long way in the history of philosophy. But the justifications for these rights have been quite different. The question has also been raised whether these rights are inherent or to be regarded as consensus among men. There can be no final agreement on these questions. At the same time, however, it is a proven fact that the concept of human rights plays an important role in both domestic and international legal understanding. The article describes some of these issues.
Úrtak
Hugsanin um, at menniskjað hevur nøkur grundleggjandi rættini, gongur langt aftur í heimspekisøguna. Men grundgevingarnar fyri hesum rættindum hava verið rættiliga ymiskar. Spurningur hevur eisini verið settur við, um hesi rættindi eru íborin ella at meta sum samtykt manna millum. Ikki kann sigast, at nøkur endalig semja er um hesar spurningar. Men samstundis er tað ein royndur lutur, at mannarættindahugtakið hevur ein týðandi leiklut bæði í heimligari og altjóða rættarfatan. Greinin lýsir nøkur av hesum viðurskiftum.
"The Faroe Islands handle this themselves”: The convergence of bodily and national autonomy in abortion rights discussions
Authors: Nolsøe Turið , Hermannsdóttir Turið
Published: December 2024

Faroese abortion legislation is subject to CEDAW’s (Convention on the Elimination of All Forms of Discrimination against Women)  regular reports and has in the last two decades faced criticism for its failure to secure sufficient abortion rights. In this article we analyse international deliberation of the Faroese abortion legislation, where national autonomy as an ideal seemingly outweighs the right to bodily autonomy as a human right. Conducting a concept-oriented critique of how abortion rights are discussed in the convergence of these discourses of autonomy, we emphasise the limitations of arguing for bodily autonomy in relation to abortion rights as a human right. But we also argue that the rhetorical performance of statehood should be scrutinised when it reflects a problematic conception of the right to self-government where national statehood trumps reproductive citizenship. Rather than deliberating the circumstances under which reproductive rights are managed in the Faroe Islands, international attention to the Faroese case becomes an opportunity to underscore that “the Faroe Islands handle this themselves". This article sheds light on both the foundation underpinning a human rights perspective on abortion rights and on the Faroese situation.
Úrtak
Viðkomandi føroysk viðurskifti vera viðgjørd í frágreiðingunum hjá CEDAW (Convention on the Elimination of All Forms of Discrimination against Women) um danska kongaríkið og føroyska abortlóggávan hevur sostatt seinastu tvey áratíggjuni fingið ábreiðslu fyri ikki at tryggja abortrættindi í nøktandi mun. Í hesi grein greina vit altjóða viðgerðina av føroysku abortlóggávuni og hvussu tjóðskaparligt sjálvræði sum ideal verður sett hægri enn kropsligt sjálvræði sum menniskjarættindi. Gjøgnum eina hugtakslýsing av hvussu abort verður viðgjørt í hesi samanrenning av sjálvræðisdiskursum, leggja vit dent á hvørjar avmarkingar eru í samband við at grundgeva fyri nær abortrættindi eru menniskjarættindi. Men grundgivið verður eisini fyri hvussu retoriska framførslan av fullveldisstøðu Føroya vísir eina ivingarsama fatan av rættinum til sjálvstýri har tjóðskaparligt sjálvræåi vinnur á reproduktivum medborgaraskapi: heldur enn at viðgera hvussu reproduktiv rættindi verða tryggjað í Føroyum, so verða altjóða ábreiðslur nýttar sum høvi at undirstrika at “Føroyar taka sær av hesum sjálvar”. Sostatt lýsir greinin bæði grundarlagið undir menniskjarættindaatlitum til abort umframt føroysku støðuna.
CHARACTERIZATION AND EVALUATION OF THE ANTIOXIDANT POTENTIAL OF PUMPKIN SEED FLOUR (CUCURBITA MOSCHATA)
Authors: Oliveira Cristiane , Almeida Castro Pagani Alessandra , SILVA BORGES Ângela , BELTRÃO LESSA CONSTANT Patricia
Published: December 2024

The food industry is looking for more efficient alternatives to avoid lipid oxidation, changes in color and flavor, due to losses in the quality of food products, especially meat derivatives. The use of antioxidants is the most used way to prevent lipid oxidation in foods. Pumpkin seed flour (Cucurbita moschata) has antioxidant properties due to the presence of tocopherols (vitamin E), mainly in the form of tocopherol and alpha-tocopherol isomers, and is rich in fiber, proteins, polyunsaturated fatty acids and mineral salts. Aiming to study sources of natural antioxidants as an alternative to replace the synthetic antioxidants commonly used by the industry, this study aimed to characterize, evaluate the compounds present by the FTIR method and evaluate the storage time on the antioxidant potential of pumpkin seed flour (Cucurbita moschata) using the ABTS method. The seeds were stored at -18°C for 4 and 24 days before processing, subjected to the cleaning process, drying in a pardal dehydrator, and crushed to obtain flour. The values ​​for antioxidant potential by the ABTS method showed average values ​​of 475 µmol eq. trolox/g. Storage time did not influence the antioxidant potential of the flour and the results demonstrate that pumpkin seed flour has the potential to be used and contribute to the use of waste by the industry, reducing pollution caused by this waste.
THE IMPLEMENTATION OF CLOUD PHONE TELEPHONE SYSTEMS, MPLS INTERNET AND SERVER VIRTUALIZATION IN THE GOVERNMENT SECTOR OF IBIÁ
Authors: Silva Cristiano Silveira , Medeiros Martins Adriano Euripedes , Pereira Rufino Hugo Leonardo , Moreira Franciely Pereira
Published: December 2024

Due to problems such as lack of interconnectivity between all 33 locations, between secretariats and several other points in the municipality, as well as difficulties in hiring, support, and speed of services provided by the telecommunications company, as well as security risks and adjustments to LGPD 13.709 /2018 and finally better management of IT resources, one of which was server virtualization, it was necessary to implement Cloud Phone telephony systems, Internet Mpls with Virtual Private Network at all points and server virtualization within the scope of the City Hall of Ibiá, Minas Gerais, represented a major transformation of the municipal IT infrastructure. The shift from a decentralized environment to an integrated structure has revolutionized operational efficiency, optimizing resources and increasing cybersecurity, as well as platform-as-a-service usage. The interconnectivity between all municipal public management locations facilitated communication and collaboration between different sectors and departments, enabling remote work and adaptation to new needs as they arise.
ANALYSIS OF THE INTERSECTION BETWEEN FASHION AND MUSIC IN TAYLOR SWIFT'S TEN ERA: A CORRELATION STUDY
Authors: Casagrande Dal Bello Leticia , De Lima Dassoler Maria Julia , Vieira Alves Guilherme
Published: December 2024

Fashion and music have always had a close relationship, as both are forms of expression, with fashion being used as a form of identification for each group according to their musical style. In the 2000s, with the growth of the media and the internet, the relationship between fashion and music intensified even further, the way each artist dressed became more visible, which led to each rhythm adopting its own unique style. Taylor Swift, a singer who emerged in 2006, broke records with her first album, one of which was staying on the Billboard 200 for longer than any other album in the 2000s. Although she began her career in country, throughout the Over the years, Taylor has moved through different musical genres, such as Country-pop, Pop, Electronic, Rap, Folk and Alternative, demonstrating remarkable versatility in his compositions. Due to this versatility, the singer needed to make the meaning of each era increasingly explicit, seeking a relationship with fashion and what clothing would represent at each stage of her career. Therefore, the general objective of the research was to descriptively investigate the relationship between music and fashion in the career of singer Taylor Swift, in order to understand how the artist's changes in style affected her career and her relationship with the public. To achieve these objectives, the methodology of this study is basic research, a qualitative approach, bibliographical research, as well as a case study of Taylor Swift.
Keywords: fashion; music; Taylor Swift.
PREDICTING INSOLVENCY IN BRAZILIAN COMPANIES USING MACHINE LEARNING:
Authors: Aparecida Cunha Michele , Sérgio Torres Penedo Antonio , Luiz de Moraes Barboza Flávio
Published: December 2024

Corporate insolvency prediction serves as a valuable strategic parameter to proactively identify financial and managerial risks. Recent approaches to bankruptcy prediction have predominantly leveraged machine learning algorithms, demonstrating superior predictive accuracy compared to conventional methods. This study highlights the effectiveness of the Random Forest methodology in insolvency assessments. Consequently, an exploratory analysis was conducted to evaluate the feasibility of employing a bankruptcy prediction model within the scope of publicly traded Brazilian companies using machine learning techniques. The sample is made up of companies with delisting status on the B3 stock exchange due to insolvency, between 2005 and 2018, a period in line with the enactment of Brazilian legislation on the subject. Evaluation of the model in Brazilian companies revealed an accuracy of 98% in predicting bankruptcies, highlighting the effectiveness of the Random Forest model as a valuable resource for investors, corporate decision makers and interested parties. This research contributes significantly to the discourse surrounding the adoption of machine learning tools in the field of bankruptcy prediction in the Brazilian business scenario.
IMPLEMENTATION OF VIRTUAL REALITY AS A DEMONSTRATION TOOL IN A BALLISTIC LABORATORY
Authors: Rezende Isabela da Costa , Soares da Silva Lucas , Angelo Cestaro Diego , Aparecido Celestino Lopes William
Published: December 2024

Industry 4.0 is revolutionizing automation and services, highlighting virtual reality (VR) as a crucial pillar for new user experiences. This study, carried out in a ballistic protection equipment company, involves commitments in traveling customers to understand the ballistic laboratory and its validation methodologies according to standards. The implementation of VR aims to improve material approval times by providing an improved view of product validation methods and equipment. The objective of this article is to evaluate the use of a VR application to demonstrate testing methodologies in an armor company's ballistic laboratory. Developed based on DSR (Design Science Research), the project ranges from problem identification to application approval, which achieved 90% flexibility among the company's experts when integrating the use of the application into validation processes. The application of this project facilitated the validation of new projects, streamlined technical meetings and process presentations, as validated by experts in the ballistics field.
POTENTIALITY OF HIGH-SPEED LASER CLADDING (HSLC) PROCESS FOR METAL DEPOSITION IN THE BRAZILIAN SCENARIO
Authors: Silva Pinto João Henrique , Trevizan Pacheco Jeferson , Ramlow Heloisa , Gasser Andres , Gonzaga Trabasso Luís , Werner Teichmann Erwin
Published: December 2024

This study explores the potential of High-Speed Laser Cladding (HSLC) within the Brazilian context. Given the nascent stage of HSLC technology in Brazil, preliminary experiments were conducted to assess its technical feasibility. AISI 316L tubes served as substrates for AISI 316L steel coatings, with the thickness of the deposited layers thoroughly analyzed. Results showed consistently continuous and adherent coatings without delamination. The findings suggest that HSLC is well-suited for high-quality, efficient applications in Brazil's oil, mining, and automotive industries, highlighting its potential to meet the demands of these sectors for innovation and precision.
Inducción de microorganismos eficaces (EM) en la masa fermentativa del cacao (Theobroma cacao L.) y su incidencia las características físico química y antioxidante.
Authors: Intriago Flor Frank Guillermo , Cedeño Loor Jossenka , Parraga Muñoz Carlos , Alvarado Vásquez Kerly , Vásquez Cortez Luis , Revilla Escobar Karol , Aldas Morejon Jhonnatan
Published: December 2024

Esta investigación evaluó el impacto de los microorganismos efectivos (ME) en la fermentación del cacao y su influencia en sus características físicas, químicas y antioxidantes. Se utilizó un Diseño Estadístico Completamente Aleatorizado con dos factores: tipo de fermentación (saco de yute o cajas de madera) y concentración de ME (1 %, 3 % y 5 %), durante seis intervalos de fermentación (0, 24, 48, 72, 94 y 120 h). Los parámetros analizados incluyeron temperatura, pH, °Brix y peso del grano. Los resultados mostraron un impacto significativo de la aplicación de ME. El mayor contenido de fenoles (24.17 g GAE/100g) se observó con 3 % de ME en cajas. La capacidad antioxidante fue mayor con 5% de ME en sacos de yute (método ABTS) y 3 % de ME en sacos (método DPPH, 184.01 µmol Equivalente Trolox/g). La fermentación óptima se logró con 5% de ME en cajas y 1 % de ME en sacos, obteniendo valores de calidad del 79 % y 85 %, respectivamente. El análisis de color instrumental no mostró diferencias significativas. La inclusión de ME en la fermentación del cacao afectó positivamente la calidad del grano, mejorando sus propiedades físicas, químicas y antioxidantes, aunque los resultados variaron según la concentración de ME y el tipo de fermentación.
Public Order and the Technological Revolution: Implications for Police and Citizen Safety
Authors: Cucoreanu Cristian
Published: December 2024

The scientific article examines the impact of the technological revolution on public order and how it influences policing. It aimed to emphasize the importance of adapting security strategies to the new digital realities, defining public order in the current technological context. It also discussed the advantages and limitations of monitoring and surveillance systems, as well as the use of mobile technologies that improve the efficiency of police interventions. The article also addresses the ethical and legal dilemmas posed by digital surveillance, highlighting the need to strike a balance between security and the right to privacy. It concludes that police regulations and practices need to be adapted to meet the challenges posed by emerging technologies, thus ensuring the protection of citizens' rights in this complex era.
21st Century Criminology: Bridging Theory and Practice
Authors: Cazacu Florin
Published: December 2024

The article discusses the evolution of criminology as a scientific discipline, emphasizing the importance of integrating theory with practice in the field of criminal justice. The aim of this scientific endeavour was to analyse contemporary challenges of crime, the impact of modern technologies on criminal investigations, and the role of academic institutions in training specialists. The article examines the unique context of the Republic of Moldova, emphasizing both the advancements and challenges within the criminal justice system.
Attempts to Expand the Competencies of External Public Auditors into the Area of Consultancy — Case of the Romanian Court of Accounts
Authors: Bostan Ionel
Published: December 2024

This paper examines the potential effects of legislative proposals aimed at amending Law No. 94/1992 on the organization and functioning of the Romanian Court of Accounts. Primarily, it is observed that if these initiatives were adopted, they would allow public entities to request information, methodological clarifications, or detailed answers to various questions from the regional Chambers of Accounts. The responses would need to be provided in writing, in the form of an opinion, within 30 days. If the applicant finds the opinion unsatisfactory, they would have the right to challenge it, with justification, within 10 days of receiving the document. Subsequently, a specialized court would resolve the challenge within 10 days of its registration, either upholding or annulling the opinion, in whole or in part. However, the Legislative Council, in its advisory opinion, pointed out that assigning the Court of Accounts the obligation to provide periodic consultancy to interested parties contravenes its constitutional role. Such a mandate would diminish the institution's primary function—control—thereby questioning the balance and efficiency of its activities. Other opinions, discussed in the paper, also highlight delays in legislatively transitioning the Romanian Supreme Audit Institution from financial control to specialized consultancy. The structure of this study includes: (1) Introductory considerations on the creation and functioning of the Romanian Court of Accounts, (2) An analysis of parliamentary efforts to orient the Court's activity toward providing specialized consultancy to public entities (2.1 - An initial initiative focusing on guidance/prevention and discouraging auditor misconduct; 2.2 - Attempts to introduce provisions in Law No. 94/1992 establishing consultancy as a task for auditors), and (3) Conclusion.
O NASCIMENTO DO EU A PARTIR DA RELAÇÃO ENTRE MUNDO E O OUTRO: uma análise arenditiana
Authors: Lima Adenaide Amorim
Published: December 2024

Este texto tem como objetivo compreender a concepção do Eu em Hannah Arendt. Trata-se de uma pesquisa bibliográfica que, a partir de suas principais obras – A condição humana e A vida do espírito - explora como a percepção sensorial e a linguagem desempenham papéis cruciais na constituição do sujeito. Arendt inverte a lógica tradicional que considera o outro como secundário, sustentando que a realização plena do sujeito depende do reconhecimento mútuo. Além dos cinco sentidos, ela propõe a existência de um “sexto sentido”, relacionada à capacidade de articular experiências e significados por meio da linguagem. Essa capacidade não só constrói um mundo compartilhado, mas também molda a percepção e a consciência, permitindo uma reflexão profunda sobre si mesmo, o outro e o mundo. A política é entendida como o espaço onde a relação entre os sujeitos se concretiza por meio da ação e do discurso. A vida privada, em contrapartida, é percebida como uma forma de morte simbólica, já que o Eu não pode existir plenamente sem ser visto e reconhecido pelos outros. Assim, a existência humana se realiza no espaço público, onde a pluralidade de perspectivas configura um mundo comum, enfatizando que a linguagem e a intersubjetividade são essenciais para a construção da realidade e da identidade onde a autenticidade do Eu é constituída na interação com o mundo e o outro.
A narratividade formativa Ética em Paul Ricouer
Authors: Brito Herasmo Braga de Oliveira
Published: December 2024

Neste estudo partimos da reflexão em torno da narrativa e das ideias formuladas por Ricoeur, relacionando com as questões da interpretação, do tempo e dos elementos éticos e estéticos, para confrontarmos a convergência nas narrativas diante da composição de uma poética no âmbito do pensamento de Paul Ricouer. A análise terá por base os três tomos de Tempo e Narrativa (2010a, 2010b, 2010c,), O si-mesmo como outro (2014), e Teoria de Interpretação (2019). Em Ricoeur o encontro nas narrativas da ética, estética, hermenêutica de si, reconhecimento de si através do outro, o experenciar em profundidade, o que as narrativas nos apresentam, a qualidade da prosa literária, a intuição estetizada, porquanto todas vão na direção de reconfigurar o sujeito, para torná-lo na prática um ser de ação ética com as pessoas, com o mundo, pela ampliação dos seus horizontes hermenêuticos/interpretativos acerca das coisas.
Strengths and Limitations of an Online Qualitative Survey in Times of Social Crisis: Example of the COVID-19 Pandemic
Authors: Bielska Beata , Kalinowska Katarzyna , Męcfal Sylwia , Surmiak Adrianna
Published: December 2024

The aim of the article is to argue that an online qualitative survey (OQS) is a useful research technique that is feasible to apply during a social crisis such as the COVID-19 pandemic. An OQS has an unclear status in the spectrum of research techniques, as it combines features of quantitative and qualitative research, and there is little recognition in the literature of its advantages and disadvantages in the context of other research techniques used during a social crisis. We describe our research experiences of using this technique and the experiences of our survey participants. We also compare the strengths and limitations of using an OQS during the COVID-19 pandemic against other techniques used at the time.
Pharmacokinetics of lincomycin following intravenous administration in febrile goats
Authors: Sharma Meemansha , Dumka Vinod Kumar
Published: December 2024

Disposition of antimicrobials is known to be altered during disease conditions and fever is one of the common manifestations of bacterial infections in animals. The disposition of lincomycin (10 mg/kg, IV) during Echerichia coli endotoxin-induced fever in goats followed two compartment open model and drug was detected in plasma up to 8 h. The high AUC (39.5±6.21 mg.h/mL) indicated good antibacterial activity of lincomycin in goats. The volume of distribution and total body clearance were 3.35±0.45 L/kg and 0.28±0.03 L/h/kg, respectively. The long elimination half life 9.93± 2.83 h indicated persistence of drug for longer period in body. Lincomycin, is suggested to be repeated at 24 h interval for organisms sensitive to lincomycin having MIC up to 0.6 µg/mL for the treatment of bacterial infections manifested with fever in goats.
Physiochemical and nutritional attributes of raw and soaked seeds of chickpea (Cicer arietinum L.) genotypes
Authors: Kaur* Satvir , Kaur Sarbjit , Gupta Anil K , Kaur Jagmeet
Published: December 2024

The present investigation aims to analyze nutrient profile, antinutritional traits and physiochemical characteristics in raw (dry seeds) and water soaked seeds of eighteen chickpea genotypes comprising 16 cold stress tolerant and 2 susceptible. Raw seeds of tolerant genotypes were found to have higher total sugars and protein content and lower amount of trypsin inhibitors. Higher content of raffinose family oligosaccharides in tolerant genotypes is an additional characteristic for their tolerant behaviour and it does not interfere with the digestion as with soaking these oligosaccharides are reduced by 87%. The enhanced mineral content with soaking in tolerant chickpea genotypes might be attributed to the better physiochemical characteristics in terms of higher hydration capacity and swelling index which leads to greater permeable and softer cotyledons that might help in leaching out of mineral ligands. The higher nutritional value along with better physiochemical characteristics observed in tolerant genotypes render them useful at consumer level as well as from breeding point of view.
três inquietações
Authors: Raffaele Rafaela
Published: December 2024

O presente artigo trata de demonstrar, a partir do projeto para a sede do Bankinter, elaborado por Rafael Moneo entre 1972-1977, como as inquietações em torno da matéria, da construção e da lógica matemática se manifestam de modo recorrente naquele momento de sua trajetória. Como metodologia, o estudo dedutivo levou a uma revisão bibliográfica dos textos que demonstram a relevância destes três aspectos teóricos, presentes especialmente em periódicos europeus e norte-americanos das décadas de setenta, oitenta e noventa. Além disso, construiu-se uma análise projetiva tendo como instrumento analítico o redesenho. Ao longo da análise da obra de Rafael Moneo, identificou-se que boa parte de sua produção se apresentava de modo fragmentado – em entrevistas, registros de aulas e memoriais de projeto – dificultando uma compreensão linear de suas inquietações. Da mesma forma se observa sua arquitetura, a partir de múltiplos fragmentos. Diante desta complexidade inicial em compreendê-la como um todo comum, caberia, ao menos, a produção um entendimento que apresenta origem nas três inquietações e se exemplifica neste recorte projetivo.
WILL THE HEART “GO LAST” IN THE FUTURE? ALIENATING SPACES IN MARGARET ATWOOD’S DYSTOPIAN FICTION
Authors: Ćuk Maja , Parezanović Tijana V.
Published: December 2024

The aim of this paper is to analyse how the disturbing social forces affect individuals in Margaret Atwood’s dystopian novel The Heart Goes Last, by relying on Michel Foucault’s system of ideas on imprisonment in Discipline and Punish and Erich Fromm’s views on disintegration of love and faith in Western society in The Art of Loving. At the beginning of the book, it seems that the Positron Project, a futuristic prison, will offer an escape from post-apocalyptic misery to Stan and Charmaine, a young couple, hit by an economic collapse. However, the suburban paradise, at first glance, has gradually been exposed as a bleak and threatening place where people are kept in cramped conditions under constant monitoring and registration of data. As our analysis will reveal, the town of Consilience is the morbid urban realm where control is enforced through various mechanisms used to create “productive” and “subjected” bodies. In such a system, where the management has enticed the participants to take part in the project by offering material comforts, love has no (economic) value. The circumstances in the alienating location in the mentioned novel might be interpreted as a cautionary tale about relations of power in the current society and the world in the near future. In a metaphorical way, the author of The Heart Goes Last alerts to the problems by which mankind as a whole might be afflicted - the potential for abuses of power, treating people as commodities and the disintegration of real values.
Antioxidant Properties of Various Yacon Leaf Water Extracts and Physicochemical Profile of Decoction During Refrigerated Storage
Authors: Wicaksana Firman , Hartanti Dwi , Hamad Alwani
Published: December 2024

Background: Yacon (Smallanthus sonchifolius (Poepp.) H.Rob.) leaves show promising antioxidant properties, and have traditionally been  used for diabetes management in Baturraden, Banyumas, Central Java, Indonesia. This study evaluated the effects of traditional extraction methods and crude drug-to-solvent ratios on the content and activity of antioxidants and physicochemical properties of yacon leaf water extracts during storage. Methods: Crude drugs were extracted by infusion, short-time decoction, and longer-time decoction at ratios of 1:10, 1:20, and 1:100 (w/v). Antioxidant content was analyzed using standard total flavonoid content (TFC) and total phenolic content (TPC). The antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity and ferric-reducing antioxidant power (FRAP) assays. Yacon leaf water extracts at a ratio of 1:20 (w/v) were stored in tightly closed bottles at 4±2°C for 26 days. The organoleptic characteristics, color, pH, TFC, TPC, and DPPH scavenging activity were evaluated on days 0,1, 3, 6, 12, 18, and 26. Results: The different methods and crude drug-to-water ratios generated different antioxidant activities and contents of the yacon extracts. Yacon leaf decoction for 15 min in a ratio of 1:20 (w/v) produced extract with the best scavenging activity (450.27±5.48 mM Trolox equivalent (TE)/100 g dry weight (DW)), TFC (6.43±0.18 mg Quercetin equivalent (QE)/g DW), and TPC (3.91±0.04 mg gallic acid equivalent (GAE)/g DW). The yacon leaf decoction started to undergo aroma and PH changes on days 3 and 6, respectively. On day 12, the TFC, TPC, and DPPH SA of yacon leaf decoction remained 93.93±3.70, 96.52±1.81, and 89.99±0.91% of the freshly prepared extract, respectively. Conclusion: Our results suggest that extraction using the decoction method for 15 min at a water-to-crude drug ratio of 1:20 (w/v) generated an extract with the best antioxidant profile, which chemically started to change on day 12 during refrigerated storage.
Review: Indole Alkaloids and Antimalarial Activity in the Tabernaemontana Species
Authors: Hutami Anisa Tri , Ekasari Wiwied , Rudyanto Marcellino
Published: December 2024

Background: Malaria, caused by Plasmodium parasites, is a highly prevalent and lethal illness that shows persistent ability to develop resistance. Antiplasmodial compounds that are indole-based prevent hemozoin formation, exhibiting efficacy against chloroquine-resistant Plasmodium strains. Tabernaemontana is a member of the genus comprised  to the Apocynaceae family and has long been known for its efficacy in traditional and herbal tribal medicine. Apocynaceae can be recognized by the existence of indole alkaloids, and Tabernaemontana spp. is widely identifiable for its ability to synthetize a wide variety of indole alkaloids. Objective: This literature review seeks to provide a comprehensive summary of indole alkaloid compounds from Tabernaemontana spp. and the effectiveness of Tabernaemontana spp. as antimalarials. Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocols were followed to explore the PubMed, Sage Journal, ScienceDirect, and Wiley Library databases. Results: 23 publications on the antimalarial activity and indole alkaloids of several species of the genus Tabernaemontana were discovered. Conclusion: Various species of Tabernaemontana contain indole alkaloids, and extracts of the plant or parts of the plant and isolates have weak to strong antimalarial activity.
Anti-Ulcer and Antioxidant Activities of Chrysophyllum albidum G. Don. Seeds Cotyledons
Authors: Owolabi Tunde , Okubor Philippine
Published: December 2024

Background: Gastric ulcers are prevalent gastrointestinal disorders with significant global implications owing to their prevalence and potential complications. Side effects associated with synthetic drugs have led to the search for alternative treatments. Chrysophyllum albidum, a plant traditionally used to manage various diseases, has been investigated for its potential to alleviate ulcerative conditions. Methods: This study assessed the efficacy of extracts from C. albidum seed cotyledons in mitigating ethanol- and diclofenac-induced ulcers in rats. Phytochemical screening was performed using standard methods and antioxidant activities were evaluated using DPPH scavenging and ABTS+-reducing assays. Results: For ethanol-induced gastric ulcers, extracts at doses of 100, 200, and 400 mg/kg produced lesion indices of 7.04 ± 0.44, 5.18 ± 0.38, and 2.53 ± 0.46 mm, respectively, compared to omeprazole's 0.9 ± 1.09 mm. The highest dose showed 87.93% inhibition, which was comparable to that of omeprazole (93.63% inhibition). A similar trend was observed for diclofenac-induced ulcers. Phytochemical analysis revealed the presence of active compounds, such as steroids, flavonoids, polysaccharides, alkaloids, and cardiac glycosides. Antioxidant activity results indicated significant free radical scavenging properties, with an IC50 value of 49.24 µg/mL for DPPH and 15.1 µg/mL for ABTS+ at a dose of 400 mg/kg. These findings demonstrate the notable dose-dependent anti-gastritis and anti-ulcer effects of the extract. Conclusion: This study highlights the potential of C. albidum seed cotyledons as a valuable candidate for gastroprotective drug development and supports their traditional use in treating and preventing gastritis and gastric ulcers.