bluuebunny/crossref_metadata_2025 huggingface dataset:
Correlation of Womac Index and Cytokine Values in Patients with OA Knee
Authors: Miloševic Jelena , Grbović Vesna , Jurišić-Škevin Aleksandra
Published: October 2022

Osteoarthritis (OA) of the knee (gonarthrosis) is a degenerative rheumatic disease, which is the most common rheumatic disease. Numerous factors, such as mechanical, enzymatic, and biological, are responsible for the development of this complex, multifactorial disease. The connection between inflammation and the development of knee OA is being investigated more and more. Cytokines are thought to be one of the main causes of disturbances in normal cartilage metabolism.

This study, designed as a prospective cohort study included 60 patients with knee OA. The examinees were recruited from total population of patients with knee OA, hospitalized or treated as outpatients at Department of Physical Medicine and Rehabilitation, University Clinical Centre Kragujevac. After the consent was obtained, anamnestic data were collected, blood samples were taken and functional testing was done together with anthropometric measurements. The values of the following cytokines were determined from a blood sample: IL-6, TNF-α, IL-10, IL-17. The average age of patients was 69.10±9.06 years, most of whom were females (78,3%). Both IL-6 and TNF-α correlated positively with WOMAC scores. WOMAC index subscales showed different association with cytokines. In our studies the level of cytocines in the serum of pacients with OA knee is show not correlation with radiographic image.

The present study demonstrated than the concentrations of proinflammatory cytokines (TNF-α IL-6) can be correlated with WOMAC scores of knee OA patients. The results indicate that concentrations of TNF-α and IL-6 may affect knee joint function in patients with knee OA.
Gender inequality: The economic dimension
Authors: STRIZHAKOVA Ekaterina N. , STRIZHAKOV Dmitrii V.
Published: October 2022

Subject. This article discusses the issues of economic and political discrimination. Objectives. The article aims to analyze gender inequality in the countries of the world. Methods. For the study, we used general scientific research methods. Results. The article determines the loss of world GDP due to the unresolved problem of gender parity, as well as the human development index for women and men in Russia in the aspect of achieving gender equality. Conclusions. Indicators of gender inequality are calculated with a significant delay. The problem of closing the significant wage gap between men and women has not yet been solved. A shift is needed to create jobs where the best results can only be achieved through the combined efforts of men and women.
Una función pública estratégica: el teletrabajo en la Administración Autonómica. Análisis jurídico-administrativo
Authors: Rastrollo Suárez Juan José
Published: October 2022

La articulación de un régimen jurídico del teletrabajo en el sector público se ha convertido en un imperativo necesario en las administraciones públicas para hacer frente a situaciones de crisis. Sin embargo, antes de 2020, no existía regulación básica sobre la materia en España. No obstante, algunas comunidades autónomas contaban con experiencias y regulación sobre la cuestión desde principios de la segunda década del siglo XX. A lo largo del presente trabajo, examinamos y analizamos desde una perspectiva jurídico-administrativa la legislación en materia de teletrabajo vigente en la legislación autonómica, centrándonos en los que consideramos aspectos clave para su desarrollo en el marco de la función pública.
La asistencia y coordinación sociosanitaria en el medio rural en Castilla y León. Aspectos a mejorar tras la pandemia
Authors: González Iglesias Miguel Ángel
Published: October 2022

Nuestra sociedad envejece, lo que conlleva una mayor presencia de enfermedades crónicas, dependencia y los necesarios cuidados personales de quienes las padecen. Para estos pacientes, el logro de una asistencia sociosanitaria integral, sobre todo en el medio rural, requiere, entre otras cuestiones, de una adecuada coordinación y planificación de los servicios sanitarios y sociales, lo cual se ha puesto de manifiesto, más aún si cabe, con la irrupción de la pandemia del COVID.
Los contornos de la autoprovisión administrativa en la gestión de los servicios públicos
Authors: Noguera de la Muela Belén
Published: October 2022

A caballo entre la potestad de autoorganización que ostentan las Administraciones Públicas y el principio de concurrencia en la adjudicación de los contratos, se sitúan los encargos a medios propios personificados, denominados también, fórmulas de cooperación vertical que, junto con la cooperación horizontal (convenios interadministrativos) aparecen excepcionados de la aplicación de las directivas de contratación pública de 2014. Estas técnicas de autoprovisión administrativa (en las que no se incluye la transferencia de competencias) son objeto de estudio en este trabajo a la vista de la regulación contenida en la LCSP de 2017 y en la LRJSP, partiendo de lo previsto en la normativa comunitaria de contratación pública y la reciente y clave jurisprudencia del Tribunal de Justicia de la Unión Europea (ISE-Colonia, Remondis 2, Porin Linjat, IREN Spa), con el propósito de fijar sus contornos. Mereciendo especial atención la mecánica de estas fórmulas en el ámbito local, al entroncar, asimismo, con el debate en torno a la forma de gestión más idónea de los servicios públicos locales y a su nivel óptimo de prestación. Resultando también de especial atención el recurso a la «gestión directa asociativa mediante contratación in house» analizada en la relevante Sentencia de la Sala de lo Contencioso Administrativo del Tribunal Superior de Justicia de Cataluña núm. 36661/2020, de 21 de septiembre (caso Ayuntamiento de Collbató-CONGIAC-GIACSA).
Las retribuciones de las Administraciones públicas españolas. Un estudio de su equidad interna
Authors: Arenilla Sáez Manuel , Llorente Márquez Jesús , Redondo Lebrero Juan Carlos
Published: October 2022

Este artículo aborda el análisis de las retribuciones de más de veinte mil puestos en el estrato superior de las Administraciones públicas españolas desde la perspectiva de su equidad interna, su estructura salarial y su vinculación con la carrera vertical. Para ello se han estudiado la Administración central de cinco comunidades autónomas, de cinco Administraciones locales y de la Administración General del Estado (AGE).
Entre los principales resultados alcanzados en la investigación hay que destacar la existencia de significativas diferencias retributivas en las Administraciones implantadas en la Comunidad Autónoma Madrid; existe un solapamiento retributivo en los niveles bajos de los puestos superiores que puede generar desmotivación en los funcionarios públicos; los abanicos salariales de las Administraciones estudiadas son relativamente estrechos, destacando las de Bilbao y el País Vasco; la equidad interna es débil al no existir una buena correspondencia entre la responsabilidad y las retribuciones asignadas en los puestos superiores; la implantación de una futura carrera horizontal supondría un incremento en el gasto de personal de muchas Administraciones públicas; y la carrera de la función pública superior en España es relativamente corta.
PENERAPAN PRAKTIK HAND HYGIENE YANG BENAR DI SDN 5 TOBOH PALABAH KOTA PARIAMAN
Authors: Silvia Elwitri , Suganda Yohana
Published: October 2022

Hand hygiene merupakan salah satu elemen penting dalam mencapai salah satu target SDG’s tahun 2030. Hand hygiene mencakup mencuci tangan pakai sabun (CTPS) dan penggunaan hand sanitizers. Hand hygiene memberikan manfaat kesehatan yang besar dengan biaya yang relatif kecil. Personal hygiene anak-anak dianggap sebagai alat terbaik untuk mencegah penyakit menular yang memengaruhi masa pertumbuhan dan perkembangannya. Pendidikan kesehatan tentang hand hygiene merupakan satu-satunya cara yang hemat biaya agar terwujudnya penerapan hand hygiene yang baik dan benar. SDN 5 Toboh Palabah Kota Pariaman merupakan institusi pendidikan anak yang berada di pinggir jalan yang banyak dilalui oleh kendaraan dan masyarakat sehingga sangat penting diberikan pendidikan kesehatan tentang hand hygiene. Selain itu berdasarkan wawancara dengan para guru menyatakan bahwa belum ada penyuluhan kesehatan tentang cara mencuci tangan dan penerapan hand hygiene dari petugas kesehatan. Kegiatan pendidikan kesehatan ini diikuti oleh siswa kelas 5 dan 6 SDN 5 Toboh Palabah Kota Pariaman yang berjumlah sebanyak 21 orang. Kegiatan dibagi menjadi dua sesi. Sesi pertama adalah penyampaian materi dan sesi kedua adalah praktik langkah-langkah cuci tangan pakai sabun dan menggunakan hand sanitizers. Kegiatan berlangsung lancar dan mendapatkan respon positif baik pada sesi pertama maupun pada sesi kedua. Seluruh siswa dapat mempraktekkan langkah-langkah cuci tangan dan memahami penerapan hand hygiene dengan benar. Dengan adanya pendidikan kesehatan ini kami berharap warga sekolah khususnya siswa-siswa SDN 5 Toboh Palabah Kota Pariaman dapat menerapkan dan mengoptimalkan penggunaan fasilitas sekolah agar penerapan hand hygiene dapat dilakukan degan baik dan benar.
Fratura peniana: uma revisão narrativa
Authors: Junior Carlos Lopes do Prado , Carneiro David Ricardo Lima
Published: October 2022

Objetivo: Revisar estudos que abordem o diagnóstico e a terapêutica da fratura peniana e descrever de forma objetiva seus principais desdobramentos, incluindo as mais frequentes complicações diante de uma tardia ou não intervenção cirúrgica. Revisão bibliográfica: A fratura peniana é definida como a ruptura da túnica albugínea do corpo cavernoso e tem como principal mecanismo de trauma o intercurso sexual traumático, usualmente devido à compressão do pênis ereto sobre o períneo ou a sínfise púbica da mulher. No entanto, existem outros mecanismos de trauma variados. O diagnóstico da fratura peniana, em sua grande maioria, é prioritariamente clínico, através da anamnese e exame físico adequado. O tratamento atual de escolha é a abordagem cirúrgica imediata. A idade avançada e a extensão da ruptura na túnica albugínea podem estar associadas ao desenvolvimento de disfunção erétil, assim como, o intervalo entre o trauma e o tratamento cirúrgico também se relacionam com os resultados, ou seja, quanto mais rápido se inicia a abordagem cirúrgica, menores são as complicações pós-operatórias como disfunção erétil e curvatura peniana. Considerações finais: A abordagem precoce, com a identificação e pronta intervenção a lesão, associa-se com menores chances de evolução para disfunção erétil e outras complicações associadas a fratura peniana.
Correlation between Quality of Life and Burden in Caregivers of Advanced Stage Cancer Patients on Best Supportive Care
Authors: Manivannan Manavalan , Karunanithi Gunaseelan , Lakshminarayanan Subitha
Published: October 2022

Objectives:

Patients with advanced cancer with incurable diseases are generally cared for by their families in India. There is a lack of data on the perceived caregiver burden, quality of life (QOL) of patients and caregivers in India, especially among cancer patients not on any oncologic management.

Material and Methods:

We conducted a cross-sectional study among 220 patients of advanced cancer on best supportive care and their respective 220 family caregivers. Our primary objective was to identify a correlation between caregiver burden and QOL. After taking informed consent from both patients and caregivers, we assessed the QOL of the patient using the European Organization for the Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 15 Palliative Care (QLQ C15PAL) questionnaire from the patient, assessing the Caregiver Burden using Zarit Burden Interview, assessing the QOL of the caregiver using the WHO QOL BREF Questionnaire, in a single session during their routine follow-up in the Palliative Care Clinic of our institution.

Results:

We noticed a statistically significant negative (Spearman) correlation between the Caregiver Burden as assessed by Zarit Burden Interview (ZBI) and the psychological (r = −0.302, P < 0.01), social (r= −0.498, P < 0.01) and environmental (r = −0.396, P < 0.01) domains of the WHO QOL BREF Questionnaire. Caregiving Burden as assessed ZBI total score was noted to have a statistically significant negative correlation with physical functioning (r = −0.37, P < 0.01), emotional functioning (r = −0.435, P < 0.01) and global QOL scores (r = −0.499, P < 0.01) assessed from the patient using the EORTC QLQ C15 PAL questionnaire. It also had a statistically significant small positive correlation with EORTC QLQ C15 PAL symptom scores, such as dyspnoea, insomnia, constipation, nausea, fatigue and pain. The median caregiver burden score was 39, showing higher burden as compared to previous studies. Caregivers who were spouses of the patient, illiterate, homemakers, with low-income families reported higher burden.

Conclusion:

A high perceived caregiving burden is associated with impaired QOL in family caregivers of advanced cancer patients on best supportive care. Multiple patient related factors and demographic factors tend to affect burden of the caregiver.
Unilateral Transudative Pleural Effusion due to rare Cause – A Case Report
Authors: Bhaskar K. , Devanandan K. , Jain Jitendar Kala , Krishna Tella , Gongati P.
Published: October 2022

Transudative pleural effusions are characterized by low protein and lactate dehydrogenase according to Light’s criteria. Common causes are congestive cardiac failure, nephrotic syndrome, liver cirrhosis, and protein-losing enteropathy. Constrictive pericarditis is a rare cause of transudative pleural effusion. It can cause bilateral or unilateral recurrent effusions and chylothorax rarely. Common causes of constrictive pericarditis include infections such as viruses and tuberculosis, radiation, and cardiac surgery. We present a treated case of pulmonary tuberculosis presenting with massive, left-sided, and transudative pleural effusion due to constrictive pericarditis diagnosed by computed tomography scan and 2D echo with classical findings. Incidental findings were internal jugular vein thrombus and right lower lobar pulmonary embolus. This case highlights the atypical presentation of constrictive pericarditis as unilateral pleural effusion. A proper history with a high index of suspicion is essential in the workup of constrictive pericarditis which can be cured by pericardiectomy.
Gender Specific Coronary Artery Diameters in CT Coronary Angiogram: A Comparative Study in Female and Male Population
Authors: Thejasree Bairy , Patnaik Sujata , Maddury Jyotsna
Published: October 2022

Objectives:

Women show significant in-hospital morbidity and mortality with greater extent of symptoms, poorer post-revascularization outcome with increased restenosis and repeat revascularization after angioplasty, than men. Smaller sized coronary arteries in females can be attributable for this differential outcome, which is also similar in case of Indians, compared to Caucasians. Our aim is to assess the gender-specific difference in coronary arteries using noninvasive Multidetector Computed-Tomography Coronary-Angiogram(CT-CAG) and comparing the same with other racial database.

Materials and Methods:

With Ethics committee approval, present retrospective comparative study conducted in 128CT-CAG scans in 18-45years aged 100 women and 89 men with no atherosclerotic burden excluding pathological coronaries and high calcium score>100. Diameter measurements of proximal (≤10mm) segments of right coronary artery(RCA), left main coronary artery(LMCA), left anterior descending(LAD) and circumflex(LCx) arteries were taken, averaged and compared using 2-sample z-test. Considering the obtained mean diameters of total sample as South-Indian dataset which is then compared with Caucasians dataset taken from previous study.

Results:

Women showed smaller coronary artery diameters compared to men in all the arteries, with greater gender-specific age-adjusted difference in LMCA, followed by LAD, RCA and least in LCX. South-Indians showed statistically significant smaller diameters of all the coronary arteries compared to Caucasians.

Conclusion:

Gender-specific difference among the coronary arteries does exist, with females having smaller dimensions; South-Indians also show smaller diameters. This warrants a clinician for gender-specific approaches during the interventions because of technical difficulties.
High-Sensitivity C-Reactive Protein-to-Albumin Ratio in Predicting the Major Adverse Cardiovascular Event in Acute Coronary Syndrome at Presentation
Authors: Mir Sajad Rashid , Lakshmi V. S. Bharathi
Published: October 2022

Objective:

Our study aimed to determine the association between high sensitivity-c reactive protein to albumin ratio (CAR) and in-hospital major adverse cardiovascular event (MACE) in patients with acute coronary syndrome and also to assess whether hs-CAR is a better marker than hsCRP or albumin alone in predicting MACE.

Materials and Methods:

We enrolled 110 cases who were hospitalized and major adverse cardiovascular event was defined as cardiogenic shock, acute heart failure, reinfarction and death. Blood sample for Serum albumin and hs-crp was taken at the time when patients were admitted.

Results:

The incidence of MACE was more in patients with high CAR (≥1.8 group) as compared to those with low CAR (<1.8 group).

Conclusion:

The CAR is an independent predictor of MACE in patients who present with ACS.
Digital Platform Ecosystem Dynamics: The Roles of Product Scope, Innovation, and Collaborative Network Centrality
Authors:   Clemson University, Li He , Zhang Chen ,   University of Memphis, Kettinger William ,   Clemson University
Published: October 2022

This research highlights the circulative nature of digital platform ecosystem dynamics. Investigating these dynamics, we examine the mutual influence between participants’ product scope and product innovation over time and probe the moderating role of co-created collaborative networks. We distinguish between two types of product innovation: new product development and existing product updates. Our longitudinal analysis of the Hadoop software ecosystem indicates that participants covering a broader scope of the platform’s technological layers are less likely to develop new products but more likely to update existing products. In turn, participants with more frequent new product development are more likely to expand their product scope, whereas those with more frequent existing product updates are less likely to pursue scope expansion. Participants’ centrality in the ecosystem’s collaborative network amplifies the bidirectional link between product scope and existing product updates but weakens the link between product scope and new product development. Our findings offer a theoretical and practical understanding of temporal dynamics between participants’ product scope choices and different forms of product innovations in the co-created collaborative network environment.
The Role of Social Cues and Trust in Users’ Private Information Disclosure
Authors:   Tel Aviv University, Zalmanson Lior , Oestreicher-Singer Gal ,   Tel Aviv University, Ecker Yael ,   Johannes Gutenberg University Mainz
Published: October 2022

Across different domains, websites are incorporating social media features, rendering themselves interactive and community-oriented. This study suggests that these “friendly” websites may indirectly encourage users to disclose private information. To investigate this possibility, we carried out online experiments utilizing a YouTube-like video-browsing platform. This platform provides a realistic and controlled environment in which to study users’ behaviors and perceptions during their first encounter with a website. We show that the presence of social cues on a website (e.g., an environment in which users “like” or rate website content) indirectly affects users’ likelihood of disclosing private information to that website (such as full name, address, and birthdate) by enhancing users’ “social perceptions” of the website (i.e., their perceptions that the website is a place where they can socialize with others). We further show that the presence of social cues is more likely to enhance users’ social perceptions when users are primed to perceive the website as trustworthy, as opposed to untrustworthy (through the presentation of trust cues such as data protection disclaimers). Moreover, we rule out users’ privacy concerns as an alternative mechanism influencing the relationship between social cues and information disclosure. We ground our observations in goal systems and trust theories. Our insights may be beneficial both for managers and for policy makers who seek to safeguard users’ privacy.
Soft but Strong: Software-Based Innovation and Product Differentiation in the IT Hardware Industry
Authors:   Chinese University of Hong Kong, Kim Keongtae , Lee Jeongsik “Jay” ,   Drexel University, Gopal Anandasivam ,   Nanyang Technological University
Published: October 2022

It has been argued in recent years that software is a significant value-creating factor within the manufacturing sector, leading to an increased interest in understanding the mechanisms by which firms may benefit from software-based innovation. Empirical work in evaluating these mechanisms, however, remains underdeveloped. In this paper, we examine one such process through which software-based innovation may provide value for information technology hardware firms in the U.S. Specifically, we examine the influence of software patents on the extent to which firms are able to benefit from product differentiation in their product markets. Using data on over 380,000 patent grants for innovations filed by 730 public IT hardware firms over the time period 1996-2015, we find that greater levels of software-based innovation within the firm are associated with higher levels of product differentiation in product markets: increases in the intensity of software patents within the firm’s patent stock, which we refer to as software intensity, are associated with lower total similarity of product offerings, relative to those offered by rivals, as well as fewer effective competitors in the market. Furthermore, using a different dataset consisting of 23,000 new IT hardware product announcements, we show that firms with greater software intensity subsequently launch a higher number of new products. Moreover, these firms are more likely to launch products that are not only differentiated from those of rivals but also distinct from their own product lines. Our research contributes to the emerging literature on software-based innovation by substantiating an important mechanism through which software helps transform industry sectors, specifically through product differentiation.
Cross-Lingual Cybersecurity Analytics in the International Dark Web with Adversarial Deep Representation Learning
Authors:   University of South Florida, Ebrahimi Mohammadreza , Chai Yidong ,   Hefei University of Technology, Samtani Sagar ,   Indiana University, Bloomington, Chen Hsinchun ,   University of Arizona
Published: October 2022

International dark web platforms operating within multiple geopolitical regions and languages host a myriad of hacker assets such as malware, hacking tools, hacking tutorials, and malicious source code. Cybersecurity analytics organizations employ machine learning models trained on human-labeled data to automatically detect these assets and bolster their situational awareness. However, the lack of human-labeled training data is prohibitive when analyzing foreign-language dark web content. In this research note, we adopt the computational design science paradigm to develop a novel IT artifact for cross-lingual hacker asset detection (CLHAD). CLHAD automatically leverages the knowledge learned from English content to detect hacker assets in non-English dark web platforms. CLHAD encompasses a novel Adversarial deep representation learning (ADREL) method, which generates multilingual text representations using generative adversarial networks (GANs). Drawing upon the state of the art in cross-lingual knowledge transfer, ADREL is a novel approach to automatically extract transferable text representations and facilitate the analysis of multilingual content. We evaluate CLHAD on Russian, French, and Italian dark web platforms and demonstrate its practical utility in hacker asset profiling, and conduct a proof-of-concept case study. Our analysis suggests that cybersecurity managers may benefit more from focusing on Russian to identify sophisticated hacking assets. In contrast, financial hacker assets are scattered among several dominant dark web languages. Managerial insights for security managers are discussed at operational and strategic levels.
Ambivalence, Creative Investment, Publishing and Development
Authors: Haaz Ignace
Published: October 2022

The role of an academic editor and publisher is not simple. It is even less so when providing guidance and support for authors from the countries of the majority world becomes a habitual condition of this activity. Editorial commitment in this context becomes ambivalent, as it has to be oriented towards meeting two distinct objectives: ensuring academic quality and providing support to authors. To meet this challenge the publisher hopes to make the most of online tools and networks. If some scholarly work fails to be published, it raises the question whether authors would benefit from mentorship to improve their texts and thereby meet with international academic standards. The publisher cannot entirely compensate for the weakness of the research work, but should seek to mitigate it.
On Evolutionary Biology, the Apostle Paul and Common Good
Authors: Bühlmann Quero Jakob
Published: October 2022

In this article our aim is to present some of the coordinates of the debate around common good. Starting by recognizing the importance of common good for the Christian worldview after the presence of it in St. Paul’s “the manifestation of Spirit is given for the common good”, we will present two ways of interpreting the development of our moral and emotional tendencies that have to do with two different evolutionary approaches. By the end of the article, we hope to have established the argumental advantage of the cooperativist in front of the social Darwinist, opening the possibility for a possible interpretation of evolution as guided towards common good.
Review of: B. Frischherz et al. Teaching Intercultural Business Ethics
Authors: Frischherz Bruno , Millar Gordon
Published: October 2022

This is a book review of: Bruno Frischherz, Liu Baocheng, Li Xiaosong, Anoosha Makka, Gordon Millar, Martin Brasser and Menno Brouwer. Teaching Intercultural Business Ethics. Globethics.net Education Praxis Series, Geneva: Globethics.net, forthcoming 2023.
Synthesis and characterization of new N-Heterocyclic-BF3 adducts and their reactivity vs water
Authors: Romo Adolfo I. B. , Hossain Md Sazzad , Woods Toby J. , Rodriguez-Lopez Joaquin
Published: October 2022

Species derived from N-Heterocycles with BF3 Lewis acids generate adducts that are redox active. Here we report the synthesis and characterization of 5 N-Heterocycle-BF3 adducts: Py-(BF3)2, Q-(BF3)2, Ph-(BF3)2, TMQ-(BF3), and Dipy-(BF3)2. The new adducts were structurally characterized by 1H, 11B, and 19F NMR. As an example, the Q-BF3 adduct is stable in an inert environment but in the presence of oxygen or water, its voltammetric profile decays, suggesting chemical decomposition of the adduct. Furthermore, this decomposition is accompanied by the generation of BF4-. The crystalline structure of the reaction product of TMQ-(BF3) with traces of water was obtained, showing that the BF3 generates BF4- counterion. Based on our observations, we proposed a plausible reaction mechanism for the generation of BF4-.
Epitaxial thin film of high entropy oxide as electrocatalyst for oxygen evolution reaction
Authors: Patel Ranjan Kumar , Jenjeti Ramesh Naidu , Kumar Rajat , Bhattacharya Nandana , Klewe Christoph , Shafer Padraic , Sampath S. , Middey Srimanta
Published: October 2022

High entropy oxides (HEOs), which contain multiple elements in the same crystallographic site, are a promising platform for electrocatalysis in oxygen evolution reaction (OER). However, to date, all OER studies involving HEOs have used it in polycrystalline bulk form. In this study, the OER activity of a set of single crystalline thin films of (La0:2Pr0:2Nd0:2Sm0:2Eu0:2)NiO3, grown on NdGaO3 substrates have been investigated. The OER activity increases with the thickness of the film. X-ray absorption spectroscopy measurements find an increase in Ni d-O p covalency and a decrease in charge transfer energy with the increase in film thickness. These facilitate higher charge transfer between Ni and surface absorbates, resulting in higher OER activity. However, the epitaxial stabilization of thicker film becomes difficult due to the requirement of +3 oxidation state of Ni and the OER activity of a 75 unit cell thick film is found to be the optimal in the present study. This work demonstrates that the thickness of perovskite oxides can be used as a parameter to enhance OER activity.
Reversible Alkaline Hydrogen Evolution and Oxidation Reactions Using Ni–Mo Catalysts Supported on Carbon
Authors: Patil Rituja , Kaur Manjodh , House Stephen , Kavalsky Lance , Hu Keda , Zhong Shirley , Krishnamurthy Dilip , Viswanathan Venkatasubramanian , Yang Judith , Yan Yushan , Lattimer Judith , McKone James
Published: October 2022

Unitized regenerative fuel cells based on hydroxide exchange membranes are attractive for long duration energy storage. This mode of operation depends on the ability to catalyze hydrogen evolution and oxidation reversibly, and ideally using nonprecious catalyst materials. Here we report the synthesis of Ni–Mo catalyst composites supported on oxidized Vulcan carbon (Ni–Mo/oC) and demonstrate their performance for reversible hydrogen evolution and oxidation. For the hydrogen evolution reaction, we observed mass-specific activities exceeding 80 mA/mg at 100 mV overpotential, and additional measurements using hydroxide exchange membrane electrode assemblies yielded full cell voltages that were only ~100 mV larger for Ni–Mo/oC cathodes compared to Pt–Ru/C at current densities exceeding 1 A/cm2. For hydrogen oxidation, Ni–Mo/oC films required <50 mV overpotential to achieve half the maximum anodic current density, but activity was limited by internal mass transfer and oxidative instability. Nonetheless, estimates of the mass-specific exchange current for Ni–Mo/oC from micropolarization measurements showed its hydrogen evolution/oxidation activity is within 1 order of magnitude of commercial Pt/C. Density functional theory calculations helped shed light on the high activity of Ni–Mo composites, where the addition of Mo leads to surface sites with weaker H-binding energies than pure Ni. These calculations further suggest that increasing the Mo content in the subsurface of the catalyst would result in still higher activity, but oxidative instability remains a significant impediment to high performance for hydrogen oxidation.
Bioceramics for medical applications: a computational view
Authors: Dash Ritambhara , Rajak Abhay Kumar , Kumar Ramagiri Praveen , Kommu Parameshwar , Sharma Shruti , Gurjar Mukesh , Bhattacharyya Arnab
Published: October 2022

Bio ceramics have enormous applications in the medical field as being used as implants. The base material in bioceramics is mostly calcium phosphate which comes in the form of hydroxyapatite (HAp) or Beta-tricalcium phosphate (β-TCP). The other materials are silica and alumina. The different blends of these bioceramics as well as bioglass are in use for medical implants. The use of simulation and modeling in determining and analysing the structure and function of these bioceramics is used for developing implants, scaffolds, and prosthetics as well as for analysing complex molecular interactions. The use of different molecular dynamics modeling techniques, Density Functional Theory, Finite Element Modeling, Artificial Neural Networks, etc is done in this regard. The results of these modeling and simulations are used for bone grafting, making scaffolds, making dental implants, healing damaged bones, 3D modeling, stress analysis, As removal, nanoindentation, etc. Some software like GROMACS, MEGACELL, and ANOVA is used for this purpose. Hydroxyapatite (HAp) was prepared from egg shells by various routes using hexane and acetic acid followed by heat treatment. Hap has a wide application in water treatment by removal of metal ions. XRD of the samples showed use of acetic acid followed by high temperature sintering leads to formation crystalline phases of HAp. Strong evidence of CaCO3 in calcite phase was obtained in other samples.
Enantioselective Single and Dual a-C–H Bond Functionalization of Cyclic Amines via Enzymatic Carbene Transfer
Authors: Ren Xinkun , Couture Bo M. , Liu Ningyu , Lall Manjinder S. , Kohrt Jeffrey T. , Fasan Rudi
Published: October 2022

Cyclic amines are ubiquitous structural motifs found in pharmaceuticals and biologically active natural products, making methods for their elaboration via direct C–H functionalization of considerable synthetic value. Herein, we report the development of an iron-based biocatalytic strategy for enantioselective a-C–H functionalization of pyrrolidines via a carbene transfer reaction with diazoacetone. Currently unreported for organometallic catalysts, this transformation can be accomplished in high yields, high catalytic activity and high stereoselectivity (up to 99:1 e.r. and 20,350 TON) using engineered variants of cytochrome P450 CYP119 from Sulfolobus solfataricus. This methodology was further extended to enable enantioselective a-C–H functionalization in the presence of ethyl diazoacetate as carbene donor (up to 89:11 e.r. and 8,920 TON), and the two strategies were combined to achieve a one-pot as well as a tandem dual C–H functionalization of the cyclic amine substrate with enzyme-controlled diastereo- and enantiodivergent selectivity. This biocatalytic approach is amenable to gram-scale synthesis and can be applied to drug scaffolds for late-stage C–H functionalization. This work provides an efficient and tunable method for direct asymmetric a-C–H functionalization of saturated N-heterocycles which should offer new opportunities for the synthesis, discovery, and optimization of bioactive molecules.
Electric fields drive bond homolysis
Authors: Zhang Boyuan , Schaack Cedric , Prindle Claudia , Vo Ethan , Aziz Miriam , Steigerwald Michael , Berkelbach Timothy , Nuckolls Colin , Venkataraman Latha
Published: October 2022

Electric fields have been used to control and direct chemical reactions in biochemistry and enzymatic catalysis, yet directly applying external electric fields to activate reactions in bulk solution and to characterize them ex situ remains a challenge. Here we utilize the scanning tunneling microscope-based break-junction technique to investigate the electric field driven homolytic cleavage of the radical initiator 4-(methylthio)benzoic peroxyanhydride at ambient temperatures in bulk solution, without the use of co-initiators or photochemical activators. Through ex-situ quantification by high performance liquid chromatography and UV-vis analysis as a function of time, we find that the electric field catalyzes the reaction. Importantly, we demonstrate that the reaction rate in a field increases linearly with solvent dielectric constant. Using density functional theory calculations, we show that the applied electric field decreases the dissociation energy of the O-O bond and stabilizes the product relative to the reactant due to their different dipole moments.
GENDER EQUALITY FROM THE PERSPECTIVE OF JURISPRUDENCE
Authors: Selva Rajan Nagulan , Joothymani Vanusya , Althabhawi Nabeel Mahdi
Published: October 2022

Recently, in the 2021 Global Gender Gap report which identifies the gap between women and men across four sub-indices: economic participation and opportunity, educational attainment, health and survival, and political empowerment, Malaysia ranked 112 out of 156 countries. Therefore, recognising the significant role of women, Malaysia is committed in achieving gender equality and promoting the rights of women and girls. This paper deals with the socioeconomic status of Malaysian women. It provides an analysis of the views of jurists regarding gender equality and recent trends of the female labour force participation, the areas where the female labour force is concentrated at present, and gender differentials in many ways, and it makes recommendations to improve women’s status. The Paper focuses on the need to enhance more opportunities for Malaysian women as gender equality is not only a basic human right but is also critical in accelerating progress on sustainable development.
Growth and the Internet: Surfing to Prosperity?
Authors: Altig David , Rupert Peter
Published: October 2022

In the late nineteenth century, the economist Thomas Malthus made a simple prediction of economic theory that would result in the discipline being forthwith known as the dismal science. The pessimistic extrapolation for which Malthus is famed foretold of long economic cycles in which widespread famine must be an inevitable part.
Evaluation of English Texts' Readability in National Examination in Indonesia
Authors: Syafri Mohamad
Published: October 2022

The National Examination is still considered one of the main national-scale tests. As one of the subjects tested, English has used many texts in National Examination. This study evaluates the quality of reading texts' readability in the English National Examination for Junior High School from 2014/2015-2018/2019. 2019/2020 and 2020/2021 are not tested due to their cancellation under the health protocol implemented by the government. The study follows the quantitative descriptive evaluation approach. The SMOG formula is used to measure the texts' readability. From the last five English National Examination tests, 31 texts were tested. There are three aspects evaluated: the number of texts per test, words per text, and readability. The study results showed that there are 87 texts used in total from 2014-2015 to 2018/2019. Among them, only 31 texts exceed 150 words. The average texts quantity is 6,2, and the annual growth is 13,6%. The average number of words per text is 224,1, and the yearly growth is 4,6%. The main aspect, the average score of texts readability is 9,71 or at the level "Easy to Read" suitable to 6th Grader, and the annual growth of texts' readability is 3,9%. The study results show an improvement in quantity and quality, specifically for the readability, of the texts used in the English National Examination.
Selecting English Study Programs in Higher Educations: Students’ Perspectives
Authors: Fitria Tira Nur , Pudjiati Danti , Wulandari Fitri
Published: October 2022

This research was to know the students’ reasons for choosing English study programs in higher education. This research was qualitative. There were 62 participants from the English Education study program in various colleges or universities in Indonesia, 32 students were from Public Higher Education, and the rest of the students were from Private Higher Education. The result showed two internal and external factors underlying the students' choosing English study programs. The internal factors were: 1) learning English is full of challenges, 2) English is the international language in the world, 3) it is an opportunity to get a scholarship abroad, 4) they are interested in learning, even deepening, oral and written English skills, 5) they have the desire to be an English teacher after graduation, 6) career prospects for English graduates are widely open, 7) English is the students’ favorite subject at senior high school, 8) English scores are good on their school report card, and 9) English scores are good and satisfactory in the national exam. Several external factors include: 1) the desire to choose the English major appears from themselves (they are not influenced by their parents/family, friends, and school recommendation or request), 2) the prestigious image of being an English major student in the society, 3) no other major at college that attracts their attention, 4) good accreditation, 5) the good reputation of the study program, 6) the superiority among others, 7) the availability of tuition fee information, and 8) the desire to study at their favorite universities.
Burnout among working mothers: The role of work-life balance and perceived organizational support
Authors: Riyono Bagus , Rezki Gebrina
Published: October 2022

The pandemic of COVID-19 has influenced business in general. In response to the COVID-19 pandemic, most companies or organizations have been implementing work from home (WFH). For working mothers who have children, this WFH policy creates a more stressful situation since they simultaneously have to deal with work and family in the same place. This study investigated the role of work-life balance and perceived organizational support in the level of burnout tendency among working mothers. Two hundred thirty-seven working mothers who work from home participated in this study. Questionnaires were distributed to the working mothers to measure work-life balance, perceived organizational support, and burnout tendency. Multiple linear regression was used to test the hypothesis. The results show work-life balance and perceived organizational support simultaneously predict burnout tendency. However, perceived organization support, especially a concern for employee welfare, contributes more to reducing burnout.  Therefore, human resource management may develop a policy to reduce burnout among women employees by concerning employee welfare in terms of compensation and benefit and creating a conducive working environment
Coping strategies to predict the psychological well-being of college students during the COVID-19 pandemic
Authors: Angelica Karina , Sukamto Monique Elizabeth , Chandra Clara Citra , Andrea Kelvin
Published: October 2022

The COVID-19 pandemic in Indonesia has forced college students to undergo online learning. Various problems that arise due to this pandemic, especially those related to academic achievement, can disrupt the students' psychological well-being. This study investigated coping strategies' role in predicting college students' psychological well-being during the pandemic's first wave. Two hundred eleven students participated online in this quantitative study and completed the shortened version of the Psychological Well-Being Scale and the Brief Cope Inventory. The regression analysis results show that problem-focused coping strategies, such as planning and the use of instrumental support, significantly predict the increase in female students' psychological well-being. In contrast, only active coping positively predicts psychological well-being in male students. Dysfunctional coping strategies, such as behavioral disengagement and denial, significantly predict the decline in female students' psychological well-being. On the other hand, venting showed a significant role in predicting the increased psychological well-being of female students. Emotion-focused coping strategies do not significantly predict psychological well-being in female and male students. Therefore, regarding the psychological well-being of college students during the first wave of the COVID-19 pandemic, coping strategies, especially problem-focused and dysfunctional strategies, contribute differently to female and male students.
Differences in health beliefs and behavior compliance of the patients with chronic renal failure
Authors: Safitri Jehan , Seftiana Miranda , Rusli Rusdi
Published: October 2022

Health belief is about a patient’s belief that vulnerability and treatment efficacy can affect health behavior decisions. This research investigated the difference in behavior compliance of patients with chronic renal failure based on gender and health beliefs' contribution to it. The sample of this research was 30 male and 30 female renal failure patients at Brigjend H. Hasan Basry Hospital. Data was collected by behavior compliance scale and health belief scale. Multivariate analysis was used to analyze the data. The results show a significant relationship between male and female patients' health beliefs and behavior compliance. The health belief of male patients is higher than female patients, while the behavior compliance of female patients is higher than males. It can be concluded that health and gender are factors affecting behavior compliance. Therefore, paramedics may increase patients' health beliefs to enhance behavior compliance, especially among female patients with chronic renal failure.
The Concept of Justice in Islam According to Majid Khadduri
Authors: Sirait Sangkot
Published: October 2022

This paper aims to describe the concept of justice in Islam according to Majid Khadduri, a Muslim scholar in the modern era. In Islamic theology, for example, justice is not only related to aspects of humanity but also divinity. In the secular sciences, justice is widely discussed in terms of substance and procedure. Likewise, in the discourse of Islamic theology, the value in question tends only to divinity, meaning that the measure of good value is God or the texts of the holy book. However, for Majid Khadduri, these values are not only related to humanity but at the same time they must be close to what God wants and religion in general. The synthesis of the two views above seems to be united in the concept of Khadduri. Therefore, the problem in this paper is how the construction of justice according to Majid Khadduri and its implications for the formulation of justice in the context of religious humanity. The results of the study show that human actions are judged fairly if they are based on correct norms and carried out with good procedures. In addition, with the development of social problems in society, such as injustice, it is also important to formulate the concept of justice which truly is a concept that can provide and be useful in solving this sense of injustice. This article will contribute and can be used as an approach in creating the spirit of changing, enlightening in Muslim society.
TINGKAT PENGETAHUAN TENTANG MENOPAUSE DAN KESIAPAN MENGHADAPI MASA MENOPAUSE DI DESA BUMI PRATAMA MANDIRA
Authors: Mazida Elly , Wijaya Christian
Published: October 2022

seorang wanita akan mempunyai harapan hidup normal 25 tahun lagi sejak awal menopause. Keterangan menurut WHO pada tahun 2013 jumlah wanita yang ada di dunia dimana yang sudah mengalami masa menopause diperkirakan mencapai 1,42 miliar jiwa. Menopause adalah proses suatu berhentinya menstruasi secara permanen yang dapat dialami oleh semua wanita dan berakhirnya kemampuan bereproduksi yang disebabkan oleh kurangnya fungsi folikel ovarium. Wanita dikatakan menopause jika mereka tidak mengalami menstruasi selama setahun. Sebelum masa menopause terjadi, umumnya seorang wanita akan melewati terlebih dahulu masa premenopause. Premenopause merupakan suatu kedaan fisiologis pada wanita yang telah mengalami masa penuaan, yang dimana ditandai dengan hormone estrogen yang menurun dari ovarium yang berperan penting  dalam reproduksi dan seksualitas. Tingkat pengetahuan wanita yang lebih tentang menopause membantu wanita untuk dapat menyiapkan diri dalam menghadapi menopause. Tujuan dilakukannya penelitian ini untuk mengetahui gambaran tingkat pengetahuan wanita tentang menopause dan kesiapan menghadapi menopause. Jenis dan desain penelitian yang digunakan adalah metode deskriptif. Populasi dalam penelitian ini yaitu ibu dengan rentan usia 45-55 tahun yang ada di Desa Bumi Pratama Mandira dengan jumlah responden sebanyak 201 orang. Hasil penelitian menunjukkan bahwa karateristik responden  terbanyak usia kurang dari 50 tahun (58,7%), berpendidikan SD (44,8%), berpendidikan SMP (28,4%), berpendidikan SMA (23,4%), dan berpendidikan S1 (3,5%), berpengetahuan cukup (48%), berpengetahuan baik (52%), memiliki tingkat kesiapan menghadapi menopause (56,3%) dan belum siap menghadapi menopause (43,7%).