bluuebunny/crossref_metadata_2025 huggingface dataset:
Mobilitätsgenossenschaften als Ergänzung des nachhaltigen Mobilitätsangebots in großen Organisationen
Authors: Roos Michael
Published: September 2024

Ein wichtiger Hebel, um unsere Mobilität nachhaltiger zu gestalten, ist der Berufsverkehr. Mehr als die Hälfte der Beschäftigten fahren tagtäglich mit dem eigenen Pkw zur Arbeit – meistens ­allein. Mobilitätsgenossenschaften, die die ­gemeinsame Nutzung von Fahrzeugen organisieren, sind hier ein vielversprechendes Konzept. Wie dieses­ Konzept auch in großen Organisationen umgesetzt werden kann, zeigt das Beispiel der Ruhr-Universität Bochum.
Algunas reflexiones para evaluar la accesibilidad en los modelos latinoamericanos de gobierno digital
Authors: Prada Uribe Julián Eduardo
Published: September 2024

En un principio, la institucionalización de los gobiernos digitales dependió de la voluntad política de los Estados y de previsiones económicas tendientes a disponer de los recursos necesarios en el campo de las comunicaciones. Hoy, uno de sus ejes, no solo nacional sino también internacional, aparte del mejoramiento de la calidad de los servicios y funciones, pertenece a la esfera de la inclusión, es decir, a la capacidad de penetración social, la generación de confianza entre los usuarios, los incentivos a favor de la gobernanza y el empoderamiento civil en ambientes virtuales. Este trabajo reconoce que, si bien en los países latinoamericanos se ha avanzado en la creación de un marco social, político y jurídico para el cumplimiento de la agenda digital, en la informatización de procesos y en la búsqueda de soluciones desde una perspectiva intergubernamental, todavía existen dudas en torno a la noción de accesibilidad, que demandan la construcción de instrumentos para medir la fortalezas y debilidades de las políticas públicas y, en especial, de su aplicación.
Participación ciudadana y el orden político resultante de las reformas administrativas y constitucionales
Authors: Córdova Jaimes Edgar
Published: September 2024

El trabajo tiene por objetivo reflexionar sobre la participación ciudadana y sus realizaciones a partir de las reformas administrativas y constitucionales experimentadas en las décadas de los años ochenta y noventa en Venezuela y Colombia. Metodológicamente se hace una revisión documental para establecer la relación entre la participación ciudadana como pilar de las reformas administrativas-constitucionales y sus realizaciones tendientes a repolitizar la ciudadanía, o que pretenden un orden político más democrático que el modelo de democracia representativa. Se analizan los contextos de los casos de Colombia y Venezuela con el fin de establecer los cambios operados a favor del nuevo orden político. Se analizó información y datos producidos por científicos sociales, así como por organismos públicos e internacionales, dispuestos en sistemas de Open Access. Se concluye que la participación ciudadana muestra un fuerte desarrollo legislativo-formal. Sin embargo, dinámicas de orden político y económico han terminado por establecer barreras para su realización política, convirtiéndose aún en una debilidad destacable del modelo que en principio se funda precisamente en la existencia de una densa y sustentable participación ciudadana.
Learning to change the world
Authors: Bronkhorst Larike , Renes Marlon , Bon Dagmar , Rookmaker Noah , Van Leest Anne
Published: September 2024

Feeling the urgency of the climate crisis and judging current societal (re)action insufficient, young adults increasingly engage in climate activism. While individual learning is not the objective of climate activism, research has documented that young adults learn in climate activism movements. This study traces young adults’ learning across climate activism and different life-wide contexts, explicating dis/continuities in learning. Content-analysis of interviews with twelve self-defined climate activists indicates that in and across climate activism and other life-contexts young adults report a) learning about the climate, activism, intersectionality, democracy and system structures, b) learning to organize, socialize and take perspective(s), while c) progressively expressing who and how they want to be(come). Young adults described experiencing discontinuities between the context of their climate activism and other contexts such as education, friends and family, and their efforts to re-establish continuities are an important part of their learning. When young adults experience discontinuity across contexts structurally, they keep their climate activism to themselves and/or disengage from education, among others. Making space in education more explicitly for sharing and shaping what matters to youth seems desirable.
Sex and disease regulate major histocompatibility complex class I expression in human lung epithelial cells
Authors: Mathé Justine , Brochu Sylvie , Adam Damien , Brochiero Emmanuelle , Perreault Claude
Published: September 2024

Major histocompatibility complex class I (MHC I) molecules present peptides to CD8+ T‐cells for immunosurveillance of infection and cancer. Recent studies indicate lineage‐specific heterogeneity in MHC I expression. While respiratory diseases rank among the leading causes of mortality, studies in mice have shown that lung epithelial cells (LECs) express the lowest levels of MHC I in the lung. This study aims to answer three questions: (i) Do human LECs express low levels of MHC I? (ii) Is LEC MHC I expression modulated in chronic respiratory diseases? (iii) Which factors regulate MHC I levels in human LECs? We analyzed human LECs from parenchymal explants using single‐cell RNA sequencing and immunostaining. We confirmed low constitutive MHC I expression in human LECs, with significant upregulation in chronic respiratory diseases. We observed a sexual dimorphism, with males having higher MHC I levels under steady‐state conditions, likely due to differential redox balance. Our study unveils the complex interplay between MHC I expression, sex, and respiratory disease. Since MHC I upregulation contributes to the development of immunopathologies in other models, we propose that it may have a similar impact on chronic lung disease.
Radiogenomics based survival prediction of small-sample glioblastoma patients by multi-task DFFSP model
Authors: Fu Xue , Chen Chunxiao , Chen Zhiying , Yu Jie , Wang Liang
Published: September 2024

In this paper, the multi-task dense-feature-fusion survival prediction (DFFSP) model is proposed to predict the three-year survival for glioblastoma (GBM) patients based on radiogenomics data. The contrast-enhanced T1-weighted (T1w) image, T2-weighted (T2w) image and copy number variation (CNV) is used as the input of the three branches of the DFFSP model. This model uses two image extraction modules consisting of residual blocks and one dense feature fusion module to make multi-scale fusion of T1w and T2w image features as backbone. Also, a gene feature extraction module is used to adaptively weight CNV fragments. Besides, a transfer learning module is introduced to solve the small sample problem and an image reconstruction module is adopted to make the model anatomy-aware under a multi-task framework. 256 sample pairs (T1w and corresponding T2w MRI slices) and 187 CNVs of 74 patients were used. The experimental results show that the proposed model can predict the three-year survival of GBM patients with the accuracy of 89.1 %, which is improved by 3.2 and 4.7 % compared with the model without genes and the model using last fusion strategy, respectively. This model could also classify the patients into high-risk and low-risk groups, which will effectively assist doctors in diagnosing GBM patients.
Verb influence on French wh-placement: a parallel corpus study
Authors: Fliessbach Jan , Rockstroh Johanna
Published: September 2024

Our study investigates the effect of French verb lemmata on the preverbal (QV) or postverbal (VQ) positioning of interrogative forms equivalent to English ‘what’ (que, quoi, and related forms) within a French–Spanish parallel corpus of subtitles. We highlight and illustrate the corpus’s utility for studying less frequent verbs in combination with specific wh-forms. Our findings suggest that less frequent French verbs exhibit weaker associations with QV compared to their more frequent counterparts. A post-hoc study using Spanish translations reveals that French verbs correlated with QV often denote observable actions involving directly accessible Q-referents. We hypothesise that queries concerning ‘situationally accessible’ referents are predominantly utilised for non-standard, evaluative, or challenging questions, which are typically QV in French.
Lipschitz regularity of sub-elliptic harmonic maps into CAT(0) space
Authors: Assimos Renan , Gui Yaoting , Jost Jürgen
Published: September 2024

We prove the local Lipschitz continuity of sub-elliptic harmonic maps between certain singular spaces, more specifically from the 𝑛-dimensional Heisenberg group into

CAT
⁡

(
0
)

\operatorname{CAT}(0)

spaces.
Our main theorem establishes that these maps have the desired Lipschitz regularity, extending the Hölder regularity in this setting proven in [Y. Gui, J. Jost and X. Li-Jost, Subelliptic harmonic maps with values in metric spaces of nonpositive curvature, Commun. Math. Res.
38 (2022), 4, 516–534] and obtaining same regularity as in [H.-C. Zhang and X.-P. Zhu, Lipschitz continuity of harmonic maps between Alexandrov spaces, Invent. Math.
211 (2018), 3, 863–934] for certain sub-Riemannian geometries; see also [N. Gigli, On the regularity of harmonic maps from

RCD
⁢

(
K
,
N
)

\mathrm{RCD}(K,N)

to

CAT
⁢

(
0
)

\mathrm{CAT}(0)

spaces and related results, preprint (2022), https://arxiv.org/abs/2204.04317; and A. Mondino and D. Semola, Lipschitz continuity and Bochner–Eells–Sampson inequality for harmonic maps from

RCD
⁡

(
k
,
n
)

\operatorname{RCD}(k,n)

spaces to

CAT
⁡

(
0
)

\operatorname{CAT}(0)

spaces, preprint (2022), https://arxiv.org/abs/2202.01590] for the generalisation to RCD spaces.
The present result paves the way for a general regularity theory of sub-elliptic harmonic maps, providing a versatile approach applicable beyond the Heisenberg group.
Analysis of cell cycle stage, replicated DNA, and chromatin-associated proteins using high-throughput flow cytometry
Authors: Bejarano Franco Marina , Boujataoui Safia , Hadji Majd , Hammer Louis , Ulrich Helle D. , Reuter L. Maximilian
Published: September 2024

Flow cytometry is a versatile tool used for cell sorting, DNA content imaging, and determining various cellular characteristics. With the possibility of high-throughput analyses, it combines convenient labelling techniques to serve rapid, quantitative, and qualitative workflows. The ease of sample preparation and the broad range of applications render flow cytometry a preferred approach for many scientific questions. Yet, we lack practical adaptations to fully harness the quantitative and high-throughput capabilities of most cytometers for many organisms. Here, we present simple and advanced protocols for the analysis of total DNA content, de novo DNA synthesis, and protein association to chromatin in budding yeast and human cells. Upon optimization of experimental conditions and choice of fluorescent dyes, up to four parameters can be measured simultaneously and quantitatively for each cell of a population in a multi-well plate format. Reducing sample numbers, plastic waste, costs per well, and hands-on time without compromising signal quality or single-cell accuracy are the main advantages of the presented protocols. In proof-of-principle experiments, we show that DNA content increase in S-phase correlates with de novo DNA synthesis and can be predicted by the presence of the replicative helicase MCM2-7 on genomic DNA.
Allergic reactions to enzyme replacement therapy in children with lysosomal storage diseases and their management
Authors: Arik Elif , Keskin Özlem , Albayrak Serpil , Keskin Mehmet , Cesur Mahmut , Karaoglan Murat , Inal Gaye , Yildirim Ahmet , Kucukosmanoglu Ercan
Published: September 2024

Objectives

Human recombinant enzyme replacement therapy, given to compensate for genetic enzyme deficiency in lysosomal storage diseases, delays the progression of the disease and improves the quality of life. However, enzyme replacement therapy may cause hypersensitivity reactions. Within the scope of this research, we aimed to elucidate the frequency and clinical features of hypersensitivity reactions against enzyme replacement therapy in children with lysosomal storage diseases and clarify the management of these reactions.

Methods

Medical records of pediatric patients with lysosomal storage disease and receiving enzyme replacement therapy were retrospectively reviewed, and patients who experienced allergic reactions were included in the study. The demographic characteristics of the patients, their diagnosis, the responsible enzyme, the time at which the reaction started and at what dose, the signs and symptoms associated with the reaction, diagnostic tests, the management of the reaction, and the protocol applied for the maintenance of enzyme replacement therapy after the reaction were recorded.

Results

Hypersensitivity reactions developed in 18 of 71 patients (25.3 %) who received enzyme replacement therapy. The most common cutaneous findings were observed. Anaphylaxis developed in 6 of 18 patients. Patients who experienced recurrent hypersensitivity reactions with premedication or a slower infusion rate, those with positive skin test results, and patients who developed anaphylaxis were given enzyme replacement therapy with desensitization.

Conclusions

HSR may develop during enzyme replacement therapy, which are vital in lysosomal storage diseases, and discontinuation of enzyme replacement therapy is a significant loss for patients with metabolic disorders. These reactions can be treated with premedication and long-term infusions, but some patients may require desensitization protocols for continued treatment.
An unconditionally stable numerical scheme for solving nonlinear Fisher equation
Authors: Vimal Vikash , Sinha Rajesh Kumar , Liju Pannikkal
Published: September 2024

In this study, novel numerical methods are presented for solving nonlinear Fisher equations. These equations have a wide range of applications in various scientific and engineering fields, particularly in the biomedical sciences for determining the size of brain tumors. The challenges posed by the nonlinearity of the equations are effectively addressed through the development of numerical techniques. The nonlinearity is tackled using a combination of the method of lines and backward differentiation formulas of varied orders. This method is unconditionally stable, and its accuracy is evaluated using error norms. The methods are successfully validated against test problems with known solutions, demonstrating their superiority through comparative analyses with existing methodologies in the literature.
Grenzen – Beiträge zur Genealogie eines Konzepts
Authors: Ricken Norbert
Published: September 2024

Vor dem Hintergrund einer veränderten gesellschaftlichen Bedeutung von ,Grenzen‘ widmet sich der Beitrag der Auseinandersetzung mit ,Grenze‘ als einem kulturellen Topos. Gerade weil das, was mit ,Grenze‘ aufgerufen wird, alles andere als eindeutig und über die Zeit stabil verfasst (gewesen) ist, lohnt sich ein genealogischer Blick auf die ,Grenze‘. Dabei tauchen dann nicht nur Fragen auf, was denn jeweilig unter ,Grenze‘ verstanden wird und worden ist, sondern auch, was sich über die Bedeutung und Funktion des Konzepts der Grenze, über die Logik des Be- und Entgrenzens, sagen lässt. Nach einer kurzen begriffsgeschichtlichen Auseinandersetzung (1) geht es unter dem Stichwort der ,Grenzregime‘ um drei typologische Praktiken der Grenzziehung, -verschiebung und -aufhebung und ihre jeweiligen Logiken (2), bevor schließlich einige systematische Folgerungen gezogen und Unterscheidungen getroffen werden (3).
Entgrenzungen und Begrenzungen
Authors: Krebs Moritz , Schamel Liesa
Published: September 2024

Anliegen des Beitrags ist es, besondere Veränderungen in den Grundlagen von Erfahrung und Erkenntnis durch Prozesse der Digitalisierung als dialektisches Verhältnis von Entgrenzung und Begrenzung auszuweisen. Dazu werden zunächst Aspekte dieses Verhältnisses auf gesellschafts- und kulturtheoretischer Ebene herausgestellt. Dadurch geraten Ideologie und Realität des Digitalen in den Blick. Im Hinblick auf die Sozialität des Digitalen werden die Widersprüche zwischen den Verheißungen auf Erfüllung sozialer Bedürfnisse und ihrer Realisierung thematisiert.
Free vibration analyses of 3D printed plates with different geometric fillings: experimental testing and numerical simulations
Authors: Yildiz Ahmet , İbram Emre , Erol Onur , Güler Özgül Hande
Published: September 2024

In this article, the numerical and experimental free vibration analyses of PLA-based composite plates with different filling geometries were carried out. Firstly, the natural frequencies and modal shapes were obtained from finite element (FE) methods to characterize the vibration behavior of the plates. The obtained results were compared with experimental testing of the three-dimensional (3D) produced plates. In the comparison, it was seen that the finite element analysis and the experimental results were quite close to each other. It was also observed that the highest frequencies are measured by a triangle, then the grid and honeycomb. Moreover, higher frequencies and lower weights are possible with the triangle pattern fill. On the other hand, it is noted that the types of filling structures do not affect the modal shapes of the 3D plates. Thus, the results of this paper are of utmost importance for getting light structure and high frequencies.
How to Maximize a Single Session? From a Reflection on Theoretical Pluralism to the Definition of Five Goals
Authors: Cannistrà Flavio
Published: September 2024

Single-session therapy (SST) is a kind of intervention that aims to maximize the effectiveness of each individual therapy session, which may often prove to be the only session. For this reason, it is essential to identify the goal to be reached by the end of the session. However, this may be limited by the lack of a precise theoretical framing for SST. This article will illustrate a framework known as “theoretical pluralism” within which the use of SST can be placed. This will be followed by the proposal of a possible mode of intervention that can help therapists answer the question: “How can I help the patient achieve the goal of this session?”
Remembering the Future: Situating Oneself in a Constantly Evolving Field
Authors: Dickerson Victoria C.
Published: September 2024

Fields of knowledge are constantly evolving. The postmodern turn in the social sciences and the influence of social constructionism have greatly affected the field of family therapy over the past 30 years. In this retrospective view of the evolution of family therapy, I examine some of the critical changes, including not only major theoretical considerations but also sociopolitical issues. I question the current state of family therapy education, and I further raise the question of how a postmodern, social constructionist, narrative approach can serve our students and our clients. I propose that not only situating ourselves in the epistemology that is shaping us but also maintaining a questioning stance that allows us to continually ask ourselves in what discourse we are standing will serve us well, not only now in times of uncertainty but perhaps far into the future.
NAR SUYUNUN ALJİNAT KÜRECİKLERİ İLE ENKAPSÜLASYONU: İŞLEM KOŞULLARININ OPTİMİZASYONU
Authors: Balcı Torun Ferhan
Published: September 2024

Bu çalışmada nar suyunun aljinat kürecikleri ile enkapsülasyonunda işlem parametrelerinin elde edilen kapsüllerin bazı fiziksel ve kimyasal özellikleri üzerine etkisi incelenmiştir. Enkapsülasyon işleminin optimizasyonunda aljinat konsantrasyonu, CaCl2 konsantrasyonu, damlama hızı ve damlama yüksekliği bağımsız işlem değişkenleri olarak, kapsüllerin şekil faktörü, küreselliği ile toplam fenolik madde ise bağımlı değişkenler olarak seçilmiştir. Optimizasyon sonunda en uygun işlem koşulları aljinat konsantrasyonu %1.6, kalsiyum konsantrasyonu %3, damlama hızı 0.77 ve damlama yüksekliği 10 cm olarak belirlenmiştir. Sonuçlar mikrokapsüllerin fiziksel ve kimyasal özelliklerinin farklı işlem koşullarından etkilendiğini göstermiştir. Damlama hızı ve yüksekliğinin artması ile kapsüllerin şeklinin mükemmel küreselliğe yaklaştığı, aljinat konsantrasyonunun artmasının ise damlacıkların küreselliğinin bozulmasına neden olduğu görülürken, aljinat konsantrasyonu ile damlama yüksekliğinin azalmasının elde edilen kapsüllerin toplam fenolik madde miktarını olumlu yönde etkilediği sonucuna ulaşılmıştır.
Moderne Tracking-Methoden im Online-Marketing
Authors: Hoffmann Sascha , Wigbels Markus
Published: September 2024

Für ein effektives Online-Marketing ist eine zielgruppenspezifische Aussteuerung von Werbemitteln essentiell. Dazu werden intensiv Informationen zu den Interessen und Vorlieben von Internetusern genutzt. Diese werden insbesondere durch die Analyse ihres Surfverhaltens gewonnen. Das primär zum Einsatz kommende Verfahren ist dabei das Third-Party-Cookie Tracking, das jedoch immer weiter eingeschränkt wird. Im Beitrag werden mit First-Party-Tracking, Browser-Targeting sowie User ID-Verfahren moderne, datenschutzkonforme Alternativen vorgestellt.
Badwill bei Unternehmensübernahmen
Authors: Halm Christian , Rogler Silvia , Horsch Andreas
Published: September 2024

Im Rahmen von Unternehmensübernahmen zahlt der Akquisiteur regelmäßig Kaufpreise, die höher sind als das Reinvermögen. Verglichen mit diesem insoweit üblichen Goodwill sind negative Unterschiedsbeträge eher die Ausnahme. Umso interessanter sind die Fragen, die hieraus für verschiedene betriebswirtschaftliche Teildisziplinen, allen voran Rechnungswesen und Finanzwirtschaft, resultieren. Ausgehend vom spektakulären Fall der Credit Suisse und ihrer letztlichen Übernahme durch die UBS im ersten Halbjahr 2023, welche durch einen extremen Badwill gekennzeichnet war, wird der Badwill als solcher sowie im Hinblick auf seine Bilanzierung und Bewertung beleuchtet.
Wechsel des Geschäftsjahres in einem handelsrechtlichen Jahresabschluss und einem Jahresabschluss nach IFRS
Authors: Roos Benjamin
Published: September 2024

Ein einmal festgelegtes Geschäftsjahr kann nicht willkürlich gewechselt werden. Dennoch besteht unter bestimmten Voraussetzungen die Möglichkeit hierzu. Aufgrund der unterschiedlichen Ausgestaltung der Vorgehensweise im HGB und den internationalen Standards können sich hier, gerade für deutsche IFRS-Bilanzierer, herausfordernde Konstellationen ergeben.
Bilanzierung negativer Unterschiedsbeträge bei Unternehmensübernahmen
Authors: Thümmler Stefanie , Rogler Silvia , Horsch Andreas
Published: September 2024

Im Rahmen von Unternehmensübernahmen kommt es regelmäßig zu Unterschiedsbeträgen zwischen Kaufpreis und Substanzwert. Fallen diese negativ aus, werden sie als Badwill bezeichnet. Wie am aktuellen Beispiel der Übernahme der Credit Suisse durch die UBS zu sehen (vgl. Halm/Horsch/Rogler, in WiSt-Heft Nr. 5, 2024), wird das Auftreten solcher Unterschiedsbeträge auch in der breiten Öffentlichkeit diskutiert, da damit hohe Buchgewinne einhergehen können. Der folgenden Fallstudie liegt eine solche Unternehmensübernahme zugrunde. Vor diesem Hintergrund werden verschiedene Fragestellungen rund um die Ermittlung und Bilanzierung des Badwill nach IFRS diskutiert. Die Lösungen werden in der folgenden WiSt-Ausgabe (Nr. 7–8/2024) präsentiert.
Central Bank Digital Currencies - Nutzen und Kosten
Authors: Vollmer Uwe
Published: September 2024

Viele Notenbanken prüfen derzeit, ob sie zukünftig Zentralbankgeld in digitaler Form („Central Bank Digital Currency“ – CBDC) ausgeben sollen. Es soll Bargeld und Notenbankeinlagen um eine dritte Erscheinungsform ergänzen, über die online und offline verfügt werden kann. Auch das Eurosystem will in den kommenden beiden Jahren endgültig entscheiden, ob es einen „digitalen Euro“ ausgeben wird. Der Beitrag fragt nach den Gründen, warum Notenbanken die Emission von digitalem Zentralbankgeld prüfen, und diskutiert mögliche Risiken, die in einer Disintermediation und in Risiken für die Finanzmarktstabilität bestehen.
Café tostado de Costa Rica
Authors: Díaz-Porras Rafael , Jiménez-Porras Gerardo , Delgado-Ballesteros Antonio
Published: September 2024

This article analyzes the dynamics of the roasted coffee industry in Costa Rica, which has been an innovation in the recent coffee activity. This is evidenced by examining the objectives, strategies and organization of coffee roasting companies in Costa Rica. The article systematizes previous studies on the structure of the roasted coffee industry in Costa Rica, consumer behavior, and information that was extracted from regional analysis cases. The results point to the characterization of the companies, their supply chain, and the operation in the local spaces as contributions to local development. Finally, policy recommendations are made to the institutions and the roasting sector that account for the invigoration of this industry.
Exploraciones en el paisaje onomástico de Ixtlahuaca, México: el caso de los urbanónimos
Authors: Reyes Contreras Miguel , Serrano Morales Julio César
Published: September 2024

A paisagem onomástica é uma variante específica da paisagem linguística (Landry & Bourhis, 1997) a qual, por sua vez, é uma derivação dos estudos da paisagem da geografia e do urbanismo. Seu objeto de estudo é a presença de nomes próprios em determinados espaços públicos cuja função é identificar, divulgar e comemorar. Compreendendo que a paisagem linguística representa lugares específicos no ambiente geográfico, este trabalho se baseia na função comemorativa do nome do lugar sob o ponto de vista de Azaryahu (2012a, 2012b), Rose-Redwood et al. (2018), Rose-Redwood & Sun-Bae (2020) e Alderman (2020) como forma de legitimar um contexto político. Utilizando essa delimitação conceitual, o objetivo do trabalho é analisar um corpus de 309 nomes de escolas, entendidos como urbanônimos. O corpus de análise foi construído com os resultados de busca de dados no portal da Secretaría de Educación del Estado de México que concentra todas as escolas por município. Apresenta-se a discussão dos resultados da análise preliminar sobre o léxico em geral e o léxico onomástico e discute-se como o processo de nomeação das escolas revela uma visão da história e cultura nacional e local, especialmente do período revolucionário e do México moderno.
Iconicidad, isomorfismo y lengua de señas
Authors: Casas Navarro Raymundo
Published: September 2024

Se asumía que la arbitrariedad del signo era un atributo esencial del lenguaje y ello implicó un menoscabo de la iconicidad en la historia de la lingüística moderna. Recientemente, hay estudios que propugnan un equilibrio en el entendimiento de la naturaleza del lenguaje. Así, la iconicidad también desempeña un rol preponderante en la estructura y funcionamiento del simbolismo humano, razón por la cual se necesita examinar el postulado raigal de la arbitrariedad. Tanto en la filogenia como en la ontogenia, la iconicidad desempeña un rol axial en las configuraciones verbales de todas las lenguas. Se postula que la arbitrariedad y la iconicidad despliegan un principio más profundo: el isomorfismo. Una de las condiciones del principio es la trayectoria oscilante desde un origen motivado hasta un estadio arbitrario. Si bien la arbitrariedad se relaciona con la eficiencia y la sutileza de la gramática, la iconicidad es gravitante para establecer el vínculo entre el lenguaje, la cognición y el acervo experiencial humano. Para demostrar que tanto la iconicidad como la arbitrariedad son rasgos determinantes del lenguaje, se hurgará en la investigación científica en torno a las diferentes lenguas de señas del mundo, puesto que en las lenguas signadas resulta perspicua la iconicidad.
Ministerio de Educación. Lengua de señas peruana: Guía para el aprendizaje de la lengua de señas peruana, vocabulario básico
Authors: Napan Gómez Karen
Published: September 2024

El Poder Ejecutivo aprobó el 18 de mayo de 2010 la Ley 29535 que otorga reconocimiento oficial a la lengua de señas peruana. Esta ley fue publicada el 21 de mayo de 2010 y un poco más de 7 años después, el lunes 14 de agosto de 2017, se aprobó mediante Decreto Legislativo N.° 006-2017-MIMP el reglamento de la Ley 29535. Este constructo legal reconoce la lengua de señas peruana como la lengua de las personas con discapacidad auditiva en todo el territorio nacional y comprende los sistemas lingüísticos de carácter visual, espacial, gestual y manual.
On the distributions of additive functions
Authors: Šiaulys Jonas
Published: September 2024

There is not abstract.
α-normal distribution
Authors: Kanišauskas Vaidotas
Published: September 2024

In this paper I introduce and consider the new class of distributions  –  natural widening of normal distribution.
Internal averaging of gas dinamic equations
Authors: Krylovas Aleksandras
Published: September 2024

An asymptotical approximation of a solution of a system of equations which describe one dimensional gas flow depending on a small parameter is obtained.
Les structures presque produit dans l'espace métrique des éléments hyperplaniques
Authors: Katinienė Irena
Published: September 2024

Dans cet article on étudie l'espace métrique d'éléments d'appuis dont élément d'appuis est un hyper­plan. Du tenseur métrique et ces prolongements partiels on a reçu dix diférents structures presque produit de cet espace.
La géométrie de l'espace des éléments d'appuis Yn
Authors: Pakalnyté Jolita , Urbonas Algimantas Pranas
Published: September 2024

L'espace Yn des éléments d'appuis dont un élément' dàppui est un objet du deuxième ordre. On dévelope la théorie de courbure de cet espace à connexion linéaire et on trouve des courbes géodésiques.
Problems and achievements of the country's first mathematics contest of the pupils of fourth form
Authors: Kiseliova Danutė , Kiseliovas Arkadijus
Published: September 2024

In the article the achievement, results and problems of the Country's first contest of the pupils of fourths form have been presented and analysed.
Specialization of loop rules of a sequent calculus of intuitionistic temporal logic with time gaps
Authors: Alonderis Romas
Published: September 2024

There is not abstract.
Adaptive estimation: a brief review
Authors: Radavičius Marijus
Published: September 2024

There is not abstract.
Numerical method for a Schrödinger problem with amplification process
Authors: Čiegis Raimondas , Kairytė Genė , Pakalnytė Violeta
Published: September 2024

In this paper we consider one Schrödinger problem which describes a signal propagation in optical fibers. The stability of symmetrical finite difference scheme is investigated in the L2 norm. It is proved that the scheme becomes unstable if the signal is periodically amplified along the fiber. A modification of the symmetrical scheme and one splitting scheme are proposed to solve the given problem.
Numerical algorithm for integrals with rapid oscilatory functions
Authors: Čiegis Raimondas , Šablinskas Ramūnas
Published: September 2024

In this paper we consider numerical integration of rapid oscilatory functions for the laser beam diffrac­tion field calculation problem. Two different methods are proposed and the accuracy of approximations are investigated. Numerical experiments are presented and analysed.
Calculation of bending deflection and stresses of a pipe with flowing fluid in the case of variable ground load
Authors: Didžgalvis Rimantas , Sudintas Antanas , Tiknevičienė Irena
Published: September 2024

The mathematical model of the oscillations of fulfilled pipe is formed on the case when that pipe suddenly losses the support. Using the methods of approximate solutions of differential equations, the analytical pipe bend dynamic expressions were given at the case, when the ground load minimises expo­nentially. Finally, those solutions could be used for the finding more exact normal tensions in the wall of the pipes, when the reological parameters of the ground are determined.
The infection spread model among grouped drug users
Authors: Tiešis Vytautas
Published: September 2024

The stochastic model of an infection spread among intravenous drug users was built in the case when a group of drug users shares one filled syringe. The impact of various factors to the rate of spread was investigated by the stochastic simulation.
Аппроксимация нормальным законом функции распределения и ее плотности нелинейного преобразования стационарного гауссовского процесса
Authors: Saulis Leonas
Published: September 2024

There is not abstract.
Refinement of the L1 estimate in the central limit theorem for m-dependent random fields
Authors: Sunklodas Jonas
Published: September 2024

There is not abstract.
On strongly prime ideals, strongly multiplicative and insulating sets in rings
Authors: Kaučikas Algirdas
Published: September 2024

There is not abstract.
Challenges and paradoxes in mental health care for transgender people in Brazil: a review of historical contexts and narratives
Authors: Ribeiro Marques Luciana , Alberti Sonia , Ferreira da Silva Heloene , Solano Pamela , Mählmann Muniz Dantas Priscila
Published: September 2024

Individualized interviews with transgender people reveal diverse experiences, offering unique data for mental health care providers. These narratives challenge psychopathological categories and highlight the need for deeper investigation. The study aims to address these experiences comprehensively, understand the importance of each transgender narrative, and counteract biased approaches. Understanding the historical context of transgender assistance in Brazil is crucial. This context reveals a paradox: the need for individualized listening versus the standardization of transgender individuals under "conditions related to sexual health" in ICD-11. Brazil leads in transgender murders. Violence against this population stems from prejudices, ignorance, and pathologization, as historical evidence shows. We consider it essential to investigate these causes further and contribute by listening to this population, revealing the diversity in their experiences. A literature review of articles from 2011 to 2021 in Brazil identified 29 publications on transgender issues and psychology. This qualitative research used refined scales to address diverse transgender experiences, reducing result generalization. The historicization of the problems faced by transgender people in Brazil and the verification of the particularities revealed in the narrative of each participant are necessary counterpoints to the segregation and critical situation of this population in the country. By synthesizing individualized narratives, historical context, and literature, this study contributes to improving mental health care and social support for transgender individuals, emphasizing the importance of individualized listening and culturally sensitive approaches to reduce stigmatization and promote depathologization.
Features of Bioluminescence Dynamics of Photobacterium phosphoreum IMV B-7071
Authors: Gromozova O.M. , Martynyuk V.S. , Artemenko O.Yu. , Hretskyi I.O. , Mulec Janez , Tseyslyer Yu.V.
Published: September 2024

The problem of the prolonged and stable intensity of bioluminescent signals is relevant in the development of any test systems that use biological objects. The aim of this work was to study the features of bioluminescence dynamics of Photobacterium phosphoreum IMV B-7071 in a liquid and on different stationary media. Methods. Bioluminescence studies were performed in liquid, agarose, and cellulose-cotton media. Bacterial suspensions were cultivated at 21°C in the mediums with standard composition. We studied both the background glow and its dynamics under conditions of mixing a liquid medium. Bioluminescence was recorded using digital photography with subsequent image processing of the samples. The measurements of luminescence were made by digital photo or video recording using Olympus digital camera SP560UZ, CANON 700D, and mobile device camera Samsung Galaxy 9 Note with specialized applications for mobile devices "Colorimeter (Lab Tools Apps)" and Camera Color Counter (Keuwsoft) at maximum light sensitivity in the automatic white balance mode at a fixed distance from the sample. Image processing was carried out using ImageJ and Origin Pro. Spectra of bacterial luminescence and its dynamics over time were measured using an LOMO MDR-23 spectrometer in the range of 200–750 nm. Results. The results of the study prove that in aqueous or solid agar and also on cellulose cotton medium, the intensity of bioluminescence of P. phosphoreum gradually increases, reaching a maximum within approximately 2 days, after which it slowly fades. It was established that the bioluminescence of photobacterium P. phosphoreum is a non-stationary process and has characteristic features of temporal dynamics associated with both the dynamics of the oxygen concentration in the environment of bacterial suspensions and the dynamics of the bacterial population density. Analysis of the luminescence spectra of bacteria shows that luminescence occurs mainly in the blue and green regions of the spectrum with luminescence maxima in the range of 460–520 nm, but the ultra-weak glow is also registered in the UV and red spectral ranges. The variability of photobacterial luminescence spectra over time in the spectral ranges of the main luminophores causes color fluctuations between the blue and green ranges. Conclusions. The key parameters of multi-day background and short-term induced bioluminescence dynamics of photobacteria in different environments were clarified, and the certain variability of the spectral characteristics of luminescent radiation over time was shown. The revealed features of the dynamics of the bioluminescence of P. phosphoreum must be taken into account in practical application to assess the toxicity of substances of various nature, as well as in environmental monitoring.
Корекція пробіотиком пародонтального синдрому у тварин за умов ожиріння і хронічного стресу
Authors: Цебенко М.О. , Білець М.В. , Омельченко О.Є. , Євтушок В.В. , Непорада К.С. , Лазаренко Л.М.
Published: September 2024

The aim of this study was to investigate the effect of obesity and chronic stress on periodontal tissues, both separately and in the combined comorbidity of these conditions in rats, and the role of the probiotic Lactobacillus casei in the correction of periodontal syndrome under these conditions. Methods. The development of periodontal syndrome and the effectiveness of the probiotic Lactobacillus casei IMV B-7280, administered to rats from one month of age intragastrically in a volume of 1 mL (5 · 108 CFU) in two-week courses with breaks of 2 weeks, were studied in a model of glutamate-induced obesity and chronic stress - in combination and separately. In periodontal tissues, the total proteolytic and antitryptic activity, free fucose and glycosaminoglycans (GAG) content, catalase activity, thiobarbiturate active products (TBA reagents), and the content of oxidatively modified proteins (OMP) and molecules of average mass (AMM) were determined; in bone tissue, the molar root exposure coefficient was calculated. The anthropometric parameters of the animals and the Selye triad were studied. Results. We have substantiated the development of periodontal syndrome in animals with glutamate-induced obesity against the background of chronic stress, as evidenced by the activation of free radical oxidation of lipids and proteins, depolymerization of fucoproteins and proteoglycans of periodontal connective tissue, which causes exposure of molar roots by almost 65%. The administration of the probiotic Lactobacillus casei in two-week courses with intervals of 2 weeks to obese rats with chronic stress prevented the development of obesity, as evidenced by a significant decrease in visceral fat mass, Li index, and BMI, as well as the severity of stress syndrome, as evidenced by a decrease in ulcer formation, thymus involution, and adrenal hypertrophy. The periodontoprotective effect of Lactobacillus casei under the combined influence of obesity and chronic stress was proved by significant changes in oxidative stress, free fucose, and GAG content and a 1.5-times decrease in the molar root exposure ratio. Conclusions. Periodic administration of Lactobacillus casei to rats treated with sodium glutamate in the neonatal period against the background of chronic stress prevented the development of obesity, the severity of stress syndromeб and damage to periodontal tissues, as evidenced by the prevention of oxidative stress, increased catabolism of extracellular connective tissue proteins and antiresorptive effect.
A Coproduced Family Reporting Intervention to Improve Safety Surveillance and Reduce Disparities
Authors: Khan Alisa , Baird Jennifer , Mauskar Sangeeta , Haskell Helen W. , Habibi Alexandra N. , Ngo Tiffany , Aldarondo Alexandra , Berry Jay G. , Copp Katherine L. , Liu Jessica P. , Elder Brynn , Gray Kathryn P. , Hennessy Karen , Humphrey Kate E. , Luff Donna , Mallick Nandini , Matherson Susan , McGeachey Amanda G. , Melvin Patrice , Pinkham Amy L. , Quiñones-Pérez Bianca , Rogers Jayne , Singer Sara J. , Stoeck Patricia A. , Toomey Sara L. , Viswanath K. , Wilder Jayme L. , Schuster Mark A. , Landrigan Christopher P.
Published: September 2024

OBJECTIVES

Examine family safety-reporting after implementing a parent–nurse–physician–leader coproduced, health literacy-informed, family safety-reporting intervention for hospitalized families of children with medical complexity.

METHODS

We implemented an English and Spanish mobile family-safety-reporting tool, staff and family education, and process for sharing comments with unit leaders on a dedicated inpatient complex care service at a pediatric hospital. Families shared safety concerns via predischarge surveys (baseline and intervention) and mobile tool (intervention). Three physicians with patient safety expertise classified events. We compared safety-reporting baseline (via survey) versus intervention (via survey and/or mobile tool) with generalized estimating equations and sub-analyzed data by COVID-19-era and educational attainment. We also compared mobile tool-detected event rates with hospital voluntary incident reporting.

RESULTS

232 baseline and 208 intervention parents participated (78.2% consented); 29.5% of baseline families versus 38.2% of intervention families reported safety concerns (P = .09). Adjusted odds ratio (95% CI) of families reporting safety concerns intervention versus baseline was 1.6 (1.0–2.6) overall, 2.6 (1.3–5.4) for those with < college education, and 3.1 (1.3–7.3) in the COVID-19–era subgroup. Safety concerns reported via mobile tool (34.6% of enrolled parents) included 42 medical errors, 43 nonsafety-related quality issues, 11 hazards, and 4 other. 15% of mobile tool concerns were also detected with voluntary incident reporting.

CONCLUSIONS

Family safety-reporting was unchanged overall after implementing a mobile reporting tool, though reporting increased among families with lower educational attainment and during the COVID-19 pandemic. The tool identified many events not otherwise captured by staff-only voluntary incident reporting. Hospitals should proactively engage families in reporting to improve safety, quality, and equity.
Neue kaiserzeitliche Inschriften aus Kibyra
Authors: Meier Ludwig
Published: September 2024

The new inscriptions published in this volume are an impressive cross-section of the prosperous urban society of Roman Imperial Cibyra. Outstanding honorary families, some of whose members were able to rise to the imperial aristocracy, stand before our eyes in desirable differentiation of their kinship relations: the Claudii Paulini, the Claudii Polemones or the hitherto unknown Flavii Captiones, who were among the builders of the impressive stadium of Cibyra. The findings of the excavations in the so-called eastern necropolis of Cibyra have contributed significantly to this. But we also encounter Roman businessmen who married local citizens’ daughters, doctors, mathematicians, ‘policemen’ and their widows, public slaves who cared little about their legally unfree status, illegitimate children adopted as foster children, or female friendships. The cabinet pieces in this volume include a complex of mosaic inscriptions in front of the Odeion of Cibyra and the funerary inscription of Indonius, the grandson and presumed adopted son of a certain Claudius Neiketes. The young man wrote his epitaph himself, playing in a charming way with the local Greek and Latin names that were used in his family and with references to the landscape that characterised the area around the village of Cibyra.
Conductors of the Belgrade Philharmonic Orchestra: A Centenary Overview
Authors: Radonjić Asja , Dujović Marijana
Published: September 2024

In 2023, a major European musical ensemble, the Belgrade Philharmonic Orchestra, celebrates its centennial. In the course of 100 years, this institution faced numerous obstacles, but thanks to the enthusiasm of great musicians, especially conductors, it has survived and laid the foundation for further musical and cultural development in Serbia. This article discusses the activity of the most important orchestral leaders (Stevan Hristić, Lovro von Matačić, Krešimir Baranović, Živojin Zdravković, Horst Förster, Vassily Sinaisky, Emil Tabakov, Uroš Lajovic, Dorian Wilson, Muhai Tang, Gabriel Feltz, Daniel Raiskin and Zubin Mehta), who have vastly contributed to or changed the course of the orchestra's development and left a big mark in its hundred-year-long history. In its centenary year, we will look back into the past, review the present, but also take a glimpse into the future the Belgrade Philharmonic Orchestra has already started to write for itself.
Low Free Thyroxine (FT4) in critically ill juvenile systemic lupus erythematosus: a diagnostic approach
Authors: Yuwono Elien , Wati Ketut Dewi Kumara , Arimbawa I Made
Published: September 2024

Introduction: Thyroid dysfunction was frequent in systemic lupus erythematosus (SLE) patients, which may present as euthyroid, hypothyroid, or hyperthyroid states. Critical conditions have a higher chance of euthyroid sick syndrome due to alterations in the hypothalamic-pituitary-thyroid (HPA) axis. Renal impairment was associated with an increased risk of low FT4 due to proteinuria followed by thyroid loss.
Case Description: We reported one patient, a 15-year-old girl, who complained of shortness of breath and revealed acute respiratory distress syndrome, valve regurgitation, and pericardial effusion. She also felt joint pain over the leg and odor urination. Further evaluation showed non-scaring alopecia, pyuria, proteinuria >0.5 gram/24 hours, urinary cast, and acute kidney injury stage failure.  ANA (IF) pattern: scattered with titer 1:100, ANA profile indicated Smith (Sm) antigen (+) and C3 108.3 mg/d, which fulfilled Systemic Lupus International Collaborating Clinics (SLICC) 2015 and European League Against Rheumatism (EULAR) 2019 criteria for SLE. On the fourth day of treatment, the patient had acute confusion, hypothermia, and sinus bradycardia, while the investigation of  FT4 hormone was 0.45 ng/dL, TSH 2.39 uIu/ml, which revealed euthyroid sick syndrome. After treatment with a high dose of methylprednisolone, cyclophosphamide, rituximab, levothyroxine, a phosphodiesterase inhibitor, and a diuretic, she deteriorated and passed away.
Conclusion: The higher prevalence of thyroid dysfunction in juvenile SLE patients necessitates further attention. Lupus nephritis, increased creatinine level, detection of Smith (Sm) antigen, and critical condition were also at higher risk of low FT4 in juvenile SLE patients. This condition may have a worsened prognosis with prompt diagnosis and treatment.