bluuebunny/crossref_metadata_2025 huggingface dataset:
Robust Adaptive Fuzzy Control via State‐Dependent Function for Nonlinear Stochastic Large‐Scale Systems Subject to Dead Zones
Authors: Zhu Chang-Qi , Liu Lei
Published: October 2021

This paper concentrates on the adaptive fuzzy control problem for stochastic nonlinear large‐scale systems with constraints and unknown dead zones. By introducing the state‐dependent function, the constrained closed‐loop system is transformed into a brand‐new system without constraints, which can realize the same control objective. Then, fuzzy logic systems (FLSs) are used to identify the unknown nonlinear functions, the dead zone inverse technique is utilized to compensate for the dead zone effect, and a robust adaptive fuzzy control scheme is developed under the backstepping frame. Based on the Lyapunov stability theory, it is proved ultimately that all signals in the closed‐loop system are bounded and the tracking errors converge to a small neighborhood of the origin. Finally, an example based on an actual system is given to verify the effectiveness of the proposed control scheme.
High Risk Features of an Anomalous Origin of the Right Coronary Artery
Authors: Campiche Dre Eleonore , Vallée Jean-Paul , Carballo David
Published: October 2021

Anomalous aortic origin of the coronary arteries (AAOCA) is a rare congenital abnormality. It is usually asymptomatic and often found incidentally during coronary angiography. However, it can also be discovered during the autopsy of young healthy adults who have suffered from sudden cardiac death (SCD). AAOCA represents the second most common cause of SCD in young athletes. Herein, we report a case of a 39-year-old patient with left-sided right coronary anomaly with multiple high-risk features who presented with life-threatening symptoms for SCD but normal electrocardiography, echocardiography, and cardiac markers. The coronary computed tomography revealed an anomalous coronary artery from the left sinus of Valsalva with a hypoplasic origin and a high-risk path between the aorta and the pulmonary artery with a short intramural path. He was surgically managed with a coronary artery bypass with an uneventful follow-up.
Robust Assessment on the Developments of Three Extended Exponential Models with Some New Properties and Applications
Authors: Ahmadini Abdullah Ali H. , Tahir Muhammad H. , Alamri Osama , Munawar Alia , Elgarhy Mohammed
Published: October 2021

The extended exponential distribution introduced by Nadarajah and Haghighi in the year 2011, which is nowadays well known as NH distribution, has received increased attention in these days. In this paper, we provide a robust assessment report on the development of three more related extended versions of exponential (or Weibull) distributions. We assessed that which model was published earlier than the other ones and why the pioneer work was not cited properly or overlooked. For example, power generalized Weibull (PGW) introduced by Bagdonavic̆ios and Nikulin (and Nikulin and Haghighi) and extended Weibull by Dimitrakopoulou, Adamidis, and Loukas, which we call here as the DAL model, were published earlier than the NH model. The developments of these three models are stated. A new method for the construction of NH and DAL models is outlined. A literature review on NH and DAL models is presented, and generalized classes from these models are discussed. Furthermore, some corrections in NH moments are suggested, and alternative expressions for moments and incomplete moments of NH and DAL models are also developed.
Comparative Analysis of Nanosilver Particles Synthesized by Different Approaches and Their Antimicrobial Efficacy
Authors: Abdelmigid Hala M. , Morsi Maissa M. , Hussien Nahed Ahmed , Alyamani Amal Ahmed , Al Sufyani Noha Moslah
Published: October 2021

Silver nanoparticles (AgNPs) were extensively used in different fields worldwide. There is a continued increase in their productions to fulfill various uses. Biological and chemical AgNP syntheses were the most popular mechanisms in this field. Agrowastes are rich in proteins, phenolics, and flavonoids that could act as bioreductant agents in AgNP biological synthesis. The present study was aimed at synthesizing AgNPs via chemical and biological methods using trisodium citrate, pomegranate fruit peel, and coffee ground waste extracts. Moreover, silver nanoparticles were monitored by UV-vis spectroscopy and characterized using zeta potential, size distribution mean, scanning electron microscope (SEM), X-ray diffractometer (XRD), and Fourier transforms infrared spectroscopy (FTIR). Four pathogenic bacterial strains (Enterobacter aerogenes, Klebsiella pneumoniae, Pseudomonas aeruginosa, and MRSA) were used to assess the antimicrobial effect of the synthesized AgNPs (2, 4, and 8 mg/ml). Results report the successful formation of silver nanoparticles chemically (AgNPs_Chem) and biologically by using pomegranate peel extract (AgNPs_PPE) and coffee ground waste extract (AgNPs_CE) due to the change of color to dark brown that is confirmed by UV-vis sharp absorption spectra at specific wavelengths. Characterization using SEM and XRD revealed their crystalline shape with a mean size of

AgNPs
_
Chem
=
62.75

,

AgNPs
_
CE
=
273.7
 
nm

, and

AgNPs
_
PPE
=
591.9
 
nm

. AgNPs_Chem show higher negativity of zeta potential (−46.7 mV) than AgNPs_CE (−12.6 mV), followed by AgNPs_PPE (−7.98 mV), which had the least stability. All the synthesized AgNPs show antimicrobial potential on all selected strains. However, 8 mg/ml shows the most effective concentration and has more efficiency on K. pneumoniae than others. Overall, the results highlight that the use of agrowastes could be an ecofriendly way to synthesize AgNPs biologically that have the same antimicrobial effect as the chemically synthesized AgNPs.
A Compact High-Power Ultra-Wideband Bipolar Pulse Generator
Authors: Wu Zhaoyang , Lu Wei , Ding Enyan , Bao Xiangyang , Yang Zhoubing , Song Falun
Published: October 2021

A compact high-power ultra-wideband bipolar pulse generator based on a modified Marx circuit is designed, which is mainly composed of a primary power supply, Marx generator, sharpening and cutoff subnanosecond spark gap switches, and coaxial transmission lines. The Marx generator with modified circuit structure has thirty-two stages and is composed of eight disk-like modules. Each module consists of four capacitors, two spark gap switches, four charging inductors, and a mechanical support. To simplify the design of the charging structure and reduce the number of switches, four groups of inductors are used to charge the capacitors of the Marx generator, two of which are used for positive voltage charging and the other two for negative voltage charging. When the capacitor of each stage is charged to 35 kV, the maximum output peak voltage can reach 1 MV when the Marx generator is open circuit. The high-voltage pulse generated by the Marx generator charges the transmission line and forms a bipolar pulse through sharpening and cutoff switches. All transmission lines used for bipolar pulse generation have an impedance of 10 Ω. When the 950 kV pulse voltage generated by the Marx generator is fed into the transmission line, the bipolar pulse peak voltage can reach 390 kV, the center frequency of the pulse is about 400 MHz, and the output peak power is about 15.2 GW.
[Retracted] Design of 3D Modeling Face Image Library in Multimedia Film and Television
Authors: Lei Di , Kim Sae-Hoon
Published: October 2021

The development of 3D modeling technology has promoted the development of the multimedia film and television industry. This article is aimed at studying the design of 3D modeling facial image library in multimedia film and television, at providing a more comprehensive facial image library for the multimedia film and television industry, at breaking the shackles of the traditional film and television industry with 3D technology, and at continuously surpassing traditional film and television media forms. This article deeply explores the background development of multimedia film and television and the characteristics of the development of new media. Starting from 3D technology, it extracts facial features of characters, transforms image data through deep autoencoders, and uses local binarization mode to perform the original facial image is subjected to texture feature extraction. In this paper, a number of experimental subjects were selected, and the subjects were photographed from the left, front, and right from multiple angles. Through the pinhole camera projection imaging process, the internal and external parameters of the camera were adjusted. In the process of 3D image construction, the image is first selected for feature detection, then the corresponding vector information and geometric conditions are matched to construct a 3D matrix, and the facial structure image is obtained by triangulation. This article compares the 3D production software on the market and selects the Maya platform suitable for building this system. The global constraint information is obtained by training some sample images. When searching the test image, find the appropriate feature point position according to the structural matching degree of the local image. When each search is completed, the global information will be used for constraint, so as to output reasonable feature information. The average residual range of the human face image constructed in this paper is 0.25‐0.45, and the maximum residual error does not exceed 4.0. The experimental method in this paper has good stability and robustness. Using the COM transmission model can make experimenters not need to think too much about the underlying details. This face animation‐driven simulation scheme can achieve more vivid facial expressions.
A Report of 61 Cases of Retroperitoneal Laparoscopic Nephron-Sparing Surgery and Factors Affecting Postoperative Renal Function
Authors: Song Yao , Pang Songqiang , Yang Jinqiang , Li Sen , He Yaqiang , Luo Gongtang
Published: October 2021

Objective. To explore the situation of 61 patients with renal tumors who underwent retroperitoneal laparoscopic nephron-sparing surgery (RLNSS) and the factors affecting postoperative renal function. Methods. A total of 61 patients with renal tumors who underwent RLNSS in our hospital from January 2018 to January 2021 were included in this study. All patients were treated with RLNSS. The clinical data of patients were recorded. Before operation and 3 months after operation, the change value of glomerular filtration rate (ΔGFR) was measured by the Gates method. Multivariate linear regression was used to analyze the related factors affecting postoperative renal function. Results. All 61 patients successfully completed the operation. The mean operative time was 60–150 min‚ average (98.75 ± 14.38) min. The estimated intraoperative blood loss was 20–310 ml‚ average (107.93 ± 68.55) ml. Intraoperative warm ischemia time (WIT) was 0–39 min, with an average of (21.16 ± 6.47) min. All patients’ pathological margins were negative after operation. In all patients, there were 5 postoperative complications, including 2 cases of renal wound bleeding (3.28%), 1 case of hematuria (1.64%), 1 case of urinary fistula (1.64%), and 1 case of subcutaneous emphysema (1.64%). There were significant differences in tumor diameter, preoperative GFR, operation time and WIT (

P
<
0.05

). Multivariate analysis showed that tumor diameter, preoperative GFR, and WIT were all factors affecting the postoperative renal function of patients with RLNSS (

P
<
0.05

). Conclusion. RLNSS has a good curative effect on patients with renal tumor, and tumor diameter, preoperative GFR, and WIT were all factors affecting the postoperative renal function of patients with RLNSS.
MDM4 Isoform Expression in Melanoma Supports an Oncogenic Role for MDM4-A
Authors: Alatawi Abdullah , Kho SoonJye , Markey Michael P.
Published: October 2021

The p53 tumor suppressor integrates upstream signals such as DNA damage and active oncogenes to initiate cell cycle arrest or apoptosis. This response is critical to halting inappropriate growth signals. As such, p53 activity is lost in cancer. In melanoma, however, the p53 gene is intact in a reported 94% of human cases. Rather than direct mutation, p53 is held inactive through interaction with inhibitory proteins. Here, we examine the expression of the two primary inhibitors of p53, MDM2 and MDM4, in genomic databases and biopsy specimens. We find that MDM4 is frequently overexpressed. Moreover, changes in splicing of MDM4 occur frequently and early in melanomagenesis. These changes in splicing must be considered in the design of therapeutic inhibitors of the MDM2/4 proteins for melanoma.
Value of Follow-Up N-Terminal Probrain Natriuretic Peptide (NT-proBNP) after a Modified Fontan Procedure
Authors: Li Jianbin , Ma Li , Zou Minghui , Li Wenlei , Chen Xinxin , Cui Yanqin , Hu Xiaoyan
Published: October 2021

Objective. To assess the value of N-terminal probrain natriuretic peptide (NT-proBNP) in short-term and long-term follow-up after a modified Fontan procedure. Methods. We retrospectively enrolled children who had undergone a modified Fontan procedure in the Heart Center of Guangzhou Women and Children’s Medical Center from January 2014 to September 2020 and collected data on NT-proBNP values before bidirectional Glenn procedure, before Fontan procedure, and on 1, 3, 7, 30, 90, and 180 days and 1, 2, 3, 4, 5, and 6 year after Fontan procedure. The relationship between changes in NT-proBNP levels and the outcomes in children was analyzed. Results. A total of 108 children (78 boys and 30 girls, mean age: 54.62 ± 29.38 weeks) were included in the analysis. According to one-way analysis of variance, the left ventricular type and biventricular type of single ventricle physiology showed shorter duration on cardiopulmonary bypass during the operation and lower levels of NT-proBNP after the operation than the right ventricular type and univentricular type physiology. Conclusion. NT-proBNP is a good indicator for mid and long-term follow-up after a modified Fontan procedure. The left ventricular type and biventricular type of single ventricle physiology show better mid and long-term benefits from the modified Fontan procedure than the right ventricular type and univentricular type physiology.
RTJTN: Relational Triplet Joint Tagging Network for Joint Entity and Relation Extraction
Authors: Yang Zhenyu , Wang Lei , Ma Bo , Yang Yating , Dong Rui , Wang Zhen
Published: October 2021

Extracting entities and relations from unstructured sentences is one of the most concerned tasks in the field of natural language processing. However, most existing works process entity and relation information in a certain order and suffer from the error iteration. In this paper, we introduce a relational triplet joint tagging network (RTJTN), which is divided into joint entities and relations tagging layer and relational triplet judgment layer. In the joint tagging layer, instead of extracting entity and relation separately, we propose a tagging method that allows the model to simultaneously extract entities and relations in unstructured sentences to prevent the error iteration; and, in order to solve the relation overlapping problem, we propose a relational triplet judgment network to judge the correct triples among the group of triples with the same relation in a sentence. In the experiment, we evaluate our network on the English public dataset NYT and the Chinese public datasets DuIE 2.0 and CMED. The F1 score of our model is improved by 1.1, 6.0, and 5.1 compared to the best baseline model on NYT, DuIE 2.0, and CMED datasets, respectively. In‐depth analysis of the model’s performance on overlapping problems and sentence complexity problems shows that our model has different gains in all cases.
Product Antimagic Labeling of Caterpillars
Authors: Wang Shengze , Gao Yuping
Published: October 2021

Let

G

be a graph with

m

edges. A product antimagic labeling of

G

is a bijection from the edge set

E

G

to the set

1,2
,
…
,
m

such that the vertex-products are pairwise distinct, where the vertex-product of a vertex

v

is the product of labels on the incident edges of

v

. A graph is called product antimagic if it admits a product antimagic labeling. In this paper, we will show that caterpillars with at least three edges are product antimagic by an

O

m
 
 
log
 
 
m

algorithm.
A Case of Trichinellosis in a 14-Year-Old Male Child at Hawassa University Comprehensive Specialized Hospital, Hawassa, Sidama, Ethiopia
Authors: Melese Abebe , Mohammed Musa , Ketema Worku , Toma Alemayehu
Published: October 2021

Background. Trichinellosis develops after ingestion of Trichinella cysts in pork meat. It is one of the most important parasitic human pathogens in the world. It is, however, underreported in part because none of the clinical manifestations are pathognomonic. The primary mode of transmission is ingestion of raw meat. Among the symptoms are muscle pain, swelling, and myopathy. High-grade fever and other systemic symptoms are not unusual. The hallmarks are ophthalmic and musculoskeletal manifestations, particularly conjunctival haemorrhage with periorbital edema and subungual splinter haemorrhage. Although the majority of infections are mild and asymptomatic, severe infections can result in enteritis, periorbital edema, and myositis. Presentation of the Case. A 14-year-old male patient from Oromia Region, Arsi Zone, West Arsi Zone, Bishan Guracha area, which is almost completely encircled by mountains, presented with a complaint of worsening easy fatigability and asymmetric right thigh enlargement lasting one month. The pertinent physical examinations on presentation were puffy face and eyes, and there was a 4 cm by 5 cm mass on the right lateral thigh with no overlying skin colour change, on-tender, and no discharge. Eosinophilia of 14% was noticed on the complete blood count. The definitive diagnosis of trichinellosis was made by muscle biopsy. He was then managed with albendazole and prednisolone and improved. Conclusion. Patients with periorbital edema, myositis, or eosinophilia should be evaluated for trichinellosis. Individuals who have these symptoms and a history of eating pork meat should be suspected of having trichinellosis. Before eating raw pork meat, it is recommended that it be cooked properly.
Automatic Decision Algorithm of Interpretation Power in Criminal Justice Based on Data Activity Consultant
Authors: Yang Xiaolong
Published: October 2021

In order to solve the problems existing in the current decision algorithm, such as poor data processing performance, low decision accuracy, and long decision time, an automatic decision algorithm of criminal justice interpretation right based on data activity consultant was designed. According to the requirements of reasonable design consultant system data activity and demanded data activity consultants provide data processing requirements and scope. Use the Scrapy web crawler framework to crawl data related to criminal justice interpretation and criminal law provisions from related websites, and clear and extract the collected data to realize data query. Based on the obtained data, the feature array of criminal law is designed, and the decision of criminal judicial interpretation right is made. The C4.5 decision tree algorithm is used to predict the correct rate of decision. The decision of criminal judicial interpretation right is adjusted constantly according to the prediction results to achieve the goal of the automatic decision of criminal judicial interpretation right. Experimental results show that the algorithm has superior data processing performance, high decision accuracy, and short decision time, which verifies the effectiveness of the algorithm.
Research and Application of Film and Television Literature Recommendation Based on Secure Internet of Things and Machine Learning
Authors: Zhou Jieqiong , Wei Zhenhua , Peng Bin , Chi Fangchun
Published: October 2021

Film and television literature recommendation is an AI algorithm that recommends related content according to user preferences and records. The wide application in various APPs and websites provides users with great convenience. This article aims to study the Internet of Things and machine learning technology, combining deep learning, reinforcement learning, and recommendation algorithms, to achieve accurate recommendation of film and television literature. This paper proposes to use the ConvMF-KNN recommendation model to verify and analyze the four models of PMF, ConvM, ConvMF-word2vec, and ConvMF-KNN, respectively, on public datasets. Using the path information between vertices in bipartite graph and considering the degree of vertices, the similarity between items is calculated, and the neighbor item set of items is obtained. The experimental results show that the ConvMF-KNN model combined with the KNN idea effectively improves the recommendation accuracy. Compared with the accuracy of the PMF model on the MovieLens 100 k, MovieLens 1 M, and AIV datasets, the accuracy of the ConvMF model on the above three datasets is 5.26%, 6.31%, and 26.71%, respectively, an increase of 2.26%, 1.22%, and 7.96%. This model is of great significance.
Participant and Strategy Selection of Health QR Code Product Experience Design during the COVID-19 Pandemic in China: The Information Security Perspective
Authors: Su Zishun , Zou Qiaoling , Wu Xinying , Ye Junnan , Cheng Jianxin
Published: October 2021

Health QR code is an Internet product designed and developed by China to combat the COVID-19 pandemic. In order to build a public health and epidemic prevention barrier, the Chinese government’s health QR code product is a useful attempt to deal with epidemic prevention and control and social governance in the way of “Internet plus big data”. In the process of health QR code product design and development, we conduct a security analysis of information data and employ project management, product design, development and testing, online, and operational product experience design methods. User requirements and product definitions for the health QR code include management, design, development, and testing. The main participants of health QR code product experience design are divided into product manager, design and development team, and users. The relationships among the product manager, the design and development team, and users are established using the evolutionary game method. It is found that the cost of information security has an important influence on the choice of the user policy. Product managers, driven by benefits and values, may ignore the importance of information security when choosing the strategy for health QR code products, which will affect users' enthusiasm to use them to some extent and limit their use scenarios and application scope. Therefore, in order to achieve healthy user interaction and sustainable experience design of health QR code products, it is necessary to strengthen data security protection and reduce the cost of information interaction and sharing. Furthermore, on the basis of enhancing user viscosity and improving the usability of health QR code products, our research results show the further need for demand mining and version upgrading of health QR code products.
Deformation and Mechanical Properties of a Constant‐Friction‐Force Energy‐Absorbing Bolt
Authors: Song Tao , Li Tianbin , Meng Lubo , Ma Chunchi , Li Chaofei , Peng Feng
Published: October 2021

The conventional bolts used in surrounding rock tunnels with large deformation often fail. As a solution to this problem, we developed an extensible bolt with energy‐absorbing and constant‐friction‐force (EACF) characteristics. The EACF bolt mainly comprises a damping device, a hollow threaded bolt, a tightening nut, and a face plate. To reveal its working mechanism, the bolt was tested in terms of its friction, displacement, and energy absorption through a modified tensile test device in a laboratory. The static pull‐out test results showed that the axial force‐displacement curve of the bolt can be mainly divided into three stages: a conical extrusion stage, an elongation stage, and an elastic failure stage. The EACF bolts exhibited stable energy absorption behaviors when subjected to static loading. The maximum constant friction force could be adjusted by increasing the size and diameter of the straight section of the damping block, and the maximum elongation could be adjusted by increasing the length of the damping cylinder. When the properties of the bolt materials are kept constant, increasing the diameter of the damping block can help achieve a high constant resistance. The proposed EACF bolt has reliable deformation and energy‐absorption properties, which ensure its stability when employed in tunnels under the combined action of support and surrounding rocks.
Hybrid Approach for Resource Allocation in Cloud Infrastructure Using Random Forest and Genetic Algorithm
Authors: S Madhusudhan H , Kumar T Satish , Mustapha S.M.F D Syed , Gupta Punit , Tripathi Rajan Prasad
Published: October 2021

In cloud computing, the virtualization technique is a significant technology to optimize the power consumption of the cloud data center. In this generation, most of the services are moving to the cloud resulting in increased load on data centers. As a result, the size of the data center grows and hence there is more energy consumption. To resolve this issue, an efficient optimization algorithm is required for resource allocation. In this work, a hybrid approach for virtual machine allocation based on genetic algorithm (GA) and the random forest (RF) is proposed which belongs to a class of supervised machine learning techniques. The aim of the work is to minimize power consumption while maintaining better load balance among available resources and maximizing resource utilization. The proposed model used a genetic algorithm to generate a training dataset for the random forest model and further get a trained model. The real-time workload traces from PlanetLab are used to evaluate the approach. The results showed that the proposed GA-RF model improves energy consumption, execution time, and resource utilization of the data center and hosts as compared to the existing models. The work used power consumption, execution time, resource utilization, average start time, and average finish time as performance metrics.
Computer Simulation of Water Flow Animation Based on Two-Dimensional Navier-Stokes Equations
Authors: Cao Rushi , Cao Ruyun
Published: October 2021

Simulation of water flow animation is a significant and challenging subject in computer graphics. With the continuous development of computational fluid dynamics and computer graphics, many more effective simulation methods have been developed, and fluid animation simulation has developed rapidly. In order to obtain realistic flow animation, one of the key aspects is to simulate flow motion. Based on the two-dimensional Navier-Stokes equations, a mathematical model is established to solve the boundary conditions required by the physical flow field of water. The coordinate transformation formula is introduced to transform the irregular physical area into a regular square calculation area, and then, the specific expressions of the liberalized Navier-Stokes equation, continuity equation, pressure Poisson equation, and dimensionless boundary conditions are given. Using animation software to sequence graphics and images of all kinds of control and direct operation of the relevant instructions, through the computer technology to simulate the flow of animation, based on the stability of fluid simulation method and simulation efficiency, so as to make realistic flow animation. The results show that FluidsNet has considerable performance in accelerating large scene animation simulation on the basis of ensuring the rationality of prediction, and the motion of water wave is realistic. The application of computer successfully simulates water flow.
In Vitro Antagonistic Effect of Lactic Acid Bacteria Isolated from Fermented Beverage and Finfish on Pathogenic and Foodborne Pathogenic Microorganism in Ethiopia
Authors: Dejene Fitsum , Regasa Dadi Belayneh , Tadesse Dagimawie
Published: October 2021

Background. Lactic acid bacteria from fermented foods and fish can antagonistically inhibit the growth of foodborne pathogenic organism in fermented food and they stimulate the immune response to protect the fish from certain kinds of infections. The aim of this study was to evaluate the in vitro antagonistic activities of lactic acid bacteria isolated from fermented beverage (Borde) and finfish on foodborne pathogenic microorganisms. Methods. Laboratory-based experimental study was conducted from May 1 to Sep 1, 2020. Total sample numbers were 60 samples of fermented beverage (Borde) and 20 of finfish which were collected from different households and Chamo Lake (Arba Minch, Ethiopia). Each sample was firstly homogenized and serial dilution was prepared and spread on MRS agar plates in order to isolate pure culture. Different biochemical tests were performed to identify isolated bacteria. Then, cell-free supernatant (CFS) was prepared from MRS culture and used in an antimicrobial assay that was performed by agar diffusion method. The effects of pH, temperature, and enzymes on antimicrobial activity were evaluated in the same test. Simultaneously, the effects of lactic acid bacteria on aflatoxin production and on the permeability of the membrane were also evaluated. Data were analyzed using one-way ANOVA and Tukey post hoc analysis was performed by SPSS 25 statistical software. Result. A total of 40 lactic acid bacteria were isolated; among them, 4 lactic acid bacteria, belonging to the genera Enterococcus, Leuconostoc, and Weisellia from fermented beverage and Pediococcus from fish, were screened for antimicrobial activity. The cell-free supernatant of those four isolates exhibited a significant (p<0.05) antibacterial effect against tested pathogens and foodborne pathogenic bacteria. In addition, CFS showed antifungal and antiaflatoxigenic activities. The antimicrobial compounds synthesized by these isolates were sensitive to some proteolytic enzymes, and they were proved to be stable at high temperatures. It maintained/retained antimicrobial activity in a wide range of pH 2.0–10. Enterococcal CFS exhibited antibacterial activity against S. aureus on membrane permeability, as confirmed by the increase in absorbance value between 0.075 and 0.24 at OD280-nm and between 0.68 and 1.2 at OD260-nm. Conclusion. Cell-free supernatant produced by isolated lactic acid bacteria showed antimicrobial activity against a wide range of Gram-positive and Gram-negative foodborne bacteria, suggesting its potential application as a natural antimicrobial agent in tackling the rising drug resistance against foodborne pathogens.
Migration of the Industrial Wastewater in Fractured Rock Masses Based on the Thermal-Hydraulic-Mechanical Coupled Model
Authors: Gao Yanan , Guo Peng , Zhang Zetian , Li Minghui , Gao Feng
Published: October 2021

Industrial wastewater may have a long-time effect on the environment and human life as it goes underground and causes serious pollution continuously. To have a well understanding of the migration of such wastewater is a basic task for industrial wastewater treatment as well as industrial design. To study the migration mechanism of industrial wastewater in rock formations, the governing equations such as mechanics, seepage, heat, and mass transfer are reviewed, referenced, and proposed. The thermal (T)-hydraulic (H)-mechanical (M) coupled model of the multimedia of matrix-fault and matrix-fracture-fault is established. The influence of the fault and the fractures on the pressure distribution and contaminant migration is analyzed. The influence of fault length, width, dip angle, permeability, and temperature of wastewater on contaminant migration is parametrically studied. The following results can be obtained. (1) The fracture quantitively affects the concentration distribution, while the fault dominates the concentration distribution and contaminant migration. (2) The migration of the contaminants can be geometrically divided into 3 zones along the direction of the fault: the saturation zone, the rapid diffusion zone, and the concentration decrease zone. (3) There is a peak of the concentration along the bottom of the model. The position of the peak is the projection of the endpoint of the fault. (4) The fault length has the most significant effect on contaminant accumulation. The temperature of the wastewater has the minimum effect on the contaminant accumulation. (5) The accumulation of concentrations can be divided into 2 stages, the slow growth stage (before 20 years) and the rapid growth stage (after 20 years). The main channel of contaminant migration in the slow growth stage is a fault. During the rapid growth stage, the contaminants penetrate through the rock matrix as well as the fault.
Urethral Tissue Reconstruction Using the Acellular Dermal Matrix Patch Modified with Collagen‐Binding VEGF in Beagle Urethral Injury Models
Authors: Wang Yanni , Wang Guannan , Hou Xianglin , Zhao Yannan , Chen Bing , Dai Jianwu , Sun Ning
Published: October 2021

Objectives. Urethral tissue reconstruction for hypospadias is challenging for urologists. In this study, bovine acellular dermal matrix (ADM) patch loading with collagen‐binding vascular endothelial growth factor (CBD‐VEGF) was used to repair the urethral injury in beagles. Methods. The safety and effectiveness of the scaffold implantation were carefully evaluated by comparing among the urethral injury control group, ADM implantation group, and ADM modified with CBD‐VEGF implantation group during 6 months. Urodynamic examination, urethral angiography, and pathological examination were performed to evaluate the recovery of urethral tissue. Results. Stricture, urethral diverticulum, and increased urethral closure pressure were observed in the control group. Fistula was observed in one animal in the ADM group. By contrast, no related complications or other adverse situations were observed in animals treated with ADM patch modified with CBD‐VEGF. The average urethra diameter was significantly smaller in the control animals than in scaffold implantation groups. Pathological examination revealed more distribution of proliferative blood vessels in the animals treated with ADM modified with CBD‐VEGF. Conclusions. Overall, ADM patches modified with CBD‐VEGF demonstrated an optimized tissue repair performance in a way to increase tissue angiogenesis and maintain urethral function without inducing severe inflammation and scar formation.
Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen‐Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells
Authors: Burke Rebecca , Chu Chun , Zhou Guo-Dong , Putluri Vasanta , Putluri Nagireddy , Stading Rachel E. , Couroucli Xanthi , Lingappan Krithika , Moorthy Bhagavatula
Published: October 2021

Supplemental oxygen administration is frequently used in premature infants and adults with pulmonary insufficiency. NADPH quinone oxidoreductase (NQO1) protects cells from oxidative injury by decreasing reactive oxygen species (ROS). In this investigation, we tested the hypothesis that overexpression of NQO1 in BEAS‐2B cells will mitigate cell injury and oxidative DNA damage caused by hyperoxia and that A‐1221C single nucleotide polymorphism (SNP) in the NQO1 promoter would display altered susceptibility to hyperoxia‐mediated toxicity. Using stable transfected BEAS‐2B cells, we demonstrated that hyperoxia decreased cell viability in control cells (Ctr), but this effect was differentially mitigated in cells overexpressing NQO1 under the regulation of the CMV viral promoter, the wild‐type NQO1 promoter (NQO1-NQO1), or the NQO1 promoter carrying the SNP. Interestingly, hyperoxia decreased the formation of bulky oxidative DNA adducts or 8‐hydroxy‐2 ′‐deoxyguanosine (8‐OHdG) in Ctr cells. qPCR studies showed that mRNA levels of CYP1A1 and NQO1 were inversely related to DNA adduct formation, suggesting the protective role of these enzymes against oxidative DNA injury. In SiRNA experiments entailing the NQO1-NQO1 promoter, hyperoxia caused decreased cell viability, and this effect was potentiated in cells treated with CYP1A1 siRNA. We also found that hyperoxia caused a marked induction of DNA repair genes DDB2 and XPC in Ctr cells, supporting the idea that hyperoxia in part caused attenuation of bulky oxidative DNA lesions by enhancing nucleotide excision repair (NER) pathways. In summary, our data support a protective role for human NQO1 against oxygen‐mediated toxicity and oxidative DNA lesions in human pulmonary cells, and protection against toxicity was partially lost in SNP cells. Moreover, we also demonstrate a novel protective role for CYP1A1 in the attenuation of oxidative cells and DNA injury. Future studies on the mechanisms of attenuation of oxidative injury by NQO1 should help in developing novel approaches for the prevention/treatment of ARDS in humans.
A Review on Computational Fluid Dynamics Applications in the Design and Optimization of Crossflow Hydro Turbines
Authors: Mrope Hamisi Ally , Chande Jande Yusufu Abeid , Kivevele Thomas T.
Published: October 2021

In recent years, advances in using computational fluid dynamics (CFD) software have greatly increased due to its great potential to save time in the design process compared to experimental testing for data acquisition. Additionally, in real-life tests, a limited number of quantities are measured at a time, while in a CFD analysis all desired quantities can be measured at once, and with a high resolution in space and time. This article reviews the advances made regarding CFD modeling and simulation for the design and optimization of crossflow hydro turbines (CFTs). The performance of these turbines depends on various parameters like the number of blades, tip speed ratio, type of airfoil, blade pitch, chord length and twist, and its distribution along the blade span. Technical aspects of the model design, which include boundary conditions, solution of the governing equations of the water flow through CFTS, and the assumptions made during the simulations are thoroughly described. From the review, a clear idea on the suitability of the accuracy CFD applications in the design and optimization of crossflow hydro turbines has been provided. Therefore, this gives an insight that CFD is a useful and effective tool suitable for the design and optimization of CFTs.
The Dynamic Movement of Disaster Management Systems Based on Vehicle Networks and Applied on the Healthcare System
Authors: Alazzam Malik Bader , Alassery Fawaz
Published: October 2021

In order to save human life and assets, the emergency management system (DMS) requires roving rescue teams to respond promptly and effectively. Installation and restoration of appropriate communication infrastructure are important for reducing the effect of disasters and enabling and coordinating information flow among relief teams working in the region. This paper describes a data collection system based on vehicular cloud network services that incorporates the advantages of both architectures of vehicular ad hoc networks (VANETs) with the cloud to establish vehicular cloud networks (VCNs). Vehicles in the current plan perform tasks like monitoring the environment, gathering data, and transmitting data to the control center depending on their positions and instructions. To build a disaster management system, the proposed system uses hybrid wireless networking, which includes both a central system and ad hoc networks. The implementation results show that the suggested system is more dependable and efficient; even light density is improved in terms of reachability with few hops. Furthermore, as compared to the existing system, the suggested system has a lower end-to-end delay and a higher packet delivery ratio.
Protein Phosphatase PP2C Identification in Entamoeba spp
Authors: Navarrete-Mena Abril , Pacheco-Yépez Judith , Hernández-Ramírez Verónica Ivonne , Escalona-Montaño Alma Reyna , Gómez-Sandoval Jenny Nancy , Néquiz-Avendaño Mario , Chávez-Munguía Bibiana , Tesoro-Cruz Emiliano , Talamás-Rohana Patricia , Aguirre-García María Magdalena
Published: October 2021

Entamoeba histolytica is the causative agent of amoebiasis, and Entamoeba dispar is its noninvasive morphological twin. Entamoeba invadens is a reptilian parasite. In the present study, Western blot, phosphatase activity, immunofluorescence, and bioinformatic analyses were used to identify PP2C phosphatases of E. histolytica, E. dispar, and E. invadens. PP2C was identified in trophozoites of all Entamoeba species and cysts of E. invadens. Immunoblotting using a Leishmania mexicana anti‐PP2C antibody recognized a 45.2 kDa PP2C in all species. In E. histolytica and E. invadens, a high molecular weight element PP2C at 75 kDa was recognized, mainly in cysts of E. invadens. Immunofluorescence demonstrated the presence of PP2C in membrane and vesicular structures in the cytosol of all species analyzed. The ~75 kDa PP2C of Entamoeba spp. shows the conserved domain characteristic of phosphatase enzymes (according to in silico analysis). Possible PP2C participation in the encystation process was discussed.
Automatic Detection of Grammatical Errors in English Verbs Based on RNN Algorithm: Auxiliary Objectives for Neural Error Detection Models
Authors: He Yizhou
Published: October 2021

With the rapid development of neural network technology, we have widely used this technology in various fields. In the field of language translation, the research on automatic detection technology of English verb grammatical errors is in a hot stage. The traditional manual detection cannot be applied to the current environment. Therefore, this paper proposes an automatic detection technology of English verb grammatical errors based on recurrent neural network (RNN) algorithm to solve this problem. Firstly, the accuracy and feedback speed of traditional manual detection and recurrent neural network RNN algorithm are compared. Secondly, a detection model which can be calculated according to grammatical order combined with context is designed. Finally, when the output verb result is inconsistent with the original text, it can automatically mark the error detection effect. The experimental results show that the algorithm model studied in this paper can effectively improve the detection accuracy and feedback efficiency and is more applicable and effective than the traditional manual detection method.
Effects of pH and Electrolytes on Castor Oil Emulsions with Various Stabilisers Using Khaya senegalensis Gum as an Emulsifier
Authors: Kuevi Deryl Nii Okantey , Kuntworbe Noble , Ayertey Enoch
Published: October 2021

Dispersed systems such as emulsions are easily destabilised during processing and storage since they are thermodynamically unstable systems. It is for this reason emulsifiers/stabilisers are frequently employed in pharmaceutical emulsion formulations to increase their short- and long-term kinetic stability. This current study seeks to investigate the potential emulsifying property of gums obtained from Khaya senegalensis (family: Meliaceae) trees. Gums were collected, authenticated, oven-dried, milled, filtered, and purified using 96% ethanol. The microbial quality of the gum was assessed following the BP (2013) specifications. The purified gum was free from some selected pathogenic microorganisms, rendering the gum safe for consumption. The emulsifying property was investigated by formulating emulsions using castor oil and employing the dry gum method. The ratios of oil-to-water-to-gum for the formulation of a stable emulsion were determined. The stability of the emulsion was evaluated, and an effort was made to improve the stability by incorporating Tween 80, hydroxypropyl methylcellulose, and xanthan gum. From the results, it can be inferred that Tween 80 (0.5%) was able to stabilise the emulsion. Addition of xanthan gum worsened the creaming. The effects of pH (4.0, 5.5, 7.2, 9.0, and 11.0) and electrolytes (0.1 M of NaCl, KCl, and CaCl2) on the physical stability of oil-in-water emulsions were studied during 12 weeks of storage. Percentage creaming volume and whether there was phase inversion were the criteria used as the evaluation parameter. From the percentage creaming volume data, emulsions formulated with both gums showed the lowest creaming volumes at pH of 7.2, followed by the acidic regions (pH 4.0, 5.5), with the basic regions (pH 9.0, 11.0) recording the highest creaming volumes. The effects of the various electrolytes at a constant concentration of 0.1 M on the o/w emulsions were found in this order NaCl < KCl < CaCl2. This study proves that Khaya senegalensis gum can successfully be employed as an emulsifying agent in pharmaceutical formulations.
Early Physical Linear Growth of Small-for-Gestational-Age Infants Based on Computer Analysis Method
Authors: Ruixiang Li , Mingrong Yin , Li Cui , Rongxiu Zheng
Published: October 2021

This article proposes that machine learning can break through the technical limitations of the linear growth test for the early physique of infants smaller than gestational age and can accurately calculate and predict the consequences of the disease. For testing the linear growth of the early physique of infants smaller than gestational age, the data collection and judgment are carried out according to the computer analysis method. Experimental results show that 47.3% of infants younger than gestational age may have suffocation. The experimental subjects designed in this study are small-for-gestational-age infants who were hospitalized in the neonatal intensive care unit from January 2020 to January 2021. According to the relationship between gestational age and birth weight, the survey subjects were divided into two groups: early group and late group. Male and female small-for-gestational-age infants accounted for 68% and 32%, respectively. Among them, the proportion of early gestational age was the most, with more boys than girls, and sick singleton was more than twins. In the early group, the incidence was 52.1% for neonatal asphyxia, 22.5% for feeding intolerance, 14.8% for intracranial hemorrhage, 6.3% for scleredema, 24.7% for neonatal hyperbilirubinemia, 24.6% for hypoglycemia, 1.1% for apnea, and 3.2% for respiratory distress syndrome. Infants develop differently at different stages of corrected gestational age. The incidence of low body weight (6%) after correction for 3 months was significantly reduced compared with correction for gestational age, and the difference was statistically significant (

P

 < 0.05). The nutrient absorption of infants younger than gestational age can promote physical catch-up growth, physical development, and neurodevelopment. Therefore, the physical growth of infants younger than gestational age requires supplementation that focuses on nutrition.
An Efficient Mathematical Approach for the Fraction Order Differentiation Based on Future Applications of Chaotic Parameter
Authors: Bary Ghulam , Ahmed Waqar , Sajid Muhammad , Ahmad Riaz , Saleem Khan Muhammad Farooq , Fayz-Al-Asad Md , Hamadneh Nawaf N. , Khan Ilyas
Published: October 2021

Normalized chaotic parameters examine the characterization of the particle production fluids produced at unusual energies and investigate a remarkable behavior in quantum measurement. The analogous characterization can be analyzed to probe the chaotic systems of boson particles creating sources of extraordinary energy. We observe that the bosons appear to be the appropriate aspirants of chaos fractions, and the normalized chaotic parameters evaluate the presence of such conglomerate phases significantly. The core point of this manuscript is that we calculate and examine the normalized chaotic parameters by differential equations to analyze the characteristics of the chaotic systems and their applications in thermal as well as in mechanical engineering. With such an efficient and distinctive approach, we perceive significant consequences for the correlator at higher temperature regimes.