bluuebunny/crossref_metadata_2025 huggingface dataset:
The Relationship between Plasminogen Activator Inhibitors and the Severity of COVID-19
Authors: Troeman Kyna , Aman Adi Koesoema , Nasution Malayana Rahmita
Published: October 2024

The fibrinolysis process is assisted by plasminogen activators and inhibitors by converting plasminogen into plasmin, which later will promote the fibrinolysis process. Incomplete fibrinolysis increases the risk of thrombosis in patients with COVID-19. Plasminogen Activator Inhibitor (PAI-1) plays an important role as acute phase reactants to be used as a marker to assess the prognosis and mortality of COVID-19 patients. This study aimed to elaborate on whether fibrinolysis shutdown occurs in COVID-19 patients using PAI-1 as a marker of fibrinolysis. This was a cross-sectional analytical study from November 2022 to May 2023. This research consisted of a total of 39 patients with COVID-19, hospitalized at Haji Adam Malik General Hospital, Medan. PAI-test in COVID-19 patients was carried out with the ELISA method using Chemwell Analyzer. The severity of COVID-19 measured by clinical examination was divided into moderate, severe, and critical. The association between the two variables was subjected to a comparative test followed by a correlation test to explore the association between the two variables with an independent T-test. In this study, the median PAI-1 level was 1.77 ng/mL (0.71–11.49 ng/mL). The highest PAI-1 levels were observed in the critical severity group, followed by the severe and moderate group of 8.54 ng/mL (5.76–10.84), 2.45 ng/mL (0.71–11.49), and 1.29 ng/mL (0.73–3.77), respectively. There was a significant relationship between PAI-1 levels and the severity of COVID-19 patients (p=0.003). PAI-1 cut-off value of 1.89 ng/mL may predict the degree of COVID-19 severity with sensitivity of 88.9%, specificity of 90.5%, and accuracy of 89.7%. This study classified the severity of COVID-19 into two categories, which are moderate (n=21) and severe-critical (n=18) to obtain the AUC value of PAI-1. PAI-1 can be used to predict the severity of COVID-19 disease with a moderate level (AUC >70–80%). This phenomenon can be secondary to enhanced platelet aggregation, inflammation micro thrombosis, and impaired fibrinolysis. Fibrinolysis disorders lead to a fibrin buildup and increased levels of PAI-1 in the circulation.
Human agility management in Thai SMEs: A catalyst for enhancing employee value proposition
Authors: Piriyakul Intaka , Sirijai Benjamas , Piriyakul Rapepun , Chiranunthadej Noraphol
Published: October 2024

This study investigates the application of Operational Agility Management in Thai SMEs, examining its impact on Employee Dynamic Capability and the resulting Employee Value Proposition. Using a quantitative approach with a questionnaire survey targeted at Thai SME executives, the research analyzes the relationships between “Value of Work”, “Goal Orientation”, and “Network Communication” as independent variables, “Employee Dynamic Capability” as a mediating variable, and “Employee Value Proposition” as the dependent variable. The findings reveal that Thai Small and Medium-sized Enterprises (SMEs) struggle particularly with “Network Communication” in enhancing their “Employee Value Proposition”, primarily due to their predominant hierarchical command structure. This challenge highlights the need for Thai SMEs to reassess their organizational structures and communication practices to improve employee dynamic capabilities and overall employee value proposition. The study provides novel insights into the application of Operational Agility Management in Thai SMEs, bridging the gap between high-performance management theories and the practical realities faced by SMEs in unpredictable business environments, thus offering a unique perspective on cultivating employee dynamic capabilities in this setting.
Modelling tourists’ travel intention: Role of tourism destination image, perceived value and situational involvement
Authors: Li Yongyi , Jiang Songyu
Published: October 2024

Promoting travelling intention within social media is significant for stakeholders to grasp a new tourism market and cultivate a new model for development of tourism industry. This study aims to understand path of destination image affecting travelling intention, and to investigate the mediation role of perceived value, furthermore, to uncover the role of moderator of situational involvement. This paper conducts a survey on tourists visiting Guilin, collecting 435 questionnaires, and uses the structural equation modeling method to explore how the image of the tourism destination affects tourists’ willingness to travel. The research results indicate that cognitive image, emotional image, and projected image all have a significant positive impact on perceived value, perceived value as a significant mediator to bridge the relationship among the destination image and tourists’ travel intention. Furthermore, situational involvement plays a negative moderating role in the mediating effect of emotional value. This study endeavor will serve to enrich the understanding of perceived value theory, destination image theory, and tourism consumer behavior theory. It will also provide theoretical foundations and policy recommendations for guiding tourism consumer behavior, analyzing destination image perception, and destination marketing.
The impact of changes in macroeconomic factors on banks’ lending behaviour
Authors: Sangweni Mayibongwe , Takawira Oliver
Published: October 2024

Loans are a critical transmission channel for commercial banks as well as an important revenue source. Macroeconomic factors are not within the control of commercial banks, however, select factors are observed to have a direct impact on lending behaviour in studies around the world. This study examined the relationship between macroeconomic variables and the lending behaviour of banks in South Africa for the period ranging from 2001 to 2022. Quarterly time series data was employed using the Autoregressive Distributed Lag Model (ARDL). The empirical results of the paper revealed that there is a long-run relationship between the repurchase rate (repo rate), inflation, the real effective exchange rate (REER) and lending behaviour in South Africa. The REER and inflation were both found to have a positive relationship, whilst the repo rate had a negative relationship. In addition, Gross Domestic Product (GDP), the activity rate and sovereign credit rating (SCR) changes returned insignificant results. Overall, these findings show that select macroeconomic factors do influence lending behaviour in South Africa. Furthermore, the results suggest that monetary policy decisions have a direct influential effect on lending and the South African Reserve Bank (SARB) has implemented their policies effectively.
Digital transformation and building e-courts to meet the requirements of judicial reform in Vietnam
Authors: Duong Quynh Hoa
Published: October 2024

Currently, the rapid development of information technology has brought lots of opportunities for improving the efficiency of national governance activities and the implementation of justice in the world. The Fourth Industrial Revolution and the continuous development of digital technology have been profoundly changing the operation of the courts and providing opportunities for nations to transform from the traditional court model to the electronic court one. Building an e-court has become a global trend in order to respond to the COVID-19 pandemic and overcome court delays in resolving disputes. In that context, Vietnam has also advocated promoting the application of information technology, making the most of opportunities that are brought by the technological revolution so as to build e-courts, one of the important tasks of the Judicial Reform Strategy. From 2019 up to now, Vietnam has made efforts to strengthen judicial reform and build e-courts, however, the results are still quite modest. By qualitative research method, this article examines the achievements Vietnam has achieved as well as the limitations when the court system transforms to the e-court model, thereby making some recommendations to successfully build an e-court in Vietnam in order to meet the requirements of judicial reform.
Prohibition of public employees from practicing commercial activities in the legislation of the United Arab Emirates and the French Republic: A comparative study
Authors: Alnujaifi Mustafa , Alheety Noaman Atallah , Atallah Mohammad Noaman , Dganni Khalid Mohamed , Obeidat Muayad Ahmad , AlFalahi Buti Obaid Saeed , Lamdjad Imane
Published: October 2024

Practicing commercial activities as a public employee is a major negative phenomenon that affects the public interest, institutions, and employers, and affects economic development. Both the economy and society as a whole have significant effects on countries throughout all sectors. The study aimed to identify legislation restricting commercial activity by public sector workers in the United Arab Emirates and France. This research was based on the comparative descriptive approach between UAE legislation and French comparative legislation in the field of prohibiting public servants from engaging in business activities. The research concluded with a variety of findings, the most notable of which is the fact that the UAE legislature was flexible in dealing with this issue, making it simpler for employees to conduct businesses by reducing the load of life troubles on public employees. The study recommended the Establishing procedures, systems and rules for reporting to the competent authorities by public employees about acts of practicing commercial activities, when these acts come to their knowledge during the performance of their duties.
Petrology, mineral chemistry and geochemistry of chloritite associated with Neoproterozoic ophiolitic ultramaficsin the Eastern Desert of Egypt, Arabian-Nubian Shield
Authors: Abuamarah Bassam A. , Seddik Amany M.A. , Azer Mokhles K. , Bartoli Omar , Darwish Mahmoud H.
Published: October 2024

This study presents for the first time, the field observations, petrography, mineral chemistry and geochemistry of chloritite hosted in the Al-Barramiya Neoproterozoic ophiolite of the Eastern Desert of Egypt, Arabian-Nubian Shield (ANS). The Al-Barramiya ophiolite is one of the most important ophiolitic sequences exposed in the ANS. It is affected by different types of alterations including carbonatization, listvenitization, chloritization and rodingitization. The Al-Barramiya chloritite occurs as thin layers associated with highly serpentinized peridotite. It is a fine-grained rock entirely composed of chlorite (85–95 vol.%) with minor talc and accessory minerals (epidote, rutile, titanite, corundum and opaque minerals). The chlorite minerals in the chloritite are represented mainly by diabantite, while those in the serpentinites include ripidolite. Depending on the chemical composition of the chlorites, the chlorite in chloritite formed at temperatures ranging between 200 and 250°C, which are lower than those of the disseminated chlorite in the serpentinite (310–345oC), indicating their formation in different hydrothermal stages. The chloritite samples are rich in total REE contents (17.9–27.3 ppm) compared with the associated serpentinites (0.69–0.87 ppm). They are characterized by slightly depleted LREE relative to HREE [(La/Lu)n = 0.8–0.9], with a moderately negative Eu-anomaly [(Eu/Eu*)n = 0.4–0.5]. The negative Eu-anomalies are derived from chloritization fluids or reflect the presence of talc in the chloritite. Based on field work, petrography, mineralogical and geochemical data, the studied chloritite has been interpreted as being derived from the associated serpentinized ultramafics by hydrothermal alterations. This is supported by an enrichment of chloritite in compatible trace elements (Cr = 2031–2534 ppm, Ni = 1264–1988 ppm, Co = 76–101 ppm) similar to that which is observed in the associate serpentinite.
Análisis del cambio en la dieta mexicana: pérdida y desperdicio de alimentos en México y su impacto ambiental
Authors: Valencia-Sánchez Yamilet , González-Abraham Charlotte Elizabeth , Torres-Rojo Juan Manuel , Hernández-Ortiz Juan , Gómez-Gómez Alma Alicia , Leos-Rodríguez Juan Antonio
Published: October 2024

Objetivo: analizar la sensibilidad de la dieta mexicana ante cambios de pérdida y desperdicio de alimentos (PDA) con la finalidad de observar los efectos en el medio ambiente. Metodología: se utilizó una herramienta de modelado denominada Calculadora FABLE y datos específicos sobre PDA en México, se exploraron tres escenarios: dieta actual, dieta de transición y dieta saludable, considerando diferentes niveles de PDA para 2015, 2030 y 2050. Resultados: una dieta saludable, centrada en frutas, verduras, cereales y proteínas magras, puede mejorar la salud de los mexicanos debido a que proporciona suficientes calorías y nutrientes para cubrir las necesidades diarias requeridas. Se identificó que las dietas y el consumo calórico influyen en la reducción de PDA. Desde la perspectiva ambiental, se observó que adoptar una dieta saludable y reducir la PDA contribuye a disminuir la deforestación y las emisiones de gases de efecto invernadero (GEI) en México. Limitaciones: los datos de PDA para México son limitados. Conclusiones: la investigación resalta la importancia de promover dietas saludables y sostenibles, reduciendo la PDA como estrategia para alcanzar los objetivos de la meta 12.3 de los Objetivos para el Desarrollo Sostenible (ODS) y abordar los futuros desafíos de alimentos y la sostenibilidad ambiental.
Overview of Publications on Payment for Environmental Services: Focus on Brazilian Contributions
Authors: Prado Ana Cristina Campos , Zaro Elise Soerger , Tiezzi Rafael de Oliveira
Published: October 2024

Objective: This study aims to analyze publications on Payment for Environmental Services (PES), with a focus on Brazil's leadership and the evaluation of case studies, empirical and theoretical research in the Web of Science and SciELO databases up to April 2024.
 
Theoretical Framework: PES is discussed as a tool for environmental conservation and sustainable development, emphasizing challenges such as social inclusion and participatory governance.
 
Method: A systematic literature review was conducted, focusing on publications indexed in the Web of Science and SciELO databases up to April 2024. The exploratory research employed both quantitative and qualitative methodologies in data analysis.
 
Results and Discussion: The analysis revealed that Brazil plays a prominent role in PES publications, both nationally and internationally. Within the Brazilian context, the states of São Paulo and Minas Gerais stand out, with the Conservador das Águas project in Extrema frequently cited in the literature.
 
Research Implications: The results provide a foundation for the development of public policies aimed at expanding PES initiatives in Brazil. Mapping existing projects can encourage the replication of best practices and foster research in underexplored areas, promoting climate mitigation strategies.
 
Originality/Value: This study contributes to the literature by identifying and mapping PES projects, providing valuable insights for the formulation of strategies aimed at improving climate conditions.
Comparative Analysis of an 8 – Stage Cockcroft Walton Voltage Multiplier and A Dickson Voltage Multiplier in The Context of Radio Frequency Energy Harvesting
Authors: Udechukwu Felix Chimezie , Ahaneku Mamilus , Chijindu Vincent Chukwudi , Oyeka Dumtoochukwu , Amoke Douglas Amobi , Mbah Chiagozie
Published: October 2024

Purpose: This study seeks to enhance voltage multipliers for Radio Frequency (RF) energy harvesting, with an emphasis on increasing the efficiency of harvested energy. This improvement is vital for sustainable energy applications and reducing environmental pollution caused by fossil fuels.
 
Theoretical reference: RF energy harvesting technology is gaining recognition as a viable sustainable method for capturing ambient energy, with earlier research primarily focused on antenna and circuit design. Nonetheless, the effectiveness of energy harvesting is still constrained by inadequate power output. This study expands on prior research by directly comparing two commonly utilized voltage multipliers, the Cockcroft Walton and Dickson multipliers, in the context of RF energy harvesting.
 
Method: The Cockcroft Walton and Dickson voltage multipliers were optimally designed using Multisim and their performance was analysed using MATLAB. The comparison was conducted at an input voltage of 1V within two frequency ranges: 85 MHz – 110 MHz (FM band) and 1.8 GHz – 3.0 GHz (4G band). Output voltages for both multipliers were recorded and compared across these frequency bands.
 
Results and Conclusion: At an input voltage of 1V within the FM band (85 MHz – 110 MHz), the Dickson voltage multiplier outperformed the Cockcroft Walton multiplier, delivering an output voltage of 11.1V compared to 6.6V. However, in the 4G band (1.8 GHz – 3.0 GHz), the Cockcroft Walton multiplier was more effective, providing a maximum output voltage of 5.2V against Dickson's 4.1V. The study concludes that the Dickson multiplier is more suitable for harvesting RF energy from the FM band, while the Cockcroft Walton multiplier is better for 4G band energy harvesting.
 
Implications of research: The findings suggest that different RF energy harvesting applications may benefit from distinct voltage multipliers, depending on the frequency band in question. This could guide the design of more efficient RF energy harvesting circuits in future technologies aimed at sustainable energy solutions.
 
Originality/value: This study offers a direct comparison of two voltage multipliers under different RF frequency conditions, providing valuable insights into optimizing energy harvesting technologies for green energy applications. The results help advance the understanding of efficient circuit design for specific RF frequency bands, contributing to the development of more effective energy harvesting systems.
A importância do manejo amigável (Cat Friendly) para a prática da medicina felina
Authors: Rodrigues de Oliveira Mariana , Teixeira de Almeida Letícia , David de Sena Érico , Marques Pinheiro Rachel , Dias Pereira Samir , Rodrigues Peixoto Anna Julia , Dos Santos Lopes Fernandes Maria Eduarda
Published: October 2024

Introdução: O aumento no número de gatos domésticos trouxe à tona a necessidade de um cuidado especializado, uma vez que esses animais são mais suscetíveis ao estresse. É fundamental entender que gatos têm necessidades diferentes dos cães para oferecer um atendimento adequado. Objetivo: Avaliar o conhecimento e uso das práticas Cat Friendly por veterinários e estudantes de medicina veterinária em Valença (RJ) e regiões vizinhas. Metodologia: Estudo transversal descritivo e quantitativo com veterinários e graduandos de Valença e adjacências. Foi aplicado um questionário online, com 15 perguntas objetivas e discursivas, divulgado via Google Forms e WhatsApp, entre agosto de 2023 e maio de 2024. Discussão: A pesquisa mostrou uma crescente participação feminina na veterinária e revelou que muitos conhecem o manejo Cat Friendly, mas não de forma aprofundada. A falta de conhecimento sobre o Certificado Cat Friendly Practice aponta para uma brecha na divulgação. Embora alguns profissionais usem fármacos e feromônios para reduzir o estresse felino, a contenção física inadequada ainda é comum. Há uma consciência sobre a importância do manejo em casa, mas falta familiarização com o conceito Cat Friendly, indicando a necessidade de mais educação para tutores e profissionais. Conclusão: Identificaram-se lacunas no conhecimento sobre práticas e certificações Cat Friendly, ressaltando a necessidade de mais educação na comunidade veterinária para garantir o bem-estar dos felinos.
«БРУДУ НЕ ТЕРПИТЬ СЛОВО…» (рецензія на: Галів Уляна. Крапля твого сумління. Дрогобич: Посвіт, 2024. 116 с. )
Authors: МЕЛЬНИК ЛЮБОВ
Published: October 2024

«БРУДУ НЕ ТЕРПИТЬ СЛОВО…» (рецензія на: Галів Уляна. Крапля твого сумління. Дрогобич: Посвіт, 2024. 116 с. )
КОМПЕТЕНТНІСНИЙ ПІДХІД У ВИКЛАДАННІ МОРФЕМІКИ ТА ДЕРИВАТОЛОГІЇ У ВИЩІЙ ШКОЛІ
Authors: КОСТІВ ОКСАНА
Published: October 2024

У статті окреслено проблемні моменти, завдання, основні принципи, методи, прийоми навчання морфеміки і словотвору для формування й розвитку фахової компетенції нормативного курсу «Сучасна українська літературна мова. Морфеміка і дериватологія» для студентів другого курсу філологічного факультету ОП «Середня освіта. Українська мова та література» спеціалізації 014 01 «Середня освіта (Українська мова та література)».
ВІДТВОРЕННЯ ОБРАЗНИХ ПОРІВНЯНЬ В УКРАЇНСЬКОМУ ПЕРЕКЛАДІ РОМАНУ САРИ ГЕЙВУД «КАКТУС»
Authors: КРЕХОВЕЦЬКА СТЕФАНІЯ , АЛЬБОТА СОЛОМІЯ
Published: October 2024

У статті досліджено проблеми та стратегії перекладу образних порівнянь з англійської мови на українську в романі Сари Гейвуд «Кактус». Основну увагу приділено тому, як зберігаються емоційні та стилістичні нюанси оригінального тексту, а також ефективності різних методів перекладу. Результати дослідження показують, що точний переклад образних порівнянь вимагає тонкого балансування між збереженням первинного значення та адаптацією до культурних особливостей цільової мови. Перспективи подальшого дослідження вбачаємо в аналізі образних порівнянь в інших літературних жанрах і творах.
ВИКОРИСТАННЯ СУЧАСНИХ ТЕХНОЛОГІЙ НАВЧАННЯ ДЛЯ МОВЛЕННЄВОГО РОЗВИТКУ ДІТЕЙ СТАРШОГО ДОШКІЛЬНОГО ВІКУ
Authors: ЛУШПИНСЬКА ЛІЛІЯ
Published: October 2024

У статті розглянуто організацію та технології навчально-виховного процесу з дітьми старшого дошкільного віку. Розкрито характер використання сучасних технологій, спрямованих на мовленнєвий розвиток дітей. З’ясовано, що найдієвішими серед інноваційних технологій для дітей цього вікового цензу є технології інтерактивного та розвивального навчання. Технології інтерактивного навчання передбачають, що дитина є центральною фігурою отриманої інформації, яку сприймає, узагальнює, доповнює та відтворює. Для реалізації ідеї розвивального навчання, використовують діяльнісний підхід. Діти повинні виступати в ролі активних шукачів інформації, дослідників, винахідників, доповідачів, співбесідників: мінімум готових фактів і максимум активного творчого пошуку, самостійних міркувань. Закцентовано на видах діяльності, пріоритетних для формування мовленнєвої компетентності: навчально-мовленнєвій, мовленнєво-ігровій, комунікативно-мовленнєвій, художньо- мовленнєвій. Доведено, що ефективними методами роботи, спрямованими на розвиток мовлення дітей старшого дошкільного віку є робота з літературними творами (слухання, вивчення напам’ять, літературно-художній аналіз прозових текстів та віршів), мовленнєві завдання і вправи на основі дидактичної наочності, бесіди та розповіді за змістом картин, дидактичні ігри, спостереження, екскурсії. Основною метою дошкільного навчання української мови визначено збагачення словникового запасу дітей та розвиток зв’язного мовлення.
Agronomic Prevention of Pre-Harvest Mycotoxin Contamination in Foods: A Review
Authors:   University Of Peradeniya, Samarajeewa Upali
Published: October 2024

Mycotoxins, the antinutrients contaminating foods, continue to be an unsolved food safety hazard originating from the field. There is much attention on detoxification of contaminated foods by a variety of methods, with little success in commercialization of the findings.
Mind-Sets in Brazil Regarding the Perceptions of Stevia and Sucralose to Replace Sugar in Food: Using Generative AI and Mind Genomics Thinking to Generate Hypotheses and Insights
Authors:   Cognitive Behavioral Insight, R Moskowitz Howard
Published: October 2024

The paper presents the use of generative AI to explore the mind-sets of consumers in Brazil regarding the increasing use of high potency sweeteners. Through simulation and synthesis by AI, the paper shows how to generate deep knowledge regarding the mind-sets, how to simulate a town-hall question and answer session with these mind-sets, and what happens when these mind-sets go shopping (shop-along).
Does Eating Disorders and Flexible Dietary Control Effects the Food Craving Arise?
Authors:   Gazi University, Ayhan Busra
Published: October 2024

It is a hypothesis often thought that food craving may be associated with particularly strict dietary control. However, it is often not thought that a similar situation can be associated with flexible diet control, and even that it can even lead to eating disorder. Therefore, research on flexible diet control and food craving has been very limited to date.
Impact of Tuber Section, Steeping Solution, and Concentration on Physicochemical Properties of Yam (Dioscorea rotundata) Flour
Authors:   Federal University Of Technology, Chibuzo Iheagwara Marcquin
Published: October 2024

This study examined various factors such as Tuber Cutting (TC), Tuber Processing Method and Duration (TPM and TPD), Soaking Solution Type and Concentration (SST and SSC), as well as Parameter Analytical Temperature (PAT) on flour samples prepared from different parts of yam tubers.
Lipoma of the Parotid Gland Extending from the Superficial to the Deep Lobe: Case Report
Authors:   Hassan Ii University
Published: October 2024

Lipoma is a benign mesenchymal tumor composed largely of fat tissue. It is one of the most common of all neoplasms, but its occurrence in the parotid gland is extremely rare.
Antisemitism, Diversity, Equity, and Inclusion: A Complex Nexus
Authors:   Rutgers Robert Wood Johnson Medical School, Ashley Wackym Phillip
Published: October 2024

Antisemitism, Diversity, Equity, and Inclusion (DEI) are interconnected elements of a multifaceted societal landscape. The term "antisemitism" refers to prejudice, discrimination, and hatred directed towards Jewish individuals, while "diversity" highlights the importance of recognizing and embracing differences among people.
Tumor Hyperprogression in Squamous Cell Carcinomas of Head and Neck after Immunotherapy: Our Perspective
Authors:   Perelman School Of Medicine At The University Of Pennsylvania, Chawla Sanjeev
Published: October 2024

Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common cancer worldwide. Although there have been some advances in multimodality therapy, the overall 5-year survival rate remains poor approximately at 40%-50%. Currently, Immune Checkpoint Inhibitor (ICI) based Immunotherapies are being evaluated as an alternate treatment modality for recurrent/metastatic HNSCCs in clinical trials.
Study on the Effect of Acupuncture Point Embedding on the Behavior of Rats with Allergic Rhinitis and its Mechanism of Action
Authors:   Chengdu University Of Traditional Chinese Medicine, Qinxiu Zhang
Published: October 2024

To observe the interventional effect of Yingxiang acupoint embedding on the behavior of rats with allergic rhinitis and the effect on the levels of serum inflammatory factors IgE, sIgE, IL-4, and IL-5.
The Public Safety Risk of Hemp Products Sold at Unlicensed Retailers
Authors:   Analytical Forensic Testing Laboratory, Bash Jennifer
Published: October 2024

New cannabinoid products are being sold by unregulated retailers and marketed toward minors across the city of Chicago. A variety of both edible and plant cannabinoid products were analyzed to explore how well the contents of the products matched their packaging and labeling.
A Pharmacovigilance Study of the Association between Antineoplastic Agents and Neutropenia Adverse Events Based on Food and Drug Administration Adverse Event Reporting System Data
Authors:   The First People’s Hospital Of Changzhou, Chen Rong
Published: October 2024

Neutropenia is one of the most common adverse events associated with antineoplastic agents. However, comprehensive real-world studies on the relationship between antineoplastic agents and neutropenia are relatively scarce.
Queering Striated Food Politics: Tropical Postg(l)ocal Precarity in Romesh Gunesekera’s Reef
Authors: Ghosal Abhisek
Published: October 2024

The inoperativity of striated narratives of food politics stands caught up by patriarchal practices of identity formation entailing codification of different sexualities in terms of ‘rigid’ territories and strata and therefore cannot but conform to the irresistible snares of tropical postg(l)ocal precarity embodied by the disseminating strands of neoliberal capitalism. It thus calls for the actualization of queering to decimate ‘rigid segmentarities’ of striated food politics, which seeks to work in tandem with the territorializing movements of tropical postg(l)ocal precarity backed by the structures of patriarchal normativity. Queering striated food politics in the context of Sri Lanka strikes up an epistemic departure from the practices of culinary stratification of sexualities and eventually takes up rhizomatic movements both to call the nuanced liaisons between striated food politics and tropical postg(l)ocal precarity into question and suggest a ‘smooth politics’ in the form of a nomadic ‘war machine’. Queering striated food politics thus entails a strong resistance against the patriarchal culinary incarcerations of sexualities, taking substantial recourse to Romesh Gunesekera’s novel Reef.
Sissyphilia and Tropicopolitan Sensibilities: Queering the Star in Thai Boys Love Media
Authors: Prasannam Natthanai
Published: October 2024

This article investigates the queered star image in Thai Boys Love/yaoi (BL)/Y media released after 2020 through the lens of sissyphilia, queer scholarship, and a newly proposed idea—tropicopolitan sensibilities. The study concentrates on PP Krit Amnuaydechkorn’s BL-star persona. PP Krit practices his sissyphilic persona both within and beyond the Thai live-action BL framework, incorporating elements such as costume, makeup, mannerism, coupling culture, and the spectacle of diverse cultures. Arguably, sissyphilia in Thai BL media of the 2020s is no longer a mere withdrawal from gay men’s sissyphobic masculinity. Instead, it should be approached as a testament to another “queer turn” in the Thai mediascape, where an increasing number of celebrities are disrupting and diversifying Thai LGBTQ stereotypes. The BL industry in Thailand employs critical-creative maneuvers to resonate with the socio-political atmosphere of the period and embrace new tropes of transnational queer media.
Optimal energy generation of hybrid energy systems considering economic and environmental multi-objective functions
Authors: Raman Arasu , Sayed Biju Theruvil , Alkhayyat Ahmad , Ved Amit , Chetan M. , Singh Ashish , Kumar Raj , Prasad K. D. V , Sapaev I. B. , Mohammedi M
Published: October 2024

This research is dedicated to exploring and identifying the most effective design for an energy source tailored specifically to meet the electricity demands of a residential community. In an era where energy efficiency and sustainability are paramount, this study emphasizes the importance of technical and economic considerations in energy sourcing. It posits that any viable solution must not only be efficient in its energy production and consumption but also reliable in its delivery and financially feasible for the residents who will depend on it. To address this multifaceted challenge, the study proposes the innovative use of a rotation-invariant coordinate convolutional neural network in conjunction with binary battle royale optimization techniques. These advanced methodologies are selected for their potential to enhance the modelling and optimization processes involved in energy source design. The primary goal of employing these methods is to minimize two critical factors: the net present cost of the energy system and the overall energy cost incurred by the residents. By focusing on these objectives, the research aims to ensure that the proposed energy solutions are not only cost-effective but also sustainable over the long term. To rigorously test the proposed model and evaluate its performance, the research is conducted using the MATLAB platform. The study employs established methodologies and performance metrics to assess the outcomes of the model, ensuring that the findings are both credible and applicable to real-world scenarios. Through comprehensive testing and detailed analysis, this research aims to provide significant insights and actionable recommendations for the optimal design of energy sources in residential areas. By contributing to the ongoing discourse on sustainable energy solutions, the study seeks to inform policymakers, energy planners, and community stakeholders about effective strategies for meeting residential energy demands while promoting environmental sustainability. Ultimately, the findings of this research could play a crucial role in shaping the future of energy sourcing in residential communities, paving the way for more resilient and sustainable energy systems.
Aircraft Age Limitation versus Three Indonesian Fatal Air Accidents in HFCAS Perspective
Authors: Haryono Aloysius Sigit , Sutanto Hadi
Published: October 2024

An aircraft deemed to be airworthy, not limited by aircraft age but by well maintenance and by the operation of the aircraft. The investigation by KNKT between 2014 -2021 found no statement related of aircraft aging like material fatique or other phrases. The latent errors started with repetitive failures which were not solved as early as possible. Three fatal accidents involved aircrafts with age of 27, 6 and 1 year old, all below the Minister Regulation No. 160 (2015) which stated maximum age was 30 years. The cancelation of Minister Regulation No. 027 (2020) is the correct decision from Indonesian Government as per other countries policy in term of aircraft airworthy not affected by aircraft aging. The cancelation empowers the technology innovation for old aircraft to be remanufactured which is common practise in other countries, latest technology innovation, safe operation, sustainability by reserving raw material of natural resources from scarcity. Incosistency regulations about aircraft age limit which operated since beginning in Indonesian airspace, showed that the regulations were made not based on academic or research approach.
Analisis Struktur untuk Pondasi Radar dengan Kalkulasi Finite Element
Authors: Nugraha Arief , Bachtiar Wahju Marsellinus
Published: October 2024

Artikel ini mempresentasikan dari kegiatan studi kasus yang dikerjakan penulis, diambil dari salah satu proyek yang dikerjakan penulis. Metode analisa yang digunakan adalah Finite Element yang terdapat pada dokumen design review yang dikeluarkan oleh Naval Architect. Dari hasil analisa tersebut dapat di ketahui bahwa secara konsep disain ada perubahan dari disain as is yaitu plat & tulangan existing dengan improvement design yaitu dengan mengganti plat & tulangan existing. Dengan begitu dapat di simpulkan bahwa design as is dengan plat T 4,5 mm jika di simulasi dengan Finite Element ada warna merah di bagian knuckle yang menandakan kekuatan struktur kurang begitu baik, berbeda dengan konsep improvement yaitu dengan mengganti plat as is menjadi 2 kali lebih tebal yaitu ke plat T 8 mm yang di peroleh hasil pada Finite Element menjadi warna hijau, dengan perubahan warna dari merah ke hijau di simulasi software tersebut, dapat di simpul kan bahwa dengan mengganti plat & tulangan pada posisi knuckle, secara struktur akan lebih kuat dan kaku sebagai Pondasi Radar.
Pelaksanaan Bimbingan Teknis SiTB (Siap Tangguh Bencana) di Provinsi NTB
Authors: Wijaya Hendy Risdianto , Pandjaitan M.M. Lanny W. , Lukas  , Simatupang Frederick
Published: October 2024

Artikel ini mempresentasikan kegiatan praktik keinsinyuran dalam penggunaan aplikasi SiTB (Siap Tangguh Bencana) untuk menghasilkan pelaporan SPM Sub Urusan Bencana di Provinsi NTB. Kegiatan ini berupa Bimbingan Teknis (BimTek) kepada BPBD Provinsi, BPBD Kab/Kota dan pihak terkait; yang dilaksanakan dengan 2 cara yakni daring pada 6 Juni 2023 melalui zoom dan secara luring pada 20 sampai 22 Juni 2023 di Fave Hotel Langko Mataram. Kegiatan ini merupakan hasil kerjasama dari Kementerian Dalam Negeri Dirjen Bina Adwil, Pemerintah Provinsi NTB dan SIAP SIAGA. Tujuan kegiatan ini adalah peserta bisa mengisi data sesuai petunjuk pengisian SPM di SiTB dan menghasilkan laporan SPM tahun 2022. Laporan tersebut dapat digunakan sebagai dokumen perencanaan pembiayaan BPBD Kab/Kota dan juga dapat menjadi bahan evaluasi bagi BPBD Provinsi dan Pemda NTB dalam Penanggulanan Risiko Bencana (PRB).
Penerapan Algoritma Hue Saturation Intensity (HIS) dengan Ruang Warna Red, Green, Blue (RGB) dan Implementasi Aplikasi Kematangan Buah Tomat
Authors: Yanto Budi , Kartawidjaja Maria Angela , Sukwadi Ronald
Published: October 2024

Tomat, sebagai salah satu jenis sayuran atau buah, sering kali rentan terhadap kerusakan, menjadikan penanganannya tantangan yang kompleks. Membedakan antara buah tomat yang masih segar dan yang sudah rusak menjadi sangat penting, mengingat dampak yang signifikan pada nilai gizi dan aspek ekonomisnya. Dalam konteks ini, diterapkan perhitungan HSI (Hue, Saturation, Intensity) untuk mengukur transformasi warna dan ruangan RGB. Hasil penelitian menunjukkan nilai HSI untuk masing-masing kelas, dengan kelas tomat matang memiliki rata-rata hue 0.0051 – 0.026, saturation 0.1862 – 0.3291, dan intensity 0.0975 –0.7522. Tomat setengah matang memiliki hue 0.0208 – 0.0848, saturation 0.1346 – 0.5746, dan intensity 0.1056 – 0.4714, sementara tomat belum matang memiliki hue 0.0174 – 0.0689, saturation 0.0474 – 0.2072, dan intensity 0.0595 – 0.3203. Integrasi langkahlangkah algoritma HSI dengan ruang warna RGB memberikan dimensi tambahan pada analisis warna, yang berpotensi meningkatkan ketepatan deteksi kematangan buah tomat.
Analisis Efek Aliasing Pada Sinyal Audio Dengan Variasi Frekuensi Sampling Pada Lagu ‘Terhebat’
Authors: Shabrina Hasyyati , Setyowati Endah , Ahmayani Inda , Putri Khalifah Audya Eka
Published: October 2024

Aliasing merupakan fenomena yang terjadi dalam pengolahan sinyal digital, termasuk sinyal audio, ketika frekuensi sampling yang digunakan tidak mencukupi untuk merepresentasikan frekuensi tertinggi dalam sinyal tersebut. Penelitian ini bertujuan untuk menganalisis efek aliasing pada sinyal audio dengan melakukan variasi frekuensi sampling pada lagu "Terhebat". Eksperimen dilakukan dengan menggunakan software MATLAB untuk memvisualisasikan dan menganalisis sinyal audio pada frekuensi sampling 11025 Hz, 22050 Hz, 44100 Hz, 88200 Hz, dan 32000 Hz. Hasil penelitian menunjukkan bahwa frekuensi sampling yang terlalu rendah, seperti 11025 Hz dan 22050 Hz, menyebabkan aliasing yang signifikan, ditandai dengan distorsi dan hilangnya detail frekuensi tinggi pada sinyal audio. Sebaliknya, frekuensi sampling yang terlalu tinggi, seperti 88200 Hz, tidak memberikan manfaat yang signifikan dalam meningkatkan kualitas audio. Frekuensi sampling 44100 Hz, yang umum digunakan dalam CD audio, menghasilkan kualitas audio yang baik dengan efek aliasing yang minimal. Penelitian ini menyimpulkan bahwa pemilihan frekuensi sampling yang tepat sangat penting untuk menghindari efek aliasing dan mempertahankan kualitas sinyal audio yang baik.
Патология генов гистоновых лизин-метилтрансфераз и характерные эписигнатуры
Authors: Земляная О.А. , Ефремова А.В. , Володин И.В. , Залетаев Д.В.
Published: October 2024

Согласованная работа эпигенетических механизмов регуляции экспрессии генов (метилирования ДНК, модификаций гистонов, воздействия некодирующих РНК) обеспечивает своевременное и поэтапное развитие тканей и органов. Показано, что повреждение одного звена эпигенетической регуляции приводит к изменению функционирования других ее составляющих. За последние 10 лет было открыто более 60 эпигеномных сигнатур – уникальных паттернов метилирования генома, характерных для наследственных заболеваний, ассоциированных с нарушением эпигенетического аппарата. Эписигнатура может частично обусловливать фенотипические проявления, а также потенциально служить диагностическим инструментом ввиду своей высокой специфичности. В настоящем обзоре предлагается рассмотреть одно из центральных звеньев эпигенетической регуляции – метилирование гистоновых белков, а также наследственные заболевания, развивающиеся при его нарушении, и характерные для данных синдромов эписигнатуры.

Time-appropriate, stage-by-stage development of tissues and organs is achieved by coordinated operation of epigenetic mechanisms of gene expression regulation (DNA methylation, histone modifications, effects mediated by non-coding RNAs). It has been established that disruption of one single component of epigenetic regulation leads to changes in the functioning of others. Over the past 10 years there have been discovered more than 60 epigenomic signatures representing unique genome methylation patterns specific for hereditary disorders associated with disruption of the epigenetic machinery. The episignature can partially determine phenotypic traits and potentially serve as a reliable diagnostic tool due to its high specificity. This review aims to shed light on one of the central links of epigenetic regulation, histone methylation, as well as hereditary diseases that develop when it is disrupted, and the episignatures specific for these syndromes.
Effects of GSTP1 and GPX4 genetic variants and their gene-gene interaction on the severity of COVID-19
Authors: Eid M.A. , Aleksandrova A.A. , Zatonsky S.A. , Gutnikova L.V. , Shkurat T.P.
Published: October 2024

Background. Coronavirus disease 2019 (COVID-19) is a highly contagious disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several risk factors of COVID-19 susceptibility and severity are associated with oxidative stress. Aim: to investigate the association of single nucleotide polymorphisms (SNPs) of glutathione S-transferase pi-1 (GSTP1) and glutathione peroxidase 4 (GPX4) genes with the severity of COVID-19. Methods. Study subjects were divided into two groups based on the severity of their symptoms. Allele-specific real time polymerase chain reaction (RT-PCR) was used for genotyping, and multifactor dimensionality reduction (MDR) analysis was performed to investigate the SNP-SNP interaction models. Results. The results showed a significant association of GPX4 rs713041 with the severity of COVID-19 (p=0.035). Most of GPX4 718TT carriers had a severe course of COVID-19 (OR=3.50; 95% CI [1.18-10.35]). The resulted three-locus SNP-SNP interaction model was statistically significant (p=0.0084, OR = 2.42; 95% CI [1.24 - 4.73]). Linkage disequilibrium analysis of GSTP1 SNPs rs1695 and rs1138272 showed a high possibility of linkage disequilibrium between the two sites (D’ = 0.949). Conclusions: To our knowledge, this is the first study to investigate the association of GSTP1 rs1695, GSTP1 rs1138272, and GPX4 rs713041 and SNP-SNP interaction with the severity of COVID-19 symptoms. The obtained results may serve as a novel potential factor of COVID-19 prognosis.

Введение. Коронавирусное заболевание 2019 (COVID-19) – высококонтагиозное заболевание, вызываемое коронавирусом SARS-CoV-2. Несколько факторов риска восприимчивости и тяжести COVID-19 связаны с окислительным стрессом. Целью настоящего исследования было изучение ассоциации однонуклеотидных полиморфизмов (SNP) генов глутатион S-трансферазы pi-1 (GSTP1) и глутатионпероксидазы 4 (GPx4) с тяжестью заболевания COVID-19. Методы. Пациенты были разделены на две группы в зависимости от тяжести симптомов. Для генотипирования использовалась аллель-специфическая полимеразная цепная реакция в реальном времени (RT-PCR). Для исследования межгенных взаимодействий проводился MDR-анализ (multifactor dimensionality reduction). Результаты. Показана значимая ассоциация GPX4 rs713041 с тяжестью течения COVID-19 (p=0,035). У большинства носителей генотипа GPX4 718 (TT) было тяжелое течение COVID-19 (ОШ=3,50; 95% ДИ [1,18-10,35]). Трехлокусная модель взаимодействия SNP-SNP была статистически значимой (p = 0,0084, ОШ = 2,42; 95% ДИ [1,24–4,73]). Анализ неравновесия по сцеплению GSTP1 rs1695 и rs1138272 показал высокую вероятность неравновесия по сцеплению между двумя сайтами (D’ = 0,949). Выводы. Насколько нам известно, это первое исследование ассоциаций и межгенных взаимодействий GSTP1 rs1695, GSTP1 rs1138272 и GPX4 rs713041 с тяжестью симптомов COVID-19. Полученные результаты могут служить новым потенциальным фактором прогноза COVID-19.
Христианизация права в Византийской империи (на примере Эклоги)
Authors: Смирнов А.И.
Published: October 2024

В статье описывается отражение процесса постепенной христианизации византийского законодательства в памятнике византийского права — Эклоге. Автор проводит разносторонний анализ данного документа, отмечая виды рассмотренных в нем правовых отношений, предписанную им систему наказаний, его связь с социально-экономическим строем, а также указывая на дополнявшие его и заменившие его правовые документы.

The article describes the reflection of the process of gradual Christianization of Byzantine legislation in such monument of Byzantine law as Eclogue. The author makes a comprehensive analysis of this document noting the types of legal relations considered in it, the system of punishments prescribed by it, its connection with the social and economic system and also pointing to the legal documents that supplement it and replace it.
Правовое регулирование натуральной помощи детям-инвалидам в Российской Федерации
Authors: Семянникова Д.А.
Published: October 2024

В статье исследуется правовое регулирование натуральной помощи детям-инвалидам, а также семьям, воспитывающим ребенка-инвалида, выражающейся в передаче субъекту-получателю предметов в «овеществленной форме». Актуальность исследования правового регулирования натуральной помощи обусловлена серьезной потребностью детей-инвалидов в данном виде социальной поддержки. Отмечен ряд особенностей оказания подобной помощи семьям с детьми-инвалидами, где характерным признаком является ее неденежный характер, который позволяет достичь цели удовлетворения определенной потребности семьи с ребенком-инвалидом прямо, а не опосредованно, что значительно повышает эффективность расходования бюджетных средств.

The article examines the legal regulation of in-kind aid to children with disabilities as well as to families raising a disabled child expressed in the transfer to the recipient subject of subjects in «materialized form». The relevance of the study of the legal regulation of in-kind aid is stipulated by the serious need of children with disabilities in this type of social support. A number of features were noted to provide such assistance to families with disabled children, where the characteristic feature is its non-monetary nature which makes it possible to achieve the goal of meeting the specific needs of a family with a disabled child directly and not indirectly, which significantly increases the efficiency of budget spending.
Феномен реанимации мифогенеративных структур сознания в условиях социально-сетевой активности
Authors: Галухин А.В.
Published: October 2024

В статье выявляются предпосылки реанимации структур мифологического сознания и факторы распространения современных мифов, складывающиеся в процессе развития интерактивных форм социально-сетевого общения. Определяются условия проявления диспозиций к мифотворчеству на уровне саморепрезентации личности в социально-сетевом киберпространстве. Рассматриваются когнитивно-стилистические трансформации, определяющие восприимчивость к продуктам сетевого мифотворчества, демонстрируется релевантность условиям мифогенеративной активности новых форм языка сетевого общения.

The article considers the prerequisites for resuscitation of the structures of mythological consciousness and the factors of the dissemination of modern myths, emerging in the process of developing interactive forms of social networking. The conditions for the manifestation of dispositions to myth creation at the level of self-representation of the individual in the social network cyberspace are determined. The article examines cognitive-stylistic transformations that determine susceptibility to the products of network myth-making, demonstrates the relevance to the conditions of the myth-generating activity of new forms of the network language.