bluuebunny/crossref_metadata_2025 huggingface dataset:
استثمار الوقف العلمي بالجامعات السعودية: صندوق وقف جامعة الملك فهد للبترول والمعادن نموذجاً
Authors: Al-Shariff Muhammad
Published: December 2019

تهدف هذه الدراسة إلى التعرف على استثمار الوقف العلمي بالجامعات السعودية من خلال تجربة صندوق وقف جامعة الملك فهد للبترول والمعادن، وتقويم أدائه الاستثماري، وتعتمد الدراسة على المنهج الوصفي في بيان أهداف الصندوق واستراتيجيته الاستثمارية، وما حققه من إنجازات، كما تستخدم المنهج التحليلي في تقويم استثمارات جامعة الملك فهد، وتوزيع محفظته الاستثمارية، وكفاءته مقارنة بمثيلاته من الصناديق الاستثمارية لمجموعة مختارة من الجامعات الأمريكية، وأوضحت نتائج الدراسة أنَّ صندوق الوقف جامعة الملك فهد استثمر أمواله بكفاءة وفقاً للاستراتيجية التي وضعت لتحقيق أهدافه، والقائمة على التوافق مع أحكام الشريعة الإسلامية، حيث تتنوع استثمارات الصندوق بين عمليات المرابحة والصكوك والأسهم المحلية والإقليمية والدولية والاستثمارات البديلة كالعقارات وحقوق الملكية الخاصة والسلع وصناديق التحوط، وأكدت نتائج الدراسة أنَّ صندوق وقف جامعة الملك فهد حقق منذ إنشائه نمواً مستمراً، وزادت أصول محفظتيه النقدية والعقارية، وبينت أنَّ توزيع المحفظة الاستثمارية للصندوق كان مشابهاً لما هو سائد لدى بعض أوقاف الجامعات الأمريكية من حيث نمط وأسلوب توزيع المحفظة الاستثمارية مع زيادة في استثمارات الأسهم؛ مما يدل على كفاءة إدارة استثمارات وقف جامعة الملك فهد، وخلصت الدراسة إلى جملة من المقترحات بشأن تطوير استثمار الوقف العلمي بالجامعات السعودية، وزيادة مساهمته في خدمة المجتمع. الكلمات المفتاحية: الوقف العلمي، استثمار الأوقاف، صندوق الوقف، المحفظة الاستثمارية، الجامعات السعودية.
Sulfur Removal from Dibenzothiopheneby Newly Isolated Paenibacillusvalidus Strain PD2 and Process Optimizationin Aqueous and Biphasic (Model-Oil) Systems
Authors: DERIKVAND PEYMAN , ETEMADIFAR ZAHRA , SABER HOSSEIN
Published: December 2019

Dibenzothiophene (DBT) is an organic sulfur compound which remains in oil after hydrodesulfurization (HDS) process and can be removed by biodesulfurization (BDS). A new strain of Paenibacillus validus (strain PD2) was isolated from oil contaminated soils that is able to desulfurize DBT. HPLC analysis and Gibbs assay showed that this strain was capable to convert DBT to 2-Hydroxybiphenyl (2-HBP) as final product. The presence of dszC gene confirmed that DBT desulfurization occurred through the 4S pathway. Maximum growth and the highest induction in dsz operon obtained in the presence of dimethyl sulfoxide (DMSO) as sole sulfur source. DBT concentration, temperature and pH were optimized statistically for growing and resting cells by using Response Surface Methodology (RSM). All parameters in growing cells had a significant effect on 2-HBP production during BDS of DBT by P. validus PD2, although in resting cells temperature in range of 20-40 degrees C was not a significant factor. Maximum BDS for growing cells was obtained at 0.41 mM DBT concentration, pH 6.92 and temperature 31.23 degrees C. For resting cells, optimum pH, temperature and DBT concentration were 6.62, 27.73 degrees C and 7.86 mM respectively. The results of this study showed that high concentrations of DBT could be desulfurized by P. validus strain PD2 in model-oil. Thus, the isolated strain could be introduced as a proper candidate for biodesulfurization of organic sulfur in the oil industry.
Recombinant MAG1 Protein of Toxoplasma gondii as a Diagnostic Antigen
Authors: GATKOWSKA JUSTYNA M. , DZIADEK BOŻENA , DZIADEK JAROSŁAW , DZITKO KATARZYNA , DŁUGOŃSKA HENRYKA
Published: December 2019

The aim of this study was to evaluate the potential diagnostic usefulness of the full-length recombinant Toxoplasma gondii MAG1 protein by determining the levels of specific IgM and IgG antibodies in mouse and human sera obtained from individuals with acute and chronic toxoplasmosis. The obtained results revealed that IgG antibodies against MAG1 are a sensitive and specific marker of T. gondii infection since the protein was recognized by both mouse and human sera, 100% and 94.3%, respectively, rendering the full-length rMAG1 a prospective alternative for the polyvalent native antigen (TLA).
Kinetic properties of pyruvate ferredoxin oxidoreductase of intestinal sulfate-reducing bacteria Desulfovibrio piger Vib-7 and Desulfomicrobium sp. Rod-9
Authors: KUSHKEVYCH IVAN V.
Published: December 2019

Intestinal sulfate-reducing bacteria reduce sulfate ions to hydrogen sulfide causing inflammatory bowel diseases of humans and animals. The bacteria consume lactate as electron donor which is oxidized to acetate via pyruvate in process of the dissimilatory sulfate reduction. Pyruvate-ferredoxin oxidoreductase activity and the kinetic properties of the enzyme from intestinal sulfate-reducing bacteria Desulfovibrio piger and Desulfomicrobium sp. have never been well-characterized and have not been yet studied. In this paper we present for the first time the specific activity of pyruvate-ferredoxin oxidoreductase and the kinetic properties of the enzyme in cell-free extracts of both D. piger Vib-7 and Desulfomicrobium sp. Rod-9 intestinal bacterial strains. Microbiological, biochemical, biophysical and statistical methods were used in this work. The optimal temperature (+35°C) and pH 8.5 for enzyme reaction were determined. The spectral analysis of the puri- fied pyruvate-ferredoxin oxidoreductase from the cell-free extracts was demonstrated. Analysis of the kinetic properties of the studied enzyme was carried out. Initial (instantaneous) reaction velocity (V0), maximum amount of the product of reaction (Pmax), the reaction time (half saturation period) and maximum velocity of the pyruvate-ferredoxin oxidoreductase reaction (V ) were defined. Michaelis constants (Km) of the enzyme reaction were calculated for both intestinal bacterial strains. The studies of the kinetic enzyme properties in the intestinal sulfate-reducing bacteria strains in detail can be prospects for clarifying the etiological role of these bacteria in the development of inflammatory bowel diseases.
The application of impedance microsensors for real-time analysis of Pseudomonas aeruginosa biofilm formation
Authors: CHABOWSKI KONRAD , JUNKA ADAM FELIKS , SZYMCZYK PATRYCJA , PIASECKI TOMASZ , SIERAKOWSKI ANDRZEJ , MĄCZYŃSKA BEATA , NITSCH KAROL
Published: December 2019

Biofilms formed by nosocomial pathogens represent a major threat to patients undergoing invasive procedures. As prophylaxis remains the most efficient anti-biofilm option, it is of paramount importance to develop diagnostic tools able to detect biofilm at the early stage of formation. The present study investigates the ability of impedance microsensors to detect Pseudomonas aeruginosa biofilm presence using the impedance spectroscopy method. The measured data were analyzed using Electrical Equivalent Circuit modelling (EEC). It allowed to recognize conduction and polarization phenomena on the sensors surface and in its environment. The impedance assay results, confirmed by means of electron microscopy and quantitative cultures, indicate that specific EEC parameters may be used for monitoring the development of pseudomonal biofilm.
Investigation of the actual causes of hip joint implant loosening classified as aseptic – analysis of microbiological culture results and levels of inflammatory markers
Authors: STRZELEC-NOWAK DAGMARA , KOZIOŁ-MONTEWKA MARIA , NIEDŹWIADEK JUSTYNA , BOGUT AGNIESZKA , BLACHA JAN , MAZURKIEWICZ TOMASZ
Published: December 2019

Loosening of the hip joint prosthesis is considered as one of the most significant postoperative complications in recent years. The laboratory diagnostic procedure used to differentiate periprosthetic infection from aseptic loosening is very difficult because of the biofilm which microorganisms form on the implant surface. The purpose of this research was to evaluate the level of concordance between clinical classification of implant loosening among 50 patients subjected to reimplantation procedure and laboratory investigation of PJI including microbiological culture results and the levels of inflammatory markers assessed in the patients' synovial fluid samples, serum, and full blood. The synovial fluid was collected for leukocyte count, differential cell count, and culture on standard media. The levels of systemic inflammation markers such as the ESR and CRP concentration were determined in serum and full blood. Tissue samples were collected for microbiological studies. Components from endoprostheses were exposed to ultrasound in a process called sonication. Among the parameters measured in serum and full blood the levels of ESR and CRP were higher in the septic group of patients. Cytologic analysis of synovial fluid was in correlation with microbiologic identification. The most frequent isolated bacteria was Staphylococcus epidermidis. Culture results from materials such as synovial fluid, sonicate and tissues are crucial to establish the infectious aetiology of the loosening. Microscopic analysis of synovial fluid represents a simple, rapid and accurate method for differentiating PJI from aseptic failure. Sonication increases detection of the infectious process, and culture results are in correlation with the cytologic analysis of synovial fluid.
Biologically-induced precipitation of minerals in a medium with zinc under sulfate-reducing conditions
Authors: WOLICKA DOROTA , BORKOWSKI ANDRZEJ , JANKIEWICZ URSZULA , STĘPIEŃ WOJCIECH , KOWALCZYK PAWEŁ
Published: December 2019

Sulfate-reducing microbial communities were enriched from soils collected in areas with crude-oil exploitation. Cultures were grown in modified Postgate C medium and minimal medium, with ethanol or lactate as an electron donor. The batch cultures were grown with addition of zinc in concentrations of 100-700 mg/l. A lack of increased protein concentration in the solutions compared with the control batch, was noted in cultures containing over 200 mg Zn2+/l. The 16S rRNA method was applied to determine the specific composition of the selected microorganism communities. The analysis indicated the presence of Desulfovibrio spp., Desulfobulbus spp. and Desulfotomaculum spp. in the communities. Diffractometric analysis indicated the presence of biogenic sphalerite in cultures with 100 and 200 mg Zn2+/l and elemental sulfur in cultures with 200 mg Zn2+/l. Other post culture sediments (300-700 mg Zn2+/l) contained only hopeite [Zn3(PO4)2·4H2O] formed abiotically during the experiment, which was confirmed by studies of the activity of sulfate-reducing microbial communities.
Isolation and antimicrobial testing of Aeromonas spp., Citrobacter spp., Cronobacter spp., Enterobacter spp., Escherichia spp., Klebsiella spp., and Trabulsiella spp. from the gallbladder of pigs
Authors: EVANGELOPOULOU GRAMMATO , FILIOUSSIS GEORGIOS , KRITAS SPYRIDON , KANTERE MARIA , BURRIEL ANGELIKI R.
Published: December 2019

The presence of Gram-negative bacteria species, other than Salmonella spp., in the gallbladder of pigs was examined. Isolated Gram-negative bacteria were assigned to species using the Microgen™ GnA+B-ID Systems. Of the 64 isolated strains 43 were identified as Escherichia coli, seven as Enterobacter spp., three each as Klebsiella spp., Citrobacterfreundii, Aeromonas hydrophila and Cronobacter sakazakii and one each as Escherichiafergusonii and Trabulsiella guamensis. Their antibiograms showed very high resistance to ampicillin, amoxicillin, tetracycline, chloramphenicol and sulfamethoxazole/trimethoprim. It was concluded that the pigs' gallbladder is a reservoir of potentially pathogenic Gram-negative bacteria for pork consumers.
STUDI KEEKONOMIAN PEMANFAATAN TANDAN KOSONG KELAPA SAWIT PADA PEMBANGKIT LISTRIK BIOMASSA MUARO JAMBI
Authors: Djufri S. Umar
Published: December 2019

Limbah padat dari perkebunan kelapa sawit dan pabrik kelapa sawit berupa tandan kosong (Cangkang kosong) atau tandan kosong  kelapa sawit  ( TKKS ) dapat dimanfaatkan sebagai sumber energi alternatif pada Pembangkit Listrik Tenaga Biomassa. Tandan Kosong kelapa sawit memiliki energi sebesar 4.492,2 kkal/kg setara dengan 1,163 WH ( 1kkal = 4.187 Joule) dan dimanfaatkan sebagai bahan bakar pada pembangkit listrik tenaga Biomassa yang digunakan untuk memanaskan air di dalam boiler, sehingga menghasilkan suhu uap dan tekanan uap yang memutar turbin uap . Turbin uap berfungsi sebagai prime mover untuk memutar generator , sehingga menghasilkan output berupa daya listrik . Dengan menjelaskan secara teknis dan keekonomisan pemanfaatan limbah padat tandan kosong di pabrik kelapa sawit PT. BAM di Kabupaten Muaro Jambi , Provinsi Jambi , untuk pembangkit listrik dan listrik dapat dijual ke PT. PLN ( Persero).Hasil Penelitian dari analisis perhitungan biaya produksi listrik yang didapat berdasarkan suku bunga 6 %, 9 % dan 12 % adalah Rp. 572,67 /kWh , Rp. 680,67/ kWh dan Rp. 814,32 /kWh , sedangkan rata- rata tarif dasar listrik adalah Rp. 1.500/ kWh . Dengan pemanfaatan tandan kosong kelapa sawit yang dihasilkan PKS PT . BAM ini merupakan salah satu upaya untuk mengurangi limbah dan merupakan salah satu upaya untuk mengurangi limbah dan merupakan diversifikasi bisnis hilir dari pabrik kelapa sawit dapat menghasilkan sekitar 18.867,84 MWh per tahun dengan investasi sekitar 2,67 (Million USD) dapat menarik para investor. Berdasarkan tarif tenaga listrik kelapa sawit PT. BAM , maka mendapat hasil penjualan tenaga listrik ke PT.  PLN Persero adalah sebesar 1.572,31 MWh perbulan atau Rp.  1,45 Milyar ( 6 % ), Rp. 1,29 Milyar ( 9%) dan Rp. 1,08 Milyar ( 12 % ) perbulan .
Психологічні особливості впливу конформізму на виникнення наркотичної та алкогольної залежності студентів
Authors: Михайлишин Уляна , Шмідзен Ірина , Юхименко Інна
Published: December 2019

Розглянуто психологічні особливості наркотичної та алкогольної залежності особистості у підходах науковців. Висвітлено основні погляди щодо психологічних особливостей конформної поведінки особистості. Представлено та проаналізовано результати емпіричного дослідження впливу конформізму на формування наркотичної та алкогольної залежності у студентів з подальшою статистичною обробкою даних.
Методи. При досліджені були використані статистичні методи обробки даних (кореляційний аналіз за Пірсоном, Н-критерій Крускалла-Уоллеса). Були використані наступні психодіагностичні методики: методика «Схильність до залежної поведінки» В. Д. Менделевич; методика «Q-сортування»В. Стефансон; методика «Конформність-навіюваність» (С.В.Клаучек, В.В.Деларю).
Результати. В результаті теоретичного аналізу виявлено, що існує багато підходів щодо визначення адиктивної поведінки особистості, єдиної думки щодо виникнення залежності на даний час не існує. За результатами емпіричного дослідження з’ясовано, що чим більша в людини буде схильність до конформізму в цілому, тим більше можуть формуватись наркотична та алкогольна залежність. Визначено, що високий рівень конформізму може впливати на виникнення алкогольної та наркотичної залежності.
Висновки. Узагальнено основні підходи щодо виникнення залежності, визначено, що на формування наркотичної та алкогольної залежності може впливати конформна поведінка особистості.
Особливості мотиваційних тенденцій користувачів мережі інтернет
Authors: Юрчинська Ганна , Степаненко Ольга
Published: December 2019

Стаття присвячена висвітленню проблеми сталих мотиваційних тенденцій та спрямованості на певні емоційні переживання в залежності від рівня виразності «мережеголізму». Розкриті статево-вікові особливості схильності до Інтернет-залежності, які узгоджуються з тенденціями існуючих наукових досліджень, але стосуються вікової групи від 12 – 17 років (добірки, яка була в наявності). Суттєве значення має дія двоєдиного фактору «стать - вік». Встановлено, що середні показники в осіб жіночої статі мають тенденцію до зниження з віком, а в осіб чоловічої статі, навпаки, спостерігається збільшення значень схильності до адикції зі збільшенням віку.
Порівняльний аналіз дозволив виявити особливості сталих тенденцій особистості для двох груп осіб: тих, які вміють контролювати свій час перебування в Інтернеті й тих, які мають деякі проблеми з надмірним захопленням вказаною мережею. Особливості полягають у різній ієрархії зв’язків, зокрема: для осіб, які здатні контролювати свій час перебування в мережі, домінуючим є зв’язок рівня «мережеголізму» із мотивацією принести суспільству користь; для осіб, які мають деякі проблеми з надмірним захопленням Інтернетом, домінуючим є зв’язок досліджуваної ознаки (Інтернет-залежноті) з мотивами комфорту.
Встановлені особливості спрямованості на емоційні переживання в залежності від рівня адикції. Особливість - це обернена картину для досліджуваних груп: для першої домінуючою є спрямованість на емоційні переживання стенічного типа, тоді як для другої – спрямованість на емоційні переживання астенічного типу.
PRIMARY AND SECONDARY SCHOOL STUDENTS’ KNOWLEDGE RELATED TO RENEWABLE ENERGY AND SOME OF ITS INFLUENCING FACTORS
Authors: Revák Ibolya Markóczi , Jász Erzsébet , Kovács Enikő , Teperics Károly , Ütő Visi Judit , Máth János
Published: December 2019

Shaping attitude related to renewable energy resources is the task of the entire society and in the case of students of different ages it is realized via education in and outside schools. This research concerns the analysis of the knowledge of students related to renewable energy resources, exploring the differences in the case of students in different grades and also the identification of correlations between the knowledge for renewable energy and some of its influencing factors. The research was carried out in spring 2018 with 4th (N=466) and 7th (N=529) graders in primary school and also with 11th graders (N=328) in secondary school in Hungary. Association and selection tasks applied in the research were related to knowledge of renewable energy resources and three questions concerned influencing factors. Assessment was performed based on the word association test. Results indicate poor and less stable knowledge in the case of every grade. The knowledge structure of the grades is similar, solar, water and wind are the most well-known renewable energy resources. Regarding knowledge, the type of the settlement of residence, education level of parents, school curriculum, textbook, theme weeks, project work, media and internet were important among influencing factors. Keywords: project work, renewable energy knowledge, school curriculum, theme work, word association.
AN ANALYSIS OF THE HIGH SCHOOL STUDENTS’ ABILITIES TO READ REALISTIC, CONVENTIONAL, AND HYBRID IMAGES IN GENERAL CHEMISTRY
Authors: Rončević Tamara N. , Ćuk Željka Đ. , Rodić Dušica D. , Segedinac Mirjana D. , Horvat Saša A.
Published: December 2019

This research considered students’ abilities to read images about dispersed systems, taken from the chemistry textbook. 103 high school students (37 males, 63 females, and 3 unknown) from the school “Svetozar Marković“ in Novi Sad, Republic of Serbia, were included as the research participants. Students’ abilities to suggest the titles of the realistic, conventional, and hybrid textbook images about dispersed systems, as well as their written interpretations of images contents, were examined. The collected data were analysed qualitatively, and information about students’ conceptual understandings and misunderstandings about selected chemistry topic was provided. Identified misunderstandings, some of which are the contribution of this research, gave significant results. Additionally, it was concluded that the majority of students’ difficulties were related to reading realistic textbook images. Students relied on what they literally saw in the photography without making proper connections with chemical contents about dispersed systems. The findings of the present research could be helpful for science teachers and educators, interested in how and why students use textbook images to learn science concepts. They will also alert authors and textbook illustrators to pay more attention to the selection of appropriate textbook images.
Keywords: image types, general chemistry, reading images, textbook images, visual representations.
Conflictual Diversity and Contested Cultural Heritage: Newspaper Coverage of Religion in Norway 1938–2018
Authors: Lundby Knut
Published: December 2019

The visibility and diversity of religion in selected Norwegian newspapers published in the capital of Oslo is studied in a quantitativeanalysis at ten-year intervals from 1938 to 2018, with an emphasis onthe last forty years. Recent structural transformations in the newspaper industry and editorial choices cut the number of articles on religionconsiderably in 2018 compared to earlier years. However, the relativevisibility of religion in the share of the total editorial output is fairlystable, at about 1.5 per cent of the content. Rather, the changes havebeen with the diversity and criticism of religion. The representationof Islam has strongly increased, while the newspapers have playeddown the coverage of the Lutheran majority church. The conflictualdiversity and contested cultural heritage in the newspaper material arepartly shaped by the media dynamics in the mediatization of religion.
(TIDAK) MENYOAL DEWAN KEAMANAN NASIONAL INDONESIA
Authors: Montratama Ian , Yani Yanyan Mochammad
Published: December 2019

That approach requires a interagencies coordinating forum to break any strategic bureucratic blockades. Such forum is known as National Security Council (NCS). In Indonesia, NCS is not created. This paper tries to analyze the creation of NCS that currently being hampered due to the absence of National Security Law.

 

Keywords: interagencies, coordination forum, National Secuirty Council (NCS)

 

Abstrak

 

Hampir seluruh isu Keamanan Nasional bersifat multi dimensi yang hanya bisa ditangani secara lintas kementerian/lembaga. Hal tersebut menuntut adanya forum koordinasi lintas kementerian/lembaga agar hambatan terkait birokrasi yang bersifat strategis dapat diterabas. Forum seperti itu dikenal dengan Dewan Keamanan Nasional (DKN). Di Indonesia, DKN belum terbentuk. Naskah ini berusaha mengkaji pembentukan DKN yang saat ini terkendala dengan absennya UU Keamanan Nasional.

 

Kata Kunci: lintas kementerian/lembaga, forum koordinasi, Dewan Keamanan Nasional (DKN)
TIONGKOK SEBAGAI PEMIMPIN DUNIA BARU MELALUI INVESTASI DI NEGARA-NEGARA DI DUNIA
Authors: Nadya Annissa , Trihandayani Elshadai , Usha I Gusti , Agnetha Maria , Soukotta Theofilia , Melani Sepril
Published: December 2019

Tulisan ini akan membahas mengenai Tiongkok sebagai negara yang saat ini dapat dikatakan sebagai negara superpower. Tiongkok melakukan investasi global besar-besaran dan hadir di negara-negara di seluruh dunia, tidak terbatas hadir di negara-negara berkembang tetapi juga di negara maju.Investasi Tiongkok yang hampir hadir di sebagia besar negara di dunia, menunjukkan Tiongkok telah berhasil memperluas pengaruhnya, sehingga semakin besar kekuatan yang dimiliki Tiongkok. Kemudian, inovasi besar yang digagas oleh Tiongkok, mendorong semakin banyak hadirnya investasi Tiongkok di dunia.Seluruh kawasan telah  merasakan hadirnya Tiongkok dengan adanya investasi tersebut. Tiongkok dipandang sebagai negara yang penting saat ini.Adapun tujuan tulisan ini adalah untuk menjelaskan bagaimana investasi global yang dilakukan Tiongkok, mendorongnya hadir sebagai pemimpin dunia saat ini. Metode penelitian ini bersifat kualitatif.Penulis menggunakan teori World Leadership menurut Modelski sebagai pedoman.Tulisan ini menemukan, jika Tiongkok berpotensi untuk menjadi New World Leader berlandaskan kekuatan dan inovasi yang dimiliki Tiongkok.

 

Kata Kunci : Tiongkok, Investasi, New World Leader, Kekuatan
RIVALITAS GEOPOLITIK AMERIKA SERIKAT â€“ TIONGKOK DI MYANMAR
Authors: Suwarman Eufronius , Watunwotuk Kartika , Melianti Lecya , Rosari Maria , Yewen Natalia , Naomi Regina
Published: December 2019

Kompetisi komprehensif A.S.-China saat ini bermain dalam skala yang semakin global. Fokus utama kompetisi adalah wilayah Indo-Asia-Pasifik yang luas, dan berpusat di Asia Tenggara, contohnya adalah Myanmar.  Penulisan ini akan membahas rivalitas AS dan Tiongkok di Myanmar untuk mencapai kepentingan nasional mereka. Metode yang digunakan dalam penulisan ini adalah metode kualitatif. Argumen akhir dari penulisan ini bahwa rivalitas AS-Tiongkok ditujukan untuk memperluas pengaruh mereka di Myanmar karena wilayah Myanmar yang strategis dan sumber daya alam yang melimpah menjadi daya tarik Tiongkok. Keuntungan Beijing sebagian besar ekonomi dan diplomatik, sedangkan Washington lebih beragam. Namun Myanmar mampu menyikapi dengan baik kehadiran dua kekuatan besar tersebut.

 

Kata Kunci: Rivalitas AS-Tiongkok, Kepentingan nasional AS-Tiongkok, Respon Myanmar
GEOPOLITIK CINA DAN JEPANG DI ASIA TIMUR: SENGKETA KEPULAUAN DIAOYU/SENKAKU
Authors: Christianty Destrina , Jonathan Geriel , Simamora Lamtiur , Helena Ribka , Rebecca Ruth Diana , Wacanno Sathya Reysha
Published: December 2019

Pulau-pulau tak berpenghuni yang dikenal sebagai Senkaku untuk Jepang dan Diaoyu untuk Cina terletak sekitar170 km dari Okinawa dan Taiwan, dan 380 km dari daratan Cina. Kedua pihak saling mengklaim kepemilikandari pulau tersebut, berdasarkan pada bukti sejarah dan perjanjian. Namun, perbedaan interpretasi bukti sejarahdan perjanjian menjadikan perselisihan antara Cina dan Jepang tentang hak kepemilikan dari pula tersebut. Posisipulau yang sangat strategis di Samudera Pasifik dan pada tahun 1969 AS mengungkapkan, bahwa pulau-pulauitu mungkin memiliki cadangan minyak dan gas yang membuat Republik Rakyat Tiongkok mengklaim pulau-pulau itu hanya dua tahun kemudian. Kedua hal tersebut mempersulit dalam pencapaian kesepakatan dalam halkepemilikan dari pulau tersebut.
Study of susceptibility of pathogenic flora to various antiseptics in multi-field hospital
Authors: Rusanova P. A. , Dubel E. V.
Published: December 2019

Antiseptics are an effective method of fighting infections associated with the provision of medical care, are widely used for the treatment and prevention of a number of diseases. The antimicrobial activity of antiseptics used in a multi-field hospital has been studied.
Quality management system of medical care in medical organization
Authors: Melik-Guseinov D. V. , Emanuel V. , Khodyreva L. A. , Turzin P. S. , Emanuel A.
Published: December 2019

The problem of assessing and improving the quality of medical care in a medical organization is considered. Analyzed the management of medical organization processes. A scheme for managing these processes, a list of regulatory documents, types and methods for monitoring the effectiveness of their implementation are presented. Formed groups of criteria used to assess the quality of the medical organization. It is argued that the introduction of a quality management system for the provision of medical care in a medical organization increases the efficiency of its activities.
Case of successful treatment of second-degree AV block in patient with gastroesophageal reflux disease associated with hiatal hernia
Authors: Fedulaev Yu. N. , Makarova I. V. , Pinchuk T. V. , Lukanin D. V. , Sokolov A. A. , Klimenko M. S. , Sokolov A. A. , Lukanina A. A.
Published: December 2019

Clinical observation of a young patient without an organic pathology of the heart, who repeatedly sought medical help in connection with complaints of episodes of dizziness, lability of blood pressure and pulse numbers, is presented. The medical survey revealed a link between clinical symptoms and progressive retardation of AV conduction (from first-degree AV block to second-degree Mobitz II), and therefore the patient was recommended to be implanted with permanent artificial cardiac pacemaker. To clarify the nature of the conduction disorders, an invasive electrophysiology study was performed, which revealed a proximal AV block due to vagal influences. As the most likely cause of stimulation n. vagus was considered identified in a patient gastroesophageal reflux disease associated with hiatal hernia. Surgical treatment (laparoscopic fundoplication) led to a regression of the clinical and electrocardiographic picture, avoiding the implantation of permanent artificial cardiac pacemaker. The tactic chosen is consistent with the algorithm for managing patients with AV conduction abnormalities (2018 ACC / AHA / HRS Guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay), which involves eliminating potentially reversible causes of bradyarrhythmia before deciding whether to install permanent artificial cardiac pacemaker.
Spondyloarthritis: management algorithms and experience of target therapy
Authors: Babaeva A. R. , Kalinina E. V. , Zvonorenko M. S. , Shcherbinina E. V. , Bramnik I. V.
Published: December 2019

The article presents current data on algorithms for managing patients with the most common forms of spondylarthritis — ankylosing spondylitis, axial spondylarthritis and psoriatic arthritis, based on existing national and European recommendations. The analysis of innovative approaches to the patho‑genetic therapy of spondyloarthritis with special attention to the inhibition of interleukin‑17 using the drug secukinumab. Along with the literature data, there is a clinical experience of using secukinumab in patients with ankylosing spondylitis, axial spondyloarthritis, and psoriatic arthritis. It has been shown that secukinumab can improve the quality of treatment and achieve clinical remission in patients with high disease activity and adverse prognostic factors. In connection with the high efficacy and safety of treatment, the feasibility of using secukinumab as a first‑line biological agent with insufficient response to a standard basic drug is discussed.
Importance of clinical methods of diagnostics of early inflammatory changes developing in tissue of periimplantate zone beside somatic patients
Authors: Ashurov G. G. , Mullodzhanov G. E. , Ismoilov A. A. , Amkhadov I. S. , Muzaeva Z. R.
Published: December 2019

Early diagnostics of the inflammatory changes in soft tissue of surrounding innerbone dental implants under disadvantage somatic background, promotes well-timed undertaking necessary hygienic and medical action of implantological nature, which the primary task is a warning the further spreading the inflammatory process in subjecting to bone fabrics, from condition which depends not only period of the operation implant’s themselves, but also installed on them prosthetic design.
Influence of psychoemotional stress on microbal landscape of gingival furrow
Authors: Risovannaya O. N. , Lalieva Z. V.
Published: December 2019

Relevance of the research topic. The oral cavity is one of the most diverse microbiomes in the human body, which is divided into several biotopes: oral mucosa, dental plaque, gingival fluid and gingival sulcus zone and others. The biotope of the gingival sulcus is unique in that quantitative and qualitative changes in the microbial communities of this microecological system can lead to the development of the main dental diseases —   gingivitis, periodontitis and caries. Purpose. To study the influence of emotional stress on the microbal landscape of the gingival furrow, which is in a state of eubiosis and dysbiosis. Materials and methods. The study involved 67 aged by 30–49 years. A microbiological study was made of the general microbial contamination of the gingival furrow and its colonization by individual microbal species using aerobic and anaerobic cultivation methods. Results. In the state of relative dormancy, 100 % of people without gum disease were found to have an eubiotic condition of the gingival microbal, at 100 % of persons with periodontis the microbal of the gingival groove was in a state of dysbiosis. Summary. The influence of the stressor on the disorder of the balance of the microbial homeostasis of the dental gingival slit causes an increase in the imbalance of microbial associations in the form of a decrease in the comensal microflora and an increase in the opportunistic pathogenicity. Highlights. 1. Emotional stress may cause the development of periodontal diseases in people who work in the field of law enforcement. 2. On a background of emotional stress the dysbalance of microbial associations increases.
Clinical and endoscopic features of gastroesophageal reflux disease in patients with obesity
Authors: Sirchak Ye. S. , Stan M. P. , Pichkar Yo. I. , Sirchak S. S.
Published: December 2019

Clinical and endoscopic results of a study at 94 patients with gastroesophageal reflux disease (GERD) and obesity, as well as 85 patients with GERD are presented. A high incidence of atypical clinical manifestations of GERD on the background of obesity (an extraesophageal form of the disease) was revealed. An endoscopic study has mainly established reflux esophagitis of grades B and C (LA) in patients with obesity and a high percentage of cases (up to 59.5%) of duodenogastric reflux with a combination of GERD and obesity, especially in patients with atypical clinical form of reflux disease.
Modern views on development mechanisms and tactics for treatment of patients with gallbladder disease associated with metabolic syndrome
Authors: Akhmedov V. A. , Gaus O. V.
Published: December 2019

The high prevalence of metabolic syndrome in population has led to the cholelithiasis is important problem of modern health care along with coronary heart disease, arterial hypertension and diabetes. The main role in the formation of gallbladder pathology in patients with metabolic syndrome belongs to insulin resistance, atherogenic dyslipidemia, and non‑alcoholic fatty liver disease. Тhe prescription of ursodeoxycholic acid is pathogenetically justified. This article presents modern views on the mechanisms formation of gallstone disease in the conditions of metabolic disorders and management of this patients based on the results own research.
Individualization of Drug Therapy Mode in a Patient with Disseminated Form of GIST by Determining Active Metabolites of the Drug (Tyrosine Kinase Inhibitor) in Blood Plasma
Authors: Adleyba S. T. , Kogonia L. M. , Gurevich L. E. , Sidorov A. V.
Published: December 2019

An own experience of effective treatment of a patient with a disseminated form of gastrointestinal stromal tumor (GIST) with a preparation from the group of tyrosine kinase inhibitors (imatinib) is presented.

Relevance. Therapy of gastrointestinal stromal tumors is still a complex problem of modern oncology. Since 2001, a breakthrough has occurred in the treatment of patients with GISTO due to the successful use of a targeted drug from the group of tyrosine kinase inhibitors — imatinib, which is effective in the first line of inoperable and / or metastatic GISTs, and is also used for the neoadjuvant, adjuvant therapy of localized GISTs. The lack of response to therapy and, consequently, the progression of the disease, may be associated with a decrease in the therapeutic concentration of imatinib in the blood plasma. Determining the concentration of active metabolites of imatinib in the serum allows timely identification of potential causes of insufficient response to therapy and individual correction of the dose of the drug.

Materials and methods. In order to determine the significance of the correlation between increasing / decreasing the dose of imatinib and achieving a therapeutic response, we used a laboratory method of high performance liquid chromatography to determine the concentration of imatinib in serum.

Conclusion. Determination of the reduced concentration of active metabolites of imatinib in the blood plasma by high performance liquid chromatography with the detection of tandem mass spectrometry in a patient with disseminated form of GIST allowed to correct the dose of the drug and achieve a positive effect.
Prognostic Impact of Immunohistochemical and Molecular Features of Diffuse Large B-cell Lymphoma
Authors: Kharchenko E. V. , Artemyeva A. S. , Polyatskin I. L. , Semiglazova T. Yu.
Published: December 2019

Diffuse large B-cell lymphoma is the most common type of non-Hodgkin’s lymphoma. Despite of dramatic improvement during last decades in rituximab-era, 30 % of patients are still resistant to initial therapy. Molecular genetics made significant contribution in our understanding of pathogenesis of disease, genetic and epigenetic disorders which have direct impact on cell’s growth, differentiation and immune response. This allowed distinguishing more aggressive subtypes of diffuse large B-cell lymphoma, which can potentially benefit from early-treatment intensification. In this review, we will discuss immunohistochemical and molecular features of diffuse large B-cell lymphoma and its impact on course, prognosis and response to therapy.
Assessment of anxiety-depressive disorders and quality of life indicators in elderly women
Authors: Pavlova T. V. , Proshchayev K. I. , Satardinova E. E. , Pilkevich N. B. , Pavlova L. A.
Published: December 2019

Objective. To assess anxiety-depressive disorders and indicators of quality of life in elderly women.

Materials and methods. The study included 540 women with hormonal disorders in the form of a premenopausal or menopausal syndrome: 270 women, aged 44–54 years (mean age 49.1 ± 2.2), of whom 150 women with ‘–’ and 120 with ‘+’ variant of the biological age and 270 women aged 55–64 years (mean age 57.2 ± 2.4), of which 150 with ‘–‘ and 120 people with ‘+’ version of biological age. All patients, depending on the proposed variant of nutritional support and physical activity, were divided into three groups: the 1st (standard recommendations), the 2nd (standard recommendations, scandinavian walking and daily walks for at least 30 minutes), the 3rd (standard recommendations, scandinavian walking, daily walks for at least 30 minutes and nutritional support). Assessment of the degree of depression was carried out on the basis of the Beck scale. The quality of life was determined by the SF-36 Health Status Survey, a visual analogue scale for assessing the anxiety-depressive syndrome.

Results. On the scale of assessing the level of depression, the level of anxiety-depressive syndrome in women, data were obtained on a reliable improvement of this indicator with the use of nutritional support and physical activity. The maximum difference was noted in older persons with ‘–‘ and ‘+’ variant of biological age. On the scale of assessing the level of psychological health in women, we obtained data on improving this indicator with nutritional support and physical activity, but a significant difference was found only in comparison with patients who received neither nutritional support nor physical activity.

Conclusion. The use of nutritional support and physical activity in elderly women improves the parameters of quality of life, especially in terms of general health, depression and social functioning.
Use of mobile applications assessing motor activity of patients after myocardial infarction for improving indicators of physical rehabilitation
Authors: Ponkin S. L. , Tsygankova O. V. , Fyodorova E. L. , Bondareva Z. G.
Published: December 2019

Considering the widespread use of mobile phones, cellular communication systems wide coverage of the territory of the Russian Federation, the free or low cost of mobile applications for assessing motor activity, convenient interface and high accuracy of measurements of the apps; the usage of the modern technologies while involving underwent myocardial infarction patients into rehabilitation programs could increase the percentage of these programs participants and improve the results obtained during the implementation of the programs.

Research goal. assessment of the impact of the usage of mobile applications, that could monitor the level of motor activity, on the results of a six-minute walk test (6 MWT) among the patients with myocardial infarction who were on the second stage of cardiac rehabilitation.

Materials and methods. Materials and methods: 224 patients were examined: 99 (44.2 %) men and 125 (55.8 %) women aged 60.6 ± 11.5 years, who had had myocardial infarction from 6 days to 6 months ago (median 16 [10; 139] days), which passed the second stage of rehabilitation for 11.6 ± 1.4 days in the conditions of the specialized cardiology department of the Resort-hotel ‘Sosnovka’ (Berdsk, Russia). At the time of admission, in the middle of the rehabilitation course (on the 6th day) and before discharge (on the 12th day), a six-minute walk (6 MWT) test was performed (6 MWT1, 6 MWT2 and 6 MWT3, respectively). Changes in these parameters over time were estimated as the difference between the second and first 6 MWT, the third and first 6 MWT test results, and compared in two groups.

Results obtained. The results of 6 MWT1 performed on admission of patients to the department did not differ between the two groups (F = 3.068; p = 0.81). 6 MWT2, conducted on average one week after the start of the second stage of the cardio-rehabilitation program revealed a statistically significant difference between the groups (F = 21.758; p < 0.001), which became more visible when 6 MWT3 was conducted at the end of the second week in the department (F = 66.615; p < 0.001), indicating the advantages of the group using the mobile application.

Conclusion. The active introduction of mobile applications into real clinical practice effectively, non-invasively, does not require additional financial investments from the health care system and personal time of the doctor, being a positive determinant of the preventive behavior of patients.
Combined use of micro-focused ultrasound and autologous blood cells in correction of involutive skin changes
Authors: Yusova Zh. Yu. , Stepanova T. V. , Belkov P. A.
Published: December 2019

A comparative study of micro-focused ultrasound in monotherapy and combined use with autologous blood cells was conducted. In assessing the effectiveness of the procedures studied the qualitative characteristics of the skin and ultrasound scanning data. All patients (35) with involutional changes of the skin at the procedures were divided into tho groups: combined application of ultrasound macrofocusrange with autologous red blood cells and macrofocusrange ultrasound as monotherapy. The results of the study, data were obtained that showed a more pronounced clinical effect in patients treated with the combined use of ultrasound macrofocusrange with autologous red blood cells.
Undifferentiated connective tissue dysplasia in dermatological and cosmetological practice (clinical case)
Authors: Ikonnikova E. V. , Stenko A. G. , Kruglova L. S.
Published: December 2019

The article presents a case of clinical observation of a patient with connective tissue dysplasia. This pathology, as a result of various genetic disorders, includes an extensive group of different systemic conditions, most of which have certain dermatological pathologies as the main or concomitant symptom. We describe the questions of etiology, clinic and diagnosis of connective tissue dysplasia. This clinical case is interesting to practicing dermatologists and cosmetologists in connection with the high appeal of this category of patients for aesthetic help.
Dermatoscopy in diagnosis of infectious and parasitic skin diseases
Authors: Sergeev Yu. Yu. , Sergeev V. Yu.
Published: December 2019

Entodermoscopy is one of the trends in dermatoscopic diagnosis of skin diseases, which describes specific signs of infectious and parasitic dermatoses. Current article presents a description and illustrations of the most common forms of fungal infection, including tinea capitis, herpes zoster, tuberculosis, leishmaniasis and tungiasis. Dermatoscopic examination is proposed to be used as an additional tool for evaluating the effectiveness of the therapy, allowing to control the restoration of the skin structure and its appendages in the treatment process more precisely.
Role of stress in development of cardiovascular pathology in extreme professions
Authors: Orlova N. V. , Starokozheva A. Ya. , Timoshchenko A. V.
Published: December 2019

Psychoemotional stress is a risk factor for cardiovascular diseases, including arterial hypertension and coronary heart disease. Neurohumoral mechanisms are involved in the development of hypertensive reactions to stress. The severity of stress reactions depends on the stress resistance of people. The study of stress resistance is carried out in industrial sectors associated with the impact of professional psycho-emotional stress. Studies in locomotive drivers reveal a high level of cardiovascular disease. Stress helps to reduce vitamin D. Vitamin D deficiency helps reduce stress resistance. Studies conducted among locomotive drivers have revealed a high prevalence of vitamin D deficiency, requiring medical correction.
Clinical case of lupus pneumonitis complicated by bilateral polysegmental pneumonia in patient with systemic lupus erythematosus
Authors: Fedulaev Yu. N. , Chuprakova A. Yu. , Kaminer D. D. , Savina D. V.
Published: December 2019

The article discusses the clinic, the main systemic manifestations, diagnostic methods for systemic lupus erythematosus. The given clinical case demonstrates the difficulty of managing a patient with pneumonia and systemic lupus erythematosus (SLE). The use of glucocorticosteroids in patients with SLE with developed pneumonia is discussed.
Abstracts of scientific and practical conference ‘Topical issues organization of emergency, including emergency specialized medical care’
Authors: Editorial Article
Published: December 2019

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Features of hematopoiesis in newborns with signs of morphofunctional immaturity
Authors: Baranovskaya I. B. , Samokhina O. F. , Boyko N. V. , Sysoeva I. P.
Published: December 2019

The purpose of this work was to identify the characteristics of hematopoiesis in newborns of 1–7th days of life with signs of morphofunctional immaturity. Three groups of newborns were formed: 1) healthy full-term babies (control); 2) full-term, but low-weight for gestational age children; 3) premature babies (gestational age 34–36 weeks) with signs of malnutrition. On the Sysmex XN analyzer, traditional hemogram indicators were analyzed, including reticulocyte parameters, as well as a calculated index —  an indicator of erythropoiesis (EE) effectiveness. A total of 714 blood samples were examined. The following statistical characteristics of the indicators were analyzed: mean value (M), mean standard square deviation (Sd), error of the mean value (St er). The statistical significance of intergroup differences was established on the basis of the Money-Whitney test (p ≤ 0.05). Comparative intergroup analysis showed no statistically significant differences (p ≥ 0.05) between the baseline red blood values (hemoglobin, erythrocytes, hematocrit, etc.) in the control newborns and children with signs of morphofunctional immaturity. According to the data obtained in newborns in the full-term, but low-weight for gestational age (group 2), there was a tendency to a decrease in the content of reticulocytes and their immature fractions, an indicator of the erythropoiesis efficiency, an index of reticulocyte production. Premature infants with signs of malnutrition (group 3) differed from the control group in a statistically significant (p ≤ 0.05) increase in the content of reticulocytes (by 2–3 days), an index of their production (by 2 days), and also an indicator of erythropoiesis (on 2–3 days). At the same time, a statistically significant decrease in the content of leukocytes (1st and 4th days), neutrophils (4th day) and lymphocytes (3rd day) was registered in premature babies.