bluuebunny/crossref_metadata_2025 huggingface dataset:
ASSESSMENT OF BIOFUEL PRODUCTION TECHNOLOGIES FROM MICROALGAE AND ORGANIC WASTE
Authors: Pavliukh Lesia , Lialuk Natalia , Horbachova Olena
Published: September 2022

Today, the processing of organic matter, such as organic waste or microalgae, is an important way to renewable energy sources. To maintain a prosperous life of the population, it is critical that renewable sources of energy be found. Problem statement. In the near future, mineral and organic reserves of the earth's interior will cease to meet the growing energy needs of civilization.  Already today, technologies have emerged that allow the production of fossil fuels based on many plant species.  But the cultivation of such crops leads to depletion of land resources.  In other words, the top and thin fertile layer of humus is gradually depleted, which can lead to the use of millions or billions of hectares of arable land.  And here to replace usual terrestrial cultures come microalgae.  Research methodology.  The study was based on the analysis of theoretical studies and comparison of different types of biological fuels from plant-type and microalgae, at the economic, environmental and social levels.  Results and discussion.  Biodiesel from microalgae is a third generation fuel obtained by processing vegetable raw materials.  It is known that algae are characterized by a high content of fatty acids, which are the basis for the production of biodiesel. Microalgae are very cheap and, at the same time - highly productive raw materials.  One hectare of microalgae produces 30 times more biofuel than one hectare of soybeans.  At the same time, biofuel from algae is 5-10% more energy-intensive than biodiesel from vegetable oils.  In addition, microalgae grow quite rapidly.  For example, algae, which is 80% composed of substances similar in origin to oil, grows in 10 days, while the same algae, which is 30% composed of substances similar in origin to oil, grows in only 3 days.  Another advantage of using algae is the fact that, unlike growing other types of plant materials, they do not need to be fed and fertilized - they use carbon dioxide (CO2) for growth.  The higher the concentration of carbon dioxide, the faster they are cultivated.  Thus, the cultivation of microalgae can solve several problems: the problem of the greenhouse effect;  the problem of employment of sown areas;  the problem of shortages of traditional fuels and many other equally important problems.  Conclusion. Organic susstance as microalgae have been experimented as a potential feedstock for biofuel generation in current era owing to its’ rich energy content, inflated growth rate, inexpensive culture approaches, the notable capacity of CO2 fixation, and O2 addition to the environment. The implementation of the technology of biofuel production from organic waste also warns of danger, first of all for people. By reducing free waste, use it as a secondary material and benefit from it. Integrated waste management technology includes successive steps that take into account the environmental, economic and social spheres of life.
Effectiveness of Palliative Care Workers in Patient Nutrition
Authors: KESER Murat , GÖK BALCI Umut , YAVUZŞEN Tuğba , UNAL Olcun Umit
Published: September 2022

Objective:It is important to evaluate the nutrition of patients in palliative care centers. Most patients are unrecognized and lacking treatment, as there is no consensus on ways to scan, diagnose, treat and follow the malnutrition, and the lack of adequate awareness and training of healthcare professionals. This study aims to evaluate the approaches and awareness of healthcare professionals in Turkey who support nutrition in Palliative Care Centers.

Material Method: A survey, prepared by researchers, conducted to assess the effectiveness of healthcare professionals in patient nutrition, was conducted on a virtual basis in all healthcare professionals who were fully employed, accessible and volunteered with palliative care patients. The data was evaluated through descriptive and analyzing statistical methods.

Findings: The average age of the 105 medical professionals who participated in our study was 36.4±9.3 (25-59), of whom 68 (64.8%) were women and 37 (35.2%) were men. Sixty-seven (63.8%) of the participants, most of whom were physicians, were specialists, 30 (28.6%) were assistants and general practitioners, and 8 (7.6%) were nurses. When asked how many of their patients they started feding products, 38 people (36.2%) said, with 41-60%. If you think you've got enough recognition of nutritional content, there were 28 people who said yes (26.7%), 30 people who said no (28.6%), and 47 people (44.8%) who said sometimes. When asked what they considered the most when planning a feeding product, 95 people (90.5%) said that they cared about the patient's request, compared to the calories and content of the product.

Discussion: Our study found that participants were largely absent from knowledge and awareness, and observed differences in patient attitudes. Most participants require neutral education and continuity in order to have awareness.
Quadruple Therapy in Patients with Immune Thrombocytopenia
Authors: ASLANER AK Müzeyyen , SAHİP Birsen
Published: September 2022

Objective:In the treatment of immune thrombocytopenia dexamethasone, rituximab, and cyclosporine combination therapies provided promising results in recent years. This study aimed to investigate the responses of patients with quadruple therapy which created by combining combinational therapies given in immune thrombocytopenia with eltrombopag.

Method: Four patients diagnosed with immune thrombocytopenia who received steroid in the first-line treatment and eltrombopag in the second-line treatment without achieving complete remission/partial remission were retrospectively evaluated in terms of the treatment they received and response rates.

Result:Patients with relapsed/refractory immune thrombocytopenia were treated by oral dexamethasone, oral cyclosporine and intravenous low-dose rituximab in addition to eltrombopag therapy. Eltrombopag treatment was continued at a dose of 50mg/day. No loading dose was given for cyclosporine, weekly blood cyclosporine level was monitored for toxicity and the treatment was titrated to a target dose of 200 to 400 μg/L. No toxicity-induced death, serious treatment-related adverse events, or non-adherence to treatment were observed. The 6-month response rate was 75% and the treatment was well tolerated. Two patients were still followed up by us with a complete response, while one our patient underwent splenectomy because of relapse after 6 months and is still being followed up with eltrombopag therapy. In one our patient, which was unresponsive, romiplastim treatment was applied but there was no response to this treatment either. The patient was referred to a clinical study

Conclusion: Our study showing that a combination of quadruple therapy can be a treatment option in patients with treatment-resistant immune thrombocytopenia is promising.
Reflection of Significant Theological Issues in the Lavra School Paintings of the First Third of the Eighteenth Century
Authors: Kondratiuk Alina
Published: September 2022

The article discusses the most significant monumental paintings of the Dormition Cathedral and Trinity Gate Church of Kyiv-Pechersk Lavra created in the first third of the 18th century. They are сonsidered in the context of the most important trends of spiritual and cultural life of the Hetmanate. The author concentrates attention on the important details that characterize the system of painting in those temples and underlines the close connection between fresco images marked by the inscriptions with the church literature of that time. Besides, among the results of the research there is the point that the Holy Liturgy is the most significant theme in the theological program of paintings of both Lavra temples.It is noted that the topic of the Holy Liturgy became one of the central themes in Ukrainian theology of the second half of the 17th century. Sharp disputes between Kyiv and Moscow theological circles were concentrated on the very moment of the Holy Liturgy associated with Eucharistic Transubstantiation. The author mentions publications of the Ukrainian Orthodox printing houses of that time, which covered that issue, and underlines a number of discrepancies in other dogmatic moments found in Kyiv and Moscow publications.Lavra school monumental ensembles of the first third of the 18th century are presented as a reflection of this topic. We believe that the idea of a figurative display of the liturgical ceremony on the walls of the altar first appeared in the paintings of the Dormition Cathedral of Kyiv-Pechersk Lavra. Thus, the way was paved for the topic that has become traditional and lasted like that over the century. The analysis of the preserved project of baroque paintings of the Great Church, available images of the Trinity Gate Church, and inscriptions makes it possible to say that the ideological and artistic content of Lavra school monumental paintings of the first third of the 18th century reflected the most relevant ideas of that time. Among them one could mention sharp theological disputes over the moment of Eucharistic Transubstantiation that typified the second half of the 17th century.
Pietrzkiewicz, Iwona. Kultura książki w zakonach męskich Wielkiego Księstwa Litewskiego XV–XVIII wieku (Kraków: Wydawnictwo Naukowe Uniwersytetu Pedagogicznego, 2019), 447 s.
Authors: Tupytsia Mykhailo
Published: September 2022

Pietrzkiewicz, Iwona. Kultura książki w zakonach męskich Wielkiego Księstwa Litewskiego XV–XVIII wieku (Kraków: Wydawnictwo Naukowe Uniwersytetu Pedagogicznego, 2019), 447 s.
Constructing a Hoop Using Rough Filters
Authors: Borzooei Rajab Ali , Babaei Elham
Published: September 2022

When it comes to making decisions in vague problems, rough is one of the best tools to help analyzers. So based on rough and hoop concepts, two kinds of approximations (Lower and Upper) for filters in hoops are defined, and then some properties of them are investigated by us. We prove that these approximations- lower and upper- are interior and closure operators, respectively. Also after defining a hyper operation in hoops, we show that by using this hyper operation, set of all rough filters is monoid. For more study, we define the implicative operation on the set of all rough filters and prove that this set with implication and intersection is made a hoop.
Ludyczność w (glotto)dydaktyce – stan badań i rozwój metody
Authors: Kaźmierczak Paulina , Banach Agnieszka
Published: September 2022

Artykuł składa się z dwóch części. Pierwsza z nich prezentuje dotychczasowe badania dotyczące ludyczności w nauczaniu m.in. języków obcych. Przedstawia zalety i wady wykorzystywania metody ludycznej, która staje się coraz bardziej popularna we współczesnej dydaktyce. Druga część zawiera opisy poszczególnych artykułów znajdujących się w tomie, a tym samym pozwala na zapoznanie się z treścią niniejszej publikacji.
Elementy ludyczne w kształceniu lektorów języka polskiego jako obcego
Authors: Kaźmierczak Paulina
Published: September 2022

Artykuł wyjaśnia zasadność wprowadzania elementów ludycznych w procesie kształcenia lektorów języka polskiego jako obcego. Ponadto prezentuje przykładowe zajęcia prowadzone z zastosowaniem metod ludycznych. Ich tematyka obejmuje: zajęcia wstępne, internet w pracy lektora, lekcje dla dzieci i młodzieży oraz umiejętność adaptacji gier i zabaw na potrzeby zajęć językowych. Przeprowadzone zajęcia pozwalają na wskazanie podstawowych zalet i wad pracy ze studentami w oparciu o metody ludyczne.
Konkurs „Recensiamo ItaliAMO” – o współzawodnictwie zachęcającym do nauki języka i poszukiwań literaturoznawczych
Authors: Groblińska Justyna , Kowalik Katarzyna
Published: September 2022

Zawarte w artykule obserwacje na temat kreatywnych form nauczania języka obcego i literatury opierają się na doświadczeniach zebranych podczas organizacji na Uniwersytecie Łódzkim w 2018 i 2019 r. dwóch edycji konkursu „Recensiamo ItaliAMO”, polegającego na tworzeniu przez studentów recenzji włoskich dzieł literackich opublikowanych po roku 2000. Pierwsza część przedstawia dydaktyczne motywacje, które skłoniły nas do zaproponowania studentom filologii włoskiej takiej formy ponadobowiązkowej aktywności oraz opis zasad uczestnictwa. Późniejsza analiza zgromadzonego dzięki wydarzeniu materiału pozwala poznać wybory czytelnicze studentów oraz ocenić ich pozytywną rolę w procesie dydaktycznym i poszerzaniu kompetencji kulturowych. Daje również podstawy do zauważenia pewnych negatywnych zjawisk, takich jak kłopoty studentów neofilologii ze stworzeniem poprawnego pod względem językowym tekstu czy brak umiejętności dostosowania się do założeń gatunkowych recenzji. Wszystkie te aspekty dostarczają cennej wiedzy, którą może posłużyć do planowania zajęć z praktycznej nauki języka i literatury w kolejnych latach pracy dydaktycznej.
Elementy ludyczne w nauczaniu związków frazeologicznych – analiza wyników ankiety przeprowadzonej wśród studentów romanistyki
Authors: Świątek Zuzanna
Published: September 2022

Należy zauważyć, iż związki frazeologiczne są z reguły trudne do zapamiętania, dlatego tak ważne jest dobranie odpowiednich metod nauczania przez nauczyciela. W nauczaniu frazeologizmów wykorzystanie strategii ludycznej powinno być istotnym elementem na lekcjach języka obcego, bez względu na grupę wiekową, aby przyspieszyć proces uczenia się. Celem niniejszego artykułu jest zbadanie, jaki poziom wiedzy posiadają studenci filologii romańskiej z zakresu frazeologii języka francuskiego oraz znajomości technik szybkiego zapamiętywania, bardzo często wykorzystywanych w strategii ludycznej. Wprowadzenie technik pamięciowych w trakcie zajęć przyczynia się zarówno do trwalszego zapamiętania danego frazeologizmu, jak i rozwoju kreatywności ucznia. Nauka poprzez zabawę zachęca studentów także do aktywnego uczestnictwa w lekcjach, co przekłada się na efekty dydaktyczne. W trakcie przeprowadzonego badania sprawdzono poziom znajomości wybranych frazeologizmów oraz technik samodzielnego uczenia się wśród studentów romanistyki. Z analizy ankiety wynika, iż studenci nie posiadają wystarczająco dużo wiedzy z zakresu frazeologii języka obcego. Jednakże, większość z nich nie spotkała się z ćwiczeniami opartymi na technikach zapamiętywania. Oprócz dydaktycznego punktu widzenia przedstawiono aspekt językoznawczy, pomagający zrozumieć różnice i podobieństwa między związkami frazeologicznymi.
The Influence Of Letters Of Meanings In Determining The Meaning: An Applied Study of the Verses' Interpretation of the Determining the Fetus Gender Timing in Contemporary Exegeses/ أثر حروف المعاني في توجيه المعنى - دراسة تطبيقية في تفسير آيات توقيت تحديد جنس الجنين في التفاسير المعاصرة
Authors: Burhan Ahmad S , Hajji Abdulaziz E , Asaad Ali M , Nawaya Fehmieh R
Published: September 2022

Teaching the use of letters of meanings is an essential part of teaching the Arabic language, as these letters affect the meaning of speech, and their grammatical and semantic functions are synergistic to determine the meanings. The research aims to clarify the effects of the letters of meanings in determining the meaning by conducting an applied study on the verses that talk about the timing of determining the gender of the fetus in the Holy Qur’an. This topic was chosen for the presence of three verses that talk about it, each containing one of the letters of meaning. Thus, by studying the interpretations said, it is possible to determine the impact of the presence of these tools in the verses on determining their meanings. A complete extrapolation included what was mentioned in the most critical contemporary interpretations of the Holy Qur’an about the interpretation of the verses under study. Since this applied study deals with a topic of empirical science, it was helpful to cite the most important scientific references related to this topic. Both analytical and critical methods were assumed. The results proved the significance of the letters of meanings in determining the meanings and that they are indispensable in text understanding. It seems by specifying the semantics of (if) in the two verses of Surat An-Najm that they talk about the timing of determining the chromosomal sex of the fetus that occurs when the sperm fertilization occurs, while the letters (afterwhile and then) in the verses of Surat Fatir and Surat Qiyamah indicate that the verses talk about the timing of determining the organic sex of the fetus represented by the formation of genitals. By reviewing the textbooks of embryology and obstetrics, it was possible to clarify the accuracy of the meanings given by these letters. It is recommended to give the letters of meanings more attention during the educational process because of their widespread use in the Arabic tongue and their significant impact on the meanings that speech carries and performs
Econometría
Authors: Meza Carvajalino Carlos Arturo
Published: September 2022

A diferencia de los dos libros publicados previamente por el autor: “Econometría fundamental” y “Econometría de series de tiempo” este texto, además de integrar los temas básicos e intermedios en el proceso lógico-empírico, incluye nuevos elementos relacionados con las ciencias de la salud en la medición del riesgo a través de modelos de corte transversal; y profundiza en “el paso a paso” al abordar cada metodología econométrica, con el uso de los respectivos programas econométricos. Por complejo que parezca el modelamiento econométrico, “el paso a paso” facilita a los estudiantes tanto de las ciencias económicas como de otras disciplinas, encontrar el camino más expedito para hallar las respuestas desde la construcción lógica-empírica que ofrece la amalgama entre las ciencias económicas, matemáticas y estadísticas con las cuales se construye el fascinante mundo de la econometría.
Condiciones de infraestructura para el desarrollo rural sostenible en Colombia
Authors: Caicedo Londoño María Alejandra , Ramírez Rodríguez Julio César , Ayala Rojas Luis Efrén , Urazán Bonells Carlos Felipe
Published: September 2022

El desarrollo rural en Colombia requiere de un cambio en su dinámica social y económica; el cual no puede darse sin el acompañamiento de mejoras en la infraestructura. Las condiciones de transporte de carga para la productividad del campo son pieza fundamental. Otro aspecto indispensable para mejorar de calidad de vida rural implica analizar las condiciones en que la población domiciliada en lugares apartados de las redes de servicios se surte de agua y atiende las necesidades de saneamiento básico. Como aporte, el presente libro reúne las experiencias en algunas regiones rurales del país y su respectivo análisis técnico como resultado de un proyecto de investigación enfocado en buscar soluciones que mejoren las condiciones infraestructurales a gran parte de la población rural.
Manual de prácticas para el tamizaje visual
Authors: Rubio-Rincón Gina Sorel
Published: September 2022

La optometría es una profesión muy joven, reconocida como la que atiende lo concerniente al funcionamiento visual y ocular en individuos y poblaciones. De ahí que la enseñanza del tamizaje visual sea el inicio del desarrollo de los conocimientos y capacidades para la atención clínica. Por ello, este libro pretende introducir, de forma práctica y como manual de consulta rápida, un soporte teórico-práctico, para aprender e interiorizar de manera ordenada y adecuada el examen básico que debe realizarse, y con su ejecución lograr diagnósticos adecuados y conductas oportunas.
Ciudadanías, experiencias religiosas y participación política
Authors: Buitrago Peña María del Pilar
Published: September 2022

La obra busca comprender la configuración de las ciudadanías y de la participación política en las siguientes iglesias: Iglesia Carismática Internacional, Iglesia de Dios Ministerial de Jesucristo Internacional, Comunidad Cristiana Pantokrator y Movimiento Político Colombia Justa Libres. En la primera parte del texto analizan los temas, problemas, escuelas, corrientes, autores de la política y la religión desde diversas disciplinas de las ciencias humanas y sociales. Mientras que la segunda parte abarca el trabajo de campo desarrollado con las iglesias seleccionadas para el estudio, de modo que se recuperan la trayectoria, los sistemas de creencias, las prácticas y los rasgos de la participación política en estas.
Resiliencia, sostenibilidad e informalidad
Authors: Cifuentes Ruiz Paula Andrea , Ortiz Bernal Yenni Yolanda
Published: September 2022

Este libro recopila varios capítulos, resultado de investigación de cuatro universidades que integran la Red de Resiliencia y Sostenibilidad, en ellos se reconocen diferentes formas de relacionamiento entre conceptos, formas de entender y prácticas de resiliencia, sostenibilidad e informalidad, evidencia de variadas posturas académicas e investigativas en territorios urbanos y rurales de Colombia. Los capítulos presentan metodologías teórico-prácticas y herramientas de aproximación al territorio en múltiples contextos y escalas variadas en donde la informalidad, tanto en barrios como en regiones, han dado lugar a diversas estrategias que demuestran la capacidad de gestionar mejores condiciones de vida por parte de las comunidades y aportar al desarrollo territorial.
Unpacking ‘Tax Morale’: Distinguishing Between Conditional and Unconditional Views of Tax Compliance
Authors: Prichard Wilson
Published: September 2022

The past decade has witnessed a surge in international interest in the importance of tax morale. This is often defined, broadly, as taxpayer’s ‘non-pecuniary motivations for tax compliance’ (Luttmer and Singhal 2014: 150) – as a key component of strategies for strengthening tax compliance in lower-income countries. Whereas classic models of tax compliance focused on the importance of the threat of enforcement and the cost of compliance in shaping compliance, compliance decisions are also significantly shaped by non-pecuniary motivations. They can, for example, be an intrinsic commitment to paying taxes, expectations of reciprocity from government, or broader social norms. This has been reflected in growing interest in strategies for strengthening tax morale in order to encourage quasi-voluntary tax compliance (Prichard et al. 2019). A significant part of this literature has relied on surveys to measure taxpayer attitudes towards tax compliance (tax morale), and, in turn, to identify factors associated with higher or lower levels of reported tax morale.
Cone Penetration Test characterization of middle and upper Miocene lithostratigraphic units near Antwerp International Airport
Authors: DECKERS Jef , GOOLAERTS Stijn
Published: September 2022

Recently published multidisciplinary studies discussed the glauconiferous sand units of the Berchem and Diest formations in large temporary outcrops near the Antwerp International Airport, east of the City of Antwerp, northern Belgium. At this location, the upper Miocene Diest Formation was subdivided into an upper Deurne Member and a lower, recently introduced, Borsbeek Member. In the current study, Cone Penetration Tests performed near the outcrops were used to geotechnically characterize the exposed units for regional correlations. For the Kiel and Antwerpen members of the middle Miocene Berchem Formation, the geotechnical expressions are nearly identical to those recently described further west in the City of Antwerp area. Contrary to the latter area, however, the upper part of the Antwerpen Member is missing, due to erosion below the Borsbeek Member. This erosion reached up to the level of a regionally occurring, compact shell bed in the middle of the Antwerpen Member, which may have protected the underlying sand from further erosion. Throughout the study area, the Borsbeek and Deurne members each show a consistent geotechnical facies, allowing for them to be distinguished on electric CPTs and thus for more reliable predictions of their areas of occurrence.
Pesquisa Brasileira em Saúde: Análise do Ano de 1990
Authors: Cadoná Eliane , Strey Marlene Neves
Published: September 2022

Neste artigo, colocamos em análise sentidos sobre saúde em produções científicas brasileiras, publicadas no ano de 1990. Tal cenário era marcado pela publicação das Leis Orgânicas da Saúde, cuja emergência se deu em um contexto neoliberal. As bases teóricas do estudo alicerçaram-se no Construcionismo Social. Foram recuperados da BVS Brasil 34 artigos, e a busca se deu por intermédio das palavras-chave “cuidado”, “cura”, “doença”, “política pública de saúde”, “política social”, “saúde” e “saúde pública”. Os dados coletados foram submetidos à Análise de Discurso, resultando na categoria “Importação do conhecimento e comparação entre realidades: o conceito de Brasil Colônia nos discursos da saúde”. Nela, evidenciamos que os discursos produzidos nos estudos carregavam a lógica de que o conhecimento importado, provindo dos chamados países industrializados, deveria ser a regra a ser seguida no Brasil e que a realidade impressa nesses cenários serviria como modelo e inspiração para o país.
Perdas, Luto e Sofrimento Mental em Mulheres no Climatério
Authors: Peixoto Clayton , Ribeiro Tatiana Teixeira de Siqueira Bilemjian , Fernandes Letícia Brito da Mota , Cardoso Adriana , Veras André Barciela
Published: September 2022

Este trabalho tem por objetivo discutir que a maior incidência de adoecimento mental no climatério decorre principalmente das perdas experimentadas nesta etapa da vida. Para cumprir este objetivo, recorremos a uma análise qualitativa de viés psicanalítico, com base na experiência de pesquisadores envolvidos em um estudo transversal, com 130 mulheres climatéricas, com idade entre 45 e 65 anos. As principais queixas observadas foram organizadas em grupos por similaridade temática. Observou-se que, no período do climatério, o luto se instala por diferentes perdas percebidas pelas mulheres. A maioria dessas perdas está relacionada a questões de estética, de fertilidade, projeto de vida e as perdas sociais vivenciadas. Concluímos que o adoecimento mental observado no climatério pode ser o sintoma que se forma para denunciar um contexto de perdas. A compreensão dessas perdas e da instalação de um processo de luto pode permitir um olhar mais humano e cuidado mais eficiente.
Objetalização no Hospital e os Tempos de Covid: Uma Elaboração Psicanalítica de Experiências
Authors: Alberti Sonia , Silva Heloene Ferreira da , Diniz Andressa Pinto , Moraes Luisa Freire de , Soares Luiza da Cunha , Dantas Priscila Mählmann Muniz
Published: September 2022

Visou-se identificar, a partir da teoria psicanalítica, questões advindas da clínica institucional em um hospital universitário no contexto da covid-19. Os pontos abordados no presente trabalho levaram-nos a elaborar teoricamente um sintoma institucional: a objetalização. Tal conceito já foi utilizado por diversos autores e diz respeito à destituição do sujeito que, nos mais diferentes contextos, pode vir a ser tomado como objeto não apenas das práticas, mas também nos discursos. Levantamos a hipótese de que os efeitos da pandemia vivida em 2020, que assolou o hospital em que atuamos, escancarou a objetalização não apenas dos pacientes e de suas famílias, mas também das equipes, que, em sua maioria, procuraram esmerar-se sobremaneira para fazer frente à conjuntura. Desse modo, sustentamos que a objetalização, que vimos a olhos nus no contexto da pandemia, já estava latente na prática hospitalar, mesmo em tempos menos sombrios.
Percepção da Equipe de Saúde sobre a Implantação de Alojamento Conjunto Mãe-Bebê em Unidade Psiquiátrica
Authors: Artmann Marcelo , Smeha Luciane Najar , Lima Suzinara Beatriz Soares de
Published: September 2022

O alojamento conjunto mãe/bebê em unidade psiquiátrica é uma alternativa para proteger o vínculo e manter os cuidados parentais. O objetivo deste estudo foi conhecer o posicionamento, as sugestões e as necessidades dos profissionais diante da implantação de um alojamento conjunto mãe-bebê. Trata-se de uma pesquisa qualitativa, com 28 profissionais da equipe de saúde de uma unidade psiquiátrica, localizada em hospital geral público. Os participantes responderam a um instrumento com questões fechadas e abertas. Os resultados evidenciaram sensibilidade, empatia e motivação dos profissionais para contribuir na efetivação do projeto. Para isso, eles pontuaram a necessidade de mudanças na estrutura física, na gestão da unidade e na capacitação da equipe. Os participantes consideram que a implementação poderá auxiliar na recuperação da mãe e evitar o comprometimento no vínculo dela com o bebê, contudo sugerem a sistematização na modalidade intermitente. Assim, os resultados/sugestões da equipe constituem subsídios para as próximas etapas de implantação do alojamento.
Vivências de Automutilação sob a Lente da Gestalt-Terapia
Authors: Coelho Ana Lorena , Ming-Wau Carlos , Melo Anna Karynne , Leite Darla Moreira Carneiro
Published: September 2022

A automutilação é um ajustamento criativo disfuncional, considerada pela gestalt-terapia como uma retroflexão. Trata-se de um comportamento autodestrutivo em busca de lidar com o sofrimento no campo organismo-ambiente. Objetivamos compreender, sob a lente da gestalt-terapia, vivências de automutilação de pacientes internados por tentativa de suicídio. Utilizamos o método fenomenológico, nestas etapas: redução fenomenológica, descrição dos vetores internos ao fenômeno e explicitação da experiência em seus diferentes sentidos. Participaram do estudo quatro mulheres hospitalizadas por tentativas de suicídio e que praticavam automutilação. Realizamos atendimentos psicológicos às participantes, em seus leitos, cujos trechos sobre a automutilação foram registrados num diário de bordo e, em seguida, analisados. Constatamos que a automutilação foi uma forma de punição ao flagelar seus corpos com os cortes em busca de irem aos poucos se matando. Portanto, como um processo retroflexivo, a automutilação é um modo de autocontrole, evitação de contato e frustração a fim de um ajustamento criativo.
A (Não) Adesão ao Tratamento de HIV/Aids: Sentidos, Manejos Clínicos e Dilemas Bioéticos
Authors: Duarte Fábia Maria Ribeiro , Oliveira Cristiane , Silva Rosana dos Santos
Published: September 2022

O estudo analisa sentidos, manejos clínicos e dilemas bioéticos dos profissionais de saúde sobre a (não) adesão ao tratamento de pessoas com HIV/aids. Trata-se de uma pesquisa exploratória, de caráter qualitativo, com entrevistas semiestruturadas, dirigidas a profissionais de uma unidade de infectologia de um hospital público e submetidas à análise de conteúdo de Bardin. Os achados revelam que há uma diversidade de sentidos atribuídos à (não) adesão, com predominância da perspectiva individualista e racionalista para explicação do fenômeno. Diante dos casos de (não) adesão, os profissionais questionaram a autonomia do paciente, abordando os dilemas bioéticos em torno do sigilo e da confidencialidade do diagnóstico de HIV/aids. Os achados apontaram a necessidade de se pensar estratégias de cuidado guiadas pela elaboração de projetos terapêuticos singulares, bem como de se construir espaços de educação permanente em saúde para a reorientação das práticas de cuidado.
Factors in infertility score on referral and non-referral cases who underwent In Vitro Fertilization (IVF) treatment at a fertility clinic in Surabaya, Indonesia
Authors: Brahmana Nadhif Rashesa , Sa’adi Ashon , Yudiwati Rina
Published: September 2022

HIGHLIGHTS
1. Infertility score should be identified to obtain successful outcome of In Vitro Fertilization (IVF).2. Factors considered in determining the infertility score were examined.3. Each factor in infertility score (e.g, age, duration of infertility, menstrual cycle, pelvic pain etc.) has its own different degrees of severity that influence the outcome of IVF.
 
ABSTRACT
Objectives: To examine the factors used in infertility score on referral and non-referral cases who underwent IVF treatment at Fertility Clinic of Graha Amerta, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2014-2016
Materials and Methods: This research was a descriptive analytic retrospective study using secondary data from medical records at Fertility Clinic of Graha Amerta in 2014-2016. With a total sampling technique, a total of 342 referral and non-referral infertility cases were obtained. The variables in this study were the factors considered in infertility score.
Results: From a total of 342 cases, 44% had the wife's age in the range of 30-35 years, 80.1% had an infertile duration of > 3 years, and 54.7% had one type of pelvic pain, 68.4% still had regular menstrual cycles, and about 76% did not have a history of pelvic infection. On sperm analysis factor, there were 27.5% of men who fell into the severe category according to infertility score. There was a significant difference in the duration of infertility and sperm morphology in referral and non-referral cases.
Conclusion: Infertility score can be useful because each case has its own infertility factors with different degrees of severity, which leads to infertility.
Funcionamiento familiar y afrontamiento resiliente en padres de familia peruanos: estudio realizado durante la pandemia COVID-19
Authors: Callupe Laura Elizabeth , Mamani-Benito Oscar , Carranza Esteban Renzo Felipe
Published: September 2022

Con el objetivo de determinar si el funcionamiento familiar predice el nivel de afrontamiento resiliente en padres de familia que enfrentan el impacto de la pandemia COVID-19, se realizó un estudio predictivo y transversal sobre una muestra de 183 padres de familia del departamento de La Libertad, quienes fueron seleccionados bajo un muestreo no probabilístico de tipo intencional. Para recolectar datos se usaron dos instrumentos: Escala de Evaluación de Cohesión y Adaptabilidad Familiar (CESF) y la Escala Breve de Afrontamiento Resiliente (BRC). Sobre la base de un análisis de regresión lineal, se observó un ajuste adecuado del modelo (Prueba F = 35.924, p < .001), donde, el funcionamiento familiar (β = .407, p < .05) fue una variable que predice significativamente la resiliencia (R2 ajustado = .161). Asimismo, los valores t de los coeficientes de regresión beta de la variable predictora fueron altamente significativos (p < .01). En conclusión, el nivel de funcionamiento familiar predice el grado de afrontamiento resiliente en los padres de familia del departamento de La Libertad, durante la pandemia COVID-19.
Aprendizaje basado en proyectos y el desarrollo epistemológico en Licenciatura
Authors: Bontempo e Silva Luiza
Published: September 2022

Esta investigación tiene el objetivo de comprender qué efectos tendrá un programa de licenciatura, basado en el ABP, sobre el desarrollo de la auto-autoría de los estudiantes. Para tanto, se realizó un estudio cualitativo de enfoque biográfico-narrativo. El instrumento de construcción de la información fue entrevista a profundidad individual de duración aproximada de una hora o más. Las nueve participantes, voluntarias, son estudiantes de una licenciatura que aplica el método ABP en toda la formación. La información fue analizada a partir de las categorías preexistentes en la investigación anterior sobre desarrollo de auto-autoría, utilizando el Atlas.ti, como herramienta. Como resultados, se encontró que la experiencia práctica durante la formación profesional va a tener diferentes efectos en los jóvenes dependiendo de la posición de auto-autoría en que se encuentran. También se concluye que, por sí solo, el método ABP no genera movimiento a posiciones más sofisticadas, pero puede apoyar el movimiento ya incipiente.
A simulação como ferramenta de avaliação
Authors: Figueiredo Elfie Tomaz , Peixoto Júnior Arnaldo Aires , Peixoto Raquel Autran Coelho
Published: September 2022

Objetivos: analisar o uso da simulação como ferramenta de avaliação do aluno na aquisição de competência profissional. Métodos: trata-se de revisão narrativa da literatura em que foram realizadas buscas nas bases de dados PubMed e na SciELO, no período de 2000 a 2019, utilizando-se os termos de busca: simulação, educação médica e avaliação educacional. Resultados: após seleção e análise dos estudos, observou-se que a avaliação em ambiente simulado visa aplicar o conhecimento e habilidades, e atitudes diante de situações que simulem a prática real. O Objective Structured Clinical Examination (OSCE) é um modelo de avaliação com uma série de estações, em tempo limitado, nas quais o discente deverá executar ações específicas que englobam competências na assistência aos pacientes, comunicação médico-paciente, realização do exame físico, interpretação de exames complementares, elaboração de terapêutica específica e profissionalismo. O maior mérito da estratégia é a estruturação de situações-problema e a padronização de critérios de avaliação, reduzindo assim a variabilidade de fatores que podem interferir no processo avaliativo, como por exemplo, a complexidade de atendimentos em cenário real. Conclusão: a simulação eleva a validade de conteúdo e a confiabilidade do exame, o que promove maior homogeneidade na avaliação do aluno, permitindo aquisição de competências para promover maior segurança no cuidado e na relação médico-paciente.
Clinical significance of aetiological heterogeneity in classical Hodgkin lymphoma
Authors: Hjalgrim Henrik , Rostgaard Klaus
Published: September 2022

In this review we present contemporary understanding of aetiological heterogeneity in Hodgkin lymphoma, discuss how this may influence tumour phenotype and whether it does or may impact treatment outcomes. Many new treatments are being tested in this era. We especially discuss T-cell therapy and immune checkpoint blockade, because these two modern treatments are expected to have differential efficacy by the presence/absence of Epstein-Barr virus in the malignant Hodgkin-Reed-Sternberg cells. Survival after Hodgkin lymphoma is excellent in many patient strata with first-line treatment, but less so for patients with refractory or relapsing disease. On the other hand, this good prognosis also means that very large trials are needed to demonstrate superior efficacy of new treatment regimes. And our understanding of aetiological heterogeneity in Hodgkin lymphoma and how it affects prognosis is hampered for the same reason. We discuss the potential for fine-tuning risk stratification and treatment based on information that is little used today.
Transcriptomics insights into interpreting AMD-GWAS discoveries for biological and clinical applications
Authors: Ratnapriya Rinki
Published: September 2022

Genome-wide association studies (GWAS) have been successful in identifying genetic risk factors for a large number of complex diseases, including age-related macular degeneration (AMD), which is a highly heritable complex disease affecting millions of elderly individuals. However, the progress of elucidating the functional relevance of genetic findings in AMD has been slow, as most risk factors are non-coding, and we have little insight into the causal genes and disease mechanisms. In the last few years, gene expression regulation is emerging as a dominant mechanism through which GWAS risk variants lead to the disease. The purpose of this review is to provide an overview of how transcriptome studies can help in identifying the genes, pathways and therapeutic targets underlying GWAS discoveries in AMD. These approaches help pave the road for mechanistic understanding of GWAS findings and drive translational advances that will lead to improved AMD management and treatment.
NUT midline carcinoma presenting initially as thyroid cancer: a case report and review of treatment
Authors: Neumann Melissa , Hines Adam , Chang Qing , Seetharamu Nagashree , Lopez Carlos A.
Published: September 2022

The purpose of this abstract is to provide data on a 27-year-old woman with a rare and rapidly progressive cancer, Nuclear in Testis (NUT) carcinoma (NC), and to highlight possible treatment options for her specific gene translocation of NSD3-NUT. To our knowledge, this is the first case in the literature that was presented initially as anaplastic thyroid cancer. We propose that targeted therapy with a histone lysine methyltransferase inhibitor may be of benefit as adjunctive therapy in patients with the NSD3-NUT gene translocation.
Wine labelling with the list of ingredients: context, consumer’s perception and future challenges
Authors: La Guerche Stéphane , Tomasoni Mario , Sanchez-Recarte Ignacio , Teissedre Pierre-Louis , Cotarella Riccardo , Svinartchuk Tatiana , Ruf Jean-Claude
Published: September 2022

Since 2011, Regulation (EU) No 1169/2011 on the provision of food information to consumers (FIC) exempted alcoholic beverages above 1.2% abv from the mandatory list of ingredients and the nutrition declaration. In 2017, the European Commission invited the alcohol beverages industry to respond to consumers’ expectations and to present, within a year, a proposal of self-regulation on ingredients and nutritional information covering the whole sector.
Effects of Cathinones (Bath Salts) On Cultured Primary Neurons/Astroglia Cells and Neurobehavioral Functions in Mice
Authors: Selig Tyler M. , Pierre Kevin , Arja Rawad Daniel , Dagra Abeer , Gold Mark , Raghavan Vijaya , Kobeissy Firas , Yang Zhihui , Wang Kevin K. W.
Published: September 2022

This study aims to examine the cytotoxicity mechanisms of synthetic cathinone (bath salts) on rat primary cultured neurons and primary astroglial cells, and to assess their neurobehavioral effects on mice. We administered methylenedioxypyrovalerone (MDPV) to both rat primary cultured neurons and primary astroglial cells to assess cell injury. We also analyzed the effects of MDPV on these cell cultures using immunocytochemistry. We utilized western blotting to assess the breakdown of αII-spectrin and glial fibrillary acidic protein (GFAP) induced by MDPV. The western blotting experiment also included calpain and caspase inhibitors (SNJ1945 and Z-D-DCB, respectively) and pro-apoptotic and pro-necrotic agents (Staurosporine and calcium ionophore A23187, respectively). Lastly, we assessed MDPV’s effects on behavioral effects using rotarod, locomotor activity, elevated plus maze, Morris water maze, forced swimming, and open field tests. MDPV caused a dose-dependent release of LDH in both cerebrocortical neuron-astroglia mixed cultures and primary astroglial cultures. MDPV also caused neurite breakages and astroglial process retraction on immunocytochemistry. Lastly, MDPV induced αII-spectrin breakdown in western blotting experiments. Co-administration of calpain and caspase inhibitors reduced the degradation of αII-spectrin and GFAP. MDPV administration also increased anxiety-like behavior and locomotor activity in the mice. Synthetic cathinones, which share structural similarities with methamphetamine, also induce significant neurotoxic effects and neurobehavioral effects on rodent models. These neurotoxic effects are likely mediated by calpain and caspase-induced apoptosis and necrosis, while astroglial death is likely only due to calpain activation. Therefore, further research may focus on pharmacological interventions targeting these pathways to mitigate the cytotoxic impact of cathinones in humans.
Accelerating Extreme Search of Multidimensional Functions Based on Natural Gradient Descent with Dirichlet Distributions
Authors: Abdulkadirov Ruslan , Lyakhov Pavel , Nagornov Nikolay
Published: September 2022

In this work, we explore the extreme searching of multidimensional functions by natural gradient descent based on Dirichlet and generalized Dirichlet distributions. The natural gradient is based on describing multidimensional surface with probability distributions, which allows us to reduce changing the accuracy of gradient and step-size. In this article, we propose an algorithm of natural gradient descent based on Dirichlet and generalized Dirichlet distributions. We demonstrate that the natural gradient descent with step-size adaptation with Dirichlet and generalized Dirichlet distributions has higher accuracy and does not take a large number of iterations for minimizing test functions than gradient descent and Adam.
Efficient RO-PUF for Generation of Identifiers and Keys in Resource-Constrained Embedded Systems
Authors: Martínez-Rodríguez Macarena C. , Rojas-Muñoz Luis F. , Camacho-Ruiz Eros , Sánchez-Solano Santiago , Brox Piedad
Published: September 2022

Generation of unique identifiers extracted from the physical characteristics of the underlying hardware ensures the protection of electronic devices against counterfeiting and provides security to the data they store and process. This work describes the design of an efficient Physical Unclonable Function (PUF) based on the differences in the frequency of Ring Oscillators (ROs) with identical layout due to variations in technological processes involved in the manufacture of the integrated circuit. The logic resources available in the Xilinx Series-7 programmable devices are exploited in the design to make it more compact and achieve an optimal bit-per-area rate. On the other hand, the design parameters can also be adjusted to provide a high bit-per-time rate for a particular target device. The PUF has been encapsulated as a configurable Intellectual Property (IP) module, providing it with an AXI4-Lite interface to ease its incorporation into embedded systems in combination with soft- or hard-core implementations of general-purpose processors. The capability of the proposed RO-PUF to generate implementation-dependent identifiers has been extensively tested, using a series of metrics to evaluate its reliability and robustness for different configuration options. Finally, in order to demonstrate its utility to improve system security, the identifiers provided by RO-PUFs implemented on different devices have been used in a Helper Data Algorithm (HDA) to obfuscate and retrieve a secret key.
Tissue Engineering in Gynecology
Authors: Brownell David , Chabaud Stéphane , Bolduc Stéphane
Published: September 2022

Female gynecological organ dysfunction can cause infertility and psychological distress, decreasing quality of life of affected women. Incidence is constantly increasing due to growing rates of cancer and delaying of childbearing age in the developed world. Current treatments are often unable to restore organ function, and occasionally are the cause for female infertility. Alternative treatment options are currently being developed in order to face the inadequacy of current practices. In this review, pathologies and current treatments of gynecological organs (ovaries, uterus, and vagina) will be described. The state-of-the-art of tissue engineering alternatives to common practices are evaluated with a focus on in vivo models. Tissue engineering is an ever-expanding field, integrating various domains of modern science to create sophisticated tissue substitutes in the hopes of repairing or replacing dysfunctional organs using autologous cells. Application to gynecology has the potential of restoring female fertility and sexual wellbeing.
Academic production in the initial formation of physical education teachers: is there room for the internship?
Authors: Medeiros Filho Antonio Evanildo Cardoso de , Silva Lucas Souza , Magalhães Junior Antonio Germano
Published: September 2022

The study aimed to identify the theoretical-methodological choices in the monographs presented in the Physical Education course of a public university between the years 2008 and 2019, in order to quantify and characterize the works that have the Supervised Curricular Internship as an investigative object. This is a documental research, and it was collected information from 355 productions. The results indicate the predominant use of the qualitative approach (n = 167; 47.0%), followed by the quantitative (n = 161; 45.3%), and mixed (n = 27; 7.7%), besides the questionnaire, documents and interviews as the most requested data collection techniques. Although it is a degree course, the number of works in the areas of activity inherent to the bachelor's degree is predominant (n = 207; 58.1%). We evidenced 5 (1.4%) works that problematize the Internship in teacher training. The reality investigated requires dialogues, reflections and investigations about the academic production related to teacher education and the Supervised Curricular Internship.