bluuebunny/crossref_metadata_2025 huggingface dataset:
Using Library activities to develop teaching-learning French at Faculty of Education at the Francophone Center, National University of Lao
Authors:   National University of Laos, THAMMASALO Olady
Published: September 2024

This research report combines two objectives 1). to study additional activities outside the classroom to improve the learning of French in the first year of the French license at the Department of Foreign Languages, Faculty of Education National University of Lao, and 2). to study the satisfaction of the students with the activities. In addition, these activities are intended to allow students to usefully occupy their free time and to promote the practice of language skills and group work. The target group of the research is students from 1st to 3rd year, with a total of 40 people, 28 women. They have an intermediate level of French and they all need to participate in the activity. The research tool was a questionnaire based on the 5-level Likert rating scale. The statistics used to describe the search results are frequency, percentage, and average. The activities in which most students participate with interest are “talking with French people” and “searching for documents,” so the research group can say that both activities are very interesting (F = 97.5% and F = 100%). The research group can therefore say that both activities are very interesting (F = 97.5% and F = 100%). In addition, the research group found that the level of satisfaction is very high in terms of reading French books (58%), in terms of watching films French 67%, in terms of conversation with French speakers (52.5%), in terms of listening to French music 50%, in terms of computer learning (50%) and in terms of finding passages (50%). Furthermore, students develop and strengthen their knowledge of France. Students can also practice communication and have the courage to express themselves in French. Therefore, teachers must also teach French culture because it is very necessary that students know well. Thus, the research group can conclude that these activities outside the classroom contribute to stimulating students' desire to learn French. The various activities were achievement for the goal setting due to the activities management was increased students’ interest in learning French while teachers’ teaching.
The Development of Using Lao Language for Communication of Teacher in Phonethong District, Luangprabang Province Academic year 2020 - 2021
Authors:   Souphanouvong University, CHANHTHAHONG Khamxay
Published: September 2024

The purposes of research are: 1) to develop the teaching of Lao language for communication for teachers at Phonthong secondary School, Phonethong District, Luang Prabang Province, 2). to examine the results of theteaching of Lao language for communication for teachers, and 3). to investigate the teachers’ satisfaction with the learning activities in teaching Lao language for communication for teachers at Phonthong secondary School, Phonethong District, Luang Prabang Province. This study model was the measurement of before and after the pilot activities which employed the one – Group Pretest – Posttest Design for data collection. The target group consisted of 23 Lao language teachers at Phonthong Secondary School, Phonthong District, Luangprabang Province for the academic year 2021. The instruments used for the study comprised of 1) lesson plans on the subject of Lao language for communication for teachers. 2) pre – post tests of training achievement, 3) a questionnaire for eliciting the teachers’ opinions concerning their satisfaction towards the learning activities on the Lao language teaching for communication for teachers, and 4) the assessment form of ability to speak the Lao language for trainees and the collected data was analyzed by means of calculating arithmetic mean, standard deviation and percentage. The result vealed that: 1. The learning activities using teaching the Lao language for communication for teachers as was statistically significant at 0.00 difference with the, mean (after learning) of 12.83 and S.D. of 2.33 (12.83, SD=2.33) which is higher than the mean ( before learning ) of 15.91 and S.D. of 1.96 (15.91, SD=1.96) which is in accordance with the established assumptions. 2. The participants showed the “highest” level of satisfaction towards the learning activities using the teaching of the Lao language for communication for (4.51, SD=0.61). However, when considering each aspect, it could be seen that the participants show the highest “highest” level of satisfaction towards the measurement and evaluation (4.56, SD= 0.60), followed by the environment aspect (4.55, SD= 0.53), teaching and learning activities, application, lesson content and teaching methods (4.50, SD= 0.54), (4.49, SD= 0.61), (4.46, SD= 0.61), (4.43, SD= 0.56) respectively, and they were also concistant with the established assumptions.
Cell Experiment Equipment by Using Ashes as Electrolytes
Authors:   Souphanouvong University, VONGVILAY Chanpheng
Published: September 2024

This article presents information about an experiment on how to create simple galvanic cell experiment equipment by using waste ash from burning as electrolytes, a copper plate as a cathode, and a zinc plate as an anode. The main purpose is to create a set of experimental equipment for teaching physics under the title of electrochemistry, to examine the possibility of generating electricity from ash, to study the change of the mixture ratio between the ashes and water that affects the open circuit voltage (OCV), to compare the value of the open circuit voltage from the sedimentation ashes electrolyte and non-sedimentation ashes electrolyte, and to study the pH value of the ash’s electrolyte within two hours. The research revealed that it can create five sets of galvanic cells by using different quantities of ashes, and it was found that the ashes from burning can generate electricity. The same type of ash with a different quantity will give almost the same OCV values, and changing the mixture ratio between ash and water will not affect the OCV values, which found that the mixing ratio between water and dry ash to become an electrolyte must use a minimum mixing ratio of water equal to ash or use a ratio of water more than ash to mix together. The results of measuring the value of OCV over a period of 2 hours found that the average value is almost constant, equal to 0.7 V. Here, we found that if the ash is allowed to settle, the value of OCV will decrease slightly, and if the ash is not allowed to settle, the value of OCV is constantly unchanged. It was also found that the pH value of the ash in each galvanic cell during the period of 2 hours was the same, with an average high alkalinity of about 13. This shows that alkaline electrolytes can generate electricity and have almost constant electricity. These five devices can be applied as a teaching tool for the Physics and Chemistry subject in the title of electrochemistry for students at the secondary school level and bachelor’s students because of an easy way to fabricate galvanic cells. The materials used are cheap and easy to find. It can also be used to study the characteristics of electrical conductivity in ash’s electrolyte and the characteristics of ash’s electrolyte.
Factors Influencing on Students’ Learning Problem at Primary School in Phonthong District, Luang Prabang Province
Authors:   Souphanouvong University, Silivanh Sommay , Vongvilay Chanpheng
Published: September 2024

This research focuses on factors as problems influencing student learning quality at primary school in Phonthong District, Luang Prabang province. The objective included 1) the level of importance of the problems to the student’s learning quality at primary school in Phonthong District, Luang Prabang province, and 2) factors as problems influencing student learning quality at primary school in Phonthong District, Luang Prabang province. The study was conducted with 25 primarry school and 535 primary students from grade 3 to grade 5. This quantitative research utilized questionnaires for data collection and the data were analyzed using the descriptive statistic by Program SPSS and inferential statistics by Program MATLAB. The results that the condition of learning problems of primary school students in Grade 3 - Grade 5 in Phonthong District, Luang Prabang Province as a whole is a moderate level of problems such as student's personal, academic behavior, parents' attention to the student's education, the location of the school, the relationship between students and friends in the classroom, the relationship between the student and the teacher and the teacher's behavior towards the student as a whole are moderate level. So, the most problematic factors for primary school students are the parents' attention to the students' learning, the teacher's behavior towards the students, the student's learning habits, the school's location factor, the relationship between the students and the teacher, the relationship between the students and their friends in the class and finally the personality factors of the students respectively.
Diagnostic on logistic system in two provinces (Case study: Savannakhet and Champasack)
Authors:   Champasack University, SACKBOUAVONG Khoune
Published: September 2024

The study entitled "Analyzing the logistics system of agricultural products ". A case study: Savannakhet and Champasak Provinces. The data used in the study includes both secondary data and primary data obtained from the sample group. The research team conducted a detailed interview with 100 entrepreneurs who are actually involved in agricultural business. The results of the study found that: most of the farmers use six-wheeled vehicles/wheels to transport produce/goods, which numbered 58 units as a percentage, equal to 58% because the farmers used wheeled vehicles which can carry medium to large quantities and are suitable vehicles for carrying goods easily. In terms of the use of cattle-type cargo vehicles, most of them use six-wheeled vehicles/wheels covering 50% and ten-wheeled vehicles covering 50%, chicken transporters covering 78.57% and rice-type transporters covering 72.73%. Regarding the distribution channel of the produce/goods of the farmers, it was found that most of them chose the channel from the farm/garden-local market in the province-wholesaler or chose the channel from the farm/garden-factory-wholesaler-market and the channel from the farm/garden-distribution point accounted for 17%. The results of the test of the factors that affect the management of the logistics management of agricultural products found that the management of the logistics management of small products affects the business up to 76%, which means that the business can have a good opportunity to grow.
Impact of foreign direct investment on the economic growth of Lao PDR
Authors:   Souphanouvong University, XIONGTOUA Tongvang
Published: September 2024

This paper aims to study impact of foreign direct investment on the economic growth of Lao PDR, with the variable of foreign direct investment in the agricultural sector (FIA), the industrial sector (FII) and the service sector (FIS) and the dependent variable that is the economic growth of Lao PDR (GDP), as a time series from 1991-2020, focusing on the analysis using the multiple regression model with the ordinary least squares method, the effect of investment on economic growth in the short-run by the method of Granger causality and the effect of investment on long-run economic growth with Johansen's cointegration method: The results of the analysis in the regression model show that the foreign direct investment in the agricultural sector is accepted null hypothesis that means, it has no effect on the economic growth of Lao PDR, the foreign direct investment in the industrial sector (FII) and the service sector (FIS) the test results reject null hypothesis with significance of 0.05, indicating that the investment results in both sectors have an effect on the economic growth of Lao PDR. The results of the analysis of foreign direct investment to the economic growth in the short-run shows that the coefficient of the foreign direct investment in service sector has a positive value and rejected null hypothesis (H0) with significance of 0.05 indicating that there is a short-run effect on the economic growth. For foreign direct investment in the agricultural and industrial sectors, there is no effect on the short-run economic growth of the Lao PDR because the null hypothesis (H0) is accepted. The results of foreign direct investment to the economic growth in the long-run shows that the coefficient of foreign direct investment in the agricultural sector has a negative value, indicating that there is no effect on the economic growth in the long-run, for the coefficient of foreign direct investment in the industrial and service sectors were a positive value and rejected null hypothesis (H0) with significance of 0.05, when there is an increase in investment in those two sectors, it will result in a long-run effect on the economy (GDP) to grow.
A LUDICIDADE PARA A INCLUSÃO DE ESTUDANTES COM NECESSIDADES EDUCACIONAIS ESPECÍFICAS NO ENSINO MÉDIO
Authors: Molina Gustavo , Souza Sawana Araújo Lopes De
Published: September 2024

Playful tools, which have already been shown to help the learning process in the early stages of basic education, have not been explored as much in the high school. To fill this knowledge gap, the aim of this research is to reflect on the benefits of playfulness for inclusion in high school. This is a narrative bibliographical study with a qualitative approach. Dissertations and thesis were selected from the CAPES, SciELO and ANPED databases. The results indicate that with playful resources and practices, a dialogic learning environment can be built, favoring the expression of emotions and interests. It is considered that playful practices are tools for building trust between teacher and student, as well as arousing curiosity and motivating learning processes. Through games it is possible to encourage adaptation to social rules, stimulate interaction between peers and improve behavioral and emotional aspects that favor cognitive development.
EDUCAÇÃO INFANTIL: ALICERCE PARA O FUTURO
Authors: da Silva Danyelli Baptista , de Souza Elza Ribeiro , Schon Gislaine , de Souza Lidiane da Silva Rocha , dos Santos Luiza Savelli , da Silva Maria Cecília Generoso , Valadares Raquel Rocha Drews , Silva Raquel Santos , da Silva e Silva Sílvia Cristina , de Oliveira Sueli Aparecida Correia
Published: September 2024

O artigo discute a importância da educação infantil como etapa fundamental para o desenvolvimento integral das crianças e como alicerce para o sucesso escolar e a formação cidadã. A educação infantil, além de promover o desenvolvimento cognitivo, motor, emocional e social, prepara as crianças para os desafios futuros ao proporcionar um ambiente rico em estímulos e aprendizado. O texto também aborda a relevância dessa fase na promoção da equidade social, destacando que o acesso universal e de qualidade à educação infantil pode reduzir desigualdades e ampliar oportunidades. Contudo, o artigo alerta para desafios como a falta de infraestrutura, materiais pedagógicos adequados e a necessidade de formação específica para os profissionais. Conclui-se que investir na educação infantil é garantir um futuro mais justo e promissor para as crianças e para a sociedade como um todo.
AS DIFICULDADES DE APRENDIZAGEM NA ALFABETIZAÇÃO: 5° ANO DO ENSINO FUNDAMENTAL DE UMA ESCOLA MUNICIPAL DE BARRA DO GARÇAS – MT
Authors: Cruz Mônica Rosa da , Filsner Kenia Maria da Silva , Azanki Renia Maria da Silva , Franco Aldenice de Sousa , Silva Odirlene Maria da , Silva Maria de Fátima da , Abud Nilma Mariana de Oliveira , Vitorino Ana Flávia Castilho de Souza
Published: September 2024

Este trabalho tem o objetivo de apresentar os resultados de uma Pesquisa-ação realizada numa Escola Municipal da cidade de Barra do Garças – MT. Trata-se de pesquisa exploratória desenvolvida pela metodologia qualitativa, a intervenção pedagógica foi executada durante a regência de aulas no Estágio Supervisionado III do curdo de Pedagogia Licenciatura, com carga horária de 20 horas – no período de março a junho do ano de 2018; tendo como público alvo uma turma de turma do 5º ano do Ensino Fundamental, da qual foi selecionado um aluno para objeto da pesquisa. Este estudo se justifica pela necessidade de formação docente sob o crivo da pesquisa científica e pelos desafios inerentes ao processo de escolarização e alfabetização.
MPOX: DESAFIOS ATUAIS NA PREVENÇÃO, DIAGNÓSTICO E TRATAMENTO NO CONTEXTO DA EMERGÊNCIA DE SAÚDE PÚBLICA
Authors: Cardoso Victoria Karoline Libório , Pinho Denis Alves , Santos Fhelipe da Silva , Silveira Gabriel Barroso Novo da , Braga Gustavo Pires , Silveira Santos Letícia Gabrielly da , Almeida Marines de Sousa , Grequi Paula Rodrigues , Oliveira Raíssa Freitas de , Cattaneo Sara Gabriella de Azevedo
Published: September 2024

A MPOX, do gênero Orthopoxvirus e família Poxviridae,  foi identificada pela primeira vez em 1958 em macacos de laboratório, e o primeiro caso humano foi registrado em 1970, na República Democrática do Congo. Desde então, a doença manteve-se endêmica em algumas regiões da África, mas recentes surtos internacionais destacaram seu potencial pandêmico, elevando a MPOX ao status de emergência global de saúde pública. A análise dos desafios enfrentados ao longo de todo o espectro da resposta à MPOX revela limitações significativas nas estratégias preventivas, dificuldades no diagnóstico precoce e barreiras ao acesso a tratamentos adequados. O âmbito da prevenção é marcado pela falta de vacinas amplamente disponíveis e pela necessidade de estratégias de vacinação mais eficazes, com ênfase em grupos de risco e regiões com infraestrutura de saúde insuficiente. No campo do diagnóstico, observa-se uma carência de métodos específicos e acessíveis que possam ser amplamente implementados, especialmente em áreas remotas ou com recursos limitados. A complexidade dos sintomas da MPOX, que podem se assemelhar a outras doenças, dificulta a detecção precoce e o manejo correto dos casos. No tratamento, as opções terapêuticas são restritas, com antivirais específicos ainda em desenvolvimento e a necessidade de suporte clínico adequado, frequentemente inacessível em muitas regiões afetadas. A discussão também aborda o papel essencial da pesquisa e inovação, destacando o desenvolvimento contínuo de antivirais, novas vacinas e a adaptação de tecnologias de diagnóstico que possam ser aplicadas de maneira prática e eficaz em diferentes contextos. Além disso, reforça-se a importância de políticas de saúde pública integradas e da cooperação internacional como pilares para fortalecer a resposta à MPOX e aprimorar a capacidade global de enfrentar futuras emergências sanitárias. Uma abordagem multidisciplinar, envolvendo colaboração entre cientistas, profissionais de saúde, governos e organizações internacionais, é fundamental para mitigar os impactos da MPOX e assegurar uma resposta ágil e coordenada a crises de saúde emergentes.
COMO O TIKTOK MOLDOU AS PERCEPÇÕES DE MARCA E CRIOU ENGAJAMENTO NOS ÚLTIMOS ANOS
Authors: Vitalino Juliana , Werner Luisa , Linhares Maria Clara
Published: September 2024

O TikTok, com mais de 1 bilhão de usuários ativos, se consolidou como uma plataforma de grande relevância para o marketing digital, especialmente entre os públicos Millennials e da Geração Z. Sua popularidade não só revolucionou a forma de consumir conteúdo, como também transformou as estratégias de marketing ao exigir abordagens mais autênticas, criativas e instantâneas. Marcas que se adaptaram ao TikTok, como a Cimed e o Duolingo, conseguiram usar a plataforma para aumentar sua visibilidade e fortalecer o engajamento com o público. O estudo analisou as estratégias inovadoras que essas empresas adotaram para aumentar a visibilidade e engajamento, como o uso de influenciadores, desafios virais e a integração de funções de comércio social, que permitiram uma maior aproximação com seus consumidores e a otimização de resultados em campanhas publicitárias.
AUTOMAÇÃO E PROCESSOS ADMINISTRATIVOS: DESAFIOS E OPORTUNIDADES NA ERA DIGITAL
Authors: Barreto Danilo Alves Paes , Gomes Demétrius Albuquerque , Xavier Matheus Henrique Rabelo , Vasconcelos José Antônio Carvalho
Published: September 2024

A era digital tem impulsionado transformações significativas nos processos administrativos, destacando a automação como um fator chave na busca por eficiência e competitividade. Este artigo explora os desafios e as oportunidades que a automação traz para a gestão administrativa, analisando como as tecnologias emergentes estão remodelando o cenário organizacional. A automação de processos administrativos permite a redução de erros humanos, maior agilidade nas operações e otimização de recursos, o que pode levar a uma significativa redução de custos operacionais. Contudo, essa transição não é isenta de desafios. A integração de novas tecnologias exige um alto investimento inicial, treinamento especializado e a superação de resistências culturais dentro das organizações. Além disso, a automação pode gerar preocupações sobre a substituição de empregos e a necessidade de redefinir o papel dos trabalhadores. O artigo discute ainda como as organizações podem mitigar esses desafios, adotando uma abordagem estratégica que combine inovação tecnológica com gestão de mudança eficaz. Conclui-se que, embora a automação apresenta desafios significativos, as oportunidades proporcionadas pela digitalização dos processos administrativos são amplas, podendo resultar em organizações mais ágeis, inovadoras e competitivas.
Effects of Climate Change on Bee Health
Authors: Gurcay Metin
Published: September 2024

Climate change is a problem that aff ects many sectors around the world and seriously threatens human life. Th is change has profound impacts on agriculture, water resources, wildlife, and ecosystems. For an important species such as bees, the consequences of these changes are expected to be serious. Bees are a critical part of natural cycles and agricultural production, and bee products have signifi cant nutritional, health, and economic value. Th e impacts of climate change on bees are expected to naturally aff ect bee products. In this chapter, we will examine the possible impacts of climate change on the chemical and biological properties of bee products.
Effects of Climate Change on Chemical and Biological Properties of Bee Products
Authors: Izol Ebubekir
Published: September 2024

Global warming and the resulting global climate change bring various biotic and abiotic stress factors such as sharp seasonal change, unexpected climate events, extreme temperatures, and the greenhouse gas eff ect. People worldwide are directly and indirectly aff ected by global climate change. Among all cross-pollinators, honey bees, with approximately 80% rate, are the organisms most adversely aff ected by global climate change. Th e decline of bees leads to a decrease in fl ora and biodiversity, plants being forced to self-pollinate, and consequently the sensitive plants to biotic and abiotic stress conditions grows, a decrease in agricultural yield, and disruptions in the food supply chain. In impoverished and remote areas where medical drugs cannot be delivered, people who practice alternative medicine (Apitherapy) using bee products also find it increasingly difficult, or impossible to cope with diseases. Global warming and global climate change require governments to act collectively, without delay, to develop and implement policies.
Construing the doctoral examiner: what the doctoral student should know
Authors: Jankovicz Devi
Published: September 2024

Doctoral candidates often worry about how their constructivist epistemology will be received, especially if their examiners come from a positivist background. The issue affects candidates in the more conventional psychology departments, and in the business and management schools too. Methodology textbooks used by students, supervisors and examiners don’t offer a unified terminology or a consistent analytic framework for the epistemological issues involved. An exercise in student-examiner sociality, this paper seeks to remove some possible confusions arising from an imprecise use of the terms ‘method’ and ‘technique’, and from the simplistic use of such constructs as constructivist-positivist, subjective-objective, and qualitative-quantitative.
A PCP approach to conflict resolution in Learning Communities
Authors: Davidson Ann-Louise , Naffi Nadia , Raby Carole
Published: September 2024

Over the past three years, we have been developing learning communities (LCs) with teachers and other school personnel. The objective of these LCs is to improve school success and student perseverance. We took a grassroots perspective to develop a pedagogical leaders LC with the purpose of generating specific LCs between schools. This involved determining priorities, identifying strengths, interests and ambitions collectively. The process generated a significant amount of tensions, especially when participants had opposite visions and perspectives. This paper describes the emergence of conflict and discusses how we used Personal Construct Psychology (PCP) to allow the constructs that underlie these tensions to emerge and turn them into engines of development for LCs.
What does taking care of you say about me? How professionals in Nursing Home look at elderly people
Authors: Buongiomo Viviana , Pagliardini Cecilia
Published: September 2024

The present research is grounded in the authors’ experience of working with elderly people and their awareness of a cultural background that conceives the elderly in a rather preemptive and constellatory way. We used Personal Construct Psychology (PCP) as a lens to explore constructs and experiences around the caring relationship and assistance of elderly people, within a Nursing Home unit comprising social workers and nurses. From the thematic analysis of 17 semi-structured interviews emerged some commonalities in terms of preemptive and regnant constructions of their work and stereotypical constructions of the elderly person. Some minor difference emerged in terms of propositional constructions. The present study highlights the importance of facilitating supporting and developmental opportunities for care-providers.
Tales of Storytelling: an interview with Giovanna Conforto
Authors: Scaglione Daniela
Published: September 2024

Giovanna Conforto is a world-known storyteller. She has taught, performed and consulted in Italy and abroad. Her collaborations include Uffizi Galleries in Florence, Chulalongkorn University in Bangkok and the Global Science Opera. Currently, she teaches at the International School of Storytelling (Emerson College – UK) and at the Master on Arts Management of IED University in Rome.
Evaluation of the use of Antihypertensive Drugs in Outpatient Hypertension Patients at the Lasinrang Regional General Hospital, Pinrang Regency in 2023
Authors: Yuliana Dewi , Agus Asfira , Azizah Rizqi
Published: September 2024

Hypertension is a complex condition in which blood pressure is permanently above normal. Hypertension is an increase in systolic blood pressure of more than equal to 140 mmHg and diastolic more than equal to 90 mmHg. This study aims to identify how antihypertensive drugs are used in hypertensive patients at the Lasinrang Regional General Hospital, Pinrang Regency. This study is a non-experimental research with a descriptive design taken retrospectively. The sample in this study is all outpatients with a diagnosis of hypertension at the Lasinrang Regional General Hospital in 2023. The sampling technique used is purposive sampling. The sample of this study is medical record data on hypertension patients in 2023 which is adjusted to the inclusion criteria. The results of the study showed that from 83 samples consisting of 50 women and 33 men, all of which met the inclusion and exclusion criteria, and showed a prevalence of age that dominated around 58-65 years (49,40%). In the evaluation of drug use, outpatient hypertension patients at the Lasinrang Regional General Hospital, Pinrang Regency had an indication accuracy of 100%, 100% drug accuracy, and 100% dose accuracy.
The potency of bioactive constituents in Piper betle L. for Alzheimer Targeting on Caspase-3: in silico studies
Authors: Putri Anindya Calista Nabila , Ashriany Raissa Rerey , Salsabila Sitti Kesya , Rahmaharva Naila Dwi , Muljono Fajar Oktavian , Fardhan Firghi Muhammad , Novitasari Dhania
Published: September 2024

Alzheimer’s disease (AD) is a neurodegenerative condition that can disrupt memory, cognition, and neurological functions, Recent studies highlight caspase-3 as a potential target, with several lines of evidence pointing to the enzyme's possible role in the onset of AD. Several findings revealed that betel leaf was also examined to treat AD by targeting acetylcholinesterase in vitro and in silico, yet no evaluation had not been done in caspase-3 activity. Using molecular docking, Lipinski's and PreADMET prediction, an in-silico analysis of compounds found in betel leaf (Piper betle L.) was conducted in order to determine whether these compounds could be applied as therapeutic candidates in the treatment of Alzheimer's. To ascertain the drug similarity and ADMET profile of the evaluated ligands, the Mcule and PreADMET sites were used in the studies, which were followed by the molecular docking simulation software AutoDock. The findings demonstrated that all the tested compounds passed the physicochemical features based on Lipinski rule. Further analysis then showed that arecoline bound to the critical amino acid that involved in caspase-3 inhibition. Further evaluation needs to be done to confirm the molecular mechanism of P. betle leaves to AD.
Preliminary Study on Different Calcination Temperature of TiO2/Eggshell Composite Using Sol-Gel Method
Authors: Jaafar Hidayani , Nik Jid Nik NorHidayah , Ameram Nadiah
Published: September 2024

The study investigated the impact of varying calcination temperatures on the band gap of a TiO2/eggshell (TE) composite. The composites were synthesized via the sol-gel method and subjected to different calcination temperatures (400°C, 450°C, and 500°C). Characterization techniques including Thermogravimetric Analysis (TGA), UV-Visible Spectroscopy (UV-Vis), and X-Ray Diffraction (XRD) were employed. Among the different calcination temperatures, the TE 450°C composite exhibited optimal absorbance, indicating a potential enhancement in photocatalytic performance. This suggests that the calcination at 450°C provided favourable conditions for the composite properties. Furthermore, the band gap measurements of the composites ranged from 3.25 eV to 3.48 eV. This range indicates the ability to maintain the inherent stability of TiO2 while ensuring sufficient light absorption, crucial for effective photocatalysis. Overall, the study highlights the significance of calcination temperature in tailoring the properties of TiO2-Eggshell composites, with the calcination temperature at 450°C composite demonstrating promising characteristics for photovoltaic applications and require more exploration.
Zn-Doped Calcium Copper Titanate Synthesis via Microwave-Assisted Technique
Authors: Sulaiman Muhammad Azwadi , Muhamad Sharifuddin Syifa’ , Anadin Norzafirah , Mohd Pabli Fathin Asila , Mohamed Julie Juliewatty , Ibrahim Norfadhilah , Ali Arlina , Masri Mohamad Najmi
Published: September 2024

Electroceramic material has become significant in the recent development of electronic parts such as capacitors, resonators, and sensors. The previous study on calcium copper titanate (CaCu3Ti4O12, CCTO) showed that CCTO exhibits a colossal dielectric constant, up to 105 for bulk materials using a conventional synthesis route (calcine and sinter at 900 - 1040? for 9 - 12 hours). The high firing temperature and longer reaction time were undesirable because they would increase production costs and be time-consuming. Alternately, research findings on doping with donor or acceptor elements were proven to be an effective technique for improving dielectric properties. Thus, the Zn-doping (Zn= 0, 1, and 3 mol%) method increased the dielectric constant in CCTO. The study successfully synthesized Zn-doped CCTO at 700? with a soaking time of 40 minutes using a microwave-assisted technique (calcined and sintered). Then, the samples were characterized using XRD and an impedance analyzer. The CCTO crystal formation was examined through an XRD pattern, and semi-quantitative analysis indicated that 1 mol% of Zn-doped recorded optimum formation reaction after calcining (56.5 wt%) and as-sinter (70.3 wt%). However, despite the low formation of CCTO crystal structure in 3 mol% of Zn-doped (34.9 wt%), it has the highest dielectric constant, and the dielectric loss was reduced at high frequency.
Innovative Composite Materials for Improving Structural Integrity and Longevity in Civil Engineering Applications
Authors: Alsultan Qusay Hatem , Abdulbaqi Azmi Shawkat , Nejrs Salwa Mohammed , Abd alla Israa Hussain , Jabur Younus khalaf , Jassim Salah Ayad , Mohammed Mohammed kareem , Sulaiman Bahjat Hardan , Shawqi Omar Salah Al deen , Mohameed Othman jasim , Abed Tareq Hamad , Panessai Ismail Yusuf , Khalaf Haitham Abbas
Published: September 2024

The following research is on substantial developments of composite materials to improve the structural integrity and durability of construction in civil engineering. Traditional materials—like steel and concrete—have a host of problems associated with them, such as being vulnerable to corrosion, requiring frequent maintenance, and having limited lifespan. This paper reviews such issues in relation to the application of composite materials that are known to have improved properties, such as high strength-to-weight ratios, improved corrosion resistance, and better durability. The challenge posed to civil engineering, however, remains to be the limited durability and high maintenance cost of traditional construction materials. Due to environmental and mechanical stresses, these materials degrade and have resulted in frequent repairs and replacements, eventually increasing lifecycle costs of infrastructure projects. Key objectives of this research include the investigation of the very latest developments in composite materials, the assessment of their impact on the structural integrity and longevity of civil engineering constructions, and the economic benefits of reduced maintenance and longer service life for structures due to these improved materials. These are some of the contributions of the study: it showed that composite materials have much better performance than traditional materials in load-carrying capacity, resistance, and life; comparative analyses establishing dramatic money saving by large order in maintenance cost and lifecycle cost using composites, as compared to traditional materials; and showing the versatility of composite materials for general civil engineering applications like bridges, tunnels, pipelines, and building structures. The results show that composite materials increase the life span of constructions and structures related to civil engineering by a tremendous amount: for example, the load-bearing capacity is improved by 20%, the life span of pavement and bridges increased by 200–400%, the maintenance frequency by 50%, and the maintenance cost by 60%, which justifies their economic benefits very clearly. It has improved thermal insulation, reduced weight for the structural components, and more resistance to degradation by environmental elements, which makes composites a better solution compared with conventional materials. Generally speaking, this paper tries to bring out the prospect of composite materials in application for civil works, providing an alternative that will address issues of durability, cost, and flexibility in infrastructure.
Assessing the Impact of Sustainable Independent Oil Palm Cultivation on Rural Development: A Case Study of Angkola Sangkunur Sub-District, South Tapanuli Regency
Authors: Lubis Arga Abdi Rafiud Darajat , Marpaung Henry
Published: September 2024

This study evaluates the impact of sustainable independent oil palm cultivation on rural development in the Angkola Sangkunur sub-district, South Tapanuli Regency, Indonesia. The research focuses on five key aspects: legal, technical cultivation, environmental management, labor, and institutional factors. Data was collected through a combination of primary and secondary sources, with primary data obtained via questionnaires distributed to a probability-based sample of 165 respondents. The analysis employed multiple linear regression to assess the influence of each aspect on regional development, with hypotheses tested using both F-tests and t-tests. The results reveal that the technical cultivation and institutional aspects exert a significant positive influence on rural development, underscoring the critical role of advanced agricultural practices and strong governance structures. While legal and environmental management aspects also have positive effects, their impact was not statistically significant, indicating that these factors may require further development or longer timeframes to manifest significant outcomes. Conversely, the labor aspect showed a negative but statistically insignificant effect, suggesting that the costs associated with implementing sustainable labor practices may pose challenges for smallholder farmers. This study concludes that enhancing technical capabilities and institutional frameworks offers the most immediate and substantial benefits for rural development in the region. However, a holistic approach that also addresses legal, environmental, and labor issues is essential for achieving long-term sustainability. The findings provide valuable insights for policymakers, stakeholders, and researchers focused on sustainable agriculture and rural development.
THE URGENCY OF ARCHIVISTS AS PROFESSIONALS IN AUTOMATION-BASED ARCHIVES MANAGEMENT
Authors: Ningrum Aisyah Wahyu Kusuma
Published: September 2024

The purpose of this study is to identify and explain the urgency of archivists as professionals who manage archives based on automation. The type of research used is qualitative research which is a literature study using books and other literatures as the main object of this research. In library research, the method used to collect research data is in the form of library data that has been selected, searched, presented and analyzed so that the data presented is in the form of words that are processed to be concise and systematic. The data analysis technique used is a content analysis technique which is a scientific analysis of the essence of a data. The results obtained through this research are that as professional staff, archivists have a very important urgency in automation-based archive management because without competent archivists, automation-based archive management will not be able to run properly. The benefit of carrying out this research is that each agency can further improve the quality of archive management through an automation system with managers who are truly experts in their fields or professional archivists, both archivists who are graduates from universities and archivists who have attended various training/training so that the quality of archive management in These agencies are increasing.
Vi kan skabe sporet sammen
Authors: Lund Breil Louise , Georgsen Marianne , Dau Susanne
Published: September 2024

Artiklen præsenterer og diskuterer et projekt, hvor der arbejdes målrettet med at etablere et ligeværdigt samarbejde mellem underviser og studerende omkring læringsdesignet af de studerendes igangværende uddannelse. Arbejdet med læringsdesign, som her forstås som en metodologi til undervisningsudvikling (jf. Dohn et al., 2019), tager afsæt i Fawns’ formulering af en Entangled Pedagogy, som bl.a. sætter fokus på de studerendes deltagelse i designarbejdet. Med afsæt i poststrukturalismen (Juelskjær & Plauborg, 2013; Søndergaard, 2005; Focault, 2002) analyseres kvalitative, empiriske data (fokusgruppeinterviews) med henblik på at afdække studenterperspektivet på det overordnede forskningsspørgsmål: Hvad kendetegner de studerendes bidrag, når de inviteres til at medudvikle læringsdesignet for deres egen uddannelse? 
Formålet er todelt: Dels at kvalificere vores viden om muligheder og begrænsninger ved at involvere studerende direkte i læringsdesign-processer, og dels at afprøve en udviklings- og analysemetode, som tager et poststrukturalistisk afsæt og sætter fokus på deltagernes fortællinger som centrale i det empiriske materiale. Det konkluderes, at den afprøvede metode til involvering af de studerende i designprocessen er særdeles frugtbar ift. at belyse de studerendes værdier i forbindelse med uddannelsen. Afslutningsvis drøftes metodiske perspektiver ift. en pædagogisk praksis, hvor studerende gennem hele uddannelsesforløbet jf. Fawns inviteres til at tage medansvar for det didaktiske design.
Influence of Ceramic Waste and Cement on the Mechanical and Hydraulic Properties, and Microstructure of the Road Sub-Base Layer
Authors: Deboucha Sadek , Ziani Hocine , Amriou Abderrachid , Maherzi Walid , Deboucha Walid
Published: September 2024

This study examines cement and ceramic waste (CW) for the sub-base layer of roads. This innovative method can do away with the risks associated with improper disposal of industrial waste. To achieve this objective, several proportions of cement and CW were used, ranging from 1.5 to 2% and 5% to 15%, respectively. The aim of the work was to examine the influences of CW and ordinary Portland cement (OPC) on the unconfined compressive strength (UCS), permeability, consolidation, and microstructures of untreated and treated soil of road sub-base layer. The Guelph permeameter, UCS, permeability, and one- dimensional consolidation were among the laboratory and in-situ tests that were examined; the microstructures were characterised using SEM, infrared (IR), and mercury intrusion porosimetry (MIP). The findings indicated that the high permeability of the natural soil caused harm to our road soon after construction. Applying 5 to 15% CW reduced permeability by approximately 100% and settlement by around 43%. Furthermore, under wet and immersed conditions, mixing CW and OPC with soil raised UCS by approximately 182% and 20 times, respectively. This study demonstrated that by enhancing the geotechnical properties of soil, CW and OPC combined with it could be used as a road sub-base layer material.
Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia
Authors: Sun Naidi , Sun Yu-Yo , Cao Rui , Chen Hong-Ru , Wang Yiming , Fugate Elizabeth , Smucker Marchelle R , Kuo Yi-Min , Grant P Ellen , Lindquist Diana M , Kuan Chia-Yi , Hu Song
Published: September 2024

Hypoxia-ischemia (HI), which disrupts the oxygen supply-demand balance in the brain by impairing blood oxygen supply and the cerebral metabolic rate of oxygen (CMRO
2
), is a leading cause of neonatal brain injury. However, it is unclear how post-HI hypothermia helps to restore the balance, as cooling reduces CMRO
2
. Also, how transient HI leads to secondary energy failure (SEF) in neonatal brains remains elusive. Using photoacoustic microscopy, we examined the effects of HI on CMRO
2
in awake 10-day-old mice, supplemented by bioenergetic analysis of purified cortical mitochondria. Our results show that while HI suppresses ipsilateral CMRO
2
, it sparks a prolonged CMRO
2
-surge post-HI, associated with increased mitochondrial oxygen consumption, superoxide emission, and reduced mitochondrial membrane potential necessary for ATP synthesis—indicating oxidative phosphorylation (OXPHOS) uncoupling. Post-HI hypothermia prevents the CMRO
2
-surge by constraining oxygen extraction fraction, reduces mitochondrial oxidative stress, and maintains ATP and N-acetylaspartate levels, resulting in attenuated infarction at 24 hours post-HI. Our findings suggest that OXPHOS-uncoupling induced by the post-HI CMRO
2
-surge underlies SEF and blocking the surge is a key mechanism of hypothermia protection. Also, our study highlights the potential of optical CMRO
2
-measurements for detecting neonatal HI brain injury and guiding the titration of therapeutic hypothermia at the bedside.
A neural network model of differentiation and integration of competing memories
Authors: Ritvo Victoria JH , Nguyen Alex , Turk-Browne Nicholas B , Norman Kenneth A
Published: September 2024

What determines when neural representations of memories move together (integrate) or apart (differentiate)? Classic supervised learning models posit that, when two stimuli predict similar outcomes, their representations should integrate. However, these models have recently been challenged by studies showing that pairing two stimuli with a shared associate can sometimes cause differentiation, depending on the parameters of the study and the brain region being examined. Here, we provide a purely unsupervised neural network model that can explain these and other related findings. The model can exhibit integration or differentiation depending on the amount of activity allowed to spread to competitors — inactive memories are not modified, connections to moderately active competitors are weakened (leading to differentiation), and connections to highly active competitors are strengthened (leading to integration). The model also makes several novel predictions — most importantly, that when differentiation occurs as a result of this unsupervised learning mechanism, it will be rapid and asymmetric, and it will give rise to anticorrelated representations in the region of the brain that is the source of the differentiation. Overall, these modeling results provide a computational explanation for a diverse set of seemingly contradictory empirical findings in the memory literature, as well as new insights into the dynamics at play during learning.
The exchange dynamics of biomolecular condensates
Authors: Zhang Yaojun , Pyo Andrew GT , Kliegman Ross , Jiang Yoyo , Brangwynne Clifford P , Stone Howard A , Wingreen Ned S
Published: September 2024

A hallmark of biomolecular condensates formed via liquid-liquid phase separation is that they dynamically exchange material with their surroundings, and this process can be crucial to condensate function. Intuitively, the rate of exchange can be limited by the flux from the dilute phase or by the mixing speed in the dense phase. Surprisingly, a recent experiment suggests that exchange can also be limited by the dynamics at the droplet interface, implying the existence of an ‘interface resistance’. Here, we first derive an analytical expression for the timescale of condensate material exchange, which clearly conveys the physical factors controlling exchange dynamics. We then utilize sticker-spacer polymer models to show that interface resistance can arise when incident molecules transiently touch the interface without entering the dense phase, i.e., the molecules ‘bounce’ from the interface. Our work provides insight into condensate exchange dynamics, with implications for both natural and synthetic systems.