bluuebunny/crossref_metadata_2025 huggingface dataset:
Da nascente à foz: itinerário crítico para Um rio sem fim (1998), de Verenilde Santos Pereira
Authors: Silva Allison Marcos Leão da , Moreira Luana Aguiar , Páscoa Márcio Leonel Farias Reis
Published: March 2022

No campo dos estudos literários, o acesso à voz e ao poder de representar a si mesmo, no que diz respeito aos grupos marginalizados, como as etnias indígenas, tem sido uma problemática cada vez mais debatida – como em Dalcastagnè (2002) e Olivieri-Godet (2013), por exemplo –, ampliando o que se compreende por representação e representatividade nas artes. Nesse sentido, o presente artigo tem como objetivo analisar o romance Um rio sem fim (1998), da jornalista, indigenista e escritora afro-indígena Verenilde Santos Pereira (1956-), haja vista o processo de criação da obra e as representações das personagens indígenas, sobretudo as femininas. Seja a partir de sua gênese – pois, originalmente, a obra fora parte da dissertação de mestrado da autora – em que se percebe a questão da diferença entre a linguagem literária e acadêmica, seja pelas representações das personagens subalternizadas e as múltiplas violências por elas sofridas, o romance de Verenilde Pereira questiona e reformula os discursos excludentes e eurocêntricos sobre o outro. Observar-se-á, durante as análises, como as concepções da autora sobre alteridade e linguagem influenciam, dessa maneira, na representação dos sujeitos indígenas e na construção de uma narrativa envolvente, polifônica e não-linear.
Implantação da Estratégia e-SUS Atenção Básica: uma análise fundamentada em dados oficiais
Authors: Cielo Ana Claudia , Raiol Tainá , Silva Everton Nunes da , Barreto Jorge Otávio Maia
Published: March 2022

OBJETIVO Analisar a implantação da estratégia e-SUS Atenção Básica (e-SUS AB) no Brasil entre os anos iniciais do sistema, de 2013 até 2019. MÉTODOS Trata-se de um estudo quantitativo, descritivo e exploratório. Foram considerados os dados oficiais do Ministério da Saúde, enviados pelos municípios brasileiros, no período de abril de 2013 a dezembro de 2019. Os municípios foram categorizados como ‘não implantado’, ‘implantação inicial’, ‘implantação parcial’ e ‘implantado’, de acordo com os critérios definidos neste estudo. Verificou-se também se o tipo de município, segundo a classificação do IBGE, influenciou no grau de implantação da estratégia e-SUS AB. Foram realizadas análises descritivas e investigada a associação entre os graus de implantação do e-SUS AB e a tipologia da classificação e caracterização dos espaços rurais e urbanos do IBGE. RESULTADOS O grau de implantação aumentou no período analisado. A situação de implantação da estratégia e-SUS AB, em 2019, foi ‘implantado’ em 20,2% (1.117) dos municípios, ‘implantação parcial’ em 32,9% (1.819), ‘implantação inicial’ 39,1% (2.159) e a situação ‘não implantado’ foi atribuída em 7,8% (432). As regiões Sul e Sudeste apresentaram a melhor situação de implantação em todos os anos e os estados do Rio Grande do Sul, São Paulo e Santa Catarina alcançaram um maior percentual de municípios com a situação ‘implantado’ em 2019. CONCLUSÕES Houve avanço na implantação da estratégia e-SUS AB ao longo dos anos. A maior parte dos municípios encontra-se entre o status ‘implantação inicial’ e ‘implantação parcial’. Com isso, conclui-se que ainda são necessários investimentos em recursos tecnológicos, treinamento de profissionais e suporte para qualificar a implantação e uso de sistemas de informação no país, especialmente para a estratégia e-SUS AB.
Does the presence of conspecifics facilitate exploratory behaviour in a cichlid fish (Etroplus suratensis)?
Authors: Sommer-Trembo C. , Oliver C. , Wolf L. , Garcia C. , Salzburger W.
Published: March 2022

Animals confronted with any kind of novelty show behavioural responses driven by avoidance and exploration. The expression of both tendencies is modulated by anxiety. Especially in group-living animals, the presence of conspecifics can reduce anxiety in novel situations and hence increase exploratory tendency. Such intensified behavioural responses triggered by the social environment of an individual are called social facilitation. Here, we tested for social facilitation on the exploratory tendency of group-living juvenile Green chromide cichlid fish (Etroplus suratensis) by assessing each individual twice in an open field test: once alone and once together with a conspecific. Contrary to our expectations, we found no difference in exploratory behaviour between the groups. However, our results suggest that changes in exploratory tendency across the two treatments were highly individual, both in extent and direction, and are likely driven by the presence of the conspecific and the focal individual’s own behavioural type.
Jan van der Goes
Authors: van den Bel Martijn M.
Published: March 2022

This article tries to demonstrate that the former governor of Essequibo, Jan van der Goes, was also the Indian prince called Vandergoes met by the English, French, and Dutch in the early second half of the seventeenth century at Cayenne. This hypothesis is supported by detailed information on the career of Jan van der Goes derived from the general meetings of the Zeeland Chamber of the WIC and by appearances of the aforementioned Vandergoes in various European documents. In addition, the incorporation of this Dutchman among the Arecarets reveals a particular Amerindian adaptation to colonization along the Wild Coast.
Miracles in Writing: Obstetric Intercessions, Scribal Relics, and Jesuit News in the Early Modern Global Cult of Ignatius of Loyola
Authors: Greenwood Jonathan E.
Published: March 2022

The reputation of Ignatius of Loyola (c.1491–1556), the founder of the Society of Jesus, as a miracle-worker grew during the 1590s, which included his aid in childbirth through handwritten relics. This article examines obstetric miracles associated with Ignatius in the early modern world prior to his canonization in 1622. Through his letters and signature, Ignatius rescued women and their offspring during dangerous and near-fatal deliveries; delayed certain neonatal mortalities long enough for a baptism to occur; and allowed the delivery of a dead fetus to save the mother’s life. While the claims had no bearing on the official declaration of his sainthood, the attributed miracles are emblematic of the concentric and transoceanic nature of his cult. Information and material pathways contributed to the promulgation of the founder’s sanctity in the confines of women in labor and childbirth that had their own patron saints for centuries.
In the Shadow of Francis Xavier: Martyrdom and Colonialism in the Jesuit Asian Missions
Authors: Cañeque Alejandro
Published: March 2022

This article focuses on the violent deaths of the Jesuit missionaries Rodolfo Acquaviva, Marcello Mastrilli, and Diego Luis de San Vítores, who were killed in the course of their evangelical endeavors in India, Japan, and the Mariana Islands, respectively. It elucidates the ways in which the figure of St. Francis Xavier intersected with the Jesuit ideal of martyrdom, while situating the three martyred Jesuits within the history of Iberian imperialism and colonialism. Xavier became the dominant Jesuit image of apostolic sanctity, and he greatly energized the evangelical zeal of many Jesuits, eager to missionize in distant East Asia. At the same time, the Jesuit evangelical impulse in the early modern period became closely intertwined with the desire for martyrdom. In their efforts to create saintly figures of the three slain missionaries, Jesuit authors would establish a special connection between St. Francis Xavier and the martyred Jesuits, Mastrilli and San Vítores being described as almost perfect replicas of the saint, even though Xavier never experienced martyrdom.
Morphological and phylogenetic characterisations reveal nine new species of Chrysosporium (Onygenaceae, Onygenales) in China
Authors: HAN YAN-FENG , GE WEI , ZHANG ZHI-YUAN , LIANG JIAN-DONG , CHEN WAN-HAO , HUANG JIAN-ZHONG , LIANG ZONG-QI
Published: March 2022

Twenty-three strains of Chrysosporium were isolated from soil samples in different provinces of China. Phylogenetic analyses of ITS sequence data showed that these strains comprised nine new species and four already known species. The new species could be also distinguished from related species by their morphology. The results of phylogenetic and morphological analyses confirmed the nine new species of Chrysosporium. Descriptions and illustrations of these new species are provided.
Petrocosmea dejiangensis (Gesneriaceae), a new species from Guizhou, China
Authors: XU JIAN , LI SA , TANG SHENG-HU , REN QI-FEI
Published: March 2022

Southwestern China is the centre of diversity of Petrocosmea (Gesneriaceae). Here, a new species, named Petrocosmea dejiangensis, from north-eastern Guizhou, China, is described. The new species is most similar to P. martini, but it is distinguished from the latter by two dark blue-purple stripes inside the corolla tube along its entire length, the anthers shorter than the filaments, and the stigma apex rounded. Three populations comprising approximately 120 mature individuals were found at and near the type locality. This new taxon was assessed as “Data Deficient” (DD), according to IUCN standards.
Rhanteriopsis baskilensis sp. nov. (Inuleae, Asteraceae), a new species from Turkey
Authors: HAMZAOĞLU ERGİN , BEHÇET LÜTFİ
Published: March 2022

Some interesting Asteraceae specimens were collected from Baskil (Elazığ, Turkey) with palea on its receptaculum, few and flat pappus bristles. After our examination, it was understood that the specimens belonged to Rhanteriopsis, which is a new genus record for Turkey. The specimens are morphologically similar to R. microcephala, which is endemic to Syria, and R. puberula, which is distributed in Iraq and Iran. However, the Turkish specimens differ from these species in its involucral bracts and paleae being narrower, achenes shorter, and pappus bristles 5. In this study, a detailed description of the new species, its morphological comparison with R. microcephala and R. puberula, photographs and some ecological information are given. In addition, an IUCN threat category is proposed for the new species, taking into account the existing and potential threats to its distribution.
Nomenclatural and taxonomic survey of the South American clade of Lobelia section Rhynchopetalum (Campanulaceae)
Authors: ROLLIM ISIS DE MELLO , PERES COELHO GUILHERME , TERESINHA SFOGGIA MIOTTO SILVIA , RICARDO VIEIRA IGANCI JOÃO , TROVÓ LOPES DE OLIVEIRA MARCELO
Published: March 2022

Lobelia is the largest genus within the subfamily Lobelioideae of Campanulaceae, comprising 415 species and ranging from small to exuberant woody herbs. In an attempt to clarify the systematics of Lobelia, a nomenclatural and taxonomic survey of its section Rhynchopetalum for South America is here presented. This group is monophyletic and consists of ten species, whose important distinguishing characters are the robust habit, often woody and pachycaulous, terminal racemes of large sub-bilabiate flowers, with only the ventral anthers bearded, and capsules producing numerous lenticular, commonly winged, seeds with a striate-reticulate testa. Along with a synopsis of the group, an identification key, and a distribution map, we also propose seven lectotypifications (for L. fistulosa, L. glazioviana, L. hassleri, L. hilaireana, L. langeana, L. organensis, and L. uranocoma) and four new synonymizations (for Haynadia organensis var. insignis, L. imperialis, L. imperialis var. kanitzii, and L. stellfeldii).
Toxicodendron oligophyllum (Anacardiaceae), a new species from Fujian, China: evidence from morphological and molecular analyses
Authors: TANG SHU-LING , CHEN XIN-YAN , MA LIANG , NI BI-YONG , PAN BIAO-ZHI , CHEN SHI-PIN
Published: March 2022

A new species of Anacardiaceae, Toxicodendron oligophyllum S. L. Tang, Liang Ma & S. P. Chen, from eastern Fujian Province, China, is described and illustrated. Morphologically, the leaf of T. oligophyllum includes only 3–5 leaflets which is the least number in all known species of Toxicodendron. Additionally, the length of inflorescence equal to which of the leaf can also be used as a well diagnostic characters to distinguish the new species from the other Toxicodendron. The phylogeny of Toxicodendron using the nuclear ribosomal internal transcribed spacer (nrITS) and chloroplast (trnL-F) sequences was reconstructed. The result showed the new species is sister to T. sylvestre (Sieb. & Zucc.) Kuntze.
A Comparison of Land Surface Phenology in the Northern Hemisphere Derived from Satellite Remote Sensing and the Community Land Model
Authors: Li Xiaolu , Melaas Eli , Carrillo Carlos M. , Ault Toby , Richardson Andrew D. , Lawrence Peter , Friedl Mark A. , Seyednasrollah Bijan , Lawrence David M. , Young Adam M.
Published: March 2022

Large-scale changes in the state of the land surface affect the circulation of the atmosphere and the structure and function of ecosystems alike. As global temperatures increase and regional climates change, the timing of key plant phenophase changes are likely to shift as well. Here we evaluate a suite of phenometrics designed to facilitate an “apples to apples” comparison between remote sensing products and climate model output. Specifically, we derive day-of-year (DOY) thresholds of leaf area index (LAI) from both remote sensing and the Community Land Model (CLM) over the Northern Hemisphere. This systematic approach to comparing phenologically relevant variables reveals appreciable differences in both LAI seasonal cycle and spring onset timing between model simulated phenology and satellite records. For example, phenological spring onset in the model occurs on average 30 days later than observed, especially for evergreen plant functional types. The disagreement in phenology can result in a mean bias of approximately 5% of the total estimated Northern Hemisphere NPP. Further, while the more recent version of CLM (v5.0) exhibits seasonal mean LAI values that are in closer agreement with satellite data than its predecessor (CLM4.5), LAI seasonal cycles in CLM5.0 exhibit poorer agreement. Therefore, despite broad improvements for a range of states and fluxes from CLM4.5 to CLM5.0, degradation of plant phenology occurs in CLM5.0. Therefore, any coupling between the land surface and the atmosphere that depends on vegetation state might not be fully captured by the existing generation of the model. We also discuss several avenues for improving the fidelity between observations and model simulations.
LainePoiss®—A Lightweight and Ice-Resistant Wave Buoy
Authors: Alari Victor , Björkqvist Jan-Victor , Kaldvee Valdur , Mölder Kristjan , Rikka Sander , Kask-Korb Anne , Vahter Kaimo , Pärt Siim , Vidjajev Nikon , Tõnisson Hannes
Published: March 2022

Wave buoys are a popular choice for measuring sea surface waves, and there is also an increasing interest for wave information from ice-covered water bodies. Such measurements require cost-effective, easily deployable, and robust devices. We have developed LainePoiss (LP)—an ice-resistant and lightweight wave buoy. It calculates the surface elevation by double integrating the data from the inertial sensors of the microelectromechanical system (MEMS), and transmits wave parameters and spectra in real time over cellular or satellite networks. LP was validated through 1) sensor tests, 2) wave tank experiments, 3) a field validation against a Directional Waverider, 4) an intercomparison of several buoys in the field, and 5) field measurements in the Baltic Sea marginal ice zone. These extensive field and laboratory tests confirmed that LP performed well (e.g., the bias of Hm0 in the field was 0.01 m, with a correlation of 0.99 and a scatter index of 8%; the mean absolute deviation of mean wave direction was 7°). LP was also deployed with an unmanned aerial vehicle and we present our experience of such operations. One issue that requires further development is the presence of low-frequency artifacts caused by the dynamic noise of the gyroscope. For now, a correction method is presented to deal with the noise.

Significance Statement

Operational wave buoys are large and therefore expensive and inconvenient to deploy. Many commercially available devices cannot measure short waves and are not tested in ice. Our purpose was to develop an affordable wave buoy that is lightweight, ice resistant, capable of measuring short waves, and also has a longer operating life than existing research buoys. The buoy is easily deployed with a small boat or even an industrial drone, thus reducing operating costs. The buoy is accurate, and captures waves that are too short for operational wave buoys. This is relevant for coastal planning in, e.g., archipelagos and narrow fjords. We measured waves in ice in the Baltic Sea, and are planning to extend these measurements to Antarctica.
Desmond Mpilo Tutu and the transfiguration of the Anglican pastoral imagination
Authors: Kujawa-Holbrook Sheryl A.
Published: March 2022

Discourse on the Anglican pastoral imagination is most closely associated with the English church and theologians from Britain and North America. This article argues that the theology and practice of Desmond Mpilo Tutu transformed the traditional attributes of the Anglican pastoral imagination for a postcolonial age when most Anglicans live in the Global South. Tutu’s expression of the Anglican pastoral imagination draws upon the richness of the biblical image of the Transfiguration and expands the Anglican heritage from a South African context. If Anglicanism is indeed a living tradition, then our pastoral imagination must be forged from a dialogue between the wisdom of the past and the voices of the present, like Desmond Mpilo Tutu. The themes which illuminate the Anglican pastoral imagination tradition are authentic love, the incarnation, prayer and sacrament, and a church for the world.
Agent Transparency, Situation Awareness, Mental Workload, and Operator Performance: A Systematic Literature Review
Authors: van de Merwe Koen , Mallam Steven , Nazir Salman
Published: March 2022

Objective

In this review, we investigate the relationship between agent transparency, Situation Awareness, mental workload, and operator performance for safety critical domains.

Background

The advancement of highly sophisticated automation across safety critical domains poses a challenge for effective human oversight. Automation transparency is a design principle that could support humans by making the automation’s inner workings observable (i.e., “seeing-into”). However, experimental support for this has not been systematically documented to date.

Method

Based on the PRISMA method, a broad and systematic search of the literature was performed focusing on identifying empirical research investigating the effect of transparency on central Human Factors variables.

Results

Our final sample consisted of 17 experimental studies that investigated transparency in a controlled setting. The studies typically employed three human-automation interaction types: responding to agent-generated proposals, supervisory control of agents, and monitoring only. There is an overall trend in the data pointing towards a beneficial effect of transparency. However, the data reveals variations in Situation Awareness, mental workload, and operator performance for specific tasks, agent-types, and level of integration of transparency information in primary task displays.

Conclusion

Our data suggests a promising effect of automation transparency on Situation Awareness and operator performance, without the cost of added mental workload, for instances where humans respond to agent-generated proposals and where humans have a supervisory role.

Application

Strategies to improve human performance when interacting with intelligent agents should focus on allowing humans to see into its information processing stages, considering the integration of information in existing Human Machine Interface solutions.
Textile-based directionally antagonistic sound absorber with double gradient structure
Authors: Zhang Chunchun , Li Huiqin , Gong Jixian , Chen Jiahao , Li Zheng , Li Qiujin , Cheng Meilin , Zhang Jianfei
Published: March 2022

In the structural design of sound-absorbing materials, how to combine the merits of porous materials with acoustic functional fillers with special structures to improve the sound-absorbing performance of porous materials at low-medium frequencies is a challenging problem. Herein, a directionally antagonistic acoustic textile is proposed as a sound absorber fabricated via single-sided coating. It is found that the sound absorber presents a double gradient structure by controlling the distribution of filler on the porous material frame. Considering the incident plane of acoustic waves, two different paths are defined, namely A–B and B–A (A, coated side; B, uncoated side), under which the sound absorber shows remarkable anisotropic sound absorption. The peak frequency is from 5559 Hz of bare fabric to 3455 Hz of the A–B NWIII (coated nonwoven when sound waves propagate along A–B) sound absorber, showing a significant tendency to move to the lower frequencies. The peak value of sound absorption coefficient of the A–B NWIII is 0.94, indicating a high sound absorptivity. In addition, by adjusting the acoustic functional filler and weaving structure and thickness of the base fabric, the sound absorber exhibits the expected anisotropic sound absorption. The novel sound absorber can be fit for lightweight sound-absorbing applications because of the characteristics of light, soft, high efficiency and broadband sound absorption.
The use of case study analysis in public affairs education: Linking theory and practice
Authors: Powell David C
Published: March 2022

Case study analysis has been used for many years across a variety of disciplines. One of the primary advantages of case study analysis is its ability to illustrate the nexus between theory and practice. This paper explores the use of case study analysis as a culminating experience in a large Master of Public Administration (MPA) program in the western United States. Case studies are examined using an established approach to determine the type, structure, and source of these cases. The project also examines alumni perspectives regarding the utility of case studies relative to their careers.
Urgent-start peritoneal dialysis: Association with outcomes
Authors: Karpinski Steph , Sibbel Scott , Cohen Dena E , Colson Carey , Van Wyck David B , Ghaffari Arshia , Schreiber Martin J , Brunelli Steven M. , Tentori Francesca
Published: March 2022

The majority of end-stage kidney disease (ESKD) patients start dialysis without adequate pre-dialysis planning. Of these patients, the vast majority initiate in-centre haemodialysis using a central venous catheter (ICHD-CVC). A minority utilise urgent-start peritoneal dialysis (USPD), whereby a peritoneal dialysis catheter is placed and used for dialysis without the usual 2–4-week waiting period. In this multicentre, retrospective study of adult patients initiating dialysis during 2018, we compared outcomes among patients utilising these two dialysis initiation routes. Patients who initiated dialysis via ICHD-CVC were matched 1:1 to patients who utilised USPD on the basis of aetiology of ESKD, race, diabetes status and insurance type. Hospitalisation and mortality were evaluated from dialysis initiation through the first of death, transplant, loss to follow-up or study end (30 June 2019). Outcomes were compared using models adjusted for age and sex. A total of 717 USPD patients were matched to ICHD-CVC patients. During follow-up, USPD patients were hospitalised at a rate of 1.21 admissions/patient-year (pt-yr) versus 1.51 admissions/pt-yr for ICHD-CVC. This corresponded to a 24% lower rate of hospitalisation among USPD patients (adjusted incidence rate ratio 0.76, 95% confidence interval [CI] 0.65–0.88). Mortality rates were 0.08 and 0.11 deaths/pt-yr among USPD patients and ICHD-CVC patients, respectively (adjusted hazard ratio 0.84, 95% CI 0.62, 1.15). These findings suggest that more widespread adoption of USPD may be beneficial among patients with limited pre-dialysis planning.
Transformation of the Colombian Radio in the Informative Sonosphere of the SARS-CoV-2
Authors: Barrios-Rubio Andrés
Published: March 2022

Changes experienced by the social environment because of the SARS-CoV-2 established a new roadmap in the news agenda that addresses the radio industry, convergence of sound semiotics with textual and visual elements to explore new narratives, and meet the needs of an audience focused on screen devices. Adaptation of the radio medium to the digital sonosphere of the audience invites to focus the attention of researchers on the transformation of productive routines in the context of the pandemic, and the analysis of the communicative content that is used to capture the attention of the public. This research took as the focus of study the five Colombian generalist stations, with national coverage—Caracol Radio, W Radio, Blu Radio, RCN Radio and La FM–through a mixed methodology; observation of journalistic coverage broadcast on the air, web-radio and digital platforms, a quantitative input that is contrasted with the qualitative analysis of the messages and the approach of the radio agents. Exploration of the investigative corpus warns of the presence of new styles, formats and narratives that bet on the interaction with the listener/user in the smartphone; journalistic work constituted by the principle of topicality and immediacy that is permeated by technological resources in the context offline and online. Technological innovation has imposed new forms of consumption whose logics no longer correspond to the analogue system of production, distribution and consumption of information; the normalisation of connectivity, ubiquity, timelessness and interactivity are values today inherent in the content broadcasted by radio.
Representations of race/ethnicity and the nation: A content analysis of televised Polish international football
Authors: van Lienden Arne , van Sterkenburg Jacco
Published: March 2022

This study explores the meanings given to race/ethnicity by Polish commentators covering games of the Polish national football team on TV. There will be an explicit focus on how such patterns of representation might intersect with those given to national identities in the context of international football. Our analysis reveals that commentators habitually reproduce the racialized stereotype of the ‘natural Black athlete’, particularly in the representation of Black African football players. White players remain more ‘invisible’ in the commentary, yet also here the intersection with national or wider regional backgrounds inflects the patterns of representation. For instance, White Portuguese and White Bosnian players are represented in a fashion that suggests they are placed outside of hegemonic Polish understandings of White (sporting) masculinity. This reveals the contingency and complexity of discourses of Whiteness in the Polish context. The findings reveal that the normativity of European Whiteness is also reflected in the meanings given to Polishness by the commentators, which are imbued with notions of psychological (masculine) Whiteness.
Unclassified Oncocytic Renal Neoplasm with Rib and Liver Metastases: Metastatic Oncocytoma?
Authors: Tomaszewski Zoe , Littler Yvonne
Published: March 2022

Renal tumors with oncocytic or chromophobe-like morphology can be a common source of diagnostic difficulty. In some series, they constitute the largest group of unclassified renal cell carcinomas, a term used for neoplasms that do not fit the current classification of renal tumors. We describe the histological, immunohistochemical, and molecular findings of an eosinophilic renal neoplasm which presented with rib and liver metastases, and provide a review of the literature. The possibility of a renal oncocytoma with metastases was initially considered but excluded on the basis of several morphological and immunohistochemical features. Additionally, the tumor did not correspond with other traditional or newly emerging categories of renal neoplasms. It was therefore regarded as an unclassified oncocytic renal neoplasm which demonstrated evidence of malignant potential due to the presence of multiple metastases.
The Bifactor Structure of the Emotion Expression Scale for Children in a Sample of School-Aged Portuguese Children
Authors: Caiado Brígida , Canavarro Maria Cristina , Moreira Helena
Published: March 2022

The Emotion Expression Scale for Children (EESC) is a 16-item self-report questionnaire assessing children’s difficulties in emotion expression (i.e., poor emotion awareness and reluctance to express emotions). Considering the inconsistent findings regarding its factorial structure and dimensionality, this study aims to explore the factor structure and psychometric properties of the EESC in a sample of 286 Portuguese children (8–12 years). Three competing models were analyzed through confirmatory factor analysis (correlated two-factor model, one-factor model, and bifactor model). The bifactor model provided a better fit than the competing models, and the results suggested a strong general factor of “difficulties in emotion expression.” The validity of the EESC was also indicated by its positive correlations with variables assessing child anxiety, depression, and behavioral avoidance and its negative correlation with mindfulness skills. The EESC is a valid measure of children’s difficulties in emotion expression and the use of its total score is recommended.
Expanding oncology pharmacist teams: Justifying the return on investment
Authors: Mahmoudjafari Zahra , Hough Shannon
Published: March 2022

Oncology pharmacists are an integral member of the cancer care multi-disciplinary team. Despite the role being previously well defined, responsibilities continue to expand. Position justification for pharmacists is a challenge with prerequisites to optimize efficient processes, promote quality and reduce overall costs. Initiation and implementation of new oncology pharmacist services requires a clear description of value to the organization and a strong understanding of workflows. Position justifications must be data-driven and unique to the organization's need and should include physician or key stakeholder support, quality initiatives, cost-savings initiatives, and revenue-generating roles. The cases and examples described serve as a reference for individuals, teams, or organizations pursuing the value of a financial investment of an oncology pharmacist to expand or initiate new pharmacy services.
Trans architecture and the prison as archive: “don’t be a queen and you won’t be arrested”
Authors: Sanders Tait , Gildersleeve Jessica , Halliwell Sherree , du Plessis Carol , Clark Kirsty A , Hughto Jaclyn MW , Mullens Amy B , Phillips Tania M , Daken Kirstie , Brömdal Annette
Published: March 2022

Most incarceration settings around the world are governed by strong cisnormative policies, architectures, and social expectations that segregate according to a person's legal gender (i.e. male or female). This paper draws on the lived experiences of 24 formerly incarcerated trans women in Australia and the U.S. to elucidate the way in which the prison functions according to Lucas Crawford's theory of trans architecture, alongside Jacques Derrida's notion of archive fever. The paper displays how the cisnormative archive of the justice system and its architectural constructs impact trans women in men's incarceration settings, including how trans women entering the incarceration setting are able to embody gender in a way that is not reified by the insistences of those normative structures. In light of this, this paper advances a theoretical understanding of the prison as an archive and as an architectural construct, providing a new means of understanding how incarcerated trans persons may use and perform gender to survive carceral violence.
Enhancing post‐COVID-19 work resilience in hospitality: A micro-level crisis management framework
Authors: Lai Yi-Ling , Cai Wenjie
Published: March 2022

COVID-19 has led to immense impacts on the hospitality sector, putting millions of jobs at risk. The uncertainty has resulted in significant psychological effects on service staff. Developing on micro-level interpersonal interactions between line managers and service staff, this article aims to propose a bottom-up approach to alleviate service staff’s anxiety and enhance their work resilience during and after the pandemic. The proposed conceptual framework synthesised the personal uncertainty constructs, self-determination theory (SDT) and leader-member exchange (LMX) to address the psychological issues that emerged from a prolonged ambiguous and unsettled period. The framework proposes that interpersonal exchanges at the micro-level can strengthen service staff’s intrinsic motivation and resilience. This article offers new insights into crisis management research and practice in the hospitality sector by developing a people-centred approach. At the micro-level, this framework offers a holistic strategy, including a flat team structure, uncertainty-embracing organisational environment, transparent decision-making process and sympathetic behaviours from leaders to facilitate service staff to develop greater coping mechanisms for the unknown future. Furthermore, this framework provides organisations preliminary guidelines to establish a longitudinal preventive strategy to strengthen employees’ work resilience.
The reliability and validity of mobalytics proving ground as a perceptual-motor skill assessment for esports
Authors: Pluss Matthew A. , Novak Andrew R , Bennett Kyle J.M. , Panchuk Derek , Coutts Aaron J , Fransen Job
Published: March 2022

This study aimed to investigate the test-retest reliability and discriminant validity of the Mobalytics Proving Ground™ assessment for League of Legends. Forty participants (age: 24.15 ± 3.68 y, sex: male = 31, female = 9) were a priori classified into two expertise groups: (1) esports players (age: 22.98 ± 3.64 y, sex: male = 18, female = 2), and (2) controls (age: 25.31 ± 3.42 y, sex: male = 13, female = 7). Participants completed three separate trials (60 s each) online. To assess test-retest reliability, variables displaying normal distributions were analysed using intraclass correlation coefficient (ICC) estimates for two-way mixed-effects models with 95% confidence intervals. The average ICC for all the independent variables in the esports group and control group were moderate (ICC esports = 0.53 and ICC control = 0.72). The average 95% confidence intervals for the independent variables in the esports and control group were ICC = 0.30–0.75 and ICC = 0.55–0.86, respectively. A Friedman test revealed an effect size of 0.11 in the esports group and 0.07 in the control group. In terms of discriminant validity, there were significant differences for 17 variables when comparing the best scores of each group. Overall, the Mobalytics Proving Ground™ assessment used in the current study can, to some extent, distinguish esports players from controls.
Serum CD40L, ST2, IL-6, and CRP serving as biomarkers for acute coronary syndrome
Authors: Zhu Li , Zhang Chuanmeng , Mao Guangyao , Xu Jie , Qian Jingyu , Jiang Lin , Ye Jun
Published: March 2022

To analyze the diagnostic value of CD40 ligand (CD40L), soluble growth stimulating expression gene 2 protein (ST2), interleukin-6 (IL-6), and C-reactive protein (CRP) are used in patients with acute coronary syndrome (ACS). Serum samples were collected from 259 ACS patients admitted to our hospital. Additionally, 119 healthy individuals who received physical examination in the hospital at the same time period were included as normal control. The levels of CD40L, ST2, IL-6, and CRP in 259 patients with ACS and 119 healthy subjects were detected by ELISA. The levels of CD40L, ST2, IL-6, and CRP were significantly increased in unstable angina (UA) patients, while ST2, CRP, and IL-6 were significantly elevated in acute myocardial infarction (AMI) patients. Pearson correlation analysis showed that ST2 was also closely related to CRP in ACS patients, while ST2 was positively correlated with creatine kinase (CK), creatine kinase isoenzyme (CK-MB), and troponin I (cTnI) in AMI patients. The levels of glucose (GLU) and low-density lipoprotein cholesterol (LDL-c) were significantly decreased, while the levels of high-density lipoprotein cholesterol (HDL-c) were significantly increased in AMI patients treated with stent implantation. Furthermore, the level of serum CD40 L was significantly elevated in coronary heart disease (CHD) patients treated with stent implantation, while the levels of ST2 and IL-6 in AMI patients treated with the stent implantation decreased significantly. The levels of inflammatory factors significantly changed in patients with ACS. These inflammatory factors may involve in the pathological progression of ACS and can be used as diagnostic indexes for ACS.
Incidence and Cost of Surgical Site Infections After Osteochondral Allograft Transplantation and Meniscal Allograft Transplantation in the Knee
Authors: Rucinski Kylee , Stannard James P. , Leary Emily V. , Cook James L.
Published: March 2022

Background:

Surgical site infections (SSIs) significantly influence outcomes and health care costs after orthopaedic surgery, but they have not been well characterized for osteochondral allograft (OCA) transplantation with or without meniscal allograft transplantation (MAT).

Purpose:

To characterize the incidence, cost, and risk factors associated with potential or confirmed SSIs after large single-surface, multisurface, or bipolar allograft transplantation in the knee.

Study Design:

Case-control study; Level of evidence, 3.

Methods:

Prospectively collected registry data were analyzed for patients who underwent primary or revision OCA transplantation with or without MAT in the knee. The Centers for Disease Control and Prevention (CDC) guidelines were used to define SSIs and calculate the SSI incidence. Both potential and confirmed SSIs were analyzed to determine related treatment methods, calculate associated health care costs, and characterize risk factors based on the OCA surgery type (single-surface, multisurface, bipolar, ±MAT), American Society of Anesthesiologists physical status classification system, surgery duration, length of stay, age, sex, body mass index (BMI), and current tobacco use.

Results:

A total of 224 patients were included in the analysis. There were 2 SSIs in 1 patient that met CDC criteria, such that the incidence for this patient population was 0.9%. An additional 7 patients (3.1%) were examined for potential infections not classified as SSIs. Patients with potential or confirmed SSIs had a significantly higher mean BMI compared to patients with no evidence of an SSI ( P <.001). BMI >35 (odds ratio, 9.1) and tobacco use (odds ratio, 6.6) were associated with greater odds for a potential or confirmed SSI. The mean health care costs were $6101 for patients who required additional emergency room visits and/or irrigation and debridement within 90 days postoperatively for potential or confirmed SSIs, $19 for patients with potential superficial incisional SSIs, and $12,100 for patients who experienced a potential or confirmed deep incisional or organ/space SSI >90 days from surgery.

Conclusion:

Large OCA transplantation with and without MAT were associated with a low incidence of confirmed SSIs (0.9%), and patients with BMI >35 and current tobacco use had greater odds of an SSI. Potential and confirmed SSIs were associated with unscheduled appointments, additional surgical procedures, and higher costs.
Healthcare-related infections within nursing homes (NHS): A qualitative study of care practices based on a systemic approach
Authors: Lefosse Giulia , Rasero Laura , Bellandi Tommaso , Sousa Paulo
Published: March 2022

Background

Infectious events, often related to healthcare practice, occur frequently within Nursing Homes (NHs), representing one of the main causes for morbidity, hospital admissions and mortality. The aims of this study are the analysis of care delivery problems and contributory factors of healthcare-related infections in a sample of NHs. This research could help identify organizational, technological and behavioural aspects, to implement improvement actions and reduce the impact of infections in long-term care.

Methods

The study is a qualitative research with a systemic approach, based on the analysis of interactions in real practice between human factors, technologies and organizational structure and processes in 7 NHs in Tuscany (Italy), through extensive and structured observations of daily practices. The collected data were analyzed by applying clinical and ergonomic competences, comparing the data collected with established safe practices. The study was conducted by a nurse and a psychologist

Results

From the data several problems related to infection control emerge. Buildings are often not suitable for confined spaces, room ventilation, natural light and rapid emergency response. Hand washing is not sufficient, use of antibiotics is usually not adequate. The microclimate is often not adequate, hygienic procedures are not always flawless. Staff members are in small numbers.

Discussions

This study highlights high risk of contracting infections related to NHs. The study shows that dedicated infection prevention guidance are needed, to develop a local plan integrated with hospital setting, customized to needs of guests and characteristics of long-term care facilities, supported by a deep understanding of daily practices.
Mouse aortic biomechanics are affected by short-term defective autophagy in vascular smooth muscle cells
Authors: De Munck Dorien G. , Leloup Arthur J. A. , De Moudt Sofie , De Meyer Guido R. Y. , Martinet Wim , Fransen Paul
Published: March 2022

The physiology of vascular smooth muscle (VSMC) cells is affected by autophagy, a catabolic cellular mechanism responsible for nutrient recycling. Autophagy-inducing compounds may reverse arterial stiffening, whereas congenital VSMC-specific autophagy deficiency promotes arterial stiffening. The elevated aortic stiffness in 3.5-month-old C57Bl/6 mice, in which the essential autophagy-related gene Atg7 was specifically deleted in the VSMCs (Atg7F/F SM22α-Cre+ mice) was mainly due to passive aortic wall remodeling. The present study investigated whether aortic stiffness was also modulated by a shorter duration of autophagy deficiency. Therefore, aortic segments of 2-month-old Atg7F/F SM22α-Cre+ mice were studied. Similarly to the older mice, autophagy deficiency in VSMCs promoted aortic stiffening by elastin degradation and elastin breaks, and increased the expression of the calcium binding protein S100A4 (+ 157%), the aortic wall thickness (+ 27%), the sensitivity of the VSMCs to depolarization and the contribution of VGCC mediated Ca2+ influx to α1 adrenergic contractions. Hence, all these phenomena occurred before the age of 2 months. When compared to autophagy deficiency in VSMCs at 3.5 months, shorter term autophagy deficiency led to higher segment diameter at 80 mmHg (+ 7% versus − 2%), normal baseline tonus (versus increased), unchanged IP3-mediated phasic contractions (versus enhanced), and enhanced endothelial cell function (versus normal). Overall, and because in vivo cardiac parameters or aortic pulse wave velocity were not affected, these observations indicate that congenital autophagy deficiency in VSMCs of Atg7F/F SM22α-Cre+ mice initiates compensatory mechanisms to maintain circulatory homeostasis.
The cellular response to drug perturbation is limited: comparison of large-scale chemogenomic fitness signatures
Authors: Barazandeh Marjan , Kriti Divya , Nislow Corey , Giaever Guri
Published: March 2022

Background

Chemogenomic profiling is a powerful approach for understanding the genome-wide cellular response to small molecules. First developed in Saccharomyces cerevisiae, chemogenomic screens provide direct, unbiased identification of drug target candidates as well as genes required for drug resistance. While many laboratories have performed chemogenomic fitness assays, few have been assessed for reproducibility and accuracy. Here we analyze the two largest independent yeast chemogenomic datasets comprising over 35 million gene-drug interactions and more than 6000 unique chemogenomic profiles; the first from our own academic laboratory (HIPLAB) and the second from the Novartis Institute of Biomedical Research (NIBR).

Results

Despite substantial differences in experimental and analytical pipelines, the combined datasets revealed robust chemogenomic response signatures, characterized by gene signatures, enrichment for biological processes and mechanisms of drug action. We previously reported that the cellular response to small molecules is limited and can be described by a network of 45 chemogenomic signatures. In the present study, we show that the majority of these signatures (66%) are also found in the companion dataset, providing further support for their biological relevance as conserved systems-level, small molecule response systems.

Conclusions

Our results demonstrate the robustness of chemogenomic fitness profiling in yeast, while offering guidelines for performing other high-dimensional comparisons including parallel CRISPR screens in mammalian cells.
CAD gene and early infantile epileptic encephalopathy-50; three Iranian deceased patients and a novel mutation: case report
Authors: Yarahmadi Sepideh Gholami , Morovvati Saeid
Published: March 2022

Background

Early infantile epileptic encephalopathy is a severe form of epilepsy that is genetically extremely heterogeneous and characterized by seizures or spasms at the beginning of infancy. Homozygous or compound heterozygous mutation in the CAD gene cause early infantile epileptic encephalopathy-50 (EIEE50). This case report describes the clinical and molecular features of three patients affected with early infantile epileptic encephalopathy.

Case presentation

In this report, we describe the clinical features of two deceased daughters and one recently deceased son affected with seizure, muscular hypotonia, and developmental delay. After genetic counseling, blood samples were obtained from the parents, and whole-exome sequencing was performed. Genomic DNA was extracted from whole blood, and mutation analysis was performed using PCR and sequencing methods for the CAD gene. Genetic analysis using the whole-exome sequencing method has detected a novel likely pathogenic mutation on CAD gene, c.2995G > A (p.Val999Met), in heterozygous states in asymptomatic parents and homozygous state in affected newborn son. This mutation has not been reported in the literature for its pathogenicity.

Conclusions

The asymptomatic parents are carriers for the likely pathogenic variant in the CAD gene, and the recently deceased newborn son had the same mutation in a homozygous state. Given that, multiple lines of in silico computational analysis support the detrimental impact of the variant on the gene, and this variant is absent in population databases. Pathogenic mutations in the CAD gene are related to autosomal recessive EIEE50 with similar signs and symptoms to our patients. Ultimately, it is confirmed that this mutation is causative in our patients.