bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH TERAPI MODELING PARTISIPAN TERHADAP KEPATUHAN MINUM OBAT PADA KLIEN SKIZOFRENIA DI RUMAH SAKIT JIWA DAERAH PROVINSI JAMBI TAHUN 2018
Authors: Nengsih Novida
Published: October 2019

Ketidakpatuhan pasien dalam menjalani pengobatan merupakan salah satu penyebab kekambuhan yang dialami pasien. Hal ini mengakibatkan pengobatan menjadi semakin sulit dan akhirnya akan menghantarkan pada keadaan  kronis berkepanjangan. Terapi modeling partisipanmerupakan suatu strategi yang digunakan dalam membentuk perilaku baru, meningkatkan atau meminimalkan perilaku yang dihindari. Penelitian ini bertujuan mengetahui pengaruh terapi modeling partisipan terhadap kepatuhan minum obat pada klien skizofrenia. Desain penelitian pretest - posttest with control group design. Sampel 112 klien skizofrenia yang terdiri dari 56 kelompok intervensi dan 56 kelompok kontrol. Hasil uji statistik paired sample t test didapatkan nilainya p <0.05). Ada pengaruh terapi Modeling Partisipan terhadap kepatuhan minum obat pasien skizofrenia dengan nilai p = 0,000. Perawat hendaknya menjadikan terapi modeling partisipan sebagai salah satu terapi keperawatan dalam mengatasi masalah   ketidakpatuhan minum obat pada pasien skizofrenia.
HUBUNGAN KADAR TROMBOSIT IBU TERHADAP KEJADIAN PREEKLAMPSIA DI RUMAH SAKIT UMUM DAERAH RADEN MATTAHER PROVINSI JAMBI
Authors: Kurnia pratama Rini Mustikasari
Published: October 2019

Preeklampsia adalah penyebab utama mortalitas dan morbiditas ibu dan janin. Preeklampsia adalah sindrom yang ditandai dengan hipertensi dan proteinuria yang timbul setelah 20 minggu kehamilan. Penyebab kematian ibu sebagian besar disebabkan karena perdarahan, preeklampsia, komplikasi abortus, partus macet dan sepsis. Preeklampsia merupakan penyebab nomor dua, yaitu sebanyak 13% kematian ibu.

Tujuan penelitian ini adalah untuk mengetahui adanya hubungan kadar trombosit ibu terhadap kejadian preeklampsia di RSUD Raden Mattaher Provinsi Jambi. Penelitian ini menggunakan desain penelitian  case-control dengan pendekatan  Retrospektive. Populasi dalam penelitian ini adalah seluruh ibu hamil yang mengalami preeklampsia sebesar 55 responden untuk kasus dan 55 responden  untuk kontrol di RSUD Raden Mattaher Provinsi Jambi Tahun 2017. Teknik pengambilan sampel menggunakan total sampling, Analisis data menggunakan chi-square untuk mengetahui hubungan kadar trombosit ibu terhadap kejadian preeklampsia.

Hasil penelitian yang telah dilakukan didapatkan bahwa ibu yang mengalami preeklampsia sebagian besar memiliki kadar trombosit yang berisiko (55,5%), dan kadar trombosit yang  tidak berisiko (44,5%). Hasil uji statistik chi-square  diperoleh nilai p-value 0,002 (p<0,05) disimpulkan bahwa terdapat hubungan kadar trombosit ibu terhadap kejadian preeklampsia, dengan nilai (OR) 3,656  (1,654 - 8.084).

Kesimpulan penelitian ini adalah terdapat hubungan kadar trombosit ibu terhadap kejadian preeklampsia.
HUBUNGAN ASUPAN GIZI, TINGGI FUNDUS UTERI DAN SOSIAL EKONOMI DENGAN BERAT BAYI LAHIR
Authors: Aghadiati Faradina
Published: October 2019

Berat bayi lahir (BBL) merupakan salah satu indikator kesehatan bayi baru lahir yang sehat dan cukup bulan. Salah satu faktor yang mempengaruhi berat bayi lahir adalah asupan zat gizi dan tinggi fundus uteri, tingkat pendidikan ibu dan, status ekonomi. Asupan gizi yang kurang akibat kekurangan energi dan protein dapat mempengaruhi pertumbuhan linier bayi selama dalam kandungan. Tujuan penelitian adalah menganalisis hubungan asupan energi, protein, tinggi fundus uteri, tingkat pendidikan ibu dan status ekonomi dengan berat bayi lahir. Metode yang digunakan dalam penelitian ini adalah observasional analitik dengan menggunakan  pendekatan cross sectional. Sampel pada penelitian ini adalah 114 ibu hamil yang bertempat tinggal di Kota Yogyakarta. Hasil uji statistik membuktikan ada hubungan yang signifikan antara asupan energi, protein dan tinggi fundus uteri dengan berat bayi lahir  (p < 0.05). Tidak ada hubungan yang signifikan tingkat pendidikan ibu dan status ekonomi dengan bayi lahir (p > 0.05). Kesimpulan penelitian bahwa ibu hamil dengan asupan energi, protein cukup dan tinggi fundus normal cenderung melahirkan bayi dengan berat lahir normal. Tingkat pendidikan ibu dan status ekonomi belum tentu mempengaruhi berat bayi lahir.
Faktor-faktor yang mempengaruhi mutu layanan terhadap kepuasan pasien di Ruang Rawat Jalan RS Royal Prima Jambi Tahun 2018
Authors: Cahya Septian Dwi , Girsang Ermi , Nasution Subang Aini
Published: October 2019

Pelayanan kesehatan yang berkualitas adalah pelayanan kesehatan yang dapat memuaskan setiap pemakai jasa pelayanan kesehatan sesuai dengan tingkat kepuasan rata-rata penduduk serta penyelenggaraannya sesuai dengan kode etik dan standar pelayanan profesi yang ada. Agar pelayanan kesehatan yang diinginkan harus memenuhi syarat-syarat yang mencakup ketersedian (available), wajar (appropriate), berkesinambungan (continue), dapat diterima (acceptable), dapat dicapai (accessible), dapat dijangkau (affordable), effisien (efficient), serta bermutu (quality).

Penelitian ini bertujuan untuk mengetahui factor-faktor yang mempengaruhi mutu layanan terhadap kepuasan pasien di Ruang Rawat Jalan RS Royal Prima Jambi Tahun 2018. Penelitian ini merupakan penelitian kuantitatif, pendekatan yang dipakai dalam peneltian ini adalah penelitian survey (non eksperimen) dengan desain penelitian yang digunakan adalah Survey Cross Sectional. Sampel dalam penelitian ini adalah pasien yang berobat di RS Royal Prima sebanyak 96 responden. Data dianalisis dengan melakukan uji analisis chi-square.

Hasil penelitian ini didapatkan ada hubungan yang bermakna antara reability, assurance, tangible, emphaty dan responsiveness terhadap kepuasan pasien di Ruang Rawat Jalan RS Royal Prima Jambi Tahun 2018. Secara bersama-sama variabel yang berpengaruh terhadap kepuasan pasien adalah tangible Exp (B) = 1,806, p : 0,299 dan responsiveness Exp (B) = 1,246), p : 0,708. yang berarti besar resiko menimbulkan ketidakpuasan adalah 1,806 kali pada variabel tangible dan 1,246 kali pada variabel responsiveness. Untuk meningkatkan kepuasan pasien maka perlu perbaikan tangible dan responsiveness secara bersama-sama.

Untuk itu, perlu dilakukan mengaktifkan pengawasan oleh tim keperawatan, mengedepankan keramahan, bersikap sabar dalam menghadapi/menanggapi keluhan pasien. mengikutkan petugas dalam pelatihan-pelatiahn seperti penguasaan komunikasi terapeutik, costumer servis dan pemberian reward atau punishment, menyediakan ruang tunggu, pengadaan alat-alat kebutuhan dasar pasien, penempatan petugas khusus ruangan yang bertugas membersihkan serta mengawasi kebersihan ruang rawat jalan,
Hubungan Mutu Pelayanan Kesehatan Dengan Kepuasan Pasien Bpjs Rawat Inap Di Rumah Sakit Santa Elisabeth Medan Tahun 2019
Authors: Simalango Andri
Published: October 2019

Mutu pelayanan kesehatan akan dirasakan berkualitas oleh para pelanggannya jika penyampaiannya dirasakan melebihi harapan para pengguna layanan. Penilaian para pengguna jasa pelayanan ditujukan kepada penyampaian jasa, kualitas pelayanan, atau cara penyampaian jasa tersebut kepada para pemakai jasa. Kualitas jasa pelayanan sangat ditentukan apabila kebutuhan para pengguna jasa bisa terpenuhi dan diterima tepat waktu.Tujuan Penelitian Untuk mengetahui Hubungan Mutu Pelayanan Kesehatan Dengan Kepuasan Pasien BPJS Rawat Inap Di Rumah Sakit Santa Elisabeth Medan. Metode penelitian yang digunakan adalah kuantitatif dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah pasien BPJS rawat inap di Rumah Sakit Santa Elisabeth Medan dengan jumlah sampel 85 orang. Analisis data menggunakan uji chi square dengan α<0,05. Hasil Penelitian Menunjukkan bahwa nilai p-value antara Bukti Fisik (p-value 0,013), Kehandalan (p-value 0,002), Daya Tanggap (p-value 0,023), Jaminan (p-value 1,000) dan empati (p-value 0,110) terhadap Kepuasan Pasien BPJS Rawat Inap DI Rumah Sakit Santa Elisabeth Medan. Kesimplan penelitian ini Terdapat hubungan yang bermakna antara Bukti fisik, kehandalan, daya tanggap terhadap kepuasan pasien BPJS Rawat Inap di Rumah Sakit Santa Elisabeth Medan dan terdapat tidak ada hubungan yang bermakna antara jaminan dan empati terhadap kepuasan Pasien BPJS Rawat Inap di Rumah Sakit Santa Elisabeth Medan. 

Kata Kunci: Mutu Pelayanan, Kepuasan Pasien BPJS, Rawat Inap.
Involutive curable cognitive disorders in elderly people
Authors: Fatenkov OV  , Simerzin VV  , Krasovskaya MA  , Sytdykov IKh
Published: October 2019

The review article describes the characteristics of curable involutive cognitive impairment in the elderly. It is noted that mild cognitive impairment is predominantly neurodynamic in nature, but over time it can transform into a syndrome of moderate cognitive impairment, which, sometimes, is a precursor of dementia. Special attention is given to the clinical manifestations of mild and moderate cognitive impairment, diagnostic criteria, the course of the disease, and its medical and social impact.
Patient-focused medical care techniques in a hospital
Authors: Suslin SA  , Vavilov AV  , Ginnyatulina RI
Published: October 2019

Objectives – to improve the organizational processes in the municipal hospital.
Material and methods. The study was conducted in Samara City Clinical Hospital №1 named after N.I. Pirogov. The methods of organizational modeling and statistical analysis were applied.
Results.The following patient-centered care techniques were introduced in the large multi-facility hospital: special logistics in the hospital admissions unit; models of "comfortable patient admission" and "friendly environment"; integrated information exchange with the emergency medical setting; modern equipment; new landscape; updated security and quality management systems. Routing in the admissions unit is organized according to a "3H" triage system – patients with different severity of conditions are sorted to "red', "yellow" and "green" zones. The "red" zone is intended for patients in extremely serious condition, with impaired vital functions. The "yellow" zone receives patients who are in a serious condition or in a state of moderate severity, with a violation of independent movement. The "green" zone accumulates patients whose health condition is not life threatening. The hospital's quality management system complies with the international standard ISO 9001:2015.
Conclusion. Implemented patient-focused care techniques set the best level of quality, costs and time of medical care thus ensuring the persistent development of the institution. The international quality management standards contribute to the wide dissemination of new principles of hospital management – focus on the patient, on the quality of care.
EXTERNAL LABOUR MIGRATION IN UKRAINE: MOTIVES, SCOPE, CONSEQUENCES
Authors: Sarioglo Volodymyr
Published: October 2019

The article is devoted to the study of age and gender, professional and qualification characteristics of labour migrants from Ukraine. It is shown that gender, age, qualification and work experience in Ukraine can be important factors in labour migration, in particular, to determine its motives. They can also essentially determine the effects of labour migration processes, primarily on national and regional labour markets. The main sources of data for studying the processes of external labour migration in Ukraine are considered. On the example of Lviv and Zakarpattya regions, main directions of the use of labour migrants' incomes have been analysed.
PARADIGMS OF DE-DOLLARIZATION, CHALLENGES AND ANALYSIS OF EXPECTED RESULTS IN GEORGIA
Authors: Abuselidze George , Surmanidze Mzia
Published: October 2019

In terms of the efficiency of monetary policy and economic stability, de-dollarization and its analysis, its impact on the economy are the topical issues. The purpose of this paper is to describe the dollarization and de-dollarization process, which reflects in the economic and economic processes. It also reflects the problems that impede the growth of de-dollarization and the events that make a positive effect on it.
The purpose of the work is to determine the place and role of de-dollarization and to identify ways to improve its regulation. This work refers to the study of foreign experience and its prospects in Georgia.
REGULATION OF DEVELOPMENT OF INVESTMENT AND BUILDING ACTIVITIES IN UKRAINE: ORGANIZATIONAL AND LEGAL ASPECTS
Authors: Mykhailo Sadoviak
Published: October 2019

Introduction. It is ascertained that the construction sector has a social orientation. It is an investment- capacious sector of the national economy. It is noted that the general trend of recent years is to reduce the volume of construction work performed, reduce construction activity, worsen the financial condition of construction companies and reduce their number. It is substantiated that the main factor that determines such a state of affairs in housing construction and defines the negative growth rates of housing volumes is the slowdown in investment activity. Therefore, the investment process is one of the most important directions of development of state regulation and management.
Purpose. Organizational and legal methods of state regulation have a direct impact on the subjects of investment activity. Therefore, the purpose of the article is to consider organizational and legal methods of state regulation of investment processes in the context of the transformational development of the residential sector.
Method (methodology). To achieve the goal of the article the following research methods have been used: method of generalization, method of comparison, historical method.
Results. It is noted that the development of the regulatory framework in Ukraine is carried out taking into account the experience and requirements of the European Union. However, achievements in this area are insignificant and require further improvement to improve the investment climate in the country. An important step in increasing the investment attractiveness of the construction industry is the harmonization of the system of technical regulation of Ukraine with international standards.
It is concluded that separately applied administrative regulators cannot always effectively influence the maintenance of the orderliness of the components of the innovation and investment process in the field of housing construction. Objectively, such state regulation is needed, in which a complex of motivation regulators will be applied. Joint actions of state regulators and market self-regulators will contribute to achieving the optimal structure and infrastructure of investment and construction activities of business entities.
MODEL OF BALANCED INNOVATIVE MANAGEMENT BY IRON ORE ENTERPRISES PRODUCTION
Authors: Vorobiov Ruslan
Published: October 2019

The article is based on the idea of developing a mathematical economic model of balanced innovative management of the production of iron ore enterprises. It has been determined that in the era of global and local economic crises, the non-specialized entities of entrepreneurial activity, which in their natural state are iron ore enterprises, have become especially vulnerable. Monopoly, on the one hand, is a positive phenomenon that allows increasing the concentration of efforts and resources in order to achieve the greatest efficiency and profitability. On the other hand, it is a factor of significant losses under certain circumstances. That is, in the case of an unfavourable state of the domestic and / or foreign markets, significant reductions (in some cases to practically zero) of sales volumes, with subsequent decrease of production output and other negative events that may occur thereafter can be substantially reduced. Consequently, such entities (and in the first place iron ore enterprises), first of all, need modern tools of balanced innovation management of their own production.
It is proved that the most optimal basis for the formation of such an instrument is V. Leontiev's management-model "cost-issue", which is the classical method of systematically quantitatively reflection of any economic relations between different branches of the economic system and, accordingly, can be successfully used for micro level.
Based on the basis of the results of the research, the concept of an adapted economic model of balanced innovation management for the production of an iron ore plant has been constructed.
On the basis of this, a special innovation model for managing the production processes of the iron ore industry has been formed, taking into account the territorial orientation towards the target market and the ratio of basic production resources.
CLUSTER ANALYSIS OF ACTIVITY OF TOURISM ACTIVITY SUBJECTS: REGIONAL ASPECTS
Authors: Dutka Anna , Savitska Olga , Savitska Natalya
Published: October 2019

Introduction. The use of a cluster model is of great importance for the development of tourism. It is precisely the cluster education that effectively provides the opportunity for economic development of the region and the country as a whole. It also increases the competitiveness of the final product, the production activity of enterprises that are a part of clusters in the market. The number of operating clusters in Ukraine remains insignificant despite the implementation of measures, which aim to increase the competitiveness of certain sectors of the economy of Ukraine and its regions on the basis of a cluster model. This is especially true of the tourist industry, which is promising in this regard. Therefore, the study of the possibilities and experience of introducing a cluster model is relevant.
Purpose. The article aims to group regions of Ukraine according to the indicators of activity of legal entities and individuals of entrepreneurs; subjects of tourist activity with the help of cluster analysis, which will enable to identify attractive regions and will allow to develop optimal measures for tourism development for a certain region, taking into account its features.
Method (methodology). In the article, the following general scientific methods have been used: method of analysis, method of synthesis, method of comparison, induction and deduction method, as well as the method of statistical analysis - cluster analysis.
Results. The article substantiates the expediency of forming clusters in the field of tourism business. The essence of the definition of "tourist cluster" has been revealed. The advantages of the operation of tourist enterprises in the cluster have been presented. A system of indicators has been formed. It characterizes the level of development of subjects of tourist activity in the region. According to the results of cluster analysis, four groups of regions of Ukraine have been distinguished according to the indicators of activity of legal entities - subjects of tourist activity and five groups - according to indicators of activity of individuals-entrepreneurs - subjects of tourist activity in 2017.
FEATURES OF MANAGEMENT DECISIONS, THEIR ASSESSMENT AND ESTIMATION IN THE CONDITIONS OF CRISIS
Authors: Nechayeva Iryna
Published: October 2019

Introduction. Management decision approach is considered in this research. Traditional view of crisis management focuses the attention on actions in the conditions of crisis, and gives an insignificant place for prerequisites and consequences of a crisis event. Unlike the traditional one, management decision approach allows to calculate efforts and beforehand to prevent the coming crisis and/or to use its opportunities
Research and estimation of elements of a crisis in the organization will allow defining the following things: strong and weak aspects of preparation for crisis; ways of prevention of repetition of a crisis; ways of reduction of consequences of influence of a crisis; ways of improvement of management of a crisis.
Purpose. The article aims to develop the recommendations about an assessment and estimation of results of administrative decisions in the course of crisis management.
Results. In the research, it is proved that crisis situations have to be considered not as threats, but as opportunities, that is, a starting point in development of the organization.
It is revealed that in the conditions of crisis in process of adoption of the administrative decision the main limiting factors are time, information and expenses. It allows to reduce their negative influence and to increase efficiency of administrative decisions an assessment of that occurred, and to estimate that thing, which is made for the solution of a crisis.
It is established that nature of estimation is influenced by three major factors: scale (sphere), situation (restrictions and intensity) and data (reliability).
The effective administrative decision can be carried out on the basis of assessment and estimation of a crisis situation by two elements: crisis situations (pre-crisis situation; situations at the time of crisis; the situation which developed owing to crisis influence; post-crisis situation), and corresponding administrative components (pre-crisis management; management at the time of crisis approach; management of the situation which developed owing to crisis influence; management of a post-crisis situation). The following factors should also be taken into account: structures, systems, processes, and people. They will give the chance to find out how crisis began and how we can influence efficiency of the administrative decision.
GREEN TOURISM AS A PRIORITY OF THE DIVERSIFICATION OF THE TERRITORIAL DEVELOPMENT OF UKRAINE
Authors: Sakun Alina , Hakal Tetiana
Published: October 2019

Ukraine is losing its competitiveness to agri-food due to inefficient use of the agricultural sector's resource potential. One of the ways to increase the efficiency of the national economy is to diversify territorial development, where green tourism is one of the priority areas
The purpose of the article is to explore the problems of green tourism as a factor in the diversification of rural development.
The article determines that the directions of activity within the limits of the exit from the specialized production in the conditions of rural areas are: processing of agricultural products, rural tourism, trade, consumer services, folk crafts and crafts. These activities are essentially related to agricultural production, contribute to the income of the peasants, improve the quality of life in the countryside. The diversification of the rural economy is accompanied by a synergistic effect. Synergetic effect of new types of production and manifests itself in 4 directions - synergy of sales, operational synergism, investment synergism, management synergism.
THEORETICAL ASPECTS OF DETERMINING THE ESSENCE OF A BENCHMARKING CATEGORY
Authors: Negodenko V. , Vargatiuk M. , Shcherbata M.
Published: October 2019

The constant variability of the external environment complicates the process of conducting economic activity by business entities. This requires the application of new methods of business management to ensure its sustainable development and to create competitive products. Management should pay particular attention to those management concepts that have demonstrated their effectiveness and potential. Among these methods, benchmarking should be singled out as one of the universal ways of increasing the level of competitiveness of enterprises of different spheres of management.
The purpose of the article is to summarize scientific approaches to the concept of benchmarking as an economic category and to determine the author's position on its essence.
The article presents the scientific concepts of defining the essence of benchmarking as an economic category, revealed that there are a considerable number of concepts for consideration of this definition, establishes the universal nature of this concept, since benchmarking is already used in the work of not only enterprises, but also in the organization of management of individual spheres. , territories, etc. The article proposes to use two approaches to considering the essence of benchmarking: static and dynamic, which makes it possible to define this category on the one hand, as a method of management, and, on the other, as determined by external and internal conditions, a constant and variable process. As a result of the research, it is proposed to consider benchmarking as a management method, the essence of which is to distinguish the best experience of economic agents, especially business entities, and to use it in the work of other enterprises, institutions and organizations.
Trends of structural changes in dissemination of advertising
Authors: Voronenko Iryna , Skrypnyk Andrii , Namiasenko Yurii
Published: October 2019

The article points out that a well-functioning information space serves as a basis for boosting economic development and for building a civil society. It is emphasized that despite constant changes in the structure of information space, advertising has been and will be its important component or even driving force. The paper highlights how researchers discuss this issue, and concludes that there are a lot of aspects which have not been considered yet, and need to be studied in detail. It is claimed that one of such aspects is dynamics of structural changes in dissemination of advertising.For the purpose of the study, methods of statistical and econometric analysis, synthesis, generalization and comparison are used.The paper provides an analysis of the global advertising business and calculates percent- ages of advertising expenditures by categories in 2004, 2016 and 2018. Based on the results achieved, it is concluded that the share of advertising expenditures in the global GDP has decreased. It is also stressed that the rivalry between television commercials and Internet advertisements will be more intensive.The impact of the country’s GDP on advertising expenditures is assessed, and it is found that, if per capita GDP grows by $1,000, advertising expenditures will increase by $11 with $5.3 on Internet and $2.3 on television advertisements.The significant growth of Internet users in the world and per 100 of inhabitants in 2001-2017 is driven primarily by young people aged 15-24.Advertising expenditures have doubled in social networks recently. The paper provides an analysis of advertising expenditures by world regions, and percentages of advertising expenditures in Ukraine by categories in 2004 and 2016.It is concluded that advertising expenditures represent just a marginal share in Ukraine’s GDP (0.33 per cent), only half as much as in the world and seven times less than in the developed countries.
PROFIL KROMATOGRAFI LAPIS TIPIS MINYAK ATSIRI SEREH (Cymbopogon citratus)
Authors: Prabandari Rani
Published: October 2019

Abstract.

Rhodinol has been isolated from citronella oil. Isolation of lemongrass oil is done by using the distillation method. Samples used were citronella harvested for 6 months and 9 months. Silent phase used TLC plate slika gel F254 with a size of 2 x 10 cm and the mobile phase used was Toluen: Ethyl Acetate (93: 7). Results of Thin Layer Chromatography HRF profile obtained for experiment I (citronella harvesting age 6 months) 32, 77, 87 and Experiment II (lemongrass harvest age 9 months) respectively 25, 73, 81.
Miguel Hernández y la razón poética
Authors: Berrocal Alfonso
Published: October 2019

El presente artículo explora la relación de amistad entre el poeta Miguel Hernández y la filósofa María Zambrano a partir del poema que Hernández le dedicó a la pensadora y del artículo que ésta escribió sobre él. La relación entre ambos se aborda desde la óptica de presentar elementos poéticos determinantes en la configuración del pensamiento de María Zambrano. Todo ello con la finalidad de identificar como fuentes de la llamada «razón poética» la poesía española de las primeras décadas del siglo xx.
Miguel Hernández para niños
Authors: Sotomayor Sáez María Victoria
Published: October 2019

Desde los años treinta del siglo xx se desarrolla un nuevo concepto de la relación del niño con la poesía, concepto que recibe un nuevo impulso a partir de los setenta, ya que en esta época la literatura infantil en su conjunto experimenta un importante crecimiento. Esto favorece la publicación de poemas y antologías para la lectura infantil, la revalorización del folclore y la creación poética dirigida a este público. Una de las líneas de publicación más destacada son las ediciones y antologías de poetas de nuestra tradición literaria que, aunque no destinaron a los niños sus creaciones, pueden ser leídos y disfrutados por ellos en gran parte de su obra. Miguel Hernández se encuentra entre los poetas más editados, con publicaciones de distinto contenido y forma según la edad de los lectores a los que se dirigen.
THE SITUATION OF URINARY IODINE CONCENTRATION (UIC) AMONG SCHOOL AGE CHILDREN, WOMEN AT REPRODUCTIVE AGE AND PREGNANT WOMEN IN INDONESIA: THE ANALYSIS OF RISKESDAS 2013
Authors: Kartono Djoko , Atmarita Atmarita , Jahari Abas B , Soekirman Soekirman , Izwardy Doddy
Published: October 2019

Iodine Deficiency Disorders (IDD) are the leading cause of goiter, cretinism, developmental delays and other health problems. Iodine deficiency is an important public health issue as it is a preventable cause of intellectual disability. While elimination of iodine deficiency is imperative, it should be noted that excessive intake of iodine can also lead to adverse health effects. This paper analyzed the iodine status using median urinary iodine concentration (MUIC) of school age children (SAC), women of reproductive age (WRA), and pregnant women (PW) who live in the same household from Riskesdas 2013. The total number of households included in the analysis was 13,811 households, from which 6,149 SAC (aged 6 – 12 years), 13,218 WRA (aged 15-49 years), and 578 PW (aged 15-49 years) were enumerated. The national MUIC of SAC, WRA and PWwas  in the normal range indicated that  the iodine status was adequate using WHO epidemiological criteria. Iodine status in some sub-populations indicated deficiency, however, in terms of geographic characteristics people who live in the urban has better iodine status compared to rural areas. Similarly, populations in richer economic quintiles had better iodine status. Only pregnant women in the 1st and 2nd quintile were deficient. Almost all regions in Indonesia showed the MUIC was in the normal adequate range, except NTT-NTB, Maluku-Papua, and East Java for pregnant women who tend to have lower MUIC (<150 µg/L). The status of iodized salt at the household was detected using both Rapid Test Kit/RTK as well as Titration. The result demonstrated a strong association between salt iodine level and iodine status. The MUIC for all three groups were lower when the iodine level in salt was lower, then increased when the levels of iodine content in salt increased. The iodine status of pregnant women consuming non-iodized salt was inadequate. The detrimental effect of iodine deficiency on the mental and physical development of children as well as on the women of reproductive age has been recognized. Indonesia still needs the salt iodization program to keep the iodine status in the normal range. In particular coverage with adequately iodized salt needs to be improved in order to improve the iodine status of pregnant women. For the prevention of Iodine disorders (insufficient), monitoring should be undertaken in regular basis to assess the MUIC, especially for pregnant women.
THE EFFECTS OF ROOM SERVICE TO IMPROVE PATIENTS’ FOOD SATISFACTION AND FOOD ACCEPTANCE
Authors: Iqbal Muhammad , Susetyowati Susetyowati , Purba Martalena Br
Published: October 2019

The improvement of patients’ food satisfaction and acceptance in the hospitals is primarily needed in the food service  system.  Room service is a new concept in the food service area. This study aims to compare the effects of two different types of food service systems; room service and conventional service system. The study with quasi-experimental design is conducted to the subject of 66 inpatients who were taken using a quota sampling method. Subjects were divided into different groups, the treatment groups (room service) and control groups (conventional). Leftover food between groups was compared for 9 large meals to determine acceptability. Food satisfaction is measured on the last day with using questionnaire. The study was conducted in April-June 2014. Chi-Square test and logistic regression were used for analysis of research data. There were significant differences food satisfaction (RR=4.6; p=0.0001) and food acceptance (RR=1.94; p=0.0488) between control and treatment group. The logistic regression test showed that room service group had higher food satisfaction and food acceptance level than control group after controlling confounding factors, which were 12,11 times (95% CI 3,593 – 37,219) and 2,38 times (95% CI 0,68-8,31), respectively. The room service increases food satisfaction and food acceptance of patients compared with conventional systems.
LENGTH OF PATERNAL EDUCATION IS ASSOCIATED WITH HEIGHT-FOR-AGE OF SCHOOL CHILDREN IN RURAL AREA OF SEPATAN TIMUR-TANGERANG
Authors: Angkasa Dudung , Sitoayu Laras , Jus'at Idrus
Published: October 2019

Paternal educational status plays an important role in long-term nutritional status of children. The objective of this study was to investigate the association between paternal factors and school children nutritional status in rural setting, Indonesia. A cross-sectional study carried out in September  up to November 2015 involving 368 primary public school children in Sepatan Timur, Tangerang. Structured questionnaires were administered to parents, containing household characteristics such as length of school year, working status, number of siblings. Children weight and height were measured using a weighing scale and microtoise, respectively. Anthropometric indices, height-for-age (HAZ) and body mass index for-age (BAZ), were produced by using WHO-Antroplus. Children’s food intake and snacking habits were assessed using single 24 hours food recall and food frequency questionnaire, respectively. Others variables were physical activity and infectious disease history. Multiple regression analyses were employed to enquire research questions. Results indicated that children with father’s educational status less than 9 years had a significant 0.607 lower HAZ if compared to those educational status more or equal to 9 years after adjustment for mother’s schooling year, working status, number of household member, children’s history of diarrhea and physical activity status, sex, age and snacking frequency. Conclusion, father’s educational status was associated with height for age among school children in rural area of Sepatan Timur. ABSTRAK Pendidikan orang tua berperan penting dalam menentukan status gizi anak dalam jangka panjang. Penelitian bertujuan menganalisis hubungan faktor orang tua dengan status gizi anak sekolah di wilayah pedesaan. Penelitian menggunakan desain potong lintang dilaksanakan selama September-November 2015 dengan melibatkan 368 anak sekolah dasar negeri di Sepatan Timur, Tangerang. Kuesioner terstruktur diberikan pada orang tua untuk mengetahui lama sekolah, status pekerjaan, dan jumlah anak. Berat dan tinggi badan akan diukur dengan timbangan badan dan microtoise kemudian dihitung indeks antropometri tinggi badan menurut umur (TB/U) dan indeks massa tubuh menurut umur (IMT/U). Konsumsi sampel dinilai dengan food recall 24 jam satu hari dan kuesioner frekuensi makanan. Variabel lain yang diamati ialah aktivitas fisik dan riwayat infeksi. Analisis Regresi berganda digunakan untuk menjawab tujuan. Hasil menunjukkan bahwa sampel dari ayah yang berpendidikan <9 tahun lebih rendah skor TB/U sebesar 0,607 poin dibandingkan sampel dari ayah yang berpendidikan >9 tahun setelah dikontrol lama pendidikan ibu, status pekerjaan, jumlah anak, riwayat diare, aktivitas fisik, jenis kelamin, umur dan frekuensi jajan anak. Penelitian ini menyimpulkan bahwa pendidikan ayah yang rendah berhubungan dengan tinggi badan anak pada anak sekolah di wilayah pedesaan, Sepatan Timur. Kata kunci: pendidikan ayah, status gizi, anak sekolah, pedesaan
DISTRIBUSI DAN FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KADAR HEMOGLOBIN A1C (HbA1c) PADA SUBJEK DEWASA INDONESIA
Authors: Irmayanti Irmayanti , Farmawati Arta , Purba Martalena Br
Published: October 2019

HbA1c is a parameter that may be used in predicting and diagnosing diabetes. Since diabetes is predicted to increase in Indonesia, it is necessary to understand the distribution and associated factors of HbA1c in the general Indonesian population. However, those data are still limited. This study aims to determine the distribution of HbA1c and its associated factors in Indonesian adults. We conducted a cross-sectional study analyzing data from Indonesia Family Life Survey (IFLS) 2014-2015. HbA1c was analyzed using dried blood spot (DBS) specimen with Bio-Rad D10 HPLC. We performed Student’s t test and ANOVA to show the results of the bivariate analyses and multiple linear regression to determine the association between variables. The study included 4.101 subjects (20-59 years) without diabetes and provided an overview of the distribution of HbA1c levels based on socio-demographic factors and smoking behavior described in percentiles. The mean of HbA1c was 5.35% with a standard error of 0.01. The threshold value of HbA1c for prediabetes (5.7%) corresponded approximately to the 75th percentile. Although there were differences in HbA1c distribution, socio-demographic factors such as education levels, employment, and settlement region as well as smoking were not independently associated with HbA1c levels in Indonesian adults. Furthermore, age and sex were associated with HbA1c.
QUANTITY AND QUALITY OF BREAKFAST OF CHILDREN AGED 2.0 TO 12.9 YEARS IN INDONESIA
Authors: Harahap Heryudarini , Widodo Yekti , Sandjaja Sandjaja , Khouw Ilse , Deurenberg Paul
Published: October 2019

Doing breakfast among children is a public health concern as seen at one of the messages in ‘Indonesian balanced nutrition which state ‘breakfast every day’. The aim of this analysis is to determine the quantity and quality of Indonesian children’s breakfast based on children and parent characteristics, as well as nutritional status. Subjects were 2629 children, aged 2.0–12.9 years, included in the Southeast Asian Nutrition Study. The amount of the breakfast is categorized as very inadequate if <15 percent; inadequate if 15 to < 25 percent; or adequate if ≥ 25 percent of the Indonesian RDA. The quality of breakfast was categorized as ‘not good’, if the breakfast skips one or more components of energy, protein and/or vitamins/minerals, or ‘good’ if the breakfast provides energy, protein and vitamins/minerals. The results indicated that on average only 31.6 percent of the children were categorized as having adequate breakfast consumption and 21.6 percent having good quality breakfast. Only 9.2 percent of children have adequate and good quality breakfast. Adequacy of breakfast differed between children, parent characteristics, and nutritional status, but only age has an association with the quality of breakfast (p<0.05). The nutrition education about good breakfast should be included as the part of curriculum, and school canteens provided a good food, as well as a campaign about Indonesian balanced nutrition slogan number 1 ‘have breakfast every day’ should be socialized.
Evaluation of risk factors predicting surgical treatment in tuboovarian abscess cases
Authors: Çoşkun Bora , Şimşir Coşkun
Published: October 2019

Objective:  The main outcome measure of the present study was to find out the predictive factors affecting the need for surgery in patients diagnosed with tuboovarian abscess (TOA). We also examined the success of different medical treatment regimens in those patients.

Material and Methods: This was a retrospective clinical study performed on 96 TOA patients who were treated in the current hospital between August 2015 and August 2019. All patients underwent physical examination and ultrasonographic imaging with some laboratory tests to investigate the presence of TOA. Two different medical treatment regimens were administered as recommended by the international guidelines after the initial diagnoses. Patients with worsening clinical and/or laboratory findings and/or who did not respond to medical treatment were taken to surgery. Predictive factors for surgical intervention and success rates of medical treatment regimens were evaluated.

Results: White blood cell (WBC) levels≥ 16000 and abscess size≥ 7 cm was strongly correlated with the requirement for surgery. The 94 patients received the Regimen 1. Six patients underwent surgery urgently when they were under medical treatment. Regimen 1 failed in 21 (22.34 %) patients out of 94, Regimen 2 was shifted to.  Six patients (28.5%) out of 21 underwent surgery because of treatment failure with Regimen 2. Recovery was achieved in the remaining 15 (71.4%) patients.

Conclusion: The success of medical TOA treatment was found to be high. Therefore, medical treatment can be applied first, except in case of acute abdomen. It was found that WBC and abscess diameter in patients with TOA in admission were the most important factors affecting the need for surgery. The factors affecting the duration of medical treatment were found to be age, WBC count, CRP (C-Reactive Protein), ESR (Erythrocyte Sedimentation Rate) and NLR (Neutrophil/Lymphocyte Ratio) levels.
The use of methotrexate, vincristine, L-asparaginase and dexamethasone for salvaging adult acute lymphoblastic leukemia and lymphoma: a real-life experience
Authors: Tanrikulu Funda Pepedil , Buyukkurt Nurhilal , Yeral Mahmut , Aytan Pelin , Solmaz Soner , Korur Asli , Gereklioglu Cigdem , Kozanoglu İlknur , Boga Can , Ozdogu Hakan
Published: October 2019

Despite recent improvements in the treatment options, adult relapsed/refractory Acute Lymphoblastic Leukaemia (ALL) and lymphoblastic lymphoma (LBL) exhibit poorer cure rates than in childhood. Since, the mainstay difference of childhood multidrug regimens is L-Asparaginase, we sought to salvage adult patients with a protocol containing methotrexate, vincristine, conventional L-asparaginase, and dexamethasone (MOAD). In this study, we aimed to summarize our experience.

Methods: Adult patients with relapsed/refractory ALL and LBL followed-up in our institution between 2017 and 2018 were reviewed and those treated with MOAD protocol were retrospectively included in the study. Clinical data, treatment responses, and adverse events were summarised. The protocol featured 28-day cycles of methotrexate 200 mg/m2 intravenously (IV) on days 1 and 15; vincristine 1.4 mg/m2 IV on days 1, 8, and 15; L-asparaginase 10,000 IU/m2 IV twice weekly; and dexamethasone 40 mg IV or orally on days 1–4 and 15–18.

Results: A total of eight patients were enrolled, of median age 37 years (range: 21–58 years). Four patients were recovered after transplantation. Complete remission was evident in 38%. Two such patients underwent allogeneic hematopoietic stem cell transplantation after the protocol. Another patient with lymphomatous disease achieved partial remission and underwent successful transplantation. L-asparaginase did not trigger any clinically evident hypersensitivity reaction; the most common adverse events associated with the protocol were hypofibrinogenemia, anemia, and febrile neutropenia.

Conclusions: The MOAD protocol was effective and tolerable, enabling to salvage before and after transplantation, particularly in patients with relapsed/refractory T-cell acute lymphoblastic leukemia and lymphoblastic lymphoma.
VULVAR TUMOR - CASE REPORT AND LITERATURE REVIEW
Authors: JB Zimmermmann , BCF de Morais , AJF de Paula , ALM Costa , BA Dias , AFS Salles e Silva , BR Bonfim , BT Resende , ACV Ferreira , MC Marangoni , AR Paiva , LMA da Fonseca , MSF Novais
Published: October 2019

The vulvar region is a complex area because it comprises many elements, besides the skin itself. Therefore, it can present a variety of relatively rare tumors that can be classified based on source tissue (epithelial or mesenchymal). Benign epithelial tumors in the connective tissue are not often diagnosed in the vulvar area, which is mostly affected by fibroepithelial polyps.
Mini review on Protein – Protein and DNA/RNA – protein interactions in biology
Authors: E Beeram
Published: October 2019

RNase H1 generally processes the RNA- DNA hybrids through non specific interaction between HBD and the ds RNA/DNA hybrid. There are no direct protein- protein interactions between the hybrid and HBD of RNase H1. The DNA binding region is highly conserved compared to RNA binding region and the Kd for RNA/DNA hybrid is less compared to ds RNA than to that of ds DNA [1]. HBD increases the processivity of RNase H1 and mutations in RNA binding region is tolerated compared to DBR. The RNA interacts between ɑ2 and β3 region with in the loop and with the protein in shallower minor groove.
Microwave-assisted Synthesis of 2-Substituted 4,5,6,7-Tetrahydro-1,3-thiazepines from 4-Aminobutanol
Authors: Mollo María C , Kilimciler Natalia B , Bisceglia Juan A , Orelli Liliana R
Published: October 2019

A general procedure for the synthesis of 2-substituted tetrahydro-1,3-thiazepines is presented, by MW-assisted cyclization of 4-thioamidobutanols. The acyclic precursors were prepared in high overall yields by an expeditious three step diacylation/thionation/deprotection sequence from 4-aminobutanol. Microwave assisted ring closure of 4-thioamidoalcohols promoted by trimethylsilyl polyphosphate (PPSE) in solvent-free conditions allowed for the synthesis of several hitherto unreported seven-membered iminothioethers bearing 2-aryl, alkenyl, aralkyl and alkyl substituents. The cyclodehydration reaction is likely to involve a SN2-type displacement and affords good to excellent yields of the desired heterocycles in very short reaction times.
FRACTIONAL INTEGRO-DIFFERENTIAL EQUATIONS WITH NONLOCAL CONDITIONS AND Ψ–HILFER FRACTIONAL DERIVATIVE
Authors: Abdo Mohammed S. , Panchal Satish K. , Hussien Hussien Shafei
Published: October 2019

Considering a fractional integro-differential equation with nonlocal conditions involving a general form of Hilfer fractional derivative with respect to another function. We show that weighted Cauchy-type problem is equivalent to a Volterra integral equation, we also prove the existence, uniqueness of solutions and Ulam-Hyers stability of this problem by employing a variety of tools of fractional calculus including Banach fixed point theorem and Krasnoselskii's fixed point theorem. An example is provided to illustrate our main results.
NON-SYMMETRIC FLOW OVER A STRETCHING/SHRINKING SURFACE WITH MASS TRANSFER
Authors: Lok Yian Yian , Merkin John H. , Pop Ioan
Published: October 2019

The non-symmetric flow over a stretching/shrinking surface in an other-wise quiescent fluid is considered under the assumption that the surface can stretch orshrink in one direction and stretch in a direction perpendicular to this. The problem is reduced to similarity form, being described by two dimensionless parameters, γ the relative stretching/shrinking rate and S characterizing the fluid transfer throughthe boundary. Numerical solutions are obtained for representative values of γ and S, a feature of which are the existence of critical values γc of γ dependent on S, these being determined numerically. Asymptotic forms for large γ and S, for both fluid withdrawal, S > 0 and injection S < 0 are obtained and compared with the corresponding numerical results.