bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental Dengue 4 Infection Increases the Production of NS1 Protein and Expression of MicroRNAs-15/16 Levels, Triggering an Apoptosis Caspase Induced Pathway
Authors: Casseb Samir Mansour Moraes , Melo Karla Fabiane Lopes de , Carvalho Carlos Alberto Marques de , Santos Carolina Ramos dos , Franco Edna Cristina dos Santos , Vasconcelos Pedro Fernando da Costa
Published: December 2022

The World Health Organization has estimated an annual occurrence of approximately 392 million dengue virus (DENV) infections in more than 100 countries where the virus is endemic, and this represents a serious threat to humanity. DENV is a serologic group with four distinct serotypes (DENV1, DENV2, DENV3, and DENV4) belonging to the genus Flavivirus, family Flaviviridae. Dengue is the most widespread mosquito-borne disease in the world. The ~10.7 kb DENV genome encodes three structural proteins (capsid [C], pre-membrane [prM], and envelope [E]) and seven non-structural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5). The NS1 protein is found both as a membrane-associated dimer and as a secreted, lipid-associated hexamer. Dimeric NS1 is found on membranes both in cellular compartments and on the cell surface. Secreted NS1 (sNS1) is often present in patient serum at very high levels, which correlates with severe dengue symptoms. This study was carried out to find out how the NS1 protein, miRNAs 15 and 16, and apoptosis are related to each other during DENV4 infection in human liver cell line culture. The Huh 7.5 and HepG2 strains were infected with DENV4, and after different times of infection, miRNA-15 and miRNA-16, viral load, NS1 protein, and caspases 3 and 7 were quantified. This study demonstrated that miRNAs 15 and 16 are overexpressed during infection of HepG2 and HuH7.5 cells by DENV4 and have a relationship with NS1 protein expression, VDEN4 viral load, and caspase pathways 3 and 7, thus making these miRNAs interesting targets for markers of injuries during VDEN infection in human hepatocyte cells.
Unravelling Effects of Anti-aging Drugs on C. elegans using Liposomes
Authors: Zhang Aihan , Hsiung Kuei Ching , Kern Carina , Wang Yuting , Girtle Anna , Xu Nuo , Gems David
Published: December 2022

Liposome-mediated delivery is a possible means to overcome several shortcomings with C. elegans as a model for identifying and testing drugs that retard aging. These include interactions between drugs and the nematodes’ bacterial food source, and failure of drugs to be taken up into nematode tissues. To explore this, we have tested liposome-mediated delivery of a range of fluorescent dyes and drugs in C. elegans. Liposome encapsulation led to enhanced effects on lifespan, using smaller quantities of compound, and enhanced uptake of three dyes into the gut lumen. However, one dye (Texas red) did not cross into nematode tissues, indicating that liposomes cannot ensure uptake of any compound. Of six compounds previously reported to extend lifespan (vitamin C, N-acetylcysteine, glutathione (GSH), trimethadione, thioflavin T (ThT) and rapamycin), this effect was reproduced for the latter four in a condition-dependent manner. For GSH and ThT, antibiotics abrogated life extension, implying a bacterially-mediated effect. With GSH, this was attributable to reduced early death from pharyngeal infection, and associated with alterations of mitochondrial morphology in a manner suggesting a possible innate immune training effect. By contrast, ThT exhibited antibiotic effects. For rapamycin, significant increases in lifespan were only seen when bacterial proliferation was prevented. These results document the utility and limitations of liposome-mediated drug delivery for C. elegans. They also show how nematode-bacteria interactions can determine the effects of compounds on C. elegans的壽命有多種方式。
Preparation, Characterization, DFT Calculations, Antibacterial and Molecular Docking Study of Co(II), Cu(II), and Zn(II) Mixed Ligand Complexes
Authors: Al-Fakeh Maged S. , Messaoudi Sabri , Alresheedi Faisal , Albadri Abuzar , El-Sayed Wael A , Saleh Emran
Published: December 2022

[Co(AMPY)(DAPY)Cl2(H2O)].H2O (1) [Cu(AMPY)(DAPY)Cl2(H2O)].H2O (2) [Zn(AMPY)(DAPY)Cl2(H2O)] (3) were prepared from the ligands; AMPY = 2-amino-4-methylpyrimidine (L1), DAPY = 2,3-diaminopyridine (L2) and CoCl2.6H2O, CuCl2.2H2O and ZnCl2 in water/ethanol solutions and the three products characterized by elemental analysis, ultraviolet-visible spectroscopy (UV–Vis), Fourier-transform infrared spectroscopy (FT-IR), magnetic susceptibility, molar conductivity methods, and TGA analysis. The X-ray powder diffraction of the Co(II), Cu(II), and Zn(II) compounds showed that the geometry of monoclinic and SEM analysis revealed their morphology with a smooth surface. Molecular modeling was performed for all compounds using the density functional method DFT/B3LYP to study the structures and the frontier molecular orbitals (HOMO and LUMO). We have used Gaussian09 software for the calculations. In this study, different complexes were tested against Gram negative and Gram positive bacterial species to give insight into their broad-spectrum effects. The used pathogenic strains were two Gram positive species "Staphylococcus aureus and Micrococcus luteus" and two Gram negative species "Salmonella thyphimurium and Escherichia coli. The antifungal activity was evaluated against a pathogenic reference strain of the yeast Candida albicans. The antimicrobial and antioxidant assay results demonstrate that the tested compounds are effective against Gram positive and negative bacteria. Additionally, the compounds have an antifungal effect against Candida albicans with a maximum inhibitory zone of 2.5cm. The results demonstrated high antioxidant potential for the Zn(II) complex with a DPPH scavenging of 91.5%, however, the Cu(II) complex was low (16.5%). The data of docking with tyrosyl-tRNA synthetase presented that all compounds fit very well in the catalytic pockets of the proteins of the receptor.
Aspek Hukum Tanah Tongkonan sebagai Harta Pusaka yang Tidak Terbagi
Authors: Alfredy Alfredy , Nur Sri Susyanti , Arisaputra Muhammad Ilham
Published: December 2022

Penelitian ini bertujuan untuk mengetahui aspek hukum tanah tongkonan sebagai harta pusaka yang tidak terbagi. Penelitian ini menggunakan jenis penelitian hukum empiris yaitu penelitian tentang bekerjanya hukum (law in action) di masyarakat. Penelitian dilakukan di Tongkonan Remen, Kelurahan Laang Tanduk, Kecamatan Rantepao, Kabupaten Toraja Utara, Sulawesi Selatan. Data penelitian dianalisis secara deskriktif kualitatif. Hasil penelitian menunjukkan bahwa status tanah tongkonan yang berada dalam wilayah adat tongkonan adalah tanah komunal yang ditandai dengan adanya rumah tongkonan layuk sebagai simbol marga (keluhuran) suku Toraja. Keluhuran tersebut juga menjadi nilai yang merekatkan seluruh anggota keluarga dan representasi lembaga yang mengatur kehidupan masyarakat Toraja. Dalam sistem pengelolaan aset berupa tanah tongkonan dan wilayah adat tongkonan ditandai dengan adanya peranan dan fungsi lembaga adat sebagai pengelola dalam hal pemanfaatan tanah komunal dan pemeliharaan harta pusaka tongkonan secara berkala. Pengelolaan tanah Tongkonan dilakukan oleh keturunan yang bermukim di lokasi tanah tersebut. Setiap keturunan dari pemilik tanah Tongkonan berhak untuk tinggal dan membangun di atas tanah Tongkonan dengan syarat sepanjang mereka ikut berpartisipasi memelihara dan menjaga tanah milik keluarga tersebut. Artinya, segala bentuk keputusan lahir dari dalam tongkonan tersebut melalui musywarah rumpun sebuah tongkonan.
Real-Time Suture Thread Detection with an Image Classifier
Authors: Horio Kyotaro , Harada Kanako , Muto Jun , Nakatomi Hirofumi , Saito Nobuhito , Morita Akio , Watanabe Eiju , Mitsuishi Mamoru ,   The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan,   Fujita Health University Hospital 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan,   The University of Tokyo Hospital 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan,   Nippon Medical School 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan,   Jichi Medical School Hospital 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan
Published: December 2022

Micro-anastomosis is considered to be a difficult task even for skilled surgeons. Our group has developed a surgical robotic system to assist surgeons. Going further, the detection of surgically relevant objects in the microscopic view is indispensable for the automation or semi-automation of the system. This paper proposes a novel surgical thread detector inspired by an automatic crack detection method. The proposed method achieved a Dice score of 76.30% and an intersection over union (IOU) of 66.08% at 34.50 fps.
Basic Experiments Toward Mixed Reality Dynamic Navigation for Laparoscopic Surgery
Authors: Chen Xiaoshuai , Sakai Daisuke , Fukuoka Hiroaki , Shirai Ryosuke , Ebina Koki , Shibuya Sayaka , Sase Kazuya , Tsujita Teppei , Abe Takashige , Oka Kazuhiko , Konno Atsushi ,   Graduate School of Science and Technology, Hirosaki University 3 Bunkyo-cho, Hirosaki, Aomori 036-8561, Japan,   Graduate School of Information Science and Technology, Hokkaido University Kita 14, Nishi 9, Kita-ku, Sapporo, Hokkaido 060-0814, Japan,   Faculty of Engineering, Tohoku Gakuin University 1-13-1 Chuo, Tagajo, Miyagi 980-8511, Japan,   Department of Mechanical Engineering, National Defense Academy of Japan 1-10-20 Hashirimizu, Yokosuka, Kanagawa 239-8686, Japan,   Graduate School of Medicine, Hokkaido University Kita 15, Nishi 7, Kita-ku, Sapporo, Hokkaido 060-8638, Japan
Published: December 2022

Laparoscopic surgery is a minimally invasive procedure that is performed by viewing endoscopic camera images. However, the limited field of view of endoscopic cameras makes laparoscopic surgery difficult. To provide more visual information during laparoscopic surgeries, augmented reality (AR) surgical navigation systems have been developed to visualize the positional relationship between the surgical field and organs based on preoperative medical images of a patient. However, since earlier studies used preoperative medical images, the navigation became inaccurate as the surgery progressed because the organs were displaced and deformed during surgery. To solve this problem, we propose a mixed reality (MR) surgery navigation system in which surgical instruments are tracked by a motion capture (Mocap) system; we also evaluated the contact between the instruments and organs and simulated and visualized the deformation of the organ caused by the contact. This paper describes a method for the numerical calculation of the deformation of a soft body. Then, the basic technology of MR and projection mapping is presented for MR surgical navigation. The accuracy of the simulated and visualized deformations is evaluated through basic experiments using a soft rectangular cuboid object.
Development of Integrated Leader Controller for Forceps/Retractor Manipulation in Single-Port Water-Filled Laparo-Endoscopic Surgery
Authors: Kawamura Kazuya , Shimura Yuma ,   Center for Frontier Medical Engineering, Chiba University 1-33 Yayoi-cho, Inage-ku, Chiba-shi, Chiba 263-8522, Japan,   Graduate School of Science and Engineering, Chiba University 1-33 Yayoi-cho, Inage-ku, Chiba-shi, Chiba 263-8522, Japan
Published: December 2022

Single-port water-filled laparo-endoscopic surgery (WaFLES) is a surgical procedure used for treatment in an environment filled with isotonic water in the abdominal cavity under a single-port condition. In this study, we developed two leader controllers for the forceps manipulator and retractor to generate and maintain a surgical workspace for a single-port WaFLES support robot. The development of the specific controller for each device increased the operation time and complicated the motion, such as regripping. We integrated the two functions as a controller to prevent the problem above. We performed grasping and retracting tasks in the virtual surgical workspace to evaluate the proposed controller. Based on the experimental results, we clarified the effect on the operation time by a different mechanism and observed that arranging the switch decreased the operation time. In addition, one of the proposed leader controllers improved operability in terms of operation time during selection and switching from the retractor to the forceps manipulator. However, the arrangement of the switch could adversely affect controller operability when switching from a simple operation (requiring only position control during retractor operation) to a complex operation (requiring both position and posture control during forceps operation). Furthermore, manipulation errors were observed using either of the proposed controllers. Therefore, the sensing procedure of the controller should be improved by addressing these errors in software and hardware.
Development of Intraoperative Plantar Pressure Measurement System Considering Weight Bearing Axis and Center of Pressure
Authors: Hosoi Izumu , Matsumoto Takumi , Chang Song Ho , An Qi , Sakuma Ichiro , Kobayashi Etsuko ,   Schoool of Engineering, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan,   School of Medicine, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan,   Department of Orthopedic Surgery, JCHO Tokyo Shinjuku Medical Center 5-1 Tsukudo-cho, Shinjuku-ku, Tokyo 162-8543, Japan,   School of Frontier Sciences, The University of Tokyo 5-1-5 Kashiwanoha, Kashiwa-shi, Chiba 277-0882, Tokyo
Published: December 2022

To prevent postoperative complications in corrective surgery for foot deformities such as hallux valgus and pes planus, it is critical to quantitatively predict the postoperative standing-position plantar pressure distribution during the operation. The authors have previously proposed an intraoperative plantar pressure measurement system (IPPM) that allows for the measurement of a supine patient’s plantar pressure distribution that is equivalent to that in the standing position. This system consists of an IPPM device comprising of a force plate and pressure distribution sensor, an optical three-dimensional position measurement device, a navigation monitor, and a PC. The plantar pressure distribution in the standing position is reproduced by navigating the operator, as he or she presses the IPPM device against the patient’s sole so that the weight-bearing axis (floor reaction force vector) and femoral head center are as close to each other as possible. However, in our previous study, the reproducibility of the standing position plantar pressure distribution was insufficient. Therefore, in the present study, we add a navigational function that can be used to bring the centers of pressure in the standing position and under measurement, as well as to correct the IPPM’s self-weight in the measured force. The improved device was used in an experiment with nine healthy subjects, and the similarity of the plantar pressure distribution in the standing and supine positions was evaluated using normalized cross-correlation, yielding an average of 0.90. Furthermore, in an evaluation experiment with ten orthopedic surgeons, it was observed that using the system reproduced the plantar pressure distribution significantly better than when the system was not used. These results indicate that the present system can predict the plantar pressure distribution in the standing position. We believe that this system can contribute to reducing complications after foot surgery.
Development of a Novel Rollator Equipped with a Motor-Driven Chest Support Pad and Investigation of its Effectiveness
Authors: Huang Jian ,   Faculty of Engineering, Kindai University 1 Takaya Umenobe, Higashi-Hiroshima City, Hiroshima 739-2116, Japan, Koyachi Noriho
Published: December 2022

In recent years, a rapid increase in bedridden elderly, due to cerebral strokes and other diseases, has become a social problem due to soaring medical costs and heavy burden of long term care support. Therefore, development of walk rehabilitation devices for the elderly, suffered from cerebral strokes, is strongly expected. In the research so far, the authors have developed a rollator with a chest support pad that can rotate freely with one degree of freedom, and the effectiveness of its walk assistance was evaluated. In this study, a novel rollator using a motor-driven chest support pad was developed. A compact system to combine data collect system and motor control was configured. Walk measurements for six subjects were conducted using the developed rollator. The relationship between the movements of the lower limbs and rotation of the motor driven chest support pad was investigated. Time series and power spectrum results were analyzed, and the effectiveness of the motor-driven chest support pad on movement of the lower limb during walking was discussed.
Adapting Balance Training by Changing the Direction of the Tensile Load on the Lumbar Region
Authors: Miyazaki Tetsuro , Aoki Takuro , Aizawa Junya , Kawase Toshihiro , Sogabe Maina , Kawashima Kenji ,   Department of Information Physics and Computing, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan,   Faculty of Health Science, Juntendo University 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan,   Department of Information and Communication Engineering, School of Engineering, Tokyo Denki University 5 Senju Asahi-cho, Adachi-ku, Tokyo 120-8551, Japan
Published: December 2022

In this study, we investigated trainees’ adaptation by conducting static balance training in a tandem standing posture. The horizontal tensile force loads in the front, back, left, and right directions were applied using pneumatic artificial muscles. We analyzed the adaptation that occurred during training by changing the direction of the horizontal tensile load on the lumbar region according to the tendency of the trainee. We conducted the experiments using the following protocol. Ten trainees participated in the experiment. In Phase 1, we applied loads in four directions the same number of times in random order to investigate the weak direction in the balance of each trainee. In Phase 2, we measured five trainees in each group: Group 1 was trained in the same way as Phase 1, and Group 2 was intensively trained in two directions in which the balance found in Phase 1 was difficult to maintain. In Phase 3, we performed the same experiment as in Phase 1. We analyzed the adaptation of the trainees using the margin of stability (MoS), a balance evaluation index. We compared the experimental results of Phases 1 and 3. In Group 1, the tendency for improvement in balance was unclear. On the other hand, the balance index in Group 2 improved in four out of five trainees in both the front-back and left-right directions. These results suggest that the training method concentrating on the weak direction could provide a clear directionality to the training effect.
A Remote Rehabilitation and Evaluation System Based on Azure Kinect
Authors: Wang Tai-Qi , You Yu , Osawa Keisuke , Shimodozono Megumi , Tanaka Eiichiro ,   Graduate School of Information, Production and Systems, Waseda University  2-7 Hibikino, Wakamatsu-ku, Kitakyushu, Fukuoka 808-0135, Japan,   Graduate School of Medical and Dental Sciences, Kagoshima University  8-35-1 Sakuragaoka, Kagoshima, Kagoshima 890-8544, Japan,   Faculty of Science and Engineering, Waseda University  2-7 Hibikino, Wakamatsu-ku, Kitakyushu, Fukuoka 808-0135, Japan
Published: December 2022

In response to the shortage, uneven distribution, and high cost of rehabilitation resources in the context of the COVID-19 pandemic, we developed a low-cost, easy-to-use remote rehabilitation system that allows patients to perform rehabilitation training and receive real-time guidance from doctors at home. The proposed system uses Azure Kinect to capture motions with an error of just 3% compared to professional motion capture systems. In addition, the system provides an automatic evaluation function of rehabilitation training, including evaluation of motion angles and trajectories. After acquiring the user’s 3D motions, the system synchronizes the 3D motions to the virtual human body model in Unity with an average error of less than 1%, which gives the user a more intuitive and interactive experience. After a series of evaluation experiments, we verified the usability, convenience, and high accuracy of the system, finally concluding that the system can be used in practical rehabilitation applications.
Wrapping Objects with an Automatic Contraction Ring
Authors: Mitsuda Takashi ,   Ritsumeikan University 1-1-1 Noji-higashi, Kusatsu, Shiga 525-8577, Japan
Published: December 2022

The rubber band gripper is an automatic contraction ring that is used to wrap and fix objects of various shapes by vacuuming the inside of the ring. It can be used to handle objects as a robot gripper, as well as fix bodies to pedestals, and objects to bodies. This study geometrically analyzes object shapes that can be wrapped using the ring, without causing gaps in the gripping mechanism. The analysis and experimental results show that the object shapes that can be wrapped without gaps are determined by the maximum shrinkage rate after the ring contacts the object as well as the circumference of the object. The range of object shapes that can be wrapped without gaps narrows as the object position moves away from the center of the ring. However, this influence is small, except when the object is small or has a large aspect ratio. In particular, when the object shape is cylindrical, it can be wrapped without gaps regardless of its position within the ring.
Characterization of Postural Control in Post-Stroke Patients by Musculoskeletal Simulation
Authors: Kaminishi Kohei , Li Dongdong , Chiba Ryosuke , Takakusaki Kaoru , Mukaino Masahiko , Ota Jun ,   Research into Artifacts, Center for Engineering (RACE), School of Engineering, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan,   Department of Precision Engineering, School of Engineering, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan,   Division of Neuroscience, Department of Physiology, Asahikawa Medical University 2-1-1-1 Midorigaoka-higashi, Asahikawa, Hokkaido 078-8510, Japan,   Department of Rehabilitation Medicine, Hokkaido University Hospital Kita 14, Nishi 5, Kita-ku, Sapporo, Hokkaido 060-8648, Japan
Published: December 2022

An association is observed between the standing sway posture and falls in patients with stroke; hence, it is important to study their standing balance. Although there are studies on the standing balance in stroke patients, differences in control have not been adequately investigated. This study aims to propose a method to characterize the postural sway in standing stroke patients using a mathematical model. A musculoskeletal model and neural controller model were used to simulate ten stroke patients (five patients with cerebral hemorrhages and five patients with cerebral infarctions) and eight young healthy participants, and their data were monitored during quiet standing. The model parameters were adjusted by focusing on the maximum-minimum difference in sway, which was considered important in a previous study, and sway speed, which is frequently used in the analysis. The adjusted model parameters were subjected to dimension reduction using non-negative matrix factorization. Consequently, the sway characteristics of stroke patients were expressed as the magnitude of gain parameters related to the extension of the entire body. The results of this study demonstrated the possibility of representing the characteristics of postural sway as model parameters in stroke patients using a mathematical model. This characterization could lead to the design of individualized rehabilitation systems in the future.
The Influence of Leadership, Work Environment, and Career Development on Work Achievement
Authors: Rozi Achmad Fatchur , Sumartik Sumartik
Published: December 2022

The Influence of Leadership, Work Environment, and Career Development on Work Achievement of Educational Institutions for Insan Cendekia Mandiri boarding school. This thesis is not published by the Faculty of Economics and Business, Muhammadiyah University of Sidoarjo. This study aims to determine the Influence of Leadership, Work Environment, and Career Development on Work Achievement of Independent Scholar Education Institutions. The analytical tool used is tabulating the questionnaire, collecting data in the form of validity and reliability tests. The hypotheses in this study were tested using classical assumption analysis, multiple linear regression, coefficient of determination (R2), partial correlation coefficient, t test, F test and test using SPSS for Windows version 18 software. The results of this study resulted in several conclusions, namely: ( 1) There is a simultaneous influence of Leadership, Work Environment, and Career Development on Employee Work Performance; (2) There is a partial influence of Leadership, Work Environment, and Career Development on Work Achievement; (3) Among Leadership, Work Environment, and Career Development, Career Development has the most significant effect on employee performance.
Management of Strengthening Character Education of Students during the COVID-19 Period in Elementary School Creative Schools
Authors: Masulah Uun , Wahyuni Akhtim
Published: December 2022

The management of character education strengthening is a leadership effort in planning, organizing, monitoring and evaluating student’s strengthening character, specifically during the pandemic Covid-19. The purpose of this thesis to analyze educational planning, organization, implementation and give an evaluation of the students strengthening character education during pandemic Covid-19 at Creative School of Muhammadiyah 2 elementary school 2 tulangan sidoarjo. This research used qualitative approaches with the subjects of the research are taken from the Principal, Vice-Principals, extracurricular teachers, Qur’an teachers, teachers, and Parents. This research was taken at Creative School of Muhamadiyah 2 Elementary School Tulangan Sidoarjo. Data collection techniques used in this research was interviews and observations. The data analysis technique in this research include data, reduction, data presentation and conclusion or verification. The result of this research indicate that: (1) The management planning of character education strengthening for students during the Pandemic Covid-19 at the Creative School of Muhammadiyah 2 Tulangan has implemented all the stages include planning and strategy, program socialization, administration and the learning media. (2) Organizing the students character of education strengthening during the pandemic Covid-19 at the Creative School of Muhammadiyah 2 Tulangan has been implemented by all of the stake holder to grow and achieve good habit easily. (3) The implementation of students character during the pandemic Covid-19 at the Creative School of Muhammadiyah 2 elementary school Tulangan Sidoarjo can be run quite well and effectively which is divided into 4 activities, those are: daily activities, spontaneous activities, programmed activities and exemplary activities. (4) The supervisions of students character strengthening during the pandemic Covid-19 at the Creative School of Muhammadiyah 2 elementary school Tulangan Sidoarjo has been implemented by the Principal and all of the stake holders to find out how the students character strengthening has been applied. (5) Monitoring and evaluation the management of students character education during the pandemic Covid-19 at the Creative School of Muhammadiyah 2 elementary school Tulangan Sidoarjo performed by the Principal, Vice Principal to communicate the students progress to the parents. (6) Students character during the pandemic Coid-19 at the Creative School of Muhammadiyah 2 elementary school Tulangan Sidoarjo, specially the religious character has become habit among the students On the other side, most of the good character of students have been lost and decreased
Students Perception of Erlangga Book Reader Application in Listening Skill
Authors: Safitri Elisa Bella , Santoso Dian Rahma
Published: December 2022

Globalization Era presents a fun context through the use of application technology on mobile phones as a method of learning English in listening skills. such as the use of the Erlangga book reader application on listening skills, based on student perceptions. Erlangga Book Reader is an iOS and Android-based application to play multimedia content from Erlangga Book Publishers using a QR Code. The purpose of this study was to determine students' perceptions of the Erlangga Book Reader application on listening skills. This research uses qualitative research. Data collection techniques using a questionnaire. The results showed that students' perceptions of the Erlangga Book Reader had a significant effect on students' listening comprehension, although there were some difficulties felt by students. This can be seen from the results of the questionnaire given to 3rd grade students randomly as many as 20 respondents, from 10 questions that were answered.
Management of Pregnant Women with Complaints of Increased Frequency of Urination in Clinics and Maternity Homes
Authors: Agustina Yofi Citra , Cholifah Cholifah , Azizah Nurul
Published: December 2022

Pregnancy is the stage that starts from the products of conception to the birth canal. Normal gestational age is 9 months 7 days or 40 weeks. Pregnant women are obliged to carry out ANC or pregnancy visits to health workers to detect as early as possible if there are abnormalities or complications. This care is carried out at the Afifa Maternity Clinic and Maternity Home, Prambon sub-district, Sidaorjo. Techniques for assessing data by means of patient interviews, physical examinations, analysis, documentation by comparing theories and cases in the field. The results of the report that the author did was to conduct a midwifery assessment of pregnant women with complaints of increased frequency of urination from data processing using SOAP to development. Mother complains of frequent urination in the third trimester is a physiological thing. The care carried out is by explaining the results of the examination, the causes, how to deal with it, the mother's recommendation to rest, reminding the signs of labor, preparation for delivery and pregnancy visits.
Midwifery Care for Postpartum Mothers With After Pain Discomfort in Maternity Homes and Clinics
Authors: Hafifa Hafifa , Hanum Sri Mukhodim Faridah , Rosyidah Rafhani
Published: December 2022

The postpartum period is an important period for health workers to monitor the mother's condition. The coverage of postpartum mothers' visits in 2016 was 71.54%. target coverage of postpartum mother visits in 2017 with the aim of transferring knowledge and complete postpartum visits. This type of method uses a descriptive method. whose main purpose is to make an objective picture of a situation.
Automatic Roof Control System in IoT-Based Clothes Drying Room
Authors: Yunus Novia Setya Putri , Sulistiyowati Indah
Published: December 2022

One of the problems that often occurs is that housewives are worried about their clothes getting wet in the rainy season. The automatic roof control system in the drying room is the best way to help the process of drying clothes in the rainy season. In this study, roof automation was developed using rain sensors and LDR as light detectors. NodeMCU esp3266 is also used so that the device can be controlled remotely with the Internet of Things system. The way this tool works is when the sun is hot the roof will open and when it rains the roof will close automatically, the heater and fan turn on simultaneously when the roof closes. The results of this study are the tool can detect rain and light then the heater and fan can work when the tool closes the roof with a maximum duration of 60 minutes. This tool can also operate remotely with the farthest range at 21 km.
Analysis of the Implementation of Musyarakah Financing Based on the Standard Book of Musyarakah Products
Authors: Badruzzaman Azzam , Latifah Fitri Nur
Published: December 2022

The musyarakah financing product is a competitive flagship product of Sharia Rural Banks (BPRS) which has not experienced growth like other financing products. The lack of development of musyarakah financing products has caused BPRS to have more products based on fixed income financing which is similar to the conventional pattern that uses a fixed income structure. PT. BPRS Baktimakmur Indah is the largest BPRS with assets of Rp. 163,147,899,000 and the financing provided to the community reaches Rp. 126,807,530 as of December 31, 2019. This research was conducted at BPRS Baktimakmur Indah Branch throughout Sidoarjo which is located at Jln. Raya Bebekan No.21 Throughout the Taman District, Sidoarjo Regency. The purpose of this study was to analyze the implementation of musyarakah financing based on the standard book of musyarakah products published by the financial services authority. By using qualitative research methods through a phenomenological paradigm approach that requires researching a natural setting, with observation data collection techniques, direct interviews and literature from companies to support data needs. After the research was carried out, it was found that the BPRS Baktimakmur Indah branch of the Panjang branch had implemented musyarakah financing in accordance with the standard book of musyarakah products issued by the financial services authority.
The Effect of Company Size, Profitability and Financial Laverage on Income Smoothing Practices with Good Corporate Governance as Moderating Variables in Manufacturing Companies in the Consumer Goods Industry Sector Listed on the Indonesia Stock Exchange
Authors: Nurani Etika Vira , Maryanti Eny
Published: December 2022

This research intends to know The Effect Of Company Size, Profitability and Financial Leverage To Income Smoothing Practice With Good Corporate Governance As Moderator Variable For Manufacturing Industry Consumer Goods That Registered At Indonesia Stock Exchange 2016-2018. Earlier research showing different result. Reserch is needed to re-examine the effect of two variables on income smoothing by adding good corporate governance as moderator variable. There are 53 companies in manufacturing industry consumer goods that registered at Indonesia Stock Exchange 2016-2018 research population. based on criteria purposive sampling obtained 31 companies that meet research criteria. This research is using analytical data testing SmartPLS (Partial Least Square). This research resulted in independent variables such as company size affecting income smoothing, while profitability and financial leverage are not affected by income smoothing. Good corporate governanceas a moderating potential variable (Homologiser Moderator) on the effect of company size on income smoothing, profitability  on income smoothing, financial leverage on income smoothing.
The Influence of Leadership Style, Job Training, and Compensation on Employee Job Satisfaction and Work Motivation as Intervening Variables
Authors: Harviani Nidah Emi , Harjatno Slamet
Published: December 2022

This research is a type of quantitative research with hypothesis testing. The sample used in this study were all employees of CV Bintang Tex Indonesia as many as 85 employees. The sampling technique used the total sampling method (saturated sampling). The analytical tool used in this study is a path analysis technique with the help of software for an operating system called Smart-PLS (Partial Least Square) Version 3.0. The data used in this study are questionnaire data and data sourced from CV Bintang Tex Indonesia. Data collection techniques using questionnaires, interviews, and observations. The results of this study prove that Hypothesis 1: Training and Compensation Variables have a significant effect on Job Satisfaction, while Leadership Style has no significant effect on Job Satisfaction. Hypothesis 2: Leadership Style Variable has a significant effect on Work Motivation, while Compensation has no significant effect on Work Motivation. Hypothesis 3: The leadership style variable has a significant effect on job satisfaction through work motivation as an intervening variable, while job training has no significant effect on job satisfaction through work motivation as an intervening variable, and compensation has no effect on job satisfaction through work motivation as an intervening variable.
The Effect of Job Stress, Work Environment and Compensation on Job Satisfaction with Motivation as an intervening variable at PT. Setia Kawan Grup
Authors: Mahdiana Dwi , Ubaidillah Hasan
Published: December 2022

This study aims to examine the effect of work stress, work environment, and compensation on job satisfaction with motivation as an intervening variable. The approach used in this research is a quantitative approach. The sample in this study were 70 employees at PT. Loyal Friends Group. The data used in this study is questionnaire data. Data collection techniques using questionnaires, interviews, observations, and documentation. Data analysis using software smartPLS 3.2.8. The results obtained from the path analysis showed that job stress had no significant effect on job satisfaction, job stress had a significant effect on motivation, work environment had no significant effect on job satisfaction, work environment had no significant effect on motivation, compensation had a significant effect on job satisfaction, compensation has a significant effect on motivation, motivation has a significant effect on job satisfaction, job stress does not have a significant effect on job satisfaction through the motivation variable as an intervening variable, the work environment does not have a significant effect on job satisfaction through the motivation variable as an intervening variable, compensation has a significant effect on job satisfaction through motivation variable as an intervening variable. Keywords: Job Stress, Work Environment, Compensation, Job Satisfaction, Motivation.
Phonology of Molla Yâr Muhammed Nemengâni and Tuhfetü-l Abidin
Authors: Barlas Hairatullah
Published: December 2022

As a master degree graduate thesis, we selected the Tuhfetüʾl-ʾÂbidîn. It is a collection of the poems written by Molla Yur Muhammed Nemengânî who was born in the 19th century in Nemengân. There are many poems from different poets in the book which consisting of 188 pages, but 108 pages belongs to our poet Nemengânî and this study focused on these pages.  in the poems, poet was known by his surname, Muhlis. The text was found in Hoyham village in Badakhshan province, which is located on the borders of Afghanistan. The texts of the book have been transcribed and translated into Latin alphabets. Considering language characteristics, writing characteristics, phonetic features and shape characteristics, the texts were studied.
Importance and Prospects of Viticulture in Surkhandarya Region
Authors: Farkhodovich Rakhmatov Abdukholik , Uglu Olimkulov Yashnar Mahmadamin
Published: December 2022

This article describes the attention paid to viticulture in the country and its prospects, the ongoing projects in Surkhandarya region, especially in Altynsay district, the viticulture sector in the district, the processing of grapes and the production of products for the needs of our people. In conclusion, it is noted that the study of the characteristics of grapes and the experience of foreign countries in the development of the industry is very effective.
Use of Graphics Processors in Data Compression Algorithms
Authors: Uchkunovna Khalilova Shahnoza
Published: December 2022

Query co-processing on graphics processors (GPUs) has become an effective means to improve the performance of main memory databases. However, this co-processing requires the data transfer between the main memory and the GPU memory via a lowbandwidth PCI-E bus. The overhead of such data transfer becomes an important factor, even a bottleneck, for query co-processing performance on the GPU. In this paper, we propose to use compression to alleviate this performance problem.
ANALYSIS AND DIFFERENT INTERPRETATIONS OF THE CONCEPT OF SPIRITUALITY
Authors: Akhmedova Mekhrinigor Bahodirovna
Published: December 2022

The article provides general information about the concept of spirituality, and opinions on the analysis of the concept of spirituality. However, the analysis and different interpretations of the concept of spirituality are deeply analyzedand based on ideas using examples.
Aesthetics of Theory in the Modernist Era
Authors: Bakoeva Saodat Shuhratovna
Published: December 2022

the article provides an overview of the aesthetics of modernist literature. However, there are also many ideas about the aesthetics and psychologicalprocess of modernist literature. There are also analyses through examples of the aesthetics of theory in the modernistic period.
A Description of the Artistic Image of the Works of Guy de Mopassan and Abdullah Qadiri
Authors: Jabbarova Malohat Hamdamovna
Published: December 2022

The article provides an overview of the artistic analysis of the works of Guy de Mopassan and Abdullah Qadiri. At the same time, the works of the creatorswere analyzed using comprehensive examples. There is also a discussion of the artisticmeans used in the works.
Explanation of Agricultural Terms in Dictionaries
Authors: Sumaira Nawaz,  , Khaitova Gulshan Bahodirovna  , Akhmedova Mehrinigor Bahodirovna
Published: December 2022

The article is devoted to the agrarian terminology of the German and Uzbek languages, their formation, linguistic analysis, linguistic and cultural features and their place in the terminological system.
The Role of Poetic Style In Correcting Phonetic Pronunciation: From Poetic Play To Phonetic Play
Authors: Abdullaeva Nilufar
Published: December 2022

One of the important tasks at any stage of teaching a foreign language, including French, is to maintain and improve pronunciation skills. The phonetic process that facilitates the formation of such skills is rhyme.
Russian as a Foreign Language: Teaching Reading
Authors: Akhmedov B.Y.
Published: December 2022

Reading is one of the types of speech activity associated with the perception and comprehension of written speech. However, reading contributes to thedevelopment of all types of speech activity. We rely on reading in the developmentand improvement of listening and speaking skills, in teaching students writing.
Semantic Properties of Anthroponyms
Authors: Nazarova Navbahor Ahrorovna
Published: December 2022

This article discusses the lexical-semantic features of anthroponyms, their origin and etymology as well. Anthroponyms have also been analyzed on the example of some names.
Results Of Using Lateral Surgical Approaches In The Surgical Treatment of Tuberculosis Spondylitis of the Lumbar and Lumbosacral Spine
Authors: Usmonov Isomiddin  Haydarovich  , Pardaev Muxammadjon Jumanazarovich
Published: December 2022

The work is based on the survey data of 190 patients with tuberculosis spondylitis (TS) of the lumbar and lumbosacral spine, who underwent surgical intervention using traditional lateral access. In 158 (83.2%) patients, radical reconstructive surgery (RRS) was performed in the lumbar, and in 32 (16.8%) cases - lumbosacral spine. Of these, 127 (66.8%) patients of the affected segment underwent spinal fusion using a titanium mesh cage (Piramesh), and 63 (33.2%) using the traditionally classical method with auto bone fusion. The use of traditional lateral access allows the surgeon to fully work in the lumbar spine, but with lesions of the lumbosacral spine, the possibility of detecting VL5, VS1-2 bodies is difficult and dangerous. Damage to muscles, nerves and blood vessels of the abdominal wall, often encountering postoperative complications such as muscle prolapse, abdominal wall hernia, discomfort, and rough scar are considered to be the main disadvantages of lateral access in RVO of the lumbar and lumbosacral spine.
Conceptual Metaphor and Polysemy
Authors: Nigora Sobir qizi Jumaboyeva
Published: December 2022

This article deals with the conceptual metaphor and polysemy. Author tries to prove polysemy, which, along with conceptual metaphor, is one of the main mental processes, becomes a catalyst for the development of meaning and the generation of new meanings, and the possibility of its appearance is due to the anthropocentrism of communication itself and human experience. In addition, author provides several notions of prominent linguists who contributed in the sphere of metaphor and polysemy.
Database in Land Resource Management.
Authors: SH.Y.Sattorov  , A.M.Abdulloyev  , A.B.Ochilov  , T.A.Ismatov
Published: December 2022

This article discusses the current importance of databases and land databases in land resource management.
Ecological Significance of Laser Leveling of Lands.
Authors: A.M.Abdulloyev  , A.B.Ochilov  , A.B.To’xtamishov
Published: December 2022

The economic efficiency of laser leveling of lands is that in Uzbekistan the cultivation of agricultural crops is based on irrigated agriculture, where 90-95% of the crop is grown. Caring and cultivation of crops is carried out by applying several agro-technical measures, the most important of which is land leveling. In agriculture, the main purpose of land leveling is to carry out irrigation and mechanized agro-technical measures while maintaining the slope of the field.
Importance of Remote Sensing Data in The Study of Land Resources
Authors: SH.Y.Sattorov  , A.M.Abdulloyev  , A.B.Ochilov  , A.B.To’xtamishov
Published: December 2022

This article discusses the importance of remote sensing data in the study of land resources, through which the current production process is carried out directly
The Attitude of the Population To Tourism, The Impact Of Domestic Tourism On Women's Employment
Authors: Ashurov Bahtiyor Iskandarovich
Published: December 2022

This study examines whether the socio-demographics of the local population and public relations can influence their impact on tourism (economic, environmental and socio-cultural impacts), as well as their satisfaction with local tourism management. Checks the impact and prospects of tourism in the employment of the population in need of social protection, mainly women. At the same time, key issues leading to gender inequality will be discussed. According to a survey of local residents, attitudes towards tourism and the requirements of domestic tour packages were assessed.
The Most Important Aspects Of The Democratic Governance Style In The Modern Human Resources Management System
Authors: Iroda Bakiyeva  , Sarvar Rustamov
Published: December 2022

The modern human resources management system requires a manager to feel highly human. Therefore, research is a dose. The article analyzed the comparison of management styles and made conclusions through deductive methods.
Impact Of Economic Digitalization On Labor Market Subjects
Authors: Babakulov Bahrankul Mamatkulovich  , Mirzaxodjayev Alisher Botirovich
Published: December 2022

In the context of digitalization, it is important to determine the characteristics of the labor market. This is because identifying the impact of digitalization on the labor market, highlighting its pros and cons, and eliminating the risk to labor relations provide an opportunity to address the unemployment caused by digitalization.
Digitization of Labor Relations
Authors: Mirzaxodjayev Alisher Botirovich
Published: December 2022

In the context of digitalization, it is important to determine the characteristics of the labor market. This is because identifying the impact of digitalization on the labor market, highlighting its pros and cons, and eliminating the risk to labor relations provide an opportunity to address the unemployment caused by digitalization.