bluuebunny/crossref_metadata_2025 huggingface dataset:
The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix
Authors: Taylor Scott , Whitfield Molly , Barratt Jonathan , Didangelos Athanasios
Published: September 2020

In IgA nephropathy (IgAN), IgA immune complexes are deposited in the mesangium and drive inflammation and extracellular matrix (ECM) remodelling. The functional links between IgA deposition, inflammation, and matrix remodelling are not well characterized. We recently performed urine liquid chromatography–tandem mass spectrometry proteomics and identified multiple ECM glycoproteins whose expression and function in IgAN is unclear. None of the urine glycoproteins was regulated in IgAN transcriptomics, indicating that tissue remodelling rather than increased expression might contribute to their presence in urine. To investigate this, we examined the IgAN expression profile of metalloproteinases, enzymes involved in the remodelling of ECM proteins, and noted that the proteoglycanase ADAMTS5 was upregulated in IgAN kidneys. ADAMTS5 accumulated in areas of inflammation, and ADAMTS5+ cells were seen in the tubulointerstitium and glomeruli. The enzyme was expressed by CD64+ cells and its expression was increased by IL-1 and LPS. Analysis of myeloid cell transcriptomics revealed that ADAMTS5 is enriched in human classical monocytes. ADAMTS5+ cells were present in areas of matrix remodelling and associated with ECM proteins lumican, versican, and collagen-4. Liquid chromatography–tandem mass spectrometry proteomics of kidney explants digested with ADAMTS5, identified multiple kidney proteins affected by ADAMTS5 and revealed specific proteolysis of complement C3 and fibronectin associated with IgA on immune complexes. ADAMTS5 processing of immune complex proteins reduced binding to cultured mesangial cells. ADAMTS5 is associated with interstitial inflammatory cells in IgAN and other kidney lesions and fragments relevant extracellular proteins. The proteolytic enzyme might be a new translational target relevant to inflammation and scarring in kidney disease.
Interpreting discordance on dual-tracer positron emission tomography–computed tomography in the setting of metastatic neuroendocrine tumor: Detection of metachronous triple-negative breast carcinoma
Authors: Kalshetty Ashwini , Basu Sandip
Published: September 2020

Second primary malignancies (SPMs) are known to be associated with neuroendocrine tumors (NETs). The association necessitates a careful assessment of the dual-tracer positron emission tomography–computed tomography (PET-CT) imaging findings to identify these malignancies earlier. Such early diagnosis can provide incremental benefit for screening these SPMs apart from their known applications in the management of NETs. A case of incidentally detected metachronous triple-negative breast carcinoma on dual-tracer PET-CT imaging is presented using 18fluoro-2-deoxy-D-glucose (FDG) and 68Ga-DOTATATE that showed a high uptake on FDG but no uptake on somatostatin receptor-based imaging.
The findings of 18F-fluorodeoxyglucose positron emission tomography–computed tomography scan in patients with hidradenitis suppurativa in Malaysia: A multicenter study
Authors: Loo Chai , Khoo Alex , Tan Wooi , Khor Yek , Tang Jyh , Tang Min , Chan Lee
Published: September 2020

Hidradenitis suppurativa (HS) is known to have association with systemic diseases with chronic inflammation such as psoriasis. We aim to describe the concomitant systemic inflammation in patients with HS using 18F-fluorodeoxyglucose positron emission tomography–computed tomography (18F-FDG PET/CT) scan. This was a case–control study conducted in three tertiary hospitals in Northern Malaysia from January to December 2017, involving HS patients aged 18 years and above. Thirty-two HS patients with age- and sex-matched controls were recruited with a mean age of 31.4 years (range: 18–56). Numerous cutaneous inflammatory foci were detected on FDG-PET/CT scan in clinically unapparent sites (27/32, 84.4%). Approximately 90.6%, 93.8%, and 50.0% of the patients had significantly higher cutaneous uptake over nasal, mandibular, and scalp regions, respectively (P < 0.0001). PET/CT scan did not detect any systemic inflammation unlike those found in psoriasis. Three (9.4%) patients had thyroid nodules with high uptake (maximum standard uptake values ranging from 2.9 to 11.3). Two of them were confirmed to have papillary thyroid carcinoma, while the third patient has inconclusive finding. 18F-FDG PET/CT scan may be useful to map disease burden of HS. Nonlesional inflammatory foci on the skin of the nose, mandibular, and scalp are probably significant. The association of thyroid carcinoma in HS warrants further evaluation.
Comparison of noise estimation methods used in denoising 99mTc-sestamibi parathyroid images using wavelet transform
Authors: Pandey Anil , Sharma Param , Sharma Akshima , Bal Chandra , Kumar Rakesh
Published: September 2020

The objective of this study was to compare the performance of variance, median absolute deviation, and the square of median absolute deviation methods of noise estimation in denoising of 99mTc-sestamibi parathyroid images using wavelet transform. Sixty-eight 99mTc-sestamibi parathyroid images including 33 images acquired at zoom 1.0 and 35 acquired at zoom 2.0 were denoised using the wavethresh package in R. The image decomposition and reconstruction method discrete wavelet transform, wavelet filter db4, shrinkage method hard, and thresholding policy universal were used. The noise estimation in the process was made using var, mad and madmad functions, which use variance, mean absolute deviation, and the square of mean absolute deviation, respectively. The quality of denoised images was assessed both qualitatively and quantitatively. A nonparametric two-sample Kolmogorov–Smirnov test was applied to find whether the difference in image quality produced by these three noise estimation methods was significant at 95% confidence. Noise estimation using madmad function produced the best quality denoised image. Further, the quality of the denoised image using madmad function was significantly better than the quality of the denoised image obtained with var or mad function (P = 1). The estimation of noise using madmad functions in wavelet transforms provides the best-denoised image for both zoom 1.0 and zoom 2.0 99mTc-sestamibi parathyroid images.
Attenuation correction in single-photon emission computed tomography for NURBS-based cardiac-torso phantom using dual-energy acquisition
Authors: Rajabi Hossein , Ahangari Hadi , Mohammadi Iraj , Mohammadkarim Alireza , Tajik-Mansoury Mohammad
Published: September 2020

Single photon emission tomography is widely used to detect photons emitted from the patient. Some of these emitted photons suffer from scattering and absorption because of the attenuation occurred through their path in patient's body. Therefore, the attenuation is the most important problem in single-photon emission computed tomography (SPECT) imaging. Some of the radioisotopes emit gamma rays in different energy levels, and consequently, they have different counts and attenuation coefficients. Calculation of the parameters used in the attenuation equation Nout=αNin= e−
μ
l Ninby mathematical methods is useful for the attenuation correction. Nurbs-based cardiac-torso (NCAT) phantom with an adequate attenuation coefficient and activity distribution is used in this study. Simulations were done using SimSET in 20—70 and 20—167 keV. A total of 128 projections were acquired over 360°. The corrected and reference images were compared using a universal image quality index (UIQI). The simulation repeated using NCAT phantom by SimSET. In the first group, no attenuation correction was used, but the Zubal coefficients were used for attenuation correction in the second image group. After the image reconstruction, a comparison between image groups was done using optimized UIQI to determine the quality of used reconstruction methods. Similarities of images were investigated by considering the average sinogram for every block size. The results showed that the proposed method improved the image quality. This study showed that simulation studies are useful tools in the investigation of nuclear medicine researches. We produced a nonattenuated model using Monte Carlo simulation method and compared it with an attenuated model. The proposed reconstruction method improved image resolution and contrast. Regional and general similarities of images could be determined, respectively, from acquired UIQI of small and large block sizes. Resulted curves from both small and large block sizes showed a good similarity between reconstructed and ideal images.
Unusual location of recurrent mantle cell lymphoma on fluorodeoxyglucose-positron emission tomography despite complete metabolic resolution of previous sites of disease
Authors: Froitzheim Benjamin , Boktor Raef , Lau Eddie , Lee Sze
Published: September 2020

This case report presents a patient with recurrent pleomorphic mantle cell lymphoma (MCL), which is a relatively rare but aggressive type of lymphoma. A positron emission tomography/computed tomography scan performed to assess treatment response demonstrated a complete metabolic response in the sites of primary disease while also revealing new subcutaneous lesions, which were biopsy-proven recurrent disease. This case illustrates the importance of the different biological behavior of MCL, whereby new sites of metabolically active lesions can represent recurrent disease, even though there is a complete metabolic response at sites of primary disease.
Rapidly lethal secondary hemophagocytic lymphohistiocytosis predicted by fluorodeoxyglucose positron-emission tomography/computed tomography
Authors: Makusha Lovemore , Pucar Darko , Young Colin
Published: September 2020

Secondary hemophagocytic lymphohistiocytosis (sHLH) is a rare disease with either an indolent or aggressive course. A 29-year-old male presented with fever, polyarthralgias, splenomegaly, retroperitoneal adenopathy, and laboratory findings consistent with Epstein—Barr-mediated sHLH. Consistent with a prior survival analysis by Kim et al., splenic maximum standardized uptake value (SUVmax) >2.52 and bone marrow SUVmax>3.13 on 18F-fuorodeoxyglucose positron emission tomography/computed tomography (18FDG-PET/CT) predicted an aggressive disease with poor treatment response. Despite optimal treatment, the patient rapidly progressed to death within 3 months of symptom onset. This case underscores the potential lethal nature of sHLH, and the evolving role of 18FDG-PET/CT in predicting disease severity and treatment response.
18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures
Authors: Claimon Apichaya , Tantranont Ngoentra , Claimon Torpong
Published: September 2020

Adrenal cortical carcinoma (ACC) is a rare aggressive endocrine tumor with poor prognosis. About 60% of ACC are functional tumors. Bilateral ACC is extremely rare, roughly 2%—10% of cases. Diagnosis and staging of ACC by imaging modalities are crucial for preoperative planning and prognostication. Detection of hyperfunctional bilateral adrenocortical carcinoma by 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F- FDG PET/CT) has never been reported. Herein, we report a male patient who presented with Cushing's syndrome, type II diabetes mellitus due to Cushing's syndrome, and hypogonadism with biopsy confirmed left ACC. He underwent 18F-FDG PET/CT to evaluate the contralateral adrenal mass and to plan for laparoscopic adrenalectomy, which subsequently confirmed bilateral ACC. Furthermore,18F-FDG PET/CT was useful in staging, which revealed paraaortic lymph node and lung metastasis.
Genetic Characterization Based on Rapd-Pcr in Cultured Strains of Clarias gariepinus (Siluriformes: Clariidae)
Authors: Adesola Ola-Oladimeji Folasade , Awodiran Michael Olufemi , Olaleye Victor Folorunso , Awopetu Joel Idowu
Published: September 2020

The genetic polymorphisms of catfish populations collected from four fish farms in four Southwestern states of Nigeria were determined by Randomly Amplified Polymorphic DNA Polymerase Chain Reaction technique. This was to characterize the strains genetically and provide information on the studied catfish. Following standard procedures, polymerase chain reaction was performed by mixing 15 μl reaction mixture containing FIREPOL® Taq DNA polymerase, MgCl2, dNTPs, distilled water, dyes and glycerol, with 1.0 μl DNA sample of 16-week old C. gariepinus strains using OPA03, OPA04, OPC02, OPB08, OPC11, OPG16, OPG19 and OPA19 primers. A sum of 1708 loci having 3072 bands was amplified in all the samples. The RAPD analysis revealed significant genetic variability (P<0.05) among the four sampled populations. The unweighted pair group method with average (UPGMA) dendrogram based on Nei’s unbiased genetic distance matrix separated the Clarias gariepinus populations into two clades. The first clade was made up of populations from Ibadan and Abeokuta while the second clade consisted of populations from Ado-Ekiti and Ile-Ife. Thus, it is imperative to determine the genetic variation and population structure of the stocks of C. gariepinus in advance before commencing on breeding programmes.
Modernizing the Philosophy of Creative Creativity
Authors: Rošker Jana S.
Published: September 2020

Fang Dongmei (1899–1977) is among the most influential Chinese philosophers who lived and worked in Taiwan during the second half of the 20th century. The present article aims to clarify his view on the basic nature of the human Self. This assessment is more multifaceted than it seems at a first glimpse, for Fang’s philosophy is also more complex than it seems. As a member of the so-called neo-conservative streams of thought, he criticized the Western-type modernization and aimed to revive the holistic onto-epistemology of classical Confucianism. On the other hand, he highlighted the importance of its basic paradigm which underlay the Confucian discourses from their very beginning, i.e. since the Book of Changes, namely the principle of creative creativity (shengshengbuxi 生生不息). The alleged contradiction between his advocating of holism and creativity, has been reflected in the apparent dichotomy between the social and relational essence of the Confucian Moral Self on the one side, and individual uniqueness on the other. The paper aims to show that both seeming contradictions are actually parts of the same theoretical principle defining the complementary interactions of binary oppositions.
Mapeamento das dissertações sobre Modelagem Matemática produzidas no Mestrado Profissional em Matemática em Rede Nacional
Authors: Almeida Moisés Ceni de , Musmanno Leonardo Maricato , Sousa Sérgio Gonçalves de
Published: September 2020

O artigo apresenta um mapeamento quanti-qualitativo das dissertações elaboradas no Mestrado Profissional em Matemática em Rede Nacional (PROFMAT) produzidas nos últimos sete anos, cujo objeto de estudo tenha abordado Modelagem Matemática. O objetivo desse mapeamento foi obter, no âmbito quantitativo, uma visão geral das pesquisas nas dissertações e, qualitativamente, se abordam o tema dentro de uma perspectiva de metodologia de ensino. O mapeamento identificou os conteúdos mais abordados e a distribuição das produções por nível de escolaridade, ano de publicação, regiões, estados e instituições, permitindo verificar a evolução dos trabalhos e possíveis lacunas. Foram investigadas 140 dissertações sobre Modelagem Matemática e sua aplicação, teórica e prática, em todos os níveis de ensino, incluindo na formação continuada de professores de Matemática. Percebe-se que há aumento das produções nos últimos anos, em sua maioria, apresentando temas direcionados ao Ensino Médio, sem discutir, contudo, a importância da Modelagem Matemática como ferramenta de ensino.
Palavras-chave: Modelagem Matemática. Educação Matemática. PROFMAT.
PENGARUH MODERNISASI TERHADAP BAHAN BANGUNAN HUNIAN TRADISIONAL DI DESA ADAT TENGANAN, KABUPATEN KARANGASEM, BALI
Authors: Indra I Gede Bagus Rae
Published: September 2020

Tenganan Traditional Village is a Bali Aga Village located in Karangasem Regency. As a cultural village tourism object, Tenganan Traditional Village is unique in the form of a spatial arrangement pattern with unique traditional building architecture, traditions and cultural activities of the community, as well as villagers' handicrafts such as woven or bamboo, carvings, and paintings on palm leaves as well as gringsing woven fabric. In line with the times and the rapid development lately there have been concerns about the continuation of development in the Tenganan Traditional Village, resulting in many changes to the residential buildings, especially in building materials. The condition of the Traditional Village which has started to leave materials for traditional buildings and switch to modern building materials. These changes caused the loss of the traditional values of the Tenganan people which became the core of the local community architecture. So it needs special attention and efforts in preserving the architectural values of traditional Tenganan houses. So that the existence of traditional houses and the uniqueness of the village can be maintained and still show the traditional values of the traditional houses of Tenganan Village, with new buildings that will be occupied by the community. Some things that have experienced the influence of modernization are in terms of roof, wall and bataran building materials. This requires joint efforts by the government and local communities to preserve the development of traditional houses related to traditional traditions in the Tenganan Traditional Village so that the construction of traditional houses is sustainable.
KARAKTERISTIK BANGUNAN “BALE PIYASAN” SERTA PROSES PEMBANGUNANNYA
Authors: Prayatna Agus Eru , Widiyani Desak Made Sukma
Published: September 2020

Bale Piyasan is one type of sacred building for the Hindu community, especially in Bali as an ancestral heritage that needs to be developed and preserved, so we need to know the background of the Bale Piyasan design and at the same time to know the historical and cultural values contained therein.  At the same time as a comparison between the opinions of the sources and the reality in accordance with the conditions in the field, case studies which have different characteristics are carried out, both in terms of function, layout and shape of the sacred building.  Based on this description, the purpose of this research is to find the meaning of the philosophy of the Bale Piyasan building, to find the process of self-reliance and physical, the rituals in constructing the Bale Piyasan and to determine the layout of the Bale Piyasan building as well.  This research is a comparative descriptive study, where physical and non-physical data are collected, both library and field data. From the results of the analysis and comparison, they are reviewed and concluded to obtain a recommendation.  There are 2 (two) types of data used in this study, namely primary data and

secondary data.  Primary data is obtained through (1) surveys and observations, namely making direct observations to objects and carrying out documentation, (2) interviews, which are conducted with people who are competent and can be trusted in this matter.  Secondary data includes literature studies conducted to find information about research through information sources such as books, reports, the internet.  From the results of literature and factual studies and analysis results, it can be concluded that Bale Piyasan is a rectangular elongated building with 4 (four) poles as a place to decorate or assemble symbols before being distributed to the sacred building and the place where the ceremony will be offered.  Bale Piyasan functions as a place to decorate or arrange symbols, such as Daksina Pelinggih or Arca. The layout of Bale Piyasan is on the west side facing south.  We can find Bale Piyasan in the innards of the temple.  The Bale Piyasan design uses elbows or traditional Balinese measurements. The establishment of Bale Piyasan must follow the processes and ceremonies in accordance with the rules of traditional Balinese architecture.
EMPLOYEE PERSPECTIVE ON COMPANY LEADERS: BETWEEN DISCIPLINE AND JOB SATISFACTION
Authors: Vipraprastha Tiksnayana , Rihayana I Gede , Andika Ary Wira
Published: September 2020

The purpose of this study was to examine the influence of the role of leadership and work discipline on employee performance with job satisfaction as an intervening variable at PT. Sarana Arga Gemeh Amerta Denpasar. The sample in this study were employees of PT. Sarana Arga Gemeh Amerta Denpasar as many as 112 respondents. The analysis tool used is path analysis (path analysis). The results of the analysis explain that the leadership and work discipline variables have a positive and significant effect on employee performance, in addition to directly affecting employee performance, this variable is also influenced by job satisfaction as an intervening variable where it can be explained that job satisfaction as an intervening variable that connects leadership and work discipline variables has results. partially positive significant towards employee performance. This means that job satisfaction is not fully a benchmark in determining employee performance, because the results of this study state that the role of the leader in paying attention is needed by employees and work discipline becomes employee guidance in completing a job that is the responsibility of each employee.

 Article visualizations:
Propiedad y pobreza colectiva en san Ignacio y Suárez
Authors: Elorduy Eleuterio
Published: September 2020

El estudio, escrito en los primeros años 1960 e inédito hasta hoy, trata sobre la pobreza y la propiedad en la tradición jesuita. Tras una breve introducción filosófico-social y una aproximación histórico-jurídica a la cuestión de la pobreza colectiva en la Iglesia, a continuación se trata de la cuestión de los bienes eclesiásticos y exponer de la pobreza en la Compañía de Jesús, para en apartados sucesivos el pensamiento de san Ignacio y el de Francisco Suárez sobre la pobreza colectiva. Unas breves conclusiones, referidas a los primeros apartados no específicamente jesuitas, cierran el estudio. A partir de la espiritualidad y del pensamiento de san Ignacio, recogido en las Constituciones de la Compañía de Jesús y en algunas actuaciones suyas, y de la posición doctrinal de Francisco Suárez con ocasión de la fundación real del colegio jesuita de Salamanca, así como ante la tercera congregación general jesuita en 1608, el autor concluye que tanto uno como otro concebían la pobreza, y en relación con ella la propiedad, de acuerdo con la doctrina común de la Iglesia de entonces, aunque superando la tensión entre institucionalistas y funcionalistas. Para ambos, la pobreza de la Compañía de Jesús es la propia de una institución carismática en la que los bienes son concebidos sólo como instrumentos de Dios. A ese fin –el de ser meros instrumentos divinos–tienden tanto la espiritualidad ignaciana como el pensamiento suareciano.
In Ieremiam (1591)
Authors: Alcázar Luis del , Navas Gutiérrez Antonio M.
Published: September 2020

.
Antonio de Rojas, sus obras, su condena, sus «poesías místicas» y el soneto «No me mueve, mi Dios, para quererte»
Authors: Verd Conradi Gabriel María
Published: September 2020

El presbítero madrileño Antonio de Rojas fue el primero que publicó en letra impresa el famoso soneto No me mueve, mi Dios, para quererte, en una obra titulada Vida del espíritu, aparecida en Madrid en 1628. Fue reeditada varias veces en español y tuvo una importante repercusión en Europa por medio de sus traducciones al francés, al italiano, al alemán y al flamenco.Pero fue incluida en el Index librorum prohibitorum porque se consideró que su doctrina sobre la oración estaba contagiada de quietismo. En estas páginas se identifica a la persona, se reseñan sus obras, ediciones y traducciones, se expone su inclusión en el Índice, su posible relación con el quietismo, la autoría de las poesías que insertó en sus obras y su relación con el célebre soneto, sobre el que en ATG han parecido otros estudios recientemente (2004, 2005, 2006, 2007, 2008, 2012, 2013, 2014, 2015 y 2016).
Compañía de Jesús e islam en España (siglos XVI-XVII)
Authors: Medina Francisco de Borja
Published: September 2020

El estudio presenta sintéticamente un estado de la cuestión sobre la investigación reciente de las relaciones entre los jesuitas y el islam en la España moderna. Para ello se abordan sucesivamente las cuestiones de la conversión de los moriscos, de los jesuitas de esa procedencia étnico-religiosa, principalmente Juan de Albotodo e Ignacio de las Casas, y finalmente de la actuación apostólica en el norte de África y en España con cautivos, esclavos y comerciantes. En un segundo momento trata de la problemática que ese ministerio planteaba a la naciente Compañía, apuntando a ciertos elementos innovadores en la teología de la misión como la necesidad, sentida especialmente por de las Casas, de un mayor conocimiento de la cultura islámica y de los estudios coránicos. En un último apartado se trata de la famosa cuestión de los conocidos como “libros plúmbeos del Sacromonte” que plantea el sincretismo islamo-cristiano (cfr. F. J. Martínez Medina, Cristianos y musulmanes en la Granada del siglo XVI, una ciudad intercultural. Intervenciones de reliquias y libros plúmbeos: el Sacromonte, Granada 2016, BTG n. 42).
EFFECTIVE MANAGEMENT OF HOSPITAL AND MEDICAL WASTE IN RURAL AREAS OF PAKISTAN: A CASE STUDY
Authors: Sadia Anam
Published: September 2020

The proper management and safe disposal of increasing amount of solid wastes has been recognized as a global problem of the recent age. Toxic and hazardous constituents present in the solid wastes, make this problem even more critical and challenging. Exposure of such solid waste, when not managed properly significantly effects the local environment and public health. For example, bio-hazardous wastes generated from hospital and other clinical settings possess heterogeneous constituents with potentially infectious properties imposing a significant threat to the public health as well as the natural environment. This becomes more curious in case of epidemic diseases treatment and cure procedures. There are several techniques used to treat the infectious wastes, however, adoption of either technique depends upon the type of material and available resources. Thermal treatment or incineration has been found as one of the common and efficient methods for toxic waste management in which waste materials are ignited and burnt under controlled conditions destroying the toxic constitutes of the hazardous materials. The present study has been taken up in order to study the toxic waste management with emphasis on hospital waste. The case of basic health unit has been taken in order to assess and quantify toxic waste potential and its management. The study has also come up with a proposed design of small-scale fixed bed incinerator for hospital waste.
Statistical inference for Kumaraswamy-exponential distribution based on progressive Type-II censored data with binomial removals
Authors: MOHAN RAKHI , CHACKO MANOJ
Published: September 2020

In this paper, estimation of parameters of Kumaraswamy-exponential distribution with shape parameters α and β is considered based on a progressively type-II censored sample with binomial removals. Together with the unknown parameters, the removal probability p is also estimated. Bayes estimators are obtained using different loss functions such as squared error, LINEX loss function and entropy loss function. All Bayesian estimates are compared with the corresponding maximum likelihood estimates numerically in terms of their bias and mean square error values and found that Bayes estimators perform better than MLE’s for β and p and MLEs perform better than Bayes estimators for α. A real data set is also used for illustration.
Inference on mean quality-adjusted lifetime using joint models for continuous quality of life process and time to event
Authors: GAO XIAOTIAN , DONG XINXIN , KANG CHAERYON KANG , WAHED ABDUS S.
Published: September 2020

The estimated average treatment effect in observational studies is biased if the assumptions of ignorability and overlap are not satisﬁed. To deal with this potential problem when propensity score weights are used in the estimation of the treatment effects, in this paper we propose a bootstrap bias correction estimator for the average treatment effect (ATE) obtained with the inverse propensity score (BBC-IPS) estimator. We show in simulations that the BBC-IPC performs well when we have misspeciﬁcations of the propensity score (PS) due to: omitted variables (ignorability property may not be satisﬁed), overlap (imbalances in distribution between treatment and control groups) and confounding effects between observables and unobservables (endogeneity). Further reﬁnements in bias reductions of the ATE estimates in smaller samples are attained by iterating the BBC-IPS estimator.
RANCANG BANGUN SISTEM PEMANGGILAN DARURAT PASIEN BERBASIS WEB MENGGUNAKAN MIKROKONTROLER
Authors: Permana Eka - , Wijayanti Dini
Published: September 2020

Rumah sakit adalah sebuah asosiasi perawatan kesehatan yang kompleks, padat profesi dan padat modal. Kompleksitas ini muncul karena pelayanan rumah sakit terkait dengan berbagai fungsi pelayanan, pendidikan dan penelitian juga mencakup berbagai tindakan serta disiplin medis. Agar rumah sakit dapat menjalankan fungsi yang demikian kompleks, rumah sakit harus memiliki sumber daya manusia yang baik dalam bidang teknis medis maupun administrasi kesehatan. Terkait masalah yang mengaharapkan ada pelayanan kesehatan yang kurang efisien yaitu dibutuhkan sistem yang dapat digunakan dalam sistem penanganan darurat pasien, Diperlukan sistem yang dapat membantu rumah sakit terhadap pasien Diperlukan yang mendukung dengan rumah sakit tersebut atau dengan desain yang keras atau sistem yang mendukung rumah sakit, yang dapat membantu rumah sakit untuk membantu pasien yang membutuhkan pertolongan dengan cepat, karena sistem ini akan sangan efisien, Alat yang menujang dalam pembatan aplikasi ini yaitu menggunakan mikrokontroler dan editor yang digunkan dalam pembuatannya adalah notepad ++. Dari hasil pembahasan tentang sistem dan implementasi terhadap pasien rumah sakit maka mengahasilkan manfaat yang memang cukup signifikan diterima oleh pasien dan juga perawat juga dokter. Harapan nya semoga aplikasi ini bisa di pakai dan di manfaatkan dengan sebaik mungkin, agar bisamembantu rumah sakit.
SISTEM INFORMASI PERPUSTAKAAN BADAN PUSAT STATISTIK KABUPATEN SUBANG BERBASIS PHP
Authors: Supriatna Ade , Hakim M Azizul
Published: September 2020

Sistem Informasi adalah data yang telah diproses dan memiliki banyak kegunaan. Dalam hal ini adalah data yang diberikan terdiri dari sistem informasi perpustakaan yang digunakan untuk memfasilitasi peminjaman buku yang merupakan sumber dari ilmu pengetahuan. Di Perpustakaan Badan Pusat Statistik Kabupaten Subang, para peminjam atau anggota dapat memperoleh informasi tentang koleksi yang tersedia diperpustakaan dengan mudah. Selain itu dalam proses peminjamannya yang semula dilakukan secara manual, sekarang dapat dilakukan secara komputerisasi. Dengan begitu proses peminjaman dapat dilakukan dengan cepat dan mudah terstruktur. Begitu juga dengan sistem dikembalikannya dilakukan dengan mudah, cepat dan efisien. Pembuatan laporan semula masih bersifat manual yaitu dengan cara melakukan rekapitulasi dari transaksi yang terjadi, setelah adanya sistem informasi yang kami buat proses pembuatannya dapat dilakukan dengan mudah. Dengan adanya sistem informasi ini dapat memudahkan proses pembayaran dan peminjaman buku serta dapat menghasilkan laporan yang lebih cepat dan akurat.
REKOMENDASI PEMASARAN KENDARAAN BERMOTOR RODA DUA MENGGUNAKAN ALGORITMA K-MEANS CLUSTERING BERBASIS GEOSPASIAL
Authors: Suryadi Usep Tatang , Meilawati Lina
Published: September 2020

Pada tahun 2013, jumlah angkutan alat transportasi umum dan luas daerah di Kabupaten Subang adalah 661: 2052. Dengan jumlah kendaraan yang tidak layak guna sebanyak 396 kendaraan atau 60% dari total. Data KOPJAS pada 2018, jumlah trayek / rute angkutan umum sebanyak 420 trayek / rute, sedangkan jumlah trayek / rute elf sebanyak 227 trayek / rute. Jadi, total seluruh trayek / rute di Kabupaten Subang sebanyak 647 trayek / rute. Dengan syarat tersebut jelas, masyarakat perlu kendaraan untuk bertransportasi. Di mana persebarannya sendiri tidak dapat diakses dengan jumlah tertentu hanya bisa diakses dengan kendaraan pribadi dan sebagian besar hanya bisa diakses oleh kendaraan roda dua. Berdasarkan pemaparan di atas, prospek bisnis / pemasaran kendaraan roda dua di Kabupaten Subang sangat menjanjikan. Tentu harus didukung dengan pemasaran yang baik, disetujui memilih daerah-daerah dengan analisis klasterisasi daerah persebaran kendaraan umum. Untuk kemudian dijadikan sasaran pemasaran kendaraan roda dua. Penerapan teknik Penambangan data Metode pengelompokan menggunakan Algoritma K-Means Pengelompokan pada data KOPJAS Kabupaten Subang dari 26 Kecamatan untuk melakukan klasterisasi persebaran Trayek di Kabupaten Subang sebagai bahan promosi pemasaran kendaraan roda dua. Diperoleh data yang ditabulasi, dilakukan pemilihan 2 centroid secara acak, untuk mendapatkan dua klaster. Selanjutnya menghitung besaran rasionya. Kemudian dilakukan pencarian nilai jarak baru ke centroid baru, penghitungan jarak berhenti kompilasi nilai rasio tidak berubah lagi, tentukan jarak minimum dan kuadrat jarak minimum, Jadi didapat 4 kali iterasi. Bagaimana K-berarti Clustering mampu melakukan klasterisasi Keamatan di Kabupaten Subang. Aplikasi yang digunakan dalam mengolah data tersebut yaitu Xampp, Php, MySql dan Notepad ++.
IMPLEMENTASI METODE WEIGHTED PRODUCT DALAM MEMONITOR GUDANG PENYIMPANAN ROTI BERBASIS INTERNET OF THING PADA PLATFORM NODE-RED
Authors: Wijaya Anderias Eko , Nurjaman Haris
Published: September 2020

Metode Weighted Product (WP) merupakan salah satu metode yang dapat digunakan pada proses pengambilan keputusan untuk menentukan kandidat terbaik. Pada penelitian ini Metode WP digunakan untuk menentukan penyimpanan gudang roti untuk Roti Kuro Subang.Roti Kuro Subang merupakan salah satu unit usaha yang saat ini bergerak dibidang pengolahan produk makanan roti. Melalui pengembangan unit usaha maka diperlukan sebuah gudang penyimpanan roti. Untuk membantu pihak Roti Kuro Subang menentukan gudang penyimpanan yang diperlukan sistem yang dapat digunakan gudang penyimpanan yang paling sesuai. Metode yang digunakan dalam pembuatan sistem ini adalah metode Weighted Product (WP). Metode ini dipilih karena mampu memberikan pilihan yang terbaik dari pilihan alternatif. Dengan memasukkannya konsep Internet of Things (IoT) pada penelitian kali ini dapat meningkatkan akurasi dalam menentukan nilai pada penilaian alternatif.Platform web yang digunakan adalah Node-red dan basis data yang digunakan adalah MySQL. Hasil dari penelitian ini adalah memberikan alternatif penyimpanan gudang yang paling sesuai untuk Roti Kuro Subang.
RANCANG BANGUN SISTEM PENGIDENTIFIKASI TRAVEL BAG PADA KELOMPOK BIRO PERJALANAN UMROH/HAJI BERBASIS WEB
Authors: Parlaungan S. Timbo Faritcan , Wisnu Dede
Published: September 2020

Perkembangan Teknologi Informasi salah satunya bergerak di bidang jasa Perjalanan Umrah. Salah satunya pencatatan yang dilakukan adalah proses pencatatan dan identifikasi terhadap kepemilikan tas peserta umrah atau haji. Pencatatan yang dilakukan secara manual atau diatas kertas akan menyulitkan proses identifikasi tas karena beresiko besar untuk rusak maupun hilang.
Sistem informasi berbasis web yang berjalan di jaringan computer diintegrasikan dengan perangkat keras mikrokontroler dapat dimanfatkan untuk pencatatan data dan identifikasi tas secara digital. Penggunaan system dengan metode digital akan mempermudah identifikasi tas. Yang akan menjadi lebih cepat dan data tersimpan secara aman.
Perancangan dan pembuatan system pengidentifikasian travel bag berbasis web menggunakan mikrokontroler adalah solusi untuk aplikasi pencatatan data dan identifikasi tas peserta dari biro perjalanan umroh atau haji. Dengan menggunakan system ini pihak biro perjalanan dan peserta akan merasa aman dan nyaman karena resiko tas tertukar sangat minim. Selain itu seluruh data tas dan pemiliknya tersimpan secara digital dan bisa diakses.
IMPLEMENTASI METODE FUZZY TAHANI DALAM MENENTUKAN REKOMENDASI PEMBELIAN LAPTOP (Studi kasus di Toko Mega Alvindo Kalijati Subang)
Authors: Murdianingsih Yuli , Isbahatunnisa Isti
Published: September 2020

Konsumen laptop dimungkinkan berasal dari berbagai kalangan masyarakat. Pastinya ada yang awam da nada juga yang dari kalaangan mengerti seperti latar belakang pendidikan IT dan sebagainya.untuk membantu memberikan rekomendasi dalam pembelian laptop, khususnya dengan variable type laptop, lebar layar monitor, harga, kapasitas memory dan kapasistas hardisk maka diperlukan system pengambilan keputusan berbasios computer menggunakan metode fuzzy tahini. Studi kasus dilakukan di toko Mega Alvindo Kecamatan Kalijati Kabupaten Subang.dipilih 10 record data laptop dan dilakukan pembuatan fungsi keanggotaan untuk variable type laptop, lebar layar monitor, harga, kapasitas memory dan kapasistas hardisk. Setelah diperoleh derajat keanggotaan untuk setiap variable. System rekomendasi selanjutnay direalisasikan dengan merancang dan implementasi basis data, meracang dan implementasi antar muka berbasis web. Dapat diimplementasikan system pemberi rekomendasi pembelian laptop menggunakan metode Fuzzy Tahani dengan variable type laptop, lebar layar monitor, harga, kapasitas memory dan kapasistas hardisk.
Kata kunci: Laptop, Fuzzy Tahani, rekomendasi.
Upaya Meningkatkan Angka Kunjungan Museum Melalui Social Media Marketing – Studi Pendahuluan
Authors: Cornellia Ayu Helena , Hermawan Hary
Published: September 2020

Digital marketing, termasuk social media marketing, memegang peran penting dalam memaparkan banyak hal. Museum di Yogyakarta sudah banyak melakukan promosi melalui media sosial dan mengikuti tren, antara lain Museum Sonobudoyo dan Museum Sandi. Berbagai tantangan ditemui dalam mengembangkan media sosial di museum, misalnya kondisi nyata museum yang belum dapat melakukan banyak inovasi dan regulasi yang mendasari. Kedua museum (Museum Sonobudoyo milik Pemerintah Daerah Yogyakarta dan Museum Sandi adalah milik Badan Sandi Negara Jakarta) dipilih berdasarkan purposive random sampling, yaitu berdasarkan keaktifan dalam update media sosial selama 6 bulan terakhir terhitung dari Oktober 2019 – Maret 2020. Studi kualitatif dan kuantitatif diadakan untuk menilai persepsi dan opini masyarakat terhadap museum serta mencari tahu apa yang sebaiknya ditingkatkan oleh pihak museum sehingga masyarakat semakin tergerak untuk datang ke museum. Hasil studi ini diharapkan akan menjadi panduan museum untuk memperbaiki diri dan beradaptasi dengan situasi dan trend wisata yang ada di masyarakat berdasarkan disrupsi teknologi yang ada saat ini.
Analisis Medan Kekuatan Terhadap Barapan Kebo Sebagai Atraksi Community Based Tourism (CBT) di Kabupaten Sumbawa Barat
Authors: Ma'ruf Amir
Published: September 2020

Pariwisata berbasis masyarakat atau Community Based Tourism (CBT) merupakan konsep pengelolaan pariwisata yang menjanjikan manfaat maksimal bagi masyarakat, menjadikan pariwisata inklusif bagi masyarakat, dan lebih menjamin keberlanjutan pariwisata sendiri.

Atraksi wisata yang paling mungkin dikelola ala CBT adalah wisata budaya yang memiliki banyak atraksi yang digemari para wisatawan saat ini. Dalam pada itu, Barapan kebo merupakan permainan rakyat yang secara rutin diselenggarakan oleh masyarakat di Pulau Sumbawa. Kajian ini bertujuan untuk mengidentifikasi kesesuaian barapan kebo untuk dijadikan daya tarik wisata berbasis masyarakat dan menganalisis langkah strategis apa yang perlu dilakukan untuk menjadikan barapan kebo sebagai daya tarik wisata berbasis masyarakat. Alat yang digunakan adalah AMK. Hasilnya menunjukkan bahwa Barapan Kebo layak dijadikan daya tarik wisata berbasis masyarakat dan Faktor Kunci Keberhasilan (FKK) pendorongnya adalah kecenderungan wisatawana terhadap budaya yang unik dan FKK penghambatnya adalah belum dipasarkannya Barapan Kebo sebagai daya tarik wisata. Opsi langkah strategis terbaik yang harus segera dilakukan adalah memadukan atara penguatan FKK pendorong dan pelemahan FKK penghambat. Yaitu mempromosikan Barapan Kebo ke pasar pariwisata.
Exploring the Impact of Nature-Based Intervention on the Physiology, Emotions, and Ability to Self-Regulate in At-Risk Preadolescent Youth
Authors: McQuay Christine , Olmstead Charlea , Reamy Taylor , Richardson Elizabeth , Koslow Robert
Published: September 2020

Date Presented 03/26/20

The purpose of this study was to examine the impact of nature-based interventions on physiological and emotional responses in at-risk preadolescent youth. Preliminary results indicate a decrease in resting heart rate and an increase in positive emotional states following the interventions. Inclusion of nature-based activities in OT interventions for at-risk youth can contribute to advancements in occupational justice and engagement for this population.

Primary Author and Speaker: Christine McQuay

Additional Authors and Speakers: Charlea Olmstead, Taylor Reamy

Contributing Authors: Elizabeth Richardson, Robert Koslow
Screenwriting is Rewriting
Authors: Epps Jack
Published: September 2020

If there is one skill that separates the professional screenwriter from the amateur, it is a writer's ability to rewrite successfully. Even for the most battle-hardened screenwriter, rewriting can be confusing and difficult. Notes are often contradictory, the solutions are not always clear, and when deep in the middle of a rewrite, it's hard to have distance and perspective.

From Jack Epps, Jr., the screenwriter of Top Gun, Dick Tracy and The Secret of My Success, comes a comprehensive guide that explores the art and craft of rewriting. Using a method he developed over years of working as a professional writer and script doctor, Epps guides the writer from First Draft to Final Polish through a series of focused passes which target specific rewriting challenges.

With Screenwriting is Rewriting, you will find tips on organizing notes, creating a game plan, and executing a series of precision focused passes that address the major story, character and plot issues. Chapters cover: Interpreting Notes, The Foundation Pass, Character Pass, Story & Theme Pass, Structure Pass, and Polish Pass. Studio notes, game plans and beat sheets from his own work on Sister Act and Top Gun are included, along with exclusive interviews about rewriting with screenwriting masters Robert Towne (Chinatown), Frank Pierson (Dog Day Afternoon), and Susannah Grant (Erin Brockovich). Screenwriting is Rewriting takes the mystery out of rewriting and helps the writer build a professional screenplay, one layer at a time.
Spectroscopic Imaging of Sub-Kilometer Spatial Structure in Lower Tropospheric Water Vapor
Authors: Thompson David R. , Kahn Brian H. , Brodrick Philip G. , Lebsock Matthew D. , Richardson Mark , Green Robert O.
Published: September 2020

Abstract. Understanding the subgrid spatial variability of water vapor is important for parameterizing and simulating cloud processes in General Circulation Models (GCMs). This study maps sub-kilometer spatial structures in total atmospheric column water vapor with Visible to Shortwave Infrared (VSWIR) imaging spectroscopy. We describe our inversion approach and validate its accuracy with coincident measurements by airborne imaging spectrometers and the AERONET ground-based observation network. Next, data from NASA’s AVIRIS-NG spectrometer enables the highest resolution measurement to date of water vapor’s spatial variability and scaling properties. We find second order structure function scaling exponents consistent with prior studies of convective atmospheres. Finally, we conclude by discussing the implications of these measurements and paths toward future campaigns to build upon these results.
Comparison of the U37K′, LDI, TEX86H, and RI-OH temperature proxies in sediments from the northern shelf of the South China Sea
Authors: Wei Bingbing , Jia Guodong , Hefter Jens , Kang Manyu , Park Eunmi , Wang Shizhu , Mollenhauer Gesine
Published: September 2020

Abstract. The temperature proxies
U37K′, LDI,
TEX86H, and RI-OH are derived from
lipid biomarkers, namely long-chain alkenones from coccolithophorids and
long-chain diols ascribed tentatively to eustigmatophytes, as well as
glycerol dialkyl glycerol tetraethers (GDGTs) and OH-GDGTs produced by
Archaea. The applicability of these proxies in the South China
Sea (SCS) has been investigated previously. However, in each study only one
or two of the proxies were compared, and the recently updated
calibrations or new calibrating methods such as BAYSPAR and BAYSPLINE were
not applied. Here, we investigate four proxies in parallel in a set of
surface sediment samples from the northern SCS shelf and relate them to
local sea surface temperature (SST), which allows for us to compare and assess
similarities and differences between them and also help improve regional
multiproxy seawater temperature reconstructions. Our results indicate that
U37K′ reflects annual mean SST with a
slight bias toward the warm season. Terrestrial inputs appear to have a
significant impact on LDI, TEX86H, and
RI-OH proxies near the coast, leading to colder LDI- and
TEX86H-derived temperatures but a
warmer RI-OH temperature estimate. After excluding samples influenced by
terrestrial materials, we find that LDI-derived temperature agrees well with
annual SST, while TEX86H- and RI-OH-derived temperature estimates are close to SSTs in seasons dominated by the
East Asian winter monsoon and summer monsoon, respectively. The different
seasonal biases of these temperature proxies provide valuable tools to
reconstruct regional SSTs under different monsoonal conditions.
Deep-learning based climate downscaling using the super-resolution method: a case study over the western US
Authors: Huang Xingying
Published: September 2020

Abstract. Demand for high-resolution climate information is growing rapidly to fulfill the needs of both scientists and stakeholders. However, deriving high-quality fine-resolution information is still challenging due to either the complexity of a dynamical climate model or the uncertainty of an empirical statistical model. In this work, a new downscaling framework is developed using the deep-learning based super-resolution method to generate very high-resolution output from coarse-resolution input. The modeling framework has been trained, tested, and validated for generating high-resolution (here, 4 km) climate data focusing on temperature and precipitation at daily scale from the year 1981 to 2010. This newly designed downscaling framework is composed of multiple convolutional layers involving batch normalization, rectification-linear unit, and skip connection strategies, with different loss functions explored. The overall logic for this modeling framework is to learn optimal parameters from the training data for later-on prediction applications. This new method and framework is found to largely reduce the time and computation cost (~ 23 milliseconds for one-day inference) for climate downscaling compared to current downscaling strategies. The strength and limitation of this deep-learning based downscaling have been investigated and evaluated using both fine-scale gridded observations and dynamical downscaling data from regional climate models. The performance of this deep-learning framework is found to be competitive in either generating the spatial details or maintaining the temporal evolutions at a very fine grid-scale. It is promising that this deep-learning based downscaling method can be a powerful and effective way to retrieve fine-scale climate information from other coarse-resolution climate data. When seeking an efficient and affordable way for intensive climate downscaling, an optimized convolution neural network framework like the one explored here could be an alternative option and applied to a broad relevant application.