bluuebunny/crossref_metadata_2025 huggingface dataset:
Voice broadcast based on 5G sensor in urban fire emergency system application
Authors: Huang Ying , Dong Gang , Liu Zhangyin , Zhu Jiong , Peng Weidong
Published: January 2023

With the rapid development of 5G sensors, the development of low cost, low power consumption, and miniaturization is also constantly progressing, and 5G sensor networks have achieved great development. Node positioning technology is an important support for 5G sensors, so it has been a hot research direction in recent years. This article has carried on the basic discussion to the speech broadcasting technology, and introduced the speech broadcasting coding in many aspects, including the development history, the current situation and the compression coding algorithm. This article has launched a basic analysis and discussion on the voice broadcast algorithm, such as its basic principles and classification. In order to minimize the property losses and casualties caused by urban fires and improve the efficiency and success rate of urban fire emergency systems, it is necessary to be able to query fire information in a timely and effective manner and formulate emergency protection. As we all know, China’s current economic development is in a period of steady improvement, and the process of urbanization is gradually accelerating, especially the number of high-rise and super high-rise buildings has increased significantly. Therefore, once a city fire occurs, it will not only cause huge losses of property, but also may cause a large number of casualties. Although the current fire protection system in Chinese cities is relatively complete, there are still some problems that have not been resolved in actual work, such as insufficient technical equipment and insufficient response speed in some areas due to economic constraints. Therefore, it is very necessary to establish an efficient urban fire emergency information system, not only to be able to query fire information in a timely and effective manner, but also to be able to formulate emergency support plans for specific actual situations.
Optimal operation strategy of wind-hydrogen integrated energy system based on NSGA-II algorithm
Authors: Sun Teng , Wang Weidong , Wen Xuan
Published: January 2023

In order to improve the economy of the multi energy system and the efficiency of energy utilization, the research adopts the non dominated sorting genetic algorithms II (NSGA-II) to expand the population space. The elite strategy is introduced to improve the intelligent algorithm, and then the diversity of the population is retained to improve the optimization accuracy of the algorithm. In addition, the adaptive operator is introduced to improve the NSGA-II algorithm to improve the global search efficiency. The performance test of fast non dominated sorting genetic algorithm shows that the improved algorithm using elite strategy has better performance in coverage index, diversity index and convergence index. For example, in terms of convergence index, the improved NSGA-II algorithm has improved 0.0159, 0.822, 0.0243 and 0.0171 in four ZDT test functions. On the energy optimization operation for the integration of wind and hydrogen, the improved NSGA-II algorithm has obtained lower cost, with a total configuration cost of 606 million yuan, while the total system configuration cost corresponding to the unimproved NSGA-II algorithm is 624 million yuan, so the total system cost after the algorithm improvement has decreased by 18 million yuan. Therefore, this method has a better economy and higher energy efficiency.
Multi-objective intelligent algorithm model design for housing environment optimization
Authors: Xu Yuanyuan
Published: January 2023

With the improvement of the national living standard, the buyers have higher and higher requirements for the rationality and aesthetics of the spatial planning and layout of the residential area. The traditional residential space planning method is purely manual design, which is inefficient, and the design effect will be greatly affected by the designer’s work experience and personal aesthetics. Therefore, this research attempts to combine Pareto solution set and piecewise prediction idea into genetic algorithm, propose an algorithm for solving multi-objective optimization problems, and build an intelligent housing environment planning system based on this. The statistical results of simulation experiments show that the system can output more design schemes with better overall quality than the comparison system and manual planning results, and the stability of multiple operations is higher. When the number of iterations reaches 200, the average value of Pareto optimal solution number and optimal solution quality index QPS of the former is 44 and 0.41, respectively. The expert group analyzed the design results of this method and the manual method for an actual case, and found that the results designed by this method met the requirements and the calculation efficiency was much faster than manual processing. From the simulation test data and the actual case analysis, it can be seen that the intelligent housing environment planning system designed in this study is helpful to improve the efficiency of residential space design and the stability of residential space scheme style.
Determination of comprehension levels of prospective chemistry teachers related to covalent bonding by using concept cartoons strategy
Authors: Şen Şenol , Temel Senar , Özcan Özgür
Published: January 2023

This study aims to identify prospective chemistry teachers’ difficulties in comprehension of the subject of polar and nonpolar covalent bonding. In addition to that, attempts were also made to determine how they interpreted the nature of force in covalent bonding. The study was conducted in a qualitative research method. Three different concept cartoons were used for data collection. 15 prospective chemistry teachers were included in the study. All of the participants were chosen through a purposeful sampling method. The data collected were put to content analysis, consistent with the nature of qualitative research studies. Following the analyses, the prospective chemistry teachers’ levels of comprehension of the subject were revealed and the issue was discussed.
TUHAN, IZINKAN AKU BERNYANYI: ROCKER MUSLIMAH SUNDA DAN RESISTENSI TERHADAP STEREOTYPE
Authors: Noorbani Muhammad Agus , Nur Mahmudah
Published: February 2023

This paper provides an analysis of resistance carried out by a rock band called Voice of Baceprot (VoB). VoB is a group of heavy metal musicians consisting of three young Sundanese Muslimah from Garut, Indonesia. Sundanese women are usually portrayed as having ambiguous characteristics, especially as depicted in the media. Physically, they are often perceived as attractive and ageless, while their personality traits are considered hard-working, assertive, principled, smart, and trustworthy. These perceptions thus create a negative stereotype of Sundanese women, especially since it is still taboo for muslim women to do rock music. This article aims to explain how these young Sundanese muslimah resist and negotiate their freedom as expressed through heavy metal music. Content analysis is used to analyze the data, such as the interview and the lyrics of their songs. The result shows that the values of religion still prevent women, especially young women, to pursue a career in arts. How VoB fight for freedom is not driven in a frontal and disruptive way, but they use their own vulnerability as their resistance.  Through the lyrics, the way they dress, and how they express themself in the media, these young women show that freedom will never oppose from being shari’a muslim.
Interpretation of Isolated Magnetic Profile Using Simulated Annealing Approach
Authors: Shinu Sunaina , Dubey Chandra Prakash
Published: January 2023

Understanding the magnetic anomaly in terms of the subsurface causative source plays a pivotal role in mineral exploration as well as in other geological applications. Automatic modeling of such isolated profile data is still rising, and fundamental improvements are needed in analyzing the association of subsurface rocks with the magnetic anomaly in terms of various independent model parameters. Here, we propose a MATLAB-based simulated annealing algorithm to simplify the interpretation process of magnetic anomalies. The performance of the adopted approach over various synthetic models of simple geometries like spheres, dikes, sills, and prisms is analyzed with and without contaminated noise. These geometries are widely used for some specific types of ore bodies such as iron, base metals, and mineralization such as skarns, massive sulfides, etc. Finally, two different real deposits of Chromite Ore and Uranium Ore are taken along with their magnetic anomalies to interpret their subsurface geometries in terms of model parameters. The estimated structures are verified to have a great affinity with the structures obtained in previously published works of literature. Furthermore, the present computational algorithm provides a user-friendly approach without any computational difficulties with minimum cost.
Test results of new semi-lamb tomato varieties in the conditions of the Terek-Sulak lowland of the Republic of Dagestan
Authors: Akhmedova Patimat
Published: February 2023

Abstract. The purpose of the research is to study the collection and breeding material of tomatoes with a determinant bush type in open ground conditions, and to identify the best samples based on the results of the research on economically valuable traits for their further use in tomato breeding. Scientific novelty. Recent events in the country show the need to study and recommend domestic tomato varieties and hybrids in safe and risky farming zones. The article presents a brief description of new domestic tomato varieties with a short growing season. Samples of morphological and biometric indicators for the source material of tomato breeding were selected. Varieties with short interphase periods “shoots –flowering”, “flowering – ripening” were identified. On the basis of a comprehensive assessment of early maturity, economically valuable characteristics and tasting evaluation of fruits, promising varieties were noted for recommendation and implementation in the production of the lowland and foothill parts of Dagestan. Methods. Field and laboratory. The method for the study was 8 new semi-stamp cultivars of VNIISSOK selection. Descriptions of tomato plants were carried out taking into account morphological (stem height, number of shoots, number of leaves, number of brushes, number of ovaries and fruits), agrochemical and complex of economically valuable characteristics (total and early yield, marketability of fruits, fruit weight, dry matter, sugar, fruit tasting evaluation). Results. According to the maturation dates, the samples were divided into three groups: very early – Severyanka, Blagodatnyy, Magnat, Voskhod VNIISSOKa (97–100 days); early – Patris, Viking, Perst (102–105 days); middle-early – Sodruzhestvo, Fakel (111–114 days). According to the type of bush, we have identified 5 ordinary and semi-lamb samples with a height of no more than 78 cm. Two samples had a height of 50.53 cm (Patris, Perst) and an average fetal weight of 72 and 60 g. Three samples had a height of 70, 71, 72 cm (Voskhod VNIISSOKa, Blagodatnyy, Sodruzhestvo) and an average fetal weight of 107, 110, 130 g respectively. According to the output of gross output, the best indicators were of the following varieties: Blagodatnyy – 86.3 t/ha, Voskhod VNIISSOKa – 82.7 t/ha, Sodruzhestvo – 77.6 t/ha, Patris – 68.2 t/ha. The following grades had a high yield of marketable products: Voskhod VNIISSOKa, Patris – 92 %, Blagodatnyy – 91 %, Perst – 90 %.
The problem of “social exclusion” and the efficiency of food consumption: theoretical and methodological aspects
Authors: Voronin Boris , Voronina Yana , Stozhko Dmitriy , Stozhko Konstantin
Published: February 2023

Abstract. In the context of a steadily changing macroeconomic and geopolitical situation and the formation of a new social reality, the issues of the efficiency of food supply and consumption are coming to the fore in the policy of any state. In this regard, the object of this study is to analyze and evaluate the phenomenon of social exclusion in food consumption and its role in the development of the food supply system for the population of our country in the context of macroeconomic instability and turbulence. The objectives of the study are: to identify the most important reasons that cause the persistence of the phenomenon of social exclusion in the field of food consumption in modern Russian society; assessment of the main factors and possible consequences of social exclusion in the socio-economic development of the country; analysis of the relationship between social exclusion, the efficiency of food consumption and the level of poverty in the sphere of food consumption of the population. Methods. To achieve the goal, inductive-deductive, program-target, structural-functional, expert-analytical and historical-retrospective methods were used. Scientific novelty consists in revealing the fundamental causes and main factors of maintaining social exclusion in the sphere of food consumption and determining ways to overcome it in the new social reality. Among the causes of social exclusion in the field of food consumption are endogenous and exogenous factors: the rudimentary preservation of the remnants of the past nomenclature system of catering and its revival in the face of growing bureaucracy; a relatively low share of imported high-quality food products and a high share of low-quality domestic food products; low level of transparency in the organization of food supply; weak legal control and a high level of irresponsibility of officials in the organization of various (especially special) food practices; comparatively high rates of inflation and growth in food prices compared to other groups of goods. The practical significance of the study lies in the development of theoretical and methodological aspects of this problem and the possibilities of its application in the food policy of the state.
Hubungan persepsi pasangan usia subur (PUS) berkebutuhan khusus dengan pelayanan antenatal pada komunitas umbrella disability project kota Bukittinggi
Authors: Andriani Liza , Andri Rantih Fadhlya , Zalukhu Aze Renata Fenzelina
Published: January 2023

Berdasarkan Undang-Undang Nomor 19 Tahun 2011 tentang Pengesahan Konvensi Hak-Hak Penyandang Disabilitas khusunya Pasal 25 bahwa mereka mempunyai hak untuk mendapatkan jaminan kesehatan. Ketidakmampuan perempuan disabilitas untuk menjadi seorang ibu, menyebabkan mereka enggan untuk melakukan kunjungan antenatal.Selain itu faktor komunikasi ketika memberikan pendidikan kesehatan tentang kehamilan menjadikan pelayanan antenatal tidak berkualitas sehingga mereka  mempunyai persepsi dan tingkat kepuasan yang kurang baik terhadap pelayanan kebidanan. Penelitian ini bertujuan untuk mengetahui hubungan  persepsi PUS Berkebutuhan Khusus dengan Pelayanan Antenatal pada Komunitas Umbrella Disability Project Kota Bukittinggi. Jenis penelitian bersifat deskriptif kuantitatif. Populasi adalah seluruh PUS yang berada di komunitas disabilitas sebanyak 12 orang dan pengambilan sample dilakukan secara total sampling. Pengumpulan data dilakukan pada bulan Agustus 2022 dengan teknik wawancara menggunakan kuesioner dan observasi. Saat melakukan wawancara, peneliti didampingi oleh pengurus komunitas UDP sebagai translator. Hasil penelitian didapatkan bahwa lebih dari setengah (58.3 %) responden memiliki tingkat pendidikan tamat SMA, lebih dari setengah (66.7%) memperoleh pelayanan antenatal care, dan lebih dari setengah (58.7%) mempunyai persepsi yang baik tentang pelayanan Antenatal Care. setelah dilakukan uji analitik Chi-Square didapatkan bahwa ada hubungan bermakna antara persepsi PUS berkebutuhan khusus dengan pelayanan antenatal di komunitas UDP Kota Bukittinggi (p value 0,05). Berdasarkan asumsi peneliti, faktor komunikasi yang informatif paling berpengaruh dalam memberikan kepuasan dan persepsi yang baik terhadap pelayanan kehamilan pada perempuan difable yaitu dengan didampingi oleh keluarga atau suami.
Analisa Simpang Tak Bersinyal (Studi Kasus Di Ruas Jalan Taman Simpang Kandis Kota Bengkulu)
Authors: S Rima , Agustomi Endri , Pujiastutie Elly Tri
Published: February 2023

Intersection are knots in transportation network where two or more roads meet, in this area conflict is occurred, law of traffic are applied to handle this conflict to make sure who gets the priority to use the intersection first. Control Intersection make use of maximum capacity of the intersection, reducing and preventing accidents by reducing the number of conflicts. This research intend to analyse the traffic and calculate traffic flow at Taman Simpang Kandis road. To get data for this research purpose can get done by using direct observation, and count number of vehicle that passed the four arms intersection and three arms intersection. The result of this survey categorized by light vehicle, heavy vehicle, motorcycle, and non-motorized vehicle. Four arms intersection performance analysed by observe capacity, saturation degree, delay, queue chance is still below the standard based on MKIJI 1997. The best alternative for the four arms intersection are by combining installation the “prohibited to stop“ road sign and change 2 lanes with 2 directions to four arms intersection with 2 lanes and 1 direction. Three arms intersection performance analysed by observe capacity, saturation degree, delay, queue chance is still below the standard based on MKIJI 1997. The best alternative for this three arms intersection are by prohibited to turn left from Rustandi Sugianto 1 road and prohibited to turn right form Rustandi Sugianto 2 road where can make vehicle stacked on side of that road.
Pemanfaatan Limbah Tutup Botol Air Mineral Sebagai Filler Pada Lapis Perkerasan Base a
Authors: Fajri Aswantu , Sazuatmo Sazuatmo
Published: February 2023

One of the most common plastic wastes found around us is the cap of mineral water bottles. The waste of mineral water bottle caps as a filler on the basis is expected to reduce the impact of plastic waste it self and reduce rock waste in the quarry. Tests carried out by adding fillers of mineral water bottle cap waste as much as 0%, 10%, 20%, and 30%. The ability of mineral water bottle cap waste as a filler can be tested by looking at the value of the California Bearing Ratio (CBR) generated after addition. CBR testing is carried out by the laboratory CBR test method using a CBR penetration tool. From the examiners, the results show that; base A aggregate without the addition of mineral water bottle cap waste with a CBR value of 93.38%; the addition of 10% of mineral water bottle cap waste resulted in a CBR value of 98.73%. The addition of 20% obtained a CBR value of 96.55%; and an addition of 30% resulted in a CBR value of 87.65%. The addition of 10% and 20% of mineral water bottle cap waste filler can increase the CBR base A value, because it produces a larger CBR value without addition. Meanwhile, an increase of 30% will actually reduce the strength of the base itself because the resulting CBR value is smaller. The addition of filler of mineral water bottle cap waste can increase the CBR value of base A with the right composition. Utilization of mineral water bottle cap waste at base A will reduce the amount of plastic waste and reduce environmental pollution, as well as reduce the overexploitation of rocks for base A raw material.
Pengaruh Penambahan Abu Tandan Kelapa Sawit Terhadap Daya Dukung Tanah Lempung
Authors: Fitramsya Sendi , Pujiastutie Elly Tri
Published: February 2023

ABSTRACT

One of the most important material that has great impat to a structure or onstrution in civil engineering job is soil, either that job is building or road pavement construction. One of problem which may happen faced by consultant or contractor ( especially for road pavement construction ) is take care of soil and other bad component to make sure those components can be used as ingredient for that pavement construction. Thing can be done to fix the mechanic property in this research is by using chemical way like adding oil palm ‘s stem ashes with 0%, 6,5%, 7%, 8%, and 8,5 % variation from clay. Biggest CBR value happen when 0,2 penetration with CBR value was 18,078% by using 8,5 % oil palm’s stem addictive. This value has increased by 2,288 % from the CBR value from the original soil which is 15,790%. With adding 6,5% oil palm’s stem ashes the CBR value increased 0,703%, when adding 7% increased by 0,273% and also when adding 8% increased 1,168%. This CBR value qualified Bina Marga 2018 general specification ( Third revision ) where CBR value > 6%.
From “Foreign Languages” to “World Languages” within U.S. Institutions: Abandoning Misleading Terminologies
Authors: Anderson Roger
Published: January 2023

This article unpacks “foreign” in “foreign language education”, demonstrating that the term marginalizes, misrepresents, and misleads the U.S. towards a less interculturally competent version of itself. Instead of foreign, “world languages” is better reflective of the country’s rich cultural diversity and linguistic landscape, while honoring -not othering- its multilingual inhabitants.
Redesigning Internationalisation with Beginner’s Mind
Authors: Unkule Kalyani
Published: January 2023

Higher education internationalisation carries immense potential to deliver to the cause of intercultural dialogue and understanding. To fulfil this potential, practitioners must consistently challenge mechanisms which reinforce the hierarchy of ways of knowing and being. The answer lies in cultivating beginner's mind rather than competing based on the paternalistic and homogenising ideal of best practice.
Learning Self Through Shosin in International Education
Authors: Jibiki Yuka
Published: January 2023

Shosin, the beginner’s mind is an idea of self-reflection. It reminds you to embrace the unknown and differences. It gives you an opportunity to re-learn yourself. This value is a key to guiding students who learn worlds and discover themselves through international education.
“You Don’t Build Bridges to Safe and Familiar Territories”: Study Abroad Practice Based in Reconciliation as Falling Apart
Authors: Unkule Kalyani
Published: January 2023

This three-part article series aims to relate a new understanding of reconciliation with higher education internationalization practice, particularly study abroad, drawing on Anzaldua’s (2002, p. 3) imagination of bridging as “the work of opening the gate to the stranger, within and without”. Part I discussed some of the challenges that reconciliation as a modality of transitional justice shares with higher education internationalisation. Prominent critiques of standard practices deployed to achieve post-conflict reconciliation point to the need for embracing in-between-ness as the liminal space between discord and harmony, rather than an effort to arrive at standardised narratives in service of moving on, while leaving unexamined the dominant paradigms and systems linked to conflict. Part II will draw out specific interventions that stem from positing reconciliation as in-betweenness and study abroad as building bridges back to ourselves.
Treating International Students Beyond Teaching Cultural Differences?
Authors: Peng Suhao
Published: January 2023

This critical voice essay draws attention to rethinking intercultural learning for international students. Teaching cultural differences is unsustainable but reinforces stereotypes.
Challenges and Opportunities in the International Higher Education “Post-Pandemic” Landscape
Authors: Arif Abu , Whatley Melissa
Published: January 2023

International education is a vast field of scholarship and practice. Internationalization of higher education (IHE) has been contested, debated, deconstructed, and reconstructed. While some have discussed the end of internationalization (Brandenburg & De Wit, 2011), others have discussed reimagining or rebuilding this field of practice (Stein, 2021). Since the post-World War II era, the international education sector has faced many challenges including the Cold War, 9/11 and its responses, the election of Donald Trump, and Brexit, but perhaps nothing compares to COVID-19. The pandemic has severely impacted the core of the internationalization of higher education – human mobility. CISN reached out to three IHE scholars and leading practitioners in the USA and Canada to learn about their visions for the future of IHE in the “post-pandemic” landscape. We encourage readers to send us their comments about their own responses to the following questions and their thoughts on the responses from Dr. Sonja Knutson, Dr. Harvey Charles, and Dr. Adel El Zaïm outlined here.
Higher Education Practitioners' Experience in a Global Pandemic
Authors: Laird Chelsey
Published: January 2023

I write this reflection from my perspective as an international education practitioner and administrator, but also as a doctoral student in the Faculty of Education at Simon Fraser University. The intersection of these identities presents a perspective that is informed by my lived reality of what internationalization of higher education is, in the Canadian context. It is this space, between theory and practice of internationalization of higher education, where my research interests lie. I am specifically focused on the experience of higher education staff members. This is of particular interest in the current context of the COVID-19 pandemic and its impact on the internationalization of higher education.
Theoretical Approaches to the Study of International Students
Authors: Hou Minghui , Yu Jing , Katsumoto Shinji
Published: January 2023

In current internationalization research, international students tend to be considered a homogeneous group, overgeneralized as ‘internationals’ (Lee, 2014). The ‘international student experience’ is assumed to apply to all international students, but there are nuances in international students’ experiences (Heng, 2019). Jones (2017) notes that international student experiences are influenced by their personal, familial, and institutional backgrounds. In our first essay on this topic, we introduced different methodological approaches to study international student diversity. In this second essay, we present some key theoretical approaches on which scholars can develop their study and methods to explore and analyze international students' diverse experiences in U.S. higher education.
Perancangan Aplikasi Android Untuk Memonitoring Salinitas dan Suhu Air Aquarium pada Budidaya Ikan Badut
Authors: Sahnah Malika , Rafsyam Yenniwarti
Published: February 2023

Ikan badut merupakan ikan yang banyak dibudayakan oleh petani pada aquarium. Dalam pembudidayaannya, terdapat beberapa parameter yang perlu diperhatikan, yaitu kadar salinitas air berkisar 29 PPT - 37 PPT dan suhu air beriksar 25°C-30°C. Untuk memudahkan dalam pemantauan salinitas dan suhu pada aquarium, maka dibuatlah Aplikasi NEMOKU untuk sistem monitoring dan kontrol jarak jauh salinitas dan suhu air melalui Aplikasi Android, yang terhubung dengan sistem pengontrol berupa heater aquarium, serta pompa air tawar dan air garam. Aplikasi NEMOKU memiliki sistem monitoring secara otomatis dan manual. Pada sistem manual, petani ikan mengakitfkan sistem memalui aplikasi, sesuai dengan kondisi pada aquarium. Apabila salinitas <29 PPT, petani mengaktifkan pompa air garam, jika nilai salinitas >37 PPT, mengaktifkan pompa air tawar dan apabila suhu <25°C, mengaktifkan heater aquarium. Pada sistem otomatis, sistem akan otomatis aktif untuk menjaga salinitas dan suhu pada aquarium. Dari pengujian yang dilakukan, sistem yang dirancang sudah bekerja baik dalam mengirimkan data salinitas dan suhu serta melakukan kontrol jarak jauh. Spesifikasi alat yang digunakan untuk aplikasi yang dibuat menggunakan software Android Studio Version Bumblebee,  laptop dengan processor Intel® Core TM i3 2370 M CPU @ 2.8 GHz, Memory 4 GB, Harddisk 500 GB dan Monitor 14 inches.
The Impact of Processing Methods and Conditions on Nutritional Properties of Soybean-Based Tofu: A Review
Authors: Anjum Sofiya , Agnihotri Vasudha , Rana Smita , Pandey Anita , Pande Veena
Published: January 2023

The soybean seed is used for the preparation of protein rich tofu. Along with protein, it is also rich in many other nutrients including carbohydrate, crude fibre, carbohydrate, fat, minerals, and isoflavones. Antinutrients are also present in tofu, although the concentration is less that the raw grains. The nutrient content is affected by the tofu preparation method used starting from selection of suitable soybean seed, seed soaking, sprouting, soymilk production and coagulation using different types of natural and artificial coagulants. These procedures also affect the textural properties of the tofu and their shelf life.
Real-time Detection of Cellular Metabolism: a New Trend for Intra-Operative Diagnosis of Cavity Margins
Authors: Abdolahad Mohammad , Kaviani Ahmad
Published: January 2023

Not applicable
СОЦІАЛЬНО-ПЕДАГОГІЧНИЙ СУПРОВІД ДІТЕЙ З ОСОБЛИВИМИ ПОТРЕБАМИ В ЗАКЛАДАХ ПОЗАШКІЛЬНОЇ ОСВІТИ
Authors: Сайко Н. О.
Published: February 2023

У статті обґрунтовується необхідність організації соціально-педагогічного супроводу дитини з особливими потребами в системі закладів позашкільної освіти. Конкретизуються поняття «соціально-педагогічний супровід», «індивідуальна програма соціалізації», «реабілітаційне середовище». Процес соціально-педагогічного супроводу представлений як взаємозв’язок у роботі соціального педагога, психолога, педагогів, дітей та їх батьків. Визначено основні завдання кожного напряму соціально-педагогічного супроводу. У роботі з батьками соціальний педагог, психолог акцентує увагу на характері ставленні батьків до дітей, аналізується конструктивний і деструктивний види ставлень. Підкреслюється, що особливе значення під час роботи з батьками має сформованість системи соціально значущих знань, приблизний перелік яких представлено за такими компонентами: соціально-психологічним, соці- ально-інтеграційним, соціально-правовим. У реалізації другого напряму соціально-педагогічного супроводу дитини з особливими потребами передбачено створення індивідуального реабілітаційного середовища, що розуміється нами, як сукупність суспільних, матеріальних та духовних умов, що забезпечують досягнення гармонії з навко- лишнім світом, становлення особистості як суб’єкта своєї життєдіяльності, переорієнтацію соціальних установок у результаті включення в нові позитивно орієнтовані відносини та види діяльності. Особливою умовою успішності соціалізації дитини нами виділено застосування методу опори на сильні сторони особистості (мрії, цілі, інтереси, уподобання тощо). Соціальний педагог, психолог має віднайти у кожної дитини такі сильні сторони і створити інди- відуальну програму соціалізації, яка містить систему заходів, що спрямовані на розвиток соціальних можливостей дитини та включає окремі види, форми, об’єми, терміни і порядок заходів, спрямованих на відновлення або вклю- чення особистості до соціального середовища. Третій напрям соціально-педагогічного супроводу передбачає орі- єнтацію педагогів на атракційне спілкування, на сприйняття кожної дитини у позитивному ореолі.
ШКІЛЬНА ДЕЗАДАПТАЦІЯ МОЛОДШИХ ШКОЛЯРІВ ЯК ПСИХОЛОГО-ПЕДАГОГІЧНА ПРОБЛЕМА
Authors: Мельничук С. Л.
Published: February 2023

У статті проаналізовано різні підходи науковців щодо дефініції поняття «шкільна дезадаптація». Зазначено, що несвоєчасне або помилкове діагностування причин і труднощів, які виникають під час навчання у школярів можуть призвести до складних проблем. Адже, своєчасне їх не вирішення у молодшому шкільному віці стає основою для різноманітних відхилень у психосоціальному розвитку на наступних етапах онтогенезу, з особливою гостротою виявляючись у підлітковому віці, коли ефективність корекційної допомоги знижується. Цим зумовлена актуальність дослідження. Проведено аналіз основних варіантів шкільної дезадаптації. Проаналізовано основні форми прояву дезадаптації так як: несформованість елементів і навичок навчальної діяльності; мотивації учіння, спрямованості; нездатність до довільної регуляції поведінки, уваги, навчальної діяльності. Визначено головні причини та наслідки шкільної дезадаптації. Зроблено висновок про те, що процес дезадаптації школярів до навчальної діяльності детермінується як зовнішніми, так і внутрішніми чинниками. У статті зазначається, що розглядаючи причини дезадаптації школярів необхідно комплексно підходити до питання порушення особистісного розвитку, а також зважати на психолого-педагогічні, соціальні чинники, які вливають на її прояв. І тільки тоді можна подолати шкільну дезадаптацію як проблему, яка ще і досі не повністю досліджена. Обгрунтовано припущення про те, що більшість із них можна позбутися завдяки тісній співпраці вчителів і батьків, а також шкільного психолога. Дезадаптацію молодших школярів можливо подолати використовуючи оптимальні умови навчального процесу і відповідні корекційні заходи.
Owner Specific Factors, Firm Specific Factors, Internationalisation and Performance of SMEs in Sri Lanka: A Conceptual Framework
Authors: Mudalige Dharshana , Ismail Noor Azizi , Dassanayaka Sarath
Published: January 2023

As SMEs are internationalising at a faster rate today, theories that can explain SME internationalisation and performance are of extreme importance. At present there is no agreement among scholars on a single theoretical framework on SME internationalisation and performance. The literature suggested that contemporary firm performance is not associated with traditional factors. However, firm internationalisation and SME performance seem to be directly associated with unobservable owner and firm factors. However the literature indicated that past research does not conclusively prove the complex impact of owner or firm specific factors on SME internationalisation and performance. To fill this research gap, a conceptual framework that explains the relationship between internationalisation and performance was developed based on internationalisation, entrepreneurship, and organisational learning theories. Owner specific factors and firm specific factors in the conceptual framework are brand orientation, entrepreneurial orientation, and industry context respectively. In addition, this framework expands the scope of study in internationalisation-performance relationship by considering the moderating effect of organisational learning. Five hypotheses were developed to test the relationship between the variables in the conceptual framework. The outcome of this research can enhance the understanding of SME internationalisation process and provide some insights for policy makers, and SME owners and managers.
Halal Governance in Malaysia
Authors: Matulidi Nornadia , Jaafar Harlina Suzana , Bakar Ahmad Naqiyuddin
Published: January 2023

Malaysia is in a strategic location in the South East Asia for the halal Industry, witha predominant Muslim population. The halal certificate by the Department of IslamicDevelopment (JAKIM) is recognized globally. The halal hub is confined within theparameters of governance support and cooperation, such as political will to improvein terms of public service, governance structure, policy and all related to systematicgovernance. This study discusses the halal governance issue and the halal governancein Malaysia. Data was collected through series of focus groups interviews whichmakes this study exploratory in nature. The study applies purposive sampling, asinformation is conveniently available from specific target groups. The paper shall servea reference for the government halal authority, higher institutions and researcherstoward development of halal industry in Malaysia and focussing on halal supply chainactivities which involves ministry, department and agency roles.
Attitude toward Conflict and Family Business Succession
Authors: Salim Linda , Mohd. Shariff Mohd. Noor , Ahmad Arshad Darwina
Published: January 2023

Conflict is central in family business. Family business consists of family membersworking together, using family and business logics. Efforts are done to mitigate theimpact of role conflicts. Nevertheless, conflict remains the top reason for discontinuity.Findings suggested that participants with positive attitude toward conflict take morerelaxed approach toward succession, with larger next generation talent pool. Thisgroup is egalitarian in strategic decision making and characteristically optimistic.Participants with negative attitude have a smaller talent pool for succession, since theyreserve leadership for the select few. They are more cautious, requiring successors toimplement their visions beforehand, and are less optimistic. This study contributes tothe body of knowledge and family business practitioners. Firstly, this paper introducesthe use of attitude toward conflict to predict behaviour during succession. Secondly,this paper inspires leaders to assess their attitudes, and if required to change theirattitudes, so that they can plan their succession accordingly.
The Energy-Economic Growth Nexus in Indonesia
Authors: Nugraha Andhyka Tyaz , Osman Nor Hasni
Published: January 2023

The aim of this study is to investigate the causal relationship between final energy consumption and economic growth for three main development sectors in Indonesia. In this study, we consider final energy consumption as energy indicator and the value added of development sectors as economic indicator. We use annual data from 1971 to 2014 and collected data from international energy agency and the world development indicator. We use Autoregressive distributed lag (ARDL) technique for cointegration and granger causality approach to explore direction of causality between the variables. We found a bidirectional relationship between energy and economic growth in the industrial sector in the long-run and in services sector in the short-run. Furthermore, we found a unidirectional relationship from economic growth to energy consumption in the services sector in the long-term and in the agriculture sector in the short and long terms. Based on these results, we concluded that economic growth is significantly influenced by final energy consumption on three development sectors in Indonesia, especially in the long-term. However, this study only focus on exploring energy-economic growth nexus on three development sectors in Indonesia and provide specific information for the policy makers on the three sectors in Indonesia. This study provides a new approach in terms of exploring energy-economic growth nexus in a single country and assess that energy-economic growth nexus in a single country should consider situations and conditions in each development sector.
The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic
Authors: Bone Leslie N. , Dayam Roya Monica , Lee Minhyoung , Kono Nozomu , Fairn Gregory D. , Arai Hiroyuki , Botelho Roberto , N. Antonescu Costin
Published: January 2023

Phosphoinositides (PIPs) are key regulators of membrane traffic and signaling. The interconversion of PIPs by lipid kinases and phosphatases regulates their functionality. Phosphatidylinositol (PI) and PIPs have a unique enrichment of 1-stearoyl-2-arachidonyl acyl species; however, the regulation and function of this specific acyl profile remains poorly understood. We examined the role of the PI acyltransferase LYCAT in control of PIPs and PIP-dependent membrane traffic. LYCAT silencing selectively perturbed the levels and localization of phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] and phosphatidylinositol-3-phosphate and the membrane traffic dependent on these specific PIPs but was without effect on phosphatidylinositol-4-phosphate or biosynthetic membrane traffic. The acyl profile of PI(4,5)P2 was selectively altered in LYCAT-deficient cells, whereas LYCAT localized with phosphatidylinositol synthase. We propose that LYCAT remodels the acyl chains of PI, which is then channeled into PI(4,5)P2 Our observations suggest that the PIP acyl chain profile may exert broad control of cell physiology.
Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase
Authors: Botelho Roberto , Efe Jem A. , Teis David , Emr Scott D.
Published: January 2023

 

Phosphatidylinositol-3,5-bisphosphate [PtdIns(3,5)P(2)] regulates several vacuolar functions, including acidification, morphology, and membrane traffic. The lipid kinase Fab1 converts phosphatidylinositol-3-phosphate [PtdIns(3)P] to PtdIns(3,5)P(2). PtdIns(3,5)P(2) levels are controlled by the adaptor-like protein Vac14 and the Fig4 PtdIns(3,5)P(2)-specific 5-phosphatase. Interestingly, Vac14 and Fig4 serve a dual function: they are both implicated in the synthesis and turnover of PtdIns(3,5)P(2) by an unknown mechanism. We now show that Fab1, through its chaperonin-like domain, binds to Vac14 and Fig4 and forms a vacuole-associated signaling complex. The Fab1 complex is tethered to the vacuole via an interaction between the FYVE domain in Fab1 and PtdIns(3)P on the vacuole. Moreover, Vac14 and Fig4 bind to each other directly and are mutually dependent for interaction with the Fab1 kinase. Our observations identify a protein complex that incorporates the antagonizing Fab1 lipid kinase and Fig4 lipid phosphatase into a common functional unit. We propose a model explaining the dual roles of Vac14 and Fig4 in the synthesis and turnover of PtdIns(3,5)P(2).

 
Selective regulation of clathrin-mediated epidermal growth factor receptor signaling and endocytosis by phospholipase C and calcium
Authors: Santos Ralph Christian Delos , Bautista Stephen James , Lucarelli Stefanie , Bone Leslie N. , Dayam Roya Monica , Abousawan John , Botelho Roberto , N. Antonescu Costin
Published: January 2023

Clathrin-mediated endocytosis is a major regulator of cell-surface protein internalization. Clathrin and other proteins assemble into small invaginating structures at the plasma membrane termed clathrin-coated pits (CCPs) that mediate vesicle formation. In addition, epidermal growth factor receptor (EGFR) signaling is regulated by its accumulation within CCPs. Given the diversity of proteins regulated by clathrin-mediated endocytosis, how this process may distinctly regulate specific receptors is a key question. We examined the selective regulation of clathrin-dependent EGFR signaling and endocytosis. We find that perturbations of phospholipase Cγ1 (PLCγ1), Ca2+, or protein kinase C (PKC) impair clathrin-mediated endocytosis of EGFR, the formation of CCPs harboring EGFR, and EGFR signaling. Each of these manipulations was without effect on the clathrin-mediated endocytosis of transferrin receptor (TfR). EGFR and TfR were recruited to largely distinct clathrin structures. In addition to control of initiation and assembly of CCPs, EGF stimulation also elicited a Ca2+- and PKC-dependent reduction in synaptojanin1 recruitment to clathrin structures, indicating broad control of CCP assembly by Ca2+ signals. Hence EGFR elicits PLCγ1-calcium signals to facilitate formation of a subset of CCPs, thus modulating its own signaling and endocytosis. This provides evidence for the versatility of CCPs to control diverse cellular processes.
pH of endophagosomes controls association of their membranes with Vps34 and PtdIns(3)P levels
Authors: Naufer Amriya , Hipolito Victoria E. B. , Ganesan Suriakarthiga , Prashar Akriti , Zaremberg Vanina , Botelho Roberto , R. Terebiznik Mauricio
Published: January 2023

Phagocytosis of filamentous bacteria occurs through tubular phagocytic cups (tPCs) and takes many minutes to engulf these filaments into phagosomes. Contravening the canonical phagocytic pathway, tPCs mature by fusing with endosomes. Using this model, we observed the sequential recruitment of early and late endolysosomal markers to the elongating tPCs. Surprisingly, the regulatory early endosomal lipid phosphatidylinositol-3-phosphate (PtdIns(3)P) Persists on tPCs as long as their luminal pH remains neutral. Interestingly, by manipulating cellular pH, we determined that PtdIns(3) P behaves similarly in canonical phagosomes as well as endosomes. We found that this is the product of a pH-based mechanism that induces the dissociation of the Vps34 class III phosphatidylinositol-3-kinase from these organelles as they acidify. The detachment of Vps34 stops the production of PtdIns(3)P, allowing for the turnover of this lipid by PIKfyve. Given that PtdIns(3)P-dependent signaling is important for multiple cellular pathways, this mechanism for pH-dependent regulation of Vps34 could be at the center of many PtdIns(3)P-dependent cellular processes. 
Multiscale interactome analysis coupled with off‑target drug predictions reveals drug repurposing candidates for human coronavirus disease
Authors: G. Sugiyama Michael , Cui Haotian , Redka Dar’ya
S. , Karimzadeh Mehran , Rujas Edurne , Maan Hassaan , Hayat Sikander , Cheung Kyle , Misra Rahul , McPhee Joseph , Viirre Russell , Haller Andrew , Botelho Roberto , Karshafian Raffi , Sabatinos Sarah , Fairn Gregory D. , Tonekaboni Seyed Ali Madani , Windemuth Andreas , Julien Jean-Philippe , Shahani Vijay , MacKinnon Stephen S. , Wang Bo , N. Antonescu Costin
Published: January 2023

 

The COVID-19 pandemic has highlighted the urgent need for the identification of new antiviral drug therapies for a variety of diseases. COVID-19 is caused by infection with the human coronavirus SARS-CoV-2, while other related human coronaviruses cause diseases ranging from severe respiratory infections to the common cold. We developed a computational approach to identify new antiviral drug targets and repurpose clinically-relevant drug compounds for the treatment of a range of human coronavirus diseases. Our approach is based on graph convolutional networks (GCN) and involves multiscale host-virus interactome analysis coupled to off-target drug predictions. Cell-based experimental assessment reveals several clinically-relevant drug repurposing candidates predicted by the in silico analyses to have antiviral activity against human coronavirus infection. In particular, we identify the MET inhibitor capmatinib as having potent and broad antiviral activity against several coronaviruses in a MET-independent manner, as well as novel roles for host cell proteins such as IRAK1/4 in supporting human coronavirus infection, which can inform further drug discovery studies.

 
Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity
Authors: Saffi Golam T. , Wang Cheng An , Mangialardi Emily M. , Vacher Jean , Salmena Leonardo , Botelho Roberto
Published: January 2023

Lysosome membranes contain diverse phosphoinositide (PtdIns) lipids that coordinate lysosome function and dynamics. The PtdIns repertoire on lysosomes is tightly regulated by the actions of diverse PtdIns kinases and phosphatases; however, specific roles for PtdIns in lysosomal functions and dynamics are currently unclear and require further investigation. It was previously shown that PIKfyve, a lipid kinase that synthesizes PtdIns(3,5)P2 from PtdIns(3)P, controls lysosome “fusion-fission” cycle dynamics, autophagosome turnover, and endocytic cargo delivery. Furthermore, INPP4B, a PtdIns 4-phosphatase that hydrolyzes PtdIns(3,4)P2 to form PtdIns(3)P, is emerging as a cancer-associated protein with roles in lysosomal biogenesis and other lysosomal functions. Here, we investigated the consequences of disrupting PIKfyve function in Inpp4b-deficient mouse embryonic fibroblasts. Through confocal fluorescence imaging, we observed the formation of massively enlarged lysosomes, accompanied by exacerbated reduction of endocytic trafficking, disrupted lysosome fusion-fission dynamics, and inhibition of autophagy. Finally, HPLC scintillation quantification of 3H-myo-inositol labeled PtdIns and PtdIns immunofluorescence staining, we observed that lysosomal PtdIns(3)P levels were significantly elevated in Inpp4b-deficient cells due to the hyperactivation of phosphatidylinositol 3-kinase catalytic subunit VPS34 enzymatic activity. In conclusion, our study identifies a novel signaling axis that maintains normal lysosomal homeostasis and dynamics, which includes the catalytic functions of Inpp4b, PIKfyve, and VPS34.

 