bluuebunny/crossref_metadata_2025 huggingface dataset:
Análise do gerenciamento de resíduos sólidos urbanos através de indicadores de sustentabilidade no município de Uiraúna-PB
Authors: Freitas Erverton Cezário de , Barros José Deomar de Souza
Published: October 2021

Com a expansão das cidades e o crescimento populacional possibilitou o consumo exagerado de produtos industrializados aumentando assim seu descarte de modo acelerado. Tendo em vista o avanço das tecnologias com o passar dos anos, os produtos foram mudando sua composição de modo que seu descarte em locais inadequados permitiu a contaminação do meio ambiente. Dentro desse contexto, a realidade de alguns municípios brasileiros, principalmente nas cidades do interior do país, ainda descartam seus resíduos de forma inadequada provocando impactos ambientais e perda da qualidade de vida da população, constituindo assim um dos principais problemas a serem solucionados atualmente. Neste sentido, vários estudos vêm sendo apresentados com relação a essa problemática buscando melhorias e desenvolvendo estratégias que possam mitigar ou na melhor situação para resolução da problemática do gerenciamento de resíduos sólidos urbanos. Tendo-se em vista essa realidade, a presente pesquisa teve como objetivo analisar o gerenciamento de resíduos sólidos por meio de indicadores de sustentabilidade na Cidade de Uiraúna-PB. O estudo em questão contém abordagens tanto quantitativas como qualitativas sobre a disposição desses rejeitos. A metodologia empregada para o desenvolvimento da pesquisa foi baseada em Castro (2016) seguindo o modelo adaptado por Bento (2020) de modo que os indicadores foram convertidos de qualitativos para quantitativos para que ocorra uma melhor compreensão dos dados coletados. As informações foram coletadas através da aplicação de questionário a diferentes grupos de atores sociais residentes no município de Uiraúna-PB. Após avaliação dos dados, verificou-se que dentre os trinta e sete (37) indicadores avaliados, vinte (20) foram considerados favoráveis e treze (13) desfavoráveis, porém é importante ressaltar que a maioria dos indicadores que foram destacados como favoráveis são referentes a perguntas de conhecimento e opinião sobre o manejo, coleta, destinação final adequada dos resíduos e de como esses resíduos sólidos urbanos (RSU) poderiam afetar a população quando não acondicionado de forma regular. Enquanto que as desfavoráveis estavam voltadas para questões mais relevantes como inexistência de local apropriado para o descarte final de resíduos, vazadouros a céu aberto próximo as residências, contaminação de populares através desses resíduos. Dentro dessa perspectiva o estudo destacou a urgência que o município de Uiraúna-PB apresenta para que haja mudanças em seu gerenciamento de resíduos sólidos urbanos.

Palavras chave: Crescimento populacional, produtos industrializados, prejuízo ambiental, indicadores.
Cultura e religião
Authors: Suess Paulo
Published: October 2021

Refletir sobre a articulação entre cultura e religião na América Latina é uma tarefa difícil. Por um lado estamos frente a uma grande diversidade de dados religiosos e culturais que uma multiplicidade de escolas e disciplinas se incumbiram de processar. A diversidade religiosa-cultural deste continente é de natureza sincrônica e diacrônica. Culturas arcaicas vivem no interior da modernidade transnacional e começam a agonizar no seio da civilização tecnológica, por não terem tempo suficiente para uma adaptação orgânica. Somos contemporâneos de crenças animistas, politeístas e monoteístas. A modernidade “importada” põe a todas em crise...
Dogma e culturas
Authors: Antoniazzi Alberto
Published: October 2021

A questão que me foi confiada é a seguinte: “Como a questão cultural influenciou a formulação dos dogmas?” Ela contém um aspecto histórico, que se revela no tempo do verbo: Como influenciou...? Mas também podemos ver implícita na pergunta uma questão teorética ou teológica: Como a cultura deve influenciar o dogma? (e ainda se poderia acrescentar, a partir do programa desta Semana de Missiologia: para uma Missão libertadora?”). É disso que trataremos: dando maior atenção ao primeiro aspecto, histórico, mas também tomando-o como base para algumas conclusões de caráter mais geral, teológicas.

No espaço de que nos é dado dispor, é evidentemente impossível esboçar uma história completa, mesmo em grandes linhas, das relações entre dogma (católico) e culturas. Seria o trabalho de uma vida inteira! Melhor, seria o trabalho de uma equipe de especialistas (como nas recentes “Histórias dos dogmas”, que contudo geralmente pouco consideram o contexto cultural). Tomaremos em exame dois momentos fundamentais da história do dogma católico, já bastante estudados e discutidos, que deverão fornecer a base para uma avaliação global da questão.
Mulher, Cultura e Igreja
Authors: Muraro Rose Marie
Published: October 2021

Se considerarmos a cultura como o princípio organizador das sociedades humanas, observaremos que ela terá que ser definida como o princípio que determina a relação do ser humano consigo mesmo; com os outros seres humanos; com os seres do outro sexo; com o meio ambiente em que o grupo vive e finalmente com a transcendência...
Pengaruh lama maserasi daun ketapang merah (Terminalia Catappa L.) terhadap daya hambat Staphylococcus aureus dan Escherichia coli
Authors: Pamudi Berwi Fazri , Munira Munira , Saha Rizky Amalia , Nasir Muhammad
Published: October 2021

Background: Bengal Almond leaves (Terminalia catappa L.) contain alkaloids, saponins, tannins, polyphenols, quinones, flavonoids and triterpenoids that can function as antibacterial.Objectives: This research was conducted to determine the effect of maceration time of red ketapang leaves (Terminalia catappa L.) on the growth of Staphylococcus aureus and Escherichia coli. Methods: This study was experimental using a completely randomized design (CRD) consisting of 6 treatments, that P0 (aquades), P1 (red ketapang leaf extract with 1 day maceration time), P2 (2 days maceration) P3 (3 days maceration) , P4 (4 days maceration) and P5 (5 days maceration) with 4 replications.Results: Anova test showed that macerated red ketapang leaf extract significantly affected the growth of Staphylococcus aureus and Escherichia coli (p= 0.000). Duncan's further test showed that the largest inhibition zone diameter in Staphylococcus aureus was formed by P2 (2 days maceration time) which was 18.62 mm and there was no significant difference between treatments. Meanwhile, the largest inhibition zone diameter against Escherichia coli was formed by P1 (1 day maceration time) which was 20.25 mm and there was a significant difference between treatments. Conclusion: Ketapang red leaf extract with different maceration times can inhibit the growth of Staphylococcus aureus and Escherichia coli.
Estudio sobre competencias digitales en programas de formación virtual y a distancia
Authors: Silva Monsalve Alexandra Maria , Martínez Morales Edgar Mauricio , Ortega Ferreira Sandra Constanza , Mejía Corredor Carolina , Maldonado Currea Adriana
Published: October 2021

Se examinan las fortalezas y las debilidades en el manejo tecnológico para programas en las modalidades virtual y a distancia, ya que las competencias digitales se han convertido en una habilidad necesaria para la educación en el siglo XXI. Metodológicamente, se lleva a cabo una investigación de tipo mixto y una revisión de la literatura para establecer un referente conceptual sobre competencias digitales. Asimismo, se identifica un instrumento para su validación, el cual se aplicó a estudiantes de dos universidades. Los resultados permiten establecer un referente conceptual situado en seis dimensiones y evidencian las categorías resultantes y su incidencia con el proceso de enseñanza y aprendizaje.
Geodiversidad y sus implicaciones en la conservación de la biodiversidad: algunos estudios de caso en el centro de México
Authors: Bravo-Cuevas Victor Manuel , González-Rodríguez Katia Adriana , Cabral-Perdomo Miguel Angel , Cuevas-Cardona Consuelo , Pulido-Silva María Teresa
Published: October 2021

La geodiversidad hace referencia a los componentes abióticos de la Tierra; sin embargo, en algunos casos se ha relacionado con la biodiversidad en términos de la conservación biológica. El registro fósil es uno de los componentes de la geodiversidad que evidencia la evolución de la biota en el pasado geológico y es de gran importancia en la propuesta de estrategias que conduzcan a una visión integral de la conservación de los recursos naturales. Es por ello que la paleobiología de la conservación es un área que integra información geológica y ecológica utilizada como evidencia para reconocer las modificaciones y alteraciones ambientales actuales. En este estudio se presentan algunos estudios de caso en México que muestran la relación entre la geodiversidad y biodiversidad en la conservación.
The central laboratory Coke Production of PJSC «ArcelorMittal Kryvyi Rih» in present-day condition.
Authors: Chernousova O.P. , Mukina N.V. , Martynova A.Yu.
Published: October 2021

THE CENTRAL LABORATORY OF COKE PRODUCTION AT PJSC «ARCELORMITTAL KRYVYI RIH» IN PRESENT-DAY CONDITIONS © O.P. Chernousova, N.V. Mukina (Coke Production of PJSC «ArcelorMittal Kryvyi Rih», 50095, Dnipropetrovsk region, Kryvyi Rih, Kryvorizhstal str., 1, Ukraine), A.Yu. Martynova, PhD in Technical Sciences (State Enterprise "Ukrainian State Research Coal Chemical Institute (UHIN)", 61023, Kharkov, Vesnina st., 7, Ukraine) The article discusses the scientific and methodological organization of analytical control at the coke production of PJSC "ArcelorMittal Kryvyi Rih" (CP AMKR), as well as the results of ongoing scientific and methodological measures to ensure confidence in the results of measurements carried out in the central laboratory (CL CP AMKR). Thus, the CL CP AMKR was one of the first in the industry to put into use the test installation "KARBOTEST", which allows without the involvement of third parties to carry out important laboratory research and enables the laboratory staff to quickly develop recommendations for optimizing the composition of coal charges and improving the quality of coke. The unit is designed to test the coking process of coal mixtures and certain grades of coal concentrates under temperature conditions similar to those in coke oven batteries. CL CP AMKR introduces express methods for the analysis of chemical coking products and was one of the first to introduce a refractometric method for determining the mass fraction of distillate up to 180 ° C in crude benzene. The use of this method can significantly reduce the measurement time, avoiding the cumbersome distillation procedure, and reduce the sample volume for analysis from 100 cm3 to a few drops. In order to ensure the uniformity, quality of measurements and tests, the CL on an ongoing basis takes part in interlaboratory comparative tests of almost all types of raw materials and products entering and produced by it. These are the products that are stable over time in terms of their quality indicators, for example, coal coke, as well as products whose individual indicators can change over time (crude benzene, coal tar, etc.). Keywords: measurement, quality control, coal concentrates, coke, chemical products, qualification confirmation, experimental coking, uncertainty, interlaboratory experiment, accreditation. Corresponding author A.P. Chernousova, е-mail: Elena.Chernousova@arcelormittal.com
Raw material base for coking of the Coke Production of PJSC "ARCELORMITTAL KRYVYI RIH" in the period from 2017 to 2021.
Authors: Mukina N.V. , Miroshnichenko D.V
Published: October 2021

RAW MATERIAL BASE FOR COKING OF THE COKING PRODUCTION OF PJSC "ARCELORMITTAL KRYVYI RIH" IN THE PERIOD FROM 2017 TO 2021 © N.V. Mukina (Coke-chemical production of PJSC "ArcelorMittal Kryvyi Rih", 50095, Dnepropetrovsk region, Kryvyi Rih, Krivorozhstal st., 1, Ukraine), D.V. Miroshnichenko, Doctor of Technical Sciences (NTU "Kharkiv Polytechnic Institute", 61002, Kharkiv, st. Kirpicheva, 2, Ukraine) The article presents the data on coal components that were used in the charge for coking coke oven batteries №№1-4 (bulk coal charge) and №№ 5, 6 (tamped coal charge) of the coke-chemical production of PJSC "ArcelorMittal Kryvyi Rih" in the period from 2017 to 2021, as well as averaged information on some quality indicators of the produced coke. In general, the coal raw material base of the enterprise for the last five years has been of a stable inter-basin nature with a predominance of coals from the USA, Kazakhstan, and the Russian Federation. It is shown that, as the tamping technology suggests, moisture content, bulk density and content of classes less than 0.16 and less than 3.0 mm in coal charges supplied to the coal waste plant. №№ 5, 6 are significantly higher than the values of similar indicators of coal charges supplied to the numbers 1-4. Along with this, due to the use of coals of a certain quality, ash content, total sulfur content and the thickness of the plastic layer in coal charges supplied to the coal bunker №№ 1-4, is slightly higher than similar indicators of coal charges supplied to the boiler №№ 5, 6. In total, during 2017-2021, the composition and quality indicators of the coal charge for the production of coke at the boiler plant №№ 1-4 practically did not change, while in the coal charge for the production of coke on coke oven batteries №№ 5, 6 there is a decrease in the share of highly volatile coals with a simultaneous increase in the content of medium-volatile and low-volatile components. The given values of the quality indicators of the obtained blast-furnace coke indicate that the use of tamping technology makes it possible to obtain blast-furnace coke of a higher quality than by using a traditional technology. In particular, the coke obtained at the oven batteries №№ 5, 6 are characterized by lower values of ash content, total sulfur content and abrasion (M10) with higher values of mechanical strength in terms of M25 and post-reaction strength (CSR). Keywords: coal, inter-basin raw material base, coking, charge tamping, coke quality. Corresponding author N.V. Mukina, е-mail: Natalia.Mukina@arcelormittal.com
SISTEM LELANG BOKAR PADA KOPERASI UNIT DESA BERKAT DI KABUPATEN MUARA ENIM PROPINSI SUMATERA SELATAN
Authors: Seli Ultha Marta , Badrudin Redy , Romdhon Muhamad Mustopa
Published: October 2021

Crumb rubber auction is ones of business unit of KUD Berkat, this is the biggest income contribution to the KUD. This research tries to explain the mechanism and the process of lump rubber auction at KUD Berkat. The study was conducted from April to May 2017. Determination of respondents using simple randomg sampling with a total of 58 respondents. The mechanism and process of the auction were explained by descriptive qualitative analysis. The research showed that the mechanism of lump rubber auction starting from rubber farmers to TPK (Cooperative Service Point) is then reported an auction was conducted at KUD Berkat. The factory is given a form to fill the bidding price on several TPK then read the winner of the auction. A week later weighed.
GHRLOS2 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of ghrelin opposite strand RNA 2 (non-protein coding), encoded by GHRLOS2 when comparing the primary tumors of triple negative breast cancer patients dead or alive. GHRLOS2 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Review Jurnal Pangan dan Gizi
Authors: Afika Dwi
Published: October 2021

Data terkait permasalahan stunting didukung oleh beberapa hasil penelitian yang menunjukkan adanya hubungan signifikan antara pola asuh ibu dengan kejadian stunting pada balita begitu juga dengan tingkat kognitif anak sangat dipengaruhi oleh stunting (Yena, 2017). Oleh karenannya melalui penelitian ini ingin mengetahui bagaimana pola asuh ibu terhadap kejadian stunting pada balita di Pesisir Kecamatan Tarowang Kabupaten Jeneponto.
Considerações da Educação Superior para a Treinamento Colaborativo
Authors: Garavit Jairit
Published: October 2021

Habitualmente, os alunos do ensino superior são convidados a colaborar em grupos para a obtenção de conhecimentos sólidos, examinando para ver em que medida e em que contextos se concretizam estes efeitos formativos, a investigação apresentada analisa a experiência de trabalho em grupo académico a partir das vivências dos professores. e alunos matriculados em várias universidades. Mobilizar um referencial teórico que articule abordagens motivacionais, desenvolvimentistas e cognitivas para o trabalho em grupo. Focando na experiência de avaliações em grupo, um dos benefícios das entrevistas foi elucidar os obstáculos para a implementação de interações verdadeiramente colaborativas.
OSBPL5 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of oxysterol binding protein-like 5, encoded by OSBPL5 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, OSBPL5 expression was correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. OSBPL5 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Etik Dan Hukum Profesi Perawat Dalam Pelaksanaan Praktik Keperawatan
Authors: Santoso Widi Ardian
Published: October 2021

Tenaga keperawatan yang melakukan tindakan keperawatan harus sesuai dengan kompetensi perawat yang sudah ditetapkan dan didapatkan selama proses pendidikan. Oleh karena itu, tanggung jawab hukum seorang perawat dalam menjalankan praktik mandiri keperawatan harus sesuai dengan standar pelayanan perawat, standar profesi, standar operasional dan kebutuhan kesehatan penerima pelayanan Kesehatan yang berfungsi untuk mengatur praktik keperawatan agar hak-hak masyarakat dalam memperoleh perawatan yang baik dapat terpenuhi
Bryan.19421038.sister.1.pdf
Authors: Bryan
Published: October 2021

Bryan.19421038.sister.1.pdf
Weißmüller & DeWaele (2021) - Would you Bribe your Lecturer? A Quasi-experimental Study on Burnout and Bribery in Higher Education
Authors: Weißmüller Kristina Sabrina , De Waele Lode
Published: October 2021

Bribery is a complex and critical issue in higher education (HE), causing severe economic and societal harm. Traditionally, most scholarship on HE corruption has focused on institutional factors in developing countries and insights into the psychological and motivational factors that drive HE bribery on the micro-level mechanisms are virtually non-existent. To close this research gap, this study investigates the connection between study-related burnout and university students’ willingness to offer bribes to their lecturers to pass important exams. Conducting a vignette-based quasi-experimental replication study with 624 university students in Germany, Belgium, and the Netherlands we find that university students in three countries differentiate sharply between different shades of bribery and that a majority accept using emotional influence tactics to pass (failed) exams. In contrast, offering a helping hand or money (i.e., darker shades of bribery) to their lecturer was less acceptable. Study-related burnout is associated with a higher likelihood of engaging in these darker shades of bribery and students’ commitment to the public interest is but a weak factor in preventing unethical behavior. In summary, this study provides solid empirical evidence that university students are likely to use emotional influence tactics violating both the ethical codes of conduct and the formalized bureaucratic procedures of HE examination, particularly if they suffer from study-related burnout. However, the accelerating effect of burnout on bribery is conditional in that it only holds for darker shades of bribery. HE institutions may benefit from implementing the four-eye principle and from launching awareness campaigns that enable lecturers to better recognize these tactics and engage students in creating a transparent environment for testing, grading, and collaboration that is resistant to bribery.
Diretrizes de Treinamento Remoto e Colaboração
Authors: Garavit Jairit
Published: October 2021

Incentivar os alunos a cooperar juntos em certas atribuições pode ajudar e dominar as concepções de ideias importantes e também expandir os tipos de habilidades colaborativas essenciais que são exigidas em várias esferas de trabalho ou treinamento. Embora o treinamento remoto exija alguns arranjos nas conveniências em que a colaboração tende a funcionar, uma vez que os alunos não estão fisicamente presentes no mesmo lugar, as representações síncronas e assíncronas da informação digital conseguem ser benéficas. Os exemplos de possíveis ações colaborativas podem variar de treinamentos conjuntos de brainstorming, demonstrações e objetivos conjuntos a interrogatórios virtuais realizados em sala de aula.
PGM2L1 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of phosphoglucomutase 2-like 1, encoded by PGM2L1 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, PGM2L1 expression was correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. PGM2L1 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
The heart of a scientist - virtue for a better future
Authors: Le Tam-Tri
Published: October 2021

I expressed my thoughts on the humanity sides behind scientific endeavors.
Hubungan antara Kualitas E-Service dengan Kepuasan Pelanggan
Authors: Kasde Fiona Ramadhita
Published: October 2021

Paper ini bertujuan untuk mengetahui adanya hubungan antara kualitas e-service dengan kepuasan pelanggan. Metode yang digunakan adalah mengumpulkan serta mempelajari literatur yang bersumber pada jurnal yang didapatkan dari internet. Dari jurnal-jurnal tersebut, ditemukan bahwa terdapat hubungan yang positif antara kualitas e-service dengan kepuasan pelanggan. Hal-hal yang perlu diperhatikan adalah bagaimana dalam suatu website memiliki informasi yang berkualitas, aman, fungsional, tanggap, dan memiliki hubungan yang erat dengan pelanggan.
Differential expression of IL24 in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of interleukin 24, encoded by IL24, in cancer of the vulva. IL24 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
Ryan Malvin Cornelius 2301895233 strategy LB21
Authors: Cornelius Ryan Malvin , syahchari dicky hida
Published: October 2021

tugas strategy lb21 osf
GSR expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of glutathione reductase, encoded by GSR when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, GSR expression was correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. GSR may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Chapter 1 Tổng quan Marketing (Marketing overview)
Authors: Tung Dao Duy
Published: October 2021

This first chapter introduces you to the basic concepts of marketing. Simply put, marketing is engaging customers and managing profitable customer relationships. The aim of marketing is to create value for customers in order to capture value from customers in return. Next, I discuss five concepts under organization design and marketing mix models (4P, 7P, 9P).
IMPLEMENTATION OF FATWA ULAMA COUNCIL ACEH CONCERNING MAINTAINING FARDHU KIFAYAH FOR THE MUSLIM’S CORPSE INFECTED BY COVID 19 IN BANDA ACEH 2021
Authors: nirwana andri
Published: October 2021

Abstract: The phenomenon of the people who forcibly took covid's corpse 19 from the hospital to be taken care of by Fardhu Kifayah by his family and the community, became a conclusion that there was community doubt about the management of Tajhiz Mayat conducted by the hospital. Coupled with the circulation of the video of the Ruku movement 'in the corpse prayer conducted by unscrupulous parties at the Hospital, became added doubts from the public against the hospital. To solve this problem, this research uses a Descriptive Analysis approach, namely by formulating a question, namely How to arrange Covid 19's body in Banda Aceh and this question will be answered with several theories and data sets from the field. So it was concluded in a conclusion that answered the formulation of the problems mentioned. Theoretically the spread of covid 19 is very fast, the size of the virus is only 0.1 micrometer and is in body fluids, especially nasopharyngeal fluid and oropharyngeal fluids of infected people, fluids in the body of covid 19 bodies can get out through every gap of the body such as mouth, nose, eye and rectum, because it requires special techniques in its management. Fardhu kifayah to covid 19 bodies should be carried out by trained Ustad and trained health workers, so that the spread stopped. The results of this study concluded that the management of the Moslem bodies died at Zainal Abidin Hospital in Banda Aceh was in accordance with the Fatwa of the Aceh Ulama Council (MPU) and the bodies were handled by trained Ustad and health workers.
Novel Fabrication Approach of a Porous Silicon Biocompatible Membrane Evaluated within a Alveolar Coculture Model
Authors: Williams Marcus A. C. , Wiens Cooper , Hamilton Adam , Mancha Sophie , Stalder Madeline , Vargas Koby , Crawford Jerry , Li Yiyan , Schreiner Sarah , Blake David J. , Jessing Jeffrey Richard
Published: October 2021

The use of conventional in vitro and preclinical animal models often fail to properly recapitulate the complex nature of human diseases and hamper the success of translational therapies in humans [1-3] Consequently, research has moved towards organ-on-chip technology to better mimic human tissue interfaces and organ functionality. Herein, we describe a novel approach for the fabrication of a biocompatible membrane made of porous silicon (PSi) for use in organ-on-chip technology that provides key advantages when modeling complex tissue interfaces seen in vivo. By combining well-established methods in the semiconductor industry with organ-on-chip technology, we have developed a novel way of producing thin (25 μm) freestanding PSi biocompatible membranes with both nano (~15.5 nm diameter pores) and macroporous (~0.5 μm diameter pores) structures. To validate the proposed novel membrane, we chose to recapitulate the dynamic environment of the alveolar blood gas exchange interface in alveolar co-culture. Viability assays and immunofluorescence imaging indicate that human pulmonary cells remain viable on the PSi membrane during long-term culture (14 days). Interestingly, it was observed that macrophages can significantly remodel and degrade the PSi membrane substrate in culture. This degradation will allow for more intimate physiological cellular contact between cells, mimicking a true blood-gas exchange interface as observed in vivo. Broadly, we believe that this novel PSi membrane may be used in more complex organ-on-chip and lab-on-chip model systems to accurately recapitulate human anatomy and physiology to provide further insight into human disease pathology and pre-clinical response to therapeutics.
Shape functions for high-order shear deformation beam element
Authors: Gaur Himanshu , Dawood Mahmoud , Manchiryal Ram Kishore
Published: October 2021

In this article, shape functions for higher-order shear deformation beam theory are derived. For the two nodded beam element, transverse deflection is assumed as cubic polynomial. By using equations of equilibrium of high-order theory that are already derived by J. N. Reddy in 1997, equation for slope of high- order theory is found. Finally with the boundary conditions of beam element and assumed kinematics of high-order theory, shape functions are derived.
Partisans’ Receptivity to Persuasive Messaging is Undiminished by Countervailing Party Leader Cues
Authors: Tappin Ben M
Published: October 2021

It is widely assumed that party identification and loyalty can distort partisans’ information processing, diminishing their receptivity to counter-partisan arguments and evidence. Here we empirically evaluate this assumption. We test whether American partisans’ receptivity to arguments and evidence is diminished by countervailing cues from in-party leaders (Donald Trump or Joe Biden), using a survey experiment with 24 contemporary policy issues and 48 persuasive messages containing arguments and evidence (N = 4,531; 22,499 observations). We find that, while in-party leader cues influenced partisans’ attitudes, often more strongly than the persuasive messages, there was no evidence that the cues meaningfully diminished partisans’ receptivity to the messages—despite them directly contradicting the messages. Rather, persuasive messages and countervailing leader cues were integrated as independent pieces of information. These results generalized across policy issues, demographic subgroups and cue environments, and challenge existing assumptions about the extent to which party identification and loyalty distort partisans’ information processing.
Does capability, opportunity, and motivation predict intentions to repeat self-isolation if required? An analysis of a national telephone survey with contacts of confirmed COVID-19 cases in Wales.
Authors: Lewis Lesley , Isherwood Kate , Kyle Richard G , Povey Rachel , Cowap Lisa , Clark-Carter David , Davies Alisha
Published: October 2021

ObjectiveSelf-isolation is a key strategy to prevent the transmission of COVID-19 and other infectious diseases. This study examined whether capability, opportunity, and motivation significantly predicted intentions to self-isolate again amongst COVID-19 contacts. DesignA cross-sectional survey was completed with 1,011 participants of the Contact Adherence Behavioural Insights Survey (CABINS), a larger within-subjects study. CABINS was a 15-minute telephone survey conducted with contacts of cases of COVID-19, identified through the national NHS Wales Test Trace Protect database between 12th September and 22nd October, 2020. Main Outcome MeasuresDeterminants of intention to self-isolate were derived from the British Psychological Society’s guidance on self-isolation and the COM-B model. Measures included intention to self-isolate again if required, and items related to psychological capability, physical and social opportunity, and reflective and automatic motivation.ResultsResults of a binary logistic regression indicated three significant predictors of self-isolate intent: (1) knowledge and understanding about self-isolation; (2) making plans to prepare for self-isolation; and (3) beliefs about the effectiveness of self-isolation. ConclusionThis study suggests that an increase in aspects of psychological capability and reflective motivation are associated with increases in self-isolation intent. Future pandemics or outbreaks of disease should target these factors prior to individuals self-isolating.
Approaching Structured Debate with Quantitative Ethnography in Mind
Authors: Scianna Jennifer , Kaliisa Rogers , Boisvenue Jamie , Zörgő Szilvia
Published: October 2021

Structured Debate (SD) is a constrained discourse style that is popular in many different forums. The expansion of SD to online platforms leaves many questions about addressing this type of data during analysis. Quantitative Ethnography (QE) may provide a framework for the considerations that need to be made when analyzing SD datasets. In this paper, we review the ways in which QE methods are compatible with SD and the challenges associated with applying this method. Using data from an online, SD forum, we present a narrative of decision-making throughout the analysis process. We find that QE allows for a myriad of insights to be gained from this form of data depending on the approach one takes including insights into structures, content, and participation. This work intends to serve as a model for researchers hoping to utilize QE on SD and, more broadly, for approaching novel datasets.
Die Behandlung mit Clozapin bei Patienten mit therapieresistenter Schizophrenie: Rationale, Dos und Don’ts
Authors: Qubad Mishal , Bittner Robert
Published: October 2021

Schizophrene Psychosen sind durch einen hohen Grad an durch Behinderung beeinträchtigter Lebensjahre aber auch deutlich beeinträchtigter Lebensqualität ge-kennzeichnet. Bei ca. 30 % der Patienten zeigt sich im Krankheitsverlauf eine The-rapieresistenz, d.h., eine unzureichende Response auf mehrere lege artis durchge-führte antipsychotische Standardtherapieversuche. Bei therapieresistenter Schizo-phrenie (TRS) ist Clozapin noch immer die einzige wirksame medikamentöse Be-handlungsoption. Hierbei ist Clozapin durch eine gute Wirksamkeit in verschiede-nen Symptomdimensionen charakterisiert. Neben der überlegenen Wirksamkeit bei Positivsymptomatik bestehen positive Effekte auf Negativsymptomatik. Weiterhin senkt Clozapin das Risiko für Suizidversuche und aggressives Verhalten stärker als andere Antipsychotika, gleiches gilt auch für komorbiden Substanzkonsum. Zudem weist Clozapin die stärkste Mortalitätsreduktion aller Antipsychotika auf. Von hoher Relevanz für eine optimale Wirksamkeit ist hierbei der frühzeitige Einsatz von Clo-zapin nach Feststellung einer Therapieresistenz. Trotz der nachgewiesenen Effekte wird Clozapin bei TRS weiterhin zu selten und meist Jahre zu spät verordnet. Haupthinderungsrund ist hierbei wahrscheinlich neben der unzureichenden An-wendung der Therapieresistenzkriterien und der damit verbundenen Leitlinienemp-fehlungen die noch immer weiter verbreitete Furcht vor Nebenwirkungen wie Agra-nulozytose und Myokarditis. Das Ziel dieser Übersichtsarbeit ist es, der ungerecht-fertigten Zurückhaltung beim Einsatz von Clozapin entgegen zu wirken, indem ak-tuelle Erkenntnisse zu den umfassenden positiven Effekten von Clozapin und evi-denzbasierte Handlungsempfehlungen für ein optimales Nebenwirkungsmanage-ments dargestellt werden. Weiterhin werden evidenzbasierte Augmentationsstrate-gien für den Fall einer unzureichenden Therapieresponse unter Clozapin darge-legt.
Multimodal connectome biomarkers of cognitive and affective dysfunction in the common epilepsies
Authors: rodriguez-cruces raul , Royer Jessica , Lariviere Sara , Bassett Danielle S , Caciagli Lorenzo , Bernhardt Boris C.
Published: October 2021

Epilepsy is one of the most common chronic neurological conditions, traditionally defined as a disorder of recurrent seizures. Cognitive and affective dysfunctions are increasingly recognized as core disease dimensions and can affect patient wellbeing sometimes more than the seizures themselves. Connectome- based approaches hold immense promise for revealing mechanisms that contribute to dysfunction, and to identify biomarkers. Our review discusses emerging multimodal neuroimaging and connectomics studies that highlight network substrates of cognitive/affective dysfunction in the common epilepsies. We first overview work in drug-resistant epilepsy syndromes i.e., temporal lobe epilepsy related to mesiotemporal sclerosis (TLE) and extratemporal epilepsy (ETE) related to malformations of cortical development. While these are traditionally conceptualized as ‘focal’ epilepsies, many patients present with broad structural and functional anomalies. Moreover, the extent of distributed changes contributes to difficulties in multiple cognitive domains as well as affective-behavioral challenges. We will also review work in idiopathic generalized epilepsy (IGE), a class of generalized epilepsy syndromes that involve subcortico-cortical circuits. Overall, neuroimaging and network neuroscience studies point to both shared and syndrome specific connectome signatures of dysfunction across TLE, ETE, and IGE. Lastly, we point to current gaps in the literature and formulate recommendations for future research.
Implicit and explicit safety evaluation of foods: The importance of food processing
Authors: Coricelli Carol , Rumiati Raffaella I , rioux camille
Published: October 2021

Identifying beneficial foods in the environment, while avoiding ingesting something toxic is a crucial task humans face on a daily basis. Here we directly examined adults’ implicit and explicit safety evaluations of the same foods presented with different degrees of processing, ranging from unprocessed (raw) to processed (cut or cooked). Moreover, we investigated whether individual characteristics (e.g., Body Mass Index, food neophobia and hunger) modulated their evaluations. We hypothesized that adults would associate the processed form of a food with safety more than its unprocessed form since processing techniques, which are ubiquitously applied in different cultures, often reduce the toxicity of foods, and signal previous human intervention and intended consumption. Adults (N = 109, 43 females) performed an implicit Go/No-Go association task (GNAT) online, assessing the association between safety attributes and food images differing on their degree of processing; both unfamiliar and familiar foods were used. Then, each food was explicitly evaluated. Results revealed that individual characteristics affected both implicit and explicit evaluations. Individuals with overweight and obesity had a strong and positive implicit association between processed foods and safety attributes, but explicitly rated cooked foods as the least safe overall, this latter result was found in highly neophobic individuals as well. Yet, at the explicit level, when looking at unfamiliar foods only, processed foods were rated safer than unprocessed foods by all participants. Our results are the first evidence that directly highlights the relevance of the degree of processing in food safety evaluation and suggest that thinking of the important tasks humans face regarding food selection enriches our understanding of food behaviors.
Of Precarity and Conspiracy: Introducing A Socio-Functional Model of Conspiracy Beliefs
Authors: Adam-Troian Jais , Chayinska Maria , Paladino Maria Paola , Uluğ Özden Melis , Vaes Jeroen , Wagner-Egger Pascal
Published: October 2021

Conspiracy Beliefs (CB) are a key vector of violent extremism, radicalism and unconventional political events (e.g. Brexit). So far, social-psychological research has extensively documented how cognitive, emotional and intergroup factors can promote CB. Evidence also suggests that adherence to CB moves along social class lines: low-income and low-education are among the most robust predictors of CB (Uscinski, 2020; van Prooijen, 2017). Yet, the potential role of precarity – the subjective experience of permanent insecurity stemming from objective material strain – in shaping CB remains largely unexplored. In this paper, we propose for the first time a socio-functional model of CB. We test the hypothesis that precarity could foster increased CB because it undermines trust in government and the broader political “elites”. Data from the World Value Survey (n = 21,650; Study 1, electoral CB) and from representative samples from polls conducted in France (n = 1760, Study 2a, conspiracy mentality) and Italy (n = 2196, Study 2b, COVID-19 CB), corroborate a mediation model whereby precarity is directly and indirectly associated with lower trust in authorities and higher CB. In addition, these links are robust to adjustment on income, self-reported SES and education. Considering precarity allows for a truly social psychological understanding of CB as the by-product of structural issues (e.g. growing inequalities). Results from our socio-functional model suggest that implementing solutions at the socio-economic level could prove efficient in fighting CB.
Reduced semantic context and signal-to-noise ratio increase listening effort as measured using functional near-infrared spectroscopy
Authors: Rovetti Joseph , Goy Huiwen , Zara Michael , Russo Frank
Published: October 2021

Objectives: Understanding speech in noise can be highly effortful. Decreasing the signal-to-noise ratio (SNR) of speech increases listening effort, but it is relatively unclear if decreasing the level of semantic context does as well. The current study used functional near-infrared spectroscopy (fNIRS) to evaluate two primary hypotheses: (1) listening effort (operationalized as oxygenation of the left lateral PFC) increases as the SNR decreases and (2) listening effort increases as context decreases. Design: Twenty-eight younger adults with normal hearing completed the Revised Speech Perception in Noise (R-SPIN) Test, in which they listened to sentences and reported the final word. These sentences either had an easy SNR (+4 dB) or a hard SNR (-2 dB), and were either low in semantic context (e.g., “Tom could have thought about the sport”) or high in context (e.g., “She had to vacuum the rug”). PFC oxygenation was measured throughout using fNIRS. Results: Accuracy on the R-SPIN Test was worse when the SNR was hard than when it was easy, and worse for sentences low in semantic context than high in context. Similarly, oxygenation across the entire PFC (including the left lateral PFC) was greater when the SNR was hard, and left lateral PFC oxygenation was greater when context was low. Conclusions: These results suggest that activation of the left lateral PFC (interpreted here as reflecting listening effort) increases to compensate for acoustic and linguistic challenges. This may reflect the increased engagement of domain-general and domain-specific processes subserved by the DLPFC (e.g., cognitive control) and IFG (e.g., predicting the sensory consequences of articulatory gestures), respectively.
SKILT study protocol
Authors: Bruijniks Sanne , Werthmann Jessica , Renner Fritz
Published: October 2021

currently under review
UNGKAP PERMASALAHAN KLIEN MELALUI VISUAL ART IN COUNSELING
Authors: Christanti Anandita
Published: October 2021

Klien yang datang pada konselor tentu memiliki suatu bahkan segudang permasalahan. Namun tidak jarang dari mereka tidak tau cara menceritakan masalahnya atau memulai mengungkapkan apa yang mereka alami. Konseling ekspresif merupakan suatu cara agar konseli mampu mengekspresikan permasalahannya. Dengan melakukan konseling ekspresif konselor dapat membantu klien untuk mengeksplorasi dan mengungkapkan perasaannya melalui seni. Kombinasi antara konseling ekspresif dengan visual art mengungkapkan permasalahan konseli melalui berbagai cara seperti mewarnai, menggambar, dan mematung. Visual art in counseling menjadi suatu solusi ataupun alternatif bagi konselor untuk membantu kliennya yang mengalami kesulitan dalam mengungkapkan permasalahan mereka. Suatu proses konseling akan menjadi suatu proses yang bermakna dan berkualitas karena konselor mampu membongkar pertemuan konseling yang konvensional, membangun rapport dengan kliennya, mengetahui isi hati klien, tujuan klien, dan pada akhirnya konselor dapat menemukan akar masalah dari klien. Maka dari itu visual art in counseling dapat digunakan untuk mengungkapkan masalah dari klien.
Emotional Intelligence and Its Relationship with Demographic Variables and Job Satisfaction: A Study Among University-Level Teachers in Nepal
Authors: Chapagain Bal Ram
Published: October 2021

Given the importance of emotional intelligence (EI) in teaching, this study aims to identify the status of EI of university-level teachers and examine its relationship with various demographic variables and job teachers in Nepal is moderately high. Among the four demographic variables, only the gender, in favour job satisfaction. Since females are found to be more emotionally intelligent than males, strategies to include more females in the faculty pool could be an important step for higher education institutions EI in relation to demographic variables and job satisfaction in Nepalese higher education, and hence this work could be a springboard for more advanced research.
Performance of Lettuce (Lactuca Sativa L.) Genotypes with Respect to Morphological, Yield and Quality Traits at Two Localities of Nepal
Authors: Dahal Januka , Pandey Utshay , Bhandari Upakar , Tiwari Sabina , Shrestha Suchit
Published: October 2021

Lettuce is cultivated as minor crop in Nepal. However, people are becoming more health conscious in these days and demand for salad is increasing in food.  The demand of lettuce is also gradually increasing but relatively few farmers are involved in this crop due to the lack of high-yielding and good quality genotypes. The research was conducted at two locations of Nepal; Kavre and Kaski with the aim of evaluating the performance of seven different hybrid lettuce genotypes in terms of its morphology, yield, and quality. The research was laid out on Randomized Complete Block Design with three replications at each location. Two types of lettuce were used on the research i.e. head type and leaf type. Among the head type, genotype Iceberg performed better with more plant spread (51 cm), head diameter (14.7 cm) and yield (738.4 g at Kavre and 725.8 g at Kaski) than other head type lettuce genotypes and among leaf type variety Green Oak was recorded with highest numbers of leaves (67 at Kavre and 40 at Kaski) and yield (572.3 g at Kavre and 641.9 g at Kaski). So, among head type lettuce genotypes Iceberg performed better as this had better plant spread, large head diameter, more yield and sweet flavor. Among leaf type genotypes Variety Green Oak was found most suitable for Nepali Market as this variety had highest number of leaves and yield among leaf type lettuce genotypes.
Actualización del asma
Authors: Franken Morales Saskia Sharielle , Garcia Orrego Ana Maria , Pabón Bonilla Dennis
Published: October 2021

El asma debido a sus características clínicas, fisiológicas y patológicas se define como una enfermedad heterogénea, caracterizada por inflamación crónica de las vías aéreas, con manifestaciones clínicas, como lo son las sibilancias, dificultad respiratoria, opresión torácica y tos, junto con una limitación variable del flujo aéreo espiratorio, las cuales varían en su intensidad a lo largo del tiempo.  La inflamación de la vía aérea está asociada con un aumento en la reactividad de las mismas, al exponerse a diversos estímulos, y como consecuencia producen un descenso del flujo aéreo, ocasionando broncoconstricción, tapones de moco y aumento de la inflamación.                                                                                                                            
El diagnóstico de asma se confirma con espirometría: VEF1 (volumen espiratorio forzado del primer segundo) / CVF (capacidad vital forzada) < 80%, con reversibilidad (VEF1 > 12% o 200 mL) tras utilizar broncodilatador.    El principal objetivo del tratamiento es lograr y mantener el control de los síntomas, además de prevenir el riesgo de exacerbaciones.