bluuebunny/crossref_metadata_2025 huggingface dataset:
Rehabilitation program of post-COVID-19 syndrome with the use of nitric oxide and molecular hydrogen
Authors: Pozdnyakova Darya D. , Bakhareva Tatiana А. , Baranova Irina A. , Selemir Victor D. , Chuchalin Alexander G.
Published: April 2024

Рost-COVID-19 syndrome (PS) is one of the medical and social problem. According to WHO, 10–20% of COVID-19 patients suffer from PS. The use of medical gases – inhaled nitric oxide (iNO) and molecular hydrogen (iH2) – may influence on the mechanisms of development PC.
Aim. To evaluate the safety and efficacy of the combined inhalation of NO and H2 (iNO/iH2) in patients with respiratory manifestations of PS.
Materials and methods. 34 patients with PS (11 men/23 women, 60.0±11.7 years) were included in the prospective open-label controlled study in parallel groups: the main group (n=17) received iNO/iH2 for 90 minutes once a day for 10 days (concentration of NO 60 ppm, H24% in the gas mixture), the control group (n=17) didn’t receive inhalations. The period from the confirmation of COVID-19 to the start of the study was 641.8±230.5 days. The groups did not differ in the baseline parameters. The clinical symptoms (from the self-observation diary and mMRC questionnaires, "dyspnea language"), FAS, HADS, SF-36 scores, 6-minute walk test, the blood serum parameters of oxidative stress, the dynamics of the microcirculation in the eye bulbar conjunctiva were evaluated. The individual dose of iNO has chosen during a 15-minute test (the positive dynamics of the microcirculation have indicated that the dose was selected correctly).
Results. The decrease the symptoms severity, such as dyspnea, cough, fatigue and palpitations (p0.005), the increase in SF-36 questionnaire scores (p=0.006) and a reducing of FAS score (p=0.001), as well as the anxiety component of HADS (p=0.02) were revealed at the end of treatment in the main group compared to the control group. We observed an improvement in distance walked (p=0.01) and the values SpO2 (p=0.04) in 6-minute walk test, the increase in the volumetric blood flow velocity in venules (p0.001), and the date in oxidative damage (p0.001) and antioxidant activity (p=0.03) parameters in the blood serum.
Conclusion. The results of the study demonstrate clinical efficacy iNO/iH2 on clinical indicators, parameters of oxidative stress and microcirculation in patients with PS.
Results of a randomized double-blind multicenter clinical trial of the efficacy and safety of the drug riamilovir for the prevention of COVID-19
Authors: Sabitov Alebai U. , Lioznov Dmitry A. , Zhdanov Konstantin V. , Tihonova Elena P. , Esaulenko Elena V. , Sorokin Pavel V.
Published: April 2024

Aim. Evaluation of the efficacy and safety of riamilovir as a drug for the prevention of coronavirus infection (COVID-19) in adults who have constant contact with COVID-19 patients as a result of living together.
Materials and methods. The study included 750 adult participants living with patients with confirmed polymerase chain reaction method COVID-19, who had a negative polymerase chain reaction result for the SARS-CoV-2 virus at the initial level, met the criteria for inclusion, non-inclusion and exclusion, and signed a voluntary informed consent to participate in a clinical trial.
Results. The efficacy, good tolerability and safety of the drug riamilovir for the prevention of COVID-19 infection among people who have come into contact with COVID-19 patients in a family focus of infection have been established.
Conclusion. As a result of a multicenter randomized double-blind clinical trial, the effectiveness of the drug riamilovir for the prevention of COVID-19 infection was established. It was shown that the relative risk of disease in the group taking riamilovir for prophylaxis was 88.96% lower than in the control group. Based on the results of a clinical trial, in October 2023 Ministry of Health of the Russian Federation approved the inclusion of a new indication (prophylaxis of COVID-19 infection) in the instructions for the medical use of the drug riamilovir (trade name – Triazavirin®).
Antibacterial therapy for acute streptococcal tonsillopharyngitis: results of a randomized comparative clinical trial with amoxicillin + clavulanic acid EXPRESS
Authors: Karpishchenko Sergey A. , Ryabova Marina А. , Kolesnikova Olga M. , Ulupov Mikhail Yu.
Published: April 2024

Background. Acute tonsillopharyngitis is one of the most common types of respiratory tract infections. In case of bacterial etiologies of the disease, penicillin antibiotics are prescribed, in particular amoxicillin + clavulanic acid. Dispersible forms of antibiotics have a number of advantages over film-coated tablets and are characterized by better pharmacokinetic parameters that increase the effectiveness and safety of treatment, as well as patient compliance.
Aim. To compare the effectiveness and safety of Amoxicillin + Clavulanic acid EXPRESS in the form of dispersible tablets and amoxicillin with clavulanic acid in film-coated tablets in the treatment of acute streptococcal tonsillopharyngitis.
Materials and methods. A randomized comparative clinical study involved 60 adult patients diagnosed with acute streptococcal tonsillopharyngitis. Group 1 (n=30) received the Amoxicillin + Clavulanic acid EXPRESS, dispersible tablets, 875+125 mg 2 times a day at the beginning of meals. Group 2 (n=30) received Amoxiclav, film-coated tablets, 875+125 mg 2 times a day at the beginning of meals. The duration of the treatment was 10 days. The following procedures were performed to all participants: general clinical and otorhinolaryngological examinations, an express test to detect group A streptococcal antigens in a smear from the posterior pharyngeal wall (streptatest), assessment of symptoms of acute tonsillopharyngitis on the McIsaac scale, severity of sore throat, difficulty swallowing, swelling of the throat, measurement of body temperature, assessment of the clinical global impression of the therapy, adherence to treatment, frequency of the adverse reactions before treatment, 3 days after the beginning of therapy and after the course completion (day 10).
Results. Recovery occurred in 96.6% of patients in group 1 according to examination on the 10th day of treatment and in 93.3% of patients in group 2. The rate of fever regression was higher in group 1 – on the 3rd day of treatment, normalization of temperature was observed in 36.6% and 30% of patients in the comparison group. Pain syndrome, symptoms of throat swelling and difficulty swallowing significantly (p0.01) regressed by the 10th day in patients of both treatment groups. The incidence of adverse reactions on the 10th day of treatment in group 1 was 10%, in group 2 – 33.3% (p=0.03).
Conclusion. Amoxicillin + Clavulanic acid EXPRESS has high therapeutic efficacy in the treatment of acute streptococcal tonsillopharyngitis, comparable to the Amoxiclav in film-coated tablets. At the same time, dispersible tablets of Amoxicillin + Clavulanic acid EXPRESS demonstrated a significantly higher safety profile compared to the simple tablet form.
Autorregulación del aprendizaje en estudiantes de primer año del programa de Administración en Salud Ocupacional
Authors: Másmela Olivar Rodrigo , Mahecha-Escobar Jenny , Conejo-Carrasco Francisco
Published: April 2024

Uno de los principales retos para los estudiantes universitarios de los primeros semestres es asumir el rol de agente activo en los procesos de aprendizaje autónomo. Para enfrentar estos nuevos procesos, los estudiantes deben potenciar las características metacognitivas, afectivas y de autoeficacia necesarias en la autorregulación del aprendizaje. Desde esta perspectiva, el objetivo del estudio fue caracterizar los procesos de aprendizaje autorregulado en estudiantes de los dos primeros niveles de un Programa de Administración en Salud Ocupacional. La población de estudiantes registró altos niveles de aprendizaje autodirigido. En contraste, los procesos dimensionales motivacionales, meta cognitivos, y relacionados a las fases del aprendizaje autorregulado (previa, realización y autorreflexión) tuvieron puntajes promedios moderados, cercanos a bajos con una alta dispersión, por lo tanto, es necesario que en los planes de gestión del aprendizaje de las universidades se considere un plan de acción para mejorar estos indicadores en los estudiantes de primeros semestres.
Experiencias significativas de la implementación de la gamificación en los cursos de programación de computadores
Authors: Ramírez Paulo , Ortiz-Beltran Ariel , Lobo-Quintero René
Published: April 2024

Este articulo presenta un compendio de experiencias de la implementación de metodologías pedagógicas basadas en gamificación usados en los cursos de programación de computadores en el programa de Ingeniería de Sistemas de la Universidad Autónoma de Bucaramanga, con el propósito de sintetizar una metodología única y repetible para orientar a futuros docentes en el correcto uso de la gamificación en el aula de clase. Igualmente se incluyen elementos del Gamification Model Canvas el cual sirvió como base para la metodología desarrollada
Acreditación internacional de carreras de ingeniería
Authors: Peláez Valencia Luis Eduardo , Trefftz Helmuth , Delgado-González Iván Andrés
Published: April 2024

Las Instituciones de Educación Superior (IES) están en la búsqueda permanente de herramientas, que les permitan ofrecer un servicio de educación superior en óptimas condiciones de calidad en todas las profesiones y disciplinas que ofrecen a través de sus programas académicos. Para lograrlo, encuentran los procesos de acreditación en alta calidad como el sello que les reconoce su trabajo y su madurez para ofrecer un buen servicio, y la manera de hacer llegar a la sociedad en general su compromiso con la calidad enmarcado en un proceso de evaluación y acreditación por parte de una entidad externa. En este trabajo, se presenta la exploración del estado de la cuestión para la acreditación internacional en alta calidad de los programas de Ingeniería. Particularmente, las propuestas contempladas por los modelos de ABET, EUR-ACE y ARCU-SUR. Su propósito es que las IES, y particularmente las facultades de ingeniería, conozcan las alternativas más comunes, su impacto y el valor agregado en cada caso.
Articulación de espacios curriculares para el desarrollo de competencias en la enseñanza de Ingeniería Química
Authors: N. Derka Mariela , Fernández Carina , Bedogni Gabriel A. , B. Okulik Nora
Published: April 2024

La formación de los futuros ingenieros desde un enfoque por competencias es un tema ya instalado desde hace décadas. Si bien existe una profusa bibliografía, son pocos los casos en los que se describe de manera exhaustiva el modo en que se pone en práctica el modelo. En este trabajo se describe el proceso de implementación del desarrollo de competencias articuladas con el desarrollo de capacidades y habilidades desde etapas tempranas del Plan de Estudios de la carrera de Ingeniería Química de la Universidad Nacional del Chaco Austral
Normalized Gaussian Approach to Statistical Modeling of OFDM Signals
Authors: Rudziński Adam
Published: April 2024

This article concerns modeling of statistical properties of OFDM signals with the help of “normalized Gaussian” model, proposed by Kotzer et al. In this paper there is provided an extended formulation of the model, supplemented by an expression for probability density, extending possible applications of the model in theoretical works. Numerical results for verification of the model are provided and a more accurate alternative is suggested.
Subcarrier Gain Based Power Allocation in Multicarrier Systems
Authors: Abd-Elnaby Mohammed , Sedhom Germien G. , El-Samie Fathi E. Abd , Messiha Nagy Wadie , Zhu Xu
Published: April 2024

The Orthogonal Frequency Division Multiplexing (OFDM) transmission is the optimum version of the multicarrier transmission scheme, which has the capability to achieve high data rate. The key issue of OFDM system is the allocation of bits and power over a number of subcarriers. In this paper, a new power allocation algorithm based on subcarrier gain is proposed to maximize the bit rate. For OFDM systems, the Subcarrier Gain Based Power Allocation (SGPA) algorithm is addressed and compared with the standard Greedy Power Allocation (GPA). The authors demonstrate by analysis and simulation that the proposed algorithm reduces the computational complexity and achieves a near optimal performance in maximizing the bit rate over a number of subcarrier.
New Metric for World Wide Web Service Quality
Authors: Uhl Tadeus , Klink Janusz , Bardowski Paweł
Published: April 2024

The main topic of this paper is the quality of the WWW service evaluation. The authors present well-known measurement methods, and present the new “Power” metric for quality, advocating it as a method of assessing the quality of such service. This metric is based on the most important network parameters that affect any assessment of the WWW service, i.e. Web page opening time and download data transfer rate. The new method is easy to implement, fast in operation, and provides stable and repeatable results.
On IPv6 Experimentation in Wireless Mobile Ad Hoc Networks
Authors: Grajzer Monika , Głąbowski Mariusz
Published: April 2024

With the growing interest towards the Internet of Things IPv6-based mobile ad hoc networks (MANETs) become a key enabling technology offering the possibility of automated, unsupervised network configuration and operation. Such a functionality calls for an accurate and reliable testing of the newly proposed solutions, which is challenging due to the dynamic, decentralized and ad hoc nature of MANETs. In this work selected topics are presented on performing IPv6 protocols experimentation in wireless, IPv6-only mobile ad hoc networks – including both simulation – and testbed-based evaluation. Based on the authors experience with the evaluation of the extended IPv6 Neighbor Discovery protocol (ND++) proposed during the course of research, the selection of an opensource simulation environment is presented and a comparison between simulation and emulation experimentation methods is provided. Benefits and drawbacks of both these methodologies for testing IPv6 solutions are depicted. Moreover, the important aspects of topology and mobility considerations are considered. Finally the authors propose a testing approach that would allow for a detailed and accurate evaluation by means of open-source, easily accessible and low-cost methodologies
Bayesian Network Based Fault Tolerance in Distributed Sensor Networks
Authors: Lokesh B. Bhajantri , Nalini N.
Published: April 2024

A Distributed Sensor Network (DSN) consists of a set of sensors that are interconnected by a communication network. DSN is capable of acquiring and processing signals, communicating, and performing simple computational tasks. Such sensors can detect and collect data concerning any sign of node failure, earthquakes, floods and even a terrorist attack. Energy efficiency and fault-tolerance network control are the most important issues in the development of DSNs. In this work, two methods of fault tolerance are proposed: fault detection and recovery to achieve fault tolerance using Bayesian Networks (BNs). Bayesian Network is used to aid reasoning and decision making under uncertainty. The main objective of this work is to provide fault tolerance mechanism which is energy efficient and responsive to network using BNs. It is also used to detect energy depletion of node, link failure between nodes, and packet error in DSN. The proposed model is used to detect faults at node, sink and network level faults ( link failure and packet error). The proposed fault recovery model is used to achieve fault tolerance by adjusting the network of the randomly deployed sensor nodes based on of its probabilities. Finally, the performance parameters for the proposed scheme are evaluated.
Quality Expectations of Mobile Subscribers
Authors: Gilski Przemysław , Stefański Jacek
Published: April 2024

Mobile systems, by nature, have finite resources. Radio spectrum is limited, expensive and shared between many users and services. Mobile broadband networks must support multiple applications of voice, video and data on a single IP-based infrastructure. These converged services each have unique traffic holding and quality requirements. A positive user experience must be obtained through efficient partitioning of the available wireless network resources. The 3 rd Generation Partnership Project (3GPP) has developed a comprehensive Quality of Service (QoS) parameter to address this problem. The regular control of service quality is critical for operators to ensure user Quality of Experience (QoE), establish new business models and monetize services. It enables operators to employ fair-use resource policies and maintain network performance during peak traffic times. Wireless mobile communication is tending towards an integrated system of Internet and telecommunication technologies, where mobile users move freely anytime and everywhere. They desire to communicate with any device using the best service available. In this paper QoS management issues in mobile communication are described. The authors present an insight into subscriber behavior and related factors that affect the QoE of mobile data services.
Prospects and QoS Requirements in 5G Networks
Authors: Tikhvinskiy Valery O. , Bochechka Grigory
Published: April 2024

In this article the requirements to some number of KPI that determine the quality of service (QoS) in 5G networks are formulated. The proposed QoS requirements are based on the analysis of functional requirements to 5G networks and traffic parameters for HD video and massive M2M services, which will be highly demanded in 2020. One of the 5G development paradigms is the network function virtualization (NFV) including cloud radio access and cloud core networks. The authors have proposed the concept of function blocks CQMF and CQCF to control and monitor QoS, which are implemented as part of the 5G network cloud infrastructure.
Holocaust Consciousness and Cold War Violence in Latin America. By Estelle Tarica. Albany: SUNY Press, 2022. 312 pages
Authors: Miller Marilyn
Published: April 2024

Requested Review
Pemberdayaan Potensi Ibu Rumah Tangga dalam Manajemen Sampah Dapur
Authors: Astuti Yuni , Faruq Hilman , Khusna Hikmatul , Anugrah Devi
Published: April 2024

Sampah yang dihasilkan di pulau Pari jauh lebih tinggi saat musim liburan. Sampah organik dari sisa sayur dan makanan laut menimbulkan aroma tidak sedap. Sampah anorganik dari plastik dan sterofoam terlihat di pinggir pantai. Sampah tersebut harus bisa dikurangi dari bagian hulu yaitu rumah warga. Pulau Pari yang dikelilingi oleh laut mengharuskan warganya untuk mengelola sampah dengan bijak agar tidak berakhir di laut. Dengan demikian, warga memerlukan sistem manajemen pengelolaan sampah dapur sebagai solusi yang tepat untuk menanggulangi sampah dari bagian hulu. Dapur warga dijadikan sebagai tempat mengolah makanan katering oleh ibu rumah tangga sebagai pelaku usaha tersebut. Para ibu yang tentunya memiliki waktu luang di rumah perlu diberdayakan potensinya untuk melakukan manajemen sampah dari dapur rumahnya. Kegiatan pelatihan manajemen sampah dapur meliputi identifikasi sampah di rumah dan pemilihan penanganan sampah. Pengabdian ini difokuskan pada pembentukan pola pikir warga tentang pentingnya peran ibu rumah tangga dalam pengurangan dan penanganan sampah di daerah hulu yakni tidak lain di dapur rumahnya sendiri. Para ibu sangat antusias dengan kegiatan pemilahan serta pengolahan kulit udang menjadi bumbu masakan dan cangkang telur menjadi pupuk tanaman.
Pemanfaatan Informasi dan Teknologi Komunikasi di Pesantren Mizanul Ulum
Authors: Indra Dolly , Alwi Erick Irawadi
Published: April 2024

Pesantren Mizanul Ulum mempunyai permasalahan dalam kegiatan pendidikan yaitu model pembelajaran  yang diberikan guru kepada para santri bersifat konvensional dan belum memanfaatkan teknologi komputer. Pengabdian yang kami lakukan bertujuan agar mitra mendapat pengetahuan tentang manfaat informasi dan teknologi komunikasi dengan cara melakukan  sosialisasi  dan pelatihan kepada para guru.  Sosialisasi dan pelatihan  modul pembelajaran terdiri dari pembelajaran Word, Excel, Power Point dan penggunaan Google Forms. Untuk mengetahui hasil dari sosialisasi ini, kami melakukan evaluasi terhadap guru melalui pretest dan posttest dengan jumlah soal sebanyak 30 soal dengan skor maksimal 30. Peserta yang terlibat dalam sosialisasi sebanyak 16 orang guru. Berdasarkan hasil evaluasi diketahui bahwa skor pretest adalah 334 dan skor posttest adalah 414. Rata-rata skor pretest adalah 20,875 dan posttest adalah 25,875 sedangkan skor pretest maksimum adalah 26 dan posttest adalah 28, skor minimum untuk pretest adalah 15 dan posttest adalah 23. Kegiatan sosialisasi yang kami lakukan ini pada Pesantren Mizanul Ulum Sanrobone Kabupaten Takalar mampu meningkatkan pengetahuan para guru.
Distance Lexicographic Discourse: Media Platforms Of Communicative Interaction
Authors: Ivashchenko Victoria
Published: April 2024

The article highlights the problem field of remote lexicographic discourse, the parameters of the vectors of iits description and typological varieties with regard to the terminographic aspect. This problem still does not have relevant coverage in the scientific literature, which gives every reason to propose the author’s own vision of it. The use of the method of problem analysis made it possible to outline the following parameters of the description of remote lexicographic discourse: subject of communication; participants (subjects), channels, vectors of communicative interaction (discursive vectors) and means of communication. System analysis and the method of going from the abstract to the specific made it possible to distinguish in a remote format: on the one hand, intracultural, intercultural (intercultural), transcultural and multicultural lexicographic discourses; on the other – dictionary discourse, dictionary article discourse, terminological and terminographic discourses and lexicographic discourse of terminological schools. Content analysis and the descriptive method highlighted the correlations between the varieties of remote lexicographic discourse and the media platforms of communicative interaction representing them. The use of methods of observation, lexicographic, comparative, systematic analysis and the method of analysis of dictionary definitions made it possible to identify, in accordance with three classification criteria (addressee, communication channel and relation to ethnoculture): the main varieties of lexicographic discourse; a list for each variety with the corresponding platform of mediated (remote) communicative interaction. It has been established that varieties of lexicographic discourse are correlated between the major vectors of communicative interaction. Such a correlation helps to find out on specific examples which media platforms of mediated (distance) communicative interaction as mediators can be used in one or another variety. It is noted that the communicative interaction in the lexicographic discourse involves not only the transfer of information in the format of a dictionary (text), but also the exchange of information about the dictionary in its various forms, including remote.
Sequential Bayesian approach for genetic diversity analysis of the piracanjuba fish (Brycon orbignyanus)
Authors: Da Silva Lima Isabela , Guimarães Brighenti Carla Regina , De Menezes Yazbeck Gabriel
Published: April 2024

In the sequential Bayesian approach, the sample size is not fixed before the experiment; it is determined based on the observations made. The procedure concludes when there is enough information to estimate the parameters, according to a stopping criterion. A parameter of interest in population genetics is the proportion obtained from the allele frequency at one or more loci to verify Hardy-Weinberg equilibrium (HWE). The objective of this study was to assess the occurrence of HWE in a population of piracanjuba fish (Brycon orbignyanus) by estimating the allele proportion and expected genotype proportions using a sequential Bayesian approach. Additionally, a comparison was made with frequentist and Bayesian approaches. Initially, genotypic profiles were analyzed at a microsatellite DNA locus, Bh6, in 49 fish, to determine the frequency of observed alleles and genotypes at the UFSJ Genetic Resources Laboratory. Seven allele classes were observed; thus, under the assumption of sampling independence, the likelihood is multinomial. The estimation of allele and genotype proportions was then carried out using frequentist, Bayesian, and sequential Bayesian approaches. A uniform prior and a cost of 10–3 were considered. The estimates from the three approaches were compared, and it was concluded that the sequential approach proved effective, utilizing only 55.1% of the available data, thereby reducing the sample size and optimizing the procedure. Using a chi-square test at a 5% probability level, it was concluded that the studied sample is in Hardy-Weinberg equilibrium (p-value: 0.9800245).
Sayı temalı bebek kitaplarının incelenmesi
Authors: Bilgen Zehra , Gönen Mübeccel
Published: April 2024

Nitelikli olarak hazırlanmış çocuk kitapları çocukların zihinsel, dil, psikomotor, sosyal-duygusal gelişimini desteklemektedir. Özellikle bebeklik dönemi için hazırlanmış kitaplar bebeklerde el-göz koordinasyonu, küçük kas gelişimi, alıcı ve ifade edici dil gelişimi, kelime kazanımı, taklit yeteneği, dikkat ve zekâ işlevselliği gibi kazanımlar sağlamaktadır. Bu kitaplar aynı zamanda ebeveyn-bebek ilişkisini güçlendirmektedir. Bebeklik döneminde resimli öykü kitapları, bilgi veren kitaplar, alfabe kitapları ve renk, şekil, sayı gibi kavramları içeren sayma kitapları ve kavram kitapları kullanılmaktadır. Bu araştırmanın amacı sayı temasında yazılmış 0-3 yaş bebek kitaplarını incelemektir. Bu amaç ile 50 bebek kitabında fiziksel özellikler, resimleme özellikleri ve içerik özellikleri dikkate alınarak inceleme yapılmıştır. Araştırma nitel araştırma yöntemlerinden doküman analizi yöntemi kullanılarak yürütülmüştür. Verilerin elde edilmesinde araştırmacı tarafından oluşturulan değerlendirme formu ve Deniz ve Gönen (2020) tarafından geliştirilen “Resimli Öykü Kitaplarını Değerlendirme Aracı” kullanılmıştır. Elde edilen bulguların analizinde betimsel analiz tekniğinden yararlanılmıştır. Bulgular yüzde, frekans tabloları ve grafiklerle sunulmuştur. Çalışmadan elde edilen bulgulara göre incelenen kitaplarda cilt türünde genellikle yapıştırma tekniğinin kullanıldığı, mukavva kapak tercih edildiği, kitapların çoğunlukla 6-15 sayfa aralığında ve orta boyut kitaplardan oluştuğu tespit edilmiştir. Sonuçlar bebek kitaplarının resimleme özellikleri bakımından yeterli düzeyde olduğunu ve içerik bakımından ise küçük yaş grubunda sayı temasını kazandırmada etkili birer araç olarak kullanılabileceğini göstermiştir.
Ezop Anlatılarını İçeren Bir Eser: “Letâyifü’l-Hikâyât”
Authors: Alkan Mustafa
Published: April 2024

Köle olarak yaşadığı toplumda, hürlerden daha hür aklıyla asırlar öncesinden günümüze kadar ulaşan hayvan hikâyelerini bizlere miras bırakan Ezop, bu hikâyeleri ile olgun insanda olması gereken özellikler ve olmaması gereken huyları küçük büyük herkesin anlayacağı bir dille anlatmıştır. Bu hikâyeler o kadar ünlenmiştir ki kendinden yaklaşık 2 yüzyıl sonra büyük düşünür Sokrates, 5 yüzyıl sonra Latin ozan Phaedrus ve 21 yüzyıl sonra da La Fontaine bu hikâyeleri nazımla yeniden söylemişlerdir. Ezop’un hikâyeleri geniş bir coğrafyada meydana gelmiştir. Anadolu ve Yunan coğrafyası bu hikâyelerin merkezidir. Ancak onun yaşadığı düşünülen Bâbil ve Mısır da bu hikâyelerin oluştuğu yerlerdendir. İlgili zamanda dünyanın en güçlü devletlerinin olduğu bu geniş coğrafyadan dünyaya yayılan Ezop anlatıları, bütün milletlerin ortak malı olmuş ve birçok dile tercüme edilmiştir. Tahminen 16. yüzyılın sonu 17. yüzyılın başlarında Anadolu’da veya Balkanlar’da Letâyifü’l-Hikâyât adıyla Ezop anlatılarını toplayan bir eser daha vücuda getirilmiştir. Esasını Ezop anlatılarının oluşturduğu bu eserde, Mevlânâ Celâleddîn-i Rûmî’nin Mesnevî’sinden, Ahmed Süheylî’nin Nevâdir-i Süheylî’sinden, Câmiʿü’l-Hikâyât tercümelerinden, Lâmiî’nin Letâif’inden ve Binbir Gece Masalları’ndan da anlatılar mevcuttur. Dili ve imla hususiyetleri itibarıyla bir Eski Anadolu Türkçesi metni olan Letâyifü’l-Hikâyât, hem dili hem de içeriği açısından önem arzetmektedir. Nitekim eserden hareketle Eski Anadolu Türkçesi üzerine yeni değerlendirmeler yapabilmek, Ezop’un biyografisiyle ilgili yeni bilgilere ve yeni Ezop anlatılarına ulaşmak mümkün olacaktır. Bu makalede işbu eser ayrıntılı şekilde tanıtılmaya çalışılacaktır. Ancak eserin dil ve imla hususiyetleri de eklendiğinde çalışmanın bir makale boyutunu çok aşacak olmasından dolayı bu çalışmada eserin tavsifi, içeriği ve yazarı üzerinde durulacak; eserin dil ve imla hususiyetleri bir başka çalışmaya konu edilecektir.
Logic, second edition
Authors: Markov Sergey
Published: April 2024

In the textbook, written in accordance with the Federal State Educational Standard for Higher Education and intended for university students (primarily in the humanities and specialties), logic is considered as a methodological basis and a tool for logically correct thinking. Topics for study include logical rules for dividing the scope of a concept, classification, topics of definitions of terms, logical rules for constructing normative statements, logic of questions and answers, rules and techniques of inference, hypothetico-deductive method, syllogistics, as well as other materials useful for managers , lawyers, doctors, economists.
MANIFESTAÇÕES CLÍNICAS, DIAGNÓSTICO E TRATAMENTO DA HIPERCALCEMIA MALIGNA: UMA REVISÃO NARRATIVA DE LITERATURA
Authors: Albuquerque Maria Gabrielle Pereira De , Pinto Martha Cristyanne De Albuquerque , Silva Weslei Melo da
Published: April 2024

O objetivo deste trabalho é conhecer as manifestações clínicas, diagnóstico e tratamento da hipercalcemia maligna, uma emergência oncológica metabólica com altos índices de mortalidade. A hipercalcemi
IMPORTÂNCIA DE UMA AVALIAÇÃO CLÍNICA CRITERIOSA AO SE ABORDAR PACIENTES EM CRISES HIPERTENSIVAS
Authors: Nishimura Cristiane Yoshie , Medeiros Gustavo Ângelo , Grespan Leonardo Costa , Casagrande Lucas Zuccolotto , Yenikomshian Fernanda Paiva
Published: April 2024

Estudo relacionado à importância de uma avaliação clínica criteriosa em prol de uma melhor abordagem específica ao se deparar com pacientes em hipertensão.
EVOLUÇÃO E MANEJO DA ACINETOBACTER BAUMANNII RESISTENTE A CARBAPENÊMICOS (CRAB) NOS AMBIENTES HOSPITALARES
Authors: Casagrande Lucas Zuccolotto , Medeiros Gustavo Ângelo , Brasil Luiza Vilas Boas Garcia , Yenikomshian Fernanda Paiva , Grespan Leonardo Costa
Published: April 2024

Introdução: a Acinetobacter baumannii é uma bactéria (do tipo cocobacilo) aeróbia Gram-negativa que se configura como um importante patógeno oportunista nos meios hospitalares, que apresenta uma morta
Projeto de Extensão Lei Lucas: Vivências e experiências de acadêmicos de medicina em escola de Colatina
Authors: Oliveira Luma Souza , Monteiro Ana Beatriz Almeida , Reali Marina de Oliveira , Bolzani Laura , Rocha Maria Eduarda Martinelli , Pereira Michelle Viana , Bezerra Mel Pretti , Lorencini Hugo Romais , Januário Pedro Ramos
Published: April 2024

A Lei N°13.722 ou ‘’Projeto de Lei Lucas’’ foi criada com o objetivo de estabelecer a obrigatoriedade da capacitação de profissionais de instituições educacionais em noções de Suporte Básico de Vida,
Métodos Brasileiros de Tomada de Decisões: uma abordagem prática
Authors: Pereira Daniel Augusto de Moura , Santos Marcos dos , Silva Antonio Sergio da , Moreira Henrique Pires , Candido Ana Claudia Luna , Araújo Guilherme Nascimento , Diniz Bruno Pereira , Cavalcanti Neto João , Araújo Jordan Matheus Barbosa , Azevedo Junior Célio Manso de , Kojima Emerson Hissão , Pereira Junior Enderson Luiz , Oliveira Luana de Azevedo de , Gomes Carlos Francisco Simões , Monte Danillo Marcus Marinho do , Costa David de Oliveira
Published: April 2024

A tomada de decisão está presente nas nossas vidas todo dia, o dia todo. Há vezes que tomamos melhores decisões que outras, e isso faz parte do jogo da vida. Mas e se pudéssemos tornar (e tomar) determinadas decisões mais assertivas, baseando-se em modelos matemáticos consistentes para este fim especifico? Neste sentido, este livro, na forma de coletânea, traz uma série de Métodos brasileiros de Tomada de Decisão Multicritério, de maneira a ampliar o conhecimento, e o processo de reflexão, sobre a teoria de Tomada de Decisão Multicritério contemporânea. Constituindo-se em um importante ponto de inflexão nesse processo de sistematização e produção de conhecimentos, esta coletânea tem por objetivo disseminar alguns destes Métodos de Tomada de Decisão Multicritério, a partir de exemplos práticos e reais, de forma ampliar o leque de opções de métodos, na hora que o tomador de decisão precisar.
A natureza da Lógica na obra de Santo Tomás de Aquino
Authors: Araújo Pedro Barbosa
Published: April 2024

Este estudo breve, despretensioso em suas conclusões, tem a finalidade desataviada de esclarecimento das questões mais introdutórias da manualística da Escola, que se referem à ponderação da constituição científica da lógica em geral. Assim, não se tome o incompleto, por introdutório, como acabado, embora nisto que foi feito se manifeste a direção pela qual uma das perspectivas do pensamento lógico vário possa realizar-se em uma colheita veraz.
Importância da educação em saúde no nível de prevenção de doenças e promoção de saúde dos professores de educação física e dos alunos do Ensino de Jovens e Adultos no Pará (EJA)
Authors: Couto Cileide Tavares Borges do
Published: April 2024

A importância da prevenção de doenças e promoção da saúde para alunos da Educação de Jovens e Adultos (EJA) nas aulas de Educação Física é crucial para melhorar o bem-estar e a qualidade de vida dessa população, que muitas vezes enfrenta desafios de saúde específicos devido à idade e ao estilo de vida. O objetivo deste estudo foi verificar a importância da educação em saúde no nível de prevenção de doenças e promoção de saúde dos professores de Educação Física e dos alunos da EJA no estado do Pará. A metodologia utilizada foi um estudo exploratório e de pesquisa de campo, envolvendo 124 docentes e 605 alunos que atuavam e estudavam na modalidade EJA. Os resultados revelaram que a maioria dos estudantes e docentes estava com a vacinação em dia, compreendia conceitos de saúde pública e coletiva e reconhecia a importância da Educação Física para o bem-estar. No entanto, eles enfrentavam dificuldades devido à jornada de trabalho e ao cansaço para uma participação eficaz nas aulas de Educação Física. Isso ressalta a necessidade de políticas e estratégias educacionais que considerem essas limitações, visando aprimorar a promoção da saúde e a prevenção de doenças na EJA.
Not Simply Two Sides of the Same Coin: Target Enhancement and Distractor Suppression Draw on Independent Neural Mechanisms
Authors: Khodayari Natalia , Egeth Howard , courtney susan
Published: April 2024

Enhancement and suppression have traditionally been described as a shared process; enhancing relevant information subsequently suppresses irrelevant information, but there may also exist separable mechanisms. Recent evidence indicates that target enhancement and distractor suppression can be measured separately, using both behavioral and physiological approaches. It is unclear, however, whether the underlying mechanisms are also separable. We used an individual differences approach to investigate whether enhancement and suppression strengths vary independently across individuals, which would provide strong evidence supporting the existence of separate mechanisms. This approach, however, requires dissociable, internally-reliable individual-difference measures. We found reliable enhancement measures for both endogenous cueing effects (Experiment 1) and statistical learning effects (Experiment 2) of target location. Measures of suppression in Experiments 1 and 2 were unreliable. In Experiment 3, we encouraged a single strategy (“singleton-search mode”) by changing the colors and shapes of targets and distractors across trials. We found reliable individual differences in reaction time measures for enhancement and suppression. Critically, these reliable measures did not covary. Experiment 4 largely replicated the results of Experiment 3. Again, individual-difference measures of enhancement and suppression strength did not covary. These results show a clear dissociation: while enhancement yields reliable individual differences across task manipulations, suppression measures are usually unreliable and sensitive to task parameters. When individual-difference measures of both enhancement and suppression are reliable, they do not covary. These results cannot be explained solely by a shared-mechanism account of enhancement and suppression, and instead support the hypothesis that independent enhancement and suppression mechanisms exist.
The impact of cash out availability on online betting behavior
Authors: Szaszi Barnabas , Szecsi Peter , Kolumbán Pál , Kolozsvári Márton , Bognar Miklos , Demetrovics Zsolt , Griffiths Mark , Hung Wei Yue
Published: April 2024

The rise of online sports betting, facilitated by technological innovations such as the cash-out feature, has transformed the gambling landscape. While cash-outs have been suggested to intensify problematic gambling behaviors, empirical studies to date have been correlational, leaving a gap in determining causal evidence. In the present Registered Report, the proposed study will investigate the direct impact of the perceived availability of cash-out feature on various facets of gambling behavior in an online experiment. Hungarian residents with online gambling history will be informed that they will have the chance to gamble real money on sport events. Following random allocation, half of the participants will be told that they will have the option to cash out their bets before the outcome of the sport event is known while the other half will not. The study will compare the proportion of participants placing bets, bet sizes, and bet risks between the two groups. Furthermore, the study will explore the differential effects of the cash-out feature on specific high-risk subgroups. The findings are likely to have significant implications for the design of online betting platforms, contribute to regulatory frameworks, and help in the design of interventions that minimize gambling-related harm.
Infants’ knowledge of individual words: Investigating links between parent report and looking time
Authors: López  Pérez Melanie , Moore Charlotte , Sander-Montant Andrea , Byers-Heinlein Krista
Published: April 2024

Assessing early vocabulary development commonly involves parent report methods and behavioral tasks like looking-while-listening. While both yield reliable aggregate scores, findings are mixed regarding their reliability in measuring infants' knowledge of individual words. Using archival data from 126 monolingual and bilingual 14–31-month-olds, we further examined links across these methods at the word level, while controlling for potentially confounding child-level factors. When data were averaged at the child level, performance on the looking-while-listening task correlated well with parent-reported word production of the same words, as expected. However, mixed-effects model comparisons suggested that at the word level, looking-while-listening performance was significantly predicted by age and total productive vocabulary, but not by parent-reported knowledge of a word once these factors were controlled for. These findings invite careful consideration regarding the adequacy of these two popular methods for capturing children's idiosyncratic knowledge of individual words.
Síntomas neurológicos en disección de aorta: un desafío
Authors: Corrales Morales Cristyan Camilo , Gómez Patiño Jonathan Andrés
Published: April 2024

Introducción: la posibilidad de disección de la aorta se debe considerar cuando aparece dolor torácico o abdominal de instauración súbita, con pico de dolor máximo rápidamente progresivo. Los síntomas neurológicos transitorios o ermanentes al inicio no solo son frecuentes (17-40%) sino que a menudo pueden enmascarar la afección subyacente, en especial ante la ausencia de dolor (5-15%). Objetivo: reportar un paciente con síntomas neurológicos causados por disección de la aorta sin evidencia de lesiones en las neuroimagenes. Presentación del caso: paciente atendido en hospital de mediana complejidad en Caldas, Antioquia, Colombia, por presentar manifestaciones neurológicas sugestivas de accidente cerebro vascular; se remitió a un centro de alta complejidad en Envigado, Colombia, donde se diagnosticó disección aórtica mediante angiotomografía. Discusión y conclusiones: la disección de aorta cursa con un gran espectro clínico y ante síntomas neurológicos no podemos descartarla, pues en caso de trombolizar sería fatal; la disección indolora existe y constituye un reto diagnóstico. Los síntomas neurológicos se asocian con alta mortalidad pero no son contraindicación para la cirugía.
Welding processes in the restoration of industrial and energy facilities
Authors: Zakharova Iryna
Published: April 2024

The research relevance is determined by the constant development and changes in the production environment and technological requirements to ensure increased safety, durability, and efficiency of industrial and energy facilities. The study aims to analyse methods and strategies for improving the efficiency of welding and joint quality control, to achieve greater stability and reliability of energy facilities. The methods used include observation, comparative and descriptive, monitoring, abstraction, and others. The study analysed various welding technologies and their impact on the quality of welded joints. Various methods of calculating welded structures concerning materials and technical requirements were considered. In addition, various methods of quality control of welded joints, including visual inspection and non-destructive testing, were investigated. The study determined that the correct choice of technology, calculations and quality control can improve the strength, reliability, safety, and economic feasibility of welded structures. The studied welding technologies and quality control methods used are more effective for use in specific conditions and there is no general solution. In addition, the proper application of these methods demonstrated that they can significantly reduce the recovery time and increase the overall productivity of the process of restoring industrial and energy facilities. Therefore, the optimal use of welding technologies and quality control methods can significantly improve the efficiency and durability of industrial and energy facilities. The practical significance of the study is to contribute to improving the safety, reliability, and efficiency of the rehabilitation of industrial and energy facilities by improving the quality control procedures for welded joints
Screening of raspberry Rubus idaeus plants of the FSBSO ARHCBAN collection for a marker associated with the RBDV virus resistance trait
Authors: Tarasova E. V. , Kapitova I. A.
Published: April 2024

Viral damage produces a signiﬁcant detrimental eﬀect on raspberry plantations. Raspberry bushy dwarf virus (RBDV) appears particularly harmful, capable to signiﬁcantly reduce raspberry yields. The high prevalence of RBDV is due to its ability to be transmitted by pollen and the absence of visible symptoms on plants during the ﬁrst stages of infection. Breeding of RBDV-resistant varieties can signiﬁcantly reduce the damage caused by RBDV infection. Therefore, a search for genetic markers of RBDV resistance is considered particularly relevant. At present, the Bu gene is identiﬁed with the dominant mode of inheritance associated with the trait of resistance to RBDV. A number of markers, successfully tested on a large sample of foreign raspberry varieties, enable resistant phenotypes to be predicted with high accuracy. However, their testing on Russian varieties is still to be carried out. The paper presents the results of PCR-mediated searching for a diagnostic fragment of the marker rasp_N_gene_1202, associated with the trait of raspberry resistance to RBDV, involving 14 raspberry varieties from the collection of the Federal Horticultural Center. The research was conducted to test the eﬃcacy of the rasp_N_gene_1202 marker in order to identify RBDV-resistant genotypes. The experiment involved 12 Russian varieties and two foreign varieties used as positive control. The work was carried out in the Laboratory of Reproductive Biotechnology of Federal Horticultural Center for Breeding, Agrotechnology and Nursery in 2023. Based on the analysis, a potentially RBDV-resistant variety ‘Arisha’ was identiﬁed. In addition, the diagnostic fragment was detected in moderately resistant and resistant varieties: ‘Gussar’, ‘Orangevoye Chudo’ and ‘Poklon Kazakovu’. However, no diagnostic fragment was detected in the resistant varieties ‘Lavina’ and ‘Medvezhonok’. For this reason, the investigated marker is recommended to be used in combination with other known markers of resistance to RBDV in order to increase the reliability of screening results. No diagnostic DNA fragment was detected on varieties with susceptible phenotype using the tested marker. The obtained data can be used in the selection process to develop new RBDV-resistant varieties.
Evaluation of yield and stability of spring barley mutants of M5-M7 generations
Authors: Tetyannikov N. V.
Published: April 2024

Yield is an important indicator when creating new varieties of crops. Seeking high and stable yields is considered essential in barley breeding. The stability of the studied genotypes was analyzed using various statistical indicators, namely, bᵢ, S²dᵢ, Wi2, σ2i, CV. The experiment was conducted to evaluate yield and stability of barley mutants of M5-M7 generations by parametric statistics. The experiment involved 40 mutants of spring barley belonging to the two-row subsp. distichon L. and six-row subsp. vulgare obtained after mutagenic treatment with phosphemide in two concentrations. The research was carried out in 2020‒2022 on the experimental plot of Federal Horticultural Center for Breeding, Agrotechnology and Nursery (Moscow region, Russia). Phenotypic manifestation of the considered traits and yield varied depending on the year of the experiment. Mutants G3, G5, G7, G16, G19, G20, G22, G23, G24, G27, G29, G33, G34, G40 were characterized by a statistically signiﬁcant excess of control samples on the weight of 1000 grains. The yield of the studied mutants obtained from the Zernogradsky 813 sample was noted in the range of 282.0– 317.9 g/m2, Dz02-129 had 137.2–201.5 g/m2, C.I.10995 had 90.9–282.7 g/m2, a high variability of this trait was observed with the coeﬃcient of variation equal to 71.02 – 152.42%. The highest value of pair correlation of yield was registered with grain weight per plant (r=0.370) and weight of 1000 grains (r=0.371). Strong conjugation was found between bi and CV (r=0.659); S²di and Wi 2 (r=0.885), σ2i (r=0.885); σ2i and Wi 2 (r=1.000). In addition, a close correlation of yield was noted with bᵢ (r=0.459), S²di (r=0.462), Wi2 (r=0.470), σ2 (r=0.470). Mutants G4, G28, G29 were characterized by relatively stable yields. The complex of economic traits combined with high yield potential was possessed by two-row G1, G2, G40 and multi-row G16, G23 to be recommended for use in the breeding process for high productivity.
Resistance of apple clonal rootstocks to the fruit bacterial blight pathogen Erwinia amylovora
Authors: Drenova N. V. , Shamshin I. N. , Dubrovsky M. L. , Maslova M. V. , Ignatov A. N. , Dzhalilov F. S.-U.
Published: April 2024

The review is devoted to resistance of apple clonal rootstocks to bacterial blight of fruit trees considering current data on the biology of its pathogen Erwinia amylovora. The paper provides data on the main known loci of quantitative resistance in Malus species, their genetic markers, and resistance of the main forms of foreign selection. The study collects data on the resistance of Russian clonal rootstocks.