bluuebunny/crossref_metadata_2025 huggingface dataset:
Successful percutaneous paravalvular leak closure followed by transfemoral aortic lotus valve‐in‐valve implantation in a degenerated surgical bioprosthesis
Authors: Nerla Roberto , Cremonesi Alberto , Castriota Fausto
Published: May 2016

Bioprosthesis degeneration is a relevant clinical issue that is increasingly developing with the higher expectancy of life. Its treatment may be further complicated by the presence of paravalvular leaks, which are usually consequence of tissue friability, annular calcification, and infection. The surgical treatment of such complex conditions may be too risky, so percutaneous techniques in selected centers are becoming an attracting option. We report the case of a 65‐year‐old gentleman with a previous aortic valve replacement (Perimount n.25) who was admitted with worsening heart failure and transoesophageal evidence of severe intraprosthetic regurgitation and a large paravalvular leak. Since he was judged at too high risk for surgery, he was treated by a fully percutaneous approach. First, he had his large paravalvular leak closed by implantation of two plugs from both retrograde and anterograde routes (arterial–venous loop created). After one month, he underwent a “valve‐in‐valve” transcatheter aortic valve implantation with a fully repositionable Lotus 23 mm valve, which was able to restore a completely normal aortic valve function and let to a dramatic improvement of his functional status at 6‐month follow‐up (from NYHA IV to NYHA I), when a transthoracic echocardiogram also confirmed the absence of any aortic regurgitation. This case shows how a tailored step‐by‐step fully percutaneous strategy is safe and feasible in high‐risk patients with both bioprosthesis degeneration and large paravalvular leaks. This novel opportunity would need to be better evaluated in properly addressed long‐term clinical studies. © 2016 Wiley Periodicals, Inc.
Fracture of the delivery balloon shaft during balloon‐expandable prosthesis alignment during implantation of an Edwards SAPIEN 3
Authors: Arai Takahide , Hovasse Thomas , Chevalier Bernard
Published: May 2016

The expandable sheath was designed with a lower profile in order to reduce the incidence of vascular complications of transcatheter aortic valve implantation using transfemoral approach. However, once the prosthesis has crossed the sheath, it could be difficult to retrieve it from the body. This is the first case of successful bail‐out in an instance of delivery balloon shaft malfunction subsequent to the crossing of an expandable sheath during implantation of an Edwards SAPIEN 3 prosthesis. © 2016 Wiley Periodicals, Inc.
Transfemoral valve‐in‐valve implantation for degenerated bioprosthetic aortic valves using the new balloon‐expandable Edwards Sapien 3 valve
Authors: Gonska Birgid , Seeger Julia , Rodewald Christoph , Scharnbeck Dominik , Rottbauer Wolfgang , Wöhrle Jochen
Published: May 2016

Background

Surgical aortic bioprosthetic valves deteriorate 10 to 20 years after operation. Valve‐in‐valve implantation with first generation transcatheter aortic valve implantation (TAVI) devices has shown to be feasible. We report a first case series with the new Edwards Sapien 3 valve for transfemoral aortic valve‐in‐valve implantation.

Methods and results

Nine patients underwent valve‐in‐valve‐TAVI with the Edward Sapien 3 valve. Seven patients presented with severe aortic stenosis and two patients with severe aortic insufficiency of surgical aortic bioprosthesis. Procedures were performed in local anaesthesia under fluoroscopic guidance with pre‐procedural 256 multislice computed tomography for procedural planning. In all patients the Edwards Sapien 3 was successfully implanted decreasing the mean echocardiographic gradient from 42 ± 22mmHg to 18 ± 7mmHg (p < 0.01). Device success according to VARC 2 criteria was achieved in 8 out of 9 patients. There was no death, coronary obstruction, use of second valve or need for post‐dilation. Furthermore there were no access‐site complications, no minor or major bleedings or vascular injury. Two patients required pacemaker implantation within the first 7 days after valve‐in‐valve TAVI. Post‐procedural echocardiography demonstrated no or trace aortic regurgitation. Early safety events within 30 days according to VARC‐2 definition occurred in 1 patient.

Conclusions

The Edwards Sapien 3 valve for treatment of failed surgical bioprostheses is feasible and is associated with no relevant post‐procedural aortic regurgitation and a low risk of access site complications. © 2016 Wiley Periodicals, Inc.
Benign pneumoperitoneum in newborns: which abdomen to open and which one to observe?
Authors: Al‐lawama Manar , Al‐Momani Hashem M. , AboKwaik Wael M. , Al‐zaben Khaled R.
Published: May 2016

Key Clinical Message

Benign pneumoperitoneum in newborns is not a rare condition that should be managed conservatively. Neonatologists and surgical teams should work together to avoid unnecessary and potentially risky procedures.
Multiple nodules on the left cheek represented pseudolymphomatous folliculitis
Authors: Horikiri Masaru , Abe Naho , Ueda Kazuki
Published: May 2016

Key Clinical Message

Pseudolymphomatous folliculitis (PLF) is a rare lesion. Sometimes, the clinical appearance is characterized by multiple large, firm violaceous nodules. In cases with multiple lesions, such biopsy should be performed on one lesion, and once PLF is determined, monitoring for the remained tumor is considered to be the best treatment.
Numerical Analysis of Header Structure Improvement in a Plate‐Fin Heat Exchanger
Authors: Zhang Bing , Fan Gang , Yang Jian , Liu Chuangui , Tang Shan
Published: May 2016

In order to improve the flow uniformity in a plate‐fin heat exchanger (PFHE), a modified header structure with a plain baffle inside is proposed. Flow distribution and pressure drop in the header were studied by numerical methods. The results show that the modified header is highly efficient in improving the flow uniformity with negligible pressure drop increase. A performance effectiveness factor was introduced to predict the effects of the modified structure on the performance of the PFHE. Influences of baffle structure parameters on modified structure performances were further discussed. The modified header structure can effectively improve the performance of a PFHE.
Influence of Reaction System Properties on the Energy Saving Potential of the Reactive Dividing‐Wall Column: Separation Properties
Authors: Schröder Moritz , Fieg Georg
Published: May 2016

The reactive dividing‐wall column (RDWC) is an example of extensive process integration. Recently, an energy saving potential of 23 % for the RDWC for an exemplary reaction system has been reported. However, little is known so far whether this magnitude represents a typical value and how the reaction system properties affect the energy saving of the RDWC. Clearly, a prerequisite for the industrial application of this apparatus is a profound understanding of the process and a quick assessment of the energy saving at an early stage of process synthesis. Therefore, the influence of separation properties of the reaction system on the energy saving potential is systematically investigated. Also, the saving mechanisms are analyzed and how they are affected. Heuristics are presented which can be applied easily during the industrial process synthesis.
Iridium(III) Anthraquinone Complexes as Two‐Photon Phosphorescence Probes for Mitochondria Imaging and Tracking under Hypoxia
Authors: Sun Lingli , Chen Yu , Kuang Shi , Li Guanying , Guan Ruilin , Liu Jiangping , Ji Liangnian , Chao Hui
Published: May 2016

In the present study, four mitochondria‐specific and two‐photon phosphorescence iridium(III) complexes, Ir1–Ir4, were developed for mitochondria imaging in hypoxic tumor cells. The iridium(III) complex has two anthraquinone groups that are hypoxia‐sensitive moieties. The phosphorescence of the iridium(III) complex was quenched by the functions of the intramolecular quinone unit, and it was restored through two‐electron bioreduction under hypoxia. When the probes were reduced by reductase to hydroquinone derivative products under hypoxia, a significant enhancement in phosphorescence intensity was observed under one‐ (λ=405 nm) and two‐photon (λ=720 nm) excitation, with a two‐photon absorption cross section of 76–153 GM at λ=720 nm. More importantly, these probes possessed excellent specificity for mitochondria, which allowed imaging and tracking of the mitochondrial morphological changes in a hypoxic environment over a long period of time. Moreover, the probes can visualize hypoxic mitochondria in 3D multicellular spheroids and living zebrafish through two‐photon phosphorescence imaging.
Stabilization of the Columnar Mesophase of Perylenediimide by Racemic Triple Tails
Authors: Pereira de Oliveira Santos Deise M. , Belarmino Cabral Marilia G. , Bentaleb Ahmed , Cristiano Rodrigo , Gallardo Hugo , Durola Fabien , Bock Harald
Published: May 2016

Whereas perylene tetracarboxdiimides derived from amino‐n‐alkanes if at all only show monotropic (thermodynamically unstable) mesogenic self‐assembly, the hexagonal columnar liquid crystalline state can be stabilized over a broad temperature range with doubly branched, doubly racemic alkyl residues. An improved tendency to homeotropic surface orientation is observed, and the orientation of the liquid crystalline domains is maintained upon cycling through the crystalline state at room temperature.
Ultrastrong Chemiluminescence Activity of Nanocarbon Materials after Ozonation and Their Effects on Different Chemiluminescent Systems
Authors: Yang Feng , He Duhong , Wang Meina , Zheng Baozhan , Wu Li , Xiao Dan , Guo Yong
Published: May 2016

Ozonized nanocarbon materials with different dimensionalities, structures, and components exhibited significantly different chemiluminescence (CL) activities. The ozonation time and the weight ratio of hydroxyl carbon nanotubes (d≈8 nm, hyCNTs‐8) and graphene oxide (GO) strongly affected the CL activity of ozonized hybrids. Among GO, hyCNTs‐8, and GO/hyCNTs‐8, the GO/hyCNTs‐8 hybrids exhibited the strongest CL‐enhancing properties toward the luminol/H2O2 system, in contrast to previous reports. This study provides new understanding of the CL activity and CL‐enhancing properties of nanocarbon materials in signal‐enhanced analytical and biomedical fields.
Synthesis and Investigation of 2,6‐Bis(picrylamino)‐3,5‐dinitro‐pyridine (PYX) and Its Salts
Authors: Klapötke Thomas M. , Stierstorfer Jörg , Weyrauther Michael , Witkowski Tomasz G.
Published: May 2016

2,6‐Bis(picrylamino)pyridine (1; pre‐PYX) and 2,6‐bis(picrylamino)‐3,5‐dinitropyridine (2; PYX) were synthesized using an improved literature method. Compounds 1 and 2 were reinvestigated in detail and the X‐ray structures (1: ρ=1.698 g cm−3 at 173 K; 2: ρ=1.757 g cm−3 at 298 K) are given. The reactions of 2 with different bases, such as alkali metal hydroxides (sodium, potassium, rubidium, cesium), and N‐bases (ammonia, hydrazine, hydroxylamine, guanidinium carbonate, aminoguanidine bicarbonate) are reported, as well as metathesis reactions producing energetic salts. Several energetic compounds were synthesized and characterized for the first time using vibrational (IR, Raman) and multinuclear NMR spectroscopy, mass spectrometry, elemental analysis, and DSC. The crystal structures of four energetic salts were determined using low temperature single‐crystal X‐ray diffraction. Heats of formation for the metal‐free species were calculated using the Gaussian 09 software. Detonation parameters were estimated using the EXPLO5 program. The sensitivities towards impact, friction, and electrostatic discharge were also determined.
Effect of Headgroups on Small‐Ion Permeability across Archaea‐Inspired Tetraether Lipid Membranes
Authors: Koyanagi Takaoki , Leriche Geoffray , Yep Alvin , Onofrei David , Holland Gregory P. , Mayer Michael , Yang Jerry
Published: May 2016

This paper examines the effects of four different polar headgroups on small‐ion membrane permeability from liposomes comprised of Archaea‐inspired glycerolmonoalkyl glycerol tetraether (GMGT) lipids. We found that the membrane‐leakage rate across GMGT lipid membranes varied by a factor of ≤1.6 as a function of headgroup structure. However, the leakage rates of small ions across membranes comprised of commercial bilayer‐forming 1‐palmitoyl‐2‐oleoyl‐sn‐glycerol (PO) lipids varied by as much as 32‐fold within the same series of headgroups. These results demonstrate that membrane leakage from GMGT lipids is less influenced by headgroup structure, making it possible to tailor the structure of the polar headgroups on GMGT lipids while retaining predictable leakage properties of membranes comprised of these tethered lipids.
ChemInform Abstract: STABILIZATION OF HEXACOORDINATED IRON(IV) WITH A HIGH SPIN IN AN OXYGEN LATTICE
Authors: DEMAZEAU G. , CHEVREAU N. , FOURNES L. , SOUBEYROUX J.‐L. , TAKEDA Y. , THOMAS M. , POUCHARD M.
Published: May 2016

Für hexakoordiniertes Fe(+lV), das in Oxiden meist eine Konfiguration mit niedrigem Spin hat, wird nach einem Modell für die relative Stabilität der möglichen Grundzustandsterme gezeigt, daß eine Verlängerung der F606 Oktaeder einen Zustand mit hohem Spin (tägdiz ) stabilisieren kann.
ChemInform Abstract: EFFECT OF PARTICLE SIZE ON THE KINETICS OF THE REACTION BETWEEN MAGNESIUM AND ALUMINUM OXIDES
Authors: BERETKA J. , BROWN T.
Published: May 2016

Messungen zu MgO + Al2O3 ‐ MgAl2O4 für "kleine" (1‐3 um) und "große" (ca.
ChemInform Abstract: REACTIONS OF PLATINUM IN OXYGEN‐ AND HYDROGEN‐TREATED PLATINUM/Γ‐ALUMINA CATALYSTS. II. ULTRAVIOLET‐VISIBLE STUDIES, SINTERING OF PLATINUM, AND SOLUBLE PLATINUM
Authors: LIETZ G. , LIESKE H. , SPINDLER H. , HANKE W. , VOELTER J. +
Published: May 2016

Durch UV‐VIS‐Reflexionsspektroskopie an zwischen 100 und 600°C in O2 bzw. bei 500°C in H2 behandelten Pt/y‐AlzOyKatalysatoren werden Existenz und Natur verschiedener oxidierter Pt‐Spezies (s. vorst.
ChemInform Abstract: SYNTHESIS OF TITANIUM DIBORIDE BY HIGH‐DOSE IMPLANTATION OF BORON IONS IN TITANIUM FILMS
Authors: OKAMOTO S. , KAWAI A. , KOBAYASHI K. , TAKATA M. , YAMASHITA T. , YAMASHITA S.
Published: May 2016

Bei 60 kV Beschleunigungsspannung wurden B+‐Ionen bei Raumtemp. in Ti‐Filme (170 oder 300 nm dick) bis zu Konzentrationen von 2.3·1018 Ionen/cm2 (in 50 h bei 2.7 mA B+‐Strom) implantiert.
ChemInform Abstract: CHEMISTRY OF URANIUM IN GLASS‐FORMING MELTS: REDOX INTERACTIONS OF URANIUM WITH CHROMIUM AND IRON IN ALUMINOSILICATES
Authors: SCHREIBER H. D. , BALAZS G. B. , KOZAK S. J.
Published: May 2016

U. a. im Hinblick auf Phänomene bei der "Immobilisierung" von nuklearen Abfallen wurden die gegenseitigen Wechselwirkungen von Uund Cr sowie Uund Fe durch innere Redox‐Reaktionen in Aluminosilicat‐ Glas‐Schmelzen (SiO2‐Al2O3‐CaO‐MgO) durch optische Spektrophotometrie untersucht.
ChemInform Abstract: EFFECT OF METAL IONS IN ORGANIC SYNTHESIS. PART XIII. SELECTIVE REGENERATION OF HYDROXYL AND CARBOXYL GROUPS FROM SOME DERIVATIVES BY COPPER(II) ION‐PROMOTED HYDROLYSIS
Authors: ATTANASI O. , FILIPPONO P. , SERRA‐ZANETTI F.
Published: May 2016

Die Hydroxycarbonsäurederivate (I) und (IV) lassen sich über eine Kupferchlorid‐katalysierte Hydrolyse entweder zweistufig über die acetylierten Säuren (II) und (V) oder einstufig zu den Stammverbindungen (III) und (VI) umsetzen.
ChemInform Abstract: CYCLOADDITION REACTIONS OF BENZOTHIET
Authors: KANAKARAJAN K. , MEIER H.
Published: May 2016

Bei der Photolyse der Diazoverbindung (I) erhält man in tert.‐Butanol den Benzothietester (II), der in den Grundkörper (III) übergeführt wird, der im Gleichgewicht mit dem o‐(′liinoid (IV) steht.
ChemInform Abstract: STEREOPOPULATION CONTROL. VIII. RATE AND EQUILIBRIUM ENHANCEMENT IN THE FORMATION OF HOMOPHTHALIC ANHYDRIDES
Authors: HILLERY P. S. , COHEN L. A.
Published: May 2016

Die Kinetik der säurekatalysierten Cyclisierung (Abhängigkeit der Cyclisierungsgeschwindigkeit von der Säurestärke und ‐l(onzentration) der über (III) bzw. die entsprechend substituierten lndanone auf verschiedenen Wegen erhältlichen Homophthalsäurederivate (VI) (Ausb‐.‐Angaben unvollständig) zu den Anhydriden (VII) in Acetonitril wird untersucht.
ChemInform Abstract: INTRAMOLECULAR ADDITION OF ALKOXYL RADICALS. PART 4. REDUCTIVE CYCLIZATION OF F OLEFINIC HYDROPEROXIDES
Authors: TAILLEZ B. , BERTRAND M. P. , SURZUR J.‐M.
Published: May 2016

Entsprechend dem photolytischen Verhalten läßt sich das Hydroperoxid (IIa) in Gegenwart von Fel, zum Tetrahydrofuran (I) selektiv mit besserer Ausb. cyclisieren; mit TiCl3 ist das Dimer (III) das Hauptprodukt.
ChemInform Abstract: RELATIVE DONOR‐ATOM EFFECTS ON RATES OF ISOMERIZATION OF 3‐BUTENENITRILE CATALYZED BY ANIONS OF THE SAME BASICITY
Authors: BORDWELL F. G. , HUGHES D. L.
Published: May 2016

Die Isomerisierung von 3‐Butennitril (I) zu den Z‐Isomeren (II) erfolgt durch zahlreiche basische Katalysatoren, deren Wirksamkeit in der Reihe Thiophenolat, Phenolat, Sulfonimid und Fluorenyl‐Carbanion abnimmt.
ChemInform Abstract: OXIDATIVE ALKYL‐ AND ARYLAMINOMERCURATION OF PROP‐2‐YNYL ALCOHOLS. SYNTHESIS OF N‐SUBSTITUTED α‐IMINO KETONES, α‐DIIMINES, AND α‐AMINOPROPIONAMIDINES
Authors: BARLUENGA J. , AZNAR F. , LIZ R.
Published: May 2016

Der Propargylalkohol (I) reagiert mit prim. aliphatischen Aminen und Anilinderivaten KzCO3 in Gegenwart von Hg(OAc), zu den Di‐iminen (II).
ChemInform Abstract: INDUCED AND SPONTANEOUS REARRANGEMENT OF TRANS‐2‐ETHOXY‐1‐METHYLCYCLOBUTANE‐R‐1‐CARBOXALDEHYDE TO 2‐ETHOXY‐5‐METHYL‐3,4‐DIHYDRO‐2H‐PYRAN
Authors: MENICAGLI R. , MALANGA C. , LARDICCI L. , PECUNIOSO A.
Published: May 2016

Aus dem Alkohol (I) läßt sich unter den vorliegenden Reaktionsbedingungen der Aldehyd (II) in guter Ausb. erhalten.
ChemInform Abstract: TRANS‐CYCLOALKENES. PART 11. TRANS‐CYCLONONA‐1,2,6‐TRIENE, A TRANSIENT PRECURSOR OF 2,3‐DIVINYLCYCLOPENTENE
Authors: CONNELL A. C. , WHITHAM G. H.
Published: May 2016

Ausgehend von den Epoxiden (I) bzw. (X) werden das Dioxolan (VI) und das Oxathiolan (IX) bzw. das Cyclopropan (XII) synthetisiert.
ChemInform Abstract: SYNTHESIS OF ISOCARYOPHYLLENE BY TITANIUM‐INDUCED KETO ESTER CYCLIZATION
Authors: MCMURRY J. E. , MILLER D. D.
Published: May 2016

Aus dem Dien‐carbonsäureethylester (1) erhält man über eine Keten‐Addition mit Trichloracetylchlorid und anschließende stufenweise Reduktion die Derivate (IIa) bzw. (IIb).
ChemInform Abstract: THE SYNTHESIS OF α‐ACETOXYBENZYLBENZYLNITROSAMINE
Authors: LYLE R. E. , GUNN V. E. , JACOBSON M. K. , LIJINSKY W.
Published: May 2016

Die N‐Nitroso‐Verlaindung (V) wird als Metabolit des nicht mutugenen und nicht carcinogenen N‐Nitroso‐dibenzylamins hergestellt.
ChemInform Abstract: ACETYLATIONS OF STRONGLY BASIC AND NUCLEOPHILIC ENOLATE ANIONS WITH N‐METHOXY‐N‐METHYLACETAMIDE
Authors: OSTER T. A. , HARRIS T. M.
Published: May 2016

N‐Methoxy‐Nanethylaeetamid (II) wird zur Acetylierung von Enolaten aliphatischer Polyketone eingesetzt.
ChemInform Abstract: SYNTHESIS OF 2‐ARYL‐3‐ARYLSULFONYL‐6‐METHYLCHROMONES AS PCA INHIBITORS
Authors: JADHAV K. P. , INGLE D. B.
Published: May 2016

Aus den Phenacylehloriden (I) und den Thiophenolen (II) werden die Thioether (IIIa) hergestellt, die zu den Sulfonen (IIIb) oxidiert werden.
ChemInform Abstract: SYNTHESES OF NEW DERIVATIVES OF 2,2‐DIALKYLFUROCHROMENES
Authors: ZAWADOWSKI T. , MAZUR A. , ULIASZ A.
Published: May 2016

Die Chromene ( l) reagieren mit dem Ester (II) über die Stufe der Ester (III) zu den Carbonsäurext, welche zu den Furochromenen (IV) cyclisiert werden.
ChemInform Abstract: FACILE PREPARATION OF OPTICALLY PURE (3S)‐ AND (3R)‐1,2,3,4‐TETRAHYDROISOQUINOLINE‐3‐CARBOXYLIC ACID
Authors: HAYASHI K. , OZAKI Y. , NUNAMI K. , YONEDA N.
Published: May 2016

Unter den im Formelschema angegebenen Bedingungen lassen sich aus optisch aktivem Phenylalanin (I) optisch reine Tetrahydroisochinolincarbonsäurederivate (III) bzw. (IV) herstellen.
ChemInform Abstract: SYNTHESIS AND PROPERTIES OF A NEW CLASS OF PYRIDODIPYRIMIDINES, 8‐ALKOXYPYRIDO(2,3‐D:6,5‐D′)DIPYRIMIDINE‐2,4,6(3H,10H,7H)‐TRIONES
Authors: YONEDA F. , NAGAMATSU T. , TAKAMOTO M.
Published: May 2016

Aus den Alkylaminotiraeilen (I) erhält man mit den Orthoestern (II) die neuen Heteroeyelen (III), die weiter zu den Derivaten (IV) und (VI) umgewandelt werden.
ChemInform Abstract: INTRAMOLECULAR AND INTERMOLECULAR REACTIONS OF ALKENYLSILYL RADICALS
Authors: CHATGILIALOGLU C. , WOYNAR H. , INGOLD K. U. , DAVIES A. G.
Published: May 2016

Die Radikale, die bei der Photolyse von Di‐tert.‐butylperoxid und einer Anzahl von Alkenyldi methylsilanen wie (I), (III) und (V) entstehen, werden ESR‐spektroskopisch untersucht.
ChemInform Abstract: PREPARATION OF 4‐SUBSTITUTED ARSABENZENES
Authors: ASHE A. J. III , ABU‐ORABI S. T.
Published: May 2016

I ,4‐Pentadiin (I) reagiert mit Dibutylzinnhydrid (II) zu einem Addukt (IIIa), das über das Anion in die Substitutionsprodukte (IIIb)‐(IIIg) umgewandelt wird, Mit Arsentribromid entstehen die entsprechenden Arsabenzole (IV).
ChemInform Abstract: CHALCOGENOLATES. 119. STUDIES ON N‐NITROCARBAMATES, O‐ETHYL ESTER OF N‐NITROCARBAMIC ACID, AND SALTS OF THIS ESTER. ATTEMPTS TO PREPARE N‐NITRODITHIOCARBAMATES
Authors: GATTOW G. , KNOTH W. K.
Published: May 2016

(I) wurde in Anlehnung an eine Literaturmethode durch Umsetzen des Ammoniumsalzes ( aus Carbamidsäure‐O‐ethylester, konz. H2SO4 und Salpetersäureethylester und Einleiten von NH3, 32% Ausb.) mit Schwefelsäure dargestellt und durch Elektronen‐ und IR‐Spektren charakterisiert.
ChemInform Abstract: CALCIUM AFFINITY OF COORDINATED DIPHOSPHONATE LIGANDS. SINGLE‐CRYSTAL STRUCTURE OF ((EN)2CO(O2P(OH)CH2P(OH)O2))CLO4.H2O. IMPLICATIONS FOR THE CHEMISTRY OF TECHNETIUM‐99M‐DIPHOSPHONATE SKELETAL IMAGING AGENTS
Authors: JURISSON S. S. , BENEDICT J. J. , ELDER R. C. , WHITTLE R. , DEUTSCH E.
Published: May 2016

H2O. Implications for the Chemistry of Technetium‐99m‐Diphosphonate Skeletal lmaging Agents.
ChemInform Abstract: SYNTHESIS AND CRYSTAL STRUCTURE OF MERCURY‐BRIDGED TRANSITION‐METAL CLUSTERS: HG(RU3(CO)9(C2‐TERT‐BU))2 AND ((C2‐TERT‐BU)RU3(CO)9HGMO(η‐C5H5)(CO)3)
Authors: ERMER S. , KING K. , HARDCASTLE K. I. , ROSENBERG E. , MANOTTI LANFREDI A. M. , TIRIPICCHIO A. , TIRIPICCHIO CAMELLINI M.
Published: May 2016

Durch Reaktion der in einer Eintopfreaktion mit höherer Ausb. erlangten, bereits bekannten Produkte (IV) mit den Verbindungen (V) bzw. (VII) werden die Titelverbindungen (VI) und (VIII) synthetisiert.
ChemInform Abstract: CONDUCTIVITY OF COMMERCIAL ZIRCONIA ELECTROLYTES. I. IONIC AND N‐TYPE CONDUCTIVITIES OF 15 M/O CSZ AT OXYGEN PRESSURES OF SOLID CHROMIUM‐SOLID CHROMIUM OXIDE MIXTURE
Authors: GOZZI D. , CIGNINI P. L. , STAMPA E.
Published: May 2016

Mit galvanischen Zellen (I) wurden für CSZ‐Festkörperelektrolyte (kommerzielles, durch 15 mol‐% CaO stabilisiertes Zr02) die Leitfähigkeiten bez. Aktivierungsenergien bei 1195‐19 l 7 K und Abhängigkeit vom Gleichgewichts‐O,‐Partialdruck der Cr(s)‐ Cr3O3 (s)‐Elektroden untersucht.
ChemInform Abstract: INTERFACE BETWEEN SOLID ELECTRODE AND SOLID ELECTROLYTE ‐ A STUDY OF THE LITHIUM/LITHIUM IODIDE(ALUMINUM OXIDE) SOLID‐ELECTROLYTE SYSTEM
Authors: JOW T. R. , LIANG C. C.
Published: May 2016

In der galvanischen Festkörper‐Zelle (I) wird bei der Entladung am Li/LiI(Al2O3)‐Kontakt Li zu Li" oxidiert.
ChemInform Abstract: A NEW OXONIOBATE(V) WITH A LAYER‐TYPE STRUCTURE: RUBIDIUM OXONIOBATE (RB4NB6O17)
Authors: SERAFIN M. , HOPPE R.
Published: May 2016

Farblose, wasserklare quaderförmige Kristalle von Rb4Nb6O" (orthorhombisch, Z=4, Pnma) wurden erstmals durch Tempern (1100°C, 14 d) inniger Gemische von RbOoßs und Nb2O, erhalten.
ChemInform Abstract: SYNTHESIS AND STRUCTURAL DETERMINATION OF A NEW TWO‐DIMENSIONAL COMPOUND: P2NB4S21
Authors: BREC R. , EVAIN M. , GRENOUILLEAU P. , ROUXEL J.
Published: May 2016

Die aus den Elementen in stöchiometrischen Verhältnissen bei 600°C in 8 Tagen erhaltenen dunkelroten nadelförmigen Kristalle zeigen monokline Symmetrie, Raumgruppe C2/c, Z=4.
ChemInform Abstract: PREPARATION AND PROPERTIES OF COMPLEX CARBONATES OF HEXAVALENT ACTINIDES
Authors: MARQUART R. , HOFFMANN G. , WEIGEL F.
Published: May 2016

Komplexe Carbonate ′(I) wurden durch Zusatz von festem (NH4), CO3 zu Lösungen mit An(VI)‐Ionen hergestellt.
ChemInform Abstract: MONOLAYER AND BILAYER VESICLE MEMBRANES FROM P‐PHENYLENEDIAMINE DERIVATIVES
Authors: FUHRHOP J.‐H. , BARTSCH H.
Published: May 2016

Nach Ultraschalleinwirkung auf wäßrige Suspensionen der Aminosäuren (Ia) und (Ib) bei pH 5.5 unter Luftabschluß entstehen instabile vesikuläre Lösungen bzw. Vesikel‐ Cluster, wobei die einzelnen Vesikel aus (Ib) erheblich kleiner sind als die aus (Ia).
ChemInform Abstract: MECHANISM OF OXIDATION OF TRIALKYLAMINES BY FERRICYANIDE IN AQUEOUS SOLUTION
Authors: BURROWS E. P. , ROSENBLATT D. H.
Published: May 2016

Die Kinetik der Oxidation der Aminoverbindungen (I)‐(III) durch das Hexacyanoferrat?ll) (IV) wird im pH‐Bereich zwischen 3,7 und 13,4 untersucht.
ChemInform Abstract: RADICAL REACTIONS OF CARBOHYDRATES. PART 4. ELECTRON SPIN RESONANCE STUDIES OF RADICAL‐INDUCED OXIDATION OF SOME ALDOPENTOSES, SUCROSE, AND COMPOUNDS CONTAINING FURANOSE RINGS
Authors: GILBERT B. C. , KING D. M. , THOMAS C. B.
Published: May 2016

Während OH‐Radikale z.B. aus Tetrahydrofurfurylalkohol oder Isopropylidenderivaten der Glucofuranose bevorzugt H‐Atome abtrennen, die dem O‐Atom im Furanring benachbart sind, reagieren sie mit Saccharose, einer DNA‐Modellsubstanz, selektiv mit dem Furanosyl‐, aber nicht selektiv mit dem Pyranosylteil des Moleküls.
ChemInform Abstract: THE OXIDATIVE COUPLING OF PHENOLS. PART 10. THE ROLE OF STERIC EFFECTS IN THE E FORMATION OF CARBON‐OXYGEN COUPLED PRODUCTS
Authors: ARMSTRONG D. R. , CAMERON C. , NONHEBEL D. C. , PERKINS P. G.
Published: May 2016

Während die Oxidative Kupplung von (Ib) hauptsächlich den Ether (IIIb) neben wenig (IIb) ergibt, liefert (Ia) unter diesen Bedingungen ausschließlich (IIa).
ChemInform Abstract: REACTION OF AMINO ALCOHOLS WITH BUTADIENE CATALYZED BY PALLADIUM COMPLEXES
Authors: GROULT A. , GUY A.
Published: May 2016

Die Alkyl‐ bzw. Arylaminoethanole (I) reagieren mit 1,3‐Butadien (II) im Molverhältnis 1 22 in Gegenwart von Pd(acac),/PPh3 fast ausschließlich zu den Octadienylaminoethanolen (III).
ChemInform Abstract: NITROCARBONS. 3. SYNTHESIS OF DECANITROBIPHENYL
Authors: NIELSEN A. T. , NORRIS W. P. , ATKINS R. L. , VUONO W. R.
Published: May 2016

In einer rein präparativen Arbeit wird über die im Formelschema aufgeführten Stufen die Decanitro‐Verbindung (V) hergestellt.
ChemInform Abstract: DEHYDRATION OF 1‐SUBSTITUTED SECONDARY AND TERTIARY BICYCLO(3.3.1)NONAN‐9‐OLS. A SUBSTITUENT‐DRIVEN REARRANGEMENT TO 4‐SUBSTITUTED AND/OR ANGULARL SUBSTITUTED HEXAHYDROINDENES
Authors: BALATA F. , DELLO JACONO A. R. , GAMBACORTA A.
Published: May 2016

Aus den Bicyclononanolen (I) bzw. (VII) erhält man bei der Behandlung mit p‐Toluolsulfonsäure verschiedene Folgeprodukte (II)‐(VI) bzw. (VIII)‐(XI) in den angegebenen Mengen.
ChemInform Abstract: SOME NEW DERIVATIVES OF 4‐PYRIDINECARBOXYLIC ACID. PART I. PRODUCTS OF REACTIONS WITH AROMATIC AMINES
Authors: SAMULA K. , ROSTAFINSKA B.
Published: May 2016

Kondensation des Pyridincarbonsäureesters (I) mit den Aminen (II) in DMF im Molverhältnis I : 1 liefert die Amide (III).
ChemInform Abstract: PREPARATION OF 2‐AMINO‐4(3H)‐OXOPYRIMIDO(5,4‐B)(1,4)THIAZINES (5‐THIAPTERINS) AND THEIR EVALUATION AS COFACTORS FOR PHENYLALANINE HYDROXYLASE
Authors: HENRIE R. N. II , LAZARUS R. A. , BENKOVIC S. J.
Published: May 2016

Das Diaminoinercaptopyrimidinon (I) reagiert mit Bromacetophenon (II) zum Thiapterin (III), das mit überschüssigem Natriumborhydrid zur Dihydroverbindung (IV) reduziert wird.
ChemInform Abstract: ADDITION COMPOUNDS OF ALKALI‐METAL HYDRIDES. 23. PREPARATION OF POTASSIUM TRIISOPROPOXYBOROHYDRIDE IN IMPROVED PURITY
Authors: BROWN H. C. , NAZER B. , SIKORSKI J. A.
Published: May 2016

Die 1′ B‐NMR‐spektroskopisch ermittelte Verunreinigung, vermutlich K[B(OiPr)4 ], in kommerziellem oder in aus KH Vund B(0iPr)3 in THF bei Raumtemp. dargestelltem K[BH(OiPr)3] kann durch Rückflußkochen in THF über KH entfernt werden.
ChemInform Abstract: REACTIONS OF TRIALKYLSILYL TRIFLUOROMETHANESULFONATES. II. SYNTHESIS OF O‐ALKYL‐O‐(TRIALKYLSILYL)KETENE ACETALS AND 2‐(TRIALKYLSILYL)CARBOXYLATES
Authors: EMDE H. , SIMCHEN G.
Published: May 2016

Durch Silylierung mit den Trialkylsilyltriflaten ( II) in Gegenwart von Triethylamin werden aus den Carbonsäureestern (la, b) die Ketenacetale (IIIa, b) erhalten, während die Ester (Ic‐e) Gemische der Ketenacetale (IIIc‐e) mit den am α‐C‐Atom silylierten Estern (IVc‐e) bilden.
ChemInform Abstract: DIAMIDOFLUOROPHOSPHAZO COMPOUNDS
Authors: MARCHENKO A. P. , KOVENYA V. A. , PINCHUK A. M.
Published: May 2016

Beim Einleiten von Fluorwasserstoff in eine Lösung der Diamido‐chlor‐phosphazoalkane (I) entstehen über Zwischenstufen wie (II) die Diamido‐fluor‐phosphazo‐alkane (III).
ChemInform Abstract: ELECTRON‐TRANSFER PROCESSES AND ELECTRODEPOSITION INVOLVING THE IRON HEXACYANOFERRATES STUDIED VOLTAMMETRICALLY
Authors: GONCALVES R. M. C. , KELLAWI H. , ROSSEINSKY D. R.
Published: May 2016

Voltammetrische Untersuchungen zeigen, daß sich durch zwei Elektroreduktionen aus Lösungen von Fe" und Hexacyanoferrat?ll) ein Niederschlag von Eisen(III)‐hexacyanoferrat(II) ("Preußischblau") bildet, der vermutlich über einen l:l‐Komplex entsteht.
ChemInform Abstract: 2‐Amino‐4‐picoline N‐Oxide Complexes Formed from Various Copper(II) Salts.
Authors: WEST D. X.
Published: May 2016

Die Titelverbindungen (I)‐(IV) wurden nach einer beschriebenen Methode dargestellt (keine Ausb.‐Angaben) und zur Strukturzuordnung IR‐, elektronen‐ und ESR‐ spektroskopisch untersucht.
ChemInform Abstract: Formation of Osmium Nitrile Complexes and Phosphinimine Complexes from N‐ Aroylphosphinimines.
Authors: GOEDEN G. V. , HAYMORE B. L.
Published: May 2016

Os(III)‐nitril‐Komplexe des Typs (II) werden durch die Umsetzung des Tetrachloro‐Os(IV)‐Komplexes (I) mit aromatischen Nitrilen oder N‐Aroylphosphiniminen erhalten.
ChemInform Abstract: Platinum Metal Complexes of the Methoxyphenylstibines Ph3‐nSb(o‐MeOC6H4)n(n = 1, 2, 3), o‐Me2SbC6H4OMe and of Me2Sb(CH22)O(CH2)2O(CH2)2StMe2.
Authors: HIGGINS S. J. , LEVASON W. , MCCULLOUGH F. P. , SHEIKH B.
Published: May 2016

o‐Methoxy‐phenyl‐dimethylstibin reagiert mit Na‐tetrachloropalladat, K‐tetrachloroplatinat, Rh‐ oder Ir‐trichloridtrihydrat unter Bildung der cis‐Bis‐[ligand]‐Komplexe (I) (L: L1),dem fac‐Rh‐Komplex (III) bzw. dem mer‐Ir‐Komplex (IVb) (L: L1).
ChemInform Abstract: PALLADIUM(II) AND PLATINUM(II) DICHLORO COMPLEXES CONTAINING DIAMINE‐ESTRONE DERIVATIVES
Authors: FERNANDEZ G. J. M. , RUBIO‐ARROYO M. F. , RUBIO‐POO C. , DE LA PENA A.
Published: May 2016

Die Liganden in einer 2:1‐Benzol/Dioxan‐Mischung reagieren mit Bis‐ [benzonitrill‐metallchloriden in Benzol bei 55°C in 5 h zu den Titelkomplexen (I) und (l1), die durch IR‐Daten und Leitfähigkeitsmessungen charakterisiert wurden.
ChemInform Abstract: SYNTHESIS, PROTON NMR AND ELECTRONIC ABSORPTION SPECTRA, AND HALOCHROMIC PROPERTIES OF BIS(1,2‐DIMETHYL‐3‐INDOLIZINYL)HETARYLMETHANE DYES
Authors: NAEF R.
Published: May 2016

Aus den Hetarylaldehyden (I) und 1,Z‐Dimethylindolizin‐perchlorat (I l) werden die im Titel genannten Verbindungen auf dem angegebenen Weg hergestellt.
ChemInform Abstract: NORRISOLIDE, A NOVEL DITERPENE FROM THE DORID NUDIBRANCH CHROMODORIS NORRISI
Authors: HOCHLOWSKI J. E. , FAULKNER D. J. , MATSUMOTO G. K. , CLARDY J.
Published: May 2016

Das Diterpen Norrisolid (I) wird aus der im Titel genannten Spezies isoliert.
ChemInform Abstract: REACTION PATHWAY IN THE BASE TRANSFORMATION OF 2,4‐O‐BENZYLIDENE‐1,6‐DI‐O‐P‐TOLYLSULFONYL‐D‐GLUCITOL INTO 1,3‐ANHYDRO‐2,4‐O‐BENZYLIDENE‐D‐GLUCITOL
Authors: SINCLAIR H. B.
Published: May 2016

Aus dem Ditosylat (I) wird über die Stufen des Epoxids (II) und des Tricycltxs (III) das Oxetan (IV) erhalten.
ChemInform Abstract: SYNTHESIS AND ANTITUMOR ACTIVITY OF 2‐β‐D‐RIBOFURANOSYLSELENAZOLE‐4‐CARBOXAMIDE AND RELATED DERIVATIVES
Authors: SRIVASTAVA P. C. , ROBINS R. K.
Published: May 2016

Aus dem Nitril (I) erhält man das Selenoamid (II), das über die Verbindung (IV) in das gewünschte Selenazol (VI) umgewandelt wird.
ChemInform Abstract: THE HYPERSTOICHIOMETRIC ZIRCONIUM‐MANGANESE‐IRON (ZRMN1+XFE1+Y)‐HYDROGEN SYSTEM. II. HYSTERESIS EFFECT
Authors: SINHA V. K. , WALLACE W. E.
Published: May 2016

Isothermen der Abhängigkeit des Hg‐Absorptionsdruckes von der Zusammensetzung (g‐Atom H/mol der Legierung) wurden bei 23 ‐200°C für ZrMn,‐" Feu, ‐H, und ZrMn,‐" Fem, ‐H, bestimmt.
ChemInform Abstract: REACTIONS OF FLUORINE ATOMS WITH WATER, HYDROGEN PEROXIDE, AND AMMONIA
Authors: WALTHER C.‐D. , WAGNER H. GG.
Published: May 2016

Die zur Erzeugung der Radikale OH, HO2 und NH2 verwendeten Reaktionen (A, B, C) wurden mit einem Überschuß an F‐Atomen in‐ einem thermostatierbaren Strömungsystem untersucht.
ChemInform Abstract: DIFFUSE REFLECTANCE INFRARED AND PHOTOLUMINESCENCE SPECTRA OF SURFACE VANADYL GROUPS. DIRECT EVIDENCE FOR CHANGE OF BOND STRENGTH AND ELECTRONIC STRUCTURE OF METAL‐OXYGEN BOND UPON SUPPORTING OXIDE
Authors: IWAMOTO M. , FURUKAWA H. , MATSUKAMI K. , TAKENAKA T. , KAGAWA S.
Published: May 2016

Am Beispiel der V=O‐Doppelbindungen in V2O5 wird demonstriert, daß die M‐O‐Bindungen von (katalytisch aktiven) Metalloxiden vomTrägermaterial beeinfluß werden.
ChemInform Abstract: THE 12‐S‐CIS CONFORMATIONALLY LOCKED 11‐CIS‐RETINOIDS: A DELINEATION OF THE THERMAL REQUIREMENTS FOR (1,5)‐SIGMATROPIC SHIFTS AND ELECTROCYCLIZATIONS IN THE VITAMIN A SERIES AND NOVEL SPECTRAL PROPERTIES
Authors: CHANDRARATNA R. A. S. , BAYERQUE A. L. , OKAMURA W. H.
Published: May 2016

Ausgehend von den Komponenten (Ia) (Darstellung beschrieben), (II) und (IV) wird das Vinylalkenol (Va) synthetisiert, dessen thermolytische Umlagerungsreaktion die isomeren Produkte (VIIIa) + (VIIIb) + (IXa) sowie die tetracyclische Verbindung (VI) liefert.
ChemInform Abstract: KINETIC APPLICATIONS OF ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY. 41. DIETHOXYPHOSPHONYL RADICALS
Authors: ANPO M. , SUTCLIFFE R. , INGOLD K. U.
Published: May 2016

Untersucht werden die Geschwindigkeitskonstanten der H‐Abspaltung aus Organohalogeniden durch das Titel‐Radikal.
ChemInform Abstract: REACTIONS OF COMPLEXING LIGANDS. XXIV. SYNTHESIS OF NAPHTHOL DERIVATIVES FROM M CARBONYL‐CARBENE COMPLEXES AND ALKYNES: REGIOSELECTIVE INCORPORATION OF THE ALKYNE TO THE NAPHTHALENE FRAMEWORK
Authors: DOETZ K.‐H. + , MUEHLEMEIER J. + , SCHUBERT U. , ORAMA O.
Published: May 2016

Pentacarbonyl‐(methoxyphenylcarben)‐chrom (I) reagiert mit verschiedenen Alkinen wie (II) oder (IV) zu Tricarbonyl‐(4‐methoxy‐l ‐naphthol)‐ Chrom‐Komplexen (III),(V) bzw. (VI).
ChemInform Abstract: DERIVATIVES OF 5‐HYDROXYMETHYLFURFURAL. I. SYNTHESIS OF DI‐ AND TERFURAN DERIVATIVES
Authors: EL‐HAJJ T. , MARTIN J.‐C. , DESCOTES G.
Published: May 2016

Das aus Pentosen erhaltene Furfural (I) kann mit Divinylsulfon (H) in ein Diketon (l′ll) übergeführt werden, das mit Schwefelsäure/Acetanhydrid das Terfuran (IV) ergibt.
ChemInform Abstract: BENZO(B)THIOPHENE DERIVATIVES. XXVI. 5‐METHOXY‐6‐CHLORO‐3‐β‐ACETAMIDOETHYLBENZO(B)THIOPHENE, A BLOCKED ANALOG OF MELATONIN
Authors: CAMPAIGNE E. , SMITH H. A. JUN. , SANDHU J. S. , KIM C. S.
Published: May 2016

Das Acetophenon (Ia) wird als Ketal (IIa) zu (IIb) chloriert und zum Acetophenon (Ib) verseift‐, das über das Rhodanin (III) zur Mercapto‐en‐carbonsäure (IV) führt und zu (V) cyclisiert werden kann.
ChemInform Abstract: 4‐(2‐DIPROPYLAMINOETHYL)‐7‐METHOXYINDOLE
Authors: CANNON J. G. , LUKSZO J. , MAX G. A.
Published: May 2016

Die lndolderivate (V)‐(IX) werden nach dem im Formelschema gezeigten Weg synthetisiert.
ChemInform Abstract: A NOVEL SYNTHESIS OF FUSED IMIDAZO(5,1‐C)‐1,2,4‐TRIAZOLES
Authors: ABD ALLAH S. O. , EAD H. A. , KASSAB N. A. , ZAYED M. M.
Published: May 2016

Aus den Arylmethylen‐ Verbindungen (IIIa) und (IIIb) des Thiohydantoins erhält man mit Benzylamin (II) die Kondensationsprodukte (I), mit Phenylhydrazin (IV) die Hydrazone (V), die mit Aldehyden (VI) zu den Imidazo‐triazolen (VII) führen.
ChemInform Abstract: THREE SYNTHESES OF 3,8‐DIMETHYL‐1H‐PYRANO(4,3‐B)BENZOPYRAN‐10‐ONE, A MODEL FOR THE SYNTHESIS OF THE FUNGAL METABOLITE, FULVIC ACID
Authors: DEAN F. M. , AL‐SATTAR M. , SMITH D. A.
Published: May 2016

Durch Chlormethylierung von (Ia) zu (Ib) und anschließende Umsetzung mit Methanol/Base erhält man (lc), das zu einem Gemisch aus (II) und (IIIa) umgesetzt wird.
ChemInform Abstract: 1‐AZAADAMANTANES FROM PHLOROGLUCINOLS
Authors: RISCH N.
Published: May 2016

Mit Hexamethylentetramin (II) reagieren die Trihydroxybenzole (I) zu den 1‐Aza‐adamantanen (III).
ChemInform Abstract: PYRIMIDINES. 6. 6‐TRIFLUOROMETHYL CHLOROPYRIMIDINES AND RELATED COMPOUNDS
Authors: GERSHON H. , GREFIG A. T. , SCALA A. A.
Published: May 2016

Das 2‐Thio‐pyrimidin (Ia) wird zu (Ib) methyliert und dann in die Derivate (IIa) bis (IIc) übergeführt.
ChemInform Abstract: THE SYNTHESIS OF TETRAKISDEHYDROTETRAAZAANNULENES. TETRAMETHYL(36)‐ AND ‐(48)ANNULENES AND THEIR BENZOANNELATED DERIVATIVES
Authors: OJIMA J. , KIRITA M. , MUROSAWA Y. , NAKADA T.
Published: May 2016

Die durch Reaktion entsprechender Aldehyde mit Acetylenendgruppen und Hydrazinsulfat erhaltenen unsymm. bzw. symm. Azine (III) und (VIII) bzw. (V) und (X) ergeben nach oxidativer Kupplung die Titelverbinl17 dungen (XI) und (XII) sowie (XIV) und (XV) bzw. (XIII) und (XVI).
ChemInform Abstract: Condensed 1,3,5‐Triazepines. Part 5. The Synthesis of Pyrazolo[1,5‐a][1,3,5]benzotriazepines.
Authors: AGAI B. , HORNYAK G. , LEMPERT K.
Published: May 2016

Durch Reaktion der Arylhydrazine (I) mit Aminocrotonsäurenitril (II) erhält man die Hydrazone (III), die sauer in ethanolischer Lösung zu den Pyrazolen (IV) cyclisiert werden.
ChemInform Abstract: A NEW APPROACH TO THE FORMATION OF PHOSPHORUS‐PHOSPHORUS DOUBLE BONDS
Authors: COWLEY A. H. , KILDUFF J. E. , MEHROTRA S. K. , NORMAN N. C. , PAKULSKI M.
Published: May 2016

Das bis‐silylierte Phosphonigsäuredichlorid (I) reagiert mit (II) zum Diphosphen (III), das auch aus (V) mit (II) statt der erwarteten Verbindung (IV) erhalten wird.
ChemInform Abstract: NEW TITANOCENE DERIVATIVES WITH AMINOTHIOPHENOLATE LIGANDS
Authors: KOEPF H. , GRABOSKI S. , BLOCK B.
Published: May 2016

Titanocendichlorid (I) reagiert mit den Alkaliaminothiophenolaten (II) in Tetrahydrofuran oder Benzol bei Raumtemperatur je nach den Stöchiometrieverhältnissen der Reaktanten unter Substitution eines oder beider Chlorid‐Liganden zu den entsprechenden Mono‐ oder Bis‐(aminothiophenolatol‐Komplexen (III) bzw. (IV).
ChemInform Abstract: OXIDATIVE IMINATION OF TIN(II) COMPOUNDS BY ORGANIC AZIDES
Authors: KHMARUK A. M. , PINCHUK A. M.
Published: May 2016

Die Umsetzung der Arylsulfonylazide (I) mit der Zinnverbindung (II) verläuft trotz der Anwesenheit der voluminösen Substituenten am Zinnatom unter Dimerisierung zu dem Derivat (III).
ChemInform Abstract: HYDROCARBON FUNCTIONALIZATION BY THE (IODOSYLBENZENE)MANGANESE(IV) PORPHYRIN COMPLEXES FROM THE (TETRAPHENYLPORPHINATO)MANGANESE(III)‐IODOSYLBENZENE CATALYTIC HYDROCARBON OXIDATION SYSTEM. MECHANISM AND REACTION CHEMISTRY
Authors: SMEGAL J. A. , HILL C. L.
Published: May 2016

Die Mn‐ Porphyrin‐Komplexe (I) und (II) reagieren mit prim., sek. und tert. Alkanen in relativ inerten Lösungsmitteln wie CH2Cl" Chlor‐ oder Brombenzol bei 25°C zu funktionalisierten Produkten in guten Ausbeuten.
ChemInform Abstract: SYNTHETIC STUDIES ON THE TAXANE DITERPENES. UTILITY OF THE INTRAMOLECULAR DIELS‐ALDER REACTION FOR A SINGLE‐STEP, STEREOCONTROLLED SYNTHESIS OF A TAXANE MODEL SYSTEM
Authors: SAKAN K. , CRAVEN B. M.
Published: May 2016

Als Vorstufe der gewünschten Verbindung (VII) wird über das Kondensationsprodukt (IV) des Cyclohexadiens (H) mit Acrylsäuremethylester das Tetraen (VI) dargestellt, das sich beim Erhitzen in Gegenwart von Trimethylborat (zur Unterdrückung der Bildung von Nebenprodukten) durch eine intramolekulare Diels‐Alder‐Reaktion cyclisiert.
ChemInform Abstract: BICYCLIC α‐AMINO ACIDS. IV: SYNTHESIS OF 3‐(1‐TETRALINYL)‐ AND 3‐(5,6,7,8‐TETRAHYDRO‐5‐QUINOLINYL)ALANINE
Authors: REIMANN E. , DAMMERTZ W.
Published: May 2016

Durch Umsetzung von α‐Tetralon (Ia) bzw. dem Aza‐ Analogen (Ib) mit Diethylcyanomethylphosphonat ist das E/Z‐Gemisch (llD/(IV) erhältlich, das nach Trennung zum gesättigten Nitril (V) und anschließend zum Aldehyd (VI) umgesetzt wird.
ChemInform Abstract: SYNTHESIS OF POTENTIAL ANTINEOPLASTIC ANTHRACENEDIONE DERIVATIVES. I. SUGAR DERIVATIVES
Authors: NAKAMURA K. , ASAI T. , HARA T. , MINORIKAWA N. , SUAMI T.
Published: May 2016

Aus dem Anthracendion (I) wird die Verbindung (II) mit geschützten Aminogruppen hergestellt.
ChemInform Abstract: SYNTHESIS OF ADIPOSIN‐1, α‐GLUCOSIDE HYDROLASE INHIBITOR
Authors: OGAWA S. , IWASAWA Y. , TOYOKUNI T. , SUAMI T.
Published: May 2016

Die mit Schutzgruppen versehene Anhydro‐Maltose (I) wird mit Natriummethylat in das Epoxid (II) umgewandelt und mit dem Di‐O‐isopropyliden‐valienamin (III) zu einem Gemisch von Trisacchariden umgesetzt, aus dem sich nach Abspaltung der Schutzgruppen das freie Pseudo‐trisaccharid Adiposin‐l (IV) isolieren läßt. (Opt.
ChemInform Abstract: ERGOT ALKALOIDS. LXIX. (5R,8S,10R)‐6‐ALKYL‐8‐ERGOLINECARBOXYLIC ACIDS AND SOME OF THEIR DERIVATIVES
Authors: CERNY A. , ZIKAN V. , VLCKOVA D. , BENES J. , HOLUBEK J. , REZABEK K. , AUSKOVA M. , KREPELKA J.
Published: May 2016

Aus dem Ergolin (Ia) werden über die Stufen (Ib) und (Ic) die 6‐Alkylester (Id) und (Ie) hergestellt, die in die entsprechenden Carbonsäuren und Hydrazide übergeführt werden.
Prediagnostic aspirin use and mortality in women with stage I to III breast cancer: A cohort study in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Authors: Bradley Marie C. , Black Amanda , Freedman Andrew N. , Barron Thomas I.
Published: May 2016

BACKGROUND

There is a body of evidence indicating that aspirin may reduce the risk of cancer mortality. However, to the authors' knowledge, the optimal exposure timing and mechanism of action remain unclear. In the current study, the authors investigated associations between prediagnostic aspirin use and breast cancer‐specific mortality in a US population.

METHODS

Postmenopausal women diagnosed with stage I to III breast cancer (1993‐2009) were identified (2925 women with a total of 18,073 person‐years) from the National Cancer Institute's Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Prediagnostic aspirin use (1274 women) was identified from study questionnaires. Multivariate Cox proportional hazards models were used to estimate hazard ratios (HRs) with 95% confidence intervals (95% CIs) for associations between aspirin use and breast cancer‐specific mortality. Effect modification by lymph node status was evaluated.

RESULTS

Prediagnostic aspirin use was not found to be associated with lower breast cancer‐specific mortality (HR, 0.95; 95% CI, 0.68‐1.31 [P = .74]). In analyses stratified by lymph node status, aspirin use was found to be associated with lower breast cancer‐specific mortality among women with lymph node‐negative tumors (HR, 0.54; 95% CI, 0.32‐0.93 [P = 0.02]), but not those with lymph node‐positive tumors (HR, 1.41; 95% CI, 0.92‐2.16 [P = 0.11]). Tests for interaction were found to be statistically significant (P for interaction =.006). No association was noted between aspirin use and lymph node status.

CONCLUSIONS

Prediagnostic aspirin use was not found to be associated with a reduction in breast cancer‐specific mortality overall. However, effect modification by lymph node status was observed and mortality was found to be reduced by approximately one‐half among aspirin users with lymph node‐negative disease. This represents a clinically significant reduction in breast cancer mortality. These findings contribute to the understanding of aspirin's mechanism of action in breast cancer. However, further etiologic research to understand this association is warranted. Cancer 2016;122:2067–75. © 2016 American Cancer Society.
Investigating the Effects of Particulate Matter on House Dust Mite and Ovalbumin Allergic Airway Inflammation in Mice
Authors: Castañeda Alejandro R. , Pinkerton Kent E.
Published: May 2016

Particulate matter (PM), a component of air pollution, has been shown to enhance allergen‐mediated airway hypersensitivity and inflammation. Surprisingly, exposure to PM during the sensitization to allergen is sufficient to produce immunological changes that result in heightened inflammatory effects upon future allergen exposures (challenge) in the absence of PM. This suggests that PM has the ability to modulate the allergic immune response, thereby acting as an adjuvant by enhancing the immunological memory formed during the adaptive immune response; however, the mechanisms through which this occurs remain elusive. Establishing a reproducible animal model to study the PM‐mediated immunotoxicological effects that enhance allergy, may provide insights to understand how air pollution activates the immune system and thereby modulates the pathophysiology of asthma. The basic protocol can be used to study various characteristics of air pollution, such as PM size, source, or chemical composition, to help elucidate how such features may affect the allergic response in a mouse model of asthma. Using a BALB/c model of acute exposure (14 days), mice are first sensitized with allergen and PM, and then subsequently challenged with allergen only. The endpoints of this basic protocol include the assessment of inflammation via cells recovered from broncho‐alveolar lavage (BAL), histopathological analysis, gene expression profiles, and protein quantification of inflammatory markers. © 2016 by John Wiley & Sons, Inc.
Thermal noise analysis of switched‐capacitor integrators with correlated double sampling
Authors: Im Saemin , Park Sang‐Gyu
Published: May 2016

Correlated double‐sampling (CDS) is widely used to suppress the effect of flicker noise in switched‐capacitor (SC) circuits. Once the flicker noise is suppressed by CDS, the noise of the SC circuits is ultimately determined by the thermal noise. In this work, we develop a method to calculate the thermal noise in SC integrators as functions of a variety of circuit parameters such as capacitor size and switch resistance; this methodology is then applied to a CDS integrator as well as a conventional integrator. We found that for the CDS integration scheme, in order to avoid significantly increasing the noise power of the integrator, the size of the CDS capacitor should be comparable to that of the sampling capacitor. We also found that if the CDS capacitor is sufficiently large, the noise power of a CDS integrator is almost the same as that of a conventional integrator with the same sampling capacitor size. These findings are explained based on the bandwidth of the transfer functions. Copyright © 2016 John Wiley & Sons, Ltd.
Statistical Model of Dielectronic Recombination of Heavy Ions in Plasmas
Authors: Leontyev D. S. , Lisitsa V. S.
Published: May 2016

Calculation of the total dielectronic recombination (DR) rates was done in the frame of a statistical model of atoms. The model is based on the idea of collective excitations of atomic electrons with the local plasma frequency, which depends on atomic electrons density distribution. The electron density is described in a frame of the Thomas‐Fermi model of atoms. Simple scaling laws for temperature Te and nuclear charge Z dependences follow from the statistical model of DR. Results of the statistical model were compared with other numerical data following detailed level‐by‐level computations for different multielectron ions. The specific attention is paid to Ni‐like ion sequences of different chemical elements in order to check the Z ‐dependence of DR rates. A comparison with numerical data of Flexible Atomic Code (FAC) is presented for tungsten ions. The reasonable correspondence between the statistical model and the detailed numerical data is demonstrated. The application of the statistical model provides very simple and fast calculations of the DR rates useful in modern plasma modelling. (© 2016 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)