bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating the effect of apple pomac silage as fodder source on performance and residues of its toxins in milk and some rumen fermentation in Mahabadi lactation goats in early lactation period
Authors: Gharehbagh A. G. , Pirmohammadi R. , Alijoo Y. A. , Behroozyar H. K.
Published: April 2020

The aim of this study was to evaluate effect of apple pomace silage as fodder source on performance and residues of its toxins in milk and some rumen fermentation in Mahabadi lactation goats in early lactation period. There was no significant difference within treatments apple pomace mixed silage had no effect on dairy goat’s average daily feed intake. There were no significant differences about pH changes between treatments. The protozoa population tended to decrease and ammonia nitrogen has increased significantly in different treatments (P≤0.05). According to the increase of volatile fatty acids production, the proportion of acetatenot differed even though that of Propionate and iso-butyrate increased but none significantly. The molar ratios of acetate and propionate and iso-butyratein the goats rumen containing apple pomace was differed in respect to the availability for fermentation by rumen microflora. In regard to this information, the inclusion of apple pomace silage in experimental goat’s diet was associated with a slight lower rumen pH, higher concentration of acetate and propionate and total volatile fatty acids in rumen. The potential value of byproducts in animal feeding and better dry matter and organic matter digestibilitydepends on their nutritive characteristics. But the livestock producers are responsible for ensuring that the animals and products that they market do not contain unacceptable chemical residues. Anyone intending to feed waste materials to ruminant animals such as cattle, sheep and goatsor to pigs must ensure that it is free of prohibited or restricted substances.
Prevalence and risk factors for depression among antenatal women during third trimester of pregnancy in a tertiary care centre
Authors: P. Reena Ravindran , Jayaprakash Megha , M. Amrutha , K. Ambujam
Published: April 2020

Background: With the rising incidence of Maternal deaths due to suicide as evident from reports of Kerala state confidential review of maternal deaths, there is a felt need for screening for depression in study antenatal population. Though there have been various screening tools used, a simplified tool validated in study population was not used in study antenatal women till now. The objective of this study was to estimate the prevalence of depression among antenatal women admitted in the department of obstetrics and gynecology, Government Medical College, Thrissur and also to study the risk factors associated with depression in the study population.Methods: A questionnaire based cross sectional observational study was conducted among 100 antenatal women in their third trimester. PHQ-9 questionnaire was used to screen for depression and the information regarding risk factors was collected from the patient, her caregivers and from clinical records. Data analysis was done using EPI-INFO/SPSS software.Results: Prevalence of depression among hospitalized mothers: 53%. Most cases (70%) had: mild depression (PHQ Score: 5-9). Only very few (2%) of them had severe depression (PHQ score: more than 20). 9% had: moderately severe depression (PHQ score: 15-19). 19% had: moderate depression (PHQ score: 10-14). Statistically significant risk factors identified in this study were fetal gender preference, anxiety about labour process, anxiety about labour pain, anxiety about making the baby a part of their life and anxiety about baby’s health.Conclusions: The prevalence of depression among hospitalized mothers using PHQ-9 scale is high (53%). Screening for depression was found to be feasible and can be made a part of routine antenatal care so that appropriate interventions can be provided to improve maternal mental health and thereby prevent the maternal mortality occurring due to suicides.
İnsan Odaklı Aydınlatmanın Kent Ölçeğinde İrdelenmesi: Çanakkale
Authors: ALKAN Yavuz
Published: April 2020

Amaç: Çalışmanın amacı, Çanakkale kent parklarında aydınlatma birimlerinin yeterlilikleri ve kullanıcı memnuniyeti üzerine odaklanmıştır.Materyal ve Yöntem: Bu çalışmada insan odaklı aydınlatma disiplini çerçevesinde Çanakkale kent ölçeğinde aydınlatma birimleri ele alınmış; insan ölçeği ile ilişkilendirilmeye çalışılmış; anket uygulaması ile de bireyin memnuniyetine etkileri ışığın; ışıklandırma şiddeti, tayfı, miktarı, konumlanması, etki alanı, gün ışığına benzeme oranı gibi öğeler kapsamında araştırılmıştır. Kullanıcı memnuniyetine yönelik veriler SPSS 15. istatistiki analiz yöntemi ile belirlenmiştir. Aydınlatma birimlerinin kalite, miktar, estetik ve işlevsellik açısından sahip olduğu nitelik ve nicelikler yerinde incelemelerle tespit edilmiştir.Bulgular: Bu çalışma, elde edilen verilerden, odak noktasında insan faktörü olan aydınlatma tasarımlarının kent planlamasında yeri ve önemine vurgu yaparak, kent planlamalarında daha çok yer alması gerektiğini; dolayısıyla aydınlatmanın kentsel gönencin artırılmasında doğrudan etkili olabileceğini öne çıkarmaktadır. Çalışma kapsamında Özgürlük Parkı, Golf Bahçesi, Halk Bahçesi ve 500.Yıl Parkı aydınlatma kapasitesi ve insan odaklı tasarı açısından verildiği sırayla fazladan aza doğru öneme sahip olduğu bulgusuna ulaşılmıştır. İstatistiksel analiz sonucunda bağımlı değişken kullanıcı memnuniyeti ile aydınlatma ölçütlerinden oluşan bağımsız değişkenler arasında anlamlı ilişkilerin olduğu da bulgular arasında yer almaktadır.Sonuç: Çalışmanın sonucu olarak Çanakkale'de aydınlatma unsurlarının yeterli kapsam ve niteliklerde insan odaklı tasarlanmadığı ortaya çıkmıştır.
L’optimisation des programmes de sélection
Authors: PHOCAS F.
Published: April 2020

La finalité d’un programme de sélection est de générer du progrès génétique dans les générations animales futures afin de répondreaux besoins alimentaires, nutritionnels, sociaux et environnementaux de demain. Les travaux pionniers en optimisation technique etéconomique des programmes de sélection des années 1970 à 1990 sont décrits dans cette synthèse. Maintenant, il s’agit d’accroître àla fois le nombre de caractères inclus dans les objectifs de sélection et la valeur prédictive des critères de sélection et des valeurs génétiquesprédites pour permettre le choix le plus fiable possible dès le plus jeune âge, de reproducteurs améliorateurs parmi les candidatsà la sélection. A ce titre, la sélection génomique est une véritable révolution dans la gestion des populations apparue dans la premièredécennie du 21ème siècle. L’organisation des programmes de sélection doit être revue en profondeur : la poursuite duraisonnement classique, c'est-à-dire la forte diffusion d’un petit nombre de reproducteurs élites est extrêmement dangereuse en termesde maintien d’une diversité génétique raisonnable au sein des populations animales, notamment si l’on raccourcit dans le mêmetemps l’intervalle entre générations en supprimant l’étape de contrôle sur descendance chez les bovins. Les objectifs de sélection doiventêtre adaptés, pour intégrer les nouveaux caractères, au fur et à mesure qu’ils seront évalués. Ce point est d’autant plus critiqueque des évolutions défavorables ont été constatées sur divers caractères fonctionnels et que la génétique devra s’intégrer dans uneplus grande diversité de systèmes de production pour répondre aux attentes sociétales.
Utilisation de la sélection génomique chez les bovins laitiers
Authors: GUILLAUME F. , BOICHARD D. , DUCROCQ V. , FRITZ S.
Published: April 2020

Au sein des espéces d’élevage, c’est sans nul doute dans le secteur des bovins latiers que l’expérience de l’usage des outils moléculairesà des fins de sélection est la plus longue. Bien qu’aujourd’hui la plupart des grands pays d’élevage laitier réalisent des évaluationsgénomiques, l’introduction de ces outils ne se fait pas de façon uniforme. Ceci peut s’expliquer par des conditions de mise en oeuvredifférentes entre pays. Nous dressons ici un panorama de l’utilisation qui est faite des outils de la sélection génomique en bovinslaitiers au niveau international.
Perspectives d’application de la sélection génomique dans les schémas d’amélioration génétique porcins
Authors: TRIBOUT T.
Published: April 2020

L’évaluation génomique est une nouvelle méthode d’estimation de la valeur génétique des animaux d’élevage qui est en train de révolutionnerl’organisation des schémas d’amélioration génétique bovins laitiers. La récente disponibilité d’une puce porcine de 60 000marqueurs SNP permet d’envisager la mise en place de cette méthodologie chez le porc. Dans cette espèce, les perspectives les plusintéressantes de l’évaluation génomique semblent être la possibilité d’améliorer les populations pour des caractères non mesurablesen routine, d’augmenter la précision des valeurs génétiques estimées, et de sélectionner les individus de l’étage de sélection pour leurvaleur en croisement et en milieu de production. Les coûts de mise en oeuvre d’une sélection génomique chez le porc seraient élevés,en raison principalement de la taille des populations de référence nécessaires à une évaluation précise, du nombre élevé de candidatsà génotyper, et de la variété des populations et lignées sélectionnées. Le partage de ressources entre Organisations de Sélection et lerecours aux techniques d’imputation génotypiques permettraient de maîtriser ces coûts.
Predictive models and under-five mortality determinants in Ethiopia: evidence from the 2016 Ethiopian Demographic and Health Survey
Authors: Bitew Fikrewold , Nyarko Samuel H. , Potter Lloyd , Sparks Corey S.
Published: April 2020

Background: There is a dearth of literature on predictive models estimating under-five mortality risk in Ethiopia. In this study, we develop a spatial map and predictive models to predict the sociodemographic determinants of under-five mortality in Ethiopia. Methods: The study data were drawn from the 2016 Ethiopian Demographic and Health Survey. We used three predictive models to predict under-five mortality within this sample. The three techniques are random forests, logistic regression, and k-nearest neighbors For each model, measures of model accuracy and Receiver Operating Characteristic curves are used to evaluate the predictive power of each model. Results: There are considerable regional variations in under-five mortality rates in Ethiopia. The under-five mortality prediction ability was found to be moderate to low for the models considered, with the random forest model showing the best performance. Maternal age at birth, sex of a child, previous birth interval, water source, health facility delivery services, antenatal and post-natal care checkups, breastfeeding behavior and household size have been found to be significantly associated with under-five mortality in Ethiopia. Conclusions: The random forest machine learning algorithm produces a higher predictive power for under-five mortality risk factors for the study sample. There is a need to improve the quality and access to health care services to enhance childhood survival chances in the country.
Analysis of transcriptomic changes in bovine endometrial stromal cells treated with lipopolysaccharide
Authors: Ding Xuefen , Lv Haimiao , Deng Lixin , Hu Wenju , Peng Zhan , Yan Chenbo , Yang Dexin , Tong Chao , wang Xinzhuang
Published: April 2020

Background: Endometritis adversely affects the ability of cattle to reproduce, and significantly reduces milk production. Consequently, it has great influence on the economic value of dairy cows. The endometrium is mainly composed of epithelial and stromal cells and they produce the first immune response to invading pathogens. Epithelial cells are the first cellular barrier through which bacteria enter the uterine endometrium. However, most of the epithelial cells are disrupted and stromal cells are exposed to an inflammatory environment when endometritis occurs, especially postpartum. A loss of the protective epithelium allows bacteria or toxins to access the underlying stromal cells. The activation of Toll-like receptor（TLRs）on stromal cells induces increased production of cytokines. Understanding the genome-wide characterization of the bovine endometritis will be beneficial for prevention and treatment of endometritis. In this study, whole-transcriptomic gene changes in bovine stromal cells treated with LPS were compared with those treated with PBS (control group) and were analyzed by RNA sequencing (RNA-seq). This was done in a cell culture model in vitro.Results: Compared with the control group, a total of 366 differentially expressed genes (DEGs) were identified in LPS-induced group (234 upregulated and 132 downregulated genes), with an adjusted P-value＜0.05 by DESeq. Gene ontology (GO) enrichment analysis revealed DEGs were most enriched in lymphocyte activation, interleukin-1 receptor binding, regulation of cell activation, and lymphocyte-activated interleukin-12 production. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed DEGs were most enriched in TNF signaling pathway, Toll-like receptor signaling pathway, cytokine-cytokine receptor interaction, nucleotide-binding oligomerization domain-like (NOD-like) receptor signaling pathway, NF-κB signaling pathway, and chemokine signaling pathway.Conclusion: The results of this study unraveled bovine endometrial stromal cells affected with LPS transcriptome profile alterations，which may have a significant effect on the treatment inflammation by comprehending molecular mechanisms and authenticating unique genes related to endometritis.
NCAM and attached polysialic acid affect behaviors of breast epithelial cells through differential signaling pathways
Authors: Cao Lin , Wang Xin , Yang Juhong , Guo Jia , Li Xiang , Yang Xiaomin , Tan Zengqi , Guan Feng
Published: April 2020

Background
Neural cell adhesion molecule (NCAM), a common mammalian cell surface glycoprotein, is the major substrate of polysialic acid (polySia). Polysialylated NCAM occurs in many types of cancer, but rarely in normal adult tissues. Epithelial-mesenchymal transition (EMT) is an important process contributing to tumor metastasis. The functional role of NCAM hypersialylation in EMT is unclear.
Method
Expression of NCAM and polysialylated NCAM in breast cancer progression were evaluated by western blot (WB), immunohistochemistry, semi-quantitative PCR and immunoprecipitation (IP). Overexpression of NCAM-140 and ST8SiaII were performed to assess the functional role of NCAM hypersialylation by liposome transfection. Cell proliferation ability was investigated with MTT assay. Transwell and wound closure assay were conducted to evaluate cell migratory ability. Phagokinetic gold sol assay and cell adhesion assay were performed to assess cell motility ability and cell adhesion ability, respectively. Furthermore, WB and IP were used to reveal the activated signaling pathway.
Results
The present study indicates that NCAM and attached polysialic acid affect behaviors of breast epithelial cells through differential signaling pathways, based on the following observations: (i) NCAM and polysialylated NCAM were aberrantly regulated in breast cancer cells; (ii) NCAM and polysialylated NCAM expression were upregulated in normal breast epithelial cells undergoing EMT; (iii) NCAM overexpression induced EMT in breast epithelial cells; (iv) NCAM promoted cell proliferation and migration through activation of a β-catenin/slug signaling pathway; (v) modification of polySia attached to NCAM inhibited cell adhesion and promoted cell motility through activation of an EGFR/STAT3 pathway.
Conclusion
This study demonstrates that NCAM and polysialylated NCAM facilitate different signaling pathway and affect different cell behaviors. Switching between the NCAM-mediated pathways appeared to depend on polySia decoration.
microRNA-21 upregulates YAP by inhibiting transcription factor RUNX1 to regulate immunosuppressive ability of myeloid-derived suppressor cells in lung cancer
Authors: Meng Guangping , Wei Jinying , Wang Yanjun , Qu Danhua , Zhang Jie
Published: April 2020

Background Lung cancer is one of the most frequently fatal cancers. The microRNA-21 (miR-21) has a known oncogenic function on immune cells in tumors, but its biological role and clinical significance in immunosuppression of lung cancer remains largely enigmatic. Our study aims to explore the role and molecular mechanisms of miR-21 in lung cancer. Methods We observed that miR-21 and YAP were highly expressed, while RUNX1 was poorly expressed in lung cancer tissues and cell lines. The loss- and gain- function approaches were performed to determine the roles of miR-21, RUNX1 or YAP in the immunosuppressive ability of myeloid-derived suppressor cells (MDSCs) in lung cancer. Results MiR-21 inhibition, YAP knockdown or RUNX1 overexpression reduced the proportion of MDSCs in lung cancer tissue and peripheral blood, but increased the proportion of T helper (Th) and CTL. Furthermore, miR-21 inhibition, YAP knockdown or RUNX1 overexpression increased apoptosis of MDSCs, more cells at G0/G1 phase, fewer cells at G2/M phase, but reduced IL-10, TGF-β and GM-CSF levels. The effect of miR-21 and RUNX1 on tumor growth was verified by xenograft tumors in nude mice. Conclusions Taken together, miR-21 upregulates YAP expression by inhibiting RUNX1 and consequently promotes the immunosuppressive ability of MDSCs against lung cancer.
Рост объемных эпитаксиальных пленок AlN полуполярной ориентации на подложках Si (001) и гибридных подложках SiC/Si (001)
Authors: Кукушкин С.А. , Осипов А.В. , Редьков А.В. , Шарофидинов Ш.Ш.
Published: April 2020

Abstract The possibility of growing bulk (more than 7 μm thick) epitaxial semipolar AlN films on Si(001) and hybrid SiC/Si(001) substrates without cracks has been investigated. It is found that an AlN layer grown on the Si substrate is extended, whereas an AlN layer grown on the hybrid SiC/Si substrate is compressed. The limiting (critical) thickness of the semipolar AlN layer on the Si(001) substrate is determined to be ~7.5 μm. When the film thickness exceeds this value, an ensemble of cracks is formed in the film, leading to its total cracking and exfoliation from the substrate. The semipolar epitaxial AlN films with a thickness of more than 40 μm are grown on hybrid SiC/Si substrates without cracking and exfoliation from the substrate.
The origin and formation of socio-economic relations between Russia and Armenia
Authors: Safarian Valery Vitalevich
Published: April 2020

This article, dedicated to the 190th anniversary of the accession of Western Armenia to the Russian Empire, is aimed at drawing attention to the monumentality of this historical event, characterized by the comprehensive development of Russian-Armenian relations. It focuses on such important aspects as the possibility of compromises in the process of allied associations for the benefit of further cooperation, the construction of joint socio-economic steps, the development of a common cultural heritage, defense, etc. An important part of the article is the consideration of the evolution of Russian-Armenian relations up to the beginning of the 21st century including the main milestones and events that influenced the relations under consideration are highlighted.
Hubungan Dukungan Keluarga Dengan Kepatuhan Pasien Kanker Payudara Menjalani Kemoterapi Di Rsud Dr. H. Abdul Moeloek
Authors: Setiawati Octa Reni , Roza Ghina Efrilia
Published: April 2020

Breast cancer is the most common type of cancer experienced by women in the world and is also the type of cancer that is the leading cause of death in women. One type of treatment that can be used in the treatment of breast cancer is chemotherapy. Chemotherapy is a type of treatment to kill or slow down the growth of cancer cells which requires a long period of time, where in this treatment required compliance. Adherence in chemotherapy can be influenced by several factors, one of which is family support. To find out the relationship between family support and breast cancer patient's compliance undergoing chemotherapy at RSUD Dr. H. Abdul Moeloek Lampung Province. Analytical observational research with a retrospective approach. The sampling technique is done by accidental sampling. Obtained data from 120 samples that filled out family support questionnaires and medical records of patients undergoing chemotherapy at RSUD Dr. H. Abdul Moeloek, Lampung Province, which has good family support of 101 people (84.2%) and 108 patients (90.0%) are obedient to chemotherapy. Kendall-tau test results obtained a significance value of 0.000 which indicates that there is a significant relationship between family support and breast cancer patients adherence undergoing chemotherapy. There is a significant relationship between family support and breast cancer patient compliance undergoing chemotherapy with a correlation coefficient of 0.607 and a significance value of 0.000.
Hubungan antara Efikasi Diri dan Regulasi Diri dengan Prestasi Akademik pada Mahasiswa Program Studi Ilmu Al-Qur’an dan Tafsir UIN Raden Intan Lampung
Authors: Agustina Fitri , Malay Muhammad Nursalim
Published: April 2020

Academic achievement is an achievement achieved by someone in the academic field. This achievement can be achieved if a person has confidence and has the ability to manage him/her-self. This study aims to determine the relationship between self-efficacy and self-regulation with academic achievement in 57 students of the Al-Qur'an Science study program and the interpretation of UIN Raden Intan Lampung. The sampling technique used is sampling total then analyzed by multiple regression analysis techniques. The results of this research analysis explain that there is a relationship between self-efficacy and self-regulation with academic achievement in students of the study program of the Qur'an and the interpretation of UIN Raden Intan Lampung with a correlation coefficient (R) = 0,859 and F = 76,136 with p = 0,000. Then, there is a significant relationship between self-efficacy and academic achievement in students, the results of the analysis obtained are with the value of rx1y = 0,817 with p = 0,000. Furthermore, there is a relationship between self-regulation and academic achievement in students seen from the results of calculations obtained by the value rx2y = 0,854 with p = 0,000.
Does Banking in Indonesia tend to be Concentrated?
Authors: Maharani Novita Kusuma , Sumardi Sumardi , Salisu Auwal
Published: April 2020

The banking in Indonesia has undergone several changes in the market structure that ultimately impacts the prevailing policies and regulations. This study aims to examine the impact of changes in the banking market structure identified through the level of market concentration in the banking environment and examine the factors that influence the level of concentration of the banking market from 2005 to 2016. The study also examined the impact of changes in banking structure during the global crisis. The measurement of banking concentration used in this study is the Herfindahl-Hirschman Index (HHI). Furthermore, the influential factors consist of: (1) Bank specification, including bank size (Size), credit risk (NPL), profitability (ROE), banksoundness(CAR),(2)Market specification,namely the number of standingbank (NUM), and (3) Global crisis. The study used GLS (Generalized Least Square) method to detect autocorrelation on each variable.The results show that banks in Indonesia tended to have a low level of market concentration. The results are also in accordance with the SCP paradigm which states that banks tend to generate high profits when the level of banking market concentration is high.Keywords : Market Concentration, Competition, Dual-Banking, Bank Specification, Market Specification, Global Crisis.
Cosmological Dimensions in The Teachings of The Naqshabandi Sufi Order
Authors: Burhanuddin Nunu , Syihab Usman
Published: April 2020

In general, studies about tariqa have put more emphasis on aspects related to ritual teachings and spiritual experience of the Sufi leaders. Little has been studied so far about how teachings of a Sufi order are related to cosmological concepts. This paper aims to analyze the cosmological concepts that are taught in the teachings of the Naqshbandi Sufi order in the district of Pauh, the city of Padang, West Sumatera. Data for this research are gathered through interviews, observation and documentation. These data are then analyzed with content analysis method. The research find that the Naqshbandi order perceives the notion of sharia as one that is intimately related with divine revelation and the universe’s law of order, a holistic approach that regards deeds of a sālik (a Sufi traveler) as part of the cosmic order. The existing seven types of sharia law outline seven layers of heaven and earth. Thus, a mystic attainment of martabah hakikat (degree of reality) represents seven layers of heaven and earth, which are manifested through amaliah lathāif (inner ‘worship’ rituals) - all of which are attributed to internal parts of the human soul, such as brain, heart, spleen, liver, lungs and all internal parts of the human physical body. Within the Naqshbandi Sufi order, all sālik aredevised to be able to attain close relationship with God, and to become an imagery of human’s mystical potentials in their everyday lives’ activities.
Lo feo en general y lo feo en Hegel y Rosenkranz
Authors: Salmerón Miguel
Published: April 2020

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Lévinas frente a la modernidad
Authors: Gallardo Cervantes Antonio
Published: April 2020

RESUMENLos intentos de la antropología moderna que se empeñan en comprender el misterio del hombre a partir del yo solutario y orientado hacia el conocimiento del mundo acaban consiguientemente con la pérdida misma del hombre. El ser del hombre se manifiesta inaferrable e inexistente desde el momento en que se intenta captarlo en su forma pura, separada y aislada de la comunión con el otro. Emmanuel Lévinas hará una crítica radical a la orientación de esta antropología egológica.PALABRAS CLAVELÉVINAS-MODERNIDAD-ANTROPOLOGÍA-ALTERIDADABSTRACTThe intents of the modern anthropology that are impelled in understanding the mystery of the man from me solitary and oriented toward the knowledge of the world finish consequently with the same loss of the man. To be of the man is declared impossible to take and nonexistent since the moment in which tries to grasp it in their pure form, separated and remote of the communion with the other. Emmanuel Lévinas will do a critical radical to the orientation of this anthropology egocentric.KEYWORDSLÉVINAS-MODERNITY-ANTHOROPOLOGY-OTHERNESS
Boghossian y los argumentos regla-circulares para la justificación de la lógica
Authors: Vilanova Arias Javier
Published: April 2020

resumenEn este trabajo se evalúa críticamente el papel de la Teoría de las definiciones implícitas (y en concreto la teoría de boghossian) en la resolución de dos problemas en torno al conocimiento de la lógica: el problema de la explicación (explicar cómo obtenemos creencias sobre nuestras reglas de inferencia), y el problema de la justificación (justificar que nuestras creencias así obtenidas son conocimiento). Se fijan cinco resultados a alcanzar: aprioricidad, factualismo, normatividad, aplicabilidad y no circularidad viciosa. Se argumentará que, aunque dichos resultados se pueden alcanzar respecto al problema de la explciación, no se evita circularidad viciosa en el problema de la justificaciónPALABRAS CLAVELÓGICA, CONOCIMIENTO, DEFINICIÓN IMPLÍCITA, CIRCULARIDADABSTRACTThis paper examines the rol of implicit Definitions Theory (specially Boghossian's theory) in the solution of two related problems about the status of logical knowledge: the explanation problem (how do we obtain beliefs concerning our rules of inference) and the justification problem (how do we know our beliefs concerning rules of inferences are justified). Five goals are assigned to the Implicit Definition Theory: apriocism, factualism, normativity, aplicability and not vicious circularity. it will be argued that these five goals are reached for the explanation problem, but nt for the justification problem. KEYWORDSLOGIC, KNOWLEDGE, IMPLICIT DEFINITION, CIRCULAR ARGUMENTS
Filosofía del mérito
Authors: Puyol González Ángel
Published: April 2020

RESUMENEl mérito es un valor absolutamente presente en nuestra sociedad, hasta el punto de que a su alrededor gira un modelo social propio: la meritocracia. El mérito y la meritocracia suelen asociarse a las aspiraciones igualitaristas de quienes confían en que los individuos sean valorados, en el acceso a las posiciones sociales, por su capacidad y no por otros requisitos moralmente irrelevantes como el origen social, étnico, cultural, el sexo, el aspecto físico, las creencias religiosas o la ideología. Pero, paradójicamente, tanto el mérito como la meritocracia tienen un escaso compromiso con el valor de la igualdad.PALABRAS CLAVEMÉRITO, MERITOCRACIA, IGUALDAD, IGUALDAD DE OPORTUNIDADES.ABSTRACTMerit is a moral value very present in our society. Around it, we have a specific social model: meritocracy. Usually, we think that to a large extent merit and meritocracy are part of an egalitarian society, in which everybody is treated, in the access to social positions, by their capabilities and not by arbitrary elements like social or cultural background, etnics, sex, physical appearance, religious believes or ideology. But, paradoxically, merit and meritocracy have a very little compromise with the value of equality.KEY WORDSMERIT, MERITOCRACY, EQUALITY, EQUALITY OF OPPORTUNITY
El fenomenalismo analítico de A. J. Ayer
Authors: Bogónez Herrera Fernando
Published: April 2020

RESUMENLa segunda etapa del pensamiento filosófico de Ayer es conocida como «fenomenalismo analítico» y se caracteriza por su afirmación: lo que conoce el sujeto no son más datos sensoriales. Esto conlleva la necesidad de de crear lo que se conoce como el lenguaje de «los datos sensoriales», que debería ser previo al lenguaje ordinario y al que podría traducirse el primero mediante la provisión de una serie de reglas con este objeto. Los problemas y las críticas, conectados con la caracterización de que sea un «dato sensorial» surgieron muy pronto y tales problemas provocaron que el propio Ayer fuese obligado a redefinir su posición filosófica.PALABRAS CLAVE:DATO SENSORIAL, FENOMENALISMO ANALÍTICO, ENTIDAD CUASIFÍSICA, ENTIDAD LINGÜÍSTICAABSTRACTThe second phase of Ayer’s philosophical thought is known as «analytical phenomenalism» and is characterized by his assertion: what the subject knows is not but sense data. This involved the need of creating what is known as the language of «sense data», which should be prior to the ordinary language, and into which the last one could be translated, by means of providing a series of rules on this purpose. Problems and criticism, linked to the characterization of what a «sense datum» could be, arose very soon, and such problems and criticism forced Ayer to redefine his philosophical position.KEY WORDS.SENSE DATUM, ANALYTICAL PHENOMENALISM, QUASI-PHYSICAL ENTITY, LINGUISTIC ENTITY
De Stirner a Nicómaco. Pensamiento sobre el poder desde Max Stirner
Authors: Gutiérrez Aguilar Ricardo
Published: April 2020

RESUMENEl presente artículo trata de mostrar la evolución de una concepción del poder concreta que lleva de Hegel a Stirner a través del papel desempeñado por el individuo. De esta forma, el individualismo aparece entre dos líneas enfrentadas de la metafísica y la teoría de la acción.PALABRAS CLAVEHEGEL, STIRNER, ACCIÓN, POLÍTICAABSTRACTThis article tries to show the evolution of one specific conception of power that leads from Hegel to Stirner through the role played by the individual. Thus, individualism appears between two conflicting lines of metaphysics and action theory.KEYWORDSHEGEL, STIRNER, ACTION, POLITICS
Experiencia estética y crítica del arte: Los planteamientos de John Dewey
Authors: De la calle Román
Published: April 2020

RESUMENEl trabajo se propone analizar la relación que John Dewey establece entre la experiencia estética y la crítica de arte. Dewey entiende la crítica como estadio mediador entre la expreiencia estética y la propia finalidad ilustrativa de la crítica. Asimismo, esta mediación es analizada como experiencia crítica, desarrollada en el proceso reflexivo y comunicativo del juicio crítico.PALABRAS CLAVEDEWEY-ESTETICA-CRITICA DE ARTEABSTRACTThe paper focuses on the relation John Dewey establishes betwerrn the aesthetic experiencie and art critique. Dewey conceives critique as a mediating stage betweeen the aesthetic experience and the critique's own enlightening finality. This mediation moreover is but a critical experience, deployed within the reflexive and communicative process of judgement. KEYWORDSDEWEY-AESTHETICS-ART CRITIQUE
La fenomenología en el espejo de la psicolingüïstica: una perspectiva vygotskiana
Authors: Klyukanov Igor E
Published: April 2020

RESUMENLa premisa que subyace a este artículo es que ninguna investigación racional puede ser puramente fenomenológica o puramente psicológica. Esta tesis, que se refleja en el propio título del artículo, está fundada en la naturaleza continua de la conciencia. Por otra parte, el presente artículo está fundamentado en las perspectivas de L. S. Vygotsky sobre la consciencia. Una cuidadosa comparación de los estudios fenomenológicos con la investigación psicolingüïstica basada en las ideas de Vygotsky revela muchos paralelismo significativos. un buen número de conceptos fenomenológicos, tales como lso de "interiorización", "apropiazión" "preconsciente"," intencionalidad","significado vivido/hablado", "comprensión", etc...aparecen, como en un espejo en los trabajos psicolingüísticos bajo los mismos o diferentes nombres. De manera que, en cada caso sometido a discusión, hay un concepto fenomenológico y su "doble" psicolingüístico. PALABRAS CLAVEBYGOTSKY-FENOMENOLOGIA-PSICOLINGUISTICAABSTRACTThe underlying premise of this paper is taht no rational inquiry can be purely phenomenological or purely psychological. this thesis, wich is reflected in the title of the paper, is based on the continuous nature of consciousness. on the other hand, the present paper is grounded in L. S Vygotsky'2 persopectives on consciousness. A careful comparison of phenomeological studies with consciousness. A careful comparison of phenomenological studies with psycholinguistic research based on his ideas reveals many significant parallels. A lot of phenomenological concepts, such as "interiorization", "appropriation", "pre-conscious", "intentionaity", "lived/spoken meaning", "grasping", etc..appear, as if in a mirror, in psycholinguistic works, under different, or the same, names. So, in each case, under discussion there is a pheomenological concept and its psycholinguistic "double"KEYWORDSVYGOTSKY.PHENOMENOLOGY-PSICOLINGUISTICS
ДИФЕРЕНЦІАЦІЯ ФОРМ ФІНАНСОВОГО ЗАБЕЗПЕЧЕННЯ ДІЯЛЬНОСТІ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ В УКРАЇНІ
Authors: Tkachenko Nataliia
Published: April 2020

Досліджено державні та приватні джерела фінансування закладів вищої освіти. Проведено порівняльний аналіз, виявлено позитивні та негативні сторони кошторисного та нормативно-подушового фінансування закладів вищої освіти. Ідентифіковані та охарактеризовані проблеми диференціації форм фінансового забезпечення діяльності закладів вищої освіти в сучасних умовах. Визначено критерії оцінювання ефективності бюджетних витрат на вищу освіту. Запропоновано запровадження коригуючих коефіцієнтів нормативно-подушного фінансування закладів вищої освіти. Обґрунтовано необхідність стимулювання банківських установ щодо надання пільгового кредитування громадян на здобуття вищої освіти.
Pengaruh Leverage, Likuiditas dan Ukuran Perusahaan Sebagai Variabel Moderasi Terhadap Kualitas Laba.
Authors: Marpaung Elyzabet Indrawati
Published: April 2020

Tujuan dari peneltian ini adalah untuk menentukan pengaruh leverage, likuiditas, ukuran perusahaan terhadap kualitas laba dan ingin menguji ukuran perusahaan sebagai variabel moderasi pada pengaruh leverage dan likuiditas pada kualitas laba. Populasi adalah perusahaan pertambangan yang tercatat di Bursa Efek Indonesia periode 2014-2016. Sampel adalah perusahaan yang diambil dari populasi menggunakan simple random sampling. Metode analisis data yang digunakan adalah model regresi.  Hasil penelitian menunjukkan bahwa leverage dan likuiditas memiliki pengaruh negatif terhadap kualitas laba. Kualitas laba dapat memoderasi pengaruh leverage dan likuiditas terhadap kualitas laba. 

Kata Kunci : Kualitas Laba, Leverage, Likuiditas, Ukuran Perusahaan
Uma proposta de acompanhamento técnico-pedagógico em cursos de Educação Profissional e Tecnológica a Distância
Authors: De Sá Filho Paulo , De Carvalho Marco Antônio
Published: April 2020

Este artigo relata os resultados da implantação de um processo de acompanhamento dos alunos de cursos de Educação Profissional e Tecnológica a distância de uma instituição de ensino brasileira, possuindo como objetivo a retenção dos alunos, com isso diminuindo a evasão escolar, que é uma problemática existente em diversos sistemas educacionais no mundo. Nesse estudo, utilizamos como método o estudo de caso, por ser uma proposta desenvolvida com um grupo específico de indivíduos, no que tange a sua caracterização, trata-se de uma pesquisa quali-quantitativa, pois avalia questões subjetivas e ao mesmo tempo mensura dados diversos. E por último, revela que quando se propõe um acompanhamento técnico-pedagógico dos educandos em especial na Educação a distância os resultados são positivos, com isso, colabora para a redução dos altos índices de abandono escolar.
Factores determinantes de la reputación gubernamental: una ponderación a través del algoritmo de Saaty
Authors: Moreno Manzo Joanna Margarita , Navarro Chávez José César Lenin
Published: April 2020

Los bajos niveles de aprobación tanto de gobiernos como de gobernantes en el ámbito internacional implican un problema de legitimidad política. Parte del éxito de una organización depende de su reputación y de cómo es vista por sus stakeholders. En este contexto, se plantea encontrar los factores que determinan la reputación gubernamental para lo cual se instrumentó un método de ponderación de variables a través del algoritmo de Saaty con base en la revisión de la literatura de más de treinta obras. De los resultados obtenidos, se encontró que el desempeño gubernamental, el comportamiento ético, el liderazgo de las autoridades y la comunicación gubernamental son las variables que más incidieron en la reputación gubernamental.
Prvenstvo prava pred idejama dobra
Authors: Popović Petar
Published: April 2020

U radu se analizira pojam prava u
političkoj koncepciji pravednosti Johna Rawlsa. Nakon analize Rawlsovih
relevantnih tekstova koji sadrže određene sastavnice argumenta o pojmu prava
kao institucije, pravnog sustava, pravnih normi i pravâ osoba, kao i sekundarne
literature o tim tekstovima, istražuje se metajuridičko utemeljenje Rawlsove
koncepcije prava. Potom se argumentira kako je Rawlsov argument za prvenstvo
ispravnoga pred idejama dobra ključna teza za ispravno shvaćanje njegova
pravnoga konstruktivizma. Utvrđuje se kako se u njegovoj misli može s punim
pravom govoriti o, tzv. prvenstvu prava pred idejama dobra. Analizira se i
Rawlsovo shvaćanje prirodnoga prava. Zaključno se vrednuju rezultati članka s obzirom na pitanje o smještanju Rawlsovog pojma
prava u suvremene pravno-filozofske debate.
Pravne posljedice provjere putnikovih putnih isprava u zračnim lukama
Authors: Primorac Željka
Published: April 2020

Autorica se u radu bavi pravnoteorijskom elaboracijom suzbijanja
nezakonite migracije putnika u zračnom prijevozu (s naglaskom na državljane
trećih zemalja) ukazujući na modalitete i pravne posljedice provođenja provjere
valjanosti i vjerodostojnosti putnikovih putnih isprava prema najnovijim
rješenjima schengenske pravne stečevine te ocjenjujući ulogu zračnog
prijevoznika u zaštiti vanjske granice EU. Autorica ukazuje na nedovoljnu
pravnu reguliranost pojmova „neodgovarajuća putna dokumentacija“ i „potrebne
putne isprave“ preispitujući pravne učinke posjedovanja i predočenja neodgovarajuće putne
dokumentacije kao opravdanog razloga uskraćivanja ukrcaja putnika na let prema
rješenjima Uredbe (EU) 261/2004 i tumačenjima predmetne odredbe prema
rješenjima Smjernica iz 2016. U tom kontekstu, cilj je rada ukazati na aktualne
promjene u pogledu privatnopravne zaštite putnika prema važećim europskopravnim
rješenjima, ali i na najnoviji postupak pred Sudom EU-a (slučaj C-584/18) glede
tumačenja pojedinih rješenja europskopravnih propisa važećih za ovu problematiku (Uredbe (EU) 261/2004 i Uredbe (EU) 2016/399).
Završno se analiziraju obveze zračnog prijevoznika snositi financijske sankcije
(novčane kazne) u slučaju prijevoza putnika bez potrebne putne isprave te predlažu
rješenja de lege ferenda.
Arctic Diplomacy: A Theoretical Evaluation of Russian Foreign Policy in the High North
Authors: Nick Pay Vahid , Calvo Harry Gray
Published: April 2020

International interest in the Arctic is heating up along with the planet’s atmosphere and the region is increasingly presented as a new potential hotspot for inter-state competition and discord. Inevitably, Russia is often at the centre of this implicitly ‘realist’ narrative. This study provides an evaluation of Moscow’s Arctic policy between 2000 and 2019 from an international relation theory perspective by building upon the burgeoning literature on the Arctic and sources on Russian foreign policy in general. This study postulates that several elements of Russian regional policy in the High North do indeed follow realist readings of the international politics yet it also demonstrates how structural realism fails to adequately account for the institutionalization of regional relations and, most notably, neglects the importance of domestic factors, specifically historical memory, towards understanding Moscow’s contemporary Arctic policy.
Neurodegenerative diseases and cancer: sharing common mechanisms in complex interactions
Authors: Rojas Natalia González , Cesarini Martin , Etcheverry José Luis , Prat Gustavo Andrés Da , Arciuch Valeria Antico , Gatto Emilia Mabel
Published: April 2020

Several epidemiological studies support low cancer rates in patients with neurodegenerative disorders, including Parkinson's disease, Huntington’s disease, and Alzheimer's disease. Different mechanisms were raised as possible causes, from mutated tumor suppressor genes (PARKIN, PINK1) to small interfering RNA based on the CAG trinucleotide repeat expansions located in introns or untranslated regions. However, as every rule has an exception, some tumors have an increased incidence in these neurodegenerative diseases such as breast and skin cancer (melanoma). This mini-review aims to establish the epidemiology between these neurodegenerative disorders and cancer to determine the possible mechanisms involved and therefore set eventual therapeutic applications. According to our findings, we conclude the presence of an inverse relationship among most cancers and the aforementioned neurodegenerative disorders. However, this concept needs to be considered cautiously considering specific genetic and extra-genetic linkage factors for particular tumors.
Impact of lipoprotein(a) on long-term outcomes after percutaneous coronary intervention in patients with reduced low-density lipoprotein cholesterol
Authors: Liu Yuhong , Zeng Zhihuan , Yu Xing , Li Tudi , Yao Yusi , Chen Rong , Zheng Jianyi
Published: April 2020

The purpose of this study is to investigate the effect of lipoprotein(a) level on long-range prognosis after Percutaneous Coronary Intervention (PCI) in patients with low-density lipoprotein cholesterol (LDL-C) goal attainment. In this retrospective study, 350 patients in Coronary artery disease (CAD) with LDL-C less than 1.8 mmol/L were enrolled in the Guangdong Institute of Cardiovascular Diseases from January 2011 to December 2013. Follow-up was 1 year after PCI. According to the median value of the study population based on Lp(a), the patients were assigned to the high-level group and low-level group. The clinical data of the 2 groups were collected. We compared the baseline data between the 2 groups and the incidence rate of major cardiovascular events. After statistical analysis, the gender composition, hypertension, diabetes, and age of the patients between the 2 groups were similar, and the distinction was not significant. There was no significant distinction in cardio-vascular death, ischemic stroke, and recurrent myocardial infarction between the 2 groups, but the incidence of revascularization was higher in the high-level group (P < 0.05). High Lp(a) level predicts an increased incidence of revascularization of patients in CAD with LDL-C less than 1.8 mmol/L after PCI.
RESUME PENGERTIAN METODOLOGI ANALISIS
Authors: Febriana Dwi
Published: April 2020

Pada Era Teknologi sekarang,sistem sering digunakan untukmempermudah manusia untuk melakukan segala pekerjaan atau kegiatan baik dari berbelanja,belajarhingga bekerja. Pengembangan Sistem merupakan salah satu teknik dalam membuat penyususnan suatu sistem yang baru untu kmenggantikan sistem yang lama secara keseluruhan atau memeprbaiki sistem yang telah ada. Metodelogi Analisis adalah yang digukan untuk memperoleh kebenaran menggunakan penelusuran dengan cara tertentu dalam menemukan kebenaran,metodelogi tersusun daricara cara yang terstrukturuntuk memperoleh ilmuKataKunci : Pengertian Metodelogi Analisis
170. CSRID Journal, Vol.2 No.3 Oktober 2010, Hal. 170 - 179 AUDIT SISTEM INFORMASI UNTUK MEWUJUDKAN TATA KELOLA SISTEM INFORMASI (IT GOVERNANCE) DI ORGANISASI BERBASISKAN TEKNOLOGI INFORMASI
Authors: eryani Vivi
Published: April 2020

ABSTRAK Audit merupakan suatu proses terpadu mengenai pengumpulan, penilaian dan pengujian atas aktifitas suatu kegiatan. Audit Sistem Informasi merupakan proses terpadu kegiatan yaitu melakukan pengumpulan, penilaian dan pengujian atas aktifitas kegiatan di lingkungan Sistem Informasi.Dengan mengacu pada COBIT (Control Objective for Information and Related Technology) dapat digunakan sebagai alat yang dapat digunakan untuk mengefektifkan implementasi sistem informasi dalam perusahaan. COBIT terdiri dari 4 (empat) domain, yaitu Planning-Organization, Acquisition-Implementation, Delivery-Support dan Monitoring.COBIT framework digunakan untuk menyusun dan menerapkan model audit system informasi dengan tujuan untuk memberikan masukan dan rekomendasi bagi pihak manajemen perusahaan untuk perbaikan pengelolaan sistem informasi (IT Governance) di masa mendatang. Kata Kunci : Audit Sistem Informasi, Pengumpulan, Penilaian, Pengujian, IT Governance
Lembar Kerja Document Base Test Tasya Calvina Fauzan 1810111220031
Authors: Fauzan Tasya Calvina
Published: April 2020

Lembar Kerja Document Base Test Dikerjakan oleh : Tasya Calvina Fauzan
Digital Pathways, Pandemic Trajectories. Using Google Trends to Track Social Responses to COVID-19
Authors: Beytía Pablo , Infante Carlos Cruz
Published: April 2020

We already know which countries have controlled the spread of COVID-19 better and what “good practices” have enabled them to do so. Eventually, some of these policies could be replicated in other countries. But it is not enough to make a well-informed public intervention. We also need quickly available indicators of how actively populations are responding to the virus threat because current changes in social behaviour could mean significant differences in the spread of the COVID-19 in two weeks (after the incubation period). In this article, Pablo Beytía Reyes and Carlos Cruz Infante explore the potential of Google Trends to quickly track social responses to the pandemic. In all the countries that have reached a downward changepoint in the COVID-19 contagion, an “information saturation peak” preceded it: people were massively searching for information on the subject over 2 to 5 days, and about a week after the peak of searches was reached, a decline in the growth trend of coronavirus confirmed cases could be observed. Does it make sense to associate a Google search boom with a decrease in transmission trends? The authors propose that the frequency of searches is a quick indicator of 1) people’ concerns on the virus, 2) the development of a more informed citizenry on how to avoid transmission and 3) active social response to the virus spread, which generally lead to a downward change in the contagion trend.