bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of uterine artery doppler in prediction of pre-eclampsia
Authors: I. Patel Jigisha , Deliwala Kruti J. , Shah Sapana R. , Parikh Purvi M.
Published: May 2024

Background: Approximately 5-10 % of pregnancies are complicated by pre- eclampsia and it is a prime cause for maternal and perinatal mortality and morbidity worldwide, particularly in developing countries. In pre-eclampsia insufficient invasion of maternal spiral arteries by the trophoblast early in gestation due to abnormal implantation or maternal vascular disease results in impaired placental perfusion. Aspirin is a potent anti-inflammatory drug, has been shown to inhibit the biosynthesis and release of prostaglandins, even in low dosage. Ingestion of low dose aspirin may result in a decrease in the incidence of pre-eclampsia and fetal growth restriction and the precise mechanism by which it prevents preeclampsia in some women is also uncertain.
Methods: The present prospective observational study was carried out in females between 18-20 weeks of gestation with raised uterine artery PI attending antenatal clinic in obstetrics and gynaecology department in SVP Hospital Ahmedabad from May 2023 to December 2023 using Microsoft excel and SPSS version 23.
Results: In this study all the females were with raised uterine artery PI in 18-20 weeks ultrasound among them 51.85% were normotensive in later pregnancy. 48.14% developed pre-eclampsia in later pregnancy. In our study the middle cerebral artery indices in doppler ultrasound showed increased diastolic flow (including brain sparing effect) among 37% of the patients. The umbilical artery doppler showed that 62.9% of subjects were having normal umbilical artery indices, 18.5% of the patients were having decreased diastolic flow, 11.1% of the patients were having reversal of diastolic flow and 7.4% of the patients were having absent end diastolic flow
Conclusions: Doppler study for fetal surveillance in pre-eclampsia is a very useful and non-invasive method and abnormal uterine artery velocimetry lead to the worse pregnancy outcomes in the present study. The knowledge of uterine and umbilical artery doppler is very helpful to improve pregnancy management and to identify and assess hypertensive disorder of the pregnancy at early gestational age compared to other antepartum test modalities.
Adult granulosa tumor of the ovary about a case
Authors: Diakhate Abdoulaye , Niass Ami , Gning Gory , Ndiaye Mame Diarra , Moreira Philippe
Published: May 2024

Granulosa tumors are rare tumors of the ovary (0.6 to 3%). They belong to the group of mesenchymal and sex cord tumors, and represent more than 70% of malignant tumors in this group and 5% of ovarian cancers. They present two histological forms: the juvenile form and the adult form, the most common, occurring mainly in women in the post-menopausal period. The solido-cystic appearance of these tumors is generally non-specific and the histological diagnosis can be confirmed by immunohistochemistry. Surgery remains the basis of treatment and must be extensive in elderly patients. The prognosis depends on the histological type and several parameters. We report the observation of a 53-year-old patient without known risk factors, who presented with a granulosa tumor of the left ovary diagnosed postoperatively. The epidemiological, clinical and therapeutic aspects are discussed.
A massive degenerated uterine leiomyoma masquerading as an ovarian malignancy: a diagnostic dilemma
Authors: Negi Ayushi , Varun Neha , Tomar Swati , Sharma J. B.
Published: May 2024

Leiomyoma of the uterus is the most common tumour of the female pelvis arising from the uterine smooth muscle. Large cystic degenerations and leiomyomas located in the adnexa can mimic ovarian malignancy and challenge the radiologist and the operating surgeon. We report here an unusual case of large cystic, degenerated uterine leiomyoma mimicking malignant ovarian tumour on imaging.
Acute postpartum pleural effusion causing distress for patient and obstetrician
Authors: Poomalar G. K. , S. Padmapriya , . Bupathy , Praveen R.
Published: May 2024

A 31-year-old Gravida 5 Para 2 Live 2 Abortion 2, without comorbidities, underwent spontaneous vaginal delivery at term. She was asymptomatic in postpartum and had puerperal sterilization under low risk on postnatal day 4. After fourteen hours of surgery, she experienced an acute onset of breathlessness, tachypnea, and orthopnoea. Workup revealed right-sided pleural effusion filling three-fourths of the cavity with consolidation on chest X- ray. Therapeutic thoracocentesis was performed draining 600 ml of straw-coloured fluid. She was started on the Piperacillin tazobactam combination. Due to the repeated collection and persistent symptoms, a continuous intercostal drain was placed after 4 days. Due to persistent fever spikes, antibiotics were stepped up to Linezolid and Meropenem. A negative result on the Mantoux test, CBNAAT, and IGRA test was obtained. ANA profiling revealed the presence of non-specific KU antibodies. Symptomatic improvement was noted, and the ICD was subsequently removed after 6 days of insertion. Pregnancy is an immunosuppressive state. Rapid reversal of this state in postpartum results in a flare-up of quiescent infection. Even auto-immune diseases flare up in postpartum. Understanding this phenomenon of immune reconstitution syndrome and its impact will help in the management planning of postpartum women without dilemmas.
Comparative analysis of analgesic consumption and pain relief in patients receiving 0.25% bupivacaine versus those without intervention
Authors: Kamal Faysal , Siddique Ibrahim , Khan Arif Salam
Published: May 2024

Background: Laparoscopic cholecystectomy, now a standard for gall bladder surgery in symptomatic cholelithiasis, has significantly renovated our perspective on the postoperative recovery of patients undergoing cholecystectomy. However, pain stands out as a significant factor necessitating overnight stays after laparoscopic cholecystectomy. This study investigates the comparison of the analgesic and pain relief between groups who will receive 0.25% bupivacaine and group will not receive 0.25% bupivacaine.
Methods: A cross sectional study that was carried out in the department of surgery in Bangabandhu Sheikh Mujib Medical University, Dhaka over a period of six months and comprised 40 patients scheduled for laparoscopic cholecystectomy.
Results: At 12 hours after surgery, group I had a lower mean Numeric Rating Scale (NRS) score for pain (4.1±1.21) compared to group II (7.95±0.6). The difference between the groups was statistically significant (p<0.05). The mean NRS score for pain at 12 hours postoperatively was significantly lower in group I (4.72±0.61) compared to group II (6.08±0.64), suggesting a substantial reduction in pain intensity with the use of Bupivacaine during the initial 12 hours after surgery.
Conclusions: Considering the observed effectiveness of local administration of 0.25% bupivacaine at the port sites in reducing postoperative pain and the associated decrease in the need for conventional analgesics, patients undergoing laparoscopic cholecystectomy may benefit from discussing this pain management approach with their healthcare providers.
Importance of high-frequency and low-frequency three-dimensional endoanal ultrasound scan in diagnosing perianal fistula and abscess
Authors: Meegada Someswara Rao , Alapati Kishore V. , Varughese Mathai
Published: May 2024

Background: Three-dimensional endoanal ultrasound scanning (3D-EAUS) is the first line of investigation in the management of perianal fistula and abscess. High frequency (HF) and low frequency (LF) are 2 frequency modes in 3D-EAUS which have different resolutions and penetration depth. Our study aims to compare the 3D images of HF with LF modes.
Methods: This is a retrospective study of the 3D-EAUS images of patients with perianal fistula and abscess (perianal sepsis) who underwent 3D-EAUS from January 2019 to December 2020 in our hospital. The scans with both high and LF setting images were included in our study
Results: The 53 3D-EAUS images were randomly selected, out of them images with both HF and LF modes were included. The dimensions of both HF and LF 3D cuboid images were measured. The volume of tissue measured in HF and LF modes were 155 ml and 380 ml respectively. The LF images scored 22/24 points and the HF images scored 16/24 points.
Conclusions: LF and HF modes complement each other. LF mode can better delineate tracts and abscesses in extra-sphincteric space than HF mode. HF mode can better delineate tracts and abscesses in inter-sphincteric space as well as internal openings. We recommend routine use of both frequency modes while performing 3D-EAUS. Operating surgeons should gain expertise in performing the scan and reading the 3D image.
Primary spinal glioblastoma multiforme: a case report
Authors: Syed Aaqid Siraj , Sehgal Sanjana , Pandey Sanjeev K. , Tiwari Brijesh K. , Kumar Ranjit , Gupta Meenu
Published: May 2024

Spinal cord glioblastoma multiforme (GBM) is an uncommon disease within spinal tumours. According to our review of literature, less than 200 patients have been reported so far. Here we highlight the case of a 35 year female who complained of mild and intermittent lower back pain that radiates to bilateral thighs and was associated with tingling and numbness over both feet. The patient was evaluated and operated elsewhere with L1-L2 laminectomy and micro-surgical excision and it was reported as a case of myxopapillary ependymoma. However, immunohistochemical (IHC) stains were positive for GBM grade IV. A residual tumour was seen in postoperative magnetic resonance imaging (MRI) at our institute. Subsequently, the patient was subjected to adjuvant radiotherapy (RT) and regular Temozolomide chemotherapy following near-total resection of the mass. Aggressive management of this condition with timely chemo radiation is needed to enhance survival and assure a decent quality of life.
Landscape Inequalities and the Social Production of the Environment: on Setha Low's Book “Spatializing Culture”
Authors: Sharova Veronika
Published: May 2024

The article is a review of the book by social anthropologist and geographer Setha Low “The Spatial Embodiment of Culture. Ethnography of Space and Place” (originally, Spatializing Culture: The Ethnography of Space and Place), first published in Russian. Using the methods of social anthropology and ethnography, Setha Low explores how cultural and political transformations affecting the interests of individuals and groups are reflected in the space of modern cities. Lowe's book provides a detailed overview of two conceptual approaches – the social production of space and the social construction of space. The author also addresses the problem of the relationship between discourse, language and embodied space, which, among other things, has special emotional qualities that affect the everyday life of the city dweller. The article reveals a number of the main points of the book; it concludes that the issues raised in the book and the examples illustrating them go far beyond applied ethnographic research and are embedded in the broader context of contemporary political science, social theory and interdisciplinary research.
Navigating the intersection of sustainability and intelligent automation: Opportunities and challenges for entrepreneurs
Authors: MoÅŸteanu Narcisa Roxana
Published: May 2024

The business world is currently undergoing a significant shift towards sustainability and intelligent automation, which presents both promising prospects and formidable hurdles for business owners. The increasing demand for sustainable goods and services, driven by pressing social and environmental issues, opens doors for entrepreneurs to establish companies that address these concerns. Moreover, automation and technological advancements have revolutionized the operational landscape of firms, providing entrepreneurs with novel opportunities to enhance efficiency and foster creativity. However, thriving in this dynamic environment necessitates a fresh skill set and innovative approaches. Entrepreneurs must actively acquire the requisite technological expertise to leverage the potential of intelligent automation while navigating the intricate legislative and social frameworks surrounding sustainability. Furthermore, they must demonstrate agility and adaptability, adept at pivoting strategies and offerings to align with the evolving business panorama. This study’s exploration of the intersection of automation and entrepreneurship resonates deeply with the principles of sustainability. By dissecting the challenges and strategies entrepreneurs use to embrace automation, the research contributes valuable insights to the ongoing discourse on feasible business practices within the context of burgeoning sustainability. The findings will assist policymakers by providing useful information to cultivate an environment conducive to sustainable, technology-based entrepreneurship.
Comparison of Life Ways From the Viewpoints of Slovak and Spanish University Students
Authors: Chmelárová Zuzana , Pasiar Ladislav , Cano Varela Diana Patricia
Published: May 2024

Life ways are the events and experiences that shape an individual's personality, influenced by values, goals, and attitudes. The research question arising is whether preferred life ways of university students in Spain and Slovakia are different or not. Research areas were based on 13 styles and values in an individual's life in a very broad and complex context that captures the meaning and purpose of life and the values on which it stands. The main goal of the research is to determine whether the life paths of Slovak and Spanish students are different or similar. The research sample consists of 210 Slovak and 102 Spanish students. Data were collected by questionnaire describing all life ways in detail and for statistical analysis we used one-way, multifactorial analysis of variance (ANOVA). Slovak and Spanish students both prefer a lifestyle focused on experience and joy, considering it the most suitable for creating a favourable impression, while self-control with stoicism is inadequate to create it. However, Spanish students also value self-knowledge and independence, which are less emphasized by Slovak students, and they more frequently experience calm and receptive expectations as well as self-control with stoicism. Both groups note a discrepancy between their desired and actual lifestyles, particularly in striving for reason and moderation.
Canadian Society of Vertebrate Palaeontology Annual Meeting Abstracts 2024
Authors: Murray Alison M , Brink Kirstin B. , Holmes Robert B.
Published: May 2024

CSVP 2024 Abstract Volume
The reason of blurring regions of phase pattern for autodine signal of semiconductor laser during movement of the external reflector
Authors:   Saratov State University, Usanov Dmitrij , Skripal Anatolij ,   Saratov State University, Kalinkin Mikhail ,   Saratov State University
Published: May 2024

The computer simulation of the experimentally observed blurring of phase trajectories on the certain parts has been made with the help of numerical calculations of the system of differential equations for semiconductor laser with vibrating external reflector. The relation of the blurring of trajectories with generation of relaxation oscillations on these parts has been found. It has been shown that semiconductor laser in the generation regime of relaxation oscillations has the high sensitivity to the fluctuations of parameters of external optical feedbackand to the non-stability of power supply.
Parameters of limit cycle in recursive second-order digital system with one quantizer
Authors:   P. G. Demidov Yaroslavl State University, Brjuhanov Jurij , Myasnikov Evgenii ,   P. G. Demidov Yaroslavl State University
Published: May 2024

Parameters of limit cycles in second—order digital system with non—linear adder are investigated. Two kinds of quantization way are considered: rounding and value truncation. New analytical and computer aimed methods are proposed for investigation of limit cycles parameters dependencies upon the system coefficients. Upper bounds of limit cycles amplitudes are obtained by the first method. These bounds are rational functions of system coefficients and are verified by the second method.
Análisis de las variaciones del impuesto de renta en Colombia entre 2012 y 2022: un estudio de caso de ingresos laborales
Authors: Arango Saldarriaga Daniela , Toro Restrepo María Alejandra , Vásquez López Julián , Guerra Gómez Jackeline
Published: May 2024

El impuesto de renta se ha convertido en una de las principales fuentes de ingresos del Estado para financiar las políticas y los proyectos públicos. Es por ello que esta investigación profundiza en los efectos de las distintas reformas tributarias reali­zadas entre 2012 y 2022 en los ingresos laborales de las personas. Para el efecto, en primer lugar se relacionan los cambios en el impuesto de renta producto de las reformas fiscales y las políticas gubernamentales entre 2012 y 2022, específica­mente en relación con los ingresos laborales de las personas naturales asalariadas; en segundo lugar se presenta la simulación matemática de un caso específico en este segmento de contribuyentes, y, por último, se analizan los factores económicos y sociales que influyeron en dichas transformaciones tributarias. En esta inves­tigación se usó una metodología cualitativa con enfoque descriptivo, se revisó la literatura respectiva y se analizó su contenido apoyada en datos cuantitativos, lo que permitió tener una visión más completa del fenómeno y obtener resultados más precisos que permitan orientar rutas de investigación futuras. Este estudio proporciona una visión integral de la evolución del impuesto de renta por ingresos laborales y sus implicaciones para los trabajadores y el Estado, hallazgos que son importantes para la toma de decisiones políticas y la planificación financiera de los individuos en el país.
Hatay İlinin Bazı Nadir ve Endemik Bitki Türlerinin Korunması Üzerine Bir Çalışma
Authors: Kayıkçı Samim , Oğur Erdinç
Published: May 2024

Bu çalışmada Hatay ilinde yayılış gösteren, nesli tehlike altında olan, nadir ve endemik bitki türlerinin güncel durumlarının belirlenmesi ve bu bitkilerin koruma altına alınması amaçlanmıştır. 2020-2022 yılları arasında yürütülen arazi çalışmaları sonucunda 20 adet bitki taksonunun güncel durumu belirlenmiş, herbaryum örnekleri hazırlanmış ve tohum örnekleri toplanmıştır. Herbaryum ve tohum örnekleri Ege Tarımsal Araştırma Enstitüsü Müdürlüğüne teslim edilmiştir. Bu bitkilerden 10’u dar yayılışlı (lokal) endemik türlerdir (Acantholimon laxiflorum, Noccaea ali-atahanii, Centaurea arifolia, Centaurea doddsii, Centaurea foliosa, Centaurea ptosimopappa, Dorycnium amani, Salvia sericeotomentosa var. hatayica, Salvia sericeotomentosa var. sericeotomentosa ve Scorzonera pacis). Endemik türlerin 2’si CR, 4’ü EN, 1’i VU ve 3’ü DD tehlike kategorilerinde yer almaktadır. Diğer 10 takson ülkemizde sadece Hatay ili ve yakın çevresinde yayılışı olan nadir türlerdir (Gonocytisus pterocladus, Helichrysum sanguineum, Hypericum russeggeri, Origanum laevigatum, Petrorhagia syriaca, Salvia aramiensis, Salvia cassia, Salvia viscosa, Thymus eigii, Verbascum antiochium). Bu taksonlardan 8’i VU ve 2’si DD kategorisinde bulunmaktadır. Yapılan gözlemlerde, tarım arazisine dönüştürme, aşırı toplama, madencilik, aşırı otlatma, yol yapımı ve yapılaşmanın bitkiler üzerindeki insan kaynaklı olumsuz etkiler olduğu belirlenmiştir. Bu türlerden, 2018 yılında keşfedilen ve yerleşim yerlerine çok yakın bir yerde ve çok dar bir alanda yayılış gösteren Noccaea ali-atahanii türünün çok acil olarak koruma altına alınması gerekmektedir.
Lake Baikal amphipods and their genomes, great and small
Authors: Drozdova P. B. , Madyarova E. V. , Gurkov A. N. , Saranchina A. E. , Romanova E. V. , Petunina J. V. , Peretolchina T. E. , Sherbakov D. Y. , Timofeyev M. A.
Published: May 2024

Endemic amphipods (Crustacea: Amphipoda) of Lake Baikal represent an outstanding example of large species flocks occupying a wide range of ecological niches and originating from a handful of ancestor species. Their development took place at a restricted territory and is thus open for comprehensive research. Such examples provide unique opportunities for studying behavioral, anatomic, or physiological adaptations in multiple combinations of environmental conditions and thus attract considerable attention. The existing taxonomies of this group list over 350 species and subspecies, which, according to the molecular phylogenetic studies of marker genes, full transcriptomes and mitochondrial genomes, originated from at least two introductions into the lake. The studies of allozymes and marker genes have revealed a significant cryptic diversity in Baikal amphipods, as well as a large variance in genetic diversity within some morphological species. Crossing experiments conducted so far for two morphological species suggest that the differences in the mitochondrial marker (cytochrome c oxidase subunit I gene) can potentially be applied for making predictions about reproductive isolation. For about one­tenth of the Baikal amphipod species, nuclear genome sizes and chromosome numbers are known. While genome sizes vary within one order of magnitude, the karyotypes are relatively stable (2n = 52 for most species studied). Moreover, analysis of the diversity of repeated sequences in nuclear genomes showed significant between­species differences.  Studies of mitochondrial genomes revealed some unusual features, such as variation in length and gene order, as well as duplications of tRNA genes, some of which also underwent remolding (change in anticodon specificity due to point mutations). The next important steps should be (i) the assembly of whole genomes for different species of Baikal amphipods, which is at the moment hampered by complicated genome structures with high repeat content, and (ii) updating species taxonomy taking into account all the data.
Heavy metal sorption with lignin-containing sludge from the pulp and paper industry
Authors: Shatrova Anastasia S. , Bogdanov Andrey V. , Tyukalova Olga V.
Published: May 2024

Relevance. At present, the problem of soil pollution with heavy metals, which are accumulated in the body of animals and plants, causing various toxic effects, is especially acute. Despite the existence of various methods of reclamation of disturbed lands, as a rule, their application is inefficient or expensive, especially when it comes to abnormally high concentrations of heavy metals. Thus, an extremely urgent task is to find effective and inexpensive ways to recultivate lands contaminated with high concentrations of heavy metals. The article considers one of the promising areas for the reclamation of such lands using a mixture obtained from the accumulated waste of lignin-containing sediments from the pulp and paper industry of Baikal Pulp and Paper Mill as sorbents. Aim. To study and evaluate the effectiveness of using a mixture, which includes frozen lignin-containing sediments of Baikal Pulp and Paper Mill, as heavy metal sorbent. Methods. To assess the sorption efficiency of the obtained sorbent from the frozen sediments of sludge-lignin, the samples of anomalously contaminated soils were taken from the industrial site of the former battery plant "Vostsibelement", located in Svirsk, Irkutsk region. To determine the surface structure of the obtained sorbent for the presence of micro-, meso-, and macropores, its surface was surveyed using a JEOL two-beam system. IR spectroscopy was used to establish the types of bonds between the sorbent and the extracted metals. Results. The studies have shown that the resulting sorbent from the frozen lignin-containing sediments of Baikal Pulp and Paper Mill has a porous structure with a predominance of mesopores, sorbing heavy metal ions, while a large number of micropores contributes to the occurrence of chemical sorption. The obtained IR spectra indicate the possibility of chemical sorption of lead as a result of the reaction of substitution of a hydrogen atom in various hydroxyl groups of the sorbent of the group of aromatic or carboxyl structures. At the same time, the resulting sorbent in terms of its sorption properties is not inferior to commercial natural sorbents – bentonite clay and grassroots peat. The conducted studies allow us to make a positive conclusion about the possibility of using the developed mixture as a sorbent for the immobilization of heavy metals during the reclamation of lands that are contaminated with high levels of heavy metals, including lead.
Review of modern coal drying methods with the evaluation of their efficiency
Authors: Salomatov Vladimir V. , Karelin Vadim A.
Published: May 2024

Relevance. The need to analyze the current state of the subject of coal drying in order to identify the most effective methods in terms of time and energy costs, as well as environmental safety and improve the quality of fuel. As practice shows, drying is one of the most important stages in coal preparation for combustion, it helps to increase thermal efficiency, reduce emissions and environmental pollution, increase energy capacity and improve combustion stability. Among the main methods of drying coal, drying with evaporation: A) rotary drying; B) drying in a fluidized bed; C) immersion drying with hot oil; D) drying in a microwave oven, as well as drying without evaporation: A) hydrothermal dehydration; B) mechanical/thermal dehydration; C) solvent extraction, can be distinguished. At the same time, each of these methods is constantly evolving and it is required to evaluate the influence of the dynamics of these changes on the key characteristics of drying. Aim. Review and analysis of modern methods of coal drying, the most efficient in terms of time and energy costs. Object. Wet material – coal, subjected to various drying methods. Methods. Search for works on the stated topic, checking the indication of the main drying parameters: time, energy consumption, etc. Based on the data obtained, a comparison of various drying methods was carried out, and optimal methods were recommended. Results. The authors have considered the modern methods of drying coal and assessed their effectiveness. Rotary drying, hot oil immersion drying, mechanical/thermal dehydration and solvent extraction were found to be the most energy efficient methods for drying coal. The paper considers the features of each drying method.
Thawing of permafrost rocks when exploiting geothermal wells in Eastern Siberia
Authors: Polovnikov Viacheslav Yu. , Bulba Elena E. , Shelemehova Sofia D. , Lyubivy Egor V.
Published: May 2024

Relevance. Ensured by well-known theses about energy security and transition to alternative energy sources, reducing environmental emissions and energy saving in various industries through the use of geothermal energy. The study of the thermal regimes of deposits of geothermal energy sources located in zones of permafrost is of particular interest. The operation of geothermal wells in permafrost is associated not only with the danger of collapses in the wellhead zone, but also with the destruction of well structures with the withdrawal of their operation for long periods of time. Aim. Numerical analysis of heat transfer in the area where geothermal wells are located, taking into account the real characteristics of a typical geological section to predict the thawing of permafrost in Eastern Siberia. Object. Typical geothermal well design, the main elements of which (columns, conductor and directions) are made of cement. Methods. The simple iteration cycle was used in conjunction with the methods of two fractional steps according to the splitting scheme and the sweep method to solve the problem by the finite difference method. At nodal points belonging to several areas, the thermophysical characteristics were calculated as arithmetic averages. The adequacy of the results of the numerical analysis is confirmed by varying the grid parameters, the energy balance at the boundaries of the calculation area, and comparing the research results with literature data. Results. The authors have carried out the analysis of heat transfer during the operation of geothermal wells in Eastern Siberia, taking into account the actual characteristics of permafrost rocks that vary with depth. It was revealed that the radii of thawing of permafrost for the conditions of Eastern Siberia are 12–17 meters. The feasibility of taking into account the dependence of the thermophysical characteristics of rocks/soils in accordance with the parameters of the geological section during the design, construction and operation of objects using geothermal energy is shown.
Investigación interdisciplinar sobre la arquitectura vernácula de Puntarenas
Authors: García-Baltodano Kenia , Méndez-Álvarez Dawa
Published: May 2024

La arquitectura vernácula está arraigada en la cultura, surgida sin la intervención profesional y basada en técnicas tradicionales transmitidas informalmente. En Costa Rica, este patrimonio ha sido poco explorado, lo que amenaza su conservación. El proyecto “Caracterización de la arquitectura vernácula en madera de la ciudad de Puntarenas a partir de una perspectiva interdisciplinar” liderado por el Tecnológico de Costa Rica busca comprender y preservar este legado. Involucra a investigadores y estudiantes de Arquitectura y Urbanismo, Ingeniería Forestal y Biología, permitiendo un análisis integral. Se centra en el distrito central de Puntarenas, ciudad histórica marcada por su relación con el mar y el turismo. A través de revisión bibliográfica, análisis de fotografías y talleres participativos, se han identificado 172 edificaciones de madera. Estas fueron clasificadas y se seleccionaron 75 inmuebles para un inventario detallado. Se elaboraron planos arquitectónicos, identificando especies de madera predominantes (cedro y pochote) y se realizaron estudios patológicos para detectar daños biológicos. El proyecto busca documentar y valorar la arquitectura vernácula, generando conciencia sobre su importancia cultural y promoviendo su conservación a través de la investigación y la colaboración comunitaria.
Confluence of social perception and environmental habitability in public spaces of indigenous communities of the Manantlán Reserve, Jalisco, Mexico
Authors: Martín del Campo Saray Francisco José , Bojórquez Morales Gonzalo , R.W. Gerritsen Peter
Published: May 2024

The social perception and environmental habitability that occurs in the public spaces of indigenous communities of the Sierra de Manantlán, Jalisco, Mexico; they refer to a sense of balance regarding the emotional and physical conditions of its inhabitants. Its social, political, cultural and customs organization mark a unique identity in its communal life. The social perception as a factor of regulation of their way of working, contributes to an efficient and supportive performance towards their own, care and respect towards the ecosystem and an organized mass intervention. The objective of the work was to evaluate the conditions of social perception and environmental habitability of inhabitants in the public spaces of of Ayotitlán and Cuzalapa, Jalisco. The project refers to the mutual interaction between inhabitants of the analyzed communities, for this, interviews were carried out with key actors of the localities and information cards were applied to users on social perception and environmental habitability. Likewise, the measurement variables of the climatic conditions were carried out during the sampling stage of the cold period. Regarding the analysis of the research data, multiple linear regression was used for a Pearson association between the study variables, the meteorological and complementary variables of the applied sampling were examined. According to the results obtained, it is seen that climatic conditions affect the performance of productive activities in public spaces of the inhabitants of Ayotitlán and Cuzalapa, Jalisco, however; their social perception rooted in their beliefs and customs generates links of ecotourism and cultural dynamism, in this way; the study contributes with the municipality of both locations to obtain accurate information regarding this item and can be used for the benefit of society.
Predictors of Mortality among Hospitalized Patients with COVID-19 in Egypt-A Retrospective Observational Study
Authors: Mohamed Abdel-Salam Elgohary  , Mostafa Mahmoud Elnakib  , Mohamed G Seadawy  , Mohamed Emam Mohamed5  , Elaraby Dina , Amany Ahmad Ibrahim  , Osama Hasan Bekheet  , Ashraf Ibrahim Zaki  , Mahmoud Zeinhom Abdelfattah  , Hesham Mosaad Sheshtawy  , Marina Raouf Abdelmessih Saleeb  , Nouran Ameen Hamza  , Nashwa Naguib Omar  , Ahmed Mahmoud ElShafei  , Jacklin Samir kamal6
Published: May 2024

The prediction of mortality and risk stratification of severe coronavirus disease 2019 (Covid-19) offers a rational approach for clinical support, health resource allocation, and implementation of protective interventions to optimize the treatment. Clinicians need these predictors that permit them to elderly patients with Covid-19 rapidly during the pandemic. Investigate demographic features, clinical characteristics, laboratory parameters, and pharmacological treatment received by individuals who died due to Covid-19 that may be predictors of mortality. A retrospective observational study. A single-center cohort in Almaza Fever Egyptian Hospital through three years of the pandemic, 2020, 2021, and 2022. About 194 elderly patients with Covid-19 were attendees of the hospital and died through three years of the pandemic, 2020, 2021, and 2022. A total of 64 cases were in 2020, 94 cases in 2021, and 36 cases in 2022. Main outcome measures: Mortality after a short stay of 9 days evaluated by the area under the curve (AUC), determination of the clinical features, and laboratory measures that may be predictors related to mortality over the three years of the pandemic. Our research found a statistically significant variation between the three years (2020, 2021, and 2022) regarding co-morbidities including IHD, renal and stroke (p-value < 0.05), treatment including Iverzine, chloroquine, remedisvir, and SL (P-value < 0.001), and symptoms including pneumonia status, cytokine storm, dyspnea, cough, anosmia, loss of taste and GIT symptoms (p-value < 0.005). After analysis, there were some predictors, including male sex, age, and hospital stay, that were positively associated with the deterioration of some laboratory measures and biomarkers such as IL-6 with mortality after a short period of stay (9 days) over time. The presented study showed a reliable prediction of mortality over time, so, it plays a crucial role in early patients’ identification who are at high risk of death. Therefore, the deteriorated cases should be closely monitored.
Factors Associated to The Occurrence of Stunting at The Primary Health Center in Madiun City, Indonesia
Authors: Arinaa Manasika Farida  , Linda Dewanti  , Ahmad Suryawan
Published: May 2024

Stunting, a common nutritional problem characterized by a child’s shorter stature due to growth failure, affects 11.5% of toddlers at Demangan Primary Health Center in Madiun, Indonesia. This research aimed to analyze factors linked to toddler stunting, using an observational analytical cross-sectional design. All toddlers visiting Demangan Primary Health Center’s Integrated Health Post in Madiun were involved in the study sample. Maternal pre-pregnancy BMI, maternal upper arm circumference (LILA), maternal weight gain during pregnancy, inter-birth interval, low birth weight, per capita income, parental education, maternal knowledge on toddler’s nutrition and parenting patterns of feeding were factors collected through questionnaires, Maternal and Child Health books, and primary health center records. Univariate and bivariate analysis results were tested using the Chi-Square or Fisher Exact test. In this study, 156 samples were obtained, consisting of 18 stunted toddlers (11.5%) and 138 normal toddlers (88.5%). Stunting associated with maternal pre-pregnancy BMI showed p=0.020, maternal upper arm circumference p=0.008, maternal weight gain during pregnancy p≤0.001, low birth weight p=0.001, per capita income p=0.007, and maternal knowledge on toddler’s nutrition had p=0.011. In conclusion, pre-pregnancy conditions significantly influence stunting. So, enhancing interventions for maternal health during pre-pregnancy is crucial for maximizing impact.
Predicting positive surgical margins in patients treated with robot-assisted partial nephrectomy: results from a prospectively maintained dataset of a single tertiary referral center
Authors: Mari Andrea , Grosso Antonio Andrea , Coco Simone , Cadenar Anna , Bacchiani Mara , Lambertini Luca , Massaro Eleana , Cangemi Vincenzo , Cianchi Gemma , Sandulli Alessandro , Conte Francesco Lupo , Salamone Vincenzo , Mariottini Riccardo , Giudici Sofia , Maida Fabrizio Di , Olivera Laura , Oriti Rino , Scelzi Sabino , Vittori Gianni , Masieri Lorenzo , Minervini Andrea
Published: May 2024

Aim: To identify the incidence and evaluate predictors of positive surgical margins (PSMs) after robot-assisted partial nephrectomy (RAPN) in patients with clinical T1 renal cell carcinoma (RCC).

Methods: After securing ethics committee approval, we analyzed our institution’s prospectively maintained RCC database. Our cohort included 1611 patients who underwent RAPN between January 2017 and December 2022. Surgical specimens were evaluated using standard practices, and the International Society of Urological Pathology (ISUP) grading system was employed.

Results: The majority (69.5%) of the 1,611 patients were males. Median age and Body Mass Index were 62.6 years and 26.9 kg/m2, respectively. Overall, 18.6% and 21.1% of the patients had an Eastern Cooperative Oncology Group (ECOG) score ≥ 1 and American Society of Anesthesiologists physical status (ASA PS) score ≥ 3, respectively. Surgical indications were elective in 90.5% of cases. The preoperative aspects and dimensions used for an anatomical (PADUA) score median was 8.0 (interquartile range: 7.0-9.5). The predominant histotype was clear cell RCC, accounting for 70.4% of the cohort. PSMs were detected in 6.7% of the patients. Multivariable logistic regression showed surgical indications with an odds ratio (OR) of 6.06 (P < 0.001), surface, intermediate, base (SIB) score > 1 with an OR of 2.37 (P = 0.001), and PADUA score with an OR of 1.10 (P = 0.006) were significant predictors of PSMs.

Conclusion: Attaining negative margins remains the oncological cornerstone of partial nephrectomy. Our data underscore that tumor-specific (PADUA score) and surgical parameters (imperative indication, SIB score > 1, off-clamp approach) are the principal determinants for PSMs after RAPN.
Emotional Eating and Uncontrolled Eating as Risk Predictors for Disordered Eating Attitudes in Candidates for Bariatric Surgery Treated at a Public Hospital in the Amazon
Authors: Kikuchi Jeane Lorena Dias , Carvalhal Manuela Maria de Lima , Inete Millena Borges , Souza Yasmym Dannielle do Espírito Santo , Moraes Tainá Martins , Costa Rafaela Lorena Viana , Gabbay Rafaelle Dias , Paracampo Carla Cristina Paiva , Gomes Daniela Lopes
Published: May 2024

This study analyzes the eating behavior and factors associated with the presence of disordered eating attitudes in patients undergoing bariatric surgery. It is a cross-sectional, descriptive, and analytical study conducted at a hospital in the Amazon region of Brazil. The Disordered Eating Attitude Scale reduced version (DEAS-s) was used to assess the risk of eating disorders and the Three-Factor Eating Questionnaire (TFEQ-R21) to characterize eating behavior. A total of 205 patients participated, with a mean age of 37.5 ± 8.6 years, the majority being female (93.7%; p<0.001), the mean BMI was 45.3±6.7 kg/m2. It was found that cognitive restraint had the highest mean (52.6±19.9; p<0.001). As for the DEAS-s, the question with the highest mean was "spending one or more days without eating or consuming only liquids to lose weight" (2.80±1.99). Female participants had a higher score in the emotional eating (p=0.016). Disordered eating attitudes showed a correlation with emotional eating and uncontrolled eating. These results suggest that candidates for bariatric surgery may have susceptibility to eating disorders. The importance of a multidisciplinary team in monitoring during the preoperative period is highlighted.
Comparison of the Proteome of Staphylococcus aureus Planktonic Culture and 3-Day Biofilm Reveals Potential Role of Key Proteins in Biofilm
Authors: Rahman Md Arifur , Amirkhani Ardeshir , Chowdhury Durdana , Vickery Karen , Hu Honghua
Published: May 2024

Staphylococcus aureus and coagulase-negative staphylococci account for about 80% of infections associated with medical devices and are associated with increased virulence due to their ability to form biofilm. In this study, we aimed to construct a comprehensive reference map followed by significant pathway analysis in the proteome of S. aureus biofilm grown for 3-days as compared with 24 h planktonic using a high-resolution TMT based MS. We identified proteins associated with secondary metabolites, ABC transporters, biosynthesis of amino acids, response to stress, and amino sugar and nucleotide sugar metabolism were significantly upregulated in the 3-day biofilm. In contrast, proteins associated with virulence factors, microbial metabolism in diverse environments, translation, and energy metabolism were significantly downregulated. GO functional annotation indicated that more proteins are involved in metabolic processes, catalytic activity, and binding in biofilm, respectively. Among the significantly dysregulated proteins, hyaluronidase (hysA) in conjunction with chitinase may play a significant role in the elimination and/or prevention of biofilm development. This study advances the current S. aureus subproteomes, identified potential pathways significant to biofilm biology and helped to understand their potential role in S. aureus which may shed light on developing new therapeutic regimes including antibiofilm agents in the treatment of biofilm-infections related with implantable medical devices.
Predicting Abiotic Soil Characteristics Using Sentinel-2 at Nature-Management-Relevant Spatial Scales and Extent
Authors: Moeslund Jesper Erenskjold , Damgaard Christian Frølund
Published: May 2024

Knowledge of local plant community characteristics is imperative for practical nature planning and management, and for understanding plant diversity and distribution drivers. Today, retrieving such data is only possible by fieldwork and is hence costly both in time and money. Here we used 9 bands from multispectral high-to-medium resolution (10–60 m) satellite data (Sentinel-2) and machine learning to predict the local vegetation plot characteristics at broad extent (approx. 30.000 km2) in terms of plants’ preferences for soil moisture, soil fertility, and pH, mirroring the levels of the corresponding actual soil factors. These factors are believed to be among the most important for local plant community composition. Our results showed that there are clear links between the Sentinel-2 data and plants abiotic soil preferences and using solely satellite data we achieved predictive powers between 26–59% improving to about 70% when habitat information was included as a predictor. This show that plants abiotic soil preferences can be detected quite well from space, but also that retrieving soil characteristics using satellites is complicated and that perfect detection of soil conditions using remote sensing – if at all possible – needs further methodological and data development.
Micropropagation and Synthetic Seeds Production of Humulus lupulus L. var. Mapuche: Optimization, Advances, and Agricultural Applications
Authors: Di Sario Luciana , Zubillaga María Fany , Zepeda Moreno Claudio Fernando , Pizzio Gastón Alfredo , Boeri Patricia Alejandra
Published: May 2024

Traditional asexual propagation of hops limits its phytosanitary quality and the concomitant plant availability. This scenario worsens with the global climate change. In this study we develop protocols for in vitro propagation of Humulus lupulus var. mapuche. Two explant types were evaluated: shoot tips, from field material collected in Río Negro province (Argentina), and nodal segments, from vitroplants. Different growth regulator, such as 6-Benzylaminopurine, gibberellic acid, indole-3-butyric acid and indole-3-acetic acid, was used to induce desired morphogenic responses. Additionally, the impact of abscisic acid application on acclimatization was assessed, and resulted in robust growth and reduced plant stress symptoms during ex vitro adaptation. Also, the study develops a protocol for synthetic seeds production, with storage at 4°C to enhance conservation and plant material transport, ensuring a constant supply of female plants. This comprehensive approach addresses current producer demands and emerging climate challenges. The findings highlight the fundamental role of in vitro multiplication of hops in improving plant material availability and quality, with significant implications for the brewing industry and related sectors.
Exploring the Phytochemical Composition and the Bioactive Properties of Malbec and Torrontés Wine Pomace from the Calchaquíes Valleys (Argentina) for their Sustainable Exploitation
Authors: Tapia Pablo Ezequiel , Silva Ana Margarida , Delerue-Matos Cristina , Moreira Manuela , Rodrigues Francisca , Torres Carro Romina , Santi María Daniela , Ortega María Gabriela , Blázquez María Amparo , Arena Mario Eduardo , Alberto María Rosa
Published: May 2024

Hydroalcoholic extracts from Malbec and Torrontés wine pomace (Vitis vinifera L.) originating from the high-altitude vineyards of Argentina's Calchaquí Valleys were characterized. Total phenolics, hydroxycinnamic acids, orthodiphenols, anthocyanins, non-flavonoid phenolics, total flavonoids, flavones/flavonols, flavanones/dihydroflavonols, and tannins were quanti-fied through spectrophotometric methods, with Malbec extract exhibiting higher concentra-tions in most of phytochemical groups when compared to Torrontés. HPLC-DAD identified more than 30 phenolic compounds in both extracts. Malbec displayed superior antiradical ac-tivity (ABTS cation, nitric oxide, and superoxide anion radicals), reduction power (iron, copper and phosphomolybdenum), hypochlorite scavenging, and iron chelating ability, compara-tively to Torrontés. The cytotoxicity assessments revealed that Torrontés affected the viability of HT29-MTX and Caco-2 colon cancer cells by 70% and 50%, respectively, at the highest tested concentration (1 mg/mL). At the same time, both extracts did not demonstrate acute toxicity in Artemia salina or in red blood cell assays at 500 µg/mL. Both extracts inhibited the lipoxygen-ase enzyme, with Malbec also reducing the tyrosinase activity and neither inhibited the xan-thine oxidase. The substantial phenolic content and diverse biological activities in Calchaquí Valleys' pomaces underline their potentialities to be valorized for pharmaceutical, cosmetic, and food industries.