bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital and analogue Phenomenology
Authors: Lanfredini Roberta
Published: October 2022

Phenomenology presents itself not as an explanation or interpretation of phenomena but as a description of them. Describing experience means making its internal structure explicit, which, in phenomenology, is an eidetic structure.

The method of phenomenological explication or clarification is, however, by no means univocal. This paper aims to isolate the two fundamental ways in which phenomenological description is achieved. The first refers to a phenomenology of manifestation, based on the concept of determination or datum, which is realized in the phenomenological-static approach and, in particular, on the concept of extensive quality. The second refers to a phenomenology of disposition, based on the concept of tension or force – which is realized in the genetic approach as well as in Merleau-Ponty’s phenomenology of perception – and, in particular on the concept of intensive or forceful quality.

The analysis of the difference between the two approaches allows us to introduce the crucial distinction between digital and analogue dimensions within phenomenology.
Linking Viscosity to Equations of State Using Residual Entropy Scaling Theory
Authors: Yang Xiaoxian , Xiao Xiong , Thol Monika , Richter Markus , Bell Ian H.
Published: October 2022

In our previous work (J Chem Eng Data 2021, 66(3):1385–1398), a residual entropy scaling (RES) approach was developed to link viscosity to residual entropy [a thermodynamic property calculated with an equation of state (EoS)] using a simple polynomial equation for refrigerants. Here, we present an extension of this approach to a much wider range of fluids: all pure fluids and their mixtures whose reference EoS and experimental viscosity data are available. A total of 84 877 experimental points for 124 pure fluids and 351 mixtures are collected from 1846 references. The investigated pure fluids contain a wide variety of fluids from light gases with quantum effects at low temperatures to dense fluids and fluids with strong intermolecular association. More than 68.2 % (corresponding to the standard deviation) of the evaluated experimental data agree with the RES model within 3.2 % and 8.0 % for pure fluids and mixtures, respectively. Compared to the recommended models implemented in the REFPROP 10.0 software (the state-of-the-art for thermophysical property calculation), if the dilute gas viscosity is calculated in the same way, our RES approach yields similar statistical agreement with the experimental data while having a much simpler formulation and fewer parameters. To use our RES model, a software package written in Python is provided in the supporting information.

Graphical Abstract
Canaloplasty and trabeculotomy with the OMNI® surgical system in OAG with prior trabecular microbypass stenting
Authors: Terveen Daniel C. , Sarkisian Steven R. , Vold Steven D. , Selvadurai Deepan , Williamson Blake K. , Ristvedt Deborah G. , Bleeker Adam R. , Dhamdhere Kavita , Dickerson Jaime E.
Published: October 2022

Purpose

Evaluate effectiveness and safety outcomes for patients treated with canaloplasty and trabeculotomy previously treated with a trabecular microbypass stent (TBS).

Methods

Retrospective, multicenter, IRB approved study. Patients treated with TBS (iStent/iStent inject, Glaukos) and subsequently with OMNI surgical system (OSS) (Sight Sciences). From 5 practices in 5 US states. Open-angle glaucoma (OAG), minimum 3 months follow-up after OSS surgery, Pre-OSS IOP ≥ 17 mmHg on ≥ 1 medication. No glaucoma procedures between TBS and OSS. Endpoints: proportion with ≥ 20% reduction in IOP, IOP between 6 and 18 mmHg, mean IOP, change in IOP, mean number of medications. Adverse events and secondary surgical interventions (SSI). Mann–Whitney rank sum test compared pre-OSS IOP and medications with follow-up.

Results

Twenty seven patients. Average age (SD) 72.2 (10.8), 22/27 primary OAG (82%), mean MD − 6.2 (7.0) dB. Mean IOP before OSS 22.3 (4.3) mmHg on 2.2 (1.3) medications. At last follow-up (mean 11 months) IOP was 17.2 mmHg on 1.8 medications, − 5.1 mmHg (− 23%, p < .001), − 0.4 meds (− 18%, p = .193); ≥ 20% IOP reduction (41%), IOP ≤ 18 (56%). Adverse events were non-serious. Hyphema > 1 mm (3, 11%), BCVA decrease (4, 15%), IOP spike (2, 7%). SSI (4, 15%) had higher pre-OSS IOP (23.4 mmHg) and worse MD (− 9.6 dB).

Conclusion

Patients uncontrolled by medication and a prior TBS would once have been candidates for trabeculectomy and tube shunts. OSS offered a minimally invasive option that provided IOP control and avoidance of traditional surgery for the majority over follow-up averaging 11 months and up to 42 months.
Transportation Sustainability and Relevant Ranking of European Countries
Authors: Grigoroudis Evangelos , Kouikoglou Vassilis S. , Phillis Yannis A.
Published: October 2022

The role of transportation in the economic process is central. Transportation’s benefits, however, can be dampened because of its environmental and social cost. A central question then arises as to the degre of sustainability of a national transportation system. In the present paper we develop a mathematical model to define and assess national transportation sustainability. The model relies on a number of indicators encompassing environmental impact, efficiency, safety, and economic contributions. Statistical data manipulations and fuzzy multistage reasoning result in an overall sustainability index over [0, 1]. A sensitivity analysis uncovers those indicators with the highest potential for improving transportation sustainability. Thirty European countries are ranked and the most important indicators for each country are pinpointed. It is demonstrated that greatest improvement will be achieved with the reduction of passenger car use, road freight transportation, and fatal accidents. Counterintuitively, Norway, Austria, Denmark, and Luxembourg rank at the bottom of the list together with Bulgaria, Greece, and Malta. This is due to their poor environmental performance and their small sustainability progress over 2010–2020.
Isolation and characterization of a main porin from the outer membrane of Salinibacter ruber
Authors: Farci Domenica , Cocco Emma , Tanas Marta , Kirkpatrick Joanna , Maxia Andrea , Tamburini Elena , Schröder Wolfgang P. , Piano Dario
Published: October 2022

Salinibacter ruber is an extremophilic bacterium able to grow in high-salts environments, such as saltern crystallizer ponds. This halophilic bacterium is red-pigmented due to the production of several carotenoids and their derivatives. Two of these pigment molecules, salinixanthin and retinal, are reported to be essential cofactors of the xanthorhodopsin, a light-driven proton pump unique to this bacterium. Here, we isolate and characterize an outer membrane porin-like protein that retains salinixanthin. The characterization by mass spectrometry identified an unknown protein whose structure, predicted by AlphaFold, consists of a 8 strands beta-barrel transmembrane organization typical of porins. The protein is found to be part of a functional network clearly involved in the outer membrane trafficking. Cryo-EM micrographs showed the shape and dimensions of a particle comparable with the ones of the predicted structure. Functional implications, with respect to the high representativity of this protein in the outer membrane fraction, are discussed considering its possible role in primary functions such as the nutrients uptake and the homeostatic balance. Finally, also a possible involvement in balancing the charge perturbation associated with the xanthorhodopsin and ATP synthase activities is considered.
Sea Lamprey Alarm Cue Comprises Water- and Chloroform- Soluble Components
Authors: Mensch Emily L. , Dissanayake Amila A. , Nair Muraleedharan G. , Wagner C. Michael
Published: October 2022

A diversity of aquatic organisms manage predation risk by avoiding waters activated with conspecific alarm cues, a chemical mixture released from injuries. The sea lamprey (Petromyzon marinus) is a nocturnal migratory species that relies on its alarm cue to navigate around areas of predation risk when moving through river channels. Identification of the cue’s chemistry would allow managers to harness this innate behavioral response to guide migrating sea lamprey to traps (invasive population in the Laurentian Great Lakes) or to fish passage devices where dams block migrations in their native range. We pursued isolation of the sea lamprey alarm cue through behaviorally guided fractionation, fractionating the alarm cue into water-soluble and chloroform-soluble fractions, each of which elicited a substantial avoidance response. Recombining the two fractions restored full reactivity, suggesting the alarm cue mixture contains components that exhibit high solubility in water (e.g., nitrogenous compounds), chloroform (e.g., lipids), or perhaps materials that dissolve readily in either solvent. We further screened 13 individual compounds or pure isolates and 6 sub-fractions from the water-soluble fraction and found one of the pure isolates, isoleucine, evoked an avoidance response on its own, but not consistently when found in other mixtures. In a third experiment, we observed no behavioral response after recombining 32 compounds isolated and identified from the water-soluble fraction. These results confirm other suggestions that the process of elucidating alarm cue constituents is challenging. However, we suggest the pursuit is worthwhile given the strong evidence for the utility of alarm cues for use in the conservation and management of fishes and other aquatic organisms.
The impact of habitat fragmentation on domatia-dwelling mites and a mite-plant-fungus tritrophic interaction
Authors: Graham Carolyn D. K. , Warneke Christopher R. , Weber Marjorie , Brudvig Lars A.
Published: October 2022

Context

Habitat fragmentation is a leading threat to biodiversity, yet the impacts of fragmentation on most taxa, let alone interactions among those taxa, remain largely unknown.

Objectives

We studied how three consequences of fragmentation—reduced patch connectivity, altered patch shape, and edge proximity—impact plant-dwelling mite communities and mite-plant-fungus interactions within a large-scale habitat fragmentation experiment.

Methods

We sampled mite communities from the leaves of Quercus nigra (a plant species that has foliar domatia which harbor fungivorous and predacious mites) near and far from edge within fragments of varying edge-to-area ratio (shape) and connectivity via corridors. We also performed a mite-exclusion experiment across these fragmentation treatments to test the effects of mite presence and fungal hyphal abundance on leaf surfaces.

Results

Habitat edges influenced the abundance and richness of leaf-dwelling mites; plants closer to the edge had higher mite abundance and species richness. Likewise, hyphal counts were higher on leaves near patch edges. Despite both mite and fungal abundance being higher at patch edges, leaf hyphal counts were not impacted by mite abundance on those leaves. Neither patch shape nor connectivity influenced mite abundance, mite species richness, or the influence of mites on leaf surface fungal abundance.

Conclusion

Our results suggest that mites and foliar fungi may be independently affected by edge-structured environmental gradients, like temperature, rather than trophic effects. We demonstrate that large-scale habitat fragmentation and particularly edge effects can have impacts on multiple levels of microscopic communities, even in the absence of cascading trophic effects.
Daily Stress Processes as Potential Intervention Targets to Reduce Gender Differences and Improve Mental Health Outcomes in Mid- and Later Life
Authors: Stawski Robert S. , Cichy Kelly E. , Witzel Dakota D. , Schuyler Ashley C. , Nichols Madeline J.
Published: October 2022

The current study examines daily stress processes as risk factors for comprised mental health in midlife and later life, specifically for gender differences in depression risk. Using data from the Midlife in the United States (MIDUS) study and the National Study of Daily Experiences (NSDE), we examine (1) gender differences in depression; (2) the prospective effects of differential exposure and affective responses on 10-year depression status; (3) gender differences in daily stress-depression links. Furthermore, we explore whether the protective factor of help-seeking behavior moderates the effects of daily stress on depression. Participants included 1289 (mage = 55; SD = 12; range = 34–83; 56% female) individuals who completed the second waves of MIDUS and the 8-day NSDE daily diary protocol and participated in the third wave of MIDUS approximately 10 years later. Respondents completed assessments of depression and their seeking assistance from a psychiatrist, mental health professional, counselor, or religious leader. Covariate-adjusted logistic regression analyses revealed increased odds of depression among women compared to men, but no significant gender difference after taking daily stress into account. Higher levels of stressor exposure, negative affect, and affective reactivity were associated with increased odds of depression for both men and women. Compared to those who did not engage in help-seeking behavior, those who did had significantly greater odds of depression, and there were asymmetric patterns of daily stress effects across groups. These findings highlight differential exposure, negative affect, and affective responses to daily stress as potentially accessible intervention targets for reducing stress in daily life and mitigating longer-term depression risk during mid- and later life.
Iodine status and supplementation in pregnancy: an overview of the evidence provided by meta-analyses
Authors: Croce Laura , Chiovato Luca , Tonacchera Massimo , Petrosino Elena , Tanda Maria Laura , Moleti Mariacarla , Magri Flavia , Olivieri Antonella , Pearce Elizabeth N. , Rotondi Mario
Published: October 2022

Iodine supplementation during pregnancy in areas with mild-moderate deficiency is still a matter of debate. The present study aimed at systematically reviewing currently available evidences provided by meta-analyses with the aim to further clarify controversial aspects regarding the need of iodine supplementation in pregnancy as well as to provide guidance on clinical decision-making, even in areas with mild-moderate deficiency. Medline, Embase and Cochrane search from 1969 to 2022 were performed. For the purpose of this review, only studies containing meta-analytic data were selected. A total of 7 meta-analyses were retrieved. Four meta-analyses evaluated the relationship between iodine status during pregnancy and neonatal and maternal outcomes suggesting the existence of a U-shaped correlation between iodine status and several maternal and neonatal consequences, especially if iodine status is evaluated at the beginning of pregnancy. Three meta-analyses evaluating the results of intervention trials failed to provide straightforward conclusions on the benefits of iodine supplementation in pregnant women in areas with mild-moderate iodine deficiency. Although evidence coming from meta-analyses suggests a role of iodine status during pregnancy in determining maternal and child outcomes, results of meta-analyses of intervention trials are still controversial. Several factors including, degree of iodine deficiency, and pooling studies conducted in areas with different iodine intake, may account for the lack of benefits reported by meta-analyses of intervention trials. More high-quality, randomized, controlled trials including information on timing, dose and regimen of iodine supplementation are needed to further elucidate this issue.
Students’ Representations of Menopause and Perimenopause: Out of Control Bodies and Empathetic Expert Doctors
Authors: Hayfield Nikki , Campbell Christine
Published: October 2022

Representations of peri/menopause are influential in relation to how peri/menopause is understood and how peri/menopausal women are perceived, both of which have important implications for health and wellbeing. In this paper, we report results from a story completion study with 102 undergraduate psychology students. Participants were invited to write a response to a fictional scenario about a peri/menopausal woman. Thematic analysis was used to construct two themes. In the first theme,Women’s bodies out of control, we report how students represented peri/menopausal women’s bodies as unpredictable and uncontrollable. In the second theme,Doctors as empathetic experts: A (biomedical) problem in need of (medical) intervention, we demonstrate how participants wrote stories that portrayed peri/menopause as a medical problem to be easily and effectively resolved by a doctor. These doctors were consistently characterized as empathetic and as experts of peri/menopause. We consider the extent to which these fictional stories might (or might not) map onto women’s lived experiences of peri/menopause by drawing on extant literature. Our results contribute to understandings of how young people represent peri/menopause and peri/menopausal women. These results have implications for educators in ensuring that menopause is included in their curricula, and for health professionals in their practice.
Simplified Kinetic Model for $$\hbox {NH}_3$$-SCR Over Cu-CHA Based on First-Principles Calculations
Authors: Feng Yingxin , Creaser Derek , Grönbeck Henrik
Published: October 2022

Selective catalytic reduction with ammonia as reducing agent ($$\hbox {NH}_3$$

NH
3

-SCR) is an efficient technology to control $$\hbox {NO}_\mathrm{x}$$

NO
x

emission during oxygen excess. Catalysts based on Cu-chabazite (Cu-CHA) have shown good performance for $$\hbox {NH}_3$$

NH
3

-SCR with high activity and selectivity at low temperature and good hydrothermal stability. Here, we explore a first-principles based kinetic model to analyze in detail which reaction steps that control the selectivity for $$\hbox {N}_2$$

N
2

and the light-off temperature. Moreover, a simplified kinetic model is developed by fitting lumped kinetic parameters to the full model. The simplified model describes the reaction with high accuracy using only five reaction steps. The present work provides insight into the governing reaction mechanism and stimulates design of knowledge-based Cu-CHA catalysts for $$\hbox {NH}_3$$

NH
3

-SCR.
Categorization of green and grey infrastructure complexity in the rural–urban interface of Bengaluru, India: an unsupervised volumetric approach with relevance for urban quality
Authors: Nölke Nils , Fehrmann Lutz , Plieninger Tobias , Kleinn Christoph
Published: October 2022

Trees are key elements of urban green infrastructure and provide multiple ecosystem services that are essential for the quality of life of people in urban environments. Grey infrastructure is made up of buildings or built-up area, generally characterized by imperviousness of the surface. The complexity of urban green and grey infrastructure and their interactions co-define the quality of urban life and the ecological value of urban areas. Using conventional dichotomies by separation into “urban” and “rural” contexts does hardly allow to comprehensively assess the situation in rapidly urbanizing environments of the Global South. We present an unsupervised remote sensing-based approach that integrates 3D information to objectively categorize the complexity of green and grey infrastructure. Using the rural–urban interface of Bengaluru, India, as a case example, we distinguished five categories that describe the composition and configuration of green and grey infrastructure, where three variables served as indicators for categorization into five clusters. We argue that such integrated 3D assessment of green and grey infrastructure is particularly useful for understanding and classifying “rurban” environments, where a distinction between urban and rural is often no longer possible. Our final map allows to quantitatively characterize such rurban configurations.
Seasonal Variability of Large-Sized Particulate Matter Concentrations
Authors: Dimou Vasiliki , Binopoulou Eleftheria , Malesios Chrisovalantis
Published: October 2022

Human exposure to particulate matter (PM) is of great scientific interest due to its impact on both human health and the environment (climate change, reduced visibility, deterioration of archaeological sites, etc.). The aim of the current paper was to study the concentration of large-sized particulate matter (PM10) in relation to the season of the year. Measurements were performed with the help of a personal Button Sampler in three repeated cycles, namely summer, autumn, and winter, in order to obtain comparable results from three different seasons of the year. A total of 45 samples were collected, 27 of which were obtained from a peri-urban Pinus brutia forest and 18 from an adjacent urban area (9 and 6 samples in each repeated sampling cycle, respectively). Results obtained from both sampling areas show a significant increase in PM10 levels during the summer (8.86 mg m−3/24 h) in comparison with the autumn and winter concentrations (3.71 mg m−3/24 h and 4.12 mg m−3/24 h, respectively).
Therapeutic Effects of Lipid Lowering Medications on Myocardial Blood Flow, Inflammation, and Sympathetic Nerve Activity Using Nuclear Techniques
Authors: Higuchi Takahiro , Serfling Sebastian E. , Rowe Steven P. , Werner Rudolf A.
Published: October 2022

Purpose of Review

Statins are routinely applied in patients with coronary artery disease, as they allow significantly to reduce blood cholesterol levels. Although those drugs are endorsed by current guidelines and prescribed routinely, a substantial portion of patients are still statin-intolerant and image-piloted strategies may then be helpful to identify patients that need further intensified treatment, e.g., to initiate treatment with proprotein convertase subtilisin / kexin type 9 inhibitors (PCSK9i). In addition, it has also been advocated that statins exhibit nonlipid, cardio-protective effects including improved cardiac nerve integrity, blood flow, and anti-inflammatory effects in congestive heart failure (HF) patients.

Recent Findings

In subjects after myocardial infarction treated with statins, 123II-metaiodobenzylguanidine (MIBG) scintigraphy has already revealed enhanced cardiac nerve function relative to patients without statins. In addition, all of those aforementioned statin-targeted pathways in HF can be visualized and monitored using dedicated cardiac radiotracers, e.g., 123I-MIBG or 18F-AF78 (for cardiac nerve function), 18F-flurpiridaz (to determine coronary flow) or 68Ga-PentixaFor (to detect inflammation).

Statins exhibit various cardio-beneficial effects, including improvement of cardiac nerve function, blood flow, and reduction of inflammation, which can all be imaged using dedicated nuclear cardiac radiotracers. This may allow for in vivo monitoring of statin-induced cardioprotection beyond lipid profiling in HF patients.
Assessment of a dual-frequency multi-GNSS smartphone for surveying applications
Authors: Retscher Guenther , Weigert Till
Published: October 2022

This study assesses the application of a smartphone with dual-frequency multi-constellation GNSS (Global Navigation Satellite Systems) receiver in surveying. Measurements are made with the Pixel 5 from the manufacturer Google LLC. The recorded satellite data is evaluated in post-processing with positioning methods based on code and phase observations. The focus here is led on the achievable positioning accuracies and resulting deviations of the different estimated solutions from reference points serving as ground truth. It could be shown that the Pixel 5, although it enables the recording of satellite data on two frequency bands, can only be used to a limited extent in practical surveying tasks because it does not met the accuracy requirements in the centimetre range in our experiments. The low quality of the measurement data is problematic, which is why solutions over two frequency bands and based on phase observations are only possible to a limited extent. Nevertheless, with long observation times, results with a positioning accuracy of less than half a metre can be achieved with the smartphone. Thus, the Pixel 5 can be used for applications with lower accuracy requirements such as data acquisition for Geographic Information Systems (GIS).
The molluscan assemblage of a pristine Posidonia oceanica meadow in the eastern Mediterranean
Authors: Holzknecht Martina , Albano Paolo G.
Published: October 2022

The seagrass Posidonia oceanica forms extensive meadows in the Mediterranean Sea. Studies on their associated highly diverse invertebrate assemblages are limited to the western Mediterranean. The eastern Mediterranean, however, is a basin undergoing rapid change due to the synergistic effects of climate warming, biological invasions and other human stressors that are driving native biodiversity to regional-scale collapses. We here surveyed the shelled molluscan assemblage of a Posidonia oceanica meadow in Plakias, south-western Crete, the first such study in the eastern Mediterranean Sea. This area has increased its yearly mean temperature by 1 °C in the last 20 years and is under heavy pressure by Lessepsian species. We sampled across a 5- to 20-m depth gradient, in two seasons to capture intra-annual variation and the leaf and rhizome strata separately. Against our expectations, the molluscan assemblage proved to be highly diverse, with species richness, dominant species and trophic guilds comparable to healthy western Mediterranean ones, and with a negligible non-indigenous component. The diversity of the native community (following the biotic resistance hypothesis) and oxygen supersaturation in the meadow may cause greater resistance to biological invasions and warming, respectively, suggesting that Posidonia oceanica meadows may act as a precious refugium for native biodiversity in the fast changing eastern Mediterranean Sea.
“I Am Not the Same as I Was Before”: A Qualitative Analysis of COVID-19 Survivors
Authors: Duan Emily , Garry Kira , Horwitz Leora I. , Weerahandi Himali
Published: October 2022

Background

Little is known about the illness experience of patients’ long-term emotional and physical recovery from severe COVID-19 infection. This study aimed to expand upon the recovery process of COVID-19 survivors up to 6 months after hospital discharge.

Methods

Qualitative analysis of free-response answers from a cohort study of 152 patients ≥ 18 years hospitalized with laboratory-confirmed SARS-CoV-2 surveyed at 1-month post hospital discharge and 6-months post hospital discharge. Responses were analyzed with a grounded theory approach to identify overarching themes.

Results

Participants described persistent complications, both physical and mental, that have affected their recovery from COVID-19. Five overarching themes of post-acute patient experiences were generated: (1) an increased awareness of a mind and body connection, (2) feelings of premature aging, (3) an overall decline in quality of life, (4) a continued fear of infection, and (5) methods of coping.

Conclusions

Patients described lasting changes to their mental health and overall quality of life in connection to physical complications after severe COVID-19 infection. Patients’ reports of their experience call for a greater awareness of the psychological aspects of COVID-19 recovery to provide both physical and psychological rehabilitation services. Additional resources such as education around re-infection and financial resources are needed.
Human body donation and surgical training: a narrative review with global perspectives
Authors: Zdilla Matthew J. , Balta Joy Y.
Published: October 2022

Utilization of human material in surgical simulation training has been well-established as an effective teaching method. Despite the value of donor-based surgical simulation training, its application may be hampered by difficulties regarding access to donated bodies. Therefore, the aim of this review is to assess body donation and body acquisition practices with regard to surgical simulation training programs around the world. The results of this review highlight discrepancies regarding body donation practices and surgical simulation programs among continents and countries. The utilization of donor bodies in surgical simulation appears to mirror body donation practices. In countries that rely mostly or exclusively upon unclaimed bodies or executed criminals, there are scant reports of donor-based surgical simulation programs. In countries where willed-body donation is the principal source of human material, there tend to be many surgical simulation programs that incorporate human material as part of surgical training. This review suggests that, in anatomical and surgical education, the utilization of active willed-body donation programs, as opposed to the utilization of unclaimed human bodies, positively corresponds with the development of beneficial donor-based surgical simulation programs. Likewise, donor-based surgical simulation training programs may have an influence on the perpetualization of willed-body donations.
Effect of n and p-silicon Substrate on Dielectric Constant, Dielectric Loss Tangent of PPy-MWCNTs/TiO2/Al2O3 Structure
Authors: Ashery A. , Gaballah A. E. H.
Published: October 2022

Synthesized these novel structures PPy-MWCNTs/TiO2/Al2O3/p-Si and PPy-MWCNTs/TiO2/Al2O3/n- for using in manufactures diodes, sensor, supercapacitors, and electronic devices. The effect of silicon substrate type on electrical and dielectric parameters such as dielectric constant ɛ`, dielectric loss tangent tanδ, Cole –Cole diagram, the width of the depletion layer (Wd), barrier height (Φb), density state of surface (NSS) and series resistance (Rs) of Au/PPy-MWCNTs/TiO2/Al2O3 were discussed in this work. Researchers frequently alter the composite ratio to increase dielectric characteristics; however, in this study, we use a different approach by altering the type of substrate to improve the dielectric and electric properties of the structure. The sign and magnitude of ɛ` and tanδ are affected by the type of silicon substrate, for example, at frequency 2 × 107 Hz, ɛ` for structure on p-Si has both positive and negative value range (-3500 to 200), whereas ɛ` for structure on n-Si exclusively has negative values (-280 to -220). On the other hand, at the same frequency, tanδ has both positive and negative values (-2 to 8) for structure on p-Si, whilst for n-Si has positive values (0.78 to 0.83). At f = 107 Hz, ɛ` has positive values ranging from (0 to 900) for p-Si substrate while for n-Si, ɛ` has both positive and negative values (-500 to 1500).
Pulse-included diverse crop rotations improved the systems economic profitability: evidenced in two 4-year cycles of rotation experiments
Authors: Khakbazan Mohammad , Liu Kui , Bandara Manjula , Huang Jianzhong , Gan Yantai
Published: October 2022

In the recent past, pulse crops have become increasingly important to agricultural producers as they contribute significantly to the economy. However, the research surrounding the economics of pulse crops is limited. This study determined the net returns and risks of 14 different rotations with various frequencies and sequences of pulse crops and quantified the long-term economic effects. An 8-year field experiment (two 4-year rotation cycles) was carried out at Swift Current, Saskatchewan, and Brooks, Alberta, Canada, during 2010–2019. The crops in the rotation included spring and durum wheat (Triticum aestivum L.) (W), field pea (Pisum sativum L.) (P), chickpea (Cicer arietinum L.) (C), lentil (Lens culinaris Medik) (L), and Oriental mustard (Brassica juncea L.) (M). Net revenue was estimated and a simulation model was used to conduct the risk-return analysis. Net revenue was significantly different among the 14 rotations, where rotations with either high frequencies of lentil or diverse crops generated the highest net income. More diverse rotations such as P-M-L-W or L-C-P-W provided net income that were statistically comparable to the L-L-L-W rotation and were significantly greater than wheat monoculture systems. Risk analysis suggested that neutral or slightly risk averse producers may select rotations with higher frequencies of lentils, whereas more risk averse producers may prefer more diverse rotations. Inclusion of pulses in a rotation as preceding crops had a positive economic impact on the following non-pulse crops and reduced nitrogen cost by 37%, which can lead to a low carbon footprint. Long-term studies with comprehensive datasets are rare and here for the first time we had two full 4-year cycles of experimental data for 14 diverse rotations at three sites, enabling us to make sound conclusions—adopting diverse cropping rotations that include pulses, especially lentil, can reduce economic risks and improve farm profitability.
On the Meaning of Impact in Disaster Risk Reduction
Authors: Alexander David E.
Published: October 2022

This article offers a discussion of the meaning, assessment, and measurement of impact in disaster risk reduction. It begins with a historical perspective on the impact of learned work in times when orthodoxy posed severe limits on the impact of new thinking. Regarding the modern age, the article explains why impact is considered important and how it might be recognized when it occurs, including a tentative classification of types of impact. The question of whether impact can truly be measured remains pending, as the answer is diffuse and dependent on many different circumstances. Further sections consider the relationship between impact and mainstreaming and the question of whether a piece of work should be regarded as having impact if its effects are negative rather than positive. Next, impact is considered in terms of whom it benefits. Given the large number of possible reservations about the concept, the question is raised as to whether too much emphasis is given to the impact of research and scholarship. Finally, some suggestions are offered regarding how to obtain a better indication of what the impact of an academic study actually is.
The Impact of Sex Hormones on the Periodontium During a Woman’s Lifetime: a Concise-Review Update
Authors: Sathish Akanksha Kidiyur , Varghese Jothi , Fernandes Aldridge Jose
Published: October 2022

Purpose of Review

In the field of periodontology, numerous studies have been conducted to observe the effects of sex hormones on the periodontal tissues and the oral mucosa. The balance in the circulating hormonal levels in the female body ensures proper homeostasis of the periodontium. Therefore, this literature review focuses on the more recent concepts related to changes in the endogenous and exogenous female hormones on the periodontal health in the lifetime of a woman.

Recent Findings

Previous studies have reported severe gingival inflammation in women using oral contraceptives. But present day oral contraceptives have decreased dosages in contrast to the older formulations and therefore only mildly affect the periodontium with the majority reporting lack of gingival inflammation. Periodontal treatment strategies for each stage in a woman’s life is also described in this review, and research pertaining to periodontal therapy during pregnancy has shown conflicting results in terms of reducing the risk of adverse pregnancy outcomes.

The changes seen in the periodontium seen in each milestone of a woman’s life correlates to the fluctuating levels in the female sex hormones. Maintaining oral health during the peak of hormone release such as pregnancy helps alleviate the symptoms of periodontal disease as well as reduce the risk of adverse pregnancy outcomes, although studies report conflicting results.
Managing Peer Support Workers in Swedish Mental Health Services—A Leadership Perspective on Implementation and Sustainability
Authors: Grim Katarina , Bergmark Magnus , Argentzell Elisabeth , Rosenberg David
Published: October 2022

Even though it has been demonstrated that peer support contributes to positive outcomes for service users, organizational implementation issues remain. The aim of the current study was to examine an implementation of peer support from the perspective of managers in order to develop knowledge of factors influencing sustainability of this initiative. Eighteen managers were interviewed in connection with the introduction of peer support in sixteen mental health settings. Interviews were analyzed utilizing inductive and deductive approaches. The results suggested that managers were predominantly positive in their evaluation of peer support as a recovery-oriented addition to their services, but noted developmental issues regarding role, professional identity, supervision and financing in relation to other traditional personnel. The involvement of the user movement, especially with regard to training and supervision helped prepare staff and support peer workers, yet there was some apprehension attached to the critical scrutiny that this `outsider’ perspective might imply. The results confirm previously noted uncertainties regarding peer support as an integrated component of mental health systems and illuminate a number of culturally conditioned challenges that may hamper peer support from being implemented with the same approach as other interventions. In response, the present study suggests a number of focus areas that should be attended to in future implementation efforts, including issues related to staff roles, power dynamics, connection to the user movement and reconsideration of the value of experience-based knowledge. In the Swedish context, a government level commitment was identified as critical to ensure stable funding.
How Organizations can Develop Solidarity in the Workplace? A Case Study
Authors: Albert Marie-Noëlle , Lazzari Dodeler Nadia , Ohin Asri Yves
Published: October 2022

The concept of community of persons, which focuses on both persons and the whole, helps understand solidarity. The latter is based on the social nature of persons. Community of persons and solidarity seems to be able to move away from the individualist perspective or the individualism-collectivism dichotomy. Using autopraxeography in a pragmatic constructivism epistemological paradigm, this article aims to explore how organizations can develop solidarity in a workplace. The experience presented takes place in a bank. It shows that communities of persons with employees and customers are both ethical and financially efficient. These communities build a dialogue between persons and organizations. Nevertheless, it is impossible to force solidarity because it could generate derision that is contrary to the wished goal. Finally, while this model is based on solidarity, it focuses solely on internal solidarity.
Why is pet goods consumption imperceptible for economists? A scoping review
Authors: Gromek N. , Perek-Białas J.
Published: October 2022

Nowadays, pets more frequently are becoming family members which deserve certain products and goods, as well as services. In this way, pets are becoming consumers even they do not have a possibility to make decisions (as opposed to human being) as we analyze taking into account human being. Recently pet-related topics are gaining more attention in the press and among researchers in the field of marketing and psychology. Numerous articles regarding pet-related business patterns, like pet insurance, day care and pet friendly hotels are published. No wonder, the popularity of pets among households has been growing for many years. In this article, a scoping review aimed at identifying available studies about expenditures on pet goods and owners’ economic consumption choices has been conducted. A comprehensive search strategy was used across Scopus and EBSCO database. The results show that there is only a few studies concerning pet goods consumption through the lens of economic theories. As such this topic in not explored enough while the market of goods and services is growing.
Prediction and verification of the key ingredients and molecular targets of Guizhi Fuling capsule against tumour metastasis and resistance
Authors: Han Li , Lv Qin , Guo Xiaojuan , Guo Kelei , Du Ruijuan , Li Fubo , Zhao Xulin , Bian Hua
Published: October 2022

Purpose

The well-known traditional Chinese formula Guizhi Fuling capsule (GFC) has been reported to reverse ovarian cancer drug resistance. Extrachromosomal DNA (ecDNA) plays an important role in tumour metastasis and resistance. The purpose of this study was to investigate the potential mechanisms by which GFC blocks tumour metastasis and reverses drug resistance by targeting ecDNA.

Methods

CNKI and PubMed were used to obtain pharmacokinetic research data on GFC in rats, and the bioactive ingredients detected in rat serum or plasma were collected. Network databases were used to screen the abnormally expressed genes in ecDNA, tumour metastasis genes, resistance genes, and the active ingredient targets of GFC. The KOBAS3.0 database was used to enrich the KEGG pathways and GO functions; the STRING platform was used to construct the core protein interaction network; and the molecular docking online tool SwissDock was used to analyse the binding activity of the core targets and the active ingredients. RT-qPCR, Western blotting and laser confocal microscopy were used to verify the effect of the sera containing GFC on ecDNA, mRNA and protein expression of key targets.

Results

Twenty-three bioactive ingredients of GFC were retrieved from PubMed and CNKI. Nine shared targets were simultaneously involved in abnormal genes in ecDNA, tumour metastasis and resistance and the active ingredient targets of GFC. GO functional analysis indicated that the cotargets involved cell proliferation, apoptotic regulation, nuclear functions, etc. The potential pathways involved in the reversal of tumour metastasis and drug resistance of GFC were the PI3K-Akt signalling, cancer, and platinum drug resistance pathways. Three shared proteins targeting ecDNA (AKT1, EGFR and MYC) stand out from the top 20 PPI targets, and all of the bioactive ingredients of GFC have strong binding affinity to the three proteins. The active ingredients can reduce the expression of MYC, EGFR and AKT1 mRNA and protein and the amount of ecDNA in drug-resistant OC cells.

Conclusions

GFC targeting ecDNA to reverse tumour metastasis and drug resistance has the characteristics of multiple ingredients, multiple targets, and multiple pathways, which provides a new perspective for the development of new drugs targeting ecDNA to benefit tumour treatment.
Corruption, Protection and Justice in Medieval Europe
Authors: Lyon Jonathan R.
Published: October 2022

What was an “advocate” (Latin: advocatus; German: Vogt) in the Middle Ages? What responsibilities came with the position and how did they change over time? With this groundbreaking study, Jonathan R. Lyon challenges the standard narrative of a “medieval” Europe of feudalism and lordship being replaced by a “modern” Europe of government, bureaucracy and the state. By focusing on the position of advocate, he argues for continuity in corrupt practices of justice and protection between 750 and 1800. This book traces the development of the role of church advocate from the Carolingian period onward and explains why this position became associated with the violent abuse of power on churches' estates. When other types of advocates became common in and around Germany after 1250, including territorial and urban advocates, they were not officeholders in developing bureaucracies. Instead, they used similar practices to church advocates to profit illicitly from their positions, which calls into question scholarly arguments about the decline of violent lordship and the rise of governmental accountability in European history.
The Experience of God
Authors: Horner Robyn
Published: October 2022

Belief and credal commitment sometimes seem to make less and less sense in the West. A kind of 'cultural amnesia' has taken hold, where formal religious adherence begins to seem almost unthinkable. This is especially so for the idea of divine revelation. Robyn Horner argues this means we need to re-evaluate how theology proceeds, focusing not so much on beliefs but on experience. Exploring ways in which the experiential might open human beings up to divine possibility, the author turns to phenomenology (especially in the French philosophical tradition) because it seeks to examine unrestrictedly what is given through involved encounter. Bringing phenomenology and poststructuralism together, Horner develops the idea of revelation as an 'event' wherein God interrupts and exceeds human experience, affecting and transforming it. This striking concept, named but largely unexplored by theology, articulates a notion of supernatural revelation which now starts to appear both coherent and plausible.
New Testament Theology and the Greek Language
Authors: Porter Stanley E.
Published: October 2022

In this book, Stanley E. Porter offers a unique, language-based critique of New Testament theology by comparing it to the development of language study from the Enlightenment to the present. Tracing the histories of two disciplines that are rarely considered together, Porter shows how the study of New Testament theology has followed outmoded conceptual models from previous eras of intellectual discussion. He reconceptualizes the study of New Testament theology via methods that are based upon the categories of modern linguistics, and demonstrates how they have already been applied to New Testament Greek studies. Porter also develops a workable linguistic model that can be applied to other areas of New Testament research. Opening New Testament Greek linguistics to a wider audience, his volume offers numerous examples of the productivity of this linguistic model, especially in his chapter devoted to the case study of the Son of Man.
Break Free from Maternal Anxiety
Authors: Challacombe Fiona , Green Catherine , Bream Victoria
Published: October 2022

Severe anxiety affects a huge number of women in pregnancy and the postnatal period, making a challenging time even more difficult. You may be suffering from uncontrollable worries about pregnancy and birth, distressing intrusive thoughts of accidental or deliberate harm to the baby, or fears connected to traumatic experiences. This practical self-help guide provides an active route out of feeling anxious. Step-by-step, the book teaches you to apply cognitive behaviour therapy (CBT) techniques in the particular context of pregnancy and becoming a new parent in order to overcome maternal anxiety in all its forms. Working through the book you will gain understanding of your anxiety and how factors from the past and present may be playing a role in how you feel. Together with practical exercises and worksheets to move through at your own pace, you will gain the tools you need to help you move forward and enjoy parenthood.