bluuebunny/crossref_metadata_2025 huggingface dataset:
Preoperative patellofemoral anatomy affects failure rate after isolated patellofemoral inlay arthroplasty
Authors: Feucht Matthias J. , Lutz Patricia M. , Ketzer Conrad , Rupp Marco C. , Cotic Matthias , Imhoff Andreas B. , Pogorzelski Jonas
Published: October 2020

Purpose

To analyze whether preoperative patellofemoral anatomy is associated with clinical improvement and failure rate after isolated patellofemoral arthroplasty (PFA) using a modern inlay-type trochlear implant.

Methods

Prospectively collected 24 months data of patients treated with isolated inlay PFA (HemiCAP®Wave, Arthrosurface, Franklin, MA, USA) between 2009 and 2016, and available digitalized preoperative imaging (plain radiographs in three planes and MRI) were retrospectively analyzed. All patients were evaluated using the WOMAC score, Lysholm score, and VAS pain. Patients revised to TKA or not achieving the minimal clinically important difference (MCID) for the total WOMAC score or VAS pain were considered failures. Preoperative imaging was analyzed regarding the following aspects: Tibiofemoral OA, patellofemoral OA, trochlear dysplasia (Dejour classification), patellar height (Insall–Salvati index [ISI]; Patellotrochlear index [PTI]), and position of the tibial tuberosity (TT–TG and TT–PCL distance).

Results

A total of 41 patients (61% female) with a mean age of 48 ± 13 years could be included. Fifteen patients (37%) were considered failures, with 5 patients (12%) revised to TKA and 10 patients (24%) not achieving MCID for WOMAC total or VAS pain. Failures had a significantly higher ISI, and a significantly lower PTI. Furthermore, the proportion of patients with a pathologic ISI (> 1.2), a pathologic PTI (< 0.28), and without trochlear dysplasia were significantly higher in failures. Significantly greater improvements in clinical outcome scores were observed in patients with a higher preoperative grade of patellofemoral OA, ISI ≤ 1.2, PTI ≥ 0.28, TT–PCL distance ≤ 21 mm, and a dysplastic trochlea.

Conclusion

Preoperative patellofemoral anatomy is significantly associated with clinical improvement and failure rate after isolated inlay PFA. Less improvement and a higher failure rate must be expected in patients with patella alta (ISI > 1.2 and PTI < 0.28), absence of trochlear dysplasia, and a lateralized position of the tibial tuberosity (TT–PCL distance > 21 mm). Concomitant procedures such as tibial tuberosity transfer may, therefore, be considered in such patients.

Level of evidence

Level III, retrospective analysis of prospectively collected data.
The Effects of Intelligence and Personality on Performance in Simulated Interrogation Scenarios
Authors: Morgan Robert , Alison Laurence , Palace Marek , Shortland Neil , Humann Michael
Published: October 2020

The paper explores the relationships between individual differences in intelligence and personality and the ability to extract critical information (and identify missing but required information) from a suspect’s brief sheet (i.e. model formulation) and develop a suitable line of questioning (i.e. approach strategizing) in interrogation scenarios. We hypothesised that cognitive flexibility, emotion management, low need for closure and rapport would all be predictors of these abilities. Two hundred and seventy-four participants of different backgrounds were exposed to two interrogation scenarios to assess model formation and approach strategizing abilities, as well as intelligence and personality tests. Benchmarks for performance were measured against two experienced interrogators and two psychologists’ calibrated performance. In terms of overall performance, only rapport and cognitive flexibility were significant positive predictors. Whereas only rapport was a positive predictor of approach strategizing, both rapport and cognitive flexibility were positive predictors of model formation. In conclusion, the data from the early stage of our project suggests that the examined factors should be carefully considered when training and selecting optimal interrogators. Though previous research has identified a number of individual differences in intelligence and personality that are important in demanding law-enforcement contexts, ours is the first to explore them with respect to effective interrogator performance.
Effects of Conventional and Severe Shot Peening on Residual Stress and Fatigue Strength of Steel AISI 1060 and Residual Stress Relaxation Due to Fatigue Loading: Experimental and Numerical Simulation
Authors: Maleki Erfan , Farrahi Gholam Hossein , Reza Kashyzadeh Kazem , Unal Okan , Gugaliano Mario , Bagherifard Sara
Published: October 2020

This study investigates and compares the effects of different shot peening treatments including conventional and severe shot peening on microstructure, mechanical properties, fatigue behavior, and residual stress relaxation of AISI 1060 steel. Shot peening treatments were applied with two Almen intensities of 17 and 21 A and a wide ranges of coverage (100%–1500%). Various microstructural observations were carried out to analyze the evolution of microstructure. Microhardness, residual stress and surface roughness measurements and also axial fatigue test were performed. Moreover, the extent of the residual stress relaxation during cyclic loading was investigated by means of XRD measurements. Furthermore, numerical simulation of residual stress relaxation due to fatigue loading was carried out and validated against experimental investigations. The comparison indicated a good agreement for the surface residual stress relaxation up to 100 cycles. The experimental results indicated the efficiency of severe shot peening processes in obtaining nanostructured surface layer and achieving superior mechanical properties and fatigue behavior. Also, residual stress measurements revealed that stress relaxation started with a high rate at the initial stages of loading and gradually increased at higher number of cycles which was lower in the case of severely shot peened samples compared to the conventionally treated ones.

Graphic Abstract
Successful rechallenge with cetuximab after an infusion related reaction to panitumumab in a patient with locally advanced rectal cancer
Authors: Yokokawa Hideyuki , Kono Teppei , Shidei Hiroaki , Oyama Kunihiro , Ito Yoshitomo , Imaizumi Rie , Miyano Yutaka , Shiozawa Shunichi , Yoshimatsu Kazuhiko
Published: October 2020

Incidence of infusion related reaction (IR) is more common with cetuximab (Cmab) than with panitumumab (Pmab). Although little is known about rechallenge IR with monoclonal antibodies, we experienced a successful rechallenge to Cmab after IR to Pmab. A 67-year-old female patient was scheduled for chemotherapy with mFOLFOX6 plus Pmab against unresectable advanced rectal cancer in the hope of tumor shrinkage. On the first administration of Pmab, she complained of dyspnea with shortness of breath and wheezing, even after premedication with steroids and antihistamines. Her reaction was judged as Grade 2 IR to Pmab. For the next course, we tried Cmab. No IRs were observed. Since then, she has undergone seven further courses of treatment, followed by surgical resection. The patient benefited from administration of Cmab after experiencing IR to Pmab, suggesting this treatment to be an option for patients of this type who experience IR to Pmab.
Mendelian randomization and pleiotropy analysis
Authors: Zhu Xiaofeng
Published: October 2020

Background

Mendelian randomization (MR) analysis has become popular in inferring and estimating the causality of an exposure on an outcome due to the success of genome wide association studies. Many statistical approaches have been developed and each of these methods require specific assumptions.

Results

In this article, we review the pros and cons of these methods. We use an example of high‐density lipoprotein cholesterol on coronary artery disease to illuminate the challenges in Mendelian randomization investigation.

Conclusion

The current available MR approaches allow us to study causality among risk factors and outcomes. However, novel approaches are desirable for overcoming multiple source confounding of risk factors and an outcome in MR analysis.
Drunkorexia: is it really “just” a university lifestyle choice?
Authors: Griffin Bethany Leigh , Vogt Katharina Sophie
Published: October 2020

Purpose

The current study investigated the prevalence of compensatory behaviours (caloric restriction, increased exercise and bulimic tendencies) in response to alcohol consumption (also known as Drunkorexia) in students, non-students and previous students, as well as beginning to understand the presence of possible predictors of these behaviours (body esteem, sensation seeking).

Methods

A volunteer sample of students, non-students and previous students (n = 95) completed the Compensatory Eating and Behaviours in Response to Alcohol Consumption Scale, a questionnaire which measures overall Drunkorexia engagement. The participants also completed the Body Esteem Scale for Adolescents and Adults Scale (BESAA) and the Brief Sensation Seeking Scale (BSSS) to investigate predictors of Drunkorexia.

Results

The results indicated that there was no significant difference in Drunkorexia engagement and behaviours between students, non-students and previous students. It was also found that both low body esteem and high sensation seeking tendencies were significant predictors of Drunkorexia; specifically, the appearance esteem factor of the BESAA and the disinhibition factor of the BSSS.

Conclusions

Findings suggest that Drunkorexia is also present outside of student populations, and therefore, future interventions and research should include non-students in samples. In addition, findings support the idea that Drunkorexia cannot be classified solely as an eating disorder or a substance abuse disorder. As a result of this, further research should be conducted to fully understand why this complex behaviour exists.

Evidence-based medicine level

III (Evidence obtained from case-control analytic study)
Homologous Strategy to Construct High-Performance Coupling Electrodes for Advanced Potassium-Ion Hybrid Capacitors
Authors: Xu Ying , Ruan Jiafeng , Pang Yuepeng , Sun Hao , Liang Chu , Li Haiwen , Yang Junhe , Zheng Shiyou
Published: October 2020

Potassium-ion hybrid capacitors (PIHCs) have been considered as promising potentials in mid- to large-scale storage system applications owing to their high energy and power density. However, the process involving the intercalation of K+ into the carbonaceous anode is a sluggish reaction, while the adsorption of anions onto the cathode surface is relatively faster, resulting in an inability to exploit the advantage of high energy. To achieve a high-performance PIHC, it is critical to promote the K+ insertion/desertion in anodic materials and design suitable cathodic materials matching the anodes. In this study, we propose a facile “homologous strategy” to construct suitable anode and cathode for high-performance PIHCs, that is, unique multichannel carbon fiber (MCCF)-based anode and cathode materials are firstly prepared by electrospinning, and then followed by sulfur doping and KOH activation treatment, respectively. Owing to a multichannel structure with a large interlayer spacing for introducing S in the sulfur-doped multichannel carbon fiber (S-MCCF) composite, it presents high capacity, super rate capability, and long cycle stability as an anode in potassium-ion cells. The cathode composite of activated multichannel carbon fiber (aMCCF) has a considerably high specific surface area of 1445 m2 g−1 and exhibits outstanding capacitive performance. In particular, benefiting from advantages of the fabricated S-MCCF anode and aMCCF cathode by homologous strategy, PIHCs assembled with the unique MCCF-based anode and cathode show outstanding electrochemical performance, which can deliver high energy and power densities (100 Wh kg−1 at 200 W kg−1, and 58.3 Wh kg−1 at 10,000 W kg−1) and simultaneously exhibit superior cycling stability (90% capacity retention over 7000 cycles at 1.0 A g−1). The excellent electrochemical performance of the MCCF-based composites for PIHC electrodes combined with their simple construction renders such materials attractive for further in-depth investigations of alkali-ion battery and capacitor applications.
Measurement of the air bubble size and velocity from micro air bubble generation (MBG) in diesel using optical methods
Authors: Alfarraj Bader A. , Alkhedhair Abdullah M. , Al-Harbi Ahmed A. , Nowak Wojciech , Alfaleh Saleh A.
Published: October 2020

In this paper, we determine the bubble size and velocity from air bubble generation (MBG) in a diesel using optical methods. A KTM Series Pump was used to generate micro air bubbles in diesel. The air bubble radius and velocity measurements can be useful parameters to optimize the bubble generation process. Two optical systems were used for measurement air bubble sizes and their velocities in diesel. First, the optical system without an objective lens was used to determine the velocity of air bubbles in diesel. Another optical system with a 10× objective lens was used to obtain the size distribution of air bubbles generated in diesel. An available optical system with a 10× objective lens can detect a bubble diameter greater than 3.3 µm that air bubble images were processed using the ImageJ program. We measured the size distribution of air bubbles generated using the ImageJ program. The micro air bubble radius measured in diesel was found to be 6.26 µm in the sample after a month from air bubble generation. In addition, the particle image velocimetry (PIV) technique was used to measure the velocity field. Then, we used the OpenPIV program for PIV image processing. The highest velocity distribution was determined to be 90 mm/s for diesel without air bubbles and 20 mm/s for diesel with air bubbles after a month of the bubble generation.
Political crisis and the Corona—‘State of Emergency’ in Kosovo
Authors: Distler Werner
Published: October 2020

Amidst the arrival of the Coronavirus (SARS-CoV-2) in Kosovo, the new coalition government of Vetevendosje and the Democratic League of Kosovo (LDK) under the leadership of Prime Minister Kurti (Vetevendosje) collapsed after a vote of no confidence on 25 March 2020. On the surface, the vote, initiated by LDK, was the consequence of a conflict over the appropriate Corona strategy. A two-month power struggle under the extraordinary circumstances of Corona-related restriction followed, resulting in a new LDK-led government in early June. The political crisis in Kosovo in the early-phase of Corona has to be analyzed against the background of a political crisis with legacies in the post-conflict period, the polarization between Vetevendosje and other parties, and the strong influence of external actors in Kosovo. In this forum article, I ask how the discourse on the “state of emergency” and the pandemic has influenced power struggles in Kosovo and how the conflicts have challenged the democratic competition and institutions. My main argument is that the pandemic indeed did not lead to any form of cooperation, but the political competitors used the pandemic for an intensification of their power struggle, which—for now—led to the restoration of a government of established elites, supported by diplomatic interventions from external actors.
Vom Protest- zum Quarantänejahr: Neue Arenen der Konfliktaushandlung
Authors: Sydiq Tareq
Published: October 2020

Ob Hong Kong, Arab Spring 2.0, die Proteste in Südamerika oder im Iran, 2019 war ein Jahr globaler Protestbewegungen die insbesondere öffentliche Räume einnahmen. Manche dieser Protestbewegungen konnten schon 2019 Erfolge erzielen oder sich bereits konsolidieren; die meisten jedoch verließen sich darauf, 2020 weiter Druck aufzubauen auf Regierungen. Mit der globalen Pandemie wurde dies fast schlagartig unmöglich gemacht: Kollektive Entscheidungsgewalt, weiterhin eine Domäne der Regierungen, wurde zum entscheidenden Faktor bei der Krisenbekämpfung, auf die partikulär agierende Protestbewegungen keine unmittelbare Antwort hatten. Gleichzeitig fiel der öffentliche Raum als entscheidende Arena für die Austragung dieser Konflikte unter den Beschränkungen der Pandemie-Bekämpfung aus. Protestierende wurden damit aus dem Zentrum des öffentlichen Raumes in die Peripherie gedrängt, wo sie mittels dezentraler Techniken versuchen, Mobilisierungen aufrecht zu erhalten, und in der Pandemiebekämpfung mit staatlichen Institutionen konkurrierten. Während dies den Spielraum von Protestbewegungen einschränkt, erlaubt das Herausbilden neuer Konfliktarenen es ihnen, sich für künftige Protestbewegungen bereit zu halten und staatliche Akteure herauszufordern. Dieses Zeitfenster können Regierende nutzen, um aus effizienter Pandemiebekämpfung Kapital zu schlagen und aus der Interaktion von Institutionen mit AktivistInnen Kooperationen zu erzeugen; ohne aber die zugrundeliegenden Probleme zu lösen, vertagen sich die Protestbewegungen lediglich auf eine Zeit nach der Pandemie.
Computational Fluid Dynamics and its Applications in Echinoderm Palaeobiology
Authors: Rahman Imran A.
Published: October 2020

Computational fluid dynamics (CFD), which involves using computers to simulate fluid flow, is emerging as a powerful approach for elucidating the palaeobiology of ancient organisms. Here, Imran A. Rahman describes its applications for studying fossil echinoderms. When properly configured, CFD simulations can be used to test functional hypotheses in extinct species, informing on aspects such as feeding and stability. They also show great promise for addressing ecological questions related to the interaction between organisms and their environment. CFD has the potential to become an important tool in echinoderm palaeobiology over the coming years.
Promoting sustainable development through trade? EU trade agreements and global value chains
Authors: Poletti Arlo , Sicurelli Daniela , Yildirim Aydin B.
Published: October 2020

Sustainable development provisions have become an integral part of the European Union's (EU's) ‘new generation’ trade agreements. Yet, a growing number of empirical works show that their design varies significantly, even in the trade agreements signed with countries at similar (low) levels of development. We contend that this variation can be accounted for by discussing how the growing integration of the EU economy with specific developing countries across global value chains (GVCs) affects the domestic politics of regulatory export in the EU. European firms that operate within GVCs rely on imports of inputs produced in low-labor cost countries. These firms tend to oppose the export of those regulatory burdens that generate an increase in their imports' variable costs. The political mobilization of these actors weakens domestic coalitions supporting regulatory export strategies, which explains why the EU adopts a more lenient approach over the inclusion of sustainable development provisions in Preferential Trade Agreement negotiations with some developing countries.
THE DEEP PAST OF PRE-COLONIAL AUSTRALIA
Authors: MAWSON STEPHANIE
Published: October 2020

Human occupation of Australia dates back to at least 65,000 years. Aboriginal ontologies incorporate deep memories of this past, at times accompanied by a conviction that Aboriginal people have always been there. This poses a problem for historians and archaeologists: how to construct meaningful histories that extend across such a long duration of space and time. While earlier generations of scholars interpreted pre-colonial Aboriginal history as static and unchanging, marked by isolation and cultural conservatism, recent historical scholarship presents Australia's deep past as dynamic and often at the cutting-edge of human technological innovation. This historiographical shift places Aboriginal people at the centre of pre-colonial history by incorporating Aboriginal oral histories and material culture, as well as ethnographic and anthropological accounts. This review considers some of the debates within this expansive and expanding field, focusing in particular on questions relating to Aboriginal agriculture and land management and connections between Aboriginal communities and their Southeast Asian neighbours. At the same time, the study of Australia's deep past has become a venue for confronting colonial legacies, while also providing a new disciplinary approach to the question of reconciliation and the future of Aboriginal sovereignty in Australia.
Do re-ensiling time and application of Lactobacillus buchneri alter the characteristics of sugarcane silage?
Authors: Faria E. F. S. , da Silva T. C. , Pina D. dos S. , Santos E. M. , de Araújo M. L. G. M. L. , da Silva L. O. , de Carvalho G. G. P.
Published: October 2020

This study aimed to examine the effects of re-ensiling time and Lactobacillus buchneri on the fermentation profile, chemical composition and aerobic stability of sugarcane silages. The experiment was set up as a repeated measure design consisting of four air-exposure periods (EP)(0, 6, 12, and 24 h) microbial additive (A) (L. buchneri; or lack of there), with five replicates. Sugarcane was ground through a stationary forage chopper and ensiled in four plastic drums of 200-L capacity. After 210 days of storage, the drums were opened and half of the silage mass was treated with L. buchneri at the concentration of 105 cfu/g of forage. Subsequently, the silages were divided into stacks. The re-ensiling process was started immediately, at 0, 6, 12 and 24-hour intervals, by transferring the material to PVC mini-silos. Silos were opened after 120 days of re-ensiling. The use of L. buchneri reduced butyrate concentration but did not change ethanol or acetic acid concentrations and aerobic stability. An interaction effect between L. buchneri and re-ensiling time was observed for dry matter (DM) losses and composition. Lactobacillus buchneri is not effective in improving aerobic stability in re-ensiled sugarcane silages. However, less DM is lost in silages treated with L. buchneri and exposed to air for 24 h. Re-ensiling sugar cane in up to 24 h of exposure to air does not change final product quality.
A discrepancy version of the Hajnal–Szemerédi theorem
Authors: Balogh József , Csaba Béla , Pluhár András , Treglown Andrew
Published: October 2020

A perfect Kr-tiling in a graph G is a collection of vertex-disjoint copies of the clique Kr in G covering every vertex of G. The famous Hajnal–Szemerédi theorem determines the minimum degree threshold for forcing a perfect Kr-tiling in a graph G. The notion of discrepancy appears in many branches of mathematics. In the graph setting, one assigns the edges of a graph G labels from {‒1, 1}, and one seeks substructures F of G that have ‘high’ discrepancy (i.e. the sum of the labels of the edges in F is far from 0). In this paper we determine the minimum degree threshold for a graph to contain a perfect Kr-tiling of high discrepancy.
Emergency department utilisation and critical readmission in patients with Fontan circulation
Authors: Cashen Katherine , Petersen Tara L. , Rood Cailyn , Cater Daniel , Waslawski Sheila F. , Slaven James E. , Mastropietro Christopher W.
Published: October 2020

Background:

We aimed to conduct a multi-centre study characterising emergency department utilisation and critical readmissions experienced by children with Fontan circulation.

Methods:

We conducted a retrospective review of children who underwent the Fontan operation at three institutions (i.e., centres A, B, and C) between 2009 and 2014, with follow-up through December 2015. Multi-variable analyses were performed to determine factors associated for emergency department utilisation within 1 year of surgery, emergency department utilisation at any time following surgery, or critical readmission (defined as admission to ICU, operating room, or cardiac catheterisation).

Results:

We reviewed 297 patients, of which 147 patients (49%) had 607 emergency department encounters. Forty-six patients (15%) required 71 critical readmissions. Multi-variable analyses revealed centre C (p = 0.02) and post-operative hospitalisation ≥ 14 days (p = 0.03) to be significantly associated with emergency department utilisation within 1 year, whereas centre B (p < 0.001), post-operative hospitalisation ≥ 14 days (p = 0.002), and African-American/Black race (p = 0.04) were significantly associated with critical readmission.

Conclusions:

In this multi-centre study, nearly half of patients with Fontan circulation received emergency department care, often presenting with high disease acuity requiring readmission. Emergency department utilisation and need for critical readmission were independently influenced by the centre at which surgery was performed, prolonged post-operative hospitalisation, and racial background. These data could help guide quality improvement efforts aimed at reducing morbidity in this unique patient population.
Association of MnSOD gene polymorphism with susceptibility to Kawasaki disease in Chinese children
Authors: Wu Jiping , Yu Meng , Huang Lihua , Qian Yujie , Kong Min , Kang Zhijuan , Yang Zuocheng
Published: October 2020

Background:

Kawasaki disease is a type of acute febrile rash disease that is common in children and is characterised by primary lesions of systemic middle and small vasculitis, which can lead to coronary artery lesions. Manganese superoxide dismutase (MnSOD), one of the most important antioxidases in the human body, plays a key role in maintaining the balance of free radicals in the human body. Two single-nucleotide polymorphisms (SNPS) (rs4880 and rs5746136) in the MnSOD gene were related to oxidative stress disease. The purpose of this study is to explore the possible relationship between MnSOD gene polymorphisms and Kawasaki disease susceptibility.

Methods:

This study included 100 Kawasaki disease children and 102 healthy children. Two single-nucleotide polymorphisms (rs4880 and rs5746136) were detected by polymerase chain reaction sequence-based typing.

Results:

There was a significant difference in both the genotype frequency (χ2 = 10.805, p = 0.005) and the allele frequency (χ2 = 7.948, p = 0.005) of rs5746136 between the Kawasaki disease group and the control group. Children with the A allele had a 0.558 times lower risk of Kawasaki disease than those without the A allele (χ2 = 7.948, p = 0.005, odds ratio = 0.558, 95% confidence interval = 0.371–0.838). There was no significant difference in the genotype and gene frequencies of rs5746136 between the Kawasaki disease-coronary artery lesion and Kawasaki disease-without coronary artery lesion groups (p > 0.05), and there was no significant difference in the rs4880 genotype and allele frequencies between the Kawasaki disease and healthy control groups or between the Kawasaki disease-coronary artery lesion and Kawasaki disease-without coronary artery lesions groups (p > 0.05).

Conclusion:

This study provides evidence supporting an association between MnSOD gene polymorphisms and susceptibility to Kawasaki disease. The genotype AA and the allele A of the MnSOD gene locus rs5746136 were risk factors for Kawasaki disease.
ECMO Transport without Physicians or Additional Clinicians
Authors: Condella Anna , Richards Jeremy B. , Frakes Michael A. , Grant Christian J. , Cohen Jason E. , Wilcox Susan R.
Published: October 2020

Background:

Extracorporeal membrane oxygenation (ECMO) has accelerated rapidly for patients in severe cardiac or respiratory failure. As a result, ECMO networks are being developed across the world using a “hub and spoke” model. Current guidelines call for all patients transported on ECMO to be accompanied by a physician during transport. However, as ECMO centers and networks grow, the increasing number of transports will be limited by this mandate.

Objectives:

The aim of this study was to compare rates of adverse events occurring during transport of ECMO patients with and without an additional clinician, defined as a physician, nurse practitioner (NP), or physician assistant (PA).

Methods:

This is a retrospective cohort study of all adults transported while cannulated on ECMO from 2011-2018 via ground and air between 21 hospitals in the northeastern United States, comparing transports with and without additional clinicians. The primary outcome was the rate of major adverse events, and the secondary outcome was minor adverse events.

Results:

Over the seven-year study period, 93 patients on ECMO were transported. Twenty-three transports (24.7%) were accompanied by a physician or other additional clinician. Major adverse events occurred in 21.5% of all transports. There was no difference in the total rate of major adverse events between accompanied and unaccompanied transports (P = .91). Multivariate analysis did not demonstrate any parameter as being predictive of major adverse events.

Conclusions:

In a retrospective cohort study of transports of ECMO patients, there was no association between the overall rate of major adverse events in transport and the accompaniment of an additional clinician. No variables were associated with major adverse events in either cohort.
OPPOSING AND POLICING RACIAL INTEGRATION
Authors: Kurwa Rahim
Published: October 2020

Over fifty years after the passage of the Fair Housing Act, how have mechanisms of residential segregation changed? Using a case study of a Los Angeles suburb’s reaction to Black movement through the federal Housing Choice Voucher program, I argue that policing should be considered among the contemporary forces of residential segregation. Through interviews with forty-three local residents, I show how one community’s reaction to voucher movement spans from attitudes to actions. First, I document widespread hostility towards Black voucher holders on the basis of their race, gender, and participation in the voucher program. Second, I trace how the city’s municipal code changes have responded to public sentiment and created an incentive to participate in policing. By attaching fines and incentives for landlords to evict tenants to broadly written and subjective nuisance codes, the city has created a pathway by which local residents can pressure unwanted neighbors out of the community. Third, I illustrate how some residents engage in participatory policing by surveilling neighbors they believe are using vouchers and dispatching city and police agencies to inspect, fine, and possibly evict these targets. These findings illustrate how communities can use policing to racially segregate space, how eviction might be communally produced, and how local opposition to Black movement breaks the pathway between residential mobility and socio-economic gains that underlies the voucher program.
Ever failed. No matter. Try again. Fail again. Fail better: IR theory, utopia, and a failure to (re)imagine failure
Authors: Gabay Clive
Published: October 2020

Important scholarship in International Relations (IR) theory engages with the utopian tradition in order to render it ‘realistic’, whereby ‘failed’ utopian projects become necessarily unrealistic, and anti-political. The paper suggests such scholarship is informed by a narrow chronotic register, and a dichotomous ontology of chronos and kairos derived in part from the work of Karl Mannheim and E.H. Carr. As such, utopian scholarship in IR constructs a self-reinforcing relationship between change and realism, whereby only ‘realistic’ interventions can affect normatively desirable change, and therefore only interventions that are possible under current social and political conditions are normatively desirable. Drawing on the idea that the quest for utopia must always fail, the paper suggests that IR theory should be far more attuned to ‘failure’ than as simply a phenomenon that helps define the boundary between the realistic and unrealistic. The paper draws on non-canonical literatures from utopian studies and anarchism, to furnish an alternative ‘no-point’ form of utopianism that dissolves the chronos/kairos binary and thus engages neither in universalist and violent end-point, nor institutionally compromised ‘mid-range’ utopianism. This acts to reconceptualise ‘failure’ in excess of itself, a productive site for IR scholarship, and a political archive for movements and struggles to learn from.
Making Infrastructure ‘Visible’ in Environmental Law: The Belt and Road Initiative and Climate Change Friction
Authors: Bogojević Sanja , Zou Mimi
Published: October 2020

Infrastructure is often viewed through global and promotional lenses, particularly its role in creating market connectivity. However, infrastructure is heavily dependent on and constitutive of local spaces, where ‘frictions’, or disputes, emerge. Drawing on the Belt and Road Initiative (BRI) as a case study, we examine in detail two cases of BRI-related climate change litigation – one in Pakistan, and one in Kenya – that shed light on the frictions arising from what is deemed the most significant transnational infrastructure project of our time. In doing so, this study demonstrates how infrastructure can be made more visible in environmental law and how environmental law itself provides an important mechanism for stabilizing friction in the places where infrastructure is located.
Determinants of Suicidal Ideation among Older Adults
Authors: Foroughan Mahshid , Rostami Mohammad , Jalal Younesi Seyed
Published: October 2020

Abstract. This study examined the relationship of depression and life satisfaction with suicidal ideation among older Iranian adults. In this cross-sectional study, a total of 159 older adults in Tehran (73% community-residing, 60 years or older) participated. The data were gathered using the Beck Scale for Suicidal Ideation (BSSI), the Geriatric Depression Scale (GDS), and the Life Satisfaction Index-Z (LSIZ). According to the results, depression and life satisfaction are significantly related to suicidal ideation; the two variables predict 0.39% of the variance of suicidal ideation in older adults ( p < .01). The interaction between depression and life satisfaction is a stronger predictor of suicidal ideation in older adults than each of the variables alone.
Experience Matters
Authors: Mendes Pedro S. , Luna Karlos , Albuquerque Pedro B.
Published: October 2020

Abstract. The present study tested if word frequency effects on judgments of learning (JOLs) are exclusively due to beliefs or if the direct experience with the items also plays a role. Across four experiments, participants read prompts about the frequency of the words (high/low), which could be congruent/incongruent with the words’ actual frequency. They made pre-study JOLs (except Experiment 1b), immediate JOLs, and completed a recall test. If experience drives the effect, JOLs should be based on actual word frequency rather than the prompts. Results showed higher pre-study JOLs for prompts of high frequency, but higher immediate JOLs for high-frequency words regardless of the prompt, suggesting an effect of direct experience with the words. In Experiments 2 and 3, we manipulated participants’ beliefs, finding a small effect of beliefs on JOLs. We conclude that, regarding word frequency, direct experience with the items seems more relevant than beliefs when making immediate JOLs.
Reactivity of Judgments of Learning in a Levels-of-Processing Paradigm
Authors: Tekin Eylul , Roediger Henry L.
Published: October 2020

Abstract. Recent studies have shown that judgments of learning (JOLs) are reactive measures in paired-associate learning paradigms. However, evidence is scarce concerning whether JOLs are reactive in other paradigms. In old/new recognition experiments, we investigated the reactivity effects of JOLs in a levels-of-processing (LOP) paradigm. In Experiments 1 and 2, for each word, subjects saw a yes/no orienting question followed by the target word and a response. Then, they either did or did not make a JOL. The yes/no questions were about target words’ appearances, rhyming properties, or category memberships. In Experiment 3, for each word, subjects gave a pleasantness rating or counted the letter “e ”. Our results revealed that JOLs enhanced recognition across all orienting tasks in Experiments 1 and 2, and for the e-counting task in Experiment 3. This reactive effect was salient for shallow tasks, attenuating – but not eliminating – the LOP effect after making JOLs. We conclude that JOLs are reactive in LOP paradigms and subjects encode words more effectively when providing JOLs.
Louder = Larger = Clearer
Authors: Kuhlmann Beatrice G. , Frank David J. , Danner Daniel
Published: October 2020

Abstract. Past research found robust metamemory illusions about the effects of font type, word-pair identity, volume, and font size on memory that are assumed to share a common cause, such as fluency. The current study simultaneously assessed all four metamemory illusions from vignettes alongside items assessing the belief that fluency benefits memory and that more is generally better. The typical metamemory illusions replicated in all samples. Confirmatory factor and structural equation modeling confirmed that at least the perceptual metamemory illusions (font type, volume, font size) can be explained by one latent factor, which was, however, not related to latent factors capturing the belief that fluency benefits memory or that more is better.
The "Complicated" Complexity of Solar Storms
Authors: Thompson Elizabeth
Published: October 2020

Researchers turned to crowdsourced science to identify patterns in coronal mass ejections.
On the Impact of a Streaming Oxygen Population on Collisionless Magnetic Reconnection
Authors: Kolstø Håkon Midthun , Hesse Michael , Norgren Cecilia , Tenfjord Paul , Spinnangr Susanne Flø , Kwagala Norah
Published: October 2020

Using 2.5‐D Particle‐In‐Cell (PIC) simulations, we investigate how magnetotail reconnection is affected by a cold, streaming, oxygen plasma population, attributed to an ionospheric source, in the inflow region. As the tailward streaming oxygen reaches the current layer, a tailward motion of the reconnection site is induced. Due to the much longer cyclotron period of the oxygen ions, oxygen cannot couple as directly into the reconnection dynamics as protons. We find that the oxygen ions couple indirectly by means of impacting the electron dynamics. Therefore, a demagnetized species can, in fact, alter the dynamics of the reconnection site. We see further that the reconnection rate remains unchanged relative to a nonstreaming run. Our results may prove useful for understanding the development and dynamics of magnetospheric substorms and storms.
Hydrologic Properties of a Highly Permeable Firn Aquifer in the Wilkins Ice Shelf, Antarctica
Authors: Montgomery Lynn , Miège Clément , Miller Julie , Scambos Ted A. , Wallin Bruce , Miller Olivia , Solomon D. Kip , Forster Richard , Koenig Lora
Published: October 2020

We present measurements of the density, hydraulic conductivity, and specific discharge of a widespread firn aquifer in Antarctica, within the Wilkins Ice Shelf. At the field site, the aquifer is 16.2 m thick, starting at 13.4 m from the snow surface and transitioning from water‐saturated firn to ice at 29.6 m. Hydraulic conductivity derived from slug tests show a geometric mean value of 1.4 ± 1.2 × 10−4 m s−1, equivalent to permeability of 2.6 ± 2.2 × 10−11 m2. A borehole dilution test indicates an average specific discharge value of 1.9 ± 2.8 × 10−6 m s−1. Ground‐penetrating radar profiles and a groundwater flow model show the aquifer is draining laterally into a large nearby rift. Our findings indicate that the firn aquifer in the vicinity of the field site is likely not in a steady state and its presence likely contributed to past ice shelf instability.
Intraseasonal Predictions for the South American Rainfall Dipole
Authors: Díaz Nicolás , Barreiro Marcelo , Rubido Nicolás
Published: October 2020

The South American rainfall Dipole (SAD) is a renowned spatial structure present in the austral summer as part of the South American monsoon system. SAD phases have been related with extreme precipitations and severe droughts across South America, but are yet to be predicted. Here, we reveal two robust and reliable intraseasonal windows in the accumulated SAD index where we can forecast its quantile‐state between 5 to 15 and 60 to 70 days in advance (99% significance level). These windows are insensitive to variations in the pole's size and accumulation window, and results are consistent across different quantiles states (median, tercile, and quartile). Our method, which is based on analyzing the lagged mutual information between future and present states, could be used in the development of early warnings for extreme rainfall events. Moreover, it is unrestricted to the present analysis, being applicable to other stationary signals where a forecast is missing.
Identification of Potential Mantle Rocks Around the Lunar Imbrium Basin
Authors: Bretzfelder Jordan M. , Klima Rachel L. , Greenhagen Benjamin T. , Buczkowski Debra L. , Petro Noah E. , Day Mackenzie
Published: October 2020

Basin‐forming impacts expose material from deep within the interior of the Moon. Given the number of lunar basins, one would expect to find samples of the lunar mantle among those returned by the Apollo or Luna missions or within the lunar meteorite collection. However, only a few candidate mantle samples have been identified. Some remotely detected locations have been postulated to contain mantle‐derived material, but none are mineralogically consistent upon study with multiple techniques. To locate potential remnants of the lunar mantle, we searched for early‐crystallizing minerals using data from the Moon Mineralogy Mapper (M3) and the Diviner Lunar Radiometer (Diviner). While the lunar crust is largely composed of plagioclase, the mantle should contain almost none. M3 spectra were used to identify massifs bearing mafic minerals and Diviner was used to constrain the relative abundance of plagioclase. Of the sites analyzed, only Mons Wolff was found to potentially contain mantle material.
Carbon Dioxide Emissions During the 2018 Kilauea Volcano Eruption Estimated Using OCO‐2 Satellite Retrievals
Authors: Johnson Matthew S. , Schwandner Florian M. , Potter Christopher S. , Nguyen Hai M. , Bell Emily , Nelson Robert R. , Philip Sajeev , O'Dell Christopher W.
Published: October 2020

This study applies Orbiting Carbon Observatory‐2 (OCO‐2) column‐averaged dry‐air mole fractions of CO2 (XCO2) to constrain CO2 fluxes during the 2018 Kilauea volcano eruption. CO2 enhancements (ΔXCO2) of 1–2 parts per million were observed far downwind of the eruption coincident with elevated sulfur dioxide (SO2) concentrations. The estimated CO2 emission rate was 77.1 ± 49.6 kilotons per day (kt day−1) on 11 July 2018 with most of the uncertainty from modeled winds and XCO2 retrievals. This emission rate is higher compared to flux estimates made with ground‐based measurements (30–40 kt day−1). However, cross‐sectional flux estimates made using OCO‐2 XCO2 observations will inherently be larger than ground‐based measurements near the source as these estimates comprise all sources of CO2 in the vicinity of the eruption (e.g., vegetation and soil burning). This study for the first time uses satellite XCO2 data ~200 km downwind to estimate CO2 emissions from a major volcanic eruption.
Hydroclimatic Controls on Salt Fluxes and Halite Deposition in the Dead Sea and the Shaping of “Salt Giants”
Authors: Sirota Ido , Ouillon Raphael , Mor Ziv , Meiburg Eckart , Enzel Yehouda , Arnon Ali , Lensky Nadav G.
Published: October 2020

As the only deep hypersaline, halite‐precipitating lake on Earth today, the Dead Sea is the single modern analog for investigating the mechanisms by which large‐scale and thick salt deposits, known as “salt giants”, have accreted in the geological record. We directly measure the hydroclimatic forcing and the physical limnologic processes leading to halite sedimentation, the vertical thermohaline structure, and salt fluxes in the Dead Sea. We demonstrate that changes in these forcing lead to strong seasonal and regional variations in the stratification stability ratio, triggering corresponding spatiotemporal variations in thermohaline staircase formation and diapycnal salt flux, and finally control the thickness of the halite layer deposited. The observed staircase formation is consistent with the mean‐field γ instability, causing layering in double‐diffusive convection. We show that double diffusion and thermohaline staircase formation drive the spatial variability of halite deposition in hypersaline water bodies, underlying and shaping “salt giants” basin architecture.
Enhanced Dehydration Weakening of Antigorite Driven by Slow Shear Heating: Insights From High‐Pressure Experiments With a Modified Apparatus Stiffness
Authors: Burdette Eric , Hirth Greg
Published: October 2020

Deformation experiments were conducted to investigate the influence of apparatus stiffness on frictional stability during dehydration of antigorite. These experiments also provided a novel way to constrain relationships between fault slip rate and reaction weakening. Experiments were conducted at a confining pressure of 1 GPa using a Griggs apparatus with a modified loading column. During experiments, the temperature was ramped from 400°C to 700°C over 600 seconds, while deformation was imposed with varying load‐point displacement rates. No stick‐slip behavior was observed during the experiments, despite an order of magnitude lower apparatus stiffness, suggesting there are inherent differences in the frictional stability between low pressure (where stick‐slip is observed during dehydration) and high pressure experiments. Fault slip at high pressure may be stabilized by higher dehydration temperatures and higher shear stresses prior to the onset of dehydration reactions. In comparison to reference experiments conducted with an unmodified stiffness, the weakening rate during dehydration increases by a factor of two. In addition, the time (and therefore imposed temperature) at which the maximum weakening rate is observed decreases linearly with increasing maximum weakening rate. Microstructures in the deformed samples illustrate much greater reaction extents (locally >50%) relative to the reference experiments (<1%), with decreasing reaction extent away from the primary slip surfaces. These observations indicate that the dehydration reaction is enhanced by additional shear dissipation resulting from a tenfold increase in displacement per increment of weakening. The shear‐enhanced reaction mechanism could potentially generate runaway slip in subduction zone settings, leading to intermediate‐depth earthquakes.
DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells
Authors: Zhao Fei , Kim Wootae , Kloeber Jake A. , Lou Zhenkun
Published: October 2020

DNA end resection has a key role in double-strand break repair and DNA replication. Defective DNA end resection can cause malfunctions in DNA repair and replication, leading to greater genomic instability. DNA end resection is initiated by MRN-CtIP generating short, 3′-single-stranded DNA (ssDNA). This newly generated ssDNA is further elongated by multiple nucleases and DNA helicases, such as EXO1, DNA2, and BLM. Effective DNA end resection is essential for error-free homologous recombination DNA repair, the degradation of incorrectly replicated DNA and double-strand break repair choice. Because of its importance in DNA repair, DNA end resection is strictly regulated. Numerous mechanisms have been reported to regulate the initiation, extension, and termination of DNA end resection. Here, we review the general process of DNA end resection and its role in DNA replication and repair pathway choice.