Study on Patients’ Adaptation in Sanatoriums
Authors: Lobanov Andrey A. , Andronov Sergey V. , Fesyun Anatoliy D. , Rachin Andrey P. , Grishechkina Irina A. , Popov Andrey I. , Yakovlev Maksim Yu. Yakovlev , Nikitin Mikhail V. , Lebedeva Olga D. 
Published: July 2021

There are indications, contraindications and risks of the climatotherapy application. The impact of weather factors on the human body during the period of sanatorium-resort treatment is not only able to trigger the mechanisms of sanogenesis, but also cause a breakdown in adaptation and a deterioration in the course of cardiovascular diseases. According to various domestic sources, pronounced weather sensitivity is observed in 80-85% of patients with common diseases of the circulatory system. Aim. To assess the influence of biotropic weather conditions on the occurrence of exacerbation and progression of meteorological diseases of the circulatory system associated with the passage of sanatorium-resort treatment in another region, in order to draw up a personalized forecast of the exacerbations progression as well as to develop programs for the prevention and treatment of weatherdependent circulatory system diseases. Material and methods. Two series of studies were conducted on a single patient population: a study of adaptation depending on the climatic conditions of the residence region r(n=200) and a retrospective study on symptoms – weather events linkage, the relationship of symptoms with a region of sanatorium-resort treatment (n=148). Designs of retrospective and longitudinal prospective clinical trials were used. To evaluate the presence of weather factors and patient complaints linkage, the method of hierarchical agglomerative clustering was used. The ARIMA moving variable method was used to assess risks and build predictive models. Results. The greatest impact on the well-being of patients with hypertension treated in Sanatorium and Resort Complex «Vulan», a scientific and clinical branch of the National Medical Research Center of Rehabilitation and Balneology, are rapid changes in atmospheric pressure (1.7 points out of 3 maximums possible) and temperature (1.3 points), “magnetic storms” (1.9 points), as well as high atmospheric pressure (1.2 points), the least influence is frost (0.2 points) and snow (0.1 points). Patients with essential hypertension who came to undergo sanatorium-resort treatment in the Southern Federal District (FD) (Gelendzhik) showed pronounced adaptive changes, manifested in an increase in the amplitude of changes in subjective indicators from 3-5 to 10-14 days of treatment. Adaptation of patients who arrived from the Central FD and the Ural FD was distinguished by the onset of the adaptive changes peak on the 3 day and attenuation of adaptive reactions by 10-14th days. In patients coming from the Southern FD, the adaptive reactions were poorly expressed, had no significant peaks and subsided on 10-14th days. Conclusion. The severity of meteopathic reactions depends on the region of the patient’s residence, the region of the sanatoriumresort treatment, the duration of the patient’s staying in the resort area. The questionnaire and the self-control diary developed in the course of the study allow an adequate assessment of the meteorological factors influence on the human body.