bluuebunny/crossref_metadata_2025 huggingface dataset:
Prospective Analysis of Wound Infection Following Cesarean Section
Authors: Shukkur Sahrun Al , Rao Bharathi , Zubair Sabah Mohd
Published: September 2020

Background: To study the risk factors among women who develop postoperative wound infection following caesarean section, and to analyze the microbiological pattern and antibiotic sensitivity. Method: This prospective hospital-based cross-sectional study conducted in government Lady Goschen Hospital, Mangalore, between October 2016 to March 2018, enrolled women who developed surgical site infections (SSI) within 30 days of caesarean delivery performed in the hospital. Descriptive statistics were used for socio-demographic variables and appropriate univariate and multivariate analysis used to find the association between continuous and categorical variables with a p-value of <0.05 taken as statistically significant.Results: Out of 4540 cesarean deliveries, 52 (1.1%) cases developed SSI. Surgical site infections were found significantly associated with maternal age above 25years, BMI>27Kg/m2 (p<0.001), hypertension, diabetes (p<0.001), the urgency of caesarean delivery, prolonged operative duration, technique and suture material (p<0.001) used. Poliglecaprone (monofilament) was found suitable for subcutaneous tissue and skin closure. Out of 38 cases with microbial growth, 52% cultured Staphylococcus aureus with 60% displaying methicillin resistance, followed by Diphtherioids (22%) and Pseudomonas (10.5%). Majority isolates showed higher sensitivity to Linezolid, Clindamycin and Vancomycin.Conclusion: Apart from maternal factors, the surgeon’s operative skill & technique, and suture material also contribute significantly to the development of SSI. A developing trend towards resistance to higher antibiotics was noted among Methicillin-resistant Staphylococcus aureus. Gentamicin and Linezolid were found as effective as second-line agents. Hence maintenance of quality asepsis and a hospital-based antibiotic policy is vital.
A HEVC Steganalysis Algorithm Based on Relationship of Adjacent Intra Prediction Modes
Authors: Shi Henan , Sun Tanfeng , Li Zhaohong
Published: September 2020

Currently, many High Efficiency Video Coding (HEVC) video steganography algorithms based on Intra Prediction Mode (IPM) have been proposed. However, the existing IPM-based video steganalysis algorithms are almost designed for H.264/AVC videos, without considering the unique coding techniques in HEVC, which is the latest video codec standard. Thus, it is of significant value to study IPM-based steganalysis for HEVC videos. In this paper, the general process of IPM-based HEVC steganography is modelled for the first time, and we find that the basic distortion existing in the change of the relationships between each embedded IPM and the adjacent IPMs. By exploiting these weaknesses, we propose a novel IPM steganalysis algorithm based on the Relationship of Adjacent IPMs (RoAIPM) feature. In detail, the RoAIPM is extracted by generating different directional Gray-Level Co-occurrence Matrixes (GLCMs) and texture characteristics of three refilled matrixes: MPM-IPM matrix, Left-IPM matrix and Up-IPM matrix. Experimental results show that, the proposed RoAIPM feature is very sensitive to the little change introduced by IPM-based steganography. Regardless of whether the feature is after dimension reduction or not, in various coding conditions, the proposed steganalysis can both present a well higher detection accuracy against the latest IPM-based HEVC steganography methods and achieve the lowest computational complexity compared with the state-of-the-art works.
Integrated DNA Methylation and Gene Expression Analysis Identified S100A8 and S100A9 in the Pathogenesis of Obesity
Authors: Chen Ningyuan , Miao Liu , Lin Wei , Zhou Dong-Hua , Huang Ling , Huang Jia , Shi Wan-Xin , Li Li-Ling , Luo Yu-Xing , Liang Hao , Pan Shang-Ling , Peng Jun-Hua
Published: September 2020

Background: To explore the association of DNA methylation and gene expression in the pathology of obesity.Methods: (1) Genomic DNA methylation and mRNA expression profile of visceral adipose tissue (VAT) were performed in a comprehensive database of gene expression in obese and normal subjects; (2) functional enrichment analysis and construction of differential methylation gene regulatory network were performed; (3) Validation of the two different methylation sites and corresponding gene expression was done in a separate microarray data set; and (4) correlation analysis was performed on DNA methylation and mRNA expression data.Results: A total of 77 differentially expressed mRNA matched with differentially methylated genes. Analysis revealed two different methylation sites corresponding to two unique genes-s100a8-cg09174555 and s100a9-cg03165378. Through the verification test of two interested different expression positions (DMPS) and their corresponding gene expression, we found that the methylation in these genes was negatively correlated to gene expression in the obesity group. Higher S100A8 and S100A9 expression in obese subjects were validated in a separate microarray data set.Conclusion: This study confirmed the relationship between DNA methylation and gene expression and emphasized the important role of S100A8 and S100A9 in the pathogenesis of obesity.
A Rare EGFR R748T Mutation in A Squamous Cell Lung Carcinoma Patient with PD-L1 High Expression and Response to Immuno-Chemo Combination Therapy
Authors: Sun Ruifang , Duan Qianqian , Lei Guangyan , Liu Zhigang
Published: September 2020

Background: In present, patients with stage IV or recurrent/metastatic non-small cell lung cancer (NSCLC) whose tumors harbor programmed death ligand 1 (PD-L1) expression and active Epidermal Growth Factor Receptor (EGFR) mutations should receive initial EGFR tyrosine kinase inhibitors (TKIs) based on clinical guidelines and practice. However, high PD-L1 expression correlates with primary resistance to EGFR-TKIs in treatment advanced EGFR-mutant lung cancer patients, the optimal use of ICI therapy in patients with actionable EGFR mutations remains an important field of ongoing research. Some studies also showed that patients with uncommon EGFR mutations have a good immunotherapy potential.Case prestation: Here, we report a 56-year old advanced squamous cell lung carcinoma (SCC) patient with a rare active mutation in EGFR gene (EGFR p.R748T) and PD-L1 expression who responded well to the immune-chemo combination therapy (pembrolizumab with nab-paclitaxel and nedaplatin). Conclusion: The EGFR R748T mutation is an uncommon active mutation and there is no report about immuno-chemo therapy on patient with EGFR R748T mutation and PD-L1 high expression. The result presented in this case provides a feasible therapy for some patients who harbor rare active EGFR mutations (except for G719X, L861Q, S768I, and Ex20 ins) with high PD-L1 expression.
Effects of Discontinuing Contact Precaution on Control of Extended-Spectrum β-lactamase-producing Enterobacteriaceae Nosocomial Acquisition: An Interrupted Time Series Analysis
Authors: Regad Marie , Renaudin Laurie , Lizon Julie , Levy Bruno , Jacquet Caroline , Florentin Arnaud
Published: September 2020

Background:

Interest of contact precautions (CP) to prevent cross-transmission in addition to standard precautions (SP) is actually debated in the literature for some microorganisms, like extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBLE). We took advantage of the decision to stop CP for ESBLE in our hospital to study in real life if this discontinuing has an impact on the ESBLE acquisition rate.
Methods:

An interrupted time series (ITS) was performed in 3 wards and the week was used as the temporal unit. The ESBLE acquisition and importation incidence density (ID) and potential risks factors (colonization and selective pressure, Alcohol-Based hand rub solution consumption rates, demographic patients data) were collected between two periods: the pre-intervention (July 2018 to June 2019) when patients infected or colonized by ESBLE were cared with PC and SP and the post-intervention (September 2019 to March 2020) when patients were cared with SP only.
Results:

ESBLE acquisition ID were of 1.32 ± 1.36 and 1.17 ± 1.25 cases per 1000 patient-days for the pre- and post-intervention period respectively with no significant change in slope (p = 0.15). The only confounding variable significant (p = 0.04) in ITS was the antibiotics consumption, with a positive increasing trend.
Conclusion:

This study showed that the SP alone in order to control the ESBLE nosocomial did not lead to increasing the ESBLE nosocomial cross-transmission.
Upregulating CXCR7 Accelerates Endothelial Progenitor Cells Mediated Endothelial Reparation via Activating Akt/Keap-1/Nrf2 Signaling in Diabetes Mellitus
Authors: Jiang Chunyu , Li Ruiting , Xiu Chaoyang , Ma Xu , Hu Hui , Wei Liming , Tang Yihan , Tao Mingyang , Zhao Jungong
Published: September 2020

Background: Dysfunction of endothelial progenitor cells (EPCs) contributes to vascular disease in diabetes mellitus. However, the molecular mechanism underlying dysfunction of endothelial progenitor cells in diabetes mellitus remains unclear. Our study was aimed to illustrate the potential molecular mechanism underlying diabetic EPCs dysfunction in vivo and vitro. Furthermore, to assess the effect of EPCs transplantation on endothelium regeneration in diabetic rats. Methods: Functional assay in vitro and western blotting was conducted to reveal the association between C-X-C chemokine receptor type 7 (CXCR7) expression and diabetic EPCs dysfunction. To confirm the association between cellular CXCR7 level and EPCs function, the CXCR7 expression of EPCs was upregulated and downregulated via lentiviral transduction and RNA interference respectively. Western blotting was used to reveal the potential molecular mechanism underlying how Stromal-Derived Factor-1(SDF-1)/CXCR7 pathway regulate EPCs function. To elucidate the role of SDF-1/CXCR7 axis in EPCs mediated endothelium regeneration, carotid artery injury model was built in diabetic rats. Then, saline, diabetic, normal or CXCR7 primed EPCs were injected into tail vein after carotid artery injury model was built. Results: Diabetic EPCs dysfunction associated with decreasing CXCR7 expression. Furthermore, EPCs dysfunction can be mimicked by knockdown of CXCR7 in normal EPCs. However, upregulating CXCR7 expression can rescue diabetic EPCs dysfunction. SDF-1/CXCR7 axis positive regulate EPCs cellular function via activating AKT associated Kelch-like ECH-associated protein 1 (keap-1) / nuclear factor erythroid 2‑related factor 2 (Nrf2) axis, which can be reversed by blockage of AKT and Nrf2. CXCR7-EPC transplantation, better than diabetic or normal EPCs, significantly accelerate endothelial repairing and attenuate neointimal hyperplasia in diabetes mellitus. But, the therapeutic effect of CXCR7-EPC transplantation on endothelium regeneration can be reversed by knockdown of Nrf2 molecules. Conclusions: Diabetic EPCs dysfunction associated with decreasing CXCR7 expression. Furthermore, SDF-1/CXCR7 axis positive regulate EPCs cellular function via activating AKT/keap-1/Nrf2 axis. CXCR7 primed EPCs might be used for endothelial regeneration in diabetes associated vascular disease.
Electrospinning Nanofibres of Pullulan Extracted From Phylloplane Fungus, Aureobasidium Pullulans
Authors: Saraf Komal , Vigneshwaran N
Published: September 2020

Aureobasidium pullulans isolated from the phylloplane of Peltophorum tree, produced pullulan, 24 an extracellular polysaccharide. It was grown on three different carbon sources, sucrose, wheat 25 bran and cotton stalk dust, for maximizing the pullulan yield. A. pullulans (67.4 gL-1) had the 26 highest yield followed by A. pullulans MTCC 1991 (63.68 gL-1). Pullulan was characterized by 27 X-ray diffractometer (XRD), Brunauer-Emmett-Teller (BET) surface area analyzer, DSC and NMR. 28 Electrospinning of pullulan blended with poly (vinyl alcohol) (PVA) produced bead-less 29 nanofibres. The optimized parameters for electrospinning were 25 kV applied voltage, 0.5 mL/h 30 flow rate, 18% polymer concentration (pullulan + PVA) and 150 mm tip-to-collector distance. 31 The pullulan nanofibre was characterized by SEM, AFM, BET, contact angle measurement, DSC 32 and CIE color space analyzer. A maximum surface area of 183.4 m2/g while the minimum 33 nanofibre diameter (79 ± 19 nm by SEM) was obtained for the electrospun mat of commercial 34 pullulan + 40% PVA. This work signifies the importance of pullulan extracted from an isolate of 35 Peltopohorum tree for conversion to high surface area nanofibres by electrospinning process.
SATB2 Overexpression Promotes the Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma by Up-Regulating NOX4
Authors: Gao Jie , Meng Ying , Ge Xin , Hou Chen-xing , Zhu Qing-hai , Wang Yi-zhou , Sun Li-fan , Wang Chen-xing , Li Huai-qi , Zhang Tianzhu , Ye Jin-Hai
Published: September 2020

Background: While atypical expression of special AT-rich sequence-binding protein 2 (SATB2) has been approved associated with tumor progression, metastasis and unfavourable prognosis in various carcinomas. However, in oral squamous cell carcinoma (OSCC), both the expressive state and associated functions of SATB2’s are still undefined.Methods: Real-time PCR, western blotting, and immunohistochemistry were used to examine SATB2 expression. In vitro experiments including Flow Cytometry, CCK8 assay, migration assay, wound-healing assay were used to investigate the effects of SATB2 on HN4 cell proliferation, migration and invasion ability. Additionally, an orthotopic implantation assay was performed in nude mice to confirm the effects of SATB2 in vivo. Furthermore, a genome wide siRNA knockdown experiment was performed to explore the potential downstream regulatory mechanism of SATB2 in OSCC.Results: We found that , in clinical samples from a retrospective cohort of 58 OSCC patients, high expression of SATB2 is associated with poor prognosis of OSCC patients. In this study, we investigated SATB2 is highly expressed in OSCC tissues and cell lines ,which can promotes OSCC cells’ proliferation, migration, invasion and tumor growth. Following a genome wide siRNA knockdown experiment, we identified NOX4, a bona fide downstream target of SATB2, which can partially suppress OSCC proliferation. Furthermore, NOX4 knockdown inhibits tumorigenicity, which can be rescued partially by ectopic expression of SATB2.Conclusion: Our findings not only indicate overexpression of SATB2 triggers the proliferative, migratory and invasive mechanisms which are important in the malignant phenotype of OSCC, but also identify NOX4 as the downstream gene for SATB2. These findings indicate that SATB2 may play a key role in OSCC tumorigenicity and may be a future target for the development of new therapeutic regimens.
Prenatal diagnosis of right atrial diverticulum and outcomes: a case report
Authors: Tabnak Peyman , Ghaderi Mohammad
Published: September 2020

Background Right atrial diverticulum is a rare congenital condition which causes the right atrium enlargement. The squeals of this condition can vary from cardiac abnormalities to respiratory distress and systemic thromboembolism, hence Identifying these patients can prevent life-threatening outcomes. Prenatal diagnosis has the benefit of better following up and managing patients to prevent later subsequences. Case presentation Echocardiography of the neonate 3 days after birth showed a massive right atrium with a diverticulum measuring 2.09*2.27 cm connected laterally to the right atrium without any clot in it. A fibromuscular strand was seen at the entry of the diverticulum through the right atrium.CT-Angiography 16 days after birth showed a massive right atrium with a diverticulum in the right hemithorax and confirmed the diagnosis.The patient underwent on low dose aspirin therapy to prevent thromboembolism.After 16 months the patient goes on well this condition without cardiac or respiratory symptoms and echocardiography showed the diverticulum size increased to 3.5*2.5 cm without any clot in it.Surgical resection has not proceeded yet because the patient has been asymptomatic until now.ConclusionBecause of the rarity of this condition, management of these patients is highly dependent on the symptoms they show, and also early diagnosis can prevent further medical squeals. Low doses aspirin is suggested to prevent the formation of thrombosis. Surgical resection can be done in patients with serious cardiac or respiratory abnormality, It is important to do not misdiagnosis this condition with a right atrial aneurysm which involves whole layers of the atrial wall. Although outcomes of both conditions are almost the same, using a proper term to establish an accurate diagnosis preferred.
Fruit Zone Leaf Removal Timing and Extent Alters Bunch Rot, Primary Fruit Composition, and Crop Yield in Georgia-grown ‘Chardonnay’ (Vitis vinifera L.)
Authors: Vogel Annie R. , White Rachael S. , MacAllister Clark , Hickey Cain C.
Published: September 2020

Fruit zone leaf removal is a vineyard management practice used to manage bunch rots, fruit composition, and crop yield. We were interested in evaluating fruit zone leaf removal effects on bunch rot, fruit composition, and crop yield in ‘Chardonnay’ grown in the U.S. state of Georgia. The experiment consisted of seven treatments: no leaf removal (NO); prebloom removal of four or six leaves (PB-4, PB-6), post–fruit set removal of four or six leaves (PFS-4, PFS-6), and prebloom removal of two or three leaves followed by post–fruit set removal of two or three leaves (PB-2/PFS-2, PB-3/PFS-3). Although leaf removal reduced botrytis bunch rot and sour rot compared with NO, effects were inconsistent across the two seasons. Fruit zone leaf removal treatments reduced titratable acidity (TA) and increased soluble solids compared with NO. PB-6 consistently reduced berry number per cluster, cluster weight, and thus crop yield relative to PFS-4. Our results show that post–fruit set fruit zone leaf removal to zero leaf layers aids in rot management, reduces TA, increases soluble solids, and maintains crop yield compared with no leaf removal. We therefore recommend post–fruit set leaf removal to zero leaf layers over no leaf removal if crops characterized by relatively greater soluble solids-to-TA ratio and reduced bunch rot are desirable for winemaking goals.
Honeycomb rare-earth magnets with anisotropic exchange interactions
Authors: Luo Zhu-Xi , Chen Gang
Published: September 2020

We study the rare-earth magnets on a honeycomb lattice, and are particularly interested in the experimental consequences of the highly anisotropic spin interaction due to the spin-orbit entanglement. We perform a high-temperature series expansion using a generic nearest-neighbor Hamiltonian with anisotropic interactions, and obtain the heat capacity, the parallel and perpendicular spin susceptibilities, and the magnetic torque coefficients. We further examine the electron spin resonance linewidth as an important signature of the anisotropic spin interactions. Due to the small interaction energy scale of the rare-earth moments, it is experimentally feasible to realize the strong-field regime. Therefore, we perform the spin-wave analysis and study the possibility of topological magnons when a strong field is applied to the system. The application and relevance to the rare-earth Kitaev materials are discussed.
The Relevance of Self-efficacy, Perception, ICT Ability and Teacher Performance (Study on Islamic Teachers in Semarang, Indonesia)
Authors: Ikhrom Ikhrom
Published: September 2020

The paper aimed to investigate the influence of teacher's self-efficacy and perception on his or her job to performance through ICT ability. The research is a quantitative description using path analysis methods. The population is 1500. They are the Islamic religious teachers in Semarang, Central Java. The researcher used Isaac Michael's table to determine the number of samples. Based on the table, the samples are 290. The Findings are the teachers’ self-efficacy and perception greatly affect to their performance, while perception is also being the critical factor influences teachers to use ICT in the classroom, but self-efficacy is not the vital thing for teachers' ability to use ICT. The finding recommends that self-efficacy and perception of Islamic teachers are vital aspects of the quality of performance. The use of ICT in the classroom is the critical variable for the quality of  teacher performance. AbstrakPenelitian ini bertujuan untuk mengetahui pengaruh self-efficacy dan persepsi guru pada pekerjaannya terhadap kinerja melalui kemampuan TIK. Jenis penelitian ini menggunakan deskriptif kuantitatif dengan metode analisis jalur (path analysis). Populasinya 1500 orang. Mereka adalah para guru Pendidikan Agama Islam di Semarang, Indonesia. Peneliti menggunakan tabel Isaac Michael untuk menentukan jumlah sampel. Berdasarkan tabel tersebut, sampelnya adalah 290. Temuannya adalah self-efficacy dan persepsi guru sangat berpengaruh terhadap kinerja mereka, sedangkan persepsi juga menjadi faktor kritis yang mempengaruhi guru untuk menggunakan TIK di kelas, tetapi self-efficacy bukan hal yang vital bagi kemampuan guru menggunakan TIK. Temuan ini merekomendasikan bahwa self-efficacy dan persepsi guru Islam merupakan aspek penting dari kualitas kinerja. Penggunaan TIK di kelas merupakan variabel penting untuk kualitas kinerja guru.
The Peaceful Teaching Method of Datok Sulaiman in Spreading Islam in Tana Luwu, Indonesia.
Authors: Bulu Bulu , Nuryani Nuryani , Karim Abdul Rahim
Published: September 2020

This study discusses the teaching method of Datok Sulaiman in spreading Islam in Tana Luwu, South Sulawesi, Indonesia. This study employed historical and sociological approaches to unpack those research aims. The research findings show that the teachings of Islam transmitted throughout the Tana Luwu region used a peaceful approach without involving any violence with the support of Datok Luwu. Datok Sulaiman mostly used dialogue, Sufistic, and supernatural approaches to spread Islam. Therefore, he could successfully spread Islam in Tana Luwu, including the conversion of XV King Luwu in 1603 which influenced the rapid conversion of Islam in the area.AbstrakStudi ini membahas metode pembelajaran Datok Sulaiman dalam menyebarkan Islam di Tana Luwu. Sulawesi Selatan, Indonesia. Pendekatan yang digunakan adalah pendekatan historis dan sosiologis. Analisis yang digunakan adalah reduksi data, penyajian data, dan penarikan kesimpulan. Hassil penelitian menunjukkan bahwa ajaran Islam berkembang pesat di seluruh wilayah Tana Luwu secara damai tanpa kekerasan berkat peran Datok Sulaiman. Metode pengajaran Islam damai yang digunakan oleh Datok Sulaiman adalah dialog, pembelajran sufisme, dan supranatural. Hal ini berdampak pada adanya dukungan Raja Luwu XV pada 1603 M, sehingga agama Islam berkembang dengan cepat
Research on Finite Element Simulation and Parameters Optimization of
Milling 7050-T7451 Aluminum Alloy Thin-walled Parts
Authors: Yang Song , Yin Tie , Wang Feiyue
Published: September 2020

Background:

Thin-walled parts of aluminum alloy are easy to occur machining deformation duo to the
characteristics of thin wall, low rigidity, and complex structure.

Objective:

To reduce and control the machining deformation, it is necessary to select reasonable machining parameters.

Method:

The influence of milling parameters on the milling forces, milling temperature, and machining deformation was
analyzed through the established model based on ABAQUS. Then, the corresponding empirical formula was obtained by
MATLAB, and parameters optimization was carried out as well. Besides, a lot of patents on machining thin-walled parts
were studied.

Results:

The results shown that the prediction error of milling forces is about 15%, and 20% of milling temperature. In
this case, the optimized milling parameters are as follows: ap=1 mm, ae=0.1 mm, n=12 000 r/min, and f=400 mm/min. It is
of great significance to reduce the machining deformation and improve the machining quality of thin-walled parts.
Toxicity Risks of Nanomaterials Used in the Building Construction Materials
Authors: Singh Nakshatra Bahadur , Bilal Muhammad , Kırgız Mehmet Serkan , Nguyen Tuan Anh , Susai Rajendran , Sheikholeslami Mohsen , Abohamzeh Elham
Published: September 2020

Introduction:

In recent years, there has been a growing research interest on the applications
of a range of nanostructured materials in construction industry (i.e., asphalt concrete, bricks,
concrete, timber, steel, and mortar), manufacturing, electronics, cosmetics, and medicine. The use
of nanoscale structures in the construction industry offers exceptional physicochemical characteristics
for the modification of construction materials. Nanomaterials, which are being used in cement
and concretes, are carbon nanomaterials (Graphene, CNTs, CNFs), nanosilica, nano Al2O3, nanometakaoline,
nano CaCO3, nano Fe2O3 and nanoTiO2.

Methods:

These materials improve the properties of concretes by modifying the microstructure and
also improve the mechanical properties. The improvement in mechanical and durability properties
of concretes in the presence of nanoparticles is due to their smaller size (<100 nm), high surface area,
and energy.

Results:

Nevertheless, all these nanoscale particles find their way (either directly or indirectly) to
various environmental matrices, such as groundwater, surface water, rivers, seas, lakes, and soil.
The potential bioaccumulation of metal oxide nanostructures results in undesirable effects on animals,
aquatic biota, plants, and humans. Therefore, it has become crucial to determine toxicity levels
during the use of these multifunctional nanoscale materials.

Conclusion:

This study presents an overview of the advantages and disadvantages of nanomaterials
in concretes and related materials. A particular emphasis has been given to discuss the potential
toxicity risks of nanomaterials used in building construction materials.
АКТУАЛЬНЫЕ ВОПРОСЫ УНИФИКАЦИИ ПРАВОВОЙ ЗАЩИТЫ ИНТЕРЕСОВ ГОСУДАРСТВ – ЧЛЕНОВ ЕАЭС В СФЕРЕ ВНЕШНЕТОРГОВОЙ ДЕЯТЕЛЬНОСТИ
Authors: Denisevich A.V.
Published: September 2020

Статья посвящена вопросам унификации норм права в сфере защиты внешнеторговых интересов. Автором проведен сравнительно-правовой анализ способов и инструментов таможенно-тарифного и нетарифного регулирования, применяющихся в законодательстве государств – участников ЕАЭС и ЕАЭС в целом. Выдвигается тезис о недостаточном уровне унификации законодательства в обозначенной сфере. Также рассматриваются вопросы формирования универсального понятийного аппарата и инструментария, используемого в национальном законодательстве стран – членов ЕАЭС. Анализируются понятие и признаки внешнеторговой деятельности, определяется правовой статус таможенной пошлины, раскрываются особенности дефиниций «тарифные преференции», «тарифные льготы», «тарифные квоты», «особые пошлины» и др.
DA LI JE VOJISLAV KOŠTUNICA ZAISTA POBEDIO U PRVOM KRUGU GLASANjA NA IZBORIMA 2000. GODINE?
Authors: Radonjic Zoran
Published: September 2020

U radu se na osnovu analize i upoređivanja javno dostupnih podataka pokušava dati odgovor na pitanje da li je predsednički kandidat Demokratske opozicije Srbije Vojislav Koštunica zaista ostvario izbornu pobedu u prvom krugu glasanja na izborima za predsednika Savezne Republike Jugoslavije 2000. godine. Najpre je dato poređenje zvaničnih izbornih rezultata sa izbornim rezultatima koje su objavljivali stranački štabovi i došlo se do zaključka da se oni međusobno ne slažu samo kod zbirnog broja glasova za predsedničke kandidate, dok su gotovo potpuno istovetni kada se radi o rezultatima koji su objavljivani za nivoe opština i gradova. U drugom delu teksta navedene su i analizirane evidentne nepravilnosti i nedostaci zvanično objavljenih rezultata i to one pravne prirode (kod utvrđivanja rezultata glasanja nisu uzeti u obzir glasovi sa teritorije AP Kosovo i Metohija, jer su rezultati sa biračkih mesta poništeni, a ponovljeni izbori nisu bili sprovedeni, iako je to bila zakonska obaveza) i materijalno-logičke prirode (očigledna prekrajanja rezultata glasanja vojnika na odsluženju vojnog roka i dela albanskog biračkog tela u opštinama Preševo i Bujanovac u korist predsedničkog kandidata Slobodana Miloševića i zamena glasova između predsedničkih kandidata na pojedinim biračkim mestima). U završnom delu teksta, analiziran je ukupni obim i efekat opisanih nepravilnosti na izborni rezultat i došlo se do zaključka da su zvanični izborni rezultati najvećim svojim delom realni i tačni, te da se njihov ishod, izbor Vojislava Koštunice za predsednika SRJ u prvom izbornom krugu, može smatrati i legalnim sa pravnog aspekta i legitimnim izrazom volje biračkog tela.
¿Puede hablar el subalterno?
Authors: Spivak Gayatri Chakravorty
Published: September 2020

Este artículo fue publicado originalmente en Cary Nelson y Larry Grossberg (eds.). Marxism and the interpretation of Culture. University of Illinois Press. Chicago. 1988. Además, en el libro, A critique of poscolonial reason. Toward a history of vanishing present. Harvard University Press. Cambridge. Existe otra traducción al castellano publicada en Orbis Tertius. VI. 1998: 175-235 (Argentina). Traducción del inglés de Antonio Díaz G., estudiante de antropología de la Universidad Nacional de Colombia. Revisada por Santiago Giraldo y María Teresa Salcedo, investigadores del ICANH.
The Politics of Ethnicity: Indigenous Peoples in Latin American States, David Maybury-Lewis (ed.)
Authors: Oslender Ulrich
Published: September 2020

Reseña escrita por Ulrich Oslender
Aplilkasi Teknologi Budidaya dan Diversifikasi Olahan Buah Nangka Unggul Kota Palu
Authors: Adelina Enny , Tiwow Vanny M.A.
Published: September 2020

Nangka lokal Palu merupakan salah satu buah unggulan yang memiliki keistimewaan rasa legit dan tekstur yang renyah serta menjadi buah tangan wisatawan yang berkunjung ke Palu, namun teknologi budidaya yang dilakukan petani umumnya sangat sederhana terbukti dari pertanaman nangka dilakukan sebatas tanaman pengisi pekarangan dan sebagai tanaman penghijauan di sepanjang jalur trans Kabupaten Sigi ke kota Palu tanpa pemeliharaan yang memadai, demikian halnya pemanfaatan dan pengolahan buah nangka yang dipanen sepanjang tahun umumnya dijual dalam bentuk buah segar dengan harga yang cenderung fluktuatif, sehingga petani belum menikmati manfaat ekonomisnya, karenanya dibutuhkan perbaikan teknik budidaya nangka dan  pengelolaan pasca panen nangka berupa pengolahan buah nangka menjadi berbagai produk olahan yang bernilai ekonomi tinggi sehingga akan berdampak terhadap peningkatan pendapatan petani. Pelaksanaan program pengabdian kepada masyarakat dalam Program Ipteks bagi Masyarakat dilakukan dalam bentuk penyuluhan dan pelatihan kepada dua kelompok Tani Wanita di Kabupaten Sigi yaitu Kelompok Tani Harapan Desa Tulo dan Kelompok Tani Selaras Desa Kabobona bekerjasama dengan UKM Tiara yang bergerak dalam usaha pembuatan keripik nangka. Luaran yang ingin dicapai yaitu terjadinya perbaikan teknologi budidaya nangka serta pengolahan buah nangka menjadi kripik nangka dan dodol nangka. Hasil kegiatan ini menunjukkan bahwa teknologi budidaya nangka dan pengolahan buah nangka yang telah diperkenalkan melalui penyuluhan dan pelatihan kepada khalayak sasaran telah mengubah laku khalayak, dibuktikan melalui penanaman benih nangka bermutu, mengaplikasikan pupuk organik yang berasal dari limbah dapur dan trampil membuat kripik dan dodol nangka disertai tumbuhnya minat dalam menerapkan teknologi budidaya dan pengolahan buah nangka untuk usaha industri rumah tangga.
Medicaid Expansion and Utilization of Antihyperglycemic Therapies
Authors: Sumarsono Andrew , Buckley Leo F. , Machado Sara R. , Wadhera Rishi K. , Warraich Haider J. , Desai Rishi J. , Everett Brendan M. , McGuire Darren K. , Fonarow Gregg C. , Butler Javed , Pandey Ambarish , Vaduganathan Muthiah
Published: September 2020

Objective: Certain antihyperglycemic therapies modify cardiovascular and kidney
outcomes among persons with type 2 diabetes
mellitus (T2DM), but uptake in practice appears restricted to certain
demographics. We examine the association of Medicaid expansion with use of and
expenditures related to antihyperglycemic therapies among Medicaid
beneficiaries.

Methods: We employed a difference-in-difference design to analyze the
association of Medicaid expansion on prescription of non-insulin
antihyperglycemic therapies. We used 2012-2017 National & State Medicaid data
to compare prescription claims and costs between states that did (n=25) and did
not expand (n=26) Medicaid by January 2014.

Results: Following Medicaid expansion in 2014, average non-insulin
antihyperglycemic therapies per state/1,000 enrollees increased by 4.2%/quarter
in expansion states and 1.6%/quarter in non-expansion states. For SGLT2i and
GLP-1RA, quarterly growth rates per-1,000 enrollees were 125.3% and 20.7% for
expansion states and 87.6% and 16.0% for non-expansion states, respectively. Expansion states had faster utilization and total spending growth in SGLT2i
and GLP-1RA than non-expansion
states. Difference-in-difference estimates for
change in volume of prescriptions after Medicaid expansion between expansion
vs. non-expansion states was 1.68 (1.09 to 2.26;P<0.001) for all non-insulin
therapies, 0.125 (-0.003 to 0.25;P=0.056) for SGLT2i, and 0.12 (0.055 to
0.18;P<0.001) for GLP-1RA.

Conclusion: Use of non-insulin
antihyperglycemic therapies, including SGLT2i
and GLP-1RA, increased among low-income adults in both Medicaid expansion and
non-expansion states, with a significantly greater increase in overall use and
in GLP-1RA use in expansion states. Future evaluation of the population-level
health impact of expanded access to these therapies is needed.
Comparative Effectiveness of SGLT2 Inhibitors, GLP1 Receptor Agonists, DPP4 Inhibitors, and Sulfonylureas on Risk of Kidney Outcomes: emulation of a target trial using healthcare databases
Authors: Xie Yan , Bowe Benjamin , Gibson Andrew K. , McGill Janet B. , Maddukuri Geetha , Yan Yan , Al-Aly Ziyad
Published: September 2020

Objective: To examine the
comparative effectiveness of SGLT2i, GLP1, DPP4, and sulfonylureas on risk of
kidney outcomes among people with type 2 diabetes.

Research Design and Methods: US Veterans initiated on SGLT2i (n=18,544), GLP1 (n=23,711), DPP4
(n=39,399), or sulfonylureas (n=134,904) were followed for up to 3 years to
evaluate the risk of the composite outcome of estimated glomerular filtration
rate (eGFR) decline >50%, end stage kidney disease (ESKD), or all-cause
mortality. Risks were estimated using survival models adjusted for pre-defined
covariates as well as covariates identified by a high-dimensional variable
selection algorithm through application of generalized propensity scores.

Results: Compared
to those treated with sulfonylureas, treatment with SGLT2i, GLP1, and DPP4 was
associated with lower risk of the composite outcome (HR=0.68 (0.63,0.74), HR=0.72
(0.67,0.77), and HR=0.90 (0.86,0.95), respectively). While we
did not observe statistically significant difference in risk between the SGLT2i
and GLP1 arms (HR=0.95 (0.87,1.04)), both SGLT2i and GLP1 had lower risk of the
composite outcome than DPP4 (HR=0.76 (0.70,0.82) and HR=0.79 (0.74,0.85),
respectively). Analyses by eGFR category suggested that compared to the
sulfonylureas arm, those in the SGLT2i and GLP1 arms exhibited lower risk of
the composite outcome in all eGFR categories including eGFR <45 ml/min/1.73
m2. Compared to DPP4, both SGLT2i and GLP1 exhibited reduced risk of
the composite outcome in eGFR <90 to ≥60, <60 to
≥45, and <45 ml/min/1.73 m2.

Conclusions: In diabetes
mellitus type 2, treatment with SGLT2i or GLP1 compared to DPP4 or
sulfonylureas was associated with lower risk of adverse kidney outcomes.
Práticas pedagógicas para o desenvolvimento do letramento empreendedor
Authors: Silva Valdemir José Máximo Omena da , Martins Silvana Neumann , Forneck Kári Lúcia , Vizzotto Patrick Alves , Omena Sarah Patrícia Aguiar e Silva
Published: September 2020

Apresentam-se os resultados quantitativos de uma pesquisa de tese que teve como foco o ensino do empreendedorismo mediado por metodologias de Abordagem Colaborativa. Por meio de uma pesquisa-ação, ministrou-se, durante um semestre, tópicos de empreendedorismo em uma turma de 44 alunos da graduação de uma universidade comunitária do Rio Grande do Sul. No primeiro e último dia de aula, os alunos responderam a um questionário denominado de Instrumento de Medida do Conhecimento Empreendedor Básico (IMCEB) a fim de aferir aspectos do saber empreendedor de cada um. Ao término do semestre, comparou-se a média de desempenho do grupo na primeira e segunda aplicação do IMCEB, mediante testes de estatística, a fim de verificar se a diferença observada poderia ser considerada significativa. Evidenciou-se um aumento significativo na média de acertos, e assim, discute-se que uma das hipóteses para explicação desse acontecimento, deriva das práticas de ensino adotadas na disciplina.
Tecnologias educativas e plataformas digitais na gestão educacional
Authors: Fernandes Preciosa , Figueiredo Carla
Published: September 2020

A integração de plataformas digitais (PD) no sistema escolar português visou otimizar os processos de ensino aprendizagem, de gestão e administração educacional e de comunicação entre profissionais. No quadro desta problemática esta investigação apresenta uma leitura sobre a utilização de PD na gestão educacional dos agrupamentos de escolas, em Portugal, construída através da análise dissertações de mestrado e teses de doutoramento desenvolvidas sobre esta temática. Os resultados revelam que os temas mais investigados se relacionam com a relação entre as PD e a comunicação e gestão de informação e a relação escola-família. Identificam-se ainda como contributos das PD a melhoria dos processos comunicacionais, da relação escola-família e da agilização de processos e como constrangimentos a falta de condições e de suporte técnico aos professores, bem como falta formação especifica. São apontadas algumas sugestões relacionadas com o reforço e atualização de equipamentos e a promoção de ações de capacitação.
Un consenso inestable: la cuestión de la neutralidad en la prensa y la opinión pública de Buenos Aires durante los inicios de la Gran Guerra
Authors: Sánchez Emiliano Gastón
Published: September 2020

El presente artículo analiza el lugar ocupado por la cuestión de la neutralidad en la prensa y la opinión pública de Buenos Aires durante los inicios de la Gran Guerra. La campaña en defensa de la neutralidad estatal permite advertir las presiones ejercidas sobre el llamado “consenso neutralista”, y las complicaciones que debió enfrentar el gobierno argentino para mantener esa posición ante la contienda. A su vez, el análisis de esta problemática, a la luz de un vasto conjunto de publicaciones periódicas, permite detectar la existencia de ciertos “usos” de la neutralidad por parte de algunos sectores de la prensa que, amparados en una supuesta defensa de los neutrales, encubrían reclamos muy sesgados contra las potencias europeas (en particular, contra Alemania) pero también como un ariete para las críticas al gobierno conservador de Victorino de la Plaza.
El disenso y la polémica en el espacio público
Authors: Bracco Olga Natividad
Published: September 2020

Revisión del libro El análisis del discurso polémico. Disputas, querellas y controversias por Ana Soledad Montero (Comp)
Literaturas y disidencias sexuales: sub-versiones, disturbios, genealogías
Authors: Saxe Facundo
Published: September 2020

Este texto realiza una aproximación inicial a la idea de literaturas y disidencias sexuales como posibilidad crítica contra-hegemónica del campo cultural argentino. A partir de una serie de referencias situadas a la idea de disidencias sexuales, se realiza un recorrido general sobre algunas apariciones textuales críticas y teóricas (relacionadas con las subversiones sexo-genéricas) en campos disciplinares como los estudios literarios, la crítica literaria y los estudios comparados, entre otros. Asimismo, este recorrido marca algunas etapas posibles, así como diferentes conceptualizaciones de las disidencias sexuales en la construcción de conocimiento en relación con la investigación científica sobre literaturas, focalizando en las posibilidades subversivas de determinadas emergencias en el campo cultural. Para esto, se construyen series de hitos textuales vinculados a la investigación y las apariciones críticas disciplinares en diferentes momentos de las últimas décadas. El análisis focaliza en apariciones puntuales que ocurren en Argentina, sin pretender exhaustividad ni completitud, ya que la idea principal es una intervención introductoria, básica y general a la cuestión.
Un fulgor de estrellas. La configuración de una memoria abyecta en Vivir con virus y Aparecida de Marta Dillon
Authors: Rubino Atilio R. , Sánchez Silvina
Published: September 2020

En este artículo abordamos el análisis de dos libros de Marta Dillon, Vivir con virus (publicado en 2004 y que compila las columnas que escribió para Página/12 desde 1995 hasta 2003) y Aparecida (2015). Se propone que la poética de Dillon construye una memoria abyecta, por un lado, porque se narra la experiencia de la enfermedad trazando relaciones entre la memoria de la última dictadura y los sueños de exterminio (Giorgi), es decir, la utilización biopolítica del virus del VIH-SIDA. Y, por otro lado, porque explora los cruces entre memorias del pasado reciente y disidencia de sexo-género, de modo tal que excede los tópicos discursivos de la segunda generación de HIJOS, y configura una memoria anómala que se compone como una política de lo íntimo, una pedagogía de la maternidad y una celebración del contacto de los cuerpos.
La belleza del diablo: Moda, mujer y espacio publico en Tucumán (1900-1923)
Authors: Crusco Eugenia
Published: September 2020

Este artículo explora las representaciones que sobre la figura de las mujeres y su relación con la moda hiciera la prensa y otros registros escritos que circularon en Tucumán durante las primeras décadas del siglo XX, periodo caracterizado por su desarrollo económico y modernización de la ciudad. Consideramos que la prensa local se convirtió en un medio ideal para hacer inteligibles las ideas y valores proyectados sobre la estética y los cuerpos de las mujeres. Analizaremos las representaciones que se difundieron en la prensa sobre la mujer, su vestir y su comportamiento. Nos interesan especialmente aquellos casos en donde la indumentaria se convirtió en un vehículo de transgresiones por actuar de forma disruptiva frente al orden genérico imperante.
Apuntes sobre ciertas resistencias en el lenguaje: el género del español
Authors: Scotto Victoria
Published: September 2020

En este trabajo se abordará una cuestión central en la investigación lingüística contemporánea: la del lenguaje no sexista o “lenguaje inclusivo” y la intervención política de la Real Academia Española en esta cuestión. El objetivo de este trabajo es dar cuenta de una discusión centrada en la posibilidad de ejercer transformaciones en la lengua española con miras a cambiar algunas de las desigualdades estructurales que la integran. La metodología y teoría desde la cual se aborda el objeto es la glotopolítica: un modo de abordaje del estudio de la lengua que pone en foco el carácter político que constituye toda discusión sobre el lenguaje.
Conversación con Cintia Pili: núcleos y logros de la lucha travesti-trans desde las organizaciones sociales
Authors: Muro María , Palermo Gimena
Published: September 2020

Conversación con Cintia Pili: núcleos y logros de la lucha travesti-trans desde las organizaciones sociales
Шедевры учебной литературы по японскому языку как иностранному (2): Комикс «Мальчуган» (по одноимённой повести Нацумэ Сосэки)
Authors: ДЫБОВСКИЙ Александр Сергеевич
Published: September 2020

В статье даётся краткий обзор учебной литературы по японскому языку, составленной в виде комиксов, а также описываются основные параметры учебника, построенного на материале повести выдающегося японского писателя Нацумэ Сосэки «Мальчуган», а именно: его структура, содержание, приложения, особенности введения лексики, иероглифики и грамматики, система упражнений и связанные с учебником интернет-ресурсы. Описываемый учебник представляет уникальный материал для преподавания японского языка на среднем и продвинутом уровнях, он вводит обучаемых в историю японской культуры, стимулирует интерес к изучению японской литературы.

преподавание японского языка,
шедевры учебной литературы,
жанр комикса в преподавании иностранного языка,
комикс «Мальчуган»

This publication is dedicated to the Japanese language textbook for foreigners published in Tokyo in 2011 and based on the story of the outstanding Japanese writer Soseki Natsume “Botchan”, which is presented in the textbook in the form of a comic strip. The article gives a brief overview of the Japanese language textbooks compiled in the form of comics. The author describes the main parameters of the above-mentioned textbook, its structure, content and applications, as well as vocabulary, hieroglyphics and grammar, the exercise system, and the Internet-related textbook resources. The creation of an educational comic strip on the basis of an outstanding work of Japanese literature seems to us extremely fruitful, since the educational process is enriched with aesthetic elements. Drawings provide important keys for understanding the text, and the content of a literary masterpiece gives us rich topics for various types of communication in the classroom. The described textbook contains wonderful material for teaching Japanese at intermediate and advanced levels. It introduces students to the history of Japanese culture and stimulates interest in the study of Japanese literature.

teaching Japanese language,
masterpieces of educational literature,
comic book genre in teaching a foreign language,
comic book “Botchan”
Внешняя политика США в восприятии и оценках современного американского общества
Authors: ГАРУСОВА Лариса
Published: September 2020

Анализируется взаимосвязь и корреляция современной внешнеполитической стратегии США с общественной рефлексией на неё. Информационной основой работы являются результаты социологических опросов ведущих американских исследовательских центров, статистические данные, статьи, официальные документы. Прослежена связь официальных внешнеполитических доктрин и мнения американских граждан в отношении России и Китая. Выявлена корреляция между усилением антикитайских настроений в США за последние два года и появлением новой официальной стратегии Вашингтона в отношении КНР («Стратегический подход США к КНР») от 20 мая 2020 г.

внешняя политика,
США,
стратегия,
рефлексия,
общественное мнение,
Россия,
Китай,
национальная безопасность

This article analyzes the relationship and correlation of the US modern foreign policy strategy with public reflection on it. Washington's active foreign policy and US claims to the role of world leader are supported by American society in recent decades. The informational basis of this work is the analysis of the sociological surveys of leading American research centers, statistics, academic articles, as well as official documents on the studied issues. The study revealed the peculiarities of the perception of traditional and new threats to national and international security by the American elite and society. The author traces the connection between official foreign policy doctrines and the opinions of American citizens regarding Russia and China. A correlation was found between the strengthening of anti-Chinese sentiment in the US over the past two years and the appearance of a new official strategy of Washington towards the PRC (“United States Strategic Approach to The People’s Republic of China”) in May 20, 2020.

foreign policy,
USA,
strategy,
reflection,
public opinion,
Russia,
China,
national security