bluuebunny/crossref_metadata_2025 huggingface dataset:
Global Paediatric Hepatitis Outbreak
Authors: Shakil Saad , Akhtar Sareema Eman
Published: November 2022

Madam,
WHO is investigating a global outbreak of severe acute hepatitis of questionable aetiology among children. Since this is not linked to Hepatitis types A-E, there are still ongoing investigations to explore the causative agent for this worldwide outbreak. At least 228 cases of acute hepatitis of unknown origin had been recorded from 20 countries since May 1, 2022, in Europe, America and other countries, with the highest number of cases recorded in the United Kingdom, 145 since January (1). Adenovirus was found in 74 individuals, suggesting that there may be a possible association. However, this hypothesis needs further investigation. The United Kingdom has recently witnessed an increase in adenovirus infections; however, this might be due to increased testing rather than this epidemic. (2) As a result, affected countries have increased their surveillance efforts and are receiving additional support from WHO.
Although the cases ranged in age from one month to sixteen years, the majority of the children who were affected were under the age of five and had gastrointestinal symptoms such as abdominal pain, nausea, and diarrhoea, as well as jaundice and elevated liver enzymes (AST and ALT greater than 500 IU/L). Infectious hepatitis (Types A, B, C, D, E), is the most common cause of hepatitis, was not found. Around 10% of these children have needed a liver transplant, and at least one has died. WHO's working probable case definition has been an individual presenting with acute hepatitis (non-hepatitis A-E) with serum transaminase >500 IU/L (AST or ALT), who is 16 years or younger, since 1 October 2021 (1,2). Hepatitis is a liver inflammation caused by viral infections, primarily the Hepatitis A, B, and C viruses, as well as a variety of other factors such as alcohol consumption, drugs, medicines, and other medical disorders. Fever, exhaustion, lack of appetite, nausea, vomiting, stomach discomfort, dark urine, light-coloured stools, joint pain, and jaundice are all signs and symptoms of hepatitis. The underlying cause determines the hepatitis treatment. (3). Parents and doctors are advised to look out for these signs and symptoms. Adenovirus, a double-stranded DNA virus distributed by close contact, respiratory droplets, and fomites, is most commonly associated with respiratory illness.
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Medidas de Dispersión
Authors: Flores Ccanto Florencio , Gálvez Morales Lourdes , Lau Mego César , Villegas Lira Marianella Marilú , Dávila Huamán Vicente Carlos , Menacho Vargas Isabel
Published: November 2022

El familiarizar de las prácticas matemáticas sobre la enseñanza de la estadística básica, que aborda contenidos de medidas de dispersión, varianza, desviación estándar, coeficiente de variación y coeficiente de asimetría, apoyándose con el emulador Casio fx-570LA-X Classwiz en el proceso de enseñanza-aprendizaje del estudiante interesado en aprender los temas antes mencionados. Una de las bondades del emulador es que hace muy didáctico abordar cada tema haciéndola más sencilla, amena, divertida y les crea mucho interés con los temas de estadística. Los ejemplos y ejercicios desarrollados en el presente trabajo son situaciones de la vida real y casos motivadores. El libro termina presentando ejercicios adicionales para que el estudiante los pueda abordar en sus tiempos libres.
Medidas de Tendencia Central
Authors: Gálvez Morales Lourdes , Lau Mego Cesar , Chirinos Maldonado Daniel Marcos , Flores Ccanto Florencio , Menacho Vargas Isabel , Dávila Huamán Vicente Carlos
Published: November 2022

En el proceso de enseñanza-aprendizaje de la Estadística Básica, en primer lugar, se parte del estudio de la Media aritmética, apoyándose con el emulador Casio fx-570LA-X Classwiz, algunos autores presentan el tema otras herramientas estadísticas, como el SPSS, Minitab, etc. En el presente libro desarrollamos los contenidos de Media, Mediana y Moda utilizando en todo momento el emulador Casio fx-570LA-X Classwiz, que les hace muy didáctico abordar cada tema, haciéndola más sencilla, amena, divertida y les crea mucho interés en los temas de estadística que lo abordan en el sílabo de la asignatura. Los contenidos presentados se les hace muy familiar. Los ejemplos y ejercicios desarrollados en clase son situaciones de la vida real y casos motivadores. El libro culmina presentando como ejercicio algunas situaciones de la vida cotidiana.
THE URGENCY OF TEXTUAL CRITICISM OF THE NEW TESTAMENT INERRANCY
Authors: Wariki Valentino , Gernaida Krisna R. Pakpahan
Published: November 2022

Textual criticism has long existed as part of the hermeneutic discipline. However, many communities reject this approach. Even scientifically, textual criticism provides a new understanding of the scriptures, especially the New Testament. The many variants of the Greek New Testament make textual criticism present to reconstruct the original text of the Greek New Testament. Nevertheless, on the other hand, this scientific development deals with the doctrine of the inerrancy of the Bible. This study attempts to present the logical foundations of the urgency of textual criticism related to the doctrine of the inerrancy of the Bible. This study examines the importance of textual criticism of the inerrancy of the Bible. The approach used is exploratory qualitative. The results showed that the hermeneutic method of textual criticism did not weaken the truth of the Bible. The inerrancy of the Bible is maintained when an interpreter uses this method. The meaning of the text is more understandable and far from error because of the approach to the highlighted New Testament Greek.
REACTIVE AND COMPENSATORY CHANGES IN PITUITARY-THYROID AXIS INDUCED BY REDUCED INTAKE OF DEUTERIUM
Authors:   A.P. Avtsyn Research Institute of Human Morphology of FSBSI «Petrovsky NRCS», Timokhina E. P. , Obernikhin S. S. ,   A.P. Avtsyn Research Institute of Human Morphology of FSBSI «Petrovsky NRCS», Yaglova N. V. ,   A.P. Avtsyn Research Institute of Human Morphology of FSBSI «Petrovsky NRCS»
Published: November 2022

The paper represents the results of the investigation aimed at elucidation of reactive and com-pensatory changes in pituitary-thyroid axis induced by reduced intake of deuterium, which indicate that both types of changes were developed in peripheral part of the axis.
PECULIARITIES OF DISTRIBUTION OF Y-CHROMOSOME HAPLOGROUPS IN GENERATIONS OF MEGAPOLIS POPULATION UNDER ACTION OF MIGRATION
Authors:   N.I. Vavilov Institute of General Genetics Russian Academy of Sciences, Udina I.G. , Gracheva A.S. ,   N.I. Vavilov Institute of General Genetics Russian Academy of Sciences,   V. A. Negovsky Research Institute of General Reanimatology, Vasiliev Yu.А. ,   Department of Children's Stomatology, Orthodontic and Orofacial Surgery Kuban' State Medical University, Pobedonosteva E.Yu ,   N.I. Vavilov Institute of General Genetics Russian Academy of Sciences, Kurbatova O.L. ,   N.I. Vavilov Institute of General Genetics Russian Academy of Sciences
Published: November 2022

In three generations, peculiarities of changes in the profile of Y-chromosome haplotypes were studied. Genetic demographic questionnaire collecting and genotyping by 18 STR of Y-chro-mosome were performed, haplogroups of Y-chromosome were detected. In generations of megalopolis population, specific peculiarities of the frequency profiles of Y-chromosome hap-logroups were detected, due to migration of population to megapolis. In the youngest genera-tion, in comparison with two previous generations statistically significant accumulation in the gene pool of megalopolis population “southern” by origin haplogroups bringing to megapolis with migrant flows. Obtained results are in good agreement with ethnic contents of migrants to Moscow detected by questionnaire data.
PROBLEMS OF SPACE BIOLOGY AND GENETICS
Authors:   M.V. Lomonosov Moscow State University, Aslanyan M.M.
Published: November 2022

The article discusses the main problems and stages of the development of space biology, med-icine and genetics. Biological tests on different species of animals and plants, in the conditions of space flight, allowed scientists to predict the safety of human flight into space. The existence of a negative influence of space factors on biological processes and morphophysiological structure of organisms requires further research to ensure the biological safety of a long-term human stay in space.
PATHOPHYSIOLOGICAL FACTORS OF PREMATURE HUMAN AGING
Authors:   FGBNU«NIIOPP», IPPI RAN, Cherkasov D. , Petrova E. N. ,   FGBNU«NIIOPP», IPPI RAN
Published: November 2022

The article discusses methods for increasing human life expectancy.Using MRI, the condition of the muscular corset of the spine was diagnosed with localization of dystrophic manifesta-tions in the vertebrae and intervertebral discs. Osteochondrosis of the spine is considered as premature aging of bone and cartilage tissues caused by spastic conditions in the interverte-bral muscles.
COMPARATIVE CHARACTERISTICS OF KIDNEY WOUND HEMOSTASIS WHEN USING PECTINS IN AN EXPERIMENT
Authors:   Kuban Medical Institute, Berdysh D. S. , Pavlenko S.G. ,   Kuban Medical Institute, Marchenko Evgeny ,   Kuban State Agrarian University
Published: November 2022

The article presents data on the hemostatic properties of apple and citrus pectins on the model of an incised wound of the lower pole of the kidney (parenchymal bleeding). The time of com-plete hemostasis when using pectins is 10 seconds. The volume of blood loss does not exceed 0.3 mg per organ.
SYNTHESIS AND INTRACELLULAR TRAFFIC OF β-CATENIN DURING GROWTH OF THE ADRENAL COTREX
Authors:   FSBSI “Petrovsky NRCS", Yaglov V.V. , Nazimova S.V. ,   FSBSI “Petrovsky NRCS”, Tsomartova E.S. ,   FSBSI “Petrovsky NRCS”,   Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Lomanovskaya T. A. ,   Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Published: November 2022

The article presents data on the similarity of synthesis and traffic of β-catenin in the cells of zona glomerulosa, fasciculata and reticularis of the rat adrenal cortex during growth of the organ. After termination of the growth, the intracellular traffic of β-catenin into the nucleus was maintained due to a decrease in the incorporation of β-catenin into the outer cytoplasmic membranes, which indicates a decrease in its synthesis.
NONINVASIVE DIAGNOSTIC METHODS FOR CHRONIC PERIODONTITIS BASED ON ORAL FLUID BIOMARKER ASSESSMENT: A REVIEW
Authors:   Kuban State Medical University, Gayvoronskaya T.V. , Zub A.A. ,   Kuban State Medical University, Ayupova F.S. ,   Kuban State Medical University
Published: November 2022

Methods of quantitative determination of biomarkers in oral fluid allow to reveal early signs of chronic periodontitis development. It is of interest to further improve the known methods for more affordable and effective application in periodontal clinical practice.
ECOLOGICAL AND BIOCHEMICAL ADAPTATIONS OF LIPIDS AND FATTY ACIDS CERTAIN FISH SPECIES FROM THE IRMINGER SEA TO DEEPWATER HABBIT
Authors:   Institute of Biology of the Karelian research Centre of the Russian Academy of Sciences, Murzina S. A. , Voronin V. P. ,   Institute of Biology of the Karelian research Centre of the Russian Academy of Sciences, Artemenkov D. V. ,   Russian Federal Research Institute Of Fisheries and Oceanography, Orlov A. M. ,   P.P. Shirshov Institute of Oceanology of the Russian Academy of Sciences
Published: November 2022

Lipid profiling and identification of lipid status were carried out in certain species of meso-pelagic fish species - Lampanyctus macdonaldi and Bathylagus euryops of the Irminger Sea, which are manifested as integral components of the aquatic ecosystem and prevail in habitat, life cycle, specific development, intraspecific degree and the presence of specialization. For the first time, changes in the lipid profiles and the contents, observed by the specific adaptive sensitivity of fish to a deep-sea lifestyle, have been revealed.
EFFECT OF HEMOGLOBIN AND SOLVENTS ON THE DECOMPOSITION OF N-ETHYLTHIOUREA NITROSYL IRON COMPLEX
Authors:   Institute of Problems of Chemical Physics of Russian Academy of Sciences, Pokidova O. V. , Novikova V. O. ,   Institute of Problems of Chemical Physics of Russian Academy of Sciences, Emel’yanova N. S. ,   Institute of Problems of Chemical Physics of Russian Academy of Sciences,   Lomonosov Moscow State University Moscow, Psikha B. L. ,   Institute of Problems of Chemical Physics of Russian Academy of Sciences, Kulikov A. V. ,   Institute of Problems of Chemical Physics of Russian Academy of Sciences,   Lomonosov Moscow State University Moscow, Sanina N. A. ,   Institute of Problems of Chemical Physics of Russian Academy of Sciences,   Lomonosov Moscow State University Moscow,   Scientific and Educational Center “Medical Chemistry” of Mos-cow State Regional University
Published: November 2022

The process of decomposition of the nitrosyl iron complex with N-ethylthiourea ligands in various solvents (water, DMSO, ethanol) and in a mixture with hemoglobin was studied. It was shown that the complex is most stable in DMSO solution. In the presence of protein, the complex becomes a more prolonged NO donor.
SUBSTANTIATION OF MICROBIOLOGICAL SAFETY REQUIREMENTS FOR A NEW FOOD PRODUCTS OBTAINED BY MICROBIAL SYNTHESIS
Authors:   Federal Research Centre of Nutrition and Biotechnology, Minaeva L. P. , Bagryantseva O. V. ,   Federal Research Centre of Nutrition and Biotechnology, Sheveleva S. A. ,   Federal Research Centre of Nutrition and Biotechnology
Published: November 2022

The article presents an analysis of scientific data on microbial synthesis products that are used in the production of new types of food products; the main potential risks to human health in the use of products obtained using microbial synthesis with genetically modified strains have been identified; the main criteria for assessing the risk to human health of products of a new type of microbial origin and updating the microbiological safety requirements for such products are given.
THE ORIGIN AND EVOLUTION OF THE SIGNAL FUNCTION OF NITRIC OXIDE
Authors:   Federal Research Center of Biotechnology, Shumaev K. B. , Kosmachevskaya O. V. ,   Federal Research Center of Biotechnology, Nasybullina E. I. ,   Federal Research Center of Biotechnology, Topunov A. F. ,   Federal Research Center of Biotechnology
Published: November 2022

The article discusses the evolutionary aspects of the functioning of nitric oxide (NO) in various organisms. As a signaling molecule, NO is widely distributed in both prokaryotes and eukar-yotes. The diverse action of NO is due to the formation of its biologically active metabolites. The formation of these NO derivatives was associated with the evolution of energy homeosta-sis and protection of living systems from oxidative stress.
COOPERATIVE EFFECTS IN BINDING OF LIGANDS TO BIOPOLYMERS
Authors:   V.A. Engelhardt Institute of Molecular Biology, Nechipurenko Y. D. , Buchelnikov A. S. ,   Sevastopol State University, Lavrinenko I. A. ,   Voronezh State University
Published: November 2022

Models and methods of statistical thermodynamics and physical adsorption theory allow us to quantitate cooperative interactions between ligand molecules adsorbed on a macromol-ecule, in particular allosteric effects described in detail in oxygen binding to hemoglobin. We show how the Hill equation can be modified and how the Hill coefficient can be interpreted. On the other hand, the entropy of the adsorption system allows us to visualize cooperative binding processes. Cooperative interactions lead to a decrease in the entropy of the system and an increase in the information it contains.
eNOS INVOLVEMENT IN CARCINOGENESIS AND PROSPECTS FOR THE USE OF ENZYME INHIBITORS
Authors:   FSBI N.N. Blokhin NMRCO, Deryagina V. P. , Ryzhova N. I. ,   FSBI N.N. Blokhin NMRCO, Savluchinskaya L. A. ,   FSBI N.N. Blokhin NMRCO, Golubeva I. S. ,   FSBI N.N. Blokhin NMRCO, Krivosheeva L. V. ,   FSBI N.N. Blokhin NMRCO, Kirsanov K. I. ,   FSBI N.N. Blokhin NMRCO,   Peoples' Friendship University of Russia
Published: November 2022

The review discusses the literature data and the results of our own research on the role of endothelial NO synthase (eNOS) in carcinogenesis. The antitumor potential of eNOS inhibi-tors and the molecular mechanisms of their action are analyzed.
REFLECTION IN THE EEG OF DISORDERS OF CEREBRAL HEMODYNAMICS IN CHRONIC CEREBRAL ISCHEMIA IN CHILDREN
Authors:   Burdenko National Medical Research Center of Neurosurgery, Sazonova O. B. , Troshina E. M. ,   Burdenko National Medical Research Center of Neurosurgery
Published: November 2022

The paper presents the results of a study of the bioelectrical activity of the brain in 77 patients aged 2 to 18 years old with chronic cerebral ischemia, due to pathology of the main arteries of the brain, observed and operated in the Institute of Neurosurgery of N.N. Burdenko from 2012. The study showed the role of EEG in assessing the functional state of the brain in chil-dren with chronic cerebrovascular insufficiency of various etiopathogenesis in children, de-pending on the age of the child. Comparison of EEG data in extra- and intracranial cerebral vascular pathology was performed. Revealed more pronounced changes with steno-occlusive disorders in the intracranial arteries. EEG is dominated by slow forms of activity or their combination with acute potentials. Extracranial pathology led to the predominance of signs of irritation in the bioelectric picture of the brain: accelerated, pointed alpha rhythm, acute potentials, frequent fluctuations. Detailed clinical and neurophysiological examination using EEG served as a rationale for diagnosis, determination of treatment tactics and indications and contraindications for surgical intervention.
INFLUENCE OF SUBSTANCES ON FORMATION OF THERMOLIPOFUSCIN
Authors:   ICB RAS, Kovalev V. I. , Zhdanova D. Y. ,   ICB RAS, Bobkova N. V. ,   ICB RAS, Chaplygina A. V. ,   ICB RAS
Published: November 2022

The paper discusses one of the pigments of aging and pathological processes, including neu-rodegenerative ones - lipofuscin, as well as a model for its accelerated production and deg-radation methods. Original experiments on the effect of substances of different chemical na-ture on the formation of lipofuscin from rat liver mitochondria are presented.
IMMUNOCHROMATOGRAPHIC TEST SYSTEMS FOR RAPID OUT-OF-LABORATORY CONTROL OF THE COMPOSITION OF MEAT FOODS
Authors:   A.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Zvereva E. A. , Hendrickson O. D. ,   A.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Zherdev A. V. ,   A.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Dzantiev B. B. ,   A.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences
Published: November 2022

The article discusses the developed immunochromatographic test systems for the identification of raw materials in the production of meat products based on the detection of protein bi-omarkers troponin I, myoglobin, immunoglobulins. The possibilities of these systems for as-sessing the content of different types of raw materials (composition control) are considered. Data on the reproducibility of photometric measurements have been obtained. Approbation of the developed test systems for the characteristics of meat food products, evaluation of their effectiveness for composition control was carried out.
PEPTIDES ENCODED BY PRECURSOR TRANSCRIPTS OF MICRO-RNAs IN PLANTS
Authors:   Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Erokhina T. N. , Zavriev S. K. ,   Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Ryazantsev D. Y. ,   Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Morozov S. Y. ,   Belozersky Institute of Physico-Chemical Biol-ogy, Lomonosov Moscow State University
Published: November 2022

The article discusses new data obtained in the study of the functions of a conservative peptide of cabbage plants, which is encoded by the microRNA156a. Comparative analysis of the nucleotide sequences of the promoter regions of these genes allowed us to identify a highly conserved 42-residue block located before the starting point of pri-miR156a transcription at a distance of 210-260 base pairs. It was found that promoter fragments containing a highly con-served block have a significantly higher ability to bind miPEP156a in vitro. We carried out mutagenesis of a highly conserved promoter block in its central part, which includes a tetramer of TG dinucleotides. It has been shown that the introduction of mutations into the promoter tetramer of TG dinucleotides significantly reduces the affinity of the promoter DNA to miPEP156a. The miPEPs revealed in plants have been found only in dicotyledons. The question of how miPEPs are distributed in other plant taxa is very important for understanding the evo-lutionary origin of such micropeptides. As an initial approach, we searched for taxonomically conservative miPEPs in mosses, since microRNAs have been studied in a great detail in the case of Physcomitrium patens moss. For two genes in the region preceding the Ppt-pre-miR160a sequence, rather short open reading frames were found that encoded peptides having a clear similarity of amino acid sequences in the central region. Importantly, such highly con-served peptide block homologous to that encoded by Ppt-miPEP160a gene was detected in short proteins encoded in pri-miR160a in almost 20 Bryopsida mosses.
CHANGES IN THE DEUTERIUM WATER CONTENT AS A FACTOR MODULAT-ING HOMEOSTATIC PROCESSES
Authors:   A.P. Avtsyn Research Institute of Human Morphology of FSBSI «Petrovsky NRCS», Obernikhin S. S. ,   A.P. Avtsyn Research Institute of Human Morphology of FSBSI «Petrovsky NRCS», Yaglova N. V. ,   A.P. Avtsyn Research Institute of Human Morphology of FSBSI «Petrovsky NRCS», Timokhina E. P. ,   A.P. Avtsyn Research Institute of Human Morphology of FSBSI «Petrovsky NRCS», Yaglov V. V. ,   A.P. Avtsyn Research Institute of Human Morphology of FSBSI «Petrovsky NRCS»
Published: November 2022

The article discusses the role of stable hydrogen isotopes in thermogenesis and its regulation. Data on changes in body temperature and thermoregulation parameters in mice after intake of deuterium depleted water are presented.
Features of compiling metabolic correction programs for professional athletes and the possibility of their optimization using digital technologies
Authors: Yashin T. A. , Grishina Zh. V. , Kadykova A. I. , Feshchenko V. S. , Zholinsky A. V. , Pushkina T. A.
Published: November 2022

To compile a personalized program for correcting the metabolism of a professional athlete, it is necessary to take into account many factors, including age, gender, sports specialization, individual characteristics, the pathologies in the anamnesis, the stage of the athlete’s training cycle, etc. When drawing up such programs for athletes of sports national teams of the Russian Federation, a scheme for assessing the characteristics of the athlete’s body is used, the basis for which is information obtained during in-depth medical examinations of athletes conducted on the basis of clinics of the FMBA Russia. To improve the quality of personalized programs of metabolic correction in the future, it is possible to use professionally oriented reference intervals of laboratory blood parameters, as well as the results of genetic screening based on the strategy of complete exomic sequencing of the athlete’s genome. One of the ways to increase the efficiency of metabolic correction of professional athletes is the introduction of modern information technologies and the development of a modern information system based on them. The introduction of such an information system will increase the speed of primary processing of initial information about the health status of the athlete and the peculiarities of his metabolic processes, as well as partially automate the formation of individualized recommendations regarding the diet and hydratation, and the choice of metabolic correction at various stages of the sports season.
Problems of semiotics of diseases of the Achilles tendon in clinical and educational aspects
Authors: Sorokin E. P. , Sereda А. P. , Pashkova E. A. , Konovalchuk N. S. , Fomichev V. A. , Chugaev D. V. , Demyanova K. A. , Shulepov D. A.
Published: November 2022

Achilles tendon disorders are represented by a big group of heterogenous in etiology and pathogenesis conditions, that are quite frequent in patients of various age groups. The diversity of this group of orthopedic disorders and the insufficient information provided on this topic in specialized literature leads to confusion in terminology, which, in turn, leads to misunderstanding the essence of patient’s problem and to mistakes in treatment of such patients.

We carried out a content-analysis of contemporary Russian and foreign literature to summarize the existing knowledge and to create the universal nomenclature of the studied pathological conditions for further correct understanding of the problem and creation of classification of disorders and injuries of Achilles tendon.
Implementation of Features Selection Based on Dragonfly Optimization Algorithm
Authors: Mohammed Majeed Nadia , Mahmood Ramo Fawziya
Published: November 2022

Nowadays increasing dimensionality of data produces several issues in machine learning. Therefore, it is needed to decrease the number of features by choosing just the most important ones and eliminating duplicate features, also reducing the number of features that are important to the model. For this purpose, many methodologies known as Feature Selection are applied. In this study, a feature selection approach is proposed based on Swarm Intelligence methods, which search for the best points in the search area to achieve optimization. In this paper, a wrapper feature selection technique based on the Dragonfly algorithm is proposed. The dragonfly optimization technique is used to find the optimal subset of features that could accurately classify breast cancer as benign or malignant. Many times, the fitness function is defined as classification accuracy. In this study, hard vote classes are employed as a model developed to evaluate feature subsets that have been chosen. It is used as an evaluation function (fitness function) to evaluate each dragonfly in the population. The proposed ensemble hard voting classifier utilizes a combination of five machine-learning algorithms to produce a binary classification for feature selection: Support Vector Machine (SVM), K-Nearest Neighbors (K-NN), Naive Bayes (NB), Decision Tree (DT), and Random Forest (RF). According to the results of the experiments, the voting ensemble classifier has the greatest accuracy value among the single classifiers. The proposed method showed that when training the subset features, the accuracy generated by the voting classifier is high at 98.24%, whereas the training of all features achieved an accuracy of 96.49%. The proposed approach makes use of the UCI repository's Wisconsin Diagnostic Breast Cancer (WDBC) Dataset. Which consists of 569 instances and 30 features.
Study on Consumers Perceptions on “Protein Supplements” Using Big Data Analysis
Authors:   The Foodservice Management Society Of Korea, Han choon mi , Jeoung Gey-Yeoun , Hong Wan Soo
Published: November 2022

This study aimed to examine consumers perceptions on protein supplements which have newly attracted attention by using a big data analysis. To this end it collected data about the protein supplements form a variety of portal sites and drew a total of 50 key words from the data collected by using a morphological analysis. It categorized the key words into the final four constituent nodes by using the CONOCR analysis a group analysis. On the basis of such findings this study provided the right method of taking protein supplements as a final suggestion based on consumers perceptions on them.
A Study on the Difference Between Dietary Lifestyle and HMR Choice Attributes
Authors:   The Foodservice Management Society Of Korea, Choi You-Mi , kim heekee
Published: November 2022

This study aims to provide basic data that can help in planning and constructing new HMR products based on the results of identifying the choice affecting the selection attributes of HMR (Home Meal Meal) according to dietary lifestyle. The results and implications are as follows.First, as a result of cluster analysis of 6 component factors derived through factor analysis on dietary lifestyle, they were classified into 3 clusters. Second, as a result of verifying the difference in HMR food selection attributes, it was found that diversity and hygiene and cleanliness factors were statistically significant as factors that had differences by market segment.Lastly, HMR companies will need to develop a variety of quality rather than quantity products, sanitary manufacturing processes, packaging methods, store cleanliness, and employee hygiene management to be competitive.
The Qualitative Case Study on the Empowerment of College Professors Experiencing Distance Learning : Focused on F&B Subjects
Authors:   The Foodservice Management Society Of Korea, Sung HyeJin , Yoo Eunyi
Published: November 2022

The purpose of this study is to identify the changed empowerment experience and meaning of distance learning through the qualitative case study on professors conducting food and beverage practical classes, and to find ways to use teaching empowerment in future remote learning. The results of this study are as follows. First, it is said that there were many difficulties in preparing classes and knowing distance learning programs to adapt to teaching styles that most professors did not experience. Second, professors continuously try to encourage participation and communication to induce class concentration and students' independent learning during distance learning classes. The results of this study will improve the teaching empowerment of professors who conduct remote learning in food and beverage practical subjects in the future, to overcome the limitations of classes as much as possible and improving the learning effect of students.
A Phenomenological Study on the Korean Cuisine Research Class in High School Credit System Applied STEAM Education Model
Authors:   The Foodservice Management Society Of Korea, Seo Minguk , CHUNG LANA
Published: November 2022

The purpose of this study is to establish meanings, values, and implications of the STEAM education by empirically researching on the Korean cuisine STEAM education in high school credit system. The results of this study present followings. Firstly, as a result of the investigation on students’ cognition of the Korean cuisine STEAM education in high school credit system, the educational demands on ambivalent emotions and association with industry has been appeared. Secondly, changes in cognitive, affective, and behavioral areas have been shown from students who took the educational experience of the Korean cuisine STEAM education in high school credit system. Thirdly, cooperative changes and implications of the educational community through the Korean cuisine STEAM education in high school credit system have been drawn. In this study, academic implications were deduced from pedagogic meanings and values what the Korean cuisine STEAM education in high school credit system provides, and the connection between education and industry and the necessity of STEAM education were proposed as practical implications.
Effect of Culinary & Foodservice Major University Students' Restaurant Business Entrepreneurship on Their Business Start-up Preparation Behavior and Start-up Intention: Self-efficacy Control Effect
Authors:   The Foodservice Management Society Of Korea, Kim JungSoo
Published: November 2022

In this study, first, it was found that it had a significant effect on both the relationship between the technical competence, creative competence, and founder preparation behavior of college students majoring in cooking and dining. Second, it was found that it had a significant effect on both the relationship between technical competency, creative competency, and start-up intention. Third, it was found that the start-up preparation behavior had a significant effect on the start-up intention. Finally, it was verified that the group with high self-efficacy in the relationship between creative competency, start-up preparation behavior, and start-up intention had a moderating effect based on the effect of start-up will and problem-solving ability rather than the group with low self-efficacy. Therefore, it is judged that an efficient education support policy should be prepared to strengthen founder competency.
NARROW-LEAVED LUPINE GRAIN IN THE FEEDING OF YOUNG CATTLE
Authors: BESARAB G. V. , PILYUK N. V. , TKACHEVA I. V. , KARPENIA М. М. , LEVKIN E. A. , KARABANOVA V. N. , SUCHKOVA I. V. , BUKAS V. V. , KARELIN V. V. , TOMCHUK V. A. , KARPOVSKY V. I. , TROKOS V. A. , DANCHUK V. V. , KLADNITSKA L. V.
Published: November 2022

Lack of important nutrients such as protein, macro- and microelements in diets leads to lower efficiency of feed use, shortage of a significant part of livestock products and increase in their cost. The article contains the materials of research, the purpose of which was to develop protein-vitamin-mineral supplements and to study the effectiveness of feeding them as part of grain forage to young cattle. It has been established

that the inclusion of new protein-vitamin-mineral supplements in the feed ration of animals has a positive effect on the palatability of feed, digestion processes, metabolism and animal health, as well as promotes getting average daily gain of 629-710 g with feed consumption of 8,77-9,97 feed units per 1 kg of gain and reduces feed costs by 20%.
ADVANTAGES OF ESTIMATING BREEDING VALUE OF MILK PRODUCTIVITY TRAITS OF CATTLE BY THE BLUP METHOD
Authors: BIAROZAVIK R. V. , KHRAMCHANKA N. M. , MAKARA E R. , LOSHCHININ I. V.
Published: November 2022

The article presents a comparative analysis of the currently used and promising methods of estimating the breeding value of milk productivity traits. The ВLUP AM method was found to be 12-17% more accurate than the daughter-herdmate comparison method used, with differences decreasing as the accuracy of estimation increases due to involvement of a large number of daughters estimated, but remaining within 6-10%. The advantages of the BLUP AM methodology over the current methodology were identified.
MEAT TRAITS OF SHEEP GENOTYPES BRED IN THE REPUBLIC OF BELARUS
Authors: GREKOVA I. E. , HERMAN Y. I.
Published: November 2022

The article presents data on meat productivity and meat quality of sheep of P×P and (R×P)×P genotypes. Scientific research was carried out in Combine “Vostok” JSC of Gomel district, in the laboratory for feed production technology and biochemical

analysis and the laboratory for horse, fur and small animal breeding of the RUE “Scientific and Practical Center of the National Academy of Sciences of Belarus for Animal Breeding”. It was found that control slaughter parameters in purebred animals were better than in crossbred animals, since the Precoce is a specialized meat breed and the Romanovskaya is a wool breed. The difference in the indices of physicochemical properties of the longissimus dorsi muscle in the studied genotypes is insignificant and unreliable. However, in terms of mass fraction of fat, color intensity and waterholding capacity, the crossbred young animals were ahead of the purebred ones by 1.33%, 6.67 extinction units and 12.12%, respectively. The results of nutritional value and organoleptic evaluation of mutton have shown that meat and broth obtained from crossbred animals have 0.1 points better nutritional quality compared to purebred counterparts.
SPECTRAL EFFICIENCY OF THE ACTIVE MEDIUM Ti:SAPPHIRE PUMPING BY AlInGaN LED EMISSION
Authors: Aladov A. V. , Zakgeim A. L. , Ivanov A. E. , Chernyakov A. E.
Published: November 2022

The electroluminescent characteristics of powerful AlInGaN LEDs in the regime of high-pulsed current are investigated. The current dependencies of power and emission spectra of blue-green LEDs are established in their relationship with the efficiency of active medium Ti:Sapphire pumping. The reached values of the optical pumping power density using LEDs are estimated.
FLUORESCENT CHARACTERISTICS OF HOECHST 33258 COMPLEXES WITH SERUM ALBUMIN AND DNA
Authors: Antonyan A. P. , Parsadanyan M. A. , Petrosyan N. H. , Vardevanyan P. O.
Published: November 2022

We study the interaction of the bisbenzimodazole compound Hoechst 33258 with bovine serum albumin and calf thymus DNA by the fluorescence spectroscopy method. The fluorescence spectra of the complexes are obtained. Based on their maxima, the dependence curves of the fluorescence intensities of complexes of this ligand with protein and DNA on the ratio r = macromolecule/ligand are constructed. It is shown that the

dependence curve in the case of albumin decreases at low protein concentrations and increases at its high concentrations. In the case of DNA, this curve increases significantly. This fact is due to the binding of the ligand to both DNA and albumin.
REALIZATION OF LOGICAL OPERATIONS WITH IMAGES IN ACCUMULATED ECHOHOLOGRAPHY
Authors: Garnaeva G. I. , Nefediev L. A. , Nizamova E. I.
Published: November 2022

The possibility of implementing logical operations for images using accumulated echo-hologram with or without phase difference between pairs of exciting pulses is considered. The possibility for performing a number of logical operations with images in a nano time domain (union of sets, difference of sets, intersection of sets, symmetric difference) is show, which leads to appropriate filtering and image processing.
MID-IR RANGE QUANTUM CASCADE LASERS IN COMPACT OPTOACOUSTIC GAS ANALYZERS
Authors: Kolker D. B. , Sherstov I. V. , Boiko A. A. , Kostyukova N. Yu. , Erushin E. Yu. , Pavluck A. V.
Published: November 2022

The choice of the generation modes of quantum cascade lasers for optical-acoustic sensors of methan and ammonia is substantiated and the tuning and output characteristics of these lasers depending on the current and temperature are given. The results of experiments on studying the concentration sensitivity of working samples of devices developed on the basis of these lasers and ready for testing are presented. It is shown that the linear dynamic range of methane concentration measurement using the optoacoustic gas analyzer under study was approximately four decades: from ~0.3 to ~2000–3000 ppm CH4.
RAMAN SPECTRА OF SILICON/GERMANIUM ALLOY THIN FILMS BASED ON POROUS SILICON
Authors: Chubenko E. B. , Grevtsov N. L. , Bondarenko V. P. , Gavrilin I. M. , Pavlikov A. V. , Dronov A. A. , Volkova L. S. , Gavrilov S. A.
Published: November 2022

The regularities of composition changes of silicon/germanium alloy thin films formed on a monocrystalline silicon substrate by electrochemical deposition of germanium into a porous silicon matrix with subsequent rapid thermal annealing (RTA) at a temperature of 750–950°C are studied. An analysis of the samples by Raman spectroscopy showed that an increase of RTA temperature leads to a decrease in the germanium concentration in the formed film. A decrease of the RTA duration at a given temperature makes it possible to obtain films with a higher concentration of germanium and to control the composition of thin silicon/germanium alloy films formed by changing the temperature and duration of RTA. The obtained results on controlling the composition of silicon/germanium alloy films can be used to create functional electronic devices, thermoelectric power converters, and optoelectronic devices.
OPTICAL PROPERTIES OF RARE-EARTH ELEMENTS OXOSELENIDES OF OPTICAL PURITY
Authors: Malyutina-Bronskaya V. V. , Soroka A. S. , Senkevich D. V. , Tarasenko M. S. , Ryadun A. A. , Naumov N. G.
Published: November 2022

The optical properties of doped oxoselenides of rare-earth elements of optical purity RE2O2Se:RE' (RE = Gd, Y; RE' = Sm, Tb) are studied. Photoluminescent properties of oxoselenides of rare earth elements of optical purity in the form of powders and thin films demonstrate the fundamental possibility of using them as a scintillation material for detectors of ultraviolet or ionizing radiation.
INFRARED REFLECTION SPECTRA OF MnxFe1–xIn2S4 SOLID SOLUTIONS
Authors: Bodnar I. V. , Feshchenko A. A. , Khoroshko V. V. , Karoza A. G.
Published: November 2022

Large-block crystals of FeIn2S4, MnIn2S4 ternary compounds and MnxFe1–xIn2S4 solid solutions are grown by the method of directional crystallization (horizontal Bridgman method). The structure of the obtained crystals is determined by X-ray diffraction analysis. It is shown that both the starting compounds and solid solutions based on them crystallize in the cubic spinel structure. The IR reflection spectra in the frequency range 50–500 cm–1 of crystals of ternary compounds FeIn2S4, MnIn2S4 and solid solutions MnxFe1–xIn2S4 are studied. The frequencies of transverse (ωTO) and longitudinal (ωLO) optical phonons are determined. The concentration dependences of these parameters are plotted and the nature of their behavior is established.
INFLUENCE OF AUTOLYTIC FLOUR ACTIVITY ON VOLUME OF RYE BAKERY PRODUCTS
Authors: Laptenok N. S. , Ivashkevich T. V.
Published: November 2022

The article presents studies of the quality of rye bakery products made from seeded rye flour with different indicators of autolytic activity and falling numbers. The physicochemical indicators of the quality of finished products (moisture, acidity, porosity) have been determined and the volume of molded products. The issues of the influence of autolytic activity on the volume and dimensional stability of finished bakery products are considered. The dynamics of changes in the volume of tinned breads from seeded rye flour with the same falling number depending on the autolytic activity of seeded rye flour was revealed.
YEAST CELL WALLS ARE AN EFFECTIVE MYCOTOXIN ADSORBENT IN FEED
Authors: Marhunova А. M. , Solovyov V. V.
Published: November 2022

In the world, serious attention is paid to the development of modern and effective methods for disinfecting feed from mycotoxins. Due to the characteristic weather conditions in the Republic of Belarus, almost all large livestock complexes and private farms are faced with the problem of mycotoxicosis in animals and birds, and this, in turn, has a huge impact on feed safety and, subsequently, on food safety. The problem

of mycotoxins in feed can be solved by using various adsorbents. A mycotoxin adsorbent based on yeast cell walls is suitable for the role of such adsorbents. This article presents the results of studies on the physicochemical properties of yeast cell walls and their adsorption capacity by high performance liquid chromatography, using a reference sample of Trylogy multitoxins, in relation to such mycotoxins as aflatoxin B1, ochratoxin A,

zearalenone, deoxynivalenol. The obtained results show that yeast cell walls have good adsorption capacity for high molecular weight mycotoxins and poorly adsorb low molecular weight mycotoxins.
FACTORS INFLUENCING THE BIOLOGICAL AND MORPHOMETRIC PARAMETERS OF HETERAKIS GALLINARUM EGGS (GMELIN, 1790)
Authors: Saroka A. M.
Published: November 2022

The article presents the results of the research on the peculiarities of embryo and morphometric development

of the eggs isolated from the gonads of female nematodes Heterakis gallinarum that parasitize turkeys and hens at different

intensities of invasion in case of mono-and mixed forms of helminth infections. It was established that the eggs of H. gallinarum became invasive at 30 °C for 7 days, their survival rate in the laboratory conditions was: 80,67±2,08 % (turkeys), 84±3 % (chickens). The morphometric parameters of eggs excreted by mature H. gallinarum females are objectively influenced by such factors as the stage of biological cycle, the intensity of invasion, the type of host.
ON THE SANITARY CONDITION OF THE MILK TRANSFER SYSTEM OF MILKING MACHINES
Authors: Kazheko O. A. , Baranovsky M. V. , Musica A. A. , Vysotsky A. E.
Published: November 2022

The article contains a review material on the level of microbial contamination of the milk-carrying sections of the transport system of the 2ADS-N (milk pipeline), Merry-go-round, Herringbone and Parallel milking plants.

The differences in the level of bacterial contamination of the surfaces of components and parts in contact with milk, depending on the volume and structural features and types of materials used for their production, have been noted.

The critical contamination limits have been identified that allow taking timely corrective actions to mitigate potentially

dangerous biological risks in accordance with the HACCP principles.

It is indicated on the necessity of investigation of microbial contamination of milk hoses for pumping milk from the milking parlor to the cooling tank and milk hoses for pumping milk from the cooling tank to the milk delivery truck, as well as the correction of sanitary treatment regimes for these types of products.
Pengaruh EPS, ROA dan ROE terhadap Harga Saham pada Perusahaan Asuransi yang terdaftar di Bursa Efek Indonesia Periode 2015-2019
Authors: Pratiwi Tiara Ivandri , Rivandi Muhammad
Published: November 2022

The stock price is a factor that is very useful for a company and is something that must be kept in mind for an investor. The stock price can arise from the level of supply and demand for a stock. This study aims to determine and analyze the effect of EPS, ROA, and ROE variables partially on stock prices, as well as to determine which variables have the most dominant influence on stock prices in insurance companies. The data processed is secondary data from the annual reports of 11 insurance companies listed on the IDX in 2015-2019 were taken through purposive sampling. The method used in this research is the panel data regression analysis method using Eviews version 8.0. The results of this study indicate that: Earning Per Share has a positive effect on stock prices, Return on Asset and Return on equity has no effect on stock prices
Pengaruh Gaya Kepemimpinan Transformasional, Kepuasan Kerja dan Komitmen Organisasi Terhadap Turnover Intention
Authors: Suhakim Ade Imam , Badrianto Yuan
Published: November 2022

Turnover intention pada dasarnya adalah sama dengan keinginan berpindah karyawan dari satu tempat ke tempat kerja yang lainnya. Turnover intention dapat menjadi masalah yang serius bagi sebuah perusahaan yaitu meningkatnya biaya pengeluaran untuk penerimaan tenaga kerja baru, seleksi, pelatihan serta terhambatnya target yang seharusnya dicapai oleh perusahaan. Peningkatan turnover intention pada penelitian ini difokuskan pada PT. PND sebagai objek penelitian, kerena setiap tahun turnover intention mengalami peningkatan. Penelitian ini bertujuan untuk mengujiapakah terdapat pengaruh gaya kepemimpinan transformasional, kepuasan kerja dan komitmen organisasi terhadap turnover itention karyawan PT. PND . Metode pengambilan sampel yang digunakan adalah nonprobability sampling yaitu dengan metode sampling jenuh. Metode yang digunakan dalam penelitian ini adalah dengan metode penelitian kuantitatif dengan bantuan program statistik SPSS version 22 for windows (Statistical Package For Social Sciences). Hasil dari penelitian ini membuktikan bahwa terdapat pengaruh negatif dan signifikan antara gaya kepemimpinan transformasional dengan turnover intention karyawan, terdapat pengaruh positif dan signifikan antara kepuasan kerja dengan turnover intention karyawan, terdapat pengaruh positif dan signifikan antara komitmen organisasi dengan turnover intention karyawan.