bluuebunny/crossref_metadata_2025 huggingface dataset:
Operating Mechanism of University Innovation and Entrepreneurship Education and Its Contribution to Regional Economy
Authors: Fu Yuanyuan , Li Qian , Chang Yuanyuan
Published: July 2022

China has already ushered in a new economic development stage and its main driving force for the high-quality economic development has gradually shifted to innovation and entrepreneurship and high-level innovative talents. Existing research has ignored to some extent the discussion on regional differences and underdeveloped areas. To this end, this paper studies the operating mechanism of university innovation and entrepreneurship education and its contribution to regional economy. First, based on the theories of human capital and regional economic development, a labor output elasticity estimation model was constructed for regional human resources, to measure the contribution rate of the innovation and entrepreneurship education in regional universities to regional economic development. Considering the complex relationship between university innovation and entrepreneurship education and regional economic development and fluctuations, a suitable VAR model was constructed based on the economic theory to analyze and empirically study the relationship between the two. Finally, the calculation results of the contribution rates of the university innovation and entrepreneurship education in the region and various sub-regions were provided based on the experiment, which verified the effectiveness of the calculation method and analysis model.
Determinants of Teachers’ Continuance Intention to Adopt Virtual Learning Environment within Malaysian Schools
Authors: Luqman Hakim Satiman  , Nadiatulhuda Zulkifli
Published: July 2022

The adoption of virtual learning environment (VLE) has started to gain serious attention worldwide including Malaysia, where its usage during the Covid-19 pandemic outbreak has become a necessity. Nevertheless, the extent to which teachers have adopted the VLE and which factors are most influencing the continuance intention to adopt VLE post pandemic remain ambiguous. The objective of this conceptual study is to provide a conceptual framework in investigating the factors that most influence the continuance intention to adopt VLE among teacher in Malaysian school. This study overviews several important variables that may influence the continuance intention to adopt VLE from three contexts (technology, organization and environment) which include relative advantage, compatibility. observability, technological infrastructure, school support, technical support and government support. Finally, this study can improve the understanding about which factors that may encourage or hinder the continuance intention to adopt VLE in Malaysian school to enhance education quality for societal change.
Performance Analysis of Soil Health Classifiers Using Data Analytics Tools and Techniques for Best Model and Tool Selection
Authors: Sushma Rahul Vispute  , Madan Lal Saini
Published: July 2022

One of the most crucial stages in the building of a Machine Learning (ML) model is the evaluation and analysis of classifier model performance. The agricultural sector is the economic backbone of India and needs extensions to provide solutions to the problems faced by the farmers. This paper presents agriculture soil health analysis using Machine Learning approaches for best model and tool selection and also bibliometric analysis to identify different sources and author’s keywords for finding the area of focus for proposed work.  Models are built on SK-Learn, KNIME, WEKA and Rapid Miner tools using different ML algorithms. Nave Bayes, Random Forest (RF), Decision Tree (DT), Ensemble learning (EL), and k-Nearest Neighbor (KNN) are used to analyze soil data on these tools. Results show that Decision Tree model outperforms other algorithms, followed by RF algorithm which is a set of multiple Decision tree algorithms and SK-Learn tool gives better accuracy followed by WEKA tool then KNIME tool. Maximum accuracy obtained by Decision Tree algorithm is 98.40% using SK-Learn followed by KNIME tool with 73.07%, Maximum accuracy obtained by Naïve Bayes algorithm is 69.50% using SK-Learn followed by KNIME tool with 68.14%, maximum accuracy obtained by Random Forest algorithm is 85.00% using SK-Learn followed by 73.06% using WEKA tool, maximum accuracy obtained by Ensemble algorithm is 89.00% using SK-Learn followed by 73.06% using WEKA tool and for KNN it is 95.50% using SK-Learn followed by 71.85% using WEKA tool.
L’autonomie du laid dans quelques œuvres contemporaines américaines
Authors: Sagaert Claudine
Published: July 2022

La thèse débattue dans cet article porte sur l’autonomie de la laideur dans l’art contemporain. De manière certes non-exhaustive, cette analyse ambitionne de montrer, à partir de quelques œuvres emblématiques de plasticiens d’Amérique du nord et d’Amérique du sud, comment ce qui jusqu’alors était en marge de toute œuvre, va acquérir notamment dans les dernières décennies du XXe siècle une importance de premier plan. En entraînant un bouleversement dans l’ordre des valeurs, en fissurant l’alliance du laid, du mal et du faux, la laideur (en tant que sujet de l’œuvre, processus de création et stimulation d’affects négatifs) va s’affirmer en tant que puissance capable d’incarner d’autres aspirations. La laideur ne sera plus alors cantonnée à figurer ce qui ne devrait pas être mais à transcrire l’apparaître de ce qui est. Dérangeantes, ces productions feront du laid le véhicule d’une certaine véridiction. Dénonçant l’ignominie propre à certains types de rapports intersubjectifs, ces productions plastiques en portraiturant une humanité abjecte se voudront les déclencheurs d’un possible changement. Ce sont ces différentes facettes de la laideur présentes de manière novatrice au cœur des travaux de plasticiens d’Amérique du nord et d’Amérique du sud que cet article propose d’explorer.
Die wohnwerkstätten der silbererzminen von Le Colombier (Ardèche)
Authors: Larousse Nicolas Minvielle , Commandré Isabelle , Fabre Magali , Flament Julien , Gratuze Bernard , Guionova Guergana , Ros Jérôme , Thuaudet Olivier
Published: July 2022

Der Hügel von Le Colombier im Tal von Chassezac (Ardèche, Frankreich) gelegen, wurde im Hochmittelalter (11.-12. Jh.) zeitweilig besiedelt, um dort eine Ader mit silberhaltigem Bleierz abzubauen. In der Nähe der Abbaustellen wurde eine Siedlung errichtet. Nach mehreren Jahren Ausgrabung wird hier eine Bilanz gezogen, um die Besiedlung des Hügels zu beschreiben und ihre Funktionen näher zu bestimmen. Ausgehend von einer morphologischen Untersuchung, einer Bauuntersuchung und einer Untersuchung des in der Siedlung geborgenen Fundmaterials (Steingeräte, Schlackenabfälle, Keramik, Glas, Fauna, Pflanzenressourcen, gefertigte Gegenstände) war es möglich, eine Interpretation als Abbaustelle vorzuschlagen. Die Siedlung wurde im Zusammenhang mit der Aufbereitung und Weiterverarbeitung des Erzes gegründet und die den Arbeitern als Wohnwerkstatt dienenden Gebäude wurden regelmäßig von kleinen Bergbaubetrieben genutzt.
An archaeological window into the town of Moissac (Tarn-et-Garonne) from the 12th to the 19th century [abridged version]
Authors: Lefebvre Bastien
Published: July 2022

Between 2015 and 2018, several programmed excavation campaigns were undertaken, as part of a research on the formation of the agglomeration, south of the Saint-Pierre de Moissac monastery. The significant stratigraphic power, the large quantity of structures and the very good preservation of organic materials due to the humid subsoil have made it possible to document the dynamics of a domestic occupation between the 12th and 19th centuries. If one of the main results of this research was to highlight that the development of the settlement is probably not prior to the second half of the 12th century, the data collected concerning the domestic occupation proved to be rich, with the discovery of a great variety of furniture in a discarded position, and the discovery of original structures, such as a large lever press built at the end of the 13th century.
Una ventana arqueológica sobre la aglomeración de Moissac (Tarn-et-Garonne) entre los siglos XII y XIX [artículo resumido]
Authors: Lefebvre Bastien
Published: July 2022

Entre 2015 y 2018, se realizaron varias campañas de excavación programadas en el marco de la investigación sobre la formación de la aglomeración al sur del monasterio de Saint-Pierre de Moissac. La importante potencia estratigráfica, la gran cantidad de estructuras y la muy buena conservación de los materiales orgánicos debido al subsuelo húmedo permitieron documentar la dinámica de ocupación doméstica en un sector de la ciudad entre los siglos XI y XIX. Aunque uno de los principales resultados de esta investigación fue demostrar que el desarrollo del asentamiento probablemente no fue anterior a la segunda mitad del siglo XI, los datos recogidos sobre la ocupación doméstica resultaron ser ricos, con el descubrimiento de una gran variedad de muebles en posición de descarte, y el hallazgo de estructuras originales, como una gran prensa de palanca construida a finales del siglo XIII.
¿ Un simple montón de huesos ? El complejo funcionamiento de un osario medieval en el cementerio parroquial de la iglesia de Notre-Dame de Boulogne-sur-Mer (Pas-de-Calais) [versión abreviada]
Authors: Blamangin Olivier , Oudry Sophie , Kacki Sacha
Published: July 2022

La recogida y el depósito secundario de huesos era una práctica funeraria habitual en la gestión de los espacios del cementerio medieval. Las acumulaciones de huesos resultantes rara vez se benefician de una cuidadosa excavación y estudio arqueológico. La reciente excavación de una fosa de osario en el cementerio parroquial de la iglesia de Notre-Dame de Boulogne-sur-Mer demuestra, sin embargo, que este tipo de estructuras no puede reducirse a la simple expresión de una gestión pragmática de los restos humanos. En el ejemplo de Boulogne, bien fechado en el siglo XIV por los análisis del 14C, se realizaron cuatro enterramientos primarios en el osario – tres niños pequeños, dos de los cuales fueron colocados en ataúdes, y un adulto colocado boca abajo –, lo que atestigua la coexistencia de dos funciones, dos "intenciones" y varios "tiempos funerarios" en el funcionamiento de la estructura. Los resultados obtenidos nos llevan a discutir el significado que debe darse a estos gestos funerarios atípicos que a veces se encuentran en otros yacimientos.
Del bosque al edificio. Estudio pluridisciplinar de las cubiertas de madera en el Sureste de Francia (siglos XII-XIX) [artículo resumido]
Authors: Burri Sylvain , Labbas Vincent , Bernardi Philippe
Published: July 2022

Aunque cada vez se tiene más en cuenta el papel de la madera en la arquitectura medieval y moderna, su uso como material de cubierta es todavía poco conocido. En la Provenza, percibida durante mucho tiempo como la tierra del azulejo, la madera se consideraba marginal y se limitaba a las viviendas de montaña. Este artículo pretende situar estos materiales de cubierta en el lugar que les corresponde en la economía y las técnicas de la construcción, a través de una investigación multidisciplinar que combina los puntos de vista y los métodos de la historia, la arqueología de la construcción y la dendrocronología. Este enfoque global e integrado contribuye a la historia de las técnicas de construcción identificando los diferentes materiales de madera utilizados y reconstruyendo la cadena de producción, desde la adquisición de su materia prima en el bosque hasta su uso y vida (reparación, reutilización) en los armazones de los edificios, tanto en la ciudad como en el campo, tanto en la montaña como en la llanura. Por último, contribuye a la renovación de los conocimientos sobre la economía sudalpina analizando los mercados económicos y los entornos sociológicos en los que se integran estos productos.
Discours de Guillaume Pepy, président de la SNCF Bobigny 25 janvier 2011
Authors: Delmaire Danielle
Published: July 2022

Le 25 janvier 2011, Guillaume Pepy, président de la SNCF prononçait un discours, dans la gare désaffectée de Bobigny d’où sont partis des convois de la déportation des Juifs de juillet 1943 à août 1944. C’était à l’occasion de l’inauguration d’un lieu de mémoire. Ce discours, analysé ici, reconnaît l’implication de la SNCF dans la formation des convois mais aussi le courage de cheminots rebelles à l’occupation.
Les cheminots Justes parmi les Nations, essai de prosopographie
Authors: Thévenet Laurent
Published: July 2022

Au cours de l’Occupation allemande, des cheminots aident, cachent et sauvent des enfants et des familles juives persécutés et menacés de déportation. 55 d’entre eux seront reconnus Justes parmi les Nations. Cet essai de prosopographie présente ces Justes et résume des sauvetages selon les périodes et leur localisation. Il éclaire par des situations vécues, les motivations de ces gestes de solidarité : l’engagement politique, la foi ou la pratique religieuse, tout comme les relations de voisinage qui ont pu jouer un rôle décisif dans la prise de décision. Le regard porte également sur certains Justes et tout particulièrement sur les femmes dont le rôle apparaît souvent déterminant.
Students' Writing Engagement
Authors: Ives Samantha T. , Parsons Seth A. , Marine Jonathan , Rogers Paul M. , Horton Ashlee , Young Chase
Published: July 2022

While student engagement is a well-researched educational construct that is positively associated with student performance, writing engagement has received less attention. Drawing on engagement research generally and reading engagement research specifically, the authors present writing engagement as a multidimensional construct including affective, behavioral, cognitive, and social components with the potential to support students at all stages of the writing process in equitable and culturally responsive ways. In this chapter, the authors trace the origins of the writing process movement to support teachers in designing instruction that encourages student participation in writing in and beyond the classroom. By attending to student engagement at each stage in the writing process, the authors argue that teachers and future researchers can account for how students feel, act, think, and interact throughout the writing process and in doing so construct classroom practices that appeal to all students and promote their growth.
Youth Re-Writing of Self
Authors: Wilder Phillip
Published: July 2022

Given today's social and political milieu, disciplinary writing in secondary schools must address systemic violence and the increased disconnection amongst youth from self and communities. The chapter will illuminate ways writing pedagogy in secondary school disciplines—with its privileging of dominant writing genres and narrow conceptions of disciplinary literacies—perpetuate youth disconnection. Then, it proposes disciplinary writing—grounded in principles of nonviolent communication and critical consciousness—can support a literacy of being where youth unlearn culturally-conditioned, deleterious narratives of self and become a source of peace and justice within communities. Secondary school writing can cultivate agentive spaces for youth to awaken to the sources of societal, communal, and personal violence and rewrite themselves with greater compassion, authenticity, and personal power.
Challenges of Argumentative Writing Instruction in Higher Education
Authors: Duriez Rafael Santiago Meza , Orellana Pelusa
Published: July 2022

This chapter describes the implementation of an evidence-based instructional framework to enhance the argumentative writing skills of undergraduate students in Nicaragua. The framework draws on the gradual release of responsibility model, Toulmin's argument model, and the writing as a community approach. The implementation failed in improving students' writing skills. However, this experience allows for an in-depth reflection on the challenges that are still present in the educational system, and which prevent university students from becoming competent writers. Shared views of writing instruction within the system, understanding how students view writing in their lives, and the cultural contextualization of promising instructional approaches are aspects that must be addressed before engaging students in new methodologies. The authors discuss how an intervention that was proven ineffective in this context can enact a reflection as to how teachers in countries with insufficient evidence can find better solutions to provide quality instruction.
Converting Course Material to Educational Escape Room Formats
Authors: Ross Robert , Hall Richard , Ross Sarah Lynne
Published: July 2022

Game-based learning and gamification concepts are growing as educators look to engage, motivate, and create memorable learning experiences for their students. In this chapter, the authors provide a primer to bring teachers and academics up to date on developing educational escape rooms for their classrooms. Hence, this chapter gives an overview of what education escape rooms are, how they can be run, narratives, the pedagogical purpose of the escape room, and how puzzles can be generated. The chapter provides categories of puzzle types with examples and concludes with a STEM-based escape room activity targeted toward secondary school students.
Development of Computer Games by Students
Authors: Minnegalieva Chulpan
Published: July 2022

People have a different attitude towards computer games – from their complete rejection to delight. However, representatives of different professions agree that computer games can and should be used with benefit. This chapter describes practical tasks related to developing computer games in students' education. Tasks of that type are offered to students studying information technology. Game development uses modern platforms that provide ample opportunities. Students develop 3D models, write scripts, and research interaction principles between different applications. Such tasks will help protect the younger generation from misuse of computer games, improve programming and modeling skills, and develop spatial thinking and creativity.
Gamification Framework
Authors: Kutty Asha S. , Joy Manu Melwin
Published: July 2022

The effectiveness of any teaching-learning process (TLP) can be evaluated based on results obtained after using it. Any learning result relies upon the pedagogical methods adopted to teach learners. The more the technique's suitability, the better will be the results. Game-based learning is where game features and principles are implanted within learning activities. Game-based learning is also an effective learning technique in which games boost student learning. Game-based learning (GBL) brings advancement, experimentation, and disclosure of internal ability in learners. For the educators, it creates original thoughts and ways to deal with the teaching-learning process, allowing instructors to learn new methodologies lined up with research on how students learn. This chapter attempts to sort out the requirement for game-based learning as a creative educating approach. The significant finding of this chapter is a conceptual framework that will enable researchers to identify critical factors for the successful implementation of GBL.
Implementing Technology-Mediated Task-Based Language Teaching in an EFL Writing Course
Authors: Wang Yi-Chien
Published: July 2022

This study explored the effects of technology-mediated task-based language teaching (TMTBLT) in an English as a foreign language (EFL) writing course on students’ descriptive writing performance. A quasi-experiment was conducted. Students in two writing courses were recruited and randomly assigned to an experimental or control group. The participants in the experimental group were engaged in the technology-mediated writing task of transforming their descriptive writing assignment, in which they introduced local tourist attractions, into videos to exchange online with foreign virtual peers. A mixed-methods research approach was adopted to analyze the data collected from participants’ compositions and self-reflections. The results revealed that TMTBLT was effective in developing EFL students’ descriptive writing proficiency. In addition to improving their writing, the students enjoyed participating in the task and used multiple skills. The implications of this study for TMTBLT in EFL writing teaching practices are also discussed.
Anticancer activity of Δ9-tetrahydrocannabinol and cannabinol in vitro and in human lung cancer xenograft
Authors: Leelawat Surang , Leelawat Kawin , Wannakup Thaniya , Saingam Worawan , Khamthong Nanthaphong , Madaka Fameera , Maha Athip , Pathompak Patamaporn , Sueree Lukman , Songsak Thanapat
Published: July 2022

Objective:

To investigate the effects of Δ9-tetrahydrocannabinol, the principal psychoactive compound of Cannabis sativa, and cannabinol, a Δ9-tetrahydrocannabinol degradative product, on human non-small cell lung cancer cells.

Methods:

Δ9-Tetrahydrocannabinol and cannabinol were tested for anticancer activity in human non-small cell lung cancer (A549) cells. The effects on cell proliferation, apoptosis, and phosphorylation profiles were examined. The effects of Δ9-tetrahydrocannabinol and cannabinol on tumor growth were also investigated using a xenograft nude mouse model. Apoptosis and targeted phosphorylation were verified by immunohistochemistry.

Results:

Δ9-Tetrahydrocannabinol and cannabinol significantly inhibited cell proliferation and increased the number of apoptotic cells in a concentration-dependent manner. The Δ9-tetrahydrocannabinol- and cannabinol-treated cells had lower levels of phosphorylated protein kinase B [AKT (S473)], glycogen synthase kinase 3 alpha/beta, and endothelial nitric oxide synthase compared to the controls. The study of xenograft mice revealed that tumors treated with 15 mg/kg Δ9-tetrahydrocannabinol or 40 mg/kg cannabinol were significantly smaller than those of the control mice. The tumor progression rates in mice treated with 15 mg/kg Δ9-tetrahydrocannabinol or 40 mg/kg cannabinol were significantly slower than in the control group.

Conclusions:

These findings indicate that Δ9-tetrahydrocannabinol and cannabinol inhibit lung cancer cell growth by inhibiting AKT and its signaling pathways, which include glycogen synthase kinase 3 alpha/beta and endothelial nitric oxide synthase.
Evaluation of non-motor symptoms in wilson disease using the parkinson's disease nonmotor symptoms questionnaire
Authors: Chakraborty Arka P. , Mukherjee Adreesh , Sarkar Sumanta , Sinharoy Uma , Biswas Atanu
Published: July 2022

Background:

There is a dearth of studies on non-motor symptoms of Wilson's disease (WD) which is primarily because of the non-availability of a suitable scale.

Objective:

To assess the suitability of the Parkinson's Disease non motor symptoms questionnaire (PD-NMS Quest) in the assessment of non-motor symptoms of WD patients.

Methods:

In this case-control study, patients of WD above ≥12 years of age diagnosed by Leipzig's criteria and age and gender-matched control subjects were recruited. Critically ill patients, patients with severe hepatic impairment, or with pure hepatic WD were excluded

.

PD-NMS Quest was applied and relevant statistical analyses were performed.

Results:

A total of 18 cases and 25 controls were studied. Patients had a mean age of 22.6 years and a median disease duration of 8 years. WD patients had higher frequencies of all NMS than controls. Drooling (P = 0.0037), dysphagia or choking (P = 0.0088), nocturia (P = 0.0471), anxiety/fear (P = 0.0337), feeling sad or blue (P = 0.0020) and falling (P = 0.0197) were significantly higher in WD patients than controls.

Conclusions:

Although many NMS of WD patients are picked up effectively with PD-NMS Quest, some of them need detail assessment including cognitive, behavioral, and psychiatric symptoms, drooling and dysphagia, sleep as well as autonomic disturbances. Questions pertaining to sexual activity may be omitted from the questionnaire.
Clinical Profile and Outcome in Patients of Complicated Urinary Tract Infections
Authors: Jindal Jyoti , Meelu Abhinav , Kaur Simran , Chahal Harmandeep Singh , Makkar Vikas , Garg Vikas
Published: July 2022

Background

Complicated urinary tract infection (cUTI) is the one which is associated with structural and functional abnormalities of the urinary tract, thus increasing the risk of infection and failure of therapy.

Aim:

This study aims to determine the risk factors, changing trends in etiology, current treatment options, and outcomes in cUTI.

Materials and Methods:

This prospective observational study was done on patients presenting with cUTI. Hematological, biochemical workup, urine routine, urine culture, blood culture, ultrasonography, and wherever necessary computerized tomography of the genitourinary tract was done. The medical/surgical interventions and outcomes in these patients were recorded.

Results:

A total of 100 patients were enrolled in the study. Diabetes mellitus was the most common risk factor present in 53%. The most common organism isolated in urine culture was Escherichia coli (48%) followed by Klebsiella pneumoniae (19%) and similar trend but lesser positive yield was there in blood culture (Escherichia coli - 26% followed by Klebsiella pneumoniae - 3%). The organisms were most susceptible to colistin/polymyxin (100%) followed by carbapenems (88%), and later were the most commonly used empirical antibiotics in our study, yielding 95% survival rate. Surgical interventions (percutaneous/endourological) were required in 28%, renal replacement therapy in 14%, intensive care in 40% and mechanical ventilation in 10%, with 4% overall mortality at the end of 1-month follow-up. The mean duration of hospital stay was 9.1 ± 2.7 days.

Conclusion

Escherichia coli was the most common organism causing cUTI, with diabetes being the most common risk factor. Most of the patients were treated with carbapenems with excellent survival outcomes.
Diagnostic Accuracy and Relationship between Optical Coherence Tomography Angiography Vessel Density and Structural/Functional Parameters in Healthy, Preperimetric, and Manifest Glaucoma Eyes
Authors: Khallouli Asma , Oueslati Yassin , Gouider Dhouha , Bouchoucha Saker , Maalej Afef , Rannen Riadh
Published: July 2022

Purpose:

To evaluate circumpapillary vessel density (cpVD) in normal subjects, preperimetric glaucoma, and manifest glaucoma, assess the relationship between cpVD and both structural and functional parameters and compare the diagnostic accuracy of the structural and vascular measurements.

Methods:

An analytical cross-sectional study of 153 eyes of 83 individuals divided into three groups: Normal subjects, preperimetric glaucoma, and manifest glaucoma. All individuals underwent standard automated perimetry, spectral-domain optical coherence tomography (SD-OCT), and OCT angiography (OCT-A) centered on the optic nerve. We assessed structural (ganglion cell complex [GCC]/retinal nerve fiber layer [RNFL]) and functional parameters (mean deviation [MD]/loss variance [LV]).

Results:

Thirty-three normal subjects (66 eyes), 18 patients (30 eyes) with preperimetric glaucoma, and 32 patients (57 eyes) with manifest primary open-angle glaucoma were enrolled. The comparative study of cpVD showed a significant difference comparing glaucomatous subjects versus preperimetric glaucoma (P = 0.025) groups and normal subjects (P < 0.001). The cpVD was strongly correlated with functional parameters, MD, and LV (P < 0.001). Furthermore, cpVD was better correlated with RNFL (P < 0.001) than GCC (P < 0.001). Best regression was observed with mean RNFL (R2 = 0.752). The cpVD has a higher diagnostic value than RNFL and GCC, only between preperimetric and manifest glaucoma.

Conclusions:

Circumpapillary vessel damages seem to be less prominent, as it was seen only for the manifest glaucoma group. Microvascular changes appear to occur secondary to RNFL and GCC damages. They seem to be well correlated with visual function. Therefore, OCT-A is not as sensitive as SD-OCT in detecting early structural alterations.
Experimental animal models and evaluation techniques in intracerebral hemorrhage
Authors: Thangameeran Shaik Ismail Mohammed , Pang Cheng-Yoong , Lee Chien-Hui , Tsai Sheng-Tzung , Hu Wei-Fen , Liew Hock-Kean
Published: July 2022

Intracerebral hemorrhage (ICH) is the most lethal type of cerebral stroke without effective therapy. Although clinical trials with various surgeries have been conducted, none have improved clinical outcomes compared to the current medical management for ICH. Several ICH animal models, including autologous blood injection, collagenase injection, thrombin injection, and microballoon inflation methods, have been developed to elucidate the underlying mechanisms of ICH-induced brain injury. These models could also be used for discovering new therapy for ICH preclinically. We summarize the existing ICH animal models and the evaluation parameters used to measure the disease outcomes. We conclude that these models, resembling the different aspects of ICH pathogenesis, have their advantages and disadvantages. None of the current models closely represent the severity of ICH seen in clinical settings. More appropriate models are needed to streamline ICH’s clinical outcomes and be used for validating newly developed treatment protocols.
Management of Parkinson’s Disease Psychosis
Authors: Elsibai Hanan , Kualleny Mena , Fandy Tamer E.
Published: July 2022

Objectives To discuss therapeutic management of Parkinson’s disease psychosis (PDP) and the burdens associated with it. Parkinson’s disease (PD) is an incurable, progressive, and devastating neurodegenerative disease. The prolonged use of dopamine agonists to
improve the motor symptoms of PD may result in nonmotor complications such as psychosis. These complications are as devastating as the motor symptoms that accompany PD. PDP is associated with financial burden for patients and health care organizations. Data Sources PubMed
search using the phrases Parkinson’s disease, Parkinson’s disease psychosis, clozapine, quetiapine, and "pimavanserin." Conclusion Pimavanserin is the only US Food and Drug Administration approved drug for the management of hallucinations and delusions
associated with PD psychosis. The off-label use of clozapine and quetiapine has demonstrated clinical utility; however, there is still a need for the development of novel therapeutic molecules to avoid side effects associated with current therapeutic options and reduce the burdens of patients,
caregivers, and health care institutions.
Autoregressive Modeling based ECG Cardiac Arrhythmias’ Database System
Authors: Hamarsheh Qadri
Published: July 2022

This article proposes an ECG (electrocardiography) database system based on linear filtering, wavelet transform, PSD analysis, and adaptive AR modeling technologies to distinguish 19 ECG beat types for classification. This paper uses the Savitzky-Golay filter and wavelet transform for noise reduction, and wavelet analysis and AR modeling techniques for feature extraction to design a database system of AR coefficients describing the ECG signals with different arrhythmia types. In the experimental part of this work, the proposed algorithm performance is evaluated using an ECG dataset containing 19 different types including normal sinus rhythm, atrial premature contraction, ventricular premature contraction, ventricular tachycardia, ventricular fibrillation, supraventricular tachycardia, and other types from the MIT-BIH Arrhythmia Database. The simulation is performed in a MATLAB environment.
Epigenetic effects of climate on dairy parameters of Prim’Holstein breed in west coast Algeria
Authors: YEROU Houari , ZOGHLAMI Morad , MESKINI Zakaria , HOMRANI Abdelkader , YEROU Walid
Published: July 2022

This research aimed to evaluate the effect of the epigenetic climatic factor of heat stress expressed by the THI on some parameters of milk production of Prim'Holsteins cows kept in the climate of the Algerian West coast. The THI was used as an indicator of the heat stress threshold. A sample of 75 lactating cows was divided into three groups according to THI level. The cows of group 1, with severe stress (THI>78), those of group 2, with light stress (THI 72-78), and those of group 3 in thermal comfort (THI<72). The daily milk production (DMY), the Physico-chemical quality (TB, TP, and EST), and the hygienic quality (total flora FMAT) of raw milk showed a decrease with the increase of the THI threshold. A significant effect (p<0.05) of heat stress is recorded on the Physico-chemical and microbiological parameters of milk. The FMAT count values of raw milk samples were highest for groups 1 and 2, while a low bacterial load was recorded for group 3 (THI<72). Heat stress had a negative impact on the performance of Prim'Holsteins cows. These preliminary results show the severity of the negative impact of heat stress in the littoral region on the production and the physicochemical and hygienic quality of milk and will serve as a useful guide for farmers to adopt actions to mitigate the impact within the barns for the sustainability of livestock.
The Mediterranean diet biodiversity impact on metabolic and oxidative stress parameters in type 2 diabetes
Authors: RABHI Hasnia , GUERMOUCHE Baya , MERZOUK Hafida , MERZOUK Sid Ahmed
Published: July 2022

The aim of this study is to show the relationship between the adherence score to the Midetaraneen diet and the effects of metformin and insulin on metabolic disorders and oxydatif stress markers in Algerian men with T2D, in order to recommend the best treatment, which can minimize diabetes complications and demonstrate the value of adapting a Mediterranean diet in the management of T2D. Patients and Methods: We made this study on 120 men recruited from Sabra and 120 men recruited from Maghnia, Tlemcen (Algeria). Each group is divided into four groups (30 healthy control, 30 T2D without treatment, 30 T2D with metformin, and 30 T2D with insulin). A 14-item dietary questionnaire was applied to each individual to define adherence to the Mediterranean diet. Blood samples are collected for the determination of biochemical parameters (glucose, triglycerides, and cholesterol, high and low-density lipoprotein cholesterol) and oxidative markers (superoxide anion, nitric oxide, malondialdehyde, carbonyl proteins, oxygen radical absorbance capacity, vitamin C, catalase, glutathione). Our results show that type 2 diabetics from Maghnia have a higher adherence score to the Midetaranean diet compared to those from Sabra. This difference is related to the dietary and cultural diversity of each region. Moreover, Our results show that insulin reduces more lipid parameters than metformin, moreover, the oxidant/antioxidant status became normal in patients treated with metformin especially in Maghnia patients compared to Sabra diabetics. Conclusion: Insulin treatment is more effective in improving the lipid profile than metformin treatment. In addition, the combination of metformin, which reverses the redox changes associated with diabetes, and insulin, which improves all lipid profiles, should be prescribed in patients with type 2 diabetes in diabetics with high oxidative stress and hypertriglyceridemia. Moreover, the adaptation of a Mediterranean diet in Maghnia men has provided good control of type 2 diabetes.
From Place to Plate: Three Historical Etudes of Astrakhan. Etude #1
Authors: Yakushenkov Serguey
Published: July 2022

Various distant outskirts of Russia very often followed a specific path in their development, in no way resembling the culture of the Central Russia. One of such areas, where special cultural and natural environments existed, was the southern province located in the Delta of the Volga River – the Astrakhan province. Early in the Middle Ages this territory became a part of highly developed and powerful states – the Khazar Khaganate, the Golden Horde, and the Astrakhan Khanate were situated here. It was during this period that the main alimentary complex of the region was formed, which was a combination of the three main household types: cattle-breeding, fishing, and agriculture. This complex has survived to a large extent until the present day. The annexation of the Astrakhan Khanate by Russia in 1556 did little to change this configuration. The native inhabitants of these regions returned to their usual occupation, while the newly arrived peoples followed the same industries that had been familiar to them in their former homeland: gardening, fishing, or cattle breeding. The multinational character of the region's population led to a flexible system of economic relations and complementarity. As a result, there was an active cultural interchange between all the peoples of the region, which also influenced the alimentary landscape (foodscape).

The history of this foodscape can be divided into three major periods, which differ from each other in the specifics of their character. They are largely dependent on socio-political changes in Russia as a whole, which also stimulated serious cultural and social shifts in the region. This article is devoted mainly to the analysis of the formation of the first period of the alimentary landscape in the region. It lasted from the accession of the Astrakhan khanate to the First World War and the October Revolution of 1917.
Review of a Recipe Book by Jiang Dezhi “Tea for Women: a Path to Health with Herbs and Flowers”
Authors: Lixia Zhou
Published: July 2022

This work reviews a recipe book by Jiang Dezhi and other authors “Tea for women: a path to health with herbs and flowers”. Beijing: The Publishing house for Chemistry Industry. Volume: 180 pages. Illustrations: 90 by Wang Jianqiang. Date of publication: July, 2011. ISBN: 978-7122116307. Soft cover. Language: Chinese.1
SISTEM INFORMASI MANAJEMEN ASET ONLINE DENGAN PENELUSURAN DATA MENGGUNAKAN KONSEP STRING MATCHING
Authors: Putri Nadya Andhika , Hartanto Subhan
Published: July 2022

ABSTRAK Penelitian ini bertujuan untuk mengelola invetarisasi barang bersejarah yang ada di pusat informasi Geopark Kaldera Toba dengan menggunakan sistem infromasi manajemen aset. Metode yang digunakan dalam penelitian ini adalah string matching atau yang biasa disebut dengan algoritma pencocokan string yaitu algoritma untuk melakukan pencarian semua semua kemunculan string pendek dan panjang, string pendek yang biasa disebut dengan pattern sedangkan string yang panjang disebut teks.Sistem informasi ini dirancanng guna untuk menyediakan fungsionalitas pengelolaan informasi aset barang bersejarah yang meliputi registrasi aset, penempatan aset, pemindahan aset, penghitungan aset, penilaian aset, pencatatan maintanance, penghapusan aset, pelacakan aset dan pembuatan laporan. Kata Kunci:Sistem Informasi, manajemen aset, string matching
PENDAMPINGAN BELAJAR ANAK SELAMA PANDEMI COVID-19
Authors: Nugroho Andhi Dwi , Gemilang Adria Vitalya , Astuti Triana Wiji , Widyawati Ani , Fiani Ani
Published: July 2022

Adanya pandemi Covid-19 membuat pemerintah Indonesia menetapkan kebijakan untuk belajar dari rumah melalui sistem daring. Hal ini mengakibatkan kesulitan belajar bagi siswa. Motivasi belajar siswa mengalami penurunan sebab tak memadainya bimbingan dan arahan orang tua ketika menjalani pembelajaran di rumah. Dengan demikian, diperlukan sebuah kegiatan pendampingan pembelajaran di rumah guna membantu membimbing serta mengajar anak-anak jika mengalami kesukaran pada pembelajaran dirumah. Kegiatan pengabdian masyarakat dilaksanakan di Desa Singosaren, Kecamatan Banguntapan, Kabupaten Bantul, Yogyakarta berupa pendampingan bimbingan belajar di rumah bagi siswa sekolah dasar. Kegiatan ini diselenggarakan untuk siswa PAUD dan SD yang berjumlah 10 -12 siswa. Kegiatan yang dilaksanakan selama masa pandemi ini terdiri atas tiga tahapan yaitu, tahapan persiapan, tahapan pelaksanaan dan evaluasi. Hasilnya, siswa antusias dalam proses pendampingan belajar, hasil belajar siswa meningkat, dan semua tugas dikerjakan dengan baik. Dengan adanya pendampingan belajar ini bermanfaat membantu siswa yang kesulitan belajar secara daring di masa pandemi Covid-19.
PENYULUHAN PENGELOLAAN LIMBAH MEDIS BAGI TENAGA KESEHATAN DI PUSKESMAS KABUPATEN MAMUJU
Authors: Ashari Agus Erwin , Askur Askur
Published: July 2022

Pengelolaan limbah medis di puskesmas belum dilakukan secara baik sesuai ketentuan, berdampak terhadap gangguan kesehatan masyarakat dan lingkungan. Tujuan kegiatan pengabdian masyarakat adalah memberikan penyuluhan tentang pengelolaan limbah medis di fasilitas pelayanan kesehatan sebagai upaya peningkatan pengetahuan tenaga kesehatan. Kegiatan ini ikuti sebanyak 36 orang tenaga kesehatan yang ada di puskesmas Binanga dan Puskesmas Tampa Padang yang dilaksanakan masing-masing selama 1 hari. Penyuluhan dilakukan dengan metode ceramah, diskusi, sebelum dan setelah penyuluhan dilakukan pengukuran pengetahuan peserta. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan tenaga kesehatan tentang pengelolaan limbah medis di fasilitas pelayanan kesehatan sebesar 8,53. Berdasarkan hasil evaluasi kegiatan bahwa penyuluhan dengan metode cermah dan diskusi dapat meningkatkan pengetahuan tentang pengelolaan limbah medis di puskesmas.
PENDAMPINGAN PENGELOLAAN OPERASIONAL BISNIS DAN PEMASARAN TOKO KELONTONG DI BANGUNJIWO KASIHAN YOGYAKARTA
Authors: Gunawan Barbara
Published: July 2022

Tujuan dari program pengabdian ini adalah untuk membantu meningkatkan nilai ekonomi masyarakat dari Mitra yaitu Toko Bu Sri dan Kios Maheswari. Permasalahan Mitra (Warung Bu Sri dan Kios Maheswari) adalah semakin menjamurnya minimarket modern yang secara layout dan pelayanan tentu lebih baik daripada toko kelontong yang dikelola secara konvensional, seperti pemilik tidak membuat catatan persediaan barang, pemilik tidak membuat pembukuan, dan tidak melakukan promosi sebagaimana minimarket modern. Metode yang digunakan untuk memecahkan permasalahan tersebut adalah: 1) Focus Discussion Group dan pendampingan cara merapikan layout toko dan warung, 2) Pelatihan dan pendampingan tentang pelayanan kepada konsumen, luarannya berupa standar operasional prosedur pelayanan toko; 3) Pelatihan dan pendampingan pembuatan catatan persediaan barang 4) Pelatihan dan pendampingan pemasaran produk secara online, 5) Pengadaan mesin kasir, alat saji makanan, banner, dan lain-lain. Hasil dari kegiatan adalah: 1) Layout toko yang lebih rapi dan bersih, tersedia mesin kasir yang memudahkan toko dalam membuat faktur penjualan, 2) Pelayan memahami tentang pelayanan prima kepada pelanggan; 3) Tersedia katalog WhatsApp; 4) Warung Mie Ayam terdaftar di aplikasi Gofood, dan 5) Terselenggara pelatihan pencatatan. Setelah kegiatan pengabdian komentar pelanggan bahwa warung lebih bersih dan rapi sehingga omset warung mie ayam meningkat begitu juga dengan warung kelontong
PELATIHAN PENERAPAN CARA BUDIDAYA IKAN YANG BAIK (CBIB) RAMAH LINGKUNGAN DI SMU KECAMATAN TAEBENU
Authors: Surbakti Joi Alfreddi , Kamlasi Yusuf , Tasik Wahyuni Fanggi
Published: July 2022

Penerapan jiwa wirausaha sangat penting guna mendukung generasi muda untuk menjadi agen perubahan. Salah satu cara untuk memperkenalkan semangat berwirausaha adalah dengan memperkenalkan bidang perikanan.Untuk menumbuhkan jiwa yang mau berwirausaha bagisiswa Sekolah Menengah Umum (SMU)maka dilakukan pengenalan bagaimana Cara Budidaya Ikan yang Baik (CBIB) kepada para siswa yang berada di SMU Taebenu, Nusa Tenggara Timur. Pada kegiatan pengabdian ini siswa diajarkan dan langsung mempraktikan bagaimana cara budidaya ikan yang baik. Kegiatan ini antara lain membuat kolam, memelihara ikan dan proses pemanenan serta pemasaran ikan lele hingga ke konsumen. Pada kegiatan ini siswa sangat berperan aktif dalam setiap pelaksanaan kegiatan. Siswa membuat kolam, memilih benih ikan yang baik dan memelihara serta melakukan pemasaran ikan. Dari hasil yang dicapai pada kegiatan ini siswa menumbhkan jiwa wirausaha dan memiliki keinganan kuat untuk mengembangkannya.
MEMBANGUN JIWA WIRAUSAHA SANTRI MELALUI PELATIHAN PEMBUATAN GANTUNGAN POT BUNGA DANWORKSHOP KEWIRAUSAHAAN
Authors: Zain Efendi , Simon Zainal Zawir , Hukama La Diadhan , Zulihar Zulihar
Published: July 2022

Wirausaha identik dengan kemandirian, berpikir kreatif dan bertindak inovatif. Kemandirian dalam berusaha memberikan kesempatan kepada usahawan dalam memutuskan tujuan serta bentuk dan usaha tepat untuk dijalankan. Sejatinya jiwa wirausaha, telah tertanam dalam diri santri karena pendidikan di pondok pesantren mengedepankan kemandirian, kerja keras, disiplin dan kejujuran. Kegiatan ini bertujuan untuk meningkatkan kemampuan, keterampilan dan pengetahuan serta menumbuhkan jiwa wirausaha santri Pondok Pesantren Modern Daarul Uluum I Kota Bogor melalui pelatihan membuat kerajinan gantungan pot bunga dan workshop kewirausahaan. Hasil pelatihan menunjukkan bahwa telah terjadi peningkatan keterampilan, pengetahuan dan pemahaman santri tentang wirausaha. Hal ini dibuktikan berdasarkan hasil pengamatan ketika kegiatan berlangsung, para santri mampu membuat kerajinan gantungan pot bunga dan sangat antusias ketika mengikuti workshop kewirausahaan. Disamping itu, selama kegiatan berlangsung dari hari pertama sampai hari ketiga, sekitar 90% peserta mengikuti kegiatan sampai selesai
PELATIHAN PEMANFAATAN BARANG BEKAS SEBAGAI SARANA KREATIVITAS ANAK-ANAK DI PANTI ASUHAN USWATUN HASANAH SAMARINDA
Authors: Yatnikasari Santi , Pitoyo Pitoyo , Siswa Taghfirul Azhima Yoga
Published: July 2022

Panti asuhan berupaya dalam memberikan dukungan mental, fisik, dan sosial kepada anak asuh sebagai bentuk pelayanan kesejahteraan sosial untuk perkembangan kepribadiannya dengan bimbingan agama, pendidikan, sosial, dan lingkungan. Tujuan dari kegiatan pengabdian ini adalah: 1) memberikan pengetahuan kepada anak asuh agar dapat memanfaatkan barang dan bahan bekas di lingkungannya, 2) memberikan pelatihan kepada anak asuh untuk membuat kreasi pemanfaatan barang bekas, 3) memberikan pengetahuan bahwa dengan produk kreasi yang memanfaatkan barang bekas dapat mengembangkan kreativitas anak sehingga dapat bersaing dan berjiwa wirausaha yang akan membentuk pribadi tangguh dan mandiri. Kegiatan pengabdian masyarakat di Panti Asuhan Uswatun Hasanah diawali dengan tahap persiapan, selanjutnya tahap pelaksanaan kegiatan antara lain sosialisasi kegiatan, penyampaian materi dan pelatihan kreasi. Kreasi pot bunga sebagai pemanfaatan barang dan bahan bekas dibuat dengan melakukan pencampuran air dan semen sehingga berbentuk pasta. Peserta yang mengikuti kegiatan berjumlah 25 orang. Hasil dari kegiatan pelatihan, anak asuh memperoleh pengalaman dan pengetahuan yang baru dengan membuat 10 pot bunga yang dirancang menjadi produk kreatif bernilai estetika dan ekonomis serta menumbuhkan jiwa wirausaha. Berdasarkan aspek penilaian kreativitas dapat diketahui persentase kelompok yang mendapat nilai sangat baik adalah 30% dan nilai baik adalah 70% dari 10 kelompok yang ada, dengan nilai rata-rata adalah 77,6%, menunjukan bahwa peserta pelatihan pembuatan pot dengan memanfaatkan barang bekas mampu mengembangkan kreativitas dengan baik. Dengan kepedulian anak asuh terhadap kebersihan lingkungannya, maka dampak negatif dari pencemaran lingkungan dapat diminimalisir.