bluuebunny/crossref_metadata_2025 huggingface dataset:
Correlation of biological macrorhythms with exacerbations of lumbar osteochondrosis and acute disorders of cerebral circulation
Authors: Yakhin F. A. , Efimov P. A. , Yakhina F. F.
Published: April 2022

About 150 biorhythms are known, having a periodicity from one second to several years. Among them, the most studied are circadian (diurnal), probably related to the influence of the Earth's rotation [8, 9]. Recently, other macrorhythms have attracted the attention of researchers: physical, emotional and intellectual, the so-called Fliss biorhythms, also known under the name of the hypothesis of "critical days".
Detection and treatment of pollinosis in industrial workers
Authors: Sagatova G. A.
Published: April 2022

According to the frequency and prevalence of pollinosis, they occupy a leading place among allergic diseases. Regional features of the region and the prevailing type of vegetation significantly affect the etiology, pathogenesis and clinic of pollinosis. The most common allergen in central Russia is grass pollen, in the Krasnodar Territory ragweed pollen, in Kazakhstan - hemp pollen and 5 types of wormwood, in Uzbekistan cotton and walnut pollen. Although the etiological agent is plant pollen, dustiness, air pollution and, in general, urbanization play a major predisposing role in the occurrence of the disease.
A case of idiopathic pulmonary hemosiderosis with severe heart damage
Authors: Shcherbatenko L. A. , Andreev V. M.
Published: April 2022

Idiopathic pulmonary hemosiderosis is a rare disease of unclear etiology. .In most cases, it occurs in childhood, is characterized by repeated hemorrhages in the lung tissue and hemoptysis, iron deficiency anemia develops in the future. This disease often leads to death from massive pulmonary hemorrhage, sometimes from a pulmonary heart.
On the role of genetic determinacy in the pathogenesis of multiple sclerosis
Authors: Khondkarian O. A. , Zavalishin I. A. , Tananov A. T. , Nevsky O. M.
Published: April 2022

The objective of this study was to study the antigens and haplotypes of the histocompatibility complex HLA in patients with multiple sclerosis and their relatives.
Childbirth with congenital heart disease with a complex form of violation of intraventricular conduction
Authors: Latypov A. G. , Mingaleeva L. M. , Akperova F. F. , Sanzyapov P. N.
Published: April 2022

Blockades of two and even more three branches of the Gis - Purkinje system are serious violations of intraventricular conduction of the heart. They are dangerous by the unexpected and rapid transformation of their incomplete forms into a complete transverse blockade of the heart with all the consequences that follow from this, of which the most severe is the stoppage of blood flow.
A. Y. Ratner. Disorders of cerebral circulation in children. Publishing house of Kazan University, 1983, 143 p.
Authors: Dubenko E. G.
Published: April 2022

The publication of A. Y. Ratner's monograph "Disorders of cerebral circulation in children" is significant by the fact that there were no such monographic publications in the domestic literature. The book consists of an introduction and eight chapters.
All-Union Symposium "Experimental-theoretical and clinical aspects of the method of transosseous osteosynthesis" (Kurgan, September 20-22, 1983)
Authors: Sergeev V. M.
Published: April 2022

The symposium was attended by about 500 specialists, 72 of them from foreign countries. The symposium was opened by Deputy Minister of Health of the USSR A. G. Safonov. Then the Hero of Socialist Labor, Lenin Prize laureate Prof. G. A. Ilizarov made a report "The importance of a complex of optimal mechanical and biological factors in the regenerative process in transosseous osteosynthesis." The speaker noted that such traditional methods of treatment as plaster cast, skeletal traction and metal internal fixators, still used in traumatology and orthopedics, do not ensure the immobility of bone fragments. In addition, internal fixators damage blood vessels, periosteum, endost and bone marrow; their removal is quite difficult and traumatic. Only with stable fixation of precisely prepared fragments, careful attitude to osteogenic tissues, good blood supply to them, preservation of the musculoskeletal function of the limb, optimal mechanical and biological conditions are created for accelerated formation of bone fusion and functional recovery. These conditions are achievable with the use of strong fixation of bone fragments in the Ilizarov apparatus, with closed osteoclasia and distraction in automatic mode up to 1.9 mm per day. Transosseous osteosynthesis allows bloodless treatment of all closed fractures; to compensate for large defects of soft tissues, blood vessels, nerves of bone without transplantation and in one stage even in conditions of infection; to thicken the bone and its fragments. Ilizarov's method makes it possible to eliminate the false joint and shortening of the limb bloodlessly and in one stage; to delay the growth or lengthen the limbs; to eliminate deformities of long tubular bones and joint contractures. Transosseous osteosynthesis is used for the purpose of bloodless prolonging arthrodesis of large joints; for compaction of bone tissue; excitation of osteogenesis and its management to fill bone cysts and foci in Ollier's disease. In addition, it can be used to lengthen a limb and at the same time eliminate its deformation; fix joints with arthroplasty on hinges, cure syndactyly and replace the skin without transplantation; lengthen and change the axis of the spine; simulate a limb, stump, finger; expand the pelvis, increase the vessel. The method can be used on an outpatient basis.
Hemodynamic disorders as a risk factor for the development and course of the glaucomatous process
Authors: Chamitova G. X. , Musin M. F.
Published: April 2022

The prognosis for primary glaucoma depends on the ability of the optic disc to withstand the effects of increased intraocular pressure. Among the reasons for this quality, the intensity of blood supply to the tissues of the disc and the retralaminar region plays a significant role [5]. Cervical osteochondrosis and atherosclerosis affect the state of the visual organs. At the same time, visual function disorders are mainly explained by a disorder of hemodynamics in the vertebrobasilar system [1, 2, 6].
Muscle lesions in hypercorticism
Authors: Agafonov B. V. , Kalinin A. P. , Mozherenkov V. P.
Published: April 2022

In recent years, there have been many reports in the literature about muscle lesions caused by hypercorticism of both endogenous and exogenous origin. For the first time, muscular disorders in patients with basophilic pituitary adenoma were described in 1932 [15]. Further observations [1a, b, 4, 6, 7, 19, 25] It allowed us to characterize the features of muscular pathology in Itsenko-Cushing's disease and Cushing's syndrome, expressed by muscle weakness mainly of the proximal parts of the legs and pelvic girdle and to a lesser extent of the proximal parts of the arms and shoulder girdle. The muscles of the shins, interosseous muscles of the hands and feet are less often affected. Muscle atrophy does not always reach a significant degree, moreover, it is often masked by excessive fat deposition. Such patients have difficulty climbing stairs, getting out of bed, lifting their arms above the horizontal level. Muscle weakness is combined with a decrease in tendon reflexes until they disappear with severe atrophy. The muscles of the anterior abdominal wall are often affected, which can partially explain the sagging of the abdomen in patients [5].
Chemotherapy in phthisiology and pulmonology
Authors: Smirnov G. A.
Published: April 2022

The therapeutic effect of antibiotics and chemotherapy drugs depends on the level of their active concentration formed in the blood and tissues of patients. However, in the process of evolution, living organisms have developed the ability to maintain the constancy of their internal environment. Therefore, all substances, including medicines that enter the body and are by nature alien to it, undergo neutralization processes and lose their specific properties and pharmacological activity, that is, they are inactivated.
The use of trental in the complex treatment of patients with chronic pyelonephritis
Authors: Neymark A. I.
Published: April 2022

Studies by a number of authors have revealed significant changes in microcirculation and renal hemodynamics in patients with pyelonephritis. Slowing of capillary blood flow, vasospasm, aggregation of erythrocytes and a decrease in effective renal blood flow were found. These disorders are significantly aggravated after kidney surgery and require corrective treatment. Therefore, along with antibiotics, cardiac glycosides, antispasmodics, antihistamines, we prescribed trental (pentoxifylline), which dilates blood vessels, improves the rheological properties of blood, reduces its viscosity and increases the elasticity of red blood cells.
Treatment of patients with uterine fibroids with prolapse and prolapse of the walls of the vagina and uterus
Authors: Vasilevskaya L. N. , Bagaev V. M. , Firichenko V. I.
Published: April 2022

The choice of tactics for the treatment of patients with uterine fibroids in combination with the prolapse and prolapse of the walls of the vagina and uterus is currently one of the most difficult problems.
The incidence of dental caries in children who received glucocorticoids for rheumatism
Authors: Terekhova L. M.
Published: April 2022

The dental condition of 201 children aged 7 to 14 years suffering from rheumatism was examined, of which 101 patients were treated with glucocorticoids. 731 healthy children of the same age were examined for control.
Differential diagnosis of osteoblastoclastoma of long tubular bones
Authors: Volodina G. I. , Laryukova E. K. , Gilyazutdinov I. A.
Published: April 2022

The issues of X-ray diagnostics of osteoblastoclastomas have been repeatedly discussed in the literature. The most characteristic radiological symptoms of this one of the most frequent bone tumors are described in detail [i2, 4]. Our long-term observations show that radiologists experience differential diagnostic difficulties in interpreting radiographs of patients with osteoblastoclastoma. The conclusion about the presence of osteoblastoclastoma is often erroneous. This prompted us to focus on the issues of differential diagnosis of osteoblastoclastomas.
About the content of diastase in urine after gastric resection
Authors: Nikolaev G. M.
Published: April 2022

As you know, after resection of the stomach for peptic ulcer disease, many surgeons described severe complications in the form of acute inflammation, damage and necrosis of the pancreas. N. I. Leporsky reported data from different authors about 145 cases of damage to the pancreas during various operations. S. V. Lobachev, based on materials from the Institute. Sklifosovsky for 6 years, indicates that after operations in the abdominal cavity there were 166 cases of trauma to the pancreas, which occurred due to the invasion of the gland by a tumor or with penetrating ulcers. Moreover, 33 patients (22%) developed acute pancreatitis, 19 of them died. A. T. Rozhkov on 393 gastric resections in 18 patients had damage to the pancreas; of these, 9 developed fatal necrosis. G. S. Rozanov for one year observed two patients with acute pancreatitis, which arose in connection with resection of the stomach. Unfortunately, he does not write how many operations these complications account for. I. V. Starkov analyzed the case histories of 100 patients after gastric resection for cancer or ulcers; of these, in 7 the immediate cause of death was necrosis of the pancreas. Another 8 patients had partial necrosis of the pancreas, but the author considers other complications to be the cause of death. Prof. B. S. Rozanov writes that during operations on the stomach for penetrating ulcers, the pancreas is not so rarely injured with subsequent purulent fusion or necrosis.
Surgical treatment of severe forms of thyrotoxic goiter using neuro-vegetative drugs
Authors: Kravchenko P. V. , Rudova S. I.
Published: April 2022

Thyrotoxicosis, the most severe form of thyroid disease, is regarded as a disease of the whole organism with severe functional disorders of the cardiovascular and nervous systems. Preparation of patients with thyrotoxic goiter for surgery, the choice of the method of pain relief and the fight against postoperative thyrotoxic crisis, cardiovascular failure and shock are of decisive importance in the immediate outcome of the operation.
Diabetes mellitus and pregnancy
Authors: Rybkina N. F.
Published: April 2022

Since there are patients with diabetes mellitus among pregnant women, the study of the peculiarities of the course of this disease and, in turn, the influence of diabetes on the course of pregnancy and childbirth is of practical interest. Carbohydrate metabolism during pregnancy is distinguished by its lability. G. G. Genter points out that in almost 10% of pregnant women, sugar is excreted in the urine from time to time throughout pregnancy. According to our data, glucosuria is rare in pregnant women. In maternity hospital No. 1 of Gorky, out of 47357 women in labor, we observed glucosuria in only two, and in the regional hospital. N. A. Semashko - at one.
Some biochemical indicators of the composition of the amniotic fluid with polyhydramnios
Authors: Sozansky A. M.
Published: April 2022

The biochemical composition of amniotic fluid during pregnancy complicated by polyhydramnios has not been essentially studied, although it is of interest for elucidating the mechanisms of polyhydramnios, prevention and treatment. We have studied the content of sugar, chlorides, urea, residual nitrogen and total protein in the amniotic fluid in 11 pregnant women suffering from polyhydramnios. The diagnosis of polyhydramnios in them was made on the basis of a clinical study and then confirmed by measuring the amount of amniotic fluid obtained during childbirth.
On the casuistry of hemochromatosis (bronze diabetes)
Authors: Grabenko I. K. , Kastanayan E. S. , Levchenko A. L.
Published: April 2022

The essence of the disease mainly consists in a violation of iron metabolism with increased deposition of it in a number of organs and, mainly, in the liver, mainly in the form of hemosiderin. The term "hemochromatosis" was introduced by Recklinghausen (1889) and reflects one of the characteristic symptoms of the disease an abnormal coloration of the skin (melasma) and organs, due to the deposition of pigments in them, according to the author of blood origin. With the help of labeled iron, it was found that increased deposition of iron in the liver and in other organs during hemochromatosis is associated, in contrast to hemosiderosis (with hemolytic jaundice, pernicious anemia), not with increased blood breakdown, but with an increase in the absorption of iron from the digestive tract.
Electrocardiographic changes in hypertension in young people
Authors: Shukhtina A. M.
Published: April 2022

Of the 246 dispensaries from 16 to 35 years old, there were 119 women, 127 men. Stage I was found in 85.3% and stage II in 14.7%. The duration of the disease up to 3 years was in 8.6%, up to 8 years in 70.2% and more in 21.2%. Systolic pressure did not exceed 150 mm in 43.7%, it was above 150 mm in 56.3%. Diastolic pressure up to 90 mm was observed in 42.3%, above 90 mm - in 57.7%. Resting ECGs rarely showed disturbances in rhythm, conduction, changes in systolic readings, or in the position of the electrical axis of the heart.
Experience in the treatment of gynecological patients at the mud resort "Slavyansk"
Authors: Markov A. Ya.
Published: April 2022

We have investigated and developed case histories of 701 gynecological patients who were treated in 1954 in Slavyansk. Of these, 540 (group I) had various chronic inflammatory processes of the female genital organs and 161 (group II) had primary infertility, mainly due to inflammatory processes. Among patients of group I with a disease duration of up to two years, it was 14.5%; up to three years - 12.2%; under 5 years - 19% and over 5 years - 54.3%.
Psychotherapy in obstetric practice
Authors: Poplavsky A. K.
Published: April 2022

Psychotherapy was used by us in 52 patients: with "indomitable" vomiting - in 8, with other forms of early toxicosis - in 24 (of them in 8 with itching), threatening miscarriage - in 6, nipple hyperesthesia - in 12 and in 2 with disorder urination in the postpartum period. Psychotherapy was used in the form of suggestion in hypnotic sleep and hypnotic sleep as such. As one of the techniques, easily implemented in an obstetric clinic, they used the transformation of natural sleep into hypnotic sleep. We have repeatedly succeeded in converting natural sleep into hypnotic sleep in the first session. In some cases, we performed the first session using conventional sedation techniques, and during the second session, we proceeded to transform sleep into hypnosis.
Surgical treatment and methods of pain relief in patients with thyrotoxicosis
Authors: Kaluzhskyh V. N.
Published: April 2022

From the time of N. I. Pirogov to the present day, in the treatment of patients with severe forms of thyrotoxicosis, who have unsuccessfully experienced conservative therapy, the method of choice is surgery. In our clinic for 23 years more than 850 patients with simple and thyrotoxic goiter have been operated on. Of these, 467 underwent surgery for thyrotoxicosis. There were 12.6 times more women than men. Most of the patients were middle-aged. In recent years, operations have been performed much more often in patients with thyrotoxicosis, much less often in patients with simple goiter.
On the effectiveness of papaverine, erinitis and euphyllin in patients with angina pectoris
Authors: Volkov V. S. , Bratolyubov V. P.
Published: April 2022

As a result of treatment of 90 free angina pectoris with papaverine, erinitis and euphyllin, most of them experienced significant subjective improvement and increased exercise tolerance. The therapeutic effect of the use of the studied antianginal drugs was largely due to a decrease in blood pressure at rest, as well as in heart rate and blood pressure during exercise. Among the indicated coronary active agents, the best results were provided by aminophylline, the second most effective was erinitis, and the third was papaverine.
Resection of the stomach with congenital anomalies in the location of the intestine
Authors: Arkhipov E. P. , Zabirov K. S. , Kuznetsov G. M.
Published: April 2022

Since congenital anomalies in the location of the intestines are rare, and operating with them puts the surgeon in unusual conditions, we consider it necessary to report the case we encountered. Patient M., 33 years old, was admitted on 28 / III-59, about constant, worsening at night pain in the epigastric region with irradiation to the lower back. The pain was often accompanied by nausea, vomiting, and heartburn. A patient with low nutrition, the skin and visible mucous membranes are pale, the turgor is low. Tongue coated with white bloom. On palpation, there is a protective muscle tension and soreness in the epigastric region. No changes were noted on the part of other organs and systems.
The problem of hormone therapy at the All-Russian conference of physicians
Authors: Anisimov V. E.
Published: April 2022

The conference was devoted to one of the urgent problems of modern medicine - the use of corticosteroid hormones in the treatment of certain diseases of internal organs. Prof. I. A. Yudaev (Moscow) emphasized that these hormones have a versatile effect on the human body and noted that when they are used, ammonia accumulates in the body. The introduction of glutamic acid leads to the elimination of this phenomenon and thus allows the continued treatment with hormones. Corticosteroids are tissue specific.
Scientific conference of the Kazan State Pedagogical University named after V.I.Lenin
Authors: Vylegzhanin N. I.
Published: April 2022

The conference took place on April 23 and 25, 1960 to commemorate the 90th anniversary of the birth of V. I. Lenin, the 40th anniversary of the TASSR and the 40th anniversary of the founding of the Institute. The first reports were devoted to these significant dates. The special part of the conference was presented by 27 reports. In 6 of them, the result of many years of work of a number of main departments (pediatrics, surgery and oncology, obstetrics and gynecology, roentgenogy and radiology, etc.) was given.
Some questions of the epidemiology of chronic fibrocavernous pulmonary tuberculosis
Authors: Sherman A. Sh.
Published: April 2022

We examined 150 foci, in which lived, in addition to patients with fibrocavernous pulmonary tuberculosis, 353 people who were in family contact with them. 22 had a tuberculous process in the lungs. In these patients, it was not possible to establish a connection between diseases and contact with a bacillus-releasing agent, or this connection was very doubtful, and 331 people. were healthy and during the initial clinical and radiological examination in the dispensary, no pathological changes in the lungs were found.
Two cases of spontaneous subcutaneous emphysema during childbirth
Authors: Plastunov A. B.
Published: April 2022

Woman in labor B., 21 years old, primiparous, was admitted to the clinic with a post-term pregnancy at 42 weeks, with symptoms of toxicosis in the 2nd half of pregnancy, with moderately pronounced edema on the lower extremities. At the beginning of pregnancy, there were nausea and vomiting, from the 5th month - swelling in the legs. Previously suffered from rheumatic heart disease with mitral valve lesions; the process is now in the stage of compensation. The physique is correct. Borders of the heart are normal, the tones are muffled, systolic murmur at the apex.
Immediate and long-term results of cervical cancer treatment
Authors: Slepov M. I. , Krylova Z. T. , Larionova L. M.
Published: April 2022

An analysis of the results of treatment of 124 patients with stage I cervical cancer showed that with a depth of invasion of up to 3 mm, the volume of surgical intervention can be reduced to a simple extirpation of the uterus without risk to the patient's health and life.
Thromboelastography indices for certain kidney diseases
Authors: Sokratov N. V. , Bashkov G. V. , Klimkina T. I. , Ashirov R. S. , Bondar V. V.
Published: April 2022

Thromboelastogram (TEG) indices were studied in 89 patients. 26 of them had pyelonephritis, 6 had hemorrhagic fever with renal syndrome (HFRS), 26 had acute nephritis and 31 had a mixed form of chronic diffuse glomerulonephritis.
Nonparasitic liver cyst
Authors: Gantsev Sh. Kh.
Published: April 2022

The clinical picture of nonparasitic liver cysts is characterized by poor symptoms and depends primarily on the size of the cyst, its location and complications. Patients complain mainly of dull and bursting pains in the right hypochondrium, epigastrium, as well as a feeling of discomfort and enlargement of the liver and abdomen.
Detection of biliary dyskinesias in children with five-fraction duodenal intubation
Authors: Cherkasova N. A. , Bzhasso Z. Kh.
Published: April 2022

With continuous five-fraction duodenal intubation, the volume of individual portions of bile, the time and rate of their release in one minute are taken into account. There were 213 children under our supervision 127 girls and 86 boys aged 5 to 14 years. All children were admitted to the hospital for pain and abdominal pain, more often in the right hypochondrium. Half of the children complained of nausea, vomiting, and intestinal dysfunction. Palpation of the abdomen revealed pain in the right hypochondrium, often revealed tension in the abdominal muscles in the choledocho-duodenal zone. In 32 children, the liver was palpated 1.5-2 cm below the costal arch.
Physiological and hygienic assessment of the working conditions of foremen of machine-building enterprises
Authors: Krasnoshchekova V. N.
Published: April 2022

A comprehensive physiological and hygienic examination of the working conditions of foremen of machine-building enterprises was carried out. The duties of the foremen include solving a number of organizational tasks, the implementation of which is associated with being directly in the shop for 60% of the working time. Physiological studies have established a decrease in the work capacity of foremen by the end of the working day due to an increase in fatigue.
Is the Long-Term Probability of the Occurrence of Large Earthquakes along the Nankai Trough Inflated?—Scientific Review
Authors: Hashimoto Manabu
Published: April 2022

The Earthquake Research Committee (ERC), the Headquarters for Earthquake Research Promotion, Japan, issued a new report on long-term evaluation of the occurrence of large earthquakes along the Nankai trough, southwestern Japan, in 2013, which was made along the line of the revision of national earthquake counter measures according to the 2011 Great Eastern Japan Earthquake Disaster. The central issue was the 30-yr probability, but the method to estimate probability was not changed from the previous one issued in 2001 based on the time-predictable model, which led to a 60%–70% chance of M ≥ 8 event during the coming 30 yr. However, there are several drawbacks in this evaluation such as neglect of errors in uplift data, inconsistency between uplift rate and geodetic and geomorphological data, mechanical interpretation of time-predictable model, and contradiction between the assumptions in Brownian passage time model and time-predictable model. Because ERC calculates probability with average recurrence intervals for other subduction and active fault zones, the same scheme should be adopted to the Nankai trough.
Surgical Treatment of Age-Related Cataracts: Milestones and Challenges. Literature Review
Authors: Bikbov М. М. , Isragilova G. Z. , Gilmanshin T. R.
Published: April 2022

Cataract (partial or complete violation of the transparency of the lens) is one of the main causes of low vision and reversible blindness in the world. It is a known fact that at present the only effective way to eliminate the clouding of the lens is its surgical treatment. About 18 million cataract-related surgical interventions are performed annually in the world. This literature review is devoted to studies examining important aspects of surgical treatment for age-related cataracts, such as the number and quality of operations performed on a population scale. The paper presents data on the impact of global trends, local territorial and social characteristics on the number of surgical interventions for cataracts. A review of key indicators of monitoring cataract surgery has been carried out, the main factors affecting the target indicators of the cataract surgery frequency on a regional scale (age structure of the population, normative indications for surgical treatment, threshold values for visual acuity indicating the need for surgical intervention, and the proportion of people in need in surgical treatment of cataracts). The main achievements and aspects of the modern technique of surgical treatment of cataracts are described, which can reduce the time of surgery, use more gentle surgery technology, significantly reduce the number of complications and achieve the highest functional results. This review also details the results of the largest epidemiological studies on the causes of low visual acuity after cataract surgery. Literature data on the prevalence of low visual acuity in different populations are reflected, its higher prevalence in countries where most of the operated cataracts were mature or complicated was revealed, the surgical technique of large incisions and a longer operation time prevailed. It was noted that low vision after cataract surgery is most often associated with the elderly patient, concomitant systemic and ocular pathology, surgical complications, inadequate intraocular correction.
Clinical Case of Echinococcosis of the Orbit. Modern Approaches to Diagnosis and Treatment
Authors: Gorbachev D. S. , Kulikov A. N. , Kozlov S. S. , Kolbin A. A. , Voronov A. V. , Kudryavtseva A. V. , Kovalevskaya I. S. , Yakovenko A. I. , Burnasheva M. A. , Haritonova N. N. , Zemlyanukhin N. V.
Published: April 2022

The article presents the epidemiology of echinococcosis in Russia, its strains, their pathogenicity for humans. The ways of spread and infection of the parasite, as well as the features of invasion into the human body, are indicated. The role of radiation methods for diagnosing echinococcosis using ultrasound, CT and MRI is described in detail. The reasons for the low appealability of patients with echinococcosis of the orbital organocomplex and the low efficiency of drug treatment are indicated. The importance of early surgical treatment for patients with lesions of the orbital organocomplex is emphasized. A clinical case of observation of a patient with primary multiple echinococcosis with damage to the orbital organocomplex, as well as the liver, lungs and spleen is presented. The patient complained of exophthalmos of the right eye to the clinic of ophthalmology of Professor V.V. Volkov Military Medical Academy of S.M. Kirov. An objective examination revealed signs of impaired position and mobility of the exophthalmos, impaired visual functions, electrical response of the retinal. In the fundus marked signs of swelling of the optic nerve. According sockets CT revealed the formation of cystic right orbit emanating from the medial rectus muscle remodeling medial orbital wall and a bottom; right-sided exophthalmos. According to MRI determined pattern of cystic formation, coming from the medial rectus muscles of the right eye. The cyst led to a violation of visual functions, there was a risk of rupture and dissemination of the parasite in the body. With this in mind, it was decided to remove it from the eye socket. During transnasal endoscopic intervention, the neoplasm was removed from the right orbit. The postoperative period was uneventful. Considering the rarity of echinococcus lesions of the orbital organocomplex on the territory of Russia, it is necessary to use an individual approach for surgical intervention in patients with this pathology. An interdisciplinary approach allows minimally traumatic removal of an echinococcal cyst from the orbit. It is noted that the duration of antiparasitic therapy should be determined in each case individually.
Treatment Results of Residual-Angles Operated Esotropia by the Method of Z-Shaped Marginal Myotomy
Authors: Gavrilyuk A. S. , Artamonova A. V. , Ivanova A. O. , Maksimov I. V. , Zubareva L. N.
Published: April 2022

Purpose. Analysis of the results of weakening of previously operated internal rectus muscle by the method of Z-shaped marginal myotomy.

Patients and methods. The study included 87 children with an initially large-angle of strabismus. Children age — from 2 to 14 years (average age — 9.09 ± 0.78 years). The initial strabismus angle was from 30° to 60° according to Girschberg (average angle — 45.7° ± 2.3°). All children underwent a staged surgical treatment — recession of the internal rectus muscle and resection of the external rectus muscle in both eyes. The residual deviation angle after two stages of surgical treatment ranged from 6° to 10° (on average up to 9.1° ± 0.75°) according to Girschberg. All patients underwent a Z-shaped marginal myotomy on the operated internal rectus muscle. The follow-up period after surgery ranged from 1 year to 5 years.

Results. A satisfactory anatomical result (orthotropy) was achieved in 91 % of cases (79 children), hypocorrection in 9 % of cases (8 children), hypercorrection — 0 %. In 8 patients with hypocorrection, after 6–8 months, the fourth stage of surgical treatment was performed with the method of Z-shaped marginal myotomy of the internal rectus muscle in the paired eye, after which orthotropy was achieved.

Conclusion. An analysis of the surgical treatment results of operated esotropia have showed that the method of Z-shaped marginal myotomy makes it possible to weaken the tone of the previously operated internal rectus muscle with minimal trauma. Using the method of Z-shaped marginal myotomy in the treatment of residual-angle strabismus, orthotropy is achieved while preserving the biomechanics of the oculomotor muscles — the internal rectus muscle remains in the plane of its functional action. At initially large-angle of strabismus, conducting a Z-shaped marginal myotomy of the internal rectus muscle after stepwise surgical interventions on the horizontal rectus muscles of both eyes can be recommended as a modern, reliable and effective method of surgical treatment of residual-angle of strabismus, which allows to achieve the planned functional and cosmetic result.
Avaliação formativa em contexto digital com tecnologias digitais interativas
Authors: Mignoni de Oliveira Raquel , Corrêa Ygor , Dias-Trindade Sara
Published: April 2022

Este artigo trata da avaliação formativa on-line em contexto digital com tecnologias digitais interativas no ensino remoto emergencial durante a pandemia de covid-19. O relato de experiência descreve aulas de Língua Portuguesa, a partir da Base Nacional Comum Curricular no ensino fundamental. As tecnologias digitais interativas elencadas tiveram caráter pedagógico e avaliativo para acompanhar, refletir, personalizar e avaliar os estudantes nas aulas on-line. O estudo evidenciou que a adoção de estratégias pedagógicas para autoavaliação, participação, desempenho e colaboração dos estudantes na disciplina constituiu elemento indispensável para a formação integral e curricular.
Clinical utility of the FilmArray blood culture identification 2 panel in identification of microorganisms and resistance markers from positive blood culture bottles
Authors: Shah Sweta , Davar Namita , Thakkar Pooja , Sawant Chandrakala , Jadhav Lavina
Published: April 2022

Bloodstream infections (BSIs) remain a leading cause of morbidity and mortality especially in intensive care units across the world and timely appropriate antimicrobial therapy is a corner stone in its treatment

(i) To compare the time difference to diagnose BSIs between FABCID2 and identification and sensitivity by automated systems (ii) To analyse the clinical utility of the FABCID2 panel in positive blood samples among ICU patients.

This was a prospective study done from July 2020 to August 2020 where consecutive thirty positive blood culture received from ICUs were processed for gram stain, culture and antimicrobial susceptibility along with performing PCR with BioFire FilmArray Blood Culture Identification2 (FABCID2) Panel. Time line of positive blood culture from receipt to report generation at multiple points were captured along with impact of results in terms of changing antimicrobial therapy of the patients and outcome.

: A total of 38 microorganisms were identified from 30 patients. In 70% (21/30) of patients, the result of FABCID2 and growth in culture matched completely, in 23% (7/30) they matched partially and in 6% they did not match. The match between genotypic markers in the assay and phenotypic susceptibility was 100%. FABCID 2 results prompted clinicians to change the antimicrobials prescribed to 33% of total patients (escalation was done in 23.3% of patients and de-escalation was done in 10%.

Clinical utility of the FABCID2 Panel in Identification of microorganisms and resistance markers from Positive Blood Culture Bottles is significant which should be used in conjunction with conventional methods to impact patient outcome and antimicrobial stewardship program.
Molecular detection of dengue virus serotypes prevalent in central Kerala and its correlation with disease severity
Authors: R Rugma , Valsan Chithra , Sreekumar E , Sathiavathy KA
Published: April 2022

Dengue is the most important mosquito-borne viral disease in the world. In 2017, a concerning increase in dengue cases with high mortality was seen in India with Kerala topping the list. Changing pattern of circulating dengue virus serotype and co infection with multiple serotypes contribute to the increasing trend in severity and increased mortality of dengue fever. The present study focused to find the dengue serotypes prevalent in central Kerala and prevalence of co infection with multiple serotypes here with an attempt to correlate these with clinical severity of dengue

: This descriptive study was done in the Microbiology department of Jubilee Mission Medical College, Thrissur for a period of 18 months. Blood samples of clinically suspected dengue fever cases which were positive for NS1 antigen and having fever not more than 5 days were subjected to molecular methods to detect dengue virus RNA followed by multiplex RTPCR to find its serotype. Demographic features, clinical details and lab parameters were also collected from each patient.

A total of 108 samples positive for Dengue NS1 antigen were subjected to RT-PCR. Among them 61(56.5%) were positive by RT-PCR. All the 4 Dengue serotypes were found with DENV-2 with 30 cases (49.2%) being the predominant serotype followed by DENV-1 with 20 cases (32.8%), DENV-3 with 12 cases (19.6%) and DENV-4 with 2 cases (3.27%). Three cases (4.9%) of co infection with DENV-1,2, DENV-1, 4 and DENV-2,3 were also found. Two among the 108 patients (1.85%) died in the present study. Significant correlation between severity of dengue infection and serotypes could not be found due to very few severe cases encountered during the study.

: The dengue serotypes predominant in central Kerala is DENV-2. The prevalence of co infection with multiple serotypes is 4.9% which proves that this area has become hyper endemic to the disease, which increases the risk of emergence of more severe cases.
Assessment of stress distribution pattern in mandibular buccal shelf area during retraction with different angulation using buccal shelf screws — A 3d finite element study
Authors: Pillai Jishnu J , Yadav Ashish , Misra Vaibhav , Joshi Divya , Attri Sonal , Johnson Jithin
Published: April 2022

Orthodontics in its century of existence have had a lot of landmarks in its evolution, but very few can match the clinical impact made by micro-implants and the recently introduced infra-zygomatic crest & buccal shelf orthodontic bone screws. Micro-implants and extra-radicular BS have brought about a renaissance to the field of orthodontics with its concept of absolute anchorage in the past decade. It is an added armamentarium in the hands of an experienced clinician to overcome new clinical challenges and convert even borderline surgical cases to nonsurgical without, compromising with the results achieved. Aim It is a FEM study in which buccal shelf screws are inserted in buccal bone lateral to the distal root of the 2nd molar and 4 mm buccal to the CEJ with different retraction forces and various angulation to study stress pattern in MBS area. Material and Method CBCT 3D image of the study mandible is made and the image transfer to the software. A FEM is created using a dedicated software. Orthodontic buccal shelf screws which is made of titanium alloy (diameter, 2 mm; length, 12 mm; thread ridge height, 0.2 mm; thread pitch, 0.6 mm). Miniscrew implant insertion is designated at 30°, 40°, 60°, 70°, and 90° angulations, and at each angulation a horizontal load of 150, 200, and 250 g is applied. Results BSS when inserted in buccal bone 60-70 degree angulation showed the least stress pattern in mandibular buccal shelf area and 40 – 50 degree angulation showed maximal stress distribution pattern.
Comparison and correlation between mandibular morphology among diferent vertical growth patterns: A cephalometric study
Authors: Mahajan Roshni , Thukral Rakesh , Garg Ashish , Tripathi Amit , Singh Choudhary Amit
Published: April 2022

: In the field of Orthodontics and Dentofacial Orthopedics, in-depth knowledge of mandibular morphology and different types of growth pattern is essential to reach to ideal treatment for every patient.

To compare antegonial notch depth, symphysis morphology and ramus morphology among different growth patterns. 2) To correlate antegonial notch depth with other parameters of mandibular morphology.

: In this study, lateral cephalogram of total 90 patients were traced. The sample was divided into horizontal, average and vertical growth pattern based on Jarabak’s ratio. The antegonial notch depth, symphysis morphology (i.e. its height, depth, ratio and angle) and ramus morphology (its height and width) were evaluated and analysed statistically. The symphysis ratio is the ratio of symphysis height to symphysis width.

: This study revealed that antegonial notch depth, symphysis angle and ramus height shows statistically significant difference among different growth patterns. In vertical growth pattern, antegonial notch depth is positively correlated with symphysis height, symphysis depth, ramus height and ramus width whereas it is negatively correlated with symphysis ratio and symphysis angle and exactly opposite is true for horizontal growing individuals.

: This study concluded that there is correlation between mandibular morphology and growth pattern of an individual.
Prevalence of malocclusion in school going children of age 12-15 years in Telangana
Authors: Durga Prasad G. , Raja Sigamani K , Kumaran Kurichi , Yashaswini K.V. , Rohith Sai
Published: April 2022

Health is the functional or metabolic regulation of a living body. In humans, health is an individual capability to conform and adjust to the challenges like socially, mental or physically. Mouth is the window to health of our body. Most of the nutritional deficiencies, systemic diseases, infections etc are manifested first as oral conditions. Good oral health is very important for overall wellbeing of an individual. Malocclusion is a misalignment or incorrect relation between the teeth of the two dental arches when the jaws are closed. Malocclusion is the highest public health problem in the world because of its high prevalence. Worldwide data on prevalence of malocclusion has shown that malocclusion is more prevalent in whites than in blacks, then more in females than males and more in developed countries than in developing countries, less in rural population than urban population. A definite geographical and racial variation is seen in southern and northern parts of India. In India class I malocclusion is more prevalent than class II and class III malocclusions. A prior recognition of malocclusion not only aids in intercepting its severity but it also helps in addressing the aesthetics and functional problems.
Severe class II div 2 malocclusion with impacted canines- A case report
Authors: Kshetrapal Abhishek
Published: April 2022

Non surgical correction of severe deep bite malocclusion always poses a challengeespecially when it is associated with a Class II skeletal base. Here a case with severe Class II div 2 malocclusion (>200% deep bite) with impacted canines is presented which was successfully treated non-surgically.

Class II div 2 malocclusion, impacted canines, skeletal deep bite, gummy smile
Los espacios públicos en América Latina y el Caribe: guía práctica para su reactivación en la pospandemia
Authors: Patterson-Waterson James , Pozas Franco Inés , Vexler Caroline , Rodríguez Villafuerte Karina , Gómez Jiménez Alicia , Winter-Taylor Michaela , Molina Gabriela , Rodríguez José Daniel , Sáenz María Paula , Madera Arends Roberto , Richter Elías Alessandra
Published: April 2022

A lo largo de la pandemia del COVID-19, las ciudades han reconocido el importante rol que cumplen los espacios públicos para ayudar a las comunidades a superar los desafíos económicos y de salud más urgentes como consecuencia de los cierres. Los parques, plazas y calles se convirtieron en el principal escenario de entretenimiento, de desarrollo de actividades físicas, de mejora de la salud mental, y de reactivación económica. Lo que parece ser un dilema lleno de incertidumbre ha significado una oportunidad para los gobiernos locales, en la cual el espacio público está jugando un rol fundamental para reactivar las ciudades. Esta publicación busca apoyar a las autoridades locales de la región en la reactivación de los espacios públicos de una manera segura. El propósito de esta guía es contribuir a que las autoridades locales tomen decisiones más meditadas y holísticas, teniendo en cuenta las implicaciones a largo plazo asociadas a mejorar la calidad y el uso de los espacios públicos en sus ciudades. La publicación presenta conceptos, herramientas y una hoja de ruta para que los equipos técnicos de los gobiernos locales, en conjunto con otros actores sociales, puedan elaborar un diagnóstico de espacios públicos, y puedan planificar, implementar y evaluar estratégicamente intervenciones de reactivación de espacios públicos que contribuyan a incrementar el bienestar de los ciudadanos.
Ciência e quadrinhos: algumas relações possíveis
Authors: Fioresi Claudia Almeida , Gomes Jean Francisco De Oliveira
Published: April 2022

A circulac?a?o dos quadrinhos na sociedade é uma prática cada vez mais comum, tanto entre crianças, jovens como adultos. Acreditando nas potencialidades dos quadrinhos, como um elemento motivador, e por poder despertar o interesse dos estudantes, buscamos neste artigo discutir sobre possíveis aproximações dos quadrinhos com o ensino de ciências. Para tanto, realizamos um recorte de revistas de quadrinhos explorando algumas histórias populares, como as produzidas pela Marvel, DC comics e Manga?s, demostrando como os mesmos podem se relacionar com alguns conceitos científicos. A partir de nosso recorte buscamos um entrelaçamento entre ficção científica especulativa, o conhecimento científico e o ensino de ciências, apresentando algumas possibilidades e alternativas para a inserção desta linguagem na sala de aula. Além disso, acreditamos que este estudo pode fomentar novas pesquisas que pensem em relações e articulações possíveis entre a ciência e quadrinhos.
Notas sobre o procedimento hermenêutico de Benedito Nunes
Authors: De Castro Fábio Fonseca
Published: April 2022

O artigo reflete sobre o procedimento hermenêutico utilizado pelo professor, crítico e filósofo Benedito Nunes em sua obra. Reconstruindo diálogos do autor com Nunes, procura-se compreender as peculiaridades da sua abordagem interpretativa em relação a três pensadores com os quais sua obra dialoga em permanência, Heidegger, Gadamer e Ricoeur. Compreende- se que a abordagem de Nunes procura superar alguns impasses da hermenêutica contemporânea por meio da problemática heideggeriana da co-referencialidade entre fundamento e abismo, tema presente na questão geral do conflito ôntico ontológico, compreendendo-se fundamento como aquilo que é a fundamentação do ser relativamente ao ente, e abismo como o ser enquanto tal. A partir dessa equação, considerando o estatuto da co-presença (Zusammengeböririgkeit) entre os dois elementos, entende-se que a ação de interpretação de Nunes valoriza não apenas as dinâmicas de desvelamento, mas também de ocultamento do ser e, em o fazendo, permite uma abertura da hermenêutica para a alteridade.